Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001859-TA|BGIBMGA001859-PA|IPR003593|AAA ATPase,
IPR013594|Dynein heavy chain, N-terminal region 1, IPR013602|Dynein
heavy chain, N-terminal region 2, IPR011704|ATPase associated with
various cellular activities, AAA-5, IPR004273|Dynein heavy chain
(4153 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AB095937-1|BAC23113.2| 3051|Homo sapiens KIAA2017 protein protein. 1437 0.0
AK095581-1|BAC04579.1| 828|Homo sapiens protein ( Homo sapiens ... 976 0.0
AB040936-1|BAA96027.2| 4464|Homo sapiens KIAA1503 protein protein. 897 0.0
AF257737-1|AAF69004.1| 4486|Homo sapiens ciliary dynein heavy ch... 869 0.0
AJ404468-1|CAB94756.1| 4486|Homo sapiens axonemal dynein heavy c... 866 0.0
AY045575-1|AAK92217.1| 4624|Homo sapiens axonemal dynein heavy c... 863 0.0
AL391415-3|CAI21588.1| 4695|Homo sapiens dynein, axonemal, heavy... 849 0.0
AL391415-2|CAI21587.1| 4176|Homo sapiens dynein, axonemal, heavy... 849 0.0
AL353700-3|CAI20294.1| 4695|Homo sapiens dynein, axonemal, heavy... 849 0.0
AL353700-2|CAI20293.1| 4176|Homo sapiens dynein, axonemal, heavy... 849 0.0
AL353700-1|CAI20292.1| 4490|Homo sapiens dynein, axonemal, heavy... 849 0.0
AL035690-5|CAI19770.1| 4695|Homo sapiens dynein, axonemal, heavy... 849 0.0
AL035690-1|CAI19769.1| 4490|Homo sapiens dynein, axonemal, heavy... 849 0.0
AL035555-4|CAI19822.1| 4695|Homo sapiens dynein, axonemal, heavy... 849 0.0
AL035555-3|CAI19821.1| 4176|Homo sapiens dynein, axonemal, heavy... 849 0.0
AL035555-1|CAI19819.1| 4490|Homo sapiens dynein, axonemal, heavy... 849 0.0
AL034345-4|CAI42436.1| 4695|Homo sapiens dynein, axonemal, heavy... 849 0.0
AL034345-3|CAI42435.1| 4176|Homo sapiens dynein, axonemal, heavy... 849 0.0
AL034345-1|CAI42433.1| 4490|Homo sapiens dynein, axonemal, heavy... 849 0.0
AF356519-1|AAK60620.1| 4490|Homo sapiens axonemal dynein heavy c... 849 0.0
AB002355-1|BAA21573.2| 2992|Homo sapiens KIAA0357 protein. 788 0.0
AF327442-1|AAL37427.1| 4024|Homo sapiens ciliary dynein heavy ch... 778 0.0
AB023161-1|BAA76788.2| 4031|Homo sapiens KIAA0944 protein protein. 776 0.0
AK125796-1|BAC86296.1| 617|Homo sapiens protein ( Homo sapiens ... 727 0.0
AF494040-1|AAM12861.1| 4116|Homo sapiens axonemal heavy chain dy... 726 0.0
AJ320497-1|CAC60121.1| 4523|Homo sapiens axonemal beta heavy cha... 721 0.0
AB037831-1|BAA92648.2| 4355|Homo sapiens KIAA1410 protein protein. 669 0.0
AB046823-1|BAB13429.2| 1659|Homo sapiens KIAA1603 protein protein. 668 0.0
AC068919-1|AAY14995.1| 2536|Homo sapiens unknown protein. 657 0.0
BC117259-1|AAI17260.1| 1581|Homo sapiens LOC200383 protein protein. 648 0.0
AB051484-1|BAB21788.2| 2182|Homo sapiens KIAA1697 protein protein. 648 0.0
AK128517-1|BAC87476.1| 901|Homo sapiens protein ( Homo sapiens ... 636 0.0
AY682080-1|AAT74625.1| 4646|Homo sapiens dynein, cytoplasmic, he... 556 e-157
AB002323-1|BAA20783.3| 4658|Homo sapiens KIAA0325 protein protein. 556 e-157
AC004002-1|AAB96346.2| 1031|Homo sapiens Homo sapiens dynein, ax... 524 e-147
AY221994-1|AAO43053.1| 1964|Homo sapiens heat shock regulated-1 ... 524 e-147
AK074130-1|BAB84956.1| 1457|Homo sapiens FLJ00203 protein protein. 524 e-147
AK128592-1|BAC87517.1| 1093|Homo sapiens protein ( Homo sapiens ... 487 e-136
AJ000522-1|CAA04165.1| 1179|Homo sapiens axonemal dynein heavy c... 442 e-122
AB082528-1|BAC02706.2| 1685|Homo sapiens KIAA1997 protein protein. 436 e-121
AY049075-1|AAL06603.1| 514|Homo sapiens dynein heavy chain prot... 428 e-118
AK023766-1|BAB14671.1| 892|Homo sapiens protein ( Homo sapiens ... 428 e-118
BX538093-1|CAD98012.1| 1732|Homo sapiens hypothetical protein pr... 426 e-118
AK131453-1|BAD18598.1| 1300|Homo sapiens protein ( Homo sapiens ... 397 e-109
AK097746-1|BAC05158.1| 679|Homo sapiens protein ( Homo sapiens ... 395 e-108
AL096732-1|CAB46377.1| 965|Homo sapiens hypothetical protein pr... 356 8e-97
AC005078-1|AAC78616.2| 1020|Homo sapiens Homo sapiens dynein, ax... 319 1e-85
AK128065-1|BAC87257.1| 821|Homo sapiens protein ( Homo sapiens ... 317 6e-85
U53530-1|AAB09727.1| 897|Homo sapiens cytoplasmic dynein heavy ... 306 1e-81
BC019878-1|AAH19878.1| 314|Homo sapiens DNAH3 protein protein. 246 1e-63
X99947-1|CAA68207.1| 798|Homo sapiens dynein-related protein pr... 226 1e-57
BC128421-1|AAI28422.1| 798|Homo sapiens DNAH9 protein protein. 226 1e-57
BC128261-1|AAI28262.1| 798|Homo sapiens DNAH9 protein protein. 226 1e-57
AC104600-1|AAY24051.1| 1270|Homo sapiens unknown protein. 226 1e-57
AL162738-2|CAI95642.2| 582|Homo sapiens novel protein protein. 226 2e-57
AK125475-1|BAC86173.1| 913|Homo sapiens protein ( Homo sapiens ... 223 1e-56
U53531-1|AAB09728.1| 655|Homo sapiens cytoplasmic dynein 2 heav... 214 5e-54
AL117428-1|CAB55917.1| 591|Homo sapiens hypothetical protein pr... 206 1e-51
AK126059-1|BAC86419.1| 933|Homo sapiens protein ( Homo sapiens ... 201 4e-50
AL357912-1|CAI95150.1| 234|Homo sapiens dynein, axonemal, heavy... 200 1e-49
AK026756-1|BAB15543.1| 394|Homo sapiens protein ( Homo sapiens ... 200 1e-49
AC002394-2|AAC05809.1| 573|Homo sapiens Gene product with simil... 200 1e-49
BC029567-1|AAH29567.1| 507|Homo sapiens DNAH7 protein protein. 190 9e-47
Z83805-1|CAB06059.1| 177|Homo sapiens axonemal dynein heavy cha... 175 3e-42
AK095579-1|BAC04578.1| 806|Homo sapiens protein ( Homo sapiens ... 175 3e-42
Z83801-1|CAB06055.1| 169|Homo sapiens axonemal dynein heavy cha... 163 9e-39
Z83802-1|CAB06056.1| 179|Homo sapiens axonemal dynein heavy cha... 162 3e-38
Z83800-1|CAB06054.1| 179|Homo sapiens cytoplasmic dynein heavy ... 155 4e-36
U53532-1|AAB09729.1| 197|Homo sapiens cytoplasmic dynein 3 heav... 155 4e-36
BC015442-1|AAH15442.1| 551|Homo sapiens LOC200383 protein protein. 153 2e-35
AC098975-1|AAX93115.1| 326|Homo sapiens unknown protein. 153 2e-35
AF015265-1|AAC27542.1| 377|Homo sapiens axonemal dynein protein. 151 5e-35
AC010087-1|AAX93108.1| 224|Homo sapiens unknown protein. 139 2e-31
AJ132089-1|CAA10562.1| 101|Homo sapiens axonemal dynein, heavy ... 138 4e-31
AK027182-1|BAB15685.1| 366|Homo sapiens protein ( Homo sapiens ... 135 3e-30
AK054657-1|BAB70785.1| 333|Homo sapiens protein ( Homo sapiens ... 134 6e-30
AJ132085-1|CAA10558.1| 143|Homo sapiens axonemal dynein, heavy ... 131 6e-29
AJ132083-1|CAA10556.1| 143|Homo sapiens axonemal dynein, heavy ... 126 1e-27
U20552-1|AAB50020.1| 161|Homo sapiens dynein heavy chain, isoty... 126 2e-27
AJ132084-1|CAA10557.1| 143|Homo sapiens axonemal dynein, heavy ... 121 5e-26
BC021297-1|AAH21297.1| 832|Homo sapiens DYNC1H1 protein protein. 116 2e-24
L23958-1|AAA16065.1| 141|Homo sapiens dynein heavy chain protein. 113 1e-23
AC013274-1|AAY14776.1| 213|Homo sapiens unknown protein. 107 1e-21
AK074178-1|BAB85004.1| 1007|Homo sapiens FLJ00251 protein protein. 105 3e-21
AL137619-1|CAB70845.1| 617|Homo sapiens hypothetical protein pr... 95 5e-18
AJ132086-1|CAA10559.1| 101|Homo sapiens axonemal dynein, heavy ... 95 6e-18
AJ132088-1|CAA10561.1| 101|Homo sapiens axonemal dynein, heavy ... 94 1e-17
AJ132087-1|CAA10560.1| 101|Homo sapiens axonemal dynein, heavy ... 94 1e-17
U83573-1|AAB82762.1| 102|Homo sapiens axonemal dynein heavy cha... 92 3e-17
Z83799-1|CAB06053.1| 101|Homo sapiens axonemal dynein heavy cha... 92 4e-17
U83570-1|AAB82760.1| 83|Homo sapiens axonemal dynein heavy cha... 89 4e-16
U61736-1|AAC50700.1| 80|Homo sapiens dynein heavy chain protein. 87 1e-15
BC037496-1|AAH37496.1| 504|Homo sapiens DYNC2H1 protein protein. 86 3e-15
AK021818-1|BAB13905.1| 553|Homo sapiens protein ( Homo sapiens ... 86 3e-15
AJ132094-1|CAB46445.1| 83|Homo sapiens axonemal dynein, heavy ... 85 4e-15
Z83803-1|CAB06057.1| 101|Homo sapiens axonemal dynein heavy cha... 84 9e-15
Z83806-1|CAB06060.1| 107|Homo sapiens axonemal dynein heavy cha... 83 2e-14
U83571-1|AAB82761.1| 89|Homo sapiens axonemal dynein heavy cha... 83 2e-14
AL034345-2|CAI42434.1| 134|Homo sapiens dynein, axonemal, heavy... 82 4e-14
U61735-1|AAC50699.1| 79|Homo sapiens dynein heavy chain protein. 82 5e-14
Z83804-1|CAB06058.1| 101|Homo sapiens axonemal dynein heavy cha... 80 1e-13
U61737-1|AAC50701.1| 77|Homo sapiens dynein heavy chain protein. 77 1e-12
BC117303-1|AAI17304.1| 1021|Homo sapiens dynein heavy chain doma... 77 1e-12
BC117301-1|AAI17302.1| 1021|Homo sapiens dynein heavy chain doma... 77 1e-12
AK057314-1|BAB71423.1| 1021|Homo sapiens protein ( Homo sapiens ... 77 1e-12
AJ132090-1|CAA10563.1| 57|Homo sapiens axonemal dynein, heavy ... 76 3e-12
AJ132091-1|CAA10564.1| 57|Homo sapiens axonemal dynein, heavy ... 74 1e-11
AB231765-1|BAE46899.1| 94|Homo sapiens hypothetical protein pr... 74 1e-11
U61739-1|AAC50703.1| 55|Homo sapiens dynein heavy chain protein. 68 8e-10
U61740-1|AAC50704.1| 54|Homo sapiens dynein heavy chain protein. 66 3e-09
AL162738-1|CAI95641.1| 207|Homo sapiens novel protein protein. 65 6e-09
AJ132093-1|CAB46444.1| 67|Homo sapiens axonemal dynein, heavy ... 65 6e-09
U61738-1|AAC50702.1| 55|Homo sapiens dynein heavy chain protein. 61 7e-08
U61741-1|AAC50705.1| 55|Homo sapiens dynein heavy chain protein. 58 7e-07
AK125990-1|BAC86379.1| 1205|Homo sapiens protein ( Homo sapiens ... 55 6e-06
U83574-1|AAB82763.1| 50|Homo sapiens axonemal dynein heavy cha... 53 3e-05
U83569-1|AAB82759.1| 37|Homo sapiens axonemal dynein heavy cha... 48 5e-04
BC034225-1|AAH34225.1| 872|Homo sapiens DNAH2 protein protein. 47 0.002
BC112284-1|AAI12285.1| 566|Homo sapiens dynein, axonemal, heavy... 45 0.007
BC105107-1|AAI05108.1| 566|Homo sapiens dynein, axonemal, heavy... 45 0.007
AK097776-1|BAC05170.1| 566|Homo sapiens protein ( Homo sapiens ... 45 0.007
DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein. 41 0.11
BC043398-1|AAH43398.1| 805|Homo sapiens CEP290 protein protein. 41 0.11
AK023677-1|BAB14636.1| 574|Homo sapiens protein ( Homo sapiens ... 41 0.11
AF317887-1|AAK01919.1| 589|Homo sapiens monoclonal antibody 3H1... 41 0.11
BC004130-1|AAH04130.1| 446|Homo sapiens calcium binding and coi... 39 0.33
AK025632-1|BAB15196.1| 720|Homo sapiens protein ( Homo sapiens ... 38 0.77
U22897-1|AAA75297.1| 446|Homo sapiens NDP52 protein. 38 1.0
CR456763-1|CAG33044.1| 446|Homo sapiens NDP52 protein. 38 1.0
BC015893-1|AAH15893.1| 446|Homo sapiens calcium binding and coi... 38 1.0
AK223227-1|BAD96947.1| 446|Homo sapiens nuclear domain 10 prote... 38 1.0
AK222666-1|BAD96386.1| 429|Homo sapiens nuclear domain 10 prote... 38 1.0
BC044830-1|AAH44830.1| 258|Homo sapiens chromosome 10 open read... 35 7.2
X69086-1|CAA48829.1| 3433|Homo sapiens utrophin (dystrophin rela... 34 9.5
AL590704-1|CAI10894.1| 3433|Homo sapiens utrophin (homologous to... 34 9.5
AL590488-1|CAI16497.1| 3433|Homo sapiens utrophin (homologous to... 34 9.5
AL513475-1|CAI13032.1| 3433|Homo sapiens utrophin (homologous to... 34 9.5
AL513184-1|CAI40502.1| 3433|Homo sapiens utrophin (homologous to... 34 9.5
AL357149-1|CAI40388.1| 3433|Homo sapiens utrophin (homologous to... 34 9.5
AL024474-2|CAI23353.1| 3433|Homo sapiens utrophin (homologous to... 34 9.5
>AB095937-1|BAC23113.2| 3051|Homo sapiens KIAA2017 protein protein.
Length = 3051
Score = 1437 bits (3561), Expect = 0.0
Identities = 736/1337 (55%), Positives = 920/1337 (68%), Gaps = 51/1337 (3%)
Query: 1105 EDRGYTLNPCDDIVVKLDDDSMSLQSMAASQFIGPFLTVVQTWEHRLSLISEIIEEWMAT 1164
++RGY L D+I+ LDD++ +LQS++ S+F+GPFL V WE LSLI E+IE WM
Sbjct: 1 QERGYILGSVDEIIQSLDDNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLV 60
Query: 1165 QRKWLYLEGIFVGGDIRTQLPEEAKKFDDIDRAFRKIMLDTAKRLNVVDCCTIGGRLEEF 1224
QRKW+YLE IF+GGDIR+QLPEEAKKFD+ID+ F++IM +T K + CC RL +
Sbjct: 61 QRKWMYLESIFIGGDIRSQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDL 120
Query: 1225 VNLGLGLQSSKIIRSASSDVTRKQINLSQAIAWADRASLSLVPRSHLHAKAQAKRDTFSC 1284
N+ GL+ K +S + + K+ + +D LS++ S D C
Sbjct: 121 QNVSEGLE--KCQKSLNDYLDSKRNAFPRFFFISDDELLSILGSS----------DPL-C 167
Query: 1285 VQP----MFDNIRALDLYVDHTNRPVAAKMISAEGEIMDFRNVVYTEGRVEDWMNLVLVE 1340
VQ M+DNI +L + + + MISAEGE+M+FR +V EGRVEDWM VL E
Sbjct: 168 VQEHMIKMYDNIASLRFNDGDSGEKLVSAMISAEGEVMEFRKIVRAEGRVEDWMTAVLNE 227
Query: 1341 MRHTNKFITKKAIFYYGKNWKVPRTDWILEYQGMVCLAANGVWWTAETEETFLRIKKGNK 1400
MR TN+ ITK+AIF Y ++ R DW+L YQGMV LAA+ VWWT E E+ F + +KG K
Sbjct: 228 MRRTNRLITKEAIFRYCEDRS--RVDWMLLYQGMVVLAASQVWWTWEVEDVFHKAQKGEK 285
Query: 1401 RAMKEHLQQQNEQLDGLVVKVRQDLSSNDRLKFRTITTIDVHARDIIEGFVRDNITEAAE 1460
+AMK + ++ + Q+D LV ++ LS NDR K+ T+ IDVHARDI++ F+R +I EA E
Sbjct: 286 QAMKNYGRKMHRQIDELVTRITMPLSKNDRKKYNTVLIIDVHARDIVDSFIRGSILEARE 345
Query: 1461 FEWESQLRFYWLKKDDNLWIRQCTGVFEYGYEYMGLNGRLVITPLTDRIYLTITQALTMQ 1520
F+WESQLRFYW ++ D L IRQCTG F YGYEYMGLNGRLVITPLTDRIYLT+TQAL+M
Sbjct: 346 FDWESQLRFYWDREPDELNIRQCTGTFGYGYEYMGLNGRLVITPLTDRIYLTLTQALSMY 405
Query: 1521 LXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDE 1580
L DLAKALGLLCVVTNCGEGMD+RAVG+I +GL QCGAWGCFDE
Sbjct: 406 LGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDE 465
Query: 1581 FNRIDISVLSVISTQLQCIRSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDS 1640
FNRID SVLSVIS+Q+Q IR+AL+ +L F GQEI++DS
Sbjct: 466 FNRIDASVLSVISSQIQTIRNALIHQLTTFQFE-------------------GQEISLDS 506
Query: 1641 KVGIFITMNPGYAGRTELPESVKALFRPVVCILPDLEMICQISLFSDGFLTAKVLAKKMT 1700
++GIFITMNPGYAGRTELPESVKALFRPVV I+PDL+ IC+I LFS+GFL AK LAKKMT
Sbjct: 507 RMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKTLAKKMT 566
Query: 1701 VLYKVAREQLSKQSHYDWGLRALTAVLRMAGKLRRDSPGLSEIMVLMRALRDMNHPKFVF 1760
VLYK+AREQLSKQ HYD+GLRAL +VL MAG+L+R S L E +VLMRALRDMN PKFVF
Sbjct: 567 VLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMNLPKFVF 626
Query: 1761 EDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEKDGYVVLPHQVDKVVQLYETMMTR 1820
EDVPLFLGLI DLFPGL+CPRV YP+FN AV +VLE++GY VLP QVDKVVQ++ETM+TR
Sbjct: 627 EDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFETMLTR 686
Query: 1821 HCTMLVGPTGGGKTVILHCLVKAQTNLGLPTKLTVVNPKACSVIELYGILDPVTRDWTDG 1880
H TM+VGPT GGK+V+++ L +AQT LGL TKL ++NPKA SVIELYGILDP TRDWTDG
Sbjct: 687 HTTMVVGPTRGGKSVVINTLCQAQTKLGLTTKLYILNPKAVSVIELYGILDPTTRDWTDG 746
Query: 1881 LYSKIFREMNRPAEKNERRYSLFDGDVDALWIENMNSVMDDNKLLTLANGERIRLAPYCS 1940
+ S IFRE+N+P +K ER+Y LFDGDVDALW+ENMNSVMDDN+LLTLANGERIRL +C+
Sbjct: 747 VLSNIFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRLQAHCA 806
Query: 1941 LLFEVGDLNYASPATVSRAGMVFVDPKNLGYEPYWERWLSTRSNEEEREQLSGLFEHYVP 2000
LLFEVGDL YASPATVSR GMV+VDPKNL Y PYW++W++ N+ E+ L+ LFE YVP
Sbjct: 807 LLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSLFEKYVP 866
Query: 2001 GAINYIVFGMFGLQQQTPLKTIVPQTPLNLVMQLCYMISGLLPNNEDTNMEIDKTVVECV 2060
++ IV G+ +Q LKTIVPQT LN+V QL M+ LL + D ++EC
Sbjct: 867 YLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALLEGEIE-----DLDLLECY 921
Query: 2061 FMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVEDNPEKKATTKHFPMGFPTLYDYCLE 2120
F+ ++Y SLGA+++++GR FD YIK+ + V D A P PTLYD+ +
Sbjct: 922 FLEALYCSLGASLLEDGRMKFDEYIKRLASLSTV-DTEGVWANPGELPGQLPTLYDFHFD 980
Query: 2121 LTTKLWEAWDWLVPEYEHDRDMKFPAILVPTVDTLRLTWLIKIMESIIQQMNF--SSRTS 2178
W W LVPEY H + KF ILV TVDT R TW+++ M I Q + F S TS
Sbjct: 981 NKRNQWVPWSKLVPEYIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVGESGTS 1040
Query: 2179 SMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMP--IVSHNNQCVPSLCSTRVQTL 2236
+N + + T R N+ + R+
Sbjct: 1041 KTATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKRLLVF 1100
Query: 2237 ---LSHPLVDTYGTQQPIALLKLLFERKGFYDRGKDLNWKNLKDIGFLAAMGKAGGGRND 2293
++ P VD YGTQQPIALLKLL E+ YDRGK+LN K+++D+GF+AAMGKAGGGRN+
Sbjct: 1101 MDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGGGRNE 1160
Query: 2294 VDPRFISMFSVYNLQFPSENTLRHIYVSILKGHFEIFPEEIQGIVEKIVQMTLDLYKIII 2353
VDPRFIS+FSV+N+ FPSE +L IY SILKGH F E I + K+ TL LYK I+
Sbjct: 1161 VDPRFISLFSVFNVPFPSEESLHLIYSSILKGHTSTFHESIVAVSGKLTFCTLALYKNIV 1220
Query: 2354 VELPPTPAKFHYIFNLRDLSRIAAGMCLTHANYFSEKRTVVRCWRNEFTRVICDRLINQQ 2413
+LPPTP+KFHYIFNLRDLSR+ G+ LT+ F +VR WRNE RV DRLI++
Sbjct: 1221 QDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHDRLISET 1280
Query: 2414 DNELMRGHIQEHVARYF 2430
D +L++ HI V +F
Sbjct: 1281 DKQLVQQHIGSLVVEHF 1297
Score = 1355 bits (3358), Expect = 0.0
Identities = 642/1089 (58%), Positives = 811/1089 (74%), Gaps = 4/1089 (0%)
Query: 2684 CRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKIPEEFRPIIVEHVVHVHMSVARY 2743
CR+FPG+VNNT IDW PWP QAL AVA FL IP E +V+HVV VH SV Y
Sbjct: 1524 CRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAENIENVVKHVVLVHQSVDHY 1583
Query: 2744 SAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQLED 2803
S +FL +LRR+NYVTPK+Y+DF+ Y LL+EK +AQC+RL GGL K+ EA +QL++
Sbjct: 1584 SQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGGLDKLKEATIQLDE 1643
Query: 2804 LNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVEKXX 2863
LN KLA QK+++AE++ CE LL+EI+ T EI EQ+KVIA+EK
Sbjct: 1644 LNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAE 1703
Query: 2864 XXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVIIRGIKDVSWKG 2923
K+D+TEIRSFA PP+ VQ VCEC++I++G K+++WK
Sbjct: 1704 AETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILIMKGYKELNWKT 1763
Query: 2924 AKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKK-SKKLDTMQQISKAGYGLLKFVTA 2982
AKG+M+DPNFLR+L E++ D ITQ+QVK +K +K + + M+ +SKAG G+LKFV A
Sbjct: 1764 AKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEA 1823
Query: 2983 VLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQKTLDGLNNRYETAMMRR 3042
V+GYC + L + E+ +QK L+ L +YE A++ +
Sbjct: 1824 VMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEK 1883
Query: 3043 QELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSRLIGNCLLATSFLSYTG 3102
Q+LQEE ++M RRL+AADKL+SGL SE RW DL L + +L+G+CLL +FLSY G
Sbjct: 1884 QKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRRVKLLGDCLLCAAFLSYEG 1943
Query: 3103 PFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSGWNSEGLPPDELSVQNG 3162
F++ FR M+ W D++ER IPL+ PF +E LT++VE+S W S+GLPPDELSVQNG
Sbjct: 1944 AFTWEFRDEMVNRIWQNDILEREIPLSQPFRLESLLTDDVEISRWGSQGLPPDELSVQNG 2003
Query: 3163 ILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLRQLEMAIKYGMPVLFQD 3222
ILTTRASRFPLCIDPQ QAL WIK+KE KNNL+V SFNDP FL+QLEM+IKYG P LF+D
Sbjct: 2004 ILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFRD 2063
Query: 3223 VNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPNFRMYLTTKLANPQFNPAAYAKA 3282
V+EYIDPV+DNVLEKNIKV GR F++LG EVDYD NFR+YL TKLANP+++P+ + KA
Sbjct: 2064 VDEYIDPVIDNVLEKNIKVSQGRQFIILGDKEVDYDSNFRLYLNTKLANPRYSPSVFGKA 2123
Query: 3283 VVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANKSLLSGLEDSLLRELATS 3342
+VINYTVT++GLEDQLLSV+V ER +LEEQRE LI ETS NK+LL LEDSLLRELATS
Sbjct: 2124 MVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETSENKNLLKDLEDSLLRELATS 2183
Query: 3343 TGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRDGYRPVAKRGSILFFVLS 3402
TGNMLDNV+LV+TLE TKSKA EV EKL+LAE T DI++LRDGYRP A+RG+ILFFVLS
Sbjct: 2184 TGNMLDNVDLVHTLEETKSKATEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILFFVLS 2243
Query: 3403 DMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDMLTKNVYDYGCTGIFERH 3462
+MA VNSMYQYSL ++L+VF SL+K++P+ IL+KRL+NI+D LT ++Y++GCTG+FERH
Sbjct: 2244 EMALVNSMYQYSLIAFLEVFRLSLKKSLPDSILMKRLRNIMDTLTFSIYNHGCTGLFERH 2303
Query: 3463 KLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLEKSARSSPAPWMPAQGWQDIMKLSSD 3522
KLLFSF M IK+EQ+E V Q +LDFF+KGN+SLEKS R P W+ QGW+DI+ LS
Sbjct: 2304 KLLFSFNMTIKIEQAEGRVPQEELDFFLKGNISLEKSKRKKPCAWLSDQGWEDIILLSEM 2363
Query: 3523 FPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLKPFELLMLLRCFRVDRIYR 3582
F D F LPDD+ WQEW+D D+ E +P Y + PF+ L++LRCFRVDR+YR
Sbjct: 2364 FSDNFGQLPDDVENNQTVWQEWYDLDSLEQFPVPLGYDNNITPFQKLLILRCFRVDRVYR 2423
Query: 3583 ALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPGSDPTADLMKLADRCGFGG 3642
A+TDY+TVTMGE+Y+ PP+IS + I EQ+TP +P+VFILSPGSDP DLMKLA+R GFGG
Sbjct: 2424 AVTDYVTVTMGEKYVQPPMISFEAIFEQSTPHSPIVFILSPGSDPATDLMKLAERSGFGG 2483
Query: 3643 GKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFLRELEKQLELMTKPHPEYR 3702
+ K+L++GQGQE AL LLE A++ GQWL+LQNCHLLV +L++LEK LE +TKPHP++R
Sbjct: 2484 NRLKFLAMGQGQEKVALQLLETAVARGQWLMLQNCHLLVKWLKDLEKSLERITKPHPDFR 2543
Query: 3703 LWLTTDPTPTFPIGILQRSLK---EPPNGLKLNLRNTYFKMRARALEECPHPQFKKLVYV 3759
LWLTTDPT FPIGILQ+SLK EPPNGLKLN+R TYFK+ L++CPHP FK LVYV
Sbjct: 2544 LWLTTDPTKGFPIGILQKSLKVVTEPPNGLKLNMRATYFKISHEMLDQCPHPAFKPLVYV 2603
Query: 3760 LAFFHAVVQ 3768
LAFFHAVVQ
Sbjct: 2604 LAFFHAVVQ 2612
Score = 510 bits (1258), Expect = e-143
Identities = 227/390 (58%), Positives = 295/390 (75%)
Query: 3764 HAVVQVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDE 3823
+ + +VMYGG YM+EY+G+F+FD FQPFHF+++ DY IP E+++
Sbjct: 2662 YLIGEVMYGGRAIDSFDRRILTIYMDEYLGDFIFDTFQPFHFFRNKEVDYKIPVGDEKEK 2721
Query: 3824 YIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEAGGAMSREDFID 3883
+++ I+ LPLANTPEVFGLHPNAEIGY++QA R+MW HL+ELQPQT E+ +SR+D+I
Sbjct: 2722 FVEAIEALPLANTPEVFGLHPNAEIGYYTQAARDMWAHLLELQPQTGESSSGISRDDYIG 2781
Query: 3884 NIAVDVLSKLPTLYEIWRVRKQFEMNITPTLVVLLQELERFNRLISRMGSTLSLLRKALA 3943
+A ++ +K+P ++++ +VRK+ ++PT VVLLQELERFN+L+ RM +L+ L++ALA
Sbjct: 2782 QVAKEIENKMPKVFDLDQVRKRLGTGLSPTSVVLLQELERFNKLVVRMTKSLAELQRALA 2841
Query: 3944 GEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTKQYTDWATVEEPV 4003
GE+GM LD+V+ SLF G +P +WR LAP T K LG WM +F+ R QY W T EP
Sbjct: 2842 GEVGMSNELDDVARSLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEPS 2901
Query: 4004 VIWLSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVTSWVSADEIEERPVTGCYVRGL 4063
V+WLSGLHIPESYL A VQ CR WPLDRST FT+VT + ADE+ ER GC+V GL
Sbjct: 2902 VMWLSGLHIPESYLTALVQATCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGL 2961
Query: 4064 YLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRTPVYTTSQRRNAMG 4123
YLEGA WD+++GCL +S PKVLV +LPI+ IIPIE H+LKLQNT RTPVYTTS RRNAMG
Sbjct: 2962 YLEGADWDIEKGCLIKSKPKVLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAMG 3021
Query: 4124 VGLVFESDLWTTEHCSHWILQGVCLIMNTD 4153
VGLVFE+DL+TT H SHW+LQGVCL +N+D
Sbjct: 3022 VGLVFEADLFTTRHISHWVLQGVCLTLNSD 3051
Score = 229 bits (559), Expect = 2e-58
Identities = 105/200 (52%), Positives = 145/200 (72%)
Query: 2495 VLRDPMLFGDYRNALDEEEIRYYEDLLDYEAIYFLFQEILDEYNERNAKMSIVLFEDCLE 2554
V+RDP+LFGD++ AL E E R YED+ DYEA LFQEIL+EYNE N KM++VLF+D LE
Sbjct: 1304 VMRDPILFGDFQMALHEGEPRIYEDIQDYEAAKALFQEILEEYNESNTKMNLVLFDDALE 1363
Query: 2555 HLTRTHRILRMDRGNAMXXXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMK 2614
HLTR HRI+RMDRG+A+ +LAAF A CE+FEI ++R Y+EN+F++D+K
Sbjct: 1364 HLTRVHRIIRMDRGHALLVGVGGSGKQSLSRLAAFTASCEVFEILLSRGYSENSFREDLK 1423
Query: 2615 RMYLQLGVDNKKTVFLFTAAQILEEGFLEFINNILMIGMIPALFGDDEKDSIINSVRNDS 2674
+YL+LG++NK +FLFT A + EEGFLE INN+L G++PALF ++EK+SI++ + ++
Sbjct: 1424 SLYLKLGIENKAMIFLFTDAHVAEEGFLELINNMLTSGIVPALFSEEEKESILSQIGQEA 1483
Query: 2675 SDAGYGIAKCRSFPGLVNNT 2694
G G AK + VN +
Sbjct: 1484 LKQGMGPAKESVWQYFVNKS 1503
>AK095581-1|BAC04579.1| 828|Homo sapiens protein ( Homo sapiens cDNA
FLJ38262 fis, clone FCBBF3001594, moderately similar to
Chlamydomonas reinhardtii dhc1 gene for 1-alpha dynein ).
Length = 828
Score = 976 bits (2415), Expect = 0.0
Identities = 472/817 (57%), Positives = 601/817 (73%), Gaps = 1/817 (0%)
Query: 2684 CRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKIPEEFRPIIVEHVVHVHMSVARY 2743
CR+FPG+VNNT IDW PWP QAL AVA FL IP E +V+HVV VH SV Y
Sbjct: 12 CRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAENIENVVKHVVLVHQSVDHY 71
Query: 2744 SAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQLED 2803
S +FL +LRR+NYVTPK+Y+DF+ Y LL+EK +AQC+RL GGL K+ EA +QL++
Sbjct: 72 SQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGGLDKLKEATIQLDE 131
Query: 2804 LNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVEKXX 2863
LN KLA QK+++AE++ CE LL+EI+ T EI EQ+KVIA+EK
Sbjct: 132 LNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAE 191
Query: 2864 XXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVIIRGIKDVSWKG 2923
K+D+TEIRSFA PP+ VQ VCEC++I++G K+++WK
Sbjct: 192 AETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILIMKGYKELNWKT 251
Query: 2924 AKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKK-SKKLDTMQQISKAGYGLLKFVTA 2982
AKG+M+DPNFLR+L E++ D ITQ+QVK +K +K + + M+ +SKAG G+LKFV A
Sbjct: 252 AKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSKAGLGMLKFVEA 311
Query: 2983 VLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQKTLDGLNNRYETAMMRR 3042
V+GYC + L + E+ +QK L+ L +YE A++ +
Sbjct: 312 VMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEK 371
Query: 3043 QELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSRLIGNCLLATSFLSYTG 3102
Q+LQEE ++M RRL+AADKL+SGL SE RW DL L + +L+G+CLL +FLSY G
Sbjct: 372 QKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRRVKLLGDCLLCAAFLSYEG 431
Query: 3103 PFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSGWNSEGLPPDELSVQNG 3162
F++ FR M+ W D++ER IPL+ PF +E LT++VE+S W S+GLPPDELSVQNG
Sbjct: 432 AFTWEFRDEMVNRIWQNDILEREIPLSQPFRLESLLTDDVEISRWGSQGLPPDELSVQNG 491
Query: 3163 ILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLRQLEMAIKYGMPVLFQD 3222
ILTTRASRFPLCIDPQ QAL WIK+KE KNNL+V SFNDP FL+QLEM+IKYG P LF+D
Sbjct: 492 ILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFRD 551
Query: 3223 VNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPNFRMYLTTKLANPQFNPAAYAKA 3282
V+EYIDPV+DNVLEKNIKV GR F++LG EVDYD NFR+YL TKLANP+++P+ + KA
Sbjct: 552 VDEYIDPVIDNVLEKNIKVSQGRQFIILGDKEVDYDSNFRLYLNTKLANPRYSPSVFGKA 611
Query: 3283 VVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANKSLLSGLEDSLLRELATS 3342
+VINYTVT++GLEDQLLSV+V ER +LEEQRE LI ETS NK+LL LEDSLLRELATS
Sbjct: 612 MVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETSENKNLLKDLEDSLLRELATS 671
Query: 3343 TGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRDGYRPVAKRGSILFFVLS 3402
TGNMLDNV+LV+TLE TKSKA EV EKL+LAE T DI++LRDGYRP A+RG+ILFFVLS
Sbjct: 672 TGNMLDNVDLVHTLEETKSKATEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILFFVLS 731
Query: 3403 DMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDMLTKNVYDYGCTGIFERH 3462
+MA VNSMYQYSL ++L+VF SL+K++P+ IL+KRL+NI+D LT ++Y++GCTG+FERH
Sbjct: 732 EMALVNSMYQYSLIAFLEVFRLSLKKSLPDSILMKRLRNIMDTLTFSIYNHGCTGLFERH 791
Query: 3463 KLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLEKS 3499
KLLFSF M IK+EQ+E V Q +LDFF+KGN+SLEKS
Sbjct: 792 KLLFSFNMTIKIEQAEGRVPQEELDFFLKGNISLEKS 828
>AB040936-1|BAA96027.2| 4464|Homo sapiens KIAA1503 protein protein.
Length = 4464
Score = 897 bits (2219), Expect = 0.0
Identities = 566/1693 (33%), Positives = 889/1693 (52%), Gaps = 130/1693 (7%)
Query: 785 LEDFKLVMATITQVQQMTITAEVKYRGMQEIFHMLKQHGINVTDEDLQFAKSLEASWGSL 844
LE+ + + + ++ E + + E F +L+++ + V D L+ SL W
Sbjct: 1105 LEELGVSLQLVDALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVF 1164
Query: 845 YQTSLFRGNTLEQTKEKFSKLNVVEISNFLKELDDFVEKFDNEGPATVEDDMDRGLLLME 904
QT L L++ KEKF + +F K+ +E F+ +G T L +
Sbjct: 1165 QQTLLDSKQMLKKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQIT 1224
Query: 905 EYGKYIDELESRKKMLQAAEQLFDNPLADFSNFNRTKADYSAMDQIYKIYKAQKNAREVW 964
+ + + + L+A +F + + + A+ QI++I + + W
Sbjct: 1225 QVRAMLMAMREEENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEW 1284
Query: 965 AKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLMLDL--KMKQFKGVVPLMVSLK 1022
++ L + + F+ KL K + + ++ K++QFK +PL+ L+
Sbjct: 1285 KTGRFLILQTETMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLR 1344
Query: 1023 NEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMELHKYQDVAEEIVNHAIKELAIERG 1082
N A+RERHW ++ + ++FD + FTLE + + + ++ + EI A KELAIE
Sbjct: 1345 NPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVA 1404
Query: 1083 VKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVVKLDDDSMSLQSMAASQFIGPFLT 1142
++++ +TW + + ++G R L +++ L+D+ ++L +M AS+F+ F
Sbjct: 1405 LQNIAKTWDVTQLDIVPYKDKGHHR---LRGTEEVFQALEDNQVALSTMKASRFVKAFEK 1461
Query: 1143 VVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGGDIRTQLPEEAKKFDDIDRAFRKIM 1202
V WE LSLI E+IE + QR+W+YLE IF+G DIR QLP E+ FD ++ ++ IM
Sbjct: 1462 DVDHWERCLSLILEVIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIM 1521
Query: 1203 LDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASSDVTRKQINLSQAIAWADRAS 1262
K N + G L+ + + L+ I +S + K+ + ++
Sbjct: 1522 DRMNKDNNALRSTHHPGLLDTLIEMNTILED--IQKSLDMYLETKRHIFPRFYFLSNDDL 1579
Query: 1263 LSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYV--DHTNRPVAAKMISAEGEIMDF 1320
L ++ +S Q ++ FDNI+ L + +++ A M S +GE +DF
Sbjct: 1580 LEILGQSRNPEAVQPH------LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDF 1633
Query: 1321 RNVVYTEGRVEDWMNLVLVEMRHTNKFITKKAIFYYGKNWKVPRTDWILEYQGMVCLAAN 1380
+ V+ EG VE W+ V MR T + + + K + R W+ E+ G V + A+
Sbjct: 1634 LHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALRK-FLNKRDKWVKEWAGQVVITAS 1692
Query: 1381 GVWWTAETEETFLRIK-KGNKRAMKEHLQQQNEQLDGLVVKVRQDLSSNDRLKFRTITTI 1439
+ WTA+ + L K + +K+ +K + Q L+ +R +L+ RLK + TI
Sbjct: 1693 QIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTI 1752
Query: 1440 DVHARDIIEGFVRDNITEAAEFEWESQLRFYWLKKDDNLWIRQCTGVFEYGYEYMGLNGR 1499
++HARD++E + + + F+W SQLRFYW K D+ IRQ F+Y YEY+G +GR
Sbjct: 1753 EIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGR 1812
Query: 1500 LVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDF 1559
LVITPLTDR Y+T+T AL + DL KALG+ +V NC EG+D+
Sbjct: 1813 LVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDY 1872
Query: 1560 RAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLKRFTVNTDVLKP 1619
+++G++ +GL Q GAWGCFDEFNRI+I VLSV++ Q+ CI SAL L F +
Sbjct: 1873 KSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLTHFHFD------ 1926
Query: 1620 SQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTELPESVKALFRPVVCILPDLEMI 1679
G EI + GIFITMNPGYAGRTELPE++K++FRP+ ++PD +I
Sbjct: 1927 -------------GFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLI 1973
Query: 1680 CQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTAVLRMAGKLRRDSPG 1739
+I LF +GF K+LAKK+ LY +A +QLS+Q HYD+GLRALT++LR AGK RR P
Sbjct: 1974 AEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPD 2033
Query: 1740 LSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEKDG 1799
L++ VL+ ++RDMN K D PLF +++DLFP +E P + Y + V + + G
Sbjct: 2034 LTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIRDMG 2093
Query: 1800 YVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTV---ILHCLVKAQTNLGLPTKLTV- 1855
P + KV QLYET +RH TM+VG TG GKT IL + + G P V
Sbjct: 2094 LQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFNIVR 2153
Query: 1856 ---VNPKACSVIELYGILDPVTRDWTDGLYSKIFREMNRPAEKNERRYSLFDGDVDALWI 1912
+NPKA S+ ELYG D T +WTDG+ S + R EK + ++ LFDG VD LWI
Sbjct: 2154 EFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACAD-EKPDEKWILFDGPVDTLWI 2212
Query: 1913 ENMNSVMDDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGYE 1972
ENMNSVMDDNK+LTL NGERI + SLLFEV DL ASPATVSR GMV+ D +LG++
Sbjct: 2213 ENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYADLGWK 2272
Query: 1973 PYWERWLSTRSNEEEREQLSGLFEHYVPGAINYIVFGMFGLQQQTPLKTIVPQTPLNLVM 2032
PY + WL R + E E L +FE + + + ++ K +VP + +
Sbjct: 2273 PYVQSWLEKRP-KAEVEPLQRMFEKLINKMLAF---------KKDNCKELVPLPEYSGIT 2322
Query: 2033 QLCYMISGL-LPNN--EDTNMEIDKTVVECVFMVSMYNSLGAAIVDNGRYDFDNYIKKAC 2089
LC + S L P N + E T+VE F+ SM S+ A++ + GR D+Y+++
Sbjct: 2323 SLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLRE-- 2380
Query: 2090 PMMLVEDNPEKKATTKHFPMGFPTLYDYCLELTTKLWEAWDWLVPE-YEHDRDMKFPAIL 2148
+E + FP T+Y+Y ++ + W +++ +P+ + + + F I+
Sbjct: 2381 ----IEGS---------FP-NKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIM 2426
Query: 2149 VPTVDTLRLTWLI---------------------KIMESIIQQM----------NFSSRT 2177
VPTVDT+R +L+ I +S++Q + N S++T
Sbjct: 2427 VPTVDTVRYNYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQT 2486
Query: 2178 SSMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMPIVSHNNQCVPSLCSTRVQTLL 2237
+S +VQ +ES VEKRTK + P GK M+ F+DD+NMP
Sbjct: 2487 TSNNVQSIIESRVEKRTKGVYVPFGGKSMITFMDDLNMP--------------------- 2525
Query: 2238 SHPLVDTYGTQQPIALLKLLFERKGFYDRGKDLNWKNLKDIGFLAAMGKAGGGRNDVDPR 2297
D +G+Q P+ L++L + +YDR K K ++++ +AAMG GGGR + PR
Sbjct: 2526 ---AKDMFGSQPPLELIRLWIDYGFWYDRTKQ-TIKYIREMFLMAAMGPPGGGRTVISPR 2581
Query: 2298 FISMFSVYNLQFPSENTLRHIYVSILKGHFEIFPEEIQGIVEKIVQMTLDLYKIIIVELP 2357
S F++ N+ FP+++ + I+ +++ + F EE++ I + + TLD+Y ++
Sbjct: 2582 LRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPIGNVVTEATLDMYNTVVQRFL 2641
Query: 2358 PTPAKFHYIFNLRDLSRIAAGMCLTHANYFSEKRTVVRCWRNEFTRVICDRLINQQDNEL 2417
PTP K HY+FNLRD+S++ GM + ++ K ++ R W +E RV DRL++ D E
Sbjct: 2642 PTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDRLVDAADTEA 2701
Query: 2418 MRGHIQEHVARYF 2430
G I + + +F
Sbjct: 2702 FMGIISDKLGSFF 2714
Score = 831 bits (2056), Expect = 0.0
Identities = 468/1312 (35%), Positives = 718/1312 (54%), Gaps = 52/1312 (3%)
Query: 2499 PMLFGDYRNALDEEEIRYYEDLLDYEAIYFLFQEILDEYNERNA--KMSIVLFEDCLEHL 2556
P +FGD+ +E + YEDL D + + + L+EYN + M +VLF + +EH+
Sbjct: 2727 PPIFGDFL-----KEPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHI 2781
Query: 2557 TRTHRILRMDRGNAMXXXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRM 2616
TR R++ RGN + +LA+ F+I VT++Y + F+DD+KR+
Sbjct: 2782 TRIVRVIGQPRGNMLLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRL 2841
Query: 2617 YLQLGVDNKKTVFLFTAAQILEEGFLEFINNILMIGMIPALFGDDE----KDSIINSVR- 2671
Y Q GV+ K T F+F QI +E FLE INNIL G +P L+ DE + II+ R
Sbjct: 2842 YRQAGVELKTTSFIFVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARV 2901
Query: 2672 ---NDSSDAGYG-----------IAKC------------RSFPGLVNNTTIDWQFPWPKQ 2705
+SSD+ + I C R +P LVN TTI+W WP++
Sbjct: 2902 EQVPESSDSLFAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQE 2961
Query: 2706 ALLAVANVFLADVQK-IPEEFRPIIVEHVVHVHMSVARYSAEFLLRLRRNNYVTPKHYMD 2764
ALL VA L V E + + V +H SVA+YS + LL LRR+NYVTP Y++
Sbjct: 2962 ALLEVAEKCLIGVDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLE 3021
Query: 2765 FLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQLEDLNAKLAVQKVIVAEQTKECEI 2824
L+ Y LL EK ++AQ +L+ GL KI E +++ ++ +L K VAE K+CE
Sbjct: 3022 LLSGYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEE 3081
Query: 2825 LLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVEKXXXXXXXXXXXXXXXXXXXXXXX 2884
L I +I +
Sbjct: 3082 YLVIIVQQKREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALES 3141
Query: 2885 XXKNDITEIRSFATPPEAVQVVCECVVIIRGIKDVSWKGAKGMMADPNFLRNLQEMNCDL 2944
K DI EI+S+ PP V++V + V+I+RG + +W AK + + NF+++L + D
Sbjct: 3142 LNKKDIGEIKSYGRPPAQVEIVMQAVMILRG-NEPTWAEAKRQLGEQNFIKSLINFDKDN 3200
Query: 2945 ITQAQVKAVKTHMKKSK-KLDTMQQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXX 3003
I+ +K + + + + D + ++S A L +V A+ Y
Sbjct: 3201 ISDKVLKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAA 3260
Query: 3004 XXXYSEAVNYLASLNREIDRLQKTLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLM 3063
E LA ++ + + L+ L +Y+ + +++EL+++++ M +L A L+
Sbjct: 3261 LAQLREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLV 3320
Query: 3064 SGLSSEQKRWTEDLAALYVEQSRLIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVME 3123
SGL+ E+ RW E + L + L+G+CLLA +FLSY GPF ++R ++ + W+G + E
Sbjct: 3321 SGLAGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWE 3380
Query: 3124 RGIPLTLPFTIERNLTNEVEVSGWNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALT 3183
+P + F I+ L N +V WN +GLP D S +NGI+ TR +R+ L IDPQ QAL
Sbjct: 3381 LQVPCSPSFAIDNFLCNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALK 3440
Query: 3184 WIKKKEAKNNLKVLSFNDPQFLRQLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVES 3243
WIK E LK++ +LR LE AI +G PVL Q+V EY+DP ++ +L K++
Sbjct: 3441 WIKNMEGGQGLKIIDLQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIG 3500
Query: 3244 GRTFVMLGSTEVDYDPNFRMYLTTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVV 3303
GR + +G EV+Y+ NFR Y+TTKL+NP ++P AK ++N+ V QGLE QLL +VV
Sbjct: 3501 GRLLMRIGDKEVEYNTNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVV 3560
Query: 3304 RAERSDLEEQRESLIIETSANKSLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKA 3363
R ER +LEEQ++SL+I +A K L LED +LR L +TG++LD+V+LVNTL +K A
Sbjct: 3561 RKERPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITA 3620
Query: 3364 AEVMEKLELAEATTKDIEKLRDGYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFS 3423
EV E+LE +E T + + R+ YRP A+R SILFFVL+DM ++ MYQ+SL +Y+ +F
Sbjct: 3621 TEVTEQLETSETTEINTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFI 3680
Query: 3424 FSLRKAMPNVILVKRLKNIIDMLTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQ 3483
S+ K+ + L R+ + D T VY Y C +FERHKLLFSF M K+ ++ ++
Sbjct: 3681 LSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNM 3740
Query: 3484 AQLDFFIKGNVSLEKSAR-SSP-APWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEW 3541
+ +FF++G V L++ + +P + W+ W +I +L D F L + ++ +W
Sbjct: 3741 DEYNFFLRGGVVLDREGQMDNPCSSWLADAYWDNITEL--DKLTNFHGLMNSFEQYPRDW 3798
Query: 3542 QEWFDSDTPESAEIPNNYREKLKPFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPV 3601
W+ + PE A +P + + ++++R R DR+ +T +I +G +I PPV
Sbjct: 3799 HLWYTNAAPEKAMLPGEWENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPV 3858
Query: 3602 ISLDMIVEQTTPFTPVVFILSPGSDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSL 3661
+++ ++E +TP +P+VFILSPG DPT+ L++LA+ G +F LSLGQGQ A L
Sbjct: 3859 LNMKSVLEDSTPRSPLVFILSPGVDPTSALLQLAEHMGM-AQRFHALSLGQGQAPIAARL 3917
Query: 3662 LEGAISHGQWLILQNCHLLVSFLRELEKQLELM--TKPHPEYRLWLTTDPTPTFPIGILQ 3719
L ++ G W+ L NCHL +S++ L+K +E + PHP +RLWL++ P P FPI ILQ
Sbjct: 3918 LREGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQ 3977
Query: 3720 RSLK---EPPNGLKLNLRNTYFKMRARALEECPHP-QFKKLVYVLAFFHAVV 3767
S+K EPP GLK N+ Y M C P ++KKL++ L FFH+V+
Sbjct: 3978 VSIKMTTEPPKGLKANMTRLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVL 4029
Score = 188 bits (458), Expect = 4e-46
Identities = 119/400 (29%), Positives = 185/400 (46%), Gaps = 15/400 (3%)
Query: 3761 AFFHAVVQVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGE 3820
A + + + YGG TY+ +Y + PFH Y IP +G
Sbjct: 4072 ALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLST--PFHRLSALE-TYFIPKDGS 4128
Query: 3821 RDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQ-TSEAGGAMSRE 3879
Y ++I LP + PE FG HPNA++ + ++ L+ LQPQ T G +RE
Sbjct: 4129 LASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRAGGQTRE 4188
Query: 3880 DFIDNIAVDVLSKLPTLYEIWRVRKQFEMNITPTLVVLLQELERFNRLISRMGSTLSLLR 3939
+ + +A DV K+P + + +K ++ +P VVLLQE++R+N L+ + +L+ L
Sbjct: 4189 EKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTILFSLTDLE 4248
Query: 3940 KALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTKQYTDWAT- 3998
K + G I M L+ + + + +P +W P+ K L W R +Q+ WA+
Sbjct: 4249 KGIQGLIVMSTSLEEIFNCILDAHVPPLWGKAYPSQ-KPLAAWTQDLAMRVEQFELWASR 4307
Query: 3999 VEEPVVIWLSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVTSWVSADEIEERPVTGC 4058
PV+ WLSG P +L A +Q + R +D S + + S V + P G
Sbjct: 4308 ARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVD-SLSWEFIVSTVDDSNLVYPPKDGV 4366
Query: 4059 YVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRTPVY----- 4113
+VRGLYLEGA WD CL + P LV +P ++ P E K + P Y
Sbjct: 4367 WVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNR 4426
Query: 4114 TTSQRRNAMGVGLVFESDLWTTEHCSHWILQGVCLIMNTD 4153
S R + +G+ S T + HWI +G L+M+ D
Sbjct: 4427 AGSSDRASFVIGIDLRSGAMTPD---HWIKRGTALLMSLD 4463
Score = 60.1 bits (139), Expect = 2e-07
Identities = 42/162 (25%), Positives = 74/162 (45%), Gaps = 1/162 (0%)
Query: 361 DLTVHKLIQEYNLEFQPNFDKDLFLVIHEAELMEQLGFDVPSNVRDVAMQKSRLFYELEA 420
D + ++ QE NFDK L ++ E + E+L F+ P V +VA + L E
Sbjct: 652 DTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVNVAERAEDLRILREN 711
Query: 421 LSKIIAKYNKNASSLSPSETYLMKRHLLDMERHILPGLTRITWTALGIND-YIKDITKGE 479
L + YN+ + LSP E L K + +++ I PGL ++ W G + +I +
Sbjct: 712 LLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAFFITECRIHA 771
Query: 480 NSLQAVYQQLKMVEKEIQFLINQLQEFDLFPVVRPKNYKDPE 521
+ +Q + + K I + ++ E L + + Y+D E
Sbjct: 772 SKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLE 813
Score = 37.1 bits (82), Expect = 1.4
Identities = 48/220 (21%), Positives = 85/220 (38%), Gaps = 8/220 (3%)
Query: 57 FGLELKSIISDPTQIDDVRKRVKNLVYPIRTVDFSVFVFDNKENWDVIMGDFWNEVRYLE 116
FG + I + +I+D+ KNL + +R V + N W F ++ E
Sbjct: 450 FGAQGPQITRNLLEIEDIFH--KNL-HTLRAVRGGILDVKNT-CWHEDYNKFRAGIKDPE 505
Query: 117 DEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLSTK-FDLVMRQFIKEITAIE 175
+N I +F +R + +L F +RE+I+R K DL M F E+ +
Sbjct: 506 VMTQNLITSAFELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYM-LFNSELALVN 564
Query: 176 DKFTRYRKNPPLLRNHPPVAGAISWARALFNKMKQPIMKFQKVSELNECEQKKEAFLQYK 235
+ R +K P L +G W L ++ + + L KE+ Y+
Sbjct: 565 RE--RNKKWPDLEPYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQ 622
Query: 236 AFSKIIKEYEDTKYKEWVQDASLFCDNMMKKNILKVVFKK 275
+ I E ++EW C + +L++ +K
Sbjct: 623 QMVQAIDELVRKTFQEWTSSLDKDCIRRLDTPLLRISQEK 662
>AF257737-1|AAF69004.1| 4486|Homo sapiens ciliary dynein heavy chain 9
protein.
Length = 4486
Score = 869 bits (2149), Expect = 0.0
Identities = 540/1696 (31%), Positives = 862/1696 (50%), Gaps = 123/1696 (7%)
Query: 758 ISDLNTHVKFVDVGASLRMTINMNIKGLEDFKLVMATITQVQQMTITAEVKYRGMQEIFH 817
+++L+ +K + G L+ + +GL + +M + V++ + + +++
Sbjct: 1119 LANLDAFIKKSESGL-LKKVEKGDFQGLVE---IMGHLMAVKERQSNTDEMFEPLKQTIE 1174
Query: 818 MLKQHGINVTDEDLQFAKSLEASWGSLYQTSLFRGNTLEQTKEKFSKLNVVEISNFLKEL 877
+LK + + + + + L W ++ + ++ + + L + F E
Sbjct: 1175 LLKTYEQELPETVFKQLEELPEKWNNIKKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQ 1234
Query: 878 DDFVEKFDNEGPATVEDDMDRGLLLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNF 937
F E+F E P + +L I ++ES + + LF+ + D+
Sbjct: 1235 QQFWEQFHKEAPFRFDSIHPHQMLDARHIE--IQQMESTMASISESASLFEVNVPDYKQL 1292
Query: 938 NRTKADYSAMDQIYKIYKAQKNAREVWAKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRL 997
+ + + + +++ ++ W T W N+N +A+ +QF + R L K VR
Sbjct: 1293 RQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQFARHIRNLDKEVRA 1352
Query: 998 SSTGLMLDLKMKQFKGVVPLMVSLKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAM 1057
L+ + + + L+N A+RERHW++LM TG F M D TL ++ +
Sbjct: 1353 WDAFTGLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATGVSFTMDQDT-TLAHLLQL 1411
Query: 1058 ELHKYQDVAEEIVNHAIKELAIERGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDI 1117
+LH Y+D IV+ A KE+ +E+ +K++Q TWA + F H L +D+
Sbjct: 1412 QLHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHPRTNVP---LLCSDEDL 1468
Query: 1118 VVKLDDDSMSLQSMAASQFIGPFLTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVG 1177
+ L+D+ + LQ++ S+++ FL V W+ +LS + +I W QR W +LE IF G
Sbjct: 1469 IEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTG 1528
Query: 1178 G-DIRTQLPEEAKKFDDIDRAFRKIMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKI 1236
DIR QLP+++K+F+ ID F+++ D K NVV G E+ ++ L +
Sbjct: 1529 SEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLEDIQGRLCLCEK 1588
Query: 1237 IRSASSDVTRKQINLSQAIAWADRASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALD 1296
+ D R ++ +D + S+ A Q +R + +FDN+ +
Sbjct: 1589 ALAEYLDTKRLAFPRFYFLSSSDLLDIL----SNGTAPQQVQRH----LSKLFDNMAKMR 1640
Query: 1297 LYVDHTNRPVAAK--MISAEGEIMDFRNVVYTEGRVEDWMNLVLVEMRHTNKFITKKAIF 1354
+D + P M S E E + F G+VE W+N VL M+ T + + +
Sbjct: 1641 FQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVT 1700
Query: 1355 YYGKNWKVPRTDWILEYQGMVCLAANGVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQL 1414
Y + PR W+ ++ V L +WWT E F R+++G + AMK++ ++Q QL
Sbjct: 1701 AYEEK---PREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQL 1757
Query: 1415 DGLVVKVRQDLSSNDRLKFRTITTIDVHARDIIEGFVRDNITEAAEFEWESQLRFYWLKK 1474
L+ + LS DR K TI TIDVHARD++ + + A F W SQLR W +
Sbjct: 1758 KTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDE 1817
Query: 1475 DDNLWIRQCTGVFEYGYEYMGLNGRLVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXX 1534
+ + C F Y YEY+G RLVITPLTDR Y+T+TQ+L + +
Sbjct: 1818 VKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKT 1877
Query: 1535 XXXXDLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVIST 1594
DL +ALG+L V NC E MD+++ G I GL Q GAWGCFDEFNRI + VLSV++
Sbjct: 1878 ETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAV 1937
Query: 1595 QLQCIRSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAG 1654
Q++ I+ A+ K + F+ G+EI+++ VGIFITMNPGYAG
Sbjct: 1938 QVKSIQDAIRDKKQWFSF-------------------LGEEISLNPSVGIFITMNPGYAG 1978
Query: 1655 RTELPESVKALFRPVVCILPDLEMICQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQS 1714
RTELPE++K+LFRP ++PD E+IC+I L ++GF+ A+ LA+K LY++ +E LSKQ
Sbjct: 1979 RTELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQD 2038
Query: 1715 HYDWGLRALTAVLRMAGKLRRDSPGLSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLF 1774
HYDWGLRA+ +VL +AG L+R P E VLMR+LRD N PK V +D+P+F+GLI DLF
Sbjct: 2039 HYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLF 2098
Query: 1775 PGLECPRVGYPEFNAAVLEVLEKDGYVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKT 1834
P L+ PR P F A V + + + V KVVQL E + RH +VG G GK+
Sbjct: 2099 PALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKS 2158
Query: 1835 VILHCLVKAQTNLGLPTKLTVVNPKACSVIELYGILDPVTRDWTDGLYSKIFREMNRPAE 1894
+L L K + T +NPKA + EL+GI++P T +W DGL+S I RE+
Sbjct: 2159 QVLRSLHKTYQIMKRRPVWTDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITH 2218
Query: 1895 KNERRYSLFDGDVDALWIENMNSVMDDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPA 1954
++ L DGD+D +WIE++N+VMDDNK+LTLA+ ERI L P LLFE+ L A+PA
Sbjct: 2219 DGP-KWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPA 2277
Query: 1955 TVSRAGMVFVDPKNLGYEPYWERWLSTRSNEEEREQLSGLFEHYVPGAINYIVFGMFGLQ 2014
TVSRAG+++++P +LG+ P W+ R + ER L+ LF+ Y+P ++ +
Sbjct: 2278 TVSRAGILYINPADLGWNPPVSSWIEKREIQTERANLTILFDKYLPTCLDTL-------- 2329
Query: 2015 QQTPLKTIVPQTPLNLVMQLCYMISGLLPNNEDTNMEIDKTVVECVFMVSMYNSLGAAIV 2074
+T K I+P ++V +C+++ LL ED + K + E F+ + + G A+V
Sbjct: 2330 -RTRFKKIIPIPEQSMVQMVCHLLECLL-TTEDIPADCPKEIYEHYFVFAAIWAFGGAMV 2387
Query: 2075 DNGRYDFDNYIKKACPMMLVEDNPEKKATTKHFPMGFPTLYDYCLELTTKLWEAWDWLVP 2134
+ D+ K L E T FP T++DY ++ TK +E W LVP
Sbjct: 2388 QDQLVDYRAEFSK---WWLTE------FKTVKFP-SQGTIFDYYIDPETKKFEPWSKLVP 2437
Query: 2135 EYEHDRDMKFPAILVPTVDTLRLTWLIKIM----------------ESIIQQMNFSSRTS 2178
++E D +M A LV T +T+R+ + ++ + +S++ +S
Sbjct: 2438 QFEFDPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGKSVLVGAKLASLDP 2497
Query: 2179 SMDVQRNL-----------ESVVEK----RTKDTFGPPVGKRMLVFIDDMNMPIVSHNNQ 2223
+ +NL ++V+EK + +GPP K+++ FIDDMNMP
Sbjct: 2498 EAYLVKNLPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIYFIDDMNMP------- 2550
Query: 2224 CVPSLCSTRVQTLLSHPLVDTYGTQQPIALLKLLFERKGFYDRGKDLNWKNLKDIGFLAA 2283
VD YGT QP +++ + +YDR K L+ K + ++ +++
Sbjct: 2551 -----------------EVDAYGTVQPHTIIRQHLDYGHWYDRSK-LSLKEITNVQYVSC 2592
Query: 2284 MGKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSILKGHFEI--FPEEIQGIVEKI 2341
M G ++PR FSV+ L FP + L IY IL H ++ FP +Q + +
Sbjct: 2593 MNPTAGSFT-INPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGNFPASLQKSIPPL 2651
Query: 2342 VQMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMCLTHANYFSEKRTVVRCWRNEF 2401
+ + L ++ I PT KFHYIFNLRD + I G+ + ++R + +E
Sbjct: 2652 IDLALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHES 2711
Query: 2402 TRVICDRLINQQDNEL 2417
RV D+++ ++D +L
Sbjct: 2712 NRVYRDKMVEEKDFDL 2727
Score = 617 bits (1523), Expect = e-175
Identities = 358/1106 (32%), Positives = 595/1106 (53%), Gaps = 30/1106 (2%)
Query: 2683 KCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKIPEEFRPIIVEHVVHVHMSVAR 2742
+ R FP +VN T I W WP+QAL +V+ FL + + I + I + + VH SV +
Sbjct: 2965 RSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVKQSISKFMAFVHTSVNQ 3024
Query: 2743 YSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQLE 2802
S +L +R NY TPK +++F+ Y +LL+ + + ERL+ GL K+ + Q++
Sbjct: 3025 TSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENGLLKLHSTSAQVD 3084
Query: 2803 DLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVEKX 2862
DL AKLA Q+V + ++ ++ + L++ + T+ ++ + ++
Sbjct: 3085 DLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIMLEVKQKQK 3144
Query: 2863 XXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVII-----RGIK 2917
K ++TE++SF +PP AV V V+++ R K
Sbjct: 3145 DCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLMAPRGRVPK 3204
Query: 2918 DVSWKGAKGMMADPN-FLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLDTMQQISKAGYG 2975
D SWK AK MA + FL +L N + I + +KA++ +++ + + + S A G
Sbjct: 3205 DRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRPYLQDPEFNPEFVATKSYAAAG 3264
Query: 2976 LLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQKTLDGLNNRY 3035
L +V ++ + + A LA++ +I L + L L R+
Sbjct: 3265 LCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAIKAKIAHLNENLAKLTARF 3324
Query: 3036 ETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSRLIGNCLLAT 3095
E A + + Q+E ++ + A++L+ GL+SE RW + + ++ L G+ LL T
Sbjct: 3325 EKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWADAVQNFKQQERTLCGDILLIT 3384
Query: 3096 SFLSYTGPFSFSFRQTMIYEDWLGDV--MERGIPLTLPFTIERNLTNEVEVSGWNSEGLP 3153
+F+SY G F+ +RQ+++ W + ++ IP+T R L ++ +V+ W +EGLP
Sbjct: 3385 AFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTPALDPLRMLMDDADVAAWQNEGLP 3444
Query: 3154 PDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLRQLEMAIK 3213
D +SV+N + R+PL +DPQ Q + WIK K ++ L+V +L+ +E A++
Sbjct: 3445 ADRMSVENATILINCERWPLMVDPQLQGIKWIKNKYGED-LRVTQIGQKGYLQIIEQALE 3503
Query: 3214 YGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPNFRMYLTTKLANPQ 3273
G VL +++ E IDPV+ +L + + ++ GR F+ +G E +Y+P FR+ L TKLANP
Sbjct: 3504 AGAVVLIENLEESIDPVLGPLLGREV-IKKGR-FIKIGDKECEYNPKFRLILHTKLANPH 3561
Query: 3274 FNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANKSLLSGLED 3333
+ P A+A +IN+TVT GLEDQLL+ VV ER DLE+ + L + + K L LED
Sbjct: 3562 YQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKSDLTKQQNGFKITLKTLED 3621
Query: 3334 SLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRDGYRPVAKR 3393
SLL L++++GN L LV LE TK AAEV +K++ A+ T I + R+ YRP A R
Sbjct: 3622 SLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEAKVTEVKINEAREHYRPTAAR 3681
Query: 3394 GSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDMLTKNVYDY 3453
S+L+F+++D++ ++ MYQ+SL ++ VF ++ +A P+ L +R+ N+ID +T +VY Y
Sbjct: 3682 ASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQY 3741
Query: 3454 GCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLEKSARSSPAPWMPAQGW 3513
G+FE KL + Q+ ++ V+ +LDF ++ V ++ +SP ++ Q W
Sbjct: 3742 TIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRSPV---QTGTASPVEFLSHQAW 3798
Query: 3514 QDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLKPFELLMLLR 3573
+ LSS + F+ L DI + W+++ +S+ PE ++P ++ K + L +LR
Sbjct: 3799 GAVKVLSS--MEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNK-TALQRLCMLR 3855
Query: 3574 CFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPGSDPTADLMK 3633
R DR+ AL D++ +G +Y+ + E++ P TP+ FILSPG DP D+
Sbjct: 3856 AMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVES 3915
Query: 3634 LADRCG--FGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFLRELEKQL 3691
+ G F F +SLGQGQE A + L+ A G W+ILQN HL+ +L LEK+L
Sbjct: 3916 QGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKL 3975
Query: 3692 ELMTK-PHPEYRLWLTTDPTPT-----FPIGILQRSLK---EPPNGLKLNLRNTYFKMRA 3742
E ++ HPE+R++++ +P P+ P GIL+ S+K EPP G+ NL
Sbjct: 3976 EEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQ 4035
Query: 3743 RALEECP-HPQFKKLVYVLAFFHAVV 3767
LE C +FK +++ L +FHAVV
Sbjct: 4036 DTLEMCSRETEFKSILFALCYFHAVV 4061
Score = 184 bits (449), Expect = 5e-45
Identities = 115/386 (29%), Positives = 188/386 (48%), Gaps = 15/386 (3%)
Query: 3768 QVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDEYIDF 3827
++MYGG TY+ GEF+ + A + +P + + Y +
Sbjct: 4111 EIMYGGHITDDWDRRLCRTYL----GEFIRPEMLEGEL--SLAPGFPLPGNMDYNGYHQY 4164
Query: 3828 IDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEA--GGAMSREDFIDNI 3885
ID +P ++GLHPNAEIG+ +Q +++ ++ELQP+ S+A G +RE+ + +
Sbjct: 4165 IDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKAL 4224
Query: 3886 AVDVLSKLPTLYEIWRVRKQFEMNITPTLVVLLQELERFNRLISRMGSTLSLLRKALAGE 3945
++L ++ + I + + E TP +VV QE R N L + +L L L GE
Sbjct: 4225 LEEILERVTDEFNIPELMAKVEER-TPYIVVAFQECGRMNILTREIQRSLRELELGLKGE 4283
Query: 3946 IGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTKQYTDWA-TVEEPVV 4004
+ M + ++N+ +L+ +P+ W A + GL W + R K+ W P
Sbjct: 4284 LTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPST 4343
Query: 4005 IWLSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVTSWVSADEIEERPVTGCYVRGLY 4064
+WL+G P+S+L A +Q R WPLD+ +T + +E P G Y+ GL+
Sbjct: 4344 VWLTGFFNPQSFLTAIMQSTARKNEWPLDQIALQCDMTK-KNREEFRSPPREGAYIHGLF 4402
Query: 4065 LEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRTPVYTTSQRRNAMGV 4124
+EGA WD G + + K L +P+M+I I K ++ PVY TSQR G
Sbjct: 4403 MEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQR----GP 4458
Query: 4125 GLVFESDLWTTEHCSHWILQGVCLIM 4150
V+ +L T E+ S W+L GV L++
Sbjct: 4459 TYVWTFNLKTKENPSKWVLAGVALLL 4484
Score = 126 bits (303), Expect = 2e-27
Identities = 66/182 (36%), Positives = 101/182 (55%), Gaps = 3/182 (1%)
Query: 2497 RDPMLFGDYRNALDEEEIRYYEDLLDYEAIYFLFQEILDEYNERNAKMSIVLFEDCLEHL 2556
+ P L+ + N + E + Y + +E + E L+ +NE N M +VLFED + H+
Sbjct: 2751 QSPNLYCHFANGIGEPK---YMPVQSWELLTQTLVEALENHNEVNTVMDLVLFEDAMRHV 2807
Query: 2557 TRTHRILRMDRGNAMXXXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRM 2616
+RIL RGNA+ +LAAF + ++F+IT+ + Y FK D+ +
Sbjct: 2808 CHINRILESPRGNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASL 2867
Query: 2617 YLQLGVDNKKTVFLFTAAQILEEGFLEFINNILMIGMIPALFGDDEKDSIINSVRNDSSD 2676
L+ GV N TVFL T AQ+ +E FL IN++L G IP L+ DDE ++II++VRN+
Sbjct: 2868 CLKAGVKNLNTVFLMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKS 2927
Query: 2677 AG 2678
G
Sbjct: 2928 QG 2929
Score = 63.7 bits (148), Expect = 1e-08
Identities = 50/259 (19%), Positives = 120/259 (46%), Gaps = 12/259 (4%)
Query: 22 WEFDQPLLFTRTD-YIGTVARDLGDIIQVLIDFERIFGLELKSIISDPT--QIDDVRKRV 78
W+F L+F R D ++G + G +++ +DF ++ +E + + Q+ + +
Sbjct: 428 WDFQSSLVFVRLDGFLGRLHVVEG-LLKTALDFHKLGKVEFSGVRGNALSQQVQQMHEEF 486
Query: 79 KNLVYPIRTVDFSVFVFDNKENWDVIMGDFWNEVRYLEDEAKNYINQSFGNLRSSEEALT 138
+ + Y + + S ++ +++ + +F +V L+ Q+F + E A
Sbjct: 487 QEM-YRLLSGSSSDCLYLQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGLEHAFK 545
Query: 139 VLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEITAIEDKFTRYRKNP------PLLRNHP 192
+L R + R S K+ ++++ F K++ A+ ++++ + P+ +N P
Sbjct: 546 LLDIAGNLLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPVHKNMP 605
Query: 193 PVAGAISWARALFNKMKQPIMKFQKVSE-LNECEQKKEAFLQYKAFSKIIKEYEDTKYKE 251
VAG + WA+ L +++ P F +++ E + K +Y+ ++++YE Y++
Sbjct: 606 TVAGGLRWAQELRQRIQGPFSNFGRITHPCMESAEGKRMQQKYEDMLSLLEKYETRLYED 665
Query: 252 WVQDASLFCDNMMKKNILK 270
W + S + + +LK
Sbjct: 666 WCRTVSEKSQYNLSQPLLK 684
Score = 43.2 bits (97), Expect = 0.021
Identities = 37/127 (29%), Positives = 59/127 (46%), Gaps = 5/127 (3%)
Query: 374 EFQPNFDKDLFLVIHEAELMEQLGFD-VPSNVRDVAMQKSRLFY-ELEALSKIIAK-YNK 430
E NF+ L V+ E +E +P AM SR FY +L A +++A YNK
Sbjct: 691 EITINFNPQLISVLKEMSYLEPREMKHMPETA--AAMFSSRDFYRQLVANLELMANWYNK 748
Query: 431 NASSLSPSETYLMKRHLLDMERHILPGLTRITWTALGINDYIKDITKGENSLQAVYQQLK 490
+L E L++ L +++ + + W GI DY+ +IT + L+ Q+ K
Sbjct: 749 VMKTLLEVEFPLVEEELQNIDLRLRAAEETLNWKTEGICDYVTEITSSIHDLEQRIQKTK 808
Query: 491 MVEKEIQ 497
+EIQ
Sbjct: 809 DNVEEIQ 815
>AJ404468-1|CAB94756.1| 4486|Homo sapiens axonemal dynein heavy chain
9 protein.
Length = 4486
Score = 866 bits (2142), Expect = 0.0
Identities = 532/1673 (31%), Positives = 856/1673 (51%), Gaps = 77/1673 (4%)
Query: 758 ISDLNTHVKFVDVGASLRMTINMNIKGLEDFKLVMATITQVQQMTITAEVKYRGMQEIFH 817
+++L+ +K + G L+ + +GL + +M + V++ + + +++
Sbjct: 1119 LANLDAFIKKSESGL-LKKVEKGDFQGLVE---IMGHLMAVKERQSNTDEMFEPLKQTIE 1174
Query: 818 MLKQHGINVTDEDLQFAKSLEASWGSLYQTSLFRGNTLEQTKEKFSKLNVVEISNFLKEL 877
+LK + + + + + L W ++ + ++ + + L + F E
Sbjct: 1175 LLKTYEQELPETVFKQLEELPEKWNNIKKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQ 1234
Query: 878 DDFVEKFDNEGPATVEDDMDRGLLLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNF 937
F E+F E P + +L I ++ES + + LF+ + D+
Sbjct: 1235 QQFWEQFHKEAPFRFDSIHPHQMLDARHIE--IQQMESTMASISESASLFEVNVPDYKQL 1292
Query: 938 NRTKADYSAMDQIYKIYKAQKNAREVWAKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRL 997
+ + + + +++ ++ W T W N+N +A+ +QF + R L K VR
Sbjct: 1293 RQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQFARHIRNLDKEVRA 1352
Query: 998 SSTGLMLDLKMKQFKGVVPLMVSLKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAM 1057
L+ + + + L+N A+RERHW++LM TG F M D TL ++ +
Sbjct: 1353 WDAFTGLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATGVSFTMDQDT-TLAHLLQL 1411
Query: 1058 ELHKYQDVAEEIVNHAIKELAIERGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDI 1117
+LH Y+D IV+ A KE+ +E+ +K++Q TWA + F H L +D+
Sbjct: 1412 QLHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHPRTNVP---LLCSDEDL 1468
Query: 1118 VVKLDDDSMSLQSMAASQFIGPFLTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVG 1177
+ L+D+ + LQ++ S+++ FL V W+ +LS + +I W QR W +LE IF G
Sbjct: 1469 IEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTG 1528
Query: 1178 G-DIRTQLPEEAKKFDDIDRAFRKIMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKI 1236
DIR QLP+++K+F+ ID F+++ D K NVV G E+ ++ L +
Sbjct: 1529 SEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLEDIQGRLCLCEK 1588
Query: 1237 IRSASSDVTRKQINLSQAIAWADRASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALD 1296
+ D R ++ +D + S+ A Q +R + +FDN+ +
Sbjct: 1589 ALAEYLDTKRLAFPRFYFLSSSDLLDIL----SNGTAPQQVQRH----LSKLFDNMAKMR 1640
Query: 1297 LYVDHTNRPVAAK--MISAEGEIMDFRNVVYTEGRVEDWMNLVLVEMRHTNKFITKKAIF 1354
+D + P M S E E + F G+VE W+N VL M+ T + + +
Sbjct: 1641 FQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVT 1700
Query: 1355 YYGKNWKVPRTDWILEYQGMVCLAANGVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQL 1414
Y + PR W+ ++ V L +WWT E F R+++G + AMK++ ++Q QL
Sbjct: 1701 AYEEK---PREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQL 1757
Query: 1415 DGLVVKVRQDLSSNDRLKFRTITTIDVHARDIIEGFVRDNITEAAEFEWESQLRFYWLKK 1474
L+ + LS DR K TI TIDVHARD++ + + A F W SQLR W +
Sbjct: 1758 KTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDE 1817
Query: 1475 DDNLWIRQCTGVFEYGYEYMGLNGRLVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXX 1534
+ + C F Y YEY+G RLVITPLTDR Y+T+TQ+L + +
Sbjct: 1818 VKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKT 1877
Query: 1535 XXXXDLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVIST 1594
DL +ALG+L V NC E MD+++ G I GL Q GAWGCFDEFNRI + VLSV++
Sbjct: 1878 ETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAV 1937
Query: 1595 QLQCIRSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAG 1654
Q++ I+ A+ K + F+ G+EI+++ VGIFITMNPGYAG
Sbjct: 1938 QVKSIQDAIRDKKQWFSF-------------------LGEEISLNPSVGIFITMNPGYAG 1978
Query: 1655 RTELPESVKALFRPVVCILPDLEMICQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQS 1714
RTELPE++K+LFRP ++PD E+IC+I L ++GF+ A+ LA+K LY++ +E LSKQ
Sbjct: 1979 RTELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQD 2038
Query: 1715 HYDWGLRALTAVLRMAGKLRRDSPGLSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLF 1774
HYDWGLRA+ +VL +AG L+R P E VLMR+LRD N PK V +D+P+F+GLI DLF
Sbjct: 2039 HYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLF 2098
Query: 1775 PGLECPRVGYPEFNAAVLEVLEKDGYVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKT 1834
P L+ PR P F A V + + + V KVVQL E + RH +VG G GK+
Sbjct: 2099 PALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKS 2158
Query: 1835 VILHCLVKAQTNLGLPTKLTVVNPKACSVIELYGILDPVTRDWTDGLYSKIFREMNRPAE 1894
+L L K + T +NPKA + EL+GI++P T +W DGL+S I RE+
Sbjct: 2159 QVLRSLHKTYQIMKRRPVWTDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITH 2218
Query: 1895 KNERRYSLFDGDVDALWIENMNSVMDDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPA 1954
++ L DGD+D +WIE++N+VMDDNK+LTLA+ ERI L P LLFE+ L A+PA
Sbjct: 2219 DGP-KWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPA 2277
Query: 1955 TVSRAGMVFVDPKNLGYEPYWERWLSTRSNEEEREQLSGLFEHYVPGAINYIVFGMFGLQ 2014
TVSRAG+++++P +LG+ P W+ R + ER L+ LF+ Y+P ++ +
Sbjct: 2278 TVSRAGILYINPADLGWNPPVSSWIEKREIQTERANLTILFDKYLPTCLDTL-------- 2329
Query: 2015 QQTPLKTIVPQTPLNLVMQLCYMISGLLPNNEDTNMEIDKTVVECVFMVSMYNSLGAAIV 2074
+T K I+P ++V +C+++ LL ED + K + E F+ + + G A+V
Sbjct: 2330 -RTRFKKIIPIPEQSMVQMVCHLLECLL-TTEDIPADCPKEIYEHYFVFAAIWAFGGAMV 2387
Query: 2075 DNGRYDFDNYIKKACPMMLVEDNPEKKATTKHFPMGFPTLYDYCLELTTKLWEAWDWLVP 2134
+ D+ K L E T FP T++DY ++ TK +E W LVP
Sbjct: 2388 QDQLVDYRAEFSK---WWLTE------FKTVKFP-SQGTIFDYYIDPETKKFEPWSKLVP 2437
Query: 2135 EYEHDRDMKFPAILVPTVDTLRLTWLIKIM---ESIIQQMNFSSRTSSMDVQRNLESVVE 2191
++E D +M A LV T +T+R+ + ++ + + + + + S+ V L S+
Sbjct: 2438 QFEFDPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGKSVLVGAKLASLDP 2497
Query: 2192 KR--TKDT-FGPPVGKRMLVFIDDMNMPIVSHNNQCVPSLCSTRVQTL--LSHPLVDTYG 2246
+ K+ F ML + + + + N P + + ++ P VD YG
Sbjct: 2498 EAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPG-NKKLIYFIDDMNMPEVDAYG 2556
Query: 2247 TQQPIALLKLLFERKGFYDRGKDLNWKNLKDIGFLAAMGKAGGGRNDVDPRFISMFSVYN 2306
T QP +++ + +YDR K L+ K + ++ +++ M G ++PR FSV+
Sbjct: 2557 TVQPHTIIRQHLDYGHWYDRSK-LSLKEITNVQYVSCMNPTAGSFT-INPRLQRHFSVFV 2614
Query: 2307 LQFPSENTLRHIYVSILKGHFEI--FPEEIQGIVEKIVQMTLDLYKIIIVELPPTPAKFH 2364
L FP + L IY IL H ++ FP +Q + ++ + L ++ I PT KFH
Sbjct: 2615 LSFPGADALSSIYSIILTQHLKLGNFPASLQKSIPPLIDLALAFHQKIATTFLPTGIKFH 2674
Query: 2365 YIFNLRDLSRIAAGMCLTHANYFSEKRTVVRCWRNEFTRVICDRLINQQDNEL 2417
YIFNLRD + I G+ + ++R + +E RV D+++ ++D +L
Sbjct: 2675 YIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRDKMVEEKDFDL 2727
Score = 617 bits (1523), Expect = e-175
Identities = 358/1106 (32%), Positives = 595/1106 (53%), Gaps = 30/1106 (2%)
Query: 2683 KCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKIPEEFRPIIVEHVVHVHMSVAR 2742
+ R FP +VN T I W WP+QAL +V+ FL + + I + I + + VH SV +
Sbjct: 2965 RSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVKQSISKFMAFVHTSVNQ 3024
Query: 2743 YSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQLE 2802
S +L +R NY TPK +++F+ Y +LL+ + + ERL+ GL K+ + Q++
Sbjct: 3025 TSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENGLLKLHSTSAQVD 3084
Query: 2803 DLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVEKX 2862
DL AKLA Q+V + ++ ++ + L++ + T+ ++ + ++
Sbjct: 3085 DLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIMLEVKQKQK 3144
Query: 2863 XXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVII-----RGIK 2917
K ++TE++SF +PP AV V V+++ R K
Sbjct: 3145 DCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLMAPRGRVPK 3204
Query: 2918 DVSWKGAKGMMADPN-FLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLDTMQQISKAGYG 2975
D SWK AK MA + FL +L N + I + +KA++ +++ + + + S A G
Sbjct: 3205 DRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRPYLQDPEFNPEFVATKSYAAAG 3264
Query: 2976 LLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQKTLDGLNNRY 3035
L +V ++ + + A LA++ +I L + L L R+
Sbjct: 3265 LCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAIKAKIAHLNENLAKLTARF 3324
Query: 3036 ETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSRLIGNCLLAT 3095
E A + + Q+E ++ + A++L+ GL+SE RW + + ++ L G+ LL T
Sbjct: 3325 EKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWADAVQNFKQQERTLCGDILLIT 3384
Query: 3096 SFLSYTGPFSFSFRQTMIYEDWLGDV--MERGIPLTLPFTIERNLTNEVEVSGWNSEGLP 3153
+F+SY G F+ +RQ+++ W + ++ IP+T R L ++ +V+ W +EGLP
Sbjct: 3385 AFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTPALDPLRMLMDDADVAAWQNEGLP 3444
Query: 3154 PDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLRQLEMAIK 3213
D +SV+N + R+PL +DPQ Q + WIK K ++ L+V +L+ +E A++
Sbjct: 3445 ADRMSVENATILINCERWPLMVDPQLQGIKWIKNKYGED-LRVTQIGQKGYLQIIEQALE 3503
Query: 3214 YGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPNFRMYLTTKLANPQ 3273
G VL +++ E IDPV+ +L + + ++ GR F+ +G E +Y+P FR+ L TKLANP
Sbjct: 3504 AGAVVLIENLEESIDPVLGPLLGREV-IKKGR-FIKIGDKECEYNPKFRLILHTKLANPH 3561
Query: 3274 FNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANKSLLSGLED 3333
+ P A+A +IN+TVT GLEDQLL+ VV ER DLE+ + L + + K L LED
Sbjct: 3562 YQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKSDLTKQQNGFKITLKTLED 3621
Query: 3334 SLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRDGYRPVAKR 3393
SLL L++++GN L LV LE TK AAEV +K++ A+ T I + R+ YRP A R
Sbjct: 3622 SLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEAKVTEVKINEAREHYRPAAAR 3681
Query: 3394 GSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDMLTKNVYDY 3453
S+L+F+++D++ ++ MYQ+SL ++ VF ++ +A P+ L +R+ N+ID +T +VY Y
Sbjct: 3682 ASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQY 3741
Query: 3454 GCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLEKSARSSPAPWMPAQGW 3513
G+FE KL + Q+ ++ V+ +LDF ++ V ++ +SP ++ Q W
Sbjct: 3742 TIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRSPV---QTGTASPVEFLSHQAW 3798
Query: 3514 QDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLKPFELLMLLR 3573
+ LSS + F+ L DI + W+++ +S+ PE ++P ++ K + L +LR
Sbjct: 3799 GAVKVLSS--MEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNK-TALQRLCMLR 3855
Query: 3574 CFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPGSDPTADLMK 3633
R DR+ AL D++ +G +Y+ + E++ P TP+ FILSPG DP D+
Sbjct: 3856 AMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVES 3915
Query: 3634 LADRCG--FGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFLRELEKQL 3691
+ G F F +SLGQGQE A + L+ A G W+ILQN HL+ +L LEK+L
Sbjct: 3916 QGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKL 3975
Query: 3692 ELMTK-PHPEYRLWLTTDPTPT-----FPIGILQRSLK---EPPNGLKLNLRNTYFKMRA 3742
E ++ HPE+R++++ +P P+ P GIL+ S+K EPP G+ NL
Sbjct: 3976 EEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQ 4035
Query: 3743 RALEECP-HPQFKKLVYVLAFFHAVV 3767
LE C +FK +++ L +FHAVV
Sbjct: 4036 DTLEMCSRETEFKSILFALCYFHAVV 4061
Score = 185 bits (450), Expect = 3e-45
Identities = 115/386 (29%), Positives = 188/386 (48%), Gaps = 15/386 (3%)
Query: 3768 QVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDEYIDF 3827
++MYGG TY+ GEF+ + A + +P + + Y +
Sbjct: 4111 EIMYGGHITDDWDRRLCRTYL----GEFIRPEMLEGEL--SLAPGFPLPGNMDYNGYHQY 4164
Query: 3828 IDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEA--GGAMSREDFIDNI 3885
ID +P ++GLHPNAEIG+ +Q +++ ++ELQP+ S+A G +RE+ + +
Sbjct: 4165 IDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKAL 4224
Query: 3886 AVDVLSKLPTLYEIWRVRKQFEMNITPTLVVLLQELERFNRLISRMGSTLSLLRKALAGE 3945
++L ++ + I + + E TP +VV QE R N L + +L L L GE
Sbjct: 4225 LEEILERVTDEFNIPELMAKVEER-TPYIVVAFQECGRMNILTREIQRSLRELELGLKGE 4283
Query: 3946 IGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTKQYTDWA-TVEEPVV 4004
+ M + ++N+ +L+ +P+ W A + GL W + R K+ W P
Sbjct: 4284 LTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPST 4343
Query: 4005 IWLSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVTSWVSADEIEERPVTGCYVRGLY 4064
+WL+G P+S+L A +Q R WPLD+ +T + +E P G Y+ GL+
Sbjct: 4344 VWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTK-KNREEFRSPPREGAYIHGLF 4402
Query: 4065 LEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRTPVYTTSQRRNAMGV 4124
+EGA WD G + + K L +P+M+I I K ++ PVY TSQR G
Sbjct: 4403 MEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQR----GP 4458
Query: 4125 GLVFESDLWTTEHCSHWILQGVCLIM 4150
V+ +L T E+ S W+L GV L++
Sbjct: 4459 TYVWTFNLKTKENPSKWVLAGVALLL 4484
Score = 126 bits (303), Expect = 2e-27
Identities = 66/182 (36%), Positives = 101/182 (55%), Gaps = 3/182 (1%)
Query: 2497 RDPMLFGDYRNALDEEEIRYYEDLLDYEAIYFLFQEILDEYNERNAKMSIVLFEDCLEHL 2556
+ P L+ + N + E + Y + +E + E L+ +NE N M +VLFED + H+
Sbjct: 2751 QSPNLYCHFANGIGEPK---YMPVQSWELLTQTLVEALENHNEVNTVMDLVLFEDAMRHV 2807
Query: 2557 TRTHRILRMDRGNAMXXXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRM 2616
+RIL RGNA+ +LAAF + ++F+IT+ + Y FK D+ +
Sbjct: 2808 CHINRILESPRGNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASL 2867
Query: 2617 YLQLGVDNKKTVFLFTAAQILEEGFLEFINNILMIGMIPALFGDDEKDSIINSVRNDSSD 2676
L+ GV N TVFL T AQ+ +E FL IN++L G IP L+ DDE ++II++VRN+
Sbjct: 2868 CLKAGVKNLNTVFLMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKS 2927
Query: 2677 AG 2678
G
Sbjct: 2928 QG 2929
Score = 63.7 bits (148), Expect = 1e-08
Identities = 50/259 (19%), Positives = 120/259 (46%), Gaps = 12/259 (4%)
Query: 22 WEFDQPLLFTRTD-YIGTVARDLGDIIQVLIDFERIFGLELKSIISDPT--QIDDVRKRV 78
W+F L+F R D ++G + G +++ +DF ++ +E + + Q+ + +
Sbjct: 428 WDFQSSLVFVRLDGFLGRLHVVEG-LLKTALDFHKLGKVEFSGVRGNALSQQVQQMHEEF 486
Query: 79 KNLVYPIRTVDFSVFVFDNKENWDVIMGDFWNEVRYLEDEAKNYINQSFGNLRSSEEALT 138
+ + Y + + S ++ +++ + +F +V L+ Q+F + E A
Sbjct: 487 QEM-YRLLSGSSSDCLYLQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGLEHAFK 545
Query: 139 VLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEITAIEDKFTRYRKNP------PLLRNHP 192
+L R + R S K+ ++++ F K++ A+ ++++ + P+ +N P
Sbjct: 546 LLDIAGNLLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPVHKNMP 605
Query: 193 PVAGAISWARALFNKMKQPIMKFQKVSE-LNECEQKKEAFLQYKAFSKIIKEYEDTKYKE 251
VAG + WA+ L +++ P F +++ E + K +Y+ ++++YE Y++
Sbjct: 606 TVAGGLRWAQELRQRIQGPFSNFGRITHPCMESAEGKRMQQKYEDMLSLLEKYETRLYED 665
Query: 252 WVQDASLFCDNMMKKNILK 270
W + S + + +LK
Sbjct: 666 WCRTVSEKSQYNLSQPLLK 684
Score = 43.2 bits (97), Expect = 0.021
Identities = 37/127 (29%), Positives = 59/127 (46%), Gaps = 5/127 (3%)
Query: 374 EFQPNFDKDLFLVIHEAELMEQLGFD-VPSNVRDVAMQKSRLFY-ELEALSKIIAK-YNK 430
E NF+ L V+ E +E +P AM SR FY +L A +++A YNK
Sbjct: 691 EITINFNPQLISVLKEMSYLEPREMKHMPETA--AAMFSSRDFYRQLVANLELMANWYNK 748
Query: 431 NASSLSPSETYLMKRHLLDMERHILPGLTRITWTALGINDYIKDITKGENSLQAVYQQLK 490
+L E L++ L +++ + + W GI DY+ +IT + L+ Q+ K
Sbjct: 749 VMKTLLEVEFPLVEEELQNIDLRLRAAEETLNWKTEGICDYVTEITSSIHDLEQRIQKTK 808
Query: 491 MVEKEIQ 497
+EIQ
Sbjct: 809 DNVEEIQ 815
>AY045575-1|AAK92217.1| 4624|Homo sapiens axonemal dynein heavy chain
DNAH5 protein.
