Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001836-TA|BGIBMGA001836-PA|IPR002048|Calcium-binding
EF-hand, IPR013032|EGF-like region, IPR001881|EGF-like
calcium-binding, IPR006210|EGF, IPR009030|Growth factor, receptor,
IPR013091|EGF calcium-binding, IPR003367|Thrombospondin type 3 repeat,
IPR008859|Thrombospondin, C-terminal
(804 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L32137-1|AAA57253.1| 757|Homo sapiens matrix protein protein. 582 e-165
AB086984-1|BAC53888.1| 757|Homo sapiens cartilage oligomeric ma... 582 e-165
L38969-1|AAC41762.1| 956|Homo sapiens thrombospondin 3 protein. 580 e-165
AL713999-15|CAI95084.1| 956|Homo sapiens thrombospondin 3 protein. 580 e-165
AK223278-1|BAD96998.1| 956|Homo sapiens thrombospondin 3 precur... 580 e-165
BC113847-1|AAI13848.1| 956|Homo sapiens thrombospondin 3, precu... 579 e-164
BC125092-1|AAI25093.1| 757|Homo sapiens cartilage oligomeric ma... 577 e-164
BC110847-1|AAI10848.1| 757|Homo sapiens cartilage oligomeric ma... 577 e-164
AC003107-1|AAB86501.1| 817|Homo sapiens COMP_HUMAN protein. 577 e-164
AK223216-1|BAD96936.1| 757|Homo sapiens cartilage oligomeric ma... 575 e-163
Z19585-1|CAA79635.1| 961|Homo sapiens thrombospondin-4 protein. 565 e-160
BC050456-1|AAH50456.1| 961|Homo sapiens thrombospondin 4 protein. 565 e-160
AY566253-1|AAS66982.1| 961|Homo sapiens thrombospondin 4 protein. 565 e-160
BC018786-1|AAH18786.1| 592|Homo sapiens Similar to thrombospond... 551 e-156
BC113846-1|AAI13847.1| 485|Homo sapiens THBS3 protein protein. 484 e-136
X14787-1|CAA32889.1| 1170|Homo sapiens precursor polypeptide (AA... 481 e-135
X04665-1|CAA28370.1| 1170|Homo sapiens protein ( Human mRNA for ... 481 e-135
AB209912-1|BAD93149.1| 1225|Homo sapiens thrombospondin 1 precur... 481 e-135
L12350-1|AAA03703.1| 1172|Homo sapiens thrombospondin 2 protein. 464 e-130
BX322234-1|CAI23645.1| 1172|Homo sapiens thrombospondin 2 protein. 464 e-130
BX641023-1|CAE46014.1| 430|Homo sapiens hypothetical protein pr... 409 e-113
AF023268-6|AAC51818.1| 736|Homo sapiens thrombospondin3 protein. 272 2e-72
M99425-1|AAB59366.1| 143|Homo sapiens thrombospondin protein. 195 4e-49
AK027344-1|BAB55049.1| 741|Homo sapiens protein ( Homo sapiens ... 91 2e-17
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 87 2e-16
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 87 2e-16
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 87 2e-16
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 87 2e-16
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 87 2e-16
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 87 2e-16
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 87 2e-16
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 87 2e-16
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 87 2e-16
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 87 3e-16
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl... 86 5e-16
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl... 86 5e-16
AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein va... 86 5e-16
Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein. 85 1e-15
S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growt... 85 1e-15
BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming gro... 85 1e-15
AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming gro... 85 1e-15
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein. 83 3e-15
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein. 83 3e-15
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 83 3e-15
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 83 3e-15
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso... 83 3e-15
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop... 83 3e-15
M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein. 81 2e-14
BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming gro... 81 2e-14
AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth fac... 81 2e-14
AC019127-1|AAY24260.1| 697|Homo sapiens unknown protein. 81 2e-14
AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming gro... 81 2e-14
D86566-1|BAA13116.1| 955|Homo sapiens notch related protein pro... 80 3e-14
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 80 4e-14
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso... 80 4e-14
Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein. 78 1e-13
AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein. 78 1e-13
AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein. 78 1e-13
AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein. 78 1e-13
AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein. 77 2e-13
AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming gro... 76 4e-13
AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming gro... 76 4e-13
Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding p... 75 1e-12
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein. 75 1e-12
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein. 75 1e-12
AY358892-1|AAQ89251.1| 723|Homo sapiens DLL1 protein. 74 2e-12
AL078605-2|CAB89569.1| 723|Homo sapiens delta-like 1 (Drosophil... 74 2e-12
AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein. 74 2e-12
AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein pr... 74 2e-12
AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein. 74 2e-12
AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precurs... 73 5e-12
AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precurso... 73 5e-12
AL513325-3|CAH72584.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 73 5e-12
AL513325-2|CAM17208.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 73 5e-12
AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 73 5e-12
AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 73 5e-12
AL136322-4|CAI16646.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 73 5e-12
AL136322-3|CAM23328.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 73 5e-12
AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1 (alt... 73 5e-12
AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein. 73 5e-12
AB208923-1|BAD92160.1| 441|Homo sapiens crumbs homolog 1 isofor... 73 5e-12
X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein. 72 9e-12
BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein. 72 9e-12
AY130459-1|AAN05436.1| 1231|Homo sapiens fibulin 2 protein. 72 9e-12
AY130458-1|AAN05435.1| 1231|Homo sapiens fibulin 2 protein. 72 9e-12
AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form ... 71 2e-11
AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form ... 71 2e-11
AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form ... 71 2e-11
AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein. 71 2e-11
AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein. 71 2e-11
AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein. 71 2e-11
AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein. 71 2e-11
AL133553-4|CAI17860.1| 240|Homo sapiens protein ( Human DNA seq... 71 2e-11
AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein. 71 2e-11
AF525689-1|AAN77133.1| 988|Homo sapiens signal peptide-CUB-EGF-... 70 3e-11
Z99756-1|CAI18854.1| 988|Homo sapiens protein ( Human DNA seque... 70 4e-11
Z82214-3|CAI21674.1| 988|Homo sapiens protein ( Human DNA seque... 70 4e-11
X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein. 69 5e-11
U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein. 69 5e-11
L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein. 69 5e-11
AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein. 69 5e-11
AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein. 69 5e-11
AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein. 69 5e-11
U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jag... 69 7e-11
U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein. 69 7e-11
U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jag... 69 7e-11
BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille synd... 69 7e-11
BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille synd... 69 7e-11
BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille synd... 69 7e-11
AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille synd... 69 7e-11
AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein. 69 7e-11
AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein J... 69 7e-11
AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein. 69 7e-11
U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein. 69 9e-11
AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital... 69 9e-11
BC106950-1|AAI06951.1| 685|Homo sapiens delta-like 4 (Drosophil... 67 2e-10
AY358894-1|AAQ89253.1| 685|Homo sapiens DLL4 protein. 67 2e-10
AF279305-1|AAF81912.1| 653|Homo sapiens delta 4 protein. 67 2e-10
AF253468-1|AAF76427.1| 685|Homo sapiens notch ligand DLL4 protein. 67 2e-10
AB043894-1|BAB18581.1| 685|Homo sapiens Delta-4 protein. 67 2e-10
AB036931-1|BAB16085.1| 685|Homo sapiens notch ligand delta-2 pr... 67 2e-10
BC008761-1|AAH08761.2| 743|Homo sapiens LTBP3 protein protein. 66 4e-10
AK160380-1|BAD18723.1| 1055|Homo sapiens FLJ00344 protein protein. 66 4e-10
AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein. 66 4e-10
AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming gro... 66 4e-10
BC052263-1|AAH52263.2| 992|Homo sapiens signal peptide, CUB dom... 66 5e-10
Z97832-1|CAI20187.1| 993|Homo sapiens protein ( Human DNA seque... 66 6e-10
AY639608-1|AAU08347.1| 993|Homo sapiens signal peptide, CUB and... 66 6e-10
AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic fact... 66 6e-10
AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic fact... 66 6e-10
AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 66 6e-10
AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 66 6e-10
AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic fact... 66 6e-10
AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 66 6e-10
AF452494-1|AAN76808.1| 993|Homo sapiens CUB and EGF containing ... 66 6e-10
AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein. 66 6e-10
AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein. 66 6e-10
AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitami... 66 6e-10
AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12 re... 66 6e-10
Z98047-1|CAI19628.1| 703|Homo sapiens fibulin 1 protein. 65 1e-09
Z95331-3|CAI41717.1| 703|Homo sapiens fibulin 1 protein. 65 1e-09
X53743-1|CAA37772.1| 683|Homo sapiens fibulin-1 C protein. 65 1e-09
X53742-1|CAA37771.1| 601|Homo sapiens fibulin-1 B protein. 65 1e-09
X53741-1|CAA37770.1| 566|Homo sapiens fibulin-1 A protein. 65 1e-09
U01244-1|AAB17099.1| 703|Homo sapiens fibulin-1D protein. 65 1e-09
AL021391-3|CAI18930.1| 703|Homo sapiens fibulin 1 protein. 65 1e-09
AK075566-1|BAC11705.1| 638|Homo sapiens protein ( Homo sapiens ... 65 1e-09
AF217999-1|AAG17241.1| 495|Homo sapiens unknown protein. 65 1e-09
AF126110-1|AAK37822.1| 703|Homo sapiens fibulin-1 isoform D pre... 65 1e-09
AB208840-1|BAD92077.1| 830|Homo sapiens fibrillin 1 variant pro... 64 1e-09
X62009-1|CAB56757.1| 754|Homo sapiens fibrillin 5 protein. 64 2e-09
BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein. 64 2e-09
AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive sequ... 64 2e-09
AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant... 64 2e-09
BC022497-1|AAH22497.1| 683|Homo sapiens fibulin 1 protein. 63 3e-09
AY358336-1|AAQ88702.1| 509|Homo sapiens DFLL295 protein. 63 3e-09
AY311388-1|AAP74958.1| 2551|Homo sapiens FEX2 protein. 62 6e-09
AK074051-1|BAB84877.1| 1736|Homo sapiens FLJ00122 protein protein. 62 6e-09
AK024503-1|BAB15793.1| 1192|Homo sapiens FLJ00112 protein protein. 62 6e-09
AJ295695-1|CAC82105.1| 2551|Homo sapiens stabilin-2 protein. 62 6e-09
AB052958-1|BAC15608.1| 2551|Homo sapiens FELE-2 protein. 62 6e-09
AK123000-1|BAC85516.1| 1176|Homo sapiens 3 (HIVEP3). protein. 62 1e-08
D89629-1|BAB46925.1| 815|Homo sapiens cerebral protein-12 protein. 61 1e-08
D83018-1|BAA11681.1| 816|Homo sapiens nel-related protein 2 pro... 61 1e-08
BC020544-1|AAH20544.1| 816|Homo sapiens NELL2 protein protein. 61 1e-08
AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2 p... 61 1e-08
AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 61 1e-08
AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 61 1e-08
AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 61 1e-08
AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 61 1e-08
AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein. 61 1e-08
AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein. 61 1e-08
AY227444-1|AAO39681.1| 1416|Homo sapiens hyaluronan receptor for... 61 2e-08
BC127263-1|AAI27264.1| 363|Homo sapiens SCUBE1 protein protein. 60 2e-08
AK131562-1|BAD18695.1| 867|Homo sapiens protein ( Homo sapiens ... 60 4e-08
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 59 5e-08
BC000218-1|AAH00218.1| 618|Homo sapiens delta-like 3 (Drosophil... 59 7e-08
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 59 7e-08
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 59 7e-08
AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 59 7e-08
AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 59 7e-08
AK131282-1|BAD18457.1| 872|Homo sapiens protein ( Homo sapiens ... 59 7e-08
AF241373-1|AAF62542.1| 618|Homo sapiens DLL3 protein precursor ... 59 7e-08
AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein. 59 7e-08
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 59 7e-08
AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein p... 58 9e-08
AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand f... 58 9e-08
AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand f... 58 9e-08
AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand f... 58 9e-08
AK092062-1|BAC03798.1| 880|Homo sapiens protein ( Homo sapiens ... 58 9e-08
AK075302-1|BAC11535.1| 587|Homo sapiens protein ( Homo sapiens ... 58 9e-08
AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens ... 58 9e-08
AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein. 58 9e-08
BC038587-1|AAH38587.1| 553|Homo sapiens EGF-like-domain, multip... 58 2e-07
AY358333-1|AAQ88699.1| 338|Homo sapiens EGFL6 protein. 58 2e-07
AK075214-1|BAC11477.1| 553|Homo sapiens protein ( Homo sapiens ... 58 2e-07
AJ245671-1|CAB92132.1| 554|Homo sapiens hypothetical protein pr... 58 2e-07
AF186084-1|AAF27812.1| 553|Homo sapiens epidermal growth factor... 58 2e-07
DQ309460-1|ABC26875.1| 231|Homo sapiens delta-like 1 protein. 57 2e-07
BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein. 57 2e-07
BC050675-1|AAH50675.1| 353|Homo sapiens cysteine-rich with EGF-... 57 2e-07
BC014015-1|AAH14015.1| 383|Homo sapiens delta-like 1 homolog (D... 57 2e-07
BC013197-1|AAH13197.1| 383|Homo sapiens delta-like 1 homolog (D... 57 2e-07
BC007741-1|AAH07741.1| 383|Homo sapiens delta-like 1 homolog (D... 57 2e-07
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 57 3e-07
AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 57 3e-07
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 57 3e-07
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 57 3e-07
Z12172-1|CAA78163.1| 383|Homo sapiens putative homeotic protein... 56 4e-07
U15979-1|AAA75364.1| 382|Homo sapiens dlk protein. 56 4e-07
U57523-1|AAB06946.1| 446|Homo sapiens protein ( Human nel homol... 56 5e-07
D83017-1|BAA11680.1| 810|Homo sapiens nel-related protein protein. 56 5e-07
D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein pro... 56 5e-07
DQ470680-1|ABF06672.1| 373|Homo sapiens CRELD2-zeta protein. 56 5e-07
DQ470678-1|ABF06670.1| 353|Homo sapiens CRELD2-delta protein. 56 5e-07
BC096102-1|AAH96102.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 56 5e-07
BC096101-1|AAH96101.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 56 5e-07
BC069674-1|AAH69674.1| 810|Homo sapiens nel-like 1, precursor p... 56 5e-07
AY358355-1|AAQ88721.1| 353|Homo sapiens RLPR185 protein. 56 5e-07
X87241-1|CAA60685.1| 4590|Homo sapiens homologue of Drosophila F... 56 7e-07
X62008-1|CAB56534.1| 517|Homo sapiens fibrillin 15 protein. 56 7e-07
U03877-1|AAA65590.1| 387|Homo sapiens extracellular protein pro... 55 9e-07
BC098561-1|AAH98561.1| 493|Homo sapiens EGF-containing fibulin-... 55 9e-07
BC014410-1|AAH14410.1| 493|Homo sapiens EGF-containing fibulin-... 55 9e-07
AY004330-1|AAK11491.1| 493|Homo sapiens EGF-containing fibulin-... 55 9e-07
AB209212-1|BAD92449.1| 418|Homo sapiens EGF-containing fibulin-... 55 9e-07
D86425-1|BAA13087.1| 1376|Homo sapiens osteonidogen protein. 55 1e-06
DQ217942-1|ABB70739.1| 886|Homo sapiens EGF-like module contain... 55 1e-06
BC059395-1|AAH59395.1| 821|Homo sapiens EMR1 protein protein. 55 1e-06
AJ223500-1|CAA11418.1| 1375|Homo sapiens nidogen-2 protein. 55 1e-06
AB065918-1|BAC06133.1| 929|Homo sapiens seven transmembrane hel... 55 1e-06
AB009799-1|BAA24112.1| 1376|Homo sapiens osteonidogen protein. 55 1e-06
D87433-1|BAA13377.2| 2589|Homo sapiens KIAA0246 protein protein. 54 2e-06
DQ786774-1|ABG91068.1| 2570|Homo sapiens FEX1 protein. 54 2e-06
BC027939-1|AAH27939.1| 600|Homo sapiens SNED1 protein protein. 54 2e-06
AJ295142-1|CAC82720.1| 652|Homo sapiens C1q receptor protein pr... 54 2e-06
AJ275213-1|CAB61827.1| 2570|Homo sapiens stabilin-1 protein. 54 2e-06
AB052956-1|BAC15606.1| 2570|Homo sapiens FELE-1 protein. 54 2e-06
X81479-1|CAA57232.1| 886|Homo sapiens EMR1 protein. 54 2e-06
U94333-1|AAB53110.1| 652|Homo sapiens C1qR(p) protein. 54 2e-06
U77493-1|AAB19224.1| 263|Homo sapiens Notch2 protein. 54 2e-06
BC028075-1|AAH28075.1| 652|Homo sapiens CD93 molecule protein. 54 2e-06
AL118508-1|CAC00597.1| 652|Homo sapiens complement component 1,... 54 2e-06
AB209895-1|BAD93132.1| 671|Homo sapiens complement component 1,... 54 2e-06
BC035608-1|AAH35608.1| 969|Homo sapiens NID2 protein protein. 54 3e-06
AK126775-1|BAC86684.1| 952|Homo sapiens protein ( Homo sapiens ... 54 3e-06
BC111690-1|AAI11691.1| 807|Homo sapiens SCUBE2 protein protein. 53 5e-06
BC035784-1|AAH35784.1| 439|Homo sapiens hypothetical protein FL... 53 5e-06
AK131552-1|BAD18686.1| 682|Homo sapiens protein ( Homo sapiens ... 53 5e-06
AK123039-1|BAC85521.1| 971|Homo sapiens protein ( Homo sapiens ... 53 5e-06
AK094759-1|BAC04416.1| 439|Homo sapiens protein ( Homo sapiens ... 53 5e-06
AJ400877-1|CAB92285.1| 999|Homo sapiens CEGP1 protein protein. 53 5e-06
AC092645-2|AAY14854.1| 439|Homo sapiens unknown protein. 53 5e-06
X04571-1|CAA28240.1| 1207|Homo sapiens protein ( Human mRNA for ... 52 6e-06
BC113461-1|AAI13462.1| 1207|Homo sapiens epidermal growth factor... 52 6e-06
BC093731-1|AAH93731.1| 1207|Homo sapiens epidermal growth factor... 52 6e-06
AY506357-1|AAR84237.1| 1152|Homo sapiens truncated epidermal gro... 52 6e-06
AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domai... 52 6e-06
AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domai... 52 6e-06
AC010895-1|AAY14669.1| 320|Homo sapiens unknown protein. 52 6e-06
AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein pr... 52 6e-06
AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein. 52 6e-06
U77914-1|AAC50909.1| 263|Homo sapiens soluble protein Jagged pr... 52 1e-05
AF193055-1|AAG22483.1| 474|Homo sapiens unknown protein. 52 1e-05
BC126986-1|AAI26987.1| 393|Homo sapiens FLJ37440 protein protein. 51 2e-05
AL645608-12|CAI15575.2| 2045|Homo sapiens agrin protein. 51 2e-05
AF016903-1|AAC39776.1| 2026|Homo sapiens agrin precursor protein. 51 2e-05
AB191264-1|BAD52440.1| 2045|Homo sapiens agrin protein. 51 2e-05
AB052957-1|BAC15607.1| 803|Homo sapiens soluble form FELE-1 pro... 50 3e-05
BC053656-1|AAH53656.1| 470|Homo sapiens EDIL3 protein protein. 50 4e-05
AF054502-1|AAC39882.1| 669|Homo sapiens latent transforming gro... 50 4e-05
BC126313-1|AAI26314.1| 1044|Homo sapiens MEGF11 protein protein. 49 6e-05
BC117419-1|AAI17420.1| 1044|Homo sapiens MEGF11 protein protein. 49 6e-05
AL834326-1|CAD38994.1| 626|Homo sapiens hypothetical protein pr... 49 6e-05
AB058677-1|BAB47410.1| 969|Homo sapiens MEGF11 protein (KIAA178... 49 6e-05
U15981-1|AAA75365.1| 310|Homo sapiens dlk protein. 48 1e-04
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly... 48 1e-04
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog... 48 1e-04
DQ126100-1|AAZ38943.1| 212|Homo sapiens brevideltin protein. 48 2e-04
DQ017081-1|AAY40461.1| 315|Homo sapiens secredeltin protein. 48 2e-04
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog... 48 2e-04
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog... 48 2e-04
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h... 47 2e-04
AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ ... 47 2e-04
AF160476-1|AAF82398.1| 897|Homo sapiens CD44-like precursor FEL... 47 2e-04
Y00692-1|CAA68687.1| 676|Homo sapiens preproprotein S protein. 47 3e-04
M57853-1|AAA60357.1| 676|Homo sapiens S protein protein. 47 3e-04
M36564-1|AAA60180.1| 650|Homo sapiens PROS1 protein. 47 3e-04
M15036-1|AAA36479.1| 676|Homo sapiens protein ( Human vitamin K... 47 3e-04
BC015801-1|AAH15801.1| 676|Homo sapiens PROS1 protein protein. 47 3e-04
AY308744-1|AAP45054.1| 497|Homo sapiens protein S (alpha) protein. 47 3e-04
AL138836-3|CAC22313.2| 602|Homo sapiens multiple EGF-like-domai... 47 3e-04
AB011542-1|BAA32470.1| 375|Homo sapiens MEGF9 protein. 47 3e-04
X82245-1|CAA57709.1| 1246|Homo sapiens nidogen protein. 46 4e-04
M30269-1|AAA59932.1| 1247|Homo sapiens nidogen protein. 46 4e-04
M27445-1|AAA57261.1| 581|Homo sapiens nidogen protein. 46 4e-04
AL139161-2|CAI23422.1| 1247|Homo sapiens nidogen 1 protein. 46 4e-04
AL122018-2|CAI22681.1| 1247|Homo sapiens nidogen 1 protein. 46 4e-04
U70313-1|AAC02649.1| 125|Homo sapiens integrin binding protein ... 46 5e-04
AL359813-8|CAI23223.1| 377|Homo sapiens EGF-like-domain, multip... 46 5e-04
D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein. 45 0.001
BC039143-1|AAH39143.1| 740|Homo sapiens FAT2 protein protein. 45 0.001
AL390252-1|CAI13170.1| 2923|Homo sapiens cadherin, EGF LAG seven... 45 0.001
AL117551-1|CAB55988.1| 511|Homo sapiens hypothetical protein pr... 45 0.001
AF522196-1|AAN45861.1| 870|Homo sapiens scavenger receptor type... 45 0.001
AF234887-1|AAG00080.1| 2923|Homo sapiens FLAMINGO 1 protein. 45 0.001
AF231022-1|AAF61928.1| 4349|Homo sapiens protocadherin Fat 2 pro... 45 0.001
AB177851-1|BAD66829.1| 573|Homo sapiens KIAA0811 splice variant... 45 0.001
AB160984-1|BAD08246.1| 1123|Homo sapiens KIAA0811 protein protein. 45 0.001
AB065955-1|BAC06168.1| 2923|Homo sapiens seven transmembrane hel... 45 0.001
AB052951-1|BAC53753.1| 866|Homo sapiens SRECRP-1 protein. 45 0.001
AB024433-1|BAD93345.1| 866|Homo sapiens NSR1 protein. 45 0.001
AB011535-1|BAA32463.1| 573|Homo sapiens MEGF1 protein. 45 0.001
DQ470679-1|ABF06671.1| 402|Homo sapiens CRELD2-epsilon protein. 45 0.001
CR457140-1|CAG33421.1| 448|Homo sapiens FBLN5 protein. 45 0.001
BC105633-1|AAI05634.1| 757|Homo sapiens tumor endothelial marke... 45 0.001
BC104484-1|AAI04485.1| 757|Homo sapiens tumor endothelial marke... 45 0.001
BC051340-1|AAH51340.1| 757|Homo sapiens CD248 molecule, endosia... 45 0.001
BC022280-1|AAH22280.1| 448|Homo sapiens fibulin 5 protein. 45 0.001
AY358898-1|AAQ89257.1| 448|Homo sapiens FBLN5 protein. 45 0.001
AJ295846-1|CAC34381.1| 757|Homo sapiens endosialin protein prot... 45 0.001
AJ133490-1|CAB38568.1| 448|Homo sapiens fibulin-5 protein. 45 0.001
AF279142-1|AAG00867.1| 757|Homo sapiens tumor endothelial marke... 45 0.001
AF112152-1|AAD41768.1| 448|Homo sapiens developmental arteries ... 45 0.001
CR541934-1|CAG46732.1| 443|Homo sapiens EFEMP2 protein. 44 0.002
BC096103-1|AAH96103.1| 763|Homo sapiens NELL1 protein protein. 44 0.002
BC096100-1|AAH96100.1| 763|Homo sapiens NELL1 protein protein. 44 0.002
BC010456-1|AAH10456.1| 443|Homo sapiens EGF-containing fibulin-... 44 0.002
AY358899-1|AAQ89258.1| 443|Homo sapiens EFEMP2 protein. 44 0.002
AJ132819-1|CAA10791.2| 443|Homo sapiens fibulin-4 protein. 44 0.002
AF109121-1|AAF65188.1| 443|Homo sapiens EGF-containing fibulin-... 44 0.002
AB209448-1|BAD92685.1| 1241|Homo sapiens nidogen (enactin) varia... 44 0.002
AB076400-1|BAB86868.1| 1097|Homo sapiens fat3 protein. 44 0.002
AB030655-1|BAA92880.1| 443|Homo sapiens mutant p53 binding prot... 44 0.002
S78569-1|AAB34635.1| 1816|Homo sapiens laminin alpha 4 chain pro... 44 0.002
S77512-1|AAB34682.2| 1798|Homo sapiens laminin beta 2 chain prot... 44 0.003
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 44 0.003
BC035009-1|AAH35009.1| 737|Homo sapiens delta/notch-like EGF re... 44 0.003
AL356104-4|CAH72941.1| 1037|Homo sapiens novel protein similar t... 44 0.003
AL158169-5|CAH70011.1| 1037|Homo sapiens novel protein similar t... 44 0.003
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 44 0.003
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 44 0.003
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 44 0.003
X05495-1|CAA29045.1| 575|Homo sapiens thrombomodulin protein. 43 0.004
M16552-1|AAB59508.1| 575|Homo sapiens THBD protein. 43 0.004
J02973-1|AAA61175.1| 575|Homo sapiens THBD protein. 43 0.004
D00210-1|BAA00149.1| 575|Homo sapiens thrombomodulin precursor ... 43 0.004
BC110320-1|AAI10321.1| 383|Homo sapiens EGF-like-domain, multip... 43 0.004
BC063620-1|AAH63620.1| 488|Homo sapiens AGRN protein protein. 43 0.004
BC053357-1|AAH53357.1| 575|Homo sapiens thrombomodulin protein. 43 0.004
BC035602-1|AAH35602.2| 575|Homo sapiens thrombomodulin protein. 43 0.004
BC024766-1|AAH24766.2| 454|Homo sapiens DNER protein protein. 43 0.004
BC007649-1|AAH07649.1| 488|Homo sapiens AGRN protein protein. 43 0.004
AY358891-1|AAQ89250.1| 737|Homo sapiens QPRR262 protein. 43 0.004
AY358126-1|AAQ88493.1| 383|Homo sapiens PSGC2903 protein. 43 0.004
AL359813-9|CAI23224.1| 383|Homo sapiens EGF-like-domain, multip... 43 0.004
AL359813-6|CAI23221.1| 288|Homo sapiens EGF-like-domain, multip... 43 0.004
AL049651-2|CAB51954.1| 575|Homo sapiens thrombomodulin protein. 43 0.004
AF495471-1|AAM03232.1| 575|Homo sapiens thrombomodulin protein. 43 0.004
AF442487-1|AAM21557.1| 737|Homo sapiens delta-notch-like EGF re... 43 0.004
AF093118-1|AAC62107.1| 448|Homo sapiens UP50 protein. 43 0.004
BX640729-1|CAE45845.1| 674|Homo sapiens hypothetical protein pr... 43 0.005
AL136322-1|CAI16644.1| 674|Homo sapiens crumbs homolog 1 (Droso... 43 0.005
AF054501-1|AAC39881.1| 161|Homo sapiens latent transforming gro... 43 0.005
X79683-1|CAA56130.1| 1798|Homo sapiens beta2/S laminin chain pro... 42 0.007
AK056571-1|BAB71219.1| 955|Homo sapiens protein ( Homo sapiens ... 42 0.007
AF093119-1|AAC62108.1| 439|Homo sapiens UPH1 protein. 42 0.007
U70312-1|AAC02648.1| 480|Homo sapiens integrin binding protein ... 42 0.009
M17778-1|AAA36799.1| 640|Homo sapiens protein ( Human uromoduli... 42 0.009
M15881-1|AAA36798.1| 640|Homo sapiens protein ( Human uromoduli... 42 0.009
CR457380-1|CAG33661.1| 422|Homo sapiens CRELD1 protein. 42 0.009
BC035975-1|AAH35975.1| 611|Homo sapiens UMOD protein protein. 42 0.009
BC030828-1|AAH30828.1| 480|Homo sapiens EGF-like repeats and di... 42 0.009
AY162970-1|AAO64446.1| 640|Homo sapiens uromodulin precursor pr... 42 0.009
BC047916-1|AAH47916.1| 347|Homo sapiens SCUBE1 protein protein. 42 0.011
BC008720-1|AAH08720.1| 422|Homo sapiens cysteine-rich with EGF-... 42 0.011
AY358363-1|AAQ88729.1| 420|Homo sapiens CRELD1 protein. 42 0.011
AL450324-2|CAI13283.1| 186|Homo sapiens protein ( Human DNA seq... 42 0.011
AF452623-1|AAM75206.1| 420|Homo sapiens cysteine-rich with EGF-... 42 0.011
AF124486-1|AAG45245.1| 443|Homo sapiens fibulin-like extracellu... 42 0.011
X84900-1|CAA59325.1| 1806|Homo sapiens alpha 3B chain of laminin... 41 0.015
M61951-1|AAA59486.1| 1786|Homo sapiens laminin B1 protein. 41 0.015
M61916-1|AAA59482.1| 1786|Homo sapiens laminin B1 protein. 41 0.015
M55370-1|AAA59485.1| 1786|Homo sapiens laminin B1 protein. 41 0.015
DQ138965-1|AAZ66768.1| 203|Homo sapiens truncated brevideltinin... 41 0.015
BC113455-1|AAI13456.1| 1786|Homo sapiens laminin, beta 1 protein. 41 0.015
BC026018-1|AAH26018.2| 1083|Homo sapiens LAMB1 protein protein. 41 0.015
AY327116-1|AAQ72571.1| 3277|Homo sapiens laminin alpha 3 splice ... 41 0.015
AY327115-1|AAQ72570.1| 3333|Homo sapiens laminin alpha 3 splice ... 41 0.015
AL354836-5|CAC22310.1| 3690|Homo sapiens laminin, alpha 5 protein. 41 0.015
AC008273-1|AAF19247.2| 291|Homo sapiens unknown protein. 41 0.015
AB107369-1|BAD13428.1| 3333|Homo sapiens laminin alpha 3b chain ... 41 0.015
X94630-1|CAA64333.1| 835|Homo sapiens seven-span transmembrane ... 41 0.020
X85108-1|CAA59429.1| 1331|Homo sapiens alpha3b subunit of lamini... 41 0.020
X12892-1|CAA31383.1| 650|Homo sapiens protein ( H.sapiens mRNA ... 41 0.020
M14338-1|AAA60181.1| 650|Homo sapiens protein S precursor protein. 41 0.020
BC077719-1|AAH77719.1| 219|Homo sapiens VWCE protein protein. 41 0.020
BC052564-1|AAH52564.1| 219|Homo sapiens VWCE protein protein. 41 0.020
BC042143-1|AAH42143.1| 237|Homo sapiens VWCE protein protein. 41 0.020
AY714129-1|AAU94938.1| 4186|Homo sapiens anchor protein protein. 41 0.020
AF443072-1|AAM12527.1| 3695|Homo sapiens laminin alpha5 chain pr... 41 0.020
AF231023-1|AAF61929.1| 3312|Homo sapiens protocadherin Flamingo ... 41 0.020
AB065966-1|BAC06178.1| 837|Homo sapiens seven transmembrane hel... 41 0.020
AB033063-1|BAA86551.2| 1268|Homo sapiens KIAA1237 protein protein. 41 0.020
Z68155-1|CAA92279.1| 1798|Homo sapiens laminin beta 2 chain prot... 40 0.026
U76764-1|AAB36682.1| 835|Homo sapiens CD97 protein. 40 0.026
S54426-1|AAB25244.1| 109|Homo sapiens fibrillin protein. 40 0.026
AC019195-1|AAY14953.1| 546|Homo sapiens unknown protein. 40 0.026
BC127005-1|AAI27006.1| 823|Homo sapiens egf-like module contain... 40 0.035
BC127004-1|AAI27005.1| 823|Homo sapiens egf-like module contain... 40 0.035
BC090943-1|AAH90943.1| 249|Homo sapiens NOTCH2NL protein protein. 40 0.035
BC065219-1|AAH65219.2| 236|Homo sapiens Notch homolog 2 (Drosop... 40 0.035
BC019835-1|AAH19835.1| 236|Homo sapiens Notch homolog 2 N-termi... 40 0.035
M55210-1|AAA59492.1| 1609|Homo sapiens laminin B2 chain protein. 40 0.046
J03202-1|AAA59488.1| 1609|Homo sapiens LAMB2 protein. 40 0.046
DQ470676-1|ABF06668.1| 321|Homo sapiens CRELD2-alpha protein. 40 0.046
BC002894-1|AAH02894.1| 321|Homo sapiens CRELD2 protein protein. 40 0.046
AY280362-1|AAP35084.1| 2386|Homo sapiens EGF domain-containing p... 40 0.046
AL137311-1|CAB70690.1| 252|Homo sapiens hypothetical protein pr... 40 0.046
AJ968414-1|CAI91316.1| 284|Homo sapiens Cysteine-rich with EGF-... 40 0.046
AB040888-1|BAA95979.2| 2450|Homo sapiens KIAA1455 protein protein. 40 0.046
AB011541-1|BAA32469.2| 2785|Homo sapiens MEGF8 protein. 40 0.046
L34155-1|AAA59483.1| 1713|Homo sapiens epiligrin alpha 3 subunit... 39 0.061
DQ470677-1|ABF06669.1| 325|Homo sapiens CRELD2-gamma protein. 39 0.061
AY327114-1|AAQ72569.1| 1668|Homo sapiens laminin alpha 3 splice ... 39 0.061
X85107-1|CAA59428.1| 1238|Homo sapiens alpha3a subunit of lamini... 39 0.081
BX537434-1|CAD97676.1| 236|Homo sapiens hypothetical protein pr... 39 0.081
BC084572-1|AAH84572.1| 343|Homo sapiens NOTCH2NL protein protein. 39 0.081
BC010154-1|AAH10154.3| 236|Homo sapiens Notch homolog 2 (Drosop... 39 0.081
BC006425-1|AAH06425.1| 204|Homo sapiens EGFL9 protein protein. 39 0.081
BC000230-1|AAH00230.1| 204|Homo sapiens EGFL9 protein protein. 39 0.081
AL592307-2|CAH73994.1| 230|Homo sapiens Notch homolog 2 (Drosop... 39 0.081
AL592307-1|CAH73993.1| 236|Homo sapiens Notch homolog 2 (Drosop... 39 0.081
AK075065-1|BAC11381.1| 269|Homo sapiens protein ( Homo sapiens ... 39 0.081
AF283408-1|AAL38109.1| 1537|Homo sapiens candidate tumor suppres... 39 0.081
AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein... 39 0.081
AC093039-1|AAX88911.1| 425|Homo sapiens unknown protein. 39 0.081
AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA178... 39 0.081
AK222891-1|BAD96611.1| 810|Homo sapiens egf-like module contain... 38 0.11
AF114491-1|AAF21974.1| 823|Homo sapiens EGF-like module EMR2 pr... 38 0.11
AB065931-1|BAC06146.1| 837|Homo sapiens seven transmembrane hel... 38 0.11
S83182-1|AAB46909.1| 560|Homo sapiens hyaluronan-binding protei... 38 0.14
M64283-1|AAA52699.1| 453|Homo sapiens heparan sulfate proteogly... 38 0.14
D49742-1|BAA08576.1| 560|Homo sapiens HGF activator like protei... 38 0.14
BC031412-1|AAH31412.1| 560|Homo sapiens hyaluronan binding prot... 38 0.14
AY534754-1|AAS16352.1| 560|Homo sapiens hyaluronan binding prot... 38 0.14
AL390197-1|CAH71108.1| 560|Homo sapiens hyaluronan binding prot... 38 0.14
AK122706-1|BAC85504.1| 814|Homo sapiens ISOFORM. protein. 38 0.14
AB067494-1|BAB67800.1| 1737|Homo sapiens KIAA1907 protein protein. 38 0.14
L13720-1|AAA58494.1| 678|Homo sapiens growth-arrest-specific pr... 38 0.19
BX072579-3|CAH71174.1| 678|Homo sapiens growth arrest-specific ... 38 0.19
BC132765-1|AAI32766.1| 832|Homo sapiens ADAM metallopeptidase d... 38 0.19
BC132763-1|AAI32764.1| 832|Homo sapiens ADAM metallopeptidase d... 38 0.19
BC084578-1|AAH84578.1| 719|Homo sapiens AGRN protein protein. 38 0.19
BC038984-1|AAH38984.1| 678|Homo sapiens growth arrest-specific ... 38 0.19
AY256843-1|AAO84057.1| 678|Homo sapiens growth arrested-specifi... 38 0.19
AK126533-1|BAC86580.1| 624|Homo sapiens protein ( Homo sapiens ... 38 0.19
AJ005580-1|CAC20565.1| 832|Homo sapiens Adam23 protein protein. 38 0.19
AB009672-1|BAA32351.1| 832|Homo sapiens MDC3 protein. 38 0.19
Z99289-2|CAI42325.1| 1823|Homo sapiens laminin, alpha 4 protein. 37 0.25
X91171-1|CAA62596.1| 1816|Homo sapiens laminin alpha 4 protein. 37 0.25
BC066552-1|AAH66552.1| 1816|Homo sapiens LAMA4 protein protein. 37 0.25
BC038242-1|AAH38242.1| 261|Homo sapiens Similar to RIKEN cDNA 1... 37 0.25
BC026237-1|AAH26237.1| 324|Homo sapiens Unknown (protein for IM... 37 0.25
BC018037-1|AAH18037.1| 379|Homo sapiens WNT inhibitory factor 1... 37 0.25
AY358344-1|AAQ88710.1| 379|Homo sapiens WIF-1 protein. 37 0.25
AL590106-3|CAI12950.1| 1823|Homo sapiens laminin, alpha 4 protein. 37 0.25
AF122922-1|AAD25402.1| 379|Homo sapiens Wnt inhibitory factor-1... 37 0.25
AB210027-1|BAE06109.1| 1852|Homo sapiens LAMA4 variant protein p... 37 0.25
AB209707-1|BAD92944.1| 1720|Homo sapiens low density lipoprotein... 37 0.25
Z99289-8|CAI42333.1| 117|Homo sapiens laminin, alpha 4 protein. 37 0.33
X84700-1|CAA59173.1| 742|Homo sapiens leucocyte antigen CD97 pr... 37 0.33
BC026690-1|AAH26690.1| 742|Homo sapiens CD97 molecule protein. 37 0.33
AY358522-1|AAQ88886.1| 451|Homo sapiens chordin Like protein. 37 0.33
AY279093-1|AAQ19182.1| 142|Homo sapiens chordin-related protein... 37 0.33
AY279091-1|AAQ19180.1| 308|Homo sapiens chordin-related protein... 37 0.33
AY279090-1|AAQ19179.1| 429|Homo sapiens chordin-related protein... 37 0.33
AY163868-1|AAO31809.1| 451|Homo sapiens BNF1 protein. 37 0.33
AF187072-1|AAF08273.1| 515|Homo sapiens N-acetylglucosamine-1-p... 37 0.33
AF028816-1|AAC95123.1| 1761|Homo sapiens laminin beta-4 chain pr... 37 0.33
S76436-1|AAB21121.2| 507|Homo sapiens heparan sulfate proteogly... 36 0.43
BC126987-1|AAI26988.1| 305|Homo sapiens FLJ37440 protein protein. 36 0.43
BC109204-1|AAI09205.1| 351|Homo sapiens HSPG2 protein protein. 36 0.43
BC033228-1|AAH33228.1| 439|Homo sapiens MEGF8 protein protein. 36 0.43
AL137007-1|CAC10575.2| 199|Homo sapiens novel EGF-like domain c... 36 0.43
AC005327-1|AAC27673.1| 287|Homo sapiens CD97_HUMAN, partial CDS... 36 0.43
AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-speci... 36 0.43
AB037723-1|BAA92540.3| 2016|Homo sapiens KIAA1302 protein protein. 36 0.43
X63755-1|CAA45283.1| 169|Homo sapiens high-sulpher keratin prot... 36 0.57
BC060770-1|AAH60770.2| 757|Homo sapiens SUSD1 protein protein. 36 0.57
AY358746-1|AAQ89106.1| 747|Homo sapiens GRGP2438 protein. 36 0.57
AL158824-3|CAI12348.2| 705|Homo sapiens sushi domain containing... 36 0.57
AL158824-2|CAI12347.2| 747|Homo sapiens sushi domain containing... 36 0.57
AL138756-2|CAI95300.2| 705|Homo sapiens sushi domain containing... 36 0.57
AL138756-1|CAI95299.2| 747|Homo sapiens sushi domain containing... 36 0.57
AK075536-1|BAC11679.1| 529|Homo sapiens protein ( Homo sapiens ... 36 0.57
AF005258-1|AAC51867.1| 1486|Homo sapiens laminin alpha 3b chain ... 36 0.57
AC013451-1|AAF87081.1| 969|Homo sapiens LTBP-2 protein. 36 0.57
AB032953-1|BAA86441.2| 2144|Homo sapiens KIAA1127 protein protein. 36 0.57
Z99289-7|CAI42332.1| 177|Homo sapiens laminin, alpha 4 protein. 36 0.75
>L32137-1|AAA57253.1| 757|Homo sapiens matrix protein protein.
Length = 757
Score = 582 bits (1436), Expect = e-165
Identities = 291/654 (44%), Positives = 361/654 (55%), Gaps = 29/654 (4%)
Query: 153 CEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX--XXXXXXSQGWRGT 210
C CP+G+ NG C D++EC+ PC V C N QG
Sbjct: 111 CGPCPAGFTGNGSHCTDVNECNA-HPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLA 169
Query: 211 GNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTT 270
+ ++ C D++EC G+ NC +C+NT +GS+ C PC + +
Sbjct: 170 FAKANKQVCTDINECETGQHNCVPNSVCINT-----------RGSFQCGPCQPGFVGDQA 218
Query: 271 RPCF-DPDSLVKRCDPSYCRRFNAVCGF----GQKCVCNTGWTGNGTVCGLDRDLDGHPD 325
C PS C +A C + CVC GW GNG +CG D DLDG PD
Sbjct: 219 SGCQRGAQRFCPDGSPSECHE-HADCVLERDGSRSCVCRVGWAGNGILCGRDTDLDGFPD 277
Query: 326 EQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDNCPLTPNPDQL 385
E+L C EP+C+KDNC V NSGQE +PN DNCPL NPDQ
Sbjct: 278 EKLRCPEPQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGVPNEKDNCPLVRNPDQR 337
Query: 386 DDDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXXXXXXXXIPNQVDNCPRKYNPQ 445
+ DE D+ G+ACDNC N Q+ I NQ DNCPR N
Sbjct: 338 NTDE---DKWGDACDNCRSQKNDDQKDTDQDGRGDACDDDIDGDRIRNQADNCPRVPNSD 394
Query: 446 QDDMDSDGVGDVCDNCPRVRNTNQEDTDKDNVGDACXXXXXXXXXXXXXXXXNCPLIPNS 505
Q D D DG+GD CDNCP+ N +Q D D D VGDAC NCP +PNS
Sbjct: 395 QKDSDGDGIGDACDNCPQKSNPDQADVDHDFVGDACDSDQDQDGDGHQDSRDNCPTVPNS 454
Query: 506 XXXXXXXXXXXXXXXXXXXXXXXXXXXXNCQIVPNRDQKDSDNDGIGDACDNDIDGDRVI 565
NC++VPN Q+D+D DG+GD C +D D D+V+
Sbjct: 455 AQEDSDHDGQGDACDDDDDNDGVPDSRDNCRLVPNPGQEDADRDGVGDVCQDDFDADKVV 514
Query: 566 NELDNCPTIRRYFERTSGTLMRCRQFTTVRLDPEGESQQEPNWRVTDNGAEILQTLHSDP 625
+++D CP E TL R F TV LDPEG++Q +PNW V + G EI+QT++SDP
Sbjct: 515 DKIDVCP------ENAEVTLTDFRAFQTVVLDPEGDAQIDPNWVVLNQGREIVQTMNSDP 568
Query: 626 GLAVGFDSFGGVDYEGTIFVNTKIDDDYVGFIFGYQSNKRFYVVMWKKDKQTYWQKTPFR 685
GLAVG+ +F GVD+EGT VNT DDDY GFIFGYQ + FYVVMWK+ +QTYWQ PFR
Sbjct: 569 GLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQMEQTYWQANPFR 628
Query: 686 AVAENGIQLKLVNSKTGPGKILRNALWNTNSTPDQVTLLWKDPRNVGWREQTAYRWKLLH 745
AVAE GIQLK V S TGPG+ LRNALW+T T QV LLWKDPRNVGW+++ +YRW L H
Sbjct: 629 AVAEPGIQLKAVKSSTGPGEQLRNALWHTGDTESQVRLLWKDPRNVGWKDKKSYRWFLQH 688
Query: 746 RPKIGLIRLKMYENNRLVADSGNTYDFTLKGGRLGVFCFSQEMIIWSNLLYKCN 799
RP++G IR++ YE LVADS D T++GGRLGVFCFSQE IIW+NL Y+CN
Sbjct: 689 RPQVGYIRVRFYEGPELVADSNVVLDTTMRGGRLGVFCFSQENIIWANLRYRCN 742
Score = 140 bits (338), Expect = 2e-32
Identities = 131/439 (29%), Positives = 167/439 (38%), Gaps = 70/439 (15%)
Query: 90 ISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKPCGRERRCMPKST 147
+ C CF GV+C +T+ G +CG CP G+ G+G C V C+A PC RC+ +T
Sbjct: 89 LHCAPGFCFPGVACIQTESGGRCGPCPAGFTGNGSHCTDVNECNAH-PCFPRVRCI--NT 145
Query: 148 SPYYECEGCPSGY-------------QWNGYTCVDMDECDL-IRPCDDLVSCRNEEXXXX 193
SP + CE CP GY + N C D++EC+ C C N
Sbjct: 146 SPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQ 205
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGR-ANCPRGRLCVNTPQYPSNPVSSL 252
Q +G +R + C DG + C CV + V +
Sbjct: 206 CGPCQPGFVGDQ---ASGCQRGAQRF-----CPDGSPSECHEHADCVLERDGSRSCVCRV 257
Query: 253 QGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC--GFGQKCVCNTGWTGN 310
+ + CG +T F + L RC CR+ N V GQ+ V G
Sbjct: 258 GWAGNGILCGR----DTDLDGFPDEKL--RCPEPQCRKDNCVTVPNSGQEDVDR---DGI 308
Query: 311 GTVCGLDRDLDGHPDEQLPC---NEPRCKK----------DNCPDVSNSGQEXXXXXXXX 357
G C D D DG P+E+ C P + DNC N Q+
Sbjct: 309 GDACDPDADGDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQKDTDQDGRG 368
Query: 358 XXXXXXXXXXXIPNFPDNCPLTPNPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXX 417
I N DNCP PN DQ D D D G+ACDNCP+ NP Q
Sbjct: 369 DACDDDIDGDRIRNQADNCPRVPNSDQKDSD---GDGIGDACDNCPQKSNPDQADVDHDF 425
Query: 418 XXXXXXXXXXXXXIPNQ--VDNCPRKYNPQQDDMDSDGVGDVC-------------DNCP 462
+Q DNCP N Q+D D DG GD C DNC
Sbjct: 426 VGDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPDSRDNCR 485
Query: 463 RVRNTNQEDTDKDNVGDAC 481
V N QED D+D VGD C
Sbjct: 486 LVPNPGQEDADRDGVGDVC 504
Score = 108 bits (260), Expect = 7e-23
Identities = 122/447 (27%), Positives = 155/447 (34%), Gaps = 68/447 (15%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYG 109
C+ CF G Q GR CG CP+GF GNG C ++ C A+ CF V C T G
Sbjct: 91 CAPGFCFPGVACIQTESGGR--CGPCPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPG 148
Query: 110 PKCGSCPTGYVGDGRQ---------CQHVCDAQKPCGR-ERRCMPKS----TSPYYECEG 155
+C +CP GY G Q + VC C + C+P S T ++C
Sbjct: 149 FRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGP 208
Query: 156 CPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERR 215
C G+ + + P C GW G G
Sbjct: 209 CQPGFVGDQASGCQRG-AQRFCPDGSPSECHEHADCVLERDGSRSCVCRVGWAGNGILCG 267
Query: 216 REHCVDVDECADGRANCP----RGRLCVNTPQYPSNPVSSLQGSYICVP-CGGHYYVNTT 270
R+ D+D D + CP R CV P V C P G N
Sbjct: 268 RD--TDLDGFPDEKLRCPEPQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGVPNEK 325
Query: 271 RPC---FDPDSLVKRCDP--SYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPD 325
C +PD D C + QK +T G G C D D+DG
Sbjct: 326 DNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQK---DTDQDGRGDAC--DDDIDG--- 377
Query: 326 EQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDNCPLTPNPDQL 385
+ R + DNCP V NS Q+ I + DNCP NPDQ
Sbjct: 378 -----DRIRNQADNCPRVPNSDQK-------------DSDGDGIGDACDNCPQKSNPDQA 419
Query: 386 D------------DDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXXXXXXXXIPN 433
D D + D ++ DNCP N QE +P+
Sbjct: 420 DVDHDFVGDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPD 479
Query: 434 QVDNCPRKYNPQQDDMDSDGVGDVCDN 460
DNC NP Q+D D DGVGDVC +
Sbjct: 480 SRDNCRLVPNPGQEDADRDGVGDVCQD 506
Score = 62.5 bits (145), Expect = 6e-09
Identities = 51/171 (29%), Positives = 68/171 (39%), Gaps = 27/171 (15%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCR--TACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
G C+ T+ G RC CP T +G C C+A+PCF RV C + G ++C CP
Sbjct: 99 GVACIQTESGGRCGPCPAGFTGNGSHCTDVNECNAHPCF-PRVRCINTSPG-FRCEACPP 156
Query: 79 GFHG-------------NGVECYRIS-CRA--NTCFQGVSCEETQYGPKCGSCPTGYVGD 122
G+ G N C I+ C + C C T+ +CG C G+VGD
Sbjct: 157 GYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGD 216
Query: 123 -GRQCQHVCDAQKPCGRERRCMPKSTSPYYECEG-----CPSGYQWNGYTC 167
CQ P G C + E +G C G+ NG C
Sbjct: 217 QASGCQRGAQRFCPDGSPSEC-HEHADCVLERDGSRSCVCRVGWAGNGILC 266
Score = 45.6 bits (103), Expect = 7e-04
Identities = 44/163 (26%), Positives = 64/163 (39%), Gaps = 27/163 (16%)
Query: 23 RCVDTDQGFRCERCP---GSQTSDG------QTCRTACS-ANPCFGGRVPCQDLPD---- 68
RC++T GFRCE CP T G + + C+ N C G+ C +P+
Sbjct: 141 RCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNC--VPNSVCI 198
Query: 69 ---GRYQCGKCPSGFHGNGVE-CYRISCR------ANTCFQGVSCEETQYGPKCGSCPTG 118
G +QCG C GF G+ C R + R + C + C + G + C G
Sbjct: 199 NTRGSFQCGPCQPGFVGDQASGCQRGAQRFCPDGSPSECHEHADCVLERDGSRSCVCRVG 258
Query: 119 YVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ 161
+ G+G C D + RC P+ C P+ Q
Sbjct: 259 WAGNGILCGRDTDLDGFPDEKLRC-PEPQCRKDNCVTVPNSGQ 300
>AB086984-1|BAC53888.1| 757|Homo sapiens cartilage oligomeric
matrix protein protein.
Length = 757
Score = 582 bits (1436), Expect = e-165
Identities = 291/654 (44%), Positives = 361/654 (55%), Gaps = 29/654 (4%)
Query: 153 CEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX--XXXXXXSQGWRGT 210
C CP+G+ NG C D++EC+ PC V C N QG
Sbjct: 111 CGPCPAGFTGNGSHCTDVNECNA-HPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLA 169
Query: 211 GNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTT 270
+ ++ C D++EC G+ NC +C+NT +GS+ C PC + +
Sbjct: 170 FAKANKQVCTDINECETGQHNCVPNSVCINT-----------RGSFQCGPCQPGFVGDQA 218
Query: 271 RPCF-DPDSLVKRCDPSYCRRFNAVCGF----GQKCVCNTGWTGNGTVCGLDRDLDGHPD 325
C PS C +A C + CVC GW GNG +CG D DLDG PD
Sbjct: 219 SGCQRGAQRFCPDGSPSECHE-HADCVLERDGSRSCVCRVGWAGNGILCGRDTDLDGFPD 277
Query: 326 EQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDNCPLTPNPDQL 385
E+L C EP+C+KDNC V NSGQE +PN DNCPL NPDQ
Sbjct: 278 EKLRCPEPQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGVPNEKDNCPLVRNPDQR 337
Query: 386 DDDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXXXXXXXXIPNQVDNCPRKYNPQ 445
+ DE D+ G+ACDNC N Q+ I NQ DNCPR N
Sbjct: 338 NTDE---DKWGDACDNCRSQKNDDQKDTDQDGRGDACDDDIDGDRIRNQADNCPRVPNSD 394
Query: 446 QDDMDSDGVGDVCDNCPRVRNTNQEDTDKDNVGDACXXXXXXXXXXXXXXXXNCPLIPNS 505
Q D D DG+GD CDNCP+ N +Q D D D VGDAC NCP +PNS
Sbjct: 395 QKDSDGDGIGDACDNCPQKSNPDQADVDHDFVGDACDSDQDQDGDGHQDSRDNCPTVPNS 454
Query: 506 XXXXXXXXXXXXXXXXXXXXXXXXXXXXNCQIVPNRDQKDSDNDGIGDACDNDIDGDRVI 565
NC++VPN Q+D+D DG+GD C +D D D+V+
Sbjct: 455 AQEDSDHDGQGDACDDDDDNDGVPDSRDNCRLVPNPGQEDADRDGVGDVCQDDFDADKVV 514
Query: 566 NELDNCPTIRRYFERTSGTLMRCRQFTTVRLDPEGESQQEPNWRVTDNGAEILQTLHSDP 625
+++D CP E TL R F TV LDPEG++Q +PNW V + G EI+QT++SDP
Sbjct: 515 DKIDVCP------ENAEVTLTDFRAFQTVVLDPEGDAQIDPNWVVLNQGREIVQTMNSDP 568
Query: 626 GLAVGFDSFGGVDYEGTIFVNTKIDDDYVGFIFGYQSNKRFYVVMWKKDKQTYWQKTPFR 685
GLAVG+ +F GVD+EGT VNT DDDY GFIFGYQ + FYVVMWK+ +QTYWQ PFR
Sbjct: 569 GLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQMEQTYWQANPFR 628
Query: 686 AVAENGIQLKLVNSKTGPGKILRNALWNTNSTPDQVTLLWKDPRNVGWREQTAYRWKLLH 745
AVAE GIQLK V S TGPG+ LRNALW+T T QV LLWKDPRNVGW+++ +YRW L H
Sbjct: 629 AVAEPGIQLKAVKSSTGPGEQLRNALWHTGDTESQVRLLWKDPRNVGWKDKKSYRWFLQH 688
Query: 746 RPKIGLIRLKMYENNRLVADSGNTYDFTLKGGRLGVFCFSQEMIIWSNLLYKCN 799
RP++G IR++ YE LVADS D T++GGRLGVFCFSQE IIW+NL Y+CN
Sbjct: 689 RPQVGYIRVRFYEGPELVADSNVVLDTTMRGGRLGVFCFSQENIIWANLRYRCN 742
Score = 140 bits (338), Expect = 2e-32
Identities = 131/439 (29%), Positives = 167/439 (38%), Gaps = 70/439 (15%)
Query: 90 ISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKPCGRERRCMPKST 147
+ C CF GV+C +T+ G +CG CP G+ G+G C V C+A PC RC+ +T
Sbjct: 89 LHCAPGFCFPGVACIQTESGGRCGPCPAGFTGNGSHCTDVNECNAH-PCFPRVRCI--NT 145
Query: 148 SPYYECEGCPSGY-------------QWNGYTCVDMDECDL-IRPCDDLVSCRNEEXXXX 193
SP + CE CP GY + N C D++EC+ C C N
Sbjct: 146 SPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQ 205
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGR-ANCPRGRLCVNTPQYPSNPVSSL 252
Q +G +R + C DG + C CV + V +
Sbjct: 206 CGPCQPGFVGDQ---ASGCQRGAQRF-----CPDGSPSECHEHADCVLERDGSRSCVCRV 257
Query: 253 QGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC--GFGQKCVCNTGWTGN 310
+ + CG +T F + L RC CR+ N V GQ+ V G
Sbjct: 258 GWAGNGILCGR----DTDLDGFPDEKL--RCPEPQCRKDNCVTVPNSGQEDVDR---DGI 308
Query: 311 GTVCGLDRDLDGHPDEQLPC---NEPRCKK----------DNCPDVSNSGQEXXXXXXXX 357
G C D D DG P+E+ C P + DNC N Q+
Sbjct: 309 GDACDPDADGDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQKDTDQDGRG 368
Query: 358 XXXXXXXXXXXIPNFPDNCPLTPNPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXX 417
I N DNCP PN DQ D D D G+ACDNCP+ NP Q
Sbjct: 369 DACDDDIDGDRIRNQADNCPRVPNSDQKDSD---GDGIGDACDNCPQKSNPDQADVDHDF 425
Query: 418 XXXXXXXXXXXXXIPNQ--VDNCPRKYNPQQDDMDSDGVGDVC-------------DNCP 462
+Q DNCP N Q+D D DG GD C DNC
Sbjct: 426 VGDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPDSRDNCR 485
Query: 463 RVRNTNQEDTDKDNVGDAC 481
V N QED D+D VGD C
Sbjct: 486 LVPNPGQEDADRDGVGDVC 504
Score = 108 bits (260), Expect = 7e-23
Identities = 122/447 (27%), Positives = 155/447 (34%), Gaps = 68/447 (15%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYG 109
C+ CF G Q GR CG CP+GF GNG C ++ C A+ CF V C T G
Sbjct: 91 CAPGFCFPGVACIQTESGGR--CGPCPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPG 148
Query: 110 PKCGSCPTGYVGDGRQ---------CQHVCDAQKPCGR-ERRCMPKS----TSPYYECEG 155
+C +CP GY G Q + VC C + C+P S T ++C
Sbjct: 149 FRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGP 208
Query: 156 CPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERR 215
C G+ + + P C GW G G
Sbjct: 209 CQPGFVGDQASGCQRG-AQRFCPDGSPSECHEHADCVLERDGSRSCVCRVGWAGNGILCG 267
Query: 216 REHCVDVDECADGRANCP----RGRLCVNTPQYPSNPVSSLQGSYICVP-CGGHYYVNTT 270
R+ D+D D + CP R CV P V C P G N
Sbjct: 268 RD--TDLDGFPDEKLRCPEPQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGVPNEK 325
Query: 271 RPC---FDPDSLVKRCDP--SYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPD 325
C +PD D C + QK +T G G C D D+DG
Sbjct: 326 DNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQK---DTDQDGRGDAC--DDDIDG--- 377
Query: 326 EQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDNCPLTPNPDQL 385
+ R + DNCP V NS Q+ I + DNCP NPDQ
Sbjct: 378 -----DRIRNQADNCPRVPNSDQK-------------DSDGDGIGDACDNCPQKSNPDQA 419
Query: 386 D------------DDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXXXXXXXXIPN 433
D D + D ++ DNCP N QE +P+
Sbjct: 420 DVDHDFVGDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPD 479
Query: 434 QVDNCPRKYNPQQDDMDSDGVGDVCDN 460
DNC NP Q+D D DGVGDVC +
Sbjct: 480 SRDNCRLVPNPGQEDADRDGVGDVCQD 506
Score = 62.5 bits (145), Expect = 6e-09
Identities = 51/171 (29%), Positives = 68/171 (39%), Gaps = 27/171 (15%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCR--TACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
G C+ T+ G RC CP T +G C C+A+PCF RV C + G ++C CP
Sbjct: 99 GVACIQTESGGRCGPCPAGFTGNGSHCTDVNECNAHPCF-PRVRCINTSPG-FRCEACPP 156
Query: 79 GFHG-------------NGVECYRIS-CRA--NTCFQGVSCEETQYGPKCGSCPTGYVGD 122
G+ G N C I+ C + C C T+ +CG C G+VGD
Sbjct: 157 GYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGD 216
Query: 123 -GRQCQHVCDAQKPCGRERRCMPKSTSPYYECEG-----CPSGYQWNGYTC 167
CQ P G C + E +G C G+ NG C
Sbjct: 217 QASGCQRGAQRFCPDGSPSEC-HEHADCVLERDGSRSCVCRVGWAGNGILC 266
Score = 45.6 bits (103), Expect = 7e-04
Identities = 44/163 (26%), Positives = 64/163 (39%), Gaps = 27/163 (16%)
Query: 23 RCVDTDQGFRCERCP---GSQTSDG------QTCRTACS-ANPCFGGRVPCQDLPD---- 68
RC++T GFRCE CP T G + + C+ N C G+ C +P+
Sbjct: 141 RCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNC--VPNSVCI 198
Query: 69 ---GRYQCGKCPSGFHGNGVE-CYRISCR------ANTCFQGVSCEETQYGPKCGSCPTG 118
G +QCG C GF G+ C R + R + C + C + G + C G
Sbjct: 199 NTRGSFQCGPCQPGFVGDQASGCQRGAQRFCPDGSPSECHEHADCVLERDGSRSCVCRVG 258
Query: 119 YVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ 161
+ G+G C D + RC P+ C P+ Q
Sbjct: 259 WAGNGILCGRDTDLDGFPDEKLRC-PEPQCRKDNCVTVPNSGQ 300
>L38969-1|AAC41762.1| 956|Homo sapiens thrombospondin 3 protein.
Length = 956
Score = 580 bits (1433), Expect = e-165
Identities = 304/679 (44%), Positives = 372/679 (54%), Gaps = 37/679 (5%)
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXX 194
PC R CM P Y C CP G Q NG C D++EC PC SC N
Sbjct: 282 PCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCINTMPGFHC 341
Query: 195 XXXXXXXXXSQGWRGTGNERRR---EHCVDVDECADGR-ANCPRGRLCVNTPQYPSNPVS 250
+Q G G + R + C D+DEC DG C +C NT
Sbjct: 342 EACPRGYKGTQV-SGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTV-------- 392
Query: 251 SLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQK----CVCNTG 306
GS+ C PC + N ++ C P S C +A C F + C CN G
Sbjct: 393 ---GSFKCGPCRLGFLGNQSQGCL-PARTCHSPAHSPCH-IHAHCLFERNGAVSCQCNVG 447
Query: 307 WTGNGTVCGLDRDLDGHPDEQLPC--NEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXX 364
W GNG VCG D D+DG+PD+ LPC N CK+DNC NSGQE
Sbjct: 448 WAGNGNVCGTDTDIDGYPDQALPCMDNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDA 507
Query: 365 XXXXIPNFPDNCPLTPNPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXX 424
I N DNC L PN DQ + D +D G+ACDNCP N Q+
Sbjct: 508 DGDGIKNVEDNCRLFPNKDQQNSD---TDSFGDACDNCPNVPNNDQKDTDGNGEGDACDN 564
Query: 425 XXXXXXIPNQVDNCPRKYNPQQDDMDSDGVGDVCDNCPRVRNTNQEDTDKDNVGDACXXX 484
IPN +DNCP+ NP Q D D DGVGD CD+CP + N Q D D D VGD C
Sbjct: 565 DVDGDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTN 624
Query: 485 XXXXXXXXXXXXXNCPLIPNSXXXXXXXXXXXXXXXXXXXXXXXXXXX----XNCQIVPN 540
NCP +PNS NC++VPN
Sbjct: 625 EDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPN 684
Query: 541 RDQKDSDNDGIGDACDNDIDGDRVINELDNCPTIRRYFERTSGTLMRCRQFTTVRLDPEG 600
+QKDSD +G+GD C++D D D V++ LD CP E TL R + TV LDPEG
Sbjct: 685 PNQKDSDGNGVGDVCEDDFDNDAVVDPLDVCP------ESAEVTLTDFRAYQTVVLDPEG 738
Query: 601 ESQQEPNWRVTDNGAEILQTLHSDPGLAVGFDSFGGVDYEGTIFVNTKIDDDYVGFIFGY 660
++Q +PNW V + G EI+QT++SDPGLAVG+ +F GVD+EGT VNT DDDY GF+F Y
Sbjct: 739 DAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSY 798
Query: 661 QSNKRFYVVMWKKDKQTYWQKTPFRAVAENGIQLKLVNSKTGPGKILRNALWNTNSTPDQ 720
Q + RFYVVMWK+ +QTYWQ TPFRAVA+ G+QLK V S +GPG+ LRNALW+T TPDQ
Sbjct: 799 QDSGRFYVVMWKQTEQTYWQATPFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQ 858
Query: 721 VTLLWKDPRNVGWREQTAYRWKLLHRPKIGLIRLKMYENNRLVADSGNTYDFTLKGGRLG 780
V LLW DPRNVGWR++T+YRW+LLHRP++G IR+K+YE +LVADSG D +++GGRLG
Sbjct: 859 VRLLWTDPRNVGWRDKTSYRWQLLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLG 918
Query: 781 VFCFSQEMIIWSNLLYKCN 799
VFCFSQE IIWSNL Y+CN
Sbjct: 919 VFCFSQENIIWSNLQYRCN 937
Score = 97.9 bits (233), Expect = 1e-19
Identities = 125/461 (27%), Positives = 162/461 (35%), Gaps = 82/461 (17%)
Query: 48 RTACSANPCFGGRVPCQDLPD-GRYQCGKCPSGFHGNGVECYRIS--CRANTCFQGVSCE 104
R+ CS NPCF G V C ++ + Y+CG CP G GNG C I+ A+ CF G SC
Sbjct: 275 RSHCSPNPCFRG-VDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCI 333
Query: 105 ETQYGPKCGSCPTGYVGD---------GRQCQHVCDAQKPC--GRERRCMPKS----TSP 149
T G C +CP GY G R + VC+ C G C P S T
Sbjct: 334 NTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVG 393
Query: 150 YYECEGCPSGYQWN-GYTCVDMDEC--DLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQG 206
++C C G+ N C+ C PC C E + G
Sbjct: 394 SFKCGPCRLGFLGNQSQGCLPARTCHSPAHSPCHIHAHCLFER------NGAVSCQCNVG 447
Query: 207 WRGTGNERRREHCVD--VDE---CADGRANCPRGRLCVNTPQYPSNPV-SSLQGSYICVP 260
W G GN + +D D+ C D +C + C+ TP + G
Sbjct: 448 WAGNGNVCGTDTDIDGYPDQALPCMDNNKHCKQDN-CLLTPNSGQEDADNDGVGDQCDDD 506
Query: 261 CGGHYYVNTTRPC-FDPDSLVKRCDP----SYCRRFNAVCGFGQKCVCNTGWTGNGTVCG 315
G N C P+ + D C V QK +T G G C
Sbjct: 507 ADGDGIKNVEDNCRLFPNKDQQNSDTDSFGDACDNCPNVPNNDQK---DTDGNGEGDACD 563
Query: 316 LDRDLDGHPDEQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDN 375
D D DG P+ DNCP V N Q + + D+
Sbjct: 564 NDVDGDGIPN----------GLDNCPKVPNPLQ-------------TDRDEDGVGDACDS 600
Query: 376 CPLTPNPDQLDDD------------ENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXX 423
CP NP Q D D ++ D + DNCP+ N Q
Sbjct: 601 CPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECD 660
Query: 424 XXXXXXXIPNQV----DNCPRKYNPQQDDMDSDGVGDVCDN 460
IP+ V DNC NP Q D D +GVGDVC++
Sbjct: 661 GDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCED 701
Score = 64.9 bits (151), Expect = 1e-09
Identities = 101/406 (24%), Positives = 142/406 (34%), Gaps = 54/406 (13%)
Query: 30 GFRCERCPGSQTSDGQTCR--TACS-ANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN--- 83
G+RC CP +G C C+ A+PCF G +P + C CP G+ G
Sbjct: 297 GYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCINTMPG--FHCEACPRGYKGTQVS 354
Query: 84 --GVECYRIS---CR-ANTCFQGVS--------CEETQYGPKCGSCPTGYVGDGRQ-C-- 126
G++ R S C + C G + C T KCG C G++G+ Q C
Sbjct: 355 GVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLP 414
Query: 127 QHVC--DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC---VDMDEC-DLIRPC- 179
C A PC C+ + C+ C G+ NG C D+D D PC
Sbjct: 415 ARTCHSPAHSPCHIHAHCLFERNGA-VSCQ-CNVGWAGNGNVCGTDTDIDGYPDQALPCM 472
Query: 180 DDLVSCRNEEXXXXXXXXXXXXXX-------SQGWRGTGNERRREHC-VDVDECADGRAN 231
D+ C+ + G G + ++C + ++
Sbjct: 473 DNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSDT 532
Query: 232 CPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRF 291
G C N P P+N G+ C V+ D+ K +P R
Sbjct: 533 DSFGDACDNCPNVPNNDQKDTDGNGEGDACDND--VDGDGIPNGLDNCPKVPNPLQTDRD 590
Query: 292 NAVCGFGQKCVCNTGWTGNGTVCGLDRDLDG---HPDEQLPCNEPRCKKDNCPDVSNSGQ 348
G G C + N T D DL G +E + + KDNCP + NS Q
Sbjct: 591 ED--GVGDAC-DSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQ 647
Query: 349 EXXXXXXXXXXXXXXXXXXXIPNF----PDNCPLTPNPDQLDDDEN 390
IP++ PDNC L PNP+Q D D N
Sbjct: 648 LDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGN 693
>AL713999-15|CAI95084.1| 956|Homo sapiens thrombospondin 3 protein.
Length = 956
Score = 580 bits (1433), Expect = e-165
Identities = 304/679 (44%), Positives = 372/679 (54%), Gaps = 37/679 (5%)
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXX 194
PC R CM P Y C CP G Q NG C D++EC PC SC N
Sbjct: 282 PCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCINTMPGFHC 341
Query: 195 XXXXXXXXXSQGWRGTGNERRR---EHCVDVDECADGR-ANCPRGRLCVNTPQYPSNPVS 250
+Q G G + R + C D+DEC DG C +C NT
Sbjct: 342 EACPRGYKGTQV-SGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTV-------- 392
Query: 251 SLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQK----CVCNTG 306
GS+ C PC + N ++ C P S C +A C F + C CN G
Sbjct: 393 ---GSFKCGPCRLGFLGNQSQGCL-PARTCHSPAHSPCH-IHAHCLFERNGAVSCQCNVG 447
Query: 307 WTGNGTVCGLDRDLDGHPDEQLPC--NEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXX 364
W GNG VCG D D+DG+PD+ LPC N CK+DNC NSGQE
Sbjct: 448 WAGNGNVCGTDTDIDGYPDQALPCMDNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDA 507
Query: 365 XXXXIPNFPDNCPLTPNPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXX 424
I N DNC L PN DQ + D +D G+ACDNCP N Q+
Sbjct: 508 DGDGIKNVEDNCRLFPNKDQQNSD---TDSFGDACDNCPNVPNNDQKDTDGNGEGDACDN 564
Query: 425 XXXXXXIPNQVDNCPRKYNPQQDDMDSDGVGDVCDNCPRVRNTNQEDTDKDNVGDACXXX 484
IPN +DNCP+ NP Q D D DGVGD CD+CP + N Q D D D VGD C
Sbjct: 565 DVDGDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTN 624
Query: 485 XXXXXXXXXXXXXNCPLIPNSXXXXXXXXXXXXXXXXXXXXXXXXXXX----XNCQIVPN 540
NCP +PNS NC++VPN
Sbjct: 625 EDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPN 684
Query: 541 RDQKDSDNDGIGDACDNDIDGDRVINELDNCPTIRRYFERTSGTLMRCRQFTTVRLDPEG 600
+QKDSD +G+GD C++D D D V++ LD CP E TL R + TV LDPEG
Sbjct: 685 PNQKDSDGNGVGDVCEDDFDNDAVVDPLDVCP------ESAEVTLTDFRAYQTVVLDPEG 738
Query: 601 ESQQEPNWRVTDNGAEILQTLHSDPGLAVGFDSFGGVDYEGTIFVNTKIDDDYVGFIFGY 660
++Q +PNW V + G EI+QT++SDPGLAVG+ +F GVD+EGT VNT DDDY GF+F Y
Sbjct: 739 DAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSY 798
Query: 661 QSNKRFYVVMWKKDKQTYWQKTPFRAVAENGIQLKLVNSKTGPGKILRNALWNTNSTPDQ 720
Q + RFYVVMWK+ +QTYWQ TPFRAVA+ G+QLK V S +GPG+ LRNALW+T TPDQ
Sbjct: 799 QDSGRFYVVMWKQTEQTYWQATPFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQ 858
Query: 721 VTLLWKDPRNVGWREQTAYRWKLLHRPKIGLIRLKMYENNRLVADSGNTYDFTLKGGRLG 780
V LLW DPRNVGWR++T+YRW+LLHRP++G IR+K+YE +LVADSG D +++GGRLG
Sbjct: 859 VRLLWTDPRNVGWRDKTSYRWQLLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLG 918
Query: 781 VFCFSQEMIIWSNLLYKCN 799
VFCFSQE IIWSNL Y+CN
Sbjct: 919 VFCFSQENIIWSNLQYRCN 937
Score = 97.9 bits (233), Expect = 1e-19
Identities = 125/461 (27%), Positives = 162/461 (35%), Gaps = 82/461 (17%)
Query: 48 RTACSANPCFGGRVPCQDLPD-GRYQCGKCPSGFHGNGVECYRIS--CRANTCFQGVSCE 104
R+ CS NPCF G V C ++ + Y+CG CP G GNG C I+ A+ CF G SC
Sbjct: 275 RSHCSPNPCFRG-VDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCI 333
Query: 105 ETQYGPKCGSCPTGYVGD---------GRQCQHVCDAQKPC--GRERRCMPKS----TSP 149
T G C +CP GY G R + VC+ C G C P S T
Sbjct: 334 NTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVG 393
Query: 150 YYECEGCPSGYQWN-GYTCVDMDEC--DLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQG 206
++C C G+ N C+ C PC C E + G
Sbjct: 394 SFKCGPCRLGFLGNQSQGCLPARTCHSPAHSPCHIHAHCLFER------NGAVSCQCNVG 447
Query: 207 WRGTGNERRREHCVD--VDE---CADGRANCPRGRLCVNTPQYPSNPV-SSLQGSYICVP 260
W G GN + +D D+ C D +C + C+ TP + G
Sbjct: 448 WAGNGNVCGTDTDIDGYPDQALPCMDNNKHCKQDN-CLLTPNSGQEDADNDGVGDQCDDD 506
Query: 261 CGGHYYVNTTRPC-FDPDSLVKRCDP----SYCRRFNAVCGFGQKCVCNTGWTGNGTVCG 315
G N C P+ + D C V QK +T G G C
Sbjct: 507 ADGDGIKNVEDNCRLFPNKDQQNSDTDSFGDACDNCPNVPNNDQK---DTDGNGEGDACD 563
Query: 316 LDRDLDGHPDEQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDN 375
D D DG P+ DNCP V N Q + + D+
Sbjct: 564 NDVDGDGIPN----------GLDNCPKVPNPLQ-------------TDRDEDGVGDACDS 600
Query: 376 CPLTPNPDQLDDD------------ENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXX 423
CP NP Q D D ++ D + DNCP+ N Q
Sbjct: 601 CPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECD 660
Query: 424 XXXXXXXIPNQV----DNCPRKYNPQQDDMDSDGVGDVCDN 460
IP+ V DNC NP Q D D +GVGDVC++
Sbjct: 661 GDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCED 701
Score = 64.9 bits (151), Expect = 1e-09
Identities = 101/406 (24%), Positives = 142/406 (34%), Gaps = 54/406 (13%)
Query: 30 GFRCERCPGSQTSDGQTCR--TACS-ANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN--- 83
G+RC CP +G C C+ A+PCF G +P + C CP G+ G
Sbjct: 297 GYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCINTMPG--FHCEACPRGYKGTQVS 354
Query: 84 --GVECYRIS---CR-ANTCFQGVS--------CEETQYGPKCGSCPTGYVGDGRQ-C-- 126
G++ R S C + C G + C T KCG C G++G+ Q C
Sbjct: 355 GVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLP 414
Query: 127 QHVC--DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC---VDMDEC-DLIRPC- 179
C A PC C+ + C+ C G+ NG C D+D D PC
Sbjct: 415 ARTCHSPAHSPCHIHAHCLFERNGA-VSCQ-CNVGWAGNGNVCGTDTDIDGYPDQALPCM 472
Query: 180 DDLVSCRNEEXXXXXXXXXXXXXX-------SQGWRGTGNERRREHC-VDVDECADGRAN 231
D+ C+ + G G + ++C + ++
Sbjct: 473 DNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSDT 532
Query: 232 CPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRF 291
G C N P P+N G+ C V+ D+ K +P R
Sbjct: 533 DSFGDACDNCPNVPNNDQKDTDGNGEGDACDND--VDGDGIPNGLDNCPKVPNPLQTDRD 590
Query: 292 NAVCGFGQKCVCNTGWTGNGTVCGLDRDLDG---HPDEQLPCNEPRCKKDNCPDVSNSGQ 348
G G C + N T D DL G +E + + KDNCP + NS Q
Sbjct: 591 ED--GVGDAC-DSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQ 647
Query: 349 EXXXXXXXXXXXXXXXXXXXIPNF----PDNCPLTPNPDQLDDDEN 390
IP++ PDNC L PNP+Q D D N
Sbjct: 648 LDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGN 693
>AK223278-1|BAD96998.1| 956|Homo sapiens thrombospondin 3 precursor
variant protein.
Length = 956
Score = 580 bits (1433), Expect = e-165
Identities = 304/679 (44%), Positives = 372/679 (54%), Gaps = 37/679 (5%)
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXX 194
PC R CM P Y C CP G Q NG C D++EC PC SC N
Sbjct: 282 PCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCINTMPGFHC 341
Query: 195 XXXXXXXXXSQGWRGTGNERRR---EHCVDVDECADGR-ANCPRGRLCVNTPQYPSNPVS 250
+Q G G + R + C D+DEC DG C +C NT
Sbjct: 342 EACPRGYKGTQV-SGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTV-------- 392
Query: 251 SLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQK----CVCNTG 306
GS+ C PC + N ++ C P S C +A C F + C CN G
Sbjct: 393 ---GSFKCGPCRLGFLGNQSQGCL-PARTCHSPAHSPCH-IHAHCLFERNGAVSCQCNVG 447
Query: 307 WTGNGTVCGLDRDLDGHPDEQLPC--NEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXX 364
W GNG VCG D D+DG+PD+ LPC N CK+DNC NSGQE
Sbjct: 448 WAGNGNVCGTDTDIDGYPDQALPCMDNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDA 507
Query: 365 XXXXIPNFPDNCPLTPNPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXX 424
I N DNC L PN DQ + D +D G+ACDNCP N Q+
Sbjct: 508 DGDGIKNVEDNCRLFPNKDQQNSD---TDSFGDACDNCPNVPNNDQKDTDGNGERDACDN 564
Query: 425 XXXXXXIPNQVDNCPRKYNPQQDDMDSDGVGDVCDNCPRVRNTNQEDTDKDNVGDACXXX 484
IPN +DNCP+ NP Q D D DGVGD CD+CP + N Q D D D VGD C
Sbjct: 565 DVDGDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTN 624
Query: 485 XXXXXXXXXXXXXNCPLIPNSXXXXXXXXXXXXXXXXXXXXXXXXXXX----XNCQIVPN 540
NCP +PNS NC++VPN
Sbjct: 625 EDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPN 684
Query: 541 RDQKDSDNDGIGDACDNDIDGDRVINELDNCPTIRRYFERTSGTLMRCRQFTTVRLDPEG 600
+QKDSD +G+GD C++D D D V++ LD CP E TL R + TV LDPEG
Sbjct: 685 PNQKDSDGNGVGDVCEDDFDNDAVVDPLDVCP------ESAEVTLTDFRAYQTVVLDPEG 738
Query: 601 ESQQEPNWRVTDNGAEILQTLHSDPGLAVGFDSFGGVDYEGTIFVNTKIDDDYVGFIFGY 660
++Q +PNW V + G EI+QT++SDPGLAVG+ +F GVD+EGT VNT DDDY GF+F Y
Sbjct: 739 DAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSY 798
Query: 661 QSNKRFYVVMWKKDKQTYWQKTPFRAVAENGIQLKLVNSKTGPGKILRNALWNTNSTPDQ 720
Q + RFYVVMWK+ +QTYWQ TPFRAVA+ G+QLK V S +GPG+ LRNALW+T TPDQ
Sbjct: 799 QDSGRFYVVMWKQTEQTYWQATPFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQ 858
Query: 721 VTLLWKDPRNVGWREQTAYRWKLLHRPKIGLIRLKMYENNRLVADSGNTYDFTLKGGRLG 780
V LLW DPRNVGWR++T+YRW+LLHRP++G IR+K+YE +LVADSG D +++GGRLG
Sbjct: 859 VRLLWTDPRNVGWRDKTSYRWQLLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLG 918
Query: 781 VFCFSQEMIIWSNLLYKCN 799
VFCFSQE IIWSNL Y+CN
Sbjct: 919 VFCFSQENIIWSNLQYRCN 937
Score = 99.1 bits (236), Expect = 5e-20
Identities = 122/457 (26%), Positives = 162/457 (35%), Gaps = 74/457 (16%)
Query: 48 RTACSANPCFGGRVPCQDLPD-GRYQCGKCPSGFHGNGVECYRIS--CRANTCFQGVSCE 104
R+ CS NPCF G V C ++ + Y+CG CP G GNG C I+ A+ CF G SC
Sbjct: 275 RSHCSPNPCFRG-VDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCI 333
Query: 105 ETQYGPKCGSCPTGYVGD---------GRQCQHVCDAQKPC--GRERRCMPKS----TSP 149
T G C +CP GY G R + VC+ C G C P S T
Sbjct: 334 NTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVG 393
Query: 150 YYECEGCPSGYQWN-GYTCVDMDEC--DLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQG 206
++C C G+ N C+ C PC C E + G
Sbjct: 394 SFKCGPCRLGFLGNQSQGCLPARTCHSPAHSPCHIHAHCLFER------NGAVSCQCNVG 447
Query: 207 WRGTGNERRREHCVD--VDE---CADGRANCPRGRLCVNTPQYPSNPVSS---------- 251
W G GN + +D D+ C D +C + C+ TP +
Sbjct: 448 WAGNGNVCGTDTDIDGYPDQALPCMDNNKHCKQDN-CLLTPNSGQEDADNDGVGDQCDDD 506
Query: 252 LQGSYI-CVPCGGHYYVNTTRPCFDPDSLVKRCD--PSYCRRFNA-VCGFGQKCVCNTGW 307
G I V + N + D DS CD P+ G G++ C+
Sbjct: 507 ADGDGIKNVEDNCRLFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGERDACDNDV 566
Query: 308 TGNGTVCGLDRDLDGHPDEQLPCNEPRCKK--DNCPDVSNSGQEXXXXXXXXX--XXXXX 363
G+G GLD Q +E D+CP++SN Q
Sbjct: 567 DGDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNED 626
Query: 364 XXXXXIPNFPDNCPLTPNPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXX 423
+ DNCP PN QLD D +D G+ CD
Sbjct: 627 SDGDGHQDTKDNCPQLPNSSQLDSD---NDGLGDECDG-------------------DDD 664
Query: 424 XXXXXXXIPNQVDNCPRKYNPQQDDMDSDGVGDVCDN 460
+P DNC NP Q D D +GVGDVC++
Sbjct: 665 NDGIPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCED 701
Score = 64.9 bits (151), Expect = 1e-09
Identities = 101/406 (24%), Positives = 142/406 (34%), Gaps = 54/406 (13%)
Query: 30 GFRCERCPGSQTSDGQTCR--TACS-ANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN--- 83
G+RC CP +G C C+ A+PCF G +P + C CP G+ G
Sbjct: 297 GYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCINTMPG--FHCEACPRGYKGTQVS 354
Query: 84 --GVECYRIS---CR-ANTCFQGVS--------CEETQYGPKCGSCPTGYVGDGRQ-C-- 126
G++ R S C + C G + C T KCG C G++G+ Q C
Sbjct: 355 GVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLP 414
Query: 127 QHVC--DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC---VDMDEC-DLIRPC- 179
C A PC C+ + C+ C G+ NG C D+D D PC
Sbjct: 415 ARTCHSPAHSPCHIHAHCLFERNGA-VSCQ-CNVGWAGNGNVCGTDTDIDGYPDQALPCM 472
Query: 180 DDLVSCRNEEXXXXXXXXXXXXXX-------SQGWRGTGNERRREHC-VDVDECADGRAN 231
D+ C+ + G G + ++C + ++
Sbjct: 473 DNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSDT 532
Query: 232 CPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRF 291
G C N P P+N G+ C V+ D+ K +P R
Sbjct: 533 DSFGDACDNCPNVPNNDQKDTDGNGERDACDND--VDGDGIPNGLDNCPKVPNPLQTDRD 590
Query: 292 NAVCGFGQKCVCNTGWTGNGTVCGLDRDLDG---HPDEQLPCNEPRCKKDNCPDVSNSGQ 348
G G C + N T D DL G +E + + KDNCP + NS Q
Sbjct: 591 ED--GVGDAC-DSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQ 647
Query: 349 EXXXXXXXXXXXXXXXXXXXIPNF----PDNCPLTPNPDQLDDDEN 390
IP++ PDNC L PNP+Q D D N
Sbjct: 648 LDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGN 693
>BC113847-1|AAI13848.1| 956|Homo sapiens thrombospondin 3,
precursor protein.
Length = 956
Score = 579 bits (1429), Expect = e-164
Identities = 303/679 (44%), Positives = 371/679 (54%), Gaps = 37/679 (5%)
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXX 194
PC R CM P Y C CP G Q NG C D++EC PC SC N
Sbjct: 282 PCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCINTMPGFHC 341
Query: 195 XXXXXXXXXSQGWRGTGNERRR---EHCVDVDECADGR-ANCPRGRLCVNTPQYPSNPVS 250
+Q G G + R + C D+DEC DG C +C NT
Sbjct: 342 EACPRGYKGTQV-SGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTV-------- 392
Query: 251 SLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQK----CVCNTG 306
GS+ C PC + N ++ C P S C +A C F + C CN G
Sbjct: 393 ---GSFKCGPCRLGFLGNQSQGCL-PARTCHSPAHSPCH-IHAHCLFERNGAVSCQCNVG 447
Query: 307 WTGNGTVCGLDRDLDGHPDEQLPC--NEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXX 364
W GNG VCG D D+DG+PD+ LPC N CK+DNC NSGQE
Sbjct: 448 WAGNGNVCGTDTDIDGYPDQALPCMDNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDA 507
Query: 365 XXXXIPNFPDNCPLTPNPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXX 424
I N DNC L PN DQ + D +D G+ACDNCP N Q+
Sbjct: 508 DGDGIKNVEDNCRLFPNKDQQNSD---TDSFGDACDNCPNVPNNDQKDTDGNGEGDACDN 564
Query: 425 XXXXXXIPNQVDNCPRKYNPQQDDMDSDGVGDVCDNCPRVRNTNQEDTDKDNVGDACXXX 484
IPN +DNCP+ NP Q D D DGVGD CD+CP + N Q D D D VGD C
Sbjct: 565 DVDGDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTN 624
Query: 485 XXXXXXXXXXXXXNCPLIPNSXXXXXXXXXXXXXXXXXXXXXXXXXXX----XNCQIVPN 540
NCP +PNS NC++VPN
Sbjct: 625 EDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPN 684
Query: 541 RDQKDSDNDGIGDACDNDIDGDRVINELDNCPTIRRYFERTSGTLMRCRQFTTVRLDPEG 600
+QKDSD +G+GD C++D D D V++ LD CP E TL R + TV LDPEG
Sbjct: 685 PNQKDSDGNGVGDVCEDDFDNDAVVDPLDVCP------ESAEVTLTDFRAYQTVVLDPEG 738
Query: 601 ESQQEPNWRVTDNGAEILQTLHSDPGLAVGFDSFGGVDYEGTIFVNTKIDDDYVGFIFGY 660
++Q +PNW V + G EI+QT++SDPGLAVG+ +F GVD+EGT NT DDDY GF+F Y
Sbjct: 739 DAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHANTVTDDDYAGFLFSY 798
Query: 661 QSNKRFYVVMWKKDKQTYWQKTPFRAVAENGIQLKLVNSKTGPGKILRNALWNTNSTPDQ 720
Q + RFYVVMWK+ +QTYWQ TPFRAVA+ G+QLK V S +GPG+ LRNALW+T TPDQ
Sbjct: 799 QDSGRFYVVMWKQTEQTYWQATPFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQ 858
Query: 721 VTLLWKDPRNVGWREQTAYRWKLLHRPKIGLIRLKMYENNRLVADSGNTYDFTLKGGRLG 780
V LLW DPRNVGWR++T+YRW+LLHRP++G IR+K+YE +LVADSG D +++GGRLG
Sbjct: 859 VRLLWTDPRNVGWRDKTSYRWQLLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLG 918
Query: 781 VFCFSQEMIIWSNLLYKCN 799
VFCFSQE IIWSNL Y+CN
Sbjct: 919 VFCFSQENIIWSNLQYRCN 937
Score = 97.9 bits (233), Expect = 1e-19
Identities = 125/461 (27%), Positives = 162/461 (35%), Gaps = 82/461 (17%)
Query: 48 RTACSANPCFGGRVPCQDLPD-GRYQCGKCPSGFHGNGVECYRIS--CRANTCFQGVSCE 104
R+ CS NPCF G V C ++ + Y+CG CP G GNG C I+ A+ CF G SC
Sbjct: 275 RSHCSPNPCFRG-VDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCI 333
Query: 105 ETQYGPKCGSCPTGYVGD---------GRQCQHVCDAQKPC--GRERRCMPKS----TSP 149
T G C +CP GY G R + VC+ C G C P S T
Sbjct: 334 NTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVG 393
Query: 150 YYECEGCPSGYQWN-GYTCVDMDEC--DLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQG 206
++C C G+ N C+ C PC C E + G
Sbjct: 394 SFKCGPCRLGFLGNQSQGCLPARTCHSPAHSPCHIHAHCLFER------NGAVSCQCNVG 447
Query: 207 WRGTGNERRREHCVD--VDE---CADGRANCPRGRLCVNTPQYPSNPV-SSLQGSYICVP 260
W G GN + +D D+ C D +C + C+ TP + G
Sbjct: 448 WAGNGNVCGTDTDIDGYPDQALPCMDNNKHCKQDN-CLLTPNSGQEDADNDGVGDQCDDD 506
Query: 261 CGGHYYVNTTRPC-FDPDSLVKRCDP----SYCRRFNAVCGFGQKCVCNTGWTGNGTVCG 315
G N C P+ + D C V QK +T G G C
Sbjct: 507 ADGDGIKNVEDNCRLFPNKDQQNSDTDSFGDACDNCPNVPNNDQK---DTDGNGEGDACD 563
Query: 316 LDRDLDGHPDEQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDN 375
D D DG P+ DNCP V N Q + + D+
Sbjct: 564 NDVDGDGIPN----------GLDNCPKVPNPLQ-------------TDRDEDGVGDACDS 600
Query: 376 CPLTPNPDQLDDD------------ENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXX 423
CP NP Q D D ++ D + DNCP+ N Q
Sbjct: 601 CPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECD 660
Query: 424 XXXXXXXIPNQV----DNCPRKYNPQQDDMDSDGVGDVCDN 460
IP+ V DNC NP Q D D +GVGDVC++
Sbjct: 661 GDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCED 701
Score = 64.9 bits (151), Expect = 1e-09
Identities = 101/406 (24%), Positives = 142/406 (34%), Gaps = 54/406 (13%)
Query: 30 GFRCERCPGSQTSDGQTCR--TACS-ANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN--- 83
G+RC CP +G C C+ A+PCF G +P + C CP G+ G
Sbjct: 297 GYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCINTMPG--FHCEACPRGYKGTQVS 354
Query: 84 --GVECYRIS---CR-ANTCFQGVS--------CEETQYGPKCGSCPTGYVGDGRQ-C-- 126
G++ R S C + C G + C T KCG C G++G+ Q C
Sbjct: 355 GVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLP 414
Query: 127 QHVC--DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC---VDMDEC-DLIRPC- 179
C A PC C+ + C+ C G+ NG C D+D D PC
Sbjct: 415 ARTCHSPAHSPCHIHAHCLFERNGA-VSCQ-CNVGWAGNGNVCGTDTDIDGYPDQALPCM 472
Query: 180 DDLVSCRNEEXXXXXXXXXXXXXX-------SQGWRGTGNERRREHC-VDVDECADGRAN 231
D+ C+ + G G + ++C + ++
Sbjct: 473 DNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSDT 532
Query: 232 CPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRF 291
G C N P P+N G+ C V+ D+ K +P R
Sbjct: 533 DSFGDACDNCPNVPNNDQKDTDGNGEGDACDND--VDGDGIPNGLDNCPKVPNPLQTDRD 590
Query: 292 NAVCGFGQKCVCNTGWTGNGTVCGLDRDLDG---HPDEQLPCNEPRCKKDNCPDVSNSGQ 348
G G C + N T D DL G +E + + KDNCP + NS Q
Sbjct: 591 ED--GVGDAC-DSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQ 647
Query: 349 EXXXXXXXXXXXXXXXXXXXIPNF----PDNCPLTPNPDQLDDDEN 390
IP++ PDNC L PNP+Q D D N
Sbjct: 648 LDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGN 693
>BC125092-1|AAI25093.1| 757|Homo sapiens cartilage oligomeric
matrix protein protein.
Length = 757
Score = 577 bits (1425), Expect = e-164
Identities = 293/659 (44%), Positives = 363/659 (55%), Gaps = 39/659 (5%)
Query: 153 CEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX--XXXXXXSQGWRGT 210
C CP+G+ NG C D++EC+ PC V C N QG
Sbjct: 111 CGPCPAGFTGNGSHCTDVNECNA-HPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLA 169
Query: 211 GNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTT 270
+ ++ C D++EC G+ NC +C+NT +GS+ C PC + +
Sbjct: 170 FAKANKQVCTDINECETGQHNCVPNSVCINT-----------RGSFQCGPCQPGFVGDQA 218
Query: 271 RPC------FDPDSLVKRCDPSYCRRFNAVCGF----GQKCVCNTGWTGNGTVCGLDRDL 320
C F PD PS C +A C + CVC GW GNG +CG D DL
Sbjct: 219 SGCQRRAQRFCPDG-----SPSECHE-HADCVLERDGSRSCVCAVGWAGNGILCGRDTDL 272
Query: 321 DGHPDEQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDNCPLTP 380
DG PDE+L C E +C+KDNC V NSGQE +PN DNCPL
Sbjct: 273 DGFPDEKLRCPERQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGVPNEKDNCPLVR 332
Query: 381 NPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXXXXXXXXIPNQVDNCPR 440
NPDQ + DE D+ G+ACDNC N Q+ I NQ DNCPR
Sbjct: 333 NPDQRNTDE---DKWGDACDNCRSQKNDDQKDTDQDGRGDACDDDIDGDRIRNQADNCPR 389
Query: 441 KYNPQQDDMDSDGVGDVCDNCPRVRNTNQEDTDKDNVGDACXXXXXXXXXXXXXXXXNCP 500
N Q D D DG+GD CDNCP+ N +Q D D D VGDAC NCP
Sbjct: 390 VPNSDQKDSDGDGIGDACDNCPQKSNPDQADVDHDFVGDACDSDQDQDGDGHQDSRDNCP 449
Query: 501 LIPNSXXXXXXXXXXXXXXXXXXXXXXXXXXXXNCQIVPNRDQKDSDNDGIGDACDNDID 560
+PNS NC++VPN Q+D+D DG+GD C +D D
Sbjct: 450 TVPNSAQEDSDHDGQGDACDDDDDNDGVPDSRDNCRLVPNPGQEDADRDGVGDVCQDDFD 509
Query: 561 GDRVINELDNCPTIRRYFERTSGTLMRCRQFTTVRLDPEGESQQEPNWRVTDNGAEILQT 620
D+V++++D CP E TL R F TV LDPEG++Q +PNW V + G EI+QT
Sbjct: 510 ADKVVDKIDVCP------ENAEVTLTDFRAFQTVVLDPEGDAQIDPNWVVLNQGREIVQT 563
Query: 621 LHSDPGLAVGFDSFGGVDYEGTIFVNTKIDDDYVGFIFGYQSNKRFYVVMWKKDKQTYWQ 680
++SDPGLAVG+ +F GVD+EGT VNT DDDY GFIFGYQ + FYVVMWK+ +QTYWQ
Sbjct: 564 MNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQMEQTYWQ 623
Query: 681 KTPFRAVAENGIQLKLVNSKTGPGKILRNALWNTNSTPDQVTLLWKDPRNVGWREQTAYR 740
PFRAVAE GIQLK V S TGPG+ LRNALW+T T QV LLWKDPRNVGW+++ +YR
Sbjct: 624 ANPFRAVAEPGIQLKAVKSSTGPGEQLRNALWHTGDTESQVRLLWKDPRNVGWKDKKSYR 683
Query: 741 WKLLHRPKIGLIRLKMYENNRLVADSGNTYDFTLKGGRLGVFCFSQEMIIWSNLLYKCN 799
W L HRP++G IR++ YE LVADS D T++GGRLGVFCFSQE IIW+NL Y+CN
Sbjct: 684 WFLQHRPQVGYIRVRFYEGPELVADSNVVLDTTMRGGRLGVFCFSQENIIWANLRYRCN 742
Score = 144 bits (348), Expect = 1e-33
Identities = 132/439 (30%), Positives = 169/439 (38%), Gaps = 70/439 (15%)
Query: 90 ISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKPCGRERRCMPKST 147
+ C CF GV+C +T+ G +CG CP G+ G+G C V C+A PC RC+ +T
Sbjct: 89 LHCAPGFCFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNECNAH-PCFPRVRCI--NT 145
Query: 148 SPYYECEGCPSGY-------------QWNGYTCVDMDECDL-IRPCDDLVSCRNEEXXXX 193
SP + CE CP GY + N C D++EC+ C C N
Sbjct: 146 SPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQ 205
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGR-ANCPRGRLCVNTPQYPSNPVSSL 252
Q +G +RR + C DG + C CV + V ++
Sbjct: 206 CGPCQPGFVGDQ---ASGCQRRAQRF-----CPDGSPSECHEHADCVLERDGSRSCVCAV 257
Query: 253 QGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC--GFGQKCVCNTGWTGN 310
+ + CG +T F + L RC CR+ N V GQ+ V G
Sbjct: 258 GWAGNGILCGR----DTDLDGFPDEKL--RCPERQCRKDNCVTVPNSGQEDVDR---DGI 308
Query: 311 GTVCGLDRDLDGHPDEQLPC---NEPRCKK----------DNCPDVSNSGQEXXXXXXXX 357
G C D D DG P+E+ C P + DNC N Q+
Sbjct: 309 GDACDPDADGDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQKDTDQDGRG 368
Query: 358 XXXXXXXXXXXIPNFPDNCPLTPNPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXX 417
I N DNCP PN DQ D D D G+ACDNCP+ NP Q
Sbjct: 369 DACDDDIDGDRIRNQADNCPRVPNSDQKDSD---GDGIGDACDNCPQKSNPDQADVDHDF 425
Query: 418 XXXXXXXXXXXXXIPNQ--VDNCPRKYNPQQDDMDSDGVGDVC-------------DNCP 462
+Q DNCP N Q+D D DG GD C DNC
Sbjct: 426 VGDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPDSRDNCR 485
Query: 463 RVRNTNQEDTDKDNVGDAC 481
V N QED D+D VGD C
Sbjct: 486 LVPNPGQEDADRDGVGDVC 504
Score = 110 bits (264), Expect = 2e-23
Identities = 122/447 (27%), Positives = 157/447 (35%), Gaps = 68/447 (15%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYG 109
C+ CF G V C G +CG CP+GF GNG C ++ C A+ CF V C T G
Sbjct: 91 CAPGFCFPG-VACIQTESGA-RCGPCPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPG 148
Query: 110 PKCGSCPTGYVGDGRQ---------CQHVCDAQKPCGR-ERRCMPKS----TSPYYECEG 155
+C +CP GY G Q + VC C + C+P S T ++C
Sbjct: 149 FRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGP 208
Query: 156 CPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERR 215
C G+ + + P C + GW G G
Sbjct: 209 CQPGFVGDQASGCQR-RAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILCG 267
Query: 216 REHCVDVDECADGRANCP----RGRLCVNTPQYPSNPVSSLQGSYICVP-CGGHYYVNTT 270
R+ D+D D + CP R CV P V C P G N
Sbjct: 268 RD--TDLDGFPDEKLRCPERQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGVPNEK 325
Query: 271 RPC---FDPDSLVKRCDP--SYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPD 325
C +PD D C + QK +T G G C D D+DG
Sbjct: 326 DNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQK---DTDQDGRGDAC--DDDIDG--- 377
Query: 326 EQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDNCPLTPNPDQL 385
+ R + DNCP V NS Q+ I + DNCP NPDQ
Sbjct: 378 -----DRIRNQADNCPRVPNSDQK-------------DSDGDGIGDACDNCPQKSNPDQA 419
Query: 386 D------------DDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXXXXXXXXIPN 433
D D + D ++ DNCP N QE +P+
Sbjct: 420 DVDHDFVGDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPD 479
Query: 434 QVDNCPRKYNPQQDDMDSDGVGDVCDN 460
DNC NP Q+D D DGVGDVC +
Sbjct: 480 SRDNCRLVPNPGQEDADRDGVGDVCQD 506
Score = 63.3 bits (147), Expect = 3e-09
Identities = 51/172 (29%), Positives = 69/172 (40%), Gaps = 29/172 (16%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCR--TACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
G C+ T+ G RC CP T +G C C+A+PCF RV C + G ++C CP
Sbjct: 99 GVACIQTESGARCGPCPAGFTGNGSHCTDVNECNAHPCF-PRVRCINTSPG-FRCEACPP 156
Query: 79 GFHG-------------NGVECYRIS-CRA--NTCFQGVSCEETQYGPKCGSCPTGYVGD 122
G+ G N C I+ C + C C T+ +CG C G+VGD
Sbjct: 157 GYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGD 216
Query: 123 -----GRQCQHVCDAQKP--CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC 167
R+ Q C P C C+ + C C G+ NG C
Sbjct: 217 QASGCQRRAQRFCPDGSPSECHEHADCVLERDGS-RSCV-CAVGWAGNGILC 266
>BC110847-1|AAI10848.1| 757|Homo sapiens cartilage oligomeric
matrix protein protein.
Length = 757
Score = 577 bits (1425), Expect = e-164
Identities = 293/659 (44%), Positives = 363/659 (55%), Gaps = 39/659 (5%)
Query: 153 CEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX--XXXXXXSQGWRGT 210
C CP+G+ NG C D++EC+ PC V C N QG
Sbjct: 111 CGPCPAGFTGNGSHCTDVNECNA-HPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLA 169
Query: 211 GNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTT 270
+ ++ C D++EC G+ NC +C+NT +GS+ C PC + +
Sbjct: 170 FAKANKQVCTDINECETGQHNCVPNSVCINT-----------RGSFQCGPCQPGFVGDQA 218
Query: 271 RPC------FDPDSLVKRCDPSYCRRFNAVCGF----GQKCVCNTGWTGNGTVCGLDRDL 320
C F PD PS C +A C + CVC GW GNG +CG D DL
Sbjct: 219 SGCQRRAQRFCPDG-----SPSECHE-HADCVLERDGSRSCVCAVGWAGNGILCGRDTDL 272
Query: 321 DGHPDEQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDNCPLTP 380
DG PDE+L C E +C+KDNC V NSGQE +PN DNCPL
Sbjct: 273 DGFPDEKLRCPERQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGVPNEKDNCPLVR 332
Query: 381 NPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXXXXXXXXIPNQVDNCPR 440
NPDQ + DE D+ G+ACDNC N Q+ I NQ DNCPR
Sbjct: 333 NPDQRNTDE---DKWGDACDNCRSQKNDDQKDTDQDGRGDACDDDIDGDRIRNQADNCPR 389
Query: 441 KYNPQQDDMDSDGVGDVCDNCPRVRNTNQEDTDKDNVGDACXXXXXXXXXXXXXXXXNCP 500
N Q D D DG+GD CDNCP+ N +Q D D D VGDAC NCP
Sbjct: 390 VPNSDQKDSDGDGIGDACDNCPQKSNPDQADVDHDFVGDACDSDQDQDGDGHQDSRDNCP 449
Query: 501 LIPNSXXXXXXXXXXXXXXXXXXXXXXXXXXXXNCQIVPNRDQKDSDNDGIGDACDNDID 560
+PNS NC++VPN Q+D+D DG+GD C +D D
Sbjct: 450 TVPNSAQEDSDHDGQGDACDDDDDNDGVPDSRDNCRLVPNPGQEDADRDGVGDVCQDDFD 509
Query: 561 GDRVINELDNCPTIRRYFERTSGTLMRCRQFTTVRLDPEGESQQEPNWRVTDNGAEILQT 620
D+V++++D CP E TL R F TV LDPEG++Q +PNW V + G EI+QT
Sbjct: 510 ADKVVDKIDVCP------ENAEVTLTDFRAFQTVVLDPEGDAQIDPNWVVLNQGREIVQT 563
Query: 621 LHSDPGLAVGFDSFGGVDYEGTIFVNTKIDDDYVGFIFGYQSNKRFYVVMWKKDKQTYWQ 680
++SDPGLAVG+ +F GVD+EGT VNT DDDY GFIFGYQ + FYVVMWK+ +QTYWQ
Sbjct: 564 MNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQMEQTYWQ 623
Query: 681 KTPFRAVAENGIQLKLVNSKTGPGKILRNALWNTNSTPDQVTLLWKDPRNVGWREQTAYR 740
PFRAVAE GIQLK V S TGPG+ LRNALW+T T QV LLWKDPRNVGW+++ +YR
Sbjct: 624 ANPFRAVAEPGIQLKAVKSSTGPGEQLRNALWHTGDTESQVRLLWKDPRNVGWKDKKSYR 683
Query: 741 WKLLHRPKIGLIRLKMYENNRLVADSGNTYDFTLKGGRLGVFCFSQEMIIWSNLLYKCN 799
W L HRP++G IR++ YE LVADS D T++GGRLGVFCFSQE IIW+NL Y+CN
Sbjct: 684 WFLQHRPQVGYIRVRFYEGPELVADSNVVLDTTMRGGRLGVFCFSQENIIWANLRYRCN 742
Score = 144 bits (348), Expect = 1e-33
Identities = 132/439 (30%), Positives = 169/439 (38%), Gaps = 70/439 (15%)
Query: 90 ISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKPCGRERRCMPKST 147
+ C CF GV+C +T+ G +CG CP G+ G+G C V C+A PC RC+ +T
Sbjct: 89 LHCAPGFCFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNECNAH-PCFPRVRCI--NT 145
Query: 148 SPYYECEGCPSGY-------------QWNGYTCVDMDECDL-IRPCDDLVSCRNEEXXXX 193
SP + CE CP GY + N C D++EC+ C C N
Sbjct: 146 SPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQ 205
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGR-ANCPRGRLCVNTPQYPSNPVSSL 252
Q +G +RR + C DG + C CV + V ++
Sbjct: 206 CGPCQPGFVGDQ---ASGCQRRAQRF-----CPDGSPSECHEHADCVLERDGSRSCVCAV 257
Query: 253 QGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC--GFGQKCVCNTGWTGN 310
+ + CG +T F + L RC CR+ N V GQ+ V G
Sbjct: 258 GWAGNGILCGR----DTDLDGFPDEKL--RCPERQCRKDNCVTVPNSGQEDVDR---DGI 308
Query: 311 GTVCGLDRDLDGHPDEQLPC---NEPRCKK----------DNCPDVSNSGQEXXXXXXXX 357
G C D D DG P+E+ C P + DNC N Q+
Sbjct: 309 GDACDPDADGDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQKDTDQDGRG 368
Query: 358 XXXXXXXXXXXIPNFPDNCPLTPNPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXX 417
I N DNCP PN DQ D D D G+ACDNCP+ NP Q
Sbjct: 369 DACDDDIDGDRIRNQADNCPRVPNSDQKDSD---GDGIGDACDNCPQKSNPDQADVDHDF 425
Query: 418 XXXXXXXXXXXXXIPNQ--VDNCPRKYNPQQDDMDSDGVGDVC-------------DNCP 462
+Q DNCP N Q+D D DG GD C DNC
Sbjct: 426 VGDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPDSRDNCR 485
Query: 463 RVRNTNQEDTDKDNVGDAC 481
V N QED D+D VGD C
Sbjct: 486 LVPNPGQEDADRDGVGDVC 504
Score = 110 bits (264), Expect = 2e-23
Identities = 122/447 (27%), Positives = 157/447 (35%), Gaps = 68/447 (15%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYG 109
C+ CF G V C G +CG CP+GF GNG C ++ C A+ CF V C T G
Sbjct: 91 CAPGFCFPG-VACIQTESGA-RCGPCPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPG 148
Query: 110 PKCGSCPTGYVGDGRQ---------CQHVCDAQKPCGR-ERRCMPKS----TSPYYECEG 155
+C +CP GY G Q + VC C + C+P S T ++C
Sbjct: 149 FRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGP 208
Query: 156 CPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERR 215
C G+ + + P C + GW G G
Sbjct: 209 CQPGFVGDQASGCQR-RAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILCG 267
Query: 216 REHCVDVDECADGRANCP----RGRLCVNTPQYPSNPVSSLQGSYICVP-CGGHYYVNTT 270
R+ D+D D + CP R CV P V C P G N
Sbjct: 268 RD--TDLDGFPDEKLRCPERQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGVPNEK 325
Query: 271 RPC---FDPDSLVKRCDP--SYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPD 325
C +PD D C + QK +T G G C D D+DG
Sbjct: 326 DNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQK---DTDQDGRGDAC--DDDIDG--- 377
Query: 326 EQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDNCPLTPNPDQL 385
+ R + DNCP V NS Q+ I + DNCP NPDQ
Sbjct: 378 -----DRIRNQADNCPRVPNSDQK-------------DSDGDGIGDACDNCPQKSNPDQA 419
Query: 386 D------------DDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXXXXXXXXIPN 433
D D + D ++ DNCP N QE +P+
Sbjct: 420 DVDHDFVGDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPD 479
Query: 434 QVDNCPRKYNPQQDDMDSDGVGDVCDN 460
DNC NP Q+D D DGVGDVC +
Sbjct: 480 SRDNCRLVPNPGQEDADRDGVGDVCQD 506
Score = 63.3 bits (147), Expect = 3e-09
Identities = 51/172 (29%), Positives = 69/172 (40%), Gaps = 29/172 (16%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCR--TACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
G C+ T+ G RC CP T +G C C+A+PCF RV C + G ++C CP
Sbjct: 99 GVACIQTESGARCGPCPAGFTGNGSHCTDVNECNAHPCF-PRVRCINTSPG-FRCEACPP 156
Query: 79 GFHG-------------NGVECYRIS-CRA--NTCFQGVSCEETQYGPKCGSCPTGYVGD 122
G+ G N C I+ C + C C T+ +CG C G+VGD
Sbjct: 157 GYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGD 216
Query: 123 -----GRQCQHVCDAQKP--CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC 167
R+ Q C P C C+ + C C G+ NG C
Sbjct: 217 QASGCQRRAQRFCPDGSPSECHEHADCVLERDGS-RSCV-CAVGWAGNGILC 266
>AC003107-1|AAB86501.1| 817|Homo sapiens COMP_HUMAN protein.
Length = 817
Score = 577 bits (1425), Expect = e-164
Identities = 293/659 (44%), Positives = 363/659 (55%), Gaps = 39/659 (5%)
Query: 153 CEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX--XXXXXXSQGWRGT 210
C CP+G+ NG C D++EC+ PC V C N QG
Sbjct: 111 CGPCPAGFTGNGSHCTDVNECNA-HPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLA 169
Query: 211 GNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTT 270
+ ++ C D++EC G+ NC +C+NT +GS+ C PC + +
Sbjct: 170 FAKANKQVCTDINECETGQHNCVPNSVCINT-----------RGSFQCGPCQPGFVGDQA 218
Query: 271 RPC------FDPDSLVKRCDPSYCRRFNAVCGF----GQKCVCNTGWTGNGTVCGLDRDL 320
C F PD PS C +A C + CVC GW GNG +CG D DL
Sbjct: 219 SGCQRRAQRFCPDG-----SPSECHE-HADCVLERDGSRSCVCAVGWAGNGILCGRDTDL 272
Query: 321 DGHPDEQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDNCPLTP 380
DG PDE+L C E +C+KDNC V NSGQE +PN DNCPL
Sbjct: 273 DGFPDEKLRCPERQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGVPNEKDNCPLVR 332
Query: 381 NPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXXXXXXXXIPNQVDNCPR 440
NPDQ + DE D+ G+ACDNC N Q+ I NQ DNCPR
Sbjct: 333 NPDQRNTDE---DKWGDACDNCRSQKNDDQKDTDQDGRGDACDDDIDGDRIRNQADNCPR 389
Query: 441 KYNPQQDDMDSDGVGDVCDNCPRVRNTNQEDTDKDNVGDACXXXXXXXXXXXXXXXXNCP 500
N Q D D DG+GD CDNCP+ N +Q D D D VGDAC NCP
Sbjct: 390 VPNSDQKDSDGDGIGDACDNCPQKSNPDQADVDHDFVGDACDSDQDQDGDGHQDSRDNCP 449
Query: 501 LIPNSXXXXXXXXXXXXXXXXXXXXXXXXXXXXNCQIVPNRDQKDSDNDGIGDACDNDID 560
+PNS NC++VPN Q+D+D DG+GD C +D D
Sbjct: 450 TVPNSAQEDSDHDGQGDACDDDDDNDGVPDSRDNCRLVPNPGQEDADRDGVGDVCQDDFD 509
Query: 561 GDRVINELDNCPTIRRYFERTSGTLMRCRQFTTVRLDPEGESQQEPNWRVTDNGAEILQT 620
D+V++++D CP E TL R F TV LDPEG++Q +PNW V + G EI+QT
Sbjct: 510 ADKVVDKIDVCP------ENAEVTLTDFRAFQTVVLDPEGDAQIDPNWVVLNQGREIVQT 563
Query: 621 LHSDPGLAVGFDSFGGVDYEGTIFVNTKIDDDYVGFIFGYQSNKRFYVVMWKKDKQTYWQ 680
++SDPGLAVG+ +F GVD+EGT VNT DDDY GFIFGYQ + FYVVMWK+ +QTYWQ
Sbjct: 564 MNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQMEQTYWQ 623
Query: 681 KTPFRAVAENGIQLKLVNSKTGPGKILRNALWNTNSTPDQVTLLWKDPRNVGWREQTAYR 740
PFRAVAE GIQLK V S TGPG+ LRNALW+T T QV LLWKDPRNVGW+++ +YR
Sbjct: 624 ANPFRAVAEPGIQLKAVKSSTGPGEQLRNALWHTGDTESQVRLLWKDPRNVGWKDKKSYR 683
Query: 741 WKLLHRPKIGLIRLKMYENNRLVADSGNTYDFTLKGGRLGVFCFSQEMIIWSNLLYKCN 799
W L HRP++G IR++ YE LVADS D T++GGRLGVFCFSQE IIW+NL Y+CN
Sbjct: 684 WFLQHRPQVGYIRVRFYEGPELVADSNVVLDTTMRGGRLGVFCFSQENIIWANLRYRCN 742
Score = 144 bits (348), Expect = 1e-33
Identities = 132/439 (30%), Positives = 169/439 (38%), Gaps = 70/439 (15%)
Query: 90 ISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKPCGRERRCMPKST 147
+ C CF GV+C +T+ G +CG CP G+ G+G C V C+A PC RC+ +T
Sbjct: 89 LHCAPGFCFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNECNAH-PCFPRVRCI--NT 145
Query: 148 SPYYECEGCPSGY-------------QWNGYTCVDMDECDL-IRPCDDLVSCRNEEXXXX 193
SP + CE CP GY + N C D++EC+ C C N
Sbjct: 146 SPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQ 205
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGR-ANCPRGRLCVNTPQYPSNPVSSL 252
Q +G +RR + C DG + C CV + V ++
Sbjct: 206 CGPCQPGFVGDQ---ASGCQRRAQRF-----CPDGSPSECHEHADCVLERDGSRSCVCAV 257
Query: 253 QGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC--GFGQKCVCNTGWTGN 310
+ + CG +T F + L RC CR+ N V GQ+ V G
Sbjct: 258 GWAGNGILCGR----DTDLDGFPDEKL--RCPERQCRKDNCVTVPNSGQEDVDR---DGI 308
Query: 311 GTVCGLDRDLDGHPDEQLPC---NEPRCKK----------DNCPDVSNSGQEXXXXXXXX 357
G C D D DG P+E+ C P + DNC N Q+
Sbjct: 309 GDACDPDADGDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQKDTDQDGRG 368
Query: 358 XXXXXXXXXXXIPNFPDNCPLTPNPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXX 417
I N DNCP PN DQ D D D G+ACDNCP+ NP Q
Sbjct: 369 DACDDDIDGDRIRNQADNCPRVPNSDQKDSD---GDGIGDACDNCPQKSNPDQADVDHDF 425
Query: 418 XXXXXXXXXXXXXIPNQ--VDNCPRKYNPQQDDMDSDGVGDVC-------------DNCP 462
+Q DNCP N Q+D D DG GD C DNC
Sbjct: 426 VGDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPDSRDNCR 485
Query: 463 RVRNTNQEDTDKDNVGDAC 481
V N QED D+D VGD C
Sbjct: 486 LVPNPGQEDADRDGVGDVC 504
Score = 110 bits (264), Expect = 2e-23
Identities = 122/447 (27%), Positives = 157/447 (35%), Gaps = 68/447 (15%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYG 109
C+ CF G V C G +CG CP+GF GNG C ++ C A+ CF V C T G
Sbjct: 91 CAPGFCFPG-VACIQTESGA-RCGPCPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPG 148
Query: 110 PKCGSCPTGYVGDGRQ---------CQHVCDAQKPCGR-ERRCMPKS----TSPYYECEG 155
+C +CP GY G Q + VC C + C+P S T ++C
Sbjct: 149 FRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGP 208
Query: 156 CPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERR 215
C G+ + + P C + GW G G
Sbjct: 209 CQPGFVGDQASGCQR-RAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILCG 267
Query: 216 REHCVDVDECADGRANCP----RGRLCVNTPQYPSNPVSSLQGSYICVP-CGGHYYVNTT 270
R+ D+D D + CP R CV P V C P G N
Sbjct: 268 RD--TDLDGFPDEKLRCPERQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGVPNEK 325
Query: 271 RPC---FDPDSLVKRCDP--SYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPD 325
C +PD D C + QK +T G G C D D+DG
Sbjct: 326 DNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQK---DTDQDGRGDAC--DDDIDG--- 377
Query: 326 EQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDNCPLTPNPDQL 385
+ R + DNCP V NS Q+ I + DNCP NPDQ
Sbjct: 378 -----DRIRNQADNCPRVPNSDQK-------------DSDGDGIGDACDNCPQKSNPDQA 419
Query: 386 D------------DDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXXXXXXXXIPN 433
D D + D ++ DNCP N QE +P+
Sbjct: 420 DVDHDFVGDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPD 479
Query: 434 QVDNCPRKYNPQQDDMDSDGVGDVCDN 460
DNC NP Q+D D DGVGDVC +
Sbjct: 480 SRDNCRLVPNPGQEDADRDGVGDVCQD 506
Score = 63.3 bits (147), Expect = 3e-09
Identities = 51/172 (29%), Positives = 69/172 (40%), Gaps = 29/172 (16%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCR--TACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
G C+ T+ G RC CP T +G C C+A+PCF RV C + G ++C CP
Sbjct: 99 GVACIQTESGARCGPCPAGFTGNGSHCTDVNECNAHPCF-PRVRCINTSPG-FRCEACPP 156
Query: 79 GFHG-------------NGVECYRIS-CRA--NTCFQGVSCEETQYGPKCGSCPTGYVGD 122
G+ G N C I+ C + C C T+ +CG C G+VGD
Sbjct: 157 GYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGD 216
Query: 123 -----GRQCQHVCDAQKP--CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC 167
R+ Q C P C C+ + C C G+ NG C
Sbjct: 217 QASGCQRRAQRFCPDGSPSECHEHADCVLERDGS-RSCV-CAVGWAGNGILC 266
>AK223216-1|BAD96936.1| 757|Homo sapiens cartilage oligomeric
matrix protein precursor variant protein.
Length = 757
Score = 575 bits (1420), Expect = e-163
Identities = 292/659 (44%), Positives = 363/659 (55%), Gaps = 39/659 (5%)
Query: 153 CEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX--XXXXXXSQGWRGT 210
C CP+G+ NG C D++EC+ PC V C N QG
Sbjct: 111 CGPCPAGFTGNGSHCTDVNECNA-HPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLA 169
Query: 211 GNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTT 270
+ ++ C D++EC G+ NC +C++T +GS+ C PC + +
Sbjct: 170 FAKANKQVCTDINECETGQHNCVPNSVCIST-----------RGSFQCGPCQPGFVGDQA 218
Query: 271 RPC------FDPDSLVKRCDPSYCRRFNAVCGF----GQKCVCNTGWTGNGTVCGLDRDL 320
C F PD PS C +A C + CVC GW GNG +CG D DL
Sbjct: 219 SGCQRRAQRFCPDG-----SPSECHE-HADCVLERDGSRSCVCAVGWAGNGILCGRDTDL 272
Query: 321 DGHPDEQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDNCPLTP 380
DG PDE+L C E +C+KDNC V NSGQE +PN DNCPL
Sbjct: 273 DGFPDEKLRCPERQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGVPNEKDNCPLVR 332
Query: 381 NPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXXXXXXXXIPNQVDNCPR 440
NPDQ + DE D+ G+ACDNC N Q+ I NQ DNCPR
Sbjct: 333 NPDQRNTDE---DKWGDACDNCRSQKNDDQKDTDQDGRGDACDDDIDGDRIRNQADNCPR 389
Query: 441 KYNPQQDDMDSDGVGDVCDNCPRVRNTNQEDTDKDNVGDACXXXXXXXXXXXXXXXXNCP 500
N Q D D DG+GD CDNCP+ N +Q D D D VGDAC NCP
Sbjct: 390 VPNSDQKDSDGDGIGDACDNCPQKSNPDQADVDHDFVGDACDSDQDQNGDGHQDSRGNCP 449
Query: 501 LIPNSXXXXXXXXXXXXXXXXXXXXXXXXXXXXNCQIVPNRDQKDSDNDGIGDACDNDID 560
+PNS NC++VPN Q+D+D DG+GD C +D D
Sbjct: 450 TVPNSAQEDSDHDGQGDACDDDDDNDGVPDSRDNCRLVPNPGQEDADRDGVGDVCQDDFD 509
Query: 561 GDRVINELDNCPTIRRYFERTSGTLMRCRQFTTVRLDPEGESQQEPNWRVTDNGAEILQT 620
D+V++++D CP E TL R F TV LDPEG++Q +PNW V + G EI+QT
Sbjct: 510 ADKVVDKIDVCP------ENAEVTLTDFRAFQTVVLDPEGDAQIDPNWVVLNQGREIVQT 563
Query: 621 LHSDPGLAVGFDSFGGVDYEGTIFVNTKIDDDYVGFIFGYQSNKRFYVVMWKKDKQTYWQ 680
++SDPGLAVG+ +F GVD+EGT VNT DDDY GFIFGYQ + FYVVMWK+ +QTYWQ
Sbjct: 564 MNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQMEQTYWQ 623
Query: 681 KTPFRAVAENGIQLKLVNSKTGPGKILRNALWNTNSTPDQVTLLWKDPRNVGWREQTAYR 740
PFRAVAE GIQLK V S TGPG+ LRNALW+T T QV LLWKDPRNVGW+++ +YR
Sbjct: 624 ANPFRAVAEPGIQLKAVKSSTGPGEQLRNALWHTGDTESQVRLLWKDPRNVGWKDKKSYR 683
Query: 741 WKLLHRPKIGLIRLKMYENNRLVADSGNTYDFTLKGGRLGVFCFSQEMIIWSNLLYKCN 799
W L HRP++G IR++ YE LVADS D T++GGRLGVFCFSQE IIW+NL Y+CN
Sbjct: 684 WFLQHRPQVGYIRVRFYEGPELVADSNVVLDTTMRGGRLGVFCFSQENIIWANLRYRCN 742
Score = 140 bits (339), Expect = 2e-32
Identities = 128/436 (29%), Positives = 167/436 (38%), Gaps = 64/436 (14%)
Query: 90 ISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKPCGRERRCMPKST 147
+ C CF GV+C +T+ G +CG CP G+ G+G C V C+A PC RC+ +T
Sbjct: 89 LHCAPGFCFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNECNAH-PCFPRVRCI--NT 145
Query: 148 SPYYECEGCPSGYQWNGYTCVDMDECDLIRP-CDDLVSCRNEEXXXXXXXXXXXXXXS-- 204
SP + CE CP GY + V + + C D+ C + S
Sbjct: 146 SPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCISTRGSFQ 205
Query: 205 --------QGWRGTGNERRREHCVDVDECADGR-ANCPRGRLCVNTPQYPSNPVSSLQGS 255
G + +G +RR + C DG + C CV + V ++ +
Sbjct: 206 CGPCQPGFVGDQASGCQRRAQRF-----CPDGSPSECHEHADCVLERDGSRSCVCAVGWA 260
Query: 256 YICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC--GFGQKCVCNTGWTGNGTV 313
+ CG +T F + L RC CR+ N V GQ+ V G G
Sbjct: 261 GNGILCGR----DTDLDGFPDEKL--RCPERQCRKDNCVTVPNSGQEDVDR---DGIGDA 311
Query: 314 CGLDRDLDGHPDEQLPC---NEPRCKK----------DNCPDVSNSGQEXXXXXXXXXXX 360
C D D DG P+E+ C P + DNC N Q+
Sbjct: 312 CDPDADGDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQKDTDQDGRGDAC 371
Query: 361 XXXXXXXXIPNFPDNCPLTPNPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXXXXX 420
I N DNCP PN DQ D D D G+ACDNCP+ NP Q
Sbjct: 372 DDDIDGDRIRNQADNCPRVPNSDQKDSD---GDGIGDACDNCPQKSNPDQADVDHDFVGD 428
Query: 421 XXXXXXXXXXIPNQVD--NCPRKYNPQQDDMDSDGVGDVC-------------DNCPRVR 465
+Q NCP N Q+D D DG GD C DNC V
Sbjct: 429 ACDSDQDQNGDGHQDSRGNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPDSRDNCRLVP 488
Query: 466 NTNQEDTDKDNVGDAC 481
N QED D+D VGD C
Sbjct: 489 NPGQEDADRDGVGDVC 504
Score = 107 bits (258), Expect = 1e-22
Identities = 121/447 (27%), Positives = 156/447 (34%), Gaps = 68/447 (15%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYG 109
C+ CF G V C G +CG CP+GF GNG C ++ C A+ CF V C T G
Sbjct: 91 CAPGFCFPG-VACIQTESGA-RCGPCPAGFTGNGSHCTDVNECNAHPCFPRVRCINTSPG 148
Query: 110 PKCGSCPTGYVGDGRQ---------CQHVCDAQKPCGR-ERRCMPK----STSPYYECEG 155
+C +CP GY G Q + VC C + C+P ST ++C
Sbjct: 149 FRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCISTRGSFQCGP 208
Query: 156 CPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERR 215
C G+ + + P C + GW G G
Sbjct: 209 CQPGFVGDQASGCQR-RAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWAGNGILCG 267
Query: 216 REHCVDVDECADGRANCP----RGRLCVNTPQYPSNPVSSLQGSYICVP-CGGHYYVNTT 270
R+ D+D D + CP R CV P V C P G N
Sbjct: 268 RD--TDLDGFPDEKLRCPERQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGVPNEK 325
Query: 271 RPC---FDPDSLVKRCDP--SYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPD 325
C +PD D C + QK +T G G C D D+DG
Sbjct: 326 DNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQK---DTDQDGRGDAC--DDDIDG--- 377
Query: 326 EQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDNCPLTPNPDQL 385
+ R + DNCP V NS Q+ I + DNCP NPDQ
Sbjct: 378 -----DRIRNQADNCPRVPNSDQK-------------DSDGDGIGDACDNCPQKSNPDQA 419
Query: 386 D------------DDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXXXXXXXXIPN 433
D D + D ++ NCP N QE +P+
Sbjct: 420 DVDHDFVGDACDSDQDQNGDGHQDSRGNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPD 479
Query: 434 QVDNCPRKYNPQQDDMDSDGVGDVCDN 460
DNC NP Q+D D DGVGDVC +
Sbjct: 480 SRDNCRLVPNPGQEDADRDGVGDVCQD 506
Score = 63.3 bits (147), Expect = 3e-09
Identities = 51/172 (29%), Positives = 69/172 (40%), Gaps = 29/172 (16%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCR--TACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
G C+ T+ G RC CP T +G C C+A+PCF RV C + G ++C CP
Sbjct: 99 GVACIQTESGARCGPCPAGFTGNGSHCTDVNECNAHPCF-PRVRCINTSPG-FRCEACPP 156
Query: 79 GFHG-------------NGVECYRIS-CRA--NTCFQGVSCEETQYGPKCGSCPTGYVGD 122
G+ G N C I+ C + C C T+ +CG C G+VGD
Sbjct: 157 GYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCISTRGSFQCGPCQPGFVGD 216
Query: 123 -----GRQCQHVCDAQKP--CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC 167
R+ Q C P C C+ + C C G+ NG C
Sbjct: 217 QASGCQRRAQRFCPDGSPSECHEHADCVLERDGS-RSCV-CAVGWAGNGILC 266
>Z19585-1|CAA79635.1| 961|Homo sapiens thrombospondin-4 protein.
Length = 961
Score = 565 bits (1394), Expect = e-160
Identities = 299/680 (43%), Positives = 375/680 (55%), Gaps = 38/680 (5%)
Query: 130 CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEE 189
CD+ PC R +C ++C CP GY NG TC+D+DEC PC V C N
Sbjct: 290 CDSN-PCFRGVQCTDSRDG--FQCGPCPEGYTGNGITCIDVDECKY-HPCYPGVHCINLS 345
Query: 190 XXXXXXXXXXXXXXS--QGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSN 247
QG + + ++ C D+DEC +G C +CVNT
Sbjct: 346 PGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA--CVPNSICVNT------ 397
Query: 248 PVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQK----CVC 303
GSY C PC Y + R C + + + + C NA C ++ CVC
Sbjct: 398 -----LGSYRCGPCKPGYTGDQIRGC-KVERNCRNPELNPCS-VNAQCIEERQGDVTCVC 450
Query: 304 NTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXX 363
GW G+G +CG D D+D +PDE+LPC+ CKKDNC V NSGQE
Sbjct: 451 GVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDED 510
Query: 364 XXXXXIPNFPDNCPLTPNPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXX 423
I N DNC L N DQ + D+ D G+ACDNC N Q+
Sbjct: 511 ADGDGILNEQDNCVLIHNVDQRNSDK---DIFGDACDNCLSVLNNDQKDTDGDGRGDACD 567
Query: 424 XXXXXXXIPNQVDNCPRKYNPQQDDMDSDGVGDVCDNCPRVRNTNQEDTDKDNVGDACXX 483
I N +DNCP+ N Q D D DGVGD CD+CP V N NQ D D D VGD+C
Sbjct: 568 DDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDT 627
Query: 484 XXXXXXXXXXXXXXNCPLIPNSXXXXXXXXXXXXXXXXXXXXXXXXXXX----XNCQIVP 539
NCP + NS NC++VP
Sbjct: 628 NQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVP 687
Query: 540 NRDQKDSDNDGIGDACDNDIDGDRVINELDNCPTIRRYFERTSGTLMRCRQFTTVRLDPE 599
N Q+DS++DG+GD C++D D D+VI+ +D CP E TL R + TV LDPE
Sbjct: 688 NPAQEDSNSDGVGDICESDFDQDQVIDRIDVCP------ENAEVTLTDFRAYQTVGLDPE 741
Query: 600 GESQQEPNWRVTDNGAEILQTLHSDPGLAVGFDSFGGVDYEGTIFVNTKIDDDYVGFIFG 659
G++Q +PNW V + G EI+QT++SDPGLAVG+ +F GVD+EGT VNT+ DDDY GFIFG
Sbjct: 742 GDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFG 801
Query: 660 YQSNKRFYVVMWKKDKQTYWQKTPFRAVAENGIQLKLVNSKTGPGKILRNALWNTNSTPD 719
YQ + FYVVMWK+ +QTYWQ TPFRAVAE GIQLK V SKTGPG+ LRN+LW+T T D
Sbjct: 802 YQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSD 861
Query: 720 QVTLLWKDPRNVGWREQTAYRWKLLHRPKIGLIRLKMYENNRLVADSGNTYDFTLKGGRL 779
QV LLWKD RNVGW+++ +YRW L HRP++G IR++ YE + LVADSG T D T++GGRL
Sbjct: 862 QVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRL 921
Query: 780 GVFCFSQEMIIWSNLLYKCN 799
GVFCFSQE IIWSNL Y+CN
Sbjct: 922 GVFCFSQENIIWSNLKYRCN 941
Score = 105 bits (253), Expect = 5e-22
Identities = 121/453 (26%), Positives = 164/453 (36%), Gaps = 80/453 (17%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRI-SCRANTCFQGVSCEETQYG 109
C +NPCF G V C D DG +QCG CP G+ GNG+ C + C+ + C+ GV C G
Sbjct: 290 CDSNPCFRG-VQCTDSRDG-FQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPG 347
Query: 110 PKCGSCPTGYVGD---------GRQCQHVCDAQKPCGRERRCMPKS----TSPYYECEGC 156
+C +CP G+ G + + VC C R C+P S T Y C C
Sbjct: 348 FRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDEC-RNGACVPNSICVNTLGSYRCGPC 406
Query: 157 PSGYQWNGYTCVDMDECDLIRPC--DDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNER 214
GYT + C + R C +L C GW G G
Sbjct: 407 KP-----GYTGDQIRGCKVERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYIC 461
Query: 215 RREHCVDVDECADGRANCPRGRLCV--NTPQYPSNPVSSLQGSYICVPC----GGHYYVN 268
++ VD+D D C R C N P++ I C G +N
Sbjct: 462 GKD--VDIDSYPDEELPC-SARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILN 518
Query: 269 TTRPC-----FDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGH 323
C D + K C +V QK +T G G C D D+DG
Sbjct: 519 EQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQK---DTDGDGRGDAC--DDDMDGD 573
Query: 324 PDEQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDNCPLTPNPD 383
+ + DNCP N Q + + D+CP NP+
Sbjct: 574 GIKNI--------LDNCPKFPNRDQR-------------DKDGDGVGDACDSCPDVSNPN 612
Query: 384 QLDDD------------ENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXXXXXXXXI 431
Q D D ++ D ++ DNCP N Q I
Sbjct: 613 QSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGI 672
Query: 432 PNQV----DNCPRKYNPQQDDMDSDGVGDVCDN 460
P+ V DNC NP Q+D +SDGVGD+C++
Sbjct: 673 PDLVPPGPDNCRLVPNPAQEDSNSDGVGDICES 705
Score = 73.7 bits (173), Expect = 2e-12
Identities = 58/184 (31%), Positives = 77/184 (41%), Gaps = 29/184 (15%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGKCPS 78
G +C D+ GF+C CP T +G TC C +PC+ G V C +L G ++C CP
Sbjct: 298 GVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPG-VHCINLSPG-FRCDACPV 355
Query: 79 GFHGNGVECYRIS--------------CRANTCFQGVSCEETQYGPKCGSCPTGYVGD-- 122
GF G V+ IS CR C C T +CG C GY GD
Sbjct: 356 GFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQI 415
Query: 123 -GRQCQHVC--DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC---VDMDEC-DL 175
G + + C PC +C+ + C C G+ +GY C VD+D D
Sbjct: 416 RGCKVERNCRNPELNPCSVNAQCIEERQGD-VTCV-CGVGWAGDGYICGKDVDIDSYPDE 473
Query: 176 IRPC 179
PC
Sbjct: 474 ELPC 477
Score = 51.6 bits (118), Expect = 1e-05
Identities = 88/370 (23%), Positives = 125/370 (33%), Gaps = 56/370 (15%)
Query: 21 GERCVDTDQGFRCERCPGSQT-------------SDGQTCRTA--CSANPCFGGRVPCQD 65
G C++ GFRC+ CP T S+ Q C C C +
Sbjct: 338 GVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNT 397
Query: 66 LPDGRYQCGKCPSGFHGNGVECYRI--SCR---ANTCFQGVSCEETQYGPKCGSCPTGYV 120
L G Y+CG C G+ G+ + ++ +CR N C C E + G C G+
Sbjct: 398 L--GSYRCGPCKPGYTGDQIRGCKVERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWA 455
Query: 121 GDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN------GYTC-VDMDEC 173
GDG C D E C ++ C+ P+ Q + G C D D
Sbjct: 456 GDGYICGKDVDIDSYPDEELPCSARNCKK-DNCKYVPNSGQEDADRDGIGDACDEDADGD 514
Query: 174 DLIRPCDDLVSCRN------EEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECAD 227
++ D+ V N ++ + + T + R + C D D D
Sbjct: 515 GILNEQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRGDAC-DDDMDGD 573
Query: 228 GRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYV-NTTRPCFDPDSLVKRCDPS 286
G N + N P++P+ G + C V N + D D + CD +
Sbjct: 574 GIKN-----ILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTN 628
Query: 287 YCRRFNAVCGFGQKC--VCN-----TGWTGNGTVCGLDRDLDGHPDEQLPCNEPRCKKDN 339
+ C V N T G G C D D DG PD P DN
Sbjct: 629 QDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPP------GPDN 682
Query: 340 CPDVSNSGQE 349
C V N QE
Sbjct: 683 CRLVPNPAQE 692
>BC050456-1|AAH50456.1| 961|Homo sapiens thrombospondin 4 protein.
Length = 961
Score = 565 bits (1394), Expect = e-160
Identities = 299/680 (43%), Positives = 375/680 (55%), Gaps = 38/680 (5%)
Query: 130 CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEE 189
CD+ PC R +C ++C CP GY NG TC+D+DEC PC V C N
Sbjct: 290 CDSN-PCFRGVQCTDSRDG--FQCGPCPEGYTGNGITCIDVDECKY-HPCYPGVHCINLS 345
Query: 190 XXXXXXXXXXXXXXS--QGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSN 247
QG + + ++ C D+DEC +G C +CVNT
Sbjct: 346 PGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA--CVPNSICVNT------ 397
Query: 248 PVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQK----CVC 303
GSY C PC Y + R C + + + + C NA C ++ CVC
Sbjct: 398 -----LGSYRCGPCKPGYTGDQIRGC-KAERNCRNPELNPCS-VNAQCIEERQGDVTCVC 450
Query: 304 NTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXX 363
GW G+G +CG D D+D +PDE+LPC+ CKKDNC V NSGQE
Sbjct: 451 GVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDED 510
Query: 364 XXXXXIPNFPDNCPLTPNPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXX 423
I N DNC L N DQ + D+ D G+ACDNC N Q+
Sbjct: 511 ADGDGILNEQDNCVLIHNVDQRNSDK---DIFGDACDNCLSVLNNDQKDTDGDGRGDACD 567
Query: 424 XXXXXXXIPNQVDNCPRKYNPQQDDMDSDGVGDVCDNCPRVRNTNQEDTDKDNVGDACXX 483
I N +DNCP+ N Q D D DGVGD CD+CP V N NQ D D D VGD+C
Sbjct: 568 DDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDT 627
Query: 484 XXXXXXXXXXXXXXNCPLIPNSXXXXXXXXXXXXXXXXXXXXXXXXXXX----XNCQIVP 539
NCP + NS NC++VP
Sbjct: 628 NQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVP 687
Query: 540 NRDQKDSDNDGIGDACDNDIDGDRVINELDNCPTIRRYFERTSGTLMRCRQFTTVRLDPE 599
N Q+DS++DG+GD C++D D D+VI+ +D CP E TL R + TV LDPE
Sbjct: 688 NPAQEDSNSDGVGDICESDFDQDQVIDRIDVCP------ENAEVTLTDFRAYQTVVLDPE 741
Query: 600 GESQQEPNWRVTDNGAEILQTLHSDPGLAVGFDSFGGVDYEGTIFVNTKIDDDYVGFIFG 659
G++Q +PNW V + G EI+QT++SDPGLAVG+ +F GVD+EGT VNT+ DDDY GFIFG
Sbjct: 742 GDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFG 801
Query: 660 YQSNKRFYVVMWKKDKQTYWQKTPFRAVAENGIQLKLVNSKTGPGKILRNALWNTNSTPD 719
YQ + FYVVMWK+ +QTYWQ TPFRAVAE GIQLK V SKTGPG+ LRN+LW+T T D
Sbjct: 802 YQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSD 861
Query: 720 QVTLLWKDPRNVGWREQTAYRWKLLHRPKIGLIRLKMYENNRLVADSGNTYDFTLKGGRL 779
QV LLWKD RNVGW+++ +YRW L HRP++G IR++ YE + LVADSG T D T++GGRL
Sbjct: 862 QVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRL 921
Query: 780 GVFCFSQEMIIWSNLLYKCN 799
GVFCFSQE IIWSNL Y+CN
Sbjct: 922 GVFCFSQENIIWSNLKYRCN 941
Score = 105 bits (251), Expect = 8e-22
Identities = 121/453 (26%), Positives = 163/453 (35%), Gaps = 80/453 (17%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRI-SCRANTCFQGVSCEETQYG 109
C +NPCF G V C D DG +QCG CP G+ GNG+ C + C+ + C+ GV C G
Sbjct: 290 CDSNPCFRG-VQCTDSRDG-FQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPG 347
Query: 110 PKCGSCPTGYVGD---------GRQCQHVCDAQKPCGRERRCMPKS----TSPYYECEGC 156
+C +CP G+ G + + VC C R C+P S T Y C C
Sbjct: 348 FRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDEC-RNGACVPNSICVNTLGSYRCGPC 406
Query: 157 PSGYQWNGYTCVDMDECDLIRPC--DDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNER 214
GYT + C R C +L C GW G G
Sbjct: 407 KP-----GYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYIC 461
Query: 215 RREHCVDVDECADGRANCPRGRLCV--NTPQYPSNPVSSLQGSYICVPC----GGHYYVN 268
++ VD+D D C R C N P++ I C G +N
Sbjct: 462 GKD--VDIDSYPDEELPC-SARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILN 518
Query: 269 TTRPC-----FDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGH 323
C D + K C +V QK +T G G C D D+DG
Sbjct: 519 EQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQK---DTDGDGRGDAC--DDDMDGD 573
Query: 324 PDEQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDNCPLTPNPD 383
+ + DNCP N Q + + D+CP NP+
Sbjct: 574 GIKNI--------LDNCPKFPNRDQR-------------DKDGDGVGDACDSCPDVSNPN 612
Query: 384 QLDDD------------ENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXXXXXXXXI 431
Q D D ++ D ++ DNCP N Q I
Sbjct: 613 QSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGI 672
Query: 432 PNQV----DNCPRKYNPQQDDMDSDGVGDVCDN 460
P+ V DNC NP Q+D +SDGVGD+C++
Sbjct: 673 PDLVPPGPDNCRLVPNPAQEDSNSDGVGDICES 705
Score = 74.1 bits (174), Expect = 2e-12
Identities = 58/184 (31%), Positives = 77/184 (41%), Gaps = 29/184 (15%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGKCPS 78
G +C D+ GF+C CP T +G TC C +PC+ G V C +L G ++C CP
Sbjct: 298 GVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPG-VHCINLSPG-FRCDACPV 355
Query: 79 GFHGNGVECYRIS--------------CRANTCFQGVSCEETQYGPKCGSCPTGYVGD-- 122
GF G V+ IS CR C C T +CG C GY GD
Sbjct: 356 GFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQI 415
Query: 123 -GRQCQHVC--DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC---VDMDEC-DL 175
G + + C PC +C+ + C C G+ +GY C VD+D D
Sbjct: 416 RGCKAERNCRNPELNPCSVNAQCIEERQGD-VTCV-CGVGWAGDGYICGKDVDIDSYPDE 473
Query: 176 IRPC 179
PC
Sbjct: 474 ELPC 477
Score = 50.0 bits (114), Expect = 3e-05
Identities = 88/370 (23%), Positives = 124/370 (33%), Gaps = 56/370 (15%)
Query: 21 GERCVDTDQGFRCERCPGSQT-------------SDGQTCRTA--CSANPCFGGRVPCQD 65
G C++ GFRC+ CP T S+ Q C C C +
Sbjct: 338 GVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNT 397
Query: 66 LPDGRYQCGKCPSGFHGNGVECYRI--SCR---ANTCFQGVSCEETQYGPKCGSCPTGYV 120
L G Y+CG C G+ G+ + + +CR N C C E + G C G+
Sbjct: 398 L--GSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWA 455
Query: 121 GDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN------GYTC-VDMDEC 173
GDG C D E C ++ C+ P+ Q + G C D D
Sbjct: 456 GDGYICGKDVDIDSYPDEELPCSARNCKK-DNCKYVPNSGQEDADRDGIGDACDEDADGD 514
Query: 174 DLIRPCDDLVSCRN------EEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECAD 227
++ D+ V N ++ + + T + R + C D D D
Sbjct: 515 GILNEQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRGDAC-DDDMDGD 573
Query: 228 GRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYV-NTTRPCFDPDSLVKRCDPS 286
G N + N P++P+ G + C V N + D D + CD +
Sbjct: 574 GIKN-----ILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTN 628
Query: 287 YCRRFNAVCGFGQKC--VCN-----TGWTGNGTVCGLDRDLDGHPDEQLPCNEPRCKKDN 339
+ C V N T G G C D D DG PD P DN
Sbjct: 629 QDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPP------GPDN 682
Query: 340 CPDVSNSGQE 349
C V N QE
Sbjct: 683 CRLVPNPAQE 692
>AY566253-1|AAS66982.1| 961|Homo sapiens thrombospondin 4 protein.
Length = 961
Score = 565 bits (1394), Expect = e-160
Identities = 299/680 (43%), Positives = 375/680 (55%), Gaps = 38/680 (5%)
Query: 130 CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEE 189
CD+ PC R +C ++C CP GY NG TC+D+DEC PC V C N
Sbjct: 290 CDSN-PCFRGVQCTDSRDG--FQCGPCPEGYTGNGITCIDVDECKY-HPCYPGVHCINLS 345
Query: 190 XXXXXXXXXXXXXXS--QGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSN 247
QG + + ++ C D+DEC +G C +CVNT
Sbjct: 346 PGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA--CVPNSICVNT------ 397
Query: 248 PVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQK----CVC 303
GSY C PC Y + R C + + + + C NA C ++ CVC
Sbjct: 398 -----LGSYRCGPCKPGYTGDQIRGC-KAERNCRNPELNPCS-VNAQCIEERQGDVTCVC 450
Query: 304 NTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXX 363
GW G+G +CG D D+D +PDE+LPC+ CKKDNC V NSGQE
Sbjct: 451 GVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDED 510
Query: 364 XXXXXIPNFPDNCPLTPNPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXX 423
I N DNC L N DQ + D+ D G+ACDNC N Q+
Sbjct: 511 ADGDGILNEQDNCVLIHNVDQRNSDK---DIFGDACDNCLSVLNNDQKDTDGDGRGDACD 567
Query: 424 XXXXXXXIPNQVDNCPRKYNPQQDDMDSDGVGDVCDNCPRVRNTNQEDTDKDNVGDACXX 483
I N +DNCP+ N Q D D DGVGD CD+CP V N NQ D D D VGD+C
Sbjct: 568 DDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDT 627
Query: 484 XXXXXXXXXXXXXXNCPLIPNSXXXXXXXXXXXXXXXXXXXXXXXXXXX----XNCQIVP 539
NCP + NS NC++VP
Sbjct: 628 NQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVP 687
Query: 540 NRDQKDSDNDGIGDACDNDIDGDRVINELDNCPTIRRYFERTSGTLMRCRQFTTVRLDPE 599
N Q+DS++DG+GD C++D D D+VI+ +D CP E TL R + TV LDPE
Sbjct: 688 NPAQEDSNSDGVGDICESDFDQDQVIDRIDVCP------ENAEVTLTDFRAYQTVVLDPE 741
Query: 600 GESQQEPNWRVTDNGAEILQTLHSDPGLAVGFDSFGGVDYEGTIFVNTKIDDDYVGFIFG 659
G++Q +PNW V + G EI+QT++SDPGLAVG+ +F GVD+EGT VNT+ DDDY GFIFG
Sbjct: 742 GDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFG 801
Query: 660 YQSNKRFYVVMWKKDKQTYWQKTPFRAVAENGIQLKLVNSKTGPGKILRNALWNTNSTPD 719
YQ + FYVVMWK+ +QTYWQ TPFRAVAE GIQLK V SKTGPG+ LRN+LW+T T D
Sbjct: 802 YQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSD 861
Query: 720 QVTLLWKDPRNVGWREQTAYRWKLLHRPKIGLIRLKMYENNRLVADSGNTYDFTLKGGRL 779
QV LLWKD RNVGW+++ +YRW L HRP++G IR++ YE + LVADSG T D T++GGRL
Sbjct: 862 QVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRL 921
Query: 780 GVFCFSQEMIIWSNLLYKCN 799
GVFCFSQE IIWSNL Y+CN
Sbjct: 922 GVFCFSQENIIWSNLKYRCN 941
Score = 105 bits (251), Expect = 8e-22
Identities = 121/453 (26%), Positives = 163/453 (35%), Gaps = 80/453 (17%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRI-SCRANTCFQGVSCEETQYG 109
C +NPCF G V C D DG +QCG CP G+ GNG+ C + C+ + C+ GV C G
Sbjct: 290 CDSNPCFRG-VQCTDSRDG-FQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPG 347
Query: 110 PKCGSCPTGYVGD---------GRQCQHVCDAQKPCGRERRCMPKS----TSPYYECEGC 156
+C +CP G+ G + + VC C R C+P S T Y C C
Sbjct: 348 FRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDEC-RNGACVPNSICVNTLGSYRCGPC 406
Query: 157 PSGYQWNGYTCVDMDECDLIRPC--DDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNER 214
GYT + C R C +L C GW G G
Sbjct: 407 KP-----GYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYIC 461
Query: 215 RREHCVDVDECADGRANCPRGRLCV--NTPQYPSNPVSSLQGSYICVPC----GGHYYVN 268
++ VD+D D C R C N P++ I C G +N
Sbjct: 462 GKD--VDIDSYPDEELPC-SARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILN 518
Query: 269 TTRPC-----FDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGH 323
C D + K C +V QK +T G G C D D+DG
Sbjct: 519 EQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQK---DTDGDGRGDAC--DDDMDGD 573
Query: 324 PDEQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDNCPLTPNPD 383
+ + DNCP N Q + + D+CP NP+
Sbjct: 574 GIKNI--------LDNCPKFPNRDQR-------------DKDGDGVGDACDSCPDVSNPN 612
Query: 384 QLDDD------------ENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXXXXXXXXI 431
Q D D ++ D ++ DNCP N Q I
Sbjct: 613 QSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGI 672
Query: 432 PNQV----DNCPRKYNPQQDDMDSDGVGDVCDN 460
P+ V DNC NP Q+D +SDGVGD+C++
Sbjct: 673 PDLVPPGPDNCRLVPNPAQEDSNSDGVGDICES 705
Score = 74.1 bits (174), Expect = 2e-12
Identities = 58/184 (31%), Positives = 77/184 (41%), Gaps = 29/184 (15%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGKCPS 78
G +C D+ GF+C CP T +G TC C +PC+ G V C +L G ++C CP
Sbjct: 298 GVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPG-VHCINLSPG-FRCDACPV 355
Query: 79 GFHGNGVECYRIS--------------CRANTCFQGVSCEETQYGPKCGSCPTGYVGD-- 122
GF G V+ IS CR C C T +CG C GY GD
Sbjct: 356 GFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQI 415
Query: 123 -GRQCQHVC--DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC---VDMDEC-DL 175
G + + C PC +C+ + C C G+ +GY C VD+D D
Sbjct: 416 RGCKAERNCRNPELNPCSVNAQCIEERQGD-VTCV-CGVGWAGDGYICGKDVDIDSYPDE 473
Query: 176 IRPC 179
PC
Sbjct: 474 ELPC 477
Score = 50.0 bits (114), Expect = 3e-05
Identities = 88/370 (23%), Positives = 124/370 (33%), Gaps = 56/370 (15%)
Query: 21 GERCVDTDQGFRCERCPGSQT-------------SDGQTCRTA--CSANPCFGGRVPCQD 65
G C++ GFRC+ CP T S+ Q C C C +
Sbjct: 338 GVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNT 397
Query: 66 LPDGRYQCGKCPSGFHGNGVECYRI--SCR---ANTCFQGVSCEETQYGPKCGSCPTGYV 120
L G Y+CG C G+ G+ + + +CR N C C E + G C G+
Sbjct: 398 L--GSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWA 455
Query: 121 GDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN------GYTC-VDMDEC 173
GDG C D E C ++ C+ P+ Q + G C D D
Sbjct: 456 GDGYICGKDVDIDSYPDEELPCSARNCKK-DNCKYVPNSGQEDADRDGIGDACDEDADGD 514
Query: 174 DLIRPCDDLVSCRN------EEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECAD 227
++ D+ V N ++ + + T + R + C D D D
Sbjct: 515 GILNEQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRGDAC-DDDMDGD 573
Query: 228 GRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYV-NTTRPCFDPDSLVKRCDPS 286
G N + N P++P+ G + C V N + D D + CD +
Sbjct: 574 GIKN-----ILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTN 628
Query: 287 YCRRFNAVCGFGQKC--VCN-----TGWTGNGTVCGLDRDLDGHPDEQLPCNEPRCKKDN 339
+ C V N T G G C D D DG PD P DN
Sbjct: 629 QDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPP------GPDN 682
Query: 340 CPDVSNSGQE 349
C V N QE
Sbjct: 683 CRLVPNPAQE 692
>BC018786-1|AAH18786.1| 592|Homo sapiens Similar to thrombospondin
3 protein.
Length = 592
Score = 551 bits (1359), Expect = e-156
Identities = 277/595 (46%), Positives = 342/595 (57%), Gaps = 33/595 (5%)
Query: 216 REHCVDVDECADGR-ANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCF 274
++ C D+DEC DG C +C NT GS+ C PC + N ++ C
Sbjct: 1 KQVCNDIDECNDGNNGGCDPNSICTNTV-----------GSFKCGPCRLGFLGNQSQGCL 49
Query: 275 DPDSLVKRCDPSYCRRFNAVCGFGQK----CVCNTGWTGNGTVCGLDRDLDGHPDEQLPC 330
P S C +A C F + C CN GW GNG VCG D D+DG+PD+ LPC
Sbjct: 50 -PARTCHSPAHSPCH-IHAHCLFERNGAVSCQCNVGWAGNGNVCGTDTDIDGYPDQALPC 107
Query: 331 --NEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDNCPLTPNPDQLDDD 388
N CK+DNC NSGQE I N DNC L PN DQ + D
Sbjct: 108 MDNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSD 167
Query: 389 ENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXXXXXXXXIPNQVDNCPRKYNPQQDD 448
+D G+ACDNCP N Q+ IPN +DNCP+ NP Q D
Sbjct: 168 ---TDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPKVPNPLQTD 224
Query: 449 MDSDGVGDVCDNCPRVRNTNQEDTDKDNVGDACXXXXXXXXXXXXXXXXNCPLIPNSXXX 508
D DGVGD CD+CP + N Q D D D VGD C NCP +PNS
Sbjct: 225 RDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQL 284
Query: 509 XXXXXXXXXXXXXXXXXXXXXXXX----XNCQIVPNRDQKDSDNDGIGDACDNDIDGDRV 564
NC++VPN +QKDSD +G+GD C++D D D V
Sbjct: 285 DSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCEDDFDNDAV 344
Query: 565 INELDNCPTIRRYFERTSGTLMRCRQFTTVRLDPEGESQQEPNWRVTDNGAEILQTLHSD 624
++ LD CP E TL R + TV LDPEG++Q +PNW V + G EI+QT++SD
Sbjct: 345 VDPLDVCP------ESAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSD 398
Query: 625 PGLAVGFDSFGGVDYEGTIFVNTKIDDDYVGFIFGYQSNKRFYVVMWKKDKQTYWQKTPF 684
PGLAVG+ +F GVD+EGT VNT DDDY GF+F YQ + RFYVVMWK+ +QTYWQ TPF
Sbjct: 399 PGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQATPF 458
Query: 685 RAVAENGIQLKLVNSKTGPGKILRNALWNTNSTPDQVTLLWKDPRNVGWREQTAYRWKLL 744
RAVA+ G+QLK V S +GPG+ LRNALW+T TPDQV LLW DPRNVGWR++T+YRW+LL
Sbjct: 459 RAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSYRWQLL 518
Query: 745 HRPKIGLIRLKMYENNRLVADSGNTYDFTLKGGRLGVFCFSQEMIIWSNLLYKCN 799
HRP++G IR+K+YE +LVADSG D +++GGRLGVFCFSQE IIWSNL Y+CN
Sbjct: 519 HRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCN 573
>BC113846-1|AAI13847.1| 485|Homo sapiens THBS3 protein protein.