Length = 4624
Score = 863 bits (2134), Expect = 0.0
Identities = 544/1664 (32%), Positives = 866/1664 (52%), Gaps = 94/1664 (5%)
Query: 778 INMNIKGLEDFKLVMATITQVQQMTITAEVKYRGMQEIFHMLKQHGINVTDEDLQFAKSL 837
+N IK L+D ++ MA + ++++ I+ + + ++E + +L ++G+ + E++ +L
Sbjct: 1243 LNRPIKDLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIAREEIDKVDTL 1302
Query: 838 EASWGSLYQTSLFRGNTLEQTKEKFSKLNVVEISNFLKELDDFVEKFDNEGPATV----E 893
+W L + N L + F K + + FL++ F +D GP +
Sbjct: 1303 HYAWEKLLARAGEVQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGPMASGLKPQ 1362
Query: 894 DDMDRGLLLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNFNRTKADYSAMDQIYKI 953
+ DR ++ ++ D + + E+LF P + K + + +IY +
Sbjct: 1363 EASDRLIMFQNQF----DNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQKIYTL 1418
Query: 954 YKAQKNAREVWAKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLMLDLKMKQFKG 1013
Y + + LW +N + + + + +F RKLP+ ++ L L + F
Sbjct: 1419 YNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDLKKIIDDFSE 1478
Query: 1014 VVPLMVSLKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMELHKYQDVAEEIVNHA 1073
PL+ + ++AM ERHW+ + TG D+ + F L N+ L KY++ E+I A
Sbjct: 1479 CCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDICISA 1538
Query: 1074 IKELAIERGVKDVQETWANISFSVSRHFNRGED--RGYTLNPCDDIVVKLDDDSMSLQSM 1131
+KE IE+ +K V W N +F+ RGE RG + +I+ ++D M L S+
Sbjct: 1539 VKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRG---DSTSEIIANMEDSLMLLGSL 1595
Query: 1132 AASQFIGPFLTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGGDIRTQLPEEAKKF 1191
++++ PF +Q W LS ++IIE WM Q W+YLE +FVGGDI QLP+EAK+F
Sbjct: 1596 LSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGGDIAKQLPKEAKRF 1655
Query: 1192 DDIDRAFRKIMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASSDVTRKQINL 1251
+ID+++ KIM + +VV CC L + + L Q +S + + +K++
Sbjct: 1656 SNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLD-QLEICQKSLTGYLEKKRLCF 1714
Query: 1252 SQAIAWADRASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYVDHTNRPVAAKMI 1311
+ +D A L ++ ++ QA + +FDNI+++ + +R ++
Sbjct: 1715 PRFFFVSDPALLEILGQASDSHTIQAH------LLNVFDNIKSVKFHEKIYDRILSIS-- 1766
Query: 1312 SAEGEIMDFRNVVYTEGRVEDWMNLVLVEMRHTNKFITKKAIFYYGKNWKVPRTDWILEY 1371
S EGE ++ V EG VE W+N +L E + + + ++A + T+++ +
Sbjct: 1767 SQEGETIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETG-FQLTEFLSSF 1825
Query: 1372 QGMVCLAANGVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQLDGLVVKVRQDLSSNDRL 1431
V L + WT ++EE LR K +K+ M++ Q E L+ L+ +DLSS +R+
Sbjct: 1826 PAQVGLLGIQMIWTRDSEEA-LRNAKFDKKIMQKTNQAFLELLNTLIDVTTRDLSSTERV 1884
Query: 1432 KFRTITTIDVHARDIIEGFVRDNITEAAEFEWESQLRFYWLKKDDNLWIRQCTGVFEYGY 1491
K+ T+ TI VH RDI + +I +FEW Q RFY+ + D + I F Y
Sbjct: 1885 KYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQN 1944
Query: 1492 EYMGLNGRLVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVT 1551
E++G RLVITPLTDR Y+T+ QAL M + D+ + LG VV
Sbjct: 1945 EFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVF 2004
Query: 1552 NCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLKRFT 1611
NC + MDFR +G+I GL Q G+WGCFDEFNRID+ VLSV + Q+ I + K F
Sbjct: 2005 NCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSF- 2063
Query: 1612 VNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTELPESVKALFRPVVC 1671
+ TD G + M+ + G+F+TMNPGYAGR ELPE++K FR V
Sbjct: 2064 IFTD-----------------GDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAM 2106
Query: 1672 ILPDLEMICQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTAVLRMAG 1731
++PD ++I ++ L S GF+ VLA+K LYK+ EQLSKQ HYD+GLR + +VLR G
Sbjct: 2107 MVPDRQIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLG 2166
Query: 1732 KLRRDSPGLSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAV 1791
+R +P +E ++MR LRDMN K + ED PLFL LI+DLFP + + GYPE AA+
Sbjct: 2167 AAKRANPMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAI 2226
Query: 1792 LEVLEKDGYVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNLGLPT 1851
+E+ G + P KV+QL+ET RH M +GP+G GKT +H L++A T+ G P
Sbjct: 2227 SRQVEEAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMTDCGKPH 2286
Query: 1852 KLTVVNPKACSVIELYGILDPVTRDWTDGLYSKIFREMNRPAEKNERRYSLFDGDVDALW 1911
+ +NPKA + +++G LD T DWTDG++S ++R+ R A+K E + + DG VDA+W
Sbjct: 2287 REMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLR-AKKGEHIWIILDGPVDAIW 2345
Query: 1912 IENMNSVMDDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGY 1971
IEN+NSV+DDNK LTLANG+RI +AP C ++FE +++ ASPATVSR GMVF+ L +
Sbjct: 2346 IENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDW 2405
Query: 1972 EPYWERWLSTRSNEEEREQLSGLFEHYVPGAINYIVFGMFGLQQQTPLKTIVPQTPLNLV 2031
P E +L RS +E E L L+ P + + Q K V + ++
Sbjct: 2406 SPILEGFLKKRS-PQEAEILRQLYTESFPDLYRFCI-------QNLEYKMEVLEA--FVI 2455
Query: 2032 MQLCYMISGLLPNNEDTNMEIDKTVVECVFMVSMYNSLGAAIVDNGRYDFDNYIKKACPM 2091
Q M+ GL+P E E+ + + +F+ ++ S GAA+ +GR + +++ P
Sbjct: 2456 TQSINMLQGLIPLKEQGG-EVSQAHLGRLFVFALLWSAGAALELDGRRRLELWLRSR-PT 2513
Query: 2092 MLVEDNPEKKATTKHFPMG-FPTLYDYCLELTTKLWEAWDWLVPEYEHDRDM--KFPAIL 2148
+E P P G T +DY + W W+ EY + D ++ +IL
Sbjct: 2514 GTLELPP---------PAGPGDTAFDYYV-APDGTWTHWNTRTQEYLYPSDTTPEYGSIL 2563
Query: 2149 VPTVDTLRLTWLIKIMESIIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPVGKRMLV 2208
VP VD +R +LI ++I +Q + Q ++V+ K + P +
Sbjct: 2564 VPNVDNVRTDFLI---QTIAKQ---GKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIKSL 2617
Query: 2209 FIDDMNMPIVSHNNQCVPSLCSTRVQTL---------------LSHPLVDTYGTQQPIAL 2253
P++ + + S R+ T ++ P+++ +G Q +
Sbjct: 2618 NFSSATTPLMF--QRTIESYVDKRMGTTYGPPAGKKMTVFIDDVNMPIINEWGDQVTNEI 2675
Query: 2254 LKLLFERKGFYDRGKDLNWKNLKDIGFLAAMGKAGGGRNDVDPRFISMFSVYNLQFPSEN 2313
++ L E+ GFY+ K + ++ DI FLAAM GGGRND+ R FS++N PSE
Sbjct: 2676 VRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSEA 2735
Query: 2314 TLRHIYVSILKGHF---EIFPEEIQGIVEKIVQMTLDLYKIIIVELPPTPAKFHYIFNLR 2370
++ I+ I GH+ F EE++ V K+V +T L+++ +++ PTPAKFHY+FNLR
Sbjct: 2736 SVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFNLR 2795
Query: 2371 DLSRIAAGMCLTHANYFSEKRTVVRCWRNEFTRVICDRLINQQD 2414
DLSR+ GM T + E +++ W++E RVI DR D
Sbjct: 2796 DLSRVWQGMLNTTSEVIKEPNDLLKLWKHECKRVIADRFTVSSD 2839
Score = 668 bits (1651), Expect = 0.0
Identities = 367/1102 (33%), Positives = 591/1102 (53%), Gaps = 27/1102 (2%)
Query: 2687 FPGLVNNTTIDWQFPWPKQALLAVANVFLADVQ-KIPEEFRPIIVEHVVHVHMSVARYSA 2745
FP L++ TIDW WPK AL+AV+ FL E + +V+ + VA
Sbjct: 3102 FPALISGCTIDWFSRWPKDALVAVSEHFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCV 3161
Query: 2746 EFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQLEDLN 2805
++ R RR+ +VTPK Y+ F+ Y + EK + R+ GL K+ EA+ + L+
Sbjct: 3162 DYFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAALS 3221
Query: 2806 AKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVEKXXXX 2865
+L ++ + + +++LKE++ + I+ +K
Sbjct: 3222 KELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKVKDRAQAIVDSISKDKAIAE 3281
Query: 2866 XXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVII--RGIKDV---- 2919
+DI +R+ PP + + +CV+++ R + V
Sbjct: 3282 EKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDL 3341
Query: 2920 -------SWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLDTMQQISK 2971
SW+ + +M NFL+NLQ+ D I + ++ + + + ++T +++
Sbjct: 3342 EKSCTMPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCG 3401
Query: 2972 AGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQKTLDGL 3031
GL + A+ + + + A+ L E+D Q LD +
Sbjct: 3402 NVAGLCSWTKAMASFFSINKEVLPLKANLVVQENRHLLAMQDLQKAQAELDDKQAELDVV 3461
Query: 3032 NNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSRLIGNC 3091
YE AM +Q L E+ + ++ A L+SGL+ E++RWTE + RL+G+
Sbjct: 3462 QAEYEQAMTEKQTLLEDAERCRHKMQTASTLISGLAGEKERWTEQSQEFAAQTKRLVGDV 3521
Query: 3092 LLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSGWNSEG 3151
LLAT+FLSY+GPF+ FR ++ DW ++ R IP + L + +S WN +G
Sbjct: 3522 LLATAFLSYSGPFNQEFRDLLL-NDWRKEMKARKIPFGKNLNLSEMLIDAPTISEWNLQG 3580
Query: 3152 LPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLRQLEMA 3211
LP D+LS+QNGI+ T+ASR+PL IDPQTQ WIK KE++N L++ S N F LE +
Sbjct: 3581 LPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIKNKESRNELQITSLNHKYFRNHLEDS 3640
Query: 3212 IKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTF-VMLGSTEVDYDPNFRMYLTTKLA 3270
+ G P+L +DV E +DP +DNVLE+N +++G TF V +G EVD FR+Y+TTKL
Sbjct: 3641 LSLGRPLLIEDVGEELDPALDNVLERNF-IKTGSTFKVKVGDKEVDVLDGFRLYITTKLP 3699
Query: 3271 NPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANKSLLSG 3330
NP + P A+ +I++TVT++GLEDQLL V+ E+ +LE++R L+ + +ANK +
Sbjct: 3700 NPAYTPEISARTSIIDFTVTMKGLEDQLLGRVILTEKQELEKERTHLMEDVTANKRRMKE 3759
Query: 3331 LEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRDGYRPV 3390
LED+LL L ++ G+++++ L+ L NTK A EV +KLE++ T I R+ YRPV
Sbjct: 3760 LEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEVTQKLEISAETEVQINSAREEYRPV 3819
Query: 3391 AKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDMLTKNV 3450
A RGSIL+F++++M VN MYQ SL +L +F SL +++ + I KR+ NII+ +T V
Sbjct: 3820 ATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTYEV 3879
Query: 3451 YDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLE-KSARSSPAPWMP 3509
Y Y G++E HK LF+ + +K++ + V + IKG SL+ K+ P+ W+
Sbjct: 3880 YKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEFLTLIKGGASLDLKACPPKPSKWIL 3939
Query: 3510 AQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLKPFELL 3569
W ++++LS F+ + D I++ + W+ WFD + PE +PN Y + L F L
Sbjct: 3940 DITWLNLVELSK--LRQFSDVLDQISRNEKMWKIWFDKENPEEEPLPNAYDKSLDCFRRL 3997
Query: 3570 MLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPGSDPTA 3629
+L+R + DR YI +MGE+Y ++ L+ E++ P TP++ +LS GSDPT
Sbjct: 3998 LLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLEKTWEESDPRTPLICLLSMGSDPTD 4057
Query: 3630 DLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFLRELEK 3689
++ L R + +Y+S+GQGQE A LL+ +++G W +LQNCHL + F+ EL
Sbjct: 4058 SIIALGKRLKI---ETRYVSMGQGQEVHARKLLQQTMANGGWALLQNCHLGLDFMDELMD 4114
Query: 3690 QLELMTKPHPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLNLRNTYFKMRARALE 3746
+ H +RLW+TT+ FPI +LQ S+K +PP GL+ L+ TY + L+
Sbjct: 4115 IIIETELVHDAFRLWMTTEAHKQFPITLLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLD 4174
Query: 3747 ECPHPQFKKLVYVLAFFHAVVQ 3768
Q+K ++Y +AF H+ VQ
Sbjct: 4175 VSSGSQWKPMLYAVAFLHSTVQ 4196
Score = 199 bits (485), Expect = 2e-49
Identities = 127/399 (31%), Positives = 195/399 (48%), Gaps = 15/399 (3%)
Query: 3754 KKLVYVLAFFHAVVQVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDY 3813
KK V + + ++ YGG T+ + + E +F F FY+ Y
Sbjct: 4234 KKGVSWTTIRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSENMFGP--DFSFYQGYN--- 4288
Query: 3814 VIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEAG 3873
IP D Y+ +I +LP ++PEVFGLHPNA+I Y S+ +++ ++ +QP+ + G
Sbjct: 4289 -IPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDVLDTILGIQPKDTSGG 4347
Query: 3874 GAMSREDFIDNIAVDVLSKLPTLYEIWRVRKQFEM--NITPTLVVLLQELERFNRLISRM 3931
G +RE + +A D+L KLP Y + V+++ + P + L QE++R R++S +
Sbjct: 4348 GDETREAVVARLADDMLEKLPPDYVPFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLV 4407
Query: 3932 GSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTK 3991
STL+ L+ A+ G I M L + +F+ ++P W+ A LG W I R
Sbjct: 4408 RSTLTELKLAIDGTIIMSENLRDALDCMFDARIPAWWKK-ASWISSTLGFWFTELIERNS 4466
Query: 3992 QYTDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYT-WPLDRSTQFTKVTSWVSADEI 4050
Q+T W P W++G P+ +L A Q R W LD +VT W+ D+I
Sbjct: 4467 QFTSWVFNGRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVLCNEVTKWMK-DDI 4525
Query: 4051 EERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRT 4110
P G YV GLYLEGA WD L S PKVL +P++ I E + L+
Sbjct: 4526 SAPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIRIY-AENNTLRDPRFYSC 4584
Query: 4111 PVYTTSQRRNAMGVGLVFESDLWTTEHCSHWILQGVCLI 4149
P+Y R + + V DL T + HW+L+GV L+
Sbjct: 4585 PIYKKPVRTDLNYIAAV---DLRTAQTPEHWVLRGVALL 4620
Score = 109 bits (263), Expect = 2e-22
Identities = 61/174 (35%), Positives = 89/174 (51%), Gaps = 3/174 (1%)
Query: 2496 LRD-PMLFGDYRNALDEEEIRYYEDLLDYEAIYFLFQEILDEYNE--RNAKMSIVLFEDC 2552
LRD P G+ D E + YE + + + L YNE R A M +V F D
Sbjct: 2875 LRDAPEAAGETSEEADAETPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFFADA 2934
Query: 2553 LEHLTRTHRILRMDRGNAMXXXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDD 2612
+ HL + R++R +GNA+ +LA+F AG F+IT+TR+YN + +D
Sbjct: 2935 MVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMED 2994
Query: 2613 MKRMYLQLGVDNKKTVFLFTAAQILEEGFLEFINNILMIGMIPALFGDDEKDSI 2666
+K +Y G K F+FT +I +E FLE++NN+L G + LF DE D I
Sbjct: 2995 LKVLYRTAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEI 3048
Score = 99.5 bits (237), Expect = 2e-19
Identities = 57/251 (22%), Positives = 130/251 (51%), Gaps = 15/251 (5%)
Query: 6 YKETRRNIELSGKGARWEFDQPLLFTRTDYIGTVARDLGDIIQVLIDFERIFGLELKSII 65
+ +T++ ++ + +++F + +F + + T R L II + L+ S++
Sbjct: 446 FHKTKQKLKQNPNAKQFDFSEMYIFGKFE---TFHRRLAKIIDIFTT------LKTYSVL 496
Query: 66 SDPT--QIDDVRKRVKNLVYPIRTVDFSVFVFDNKENWDVIMGDFWNEVRYLEDEAKNYI 123
D T ++D+ + + +V I+ +++ F+ K ++D +F + L +E + ++
Sbjct: 497 QDSTIEGLEDMATKYQGIVATIKKKEYN-FLDQRKMDFDQDYEEFCKQTNDLHNELRKFM 555
Query: 124 NQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEITAIEDKFTRYRK 183
+ +F ++++ +AL +L KF + + K+ L++ + +I I +T+ +
Sbjct: 556 DVTFAKIQNTNQALRMLKKFERLNIPNL---GIDDKYQLILENYGADIDMISKLYTKQKY 612
Query: 184 NPPLLRNHPPVAGAISWARALFNKMKQPIMKFQKVSELNECEQKKEAFLQYKAFSKIIKE 243
+PPL RN PP+AG I WAR LF++++QP+ FQ+ + + K Y +K++ E
Sbjct: 613 DPPLARNQPPIAGKILWARQLFHRIQQPMQLFQQHPAVLSTAEAKPIIRSYNRMAKVLLE 672
Query: 244 YEDTKYKEWVQ 254
+E ++ W++
Sbjct: 673 FEVLFHRAWLR 683
Score = 58.4 bits (135), Expect = 5e-07
Identities = 29/132 (21%), Positives = 63/132 (47%), Gaps = 1/132 (0%)
Query: 378 NFDKDLFLVIHEAELMEQLGFDVPSNVRDVAMQKSRLFYELEALSKIIAKYNKNASSLSP 437
NFD + ++ E E M Q+G +V + ++ R + ++A+Y + S +
Sbjct: 709 NFDPQILILFRETECMAQMGLEVSPLATSLFQKRDRYKRNFSNMKMMLAEYQRVKSKIPA 768
Query: 438 SETYLMKRHLLDMERHILPGLTRITWTALGINDYIKDITKGENSLQAVYQQLK-MVEKEI 496
+ L+ HL ++ + PGL +TWT+L I Y+++ L+ + ++ ++E I
Sbjct: 769 AIEQLIVPHLAKVDEALQPGLAALTWTSLNIEAYLENTFAKIKDLELLLDRVNDLIEFRI 828
Query: 497 QFLINQLQEFDL 508
++ ++ L
Sbjct: 829 DAILEEMSSTPL 840
Score = 39.5 bits (88), Expect = 0.25
Identities = 41/218 (18%), Positives = 100/218 (45%), Gaps = 20/218 (9%)
Query: 664 LPCPPQRVAEATGNEYYVFSYFEDILRVVAINDITLLIQDTIYRLTQDINSYIQKWHKYQ 723
LP P Q T N Y S ++I+++V++ ++ +I T +++ + + + +Y
Sbjct: 1097 LPIPVQ-----TKNYYKNVSENKEIVKLVSV--LSTIINST----KKEVITSMDCFKRYN 1145
Query: 724 HLWAFDKSLSCEKYIQKHEQIYKYDEKFFFFEDIISDLNTHVKFVDVGASLRMTINMNIK 783
H+W K + + +I + + +++ + +F+++ ++N ++V VG+ T ++
Sbjct: 1146 HIWQKGKEEAIKTFITQSPLLSEFESQILYFQNLEQEINAEPEYVCVGSIALYTADLKFA 1205
Query: 784 GLEDFKLVMATITQVQQMTITAEVKYRG-MQEIFHMLKQHG--INVTDEDLQFAKSLEAS 840
+ K M I + KYR M+ IF ++++ +N +DL + A+
Sbjct: 1206 LTAETKAWMVVIGR------HCNKKYRSEMENIFMLIEEFNKKLNRPIKDLDDIRIAMAA 1259
Query: 841 WGSLYQTSLFRGNTLEQTKEKFSKLNVVEISNFLKELD 878
+ + + + +E ++ LN + +E+D
Sbjct: 1260 LKEIREEQISIDFQVGPIEESYALLNRYGLLIAREEID 1297
>AL391415-3|CAI21588.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 849 bits (2100), Expect = 0.0
Identities = 540/1666 (32%), Positives = 877/1666 (52%), Gaps = 82/1666 (4%)
Query: 782 IKGLEDFKLVMATITQVQQMTITAEVKYRGMQEIFHMLKQHGINVTDEDLQFAKSLEASW 841
I+ L+D + M ++ ++ I ++ ++E + +L + + VT E+ + +L S+
Sbjct: 1318 IRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYSF 1377
Query: 842 GSLYQTSLFRGNTLEQTKEKFSKLNVVE-ISNFLKELDDFVEKFDNEGPATVEDDMDRGL 900
L ++ L Q + KF K N++E + F +++ +F E ++ EGP
Sbjct: 1378 NKLQSKAVSVQEDLVQVQPKF-KSNLLESVEVFREDVINFAEAYELEGPMVPNIPPQEAS 1436
Query: 901 LLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNFNRTKADYSAMDQIYKIYKAQKNA 960
++ + D+L + + EQLF P+ D+ ++T+ + + + ++Y +Y ++
Sbjct: 1437 NRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSS 1496
Query: 961 REVWAKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLMLDLKMKQFKGVVPLMVS 1020
+ + LW +++ + + + +F RKLPK ++ L L ++ F PL+
Sbjct: 1497 ISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEM 1556
Query: 1021 LKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMELHKYQDVAEEIVNHAIKELAIE 1080
+ N+AM++RHW + TG FD+ D F L N+ L K++D E+I AIKE IE
Sbjct: 1557 MTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIE 1616
Query: 1081 RGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVVKLDDDSMSLQSMAASQFIGPF 1140
+ V E W N + S + +GE +I+ ++D M L S+ ++++ PF
Sbjct: 1617 AKLTQVIENWTNQNLSFAAFKGKGELL-LKGTESGEIITLMEDSLMVLGSLLSNRYNAPF 1675
Query: 1141 LTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGGDIRTQLPEEAKKFDDIDRAFRK 1200
+Q W ++LS S+IIEEW+ Q W+YLE +FVGGDI QLP+EAK+F +ID+++ K
Sbjct: 1676 KKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIK 1735
Query: 1201 IMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASSDVTRKQINLSQAIAWADR 1260
IM + NV++CC +G + L Q +S + + +K++ + +D
Sbjct: 1736 IMQRAHENPNVINCC-VGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDP 1794
Query: 1261 ASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYVDHTNRPVAAKMISAEGEIMDF 1320
L ++ ++ Q S DNI + + +R +A +IS EGE +
Sbjct: 1795 VLLEILGQASDSHTIQPHLPAVS------DNINEVTFHAKDYDRIMA--VISREGEKIVL 1846
Query: 1321 RNVVYTEGRVEDWMNLVLVEMRHTNKFITKKAIFYYGKNWKVPRTDWILEYQGMVCLAAN 1380
N V +G VE W+ L L++M+ ++ ++ FY + ++ + V L
Sbjct: 1847 DNSVMAKGPVEIWL-LDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGLLGI 1905
Query: 1381 GVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQLDGLVVKVRQDLSSNDRLKFRTITTID 1440
+ WT ++EE LR K +++ M+ Q+ + L+ L+ + DLS DR+KF T+ TI
Sbjct: 1906 QMLWTHDSEEA-LRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIH 1964
Query: 1441 VHARDIIEGFVRDNITEAAEFEWESQLRFYWLKKDDNLWIRQCTGV-FEYGYEYMGLNGR 1499
VH RDI + V+ +I +FEW Q RFY+ K+D + + T V F Y E++G R
Sbjct: 1965 VHQRDIFDDLVKMHIKSPTDFEWLKQSRFYF-KEDLDQTVVSITDVDFIYQNEFLGCTDR 2023
Query: 1500 LVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDF 1559
LVITPLTDR Y+T+ QAL M + D+ + LG VV NC + MDF
Sbjct: 2024 LVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDF 2083
Query: 1560 RAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLKRFTVNTDVLKP 1619
R +G+I GL Q G+WGCFDEFNRI++ VLSV + Q+ + +A + K+F +
Sbjct: 2084 RGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD----- 2138
Query: 1620 SQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTELPESVKALFRPVVCILPDLEMI 1679
G + ++ + GIF+TMNPGYAGR ELPE++K FR V ++PD ++I
Sbjct: 2139 -------------GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQII 2185
Query: 1680 CQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTAVLRMAGKLRRDSPG 1739
++ L S GFL +LA+K VLYK+ EQL+KQ HYD+GLR + +VLR G +R P
Sbjct: 2186 MRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPE 2245
Query: 1740 LSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEKDG 1799
SE+ ++MR LRDMN K V ED PLFL LI DLFPGL+ Y E AV ++ +G
Sbjct: 2246 DSELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEG 2305
Query: 1800 YVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNLGLPTKLTVVNPK 1859
+ P K+VQLYET + RH M +GP+G GKT ++ L+KAQT G P + +NPK
Sbjct: 2306 LINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQTECGRPHREMRMNPK 2365
Query: 1860 ACSVIELYGILDPVTRDWTDGLYSKIFREMNRPAEKNERRYSLFDGDVDALWIENMNSVM 1919
A + +++G LD T DWTDG++S ++R+ + A+K E + + DG VDA+WIEN+NSV+
Sbjct: 2366 AITAPQMFGRLDTATNDWTDGIFSTLWRKTLK-AKKGENIFLILDGPVDAIWIENLNSVL 2424
Query: 1920 DDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGYEPYWERWL 1979
DDNK LTLANG+RI +AP C LLFEV ++ ASPATVSR GMV++ L + P + WL
Sbjct: 2425 DDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWL 2484
Query: 1980 STRSNEEEREQLSGLFEHYVPGAINYIVFGMFGLQQQTPLKTIVPQTPLNLVMQLCYMIS 2039
R+ +E L+ L+E Y+ + P ++ N ++Q ++
Sbjct: 2485 KKRTAQEAAVFLT-LYEKVFEDTYTYMKLNL------NPKMQLL---ECNYIVQSLNLLE 2534
Query: 2040 GLLPNNEDTNMEIDKTVVECVFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVEDNPE 2099
GL+P+ E+ + + + + +F+ + SLGA + R + ++++ E
Sbjct: 2535 GLIPSKEEGGVSCVEHLHK-LFVFGLMWSLGALLELESREKLEAFLRQ----------HE 2583
Query: 2100 KKATTKHFPMGF-PTLYDYCLELTTKLWEAWDWLVPEYEHDRDM--KFPAILVPTVDTLR 2156
K P G T+Y++ + WE W+ + Y + D ++ +ILVP VD +R
Sbjct: 2584 SKLDLPEIPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIR 2642
Query: 2157 LTWLIKIMESIIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMP 2216
+LI ++I +Q T Q ++V+ K + P V + P
Sbjct: 2643 TNFLI---DTIAKQHKAVLLTGE---QGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEP 2696
Query: 2217 ------IVSHNNQCVPSLCST---RVQTL----LSHPLVDTYGTQQPIALLKLLFERKGF 2263
I S+ ++ + S R T+ ++ P+++ +G Q +++ + E +G
Sbjct: 2697 MMFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGM 2756
Query: 2264 YDRGKDLNWKNLKDIGFLAAMGKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSIL 2323
Y K ++ + D+ +AAM GGGRND+ R F+V+N PS ++ I+ I
Sbjct: 2757 YSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIG 2816
Query: 2324 KGHFE---IFPEEIQGIVEKIVQMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMC 2380
G+F+ F +I ++ +V + L++ V++ PTP+KFHYIFNLRDLSRI GM
Sbjct: 2817 CGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGML 2876
Query: 2381 LTHANYFSEKRTVVRCWRNEFTRVICDRLINQQDNELMRGHIQEHV 2426
A + T++ +++E +RVI DR I +D + H+ V
Sbjct: 2877 TIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAV 2922
Score = 652 bits (1612), Expect = 0.0
Identities = 366/1107 (33%), Positives = 591/1107 (53%), Gaps = 26/1107 (2%)
Query: 2682 AKCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKI-PEEFRPIIVEHVVHVHMSV 2740
A+ FPGL++ T+DW WP++AL+AVA+ FL+D + E + +VE + H V
Sbjct: 3166 ARSLKFPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMV 3225
Query: 2741 ARYSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQ 2800
+ + R RR +VTPK Y+ F+ Y + EK FI Q ER+ GL K+ EA+
Sbjct: 3226 SESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASES 3285
Query: 2801 LEDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVE 2860
+ L+ LAV++ +A + + + +L E++ + + + + I E
Sbjct: 3286 VAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSE 3345
Query: 2861 KXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVII--RGIKD 2918
K NDI +R A PP + + +CV+++ + I
Sbjct: 3346 KVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDP 3405
Query: 2919 V-----------SWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLDTM 2966
V SW + +M+ FL +LQ+ D I + V+ ++ + ++
Sbjct: 3406 VTMDPEKSCCKPSWGESLKLMSATGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESA 3465
Query: 2967 QQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQK 3026
+++ GLL + A+ + + A L +D Q
Sbjct: 3466 KKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQA 3525
Query: 3027 TLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSR 3086
LD + +++ AM + +L + D +++ AA L+ GLS E+ RWT+ + +R
Sbjct: 3526 ELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINR 3585
Query: 3087 LIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSG 3146
L+G+ LL T FLSY GPF+ FR ++ + W ++ R IP T + L + +
Sbjct: 3586 LVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARKIPFTENLNLISMLVDPPTIGE 3645
Query: 3147 WNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLR 3206
W +GLP D+LS+QNGI+ T+A+R+PL IDPQTQ TWIK KE +N+L+V S N F
Sbjct: 3646 WGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRT 3705
Query: 3207 QLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTF-VMLGSTEVDYDPNFRMYL 3265
LE ++ G P+L +D++E +DP +DNVLEKN ++SG TF V +G E D F++Y+
Sbjct: 3706 HLEDSLSLGRPLLIEDIHEELDPALDNVLEKNF-IKSGTTFKVKVGDKECDIMDTFKLYI 3764
Query: 3266 TTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANK 3325
TTKL NP F P AK VI++TVT++GLE+QLL V+ E+ +LE +R L+ + + NK
Sbjct: 3765 TTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNK 3824
Query: 3326 SLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRD 3385
+ LED+LL +L+ + G+++D+ L+ L TK AAEV EKL +A T I ++
Sbjct: 3825 RKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQE 3884
Query: 3386 GYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDM 3445
+RP A RGSIL+F++++M+ VN MYQ SL+ +L +F S+ ++ + + KR+ NII+
Sbjct: 3885 EFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEY 3944
Query: 3446 LTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLE-KSARSSP 3504
LT V+ Y G++E HK LF M +K++ V + IKG +L+ K+ P
Sbjct: 3945 LTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKP 4004
Query: 3505 APWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLK 3564
W+ W ++++LS P FA + + I++ + W+ WFD D PE IP+ Y + L
Sbjct: 4005 YRWILDMTWLNLVELSK-LPQ-FAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLD 4062
Query: 3565 PFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPG 3624
L+L+R + DR YI ++ E+Y P +++L+ E++ TP++ LS G
Sbjct: 4063 TCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMG 4122
Query: 3625 SDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFL 3684
SDPT + LA + + + +S+GQGQE A L++ ++ G W++LQNCHL + F+
Sbjct: 4123 SDPTNQIDALAKKLKL---ECRTISMGQGQEVHARKLIQMSMQQGGWVLLQNCHLGLEFM 4179
Query: 3685 RELEKQLELMTKPHPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLNLRNTYFKMR 3741
EL + L +R+W+TT+P FPI +LQ SLK EPP G++ L+ T+ +
Sbjct: 4180 EELLETLITTEASDDSFRVWITTEPHDRFPITLLQTSLKFTNEPPQGVRAGLKRTFAGIN 4239
Query: 3742 ARALEECPHPQFKKLVYVLAFFHAVVQ 3768
L+ P +K ++Y +AF H+ VQ
Sbjct: 4240 QDLLDISNLPMWKPMLYTVAFLHSTVQ 4266
Score = 192 bits (469), Expect = 2e-47
Identities = 128/408 (31%), Positives = 201/408 (49%), Gaps = 17/408 (4%)
Query: 3745 LEECPHPQFKKLVYVLAFFHAVVQVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFH 3804
L+EC KK V + + +V YGG + + E +F+ F
Sbjct: 4298 LDEC---DIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMFEP--SFC 4352
Query: 3805 FYKDYAFDYVIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIE 3864
FY Y IP D+Y ++I +LP + PEVFGLHPNA+I Y S + +
Sbjct: 4353 FYTGYK----IPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQSNTASAVLETITN 4408
Query: 3865 LQPQTSEAGGAMSREDFIDNIAVDVLSKLPTLYEIWRVRKQ-FEM-NITPTLVVLLQELE 3922
+QP+ S G +RE + ++ D+LSKLP Y V+ + +M ++ + L QE++
Sbjct: 4409 IQPKESGGGVGETREAIVYRLSEDMLSKLPPDYIPHEVKSRLIKMGHLNSMNIFLRQEID 4468
Query: 3923 RFNRLISRMGSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGW 3982
R R+IS + S+LS L+ A+ G I M L + ++++ ++PQ+W+ ++ LG W
Sbjct: 4469 RMQRVISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQLWKRVS-WDSSTLGFW 4527
Query: 3983 MDHFIARTKQYTDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYT-WPLDRSTQFTKV 4041
+ R Q++ W P V W++G P+ +L A Q R + W LD T +V
Sbjct: 4528 FTELLERNAQFSTWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDTVTIHNEV 4587
Query: 4042 TSWVSADEIEERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHK 4101
+ +EI P G Y+ GLY++GA WD G L S PKVL T+LP+++I I
Sbjct: 4588 LR-QTKEEITSPPGEGVYIYGLYMDGAAWDRRNGKLMESTPKVLFTQLPVLHIFAINSTA 4646
Query: 4102 LKLQNTLRTPVYTTSQRRNAMGVGLVFESDLWTTEHCSHWILQGVCLI 4149
K P+Y +R + + +V+ L T HWIL+GV L+
Sbjct: 4647 PKDPKLYVCPIYKKPRRTDLTFITVVY---LRTVLSPDHWILRGVALL 4691
Score = 109 bits (262), Expect = 2e-22
Identities = 55/154 (35%), Positives = 85/154 (55%), Gaps = 2/154 (1%)
Query: 2515 RYYEDLLDYEAIYFLFQEILDEYNE--RNAKMSIVLFEDCLEHLTRTHRILRMDRGNAMX 2572
+ YE + ++ + Q ++NE R + +V F+D + HL + RI+R GNA+
Sbjct: 2964 KIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALL 3023
Query: 2573 XXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMYLQLGVDNKKTVFLFT 2632
+LA+F AG ++F+IT+TR+YN DD+K +Y G D K F+FT
Sbjct: 3024 VGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITFIFT 3083
Query: 2633 AAQILEEGFLEFINNILMIGMIPALFGDDEKDSI 2666
++I +E FLE++NN+L G I LF DE D I
Sbjct: 3084 DSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEI 3117
Score = 96.7 bits (230), Expect = 2e-18
Identities = 74/334 (22%), Positives = 156/334 (46%), Gaps = 22/334 (6%)
Query: 54 ERIFGLELKSIISDPT--QIDDVRKRVKNLVYPIRTVDFSVFVFDNKENWDVIMGDFWNE 111
E I ++ S +S+ T ID + + +N+ ++ + + + + +D DF +
Sbjct: 579 EMITVVQTYSTLSNSTIEGIDIMAIKFRNIYQGVKKKQYDI-LDPRRTEFDTDFLDFMTK 637
Query: 112 VRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEI 171
+ LE + + ++N SFG + SS++AL +L +F + + + +++ + +++ ++ E+
Sbjct: 638 INGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLNI-PCLGLEINHTIERILQYYVAEL 696
Query: 172 TAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMKQPIMKFQKVSELNECEQKKEAF 231
A + + + +PPL RN PP+AG I W R L+ ++ +PI F K S++ K
Sbjct: 697 DATKKLYHSQKDDPPLARNMPPIAGKILWVRQLYRRISEPINYFFKNSDILSSPDGKAVI 756
Query: 232 LQYKAFSKIIKEYEDTKYKEWVQDASLFCDNMMKKNILKVVFKKEDDP----VPQKARGM 287
QY S ++ E+E + W+++ S + + +F + + V + +
Sbjct: 757 RQYNKISYVLVEFEVVYHTAWIREIS-----QLHYALQATLFVRHPETGKLLVNFDPKIL 811
Query: 288 QLTAAGRAHVAKK-KASNTSLKPLDIVNKEIADKRRRDKAL-----MLMRIPGQHYENVR 341
++ + + K + + L + +K ADK L + +P + N+
Sbjct: 812 EVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPSV-FVNLM 870
Query: 342 SP--SSVSLLAKEGLTDVTWRDLTVHKLIQEYNL 373
+P V + ++GLT +TW LT+ QE L
Sbjct: 871 TPKMKKVESVLRQGLTVLTWSSLTLESFFQEVEL 904
Score = 42.7 bits (96), Expect = 0.027
Identities = 22/98 (22%), Positives = 48/98 (48%)
Query: 378 NFDKDLFLVIHEAELMEQLGFDVPSNVRDVAMQKSRLFYELEALSKIIAKYNKNASSLSP 437
NFD + V+ E + M ++ DVP + + +S+L + L ++ Y++ +
Sbjct: 805 NFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPS 864
Query: 438 SETYLMKRHLLDMERHILPGLTRITWTALGINDYIKDI 475
LM + +E + GLT +TW++L + + +++
Sbjct: 865 VFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQEV 902
>AL391415-2|CAI21587.1| 4176|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4176
Score = 849 bits (2100), Expect = 0.0
Identities = 540/1666 (32%), Positives = 877/1666 (52%), Gaps = 82/1666 (4%)
Query: 782 IKGLEDFKLVMATITQVQQMTITAEVKYRGMQEIFHMLKQHGINVTDEDLQFAKSLEASW 841
I+ L+D + M ++ ++ I ++ ++E + +L + + VT E+ + +L S+
Sbjct: 1318 IRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYSF 1377
Query: 842 GSLYQTSLFRGNTLEQTKEKFSKLNVVE-ISNFLKELDDFVEKFDNEGPATVEDDMDRGL 900
L ++ L Q + KF K N++E + F +++ +F E ++ EGP
Sbjct: 1378 NKLQSKAVSVQEDLVQVQPKF-KSNLLESVEVFREDVINFAEAYELEGPMVPNIPPQEAS 1436
Query: 901 LLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNFNRTKADYSAMDQIYKIYKAQKNA 960
++ + D+L + + EQLF P+ D+ ++T+ + + + ++Y +Y ++
Sbjct: 1437 NRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSS 1496
Query: 961 REVWAKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLMLDLKMKQFKGVVPLMVS 1020
+ + LW +++ + + + +F RKLPK ++ L L ++ F PL+
Sbjct: 1497 ISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEM 1556
Query: 1021 LKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMELHKYQDVAEEIVNHAIKELAIE 1080
+ N+AM++RHW + TG FD+ D F L N+ L K++D E+I AIKE IE
Sbjct: 1557 MTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIE 1616
Query: 1081 RGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVVKLDDDSMSLQSMAASQFIGPF 1140
+ V E W N + S + +GE +I+ ++D M L S+ ++++ PF
Sbjct: 1617 AKLTQVIENWTNQNLSFAAFKGKGELL-LKGTESGEIITLMEDSLMVLGSLLSNRYNAPF 1675
Query: 1141 LTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGGDIRTQLPEEAKKFDDIDRAFRK 1200
+Q W ++LS S+IIEEW+ Q W+YLE +FVGGDI QLP+EAK+F +ID+++ K
Sbjct: 1676 KKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIK 1735
Query: 1201 IMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASSDVTRKQINLSQAIAWADR 1260
IM + NV++CC +G + L Q +S + + +K++ + +D
Sbjct: 1736 IMQRAHENPNVINCC-VGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDP 1794
Query: 1261 ASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYVDHTNRPVAAKMISAEGEIMDF 1320
L ++ ++ Q S DNI + + +R +A +IS EGE +
Sbjct: 1795 VLLEILGQASDSHTIQPHLPAVS------DNINEVTFHAKDYDRIMA--VISREGEKIVL 1846
Query: 1321 RNVVYTEGRVEDWMNLVLVEMRHTNKFITKKAIFYYGKNWKVPRTDWILEYQGMVCLAAN 1380
N V +G VE W+ L L++M+ ++ ++ FY + ++ + V L
Sbjct: 1847 DNSVMAKGPVEIWL-LDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGLLGI 1905
Query: 1381 GVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQLDGLVVKVRQDLSSNDRLKFRTITTID 1440
+ WT ++EE LR K +++ M+ Q+ + L+ L+ + DLS DR+KF T+ TI
Sbjct: 1906 QMLWTHDSEEA-LRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIH 1964
Query: 1441 VHARDIIEGFVRDNITEAAEFEWESQLRFYWLKKDDNLWIRQCTGV-FEYGYEYMGLNGR 1499
VH RDI + V+ +I +FEW Q RFY+ K+D + + T V F Y E++G R
Sbjct: 1965 VHQRDIFDDLVKMHIKSPTDFEWLKQSRFYF-KEDLDQTVVSITDVDFIYQNEFLGCTDR 2023
Query: 1500 LVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDF 1559
LVITPLTDR Y+T+ QAL M + D+ + LG VV NC + MDF
Sbjct: 2024 LVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDF 2083
Query: 1560 RAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLKRFTVNTDVLKP 1619
R +G+I GL Q G+WGCFDEFNRI++ VLSV + Q+ + +A + K+F +
Sbjct: 2084 RGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD----- 2138
Query: 1620 SQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTELPESVKALFRPVVCILPDLEMI 1679
G + ++ + GIF+TMNPGYAGR ELPE++K FR V ++PD ++I
Sbjct: 2139 -------------GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQII 2185
Query: 1680 CQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTAVLRMAGKLRRDSPG 1739
++ L S GFL +LA+K VLYK+ EQL+KQ HYD+GLR + +VLR G +R P
Sbjct: 2186 MRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPE 2245
Query: 1740 LSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEKDG 1799
SE+ ++MR LRDMN K V ED PLFL LI DLFPGL+ Y E AV ++ +G
Sbjct: 2246 DSELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEG 2305
Query: 1800 YVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNLGLPTKLTVVNPK 1859
+ P K+VQLYET + RH M +GP+G GKT ++ L+KAQT G P + +NPK
Sbjct: 2306 LINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQTECGRPHREMRMNPK 2365
Query: 1860 ACSVIELYGILDPVTRDWTDGLYSKIFREMNRPAEKNERRYSLFDGDVDALWIENMNSVM 1919
A + +++G LD T DWTDG++S ++R+ + A+K E + + DG VDA+WIEN+NSV+
Sbjct: 2366 AITAPQMFGRLDTATNDWTDGIFSTLWRKTLK-AKKGENIFLILDGPVDAIWIENLNSVL 2424
Query: 1920 DDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGYEPYWERWL 1979
DDNK LTLANG+RI +AP C LLFEV ++ ASPATVSR GMV++ L + P + WL
Sbjct: 2425 DDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWL 2484
Query: 1980 STRSNEEEREQLSGLFEHYVPGAINYIVFGMFGLQQQTPLKTIVPQTPLNLVMQLCYMIS 2039
R+ +E L+ L+E Y+ + P ++ N ++Q ++
Sbjct: 2485 KKRTAQEAAVFLT-LYEKVFEDTYTYMKLNL------NPKMQLL---ECNYIVQSLNLLE 2534
Query: 2040 GLLPNNEDTNMEIDKTVVECVFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVEDNPE 2099
GL+P+ E+ + + + + +F+ + SLGA + R + ++++ E
Sbjct: 2535 GLIPSKEEGGVSCVEHLHK-LFVFGLMWSLGALLELESREKLEAFLRQ----------HE 2583
Query: 2100 KKATTKHFPMGF-PTLYDYCLELTTKLWEAWDWLVPEYEHDRDM--KFPAILVPTVDTLR 2156
K P G T+Y++ + WE W+ + Y + D ++ +ILVP VD +R
Sbjct: 2584 SKLDLPEIPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIR 2642
Query: 2157 LTWLIKIMESIIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMP 2216
+LI ++I +Q T Q ++V+ K + P V + P
Sbjct: 2643 TNFLI---DTIAKQHKAVLLTGE---QGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEP 2696
Query: 2217 ------IVSHNNQCVPSLCST---RVQTL----LSHPLVDTYGTQQPIALLKLLFERKGF 2263
I S+ ++ + S R T+ ++ P+++ +G Q +++ + E +G
Sbjct: 2697 MMFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGM 2756
Query: 2264 YDRGKDLNWKNLKDIGFLAAMGKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSIL 2323
Y K ++ + D+ +AAM GGGRND+ R F+V+N PS ++ I+ I
Sbjct: 2757 YSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIG 2816
Query: 2324 KGHFE---IFPEEIQGIVEKIVQMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMC 2380
G+F+ F +I ++ +V + L++ V++ PTP+KFHYIFNLRDLSRI GM
Sbjct: 2817 CGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGML 2876
Query: 2381 LTHANYFSEKRTVVRCWRNEFTRVICDRLINQQDNELMRGHIQEHV 2426
A + T++ +++E +RVI DR I +D + H+ V
Sbjct: 2877 TIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAV 2922
Score = 572 bits (1412), Expect = e-162
Identities = 326/999 (32%), Positives = 528/999 (52%), Gaps = 23/999 (2%)
Query: 2682 AKCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKI-PEEFRPIIVEHVVHVHMSV 2740
A+ FPGL++ T+DW WP++AL+AVA+ FL+D + E + +VE + H V
Sbjct: 3166 ARSLKFPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMV 3225
Query: 2741 ARYSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQ 2800
+ + R RR +VTPK Y+ F+ Y + EK FI Q ER+ GL K+ EA+
Sbjct: 3226 SESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASES 3285
Query: 2801 LEDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVE 2860
+ L+ LAV++ +A + + + +L E++ + + + + I E
Sbjct: 3286 VAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSE 3345
Query: 2861 KXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVII--RGIKD 2918
K NDI +R A PP + + +CV+++ + I
Sbjct: 3346 KVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDP 3405
Query: 2919 V-----------SWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLDTM 2966
V SW + +M+ FL +LQ+ D I + V+ ++ + ++
Sbjct: 3406 VTMDPEKSCCKPSWGESLKLMSATGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESA 3465
Query: 2967 QQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQK 3026
+++ GLL + A+ + + A L +D Q
Sbjct: 3466 KKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQA 3525
Query: 3027 TLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSR 3086
LD + +++ AM + +L + D +++ AA L+ GLS E+ RWT+ + +R
Sbjct: 3526 ELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINR 3585
Query: 3087 LIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSG 3146
L+G+ LL T FLSY GPF+ FR ++ + W ++ R IP T + L + +
Sbjct: 3586 LVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARKIPFTENLNLISMLVDPPTIGE 3645
Query: 3147 WNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLR 3206
W +GLP D+LS+QNGI+ T+A+R+PL IDPQTQ TWIK KE +N+L+V S N F
Sbjct: 3646 WGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRT 3705
Query: 3207 QLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTF-VMLGSTEVDYDPNFRMYL 3265
LE ++ G P+L +D++E +DP +DNVLEKN ++SG TF V +G E D F++Y+
Sbjct: 3706 HLEDSLSLGRPLLIEDIHEELDPALDNVLEKNF-IKSGTTFKVKVGDKECDIMDTFKLYI 3764
Query: 3266 TTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANK 3325
TTKL NP F P AK VI++TVT++GLE+QLL V+ E+ +LE +R L+ + + NK
Sbjct: 3765 TTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNK 3824
Query: 3326 SLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRD 3385
+ LED+LL +L+ + G+++D+ L+ L TK AAEV EKL +A T I ++
Sbjct: 3825 RKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQE 3884
Query: 3386 GYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDM 3445
+RP A RGSIL+F++++M+ VN MYQ SL+ +L +F S+ ++ + + KR+ NII+
Sbjct: 3885 EFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEY 3944
Query: 3446 LTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLE-KSARSSP 3504
LT V+ Y G++E HK LF M +K++ V + IKG +L+ K+ P
Sbjct: 3945 LTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKP 4004
Query: 3505 APWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLK 3564
W+ W ++++LS P FA + + I++ + W+ WFD D PE IP+ Y + L
Sbjct: 4005 YRWILDMTWLNLVELSK-LPQ-FAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLD 4062
Query: 3565 PFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPG 3624
L+L+R + DR YI ++ E+Y P +++L+ E++ TP++ LS G
Sbjct: 4063 TCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMG 4122
Query: 3625 SDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLE 3663
SDPT + LA + + + +S+GQGQE A L++
Sbjct: 4123 SDPTNQIDALAKKLKL---ECRTISMGQGQEVHARKLIQ 4158
Score = 109 bits (262), Expect = 2e-22
Identities = 55/154 (35%), Positives = 85/154 (55%), Gaps = 2/154 (1%)
Query: 2515 RYYEDLLDYEAIYFLFQEILDEYNE--RNAKMSIVLFEDCLEHLTRTHRILRMDRGNAMX 2572
+ YE + ++ + Q ++NE R + +V F+D + HL + RI+R GNA+
Sbjct: 2964 KIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALL 3023
Query: 2573 XXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMYLQLGVDNKKTVFLFT 2632
+LA+F AG ++F+IT+TR+YN DD+K +Y G D K F+FT
Sbjct: 3024 VGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITFIFT 3083
Query: 2633 AAQILEEGFLEFINNILMIGMIPALFGDDEKDSI 2666
++I +E FLE++NN+L G I LF DE D I
Sbjct: 3084 DSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEI 3117
Score = 96.7 bits (230), Expect = 2e-18
Identities = 74/334 (22%), Positives = 156/334 (46%), Gaps = 22/334 (6%)
Query: 54 ERIFGLELKSIISDPT--QIDDVRKRVKNLVYPIRTVDFSVFVFDNKENWDVIMGDFWNE 111
E I ++ S +S+ T ID + + +N+ ++ + + + + +D DF +
Sbjct: 579 EMITVVQTYSTLSNSTIEGIDIMAIKFRNIYQGVKKKQYDI-LDPRRTEFDTDFLDFMTK 637
Query: 112 VRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEI 171
+ LE + + ++N SFG + SS++AL +L +F + + + +++ + +++ ++ E+
Sbjct: 638 INGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLNI-PCLGLEINHTIERILQYYVAEL 696
Query: 172 TAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMKQPIMKFQKVSELNECEQKKEAF 231
A + + + +PPL RN PP+AG I W R L+ ++ +PI F K S++ K
Sbjct: 697 DATKKLYHSQKDDPPLARNMPPIAGKILWVRQLYRRISEPINYFFKNSDILSSPDGKAVI 756
Query: 232 LQYKAFSKIIKEYEDTKYKEWVQDASLFCDNMMKKNILKVVFKKEDDP----VPQKARGM 287
QY S ++ E+E + W+++ S + + +F + + V + +
Sbjct: 757 RQYNKISYVLVEFEVVYHTAWIREIS-----QLHYALQATLFVRHPETGKLLVNFDPKIL 811
Query: 288 QLTAAGRAHVAKK-KASNTSLKPLDIVNKEIADKRRRDKAL-----MLMRIPGQHYENVR 341
++ + + K + + L + +K ADK L + +P + N+
Sbjct: 812 EVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPSV-FVNLM 870
Query: 342 SP--SSVSLLAKEGLTDVTWRDLTVHKLIQEYNL 373
+P V + ++GLT +TW LT+ QE L
Sbjct: 871 TPKMKKVESVLRQGLTVLTWSSLTLESFFQEVEL 904
Score = 42.7 bits (96), Expect = 0.027
Identities = 22/98 (22%), Positives = 48/98 (48%)
Query: 378 NFDKDLFLVIHEAELMEQLGFDVPSNVRDVAMQKSRLFYELEALSKIIAKYNKNASSLSP 437
NFD + V+ E + M ++ DVP + + +S+L + L ++ Y++ +
Sbjct: 805 NFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPS 864
Query: 438 SETYLMKRHLLDMERHILPGLTRITWTALGINDYIKDI 475
LM + +E + GLT +TW++L + + +++
Sbjct: 865 VFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQEV 902
>AL353700-3|CAI20294.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 849 bits (2100), Expect = 0.0
Identities = 540/1666 (32%), Positives = 877/1666 (52%), Gaps = 82/1666 (4%)
Query: 782 IKGLEDFKLVMATITQVQQMTITAEVKYRGMQEIFHMLKQHGINVTDEDLQFAKSLEASW 841
I+ L+D + M ++ ++ I ++ ++E + +L + + VT E+ + +L S+
Sbjct: 1318 IRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYSF 1377
Query: 842 GSLYQTSLFRGNTLEQTKEKFSKLNVVE-ISNFLKELDDFVEKFDNEGPATVEDDMDRGL 900
L ++ L Q + KF K N++E + F +++ +F E ++ EGP
Sbjct: 1378 NKLQSKAVSVQEDLVQVQPKF-KSNLLESVEVFREDVINFAEAYELEGPMVPNIPPQEAS 1436
Query: 901 LLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNFNRTKADYSAMDQIYKIYKAQKNA 960
++ + D+L + + EQLF P+ D+ ++T+ + + + ++Y +Y ++
Sbjct: 1437 NRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSS 1496
Query: 961 REVWAKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLMLDLKMKQFKGVVPLMVS 1020
+ + LW +++ + + + +F RKLPK ++ L L ++ F PL+
Sbjct: 1497 ISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEM 1556
Query: 1021 LKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMELHKYQDVAEEIVNHAIKELAIE 1080
+ N+AM++RHW + TG FD+ D F L N+ L K++D E+I AIKE IE
Sbjct: 1557 MTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIE 1616
Query: 1081 RGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVVKLDDDSMSLQSMAASQFIGPF 1140
+ V E W N + S + +GE +I+ ++D M L S+ ++++ PF
Sbjct: 1617 AKLTQVIENWTNQNLSFAAFKGKGELL-LKGTESGEIITLMEDSLMVLGSLLSNRYNAPF 1675
Query: 1141 LTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGGDIRTQLPEEAKKFDDIDRAFRK 1200
+Q W ++LS S+IIEEW+ Q W+YLE +FVGGDI QLP+EAK+F +ID+++ K
Sbjct: 1676 KKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIK 1735
Query: 1201 IMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASSDVTRKQINLSQAIAWADR 1260
IM + NV++CC +G + L Q +S + + +K++ + +D
Sbjct: 1736 IMQRAHENPNVINCC-VGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDP 1794
Query: 1261 ASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYVDHTNRPVAAKMISAEGEIMDF 1320
L ++ ++ Q S DNI + + +R +A +IS EGE +
Sbjct: 1795 VLLEILGQASDSHTIQPHLPAVS------DNINEVTFHAKDYDRIMA--VISREGEKIVL 1846
Query: 1321 RNVVYTEGRVEDWMNLVLVEMRHTNKFITKKAIFYYGKNWKVPRTDWILEYQGMVCLAAN 1380
N V +G VE W+ L L++M+ ++ ++ FY + ++ + V L
Sbjct: 1847 DNSVMAKGPVEIWL-LDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGLLGI 1905
Query: 1381 GVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQLDGLVVKVRQDLSSNDRLKFRTITTID 1440
+ WT ++EE LR K +++ M+ Q+ + L+ L+ + DLS DR+KF T+ TI
Sbjct: 1906 QMLWTHDSEEA-LRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIH 1964
Query: 1441 VHARDIIEGFVRDNITEAAEFEWESQLRFYWLKKDDNLWIRQCTGV-FEYGYEYMGLNGR 1499
VH RDI + V+ +I +FEW Q RFY+ K+D + + T V F Y E++G R
Sbjct: 1965 VHQRDIFDDLVKMHIKSPTDFEWLKQSRFYF-KEDLDQTVVSITDVDFIYQNEFLGCTDR 2023
Query: 1500 LVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDF 1559
LVITPLTDR Y+T+ QAL M + D+ + LG VV NC + MDF
Sbjct: 2024 LVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDF 2083
Query: 1560 RAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLKRFTVNTDVLKP 1619
R +G+I GL Q G+WGCFDEFNRI++ VLSV + Q+ + +A + K+F +
Sbjct: 2084 RGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD----- 2138
Query: 1620 SQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTELPESVKALFRPVVCILPDLEMI 1679
G + ++ + GIF+TMNPGYAGR ELPE++K FR V ++PD ++I
Sbjct: 2139 -------------GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQII 2185
Query: 1680 CQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTAVLRMAGKLRRDSPG 1739
++ L S GFL +LA+K VLYK+ EQL+KQ HYD+GLR + +VLR G +R P
Sbjct: 2186 MRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPE 2245
Query: 1740 LSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEKDG 1799
SE+ ++MR LRDMN K V ED PLFL LI DLFPGL+ Y E AV ++ +G
Sbjct: 2246 DSELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEG 2305
Query: 1800 YVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNLGLPTKLTVVNPK 1859
+ P K+VQLYET + RH M +GP+G GKT ++ L+KAQT G P + +NPK
Sbjct: 2306 LINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQTECGRPHREMRMNPK 2365
Query: 1860 ACSVIELYGILDPVTRDWTDGLYSKIFREMNRPAEKNERRYSLFDGDVDALWIENMNSVM 1919
A + +++G LD T DWTDG++S ++R+ + A+K E + + DG VDA+WIEN+NSV+
Sbjct: 2366 AITAPQMFGRLDTATNDWTDGIFSTLWRKTLK-AKKGENIFLILDGPVDAIWIENLNSVL 2424
Query: 1920 DDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGYEPYWERWL 1979
DDNK LTLANG+RI +AP C LLFEV ++ ASPATVSR GMV++ L + P + WL
Sbjct: 2425 DDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWL 2484
Query: 1980 STRSNEEEREQLSGLFEHYVPGAINYIVFGMFGLQQQTPLKTIVPQTPLNLVMQLCYMIS 2039
R+ +E L+ L+E Y+ + P ++ N ++Q ++
Sbjct: 2485 KKRTAQEAAVFLT-LYEKVFEDTYTYMKLNL------NPKMQLL---ECNYIVQSLNLLE 2534
Query: 2040 GLLPNNEDTNMEIDKTVVECVFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVEDNPE 2099
GL+P+ E+ + + + + +F+ + SLGA + R + ++++ E
Sbjct: 2535 GLIPSKEEGGVSCVEHLHK-LFVFGLMWSLGALLELESREKLEAFLRQ----------HE 2583
Query: 2100 KKATTKHFPMGF-PTLYDYCLELTTKLWEAWDWLVPEYEHDRDM--KFPAILVPTVDTLR 2156
K P G T+Y++ + WE W+ + Y + D ++ +ILVP VD +R
Sbjct: 2584 SKLDLPEIPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIR 2642
Query: 2157 LTWLIKIMESIIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMP 2216
+LI ++I +Q T Q ++V+ K + P V + P
Sbjct: 2643 TNFLI---DTIAKQHKAVLLTGE---QGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEP 2696
Query: 2217 ------IVSHNNQCVPSLCST---RVQTL----LSHPLVDTYGTQQPIALLKLLFERKGF 2263
I S+ ++ + S R T+ ++ P+++ +G Q +++ + E +G
Sbjct: 2697 MMFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGM 2756
Query: 2264 YDRGKDLNWKNLKDIGFLAAMGKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSIL 2323
Y K ++ + D+ +AAM GGGRND+ R F+V+N PS ++ I+ I
Sbjct: 2757 YSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIG 2816
Query: 2324 KGHFE---IFPEEIQGIVEKIVQMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMC 2380
G+F+ F +I ++ +V + L++ V++ PTP+KFHYIFNLRDLSRI GM
Sbjct: 2817 CGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGML 2876
Query: 2381 LTHANYFSEKRTVVRCWRNEFTRVICDRLINQQDNELMRGHIQEHV 2426
A + T++ +++E +RVI DR I +D + H+ V
Sbjct: 2877 TIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAV 2922
Score = 652 bits (1612), Expect = 0.0
Identities = 366/1107 (33%), Positives = 591/1107 (53%), Gaps = 26/1107 (2%)
Query: 2682 AKCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKI-PEEFRPIIVEHVVHVHMSV 2740
A+ FPGL++ T+DW WP++AL+AVA+ FL+D + E + +VE + H V
Sbjct: 3166 ARSLKFPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMV 3225
Query: 2741 ARYSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQ 2800
+ + R RR +VTPK Y+ F+ Y + EK FI Q ER+ GL K+ EA+
Sbjct: 3226 SESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASES 3285
Query: 2801 LEDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVE 2860
+ L+ LAV++ +A + + + +L E++ + + + + I E
Sbjct: 3286 VAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSE 3345
Query: 2861 KXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVII--RGIKD 2918
K NDI +R A PP + + +CV+++ + I
Sbjct: 3346 KVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDP 3405
Query: 2919 V-----------SWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLDTM 2966
V SW + +M+ FL +LQ+ D I + V+ ++ + ++
Sbjct: 3406 VTMDPEKSCCKPSWGESLKLMSATGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESA 3465
Query: 2967 QQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQK 3026
+++ GLL + A+ + + A L +D Q
Sbjct: 3466 KKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQA 3525
Query: 3027 TLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSR 3086
LD + +++ AM + +L + D +++ AA L+ GLS E+ RWT+ + +R
Sbjct: 3526 ELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINR 3585
Query: 3087 LIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSG 3146
L+G+ LL T FLSY GPF+ FR ++ + W ++ R IP T + L + +
Sbjct: 3586 LVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARKIPFTENLNLISMLVDPPTIGE 3645
Query: 3147 WNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLR 3206
W +GLP D+LS+QNGI+ T+A+R+PL IDPQTQ TWIK KE +N+L+V S N F
Sbjct: 3646 WGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRT 3705
Query: 3207 QLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTF-VMLGSTEVDYDPNFRMYL 3265
LE ++ G P+L +D++E +DP +DNVLEKN ++SG TF V +G E D F++Y+
Sbjct: 3706 HLEDSLSLGRPLLIEDIHEELDPALDNVLEKNF-IKSGTTFKVKVGDKECDIMDTFKLYI 3764
Query: 3266 TTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANK 3325
TTKL NP F P AK VI++TVT++GLE+QLL V+ E+ +LE +R L+ + + NK
Sbjct: 3765 TTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNK 3824
Query: 3326 SLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRD 3385
+ LED+LL +L+ + G+++D+ L+ L TK AAEV EKL +A T I ++
Sbjct: 3825 RKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQE 3884
Query: 3386 GYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDM 3445
+RP A RGSIL+F++++M+ VN MYQ SL+ +L +F S+ ++ + + KR+ NII+
Sbjct: 3885 EFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEY 3944
Query: 3446 LTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLE-KSARSSP 3504
LT V+ Y G++E HK LF M +K++ V + IKG +L+ K+ P
Sbjct: 3945 LTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKP 4004
Query: 3505 APWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLK 3564
W+ W ++++LS P FA + + I++ + W+ WFD D PE IP+ Y + L
Sbjct: 4005 YRWILDMTWLNLVELSK-LPQ-FAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLD 4062
Query: 3565 PFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPG 3624
L+L+R + DR YI ++ E+Y P +++L+ E++ TP++ LS G
Sbjct: 4063 TCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMG 4122
Query: 3625 SDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFL 3684
SDPT + LA + + + +S+GQGQE A L++ ++ G W++LQNCHL + F+
Sbjct: 4123 SDPTNQIDALAKKLKL---ECRTISMGQGQEVHARKLIQMSMQQGGWVLLQNCHLGLEFM 4179
Query: 3685 RELEKQLELMTKPHPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLNLRNTYFKMR 3741
EL + L +R+W+TT+P FPI +LQ SLK EPP G++ L+ T+ +
Sbjct: 4180 EELLETLITTEASDDSFRVWITTEPHDRFPITLLQTSLKFTNEPPQGVRAGLKRTFAGIN 4239
Query: 3742 ARALEECPHPQFKKLVYVLAFFHAVVQ 3768
L+ P +K ++Y +AF H+ VQ
Sbjct: 4240 QDLLDISNLPMWKPMLYTVAFLHSTVQ 4266
Score = 192 bits (469), Expect = 2e-47
Identities = 128/408 (31%), Positives = 201/408 (49%), Gaps = 17/408 (4%)
Query: 3745 LEECPHPQFKKLVYVLAFFHAVVQVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFH 3804
L+EC KK V + + +V YGG + + E +F+ F
Sbjct: 4298 LDEC---DIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMFEP--SFC 4352
Query: 3805 FYKDYAFDYVIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIE 3864
FY Y IP D+Y ++I +LP + PEVFGLHPNA+I Y S + +
Sbjct: 4353 FYTGYK----IPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQSNTASAVLETITN 4408
Query: 3865 LQPQTSEAGGAMSREDFIDNIAVDVLSKLPTLYEIWRVRKQ-FEM-NITPTLVVLLQELE 3922
+QP+ S G +RE + ++ D+LSKLP Y V+ + +M ++ + L QE++
Sbjct: 4409 IQPKESGGGVGETREAIVYRLSEDMLSKLPPDYIPHEVKSRLIKMGHLNSMNIFLRQEID 4468
Query: 3923 RFNRLISRMGSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGW 3982
R R+IS + S+LS L+ A+ G I M L + ++++ ++PQ+W+ ++ LG W
Sbjct: 4469 RMQRVISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQLWKRVS-WDSSTLGFW 4527
Query: 3983 MDHFIARTKQYTDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYT-WPLDRSTQFTKV 4041
+ R Q++ W P V W++G P+ +L A Q R + W LD T +V
Sbjct: 4528 FTELLERNAQFSTWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDTVTIHNEV 4587
Query: 4042 TSWVSADEIEERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHK 4101
+ +EI P G Y+ GLY++GA WD G L S PKVL T+LP+++I I
Sbjct: 4588 LR-QTKEEITSPPGEGVYIYGLYMDGAAWDRRNGKLMESTPKVLFTQLPVLHIFAINSTA 4646
Query: 4102 LKLQNTLRTPVYTTSQRRNAMGVGLVFESDLWTTEHCSHWILQGVCLI 4149
K P+Y +R + + +V+ L T HWIL+GV L+
Sbjct: 4647 PKDPKLYVCPIYKKPRRTDLTFITVVY---LRTVLSPDHWILRGVALL 4691
Score = 109 bits (262), Expect = 2e-22
Identities = 55/154 (35%), Positives = 85/154 (55%), Gaps = 2/154 (1%)
Query: 2515 RYYEDLLDYEAIYFLFQEILDEYNE--RNAKMSIVLFEDCLEHLTRTHRILRMDRGNAMX 2572
+ YE + ++ + Q ++NE R + +V F+D + HL + RI+R GNA+
Sbjct: 2964 KIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALL 3023
Query: 2573 XXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMYLQLGVDNKKTVFLFT 2632
+LA+F AG ++F+IT+TR+YN DD+K +Y G D K F+FT
Sbjct: 3024 VGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITFIFT 3083
Query: 2633 AAQILEEGFLEFINNILMIGMIPALFGDDEKDSI 2666
++I +E FLE++NN+L G I LF DE D I
Sbjct: 3084 DSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEI 3117
Score = 96.7 bits (230), Expect = 2e-18
Identities = 74/334 (22%), Positives = 156/334 (46%), Gaps = 22/334 (6%)
Query: 54 ERIFGLELKSIISDPT--QIDDVRKRVKNLVYPIRTVDFSVFVFDNKENWDVIMGDFWNE 111
E I ++ S +S+ T ID + + +N+ ++ + + + + +D DF +
Sbjct: 579 EMITVVQTYSTLSNSTIEGIDIMAIKFRNIYQGVKKKQYDI-LDPRRTEFDTDFLDFMTK 637
Query: 112 VRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEI 171
+ LE + + ++N SFG + SS++AL +L +F + + + +++ + +++ ++ E+
Sbjct: 638 INGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLNI-PCLGLEINHTIERILQYYVAEL 696
Query: 172 TAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMKQPIMKFQKVSELNECEQKKEAF 231
A + + + +PPL RN PP+AG I W R L+ ++ +PI F K S++ K
Sbjct: 697 DATKKLYHSQKDDPPLARNMPPIAGKILWVRQLYRRISEPINYFFKNSDILSSPDGKAVI 756
Query: 232 LQYKAFSKIIKEYEDTKYKEWVQDASLFCDNMMKKNILKVVFKKEDDP----VPQKARGM 287
QY S ++ E+E + W+++ S + + +F + + V + +
Sbjct: 757 RQYNKISYVLVEFEVVYHTAWIREIS-----QLHYALQATLFVRHPETGKLLVNFDPKIL 811
Query: 288 QLTAAGRAHVAKK-KASNTSLKPLDIVNKEIADKRRRDKAL-----MLMRIPGQHYENVR 341
++ + + K + + L + +K ADK L + +P + N+
Sbjct: 812 EVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPSV-FVNLM 870
Query: 342 SP--SSVSLLAKEGLTDVTWRDLTVHKLIQEYNL 373
+P V + ++GLT +TW LT+ QE L
Sbjct: 871 TPKMKKVESVLRQGLTVLTWSSLTLESFFQEVEL 904
Score = 42.7 bits (96), Expect = 0.027
Identities = 22/98 (22%), Positives = 48/98 (48%)
Query: 378 NFDKDLFLVIHEAELMEQLGFDVPSNVRDVAMQKSRLFYELEALSKIIAKYNKNASSLSP 437
NFD + V+ E + M ++ DVP + + +S+L + L ++ Y++ +
Sbjct: 805 NFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPS 864
Query: 438 SETYLMKRHLLDMERHILPGLTRITWTALGINDYIKDI 475
LM + +E + GLT +TW++L + + +++
Sbjct: 865 VFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQEV 902
>AL353700-2|CAI20293.1| 4176|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4176
Score = 849 bits (2100), Expect = 0.0
Identities = 540/1666 (32%), Positives = 877/1666 (52%), Gaps = 82/1666 (4%)
Query: 782 IKGLEDFKLVMATITQVQQMTITAEVKYRGMQEIFHMLKQHGINVTDEDLQFAKSLEASW 841
I+ L+D + M ++ ++ I ++ ++E + +L + + VT E+ + +L S+
Sbjct: 1318 IRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYSF 1377
Query: 842 GSLYQTSLFRGNTLEQTKEKFSKLNVVE-ISNFLKELDDFVEKFDNEGPATVEDDMDRGL 900
L ++ L Q + KF K N++E + F +++ +F E ++ EGP
Sbjct: 1378 NKLQSKAVSVQEDLVQVQPKF-KSNLLESVEVFREDVINFAEAYELEGPMVPNIPPQEAS 1436
Query: 901 LLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNFNRTKADYSAMDQIYKIYKAQKNA 960
++ + D+L + + EQLF P+ D+ ++T+ + + + ++Y +Y ++
Sbjct: 1437 NRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSS 1496
Query: 961 REVWAKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLMLDLKMKQFKGVVPLMVS 1020
+ + LW +++ + + + +F RKLPK ++ L L ++ F PL+
Sbjct: 1497 ISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEM 1556
Query: 1021 LKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMELHKYQDVAEEIVNHAIKELAIE 1080
+ N+AM++RHW + TG FD+ D F L N+ L K++D E+I AIKE IE
Sbjct: 1557 MTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIE 1616
Query: 1081 RGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVVKLDDDSMSLQSMAASQFIGPF 1140
+ V E W N + S + +GE +I+ ++D M L S+ ++++ PF
Sbjct: 1617 AKLTQVIENWTNQNLSFAAFKGKGELL-LKGTESGEIITLMEDSLMVLGSLLSNRYNAPF 1675
Query: 1141 LTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGGDIRTQLPEEAKKFDDIDRAFRK 1200
+Q W ++LS S+IIEEW+ Q W+YLE +FVGGDI QLP+EAK+F +ID+++ K
Sbjct: 1676 KKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIK 1735
Query: 1201 IMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASSDVTRKQINLSQAIAWADR 1260
IM + NV++CC +G + L Q +S + + +K++ + +D
Sbjct: 1736 IMQRAHENPNVINCC-VGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDP 1794
Query: 1261 ASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYVDHTNRPVAAKMISAEGEIMDF 1320
L ++ ++ Q S DNI + + +R +A +IS EGE +
Sbjct: 1795 VLLEILGQASDSHTIQPHLPAVS------DNINEVTFHAKDYDRIMA--VISREGEKIVL 1846
Query: 1321 RNVVYTEGRVEDWMNLVLVEMRHTNKFITKKAIFYYGKNWKVPRTDWILEYQGMVCLAAN 1380
N V +G VE W+ L L++M+ ++ ++ FY + ++ + V L
Sbjct: 1847 DNSVMAKGPVEIWL-LDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGLLGI 1905
Query: 1381 GVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQLDGLVVKVRQDLSSNDRLKFRTITTID 1440
+ WT ++EE LR K +++ M+ Q+ + L+ L+ + DLS DR+KF T+ TI
Sbjct: 1906 QMLWTHDSEEA-LRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIH 1964
Query: 1441 VHARDIIEGFVRDNITEAAEFEWESQLRFYWLKKDDNLWIRQCTGV-FEYGYEYMGLNGR 1499
VH RDI + V+ +I +FEW Q RFY+ K+D + + T V F Y E++G R
Sbjct: 1965 VHQRDIFDDLVKMHIKSPTDFEWLKQSRFYF-KEDLDQTVVSITDVDFIYQNEFLGCTDR 2023
Query: 1500 LVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDF 1559
LVITPLTDR Y+T+ QAL M + D+ + LG VV NC + MDF
Sbjct: 2024 LVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDF 2083
Query: 1560 RAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLKRFTVNTDVLKP 1619
R +G+I GL Q G+WGCFDEFNRI++ VLSV + Q+ + +A + K+F +
Sbjct: 2084 RGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD----- 2138
Query: 1620 SQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTELPESVKALFRPVVCILPDLEMI 1679
G + ++ + GIF+TMNPGYAGR ELPE++K FR V ++PD ++I
Sbjct: 2139 -------------GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQII 2185
Query: 1680 CQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTAVLRMAGKLRRDSPG 1739
++ L S GFL +LA+K VLYK+ EQL+KQ HYD+GLR + +VLR G +R P
Sbjct: 2186 MRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPE 2245
Query: 1740 LSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEKDG 1799
SE+ ++MR LRDMN K V ED PLFL LI DLFPGL+ Y E AV ++ +G
Sbjct: 2246 DSELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEG 2305
Query: 1800 YVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNLGLPTKLTVVNPK 1859
+ P K+VQLYET + RH M +GP+G GKT ++ L+KAQT G P + +NPK
Sbjct: 2306 LINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQTECGRPHREMRMNPK 2365
Query: 1860 ACSVIELYGILDPVTRDWTDGLYSKIFREMNRPAEKNERRYSLFDGDVDALWIENMNSVM 1919
A + +++G LD T DWTDG++S ++R+ + A+K E + + DG VDA+WIEN+NSV+
Sbjct: 2366 AITAPQMFGRLDTATNDWTDGIFSTLWRKTLK-AKKGENIFLILDGPVDAIWIENLNSVL 2424
Query: 1920 DDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGYEPYWERWL 1979
DDNK LTLANG+RI +AP C LLFEV ++ ASPATVSR GMV++ L + P + WL
Sbjct: 2425 DDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWL 2484
Query: 1980 STRSNEEEREQLSGLFEHYVPGAINYIVFGMFGLQQQTPLKTIVPQTPLNLVMQLCYMIS 2039
R+ +E L+ L+E Y+ + P ++ N ++Q ++
Sbjct: 2485 KKRTAQEAAVFLT-LYEKVFEDTYTYMKLNL------NPKMQLL---ECNYIVQSLNLLE 2534
Query: 2040 GLLPNNEDTNMEIDKTVVECVFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVEDNPE 2099
GL+P+ E+ + + + + +F+ + SLGA + R + ++++ E
Sbjct: 2535 GLIPSKEEGGVSCVEHLHK-LFVFGLMWSLGALLELESREKLEAFLRQ----------HE 2583
Query: 2100 KKATTKHFPMGF-PTLYDYCLELTTKLWEAWDWLVPEYEHDRDM--KFPAILVPTVDTLR 2156
K P G T+Y++ + WE W+ + Y + D ++ +ILVP VD +R
Sbjct: 2584 SKLDLPEIPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIR 2642
Query: 2157 LTWLIKIMESIIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMP 2216
+LI ++I +Q T Q ++V+ K + P V + P
Sbjct: 2643 TNFLI---DTIAKQHKAVLLTGE---QGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEP 2696
Query: 2217 ------IVSHNNQCVPSLCST---RVQTL----LSHPLVDTYGTQQPIALLKLLFERKGF 2263
I S+ ++ + S R T+ ++ P+++ +G Q +++ + E +G
Sbjct: 2697 MMFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGM 2756
Query: 2264 YDRGKDLNWKNLKDIGFLAAMGKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSIL 2323
Y K ++ + D+ +AAM GGGRND+ R F+V+N PS ++ I+ I
Sbjct: 2757 YSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIG 2816
Query: 2324 KGHFE---IFPEEIQGIVEKIVQMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMC 2380
G+F+ F +I ++ +V + L++ V++ PTP+KFHYIFNLRDLSRI GM
Sbjct: 2817 CGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGML 2876
Query: 2381 LTHANYFSEKRTVVRCWRNEFTRVICDRLINQQDNELMRGHIQEHV 2426
A + T++ +++E +RVI DR I +D + H+ V
Sbjct: 2877 TIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAV 2922
Score = 572 bits (1412), Expect = e-162
Identities = 326/999 (32%), Positives = 528/999 (52%), Gaps = 23/999 (2%)
Query: 2682 AKCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKI-PEEFRPIIVEHVVHVHMSV 2740
A+ FPGL++ T+DW WP++AL+AVA+ FL+D + E + +VE + H V
Sbjct: 3166 ARSLKFPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMV 3225
Query: 2741 ARYSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQ 2800
+ + R RR +VTPK Y+ F+ Y + EK FI Q ER+ GL K+ EA+
Sbjct: 3226 SESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASES 3285
Query: 2801 LEDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVE 2860
+ L+ LAV++ +A + + + +L E++ + + + + I E
Sbjct: 3286 VAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSE 3345
Query: 2861 KXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVII--RGIKD 2918
K NDI +R A PP + + +CV+++ + I
Sbjct: 3346 KVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDP 3405
Query: 2919 V-----------SWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLDTM 2966
V SW + +M+ FL +LQ+ D I + V+ ++ + ++
Sbjct: 3406 VTMDPEKSCCKPSWGESLKLMSATGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESA 3465
Query: 2967 QQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQK 3026
+++ GLL + A+ + + A L +D Q
Sbjct: 3466 KKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQA 3525
Query: 3027 TLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSR 3086
LD + +++ AM + +L + D +++ AA L+ GLS E+ RWT+ + +R
Sbjct: 3526 ELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINR 3585
Query: 3087 LIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSG 3146
L+G+ LL T FLSY GPF+ FR ++ + W ++ R IP T + L + +
Sbjct: 3586 LVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARKIPFTENLNLISMLVDPPTIGE 3645
Query: 3147 WNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLR 3206
W +GLP D+LS+QNGI+ T+A+R+PL IDPQTQ TWIK KE +N+L+V S N F
Sbjct: 3646 WGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRT 3705
Query: 3207 QLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTF-VMLGSTEVDYDPNFRMYL 3265
LE ++ G P+L +D++E +DP +DNVLEKN ++SG TF V +G E D F++Y+
Sbjct: 3706 HLEDSLSLGRPLLIEDIHEELDPALDNVLEKNF-IKSGTTFKVKVGDKECDIMDTFKLYI 3764
Query: 3266 TTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANK 3325
TTKL NP F P AK VI++TVT++GLE+QLL V+ E+ +LE +R L+ + + NK
Sbjct: 3765 TTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNK 3824
Query: 3326 SLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRD 3385
+ LED+LL +L+ + G+++D+ L+ L TK AAEV EKL +A T I ++
Sbjct: 3825 RKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQE 3884
Query: 3386 GYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDM 3445
+RP A RGSIL+F++++M+ VN MYQ SL+ +L +F S+ ++ + + KR+ NII+
Sbjct: 3885 EFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEY 3944
Query: 3446 LTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLE-KSARSSP 3504
LT V+ Y G++E HK LF M +K++ V + IKG +L+ K+ P
Sbjct: 3945 LTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKP 4004
Query: 3505 APWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLK 3564
W+ W ++++LS P FA + + I++ + W+ WFD D PE IP+ Y + L
Sbjct: 4005 YRWILDMTWLNLVELSK-LPQ-FAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLD 4062
Query: 3565 PFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPG 3624
L+L+R + DR YI ++ E+Y P +++L+ E++ TP++ LS G
Sbjct: 4063 TCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMG 4122
Query: 3625 SDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLE 3663
SDPT + LA + + + +S+GQGQE A L++
Sbjct: 4123 SDPTNQIDALAKKLKL---ECRTISMGQGQEVHARKLIQ 4158
Score = 109 bits (262), Expect = 2e-22
Identities = 55/154 (35%), Positives = 85/154 (55%), Gaps = 2/154 (1%)
Query: 2515 RYYEDLLDYEAIYFLFQEILDEYNE--RNAKMSIVLFEDCLEHLTRTHRILRMDRGNAMX 2572
+ YE + ++ + Q ++NE R + +V F+D + HL + RI+R GNA+
Sbjct: 2964 KIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALL 3023
Query: 2573 XXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMYLQLGVDNKKTVFLFT 2632
+LA+F AG ++F+IT+TR+YN DD+K +Y G D K F+FT
Sbjct: 3024 VGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITFIFT 3083
Query: 2633 AAQILEEGFLEFINNILMIGMIPALFGDDEKDSI 2666
++I +E FLE++NN+L G I LF DE D I
Sbjct: 3084 DSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEI 3117
Score = 96.7 bits (230), Expect = 2e-18
Identities = 74/334 (22%), Positives = 156/334 (46%), Gaps = 22/334 (6%)
Query: 54 ERIFGLELKSIISDPT--QIDDVRKRVKNLVYPIRTVDFSVFVFDNKENWDVIMGDFWNE 111
E I ++ S +S+ T ID + + +N+ ++ + + + + +D DF +
Sbjct: 579 EMITVVQTYSTLSNSTIEGIDIMAIKFRNIYQGVKKKQYDI-LDPRRTEFDTDFLDFMTK 637
Query: 112 VRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEI 171
+ LE + + ++N SFG + SS++AL +L +F + + + +++ + +++ ++ E+
Sbjct: 638 INGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLNI-PCLGLEINHTIERILQYYVAEL 696
Query: 172 TAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMKQPIMKFQKVSELNECEQKKEAF 231
A + + + +PPL RN PP+AG I W R L+ ++ +PI F K S++ K
Sbjct: 697 DATKKLYHSQKDDPPLARNMPPIAGKILWVRQLYRRISEPINYFFKNSDILSSPDGKAVI 756
Query: 232 LQYKAFSKIIKEYEDTKYKEWVQDASLFCDNMMKKNILKVVFKKEDDP----VPQKARGM 287
QY S ++ E+E + W+++ S + + +F + + V + +
Sbjct: 757 RQYNKISYVLVEFEVVYHTAWIREIS-----QLHYALQATLFVRHPETGKLLVNFDPKIL 811
Query: 288 QLTAAGRAHVAKK-KASNTSLKPLDIVNKEIADKRRRDKAL-----MLMRIPGQHYENVR 341
++ + + K + + L + +K ADK L + +P + N+
Sbjct: 812 EVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPSV-FVNLM 870
Query: 342 SP--SSVSLLAKEGLTDVTWRDLTVHKLIQEYNL 373
+P V + ++GLT +TW LT+ QE L
Sbjct: 871 TPKMKKVESVLRQGLTVLTWSSLTLESFFQEVEL 904
Score = 42.7 bits (96), Expect = 0.027
Identities = 22/98 (22%), Positives = 48/98 (48%)
Query: 378 NFDKDLFLVIHEAELMEQLGFDVPSNVRDVAMQKSRLFYELEALSKIIAKYNKNASSLSP 437
NFD + V+ E + M ++ DVP + + +S+L + L ++ Y++ +
Sbjct: 805 NFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPS 864
Query: 438 SETYLMKRHLLDMERHILPGLTRITWTALGINDYIKDI 475
LM + +E + GLT +TW++L + + +++
Sbjct: 865 VFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQEV 902
>AL353700-1|CAI20292.1| 4490|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4490
Score = 849 bits (2100), Expect = 0.0
Identities = 540/1666 (32%), Positives = 877/1666 (52%), Gaps = 82/1666 (4%)
Query: 782 IKGLEDFKLVMATITQVQQMTITAEVKYRGMQEIFHMLKQHGINVTDEDLQFAKSLEASW 841
I+ L+D + M ++ ++ I ++ ++E + +L + + VT E+ + +L S+
Sbjct: 1113 IRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYSF 1172
Query: 842 GSLYQTSLFRGNTLEQTKEKFSKLNVVE-ISNFLKELDDFVEKFDNEGPATVEDDMDRGL 900
L ++ L Q + KF K N++E + F +++ +F E ++ EGP
Sbjct: 1173 NKLQSKAVSVQEDLVQVQPKF-KSNLLESVEVFREDVINFAEAYELEGPMVPNIPPQEAS 1231
Query: 901 LLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNFNRTKADYSAMDQIYKIYKAQKNA 960
++ + D+L + + EQLF P+ D+ ++T+ + + + ++Y +Y ++
Sbjct: 1232 NRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSS 1291
Query: 961 REVWAKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLMLDLKMKQFKGVVPLMVS 1020
+ + LW +++ + + + +F RKLPK ++ L L ++ F PL+
Sbjct: 1292 ISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEM 1351
Query: 1021 LKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMELHKYQDVAEEIVNHAIKELAIE 1080
+ N+AM++RHW + TG FD+ D F L N+ L K++D E+I AIKE IE
Sbjct: 1352 MTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIE 1411
Query: 1081 RGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVVKLDDDSMSLQSMAASQFIGPF 1140
+ V E W N + S + +GE +I+ ++D M L S+ ++++ PF
Sbjct: 1412 AKLTQVIENWTNQNLSFAAFKGKGELL-LKGTESGEIITLMEDSLMVLGSLLSNRYNAPF 1470
Query: 1141 LTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGGDIRTQLPEEAKKFDDIDRAFRK 1200
+Q W ++LS S+IIEEW+ Q W+YLE +FVGGDI QLP+EAK+F +ID+++ K
Sbjct: 1471 KKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIK 1530
Query: 1201 IMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASSDVTRKQINLSQAIAWADR 1260
IM + NV++CC +G + L Q +S + + +K++ + +D
Sbjct: 1531 IMQRAHENPNVINCC-VGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDP 1589
Query: 1261 ASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYVDHTNRPVAAKMISAEGEIMDF 1320
L ++ ++ Q S DNI + + +R +A +IS EGE +
Sbjct: 1590 VLLEILGQASDSHTIQPHLPAVS------DNINEVTFHAKDYDRIMA--VISREGEKIVL 1641
Query: 1321 RNVVYTEGRVEDWMNLVLVEMRHTNKFITKKAIFYYGKNWKVPRTDWILEYQGMVCLAAN 1380
N V +G VE W+ L L++M+ ++ ++ FY + ++ + V L
Sbjct: 1642 DNSVMAKGPVEIWL-LDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGLLGI 1700
Query: 1381 GVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQLDGLVVKVRQDLSSNDRLKFRTITTID 1440
+ WT ++EE LR K +++ M+ Q+ + L+ L+ + DLS DR+KF T+ TI
Sbjct: 1701 QMLWTHDSEEA-LRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIH 1759
Query: 1441 VHARDIIEGFVRDNITEAAEFEWESQLRFYWLKKDDNLWIRQCTGV-FEYGYEYMGLNGR 1499
VH RDI + V+ +I +FEW Q RFY+ K+D + + T V F Y E++G R
Sbjct: 1760 VHQRDIFDDLVKMHIKSPTDFEWLKQSRFYF-KEDLDQTVVSITDVDFIYQNEFLGCTDR 1818
Query: 1500 LVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDF 1559
LVITPLTDR Y+T+ QAL M + D+ + LG VV NC + MDF
Sbjct: 1819 LVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDF 1878
Query: 1560 RAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLKRFTVNTDVLKP 1619
R +G+I GL Q G+WGCFDEFNRI++ VLSV + Q+ + +A + K+F +
Sbjct: 1879 RGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD----- 1933
Query: 1620 SQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTELPESVKALFRPVVCILPDLEMI 1679
G + ++ + GIF+TMNPGYAGR ELPE++K FR V ++PD ++I
Sbjct: 1934 -------------GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQII 1980
Query: 1680 CQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTAVLRMAGKLRRDSPG 1739
++ L S GFL +LA+K VLYK+ EQL+KQ HYD+GLR + +VLR G +R P
Sbjct: 1981 MRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPE 2040
Query: 1740 LSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEKDG 1799
SE+ ++MR LRDMN K V ED PLFL LI DLFPGL+ Y E AV ++ +G
Sbjct: 2041 DSELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEG 2100
Query: 1800 YVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNLGLPTKLTVVNPK 1859
+ P K+VQLYET + RH M +GP+G GKT ++ L+KAQT G P + +NPK
Sbjct: 2101 LINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQTECGRPHREMRMNPK 2160
Query: 1860 ACSVIELYGILDPVTRDWTDGLYSKIFREMNRPAEKNERRYSLFDGDVDALWIENMNSVM 1919
A + +++G LD T DWTDG++S ++R+ + A+K E + + DG VDA+WIEN+NSV+
Sbjct: 2161 AITAPQMFGRLDTATNDWTDGIFSTLWRKTLK-AKKGENIFLILDGPVDAIWIENLNSVL 2219
Query: 1920 DDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGYEPYWERWL 1979
DDNK LTLANG+RI +AP C LLFEV ++ ASPATVSR GMV++ L + P + WL
Sbjct: 2220 DDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWL 2279
Query: 1980 STRSNEEEREQLSGLFEHYVPGAINYIVFGMFGLQQQTPLKTIVPQTPLNLVMQLCYMIS 2039