Length = 485
Score = 484 bits (1194), Expect = e-136
Identities = 233/473 (49%), Positives = 285/473 (60%), Gaps = 13/473 (2%)
Query: 331 NEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDNCPLTPNPDQLDDDEN 390
N CK+DNC NSGQE I N DNC L PN DQ + D
Sbjct: 3 NNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSD-- 60
Query: 391 KSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXXXXXXXXIPNQVDNCPRKYNPQQDDMD 450
+D G+ACDNCP N Q+ IPN +DNCP+ NP Q D D
Sbjct: 61 -TDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPKVPNPLQTDRD 119
Query: 451 SDGVGDVCDNCPRVRNTNQEDTDKDNVGDACXXXXXXXXXXXXXXXXNCPLIPNSXXXXX 510
DGVGD CD+CP + N Q D D D VGD C NCP +PNS
Sbjct: 120 EDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQLDS 179
Query: 511 XXXXXXXXXXXXXXXXXXXXXX----XNCQIVPNRDQKDSDNDGIGDACDNDIDGDRVIN 566
NC++VPN +QKDSD +G+GD C++D D D V++
Sbjct: 180 DNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCEDDFDNDAVVD 239
Query: 567 ELDNCPTIRRYFERTSGTLMRCRQFTTVRLDPEGESQQEPNWRVTDNGAEILQTLHSDPG 626
LD CP E TL R + TV LDPEG++Q +PNW V + G EI+QT++SDPG
Sbjct: 240 PLDVCP------ESAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPG 293
Query: 627 LAVGFDSFGGVDYEGTIFVNTKIDDDYVGFIFGYQSNKRFYVVMWKKDKQTYWQKTPFRA 686
LAVG+ +F GVD+EGT VNT DDDY GF+F YQ + RFYVVMWK+ +QTYWQ TPFRA
Sbjct: 294 LAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQATPFRA 353
Query: 687 VAENGIQLKLVNSKTGPGKILRNALWNTNSTPDQVTLLWKDPRNVGWREQTAYRWKLLHR 746
VA+ G+QLK V S +GPG+ LRNALW+T TPDQV LLW DPRNVGWR++T+YRW+LLHR
Sbjct: 354 VAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSYRWQLLHR 413
Query: 747 PKIGLIRLKMYENNRLVADSGNTYDFTLKGGRLGVFCFSQEMIIWSNLLYKCN 799
P++G IR+K+YE +LVADSG D +++GGRLGVFCFSQE IIWSNL Y+CN
Sbjct: 414 PQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCN 466
Score = 44.0 bits (99), Expect = 0.002
Identities = 28/84 (33%), Positives = 34/84 (40%), Gaps = 12/84 (14%)
Query: 311 GTVCGLDRDLDGHPDEQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIP 370
G VC + D DG + KDNCP + NS Q IP
Sbjct: 147 GDVCDTNEDSDGDGHQDT--------KDNCPQLPNSSQLDSDNDGLGDECDGDDDNDGIP 198
Query: 371 NF----PDNCPLTPNPDQLDDDEN 390
++ PDNC L PNP+Q D D N
Sbjct: 199 DYVPPGPDNCRLVPNPNQKDSDGN 222
>X14787-1|CAA32889.1| 1170|Homo sapiens precursor polypeptide (AA -31
to 1139) protein.
Length = 1170
Score = 481 bits (1187), Expect = e-135
Identities = 231/502 (46%), Positives = 290/502 (57%), Gaps = 12/502 (2%)
Query: 300 KCVCNTGWTGNGTVCGLDRDLDGHPDEQLPC--NEP-RCKKDNCPDVSNSGQEXXXXXXX 356
+C C G+ GNG +CG D DLDG P+E L C N CKKDNCP++ NSGQE
Sbjct: 675 RCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPNLPNSGQEDYDKDGI 734
Query: 357 XXXXXXXXXXXXIPNFPDNCPLTPNPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXX 416
IP+ DNCP NP Q D D D+ G+ CDNCP ++NP Q
Sbjct: 735 GDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDR---DDVGDRCDNCPYNHNPDQADTDNN 791
Query: 417 XXXXXXXXXXXXXXIPNQVDNCPRKYNPQQDDMDSDGVGDVCDNCPRVRNTNQEDTDKDN 476
I N+ DNC YN Q D D DGVGD CDNCP N +Q D+D D
Sbjct: 792 GEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDR 851
Query: 477 VGDACXXXXXXXXXXXXXXXXNCPLIPNSXXXXXXXXXXXXXXXXXXXXXXXXXXXXNCQ 536
+GD C NCP +PN+ NC+
Sbjct: 852 IGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPDDKDNCR 911
Query: 537 IVPNRDQKDSDNDGIGDACDNDIDGDRVINELDNCPTIRRYFERTSGTLMRCRQFTTVRL 596
+VPN DQKDSD DG GDAC +D D D V + D CP E + R+F + L
Sbjct: 912 LVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICP------ENVDISETDFRRFQMIPL 965
Query: 597 DPEGESQQEPNWRVTDNGAEILQTLHSDPGLAVGFDSFGGVDYEGTIFVNTKIDDDYVGF 656
DP+G SQ +PNW V G E++QT++ DPGLAVG+D F VD+ GT F+NT+ DDDY GF
Sbjct: 966 DPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDDDYAGF 1025
Query: 657 IFGYQSNKRFYVVMWKKDKQTYWQKTPFRAVAENGIQLKLVNSKTGPGKILRNALWNTNS 716
+FGYQS+ RFYVVMWK+ Q+YW P RA +G+ +K+VNS TGPG+ LRNALW+T +
Sbjct: 1026 VFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNALWHTGN 1085
Query: 717 TPDQVTLLWKDPRNVGWREQTAYRWKLLHRPKIGLIRLKMYENNRLVADSGNTYDFTLKG 776
TP QV LW DPR++GW++ TAYRW+L HRPK G IR+ MYE +++ADSG YD T G
Sbjct: 1086 TPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYDKTYAG 1145
Query: 777 GRLGVFCFSQEMIIWSNLLYKC 798
GRLG+F FSQEM+ +S+L Y+C
Sbjct: 1146 GRLGLFVFSQEMVFFSDLKYEC 1167
Score = 81.8 bits (193), Expect = 9e-15
Identities = 52/161 (32%), Positives = 73/161 (45%), Gaps = 27/161 (16%)
Query: 39 SQTSDGQTCRT-ACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRI-SCR--A 94
+Q + Q C C +NPCF G V C PDG ++CG CP G+ GNG++C + C+
Sbjct: 538 NQICNKQDCPIDGCLSNPCFAG-VKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVP 596
Query: 95 NTCFQGVS---CEETQYGPKCGSCPTGYVGD---GRQCQH------VCDAQKP------- 135
+ CF CE T G C CP + G G+ +H VC + P
Sbjct: 597 DACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHD 656
Query: 136 CGRERRC--MPKSTSPYYECEGCPSGYQWNGYTCVDMDECD 174
C + +C + + P Y CE C GY NG C + + D
Sbjct: 657 CNKNAKCNYLGHYSDPMYRCE-CKPGYAGNGIICGEDTDLD 696
Score = 35.9 bits (79), Expect = 0.57
Identities = 28/89 (31%), Positives = 37/89 (41%), Gaps = 10/89 (11%)
Query: 23 RCVDTDQGFRCERCP----GSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGK-CP 77
RC +TD G+ C CP GSQ GQ A + R PC DG + C K
Sbjct: 607 RCENTDPGYNCLPCPPRFTGSQPF-GQGVEHATANKQVCKPRNPC---TDGTHDCNKNAK 662
Query: 78 SGFHGNGVE-CYRISCRANTCFQGVSCEE 105
+ G+ + YR C+ G+ C E
Sbjct: 663 CNYLGHYSDPMYRCECKPGYAGNGIICGE 691
>X04665-1|CAA28370.1| 1170|Homo sapiens protein ( Human mRNA for
thrombospondin. ).
Length = 1170
Score = 481 bits (1187), Expect = e-135
Identities = 231/502 (46%), Positives = 290/502 (57%), Gaps = 12/502 (2%)
Query: 300 KCVCNTGWTGNGTVCGLDRDLDGHPDEQLPC--NEP-RCKKDNCPDVSNSGQEXXXXXXX 356
+C C G+ GNG +CG D DLDG P+E L C N CKKDNCP++ NSGQE
Sbjct: 675 RCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPNLPNSGQEDYDKDGI 734
Query: 357 XXXXXXXXXXXXIPNFPDNCPLTPNPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXX 416
IP+ DNCP NP Q D D D+ G+ CDNCP ++NP Q
Sbjct: 735 GDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDR---DDVGDRCDNCPYNHNPDQADTDNN 791
Query: 417 XXXXXXXXXXXXXXIPNQVDNCPRKYNPQQDDMDSDGVGDVCDNCPRVRNTNQEDTDKDN 476
I N+ DNC YN Q D D DGVGD CDNCP N +Q D+D D
Sbjct: 792 GEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDR 851
Query: 477 VGDACXXXXXXXXXXXXXXXXNCPLIPNSXXXXXXXXXXXXXXXXXXXXXXXXXXXXNCQ 536
+GD C NCP +PN+ NC+
Sbjct: 852 IGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPDDKDNCR 911
Query: 537 IVPNRDQKDSDNDGIGDACDNDIDGDRVINELDNCPTIRRYFERTSGTLMRCRQFTTVRL 596
+VPN DQKDSD DG GDAC +D D D V + D CP E + R+F + L
Sbjct: 912 LVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICP------ENVDISETDFRRFQMIPL 965
Query: 597 DPEGESQQEPNWRVTDNGAEILQTLHSDPGLAVGFDSFGGVDYEGTIFVNTKIDDDYVGF 656
DP+G SQ +PNW V G E++QT++ DPGLAVG+D F VD+ GT F+NT+ DDDY GF
Sbjct: 966 DPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDDDYAGF 1025
Query: 657 IFGYQSNKRFYVVMWKKDKQTYWQKTPFRAVAENGIQLKLVNSKTGPGKILRNALWNTNS 716
+FGYQS+ RFYVVMWK+ Q+YW P RA +G+ +K+VNS TGPG+ LRNALW+T +
Sbjct: 1026 VFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNALWHTGN 1085
Query: 717 TPDQVTLLWKDPRNVGWREQTAYRWKLLHRPKIGLIRLKMYENNRLVADSGNTYDFTLKG 776
TP QV LW DPR++GW++ TAYRW+L HRPK G IR+ MYE +++ADSG YD T G
Sbjct: 1086 TPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYDKTYAG 1145
Query: 777 GRLGVFCFSQEMIIWSNLLYKC 798
GRLG+F FSQEM+ +S+L Y+C
Sbjct: 1146 GRLGLFVFSQEMVFFSDLKYEC 1167
Score = 81.8 bits (193), Expect = 9e-15
Identities = 52/161 (32%), Positives = 73/161 (45%), Gaps = 27/161 (16%)
Query: 39 SQTSDGQTCRT-ACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRI-SCR--A 94
+Q + Q C C +NPCF G V C PDG ++CG CP G+ GNG++C + C+
Sbjct: 538 NQICNKQDCPIDGCLSNPCFAG-VKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVP 596
Query: 95 NTCFQGVS---CEETQYGPKCGSCPTGYVGD---GRQCQH------VCDAQKP------- 135
+ CF CE T G C CP + G G+ +H VC + P
Sbjct: 597 DACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHD 656
Query: 136 CGRERRC--MPKSTSPYYECEGCPSGYQWNGYTCVDMDECD 174
C + +C + + P Y CE C GY NG C + + D
Sbjct: 657 CNKNAKCNYLGHYSDPMYRCE-CKPGYAGNGIICGEDTDLD 696
Score = 35.9 bits (79), Expect = 0.57
Identities = 28/89 (31%), Positives = 37/89 (41%), Gaps = 10/89 (11%)
Query: 23 RCVDTDQGFRCERCP----GSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGK-CP 77
RC +TD G+ C CP GSQ GQ A + R PC DG + C K
Sbjct: 607 RCENTDPGYNCLPCPPRFTGSQPF-GQGVEHATANKQVCKPRNPC---TDGTHDCNKNAK 662
Query: 78 SGFHGNGVE-CYRISCRANTCFQGVSCEE 105
+ G+ + YR C+ G+ C E
Sbjct: 663 CNYLGHYSDPMYRCECKPGYAGNGIICGE 691
>AB209912-1|BAD93149.1| 1225|Homo sapiens thrombospondin 1 precursor
variant protein.
Length = 1225
Score = 481 bits (1186), Expect = e-135
Identities = 231/502 (46%), Positives = 289/502 (57%), Gaps = 12/502 (2%)
Query: 300 KCVCNTGWTGNGTVCGLDRDLDGHPDEQLPC--NEP-RCKKDNCPDVSNSGQEXXXXXXX 356
+C C G+ GNG +CG D DLDG P E L C N CKKDNCP++ NSGQE
Sbjct: 730 RCECKPGYAGNGIICGEDTDLDGWPSENLVCVANATYHCKKDNCPNLPNSGQEDYDKDGI 789
Query: 357 XXXXXXXXXXXXIPNFPDNCPLTPNPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXX 416
IP+ DNCP NP Q D D D+ G+ CDNCP ++NP Q
Sbjct: 790 GDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDR---DDVGDRCDNCPYNHNPDQADTDNN 846
Query: 417 XXXXXXXXXXXXXXIPNQVDNCPRKYNPQQDDMDSDGVGDVCDNCPRVRNTNQEDTDKDN 476
I N+ DNC YN Q D D DGVGD CDNCP N +Q D+D D
Sbjct: 847 GEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDR 906
Query: 477 VGDACXXXXXXXXXXXXXXXXNCPLIPNSXXXXXXXXXXXXXXXXXXXXXXXXXXXXNCQ 536
+GD C NCP +PN+ NC+
Sbjct: 907 IGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPDDKDNCR 966
Query: 537 IVPNRDQKDSDNDGIGDACDNDIDGDRVINELDNCPTIRRYFERTSGTLMRCRQFTTVRL 596
+VPN DQKDSD DG GDAC +D D D V + D CP E + R+F + L
Sbjct: 967 LVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICP------ENVDISETDFRRFQMIPL 1020
Query: 597 DPEGESQQEPNWRVTDNGAEILQTLHSDPGLAVGFDSFGGVDYEGTIFVNTKIDDDYVGF 656
DP+G SQ +PNW V G E++QT++ DPGLAVG+D F VD+ GT F+NT+ DDDY GF
Sbjct: 1021 DPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDDDYAGF 1080
Query: 657 IFGYQSNKRFYVVMWKKDKQTYWQKTPFRAVAENGIQLKLVNSKTGPGKILRNALWNTNS 716
+FGYQS+ RFYVVMWK+ Q+YW P RA +G+ +K+VNS TGPG+ LRNALW+T +
Sbjct: 1081 VFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNALWHTGN 1140
Query: 717 TPDQVTLLWKDPRNVGWREQTAYRWKLLHRPKIGLIRLKMYENNRLVADSGNTYDFTLKG 776
TP QV LW DPR++GW++ TAYRW+L HRPK G IR+ MYE +++ADSG YD T G
Sbjct: 1141 TPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYDKTYAG 1200
Query: 777 GRLGVFCFSQEMIIWSNLLYKC 798
GRLG+F FSQEM+ +S+L Y+C
Sbjct: 1201 GRLGLFVFSQEMVFFSDLKYEC 1222
Score = 82.6 bits (195), Expect = 5e-15
Identities = 56/174 (32%), Positives = 79/174 (45%), Gaps = 28/174 (16%)
Query: 39 SQTSDGQTCRT-ACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRI-SCR--A 94
+Q + Q C C +NPCF G V C PDG ++CG CP G+ GNG++C + C+
Sbjct: 593 NQICNKQDCPIDGCLSNPCFAG-VKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVP 651
Query: 95 NTCFQGVS---CEETQYGPKCGSCPTGYVGD---GRQCQH------VCDAQKP------- 135
+ CF CE T G C CP + G G+ +H VC + P
Sbjct: 652 DACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHD 711
Query: 136 CGRERRC--MPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRN 187
C + +C + + P Y CE C GY NG C + + D P ++LV N
Sbjct: 712 CNKNAKCNYLGHYSDPMYRCE-CKPGYAGNGIICGEDTDLD-GWPSENLVCVAN 763
Score = 35.9 bits (79), Expect = 0.57
Identities = 28/89 (31%), Positives = 37/89 (41%), Gaps = 10/89 (11%)
Query: 23 RCVDTDQGFRCERCP----GSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGK-CP 77
RC +TD G+ C CP GSQ GQ A + R PC DG + C K
Sbjct: 662 RCENTDPGYNCLPCPPRFTGSQPF-GQGVEHATANKQVCKPRNPC---TDGTHDCNKNAK 717
Query: 78 SGFHGNGVE-CYRISCRANTCFQGVSCEE 105
+ G+ + YR C+ G+ C E
Sbjct: 718 CNYLGHYSDPMYRCECKPGYAGNGIICGE 746
>L12350-1|AAA03703.1| 1172|Homo sapiens thrombospondin 2 protein.
Length = 1172
Score = 464 bits (1144), Expect = e-130
Identities = 251/605 (41%), Positives = 322/605 (53%), Gaps = 40/605 (6%)
Query: 218 HCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVN--------- 268
HC D+DECA P +C +T + P + Q + C+PC Y N
Sbjct: 587 HCEDLDECA----LVPD--ICFSTSKVPR--CVNTQPGFHCLPCPPRYRGNQPVGVGLEA 638
Query: 269 --TTRPCFDPDSLVKRCDPSYCRRFNAVCGF-GQ------KCVCNTGWTGNGTVCGLDRD 319
T + +P++ K D ++ +A C + G KC C TG+ G+G +CG D D
Sbjct: 639 AKTEKQVCEPENPCK--DKTHNCHKHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSD 696
Query: 320 LDGHPDEQLPCNEP---RCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDNC 376
LDG P+ L C C KDNCP + NSGQE + + DNC
Sbjct: 697 LDGWPNLNLVCATNATYHCIKDNCPHLPNSGQEDFDKDGIGDACDDDDDNDGVTDEKDNC 756
Query: 377 PLTPNPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXXXXXXXXIPNQVD 436
L NP Q D D+ DE G+ CDNCP +NP Q + N+ D
Sbjct: 757 QLLFNPRQADYDK---DEVGDRCDNCPYVHNPAQIDTDNNGEGDACSVDIDGDDVFNERD 813
Query: 437 NCPRKYNPQQDDMDSDGVGDVCDNCPRVRNTNQEDTDKDNVGDACXXXXXXXXXXXXXXX 496
NCP YN Q D D DGVGD CDNCP V N +Q D D D VGD C
Sbjct: 814 NCPYVYNTDQRDTDGDGVGDHCDNCPLVHNPDQTDVDNDLVGDQCDNNEDIDDDGHQNNQ 873
Query: 497 XNCPLIPNSXXXXXXXXXXXXXXXXXXXXXXXXXXXXNCQIVPNRDQKDSDNDGIGDACD 556
NCP I N+ NC++V N DQ+D D DG GD C
Sbjct: 874 DNCPYISNANQADHDRDGQGDACDPDDDNDGVPDDRDNCRLVFNPDQEDLDGDGRGDICK 933
Query: 557 NDIDGDRVINELDNCPTIRRYFERTSGTLMRCRQFTTVRLDPEGESQQEPNWRVTDNGAE 616
+D D D + + D CP E + + R F V LDP+G +Q +PNW + G E
Sbjct: 934 DDFDNDNIPDIDDVCP------ENNAISETDFRNFQMVPLDPKGTTQIDPNWVIRHQGKE 987
Query: 617 ILQTLHSDPGLAVGFDSFGGVDYEGTIFVNTKIDDDYVGFIFGYQSNKRFYVVMWKKDKQ 676
++QT +SDPG+AVGFD FG VD+ GT +VNT DDDY GF+FGYQS+ RFYVVMWK+ Q
Sbjct: 988 LVQTANSDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQ 1047
Query: 677 TYWQKTPFRAVAENGIQLKLVNSKTGPGKILRNALWNTNSTPDQVTLLWKDPRNVGWREQ 736
TYW+ P RA +G+ LK+VNS TG G+ LRNALW+T +TP QV LW DPRN+GW++
Sbjct: 1048 TYWEDQPTRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTPGQVRTLWHDPRNIGWKDY 1107
Query: 737 TAYRWKLLHRPKIGLIRLKMYENNRLVADSGNTYDFTLKGGRLGVFCFSQEMIIWSNLLY 796
TAYRW L HRPK G IR+ ++E +++ADSG YD T GGRLG+F FSQEM+ +S+L Y
Sbjct: 1108 TAYRWHLTHRPKTGYIRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKY 1167
Query: 797 KCNAI 801
+C I
Sbjct: 1168 ECRDI 1172
Score = 72.1 bits (169), Expect = 7e-12
Identities = 49/148 (33%), Positives = 65/148 (43%), Gaps = 26/148 (17%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRI-SCR--ANTCFQGVS---CE 104
C +NPCF G C PDG + CG CP GF GNG C + C + CF C
Sbjct: 553 CLSNPCFPG-AQCSSFPDGSWSCGFCPVGFLGNGTHCEDLDECALVPDICFSTSKVPRCV 611
Query: 105 ETQYGPKCGSCPTGY-----VGDGRQC----QHVCDAQKPC-GRERRC--------MPKS 146
TQ G C CP Y VG G + + VC+ + PC + C +
Sbjct: 612 NTQPGFHCLPCPPRYRGNQPVGVGLEAAKTEKQVCEPENPCKDKTHNCHKHAECIYLGHF 671
Query: 147 TSPYYECEGCPSGYQWNGYTCVDMDECD 174
+ P Y+CE C +GY +G C + + D
Sbjct: 672 SDPMYKCE-CQTGYAGDGLICGEDSDLD 698
Score = 50.8 bits (116), Expect = 2e-05
Identities = 41/148 (27%), Positives = 58/148 (39%), Gaps = 26/148 (17%)
Query: 48 RTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQ 107
R S P +GG+ D+ + R C K G C +N CF G C
Sbjct: 519 RVCNSPEPQYGGKACVGDVQE-RQMCNKRSCPVDG---------CLSNPCFPGAQCSSFP 568
Query: 108 YGP-KCGSCPTGYVGDGRQCQH------VCDAQKPCGRERRCMPKSTSPYYECEGCPSGY 160
G CG CP G++G+G C+ V D + RC+ +T P + C CP Y
Sbjct: 569 DGSWSCGFCPVGFLGNGTHCEDLDECALVPDICFSTSKVPRCV--NTQPGFHCLPCPPRY 626
Query: 161 QWNGYTCVDMDE-------CDLIRPCDD 181
+ N V ++ C+ PC D
Sbjct: 627 RGNQPVGVGLEAAKTEKQVCEPENPCKD 654
>BX322234-1|CAI23645.1| 1172|Homo sapiens thrombospondin 2 protein.
Length = 1172
Score = 464 bits (1144), Expect = e-130
Identities = 251/605 (41%), Positives = 322/605 (53%), Gaps = 40/605 (6%)
Query: 218 HCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVN--------- 268
HC D+DECA P +C +T + P + Q + C+PC Y N
Sbjct: 587 HCEDLDECA----LVPD--ICFSTSKVPR--CVNTQPGFHCLPCPPRYRGNQPVGVGLEA 638
Query: 269 --TTRPCFDPDSLVKRCDPSYCRRFNAVCGF-GQ------KCVCNTGWTGNGTVCGLDRD 319
T + +P++ K D ++ +A C + G KC C TG+ G+G +CG D D
Sbjct: 639 AKTEKQVCEPENPCK--DKTHNCHKHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSD 696
Query: 320 LDGHPDEQLPCNEP---RCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDNC 376
LDG P+ L C C KDNCP + NSGQE + + DNC
Sbjct: 697 LDGWPNLNLVCATNATYHCIKDNCPHLPNSGQEDFDKDGIGDACDDDDDNDGVTDEKDNC 756
Query: 377 PLTPNPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXXXXXXXXIPNQVD 436
L NP Q D D+ DE G+ CDNCP +NP Q + N+ D
Sbjct: 757 QLLFNPRQADYDK---DEVGDRCDNCPYVHNPAQIDTDNNGEGDACSVDIDGDDVFNERD 813
Query: 437 NCPRKYNPQQDDMDSDGVGDVCDNCPRVRNTNQEDTDKDNVGDACXXXXXXXXXXXXXXX 496
NCP YN Q D D DGVGD CDNCP V N +Q D D D VGD C
Sbjct: 814 NCPYVYNTDQRDTDGDGVGDHCDNCPLVHNPDQTDVDNDLVGDQCDNNEDIDDDGHQNNQ 873
Query: 497 XNCPLIPNSXXXXXXXXXXXXXXXXXXXXXXXXXXXXNCQIVPNRDQKDSDNDGIGDACD 556
NCP I N+ NC++V N DQ+D D DG GD C
Sbjct: 874 DNCPYISNANQADHDRDGQGDACDPDDDNDGVPDDRDNCRLVFNPDQEDLDGDGRGDICK 933
Query: 557 NDIDGDRVINELDNCPTIRRYFERTSGTLMRCRQFTTVRLDPEGESQQEPNWRVTDNGAE 616
+D D D + + D CP E + + R F V LDP+G +Q +PNW + G E
Sbjct: 934 DDFDNDNIPDIDDVCP------ENNAISETDFRNFQMVPLDPKGTTQIDPNWVIRHQGKE 987
Query: 617 ILQTLHSDPGLAVGFDSFGGVDYEGTIFVNTKIDDDYVGFIFGYQSNKRFYVVMWKKDKQ 676
++QT +SDPG+AVGFD FG VD+ GT +VNT DDDY GF+FGYQS+ RFYVVMWK+ Q
Sbjct: 988 LVQTANSDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQ 1047
Query: 677 TYWQKTPFRAVAENGIQLKLVNSKTGPGKILRNALWNTNSTPDQVTLLWKDPRNVGWREQ 736
TYW+ P RA +G+ LK+VNS TG G+ LRNALW+T +TP QV LW DPRN+GW++
Sbjct: 1048 TYWEDQPTRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTPGQVRTLWHDPRNIGWKDY 1107
Query: 737 TAYRWKLLHRPKIGLIRLKMYENNRLVADSGNTYDFTLKGGRLGVFCFSQEMIIWSNLLY 796
TAYRW L HRPK G IR+ ++E +++ADSG YD T GGRLG+F FSQEM+ +S+L Y
Sbjct: 1108 TAYRWHLTHRPKTGYIRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKY 1167
Query: 797 KCNAI 801
+C I
Sbjct: 1168 ECRDI 1172
Score = 73.3 bits (172), Expect = 3e-12
Identities = 49/148 (33%), Positives = 65/148 (43%), Gaps = 26/148 (17%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRI-SCR--ANTCFQGVS---CE 104
C +NPCF G C PDG + CG CP GF GNG C + C + CF C
Sbjct: 553 CLSNPCFPG-AQCSSFPDGSWSCGSCPVGFLGNGTHCEDLDECALVPDICFSTSKVPRCV 611
Query: 105 ETQYGPKCGSCPTGY-----VGDGRQC----QHVCDAQKPC-GRERRC--------MPKS 146
TQ G C CP Y VG G + + VC+ + PC + C +
Sbjct: 612 NTQPGFHCLPCPPRYRGNQPVGVGLEAAKTEKQVCEPENPCKDKTHNCHKHAECIYLGHF 671
Query: 147 TSPYYECEGCPSGYQWNGYTCVDMDECD 174
+ P Y+CE C +GY +G C + + D
Sbjct: 672 SDPMYKCE-CQTGYAGDGLICGEDSDLD 698
Score = 53.2 bits (122), Expect = 4e-06
Identities = 42/148 (28%), Positives = 59/148 (39%), Gaps = 26/148 (17%)
Query: 48 RTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQ 107
R S P +GG+ D+ + R C K G C +N CF G C
Sbjct: 519 RVCNSPEPQYGGKACVGDVQE-RQMCNKRSCPVDG---------CLSNPCFPGAQCSSFP 568
Query: 108 YGP-KCGSCPTGYVGDGRQCQH------VCDAQKPCGRERRCMPKSTSPYYECEGCPSGY 160
G CGSCP G++G+G C+ V D + RC+ +T P + C CP Y
Sbjct: 569 DGSWSCGSCPVGFLGNGTHCEDLDECALVPDICFSTSKVPRCV--NTQPGFHCLPCPPRY 626
Query: 161 QWNGYTCVDMDE-------CDLIRPCDD 181
+ N V ++ C+ PC D
Sbjct: 627 RGNQPVGVGLEAAKTEKQVCEPENPCKD 654
>BX641023-1|CAE46014.1| 430|Homo sapiens hypothetical protein
protein.
Length = 430
Score = 409 bits (1008), Expect = e-113
Identities = 199/428 (46%), Positives = 248/428 (57%), Gaps = 9/428 (2%)
Query: 374 DNCPLTPNPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXXXXXXXXIPN 433
DNC L NP Q D D+ DE G+ CDNCP +NP Q + N
Sbjct: 12 DNCQLLFNPRQADYDK---DEVGDRCDNCPYVHNPAQIDTDNNGEGDACSVDIDGDDVFN 68
Query: 434 QVDNCPRKYNPQQDDMDSDGVGDVCDNCPRVRNTNQEDTDKDNVGDACXXXXXXXXXXXX 493
+ DNCP YN Q D D DGVGD CDNCP V N +Q D D D VGD C
Sbjct: 69 ERDNCPYVYNTDQRDTDGDGVGDHCDNCPLVHNPDQTDVDNDLVGDQCDNNEDIDDDGHQ 128
Query: 494 XXXXNCPLIPNSXXXXXXXXXXXXXXXXXXXXXXXXXXXXNCQIVPNRDQKDSDNDGIGD 553
NCP I N+ NC++V N DQ+D D DG GD
Sbjct: 129 NNQDNCPYISNANQADHDRDGQGDACDPDDDNDGVPDDRDNCRLVFNPDQEDLDGDGRGD 188
Query: 554 ACDNDIDGDRVINELDNCPTIRRYFERTSGTLMRCRQFTTVRLDPEGESQQEPNWRVTDN 613
C +D D D + + D CP E + + R F V LDP+G +Q +PNW +
Sbjct: 189 ICKDDFDNDNIPDIDDVCP------ENNAISETDFRNFQMVPLDPKGTTQIDPNWVIRHQ 242
Query: 614 GAEILQTLHSDPGLAVGFDSFGGVDYEGTIFVNTKIDDDYVGFIFGYQSNKRFYVVMWKK 673
G E++QT +SDPG+AVGFD FG VD+ GT +VNT DDDY GF+FGYQS+ RFYVVMWK+
Sbjct: 243 GKELVQTANSDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQ 302
Query: 674 DKQTYWQKTPFRAVAENGIQLKLVNSKTGPGKILRNALWNTNSTPDQVTLLWKDPRNVGW 733
QTYW+ P RA +G+ LK+VNS TG G+ LRNALW+T +TP QV LW DPRN+GW
Sbjct: 303 VTQTYWEDQPTRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTPGQVRTLWHDPRNIGW 362
Query: 734 REQTAYRWKLLHRPKIGLIRLKMYENNRLVADSGNTYDFTLKGGRLGVFCFSQEMIIWSN 793
++ TAYRW L HRPK G IR+ ++E +++ADSG YD T GGRLG+F FSQEM+ +S+
Sbjct: 363 KDYTAYRWHLTHRPKTGYIRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMVYFSD 422
Query: 794 LLYKCNAI 801
L Y+C I
Sbjct: 423 LKYECRDI 430
Score = 93.9 bits (223), Expect = 2e-18
Identities = 56/146 (38%), Positives = 66/146 (45%), Gaps = 17/146 (11%)
Query: 431 IPNQVDNCPRKYNPQQDDMDSDGVGDVCDNCPRVRNTNQEDTDKDNVGDACXXXXXXXXX 490
+ ++ DNC +NP+Q D D D VGD CDNCP V N Q DTD + GDAC
Sbjct: 7 VTDEKDNCQLLFNPRQADYDKDEVGDRCDNCPYVHNPAQIDTDNNGEGDAC--SVDIDGD 64
Query: 491 XXXXXXXNCPLIPNSXXXXXXXXXXXXXXXXXXXXXXXXXXXXNCQIVPNRDQKDSDNDG 550
NCP + N+ NC +V N DQ D DND
Sbjct: 65 DVFNERDNCPYVYNT-------------DQRDTDGDGVGDHCDNCPLVHNPDQTDVDNDL 111
Query: 551 IGDACDN--DIDGDRVINELDNCPTI 574
+GD CDN DID D N DNCP I
Sbjct: 112 VGDQCDNNEDIDDDGHQNNQDNCPYI 137
Score = 74.9 bits (176), Expect = 1e-12
Identities = 56/163 (34%), Positives = 60/163 (36%), Gaps = 20/163 (12%)
Query: 334 RCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDNCPLTPNPDQLDDDENKSD 393
RC DNCP V N Q + N DNCP N DQ D D D
Sbjct: 33 RC--DNCPYVHNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPYVYNTDQRDTD---GD 87
Query: 394 ERGNACDNCPRHYNPRQEXXXXXXXXX--XXXXXXXXXXIPNQVDNCPRKYNPQQDDMDS 451
G+ CDNCP +NP Q N DNCP N Q D D
Sbjct: 88 GVGDHCDNCPLVHNPDQTDVDNDLVGDQCDNNEDIDDDGHQNNQDNCPYISNANQADHDR 147
Query: 452 DGVGDVC-------------DNCPRVRNTNQEDTDKDNVGDAC 481
DG GD C DNC V N +QED D D GD C
Sbjct: 148 DGQGDACDPDDDNDGVPDDRDNCRLVFNPDQEDLDGDGRGDIC 190
Score = 65.3 bits (152), Expect = 8e-10
Identities = 44/133 (33%), Positives = 53/133 (39%), Gaps = 25/133 (18%)
Query: 448 DMDSDGVGDVCDNCPRVRNTNQEDTDKDNVGDACXXXXXXXXXXXXXXXXNCPLIPNSXX 507
D D+DGV D DNC + N Q D DKD VGD C NCP + N
Sbjct: 1 DDDNDGVTDEKDNCQLLFNPRQADYDKDEVGDRC---------------DNCPYVHNPAQ 45
Query: 508 XXXXXXXXXXXXXXXXXXXXXXXXXXNCQIVPNRDQKDSDNDGIGDACDN---------- 557
NC V N DQ+D+D DG+GD CDN
Sbjct: 46 IDTDNNGEGDACSVDIDGDDVFNERDNCPYVYNTDQRDTDGDGVGDHCDNCPLVHNPDQT 105
Query: 558 DIDGDRVINELDN 570
D+D D V ++ DN
Sbjct: 106 DVDNDLVGDQCDN 118
Score = 41.1 bits (92), Expect = 0.015
Identities = 32/107 (29%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 296 GFGQKCVCNTGWTGNGTVCGLDRDLDGHP---DEQLPCNEPRCKKDNCPDVSNSGQEXXX 352
G G C N N +D DL G +E + + + +DNCP +SN+ Q
Sbjct: 88 GVGDHCD-NCPLVHNPDQTDVDNDLVGDQCDNNEDIDDDGHQNNQDNCPYISNANQADHD 146
Query: 353 XXXXXXXXXXXXXXXXIPNFPDNCPLTPNPDQLDDDENKSDERGNAC 399
+P+ DNC L NPDQ D D D RG+ C
Sbjct: 147 RDGQGDACDPDDDNDGVPDDRDNCRLVFNPDQEDLD---GDGRGDIC 190
>AF023268-6|AAC51818.1| 736|Homo sapiens thrombospondin3 protein.
Length = 736
Score = 272 bits (668), Expect = 2e-72
Identities = 170/478 (35%), Positives = 206/478 (43%), Gaps = 37/478 (7%)
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXX 194
PC R CM P Y C CP G Q NG C D++EC PC SC N
Sbjct: 282 PCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCINTMPGFHC 341
Query: 195 XXXXXXXXXSQGWRGTGNERRR---EHCVDVDECADGR-ANCPRGRLCVNTPQYPSNPVS 250
+Q G G + R + C D+DEC DG C +C NT
Sbjct: 342 EACPRGYKGTQV-SGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTV-------- 392
Query: 251 SLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQK----CVCNTG 306
GS+ C PC + N ++ C P S C +A C F + C CN G
Sbjct: 393 ---GSFKCGPCRLGFLGNQSQGCL-PARTCHSPAHSPCH-IHAHCLFERNGAVSCQCNVG 447
Query: 307 WTGNGTVCGLDRDLDGHPDEQLPC--NEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXX 364
W GNG VCG D D+DG+PD+ LPC N CK+DNC NSGQE
Sbjct: 448 WAGNGNVCGTDTDIDGYPDQALPCMDNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDA 507
Query: 365 XXXXIPNFPDNCPLTPNPDQLDDDENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXXX 424
I N DNC L PN DQ + D +D G+ACDNCP N Q+
Sbjct: 508 DGDGIKNVEDNCRLFPNKDQQNSD---TDSFGDACDNCPNVPNNDQKDTDGNGEGDACDN 564
Query: 425 XXXXXXIPNQVDNCPRKYNPQQDDMDSDGVGDVCDNCPRVRNTNQEDTDKDNVGDACXXX 484
IPN +DNCP+ NP Q D D DGVGD CD+CP + N Q D D D VGD C
Sbjct: 565 DVDGDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTN 624
Query: 485 XXXXXXXXXXXXXNCPLIPNSXXXXXXXXXXXXXXXXXXXXXXXXXXX----XNCQIVPN 540
NCP +PNS NC++VPN
Sbjct: 625 EDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPN 684
Query: 541 RDQKDSDNDGIGDACDNDIDGDRVINELDNCPTIRRYFERTSGTLMRCRQFTTVRLDP 598
+QKDSD +G+GD C++D D D V++ LD CP E TL R + TV LDP
Sbjct: 685 PNQKDSDGNGVGDVCEDDFDNDAVVDPLDVCP------ESAEVTLTDFRAYQTVVLDP 736
Score = 97.9 bits (233), Expect = 1e-19
Identities = 125/461 (27%), Positives = 162/461 (35%), Gaps = 82/461 (17%)
Query: 48 RTACSANPCFGGRVPCQDLPD-GRYQCGKCPSGFHGNGVECYRIS--CRANTCFQGVSCE 104
R+ CS NPCF G V C ++ + Y+CG CP G GNG C I+ A+ CF G SC
Sbjct: 275 RSHCSPNPCFRG-VDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCI 333
Query: 105 ETQYGPKCGSCPTGYVGD---------GRQCQHVCDAQKPC--GRERRCMPKS----TSP 149
T G C +CP GY G R + VC+ C G C P S T
Sbjct: 334 NTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVG 393
Query: 150 YYECEGCPSGYQWN-GYTCVDMDEC--DLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQG 206
++C C G+ N C+ C PC C E + G
Sbjct: 394 SFKCGPCRLGFLGNQSQGCLPARTCHSPAHSPCHIHAHCLFER------NGAVSCQCNVG 447
Query: 207 WRGTGNERRREHCVD--VDE---CADGRANCPRGRLCVNTPQYPSNPV-SSLQGSYICVP 260
W G GN + +D D+ C D +C + C+ TP + G
Sbjct: 448 WAGNGNVCGTDTDIDGYPDQALPCMDNNKHCKQDN-CLLTPNSGQEDADNDGVGDQCDDD 506
Query: 261 CGGHYYVNTTRPC-FDPDSLVKRCDP----SYCRRFNAVCGFGQKCVCNTGWTGNGTVCG 315
G N C P+ + D C V QK +T G G C
Sbjct: 507 ADGDGIKNVEDNCRLFPNKDQQNSDTDSFGDACDNCPNVPNNDQK---DTDGNGEGDACD 563
Query: 316 LDRDLDGHPDEQLPCNEPRCKKDNCPDVSNSGQEXXXXXXXXXXXXXXXXXXXIPNFPDN 375
D D DG P+ DNCP V N Q + + D+
Sbjct: 564 NDVDGDGIPN----------GLDNCPKVPNPLQ-------------TDRDEDGVGDACDS 600
Query: 376 CPLTPNPDQLDDD------------ENKSDERGNACDNCPRHYNPRQEXXXXXXXXXXXX 423
CP NP Q D D ++ D + DNCP+ N Q
Sbjct: 601 CPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECD 660
Query: 424 XXXXXXXIPNQV----DNCPRKYNPQQDDMDSDGVGDVCDN 460
IP+ V DNC NP Q D D +GVGDVC++
Sbjct: 661 GDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCED 701
Score = 64.9 bits (151), Expect = 1e-09
Identities = 101/406 (24%), Positives = 142/406 (34%), Gaps = 54/406 (13%)
Query: 30 GFRCERCPGSQTSDGQTCR--TACS-ANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN--- 83
G+RC CP +G C C+ A+PCF G +P + C CP G+ G
Sbjct: 297 GYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCINTMPG--FHCEACPRGYKGTQVS 354
Query: 84 --GVECYRIS---CR-ANTCFQGVS--------CEETQYGPKCGSCPTGYVGDGRQ-C-- 126
G++ R S C + C G + C T KCG C G++G+ Q C
Sbjct: 355 GVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLP 414
Query: 127 QHVC--DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC---VDMDEC-DLIRPC- 179
C A PC C+ + C+ C G+ NG C D+D D PC
Sbjct: 415 ARTCHSPAHSPCHIHAHCLFERNGA-VSCQ-CNVGWAGNGNVCGTDTDIDGYPDQALPCM 472
Query: 180 DDLVSCRNEEXXXXXXXXXXXXXX-------SQGWRGTGNERRREHC-VDVDECADGRAN 231
D+ C+ + G G + ++C + ++
Sbjct: 473 DNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSDT 532
Query: 232 CPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRF 291
G C N P P+N G+ C V+ D+ K +P R
Sbjct: 533 DSFGDACDNCPNVPNNDQKDTDGNGEGDACDND--VDGDGIPNGLDNCPKVPNPLQTDRD 590
Query: 292 NAVCGFGQKCVCNTGWTGNGTVCGLDRDLDG---HPDEQLPCNEPRCKKDNCPDVSNSGQ 348
G G C + N T D DL G +E + + KDNCP + NS Q
Sbjct: 591 ED--GVGDAC-DSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQ 647
Query: 349 EXXXXXXXXXXXXXXXXXXXIPNF----PDNCPLTPNPDQLDDDEN 390
IP++ PDNC L PNP+Q D D N
Sbjct: 648 LDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGN 693
>M99425-1|AAB59366.1| 143|Homo sapiens thrombospondin protein.
Length = 143
Score = 195 bits (476), Expect = 4e-49
Identities = 83/140 (59%), Positives = 107/140 (76%)
Query: 659 GYQSNKRFYVVMWKKDKQTYWQKTPFRAVAENGIQLKLVNSKTGPGKILRNALWNTNSTP 718
GYQS+ RFYVVMWK+ Q+YW P RA +G+ +K+VNS TGPG+ LRNALW+T +TP
Sbjct: 1 GYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNALWHTGNTP 60
Query: 719 DQVTLLWKDPRNVGWREQTAYRWKLLHRPKIGLIRLKMYENNRLVADSGNTYDFTLKGGR 778
QV LW DPR++GW++ TAYRW+L HRPK G IR+ MYE +++ADSG YD T GGR
Sbjct: 61 GQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYDKTYAGGR 120
Query: 779 LGVFCFSQEMIIWSNLLYKC 798
LG+F FSQEM+ +S+L Y+C
Sbjct: 121 LGLFVFSQEMVFFSDLKYEC 140
>AK027344-1|BAB55049.1| 741|Homo sapiens protein ( Homo sapiens
cDNA FLJ14438 fis, clone HEMBB1000317, weakly similar to
FIBULIN-1, ISOFORM D PRECURSOR. ).
Length = 741
Score = 90.6 bits (215), Expect = 2e-17
Identities = 92/322 (28%), Positives = 130/322 (40%), Gaps = 52/322 (16%)
Query: 29 QGFRCERCPGSQTSD--GQTC--RTACSA-NPCFGGRVPCQDLPDGRYQCGKCPSGFH-- 81
+G R +CP T D G C C+A NPC C + G Y C CP G
Sbjct: 308 KGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS---CHNAM-GTYYCS-CPKGLTIA 362
Query: 82 GNGVECYRIS-CRA--NTCFQGVSCEETQYGPKCG-SCPTGY--VGDGRQCQHVCDAQKP 135
+G C I C +TC G C+ T +C C +G+ DG CQ + + Q+
Sbjct: 363 ADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQES 422
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXX 195
+RC S + C GC GYQ G C+D++EC C C+N
Sbjct: 423 SPCHQRCFNAIGS--FHC-GCEPGYQLKGRKCMDVNECRQ-NVCRPDQHCKNTR-GGYKC 477
Query: 196 XXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGS 255
++ GT C+D+DEC DG C ++C NT +GS
Sbjct: 478 IDLCPNGMTKAENGT--------CIDIDECKDGTHQCRYNQICENT-----------RGS 518
Query: 256 YICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCNTGW--TGNGT 312
Y CV G+ RPC D D C+ + + FG +C+C G+ T NG
Sbjct: 519 YRCVCPRGYRSQGVGRPCMDID----ECENTDACQHECKNTFGSYQCICPPGYQLTHNGK 574
Query: 313 VCGLDRDLDGHPDEQLPCNEPR 334
C +D+D ++ + C R
Sbjct: 575 TC---QDIDECLEQNVHCGPNR 593
Score = 79.8 bits (188), Expect = 4e-14
Identities = 76/261 (29%), Positives = 109/261 (41%), Gaps = 47/261 (18%)
Query: 21 GERCVDTDQGFRCE-RCPGS--QTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCG 74
G+ C +T +RC RC +TSDG +C+ N C PC G + CG
Sbjct: 384 GQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQ---DINECQESS-PCHQRCFNAIGSFHCG 439
Query: 75 KCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYGPKC-GSCPTGYV-GDGRQCQHV-- 129
C G+ G +C ++ CR N C C+ T+ G KC CP G + C +
Sbjct: 440 -CEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDE 498
Query: 130 C-DAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLIRPCDDLVSCR 186
C D C + C ++T Y C CP GY Q G C+D+DEC+ C C+
Sbjct: 499 CKDGTHQCRYNQIC--ENTRGSYRCV-CPRGYRSQGVGRPCMDIDECENTDACQH--ECK 553
Query: 187 NEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPS 246
N G++ T N + C D+DEC + +C R+C N
Sbjct: 554 N-------TFGSYQCICPPGYQLTHNGKT---CQDIDECLEQNVHCGPNRMCFN------ 597
Query: 247 NPVSSLQGSYICV--PCGGHY 265
++GSY C+ PC +Y
Sbjct: 598 -----MRGSYQCIDTPCPPNY 613
>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone RP11-465I11 on chromosome 1. ).
Length = 5635
Score = 87.0 bits (206), Expect = 2e-16
Identities = 90/306 (29%), Positives = 123/306 (40%), Gaps = 47/306 (15%)
Query: 29 QGFRCERCPGSQTSD--GQTC--RTACSA-NPCFGGRVPCQDLPDGRYQCGKCPSGFH-- 81
+G R +CP T D G C C+A NPC C + G Y C CP G
Sbjct: 5085 KGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS---CHNAM-GTYYCS-CPKGLTIA 5139
Query: 82 GNGVECYRIS-CRA--NTCFQGVSCEETQYGPKCG-SCPTGY--VGDGRQCQHVCDAQKP 135
+G C I C +TC G C+ T +C C +G+ DG CQ + + Q+
Sbjct: 5140 ADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQES 5199
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXX 195
+RC S + C GC GYQ G C+D++EC C C+N
Sbjct: 5200 SPCHQRCFNAIGS--FHC-GCEPGYQLKGRKCMDVNECRQ-NVCRPDQHCKNTR-GGYKC 5254
Query: 196 XXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGS 255
++ GT C+D+DEC DG C ++C NT +GS
Sbjct: 5255 IDLCPNGMTKAENGT--------CIDIDECKDGTHQCRYNQICENT-----------RGS 5295
Query: 256 YICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTG--WTGNGTV 313
Y CV G+ RPC D + + P + N F KC+C G G+G
Sbjct: 5296 YRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSF--KCICPPGQHLLGDGKS 5353
Query: 314 C-GLDR 318
C GL+R
Sbjct: 5354 CAGLER 5359
Score = 66.5 bits (155), Expect = 4e-10
Identities = 55/174 (31%), Positives = 79/174 (45%), Gaps = 23/174 (13%)
Query: 21 GERCVDTDQGFRCE-RCPGS--QTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCG 74
G+ C +T +RC RC +TSDG +C+ N C PC G + CG
Sbjct: 5161 GQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQ---DINECQESS-PCHQRCFNAIGSFHCG 5216
Query: 75 KCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYGPKC-GSCPTGYV-GDGRQCQHV-- 129
C G+ G +C ++ CR N C C+ T+ G KC CP G + C +
Sbjct: 5217 -CEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDE 5275
Query: 130 C-DAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLI-RPC 179
C D C + C ++T Y C CP GY Q G C+D++EC+ + +PC
Sbjct: 5276 CKDGTHQCRYNQIC--ENTRGSYRCV-CPRGYRSQGVGRPCMDINECEQVPKPC 5326
Score = 55.2 bits (127), Expect = 9e-07
Identities = 63/250 (25%), Positives = 95/250 (38%), Gaps = 39/250 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCGKCPSGF 80
C +T +RC CP S G R N C PC G ++C CP G
Sbjct: 5289 CENTRGSYRCV-CPRGYRSQG-VGRPCMDINECEQVPKPCAHQCSNTPGSFKC-ICPPGQ 5345
Query: 81 H--GNGVECYRISCRANTCFQGVSCEETQYGPKCGSC-PTGYVGDGRQCQHVCDAQKPCG 137
H G+G C + N Q S ++ P + P + RQ H+ +
Sbjct: 5346 HLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHY---RQYSHLYSSYSEYR 5402
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX 197
R + ++ + CP G + + TCVD+DEC+ C C+N
Sbjct: 5403 NSRTSLSRTRRTIRKT--CPEGSEASHDTCVDIDECENTDACQH--ECKN-------TFG 5451
Query: 198 XXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYI 257
G++ T N + C D+DEC + +C R+C N ++GSY
Sbjct: 5452 SYQCICPPGYQLTHNGKT---CQDIDECLEQNVHCGPNRMCFN-----------MRGSYQ 5497
Query: 258 CV--PCGGHY 265
C+ PC +Y
Sbjct: 5498 CIDTPCPPNY 5507
Score = 38.3 bits (85), Expect = 0.11
Identities = 63/227 (27%), Positives = 85/227 (37%), Gaps = 46/227 (20%)
Query: 109 GPKCGSCPTGYVGD--GRQC--QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW-- 162
G + CP+G+ D G C + C A PC C + YY C CP G
Sbjct: 5086 GDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CH-NAMGTYY-CS-CPKGLTIAA 5140
Query: 163 NGYTCVDMDECDLIR-PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVD 221
+G TC D+DEC L R C C N G+R T + C D
Sbjct: 5141 DGRTCQDIDECALGRHTCHAGQDCDN-----TIGSYRCVVRCGSGFRRTSDGL---SCQD 5192
Query: 222 VDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK 281
++EC + + P + C N GS+ C C Y + R C D + +
Sbjct: 5193 INECQE---SSPCHQRCFNA-----------IGSFHC-GCEPGYQLK-GRKCMDVNECRQ 5236
Query: 282 R-CDP-SYCRRFNAVCGFGQKCV--CNTGWT--GNGTVCGLDRDLDG 322
C P +C+ G KC+ C G T NGT +D DG
Sbjct: 5237 NVCRPDQHCKNTRG----GYKCIDLCPNGMTKAENGTCIDIDECKDG 5279
>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-268N14 on chromosome 1. ).
Length = 5635
Score = 87.0 bits (206), Expect = 2e-16
Identities = 90/306 (29%), Positives = 123/306 (40%), Gaps = 47/306 (15%)
Query: 29 QGFRCERCPGSQTSD--GQTC--RTACSA-NPCFGGRVPCQDLPDGRYQCGKCPSGFH-- 81
+G R +CP T D G C C+A NPC C + G Y C CP G
Sbjct: 5085 KGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS---CHNAM-GTYYCS-CPKGLTIA 5139
Query: 82 GNGVECYRIS-CRA--NTCFQGVSCEETQYGPKCG-SCPTGY--VGDGRQCQHVCDAQKP 135
+G C I C +TC G C+ T +C C +G+ DG CQ + + Q+
Sbjct: 5140 ADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQES 5199
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXX 195
+RC S + C GC GYQ G C+D++EC C C+N
Sbjct: 5200 SPCHQRCFNAIGS--FHC-GCEPGYQLKGRKCMDVNECRQ-NVCRPDQHCKNTR-GGYKC 5254
Query: 196 XXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGS 255
++ GT C+D+DEC DG C ++C NT +GS
Sbjct: 5255 IDLCPNGMTKAENGT--------CIDIDECKDGTHQCRYNQICENT-----------RGS 5295
Query: 256 YICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTG--WTGNGTV 313
Y CV G+ RPC D + + P + N F KC+C G G+G
Sbjct: 5296 YRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSF--KCICPPGQHLLGDGKS 5353
Query: 314 C-GLDR 318
C GL+R
Sbjct: 5354 CAGLER 5359
Score = 66.5 bits (155), Expect = 4e-10
Identities = 55/174 (31%), Positives = 79/174 (45%), Gaps = 23/174 (13%)
Query: 21 GERCVDTDQGFRCE-RCPGS--QTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCG 74
G+ C +T +RC RC +TSDG +C+ N C PC G + CG
Sbjct: 5161 GQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQ---DINECQESS-PCHQRCFNAIGSFHCG 5216
Query: 75 KCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYGPKC-GSCPTGYV-GDGRQCQHV-- 129
C G+ G +C ++ CR N C C+ T+ G KC CP G + C +
Sbjct: 5217 -CEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDE 5275
Query: 130 C-DAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLI-RPC 179
C D C + C ++T Y C CP GY Q G C+D++EC+ + +PC
Sbjct: 5276 CKDGTHQCRYNQIC--ENTRGSYRCV-CPRGYRSQGVGRPCMDINECEQVPKPC 5326
Score = 55.2 bits (127), Expect = 9e-07
Identities = 63/250 (25%), Positives = 95/250 (38%), Gaps = 39/250 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCGKCPSGF 80
C +T +RC CP S G R N C PC G ++C CP G
Sbjct: 5289 CENTRGSYRCV-CPRGYRSQG-VGRPCMDINECEQVPKPCAHQCSNTPGSFKC-ICPPGQ 5345
Query: 81 H--GNGVECYRISCRANTCFQGVSCEETQYGPKCGSC-PTGYVGDGRQCQHVCDAQKPCG 137
H G+G C + N Q S ++ P + P + RQ H+ +
Sbjct: 5346 HLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHY---RQYSHLYSSYSEYR 5402
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX 197
R + ++ + CP G + + TCVD+DEC+ C C+N
Sbjct: 5403 NSRTSLSRTRRTIRKT--CPEGSEASHDTCVDIDECENTDACQH--ECKN-------TFG 5451
Query: 198 XXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYI 257
G++ T N + C D+DEC + +C R+C N ++GSY
Sbjct: 5452 SYQCICPPGYQLTHNGKT---CQDIDECLEQNVHCGPNRMCFN-----------MRGSYQ 5497
Query: 258 CV--PCGGHY 265
C+ PC +Y
Sbjct: 5498 CIDTPCPPNY 5507
Score = 38.3 bits (85), Expect = 0.11
Identities = 63/227 (27%), Positives = 85/227 (37%), Gaps = 46/227 (20%)
Query: 109 GPKCGSCPTGYVGD--GRQC--QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW-- 162
G + CP+G+ D G C + C A PC C + YY C CP G
Sbjct: 5086 GDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CH-NAMGTYY-CS-CPKGLTIAA 5140
Query: 163 NGYTCVDMDECDLIR-PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVD 221
+G TC D+DEC L R C C N G+R T + C D
Sbjct: 5141 DGRTCQDIDECALGRHTCHAGQDCDN-----TIGSYRCVVRCGSGFRRTSDGL---SCQD 5192
Query: 222 VDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK 281
++EC + + P + C N GS+ C C Y + R C D + +
Sbjct: 5193 INECQE---SSPCHQRCFNA-----------IGSFHC-GCEPGYQLK-GRKCMDVNECRQ 5236
Query: 282 R-CDP-SYCRRFNAVCGFGQKCV--CNTGWT--GNGTVCGLDRDLDG 322
C P +C+ G KC+ C G T NGT +D DG
Sbjct: 5237 NVCRPDQHCKNTRG----GYKCIDLCPNGMTKAENGTCIDIDECKDG 5279
>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-77J13 on chromosome 1. ).
Length = 5635
Score = 87.0 bits (206), Expect = 2e-16
Identities = 90/306 (29%), Positives = 123/306 (40%), Gaps = 47/306 (15%)
Query: 29 QGFRCERCPGSQTSD--GQTC--RTACSA-NPCFGGRVPCQDLPDGRYQCGKCPSGFH-- 81
+G R +CP T D G C C+A NPC C + G Y C CP G
Sbjct: 5085 KGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS---CHNAM-GTYYCS-CPKGLTIA 5139
Query: 82 GNGVECYRIS-CRA--NTCFQGVSCEETQYGPKCG-SCPTGY--VGDGRQCQHVCDAQKP 135
+G C I C +TC G C+ T +C C +G+ DG CQ + + Q+
Sbjct: 5140 ADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQES 5199
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXX 195
+RC S + C GC GYQ G C+D++EC C C+N
Sbjct: 5200 SPCHQRCFNAIGS--FHC-GCEPGYQLKGRKCMDVNECRQ-NVCRPDQHCKNTR-GGYKC 5254
Query: 196 XXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGS 255
++ GT C+D+DEC DG C ++C NT +GS
Sbjct: 5255 IDLCPNGMTKAENGT--------CIDIDECKDGTHQCRYNQICENT-----------RGS 5295
Query: 256 YICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTG--WTGNGTV 313
Y CV G+ RPC D + + P + N F KC+C G G+G
Sbjct: 5296 YRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSF--KCICPPGQHLLGDGKS 5353
Query: 314 C-GLDR 318
C GL+R
Sbjct: 5354 CAGLER 5359
Score = 66.5 bits (155), Expect = 4e-10
Identities = 55/174 (31%), Positives = 79/174 (45%), Gaps = 23/174 (13%)
Query: 21 GERCVDTDQGFRCE-RCPGS--QTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCG 74
G+ C +T +RC RC +TSDG +C+ N C PC G + CG
Sbjct: 5161 GQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQ---DINECQESS-PCHQRCFNAIGSFHCG 5216
Query: 75 KCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYGPKC-GSCPTGYV-GDGRQCQHV-- 129
C G+ G +C ++ CR N C C+ T+ G KC CP G + C +
Sbjct: 5217 -CEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDE 5275
Query: 130 C-DAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLI-RPC 179
C D C + C ++T Y C CP GY Q G C+D++EC+ + +PC
Sbjct: 5276 CKDGTHQCRYNQIC--ENTRGSYRCV-CPRGYRSQGVGRPCMDINECEQVPKPC 5326
Score = 55.2 bits (127), Expect = 9e-07
Identities = 63/250 (25%), Positives = 95/250 (38%), Gaps = 39/250 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCGKCPSGF 80
C +T +RC CP S G R N C PC G ++C CP G
Sbjct: 5289 CENTRGSYRCV-CPRGYRSQG-VGRPCMDINECEQVPKPCAHQCSNTPGSFKC-ICPPGQ 5345
Query: 81 H--GNGVECYRISCRANTCFQGVSCEETQYGPKCGSC-PTGYVGDGRQCQHVCDAQKPCG 137
H G+G C + N Q S ++ P + P + RQ H+ +
Sbjct: 5346 HLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHY---RQYSHLYSSYSEYR 5402
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX 197
R + ++ + CP G + + TCVD+DEC+ C C+N
Sbjct: 5403 NSRTSLSRTRRTIRKT--CPEGSEASHDTCVDIDECENTDACQH--ECKN-------TFG 5451
Query: 198 XXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYI 257
G++ T N + C D+DEC + +C R+C N ++GSY
Sbjct: 5452 SYQCICPPGYQLTHNGKT---CQDIDECLEQNVHCGPNRMCFN-----------MRGSYQ 5497
Query: 258 CV--PCGGHY 265
C+ PC +Y
Sbjct: 5498 CIDTPCPPNY 5507
Score = 38.3 bits (85), Expect = 0.11
Identities = 63/227 (27%), Positives = 85/227 (37%), Gaps = 46/227 (20%)
Query: 109 GPKCGSCPTGYVGD--GRQC--QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW-- 162
G + CP+G+ D G C + C A PC C + YY C CP G
Sbjct: 5086 GDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CH-NAMGTYY-CS-CPKGLTIAA 5140
Query: 163 NGYTCVDMDECDLIR-PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVD 221
+G TC D+DEC L R C C N G+R T + C D
Sbjct: 5141 DGRTCQDIDECALGRHTCHAGQDCDN-----TIGSYRCVVRCGSGFRRTSDGL---SCQD 5192
Query: 222 VDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK 281
++EC + + P + C N GS+ C C Y + R C D + +
Sbjct: 5193 INECQE---SSPCHQRCFNA-----------IGSFHC-GCEPGYQLK-GRKCMDVNECRQ 5236
Query: 282 R-CDP-SYCRRFNAVCGFGQKCV--CNTGWT--GNGTVCGLDRDLDG 322
C P +C+ G KC+ C G T NGT +D DG
Sbjct: 5237 NVCRPDQHCKNTRG----GYKCIDLCPNGMTKAENGTCIDIDECKDG 5279
>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-164L12 on chromosome 1. ).
Length = 5635
Score = 87.0 bits (206), Expect = 2e-16
Identities = 90/306 (29%), Positives = 123/306 (40%), Gaps = 47/306 (15%)
Query: 29 QGFRCERCPGSQTSD--GQTC--RTACSA-NPCFGGRVPCQDLPDGRYQCGKCPSGFH-- 81
+G R +CP T D G C C+A NPC C + G Y C CP G
Sbjct: 5085 KGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS---CHNAM-GTYYCS-CPKGLTIA 5139
Query: 82 GNGVECYRIS-CRA--NTCFQGVSCEETQYGPKCG-SCPTGY--VGDGRQCQHVCDAQKP 135
+G C I C +TC G C+ T +C C +G+ DG CQ + + Q+
Sbjct: 5140 ADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQES 5199
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXX 195
+RC S + C GC GYQ G C+D++EC C C+N
Sbjct: 5200 SPCHQRCFNAIGS--FHC-GCEPGYQLKGRKCMDVNECRQ-NVCRPDQHCKNTR-GGYKC 5254
Query: 196 XXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGS 255
++ GT C+D+DEC DG C ++C NT +GS
Sbjct: 5255 IDLCPNGMTKAENGT--------CIDIDECKDGTHQCRYNQICENT-----------RGS 5295
Query: 256 YICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTG--WTGNGTV 313
Y CV G+ RPC D + + P + N F KC+C G G+G
Sbjct: 5296 YRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSF--KCICPPGQHLLGDGKS 5353
Query: 314 C-GLDR 318
C GL+R
Sbjct: 5354 CAGLER 5359
Score = 66.5 bits (155), Expect = 4e-10
Identities = 55/174 (31%), Positives = 79/174 (45%), Gaps = 23/174 (13%)
Query: 21 GERCVDTDQGFRCE-RCPGS--QTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCG 74
G+ C +T +RC RC +TSDG +C+ N C PC G + CG
Sbjct: 5161 GQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQ---DINECQESS-PCHQRCFNAIGSFHCG 5216
Query: 75 KCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYGPKC-GSCPTGYV-GDGRQCQHV-- 129
C G+ G +C ++ CR N C C+ T+ G KC CP G + C +
Sbjct: 5217 -CEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDE 5275
Query: 130 C-DAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLI-RPC 179
C D C + C ++T Y C CP GY Q G C+D++EC+ + +PC
Sbjct: 5276 CKDGTHQCRYNQIC--ENTRGSYRCV-CPRGYRSQGVGRPCMDINECEQVPKPC 5326
Score = 55.2 bits (127), Expect = 9e-07
Identities = 63/250 (25%), Positives = 95/250 (38%), Gaps = 39/250 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCGKCPSGF 80
C +T +RC CP S G R N C PC G ++C CP G
Sbjct: 5289 CENTRGSYRCV-CPRGYRSQG-VGRPCMDINECEQVPKPCAHQCSNTPGSFKC-ICPPGQ 5345
Query: 81 H--GNGVECYRISCRANTCFQGVSCEETQYGPKCGSC-PTGYVGDGRQCQHVCDAQKPCG 137
H G+G C + N Q S ++ P + P + RQ H+ +
Sbjct: 5346 HLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHY---RQYSHLYSSYSEYR 5402
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX 197
R + ++ + CP G + + TCVD+DEC+ C C+N
Sbjct: 5403 NSRTSLSRTRRTIRKT--CPEGSEASHDTCVDIDECENTDACQH--ECKN-------TFG 5451
Query: 198 XXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYI 257
G++ T N + C D+DEC + +C R+C N ++GSY
Sbjct: 5452 SYQCICPPGYQLTHNGKT---CQDIDECLEQNVHCGPNRMCFN-----------MRGSYQ 5497
Query: 258 CV--PCGGHY 265
C+ PC +Y
Sbjct: 5498 CIDTPCPPNY 5507
Score = 38.3 bits (85), Expect = 0.11
Identities = 63/227 (27%), Positives = 85/227 (37%), Gaps = 46/227 (20%)
Query: 109 GPKCGSCPTGYVGD--GRQC--QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW-- 162
G + CP+G+ D G C + C A PC C + YY C CP G
Sbjct: 5086 GDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CH-NAMGTYY-CS-CPKGLTIAA 5140
Query: 163 NGYTCVDMDECDLIR-PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVD 221
+G TC D+DEC L R C C N G+R T + C D
Sbjct: 5141 DGRTCQDIDECALGRHTCHAGQDCDN-----TIGSYRCVVRCGSGFRRTSDGL---SCQD 5192
Query: 222 VDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK 281
++EC + + P + C N GS+ C C Y + R C D + +
Sbjct: 5193 INECQE---SSPCHQRCFNA-----------IGSFHC-GCEPGYQLK-GRKCMDVNECRQ 5236
Query: 282 R-CDP-SYCRRFNAVCGFGQKCV--CNTGWT--GNGTVCGLDRDLDG 322
C P +C+ G KC+ C G T NGT +D DG
Sbjct: 5237 NVCRPDQHCKNTRG----GYKCIDLCPNGMTKAENGTCIDIDECKDG 5279
>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-174L6 on chromosome 1. ).
Length = 5635
Score = 87.0 bits (206), Expect = 2e-16
Identities = 90/306 (29%), Positives = 123/306 (40%), Gaps = 47/306 (15%)
Query: 29 QGFRCERCPGSQTSD--GQTC--RTACSA-NPCFGGRVPCQDLPDGRYQCGKCPSGFH-- 81
+G R +CP T D G C C+A NPC C + G Y C CP G
Sbjct: 5085 KGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS---CHNAM-GTYYCS-CPKGLTIA 5139
Query: 82 GNGVECYRIS-CRA--NTCFQGVSCEETQYGPKCG-SCPTGY--VGDGRQCQHVCDAQKP 135
+G C I C +TC G C+ T +C C +G+ DG CQ + + Q+
Sbjct: 5140 ADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQES 5199
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXX 195
+RC S + C GC GYQ G C+D++EC C C+N
Sbjct: 5200 SPCHQRCFNAIGS--FHC-GCEPGYQLKGRKCMDVNECRQ-NVCRPDQHCKNTR-GGYKC 5254
Query: 196 XXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGS 255
++ GT C+D+DEC DG C ++C NT +GS
Sbjct: 5255 IDLCPNGMTKAENGT--------CIDIDECKDGTHQCRYNQICENT-----------RGS 5295
Query: 256 YICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTG--WTGNGTV 313
Y CV G+ RPC D + + P + N F KC+C G G+G
Sbjct: 5296 YRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSF--KCICPPGQHLLGDGKS 5353
Query: 314 C-GLDR 318
C GL+R
Sbjct: 5354 CAGLER 5359
Score = 66.5 bits (155), Expect = 4e-10
Identities = 55/174 (31%), Positives = 79/174 (45%), Gaps = 23/174 (13%)
Query: 21 GERCVDTDQGFRCE-RCPGS--QTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCG 74
G+ C +T +RC RC +TSDG +C+ N C PC G + CG
Sbjct: 5161 GQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQ---DINECQESS-PCHQRCFNAIGSFHCG 5216
Query: 75 KCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYGPKC-GSCPTGYV-GDGRQCQHV-- 129
C G+ G +C ++ CR N C C+ T+ G KC CP G + C +
Sbjct: 5217 -CEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDE 5275
Query: 130 C-DAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLI-RPC 179
C D C + C ++T Y C CP GY Q G C+D++EC+ + +PC
Sbjct: 5276 CKDGTHQCRYNQIC--ENTRGSYRCV-CPRGYRSQGVGRPCMDINECEQVPKPC 5326
Score = 55.2 bits (127), Expect = 9e-07
Identities = 63/250 (25%), Positives = 95/250 (38%), Gaps = 39/250 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCGKCPSGF 80
C +T +RC CP S G R N C PC G ++C CP G
Sbjct: 5289 CENTRGSYRCV-CPRGYRSQG-VGRPCMDINECEQVPKPCAHQCSNTPGSFKC-ICPPGQ 5345
Query: 81 H--GNGVECYRISCRANTCFQGVSCEETQYGPKCGSC-PTGYVGDGRQCQHVCDAQKPCG 137
H G+G C + N Q S ++ P + P + RQ H+ +
Sbjct: 5346 HLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHY---RQYSHLYSSYSEYR 5402
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX 197
R + ++ + CP G + + TCVD+DEC+ C C+N
Sbjct: 5403 NSRTSLSRTRRTIRKT--CPEGSEASHDTCVDIDECENTDACQH--ECKN-------TFG 5451
Query: 198 XXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYI 257
G++ T N + C D+DEC + +C R+C N ++GSY
Sbjct: 5452 SYQCICPPGYQLTHNGKT---CQDIDECLEQNVHCGPNRMCFN-----------MRGSYQ 5497
Query: 258 CV--PCGGHY 265
C+ PC +Y
Sbjct: 5498 CIDTPCPPNY 5507
Score = 38.3 bits (85), Expect = 0.11
Identities = 63/227 (27%), Positives = 85/227 (37%), Gaps = 46/227 (20%)
Query: 109 GPKCGSCPTGYVGD--GRQC--QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW-- 162
G + CP+G+ D G C + C A PC C + YY C CP G
Sbjct: 5086 GDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CH-NAMGTYY-CS-CPKGLTIAA 5140
Query: 163 NGYTCVDMDECDLIR-PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVD 221
+G TC D+DEC L R C C N G+R T + C D
Sbjct: 5141 DGRTCQDIDECALGRHTCHAGQDCDN-----TIGSYRCVVRCGSGFRRTSDGL---SCQD 5192
Query: 222 VDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK 281
++EC + + P + C N GS+ C C Y + R C D + +
Sbjct: 5193 INECQE---SSPCHQRCFNA-----------IGSFHC-GCEPGYQLK-GRKCMDVNECRQ 5236
Query: 282 R-CDP-SYCRRFNAVCGFGQKCV--CNTGWT--GNGTVCGLDRDLDG 322
C P +C+ G KC+ C G T NGT +D DG
Sbjct: 5237 NVCRPDQHCKNTRG----GYKCIDLCPNGMTKAENGTCIDIDECKDG 5279
>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-153O3 on chromosome 1. ).