R+ +E L+ L+E Y+ + P ++ N ++Q ++
Sbjct: 2280 KKRTAQEAAVFLT-LYEKVFEDTYTYMKLNL------NPKMQLL---ECNYIVQSLNLLE 2329
Query: 2040 GLLPNNEDTNMEIDKTVVECVFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVEDNPE 2099
GL+P+ E+ + + + + +F+ + SLGA + R + ++++ E
Sbjct: 2330 GLIPSKEEGGVSCVEHLHK-LFVFGLMWSLGALLELESREKLEAFLRQ----------HE 2378
Query: 2100 KKATTKHFPMGF-PTLYDYCLELTTKLWEAWDWLVPEYEHDRDM--KFPAILVPTVDTLR 2156
K P G T+Y++ + WE W+ + Y + D ++ +ILVP VD +R
Sbjct: 2379 SKLDLPEIPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIR 2437
Query: 2157 LTWLIKIMESIIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMP 2216
+LI ++I +Q T Q ++V+ K + P V + P
Sbjct: 2438 TNFLI---DTIAKQHKAVLLTGE---QGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEP 2491
Query: 2217 ------IVSHNNQCVPSLCST---RVQTL----LSHPLVDTYGTQQPIALLKLLFERKGF 2263
I S+ ++ + S R T+ ++ P+++ +G Q +++ + E +G
Sbjct: 2492 MMFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGM 2551
Query: 2264 YDRGKDLNWKNLKDIGFLAAMGKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSIL 2323
Y K ++ + D+ +AAM GGGRND+ R F+V+N PS ++ I+ I
Sbjct: 2552 YSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIG 2611
Query: 2324 KGHFE---IFPEEIQGIVEKIVQMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMC 2380
G+F+ F +I ++ +V + L++ V++ PTP+KFHYIFNLRDLSRI GM
Sbjct: 2612 CGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGML 2671
Query: 2381 LTHANYFSEKRTVVRCWRNEFTRVICDRLINQQDNELMRGHIQEHV 2426
A + T++ +++E +RVI DR I +D + H+ V
Sbjct: 2672 TIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAV 2717
Score = 652 bits (1612), Expect = 0.0
Identities = 366/1107 (33%), Positives = 591/1107 (53%), Gaps = 26/1107 (2%)
Query: 2682 AKCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKI-PEEFRPIIVEHVVHVHMSV 2740
A+ FPGL++ T+DW WP++AL+AVA+ FL+D + E + +VE + H V
Sbjct: 2961 ARSLKFPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMV 3020
Query: 2741 ARYSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQ 2800
+ + R RR +VTPK Y+ F+ Y + EK FI Q ER+ GL K+ EA+
Sbjct: 3021 SESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASES 3080
Query: 2801 LEDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVE 2860
+ L+ LAV++ +A + + + +L E++ + + + + I E
Sbjct: 3081 VAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSE 3140
Query: 2861 KXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVII--RGIKD 2918
K NDI +R A PP + + +CV+++ + I
Sbjct: 3141 KVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDP 3200
Query: 2919 V-----------SWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLDTM 2966
V SW + +M+ FL +LQ+ D I + V+ ++ + ++
Sbjct: 3201 VTMDPEKSCCKPSWGESLKLMSATGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESA 3260
Query: 2967 QQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQK 3026
+++ GLL + A+ + + A L +D Q
Sbjct: 3261 KKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQA 3320
Query: 3027 TLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSR 3086
LD + +++ AM + +L + D +++ AA L+ GLS E+ RWT+ + +R
Sbjct: 3321 ELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINR 3380
Query: 3087 LIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSG 3146
L+G+ LL T FLSY GPF+ FR ++ + W ++ R IP T + L + +
Sbjct: 3381 LVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARKIPFTENLNLISMLVDPPTIGE 3440
Query: 3147 WNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLR 3206
W +GLP D+LS+QNGI+ T+A+R+PL IDPQTQ TWIK KE +N+L+V S N F
Sbjct: 3441 WGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRT 3500
Query: 3207 QLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTF-VMLGSTEVDYDPNFRMYL 3265
LE ++ G P+L +D++E +DP +DNVLEKN ++SG TF V +G E D F++Y+
Sbjct: 3501 HLEDSLSLGRPLLIEDIHEELDPALDNVLEKNF-IKSGTTFKVKVGDKECDIMDTFKLYI 3559
Query: 3266 TTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANK 3325
TTKL NP F P AK VI++TVT++GLE+QLL V+ E+ +LE +R L+ + + NK
Sbjct: 3560 TTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNK 3619
Query: 3326 SLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRD 3385
+ LED+LL +L+ + G+++D+ L+ L TK AAEV EKL +A T I ++
Sbjct: 3620 RKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQE 3679
Query: 3386 GYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDM 3445
+RP A RGSIL+F++++M+ VN MYQ SL+ +L +F S+ ++ + + KR+ NII+
Sbjct: 3680 EFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEY 3739
Query: 3446 LTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLE-KSARSSP 3504
LT V+ Y G++E HK LF M +K++ V + IKG +L+ K+ P
Sbjct: 3740 LTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKP 3799
Query: 3505 APWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLK 3564
W+ W ++++LS P FA + + I++ + W+ WFD D PE IP+ Y + L
Sbjct: 3800 YRWILDMTWLNLVELSK-LPQ-FAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLD 3857
Query: 3565 PFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPG 3624
L+L+R + DR YI ++ E+Y P +++L+ E++ TP++ LS G
Sbjct: 3858 TCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMG 3917
Query: 3625 SDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFL 3684
SDPT + LA + + + +S+GQGQE A L++ ++ G W++LQNCHL + F+
Sbjct: 3918 SDPTNQIDALAKKLKL---ECRTISMGQGQEVHARKLIQMSMQQGGWVLLQNCHLGLEFM 3974
Query: 3685 RELEKQLELMTKPHPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLNLRNTYFKMR 3741
EL + L +R+W+TT+P FPI +LQ SLK EPP G++ L+ T+ +
Sbjct: 3975 EELLETLITTEASDDSFRVWITTEPHDRFPITLLQTSLKFTNEPPQGVRAGLKRTFAGIN 4034
Query: 3742 ARALEECPHPQFKKLVYVLAFFHAVVQ 3768
L+ P +K ++Y +AF H+ VQ
Sbjct: 4035 QDLLDISNLPMWKPMLYTVAFLHSTVQ 4061
Score = 192 bits (469), Expect = 2e-47
Identities = 128/408 (31%), Positives = 201/408 (49%), Gaps = 17/408 (4%)
Query: 3745 LEECPHPQFKKLVYVLAFFHAVVQVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFH 3804
L+EC KK V + + +V YGG + + E +F+ F
Sbjct: 4093 LDEC---DIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMFEP--SFC 4147
Query: 3805 FYKDYAFDYVIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIE 3864
FY Y IP D+Y ++I +LP + PEVFGLHPNA+I Y S + +
Sbjct: 4148 FYTGYK----IPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQSNTASAVLETITN 4203
Query: 3865 LQPQTSEAGGAMSREDFIDNIAVDVLSKLPTLYEIWRVRKQ-FEM-NITPTLVVLLQELE 3922
+QP+ S G +RE + ++ D+LSKLP Y V+ + +M ++ + L QE++
Sbjct: 4204 IQPKESGGGVGETREAIVYRLSEDMLSKLPPDYIPHEVKSRLIKMGHLNSMNIFLRQEID 4263
Query: 3923 RFNRLISRMGSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGW 3982
R R+IS + S+LS L+ A+ G I M L + ++++ ++PQ+W+ ++ LG W
Sbjct: 4264 RMQRVISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQLWKRVS-WDSSTLGFW 4322
Query: 3983 MDHFIARTKQYTDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYT-WPLDRSTQFTKV 4041
+ R Q++ W P V W++G P+ +L A Q R + W LD T +V
Sbjct: 4323 FTELLERNAQFSTWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDTVTIHNEV 4382
Query: 4042 TSWVSADEIEERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHK 4101
+ +EI P G Y+ GLY++GA WD G L S PKVL T+LP+++I I
Sbjct: 4383 LR-QTKEEITSPPGEGVYIYGLYMDGAAWDRRNGKLMESTPKVLFTQLPVLHIFAINSTA 4441
Query: 4102 LKLQNTLRTPVYTTSQRRNAMGVGLVFESDLWTTEHCSHWILQGVCLI 4149
K P+Y +R + + +V+ L T HWIL+GV L+
Sbjct: 4442 PKDPKLYVCPIYKKPRRTDLTFITVVY---LRTVLSPDHWILRGVALL 4486
Score = 109 bits (262), Expect = 2e-22
Identities = 55/154 (35%), Positives = 85/154 (55%), Gaps = 2/154 (1%)
Query: 2515 RYYEDLLDYEAIYFLFQEILDEYNE--RNAKMSIVLFEDCLEHLTRTHRILRMDRGNAMX 2572
+ YE + ++ + Q ++NE R + +V F+D + HL + RI+R GNA+
Sbjct: 2759 KIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALL 2818
Query: 2573 XXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMYLQLGVDNKKTVFLFT 2632
+LA+F AG ++F+IT+TR+YN DD+K +Y G D K F+FT
Sbjct: 2819 VGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITFIFT 2878
Query: 2633 AAQILEEGFLEFINNILMIGMIPALFGDDEKDSI 2666
++I +E FLE++NN+L G I LF DE D I
Sbjct: 2879 DSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEI 2912
Score = 96.7 bits (230), Expect = 2e-18
Identities = 74/334 (22%), Positives = 156/334 (46%), Gaps = 22/334 (6%)
Query: 54 ERIFGLELKSIISDPT--QIDDVRKRVKNLVYPIRTVDFSVFVFDNKENWDVIMGDFWNE 111
E I ++ S +S+ T ID + + +N+ ++ + + + + +D DF +
Sbjct: 374 EMITVVQTYSTLSNSTIEGIDIMAIKFRNIYQGVKKKQYDI-LDPRRTEFDTDFLDFMTK 432
Query: 112 VRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEI 171
+ LE + + ++N SFG + SS++AL +L +F + + + +++ + +++ ++ E+
Sbjct: 433 INGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLNI-PCLGLEINHTIERILQYYVAEL 491
Query: 172 TAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMKQPIMKFQKVSELNECEQKKEAF 231
A + + + +PPL RN PP+AG I W R L+ ++ +PI F K S++ K
Sbjct: 492 DATKKLYHSQKDDPPLARNMPPIAGKILWVRQLYRRISEPINYFFKNSDILSSPDGKAVI 551
Query: 232 LQYKAFSKIIKEYEDTKYKEWVQDASLFCDNMMKKNILKVVFKKEDDP----VPQKARGM 287
QY S ++ E+E + W+++ S + + +F + + V + +
Sbjct: 552 RQYNKISYVLVEFEVVYHTAWIREIS-----QLHYALQATLFVRHPETGKLLVNFDPKIL 606
Query: 288 QLTAAGRAHVAKK-KASNTSLKPLDIVNKEIADKRRRDKAL-----MLMRIPGQHYENVR 341
++ + + K + + L + +K ADK L + +P + N+
Sbjct: 607 EVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPSV-FVNLM 665
Query: 342 SP--SSVSLLAKEGLTDVTWRDLTVHKLIQEYNL 373
+P V + ++GLT +TW LT+ QE L
Sbjct: 666 TPKMKKVESVLRQGLTVLTWSSLTLESFFQEVEL 699
Score = 42.7 bits (96), Expect = 0.027
Identities = 22/98 (22%), Positives = 48/98 (48%)
Query: 378 NFDKDLFLVIHEAELMEQLGFDVPSNVRDVAMQKSRLFYELEALSKIIAKYNKNASSLSP 437
NFD + V+ E + M ++ DVP + + +S+L + L ++ Y++ +
Sbjct: 600 NFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPS 659
Query: 438 SETYLMKRHLLDMERHILPGLTRITWTALGINDYIKDI 475
LM + +E + GLT +TW++L + + +++
Sbjct: 660 VFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQEV 697
>AL035690-5|CAI19770.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 849 bits (2100), Expect = 0.0
Identities = 540/1666 (32%), Positives = 877/1666 (52%), Gaps = 82/1666 (4%)
Query: 782 IKGLEDFKLVMATITQVQQMTITAEVKYRGMQEIFHMLKQHGINVTDEDLQFAKSLEASW 841
I+ L+D + M ++ ++ I ++ ++E + +L + + VT E+ + +L S+
Sbjct: 1318 IRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYSF 1377
Query: 842 GSLYQTSLFRGNTLEQTKEKFSKLNVVE-ISNFLKELDDFVEKFDNEGPATVEDDMDRGL 900
L ++ L Q + KF K N++E + F +++ +F E ++ EGP
Sbjct: 1378 NKLQSKAVSVQEDLVQVQPKF-KSNLLESVEVFREDVINFAEAYELEGPMVPNIPPQEAS 1436
Query: 901 LLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNFNRTKADYSAMDQIYKIYKAQKNA 960
++ + D+L + + EQLF P+ D+ ++T+ + + + ++Y +Y ++
Sbjct: 1437 NRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSS 1496
Query: 961 REVWAKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLMLDLKMKQFKGVVPLMVS 1020
+ + LW +++ + + + +F RKLPK ++ L L ++ F PL+
Sbjct: 1497 ISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEM 1556
Query: 1021 LKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMELHKYQDVAEEIVNHAIKELAIE 1080
+ N+AM++RHW + TG FD+ D F L N+ L K++D E+I AIKE IE
Sbjct: 1557 MTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIE 1616
Query: 1081 RGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVVKLDDDSMSLQSMAASQFIGPF 1140
+ V E W N + S + +GE +I+ ++D M L S+ ++++ PF
Sbjct: 1617 AKLTQVIENWTNQNLSFAAFKGKGELL-LKGTESGEIITLMEDSLMVLGSLLSNRYNAPF 1675
Query: 1141 LTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGGDIRTQLPEEAKKFDDIDRAFRK 1200
+Q W ++LS S+IIEEW+ Q W+YLE +FVGGDI QLP+EAK+F +ID+++ K
Sbjct: 1676 KKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIK 1735
Query: 1201 IMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASSDVTRKQINLSQAIAWADR 1260
IM + NV++CC +G + L Q +S + + +K++ + +D
Sbjct: 1736 IMQRAHENPNVINCC-VGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDP 1794
Query: 1261 ASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYVDHTNRPVAAKMISAEGEIMDF 1320
L ++ ++ Q S DNI + + +R +A +IS EGE +
Sbjct: 1795 VLLEILGQASDSHTIQPHLPAVS------DNINEVTFHAKDYDRIMA--VISREGEKIVL 1846
Query: 1321 RNVVYTEGRVEDWMNLVLVEMRHTNKFITKKAIFYYGKNWKVPRTDWILEYQGMVCLAAN 1380
N V +G VE W+ L L++M+ ++ ++ FY + ++ + V L
Sbjct: 1847 DNSVMAKGPVEIWL-LDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGLLGI 1905
Query: 1381 GVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQLDGLVVKVRQDLSSNDRLKFRTITTID 1440
+ WT ++EE LR K +++ M+ Q+ + L+ L+ + DLS DR+KF T+ TI
Sbjct: 1906 QMLWTHDSEEA-LRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIH 1964
Query: 1441 VHARDIIEGFVRDNITEAAEFEWESQLRFYWLKKDDNLWIRQCTGV-FEYGYEYMGLNGR 1499
VH RDI + V+ +I +FEW Q RFY+ K+D + + T V F Y E++G R
Sbjct: 1965 VHQRDIFDDLVKMHIKSPTDFEWLKQSRFYF-KEDLDQTVVSITDVDFIYQNEFLGCTDR 2023
Query: 1500 LVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDF 1559
LVITPLTDR Y+T+ QAL M + D+ + LG VV NC + MDF
Sbjct: 2024 LVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDF 2083
Query: 1560 RAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLKRFTVNTDVLKP 1619
R +G+I GL Q G+WGCFDEFNRI++ VLSV + Q+ + +A + K+F +
Sbjct: 2084 RGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD----- 2138
Query: 1620 SQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTELPESVKALFRPVVCILPDLEMI 1679
G + ++ + GIF+TMNPGYAGR ELPE++K FR V ++PD ++I
Sbjct: 2139 -------------GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQII 2185
Query: 1680 CQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTAVLRMAGKLRRDSPG 1739
++ L S GFL +LA+K VLYK+ EQL+KQ HYD+GLR + +VLR G +R P
Sbjct: 2186 MRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPE 2245
Query: 1740 LSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEKDG 1799
SE+ ++MR LRDMN K V ED PLFL LI DLFPGL+ Y E AV ++ +G
Sbjct: 2246 DSELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEG 2305
Query: 1800 YVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNLGLPTKLTVVNPK 1859
+ P K+VQLYET + RH M +GP+G GKT ++ L+KAQT G P + +NPK
Sbjct: 2306 LINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQTECGRPHREMRMNPK 2365
Query: 1860 ACSVIELYGILDPVTRDWTDGLYSKIFREMNRPAEKNERRYSLFDGDVDALWIENMNSVM 1919
A + +++G LD T DWTDG++S ++R+ + A+K E + + DG VDA+WIEN+NSV+
Sbjct: 2366 AITAPQMFGRLDTATNDWTDGIFSTLWRKTLK-AKKGENIFLILDGPVDAIWIENLNSVL 2424
Query: 1920 DDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGYEPYWERWL 1979
DDNK LTLANG+RI +AP C LLFEV ++ ASPATVSR GMV++ L + P + WL
Sbjct: 2425 DDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWL 2484
Query: 1980 STRSNEEEREQLSGLFEHYVPGAINYIVFGMFGLQQQTPLKTIVPQTPLNLVMQLCYMIS 2039
R+ +E L+ L+E Y+ + P ++ N ++Q ++
Sbjct: 2485 KKRTAQEAAVFLT-LYEKVFEDTYTYMKLNL------NPKMQLL---ECNYIVQSLNLLE 2534
Query: 2040 GLLPNNEDTNMEIDKTVVECVFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVEDNPE 2099
GL+P+ E+ + + + + +F+ + SLGA + R + ++++ E
Sbjct: 2535 GLIPSKEEGGVSCVEHLHK-LFVFGLMWSLGALLELESREKLEAFLRQ----------HE 2583
Query: 2100 KKATTKHFPMGF-PTLYDYCLELTTKLWEAWDWLVPEYEHDRDM--KFPAILVPTVDTLR 2156
K P G T+Y++ + WE W+ + Y + D ++ +ILVP VD +R
Sbjct: 2584 SKLDLPEIPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIR 2642
Query: 2157 LTWLIKIMESIIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMP 2216
+LI ++I +Q T Q ++V+ K + P V + P
Sbjct: 2643 TNFLI---DTIAKQHKAVLLTGE---QGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEP 2696
Query: 2217 ------IVSHNNQCVPSLCST---RVQTL----LSHPLVDTYGTQQPIALLKLLFERKGF 2263
I S+ ++ + S R T+ ++ P+++ +G Q +++ + E +G
Sbjct: 2697 MMFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGM 2756
Query: 2264 YDRGKDLNWKNLKDIGFLAAMGKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSIL 2323
Y K ++ + D+ +AAM GGGRND+ R F+V+N PS ++ I+ I
Sbjct: 2757 YSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIG 2816
Query: 2324 KGHFE---IFPEEIQGIVEKIVQMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMC 2380
G+F+ F +I ++ +V + L++ V++ PTP+KFHYIFNLRDLSRI GM
Sbjct: 2817 CGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGML 2876
Query: 2381 LTHANYFSEKRTVVRCWRNEFTRVICDRLINQQDNELMRGHIQEHV 2426
A + T++ +++E +RVI DR I +D + H+ V
Sbjct: 2877 TIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAV 2922
Score = 652 bits (1612), Expect = 0.0
Identities = 366/1107 (33%), Positives = 591/1107 (53%), Gaps = 26/1107 (2%)
Query: 2682 AKCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKI-PEEFRPIIVEHVVHVHMSV 2740
A+ FPGL++ T+DW WP++AL+AVA+ FL+D + E + +VE + H V
Sbjct: 3166 ARSLKFPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMV 3225
Query: 2741 ARYSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQ 2800
+ + R RR +VTPK Y+ F+ Y + EK FI Q ER+ GL K+ EA+
Sbjct: 3226 SESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASES 3285
Query: 2801 LEDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVE 2860
+ L+ LAV++ +A + + + +L E++ + + + + I E
Sbjct: 3286 VAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSE 3345
Query: 2861 KXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVII--RGIKD 2918
K NDI +R A PP + + +CV+++ + I
Sbjct: 3346 KVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDP 3405
Query: 2919 V-----------SWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLDTM 2966
V SW + +M+ FL +LQ+ D I + V+ ++ + ++
Sbjct: 3406 VTMDPEKSCCKPSWGESLKLMSATGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESA 3465
Query: 2967 QQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQK 3026
+++ GLL + A+ + + A L +D Q
Sbjct: 3466 KKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQA 3525
Query: 3027 TLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSR 3086
LD + +++ AM + +L + D +++ AA L+ GLS E+ RWT+ + +R
Sbjct: 3526 ELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINR 3585
Query: 3087 LIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSG 3146
L+G+ LL T FLSY GPF+ FR ++ + W ++ R IP T + L + +
Sbjct: 3586 LVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARKIPFTENLNLISMLVDPPTIGE 3645
Query: 3147 WNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLR 3206
W +GLP D+LS+QNGI+ T+A+R+PL IDPQTQ TWIK KE +N+L+V S N F
Sbjct: 3646 WGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRT 3705
Query: 3207 QLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTF-VMLGSTEVDYDPNFRMYL 3265
LE ++ G P+L +D++E +DP +DNVLEKN ++SG TF V +G E D F++Y+
Sbjct: 3706 HLEDSLSLGRPLLIEDIHEELDPALDNVLEKNF-IKSGTTFKVKVGDKECDIMDTFKLYI 3764
Query: 3266 TTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANK 3325
TTKL NP F P AK VI++TVT++GLE+QLL V+ E+ +LE +R L+ + + NK
Sbjct: 3765 TTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNK 3824
Query: 3326 SLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRD 3385
+ LED+LL +L+ + G+++D+ L+ L TK AAEV EKL +A T I ++
Sbjct: 3825 RKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQE 3884
Query: 3386 GYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDM 3445
+RP A RGSIL+F++++M+ VN MYQ SL+ +L +F S+ ++ + + KR+ NII+
Sbjct: 3885 EFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEY 3944
Query: 3446 LTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLE-KSARSSP 3504
LT V+ Y G++E HK LF M +K++ V + IKG +L+ K+ P
Sbjct: 3945 LTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKP 4004
Query: 3505 APWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLK 3564
W+ W ++++LS P FA + + I++ + W+ WFD D PE IP+ Y + L
Sbjct: 4005 YRWILDMTWLNLVELSK-LPQ-FAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLD 4062
Query: 3565 PFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPG 3624
L+L+R + DR YI ++ E+Y P +++L+ E++ TP++ LS G
Sbjct: 4063 TCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMG 4122
Query: 3625 SDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFL 3684
SDPT + LA + + + +S+GQGQE A L++ ++ G W++LQNCHL + F+
Sbjct: 4123 SDPTNQIDALAKKLKL---ECRTISMGQGQEVHARKLIQMSMQQGGWVLLQNCHLGLEFM 4179
Query: 3685 RELEKQLELMTKPHPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLNLRNTYFKMR 3741
EL + L +R+W+TT+P FPI +LQ SLK EPP G++ L+ T+ +
Sbjct: 4180 EELLETLITTEASDDSFRVWITTEPHDRFPITLLQTSLKFTNEPPQGVRAGLKRTFAGIN 4239
Query: 3742 ARALEECPHPQFKKLVYVLAFFHAVVQ 3768
L+ P +K ++Y +AF H+ VQ
Sbjct: 4240 QDLLDISNLPMWKPMLYTVAFLHSTVQ 4266
Score = 192 bits (469), Expect = 2e-47
Identities = 128/408 (31%), Positives = 201/408 (49%), Gaps = 17/408 (4%)
Query: 3745 LEECPHPQFKKLVYVLAFFHAVVQVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFH 3804
L+EC KK V + + +V YGG + + E +F+ F
Sbjct: 4298 LDEC---DIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMFEP--SFC 4352
Query: 3805 FYKDYAFDYVIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIE 3864
FY Y IP D+Y ++I +LP + PEVFGLHPNA+I Y S + +
Sbjct: 4353 FYTGYK----IPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQSNTASAVLETITN 4408
Query: 3865 LQPQTSEAGGAMSREDFIDNIAVDVLSKLPTLYEIWRVRKQ-FEM-NITPTLVVLLQELE 3922
+QP+ S G +RE + ++ D+LSKLP Y V+ + +M ++ + L QE++
Sbjct: 4409 IQPKESGGGVGETREAIVYRLSEDMLSKLPPDYIPHEVKSRLIKMGHLNSMNIFLRQEID 4468
Query: 3923 RFNRLISRMGSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGW 3982
R R+IS + S+LS L+ A+ G I M L + ++++ ++PQ+W+ ++ LG W
Sbjct: 4469 RMQRVISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQLWKRVS-WDSSTLGFW 4527
Query: 3983 MDHFIARTKQYTDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYT-WPLDRSTQFTKV 4041
+ R Q++ W P V W++G P+ +L A Q R + W LD T +V
Sbjct: 4528 FTELLERNAQFSTWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDTVTIHNEV 4587
Query: 4042 TSWVSADEIEERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHK 4101
+ +EI P G Y+ GLY++GA WD G L S PKVL T+LP+++I I
Sbjct: 4588 LR-QTKEEITSPPGEGVYIYGLYMDGAAWDRRNGKLMESTPKVLFTQLPVLHIFAINSTA 4646
Query: 4102 LKLQNTLRTPVYTTSQRRNAMGVGLVFESDLWTTEHCSHWILQGVCLI 4149
K P+Y +R + + +V+ L T HWIL+GV L+
Sbjct: 4647 PKDPKLYVCPIYKKPRRTDLTFITVVY---LRTVLSPDHWILRGVALL 4691
Score = 109 bits (262), Expect = 2e-22
Identities = 55/154 (35%), Positives = 85/154 (55%), Gaps = 2/154 (1%)
Query: 2515 RYYEDLLDYEAIYFLFQEILDEYNE--RNAKMSIVLFEDCLEHLTRTHRILRMDRGNAMX 2572
+ YE + ++ + Q ++NE R + +V F+D + HL + RI+R GNA+
Sbjct: 2964 KIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALL 3023
Query: 2573 XXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMYLQLGVDNKKTVFLFT 2632
+LA+F AG ++F+IT+TR+YN DD+K +Y G D K F+FT
Sbjct: 3024 VGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITFIFT 3083
Query: 2633 AAQILEEGFLEFINNILMIGMIPALFGDDEKDSI 2666
++I +E FLE++NN+L G I LF DE D I
Sbjct: 3084 DSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEI 3117
Score = 96.7 bits (230), Expect = 2e-18
Identities = 74/334 (22%), Positives = 156/334 (46%), Gaps = 22/334 (6%)
Query: 54 ERIFGLELKSIISDPT--QIDDVRKRVKNLVYPIRTVDFSVFVFDNKENWDVIMGDFWNE 111
E I ++ S +S+ T ID + + +N+ ++ + + + + +D DF +
Sbjct: 579 EMITVVQTYSTLSNSTIEGIDIMAIKFRNIYQGVKKKQYDI-LDPRRTEFDTDFLDFMTK 637
Query: 112 VRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEI 171
+ LE + + ++N SFG + SS++AL +L +F + + + +++ + +++ ++ E+
Sbjct: 638 INGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLNI-PCLGLEINHTIERILQYYVAEL 696
Query: 172 TAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMKQPIMKFQKVSELNECEQKKEAF 231
A + + + +PPL RN PP+AG I W R L+ ++ +PI F K S++ K
Sbjct: 697 DATKKLYHSQKDDPPLARNMPPIAGKILWVRQLYRRISEPINYFFKNSDILSSPDGKAVI 756
Query: 232 LQYKAFSKIIKEYEDTKYKEWVQDASLFCDNMMKKNILKVVFKKEDDP----VPQKARGM 287
QY S ++ E+E + W+++ S + + +F + + V + +
Sbjct: 757 RQYNKISYVLVEFEVVYHTAWIREIS-----QLHYALQATLFVRHPETGKLLVNFDPKIL 811
Query: 288 QLTAAGRAHVAKK-KASNTSLKPLDIVNKEIADKRRRDKAL-----MLMRIPGQHYENVR 341
++ + + K + + L + +K ADK L + +P + N+
Sbjct: 812 EVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPSV-FVNLM 870
Query: 342 SP--SSVSLLAKEGLTDVTWRDLTVHKLIQEYNL 373
+P V + ++GLT +TW LT+ QE L
Sbjct: 871 TPKMKKVESVLRQGLTVLTWSSLTLESFFQEVEL 904
Score = 42.7 bits (96), Expect = 0.027
Identities = 22/98 (22%), Positives = 48/98 (48%)
Query: 378 NFDKDLFLVIHEAELMEQLGFDVPSNVRDVAMQKSRLFYELEALSKIIAKYNKNASSLSP 437
NFD + V+ E + M ++ DVP + + +S+L + L ++ Y++ +
Sbjct: 805 NFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPS 864
Query: 438 SETYLMKRHLLDMERHILPGLTRITWTALGINDYIKDI 475
LM + +E + GLT +TW++L + + +++
Sbjct: 865 VFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQEV 902
>AL035690-1|CAI19769.1| 4490|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4490
Score = 849 bits (2100), Expect = 0.0
Identities = 540/1666 (32%), Positives = 877/1666 (52%), Gaps = 82/1666 (4%)
Query: 782 IKGLEDFKLVMATITQVQQMTITAEVKYRGMQEIFHMLKQHGINVTDEDLQFAKSLEASW 841
I+ L+D + M ++ ++ I ++ ++E + +L + + VT E+ + +L S+
Sbjct: 1113 IRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYSF 1172
Query: 842 GSLYQTSLFRGNTLEQTKEKFSKLNVVE-ISNFLKELDDFVEKFDNEGPATVEDDMDRGL 900
L ++ L Q + KF K N++E + F +++ +F E ++ EGP
Sbjct: 1173 NKLQSKAVSVQEDLVQVQPKF-KSNLLESVEVFREDVINFAEAYELEGPMVPNIPPQEAS 1231
Query: 901 LLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNFNRTKADYSAMDQIYKIYKAQKNA 960
++ + D+L + + EQLF P+ D+ ++T+ + + + ++Y +Y ++
Sbjct: 1232 NRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSS 1291
Query: 961 REVWAKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLMLDLKMKQFKGVVPLMVS 1020
+ + LW +++ + + + +F RKLPK ++ L L ++ F PL+
Sbjct: 1292 ISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEM 1351
Query: 1021 LKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMELHKYQDVAEEIVNHAIKELAIE 1080
+ N+AM++RHW + TG FD+ D F L N+ L K++D E+I AIKE IE
Sbjct: 1352 MTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIE 1411
Query: 1081 RGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVVKLDDDSMSLQSMAASQFIGPF 1140
+ V E W N + S + +GE +I+ ++D M L S+ ++++ PF
Sbjct: 1412 AKLTQVIENWTNQNLSFAAFKGKGELL-LKGTESGEIITLMEDSLMVLGSLLSNRYNAPF 1470
Query: 1141 LTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGGDIRTQLPEEAKKFDDIDRAFRK 1200
+Q W ++LS S+IIEEW+ Q W+YLE +FVGGDI QLP+EAK+F +ID+++ K
Sbjct: 1471 KKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIK 1530
Query: 1201 IMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASSDVTRKQINLSQAIAWADR 1260
IM + NV++CC +G + L Q +S + + +K++ + +D
Sbjct: 1531 IMQRAHENPNVINCC-VGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDP 1589
Query: 1261 ASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYVDHTNRPVAAKMISAEGEIMDF 1320
L ++ ++ Q S DNI + + +R +A +IS EGE +
Sbjct: 1590 VLLEILGQASDSHTIQPHLPAVS------DNINEVTFHAKDYDRIMA--VISREGEKIVL 1641
Query: 1321 RNVVYTEGRVEDWMNLVLVEMRHTNKFITKKAIFYYGKNWKVPRTDWILEYQGMVCLAAN 1380
N V +G VE W+ L L++M+ ++ ++ FY + ++ + V L
Sbjct: 1642 DNSVMAKGPVEIWL-LDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGLLGI 1700
Query: 1381 GVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQLDGLVVKVRQDLSSNDRLKFRTITTID 1440
+ WT ++EE LR K +++ M+ Q+ + L+ L+ + DLS DR+KF T+ TI
Sbjct: 1701 QMLWTHDSEEA-LRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIH 1759
Query: 1441 VHARDIIEGFVRDNITEAAEFEWESQLRFYWLKKDDNLWIRQCTGV-FEYGYEYMGLNGR 1499
VH RDI + V+ +I +FEW Q RFY+ K+D + + T V F Y E++G R
Sbjct: 1760 VHQRDIFDDLVKMHIKSPTDFEWLKQSRFYF-KEDLDQTVVSITDVDFIYQNEFLGCTDR 1818
Query: 1500 LVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDF 1559
LVITPLTDR Y+T+ QAL M + D+ + LG VV NC + MDF
Sbjct: 1819 LVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDF 1878
Query: 1560 RAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLKRFTVNTDVLKP 1619
R +G+I GL Q G+WGCFDEFNRI++ VLSV + Q+ + +A + K+F +
Sbjct: 1879 RGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD----- 1933
Query: 1620 SQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTELPESVKALFRPVVCILPDLEMI 1679
G + ++ + GIF+TMNPGYAGR ELPE++K FR V ++PD ++I
Sbjct: 1934 -------------GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQII 1980
Query: 1680 CQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTAVLRMAGKLRRDSPG 1739
++ L S GFL +LA+K VLYK+ EQL+KQ HYD+GLR + +VLR G +R P
Sbjct: 1981 MRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPE 2040
Query: 1740 LSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEKDG 1799
SE+ ++MR LRDMN K V ED PLFL LI DLFPGL+ Y E AV ++ +G
Sbjct: 2041 DSELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEG 2100
Query: 1800 YVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNLGLPTKLTVVNPK 1859
+ P K+VQLYET + RH M +GP+G GKT ++ L+KAQT G P + +NPK
Sbjct: 2101 LINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQTECGRPHREMRMNPK 2160
Query: 1860 ACSVIELYGILDPVTRDWTDGLYSKIFREMNRPAEKNERRYSLFDGDVDALWIENMNSVM 1919
A + +++G LD T DWTDG++S ++R+ + A+K E + + DG VDA+WIEN+NSV+
Sbjct: 2161 AITAPQMFGRLDTATNDWTDGIFSTLWRKTLK-AKKGENIFLILDGPVDAIWIENLNSVL 2219
Query: 1920 DDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGYEPYWERWL 1979
DDNK LTLANG+RI +AP C LLFEV ++ ASPATVSR GMV++ L + P + WL
Sbjct: 2220 DDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWL 2279
Query: 1980 STRSNEEEREQLSGLFEHYVPGAINYIVFGMFGLQQQTPLKTIVPQTPLNLVMQLCYMIS 2039
R+ +E L+ L+E Y+ + P ++ N ++Q ++
Sbjct: 2280 KKRTAQEAAVFLT-LYEKVFEDTYTYMKLNL------NPKMQLL---ECNYIVQSLNLLE 2329
Query: 2040 GLLPNNEDTNMEIDKTVVECVFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVEDNPE 2099
GL+P+ E+ + + + + +F+ + SLGA + R + ++++ E
Sbjct: 2330 GLIPSKEEGGVSCVEHLHK-LFVFGLMWSLGALLELESREKLEAFLRQ----------HE 2378
Query: 2100 KKATTKHFPMGF-PTLYDYCLELTTKLWEAWDWLVPEYEHDRDM--KFPAILVPTVDTLR 2156
K P G T+Y++ + WE W+ + Y + D ++ +ILVP VD +R
Sbjct: 2379 SKLDLPEIPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIR 2437
Query: 2157 LTWLIKIMESIIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMP 2216
+LI ++I +Q T Q ++V+ K + P V + P
Sbjct: 2438 TNFLI---DTIAKQHKAVLLTGE---QGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEP 2491
Query: 2217 ------IVSHNNQCVPSLCST---RVQTL----LSHPLVDTYGTQQPIALLKLLFERKGF 2263
I S+ ++ + S R T+ ++ P+++ +G Q +++ + E +G
Sbjct: 2492 MMFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGM 2551
Query: 2264 YDRGKDLNWKNLKDIGFLAAMGKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSIL 2323
Y K ++ + D+ +AAM GGGRND+ R F+V+N PS ++ I+ I
Sbjct: 2552 YSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIG 2611
Query: 2324 KGHFE---IFPEEIQGIVEKIVQMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMC 2380
G+F+ F +I ++ +V + L++ V++ PTP+KFHYIFNLRDLSRI GM
Sbjct: 2612 CGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGML 2671
Query: 2381 LTHANYFSEKRTVVRCWRNEFTRVICDRLINQQDNELMRGHIQEHV 2426
A + T++ +++E +RVI DR I +D + H+ V
Sbjct: 2672 TIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAV 2717
Score = 652 bits (1612), Expect = 0.0
Identities = 366/1107 (33%), Positives = 591/1107 (53%), Gaps = 26/1107 (2%)
Query: 2682 AKCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKI-PEEFRPIIVEHVVHVHMSV 2740
A+ FPGL++ T+DW WP++AL+AVA+ FL+D + E + +VE + H V
Sbjct: 2961 ARSLKFPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMV 3020
Query: 2741 ARYSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQ 2800
+ + R RR +VTPK Y+ F+ Y + EK FI Q ER+ GL K+ EA+
Sbjct: 3021 SESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASES 3080
Query: 2801 LEDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVE 2860
+ L+ LAV++ +A + + + +L E++ + + + + I E
Sbjct: 3081 VAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSE 3140
Query: 2861 KXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVII--RGIKD 2918
K NDI +R A PP + + +CV+++ + I
Sbjct: 3141 KVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDP 3200
Query: 2919 V-----------SWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLDTM 2966
V SW + +M+ FL +LQ+ D I + V+ ++ + ++
Sbjct: 3201 VTMDPEKSCCKPSWGESLKLMSATGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESA 3260
Query: 2967 QQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQK 3026
+++ GLL + A+ + + A L +D Q
Sbjct: 3261 KKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQA 3320
Query: 3027 TLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSR 3086
LD + +++ AM + +L + D +++ AA L+ GLS E+ RWT+ + +R
Sbjct: 3321 ELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINR 3380
Query: 3087 LIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSG 3146
L+G+ LL T FLSY GPF+ FR ++ + W ++ R IP T + L + +
Sbjct: 3381 LVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARKIPFTENLNLISMLVDPPTIGE 3440
Query: 3147 WNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLR 3206
W +GLP D+LS+QNGI+ T+A+R+PL IDPQTQ TWIK KE +N+L+V S N F
Sbjct: 3441 WGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRT 3500
Query: 3207 QLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTF-VMLGSTEVDYDPNFRMYL 3265
LE ++ G P+L +D++E +DP +DNVLEKN ++SG TF V +G E D F++Y+
Sbjct: 3501 HLEDSLSLGRPLLIEDIHEELDPALDNVLEKNF-IKSGTTFKVKVGDKECDIMDTFKLYI 3559
Query: 3266 TTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANK 3325
TTKL NP F P AK VI++TVT++GLE+QLL V+ E+ +LE +R L+ + + NK
Sbjct: 3560 TTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNK 3619
Query: 3326 SLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRD 3385
+ LED+LL +L+ + G+++D+ L+ L TK AAEV EKL +A T I ++
Sbjct: 3620 RKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQE 3679
Query: 3386 GYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDM 3445
+RP A RGSIL+F++++M+ VN MYQ SL+ +L +F S+ ++ + + KR+ NII+
Sbjct: 3680 EFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEY 3739
Query: 3446 LTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLE-KSARSSP 3504
LT V+ Y G++E HK LF M +K++ V + IKG +L+ K+ P
Sbjct: 3740 LTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKP 3799
Query: 3505 APWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLK 3564
W+ W ++++LS P FA + + I++ + W+ WFD D PE IP+ Y + L
Sbjct: 3800 YRWILDMTWLNLVELSK-LPQ-FAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLD 3857
Query: 3565 PFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPG 3624
L+L+R + DR YI ++ E+Y P +++L+ E++ TP++ LS G
Sbjct: 3858 TCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMG 3917
Query: 3625 SDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFL 3684
SDPT + LA + + + +S+GQGQE A L++ ++ G W++LQNCHL + F+
Sbjct: 3918 SDPTNQIDALAKKLKL---ECRTISMGQGQEVHARKLIQMSMQQGGWVLLQNCHLGLEFM 3974
Query: 3685 RELEKQLELMTKPHPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLNLRNTYFKMR 3741
EL + L +R+W+TT+P FPI +LQ SLK EPP G++ L+ T+ +
Sbjct: 3975 EELLETLITTEASDDSFRVWITTEPHDRFPITLLQTSLKFTNEPPQGVRAGLKRTFAGIN 4034
Query: 3742 ARALEECPHPQFKKLVYVLAFFHAVVQ 3768
L+ P +K ++Y +AF H+ VQ
Sbjct: 4035 QDLLDISNLPMWKPMLYTVAFLHSTVQ 4061
Score = 192 bits (469), Expect = 2e-47
Identities = 128/408 (31%), Positives = 201/408 (49%), Gaps = 17/408 (4%)
Query: 3745 LEECPHPQFKKLVYVLAFFHAVVQVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFH 3804
L+EC KK V + + +V YGG + + E +F+ F
Sbjct: 4093 LDEC---DIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMFEP--SFC 4147
Query: 3805 FYKDYAFDYVIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIE 3864
FY Y IP D+Y ++I +LP + PEVFGLHPNA+I Y S + +
Sbjct: 4148 FYTGYK----IPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQSNTASAVLETITN 4203
Query: 3865 LQPQTSEAGGAMSREDFIDNIAVDVLSKLPTLYEIWRVRKQ-FEM-NITPTLVVLLQELE 3922
+QP+ S G +RE + ++ D+LSKLP Y V+ + +M ++ + L QE++
Sbjct: 4204 IQPKESGGGVGETREAIVYRLSEDMLSKLPPDYIPHEVKSRLIKMGHLNSMNIFLRQEID 4263
Query: 3923 RFNRLISRMGSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGW 3982
R R+IS + S+LS L+ A+ G I M L + ++++ ++PQ+W+ ++ LG W
Sbjct: 4264 RMQRVISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQLWKRVS-WDSSTLGFW 4322
Query: 3983 MDHFIARTKQYTDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYT-WPLDRSTQFTKV 4041
+ R Q++ W P V W++G P+ +L A Q R + W LD T +V
Sbjct: 4323 FTELLERNAQFSTWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDTVTIHNEV 4382
Query: 4042 TSWVSADEIEERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHK 4101
+ +EI P G Y+ GLY++GA WD G L S PKVL T+LP+++I I
Sbjct: 4383 LR-QTKEEITSPPGEGVYIYGLYMDGAAWDRRNGKLMESTPKVLFTQLPVLHIFAINSTA 4441
Query: 4102 LKLQNTLRTPVYTTSQRRNAMGVGLVFESDLWTTEHCSHWILQGVCLI 4149
K P+Y +R + + +V+ L T HWIL+GV L+
Sbjct: 4442 PKDPKLYVCPIYKKPRRTDLTFITVVY---LRTVLSPDHWILRGVALL 4486
Score = 109 bits (262), Expect = 2e-22
Identities = 55/154 (35%), Positives = 85/154 (55%), Gaps = 2/154 (1%)
Query: 2515 RYYEDLLDYEAIYFLFQEILDEYNE--RNAKMSIVLFEDCLEHLTRTHRILRMDRGNAMX 2572
+ YE + ++ + Q ++NE R + +V F+D + HL + RI+R GNA+
Sbjct: 2759 KIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALL 2818
Query: 2573 XXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMYLQLGVDNKKTVFLFT 2632
+LA+F AG ++F+IT+TR+YN DD+K +Y G D K F+FT
Sbjct: 2819 VGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITFIFT 2878
Query: 2633 AAQILEEGFLEFINNILMIGMIPALFGDDEKDSI 2666
++I +E FLE++NN+L G I LF DE D I
Sbjct: 2879 DSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEI 2912
Score = 96.7 bits (230), Expect = 2e-18
Identities = 74/334 (22%), Positives = 156/334 (46%), Gaps = 22/334 (6%)
Query: 54 ERIFGLELKSIISDPT--QIDDVRKRVKNLVYPIRTVDFSVFVFDNKENWDVIMGDFWNE 111
E I ++ S +S+ T ID + + +N+ ++ + + + + +D DF +
Sbjct: 374 EMITVVQTYSTLSNSTIEGIDIMAIKFRNIYQGVKKKQYDI-LDPRRTEFDTDFLDFMTK 432
Query: 112 VRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEI 171
+ LE + + ++N SFG + SS++AL +L +F + + + +++ + +++ ++ E+
Sbjct: 433 INGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLNI-PCLGLEINHTIERILQYYVAEL 491
Query: 172 TAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMKQPIMKFQKVSELNECEQKKEAF 231
A + + + +PPL RN PP+AG I W R L+ ++ +PI F K S++ K
Sbjct: 492 DATKKLYHSQKDDPPLARNMPPIAGKILWVRQLYRRISEPINYFFKNSDILSSPDGKAVI 551
Query: 232 LQYKAFSKIIKEYEDTKYKEWVQDASLFCDNMMKKNILKVVFKKEDDP----VPQKARGM 287
QY S ++ E+E + W+++ S + + +F + + V + +
Sbjct: 552 RQYNKISYVLVEFEVVYHTAWIREIS-----QLHYALQATLFVRHPETGKLLVNFDPKIL 606
Query: 288 QLTAAGRAHVAKK-KASNTSLKPLDIVNKEIADKRRRDKAL-----MLMRIPGQHYENVR 341
++ + + K + + L + +K ADK L + +P + N+
Sbjct: 607 EVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPSV-FVNLM 665
Query: 342 SP--SSVSLLAKEGLTDVTWRDLTVHKLIQEYNL 373
+P V + ++GLT +TW LT+ QE L
Sbjct: 666 TPKMKKVESVLRQGLTVLTWSSLTLESFFQEVEL 699
Score = 42.7 bits (96), Expect = 0.027
Identities = 22/98 (22%), Positives = 48/98 (48%)
Query: 378 NFDKDLFLVIHEAELMEQLGFDVPSNVRDVAMQKSRLFYELEALSKIIAKYNKNASSLSP 437
NFD + V+ E + M ++ DVP + + +S+L + L ++ Y++ +
Sbjct: 600 NFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPS 659
Query: 438 SETYLMKRHLLDMERHILPGLTRITWTALGINDYIKDI 475
LM + +E + GLT +TW++L + + +++
Sbjct: 660 VFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQEV 697
>AL035555-4|CAI19822.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 849 bits (2100), Expect = 0.0
Identities = 540/1666 (32%), Positives = 877/1666 (52%), Gaps = 82/1666 (4%)
Query: 782 IKGLEDFKLVMATITQVQQMTITAEVKYRGMQEIFHMLKQHGINVTDEDLQFAKSLEASW 841
I+ L+D + M ++ ++ I ++ ++E + +L + + VT E+ + +L S+
Sbjct: 1318 IRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYSF 1377
Query: 842 GSLYQTSLFRGNTLEQTKEKFSKLNVVE-ISNFLKELDDFVEKFDNEGPATVEDDMDRGL 900
L ++ L Q + KF K N++E + F +++ +F E ++ EGP
Sbjct: 1378 NKLQSKAVSVQEDLVQVQPKF-KSNLLESVEVFREDVINFAEAYELEGPMVPNIPPQEAS 1436
Query: 901 LLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNFNRTKADYSAMDQIYKIYKAQKNA 960
++ + D+L + + EQLF P+ D+ ++T+ + + + ++Y +Y ++
Sbjct: 1437 NRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSS 1496
Query: 961 REVWAKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLMLDLKMKQFKGVVPLMVS 1020
+ + LW +++ + + + +F RKLPK ++ L L ++ F PL+
Sbjct: 1497 ISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEM 1556
Query: 1021 LKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMELHKYQDVAEEIVNHAIKELAIE 1080
+ N+AM++RHW + TG FD+ D F L N+ L K++D E+I AIKE IE
Sbjct: 1557 MTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIE 1616
Query: 1081 RGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVVKLDDDSMSLQSMAASQFIGPF 1140
+ V E W N + S + +GE +I+ ++D M L S+ ++++ PF
Sbjct: 1617 AKLTQVIENWTNQNLSFAAFKGKGELL-LKGTESGEIITLMEDSLMVLGSLLSNRYNAPF 1675
Query: 1141 LTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGGDIRTQLPEEAKKFDDIDRAFRK 1200
+Q W ++LS S+IIEEW+ Q W+YLE +FVGGDI QLP+EAK+F +ID+++ K
Sbjct: 1676 KKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIK 1735
Query: 1201 IMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASSDVTRKQINLSQAIAWADR 1260
IM + NV++CC +G + L Q +S + + +K++ + +D
Sbjct: 1736 IMQRAHENPNVINCC-VGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDP 1794
Query: 1261 ASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYVDHTNRPVAAKMISAEGEIMDF 1320
L ++ ++ Q S DNI + + +R +A +IS EGE +
Sbjct: 1795 VLLEILGQASDSHTIQPHLPAVS------DNINEVTFHAKDYDRIMA--VISREGEKIVL 1846
Query: 1321 RNVVYTEGRVEDWMNLVLVEMRHTNKFITKKAIFYYGKNWKVPRTDWILEYQGMVCLAAN 1380
N V +G VE W+ L L++M+ ++ ++ FY + ++ + V L
Sbjct: 1847 DNSVMAKGPVEIWL-LDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGLLGI 1905
Query: 1381 GVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQLDGLVVKVRQDLSSNDRLKFRTITTID 1440
+ WT ++EE LR K +++ M+ Q+ + L+ L+ + DLS DR+KF T+ TI
Sbjct: 1906 QMLWTHDSEEA-LRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIH 1964
Query: 1441 VHARDIIEGFVRDNITEAAEFEWESQLRFYWLKKDDNLWIRQCTGV-FEYGYEYMGLNGR 1499
VH RDI + V+ +I +FEW Q RFY+ K+D + + T V F Y E++G R
Sbjct: 1965 VHQRDIFDDLVKMHIKSPTDFEWLKQSRFYF-KEDLDQTVVSITDVDFIYQNEFLGCTDR 2023
Query: 1500 LVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDF 1559
LVITPLTDR Y+T+ QAL M + D+ + LG VV NC + MDF
Sbjct: 2024 LVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDF 2083
Query: 1560 RAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLKRFTVNTDVLKP 1619
R +G+I GL Q G+WGCFDEFNRI++ VLSV + Q+ + +A + K+F +
Sbjct: 2084 RGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD----- 2138
Query: 1620 SQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTELPESVKALFRPVVCILPDLEMI 1679
G + ++ + GIF+TMNPGYAGR ELPE++K FR V ++PD ++I
Sbjct: 2139 -------------GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQII 2185
Query: 1680 CQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTAVLRMAGKLRRDSPG 1739
++ L S GFL +LA+K VLYK+ EQL+KQ HYD+GLR + +VLR G +R P
Sbjct: 2186 MRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPE 2245
Query: 1740 LSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEKDG 1799
SE+ ++MR LRDMN K V ED PLFL LI DLFPGL+ Y E AV ++ +G
Sbjct: 2246 DSELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEG 2305
Query: 1800 YVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNLGLPTKLTVVNPK 1859
+ P K+VQLYET + RH M +GP+G GKT ++ L+KAQT G P + +NPK
Sbjct: 2306 LINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQTECGRPHREMRMNPK 2365
Query: 1860 ACSVIELYGILDPVTRDWTDGLYSKIFREMNRPAEKNERRYSLFDGDVDALWIENMNSVM 1919
A + +++G LD T DWTDG++S ++R+ + A+K E + + DG VDA+WIEN+NSV+
Sbjct: 2366 AITAPQMFGRLDTATNDWTDGIFSTLWRKTLK-AKKGENIFLILDGPVDAIWIENLNSVL 2424
Query: 1920 DDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGYEPYWERWL 1979
DDNK LTLANG+RI +AP C LLFEV ++ ASPATVSR GMV++ L + P + WL
Sbjct: 2425 DDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWL 2484
Query: 1980 STRSNEEEREQLSGLFEHYVPGAINYIVFGMFGLQQQTPLKTIVPQTPLNLVMQLCYMIS 2039
R+ +E L+ L+E Y+ + P ++ N ++Q ++
Sbjct: 2485 KKRTAQEAAVFLT-LYEKVFEDTYTYMKLNL------NPKMQLL---ECNYIVQSLNLLE 2534
Query: 2040 GLLPNNEDTNMEIDKTVVECVFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVEDNPE 2099
GL+P+ E+ + + + + +F+ + SLGA + R + ++++ E
Sbjct: 2535 GLIPSKEEGGVSCVEHLHK-LFVFGLMWSLGALLELESREKLEAFLRQ----------HE 2583
Query: 2100 KKATTKHFPMGF-PTLYDYCLELTTKLWEAWDWLVPEYEHDRDM--KFPAILVPTVDTLR 2156
K P G T+Y++ + WE W+ + Y + D ++ +ILVP VD +R
Sbjct: 2584 SKLDLPEIPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIR 2642
Query: 2157 LTWLIKIMESIIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMP 2216
+LI ++I +Q T Q ++V+ K + P V + P
Sbjct: 2643 TNFLI---DTIAKQHKAVLLTGE---QGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEP 2696
Query: 2217 ------IVSHNNQCVPSLCST---RVQTL----LSHPLVDTYGTQQPIALLKLLFERKGF 2263
I S+ ++ + S R T+ ++ P+++ +G Q +++ + E +G
Sbjct: 2697 MMFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGM 2756
Query: 2264 YDRGKDLNWKNLKDIGFLAAMGKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSIL 2323
Y K ++ + D+ +AAM GGGRND+ R F+V+N PS ++ I+ I
Sbjct: 2757 YSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIG 2816
Query: 2324 KGHFE---IFPEEIQGIVEKIVQMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMC 2380
G+F+ F +I ++ +V + L++ V++ PTP+KFHYIFNLRDLSRI GM
Sbjct: 2817 CGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGML 2876
Query: 2381 LTHANYFSEKRTVVRCWRNEFTRVICDRLINQQDNELMRGHIQEHV 2426
A + T++ +++E +RVI DR I +D + H+ V
Sbjct: 2877 TIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAV 2922
Score = 652 bits (1612), Expect = 0.0
Identities = 366/1107 (33%), Positives = 591/1107 (53%), Gaps = 26/1107 (2%)
Query: 2682 AKCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKI-PEEFRPIIVEHVVHVHMSV 2740
A+ FPGL++ T+DW WP++AL+AVA+ FL+D + E + +VE + H V
Sbjct: 3166 ARSLKFPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMV 3225
Query: 2741 ARYSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQ 2800
+ + R RR +VTPK Y+ F+ Y + EK FI Q ER+ GL K+ EA+
Sbjct: 3226 SESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASES 3285
Query: 2801 LEDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVE 2860
+ L+ LAV++ +A + + + +L E++ + + + + I E
Sbjct: 3286 VAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSE 3345
Query: 2861 KXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVII--RGIKD 2918
K NDI +R A PP + + +CV+++ + I
Sbjct: 3346 KVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDP 3405
Query: 2919 V-----------SWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLDTM 2966
V SW + +M+ FL +LQ+ D I + V+ ++ + ++
Sbjct: 3406 VTMDPEKSCCKPSWGESLKLMSATGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESA 3465
Query: 2967 QQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQK 3026
+++ GLL + A+ + + A L +D Q
Sbjct: 3466 KKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQA 3525
Query: 3027 TLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSR 3086
LD + +++ AM + +L + D +++ AA L+ GLS E+ RWT+ + +R
Sbjct: 3526 ELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINR 3585
Query: 3087 LIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSG 3146
L+G+ LL T FLSY GPF+ FR ++ + W ++ R IP T + L + +
Sbjct: 3586 LVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARKIPFTENLNLISMLVDPPTIGE 3645
Query: 3147 WNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLR 3206
W +GLP D+LS+QNGI+ T+A+R+PL IDPQTQ TWIK KE +N+L+V S N F
Sbjct: 3646 WGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRT 3705
Query: 3207 QLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTF-VMLGSTEVDYDPNFRMYL 3265
LE ++ G P+L +D++E +DP +DNVLEKN ++SG TF V +G E D F++Y+
Sbjct: 3706 HLEDSLSLGRPLLIEDIHEELDPALDNVLEKNF-IKSGTTFKVKVGDKECDIMDTFKLYI 3764
Query: 3266 TTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANK 3325
TTKL NP F P AK VI++TVT++GLE+QLL V+ E+ +LE +R L+ + + NK
Sbjct: 3765 TTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNK 3824
Query: 3326 SLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRD 3385
+ LED+LL +L+ + G+++D+ L+ L TK AAEV EKL +A T I ++
Sbjct: 3825 RKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQE 3884
Query: 3386 GYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDM 3445
+RP A RGSIL+F++++M+ VN MYQ SL+ +L +F S+ ++ + + KR+ NII+
Sbjct: 3885 EFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEY 3944
Query: 3446 LTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLE-KSARSSP 3504
LT V+ Y G++E HK LF M +K++ V + IKG +L+ K+ P
Sbjct: 3945 LTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKP 4004
Query: 3505 APWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLK 3564
W+ W ++++LS P FA + + I++ + W+ WFD D PE IP+ Y + L
Sbjct: 4005 YRWILDMTWLNLVELSK-LPQ-FAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLD 4062
Query: 3565 PFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPG 3624
L+L+R + DR YI ++ E+Y P +++L+ E++ TP++ LS G
Sbjct: 4063 TCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMG 4122
Query: 3625 SDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFL 3684
SDPT + LA + + + +S+GQGQE A L++ ++ G W++LQNCHL + F+
Sbjct: 4123 SDPTNQIDALAKKLKL---ECRTISMGQGQEVHARKLIQMSMQQGGWVLLQNCHLGLEFM 4179
Query: 3685 RELEKQLELMTKPHPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLNLRNTYFKMR 3741
EL + L +R+W+TT+P FPI +LQ SLK EPP G++ L+ T+ +
Sbjct: 4180 EELLETLITTEASDDSFRVWITTEPHDRFPITLLQTSLKFTNEPPQGVRAGLKRTFAGIN 4239
Query: 3742 ARALEECPHPQFKKLVYVLAFFHAVVQ 3768
L+ P +K ++Y +AF H+ VQ
Sbjct: 4240 QDLLDISNLPMWKPMLYTVAFLHSTVQ 4266
Score = 192 bits (469), Expect = 2e-47
Identities = 128/408 (31%), Positives = 201/408 (49%), Gaps = 17/408 (4%)
Query: 3745 LEECPHPQFKKLVYVLAFFHAVVQVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFH 3804
L+EC KK V + + +V YGG + + E +F+ F
Sbjct: 4298 LDEC---DIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMFEP--SFC 4352
Query: 3805 FYKDYAFDYVIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIE 3864
FY Y IP D+Y ++I +LP + PEVFGLHPNA+I Y S + +
Sbjct: 4353 FYTGYK----IPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQSNTASAVLETITN 4408
Query: 3865 LQPQTSEAGGAMSREDFIDNIAVDVLSKLPTLYEIWRVRKQ-FEM-NITPTLVVLLQELE 3922
+QP+ S G +RE + ++ D+LSKLP Y V+ + +M ++ + L QE++
Sbjct: 4409 IQPKESGGGVGETREAIVYRLSEDMLSKLPPDYIPHEVKSRLIKMGHLNSMNIFLRQEID 4468
Query: 3923 RFNRLISRMGSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGW 3982
R R+IS + S+LS L+ A+ G I M L + ++++ ++PQ+W+ ++ LG W
Sbjct: 4469 RMQRVISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQLWKRVS-WDSSTLGFW 4527
Query: 3983 MDHFIARTKQYTDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYT-WPLDRSTQFTKV 4041
+ R Q++ W P V W++G P+ +L A Q R + W LD T +V
Sbjct: 4528 FTELLERNAQFSTWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDTVTIHNEV 4587
Query: 4042 TSWVSADEIEERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHK 4101
+ +EI P G Y+ GLY++GA WD G L S PKVL T+LP+++I I
Sbjct: 4588 LR-QTKEEITSPPGEGVYIYGLYMDGAAWDRRNGKLMESTPKVLFTQLPVLHIFAINSTA 4646
Query: 4102 LKLQNTLRTPVYTTSQRRNAMGVGLVFESDLWTTEHCSHWILQGVCLI 4149
K P+Y +R + + +V+ L T HWIL+GV L+
Sbjct: 4647 PKDPKLYVCPIYKKPRRTDLTFITVVY---LRTVLSPDHWILRGVALL 4691
Score = 109 bits (262), Expect = 2e-22
Identities = 55/154 (35%), Positives = 85/154 (55%), Gaps = 2/154 (1%)
Query: 2515 RYYEDLLDYEAIYFLFQEILDEYNE--RNAKMSIVLFEDCLEHLTRTHRILRMDRGNAMX 2572
+ YE + ++ + Q ++NE R + +V F+D + HL + RI+R GNA+
Sbjct: 2964 KIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALL 3023
Query: 2573 XXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMYLQLGVDNKKTVFLFT 2632
+LA+F AG ++F+IT+TR+YN DD+K +Y G D K F+FT
Sbjct: 3024 VGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITFIFT 3083
Query: 2633 AAQILEEGFLEFINNILMIGMIPALFGDDEKDSI 2666
++I +E FLE++NN+L G I LF DE D I
Sbjct: 3084 DSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEI 3117
Score = 96.7 bits (230), Expect = 2e-18
Identities = 74/334 (22%), Positives = 156/334 (46%), Gaps = 22/334 (6%)
Query: 54 ERIFGLELKSIISDPT--QIDDVRKRVKNLVYPIRTVDFSVFVFDNKENWDVIMGDFWNE 111
E I ++ S +S+ T ID + + +N+ ++ + + + + +D DF +
Sbjct: 579 EMITVVQTYSTLSNSTIEGIDIMAIKFRNIYQGVKKKQYDI-LDPRRTEFDTDFLDFMTK 637
Query: 112 VRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEI 171
+ LE + + ++N SFG + SS++AL +L +F + + + +++ + +++ ++ E+
Sbjct: 638 INGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLNI-PCLGLEINHTIERILQYYVAEL 696
Query: 172 TAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMKQPIMKFQKVSELNECEQKKEAF 231
A + + + +PPL RN PP+AG I W R L+ ++ +PI F K S++ K
Sbjct: 697 DATKKLYHSQKDDPPLARNMPPIAGKILWVRQLYRRISEPINYFFKNSDILSSPDGKAVI 756
Query: 232 LQYKAFSKIIKEYEDTKYKEWVQDASLFCDNMMKKNILKVVFKKEDDP----VPQKARGM 287
QY S ++ E+E + W+++ S + + +F + + V + +
Sbjct: 757 RQYNKISYVLVEFEVVYHTAWIREIS-----QLHYALQATLFVRHPETGKLLVNFDPKIL 811
Query: 288 QLTAAGRAHVAKK-KASNTSLKPLDIVNKEIADKRRRDKAL-----MLMRIPGQHYENVR 341
++ + + K + + L + +K ADK L + +P + N+
Sbjct: 812 EVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPSV-FVNLM 870
Query: 342 SP--SSVSLLAKEGLTDVTWRDLTVHKLIQEYNL 373
+P V + ++GLT +TW LT+ QE L
Sbjct: 871 TPKMKKVESVLRQGLTVLTWSSLTLESFFQEVEL 904
Score = 42.7 bits (96), Expect = 0.027
Identities = 22/98 (22%), Positives = 48/98 (48%)
Query: 378 NFDKDLFLVIHEAELMEQLGFDVPSNVRDVAMQKSRLFYELEALSKIIAKYNKNASSLSP 437
NFD + V+ E + M ++ DVP + + +S+L + L ++ Y++ +
Sbjct: 805 NFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPS 864
Query: 438 SETYLMKRHLLDMERHILPGLTRITWTALGINDYIKDI 475
LM + +E + GLT +TW++L + + +++
Sbjct: 865 VFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQEV 902
>AL035555-3|CAI19821.1| 4176|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4176
Score = 849 bits (2100), Expect = 0.0
Identities = 540/1666 (32%), Positives = 877/1666 (52%), Gaps = 82/1666 (4%)
Query: 782 IKGLEDFKLVMATITQVQQMTITAEVKYRGMQEIFHMLKQHGINVTDEDLQFAKSLEASW 841
I+ L+D + M ++ ++ I ++ ++E + +L + + VT E+ + +L S+
Sbjct: 1318 IRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYSF 1377
Query: 842 GSLYQTSLFRGNTLEQTKEKFSKLNVVE-ISNFLKELDDFVEKFDNEGPATVEDDMDRGL 900
L ++ L Q + KF K N++E + F +++ +F E ++ EGP
Sbjct: 1378 NKLQSKAVSVQEDLVQVQPKF-KSNLLESVEVFREDVINFAEAYELEGPMVPNIPPQEAS 1436
Query: 901 LLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNFNRTKADYSAMDQIYKIYKAQKNA 960
++ + D+L + + EQLF P+ D+ ++T+ + + + ++Y +Y ++
Sbjct: 1437 NRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSS 1496
Query: 961 REVWAKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLMLDLKMKQFKGVVPLMVS 1020
+ + LW +++ + + + +F RKLPK ++ L L ++ F PL+
Sbjct: 1497 ISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEM 1556
Query: 1021 LKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMELHKYQDVAEEIVNHAIKELAIE 1080
+ N+AM++RHW + TG FD+ D F L N+ L K++D E+I AIKE IE
Sbjct: 1557 MTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIE 1616
Query: 1081 RGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVVKLDDDSMSLQSMAASQFIGPF 1140
+ V E W N + S + +GE +I+ ++D M L S+ ++++ PF
Sbjct: 1617 AKLTQVIENWTNQNLSFAAFKGKGELL-LKGTESGEIITLMEDSLMVLGSLLSNRYNAPF 1675
Query: 1141 LTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGGDIRTQLPEEAKKFDDIDRAFRK 1200
+Q W ++LS S+IIEEW+ Q W+YLE +FVGGDI QLP+EAK+F +ID+++ K
Sbjct: 1676 KKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIK 1735
Query: 1201 IMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASSDVTRKQINLSQAIAWADR 1260
IM + NV++CC +G + L Q +S + + +K++ + +D
Sbjct: 1736 IMQRAHENPNVINCC-VGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDP 1794
Query: 1261 ASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYVDHTNRPVAAKMISAEGEIMDF 1320
L ++ ++ Q S DNI + + +R +A +IS EGE +
Sbjct: 1795 VLLEILGQASDSHTIQPHLPAVS------DNINEVTFHAKDYDRIMA--VISREGEKIVL 1846
Query: 1321 RNVVYTEGRVEDWMNLVLVEMRHTNKFITKKAIFYYGKNWKVPRTDWILEYQGMVCLAAN 1380
N V +G VE W+ L L++M+ ++ ++ FY + ++ + V L
Sbjct: 1847 DNSVMAKGPVEIWL-LDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGLLGI 1905
Query: 1381 GVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQLDGLVVKVRQDLSSNDRLKFRTITTID 1440
+ WT ++EE LR K +++ M+ Q+ + L+ L+ + DLS DR+KF T+ TI
Sbjct: 1906 QMLWTHDSEEA-LRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIH 1964
Query: 1441 VHARDIIEGFVRDNITEAAEFEWESQLRFYWLKKDDNLWIRQCTGV-FEYGYEYMGLNGR 1499
VH RDI + V+ +I +FEW Q RFY+ K+D + + T V F Y E++G R
Sbjct: 1965 VHQRDIFDDLVKMHIKSPTDFEWLKQSRFYF-KEDLDQTVVSITDVDFIYQNEFLGCTDR 2023
Query: 1500 LVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDF 1559
LVITPLTDR Y+T+ QAL M + D+ + LG VV NC + MDF
Sbjct: 2024 LVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDF 2083
Query: 1560 RAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLKRFTVNTDVLKP 1619
R +G+I GL Q G+WGCFDEFNRI++ VLSV + Q+ + +A + K+F +
Sbjct: 2084 RGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD----- 2138
Query: 1620 SQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTELPESVKALFRPVVCILPDLEMI 1679
G + ++ + GIF+TMNPGYAGR ELPE++K FR V ++PD ++I
Sbjct: 2139 -------------GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQII 2185
Query: 1680 CQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTAVLRMAGKLRRDSPG 1739
++ L S GFL +LA+K VLYK+ EQL+KQ HYD+GLR + +VLR G +R P
Sbjct: 2186 MRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPE 2245
Query: 1740 LSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEKDG 1799
SE+ ++MR LRDMN K V ED PLFL LI DLFPGL+ Y E AV ++ +G
Sbjct: 2246 DSELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEG 2305
Query: 1800 YVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNLGLPTKLTVVNPK 1859
+ P K+VQLYET + RH M +GP+G GKT ++ L+KAQT G P + +NPK
Sbjct: 2306 LINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQTECGRPHREMRMNPK 2365
Query: 1860 ACSVIELYGILDPVTRDWTDGLYSKIFREMNRPAEKNERRYSLFDGDVDALWIENMNSVM 1919
A + +++G LD T DWTDG++S ++R+ + A+K E + + DG VDA+WIEN+NSV+
Sbjct: 2366 AITAPQMFGRLDTATNDWTDGIFSTLWRKTLK-AKKGENIFLILDGPVDAIWIENLNSVL 2424
Query: 1920 DDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGYEPYWERWL 1979
DDNK LTLANG+RI +AP C LLFEV ++ ASPATVSR GMV++ L + P + WL
Sbjct: 2425 DDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWL 2484
Query: 1980 STRSNEEEREQLSGLFEHYVPGAINYIVFGMFGLQQQTPLKTIVPQTPLNLVMQLCYMIS 2039
R+ +E L+ L+E Y+ + P ++ N ++Q ++
Sbjct: 2485 KKRTAQEAAVFLT-LYEKVFEDTYTYMKLNL------NPKMQLL---ECNYIVQSLNLLE 2534
Query: 2040 GLLPNNEDTNMEIDKTVVECVFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVEDNPE 2099
GL+P+ E+ + + + + +F+ + SLGA + R + ++++ E
Sbjct: 2535 GLIPSKEEGGVSCVEHLHK-LFVFGLMWSLGALLELESREKLEAFLRQ----------HE 2583
Query: 2100 KKATTKHFPMGF-PTLYDYCLELTTKLWEAWDWLVPEYEHDRDM--KFPAILVPTVDTLR 2156
K P G T+Y++ + WE W+ + Y + D ++ +ILVP VD +R
Sbjct: 2584 SKLDLPEIPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIR 2642
Query: 2157 LTWLIKIMESIIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMP 2216
+LI ++I +Q T Q ++V+ K + P V + P
Sbjct: 2643 TNFLI---DTIAKQHKAVLLTGE---QGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEP 2696
Query: 2217 ------IVSHNNQCVPSLCST---RVQTL----LSHPLVDTYGTQQPIALLKLLFERKGF 2263
I S+ ++ + S R T+ ++ P+++ +G Q +++ + E +G
Sbjct: 2697 MMFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGM 2756
Query: 2264 YDRGKDLNWKNLKDIGFLAAMGKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSIL 2323
Y K ++ + D+ +AAM GGGRND+ R F+V+N PS ++ I+ I
Sbjct: 2757 YSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIG 2816
Query: 2324 KGHFE---IFPEEIQGIVEKIVQMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMC 2380
G+F+ F +I ++ +V + L++ V++ PTP+KFHYIFNLRDLSRI GM
Sbjct: 2817 CGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGML 2876
Query: 2381 LTHANYFSEKRTVVRCWRNEFTRVICDRLINQQDNELMRGHIQEHV 2426
A + T++ +++E +RVI DR I +D + H+ V
Sbjct: 2877 TIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAV 2922
Score = 572 bits (1412), Expect = e-162
Identities = 326/999 (32%), Positives = 528/999 (52%), Gaps = 23/999 (2%)
Query: 2682 AKCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKI-PEEFRPIIVEHVVHVHMSV 2740
A+ FPGL++ T+DW WP++AL+AVA+ FL+D + E + +VE + H V
Sbjct: 3166 ARSLKFPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMV 3225
Query: 2741 ARYSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQ 2800
+ + R RR +VTPK Y+ F+ Y + EK FI Q ER+ GL K+ EA+
Sbjct: 3226 SESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASES 3285
Query: 2801 LEDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVE 2860
+ L+ LAV++ +A + + + +L E++ + + + + I E
Sbjct: 3286 VAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSE 3345
Query: 2861 KXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVII--RGIKD 2918
K NDI +R A PP + + +CV+++ + I
Sbjct: 3346 KVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDP 3405
Query: 2919 V-----------SWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLDTM 2966
V SW + +M+ FL +LQ+ D I + V+ ++ + ++
Sbjct: 3406 VTMDPEKSCCKPSWGESLKLMSATGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESA 3465
Query: 2967 QQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQK 3026
+++ GLL + A+ + + A L +D Q
Sbjct: 3466 KKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQA 3525
Query: 3027 TLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSR 3086
LD + +++ AM + +L + D +++ AA L+ GLS E+ RWT+ + +R
Sbjct: 3526 ELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINR 3585
Query: 3087 LIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSG 3146
L+G+ LL T FLSY GPF+ FR ++ + W ++ R IP T + L + +
Sbjct: 3586 LVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARKIPFTENLNLISMLVDPPTIGE 3645
Query: 3147 WNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLR 3206
W +GLP D+LS+QNGI+ T+A+R+PL IDPQTQ TWIK KE +N+L+V S N F
Sbjct: 3646 WGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRT 3705
Query: 3207 QLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTF-VMLGSTEVDYDPNFRMYL 3265
LE ++ G P+L +D++E +DP +DNVLEKN ++SG TF V +G E D F++Y+
Sbjct: 3706 HLEDSLSLGRPLLIEDIHEELDPALDNVLEKNF-IKSGTTFKVKVGDKECDIMDTFKLYI 3764
Query: 3266 TTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANK 3325
TTKL NP F P AK VI++TVT++GLE+QLL V+ E+ +LE +R L+ + + NK
Sbjct: 3765 TTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNK 3824
Query: 3326 SLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRD 3385
+ LED+LL +L+ + G+++D+ L+ L TK AAEV EKL +A T I ++
Sbjct: 3825 RKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQE 3884
Query: 3386 GYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDM 3445
+RP A RGSIL+F++++M+ VN MYQ SL+ +L +F S+ ++ + + KR+ NII+
Sbjct: 3885 EFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEY 3944
Query: 3446 LTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLE-KSARSSP 3504
LT V+ Y G++E HK LF M +K++ V + IKG +L+ K+ P
Sbjct: 3945 LTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKP 4004
Query: 3505 APWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLK 3564
W+ W ++++LS P FA + + I++ + W+ WFD D PE IP+ Y + L
Sbjct: 4005 YRWILDMTWLNLVELSK-LPQ-FAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLD 4062
Query: 3565 PFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPG 3624
L+L+R + DR YI ++ E+Y P +++L+ E++ TP++ LS G
Sbjct: 4063 TCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMG 4122
Query: 3625 SDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLE 3663
SDPT + LA + + + +S+GQGQE A L++
Sbjct: 4123 SDPTNQIDALAKKLKL---ECRTISMGQGQEVHARKLIQ 4158
Score = 109 bits (262), Expect = 2e-22
Identities = 55/154 (35%), Positives = 85/154 (55%), Gaps = 2/154 (1%)
Query: 2515 RYYEDLLDYEAIYFLFQEILDEYNE--RNAKMSIVLFEDCLEHLTRTHRILRMDRGNAMX 2572
+ YE + ++ + Q ++NE R + +V F+D + HL + RI+R GNA+
Sbjct: 2964 KIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALL 3023
Query: 2573 XXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMYLQLGVDNKKTVFLFT 2632
+LA+F AG ++F+IT+TR+YN DD+K +Y G D K F+FT
Sbjct: 3024 VGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITFIFT 3083
Query: 2633 AAQILEEGFLEFINNILMIGMIPALFGDDEKDSI 2666
++I +E FLE++NN+L G I LF DE D I
Sbjct: 3084 DSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEI 3117
Score = 96.7 bits (230), Expect = 2e-18
Identities = 74/334 (22%), Positives = 156/334 (46%), Gaps = 22/334 (6%)
Query: 54 ERIFGLELKSIISDPT--QIDDVRKRVKNLVYPIRTVDFSVFVFDNKENWDVIMGDFWNE 111
E I ++ S +S+ T ID + + +N+ ++ + + + + +D DF +
Sbjct: 579 EMITVVQTYSTLSNSTIEGIDIMAIKFRNIYQGVKKKQYDI-LDPRRTEFDTDFLDFMTK 637
Query: 112 VRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEI 171
+ LE + + ++N SFG + SS++AL +L +F + + + +++ + +++ ++ E+
Sbjct: 638 INGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLNI-PCLGLEINHTIERILQYYVAEL 696
Query: 172 TAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMKQPIMKFQKVSELNECEQKKEAF 231
A + + + +PPL RN PP+AG I W R L+ ++ +PI F K S++ K
Sbjct: 697 DATKKLYHSQKDDPPLARNMPPIAGKILWVRQLYRRISEPINYFFKNSDILSSPDGKAVI 756
Query: 232 LQYKAFSKIIKEYEDTKYKEWVQDASLFCDNMMKKNILKVVFKKEDDP----VPQKARGM 287
QY S ++ E+E + W+++ S + + +F + + V + +
Sbjct: 757 RQYNKISYVLVEFEVVYHTAWIREIS-----QLHYALQATLFVRHPETGKLLVNFDPKIL 811
Query: 288 QLTAAGRAHVAKK-KASNTSLKPLDIVNKEIADKRRRDKAL-----MLMRIPGQHYENVR 341
++ + + K + + L + +K ADK L + +P + N+
Sbjct: 812 EVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPSV-FVNLM 870
Query: 342 SP--SSVSLLAKEGLTDVTWRDLTVHKLIQEYNL 373
+P V + ++GLT +TW LT+ QE L
Sbjct: 871 TPKMKKVESVLRQGLTVLTWSSLTLESFFQEVEL 904
Score = 42.7 bits (96), Expect = 0.027
Identities = 22/98 (22%), Positives = 48/98 (48%)
Query: 378 NFDKDLFLVIHEAELMEQLGFDVPSNVRDVAMQKSRLFYELEALSKIIAKYNKNASSLSP 437
NFD + V+ E + M ++ DVP + + +S+L + L ++ Y++ +
Sbjct: 805 NFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPS 864
Query: 438 SETYLMKRHLLDMERHILPGLTRITWTALGINDYIKDI 475
LM + +E + GLT +TW++L + + +++
Sbjct: 865 VFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQEV 902
>AL035555-1|CAI19819.1| 4490|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4490
Score = 849 bits (2100), Expect = 0.0
Identities = 540/1666 (32%), Positives = 877/1666 (52%), Gaps = 82/1666 (4%)
Query: 782 IKGLEDFKLVMATITQVQQMTITAEVKYRGMQEIFHMLKQHGINVTDEDLQFAKSLEASW 841
I+ L+D + M ++ ++ I ++ ++E + +L + + VT E+ + +L S+
Sbjct: 1113 IRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYSF 1172
Query: 842 GSLYQTSLFRGNTLEQTKEKFSKLNVVE-ISNFLKELDDFVEKFDNEGPATVEDDMDRGL 900
L ++ L Q + KF K N++E + F +++ +F E ++ EGP
Sbjct: 1173 NKLQSKAVSVQEDLVQVQPKF-KSNLLESVEVFREDVINFAEAYELEGPMVPNIPPQEAS 1231
Query: 901 LLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNFNRTKADYSAMDQIYKIYKAQKNA 960
++ + D+L + + EQLF P+ D+ ++T+ + + + ++Y +Y ++
Sbjct: 1232 NRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSS 1291
Query: 961 REVWAKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLMLDLKMKQFKGVVPLMVS 1020
+ + LW +++ + + + +F RKLPK ++ L L ++ F PL+
Sbjct: 1292 ISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEM 1351
Query: 1021 LKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMELHKYQDVAEEIVNHAIKELAIE 1080
+ N+AM++RHW + TG FD+ D F L N+ L K++D E+I AIKE IE
Sbjct: 1352 MTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIE 1411
Query: 1081 RGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVVKLDDDSMSLQSMAASQFIGPF 1140
+ V E W N + S + +GE +I+ ++D M L S+ ++++ PF
Sbjct: 1412 AKLTQVIENWTNQNLSFAAFKGKGELL-LKGTESGEIITLMEDSLMVLGSLLSNRYNAPF 1470
Query: 1141 LTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGGDIRTQLPEEAKKFDDIDRAFRK 1200
+Q W ++LS S+IIEEW+ Q W+YLE +FVGGDI QLP+EAK+F +ID+++ K
Sbjct: 1471 KKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIK 1530
Query: 1201 IMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASSDVTRKQINLSQAIAWADR 1260
IM + NV++CC +G + L Q +S + + +K++ + +D
Sbjct: 1531 IMQRAHENPNVINCC-VGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDP 1589
Query: 1261 ASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYVDHTNRPVAAKMISAEGEIMDF 1320
L ++ ++ Q S DNI + + +R +A +IS EGE +
Sbjct: 1590 VLLEILGQASDSHTIQPHLPAVS------DNINEVTFHAKDYDRIMA--VISREGEKIVL 1641
Query: 1321 RNVVYTEGRVEDWMNLVLVEMRHTNKFITKKAIFYYGKNWKVPRTDWILEYQGMVCLAAN 1380
N V +G VE W+ L L++M+ ++ ++ FY + ++ + V L
Sbjct: 1642 DNSVMAKGPVEIWL-LDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGLLGI 1700
Query: 1381 GVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQLDGLVVKVRQDLSSNDRLKFRTITTID 1440
+ WT ++EE LR K +++ M+ Q+ + L+ L+ + DLS DR+KF T+ TI
Sbjct: 1701 QMLWTHDSEEA-LRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIH 1759
Query: 1441 VHARDIIEGFVRDNITEAAEFEWESQLRFYWLKKDDNLWIRQCTGV-FEYGYEYMGLNGR 1499
VH RDI + V+ +I +FEW Q RFY+ K+D + + T V F Y E++G R
Sbjct: 1760 VHQRDIFDDLVKMHIKSPTDFEWLKQSRFYF-KEDLDQTVVSITDVDFIYQNEFLGCTDR 1818
Query: 1500 LVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDF 1559
LVITPLTDR Y+T+ QAL M + D+ + LG VV NC + MDF
Sbjct: 1819 LVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDF 1878
Query: 1560 RAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLKRFTVNTDVLKP 1619
R +G+I GL Q G+WGCFDEFNRI++ VLSV + Q+ + +A + K+F +
Sbjct: 1879 RGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD----- 1933
Query: 1620 SQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTELPESVKALFRPVVCILPDLEMI 1679
G + ++ + GIF+TMNPGYAGR ELPE++K FR V ++PD ++I
Sbjct: 1934 -------------GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQII 1980
Query: 1680 CQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTAVLRMAGKLRRDSPG 1739
++ L S GFL +LA+K VLYK+ EQL+KQ HYD+GLR + +VLR G +R P
Sbjct: 1981 MRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPE 2040
Query: 1740 LSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEKDG 1799
SE+ ++MR LRDMN K V ED PLFL LI DLFPGL+ Y E AV ++ +G
Sbjct: 2041 DSELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEG 2100
Query: 1800 YVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNLGLPTKLTVVNPK 1859
+ P K+VQLYET + RH M +GP+G GKT ++ L+KAQT G P + +NPK
Sbjct: 2101 LINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQTECGRPHREMRMNPK 2160
Query: 1860 ACSVIELYGILDPVTRDWTDGLYSKIFREMNRPAEKNERRYSLFDGDVDALWIENMNSVM 1919
A + +++G LD T DWTDG++S ++R+ + A+K E + + DG VDA+WIEN+NSV+
Sbjct: 2161 AITAPQMFGRLDTATNDWTDGIFSTLWRKTLK-AKKGENIFLILDGPVDAIWIENLNSVL 2219
Query: 1920 DDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGYEPYWERWL 1979
DDNK LTLANG+RI +AP C LLFEV ++ ASPATVSR GMV++ L + P + WL
Sbjct: 2220 DDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWL 2279
Query: 1980 STRSNEEEREQLSGLFEHYVPGAINYIVFGMFGLQQQTPLKTIVPQTPLNLVMQLCYMIS 2039
R+ +E L+ L+E Y+ + P ++ N ++Q ++
Sbjct: 2280 KKRTAQEAAVFLT-LYEKVFEDTYTYMKLNL------NPKMQLL---ECNYIVQSLNLLE 2329
Query: 2040 GLLPNNEDTNMEIDKTVVECVFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVEDNPE 2099
GL+P+ E+ + + + + +F+ + SLGA + R + ++++ E
Sbjct: 2330 GLIPSKEEGGVSCVEHLHK-LFVFGLMWSLGALLELESREKLEAFLRQ----------HE 2378
Query: 2100 KKATTKHFPMGF-PTLYDYCLELTTKLWEAWDWLVPEYEHDRDM--KFPAILVPTVDTLR 2156
K P G T+Y++ + WE W+ + Y + D ++ +ILVP VD +R
Sbjct: 2379 SKLDLPEIPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIR 2437
Query: 2157 LTWLIKIMESIIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMP 2216
+LI ++I +Q T Q ++V+ K + P V + P
Sbjct: 2438 TNFLI---DTIAKQHKAVLLTGE---QGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEP 2491
Query: 2217 ------IVSHNNQCVPSLCST---RVQTL----LSHPLVDTYGTQQPIALLKLLFERKGF 2263
I S+ ++ + S R T+ ++ P+++ +G Q +++ + E +G
Sbjct: 2492 MMFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGM 2551
Query: 2264 YDRGKDLNWKNLKDIGFLAAMGKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSIL 2323
Y K ++ + D+ +AAM GGGRND+ R F+V+N PS ++ I+ I
Sbjct: 2552 YSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIG 2611
Query: 2324 KGHFE---IFPEEIQGIVEKIVQMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMC 2380
G+F+ F +I ++ +V + L++ V++ PTP+KFHYIFNLRDLSRI GM
Sbjct: 2612 CGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGML 2671
Query: 2381 LTHANYFSEKRTVVRCWRNEFTRVICDRLINQQDNELMRGHIQEHV 2426
A + T++ +++E +RVI DR I +D + H+ V
Sbjct: 2672 TIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAV 2717
Score = 652 bits (1612), Expect = 0.0
Identities = 366/1107 (33%), Positives = 591/1107 (53%), Gaps = 26/1107 (2%)
Query: 2682 AKCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKI-PEEFRPIIVEHVVHVHMSV 2740
A+ FPGL++ T+DW WP++AL+AVA+ FL+D + E + +VE + H V
Sbjct: 2961 ARSLKFPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMV 3020
Query: 2741 ARYSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQ 2800
+ + R RR +VTPK Y+ F+ Y + EK FI Q ER+ GL K+ EA+
Sbjct: 3021 SESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASES 3080
Query: 2801 LEDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVE 2860
+ L+ LAV++ +A + + + +L E++ + + + + I E
Sbjct: 3081 VAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSE 3140
Query: 2861 KXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVII--RGIKD 2918
K NDI +R A PP + + +CV+++ + I
Sbjct: 3141 KVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDP 3200
Query: 2919 V-----------SWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLDTM 2966
V SW + +M+ FL +LQ+ D I + V+ ++ + ++
Sbjct: 3201 VTMDPEKSCCKPSWGESLKLMSATGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESA 3260
Query: 2967 QQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQK 3026
+++ GLL + A+ + + A L +D Q
Sbjct: 3261 KKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQA 3320
Query: 3027 TLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSR 3086
LD + +++ AM + +L + D +++ AA L+ GLS E+ RWT+ + +R
Sbjct: 3321 ELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINR 3380
Query: 3087 LIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSG 3146
L+G+ LL T FLSY GPF+ FR ++ + W ++ R IP T + L + +
Sbjct: 3381 LVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARKIPFTENLNLISMLVDPPTIGE 3440
Query: 3147 WNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLR 3206
W +GLP D+LS+QNGI+ T+A+R+PL IDPQTQ TWIK KE +N+L+V S N F
Sbjct: 3441 WGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRT 3500
Query: 3207 QLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTF-VMLGSTEVDYDPNFRMYL 3265
LE ++ G P+L +D++E +DP +DNVLEKN ++SG TF V +G E D F++Y+
Sbjct: 3501 HLEDSLSLGRPLLIEDIHEELDPALDNVLEKNF-IKSGTTFKVKVGDKECDIMDTFKLYI 3559
Query: 3266 TTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANK 3325
TTKL NP F P AK VI++TVT++GLE+QLL V+ E+ +LE +R L+ + + NK
Sbjct: 3560 TTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNK 3619
Query: 3326 SLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRD 3385
+ LED+LL +L+ + G+++D+ L+ L TK AAEV EKL +A T I ++
Sbjct: 3620 RKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQE 3679
Query: 3386 GYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDM 3445
+RP A RGSIL+F++++M+ VN MYQ SL+ +L +F S+ ++ + + KR+ NII+
Sbjct: 3680 EFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEY 3739
Query: 3446 LTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLE-KSARSSP 3504
LT V+ Y G++E HK LF M +K++ V + IKG +L+ K+ P
Sbjct: 3740 LTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKP 3799
Query: 3505 APWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLK 3564
W+ W ++++LS P FA + + I++ + W+ WFD D PE IP+ Y + L
Sbjct: 3800 YRWILDMTWLNLVELSK-LPQ-FAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLD 3857
Query: 3565 PFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPG 3624
L+L+R + DR YI ++ E+Y P +++L+ E++ TP++ LS G
Sbjct: 3858 TCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMG 3917
Query: 3625 SDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFL 3684
SDPT + LA + + + +S+GQGQE A L++ ++ G W++LQNCHL + F+
Sbjct: 3918 SDPTNQIDALAKKLKL---ECRTISMGQGQEVHARKLIQMSMQQGGWVLLQNCHLGLEFM 3974
Query: 3685 RELEKQLELMTKPHPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLNLRNTYFKMR 3741
EL + L +R+W+TT+P FPI +LQ SLK EPP G++ L+ T+ +
Sbjct: 3975 EELLETLITTEASDDSFRVWITTEPHDRFPITLLQTSLKFTNEPPQGVRAGLKRTFAGIN 4034
Query: 3742 ARALEECPHPQFKKLVYVLAFFHAVVQ 3768
L+ P +K ++Y +AF H+ VQ
Sbjct: 4035 QDLLDISNLPMWKPMLYTVAFLHSTVQ 4061
Score = 192 bits (469), Expect = 2e-47
Identities = 128/408 (31%), Positives = 201/408 (49%), Gaps = 17/408 (4%)
Query: 3745 LEECPHPQFKKLVYVLAFFHAVVQVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFH 3804
L+EC KK V + + +V YGG + + E +F+ F
Sbjct: 4093 LDEC---DIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMFEP--SFC 4147
Query: 3805 FYKDYAFDYVIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIE 3864
FY Y IP D+Y ++I +LP + PEVFGLHPNA+I Y S + +
Sbjct: 4148 FYTGYK----IPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQSNTASAVLETITN 4203
Query: 3865 LQPQTSEAGGAMSREDFIDNIAVDVLSKLPTLYEIWRVRKQ-FEM-NITPTLVVLLQELE 3922
+QP+ S G +RE + ++ D+LSKLP Y V+ + +M ++ + L QE++
Sbjct: 4204 IQPKESGGGVGETREAIVYRLSEDMLSKLPPDYIPHEVKSRLIKMGHLNSMNIFLRQEID 4263
Query: 3923 RFNRLISRMGSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGW 3982
R R+IS + S+LS L+ A+ G I M L + ++++ ++PQ+W+ ++ LG W
Sbjct: 4264 RMQRVISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQLWKRVS-WDSSTLGFW 4322
Query: 3983 MDHFIARTKQYTDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYT-WPLDRSTQFTKV 4041
+ R Q++ W P V W++G P+ +L A Q R + W LD T +V
Sbjct: 4323 FTELLERNAQFSTWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDTVTIHNEV 4382
Query: 4042 TSWVSADEIEERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHK 4101
+ +EI P G Y+ GLY++GA WD G L S PKVL T+LP+++I I
Sbjct: 4383 LR-QTKEEITSPPGEGVYIYGLYMDGAAWDRRNGKLMESTPKVLFTQLPVLHIFAINSTA 4441
Query: 4102 LKLQNTLRTPVYTTSQRRNAMGVGLVFESDLWTTEHCSHWILQGVCLI 4149
K P+Y +R + + +V+ L T HWIL+GV L+
Sbjct: 4442 PKDPKLYVCPIYKKPRRTDLTFITVVY---LRTVLSPDHWILRGVALL 4486
Score = 109 bits (262), Expect = 2e-22
Identities = 55/154 (35%), Positives = 85/154 (55%), Gaps = 2/154 (1%)
Query: 2515 RYYEDLLDYEAIYFLFQEILDEYNE--RNAKMSIVLFEDCLEHLTRTHRILRMDRGNAMX 2572
+ YE + ++ + Q ++NE R + +V F+D + HL + RI+R GNA+
Sbjct: 2759 KIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALL 2818
Query: 2573 XXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMYLQLGVDNKKTVFLFT 2632
+LA+F AG ++F+IT+TR+YN DD+K +Y G D K F+FT
Sbjct: 2819 VGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITFIFT 2878
Query: 2633 AAQILEEGFLEFINNILMIGMIPALFGDDEKDSI 2666
++I +E FLE++NN+L G I LF DE D I
Sbjct: 2879 DSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEI 2912
Score = 96.7 bits (230), Expect = 2e-18
Identities = 74/334 (22%), Positives = 156/334 (46%), Gaps = 22/334 (6%)
Query: 54 ERIFGLELKSIISDPT--QIDDVRKRVKNLVYPIRTVDFSVFVFDNKENWDVIMGDFWNE 111
E I ++ S +S+ T ID + + +N+ ++ + + + + +D DF +
Sbjct: 374 EMITVVQTYSTLSNSTIEGIDIMAIKFRNIYQGVKKKQYDI-LDPRRTEFDTDFLDFMTK 432
Query: 112 VRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEI 171
+ LE + + ++N SFG + SS++AL +L +F + + + +++ + +++ ++ E+
Sbjct: 433 INGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLNI-PCLGLEINHTIERILQYYVAEL 491
Query: 172 TAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMKQPIMKFQKVSELNECEQKKEAF 231
A + + + +PPL RN PP+AG I W R L+ ++ +PI F K S++ K
Sbjct: 492 DATKKLYHSQKDDPPLARNMPPIAGKILWVRQLYRRISEPINYFFKNSDILSSPDGKAVI 551
Query: 232 LQYKAFSKIIKEYEDTKYKEWVQDASLFCDNMMKKNILKVVFKKEDDP----VPQKARGM 287
QY S ++ E+E + W+++ S + + +F + + V + +
Sbjct: 552 RQYNKISYVLVEFEVVYHTAWIREIS-----QLHYALQATLFVRHPETGKLLVNFDPKIL 606
Query: 288 QLTAAGRAHVAKK-KASNTSLKPLDIVNKEIADKRRRDKAL-----MLMRIPGQHYENVR 341
++ + + K + + L + +K ADK L + +P + N+
Sbjct: 607 EVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPSV-FVNLM 665
Query: 342 SP--SSVSLLAKEGLTDVTWRDLTVHKLIQEYNL 373
+P V + ++GLT +TW LT+ QE L
Sbjct: 666 TPKMKKVESVLRQGLTVLTWSSLTLESFFQEVEL 699
Score = 42.7 bits (96), Expect = 0.027
Identities = 22/98 (22%), Positives = 48/98 (48%)
Query: 378 NFDKDLFLVIHEAELMEQLGFDVPSNVRDVAMQKSRLFYELEALSKIIAKYNKNASSLSP 437
NFD + V+ E + M ++ DVP + + +S+L + L ++ Y++ +
Sbjct: 600 NFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPS 659
Query: 438 SETYLMKRHLLDMERHILPGLTRITWTALGINDYIKDI 475
LM + +E + GLT +TW++L + + +++
Sbjct: 660 VFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQEV 697
>AL034345-4|CAI42436.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 849 bits (2100), Expect = 0.0
Identities = 540/1666 (32%), Positives = 877/1666 (52%), Gaps = 82/1666 (4%)
Query: 782 IKGLEDFKLVMATITQVQQMTITAEVKYRGMQEIFHMLKQHGINVTDEDLQFAKSLEASW 841
I+ L+D + M ++ ++ I ++ ++E + +L + + VT E+ + +L S+
Sbjct: 1318 IRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYSF 1377
Query: 842 GSLYQTSLFRGNTLEQTKEKFSKLNVVE-ISNFLKELDDFVEKFDNEGPATVEDDMDRGL 900
L ++ L Q + KF K N++E + F +++ +F E ++ EGP
Sbjct: 1378 NKLQSKAVSVQEDLVQVQPKF-KSNLLESVEVFREDVINFAEAYELEGPMVPNIPPQEAS 1436
Query: 901 LLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNFNRTKADYSAMDQIYKIYKAQKNA 960
++ + D+L + + EQLF P+ D+ ++T+ + + + ++Y +Y ++
Sbjct: 1437 NRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSS 1496
Query: 961 REVWAKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLMLDLKMKQFKGVVPLMVS 1020
+ + LW +++ + + + +F RKLPK ++ L L ++ F PL+
Sbjct: 1497 ISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEM 1556
Query: 1021 LKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMELHKYQDVAEEIVNHAIKELAIE 1080
+ N+AM++RHW + TG FD+ D F L N+ L K++D E+I AIKE IE
Sbjct: 1557 MTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIE 1616
Query: 1081 RGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVVKLDDDSMSLQSMAASQFIGPF 1140
+ V E W N + S + +GE +I+ ++D M L S+ ++++ PF
Sbjct: 1617 AKLTQVIENWTNQNLSFAAFKGKGELL-LKGTESGEIITLMEDSLMVLGSLLSNRYNAPF 1675
Query: 1141 LTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGGDIRTQLPEEAKKFDDIDRAFRK 1200
+Q W ++LS S+IIEEW+ Q W+YLE +FVGGDI QLP+EAK+F +ID+++ K
Sbjct: 1676 KKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIK 1735
Query: 1201 IMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASSDVTRKQINLSQAIAWADR 1260
IM + NV++CC +G + L Q +S + + +K++ + +D
Sbjct: 1736 IMQRAHENPNVINCC-VGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDP 1794
Query: 1261 ASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYVDHTNRPVAAKMISAEGEIMDF 1320
L ++ ++ Q S DNI + + +R +A +IS EGE +
Sbjct: 1795 VLLEILGQASDSHTIQPHLPAVS------DNINEVTFHAKDYDRIMA--VISREGEKIVL 1846
Query: 1321 RNVVYTEGRVEDWMNLVLVEMRHTNKFITKKAIFYYGKNWKVPRTDWILEYQGMVCLAAN 1380
N V +G VE W+ L L++M+ ++ ++ FY + ++ + V L
Sbjct: 1847 DNSVMAKGPVEIWL-LDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGLLGI 1905
Query: 1381 GVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQLDGLVVKVRQDLSSNDRLKFRTITTID 1440
+ WT ++EE LR K +++ M+ Q+ + L+ L+ + DLS DR+KF T+ TI
Sbjct: 1906 QMLWTHDSEEA-LRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIH 1964
Query: 1441 VHARDIIEGFVRDNITEAAEFEWESQLRFYWLKKDDNLWIRQCTGV-FEYGYEYMGLNGR 1499
VH RDI + V+ +I +FEW Q RFY+ K+D + + T V F Y E++G R
Sbjct: 1965 VHQRDIFDDLVKMHIKSPTDFEWLKQSRFYF-KEDLDQTVVSITDVDFIYQNEFLGCTDR 2023
Query: 1500 LVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDF 1559
LVITPLTDR Y+T+ QAL M + D+ + LG VV NC + MDF
Sbjct: 2024 LVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDF 2083
Query: 1560 RAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLKRFTVNTDVLKP 1619
R +G+I GL Q G+WGCFDEFNRI++ VLSV + Q+ + +A + K+F +
Sbjct: 2084 RGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD----- 2138
Query: 1620 SQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTELPESVKALFRPVVCILPDLEMI 1679
G + ++ + GIF+TMNPGYAGR ELPE++K FR V ++PD ++I
Sbjct: 2139 -------------GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQII 2185
Query: 1680 CQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTAVLRMAGKLRRDSPG 1739
++ L S GFL +LA+K VLYK+ EQL+KQ HYD+GLR + +VLR G +R P
Sbjct: 2186 MRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPE 2245
Query: 1740 LSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEKDG 1799
SE+ ++MR LRDMN K V ED PLFL LI DLFPGL+ Y E AV ++ +G
Sbjct: 2246 DSELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEG 2305
Query: 1800 YVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNLGLPTKLTVVNPK 1859
+ P K+VQLYET + RH M +GP+G GKT ++ L+KAQT G P + +NPK
Sbjct: 2306 LINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQTECGRPHREMRMNPK 2365
Query: 1860 ACSVIELYGILDPVTRDWTDGLYSKIFREMNRPAEKNERRYSLFDGDVDALWIENMNSVM 1919
A + +++G LD T DWTDG++S ++R+ + A+K E + + DG VDA+WIEN+NSV+
Sbjct: 2366 AITAPQMFGRLDTATNDWTDGIFSTLWRKTLK-AKKGENIFLILDGPVDAIWIENLNSVL 2424
Query: 1920 DDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGYEPYWERWL 1979
DDNK LTLANG+RI +AP C LLFEV ++ ASPATVSR GMV++ L + P + WL
Sbjct: 2425 DDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWL 2484
Query: 1980 STRSNEEEREQLSGLFEHYVPGAINYIVFGMFGLQQQTPLKTIVPQTPLNLVMQLCYMIS 2039
R+ +E L+ L+E Y+ + P ++ N ++Q ++
Sbjct: 2485 KKRTAQEAAVFLT-LYEKVFEDTYTYMKLNL------NPKMQLL---ECNYIVQSLNLLE 2534
Query: 2040 GLLPNNEDTNMEIDKTVVECVFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVEDNPE 2099
GL+P+ E+ + + + + +F+ + SLGA + R + ++++ E
Sbjct: 2535 GLIPSKEEGGVSCVEHLHK-LFVFGLMWSLGALLELESREKLEAFLRQ----------HE 2583
Query: 2100 KKATTKHFPMGF-PTLYDYCLELTTKLWEAWDWLVPEYEHDRDM--KFPAILVPTVDTLR 2156
K P G T+Y++ + WE W+ + Y + D ++ +ILVP VD +R
Sbjct: 2584 SKLDLPEIPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIR 2642
Query: 2157 LTWLIKIMESIIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMP 2216
+LI ++I +Q T Q ++V+ K + P V + P
Sbjct: 2643 TNFLI---DTIAKQHKAVLLTGE---QGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEP 2696
Query: 2217 ------IVSHNNQCVPSLCST---RVQTL----LSHPLVDTYGTQQPIALLKLLFERKGF 2263
I S+ ++ + S R T+ ++ P+++ +G Q +++ + E +G
Sbjct: 2697 MMFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGM 2756
Query: 2264 YDRGKDLNWKNLKDIGFLAAMGKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSIL 2323
Y K ++ + D+ +AAM GGGRND+ R F+V+N PS ++ I+ I
Sbjct: 2757 YSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIG 2816
Query: 2324 KGHFE---IFPEEIQGIVEKIVQMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMC 2380
G+F+ F +I ++ +V + L++ V++ PTP+KFHYIFNLRDLSRI GM
Sbjct: 2817 CGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGML 2876
Query: 2381 LTHANYFSEKRTVVRCWRNEFTRVICDRLINQQDNELMRGHIQEHV 2426
A + T++ +++E +RVI DR I +D + H+ V
Sbjct: 2877 TIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAV 2922
Score = 652 bits (1612), Expect = 0.0
Identities = 366/1107 (33%), Positives = 591/1107 (53%), Gaps = 26/1107 (2%)
Query: 2682 AKCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKI-PEEFRPIIVEHVVHVHMSV 2740
A+ FPGL++ T+DW WP++AL+AVA+ FL+D + E + +VE + H V
Sbjct: 3166 ARSLKFPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMV 3225
Query: 2741 ARYSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQ 2800
+ + R RR +VTPK Y+ F+ Y + EK FI Q ER+ GL K+ EA+
Sbjct: 3226 SESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASES 3285
Query: 2801 LEDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVE 2860
+ L+ LAV++ +A + + + +L E++ + + + + I E
Sbjct: 3286 VAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSE 3345
Query: 2861 KXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVII--RGIKD 2918
K NDI +R A PP + + +CV+++ + I
Sbjct: 3346 KVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDP 3405
Query: 2919 V-----------SWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLDTM 2966
V SW + +M+ FL +LQ+ D I + V+ ++ + ++
Sbjct: 3406 VTMDPEKSCCKPSWGESLKLMSATGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESA 3465
Query: 2967 QQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQK 3026
+++ GLL + A+ + + A L +D Q
Sbjct: 3466 KKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQA 3525
Query: 3027 TLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSR 3086
LD + +++ AM + +L + D +++ AA L+ GLS E+ RWT+ + +R
Sbjct: 3526 ELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINR 3585
Query: 3087 LIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSG 3146
L+G+ LL T FLSY GPF+ FR ++ + W ++ R IP T + L + +
Sbjct: 3586 LVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARKIPFTENLNLISMLVDPPTIGE 3645
Query: 3147 WNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLR 3206
W +GLP D+LS+QNGI+ T+A+R+PL IDPQTQ TWIK KE +N+L+V S N F
Sbjct: 3646 WGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRT 3705
Query: 3207 QLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTF-VMLGSTEVDYDPNFRMYL 3265
LE ++ G P+L +D++E +DP +DNVLEKN ++SG TF V +G E D F++Y+
Sbjct: 3706 HLEDSLSLGRPLLIEDIHEELDPALDNVLEKNF-IKSGTTFKVKVGDKECDIMDTFKLYI 3764
Query: 3266 TTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANK 3325
TTKL NP F P AK VI++TVT++GLE+QLL V+ E+ +LE +R L+ + + NK
Sbjct: 3765 TTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNK 3824
Query: 3326 SLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRD 3385
+ LED+LL +L+ + G+++D+ L+ L TK AAEV EKL +A T I ++
Sbjct: 3825 RKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQE 3884
Query: 3386 GYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDM 3445
+RP A RGSIL+F++++M+ VN MYQ SL+ +L +F S+ ++ + + KR+ NII+
Sbjct: 3885 EFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEY 3944
Query: 3446 LTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLE-KSARSSP 3504
LT V+ Y G++E HK LF M +K++ V + IKG +L+ K+ P
Sbjct: 3945 LTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKP 4004
Query: 3505 APWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLK 3564
W+ W ++++LS P FA + + I++ + W+ WFD D PE IP+ Y + L
Sbjct: 4005 YRWILDMTWLNLVELSK-LPQ-FAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLD 4062
Query: 3565 PFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPG 3624
L+L+R + DR YI ++ E+Y P +++L+ E++ TP++ LS G
Sbjct: 4063 TCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMG 4122
Query: 3625 SDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFL 3684
SDPT + LA + + + +S+GQGQE A L++ ++ G W++LQNCHL + F+
Sbjct: 4123 SDPTNQIDALAKKLKL---ECRTISMGQGQEVHARKLIQMSMQQGGWVLLQNCHLGLEFM 4179
Query: 3685 RELEKQLELMTKPHPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLNLRNTYFKMR 3741
EL + L +R+W+TT+P FPI +LQ SLK EPP G++ L+ T+ +
Sbjct: 4180 EELLETLITTEASDDSFRVWITTEPHDRFPITLLQTSLKFTNEPPQGVRAGLKRTFAGIN 4239
Query: 3742 ARALEECPHPQFKKLVYVLAFFHAVVQ 3768
L+ P +K ++Y +AF H+ VQ
Sbjct: 4240 QDLLDISNLPMWKPMLYTVAFLHSTVQ 4266
Score = 192 bits (469), Expect = 2e-47
Identities = 128/408 (31%), Positives = 201/408 (49%), Gaps = 17/408 (4%)
Query: 3745 LEECPHPQFKKLVYVLAFFHAVVQVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFH 3804
L+EC KK V + + +V YGG + + E +F+ F
Sbjct: 4298 LDEC---DIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMFEP--SFC 4352
Query: 3805 FYKDYAFDYVIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIE 3864
FY Y IP D+Y ++I +LP + PEVFGLHPNA+I Y S + +
Sbjct: 4353 FYTGYK----IPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQSNTASAVLETITN 4408
Query: 3865 LQPQTSEAGGAMSREDFIDNIAVDVLSKLPTLYEIWRVRKQ-FEM-NITPTLVVLLQELE 3922
+QP+ S G +RE + ++ D+LSKLP Y V+ + +M ++ + L QE++
Sbjct: 4409 IQPKESGGGVGETREAIVYRLSEDMLSKLPPDYIPHEVKSRLIKMGHLNSMNIFLRQEID 4468
Query: 3923 RFNRLISRMGSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGW 3982
R R+IS + S+LS L+ A+ G I M L + ++++ ++PQ+W+ ++ LG W
Sbjct: 4469 RMQRVISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQLWKRVS-WDSSTLGFW 4527
Query: 3983 MDHFIARTKQYTDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYT-WPLDRSTQFTKV 4041
+ R Q++ W P V W++G P+ +L A Q R + W LD T +V
Sbjct: 4528 FTELLERNAQFSTWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDTVTIHNEV 4587
Query: 4042 TSWVSADEIEERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHK 4101
+ +EI P G Y+ GLY++GA WD G L S PKVL T+LP+++I I
Sbjct: 4588 LR-QTKEEITSPPGEGVYIYGLYMDGAAWDRRNGKLMESTPKVLFTQLPVLHIFAINSTA 4646
Query: 4102 LKLQNTLRTPVYTTSQRRNAMGVGLVFESDLWTTEHCSHWILQGVCLI 4149
K P+Y +R + + +V+ L T HWIL+GV L+
Sbjct: 4647 PKDPKLYVCPIYKKPRRTDLTFITVVY---LRTVLSPDHWILRGVALL 4691
Score = 109 bits (262), Expect = 2e-22
Identities = 55/154 (35%), Positives = 85/154 (55%), Gaps = 2/154 (1%)
Query: 2515 RYYEDLLDYEAIYFLFQEILDEYNE--RNAKMSIVLFEDCLEHLTRTHRILRMDRGNAMX 2572
+ YE + ++ + Q ++NE R + +V F+D + HL + RI+R GNA+
Sbjct: 2964 KIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALL 3023
Query: 2573 XXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMYLQLGVDNKKTVFLFT 2632
+LA+F AG ++F+IT+TR+YN DD+K +Y G D K F+FT
Sbjct: 3024 VGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITFIFT 3083
Query: 2633 AAQILEEGFLEFINNILMIGMIPALFGDDEKDSI 2666
++I +E FLE++NN+L G I LF DE D I
Sbjct: 3084 DSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEI 3117
Score = 96.7 bits (230), Expect = 2e-18
Identities = 74/334 (22%), Positives = 156/334 (46%), Gaps = 22/334 (6%)
Query: 54 ERIFGLELKSIISDPT--QIDDVRKRVKNLVYPIRTVDFSVFVFDNKENWDVIMGDFWNE 111
E I ++ S +S+ T ID + + +N+ ++ + + + + +D DF +
Sbjct: 579 EMITVVQTYSTLSNSTIEGIDIMAIKFRNIYQGVKKKQYDI-LDPRRTEFDTDFLDFMTK 637
Query: 112 VRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEI 171
+ LE + + ++N SFG + SS++AL +L +F + + + +++ + +++ ++ E+
Sbjct: 638 INGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLNI-PCLGLEINHTIERILQYYVAEL 696
Query: 172 TAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMKQPIMKFQKVSELNECEQKKEAF 231
A + + + +PPL RN PP+AG I W R L+ ++ +PI F K S++ K
Sbjct: 697 DATKKLYHSQKDDPPLARNMPPIAGKILWVRQLYRRISEPINYFFKNSDILSSPDGKAVI 756
Query: 232 LQYKAFSKIIKEYEDTKYKEWVQDASLFCDNMMKKNILKVVFKKEDDP----VPQKARGM 287
QY S ++ E+E + W+++ S + + +F + + V + +
Sbjct: 757 RQYNKISYVLVEFEVVYHTAWIREIS-----QLHYALQATLFVRHPETGKLLVNFDPKIL 811
Query: 288 QLTAAGRAHVAKK-KASNTSLKPLDIVNKEIADKRRRDKAL-----MLMRIPGQHYENVR 341
++ + + K + + L + +K ADK L + +P + N+
Sbjct: 812 EVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPSV-FVNLM 870
Query: 342 SP--SSVSLLAKEGLTDVTWRDLTVHKLIQEYNL 373
+P V + ++GLT +TW LT+ QE L
Sbjct: 871 TPKMKKVESVLRQGLTVLTWSSLTLESFFQEVEL 904
Score = 42.7 bits (96), Expect = 0.027
Identities = 22/98 (22%), Positives = 48/98 (48%)
Query: 378 NFDKDLFLVIHEAELMEQLGFDVPSNVRDVAMQKSRLFYELEALSKIIAKYNKNASSLSP 437
NFD + V+ E + M ++ DVP + + +S+L + L ++ Y++ +
Sbjct: 805 NFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPS 864
Query: 438 SETYLMKRHLLDMERHILPGLTRITWTALGINDYIKDI 475
LM + +E + GLT +TW++L + + +++
Sbjct: 865 VFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQEV 902
>AL034345-3|CAI42435.1| 4176|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4176
Score = 849 bits (2100), Expect = 0.0
Identities = 540/1666 (32%), Positives = 877/1666 (52%), Gaps = 82/1666 (4%)
Query: 782 IKGLEDFKLVMATITQVQQMTITAEVKYRGMQEIFHMLKQHGINVTDEDLQFAKSLEASW 841
I+ L+D + M ++ ++ I ++ ++E + +L + + VT E+ + +L S+
Sbjct: 1318 IRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYSF 1377
Query: 842 GSLYQTSLFRGNTLEQTKEKFSKLNVVE-ISNFLKELDDFVEKFDNEGPATVEDDMDRGL 900
L ++ L Q + KF K N++E + F +++ +F E ++ EGP
Sbjct: 1378 NKLQSKAVSVQEDLVQVQPKF-KSNLLESVEVFREDVINFAEAYELEGPMVPNIPPQEAS 1436
Query: 901 LLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNFNRTKADYSAMDQIYKIYKAQKNA 960
++ + D+L + + EQLF P+ D+ ++T+ + + + ++Y +Y ++
Sbjct: 1437 NRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSS 1496
Query: 961 REVWAKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLMLDLKMKQFKGVVPLMVS 1020
+ + LW +++ + + + +F RKLPK ++ L L ++ F PL+
Sbjct: 1497 ISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEM 1556
Query: 1021 LKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMELHKYQDVAEEIVNHAIKELAIE 1080
+ N+AM++RHW + TG FD+ D F L N+ L K++D E+I AIKE IE
Sbjct: 1557 MTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIE 1616
Query: 1081 RGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVVKLDDDSMSLQSMAASQFIGPF 1140
+ V E W N + S + +GE +I+ ++D M L S+ ++++ PF
Sbjct: 1617 AKLTQVIENWTNQNLSFAAFKGKGELL-LKGTESGEIITLMEDSLMVLGSLLSNRYNAPF 1675
Query: 1141 LTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGGDIRTQLPEEAKKFDDIDRAFRK 1200
+Q W ++LS S+IIEEW+ Q W+YLE +FVGGDI QLP+EAK+F +ID+++ K
Sbjct: 1676 KKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIK 1735
Query: 1201 IMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASSDVTRKQINLSQAIAWADR 1260
IM + NV++CC +G + L Q +S + + +K++ + +D
Sbjct: 1736 IMQRAHENPNVINCC-VGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDP 1794
Query: 1261 ASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYVDHTNRPVAAKMISAEGEIMDF 1320
L ++ ++ Q S DNI + + +R +A +IS EGE +
Sbjct: 1795 VLLEILGQASDSHTIQPHLPAVS------DNINEVTFHAKDYDRIMA--VISREGEKIVL 1846
Query: 1321 RNVVYTEGRVEDWMNLVLVEMRHTNKFITKKAIFYYGKNWKVPRTDWILEYQGMVCLAAN 1380
N V +G VE W+ L L++M+ ++ ++ FY + ++ + V L
Sbjct: 1847 DNSVMAKGPVEIWL-LDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGLLGI 1905
Query: 1381 GVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQLDGLVVKVRQDLSSNDRLKFRTITTID 1440
+ WT ++EE LR K +++ M+ Q+ + L+ L+ + DLS DR+KF T+ TI
Sbjct: 1906 QMLWTHDSEEA-LRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIH 1964
Query: 1441 VHARDIIEGFVRDNITEAAEFEWESQLRFYWLKKDDNLWIRQCTGV-FEYGYEYMGLNGR 1499
VH RDI + V+ +I +FEW Q RFY+ K+D + + T V F Y E++G R
Sbjct: 1965 VHQRDIFDDLVKMHIKSPTDFEWLKQSRFYF-KEDLDQTVVSITDVDFIYQNEFLGCTDR 2023
Query: 1500 LVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDF 1559
LVITPLTDR Y+T+ QAL M + D+ + LG VV NC + MDF
Sbjct: 2024 LVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDF 2083
Query: 1560 RAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLKRFTVNTDVLKP 1619
R +G+I GL Q G+WGCFDEFNRI++ VLSV + Q+ + +A + K+F +
Sbjct: 2084 RGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD----- 2138
Query: 1620 SQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTELPESVKALFRPVVCILPDLEMI 1679
G + ++ + GIF+TMNPGYAGR ELPE++K FR V ++PD ++I
Sbjct: 2139 -------------GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQII 2185
Query: 1680 CQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTAVLRMAGKLRRDSPG 1739
++ L S GFL +LA+K VLYK+ EQL+KQ HYD+GLR + +VLR G +R P
Sbjct: 2186 MRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPE 2245
Query: 1740 LSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEKDG 1799
SE+ ++MR LRDMN K V ED PLFL LI DLFPGL+ Y E AV ++ +G
Sbjct: 2246 DSELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEG 2305
Query: 1800 YVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNLGLPTKLTVVNPK 1859
+ P K+VQLYET + RH M +GP+G GKT ++ L+KAQT G P + +NPK
Sbjct: 2306 LINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQTECGRPHREMRMNPK 2365
Query: 1860 ACSVIELYGILDPVTRDWTDGLYSKIFREMNRPAEKNERRYSLFDGDVDALWIENMNSVM 1919
A + +++G LD T DWTDG++S ++R+ + A+K E + + DG VDA+WIEN+NSV+
Sbjct: 2366 AITAPQMFGRLDTATNDWTDGIFSTLWRKTLK-AKKGENIFLILDGPVDAIWIENLNSVL 2424
Query: 1920 DDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGYEPYWERWL 1979
DDNK LTLANG+RI +AP C LLFEV ++ ASPATVSR GMV++ L + P + WL
Sbjct: 2425 DDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWL 2484
Query: 1980 STRSNEEEREQLSGLFEHYVPGAINYIVFGMFGLQQQTPLKTIVPQTPLNLVMQLCYMIS 2039
R+ +E L+ L+E Y+ + P ++ N ++Q ++
Sbjct: 2485 KKRTAQEAAVFLT-LYEKVFEDTYTYMKLNL------NPKMQLL---ECNYIVQSLNLLE 2534
Query: 2040 GLLPNNEDTNMEIDKTVVECVFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVEDNPE 2099
GL+P+ E+ + + + + +F+ + SLGA + R + ++++ E
Sbjct: 2535 GLIPSKEEGGVSCVEHLHK-LFVFGLMWSLGALLELESREKLEAFLRQ----------HE 2583
Query: 2100 KKATTKHFPMGF-PTLYDYCLELTTKLWEAWDWLVPEYEHDRDM--KFPAILVPTVDTLR 2156
K P G T+Y++ + WE W+ + Y + D ++ +ILVP VD +R
Sbjct: 2584 SKLDLPEIPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIR 2642
Query: 2157 LTWLIKIMESIIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMP 2216
+LI ++I +Q T Q ++V+ K + P V + P
Sbjct: 2643 TNFLI---DTIAKQHKAVLLTGE---QGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEP 2696
Query: 2217 ------IVSHNNQCVPSLCST---RVQTL----LSHPLVDTYGTQQPIALLKLLFERKGF 2263
I S+ ++ + S R T+ ++ P+++ +G Q +++ + E +G
Sbjct: 2697 MMFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGM 2756
Query: 2264 YDRGKDLNWKNLKDIGFLAAMGKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSIL 2323
Y K ++ + D+ +AAM GGGRND+ R F+V+N PS ++ I+ I
Sbjct: 2757 YSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIG 2816
Query: 2324 KGHFE---IFPEEIQGIVEKIVQMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMC 2380
G+F+ F +I ++ +V + L++ V++ PTP+KFHYIFNLRDLSRI GM
Sbjct: 2817 CGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGML 2876
Query: 2381 LTHANYFSEKRTVVRCWRNEFTRVICDRLINQQDNELMRGHIQEHV 2426
A + T++ +++E +RVI DR I +D + H+ V
Sbjct: 2877 TIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAV 2922
Score = 572 bits (1412), Expect = e-162
Identities = 326/999 (32%), Positives = 528/999 (52%), Gaps = 23/999 (2%)
Query: 2682 AKCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKI-PEEFRPIIVEHVVHVHMSV 2740
A+ FPGL++ T+DW WP++AL+AVA+ FL+D + E + +VE + H V
Sbjct: 3166 ARSLKFPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMV 3225
Query: 2741 ARYSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQ 2800
+ + R RR +VTPK Y+ F+ Y + EK FI Q ER+ GL K+ EA+
Sbjct: 3226 SESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASES 3285
Query: 2801 LEDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVE 2860
+ L+ LAV++ +A + + + +L E++ + + + + I E
Sbjct: 3286 VAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSE 3345
Query: 2861 KXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVII--RGIKD 2918
K NDI +R A PP + + +CV+++ + I
Sbjct: 3346 KVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDP 3405
Query: 2919 V-----------SWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLDTM 2966
V SW + +M+ FL +LQ+ D I + V+ ++ + ++
Sbjct: 3406 VTMDPEKSCCKPSWGESLKLMSATGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESA 3465
Query: 2967 QQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQK 3026
+++ GLL + A+ + + A L +D Q
Sbjct: 3466 KKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQA 3525
Query: 3027 TLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSR 3086
LD + +++ AM + +L + D +++ AA L+ GLS E+ RWT+ + +R
Sbjct: 3526 ELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINR 3585
Query: 3087 LIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSG 3146
L+G+ LL T FLSY GPF+ FR ++ + W ++ R IP T + L + +
Sbjct: 3586 LVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARKIPFTENLNLISMLVDPPTIGE 3645
Query: 3147 WNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLR 3206
W +GLP D+LS+QNGI+ T+A+R+PL IDPQTQ TWIK KE +N+L+V S N F
Sbjct: 3646 WGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRT 3705
Query: 3207 QLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTF-VMLGSTEVDYDPNFRMYL 3265
LE ++ G P+L +D++E +DP +DNVLEKN ++SG TF V +G E D F++Y+
Sbjct: 3706 HLEDSLSLGRPLLIEDIHEELDPALDNVLEKNF-IKSGTTFKVKVGDKECDIMDTFKLYI 3764
Query: 3266 TTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANK 3325
TTKL NP F P AK VI++TVT++GLE+QLL V+ E+ +LE +R L+ + + NK
Sbjct: 3765 TTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNK 3824
Query: 3326 SLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRD 3385
+ LED+LL +L+ + G+++D+ L+ L TK AAEV EKL +A T I ++
Sbjct: 3825 RKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQE 3884
Query: 3386 GYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDM 3445
+RP A RGSIL+F++++M+ VN MYQ SL+ +L +F S+ ++ + + KR+ NII+
Sbjct: 3885 EFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEY 3944
Query: 3446 LTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLE-KSARSSP 3504
LT V+ Y G++E HK LF M +K++ V + IKG +L+ K+ P
Sbjct: 3945 LTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKP 4004
Query: 3505 APWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLK 3564
W+ W ++++LS P FA + + I++ + W+ WFD D PE IP+ Y + L
Sbjct: 4005 YRWILDMTWLNLVELSK-LPQ-FAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLD 4062
Query: 3565 PFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPG 3624
L+L+R + DR YI ++ E+Y P +++L+ E++ TP++ LS G
Sbjct: 4063 TCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMG 4122
Query: 3625 SDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLE 3663
SDPT + LA + + + +S+GQGQE A L++
Sbjct: 4123 SDPTNQIDALAKKLKL---ECRTISMGQGQEVHARKLIQ 4158
Score = 109 bits (262), Expect = 2e-22
Identities = 55/154 (35%), Positives = 85/154 (55%), Gaps = 2/154 (1%)
Query: 2515 RYYEDLLDYEAIYFLFQEILDEYNE--RNAKMSIVLFEDCLEHLTRTHRILRMDRGNAMX 2572
+ YE + ++ + Q ++NE R + +V F+D + HL + RI+R GNA+
Sbjct: 2964 KIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALL 3023
Query: 2573 XXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMYLQLGVDNKKTVFLFT 2632
+LA+F AG ++F+IT+TR+YN DD+K +Y G D K F+FT
Sbjct: 3024 VGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITFIFT 3083
Query: 2633 AAQILEEGFLEFINNILMIGMIPALFGDDEKDSI 2666
++I +E FLE++NN+L G I LF DE D I
Sbjct: 3084 DSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEI 3117
Score = 96.7 bits (230), Expect = 2e-18
Identities = 74/334 (22%), Positives = 156/334 (46%), Gaps = 22/334 (6%)
Query: 54 ERIFGLELKSIISDPT--QIDDVRKRVKNLVYPIRTVDFSVFVFDNKENWDVIMGDFWNE 111
E I ++ S +S+ T ID + + +N+ ++ + + + + +D DF +
Sbjct: 579 EMITVVQTYSTLSNSTIEGIDIMAIKFRNIYQGVKKKQYDI-LDPRRTEFDTDFLDFMTK 637
Query: 112 VRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEI 171
+ LE + + ++N SFG + SS++AL +L +F + + + +++ + +++ ++ E+
Sbjct: 638 INGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLNI-PCLGLEINHTIERILQYYVAEL 696
Query: 172 TAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMKQPIMKFQKVSELNECEQKKEAF 231
A + + + +PPL RN PP+AG I W R L+ ++ +PI F K S++ K
Sbjct: 697 DATKKLYHSQKDDPPLARNMPPIAGKILWVRQLYRRISEPINYFFKNSDILSSPDGKAVI 756
Query: 232 LQYKAFSKIIKEYEDTKYKEWVQDASLFCDNMMKKNILKVVFKKEDDP----VPQKARGM 287
QY S ++ E+E + W+++ S + + +F + + V + +
Sbjct: 757 RQYNKISYVLVEFEVVYHTAWIREIS-----QLHYALQATLFVRHPETGKLLVNFDPKIL 811
Query: 288 QLTAAGRAHVAKK-KASNTSLKPLDIVNKEIADKRRRDKAL-----MLMRIPGQHYENVR 341
++ + + K + + L + +K ADK L + +P + N+
Sbjct: 812 EVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPSV-FVNLM 870
Query: 342 SP--SSVSLLAKEGLTDVTWRDLTVHKLIQEYNL 373
+P V + ++GLT +TW LT+ QE L
Sbjct: 871 TPKMKKVESVLRQGLTVLTWSSLTLESFFQEVEL 904
Score = 42.7 bits (96), Expect = 0.027
Identities = 22/98 (22%), Positives = 48/98 (48%)
Query: 378 NFDKDLFLVIHEAELMEQLGFDVPSNVRDVAMQKSRLFYELEALSKIIAKYNKNASSLSP 437
NFD + V+ E + M ++ DVP + + +S+L + L ++ Y++ +
Sbjct: 805 NFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPS 864
Query: 438 SETYLMKRHLLDMERHILPGLTRITWTALGINDYIKDI 475
LM + +E + GLT +TW++L + + +++
Sbjct: 865 VFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQEV 902
>AL034345-1|CAI42433.1| 4490|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4490
Score = 849 bits (2100), Expect = 0.0
Identities = 540/1666 (32%), Positives = 877/1666 (52%), Gaps = 82/1666 (4%)
Query: 782 IKGLEDFKLVMATITQVQQMTITAEVKYRGMQEIFHMLKQHGINVTDEDLQFAKSLEASW 841
I+ L+D + M ++ ++ I ++ ++E + +L + + VT E+ + +L S+
Sbjct: 1113 IRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYSF 1172
Query: 842 GSLYQTSLFRGNTLEQTKEKFSKLNVVE-ISNFLKELDDFVEKFDNEGPATVEDDMDRGL 900
L ++ L Q + KF K N++E + F +++ +F E ++ EGP
Sbjct: 1173 NKLQSKAVSVQEDLVQVQPKF-KSNLLESVEVFREDVINFAEAYELEGPMVPNIPPQEAS 1231
Query: 901 LLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNFNRTKADYSAMDQIYKIYKAQKNA 960
++ + D+L + + EQLF P+ D+ ++T+ + + + ++Y +Y ++
Sbjct: 1232 NRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSS 1291
Query: 961 REVWAKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLMLDLKMKQFKGVVPLMVS 1020
+ + LW +++ + + + +F RKLPK ++ L L ++ F PL+
Sbjct: 1292 ISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEM 1351
Query: 1021 LKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMELHKYQDVAEEIVNHAIKELAIE 1080
+ N+AM++RHW + TG FD+ D F L N+ L K++D E+I AIKE IE
Sbjct: 1352 MTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIE 1411
Query: 1081 RGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVVKLDDDSMSLQSMAASQFIGPF 1140
+ V E W N + S + +GE +I+ ++D M L S+ ++++ PF
Sbjct: 1412 AKLTQVIENWTNQNLSFAAFKGKGELL-LKGTESGEIITLMEDSLMVLGSLLSNRYNAPF 1470
Query: 1141 LTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGGDIRTQLPEEAKKFDDIDRAFRK 1200
+Q W ++LS S+IIEEW+ Q W+YLE +FVGGDI QLP+EAK+F +ID+++ K
Sbjct: 1471 KKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIK 1530
Query: 1201 IMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASSDVTRKQINLSQAIAWADR 1260
IM + NV++CC +G + L Q +S + + +K++ + +D
Sbjct: 1531 IMQRAHENPNVINCC-VGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDP 1589
Query: 1261 ASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYVDHTNRPVAAKMISAEGEIMDF 1320
L ++ ++ Q S DNI + + +R +A +IS EGE +
Sbjct: 1590 VLLEILGQASDSHTIQPHLPAVS------DNINEVTFHAKDYDRIMA--VISREGEKIVL 1641
Query: 1321 RNVVYTEGRVEDWMNLVLVEMRHTNKFITKKAIFYYGKNWKVPRTDWILEYQGMVCLAAN 1380
N V +G VE W+ L L++M+ ++ ++ FY + ++ + V L
Sbjct: 1642 DNSVMAKGPVEIWL-LDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGLLGI 1700
Query: 1381 GVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQLDGLVVKVRQDLSSNDRLKFRTITTID 1440
+ WT ++EE LR K +++ M+ Q+ + L+ L+ + DLS DR+KF T+ TI
Sbjct: 1701 QMLWTHDSEEA-LRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIH 1759
Query: 1441 VHARDIIEGFVRDNITEAAEFEWESQLRFYWLKKDDNLWIRQCTGV-FEYGYEYMGLNGR 1499
VH RDI + V+ +I +FEW Q RFY+ K+D + + T V F Y E++G R
Sbjct: 1760 VHQRDIFDDLVKMHIKSPTDFEWLKQSRFYF-KEDLDQTVVSITDVDFIYQNEFLGCTDR 1818
Query: 1500 LVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDF 1559
LVITPLTDR Y+T+ QAL M + D+ + LG VV NC + MDF
Sbjct: 1819 LVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDF 1878
Query: 1560 RAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLKRFTVNTDVLKP 1619
R +G+I GL Q G+WGCFDEFNRI++ VLSV + Q+ + +A + K+F +
Sbjct: 1879 RGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD----- 1933
Query: 1620 SQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTELPESVKALFRPVVCILPDLEMI 1679
G + ++ + GIF+TMNPGYAGR ELPE++K FR V ++PD ++I
Sbjct: 1934 -------------GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQII 1980
Query: 1680 CQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTAVLRMAGKLRRDSPG 1739
++ L S GFL +LA+K VLYK+ EQL+KQ HYD+GLR + +VLR G +R P
Sbjct: 1981 MRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPE 2040
Query: 1740 LSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEKDG 1799
SE+ ++MR LRDMN K V ED PLFL LI DLFPGL+ Y E AV ++ +G
Sbjct: 2041 DSELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEG 2100
Query: 1800 YVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNLGLPTKLTVVNPK 1859
+ P K+VQLYET + RH M +GP+G GKT ++ L+KAQT G P + +NPK
Sbjct: 2101 LINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQTECGRPHREMRMNPK 2160
Query: 1860 ACSVIELYGILDPVTRDWTDGLYSKIFREMNRPAEKNERRYSLFDGDVDALWIENMNSVM 1919
A + +++G LD T DWTDG++S ++R+ + A+K E + + DG VDA+WIEN+NSV+
Sbjct: 2161 AITAPQMFGRLDTATNDWTDGIFSTLWRKTLK-AKKGENIFLILDGPVDAIWIENLNSVL 2219
Query: 1920 DDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGYEPYWERWL 1979
DDNK LTLANG+RI +AP C LLFEV ++ ASPATVSR GMV++ L + P + WL
Sbjct: 2220 DDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWL 2279
Query: 1980 STRSNEEEREQLSGLFEHYVPGAINYIVFGMFGLQQQTPLKTIVPQTPLNLVMQLCYMIS 2039
R+ +E L+ L+E Y+ + P ++ N ++Q ++
Sbjct: 2280 KKRTAQEAAVFLT-LYEKVFEDTYTYMKLNL------NPKMQLL---ECNYIVQSLNLLE 2329
Query: 2040 GLLPNNEDTNMEIDKTVVECVFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVEDNPE 2099
GL+P+ E+ + + + + +F+ + SLGA + R + ++++ E
Sbjct: 2330 GLIPSKEEGGVSCVEHLHK-LFVFGLMWSLGALLELESREKLEAFLRQ----------HE 2378
Query: 2100 KKATTKHFPMGF-PTLYDYCLELTTKLWEAWDWLVPEYEHDRDM--KFPAILVPTVDTLR 2156
K P G T+Y++ + WE W+ + Y + D ++ +ILVP VD +R
Sbjct: 2379 SKLDLPEIPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIR 2437
Query: 2157 LTWLIKIMESIIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMP 2216
+LI ++I +Q T Q ++V+ K + P V + P
Sbjct: 2438 TNFLI---DTIAKQHKAVLLTGE---QGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEP 2491
Query: 2217 ------IVSHNNQCVPSLCST---RVQTL----LSHPLVDTYGTQQPIALLKLLFERKGF 2263
I S+ ++ + S R T+ ++ P+++ +G Q +++ + E +G
Sbjct: 2492 MMFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGM 2551
Query: 2264 YDRGKDLNWKNLKDIGFLAAMGKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSIL 2323
Y K ++ + D+ +AAM GGGRND+ R F+V+N PS ++ I+ I
Sbjct: 2552 YSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIG 2611
Query: 2324 KGHFE---IFPEEIQGIVEKIVQMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMC 2380
G+F+ F +I ++ +V + L++ V++ PTP+KFHYIFNLRDLSRI GM
Sbjct: 2612 CGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGML 2671
Query: 2381 LTHANYFSEKRTVVRCWRNEFTRVICDRLINQQDNELMRGHIQEHV 2426
A + T++ +++E +RVI DR I +D + H+ V
Sbjct: 2672 TIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAV 2717
Score = 652 bits (1612), Expect = 0.0
Identities = 366/1107 (33%), Positives = 591/1107 (53%), Gaps = 26/1107 (2%)
Query: 2682 AKCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKI-PEEFRPIIVEHVVHVHMSV 2740
A+ FPGL++ T+DW WP++AL+AVA+ FL+D + E + +VE + H V
Sbjct: 2961 ARSLKFPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMV 3020
Query: 2741 ARYSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQ 2800
+ + R RR +VTPK Y+ F+ Y + EK FI Q ER+ GL K+ EA+
Sbjct: 3021 SESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASES 3080
Query: 2801 LEDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVE 2860
+ L+ LAV++ +A + + + +L E++ + + + + I E
Sbjct: 3081 VAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSE 3140
Query: 2861 KXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVII--RGIKD 2918
K NDI +R A PP + + +CV+++ + I
Sbjct: 3141 KVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDP 3200
Query: 2919 V-----------SWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLDTM 2966
V SW + +M+ FL +LQ+ D I + V+ ++ + ++
Sbjct: 3201 VTMDPEKSCCKPSWGESLKLMSATGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESA 3260
Query: 2967 QQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQK 3026
+++ GLL + A+ + + A L +D Q
Sbjct: 3261 KKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQA 3320
Query: 3027 TLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSR 3086
LD + +++ AM + +L + D +++ AA L+ GLS E+ RWT+ + +R
Sbjct: 3321 ELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINR 3380
Query: 3087 LIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSG 3146
L+G+ LL T FLSY GPF+ FR ++ + W ++ R IP T + L + +
Sbjct: 3381 LVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARKIPFTENLNLISMLVDPPTIGE 3440
Query: 3147 WNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLR 3206
W +GLP D+LS+QNGI+ T+A+R+PL IDPQTQ TWIK KE +N+L+V S N F
Sbjct: 3441 WGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRT 3500
Query: 3207 QLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTF-VMLGSTEVDYDPNFRMYL 3265
LE ++ G P+L +D++E +DP +DNVLEKN ++SG TF V +G E D F++Y+
Sbjct: 3501 HLEDSLSLGRPLLIEDIHEELDPALDNVLEKNF-IKSGTTFKVKVGDKECDIMDTFKLYI 3559
Query: 3266 TTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANK 3325
TTKL NP F P AK VI++TVT++GLE+QLL V+ E+ +LE +R L+ + + NK
Sbjct: 3560 TTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNK 3619
Query: 3326 SLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRD 3385
+ LED+LL +L+ + G+++D+ L+ L TK AAEV EKL +A T I ++
Sbjct: 3620 RKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQE 3679
Query: 3386 GYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDM 3445
+RP A RGSIL+F++++M+ VN MYQ SL+ +L +F S+ ++ + + KR+ NII+
Sbjct: 3680 EFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEY 3739
Query: 3446 LTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLE-KSARSSP 3504
LT V+ Y G++E HK LF M +K++ V + IKG +L+ K+ P
Sbjct: 3740 LTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKP 3799
Query: 3505 APWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLK 3564
W+ W ++++LS P FA + + I++ + W+ WFD D PE IP+ Y + L
Sbjct: 3800 YRWILDMTWLNLVELSK-LPQ-FAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLD 3857
Query: 3565 PFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPG 3624
L+L+R + DR YI ++ E+Y P +++L+ E++ TP++ LS G
Sbjct: 3858 TCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMG 3917
Query: 3625 SDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFL 3684
SDPT + LA + + + +S+GQGQE A L++ ++ G W++LQNCHL + F+
Sbjct: 3918 SDPTNQIDALAKKLKL---ECRTISMGQGQEVHARKLIQMSMQQGGWVLLQNCHLGLEFM 3974
Query: 3685 RELEKQLELMTKPHPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLNLRNTYFKMR 3741
EL + L +R+W+TT+P FPI +LQ SLK EPP G++ L+ T+ +
Sbjct: 3975 EELLETLITTEASDDSFRVWITTEPHDRFPITLLQTSLKFTNEPPQGVRAGLKRTFAGIN 4034
Query: 3742 ARALEECPHPQFKKLVYVLAFFHAVVQ 3768
L+ P +K ++Y +AF H+ VQ
Sbjct: 4035 QDLLDISNLPMWKPMLYTVAFLHSTVQ 4061
Score = 192 bits (469), Expect = 2e-47
Identities = 128/408 (31%), Positives = 201/408 (49%), Gaps = 17/408 (4%)
Query: 3745 LEECPHPQFKKLVYVLAFFHAVVQVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFH 3804
L+EC KK V + + +V YGG + + E +F+ F
Sbjct: 4093 LDEC---DIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMFEP--SFC 4147
Query: 3805 FYKDYAFDYVIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIE 3864
FY Y IP D+Y ++I +LP + PEVFGLHPNA+I Y S + +
Sbjct: 4148 FYTGYK----IPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQSNTASAVLETITN 4203
Query: 3865 LQPQTSEAGGAMSREDFIDNIAVDVLSKLPTLYEIWRVRKQ-FEM-NITPTLVVLLQELE 3922
+QP+ S G +RE + ++ D+LSKLP Y V+ + +M ++ + L QE++
Sbjct: 4204 IQPKESGGGVGETREAIVYRLSEDMLSKLPPDYIPHEVKSRLIKMGHLNSMNIFLRQEID 4263
Query: 3923 RFNRLISRMGSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGW 3982
R R+IS + S+LS L+ A+ G I M L + ++++ ++PQ+W+ ++ LG W
Sbjct: 4264 RMQRVISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQLWKRVS-WDSSTLGFW 4322
Query: 3983 MDHFIARTKQYTDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYT-WPLDRSTQFTKV 4041
+ R Q++ W P V W++G P+ +L A Q R + W LD T +V
Sbjct: 4323 FTELLERNAQFSTWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDTVTIHNEV 4382
Query: 4042 TSWVSADEIEERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHK 4101
+ +EI P G Y+ GLY++GA WD G L S PKVL T+LP+++I I
Sbjct: 4383 LR-QTKEEITSPPGEGVYIYGLYMDGAAWDRRNGKLMESTPKVLFTQLPVLHIFAINSTA 4441
Query: 4102 LKLQNTLRTPVYTTSQRRNAMGVGLVFESDLWTTEHCSHWILQGVCLI 4149
K P+Y +R + + +V+ L T HWIL+GV L+
Sbjct: 4442 PKDPKLYVCPIYKKPRRTDLTFITVVY---LRTVLSPDHWILRGVALL 4486
Score = 109 bits (262), Expect = 2e-22
Identities = 55/154 (35%), Positives = 85/154 (55%), Gaps = 2/154 (1%)
Query: 2515 RYYEDLLDYEAIYFLFQEILDEYNE--RNAKMSIVLFEDCLEHLTRTHRILRMDRGNAMX 2572
+ YE + ++ + Q ++NE R + +V F+D + HL + RI+R GNA+
Sbjct: 2759 KIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALL 2818
Query: 2573 XXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMYLQLGVDNKKTVFLFT 2632
+LA+F AG ++F+IT+TR+YN DD+K +Y G D K F+FT
Sbjct: 2819 VGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITFIFT 2878
Query: 2633 AAQILEEGFLEFINNILMIGMIPALFGDDEKDSI 2666
++I +E FLE++NN+L G I LF DE D I
Sbjct: 2879 DSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEI 2912
Score = 96.7 bits (230), Expect = 2e-18
Identities = 74/334 (22%), Positives = 156/334 (46%), Gaps = 22/334 (6%)
Query: 54 ERIFGLELKSIISDPT--QIDDVRKRVKNLVYPIRTVDFSVFVFDNKENWDVIMGDFWNE 111
E I ++ S +S+ T ID + + +N+ ++ + + + + +D DF +
Sbjct: 374 EMITVVQTYSTLSNSTIEGIDIMAIKFRNIYQGVKKKQYDI-LDPRRTEFDTDFLDFMTK 432
Query: 112 VRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEI 171
+ LE + + ++N SFG + SS++AL +L +F + + + +++ + +++ ++ E+
Sbjct: 433 INGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLNI-PCLGLEINHTIERILQYYVAEL 491
Query: 172 TAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMKQPIMKFQKVSELNECEQKKEAF 231
A + + + +PPL RN PP+AG I W R L+ ++ +PI F K S++ K
Sbjct: 492 DATKKLYHSQKDDPPLARNMPPIAGKILWVRQLYRRISEPINYFFKNSDILSSPDGKAVI 551
Query: 232 LQYKAFSKIIKEYEDTKYKEWVQDASLFCDNMMKKNILKVVFKKEDDP----VPQKARGM 287
QY S ++ E+E + W+++ S + + +F + + V + +
Sbjct: 552 RQYNKISYVLVEFEVVYHTAWIREIS-----QLHYALQATLFVRHPETGKLLVNFDPKIL 606
Query: 288 QLTAAGRAHVAKK-KASNTSLKPLDIVNKEIADKRRRDKAL-----MLMRIPGQHYENVR 341
++ + + K + + L + +K ADK L + +P + N+
Sbjct: 607 EVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPSV-FVNLM 665
Query: 342 SP--SSVSLLAKEGLTDVTWRDLTVHKLIQEYNL 373
+P V + ++GLT +TW LT+ QE L
Sbjct: 666 TPKMKKVESVLRQGLTVLTWSSLTLESFFQEVEL 699
Score = 42.7 bits (96), Expect = 0.027
Identities = 22/98 (22%), Positives = 48/98 (48%)
Query: 378 NFDKDLFLVIHEAELMEQLGFDVPSNVRDVAMQKSRLFYELEALSKIIAKYNKNASSLSP 437
NFD + V+ E + M ++ DVP + + +S+L + L ++ Y++ +
Sbjct: 600 NFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPS 659
Query: 438 SETYLMKRHLLDMERHILPGLTRITWTALGINDYIKDI 475
LM + +E + GLT +TW++L + + +++
Sbjct: 660 VFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQEV 697
>AF356519-1|AAK60620.1| 4490|Homo sapiens axonemal dynein heavy chain
8 protein.
Length = 4490
Score = 849 bits (2100), Expect = 0.0
Identities = 540/1666 (32%), Positives = 877/1666 (52%), Gaps = 82/1666 (4%)
Query: 782 IKGLEDFKLVMATITQVQQMTITAEVKYRGMQEIFHMLKQHGINVTDEDLQFAKSLEASW 841
I+ L+D + M ++ ++ I ++ ++E + +L + + VT E+ + +L S+
Sbjct: 1113 IRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESEAVDTLRYSF 1172
Query: 842 GSLYQTSLFRGNTLEQTKEKFSKLNVVE-ISNFLKELDDFVEKFDNEGPATVEDDMDRGL 900
L ++ L Q + KF K N++E + F +++ +F E ++ EGP
Sbjct: 1173 NKLQSKAVSVQEDLVQVQPKF-KSNLLESVKVFREDVINFAEAYELEGPMVPNIPPQEAS 1231
Query: 901 LLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNFNRTKADYSAMDQIYKIYKAQKNA 960
++ + D+L + + EQLF P+ D+ ++T+ + + + ++Y +Y ++
Sbjct: 1232 NRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMSS 1291
Query: 961 REVWAKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLMLDLKMKQFKGVVPLMVS 1020
+ + LW +++ + + + +F RKLPK ++ L L ++ F PL+
Sbjct: 1292 ISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDFSESCPLLEM 1351
Query: 1021 LKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMELHKYQDVAEEIVNHAIKELAIE 1080
+ N+AM++RHW + TG FD+ D F L N+ L K++D E+I AIKE IE
Sbjct: 1352 MTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICISAIKEKDIE 1411
Query: 1081 RGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVVKLDDDSMSLQSMAASQFIGPF 1140
+ V E W N + S + +GE +I+ ++D M L S+ ++++ PF
Sbjct: 1412 AKLTQVIENWTNQNLSFAAFKGKGELL-LKGTESGEIITLMEDSLMVLGSLLSNRYNAPF 1470
Query: 1141 LTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGGDIRTQLPEEAKKFDDIDRAFRK 1200
+Q W ++LS S+IIEEW+ Q W+YLE +FVGGDI QLP+EAK+F +ID+++ K
Sbjct: 1471 KKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIK 1530
Query: 1201 IMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASSDVTRKQINLSQAIAWADR 1260
IM + NV++CC +G + L Q +S + + +K++ + +D
Sbjct: 1531 IMQRAHENPNVINCC-VGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDP 1589
Query: 1261 ASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYVDHTNRPVAAKMISAEGEIMDF 1320
L ++ ++ Q S DNI + + +R +A +IS EGE +
Sbjct: 1590 VLLEILGQASDSHTIQPHLPAVS------DNINEVTFHTKDYDRIMA--VISREGEKIVL 1641
Query: 1321 RNVVYTEGRVEDWMNLVLVEMRHTNKFITKKAIFYYGKNWKVPRTDWILEYQGMVCLAAN 1380
N V +G VE W+ L L++M+ ++ ++ FY + ++ + V L
Sbjct: 1642 DNSVMAKGPVEIWL-LDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGLLGI 1700
Query: 1381 GVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQLDGLVVKVRQDLSSNDRLKFRTITTID 1440
+ WT ++EE LR K +++ M+ Q+ + L+ L+ + DLS DR+KF T+ TI
Sbjct: 1701 QMLWTHDSEEA-LRNAKDDRKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLITIH 1759
Query: 1441 VHARDIIEGFVRDNITEAAEFEWESQLRFYWLKKDDNLWIRQCTGV-FEYGYEYMGLNGR 1499
VH RDI + V+ +I +FEW Q RFY+ K+D + + T V F Y E++G R
Sbjct: 1760 VHQRDIFDDLVKMHIKSPTDFEWLKQSRFYF-KEDLDQTVVSITDVDFIYQNEFLGCTDR 1818
Query: 1500 LVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDF 1559
LVITPLTDR Y+T+ QAL M + D+ + LG VV NC + MDF
Sbjct: 1819 LVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDF 1878
Query: 1560 RAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLKRFTVNTDVLKP 1619
R +G+I GL Q G+WGCFDEFNRI++ VLSV + Q+ + +A + K+F +
Sbjct: 1879 RGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSD----- 1933
Query: 1620 SQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTELPESVKALFRPVVCILPDLEMI 1679
G + ++ + GIF+TMNPGYAGR ELPE++K FR V ++PD ++I
Sbjct: 1934 -------------GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQII 1980
Query: 1680 CQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTAVLRMAGKLRRDSPG 1739
++ L S GFL +LA+K VLYK+ EQL+KQ HYD+GLR + +VLR G +R P
Sbjct: 1981 MRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPE 2040
Query: 1740 LSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEKDG 1799
SE+ ++MR LRDMN K V ED PLFL LI DLFPGL+ Y E AV ++ +G
Sbjct: 2041 DSELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEG 2100
Query: 1800 YVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNLGLPTKLTVVNPK 1859
+ P K+VQLYET + RH M +GP+G GKT ++ L+KAQT G P + +NPK
Sbjct: 2101 LINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQTECGRPHREMRMNPK 2160
Query: 1860 ACSVIELYGILDPVTRDWTDGLYSKIFREMNRPAEKNERRYSLFDGDVDALWIENMNSVM 1919
A + +++G LD T DWTDG++S ++R+ + A+K E + + DG VDA+WIEN+NSV+
Sbjct: 2161 AITAPQMFGRLDTATNDWTDGIFSTLWRKTLK-AKKGENIFLILDGPVDAIWIENLNSVL 2219
Query: 1920 DDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGYEPYWERWL 1979
DDNK LTLANG+RI +AP C LLFEV ++ ASPATVSR GMV++ L + P + WL
Sbjct: 2220 DDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWL 2279
Query: 1980 STRSNEEEREQLSGLFEHYVPGAINYIVFGMFGLQQQTPLKTIVPQTPLNLVMQLCYMIS 2039
R+ +E L+ L+E Y+ + P ++ N ++Q ++
Sbjct: 2280 KKRTAQEAAVFLT-LYEKVFEDTYTYMKLNL------NPKMQLL---ECNYIVQSLNLLE 2329
Query: 2040 GLLPNNEDTNMEIDKTVVECVFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVEDNPE 2099
GL+P+ E+ + + + + +F+ + SLGA + R + ++++ E
Sbjct: 2330 GLIPSKEEGGVSCVEHLHK-LFVFGLMWSLGALLELESREKLEAFLRQ----------HE 2378
Query: 2100 KKATTKHFPMGF-PTLYDYCLELTTKLWEAWDWLVPEYEHDRDM--KFPAILVPTVDTLR 2156
K P G T+Y++ + WE W+ + Y + D ++ +ILVP VD +R
Sbjct: 2379 SKLDLPEIPKGSNQTMYEFYV-TDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDNIR 2437
Query: 2157 LTWLIKIMESIIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMP 2216
+LI ++I +Q T Q ++V+ K + P V + P
Sbjct: 2438 TNFLI---DTIAKQHKAVLLTGE---QGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEP 2491
Query: 2217 ------IVSHNNQCVPSLCST---RVQTL----LSHPLVDTYGTQQPIALLKLLFERKGF 2263
I S+ ++ + S R T+ ++ P+++ +G Q +++ + E +G
Sbjct: 2492 MMFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGM 2551
Query: 2264 YDRGKDLNWKNLKDIGFLAAMGKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSIL 2323
Y K ++ + D+ +AAM GGGRND+ R F+V+N PS ++ I+ I
Sbjct: 2552 YSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIG 2611
Query: 2324 KGHFE---IFPEEIQGIVEKIVQMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMC 2380
G+F+ F +I ++ +V + L++ V++ PTP+KFHYIFNLRDLSRI GM
Sbjct: 2612 CGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGML 2671
Query: 2381 LTHANYFSEKRTVVRCWRNEFTRVICDRLINQQDNELMRGHIQEHV 2426
A + T++ +++E +RVI DR I +D + H+ V
Sbjct: 2672 TIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAV 2717
Score = 652 bits (1611), Expect = 0.0
Identities = 366/1107 (33%), Positives = 591/1107 (53%), Gaps = 26/1107 (2%)
Query: 2682 AKCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKI-PEEFRPIIVEHVVHVHMSV 2740
A+ FPGL++ T+DW WP++AL+AVA+ FL+D + E + +VE + H V
Sbjct: 2961 ARSLKFPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMV 3020
Query: 2741 ARYSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQ 2800
+ + R RR +VTPK Y+ F+ Y + EK FI Q ER+ GL K+ EA+
Sbjct: 3021 SESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASES 3080
Query: 2801 LEDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVE 2860
+ L+ LAV++ +A + + + +L E++ + + + + I E
Sbjct: 3081 VAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSE 3140
Query: 2861 KXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVII--RGIKD 2918
K NDI +R A PP + + +CV+++ + I
Sbjct: 3141 KVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDP 3200
Query: 2919 V-----------SWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLDTM 2966
V SW + +M+ FL +LQ+ D I + V+ ++ + ++
Sbjct: 3201 VTMDPEKSCCKPSWGESLKLMSATGFLWSLQQFPKDTINEETVELLQPYFNMDDYTFESA 3260
Query: 2967 QQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQK 3026
+++ GLL + A+ + + A L +D Q
Sbjct: 3261 KKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQA 3320
Query: 3027 TLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSR 3086
LD + +++ AM + +L + D +++ AA L+ GLS E+ RWT+ + +R
Sbjct: 3321 ELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINR 3380
Query: 3087 LIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSG 3146
L+G+ LL T FLSY GPF+ FR ++ + W ++ R IP T + L + +
Sbjct: 3381 LVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARKIPFTENLNLISMLVDPPTIGE 3440
Query: 3147 WNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLR 3206
W +GLP D+LS+QNGI+ T+A+R+PL IDPQTQ TWIK KE +N+L+V S N F
Sbjct: 3441 WGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNRKYFRT 3500
Query: 3207 QLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTF-VMLGSTEVDYDPNFRMYL 3265
LE ++ G P+L +D++E +DP +DNVLEKN ++SG TF V +G E D F++Y+
Sbjct: 3501 HLEDSLSLGRPLLIEDIHEELDPALDNVLEKNF-IKSGTTFKVKVGDKECDIMDTFKLYI 3559
Query: 3266 TTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANK 3325
TTKL NP F P AK VI++TVT++GLE+QLL V+ E+ +LE +R L+ + + NK
Sbjct: 3560 TTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNK 3619
Query: 3326 SLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRD 3385
+ LED+LL +L+ + G+++D+ L+ L TK AAEV EKL +A T I ++
Sbjct: 3620 RKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQE 3679
Query: 3386 GYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDM 3445
+RP A RGSIL+F++++M+ VN MYQ SL+ +L +F S+ ++ + + KR+ NII+
Sbjct: 3680 EFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEY 3739
Query: 3446 LTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLE-KSARSSP 3504
LT V+ Y G++E HK LF M +K++ V + IKG +L+ K+ P
Sbjct: 3740 LTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKP 3799
Query: 3505 APWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLK 3564
W+ W ++++LS P FA + + I++ + W+ WFD D PE IP+ Y + L
Sbjct: 3800 YRWILDMTWLNLVELSK-LPQ-FAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLD 3857
Query: 3565 PFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPG 3624
L+L+R + DR YI ++ E+Y P +++L+ E++ TP++ LS G
Sbjct: 3858 TCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMG 3917
Query: 3625 SDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFL 3684
SDPT + LA + + + +S+GQGQE A L++ ++ G W++LQNCHL + F+
Sbjct: 3918 SDPTNQIDALAKKLKL---ECRTISMGQGQEVHARKLIQMSMQQGGWVLLQNCHLGLEFM 3974
Query: 3685 RELEKQLELMTKPHPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLNLRNTYFKMR 3741
EL + L +R+W+TT+P FPI +LQ SLK EPP G++ L+ T+ +
Sbjct: 3975 EELLETLITTEASDDSFRVWITTEPHDRFPITLLQTSLKFTNEPPQGVRAGLKRTFAGIN 4034
Query: 3742 ARALEECPHPQFKKLVYVLAFFHAVVQ 3768
L+ P +K ++Y +AF H+ VQ
Sbjct: 4035 QDLLDISNLPMWKPMLYTVAFLHSTVQ 4061
Score = 190 bits (462), Expect = 1e-46
Identities = 127/408 (31%), Positives = 200/408 (49%), Gaps = 17/408 (4%)
Query: 3745 LEECPHPQFKKLVYVLAFFHAVVQVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFH 3804
L+EC KK V + + +V YG + + E +F+ F
Sbjct: 4093 LDEC---DIKKGVSWNTVRYMIGEVQYGDRVTDDFDKRLLNCFARVWFSEKMFEP--SFC 4147
Query: 3805 FYKDYAFDYVIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIE 3864
FY Y IP D+Y ++I +LP + PEVFGLHPNA+I Y S + +
Sbjct: 4148 FYTGYK----IPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQSNTASAVLETITN 4203
Query: 3865 LQPQTSEAGGAMSREDFIDNIAVDVLSKLPTLYEIWRVRKQ-FEM-NITPTLVVLLQELE 3922
+QP+ S G +RE + ++ D+LSKLP Y V+ + +M ++ + L QE++
Sbjct: 4204 IQPKESGGGVGETREAIVYRLSEDMLSKLPPDYIPHEVKSRLIKMGHLNSMNIFLRQEID 4263
Query: 3923 RFNRLISRMGSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGW 3982
R R+IS + S+LS L+ A+ G I M L + ++++ ++PQ+W+ ++ LG W
Sbjct: 4264 RMQRVISVLRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQLWKRVS-WDSSTLGFW 4322
Query: 3983 MDHFIARTKQYTDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYT-WPLDRSTQFTKV 4041
+ R Q++ W P V W++G P+ +L A Q R + W LD T +V
Sbjct: 4323 FTELLERNAQFSTWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDTVTIHNEV 4382
Query: 4042 TSWVSADEIEERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHK 4101
+ +EI P G Y+ GLY++GA WD G L S PKVL T+LP+++I I
Sbjct: 4383 LR-QTKEEITSPPGEGVYIYGLYMDGAAWDRRNGKLMESTPKVLFTQLPVLHIFAINSTA 4441
Query: 4102 LKLQNTLRTPVYTTSQRRNAMGVGLVFESDLWTTEHCSHWILQGVCLI 4149
K P+Y +R + + +V+ L T HWIL+GV L+
Sbjct: 4442 PKDPKLYVCPIYKKPRRTDLTFITVVY---LRTVLSPDHWILRGVALL 4486
Score = 109 bits (262), Expect = 2e-22
Identities = 55/154 (35%), Positives = 85/154 (55%), Gaps = 2/154 (1%)
Query: 2515 RYYEDLLDYEAIYFLFQEILDEYNE--RNAKMSIVLFEDCLEHLTRTHRILRMDRGNAMX 2572
+ YE + ++ + Q ++NE R + +V F+D + HL + RI+R GNA+
Sbjct: 2759 KIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALL 2818
Query: 2573 XXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMYLQLGVDNKKTVFLFT 2632
+LA+F AG ++F+IT+TR+YN DD+K +Y G D K F+FT
Sbjct: 2819 VGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITFIFT 2878
Query: 2633 AAQILEEGFLEFINNILMIGMIPALFGDDEKDSI 2666
++I +E FLE++NN+L G I LF DE D I
Sbjct: 2879 DSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEI 2912
Score = 97.1 bits (231), Expect = 1e-18
Identities = 75/334 (22%), Positives = 156/334 (46%), Gaps = 22/334 (6%)
Query: 54 ERIFGLELKSIISDPT--QIDDVRKRVKNLVYPIRTVDFSVFVFDNKENWDVIMGDFWNE 111
E I ++ S +S+ T ID + + +N+ ++ + + + + +D DF +
Sbjct: 374 EMITVVQTYSTLSNSTIEGIDIMAIKFRNIYQGVKKKQYDI-LDPRRTEFDTDFLDFMTK 432
Query: 112 VRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEI 171
+ LE + + ++N SFG + SS++AL +L +F + + + +++ + +++ ++ E+
Sbjct: 433 INGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLNI-PCLGLEINHTIERILQYYVAEL 491
Query: 172 TAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMKQPIMKFQKVSELNECEQKKEAF 231
A + + + +PPL RN PP+AG I W R L+ ++ +PI F K S++ K
Sbjct: 492 DATKKLYHSQKDDPPLARNMPPIAGKILWVRQLYRRISEPINYFFKNSDILSSPDGKAVI 551
Query: 232 LQYKAFSKIIKEYEDTKYKEWVQDASLFCDNMMKKNILKVVFKKEDDP----VPQKARGM 287
QY S ++ E+E + WV++ S + + +F + + V + +
Sbjct: 552 RQYNKISYVLVEFEVVYHTAWVREIS-----QLHYALQATLFVRHPETGKLLVNFDPKIL 606
Query: 288 QLTAAGRAHVAKK-KASNTSLKPLDIVNKEIADKRRRDKAL-----MLMRIPGQHYENVR 341
++ + + K + + L + +K ADK L + +P + N+
Sbjct: 607 EVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPSV-FVNLM 665
Query: 342 SP--SSVSLLAKEGLTDVTWRDLTVHKLIQEYNL 373
+P V + ++GLT +TW LT+ QE L
Sbjct: 666 TPKMKKVESVLRQGLTVLTWSSLTLESFFQEVEL 699
Score = 42.7 bits (96), Expect = 0.027
Identities = 22/98 (22%), Positives = 48/98 (48%)
Query: 378 NFDKDLFLVIHEAELMEQLGFDVPSNVRDVAMQKSRLFYELEALSKIIAKYNKNASSLSP 437
NFD + V+ E + M ++ DVP + + +S+L + L ++ Y++ +
Sbjct: 600 NFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESKLKADKLYLQGLLQYYDELCQEVPS 659
Query: 438 SETYLMKRHLLDMERHILPGLTRITWTALGINDYIKDI 475
LM + +E + GLT +TW++L + + +++
Sbjct: 660 VFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQEV 697
>AB002355-1|BAA21573.2| 2992|Homo sapiens KIAA0357 protein.
Length = 2992
Score = 788 bits (1948), Expect = 0.0
Identities = 470/1362 (34%), Positives = 724/1362 (53%), Gaps = 70/1362 (5%)
Query: 1069 IVNHAIKELAIERGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVVKLDDDSMSL 1128
IV+ A KE+ +E+ +K++Q TWA + F H L +D++ L+D+ + L
Sbjct: 5 IVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHPRTNVP---LLCSDEDLIEVLEDNQVQL 61
Query: 1129 QSMAASQFIGPFLTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGG-DIRTQLPEE 1187
Q++ S+++ FL V W+ +LS + +I W QR W +LE IF G DIR QLP++
Sbjct: 62 QNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQD 121
Query: 1188 AKKFDDIDRAFRKIMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASSDVTRK 1247
+K+F+ ID F+++ D K NVV G E+ ++ L + + D R
Sbjct: 122 SKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRL 181
Query: 1248 QINLSQAIAWADRASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYVDHTNRPVA 1307
++ +D + S+ A Q +R + +FDN+ + +D + P
Sbjct: 182 AFPRFYFLSSSDLLDIL----SNGTAPQQVQRH----LSKLFDNMAKMRFQLDASGEPTK 233
Query: 1308 AK--MISAEGEIMDFRNVVYTEGRVEDWMNLVLVEMRHTNKFITKKAIFYYGKNWKVPRT 1365
M S E E + F G+VE W+N VL M+ T + + + Y + PR
Sbjct: 234 TSLGMYSKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVTAYEEK---PRE 290
Query: 1366 DWILEYQGMVCLAANGVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQLDGLVVKVRQDL 1425
W+ ++ V L +WWT E F R+++G + AMK++ ++Q QL L+ + L
Sbjct: 291 QWLFDHPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQLKTLITMLIGQL 350
Query: 1426 SSNDRLKFRTITTIDVHARDIIEGFVRDNITEAAEFEWESQLRFYWLKKDDNLWIRQCTG 1485
S DR K TI TIDVHARD++ + + A F W SQLR W + + + C
Sbjct: 351 SKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDEVKHCFANICDA 410
Query: 1486 VFEYGYEYMGLNGRLVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALG 1545
F Y YEY+G RLVITPLTDR Y+T+TQ+L + + DL +ALG
Sbjct: 411 QFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALG 470
Query: 1546 LLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLM 1605
+L V NC E MD+++ G I GL Q GAWGCFDEFNRI + VLSV++ Q++ I+ A+
Sbjct: 471 ILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRD 530
Query: 1606 KLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTELPESVKAL 1665
K + F+ G+EI+++ VGIFITMNPGYAGRTELPE++K+L
Sbjct: 531 KKQWFSF-------------------LGEEISLNPSVGIFITMNPGYAGRTELPENLKSL 571
Query: 1666 FRPVVCILPDLEMICQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTA 1725
FRP ++PD E+IC+I L ++GF+ A+ LA+K LY++ +E LSKQ HYDWGLRA+ +
Sbjct: 572 FRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKS 631
Query: 1726 VLRMAGKLRRDSPGLSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYP 1785
VL +AG L+R P E VLMR+LRD N PK V +D+P+F+GLI DLFP L+ PR P
Sbjct: 632 VLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPALDVPRRRDP 691
Query: 1786 EFNAAVLEVLEKDGYVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQT 1845
F A V + + + V KVVQL E + RH +VG G GK+ +L L K
Sbjct: 692 NFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQVLRSLHKTYQ 751
Query: 1846 NLGLPTKLTVVNPKACSVIELYGILDPVTRDWTDGLYSKIFREMNRPAEKNERRYSLFDG 1905
+ T +NPKA + EL+GI++P T +W DGL+S I RE+ ++ L DG
Sbjct: 752 IMKRRPVWTDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANTTHDGP-KWILLDG 810
Query: 1906 DVDALWIENMNSVMDDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVD 1965
D+D +WIE++N+VMDDNK+LTLA+ ERI L P LLFE+ L A+PATVSRAG+++++
Sbjct: 811 DIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVSRAGILYIN 870
Query: 1966 PKNLGYEPYWERWLSTRSNEEEREQLSGLFEHYVPGAINYIVFGMFGLQQQTPLKTIVPQ 2025
P +LG+ P W+ R + ER L+ LF+ Y+P ++ + +T K I+P
Sbjct: 871 PADLGWNPPVSSWIEKREIQTERANLTILFDKYLPTCLDTL---------RTRFKKIIPI 921
Query: 2026 TPLNLVMQLCYMISGLLPNNEDTNMEIDKTVVECVFMVSMYNSLGAAIVDNGRYDFDNYI 2085
++V +C+++ LL ED + K + E F+ + + G A+V + D+
Sbjct: 922 PEQSMVQMVCHLLECLL-TTEDIPADCPKEIYEHYFVFAAIWAFGGAMVQDQLVDYRAEF 980
Query: 2086 KKACPMMLVEDNPEKKATTKHFPMGFPTLYDYCLELTTKLWEAWDWLVPEYEHDRDMKFP 2145
K L E T FP T++DY ++ TK +E W LVP++E D +M
Sbjct: 981 SK---WWLTE------FKTVKFP-SQGTIFDYYIDPETKKFEPWSKLVPQFEFDPEMPLQ 1030
Query: 2146 AILVPTVDTLRLTWLIKIM---ESIIQQMNFSSRTSSMDVQRNLESVVEKR--TKDT-FG 2199
A LV T +T+R+ + ++ + + + + + S+ V L S+ + K+ F
Sbjct: 1031 ACLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGKSVLVGAKLASLDPEAYLVKNVPFN 1090
Query: 2200 PPVGKRMLVFIDDMNMPIVSHNNQCVPSLCSTRVQTL--LSHPLVDTYGTQQPIALLKLL 2257
ML + + + + N P + + ++ P VD YGT QP +++
Sbjct: 1091 YYTTSAMLQAVLEKPLEKKAGRNYGPPG-NKKLIYFIDDMNMPEVDAYGTVQPHTIIRQH 1149
Query: 2258 FERKGFYDRGKDLNWKNLKDIGFLAAMGKAGGGRNDVDPRFISMFSVYNLQFPSENTLRH 2317
+ +YDR K L+ K + ++ +++ M G ++PR FSV+ L FP + L
Sbjct: 1150 LDYGHWYDRSK-LSLKEITNVQYVSCMNPTAGSFT-INPRLQRHFSVFVLSFPGADALSS 1207
Query: 2318 IYVSILKGHFEI--FPEEIQGIVEKIVQMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRI 2375
IY IL H ++ FP +Q + ++ + L ++ I PT KFHYIFNLRD + I
Sbjct: 1208 IYSIILTQHLKLGNFPASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFANI 1267
Query: 2376 AAGMCLTHANYFSEKRTVVRCWRNEFTRVICDRLINQQDNEL 2417
G+ + ++R + +E RV D+++ ++D +L
Sbjct: 1268 FQGILFSSVECVKSTWDLIRLYLHESNRVYRDKMVEEKDFDL 1309
Score = 716 bits (1771), Expect = 0.0
Identities = 450/1482 (30%), Positives = 754/1482 (50%), Gaps = 52/1482 (3%)
Query: 2683 KCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKIPEEFRPIIVEHVVHVHMSVAR 2742
+ R FP +VN T I W WP+QAL +V+ FL + + I + I + + VH SV +
Sbjct: 1547 RSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVKQSISKFMAFVHTSVNQ 1606
Query: 2743 YSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQLE 2802
S +L +R NY TPK +++F+ Y +LL+ + + ERL+ GL K+ + Q++
Sbjct: 1607 TSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENGLLKLHSTSAQVD 1666
Query: 2803 DLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVEKX 2862
DL AKLA Q+V + ++ ++ + L++ + T+ ++ + ++
Sbjct: 1667 DLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIMLEVKQKQK 1726
Query: 2863 XXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVII-----RGIK 2917
K ++TE++SF +PP AV V V+++ R K
Sbjct: 1727 DCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLMAPRGRVPK 1786
Query: 2918 DVSWKGAKGMMADPN-FLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLDTMQQISKAGYG 2975
D SWK AK MA + FL +L N + I + +KA++ +++ + + + S A G
Sbjct: 1787 DRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRPYLQDPEFNPEFVATKSYAAAG 1846
Query: 2976 LLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQKTLDGLNNRY 3035
L +V ++ + + A LA++ +I L + L L R+
Sbjct: 1847 LCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAIKAKIAHLNENLAKLTARF 1906
Query: 3036 ETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSRLIGNCLLAT 3095
E A + + Q+E ++ + A++L+ GL+SE RW + + ++ L G+ LL T
Sbjct: 1907 EKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWADAVQNFKQQERTLCGDILLIT 1966
Query: 3096 SFLSYTGPFSFSFRQTMIYEDWLGDV--MERGIPLTLPFTIERNLTNEVEVSGWNSEGLP 3153
+F+SY G F+ +RQ+++ W + ++ IP+T R L ++ +V+ W +EGLP
Sbjct: 1967 AFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTPALDPLRMLMDDADVAAWQNEGLP 2026
Query: 3154 PDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLRQLEMAIK 3213
D +SV+N + R+PL +DPQ Q + WIK K ++ L+V +L+ +E A++
Sbjct: 2027 ADRMSVENATILINCERWPLMVDPQLQGIKWIKNKYGED-LRVTQIGQKGYLQIIEQALE 2085
Query: 3214 YGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPNFRMYLTTKLANPQ 3273
G VL +++ E IDPV+ +L + + ++ GR F+ +G E +Y+P FR+ L TKLANP
Sbjct: 2086 AGAVVLIENLEESIDPVLGPLLGREV-IKKGR-FIKIGDKECEYNPKFRLILHTKLANPH 2143
Query: 3274 FNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANKSLLSGLED 3333
+ P A+A +IN+TVT GLEDQLL+ VV ER DLE+ + L + + K L LED
Sbjct: 2144 YQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKSDLTKQQNGFKITLKTLED 2203
Query: 3334 SLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRDGYRPVAKR 3393
SLL L++++GN L LV LE TK AAEV +K++ A+ T I + R+ YRP A R
Sbjct: 2204 SLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEAKVTEVKINEAREHYRPAAAR 2263
Query: 3394 GSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDMLTKNVYDY 3453
S+L+F+++D++ ++ MYQ+SL ++ VF ++ +A P+ L +R+ N+ID +T +VY Y
Sbjct: 2264 ASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQY 2323
Query: 3454 GCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLEKSARSSPAPWMPAQGW 3513
G+FE KL + Q+ ++ V+ +LDF ++ V ++ +SP ++ Q W
Sbjct: 2324 TIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRSPV---QTGTASPVEFLSHQAW 2380
Query: 3514 QDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLKPFELLMLLR 3573
+ LSS + F+ L DI + W+++ +S+ PE ++P ++ K + L +LR
Sbjct: 2381 GAVKVLSS--MEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNK-TALQRLCMLR 2437
Query: 3574 CFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPGSDPTADLMK 3633
R DR+ AL D++ +G +Y+ + E++ P TP+ FILSPG DP D+
Sbjct: 2438 AMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVES 2497
Query: 3634 LADRCG--FGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFLRELEKQL 3691
+ G F F +SLGQGQE A + L+ A G W+ILQN + S E + L
Sbjct: 2498 QGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNTLEMCSRETEFKSIL 2557
Query: 3692 ELMTKPHPEYRLWLTTDPTPTFPIGILQRSLKEPPNGLKLNLRNTYFKMRARALEECPHP 3751
+ H + + P G RS L +++ Y + A A + P+
Sbjct: 2558 FALCYFHA-----VVAERRKFGPQG-WNRSYPFNTGDLTISVNVLYNFLEANA--KVPYD 2609
Query: 3752 QFKKLVYVLAFFHAVVQVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAF 3811
+ Y+ ++MYGG T Y+GEF+ + + A
Sbjct: 2610 DLR---YLFG------EIMYGGHITDDWDRRLCRT----YLGEFI--RPEMLEGELSLAP 2654
Query: 3812 DYVIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSE 3871
+ +P + + Y +ID +P ++GLHPNAEIG+ +Q +++ ++ELQP+ S+
Sbjct: 2655 GFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQ 2714
Query: 3872 A--GGAMSREDFIDNIAVDVLSKLPTLYEIWRVRKQFEMNITPTLVVLLQELERFNRLIS 3929
A G +RE+ + + ++L ++ + I + + E TP +VV QE R N L
Sbjct: 2715 ARDGAGATREEKVKALLEEILERVTDEFNIPELMAKVEER-TPYIVVAFQECGRMNILTR 2773
Query: 3930 RMGSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIAR 3989
+ +L L L GE+ M + ++N+ +L+ +P+ W A + GL W + R
Sbjct: 2774 EIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNR 2833
Query: 3990 TKQYTDW-ATVEEPVVIWLSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVTSWVSAD 4048
K+ W P +WL+G P+S+L A +Q R WPLD+ +T + +
Sbjct: 2834 IKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTK-KNRE 2892
Query: 4049 EIEERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTL 4108
E P G Y+ GL++EGA WD G + + K L +P+M+I I K ++
Sbjct: 2893 EFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVY 2952
Query: 4109 RTPVYTTSQRRNAMGVGLVFESDLWTTEHCSHWILQGVCLIM 4150
PVY TSQR G V+ +L T E+ S W+L GV L++
Sbjct: 2953 SCPVYKTSQR----GPTYVWTFNLKTKENPSKWVLAGVALLL 2990
Score = 126 bits (303), Expect = 2e-27
Identities = 66/182 (36%), Positives = 101/182 (55%), Gaps = 3/182 (1%)
Query: 2497 RDPMLFGDYRNALDEEEIRYYEDLLDYEAIYFLFQEILDEYNERNAKMSIVLFEDCLEHL 2556
+ P L+ + N + E + Y + +E + E L+ +NE N M +VLFED + H+
Sbjct: 1333 QSPNLYCHFANGIGEPK---YMPVQSWELLTQTLVEALENHNEVNTVMDLVLFEDAMRHV 1389
Query: 2557 TRTHRILRMDRGNAMXXXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRM 2616
+RIL RGNA+ +LAAF + ++F+IT+ + Y FK D+ +
Sbjct: 1390 CHINRILESPRGNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASL 1449
Query: 2617 YLQLGVDNKKTVFLFTAAQILEEGFLEFINNILMIGMIPALFGDDEKDSIINSVRNDSSD 2676
L+ GV N TVFL T AQ+ +E FL IN++L G IP L+ DDE ++II++VRN+
Sbjct: 1450 CLKAGVKNLNTVFLMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKS 1509
Query: 2677 AG 2678
G
Sbjct: 1510 QG 1511
>AF327442-1|AAL37427.1| 4024|Homo sapiens ciliary dynein heavy chain 7
protein.