Length = 5635
Score = 87.0 bits (206), Expect = 2e-16
Identities = 90/306 (29%), Positives = 123/306 (40%), Gaps = 47/306 (15%)
Query: 29 QGFRCERCPGSQTSD--GQTC--RTACSA-NPCFGGRVPCQDLPDGRYQCGKCPSGFH-- 81
+G R +CP T D G C C+A NPC C + G Y C CP G
Sbjct: 5085 KGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS---CHNAM-GTYYCS-CPKGLTIA 5139
Query: 82 GNGVECYRIS-CRA--NTCFQGVSCEETQYGPKCG-SCPTGY--VGDGRQCQHVCDAQKP 135
+G C I C +TC G C+ T +C C +G+ DG CQ + + Q+
Sbjct: 5140 ADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQES 5199
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXX 195
+RC S + C GC GYQ G C+D++EC C C+N
Sbjct: 5200 SPCHQRCFNAIGS--FHC-GCEPGYQLKGRKCMDVNECRQ-NVCRPDQHCKNTR-GGYKC 5254
Query: 196 XXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGS 255
++ GT C+D+DEC DG C ++C NT +GS
Sbjct: 5255 IDLCPNGMTKAENGT--------CIDIDECKDGTHQCRYNQICENT-----------RGS 5295
Query: 256 YICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTG--WTGNGTV 313
Y CV G+ RPC D + + P + N F KC+C G G+G
Sbjct: 5296 YRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSF--KCICPPGQHLLGDGKS 5353
Query: 314 C-GLDR 318
C GL+R
Sbjct: 5354 CAGLER 5359
Score = 66.5 bits (155), Expect = 4e-10
Identities = 55/174 (31%), Positives = 79/174 (45%), Gaps = 23/174 (13%)
Query: 21 GERCVDTDQGFRCE-RCPGS--QTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCG 74
G+ C +T +RC RC +TSDG +C+ N C PC G + CG
Sbjct: 5161 GQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQ---DINECQESS-PCHQRCFNAIGSFHCG 5216
Query: 75 KCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYGPKC-GSCPTGYV-GDGRQCQHV-- 129
C G+ G +C ++ CR N C C+ T+ G KC CP G + C +
Sbjct: 5217 -CEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDE 5275
Query: 130 C-DAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLI-RPC 179
C D C + C ++T Y C CP GY Q G C+D++EC+ + +PC
Sbjct: 5276 CKDGTHQCRYNQIC--ENTRGSYRCV-CPRGYRSQGVGRPCMDINECEQVPKPC 5326
Score = 55.2 bits (127), Expect = 9e-07
Identities = 63/250 (25%), Positives = 95/250 (38%), Gaps = 39/250 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCGKCPSGF 80
C +T +RC CP S G R N C PC G ++C CP G
Sbjct: 5289 CENTRGSYRCV-CPRGYRSQG-VGRPCMDINECEQVPKPCAHQCSNTPGSFKC-ICPPGQ 5345
Query: 81 H--GNGVECYRISCRANTCFQGVSCEETQYGPKCGSC-PTGYVGDGRQCQHVCDAQKPCG 137
H G+G C + N Q S ++ P + P + RQ H+ +
Sbjct: 5346 HLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHY---RQYSHLYSSYSEYR 5402
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX 197
R + ++ + CP G + + TCVD+DEC+ C C+N
Sbjct: 5403 NSRTSLSRTRRTIRKT--CPEGSEASHDTCVDIDECENTDACQH--ECKN-------TFG 5451
Query: 198 XXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYI 257
G++ T N + C D+DEC + +C R+C N ++GSY
Sbjct: 5452 SYQCICPPGYQLTHNGKT---CQDIDECLEQNVHCGPNRMCFN-----------MRGSYQ 5497
Query: 258 CV--PCGGHY 265
C+ PC +Y
Sbjct: 5498 CIDTPCPPNY 5507
Score = 38.3 bits (85), Expect = 0.11
Identities = 63/227 (27%), Positives = 85/227 (37%), Gaps = 46/227 (20%)
Query: 109 GPKCGSCPTGYVGD--GRQC--QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW-- 162
G + CP+G+ D G C + C A PC C + YY C CP G
Sbjct: 5086 GDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CH-NAMGTYY-CS-CPKGLTIAA 5140
Query: 163 NGYTCVDMDECDLIR-PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVD 221
+G TC D+DEC L R C C N G+R T + C D
Sbjct: 5141 DGRTCQDIDECALGRHTCHAGQDCDN-----TIGSYRCVVRCGSGFRRTSDGL---SCQD 5192
Query: 222 VDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK 281
++EC + + P + C N GS+ C C Y + R C D + +
Sbjct: 5193 INECQE---SSPCHQRCFNA-----------IGSFHC-GCEPGYQLK-GRKCMDVNECRQ 5236
Query: 282 R-CDP-SYCRRFNAVCGFGQKCV--CNTGWT--GNGTVCGLDRDLDG 322
C P +C+ G KC+ C G T NGT +D DG
Sbjct: 5237 NVCRPDQHCKNTRG----GYKCIDLCPNGMTKAENGTCIDIDECKDG 5279
>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
Length = 5635
Score = 87.0 bits (206), Expect = 2e-16
Identities = 90/306 (29%), Positives = 123/306 (40%), Gaps = 47/306 (15%)
Query: 29 QGFRCERCPGSQTSD--GQTC--RTACSA-NPCFGGRVPCQDLPDGRYQCGKCPSGFH-- 81
+G R +CP T D G C C+A NPC C + G Y C CP G
Sbjct: 5085 KGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS---CHNAM-GTYYCS-CPKGLTIA 5139
Query: 82 GNGVECYRIS-CRA--NTCFQGVSCEETQYGPKCG-SCPTGY--VGDGRQCQHVCDAQKP 135
+G C I C +TC G C+ T +C C +G+ DG CQ + + Q+
Sbjct: 5140 ADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQES 5199
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXX 195
+RC S + C GC GYQ G C+D++EC C C+N
Sbjct: 5200 SPCHQRCFNAIGS--FHC-GCEPGYQLKGRKCMDVNECRQ-NVCRPDQHCKNTR-GGYKC 5254
Query: 196 XXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGS 255
++ GT C+D+DEC DG C ++C NT +GS
Sbjct: 5255 IDLCPNGMTKAENGT--------CIDIDECKDGTHQCRYNQICENT-----------RGS 5295
Query: 256 YICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTG--WTGNGTV 313
Y CV G+ RPC D + + P + N F KC+C G G+G
Sbjct: 5296 YRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSF--KCICPPGQHLLGDGKS 5353
Query: 314 C-GLDR 318
C GL+R
Sbjct: 5354 CAGLER 5359
Score = 66.5 bits (155), Expect = 4e-10
Identities = 55/174 (31%), Positives = 79/174 (45%), Gaps = 23/174 (13%)
Query: 21 GERCVDTDQGFRCE-RCPGS--QTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCG 74
G+ C +T +RC RC +TSDG +C+ N C PC G + CG
Sbjct: 5161 GQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQ---DINECQESS-PCHQRCFNAIGSFHCG 5216
Query: 75 KCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYGPKC-GSCPTGYV-GDGRQCQHV-- 129
C G+ G +C ++ CR N C C+ T+ G KC CP G + C +
Sbjct: 5217 -CEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDE 5275
Query: 130 C-DAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLI-RPC 179
C D C + C ++T Y C CP GY Q G C+D++EC+ + +PC
Sbjct: 5276 CKDGTHQCRYNQIC--ENTRGSYRCV-CPRGYRSQGVGRPCMDINECEQVPKPC 5326
Score = 55.2 bits (127), Expect = 9e-07
Identities = 63/250 (25%), Positives = 95/250 (38%), Gaps = 39/250 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCGKCPSGF 80
C +T +RC CP S G R N C PC G ++C CP G
Sbjct: 5289 CENTRGSYRCV-CPRGYRSQG-VGRPCMDINECEQVPKPCAHQCSNTPGSFKC-ICPPGQ 5345
Query: 81 H--GNGVECYRISCRANTCFQGVSCEETQYGPKCGSC-PTGYVGDGRQCQHVCDAQKPCG 137
H G+G C + N Q S ++ P + P + RQ H+ +
Sbjct: 5346 HLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHY---RQYSHLYSSYSEYR 5402
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX 197
R + ++ + CP G + + TCVD+DEC+ C C+N
Sbjct: 5403 NSRTSLSRTRRTIRKT--CPEGSEASHDTCVDIDECENTDACQH--ECKN-------TFG 5451
Query: 198 XXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYI 257
G++ T N + C D+DEC + +C R+C N ++GSY
Sbjct: 5452 SYQCICPPGYQLTHNGKT---CQDIDECLEQNVHCGPNRMCFN-----------MRGSYQ 5497
Query: 258 CV--PCGGHY 265
C+ PC +Y
Sbjct: 5498 CIDTPCPPNY 5507
Score = 38.3 bits (85), Expect = 0.11
Identities = 63/227 (27%), Positives = 85/227 (37%), Gaps = 46/227 (20%)
Query: 109 GPKCGSCPTGYVGD--GRQC--QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW-- 162
G + CP+G+ D G C + C A PC C + YY C CP G
Sbjct: 5086 GDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CH-NAMGTYY-CS-CPKGLTIAA 5140
Query: 163 NGYTCVDMDECDLIR-PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVD 221
+G TC D+DEC L R C C N G+R T + C D
Sbjct: 5141 DGRTCQDIDECALGRHTCHAGQDCDN-----TIGSYRCVVRCGSGFRRTSDGL---SCQD 5192
Query: 222 VDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK 281
++EC + + P + C N GS+ C C Y + R C D + +
Sbjct: 5193 INECQE---SSPCHQRCFNA-----------IGSFHC-GCEPGYQLK-GRKCMDVNECRQ 5236
Query: 282 R-CDP-SYCRRFNAVCGFGQKCV--CNTGWT--GNGTVCGLDRDLDG 322
C P +C+ G KC+ C G T NGT +D DG
Sbjct: 5237 NVCRPDQHCKNTRG----GYKCIDLCPNGMTKAENGTCIDIDECKDG 5279
>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
Length = 5635
Score = 87.0 bits (206), Expect = 2e-16
Identities = 90/306 (29%), Positives = 123/306 (40%), Gaps = 47/306 (15%)
Query: 29 QGFRCERCPGSQTSD--GQTC--RTACSA-NPCFGGRVPCQDLPDGRYQCGKCPSGFH-- 81
+G R +CP T D G C C+A NPC C + G Y C CP G
Sbjct: 5085 KGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS---CHNAM-GTYYCS-CPKGLTIA 5139
Query: 82 GNGVECYRIS-CRA--NTCFQGVSCEETQYGPKCG-SCPTGY--VGDGRQCQHVCDAQKP 135
+G C I C +TC G C+ T +C C +G+ DG CQ + + Q+
Sbjct: 5140 ADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQES 5199
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXX 195
+RC S + C GC GYQ G C+D++EC C C+N
Sbjct: 5200 SPCHQRCFNAIGS--FHC-GCEPGYQLKGRKCMDVNECRQ-NVCRPDQHCKNTR-GGYKC 5254
Query: 196 XXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGS 255
++ GT C+D+DEC DG C ++C NT +GS
Sbjct: 5255 IDLCPNGMTKAENGT--------CIDIDECKDGTHQCRYNQICENT-----------RGS 5295
Query: 256 YICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTG--WTGNGTV 313
Y CV G+ RPC D + + P + N F KC+C G G+G
Sbjct: 5296 YRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSF--KCICPPGQHLLGDGKS 5353
Query: 314 C-GLDR 318
C GL+R
Sbjct: 5354 CAGLER 5359
Score = 66.5 bits (155), Expect = 4e-10
Identities = 55/174 (31%), Positives = 79/174 (45%), Gaps = 23/174 (13%)
Query: 21 GERCVDTDQGFRCE-RCPGS--QTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCG 74
G+ C +T +RC RC +TSDG +C+ N C PC G + CG
Sbjct: 5161 GQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQ---DINECQESS-PCHQRCFNAIGSFHCG 5216
Query: 75 KCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYGPKC-GSCPTGYV-GDGRQCQHV-- 129
C G+ G +C ++ CR N C C+ T+ G KC CP G + C +
Sbjct: 5217 -CEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDE 5275
Query: 130 C-DAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLI-RPC 179
C D C + C ++T Y C CP GY Q G C+D++EC+ + +PC
Sbjct: 5276 CKDGTHQCRYNQIC--ENTRGSYRCV-CPRGYRSQGVGRPCMDINECEQVPKPC 5326
Score = 55.2 bits (127), Expect = 9e-07
Identities = 63/250 (25%), Positives = 95/250 (38%), Gaps = 39/250 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCGKCPSGF 80
C +T +RC CP S G R N C PC G ++C CP G
Sbjct: 5289 CENTRGSYRCV-CPRGYRSQG-VGRPCMDINECEQVPKPCAHQCSNTPGSFKC-ICPPGQ 5345
Query: 81 H--GNGVECYRISCRANTCFQGVSCEETQYGPKCGSC-PTGYVGDGRQCQHVCDAQKPCG 137
H G+G C + N Q S ++ P + P + RQ H+ +
Sbjct: 5346 HLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHY---RQYSHLYSSYSEYR 5402
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX 197
R + ++ + CP G + + TCVD+DEC+ C C+N
Sbjct: 5403 NSRTSLSRTRRTIRKT--CPEGSEASHDTCVDIDECENTDACQH--ECKN-------TFG 5451
Query: 198 XXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYI 257
G++ T N + C D+DEC + +C R+C N ++GSY
Sbjct: 5452 SYQCICPPGYQLTHNGKT---CQDIDECLEQNVHCGPNRMCFN-----------MRGSYQ 5497
Query: 258 CV--PCGGHY 265
C+ PC +Y
Sbjct: 5498 CIDTPCPPNY 5507
Score = 38.3 bits (85), Expect = 0.11
Identities = 63/227 (27%), Positives = 85/227 (37%), Gaps = 46/227 (20%)
Query: 109 GPKCGSCPTGYVGD--GRQC--QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW-- 162
G + CP+G+ D G C + C A PC C + YY C CP G
Sbjct: 5086 GDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CH-NAMGTYY-CS-CPKGLTIAA 5140
Query: 163 NGYTCVDMDECDLIR-PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVD 221
+G TC D+DEC L R C C N G+R T + C D
Sbjct: 5141 DGRTCQDIDECALGRHTCHAGQDCDN-----TIGSYRCVVRCGSGFRRTSDGL---SCQD 5192
Query: 222 VDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK 281
++EC + + P + C N GS+ C C Y + R C D + +
Sbjct: 5193 INECQE---SSPCHQRCFNA-----------IGSFHC-GCEPGYQLK-GRKCMDVNECRQ 5236
Query: 282 R-CDP-SYCRRFNAVCGFGQKCV--CNTGWT--GNGTVCGLDRDLDG 322
C P +C+ G KC+ C G T NGT +D DG
Sbjct: 5237 NVCRPDQHCKNTRG----GYKCIDLCPNGMTKAENGTCIDIDECKDG 5279
>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
Length = 2673
Score = 87.0 bits (206), Expect = 2e-16
Identities = 90/306 (29%), Positives = 123/306 (40%), Gaps = 47/306 (15%)
Query: 29 QGFRCERCPGSQTSD--GQTC--RTACSA-NPCFGGRVPCQDLPDGRYQCGKCPSGFH-- 81
+G R +CP T D G C C+A NPC C + G Y C CP G
Sbjct: 2123 KGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS---CHNAM-GTYYCS-CPKGLTIA 2177
Query: 82 GNGVECYRIS-CRA--NTCFQGVSCEETQYGPKCG-SCPTGY--VGDGRQCQHVCDAQKP 135
+G C I C +TC G C+ T +C C +G+ DG CQ + + Q+
Sbjct: 2178 ADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQES 2237
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXX 195
+RC S + C GC GYQ G C+D++EC C C+N
Sbjct: 2238 SPCHQRCFNAIGS--FHC-GCEPGYQLKGRKCMDVNECRQ-NVCRPDQHCKNTR-GGYKC 2292
Query: 196 XXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGS 255
++ GT C+D+DEC DG C ++C NT +GS
Sbjct: 2293 IDLCPNGMTKAENGT--------CIDIDECKDGTHQCRYNQICENT-----------RGS 2333
Query: 256 YICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTG--WTGNGTV 313
Y CV G+ RPC D + + P + N F KC+C G G+G
Sbjct: 2334 YRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSF--KCICPPGQHLLGDGKS 2391
Query: 314 C-GLDR 318
C GL+R
Sbjct: 2392 CAGLER 2397
Score = 66.5 bits (155), Expect = 4e-10
Identities = 55/174 (31%), Positives = 79/174 (45%), Gaps = 23/174 (13%)
Query: 21 GERCVDTDQGFRCE-RCPGS--QTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCG 74
G+ C +T +RC RC +TSDG +C+ N C PC G + CG
Sbjct: 2199 GQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQ---DINECQESS-PCHQRCFNAIGSFHCG 2254
Query: 75 KCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYGPKC-GSCPTGYV-GDGRQCQHV-- 129
C G+ G +C ++ CR N C C+ T+ G KC CP G + C +
Sbjct: 2255 -CEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDE 2313
Query: 130 C-DAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLI-RPC 179
C D C + C ++T Y C CP GY Q G C+D++EC+ + +PC
Sbjct: 2314 CKDGTHQCRYNQIC--ENTRGSYRCV-CPRGYRSQGVGRPCMDINECEQVPKPC 2364
Score = 55.2 bits (127), Expect = 9e-07
Identities = 63/250 (25%), Positives = 95/250 (38%), Gaps = 39/250 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCGKCPSGF 80
C +T +RC CP S G R N C PC G ++C CP G
Sbjct: 2327 CENTRGSYRCV-CPRGYRSQG-VGRPCMDINECEQVPKPCAHQCSNTPGSFKC-ICPPGQ 2383
Query: 81 H--GNGVECYRISCRANTCFQGVSCEETQYGPKCGSC-PTGYVGDGRQCQHVCDAQKPCG 137
H G+G C + N Q S ++ P + P + RQ H+ +
Sbjct: 2384 HLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHY---RQYSHLYSSYSEYR 2440
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX 197
R + ++ + CP G + + TCVD+DEC+ C C+N
Sbjct: 2441 NSRTSLSRTRRTIRKT--CPEGSEASHDTCVDIDECENTDACQH--ECKN-------TFG 2489
Query: 198 XXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYI 257
G++ T N + C D+DEC + +C R+C N ++GSY
Sbjct: 2490 SYQCICPPGYQLTHNGKT---CQDIDECLEQNVHCGPNRMCFN-----------MRGSYQ 2535
Query: 258 CV--PCGGHY 265
C+ PC +Y
Sbjct: 2536 CIDTPCPPNY 2545
Score = 38.3 bits (85), Expect = 0.11
Identities = 63/227 (27%), Positives = 85/227 (37%), Gaps = 46/227 (20%)
Query: 109 GPKCGSCPTGYVGD--GRQC--QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW-- 162
G + CP+G+ D G C + C A PC C + YY C CP G
Sbjct: 2124 GDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CH-NAMGTYY-CS-CPKGLTIAA 2178
Query: 163 NGYTCVDMDECDLIR-PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVD 221
+G TC D+DEC L R C C N G+R T + C D
Sbjct: 2179 DGRTCQDIDECALGRHTCHAGQDCDN-----TIGSYRCVVRCGSGFRRTSDGL---SCQD 2230
Query: 222 VDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK 281
++EC + + P + C N GS+ C C Y + R C D + +
Sbjct: 2231 INECQE---SSPCHQRCFNA-----------IGSFHC-GCEPGYQLK-GRKCMDVNECRQ 2274
Query: 282 R-CDP-SYCRRFNAVCGFGQKCV--CNTGWT--GNGTVCGLDRDLDG 322
C P +C+ G KC+ C G T NGT +D DG
Sbjct: 2275 NVCRPDQHCKNTRG----GYKCIDLCPNGMTKAENGTCIDIDECKDG 2317
>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
Length = 5636
Score = 86.6 bits (205), Expect = 3e-16
Identities = 90/306 (29%), Positives = 122/306 (39%), Gaps = 47/306 (15%)
Query: 29 QGFRCERCPGSQTSD--GQTC--RTACSA-NPCFGGRVPCQDLPDGRYQCGKCPSGFH-- 81
+G R +CP T D G C C+A NPC C + G Y C CP G
Sbjct: 5086 KGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS---CHNAM-GTYYCS-CPKGLTIA 5140
Query: 82 GNGVECYRIS-CRA--NTCFQGVSCEETQYGPKCG-SCPTGY--VGDGRQCQHVCDAQKP 135
+G C I C +TC G C+ T +C C +G+ DG CQ + + Q+
Sbjct: 5141 ADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQES 5200
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXX 195
+RC S + C GC GYQ G C+D++EC C C+N
Sbjct: 5201 SPCHQRCFNAIGS--FHC-GCEPGYQLKGRKCMDVNECRQ-NVCRPDQHCKNTR-GGYKC 5255
Query: 196 XXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGS 255
++ GT C+D+DEC DG C ++C NT + S
Sbjct: 5256 IDLCPNGMTKAENGT--------CIDIDECKDGTHQCRYNQICENT-----------RSS 5296
Query: 256 YICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTG--WTGNGTV 313
Y CV G+ RPC D D + P + N F KC+C G G+G
Sbjct: 5297 YRCVCPRGYRSQGVGRPCMDIDECEQVPKPCAHQCSNTPGSF--KCICPPGQHLLGDGKS 5354
Query: 314 C-GLDR 318
C GL+R
Sbjct: 5355 CAGLER 5360
Score = 68.9 bits (161), Expect = 7e-11
Identities = 56/174 (32%), Positives = 79/174 (45%), Gaps = 23/174 (13%)
Query: 21 GERCVDTDQGFRCE-RCPGS--QTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCG 74
G+ C +T +RC RC +TSDG +C+ N C PC G + CG
Sbjct: 5162 GQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQ---DINECQESS-PCHQRCFNAIGSFHCG 5217
Query: 75 KCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYGPKC-GSCPTGYV-GDGRQCQHV-- 129
C G+ G +C ++ CR N C C+ T+ G KC CP G + C +
Sbjct: 5218 -CEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDE 5276
Query: 130 C-DAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLI-RPC 179
C D C + C ++T Y C CP GY Q G C+D+DEC+ + +PC
Sbjct: 5277 CKDGTHQCRYNQIC--ENTRSSYRCV-CPRGYRSQGVGRPCMDIDECEQVPKPC 5327
Score = 54.0 bits (124), Expect = 2e-06
Identities = 62/250 (24%), Positives = 95/250 (38%), Gaps = 39/250 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCGKCPSGF 80
C +T +RC CP S G R + C PC G ++C CP G
Sbjct: 5290 CENTRSSYRCV-CPRGYRSQG-VGRPCMDIDECEQVPKPCAHQCSNTPGSFKC-ICPPGQ 5346
Query: 81 H--GNGVECYRISCRANTCFQGVSCEETQYGPKCGSC-PTGYVGDGRQCQHVCDAQKPCG 137
H G+G C + N Q S ++ P + P + RQ H+ +
Sbjct: 5347 HLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHY---RQYSHLYSSYSEYR 5403
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX 197
R + ++ + CP G + + TCVD+DEC+ C C+N
Sbjct: 5404 NSRTSLSRTRRTIRKT--CPEGSEASHDTCVDIDECENTDACQH--ECKN-------TFG 5452
Query: 198 XXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYI 257
G++ T N + C D+DEC + +C R+C N ++GSY
Sbjct: 5453 SYQCICPPGYQLTHNGKT---CQDIDECLEQNVHCGPNRMCFN-----------MRGSYQ 5498
Query: 258 CV--PCGGHY 265
C+ PC +Y
Sbjct: 5499 CIDTPCPPNY 5508
Score = 38.3 bits (85), Expect = 0.11
Identities = 63/227 (27%), Positives = 85/227 (37%), Gaps = 46/227 (20%)
Query: 109 GPKCGSCPTGYVGD--GRQC--QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW-- 162
G + CP+G+ D G C + C A PC C + YY C CP G
Sbjct: 5087 GDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHS--CH-NAMGTYY-CS-CPKGLTIAA 5141
Query: 163 NGYTCVDMDECDLIR-PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVD 221
+G TC D+DEC L R C C N G+R T + C D
Sbjct: 5142 DGRTCQDIDECALGRHTCHAGQDCDN-----TIGSYRCVVRCGSGFRRTSDGL---SCQD 5193
Query: 222 VDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK 281
++EC + + P + C N GS+ C C Y + R C D + +
Sbjct: 5194 INECQE---SSPCHQRCFNA-----------IGSFHC-GCEPGYQLK-GRKCMDVNECRQ 5237
Query: 282 R-CDP-SYCRRFNAVCGFGQKCV--CNTGWT--GNGTVCGLDRDLDG 322
C P +C+ G KC+ C G T NGT +D DG
Sbjct: 5238 NVCRPDQHCKNTRG----GYKCIDLCPNGMTKAENGTCIDIDECKDG 5280
>AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 85.8 bits (203), Expect = 5e-16
Identities = 53/170 (31%), Positives = 75/170 (44%), Gaps = 9/170 (5%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
CV C D+ G++C+ PG ++ C +NPC G C+D+ G Y C C
Sbjct: 725 CVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGT-CKDMTSG-YVC-TCRE 781
Query: 79 GFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGR 138
GF G + C +N C +C + G KC +C Y G + A PC
Sbjct: 782 GFSGPNCQTNINECASNPCLNQGTCIDDVAGYKC-NCLLPYTGATCEVVLAPCAPSPCRN 840
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C + C CP+G W G TC VD++EC ++ PC SC+N
Sbjct: 841 GGECRQSEDYESFSCV-CPTG--WQGQTCEVDINEC-VLSPCRHGASCQN 886
Score = 63.3 bits (147), Expect = 3e-09
Identities = 46/155 (29%), Positives = 60/155 (38%), Gaps = 12/155 (7%)
Query: 22 ERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPS 78
+ CV F CE C T G+ C + C PC G R KCP+
Sbjct: 1282 QNCVQRVNDFHCE-CRAGHT--GRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPA 1338
Query: 79 GFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQ--CQHVCDAQKPC 136
GF G E +C + C G +C P C C + G Q C PC
Sbjct: 1339 GFEGATCENDARTCGSLRCLNGGTCISGPRSPTC-LCLGPFTGPECQFPASSPCLGGNPC 1397
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMD 171
+ C P S SP+Y C CP+ ++NG C +D
Sbjct: 1398 YNQGTCEPTSESPFYRCL-CPA--KFNGLLCHILD 1429
Score = 60.9 bits (141), Expect = 2e-08
Identities = 77/303 (25%), Positives = 109/303 (35%), Gaps = 34/303 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C+D G++C C T G TC C+ +PC G C+ D CP+G+
Sbjct: 806 CIDDVAGYKCN-CLLPYT--GATCEVVLAPCAPSPCRNGG-ECRQSEDYESFSCVCPTGW 861
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C + C G SC+ T G +C C GY GR C+ D PC
Sbjct: 862 QGQTCEVDINECVLSPCRHGASCQNTHGGYRC-HCQAGY--SGRNCETDIDDCRPNPCHN 918
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXX 197
C + + C+ C G++ G C D++EC PC + +C +
Sbjct: 919 GGSCTDGINTAF--CD-CLPGFR--GTFCEEDINEC-ASDPCRNGANC--TDCVDSYTCT 970
Query: 198 XXXXXXSQGWRGTGNERRREHCVDVDECADG----RANCPRGRLCVNTPQYPSNPVSS-- 251
+ C + C DG CP G + Q+ N S
Sbjct: 971 CPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPG-FTGSYCQHDVNECDSQP 1029
Query: 252 -LQGSYICVPCGGHYYVNTTRPCFDPD--SLVKRCDPSYCRRFNAV--CGFGQKCVCNTG 306
L G C G Y + P+ +LV CD S C+ +C C +G
Sbjct: 1030 CLHGG-TCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSG 1088
Query: 307 WTG 309
WTG
Sbjct: 1089 WTG 1091
Score = 59.3 bits (137), Expect = 5e-08
Identities = 54/174 (31%), Positives = 64/174 (36%), Gaps = 18/174 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRT---ACSANP--CFGGRVPCQDLPDGRYQCGK 75
G CVD + C RCP T GQ C C P C G C + G Y C
Sbjct: 269 GGACVDGVNTYNC-RCPPEWT--GQYCTEDVDECQLMPNACQNGGT-CHNTHGG-YNC-V 322
Query: 76 CPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
C +G+ G C + CF G +C + C CP G G C P
Sbjct: 323 CVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYC-ECPHGRTGLLCHLNDAC-ISNP 380
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDL-IRPCDDLVSCRN 187
C C + C CPSGY G C D+DEC L PC+ C N
Sbjct: 381 CNEGSNCDTNPVNGKAICT-CPSGY--TGPACSQDVDECSLGANPCEHAGKCIN 431
Score = 59.3 bits (137), Expect = 5e-08
Identities = 88/317 (27%), Positives = 116/317 (36%), Gaps = 50/317 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C D F C PG +T CS+ PC G CQD D Y C C G G
Sbjct: 580 CKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGT-CQDR-DNAYLCF-CLKGTTGP 636
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
E C ++ C G +C + G +C +C GY G C D A PC
Sbjct: 637 NCEINLDDCASSPCDSG-TCLDKIDGYEC-ACEPGYTGS--MCNINIDECAGNPCHNGGT 692
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C + C CP GY + TC+ +++EC+ PC +CR+
Sbjct: 693 CEDGING--FTCR-CPEGY--HDPTCLSEVNECNS-NPCVH-GACRDS-------LNGYK 738
Query: 201 XXXSQGWRGTG-----NERRREHCVDVDECADGRAN----CPRG----RLCVNTPQYPSN 247
GW GT NE CV+ C D + C G N + SN
Sbjct: 739 CDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASN 798
Query: 248 PVSSLQGSYICVPCGGHYYVNTTRPCFDP--DSLVKRCDPSYCRRFNAVCGFGQ-----K 300
P + QG+ C+ Y N P + ++ C PS CR C +
Sbjct: 799 PCLN-QGT--CIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRN-GGECRQSEDYESFS 854
Query: 301 CVCNTGWTGNGTVCGLD 317
CVC TGW G C +D
Sbjct: 855 CVCPTGW--QGQTCEVD 869
Score = 58.4 bits (135), Expect = 9e-08
Identities = 48/169 (28%), Positives = 74/169 (43%), Gaps = 15/169 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D D + C G+ + + C+++PC G C D DG Y+C C G+
Sbjct: 615 GGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGT--CLDKIDG-YECA-CEPGY 670
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA-QKPCGRE 139
G+ C N C G +CE+ G C CP GY D V + PC
Sbjct: 671 TGSMCNINIDECAGNPCHNGGTCEDGINGFTC-RCPEGY-HDPTCLSEVNECNSNPC-VH 727
Query: 140 RRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C + + Y+C+ C G W+G C ++ +EC+ PC + +C++
Sbjct: 728 GAC--RDSLNGYKCD-CDPG--WSGTNCDINNNECE-SNPCVNGGTCKD 770
Score = 58.0 bits (134), Expect = 1e-07
Identities = 51/176 (28%), Positives = 70/176 (39%), Gaps = 21/176 (11%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G CVD F C PG S Q C + PC G CQD G Y+C CP G+
Sbjct: 995 GGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGT-CQD-GCGSYRC-TCPQGY 1051
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-----DGRQCQHVC----- 130
G + C ++ C G C +T +C CP+G+ G C+
Sbjct: 1052 TGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRC-ECPSGWTGLYCDVPSVSCEVAAQRQGV 1110
Query: 131 DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDM-DECDLIRPCDDLVSC 185
D + C C+ + + C C +GY G C D+ DEC PC + +C
Sbjct: 1111 DVARLCQHGGLCVDAGNT--HHCR-CQAGY--TGSYCEDLVDECS-PSPCQNGATC 1160
Score = 56.8 bits (131), Expect = 3e-07
Identities = 86/349 (24%), Positives = 124/349 (35%), Gaps = 47/349 (13%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C +T G+RC G + +T C NPC G C D + + C C GF
Sbjct: 881 GASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGG-SCTDGINTAF-C-DCLPGF 937
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
G E C ++ C G +C + C +CP G+ G + + C
Sbjct: 938 RGTFCEEDINECASDPCRNGANCTDCVDSYTC-TCPAGFSGIHCENNTPDCTESSCFNGG 996
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C+ S + C CP G+ Y D++ECD +PC +C++
Sbjct: 997 TCVDGINS--FTCL-CPPGFT-GSYCQHDVNECD-SQPCLHGGTCQD-------GCGSYR 1044
Query: 201 XXXSQGWRGTGNERRREHCVDVDECADG----------RANCPRG--RLCVNTPQYPSNP 248
QG+ G N + H D C +G R CP G L + P
Sbjct: 1045 CTCPQGYTGP-NCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEV 1103
Query: 249 VSSLQG---------SYICVPCGGHYYVNTTRPCFDP--DSLVKRCDPSYCRRFNAVCG- 296
+ QG +CV G ++ + LV C PS C+ A C
Sbjct: 1104 AAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQN-GATCTD 1162
Query: 297 --FGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQ-LPCNE-PRCKKDNCP 341
G C C G+ G +D L HP + C + P K +CP
Sbjct: 1163 YLGGYSCKCVAGYHGVNCSEEIDECL-SHPCQNGGTCLDLPNTYKCSCP 1210
Score = 48.8 bits (111), Expect = 8e-05
Identities = 83/334 (24%), Positives = 123/334 (36%), Gaps = 52/334 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCF-GGRVPCQDLPDGRYQCGKCPSGFHG 82
C+D F+C PG + + C+++PC GR C D + +QC +CP+GF G
Sbjct: 467 CLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGR--CLDKIN-EFQC-ECPTGFTG 522
Query: 83 NGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQKPCGRERR 141
+ + C + C G C + C C GY G + CD PC
Sbjct: 523 HLCQYDVDECASTPCKNGAKCLDGPNTYTC-VCTEGYTGTHCEVDIDECDPD-PC-HYGS 579
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C K + C C GY G+ C +++EC +PC +C++ +
Sbjct: 580 C--KDGVATFTCL-CRPGY--TGHHCETNINECS-SQPCRHGGTCQDRDNAYLCFCL--- 630
Query: 201 XXXSQGWRGTGNERRREHCV----DVDECADG----RANCP---RGRLC-VNTPQYPSNP 248
+G G E + C D C D C G +C +N + NP
Sbjct: 631 ----KGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNP 686
Query: 249 VSSLQGSYICVPCGGHYYVNTTRPCFDPDSL--VKRCDPSYCRRFNAVCG---FGQKCVC 303
C + DP L V C+ + C + C G KC C
Sbjct: 687 ---CHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPC--VHGACRDSLNGYKCDC 741
Query: 304 NTGWTGNGTVCGLDRDLDGHPDEQLPC-NEPRCK 336
+ GW +GT C D++ + E PC N CK
Sbjct: 742 DPGW--SGTNC----DINNNECESNPCVNGGTCK 769
Score = 47.2 bits (107), Expect = 2e-04
Identities = 43/168 (25%), Positives = 65/168 (38%), Gaps = 13/168 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G +C+D + C G + + C +PC G C+D + C C G+
Sbjct: 540 GAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG--SCKD-GVATFTC-LCRPGY 595
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
G+ E C + C G +C++ C C G G + A PC
Sbjct: 596 TGHHCETNINECSSQPCRHGGTCQDRDNAYLC-FCLKGTTGPNCEINLDDCASSPCD-SG 653
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C+ K YEC C GY G C +++DEC PC + +C +
Sbjct: 654 TCLDKIDG--YEC-ACEPGY--TGSMCNINIDEC-AGNPCHNGGTCED 695
Score = 46.4 bits (105), Expect = 4e-04
Identities = 50/161 (31%), Positives = 65/161 (40%), Gaps = 33/161 (20%)
Query: 31 FRCERCPGSQTSDGQTCRTA--CSANPCFGGRVPCQDLP-DGRYQCGKCPSGFHG----- 82
++C RCP + G++C+ A C++NPC G Q LP + Y C CP FHG
Sbjct: 125 YKC-RCPPGWS--GKSCQQADPCASNPCANGG---QCLPFEASYIC-HCPPSFHGPTCRQ 177
Query: 83 NGVECYRIS--CR-ANTCFQGVS-----CEETQYGPKCG----SCPTGYVGDGRQCQHVC 130
+ EC + CR TC V C T GP C C +G C+
Sbjct: 178 DVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTG 237
Query: 131 DAQKPCGRERRCMPKSTSPYYE--CEGCPSGYQWNGYTCVD 169
D C C+P T E + CP NG CVD
Sbjct: 238 DVTHECA----CLPGFTGQNCEENIDDCPGNNCKNGGACVD 274
Score = 45.6 bits (103), Expect = 7e-04
Identities = 43/148 (29%), Positives = 58/148 (39%), Gaps = 20/148 (13%)
Query: 35 RCPGSQTSDGQTCR---TACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS 91
RC T G C CS +PC G C+ D ++C C GF G E
Sbjct: 203 RCVCRATHTGPNCERPYVPCSPSPCQNGGT-CRPTGDVTHECA-CLPGFTGQNCEENIDD 260
Query: 92 CRANTCFQGVSCEETQYGPKCGSCPTGYVG-----DGRQCQHVCDAQKPCGRERRCMPKS 146
C N C G +C + C CP + G D +CQ + +A C C +
Sbjct: 261 CPGNNCKNGGACVDGVNTYNC-RCPPEWTGQYCTEDVDECQLMPNA---CQNGGTC--HN 314
Query: 147 TSPYYECEGCPSGYQWNGYTCVD-MDEC 173
T Y C C +G W G C + +D+C
Sbjct: 315 THGGYNCV-CVNG--WTGEDCSENIDDC 339
Score = 43.2 bits (97), Expect = 0.004
Identities = 51/172 (29%), Positives = 74/172 (43%), Gaps = 25/172 (14%)
Query: 21 GERCVDTDQGFRCERCP-GSQTSDGQTCRTAC-------SANP-CFGGRVPCQDLPDGRY 71
G C+D ++C CP G+Q + C S +P CF C D G Y
Sbjct: 1195 GGTCLDLPNTYKCS-CPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGT-CVDQVGG-Y 1251
Query: 72 QCGKCPSGFHGNGVECYRISCRANTC-FQGV-SCEETQYGPKCGSCPTGYVGDGRQCQHV 129
C CP GF G E C +N C +G +C + C C G+ GR+C+ V
Sbjct: 1252 SC-TCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHC-ECRAGHT--GRRCESV 1307
Query: 130 CDA--QKPCGRERRC-MPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIR 177
+ KPC C + +T+ + C+ CP+G++ G TC D C +R
Sbjct: 1308 INGCKGKPCKNGGTCAVASNTARGFICK-CPAGFE--GATCENDARTCGSLR 1356
>AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 85.8 bits (203), Expect = 5e-16
Identities = 53/170 (31%), Positives = 75/170 (44%), Gaps = 9/170 (5%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
CV C D+ G++C+ PG ++ C +NPC G C+D+ G Y C C
Sbjct: 725 CVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGT-CKDMTSG-YVC-TCRE 781
Query: 79 GFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGR 138
GF G + C +N C +C + G KC +C Y G + A PC
Sbjct: 782 GFSGPNCQTNINECASNPCLNQGTCIDDVAGYKC-NCLLPYTGATCEVVLAPCAPSPCRN 840
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C + C CP+G W G TC VD++EC ++ PC SC+N
Sbjct: 841 GGECRQSEDYESFSCV-CPTG--WQGQTCEVDINEC-VLSPCRHGASCQN 886
Score = 63.3 bits (147), Expect = 3e-09
Identities = 46/155 (29%), Positives = 60/155 (38%), Gaps = 12/155 (7%)
Query: 22 ERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPS 78
+ CV F CE C T G+ C + C PC G R KCP+
Sbjct: 1282 QNCVQRVNDFHCE-CRAGHT--GRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPA 1338
Query: 79 GFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQ--CQHVCDAQKPC 136
GF G E +C + C G +C P C C + G Q C PC
Sbjct: 1339 GFEGATCENDARTCGSLRCLNGGTCISGPRSPTC-LCLGPFTGPECQFPASSPCLGGNPC 1397
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMD 171
+ C P S SP+Y C CP+ ++NG C +D
Sbjct: 1398 YNQGTCEPTSESPFYRCL-CPA--KFNGLLCHILD 1429
Score = 60.9 bits (141), Expect = 2e-08
Identities = 77/303 (25%), Positives = 109/303 (35%), Gaps = 34/303 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C+D G++C C T G TC C+ +PC G C+ D CP+G+
Sbjct: 806 CIDDVAGYKCN-CLLPYT--GATCEVVLAPCAPSPCRNGG-ECRQSEDYESFSCVCPTGW 861
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C + C G SC+ T G +C C GY GR C+ D PC
Sbjct: 862 QGQTCEVDINECVLSPCRHGASCQNTHGGYRC-HCQAGY--SGRNCETDIDDCRPNPCHN 918
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXX 197
C + + C+ C G++ G C D++EC PC + +C +
Sbjct: 919 GGSCTDGINTAF--CD-CLPGFR--GTFCEEDINEC-ASDPCRNGANC--TDCVDSYTCT 970
Query: 198 XXXXXXSQGWRGTGNERRREHCVDVDECADG----RANCPRGRLCVNTPQYPSNPVSS-- 251
+ C + C DG CP G + Q+ N S
Sbjct: 971 CPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPG-FTGSYCQHDVNECDSQP 1029
Query: 252 -LQGSYICVPCGGHYYVNTTRPCFDPD--SLVKRCDPSYCRRFNAV--CGFGQKCVCNTG 306
L G C G Y + P+ +LV CD S C+ +C C +G
Sbjct: 1030 CLHGG-TCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSG 1088
Query: 307 WTG 309
WTG
Sbjct: 1089 WTG 1091
Score = 59.3 bits (137), Expect = 5e-08
Identities = 54/174 (31%), Positives = 64/174 (36%), Gaps = 18/174 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRT---ACSANP--CFGGRVPCQDLPDGRYQCGK 75
G CVD + C RCP T GQ C C P C G C + G Y C
Sbjct: 269 GGACVDGVNTYNC-RCPPEWT--GQYCTEDVDECQLMPNACQNGGT-CHNTHGG-YNC-V 322
Query: 76 CPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
C +G+ G C + CF G +C + C CP G G C P
Sbjct: 323 CVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYC-ECPHGRTGLLCHLNDAC-ISNP 380
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDL-IRPCDDLVSCRN 187
C C + C CPSGY G C D+DEC L PC+ C N
Sbjct: 381 CNEGSNCDTNPVNGKAICT-CPSGY--TGPACSQDVDECSLGANPCEHAGKCIN 431
Score = 59.3 bits (137), Expect = 5e-08
Identities = 88/317 (27%), Positives = 116/317 (36%), Gaps = 50/317 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C D F C PG +T CS+ PC G CQD D Y C C G G
Sbjct: 580 CKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGT-CQDR-DNAYLCF-CLKGTTGP 636
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
E C ++ C G +C + G +C +C GY G C D A PC
Sbjct: 637 NCEINLDDCASSPCDSG-TCLDKIDGYEC-ACEPGYTGS--MCNINIDECAGNPCHNGGT 692
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C + C CP GY + TC+ +++EC+ PC +CR+
Sbjct: 693 CEDGING--FTCR-CPEGY--HDPTCLSEVNECNS-NPCVH-GACRDS-------LNGYK 738
Query: 201 XXXSQGWRGTG-----NERRREHCVDVDECADGRAN----CPRG----RLCVNTPQYPSN 247
GW GT NE CV+ C D + C G N + SN
Sbjct: 739 CDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASN 798
Query: 248 PVSSLQGSYICVPCGGHYYVNTTRPCFDP--DSLVKRCDPSYCRRFNAVCGFGQ-----K 300
P + QG+ C+ Y N P + ++ C PS CR C +
Sbjct: 799 PCLN-QGT--CIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRN-GGECRQSEDYESFS 854
Query: 301 CVCNTGWTGNGTVCGLD 317
CVC TGW G C +D
Sbjct: 855 CVCPTGW--QGQTCEVD 869
Score = 58.4 bits (135), Expect = 9e-08
Identities = 48/169 (28%), Positives = 74/169 (43%), Gaps = 15/169 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D D + C G+ + + C+++PC G C D DG Y+C C G+
Sbjct: 615 GGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGT--CLDKIDG-YECA-CEPGY 670
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA-QKPCGRE 139
G+ C N C G +CE+ G C CP GY D V + PC
Sbjct: 671 TGSMCNINIDECAGNPCHNGGTCEDGINGFTC-RCPEGY-HDPTCLSEVNECNSNPC-VH 727
Query: 140 RRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C + + Y+C+ C G W+G C ++ +EC+ PC + +C++
Sbjct: 728 GAC--RDSLNGYKCD-CDPG--WSGTNCDINNNECE-SNPCVNGGTCKD 770
Score = 58.0 bits (134), Expect = 1e-07
Identities = 51/176 (28%), Positives = 70/176 (39%), Gaps = 21/176 (11%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G CVD F C PG S Q C + PC G CQD G Y+C CP G+
Sbjct: 995 GGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGT-CQD-GCGSYRC-TCPQGY 1051
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-----DGRQCQHVC----- 130
G + C ++ C G C +T +C CP+G+ G C+
Sbjct: 1052 TGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRC-ECPSGWTGLYCDVPSVSCEVAAQRQGV 1110
Query: 131 DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDM-DECDLIRPCDDLVSC 185
D + C C+ + + C C +GY G C D+ DEC PC + +C
Sbjct: 1111 DVARLCQHGGLCVDAGNT--HHCR-CQAGY--TGSYCEDLVDECS-PSPCQNGATC 1160
Score = 56.8 bits (131), Expect = 3e-07
Identities = 86/349 (24%), Positives = 124/349 (35%), Gaps = 47/349 (13%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C +T G+RC G + +T C NPC G C D + + C C GF
Sbjct: 881 GASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGG-SCTDGINTAF-C-DCLPGF 937
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
G E C ++ C G +C + C +CP G+ G + + C
Sbjct: 938 RGTFCEEDINECASDPCRNGANCTDCVDSYTC-TCPAGFSGIHCENNTPDCTESSCFNGG 996
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C+ S + C CP G+ Y D++ECD +PC +C++
Sbjct: 997 TCVDGINS--FTCL-CPPGFT-GSYCQHDVNECD-SQPCLHGGTCQD-------GCGSYR 1044
Query: 201 XXXSQGWRGTGNERRREHCVDVDECADG----------RANCPRG--RLCVNTPQYPSNP 248
QG+ G N + H D C +G R CP G L + P
Sbjct: 1045 CTCPQGYTGP-NCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEV 1103
Query: 249 VSSLQG---------SYICVPCGGHYYVNTTRPCFDP--DSLVKRCDPSYCRRFNAVCG- 296
+ QG +CV G ++ + LV C PS C+ A C
Sbjct: 1104 AAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQN-GATCTD 1162
Query: 297 --FGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQ-LPCNE-PRCKKDNCP 341
G C C G+ G +D L HP + C + P K +CP
Sbjct: 1163 YLGGYSCKCVAGYHGVNCSEEIDECL-SHPCQNGGTCLDLPNTYKCSCP 1210
Score = 48.8 bits (111), Expect = 8e-05
Identities = 83/334 (24%), Positives = 123/334 (36%), Gaps = 52/334 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCF-GGRVPCQDLPDGRYQCGKCPSGFHG 82
C+D F+C PG + + C+++PC GR C D + +QC +CP+GF G
Sbjct: 467 CLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGR--CLDKIN-EFQC-ECPTGFTG 522
Query: 83 NGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQKPCGRERR 141
+ + C + C G C + C C GY G + CD PC
Sbjct: 523 HLCQYDVDECASTPCKNGAKCLDGPNTYTC-VCTEGYTGTHCEVDIDECDPD-PC-HYGS 579
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C K + C C GY G+ C +++EC +PC +C++ +
Sbjct: 580 C--KDGVATFTCL-CRPGY--TGHHCETNINECS-SQPCRHGGTCQDRDNAYLCFCL--- 630
Query: 201 XXXSQGWRGTGNERRREHCV----DVDECADG----RANCP---RGRLC-VNTPQYPSNP 248
+G G E + C D C D C G +C +N + NP
Sbjct: 631 ----KGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNP 686
Query: 249 VSSLQGSYICVPCGGHYYVNTTRPCFDPDSL--VKRCDPSYCRRFNAVCG---FGQKCVC 303
C + DP L V C+ + C + C G KC C
Sbjct: 687 ---CHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPC--VHGACRDSLNGYKCDC 741
Query: 304 NTGWTGNGTVCGLDRDLDGHPDEQLPC-NEPRCK 336
+ GW +GT C D++ + E PC N CK
Sbjct: 742 DPGW--SGTNC----DINNNECESNPCVNGGTCK 769
Score = 47.2 bits (107), Expect = 2e-04
Identities = 43/168 (25%), Positives = 65/168 (38%), Gaps = 13/168 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G +C+D + C G + + C +PC G C+D + C C G+
Sbjct: 540 GAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG--SCKD-GVATFTC-LCRPGY 595
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
G+ E C + C G +C++ C C G G + A PC
Sbjct: 596 TGHHCETNINECSSQPCRHGGTCQDRDNAYLC-FCLKGTTGPNCEINLDDCASSPCD-SG 653
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C+ K YEC C GY G C +++DEC PC + +C +
Sbjct: 654 TCLDKIDG--YEC-ACEPGY--TGSMCNINIDEC-AGNPCHNGGTCED 695
Score = 46.4 bits (105), Expect = 4e-04
Identities = 50/161 (31%), Positives = 65/161 (40%), Gaps = 33/161 (20%)
Query: 31 FRCERCPGSQTSDGQTCRTA--CSANPCFGGRVPCQDLP-DGRYQCGKCPSGFHG----- 82
++C RCP + G++C+ A C++NPC G Q LP + Y C CP FHG
Sbjct: 125 YKC-RCPPGWS--GKSCQQADPCASNPCANGG---QCLPFEASYIC-HCPPSFHGPTCRQ 177
Query: 83 NGVECYRIS--CR-ANTCFQGVS-----CEETQYGPKCG----SCPTGYVGDGRQCQHVC 130
+ EC + CR TC V C T GP C C +G C+
Sbjct: 178 DVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTG 237
Query: 131 DAQKPCGRERRCMPKSTSPYYE--CEGCPSGYQWNGYTCVD 169
D C C+P T E + CP NG CVD
Sbjct: 238 DVTHECA----CLPGFTGQNCEENIDDCPGNNCKNGGACVD 274
Score = 45.6 bits (103), Expect = 7e-04
Identities = 43/148 (29%), Positives = 58/148 (39%), Gaps = 20/148 (13%)
Query: 35 RCPGSQTSDGQTCR---TACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS 91
RC T G C CS +PC G C+ D ++C C GF G E
Sbjct: 203 RCVCRATHTGPNCERPYVPCSPSPCQNGGT-CRPTGDVTHECA-CLPGFTGQNCEENIDD 260
Query: 92 CRANTCFQGVSCEETQYGPKCGSCPTGYVG-----DGRQCQHVCDAQKPCGRERRCMPKS 146
C N C G +C + C CP + G D +CQ + +A C C +
Sbjct: 261 CPGNNCKNGGACVDGVNTYNC-RCPPEWTGQYCTEDVDECQLMPNA---CQNGGTC--HN 314
Query: 147 TSPYYECEGCPSGYQWNGYTCVD-MDEC 173
T Y C C +G W G C + +D+C
Sbjct: 315 THGGYNCV-CVNG--WTGEDCSENIDDC 339
Score = 43.2 bits (97), Expect = 0.004
Identities = 51/172 (29%), Positives = 74/172 (43%), Gaps = 25/172 (14%)
Query: 21 GERCVDTDQGFRCERCP-GSQTSDGQTCRTAC-------SANP-CFGGRVPCQDLPDGRY 71
G C+D ++C CP G+Q + C S +P CF C D G Y
Sbjct: 1195 GGTCLDLPNTYKCS-CPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGT-CVDQVGG-Y 1251
Query: 72 QCGKCPSGFHGNGVECYRISCRANTC-FQGV-SCEETQYGPKCGSCPTGYVGDGRQCQHV 129
C CP GF G E C +N C +G +C + C C G+ GR+C+ V
Sbjct: 1252 SC-TCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHC-ECRAGHT--GRRCESV 1307
Query: 130 CDA--QKPCGRERRC-MPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIR 177
+ KPC C + +T+ + C+ CP+G++ G TC D C +R
Sbjct: 1308 INGCKGKPCKNGGTCAVASNTARGFICK-CPAGFE--GATCENDARTCGSLR 1356
>AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein
variant protein.
Length = 2067
Score = 85.8 bits (203), Expect = 5e-16
Identities = 53/170 (31%), Positives = 75/170 (44%), Gaps = 9/170 (5%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
CV C D+ G++C+ PG ++ C +NPC G C+D+ G Y C C
Sbjct: 237 CVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGT-CKDMTSG-YVC-TCRE 293
Query: 79 GFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGR 138
GF G + C +N C +C + G KC +C Y G + A PC
Sbjct: 294 GFSGPNCQTNINECASNPCLNQGTCIDDVAGYKC-NCLLPYTGATCEVVLAPCAPSPCRN 352
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C + C CP+G W G TC VD++EC ++ PC SC+N
Sbjct: 353 GGECRQSEDYESFSCV-CPTG--WQGQTCEVDINEC-VLSPCRHGASCQN 398
Score = 63.3 bits (147), Expect = 3e-09
Identities = 46/155 (29%), Positives = 60/155 (38%), Gaps = 12/155 (7%)
Query: 22 ERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPS 78
+ CV F CE C T G+ C + C PC G R KCP+
Sbjct: 794 QNCVQRVNDFHCE-CRAGHT--GRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPA 850
Query: 79 GFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQ--CQHVCDAQKPC 136
GF G E +C + C G +C P C C + G Q C PC
Sbjct: 851 GFEGATCENDARTCGSLRCLNGGTCISGPRSPTC-LCLGPFTGPECQFPASSPCLGGNPC 909
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMD 171
+ C P S SP+Y C CP+ ++NG C +D
Sbjct: 910 YNQGTCEPTSESPFYRCL-CPA--KFNGLLCHILD 941
Score = 60.9 bits (141), Expect = 2e-08
Identities = 77/303 (25%), Positives = 109/303 (35%), Gaps = 34/303 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C+D G++C C T G TC C+ +PC G C+ D CP+G+
Sbjct: 318 CIDDVAGYKCN-CLLPYT--GATCEVVLAPCAPSPCRNGG-ECRQSEDYESFSCVCPTGW 373
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C + C G SC+ T G +C C GY GR C+ D PC
Sbjct: 374 QGQTCEVDINECVLSPCRHGASCQNTHGGYRC-HCQAGY--SGRNCETDIDDCRPNPCHN 430
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXX 197
C + + C+ C G++ G C D++EC PC + +C +
Sbjct: 431 GGSCTDGINTAF--CD-CLPGFR--GTFCEEDINEC-ASDPCRNGANC--TDCVDSYTCT 482
Query: 198 XXXXXXSQGWRGTGNERRREHCVDVDECADG----RANCPRGRLCVNTPQYPSNPVSS-- 251
+ C + C DG CP G + Q+ N S
Sbjct: 483 CPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPG-FTGSYCQHDVNECDSQP 541
Query: 252 -LQGSYICVPCGGHYYVNTTRPCFDPD--SLVKRCDPSYCRRFNAV--CGFGQKCVCNTG 306
L G C G Y + P+ +LV CD S C+ +C C +G
Sbjct: 542 CLHGG-TCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSG 600
Query: 307 WTG 309
WTG
Sbjct: 601 WTG 603
Score = 59.3 bits (137), Expect = 5e-08
Identities = 88/317 (27%), Positives = 116/317 (36%), Gaps = 50/317 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C D F C PG +T CS+ PC G CQD D Y C C G G
Sbjct: 92 CKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGT-CQDR-DNAYLCF-CLKGTTGP 148
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
E C ++ C G +C + G +C +C GY G C D A PC
Sbjct: 149 NCEINLDDCASSPCDSG-TCLDKIDGYEC-ACEPGYTGS--MCNINIDECAGNPCHNGGT 204
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C + C CP GY + TC+ +++EC+ PC +CR+
Sbjct: 205 CEDGING--FTCR-CPEGY--HDPTCLSEVNECNS-NPCVH-GACRDS-------LNGYK 250
Query: 201 XXXSQGWRGTG-----NERRREHCVDVDECADGRAN----CPRG----RLCVNTPQYPSN 247
GW GT NE CV+ C D + C G N + SN
Sbjct: 251 CDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASN 310
Query: 248 PVSSLQGSYICVPCGGHYYVNTTRPCFDP--DSLVKRCDPSYCRRFNAVCGFGQ-----K 300
P + QG+ C+ Y N P + ++ C PS CR C +
Sbjct: 311 PCLN-QGT--CIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRN-GGECRQSEDYESFS 366
Query: 301 CVCNTGWTGNGTVCGLD 317
CVC TGW G C +D
Sbjct: 367 CVCPTGW--QGQTCEVD 381
Score = 58.4 bits (135), Expect = 9e-08
Identities = 48/169 (28%), Positives = 74/169 (43%), Gaps = 15/169 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D D + C G+ + + C+++PC G C D DG Y+C C G+
Sbjct: 127 GGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGT--CLDKIDG-YECA-CEPGY 182
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA-QKPCGRE 139
G+ C N C G +CE+ G C CP GY D V + PC
Sbjct: 183 TGSMCNINIDECAGNPCHNGGTCEDGINGFTC-RCPEGY-HDPTCLSEVNECNSNPC-VH 239
Query: 140 RRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C + + Y+C+ C G W+G C ++ +EC+ PC + +C++
Sbjct: 240 GAC--RDSLNGYKCD-CDPG--WSGTNCDINNNECE-SNPCVNGGTCKD 282
Score = 58.0 bits (134), Expect = 1e-07
Identities = 51/176 (28%), Positives = 70/176 (39%), Gaps = 21/176 (11%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G CVD F C PG S Q C + PC G CQD G Y+C CP G+
Sbjct: 507 GGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGT-CQD-GCGSYRC-TCPQGY 563
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-----DGRQCQHVC----- 130
G + C ++ C G C +T +C CP+G+ G C+
Sbjct: 564 TGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRC-ECPSGWTGLYCDVPSVSCEVAAQRQGV 622
Query: 131 DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDM-DECDLIRPCDDLVSC 185
D + C C+ + + C C +GY G C D+ DEC PC + +C
Sbjct: 623 DVARLCQHGGLCVDAGNT--HHCR-CQAGY--TGSYCEDLVDECS-PSPCQNGATC 672
Score = 56.8 bits (131), Expect = 3e-07
Identities = 86/349 (24%), Positives = 124/349 (35%), Gaps = 47/349 (13%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C +T G+RC G + +T C NPC G C D + + C C GF
Sbjct: 393 GASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGG-SCTDGINTAF-C-DCLPGF 449
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
G E C ++ C G +C + C +CP G+ G + + C
Sbjct: 450 RGTFCEEDINECASDPCRNGANCTDCVDSYTC-TCPAGFSGIHCENNTPDCTESSCFNGG 508
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C+ S + C CP G+ Y D++ECD +PC +C++
Sbjct: 509 TCVDGINS--FTCL-CPPGFT-GSYCQHDVNECD-SQPCLHGGTCQD-------GCGSYR 556
Query: 201 XXXSQGWRGTGNERRREHCVDVDECADG----------RANCPRG--RLCVNTPQYPSNP 248
QG+ G N + H D C +G R CP G L + P
Sbjct: 557 CTCPQGYTGP-NCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEV 615
Query: 249 VSSLQG---------SYICVPCGGHYYVNTTRPCFDP--DSLVKRCDPSYCRRFNAVCG- 296
+ QG +CV G ++ + LV C PS C+ A C
Sbjct: 616 AAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQN-GATCTD 674
Query: 297 --FGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQ-LPCNE-PRCKKDNCP 341
G C C G+ G +D L HP + C + P K +CP
Sbjct: 675 YLGGYSCKCVAGYHGVNCSEEIDECL-SHPCQNGGTCLDLPNTYKCSCP 722
Score = 47.2 bits (107), Expect = 2e-04
Identities = 43/168 (25%), Positives = 65/168 (38%), Gaps = 13/168 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G +C+D + C G + + C +PC G C+D + C C G+
Sbjct: 52 GAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG--SCKD-GVATFTC-LCRPGY 107
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
G+ E C + C G +C++ C C G G + A PC
Sbjct: 108 TGHHCETNINECSSQPCRHGGTCQDRDNAYLC-FCLKGTTGPNCEINLDDCASSPCD-SG 165
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C+ K YEC C GY G C +++DEC PC + +C +
Sbjct: 166 TCLDKIDG--YEC-ACEPGY--TGSMCNINIDEC-AGNPCHNGGTCED 207
Score = 43.2 bits (97), Expect = 0.004
Identities = 51/172 (29%), Positives = 74/172 (43%), Gaps = 25/172 (14%)
Query: 21 GERCVDTDQGFRCERCP-GSQTSDGQTCRTAC-------SANP-CFGGRVPCQDLPDGRY 71
G C+D ++C CP G+Q + C S +P CF C D G Y
Sbjct: 707 GGTCLDLPNTYKCS-CPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGT-CVDQVGG-Y 763
Query: 72 QCGKCPSGFHGNGVECYRISCRANTC-FQGV-SCEETQYGPKCGSCPTGYVGDGRQCQHV 129
C CP GF G E C +N C +G +C + C C G+ GR+C+ V
Sbjct: 764 SC-TCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHC-ECRAGHT--GRRCESV 819
Query: 130 CDA--QKPCGRERRC-MPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIR 177
+ KPC C + +T+ + C+ CP+G++ G TC D C +R
Sbjct: 820 INGCKGKPCKNGGTCAVASNTARGFICK-CPAGFE--GATCENDARTCGSLR 868
Score = 41.5 bits (93), Expect = 0.011
Identities = 77/307 (25%), Positives = 113/307 (36%), Gaps = 52/307 (16%)
Query: 51 CSANPCF-GGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYG 109
C+++PC GR C D + +QC +CP+GF G+ + C + C G C +
Sbjct: 6 CASSPCLHNGR--CLDKIN-EFQC-ECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNT 61
Query: 110 PKCGSCPTGYVGDGRQCQ-HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC- 167
C C GY G + CD PC C K + C C GY G+ C
Sbjct: 62 YTC-VCTEGYTGTHCEVDIDECDPD-PC-HYGSC--KDGVATFTCL-CRPGY--TGHHCE 113
Query: 168 VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCV----DVD 223
+++EC +PC +C++ + +G G E + C D
Sbjct: 114 TNINECS-SQPCRHGGTCQDRDNAYLCFCL-------KGTTGPNCEINLDDCASSPCDSG 165
Query: 224 ECADG----RANCP---RGRLC-VNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFD 275
C D C G +C +N + NP C + D
Sbjct: 166 TCLDKIDGYECACEPGYTGSMCNINIDECAGNP---CHNGGTCEDGINGFTCRCPEGYHD 222
Query: 276 PDSL--VKRCDPSYCRRFNAVCG---FGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQLPC 330
P L V C+ + C + C G KC C+ GW +GT C D++ + E PC
Sbjct: 223 PTCLSEVNECNSNPC--VHGACRDSLNGYKCDCDPGW--SGTNC----DINNNECESNPC 274
Query: 331 -NEPRCK 336
N CK
Sbjct: 275 VNGGTCK 281
>Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein.
Length = 1821
Score = 84.6 bits (200), Expect = 1e-15
Identities = 102/336 (30%), Positives = 134/336 (39%), Gaps = 55/336 (16%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRT---ACSANPCFG-GRVPCQDLPDGRYQC 73
+C CV+ G+RC PG Q Q T C +PC G GR C + G Y C
Sbjct: 855 VCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCQGKGR--CINRV-GSYSC 911
Query: 74 GKCPSGF----HGNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGYVGDGR-QCQ 127
C G+ G EC I+ C G C T+ C C GY+ + CQ
Sbjct: 912 F-CYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHC-ECDQGYIMVRKGHCQ 969
Query: 128 HVCDAQKP--CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSC 185
+ + + P C + RC+ S Y C C GY+ +CVD++EC C C
Sbjct: 970 DINECRHPGTCP-DGRCVNSPGS--YTCLACEEGYRGQSGSCVDVNECLTPGVCAH-GKC 1025
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N E QG+ T +E+ C DVDECA RA+CP G LC+NT
Sbjct: 1026 TNLE-------GSFRCSCEQGYEVTSDEK---GCQDVDECA-SRASCPTG-LCLNT---- 1069
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTT-RPCFDPD--SLVKRCDPSYCRRFNAVCGFGQKCV 302
+GS+ C C Y+VN C D D + C C N F K
Sbjct: 1070 -------EGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCT--NTAGSFSCK-D 1119
Query: 303 CNTGWTGN--GTVCGLDRDLDGHPDEQLPCNEPRCK 336
C+ G+ + G C D+D D Q C CK
Sbjct: 1120 CDGGYRPSPLGDSC---EDVDECEDPQSSCLGGECK 1152
Score = 47.2 bits (107), Expect = 2e-04
Identities = 66/252 (26%), Positives = 89/252 (35%), Gaps = 36/252 (14%)
Query: 5 SMGDAGSMVTPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGR--V 61
S D P C+G C +T ++C CP G Q ++G C N C G
Sbjct: 1132 SCEDVDECEDPQSSCLGGECKNTVGSYQC-LCPQGFQLANGTVCE---DVNECMGEEHCA 1187
Query: 62 PCQDL--PDGRYQCGKCPSGFHG--NGVECYRI-SCRANTCFQGVSCEETQYGPKCGSCP 116
P + G + C C GF G C + C G C T+ C C
Sbjct: 1188 PHGECLNSHGSFFC-LCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNC-LCE 1245
Query: 117 TGY--VGDGRQCQHV--C-DAQKPCGRERRCMPKSTSPYYECE-GCPSGYQW--NGYTCV 168
TG+ + +C + C D P +C +++ Y C GC G+ NG C+
Sbjct: 1246 TGFQPSPESGECVDIDECEDYGDPVCGTWKC--ENSPGSYRCVLGCQPGFHMAPNG-DCI 1302
Query: 169 DMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADG 228
D+DEC C C N + GW CVDV+EC
Sbjct: 1303 DIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGW----------DCVDVNECELM 1352
Query: 229 RANCPRGRLCVN 240
A C LC N
Sbjct: 1353 LAVC-GAALCEN 1363
Score = 45.6 bits (103), Expect = 7e-04
Identities = 46/181 (25%), Positives = 76/181 (41%), Gaps = 22/181 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQT-CRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
C+++ F C PG +++G T C+ + +PC GG C + +G + C C +G
Sbjct: 1192 CLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGH--CVNT-EGSFNC-LCETG 1247
Query: 80 FHGN--GVECYRIS-CR--ANTCFQGVSCEETQYGPKC--GSCPTGYVGDGRQCQHV--C 130
F + EC I C + CE + +C G P ++ C + C
Sbjct: 1248 FQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDEC 1307
Query: 131 DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN--GYTCVDMDECDLIRPCDDLVSCRNE 188
CG C +T + C C G++ + G+ CVD++EC+L+ C N
Sbjct: 1308 ANDTMCGSHGFC--DNTDGSFRCL-CDQGFEISPSGWDCVDVNECELMLAVCGAALCENV 1364
Query: 189 E 189
E
Sbjct: 1365 E 1365
>S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growth
factor-beta-binding protein-2 protein.
Length = 1821
Score = 84.6 bits (200), Expect = 1e-15
Identities = 102/336 (30%), Positives = 134/336 (39%), Gaps = 55/336 (16%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRT---ACSANPCFG-GRVPCQDLPDGRYQC 73
+C CV+ G+RC PG Q Q T C +PC G GR C + G Y C
Sbjct: 855 VCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGR--CINRV-GSYSC 911
Query: 74 GKCPSGF----HGNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGYVGDGR-QCQ 127
C G+ G EC I+ C G C T+ C C GY+ + CQ
Sbjct: 912 F-CYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHC-ECDQGYIMVRKGHCQ 969
Query: 128 HVCDAQKP--CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSC 185
+ + + P C + RC+ S Y C C GY+ +CVD++EC C C
Sbjct: 970 DINECRHPGTCP-DGRCVNSPGS--YTCLACEEGYRGQSGSCVDVNECLTPGVCAH-GKC 1025
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N E QG+ T +E+ C DVDECA RA+CP G LC+NT
Sbjct: 1026 TNLE-------GSFRCSCEQGYEVTSDEK---GCQDVDECA-SRASCPTG-LCLNT---- 1069
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTT-RPCFDPD--SLVKRCDPSYCRRFNAVCGFGQKCV 302
+GS+ C C Y+VN C D D + C C N F K
Sbjct: 1070 -------EGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCT--NTAGSFSCK-D 1119
Query: 303 CNTGWTGN--GTVCGLDRDLDGHPDEQLPCNEPRCK 336
C+ G+ + G C D+D D Q C CK
Sbjct: 1120 CDGGYRPSPLGDSC---EDVDECEDPQSSCLGGECK 1152
Score = 47.2 bits (107), Expect = 2e-04
Identities = 66/252 (26%), Positives = 89/252 (35%), Gaps = 36/252 (14%)
Query: 5 SMGDAGSMVTPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGR--V 61
S D P C+G C +T ++C CP G Q ++G C N C G
Sbjct: 1132 SCEDVDECEDPQSSCLGGECKNTVGSYQC-LCPQGFQLANGTVCE---DVNECMGEEHCA 1187
Query: 62 PCQDL--PDGRYQCGKCPSGFHG--NGVECYRI-SCRANTCFQGVSCEETQYGPKCGSCP 116
P + G + C C GF G C + C G C T+ C C
Sbjct: 1188 PHGECLNSHGSFFC-LCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNC-LCE 1245
Query: 117 TGY--VGDGRQCQHV--C-DAQKPCGRERRCMPKSTSPYYECE-GCPSGYQW--NGYTCV 168
TG+ + +C + C D P +C +++ Y C GC G+ NG C+
Sbjct: 1246 TGFQPSPESGECVDIDECEDYGDPVCGTWKC--ENSPGSYRCVLGCQPGFHMAPNG-DCI 1302
Query: 169 DMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADG 228
D+DEC C C N + GW CVDV+EC
Sbjct: 1303 DIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGW----------DCVDVNECELM 1352
Query: 229 RANCPRGRLCVN 240
A C LC N
Sbjct: 1353 LAVC-GAALCEN 1363
Score = 45.6 bits (103), Expect = 7e-04
Identities = 46/181 (25%), Positives = 76/181 (41%), Gaps = 22/181 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQT-CRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
C+++ F C PG +++G T C+ + +PC GG C + +G + C C +G
Sbjct: 1192 CLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGH--CVNT-EGSFNC-LCETG 1247
Query: 80 FHGN--GVECYRIS-CR--ANTCFQGVSCEETQYGPKC--GSCPTGYVGDGRQCQHV--C 130
F + EC I C + CE + +C G P ++ C + C
Sbjct: 1248 FQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDEC 1307
Query: 131 DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN--GYTCVDMDECDLIRPCDDLVSCRNE 188
CG C +T + C C G++ + G+ CVD++EC+L+ C N
Sbjct: 1308 ANDTMCGSHGFC--DNTDGSFRCL-CDQGFEISPSGWDCVDVNECELMLAVCGAALCENV 1364
Query: 189 E 189
E
Sbjct: 1365 E 1365
>BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming growth
factor beta binding protein 2 protein.
Length = 1821
Score = 84.6 bits (200), Expect = 1e-15
Identities = 102/336 (30%), Positives = 134/336 (39%), Gaps = 55/336 (16%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRT---ACSANPCFG-GRVPCQDLPDGRYQC 73
+C CV+ G+RC PG Q Q T C +PC G GR C + G Y C
Sbjct: 855 VCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGR--CINRV-GSYSC 911
Query: 74 GKCPSGF----HGNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGYVGDGR-QCQ 127
C G+ G EC I+ C G C T+ C C GY+ + CQ
Sbjct: 912 F-CYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHC-ECDQGYIMVRKGHCQ 969
Query: 128 HVCDAQKP--CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSC 185
+ + + P C + RC+ S Y C C GY+ +CVD++EC C C
Sbjct: 970 DINECRHPGTCP-DGRCVNSPGS--YTCLACEEGYRGQSGSCVDVNECLTPGVCAH-GKC 1025
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N E QG+ T +E+ C DVDECA RA+CP G LC+NT
Sbjct: 1026 TNLE-------GSFRCSCEQGYEVTSDEK---GCQDVDECA-SRASCPTG-LCLNT---- 1069
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTT-RPCFDPD--SLVKRCDPSYCRRFNAVCGFGQKCV 302
+GS+ C C Y+VN C D D + C C N F K
Sbjct: 1070 -------EGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCT--NTAGSFSCK-D 1119
Query: 303 CNTGWTGN--GTVCGLDRDLDGHPDEQLPCNEPRCK 336
C+ G+ + G C D+D D Q C CK
Sbjct: 1120 CDGGYRPSPLGDSC---EDVDECEDPQSSCLGGECK 1152
Score = 47.2 bits (107), Expect = 2e-04
Identities = 66/252 (26%), Positives = 89/252 (35%), Gaps = 36/252 (14%)
Query: 5 SMGDAGSMVTPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGR--V 61
S D P C+G C +T ++C CP G Q ++G C N C G
Sbjct: 1132 SCEDVDECEDPQSSCLGGECKNTVGSYQC-LCPQGFQLANGTVCE---DVNECMGEEHCA 1187
Query: 62 PCQDL--PDGRYQCGKCPSGFHG--NGVECYRI-SCRANTCFQGVSCEETQYGPKCGSCP 116
P + G + C C GF G C + C G C T+ C C
Sbjct: 1188 PHGECLNSHGSFFC-LCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNC-LCE 1245
Query: 117 TGY--VGDGRQCQHV--C-DAQKPCGRERRCMPKSTSPYYECE-GCPSGYQW--NGYTCV 168
TG+ + +C + C D P +C +++ Y C GC G+ NG C+
Sbjct: 1246 TGFQPSPESGECVDIDECEDYGDPVCGTWKC--ENSPGSYRCVLGCQPGFHMAPNG-DCI 1302
Query: 169 DMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADG 228
D+DEC C C N + GW CVDV+EC
Sbjct: 1303 DIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGW----------DCVDVNECELM 1352
Query: 229 RANCPRGRLCVN 240
A C LC N
Sbjct: 1353 LAVC-GAALCEN 1363
Score = 45.6 bits (103), Expect = 7e-04
Identities = 46/181 (25%), Positives = 76/181 (41%), Gaps = 22/181 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQT-CRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
C+++ F C PG +++G T C+ + +PC GG C + +G + C C +G
Sbjct: 1192 CLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGH--CVNT-EGSFNC-LCETG 1247
Query: 80 FHGN--GVECYRIS-CR--ANTCFQGVSCEETQYGPKC--GSCPTGYVGDGRQCQHV--C 130
F + EC I C + CE + +C G P ++ C + C
Sbjct: 1248 FQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDEC 1307
Query: 131 DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN--GYTCVDMDECDLIRPCDDLVSCRNE 188
CG C +T + C C G++ + G+ CVD++EC+L+ C N
Sbjct: 1308 ANDTMCGSHGFC--DNTDGSFRCL-CDQGFEISPSGWDCVDVNECELMLAVCGAALCENV 1364
Query: 189 E 189
E
Sbjct: 1365 E 1365
>AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming growth
factor beta binding protein 2 variant protein.
Length = 1700
Score = 84.6 bits (200), Expect = 1e-15
Identities = 102/336 (30%), Positives = 134/336 (39%), Gaps = 55/336 (16%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRT---ACSANPCFG-GRVPCQDLPDGRYQC 73
+C CV+ G+RC PG Q Q T C +PC G GR C + G Y C
Sbjct: 734 VCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGR--CINRV-GSYSC 790
Query: 74 GKCPSGF----HGNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGYVGDGR-QCQ 127
C G+ G EC I+ C G C T+ C C GY+ + CQ
Sbjct: 791 F-CYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHC-ECDQGYIMVRKGHCQ 848
Query: 128 HVCDAQKP--CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSC 185
+ + + P C + RC+ S Y C C GY+ +CVD++EC C C
Sbjct: 849 DINECRHPGTCP-DGRCVNSPGS--YTCLACEEGYRGQSGSCVDVNECLTPGVCAH-GKC 904
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N E QG+ T +E+ C DVDECA RA+CP G LC+NT
Sbjct: 905 TNLE-------GSFRCSCEQGYEVTSDEK---GCQDVDECA-SRASCPTG-LCLNT---- 948
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTT-RPCFDPD--SLVKRCDPSYCRRFNAVCGFGQKCV 302
+GS+ C C Y+VN C D D + C C N F K
Sbjct: 949 -------EGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCT--NTAGSFSCK-D 998
Query: 303 CNTGWTGN--GTVCGLDRDLDGHPDEQLPCNEPRCK 336
C+ G+ + G C D+D D Q C CK
Sbjct: 999 CDGGYRPSPLGDSC---EDVDECEDPQSSCLGGECK 1031
Score = 47.2 bits (107), Expect = 2e-04
Identities = 66/252 (26%), Positives = 89/252 (35%), Gaps = 36/252 (14%)
Query: 5 SMGDAGSMVTPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGR--V 61
S D P C+G C +T ++C CP G Q ++G C N C G
Sbjct: 1011 SCEDVDECEDPQSSCLGGECKNTVGSYQC-LCPQGFQLANGTVCE---DVNECMGEEHCA 1066
Query: 62 PCQDL--PDGRYQCGKCPSGFHG--NGVECYRI-SCRANTCFQGVSCEETQYGPKCGSCP 116
P + G + C C GF G C + C G C T+ C C
Sbjct: 1067 PHGECLNSHGSFFC-LCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNC-LCE 1124
Query: 117 TGY--VGDGRQCQHV--C-DAQKPCGRERRCMPKSTSPYYECE-GCPSGYQW--NGYTCV 168
TG+ + +C + C D P +C +++ Y C GC G+ NG C+
Sbjct: 1125 TGFQPSPESGECVDIDECEDYGDPVCGTWKC--ENSPGSYRCVLGCQPGFHMAPNG-DCI 1181
Query: 169 DMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADG 228
D+DEC C C N + GW CVDV+EC
Sbjct: 1182 DIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGW----------DCVDVNECELM 1231
Query: 229 RANCPRGRLCVN 240
A C LC N
Sbjct: 1232 LAVC-GAALCEN 1242
Score = 45.6 bits (103), Expect = 7e-04
Identities = 46/181 (25%), Positives = 76/181 (41%), Gaps = 22/181 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQT-CRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
C+++ F C PG +++G T C+ + +PC GG C + +G + C C +G
Sbjct: 1071 CLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGH--CVNT-EGSFNC-LCETG 1126
Query: 80 FHGN--GVECYRIS-CR--ANTCFQGVSCEETQYGPKC--GSCPTGYVGDGRQCQHV--C 130
F + EC I C + CE + +C G P ++ C + C
Sbjct: 1127 FQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDEC 1186
Query: 131 DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN--GYTCVDMDECDLIRPCDDLVSCRNE 188
CG C +T + C C G++ + G+ CVD++EC+L+ C N
Sbjct: 1187 ANDTMCGSHGFC--DNTDGSFRCL-CDQGFEISPSGWDCVDVNECELMLAVCGAALCENV 1243
Query: 189 E 189
E
Sbjct: 1244 E 1244
>U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.
Length = 2003
Score = 83.4 bits (197), Expect = 3e-15
Identities = 77/256 (30%), Positives = 105/256 (41%), Gaps = 28/256 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C + G+ C CP S T G C+T+ C + PCF G C + P G + C C
Sbjct: 741 GGSCNPSPGGYYCT-CPPSHT--GPQCQTSTDYCVSAPCFNGGT-CVNRP-GTFSC-LCA 794
Query: 78 SGFHGNGVEC-YRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQK 134
GF G E R SC + C +C+++ GP+C CPTGY G CQ + D AQK
Sbjct: 795 MGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC-LCPTGYTGG--SCQTLMDLCAQK 851
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECD--LIRPCDDLVSCRNEEXX 191
PC R C+ T P + C C G W G C + + C + D+ S +
Sbjct: 852 PCPRNSHCL--QTGPSFHCL-CLQG--WTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGL 906
Query: 192 XXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC---PRGRLCVNTPQYPSNP 248
G++G+ + C + C +G A C P G LC P Y
Sbjct: 907 CVDSGPSYFCHCPPGFQGSLCQDHVNPC-ESRPCQNG-ATCMAQPSGYLCQCAPGYDGQN 964
Query: 249 VSSLQGSYICVPCGGH 264
S + PC H
Sbjct: 965 CSKELDACQSQPCHNH 980
Score = 57.2 bits (132), Expect = 2e-07
Identities = 47/168 (27%), Positives = 67/168 (39%), Gaps = 15/168 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C++T F C PG S + C + PC G C DL + C CP G
Sbjct: 449 GGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGST-CLDLL-ATFHC-LCPPGL 505
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C + C C + G +C C G+ G +C+ D PC
Sbjct: 506 EGQLCEVETNECASAPCLNHADCHDLLNGFQC-ICLPGF--SGTRCEEDIDECRSSPCAN 562
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSC 185
+C + + + C+ C G++ G C ++DEC L PC SC
Sbjct: 563 GGQCQDQPGA--FHCK-CLPGFE--GPRCQTEVDEC-LSDPCPVGASC 604
Score = 56.8 bits (131), Expect = 3e-07
Identities = 79/285 (27%), Positives = 108/285 (37%), Gaps = 46/285 (16%)
Query: 32 RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS 91
+C PG T + R CSANPC G V P + QC CP GF G+ E
Sbjct: 142 QCSCMPG-WTGEQCQLRDFCSANPCVNGGVCLATYP--QIQC-HCPPGFEGHACERDVNE 197
Query: 92 C--RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRC--MPKST 147
C C +G SC T +C CP G G + + + C C MP+
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKD 256
Query: 148 SPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQG 206
S ++ C CP G+ G C V+ D C + C + +C++ +
Sbjct: 257 STFHLCL-CPPGF--IGPDCEVNPDNC-VSHQCQNGGTCQD-------GLDTYTCLCPET 305
Query: 207 WRGTGNERRREHCVDVDEC-ADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHY 265
W G + DVDEC G +C G C N+ GS+ CV C +
Sbjct: 306 WTGW------DCSEDVDECETQGPPHCRNGGTCQNS-----------AGSFHCV-CVSGW 347
Query: 266 YVNTTRPCFDPDSLVKRCDP-SYCRRFNAVCGFGQKCVCNTGWTG 309
+ D D + C P S C + V F C+C G TG
Sbjct: 348 GGTSCEENLD-DCIAATCAPGSTC--IDRVGSF--SCLCPPGRTG 387
Score = 56.0 bits (129), Expect = 5e-07
Identities = 39/112 (34%), Positives = 50/112 (44%), Gaps = 13/112 (11%)
Query: 71 YQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVC 130
Y C CP GF G+ + + C + C G +C G C C GY DG+ C
Sbjct: 914 YFC-HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLC-QCAPGY--DGQNCSKEL 969
Query: 131 DA--QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPC 179
DA +PC C PK + C CP G+ G C D+DEC L +PC
Sbjct: 970 DACQSQPCHNHGTCTPKPGG--FHC-ACPPGFV--GLRCEGDVDEC-LDQPC 1015
Score = 53.6 bits (123), Expect = 3e-06
Identities = 60/194 (30%), Positives = 74/194 (38%), Gaps = 41/194 (21%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G +C D F C+ PG + QT C ++PC G C DLP G + C CPSGF
Sbjct: 563 GGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVG-ASCLDLP-GAFFC-LCPSGF 619
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-----DGRQCQH------- 128
G C C N C C++ + C CP G G D C H
Sbjct: 620 --TGQLCEVPLCAPNLCQPKQICKDQKDKANC-LCPDGSPGCAPPEDNCTCHHGHCQRSS 676
Query: 129 -VCDA---------------QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMD 171
VCD PC C P+ + Y C CP+GY G TC +M
Sbjct: 677 CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG--YNCT-CPTGY--TGPTCSEEMT 731
Query: 172 ECDLIRPCDDLVSC 185
C PC + SC
Sbjct: 732 ACH-SGPCLNGGSC 744
Score = 50.4 bits (115), Expect = 2e-05
Identities = 46/160 (28%), Positives = 65/160 (40%), Gaps = 15/160 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA-CSANPCFGGRVPCQDLP--DGRYQCGKCP 77
G C +T F+C CP Q R C C G CQ +P D + CP
Sbjct: 208 GTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGT-CQLMPEKDSTFHLCLCP 265
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-DGRQCQHVCDAQKP- 135
GF G E +C ++ C G +C++ C CP + G D + C+ Q P
Sbjct: 266 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTC-LCPETWTGWDCSEDVDECETQGPP 324
Query: 136 -CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDEC 173
C C + S + C C SG W G +C + +D+C
Sbjct: 325 HCRNGGTCQNSAGS--FHCV-CVSG--WGGTSCEENLDDC 359
Score = 49.6 bits (113), Expect = 4e-05
Identities = 53/177 (29%), Positives = 73/177 (41%), Gaps = 20/177 (11%)
Query: 21 GERCVDTDQGFRCERCPGSQTS-----DGQTCRTACSANPCFGGRVPCQDLPDGRYQCGK 75
G C D + C CP + T D C T + GG CQ+ G + C
Sbjct: 288 GGTCQDGLDTYTC-LCPETWTGWDCSEDVDECETQGPPHCRNGGT--CQNSA-GSFHC-V 342
Query: 76 CPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
C SG+ G E C A TC G +C + C CP G G + +C +Q P
Sbjct: 343 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSC-LCPPGRTGLLCHLEDMCLSQ-P 400
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIR----PCDDLVSCRN 187
C + +C ST+P C ++G TC D+DEC + + PC+ SC N
Sbjct: 401 CHGDAQC---STNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLN 454
Score = 47.2 bits (107), Expect = 2e-04
Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 11/113 (9%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGP 110
C + PC G C P G Y C CP+G+ G +C + C G SC + G
Sbjct: 695 CISAPCAHGGT-CYPQPSG-YNC-TCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGY 751
Query: 111 KCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQ 161
C +CP + G QCQ D PC C+ + + + C C G+Q
Sbjct: 752 YC-TCPPSHTGP--QCQTSTDYCVSAPCFNGGTCVNRPGT--FSCL-CAMGFQ 798
Score = 45.6 bits (103), Expect = 7e-04
Identities = 48/182 (26%), Positives = 69/182 (37%), Gaps = 16/182 (8%)
Query: 14 TPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGRVPCQDLPDG--- 69
T L +G+ GF E C + Q C+ S + P
Sbjct: 40 TCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTP 99
Query: 70 RYQCGKCPSGFHGNGVEC-YRISCRANTCFQGVSCEETQYG-PKCGSCPTGYVGDGRQCQ 127
+ C C GF G + C + C + C G P+C SC G+ G+ Q +
Sbjct: 100 SFLC-TCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQC-SCMPGWTGEQCQLR 157
Query: 128 HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDEC-DLIRPCDDLVSC 185
C A PC C+ +T P +C CP G++ G+ C D++EC PC SC
Sbjct: 158 DFCSA-NPCVNGGVCL--ATYPQIQCH-CPPGFE--GHACERDVNECFQDPGPCPKGTSC 211
Query: 186 RN 187
N
Sbjct: 212 HN 213
Score = 44.8 bits (101), Expect = 0.001
Identities = 39/142 (27%), Positives = 49/142 (34%), Gaps = 9/142 (6%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFG-GRVPCQDLPDGRYQCGKCPSGFHG 82
C GF C PG + C PC G C L + Y C +C G G
Sbjct: 983 CTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFY-C-QCLPGHTG 1040
Query: 83 NGVECYRISCRANTCFQGVSCEETQYGPK--CGSCPTGYVGDGRQCQHVCDA--QKPCGR 138
E C + CF G +CE T P CP G+ +G C H + C
Sbjct: 1041 QWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGF--EGPTCSHRAPSCGFHHCHH 1098
Query: 139 ERRCMPKSTSPYYECEGCPSGY 160
C+P + C SGY
Sbjct: 1099 GGLCLPSPKPGFPPRCACLSGY 1120
>U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.
Length = 1999
Score = 83.4 bits (197), Expect = 3e-15
Identities = 77/256 (30%), Positives = 105/256 (41%), Gaps = 28/256 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C + G+ C CP S T G C+T+ C + PCF G C + P G + C C
Sbjct: 740 GGSCNPSPGGYYCT-CPPSHT--GPQCQTSTDYCVSAPCFNGGT-CVNRP-GTFSC-LCA 793
Query: 78 SGFHGNGVEC-YRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQK 134
GF G E R SC + C +C+++ GP+C CPTGY G CQ + D AQK
Sbjct: 794 MGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC-LCPTGYTGG--SCQTLMDLCAQK 850
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECD--LIRPCDDLVSCRNEEXX 191
PC R C+ T P + C C G W G C + + C + D+ S +
Sbjct: 851 PCPRNSHCL--QTGPSFHCL-CLQG--WTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGL 905
Query: 192 XXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC---PRGRLCVNTPQYPSNP 248
G++G+ + C + C +G A C P G LC P Y
Sbjct: 906 CVDSGPSYFCHCPPGFQGSLCQDHVNPC-ESRPCQNG-ATCMAQPSGYLCQCAPGYDGQN 963
Query: 249 VSSLQGSYICVPCGGH 264
S + PC H
Sbjct: 964 CSKELDACQSQPCHNH 979
Score = 58.8 bits (136), Expect = 7e-08
Identities = 79/284 (27%), Positives = 108/284 (38%), Gaps = 44/284 (15%)
Query: 32 RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS 91
+C PG T + R CSANPC G V P + QC CP GF G+ E
Sbjct: 141 QCSCMPG-WTGEQCQLRDFCSANPCVNGGVCLATYP--QIQC-HCPPGFEGHACERDVNE 196
Query: 92 C--RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRC--MPKST 147
C C +G SC T +C CP G G + + + C C MP+
Sbjct: 197 CFQDPGPCPKGTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKD 255
Query: 148 SPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGW 207
S ++ C CP G+ G V+ D C + C + +C++ + W
Sbjct: 256 STFHLCL-CPPGFIGPGCE-VNPDNC-VSHQCQNGGTCQD-------GLDTYTCLCPETW 305
Query: 208 RGTGNERRREHCVDVDEC-ADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYY 266
G + DVDEC A G +C G C N+ GS+ CV C +
Sbjct: 306 TGW------DCSEDVDECEAQGPPHCRNGGTCQNS-----------AGSFHCV-CVSGWG 347
Query: 267 VNTTRPCFDPDSLVKRCDP-SYCRRFNAVCGFGQKCVCNTGWTG 309
+ D D + C P S C + V F C+C G TG
Sbjct: 348 GTSCEENLD-DCIAATCAPGSTC--IDRVGSF--SCLCPPGRTG 386
Score = 57.2 bits (132), Expect = 2e-07
Identities = 47/168 (27%), Positives = 67/168 (39%), Gaps = 15/168 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C++T F C PG S + C + PC G C DL + C CP G
Sbjct: 448 GGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGST-CLDLL-ATFHC-LCPPGL 504
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C + C C + G +C C G+ G +C+ D PC
Sbjct: 505 EGQLCEVETNECASAPCLNHADCHDLLNGFQC-ICLPGF--SGTRCEEDIDECRSSPCAN 561
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSC 185
+C + + + C+ C G++ G C ++DEC L PC SC
Sbjct: 562 GGQCQDQPGA--FHCK-CLPGFE--GPRCQTEVDEC-LSDPCPVGASC 603
Score = 56.0 bits (129), Expect = 5e-07
Identities = 39/112 (34%), Positives = 50/112 (44%), Gaps = 13/112 (11%)
Query: 71 YQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVC 130
Y C CP GF G+ + + C + C G +C G C C GY DG+ C
Sbjct: 913 YFC-HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLC-QCAPGY--DGQNCSKEL 968
Query: 131 DA--QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPC 179
DA +PC C PK + C CP G+ G C D+DEC L +PC
Sbjct: 969 DACQSQPCHNHGTCTPKPGG--FHC-ACPPGFV--GLRCEGDVDEC-LDQPC 1014
Score = 54.8 bits (126), Expect = 1e-06
Identities = 48/160 (30%), Positives = 67/160 (41%), Gaps = 15/160 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA-CSANPCFGGRVPCQDLP--DGRYQCGKCP 77
G C +T F+C CP Q R C C G CQ +P D + CP
Sbjct: 207 GTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGT-CQLMPEKDSTFHLCLCP 264
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-DGRQCQHVCDAQKP- 135
GF G G E +C ++ C G +C++ C CP + G D + C+AQ P
Sbjct: 265 PGFIGPGCEVNPDNCVSHQCQNGGTCQDGLDTYTC-LCPETWTGWDCSEDVDECEAQGPP 323
Query: 136 -CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDEC 173
C C + S + C C SG W G +C + +D+C
Sbjct: 324 HCRNGGTCQNSAGS--FHCV-CVSG--WGGTSCEENLDDC 358
Score = 53.6 bits (123), Expect = 3e-06
Identities = 60/194 (30%), Positives = 74/194 (38%), Gaps = 41/194 (21%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G +C D F C+ PG + QT C ++PC G C DLP G + C CPSGF
Sbjct: 562 GGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVG-ASCLDLP-GAFFC-LCPSGF 618
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-----DGRQCQH------- 128
G C C N C C++ + C CP G G D C H
Sbjct: 619 --TGQLCEVPLCAPNLCQPKQICKDQKDKANC-LCPDGSPGCAPPEDNCTCHHGHCQRSS 675
Query: 129 -VCDA---------------QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMD 171
VCD PC C P+ + Y C CP+GY G TC +M
Sbjct: 676 CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG--YNCT-CPTGY--TGPTCSEEMT 730
Query: 172 ECDLIRPCDDLVSC 185
C PC + SC
Sbjct: 731 ACH-SGPCLNGGSC 743
Score = 48.4 bits (110), Expect = 1e-04
Identities = 53/176 (30%), Positives = 72/176 (40%), Gaps = 18/176 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTS-DGQTCRTACSANP---CFGGRVPCQDLPDGRYQCGKC 76
G C D + C CP + T D C A C G CQ+ G + C C
Sbjct: 287 GGTCQDGLDTYTC-LCPETWTGWDCSEDVDECEAQGPPHCRNGGT-CQNSA-GSFHC-VC 342
Query: 77 PSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPC 136
SG+ G E C A TC G +C + C CP G G + +C +Q PC
Sbjct: 343 VSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSC-LCPPGRTGLLCHLEDMCLSQ-PC 400
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIR----PCDDLVSCRN 187
+ +C ST+P C ++G TC D+DEC + + PC+ SC N
Sbjct: 401 HGDAQC---STNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLN 453
Score = 47.2 bits (107), Expect = 2e-04
Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 11/113 (9%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGP 110
C + PC G C P G Y C CP+G+ G +C + C G SC + G
Sbjct: 694 CISAPCAHGGT-CYPQPSG-YNC-TCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGY 750
Query: 111 KCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQ 161
C +CP + G QCQ D PC C+ + + + C C G+Q
Sbjct: 751 YC-TCPPSHTGP--QCQTSTDYCVSAPCFNGGTCVNRPGT--FSCL-CAMGFQ 797
Score = 45.6 bits (103), Expect = 7e-04
Identities = 48/182 (26%), Positives = 69/182 (37%), Gaps = 16/182 (8%)
Query: 14 TPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGRVPCQDLPDG--- 69
T L +G+ GF E C + Q C+ S + P
Sbjct: 39 TCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTP 98
Query: 70 RYQCGKCPSGFHGNGVEC-YRISCRANTCFQGVSCEETQYG-PKCGSCPTGYVGDGRQCQ 127
+ C C GF G + C + C + C G P+C SC G+ G+ Q +
Sbjct: 99 SFLC-TCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQC-SCMPGWTGEQCQLR 156
Query: 128 HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDEC-DLIRPCDDLVSC 185
C A PC C+ +T P +C CP G++ G+ C D++EC PC SC
Sbjct: 157 DFCSA-NPCVNGGVCL--ATYPQIQCH-CPPGFE--GHACERDVNECFQDPGPCPKGTSC 210
Query: 186 RN 187
N
Sbjct: 211 HN 212
Score = 44.8 bits (101), Expect = 0.001
Identities = 39/142 (27%), Positives = 49/142 (34%), Gaps = 9/142 (6%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFG-GRVPCQDLPDGRYQCGKCPSGFHG 82
C GF C PG + C PC G C L + Y C +C G G
Sbjct: 982 CTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFY-C-QCLPGHTG 1039
Query: 83 NGVECYRISCRANTCFQGVSCEETQYGPK--CGSCPTGYVGDGRQCQHVCDA--QKPCGR 138
E C + CF G +CE T P CP G+ +G C H + C
Sbjct: 1040 QWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGF--EGPTCSHRAPSCGFHHCHH 1097
Query: 139 ERRCMPKSTSPYYECEGCPSGY 160
C+P + C SGY
Sbjct: 1098 GGLCLPSPKPGFPPRCACLSGY 1119
>BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 83.4 bits (197), Expect = 3e-15
Identities = 77/256 (30%), Positives = 105/256 (41%), Gaps = 28/256 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C + G+ C CP S T G C+T+ C + PCF G C + P G + C C
Sbjct: 741 GGSCNPSPGGYYCT-CPPSHT--GPQCQTSTDYCVSAPCFNGGT-CVNRP-GTFSC-LCA 794
Query: 78 SGFHGNGVEC-YRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQK 134
GF G E R SC + C +C+++ GP+C CPTGY G CQ + D AQK
Sbjct: 795 MGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC-LCPTGYTGG--SCQTLMDLCAQK 851
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECD--LIRPCDDLVSCRNEEXX 191
PC R C+ T P + C C G W G C + + C + D+ S +
Sbjct: 852 PCPRNSHCL--QTGPSFHCL-CLQG--WTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGL 906
Query: 192 XXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC---PRGRLCVNTPQYPSNP 248
G++G+ + C + C +G A C P G LC P Y
Sbjct: 907 CVDSGPSYFCHCPPGFQGSLCQDHVNPC-ESRPCQNG-ATCMAQPSGYLCQCAPGYDGQN 964
Query: 249 VSSLQGSYICVPCGGH 264
S + PC H
Sbjct: 965 CSKELDACQSQPCHNH 980
Score = 57.2 bits (132), Expect = 2e-07
Identities = 47/168 (27%), Positives = 67/168 (39%), Gaps = 15/168 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C++T F C PG S + C + PC G C DL + C CP G
Sbjct: 449 GGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGST-CLDLL-ATFHC-LCPPGL 505
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C + C C + G +C C G+ G +C+ D PC
Sbjct: 506 EGQLCEVETNECASAPCLNHADCHDLLNGFQC-ICLPGF--SGTRCEEDIDECRSSPCAN 562
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSC 185
+C + + + C+ C G++ G C ++DEC L PC SC
Sbjct: 563 GGQCQDQPGA--FHCK-CLPGFE--GPRCQTEVDEC-LSDPCPVGASC 604
Score = 56.8 bits (131), Expect = 3e-07
Identities = 79/285 (27%), Positives = 108/285 (37%), Gaps = 46/285 (16%)
Query: 32 RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS 91
+C PG T + R CSANPC G V P + QC CP GF G+ E
Sbjct: 142 QCSCMPG-WTGEQCQLRDFCSANPCVNGGVCLATYP--QIQC-HCPPGFEGHACERDVNE 197
Query: 92 C--RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRC--MPKST 147
C C +G SC T +C CP G G + + + C C MP+
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKD 256
Query: 148 SPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQG 206
S ++ C CP G+ G C V+ D C + C + +C++ +
Sbjct: 257 STFHLCL-CPPGF--IGPDCEVNPDNC-VSHQCQNGGTCQD-------GLDTYTCLCPET 305
Query: 207 WRGTGNERRREHCVDVDEC-ADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHY 265
W G + DVDEC G +C G C N+ GS+ CV C +
Sbjct: 306 WTGW------DCSEDVDECETQGPPHCRNGGTCQNS-----------AGSFHCV-CVSGW 347
Query: 266 YVNTTRPCFDPDSLVKRCDP-SYCRRFNAVCGFGQKCVCNTGWTG 309
+ D D + C P S C + V F C+C G TG
Sbjct: 348 GGTSCEENLD-DCIAATCAPGSTC--IDRVGSF--SCLCPPGRTG 387
Score = 56.0 bits (129), Expect = 5e-07
Identities = 39/112 (34%), Positives = 50/112 (44%), Gaps = 13/112 (11%)
Query: 71 YQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVC 130
Y C CP GF G+ + + C + C G +C G C C GY DG+ C
Sbjct: 914 YFC-HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLC-QCAPGY--DGQNCSKEL 969
Query: 131 DA--QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPC 179
DA +PC C PK + C CP G+ G C D+DEC L +PC
Sbjct: 970 DACQSQPCHNHGTCTPKPGG--FHC-ACPPGFV--GLRCEGDVDEC-LDQPC 1015
Score = 53.6 bits (123), Expect = 3e-06
Identities = 60/194 (30%), Positives = 74/194 (38%), Gaps = 41/194 (21%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G +C D F C+ PG + QT C ++PC G C DLP G + C CPSGF
Sbjct: 563 GGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVG-ASCLDLP-GAFFC-LCPSGF 619
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-----DGRQCQH------- 128
G C C N C C++ + C CP G G D C H
Sbjct: 620 --TGQLCEVPLCAPNLCQPKQICKDQKDKANC-LCPDGSPGCAPPEDNCTCHHGHCQRSS 676
Query: 129 -VCDA---------------QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMD 171
VCD PC C P+ + Y C CP+GY G TC +M
Sbjct: 677 CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG--YNCT-CPTGY--TGPTCSEEMT 731
Query: 172 ECDLIRPCDDLVSC 185
C PC + SC
Sbjct: 732 ACH-SGPCLNGGSC 744
Score = 50.4 bits (115), Expect = 2e-05
Identities = 46/160 (28%), Positives = 65/160 (40%), Gaps = 15/160 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA-CSANPCFGGRVPCQDLP--DGRYQCGKCP 77
G C +T F+C CP Q R C C G CQ +P D + CP
Sbjct: 208 GTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGT-CQLMPEKDSTFHLCLCP 265
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-DGRQCQHVCDAQKP- 135
GF G E +C ++ C G +C++ C CP + G D + C+ Q P
Sbjct: 266 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTC-LCPETWTGWDCSEDVDECETQGPP 324
Query: 136 -CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDEC 173
C C + S + C C SG W G +C + +D+C
Sbjct: 325 HCRNGGTCQNSAGS--FHCV-CVSG--WGGTSCEENLDDC 359
Score = 49.6 bits (113), Expect = 4e-05
Identities = 53/177 (29%), Positives = 73/177 (41%), Gaps = 20/177 (11%)
Query: 21 GERCVDTDQGFRCERCPGSQTS-----DGQTCRTACSANPCFGGRVPCQDLPDGRYQCGK 75
G C D + C CP + T D C T + GG CQ+ G + C
Sbjct: 288 GGTCQDGLDTYTC-LCPETWTGWDCSEDVDECETQGPPHCRNGGT--CQNSA-GSFHC-V 342
Query: 76 CPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
C SG+ G E C A TC G +C + C CP G G + +C +Q P
Sbjct: 343 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSC-LCPPGRTGLLCHLEDMCLSQ-P 400
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIR----PCDDLVSCRN 187
C + +C ST+P C ++G TC D+DEC + + PC+ SC N
Sbjct: 401 CHGDAQC---STNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLN 454
Score = 47.2 bits (107), Expect = 2e-04
Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 11/113 (9%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGP 110
C + PC G C P G Y C CP+G+ G +C + C G SC + G
Sbjct: 695 CISAPCAHGGT-CYPQPSG-YNC-TCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGY 751
Query: 111 KCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQ 161
C +CP + G QCQ D PC C+ + + + C C G+Q
Sbjct: 752 YC-TCPPSHTGP--QCQTSTDYCVSAPCFNGGTCVNRPGT--FSCL-CAMGFQ 798
Score = 45.6 bits (103), Expect = 7e-04
Identities = 48/182 (26%), Positives = 69/182 (37%), Gaps = 16/182 (8%)
Query: 14 TPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGRVPCQDLPDG--- 69
T L +G+ GF E C + Q C+ S + P
Sbjct: 40 TCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTP 99
Query: 70 RYQCGKCPSGFHGNGVEC-YRISCRANTCFQGVSCEETQYG-PKCGSCPTGYVGDGRQCQ 127
+ C C GF G + C + C + C G P+C SC G+ G+ Q +
Sbjct: 100 SFLC-TCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQC-SCMPGWTGEQCQLR 157
Query: 128 HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDEC-DLIRPCDDLVSC 185
C A PC C+ +T P +C CP G++ G+ C D++EC PC SC
Sbjct: 158 DFCSA-NPCVNGGVCL--ATYPQIQCH-CPPGFE--GHACERDVNECFQDPGPCPKGTSC 211
Query: 186 RN 187
N
Sbjct: 212 HN 213
Score = 44.8 bits (101), Expect = 0.001
Identities = 39/142 (27%), Positives = 49/142 (34%), Gaps = 9/142 (6%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFG-GRVPCQDLPDGRYQCGKCPSGFHG 82
C GF C PG + C PC G C L + Y C +C G G
Sbjct: 983 CTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFY-C-QCLPGHTG 1040
Query: 83 NGVECYRISCRANTCFQGVSCEETQYGPK--CGSCPTGYVGDGRQCQHVCDA--QKPCGR 138
E C + CF G +CE T P CP G+ +G C H + C
Sbjct: 1041 QWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGF--EGPTCSHRAPSCGFHHCHH 1098
Query: 139 ERRCMPKSTSPYYECEGCPSGY 160
C+P + C SGY
Sbjct: 1099 GGLCLPSPKPGFPPRCACLSGY 1120
>BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 83.4 bits (197), Expect = 3e-15
Identities = 77/256 (30%), Positives = 105/256 (41%), Gaps = 28/256 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C + G+ C CP S T G C+T+ C + PCF G C + P G + C C
Sbjct: 741 GGSCNPSPGGYYCT-CPPSHT--GPQCQTSTDYCVSAPCFNGGT-CVNRP-GTFSC-LCA 794
Query: 78 SGFHGNGVEC-YRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQK 134
GF G E R SC + C +C+++ GP+C CPTGY G CQ + D AQK
Sbjct: 795 MGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC-LCPTGYTGG--SCQTLMDLCAQK 851
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECD--LIRPCDDLVSCRNEEXX 191
PC R C+ T P + C C G W G C + + C + D+ S +
Sbjct: 852 PCPRNSHCL--QTGPSFHCL-CLQG--WTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGL 906
Query: 192 XXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC---PRGRLCVNTPQYPSNP 248
G++G+ + C + C +G A C P G LC P Y
Sbjct: 907 CVDSGPSYFCHCPPGFQGSLCQDHVNPC-ESRPCQNG-ATCMAQPSGYLCQCAPGYDGQN 964
Query: 249 VSSLQGSYICVPCGGH 264
S + PC H
Sbjct: 965 CSKELDACQSQPCHNH 980
Score = 57.2 bits (132), Expect = 2e-07
Identities = 47/168 (27%), Positives = 67/168 (39%), Gaps = 15/168 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C++T F C PG S + C + PC G C DL + C CP G
Sbjct: 449 GGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGST-CLDLL-ATFHC-LCPPGL 505
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C + C C + G +C C G+ G +C+ D PC
Sbjct: 506 EGQLCEVETNECASAPCLNHADCHDLLNGFQC-ICLPGF--SGTRCEEDIDECRSSPCAN 562
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSC 185
+C + + + C+ C G++ G C ++DEC L PC SC
Sbjct: 563 GGQCQDQPGA--FHCK-CLPGFE--GPRCQTEVDEC-LSDPCPVGASC 604
Score = 56.8 bits (131), Expect = 3e-07
Identities = 79/285 (27%), Positives = 108/285 (37%), Gaps = 46/285 (16%)
Query: 32 RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS 91
+C PG T + R CSANPC G V P + QC CP GF G+ E
Sbjct: 142 QCSCMPG-WTGEQCQLRDFCSANPCVNGGVCLATYP--QIQC-HCPPGFEGHACERDVNE 197
Query: 92 C--RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRC--MPKST 147
C C +G SC T +C CP G G + + + C C MP+
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKD 256
Query: 148 SPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQG 206
S ++ C CP G+ G C V+ D C + C + +C++ +
Sbjct: 257 STFHLCL-CPPGF--IGPDCEVNPDNC-VSHQCQNGGTCQD-------GLDTYTCLCPET 305
Query: 207 WRGTGNERRREHCVDVDEC-ADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHY 265
W G + DVDEC G +C G C N+ GS+ CV C +
Sbjct: 306 WTGW------DCSEDVDECETQGPPHCRNGGTCQNS-----------AGSFHCV-CVSGW 347
Query: 266 YVNTTRPCFDPDSLVKRCDP-SYCRRFNAVCGFGQKCVCNTGWTG 309
+ D D + C P S C + V F C+C G TG
Sbjct: 348 GGTSCEENLD-DCIAATCAPGSTC--IDRVGSF--SCLCPPGRTG 387
Score = 56.0 bits (129), Expect = 5e-07
Identities = 39/112 (34%), Positives = 50/112 (44%), Gaps = 13/112 (11%)
Query: 71 YQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVC 130
Y C CP GF G+ + + C + C G +C G C C GY DG+ C
Sbjct: 914 YFC-HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLC-QCAPGY--DGQNCSKEL 969
Query: 131 DA--QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPC 179
DA +PC C PK + C CP G+ G C D+DEC L +PC
Sbjct: 970 DACQSQPCHNHGTCTPKPGG--FHC-ACPPGFV--GLRCEGDVDEC-LDQPC 1015
Score = 53.6 bits (123), Expect = 3e-06
Identities = 60/194 (30%), Positives = 74/194 (38%), Gaps = 41/194 (21%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G +C D F C+ PG + QT C ++PC G C DLP G + C CPSGF
Sbjct: 563 GGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVG-ASCLDLP-GAFFC-LCPSGF 619
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-----DGRQCQH------- 128
G C C N C C++ + C CP G G D C H
Sbjct: 620 --TGQLCEVPLCAPNLCQPKQICKDQKDKANC-LCPDGSPGCAPPEDNCTCHHGHCQRSS 676
Query: 129 -VCDA---------------QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMD 171
VCD PC C P+ + Y C CP+GY G TC +M
Sbjct: 677 CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG--YNCT-CPTGY--TGPTCSEEMT 731
Query: 172 ECDLIRPCDDLVSC 185
C PC + SC
Sbjct: 732 ACH-SGPCLNGGSC 744
Score = 50.4 bits (115), Expect = 2e-05
Identities = 46/160 (28%), Positives = 65/160 (40%), Gaps = 15/160 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA-CSANPCFGGRVPCQDLP--DGRYQCGKCP 77
G C +T F+C CP Q R C C G CQ +P D + CP
Sbjct: 208 GTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGT-CQLMPEKDSTFHLCLCP 265
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-DGRQCQHVCDAQKP- 135
GF G E +C ++ C G +C++ C CP + G D + C+ Q P
Sbjct: 266 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTC-LCPETWTGWDCSEDVDECETQGPP 324
Query: 136 -CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDEC 173
C C + S + C C SG W G +C + +D+C
Sbjct: 325 HCRNGGTCQNSAGS--FHCV-CVSG--WGGTSCEENLDDC 359
Score = 49.6 bits (113), Expect = 4e-05
Identities = 53/177 (29%), Positives = 73/177 (41%), Gaps = 20/177 (11%)
Query: 21 GERCVDTDQGFRCERCPGSQTS-----DGQTCRTACSANPCFGGRVPCQDLPDGRYQCGK 75
G C D + C CP + T D C T + GG CQ+ G + C
Sbjct: 288 GGTCQDGLDTYTC-LCPETWTGWDCSEDVDECETQGPPHCRNGGT--CQNSA-GSFHC-V 342
Query: 76 CPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
C SG+ G E C A TC G +C + C CP G G + +C +Q P
Sbjct: 343 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSC-LCPPGRTGLLCHLEDMCLSQ-P 400
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIR----PCDDLVSCRN 187
C + +C ST+P C ++G TC D+DEC + + PC+ SC N
Sbjct: 401 CHGDAQC---STNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLN 454
Score = 47.2 bits (107), Expect = 2e-04
Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 11/113 (9%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGP 110
C + PC G C P G Y C CP+G+ G +C + C G SC + G
Sbjct: 695 CISAPCAHGGT-CYPQPSG-YNC-TCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGY 751
Query: 111 KCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQ 161
C +CP + G QCQ D PC C+ + + + C C G+Q
Sbjct: 752 YC-TCPPSHTGP--QCQTSTDYCVSAPCFNGGTCVNRPGT--FSCL-CAMGFQ 798
Score = 45.6 bits (103), Expect = 7e-04
Identities = 48/182 (26%), Positives = 69/182 (37%), Gaps = 16/182 (8%)
Query: 14 TPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGRVPCQDLPDG--- 69
T L +G+ GF E C + Q C+ S + P
Sbjct: 40 TCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTP 99
Query: 70 RYQCGKCPSGFHGNGVEC-YRISCRANTCFQGVSCEETQYG-PKCGSCPTGYVGDGRQCQ 127
+ C C GF G + C + C + C G P+C SC G+ G+ Q +
Sbjct: 100 SFLC-TCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQC-SCMPGWTGEQCQLR 157
Query: 128 HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDEC-DLIRPCDDLVSC 185
C A PC C+ +T P +C CP G++ G+ C D++EC PC SC
Sbjct: 158 DFCSA-NPCVNGGVCL--ATYPQIQCH-CPPGFE--GHACERDVNECFQDPGPCPKGTSC 211
Query: 186 RN 187
N
Sbjct: 212 HN 213
Score = 44.8 bits (101), Expect = 0.001
Identities = 39/142 (27%), Positives = 49/142 (34%), Gaps = 9/142 (6%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFG-GRVPCQDLPDGRYQCGKCPSGFHG 82
C GF C PG + C PC G C L + Y C +C G G
Sbjct: 983 CTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFY-C-QCLPGHTG 1040
Query: 83 NGVECYRISCRANTCFQGVSCEETQYGPK--CGSCPTGYVGDGRQCQHVCDA--QKPCGR 138
E C + CF G +CE T P CP G+ +G C H + C
Sbjct: 1041 QWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGF--EGPTCSHRAPSCGFHHCHH 1098
Query: 139 ERRCMPKSTSPYYECEGCPSGY 160
C+P + C SGY
Sbjct: 1099 GGLCLPSPKPGFPPRCACLSGY 1120
>AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 83.4 bits (197), Expect = 3e-15
Identities = 77/256 (30%), Positives = 105/256 (41%), Gaps = 28/256 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C + G+ C CP S T G C+T+ C + PCF G C + P G + C C
Sbjct: 741 GGSCNPSPGGYYCT-CPPSHT--GPQCQTSTDYCVSAPCFNGGT-CVNRP-GTFSC-LCA 794
Query: 78 SGFHGNGVEC-YRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQK 134
GF G E R SC + C +C+++ GP+C CPTGY G CQ + D AQK
Sbjct: 795 MGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC-LCPTGYTGG--SCQTLMDLCAQK 851
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECD--LIRPCDDLVSCRNEEXX 191
PC R C+ T P + C C G W G C + + C + D+ S +
Sbjct: 852 PCPRNSHCL--QTGPSFHCL-CLQG--WTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGL 906
Query: 192 XXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC---PRGRLCVNTPQYPSNP 248
G++G+ + C + C +G A C P G LC P Y
Sbjct: 907 CVDSGPSYFCHCPPGFQGSLCQDHVNPC-ESRPCQNG-ATCMAQPSGYLCQCAPGYDGQN 964
Query: 249 VSSLQGSYICVPCGGH 264
S + PC H
Sbjct: 965 CSKELDACQSQPCHNH 980
Score = 57.2 bits (132), Expect = 2e-07
Identities = 47/168 (27%), Positives = 67/168 (39%), Gaps = 15/168 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C++T F C PG S + C + PC G C DL + C CP G
Sbjct: 449 GGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGST-CLDLL-ATFHC-LCPPGL 505
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C + C C + G +C C G+ G +C+ D PC
Sbjct: 506 EGQLCEVETNECASAPCLNHADCHDLLNGFQC-ICLPGF--SGTRCEEDIDECRSSPCAN 562
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSC 185
+C + + + C+ C G++ G C ++DEC L PC SC
Sbjct: 563 GGQCQDQPGA--FHCK-CLPGFE--GPRCQTEVDEC-LSDPCPVGASC 604
Score = 56.8 bits (131), Expect = 3e-07
Identities = 79/285 (27%), Positives = 108/285 (37%), Gaps = 46/285 (16%)
Query: 32 RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS 91
+C PG T + R CSANPC G V P + QC CP GF G+ E
Sbjct: 142 QCSCMPG-WTGEQCQLRDFCSANPCVNGGVCLATYP--QIQC-HCPPGFEGHACERDVNE 197
Query: 92 C--RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRC--MPKST 147
C C +G SC T +C CP G G + + + C C MP+
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKD 256
Query: 148 SPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQG 206
S ++ C CP G+ G C V+ D C + C + +C++ +
Sbjct: 257 STFHLCL-CPPGF--IGPDCEVNPDNC-VSHQCQNGGTCQD-------GLDTYTCLCPET 305
Query: 207 WRGTGNERRREHCVDVDEC-ADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHY 265
W G + DVDEC G +C G C N+ GS+ CV C +
Sbjct: 306 WTGW------DCSEDVDECETQGPPHCRNGGTCQNS-----------AGSFHCV-CVSGW 347
Query: 266 YVNTTRPCFDPDSLVKRCDP-SYCRRFNAVCGFGQKCVCNTGWTG 309
+ D D + C P S C + V F C+C G TG
Sbjct: 348 GGTSCEENLD-DCIAATCAPGSTC--IDRVGSF--SCLCPPGRTG 387
Score = 56.0 bits (129), Expect = 5e-07
Identities = 39/112 (34%), Positives = 50/112 (44%), Gaps = 13/112 (11%)
Query: 71 YQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVC 130
Y C CP GF G+ + + C + C G +C G C C GY DG+ C
Sbjct: 914 YFC-HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLC-QCAPGY--DGQNCSKEL 969
Query: 131 DA--QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPC 179
DA +PC C PK + C CP G+ G C D+DEC L +PC
Sbjct: 970 DACQSQPCHNHGTCTPKPGG--FHC-ACPPGFV--GLRCEGDVDEC-LDQPC 1015
Score = 53.6 bits (123), Expect = 3e-06
Identities = 60/194 (30%), Positives = 74/194 (38%), Gaps = 41/194 (21%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G +C D F C+ PG + QT C ++PC G C DLP G + C CPSGF
Sbjct: 563 GGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVG-ASCLDLP-GAFFC-LCPSGF 619
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-----DGRQCQH------- 128
G C C N C C++ + C CP G G D C H
Sbjct: 620 --TGQLCEVPLCAPNLCQPKQICKDQKDKANC-LCPDGSPGCAPPEDNCTCHHGHCQRSS 676
Query: 129 -VCDA---------------QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMD 171
VCD PC C P+ + Y C CP+GY G TC +M
Sbjct: 677 CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG--YNCT-CPTGY--TGPTCSEEMT 731
Query: 172 ECDLIRPCDDLVSC 185
C PC + SC
Sbjct: 732 ACH-SGPCLNGGSC 744
Score = 50.4 bits (115), Expect = 2e-05
Identities = 46/160 (28%), Positives = 65/160 (40%), Gaps = 15/160 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA-CSANPCFGGRVPCQDLP--DGRYQCGKCP 77
G C +T F+C CP Q R C C G CQ +P D + CP
Sbjct: 208 GTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGT-CQLMPEKDSTFHLCLCP 265
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-DGRQCQHVCDAQKP- 135
GF G E +C ++ C G +C++ C CP + G D + C+ Q P
Sbjct: 266 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTC-LCPETWTGWDCSEDVDECETQGPP 324
Query: 136 -CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDEC 173
C C + S + C C SG W G +C + +D+C
Sbjct: 325 HCRNGGTCQNSAGS--FHCV-CVSG--WGGTSCEENLDDC 359
Score = 49.6 bits (113), Expect = 4e-05
Identities = 53/177 (29%), Positives = 73/177 (41%), Gaps = 20/177 (11%)
Query: 21 GERCVDTDQGFRCERCPGSQTS-----DGQTCRTACSANPCFGGRVPCQDLPDGRYQCGK 75
G C D + C CP + T D C T + GG CQ+ G + C
Sbjct: 288 GGTCQDGLDTYTC-LCPETWTGWDCSEDVDECETQGPPHCRNGGT--CQNSA-GSFHC-V 342
Query: 76 CPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
C SG+ G E C A TC G +C + C CP G G + +C +Q P
Sbjct: 343 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSC-LCPPGRTGLLCHLEDMCLSQ-P 400
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIR----PCDDLVSCRN 187
C + +C ST+P C ++G TC D+DEC + + PC+ SC N
Sbjct: 401 CHGDAQC---STNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLN 454
Score = 47.2 bits (107), Expect = 2e-04
Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 11/113 (9%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGP 110
C + PC G C P G Y C CP+G+ G +C + C G SC + G
Sbjct: 695 CISAPCAHGGT-CYPQPSG-YNC-TCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGY 751
Query: 111 KCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQ 161
C +CP + G QCQ D PC C+ + + + C C G+Q
Sbjct: 752 YC-TCPPSHTGP--QCQTSTDYCVSAPCFNGGTCVNRPGT--FSCL-CAMGFQ 798
Score = 45.6 bits (103), Expect = 7e-04
Identities = 48/182 (26%), Positives = 69/182 (37%), Gaps = 16/182 (8%)
Query: 14 TPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGRVPCQDLPDG--- 69
T L +G+ GF E C + Q C+ S + P
Sbjct: 40 TCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTP 99
Query: 70 RYQCGKCPSGFHGNGVEC-YRISCRANTCFQGVSCEETQYG-PKCGSCPTGYVGDGRQCQ 127
+ C C GF G + C + C + C G P+C SC G+ G+ Q +
Sbjct: 100 SFLC-TCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQC-SCMPGWTGEQCQLR 157
Query: 128 HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDEC-DLIRPCDDLVSC 185
C A PC C+ +T P +C CP G++ G+ C D++EC PC SC
Sbjct: 158 DFCSA-NPCVNGGVCL--ATYPQIQCH-CPPGFE--GHACERDVNECFQDPGPCPKGTSC 211
Query: 186 RN 187
N
Sbjct: 212 HN 213
Score = 44.8 bits (101), Expect = 0.001
Identities = 39/142 (27%), Positives = 49/142 (34%), Gaps = 9/142 (6%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFG-GRVPCQDLPDGRYQCGKCPSGFHG 82
C GF C PG + C PC G C L + Y C +C G G
Sbjct: 983 CTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFY-C-QCLPGHTG 1040
Query: 83 NGVECYRISCRANTCFQGVSCEETQYGPK--CGSCPTGYVGDGRQCQHVCDA--QKPCGR 138
E C + CF G +CE T P CP G+ +G C H + C
Sbjct: 1041 QWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGF--EGPTCSHRAPSCGFHHCHH 1098
Query: 139 ERRCMPKSTSPYYECEGCPSGY 160
C+P + C SGY
Sbjct: 1099 GGLCLPSPKPGFPPRCACLSGY 1120
>AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2005
Score = 83.4 bits (197), Expect = 3e-15
Identities = 77/256 (30%), Positives = 105/256 (41%), Gaps = 28/256 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C + G+ C CP S T G C+T+ C + PCF G C + P G + C C
Sbjct: 743 GGSCNPSPGGYYCT-CPPSHT--GPQCQTSTDYCVSAPCFNGGT-CVNRP-GTFSC-LCA 796
Query: 78 SGFHGNGVEC-YRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQK 134
GF G E R SC + C +C+++ GP+C CPTGY G CQ + D AQK
Sbjct: 797 MGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC-LCPTGYTGG--SCQTLMDLCAQK 853
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECD--LIRPCDDLVSCRNEEXX 191
PC R C+ T P + C C G W G C + + C + D+ S +
Sbjct: 854 PCPRNSHCL--QTGPSFHCL-CLQG--WTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGL 908
Query: 192 XXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC---PRGRLCVNTPQYPSNP 248
G++G+ + C + C +G A C P G LC P Y
Sbjct: 909 CVDSGPSYFCHCPPGFQGSLCQDHVNPC-ESRPCQNG-ATCMAQPSGYLCQCAPGYDGQN 966
Query: 249 VSSLQGSYICVPCGGH 264
S + PC H
Sbjct: 967 CSKELDACQSQPCHNH 982
Score = 58.4 bits (135), Expect = 9e-08
Identities = 80/285 (28%), Positives = 109/285 (38%), Gaps = 46/285 (16%)
Query: 32 RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS 91
+C PG T + R CSANPC G V P + QC CP GF G+ E
Sbjct: 144 QCSCMPG-WTGEQCQLRDFCSANPCVNGGVCLATYP--QIQC-HCPPGFEGHACERDVNE 199
Query: 92 C--RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRC--MPKST 147
C C +G SC T +C CP G G + + + C C MP+
Sbjct: 200 CFQDPGPCPKGTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKD 258
Query: 148 SPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQG 206
S ++ C CP G+ G C V+ D C + C + +C++ +
Sbjct: 259 STFHLCL-CPPGF--IGPDCEVNPDNC-VSHQCQNGGTCQD-------GLDTYTCLCPET 307
Query: 207 WRGTGNERRREHCVDVDEC-ADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHY 265
W G + DVDEC A G +C G C N+ GS+ CV C +
Sbjct: 308 WTGW------DCSEDVDECEAQGPPHCRNGGTCQNS-----------AGSFHCV-CVSGW 349
Query: 266 YVNTTRPCFDPDSLVKRCDP-SYCRRFNAVCGFGQKCVCNTGWTG 309
+ D D + C P S C + V F C+C G TG
Sbjct: 350 GGTSCEENLD-DCIAATCAPGSTC--IDRVGSF--SCLCPPGRTG 389
Score = 57.2 bits (132), Expect = 2e-07
Identities = 47/168 (27%), Positives = 67/168 (39%), Gaps = 15/168 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C++T F C PG S + C + PC G C DL + C CP G
Sbjct: 451 GGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGST-CLDLL-ATFHC-LCPPGL 507
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C + C C + G +C C G+ G +C+ D PC
Sbjct: 508 EGQLCEVETNECASAPCLNHADCHDLLNGFQC-ICLPGF--SGTRCEEDIDECRSSPCAN 564
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSC 185
+C + + + C+ C G++ G C ++DEC L PC SC
Sbjct: 565 GGQCQDQPGA--FHCK-CLPGFE--GPRCQTEVDEC-LSDPCPVGASC 606
Score = 56.0 bits (129), Expect = 5e-07
Identities = 39/112 (34%), Positives = 50/112 (44%), Gaps = 13/112 (11%)
Query: 71 YQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVC 130
Y C CP GF G+ + + C + C G +C G C C GY DG+ C
Sbjct: 916 YFC-HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLC-QCAPGY--DGQNCSKEL 971
Query: 131 DA--QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPC 179
DA +PC C PK + C CP G+ G C D+DEC L +PC
Sbjct: 972 DACQSQPCHNHGTCTPKPGG--FHC-ACPPGFV--GLRCEGDVDEC-LDQPC 1017
Score = 53.6 bits (123), Expect = 3e-06
Identities = 60/194 (30%), Positives = 74/194 (38%), Gaps = 41/194 (21%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G +C D F C+ PG + QT C ++PC G C DLP G + C CPSGF
Sbjct: 565 GGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVG-ASCLDLP-GAFFC-LCPSGF 621
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-----DGRQCQH------- 128
G C C N C C++ + C CP G G D C H
Sbjct: 622 --TGQLCEVPLCAPNLCQPKQICKDQKDKANC-LCPDGSPGCAPPEDNCTCHHGHCQRSS 678
Query: 129 -VCDA---------------QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMD 171
VCD PC C P+ + Y C CP+GY G TC +M
Sbjct: 679 CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG--YNCT-CPTGY--TGPTCSEEMT 733
Query: 172 ECDLIRPCDDLVSC 185
C PC + SC
Sbjct: 734 ACH-SGPCLNGGSC 746
Score = 52.0 bits (119), Expect = 8e-06
Identities = 47/160 (29%), Positives = 66/160 (41%), Gaps = 15/160 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA-CSANPCFGGRVPCQDLP--DGRYQCGKCP 77
G C +T F+C CP Q R C C G CQ +P D + CP
Sbjct: 210 GTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGT-CQLMPEKDSTFHLCLCP 267
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-DGRQCQHVCDAQKP- 135
GF G E +C ++ C G +C++ C CP + G D + C+AQ P
Sbjct: 268 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTC-LCPETWTGWDCSEDVDECEAQGPP 326
Query: 136 -CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDEC 173
C C + S + C C SG W G +C + +D+C
Sbjct: 327 HCRNGGTCQNSAGS--FHCV-CVSG--WGGTSCEENLDDC 361
Score = 48.4 bits (110), Expect = 1e-04
Identities = 53/176 (30%), Positives = 72/176 (40%), Gaps = 18/176 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTS-DGQTCRTACSANP---CFGGRVPCQDLPDGRYQCGKC 76
G C D + C CP + T D C A C G CQ+ G + C C
Sbjct: 290 GGTCQDGLDTYTC-LCPETWTGWDCSEDVDECEAQGPPHCRNGGT-CQNSA-GSFHC-VC 345
Query: 77 PSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPC 136
SG+ G E C A TC G +C + C CP G G + +C +Q PC
Sbjct: 346 VSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSC-LCPPGRTGLLCHLEDMCLSQ-PC 403
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIR----PCDDLVSCRN 187
+ +C ST+P C ++G TC D+DEC + + PC+ SC N
Sbjct: 404 HGDAQC---STNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLN 456
Score = 47.2 bits (107), Expect = 2e-04
Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 11/113 (9%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGP 110
C + PC G C P G Y C CP+G+ G +C + C G SC + G
Sbjct: 697 CISAPCAHGGT-CYPQPSG-YNC-TCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGY 753
Query: 111 KCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQ 161
C +CP + G QCQ D PC C+ + + + C C G+Q
Sbjct: 754 YC-TCPPSHTGP--QCQTSTDYCVSAPCFNGGTCVNRPGT--FSCL-CAMGFQ 800
Score = 45.6 bits (103), Expect = 7e-04
Identities = 48/182 (26%), Positives = 69/182 (37%), Gaps = 16/182 (8%)
Query: 14 TPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGRVPCQDLPDG--- 69
T L +G+ GF E C + Q C+ S + P
Sbjct: 42 TCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTP 101
Query: 70 RYQCGKCPSGFHGNGVECY-RISCRANTCFQGVSCEETQYG-PKCGSCPTGYVGDGRQCQ 127
+ C C GF G + C + C + C G P+C SC G+ G+ Q +
Sbjct: 102 SFLC-TCLPGFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQC-SCMPGWTGEQCQLR 159
Query: 128 HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDEC-DLIRPCDDLVSC 185
C A PC C+ +T P +C CP G++ G+ C D++EC PC SC
Sbjct: 160 DFCSA-NPCVNGGVCL--ATYPQIQCH-CPPGFE--GHACERDVNECFQDPGPCPKGTSC 213
Query: 186 RN 187
N
Sbjct: 214 HN 215
Score = 44.8 bits (101), Expect = 0.001
Identities = 39/142 (27%), Positives = 49/142 (34%), Gaps = 9/142 (6%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFG-GRVPCQDLPDGRYQCGKCPSGFHG 82
C GF C PG + C PC G C L + Y C +C G G
Sbjct: 985 CTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFY-C-QCLPGHTG 1042
Query: 83 NGVECYRISCRANTCFQGVSCEETQYGPK--CGSCPTGYVGDGRQCQHVCDA--QKPCGR 138
E C + CF G +CE T P CP G+ +G C H + C
Sbjct: 1043 QWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGF--EGPTCSHRAPSCGFHHCHH 1100
Query: 139 ERRCMPKSTSPYYECEGCPSGY 160
C+P + C SGY
Sbjct: 1101 GGLCLPSPKPGFPPRCACLSGY 1122
>M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein.
Length = 1394
Score = 81.0 bits (191), Expect = 2e-14
Identities = 89/314 (28%), Positives = 125/314 (39%), Gaps = 54/314 (17%)
Query: 18 LCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSA-NPCFGGRVPCQDLPDGRYQCGK 75
+C CV+T FRCE C G + + C NP C + P G YQC
Sbjct: 639 VCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSP-GSYQCVP 697
Query: 76 CPSGFHGNGVECYRIS-C-RANTCFQGVSCEETQYGPKCGSCPTGYVG--DGRQCQHVCD 131
C GF G +C + C N C G C + C SC GY D + C+ + +
Sbjct: 698 CTEGFRGWNGQCLDVDECLEPNVCANG-DCSNLEGSYMC-SCHKGYTRTPDHKHCRDIDE 755
Query: 132 AQKP--CGRERRCMPKSTSPYYECEGCPSGYQWNGYT--CVDMDECDLIRPCDDLVSCRN 187
Q+ C + C K+T + C C GYQ + C D+DEC C CRN
Sbjct: 756 CQQGNLCVNGQ-C--KNTEGSFRCT-CGQGYQLSAAKDQCEDIDECQHRHLCAH-GQCRN 810
Query: 188 EEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSN 247
E QG+R +G +HC D++EC + ++ C RG C+NT
Sbjct: 811 TEGSFQCVC-------DQGYRASG---LGDHCEDINECLEDKSVCQRGD-CINT------ 853
Query: 248 PVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCD-PSYC----RRFNAVCGFGQKCV 302
GSY C C + ++ + C D + C+ P C N F CV
Sbjct: 854 -----AGSYDCT-CPDGFQLDDNKTCQD----INECEHPGLCGPQGECLNTEGSF--HCV 901
Query: 303 CNTGW--TGNGTVC 314
C G+ + +G C
Sbjct: 902 CQQGFSISADGRTC 915
Score = 61.3 bits (142), Expect = 1e-08
Identities = 55/184 (29%), Positives = 85/184 (46%), Gaps = 23/184 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQT-CRTA--CS-ANPCFGGRVPCQDLPDGRYQC 73
LCV +C +T+ FRC G Q S + C C + C G+ C++ +G +QC
Sbjct: 761 LCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQ--CRNT-EGSFQC 817
Query: 74 GKCPSGFHGNGV--ECYRIS-CRAN--TCFQGVSCEETQYGPKCGSCPTGY-VGDGRQCQ 127
C G+ +G+ C I+ C + C +G C T C +CP G+ + D + CQ
Sbjct: 818 -VCDQGYRASGLGDHCEDINECLEDKSVCQRG-DCINTAGSYDC-TCPDGFQLDDNKTCQ 874
Query: 128 HVCDAQKP--CGRERRCMPKSTSPYYECEGCPSGYQWN--GYTCVDMDECDLIRPCDDLV 183
+ + + P CG + C+ +T + C C G+ + G TC D+DEC CD
Sbjct: 875 DINECEHPGLCGPQGECL--NTEGSFHCV-CQQGFSISADGRTCEDIDECVNNTVCDSHG 931
Query: 184 SCRN 187
C N
Sbjct: 932 FCDN 935
Score = 50.8 bits (116), Expect = 2e-05
Identities = 53/186 (28%), Positives = 75/186 (40%), Gaps = 22/186 (11%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSD-GQTCRTACSANPCFGGRVPCQ--DLPD--GRYQ 72
LC +C +T+ F+C G + S G C N C + CQ D + G Y
Sbjct: 802 LCAHGQCRNTEGSFQCVCDQGYRASGLGDHCE---DINECLEDKSVCQRGDCINTAGSYD 858
Query: 73 CGKCPSGFH-GNGVECYRIS-CR-ANTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQCQ 127
C CP GF + C I+ C C C T+ C C G+ DGR C+
Sbjct: 859 C-TCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHC-VCQQGFSISADGRTCE 916
Query: 128 HV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLV 183
+ C C C +T+ + C C G+Q +G CVD++EC+L+
Sbjct: 917 DIDECVNNTVCDSHGFC--DNTAGSFRCL-CYQGFQAPQDGQGCVDVNECELLSGVCGEA 973
Query: 184 SCRNEE 189
C N E
Sbjct: 974 FCENVE 979
Score = 39.5 bits (88), Expect = 0.046
Identities = 48/176 (27%), Positives = 66/176 (37%), Gaps = 32/176 (18%)
Query: 151 YECEGCPSGYQWNGYT--CVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWR 208
Y C C GY+++ CVD+DEC ++ C N E +G
Sbjct: 569 YTCI-CYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEG-- 625
Query: 209 GTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVN 268
+C+DVDEC C G CVNT G++ C C Y +
Sbjct: 626 --------TNCIDVDECLRPDV-CGEGH-CVNT-----------VGAFRCEYCDSGYRMT 664
Query: 269 TTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCV-CNTGWTG-NGTVCGLDRDLD 321
C D D + +PS C V G +CV C G+ G NG +D L+
Sbjct: 665 QRGRCEDIDECL---NPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE 717
Score = 39.1 bits (87), Expect = 0.061
Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 26/130 (20%)
Query: 205 QGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGH 264
+G+R + +R+ CVD+DEC + C +GR C NT +GS++C+ G
Sbjct: 575 EGYRFSEQQRK---CVDIDECTQVQHLCSQGR-CENT-----------EGSFLCICPAGF 619
Query: 265 YYVNTTRPCFDPDSLVKR--CDPSYCRRFNAVCGFGQKC-VCNTGW--TGNGTVCGLDRD 319
C D D ++ C +C N V F +C C++G+ T G +D
Sbjct: 620 MASEEGTNCIDVDECLRPDVCGEGHC--VNTVGAF--RCEYCDSGYRMTQRGRCEDIDEC 675
Query: 320 LDGH--PDEQ 327
L+ PDEQ
Sbjct: 676 LNPSTCPDEQ 685
Score = 37.1 bits (82), Expect = 0.25
Identities = 34/138 (24%), Positives = 51/138 (36%), Gaps = 10/138 (7%)
Query: 25 VDTDQGF-RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
V T GF +C++CP + G C CQD+ + + Q G CP+G N
Sbjct: 259 VGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQ-GVCPNGECLN 317
Query: 84 GVECYRISCR----ANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRE 139
+ YR +C+ + F + + G C V GRQC + +
Sbjct: 318 TMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPC-YRLVSSGRQCMYPLSVHL---TK 373
Query: 140 RRCMPKSTSPYYECEGCP 157
+ C CE CP
Sbjct: 374 QLCCCSVGKAGPHCEKCP 391
>BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming growth
factor beta binding protein 1 protein.
Length = 1395
Score = 81.0 bits (191), Expect = 2e-14
Identities = 89/314 (28%), Positives = 125/314 (39%), Gaps = 54/314 (17%)
Query: 18 LCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSA-NPCFGGRVPCQDLPDGRYQCGK 75
+C CV+T FRCE C G + + C NP C + P G YQC
Sbjct: 640 VCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSP-GSYQCVP 698
Query: 76 CPSGFHGNGVECYRIS-C-RANTCFQGVSCEETQYGPKCGSCPTGYVG--DGRQCQHVCD 131
C GF G +C + C N C G C + C SC GY D + C+ + +
Sbjct: 699 CTEGFRGWNGQCLDVDECLEPNVCANG-DCSNLEGSYMC-SCHKGYTRTPDHKHCRDIDE 756
Query: 132 AQKP--CGRERRCMPKSTSPYYECEGCPSGYQWNGYT--CVDMDECDLIRPCDDLVSCRN 187
Q+ C + C K+T + C C GYQ + C D+DEC C CRN
Sbjct: 757 CQQGNLCVNGQ-C--KNTEGSFRCT-CGQGYQLSAAKDQCEDIDECQHRHLCAH-GQCRN 811
Query: 188 EEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSN 247
E QG+R +G +HC D++EC + ++ C RG C+NT
Sbjct: 812 TEGSFQCVC-------DQGYRASG---LGDHCEDINECLEDKSVCQRGD-CINT------ 854
Query: 248 PVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCD-PSYC----RRFNAVCGFGQKCV 302
GSY C C + ++ + C D + C+ P C N F CV
Sbjct: 855 -----AGSYDCT-CPDGFQLDDNKTCQD----INECEHPGLCGPQGECLNTEGSF--HCV 902
Query: 303 CNTGW--TGNGTVC 314
C G+ + +G C
Sbjct: 903 CQQGFSISADGRTC 916
Score = 61.3 bits (142), Expect = 1e-08
Identities = 55/184 (29%), Positives = 85/184 (46%), Gaps = 23/184 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQT-CRTA--CS-ANPCFGGRVPCQDLPDGRYQC 73
LCV +C +T+ FRC G Q S + C C + C G+ C++ +G +QC
Sbjct: 762 LCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQ--CRNT-EGSFQC 818
Query: 74 GKCPSGFHGNGV--ECYRIS-CRAN--TCFQGVSCEETQYGPKCGSCPTGY-VGDGRQCQ 127
C G+ +G+ C I+ C + C +G C T C +CP G+ + D + CQ
Sbjct: 819 -VCDQGYRASGLGDHCEDINECLEDKSVCQRG-DCINTAGSYDC-TCPDGFQLDDNKTCQ 875
Query: 128 HVCDAQKP--CGRERRCMPKSTSPYYECEGCPSGYQWN--GYTCVDMDECDLIRPCDDLV 183
+ + + P CG + C+ +T + C C G+ + G TC D+DEC CD
Sbjct: 876 DINECEHPGLCGPQGECL--NTEGSFHCV-CQQGFSISADGRTCEDIDECVNNTVCDSHG 932
Query: 184 SCRN 187
C N
Sbjct: 933 FCDN 936
Score = 50.8 bits (116), Expect = 2e-05
Identities = 53/186 (28%), Positives = 75/186 (40%), Gaps = 22/186 (11%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSD-GQTCRTACSANPCFGGRVPCQ--DLPD--GRYQ 72
LC +C +T+ F+C G + S G C N C + CQ D + G Y
Sbjct: 803 LCAHGQCRNTEGSFQCVCDQGYRASGLGDHCE---DINECLEDKSVCQRGDCINTAGSYD 859
Query: 73 CGKCPSGFH-GNGVECYRIS-CR-ANTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQCQ 127
C CP GF + C I+ C C C T+ C C G+ DGR C+
Sbjct: 860 C-TCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHC-VCQQGFSISADGRTCE 917
Query: 128 HV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLV 183
+ C C C +T+ + C C G+Q +G CVD++EC+L+
Sbjct: 918 DIDECVNNTVCDSHGFC--DNTAGSFRCL-CYQGFQAPQDGQGCVDVNECELLSGVCGEA 974
Query: 184 SCRNEE 189
C N E
Sbjct: 975 FCENVE 980
Score = 40.3 bits (90), Expect = 0.026
Identities = 35/138 (25%), Positives = 52/138 (37%), Gaps = 9/138 (6%)
Query: 25 VDTDQGF-RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
V T GF +C++CP + G C CQD+ + + Q G CP+G N
Sbjct: 259 VGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQ-GVCPNGECLN 317
Query: 84 GVECYRISCR----ANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRE 139
+ YR +C+ + F + + G C V GRQC H ++
Sbjct: 318 TMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPC-YRLVSSGRQCMHPLSVH--LTKQ 374
Query: 140 RRCMPKSTSPYYECEGCP 157
C + CE CP
Sbjct: 375 LCCCSVGKAWGPHCEKCP 392
Score = 39.5 bits (88), Expect = 0.046
Identities = 48/176 (27%), Positives = 66/176 (37%), Gaps = 32/176 (18%)
Query: 151 YECEGCPSGYQWNGYT--CVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWR 208
Y C C GY+++ CVD+DEC ++ C N E +G
Sbjct: 570 YTCI-CYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEG-- 626
Query: 209 GTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVN 268
+C+DVDEC C G CVNT G++ C C Y +
Sbjct: 627 --------TNCIDVDECLRPDV-CGEGH-CVNT-----------VGAFRCEYCDSGYRMT 665
Query: 269 TTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCV-CNTGWTG-NGTVCGLDRDLD 321
C D D + +PS C V G +CV C G+ G NG +D L+
Sbjct: 666 QRGRCEDIDECL---NPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE 718
Score = 39.1 bits (87), Expect = 0.061
Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 26/130 (20%)
Query: 205 QGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGH 264
+G+R + +R+ CVD+DEC + C +GR C NT +GS++C+ G
Sbjct: 576 EGYRFSEQQRK---CVDIDECTQVQHLCSQGR-CENT-----------EGSFLCICPAGF 620
Query: 265 YYVNTTRPCFDPDSLVKR--CDPSYCRRFNAVCGFGQKC-VCNTGW--TGNGTVCGLDRD 319
C D D ++ C +C N V F +C C++G+ T G +D
Sbjct: 621 MASEEGTNCIDVDECLRPDVCGEGHC--VNTVGAF--RCEYCDSGYRMTQRGRCEDIDEC 676
Query: 320 LDGH--PDEQ 327
L+ PDEQ
Sbjct: 677 LNPSTCPDEQ 686
>AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth
factor-beta binding protein-1S protein.
Length = 1394
Score = 81.0 bits (191), Expect = 2e-14
Identities = 89/314 (28%), Positives = 125/314 (39%), Gaps = 54/314 (17%)
Query: 18 LCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSA-NPCFGGRVPCQDLPDGRYQCGK 75
+C CV+T FRCE C G + + C NP C + P G YQC
Sbjct: 639 VCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSP-GSYQCVP 697
Query: 76 CPSGFHGNGVECYRIS-C-RANTCFQGVSCEETQYGPKCGSCPTGYVG--DGRQCQHVCD 131
C GF G +C + C N C G C + C SC GY D + C+ + +
Sbjct: 698 CTEGFRGWNGQCLDVDECLEPNVCANG-DCSNLEGSYMC-SCHKGYTRTPDHKHCRDIDE 755
Query: 132 AQKP--CGRERRCMPKSTSPYYECEGCPSGYQWNGYT--CVDMDECDLIRPCDDLVSCRN 187
Q+ C + C K+T + C C GYQ + C D+DEC C CRN
Sbjct: 756 CQQGNLCVNGQ-C--KNTEGSFRCT-CGQGYQLSAAKDQCEDIDECQHRHLCAH-GQCRN 810
Query: 188 EEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSN 247
E QG+R +G +HC D++EC + ++ C RG C+NT
Sbjct: 811 TEGSFQCVC-------DQGYRASG---LGDHCEDINECLEDKSVCQRGD-CINT------ 853
Query: 248 PVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCD-PSYC----RRFNAVCGFGQKCV 302
GSY C C + ++ + C D + C+ P C N F CV
Sbjct: 854 -----AGSYDCT-CPDGFQLDDNKTCQD----INECEHPGLCGPQGECLNTEGSF--HCV 901
Query: 303 CNTGW--TGNGTVC 314
C G+ + +G C
Sbjct: 902 CQQGFSISADGRTC 915
Score = 61.3 bits (142), Expect = 1e-08
Identities = 55/184 (29%), Positives = 85/184 (46%), Gaps = 23/184 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQT-CRTA--CS-ANPCFGGRVPCQDLPDGRYQC 73
LCV +C +T+ FRC G Q S + C C + C G+ C++ +G +QC
Sbjct: 761 LCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQ--CRNT-EGSFQC 817
Query: 74 GKCPSGFHGNGV--ECYRIS-CRAN--TCFQGVSCEETQYGPKCGSCPTGY-VGDGRQCQ 127
C G+ +G+ C I+ C + C +G C T C +CP G+ + D + CQ
Sbjct: 818 -VCDQGYRASGLGDHCEDINECLEDKSVCQRG-DCINTAGSYDC-TCPDGFQLDDNKTCQ 874
Query: 128 HVCDAQKP--CGRERRCMPKSTSPYYECEGCPSGYQWN--GYTCVDMDECDLIRPCDDLV 183
+ + + P CG + C+ +T + C C G+ + G TC D+DEC CD
Sbjct: 875 DINECEHPGLCGPQGECL--NTEGSFHCV-CQQGFSISADGRTCEDIDECVNNTVCDSHG 931
Query: 184 SCRN 187
C N
Sbjct: 932 FCDN 935
Score = 50.8 bits (116), Expect = 2e-05
Identities = 53/186 (28%), Positives = 75/186 (40%), Gaps = 22/186 (11%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSD-GQTCRTACSANPCFGGRVPCQ--DLPD--GRYQ 72
LC +C +T+ F+C G + S G C N C + CQ D + G Y
Sbjct: 802 LCAHGQCRNTEGSFQCVCDQGYRASGLGDHCE---DINECLEDKSVCQRGDCINTAGSYD 858
Query: 73 CGKCPSGFH-GNGVECYRIS-CR-ANTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQCQ 127
C CP GF + C I+ C C C T+ C C G+ DGR C+
Sbjct: 859 C-TCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHC-VCQQGFSISADGRTCE 916
Query: 128 HV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLV 183
+ C C C +T+ + C C G+Q +G CVD++EC+L+
Sbjct: 917 DIDECVNNTVCDSHGFC--DNTAGSFRCL-CYQGFQAPQDGQGCVDVNECELLSGVCGEA 973
Query: 184 SCRNEE 189
C N E
Sbjct: 974 FCENVE 979
Score = 39.5 bits (88), Expect = 0.046
Identities = 35/138 (25%), Positives = 51/138 (36%), Gaps = 10/138 (7%)
Query: 25 VDTDQGF-RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
V T GF +C++CP + G C CQD+ + + Q G CP+G N
Sbjct: 259 VGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQ-GVCPNGECLN 317
Query: 84 GVECYRISCR----ANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRE 139
+ YR +C+ + F + + G C V GRQC H +
Sbjct: 318 TMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPC-YRLVSSGRQCMHPLSVHL---TK 373
Query: 140 RRCMPKSTSPYYECEGCP 157
+ C CE CP
Sbjct: 374 QLCCCSVGKAGPHCEKCP 391
Score = 39.5 bits (88), Expect = 0.046
Identities = 48/176 (27%), Positives = 66/176 (37%), Gaps = 32/176 (18%)
Query: 151 YECEGCPSGYQWNGYT--CVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWR 208
Y C C GY+++ CVD+DEC ++ C N E +G
Sbjct: 569 YTCI-CYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEG-- 625
Query: 209 GTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVN 268
+C+DVDEC C G CVNT G++ C C Y +
Sbjct: 626 --------TNCIDVDECLRPDV-CGEGH-CVNT-----------VGAFRCEYCDSGYRMT 664
Query: 269 TTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCV-CNTGWTG-NGTVCGLDRDLD 321
C D D + +PS C V G +CV C G+ G NG +D L+
Sbjct: 665 QRGRCEDIDECL---NPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE 717
Score = 39.1 bits (87), Expect = 0.061
Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 26/130 (20%)
Query: 205 QGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGH 264
+G+R + +R+ CVD+DEC + C +GR C NT +GS++C+ G
Sbjct: 575 EGYRFSEQQRK---CVDIDECTQVQHLCSQGR-CENT-----------EGSFLCICPAGF 619
Query: 265 YYVNTTRPCFDPDSLVKR--CDPSYCRRFNAVCGFGQKC-VCNTGW--TGNGTVCGLDRD 319
C D D ++ C +C N V F +C C++G+ T G +D
Sbjct: 620 MASEEGTNCIDVDECLRPDVCGEGHC--VNTVGAF--RCEYCDSGYRMTQRGRCEDIDEC 675
Query: 320 LDGH--PDEQ 327
L+ PDEQ
Sbjct: 676 LNPSTCPDEQ 685
>AC019127-1|AAY24260.1| 697|Homo sapiens unknown protein.
Length = 697
Score = 81.0 bits (191), Expect = 2e-14
Identities = 89/314 (28%), Positives = 125/314 (39%), Gaps = 54/314 (17%)
Query: 18 LCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSA-NPCFGGRVPCQDLPDGRYQCGK 75
+C CV+T FRCE C G + + C NP C + P G YQC
Sbjct: 93 VCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSP-GSYQCVP 151
Query: 76 CPSGFHGNGVECYRIS-C-RANTCFQGVSCEETQYGPKCGSCPTGYVG--DGRQCQHVCD 131
C GF G +C + C N C G C + C SC GY D + C+ + +
Sbjct: 152 CTEGFRGWNGQCLDVDECLEPNVCANG-DCSNLEGSYMC-SCHKGYTRTPDHKHCRDIDE 209
Query: 132 AQKP--CGRERRCMPKSTSPYYECEGCPSGYQWNGYT--CVDMDECDLIRPCDDLVSCRN 187
Q+ C + C K+T + C C GYQ + C D+DEC C CRN
Sbjct: 210 CQQGNLCVNGQ-C--KNTEGSFRCT-CGQGYQLSAAKDQCEDIDECQHRHLCAH-GQCRN 264
Query: 188 EEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSN 247
E QG+R +G +HC D++EC + ++ C RG C+NT
Sbjct: 265 TEGSFQCVC-------DQGYRASG---LGDHCEDINECLEDKSVCQRGD-CINT------ 307
Query: 248 PVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCD-PSYC----RRFNAVCGFGQKCV 302
GSY C C + ++ + C D + C+ P C N F CV
Sbjct: 308 -----AGSYDCT-CPDGFQLDDNKTCQD----INECEHPGLCGPQGECLNTEGSF--HCV 355
Query: 303 CNTGW--TGNGTVC 314
C G+ + +G C
Sbjct: 356 CQQGFSISADGRTC 369
Score = 61.3 bits (142), Expect = 1e-08
Identities = 55/184 (29%), Positives = 85/184 (46%), Gaps = 23/184 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQT-CRTA--CS-ANPCFGGRVPCQDLPDGRYQC 73
LCV +C +T+ FRC G Q S + C C + C G+ C++ +G +QC
Sbjct: 215 LCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQ--CRNT-EGSFQC 271
Query: 74 GKCPSGFHGNGV--ECYRIS-CRAN--TCFQGVSCEETQYGPKCGSCPTGY-VGDGRQCQ 127
C G+ +G+ C I+ C + C +G C T C +CP G+ + D + CQ
Sbjct: 272 -VCDQGYRASGLGDHCEDINECLEDKSVCQRG-DCINTAGSYDC-TCPDGFQLDDNKTCQ 328
Query: 128 HVCDAQKP--CGRERRCMPKSTSPYYECEGCPSGYQWN--GYTCVDMDECDLIRPCDDLV 183
+ + + P CG + C+ +T + C C G+ + G TC D+DEC CD
Sbjct: 329 DINECEHPGLCGPQGECL--NTEGSFHCV-CQQGFSISADGRTCEDIDECVNNTVCDSHG 385
Query: 184 SCRN 187
C N
Sbjct: 386 FCDN 389
Score = 50.8 bits (116), Expect = 2e-05
Identities = 53/186 (28%), Positives = 75/186 (40%), Gaps = 22/186 (11%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSD-GQTCRTACSANPCFGGRVPCQ--DLPD--GRYQ 72
LC +C +T+ F+C G + S G C N C + CQ D + G Y
Sbjct: 256 LCAHGQCRNTEGSFQCVCDQGYRASGLGDHCE---DINECLEDKSVCQRGDCINTAGSYD 312
Query: 73 CGKCPSGFH-GNGVECYRIS-CR-ANTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQCQ 127
C CP GF + C I+ C C C T+ C C G+ DGR C+
Sbjct: 313 C-TCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHC-VCQQGFSISADGRTCE 370
Query: 128 HV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLV 183
+ C C C +T+ + C C G+Q +G CVD++EC+L+
Sbjct: 371 DIDECVNNTVCDSHGFC--DNTAGSFRCL-CYQGFQAPQDGQGCVDVNECELLSGVCGEA 427
Query: 184 SCRNEE 189
C N E
Sbjct: 428 FCENVE 433
Score = 39.5 bits (88), Expect = 0.046
Identities = 48/176 (27%), Positives = 66/176 (37%), Gaps = 32/176 (18%)
Query: 151 YECEGCPSGYQWNGYT--CVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWR 208
Y C C GY+++ CVD+DEC ++ C N E +G
Sbjct: 23 YTCI-CYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEG-- 79
Query: 209 GTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVN 268
+C+DVDEC C G CVNT G++ C C Y +
Sbjct: 80 --------TNCIDVDECLRPDV-CGEGH-CVNT-----------VGAFRCEYCDSGYRMT 118
Query: 269 TTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCV-CNTGWTG-NGTVCGLDRDLD 321
C D D + +PS C V G +CV C G+ G NG +D L+
Sbjct: 119 QRGRCEDIDECL---NPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE 171
Score = 39.1 bits (87), Expect = 0.061
Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 26/130 (20%)
Query: 205 QGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGH 264
+G+R + +R+ CVD+DEC + C +GR C NT +GS++C+ G
Sbjct: 29 EGYRFSEQQRK---CVDIDECTQVQHLCSQGR-CENT-----------EGSFLCICPAGF 73
Query: 265 YYVNTTRPCFDPDSLVKR--CDPSYCRRFNAVCGFGQKC-VCNTGW--TGNGTVCGLDRD 319
C D D ++ C +C N V F +C C++G+ T G +D
Sbjct: 74 MASEEGTNCIDVDECLRPDVCGEGHC--VNTVGAF--RCEYCDSGYRMTQRGRCEDIDEC 129
Query: 320 LDGH--PDEQ 327
L+ PDEQ
Sbjct: 130 LNPSTCPDEQ 139
>AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming growth
factor beta binding protein 1 isoform LTBP-1S varian
protein.
Length = 1348
Score = 81.0 bits (191), Expect = 2e-14
Identities = 89/314 (28%), Positives = 125/314 (39%), Gaps = 54/314 (17%)
Query: 18 LCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSA-NPCFGGRVPCQDLPDGRYQCGK 75
+C CV+T FRCE C G + + C NP C + P G YQC
Sbjct: 593 VCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSP-GSYQCVP 651
Query: 76 CPSGFHGNGVECYRIS-C-RANTCFQGVSCEETQYGPKCGSCPTGYVG--DGRQCQHVCD 131
C GF G +C + C N C G C + C SC GY D + C+ + +
Sbjct: 652 CTEGFRGWNGQCLDVDECLEPNVCANG-DCSNLEGSYMC-SCHKGYTRTPDHKHCRDIDE 709
Query: 132 AQKP--CGRERRCMPKSTSPYYECEGCPSGYQWNGYT--CVDMDECDLIRPCDDLVSCRN 187
Q+ C + C K+T + C C GYQ + C D+DEC C CRN
Sbjct: 710 CQQGNLCVNGQ-C--KNTEGSFRCT-CGQGYQLSAAKDQCEDIDECQHRHLCAH-GQCRN 764
Query: 188 EEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSN 247
E QG+R +G +HC D++EC + ++ C RG C+NT
Sbjct: 765 TEGSFQCVC-------DQGYRASG---LGDHCEDINECLEDKSVCQRGD-CINT------ 807
Query: 248 PVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCD-PSYC----RRFNAVCGFGQKCV 302
GSY C C + ++ + C D + C+ P C N F CV
Sbjct: 808 -----AGSYDCT-CPDGFQLDDNKTCQD----INECEHPGLCGPQGECLNTEGSF--HCV 855
Query: 303 CNTGW--TGNGTVC 314
C G+ + +G C
Sbjct: 856 CQQGFSISADGRTC 869
Score = 61.3 bits (142), Expect = 1e-08
Identities = 55/184 (29%), Positives = 85/184 (46%), Gaps = 23/184 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQT-CRTA--CS-ANPCFGGRVPCQDLPDGRYQC 73
LCV +C +T+ FRC G Q S + C C + C G+ C++ +G +QC
Sbjct: 715 LCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQ--CRNT-EGSFQC 771
Query: 74 GKCPSGFHGNGV--ECYRIS-CRAN--TCFQGVSCEETQYGPKCGSCPTGY-VGDGRQCQ 127
C G+ +G+ C I+ C + C +G C T C +CP G+ + D + CQ
Sbjct: 772 -VCDQGYRASGLGDHCEDINECLEDKSVCQRG-DCINTAGSYDC-TCPDGFQLDDNKTCQ 828
Query: 128 HVCDAQKP--CGRERRCMPKSTSPYYECEGCPSGYQWN--GYTCVDMDECDLIRPCDDLV 183
+ + + P CG + C+ +T + C C G+ + G TC D+DEC CD
Sbjct: 829 DINECEHPGLCGPQGECL--NTEGSFHCV-CQQGFSISADGRTCEDIDECVNNTVCDSHG 885
Query: 184 SCRN 187
C N
Sbjct: 886 FCDN 889
Score = 50.8 bits (116), Expect = 2e-05
Identities = 53/186 (28%), Positives = 75/186 (40%), Gaps = 22/186 (11%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSD-GQTCRTACSANPCFGGRVPCQ--DLPD--GRYQ 72
LC +C +T+ F+C G + S G C N C + CQ D + G Y
Sbjct: 756 LCAHGQCRNTEGSFQCVCDQGYRASGLGDHCE---DINECLEDKSVCQRGDCINTAGSYD 812
Query: 73 CGKCPSGFH-GNGVECYRIS-CR-ANTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQCQ 127
C CP GF + C I+ C C C T+ C C G+ DGR C+
Sbjct: 813 C-TCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHC-VCQQGFSISADGRTCE 870
Query: 128 HV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLV 183
+ C C C +T+ + C C G+Q +G CVD++EC+L+
Sbjct: 871 DIDECVNNTVCDSHGFC--DNTAGSFRCL-CYQGFQAPQDGQGCVDVNECELLSGVCGEA 927
Query: 184 SCRNEE 189
C N E
Sbjct: 928 FCENVE 933
Score = 40.3 bits (90), Expect = 0.026
Identities = 35/138 (25%), Positives = 52/138 (37%), Gaps = 9/138 (6%)
Query: 25 VDTDQGF-RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
V T GF +C++CP + G C CQD+ + + Q G CP+G N
Sbjct: 265 VGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQ-GVCPNGECLN 323
Query: 84 GVECYRISCR----ANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRE 139
+ YR +C+ + F + + G C V GRQC H ++
Sbjct: 324 TMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPC-YRLVSSGRQCMHPLSVH--LTKQ 380
Query: 140 RRCMPKSTSPYYECEGCP 157
C + CE CP
Sbjct: 381 LCCCSVGKAWGPHCEKCP 398
Score = 39.5 bits (88), Expect = 0.046
Identities = 48/176 (27%), Positives = 66/176 (37%), Gaps = 32/176 (18%)
Query: 151 YECEGCPSGYQWNGYT--CVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWR 208
Y C C GY+++ CVD+DEC ++ C N E +G
Sbjct: 523 YTCI-CYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEG-- 579
Query: 209 GTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVN 268
+C+DVDEC C G CVNT G++ C C Y +
Sbjct: 580 --------TNCIDVDECLRPDV-CGEGH-CVNT-----------VGAFRCEYCDSGYRMT 618
Query: 269 TTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCV-CNTGWTG-NGTVCGLDRDLD 321
C D D + +PS C V G +CV C G+ G NG +D L+
Sbjct: 619 QRGRCEDIDECL---NPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE 671
Score = 39.1 bits (87), Expect = 0.061
Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 26/130 (20%)
Query: 205 QGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGH 264
+G+R + +R+ CVD+DEC + C +GR C NT +GS++C+ G
Sbjct: 529 EGYRFSEQQRK---CVDIDECTQVQHLCSQGR-CENT-----------EGSFLCICPAGF 573
Query: 265 YYVNTTRPCFDPDSLVKR--CDPSYCRRFNAVCGFGQKC-VCNTGW--TGNGTVCGLDRD 319
C D D ++ C +C N V F +C C++G+ T G +D
Sbjct: 574 MASEEGTNCIDVDECLRPDVCGEGHC--VNTVGAF--RCEYCDSGYRMTQRGRCEDIDEC 629
Query: 320 LDGH--PDEQ 327
L+ PDEQ
Sbjct: 630 LNPSTCPDEQ 639
>D86566-1|BAA13116.1| 955|Homo sapiens notch related protein
protein.