Length = 4024
Score = 778 bits (1925), Expect = 0.0
Identities = 507/1656 (30%), Positives = 849/1656 (51%), Gaps = 108/1656 (6%)
Query: 824 INVTDEDLQFAKSLEASWGSLYQTSLFRGNTLEQTKEKFSKLNVVEISNFLKELDDFVEK 883
+N + D++ S+ +G + + +++ E++ + + F++EL+ + ++
Sbjct: 643 VNFSPADMRLNNSVFQWYGRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQ 702
Query: 884 FDNEGPATVEDDMDRGLLLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNFNRTKAD 943
+ D+ R L + +D + + A E+ F + + + +
Sbjct: 703 SEEFYSFGDLQDVQRYLKKAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDG 762
Query: 944 YSAMDQIYKIYKAQKNAREVWAKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLM 1003
+ ++Y+ + W + + +NP + I +++ KL K S L
Sbjct: 763 LNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALA 822
Query: 1004 LDLKMKQ----FKGVVPLMVSLKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMEL 1059
+ K++ FK +PL+ + N +R RHW+ + A G S D T+ + M L
Sbjct: 823 MTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDS-TVSSFLDMNL 881
Query: 1060 HKYQDVAEEIVNHAIKELAIERGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVV 1119
Y D E I A KE ++E+ ++ + W + F + + G + L D+I +
Sbjct: 882 EPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSYRETGT---FILASVDEIQM 938
Query: 1120 KLDDDSMSLQSMAASQFIGPFLTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGGD 1179
LDD + Q+M S FI P+ ++ WE +L L+ EI++EW+ Q WLYLE IF D
Sbjct: 939 LLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSSPD 998
Query: 1180 IRTQLPEEAKKFDDIDRAFRKIMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRS 1239
I +Q+PEE ++F +D+ +R IM + +V+ TI LE L+ I++
Sbjct: 999 IMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLEL--ILKG 1056
Query: 1240 ASSDVTRKQINLSQAIAWADRASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYV 1299
+ + +K++ + ++ L ++ + + Q ++ F+ I V
Sbjct: 1057 LNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPH------LKKCFEGIAK----V 1106
Query: 1300 DHTNRPVAAKMISAEGEIMDFRNVVYT---EGRVEDWM-NLVLVEMRHTNKFITKKAIFY 1355
+ T M S+EGE+++ ++ T G+VE W+ L V + +K +T A F
Sbjct: 1107 EFTETLDITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHK-VTGDATFA 1165
Query: 1356 YGKNWKVPRTDWILEYQGMVCLAANGVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQLD 1415
Y K R +W+ ++ G L + ++WT E + I G K A++++L+ N Q+D
Sbjct: 1166 YTK---YERINWVRDWPGQTVLCVSQIFWTKEVQTA---IPMGIK-ALEQYLKTCNRQID 1218
Query: 1416 GLVVKVRQDLSSNDRLKFRTITTIDVHARDIIEGFVRDNITEAAEFEWESQLRFYWLKKD 1475
+V VR LS +R+ + +DVHARD++ V+ NI++ ++FEW SQLR+YW ++
Sbjct: 1219 DIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYW--QE 1276
Query: 1476 DNLWIRQCTGVFEYGYEYMGLNGRLVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXX 1535
++L + YGYEY+G + RLVITPLTDR Y T+ AL + L
Sbjct: 1277 NHLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTE 1336
Query: 1536 XXXDLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQ 1595
DLAKA+ CVV NC +G+D+ A+G+ GL CGAW CFDEFNRID+ VLSV++ Q
Sbjct: 1337 TTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQ 1396
Query: 1596 LQCIRSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGR 1655
+ I+ + D+L G E+ +D +FITMNPGYAGR
Sbjct: 1397 ILTIQRGI-------NAGADILMFE------------GTELKLDPTCAVFITMNPGYAGR 1437
Query: 1656 TELPESVKALFRPVVCILPDLEMICQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSH 1715
+ELP+++KALFR V ++PD MI +I L+S GF+TA+ L+ K+ Y++ EQLS Q H
Sbjct: 1438 SELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHH 1497
Query: 1716 YDWGLRALTAVLRMAGKLRRDSPGLSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFP 1775
YD+G+RA+ +VL AG L+ P +E ++L+R++ D+N PKF+ D+PLF G+ DLFP
Sbjct: 1498 YDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFP 1557
Query: 1776 GLECPRVGYPEFNAAVLEVLEKDGYVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTV 1835
G++ P+ Y + AA+ + + +K++Q+YE M+ RH M+VG GGKT
Sbjct: 1558 GVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTS 1617
Query: 1836 ILHCLVKAQTNL---GL----PTKLTVVNPKACSVIELYGILDPVTRDWTDGLYSKIFRE 1888
L A ++ GL ++TV+NPK+ ++ +LYG D V+ +W+DG+ + FR
Sbjct: 1618 AYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRA 1677
Query: 1889 MNRPAEKNERRYSLFDGDVDALWIENMNSVMDDNKLLTLANGERIRLAPYCSLLFEVGDL 1948
+ +R++ +FDG VDA+WIENMN+V+DDNK L L +GE I+++P +L+FE DL
Sbjct: 1678 F-ASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDL 1736
Query: 1949 NYASPATVSRAGMVFVDPKNLGYEPY---WERWLSTRSNEEEREQLSGLFEHYVPGAINY 2005
ASPATVSR GM++++P LG+ P W L + ++E + GLF+ VP ++ +
Sbjct: 1737 EVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEF 1796
Query: 2006 IVFGMFGLQQQTPLKTIVPQTPLNLVMQLCYMISGLLPNNED------TNMEIDKTVVEC 2059
I ++ T K + P + NLV L +I + + D N +++E
Sbjct: 1797 I-------RKHT--KELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEG 1847
Query: 2060 VFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVE--------DNPEKKATTKHFPMGF 2111
+F+ S+ S+GA+ D+ R F+ +++ + + + ++ ++K + F
Sbjct: 1848 IFLFSLIWSVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPF 1907
Query: 2112 P---TLYDYCLELTTK---LWEAWDWLVPEYEH-DRDMKFPAILVPTVDTLRLTWLIKIM 2164
P T+YDY + T+ WE W + E +D+ F I+VPT+DT+R + L++++
Sbjct: 1908 PEKGTIYDY--QFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELL 1965
Query: 2165 ESIIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPV----GKRMLVFIDDMNMPIVSH 2220
+ + F T + ++ + K+ + P + + ++ M +
Sbjct: 1966 TTHQKPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDK 2025
Query: 2221 NNQCV--PSLCSTRVQTL--LSHPLVDTYGTQQPIALLKLLFERKGFYDRGKDLNWKNLK 2276
+ V P L V + ++ P + YG Q PI LL+ + +YD KD + L
Sbjct: 2026 RRKGVFGPPLGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDL-KDCSMIKLV 2084
Query: 2277 DIGFLAAMGKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSILKGHFEI---FPEE 2333
DI + AMG GGGRN V PR++ F++ + S+ ++ I+ IL H EI FP+E
Sbjct: 2085 DIQIMCAMGPPGGGRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDE 2144
Query: 2334 IQGIVEKIVQMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMCLTHANYFSEKRTV 2393
+ +IV T+ LYK + L PTPAK HY+FNLRD SR+ G+CL+ +
Sbjct: 2145 FLDLTTQIVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVI 2204
Query: 2394 VRCWRNEFTRVICDRLINQQDNELMRGHIQEHVARY 2429
R W +E RV DRL++ D + +IQE + Y
Sbjct: 2205 KRLWVHEVLRVYYDRLLDNTDRSWLINYIQEILRNY 2240
Score = 661 bits (1633), Expect = 0.0
Identities = 364/1114 (32%), Positives = 595/1114 (53%), Gaps = 36/1114 (3%)
Query: 2683 KCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKIPEEFRPIIVEHVVHVHMSVAR 2742
+ R FP LVN TIDW WP+ AL AVA+ FL +++ + EE R ++ H S
Sbjct: 2485 RLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIE-MSEEIRDGCIDMCKSFHTSTID 2543
Query: 2743 YSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQLE 2802
S F + L+R NYVTP Y++ ++ + LL +K + ++ +R + GL K+ A+ Q+
Sbjct: 2544 LSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVA 2603
Query: 2803 DLNAKLAV---QKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAV 2859
+ +L Q + +++ E I++++ S E SK I
Sbjct: 2604 TMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKTEKIVKADETIANEQAMASKAI-- 2661
Query: 2860 EKXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVIIRGIK-- 2917
K DIT ++S +PP V++V E + I++GIK
Sbjct: 2662 -KDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKAD 2720
Query: 2918 ------------DVSWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSKKL-- 2963
+ W AK ++ D FL++L E + D I A + ++ + +
Sbjct: 2721 KIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVP 2780
Query: 2964 DTMQQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDR 3023
+ ++ S A GL K+V A+ Y A++ L +
Sbjct: 2781 EKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKE 2840
Query: 3024 LQKTLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVE 3083
+Q L L + E ++ +L+ + DL ++L A++L+ GL E+ RW+ L
Sbjct: 2841 VQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQL 2900
Query: 3084 QSRLIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVE 3143
L G+ L+++ ++Y G F+ ++RQ ++W R IP + ++ L V
Sbjct: 2901 YINLTGDILISSGVVAYLGAFTSTYRQNQT-KEWTTLCKGRDIPCSDDCSLMGTLGEAVT 2959
Query: 3144 VSGWNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQ 3203
+ WN GLP D S+ NGI+ A R+PL IDPQ+QA WIK E N+L V+ ++P
Sbjct: 2960 IRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPD 3019
Query: 3204 FLRQLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPNFRM 3263
++R LE I++G PVL ++V E +DP+++ +L K + G T + LG + ++Y P+FR
Sbjct: 3020 YVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRF 3079
Query: 3264 YLTTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSA 3323
Y+TTKL NP + P K ++N+ +T +G++DQLL +VV ER DLEE++++LI++ +
Sbjct: 3080 YITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAE 3139
Query: 3324 NKSLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKL 3383
NK L +ED +L L++S GN+L++ + L ++K+ A E+ +K E+AE T K I+
Sbjct: 3140 NKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALANEISQKQEVAEETEKKIDTT 3199
Query: 3384 RDGYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNII 3443
R GYRP+A SILFF L+D+A + MYQYSL+ ++++F S+ + + IL KRL+ +
Sbjct: 3200 RMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFINLFILSIENSEKSEILAKRLQILK 3259
Query: 3444 DMLTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLEKSARSS 3503
D T ++Y C +FE+ KLLFSF + I L E +++A+ F + G + L+ + ++
Sbjct: 3260 DHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKAEWRFLLTGGIGLD-NPYAN 3318
Query: 3504 PAPWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKL 3563
P W+P + W +I +L D P F T+ + + + W++ +DS P P + +K
Sbjct: 3319 PCTWLPQKSWDEICRL-DDLP-AFKTIRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDKA 3376
Query: 3564 KPFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSP 3623
F+ ++++RC R D++ L ++I +G +I PP L + P++F+LSP
Sbjct: 3377 NEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSP 3436
Query: 3624 GSDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSF 3683
G+DP A L+K AD G+GG K LSLGQGQ A+ +LE A+ G W++LQNCHL S+
Sbjct: 3437 GADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSW 3496
Query: 3684 LRELEKQLELMT--KPHPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLNLRNTYF 3738
+ LEK E ++ HP++R+WLT+ P+P FP+ +LQ +K E P GL+ N+ +Y
Sbjct: 3497 MPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRSYL 3556
Query: 3739 KMRARALE---ECPHP-QFKKLVYVLAFFHAVVQ 3768
E C P +FKKL+Y L FFHA+VQ
Sbjct: 3557 MDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQ 3590
Score = 190 bits (463), Expect = 9e-47
Identities = 107/352 (30%), Positives = 186/352 (52%), Gaps = 14/352 (3%)
Query: 3808 DYAFD----YVIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLI 3863
DY FD Y +PP G+ YI++ TLPL PE+FG++ NA+I + ++ +++
Sbjct: 3672 DYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNIL 3731
Query: 3864 ELQPQTSEAGGAMSREDFIDNIAVDVLSKLPTLYEIWRVRKQFEMNITPTL-VVLLQELE 3922
Q +++ AG A S ++ ++ +A D+L KLP ++I +++ T ++ VL+QE+
Sbjct: 3732 LTQSRSAGAG-AKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQSMNTVLVQEMG 3790
Query: 3923 RFNRLISRMGSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGW 3982
RFN+L+ + + ++KA+ G M L+ V S+ N ++P++W + + K LG +
Sbjct: 3791 RFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSY 3850
Query: 3983 MDHFIARTKQYTDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVT 4042
++ F+AR K W V P V WLSG +++L Q R YT P+D +V
Sbjct: 3851 VNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEV- 3909
Query: 4043 SWVSADEIEERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKL 4102
+ E + P G ++ GL+L+GA W+ L SHPK+L +P+M++ P + +
Sbjct: 3910 --MEDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADI 3967
Query: 4103 KLQNTLRTPVYTTSQRRNAM-----GVGLVFESDLWTTEHCSHWILQGVCLI 4149
+ + P+Y TS+RR + V L + + HWI +GV L+
Sbjct: 3968 PKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALL 4019
Score = 99.1 bits (236), Expect = 3e-19
Identities = 54/173 (31%), Positives = 94/173 (54%), Gaps = 3/173 (1%)
Query: 2500 MLFGDYRNALDEEEIRYYEDLLDYEAIYFLFQEILDEYNERNAK-MSIVLFEDCLEHLTR 2558
++F D+ + E+ Y ++ D + + + + L+EYN + K M++VLF +EH++R
Sbjct: 2268 LMFCDFHDPKREDT--NYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISR 2325
Query: 2559 THRILRMDRGNAMXXXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMYL 2618
RIL+ R +A+ +LAA A +F++ +++ Y+ + +D+K +
Sbjct: 2326 ISRILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILR 2385
Query: 2619 QLGVDNKKTVFLFTAAQILEEGFLEFINNILMIGMIPALFGDDEKDSIINSVR 2671
+ + VFLFT QI EE FLE ++N+L G IP LF DEK I + +R
Sbjct: 2386 KCAEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMR 2438
>AB023161-1|BAA76788.2| 4031|Homo sapiens KIAA0944 protein protein.
Length = 4031
Score = 776 bits (1920), Expect = 0.0
Identities = 506/1656 (30%), Positives = 848/1656 (51%), Gaps = 108/1656 (6%)
Query: 824 INVTDEDLQFAKSLEASWGSLYQTSLFRGNTLEQTKEKFSKLNVVEISNFLKELDDFVEK 883
+N + D++ S+ +G + + +++ E++ + + F++EL+ + ++
Sbjct: 650 VNFSPADMRLNNSVFQWYGRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQ 709
Query: 884 FDNEGPATVEDDMDRGLLLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNFNRTKAD 943
+ D+ R L + +D + + A E+ F + + + +
Sbjct: 710 SEEFYSFGDLQDVQRYLKKAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDG 769
Query: 944 YSAMDQIYKIYKAQKNAREVWAKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLM 1003
+ ++Y+ + W + + +NP + I +++ KL K S L
Sbjct: 770 LNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALA 829
Query: 1004 LDLKMKQ----FKGVVPLMVSLKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMEL 1059
+ K++ FK +PL+ + N +R RHW+ + A G S D T+ + M L
Sbjct: 830 MTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDS-TVSSFLDMNL 888
Query: 1060 HKYQDVAEEIVNHAIKELAIERGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVV 1119
Y D E I A KE ++E+ ++ + W + F + + G + L D+I +
Sbjct: 889 EPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSYRETGT---FILASVDEIQM 945
Query: 1120 KLDDDSMSLQSMAASQFIGPFLTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGGD 1179
LDD + Q+M S FI P+ ++ WE +L L+ EI++EW+ Q WLYLE IF D
Sbjct: 946 LLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSSPD 1005
Query: 1180 IRTQLPEEAKKFDDIDRAFRKIMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRS 1239
I +Q+PEE ++F +D+ +R M + +V+ TI LE L+ I++
Sbjct: 1006 IMSQMPEEGRRFTAVDKTWRDTMRSVMQDKHVLTVVTIDRMLERLKKSNELLEL--ILKG 1063
Query: 1240 ASSDVTRKQINLSQAIAWADRASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYV 1299
+ + +K++ + ++ L ++ + + Q ++ F+ I V
Sbjct: 1064 LNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPH------LKKCFEGIAK----V 1113
Query: 1300 DHTNRPVAAKMISAEGEIMDFRNVVYT---EGRVEDWM-NLVLVEMRHTNKFITKKAIFY 1355
+ T M S+EGE+++ ++ T G+VE W+ L V + +K +T A F
Sbjct: 1114 EFTETLDITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHK-VTGDATFA 1172
Query: 1356 YGKNWKVPRTDWILEYQGMVCLAANGVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQLD 1415
Y K R +W+ ++ G L + ++WT E + I G K A++++L+ N Q+D
Sbjct: 1173 YTK---YERINWVRDWPGQTVLCVSQIFWTKEVQTA---IPMGIK-ALEQYLKTCNRQID 1225
Query: 1416 GLVVKVRQDLSSNDRLKFRTITTIDVHARDIIEGFVRDNITEAAEFEWESQLRFYWLKKD 1475
+V VR LS +R+ + +DVHARD++ V+ NI++ ++FEW SQLR+YW ++
Sbjct: 1226 DIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYW--QE 1283
Query: 1476 DNLWIRQCTGVFEYGYEYMGLNGRLVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXX 1535
++L + YGYEY+G + RLVITPLTDR Y T+ AL + L
Sbjct: 1284 NHLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTE 1343
Query: 1536 XXXDLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQ 1595
DLAKA+ CVV NC +G+D+ A+G+ GL CGAW CFDEFNRID+ VLSV++ Q
Sbjct: 1344 TTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQ 1403
Query: 1596 LQCIRSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGR 1655
+ I+ + D+L G E+ +D +FITMNPGYAGR
Sbjct: 1404 ILTIQRGI-------NAGADILMFE------------GTELKLDPTCAVFITMNPGYAGR 1444
Query: 1656 TELPESVKALFRPVVCILPDLEMICQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSH 1715
+ELP+++KALFR V ++PD MI +I L+S GF+TA+ L+ K+ Y++ EQLS Q H
Sbjct: 1445 SELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHH 1504
Query: 1716 YDWGLRALTAVLRMAGKLRRDSPGLSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFP 1775
YD+G+RA+ +VL AG L+ P +E ++L+R++ D+N PKF+ D+PLF G+ DLFP
Sbjct: 1505 YDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFP 1564
Query: 1776 GLECPRVGYPEFNAAVLEVLEKDGYVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTV 1835
G++ P+ Y + AA+ + + +K++Q+YE M+ RH M+VG GGKT
Sbjct: 1565 GVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTS 1624
Query: 1836 ILHCLVKAQTNL---GL----PTKLTVVNPKACSVIELYGILDPVTRDWTDGLYSKIFRE 1888
L A ++ GL ++TV+NPK+ ++ +LYG D V+ +W+DG+ + FR
Sbjct: 1625 AYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRA 1684
Query: 1889 MNRPAEKNERRYSLFDGDVDALWIENMNSVMDDNKLLTLANGERIRLAPYCSLLFEVGDL 1948
+ +R++ +FDG VDA+WIENMN+V+DDNK L L +GE I+++P +L+FE DL
Sbjct: 1685 F-ASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDL 1743
Query: 1949 NYASPATVSRAGMVFVDPKNLGYEPY---WERWLSTRSNEEEREQLSGLFEHYVPGAINY 2005
ASPATVSR GM++++P LG+ P W L + ++E + GLF+ VP ++ +
Sbjct: 1744 EVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEF 1803
Query: 2006 IVFGMFGLQQQTPLKTIVPQTPLNLVMQLCYMISGLLPNNED------TNMEIDKTVVEC 2059
I ++ T K + P + NLV L +I + + D N +++E
Sbjct: 1804 I-------RKHT--KELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLEG 1854
Query: 2060 VFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVE--------DNPEKKATTKHFPMGF 2111
+F+ S+ S+GA+ D+ R F+ +++ + + + ++ ++K + F
Sbjct: 1855 IFLFSLIWSVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPF 1914
Query: 2112 P---TLYDYCLELTTK---LWEAWDWLVPEYEH-DRDMKFPAILVPTVDTLRLTWLIKIM 2164
P T+YDY + T+ WE W + E +D+ F I+VPT+DT+R + L++++
Sbjct: 1915 PEKGTIYDY--QFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELL 1972
Query: 2165 ESIIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPV----GKRMLVFIDDMNMPIVSH 2220
+ + F T + ++ + K+ + P + + ++ M +
Sbjct: 1973 TTHQKPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDK 2032
Query: 2221 NNQCV--PSLCSTRVQTL--LSHPLVDTYGTQQPIALLKLLFERKGFYDRGKDLNWKNLK 2276
+ V P L V + ++ P + YG Q PI LL+ + +YD KD + L
Sbjct: 2033 RRKGVFGPPLGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDL-KDCSMIKLV 2091
Query: 2277 DIGFLAAMGKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSILKGHFEI---FPEE 2333
DI + AMG GGGRN V PR++ F++ + S+ ++ I+ IL H EI FP+E
Sbjct: 2092 DIQIMCAMGPPGGGRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDE 2151
Query: 2334 IQGIVEKIVQMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMCLTHANYFSEKRTV 2393
+ +IV T+ LYK + L PTPAK HY+FNLRD SR+ G+CL+ +
Sbjct: 2152 FLDLTTQIVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVI 2211
Query: 2394 VRCWRNEFTRVICDRLINQQDNELMRGHIQEHVARY 2429
R W +E RV DRL++ D + +IQE + Y
Sbjct: 2212 KRLWVHEVLRVYYDRLLDNTDRSWLINYIQEILRNY 2247
Score = 661 bits (1633), Expect = 0.0
Identities = 364/1114 (32%), Positives = 595/1114 (53%), Gaps = 36/1114 (3%)
Query: 2683 KCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKIPEEFRPIIVEHVVHVHMSVAR 2742
+ R FP LVN TIDW WP+ AL AVA+ FL +++ + EE R ++ H S
Sbjct: 2492 RLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIE-MSEEIRDGCIDMCKSFHTSTID 2550
Query: 2743 YSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQLE 2802
S F + L+R NYVTP Y++ ++ + LL +K + ++ +R + GL K+ A+ Q+
Sbjct: 2551 LSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVA 2610
Query: 2803 DLNAKLAV---QKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAV 2859
+ +L Q + +++ E I++++ S E SK I
Sbjct: 2611 TMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKTEKIVKADETIANEQAMASKAI-- 2668
Query: 2860 EKXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVIIRGIK-- 2917
K DIT ++S +PP V++V E + I++GIK
Sbjct: 2669 -KDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKAD 2727
Query: 2918 ------------DVSWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSKKL-- 2963
+ W AK ++ D FL++L E + D I A + ++ + +
Sbjct: 2728 KIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVP 2787
Query: 2964 DTMQQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDR 3023
+ ++ S A GL K+V A+ Y A++ L +
Sbjct: 2788 EKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKE 2847
Query: 3024 LQKTLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVE 3083
+Q L L + E ++ +L+ + DL ++L A++L+ GL E+ RW+ L
Sbjct: 2848 VQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQL 2907
Query: 3084 QSRLIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVE 3143
L G+ L+++ ++Y G F+ ++RQ ++W R IP + ++ L V
Sbjct: 2908 YINLTGDILISSGVVAYLGAFTSTYRQNQT-KEWTTLCKGRDIPCSDDCSLMGTLGEAVT 2966
Query: 3144 VSGWNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQ 3203
+ WN GLP D S+ NGI+ A R+PL IDPQ+QA WIK E N+L V+ ++P
Sbjct: 2967 IRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPD 3026
Query: 3204 FLRQLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPNFRM 3263
++R LE I++G PVL ++V E +DP+++ +L K + G T + LG + ++Y P+FR
Sbjct: 3027 YVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRF 3086
Query: 3264 YLTTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSA 3323
Y+TTKL NP + P K ++N+ +T +G++DQLL +VV ER DLEE++++LI++ +
Sbjct: 3087 YITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAE 3146
Query: 3324 NKSLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKL 3383
NK L +ED +L L++S GN+L++ + L ++K+ A E+ +K E+AE T K I+
Sbjct: 3147 NKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALANEISQKQEVAEETEKKIDTT 3206
Query: 3384 RDGYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNII 3443
R GYRP+A SILFF L+D+A + MYQYSL+ ++++F S+ + + IL KRL+ +
Sbjct: 3207 RMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFINLFILSIENSEKSEILAKRLQILK 3266
Query: 3444 DMLTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLEKSARSS 3503
D T ++Y C +FE+ KLLFSF + I L E +++A+ F + G + L+ + ++
Sbjct: 3267 DHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKAEWRFLLTGGIGLD-NPYAN 3325
Query: 3504 PAPWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKL 3563
P W+P + W +I +L D P F T+ + + + W++ +DS P P + +K
Sbjct: 3326 PCTWLPQKSWDEICRL-DDLP-AFKTIRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDKA 3383
Query: 3564 KPFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSP 3623
F+ ++++RC R D++ L ++I +G +I PP L + P++F+LSP
Sbjct: 3384 NEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSP 3443
Query: 3624 GSDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSF 3683
G+DP A L+K AD G+GG K LSLGQGQ A+ +LE A+ G W++LQNCHL S+
Sbjct: 3444 GADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSW 3503
Query: 3684 LRELEKQLELMT--KPHPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLNLRNTYF 3738
+ LEK E ++ HP++R+WLT+ P+P FP+ +LQ +K E P GL+ N+ +Y
Sbjct: 3504 MPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRSYL 3563
Query: 3739 KMRARALE---ECPHP-QFKKLVYVLAFFHAVVQ 3768
E C P +FKKL+Y L FFHA+VQ
Sbjct: 3564 MDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQ 3597
Score = 190 bits (463), Expect = 9e-47
Identities = 107/352 (30%), Positives = 186/352 (52%), Gaps = 14/352 (3%)
Query: 3808 DYAFD----YVIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLI 3863
DY FD Y +PP G+ YI++ TLPL PE+FG++ NA+I + ++ +++
Sbjct: 3679 DYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNIL 3738
Query: 3864 ELQPQTSEAGGAMSREDFIDNIAVDVLSKLPTLYEIWRVRKQFEMNITPTL-VVLLQELE 3922
Q +++ AG A S ++ ++ +A D+L KLP ++I +++ T ++ VL+QE+
Sbjct: 3739 LTQSRSAGAG-AKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQSMNTVLVQEMG 3797
Query: 3923 RFNRLISRMGSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGW 3982
RFN+L+ + + ++KA+ G M L+ V S+ N ++P++W + + K LG +
Sbjct: 3798 RFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSY 3857
Query: 3983 MDHFIARTKQYTDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVT 4042
++ F+AR K W V P V WLSG +++L Q R YT P+D +V
Sbjct: 3858 VNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEV- 3916
Query: 4043 SWVSADEIEERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKL 4102
+ E + P G ++ GL+L+GA W+ L SHPK+L +P+M++ P + +
Sbjct: 3917 --MEDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADI 3974
Query: 4103 KLQNTLRTPVYTTSQRRNAM-----GVGLVFESDLWTTEHCSHWILQGVCLI 4149
+ + P+Y TS+RR + V L + + HWI +GV L+
Sbjct: 3975 PKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALL 4026
Score = 99.1 bits (236), Expect = 3e-19
Identities = 54/173 (31%), Positives = 94/173 (54%), Gaps = 3/173 (1%)
Query: 2500 MLFGDYRNALDEEEIRYYEDLLDYEAIYFLFQEILDEYNERNAK-MSIVLFEDCLEHLTR 2558
++F D+ + E+ Y ++ D + + + + L+EYN + K M++VLF +EH++R
Sbjct: 2275 LMFCDFHDPKREDT--NYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISR 2332
Query: 2559 THRILRMDRGNAMXXXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMYL 2618
RIL+ R +A+ +LAA A +F++ +++ Y+ + +D+K +
Sbjct: 2333 ISRILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILR 2392
Query: 2619 QLGVDNKKTVFLFTAAQILEEGFLEFINNILMIGMIPALFGDDEKDSIINSVR 2671
+ + VFLFT QI EE FLE ++N+L G IP LF DEK I + +R
Sbjct: 2393 KCAEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMR 2445
>AK125796-1|BAC86296.1| 617|Homo sapiens protein ( Homo sapiens cDNA
FLJ43808 fis, clone TESTI4001148, weakly similar to
Dynein beta chain, ciliary. ).
Length = 617
Score = 727 bits (1796), Expect = 0.0
Identities = 377/650 (58%), Positives = 462/650 (71%), Gaps = 38/650 (5%)
Query: 1202 MLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASSDVTRKQINLSQAIAWADRA 1261
M +T K + CC RL + N+ GL+ K +S + + K+ + +D
Sbjct: 1 MGETLKDPVIKRCCEAPNRLSDLQNVSEGLE--KCQKSLNDYLDSKRNAFPRFFFISDDE 58
Query: 1262 SLSLVPRSHLHAKAQAKRDTFSCVQP----MFDNIRALDLYVDHTNRPVAAKMISAEGEI 1317
LS++ S D CVQ M+DNI +L + + + MISAEGE+
Sbjct: 59 LLSILGSS----------DPL-CVQEHMIKMYDNIASLRFNDGDSGEKLVSAMISAEGEV 107
Query: 1318 MDFRNVVYTEGRVEDWMNLVLVEMRHTNKFITKKAIFYYGKNWKVPRTDWILEYQGMVCL 1377
M+FR +V EGRVEDWM VL EMR TN+ ITK+AIF Y ++ R DW+L YQGMV L
Sbjct: 108 MEFRKIVRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRS--RVDWMLLYQGMVVL 165
Query: 1378 AANGVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQLDGLVVKVRQDLSSNDRLKFRTIT 1437
AA+ VWWT E E+ F + +KG K+AMK + ++ + Q+D LV ++ LS NDR K+ T+
Sbjct: 166 AASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDRKKYNTVL 225
Query: 1438 TIDVHARDIIEGFVRDNITEAAEFEWESQLRFYWLKKDDNLWIRQCTGVFEYGYEYMGLN 1497
IDVHARDI++ F+R +I EA EF+WESQLRFYW ++ D L IRQCTG F YGYEYMGLN
Sbjct: 226 IIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYGYEYMGLN 285
Query: 1498 GRLVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGM 1557
GRLVITPLTDRIYLT+TQAL+M L DLAKALGLLCVVTNCGEGM
Sbjct: 286 GRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGM 345
Query: 1558 DFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLKRFTVNTDVL 1617
D+RAVG+I +GL QCGAWGCFDEFNRID SVLSVIS+Q+Q IR+AL+ +L F
Sbjct: 346 DYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTFQFE---- 401
Query: 1618 KPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTELPESVKALFRPVVCILPDLE 1677
GQEI++DS++GIFITMNPGYAGRTELPESVKALFRPVV I+PDL+
Sbjct: 402 ---------------GQEISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQ 446
Query: 1678 MICQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTAVLRMAGKLRRDS 1737
IC+I LFS+GFL AK LAKKMTVLYK+AREQLSKQ HYD+GLRAL +VL MAG+L+R S
Sbjct: 447 QICEIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGS 506
Query: 1738 PGLSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEK 1797
L E +VLMRALRDMN PKFV EDVPLFLGLI DLFPGL+CPRV YP+FN AV +VLE+
Sbjct: 507 SDLREDVVLMRALRDMNLPKFVLEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEE 566
Query: 1798 DGYVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNL 1847
+GY VLP QVDKVVQ++ETM+TRH TM+VGPT GGK+V+++ L +AQTNL
Sbjct: 567 NGYAVLPIQVDKVVQMFETMLTRHTTMVVGPTRGGKSVVINTLCQAQTNL 616
>AF494040-1|AAM12861.1| 4116|Homo sapiens axonemal heavy chain dynein
type 3 protein.
Length = 4116
Score = 726 bits (1795), Expect = 0.0
Identities = 482/1596 (30%), Positives = 804/1596 (50%), Gaps = 109/1596 (6%)
Query: 881 VEKFDNEGPATVEDDMDRGLLLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNFNRT 940
+E F T E+ M + + E K ++ + +++ E+L + + +
Sbjct: 804 LESFRKREVMTTEE-MKHNVEKLNELSKNLNRAFAEFELINKEEELLEKEKSTYPLLQAM 862
Query: 941 KADYSAMDQIYKIYKAQKNAREVWAKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRLSST 1000
+ +Q++ E W LN + + + I ++ KL K +
Sbjct: 863 LKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQIAEEIGNMWRTTYKLIKTLSDVPA 922
Query: 1001 GLML----DLKMKQFKGVVPLMVSLKNEAMRERHWKELMAKTGQDFDMSPDRFT-LENMF 1055
L +K+ +FK +P++ N M++RHW+++ G +++ P T L NM
Sbjct: 923 PRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQQISEIVG--YEIKPTETTCLSNML 980
Query: 1056 AMELHKYQDVAEEIVNHAIKELAIERGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCD 1115
K+ + E I A KE ++E+ + ++ W N++FS ++ R D L D
Sbjct: 981 EFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNVTFSFVKY--RDTDTNI-LCAID 1037
Query: 1116 DIVVKLDDDSMSLQSMAASQFIGPFLTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIF 1175
DI + LDD + Q+M S FI P + WE +L I + ++ W+ Q WLYLE IF
Sbjct: 1038 DIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQDNLDAWLKCQATWLYLEPIF 1097
Query: 1176 VGGDIRTQLPEEAKKFDDIDRAFRKIMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSK 1235
DI Q+PEE +KF +D ++ +M K ++ E+ L+
Sbjct: 1098 SSEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAADQPRMAEKLQEANFLLED-- 1155
Query: 1236 IIRSASSDVTRKQINLSQAIAWADRASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRAL 1295
I + + + +K++ + ++ L ++ + + Q ++ F+ I L
Sbjct: 1156 IQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPH------LKKCFEGIAKL 1209
Query: 1296 DLYVDHTNRPVAAKMISAEGEIMDFRNVVY---TEGRVEDWMNLVLVEMRHTNKFITKKA 1352
+ T+ MIS+E E + F +Y +G VE W+ V M + + +
Sbjct: 1210 EF----TDNLEIVGMISSEKETVPFIQKIYPANAKGMVEKWLQQVEQMMLASMREVIGLG 1265
Query: 1353 IFYYGKNWKVPRTDWILEYQGMVCLAANGVWWTAETEETFLRIKKGNKRAMKEHLQQQNE 1412
I Y K VPR W+L++ G V + + ++WT E + + + + L++ N+
Sbjct: 1266 IEAYVK---VPRNHWVLQWPGQVVICVSSIFWTQEVSQALA------ENTLLDFLKKSND 1316
Query: 1413 QLDGLVVKVRQDLSSNDRLKFRTITTIDVHARDIIEGFVRDNITEAAEFEWESQLRFYWL 1472
Q+ +V VR LSS RL +T IDVHARD++ D +++ +F+W SQLR+YW+
Sbjct: 1317 QIAQIVQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDFQWISQLRYYWV 1376
Query: 1473 KKDDNLWIRQCTGVFEYGYEYMGLNGRLVITPLTDRIYLTITQALTMQLXXXXXXXXXXX 1532
KD + I + YGYEY+G + RLVITPLTDR Y T+ AL + L
Sbjct: 1377 AKDVQVQIITTEAL--YGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTG 1434
Query: 1533 XXXXXXDLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVI 1592
DLAKAL CVV NC +G+D++A+G+ GL Q GAW CFDEFNRI++ VLSV+
Sbjct: 1435 KTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVV 1494
Query: 1593 STQLQCIRSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGY 1652
+ Q+ I+ A++ KLK F G E++++ +FITMNPGY
Sbjct: 1495 AQQILSIQQAIIRKLKTFIFE-------------------GTELSLNPTCAVFITMNPGY 1535
Query: 1653 AGRTELPESVKALFRPVVCILPDLEMICQISLFSDGFLTAKVLAKKMTVLYKVAREQLSK 1712
AGR ELP+++KALFR V ++PD +I +ISL+S GFL ++ LA+K+ Y++ EQLS
Sbjct: 1536 AGRAELPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSS 1595
Query: 1713 QSHYDWGLRALTAVLRMAGKLRRDSPGLSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKD 1772
Q HYD+G+RA+ +VL AG L+ P +E ++L+RAL D+N KF+ +DVPLF G+I D
Sbjct: 1596 QHHYDYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQDVPLFQGIISD 1655
Query: 1773 LFPGLECPRVGYPEFNAAVLEVLEKDGYVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGG 1832
LFPG+ P+ Y F + + ++K +P + K++Q+YE M+ RH M+VG GG
Sbjct: 1656 LFPGVVLPKPDYEVFLKVLNDNIKKMKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGG 1715
Query: 1833 KTVILHCLVKAQTNLGLPTKL-------TVVNPKACSVIELYGILDPVTRDWTDGLYSKI 1885
KT L A +L ++ ++NPKA ++ +LYG D V+ +W DG+ +
Sbjct: 1716 KTSAYKVLAAALGDLHAANQMEEFAVEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANA 1775
Query: 1886 FREMNRPAEKNERRYSLFDGDVDALWIENMNSVMDDNKLLTLANGERIRLAPYCSLLFEV 1945
FRE + ++R++ +FDG VDA+WIENMN+V+DDNK L L +GE I++ SL+FE
Sbjct: 1776 FRE-QASSLSDDRKWIIFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEP 1834
Query: 1946 GDLNYASPATVSRAGMVFVDPKNLGYEPYWERWLSTRSN---EEEREQLSGLFEHYVPGA 2002
DL ASPATVSR GM++++P LG++P + ++ T + +E +E ++ +F V
Sbjct: 1835 ADLEQASPATVSRCGMIYMEPHQLGWKPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPC 1894
Query: 2003 INYIVFGMFGLQQQTPLKTIVPQTPLNLVMQLCYMISGLLPN---NEDTNMEIDKTV--- 2056
+ FG + K +V +P++L + + S LL E+ ME+ + +
Sbjct: 1895 LE---FG------RLHCKFVVQTSPIHLAFSMMRLYSSLLDEIRAVEEEEMELGEGLSSQ 1945
Query: 2057 -----VECVFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVEDN---PEKKATTKH-- 2106
++ +F+ S+ ++ I + R FD + + +M ++DN P+ TK+
Sbjct: 1946 QIFLWLQGLFLFSLVWTVAGTINADSRKKFDVFFRNL--IMGMDDNHPRPKSVKLTKNNI 2003
Query: 2107 FPMGFPTLYD-YCLELTTKLWEAWDWLVPEYEH--DRDMKFPAILVPTVDTLRLTWLIKI 2163
FP ++YD Y ++ + WE W + + E K +++PT++T R ++ +K
Sbjct: 2004 FPER-GSIYDFYFIKQASGHWETWTQYITKEEEKVPAGAKVSELIIPTMETARQSFFLKT 2062
Query: 2164 MESIIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPV----GKRMLVFIDDMNMPIVS 2219
M F T + + + K+T+ P + D+ M +
Sbjct: 2063 YLDHEIPMLFVGPTGT-GKSAITNNFLLHLPKNTYLPNCINFSARTSANQTQDIIMSKLD 2121
Query: 2220 HNNQCV--PSLCSTRVQTL--LSHPLVDTYGTQQPIALLKLLFERKGFYDRGKDLNWKNL 2275
+ + P + V + L+ P + YG Q PI LL+ + ++D+ KD ++
Sbjct: 2122 RRRKGLFGPPIGKKAVVFVDDLNMPAKEVYGAQPPIELLRQWIDHGYWFDK-KDTTRLDI 2180
Query: 2276 KDIGFLAAMGKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSILKGHF-EIFPEEI 2334
D+ + AMG GGGRND+ RF ++ ++ ++ L I+ SI+ HF + F
Sbjct: 2181 VDMLLVTAMGPPGGGRNDITGRFTRHLNIISINAFEDDILTKIFSSIVDWHFGKGFDVMF 2240
Query: 2335 QGIVEKIVQMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMCLTHANYFSEKRTVV 2394
+ +VQ T +Y+ + PTP+K HY+FNLRD SR+ G+ L + + +
Sbjct: 2241 LRYGKMLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKCI 2300
Query: 2395 RCWRNEFTRVICDRLINQQDNELMRGHIQEHVARYF 2430
R W +E RV DRLI+++D ++ ++E + F
Sbjct: 2301 RLWIHEVYRVFYDRLIDKEDRQVFFNMVKETTSNCF 2336
Score = 593 bits (1464), Expect = e-168
Identities = 340/1114 (30%), Positives = 578/1114 (51%), Gaps = 35/1114 (3%)
Query: 2683 KCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKIPEEFRPIIVEHVVHVHMSVAR 2742
+ R FP L+N TIDW WP AL VAN FL DV+ + + R +V + SV +
Sbjct: 2576 RLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDVE-LDDNIRVEVVSMCKYFQESVKK 2634
Query: 2743 YSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQLE 2802
S ++ +LRR+NYVTP Y++ + + LLN K + R GL K+ A Q+
Sbjct: 2635 LSLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFAASQVA 2694
Query: 2803 DLNAKL-AVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVEK 2861
+ +L A+Q ++ + ++++K I T E + + K
Sbjct: 2695 VMQRELTALQPQLILTSEETAKMMVK-IEAETREADGKKLLVQADEKEANVAAAIAQGIK 2753
Query: 2862 XXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVIIRGIK---- 2917
DI+ ++S PP V++V E + I++G+K
Sbjct: 2754 NECEGDLAEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVMESICIMKGMKPERK 2813
Query: 2918 -DVS---------WKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSKKLD--T 2965
D S W +K ++ D FL +L+ + D I +K ++ +
Sbjct: 2814 PDPSGSGKMIEDYWGVSKKILGDLKFLESLKTYDKDNIPPLTMKRIRERFINHPEFQPAV 2873
Query: 2966 MQQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQ 3025
++ +S A GL K+V A+ Y + + L E+ +
Sbjct: 2874 IKNVSSACEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLAAQMQKLNQKRAELKLVV 2933
Query: 3026 KTLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQS 3085
L LN+ +E ++++L+E ++ ++LV A+KL+SGL E+ RWTE L + +
Sbjct: 2934 DRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRYT 2993
Query: 3086 RLIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVS 3145
L G+ LL++ ++Y G F+ +R WL + ++ IP F++ L + +++
Sbjct: 2994 NLTGDVLLSSGTVAYLGAFTVDYR-VQCQNQWLAECKDKVIPGFSDFSLSHTLGDPIKIR 3052
Query: 3146 GWNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFL 3205
W GLP D S+ NGI+ + + R+ L IDP QA WIK E N L V+ F+D ++
Sbjct: 3053 AWQIAGLPVDSFSIDNGIIVSNSRRWALMIDPHGQANKWIKNMEKANKLAVIKFSDSNYM 3112
Query: 3206 RQLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPNFRMYL 3265
R LE A++ G PVL +++ E +D ++ +L K + G ++ LG ++Y +F++Y+
Sbjct: 3113 RMLENALQLGTPVLIENIGEELDASIEPILLKATFKQQGVEYMRLGENIIEYSRDFKLYI 3172
Query: 3266 TTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANK 3325
TT+L NP + P K ++N+ +T GL+DQLL +V E+ +LEE++ LI+E++ NK
Sbjct: 3173 TTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKEKPELEEKKNQLIVESAKNK 3232
Query: 3326 SLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRD 3385
L +ED +L L+ S GN+L++ + L ++K + E+ EK ++A T I++ R
Sbjct: 3233 KHLKEIEDKILEVLSMSKGNILEDETAIKVLSSSKVLSEEISEKQKVASMTETQIDETRM 3292
Query: 3386 GYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDM 3445
GY+PVA + +FF +SD+A + MYQYSL+ +++++ SL + + L R+K IID
Sbjct: 3293 GYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINLYMHSLTHSTKSEELNLRIKYIIDH 3352
Query: 3446 LTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLEKSARSSPA 3505
T ++Y+ C +FE+ KLLFS + I + + + +++ F + G ++L+ + +PA
Sbjct: 3353 FTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVWYFLLTGGIALD-NPYPNPA 3411
Query: 3506 P-WMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLK 3564
P W+ + W +I++ S+ P L + + + L EW+ +DS P ++P +++ +
Sbjct: 3412 PQWLSEKAWAEIVRASA-LP-KLHGLMEHLEQNLGEWKLIYDSAWPHEEQLPGSWKFS-Q 3468
Query: 3565 PFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPG 3624
E +++LRC R D++ A+ ++I MG+ YI P L ++ P++F+LSP
Sbjct: 3469 GLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYNDSSCCAPLIFVLSPS 3528
Query: 3625 SDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFL 3684
+DP A L+K AD G GG + + +SLGQGQ A ++ AI G W++LQNCHL S++
Sbjct: 3529 ADPMAGLLKFADDLGMGGTRTQTISLGQGQGPIAAKMINNAIKDGTWVVLQNCHLAASWM 3588
Query: 3685 RELEKQLELMTKP---HPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLNLRNTYF 3738
LEK E + P + +RLWLT+ P+ FP+ ILQ +K EPP GL+ NL +Y
Sbjct: 3589 PTLEKICEEVIVPESTNARFRLWLTSYPSEKFPVSILQNGIKMTNEPPKGLRANLLRSYL 3648
Query: 3739 K---MRARALEECPHP-QFKKLVYVLAFFHAVVQ 3768
+ C ++K+++ L FFHAVVQ
Sbjct: 3649 NDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQ 3682
Score = 200 bits (487), Expect = 1e-49
Identities = 118/347 (34%), Positives = 182/347 (52%), Gaps = 9/347 (2%)
Query: 3813 YVIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEA 3872
Y IPP G YID++ LP+ PEVFGLH NA+I +Q +++ ++ P+ S
Sbjct: 3772 YYIPPHGSYQSYIDYLRNLPITAHPEVFGLHENADITKDNQETNQLFEGVLLTLPRQS-G 3830
Query: 3873 GGAMSREDFIDNIAVDVLSKLPTLYEIWRVRKQFEMNITPTL-VVLLQELERFNRLISRM 3931
G S ++ ++ +A D+LSKLP +++ V K + + ++ VL QEL RFNRL +
Sbjct: 3831 GSGKSPQEVVEELAQDILSKLPRDFDLEEVMKLYPVVYEESMNTVLRQELIRFNRLTKVV 3890
Query: 3932 GSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTK 3991
+L L +A+ G++ M + L+ V S+ G++P +W A + + K LGG++ +AR
Sbjct: 3891 RRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARLT 3950
Query: 3992 QYTDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVTSWVSADEIE 4051
+ +W PVV W+SG + +S+L Q R YT P+D +VT + +E
Sbjct: 3951 FFQEWIDKGPPVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFEVTPQETV--ME 4008
Query: 4052 ERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRTP 4111
P G Y++GL+LEGARWD + S PK+L LPI+++ P E Q+ P
Sbjct: 4009 NNPEDGAYIKGLFLEGARWDRKTMQIGESLPKILYDPLPIIWLKPGESAMFLHQDIYVCP 4068
Query: 4112 VYTTSQRRNAM-----GVGLVFESDLWTTEHCSHWILQGVCLIMNTD 4153
VY TS RR + V +L T HWI +GV + D
Sbjct: 4069 VYKTSARRGTLSTTGHSTNYVLSIELPTDMPQKHWINRGVASLCQLD 4115
Score = 122 bits (293), Expect = 4e-26
Identities = 59/180 (32%), Positives = 104/180 (57%), Gaps = 3/180 (1%)
Query: 2500 MLFGDYRNALDEEEIRYYEDLLDYEAIYFLFQEILDEYNE-RNAKMSIVLFEDCLEHLTR 2558
+ FGDY +++I Y+++ D + + + + L+E+N A MS+V+F +EH++R
Sbjct: 2361 LFFGDYFKPESDQKI--YDEITDLKQLTVVMEHYLEEFNNISKAPMSLVMFRFAIEHISR 2418
Query: 2559 THRILRMDRGNAMXXXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMYL 2618
R+L+ D+G+ + KL+ F E+++I +T+NY N +++D+K++ L
Sbjct: 2419 ICRVLKQDKGHLLLVGIGGSGRQSAAKLSTFMNAYELYQIEITKNYAGNDWREDLKKIIL 2478
Query: 2619 QLGVDNKKTVFLFTAAQILEEGFLEFINNILMIGMIPALFGDDEKDSIINSVRNDSSDAG 2678
Q+GV K TVFLF QI +E F+E IN +L G +P +F DEK I+ ++ + G
Sbjct: 2479 QVGVATKSTVFLFADNQIKDESFVEDINMLLNTGDVPNIFPADEKADIVEKMQTAARTQG 2538
>AJ320497-1|CAC60121.1| 4523|Homo sapiens axonemal beta heavy chain
dynein type 11 protein.
Length = 4523
Score = 721 bits (1782), Expect = 0.0
Identities = 444/1430 (31%), Positives = 735/1430 (51%), Gaps = 79/1430 (5%)
Query: 753 FFEDIISDLNTHVKFVDVGASLRMTINMNIKGLEDFKLVMATITQVQQMTITAEVKYRGM 812
F D +++L +K D G + + GL D + + + Q+ T + + +
Sbjct: 1138 FVIDSLNELQEFIKETDSGLQRELNEGDH-DGLVDIMVHLLAVRSRQRAT---DELFEPL 1193
Query: 813 QEIFHMLKQHGINVTDEDLQFAKSLEASWGSLYQTSLFRGNTLEQTKEKFSKLNVVEISN 872
+E +L+ +G + ++ + L W + + + + + L +
Sbjct: 1194 KETITLLESYGQKMPEQVYIQLEELPERWETTKKIAATVRHEVSPLHNAEVTLIRKKCIL 1253
Query: 873 FLKELDDFVEKFDNEGPATVEDDMDRGLLLMEEYGKYIDELESRKKMLQAAEQLFDNPLA 932
F + +F E+F + P + + +++ + ++ LE +Q + +LF+ L
Sbjct: 1254 FDAKQAEFRERFRHYAPLGF--NAENPYTALDKANEELEALEEEMLQMQESTRLFEVALP 1311
Query: 933 DFSNFNRTKADYSAMDQIYKIYKAQKNAREVWAKTLWVNLNPQALVDGIEQFFK-----E 987
++ + + + + ++ + + + + W KT W ++ + + + +F K E
Sbjct: 1312 EYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQMDVELRRFAKASSITE 1371
Query: 988 YRKLPKIVRLSSTGLMLDLKMKQFKGVVPLMVSLKNEAMRERHWKELMAKTGQDFDMSPD 1047
L K VR+ L+ +K + + L++ A+R+RHW +LM G F ++ +
Sbjct: 1372 IWSLNKEVRVWDAYTGLEGTVKDMTASLRAITELQSPALRDRHWHQLMKAIGVKFLIN-E 1430
Query: 1048 RFTLENMFAMELHKYQDVAEEIVNHAIKELAIERGVKDVQETWANISFSVSRHFNRGEDR 1107
TL ++ A+ LH+ +D IV+ A+KEL E+ + ++ +TWA + FS H+ G
Sbjct: 1431 ATTLADLLALRLHRVEDDVRRIVDKAVKELGTEKVITEISQTWATMKFSYEVHYRTGIP- 1489
Query: 1108 GYTLNPCDDIVVKLDDDSMSLQSMAASQFIGPFLTVVQTWEHRLSLISEIIEEWMATQRK 1167
L + + L+ + + LQ++ S+++ F+ V +W+++L++ +I WM QR
Sbjct: 1490 --LLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNIADLVIFTWMEVQRT 1547
Query: 1168 WLYLEGIFV-GGDIRTQLPEEAKKFDDIDRAFRKIMLDTAKRLNVVDCCTIGGRLEEFVN 1226
W +LE IFV DIR QL ++A++FD +D F+++M TAK NV++ E+ +
Sbjct: 1548 WSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELMFKTAKVENVLEATCRPNLYEKLKD 1607
Query: 1227 LGLGLQSSKIIRSASSDVTRKQINLSQAIAWADRASLSLVPRSHLHAKAQAKRDTFSCVQ 1286
L L + ++ + + K+I + + L ++ + AQ K+ T +
Sbjct: 1608 LQSRLSLCE--KALAEYLETKRIAFPRFYFVSSADLLDILSKG-----AQPKQVTCHLAK 1660
Query: 1287 PMFDNIRALDLYVDH-TNRPVAAKMISAEGEIMDFRNVVYTEGRVEDWMNLVLVEMRHTN 1345
+FD+I L + + A M S E E + F+ G VE W+ + M+ T
Sbjct: 1661 -LFDSIADLQFEDNQDVSAHRAVGMYSKEKEYVPFQAECECVGHVETWLLQLEQTMQETV 1719
Query: 1346 KFITKKAIFYYGKNWKVPRTDWILEYQGMVCLAANGVWWTAETEETFLRIKKGNKRAMKE 1405
+ +AI Y + PR WI ++ V L ++ +WWT + F R+++G + A+K+
Sbjct: 1720 RHSITEAIVAYEEK---PRELWIFDFPAQVALTSSQIWWTTDVGIAFSRLEEGYETALKD 1776
Query: 1406 HLQQQNEQLDGLVVKVRQDLSSNDRLKFRTITTIDVHARDIIEGFVRDN--ITEAAEFEW 1463
++Q QL+ L+ + +L DR K TI TIDVHARD++ + + F W
Sbjct: 1777 FHKKQISQLNTLITLLLGELPPGDRQKIMTICTIDVHARDVVAKLISQKQVVVSPQAFTW 1836
Query: 1464 ESQLRFYWLKKDDNLWIRQCTGVFEYGYEYMGLNGRLVITPLTDRIYLTITQALTMQLXX 1523
SQLR W + ++ C F+Y YEY+G + RLVITPLTDR Y+T+TQ+L + +
Sbjct: 1837 LSQLRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPRLVITPLTDRCYITLTQSLHLTMSG 1896
Query: 1524 XXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNR 1583
DL +ALG++ V NC E MD++++G I GL Q GAWGCFDEFNR
Sbjct: 1897 APAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNR 1956
Query: 1584 IDISVLSVISTQLQCIRSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVG 1643
I + VLSV++ Q++ I A+ + KRF G+ I + VG
Sbjct: 1957 ISVEVLSVVAVQVKMIHDAIRNRKKRFVF-------------------LGEAITLKPSVG 1997
Query: 1644 IFITMNPGYAGRTELPESVKALFRPVVCILPDLEMICQISLFSDGFLTAKVLAKKMTVLY 1703
IFITMNPGYAGRTELPE++KALFRP + PD+E+IC+I L ++GF+ A+ LA+K LY
Sbjct: 1998 IFITMNPGYAGRTELPENLKALFRPCAMVAPDIELICEILLVAEGFVDARALARKFITLY 2057
Query: 1704 KVAREQLSKQSHYDWGLRALTAVLRMAGKLRRDSPGLSEIMVLMRALRDMNHPKFVFEDV 1763
+ +E LSKQ HYDWGLRA+ +VL +AG L+R E VLMRALRD N PK V +D+
Sbjct: 2058 TLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDI 2117
Query: 1764 PLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEKDGYVVLPHQVDKVVQLYETMMTRHCT 1823
P+FLGL+ DLFP L+ PR F V + + + KVVQL E + RH
Sbjct: 2118 PVFLGLVGDLFPALDVPRRRKLHFEQMVRQSTLELRLQPEESFILKVVQLEELLAVRHSV 2177
Query: 1824 MLVGPTGGGKTVILHCLVKAQTNLGLPTKLTVVNPKACSVIELYGILDPVTRDWTD---- 1879
+VG G GK+ IL L + N+ +NPKA + EL+G + TR+W D
Sbjct: 2178 FVVGNAGTGKSKILRTLNRTYVNMKQKPVWNDLNPKAVTTDELFGFIHHATREWKDGKIV 2237
Query: 1880 -----GLYSKIFREMNRPAEKNERRYSLFDGDVDALWIENMNSVMDDNKLLTLANGERIR 1934
GL+S I RE + + ++ + DGD+D +WIE++N+VMDDNK+LTLA+ ERI
Sbjct: 2238 YSYFIGLFSSILREQAN-LKHDGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIA 2296
Query: 1935 LAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGYEPYWERWLSTRSNEEEREQLSGL 1994
L P+ LLFE+ L A+PATVSRAG+++V+P++LG+ PY W+ R ++ E+ L+ L
Sbjct: 2297 LTPFMRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASWIDRRRHQSEKANLTIL 2356
Query: 1995 FEHYVPGAINYIVFGMFGLQQQTPLKTIVPQTPLNLVMQLCYMISGLLPNNEDTNMEIDK 2054
F+ YVP ++ + +T KTI +LV LC ++ LL E+ + K
Sbjct: 2357 FDKYVPACLDKL---------RTSFKTITSIPESSLVQTLCVLLECLL-TPENVPSDSPK 2406
Query: 2055 TVVECVFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVEDNPEKKATTKHFPMGFPTL 2114
V E F+ + + G ++ + D+ + +K+ FP T+
Sbjct: 2407 EVYEVYFVFACIWAFGGTLLQDQISDYQADFSRWW---------QKEMKAVKFP-SQGTI 2456
Query: 2115 YDYCLELTTKLWEAWDWLVPEYEHDRDMKFPAILVPTVDTLRLTWLIKIM 2164
+DY ++ TK W + ++ D D+ +LV T +T RL + ++++
Sbjct: 2457 FDYYVDHKTKKLLPWADKIAQFTMDPDVPLQTVLVHTTETARLRYFMELL 2506
Score = 576 bits (1421), Expect = e-163
Identities = 339/1106 (30%), Positives = 576/1106 (52%), Gaps = 30/1106 (2%)
Query: 2683 KCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKIPEEFRPIIVEHVVHVHMSVAR 2742
+ R FP +VN T IDW WP++AL++V+ F+ + + I + I + HVH +V
Sbjct: 3002 RARKFPAIVNCTAIDWFHAWPQEALVSVSRRFIEETKGIEPVHKDSISLFMAHVHTTVNE 3061
Query: 2743 YSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQLE 2802
S + RR+NY TPK +++ ++ + LL +K + + ERL G+ K+ Q+
Sbjct: 3062 MSTRYYQNERRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVG 3121
Query: 2803 DLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVEKX 2862
DL A+LA Q+ + + + E L+ +I TE ++T + ++
Sbjct: 3122 DLKARLASQEAELQLRNHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQR 3181
Query: 2863 XXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVII-----RGIK 2917
+ +++E+++F PP AV V V+++ R K
Sbjct: 3182 ECEADLLKAEPALVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVPK 3241
Query: 2918 DVSWKGAKGMMAD-PNFLRNLQEMNCDLITQAQVKAVKTHMKKSKKLDT--MQQISKAGY 2974
D SWK AK M +FL+ L + + I + +K V H K + + ++ S A
Sbjct: 3242 DRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAAA 3301
Query: 2975 GLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQKTLDGLNNR 3034
GL +V ++ + + A L ++ +++ L + L L
Sbjct: 3302 GLCAWVINIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTAS 3361
Query: 3035 YETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSRLIGNCLLA 3094
+E A + QEE + + + A++L+ L +++ RW + + + ++ L G+ LL
Sbjct: 3362 FEKATAEKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLT 3421
Query: 3095 TSFLSYTGPFSFSFRQTMIYEDWLGDVMER-GIPLTLPFTIERNLTNEVEVSGWNSEGLP 3153
+F+SY GPF+ +RQ +++ W+ + ++ IPLT + LT++ ++ WN+EGLP
Sbjct: 3422 AAFVSYVGPFTRQYRQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGLP 3481
Query: 3154 PDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLRQLEMAIK 3213
D +S +N + T R+PL IDPQ Q + WIK K + LKV FL +E A+
Sbjct: 3482 SDRMSTENAAILTHCERWPLVIDPQQQGIKWIKNKYGMD-LKVTHLGQKGFLNAIETALA 3540
Query: 3214 YGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPNFRMYLTTKLANPQ 3273
+G +L +++ E IDPV+D +L +N ++ G+ ++ +G E +++ NFR+ L TKLANP
Sbjct: 3541 FGDVILIENLEETIDPVLDPLLGRNT-IKKGK-YIRIGDKECEFNKNFRLILHTKLANPH 3598
Query: 3274 FNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANKSLLSGLED 3333
+ P A+ ++N+TVT GLE QLL+ VV ER DLE+ + L + K L LED
Sbjct: 3599 YKPELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLED 3658
Query: 3334 SLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRDGYRPVAKR 3393
LL L+ + G+ LD+ +LV LE TK+ AE+ K+ A+ + I + R+ YRP+A R
Sbjct: 3659 DLLLRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPLAAR 3718
Query: 3394 GSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDMLTKNVYDY 3453
S+L+FV++D+ +N +YQ+SL ++ +F ++ +A + R+ +++ +T V+ Y
Sbjct: 3719 ASLLYFVINDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFLY 3778
Query: 3454 GCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLEKSARSSPAPWMPAQGW 3513
+FE+ KL F QM ++ + + +LDF ++ V + SP ++ +Q W
Sbjct: 3779 TSQALFEKDKLTFLSQMAFQILLRKKEIDPLELDFLLRFTV---EHTHLSPVDFLTSQSW 3835
Query: 3514 QDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLKPFELLMLLR 3573
I ++ + F + D+ ++W++W +S+ PE ++P +++K + L+LLR
Sbjct: 3836 SAIKAIA--VMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKK-SLIQKLILLR 3892
Query: 3574 CFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPGSDPTADLMK 3633
R DR+ AL +++ +G +Y+ + L E+++P TP+ FILSPG D DL
Sbjct: 3893 AMRPDRMTYALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEI 3952
Query: 3634 LADRCGF--GGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFLRELEKQL 3691
L R GF GKF +SLGQGQE A LE A G W+ILQN HL+ +L LEK L
Sbjct: 3953 LGKRLGFTIDSGKFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLL 4012
Query: 3692 ELMTK-PHPEYRLWLTTDPTPT-----FPIGILQRSLK---EPPNGLKLNLRNTYFKMRA 3742
E ++ H +YR++++ + PT P G+L+ S+K EPP G+ NL +
Sbjct: 4013 ERFSQGSHRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQ 4072
Query: 3743 RALEECPHPQ-FKKLVYVLAFFHAVV 3767
LE C Q FK +++ L +FHA V
Sbjct: 4073 DTLEICSKEQEFKSILFSLCYFHACV 4098
Score = 182 bits (442), Expect = 3e-44
Identities = 107/386 (27%), Positives = 188/386 (48%), Gaps = 15/386 (3%)
Query: 3768 QVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDEYIDF 3827
++MYGG Y+EE++ L + A + PP + Y +
Sbjct: 4148 EIMYGGHITDDWDRKLCRVYLEEFVNPSLTEDELML------APGFAAPPYLDYAGYHQY 4201
Query: 3828 IDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEAGGAM--SREDFIDNI 3885
I+ + +P ++GLHPNAEI + + ++ L+E+QP+ + +G + S E+ + N+
Sbjct: 4202 IEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDELGQSTEEKVKNV 4261
Query: 3886 AVDVLSKLPTLYEIWRVRKQFEMNITPTLVVLLQELERFNRLISRMGSTLSLLRKALAGE 3945
D+L KLP + + + ++ N +P ++V QE ER N LI + +L L +L GE
Sbjct: 4262 LDDILEKLPEEFNMAEIMQK-NSNRSPYVLVCFQECERMNILIREIRISLEQLDLSLKGE 4320
Query: 3946 IGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTKQYTDWA-TVEEPVV 4004
+ + ++ ++L +P W LA + GL W + + R ++ W + P V
Sbjct: 4321 LALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWTQDLTLPAV 4380
Query: 4005 IWLSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVTSWVSADEIEERPVTGCYVRGLY 4064
+WLSG P+S+L A +Q R WPLD+ T+ T + + ++ P G Y+ GL+
Sbjct: 4381 VWLSGFFNPQSFLTAIMQTMARKNEWPLDK-TRLTADVTKKTKEDYGHPPREGAYLHGLF 4439
Query: 4065 LEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRTPVYTTSQRRNAMGV 4124
+EGARWD G + + K L +P+++ + + + T PVY T R G
Sbjct: 4440 MEGARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYECPVYRTKLR----GP 4495
Query: 4125 GLVFESDLWTTEHCSHWILQGVCLIM 4150
++ L + E + W+L GV L++
Sbjct: 4496 SYIWTFRLKSEEKTAKWVLAGVALLL 4521
Score = 134 bits (323), Expect = 8e-30
Identities = 67/179 (37%), Positives = 103/179 (57%), Gaps = 3/179 (1%)
Query: 2495 VLRDPMLFGDYRNALDEEEIRYYEDLLDYEAIYFLFQEILDEYNERNAKMSIVLFEDCLE 2554
+L+ P++ Y + D + +Y + D+E + + E LD YNE NA M +VLFED ++
Sbjct: 2786 LLQQPLI---YCHFADRGKDPHYMPVKDWEVLKTILTETLDNYNELNAAMHLVLFEDAMQ 2842
Query: 2555 HLTRTHRILRMDRGNAMXXXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMK 2614
H+ R RILR +G A+ +LAA+ G E+F+IT+T Y + D+
Sbjct: 2843 HVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLA 2902
Query: 2615 RMYLQLGVDNKKTVFLFTAAQILEEGFLEFINNILMIGMIPALFGDDEKDSIINSVRND 2673
+Y++ G N TVFL T AQ+L+E FL IN++L G IP LF D++ D II+ + N+
Sbjct: 2903 NLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNE 2961
Score = 118 bits (284), Expect = 5e-25
Identities = 80/266 (30%), Positives = 127/266 (47%), Gaps = 28/266 (10%)
Query: 2167 IIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMPIVSHNNQCVP 2226
I+ ++ F+ T+S +Q+ LE +EK+ +GP K+++ FIDDMNM
Sbjct: 2539 IVSRVPFNYYTTSTALQKILEKPLEKKAGHNYGPGGNKKLIYFIDDMNM----------- 2587
Query: 2227 SLCSTRVQTLLSHPLVDTYGTQQPIALLKLLFERKGFYDRGKDLNWKNLKDIGFLAAMGK 2286
P VD YGT QP L++ + +YDR K + K + + ++A M
Sbjct: 2588 -------------PEVDLYGTVQPHTLIRQHIDYGHWYDRQKVM-LKEIHNCQYVACMNP 2633
Query: 2287 AGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSILKGHFE--IFPEEIQGIVEKIVQM 2344
G + PR F+V+ FPS + L IY I HF+ F I ++Q
Sbjct: 2634 MVGSFT-ISPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQQQAFAPSILRSGPTLIQA 2692
Query: 2345 TLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMCLTHANYFSEKRTVVRCWRNEFTRV 2404
T+ ++ ++ PT KFHYIFNLRDLS + G+ ++ W +E RV
Sbjct: 2693 TIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASPECLKGPLDLIHLWLHESARV 2752
Query: 2405 ICDRLINQQDNELMRGHIQEHVARYF 2430
D+LI+++D +L + + E +YF
Sbjct: 2753 YGDKLIDKKDCDLFQRRMLETAYKYF 2778
Score = 43.6 bits (98), Expect = 0.016
Identities = 48/274 (17%), Positives = 107/274 (39%), Gaps = 11/274 (4%)
Query: 6 YKETRRNIELSGKGARWEFDQPLLFTRTDYIGTVARDLGDIIQVLIDFERIFGLEL---K 62
Y++ + + K W+F L+F R D + DI ++FE++ LE K
Sbjct: 437 YRKKLASYFMGRKLRPWDFQSHLVFCRFDKFLDRLIKIEDIFATTLEFEKLERLEFGGTK 496
Query: 63 SIISDPTQIDDVRKRVKNLVYPIRTVDFSVFVFDNKENWDVIMGDFWNEVRYLEDEAKNY 122
I + Q+ ++ + + L + + N E ++ F ++ +
Sbjct: 497 GAILN-GQVHEMSEELMELCKLFKQSTYDPSDCTNME-FESDYVAFKSKTLEFDRRLGTI 554
Query: 123 INQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEITAIEDKFTRYR 182
I ++F N E A +L F F + + S + ++ F E+ + + +
Sbjct: 555 ICEAFFNCNGLEAAFKLLTIFGNFLEKPVVMEIFSLHYSTLVHMFNTELDVCKQLYNEHM 614
Query: 183 K-----NPPLLRNHPPVAGAISWARALFNKMKQPIMKFQKVSELNECEQKKE-AFLQYKA 236
K + L +N P +G + WA+ + +++ F + L + +Y
Sbjct: 615 KQIECGHVVLNKNMPFTSGNMKWAQQVLQRLQMFWSNFASLRYLFLGNPDHALVYQKYVE 674
Query: 237 FSKIIKEYEDTKYKEWVQDASLFCDNMMKKNILK 270
+ ++ ++E Y EW + C+ + + ++K
Sbjct: 675 MTTLLDQFESRIYNEWKSNVDEICEFNLNQPLVK 708
>AB037831-1|BAA92648.2| 4355|Homo sapiens KIAA1410 protein protein.
Length = 4355
Score = 669 bits (1654), Expect = 0.0
Identities = 442/1404 (31%), Positives = 718/1404 (51%), Gaps = 98/1404 (6%)
Query: 798 VQQMTITAEVKYRGMQEIFHMLKQHGINVTDEDLQFAKSLEASWGS--LYQTSLFRGNTL 855
+ + + E + + + + ++ + N++ +D K + ++W S L Q L + +
Sbjct: 899 IPERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFN-DKWIASNWPSKILGQIELVQQQHV 957
Query: 856 EQTKEKFSKLNVVEISNFLKELDDFVEKFDNEGPATVEDDMDRGLLLMEEYGKYIDELES 915
E +EKF K+ +++ +NF ++L+ + G ++ ++ R + E + +L+
Sbjct: 958 ED-EEKFRKIQIMDQNNFQEKLEGL--QLVVAG-FSIHVEISRAHEIANEVRRVKKQLKD 1013
Query: 916 RKKMLQA---AEQLFDNPLADFSNFNRTKADYSAMDQIYKIYKAQKNAREVWAKTLWVNL 972
+++ E++F P+ ++ +R ++ ++ E W +
Sbjct: 1014 CQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAI 1073
Query: 973 NPQALVDGIEQFFKEYRKLPKIVR----LSSTGLMLDLKMKQFKGVVPLMVSLKNEAMRE 1028
+ + L + + FK K K + L + ++++FK +PL+ L+N MR
Sbjct: 1074 DAEQLEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRI 1133
Query: 1029 RHWKELMAKTGQDFDMSPD-RFTLENMFAMELHKYQDVAEEIVNHAIKELAIERGVKDVQ 1087
RHW+ L + + ++ P T M L + + ++ A KE AIE+ + ++
Sbjct: 1134 RHWETLSNQI--NINVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKME 1191
Query: 1088 ETWANISFSVSRHFNRGEDRGYTLNPCDDIVVKLDDDSMSLQSMAASQFIGPFLTVVQTW 1147
+ W+ I F+V + + D Y L D+ LDD + Q+M+ S + PF + +W
Sbjct: 1192 KEWSTILFNVLPY--KATDT-YILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSW 1248
Query: 1148 EHRLSLISEIIEEWMATQRKWLYLEGIFVGGDIRTQLPEEAKKFDDIDRAFRKIMLDTAK 1207
E++L L E++EEW+ QR WLYLE IF DI QLP E+K++ ++R ++KIM + +
Sbjct: 1249 ENKLKLTQEVLEEWLNCQRSWLYLEPIFSSEDINQQLPVESKRYQTMERIWKKIMKNAYE 1308
Query: 1208 RLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASSDVTRKQINLSQAIAWADRASLSLVP 1267
V++ C+ L+ + L + + S + K+ + +D L ++
Sbjct: 1309 NREVINVCSDLRMLDSLRDCNKILDL--VQKGLSEYLETKRSAFPRFYFLSDDELLEILS 1366
Query: 1268 RSHLHAKAQAKRDTFSCVQPMFDNIRALDLYVDHTNRPVAAKMISAEGEIMDFRNVVYTE 1327
++ Q ++ F+NI L L+ + M SAEGE + +Y
Sbjct: 1367 QTKDPTAVQPH------LRKCFENIARL-LFQEDLE---ITHMYSAEGEEVQLCFSIYPS 1416
Query: 1328 GRVEDWMNLVLVEMRHTNKFITKKAIFYYGKNWKVPRTDWILEYQGMVCLAANGVWWTAE 1387
VEDW+ V M+ + I +KAI Y +PRT W+L + G V +A +WT E
Sbjct: 1417 SNVEDWLREVERSMKASVHDIIEKAIRAYPT---MPRTQWVLNWPGQVTIAGCQTYWTME 1473
Query: 1388 TEETFLRIKKGNKRAMKEHLQQQNEQLDGLVVKVRQDLSSNDRLKFRTITTIDVHARDII 1447
E ++ GN R+ + Q +QL LV VR LS R + I+VHA+D++
Sbjct: 1474 VAEA---LEAGNLRS--QLFPQLCQQLSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVV 1528
Query: 1448 EGFVRDNITEAAEFEWESQLRFYWLKKDDNLWIRQCTGVFEYGYEYMGLNGRLVITPLTD 1507
+++N+ +F+W SQLR+YW D L+IR F YGYEY+G +GRLVITPLTD
Sbjct: 1529 SKLIQENVVSVNDFQWISQLRYYWTNND--LYIRAVNAEFIYGYEYLGNSGRLVITPLTD 1586
Query: 1508 RIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDFRAVGQILA 1567
R YLT+T AL ++ DL KAL + VV NC + +DF A+G+
Sbjct: 1587 RCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFK 1646
Query: 1568 GLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLKRFTVNTDVLKPSQKFGRLK 1627
GL GAW CFDEFNRIDI VLSV++ Q+ I+ A +++RF
Sbjct: 1647 GLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQRVERFMFE-------------- 1692
Query: 1628 TKRRAGQEIAMDSKVGIFITMNPGYAGRTELPESVKALFRPVVCILPDLEMICQISLFSD 1687
G EI + +FITMNPGYAGRTELP+++KALFRPV ++PD MI +ISL+S
Sbjct: 1693 -----GVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMITEISLYSF 1747
Query: 1688 GFLTAKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTAVLRMAGKLRRDSPGLSEIMVLM 1747
GF A VLAKK+T +K++ EQLS Q HYD+G+RA+ V+ AG L+R++P ++E ++ +
Sbjct: 1748 GFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELICL 1807
Query: 1748 RALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEKDGYVVLPHQV 1807
RA+RD+N PKF+ ED+ LF G++ DLFP ++ Y + A+ E + +
Sbjct: 1808 RAIRDVNVPKFLQEDLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEGFL 1867
Query: 1808 DKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNL-GLPT---------KLTVVN 1857
K +QLYET + RH MLVGPTG GK+ L A T+L G P+ V+N
Sbjct: 1868 TKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYVLN 1927
Query: 1858 PKACSVIELYGILDPVTRDWTDGLYSKIFREMNRPAEKNERRYSLFDGDVDALWIENMNS 1917
PK+ ++ +LYG D +T +WTDG++S R ++ N++ Y +FDG VDA+WIENMN+
Sbjct: 1928 PKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKWY-MFDGPVDAIWIENMNT 1986
Query: 1918 VMDDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGYEPYWER 1977
V+DDNK L L++GE I+L +++FEV DL ASPATVSR GMV+++P LG P+ E
Sbjct: 1987 VLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFIEC 2046
Query: 1978 WLSTRSN--EEEREQLSGLFEHYVPGAINYIVFGMFGLQQQTPLKTIVPQTPLNLVMQLC 2035
WL + E LF ++ +I+++ ++ +K ++ T NL M L
Sbjct: 2047 WLRKLPPLLKPYEEHFKALFVSFLEESISFV---------RSSVKEVIASTNCNLTMSLL 2097
Query: 2036 YMI----SGLLPNNEDTNMEIDK--TVVECV---FMVSMYNSLGAAIVDNGRYDFDNYIK 2086
++ LP + +K +VE + F+ S+ S+GA +GR F ++++
Sbjct: 2098 KLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATGDSSGRTSFSHWLR 2157
Query: 2087 -KACPMMLVEDNPEKKATTKH-----FPMGFPTLYDYCLELTTKLWEAWDWLVPEYEHDR 2140
K L PE+ + G D E W W +
Sbjct: 2158 LKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVP 2217
Query: 2141 DMKFPAILVPTVDTLRLTWLIKIM 2164
D + I+VPT+DT++++ L+ ++
Sbjct: 2218 DTNYCNIIVPTMDTVQMSHLLDML 2241
Score = 524 bits (1292), Expect = e-147
Identities = 271/712 (38%), Positives = 419/712 (58%), Gaps = 15/712 (2%)
Query: 3061 KLMSGLSSEQKRWTEDLAALYVEQSRLIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGD 3120
+L++GLS E+ RW E + L + + G+ L+A F++Y GPF+ +R T++Y+ W+
Sbjct: 3211 QLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYR-TVLYDSWVKQ 3269
Query: 3121 VMERGIPLTLPFTIERNLTNEVEVSGWNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQ 3180
+ +P T T+ L N V++ W GLP D LSV+NG++ + R+ IDPQ+Q
Sbjct: 3270 LRSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQ 3329
Query: 3181 ALTWIKKKEAKNNLKVLSFNDPQFLRQLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIK 3240
A WIK E N L V +D FLR +E AI++G P L ++V E +DP ++ VL K
Sbjct: 3330 ANKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTY 3389
Query: 3241 VESGRTFVMLGSTEVDYDPNFRMYLTTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLS 3300
+ G T + LG T + Y +FRMY+TTKL NP + P K +IN+T++ GLEDQLL
Sbjct: 3390 KQQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLG 3449
Query: 3301 VVVRAERSDLEEQRESLIIETSANKSLLSGLEDSLLRELATSTGNMLDNVELVNTLENTK 3360
VV ER DLEE + LII + + L +ED +L L++S GN +D++EL+ LE +K
Sbjct: 3450 QVVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASK 3509
Query: 3361 SKAAEVMEKLELAEATTKDIEKLRDGYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLD 3420
KAAE+ K+ +AE T KDI+ R Y PVA R ILFF +SD+A V+ MYQYSL +L+
Sbjct: 3510 MKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLN 3569
Query: 3421 VFSFSLRKAMPNVILVKRLKNIIDMLTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDN 3480
+F + + L KR+ NI LT ++Y C +FE+HKL+F+F + +++ +E
Sbjct: 3570 IFLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGK 3629
Query: 3481 VSQAQLDFFIK-GNVSLEKSARSSPAP-WMPAQGWQDIMKLSSDFPDPFATLPDDITKFL 3538
++Q++ + + G++S+ +PAP W+ + W+DI+ L S+ P F++ D K L
Sbjct: 3630 INQSEWRYLLSGGSISI---MTENPAPDWLSDRAWRDILAL-SNLP-TFSSFSSDFVKHL 3684
Query: 3539 EEWQEWFDSDTPESAEIPNNYREKLKPFELLMLLRCFRVDRIYRALTDYITVTMGEEYIT 3598
E++ FDS P +P + + L F+ L++LRC R D++ A+ D++ + +I
Sbjct: 3685 SEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIE 3744
Query: 3599 PPVISLDMIVEQTTPFTPVVFILSPGSDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAA 3658
P +L ++ + + TP++F+LSPG+DP ADL K A+ F K +SLGQGQ A
Sbjct: 3745 PQTANLSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKF-SKKLSAISLGQGQGPRA 3803
Query: 3659 LSLLEGAISHGQWLILQNCHLLVSFLRELEKQLELMT--KPHPEYRLWLTTDPTPTFPIG 3716
+++ +I G+W+ QNCHL S++ LE+ +E + K H ++RLWLT+ P+ FP+
Sbjct: 3804 EAMMRSSIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVS 3863
Query: 3717 ILQRSLK---EPPNGLKLNLRNTYFKMRARALEECPH-PQFKKLVYVLAFFH 3764
ILQ K EPP G++ NL +Y + L C +FK L+ L FH
Sbjct: 3864 ILQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFH 3915
Score = 206 bits (503), Expect = 1e-51
Identities = 118/392 (30%), Positives = 197/392 (50%), Gaps = 11/392 (2%)
Query: 3768 QVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDEYIDF 3827
++ YGG +E++ D P H Y + IPP + Y+ +
Sbjct: 3968 EINYGGRVTDDWDRRCIMNILEDFYNP---DVLSPEHSYSASGIYHQIPPTYDLHGYLSY 4024
Query: 3828 IDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEAGGAMSREDFIDNIAV 3887
I +LPL + PE+FGLH NA I + + G +I+LQP++S AG + RE+ ++++
Sbjct: 4025 IKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSSSAG-SQGREEIVEDVTQ 4083
Query: 3888 DVLSKLPTLYEIWRVRKQFEMNITPTL-VVLLQELERFNRLISRMGSTLSLLRKALAGEI 3946
++L K+P + V ++ + ++ VL+QE+ R+NRL+ + TL L KAL G +
Sbjct: 4084 NILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLV 4143
Query: 3947 GMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTKQYTDWATVEEPVVIW 4006
M + L+ ++ SL+N +P++W A A + K L W+ + R W P V W
Sbjct: 4144 VMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFW 4203
Query: 4007 LSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVTSWVSADEIEERPVTGCYVRGLYLE 4066
+SG P+++L +Q R + +D + F + + E+ +RP GCY+ GL+LE
Sbjct: 4204 ISGFFFPQAFLTGTLQNFARKFVISID-TISFDFKVMFEAPSELTQRPQVGCYIHGLFLE 4262
Query: 4067 GARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRTPVYTTSQRRNAM---- 4122
GARWD + L S PK L TE+ +++++P K + Q+ P+Y T R +
Sbjct: 4263 GARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTG 4322
Query: 4123 -GVGLVFESDLWTTEHCSHWILQGVCLIMNTD 4153
V ++ T + HWI +GV LI D
Sbjct: 4323 HSTNYVIAVEIPTHQPQRHWIKRGVALICALD 4354
Score = 147 bits (356), Expect = 9e-34
Identities = 93/263 (35%), Positives = 137/263 (52%), Gaps = 36/263 (13%)
Query: 2164 MESIIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMPIVSHNNQ 2223
++ I + FS+RTS+ Q ++S ++KR K FGPP+G+ + FIDD+NM
Sbjct: 2272 LDYISHFLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNM-------- 2323
Query: 2224 CVPSLCSTRVQTLLSHPLVDTYGTQQPIALLKLLFERKGFYDRGKDLNWKNLKDIGFLAA 2283
P ++TYG Q PI LL+ + G+YDR +KNL DI F+ A
Sbjct: 2324 ----------------PALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCA 2367
Query: 2284 MGKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSIL----------KGHFEIFP-- 2331
MG GGGRN V PR + F+ + E + + I+ +IL K + E P
Sbjct: 2368 MGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGA 2427
Query: 2332 EEIQGIVEKIVQMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMCLTHANYFSEKR 2391
I E +V+ T+ +Y I +L PTPAK HY FNLRDLS++ GM + ++
Sbjct: 2428 PHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQV 2487
Query: 2392 TVVRCWRNEFTRVICDRLINQQD 2414
++R W +E RV DRL+N++D
Sbjct: 2488 QLLRLWYHENCRVFRDRLVNEED 2510
Score = 141 bits (341), Expect = 6e-32
Identities = 95/398 (23%), Positives = 176/398 (44%), Gaps = 17/398 (4%)
Query: 2682 AKCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKIPEEFRPI--IVEHVVHVHMS 2739
A+ R FP LVN TIDW WP +AL +VA VFL ++ ++ I +++ V++H S
Sbjct: 2750 ARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGLIQVCVYIHQS 2809
Query: 2740 VARYSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANV 2799
V++ E+L L R+NYVTPK Y++ L + L+ +K + R+K GL K+ +
Sbjct: 2810 VSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSE 2869
Query: 2800 QLEDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAV 2859
+ + L ++ E K+ + +++I T + E++K
Sbjct: 2870 DVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQA 2929
Query: 2860 EKXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVIIRGIK-- 2917
KND+TE+R+ PP V++V E V I++GIK
Sbjct: 2930 IADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPK 2989
Query: 2918 -----------DVSWKGAKGMMADP-NFLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLD 2964
D W+ KG++ DP +FL +L + + D I +KA++ ++ + +
Sbjct: 2990 KVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQPYIDNEEFQPA 3049
Query: 2965 TMQQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRL 3024
T+ ++SKA + ++V A+ Y L + + +
Sbjct: 3050 TIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLREV 3109
Query: 3025 QKTLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKL 3062
+ + + +Y + +++EL+ + + +RL A K+
Sbjct: 3110 EDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKV 3147
Score = 118 bits (285), Expect = 3e-25
Identities = 60/174 (34%), Positives = 102/174 (58%), Gaps = 3/174 (1%)
Query: 2499 PMLFGDYRNALDEEEIRYYEDLLDYEAIYFLFQEILDEYNERN-AKMSIVLFEDCLEHLT 2557
P+L+GD+ + +++ YE + + + +E +++YN+ N AK+ +VLF D + H+
Sbjct: 2537 PILYGDFMSP--GSDVKSYELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHIC 2594
Query: 2558 RTHRILRMDRGNAMXXXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMY 2617
R R LR GNA+ +LA+ A E F+I +++NY + ++DD+K++
Sbjct: 2595 RISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVL 2654
Query: 2618 LQLGVDNKKTVFLFTAAQILEEGFLEFINNILMIGMIPALFGDDEKDSIINSVR 2671
L+ G+ N FLF+ QI E FLE INN+L G IP L+ DE+D I++++R
Sbjct: 2655 LKAGLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMR 2708
>AB046823-1|BAB13429.2| 1659|Homo sapiens KIAA1603 protein protein.
Length = 1659
Score = 668 bits (1650), Expect = 0.0
Identities = 367/1102 (33%), Positives = 591/1102 (53%), Gaps = 27/1102 (2%)
Query: 2687 FPGLVNNTTIDWQFPWPKQALLAVANVFLADVQ-KIPEEFRPIIVEHVVHVHMSVARYSA 2745
FP L++ TIDW WPK AL+AV+ FL E + +V+ + VA
Sbjct: 137 FPALISGCTIDWFSRWPKDALVAVSEHFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCV 196
Query: 2746 EFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQLEDLN 2805
++ R RR+ +VTPK Y+ F+ Y + EK + R+ GL K+ EA+ + L+
Sbjct: 197 DYFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAALS 256
Query: 2806 AKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVEKXXXX 2865
+L ++ + + +++LKE++ + I+ +K
Sbjct: 257 KELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKVKDRAQAIVDSISKDKAIAE 316
Query: 2866 XXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVII--RGIKDV---- 2919
+DI +R+ PP + + +CV+++ R + V
Sbjct: 317 EKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDL 376
Query: 2920 -------SWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLDTMQQISK 2971
SW+ + +M NFL+NLQ+ D I + ++ + + + ++T +++
Sbjct: 377 EKSCTMPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCG 436
Query: 2972 AGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQKTLDGL 3031
GL + A+ + + + A+ L E+D Q LD +
Sbjct: 437 NVAGLCSWTKAMASFFSINKEVLPLKANLVVQENRHLLAMQDLQKAQAELDDKQAELDVV 496
Query: 3032 NNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSRLIGNC 3091
YE AM +Q L E+ + ++ A L+SGL+ E++RWTE + RL+G+
Sbjct: 497 QAEYEQAMTEKQTLLEDAERCRHKMQTASTLISGLAGEKERWTEQSQEFAAQTKRLVGDV 556
Query: 3092 LLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSGWNSEG 3151
LLAT+FLSY+GPF+ FR ++ DW ++ R IP + L + +S WN +G
Sbjct: 557 LLATAFLSYSGPFNQEFRDLLL-NDWRKEMKARKIPFGKNLNLSEMLIDAPTISEWNLQG 615
Query: 3152 LPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLRQLEMA 3211
LP D+LS+QNGI+ T+ASR+PL IDPQTQ WIK KE++N L++ S N F LE +
Sbjct: 616 LPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIKNKESRNELQITSLNHKYFRNHLEDS 675
Query: 3212 IKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTF-VMLGSTEVDYDPNFRMYLTTKLA 3270
+ G P+L +DV E +DP +DNVLE+N +++G TF V +G EVD FR+Y+TTKL
Sbjct: 676 LSLGRPLLIEDVGEELDPALDNVLERNF-IKTGSTFKVKVGDKEVDVLDGFRLYITTKLP 734
Query: 3271 NPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANKSLLSG 3330
NP + P A+ +I++TVT++GLEDQLL V+ E+ +LE++R L+ + +ANK +
Sbjct: 735 NPAYTPEISARTSIIDFTVTMKGLEDQLLGRVILTEKQELEKERTHLMEDVTANKRRMKE 794
Query: 3331 LEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRDGYRPV 3390
LED+LL L ++ G+++++ L+ L NTK A EV +KLE++ T I R+ YRPV
Sbjct: 795 LEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEVTQKLEISAETEVQINSAREEYRPV 854
Query: 3391 AKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDMLTKNV 3450
A RGSIL+F++++M VN MYQ SL +L +F SL +++ + I KR+ NII+ +T V
Sbjct: 855 ATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTYEV 914
Query: 3451 YDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLE-KSARSSPAPWMP 3509
Y Y G++E HK LF+ + +K++ + V + IKG SL+ K+ P+ W+
Sbjct: 915 YKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEFLTLIKGGASLDLKACPPKPSKWIL 974
Query: 3510 AQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLKPFELL 3569
W ++++LS F+ + D I++ + W+ WFD + PE +PN Y + L F L
Sbjct: 975 DITWLNLVELSK--LRQFSDVLDQISRNEKMWKIWFDKENPEEEPLPNAYDKSLDCFRRL 1032
Query: 3570 MLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPGSDPTA 3629
+L+R + DR YI +MGE+Y ++ L+ E++ P TP++ +LS GSDPT
Sbjct: 1033 LLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLEKTWEESDPRTPLICLLSMGSDPTD 1092
Query: 3630 DLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFLRELEK 3689
++ L R + +Y+S+GQGQE A LL+ +++G W +LQNCHL + F+ EL
Sbjct: 1093 SIIALGKRLKI---ETRYVSMGQGQEVHARKLLQQTMANGGWALLQNCHLGLDFMDELMD 1149
Query: 3690 QLELMTKPHPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLNLRNTYFKMRARALE 3746
+ H +RLW+TT+ FPI +LQ S+K +PP GL+ L+ TY + L+
Sbjct: 1150 IIIETELVHDAFRLWMTTEVHKQFPITLLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLD 1209
Query: 3747 ECPHPQFKKLVYVLAFFHAVVQ 3768
Q+K ++Y +AF H+ VQ
Sbjct: 1210 VSSGSQWKPMLYAVAFLHSTVQ 1231
Score = 199 bits (486), Expect = 2e-49
Identities = 127/399 (31%), Positives = 195/399 (48%), Gaps = 15/399 (3%)
Query: 3754 KKLVYVLAFFHAVVQVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDY 3813
KK V + + ++ YGG T+ + + E +F F FY+ Y
Sbjct: 1269 KKGVSWTTIRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSENMFGP--DFSFYQGYN--- 1323
Query: 3814 VIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEAG 3873
IP D Y+ +I +LP ++PEVFGLHPNA+I Y S+ +++ ++ +QP+ + G
Sbjct: 1324 -IPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDVLDTILGIQPKDTSGG 1382
Query: 3874 GAMSREDFIDNIAVDVLSKLPTLYEIWRVRKQFEM--NITPTLVVLLQELERFNRLISRM 3931
G +RE + +A D+L KLP Y + V+++ + P + L QE++R R++S +
Sbjct: 1383 GDETREAVVARLADDMLEKLPPDYVPFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLV 1442
Query: 3932 GSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTK 3991
STL+ L+ A+ G I M L + +F+ ++P W+ A LG W I R
Sbjct: 1443 RSTLTELKLAIDGTIIMSENLRDALDCMFDARIPAWWKK-ASWVSSTLGFWFTELIERNS 1501
Query: 3992 QYTDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYT-WPLDRSTQFTKVTSWVSADEI 4050
Q+T W P W++G P+ +L A Q R W LD +VT W+ D+I
Sbjct: 1502 QFTSWVFNGRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVLCNEVTKWMK-DDI 1560
Query: 4051 EERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRT 4110
P G YV GLYLEGA WD L S PKVL +P++ I E + L+
Sbjct: 1561 SAPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIRIY-AENNTLRDPRFYSC 1619
Query: 4111 PVYTTSQRRNAMGVGLVFESDLWTTEHCSHWILQGVCLI 4149
P+Y R + + V DL T + HW+L+GV L+
Sbjct: 1620 PIYKKPVRTDLNYIAAV---DLRTAQTPEHWVLRGVALL 1655
Score = 74.9 bits (176), Expect = 6e-12
Identities = 35/82 (42%), Positives = 51/82 (62%)
Query: 2585 KLAAFAAGCEMFEITVTRNYNENTFKDDMKRMYLQLGVDNKKTVFLFTAAQILEEGFLEF 2644
+LA+F AG F+IT+TR+YN + +D+K +Y G K F+FT +I +E FLE+
Sbjct: 2 RLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKDESFLEY 61
Query: 2645 INNILMIGMIPALFGDDEKDSI 2666
+NN+L G + LF DE D I
Sbjct: 62 MNNVLSSGEVSNLFARDEIDEI 83
>AC068919-1|AAY14995.1| 2536|Homo sapiens unknown protein.