Length = 955
Score = 80.2 bits (189), Expect = 3e-14
Identities = 56/153 (36%), Positives = 73/153 (47%), Gaps = 20/153 (13%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C + G+ C CP S T G C+T+ C + PCF G C + P G + C C
Sbjct: 741 GGSCNPSPGGYYCT-CPPSHT--GPQCQTSTDYCVSAPCFNGGT-CVNRP-GTFSC-LCA 794
Query: 78 SGFHGNGVEC-YRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQK 134
GF G E R SC + C +C+++ GP+C CPTGY G CQ + D AQ+
Sbjct: 795 MGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC-LCPTGYTGG--SCQTLMDLCAQR 851
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC 167
PC R C+ T P + C C G W G C
Sbjct: 852 PCPRNSHCL--QTGPSFHCL-CLQG--WTGPLC 879
Score = 57.2 bits (132), Expect = 2e-07
Identities = 47/168 (27%), Positives = 67/168 (39%), Gaps = 15/168 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C++T F C PG S + C + PC G C DL + C CP G
Sbjct: 449 GGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGST-CLDLL-ATFHC-LCPPGL 505
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C + C C + G +C C G+ G +C+ D PC
Sbjct: 506 EGQLCEVETNECASAPCLNHADCHDLLNGFQC-ICLPGF--SGTRCEEDIDECRSSPCAN 562
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSC 185
+C + + + C+ C G++ G C ++DEC L PC SC
Sbjct: 563 GGQCQDQPGA--FHCK-CLPGFE--GPRCQTEVDEC-LSDPCPVGASC 604
Score = 56.8 bits (131), Expect = 3e-07
Identities = 79/285 (27%), Positives = 108/285 (37%), Gaps = 46/285 (16%)
Query: 32 RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS 91
+C PG T + R CSANPC G V P + QC CP GF G+ E
Sbjct: 142 QCSCMPG-WTGEQCQLRDFCSANPCVNGGVCLATYP--QIQC-HCPPGFEGHACERDVNE 197
Query: 92 C--RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRC--MPKST 147
C C +G SC T +C CP G G + + + C C MP+
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKD 256
Query: 148 SPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQG 206
S ++ C CP G+ G C V+ D C + C + +C++ +
Sbjct: 257 STFHLCL-CPPGF--IGPDCEVNPDNC-VSHQCQNGGTCQD-------GLDTYTCLCPET 305
Query: 207 WRGTGNERRREHCVDVDEC-ADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHY 265
W G + DVDEC G +C G C N+ GS+ CV C +
Sbjct: 306 WTGW------DCSEDVDECETQGPPHCRNGGTCQNS-----------AGSFHCV-CVSGW 347
Query: 266 YVNTTRPCFDPDSLVKRCDP-SYCRRFNAVCGFGQKCVCNTGWTG 309
+ D D + C P S C + V F C+C G TG
Sbjct: 348 GGTSCEENLD-DCIAATCAPGSTC--IDRVGSF--SCLCPPGRTG 387
Score = 53.6 bits (123), Expect = 3e-06
Identities = 60/194 (30%), Positives = 74/194 (38%), Gaps = 41/194 (21%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G +C D F C+ PG + QT C ++PC G C DLP G + C CPSGF
Sbjct: 563 GGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVG-ASCLDLP-GAFFC-LCPSGF 619
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-----DGRQCQH------- 128
G C C N C C++ + C CP G G D C H
Sbjct: 620 --TGQLCEVPLCAPNLCQPKQICKDQKDKANC-LCPDGSPGCAPPEDNCTCHHGHCQRSS 676
Query: 129 -VCDA---------------QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMD 171
VCD PC C P+ + Y C CP+GY G TC +M
Sbjct: 677 CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG--YNCT-CPTGY--TGPTCSEEMT 731
Query: 172 ECDLIRPCDDLVSC 185
C PC + SC
Sbjct: 732 ACH-SGPCLNGGSC 744
Score = 50.4 bits (115), Expect = 2e-05
Identities = 46/160 (28%), Positives = 65/160 (40%), Gaps = 15/160 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA-CSANPCFGGRVPCQDLP--DGRYQCGKCP 77
G C +T F+C CP Q R C C G CQ +P D + CP
Sbjct: 208 GTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGT-CQLMPEKDSTFHLCLCP 265
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-DGRQCQHVCDAQKP- 135
GF G E +C ++ C G +C++ C CP + G D + C+ Q P
Sbjct: 266 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTC-LCPETWTGWDCSEDVDECETQGPP 324
Query: 136 -CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDEC 173
C C + S + C C SG W G +C + +D+C
Sbjct: 325 HCRNGGTCQNSAGS--FHCV-CVSG--WGGTSCEENLDDC 359
Score = 49.6 bits (113), Expect = 4e-05
Identities = 53/177 (29%), Positives = 73/177 (41%), Gaps = 20/177 (11%)
Query: 21 GERCVDTDQGFRCERCPGSQTS-----DGQTCRTACSANPCFGGRVPCQDLPDGRYQCGK 75
G C D + C CP + T D C T + GG CQ+ G + C
Sbjct: 288 GGTCQDGLDTYTC-LCPETWTGWDCSEDVDECETQGPPHCRNGGT--CQNSA-GSFHC-V 342
Query: 76 CPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
C SG+ G E C A TC G +C + C CP G G + +C +Q P
Sbjct: 343 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSC-LCPPGRTGLLCHLEDMCLSQ-P 400
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIR----PCDDLVSCRN 187
C + +C ST+P C ++G TC D+DEC + + PC+ SC N
Sbjct: 401 CHGDAQC---STNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLN 454
Score = 47.2 bits (107), Expect = 2e-04
Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 11/113 (9%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGP 110
C + PC G C P G Y C CP+G+ G +C + C G SC + G
Sbjct: 695 CISAPCAHGGT-CYPQPSG-YNC-TCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGY 751
Query: 111 KCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQ 161
C +CP + G QCQ D PC C+ + + + C C G+Q
Sbjct: 752 YC-TCPPSHTGP--QCQTSTDYCVSAPCFNGGTCVNRPGT--FSCL-CAMGFQ 798
Score = 45.6 bits (103), Expect = 7e-04
Identities = 48/182 (26%), Positives = 69/182 (37%), Gaps = 16/182 (8%)
Query: 14 TPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGRVPCQDLPDG--- 69
T L +G+ GF E C + Q C+ S + P
Sbjct: 40 TCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTP 99
Query: 70 RYQCGKCPSGFHGNGVECY-RISCRANTCFQGVSCEETQYG-PKCGSCPTGYVGDGRQCQ 127
+ C C GF G + C + C + C G P+C SC G+ G+ Q +
Sbjct: 100 SFLC-TCLPGFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQC-SCMPGWTGEQCQLR 157
Query: 128 HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDEC-DLIRPCDDLVSC 185
C A PC C+ +T P +C CP G++ G+ C D++EC PC SC
Sbjct: 158 DFCSA-NPCVNGGVCL--ATYPQIQCH-CPPGFE--GHACERDVNECFQDPGPCPKGTSC 211
Query: 186 RN 187
N
Sbjct: 212 HN 213
Score = 31.9 bits (69), Expect = 9.2
Identities = 19/53 (35%), Positives = 22/53 (41%), Gaps = 2/53 (3%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQC 73
G CVD+ + C PG Q S Q C + PC G C P G Y C
Sbjct: 904 GGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNG-ATCMAQPSG-YLC 954
>AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 79.8 bits (188), Expect = 4e-14
Identities = 76/256 (29%), Positives = 104/256 (40%), Gaps = 28/256 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C + G+ C CP S T G C+T+ C + PCF G C + P G + C C
Sbjct: 741 GGSCNPSPGGYYCT-CPPSHT--GPQCQTSTDYCVSAPCFNGGT-CVNRP-GTFSC-LCA 794
Query: 78 SGFHGNGVEC-YRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQK 134
GF G E R SC + C +C+++ GP+C CPT Y G CQ + D AQK
Sbjct: 795 MGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC-LCPTVYTGGS--CQTLMDLCAQK 851
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECD--LIRPCDDLVSCRNEEXX 191
PC R C+ T P + C C G W G C + + C + D+ S +
Sbjct: 852 PCPRNSHCL--QTGPSFHCL-CLQG--WTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGL 906
Query: 192 XXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC---PRGRLCVNTPQYPSNP 248
G++G+ + C + C +G A C P G LC P Y
Sbjct: 907 CVDSGPSYFCHCPPGFQGSLCQDHVNPC-ESRPCQNG-ATCMAQPSGYLCQCAPGYDGQN 964
Query: 249 VSSLQGSYICVPCGGH 264
S + PC H
Sbjct: 965 CSKELDACQSQPCHNH 980
Score = 57.2 bits (132), Expect = 2e-07
Identities = 47/168 (27%), Positives = 67/168 (39%), Gaps = 15/168 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C++T F C PG S + C + PC G C DL + C CP G
Sbjct: 449 GGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGST-CLDLL-ATFHC-LCPPGL 505
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C + C C + G +C C G+ G +C+ D PC
Sbjct: 506 EGQLCEVETNECASAPCLNHADCHDLLNGFQC-ICLPGF--SGTRCEEDIDECRSSPCAN 562
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSC 185
+C + + + C+ C G++ G C ++DEC L PC SC
Sbjct: 563 GGQCQDQPGA--FHCK-CLPGFE--GPRCQTEVDEC-LSDPCPVGASC 604
Score = 56.8 bits (131), Expect = 3e-07
Identities = 79/285 (27%), Positives = 108/285 (37%), Gaps = 46/285 (16%)
Query: 32 RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS 91
+C PG T + R CSANPC G V P + QC CP GF G+ E
Sbjct: 142 QCSCMPG-WTGEQCQLRDFCSANPCVNGGVCLATYP--QIQC-HCPPGFEGHACERDVNE 197
Query: 92 C--RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRC--MPKST 147
C C +G SC T +C CP G G + + + C C MP+
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKD 256
Query: 148 SPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQG 206
S ++ C CP G+ G C V+ D C + C + +C++ +
Sbjct: 257 STFHLCL-CPPGF--IGPDCEVNPDNC-VSHQCQNGGTCQD-------GLDTYTCLCPET 305
Query: 207 WRGTGNERRREHCVDVDEC-ADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHY 265
W G + DVDEC G +C G C N+ GS+ CV C +
Sbjct: 306 WTGW------DCSEDVDECETQGPPHCRNGGTCQNS-----------AGSFHCV-CVSGW 347
Query: 266 YVNTTRPCFDPDSLVKRCDP-SYCRRFNAVCGFGQKCVCNTGWTG 309
+ D D + C P S C + V F C+C G TG
Sbjct: 348 GGTSCEENLD-DCIAATCAPGSTC--IDRVGSF--SCLCPPGRTG 387
Score = 56.0 bits (129), Expect = 5e-07
Identities = 39/112 (34%), Positives = 50/112 (44%), Gaps = 13/112 (11%)
Query: 71 YQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVC 130
Y C CP GF G+ + + C + C G +C G C C GY DG+ C
Sbjct: 914 YFC-HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLC-QCAPGY--DGQNCSKEL 969
Query: 131 DA--QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPC 179
DA +PC C PK + C CP G+ G C D+DEC L +PC
Sbjct: 970 DACQSQPCHNHGTCTPKPGG--FHC-ACPPGFV--GLRCEGDVDEC-LDQPC 1015
Score = 53.6 bits (123), Expect = 3e-06
Identities = 60/194 (30%), Positives = 74/194 (38%), Gaps = 41/194 (21%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G +C D F C+ PG + QT C ++PC G C DLP G + C CPSGF
Sbjct: 563 GGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVG-ASCLDLP-GAFFC-LCPSGF 619
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-----DGRQCQH------- 128
G C C N C C++ + C CP G G D C H
Sbjct: 620 --TGQLCEVPLCAPNLCQPKQICKDQKDKANC-LCPDGSPGCAPPEDNCTCHHGHCQRSS 676
Query: 129 -VCDA---------------QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMD 171
VCD PC C P+ + Y C CP+GY G TC +M
Sbjct: 677 CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG--YNCT-CPTGY--TGPTCSEEMT 731
Query: 172 ECDLIRPCDDLVSC 185
C PC + SC
Sbjct: 732 ACH-SGPCLNGGSC 744
Score = 50.4 bits (115), Expect = 2e-05
Identities = 46/160 (28%), Positives = 65/160 (40%), Gaps = 15/160 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA-CSANPCFGGRVPCQDLP--DGRYQCGKCP 77
G C +T F+C CP Q R C C G CQ +P D + CP
Sbjct: 208 GTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGT-CQLMPEKDSTFHLCLCP 265
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-DGRQCQHVCDAQKP- 135
GF G E +C ++ C G +C++ C CP + G D + C+ Q P
Sbjct: 266 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTC-LCPETWTGWDCSEDVDECETQGPP 324
Query: 136 -CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDEC 173
C C + S + C C SG W G +C + +D+C
Sbjct: 325 HCRNGGTCQNSAGS--FHCV-CVSG--WGGTSCEENLDDC 359
Score = 49.6 bits (113), Expect = 4e-05
Identities = 53/177 (29%), Positives = 73/177 (41%), Gaps = 20/177 (11%)
Query: 21 GERCVDTDQGFRCERCPGSQTS-----DGQTCRTACSANPCFGGRVPCQDLPDGRYQCGK 75
G C D + C CP + T D C T + GG CQ+ G + C
Sbjct: 288 GGTCQDGLDTYTC-LCPETWTGWDCSEDVDECETQGPPHCRNGGT--CQNSA-GSFHC-V 342
Query: 76 CPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
C SG+ G E C A TC G +C + C CP G G + +C +Q P
Sbjct: 343 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSC-LCPPGRTGLLCHLEDMCLSQ-P 400
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIR----PCDDLVSCRN 187
C + +C ST+P C ++G TC D+DEC + + PC+ SC N
Sbjct: 401 CHGDAQC---STNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLN 454
Score = 47.2 bits (107), Expect = 2e-04
Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 11/113 (9%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGP 110
C + PC G C P G Y C CP+G+ G +C + C G SC + G
Sbjct: 695 CISAPCAHGGT-CYPQPSG-YNC-TCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGY 751
Query: 111 KCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQ 161
C +CP + G QCQ D PC C+ + + + C C G+Q
Sbjct: 752 YC-TCPPSHTGP--QCQTSTDYCVSAPCFNGGTCVNRPGT--FSCL-CAMGFQ 798
Score = 45.6 bits (103), Expect = 7e-04
Identities = 48/182 (26%), Positives = 69/182 (37%), Gaps = 16/182 (8%)
Query: 14 TPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGRVPCQDLPDG--- 69
T L +G+ GF E C + Q C+ S + P
Sbjct: 40 TCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTP 99
Query: 70 RYQCGKCPSGFHGNGVEC-YRISCRANTCFQGVSCEETQYG-PKCGSCPTGYVGDGRQCQ 127
+ C C GF G + C + C + C G P+C SC G+ G+ Q +
Sbjct: 100 SFLC-TCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQC-SCMPGWTGEQCQLR 157
Query: 128 HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDEC-DLIRPCDDLVSC 185
C A PC C+ +T P +C CP G++ G+ C D++EC PC SC
Sbjct: 158 DFCSA-NPCVNGGVCL--ATYPQIQCH-CPPGFE--GHACERDVNECFQDPGPCPKGTSC 211
Query: 186 RN 187
N
Sbjct: 212 HN 213
Score = 44.8 bits (101), Expect = 0.001
Identities = 39/142 (27%), Positives = 49/142 (34%), Gaps = 9/142 (6%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFG-GRVPCQDLPDGRYQCGKCPSGFHG 82
C GF C PG + C PC G C L + Y C +C G G
Sbjct: 983 CTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFY-C-QCLPGHTG 1040
Query: 83 NGVECYRISCRANTCFQGVSCEETQYGPK--CGSCPTGYVGDGRQCQHVCDA--QKPCGR 138
E C + CF G +CE T P CP G+ +G C H + C
Sbjct: 1041 QWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGF--EGPTCSHRAPSCGFHHCHH 1098
Query: 139 ERRCMPKSTSPYYECEGCPSGY 160
C+P + C SGY
Sbjct: 1099 GGLCLPSPKPGFPPRCACLSGY 1120
>AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 79.8 bits (188), Expect = 4e-14
Identities = 76/256 (29%), Positives = 104/256 (40%), Gaps = 28/256 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C + G+ C CP S T G C+T+ C + PCF G C + P G + C C
Sbjct: 741 GGSCNPSPGGYYCT-CPPSHT--GPQCQTSTDYCVSAPCFNGGT-CVNRP-GTFSC-LCA 794
Query: 78 SGFHGNGVEC-YRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQK 134
GF G E R SC + C +C+++ GP+C CPT Y G CQ + D AQK
Sbjct: 795 MGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC-LCPTVYTGGS--CQTLMDLCAQK 851
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECD--LIRPCDDLVSCRNEEXX 191
PC R C+ T P + C C G W G C + + C + D+ S +
Sbjct: 852 PCPRNSHCL--QTGPSFHCL-CLQG--WTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGL 906
Query: 192 XXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC---PRGRLCVNTPQYPSNP 248
G++G+ + C + C +G A C P G LC P Y
Sbjct: 907 CVDSGPSYFCHCPPGFQGSLCQDHVNPC-ESRPCQNG-ATCMAQPSGYLCQCAPGYDGQN 964
Query: 249 VSSLQGSYICVPCGGH 264
S + PC H
Sbjct: 965 CSKELDACQSQPCHNH 980
Score = 57.2 bits (132), Expect = 2e-07
Identities = 47/168 (27%), Positives = 67/168 (39%), Gaps = 15/168 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C++T F C PG S + C + PC G C DL + C CP G
Sbjct: 449 GGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGST-CLDLL-ATFHC-LCPPGL 505
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C + C C + G +C C G+ G +C+ D PC
Sbjct: 506 EGQLCEVETNECASAPCLNHADCHDLLNGFQC-ICLPGF--SGTRCEEDIDECRSSPCAN 562
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSC 185
+C + + + C+ C G++ G C ++DEC L PC SC
Sbjct: 563 GGQCQDQPGA--FHCK-CLPGFE--GPRCQTEVDEC-LSDPCPVGASC 604
Score = 56.8 bits (131), Expect = 3e-07
Identities = 79/285 (27%), Positives = 108/285 (37%), Gaps = 46/285 (16%)
Query: 32 RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS 91
+C PG T + R CSANPC G V P + QC CP GF G+ E
Sbjct: 142 QCSCMPG-WTGEQCQLRDFCSANPCVNGGVCLATYP--QIQC-HCPPGFEGHACERDVNE 197
Query: 92 C--RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRC--MPKST 147
C C +G SC T +C CP G G + + + C C MP+
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKD 256
Query: 148 SPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQG 206
S ++ C CP G+ G C V+ D C + C + +C++ +
Sbjct: 257 STFHLCL-CPPGF--IGPDCEVNPDNC-VSHQCQNGGTCQD-------GLDTYTCLCPET 305
Query: 207 WRGTGNERRREHCVDVDEC-ADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHY 265
W G + DVDEC G +C G C N+ GS+ CV C +
Sbjct: 306 WTGW------DCSEDVDECETQGPPHCRNGGTCQNS-----------AGSFHCV-CVSGW 347
Query: 266 YVNTTRPCFDPDSLVKRCDP-SYCRRFNAVCGFGQKCVCNTGWTG 309
+ D D + C P S C + V F C+C G TG
Sbjct: 348 GGTSCEENLD-DCIAATCAPGSTC--IDRVGSF--SCLCPPGRTG 387
Score = 56.0 bits (129), Expect = 5e-07
Identities = 39/112 (34%), Positives = 50/112 (44%), Gaps = 13/112 (11%)
Query: 71 YQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVC 130
Y C CP GF G+ + + C + C G +C G C C GY DG+ C
Sbjct: 914 YFC-HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLC-QCAPGY--DGQNCSKEL 969
Query: 131 DA--QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPC 179
DA +PC C PK + C CP G+ G C D+DEC L +PC
Sbjct: 970 DACQSQPCHNHGTCTPKPGG--FHC-ACPPGFV--GLRCEGDVDEC-LDQPC 1015
Score = 53.6 bits (123), Expect = 3e-06
Identities = 60/194 (30%), Positives = 74/194 (38%), Gaps = 41/194 (21%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G +C D F C+ PG + QT C ++PC G C DLP G + C CPSGF
Sbjct: 563 GGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVG-ASCLDLP-GAFFC-LCPSGF 619
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-----DGRQCQH------- 128
G C C N C C++ + C CP G G D C H
Sbjct: 620 --TGQLCEVPLCAPNLCQPKQICKDQKDKANC-LCPDGSPGCAPPEDNCTCHHGHCQRSS 676
Query: 129 -VCDA---------------QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMD 171
VCD PC C P+ + Y C CP+GY G TC +M
Sbjct: 677 CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG--YNCT-CPTGY--TGPTCSEEMT 731
Query: 172 ECDLIRPCDDLVSC 185
C PC + SC
Sbjct: 732 ACH-SGPCLNGGSC 744
Score = 50.4 bits (115), Expect = 2e-05
Identities = 46/160 (28%), Positives = 65/160 (40%), Gaps = 15/160 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA-CSANPCFGGRVPCQDLP--DGRYQCGKCP 77
G C +T F+C CP Q R C C G CQ +P D + CP
Sbjct: 208 GTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGT-CQLMPEKDSTFHLCLCP 265
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-DGRQCQHVCDAQKP- 135
GF G E +C ++ C G +C++ C CP + G D + C+ Q P
Sbjct: 266 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTC-LCPETWTGWDCSEDVDECETQGPP 324
Query: 136 -CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDEC 173
C C + S + C C SG W G +C + +D+C
Sbjct: 325 HCRNGGTCQNSAGS--FHCV-CVSG--WGGTSCEENLDDC 359
Score = 49.6 bits (113), Expect = 4e-05
Identities = 53/177 (29%), Positives = 73/177 (41%), Gaps = 20/177 (11%)
Query: 21 GERCVDTDQGFRCERCPGSQTS-----DGQTCRTACSANPCFGGRVPCQDLPDGRYQCGK 75
G C D + C CP + T D C T + GG CQ+ G + C
Sbjct: 288 GGTCQDGLDTYTC-LCPETWTGWDCSEDVDECETQGPPHCRNGGT--CQNSA-GSFHC-V 342
Query: 76 CPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
C SG+ G E C A TC G +C + C CP G G + +C +Q P
Sbjct: 343 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSC-LCPPGRTGLLCHLEDMCLSQ-P 400
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIR----PCDDLVSCRN 187
C + +C ST+P C ++G TC D+DEC + + PC+ SC N
Sbjct: 401 CHGDAQC---STNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLN 454
Score = 47.2 bits (107), Expect = 2e-04
Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 11/113 (9%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGP 110
C + PC G C P G Y C CP+G+ G +C + C G SC + G
Sbjct: 695 CISAPCAHGGT-CYPQPSG-YNC-TCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGY 751
Query: 111 KCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQ 161
C +CP + G QCQ D PC C+ + + + C C G+Q
Sbjct: 752 YC-TCPPSHTGP--QCQTSTDYCVSAPCFNGGTCVNRPGT--FSCL-CAMGFQ 798
Score = 45.6 bits (103), Expect = 7e-04
Identities = 48/182 (26%), Positives = 69/182 (37%), Gaps = 16/182 (8%)
Query: 14 TPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGRVPCQDLPDG--- 69
T L +G+ GF E C + Q C+ S + P
Sbjct: 40 TCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTP 99
Query: 70 RYQCGKCPSGFHGNGVEC-YRISCRANTCFQGVSCEETQYG-PKCGSCPTGYVGDGRQCQ 127
+ C C GF G + C + C + C G P+C SC G+ G+ Q +
Sbjct: 100 SFLC-TCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQC-SCMPGWTGEQCQLR 157
Query: 128 HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDEC-DLIRPCDDLVSC 185
C A PC C+ +T P +C CP G++ G+ C D++EC PC SC
Sbjct: 158 DFCSA-NPCVNGGVCL--ATYPQIQCH-CPPGFE--GHACERDVNECFQDPGPCPKGTSC 211
Query: 186 RN 187
N
Sbjct: 212 HN 213
Score = 44.8 bits (101), Expect = 0.001
Identities = 39/142 (27%), Positives = 49/142 (34%), Gaps = 9/142 (6%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFG-GRVPCQDLPDGRYQCGKCPSGFHG 82
C GF C PG + C PC G C L + Y C +C G G
Sbjct: 983 CTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFY-C-QCLPGHTG 1040
Query: 83 NGVECYRISCRANTCFQGVSCEETQYGPK--CGSCPTGYVGDGRQCQHVCDA--QKPCGR 138
E C + CF G +CE T P CP G+ +G C H + C
Sbjct: 1041 QWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGF--EGPTCSHRAPSCGFHHCHH 1098
Query: 139 ERRCMPKSTSPYYECEGCPSGY 160
C+P + C SGY
Sbjct: 1099 GGLCLPSPKPGFPPRCACLSGY 1120
>Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein.
Length = 1223
Score = 78.2 bits (184), Expect = 1e-13
Identities = 57/175 (32%), Positives = 80/175 (45%), Gaps = 13/175 (7%)
Query: 15 PFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCG 74
P+ CV CV+ Q CE G D + S +PC G PD +Y+C
Sbjct: 262 PYPGCVHGSCVEPWQ-CNCETNWGGLLCD-KDLNYCGSHHPCTNGGTCINAEPD-QYRC- 317
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD-AQ 133
CP G+ G E +C +N C G SC E G +C CP+G+ G + + A
Sbjct: 318 TCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFEC-HCPSGWSGPTCASADIDECAS 376
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
PC C+ + +EC CP QW G TC +D +EC+ +PC + SC+N
Sbjct: 377 NPCAAGGTCVDQVDG--FECI-CPE--QWVGATCQLDANECE-GKPCLNAFSCKN 425
Score = 56.8 bits (131), Expect = 3e-07
Identities = 51/165 (30%), Positives = 68/165 (41%), Gaps = 21/165 (12%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA----CSANPCFGGRVPCQDLPDGRYQCGKC 76
G C + GF C CP + G TC +A C++NPC G C D DG ++C C
Sbjct: 343 GGSCHEVPSGFECH-CPSGWS--GPTCASADIDECASNPCAAGGT-CVDQVDG-FEC-IC 396
Query: 77 PSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQKP 135
P + G + C C SC+ G C C G+ G C +V D +
Sbjct: 397 PEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYC-DCIPGW--KGINCHINVNDCRGQ 453
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPC 179
C C K Y+C CP G+ G C ++ DEC PC
Sbjct: 454 CQHGGTC--KDLVNGYQCV-CPRGF--GGRHCELERDEC-ASSPC 492
Score = 56.4 bits (130), Expect = 4e-07
Identities = 46/151 (30%), Positives = 60/151 (39%), Gaps = 11/151 (7%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C + G+ C+ PG + + C GG C+DL +G YQC CP GF G
Sbjct: 423 CKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGT--CKDLVNG-YQC-VCPRGFGGR 478
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCM 143
E R C ++ C G CE+ G C CP G+ G + PC RC
Sbjct: 479 HCELERDECASSPCHSGGLCEDLADGFHC-HCPQGFSGPLCEVDVDLCEPSPCRNGARCY 537
Query: 144 PKSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
YY C CP + G C V + C
Sbjct: 538 -NLEGDYY-C-ACPDDF--GGKNCSVPREPC 563
Score = 56.4 bits (130), Expect = 4e-07
Identities = 48/164 (29%), Positives = 69/164 (42%), Gaps = 18/164 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C+D FRC CP +G+ C T C +PC R C DL + Y C C
Sbjct: 633 GGTCIDEVDAFRCF-CPSGW--EGELCDTNPNDCLPDPCHS-RGRCYDLVNDFY-CA-CD 686
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDG-RQCQHVCDAQKPC 136
G+ G C A TC G +C ++ +C +CP G+ G ++ PC
Sbjct: 687 DGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRC-ACPPGWKGSTCAVAKNSSCLPNPC 745
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPC 179
C+ S + C C G W G TC + ++C+ + PC
Sbjct: 746 VNGGTCVGSGAS--FSCI-CRDG--WEGRTCTHNTNDCNPL-PC 783
Score = 54.4 bits (125), Expect = 2e-06
Identities = 41/142 (28%), Positives = 61/142 (42%), Gaps = 13/142 (9%)
Query: 19 CV-GERCVDTDQGFRCERCPGSQTSDGQTCR---TACSANPCFGGRVPCQDLPDGRYQCG 74
CV G CV + F C G + G+TC C+ PC+ G + C D + ++C
Sbjct: 745 CVNGGTCVGSGASFSCICRDGWE---GRTCTHNTNDCNPLPCYNGGI-CVDGVNW-FRC- 798
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQK 134
+C GF G C+++ C G +C + G +C SCP G G +CQ V +
Sbjct: 799 ECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRC-SCPPGRAGP--RCQEVIGFGR 855
Query: 135 PCGRERRCMPKSTSPYYECEGC 156
C P +S +C C
Sbjct: 856 SCWSRGTPFPHGSSWVEDCNSC 877
Score = 43.2 bits (97), Expect = 0.004
Identities = 36/118 (30%), Positives = 48/118 (40%), Gaps = 9/118 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G CVD FRCE PG D + C ++PC G C D +G Y+C CP G
Sbjct: 786 GGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYG-ATCVDEING-YRC-SCPPG- 841
Query: 81 HGNGVECYRISCRANTCF-QGVSCEE-TQYGPKCGSCPTGYVGDGRQCQHVCDAQKPC 136
G C + +C+ +G + + C SC + R C V KPC
Sbjct: 842 -RAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRC--LDGRRDCSKVWCGWKPC 896
>AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein.
Length = 1238
Score = 77.8 bits (183), Expect = 1e-13
Identities = 59/176 (33%), Positives = 80/176 (45%), Gaps = 16/176 (9%)
Query: 15 PFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCG 74
P+ CV CV+ Q CE G D + S +PC G PD +Y+C
Sbjct: 278 PYPGCVHGSCVEPWQ-CNCETNWGGLLCD-KDLNYCGSHHPCTNGGTCINAEPD-QYRC- 333
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--A 132
CP G+ G E +C +N C G SC E G +C CP+G+ G C D A
Sbjct: 334 TCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFEC-HCPSGW--SGPTCALDIDECA 390
Query: 133 QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
PC C+ + +EC CP QW G TC +D +EC+ +PC + SC+N
Sbjct: 391 SNPCAAGGTCVDQVDG--FECI-CPE--QWVGATCQLDANECE-GKPCLNAFSCKN 440
Score = 56.4 bits (130), Expect = 4e-07
Identities = 46/151 (30%), Positives = 60/151 (39%), Gaps = 11/151 (7%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C + G+ C+ PG + + C GG C+DL +G YQC CP GF G
Sbjct: 438 CKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGT--CKDLVNG-YQC-VCPRGFGGR 493
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCM 143
E R C ++ C G CE+ G C CP G+ G + PC RC
Sbjct: 494 HCELERDECASSPCHSGGLCEDLADGFHC-HCPQGFSGPLCEVDVDLCEPSPCRNGARCY 552
Query: 144 PKSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
YY C CP + G C V + C
Sbjct: 553 -NLEGDYY-C-ACPDDF--GGKNCSVPREPC 578
Score = 56.4 bits (130), Expect = 4e-07
Identities = 48/164 (29%), Positives = 69/164 (42%), Gaps = 18/164 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C+D FRC CP +G+ C T C +PC R C DL + Y C C
Sbjct: 648 GGTCIDEVDAFRCF-CPSGW--EGELCDTNPNDCLPDPCHS-RGRCYDLVNDFY-CA-CD 701
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDG-RQCQHVCDAQKPC 136
G+ G C A TC G +C ++ +C +CP G+ G ++ PC
Sbjct: 702 DGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRC-ACPPGWKGSTCAVAKNSSCLPNPC 760
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPC 179
C+ S + C C G W G TC + ++C+ + PC
Sbjct: 761 VNGGTCVGSGAS--FSCI-CRDG--WEGRTCTHNTNDCNPL-PC 798
Score = 54.8 bits (126), Expect = 1e-06
Identities = 50/164 (30%), Positives = 66/164 (40%), Gaps = 20/164 (12%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRT---ACSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C + GF C CP + G TC C++NPC G C D DG ++C CP
Sbjct: 359 GGSCHEVPSGFECH-CPSGWS--GPTCALDIDECASNPCAAGGT-CVDQVDG-FEC-ICP 412
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQKPC 136
+ G + C C SC+ G C C G+ G C +V D + C
Sbjct: 413 EQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYC-DCIPGW--KGINCHINVNDCRGQC 469
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPC 179
C K Y+C CP G+ G C ++ DEC PC
Sbjct: 470 QHGGTC--KDLVNGYQCV-CPRGF--GGRHCELERDEC-ASSPC 507
Score = 54.4 bits (125), Expect = 2e-06
Identities = 41/142 (28%), Positives = 61/142 (42%), Gaps = 13/142 (9%)
Query: 19 CV-GERCVDTDQGFRCERCPGSQTSDGQTCR---TACSANPCFGGRVPCQDLPDGRYQCG 74
CV G CV + F C G + G+TC C+ PC+ G + C D + ++C
Sbjct: 760 CVNGGTCVGSGASFSCICRDGWE---GRTCTHNTNDCNPLPCYNGGI-CVDGVNW-FRC- 813
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQK 134
+C GF G C+++ C G +C + G +C SCP G G +CQ V +
Sbjct: 814 ECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRC-SCPPGRAGP--RCQEVIGFGR 870
Query: 135 PCGRERRCMPKSTSPYYECEGC 156
C P +S +C C
Sbjct: 871 SCWSRGTPFPHGSSWVEDCNSC 892
Score = 43.2 bits (97), Expect = 0.004
Identities = 36/118 (30%), Positives = 48/118 (40%), Gaps = 9/118 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G CVD FRCE PG D + C ++PC G C D +G Y+C CP G
Sbjct: 801 GGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYG-ATCVDEING-YRC-SCPPG- 856
Query: 81 HGNGVECYRISCRANTCF-QGVSCEE-TQYGPKCGSCPTGYVGDGRQCQHVCDAQKPC 136
G C + +C+ +G + + C SC + R C V KPC
Sbjct: 857 -RAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRC--LDGRRDCSKVWCGWKPC 911
>AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein.
Length = 1238
Score = 77.8 bits (183), Expect = 1e-13
Identities = 59/176 (33%), Positives = 80/176 (45%), Gaps = 16/176 (9%)
Query: 15 PFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCG 74
P+ CV CV+ Q CE G D + S +PC G PD +Y+C
Sbjct: 278 PYPGCVHGSCVEPWQ-CNCETNWGGLLCD-KDLNYCGSHHPCTNGGTCINAEPD-QYRC- 333
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--A 132
CP G+ G E +C +N C G SC E G +C CP+G+ G C D A
Sbjct: 334 TCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFEC-HCPSGW--SGPTCALDIDECA 390
Query: 133 QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
PC C+ + +EC CP QW G TC +D +EC+ +PC + SC+N
Sbjct: 391 SNPCAAGGTCVDQVDG--FECI-CPE--QWVGATCQLDANECE-GKPCLNAFSCKN 440
Score = 56.4 bits (130), Expect = 4e-07
Identities = 46/151 (30%), Positives = 60/151 (39%), Gaps = 11/151 (7%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C + G+ C+ PG + + C GG C+DL +G YQC CP GF G
Sbjct: 438 CKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGT--CKDLVNG-YQC-VCPRGFGGR 493
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCM 143
E R C ++ C G CE+ G C CP G+ G + PC RC
Sbjct: 494 HCELERDKCASSPCHSGGLCEDLADGFHC-HCPQGFSGPLCEVDVDLCEPSPCRNGARCY 552
Query: 144 PKSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
YY C CP + G C V + C
Sbjct: 553 -NLEGDYY-C-ACPDDF--GGKNCSVPREPC 578
Score = 56.4 bits (130), Expect = 4e-07
Identities = 48/164 (29%), Positives = 69/164 (42%), Gaps = 18/164 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C+D FRC CP +G+ C T C +PC R C DL + Y C C
Sbjct: 648 GGTCIDEVDAFRCF-CPSGW--EGELCDTNPNDCLPDPCHS-RGRCYDLVNDFY-CA-CD 701
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDG-RQCQHVCDAQKPC 136
G+ G C A TC G +C ++ +C +CP G+ G ++ PC
Sbjct: 702 DGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRC-ACPPGWKGSTCAVAKNSSCLPNPC 760
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPC 179
C+ S + C C G W G TC + ++C+ + PC
Sbjct: 761 VNGGTCVGSGAS--FSCI-CRDG--WEGRTCTHNTNDCNPL-PC 798
Score = 54.4 bits (125), Expect = 2e-06
Identities = 41/142 (28%), Positives = 61/142 (42%), Gaps = 13/142 (9%)
Query: 19 CV-GERCVDTDQGFRCERCPGSQTSDGQTCR---TACSANPCFGGRVPCQDLPDGRYQCG 74
CV G CV + F C G + G+TC C+ PC+ G + C D + ++C
Sbjct: 760 CVNGGTCVGSGASFSCICRDGWE---GRTCTHNTNDCNPLPCYNGGI-CVDGVNW-FRC- 813
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQK 134
+C GF G C+++ C G +C + G +C SCP G G +CQ V +
Sbjct: 814 ECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRC-SCPPGRAGP--RCQEVIGFGR 870
Query: 135 PCGRERRCMPKSTSPYYECEGC 156
C P +S +C C
Sbjct: 871 SCWSRGTPFPHGSSWVEDCNSC 892
Score = 53.2 bits (122), Expect = 4e-06
Identities = 49/164 (29%), Positives = 66/164 (40%), Gaps = 20/164 (12%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRT---ACSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C + GF C CP + G TC C++NPC G C D DG ++C CP
Sbjct: 359 GGSCHEVPSGFECH-CPSGWS--GPTCALDIDECASNPCAAGGT-CVDQVDG-FEC-ICP 412
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQKPC 136
+ G + C C SC+ G C C G+ G C +V D + C
Sbjct: 413 EQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYC-DCIPGW--KGINCHINVNDCRGQC 469
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPC 179
C K Y+C CP G+ G C ++ D+C PC
Sbjct: 470 QHGGTC--KDLVNGYQCV-CPRGF--GGRHCELERDKC-ASSPC 507
Score = 43.2 bits (97), Expect = 0.004
Identities = 36/118 (30%), Positives = 48/118 (40%), Gaps = 9/118 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G CVD FRCE PG D + C ++PC G C D +G Y+C CP G
Sbjct: 801 GGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYG-ATCVDEING-YRC-SCPPG- 856
Query: 81 HGNGVECYRISCRANTCF-QGVSCEE-TQYGPKCGSCPTGYVGDGRQCQHVCDAQKPC 136
G C + +C+ +G + + C SC + R C V KPC
Sbjct: 857 -RAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRC--LDGRRDCSKVWCGWKPC 911
>AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein.
Length = 1238
Score = 77.8 bits (183), Expect = 1e-13
Identities = 59/176 (33%), Positives = 80/176 (45%), Gaps = 16/176 (9%)
Query: 15 PFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCG 74
P+ CV CV+ Q CE G D + S +PC G PD +Y+C
Sbjct: 278 PYPGCVHGSCVEPWQ-CNCETNWGGLLCD-KDLNYCGSHHPCTNGGTCINAEPD-QYRC- 333
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--A 132
CP G+ G E +C +N C G SC E G +C CP+G+ G C D A
Sbjct: 334 TCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFEC-HCPSGW--SGPTCALDIDECA 390
Query: 133 QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
PC C+ + +EC CP QW G TC +D +EC+ +PC + SC+N
Sbjct: 391 SNPCAAGGTCVDQVDG--FECI-CPE--QWVGATCQLDANECE-GKPCLNAFSCKN 440
Score = 56.4 bits (130), Expect = 4e-07
Identities = 46/151 (30%), Positives = 60/151 (39%), Gaps = 11/151 (7%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C + G+ C+ PG + + C GG C+DL +G YQC CP GF G
Sbjct: 438 CKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGT--CKDLVNG-YQC-VCPRGFGGR 493
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCM 143
E R C ++ C G CE+ G C CP G+ G + PC RC
Sbjct: 494 HCELERDKCASSPCHSGGLCEDLADGFHC-HCPQGFSGPLCEVDVDLCEPSPCRNGARCY 552
Query: 144 PKSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
YY C CP + G C V + C
Sbjct: 553 -NLEGDYY-C-ACPDDF--GGKNCSVPREPC 578
Score = 56.4 bits (130), Expect = 4e-07
Identities = 48/164 (29%), Positives = 69/164 (42%), Gaps = 18/164 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C+D FRC CP +G+ C T C +PC R C DL + Y C C
Sbjct: 648 GGTCIDEVDAFRCF-CPSGW--EGELCDTNPNDCLPDPCHS-RGRCYDLVNDFY-CA-CD 701
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDG-RQCQHVCDAQKPC 136
G+ G C A TC G +C ++ +C +CP G+ G ++ PC
Sbjct: 702 DGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRC-ACPPGWKGSTCAVAKNSSCLPNPC 760
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPC 179
C+ S + C C G W G TC + ++C+ + PC
Sbjct: 761 VNGGTCVGSGAS--FSCI-CRDG--WEGRTCTHNTNDCNPL-PC 798
Score = 54.4 bits (125), Expect = 2e-06
Identities = 41/142 (28%), Positives = 61/142 (42%), Gaps = 13/142 (9%)
Query: 19 CV-GERCVDTDQGFRCERCPGSQTSDGQTCR---TACSANPCFGGRVPCQDLPDGRYQCG 74
CV G CV + F C G + G+TC C+ PC+ G + C D + ++C
Sbjct: 760 CVNGGTCVGSGASFSCICRDGWE---GRTCTHNTNDCNPLPCYNGGI-CVDGVNW-FRC- 813
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQK 134
+C GF G C+++ C G +C + G +C SCP G G +CQ V +
Sbjct: 814 ECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRC-SCPPGRAGP--RCQEVIGFGR 870
Query: 135 PCGRERRCMPKSTSPYYECEGC 156
C P +S +C C
Sbjct: 871 SCWSRGTPFPHGSSWVEDCNSC 892
Score = 53.2 bits (122), Expect = 4e-06
Identities = 49/164 (29%), Positives = 66/164 (40%), Gaps = 20/164 (12%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRT---ACSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C + GF C CP + G TC C++NPC G C D DG ++C CP
Sbjct: 359 GGSCHEVPSGFECH-CPSGWS--GPTCALDIDECASNPCAAGGT-CVDQVDG-FEC-ICP 412
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQKPC 136
+ G + C C SC+ G C C G+ G C +V D + C
Sbjct: 413 EQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYC-DCIPGW--KGINCHINVNDCRGQC 469
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPC 179
C K Y+C CP G+ G C ++ D+C PC
Sbjct: 470 QHGGTC--KDLVNGYQCV-CPRGF--GGRHCELERDKC-ASSPC 507
Score = 43.2 bits (97), Expect = 0.004
Identities = 36/118 (30%), Positives = 48/118 (40%), Gaps = 9/118 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G CVD FRCE PG D + C ++PC G C D +G Y+C CP G
Sbjct: 801 GGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYG-ATCVDEING-YRC-SCPPG- 856
Query: 81 HGNGVECYRISCRANTCF-QGVSCEE-TQYGPKCGSCPTGYVGDGRQCQHVCDAQKPC 136
G C + +C+ +G + + C SC + R C V KPC
Sbjct: 857 -RAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRC--LDGRRDCSKVWCGWKPC 911
>AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein.
Length = 1238
Score = 77.4 bits (182), Expect = 2e-13
Identities = 58/176 (32%), Positives = 81/176 (46%), Gaps = 16/176 (9%)
Query: 15 PFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCG 74
P+ CV CV+ Q CE G D + S +PC G PD +Y+C
Sbjct: 278 PYPGCVHGSCVEPWQ-CNCETNWGGLLCD-KDLNYCGSHHPCTNGGTCINAEPD-QYRC- 333
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--A 132
CP G+ G E +C +N C G SC E G +C CP+G+ G C D A
Sbjct: 334 TCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFEC-HCPSGW--SGPTCALDIDECA 390
Query: 133 QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
PC C+ + +EC CP QW G TC +D+++C+ +PC + SC+N
Sbjct: 391 SNPCAAGGTCVDQVDG--FECI-CPE--QWVGATCQLDVNDCE-GKPCLNAFSCKN 440
Score = 56.4 bits (130), Expect = 4e-07
Identities = 46/151 (30%), Positives = 60/151 (39%), Gaps = 11/151 (7%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C + G+ C+ PG + + C GG C+DL +G YQC CP GF G
Sbjct: 438 CKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGT--CKDLVNG-YQC-VCPRGFGGR 493
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCM 143
E R C ++ C G CE+ G C CP G+ G + PC RC
Sbjct: 494 HCELERDKCASSPCHSGGLCEDLADGFHC-HCPQGFSGPLCEVDVDLCEPSPCRNGARCY 552
Query: 144 PKSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
YY C CP + G C V + C
Sbjct: 553 -NLEGDYY-C-ACPDDF--GGKNCSVPREPC 578
Score = 56.4 bits (130), Expect = 4e-07
Identities = 48/164 (29%), Positives = 69/164 (42%), Gaps = 18/164 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C+D FRC CP +G+ C T C +PC R C DL + Y C C
Sbjct: 648 GGTCIDEVDAFRCF-CPSGW--EGELCDTNPNDCLPDPCHS-RGRCYDLVNDFY-CA-CD 701
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDG-RQCQHVCDAQKPC 136
G+ G C A TC G +C ++ +C +CP G+ G ++ PC
Sbjct: 702 DGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRC-ACPPGWKGSTCAVAKNSSCLPNPC 760
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPC 179
C+ S + C C G W G TC + ++C+ + PC
Sbjct: 761 VNGGTCVGSGAS--FSCI-CRDG--WEGRTCTHNTNDCNPL-PC 798
Score = 54.4 bits (125), Expect = 2e-06
Identities = 41/142 (28%), Positives = 61/142 (42%), Gaps = 13/142 (9%)
Query: 19 CV-GERCVDTDQGFRCERCPGSQTSDGQTCR---TACSANPCFGGRVPCQDLPDGRYQCG 74
CV G CV + F C G + G+TC C+ PC+ G + C D + ++C
Sbjct: 760 CVNGGTCVGSGASFSCICRDGWE---GRTCTHNTNDCNPLPCYNGGI-CVDGVNW-FRC- 813
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQK 134
+C GF G C+++ C G +C + G +C SCP G G +CQ V +
Sbjct: 814 ECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRC-SCPPGRAGP--RCQEVIGFGR 870
Query: 135 PCGRERRCMPKSTSPYYECEGC 156
C P +S +C C
Sbjct: 871 SCWSRGTPFPHGSSWVEDCNSC 892
Score = 52.4 bits (120), Expect = 6e-06
Identities = 49/164 (29%), Positives = 66/164 (40%), Gaps = 20/164 (12%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRT---ACSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C + GF C CP + G TC C++NPC G C D DG ++C CP
Sbjct: 359 GGSCHEVPSGFECH-CPSGWS--GPTCALDIDECASNPCAAGGT-CVDQVDG-FEC-ICP 412
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQKPC 136
+ G + C C SC+ G C C G+ G C +V D + C
Sbjct: 413 EQWVGATCQLDVNDCEGKPCLNAFSCKNLIGGYYC-DCIPGW--KGINCHINVNDCRGQC 469
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPC 179
C K Y+C CP G+ G C ++ D+C PC
Sbjct: 470 QHGGTC--KDLVNGYQCV-CPRGF--GGRHCELERDKC-ASSPC 507
Score = 43.2 bits (97), Expect = 0.004
Identities = 36/118 (30%), Positives = 48/118 (40%), Gaps = 9/118 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G CVD FRCE PG D + C ++PC G C D +G Y+C CP G
Sbjct: 801 GGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYG-ATCVDEING-YRC-SCPPG- 856
Query: 81 HGNGVECYRISCRANTCF-QGVSCEE-TQYGPKCGSCPTGYVGDGRQCQHVCDAQKPC 136
G C + +C+ +G + + C SC + R C V KPC
Sbjct: 857 -RAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRC--LDGRRDCSKVWCGWKPC 911
>AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming growth
factor-beta binding protein 4L protein.
Length = 1624
Score = 76.2 bits (179), Expect = 4e-13
Identities = 97/350 (27%), Positives = 130/350 (37%), Gaps = 50/350 (14%)
Query: 2 HAGSMGDAGSMVTPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGR 60
H S D LC C + FRC CP G + S + C+ P G
Sbjct: 665 HGASCQDVDECTQSPGLCGRGACKNLPGSFRCV-CPAGFRGSACEEDVDECAQEPPPCGP 723
Query: 61 VPCQDLPDGRYQCGKCPSGFH--GNGVECYRISCRANT---CFQGVSCEETQYGPKCGSC 115
C D G + C CP+GF G G C + A + C G CE T+ +C C
Sbjct: 724 GRC-DNTAGSFHCA-CPAGFRSRGPGAPCQDVDECARSPPPCTYG-RCENTEGSFQC-VC 779
Query: 116 PTGYVGD--GRQCQHV--CDAQKPC-GRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDM 170
P G+ + G +C+ V C+ C G+E C+ S ++C CPSG+ + C D+
Sbjct: 780 PMGFQPNAAGSECEDVDECENHLACPGQE--CVNSPGS--FQCRACPSGHHLHRGRCTDV 835
Query: 171 DECDL-IRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGR 229
DEC PC C N E + G+R R C DV+EC +G
Sbjct: 836 DECSSGAPPCGPHGHCTNTE-------GSFRCSCAPGYRAPSG--RPGPCADVNECLEGD 886
Query: 230 ANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKR--CDPSY 287
P G C+NT GS+ C G+ C D D + C
Sbjct: 887 FCFPHGE-CLNT-----------DGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGI 934
Query: 288 CRRFNAVCGFGQKCVCNTGW-TGNGTVCGLDRDLDGHPDEQLPCNEPRCK 336
C N F +C+C G G LD D L C RC+
Sbjct: 935 CT--NTDGSF--ECICPPGHRAGPDLASCLDVDECRERGPAL-CGSQRCE 979
Score = 63.3 bits (147), Expect = 3e-09
Identities = 79/283 (27%), Positives = 114/283 (40%), Gaps = 52/283 (18%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSD-GQTCRTACSAN----PCFGGRVPCQDLPDGRYQC 73
C RC ++ FRC PG + C + PC GR C++ P G + C
Sbjct: 598 CAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGR--CENTP-GSFLC 654
Query: 74 GKCPSGFHG--NGVECYRI-SCRAN--TCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQH 128
CP+G+ +G C + C + C +G +C+ +C CP G+ G C+
Sbjct: 655 -VCPAGYQAAPHGASCQDVDECTQSPGLCGRG-ACKNLPGSFRC-VCPAGFRGSA--CEE 709
Query: 129 VCD--AQK--PCGRERRCMPKSTSPYYECEGCPSGYQWN--GYTCVDMDECDLIRPCDDL 182
D AQ+ PCG RC +T+ + C CP+G++ G C D+DEC P
Sbjct: 710 DVDECAQEPPPCG-PGRC--DNTAGSFHC-ACPAGFRSRGPGAPCQDVDECARSPPPCTY 765
Query: 183 VSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
C N E + G C DVDEC + A CP G+ CVN+P
Sbjct: 766 GRCENTEGSFQCVCPMGFQPNAAG----------SECEDVDECENHLA-CP-GQECVNSP 813
Query: 243 QYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDP 285
GS+ C C ++++ R C D D P
Sbjct: 814 -----------GSFQCRACPSGHHLHRGR-CTDVDECSSGAPP 844
Score = 54.8 bits (126), Expect = 1e-06
Identities = 59/203 (29%), Positives = 79/203 (38%), Gaps = 35/203 (17%)
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWN--GYTCVDMDECDLIRPCDDLVSCRNEEXXXX 193
CG RC+ + + Y C C SG++ + G C+D+DEC + P C N
Sbjct: 556 CG-PGRCISRPSG--YTC-ACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFR 611
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQ 253
G+R R C+DVDEC C GR C NTP
Sbjct: 612 CVC-------GPGFRAGP---RAAECLDVDECHRVPPPCDLGR-CENTP----------- 649
Query: 254 GSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCNTGWTGNGT 312
GS++CV G+ C D D + P C R G +CVC G+ G+
Sbjct: 650 GSFLCVCPAGYQAAPHGASCQDVDECTQ--SPGLCGRGACKNLPGSFRCVCPAGF--RGS 705
Query: 313 VCGLDRDLDGHPDEQLPCNEPRC 335
C + D+D E PC RC
Sbjct: 706 AC--EEDVDECAQEPPPCGPGRC 726
Score = 54.0 bits (124), Expect = 2e-06
Identities = 75/270 (27%), Positives = 102/270 (37%), Gaps = 45/270 (16%)
Query: 24 CVDTDQGFRCERCPGSQTSD-GQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C++TD F C PG + G +C CS + C + DG ++C CP G
Sbjct: 894 CLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGI-CTNT-DGSFEC-ICPPGH 950
Query: 81 HGNG--VECYRIS-CRAN--TCFQGVSCEETQYGPKC-GSCPTGY-VGDGRQCQHVCDAQ 133
C + CR CE + +C C GY G C V + Q
Sbjct: 951 RAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQ 1010
Query: 134 K--P--CGRERRCMPKSTSPYYECE-GCPSGYQWN-GYTCVDMDECDLIRPCDDLVSCRN 187
+ P CG +R C ++T Y C C GYQ G C D+DEC C C+N
Sbjct: 1011 EYGPEICGAQR-C--ENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQN 1067
Query: 188 EEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSN 247
QG+ G + R HCVDV+EC + C LC N
Sbjct: 1068 -------LPGSFQCLCDQGYEGARDGR---HCVDVNECETLQGVC-GAALCEN------- 1109
Query: 248 PVSSLQGSYICV-PCGGHYYVNTTRPCFDP 276
++GS++CV P + T C P
Sbjct: 1110 ----VEGSFLCVCPNSPEEFDPMTGRCVPP 1135
Score = 42.7 bits (96), Expect = 0.005
Identities = 32/107 (29%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
Query: 17 KLCVGERCVDTDQGFRC-ERC-PGSQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQ 72
++C +RC +T +RC C PG Q + G C+ C G CQ+LP G +Q
Sbjct: 1015 EICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLP-GSFQ 1073
Query: 73 CGKCPSGFHG--NGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCP 116
C C G+ G +G C ++ C G + E G CP
Sbjct: 1074 C-LCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCP 1119
Score = 41.1 bits (92), Expect = 0.015
Identities = 42/134 (31%), Positives = 55/134 (41%), Gaps = 16/134 (11%)
Query: 18 LCVGERCVDTDQGFRCER-C-PGSQTSDGQTCRTA--CSA-NPCFGGRVPCQDLPDGRYQ 72
LC +RC ++ +RC R C PG TC C P G C++ P G Y+
Sbjct: 972 LCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTP-GSYR 1030
Query: 73 C-GKCPSGFHGN-GVECYRI-SCRANT-CFQGVSCEETQYGPKCGSCPTGYVG--DGRQC 126
C C G+ G C + CR + C C+ +C C GY G DGR C
Sbjct: 1031 CTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQC-LCDQGYEGARDGRHC 1089
Query: 127 QHV--CDA-QKPCG 137
V C+ Q CG
Sbjct: 1090 VDVNECETLQGVCG 1103
Score = 33.5 bits (73), Expect = 3.0
Identities = 15/27 (55%), Positives = 17/27 (62%), Gaps = 1/27 (3%)
Query: 215 RREHCVDVDECADGRANCPRGRLCVNT 241
+R C+D DECAD C GR CVNT
Sbjct: 1290 QRLECIDNDECADEEPACEGGR-CVNT 1315
Score = 32.3 bits (70), Expect = 7.0
Identities = 17/32 (53%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Query: 210 TGNERRREHCVDVDECADGRANCPRGRLCVNT 241
TG ER C DVDECA G C G C NT
Sbjct: 346 TGFERVNGSCEDVDECATG-GRCQHGE-CANT 375
>AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming growth
factor-beta binding protein 4S protein.
Length = 1557
Score = 76.2 bits (179), Expect = 4e-13
Identities = 97/350 (27%), Positives = 130/350 (37%), Gaps = 50/350 (14%)
Query: 2 HAGSMGDAGSMVTPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGR 60
H S D LC C + FRC CP G + S + C+ P G
Sbjct: 598 HGASCQDVDECTQSPGLCGRGACKNLPGSFRCV-CPAGFRGSACEEDVDECAQEPPPCGP 656
Query: 61 VPCQDLPDGRYQCGKCPSGFH--GNGVECYRISCRANT---CFQGVSCEETQYGPKCGSC 115
C D G + C CP+GF G G C + A + C G CE T+ +C C
Sbjct: 657 GRC-DNTAGSFHCA-CPAGFRSRGPGAPCQDVDECARSPPPCTYG-RCENTEGSFQC-VC 712
Query: 116 PTGYVGD--GRQCQHV--CDAQKPC-GRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDM 170
P G+ + G +C+ V C+ C G+E C+ S ++C CPSG+ + C D+
Sbjct: 713 PMGFQPNAAGSECEDVDECENHLACPGQE--CVNSPGS--FQCRACPSGHHLHRGRCTDV 768
Query: 171 DECDL-IRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGR 229
DEC PC C N E + G+R R C DV+EC +G
Sbjct: 769 DECSSGAPPCGPHGHCTNTE-------GSFRCSCAPGYRAPSG--RPGPCADVNECLEGD 819
Query: 230 ANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKR--CDPSY 287
P G C+NT GS+ C G+ C D D + C
Sbjct: 820 FCFPHGE-CLNT-----------DGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGI 867
Query: 288 CRRFNAVCGFGQKCVCNTGW-TGNGTVCGLDRDLDGHPDEQLPCNEPRCK 336
C N F +C+C G G LD D L C RC+
Sbjct: 868 CT--NTDGSF--ECICPPGHRAGPDLASCLDVDECRERGPAL-CGSQRCE 912
Score = 63.3 bits (147), Expect = 3e-09
Identities = 79/283 (27%), Positives = 114/283 (40%), Gaps = 52/283 (18%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSD-GQTCRTACSAN----PCFGGRVPCQDLPDGRYQC 73
C RC ++ FRC PG + C + PC GR C++ P G + C
Sbjct: 531 CAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGR--CENTP-GSFLC 587
Query: 74 GKCPSGFHG--NGVECYRI-SCRAN--TCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQH 128
CP+G+ +G C + C + C +G +C+ +C CP G+ G C+
Sbjct: 588 -VCPAGYQAAPHGASCQDVDECTQSPGLCGRG-ACKNLPGSFRC-VCPAGFRGSA--CEE 642
Query: 129 VCD--AQK--PCGRERRCMPKSTSPYYECEGCPSGYQWN--GYTCVDMDECDLIRPCDDL 182
D AQ+ PCG RC +T+ + C CP+G++ G C D+DEC P
Sbjct: 643 DVDECAQEPPPCG-PGRC--DNTAGSFHC-ACPAGFRSRGPGAPCQDVDECARSPPPCTY 698
Query: 183 VSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
C N E + G C DVDEC + A CP G+ CVN+P
Sbjct: 699 GRCENTEGSFQCVCPMGFQPNAAG----------SECEDVDECENHLA-CP-GQECVNSP 746
Query: 243 QYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDP 285
GS+ C C ++++ R C D D P
Sbjct: 747 -----------GSFQCRACPSGHHLHRGR-CTDVDECSSGAPP 777
Score = 54.8 bits (126), Expect = 1e-06
Identities = 59/203 (29%), Positives = 79/203 (38%), Gaps = 35/203 (17%)
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWN--GYTCVDMDECDLIRPCDDLVSCRNEEXXXX 193
CG RC+ + + Y C C SG++ + G C+D+DEC + P C N
Sbjct: 489 CG-PGRCISRPSG--YTC-ACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFR 544
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQ 253
G+R R C+DVDEC C GR C NTP
Sbjct: 545 CVC-------GPGFRAGP---RAAECLDVDECHRVPPPCDLGR-CENTP----------- 582
Query: 254 GSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCNTGWTGNGT 312
GS++CV G+ C D D + P C R G +CVC G+ G+
Sbjct: 583 GSFLCVCPAGYQAAPHGASCQDVDECTQ--SPGLCGRGACKNLPGSFRCVCPAGF--RGS 638
Query: 313 VCGLDRDLDGHPDEQLPCNEPRC 335
C + D+D E PC RC
Sbjct: 639 AC--EEDVDECAQEPPPCGPGRC 659
Score = 54.0 bits (124), Expect = 2e-06
Identities = 75/270 (27%), Positives = 102/270 (37%), Gaps = 45/270 (16%)
Query: 24 CVDTDQGFRCERCPGSQTSD-GQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C++TD F C PG + G +C CS + C + DG ++C CP G
Sbjct: 827 CLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGI-CTNT-DGSFEC-ICPPGH 883
Query: 81 HGNG--VECYRIS-CRAN--TCFQGVSCEETQYGPKC-GSCPTGY-VGDGRQCQHVCDAQ 133
C + CR CE + +C C GY G C V + Q
Sbjct: 884 RAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQ 943
Query: 134 K--P--CGRERRCMPKSTSPYYECE-GCPSGYQWN-GYTCVDMDECDLIRPCDDLVSCRN 187
+ P CG +R C ++T Y C C GYQ G C D+DEC C C+N
Sbjct: 944 EYGPEICGAQR-C--ENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQN 1000
Query: 188 EEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSN 247
QG+ G + R HCVDV+EC + C LC N
Sbjct: 1001 -------LPGSFQCLCDQGYEGARDGR---HCVDVNECETLQGVC-GAALCEN------- 1042
Query: 248 PVSSLQGSYICV-PCGGHYYVNTTRPCFDP 276
++GS++CV P + T C P
Sbjct: 1043 ----VEGSFLCVCPNSPEEFDPMTGRCVPP 1068
Score = 42.7 bits (96), Expect = 0.005
Identities = 32/107 (29%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
Query: 17 KLCVGERCVDTDQGFRC-ERC-PGSQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQ 72
++C +RC +T +RC C PG Q + G C+ C G CQ+LP G +Q
Sbjct: 948 EICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLP-GSFQ 1006
Query: 73 CGKCPSGFHG--NGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCP 116
C C G+ G +G C ++ C G + E G CP
Sbjct: 1007 C-LCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCP 1052
Score = 41.1 bits (92), Expect = 0.015
Identities = 42/134 (31%), Positives = 55/134 (41%), Gaps = 16/134 (11%)
Query: 18 LCVGERCVDTDQGFRCER-C-PGSQTSDGQTCRTA--CSA-NPCFGGRVPCQDLPDGRYQ 72
LC +RC ++ +RC R C PG TC C P G C++ P G Y+
Sbjct: 905 LCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTP-GSYR 963
Query: 73 C-GKCPSGFHGN-GVECYRI-SCRANT-CFQGVSCEETQYGPKCGSCPTGYVG--DGRQC 126
C C G+ G C + CR + C C+ +C C GY G DGR C
Sbjct: 964 CTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQC-LCDQGYEGARDGRHC 1022
Query: 127 QHV--CDA-QKPCG 137
V C+ Q CG
Sbjct: 1023 VDVNECETLQGVCG 1036
Score = 33.5 bits (73), Expect = 3.0
Identities = 15/27 (55%), Positives = 17/27 (62%), Gaps = 1/27 (3%)
Query: 215 RREHCVDVDECADGRANCPRGRLCVNT 241
+R C+D DECAD C GR CVNT
Sbjct: 1223 QRLECIDNDECADEEPACEGGR-CVNT 1248
Score = 32.3 bits (70), Expect = 7.0
Identities = 17/32 (53%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Query: 210 TGNERRREHCVDVDECADGRANCPRGRLCVNT 241
TG ER C DVDECA G C G C NT
Sbjct: 279 TGFERVNGSCEDVDECATG-GRCQHGE-CANT 308
>Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding
protein-4 protein.
Length = 1587
Score = 74.9 bits (176), Expect = 1e-12
Identities = 97/350 (27%), Positives = 130/350 (37%), Gaps = 50/350 (14%)
Query: 2 HAGSMGDAGSMVTPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGR 60
H S D LC C + FRC CP G + S + C+ P G
Sbjct: 628 HGASCQDVDECTQSPGLCGRGGCKNLPGSFRCV-CPAGFRGSACEEDVDECAQEPPPCGP 686
Query: 61 VPCQDLPDGRYQCGKCPSGFH--GNGVECYRISCRANT---CFQGVSCEETQYGPKCGSC 115
C D G + C CP+GF G G C + A + C G CE T+ +C C
Sbjct: 687 GRC-DNTAGSFHCA-CPAGFRSRGPGAPCQDVDECARSPPPCTYG-RCENTEGSFQC-VC 742
Query: 116 PTGYVGD--GRQCQHV--CDAQKPC-GRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDM 170
P G+ + G +C+ V C+ C G+E C+ S ++C CPSG+ + C D+
Sbjct: 743 PMGFQPNTAGSECEDVDECENHLACPGQE--CVNSPGS--FQCRTCPSGHHLHRGRCTDV 798
Query: 171 DECDL-IRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGR 229
DEC PC C N E + G+R R C DV+EC +G
Sbjct: 799 DECSSGAPPCGPHGHCTNTE-------GSFRCSCAPGYRAPSG--RPGPCADVNECLEGD 849
Query: 230 ANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKR--CDPSY 287
P G C+NT GS+ C G+ C D D + C
Sbjct: 850 FCFPHGE-CLNT-----------DGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGI 897
Query: 288 CRRFNAVCGFGQKCVCNTGW-TGNGTVCGLDRDLDGHPDEQLPCNEPRCK 336
C N F +C+C G G LD D L C RC+
Sbjct: 898 CT--NTDGSF--ECICPPGHRAGPDLASCLDVDECRERGPAL-CGSQRCE 942
Score = 62.9 bits (146), Expect = 4e-09
Identities = 79/283 (27%), Positives = 113/283 (39%), Gaps = 52/283 (18%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSD-GQTCRTACSAN----PCFGGRVPCQDLPDGRYQC 73
C RC ++ FRC PG + C + PC GR C++ P G + C
Sbjct: 561 CAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGR--CENTP-GSFLC 617
Query: 74 GKCPSGFHG--NGVECYRI-SCRAN--TCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQH 128
CP+G+ +G C + C + C +G C+ +C CP G+ G C+
Sbjct: 618 -VCPAGYQAAPHGASCQDVDECTQSPGLCGRG-GCKNLPGSFRC-VCPAGFRGSA--CEE 672
Query: 129 VCD--AQK--PCGRERRCMPKSTSPYYECEGCPSGYQWN--GYTCVDMDECDLIRPCDDL 182
D AQ+ PCG RC +T+ + C CP+G++ G C D+DEC P
Sbjct: 673 DVDECAQEPPPCG-PGRC--DNTAGSFHC-ACPAGFRSRGPGAPCQDVDECARSPPPCTY 728
Query: 183 VSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
C N E + G C DVDEC + A CP G+ CVN+P
Sbjct: 729 GRCENTEGSFQCVCPMGFQPNTAG----------SECEDVDECENHLA-CP-GQECVNSP 776
Query: 243 QYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDP 285
GS+ C C ++++ R C D D P
Sbjct: 777 -----------GSFQCRTCPSGHHLHRGR-CTDVDECSSGAPP 807
Score = 55.6 bits (128), Expect = 7e-07
Identities = 59/203 (29%), Positives = 79/203 (38%), Gaps = 35/203 (17%)
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWN--GYTCVDMDECDLIRPCDDLVSCRNEEXXXX 193
CG RC+ + + Y C C SG++ + G C+D+DEC + P C N
Sbjct: 519 CG-PGRCISRPSG--YTC-ACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFR 574
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQ 253
G+R R C+DVDEC C GR C NTP
Sbjct: 575 CVC-------GPGFRAGP---RAAECLDVDECHRVPPPCDLGR-CENTP----------- 612
Query: 254 GSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCNTGWTGNGT 312
GS++CV G+ C D D + P C R G +CVC G+ G+
Sbjct: 613 GSFLCVCPAGYQAAPHGASCQDVDECTQ--SPGLCGRGGCKNLPGSFRCVCPAGF--RGS 668
Query: 313 VCGLDRDLDGHPDEQLPCNEPRC 335
C + D+D E PC RC
Sbjct: 669 AC--EEDVDECAQEPPPCGPGRC 689
Score = 54.4 bits (125), Expect = 2e-06
Identities = 76/274 (27%), Positives = 104/274 (37%), Gaps = 45/274 (16%)
Query: 24 CVDTDQGFRCERCPGSQTSD-GQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C++TD F C PG + G +C CS + C + DG ++C CP G
Sbjct: 857 CLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGI-CTNT-DGSFEC-ICPPGH 913
Query: 81 HGNG--VECYRIS-CRAN--TCFQGVSCEETQYGPKC-GSCPTGY-VGDGRQCQHVCDAQ 133
C + CR CE + +C C GY G C V + Q
Sbjct: 914 RAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQ 973
Query: 134 K--P--CGRERRCMPKSTSPYYECE-GCPSGYQWN-GYTCVDMDECDLIRPCDDLVSCRN 187
+ P CG +R C ++T Y C C GYQ G C D+DEC C C+N
Sbjct: 974 EYGPEICGAQR-C--ENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQN 1030
Query: 188 EEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSN 247
QG+ G + R HCVDV+EC + C LC N
Sbjct: 1031 -------LPGSFQCLCDQGYEGARDGR---HCVDVNECETLQGVC-GAALCEN------- 1072
Query: 248 PVSSLQGSYICV-PCGGHYYVNTTRPCFDPDSLV 280
++GS++CV P + T C P + V
Sbjct: 1073 ----VEGSFLCVCPNSPEEFDPMTGRCVPPRTSV 1102
Score = 42.7 bits (96), Expect = 0.005
Identities = 32/107 (29%), Positives = 46/107 (42%), Gaps = 9/107 (8%)
Query: 17 KLCVGERCVDTDQGFRC-ERC-PGSQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQ 72
++C +RC +T +RC C PG Q + G C+ C G CQ+LP G +Q
Sbjct: 978 EICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLP-GSFQ 1036
Query: 73 CGKCPSGFHG--NGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCP 116
C C G+ G +G C ++ C G + E G CP
Sbjct: 1037 C-LCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCP 1082
Score = 41.1 bits (92), Expect = 0.015
Identities = 42/134 (31%), Positives = 55/134 (41%), Gaps = 16/134 (11%)
Query: 18 LCVGERCVDTDQGFRCER-C-PGSQTSDGQTCRTA--CSA-NPCFGGRVPCQDLPDGRYQ 72
LC +RC ++ +RC R C PG TC C P G C++ P G Y+
Sbjct: 935 LCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTP-GSYR 993
Query: 73 C-GKCPSGFHGN-GVECYRI-SCRANT-CFQGVSCEETQYGPKCGSCPTGYVG--DGRQC 126
C C G+ G C + CR + C C+ +C C GY G DGR C
Sbjct: 994 CTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQC-LCDQGYEGARDGRHC 1052
Query: 127 QHV--CDA-QKPCG 137
V C+ Q CG
Sbjct: 1053 VDVNECETLQGVCG 1066
Score = 33.5 bits (73), Expect = 3.0
Identities = 15/27 (55%), Positives = 17/27 (62%), Gaps = 1/27 (3%)
Query: 215 RREHCVDVDECADGRANCPRGRLCVNT 241
+R C+D DECAD C GR CVNT
Sbjct: 1253 QRLECIDNDECADEEPACEGGR-CVNT 1278
Score = 32.3 bits (70), Expect = 7.0
Identities = 17/32 (53%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Query: 210 TGNERRREHCVDVDECADGRANCPRGRLCVNT 241
TG ER C DVDECA G C G C NT
Sbjct: 309 TGFERVNGSCEDVDECATG-GRCQHGE-CANT 338
>M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein.
Length = 2444
Score = 74.9 bits (176), Expect = 1e-12
Identities = 50/170 (29%), Positives = 72/170 (42%), Gaps = 8/170 (4%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
CV C D+ G++C+ PG ++ C +NPC G C+D+ G C C
Sbjct: 725 CVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGT-CKDMTSG-IVC-TCRE 781
Query: 79 GFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGR 138
GF G + C +N C +C + G KC +C Y G + A PC
Sbjct: 782 GFSGPNCQTNINECASNPCLNKGTCIDDVAGYKC-NCLLPYTGATCEVVLAPCAPSPCRN 840
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C + C CP+ G TC VD++EC ++ PC SC+N
Sbjct: 841 GGECRQSEDYESFSCV-CPTAGA-KGQTCEVDINEC-VLSPCRHGASCQN 887
Score = 63.7 bits (148), Expect = 2e-09
Identities = 93/329 (28%), Positives = 123/329 (37%), Gaps = 45/329 (13%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D C+ PG + + + C+++PC G C D D Y C CP+GF
Sbjct: 920 GGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNG-ANCTDCVDS-YTC-TCPAGF 976
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV---CDAQKPCG 137
G E C ++CF G +C + C CP G+ G CQHV CD+ +PC
Sbjct: 977 SGIHCENNTPDCTESSCFNGGTCVDGINSFTC-LCPPGFTGS--YCQHVVNECDS-RPCL 1032
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX 197
C + + C CP GY G C +L+ CD C+N
Sbjct: 1033 LGGTC--QDGRGLHRCT-CPQGY--TGPNCQ-----NLVHWCDS-SPCKNGGKCWQTHTQ 1081
Query: 198 XXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYI 257
S GW G + C E A R RLC Q+ V + G+
Sbjct: 1082 YRCECPS-GWTGLYCDVPSVSC----EVAAQRQGVDVARLC----QHGGLCVDA--GNTH 1130
Query: 258 CVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCG---FGQKCVCNTGWTGNGTVC 314
C Y T C D LV C PS C+ A C G C C G+ G
Sbjct: 1131 HCRCQAGY---TGSYCED---LVDECSPSPCQN-GATCTDYLGGYSCKCVAGYHGVNCSE 1183
Query: 315 GLDRDLDGHPDEQ-LPCNE-PRCKKDNCP 341
+D L HP + C + P K +CP
Sbjct: 1184 EIDECL-SHPCQNGGTCLDLPNTYKCSCP 1211
Score = 63.3 bits (147), Expect = 3e-09
Identities = 46/155 (29%), Positives = 60/155 (38%), Gaps = 12/155 (7%)
Query: 22 ERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPS 78
+ CV F CE C T G+ C + C PC G R KCP+
Sbjct: 1283 QNCVQRVNDFHCE-CRAGHT--GRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPA 1339
Query: 79 GFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQ--CQHVCDAQKPC 136
GF G E +C + C G +C P C C + G Q C PC
Sbjct: 1340 GFEGATCENDARTCGSLRCLNGGTCISGPRSPTC-LCLGPFTGPECQFPASSPCLGGNPC 1398
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMD 171
+ C P S SP+Y C CP+ ++NG C +D
Sbjct: 1399 YNQGTCEPTSESPFYRCL-CPA--KFNGLLCHILD 1430
Score = 57.6 bits (133), Expect = 2e-07
Identities = 46/168 (27%), Positives = 69/168 (41%), Gaps = 12/168 (7%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
C C+D G+ C PG S + C+ NPC G C+D +G + C +CP
Sbjct: 650 CDSGTCLDKIDGYECACEPGYTGSMCNSNIDECAGNPCHNGGT-CEDGING-FTC-RCPE 706
Query: 79 GFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGR 138
G+H C +N C G +C ++ G KC C G+ G + PC
Sbjct: 707 GYHDPTCLSEVNECNSNPCVHG-ACRDSLNGYKC-DCDPGWSGTNCDINNNECESNPCVN 764
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSC 185
C K + C C G+ +G C +++EC PC + +C
Sbjct: 765 GGTC--KDMTSGIVCT-CREGF--SGPNCQTNINEC-ASNPCLNKGTC 806
Score = 57.2 bits (132), Expect = 2e-07
Identities = 47/166 (28%), Positives = 73/166 (43%), Gaps = 15/166 (9%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C D D + C G+ + + C+++PC G C D DG Y+C C G+ G+
Sbjct: 618 CQDPDNAYLCFCLKGTTGPNCEINLDDCASSPCDSG--TCLDKIDG-YECA-CEPGYTGS 673
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA-QKPCGRERRC 142
C N C G +CE+ G C CP GY D V + PC C
Sbjct: 674 MCNSNIDECAGNPCHNGGTCEDGINGFTC-RCPEGY-HDPTCLSEVNECNSNPC-VHGAC 730
Query: 143 MPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
+ + Y+C+ C G W+G C ++ +EC+ PC + +C++
Sbjct: 731 --RDSLNGYKCD-CDPG--WSGTNCDINNNECE-SNPCVNGGTCKD 770
Score = 56.8 bits (131), Expect = 3e-07
Identities = 53/174 (30%), Positives = 63/174 (36%), Gaps = 18/174 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRT---ACSANP--CFGGRVPCQDLPDGRYQCGK 75
G CVD + C CP T GQ C C P C G C + G Y C
Sbjct: 269 GGACVDGVNTYNCP-CPPEWT--GQYCTEDVDECQLMPNACQNGGT-CHNTHGG-YNC-V 322
Query: 76 CPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
C +G+ G C + CF G +C + C CP G G C P
Sbjct: 323 CVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYC-ECPHGRTGLLCHLNDAC-ISNP 380
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDL-IRPCDDLVSCRN 187
C C + C CPSGY G C D+DEC L PC+ C N
Sbjct: 381 CNEGSNCDTNPVNGKAICT-CPSGY--TGPACSQDVDECSLGANPCEHAGKCIN 431
Score = 50.4 bits (115), Expect = 2e-05
Identities = 84/332 (25%), Positives = 124/332 (37%), Gaps = 48/332 (14%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCF-GGRVPCQDLPDGRYQCGKCPSGFHG 82
C+D F+C PG + + C+++PC GR C D + +QC +CP+GF G
Sbjct: 467 CLDQIGEFQCMCMPGYEGVHCEVNTDECASSPCLHNGR--CLDKIN-EFQC-ECPTGFTG 522
Query: 83 NGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQKPCGRERR 141
+ + C + C G C + C C GY G + CD PC
Sbjct: 523 HLCQYDVDECASTPCKNGAKCLDGPNTYTC-VCTEGYTGTHCEVDIDECDPD-PC-HYGS 579
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C K + C C GY G+ C +++EC +PC +C++ +
Sbjct: 580 C--KDGVATFTCL-CRPGY--TGHHCETNINECS-SQPCRLRGTCQDPDNAYLCFCL--- 630
Query: 201 XXXSQGWRGTGNERRREHCVDVDECADGRA-NCPRGRLCVNTPQYPSNPVSSLQGSYICV 259
+G G E + C C G + G C P Y + +S
Sbjct: 631 ----KGTTGPNCEINLDDCAS-SPCDSGTCLDKIDGYECACEPGYTGSMCNSNIDECAGN 685
Query: 260 PC--GG-------HYYVNTTRPCFDPDSL--VKRCDPSYCRRFNAVCG---FGQKCVCNT 305
PC GG + DP L V C+ + C + C G KC C+
Sbjct: 686 PCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPC--VHGACRDSLNGYKCDCDP 743
Query: 306 GWTGNGTVCGLDRDLDGHPDEQLPC-NEPRCK 336
GW +GT C D++ + E PC N CK
Sbjct: 744 GW--SGTNC----DINNNECESNPCVNGGTCK 769
Score = 50.4 bits (115), Expect = 2e-05
Identities = 43/137 (31%), Positives = 57/137 (41%), Gaps = 16/137 (11%)
Query: 29 QGFRCERCPGSQTSDGQTCRT---ACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGV 85
+ F C CP + + GQTC C +PC G CQ+ G Y+C C +G+ G
Sbjct: 851 ESFSCV-CP-TAGAKGQTCEVDINECVLSPCRHG-ASCQNT-HGXYRC-HCQAGYSGRNC 905
Query: 86 ECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCM 143
E CR N C G SC + C C G+ G C+ + A PC C
Sbjct: 906 ETDIDDCRPNPCHNGGSCTDGINTAFC-DCLPGF--RGTFCEEDINECASDPCRNGANCT 962
Query: 144 PKSTSPYYECEGCPSGY 160
S Y C CP+G+
Sbjct: 963 DCVDS--YTCT-CPAGF 976
Score = 50.0 bits (114), Expect = 3e-05
Identities = 54/181 (29%), Positives = 76/181 (41%), Gaps = 29/181 (16%)
Query: 20 VGERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKC 76
+G C D RC CP T G C+ C ++PC G Q +Y+C +C
Sbjct: 1033 LGGTCQDGRGLHRCT-CPQGYT--GPNCQNLVHWCDSSPCKNGGKCWQT--HTQYRC-EC 1086
Query: 77 PSGFHGNGVECYRISCRANTCFQGVSCEE-TQYGPKC---GS-----CPTGYVGDGRQCQ 127
PSG+ G + +SC QGV Q+G C G+ C GY G C+
Sbjct: 1087 PSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGS--YCE 1144
Query: 128 HVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVS 184
+ D + PC C Y C+ C +GY +G C ++DEC L PC + +
Sbjct: 1145 DLVDECSPSPCQNGATCTDYLGG--YSCK-CVAGY--HGVNCSEEIDEC-LSHPCQNGGT 1198
Query: 185 C 185
C
Sbjct: 1199 C 1199
Score = 49.2 bits (112), Expect = 6e-05
Identities = 48/169 (28%), Positives = 68/169 (40%), Gaps = 20/169 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPS-G 79
C+D G++C C T G TC C+ +PC G C+ D CP+ G
Sbjct: 806 CIDDVAGYKCN-CLLPYT--GATCEVVLAPCAPSPCRNGG-ECRQSEDYESFSCVCPTAG 861
Query: 80 FHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCG 137
G E C + C G SC+ T +C C GY GR C+ D PC
Sbjct: 862 AKGQTCEVDINECVLSPCRHGASCQNTHGXYRC-HCQAGY--SGRNCETDIDDCRPNPCH 918
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSC 185
C + + C+ C G++ G C D++EC PC + +C
Sbjct: 919 NGGSCTDGINTAF--CD-CLPGFR--GTFCEEDINEC-ASDPCRNGANC 961
Score = 46.8 bits (106), Expect = 3e-04
Identities = 49/161 (30%), Positives = 64/161 (39%), Gaps = 33/161 (20%)
Query: 31 FRCERCPGSQTSDGQTCRTA--CSANPCFGGRVPCQDLP-DGRYQCGKCPSGFHG----- 82
++C RCP + G++C+ A C++NPC G Q LP + Y C CP FHG
Sbjct: 125 YKC-RCPPGWS--GKSCQQADPCASNPCANGG---QCLPFEASYIC-HCPPSFHGPTCRQ 177
Query: 83 NGVEC---YRISCRANTCFQGVS-----CEETQYGPKCG----SCPTGYVGDGRQCQHVC 130
+ EC R+ TC V C T GP C C +G C+
Sbjct: 178 DVNECGQKPRLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTG 237
Query: 131 DAQKPCGRERRCMPKSTSPYYE--CEGCPSGYQWNGYTCVD 169
D C C+P T E + CP NG CVD
Sbjct: 238 DVTHECA----CLPGFTGQNCEENIDDCPGNNCKNGGACVD 274
Score = 45.6 bits (103), Expect = 7e-04
Identities = 43/148 (29%), Positives = 58/148 (39%), Gaps = 20/148 (13%)
Query: 35 RCPGSQTSDGQTCR---TACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS 91
RC T G C CS +PC G C+ D ++C C GF G E
Sbjct: 203 RCVCRATHTGPNCERPYVPCSPSPCQNGGT-CRPTGDVTHECA-CLPGFTGQNCEENIDD 260
Query: 92 CRANTCFQGVSCEETQYGPKCGSCPTGYVG-----DGRQCQHVCDAQKPCGRERRCMPKS 146
C N C G +C + C CP + G D +CQ + +A C C +
Sbjct: 261 CPGNNCKNGGACVDGVNTYNC-PCPPEWTGQYCTEDVDECQLMPNA---CQNGGTC--HN 314
Query: 147 TSPYYECEGCPSGYQWNGYTCVD-MDEC 173
T Y C C +G W G C + +D+C
Sbjct: 315 THGGYNCV-CVNG--WTGEDCSENIDDC 339
Score = 43.2 bits (97), Expect = 0.004
Identities = 51/172 (29%), Positives = 74/172 (43%), Gaps = 25/172 (14%)
Query: 21 GERCVDTDQGFRCERCP-GSQTSDGQTCRTAC-------SANP-CFGGRVPCQDLPDGRY 71
G C+D ++C CP G+Q + C S +P CF C D G Y
Sbjct: 1196 GGTCLDLPNTYKCS-CPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGT-CVDQVGG-Y 1252
Query: 72 QCGKCPSGFHGNGVECYRISCRANTC-FQGV-SCEETQYGPKCGSCPTGYVGDGRQCQHV 129
C CP GF G E C +N C +G +C + C C G+ GR+C+ V
Sbjct: 1253 SC-TCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHC-ECRAGHT--GRRCESV 1308
Query: 130 CDA--QKPCGRERRC-MPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIR 177
+ KPC C + +T+ + C+ CP+G++ G TC D C +R
Sbjct: 1309 INGCKGKPCKNGGTCAVASNTARGFICK-CPAGFE--GATCENDARTCGSLR 1357
Score = 41.1 bits (92), Expect = 0.015
Identities = 42/168 (25%), Positives = 63/168 (37%), Gaps = 13/168 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G +C+D + C G + + C +PC G C+D + C C G+
Sbjct: 540 GAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG--SCKD-GVATFTC-LCRPGY 595
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
G+ E C + C +C++ C C G G + A PC
Sbjct: 596 TGHHCETNINECSSQPCRLRGTCQDPDNAYLC-FCLKGTTGPNCEINLDDCASSPCD-SG 653
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C+ K YEC C GY G C ++DEC PC + +C +
Sbjct: 654 TCLDKIDG--YEC-ACEPGY--TGSMCNSNIDEC-AGNPCHNGGTCED 695
>AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein.
Length = 2556
Score = 74.9 bits (176), Expect = 1e-12
Identities = 50/170 (29%), Positives = 72/170 (42%), Gaps = 8/170 (4%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
CV C D+ G++C+ PG ++ C +NPC G C+D+ G C C
Sbjct: 725 CVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGT-CKDMTSG-IVC-TCRE 781
Query: 79 GFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGR 138
GF G + C +N C +C + G KC +C Y G + A PC
Sbjct: 782 GFSGPNCQTNINECASNPCLNKGTCIDDVAGYKC-NCLLPYTGATCEVVLAPCAPSPCRN 840
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C + C CP+ G TC VD++EC ++ PC SC+N
Sbjct: 841 GGECRQSEDYESFSCV-CPTAGA-KGQTCEVDINEC-VLSPCRHGASCQN 887
Score = 63.7 bits (148), Expect = 2e-09
Identities = 93/329 (28%), Positives = 123/329 (37%), Gaps = 45/329 (13%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D C+ PG + + + C+++PC G C D D Y C CP+GF
Sbjct: 920 GGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNG-ANCTDCVDS-YTC-TCPAGF 976
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV---CDAQKPCG 137
G E C ++CF G +C + C CP G+ G CQHV CD+ +PC
Sbjct: 977 SGIHCENNTPDCTESSCFNGGTCVDGINSFTC-LCPPGFTGS--YCQHVVNECDS-RPCL 1032
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX 197
C + + C CP GY G C +L+ CD C+N
Sbjct: 1033 LGGTC--QDGRGLHRCT-CPQGY--TGPNCQ-----NLVHWCDS-SPCKNGGKCWQTHTQ 1081
Query: 198 XXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYI 257
S GW G + C E A R RLC Q+ V + G+
Sbjct: 1082 YRCECPS-GWTGLYCDVPSVSC----EVAAQRQGVDVARLC----QHGGLCVDA--GNTH 1130
Query: 258 CVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCG---FGQKCVCNTGWTGNGTVC 314
C Y T C D LV C PS C+ A C G C C G+ G
Sbjct: 1131 HCRCQAGY---TGSYCED---LVDECSPSPCQN-GATCTDYLGGYSCKCVAGYHGVNCSE 1183
Query: 315 GLDRDLDGHPDEQ-LPCNE-PRCKKDNCP 341
+D L HP + C + P K +CP
Sbjct: 1184 EIDECL-SHPCQNGGTCLDLPNTYKCSCP 1211
Score = 63.3 bits (147), Expect = 3e-09
Identities = 46/155 (29%), Positives = 60/155 (38%), Gaps = 12/155 (7%)
Query: 22 ERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPS 78
+ CV F CE C T G+ C + C PC G R KCP+
Sbjct: 1283 QNCVQRVNDFHCE-CRAGHT--GRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPA 1339
Query: 79 GFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQ--CQHVCDAQKPC 136
GF G E +C + C G +C P C C + G Q C PC
Sbjct: 1340 GFEGATCENDARTCGSLRCLNGGTCISGPRSPTC-LCLGPFTGPECQFPASSPCLGGNPC 1398
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMD 171
+ C P S SP+Y C CP+ ++NG C +D
Sbjct: 1399 YNQGTCEPTSESPFYRCL-CPA--KFNGLLCHILD 1430
Score = 57.6 bits (133), Expect = 2e-07
Identities = 46/168 (27%), Positives = 69/168 (41%), Gaps = 12/168 (7%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
C C+D G+ C PG S + C+ NPC G C+D +G + C +CP
Sbjct: 650 CDSGTCLDKIDGYECACEPGYTGSMCNSNIDECAGNPCHNGGT-CEDGING-FTC-RCPE 706
Query: 79 GFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGR 138
G+H C +N C G +C ++ G KC C G+ G + PC
Sbjct: 707 GYHDPTCLSEVNECNSNPCVHG-ACRDSLNGYKC-DCDPGWSGTNCDINNNECESNPCVN 764
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSC 185
C K + C C G+ +G C +++EC PC + +C
Sbjct: 765 GGTC--KDMTSGIVCT-CREGF--SGPNCQTNINEC-ASNPCLNKGTC 806
Score = 57.2 bits (132), Expect = 2e-07
Identities = 47/166 (28%), Positives = 73/166 (43%), Gaps = 15/166 (9%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C D D + C G+ + + C+++PC G C D DG Y+C C G+ G+
Sbjct: 618 CQDPDNAYLCFCLKGTTGPNCEINLDDCASSPCDSG--TCLDKIDG-YECA-CEPGYTGS 673
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA-QKPCGRERRC 142
C N C G +CE+ G C CP GY D V + PC C
Sbjct: 674 MCNSNIDECAGNPCHNGGTCEDGINGFTC-RCPEGY-HDPTCLSEVNECNSNPC-VHGAC 730
Query: 143 MPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
+ + Y+C+ C G W+G C ++ +EC+ PC + +C++
Sbjct: 731 --RDSLNGYKCD-CDPG--WSGTNCDINNNECE-SNPCVNGGTCKD 770
Score = 56.8 bits (131), Expect = 3e-07
Identities = 53/174 (30%), Positives = 63/174 (36%), Gaps = 18/174 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRT---ACSANP--CFGGRVPCQDLPDGRYQCGK 75
G CVD + C CP T GQ C C P C G C + G Y C
Sbjct: 269 GGACVDGVNTYNCP-CPPEWT--GQYCTEDVDECQLMPNACQNGGT-CHNTHGG-YNC-V 322
Query: 76 CPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
C +G+ G C + CF G +C + C CP G G C P
Sbjct: 323 CVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYC-ECPHGRTGLLCHLNDAC-ISNP 380
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDL-IRPCDDLVSCRN 187
C C + C CPSGY G C D+DEC L PC+ C N
Sbjct: 381 CNEGSNCDTNPVNGKAICT-CPSGY--TGPACSQDVDECSLGANPCEHAGKCIN 431
Score = 50.4 bits (115), Expect = 2e-05
Identities = 84/332 (25%), Positives = 124/332 (37%), Gaps = 48/332 (14%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCF-GGRVPCQDLPDGRYQCGKCPSGFHG 82
C+D F+C PG + + C+++PC GR C D + +QC +CP+GF G
Sbjct: 467 CLDQIGEFQCMCMPGYEGVHCEVNTDECASSPCLHNGR--CLDKIN-EFQC-ECPTGFTG 522
Query: 83 NGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQKPCGRERR 141
+ + C + C G C + C C GY G + CD PC
Sbjct: 523 HLCQYDVDECASTPCKNGAKCLDGPNTYTC-VCTEGYTGTHCEVDIDECDPD-PC-HYGS 579
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C K + C C GY G+ C +++EC +PC +C++ +
Sbjct: 580 C--KDGVATFTCL-CRPGY--TGHHCETNINECS-SQPCRLRGTCQDPDNAYLCFCL--- 630
Query: 201 XXXSQGWRGTGNERRREHCVDVDECADGRA-NCPRGRLCVNTPQYPSNPVSSLQGSYICV 259
+G G E + C C G + G C P Y + +S
Sbjct: 631 ----KGTTGPNCEINLDDCAS-SPCDSGTCLDKIDGYECACEPGYTGSMCNSNIDECAGN 685
Query: 260 PC--GG-------HYYVNTTRPCFDPDSL--VKRCDPSYCRRFNAVCG---FGQKCVCNT 305
PC GG + DP L V C+ + C + C G KC C+
Sbjct: 686 PCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPC--VHGACRDSLNGYKCDCDP 743
Query: 306 GWTGNGTVCGLDRDLDGHPDEQLPC-NEPRCK 336
GW +GT C D++ + E PC N CK
Sbjct: 744 GW--SGTNC----DINNNECESNPCVNGGTCK 769
Score = 50.4 bits (115), Expect = 2e-05
Identities = 43/137 (31%), Positives = 57/137 (41%), Gaps = 16/137 (11%)
Query: 29 QGFRCERCPGSQTSDGQTCRT---ACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGV 85
+ F C CP + + GQTC C +PC G CQ+ G Y+C C +G+ G
Sbjct: 851 ESFSCV-CP-TAGAKGQTCEVDINECVLSPCRHG-ASCQNT-HGXYRC-HCQAGYSGRNC 905
Query: 86 ECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCM 143
E CR N C G SC + C C G+ G C+ + A PC C
Sbjct: 906 ETDIDDCRPNPCHNGGSCTDGINTAFC-DCLPGF--RGTFCEEDINECASDPCRNGANCT 962
Query: 144 PKSTSPYYECEGCPSGY 160
S Y C CP+G+
Sbjct: 963 DCVDS--YTCT-CPAGF 976
Score = 50.0 bits (114), Expect = 3e-05
Identities = 54/181 (29%), Positives = 76/181 (41%), Gaps = 29/181 (16%)
Query: 20 VGERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKC 76
+G C D RC CP T G C+ C ++PC G Q +Y+C +C
Sbjct: 1033 LGGTCQDGRGLHRCT-CPQGYT--GPNCQNLVHWCDSSPCKNGGKCWQT--HTQYRC-EC 1086
Query: 77 PSGFHGNGVECYRISCRANTCFQGVSCEE-TQYGPKC---GS-----CPTGYVGDGRQCQ 127
PSG+ G + +SC QGV Q+G C G+ C GY G C+
Sbjct: 1087 PSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGS--YCE 1144
Query: 128 HVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVS 184
+ D + PC C Y C+ C +GY +G C ++DEC L PC + +
Sbjct: 1145 DLVDECSPSPCQNGATCTDYLGG--YSCK-CVAGY--HGVNCSEEIDEC-LSHPCQNGGT 1198
Query: 185 C 185
C
Sbjct: 1199 C 1199
Score = 49.2 bits (112), Expect = 6e-05
Identities = 48/169 (28%), Positives = 68/169 (40%), Gaps = 20/169 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPS-G 79
C+D G++C C T G TC C+ +PC G C+ D CP+ G
Sbjct: 806 CIDDVAGYKCN-CLLPYT--GATCEVVLAPCAPSPCRNGG-ECRQSEDYESFSCVCPTAG 861
Query: 80 FHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCG 137
G E C + C G SC+ T +C C GY GR C+ D PC
Sbjct: 862 AKGQTCEVDINECVLSPCRHGASCQNTHGXYRC-HCQAGY--SGRNCETDIDDCRPNPCH 918
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSC 185
C + + C+ C G++ G C D++EC PC + +C
Sbjct: 919 NGGSCTDGINTAF--CD-CLPGFR--GTFCEEDINEC-ASDPCRNGANC 961
Score = 46.8 bits (106), Expect = 3e-04
Identities = 49/161 (30%), Positives = 64/161 (39%), Gaps = 33/161 (20%)
Query: 31 FRCERCPGSQTSDGQTCRTA--CSANPCFGGRVPCQDLP-DGRYQCGKCPSGFHG----- 82
++C RCP + G++C+ A C++NPC G Q LP + Y C CP FHG
Sbjct: 125 YKC-RCPPGWS--GKSCQQADPCASNPCANGG---QCLPFEASYIC-HCPPSFHGPTCRQ 177
Query: 83 NGVEC---YRISCRANTCFQGVS-----CEETQYGPKCG----SCPTGYVGDGRQCQHVC 130
+ EC R+ TC V C T GP C C +G C+
Sbjct: 178 DVNECGQKPRLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTG 237
Query: 131 DAQKPCGRERRCMPKSTSPYYE--CEGCPSGYQWNGYTCVD 169
D C C+P T E + CP NG CVD
Sbjct: 238 DVTHECA----CLPGFTGQNCEENIDDCPGNNCKNGGACVD 274
Score = 45.6 bits (103), Expect = 7e-04
Identities = 43/148 (29%), Positives = 58/148 (39%), Gaps = 20/148 (13%)
Query: 35 RCPGSQTSDGQTCR---TACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS 91
RC T G C CS +PC G C+ D ++C C GF G E
Sbjct: 203 RCVCRATHTGPNCERPYVPCSPSPCQNGGT-CRPTGDVTHECA-CLPGFTGQNCEENIDD 260
Query: 92 CRANTCFQGVSCEETQYGPKCGSCPTGYVG-----DGRQCQHVCDAQKPCGRERRCMPKS 146
C N C G +C + C CP + G D +CQ + +A C C +
Sbjct: 261 CPGNNCKNGGACVDGVNTYNC-PCPPEWTGQYCTEDVDECQLMPNA---CQNGGTC--HN 314
Query: 147 TSPYYECEGCPSGYQWNGYTCVD-MDEC 173
T Y C C +G W G C + +D+C
Sbjct: 315 THGGYNCV-CVNG--WTGEDCSENIDDC 339
Score = 43.2 bits (97), Expect = 0.004
Identities = 51/172 (29%), Positives = 74/172 (43%), Gaps = 25/172 (14%)
Query: 21 GERCVDTDQGFRCERCP-GSQTSDGQTCRTAC-------SANP-CFGGRVPCQDLPDGRY 71
G C+D ++C CP G+Q + C S +P CF C D G Y
Sbjct: 1196 GGTCLDLPNTYKCS-CPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGT-CVDQVGG-Y 1252
Query: 72 QCGKCPSGFHGNGVECYRISCRANTC-FQGV-SCEETQYGPKCGSCPTGYVGDGRQCQHV 129
C CP GF G E C +N C +G +C + C C G+ GR+C+ V
Sbjct: 1253 SC-TCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHC-ECRAGHT--GRRCESV 1308
Query: 130 CDA--QKPCGRERRC-MPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIR 177
+ KPC C + +T+ + C+ CP+G++ G TC D C +R
Sbjct: 1309 INGCKGKPCKNGGTCAVASNTARGFICK-CPAGFE--GATCENDARTCGSLR 1357
Score = 41.1 bits (92), Expect = 0.015
Identities = 42/168 (25%), Positives = 63/168 (37%), Gaps = 13/168 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G +C+D + C G + + C +PC G C+D + C C G+
Sbjct: 540 GAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG--SCKD-GVATFTC-LCRPGY 595
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
G+ E C + C +C++ C C G G + A PC
Sbjct: 596 TGHHCETNINECSSQPCRLRGTCQDPDNAYLC-FCLKGTTGPNCEINLDDCASSPCD-SG 653
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C+ K YEC C GY G C ++DEC PC + +C +
Sbjct: 654 TCLDKIDG--YEC-ACEPGY--TGSMCNSNIDEC-AGNPCHNGGTCED 695
>AY358892-1|AAQ89251.1| 723|Homo sapiens DLL1 protein.
Length = 723
Score = 74.1 bits (174), Expect = 2e-12
Identities = 52/171 (30%), Positives = 76/171 (44%), Gaps = 15/171 (8%)
Query: 21 GERCVDTDQG-FRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C +T QG + C PG + + C +PC G C DL + Y C CP G
Sbjct: 301 GATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGG-SCTDL-ENSYSC-TCPPG 357
Query: 80 FHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCG 137
F+G E ++C CF G C ++ G CP GY G C+ D + PC
Sbjct: 358 FYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGY--SGFNCEKKIDYCSSSPCS 415
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRPCDDLVSCRN 187
+C+ + Y C C +G+ +G C D +D+C PC + +CR+
Sbjct: 416 NGAKCVDLGDA--YLCR-CQAGF--SGRHCDDNVDDC-ASSPCANGGTCRD 460
Score = 44.0 bits (99), Expect = 0.002
Identities = 33/118 (27%), Positives = 47/118 (39%), Gaps = 12/118 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G +CVD + C RC + G+ C C+++PC G C+D + + C CP
Sbjct: 417 GAKCVDLGDAYLC-RCQAGFS--GRHCDDNVDDCASSPCANGGT-CRDGVND-FSC-TCP 470
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
G+ G C C G +C E + C C GY G CQ + P
Sbjct: 471 PGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVC-ECARGY--GGPNCQFLLPELPP 525
>AL078605-2|CAB89569.1| 723|Homo sapiens delta-like 1 (Drosophila)
protein.
Length = 723
Score = 74.1 bits (174), Expect = 2e-12
Identities = 52/171 (30%), Positives = 76/171 (44%), Gaps = 15/171 (8%)
Query: 21 GERCVDTDQG-FRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C +T QG + C PG + + C +PC G C DL + Y C CP G
Sbjct: 301 GATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGG-SCTDL-ENSYSC-TCPPG 357
Query: 80 FHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCG 137
F+G E ++C CF G C ++ G CP GY G C+ D + PC
Sbjct: 358 FYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGY--SGFNCEKKIDYCSSSPCS 415
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRPCDDLVSCRN 187
+C+ + Y C C +G+ +G C D +D+C PC + +CR+
Sbjct: 416 NGAKCVDLGDA--YLCR-CQAGF--SGRHCDDNVDDC-ASSPCANGGTCRD 460
Score = 44.0 bits (99), Expect = 0.002
Identities = 33/118 (27%), Positives = 47/118 (39%), Gaps = 12/118 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G +CVD + C RC + G+ C C+++PC G C+D + + C CP
Sbjct: 417 GAKCVDLGDAYLC-RCQAGFS--GRHCDDNVDDCASSPCANGGT-CRDGVND-FSC-TCP 470
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
G+ G C C G +C E + C C GY G CQ + P
Sbjct: 471 PGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVC-ECARGY--GGPNCQFLLPELPP 525
>AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein.
Length = 723
Score = 74.1 bits (174), Expect = 2e-12
Identities = 52/171 (30%), Positives = 76/171 (44%), Gaps = 15/171 (8%)
Query: 21 GERCVDTDQG-FRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C +T QG + C PG + + C +PC G C DL + Y C CP G
Sbjct: 301 GATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGG-SCTDL-ENSYSC-TCPPG 357
Query: 80 FHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCG 137
F+G E ++C CF G C ++ G CP GY G C+ D + PC
Sbjct: 358 FYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGY--SGFNCEKKIDYCSSSPCS 415
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRPCDDLVSCRN 187
+C+ + Y C C +G+ +G C D +D+C PC + +CR+
Sbjct: 416 NGAKCVDLGDA--YLCR-CQAGF--SGRHCDDNVDDC-ASSPCANGGTCRD 460
Score = 47.2 bits (107), Expect = 2e-04
Identities = 34/118 (28%), Positives = 48/118 (40%), Gaps = 12/118 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G +CVD + C RC + G+ C C+++PC G C+D + + C CP
Sbjct: 417 GAKCVDLGDAYLC-RCQAGFS--GRHCDDNVDDCASSPCANGGT-CRDGVND-FSC-TCP 470
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
G+ G C C G +C E +G C C GY G CQ + P
Sbjct: 471 PGYTGRNCSAPVSRCEHAPCHNGATCHERGHGYVC-ECARGY--GGPNCQFLLPELPP 525
>AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein
protein.
Length = 723
Score = 74.1 bits (174), Expect = 2e-12
Identities = 52/171 (30%), Positives = 76/171 (44%), Gaps = 15/171 (8%)
Query: 21 GERCVDTDQG-FRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C +T QG + C PG + + C +PC G C DL + Y C CP G
Sbjct: 301 GATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGG-SCTDL-ENSYSC-TCPPG 357
Query: 80 FHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCG 137
F+G E ++C CF G C ++ G CP GY G C+ D + PC
Sbjct: 358 FYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGY--SGFNCEKKIDYCSSSPCS 415
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRPCDDLVSCRN 187
+C+ + Y C C +G+ +G C D +D+C PC + +CR+
Sbjct: 416 NGAKCVDLGDA--YLCR-CQAGF--SGRHCDDNVDDC-ASSPCANGGTCRD 460
Score = 43.6 bits (98), Expect = 0.003
Identities = 32/118 (27%), Positives = 47/118 (39%), Gaps = 12/118 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G +CVD + C RC + G+ C C+++PC G C+D + + C CP
Sbjct: 417 GAKCVDLGDAYLC-RCQAGFS--GRHCDDNVDDCASSPCANGGT-CRDGVND-FSC-TCP 470
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
G+ G C C G +C + +G C C Y G CQ + P
Sbjct: 471 PGYTGRNCSAPVSRCEHAPCHNGATCHQRGHGYVC-ECARSY--GGPNCQFLLPELPP 525
>AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein.
Length = 723
Score = 74.1 bits (174), Expect = 2e-12
Identities = 52/171 (30%), Positives = 76/171 (44%), Gaps = 15/171 (8%)
Query: 21 GERCVDTDQG-FRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C +T QG + C PG + + C +PC G C DL + Y C CP G
Sbjct: 301 GATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGG-SCTDL-ENSYSC-TCPPG 357
Query: 80 FHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCG 137
F+G E ++C CF G C ++ G CP GY G C+ D + PC
Sbjct: 358 FYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGY--SGFNCEKKIDYCSSSPCS 415
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRPCDDLVSCRN 187
+C+ + Y C C +G+ +G C D +D+C PC + +CR+
Sbjct: 416 NGAKCVDLGDA--YLCR-CQAGF--SGRHCDDNVDDC-ASSPCANGGTCRD 460
Score = 47.2 bits (107), Expect = 2e-04
Identities = 34/118 (28%), Positives = 48/118 (40%), Gaps = 12/118 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G +CVD + C RC + G+ C C+++PC G C+D + + C CP
Sbjct: 417 GAKCVDLGDAYLC-RCQAGFS--GRHCDDNVDDCASSPCANGGT-CRDGVND-FSC-TCP 470
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
G+ G C C G +C E +G C C GY G CQ + P
Sbjct: 471 PGYTGRNCSAPVSRCEHAPCHNGATCHERGHGYVC-ECARGY--GGPNCQFLLPELPP 525
>AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precursor
protein.
Length = 1406
Score = 72.5 bits (170), Expect = 5e-12
Identities = 51/162 (31%), Positives = 64/162 (39%), Gaps = 9/162 (5%)
Query: 28 DQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVEC 87
D C + D + C +NPC G C + P R KCP G+ G E
Sbjct: 51 DNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT-CVNTPGERSFLCKCPPGYSGTICET 109
Query: 88 YRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKST 147
SC N+C G C + P C CP GY G + H A PC C
Sbjct: 110 TIGSCGKNSCQHGGICHQDPIYPVC-ICPAGYAGRFCEIDHDECASSPCQNGAVCQDGID 168
Query: 148 SPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNE 188
Y C C GYQ G C +++DEC PC + +C NE
Sbjct: 169 G--YSC-FCVPGYQ--GRHCDLEVDEC-ASDPCKNEATCLNE 204
Score = 62.5 bits (145), Expect = 6e-09
Identities = 50/186 (26%), Positives = 75/186 (40%), Gaps = 26/186 (13%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D + C+ PG + C++ PC G + C D + RY C SGF
Sbjct: 236 GATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGL-CVD-GENRYSCNCTGSGF 293
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ---HVCDAQKPCG 137
G E C + C +CE++ C C GY G QC+ + C++ PC
Sbjct: 294 TGTHCETLMPLCWSKPCHNNATCEDSVDNYTC-HCWPGYT--GAQCEIDLNECNS-NPCQ 349
Query: 138 RERRCMPKSTSPYY-ECEGCPSGYQW---NGYTCV------------DMDECDLIRPCDD 181
C+ S+ Y G PS + + +GY C+ D++EC PC +
Sbjct: 350 SNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECS-SNPCQN 408
Query: 182 LVSCRN 187
+C N
Sbjct: 409 GGTCEN 414
Score = 55.6 bits (128), Expect = 7e-07
Identities = 41/167 (24%), Positives = 63/167 (37%), Gaps = 8/167 (4%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D G+ C PG Q C+++PC ++ GRY C CP +
Sbjct: 160 GAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEI--GRYTC-ICPHNY 216
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
G E C + C G +C++ C C G++GD + A +PC
Sbjct: 217 SGVNCELEIDECWSQPCLNGATCQDALGAYFC-DCAPGFLGDHCELNTDECASQPCLHGG 275
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRN 187
C+ Y C SG+ G C + +PC + +C +
Sbjct: 276 LCVDGENR--YSCNCTGSGF--TGTHCETLMPLCWSKPCHNNATCED 318
Score = 42.7 bits (96), Expect = 0.005
Identities = 39/137 (28%), Positives = 51/137 (37%), Gaps = 19/137 (13%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGP 110
C++NPC G C+D+ Y C CP G+ G E C +N C G +C +
Sbjct: 1143 CNSNPCLHGG-NCEDIYSS-YHCS-CPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAY 1198
Query: 111 KCGSCPTGYVG-----DGRQCQ-HVCDAQKPC-----GRERRCMPKSTSPYYECEGCPS- 158
C +C GY G D CQ H C C G C T + PS
Sbjct: 1199 HC-TCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
Query: 159 --GYQWNGYTCVDMDEC 173
G + TC + C
Sbjct: 1258 VCGNEKTNLTCYNGGNC 1274
Score = 34.3 bits (75), Expect = 1.7
Identities = 35/127 (27%), Positives = 49/127 (38%), Gaps = 15/127 (11%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
C+ C D + C PG + + C ++ C G C +G Y C C
Sbjct: 1186 CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGAT-CISHTNG-YSC-LCFG 1242
Query: 79 GFHGNGVECYRIS---C---RAN-TCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
F G R+ C + N TC+ G +C E Q KC C G+ G+ C+ D
Sbjct: 1243 NFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKC-MCRPGFTGE--WCEKDID 1299
Query: 132 --AQKPC 136
A PC
Sbjct: 1300 ECASDPC 1306
>AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precursor
protein.
Length = 1376
Score = 72.5 bits (170), Expect = 5e-12
Identities = 51/162 (31%), Positives = 64/162 (39%), Gaps = 9/162 (5%)
Query: 28 DQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVEC 87
D C + D + C +NPC G C + P R KCP G+ G E
Sbjct: 51 DNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT-CVNTPGERSFLCKCPPGYSGTICET 109
Query: 88 YRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKST 147
SC N+C G C + P C CP GY G + H A PC C
Sbjct: 110 TIGSCGKNSCQHGGICHQDPIYPVC-ICPAGYAGRFCEIDHDECASSPCQNGAVCQDGID 168
Query: 148 SPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNE 188
Y C C GYQ G C +++DEC PC + +C NE
Sbjct: 169 G--YSC-FCVPGYQ--GRHCDLEVDEC-ASDPCKNEATCLNE 204
Score = 62.5 bits (145), Expect = 6e-09
Identities = 50/186 (26%), Positives = 75/186 (40%), Gaps = 26/186 (13%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D + C+ PG + C++ PC G + C D + RY C SGF
Sbjct: 236 GATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGL-CVD-GENRYSCNCTGSGF 293
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ---HVCDAQKPCG 137
G E C + C +CE++ C C GY G QC+ + C++ PC
Sbjct: 294 TGTHCETLMPLCWSKPCHNNATCEDSVDNYTC-HCWPGYT--GAQCEIDLNECNS-NPCQ 349
Query: 138 RERRCMPKSTSPYY-ECEGCPSGYQW---NGYTCV------------DMDECDLIRPCDD 181
C+ S+ Y G PS + + +GY C+ D++EC PC +
Sbjct: 350 SNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECS-SNPCQN 408
Query: 182 LVSCRN 187
+C N
Sbjct: 409 GGTCEN 414
Score = 55.6 bits (128), Expect = 7e-07
Identities = 41/167 (24%), Positives = 63/167 (37%), Gaps = 8/167 (4%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D G+ C PG Q C+++PC ++ GRY C CP +
Sbjct: 160 GAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEI--GRYTC-ICPHNY 216
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
G E C + C G +C++ C C G++GD + A +PC
Sbjct: 217 SGVNCELEIDECWSQPCLNGATCQDALGAYFC-DCAPGFLGDHCELNTDECASQPCLHGG 275
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRN 187
C+ Y C SG+ G C + +PC + +C +
Sbjct: 276 LCVDGENR--YSCNCTGSGF--TGTHCETLMPLCWSKPCHNNATCED 318
Score = 42.7 bits (96), Expect = 0.005
Identities = 39/137 (28%), Positives = 51/137 (37%), Gaps = 19/137 (13%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGP 110
C++NPC G C+D+ Y C CP G+ G E C +N C G +C +
Sbjct: 1143 CNSNPCLHGG-NCEDIYSS-YHCS-CPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAY 1198
Query: 111 KCGSCPTGYVG-----DGRQCQ-HVCDAQKPC-----GRERRCMPKSTSPYYECEGCPS- 158
C +C GY G D CQ H C C G C T + PS
Sbjct: 1199 HC-TCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
Query: 159 --GYQWNGYTCVDMDEC 173
G + TC + C
Sbjct: 1258 VCGNEKTNLTCYNGGNC 1274
Score = 34.3 bits (75), Expect = 1.7
Identities = 35/127 (27%), Positives = 49/127 (38%), Gaps = 15/127 (11%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
C+ C D + C PG + + C ++ C G C +G Y C C
Sbjct: 1186 CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGAT-CISHTNG-YSC-LCFG 1242
Query: 79 GFHGNGVECYRIS---C---RAN-TCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
F G R+ C + N TC+ G +C E Q KC C G+ G+ C+ D
Sbjct: 1243 NFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKC-MCRPGFTGE--WCEKDID 1299
Query: 132 --AQKPC 136
A PC
Sbjct: 1300 ECASDPC 1306
>AL513325-3|CAH72584.1| 1406|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1406
Score = 72.5 bits (170), Expect = 5e-12
Identities = 51/162 (31%), Positives = 64/162 (39%), Gaps = 9/162 (5%)
Query: 28 DQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVEC 87
D C + D + C +NPC G C + P R KCP G+ G E
Sbjct: 51 DNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT-CVNTPGERSFLCKCPPGYSGTICET 109
Query: 88 YRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKST 147
SC N+C G C + P C CP GY G + H A PC C
Sbjct: 110 TIGSCGKNSCQHGGICHQDPIYPVC-ICPAGYAGRFCEIDHDECASSPCQNGAVCQDGID 168
Query: 148 SPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNE 188
Y C C GYQ G C +++DEC PC + +C NE
Sbjct: 169 G--YSC-FCVPGYQ--GRHCDLEVDEC-ASDPCKNEATCLNE 204
Score = 62.5 bits (145), Expect = 6e-09
Identities = 50/186 (26%), Positives = 75/186 (40%), Gaps = 26/186 (13%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D + C+ PG + C++ PC G + C D + RY C SGF
Sbjct: 236 GATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGL-CVD-GENRYSCNCTGSGF 293
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ---HVCDAQKPCG 137
G E C + C +CE++ C C GY G QC+ + C++ PC
Sbjct: 294 TGTHCETLMPLCWSKPCHNNATCEDSVDNYTC-HCWPGYT--GAQCEIDLNECNS-NPCQ 349
Query: 138 RERRCMPKSTSPYY-ECEGCPSGYQW---NGYTCV------------DMDECDLIRPCDD 181
C+ S+ Y G PS + + +GY C+ D++EC PC +
Sbjct: 350 SNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECS-SNPCQN 408
Query: 182 LVSCRN 187
+C N
Sbjct: 409 GGTCEN 414
Score = 55.6 bits (128), Expect = 7e-07
Identities = 41/167 (24%), Positives = 63/167 (37%), Gaps = 8/167 (4%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D G+ C PG Q C+++PC ++ GRY C CP +
Sbjct: 160 GAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEI--GRYTC-ICPHNY 216
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
G E C + C G +C++ C C G++GD + A +PC
Sbjct: 217 SGVNCELEIDECWSQPCLNGATCQDALGAYFC-DCAPGFLGDHCELNTDECASQPCLHGG 275
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRN 187
C+ Y C SG+ G C + +PC + +C +
Sbjct: 276 LCVDGENR--YSCNCTGSGF--TGTHCETLMPLCWSKPCHNNATCED 318
Score = 42.7 bits (96), Expect = 0.005
Identities = 39/137 (28%), Positives = 51/137 (37%), Gaps = 19/137 (13%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGP 110
C++NPC G C+D+ Y C CP G+ G E C +N C G +C +
Sbjct: 1143 CNSNPCLHGG-NCEDIYSS-YHCS-CPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAY 1198
Query: 111 KCGSCPTGYVG-----DGRQCQ-HVCDAQKPC-----GRERRCMPKSTSPYYECEGCPS- 158
C +C GY G D CQ H C C G C T + PS
Sbjct: 1199 HC-TCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
Query: 159 --GYQWNGYTCVDMDEC 173
G + TC + C
Sbjct: 1258 VCGNEKTNLTCYNGGNC 1274
Score = 34.3 bits (75), Expect = 1.7
Identities = 35/127 (27%), Positives = 49/127 (38%), Gaps = 15/127 (11%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
C+ C D + C PG + + C ++ C G C +G Y C C
Sbjct: 1186 CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGAT-CISHTNG-YSC-LCFG 1242
Query: 79 GFHGNGVECYRIS---C---RAN-TCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
F G R+ C + N TC+ G +C E Q KC C G+ G+ C+ D
Sbjct: 1243 NFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKC-MCRPGFTGE--WCEKDID 1299
Query: 132 --AQKPC 136
A PC
Sbjct: 1300 ECASDPC 1306
>AL513325-2|CAM17208.1| 1294|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1294
Score = 72.5 bits (170), Expect = 5e-12
Identities = 51/162 (31%), Positives = 64/162 (39%), Gaps = 9/162 (5%)
Query: 28 DQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVEC 87
D C + D + C +NPC G C + P R KCP G+ G E
Sbjct: 51 DNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT-CVNTPGERSFLCKCPPGYSGTICET 109
Query: 88 YRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKST 147
SC N+C G C + P C CP GY G + H A PC C
Sbjct: 110 TIGSCGKNSCQHGGICHQDPIYPVC-ICPAGYAGRFCEIDHDECASSPCQNGAVCQDGID 168
Query: 148 SPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNE 188
Y C C GYQ G C +++DEC PC + +C NE
Sbjct: 169 G--YSC-FCVPGYQ--GRHCDLEVDEC-ASDPCKNEATCLNE 204
Score = 42.7 bits (96), Expect = 0.005
Identities = 39/137 (28%), Positives = 51/137 (37%), Gaps = 19/137 (13%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGP 110
C++NPC G C+D+ Y C CP G+ G E C +N C G +C +
Sbjct: 1031 CNSNPCLHGG-NCEDIYSS-YHCS-CPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAY 1086
Query: 111 KCGSCPTGYVG-----DGRQCQ-HVCDAQKPC-----GRERRCMPKSTSPYYECEGCPS- 158
C +C GY G D CQ H C C G C T + PS
Sbjct: 1087 HC-TCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1145
Query: 159 --GYQWNGYTCVDMDEC 173
G + TC + C
Sbjct: 1146 VCGNEKTNLTCYNGGNC 1162
Score = 34.3 bits (75), Expect = 1.7
Identities = 35/127 (27%), Positives = 49/127 (38%), Gaps = 15/127 (11%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
C+ C D + C PG + + C ++ C G C +G Y C C
Sbjct: 1074 CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGAT-CISHTNG-YSC-LCFG 1130
Query: 79 GFHGNGVECYRIS---C---RAN-TCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
F G R+ C + N TC+ G +C E Q KC C G+ G+ C+ D
Sbjct: 1131 NFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKC-MCRPGFTGE--WCEKDID 1187
Query: 132 --AQKPC 136
A PC
Sbjct: 1188 ECASDPC 1194
>AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1294
Score = 72.5 bits (170), Expect = 5e-12
Identities = 51/162 (31%), Positives = 64/162 (39%), Gaps = 9/162 (5%)
Query: 28 DQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVEC 87
D C + D + C +NPC G C + P R KCP G+ G E
Sbjct: 51 DNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT-CVNTPGERSFLCKCPPGYSGTICET 109
Query: 88 YRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKST 147
SC N+C G C + P C CP GY G + H A PC C
Sbjct: 110 TIGSCGKNSCQHGGICHQDPIYPVC-ICPAGYAGRFCEIDHDECASSPCQNGAVCQDGID 168
Query: 148 SPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNE 188
Y C C GYQ G C +++DEC PC + +C NE
Sbjct: 169 G--YSC-FCVPGYQ--GRHCDLEVDEC-ASDPCKNEATCLNE 204
Score = 42.7 bits (96), Expect = 0.005
Identities = 39/137 (28%), Positives = 51/137 (37%), Gaps = 19/137 (13%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGP 110
C++NPC G C+D+ Y C CP G+ G E C +N C G +C +
Sbjct: 1031 CNSNPCLHGG-NCEDIYSS-YHCS-CPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAY 1086
Query: 111 KCGSCPTGYVG-----DGRQCQ-HVCDAQKPC-----GRERRCMPKSTSPYYECEGCPS- 158
C +C GY G D CQ H C C G C T + PS
Sbjct: 1087 HC-TCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1145
Query: 159 --GYQWNGYTCVDMDEC 173
G + TC + C
Sbjct: 1146 VCGNEKTNLTCYNGGNC 1162
Score = 34.3 bits (75), Expect = 1.7
Identities = 35/127 (27%), Positives = 49/127 (38%), Gaps = 15/127 (11%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
C+ C D + C PG + + C ++ C G C +G Y C C
Sbjct: 1074 CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGAT-CISHTNG-YSC-LCFG 1130
Query: 79 GFHGNGVECYRIS---C---RAN-TCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
F G R+ C + N TC+ G +C E Q KC C G+ G+ C+ D
Sbjct: 1131 NFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKC-MCRPGFTGE--WCEKDID 1187
Query: 132 --AQKPC 136
A PC
Sbjct: 1188 ECASDPC 1194
>AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1406
Score = 72.5 bits (170), Expect = 5e-12
Identities = 51/162 (31%), Positives = 64/162 (39%), Gaps = 9/162 (5%)
Query: 28 DQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVEC 87
D C + D + C +NPC G C + P R KCP G+ G E
Sbjct: 51 DNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT-CVNTPGERSFLCKCPPGYSGTICET 109
Query: 88 YRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKST 147
SC N+C G C + P C CP GY G + H A PC C
Sbjct: 110 TIGSCGKNSCQHGGICHQDPIYPVC-ICPAGYAGRFCEIDHDECASSPCQNGAVCQDGID 168
Query: 148 SPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNE 188
Y C C GYQ G C +++DEC PC + +C NE
Sbjct: 169 G--YSC-FCVPGYQ--GRHCDLEVDEC-ASDPCKNEATCLNE 204
Score = 62.5 bits (145), Expect = 6e-09
Identities = 50/186 (26%), Positives = 75/186 (40%), Gaps = 26/186 (13%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D + C+ PG + C++ PC G + C D + RY C SGF
Sbjct: 236 GATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGL-CVD-GENRYSCNCTGSGF 293
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ---HVCDAQKPCG 137
G E C + C +CE++ C C GY G QC+ + C++ PC
Sbjct: 294 TGTHCETLMPLCWSKPCHNNATCEDSVDNYTC-HCWPGYT--GAQCEIDLNECNS-NPCQ 349
Query: 138 RERRCMPKSTSPYY-ECEGCPSGYQW---NGYTCV------------DMDECDLIRPCDD 181
C+ S+ Y G PS + + +GY C+ D++EC PC +
Sbjct: 350 SNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECS-SNPCQN 408
Query: 182 LVSCRN 187
+C N
Sbjct: 409 GGTCEN 414
Score = 55.6 bits (128), Expect = 7e-07
Identities = 41/167 (24%), Positives = 63/167 (37%), Gaps = 8/167 (4%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D G+ C PG Q C+++PC ++ GRY C CP +
Sbjct: 160 GAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEI--GRYTC-ICPHNY 216
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
G E C + C G +C++ C C G++GD + A +PC
Sbjct: 217 SGVNCELEIDECWSQPCLNGATCQDALGAYFC-DCAPGFLGDHCELNTDECASQPCLHGG 275
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRN 187
C+ Y C SG+ G C + +PC + +C +
Sbjct: 276 LCVDGENR--YSCNCTGSGF--TGTHCETLMPLCWSKPCHNNATCED 318
Score = 42.7 bits (96), Expect = 0.005
Identities = 39/137 (28%), Positives = 51/137 (37%), Gaps = 19/137 (13%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGP 110
C++NPC G C+D+ Y C CP G+ G E C +N C G +C +
Sbjct: 1143 CNSNPCLHGG-NCEDIYSS-YHCS-CPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAY 1198
Query: 111 KCGSCPTGYVG-----DGRQCQ-HVCDAQKPC-----GRERRCMPKSTSPYYECEGCPS- 158
C +C GY G D CQ H C C G C T + PS
Sbjct: 1199 HC-TCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
Query: 159 --GYQWNGYTCVDMDEC 173
G + TC + C
Sbjct: 1258 VCGNEKTNLTCYNGGNC 1274
Score = 34.3 bits (75), Expect = 1.7
Identities = 35/127 (27%), Positives = 49/127 (38%), Gaps = 15/127 (11%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
C+ C D + C PG + + C ++ C G C +G Y C C
Sbjct: 1186 CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGAT-CISHTNG-YSC-LCFG 1242
Query: 79 GFHGNGVECYRIS---C---RAN-TCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
F G R+ C + N TC+ G +C E Q KC C G+ G+ C+ D
Sbjct: 1243 NFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKC-MCRPGFTGE--WCEKDID 1299
Query: 132 --AQKPC 136
A PC
Sbjct: 1300 ECASDPC 1306
>AL136322-4|CAI16646.1| 1406|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1406
Score = 72.5 bits (170), Expect = 5e-12
Identities = 51/162 (31%), Positives = 64/162 (39%), Gaps = 9/162 (5%)
Query: 28 DQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVEC 87
D C + D + C +NPC G C + P R KCP G+ G E
Sbjct: 51 DNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT-CVNTPGERSFLCKCPPGYSGTICET 109
Query: 88 YRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKST 147
SC N+C G C + P C CP GY G + H A PC C
Sbjct: 110 TIGSCGKNSCQHGGICHQDPIYPVC-ICPAGYAGRFCEIDHDECASSPCQNGAVCQDGID 168
Query: 148 SPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNE 188
Y C C GYQ G C +++DEC PC + +C NE
Sbjct: 169 G--YSC-FCVPGYQ--GRHCDLEVDEC-ASDPCKNEATCLNE 204
Score = 62.5 bits (145), Expect = 6e-09
Identities = 50/186 (26%), Positives = 75/186 (40%), Gaps = 26/186 (13%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D + C+ PG + C++ PC G + C D + RY C SGF
Sbjct: 236 GATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGL-CVD-GENRYSCNCTGSGF 293
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ---HVCDAQKPCG 137
G E C + C +CE++ C C GY G QC+ + C++ PC
Sbjct: 294 TGTHCETLMPLCWSKPCHNNATCEDSVDNYTC-HCWPGYT--GAQCEIDLNECNS-NPCQ 349
Query: 138 RERRCMPKSTSPYY-ECEGCPSGYQW---NGYTCV------------DMDECDLIRPCDD 181
C+ S+ Y G PS + + +GY C+ D++EC PC +
Sbjct: 350 SNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECS-SNPCQN 408
Query: 182 LVSCRN 187
+C N
Sbjct: 409 GGTCEN 414
Score = 55.6 bits (128), Expect = 7e-07
Identities = 41/167 (24%), Positives = 63/167 (37%), Gaps = 8/167 (4%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D G+ C PG Q C+++PC ++ GRY C CP +
Sbjct: 160 GAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEI--GRYTC-ICPHNY 216
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
G E C + C G +C++ C C G++GD + A +PC
Sbjct: 217 SGVNCELEIDECWSQPCLNGATCQDALGAYFC-DCAPGFLGDHCELNTDECASQPCLHGG 275
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRN 187
C+ Y C SG+ G C + +PC + +C +
Sbjct: 276 LCVDGENR--YSCNCTGSGF--TGTHCETLMPLCWSKPCHNNATCED 318
Score = 42.7 bits (96), Expect = 0.005
Identities = 39/137 (28%), Positives = 51/137 (37%), Gaps = 19/137 (13%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGP 110
C++NPC G C+D+ Y C CP G+ G E C +N C G +C +
Sbjct: 1143 CNSNPCLHGG-NCEDIYSS-YHCS-CPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAY 1198
Query: 111 KCGSCPTGYVG-----DGRQCQ-HVCDAQKPC-----GRERRCMPKSTSPYYECEGCPS- 158
C +C GY G D CQ H C C G C T + PS
Sbjct: 1199 HC-TCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
Query: 159 --GYQWNGYTCVDMDEC 173
G + TC + C
Sbjct: 1258 VCGNEKTNLTCYNGGNC 1274
Score = 34.3 bits (75), Expect = 1.7
Identities = 35/127 (27%), Positives = 49/127 (38%), Gaps = 15/127 (11%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
C+ C D + C PG + + C ++ C G C +G Y C C
Sbjct: 1186 CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGAT-CISHTNG-YSC-LCFG 1242
Query: 79 GFHGNGVECYRIS---C---RAN-TCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
F G R+ C + N TC+ G +C E Q KC C G+ G+ C+ D
Sbjct: 1243 NFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKC-MCRPGFTGE--WCEKDID 1299
Query: 132 --AQKPC 136
A PC
Sbjct: 1300 ECASDPC 1306
>AL136322-3|CAM23328.1| 1294|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1294
Score = 72.5 bits (170), Expect = 5e-12
Identities = 51/162 (31%), Positives = 64/162 (39%), Gaps = 9/162 (5%)
Query: 28 DQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVEC 87
D C + D + C +NPC G C + P R KCP G+ G E
Sbjct: 51 DNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT-CVNTPGERSFLCKCPPGYSGTICET 109
Query: 88 YRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKST 147
SC N+C G C + P C CP GY G + H A PC C
Sbjct: 110 TIGSCGKNSCQHGGICHQDPIYPVC-ICPAGYAGRFCEIDHDECASSPCQNGAVCQDGID 168
Query: 148 SPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNE 188
Y C C GYQ G C +++DEC PC + +C NE
Sbjct: 169 G--YSC-FCVPGYQ--GRHCDLEVDEC-ASDPCKNEATCLNE 204
Score = 42.7 bits (96), Expect = 0.005
Identities = 39/137 (28%), Positives = 51/137 (37%), Gaps = 19/137 (13%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGP 110
C++NPC G C+D+ Y C CP G+ G E C +N C G +C +
Sbjct: 1031 CNSNPCLHGG-NCEDIYSS-YHCS-CPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAY 1086
Query: 111 KCGSCPTGYVG-----DGRQCQ-HVCDAQKPC-----GRERRCMPKSTSPYYECEGCPS- 158
C +C GY G D CQ H C C G C T + PS
Sbjct: 1087 HC-TCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1145
Query: 159 --GYQWNGYTCVDMDEC 173
G + TC + C
Sbjct: 1146 VCGNEKTNLTCYNGGNC 1162
Score = 34.3 bits (75), Expect = 1.7
Identities = 35/127 (27%), Positives = 49/127 (38%), Gaps = 15/127 (11%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
C+ C D + C PG + + C ++ C G C +G Y C C
Sbjct: 1074 CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGAT-CISHTNG-YSC-LCFG 1130
Query: 79 GFHGNGVECYRIS---C---RAN-TCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
F G R+ C + N TC+ G +C E Q KC C G+ G+ C+ D
Sbjct: 1131 NFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKC-MCRPGFTGE--WCEKDID 1187
Query: 132 --AQKPC 136
A PC
Sbjct: 1188 ECASDPC 1194
>AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1
(alternative protein) protein.
Length = 1294
Score = 72.5 bits (170), Expect = 5e-12
Identities = 51/162 (31%), Positives = 64/162 (39%), Gaps = 9/162 (5%)
Query: 28 DQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVEC 87
D C + D + C +NPC G C + P R KCP G+ G E
Sbjct: 51 DNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT-CVNTPGERSFLCKCPPGYSGTICET 109
Query: 88 YRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKST 147
SC N+C G C + P C CP GY G + H A PC C
Sbjct: 110 TIGSCGKNSCQHGGICHQDPIYPVC-ICPAGYAGRFCEIDHDECASSPCQNGAVCQDGID 168
Query: 148 SPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNE 188
Y C C GYQ G C +++DEC PC + +C NE
Sbjct: 169 G--YSC-FCVPGYQ--GRHCDLEVDEC-ASDPCKNEATCLNE 204
Score = 42.7 bits (96), Expect = 0.005
Identities = 39/137 (28%), Positives = 51/137 (37%), Gaps = 19/137 (13%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGP 110
C++NPC G C+D+ Y C CP G+ G E C +N C G +C +
Sbjct: 1031 CNSNPCLHGG-NCEDIYSS-YHCS-CPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAY 1086
Query: 111 KCGSCPTGYVG-----DGRQCQ-HVCDAQKPC-----GRERRCMPKSTSPYYECEGCPS- 158
C +C GY G D CQ H C C G C T + PS
Sbjct: 1087 HC-TCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1145
Query: 159 --GYQWNGYTCVDMDEC 173
G + TC + C
Sbjct: 1146 VCGNEKTNLTCYNGGNC 1162
Score = 34.3 bits (75), Expect = 1.7
Identities = 35/127 (27%), Positives = 49/127 (38%), Gaps = 15/127 (11%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
C+ C D + C PG + + C ++ C G C +G Y C C
Sbjct: 1074 CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGAT-CISHTNG-YSC-LCFG 1130
Query: 79 GFHGNGVECYRIS---C---RAN-TCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
F G R+ C + N TC+ G +C E Q KC C G+ G+ C+ D
Sbjct: 1131 NFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKC-MCRPGFTGE--WCEKDID 1187
Query: 132 --AQKPC 136
A PC
Sbjct: 1188 ECASDPC 1194
>AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein.
Length = 1376
Score = 72.5 bits (170), Expect = 5e-12
Identities = 51/162 (31%), Positives = 64/162 (39%), Gaps = 9/162 (5%)
Query: 28 DQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVEC 87
D C + D + C +NPC G C + P R KCP G+ G E
Sbjct: 51 DNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT-CVNTPGERSFLCKCPPGYSGTICET 109
Query: 88 YRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKST 147
SC N+C G C + P C CP GY G + H A PC C
Sbjct: 110 TIGSCGKNSCQHGGICHQDPIYPVC-ICPAGYAGRFCEIDHDECASSPCQNGAVCQDGID 168
Query: 148 SPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNE 188
Y C C GYQ G C +++DEC PC + +C NE
Sbjct: 169 G--YSC-FCVPGYQ--GRHCDLEVDEC-ASDPCKNEATCLNE 204
Score = 62.5 bits (145), Expect = 6e-09
Identities = 50/186 (26%), Positives = 75/186 (40%), Gaps = 26/186 (13%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D + C+ PG + C++ PC G + C D + RY C SGF
Sbjct: 236 GATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGL-CVD-GENRYSCNCTGSGF 293
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ---HVCDAQKPCG 137
G E C + C +CE++ C C GY G QC+ + C++ PC
Sbjct: 294 TGTHCETLMPLCWSKPCHNNATCEDSVDNYTC-HCWPGYT--GAQCEIDLNECNS-NPCQ 349
Query: 138 RERRCMPKSTSPYY-ECEGCPSGYQW---NGYTCV------------DMDECDLIRPCDD 181
C+ S+ Y G PS + + +GY C+ D++EC PC +
Sbjct: 350 SNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECS-SNPCQN 408
Query: 182 LVSCRN 187
+C N
Sbjct: 409 GGTCEN 414
Score = 55.6 bits (128), Expect = 7e-07
Identities = 41/167 (24%), Positives = 63/167 (37%), Gaps = 8/167 (4%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D G+ C PG Q C+++PC ++ GRY C CP +
Sbjct: 160 GAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEI--GRYTC-ICPHNY 216
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
G E C + C G +C++ C C G++GD + A +PC
Sbjct: 217 SGVNCELEIDECWSQPCLNGATCQDALGAYFC-DCAPGFLGDHCELNTDECASQPCLHGG 275
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRN 187
C+ Y C SG+ G C + +PC + +C +
Sbjct: 276 LCVDGENR--YSCNCTGSGF--TGTHCETLMPLCWSKPCHNNATCED 318
Score = 42.7 bits (96), Expect = 0.005
Identities = 39/137 (28%), Positives = 51/137 (37%), Gaps = 19/137 (13%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGP 110
C++NPC G C+D+ Y C CP G+ G E C +N C G +C +
Sbjct: 1143 CNSNPCLHGG-NCEDIYSS-YHCS-CPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAAY 1198
Query: 111 KCGSCPTGYVG-----DGRQCQ-HVCDAQKPC-----GRERRCMPKSTSPYYECEGCPS- 158
C +C GY G D CQ H C C G C T + PS
Sbjct: 1199 HC-TCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
Query: 159 --GYQWNGYTCVDMDEC 173
G + TC + C
Sbjct: 1258 VCGNEKTNLTCYNGGNC 1274
Score = 34.3 bits (75), Expect = 1.7
Identities = 35/127 (27%), Positives = 49/127 (38%), Gaps = 15/127 (11%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
C+ C D + C PG + + C ++ C G C +G Y C C
Sbjct: 1186 CIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGAT-CISHTNG-YSC-LCFG 1242
Query: 79 GFHGNGVECYRIS---C---RAN-TCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
F G R+ C + N TC+ G +C E Q KC C G+ G+ C+ D
Sbjct: 1243 NFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKC-MCRPGFTGE--WCEKDID 1299
Query: 132 --AQKPC 136
A PC
Sbjct: 1300 ECASDPC 1306
>AB208923-1|BAD92160.1| 441|Homo sapiens crumbs homolog 1 isoform
II precursor variant protein.
Length = 441
Score = 72.5 bits (170), Expect = 5e-12
Identities = 51/162 (31%), Positives = 64/162 (39%), Gaps = 9/162 (5%)
Query: 28 DQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVEC 87
D C + D + C +NPC G C + P R KCP G+ G E
Sbjct: 76 DNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT-CVNTPGERSFLCKCPPGYSGTICET 134
Query: 88 YRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKST 147
SC N+C G C + P C CP GY G + H A PC C
Sbjct: 135 TIGSCGKNSCQHGGICHQDPIYPVC-ICPAGYAGRFCEIDHDECASSPCQNGAVCQDGID 193
Query: 148 SPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNE 188
Y C C GYQ G C +++DEC PC + +C NE
Sbjct: 194 G--YSC-FCVPGYQ--GRHCDLEVDEC-ASDPCKNEATCLNE 229
Score = 61.7 bits (143), Expect = 1e-08
Identities = 43/155 (27%), Positives = 64/155 (41%), Gaps = 13/155 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D + C+ PG + C++ PC G + C D + RY C SGF
Sbjct: 261 GATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGL-CVD-GENRYSCNCTGSGF 318
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ---HVCDAQKPCG 137
G E C + C +CE++ C C GY G QC+ + C++ PC
Sbjct: 319 TGTHCETLMPLCWSKPCHNNATCEDSVDNYTC-HCWPGYT--GAQCEIDLNECNS-NPCQ 374
Query: 138 RERRCMPKSTSPYY-ECEGCPSGYQW---NGYTCV 168
C+ S+ Y G PS + + +GY C+
Sbjct: 375 SNGECVELSSEKQYGRITGLPSSFSYHEASGYVCI 409
Score = 55.6 bits (128), Expect = 7e-07
Identities = 41/167 (24%), Positives = 63/167 (37%), Gaps = 8/167 (4%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D G+ C PG Q C+++PC ++ GRY C CP +
Sbjct: 185 GAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEI--GRYTC-ICPHNY 241
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
G E C + C G +C++ C C G++GD + A +PC
Sbjct: 242 SGVNCELEIDECWSQPCLNGATCQDALGAYFC-DCAPGFLGDHCELNTDECASQPCLHGG 300
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRN 187
C+ Y C SG+ G C + +PC + +C +
Sbjct: 301 LCVDGENR--YSCNCTGSGF--TGTHCETLMPLCWSKPCHNNATCED 343
>X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein.
Length = 1184
Score = 71.7 bits (168), Expect = 9e-12
Identities = 77/240 (32%), Positives = 106/240 (44%), Gaps = 39/240 (16%)
Query: 21 GERCVDTDQGFRCERCP-----GSQTSD-GQTC----RTACSANPCFGGRVPCQDLPDGR 70
G C++T + C+R P G SD G C + C G+V C +LP G
Sbjct: 824 GFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQV-CHNLP-GS 881
Query: 71 YQCGKCPSGFHGN--GVECYRIS-CRANTC-FQGVSCEETQYGPKCGSCPTGYV--GDGR 124
Y+C C +GF + G C ++ C A+ +CE T +C SC +G++ DG+
Sbjct: 882 YRCD-CKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRC-SCASGFLLAADGK 939
Query: 125 QCQHV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCD 180
+C+ V C+AQ+ C +E C S Y+C C GYQ +G+TC D+DEC
Sbjct: 940 RCEDVNECEAQR-CSQE--CANIYGS--YQCY-CRQGYQLAEDGHTCTDIDECAQGAGIL 993
Query: 181 DLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVN 240
C N QG+ T N R C DVDECA G NC C N
Sbjct: 994 CTFRCLNVPGSYQCACP------EQGYTMTANGRS---CKDVDECALGTHNCSEAETCHN 1044
Score = 47.6 bits (108), Expect = 2e-04
Identities = 47/172 (27%), Positives = 69/172 (40%), Gaps = 17/172 (9%)
Query: 83 NGVECYRIS-CRAN--TCFQGVSCEETQYGPKCG---SCPTGYVGDGRQCQHVCDAQK-- 134
+GV C I+ C + TC +G C T C +C GY +C+ V +
Sbjct: 713 DGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGT 772
Query: 135 -PCGRERRCMPKSTSPYYEC-EGCPSGY-QWNGYTCVDMDEC-DLIRPCDDLVSCRNEEX 190
C C S Y + + C G+ Q CVD++EC L PC SC N
Sbjct: 773 HTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCIN--T 830
Query: 191 XXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
++G+ + + + CVDV+EC G C G++C N P
Sbjct: 831 VGSYTCQRNPLICARGYHASDDGAK---CVDVNECETGVHRCGEGQVCHNLP 879
Score = 36.7 bits (81), Expect = 0.33
Identities = 35/114 (30%), Positives = 44/114 (38%), Gaps = 18/114 (15%)
Query: 219 CVDVDECADGRANCPRGRLCVNTP-QYPSNPVSSLQGSYICVPCGGHYYVN----TTRPC 273
C DVDECA G C G LC NT + ++ P G +N + PC
Sbjct: 762 CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPC 821
Query: 274 FDPDSLVKRCDPSYCRRFNAVC--GF-----GQKCV----CNTG--WTGNGTVC 314
S + C+R +C G+ G KCV C TG G G VC
Sbjct: 822 RPGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVC 875
>BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein.
Length = 1184
Score = 71.7 bits (168), Expect = 9e-12
Identities = 77/240 (32%), Positives = 106/240 (44%), Gaps = 39/240 (16%)
Query: 21 GERCVDTDQGFRCERCP-----GSQTSD-GQTC----RTACSANPCFGGRVPCQDLPDGR 70
G C++T + C+R P G SD G C + C G+V C +LP G
Sbjct: 824 GFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQV-CHNLP-GS 881
Query: 71 YQCGKCPSGFHGN--GVECYRIS-CRANTC-FQGVSCEETQYGPKCGSCPTGYV--GDGR 124
Y+C C +GF + G C ++ C A+ +CE T +C SC +G++ DG+
Sbjct: 882 YRCD-CKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRC-SCASGFLLAADGK 939
Query: 125 QCQHV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCD 180
+C+ V C+AQ+ C +E C S Y+C C GYQ +G+TC D+DEC
Sbjct: 940 RCEDVNECEAQR-CSQE--CANIYGS--YQCY-CRQGYQLAEDGHTCTDIDECAQGAGIL 993
Query: 181 DLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVN 240
C N QG+ T N R C DVDECA G NC C N
Sbjct: 994 CTFRCLNVPGSYQCACP------EQGYTMTANGRS---CKDVDECALGTHNCSEAETCHN 1044
Score = 47.6 bits (108), Expect = 2e-04
Identities = 47/172 (27%), Positives = 69/172 (40%), Gaps = 17/172 (9%)
Query: 83 NGVECYRIS-CRAN--TCFQGVSCEETQYGPKCG---SCPTGYVGDGRQCQHVCDAQK-- 134
+GV C I+ C + TC +G C T C +C GY +C+ V +
Sbjct: 713 DGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGT 772
Query: 135 -PCGRERRCMPKSTSPYYEC-EGCPSGY-QWNGYTCVDMDEC-DLIRPCDDLVSCRNEEX 190
C C S Y + + C G+ Q CVD++EC L PC SC N
Sbjct: 773 HTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCIN--T 830
Query: 191 XXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
++G+ + + + CVDV+EC G C G++C N P
Sbjct: 831 VGSYTCQRNPLICARGYHASDDGAK---CVDVNECETGVHRCGEGQVCHNLP 879
Score = 36.7 bits (81), Expect = 0.33
Identities = 35/114 (30%), Positives = 44/114 (38%), Gaps = 18/114 (15%)
Query: 219 CVDVDECADGRANCPRGRLCVNTP-QYPSNPVSSLQGSYICVPCGGHYYVN----TTRPC 273
C DVDECA G C G LC NT + ++ P G +N + PC
Sbjct: 762 CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPC 821
Query: 274 FDPDSLVKRCDPSYCRRFNAVC--GF-----GQKCV----CNTG--WTGNGTVC 314
S + C+R +C G+ G KCV C TG G G VC
Sbjct: 822 RPGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVC 875
>AY130459-1|AAN05436.1| 1231|Homo sapiens fibulin 2 protein.
Length = 1231
Score = 71.7 bits (168), Expect = 9e-12
Identities = 77/240 (32%), Positives = 106/240 (44%), Gaps = 39/240 (16%)
Query: 21 GERCVDTDQGFRCERCP-----GSQTSD-GQTC----RTACSANPCFGGRVPCQDLPDGR 70
G C++T + C+R P G SD G C + C G+V C +LP G
Sbjct: 871 GFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQV-CHNLP-GS 928
Query: 71 YQCGKCPSGFHGN--GVECYRIS-CRANTC-FQGVSCEETQYGPKCGSCPTGYV--GDGR 124
Y+C C +GF + G C ++ C A+ +CE T +C SC +G++ DG+
Sbjct: 929 YRCD-CKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRC-SCASGFLLAADGK 986
Query: 125 QCQHV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCD 180
+C+ V C+AQ+ C +E C S Y+C C GYQ +G+TC D+DEC
Sbjct: 987 RCEDVNECEAQR-CSQE--CANIYGS--YQCY-CRQGYQLAEDGHTCTDIDECAQGAGIL 1040
Query: 181 DLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVN 240
C N QG+ T N R C DVDECA G NC C N
Sbjct: 1041 CTFRCLNVPGSYQCACP------EQGYTMTANGRS---CKDVDECALGTHNCSEAETCHN 1091
Score = 48.4 bits (110), Expect = 1e-04
Identities = 88/334 (26%), Positives = 116/334 (34%), Gaps = 51/334 (15%)
Query: 12 MVTPFKLCVGERCVDTDQGFRCERCPG-SQTSDGQTCRTACSANPCFGGRVPCQDLPDGR 70
++ P +LC C++T + C PG S DG+TCR G P + P
Sbjct: 609 LLLPGELCQ-HLCINTVGSYHCACFPGFSLQDDGRTCRPE--------GHPPQPEAP--- 656
Query: 71 YQCGKCPSGFHGNGVECYRISC-RANTCFQGVSCEE---TQYGPKCGSCPTGY--VGDGR 124
Q S F + + NTC C++ T G SC GY + DG
Sbjct: 657 -QEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGV 715
Query: 125 QC--QHVC-DAQKPCGRERRCMPKSTSPYYECEG--CPSGYQWNGYT-CVDMDECDLIRP 178
C Q C C R + C+ S Y C GY N + CV +EC
Sbjct: 716 SCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVGKNEC----- 770
Query: 179 CDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLC 238
DL +C E G + C DVDECA G C G LC
Sbjct: 771 VTDLHTCSRGEHCVNTLGSFHCYKALTC--EPGYALKDGECEDVDECAMGTHTCQPGFLC 828
Query: 239 VNTP-QYPSNPVSSLQGSYICVPCGGHYYVN----TTRPCFDPDSLVKRCDPSYCRRFNA 293
NT + ++ P G +N + PC S + C+R
Sbjct: 829 QNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPL 888
Query: 294 VC--GF-----GQKCV----CNTG--WTGNGTVC 314
+C G+ G KCV C TG G G VC
Sbjct: 889 ICARGYHASDDGAKCVDVNECETGVHRCGEGQVC 922
Score = 46.4 bits (105), Expect = 4e-04
Identities = 42/157 (26%), Positives = 62/157 (39%), Gaps = 14/157 (8%)
Query: 95 NTCFQGVSCEETQYGPKCG---SCPTGYVGDGRQCQHVCDAQK---PCGRERRCMPKSTS 148
+TC +G C T C +C GY +C+ V + C C S
Sbjct: 775 HTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGS 834
Query: 149 PYYEC-EGCPSGY-QWNGYTCVDMDEC-DLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQ 205
Y + + C G+ Q CVD++EC L PC SC N ++
Sbjct: 835 FYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCIN--TVGSYTCQRNPLICAR 892
Query: 206 GWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G+ + + + CVDV+EC G C G++C N P
Sbjct: 893 GYHASDDGAK---CVDVNECETGVHRCGEGQVCHNLP 926
>AY130458-1|AAN05435.1| 1231|Homo sapiens fibulin 2 protein.
Length = 1231
Score = 71.7 bits (168), Expect = 9e-12
Identities = 77/240 (32%), Positives = 106/240 (44%), Gaps = 39/240 (16%)
Query: 21 GERCVDTDQGFRCERCP-----GSQTSD-GQTC----RTACSANPCFGGRVPCQDLPDGR 70
G C++T + C+R P G SD G C + C G+V C +LP G
Sbjct: 871 GFSCINTVGSYTCQRNPLICARGYHASDDGXKCVDVNECETGVHRCGEGQV-CHNLP-GS 928
Query: 71 YQCGKCPSGFHGN--GVECYRIS-CRANTC-FQGVSCEETQYGPKCGSCPTGYV--GDGR 124
Y+C C +GF + G C ++ C A+ +CE T +C SC +G++ DG+
Sbjct: 929 YRCD-CKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRC-SCASGFLLAADGK 986
Query: 125 QCQHV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCD 180
+C+ V C+AQ+ C +E C S Y+C C GYQ +G+TC D+DEC
Sbjct: 987 RCEDVNECEAQR-CSQE--CANIYGS--YQCY-CRQGYQLAEDGHTCTDIDECAQGAGIL 1040
Query: 181 DLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVN 240
C N QG+ T N R C DVDECA G NC C N
Sbjct: 1041 CTFRCLNVPGSYQCACP------EQGYTMTANGRS---CKDVDECALGTHNCSEAETCHN 1091
Score = 52.0 bits (119), Expect = 8e-06
Identities = 89/334 (26%), Positives = 118/334 (35%), Gaps = 51/334 (15%)
Query: 12 MVTPFKLCVGERCVDTDQGFRCERCPG-SQTSDGQTCRTACSANPCFGGRVPCQDLPDGR 70
++ P +LC C++T + C PG S DG+TCR G P + P
Sbjct: 609 LLLPGELCQ-HLCINTVGSYHCACFPGFSLQDDGRTCRPE--------GHPPQPEAP--- 656
Query: 71 YQCGKCPSGFHGNGVECYRISC-RANTCFQGVSCEE---TQYGPKCGSCPTGY--VGDGR 124
Q S F + + NTC C++ T G SC GY + DG
Sbjct: 657 -QEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGV 715
Query: 125 QC--QHVC-DAQKPCGRERRCMPKSTSPYYECEG--CPSGYQWNGYT-CVDMDECDLIRP 178
C Q C C R + C+ S Y C GY N + CVD++EC
Sbjct: 716 SCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINEC----- 770
Query: 179 CDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLC 238
DL +C E G + C DVDECA G C G LC
Sbjct: 771 VTDLHTCSRGEHCVNTLGSFHCYKALTC--EPGYALKDGECEDVDECAMGTHTCQPGFLC 828
Query: 239 VNTP-QYPSNPVSSLQGSYICVPCGGHYYVN----TTRPCFDPDSLVKRCDPSYCRRFNA 293
NT + ++ P G +N + PC S + C+R
Sbjct: 829 QNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPL 888
Query: 294 VC--GF-----GQKCV----CNTG--WTGNGTVC 314
+C G+ G KCV C TG G G VC
Sbjct: 889 ICARGYHASDDGXKCVDVNECETGVHRCGEGQVC 922
Score = 46.4 bits (105), Expect = 4e-04
Identities = 42/157 (26%), Positives = 62/157 (39%), Gaps = 14/157 (8%)
Query: 95 NTCFQGVSCEETQYGPKCG---SCPTGYVGDGRQCQHVCDAQK---PCGRERRCMPKSTS 148
+TC +G C T C +C GY +C+ V + C C S
Sbjct: 775 HTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGS 834
Query: 149 PYYEC-EGCPSGY-QWNGYTCVDMDEC-DLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQ 205
Y + + C G+ Q CVD++EC L PC SC N ++
Sbjct: 835 FYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCIN--TVGSYTCQRNPLICAR 892
Query: 206 GWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G+ + + + CVDV+EC G C G++C N P
Sbjct: 893 GYHASDDGXK---CVDVNECETGVHRCGEGQVCHNLP 926
>AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 3 protein.