Length = 2536
Score = 657 bits (1623), Expect = 0.0
Identities = 363/1114 (32%), Positives = 594/1114 (53%), Gaps = 36/1114 (3%)
Query: 2683 KCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKIPEEFRPIIVEHVVHVHMSVAR 2742
+ R FP LVN TIDW WP+ AL AVA+ FL +++ + EE R ++ H S
Sbjct: 1210 RLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIE-MSEEIRDGCIDMCKSFHTSTID 1268
Query: 2743 YSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQLE 2802
S F + L+R NYVTP Y++ ++ + LL +K + ++ +R + GL K+ A+ Q+
Sbjct: 1269 LSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVA 1328
Query: 2803 DLNAKLAV---QKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAV 2859
+ +L Q + +++ E I++++ S E SK I
Sbjct: 1329 TMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKTEKIVKADETIANEQAMASKAI-- 1386
Query: 2860 EKXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVIIRGIK-- 2917
K DIT ++S +PP V++V E + I++GIK
Sbjct: 1387 -KDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKAD 1445
Query: 2918 ------------DVSWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSKKL-- 2963
+ W AK ++ D FL++L E + D I A + ++ + +
Sbjct: 1446 KIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVP 1505
Query: 2964 DTMQQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDR 3023
+ ++ S A GL K+V A+ Y A++ L +
Sbjct: 1506 EKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKE 1565
Query: 3024 LQKTLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVE 3083
+Q L L + E ++ +L+ + DL ++L A++L+ GL E+ RW+ L
Sbjct: 1566 VQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQL 1625
Query: 3084 QSRLIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVE 3143
L G+ L+++ ++Y G F+ ++RQ ++W R IP + ++ L V
Sbjct: 1626 YINLTGDILISSGVVAYLGAFTSTYRQNQT-KEWTTLCKGRDIPCSDDCSLMGTLGEAVT 1684
Query: 3144 VSGWNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQ 3203
+ WN GLP D S+ NGI+ A R+PL IDPQ+QA WIK E N+L V+ ++P
Sbjct: 1685 IRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPD 1744
Query: 3204 FLRQLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPNFRM 3263
++R LE I++G PVL ++V E +DP+++ +L K + G T + LG + ++Y P+FR
Sbjct: 1745 YVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRF 1804
Query: 3264 YLTTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSA 3323
Y+TTKL NP + P K ++N+ +T +G++DQLL +VV ER DLEE++++LI++ +
Sbjct: 1805 YITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAE 1864
Query: 3324 NKSLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKL 3383
NK L +ED +L L++S GN+L++ + L ++K+ A E+ +K E+AE T K I+
Sbjct: 1865 NKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSKALANEISQKQEVAEETEKKIDTT 1924
Query: 3384 RDGYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNII 3443
R GYRP+A SILFF L+D+A + MYQYSL+ ++++F S+ + + IL KRL+ +
Sbjct: 1925 RMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWFINLFILSIENSEKSEILAKRLQILK 1984
Query: 3444 DMLTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLEKSARSS 3503
D T ++Y C +FE+ KLLFSF + I L E +++A+ F + G + L+ + ++
Sbjct: 1985 DHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLLHERAINKAEWRFLLTGGIGLD-NPYAN 2043
Query: 3504 PAPWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKL 3563
W+P + W +I +L D P F T+ + + + W++ +DS P P + +K
Sbjct: 2044 LCTWLPQKSWDEICRL-DDLP-AFKTIRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDKA 2101
Query: 3564 KPFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSP 3623
F+ ++++RC R D++ L ++I +G +I PP L + P++F+LSP
Sbjct: 2102 NEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSP 2161
Query: 3624 GSDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSF 3683
G+DP A L+K AD G+GG K LSLGQGQ A+ +LE A+ G W++LQNCHL S+
Sbjct: 2162 GADPMAALLKFADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSW 2221
Query: 3684 LRELEKQLELMT--KPHPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLNLRNTYF 3738
+ LEK E ++ HP++R+WLT+ P+P FP+ +LQ +K E P GL+ N+ +Y
Sbjct: 2222 MPTLEKVCEELSPESTHPDFRMWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRSYL 2281
Query: 3739 KMRARALE---ECPHP-QFKKLVYVLAFFHAVVQ 3768
E C P +FKKL+Y L FFHA+VQ
Sbjct: 2282 MDPISDPEFFGSCKKPEEFKKLLYGLCFFHALVQ 2315
Score = 561 bits (1384), Expect = e-158
Identities = 344/997 (34%), Positives = 541/997 (54%), Gaps = 74/997 (7%)
Query: 1475 DDNLWIRQCTGVFEYGYEYMGLNGRLVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXX 1534
+++L + YGYEY+G + RLVITPLTDR Y T+ AL + L
Sbjct: 1 ENHLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKT 60
Query: 1535 XXXXDLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVIST 1594
DLAKA+ CVV NC +G+D+ A+G+ GL CGAW CFDEFNRID+ VLSV++
Sbjct: 61 ETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQ 120
Query: 1595 QLQCIRSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAG 1654
Q+ I+ + D+L G E+ +D +FITMNPGYAG
Sbjct: 121 QILTIQRGI-------NAGADILMFE------------GTELKLDPTCAVFITMNPGYAG 161
Query: 1655 RTELPESVKALFRPVVCILPDLEMICQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQS 1714
R+ELP+++KALFR V ++PD MI +I L+S GF+TA+ L+ K+ Y++ EQLS Q
Sbjct: 162 RSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQH 221
Query: 1715 HYDWGLRALTAVLRMAGKLRRDSPGLSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLF 1774
HYD+G+RA+ +VL AG L+ P +E ++L+R++ D+N PKF+ D+PLF G+ DLF
Sbjct: 222 HYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLF 281
Query: 1775 PGLECPRVGYPEFNAAVLEVLEKDGYVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKT 1834
PG++ P+ Y + AA+ + + +K++Q+YE M+ RH M+VG GGKT
Sbjct: 282 PGVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKT 341
Query: 1835 VILHCLVKAQTNL---GL----PTKLTVVNPKACSVIELYGILDPVTRDWTDGLYSKIFR 1887
L A ++ GL ++TV+NPK+ ++ +LYG D V+ +W+DG+ + FR
Sbjct: 342 SAYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFR 401
Query: 1888 EMNRPAEKNERRYSLFDGDVDALWIENMNSVMDDNKLLTLANGERIRLAPYCSLLFEVGD 1947
+ +R++ +FDG VDA+WIENMN+V+DDNK L L +GE I+++P +L+FE D
Sbjct: 402 AF-ASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMD 460
Query: 1948 LNYASPATVSRAGMVFVDPKNLGYEPY---WERWLSTRSNEEEREQLSGLFEHYVPGAIN 2004
L ASPATVSR GM++++P LG+ P W L + ++E + GLF+ VP ++
Sbjct: 461 LEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVE 520
Query: 2005 YIVFGMFGLQQQTPLKTIVPQTPLNLVMQLCYMISGLLPNNED------TNMEIDKTVVE 2058
+I ++ T K + P + NLV L +I + + D N +++E
Sbjct: 521 FI-------RKHT--KELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETYSLLE 571
Query: 2059 CVFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVE--------DNPEKKATTKHFPMG 2110
+F+ S+ S+GA+ D+ R F+ +++ + + + ++ ++K +
Sbjct: 572 GIFLFSLIWSVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVP 631
Query: 2111 FP---TLYDYCLELTTK---LWEAWDWLVPEYEH-DRDMKFPAILVPTVDTLRLTWLIKI 2163
FP T+YDY + T+ WE W + E +D+ F I+VPT+DT+R + L+++
Sbjct: 632 FPEKGTIYDY--QFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMEL 689
Query: 2164 MESIIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPV----GKRMLVFIDDMNMPIVS 2219
+ + + F T + ++ + K+ + P + + ++ M +
Sbjct: 690 LTTHQKPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLD 749
Query: 2220 HNNQCV--PSLCSTRVQTL--LSHPLVDTYGTQQPIALLKLLFERKGFYDRGKDLNWKNL 2275
+ V P L V + ++ P + YG Q PI LL+ + +YD KD + L
Sbjct: 750 KRRKGVFGPPLGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDL-KDCSMIKL 808
Query: 2276 KDIGFLAAMGKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSILKGHFEI---FPE 2332
DI + AMG GGGRN V PR++ F++ + S+ ++ I+ IL H EI FP+
Sbjct: 809 VDIQIMCAMGPPGGGRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPD 868
Query: 2333 EIQGIVEKIVQMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMCLTHANYFSEKRT 2392
E + +IV T+ LYK + L PTPAK HY+FNLRD SR+ G+CL+
Sbjct: 869 EFLDLTTQIVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEV 928
Query: 2393 VVRCWRNEFTRVICDRLINQQDNELMRGHIQEHVARY 2429
+ R W +E RV DRL++ D + +IQE + Y
Sbjct: 929 IKRLWVHEVLRVYYDRLLDNTDRSWLINYIQEILRNY 965
Score = 99.1 bits (236), Expect = 3e-19
Identities = 54/173 (31%), Positives = 94/173 (54%), Gaps = 3/173 (1%)
Query: 2500 MLFGDYRNALDEEEIRYYEDLLDYEAIYFLFQEILDEYNERNAK-MSIVLFEDCLEHLTR 2558
++F D+ + E+ Y ++ D + + + + L+EYN + K M++VLF +EH++R
Sbjct: 993 LMFCDFHDPKREDT--NYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISR 1050
Query: 2559 THRILRMDRGNAMXXXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMYL 2618
RIL+ R +A+ +LAA A +F++ +++ Y+ + +D+K +
Sbjct: 1051 ISRILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILR 1110
Query: 2619 QLGVDNKKTVFLFTAAQILEEGFLEFINNILMIGMIPALFGDDEKDSIINSVR 2671
+ + VFLFT QI EE FLE ++N+L G IP LF DEK I + +R
Sbjct: 1111 KCAEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMR 1163
Score = 88.2 bits (209), Expect = 6e-16
Identities = 44/140 (31%), Positives = 83/140 (59%), Gaps = 6/140 (4%)
Query: 3808 DYAFD----YVIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLI 3863
DY FD Y +PP G+ YI++ TLPL PE+FG++ NA+I + ++ +++
Sbjct: 2397 DYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNIL 2456
Query: 3864 ELQPQTSEAGGAMSREDFIDNIAVDVLSKLPTLYEIWRVRKQFEMNITPTL-VVLLQELE 3922
Q +++ A GA S ++ ++ +A D+L KLP ++I +++ T ++ VL+QE+
Sbjct: 2457 LTQSRSAGA-GAKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQSMNTVLVQEMG 2515
Query: 3923 RFNRLISRMGSTLSLLRKAL 3942
RFN+L+ + + ++KA+
Sbjct: 2516 RFNKLLKTIRDSCVNIQKAI 2535
>BC117259-1|AAI17260.1| 1581|Homo sapiens LOC200383 protein protein.
Length = 1581
Score = 648 bits (1600), Expect = 0.0
Identities = 350/1117 (31%), Positives = 602/1117 (53%), Gaps = 33/1117 (2%)
Query: 2682 AKCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKIPEEFRPIIVEHVVHVHMSVA 2741
++CR FP LVN TIDW WP++ALL+V+ F + V EE + + V+VH+SV+
Sbjct: 10 SRCRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKLPLMCVNVHLSVS 69
Query: 2742 RYSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQL 2801
+ + LRR Y TP Y++ + YL++L+EK I++ +R+K GL K+ E N+ +
Sbjct: 70 SMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILV 129
Query: 2802 EDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVEK 2861
+ + L+ + ++ ++++ E L+++++ E +++
Sbjct: 130 DKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIA 189
Query: 2862 XXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVIIRGIKDVSW 2921
K DI+EIR F PP+ V V E + I+ K W
Sbjct: 190 DDAQRDLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAKP-DW 248
Query: 2922 KGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSKKL-DTMQQISKAGYGLLKFV 2980
AK ++ D NFL+ L E + + I + ++ ++ + + ++++SKA + +V
Sbjct: 249 PSAKQLLGDSNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWV 308
Query: 2981 TAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQKTLDGLNNRYETAMM 3040
A+ Y + L + +++ + L + Y+ +
Sbjct: 309 RAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVN 368
Query: 3041 RRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSRLIGNCLLATSFLSY 3100
++ L + L RLV A KL + L EQ RW E + E S + GN +A + ++Y
Sbjct: 369 EKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAY 428
Query: 3101 TGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSGWNSEGLPPDELSVQ 3160
G F+ +RQ++I E W+ D IP+ F++ L + E+ WN++GLP D +S +
Sbjct: 429 YGAFTAQYRQSLI-ECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDLISTE 487
Query: 3161 NGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLRQLEMAIKYGMPVLF 3220
NGIL T+ R+PL IDPQ QA WI+ KE+K+ LK++ D FLR LE +I+ G+PVL
Sbjct: 488 NGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLPVLL 547
Query: 3221 QDVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPNFRMYLTTKLANPQFNPAAYA 3280
+++ E +DP ++ +L K I + GR + LG +++DYD NFR Y+TTK+ NP + P
Sbjct: 548 EELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCI 607
Query: 3281 KAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANKSLLSGLEDSLLRELA 3340
K +IN+TVT GLEDQLLS VVR E+ LEEQR LI+ + +K+ L +E+ +LR L
Sbjct: 608 KVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILRMLF 667
Query: 3341 TSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRDGYRPVAKRGSILFFV 3400
TS GN+LDN EL++TL+++K + + +LE AE+T + I R+ YRPVA +GS+++FV
Sbjct: 668 TSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVMYFV 727
Query: 3401 LSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDMLTKNVYDYGCTGIFE 3460
++ ++ ++ MYQYSL + +F+ ++ ++ L +RL +++ Y G+FE
Sbjct: 728 IASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRGLFE 787
Query: 3461 RHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLEKSARSSP-APWMPAQGWQDIMKL 3519
+HKL++SF + +++ + + +S A+ +FF++G+ LEK P APW+P W L
Sbjct: 788 QHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFACCDL 847
Query: 3520 SSDFP-----------DPFATLPDDITKFL--EEWQEWF-----DSDTPESAEIPNN--Y 3559
FP P + ++ ++W+ + D + E + +
Sbjct: 848 EESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQDPW 907
Query: 3560 REKLKPFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVF 3619
L F L+L++C + +++ ALTD++ +G+++I P + L + + + TP+VF
Sbjct: 908 SAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNTPLVF 967
Query: 3620 ILSPGSDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHL 3679
ILS GSDP + A G+ + + +SLGQGQ A +++ A+ G W+ LQNCHL
Sbjct: 968 ILSTGSDPMGAFQRFARESGY-SERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQNCHL 1026
Query: 3680 LVSFLRELEKQLELMTKP----HPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLN 3732
VS++ +E+ ++ T P +RL+L++ P+ TFP+ +LQ S+K EPP GL+ N
Sbjct: 1027 AVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGLRAN 1086
Query: 3733 LRNTYFKMRARALEE-CPHPQFKKLVYVLAFFHAVVQ 3768
+R + +M EE +++++++ + FFHA++Q
Sbjct: 1087 IRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQ 1123
Score = 140 bits (339), Expect = 1e-31
Identities = 89/351 (25%), Positives = 159/351 (45%), Gaps = 29/351 (8%)
Query: 3800 FQPFHFYKDYAFD----YVIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAV 3855
F P +DY + Y P E+ D+I+ LPL + PE+FG+H NA + + +
Sbjct: 1195 FSPETLEEDYKYSESGIYFAPMADSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKET 1254
Query: 3856 REMWGHLIELQPQTSEAGGAMSREDFIDNIAVDVLSKLPTLYEIWRVR-----KQFEMNI 3910
+ ++E+QP++S G S ++ + + V +++P E+ K + +
Sbjct: 1255 STLINTILEVQPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRL 1314
Query: 3911 TPTLVVLLQELERFNRLISRMGSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRA 3970
VL QE++RFN L+ + ++L L KA+AG + M ++ V S N Q+P +W
Sbjct: 1315 NSLTTVLGQEVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSN 1374
Query: 3971 LAPATCKGLGGWMDHFIARTKQYTDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYTW 4030
A + K LG W+ I RT W +P W+SG P+ +L +Q R Y
Sbjct: 1375 TAYPSLKPLGSWVKDLILRTSFVDLWLKRGQPKSYWISGFFFPQGFLTGTLQNHARKYNL 1434
Query: 4031 PLDR-STQFTKVTSWVSADEIEE------------------RPVTGCYVRGLYLEGARWD 4071
P+D S +++ + ++ + E P G V G++++ +RWD
Sbjct: 1435 PIDELSFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWD 1494
Query: 4072 VDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRTPVYTTSQRRNAM 4122
E ++ + P + LP+++ P + +K P+Y T R +
Sbjct: 1495 DKEMVIEDALPGQMNPVLPVVHFEPQQNYK-PSPTLYHCPLYKTGARAGTL 1544
>AB051484-1|BAB21788.2| 2182|Homo sapiens KIAA1697 protein protein.
Length = 2182
Score = 648 bits (1600), Expect = 0.0
Identities = 350/1117 (31%), Positives = 602/1117 (53%), Gaps = 33/1117 (2%)
Query: 2682 AKCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKIPEEFRPIIVEHVVHVHMSVA 2741
++CR FP LVN TIDW WP++ALL+V+ F + V EE + + V+VH+SV+
Sbjct: 611 SRCRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKLPLMCVNVHLSVS 670
Query: 2742 RYSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQL 2801
+ + LRR Y TP Y++ + YL++L+EK I++ +R+K GL K+ E N+ +
Sbjct: 671 SMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILV 730
Query: 2802 EDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVEK 2861
+ + L+ + ++ ++++ E L+++++ E +++
Sbjct: 731 DKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIA 790
Query: 2862 XXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVIIRGIKDVSW 2921
K DI+EIR F PP+ V V E + I+ K W
Sbjct: 791 DDAQRDLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAKP-DW 849
Query: 2922 KGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSKKL-DTMQQISKAGYGLLKFV 2980
AK ++ D NFL+ L E + + I + ++ ++ + + ++++SKA + +V
Sbjct: 850 PSAKQLLGDSNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWV 909
Query: 2981 TAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQKTLDGLNNRYETAMM 3040
A+ Y + L + +++ + L + Y+ +
Sbjct: 910 RAMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVN 969
Query: 3041 RRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSRLIGNCLLATSFLSY 3100
++ L + L RLV A KL + L EQ RW E + E S + GN +A + ++Y
Sbjct: 970 EKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAY 1029
Query: 3101 TGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSGWNSEGLPPDELSVQ 3160
G F+ +RQ++I E W+ D IP+ F++ L + E+ WN++GLP D +S +
Sbjct: 1030 YGAFTAQYRQSLI-ECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDLISTE 1088
Query: 3161 NGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLRQLEMAIKYGMPVLF 3220
NGIL T+ R+PL IDPQ QA WI+ KE+K+ LK++ D FLR LE +I+ G+PVL
Sbjct: 1089 NGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLPVLL 1148
Query: 3221 QDVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPNFRMYLTTKLANPQFNPAAYA 3280
+++ E +DP ++ +L K I + GR + LG +++DYD NFR Y+TTK+ NP + P
Sbjct: 1149 EELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCI 1208
Query: 3281 KAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANKSLLSGLEDSLLRELA 3340
K +IN+TVT GLEDQLLS VVR E+ LEEQR LI+ + +K+ L +E+ +LR L
Sbjct: 1209 KVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILRMLF 1268
Query: 3341 TSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRDGYRPVAKRGSILFFV 3400
TS GN+LDN EL++TL+++K + + +LE AE+T + I R+ YRPVA +GS+++FV
Sbjct: 1269 TSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVMYFV 1328
Query: 3401 LSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDMLTKNVYDYGCTGIFE 3460
++ ++ ++ MYQYSL + +F+ ++ ++ L +RL +++ Y G+FE
Sbjct: 1329 IASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRGLFE 1388
Query: 3461 RHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLEKSARSSP-APWMPAQGWQDIMKL 3519
+HKL++SF + +++ + + +S A+ +FF++G+ LEK P APW+P W L
Sbjct: 1389 QHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFACCDL 1448
Query: 3520 SSDFP-----------DPFATLPDDITKFL--EEWQEWF-----DSDTPESAEIPNN--Y 3559
FP P + ++ ++W+ + D + E + +
Sbjct: 1449 EESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQDPW 1508
Query: 3560 REKLKPFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVF 3619
L F L+L++C + +++ ALTD++ +G+++I P + L + + + TP+VF
Sbjct: 1509 SAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNTPLVF 1568
Query: 3620 ILSPGSDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHL 3679
ILS GSDP + A G+ + + +SLGQGQ A +++ A+ G W+ LQNCHL
Sbjct: 1569 ILSTGSDPMGAFQRFARESGY-SERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQNCHL 1627
Query: 3680 LVSFLRELEKQLELMTKP----HPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLN 3732
VS++ +E+ ++ T P +RL+L++ P+ TFP+ +LQ S+K EPP GL+ N
Sbjct: 1628 AVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNTFPVTVLQNSVKVTNEPPKGLRAN 1687
Query: 3733 LRNTYFKMRARALEE-CPHPQFKKLVYVLAFFHAVVQ 3768
+R + +M EE +++++++ + FFHA++Q
Sbjct: 1688 IRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAIIQ 1724
Score = 172 bits (419), Expect = 2e-41
Identities = 115/386 (29%), Positives = 190/386 (49%), Gaps = 24/386 (6%)
Query: 2055 TVVECVFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVEDNPEKKATTKHFPMGFPTL 2114
T++ F+ SLG + +N FD +I+ +DNP+ + L
Sbjct: 11 TILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQ-----FDDNPDARLPNSG------DL 59
Query: 2115 YDYCLELTTKLWEAWDWLVPEYEHDRDMKFPAILVPTVDTLRLTWLIKIMESIIQQMNFS 2174
+ ++ TK + W+ ++P ++++RD+ F +LVPT DT+R +L++ + ++ + F+
Sbjct: 60 WSIHMDFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFT 119
Query: 2175 SRT---SSMDVQRNLESVVEKR----TKDTFGPPVGKRMLVFIDDMNMPIVSHNNQCVPS 2227
T S+ + L + E F I + + N P
Sbjct: 120 GITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERKRKNILGAPG 179
Query: 2228 LCSTRVQTL---LSHPLVDTYGTQQPIALLKLLFERKGFYDRGKDLNWKNLKDIGFLAAM 2284
+ R+ L+ P +D YG+Q PI LL+ + GFYDR K L WK ++D+ ++A
Sbjct: 180 --NKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNK-LFWKEIQDVTIISAC 236
Query: 2285 GKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSILKGHFEIFPEEIQGIVEKIVQM 2344
GGGRN V PRFI FS+ L PSE++L+ I+ +IL G FP ++ IV+
Sbjct: 237 APPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSDFPPAVKQTASSIVEA 296
Query: 2345 TLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMCLTHANYFSEKRTVVRCWRNEFTRV 2404
++++Y + V+L PTPAK HY+FNLRDLS+ G+ E+ + R + +E RV
Sbjct: 297 SVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIREEIQIFRLFCHECQRV 356
Query: 2405 ICDRLINQQDNELMRGHIQEHVARYF 2430
DRLIN +D + E ++F
Sbjct: 357 FHDRLINNEDKHYFHVILTEMANKHF 382
Score = 140 bits (339), Expect = 1e-31
Identities = 89/351 (25%), Positives = 159/351 (45%), Gaps = 29/351 (8%)
Query: 3800 FQPFHFYKDYAFD----YVIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAV 3855
F P +DY + Y P E+ D+I+ LPL + PE+FG+H NA + + +
Sbjct: 1796 FSPETLEEDYKYSESGIYFAPMADSLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKET 1855
Query: 3856 REMWGHLIELQPQTSEAGGAMSREDFIDNIAVDVLSKLPTLYEIWRVR-----KQFEMNI 3910
+ ++E+QP++S G S ++ + + V +++P E+ K + +
Sbjct: 1856 STLINTILEVQPRSSTGGEGKSNDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRL 1915
Query: 3911 TPTLVVLLQELERFNRLISRMGSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRA 3970
VL QE++RFN L+ + ++L L KA+AG + M ++ V S N Q+P +W
Sbjct: 1916 NSLTTVLGQEVDRFNNLLKLIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSN 1975
Query: 3971 LAPATCKGLGGWMDHFIARTKQYTDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYTW 4030
A + K LG W+ I RT W +P W+SG P+ +L +Q R Y
Sbjct: 1976 TAYPSLKPLGSWVKDLILRTSFVDLWLKRGQPKSYWISGFFFPQGFLTGTLQNHARKYNL 2035
Query: 4031 PLDR-STQFTKVTSWVSADEIEE------------------RPVTGCYVRGLYLEGARWD 4071
P+D S +++ + ++ + E P G V G++++ +RWD
Sbjct: 2036 PIDELSFKYSVIPTYRDQAAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWD 2095
Query: 4072 VDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRTPVYTTSQRRNAM 4122
E ++ + P + LP+++ P + +K P+Y T R +
Sbjct: 2096 DKEMVIEDALPGQMNPVLPVVHFEPQQNYK-PSPTLYHCPLYKTGARAGTL 2145
Score = 139 bits (336), Expect = 2e-31
Identities = 68/186 (36%), Positives = 110/186 (59%), Gaps = 1/186 (0%)
Query: 2494 YVLRDPMLFGDYRNALDEEEIRYYEDLLDYEAIYFLFQEILDEYNERNAK-MSIVLFEDC 2552
Y L P++FGD+ ++ R Y+D+ D E + Q+ LD+YN N K + +V F+D
Sbjct: 390 YFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNPKEVKLVFFQDA 449
Query: 2553 LEHLTRTHRILRMDRGNAMXXXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDD 2612
+EH++R R++R +RGNA+ +LAA G + +I ++R YN ++F +D
Sbjct: 450 IEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHED 509
Query: 2613 MKRMYLQLGVDNKKTVFLFTAAQILEEGFLEFINNILMIGMIPALFGDDEKDSIINSVRN 2672
++++Y GV++K VFLFT QI+ E FLE INNIL G +P LF DE + ++ + R
Sbjct: 510 LRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQVLAATRP 569
Query: 2673 DSSDAG 2678
+ + G
Sbjct: 570 RAKEVG 575
>AK128517-1|BAC87476.1| 901|Homo sapiens protein ( Homo sapiens cDNA
FLJ46675 fis, clone TRACH3009701, weakly similar to Homo
sapiens dynein, axonemal, heavy polypeptide 9 (DNAH9). ).
Length = 901
Score = 636 bits (1571), Expect = 0.0
Identities = 325/859 (37%), Positives = 508/859 (59%), Gaps = 12/859 (1%)
Query: 2887 KNDITEIRSFATPPEAVQVVCECVVIIRGIKDVSWKGAKGMMADPNFLRNLQEMNCDLIT 2946
K DI EI+S+ PP V++V + V+I+RG + +W AK + + NF+++L + D I+
Sbjct: 45 KKDIGEIKSYGRPPAQVEIVMQAVMILRG-NEPTWAEAKRQLGEQNFIKSLINFDKDNIS 103
Query: 2947 QAQVKAVKTHMKKSK-KLDTMQQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXX 3005
+K + + + + D + ++S A L +V A+ Y
Sbjct: 104 DKVLKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALA 163
Query: 3006 XYSEAVNYLASLNREIDRLQKTLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSG 3065
E LA ++ + + L+ L +Y+ + +++EL+++++ M +L A L+SG
Sbjct: 164 QLREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSG 223
Query: 3066 LSSEQKRWTEDLAALYVEQSRLIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERG 3125
L+ E+ RW E + L + L+G+CLLA +FLSY GPF ++R ++ + W+G + E
Sbjct: 224 LAGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQ 283
Query: 3126 IPLTLPFTIERNLTNEVEVSGWNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWI 3185
+P + F I+ L N +V WN +GLP D S +NGI+ TR +R+ L IDPQ QAL WI
Sbjct: 284 VPCSPSFAIDNFLCNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWI 343
Query: 3186 KKKEAKNNLKVLSFNDPQFLRQLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGR 3245
K E LK++ +LR LE AI +G PVL Q+V EY+DP ++ +L K++ GR
Sbjct: 344 KNMEGGQGLKIIDLQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGR 403
Query: 3246 TFVMLGSTEVDYDPNFRMYLTTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRA 3305
+ +G EV+Y+ NFR Y+TTKL+NP ++P AK ++N+ V QGLE QLL +VVR
Sbjct: 404 LLMRIGDKEVEYNTNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRK 463
Query: 3306 ERSDLEEQRESLIIETSANKSLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAE 3365
ER +LEEQ++SL+I +A K L LED +LR L +TG++LD+V+LVNTL +K A E
Sbjct: 464 ERPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATE 523
Query: 3366 VMEKLELAEATTKDIEKLRDGYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFS 3425
V E+LE +E T + + R+ YRP A+R SILFFVL+DM ++ MYQ+SL +Y+ +F S
Sbjct: 524 VTEQLETSETTEINTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILS 583
Query: 3426 LRKAMPNVILVKRLKNIIDMLTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQ 3485
+ K+ + L R+ + D T VY Y C +FERHKLLFSF M K+ ++ ++ +
Sbjct: 584 IDKSHRSNKLEDRIDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDE 643
Query: 3486 LDFFIKGNVSLEKSAR-SSP-APWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQE 3543
+FF++G V L++ + +P + W+ W +I +L D F L + ++ +W
Sbjct: 644 YNFFLRGGVVLDREGQMDNPCSSWLADAYWDNITEL--DKLTNFHGLMNSFEQYPRDWHL 701
Query: 3544 WFDSDTPESAEIPNNYREKLKPFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVIS 3603
W+ + PE A +P + + ++++R R DR+ +T +I +G +I PPV++
Sbjct: 702 WYTNAAPEKAMLPGEWENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLN 761
Query: 3604 LDMIVEQTTPFTPVVFILSPGSDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLE 3663
+ ++E +TP +P+VFILSPG DPT+ L++LA+ G +F LSLGQGQ A LL
Sbjct: 762 MKSVLEDSTPRSPLVFILSPGVDPTSALLQLAEHMGM-AQRFHALSLGQGQAPIAARLLR 820
Query: 3664 GAISHGQWLILQNCHLLVSFLRELEKQLELM--TKPHPEYRLWLTTDPTPTFPIGILQRS 3721
++ G W+ L NCHL +S++ L+K +E + PHP +RLWL++ P P FPI ILQ S
Sbjct: 821 EGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVS 880
Query: 3722 LK---EPPNGLKLNLRNTY 3737
+K EPP GLK N+ Y
Sbjct: 881 IKMTTEPPKGLKANMTRLY 899
>AY682080-1|AAT74625.1| 4646|Homo sapiens dynein, cytoplasmic, heavy
polypeptide 1 protein.
Length = 4646
Score = 556 bits (1372), Expect = e-157
Identities = 381/1202 (31%), Positives = 606/1202 (50%), Gaps = 85/1202 (7%)
Query: 833 FAKSLEASWGSLYQTSLFRGNTLEQTKEKFSKLNVVEISNFLKELDDFVEKFDNEGPATV 892
+ ++E WG+ + + ++Q V E D + ++ P T
Sbjct: 1210 YIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTDWEKTKPVTG 1269
Query: 893 EDDMDRGLLLMEEY-GKYIDELESRKKMLQAAE--QLFDNPLADFSNFNRTKADYSAMDQ 949
+ L + Y GK+ + R+K +A E +L D L S R + A+++
Sbjct: 1270 NLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSE-ERVQV---ALEE 1325
Query: 950 IYKIYKAQKNAREVWAKT------LWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLM 1003
+ + +VW + WV++ P+ L ++ + + P +R ++
Sbjct: 1326 LQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASYEF 1385
Query: 1004 LDLKMKQFKGVVPLMVSLKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMELHKYQ 1063
+ +K + + L++ LK+EA+++RHWK+LM + ++ +S TL ++ ++L K +
Sbjct: 1386 VQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVS--ELTLGQIWDVDLQKNE 1443
Query: 1064 DVAEEIVNHAIKELAIERGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVVKLDD 1123
+ ++++ A E+A+E +K ++E W + + N+ + DD+ K+ +
Sbjct: 1444 AIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCR----LIRGWDDLFNKVKE 1499
Query: 1124 DSMSLQSMAASQFIGPFLTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGG-DIRT 1182
S+ +M S + F +WE +L+ I + + W+ QR+W+YLEGIF G DI+
Sbjct: 1500 HINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKH 1559
Query: 1183 QLPEEAKKFDDIDRAFRKIMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASS 1242
LP E ++F I F +M +K V+D I G L L KI ++
Sbjct: 1560 LLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLL--GKIQKALGE 1617
Query: 1243 DVTRKQINLSQAIAWADRASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYVDHT 1302
+ R++ + + D L ++ S AK Q + MF + ++ L D++
Sbjct: 1618 YLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKH------FKKMFAGVSSIILNEDNS 1671
Query: 1303 NRPVAAKMISAEGEIMDFRNVV-YTEG-RVEDWMNLVLVEMRHT-NKFITKKA--IFYYG 1357
V + S EGE + F+ V TE ++ +W+ LV EMR T K + + + +G
Sbjct: 1672 ---VVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFG 1728
Query: 1358 KNWKV-PRT--DWILEYQGMVCLAANGVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQ- 1413
K + P T WI +YQ + + + + W+ E ET L G A H N +
Sbjct: 1729 KATSIDPNTYITWIDKYQAQLVVLSAQIAWS-ENVETALSSMGGGGDAAPLHSVLSNVEV 1787
Query: 1414 -LDGLVVKVRQDLSSNDRLKFRTITTIDVHARDIIEGFVRDNITEAAEFEWESQLRFYWL 1472
L+ L V + R K + T VH RD+ ++ I A FEW SQ+RFY+
Sbjct: 1788 TLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFD 1847
Query: 1473 KKDDN----LWIRQCTGVFEYGYEYMGLNGRLVITPLTDRIYLTITQALTMQLXXXXXXX 1528
K + L I+ F YG+EY+G+ +LV TPLTDR YLT+TQAL +L
Sbjct: 1848 PKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGP 1907
Query: 1529 XXXXXXXXXXDLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISV 1588
L LG +V NC E DF+A+G+I GLCQ GAWGCFDEFNR++ +
Sbjct: 1908 AGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERM 1967
Query: 1589 LSVISTQLQCIRSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITM 1648
LS +S Q+QCI+ AL R N + K S T +++ + + IFITM
Sbjct: 1968 LSAVSQQVQCIQEAL-----REHSNPNYDKTSAPI----TCELLNKQVKVSPDMAIFITM 2018
Query: 1649 NPGYAGRTELPESVKALFRPVVCILPDLEMICQISLFSDGFLTAKVLAKKMTVLYKVARE 1708
NPGYAGR+ LP+++K LFR + PD ++I Q+ L+S GF TA+VLA K+ +K+ E
Sbjct: 2019 NPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDE 2078
Query: 1709 QLSKQSHYDWGLRALTAVLRMAGKLRRD---------------------SPGLSEIMVLM 1747
QLS QSHYD+GLRAL +VL AG ++R+ + L E +L+
Sbjct: 2079 QLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILI 2138
Query: 1748 RALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEK------DGYV 1801
+++ + PK V ED+PL L+ D+FPG++ R + +V ++ DG
Sbjct: 2139 QSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEE 2198
Query: 1802 VLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNL-GLPTKLTVVNPKA 1860
V V+KV+QLY+ H M+VGP+G GK++ L+KA L G+ +++PKA
Sbjct: 2199 VGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKA 2258
Query: 1861 CSVIELYGILDPVTRDWTDGLYSKIFREM--NRPAEKNERRYSLFDGDVDALWIENMNSV 1918
S LYG LDP TR+WTDGL++ + R++ + E +R++ +FDGDVD W+EN+NSV
Sbjct: 2259 ISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSV 2318
Query: 1919 MDDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGYEPYWERW 1978
+DDNKLLTL NGER+ L P ++FEV DL YA+ ATVSR GMV+ L + + +
Sbjct: 2319 LDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNF 2378
Query: 1979 LS 1980
L+
Sbjct: 2379 LA 2380
Score = 403 bits (993), Expect = e-111
Identities = 285/1124 (25%), Positives = 530/1124 (47%), Gaps = 58/1124 (5%)
Query: 2688 PGLVNNTTIDWQFPWPKQALLAVANVFLA--DVQK---IPEEFRPI-------------- 2728
P L N ++W W +AL V F + D++K I ++ P+
Sbjct: 3083 PALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREA 3142
Query: 2729 IVEHVVHVHMSVARYSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLK 2788
IV V VH ++ + +A R R +TP+HY+DF+ +Y L +EK + + Q L
Sbjct: 3143 IVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLN 3202
Query: 2789 GGLAKIAEANVQLEDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXX 2848
GL KI E Q+E+L L ++ + + LK++ +
Sbjct: 3203 VGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQE 3262
Query: 2849 EITEQSKVIAVEKXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCE 2908
++ +Q +VIA ++ K + E+RS A PP AV++ E
Sbjct: 3263 QLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALE 3322
Query: 2909 CVVIIRGIKDVSWKGAKGMMADPNFLRNLQEMNCDLITQA-QVKAVKTHMKK-SKKLDTM 2966
+ ++ G WK + ++ NF+ + + + I+ A + K K +M S + +
Sbjct: 3323 SICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIV 3382
Query: 2967 QQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQK 3026
+ S A ++K+ A L Y + + + I L+
Sbjct: 3383 NRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEA 3442
Query: 3027 TLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSR 3086
++ Y + Q ++ + + ++ + L+ LS+E++RW + + S
Sbjct: 3443 SIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMST 3502
Query: 3087 LIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSG 3146
+ G+CLL+ +F++Y G F RQ ++ W + + I L+N E
Sbjct: 3503 IAGDCLLSAAFIAYAGYFDQQMRQN-LFTTWSHHLQQANIQFRTDIARTEYLSNADERLR 3561
Query: 3147 WNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLR 3206
W + LP D+L +N I+ R +R+PL IDP QA +I + + SF D F +
Sbjct: 3562 WQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRK 3621
Query: 3207 QLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPNFRMYLT 3266
LE A+++G P+L QDV Y DPV++ VL + ++ GR + LG ++D P+F ++L+
Sbjct: 3622 NLESALRFGNPLLVQDVESY-DPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLS 3680
Query: 3267 TKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANKS 3326
T+ +F P ++ +N+TVT L+ Q L+ V++AER D++E+R L+ +
Sbjct: 3681 TRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQL 3740
Query: 3327 LLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRDG 3386
L LE SLL+ L G +LD+ ++ TLEN K +AAEV K+E + +++E +
Sbjct: 3741 RLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQ 3800
Query: 3387 YRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDML 3446
Y P++ S ++F + + ++ +YQYSL +LD++ L + PN+ V + ++
Sbjct: 3801 YLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYE-NPNLKGVTDHTQRLSII 3859
Query: 3447 TKNVYDYG----CTGIFERHKLLFSFQM-DIKLEQS-EDNVSQAQLDFFIKGNVSLEKSA 3500
TK+++ G+ + + F+ + IKL+ + + A+ F++GN + SA
Sbjct: 3860 TKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGN-EIVLSA 3918
Query: 3501 RSSP-APWMPAQGWQDIMKLS--SDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPN 3557
S+P + + + +++LS F D A + D E++ W DS +PE +P
Sbjct: 3919 GSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQAD-----EQFGIWLDSSSPEQT-VPY 3972
Query: 3558 NYREKL------KPFELLMLLRCFRVDRIYRALTDYITVTMGEEYIT---PPVISLDMIV 3608
+ E+ + L+L++ FR DR+ +++ +GE +++ P+ ++
Sbjct: 3973 LWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVG 4032
Query: 3609 EQTTPFTPVVFILSPGSDPTADLMKLADRCGFGGGKFKYLSLGQGQE-GAALSLLEGAIS 3667
+ P TPV+ PG D + + LA + +++G + A + A+
Sbjct: 4033 TEVKPNTPVLMCSVPGYDASGHVEDLAAE---QNTQITSIAIGSAEGFNQADKAINTAVK 4089
Query: 3668 HGQWLILQNCHLLVSFLRELEKQLELMTKPHPEYRLWLTTDPTPTFPIGILQRS---LKE 3724
G+W++L+N HL +L +LEK+L + +PH +RL+LT + P P+ +L+ + E
Sbjct: 4090 SGRWVMLKNVHLAPGWLMQLEKKLHSL-QPHACFRLFLTMEINPKVPVNLLRAGRIFVFE 4148
Query: 3725 PPNGLKLNLRNTYFKMRARALEECPHPQFKKLVYVLAFFHAVVQ 3768
PP G+K N+ T+ + + + P+ + +L ++LA+FHA++Q
Sbjct: 4149 PPPGVKANMLRTFSSIPVSRICKSPNER-ARLYFLLAWFHAIIQ 4191
Score = 81.0 bits (191), Expect = 8e-14
Identities = 40/158 (25%), Positives = 75/158 (47%)
Query: 2521 LDYEAIYFLFQEILDEYNERNAKMSIVLFEDCLEHLTRTHRILRMDRGNAMXXXXXXXXX 2580
+D E + + L + E + +VLF + L+H+ R RI R +G+ +
Sbjct: 2884 VDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGK 2943
Query: 2581 XXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMYLQLGVDNKKTVFLFTAAQILEEG 2640
+ A+ G +++I V R Y F +D++ + + G N+K F+ + +L+ G
Sbjct: 2944 TTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSG 3003
Query: 2641 FLEFINNILMIGMIPALFGDDEKDSIINSVRNDSSDAG 2678
FLE +N +L G +P LF DE +++ + + G
Sbjct: 3004 FLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEG 3041
Score = 66.1 bits (154), Expect = 3e-09
Identities = 70/329 (21%), Positives = 137/329 (41%), Gaps = 16/329 (4%)
Query: 2114 LYDYCLELTTKLWEAWDWLVPEYEHD-RDMKFPAILVPTVDTLR-----LTWLIKIMESI 2167
+ DY + ++ + W W VP+ E + + P ++VPT+DT+R TWL + +
Sbjct: 2534 IIDYEVSISGE-WSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLV 2592
Query: 2168 IQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMPIVSHNNQCVPS 2227
+ S +T ++ +E + + +L D + N +
Sbjct: 2593 LCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAP 2652
Query: 2228 LCSTRVQTL----LSHPLVDTYGTQQPIALLKLLFERKGFYDRGKDLNWKNLKDIGFLAA 2283
+ + L ++ P +D YGTQ+ I+ ++ + E GFY R D W L+ I F+ A
Sbjct: 2653 VQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFY-RTSDQTWVKLERIQFVGA 2711
Query: 2284 MG-KAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSILKGHFEIFPEEIQGIVEKIV 2342
GR + RF+ V + +P +L IY + + + P ++ E +
Sbjct: 2712 CNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIP-SLRTYAEPLT 2770
Query: 2343 QMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMC-LTHANYFSEKRTVVRCWRNEF 2401
++ Y + E + HYI++ R+++R G+ ++R W +E
Sbjct: 2771 AAMVEFY-TMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEA 2829
Query: 2402 TRVICDRLINQQDNELMRGHIQEHVARYF 2430
R+ DRL+ ++ +I ++F
Sbjct: 2830 LRLFQDRLVEDEERRWTDENIDTVALKHF 2858
Score = 45.6 bits (103), Expect = 0.004
Identities = 84/377 (22%), Positives = 140/377 (37%), Gaps = 32/377 (8%)
Query: 3766 VVQVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDEYI 3825
+ Q +YGG T++E FD D D +P R+E++
Sbjct: 4247 MAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFV 4306
Query: 3826 DFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEAGGA------MSRE 3879
+++ LP TP GL NAE + +M ++++Q E A +R
Sbjct: 4307 QWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRT 4366
Query: 3880 DFIDNIAVDVLSKLPTLYEIW-RVRKQFEMNITPTLVVLLQELERFNRLISRMGS-TLSL 3937
D + + L T W + Q ++ T+ + L RF +MG+ L
Sbjct: 4367 DSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQD 4426
Query: 3938 LRKALA-------GEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIART 3990
+R+ LA G+ L + L G LP+ W + W+ F R
Sbjct: 4427 VRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERI 4486
Query: 3991 KQY--------TDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVT 4042
KQ + A + + + L GL +PE+Y+ A Q + +W L+ VT
Sbjct: 4487 KQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVT 4546
Query: 4043 SWVSADEIEERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPI-EFHK 4101
+ A V GL L+GA + + K S + T LP+ + + + +
Sbjct: 4547 TSQGA----TLDACSFGVTGLKLQGATCNNN----KLSLSNAISTALPLTQLRWVKQTNT 4598
Query: 4102 LKLQNTLRTPVYTTSQR 4118
K + + PVY R
Sbjct: 4599 EKKASVVTLPVYLNFTR 4615
Score = 40.3 bits (90), Expect = 0.14
Identities = 29/145 (20%), Positives = 63/145 (43%), Gaps = 6/145 (4%)
Query: 80 NLVYP-IRTVDFSVFVFDNKENWDVIMGDFWNEVRYLEDEAKNYINQSFGNLRSSEEALT 138
NL Y ++ VD + E W+ M + + +E + G +++ E
Sbjct: 524 NLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFR 583
Query: 139 VLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEITAIEDKF-TRYRKNPPLLRNH----PP 193
+ +F R IR + ++++ +I ++ DKF +Y ++ +H PP
Sbjct: 584 IFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPP 643
Query: 194 VAGAISWARALFNKMKQPIMKFQKV 218
V+G+I WA+ + ++ + + + V
Sbjct: 644 VSGSIIWAKQIDRQLTAYMKRVEDV 668
Score = 35.9 bits (79), Expect = 3.1
Identities = 25/134 (18%), Positives = 62/134 (46%), Gaps = 3/134 (2%)
Query: 373 LEFQPNFDKDLFLVIHEAELMEQLGFDVPSNVRDVAMQKSRLFYELEALSKIIAKYNKNA 432
L+ + NF ++ + E ++ LGF VP + + A Q ++L+ +L + + Y +
Sbjct: 733 LKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTC 792
Query: 433 SSLSPSETY--LMKRHLLDMERHILPGLTRITWTALGINDYIKDITKGENSLQAVYQQLK 490
+ T L+ +++ I G+ + W + ++ Y++ + + + Q L
Sbjct: 793 EKVEERNTISLLVAGLKKEVQALIAEGIA-LVWESYKLDPYVQRLAETVFNFQEKVDDLL 851
Query: 491 MVEKEIQFLINQLQ 504
++E++I + L+
Sbjct: 852 IIEEKIDLEVRSLE 865
>AB002323-1|BAA20783.3| 4658|Homo sapiens KIAA0325 protein protein.
Length = 4658
Score = 556 bits (1372), Expect = e-157
Identities = 381/1202 (31%), Positives = 606/1202 (50%), Gaps = 85/1202 (7%)
Query: 833 FAKSLEASWGSLYQTSLFRGNTLEQTKEKFSKLNVVEISNFLKELDDFVEKFDNEGPATV 892
+ ++E WG+ + + ++Q V E D + ++ P T
Sbjct: 1222 YIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTDWEKTKPVTG 1281
Query: 893 EDDMDRGLLLMEEY-GKYIDELESRKKMLQAAE--QLFDNPLADFSNFNRTKADYSAMDQ 949
+ L + Y GK+ + R+K +A E +L D L S R + A+++
Sbjct: 1282 NLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSE-ERVQV---ALEE 1337
Query: 950 IYKIYKAQKNAREVWAKT------LWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLM 1003
+ + +VW + WV++ P+ L ++ + + P +R ++
Sbjct: 1338 LQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASYEF 1397
Query: 1004 LDLKMKQFKGVVPLMVSLKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMELHKYQ 1063
+ +K + + L++ LK+EA+++RHWK+LM + ++ +S TL ++ ++L K +
Sbjct: 1398 VQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVS--ELTLGQIWDVDLQKNE 1455
Query: 1064 DVAEEIVNHAIKELAIERGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVVKLDD 1123
+ ++++ A E+A+E +K ++E W + + N+ + DD+ K+ +
Sbjct: 1456 AIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCR----LIRGWDDLFNKVKE 1511
Query: 1124 DSMSLQSMAASQFIGPFLTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGG-DIRT 1182
S+ +M S + F +WE +L+ I + + W+ QR+W+YLEGIF G DI+
Sbjct: 1512 HINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKH 1571
Query: 1183 QLPEEAKKFDDIDRAFRKIMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASS 1242
LP E ++F I F +M +K V+D I G L L KI ++
Sbjct: 1572 LLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLL--GKIQKALGE 1629
Query: 1243 DVTRKQINLSQAIAWADRASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYVDHT 1302
+ R++ + + D L ++ S AK Q + MF + ++ L D++
Sbjct: 1630 YLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKH------FKKMFAGVSSIILNEDNS 1683
Query: 1303 NRPVAAKMISAEGEIMDFRNVV-YTEG-RVEDWMNLVLVEMRHT-NKFITKKA--IFYYG 1357
V + S EGE + F+ V TE ++ +W+ LV EMR T K + + + +G
Sbjct: 1684 ---VVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFG 1740
Query: 1358 KNWKV-PRT--DWILEYQGMVCLAANGVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQ- 1413
K + P T WI +YQ + + + + W+ E ET L G A H N +
Sbjct: 1741 KATSIDPNTYITWIDKYQAQLVVLSAQIAWS-ENVETALSSMGGGGDAAPLHSVLSNVEV 1799
Query: 1414 -LDGLVVKVRQDLSSNDRLKFRTITTIDVHARDIIEGFVRDNITEAAEFEWESQLRFYWL 1472
L+ L V + R K + T VH RD+ ++ I A FEW SQ+RFY+
Sbjct: 1800 TLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFD 1859
Query: 1473 KKDDN----LWIRQCTGVFEYGYEYMGLNGRLVITPLTDRIYLTITQALTMQLXXXXXXX 1528
K + L I+ F YG+EY+G+ +LV TPLTDR YLT+TQAL +L
Sbjct: 1860 PKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGP 1919
Query: 1529 XXXXXXXXXXDLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISV 1588
L LG +V NC E DF+A+G+I GLCQ GAWGCFDEFNR++ +
Sbjct: 1920 AGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERM 1979
Query: 1589 LSVISTQLQCIRSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITM 1648
LS +S Q+QCI+ AL R N + K S T +++ + + IFITM
Sbjct: 1980 LSAVSQQVQCIQEAL-----REHSNPNYDKTSAPI----TCELLNKQVKVSPDMAIFITM 2030
Query: 1649 NPGYAGRTELPESVKALFRPVVCILPDLEMICQISLFSDGFLTAKVLAKKMTVLYKVARE 1708
NPGYAGR+ LP+++K LFR + PD ++I Q+ L+S GF TA+VLA K+ +K+ E
Sbjct: 2031 NPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDE 2090
Query: 1709 QLSKQSHYDWGLRALTAVLRMAGKLRRD---------------------SPGLSEIMVLM 1747
QLS QSHYD+GLRAL +VL AG ++R+ + L E +L+
Sbjct: 2091 QLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILI 2150
Query: 1748 RALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEK------DGYV 1801
+++ + PK V ED+PL L+ D+FPG++ R + +V ++ DG
Sbjct: 2151 QSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEE 2210
Query: 1802 VLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNL-GLPTKLTVVNPKA 1860
V V+KV+QLY+ H M+VGP+G GK++ L+KA L G+ +++PKA
Sbjct: 2211 VGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKA 2270
Query: 1861 CSVIELYGILDPVTRDWTDGLYSKIFREM--NRPAEKNERRYSLFDGDVDALWIENMNSV 1918
S LYG LDP TR+WTDGL++ + R++ + E +R++ +FDGDVD W+EN+NSV
Sbjct: 2271 ISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSV 2330
Query: 1919 MDDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGYEPYWERW 1978
+DDNKLLTL NGER+ L P ++FEV DL YA+ ATVSR GMV+ L + + +
Sbjct: 2331 LDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNF 2390
Query: 1979 LS 1980
L+
Sbjct: 2391 LA 2392
Score = 403 bits (993), Expect = e-111
Identities = 285/1124 (25%), Positives = 530/1124 (47%), Gaps = 58/1124 (5%)
Query: 2688 PGLVNNTTIDWQFPWPKQALLAVANVFLA--DVQK---IPEEFRPI-------------- 2728
P L N ++W W +AL V F + D++K I ++ P+
Sbjct: 3095 PALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREA 3154
Query: 2729 IVEHVVHVHMSVARYSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLK 2788
IV V VH ++ + +A R R +TP+HY+DF+ +Y L +EK + + Q L
Sbjct: 3155 IVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLN 3214
Query: 2789 GGLAKIAEANVQLEDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXX 2848
GL KI E Q+E+L L ++ + + LK++ +
Sbjct: 3215 VGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQE 3274
Query: 2849 EITEQSKVIAVEKXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCE 2908
++ +Q +VIA ++ K + E+RS A PP AV++ E
Sbjct: 3275 QLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALE 3334
Query: 2909 CVVIIRGIKDVSWKGAKGMMADPNFLRNLQEMNCDLITQA-QVKAVKTHMKK-SKKLDTM 2966
+ ++ G WK + ++ NF+ + + + I+ A + K K +M S + +
Sbjct: 3335 SICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIV 3394
Query: 2967 QQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQK 3026
+ S A ++K+ A L Y + + + I L+
Sbjct: 3395 NRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEA 3454
Query: 3027 TLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSR 3086
++ Y + Q ++ + + ++ + L+ LS+E++RW + + S
Sbjct: 3455 SIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMST 3514
Query: 3087 LIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSG 3146
+ G+CLL+ +F++Y G F RQ ++ W + + I L+N E
Sbjct: 3515 IAGDCLLSAAFIAYAGYFDQQMRQN-LFTTWSHHLQQANIQFRTDIARTEYLSNADERLR 3573
Query: 3147 WNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLR 3206
W + LP D+L +N I+ R +R+PL IDP QA +I + + SF D F +
Sbjct: 3574 WQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRK 3633
Query: 3207 QLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPNFRMYLT 3266
LE A+++G P+L QDV Y DPV++ VL + ++ GR + LG ++D P+F ++L+
Sbjct: 3634 NLESALRFGNPLLVQDVESY-DPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLS 3692
Query: 3267 TKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANKS 3326
T+ +F P ++ +N+TVT L+ Q L+ V++AER D++E+R L+ +
Sbjct: 3693 TRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQL 3752
Query: 3327 LLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRDG 3386
L LE SLL+ L G +LD+ ++ TLEN K +AAEV K+E + +++E +
Sbjct: 3753 RLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQ 3812
Query: 3387 YRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDML 3446
Y P++ S ++F + + ++ +YQYSL +LD++ L + PN+ V + ++
Sbjct: 3813 YLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYE-NPNLKGVTDHTQRLSII 3871
Query: 3447 TKNVYDYG----CTGIFERHKLLFSFQM-DIKLEQS-EDNVSQAQLDFFIKGNVSLEKSA 3500
TK+++ G+ + + F+ + IKL+ + + A+ F++GN + SA
Sbjct: 3872 TKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGN-EIVLSA 3930
Query: 3501 RSSP-APWMPAQGWQDIMKLS--SDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPN 3557
S+P + + + +++LS F D A + D E++ W DS +PE +P
Sbjct: 3931 GSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQAD-----EQFGIWLDSSSPEQT-VPY 3984
Query: 3558 NYREKL------KPFELLMLLRCFRVDRIYRALTDYITVTMGEEYIT---PPVISLDMIV 3608
+ E+ + L+L++ FR DR+ +++ +GE +++ P+ ++
Sbjct: 3985 LWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVG 4044
Query: 3609 EQTTPFTPVVFILSPGSDPTADLMKLADRCGFGGGKFKYLSLGQGQE-GAALSLLEGAIS 3667
+ P TPV+ PG D + + LA + +++G + A + A+
Sbjct: 4045 TEVKPNTPVLMCSVPGYDASGHVEDLAAE---QNTQITSIAIGSAEGFNQADKAINTAVK 4101
Query: 3668 HGQWLILQNCHLLVSFLRELEKQLELMTKPHPEYRLWLTTDPTPTFPIGILQRS---LKE 3724
G+W++L+N HL +L +LEK+L + +PH +RL+LT + P P+ +L+ + E
Sbjct: 4102 SGRWVMLKNVHLAPGWLMQLEKKLHSL-QPHACFRLFLTMEINPKVPVNLLRAGRIFVFE 4160
Query: 3725 PPNGLKLNLRNTYFKMRARALEECPHPQFKKLVYVLAFFHAVVQ 3768
PP G+K N+ T+ + + + P+ + +L ++LA+FHA++Q
Sbjct: 4161 PPPGVKANMLRTFSSIPVSRICKSPNER-ARLYFLLAWFHAIIQ 4203
Score = 81.0 bits (191), Expect = 8e-14
Identities = 40/158 (25%), Positives = 75/158 (47%)
Query: 2521 LDYEAIYFLFQEILDEYNERNAKMSIVLFEDCLEHLTRTHRILRMDRGNAMXXXXXXXXX 2580
+D E + + L + E + +VLF + L+H+ R RI R +G+ +
Sbjct: 2896 VDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGK 2955
Query: 2581 XXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMYLQLGVDNKKTVFLFTAAQILEEG 2640
+ A+ G +++I V R Y F +D++ + + G N+K F+ + +L+ G
Sbjct: 2956 TTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSG 3015
Query: 2641 FLEFINNILMIGMIPALFGDDEKDSIINSVRNDSSDAG 2678
FLE +N +L G +P LF DE +++ + + G
Sbjct: 3016 FLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEG 3053
Score = 66.1 bits (154), Expect = 3e-09
Identities = 70/329 (21%), Positives = 137/329 (41%), Gaps = 16/329 (4%)
Query: 2114 LYDYCLELTTKLWEAWDWLVPEYEHD-RDMKFPAILVPTVDTLR-----LTWLIKIMESI 2167
+ DY + ++ + W W VP+ E + + P ++VPT+DT+R TWL + +
Sbjct: 2546 IIDYEVSISGE-WSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLV 2604
Query: 2168 IQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMPIVSHNNQCVPS 2227
+ S +T ++ +E + + +L D + N +
Sbjct: 2605 LCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAP 2664
Query: 2228 LCSTRVQTL----LSHPLVDTYGTQQPIALLKLLFERKGFYDRGKDLNWKNLKDIGFLAA 2283
+ + L ++ P +D YGTQ+ I+ ++ + E GFY R D W L+ I F+ A
Sbjct: 2665 VQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFY-RTSDQTWVKLERIQFVGA 2723
Query: 2284 MG-KAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSILKGHFEIFPEEIQGIVEKIV 2342
GR + RF+ V + +P +L IY + + + P ++ E +
Sbjct: 2724 CNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIP-SLRTYAEPLT 2782
Query: 2343 QMTLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMC-LTHANYFSEKRTVVRCWRNEF 2401
++ Y + E + HYI++ R+++R G+ ++R W +E
Sbjct: 2783 AAMVEFY-TMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEA 2841
Query: 2402 TRVICDRLINQQDNELMRGHIQEHVARYF 2430
R+ DRL+ ++ +I ++F
Sbjct: 2842 LRLFQDRLVEDEERRWTDENIDTVALKHF 2870
Score = 45.6 bits (103), Expect = 0.004
Identities = 84/377 (22%), Positives = 140/377 (37%), Gaps = 32/377 (8%)
Query: 3766 VVQVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDEYI 3825
+ Q +YGG T++E FD D D +P R+E++
Sbjct: 4259 MAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFV 4318
Query: 3826 DFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEAGGA------MSRE 3879
+++ LP TP GL NAE + +M ++++Q E A +R
Sbjct: 4319 QWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRT 4378
Query: 3880 DFIDNIAVDVLSKLPTLYEIW-RVRKQFEMNITPTLVVLLQELERFNRLISRMGS-TLSL 3937
D + + L T W + Q ++ T+ + L RF +MG+ L
Sbjct: 4379 DSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQD 4438
Query: 3938 LRKALA-------GEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIART 3990
+R+ LA G+ L + L G LP+ W + W+ F R
Sbjct: 4439 VRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERI 4498
Query: 3991 KQY--------TDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVT 4042
KQ + A + + + L GL +PE+Y+ A Q + +W L+ VT
Sbjct: 4499 KQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVT 4558
Query: 4043 SWVSADEIEERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPI-EFHK 4101
+ A V GL L+GA + + K S + T LP+ + + + +
Sbjct: 4559 TSQGA----TLDACSFGVTGLKLQGATCNNN----KLSLSNAISTALPLTQLRWVKQTNT 4610
Query: 4102 LKLQNTLRTPVYTTSQR 4118
K + + PVY R
Sbjct: 4611 EKKASVVTLPVYLNFTR 4627
Score = 40.3 bits (90), Expect = 0.14
Identities = 29/145 (20%), Positives = 63/145 (43%), Gaps = 6/145 (4%)
Query: 80 NLVYP-IRTVDFSVFVFDNKENWDVIMGDFWNEVRYLEDEAKNYINQSFGNLRSSEEALT 138
NL Y ++ VD + E W+ M + + +E + G +++ E
Sbjct: 536 NLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFR 595
Query: 139 VLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEITAIEDKF-TRYRKNPPLLRNH----PP 193
+ +F R IR + ++++ +I ++ DKF +Y ++ +H PP
Sbjct: 596 IFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPP 655
Query: 194 VAGAISWARALFNKMKQPIMKFQKV 218
V+G+I WA+ + ++ + + + V
Sbjct: 656 VSGSIIWAKQIDRQLTAYMKRVEDV 680
Score = 35.9 bits (79), Expect = 3.1
Identities = 25/134 (18%), Positives = 62/134 (46%), Gaps = 3/134 (2%)
Query: 373 LEFQPNFDKDLFLVIHEAELMEQLGFDVPSNVRDVAMQKSRLFYELEALSKIIAKYNKNA 432
L+ + NF ++ + E ++ LGF VP + + A Q ++L+ +L + + Y +
Sbjct: 745 LKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTC 804
Query: 433 SSLSPSETY--LMKRHLLDMERHILPGLTRITWTALGINDYIKDITKGENSLQAVYQQLK 490
+ T L+ +++ I G+ + W + ++ Y++ + + + Q L
Sbjct: 805 EKVEERNTISLLVAGLKKEVQALIAEGIA-LVWESYKLDPYVQRLAETVFNFQEKVDDLL 863
Query: 491 MVEKEIQFLINQLQ 504
++E++I + L+
Sbjct: 864 IIEEKIDLEVRSLE 877
>AC004002-1|AAB96346.2| 1031|Homo sapiens Homo sapiens dynein,
axonemal, heavy polypeptide 11 (DNAH11) protein.
Length = 1031
Score = 524 bits (1293), Expect = e-147
Identities = 312/1021 (30%), Positives = 532/1021 (52%), Gaps = 29/1021 (2%)
Query: 2733 VVHVHMSVARYSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLA 2792
+ HVH +V S + RR+NY TPK +++ ++ + LL +K + + ERL G+
Sbjct: 11 MAHVHTTVNEMSTRYYQNERRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQ 70
Query: 2793 KIAEANVQLEDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITE 2852
K+ Q+ DL A+LA Q+ + + + E L+ +I TE ++T
Sbjct: 71 KLKTTASQVGDLKARLASQEAELQLRNHDAEALITKIGLQTEKVSREKTIADAEERKVTA 130
Query: 2853 QSKVIAVEKXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVI 2912
+ ++ + +++E+++F PP AV V V++
Sbjct: 131 IQTEVFQKQRECEADLLKAEPALVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMV 190
Query: 2913 I-----RGIKDVSWKGAKGMMAD-PNFLRNLQEMNCDLITQAQVKAVKTHMKKSKKLDT- 2965
+ R KD SWK AK M +FL+ L + + I + +K V H K + +
Sbjct: 191 LLAPRGRVPKDRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPN 250
Query: 2966 -MQQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRL 3024
++ S A GL +V ++ + + A L ++ +++ L
Sbjct: 251 LIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDL 310
Query: 3025 QKTLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQ 3084
+ L L +E A + QEE + + + A++L+ L +++ RW + + + ++
Sbjct: 311 DRNLSRLTASFEKATAEKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQE 370
Query: 3085 SRLIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMER-GIPLTLPFTIERNLTNEVE 3143
L G+ LL +F+SY GPF+ +RQ +++ W+ + ++ IPLT + LT++
Sbjct: 371 KTLCGDVLLTAAFVSYVGPFTRQYRQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDAT 430
Query: 3144 VSGWNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQ 3203
++ WN+EGLP D +S +N + T R+PL IDPQ Q + WIK K + LKV
Sbjct: 431 IAAWNNEGLPSDRMSTENAAILTHCERWPLVIDPQQQGIKWIKNKYGMD-LKVTHLGQKG 489
Query: 3204 FLRQLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPNFRM 3263
FL +E A+ +G +L +++ E IDPV+D +L +N ++ G+ ++ +G E +++ NFR+
Sbjct: 490 FLNAIETALAFGDVILIENLEETIDPVLDPLLGRNT-IKKGK-YIRIGDKECEFNKNFRL 547
Query: 3264 YLTTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSA 3323
L TKLANP + P A+ ++N+TVT GLE QLL+ VV ER DLE+ + L +
Sbjct: 548 ILHTKLANPHYKPELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQND 607
Query: 3324 NKSLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKL 3383
K L LED LL L+ + G+ LD+ +LV LE TK+ AE+ K+ A+ + I +
Sbjct: 608 FKIELKYLEDDLLLRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEA 667
Query: 3384 RDGYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNII 3443
R+ YRPVA R S+L+FV++D+ +N +YQ+SL ++ +F ++ +A + R+ ++
Sbjct: 668 RECYRPVAARASLLYFVINDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILM 727
Query: 3444 DMLTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLEKSARSS 3503
+ +T V+ Y +FE+ KL F QM ++ + + +LDF ++ V + S
Sbjct: 728 ESITHAVFLYTSQALFEKDKLTFLSQMAFQILLRKKEIDPLELDFLLRFTV---EHTHLS 784
Query: 3504 PAPWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKL 3563
P ++ +Q W I ++ + F + D+ ++W++W +S+ PE ++P +++K
Sbjct: 785 PVDFLTSQSWSAIKAIA--VMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKK- 841
Query: 3564 KPFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSP 3623
+ L+LLR R DR+ AL +++ +G +Y+ + L E+++P TP+ FILSP
Sbjct: 842 SLIQKLILLRAMRPDRMTYALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSP 901
Query: 3624 GSDPTADLMKLADRCGF--GGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLV 3681
G D DL L R GF GKF +SLGQGQE A LE A G W+ILQN HL+
Sbjct: 902 GVDALKDLEILGKRLGFTIDSGKFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVA 961
Query: 3682 SFLRELEKQLELMTK-PHPEYRLWLTTDPTPT-----FPIGILQRSLK---EPPNGLKLN 3732
+L LEK LE ++ H +YR++++ + PT P G+L+ S+K EPP G+ N
Sbjct: 962 KWLGTLEKLLERFSQGSHRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLAN 1021
Query: 3733 L 3733
L
Sbjct: 1022 L 1022
>AY221994-1|AAO43053.1| 1964|Homo sapiens heat shock regulated-1
protein.
Length = 1964
Score = 524 bits (1292), Expect = e-147
Identities = 271/712 (38%), Positives = 419/712 (58%), Gaps = 15/712 (2%)
Query: 3061 KLMSGLSSEQKRWTEDLAALYVEQSRLIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGD 3120
+L++GLS E+ RW E + L + + G+ L+A F++Y GPF+ +R T++Y+ W+
Sbjct: 889 QLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYR-TVLYDSWVKQ 947
Query: 3121 VMERGIPLTLPFTIERNLTNEVEVSGWNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQ 3180
+ +P T T+ L N V++ W GLP D LSV+NG++ + R+ IDPQ+Q
Sbjct: 948 LRSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQ 1007
Query: 3181 ALTWIKKKEAKNNLKVLSFNDPQFLRQLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIK 3240
A WIK E N L V +D FLR +E AI++G P L ++V E +DP ++ VL K
Sbjct: 1008 ANKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTY 1067
Query: 3241 VESGRTFVMLGSTEVDYDPNFRMYLTTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLS 3300
+ G T + LG T + Y +FRMY+TTKL NP + P K +IN+T++ GLEDQLL
Sbjct: 1068 KQQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLG 1127
Query: 3301 VVVRAERSDLEEQRESLIIETSANKSLLSGLEDSLLRELATSTGNMLDNVELVNTLENTK 3360
VV ER DLEE + LII + + L +ED +L L++S GN +D++EL+ LE +K
Sbjct: 1128 QVVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASK 1187
Query: 3361 SKAAEVMEKLELAEATTKDIEKLRDGYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLD 3420
KAAE+ K+ +AE T KDI+ R Y PVA R ILFF +SD+A V+ MYQYSL +L+
Sbjct: 1188 MKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLN 1247
Query: 3421 VFSFSLRKAMPNVILVKRLKNIIDMLTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDN 3480
+F + + L KR+ NI LT ++Y C +FE+HKL+F+F + +++ +E
Sbjct: 1248 IFLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGK 1307
Query: 3481 VSQAQLDFFIK-GNVSLEKSARSSPAP-WMPAQGWQDIMKLSSDFPDPFATLPDDITKFL 3538
++Q++ + + G++S+ +PAP W+ + W+DI+ L S+ P F++ D K L
Sbjct: 1308 INQSEWRYLLSGGSISI---MTENPAPDWLSDRAWRDILAL-SNLP-TFSSFSSDFVKHL 1362
Query: 3539 EEWQEWFDSDTPESAEIPNNYREKLKPFELLMLLRCFRVDRIYRALTDYITVTMGEEYIT 3598
E++ FDS P +P + + L F+ L++LRC R D++ A+ D++ + +I
Sbjct: 1363 SEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIE 1422
Query: 3599 PPVISLDMIVEQTTPFTPVVFILSPGSDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAA 3658
P +L ++ + + TP++F+LSPG+DP ADL K A+ F K +SLGQGQ A
Sbjct: 1423 PQTANLSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKF-SKKLSAISLGQGQGPRA 1481
Query: 3659 LSLLEGAISHGQWLILQNCHLLVSFLRELEKQLELMT--KPHPEYRLWLTTDPTPTFPIG 3716
+++ +I G+W+ QNCHL S++ LE+ +E + K H ++RLWLT+ P+ FP+
Sbjct: 1482 EAMMRSSIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVS 1541
Query: 3717 ILQRSLK---EPPNGLKLNLRNTYFKMRARALEECPH-PQFKKLVYVLAFFH 3764
ILQ K EPP G++ NL +Y + L C +FK L+ L FH
Sbjct: 1542 ILQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFH 1593
Score = 141 bits (341), Expect = 6e-32
Identities = 95/398 (23%), Positives = 176/398 (44%), Gaps = 17/398 (4%)
Query: 2682 AKCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKIPEEFRPI--IVEHVVHVHMS 2739
A+ R FP LVN TIDW WP +AL +VA VFL ++ ++ I +++ V++H S
Sbjct: 428 ARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGLIQVCVYIHQS 487
Query: 2740 VARYSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANV 2799
V++ E+L L R+NYVTPK Y++ L + L+ +K + R+K GL K+ +
Sbjct: 488 VSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSE 547
Query: 2800 QLEDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAV 2859
+ + L ++ E K+ + +++I T + E++K
Sbjct: 548 DVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQA 607
Query: 2860 EKXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVIIRGIK-- 2917
KND+TE+R+ PP V++V E V I++GIK
Sbjct: 608 IADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPK 667
Query: 2918 -----------DVSWKGAKGMMADP-NFLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLD 2964
D W+ KG++ DP +FL +L + + D I +KA++ ++ + +
Sbjct: 668 KVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAIQPYIDNEEFQPA 727
Query: 2965 TMQQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRL 3024
T+ ++SKA + ++V A+ Y L + + +
Sbjct: 728 TIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLREV 787
Query: 3025 QKTLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKL 3062
+ + + +Y + +++EL+ + + +RL A K+
Sbjct: 788 EDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKV 825
Score = 139 bits (336), Expect = 2e-31
Identities = 78/267 (29%), Positives = 135/267 (50%), Gaps = 5/267 (1%)
Query: 3768 QVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDEYIDF 3827
++ YGG +E++ D P H Y + IPP + Y+ +
Sbjct: 1646 EINYGGRVTDDWDRRCIMNILEDFYNP---DVLSPEHSYSASGIYHQIPPTYDLHGYLSY 1702
Query: 3828 IDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEAGGAMSREDFIDNIAV 3887
I +LPL + PE+FGLH NA I + + G +I+LQP++S AG + RE+ ++++
Sbjct: 1703 IKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSSSAG-SQGREEIVEDVTQ 1761
Query: 3888 DVLSKLPTLYEIWRVRKQFEMNITPTL-VVLLQELERFNRLISRMGSTLSLLRKALAGEI 3946
++L K+P + V ++ + ++ VL+QE+ R+NRL+ + TL L KAL G +
Sbjct: 1762 NILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLV 1821
Query: 3947 GMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTKQYTDWATVEEPVVIW 4006
M + L+ ++ SL+N +P++W A A + K L W+ + R W P V W
Sbjct: 1822 VMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFW 1881
Query: 4007 LSGLHIPESYLIAHVQIACRLYTWPLD 4033
+SG P+++L +Q R + +D
Sbjct: 1882 ISGFFFPQAFLTGTLQNFARKFVISID 1908
Score = 122 bits (293), Expect = 4e-26
Identities = 71/187 (37%), Positives = 102/187 (54%), Gaps = 12/187 (6%)
Query: 2240 PLVDTYGTQQPIALLKLLFERKGFYDRGKDLNWKNLKDIGFLAAMGKAGGGRNDVDPRFI 2299
P ++TYG Q PI LL+ + G+YDR +KNL DI F+ AMG GGGRN V PR +
Sbjct: 2 PALETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLM 61
Query: 2300 SMFSVYNLQFPSENTLRHIYVSIL----------KGHFEIFP--EEIQGIVEKIVQMTLD 2347
F+ + E + + I+ +IL K + E P I E +V+ T+
Sbjct: 62 RHFNYLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIM 121
Query: 2348 LYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMCLTHANYFSEKRTVVRCWRNEFTRVICD 2407
+Y I +L PTPAK HY FNLRDLS++ GM + ++ ++R W +E RV D
Sbjct: 122 VYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRD 181
Query: 2408 RLINQQD 2414
RL+N++D
Sbjct: 182 RLVNEED 188
Score = 118 bits (285), Expect = 3e-25
Identities = 60/174 (34%), Positives = 102/174 (58%), Gaps = 3/174 (1%)
Query: 2499 PMLFGDYRNALDEEEIRYYEDLLDYEAIYFLFQEILDEYNERN-AKMSIVLFEDCLEHLT 2557
P+L+GD+ + +++ YE + + + +E +++YN+ N AK+ +VLF D + H+
Sbjct: 215 PILYGDFMSP--GSDVKSYELITSESKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHIC 272
Query: 2558 RTHRILRMDRGNAMXXXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMKRMY 2617
R R LR GNA+ +LA+ A E F+I +++NY + ++DD+K++
Sbjct: 273 RISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVL 332
Query: 2618 LQLGVDNKKTVFLFTAAQILEEGFLEFINNILMIGMIPALFGDDEKDSIINSVR 2671
L+ G+ N FLF+ QI E FLE INN+L G IP L+ DE+D I++++R
Sbjct: 333 LKAGLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQIVSTMR 386
>AK074130-1|BAB84956.1| 1457|Homo sapiens FLJ00203 protein protein.
Length = 1457
Score = 524 bits (1292), Expect = e-147
Identities = 271/712 (38%), Positives = 419/712 (58%), Gaps = 15/712 (2%)
Query: 3061 KLMSGLSSEQKRWTEDLAALYVEQSRLIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGD 3120
+L++GLS E+ RW E + L + + G+ L+A F++Y GPF+ +R T++Y+ W+
Sbjct: 382 QLINGLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYR-TVLYDSWVKQ 440
Query: 3121 VMERGIPLTLPFTIERNLTNEVEVSGWNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQ 3180
+ +P T T+ L N V++ W GLP D LSV+NG++ + R+ IDPQ+Q
Sbjct: 441 LRSHNVPHTSEPTLIGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQ 500
Query: 3181 ALTWIKKKEAKNNLKVLSFNDPQFLRQLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIK 3240
A WIK E N L V +D FLR +E AI++G P L ++V E +DP ++ VL K
Sbjct: 501 ANKWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTY 560
Query: 3241 VESGRTFVMLGSTEVDYDPNFRMYLTTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLS 3300
+ G T + LG T + Y +FRMY+TTKL NP + P K +IN+T++ GLEDQLL
Sbjct: 561 KQQGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLG 620
Query: 3301 VVVRAERSDLEEQRESLIIETSANKSLLSGLEDSLLRELATSTGNMLDNVELVNTLENTK 3360
VV ER DLEE + LII + + L +ED +L L++S GN +D++EL+ LE +K
Sbjct: 621 QVVAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASK 680
Query: 3361 SKAAEVMEKLELAEATTKDIEKLRDGYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLD 3420
KAAE+ K+ +AE T KDI+ R Y PVA R ILFF +SD+A V+ MYQYSL +L+
Sbjct: 681 MKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLN 740
Query: 3421 VFSFSLRKAMPNVILVKRLKNIIDMLTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDN 3480
+F + + L KR+ NI LT ++Y C +FE+HKL+F+F + +++ +E
Sbjct: 741 IFLSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGK 800
Query: 3481 VSQAQLDFFIK-GNVSLEKSARSSPAP-WMPAQGWQDIMKLSSDFPDPFATLPDDITKFL 3538
++Q++ + + G++S+ +PAP W+ + W+DI+ L S+ P F++ D K L
Sbjct: 801 INQSEWRYLLSGGSISI---MTENPAPDWLSDRAWRDILAL-SNLP-TFSSFSSDFVKHL 855
Query: 3539 EEWQEWFDSDTPESAEIPNNYREKLKPFELLMLLRCFRVDRIYRALTDYITVTMGEEYIT 3598
E++ FDS P +P + + L F+ L++LRC R D++ A+ D++ + +I
Sbjct: 856 SEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIE 915
Query: 3599 PPVISLDMIVEQTTPFTPVVFILSPGSDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAA 3658
P +L ++ + + TP++F+LSPG+DP ADL K A+ F K +SLGQGQ A
Sbjct: 916 PQTANLSVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKF-SKKLSAISLGQGQGPRA 974
Query: 3659 LSLLEGAISHGQWLILQNCHLLVSFLRELEKQLELMT--KPHPEYRLWLTTDPTPTFPIG 3716
+++ +I G+W+ QNCHL S++ LE+ +E + K H ++RLWLT+ P+ FP+
Sbjct: 975 EAMMRSSIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVS 1034
Query: 3717 ILQRSLK---EPPNGLKLNLRNTYFKMRARALEECPH-PQFKKLVYVLAFFH 3764
ILQ K EPP G++ NL +Y + L C +FK L+ L FH
Sbjct: 1035 ILQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFH 1086
Score = 139 bits (336), Expect = 2e-31
Identities = 78/267 (29%), Positives = 135/267 (50%), Gaps = 5/267 (1%)
Query: 3768 QVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDEYIDF 3827
++ YGG +E++ D P H Y + IPP + Y+ +
Sbjct: 1139 EINYGGRVTDDWDRRCIMNILEDFYNP---DVLSPEHSYSASGIYHQIPPTYDLHGYLSY 1195
Query: 3828 IDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEAGGAMSREDFIDNIAV 3887
I +LPL + PE+FGLH NA I + + G +I+LQP++S AG + RE+ ++++
Sbjct: 1196 IKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSSSAG-SQGREEIVEDVTQ 1254
Query: 3888 DVLSKLPTLYEIWRVRKQFEMNITPTL-VVLLQELERFNRLISRMGSTLSLLRKALAGEI 3946
++L K+P + V ++ + ++ VL+QE+ R+NRL+ + TL L KAL G +
Sbjct: 1255 NILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLV 1314
Query: 3947 GMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTKQYTDWATVEEPVVIW 4006
M + L+ ++ SL+N +P++W A A + K L W+ + R W P V W
Sbjct: 1315 VMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFW 1374
Query: 4007 LSGLHIPESYLIAHVQIACRLYTWPLD 4033
+SG P+++L +Q R + +D
Sbjct: 1375 ISGFFFPQAFLTGTLQNFARKFVISID 1401
Score = 74.1 bits (174), Expect = 1e-11
Identities = 61/318 (19%), Positives = 126/318 (39%), Gaps = 15/318 (4%)
Query: 2760 KHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQLEDLNAKLAVQKVIVAEQT 2819
K Y++ L + L+ +K + R+K GL K+ + + + L ++ E
Sbjct: 1 KSYLELLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMHPLLEEAA 60
Query: 2820 KECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVEKXXXXXXXXXXXXXXXXXX 2879
K+ + +++I T + E++K
Sbjct: 61 KDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAAL 120
Query: 2880 XXXXXXXKNDITEIRSFATPPEAVQVVCECVVIIRGIK-------------DVSWKGAKG 2926
KND+TE+R+ PP V++V E V I++GIK D W+ KG
Sbjct: 121 ASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIMKGIKPKKVPGEKPGTKVDDYWEPGKG 180
Query: 2927 MMADP-NFLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLDTMQQISKAGYGLLKFVTAVL 2984
++ DP +FL +L + + D I +KA++ ++ + + T+ ++SKA + ++V A+
Sbjct: 181 LLQDPGHFLESLFKFDKDNIGDVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMH 240
Query: 2985 GYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQKTLDGLNNRYETAMMRRQE 3044
Y L + + ++ + + +Y + +++E
Sbjct: 241 KYHFVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEE 300
Query: 3045 LQEETDLMMRRLVAADKL 3062
L+ + + +RL A K+
Sbjct: 301 LELKCEQCEQRLGRAGKV 318
>AK128592-1|BAC87517.1| 1093|Homo sapiens protein ( Homo sapiens cDNA
FLJ46751 fis, clone TRACH3022960, weakly similar to
Dynein beta chain, ciliary. ).
Length = 1093
Score = 487 bits (1202), Expect = e-136
Identities = 245/657 (37%), Positives = 395/657 (60%), Gaps = 14/657 (2%)
Query: 3123 ERGIPLTLPFTIERNLTNEVEVSGWNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQAL 3182
++ IP + F + + L + V++ WN GLP D S+ NG++ R+PL IDPQ QA
Sbjct: 5 KKKIPCSEEFLLSKTLGDPVKIRAWNIAGLPTDTFSIDNGVIVNNCRRWPLMIDPQGQAN 64
Query: 3183 TWIKKKEAKNNLKVLSFNDPQFLRQLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVE 3242
WIK E +N L V+ +D ++R LE I++G P+L ++V E +DP ++ +L + +
Sbjct: 65 KWIKNSERENQLSVIKLSDSDYMRTLENCIQFGTPLLLENVGEELDPSLEPLLLRQTFKQ 124
Query: 3243 SGRTFVMLGSTEVDYDPNFRMYLTTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVV 3302
G + LG ++Y +F+ Y+TTKL NP + P K ++N+ +T +GLEDQLL +V
Sbjct: 125 GGIDCIRLGEVIIEYSFDFKFYITTKLRNPHYMPELATKVSLLNFMITPEGLEDQLLGIV 184
Query: 3303 VRAERSDLEEQRESLIIETSANKSLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSK 3362
V ER +LEE+R +LI++++ANK L +E +L L++S GN+L++ + L++ K
Sbjct: 185 VAKERPELEEERNALILQSAANKKQLKDIEKKILETLSSSEGNILEDESAIKVLDSAKMM 244
Query: 3363 AAEVMEKLELAEATTKDIEKLRDGYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVF 3422
+ E+ +K ++AE T I + R+GYRP+AK S+LFF ++D+A ++ MYQYSL+ +++++
Sbjct: 245 SNEITKKQQIAEKTELKIAESREGYRPIAKHSSVLFFSIADLANIDPMYQYSLTWFVNLY 304
Query: 3423 SFSLRKAMPNVILVKRLKNIIDMLTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVS 3482
S+ + + IL KRL+ + D T N+Y C +FE+ KLLFSF + L + +
Sbjct: 305 INSIHDSNKSKILEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIE 364
Query: 3483 QAQLDFFIKGNVSLEKSARSSPAP-WMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEW 3541
+L F + G VSL KSA +P P W+ + W++I + +S+FP F L + + EW
Sbjct: 365 YQELMFLLTGGVSL-KSAEKNPDPTWLQDKSWEEICR-ASEFP-AFRGLRQHFCEHIYEW 421
Query: 3542 QEWFDSDTPESAEIPNNYREKLKPFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPV 3601
+E +DS P +A+ P + L + +++LRC R D+I A+T+Y+T +G++++ PP
Sbjct: 422 REIYDSKEPHNAKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPP 481
Query: 3602 ISLDMIVEQTTPFTPVVFILSPGSDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSL 3661
L + P++F+LSPG+DP A L+K A+ G KF+ +SLGQGQ A +
Sbjct: 482 FDLTKSYLDSNCTIPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQGPIAAKM 541
Query: 3662 LEGAISHGQWLILQNCHLLVSFLRELEKQLELMTKP--HPEYRLWLTTDPTPTFPIGILQ 3719
++ AI G W+ LQNCHL VS++ LEK E T + +RLWLT+ P+ FP+ ILQ
Sbjct: 542 IKAAIEEGTWVCLQNCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSKFPVTILQ 601
Query: 3720 RSLK---EPPNGLKLNLRNTYFK---MRARALEECPHPQ--FKKLVYVLAFFHAVVQ 3768
+K EPP GL+LNL +Y + C + ++KL++ + FFHA+VQ
Sbjct: 602 NGVKMTNEPPTGLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQ 658
Score = 215 bits (525), Expect = 3e-54
Identities = 120/389 (30%), Positives = 202/389 (51%), Gaps = 12/389 (3%)
Query: 3771 YGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDEYIDFIDT 3830
YGG T + ++ ++ + P H+ + +Y PP+G ++YI+FI
Sbjct: 710 YGGRVTDDWDRRLLLTMLADFYNLYIVEN--P-HYKFSPSGNYFAPPKGTYEDYIEFIKK 766
Query: 3831 LPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEAGGAMSREDFIDNIAVDVL 3890
LP PE+FGLH N +I Q + ++ L+ Q + + G + S + + I D+L
Sbjct: 767 LPFTQHPEIFGLHENVDISKDLQQTKTLFESLLLTQGGSKQTGASGSTDQILLEITKDIL 826
Query: 3891 SKLPTLYEIWRVRKQFEMNITPTL-VVLLQELERFNRLISRMGSTLSLLRKALAGEIGMD 3949
+KLP+ ++I +++ + ++ VL+QE+ERFN LI + +TL L KA+ G + MD
Sbjct: 827 NKLPSDFDIEMALRKYPVRYEESMNTVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMD 886
Query: 3950 AVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTKQYTDWATVEEPVVIWLSG 4009
+ L+ +S SL G++P++W + + K LG ++ F+AR DW +P V WLSG
Sbjct: 887 SALEALSGSLLVGKVPEIWAKRSYPSLKPLGSYITDFLARLNFLQDWYNSGKPCVFWLSG 946
Query: 4010 LHIPESYLIAHVQIACRLYTWPLDRSTQFTKVTSWVSADEIEERPVTGCYVRGLYLEGAR 4069
+++L +Q R YT P+D +V + +D + P G Y+ GLYL+GAR
Sbjct: 947 FFFTQAFLTGAMQNYARKYTTPIDLLGYEFEV---IPSDTSDTSPEDGVYIHGLYLDGAR 1003
Query: 4070 WDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRTPVYTTSQRRNAM-----GV 4124
WD + G L +PK+L +PI++I P + ++ + P+Y TS+R+ +
Sbjct: 1004 WDRESGLLAEQYPKLLFDLMPIIWIKPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGHST 1063
Query: 4125 GLVFESDLWTTEHCSHWILQGVCLIMNTD 4153
V L T + HWI +GV L+ D
Sbjct: 1064 NFVIAMLLKTDQPTRHWIKRGVALLCQLD 1092
>AJ000522-1|CAA04165.1| 1179|Homo sapiens axonemal dynein heavy chain
protein.
Length = 1179
Score = 442 bits (1090), Expect = e-122
Identities = 250/762 (32%), Positives = 414/762 (54%), Gaps = 23/762 (3%)
Query: 3020 EIDRLQKTLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAA 3079
+I L L L + +E A + + Q+E D R ++ A++L+ GL+SE RW E +
Sbjct: 2 KIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVEN 61
Query: 3080 LYVEQSRLIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIE--RN 3137
+ L G+ LL ++F+SY G F+ +R ++ + W+ + +P+ + ++
Sbjct: 62 FRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSL 121
Query: 3138 LTNEVEVSGWNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVL 3197
LT++ +V+ WN++GLP D +S +N + R+PL +D Q Q + WIK K ++ LK +
Sbjct: 122 LTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKY-RSELKAI 180
Query: 3198 SFNDPQFLRQLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDY 3257
+L +E A G +L +++ E +DP +D +L +N ++ G+ ++ +G EV
Sbjct: 181 RLGQKSYLDVIEQATSEGDTLLIENIGETVDPALDPLLGRNT-IKKGK-YIKIGDKEVGV 238
Query: 3258 DPNFRMYLTTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESL 3317
P T ++ P +IN+ VT GLEDQLL+ VV ER DLE+ + +L
Sbjct: 239 PPQVPPDPTHQVLQPTLQARDAGSVHLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANL 298
Query: 3318 IIETSANKSLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATT 3377
+ K +L LEDSLL L+ ++GN L + LV LE TK A+E+ EK+ A+ T
Sbjct: 299 TKSQNEFKIVLKELEDSLLARLSAASGNFLGDTTLVENLETTKHTASEIEEKVVEAKITE 358
Query: 3378 KDIEKLRDGYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVK 3437
I + R+ YRP A+R S+L+F+L+D+ +N +YQ+SL ++ VF ++++ P + +
Sbjct: 359 VKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQ 418
Query: 3438 RLKNIIDMLTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLE 3497
R+ N+ D +T +VY Y G+FER KL+F Q+ ++ + ++ +LDF ++
Sbjct: 419 RVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPF--- 475
Query: 3498 KSARSSPAPWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPN 3557
K+ SP ++ QGW I LS D F L DI + W++ +S+ PE P
Sbjct: 476 KAGVVSPVDFLQHQGWGGIKALSE--MDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPK 533
Query: 3558 NYREKLKPFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPV 3617
++ K + L ++RC R DR+ A+ +++ MG +++ + E+++P T +
Sbjct: 534 EWKNK-TALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSI 592
Query: 3618 VFILSPGSDPTADLMKLADRCGF--GGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQ 3675
FILSPG DP D+ L + GF GK +SLGQGQE A + L+ A G W+ILQ
Sbjct: 593 FFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQ 652
Query: 3676 NCHLLVSFLRELEKQLE-LMTKPHPEYRLWLTTDPTPT-----FPIGILQRSLK---EPP 3726
N HL+ +L L+K+LE T H +YR+++ +P P+ P GIL+ ++K EPP
Sbjct: 653 NIHLVARWLGTLDKKLERYSTGRHEDYRVFIRAEPAPSPETHIIPQGILENAIKITNEPP 712
Query: 3727 NGLKLNLRNTYFKMRARALEEC-PHPQFKKLVYVLAFFHAVV 3767
G+ NL LE C +FK +++ L +FHAVV
Sbjct: 713 TGMYANLYKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVV 754
Score = 191 bits (466), Expect = 4e-47
Identities = 116/386 (30%), Positives = 192/386 (49%), Gaps = 15/386 (3%)
Query: 3768 QVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDEYIDF 3827
++MYGG TY+ EY+ + + A + IPP + Y ++
Sbjct: 804 EIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLL------APGFQIPPNLDYKGYHEY 857
Query: 3828 IDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSE--AGGAMSREDFIDNI 3885
ID +P ++GLHPNAEIG+ + +++ ++E+QP+ ++ AG +SRE+ + +
Sbjct: 858 IDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAV 917
Query: 3886 AVDVLSKLPTLYEIWRVRKQFEMNITPTLVVLLQELERFNRLISRMGSTLSLLRKALAGE 3945
D+L K+P + + + + TP +VV QE ER N L + M +L L L GE
Sbjct: 918 LDDILEKIPETFNMAEIMAKAAEK-TPYVVVAFQECERMNILTNEMRRSLKELNLGLKGE 976
Query: 3946 IGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTKQYTDWAT-VEEPVV 4004
+ + ++++S +LF +P W A A + GL W + R ++ W T P
Sbjct: 977 LTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTT 1036
Query: 4005 IWLSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVTSWVSADEIEERPVTGCYVRGLY 4064
+WL+G P+S L A +Q R WPLD+ +VT + +++ P G YV GL+
Sbjct: 1037 VWLAGFFNPQSLLTAIMQSMARKNEWPLDKMCLSVEVTK-KNREDMTAPPREGSYVYGLF 1095
Query: 4065 LEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRTPVYTTSQRRNAMGV 4124
+EGARWD G + + K L +P+++I I +++ +N PVY T R G
Sbjct: 1096 MEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVARMETKNIYECPVYKTRIR----GP 1151
Query: 4125 GLVFESDLWTTEHCSHWILQGVCLIM 4150
V+ +L T E + WIL V L++
Sbjct: 1152 TYVWTFNLKTKEKAAKWILAAVALLL 1177
>AB082528-1|BAC02706.2| 1685|Homo sapiens KIAA1997 protein protein.
Length = 1685
Score = 436 bits (1075), Expect = e-121
Identities = 285/1110 (25%), Positives = 538/1110 (48%), Gaps = 31/1110 (2%)
Query: 2673 DSSDAGYGIAKCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKIPEEFRPIIVEH 2732
DS+++ + I C S P L + W W ++ + + ++ E++ +
Sbjct: 161 DSANSNFMI-NCESNPALHKKCQVLWMEGWSNSSMKKIPEMLFSETGG-GEKYNDKKRKE 218
Query: 2733 VVHVHMSVARYSAEFLL--RLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGG 2790
+ + FLL + TP YM FL Y A+ + K ++ + L+ G
Sbjct: 219 EKKKNSVDPDFLKSFLLIHESCKAYGATPSQYMTFLHVYSAISSSKKKELLKRQSHLQAG 278
Query: 2791 LAKIAEANVQLEDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEI 2850
++K+ EA +++LN K Q V++ + E + L+ I+ + + I
Sbjct: 279 VSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRI 338
Query: 2851 TEQSKVIAVEKXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECV 2910
E+ I K ++EIRS PP+ ++ + E V
Sbjct: 339 AEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGV 398
Query: 2911 VIIRGIKDVSWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLD--TMQ 2967
+ + GI D SW K +A ++ + I++ ++V+ + K+K D +
Sbjct: 399 LRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAK 458
Query: 2968 QISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQKT 3027
+ S A L +V A + Y + + L ++ + +
Sbjct: 459 RASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQK 518
Query: 3028 LDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSRL 3087
+ L ++++ +L+ E + AA+ L++ L E KRW + + E + L
Sbjct: 519 VSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATL 578
Query: 3088 IGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSGW 3147
LA +F++Y S R+T + E+W G+ F + R L E E W
Sbjct: 579 PKRAQLAAAFITYLSAAPESLRKTCL-EEW---TKSAGLE---KFDLRRFLCTESEQLIW 631
Query: 3148 NSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLRQ 3207
SEGLP D+LS++N ++ ++ P IDP +QA W+K + L+V++ D F+
Sbjct: 632 KSEGLPSDDLSIENALVILQSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITA 691
Query: 3208 LEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPNFRMYLTT 3267
LE+A+++G ++ Q+++ ++PV+ +L +++ + R V +G +DY+ FR++L+T
Sbjct: 692 LELAVRFGKTLIIQEMDG-VEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLST 750
Query: 3268 KLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANKSL 3327
+ NP P A + +N+T T GL QLL++ ++ E+ DLEEQ+ L+ + K
Sbjct: 751 RNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQ 810
Query: 3328 LSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRDGY 3387
L+ LE+SLL LATS GN+L+N +L+ +L TK+ +A + E L+ + +++ RD Y
Sbjct: 811 LAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAY 870
Query: 3388 RPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDMLT 3447
P+A+ S ++F++SD++ +N+MY++SL+++L +F +L+ + +R++++I L
Sbjct: 871 LPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQ 930
Query: 3448 KNVYDYGCTGIFERHKLLFSFQM------DIKLEQSEDNVSQAQLDFFIKGNVSLEKSAR 3501
VY+Y C +F+ +L+F+ ++ E D + + ++ S +K
Sbjct: 931 HMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRD 990
Query: 3502 SSPAPWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYRE 3561
P+ W+ + + L P + TL + W+ ++++ E E P+ +
Sbjct: 991 QLPS-WIDQERSWAVATLKIALPSLYQTLCFEDAAL---WRTYYNNSMCEQ-EFPSILAK 1045
Query: 3562 KLKPFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFIL 3621
K+ F+ +++++ R DR+ A+ + T+G + ++P ++L + ++T P++ I+
Sbjct: 1046 KVSLFQQILVVQVLRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEIEPILIII 1105
Query: 3622 SPGSDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLV 3681
SPG+DP+ +L +LA+ G + +++GQGQ A+ +L+ +G WL L+N HL+V
Sbjct: 1106 SPGADPSQELQELAN-AERSGECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVV 1164
Query: 3682 SFLRELEKQLELMTKPHPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLNLRNTYF 3738
S+L LEK+L + +P +RLWLT + P F +LQ SLK E P GLK NL TY
Sbjct: 1165 SWLPVLEKELNTL-QPKDTFRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTYE 1223
Query: 3739 KMRARALEECPHPQFKKLVYVLAFFHAVVQ 3768
+ + + ++ LA+FHA Q
Sbjct: 1224 SWTPEQISKKDNTHRAHALFSLAWFHAACQ 1253
Score = 70.5 bits (165), Expect = 1e-10
Identities = 34/136 (25%), Positives = 68/136 (50%)
Query: 2544 MSIVLFEDCLEHLTRTHRILRMDRGNAMXXXXXXXXXXXXCKLAAFAAGCEMFEITVTRN 2603
+ I+LF + LE+++R R+L G+ + L + G +F ++R
Sbjct: 3 LDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRG 62
Query: 2604 YNENTFKDDMKRMYLQLGVDNKKTVFLFTAAQILEEGFLEFINNILMIGMIPALFGDDEK 2663
Y FK+D+K + G++ ++ V L Q + FLE IN++L G +P L+ +E
Sbjct: 63 YELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEEL 122
Query: 2664 DSIINSVRNDSSDAGY 2679
+ ++ +++ +S G+
Sbjct: 123 EPLLLPLKDQASQDGF 138
>AY049075-1|AAL06603.1| 514|Homo sapiens dynein heavy chain protein.
Length = 514
Score = 428 bits (1054), Expect = e-118
Identities = 224/505 (44%), Positives = 308/505 (60%), Gaps = 20/505 (3%)
Query: 1503 TPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDFRAV 1562
TPLTDR Y+T+ QAL M + D+ + LG VV NC + MDFR +
Sbjct: 1 TPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGL 60
Query: 1563 GQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLKRFTVNTDVLKPSQK 1622
G+I GL Q GAWGCFDEFNRID+ VLSV + Q+ I + K F + TD
Sbjct: 61 GRIFKGLAQSGAWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSF-IFTD------- 112
Query: 1623 FGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTELPESVKALFRPVVCILPDLEMICQI 1682
G + M+ + G+F+TMNPGYAGR ELPE++K FR V ++PD ++I ++
Sbjct: 113 ----------GDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRV 162
Query: 1683 SLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTAVLRMAGKLRRDSPGLSE 1742
L S GF+ VLA+K LYK+ EQLSKQ HYD+GLR + +VLR G +R +P +E
Sbjct: 163 KLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTE 222
Query: 1743 IMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEKDGYVV 1802
++MR LRDMN K + ED PLFL LI++LFP + + GYPE AA+ +EK G +
Sbjct: 223 STIVMRVLRDMNLSKLIDEDEPLFLSLIENLFPNILLDKAGYPELEAAINRQVEKAGLIN 282
Query: 1803 LPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNLGLPTKLTVVNPKACS 1862
P KV+Q +T RH M +GP+G GKT +H L++A T+ G P + +NPKA +
Sbjct: 283 HPPWKLKVIQQTKTQRVRHGMMTLGPSGAGKTTCIHTLMRAMTDCGKPHREMRMNPKAIT 342
Query: 1863 VIELYGILDPVTRDWTDGLYSKIFREMNRPAEKNERRYSLFDGDVDALWIENMNSVMDDN 1922
+++G LD T DWTDG++S ++R+ R A+K E + + DG VDA+WIEN+NSV+DDN
Sbjct: 343 APQMFGRLDVATNDWTDGIFSTLWRKTLR-AKKGEHIWIILDGPVDAIWIENLNSVLDDN 401
Query: 1923 KLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGYEPYWERWLSTR 1982
K LTLANG+RI +AP C ++FE +++ ASPATVSR GMVF+ L + P E +L R
Sbjct: 402 KTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPILEGFLKKR 461
Query: 1983 SNEEEREQLSGLFEHYVPGAINYIV 2007
S +E E L L+ P + +
Sbjct: 462 S-PQEAEILRQLYTESFPDLYRFCI 485
>AK023766-1|BAB14671.1| 892|Homo sapiens protein ( Homo sapiens cDNA
FLJ13704 fis, clone PLACE2000274, weakly similar to
DYNEIN BETA CHAIN, CILIARY. ).
Length = 892
Score = 428 bits (1054), Expect = e-118
Identities = 224/584 (38%), Positives = 344/584 (58%), Gaps = 14/584 (2%)
Query: 3189 EAKNNLKVLSFNDPQFLRQLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTFV 3248
E N L V D FLR +E AI++G P L ++V E +DP ++ VL K + G T +
Sbjct: 2 EKDNGLDVFKLGDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQQGSTVL 61
Query: 3249 MLGSTEVDYDPNFRMYLTTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERS 3308
LG T + Y +FRMY+TTKL NP + P K +IN+T++ GLEDQLL VV ER
Sbjct: 62 KLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERP 121
Query: 3309 DLEEQRESLIIETSANKSLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVME 3368
DLEE + LII + + L +ED +L L++S GN +D++EL+ LE +K KAAE+
Sbjct: 122 DLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQA 181
Query: 3369 KLELAEATTKDIEKLRDGYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRK 3428
K+ +AE T KDI+ R Y PVA R ILFF +SD+A V+ MYQYSL +L++F +
Sbjct: 182 KVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIVN 241
Query: 3429 AMPNVILVKRLKNIIDMLTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQLDF 3488
++ L KR+ NI LT ++Y C +FE+HKL+F+F + +++ +E ++Q++ +
Sbjct: 242 SVRADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRY 301
Query: 3489 FIK-GNVSLEKSARSSPAP-WMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFD 3546
+ G++S+ +PAP W+ + W+DI+ L S+ P F++ D K L E++ FD
Sbjct: 302 LLSGGSISI---MTENPAPDWLSDRAWRDILAL-SNLP-TFSSFSSDFVKHLSEFRVIFD 356
Query: 3547 SDTPESAEIPNNYREKLKPFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDM 3606
S P +P + + L F+ L++LRC R D++ A+ D++ + +I P +L +
Sbjct: 357 SLEPHRELLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANLSV 416
Query: 3607 IVEQTTPFTPVVFILSPGSDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAI 3666
+ + + TP++F+LSPG+DP ADL K A+ F K +SLGQGQ A +++ +I
Sbjct: 417 VFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKF-SKKLSAISLGQGQGPRAEAMMRSSI 475
Query: 3667 SHGQWLILQNCHLLVSFLRELEKQLELMT--KPHPEYRLWLTTDPTPTFPIGILQRSLK- 3723
G+W+ QNCHL S++ LE+ +E + K H ++RLWLT+ P+ FP+ ILQ K
Sbjct: 476 ERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKM 535
Query: 3724 --EPPNGLKLNLRNTYFKMRARALEECPH-PQFKKLVYVLAFFH 3764
EPP G++ NL +Y + L C +FK L+ L FH
Sbjct: 536 TIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFH 579
Score = 134 bits (324), Expect = 6e-30
Identities = 74/250 (29%), Positives = 128/250 (51%), Gaps = 5/250 (2%)
Query: 3768 QVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDEYIDF 3827
++ YGG +E++ D P H Y + IPP + Y+ +
Sbjct: 632 EINYGGRVTDDWDRRCIMNILEDFYNP---DVLSPEHSYSASGIYHQIPPTYDLHGYLSY 688
Query: 3828 IDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEAGGAMSREDFIDNIAV 3887
I +LPL + PE+FGLH NA I + + G +I+LQP++S AG + RE+ ++++
Sbjct: 689 IKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSSSAG-SQGREEIVEDVTQ 747
Query: 3888 DVLSKLPTLYEIWRVRKQFEMNITPTL-VVLLQELERFNRLISRMGSTLSLLRKALAGEI 3946
++L K+P + V ++ + ++ VL+QE+ R+NRL+ + TL L KAL G +
Sbjct: 748 NILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLV 807
Query: 3947 GMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTKQYTDWATVEEPVVIW 4006
M + L+ ++ SL+N +P++W A A + K L W+ + R W P V W
Sbjct: 808 VMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFW 867
Query: 4007 LSGLHIPESY 4016
+SG P+++
Sbjct: 868 ISGFFFPQAF 877
>BX538093-1|CAD98012.1| 1732|Homo sapiens hypothetical protein
protein.
Length = 1732
Score = 426 bits (1050), Expect = e-118
Identities = 286/1117 (25%), Positives = 538/1117 (48%), Gaps = 38/1117 (3%)
Query: 2673 DSSDAGYGIAKCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKIPEEFRPIIVEH 2732
DS+++ + I C S P L + W W ++ + + ++ E++ +
Sbjct: 201 DSANSNFMI-NCESNPALHKKCQVLWMEGWSNSSMKKIPEMLFSETGG-GEKYNDKKRKE 258
Query: 2733 VVHVHMSVARYSAEFLL--RLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGG 2790
+ + FLL + TP YM FL Y A+ + K ++ + L+ G
Sbjct: 259 EKKKNSVDPDFLKSFLLIHESCKAYGATPSQYMTFLHVYSAISSSKKKELLKRQSHLQAG 318
Query: 2791 LAKIAEANVQLEDLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEI 2850
++K+ EA +++LN K Q V++ + E + L+ I+ + + I
Sbjct: 319 VSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRI 378
Query: 2851 TEQSKVIAVEKXXXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECV 2910
E+ I K ++EIRS PP+ ++ + E V
Sbjct: 379 AEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGV 438
Query: 2911 VIIRGIKDVSWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMKKSK-KLD--TMQ 2967
+ + GI D SW K +A ++ + I++ ++V+ + K+K D +
Sbjct: 439 LRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAK 498
Query: 2968 QISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQKT 3027
+ S A L +V + Y + + L ++ + +
Sbjct: 499 RASTAAAPLAAWVKVNIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQK 558
Query: 3028 LDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSRL 3087
+ L ++++ +L+ E + AA+ L++ L E KRW + + E + L
Sbjct: 559 VSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATL 618
Query: 3088 IGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSGW 3147
LA +F++Y S R+T + E+W G+ F + R L E E W
Sbjct: 619 PKRAQLAAAFITYLSAAPESLRKTCL-EEW---TKSAGLE---KFDLRRFLCTESEQLIW 671
Query: 3148 NSEGLPPDELSVQNGILTTRA------SRF-PLCIDPQTQALTWIKKKEAKNNLKVLSFN 3200
SEGLP D+LS++N ++ + SR P IDP +QA W+K + L+V++
Sbjct: 672 KSEGLPSDDLSIENALVILQIIGLKSWSRVCPFLIDPSSQATEWLKTHLKDSRLEVINQQ 731
Query: 3201 DPQFLRQLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPN 3260
D F+ LE+A+++G ++ Q+++ ++PV+ +L +++ + R V +G +DY+
Sbjct: 732 DSNFITALELAVRFGKTLIIQEMDG-VEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEE 790
Query: 3261 FRMYLTTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIE 3320
FR++L+T+ NP P A + +N+T T GL QLL++ ++ E+ DLEEQ+ L+ +
Sbjct: 791 FRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQ 850
Query: 3321 TSANKSLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDI 3380
K L+ LE+SLL LATS GN+L+N +L+ +L TK+ +A + E L+ + +
Sbjct: 851 EEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISL 910
Query: 3381 EKLRDGYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLK 3440
++ RD Y P+A+ S ++F++SD++ +N+MY++SL+++L +F +L+ + +R++
Sbjct: 911 DQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQ 970
Query: 3441 NIIDMLTKNVYDYGCTGIFERHKLLFSFQM------DIKLEQSEDNVSQAQLDFFIKGNV 3494
++I L VY+Y C +F+ +L+F+ ++ E D + + ++
Sbjct: 971 SLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKAD 1030
Query: 3495 SLEKSARSSPAPWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAE 3554
S +K P+ W+ + + L P + TL + W+ ++++ E E
Sbjct: 1031 SQQKIRDQLPS-WIDQERSWAVATLKIALPSLYQTLCFEDAAL---WRTYYNNSMCEQ-E 1085
Query: 3555 IPNNYREKLKPFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPF 3614
P+ +K+ F+ +++++ R DR+ A+ + T+G + ++P ++L + ++T
Sbjct: 1086 FPSIPAKKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEI 1145
Query: 3615 TPVVFILSPGSDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLIL 3674
P++ I+SPG+DP+ +L +LA+ G + +++GQGQ A+ +L+ +G WL L
Sbjct: 1146 EPILIIISPGADPSQELQELAN-AERSGECYHQVAMGQGQADLAIQMLKECARNGDWLCL 1204
Query: 3675 QNCHLLVSFLRELEKQLELMTKPHPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKL 3731
+N HL+VS+L LEK+L + +P +RLWLT + P F +LQ SLK E P GLK
Sbjct: 1205 KNLHLVVSWLPVLEKELNTL-QPKDTFRLWLTAEVHPNFTPILLQSSLKITYESPPGLKK 1263
Query: 3732 NLRNTYFKMRARALEECPHPQFKKLVYVLAFFHAVVQ 3768
NL TY + + + ++ LA+FHA Q
Sbjct: 1264 NLMRTYESWTPEQISKKDNTHRAHALFSLAWFHAACQ 1300
Score = 74.9 bits (176), Expect = 6e-12
Identities = 37/146 (25%), Positives = 71/146 (48%)
Query: 2534 LDEYNERNAKMSIVLFEDCLEHLTRTHRILRMDRGNAMXXXXXXXXXXXXCKLAAFAAGC 2593
L Y N + I+LF + LE+++R R+L G+ + L + G
Sbjct: 33 LIHYGRDNQNLDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGA 92
Query: 2594 EMFEITVTRNYNENTFKDDMKRMYLQLGVDNKKTVFLFTAAQILEEGFLEFINNILMIGM 2653
+F ++R Y FK+D+K + G++ ++ V L Q + FLE IN++L G
Sbjct: 93 VLFSPKISRGYELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGE 152
Query: 2654 IPALFGDDEKDSIINSVRNDSSDAGY 2679
+P L+ +E + ++ +++ +S G+
Sbjct: 153 VPGLYTLEELEPLLLPLKDQASQDGF 178
>AK131453-1|BAD18598.1| 1300|Homo sapiens protein ( Homo sapiens cDNA
FLJ16607 fis, clone TESTI4010382, highly similar to
Rattus norvegicus dynein, cytoplasmic, heavy chain 2
(Dnch2). ).
Length = 1300
Score = 397 bits (977), Expect = e-109
Identities = 242/882 (27%), Positives = 455/882 (51%), Gaps = 27/882 (3%)
Query: 2899 PPEAVQVVCECVVIIRGIKDVSWKGAKGMMADPNFLRNLQEMNCDLITQAQVKAVKTHMK 2958
PP+ ++ + E V+ + GI D SW K +A ++ + I++ ++V+ +
Sbjct: 2 PPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEELLF 61
Query: 2959 KSK-KLD--TMQQISKAGYGLLKFVTAVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLA 3015
K+K D ++ S A L +V A + Y + +
Sbjct: 62 KNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKR 121
Query: 3016 SLNREIDRLQKTLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRWTE 3075
L ++ + + + L ++++ +L+ E + AA+ L++ L E KRW
Sbjct: 122 KLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNA 181
Query: 3076 DLAALYVEQSRLIGNCLLATSFLSYTGPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIE 3135
+ + E + L LA +F++Y S R+T + E+W G+ F +
Sbjct: 182 QVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCL-EEW---TKSAGLE---KFDLR 234
Query: 3136 RNLTNEVEVSGWNSEGLPPDELSVQNGILTTRASRFPLCIDPQTQALTWIKKKEAKNNLK 3195
R L E E W SEGLP D+LS++N ++ ++ P IDP +QA W+K + L+
Sbjct: 235 RFLCTESEQLIWKSEGLPSDDLSIENALVILQSRVCPFLIDPSSQATEWLKTHLKDSRLE 294
Query: 3196 VLSFNDPQFLRQLEMAIKYGMPVLFQDVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEV 3255
V++ D F+ LE+A+++G ++ Q+++ ++PV+ +L +++ + R V +G +
Sbjct: 295 VINQQDSNFITALELAVRFGKTLIIQEMDG-VEPVLYPLLRRDLVAQGPRYVVQIGDKII 353
Query: 3256 DYDPNFRMYLTTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRE 3315
DY+ FR++L+T+ NP P A + +N+T T GL QLL++ ++ E+ DLEEQ+
Sbjct: 354 DYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKT 413
Query: 3316 SLIIETSANKSLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEA 3375
L+ + K L+ LE+SLL LATS GN+L+N +L+ +L TK+ +A + E L+ +
Sbjct: 414 KLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYK 473
Query: 3376 TTKDIEKLRDGYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVIL 3435
+++ RD Y P+A+ S ++F++SD++ +N+MY++SL+++L +F +L+ +
Sbjct: 474 LQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENT 533
Query: 3436 VKRLKNIIDMLTKNVYDYGCTGIFERHKLLFSFQM------DIKLEQSEDNVSQAQLDFF 3489
+R++++I L VY+Y C +F+ +L+F+ ++ E D + +
Sbjct: 534 EQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDM 593
Query: 3490 IKGNVSLEKSARSSPAPWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDT 3549
++ S +K P+ W+ + + L P + TL + W+ ++++
Sbjct: 594 LRKADSQQKIRDQLPS-WIDQERSWAVATLKIALPSLYQTLCFEDAAL---WRTYYNNSM 649
Query: 3550 PESAEIPNNYREKLKPFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVE 3609
E E P+ +K+ F+ +++++ R DR+ A+ + T+G + ++P ++L + +
Sbjct: 650 CEQ-EFPSILAKKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYK 708
Query: 3610 QTTPFTPVVFILSPGSDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHG 3669
+T P++ I+SPG+DP+ +L +LA+ G + +++GQGQ A+ +L+ +G
Sbjct: 709 ETLEIEPILIIISPGADPSQELQELAN-AERSGECYHQVAMGQGQADLAIQMLKECARNG 767
Query: 3670 QWLILQNCHLLVSFLRELEKQLELMTKPHPEYRLWLTTDPTPTFPIGILQRSLK---EPP 3726
WL L+N HL+VS+L LEK+L + +P +RLWLT + P F +LQ SLK E P
Sbjct: 768 DWLCLKNLHLVVSWLPVLEKELNTL-QPKDTFRLWLTAEVHPNFTPILLQSSLKITYESP 826
Query: 3727 NGLKLNLRNTYFKMRARALEECPHPQFKKLVYVLAFFHAVVQ 3768
GLK NL TY + + + ++ LA+FHA Q
Sbjct: 827 PGLKKNLMRTYESWTPEQISKKDNTHRAHALFSLAWFHAACQ 868
>AK097746-1|BAC05158.1| 679|Homo sapiens protein ( Homo sapiens cDNA
FLJ40427 fis, clone TESTI2039113. ).
Length = 679
Score = 395 bits (973), Expect = e-108
Identities = 226/686 (32%), Positives = 368/686 (53%), Gaps = 29/686 (4%)
Query: 3488 FFIKGNVSLEKSARSSPAP-WMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFD 3546
F + G VSL KSA +P P W+ + W++I + +S+FP F L + + EW+E +D
Sbjct: 2 FLLTGGVSL-KSAEKNPDPTWLQDKSWEEICR-ASEFP-AFRGLRQHFCEHIYEWREIYD 58
Query: 3547 SDTPESAEIPNNYREKLKPFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDM 3606
S P +A+ P + L + +++LRC R D+I A+T+Y+T +G++++ PP L
Sbjct: 59 SKEPHNAKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTK 118
Query: 3607 IVEQTTPFTPVVFILSPGSDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAI 3666
+ P++F+LSPG+DP A L+K A+ G KF+ +SLGQGQ A +++ AI
Sbjct: 119 SYLDSNCTIPLIFVLSPGADPMASLLKFANDKSMSGNKFQAISLGQGQGPIAAKMIKAAI 178
Query: 3667 SHGQWLILQNCHLLVSFLRELEKQLELMTKP--HPEYRLWLTTDPTPTFPIGILQRSLK- 3723
G W+ LQNCHL VS++ LEK E T + +RLWLT+ P+ FP+ ILQ +K
Sbjct: 179 EEGTWVCLQNCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSKFPVTILQNGVKM 238
Query: 3724 --EPPNGLKLNLRNTYFKMRARALEECPHPQFKKLVYVLAF----FHAVV----QVMYGG 3773
EPP GL+LNL +Y E + K+L+++ + F A+ + YGG
Sbjct: 239 TNEPPTGLRLNLLQSYLTDPVSDPEFFKGCRGKELLFINEYDTIPFEAISYLTGECNYGG 298
Query: 3774 XXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDEYIDFIDTLPL 3833
T + ++ ++ + P H+ + +Y PP+G ++YI+FI LP
Sbjct: 299 RVTDDWDRRLLLTMLADFYNLYIVE--NP-HYKFSPSGNYFAPPKGTYEDYIEFIKKLPF 355
Query: 3834 ANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEAGGAMSREDFIDNIAVDVLSKL 3893
PE+FGLH N +I Q + ++ L+ Q + + G + S + + I D+L+KL
Sbjct: 356 TQHPEIFGLHENVDISKDLQQTKTLFESLLLTQGGSKQTGASGSTDQILLEITKDILNKL 415
Query: 3894 PTLYEIWRVRKQFEMNITPTL-VVLLQELERFNRLISRMGSTLSLLRKALAGEIGMDAVL 3952
P+ ++I +++ + ++ VL+QE+ERFN LI + +TL L KA+ G + MD+ L
Sbjct: 416 PSDFDIEMALRKYPVRYEESMNTVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSAL 475
Query: 3953 DNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTKQYTDWATVEEPVVIWLSGLHI 4012
+ +S SL G++P++W + + K LG ++ F+AR DW +P V WLSG
Sbjct: 476 EALSSSLLVGKVPEIWAKRSYPSLKPLGSYITDFLARLNFLQDWYNSGKPCVFWLSGFFF 535
Query: 4013 PESYLIAHVQIACRLYTWPLDRSTQFTKVTSWVSADEIEERPVTGCYVRGLYLEGARWDV 4072
+++L +Q R YT P+D +V + +D + P G Y+ GLYL+GARWD
Sbjct: 536 TQAFLTGAMQNYARKYTTPIDLLGYEFEV---IPSDTSDTSPEDGVYIHGLYLDGARWDR 592
Query: 4073 DEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRTPVYTTSQRRNAM-----GVGLV 4127
+ G L +PK+L +PI++I P + ++ + P+Y TS+R+ + V
Sbjct: 593 ESGLLAEQYPKLLFDLMPIIWIKPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFV 652
Query: 4128 FESDLWTTEHCSHWILQGVCLIMNTD 4153
L T + HWI +GV L+ D
Sbjct: 653 IAMLLKTDQPTRHWIKRGVALLCQLD 678
>AL096732-1|CAB46377.1| 965|Homo sapiens hypothetical protein
protein.
Length = 965
Score = 356 bits (876), Expect = 8e-97
Identities = 184/533 (34%), Positives = 312/533 (58%), Gaps = 15/533 (2%)
Query: 3247 FVMLGSTEVDYDPNFRMYLTTKLANPQFNPAAYAKAVVINYTVTVQGLEDQLLSVVVRAE 3306
++ LG ++Y +F++Y+TT+L NP + P K ++N+ +T GL+DQLL +V E
Sbjct: 3 YMRLGENIIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKE 62
Query: 3307 RSDLEEQRESLIIETSANKSLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEV 3366
+ +LEE++ LI+E++ NK L +ED +L L+ S GN+L++ + L ++K + E+
Sbjct: 63 KPELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIKVLSSSKVLSEEI 122
Query: 3367 MEKLELAEATTKDIEKLRDGYRPVAKRGSILFFVLSDMAGVNSMYQYSLSSYLDVFSFSL 3426
EK ++A T I++ R GY+PVA + +FF +SD+A + MYQYSL+ +++++ SL
Sbjct: 123 SEKQKVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINLYMHSL 182
Query: 3427 RKAMPNVILVKRLKNIIDMLTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDNVSQAQL 3486
+ + L R+K IID T ++Y+ C +FE+ KLLFS + I + + + +++
Sbjct: 183 THSTKSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVW 242
Query: 3487 DFFIKGNVSLEKSARSSPAP-WMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWF 3545
F + G ++L+ + +PAP W+ + W +I++ S+ P L + + + L EW+ +
Sbjct: 243 YFLLTGGIALD-NPYPNPAPQWLSEKAWAEIVRASA-LP-KLHGLMEHLEQNLGEWKLIY 299
Query: 3546 DSDTPESAEIPNNYREKLKPFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLD 3605
DS P ++P +++ + E +++LRC R D++ A+ ++I MG+ YI P L
Sbjct: 300 DSAWPHEEQLPGSWKFS-QGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQ 358
Query: 3606 MIVEQTTPFTPVVFILSPGSDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGA 3665
++ P++F+LSP +DP A L+K AD G GG + + +SLGQGQ A ++ A
Sbjct: 359 GSYNDSSCCAPLIFVLSPSADPMAGLLKFADDLGMGGTRTQTISLGQGQGPIAAKMINNA 418
Query: 3666 ISHGQWLILQNCHLLVSFLRELEKQLELMTKP---HPEYRLWLTTDPTPTFPIGILQRSL 3722
I G W++LQNCHL S++ LEK E + P + +RLWLT+ P+ FP+ ILQ +
Sbjct: 419 IKDGTWVVLQNCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEKFPVSILQNGI 478
Query: 3723 K---EPPNGLKLNLRNTYFK---MRARALEECPHP-QFKKLVYVLAFFHAVVQ 3768
K EPP GL+ NL +Y + C ++K+++ L FFHAVVQ
Sbjct: 479 KMTNEPPKGLRANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQ 531
Score = 200 bits (487), Expect = 1e-49
Identities = 118/347 (34%), Positives = 182/347 (52%), Gaps = 9/347 (2%)
Query: 3813 YVIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEA 3872
Y IPP G YID++ LP+ PEVFGLH NA+I +Q +++ ++ P+ S
Sbjct: 621 YYIPPHGSYQSYIDYLRNLPITAHPEVFGLHENADITKDNQETNQLFEGVLLTLPRMS-G 679
Query: 3873 GGAMSREDFIDNIAVDVLSKLPTLYEIWRVRKQFEMNITPTL-VVLLQELERFNRLISRM 3931
G S ++ ++ +A D+LSKLP +++ V K + + ++ VL QEL RFNRL +
Sbjct: 680 GSGKSPQEVVEELAQDILSKLPRDFDLEEVMKLYPVVYEESMNTVLRQELIRFNRLTKVV 739
Query: 3932 GSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTK 3991
+L L +A+ G++ M + L+ V S+ G++P +W A + + K LGG++ +AR
Sbjct: 740 RRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARLT 799
Query: 3992 QYTDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVTSWVSADEIE 4051
+ +W PVV W+SG + +S+L Q R YT P+D +VT + +E
Sbjct: 800 FFQEWIDKGPPVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFEVTPQETV--ME 857
Query: 4052 ERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRTP 4111
P G Y++GL+LEGARWD + S PK+L LPI+++ P E Q+ P
Sbjct: 858 NNPEDGAYIKGLFLEGARWDRKTMQIGESLPKILYDPLPIIWLKPGESAMFLHQDIYVCP 917
Query: 4112 VYTTSQRRNAM-----GVGLVFESDLWTTEHCSHWILQGVCLIMNTD 4153
VY TS RR + V +L T HWI +GV + D
Sbjct: 918 VYKTSARRGTLSTTGHSTNYVLSIELPTDMPQKHWINRGVASLCQLD 964
>AC005078-1|AAC78616.2| 1020|Homo sapiens Homo sapiens dynein,
axonemal, heavy polypeptide 11 (DNAH11) protein.
Length = 1020
Score = 319 bits (784), Expect = 1e-85
Identities = 183/506 (36%), Positives = 279/506 (55%), Gaps = 30/506 (5%)
Query: 1668 PVVCILPDLEMICQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTAVL 1727
P + PD+E+IC+I L ++GF+ A+ LA+K LY + +E LSKQ HYDWGLRA+ +VL
Sbjct: 1 PCAMVAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSKQDHYDWGLRAIKSVL 60
Query: 1728 RMAGKLRRDSPGLSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEF 1787
+AG L+R E VLMRALRD N PK V +D+P+FLGL+ DLFP L+ PR F
Sbjct: 61 VVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKLHF 120
Query: 1788 NAAVLEVLEKDGYVVLPHQVDKVVQLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNL 1847
V + + + KVVQL E + RH +VG G GK+ IL L + N+
Sbjct: 121 EQMVRQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYVNM 180
Query: 1848 GLPTKLTVVNPKACSVIELYGILDPVTRDWTD---------GLYSKIFREMNRPAEKNER 1898
+NPKA + EL+G + TR+W D GL+S I RE + +
Sbjct: 181 KQKPVWNDLNPKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFSSILREQAN-LKHDGP 239
Query: 1899 RYSLFDGDVDALWIENMNSVMDDNKLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSR 1958
++ + DGD+D +WIE++N+VMDDNK+LTLA+ ERI L P+ LLFE+ L A+PATVSR
Sbjct: 240 KWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFEIHHLRSATPATVSR 299
Query: 1959 AGMVFVDPKNLGYEPYWERWLSTRSNEEEREQLSGLFEHYVPGAINYIVFGMFGLQQQTP 2018
AG+++V+P++LG+ PY W+ R ++ E+ L+ LF+ YVP ++ + +T
Sbjct: 300 AGILYVNPQDLGWNPYVASWIDRRRHQSEKANLTILFDKYVPACLDKL---------RTS 350
Query: 2019 LKTIVPQTPLNLVMQLCYMISGLLPNNEDTNMEIDKTVVECVFMVSMYNSLGAAIVDNGR 2078
KTI +LV LC ++ LL E+ + K V E F+ + + G ++ +
Sbjct: 351 FKTITSIPESSLVQTLCVLLECLL-TPENVPSDSPKEVYEVYFVFACIWAFGGTLLQDQI 409
Query: 2079 YDFDNYIKKACPMMLVEDNPEKKATTKHFPMGFPTLYDYCLELTTKLWEAWDWLVPEYEH 2138
D+ + +K+ FP T++DY ++ TK W + ++
Sbjct: 410 SDYQADFSRWW---------QKEMKAVKFP-SQGTIFDYYVDHKTKKLLPWADKIAQFTM 459
Query: 2139 DRDMKFPAILVPTVDTLRLTWLIKIM 2164
D D+ +LV T +T RL + ++++
Sbjct: 460 DPDVPLQTVLVHTTETARLRYFMELL 485
Score = 134 bits (323), Expect = 8e-30
Identities = 67/179 (37%), Positives = 103/179 (57%), Gaps = 3/179 (1%)
Query: 2495 VLRDPMLFGDYRNALDEEEIRYYEDLLDYEAIYFLFQEILDEYNERNAKMSIVLFEDCLE 2554
+L+ P++ Y + D + +Y + D+E + + E LD YNE NA M +VLFED ++
Sbjct: 765 LLQQPLI---YCHFADRGKDPHYMPVKDWEVLKTILTETLDNYNELNAAMHLVLFEDAMQ 821
Query: 2555 HLTRTHRILRMDRGNAMXXXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDDMK 2614
H+ R RILR +G A+ +LAA+ G E+F+IT+T Y + D+
Sbjct: 822 HVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLA 881
Query: 2615 RMYLQLGVDNKKTVFLFTAAQILEEGFLEFINNILMIGMIPALFGDDEKDSIINSVRND 2673
+Y++ G N TVFL T AQ+L+E FL IN++L G IP LF D++ D II+ + N+
Sbjct: 882 NLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNE 940
Score = 118 bits (285), Expect = 3e-25
Identities = 80/266 (30%), Positives = 128/266 (48%), Gaps = 28/266 (10%)
Query: 2167 IIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMPIVSHNNQCVP 2226
I+ ++ F+ T+S +Q+ LE +EK+ +GP K+++ FIDDMNM
Sbjct: 518 IVSRVPFNYYTTSTALQKILEKPLEKKAGHNYGPGGNKKLIYFIDDMNM----------- 566
Query: 2227 SLCSTRVQTLLSHPLVDTYGTQQPIALLKLLFERKGFYDRGKDLNWKNLKDIGFLAAMGK 2286
P VD YGT QP L++ + +YDR K + K + + ++A M
Sbjct: 567 -------------PEVDLYGTVQPHTLIRQHIDYGHWYDRQKVM-LKEIHNCQYVACMNP 612
Query: 2287 AGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSILKGHFE--IFPEEIQGIVEKIVQM 2344
G ++PR F+V+ FPS + L IY I HF+ F I ++Q
Sbjct: 613 MVGSFT-INPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQQQAFAPSILRSGPTLIQA 671
Query: 2345 TLDLYKIIIVELPPTPAKFHYIFNLRDLSRIAAGMCLTHANYFSEKRTVVRCWRNEFTRV 2404
T+ ++ ++ PT KFHYIFNLRDLS + G+ ++ W +E RV
Sbjct: 672 TIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASPECLKGPLDLIHLWLHESARV 731
Query: 2405 ICDRLINQQDNELMRGHIQEHVARYF 2430
D+LI+++D +L + + E +YF
Sbjct: 732 YGDKLIDKKDCDLFQRRMLETAYKYF 757
Score = 42.3 bits (95), Expect = 0.036
Identities = 16/39 (41%), Positives = 26/39 (66%)
Query: 2683 KCRSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKI 2721
+ R FP +VN T IDW WP++AL++V+ F+ + + I
Sbjct: 981 RARKFPAIVNCTAIDWFHAWPQEALVSVSRRFIEETKGI 1019
>AK128065-1|BAC87257.1| 821|Homo sapiens protein ( Homo sapiens cDNA
FLJ46185 fis, clone TESTI4004917, moderately similar to
Dynein beta chain, ciliary. ).
Length = 821
Score = 317 bits (778), Expect = 6e-85
Identities = 179/500 (35%), Positives = 281/500 (56%), Gaps = 18/500 (3%)
Query: 3280 AKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANKSLLSGLEDSLLREL 3339
A+ +IN+ VT GLEDQLL+ VV ER DLE+ +L + K +L LEDSLL L
Sbjct: 3 AQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLEANLTKSQNEFKIVLKELEDSLLARL 62
Query: 3340 ATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRDGYRPVAKRGSILFF 3399
+ ++GN L + LV LE TK A+E+ EK+ A+ T I + R+ YRP A+R S+L+F
Sbjct: 63 SAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYF 122
Query: 3400 VLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDMLTKNVYDYGCTGIF 3459
+L+D+ +N +YQ+SL ++ VF ++++ P + +R+ N+ D +T +VY Y G+F
Sbjct: 123 ILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLF 182
Query: 3460 ERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLEKSARSSPAPWMPAQGWQDIMKL 3519
ER KL+F Q+ ++ + ++ +LDF ++ K+ SP ++ QGW I L
Sbjct: 183 ERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPF---KAGVVSPVDFLQHQGWGGIKAL 239
Query: 3520 SSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLKPFELLMLLRCFRVDR 3579
S D F L DI + W++ +S+ PE P ++ K + L ++RC R DR
Sbjct: 240 SE--MDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNK-TALQKLCMVRCLRPDR 296
Query: 3580 IYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPGSDPTADLMKLADRCG 3639
+ A+ +++ MG +++ + E+++P T + FILSPG DP D+ L + G
Sbjct: 297 MTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLG 356
Query: 3640 F--GGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFLRELEKQLE-LMTK 3696
F GK +SLGQGQE A + L+ A G W+ILQN HL+ +L L+K+LE T
Sbjct: 357 FTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQNIHLVARWLGTLDKKLERYSTG 416
Query: 3697 PHPEYRLWLTTDPTPT-----FPIGILQRSLK---EPPNGLKLNLRNTYFKMRARALEEC 3748
H +YR++++ +P P+ P GIL+ ++K EPP G+ NL LE C
Sbjct: 417 SHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMC 476
Query: 3749 -PHPQFKKLVYVLAFFHAVV 3767
+FK +++ L +FHAVV
Sbjct: 477 TKEMEFKCMLFALCYFHAVV 496
Score = 103 bits (246), Expect = 2e-20
Identities = 64/227 (28%), Positives = 112/227 (49%), Gaps = 9/227 (3%)
Query: 3768 QVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDEYIDF 3827
++MYGG TY+ EY+ + + A + IPP + Y ++
Sbjct: 546 EIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLL------APGFQIPPNLDYKGYHEY 599
Query: 3828 IDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSE--AGGAMSREDFIDNI 3885
ID +P ++GLHPNAEIG+ + +++ ++E+QP+ ++ AG +SRE+ + +
Sbjct: 600 IDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAV 659
Query: 3886 AVDVLSKLPTLYEIWRVRKQFEMNITPTLVVLLQELERFNRLISRMGSTLSLLRKALAGE 3945
D+L K+P + + + TP +VV QE ER N L + M +L L L GE
Sbjct: 660 LDDILEKIPETLNMAEIMAKAAEK-TPYVVVAFQECERMNILTNEMRRSLKELNLGLKGE 718
Query: 3946 IGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTKQ 3992
+ + ++++S +LF +P W A A + GL W + R ++
Sbjct: 719 LTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRR 765
>U53530-1|AAB09727.1| 897|Homo sapiens cytoplasmic dynein heavy chain
1 (DHC1) protein.
Length = 897
Score = 306 bits (751), Expect = 1e-81
Identities = 234/847 (27%), Positives = 392/847 (46%), Gaps = 53/847 (6%)
Query: 833 FAKSLEASWGSLYQTSLFRGNTLEQTKEKFSKLNVVEISNFLKELDDFVEKFDNEGPATV 892
+ ++E WG+ + + ++Q V E D + ++ P T
Sbjct: 81 YIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTDWEKTKPVTG 140
Query: 893 EDDMDRGLLLMEEY-GKYIDELESRKKMLQAAE--QLFDNPLADFSNFNRTKADYSAMDQ 949
+ L + Y GK+ + R+K +A E +L D L S R + A+++
Sbjct: 141 NLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSE-ERVQV---ALEE 196
Query: 950 IYKIYKAQKNAREVWAKT------LWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLM 1003
+ + +VW + WV++ P+ L ++ + + P +R ++
Sbjct: 197 LQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASYEF 256
Query: 1004 LDLKMKQFKGVVPLMVSLKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMELHKYQ 1063
+ +K + + L++ LK+EA+++RHWK+LM + ++ +S TL ++ ++L K +
Sbjct: 257 VQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVS--ELTLGQIWDVDLQKNE 314
Query: 1064 DVAEEIVNHAIKELAIERGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVVKLDD 1123
+ ++++ A E+A+E +K ++E W + + N+ + DD+ K+ +
Sbjct: 315 AIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCR----LIRGWDDLFNKVKE 370
Query: 1124 DSMSLQSMAASQFIGPFLTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGG-DIRT 1182
S+ +M S + F +WE +L+ I + + W+ QR+W+YLEGIF G DI+
Sbjct: 371 HINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKH 430
Query: 1183 QLPEEAKKFDDIDRAFRKIMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASS 1242
LP E ++F I F +M +K V+D I G L L KI ++
Sbjct: 431 LLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLL--GKIQKALGE 488
Query: 1243 DVTRKQINLSQAIAWADRASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYVDHT 1302
+ R++ + + D L ++ S AK Q + MF + ++ L D++
Sbjct: 489 YLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKH------FKKMFAGVSSIILNEDNS 542
Query: 1303 NRPVAAKMISAEGEIMDFRNVV-YTEG-RVEDWMNLVLVEMRHT-NKFITKKA--IFYYG 1357
V + S EGE + F+ V TE ++ +W+ LV EMR T K + + + +G
Sbjct: 543 ---VVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFG 599
Query: 1358 KNWKV-PRT--DWILEYQGMVCLAANGVWWTAETEETFLRIKKGNKRAMKEHLQQQNE-Q 1413
K + P T WI +YQ + + + + W+ E + G A + + E
Sbjct: 600 KATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPSDSVLSNVEVT 659
Query: 1414 LDGLVVKVRQDLSSNDRLKFRTITTIDVHARDIIEGFVRDNITEAAEFEWESQLRFYWLK 1473
L+ L V + R K + T VH RD+ ++ I A FEW SQ+RFY+
Sbjct: 660 LNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDP 719
Query: 1474 KDDN----LWIRQCTGVFEYGYEYMGLNGRLVITPLTDRIYLTITQALTMQLXXXXXXXX 1529
K + L I+ F YG+EY+G+ +LV TPLTDR YLT+TQAL +L
Sbjct: 720 KQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPA 779
Query: 1530 XXXXXXXXXDLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVL 1589
L LG +V NC E DF+A G+I GLCQ GAWGCFDEFNR++ +L
Sbjct: 780 GTGKTESVKALGHQLGRFVLVFNCDETFDFQARGRIFVGLCQVGAWGCFDEFNRLEERML 839
Query: 1590 SVISTQLQCIRSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMN 1649
S +S Q+QCI+ AL R N + K S T +++ + + IFITMN
Sbjct: 840 SAVSQQVQCIQEAL-----REHSNPNYDKTSAPI----TCELLNKQVKVSPDMAIFITMN 890
Query: 1650 PGYAGRT 1656
PGYAG +
Sbjct: 891 PGYAGNS 897
>BC019878-1|AAH19878.1| 314|Homo sapiens DNAH3 protein protein.
Length = 314
Score = 246 bits (603), Expect = 1e-63
Identities = 124/305 (40%), Positives = 192/305 (62%), Gaps = 8/305 (2%)
Query: 1692 AKVLAKKMTVLYKVAREQLSKQSHYDWGLRALTAVLRMAGKLRRDSPGLSEIMVLMRALR 1751
++ LA+K+ Y++ EQLS Q HYD+G+RA+ +VL AG L+ P +E ++L+RAL
Sbjct: 2 SRSLAQKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALL 61
Query: 1752 DMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEKDGYVVLPHQVDKVV 1811
D+N KF+ +DVPLF G+I DLFPG+ P+ Y F + + ++K +P + K++
Sbjct: 62 DVNLAKFLAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKKMKLQPVPWFIGKII 121
Query: 1812 QLYETMMTRHCTMLVGPTGGGKTVILHCLVKAQTNLGLPTKL-------TVVNPKACSVI 1864
Q+YE M+ RH M+VG GGKT L A +L ++ ++NPKA ++
Sbjct: 122 QIYEMMLVRHGYMIVGDPMGGKTSAYKVLAAALGDLHAANQMEEFAVEYKIINPKAITMG 181
Query: 1865 ELYGILDPVTRDWTDGLYSKIFREMNRPAEKNERRYSLFDGDVDALWIENMNSVMDDNKL 1924
+LYG D V+ +W DG+ + FRE + ++R++ +FDG VDA+WIENMN+V+DDNK
Sbjct: 182 QLYGCFDQVSHEWMDGVLANAFRE-QASSLSDDRKWIIFDGPVDAIWIENMNTVLDDNKK 240
Query: 1925 LTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVFVDPKNLGYEPYWERWLSTRSN 1984
L L +GE I++ SL+FE DL ASPATVSR GM++++P LG++P + ++ T +
Sbjct: 241 LCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGMIYMEPHQLGWKPLKDSYMDTLPS 300
Query: 1985 EEERE 1989
+E
Sbjct: 301 SLTKE 305
>X99947-1|CAA68207.1| 798|Homo sapiens dynein-related protein
protein.
Length = 798
Score = 226 bits (553), Expect = 1e-57
Identities = 127/379 (33%), Positives = 210/379 (55%), Gaps = 18/379 (4%)
Query: 3401 LSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDMLTKNVYDYGCTGIFE 3460
++D++ ++ MYQ+SL ++ VF ++ +A P+ L +R+ N+ID +T +VY Y G+FE
Sbjct: 1 MNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFE 60
Query: 3461 RHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLEKSARSSPAPWMPAQGWQDIMKLS 3520
KL + Q+ ++ V+ +LDF ++ V ++ +SP ++ Q W + LS
Sbjct: 61 CDKLTYLAQLTFQILLMNREVNAVELDFLLRSPV---QTGTASPVEFLSHQAWGAVKVLS 117
Query: 3521 SDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLKPFELLMLLRCFRVDRI 3580
S + F+ L DI + W+++ +S+ PE ++P ++ K + L +LR R DR+
Sbjct: 118 S--MEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNK-TALQRLCMLRAMRPDRM 174
Query: 3581 YRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPGSDPTADLMKLADRCG- 3639
AL D++ +G +Y+ + E++ P TP+ FILSPG DP D+ + G
Sbjct: 175 TYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGY 234
Query: 3640 -FGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFLRELEKQLELMTK-P 3697
F F +SLGQGQE A + L+ A G W+ILQN HL+ +L LEK+LE ++
Sbjct: 235 TFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHSENS 294
Query: 3698 HPEYRLWLTTDPTPT-----FPIGILQRSLK---EPPNGLKLNLRNTYFKMRARALEECP 3749
HPE+R++++ +P P+ P GIL+ S+K EPP G+ NL LE C
Sbjct: 295 HPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCS 354
Query: 3750 -HPQFKKLVYVLAFFHAVV 3767
+FK +++ L +FHAVV
Sbjct: 355 RETEFKSILFALCYFHAVV 373
Score = 179 bits (435), Expect = 2e-43
Identities = 114/386 (29%), Positives = 187/386 (48%), Gaps = 15/386 (3%)
Query: 3768 QVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDEYIDF 3827
++MYGG TY+ GEF+ + A + +P + + Y +
Sbjct: 423 EIMYGGHITDDWDRRLCRTYL----GEFIRPEMLEGEL--SLAPGFPLPGNMDYNGYHQY 476
Query: 3828 IDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEA--GGAMSREDFIDNI 3885
ID +P ++GLHPNAEIG+ +Q +++ ++ELQP+ S+A G +RE+ + +
Sbjct: 477 IDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKAL 536
Query: 3886 AVDVLSKLPTLYEIWRVRKQFEMNITPTLVVLLQELERFNRLISRMGSTLSLLRKALAGE 3945
++L ++ + I + + E TP +VV QE R N L + +L L L GE
Sbjct: 537 LEEILERVTDEFNIPELMAKVEER-TPYIVVAFQECGRMNILTREIQRSLRELELGLKGE 595
Query: 3946 IGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTKQYTDWA-TVEEPVV 4004
+ M + ++N+ +L+ +P+ W A + GL + R K+ W P
Sbjct: 596 LTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAARFPDLLNRIKELEAWTGDFTIPST 655
Query: 4005 IWLSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVTSWVSADEIEERPVTGCYVRGLY 4064
+WL+G P+S+L A +Q R WPLD+ +T + +E P G Y+ GL+
Sbjct: 656 VWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTK-KNREEFRSPPREGAYIHGLF 714
Query: 4065 LEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRTPVYTTSQRRNAMGV 4124
+EGA WD G + + K L +P+M+I I K ++ PVY TSQR G
Sbjct: 715 MEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQR----GP 770
Query: 4125 GLVFESDLWTTEHCSHWILQGVCLIM 4150
V+ +L T E+ S W+L GV L++
Sbjct: 771 TYVWTFNLKTKENPSKWVLAGVALLL 796
>BC128421-1|AAI28422.1| 798|Homo sapiens DNAH9 protein protein.
Length = 798
Score = 226 bits (553), Expect = 1e-57
Identities = 127/379 (33%), Positives = 210/379 (55%), Gaps = 18/379 (4%)
Query: 3401 LSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDMLTKNVYDYGCTGIFE 3460
++D++ ++ MYQ+SL ++ VF ++ +A P+ L +R+ N+ID +T +VY Y G+FE
Sbjct: 1 MNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFE 60
Query: 3461 RHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLEKSARSSPAPWMPAQGWQDIMKLS 3520
KL + Q+ ++ V+ +LDF ++ V ++ +SP ++ Q W + LS
Sbjct: 61 CDKLTYLAQLTFQILLMNREVNAVELDFLLRSPV---QTGTASPVEFLSHQAWGAVKVLS 117
Query: 3521 SDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLKPFELLMLLRCFRVDRI 3580
S + F+ L DI + W+++ +S+ PE ++P ++ K + L +LR R DR+
Sbjct: 118 S--MEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNK-TALQRLCMLRAMRPDRM 174
Query: 3581 YRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPGSDPTADLMKLADRCG- 3639
AL D++ +G +Y+ + E++ P TP+ FILSPG DP D+ + G
Sbjct: 175 TYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGY 234
Query: 3640 -FGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFLRELEKQLELMTK-P 3697
F F +SLGQGQE A + L+ A G W+ILQN HL+ +L LEK+LE ++
Sbjct: 235 TFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHSENS 294
Query: 3698 HPEYRLWLTTDPTPT-----FPIGILQRSLK---EPPNGLKLNLRNTYFKMRARALEECP 3749
HPE+R++++ +P P+ P GIL+ S+K EPP G+ NL LE C
Sbjct: 295 HPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCS 354
Query: 3750 -HPQFKKLVYVLAFFHAVV 3767
+FK +++ L +FHAVV
Sbjct: 355 RETEFKSILFALCYFHAVV 373
Score = 185 bits (450), Expect = 3e-45
Identities = 115/386 (29%), Positives = 188/386 (48%), Gaps = 15/386 (3%)
Query: 3768 QVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDEYIDF 3827
++MYGG TY+ GEF+ + A + +P + + Y +
Sbjct: 423 EIMYGGHITDDWDRRLCRTYL----GEFIRPEMLEGEL--SLAPGFPLPGNMDYNGYHQY 476
Query: 3828 IDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEA--GGAMSREDFIDNI 3885
ID +P ++GLHPNAEIG+ +Q +++ ++ELQP+ S+A G +RE+ + +
Sbjct: 477 IDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKAL 536
Query: 3886 AVDVLSKLPTLYEIWRVRKQFEMNITPTLVVLLQELERFNRLISRMGSTLSLLRKALAGE 3945
++L ++ + I + + E TP +VV QE R N L + +L L L GE
Sbjct: 537 LEEILERVTDEFNIPELMAKVEER-TPYIVVAFQECGRMNILTREIQRSLRELELGLKGE 595
Query: 3946 IGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTKQYTDWA-TVEEPVV 4004
+ M + ++N+ +L+ +P+ W A + GL W + R K+ W P
Sbjct: 596 LTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPST 655
Query: 4005 IWLSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVTSWVSADEIEERPVTGCYVRGLY 4064
+WL+G P+S+L A +Q R WPLD+ +T + +E P G Y+ GL+
Sbjct: 656 VWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTK-KNREEFRSPPREGAYIHGLF 714
Query: 4065 LEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRTPVYTTSQRRNAMGV 4124
+EGA WD G + + K L +P+M+I I K ++ PVY TSQR G
Sbjct: 715 MEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQR----GP 770
Query: 4125 GLVFESDLWTTEHCSHWILQGVCLIM 4150
V+ +L T E+ S W+L GV L++
Sbjct: 771 TYVWTFNLKTKENPSKWVLAGVALLL 796
>BC128261-1|AAI28262.1| 798|Homo sapiens DNAH9 protein protein.
Length = 798
Score = 226 bits (553), Expect = 1e-57
Identities = 127/379 (33%), Positives = 210/379 (55%), Gaps = 18/379 (4%)
Query: 3401 LSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDMLTKNVYDYGCTGIFE 3460
++D++ ++ MYQ+SL ++ VF ++ +A P+ L +R+ N+ID +T +VY Y G+FE
Sbjct: 1 MNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFE 60
Query: 3461 RHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLEKSARSSPAPWMPAQGWQDIMKLS 3520
KL + Q+ ++ V+ +LDF ++ V ++ +SP ++ Q W + LS
Sbjct: 61 CDKLTYLAQLTFQILLMNREVNAVELDFLLRSPV---QTGTASPVEFLSHQAWGAVKVLS 117
Query: 3521 SDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLKPFELLMLLRCFRVDRI 3580
S + F+ L DI + W+++ +S+ PE ++P ++ K + L +LR R DR+
Sbjct: 118 S--MEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNK-TALQRLCMLRAMRPDRM 174
Query: 3581 YRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPGSDPTADLMKLADRCG- 3639
AL D++ +G +Y+ + E++ P TP+ FILSPG DP D+ + G
Sbjct: 175 TYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGY 234
Query: 3640 -FGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFLRELEKQLELMTK-P 3697
F F +SLGQGQE A + L+ A G W+ILQN HL+ +L LEK+LE ++
Sbjct: 235 TFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHSENS 294
Query: 3698 HPEYRLWLTTDPTPT-----FPIGILQRSLK---EPPNGLKLNLRNTYFKMRARALEECP 3749
HPE+R++++ +P P+ P GIL+ S+K EPP G+ NL LE C
Sbjct: 295 HPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCS 354
Query: 3750 -HPQFKKLVYVLAFFHAVV 3767
+FK +++ L +FHAVV
Sbjct: 355 RETEFKSILFALCYFHAVV 373
Score = 184 bits (449), Expect = 5e-45
Identities = 115/386 (29%), Positives = 188/386 (48%), Gaps = 15/386 (3%)
Query: 3768 QVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDEYIDF 3827
++MYGG TY+ GEF+ + A + +P + + Y +
Sbjct: 423 EIMYGGHITDDWDRRLCRTYL----GEFIRPEMLEGEL--SLAPGFPLPGNMDYNGYHQY 476
Query: 3828 IDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEA--GGAMSREDFIDNI 3885
ID +P ++GLHPNAEIG+ +Q +++ ++ELQP+ S+A G +RE+ + +
Sbjct: 477 IDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKAL 536
Query: 3886 AVDVLSKLPTLYEIWRVRKQFEMNITPTLVVLLQELERFNRLISRMGSTLSLLRKALAGE 3945
++L ++ + I + + E TP +VV QE R N L + +L L L GE
Sbjct: 537 LEEILERVTDEFNIPELMAKVEER-TPYIVVAFQECGRMNILTREIQRSLRELELGLKGE 595
Query: 3946 IGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTKQYTDWA-TVEEPVV 4004
+ M + ++N+ +L+ +P+ W A + GL W + R K+ W P
Sbjct: 596 LTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPST 655
Query: 4005 IWLSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVTSWVSADEIEERPVTGCYVRGLY 4064
+WL+G P+S+L A +Q R WPLD+ +T + +E P G Y+ GL+
Sbjct: 656 VWLTGFFNPQSFLTAIMQSTARKNEWPLDQIALQCDMTK-KNREEFRSPPREGAYIHGLF 714
Query: 4065 LEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRTPVYTTSQRRNAMGV 4124
+EGA WD G + + K L +P+M+I I K ++ PVY TSQR G
Sbjct: 715 MEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQR----GP 770
Query: 4125 GLVFESDLWTTEHCSHWILQGVCLIM 4150
V+ +L T E+ S W+L GV L++
Sbjct: 771 TYVWTFNLKTKENPSKWVLAGVALLL 796
>AC104600-1|AAY24051.1| 1270|Homo sapiens unknown protein.
Length = 1270
Score = 226 bits (553), Expect = 1e-57
Identities = 163/656 (24%), Positives = 307/656 (46%), Gaps = 32/656 (4%)
Query: 824 INVTDEDLQFAKSLEASWGSLYQTSLFRGNTLEQTKEKFSKLNVVEISNFLKELDDFVEK 883
+N + D++ S+ +G + + +++ E++ + + F++EL+ + ++
Sbjct: 638 VNFSPADMRLNNSVFQWYGRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQ 697
Query: 884 FDNEGPATVEDDMDRGLLLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNFNRTKAD 943
+ D+ R L + +D + + A E+ F + + + +
Sbjct: 698 SEEFYSFGDLQDVQRYLKKAQILNGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDG 757
Query: 944 YSAMDQIYKIYKAQKNAREVWAKTLWVNLNPQALVDGIEQFFKEYRKLPKIVRLSSTGLM 1003
+ ++Y+ + W + + +NP + I +++ KL K S L
Sbjct: 758 LNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALA 817
Query: 1004 LDLKMKQ----FKGVVPLMVSLKNEAMRERHWKELMAKTGQDFDMSPDRFTLENMFAMEL 1059
+ K++ FK +PL+ + N +R RHW+ + A G S D T+ + M L
Sbjct: 818 MTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDS-TVSSFLDMNL 876
Query: 1060 HKYQDVAEEIVNHAIKELAIERGVKDVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVV 1119
Y D E I A KE ++E+ ++ + W + F + + G + L D+I +
Sbjct: 877 EPYIDRFEGISEAASKEYSLEKAMEKMITEWDAVEFVIHSYRETGT---FILASVDEIQM 933
Query: 1120 KLDDDSMSLQSMAASQFIGPFLTVVQTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGGD 1179
LDD + Q+M S FI P+ ++ WE +L L+ EI++EW+ Q WLYLE IF D
Sbjct: 934 LLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIFSSPD 993
Query: 1180 IRTQLPEEAKKFDDIDRAFRKIMLDTAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRS 1239
I +Q+PEE ++F +D+ +R IM + +V+ TI LE L+ I++
Sbjct: 994 IMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLE--LILKG 1051
Query: 1240 ASSDVTRKQINLSQAIAWADRASLSLVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYV 1299
+ + +K++ + ++ L ++ + + Q ++ F+ I V
Sbjct: 1052 LNEYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPH------LKKCFEGIAK----V 1101
Query: 1300 DHTNRPVAAKMISAEGEIMDFRNVVYT---EGRVEDWM-NLVLVEMRHTNKFITKKAIFY 1355
+ T M S+EGE+++ ++ T G+VE W+ L V + +K +T A F
Sbjct: 1102 EFTETLDITHMKSSEGEVVELIEIISTAKARGQVEKWLVELERVMINSIHK-VTGDATFA 1160
Query: 1356 YGKNWKVPRTDWILEYQGMVCLAANGVWWTAETEETFLRIKKGNKRAMKEHLQQQNEQLD 1415
Y K R +W+ ++ G L + ++WT E + I G K A++++L+ N Q+D
Sbjct: 1161 Y---TKYERINWVRDWPGQTVLCVSQIFWTKEVQTA---IPMGIK-ALEQYLKTCNRQID 1213
Query: 1416 GLVVKVRQDLSSNDRLKFRTITTIDVHARDIIEGFVRDNITEAAEFEWESQLRFYW 1471
+V VR LS +R+ + +DVHARD++ V+ NI++ ++FEW SQLR+YW
Sbjct: 1214 DIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDSDFEWLSQLRYYW 1269
>AL162738-2|CAI95642.2| 582|Homo sapiens novel protein protein.
Length = 582
Score = 226 bits (552), Expect = 2e-57
Identities = 147/584 (25%), Positives = 270/584 (46%), Gaps = 6/584 (1%)
Query: 2685 RSFPGLVNNTTIDWQFPWPKQALLAVANVFLADVQKIP--EEFRPIIVEHVVHVHMSVAR 2742
R +P ++++ TIDW WP++ALL VAN FL + E + + V +H S+
Sbjct: 1 RVYPSMISSCTIDWYERWPEEALLIVANSFLKEKVNFENRENLKEKLAPTCVQIHKSMKD 60
Query: 2743 YSAEFLLRLRRNNYVTPKHYMDFLTNYLALLNEKDAFIVAQCERLKGGLAKIAEANVQLE 2802
+ ++ R Y TP Y+ F+ + +L ++ + + +R GL+ I EA +
Sbjct: 61 LNRKYFEETGRFYYTTPNSYLQFMETFAHILRAREEEMQTKRDRFHMGLSTILEATTLVT 120
Query: 2803 DLNAKLAVQKVIVAEQTKECEILLKEISTATEXXXXXXXXXXXXXXEITEQSKVIAVEKX 2862
++ +L + V ++TKE E L++++ ++ + E+ +++
Sbjct: 121 EMQEELLILGPQVEQKTKETETLMEKLRKDSQVVEKVQMLVKQDEEIVAEEVRIVEDYAQ 180
Query: 2863 XXXXXXXXXXXXXXXXXXXXXXXXKNDITEIRSFATPPEAVQVVCECVVIIRGIKDVSWK 2922
K D+ E+R + PP V V V I+ K +W
Sbjct: 181 KTANELKSVLPAFDKAIVALNALDKADVAELRVYTRPPFLVLTVMNAVCILLQ-KKPNWA 239
Query: 2923 GAKGMMADPNFLRNLQEMNCDLIT-QAQVKAVKTHMKKSKKLDTMQQISKAGYGLLKFVT 2981
AK ++++ FL+ L ++ D I + VK K + +S A L ++V
Sbjct: 240 TAKLLLSETGFLKKLINLDKDSIPDKVFVKLKKIVTLPDFNPHKISLVSVACCSLCQWVI 299
Query: 2982 AVLGYCAXXXXXXXXXXXXXXXXXXYSEAVNYLASLNREIDRLQKTLDGLNNRYETAMMR 3041
A+ Y A LA R + +++ L L Y+ +
Sbjct: 300 ALNNYHEVQKVVGPKQIQVAEAQNVLKIARQRLAEKQRGLQLVEEHLLFLQAAYKDTVAE 359
Query: 3042 RQELQEETDLMMRRLVAADKLMSGLSSEQKRWTEDLAALYVEQSRLIGNCLLATSFLSYT 3101
+Q L + RR A L++ L E+ RW E + + + ++G+ LL+ + + Y+
Sbjct: 360 KQLLANRKTMASRRFQCASVLLTVLEDEKTRWQETINQIDNKLEGILGDILLSAACIVYS 419
Query: 3102 GPFSFSFRQTMIYEDWLGDVMERGIPLTLPFTIERNLTNEVEVSGWNSEGLPPDELSVQN 3161
G + FRQ +I W +E GI L+ F++ + + + E+S W+++GLP + SV+N
Sbjct: 420 GILTPEFRQ-LIVNKWETFCIENGISLSSKFSLIKVMAQKYEISRWHNQGLPHGQYSVEN 478
Query: 3162 GILTTRASRFPLCIDPQTQALTWIKKKEAKNNLKVLSFNDPQFLRQLEMAIKYGMPVLFQ 3221
IL ++PL IDP QA WI++ E + L+ LS D + +++E A+K G VL Q
Sbjct: 479 AILIKNGQQWPLLIDPHRQAHKWIRQMEG-SRLQKLSIEDSNYTKKIENAMKTGGSVLLQ 537
Query: 3222 DVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPNFRMYL 3265
++ E + P + +L+K+I + G F+ +G E +Y+ NFR+++
Sbjct: 538 NLLETLAPGLKAILKKDIYQKKGHYFIRVGDAEFEYNSNFRIHI 581
>AK125475-1|BAC86173.1| 913|Homo sapiens protein ( Homo sapiens
cDNA FLJ43486 fis, clone OCBBF3003592, weakly similar
to Dynein beta chain, flagellar outer arm. ).
Length = 913
Score = 223 bits (545), Expect = 1e-56
Identities = 115/390 (29%), Positives = 204/390 (52%), Gaps = 13/390 (3%)
Query: 375 FQPNFDKDLFLVIHEAELMEQLGFDVPSNVRDVAMQKSRLFYELEALSKIIAKYNKNASS 434
F NF L +I+E + +EQLGF VP R+VA+Q+ + + +++ Y+ +
Sbjct: 480 FAINFSPALREIINETKYLEQLGFTVPELARNVALQEDKFLRYTAGIQRMLDHYHMLIGT 539
Query: 435 LSPSETYLMKRHLLDMERHILPGLTRITWTALGINDYIKDITKGENSLQAVYQQLKMVEK 494
L+ +E+ L+K H ++ R G R+ W +LGI DYI + +++ Q+
Sbjct: 540 LNDAESVLLKDHSQELLRVFRSGYKRLNWNSLGIGDYITGCKQAIGKFESLVHQIHKNAD 599
Query: 495 EIQFLINQLQEFDLFPVVRPKNYKDPETGIPDDTWIYPCKTYFVEVENERLERVAGLSRI 554
+I + ++ +LF K+ E +P K +F +E ER V + R
Sbjct: 600 DISSRLTLIEAINLFKYPAAKS----EEELPG------VKEFFEHIERERASDVDHMVRW 649
Query: 555 YDRIGPILMKLEYLILGTSSGRSEVMASYYAYWEKKIFKCLVNFTLENLEHFQQMLSEKT 614
Y IGP+L K+E L++ T++G++ +ASYY YWEKKI++ L L+NL+ F ++
Sbjct: 650 YLAIGPLLTKVEGLVVHTNTGKAPKLASYYKYWEKKIYEVLTKLILKNLQSFNSLILGNV 709
Query: 615 PLFQVDAVLVPPDITMRPTSSEVCNILGYNIKHFLNRLTAFPRWMKKTCLPCPPQRVAEA 674
PLF + +L P+I + P ++E+ + + +++ + F RWM +C+ CPPQ+ E
Sbjct: 710 PLFHTETILTAPEIILHPNTNEIDKMCFHCVRNCVEITKHFVRWMNGSCIECPPQKGEE- 768
Query: 675 TGNEYYVFSYFEDILRVVAINDITLLIQDTIYRLTQDINSYIQKWHKYQHLWAFDKSLSC 734
E + +++ DI I + ++I ++R+ ++ Y+QKW +Y+ LW DK++
Sbjct: 769 --EEVVIINFYNDISLNPQIIEQAVMIPQNVHRILINLMKYLQKWKRYRPLWKLDKAIVM 826
Query: 735 EKYIQKHEQIYKYDEKFFFFEDIISDLNTH 764
EK+ K YDEK F+ I ++ H
Sbjct: 827 EKFAAKKPPCVAYDEKLQFYSKIAYEVMRH 856
Score = 110 bits (265), Expect = 9e-23
Identities = 51/112 (45%), Positives = 70/112 (62%)
Query: 1 MWHDLYKETRRNIELSGKGARWEFDQPLLFTRTDYIGTVARDLGDIIQVLIDFERIFGLE 60
+W Y +TR IE SG+ RWEFD+ LF RTDY+ T+ +DL D++QVL +F IFG E
Sbjct: 250 LWKKAYFDTRAKIEASGREDRWEFDRKRLFERTDYMATICQDLSDVLQVLEEFYNIFGPE 309
Query: 61 LKSIISDPTQIDDVRKRVKNLVYPIRTVDFSVFVFDNKENWDVIMGDFWNEV 112
LK++ DP +IDDV RV LV P+ + F F + + W +M +F EV
Sbjct: 310 LKAVTGDPKRIDDVLCRVDGLVTPMENLTFDPFSIKSSQFWKYVMDEFKIEV 361
Score = 91.9 bits (218), Expect = 4e-17
Identities = 51/137 (37%), Positives = 81/137 (59%), Gaps = 5/137 (3%)
Query: 135 EALTVLLKFLEFDTRESIRRQLSTKFDLVMRQFIKE--ITAIEDKFTRYRKNPPLLRNHP 192
+ L ++ L FD SI+ K+ VM +F E I I F + +NPPL +NHP
Sbjct: 328 DGLVTPMENLTFDPF-SIKSSQFWKY--VMDEFKIEVLIDIINKIFVQNLENPPLYKNHP 384
Query: 193 PVAGAISWARALFNKMKQPIMKFQKVSELNECEQKKEAFLQYKAFSKIIKEYEDTKYKEW 252
PVAGAI W R+LF ++K I++FQ+V E+ + ++ +E +Y + +KEYED KY++W
Sbjct: 385 PVAGAIYWERSLFFRIKHTILRFQEVQEILDSDRGQEVKQKYLEVGRTMKEYEDRKYEQW 444
Query: 253 VQDASLFCDNMMKKNIL 269
++ +MKK++L
Sbjct: 445 MEVTEQVLPALMKKSLL 461
>U53531-1|AAB09728.1| 655|Homo sapiens cytoplasmic dynein 2 heavy
chain protein.
Length = 655
Score = 214 bits (523), Expect = 5e-54
Identities = 175/682 (25%), Positives = 313/682 (45%), Gaps = 36/682 (5%)
Query: 911 DELE-SRKKMLQAAEQL-FDNPLADFSNFNRTKADYSAMDQIYKIYKAQKNAREVWAKTL 968
D+LE +RKK++ + P +FS + D + QI+ Y+ + + A
Sbjct: 1 DDLEVTRKKLVDDCHHFRLEEP--NFSLASSNSKDIESCAQIWAFYEEFQQGFQEMANED 58
Query: 969 WVNLNPQALVDGIEQFFKEYR-KLPKIVRLSSTGLMLDLKMKQFKGVVPLMVSLKNEAMR 1027
W+ + + E+F + +L K+ S + L ++ ++K V+P++ ++ E +
Sbjct: 59 WITFRTKTYL--FEEFLMNWHVRLRKVEEHSVMTVKLQSEVDKYKIVIPILKYVRGEHLS 116
Query: 1028 ERHWKELMAKTGQDFDMSPDRFTLENMFAME---LHKYQDVAEEIVNHAIKELAIERGVK 1084
HW +L G S ++ ++ + + K D+ +++ + A E+ I ++
Sbjct: 117 PDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVAKAADL-KDLNSRAQGEVTIREALR 175
Query: 1085 DVQETWANISFSVSRHFNRGEDRGYTLNPCDDIVVKLDDDSMSLQSMAASQFIGPFLTVV 1144
++ F++ + + + DIV ++ D+ LQS+ S + F V
Sbjct: 176 ELDLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKV 235
Query: 1145 QTWEHRLSLISEIIEEWMATQRKWLYLEGIFVGGDIRTQLPEEAKKFDDIDRAFRKIMLD 1204
WE +L+ + E ++ QRKW+YLE IF G LP+E +F+ +D FR IM D
Sbjct: 236 SIWERKLAELDEYLQNLNHIQRKWVYLEPIFGRG----ALPKEQTRFNRVDEDFRSIMTD 291
Query: 1205 TAKRLNVVDCCTIGGRLEEFVNLGLGLQSSKIIRSASSDVTRKQINLSQAIAWADRASLS 1264
K V T G + + LQ + RS + + K+ + D L
Sbjct: 292 IKKDNRVTTLTTHAGIRNSLLTILDQLQRCQ--RSLNEFLEEKRSAFPRFYFIGDDDLLE 349
Query: 1265 LVPRSHLHAKAQAKRDTFSCVQPMFDNIRALDLYVDHTNRPVAAKMISAEGEIMDFRNVV 1324
++ +S + Q S ++ +F I ++ D ++ + A M S EGE++ F+N V
Sbjct: 350 ILGQSTNPSVIQ------SHLKKLFAGINSVCF--DEKSKHITA-MKSLEGEVVPFKNKV 400
Query: 1325 YTEGRVEDWMNLVLVEMRHTNKFITKKAIFYYGKNWKVPRTDWILEYQGMVCLAANGVWW 1384
VE W+N + +EM+ T + + K+ + G++ + D L ++CLA + +
Sbjct: 401 PLSNNVETWLNDLALEMKKTLEQLLKECVTT-GRSSQ-GAVDPSLFPSQILCLAEQ-IKF 457
Query: 1385 TAETEETFLRIKKGNKRAMKEHLQQQNEQLDGLVVKVRQDLSSND---RLKFRTITTIDV 1441
T + E IK + ++ L + EQ + ++ LK + + +
Sbjct: 458 TEDVENA---IKDHSLHQIETQLVNKLEQYTNIDTSSEDPGNTESGILELKLKALILDII 514
Query: 1442 HARDIIEGFVRDNITEAAEFEWESQLRFYWLKKDDNLWIRQCTGVFEYGYEYMGLNGRLV 1501
H D+++ + + ++ W+ QLRFY +K D ++ F+Y YEY G +LV
Sbjct: 515 HNIDVVKQLNQIQVHTTEDWAWKKQLRFY-MKSDHTCCVQMVDSEFQYTYEYQGNASKLV 573
Query: 1502 ITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDFRA 1561
TPLTD+ YLT+TQA+ M L L LG +V NC EG+D ++
Sbjct: 574 YTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKS 633
Query: 1562 VGQILAGLCQCGAWGCFDEFNR 1583
+G+I GL +CGAWGCFDEFNR
Sbjct: 634 MGRIFVGLVKCGAWGCFDEFNR 655
>AL117428-1|CAB55917.1| 591|Homo sapiens hypothetical protein
protein.
Length = 591
Score = 206 bits (503), Expect = 1e-51
Identities = 118/392 (30%), Positives = 197/392 (50%), Gaps = 11/392 (2%)
Query: 3768 QVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDEYIDF 3827
++ YGG +E++ D P H Y + IPP + Y+ +
Sbjct: 204 EINYGGRVTDDWDRRCIMNILEDFYNP---DVLSPEHSYSASGIYHQIPPTYDLHGYLSY 260
Query: 3828 IDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEAGGAMSREDFIDNIAV 3887
I +LPL + PE+FGLH NA I + + G +I+LQP++S AG + RE+ ++++
Sbjct: 261 IKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSSSAG-SQGREEIVEDVTQ 319
Query: 3888 DVLSKLPTLYEIWRVRKQFEMNITPTL-VVLLQELERFNRLISRMGSTLSLLRKALAGEI 3946
++L K+P + V ++ + ++ VL+QE+ R+NRL+ + TL L KAL G +
Sbjct: 320 NILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVITQTLQDLLKALKGLV 379
Query: 3947 GMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTKQYTDWATVEEPVVIW 4006
M + L+ ++ SL+N +P++W A A + K L W+ + R W P V W
Sbjct: 380 VMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQDGIPAVFW 439
Query: 4007 LSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVTSWVSADEIEERPVTGCYVRGLYLE 4066
+SG P+++L +Q R + +D + F + + E+ +RP GCY+ GL+LE
Sbjct: 440 ISGFFFPQAFLTGTLQNFARKFVISID-TISFDFKVMFEAPSELTQRPQVGCYIHGLFLE 498
Query: 4067 GARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRTPVYTTSQRRNAM---- 4122
GARWD + L S PK L TE+ +++++P K + Q+ P+Y T R +
Sbjct: 499 GARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTG 558
Query: 4123 -GVGLVFESDLWTTEHCSHWILQGVCLIMNTD 4153
V ++ T + HWI +GV LI D
Sbjct: 559 HSTNYVIAVEIPTHQPQRHWIKRGVALICALD 590
Score = 116 bits (280), Expect = 1e-24
Identities = 62/152 (40%), Positives = 88/152 (57%), Gaps = 7/152 (4%)
Query: 3619 FILSPGSDPTADLMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCH 3678
F+LSPG+DP ADL K A+ F K +SLGQGQ A +++ +I G+W+ QNCH
Sbjct: 1 FVLSPGTDPAADLYKFAEEMKFSK-KLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNCH 59
Query: 3679 LLVSFLRELEKQLELMT--KPHPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLNL 3733
L S++ LE+ +E + K H ++RLWLT+ P+ FP+ ILQ K EPP G++ NL
Sbjct: 60 LAPSWMPALERLIEHINPDKVHRDFRLWLTSLPSNKFPVSILQNGSKMTIEPPRGVRANL 119
Query: 3734 RNTYFKMRARALEECPH-PQFKKLVYVLAFFH 3764
+Y + L C +FK L+ L FH
Sbjct: 120 LKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFH 151
>AK126059-1|BAC86419.1| 933|Homo sapiens protein ( Homo sapiens cDNA
FLJ44071 fis, clone TESTI4037727, moderately similar to
Dynein beta chain, ciliary. ).
Length = 933
Score = 201 bits (491), Expect = 4e-50
Identities = 118/359 (32%), Positives = 191/359 (53%), Gaps = 18/359 (5%)
Query: 3421 VFSFSLRKAMPNVILVKRLKNIIDMLTKNVYDYGCTGIFERHKLLFSFQMDIKLEQSEDN 3480
VF ++++ P + +R+ N+ D +T +VY Y G+FER KL+F Q+ ++ +
Sbjct: 156 VFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKE 215
Query: 3481 VSQAQLDFFIKGNVSLEKSARSSPAPWMPAQGWQDIMKLSSDFPDPFATLPDDITKFLEE 3540
++ +LDF ++ K+ SP ++ QGW I LS D F L DI +
Sbjct: 216 LNPVELDFLLRFPF---KAGVVSPVDFLQHQGWGGIKALSE--MDEFKNLDSDIEGSAKR 270
Query: 3541 WQEWFDSDTPESAEIPNNYREKLKPFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPP 3600
W++ +S+ PE P ++ K + L ++RC R DR+ A+ +++ MG +++
Sbjct: 271 WKKLVESEAPEKEIFPKEWKNKTA-LQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGR 329
Query: 3601 VISLDMIVEQTTPFTPVVFILSPGSDPTADLMKLADRCGF--GGGKFKYLSLGQGQEGAA 3658
+ E+++P T + FILSPG DP D+ L + GF GK +SLGQGQE A
Sbjct: 330 SVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVA 389
Query: 3659 LSLLEGAISHGQWLILQNCHLLVSFLRELEKQLE-LMTKPHPEYRLWLTTDPTPT----- 3712
+ L+ A G W+ILQN HL+ +L L+K+LE T H +YR++++ +P P+
Sbjct: 390 ENALDVAAEKGHWVILQNIHLVARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHI 449
Query: 3713 FPIGILQRSLK---EPPNGLKLNLRNTYFKMRARALEEC-PHPQFKKLVYVLAFFHAVV 3767
P GIL+ ++K EPP G+ NL LE C +FK +++ L +FHAVV
Sbjct: 450 IPQGILENAIKITNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVV 508
Score = 193 bits (471), Expect = 1e-47
Identities = 116/386 (30%), Positives = 193/386 (50%), Gaps = 15/386 (3%)
Query: 3768 QVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDEYIDF 3827
++MYGG TY+ EY+ + + A + IPP + Y ++
Sbjct: 558 EIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLL------APGFQIPPNLDYKGYHEY 611
Query: 3828 IDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSE--AGGAMSREDFIDNI 3885
ID +P ++GLHPNAEIG+ + +++ ++E+QP+ ++ AG +SRE+ + +
Sbjct: 612 IDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVKAV 671
Query: 3886 AVDVLSKLPTLYEIWRVRKQFEMNITPTLVVLLQELERFNRLISRMGSTLSLLRKALAGE 3945
D+L K+P + + + + TP +VV QE ER N L + M +L L L GE
Sbjct: 672 LDDILEKIPETFNMAEIMAKAAEK-TPYVVVAFQECERMNILTNEMRRSLKELNLGLKGE 730
Query: 3946 IGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTKQYTDWAT-VEEPVV 4004
+ + ++++S +LF +P W A A + GL W + R ++ W T P
Sbjct: 731 LTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTT 790
Query: 4005 IWLSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVTSWVSADEIEERPVTGCYVRGLY 4064
+WL+G P+S+L A +Q R WPLD+ +VT + +++ P G YV GL+
Sbjct: 791 VWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTK-KNREDMTAPPREGSYVYGLF 849
Query: 4065 LEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRTPVYTTSQRRNAMGV 4124
+EGARWD G + + K L +P+++I I +++ +N PVY T R G
Sbjct: 850 MEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIR----GP 905
Query: 4125 GLVFESDLWTTEHCSHWILQGVCLIM 4150
V+ +L T E + WIL V L++
Sbjct: 906 TYVWTFNLKTKEKAAKWILAAVALLL 931
>AL357912-1|CAI95150.1| 234|Homo sapiens dynein, axonemal, heavy
chain 14 protein.
Length = 234
Score = 200 bits (487), Expect = 1e-49
Identities = 108/237 (45%), Positives = 153/237 (64%), Gaps = 17/237 (7%)
Query: 1539 DLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQC 1598
DLAK+LG CVV NC E +D++ V + GL Q GAW CFDEFN ID+ VLSVI++Q+
Sbjct: 12 DLAKSLGKHCVVFNCFEDLDYKIVRKFFFGLVQSGAWSCFDEFNLIDLEVLSVIASQILT 71
Query: 1599 IRSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTEL 1658
I++A R+ VL+ G+EI ++ +FITMNP Y G EL
Sbjct: 72 IKAAKDNYSARYLF---VLE--------------GKEIRINMSCAVFITMNPRYGGGVEL 114
Query: 1659 PESVKALFRPVVCILPDLEMICQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDW 1718
P+++K+LFRPV ++P +MI +I LFS GF +A L+ K+T LY++AR+QLS+Q HY++
Sbjct: 115 PDNLKSLFRPVAMMVPHYQMIAEIILFSFGFKSANSLSGKLTNLYELARKQLSQQDHYNF 174
Query: 1719 GLRALTAVLRMAGKLRRDSPGLSEIMVLMRALRDMNHPKFVFEDVPLFLGLIKDLFP 1775
GLR+L VL MAG +RD E ++++ A+R+ + PK EDVPLF +I D+FP
Sbjct: 175 GLRSLKIVLIMAGTKKRDLSEADETLIVIEAIREASLPKCPPEDVPLFENIIGDIFP 231
>AK026756-1|BAB15543.1| 394|Homo sapiens protein ( Homo sapiens cDNA:
FLJ23103 fis, clone LNG07621. ).
Length = 394
Score = 200 bits (487), Expect = 1e-49
Identities = 127/399 (31%), Positives = 195/399 (48%), Gaps = 15/399 (3%)
Query: 3754 KKLVYVLAFFHAVVQVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDY 3813
KK V + + ++ YGG T+ + + E +F F FY+ Y
Sbjct: 4 KKGVSWTTIRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSENMFGP--DFSFYQGYN--- 58
Query: 3814 VIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEAG 3873
IP D Y+ +I +LP ++PEVFGLHPNA+I Y S+ +++ ++ +QP+ + G
Sbjct: 59 -IPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDVLDTILGIQPKDTSGG 117
Query: 3874 GAMSREDFIDNIAVDVLSKLPTLYEIWRVRKQFEM--NITPTLVVLLQELERFNRLISRM 3931
G +RE + +A D+L KLP Y + V+++ + P + L QE++R R++S +
Sbjct: 118 GDETREAVVARLADDMLEKLPPDYVPFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLV 177
Query: 3932 GSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTK 3991
STL+ L+ A+ G I M L + +F+ ++P W+ A LG W I R
Sbjct: 178 RSTLTELKLAIDGTIIMSENLQDALDCMFDARIPAWWKK-ASWVFSTLGFWFTELIERNS 236
Query: 3992 QYTDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYT-WPLDRSTQFTKVTSWVSADEI 4050
Q+T W P W++G P+ +L A Q R W LD +VT W+ D+I
Sbjct: 237 QFTSWVFNGRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVLCNEVTKWMK-DDI 295
Query: 4051 EERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRT 4110
P G YV GLYLEGA WD L S PKVL +P++ I E + L+
Sbjct: 296 STPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIRIY-AENNTLRDPRFYSC 354
Query: 4111 PVYTTSQRRNAMGVGLVFESDLWTTEHCSHWILQGVCLI 4149
P+Y R + + V DL T + HW+L+GV L+
Sbjct: 355 PIYKKPVRTDLNYIAAV---DLRTAQTPEHWVLRGVALL 390
>AC002394-2|AAC05809.1| 573|Homo sapiens Gene product with similarity
to dynein beta subunit protein.
Length = 573
Score = 200 bits (487), Expect = 1e-49
Identities = 118/347 (34%), Positives = 182/347 (52%), Gaps = 9/347 (2%)
Query: 3813 YVIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEA 3872
Y IPP G YID++ LP+ PEVFGLH NA+I +Q +++ ++ P+ S
Sbjct: 229 YYIPPHGSYQSYIDYLRNLPITAHPEVFGLHENADITKDNQETNQLFEGVLLTLPRQS-G 287
Query: 3873 GGAMSREDFIDNIAVDVLSKLPTLYEIWRVRKQFEMNITPTL-VVLLQELERFNRLISRM 3931
G S ++ ++ +A D+LSKLP +++ V K + + ++ VL QEL RFNRL +
Sbjct: 288 GSGKSPQEVVEELAQDILSKLPRDFDLEEVMKLYPVVYEESMNTVLRQELIRFNRLTKVV 347
Query: 3932 GSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTK 3991
+L L +A+ G++ M + L+ V S+ G++P +W A + + K LGG++ +AR
Sbjct: 348 RRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARLT 407
Query: 3992 QYTDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVTSWVSADEIE 4051
+ +W PVV W+SG + +S+L Q R YT P+D +VT + +E
Sbjct: 408 FFQEWIDKGPPVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFEVTPQETV--ME 465
Query: 4052 ERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRTP 4111
P G Y++GL+LEGARWD + S PK+L LPI+++ P E Q+ P
Sbjct: 466 NNPEDGAYIKGLFLEGARWDRKTMQIGESLPKILYDPLPIIWLKPGESAMFLHQDIYVCP 525
Query: 4112 VYTTSQRRNAM-----GVGLVFESDLWTTEHCSHWILQGVCLIMNTD 4153
VY TS RR + V +L T HWI +GV + D
Sbjct: 526 VYKTSARRGTLSTTGHSTNYVLSIELPTDMPQKHWINRGVASLCQLD 572
Score = 99 bits (238), Expect = 2e-19
Identities = 55/138 (39%), Positives = 79/138 (57%), Gaps = 10/138 (7%)
Query: 3641 GGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFLRELEKQLELMTKP--- 3697
GG + + +SLGQGQ A ++ AI G W++LQNCHL S++ LEK E + P
Sbjct: 2 GGTRTQTISLGQGQGPIAAKMINNAIKDGTWVVLQNCHLAASWMPTLEKICEEVIVPEST 61
Query: 3698 HPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLNLRNTYFK---MRARALEECPHP 3751
+ +RLWLT+ P+ FP+ ILQ +K EPP GL+ NL +Y + C
Sbjct: 62 NARFRLWLTSYPSEKFPVSILQNGIKMTNEPPKGLRANLLRSYLNDPISDPVFFQSCAKA 121
Query: 3752 -QFKKLVYVLAFFHAVVQ 3768
++K+++ L FFHAVVQ
Sbjct: 122 VMWQKMLFGLCFFHAVVQ 139
>BC029567-1|AAH29567.1| 507|Homo sapiens DNAH7 protein protein.
Length = 507
Score = 190 bits (463), Expect = 9e-47
Identities = 107/352 (30%), Positives = 186/352 (52%), Gaps = 14/352 (3%)
Query: 3808 DYAFD----YVIPPEGERDEYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLI 3863
DY FD Y +PP G+ YI++ TLPL PE+FG++ NA+I + ++ +++
Sbjct: 155 DYKFDSSGIYFVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNIL 214
Query: 3864 ELQPQTSEAGGAMSREDFIDNIAVDVLSKLPTLYEIWRVRKQFEMNITPTL-VVLLQELE 3922
Q +++ AG A S ++ ++ +A D+L KLP ++I +++ T ++ VL+QE+
Sbjct: 215 LTQSRSAGAG-AKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQSMNTVLVQEMG 273
Query: 3923 RFNRLISRMGSTLSLLRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGW 3982
RFN+L+ + + ++KA+ G M L+ V S+ N ++P++W + + K LG +
Sbjct: 274 RFNKLLKTIRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSY 333
Query: 3983 MDHFIARTKQYTDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVT 4042
++ F+AR K W V P V WLSG +++L Q R YT P+D +V
Sbjct: 334 VNDFLARLKFLQQWYEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEV- 392
Query: 4043 SWVSADEIEERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKL 4102
+ E + P G ++ GL+L+GA W+ L SHPK+L +P+M++ P + +
Sbjct: 393 --MEDKEYKHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADI 450
Query: 4103 KLQNTLRTPVYTTSQRRNAM-----GVGLVFESDLWTTEHCSHWILQGVCLI 4149
+ + P+Y TS+RR + V L + + HWI +GV L+
Sbjct: 451 PKRPSYVAPLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALL 502
Score = 60.9 bits (141), Expect = 1e-07
Identities = 32/73 (43%), Positives = 44/73 (60%), Gaps = 7/73 (9%)
Query: 3703 LWLTTDPTPTFPIGILQRSLK---EPPNGLKLNLRNTYFKMRARALE---ECPHP-QFKK 3755
+WLT+ P+P FP+ +LQ +K E P GL+ N+ +Y LE C P +FKK
Sbjct: 1 MWLTSYPSPNFPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDLEFFGSCKKPEEFKK 60
Query: 3756 LVYVLAFFHAVVQ 3768
L+Y L FFHA+VQ
Sbjct: 61 LLYGLCFFHALVQ 73
>Z83805-1|CAB06059.1| 177|Homo sapiens axonemal dynein heavy chain
protein.
Length = 177
Score = 175 bits (426), Expect = 3e-42
Identities = 86/183 (46%), Positives = 120/183 (65%), Gaps = 19/183 (10%)
Query: 1540 LAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCI 1599
LAKAL CVV NC +G+D++A+G+ GL Q GAW CFDEFNRI++ VLSV++ Q+ I
Sbjct: 14 LAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILSI 73
Query: 1600 RSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTELP 1659
+ A++ KLK F G E++++ +FITMNPGYAGR ELP
Sbjct: 74 QQAIIRKLKTFIFE-------------------GTELSLNPTCAVFITMNPGYAGRAELP 114
Query: 1660 ESVKALFRPVVCILPDLEMICQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDWG 1719
+++KALFR V ++PD +I +ISL+S GFL ++ LA+K+ Y++ EQLS Q HYD+G
Sbjct: 115 DNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDFG 174
Query: 1720 LRA 1722
L A
Sbjct: 175 LHA 177
>AK095579-1|BAC04578.1| 806|Homo sapiens protein ( Homo sapiens cDNA
FLJ38260 fis, clone FCBBF3001377, highly similar to
Rattus norvegicus dnchc2 mRNA for cytoplasmic dynein
heavy ).
Length = 806
Score = 175 bits (426), Expect = 3e-42
Identities = 105/381 (27%), Positives = 203/381 (53%), Gaps = 16/381 (4%)
Query: 3397 LFFVLSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDMLTKNVYDYGCT 3456
++F++SD++ +N+MY++SL+++L +F +L+ + +R++++I L VY+Y C
Sbjct: 1 MYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYICR 60
Query: 3457 GIFERHKLLFSFQM------DIKLEQSEDNVSQAQLDFFIKGNVSLEKSARSSPAPWMPA 3510
+F+ +L+F+ ++ E D + + ++ S +K P+ W+
Sbjct: 61 CLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPS-WIDQ 119
Query: 3511 QGWQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLKPFELLM 3570
+ + L P + TL + W+ ++++ E E P+ +K+ F+ ++
Sbjct: 120 ERSWAVATLKIALPSLYQTLCFEDAAL---WRTYYNNSMCEQ-EFPSILAKKVSLFQQIL 175
Query: 3571 LLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPGSDPTAD 3630
+++ R DR+ A+ + T+G + ++P ++L + ++T P++ I+SPG+DP+ +
Sbjct: 176 VVQALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEIEPILIIISPGADPSQE 235
Query: 3631 LMKLADRCGFGGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFLRELEKQ 3690
L +LA+ G + +++GQGQ A+ +L+ +G WL L+N HL+VS+L LEK+
Sbjct: 236 LQELAN-AERSGECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKE 294
Query: 3691 LELMTKPHPEYRLWLTTDPTPTFPIGILQRSLK---EPPNGLKLNLRNTYFKMRARALEE 3747
L + +P +RLWLT + P F +LQ SLK E P GLK NL TY + +
Sbjct: 295 LNTL-QPKDTFRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTYESWTPEQISK 353
Query: 3748 CPHPQFKKLVYVLAFFHAVVQ 3768
+ ++ LA+FHA Q
Sbjct: 354 KDNTHRAHALFSLAWFHAACQ 374
>Z83801-1|CAB06055.1| 169|Homo sapiens axonemal dynein heavy chain
protein.
Length = 169
Score = 163 bits (397), Expect = 9e-39
Identities = 82/181 (45%), Positives = 114/181 (62%), Gaps = 19/181 (10%)
Query: 1539 DLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQC 1598
DLAKA+ CVV +C +G+D+ A+G+ GL CGAW CFDEFNRID+ VLSV++ Q+
Sbjct: 8 DLAKAVAKQCVVFDCPDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILT 67
Query: 1599 IRSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTEL 1658
I+ + D+L G E+ +D +FITMNPGYAGR+EL
Sbjct: 68 IQRGI-------NAGADILMFE------------GTELKLDPTCAVFITMNPGYAGRSEL 108
Query: 1659 PESVKALFRPVVCILPDLEMICQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYDW 1718
P+++KALFR V ++PD MI +I L+S GF+TA+ L+ K+ Y++ EQLS Q HYD+
Sbjct: 109 PDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHHYDY 168
Query: 1719 G 1719
G
Sbjct: 169 G 169
>Z83802-1|CAB06056.1| 179|Homo sapiens axonemal dynein heavy chain
protein.
Length = 179
Score = 162 bits (393), Expect = 3e-38
Identities = 84/185 (45%), Positives = 118/185 (63%), Gaps = 19/185 (10%)
Query: 1539 DLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQC 1598
DLAKAL + CVV NC +G+D+ A+G+ GL GAW CFDEFNRI++ VLSV++ Q+ C
Sbjct: 13 DLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILC 72
Query: 1599 IRSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSK-VGIFITMNPGYAGRTE 1657
I+ A+ KL F G E+ ++ V + ITMNPGYAG +E
Sbjct: 73 IQRAIQQKLVVFWF------------------LEGTELKLNPGIVFVAITMNPGYAGHSE 114
Query: 1658 LPESVKALFRPVVCILPDLEMICQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHYD 1717
LP+++K LFR V ++P+ +I +ISL+S GFL A+ L+ K+ + Y++ EQLS Q HYD
Sbjct: 115 LPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNARPLSVKIVMTYRLCSEQLSSQFHYD 174
Query: 1718 WGLRA 1722
+GLRA
Sbjct: 175 YGLRA 179
>Z83800-1|CAB06054.1| 179|Homo sapiens cytoplasmic dynein heavy chain
protein.
Length = 179
Score = 155 bits (375), Expect = 4e-36
Identities = 81/183 (44%), Positives = 117/183 (63%), Gaps = 22/183 (12%)
Query: 1540 LAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCI 1599
L LG +V NC EG+D +++G+I GL +CGAWGCFDEFNR++ SVLS +S Q+Q I
Sbjct: 14 LGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTI 73
Query: 1600 RSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNP---GYAGRT 1656
+ AL K ++L G+E+ ++S GIFITMNP GY GR
Sbjct: 74 QDAL----KNHRTVCELL---------------GKEVEVNSHSGIFITMNPAGKGYGGRQ 114
Query: 1657 ELPESVKALFRPVVCILPDLEMICQISLFSDGFLTAKVLAKKMTVLYKVAREQLSKQSHY 1716
+LP+++K LFRPV PD E+I ++ L+S+GF AKVL++K+ ++ ++RE L+ Q HY
Sbjct: 115 KLPDNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHY 174
Query: 1717 DWG 1719
D+G
Sbjct: 175 DYG 177
>U53532-1|AAB09729.1| 197|Homo sapiens cytoplasmic dynein 3 heavy
chain protein.
Length = 197
Score = 155 bits (375), Expect = 4e-36
Identities = 77/200 (38%), Positives = 111/200 (55%), Gaps = 5/200 (2%)
Query: 1384 WTAETEETFLRIKKGNKRAMKEHLQQQNEQLDGLVVKVRQDLSSNDRLKFRTITTIDVHA 1443
WT+ET+E G +K++ ++ QL+ +V VR LS R + TIDV A
Sbjct: 1 WTSETQEVI----GGGTEGLKKYYKELQNQLNEIVELVRGKLSKQTRTTLGALVTIDVRA 56
Query: 1444 RDIIEGFVRDNITEAAEFEWESQLRFYWLKKDDNLWIRQCTGVFEYGYEYMGLNGRLVIT 1503
RD++ ++ ++ +F W +QLR+YW ++ + I Q + +Y YEY+G + RLVIT
Sbjct: 57 RDVVMDMIKMGVSHDTDFLWLAQLRYYWENENARVRIIQLP-MLKYAYEYLGNSPRLVIT 115
Query: 1504 PLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDFRAVG 1563
PLTDR Y T+ A + L DLAKAL + CVV NC +G+D+ A+G
Sbjct: 116 PLTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMG 175
Query: 1564 QILAGLCQCGAWGCFDEFNR 1583
+ GL GAW CFDEFNR
Sbjct: 176 KFFKGLASSGAWACFDEFNR 195
>BC015442-1|AAH15442.1| 551|Homo sapiens LOC200383 protein protein.
Length = 551
Score = 153 bits (370), Expect = 2e-35
Identities = 101/330 (30%), Positives = 167/330 (50%), Gaps = 24/330 (7%)
Query: 2055 TVVECVFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVEDNPEKKATTKHFPMGFPTL 2114
T++ F+ SLG + +N FD +I+ +DNP+ + L
Sbjct: 8 TILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQ-----FDDNPDARLPNSG------DL 56
Query: 2115 YDYCLELTTKLWEAWDWLVPEYEHDRDMKFPAILVPTVDTLRLTWLIKIMESIIQQMNFS 2174
+ ++ TK + W+ ++P ++++RD+ F +LVPT DT+R +L++ + ++ + F+
Sbjct: 57 WSIHMDFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFT 116
Query: 2175 SRT---SSMDVQRNLESVVEKR----TKDTFGPPVGKRMLVFIDDMNMPIVSHNNQCVPS 2227
T S+ + L + E F I + + N P
Sbjct: 117 GITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERKRKNILGAPG 176
Query: 2228 LCSTRVQTL---LSHPLVDTYGTQQPIALLKLLFERKGFYDRGKDLNWKNLKDIGFLAAM 2284
+ R+ L+ P +D YG+Q PI LL+ + GFYDR K L WK ++D+ ++A
Sbjct: 177 --NKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNK-LFWKEIQDVTIISAC 233
Query: 2285 GKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSILKGHFEIFPEEIQGIVEKIVQM 2344
GGGRN V PRFI FS+ L PSE++L+ I+ +IL G FP ++ IV+
Sbjct: 234 APPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSDFPPAVKQTASSIVEA 293
Query: 2345 TLDLYKIIIVELPPTPAKFHYIFNLRDLSR 2374
++++Y + V+L PTPAK HY+FNLRDLS+
Sbjct: 294 SVEIYNKMSVDLLPTPAKSHYVFNLRDLSK 323
Score = 139 bits (336), Expect = 2e-31
Identities = 68/186 (36%), Positives = 110/186 (59%), Gaps = 1/186 (0%)
Query: 2494 YVLRDPMLFGDYRNALDEEEIRYYEDLLDYEAIYFLFQEILDEYNERNAK-MSIVLFEDC 2552
Y L P++FGD+ ++ R Y+D+ D E + Q+ LD+YN N K + +V F+D
Sbjct: 338 YFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNPKEVKLVFFQDA 397
Query: 2553 LEHLTRTHRILRMDRGNAMXXXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDD 2612
+EH++R R++R +RGNA+ +LAA G + +I ++R YN ++F +D
Sbjct: 398 IEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHED 457
Query: 2613 MKRMYLQLGVDNKKTVFLFTAAQILEEGFLEFINNILMIGMIPALFGDDEKDSIINSVRN 2672
++++Y GV++K VFLFT QI+ E FLE INNIL G +P LF DE + ++ + R
Sbjct: 458 LRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQVLAATRP 517
Query: 2673 DSSDAG 2678
+ + G
Sbjct: 518 RAKEVG 523
>AC098975-1|AAX93115.1| 326|Homo sapiens unknown protein.
Length = 326
Score = 153 bits (370), Expect = 2e-35
Identities = 101/330 (30%), Positives = 167/330 (50%), Gaps = 24/330 (7%)
Query: 2055 TVVECVFMVSMYNSLGAAIVDNGRYDFDNYIKKACPMMLVEDNPEKKATTKHFPMGFPTL 2114
T++ F+ SLG + +N FD +I+ +DNP+ + L
Sbjct: 8 TILCQTFVFCYLWSLGGNLTENYYDSFDTFIRTQ-----FDDNPDARLPNSG------DL 56
Query: 2115 YDYCLELTTKLWEAWDWLVPEYEHDRDMKFPAILVPTVDTLRLTWLIKIMESIIQQMNFS 2174
+ ++ TK + W+ ++P ++++RD+ F +LVPT DT+R +L++ + ++ + F+
Sbjct: 57 WSIHMDFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLMEKLLAVKHSVLFT 116
Query: 2175 SRT---SSMDVQRNLESVVEKR----TKDTFGPPVGKRMLVFIDDMNMPIVSHNNQCVPS 2227
T S+ + L + E F I + + N P
Sbjct: 117 GITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERKRKNILGAPG 176
Query: 2228 LCSTRVQTL---LSHPLVDTYGTQQPIALLKLLFERKGFYDRGKDLNWKNLKDIGFLAAM 2284
+ R+ L+ P +D YG+Q PI LL+ + GFYDR K L WK ++D+ ++A
Sbjct: 177 --NKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNK-LFWKEIQDVTIISAC 233
Query: 2285 GKAGGGRNDVDPRFISMFSVYNLQFPSENTLRHIYVSILKGHFEIFPEEIQGIVEKIVQM 2344
GGGRN V PRFI FS+ L PSE++L+ I+ +IL G FP ++ IV+
Sbjct: 234 APPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSDFPPAVKQTASSIVEA 293
Query: 2345 TLDLYKIIIVELPPTPAKFHYIFNLRDLSR 2374
++++Y + V+L PTPAK HY+FNLRDLS+
Sbjct: 294 SVEIYNKMSVDLLPTPAKSHYVFNLRDLSK 323
>AF015265-1|AAC27542.1| 377|Homo sapiens axonemal dynein protein.
Length = 377
Score = 151 bits (366), Expect = 5e-35
Identities = 85/233 (36%), Positives = 128/233 (54%), Gaps = 13/233 (5%)
Query: 3547 SDTPESAEIPNNYREKLKPFELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDM 3606
S+ PE ++P ++ K + L +LR R DR+ AL D++ +G +Y+ +
Sbjct: 1 SECPEKEKLPQEWKNKTA-LQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFAT 59
Query: 3607 IVEQTTPFTPVVFILSPGSDPTADLMKLADRCG--FGGGKFKYLSLGQGQEGAALSLLEG 3664
E++ P TP+ FILSPG DP D+ + G F F +SLGQGQE A + L+
Sbjct: 60 SFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDL 119
Query: 3665 AISHGQWLILQNCHLLVSFLRELEKQLELMTK-PHPEYRLWLTTDPTPT-----FPIGIL 3718
A G W+ILQN HL+ +L LEK+LE ++ HPE+R++++ +P P+ P GIL
Sbjct: 120 AAKKGHWVILQNIHLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGIL 179
Query: 3719 QRSLK---EPPNGLKLNLRNTYFKMRARALEECP-HPQFKKLVYVLAFFHAVV 3767
+ S+K EPP G+ NL LE C +FK +++ L +FHAVV
Sbjct: 180 ENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVV 232
Score = 46.4 bits (105), Expect = 0.002
Identities = 27/101 (26%), Positives = 49/101 (48%), Gaps = 6/101 (5%)
Query: 3768 QVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDEYIDF 3827
++MYGG TY+ E + + + A + +P + + Y +
Sbjct: 282 EIMYGGHITDDWDRRLCRTYLGEVIRPEMLEG------ELSLAPGFPLPGNMDYNGYHQY 335
Query: 3828 IDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQ 3868
ID +P ++GLHPNAEIG+ +Q +++ ++ELQP+
Sbjct: 336 IDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPR 376
>AC010087-1|AAX93108.1| 224|Homo sapiens unknown protein.
Length = 224
Score = 139 bits (336), Expect = 2e-31
Identities = 68/186 (36%), Positives = 110/186 (59%), Gaps = 1/186 (0%)
Query: 2494 YVLRDPMLFGDYRNALDEEEIRYYEDLLDYEAIYFLFQEILDEYNERNAK-MSIVLFEDC 2552
Y L P++FGD+ ++ R Y+D+ D E + Q+ LD+YN N K + +V F+D
Sbjct: 11 YFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNPKEVKLVFFQDA 70
Query: 2553 LEHLTRTHRILRMDRGNAMXXXXXXXXXXXXCKLAAFAAGCEMFEITVTRNYNENTFKDD 2612
+EH++R R++R +RGNA+ +LAA G + +I ++R YN ++F +D
Sbjct: 71 IEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHED 130
Query: 2613 MKRMYLQLGVDNKKTVFLFTAAQILEEGFLEFINNILMIGMIPALFGDDEKDSIINSVRN 2672
++++Y GV++K VFLFT QI+ E FLE INNIL G +P LF DE + ++ + R
Sbjct: 131 LRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQVLAATRP 190
Query: 2673 DSSDAG 2678
+ + G
Sbjct: 191 RAKEVG 196
>AJ132089-1|CAA10562.1| 101|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 101
Score = 138 bits (334), Expect = 4e-31
Identities = 71/112 (63%), Positives = 83/112 (74%), Gaps = 19/112 (16%)
Query: 1539 DLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQC 1598
DLAKALGLLCVVTNCGEGMD+RAVG+I +GL QCGAWGCFDEFNRID SVLSVIS+Q+Q
Sbjct: 9 DLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQT 68
Query: 1599 IRSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNP 1650
IR+AL+ +L F GQEI++DS++GIFITMNP
Sbjct: 69 IRNALIHQLTTFQFE-------------------GQEISLDSRMGIFITMNP 101
>AK027182-1|BAB15685.1| 366|Homo sapiens protein ( Homo sapiens cDNA:
FLJ23529 fis, clone LNG06042. ).
Length = 366
Score = 135 bits (327), Expect = 3e-30
Identities = 83/324 (25%), Positives = 151/324 (46%), Gaps = 25/324 (7%)
Query: 3823 EYIDFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEAGGAMSREDFI 3882
E+ D+I+ LPL + PE+FG+H NA + + + + ++E+QP++S G S ++ +
Sbjct: 7 EFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILEVQPRSSTGGEGKSNDEIV 66
Query: 3883 DNIAVDVLSKLPTLYEIWRVR-----KQFEMNITPTLVVLLQELERFNRLISRMGSTLSL 3937
+ V +++P E+ K + + VL QE++RFN L+ + ++L
Sbjct: 67 QELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTTVLGQEVDRFNNLLKLIHTSLET 126
Query: 3938 LRKALAGEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTKQYTDWA 3997
L KA+AG + M ++ V S N Q+P +W A + K LG W+ I RT W
Sbjct: 127 LNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLGSWVRDLILRTSFVDLWL 186
Query: 3998 TVEEPVVIWLSGLHIPESYLIAHVQIACRLYTWPLDR-STQFTKVTSWVSADEIEE---- 4052
+P W+SG P+ +L +Q R Y P+D S +++ + ++ + E
Sbjct: 187 KRGQPKSYWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKYSVIPTYRDQAAVIEAAKT 246
Query: 4053 --------------RPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPIE 4098
P G V G++++ +RWD E ++ + P + LP+++ P +
Sbjct: 247 VQFGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDALPGQMNPVLPVVHFEPQQ 306
Query: 4099 FHKLKLQNTLRTPVYTTSQRRNAM 4122
+K P+Y T R +
Sbjct: 307 NYK-PSPTLYHCPLYKTGARAGTL 329
>AK054657-1|BAB70785.1| 333|Homo sapiens protein ( Homo sapiens cDNA
FLJ30095 fis, clone BNGH41000039, moderately similar to
DYNEIN BETA CHAIN, CILIARY. ).
Length = 333
Score = 134 bits (324), Expect = 6e-30
Identities = 80/204 (39%), Positives = 112/204 (54%), Gaps = 12/204 (5%)
Query: 3576 RVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPGSDPTADLMKLA 3635
R DR+ AL +++ +G +Y+ + L E+++P TP+ FILSPG D DL L
Sbjct: 2 RPDRMTYALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILG 61
Query: 3636 DRCGF--GGGKFKYLSLGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFLRELEKQLEL 3693
R GF GKF +SLGQGQE A LE A G W+ILQN HL+ +L LEK LE
Sbjct: 62 KRLGFTIDSGKFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLER 121
Query: 3694 MTK-PHPEYRLWLTTDPTPT-----FPIGILQRSLK---EPPNGLKLNLRNTYFKMRARA 3744
++ H +YR++++ + PT P G+L+ S+K EPP G+ NL +
Sbjct: 122 FSQGSHRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQDT 181
Query: 3745 LEECPHPQ-FKKLVYVLAFFHAVV 3767
LE C Q FK + + L +FHA V
Sbjct: 182 LEICSKEQEFKSIFFSLCYFHACV 205
Score = 36.7 bits (81), Expect = 1.8
Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 6/83 (7%)
Query: 3768 QVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDEYIDF 3827
++MYGG Y+EE++ L + A + PP + Y +
Sbjct: 255 EIMYGGHITDDWDRKLCRVYLEEFVNPSLIEDELML------APGFAAPPYLDYAGYHQY 308
Query: 3828 IDTLPLANTPEVFGLHPNAEIGY 3850
I+ + +P ++GLHPNAEI +
Sbjct: 309 IEEMLPPESPALYGLHPNAEIEF 331
>AJ132085-1|CAA10558.1| 143|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 143
Score = 131 bits (316), Expect = 6e-29
Identities = 60/122 (49%), Positives = 79/122 (64%)
Query: 1489 YGYEYMGLNGRLVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLC 1548
YG+EY+G + RLVITPLTDR Y T+ AL + L DLAKAL C
Sbjct: 1 YGFEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTKDLAKALAKQC 60
Query: 1549 VVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLK 1608
VV NC +G+D++A+G+ GL Q GAW CFDEFNRI++ VLSV++ Q+ I+ A++ KLK
Sbjct: 61 VVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILSIQQAIIRKLK 120
Query: 1609 RF 1610
F
Sbjct: 121 TF 122
>AJ132083-1|CAA10556.1| 143|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 143
Score = 126 bits (305), Expect = 1e-27
Identities = 59/122 (48%), Positives = 77/122 (63%)
Query: 1489 YGYEYMGLNGRLVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLC 1548
YG+EY+G +GRLVITPLTDR YLT+T AL ++ DL KAL +
Sbjct: 1 YGFEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQT 60
Query: 1549 VVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLK 1608
VV NC + +DF A+G+ GL GAW CFDEFNRIDI VLSV++ Q+ I+ A +++
Sbjct: 61 VVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQRVE 120
Query: 1609 RF 1610
RF
Sbjct: 121 RF 122
>U20552-1|AAB50020.1| 161|Homo sapiens dynein heavy chain, isotype 1B
protein.
Length = 161
Score = 126 bits (304), Expect = 2e-27
Identities = 73/179 (40%), Positives = 101/179 (56%), Gaps = 22/179 (12%)
Query: 1510 YLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDFRAVGQILAGL 1569
YLT+TQA+ M L L LG +V NC EG+D +++G+I GL
Sbjct: 2 YLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGL 61
Query: 1570 CQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLKRFTVNTDVLKPSQKFGRLKTK 1629
+CGAWGCFDEFNR++ SVLS +S Q+Q I+ AL K ++L
Sbjct: 62 VKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDAL----KNHRTVCELL------------ 105
Query: 1630 RRAGQEIAMDSKVGIFITMNP---GYAGRTELPESVKALFRPVVCILPDLEMICQISLF 1685
G+E+ ++S GIFITMNP GY GR +LP+++K LFRPV PD E+I ++ L+
Sbjct: 106 ---GKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEVILY 161
>AJ132084-1|CAA10557.1| 143|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 143
Score = 121 bits (292), Expect = 5e-26
Identities = 66/162 (40%), Positives = 87/162 (53%), Gaps = 19/162 (11%)
Query: 1489 YGYEYMGLNGRLVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLC 1548
YG+EY+G + RLVITPLTDR Y T+ AL + L DLAKA+ C
Sbjct: 1 YGFEYLGNSPRLVITPLTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQC 60
Query: 1549 VVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLK 1608
VV NC +G+D+ A+G+ GL CGAW CFDEFNRID+ VLSV++ Q+ I+ +
Sbjct: 61 VVFNCSDGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGI----- 115
Query: 1609 RFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNP 1650
D+L G E+ +D +FITMNP
Sbjct: 116 --NAGADIL------------MFEGTELKLDPTCAVFITMNP 143
>BC021297-1|AAH21297.1| 832|Homo sapiens DYNC1H1 protein protein.
Length = 832
Score = 116 bits (279), Expect = 2e-24
Identities = 97/390 (24%), Positives = 194/390 (49%), Gaps = 35/390 (8%)
Query: 3401 LSDMAGVNSMYQYSLSSYLDVFSFSLRKAMPNVILVKRLKNIIDMLTKNVYDYG----CT 3456
+ + ++ +YQYSL +LD++ L + PN+ V + ++TK+++
Sbjct: 1 MESLKQIHFLYQYSLQFFLDIYHNVLYEN-PNLKGVTDHTQRLSIITKDLFQVAFNRVAR 59
Query: 3457 GIFERHKLLFSFQMD-IKLEQSEDNVS-QAQLDFFIKGNVSLEKSARSSPA-PWMPAQGW 3513
G+ + + F+ + IKL+ + + A+ F++GN + SA S+P + +
Sbjct: 60 GMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGN-EIVLSAGSTPRIQGLTVEQA 118
Query: 3514 QDIMKLSS--DFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKL------KP 3565
+ +++LS F D A + D E++ W DS +PE +P + E+ +
Sbjct: 119 EAVVRLSCLPAFKDLIAKVQAD-----EQFGIWLDSSSPEQT-VPYLWSEETPATPIGQA 172
Query: 3566 FELLMLLRCFRVDRIYRALTDYITVTMGEEYITPPVISLDM---IVEQTTPFTPVVFILS 3622
L+L++ FR DR+ +++ +GE +++ LD+ + + P TPV+
Sbjct: 173 IHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSV 232
Query: 3623 PGSDPTADLMKLADRCGFGGGKFKYLSLGQGQE-GAALSLLEGAISHGQWLILQNCHLLV 3681
PG D + + LA + +++G + A + A+ G+W++L+N HL
Sbjct: 233 PGYDASGHVEDLAAE---QNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAP 289
Query: 3682 SFLRELEKQLELMTKPHPEYRLWLTTDPTPTFPIGILQRS---LKEPPNGLKLNLRNTYF 3738
+L +LEK+L + +PH +RL+LT + P P+ +L+ + EPP G+K N+ T+
Sbjct: 290 GWLMQLEKKLHSL-QPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFS 348
Query: 3739 KMRARALEECPHPQFKKLVYVLAFFHAVVQ 3768
+ + + P+ + +L ++LA+FHA++Q
Sbjct: 349 SIPVSRICKSPNER-ARLYFLLAWFHAIIQ 377
Score = 45.6 bits (103), Expect = 0.004
Identities = 84/377 (22%), Positives = 140/377 (37%), Gaps = 32/377 (8%)
Query: 3766 VVQVMYGGXXXXXXXXXXXXTYMEEYMGEFLFDKFQPFHFYKDYAFDYVIPPEGERDEYI 3825
+ Q +YGG T++E FD D D +P R+E++
Sbjct: 433 MAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFV 492
Query: 3826 DFIDTLPLANTPEVFGLHPNAEIGYFSQAVREMWGHLIELQPQTSEAGGA------MSRE 3879
+++ LP TP GL NAE + +M ++++Q E A +R
Sbjct: 493 QWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRT 552
Query: 3880 DFIDNIAVDVLSKLPTLYEIW-RVRKQFEMNITPTLVVLLQELERFNRLISRMGS-TLSL 3937
D + + L T W + Q ++ T+ + L RF +MG+ L
Sbjct: 553 DSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQD 612
Query: 3938 LRKALA-------GEIGMDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIART 3990
+R+ LA G+ L + L G LP+ W + W+ F R
Sbjct: 613 VRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERI 672
Query: 3991 KQY--------TDWATVEEPVVIWLSGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVT 4042
KQ + A + + + L GL +PE+Y+ A Q + +W L+ VT
Sbjct: 673 KQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVT 732
Query: 4043 SWVSADEIEERPVTGCYVRGLYLEGARWDVDEGCLKRSHPKVLVTELPIMYIIPI-EFHK 4101
+ A V GL L+GA + + K S + T LP+ + + + +
Sbjct: 733 TSQGA----TLDACSFGVTGLKLQGATCNNN----KLSLSNAISTALPLTQLRWVKQTNT 784
Query: 4102 LKLQNTLRTPVYTTSQR 4118
K + + PVY R
Sbjct: 785 EKKASVVTLPVYLNFTR 801
>L23958-1|AAA16065.1| 141|Homo sapiens dynein heavy chain protein.
Length = 141
Score = 113 bits (273), Expect = 1e-23
Identities = 64/150 (42%), Positives = 82/150 (54%), Gaps = 9/150 (6%)
Query: 1505 LTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDFRAVGQ 1564
LTDR YLT+TQAL +L L LG +V NC E DF+A+G+
Sbjct: 1 LTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGR 60
Query: 1565 ILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSALLMKLKRFTVNTDVLKPSQKFG 1624
I GLCQ GAWGCFDEFNR++ +LS +S Q+QCI+ AL R N + K S
Sbjct: 61 IFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEAL-----REHSNPNYDKTSAPI- 114
Query: 1625 RLKTKRRAGQEIAMDSKVGIFITMNPGYAG 1654
T +++ + + IFITMNPGYAG
Sbjct: 115 ---TCELLNKQVKVSPDMAIFITMNPGYAG 141
>AC013274-1|AAY14776.1| 213|Homo sapiens unknown protein.
Length = 213
Score = 107 bits (256), Expect = 1e-21
Identities = 62/207 (29%), Positives = 102/207 (49%), Gaps = 8/207 (3%)
Query: 3948 MDAVLDNVSYSLFNGQLPQVWRALAPATCKGLGGWMDHFIARTKQYTDWATVEEPVVIWL 4007
M L+ V S+ N ++P++W + + K LG +++ F+AR K W V P V WL
Sbjct: 5 MSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQWYEVGPPPVFWL 64
Query: 4008 SGLHIPESYLIAHVQIACRLYTWPLDRSTQFTKVTSWVSADEIEERPVTGCYVRGLYLEG 4067
SG +++L Q R YT P+D +V + E + P G ++ GL+L+G
Sbjct: 65 SGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEV---MEDKEYKHPPEDGVFIHGLFLDG 121
Query: 4068 ARWDVDEGCLKRSHPKVLVTELPIMYIIPIEFHKLKLQNTLRTPVYTTSQRRNAM----- 4122
A W+ L SHPK+L +P+M++ P + + + + P+Y TS+RR +
Sbjct: 122 ASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLSTTGH 181
Query: 4123 GVGLVFESDLWTTEHCSHWILQGVCLI 4149
V L + + HWI +GV L+
Sbjct: 182 STNFVIAMTLPSDQPKEHWIGRGVALL 208
>AK074178-1|BAB85004.1| 1007|Homo sapiens FLJ00251 protein protein.
Length = 1007
Score = 105 bits (252), Expect = 3e-21
Identities = 120/521 (23%), Positives = 209/521 (40%), Gaps = 45/521 (8%)
Query: 1479 WIRQCTGVFEYGYEYMGLNGRLVITPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXX 1538
WI F Y YEY+G + + L +R L + AL
Sbjct: 328 WIDVLGRSFLYNYEYLGPRLGPLPSLLPERPALVLLLALEEVACGTVLGPNGVGKRAIVN 387
Query: 1539 DLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQC 1598
LA+ALG V+ C ++ + + L G Q GAW ++ +++ +LS + +L
Sbjct: 388 SLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEKVHQLPPGLLSALGQRLGE 447
Query: 1599 IRSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTEL 1658
+ + + NT + P+Q L + +++ G + + A + +
Sbjct: 448 LHHLYAPLYQEASRNTSTIDPTQP-QLLGSSFFEKHHVSVRLGYGCLLVLR---ALSSAV 503
Query: 1659 PESVKALFRPVVCILPDLEMICQISLFSDGFLTAKVLAKKMTVLYKVAREQLS------- 1711
P ++ L RPV LPDL + +++L G A +A +++ + + RE +S
Sbjct: 504 PANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCRL 563
Query: 1712 ---KQSHYDWGLRALTAVLRMAGKLRRDSPGLSEIMVLMRALRDMNHPKF-VFEDVPL-- 1765
KQ D +R L + S E L+ AL + P F + + L
Sbjct: 564 PLLKQILEDT-IRTLNVTKEEPKCQKPRSLAAIEEAALLHAL--LRSPLFSILNGLHLHN 620
Query: 1766 FLGLIKDLFPGLE---CPRVGYPEFNAAVLEVLEKDGYVVLPHQVDKVVQLYETMMTRHC 1822
GL+ LFP + Y V+E L++ G P + + QL + +
Sbjct: 621 LRGLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSRASG 680
Query: 1823 TMLVGPTGGGKTVILHCLVKAQTNLGL----------PTKLTVVNPKACSVIELYGILDP 1872
+L+GP G GKT H L K Q L P ++T + P S E G L+
Sbjct: 681 ILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQEFLGWLEG 740
Query: 1873 VTRDWTDGLYSKIFR---EMNRPAEKNE-------RRYSLFDGDVDALWIENMNSVMDDN 1922
W G++ K+ R + N +K + + + + DG + W++++ ++ +
Sbjct: 741 SC--WHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITCLLSEL 798
Query: 1923 KLLTLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVF 1963
L+L +G++I P LL EV D SP V +V+
Sbjct: 799 PQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVW 839
>AL137619-1|CAB70845.1| 617|Homo sapiens hypothetical protein
protein.
Length = 617
Score = 95.1 bits (226), Expect = 5e-18
Identities = 105/458 (22%), Positives = 189/458 (41%), Gaps = 45/458 (9%)
Query: 1542 KALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRS 1601
+ALG V+ C ++ + + L G Q GAW ++ +++ +LS + +L +
Sbjct: 1 QALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEKVHQLPPGLLSALGQRLGELHH 60
Query: 1602 ALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNPGYAGRTELPES 1661
+ + NT + P+Q L + +++ G + + A + +P +
Sbjct: 61 LYAPLYQEASRNTSTIDPTQP-QLLGSSFFEKHHVSVRLGYGCLLVLR---ALSSAVPAN 116
Query: 1662 VKALFRPVVCILPDLEMICQISLFSDGFLTAKVLAKKMTVLYKVAREQLS---------- 1711
+ L RPV LPDL + +++L G A +A +++ + + RE +S
Sbjct: 117 LHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVSGPLPCRLPLL 176
Query: 1712 KQSHYDWGLRALTAVLRMAGKLRRDSPGLSEIMVLMRALRDMNHPKF-VFEDVPL--FLG 1768
KQ D +R L + S E L+ AL + P F + + L G
Sbjct: 177 KQILEDT-IRTLNVTKEEPKCQKPRSLAAIEEAALLHAL--LRSPLFSILNGLHLHNLRG 233
Query: 1769 LIKDLFPGLE---CPRVGYPEFNAAVLEVLEKDGYVVLPHQVDKVVQLYETMMTRHCTML 1825
L+ LFP + Y V+E L++ G P + + QL + + +L
Sbjct: 234 LLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSRASGILL 293
Query: 1826 VGPTGGGKTVILHCLVKAQTNLGL----------PTKLTVVNPKACSVIELYGILDPVTR 1875
+GP G GKT H L K Q L P ++T + P S E G L+
Sbjct: 294 LGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQEFLGWLEGSC- 352
Query: 1876 DWTDGLYSKIFR---EMNRPAEKNE-------RRYSLFDGDVDALWIENMNSVMDDNKLL 1925
W G++ K+ R + N +K + + + + DG + W++++ ++ + L
Sbjct: 353 -WHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITCLLSELPQL 411
Query: 1926 TLANGERIRLAPYCSLLFEVGDLNYASPATVSRAGMVF 1963
+L +G++I P LL EV D SP V +V+
Sbjct: 412 SLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVW 449
>AJ132086-1|CAA10559.1| 101|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 101
Score = 94.7 bits (225), Expect = 6e-18
Identities = 44/72 (61%), Positives = 53/72 (73%)
Query: 1539 DLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQC 1598
DLAKAL + CVV NC +G+D + +G+ +GL Q GAW CFDEFNRIDI VLSVI+ QL
Sbjct: 9 DLAKALAIQCVVFNCSDGLDCKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLIT 68
Query: 1599 IRSALLMKLKRF 1610
IR+A KL RF
Sbjct: 69 IRNAKAAKLSRF 80
>AJ132088-1|CAA10561.1| 101|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 101
Score = 93.9 bits (223), Expect = 1e-17
Identities = 50/112 (44%), Positives = 68/112 (60%), Gaps = 19/112 (16%)
Query: 1539 DLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQC 1598
DL +ALG+L V NC E MD+++ G I GL Q GAWGCFDEFNRI + VLSV++ Q++
Sbjct: 9 DLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKS 68
Query: 1599 IRSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNP 1650
I+ A+ K + F+ G+EI+++ VGIFITMNP
Sbjct: 69 IQDAIRDKKQWFSF-------------------LGEEISLNPSVGIFITMNP 101
>AJ132087-1|CAA10560.1| 101|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 101
Score = 93.9 bits (223), Expect = 1e-17
Identities = 49/112 (43%), Positives = 65/112 (58%), Gaps = 19/112 (16%)
Query: 1539 DLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQC 1598
DL +ALG++ V NC E MD++++G I GL Q GAWGCFDEFNRI + VLSV++ Q++
Sbjct: 9 DLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKM 68
Query: 1599 IRSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNP 1650
I A+ + KRF G+ I + VGIFITMNP
Sbjct: 69 IHDAIRNRKKRFVF-------------------LGEAITLKPSVGIFITMNP 101
>U83573-1|AAB82762.1| 102|Homo sapiens axonemal dynein heavy chain
isotype3 protein.
Length = 102
Score = 92.3 bits (219), Expect = 3e-17
Identities = 41/80 (51%), Positives = 54/80 (67%)
Query: 1539 DLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQC 1598
DLAKAL + CVV NC +G+D+ A+G+ GL GAW CFDEFNRI++ VLSV++ Q+ C
Sbjct: 13 DLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILC 72
Query: 1599 IRSALLMKLKRFTVNTDVLK 1618
I+ A+ KL F LK
Sbjct: 73 IQRAIQQKLVVFVFEGTELK 92
>Z83799-1|CAB06053.1| 101|Homo sapiens axonemal dynein heavy chain
protein.
Length = 101
Score = 91.9 bits (218), Expect = 4e-17
Identities = 49/113 (43%), Positives = 65/113 (57%), Gaps = 19/113 (16%)
Query: 1539 DLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQC 1598
DL + LG + V NC E MD+++ G I GL Q GAWGCFDEFNRI + VL VI+ Q++C
Sbjct: 8 DLDRPLGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLYVIAVQVKC 67
Query: 1599 IRSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNPG 1651
++ A+ K K+F G+ I++ VGIFITMNPG
Sbjct: 68 VQDAIRAKKKKFNF-------------------LGEIISLVPTVGIFITMNPG 101
>U83570-1|AAB82760.1| 83|Homo sapiens axonemal dynein heavy chain
isotype2 protein.
Length = 83
Score = 88.6 bits (210), Expect = 4e-16
Identities = 37/67 (55%), Positives = 51/67 (76%)
Query: 1544 LGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSAL 1603
LG+ +V NC EG+D++++G++ +GL Q GAWGCFDEFNRI+I VLSV++ Q+ CI SAL
Sbjct: 1 LGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSAL 60
Query: 1604 LMKLKRF 1610
L F
Sbjct: 61 AAGLTHF 67
>U61736-1|AAC50700.1| 80|Homo sapiens dynein heavy chain protein.
Length = 80
Score = 87.0 bits (206), Expect = 1e-15
Identities = 38/80 (47%), Positives = 48/80 (60%)
Query: 1503 TPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDFRAV 1562
TPLTDR YL + AL + L DLAKAL + CVV NC +G+D++ +
Sbjct: 1 TPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMM 60
Query: 1563 GQILAGLCQCGAWGCFDEFN 1582
G+ +GL Q GAWGCFDEFN
Sbjct: 61 GRFFSGLAQSGAWGCFDEFN 80
>BC037496-1|AAH37496.1| 504|Homo sapiens DYNC2H1 protein protein.
Length = 504
Score = 85.8 bits (203), Expect = 3e-15
Identities = 48/122 (39%), Positives = 68/122 (55%), Gaps = 4/122 (3%)
Query: 3650 LGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFLRELEKQLELMTKPHPEYRLWLTTDP 3709
+GQGQ A+ +L+ +G WL L+N HL+VS+L LEK+L + +P +RLWLT +
Sbjct: 1 MGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNTL-QPKDTFRLWLTAEV 59
Query: 3710 TPTFPIGILQRSLK---EPPNGLKLNLRNTYFKMRARALEECPHPQFKKLVYVLAFFHAV 3766
P F +LQ SLK E P GLK NL TY + + + ++ LA+FHA
Sbjct: 60 HPNFTPILLQSSLKITYESPPGLKKNLMRTYESWTPEQISKKDNTHRAHALFSLAWFHAA 119
Query: 3767 VQ 3768
Q
Sbjct: 120 CQ 121
>AK021818-1|BAB13905.1| 553|Homo sapiens protein ( Homo sapiens cDNA
FLJ11756 fis, clone HEMBA1005595, weakly similar to
DYNEIN HEAVY CHAIN, CYTOSOLIC. ).
Length = 553
Score = 85.8 bits (203), Expect = 3e-15
Identities = 48/122 (39%), Positives = 68/122 (55%), Gaps = 4/122 (3%)
Query: 3650 LGQGQEGAALSLLEGAISHGQWLILQNCHLLVSFLRELEKQLELMTKPHPEYRLWLTTDP 3709
+GQGQ A+ +L+ +G WL L+N HL+VS+L LEK+L + +P +RLWLT +
Sbjct: 1 MGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNTL-QPKDTFRLWLTAEV 59
Query: 3710 TPTFPIGILQRSLK---EPPNGLKLNLRNTYFKMRARALEECPHPQFKKLVYVLAFFHAV 3766
P F +LQ SLK E P GLK NL TY + + + ++ LA+FHA
Sbjct: 60 HPNFTPILLQSSLKITYESPPGLKKNLMRTYESWTPEQISKKDNTHRAHALFSLAWFHAA 119
Query: 3767 VQ 3768
Q
Sbjct: 120 CQ 121
>AJ132094-1|CAB46445.1| 83|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 83
Score = 85.4 bits (202), Expect = 4e-15
Identities = 38/72 (52%), Positives = 49/72 (68%)
Query: 1539 DLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQC 1598
DL KAL + VV NC + +DF A+G+ GL GAW CFDEFNRIDI VLSV+S Q+
Sbjct: 6 DLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVSQQITT 65
Query: 1599 IRSALLMKLKRF 1610
I+ A +++RF
Sbjct: 66 IQKAQQQRVERF 77
>Z83803-1|CAB06057.1| 101|Homo sapiens axonemal dynein heavy chain
protein.
Length = 101
Score = 84.2 bits (199), Expect = 9e-15
Identities = 46/113 (40%), Positives = 63/113 (55%), Gaps = 19/113 (16%)
Query: 1539 DLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQC 1598
DL +A+G++ V NC E MD+++ G I GL Q GAW CFDEFNRI + VLSV++ Q++
Sbjct: 8 DLGRAIGIMVYVFNCSEQMDYQSCGNIYKGLAQTGAWACFDEFNRITVEVLSVVAVQVKS 67
Query: 1599 IRSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNPG 1651
++ A+ K F G+ I+ VGIFITMNPG
Sbjct: 68 VQDAIRDKKDTFNF-------------------MGEIISCVPTVGIFITMNPG 101
>Z83806-1|CAB06060.1| 107|Homo sapiens axonemal dynein heavy chain
protein.
Length = 107
Score = 83.0 bits (196), Expect = 2e-14
Identities = 44/113 (38%), Positives = 64/113 (56%), Gaps = 18/113 (15%)
Query: 1539 DLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQC 1598
D+ + LG VV NC + MDFR +G+I GL Q G+WGCFDEFNRI++ VLSV + Q+
Sbjct: 13 DMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYI 72
Query: 1599 IRSALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNPG 1651
+ +A + K+F + G + ++ + G+FITMNPG
Sbjct: 73 VLTARKERKKQFIFSD------------------GDCVDLNPEFGVFITMNPG 107
>U83571-1|AAB82761.1| 89|Homo sapiens axonemal dynein heavy chain
isotype1 protein.
Length = 89
Score = 83.0 bits (196), Expect = 2e-14
Identities = 37/71 (52%), Positives = 48/71 (67%)
Query: 1540 LAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCI 1599
L KAL + VV NC + +DF A+G+ GL GAW CFDEFNRIDI VLSV+S Q+ I
Sbjct: 1 LGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVSQQITTI 60
Query: 1600 RSALLMKLKRF 1610
+ A +++RF
Sbjct: 61 QKAQQQRVERF 71
>AL034345-2|CAI42434.1| 134|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 134
Score = 82.2 bits (194), Expect = 4e-14
Identities = 44/100 (44%), Positives = 60/100 (60%), Gaps = 1/100 (1%)
Query: 1688 GFLTAKVLAKKMTVLYK-VAREQLSKQSHYDWGLRALTAVLRMAGKLRRDSPGLSEIMVL 1746
G+ + L + + + ++ VA +Q HYD+GLR + +VLR G +R P SE+ ++
Sbjct: 33 GYAGRQELPENLKIQFRTVAMMVPDRQVHYDFGLRNILSVLRTLGSQKRARPEDSELSIV 92
Query: 1747 MRALRDMNHPKFVFEDVPLFLGLIKDLFPGLECPRVGYPE 1786
MR LRDMN K V ED PLFL LI DLFPGL+ Y E
Sbjct: 93 MRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAE 132
Score = 55.2 bits (127), Expect = 5e-06
Identities = 23/46 (50%), Positives = 34/46 (73%)
Query: 1633 GQEIAMDSKVGIFITMNPGYAGRTELPESVKALFRPVVCILPDLEM 1678
G + ++ + GIF+TMNPGYAGR ELPE++K FR V ++PD ++
Sbjct: 15 GDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQV 60
>U61735-1|AAC50699.1| 79|Homo sapiens dynein heavy chain protein.
Length = 79
Score = 81.8 bits (193), Expect = 5e-14
Identities = 37/79 (46%), Positives = 45/79 (56%)
Query: 1503 TPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDFRAV 1562
TPLTDR Y+T+ QAL M + D+ + LG VV NC + MDFR +
Sbjct: 1 TPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKDVVVFNCSDQMDFRGL 60
Query: 1563 GQILAGLCQCGAWGCFDEF 1581
G+I GL Q GAWGCFDEF
Sbjct: 61 GRIFKGLAQSGAWGCFDEF 79
>Z83804-1|CAB06058.1| 101|Homo sapiens axonemal dynein heavy chain
protein.
Length = 101
Score = 80.2 bits (189), Expect = 1e-13
Identities = 45/110 (40%), Positives = 59/110 (53%), Gaps = 19/110 (17%)
Query: 1542 KALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRS 1601
KAL + VV NC + +DF A+G+ GL GAW CFDEFNRIDI VLSV++ Q+ I+
Sbjct: 11 KALAIQTVVFNCSDLLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQK 70
Query: 1602 ALLMKLKRFTVNTDVLKPSQKFGRLKTKRRAGQEIAMDSKVGIFITMNPG 1651
A +++RF G EI + +FITMNPG
Sbjct: 71 AQQQRVERFMFE-------------------GVEIPLVPSYAVFITMNPG 101
>U61737-1|AAC50701.1| 77|Homo sapiens dynein heavy chain protein.
Length = 77
Score = 77.4 bits (182), Expect = 1e-12
Identities = 37/77 (48%), Positives = 43/77 (55%)
Query: 1503 TPLTDRIYLTITQALTMQLXXXXXXXXXXXXXXXXXDLAKALGLLCVVTNCGEGMDFRAV 1562
TPLTDR YLT+TQAL +L L LG +V NC E DF+A+
Sbjct: 1 TPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAM 60
Query: 1563 GQILAGLCQCGAWGCFD 1579
G+I GLCQ GAWGCFD
Sbjct: 61 GRIFVGLCQVGAWGCFD 77
>BC117303-1|AAI17304.1| 1021|Homo sapiens dynein heavy chain domain 1
protein.
Length = 1021
Score = 77.0 bits (181), Expect = 1e-12
Identities = 92/432 (21%), Positives = 164/432 (37%), Gaps = 24/432 (5%)
Query: 3284 VINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANKSLLSGLEDSLLRELATST 3343
V++ + ++ LE+Q+L ++ E +LE + + L I + E+ LL L
Sbjct: 15 VLDLGLNMEILEEQMLHEILCREYPELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQN 74
Query: 3344 GNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRDGYRPVAKRGSILFFVLSD 3403
+ + + + K ++ E E L YRPV G + LS
Sbjct: 75 PKRQKPAKFLRNIVRAQGKLCQLRAHCEELEGQKLQEMVLWAPYRPVVWHGMAMVKALSQ 134
Query: 3404 MAGVNSMYQYSLSSYLDVFSFSLRKAMPNVI-----LVKRLKNIIDMLTKNVYDYGCTGI 3458
+ + ++ S ++L V +L P I L L + LT+ + T +
Sbjct: 135 LQNLLPLFCMSPENWLAVTKQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTAL 194
Query: 3459 FERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLEKSARSSPA------PWMPAQG 3512
L + L Q+ S+ + G + + S P W+ +
Sbjct: 195 GLTQVPLVGALGALALLQATGKASELERLALWPGLAASPSTVHSKPVSDVARPAWLGPKA 254
Query: 3513 WQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLKPFELLMLL 3572
W + L + PF L + WQ + + P E L + L+L
Sbjct: 255 WHECEML--ELLPPFVGLCASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSLLQKLILW 312
Query: 3573 RCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPGSDPTADL- 3631
R R + + AL D+ T +G + + M + + P++ +L P P+A L
Sbjct: 313 RVLRPECLAGALADFTTSLLGRP-LDENTYAPTMPFKHSQATQPMLILLPPPGHPSATLH 371
Query: 3632 -----MKLADRCGFGGGKFKYLSLGQ---GQEGAALSLLEGAISHGQWLILQNCHLLVSF 3683
KLA + G + + ++LG +S L A+ G WL+L NCHL+ +
Sbjct: 372 PLTVIQKLAAKYQQGQKQLQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMPHW 431
Query: 3684 LRE-LEKQLELM 3694
+E L+ LEL+
Sbjct: 432 PKELLQLLLELL 443
>BC117301-1|AAI17302.1| 1021|Homo sapiens dynein heavy chain domain 1
protein.
Length = 1021
Score = 77.0 bits (181), Expect = 1e-12
Identities = 92/432 (21%), Positives = 164/432 (37%), Gaps = 24/432 (5%)
Query: 3284 VINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANKSLLSGLEDSLLRELATST 3343
V++ + ++ LE+Q+L ++ E +LE + + L I + E+ LL L
Sbjct: 15 VLDLGLNMEILEEQMLHEILCREYPELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQN 74
Query: 3344 GNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRDGYRPVAKRGSILFFVLSD 3403
+ + + + K ++ E E L YRPV G + LS
Sbjct: 75 PKRQKPAKFLRNIVRAQGKLCQLRAHCEELEGQKLQEMVLWAPYRPVVWHGMAMVKALSQ 134
Query: 3404 MAGVNSMYQYSLSSYLDVFSFSLRKAMPNVI-----LVKRLKNIIDMLTKNVYDYGCTGI 3458
+ + ++ S ++L V +L P I L L + LT+ + T +
Sbjct: 135 LQNLLPLFCMSPENWLAVTKQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTAL 194
Query: 3459 FERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLEKSARSSPA------PWMPAQG 3512
L + L Q+ S+ + G + + S P W+ +
Sbjct: 195 GLTQVPLVGALGALALLQATGKASELERLALWPGLAASPSTVHSKPVSDVARPAWLGPKA 254
Query: 3513 WQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLKPFELLMLL 3572
W + L + PF L + WQ + + P E L + L+L
Sbjct: 255 WHECEML--ELLPPFVGLCASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSLLQKLILW 312
Query: 3573 RCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPGSDPTADL- 3631
R R + + AL D+ T +G + + M + + P++ +L P P+A L
Sbjct: 313 RVLRPECLAGALADFTTSLLGRP-LDENTYAPTMPFKHSQATQPMLILLPPPGHPSATLH 371
Query: 3632 -----MKLADRCGFGGGKFKYLSLGQ---GQEGAALSLLEGAISHGQWLILQNCHLLVSF 3683
KLA + G + + ++LG +S L A+ G WL+L NCHL+ +
Sbjct: 372 PLTVIQKLAAKYQQGQKQLQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMPHW 431
Query: 3684 LRE-LEKQLELM 3694
+E L+ LEL+
Sbjct: 432 PKELLQLLLELL 443
>AK057314-1|BAB71423.1| 1021|Homo sapiens protein ( Homo sapiens cDNA
FLJ32752 fis, clone TESTI2001661, weakly similar to
DYNEIN BETA CHAIN, FLAGELLAR OUTER ARM. ).
Length = 1021
Score = 77.0 bits (181), Expect = 1e-12
Identities = 92/432 (21%), Positives = 164/432 (37%), Gaps = 24/432 (5%)
Query: 3284 VINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANKSLLSGLEDSLLRELATST 3343
V++ + ++ LE+Q+L ++ E +LE + + L I + E+ LL L
Sbjct: 15 VLDLGLNMEILEEQMLHEILCREYPELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQN 74
Query: 3344 GNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEKLRDGYRPVAKRGSILFFVLSD 3403
+ + + + K ++ E E L YRPV G + LS
Sbjct: 75 PKRQKPAKFLRNIVRAQGKLCQLRAHCEELEGQKLQEMVLWAPYRPVVWHGMAMVKALSQ 134
Query: 3404 MAGVNSMYQYSLSSYLDVFSFSLRKAMPNVI-----LVKRLKNIIDMLTKNVYDYGCTGI 3458
+ + ++ S ++L V +L P I L L + LT+ + T +
Sbjct: 135 LQNLLPLFCMSPENWLAVTKQALDSMKPREINHGEDLASHLLQLRAHLTRQLLGSTVTAL 194
Query: 3459 FERHKLLFSFQMDIKLEQSEDNVSQAQLDFFIKGNVSLEKSARSSPA------PWMPAQG 3512
L + L Q+ S+ + G + + S P W+ +
Sbjct: 195 GLTQVPLVGALGALALLQATGKASELERLALWPGLAASPSTVHSKPVSDVARPAWLGPKA 254
Query: 3513 WQDIMKLSSDFPDPFATLPDDITKFLEEWQEWFDSDTPESAEIPNNYREKLKPFELLMLL 3572
W + L + PF L + WQ + + P E L + L+L
Sbjct: 255 WHECEML--ELLPPFVGLCASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSLLQKLILW 312
Query: 3573 RCFRVDRIYRALTDYITVTMGEEYITPPVISLDMIVEQTTPFTPVVFILSPGSDPTADL- 3631
R R + + AL D+ T +G + + M + + P++ +L P P+A L
Sbjct: 313 RVLRPECLAGALADFTTSLLGRP-LDENTYAPTMPFKHSQATQPMLILLPPPGHPSATLH 371
Query: 3632 -----MKLADRCGFGGGKFKYLSLGQ---GQEGAALSLLEGAISHGQWLILQNCHLLVSF 3683
KLA + G + + ++LG +S L A+ G WL+L NCHL+ +
Sbjct: 372 PLTVIQKLAAKYQQGQKQLQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCHLMPHW 431
Query: 3684 LRE-LEKQLELM 3694
+E L+ LEL+
Sbjct: 432 PKELLQLLLELL 443
>AJ132090-1|CAA10563.1| 57|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 57
Score = 75.8 bits (178), Expect = 3e-12
Identities = 32/53 (60%), Positives = 39/53 (73%)
Query: 1539 DLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSV 1591
D+ + LG VV NC + MDFR +G+I GL Q G+WGCFDEFNRID+ VLSV
Sbjct: 3 DMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSV 55
>AJ132091-1|CAA10564.1| 57|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 57
Score = 74.1 bits (174), Expect = 1e-11
Identities = 31/53 (58%), Positives = 39/53 (73%)
Query: 1539 DLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSV 1591
D+ + LG VV NC + MDFR +G+I GL Q G+WGCFDEFNRI++ VLSV
Sbjct: 3 DMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSV 55
>AB231765-1|BAE46899.1| 94|Homo sapiens hypothetical protein
protein.
Length = 94
Score = 73.7 bits (173), Expect = 1e-11
Identities = 35/93 (37%), Positives = 54/93 (58%)
Query: 1760 FEDVPLFLGLIKDLFPGLECPRVGYPEFNAAVLEVLEKDGYVVLPHQVDKVVQLYETMMT 1819
F D F LIKD+FPG++ V Y E +AA+ +V E+ Y ++P+Q+ K ++LYE +
Sbjct: 2 FTDCTRFDALIKDVFPGIKLKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQLCQ 61
Query: 1820 RHCTMLVGPTGGGKTVILHCLVKAQTNLGLPTK 1852
R ++VGP+G GK+ + L A G K
Sbjct: 62 RMGVVIVGPSGAGKSTLWRMLRAALCKTGKVVK 94
>U61739-1|AAC50703.1| 55|Homo sapiens dynein heavy chain protein.
Length = 55
Score = 67.7 bits (158), Expect = 8e-10
Identities = 27/44 (61%), Positives = 33/44 (75%)
Query: 1539 DLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFN 1582
DLAKAL + CVV NC +G+D+ A+G+ GL GAWGCFDEFN
Sbjct: 12 DLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWGCFDEFN 55
>U61740-1|AAC50704.1| 54|Homo sapiens dynein heavy chain protein.
Length = 54
Score = 65.7 bits (153), Expect = 3e-09
Identities = 27/44 (61%), Positives = 32/44 (72%)
Query: 1539 DLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFN 1582
DL +ALG+L V NC E MD+++ G I GL Q GAWGCFDEFN
Sbjct: 11 DLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFN 54
>AL162738-1|CAI95641.1| 207|Homo sapiens novel protein protein.
Length = 207
Score = 64.9 bits (151), Expect = 6e-09
Identities = 41/131 (31%), Positives = 64/131 (48%), Gaps = 28/131 (21%)
Query: 2167 IIQQMNFSSRTSSMDVQRNLESVVEKRTKDTFGPPVGKRMLVFIDDMNMPIVSHNNQCVP 2226
++ +NFS+ ++ + + + +RTKDT G P R+L+FIDDMNMP+
Sbjct: 105 VVSTINFSTNVTAAKTKEMILKKLIRRTKDTLGAPKNNRILIFIDDMNMPV--------- 155
Query: 2227 SLCSTRVQTLLSHPLVDTYGTQQPIALLKLLFERKGFYDRGKDLNWKNLKDIGFLAAMGK 2286
D YG Q P+ L++ L + G YD K+ WKN++D+ +AA
Sbjct: 156 ---------------SDMYGAQPPLELIRQLLDLGGVYDTEKN-TWKNIQDLSIVAACVP 199
Query: 2287 AGGGRNDVDPR 2297
ND+ PR
Sbjct: 200 V---VNDISPR 207
>AJ132093-1|CAB46444.1| 67|Homo sapiens axonemal dynein, heavy chain
protein.
Length = 67
Score = 64.9 bits (151), Expect = 6e-09
Identities = 25/49 (51%), Positives = 36/49 (73%)
Query: 1555 EGMDFRAVGQILAGLCQCGAWGCFDEFNRIDISVLSVISTQLQCIRSAL 1603
+G+D+ A+G+ GL CGAW CFDEFNRID+ VLSV++ Q+ I+ +
Sbjct: 1 DGLDYLALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGI 49
>U61738-1|AAC50702.1| 55|Homo sapiens dynein heavy chain protein.
Length = 55
Score = 61.3 bits (142), Expect = 7e-08
Identities = 25/44 (56%), Positives = 30/44 (68%)
Query: 1539 DLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFN 1582
DL KAL + VV NC + +DF A+G+ GL GAWGCFDEFN
Sbjct: 12 DLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWGCFDEFN 55
>U61741-1|AAC50705.1| 55|Homo sapiens dynein heavy chain protein.
Length = 55
Score = 58.0 bits (134), Expect = 7e-07
Identities = 26/44 (59%), Positives = 31/44 (70%)
Query: 1539 DLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWGCFDEFN 1582
DLAK+LG CVV NC E +D++ V + GL Q GA GCFDEFN
Sbjct: 12 DLAKSLGKHCVVFNCFEDLDYKIVRKFFFGLVQSGALGCFDEFN 55
>AK125990-1|BAC86379.1| 1205|Homo sapiens protein ( Homo sapiens cDNA
FLJ44002 fis, clone TESTI4022873. ).
Length = 1205
Score = 54.8 bits (126), Expect = 6e-06
Identities = 55/294 (18%), Positives = 128/294 (43%), Gaps = 17/294 (5%)
Query: 798 VQQMTITAEVKYRGMQEIFHMLKQHGINVTDEDLQFAKSLEASWGS--LYQTSLFRGNTL 855
+ + + E + + + + ++ + N++ +D K + ++W S L Q L + +
Sbjct: 874 IPERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFN-DKWIASNWPSKILGQIELVQQQHV 932
Query: 856 EQTKEKFSKLNVVEISNFLKELDDFVEKFDNEGPATVEDDMDRGLLLMEEYGKYIDELES 915
E +EKF K+ +++ +NF ++L+ + G ++ ++ R + E + +L+
Sbjct: 933 ED-EEKFRKIQIMDQNNFQEKLEGL--QLVVAG-FSIHVEISRAHEIANEVRRVKKQLKD 988
Query: 916 RKKMLQA---AEQLFDNPLADFSNFNRTKADYSAMDQIYKIYKAQKNAREVWAKTLWVNL 972
+++ E++F P+ ++ +R ++ ++ E W +
Sbjct: 989 CQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAI 1048
Query: 973 NPQALVDGIEQFFKEYRKLPKIVR----LSSTGLMLDLKMKQFKGVVPLMVSLKNEAMRE 1028
+ + L + + FK K K + L + ++++FK +PL+ L+N MR
Sbjct: 1049 DAEQLEKNVVEAFKTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRI 1108
Query: 1029 RHWKELMAKTGQDFDMSPD-RFTLENMFAMELHKYQDVAEEIVNHAIKELAIER 1081
RHW+ L + + ++ P T M L + + ++ A KE AIE+
Sbjct: 1109 RHWETLSNQI--NINVRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQ 1160
>U83574-1|AAB82763.1| 50|Homo sapiens axonemal dynein heavy chain
isotype3b protein.
Length = 50
Score = 52.8 bits (121), Expect = 3e-05
Identities = 21/37 (56%), Positives = 27/37 (72%)
Query: 1539 DLAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAW 1575
DLAKAL CVV NC +G+D++A+G+ GL Q GAW
Sbjct: 13 DLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAW 49
>U83569-1|AAB82759.1| 37|Homo sapiens axonemal dynein heavy chain
isotype 11 protein.
Length = 37
Score = 48.4 bits (110), Expect = 5e-04
Identities = 19/37 (51%), Positives = 26/37 (70%)
Query: 1540 LAKALGLLCVVTNCGEGMDFRAVGQILAGLCQCGAWG 1576
L +ALG++ V NC E MD++++G I GL Q GAWG
Sbjct: 1 LGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWG 37
>BC034225-1|AAH34225.1| 872|Homo sapiens DNAH2 protein protein.
Length = 872
Score = 46.8 bits (106), Expect = 0.002
Identities = 63/287 (21%), Positives = 110/287 (38%), Gaps = 22/287 (7%)
Query: 2 WHDLYKET-RRNIELSGKGARWEFDQPLLFTRTDYIGTVARDLGDIIQVLIDFER----- 55
W D Y + + +I+ S +G W DQ +F + D +DL ++ F R
Sbjct: 430 WKDHYVQAVQMHIQFSSRG--WVLDQTSIFAQVDAFVQRCKDLIEVCDCQYHFARWEDGK 487
Query: 56 ------IFGLELKSIISDPTQIDDVRKRVKNLVYPIRTVDFSVFVFDNKENWDVIMGDFW 109
FG + I + +I+D+ KNL + +R V + N W F
Sbjct: 488 QGPLPCFFGAQGPQITRNLLEIEDIFH--KNL-HTLRAVRGGILDVKNT-CWHEDYNKFR 543
Query: 110 NEVRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLSTK-FDLVMRQFI 168
++ LE +N I +F +R + +L F +RE+I+R K DL M F
Sbjct: 544 AGIKDLEVMTQNLITSAFELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYM-LFN 602
Query: 169 KEITAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMKQPIMKFQKVSELNECEQKK 228
E+ + + R +K P L +G W L ++ + + L K
Sbjct: 603 SELALVNRE--RNKKWPDLEPYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGK 660
Query: 229 EAFLQYKAFSKIIKEYEDTKYKEWVQDASLFCDNMMKKNILKVVFKK 275
E+ Y+ + I ++EW C + +L++ +K
Sbjct: 661 ESVHTYQQMVQAIDGLVRKTFQEWTSSLDKDCIRRLDTPLLRISQEK 707
>BC112284-1|AAI12285.1| 566|Homo sapiens dynein, axonemal, heavy
chain like 1 protein.
Length = 566
Score = 44.8 bits (101), Expect = 0.007
Identities = 45/250 (18%), Positives = 107/250 (42%), Gaps = 14/250 (5%)
Query: 22 WEFDQPLLFTRTDYIGTVARDLGDIIQVLIDFERIFGLELKSIISDPTQIDDVRKRVKNL 81
WEF L F+R + + + ++ + I+F ++ +EL + + + + R+ +
Sbjct: 108 WEFPSSLAFSRINSFFQRIQTIEELYKTAIEFLKLEKIELGGVRGN--LLGSLVTRIYDE 165
Query: 82 VYPIRTVDFSVFVFD----NKENWDVIMGDFWNEVRYLEDEAKNYINQSFGNLRSSEEAL 137
V+ + V F+ +D N+D DF +++ L+ Q F + + +
Sbjct: 166 VFELVKV-FADCKYDPLDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSA 224
Query: 138 TVLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEITAIEDKFTRYRK-----NPPLL-RNH 191
+L R I +++ ++ +++ F E+ + + N PL+ +N
Sbjct: 225 KLLYMCGGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNM 284
Query: 192 PPVAGAISWARALFNKMKQPIMKFQKVSE-LNECEQKKEAFLQYKAFSKIIKEYEDTKYK 250
PPVAG + W+ L +++ + + V + + K + +Y ++++ + + Y+
Sbjct: 285 PPVAGQLKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQ 344
Query: 251 EWVQDASLFC 260
+WV C
Sbjct: 345 QWVAGVDQDC 354
Score = 39.9 bits (89), Expect = 0.19
Identities = 28/142 (19%), Positives = 66/142 (46%), Gaps = 4/142 (2%)
Query: 378 NFDKDLFLVIHEAELME-QLGFDVPSNVRDVAMQKSRLFYELEALSKIIAKYNKNASSLS 436
NF K L V+ E + + Q ++P + + + + L I+ YN+ + +
Sbjct: 375 NFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLELIVGWYNEIKTIVK 434
Query: 437 PSETYLMKRHLLDMERHILPGLTRITWTALGINDYIKDITKGENSLQAVYQQLKMVEKEI 496
E L+K L ++ +L T + W G+ YI+++ + ++LQ +++ ++ I
Sbjct: 435 AVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQ---NRMQKAKQNI 491
Query: 497 QFLINQLQEFDLFPVVRPKNYK 518
+ + ++++ P+ K+ K
Sbjct: 492 EGISQAMKDWSANPLFERKDNK 513
>BC105107-1|AAI05108.1| 566|Homo sapiens dynein, axonemal, heavy
chain like 1 protein.
Length = 566
Score = 44.8 bits (101), Expect = 0.007
Identities = 45/250 (18%), Positives = 107/250 (42%), Gaps = 14/250 (5%)
Query: 22 WEFDQPLLFTRTDYIGTVARDLGDIIQVLIDFERIFGLELKSIISDPTQIDDVRKRVKNL 81
WEF L F+R + + + ++ + I+F ++ +EL + + + + R+ +
Sbjct: 108 WEFPSSLAFSRINSFFQRIQTIEELYKTAIEFLKLEKIELGGVRGN--LLGSLVTRIYDE 165
Query: 82 VYPIRTVDFSVFVFD----NKENWDVIMGDFWNEVRYLEDEAKNYINQSFGNLRSSEEAL 137
V+ + V F+ +D N+D DF +++ L+ Q F + + +
Sbjct: 166 VFELVKV-FADCKYDPLDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSA 224
Query: 138 TVLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEITAIEDKFTRYRK-----NPPLL-RNH 191
+L R I +++ ++ +++ F E+ + + N PL+ +N
Sbjct: 225 KLLYMCGGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNM 284
Query: 192 PPVAGAISWARALFNKMKQPIMKFQKVSE-LNECEQKKEAFLQYKAFSKIIKEYEDTKYK 250
PPVAG + W+ L +++ + + V + + K + +Y ++++ + + Y+
Sbjct: 285 PPVAGQLKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQ 344
Query: 251 EWVQDASLFC 260
+WV C
Sbjct: 345 QWVAGVDQDC 354
Score = 39.9 bits (89), Expect = 0.19
Identities = 28/142 (19%), Positives = 66/142 (46%), Gaps = 4/142 (2%)
Query: 378 NFDKDLFLVIHEAELME-QLGFDVPSNVRDVAMQKSRLFYELEALSKIIAKYNKNASSLS 436
NF K L V+ E + + Q ++P + + + + L I+ YN+ + +
Sbjct: 375 NFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLELIVGWYNEIKTIVK 434
Query: 437 PSETYLMKRHLLDMERHILPGLTRITWTALGINDYIKDITKGENSLQAVYQQLKMVEKEI 496
E L+K L ++ +L T + W G+ YI+++ + ++LQ +++ ++ I
Sbjct: 435 AVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQ---NRMQKAKQNI 491
Query: 497 QFLINQLQEFDLFPVVRPKNYK 518
+ + ++++ P+ K+ K
Sbjct: 492 EGISQAMKDWSANPLFERKDNK 513
>AK097776-1|BAC05170.1| 566|Homo sapiens protein ( Homo sapiens
cDNA FLJ40457 fis, clone TESTI2041730, weakly similar to
DYNEIN BETA CHAIN, CILIARY. ).
Length = 566
Score = 44.8 bits (101), Expect = 0.007
Identities = 45/250 (18%), Positives = 107/250 (42%), Gaps = 14/250 (5%)
Query: 22 WEFDQPLLFTRTDYIGTVARDLGDIIQVLIDFERIFGLELKSIISDPTQIDDVRKRVKNL 81
WEF L F+R + + + ++ + I+F ++ +EL + + + + R+ +
Sbjct: 108 WEFPSSLAFSRINSFFQRIQTIEELYKTAIEFLKLEKIELGGVRGN--LLGSLVTRIYDE 165
Query: 82 VYPIRTVDFSVFVFD----NKENWDVIMGDFWNEVRYLEDEAKNYINQSFGNLRSSEEAL 137
V+ + V F+ +D N+D DF +++ L+ Q F + + +
Sbjct: 166 VFELVKV-FADCKYDPLDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSA 224
Query: 138 TVLLKFLEFDTRESIRRQLSTKFDLVMRQFIKEITAIEDKFTRYRK-----NPPLL-RNH 191
+L R I +++ ++ +++ F E+ + + N PL+ +N
Sbjct: 225 KLLYMCGGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNM 284
Query: 192 PPVAGAISWARALFNKMKQPIMKFQKVSE-LNECEQKKEAFLQYKAFSKIIKEYEDTKYK 250
PPVAG + W+ L +++ + + V + + K + +Y ++++ + + Y+
Sbjct: 285 PPVAGQLKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQ 344
Query: 251 EWVQDASLFC 260
+WV C
Sbjct: 345 QWVAGVDQDC 354
Score = 39.9 bits (89), Expect = 0.19
Identities = 27/142 (19%), Positives = 65/142 (45%), Gaps = 4/142 (2%)
Query: 378 NFDKDLFLVIHEAELME-QLGFDVPSNVRDVAMQKSRLFYELEALSKIIAKYNKNASSLS 436
NF K L V+ E + + Q ++P + + + + L I+ YN+ + ++
Sbjct: 375 NFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLELIVGWYNEIKTIVN 434
Query: 437 PSETYLMKRHLLDMERHILPGLTRITWTALGINDYIKDITKGENSLQAVYQQLKMVEKEI 496
E L+K L ++ +L T + W G+ YI+++ L ++ +++ ++ I
Sbjct: 435 AVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEV---REILHNLHNRMQKAKQNI 491
Query: 497 QFLINQLQEFDLFPVVRPKNYK 518
+ + ++++ P+ K+ K
Sbjct: 492 EGISQAMKDWSANPLFERKDNK 513
>DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein.
Length = 2479
Score = 40.7 bits (91), Expect = 0.11
Identities = 42/164 (25%), Positives = 69/164 (42%), Gaps = 15/164 (9%)
Query: 3219 LFQDVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPNFRMYLTTKLANPQFNPAA 3278
L + NE DP++ V N KVE + + E+ L KL N Q +
Sbjct: 291 LLKSKNEEDDPIMVAV---NAKVEEWKLILSSKDDEIIEYQQMLHNLREKLKNAQLD--- 344
Query: 3279 YAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANKSLLSGLEDSLLRE 3338
A N QG++++ + + L EQ E E N ++ L++ L R
Sbjct: 345 ---ADKSNVMALQQGIQERDSQIKM------LTEQVEQYTKEMEKNTCIIEDLKNELQRN 395
Query: 3339 LATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEK 3382
ST + ++++ +TL+ K K E ELAEA ++ +K
Sbjct: 396 KGASTLSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDK 439
>BC043398-1|AAH43398.1| 805|Homo sapiens CEP290 protein protein.
Length = 805
Score = 40.7 bits (91), Expect = 0.11
Identities = 42/164 (25%), Positives = 69/164 (42%), Gaps = 15/164 (9%)
Query: 3219 LFQDVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPNFRMYLTTKLANPQFNPAA 3278
L + NE DP++ V N KVE + + E+ L KL N Q +
Sbjct: 291 LLKSKNEEDDPIMVAV---NAKVEEWKLILSSKDDEIIEYQQMLHNLREKLKNAQLD--- 344
Query: 3279 YAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANKSLLSGLEDSLLRE 3338
A N QG++++ + + L EQ E E N ++ L++ L R
Sbjct: 345 ---ADKSNVMALQQGIQERDSQIKM------LTEQVEQYTKEMEKNTCIIEDLKNELQRN 395
Query: 3339 LATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEK 3382
ST + ++++ +TL+ K K E ELAEA ++ +K
Sbjct: 396 KGASTLSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDK 439
>AK023677-1|BAB14636.1| 574|Homo sapiens protein ( Homo sapiens cDNA
FLJ13615 fis, clone PLACE1010896, weakly similar to NUF1
PROTEIN. ).
Length = 574
Score = 40.7 bits (91), Expect = 0.11
Identities = 42/164 (25%), Positives = 69/164 (42%), Gaps = 15/164 (9%)
Query: 3219 LFQDVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPNFRMYLTTKLANPQFNPAA 3278
L + NE DP++ V N KVE + + E+ L KL N Q +
Sbjct: 291 LLKSKNEEDDPIMVAV---NAKVEEWKLILSSKDDEIIEYQQMLHNLREKLKNAQLD--- 344
Query: 3279 YAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANKSLLSGLEDSLLRE 3338
A N QG++++ + + L EQ E E N ++ L++ L R
Sbjct: 345 ---ADKSNVMALQQGIQERDSQIKM------LTEQVEQYTKEMEKNTCIIEDLKNELQRN 395
Query: 3339 LATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEK 3382
ST + ++++ +TL+ K K E ELAEA ++ +K
Sbjct: 396 KGASTLSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDK 439
>AF317887-1|AAK01919.1| 589|Homo sapiens monoclonal antibody 3H11
antigen protein.
Length = 589
Score = 40.7 bits (91), Expect = 0.11
Identities = 42/164 (25%), Positives = 69/164 (42%), Gaps = 15/164 (9%)
Query: 3219 LFQDVNEYIDPVVDNVLEKNIKVESGRTFVMLGSTEVDYDPNFRMYLTTKLANPQFNPAA 3278
L + NE DP++ V N KVE + + E+ L KL N Q +
Sbjct: 233 LLKSKNEEDDPIMVAV---NAKVEEWKLILSSKDDEIIEYQQMLHNLREKLKNAQLD--- 286
Query: 3279 YAKAVVINYTVTVQGLEDQLLSVVVRAERSDLEEQRESLIIETSANKSLLSGLEDSLLRE 3338
A N QG++++ + + L EQ E E N ++ L++ L R
Sbjct: 287 ---ADKSNVMALQQGIQERDSQIKM------LTEQVEQYTKEMEKNTCIIEDLKNELQRN 337
Query: 3339 LATSTGNMLDNVELVNTLENTKSKAAEVMEKLELAEATTKDIEK 3382
ST + ++++ +TL+ K K E ELAEA ++ +K
Sbjct: 338 KGASTLSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDK 381
>BC004130-1|AAH04130.1| 446|Homo sapiens calcium binding and
coiled-coil domain 2 protein.
Length = 446
Score = 39.1 bits (87), Expect = 0.33
Identities = 25/92 (27%), Positives = 47/92 (51%)
Query: 3014 LASLNREIDRLQKTLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRW 3073
LA ++ +L++T++ + TAM ++QEL +E + +RL + + + L +++R
Sbjct: 272 LAEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNALQRQKERL 331
Query: 3074 TEDLAALYVEQSRLIGNCLLATSFLSYTGPFS 3105
+ L E SRL+ L + L Y P S
Sbjct: 332 EGENDLLKRENSRLLSYMGLDFNSLPYQVPTS 363
>AK025632-1|BAB15196.1| 720|Homo sapiens protein ( Homo sapiens cDNA:
FLJ21979 fis, clone HEP06065. ).
Length = 720
Score = 37.9 bits (84), Expect = 0.77
Identities = 22/73 (30%), Positives = 36/73 (49%)
Query: 3310 LEEQRESLIIETSANKSLLSGLEDSLLRELATSTGNMLDNVELVNTLENTKSKAAEVMEK 3369
L EQ E E N ++ L++ L R ST + ++++ +TL+ K K E
Sbjct: 2 LTEQVEQYTKEMEKNTCIIEDLKNELQRNKGASTLSQQTHMKIQSTLDILKEKTKEAERT 61
Query: 3370 LELAEATTKDIEK 3382
ELAEA ++ +K
Sbjct: 62 AELAEADAREKDK 74
>U22897-1|AAA75297.1| 446|Homo sapiens NDP52 protein.
Length = 446
Score = 37.5 bits (83), Expect = 1.0
Identities = 24/92 (26%), Positives = 46/92 (50%)
Query: 3014 LASLNREIDRLQKTLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRW 3073
L ++ +L++T++ + TAM ++QEL +E + +RL + + + L +++R
Sbjct: 272 LTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNALQRQKERL 331
Query: 3074 TEDLAALYVEQSRLIGNCLLATSFLSYTGPFS 3105
+ L E SRL+ L + L Y P S
Sbjct: 332 EGENDLLKRENSRLLSYMGLDFNSLPYQVPTS 363
>CR456763-1|CAG33044.1| 446|Homo sapiens NDP52 protein.
Length = 446
Score = 37.5 bits (83), Expect = 1.0
Identities = 24/92 (26%), Positives = 46/92 (50%)
Query: 3014 LASLNREIDRLQKTLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRW 3073
L ++ +L++T++ + TAM ++QEL +E + +RL + + + L +++R
Sbjct: 272 LTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNALQRQKERL 331
Query: 3074 TEDLAALYVEQSRLIGNCLLATSFLSYTGPFS 3105
+ L E SRL+ L + L Y P S
Sbjct: 332 EGENDLLKRENSRLLSYMGLDFNSLPYQVPTS 363
>BC015893-1|AAH15893.1| 446|Homo sapiens calcium binding and
coiled-coil domain 2 protein.
Length = 446
Score = 37.5 bits (83), Expect = 1.0
Identities = 24/92 (26%), Positives = 46/92 (50%)
Query: 3014 LASLNREIDRLQKTLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRW 3073
L ++ +L++T++ + TAM ++QEL +E + +RL + + + L +++R
Sbjct: 272 LTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNALQRQKERL 331
Query: 3074 TEDLAALYVEQSRLIGNCLLATSFLSYTGPFS 3105
+ L E SRL+ L + L Y P S
Sbjct: 332 EGENDLLKRENSRLLSYMGLDFNSLPYQVPTS 363
>AK223227-1|BAD96947.1| 446|Homo sapiens nuclear domain 10 protein
variant protein.
Length = 446
Score = 37.5 bits (83), Expect = 1.0
Identities = 24/92 (26%), Positives = 46/92 (50%)
Query: 3014 LASLNREIDRLQKTLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRW 3073
L ++ +L++T++ + TAM ++QEL +E + +RL + + + L +++R
Sbjct: 272 LTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNALQRQKERL 331
Query: 3074 TEDLAALYVEQSRLIGNCLLATSFLSYTGPFS 3105
+ L E SRL+ L + L Y P S
Sbjct: 332 EGENDLLKRENSRLLSYMGLDFNSLPYQVPTS 363
>AK222666-1|BAD96386.1| 429|Homo sapiens nuclear domain 10 protein
variant protein.
Length = 429
Score = 37.5 bits (83), Expect = 1.0
Identities = 24/92 (26%), Positives = 46/92 (50%)
Query: 3014 LASLNREIDRLQKTLDGLNNRYETAMMRRQELQEETDLMMRRLVAADKLMSGLSSEQKRW 3073
L ++ +L++T++ + TAM ++QEL +E + +RL + + + L +++R
Sbjct: 272 LTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNALQRQKERL 331
Query: 3074 TEDLAALYVEQSRLIGNCLLATSFLSYTGPFS 3105
+ L E SRL+ L + L Y P S
Sbjct: 332 EGENDLLKRENSRLLSYMGLDFNSLPYQVPTS 363
>BC044830-1|AAH44830.1| 258|Homo sapiens chromosome 10 open reading
frame 96 protein.
Length = 258
Score = 34.7 bits (76), Expect = 7.2
Identities = 29/113 (25%), Positives = 51/113 (45%), Gaps = 8/113 (7%)
Query: 831 LQFAKSLEASWGSLYQTSLFRGNTLEQTKEKFSKLNVVEISNFLKELDDFVEKFDNEGPA 890
LQ K+ E + Y N L QT E K + E F+KE+ D F+N+
Sbjct: 66 LQLLKAHENALEKQYSEITNHRNMLLQTFEAIKKQMIEEEDKFIKEITD----FNNDYEI 121
Query: 891 TVEDDMDRGLLLMEEYGKYIDELESRKKMLQAAEQLFDNPLADFSNFNRTKAD 943
T + R LL+ E I +LE++ ML++ + ++ + + + K++
Sbjct: 122 TKK----RELLMKENVKIEISDLENQANMLKSEMKSMEHDSSQLNELQKQKSE 170
>X69086-1|CAA48829.1| 3433|Homo sapiens utrophin (dystrophin related
protein) protein.
Length = 3433
Score = 34.3 bits (75), Expect = 9.5
Identities = 34/143 (23%), Positives = 67/143 (46%), Gaps = 16/143 (11%)
Query: 98 KENWDVIMGDFWNEVRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLS 157
K+ +D + G WN+++ L + + + + LR+ E TV+ K+++ ++ + +Q +
Sbjct: 987 KQEFDDVQGK-WNKLKVLVSKDLHLLEEIALTLRAFEADSTVIEKWMD-GVKDFLMKQQA 1044
Query: 158 TKFD--LVMRQ------FIKEITAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMK 209
+ D + RQ F+ EI IE ++ LR+ PVAG +W + +
Sbjct: 1045 AQGDDAGLQRQLDQCSAFVNEIETIESSLKNMKEIETNLRS-GPVAGIKTWVQTRLGDYQ 1103
Query: 210 QPIMKFQK-----VSELNECEQK 227
+ K K S L+E ++K
Sbjct: 1104 TQLEKLSKEIATQKSRLSESQEK 1126
>AL590704-1|CAI10894.1| 3433|Homo sapiens utrophin (homologous to
dystrophin) protein.
Length = 3433
Score = 34.3 bits (75), Expect = 9.5
Identities = 34/143 (23%), Positives = 67/143 (46%), Gaps = 16/143 (11%)
Query: 98 KENWDVIMGDFWNEVRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLS 157
K+ +D + G WN+++ L + + + + LR+ E TV+ K+++ ++ + +Q +
Sbjct: 987 KQEFDDVQGK-WNKLKVLVSKDLHLLEEIALTLRAFEADSTVIEKWMD-GVKDFLMKQQA 1044
Query: 158 TKFD--LVMRQ------FIKEITAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMK 209
+ D + RQ F+ EI IE ++ LR+ PVAG +W + +
Sbjct: 1045 AQGDDAGLQRQLDQCSAFVNEIETIESSLKNMKEIETNLRS-GPVAGIKTWVQTRLGDYQ 1103
Query: 210 QPIMKFQK-----VSELNECEQK 227
+ K K S L+E ++K
Sbjct: 1104 TQLEKLSKEIATQKSRLSESQEK 1126
>AL590488-1|CAI16497.1| 3433|Homo sapiens utrophin (homologous to
dystrophin) protein.
Length = 3433
Score = 34.3 bits (75), Expect = 9.5
Identities = 34/143 (23%), Positives = 67/143 (46%), Gaps = 16/143 (11%)
Query: 98 KENWDVIMGDFWNEVRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLS 157
K+ +D + G WN+++ L + + + + LR+ E TV+ K+++ ++ + +Q +
Sbjct: 987 KQEFDDVQGK-WNKLKVLVSKDLHLLEEIALTLRAFEADSTVIEKWMD-GVKDFLMKQQA 1044
Query: 158 TKFD--LVMRQ------FIKEITAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMK 209
+ D + RQ F+ EI IE ++ LR+ PVAG +W + +
Sbjct: 1045 AQGDDAGLQRQLDQCSAFVNEIETIESSLKNMKEIETNLRS-GPVAGIKTWVQTRLGDYQ 1103
Query: 210 QPIMKFQK-----VSELNECEQK 227
+ K K S L+E ++K
Sbjct: 1104 TQLEKLSKEIATQKSRLSESQEK 1126
>AL513475-1|CAI13032.1| 3433|Homo sapiens utrophin (homologous to
dystrophin) protein.
Length = 3433
Score = 34.3 bits (75), Expect = 9.5
Identities = 34/143 (23%), Positives = 67/143 (46%), Gaps = 16/143 (11%)
Query: 98 KENWDVIMGDFWNEVRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLS 157
K+ +D + G WN+++ L + + + + LR+ E TV+ K+++ ++ + +Q +
Sbjct: 987 KQEFDDVQGK-WNKLKVLVSKDLHLLEEIALTLRAFEADSTVIEKWMD-GVKDFLMKQQA 1044
Query: 158 TKFD--LVMRQ------FIKEITAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMK 209
+ D + RQ F+ EI IE ++ LR+ PVAG +W + +
Sbjct: 1045 AQGDDAGLQRQLDQCSAFVNEIETIESSLKNMKEIETNLRS-GPVAGIKTWVQTRLGDYQ 1103
Query: 210 QPIMKFQK-----VSELNECEQK 227
+ K K S L+E ++K
Sbjct: 1104 TQLEKLSKEIATQKSRLSESQEK 1126
>AL513184-1|CAI40502.1| 3433|Homo sapiens utrophin (homologous to
dystrophin) protein.
Length = 3433
Score = 34.3 bits (75), Expect = 9.5
Identities = 34/143 (23%), Positives = 67/143 (46%), Gaps = 16/143 (11%)
Query: 98 KENWDVIMGDFWNEVRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLS 157
K+ +D + G WN+++ L + + + + LR+ E TV+ K+++ ++ + +Q +
Sbjct: 987 KQEFDDVQGK-WNKLKVLVSKDLHLLEEIALTLRAFEADSTVIEKWMD-GVKDFLMKQQA 1044
Query: 158 TKFD--LVMRQ------FIKEITAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMK 209
+ D + RQ F+ EI IE ++ LR+ PVAG +W + +
Sbjct: 1045 AQGDDAGLQRQLDQCSAFVNEIETIESSLKNMKEIETNLRS-GPVAGIKTWVQTRLGDYQ 1103
Query: 210 QPIMKFQK-----VSELNECEQK 227
+ K K S L+E ++K
Sbjct: 1104 TQLEKLSKEIATQKSRLSESQEK 1126
>AL357149-1|CAI40388.1| 3433|Homo sapiens utrophin (homologous to
dystrophin) protein.
Length = 3433
Score = 34.3 bits (75), Expect = 9.5
Identities = 34/143 (23%), Positives = 67/143 (46%), Gaps = 16/143 (11%)
Query: 98 KENWDVIMGDFWNEVRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLS 157
K+ +D + G WN+++ L + + + + LR+ E TV+ K+++ ++ + +Q +
Sbjct: 987 KQEFDDVQGK-WNKLKVLVSKDLHLLEEIALTLRAFEADSTVIEKWMD-GVKDFLMKQQA 1044
Query: 158 TKFD--LVMRQ------FIKEITAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMK 209
+ D + RQ F+ EI IE ++ LR+ PVAG +W + +
Sbjct: 1045 AQGDDAGLQRQLDQCSAFVNEIETIESSLKNMKEIETNLRS-GPVAGIKTWVQTRLGDYQ 1103
Query: 210 QPIMKFQK-----VSELNECEQK 227
+ K K S L+E ++K
Sbjct: 1104 TQLEKLSKEIATQKSRLSESQEK 1126
>AL024474-2|CAI23353.1| 3433|Homo sapiens utrophin (homologous to
dystrophin) protein.
Length = 3433
Score = 34.3 bits (75), Expect = 9.5
Identities = 34/143 (23%), Positives = 67/143 (46%), Gaps = 16/143 (11%)
Query: 98 KENWDVIMGDFWNEVRYLEDEAKNYINQSFGNLRSSEEALTVLLKFLEFDTRESIRRQLS 157
K+ +D + G WN+++ L + + + + LR+ E TV+ K+++ ++ + +Q +
Sbjct: 987 KQEFDDVQGK-WNKLKVLVSKDLHLLEEIALTLRAFEADSTVIEKWMD-GVKDFLMKQQA 1044
Query: 158 TKFD--LVMRQ------FIKEITAIEDKFTRYRKNPPLLRNHPPVAGAISWARALFNKMK 209
+ D + RQ F+ EI IE ++ LR+ PVAG +W + +
Sbjct: 1045 AQGDDAGLQRQLDQCSAFVNEIETIESSLKNMKEIETNLRS-GPVAGIKTWVQTRLGDYQ 1103
Query: 210 QPIMKFQK-----VSELNECEQK 227
+ K K S L+E ++K
Sbjct: 1104 TQLEKLSKEIATQKSRLSESQEK 1126
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.137 0.408
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 566,878,564
Number of Sequences: 224733
Number of extensions: 23400138
Number of successful extensions: 51746
Number of sequences better than 10.0: 140
Number of HSP's better than 10.0 without gapping: 127
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 50158
Number of HSP's gapped (non-prelim): 811
length of query: 4153
length of database: 73,234,838
effective HSP length: 105
effective length of query: 4048
effective length of database: 49,637,873
effective search space: 200934109904
effective search space used: 200934109904
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 75 (34.3 bits)
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