Length = 2809
Score = 70.9 bits (166), Expect = 2e-11
Identities = 92/318 (28%), Positives = 123/318 (38%), Gaps = 50/318 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQ-TSDGQTCR--TACSANPCFGGRVPCQDLPDGRYQCG 74
LC G C +TD ++C+ PG + T+ G C CS + C ++ G +QC
Sbjct: 1081 LCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNV-IGAFQC- 1138
Query: 75 KCPSGFHG--NGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQHV 129
C +GF + C I+ CR V C T+ +C SC GY + DGR C V
Sbjct: 1139 SCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRC-SCGQGYSLMPDGRACADV 1197
Query: 130 --CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSC 185
C+ + C + + C C G+ + TCVD+DECDL C
Sbjct: 1198 DECEENPRVCDQGHC--TNMPGGHRCL-CYDGFMATPDMRTCVDVDECDLNPHICLHGDC 1254
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N + +G G C DVDEC G NC C+N P
Sbjct: 1255 ENTK-GSFVCHCQLGYMVRKGATG---------CSDVDECEVGGHNCDSHASCLNIP--- 1301
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK---RCDP-SYCRRFNAVCGFGQKC 301
GS+ C G +V C D D V RC P C V G +C
Sbjct: 1302 --------GSFSCRCLPG--WVGDGFECHDLDECVSQEHRCSPRGDCLN---VPG-SYRC 1347
Query: 302 VCNTGWTGNGTVCGLDRD 319
C G+ G+G C DRD
Sbjct: 1348 TCRQGFAGDGFFCE-DRD 1364
Score = 62.9 bits (146), Expect = 4e-09
Identities = 92/315 (29%), Positives = 117/315 (37%), Gaps = 53/315 (16%)
Query: 21 GERCVDTDQGF---RCE--RCPGSQTSDGQTCRTACSANPCFGGRVPCQDLP-DGRYQCG 74
G RC DT Q F R E +C + + R CS P G PC+ P +G
Sbjct: 2006 GHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQ 2065
Query: 75 K-CPSGFHGN--GVECYRIS---CRAN--TCFQGVSCEETQYGPKCGSCPTGYVGD--GR 124
+ CP G HG G + R C N C GV C T +C CP GY D G
Sbjct: 2066 ELCPFG-HGAVPGPDDSREDVNECAENPGVCTNGV-CVNTDGSFRC-ECPFGYSLDFTGI 2122
Query: 125 QCQHV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN-GYTCVDMDECDLIRPCDD 181
C C PCG + C + +EC C G++ TC D+DEC L P
Sbjct: 2123 NCVDTDECSVGHPCG-QGTCT--NVIGGFEC-ACADGFEPGLMMTCEDIDECSL-NPLLC 2177
Query: 182 LVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC-PRGRLCVN 240
C N E G C DVDECADG+ +C RG C N
Sbjct: 2178 AFRCHNTEGSYLCTCPAGYTLREDG----------AMCRDVDECADGQQDCHARGMECKN 2227
Query: 241 TPQYPSNPVSSLQGSYICV-PCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ 299
L G++ CV P G + C D + P C V G
Sbjct: 2228 -----------LIGTFACVCPPGMRPLPGSGEGCTDDNEC--HAQPDLCVNGRCVNTAGS 2274
Query: 300 -KCVCNTGWTGNGTV 313
+C C+ G+ + T+
Sbjct: 2275 FRCDCDEGFQPSPTL 2289
Score = 61.3 bits (142), Expect = 1e-08
Identities = 64/231 (27%), Positives = 85/231 (36%), Gaps = 33/231 (14%)
Query: 24 CVDTDQGFRCERCPGSQT--SDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCGKCPS 78
C +T F C CP DG+TC+ + C + CQ L G + C +CP
Sbjct: 2420 CKNTKGSFLCS-CPRGYLLEEDGRTCK---DLDECTSRQHNCQFLCVNTVGAFTC-RCPP 2474
Query: 79 GFHGNGVECY---RISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQHVCDAQ 133
GF + C+ S + C C T +C C G+ V G C+ V +
Sbjct: 2475 GFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRC-ECHQGFTLVSSGHGCEDVNECD 2533
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGY--TCVDMDECDLIRPCDDLVSCRNEEXX 191
P + C + Y C CP G+ + CVD +EC L P SCRN
Sbjct: 2534 GPHRCQHGCQNQLGG--YRCS-CPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGG 2590
Query: 192 XXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G ++ C DVDECA R C C NTP
Sbjct: 2591 FRCVCPS----------GFDFDQALGGCQDVDECAGRRGPCSYS--CANTP 2629
Score = 57.6 bits (133), Expect = 2e-07
Identities = 79/293 (26%), Positives = 107/293 (36%), Gaps = 51/293 (17%)
Query: 17 KLCVGERCVDTDQGFRCERCPGSQ-TSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQC 73
++C C + G RC G T D +TC C NP C++ G + C
Sbjct: 1205 RVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTK-GSFVC 1263
Query: 74 GKCPSGF--HGNGVECYRIS-CRA--NTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQH 128
C G+ C + C + C SC C C G+VGDG +C
Sbjct: 1264 -HCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSC-RCLPGWVGDGFECH- 1320
Query: 129 VCDAQKPCGRERRCMPK----STSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDLV 183
D + +E RC P+ + Y C C G+ +G+ C D DEC + + CD+
Sbjct: 1321 --DLDECVSQEHRCSPRGDCLNVPGSYRCT-CRQGFAGDGFFCEDRDECAENVDLCDN-G 1376
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQ 243
C N G+ T + R C DVDECA G C G C N P
Sbjct: 1377 QCLN-------APGGYRCECEMGFDPTEDHRA---CQDVDECAQGNL-CAFGS-CENLP- 1423
Query: 244 YPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRC-DPSYCRRFNAVC 295
G + C+ GG+ C D + C DP C N VC
Sbjct: 1424 ----------GMFRCICNGGYELDRGGGNCTD----INECADPVNC--INGVC 1460
Score = 55.6 bits (128), Expect = 7e-07
Identities = 66/239 (27%), Positives = 94/239 (39%), Gaps = 36/239 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACS-ANPC-FGGR-----VPCQDLPDGR 70
+C+ C +T F C G G T CS + C GG C ++P G
Sbjct: 1248 ICLHGDCENTKGSFVCHCQLGYMVRKGAT---GCSDVDECEVGGHNCDSHASCLNIP-GS 1303
Query: 71 YQCGKCPSGFHGNGVECYRIS-C--RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ 127
+ C +C G+ G+G EC+ + C + + C C +C +C G+ GDG C+
Sbjct: 1304 FSC-RCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRC-TCRQGFAGDGFFCE 1361
Query: 128 H--VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLV 183
C +C+ + Y CE C G+ + C D+DEC C
Sbjct: 1362 DRDECAENVDLCDNGQCL--NAPGGYRCE-CEMGFDPTEDHRACQDVDECAQGNLCA-FG 1417
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
SC N RG GN C D++ECAD NC G +C+NTP
Sbjct: 1418 SCENLPGMFRCICNGGYELD----RGGGN------CTDINECAD-PVNCING-VCINTP 1464
Score = 55.2 bits (127), Expect = 9e-07
Identities = 88/361 (24%), Positives = 128/361 (35%), Gaps = 51/361 (14%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQ----TCRTACSANPCFGGRVPCQDLPDGRYQC 73
LC C +T F C C G D Q T C +P G+ C + P G ++C
Sbjct: 996 LCTHGTCRNTVGSFHCA-CAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTP-GSFEC 1053
Query: 74 GKCPSGFHGNGV---ECYRIS--CRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQC 126
+C G+ + C + R +G +C T KC CP G+ G C
Sbjct: 1054 -ECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKC-QCPPGHELTAKGTAC 1111
Query: 127 QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRP-CDDLV 183
+ + + G + ++C C +G+Q + CVD++EC + CD V
Sbjct: 1112 EDIDECSLSDGLCPHGQCVNVIGAFQCS-CHAGFQSTPDRQGCVDINECRVQNGGCD--V 1168
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRRE--------HCVDVDE-----CADGRA 230
C N E G + E HC ++ C DG
Sbjct: 1169 HCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFM 1228
Query: 231 NCPRGRLCVNTPQYPSNP-------VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLV--- 280
P R CV+ + NP + +GS++C G+ C D D
Sbjct: 1229 ATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGG 1288
Query: 281 KRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRCKKDNC 340
CD S+ N F C C GW G+G C DLD ++ C+ PR N
Sbjct: 1289 HNCD-SHASCLNIPGSF--SCRCLPGWVGDGFEC---HDLDECVSQEHRCS-PRGDCLNV 1341
Query: 341 P 341
P
Sbjct: 1342 P 1342
Score = 54.8 bits (126), Expect = 1e-06
Identities = 77/300 (25%), Positives = 107/300 (35%), Gaps = 51/300 (17%)
Query: 24 CVDTDQGFRCERCPG-SQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C++T+ +RC G S DG+ C C NP + C ++P G ++C C GF
Sbjct: 1170 CINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGG-HRC-LCYDGF 1227
Query: 81 HGNG-----VECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY-VGDGRQ-CQHVCDAQ 133
V+ + C G CE T+ C C GY V G C V + +
Sbjct: 1228 MATPDMRTCVDVDECDLNPHICLHG-DCENTKGSFVC-HCQLGYMVRKGATGCSDVDECE 1285
Query: 134 ---KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDLVSCRNEE 189
C C+ S + C C G+ +G+ C D+DEC C C N
Sbjct: 1286 VGGHNCDSHASCLNIPGS--FSCR-CLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVP 1342
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPV 249
QG+ G G C D DECA+ C G+ C+N P
Sbjct: 1343 GSYRCTCR-------QGFAGDGF-----FCEDRDECAENVDLCDNGQ-CLNAP------- 1382
Query: 250 SSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK--RCDPSYCRRFNAVCGFGQKCVCNTGW 307
G Y C G R C D D + C C + +C+CN G+
Sbjct: 1383 ----GGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMF----RCICNGGY 1434
Score = 54.8 bits (126), Expect = 1e-06
Identities = 90/342 (26%), Positives = 126/342 (36%), Gaps = 67/342 (19%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGG--RVPCQDLPDG-----R 70
LCV RCV+T FRC+ G Q S T PCF + C+ L R
Sbjct: 2262 LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTR 2321
Query: 71 YQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCP--TGYVGDGRQCQH 128
+C C G G G C + ++ + CP +GY +GR
Sbjct: 2322 AEC--CCGGGRGWGPRCELCPLPGTSAYRKL-------------CPHGSGYTAEGRDVDE 2366
Query: 129 VCDAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLI-RPCDDLVSC 185
C C+ S + C C +GY TC+DMDEC + +PC L C
Sbjct: 2367 -CRMLAHLCAHGECINSLGS--FRCH-CQAGYTPDATATTCLDMDECSQVPKPCTFL--C 2420
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
+N + RG E C D+DEC + NC LCVNT
Sbjct: 2421 KNTKGSFLCSCP----------RGYLLEEDGRTCKDLDECTSRQHNCQ--FLCVNT---- 2464
Query: 246 SNPVSSLQGSYIC-VPCGGHYYVNTTRPCFDPDSLVKRCDP--SYCRRFNAVCGFGQKCV 302
G++ C P G + + CFD D + P ++ N F +C
Sbjct: 2465 -------VGAFTCRCPPG---FTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSF--RCE 2512
Query: 303 CNTGWT--GNGTVCGLDRDLDGHPDEQLPC-NEPRCKKDNCP 341
C+ G+T +G C + DG Q C N+ + +CP
Sbjct: 2513 CHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCP 2554
Score = 48.4 bits (110), Expect = 1e-04
Identities = 56/229 (24%), Positives = 87/229 (37%), Gaps = 29/229 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTC--RTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
C++ +RC+ G + S G C R C P C D +G Y C C GF
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMD-TEGSYMC-LCHRGFQ 1837
Query: 82 GNGVE--CYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGR 138
+ + C I C C G +C+ C P V C + G+
Sbjct: 1838 ASADQTLCMDIDECDRQPCGNG-TCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1896
Query: 139 ERR---CMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSCRNEEXXXX 193
R C+ +T+ + C C G++ +G CVD +EC + +C+N E
Sbjct: 1897 VCRFGHCL--NTAGSFHCL-CQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFR 1953
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G + + +HC+D+DEC++ C G C N+P
Sbjct: 1954 CIC------------PPGFQVQSDHCIDIDECSEEPNLCLFG-TCTNSP 1989
Score = 48.0 bits (109), Expect = 1e-04
Identities = 53/186 (28%), Positives = 77/186 (41%), Gaps = 26/186 (13%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSD--GQTCRT-ACSANPCFGGRVPCQDLPDGRYQCG 74
LC+ RC+ T +RCE C T D G+ C+++PC G C ++P G Y C
Sbjct: 418 LCLNGRCLPTPSSYRCE-CNVGYTQDVRGECIDVDECTSSPCHHG--DCVNIP-GTYHC- 472
Query: 75 KCPSGFHGNGVE--CYRI-SC--RANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQC- 126
+C GF C + C C G C T+ +C C G+ DG+ C
Sbjct: 473 RCYPGFQATPTRQACVDVDECIVSGGLCHLG-RCVNTEGSFQC-VCNAGFELSPDGKNCV 530
Query: 127 -QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLV 183
+ C C C+ + S + C C G+ G+ C+D+DEC C +
Sbjct: 531 DHNECATSTMC-VNGVCLNEDGS--FSCL-CKPGFLLAPGGHYCMDIDECQTPGICVN-G 585
Query: 184 SCRNEE 189
C N E
Sbjct: 586 HCTNTE 591
Score = 47.2 bits (107), Expect = 2e-04
Identities = 85/324 (26%), Positives = 113/324 (34%), Gaps = 57/324 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKC- 76
LC+ C ++ F+C PG SD + + CF R Q R++ GKC
Sbjct: 1979 LCLFGTCTNSPGSFQCLCPPGFVLSD--------NGHRCFDTR---QSFCFTRFEAGKCS 2027
Query: 77 -PSGFHGNGVECYRISCRANTCFQGVSCEET-QYGPKCGS--CPTGYVG-----DGRQCQ 127
P F+ C S R + G CE Q G CP G+ D R+
Sbjct: 2028 VPKAFNTTKTRCC-CSKRPGEGW-GDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDV 2085
Query: 128 HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLVSC 185
+ C A+ P G + +T + CE CP GY + G CVD DEC + PC +C
Sbjct: 2086 NEC-AENP-GVCTNGVCVNTDGSFRCE-CPFGYSLDFTGINCVDTDECSVGHPCGQ-GTC 2141
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N G T C D+DEC+ C C NT
Sbjct: 2142 TN---VIGGFECACADGFEPGLMMT--------CEDIDECSLNPLLC--AFRCHNT---- 2184
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCN 304
+GSY+C G+ C D D + R G CVC
Sbjct: 2185 -------EGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCP 2237
Query: 305 TGW---TGNGTVCGLDRDLDGHPD 325
G G+G C D + PD
Sbjct: 2238 PGMRPLPGSGEGCTDDNECHAQPD 2261
Score = 44.4 bits (100), Expect = 0.002
Identities = 45/168 (26%), Positives = 67/168 (39%), Gaps = 21/168 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQT-CRTA--CSANPCFGGRVPCQDLPDGRYQCG 74
+C C+DT+ + C G Q S QT C C PC G C+++ G Y C
Sbjct: 1815 VCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGT--CKNII-GSYNC- 1870
Query: 75 KCPSGF----HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQH 128
C GF +G+ V+ + + C T C C G+ DG+ C
Sbjct: 1871 LCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHC-LCQDGFELTADGKNCVD 1929
Query: 129 VCDAQKPCGRERRCMP---KSTSPYYECEGCPSGYQWNGYTCVDMDEC 173
+ G C+P ++ + C CP G+Q C+D+DEC
Sbjct: 1930 TNECLSLAGT---CLPGTCQNLEGSFRCI-CPPGFQVQSDHCIDIDEC 1973
Score = 43.6 bits (98), Expect = 0.003
Identities = 66/259 (25%), Positives = 96/259 (37%), Gaps = 46/259 (17%)
Query: 69 GRYQCGKCPSGFHGNGV--ECYRIS-C--RANTCFQGVSCEETQYGPKCGSCPTGY-VGD 122
G ++C +CP+GF+ N + C + C R + C Q C +C C GY +
Sbjct: 1742 GSFRC-ECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC-KCTRGYKLSP 1799
Query: 123 GRQC--QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLIRP 178
G C ++ C CM T Y C C G+Q + C+D+DECD +P
Sbjct: 1800 GGACVGRNECREIPNVCSHGDCM--DTEGSYMCL-CHRGFQASADQTLCMDIDECDR-QP 1855
Query: 179 CDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLC 238
C + +C+N G+ T N CVD DEC R C
Sbjct: 1856 CGN-GTCKN-------IIGSYNCLCFPGFVVTHN----GDCVDFDECTTLVGQVCRFGHC 1903
Query: 239 VNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPD---SLVKRCDPSYCRRFNAVC 295
+NT GS+ C+ G + C D + SL C P C+
Sbjct: 1904 LNT-----------AGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEG-- 1950
Query: 296 GFGQKCVCNTGWTGNGTVC 314
+C+C G+ C
Sbjct: 1951 --SFRCICPPGFQVQSDHC 1967
Score = 42.7 bits (96), Expect = 0.005
Identities = 84/334 (25%), Positives = 122/334 (36%), Gaps = 59/334 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDG-QTCRTA--CSANPCFGGRVPCQDLPDGRYQCG 74
LC G CV+T F+CE PG S+ + C CS + G C + G Y C
Sbjct: 1573 LCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTL-GNYTC- 1630
Query: 75 KCPSGFH--GNGVECYRISCRANTCFQ---GVSCEETQYGPKCGSCPTGYVGDGRQCQHV 129
CP+ + G C + R + CF+ G E + C Y G+
Sbjct: 1631 VCPAEYLQVNGGNNC--MDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSY-NIGQAWNRP 1687
Query: 130 CDAQKPCGRERRCMPKSTSPYYE--CEGCPSGYQWNGYTC--VDMDECDLIRPCDDLVSC 185
C+A C P SP Y+ C G+ + +T +D+DEC I C
Sbjct: 1688 CEA---------C-PTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANGIC 1737
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N+ + G C DVDEC + C + C+N P
Sbjct: 1738 INQ----------IGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIP--- 1784
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCN 304
GSY C C Y ++ C + R P+ C + + G C+C+
Sbjct: 1785 --------GSYRC-KCTRGYKLSPGGACVGRNEC--REIPNVCSHGDCMDTEGSYMCLCH 1833
Query: 305 TGW--TGNGTVCGLDRDLDGHPDEQLPCNEPRCK 336
G+ + + T+C D+D D Q PC CK
Sbjct: 1834 RGFQASADQTLC---MDID-ECDRQ-PCGNGTCK 1862
Score = 39.5 bits (88), Expect = 0.046
Identities = 54/216 (25%), Positives = 80/216 (37%), Gaps = 34/216 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPG-SQTSDGQTCRTACSANPCFGG--RVPC-QDLPD--GRY 71
+CV C +T+ FRC+ G + +DG+ C + C+G + C + P +
Sbjct: 581 ICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKS 640
Query: 72 QCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
+C C + HG G C + + FQ + C S G DGR
Sbjct: 641 EC-CCANPDHGFGEPCQLCPAKNSAEFQAL----------CSS-GLGITTDGRDINECAL 688
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLVSCRNEE 189
+ C + ++ Y C C GY+ +G C D+DEC L D C+N
Sbjct: 689 DPEVCANG---VCENLRGSYRCV-CNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSP 744
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDEC 225
W+ T E C DVDEC
Sbjct: 745 GSYSCSCPPGFHF----WQDT------EICKDVDEC 770
Score = 37.5 bits (83), Expect = 0.19
Identities = 86/345 (24%), Positives = 114/345 (33%), Gaps = 67/345 (19%)
Query: 8 DAGSMVTPFKLCVGERCVDTDQGFRCERCPGSQTS-DGQTC--------RTACSANPCFG 58
D + LC RCV+T+ F+C G + S DG+ C T C C
Sbjct: 489 DVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLN 548
Query: 59 --GRVPCQD------LPDGRY-----QC---GKCPSGFHGNGVECYRISCRANTCF--QG 100
G C P G Y +C G C +G N +R C G
Sbjct: 549 EDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDG 608
Query: 101 VSCEETQYGPKC------GSCPTGYVGDGRQCQHVC-DAQKPCGRERRCMPKSTSPYYEC 153
C +T C GSC + G + + C + G + P S ++
Sbjct: 609 RVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQA 668
Query: 154 EGCPSGYQWNGYTCV--DMDECDLI-RPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGT 210
C SG G T D++EC L C + V C N + G
Sbjct: 669 L-CSSGL---GITTDGRDINECALDPEVCANGV-CENLRGSYRCVCNLGYEAGASG---- 719
Query: 211 GNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTT 270
+ C DVDECA C G C N+P GSY C G ++ T
Sbjct: 720 ------KDCTDVDECALNSLLCDNG-WCQNSP-----------GSYSCSCPPGFHFWQDT 761
Query: 271 RPCFDPDS-LVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
C D D L C CR N + KC + +GT C
Sbjct: 762 EICKDVDECLSSPCVSGVCR--NLAGSYTCKCGPGSRLDPSGTFC 804
Score = 35.5 bits (78), Expect = 0.75
Identities = 35/110 (31%), Positives = 50/110 (45%), Gaps = 14/110 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPG-SQTSDGQTCRTA--CS-ANPCFGGRVPCQDLPDGRYQC 73
LC +C++ G+RCE G T D + C+ C+ N C G C++LP G ++C
Sbjct: 1372 LCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFG--SCENLP-GMFRC 1428
Query: 74 GKCPSGFH--GNGVECYRISCRAN--TCFQGVSCEETQYGPKCGSCPTGY 119
C G+ G C I+ A+ C GV C T C SCP +
Sbjct: 1429 -ICNGGYELDRGGGNCTDINECADPVNCINGV-CINTPGSYLC-SCPQDF 1475
Score = 33.5 bits (73), Expect = 3.0
Identities = 29/93 (31%), Positives = 36/93 (38%), Gaps = 17/93 (18%)
Query: 216 REHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFD 275
R C+DVDEC + C G CVN P G+Y C G T + C D
Sbjct: 444 RGECIDVDECTS--SPCHHGD-CVNIP-----------GTYHCRCYPGFQATPTRQACVD 489
Query: 276 PDSLVKRCDPSYCRRFNAVCGFGQ-KCVCNTGW 307
D + C V G +CVCN G+
Sbjct: 490 VDECI--VSGGLCHLGRCVNTEGSFQCVCNAGF 520
Score = 31.9 bits (69), Expect = 9.2
Identities = 26/81 (32%), Positives = 31/81 (38%), Gaps = 8/81 (9%)
Query: 1 MHAGSMGDAGSMVTPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPC--- 56
+H G+ D LC G CV+ F C RCP G + SD A C
Sbjct: 240 IHTGACQDVDECQAVPGLCQGGSCVNMVGSFHC-RCPVGHRLSDSSAACEDYRAGACFSV 298
Query: 57 -FGGRVPCQDLPDGRYQCGKC 76
FGGR C G Y +C
Sbjct: 299 LFGGR--CAGDLAGHYTRRQC 317
>AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 2 protein.
Length = 2809
Score = 70.9 bits (166), Expect = 2e-11
Identities = 92/318 (28%), Positives = 123/318 (38%), Gaps = 50/318 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQ-TSDGQTCR--TACSANPCFGGRVPCQDLPDGRYQCG 74
LC G C +TD ++C+ PG + T+ G C CS + C ++ G +QC
Sbjct: 1081 LCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNV-IGAFQC- 1138
Query: 75 KCPSGFHG--NGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQHV 129
C +GF + C I+ CR V C T+ +C SC GY + DGR C V
Sbjct: 1139 SCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRC-SCGQGYSLMPDGRACADV 1197
Query: 130 --CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSC 185
C+ + C + + C C G+ + TCVD+DECDL C
Sbjct: 1198 DECEENPRVCDQGHC--TNMPGGHRCL-CYDGFMATPDMRTCVDVDECDLNPHICLHGDC 1254
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N + +G G C DVDEC G NC C+N P
Sbjct: 1255 ENTK-GSFVCHCQLGYMVRKGATG---------CSDVDECEVGGHNCDSHASCLNIP--- 1301
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK---RCDP-SYCRRFNAVCGFGQKC 301
GS+ C G +V C D D V RC P C V G +C
Sbjct: 1302 --------GSFSCRCLPG--WVGDGFECHDLDECVSQEHRCSPRGDCLN---VPG-SYRC 1347
Query: 302 VCNTGWTGNGTVCGLDRD 319
C G+ G+G C DRD
Sbjct: 1348 TCRQGFAGDGFFCE-DRD 1364
Score = 62.9 bits (146), Expect = 4e-09
Identities = 92/315 (29%), Positives = 117/315 (37%), Gaps = 53/315 (16%)
Query: 21 GERCVDTDQGF---RCE--RCPGSQTSDGQTCRTACSANPCFGGRVPCQDLP-DGRYQCG 74
G RC DT Q F R E +C + + R CS P G PC+ P +G
Sbjct: 2006 GHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQ 2065
Query: 75 K-CPSGFHGN--GVECYRIS---CRAN--TCFQGVSCEETQYGPKCGSCPTGYVGD--GR 124
+ CP G HG G + R C N C GV C T +C CP GY D G
Sbjct: 2066 ELCPFG-HGAVPGPDDSREDVNECAENPGVCTNGV-CVNTDGSFRC-ECPFGYSLDFTGI 2122
Query: 125 QCQHV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN-GYTCVDMDECDLIRPCDD 181
C C PCG + C + +EC C G++ TC D+DEC L P
Sbjct: 2123 NCVDTDECSVGHPCG-QGTCT--NVIGGFEC-ACADGFEPGLMMTCEDIDECSL-NPLLC 2177
Query: 182 LVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC-PRGRLCVN 240
C N E G C DVDECADG+ +C RG C N
Sbjct: 2178 AFRCHNTEGSYLCTCPAGYTLREDG----------AMCRDVDECADGQQDCHARGMECKN 2227
Query: 241 TPQYPSNPVSSLQGSYICV-PCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ 299
L G++ CV P G + C D + P C V G
Sbjct: 2228 -----------LIGTFACVCPPGMRPLPGSGEGCTDDNEC--HAQPDLCVNGRCVNTAGS 2274
Query: 300 -KCVCNTGWTGNGTV 313
+C C+ G+ + T+
Sbjct: 2275 FRCDCDEGFQPSPTL 2289
Score = 61.3 bits (142), Expect = 1e-08
Identities = 64/231 (27%), Positives = 85/231 (36%), Gaps = 33/231 (14%)
Query: 24 CVDTDQGFRCERCPGSQT--SDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCGKCPS 78
C +T F C CP DG+TC+ + C + CQ L G + C +CP
Sbjct: 2420 CKNTKGSFLCS-CPRGYLLEEDGRTCK---DLDECTSRQHNCQFLCVNTVGAFTC-RCPP 2474
Query: 79 GFHGNGVECY---RISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQHVCDAQ 133
GF + C+ S + C C T +C C G+ V G C+ V +
Sbjct: 2475 GFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRC-ECHQGFTLVSSGHGCEDVNECD 2533
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGY--TCVDMDECDLIRPCDDLVSCRNEEXX 191
P + C + Y C CP G+ + CVD +EC L P SCRN
Sbjct: 2534 GPHRCQHGCQNQLGG--YRCS-CPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGG 2590
Query: 192 XXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G ++ C DVDECA R C C NTP
Sbjct: 2591 FRCVCPS----------GFDFDQALGGCQDVDECAGRRGPCSYS--CANTP 2629
Score = 57.6 bits (133), Expect = 2e-07
Identities = 79/293 (26%), Positives = 107/293 (36%), Gaps = 51/293 (17%)
Query: 17 KLCVGERCVDTDQGFRCERCPGSQ-TSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQC 73
++C C + G RC G T D +TC C NP C++ G + C
Sbjct: 1205 RVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTK-GSFVC 1263
Query: 74 GKCPSGF--HGNGVECYRIS-CRA--NTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQH 128
C G+ C + C + C SC C C G+VGDG +C
Sbjct: 1264 -HCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSC-RCLPGWVGDGFECH- 1320
Query: 129 VCDAQKPCGRERRCMPK----STSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDLV 183
D + +E RC P+ + Y C C G+ +G+ C D DEC + + CD+
Sbjct: 1321 --DLDECVSQEHRCSPRGDCLNVPGSYRCT-CRQGFAGDGFFCEDRDECAENVDLCDN-G 1376
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQ 243
C N G+ T + R C DVDECA G C G C N P
Sbjct: 1377 QCLN-------APGGYRCECEMGFDPTEDHRA---CQDVDECAQGNL-CAFGS-CENLP- 1423
Query: 244 YPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRC-DPSYCRRFNAVC 295
G + C+ GG+ C D + C DP C N VC
Sbjct: 1424 ----------GMFRCICNGGYELDRGGGNCTD----INECADPVNC--INGVC 1460
Score = 55.6 bits (128), Expect = 7e-07
Identities = 66/239 (27%), Positives = 94/239 (39%), Gaps = 36/239 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACS-ANPC-FGGR-----VPCQDLPDGR 70
+C+ C +T F C G G T CS + C GG C ++P G
Sbjct: 1248 ICLHGDCENTKGSFVCHCQLGYMVRKGAT---GCSDVDECEVGGHNCDSHASCLNIP-GS 1303
Query: 71 YQCGKCPSGFHGNGVECYRIS-C--RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ 127
+ C +C G+ G+G EC+ + C + + C C +C +C G+ GDG C+
Sbjct: 1304 FSC-RCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRC-TCRQGFAGDGFFCE 1361
Query: 128 H--VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLV 183
C +C+ + Y CE C G+ + C D+DEC C
Sbjct: 1362 DRDECAENVDLCDNGQCL--NAPGGYRCE-CEMGFDPTEDHRACQDVDECAQGNLCA-FG 1417
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
SC N RG GN C D++ECAD NC G +C+NTP
Sbjct: 1418 SCENLPGMFRCICNGGYELD----RGGGN------CTDINECAD-PVNCING-VCINTP 1464
Score = 55.2 bits (127), Expect = 9e-07
Identities = 88/361 (24%), Positives = 128/361 (35%), Gaps = 51/361 (14%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQ----TCRTACSANPCFGGRVPCQDLPDGRYQC 73
LC C +T F C C G D Q T C +P G+ C + P G ++C
Sbjct: 996 LCTHGTCRNTVGSFHCA-CAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTP-GSFEC 1053
Query: 74 GKCPSGFHGNGV---ECYRIS--CRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQC 126
+C G+ + C + R +G +C T KC CP G+ G C
Sbjct: 1054 -ECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKC-QCPPGHELTAKGTAC 1111
Query: 127 QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRP-CDDLV 183
+ + + G + ++C C +G+Q + CVD++EC + CD V
Sbjct: 1112 EDIDECSLSDGLCPHGQCVNVIGAFQCS-CHAGFQSTPDRQGCVDINECRVQNGGCD--V 1168
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRRE--------HCVDVDE-----CADGRA 230
C N E G + E HC ++ C DG
Sbjct: 1169 HCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFM 1228
Query: 231 NCPRGRLCVNTPQYPSNP-------VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLV--- 280
P R CV+ + NP + +GS++C G+ C D D
Sbjct: 1229 ATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGG 1288
Query: 281 KRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRCKKDNC 340
CD S+ N F C C GW G+G C DLD ++ C+ PR N
Sbjct: 1289 HNCD-SHASCLNIPGSF--SCRCLPGWVGDGFEC---HDLDECVSQEHRCS-PRGDCLNV 1341
Query: 341 P 341
P
Sbjct: 1342 P 1342
Score = 54.8 bits (126), Expect = 1e-06
Identities = 77/300 (25%), Positives = 107/300 (35%), Gaps = 51/300 (17%)
Query: 24 CVDTDQGFRCERCPG-SQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C++T+ +RC G S DG+ C C NP + C ++P G ++C C GF
Sbjct: 1170 CINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGG-HRC-LCYDGF 1227
Query: 81 HGNG-----VECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY-VGDGRQ-CQHVCDAQ 133
V+ + C G CE T+ C C GY V G C V + +
Sbjct: 1228 MATPDMRTCVDVDECDLNPHICLHG-DCENTKGSFVC-HCQLGYMVRKGATGCSDVDECE 1285
Query: 134 ---KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDLVSCRNEE 189
C C+ S + C C G+ +G+ C D+DEC C C N
Sbjct: 1286 VGGHNCDSHASCLNIPGS--FSCR-CLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVP 1342
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPV 249
QG+ G G C D DECA+ C G+ C+N P
Sbjct: 1343 GSYRCTCR-------QGFAGDGF-----FCEDRDECAENVDLCDNGQ-CLNAP------- 1382
Query: 250 SSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK--RCDPSYCRRFNAVCGFGQKCVCNTGW 307
G Y C G R C D D + C C + +C+CN G+
Sbjct: 1383 ----GGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMF----RCICNGGY 1434
Score = 54.8 bits (126), Expect = 1e-06
Identities = 90/342 (26%), Positives = 126/342 (36%), Gaps = 67/342 (19%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGG--RVPCQDLPDG-----R 70
LCV RCV+T FRC+ G Q S T PCF + C+ L R
Sbjct: 2262 LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTR 2321
Query: 71 YQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCP--TGYVGDGRQCQH 128
+C C G G G C + ++ + CP +GY +GR
Sbjct: 2322 AEC--CCGGGRGWGPRCELCPLPGTSAYRKL-------------CPHGSGYTAEGRDVDE 2366
Query: 129 VCDAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLI-RPCDDLVSC 185
C C+ S + C C +GY TC+DMDEC + +PC L C
Sbjct: 2367 -CRMLAHLCAHGECINSLGS--FRCH-CQAGYTPDATATTCLDMDECSQVPKPCTFL--C 2420
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
+N + RG E C D+DEC + NC LCVNT
Sbjct: 2421 KNTKGSFLCSCP----------RGYLLEEDGRTCKDLDECTSRQHNCQ--FLCVNT---- 2464
Query: 246 SNPVSSLQGSYIC-VPCGGHYYVNTTRPCFDPDSLVKRCDP--SYCRRFNAVCGFGQKCV 302
G++ C P G + + CFD D + P ++ N F +C
Sbjct: 2465 -------VGAFTCRCPPG---FTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSF--RCE 2512
Query: 303 CNTGWT--GNGTVCGLDRDLDGHPDEQLPC-NEPRCKKDNCP 341
C+ G+T +G C + DG Q C N+ + +CP
Sbjct: 2513 CHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCP 2554
Score = 48.4 bits (110), Expect = 1e-04
Identities = 56/229 (24%), Positives = 87/229 (37%), Gaps = 29/229 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTC--RTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
C++ +RC+ G + S G C R C P C D +G Y C C GF
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMD-TEGSYMC-LCHRGFQ 1837
Query: 82 GNGVE--CYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGR 138
+ + C I C C G +C+ C P V C + G+
Sbjct: 1838 ASADQTLCMDIDECDRQPCGNG-TCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1896
Query: 139 ERR---CMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSCRNEEXXXX 193
R C+ +T+ + C C G++ +G CVD +EC + +C+N E
Sbjct: 1897 VCRFGHCL--NTAGSFHCL-CQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFR 1953
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G + + +HC+D+DEC++ C G C N+P
Sbjct: 1954 CIC------------PPGFQVQSDHCIDIDECSEEPNLCLFG-TCTNSP 1989
Score = 48.0 bits (109), Expect = 1e-04
Identities = 53/186 (28%), Positives = 77/186 (41%), Gaps = 26/186 (13%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSD--GQTCRT-ACSANPCFGGRVPCQDLPDGRYQCG 74
LC+ RC+ T +RCE C T D G+ C+++PC G C ++P G Y C
Sbjct: 418 LCLNGRCLPTPSSYRCE-CNVGYTQDVRGECIDVDECTSSPCHHG--DCVNIP-GTYHC- 472
Query: 75 KCPSGFHGNGVE--CYRI-SC--RANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQC- 126
+C GF C + C C G C T+ +C C G+ DG+ C
Sbjct: 473 RCYPGFQATPTRQACVDVDECIVSGGLCHLG-RCVNTEGSFQC-VCNAGFELSPDGKNCV 530
Query: 127 -QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLV 183
+ C C C+ + S + C C G+ G+ C+D+DEC C +
Sbjct: 531 DHNECATSTMC-VNGVCLNEDGS--FSCL-CKPGFLLAPGGHYCMDIDECQTPGICVN-G 585
Query: 184 SCRNEE 189
C N E
Sbjct: 586 HCTNTE 591
Score = 47.2 bits (107), Expect = 2e-04
Identities = 85/324 (26%), Positives = 113/324 (34%), Gaps = 57/324 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKC- 76
LC+ C ++ F+C PG SD + + CF R Q R++ GKC
Sbjct: 1979 LCLFGTCTNSPGSFQCLCPPGFVLSD--------NGHRCFDTR---QSFCFTRFEAGKCS 2027
Query: 77 -PSGFHGNGVECYRISCRANTCFQGVSCEET-QYGPKCGS--CPTGYVG-----DGRQCQ 127
P F+ C S R + G CE Q G CP G+ D R+
Sbjct: 2028 VPKAFNTTKTRCC-CSKRPGEGW-GDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDV 2085
Query: 128 HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLVSC 185
+ C A+ P G + +T + CE CP GY + G CVD DEC + PC +C
Sbjct: 2086 NEC-AENP-GVCTNGVCVNTDGSFRCE-CPFGYSLDFTGINCVDTDECSVGHPCGQ-GTC 2141
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N G T C D+DEC+ C C NT
Sbjct: 2142 TN---VIGGFECACADGFEPGLMMT--------CEDIDECSLNPLLC--AFRCHNT---- 2184
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCN 304
+GSY+C G+ C D D + R G CVC
Sbjct: 2185 -------EGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCP 2237
Query: 305 TGW---TGNGTVCGLDRDLDGHPD 325
G G+G C D + PD
Sbjct: 2238 PGMRPLPGSGEGCTDDNECHAQPD 2261
Score = 44.4 bits (100), Expect = 0.002
Identities = 45/168 (26%), Positives = 67/168 (39%), Gaps = 21/168 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQT-CRTA--CSANPCFGGRVPCQDLPDGRYQCG 74
+C C+DT+ + C G Q S QT C C PC G C+++ G Y C
Sbjct: 1815 VCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGT--CKNII-GSYNC- 1870
Query: 75 KCPSGF----HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQH 128
C GF +G+ V+ + + C T C C G+ DG+ C
Sbjct: 1871 LCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHC-LCQDGFELTADGKNCVD 1929
Query: 129 VCDAQKPCGRERRCMP---KSTSPYYECEGCPSGYQWNGYTCVDMDEC 173
+ G C+P ++ + C CP G+Q C+D+DEC
Sbjct: 1930 TNECLSLAGT---CLPGTCQNLEGSFRCI-CPPGFQVQSDHCIDIDEC 1973
Score = 43.6 bits (98), Expect = 0.003
Identities = 66/259 (25%), Positives = 96/259 (37%), Gaps = 46/259 (17%)
Query: 69 GRYQCGKCPSGFHGNGV--ECYRIS-C--RANTCFQGVSCEETQYGPKCGSCPTGY-VGD 122
G ++C +CP+GF+ N + C + C R + C Q C +C C GY +
Sbjct: 1742 GSFRC-ECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC-KCTRGYKLSP 1799
Query: 123 GRQC--QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLIRP 178
G C ++ C CM T Y C C G+Q + C+D+DECD +P
Sbjct: 1800 GGACVGRNECREIPNVCSHGDCM--DTEGSYMCL-CHRGFQASADQTLCMDIDECDR-QP 1855
Query: 179 CDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLC 238
C + +C+N G+ T N CVD DEC R C
Sbjct: 1856 CGN-GTCKN-------IIGSYNCLCFPGFVVTHN----GDCVDFDECTTLVGQVCRFGHC 1903
Query: 239 VNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPD---SLVKRCDPSYCRRFNAVC 295
+NT GS+ C+ G + C D + SL C P C+
Sbjct: 1904 LNT-----------AGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEG-- 1950
Query: 296 GFGQKCVCNTGWTGNGTVC 314
+C+C G+ C
Sbjct: 1951 --SFRCICPPGFQVQSDHC 1967
Score = 42.7 bits (96), Expect = 0.005
Identities = 84/334 (25%), Positives = 122/334 (36%), Gaps = 59/334 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDG-QTCRTA--CSANPCFGGRVPCQDLPDGRYQCG 74
LC G CV+T F+CE PG S+ + C CS + G C + G Y C
Sbjct: 1573 LCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTL-GNYTC- 1630
Query: 75 KCPSGFH--GNGVECYRISCRANTCFQ---GVSCEETQYGPKCGSCPTGYVGDGRQCQHV 129
CP+ + G C + R + CF+ G E + C Y G+
Sbjct: 1631 VCPAEYLQVNGGNNC--MDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSY-NIGQAWNRP 1687
Query: 130 CDAQKPCGRERRCMPKSTSPYYE--CEGCPSGYQWNGYTC--VDMDECDLIRPCDDLVSC 185
C+A C P SP Y+ C G+ + +T +D+DEC I C
Sbjct: 1688 CEA---------C-PTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANGIC 1737
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N+ + G C DVDEC + C + C+N P
Sbjct: 1738 INQ----------IGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIP--- 1784
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCN 304
GSY C C Y ++ C + R P+ C + + G C+C+
Sbjct: 1785 --------GSYRC-KCTRGYKLSPGGACVGRNEC--REIPNVCSHGDCMDTEGSYMCLCH 1833
Query: 305 TGW--TGNGTVCGLDRDLDGHPDEQLPCNEPRCK 336
G+ + + T+C D+D D Q PC CK
Sbjct: 1834 RGFQASADQTLC---MDID-ECDRQ-PCGNGTCK 1862
Score = 39.5 bits (88), Expect = 0.046
Identities = 54/216 (25%), Positives = 80/216 (37%), Gaps = 34/216 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPG-SQTSDGQTCRTACSANPCFGG--RVPC-QDLPD--GRY 71
+CV C +T+ FRC+ G + +DG+ C + C+G + C + P +
Sbjct: 581 ICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKS 640
Query: 72 QCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
+C C + HG G C + + FQ + C S G DGR
Sbjct: 641 EC-CCANPDHGFGEPCQLCPAKNSAEFQAL----------CSS-GLGITTDGRDINECAL 688
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLVSCRNEE 189
+ C + ++ Y C C GY+ +G C D+DEC L D C+N
Sbjct: 689 DPEVCANG---VCENLRGSYRCV-CNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSP 744
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDEC 225
W+ T E C DVDEC
Sbjct: 745 GSYSCSCPPGFHF----WQDT------EICKDVDEC 770
Score = 37.5 bits (83), Expect = 0.19
Identities = 86/345 (24%), Positives = 114/345 (33%), Gaps = 67/345 (19%)
Query: 8 DAGSMVTPFKLCVGERCVDTDQGFRCERCPGSQTS-DGQTC--------RTACSANPCFG 58
D + LC RCV+T+ F+C G + S DG+ C T C C
Sbjct: 489 DVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLN 548
Query: 59 --GRVPCQD------LPDGRY-----QC---GKCPSGFHGNGVECYRISCRANTCF--QG 100
G C P G Y +C G C +G N +R C G
Sbjct: 549 EDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDG 608
Query: 101 VSCEETQYGPKC------GSCPTGYVGDGRQCQHVC-DAQKPCGRERRCMPKSTSPYYEC 153
C +T C GSC + G + + C + G + P S ++
Sbjct: 609 RVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQA 668
Query: 154 EGCPSGYQWNGYTCV--DMDECDLI-RPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGT 210
C SG G T D++EC L C + V C N + G
Sbjct: 669 L-CSSGL---GITTDGRDINECALDPEVCANGV-CENLRGSYRCVCNLGYEAGASG---- 719
Query: 211 GNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTT 270
+ C DVDECA C G C N+P GSY C G ++ T
Sbjct: 720 ------KDCTDVDECALNSLLCDNG-WCQNSP-----------GSYSCSCPPGFHFWQDT 761
Query: 271 RPCFDPDS-LVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
C D D L C CR N + KC + +GT C
Sbjct: 762 EICKDVDECLSSPCVSGVCR--NLAGSYTCKCGPGSRLDPSGTFC 804
Score = 35.5 bits (78), Expect = 0.75
Identities = 35/110 (31%), Positives = 50/110 (45%), Gaps = 14/110 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPG-SQTSDGQTCRTA--CS-ANPCFGGRVPCQDLPDGRYQC 73
LC +C++ G+RCE G T D + C+ C+ N C G C++LP G ++C
Sbjct: 1372 LCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFG--SCENLP-GMFRC 1428
Query: 74 GKCPSGFH--GNGVECYRISCRAN--TCFQGVSCEETQYGPKCGSCPTGY 119
C G+ G C I+ A+ C GV C T C SCP +
Sbjct: 1429 -ICNGGYELDRGGGNCTDINECADPVNCINGV-CINTPGSYLC-SCPQDF 1475
Score = 33.5 bits (73), Expect = 3.0
Identities = 29/93 (31%), Positives = 36/93 (38%), Gaps = 17/93 (18%)
Query: 216 REHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFD 275
R C+DVDEC + C G CVN P G+Y C G T + C D
Sbjct: 444 RGECIDVDECTS--SPCHHGD-CVNIP-----------GTYHCRCYPGFQATPTRQACVD 489
Query: 276 PDSLVKRCDPSYCRRFNAVCGFGQ-KCVCNTGW 307
D + C V G +CVCN G+
Sbjct: 490 VDECI--VSGGLCHLGRCVNTEGSFQCVCNAGF 520
Score = 31.9 bits (69), Expect = 9.2
Identities = 26/81 (32%), Positives = 31/81 (38%), Gaps = 8/81 (9%)
Query: 1 MHAGSMGDAGSMVTPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPC--- 56
+H G+ D LC G CV+ F C RCP G + SD A C
Sbjct: 240 IHTGACQDVDECQAVPGLCQGGSCVNMVGSFHC-RCPVGHRLSDSSAACEDYRAGACFSV 298
Query: 57 -FGGRVPCQDLPDGRYQCGKC 76
FGGR C G Y +C
Sbjct: 299 LFGGR--CAGDLAGHYTRRQC 317
>AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 1 protein.
Length = 2809
Score = 70.9 bits (166), Expect = 2e-11
Identities = 92/318 (28%), Positives = 123/318 (38%), Gaps = 50/318 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQ-TSDGQTCR--TACSANPCFGGRVPCQDLPDGRYQCG 74
LC G C +TD ++C+ PG + T+ G C CS + C ++ G +QC
Sbjct: 1081 LCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNV-IGAFQC- 1138
Query: 75 KCPSGFHG--NGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQHV 129
C +GF + C I+ CR V C T+ +C SC GY + DGR C V
Sbjct: 1139 SCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRC-SCGQGYSLMPDGRACADV 1197
Query: 130 --CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSC 185
C+ + C + + C C G+ + TCVD+DECDL C
Sbjct: 1198 DECEENPRVCDQGHC--TNMPGGHRCL-CYDGFMATPDMRTCVDVDECDLNPHICLHGDC 1254
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N + +G G C DVDEC G NC C+N P
Sbjct: 1255 ENTK-GSFVCHCQLGYMVRKGATG---------CSDVDECEVGGHNCDSHASCLNIP--- 1301
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK---RCDP-SYCRRFNAVCGFGQKC 301
GS+ C G +V C D D V RC P C V G +C
Sbjct: 1302 --------GSFSCRCLPG--WVGDGFECHDLDECVSQEHRCSPRGDCLN---VPG-SYRC 1347
Query: 302 VCNTGWTGNGTVCGLDRD 319
C G+ G+G C DRD
Sbjct: 1348 TCRQGFAGDGFFCE-DRD 1364
Score = 62.9 bits (146), Expect = 4e-09
Identities = 92/315 (29%), Positives = 117/315 (37%), Gaps = 53/315 (16%)
Query: 21 GERCVDTDQGF---RCE--RCPGSQTSDGQTCRTACSANPCFGGRVPCQDLP-DGRYQCG 74
G RC DT Q F R E +C + + R CS P G PC+ P +G
Sbjct: 2006 GHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQ 2065
Query: 75 K-CPSGFHGN--GVECYRIS---CRAN--TCFQGVSCEETQYGPKCGSCPTGYVGD--GR 124
+ CP G HG G + R C N C GV C T +C CP GY D G
Sbjct: 2066 ELCPFG-HGAVPGPDDSREDVNECAENPGVCTNGV-CVNTDGSFRC-ECPFGYSLDFTGI 2122
Query: 125 QCQHV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN-GYTCVDMDECDLIRPCDD 181
C C PCG + C + +EC C G++ TC D+DEC L P
Sbjct: 2123 NCVDTDECSVGHPCG-QGTCT--NVIGGFEC-ACADGFEPGLMMTCEDIDECSL-NPLLC 2177
Query: 182 LVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC-PRGRLCVN 240
C N E G C DVDECADG+ +C RG C N
Sbjct: 2178 AFRCHNTEGSYLCTCPAGYTLREDG----------AMCRDVDECADGQQDCHARGMECKN 2227
Query: 241 TPQYPSNPVSSLQGSYICV-PCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ 299
L G++ CV P G + C D + P C V G
Sbjct: 2228 -----------LIGTFACVCPPGMRPLPGSGEGCTDDNEC--HAQPDLCVNGRCVNTAGS 2274
Query: 300 -KCVCNTGWTGNGTV 313
+C C+ G+ + T+
Sbjct: 2275 FRCDCDEGFQPSPTL 2289
Score = 61.3 bits (142), Expect = 1e-08
Identities = 64/231 (27%), Positives = 85/231 (36%), Gaps = 33/231 (14%)
Query: 24 CVDTDQGFRCERCPGSQT--SDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCGKCPS 78
C +T F C CP DG+TC+ + C + CQ L G + C +CP
Sbjct: 2420 CKNTKGSFLCS-CPRGYLLEEDGRTCK---DLDECTSRQHNCQFLCVNTVGAFTC-RCPP 2474
Query: 79 GFHGNGVECY---RISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQHVCDAQ 133
GF + C+ S + C C T +C C G+ V G C+ V +
Sbjct: 2475 GFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRC-ECHQGFTLVSSGHGCEDVNECD 2533
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGY--TCVDMDECDLIRPCDDLVSCRNEEXX 191
P + C + Y C CP G+ + CVD +EC L P SCRN
Sbjct: 2534 GPHRCQHGCQNQLGG--YRCS-CPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGG 2590
Query: 192 XXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G ++ C DVDECA R C C NTP
Sbjct: 2591 FRCVCPS----------GFDFDQALGGCQDVDECAGRRGPCSYS--CANTP 2629
Score = 57.6 bits (133), Expect = 2e-07
Identities = 79/293 (26%), Positives = 107/293 (36%), Gaps = 51/293 (17%)
Query: 17 KLCVGERCVDTDQGFRCERCPGSQ-TSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQC 73
++C C + G RC G T D +TC C NP C++ G + C
Sbjct: 1205 RVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTK-GSFVC 1263
Query: 74 GKCPSGF--HGNGVECYRIS-CRA--NTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQH 128
C G+ C + C + C SC C C G+VGDG +C
Sbjct: 1264 -HCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSC-RCLPGWVGDGFECH- 1320
Query: 129 VCDAQKPCGRERRCMPK----STSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDLV 183
D + +E RC P+ + Y C C G+ +G+ C D DEC + + CD+
Sbjct: 1321 --DLDECVSQEHRCSPRGDCLNVPGSYRCT-CRQGFAGDGFFCEDRDECAENVDLCDN-G 1376
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQ 243
C N G+ T + R C DVDECA G C G C N P
Sbjct: 1377 QCLN-------APGGYRCECEMGFDPTEDHRA---CQDVDECAQGNL-CAFGS-CENLP- 1423
Query: 244 YPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRC-DPSYCRRFNAVC 295
G + C+ GG+ C D + C DP C N VC
Sbjct: 1424 ----------GMFRCICNGGYELDRGGGNCTD----INECADPVNC--INGVC 1460
Score = 55.6 bits (128), Expect = 7e-07
Identities = 66/239 (27%), Positives = 94/239 (39%), Gaps = 36/239 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACS-ANPC-FGGR-----VPCQDLPDGR 70
+C+ C +T F C G G T CS + C GG C ++P G
Sbjct: 1248 ICLHGDCENTKGSFVCHCQLGYMVRKGAT---GCSDVDECEVGGHNCDSHASCLNIP-GS 1303
Query: 71 YQCGKCPSGFHGNGVECYRIS-C--RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ 127
+ C +C G+ G+G EC+ + C + + C C +C +C G+ GDG C+
Sbjct: 1304 FSC-RCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRC-TCRQGFAGDGFFCE 1361
Query: 128 H--VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLV 183
C +C+ + Y CE C G+ + C D+DEC C
Sbjct: 1362 DRDECAENVDLCDNGQCL--NAPGGYRCE-CEMGFDPTEDHRACQDVDECAQGNLCA-FG 1417
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
SC N RG GN C D++ECAD NC G +C+NTP
Sbjct: 1418 SCENLPGMFRCICNGGYELD----RGGGN------CTDINECAD-PVNCING-VCINTP 1464
Score = 55.2 bits (127), Expect = 9e-07
Identities = 88/361 (24%), Positives = 128/361 (35%), Gaps = 51/361 (14%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQ----TCRTACSANPCFGGRVPCQDLPDGRYQC 73
LC C +T F C C G D Q T C +P G+ C + P G ++C
Sbjct: 996 LCTHGTCRNTVGSFHCA-CAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTP-GSFEC 1053
Query: 74 GKCPSGFHGNGV---ECYRIS--CRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQC 126
+C G+ + C + R +G +C T KC CP G+ G C
Sbjct: 1054 -ECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKC-QCPPGHELTAKGTAC 1111
Query: 127 QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRP-CDDLV 183
+ + + G + ++C C +G+Q + CVD++EC + CD V
Sbjct: 1112 EDIDECSLSDGLCPHGQCVNVIGAFQCS-CHAGFQSTPDRQGCVDINECRVQNGGCD--V 1168
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRRE--------HCVDVDE-----CADGRA 230
C N E G + E HC ++ C DG
Sbjct: 1169 HCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFM 1228
Query: 231 NCPRGRLCVNTPQYPSNP-------VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLV--- 280
P R CV+ + NP + +GS++C G+ C D D
Sbjct: 1229 ATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGG 1288
Query: 281 KRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRCKKDNC 340
CD S+ N F C C GW G+G C DLD ++ C+ PR N
Sbjct: 1289 HNCD-SHASCLNIPGSF--SCRCLPGWVGDGFEC---HDLDECVSQEHRCS-PRGDCLNV 1341
Query: 341 P 341
P
Sbjct: 1342 P 1342
Score = 54.8 bits (126), Expect = 1e-06
Identities = 77/300 (25%), Positives = 107/300 (35%), Gaps = 51/300 (17%)
Query: 24 CVDTDQGFRCERCPG-SQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C++T+ +RC G S DG+ C C NP + C ++P G ++C C GF
Sbjct: 1170 CINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGG-HRC-LCYDGF 1227
Query: 81 HGNG-----VECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY-VGDGRQ-CQHVCDAQ 133
V+ + C G CE T+ C C GY V G C V + +
Sbjct: 1228 MATPDMRTCVDVDECDLNPHICLHG-DCENTKGSFVC-HCQLGYMVRKGATGCSDVDECE 1285
Query: 134 ---KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDLVSCRNEE 189
C C+ S + C C G+ +G+ C D+DEC C C N
Sbjct: 1286 VGGHNCDSHASCLNIPGS--FSCR-CLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVP 1342
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPV 249
QG+ G G C D DECA+ C G+ C+N P
Sbjct: 1343 GSYRCTCR-------QGFAGDGF-----FCEDRDECAENVDLCDNGQ-CLNAP------- 1382
Query: 250 SSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK--RCDPSYCRRFNAVCGFGQKCVCNTGW 307
G Y C G R C D D + C C + +C+CN G+
Sbjct: 1383 ----GGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMF----RCICNGGY 1434
Score = 54.8 bits (126), Expect = 1e-06
Identities = 90/342 (26%), Positives = 126/342 (36%), Gaps = 67/342 (19%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGG--RVPCQDLPDG-----R 70
LCV RCV+T FRC+ G Q S T PCF + C+ L R
Sbjct: 2262 LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTR 2321
Query: 71 YQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCP--TGYVGDGRQCQH 128
+C C G G G C + ++ + CP +GY +GR
Sbjct: 2322 AEC--CCGGGRGWGPRCELCPLPGTSAYRKL-------------CPHGSGYTAEGRDVDE 2366
Query: 129 VCDAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLI-RPCDDLVSC 185
C C+ S + C C +GY TC+DMDEC + +PC L C
Sbjct: 2367 -CRMLAHLCAHGECINSLGS--FRCH-CQAGYTPDATATTCLDMDECSQVPKPCTFL--C 2420
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
+N + RG E C D+DEC + NC LCVNT
Sbjct: 2421 KNTKGSFLCSCP----------RGYLLEEDGRTCKDLDECTSRQHNCQ--FLCVNT---- 2464
Query: 246 SNPVSSLQGSYIC-VPCGGHYYVNTTRPCFDPDSLVKRCDP--SYCRRFNAVCGFGQKCV 302
G++ C P G + + CFD D + P ++ N F +C
Sbjct: 2465 -------VGAFTCRCPPG---FTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSF--RCE 2512
Query: 303 CNTGWT--GNGTVCGLDRDLDGHPDEQLPC-NEPRCKKDNCP 341
C+ G+T +G C + DG Q C N+ + +CP
Sbjct: 2513 CHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCP 2554
Score = 48.4 bits (110), Expect = 1e-04
Identities = 56/229 (24%), Positives = 87/229 (37%), Gaps = 29/229 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTC--RTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
C++ +RC+ G + S G C R C P C D +G Y C C GF
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMD-TEGSYMC-LCHRGFQ 1837
Query: 82 GNGVE--CYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGR 138
+ + C I C C G +C+ C P V C + G+
Sbjct: 1838 ASADQTLCMDIDECDRQPCGNG-TCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1896
Query: 139 ERR---CMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSCRNEEXXXX 193
R C+ +T+ + C C G++ +G CVD +EC + +C+N E
Sbjct: 1897 VCRFGHCL--NTAGSFHCL-CQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFR 1953
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G + + +HC+D+DEC++ C G C N+P
Sbjct: 1954 CIC------------PPGFQVQSDHCIDIDECSEEPNLCLFG-TCTNSP 1989
Score = 48.0 bits (109), Expect = 1e-04
Identities = 53/186 (28%), Positives = 77/186 (41%), Gaps = 26/186 (13%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSD--GQTCRT-ACSANPCFGGRVPCQDLPDGRYQCG 74
LC+ RC+ T +RCE C T D G+ C+++PC G C ++P G Y C
Sbjct: 418 LCLNGRCLPTPSSYRCE-CNVGYTQDVRGECIDVDECTSSPCHHG--DCVNIP-GTYHC- 472
Query: 75 KCPSGFHGNGVE--CYRI-SC--RANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQC- 126
+C GF C + C C G C T+ +C C G+ DG+ C
Sbjct: 473 RCYPGFQATPTRQACVDVDECIVSGGLCHLG-RCVNTEGSFQC-VCNAGFELSPDGKNCV 530
Query: 127 -QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLV 183
+ C C C+ + S + C C G+ G+ C+D+DEC C +
Sbjct: 531 DHNECATSTMC-VNGVCLNEDGS--FSCL-CKPGFLLAPGGHYCMDIDECQTPGICVN-G 585
Query: 184 SCRNEE 189
C N E
Sbjct: 586 HCTNTE 591
Score = 47.2 bits (107), Expect = 2e-04
Identities = 85/324 (26%), Positives = 113/324 (34%), Gaps = 57/324 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKC- 76
LC+ C ++ F+C PG SD + + CF R Q R++ GKC
Sbjct: 1979 LCLFGTCTNSPGSFQCLCPPGFVLSD--------NGHRCFDTR---QSFCFTRFEAGKCS 2027
Query: 77 -PSGFHGNGVECYRISCRANTCFQGVSCEET-QYGPKCGS--CPTGYVG-----DGRQCQ 127
P F+ C S R + G CE Q G CP G+ D R+
Sbjct: 2028 VPKAFNTTKTRCC-CSKRPGEGW-GDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDV 2085
Query: 128 HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLVSC 185
+ C A+ P G + +T + CE CP GY + G CVD DEC + PC +C
Sbjct: 2086 NEC-AENP-GVCTNGVCVNTDGSFRCE-CPFGYSLDFTGINCVDTDECSVGHPCGQ-GTC 2141
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N G T C D+DEC+ C C NT
Sbjct: 2142 TN---VIGGFECACADGFEPGLMMT--------CEDIDECSLNPLLC--AFRCHNT---- 2184
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCN 304
+GSY+C G+ C D D + R G CVC
Sbjct: 2185 -------EGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCP 2237
Query: 305 TGW---TGNGTVCGLDRDLDGHPD 325
G G+G C D + PD
Sbjct: 2238 PGMRPLPGSGEGCTDDNECHAQPD 2261
Score = 44.4 bits (100), Expect = 0.002
Identities = 45/168 (26%), Positives = 67/168 (39%), Gaps = 21/168 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQT-CRTA--CSANPCFGGRVPCQDLPDGRYQCG 74
+C C+DT+ + C G Q S QT C C PC G C+++ G Y C
Sbjct: 1815 VCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGT--CKNII-GSYNC- 1870
Query: 75 KCPSGF----HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQH 128
C GF +G+ V+ + + C T C C G+ DG+ C
Sbjct: 1871 LCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHC-LCQDGFELTADGKNCVD 1929
Query: 129 VCDAQKPCGRERRCMP---KSTSPYYECEGCPSGYQWNGYTCVDMDEC 173
+ G C+P ++ + C CP G+Q C+D+DEC
Sbjct: 1930 TNECLSLAGT---CLPGTCQNLEGSFRCI-CPPGFQVQSDHCIDIDEC 1973
Score = 43.6 bits (98), Expect = 0.003
Identities = 66/259 (25%), Positives = 96/259 (37%), Gaps = 46/259 (17%)
Query: 69 GRYQCGKCPSGFHGNGV--ECYRIS-C--RANTCFQGVSCEETQYGPKCGSCPTGY-VGD 122
G ++C +CP+GF+ N + C + C R + C Q C +C C GY +
Sbjct: 1742 GSFRC-ECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC-KCTRGYKLSP 1799
Query: 123 GRQC--QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLIRP 178
G C ++ C CM T Y C C G+Q + C+D+DECD +P
Sbjct: 1800 GGACVGRNECREIPNVCSHGDCM--DTEGSYMCL-CHRGFQASADQTLCMDIDECDR-QP 1855
Query: 179 CDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLC 238
C + +C+N G+ T N CVD DEC R C
Sbjct: 1856 CGN-GTCKN-------IIGSYNCLCFPGFVVTHN----GDCVDFDECTTLVGQVCRFGHC 1903
Query: 239 VNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPD---SLVKRCDPSYCRRFNAVC 295
+NT GS+ C+ G + C D + SL C P C+
Sbjct: 1904 LNT-----------AGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEG-- 1950
Query: 296 GFGQKCVCNTGWTGNGTVC 314
+C+C G+ C
Sbjct: 1951 --SFRCICPPGFQVQSDHC 1967
Score = 42.7 bits (96), Expect = 0.005
Identities = 84/334 (25%), Positives = 122/334 (36%), Gaps = 59/334 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDG-QTCRTA--CSANPCFGGRVPCQDLPDGRYQCG 74
LC G CV+T F+CE PG S+ + C CS + G C + G Y C
Sbjct: 1573 LCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTL-GNYTC- 1630
Query: 75 KCPSGFH--GNGVECYRISCRANTCFQ---GVSCEETQYGPKCGSCPTGYVGDGRQCQHV 129
CP+ + G C + R + CF+ G E + C Y G+
Sbjct: 1631 VCPAEYLQVNGGNNC--MDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSY-NIGQAWNRP 1687
Query: 130 CDAQKPCGRERRCMPKSTSPYYE--CEGCPSGYQWNGYTC--VDMDECDLIRPCDDLVSC 185
C+A C P SP Y+ C G+ + +T +D+DEC I C
Sbjct: 1688 CEA---------C-PTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANGIC 1737
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N+ + G C DVDEC + C + C+N P
Sbjct: 1738 INQ----------IGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIP--- 1784
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCN 304
GSY C C Y ++ C + R P+ C + + G C+C+
Sbjct: 1785 --------GSYRC-KCTRGYKLSPGGACVGRNEC--REIPNVCSHGDCMDTEGSYMCLCH 1833
Query: 305 TGW--TGNGTVCGLDRDLDGHPDEQLPCNEPRCK 336
G+ + + T+C D+D D Q PC CK
Sbjct: 1834 RGFQASADQTLC---MDID-ECDRQ-PCGNGTCK 1862
Score = 39.5 bits (88), Expect = 0.046
Identities = 54/216 (25%), Positives = 80/216 (37%), Gaps = 34/216 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPG-SQTSDGQTCRTACSANPCFGG--RVPC-QDLPD--GRY 71
+CV C +T+ FRC+ G + +DG+ C + C+G + C + P +
Sbjct: 581 ICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKS 640
Query: 72 QCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
+C C + HG G C + + FQ + C S G DGR
Sbjct: 641 EC-CCANPDHGFGEPCQLCPAKNSAEFQAL----------CSS-GLGITTDGRDINECAL 688
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLVSCRNEE 189
+ C + ++ Y C C GY+ +G C D+DEC L D C+N
Sbjct: 689 DPEVCANG---VCENLRGSYRCV-CNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSP 744
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDEC 225
W+ T E C DVDEC
Sbjct: 745 GSYSCSCPPGFHF----WQDT------EICKDVDEC 770
Score = 37.5 bits (83), Expect = 0.19
Identities = 86/345 (24%), Positives = 114/345 (33%), Gaps = 67/345 (19%)
Query: 8 DAGSMVTPFKLCVGERCVDTDQGFRCERCPGSQTS-DGQTC--------RTACSANPCFG 58
D + LC RCV+T+ F+C G + S DG+ C T C C
Sbjct: 489 DVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLN 548
Query: 59 --GRVPCQD------LPDGRY-----QC---GKCPSGFHGNGVECYRISCRANTCF--QG 100
G C P G Y +C G C +G N +R C G
Sbjct: 549 EDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDG 608
Query: 101 VSCEETQYGPKC------GSCPTGYVGDGRQCQHVC-DAQKPCGRERRCMPKSTSPYYEC 153
C +T C GSC + G + + C + G + P S ++
Sbjct: 609 RVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQA 668
Query: 154 EGCPSGYQWNGYTCV--DMDECDLI-RPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGT 210
C SG G T D++EC L C + V C N + G
Sbjct: 669 L-CSSGL---GITTDGRDINECALDPEVCANGV-CENLRGSYRCVCNLGYEAGASG---- 719
Query: 211 GNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTT 270
+ C DVDECA C G C N+P GSY C G ++ T
Sbjct: 720 ------KDCTDVDECALNSLLCDNG-WCQNSP-----------GSYSCSCPPGFHFWQDT 761
Query: 271 RPCFDPDS-LVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
C D D L C CR N + KC + +GT C
Sbjct: 762 EICKDVDECLSSPCVSGVCR--NLAGSYTCKCGPGSRLDPSGTFC 804
Score = 35.5 bits (78), Expect = 0.75
Identities = 35/110 (31%), Positives = 50/110 (45%), Gaps = 14/110 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPG-SQTSDGQTCRTA--CS-ANPCFGGRVPCQDLPDGRYQC 73
LC +C++ G+RCE G T D + C+ C+ N C G C++LP G ++C
Sbjct: 1372 LCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFG--SCENLP-GMFRC 1428
Query: 74 GKCPSGFH--GNGVECYRISCRAN--TCFQGVSCEETQYGPKCGSCPTGY 119
C G+ G C I+ A+ C GV C T C SCP +
Sbjct: 1429 -ICNGGYELDRGGGNCTDINECADPVNCINGV-CINTPGSYLC-SCPQDF 1475
Score = 33.5 bits (73), Expect = 3.0
Identities = 29/93 (31%), Positives = 36/93 (38%), Gaps = 17/93 (18%)
Query: 216 REHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFD 275
R C+DVDEC + C G CVN P G+Y C G T + C D
Sbjct: 444 RGECIDVDECTS--SPCHHGD-CVNIP-----------GTYHCRCYPGFQATPTRQACVD 489
Query: 276 PDSLVKRCDPSYCRRFNAVCGFGQ-KCVCNTGW 307
D + C V G +CVCN G+
Sbjct: 490 VDECI--VSGGLCHLGRCVNTEGSFQCVCNAGF 520
Score = 31.9 bits (69), Expect = 9.2
Identities = 26/81 (32%), Positives = 31/81 (38%), Gaps = 8/81 (9%)
Query: 1 MHAGSMGDAGSMVTPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPC--- 56
+H G+ D LC G CV+ F C RCP G + SD A C
Sbjct: 240 IHTGACQDVDECQAVPGLCQGGSCVNMVGSFHC-RCPVGHRLSDSSAACEDYRAGACFSV 298
Query: 57 -FGGRVPCQDLPDGRYQCGKC 76
FGGR C G Y +C
Sbjct: 299 LFGGR--CAGDLAGHYTRRQC 317
>AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 70.9 bits (166), Expect = 2e-11
Identities = 92/318 (28%), Positives = 123/318 (38%), Gaps = 50/318 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQ-TSDGQTCR--TACSANPCFGGRVPCQDLPDGRYQCG 74
LC G C +TD ++C+ PG + T+ G C CS + C ++ G +QC
Sbjct: 1081 LCWGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNV-IGAFQC- 1138
Query: 75 KCPSGFHG--NGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQHV 129
C +GF + C I+ CR V C T+ +C SC GY + DGR C V
Sbjct: 1139 SCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRC-SCGQGYSLMPDGRACADV 1197
Query: 130 --CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSC 185
C+ + C + + C C G+ + TCVD+DECDL C
Sbjct: 1198 DECEENPRVCDQGHC--TNMPGGHRCL-CYDGFMATPDMRTCVDVDECDLNPHICLHGDC 1254
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N + +G G C DVDEC G NC C+N P
Sbjct: 1255 ENTK-GSFVCHCQLGYMVRKGATG---------CSDVDECEVGGHNCDSHASCLNIP--- 1301
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK---RCDP-SYCRRFNAVCGFGQKC 301
GS+ C G +V C D D V RC P C V G +C
Sbjct: 1302 --------GSFSCRCLPG--WVGDGFECHDLDECVSQEHRCSPRGDCLN---VPG-SYRC 1347
Query: 302 VCNTGWTGNGTVCGLDRD 319
C G+ G+G C DRD
Sbjct: 1348 TCRQGFAGDGFFCE-DRD 1364
Score = 62.9 bits (146), Expect = 4e-09
Identities = 92/315 (29%), Positives = 117/315 (37%), Gaps = 53/315 (16%)
Query: 21 GERCVDTDQGF---RCE--RCPGSQTSDGQTCRTACSANPCFGGRVPCQDLP-DGRYQCG 74
G RC DT Q F R E +C + + R CS P G PC+ P +G
Sbjct: 2006 GHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQ 2065
Query: 75 K-CPSGFHGN--GVECYRIS---CRAN--TCFQGVSCEETQYGPKCGSCPTGYVGD--GR 124
+ CP G HG G + R C N C GV C T +C CP GY D G
Sbjct: 2066 ELCPFG-HGAVPGPDDSREDVNECAENPGVCTNGV-CVNTDGSFRC-ECPFGYSLDFTGI 2122
Query: 125 QCQHV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN-GYTCVDMDECDLIRPCDD 181
C C PCG + C + +EC C G++ TC D+DEC L P
Sbjct: 2123 NCVDTDECSVGHPCG-QGTCT--NVIGGFEC-ACADGFEPGLMMTCEDIDECSL-NPLLC 2177
Query: 182 LVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC-PRGRLCVN 240
C N E G C DVDECADG+ +C RG C N
Sbjct: 2178 AFRCHNTEGSYLCTCPAGYTLREDG----------AMCRDVDECADGQQDCHARGMECKN 2227
Query: 241 TPQYPSNPVSSLQGSYICV-PCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ 299
L G++ CV P G + C D + P C V G
Sbjct: 2228 -----------LIGTFACVCPPGMRPLPGSGEGCTDDNEC--HAQPDLCVNGRCVNTAGS 2274
Query: 300 -KCVCNTGWTGNGTV 313
+C C+ G+ + T+
Sbjct: 2275 FRCDCDEGFQPSPTL 2289
Score = 61.3 bits (142), Expect = 1e-08
Identities = 64/231 (27%), Positives = 85/231 (36%), Gaps = 33/231 (14%)
Query: 24 CVDTDQGFRCERCPGSQT--SDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCGKCPS 78
C +T F C CP DG+TC+ + C + CQ L G + C +CP
Sbjct: 2420 CKNTKGSFLCS-CPRGYLLEEDGRTCK---DLDECTSRQHNCQFLCVNTVGAFTC-RCPP 2474
Query: 79 GFHGNGVECY---RISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQHVCDAQ 133
GF + C+ S + C C T +C C G+ V G C+ V +
Sbjct: 2475 GFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRC-ECHQGFTLVSSGHGCEDVNECD 2533
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGY--TCVDMDECDLIRPCDDLVSCRNEEXX 191
P + C + Y C CP G+ + CVD +EC L P SCRN
Sbjct: 2534 GPHRCQHGCQNQLGG--YRCS-CPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGG 2590
Query: 192 XXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G ++ C DVDECA R C C NTP
Sbjct: 2591 FRCVCPS----------GFDFDQALGGCQDVDECAGRRGPCSYS--CANTP 2629
Score = 57.6 bits (133), Expect = 2e-07
Identities = 79/293 (26%), Positives = 107/293 (36%), Gaps = 51/293 (17%)
Query: 17 KLCVGERCVDTDQGFRCERCPGSQ-TSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQC 73
++C C + G RC G T D +TC C NP C++ G + C
Sbjct: 1205 RVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTK-GSFVC 1263
Query: 74 GKCPSGF--HGNGVECYRIS-CRA--NTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQH 128
C G+ C + C + C SC C C G+VGDG +C
Sbjct: 1264 -HCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSC-RCLPGWVGDGFECH- 1320
Query: 129 VCDAQKPCGRERRCMPK----STSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDLV 183
D + +E RC P+ + Y C C G+ +G+ C D DEC + + CD+
Sbjct: 1321 --DLDECVSQEHRCSPRGDCLNVPGSYRCT-CRQGFAGDGFFCEDRDECAENVDLCDN-G 1376
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQ 243
C N G+ T + R C DVDECA G C G C N P
Sbjct: 1377 QCLN-------APGGYRCECEMGFDPTEDHRA---CQDVDECAQGNL-CAFGS-CENLP- 1423
Query: 244 YPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRC-DPSYCRRFNAVC 295
G + C+ GG+ C D + C DP C N VC
Sbjct: 1424 ----------GMFRCICNGGYELDRGGGNCTD----INECADPVNC--INGVC 1460
Score = 55.6 bits (128), Expect = 7e-07
Identities = 66/239 (27%), Positives = 94/239 (39%), Gaps = 36/239 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACS-ANPC-FGGR-----VPCQDLPDGR 70
+C+ C +T F C G G T CS + C GG C ++P G
Sbjct: 1248 ICLHGDCENTKGSFVCHCQLGYMVRKGAT---GCSDVDECEVGGHNCDSHASCLNIP-GS 1303
Query: 71 YQCGKCPSGFHGNGVECYRIS-C--RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ 127
+ C +C G+ G+G EC+ + C + + C C +C +C G+ GDG C+
Sbjct: 1304 FSC-RCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRC-TCRQGFAGDGFFCE 1361
Query: 128 H--VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLV 183
C +C+ + Y CE C G+ + C D+DEC C
Sbjct: 1362 DRDECAENVDLCDNGQCL--NAPGGYRCE-CEMGFDPTEDHRACQDVDECAQGNLCA-FG 1417
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
SC N RG GN C D++ECAD NC G +C+NTP
Sbjct: 1418 SCENLPGMFRCICNGGYELD----RGGGN------CTDINECAD-PVNCING-VCINTP 1464
Score = 54.8 bits (126), Expect = 1e-06
Identities = 77/300 (25%), Positives = 107/300 (35%), Gaps = 51/300 (17%)
Query: 24 CVDTDQGFRCERCPG-SQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C++T+ +RC G S DG+ C C NP + C ++P G ++C C GF
Sbjct: 1170 CINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGG-HRC-LCYDGF 1227
Query: 81 HGNG-----VECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY-VGDGRQ-CQHVCDAQ 133
V+ + C G CE T+ C C GY V G C V + +
Sbjct: 1228 MATPDMRTCVDVDECDLNPHICLHG-DCENTKGSFVC-HCQLGYMVRKGATGCSDVDECE 1285
Query: 134 ---KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDLVSCRNEE 189
C C+ S + C C G+ +G+ C D+DEC C C N
Sbjct: 1286 VGGHNCDSHASCLNIPGS--FSCR-CLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVP 1342
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPV 249
QG+ G G C D DECA+ C G+ C+N P
Sbjct: 1343 GSYRCTCR-------QGFAGDGF-----FCEDRDECAENVDLCDNGQ-CLNAP------- 1382
Query: 250 SSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK--RCDPSYCRRFNAVCGFGQKCVCNTGW 307
G Y C G R C D D + C C + +C+CN G+
Sbjct: 1383 ----GGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMF----RCICNGGY 1434
Score = 54.8 bits (126), Expect = 1e-06
Identities = 90/342 (26%), Positives = 126/342 (36%), Gaps = 67/342 (19%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGG--RVPCQDLPDG-----R 70
LCV RCV+T FRC+ G Q S T PCF + C+ L R
Sbjct: 2262 LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTR 2321
Query: 71 YQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCP--TGYVGDGRQCQH 128
+C C G G G C + ++ + CP +GY +GR
Sbjct: 2322 AEC--CCGGGRGWGPRCELCPLPGTSAYRKL-------------CPHGSGYTAEGRDVDE 2366
Query: 129 VCDAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLI-RPCDDLVSC 185
C C+ S + C C +GY TC+DMDEC + +PC L C
Sbjct: 2367 -CRMLAHLCAHGECINSLGS--FRCH-CQAGYTPDATATTCLDMDECSQVPKPCTFL--C 2420
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
+N + RG E C D+DEC + NC LCVNT
Sbjct: 2421 KNTKGSFLCSCP----------RGYLLEEDGRTCKDLDECTSRQHNCQ--FLCVNT---- 2464
Query: 246 SNPVSSLQGSYIC-VPCGGHYYVNTTRPCFDPDSLVKRCDP--SYCRRFNAVCGFGQKCV 302
G++ C P G + + CFD D + P ++ N F +C
Sbjct: 2465 -------VGAFTCRCPPG---FTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSF--RCE 2512
Query: 303 CNTGWT--GNGTVCGLDRDLDGHPDEQLPC-NEPRCKKDNCP 341
C+ G+T +G C + DG Q C N+ + +CP
Sbjct: 2513 CHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCP 2554
Score = 54.4 bits (125), Expect = 2e-06
Identities = 89/362 (24%), Positives = 130/362 (35%), Gaps = 53/362 (14%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQ----TCRTACSANPCFGGRVPCQDLPDGRYQC 73
LC C +T F C C G D Q T C +P G+ C + P G ++C
Sbjct: 996 LCTHGTCRNTVGSFHCA-CAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTP-GSFEC 1053
Query: 74 GKCPSGFHGNGV---ECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGY--VGDGRQ 125
+C G+ + C + C + C+ G +C T KC CP G+ G
Sbjct: 1054 -ECFPGYESGFMLMKNCMDVDECARDPLLCWGG-TCTNTDGSYKC-QCPPGHELTAKGTA 1110
Query: 126 CQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRP-CDDL 182
C+ + + G + ++C C +G+Q + CVD++EC + CD
Sbjct: 1111 CEDIDECSLSDGLCPHGQCVNVIGAFQCS-CHAGFQSTPDRQGCVDINECRVQNGGCD-- 1167
Query: 183 VSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRRE--------HCVDVDE-----CADGR 229
V C N E G + E HC ++ C DG
Sbjct: 1168 VHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGF 1227
Query: 230 ANCPRGRLCVNTPQYPSNP-------VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLV-- 280
P R CV+ + NP + +GS++C G+ C D D
Sbjct: 1228 MATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVG 1287
Query: 281 -KRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRCKKDN 339
CD S+ N F C C GW G+G C DLD ++ C+ PR N
Sbjct: 1288 GHNCD-SHASCLNIPGSF--SCRCLPGWVGDGFEC---HDLDECVSQEHRCS-PRGDCLN 1340
Query: 340 CP 341
P
Sbjct: 1341 VP 1342
Score = 48.4 bits (110), Expect = 1e-04
Identities = 56/229 (24%), Positives = 87/229 (37%), Gaps = 29/229 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTC--RTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
C++ +RC+ G + S G C R C P C D +G Y C C GF
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMD-TEGSYMC-LCHRGFQ 1837
Query: 82 GNGVE--CYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGR 138
+ + C I C C G +C+ C P V C + G+
Sbjct: 1838 ASADQTLCMDIDECDRQPCGNG-TCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1896
Query: 139 ERR---CMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSCRNEEXXXX 193
R C+ +T+ + C C G++ +G CVD +EC + +C+N E
Sbjct: 1897 VCRFGHCL--NTAGSFHCL-CQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFR 1953
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G + + +HC+D+DEC++ C G C N+P
Sbjct: 1954 CIC------------PPGFQVQSDHCIDIDECSEEPNLCLFG-TCTNSP 1989
Score = 48.0 bits (109), Expect = 1e-04
Identities = 53/186 (28%), Positives = 77/186 (41%), Gaps = 26/186 (13%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSD--GQTCRT-ACSANPCFGGRVPCQDLPDGRYQCG 74
LC+ RC+ T +RCE C T D G+ C+++PC G C ++P G Y C
Sbjct: 418 LCLNGRCLPTPSSYRCE-CNVGYTQDVRGECIDVDECTSSPCHHG--DCVNIP-GTYHC- 472
Query: 75 KCPSGFHGNGVE--CYRI-SC--RANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQC- 126
+C GF C + C C G C T+ +C C G+ DG+ C
Sbjct: 473 RCYPGFQATPTRQACVDVDECIVSGGLCHLG-RCVNTEGSFQC-VCNAGFELSPDGKNCV 530
Query: 127 -QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLV 183
+ C C C+ + S + C C G+ G+ C+D+DEC C +
Sbjct: 531 DHNECATSTMC-VNGVCLNEDGS--FSCL-CKPGFLLAPGGHYCMDIDECQTPGICVN-G 585
Query: 184 SCRNEE 189
C N E
Sbjct: 586 HCTNTE 591
Score = 47.2 bits (107), Expect = 2e-04
Identities = 85/324 (26%), Positives = 113/324 (34%), Gaps = 57/324 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKC- 76
LC+ C ++ F+C PG SD + + CF R Q R++ GKC
Sbjct: 1979 LCLFGTCTNSPGSFQCLCPPGFVLSD--------NGHRCFDTR---QSFCFTRFEAGKCS 2027
Query: 77 -PSGFHGNGVECYRISCRANTCFQGVSCEET-QYGPKCGS--CPTGYVG-----DGRQCQ 127
P F+ C S R + G CE Q G CP G+ D R+
Sbjct: 2028 VPKAFNTTKTRCC-CSKRPGEGW-GDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDV 2085
Query: 128 HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLVSC 185
+ C A+ P G + +T + CE CP GY + G CVD DEC + PC +C
Sbjct: 2086 NEC-AENP-GVCTNGVCVNTDGSFRCE-CPFGYSLDFTGINCVDTDECSVGHPCGQ-GTC 2141
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N G T C D+DEC+ C C NT
Sbjct: 2142 TN---VIGGFECACADGFEPGLMMT--------CEDIDECSLNPLLC--AFRCHNT---- 2184
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCN 304
+GSY+C G+ C D D + R G CVC
Sbjct: 2185 -------EGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCP 2237
Query: 305 TGW---TGNGTVCGLDRDLDGHPD 325
G G+G C D + PD
Sbjct: 2238 PGMRPLPGSGEGCTDDNECHAQPD 2261
Score = 44.4 bits (100), Expect = 0.002
Identities = 45/168 (26%), Positives = 67/168 (39%), Gaps = 21/168 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQT-CRTA--CSANPCFGGRVPCQDLPDGRYQCG 74
+C C+DT+ + C G Q S QT C C PC G C+++ G Y C
Sbjct: 1815 VCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGT--CKNII-GSYNC- 1870
Query: 75 KCPSGF----HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQH 128
C GF +G+ V+ + + C T C C G+ DG+ C
Sbjct: 1871 LCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHC-LCQDGFELTADGKNCVD 1929
Query: 129 VCDAQKPCGRERRCMP---KSTSPYYECEGCPSGYQWNGYTCVDMDEC 173
+ G C+P ++ + C CP G+Q C+D+DEC
Sbjct: 1930 TNECLSLAGT---CLPGTCQNLEGSFRCI-CPPGFQVQSDHCIDIDEC 1973
Score = 43.6 bits (98), Expect = 0.003
Identities = 66/259 (25%), Positives = 96/259 (37%), Gaps = 46/259 (17%)
Query: 69 GRYQCGKCPSGFHGNGV--ECYRIS-C--RANTCFQGVSCEETQYGPKCGSCPTGY-VGD 122
G ++C +CP+GF+ N + C + C R + C Q C +C C GY +
Sbjct: 1742 GSFRC-ECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC-KCTRGYKLSP 1799
Query: 123 GRQC--QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLIRP 178
G C ++ C CM T Y C C G+Q + C+D+DECD +P
Sbjct: 1800 GGACVGRNECREIPNVCSHGDCM--DTEGSYMCL-CHRGFQASADQTLCMDIDECDR-QP 1855
Query: 179 CDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLC 238
C + +C+N G+ T N CVD DEC R C
Sbjct: 1856 CGN-GTCKN-------IIGSYNCLCFPGFVVTHN----GDCVDFDECTTLVGQVCRFGHC 1903
Query: 239 VNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPD---SLVKRCDPSYCRRFNAVC 295
+NT GS+ C+ G + C D + SL C P C+
Sbjct: 1904 LNT-----------AGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEG-- 1950
Query: 296 GFGQKCVCNTGWTGNGTVC 314
+C+C G+ C
Sbjct: 1951 --SFRCICPPGFQVQSDHC 1967
Score = 42.7 bits (96), Expect = 0.005
Identities = 84/334 (25%), Positives = 122/334 (36%), Gaps = 59/334 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDG-QTCRTA--CSANPCFGGRVPCQDLPDGRYQCG 74
LC G CV+T F+CE PG S+ + C CS + G C + G Y C
Sbjct: 1573 LCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTL-GNYTC- 1630
Query: 75 KCPSGFH--GNGVECYRISCRANTCFQ---GVSCEETQYGPKCGSCPTGYVGDGRQCQHV 129
CP+ + G C + R + CF+ G E + C Y G+
Sbjct: 1631 VCPAEYLQVNGGNNC--MDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSY-NIGQAWNRP 1687
Query: 130 CDAQKPCGRERRCMPKSTSPYYE--CEGCPSGYQWNGYTC--VDMDECDLIRPCDDLVSC 185
C+A C P SP Y+ C G+ + +T +D+DEC I C
Sbjct: 1688 CEA---------C-PTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANGIC 1737
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N+ + G C DVDEC + C + C+N P
Sbjct: 1738 INQ----------IGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIP--- 1784
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCN 304
GSY C C Y ++ C + R P+ C + + G C+C+
Sbjct: 1785 --------GSYRC-KCTRGYKLSPGGACVGRNEC--REIPNVCSHGDCMDTEGSYMCLCH 1833
Query: 305 TGW--TGNGTVCGLDRDLDGHPDEQLPCNEPRCK 336
G+ + + T+C D+D D Q PC CK
Sbjct: 1834 RGFQASADQTLC---MDID-ECDRQ-PCGNGTCK 1862
Score = 39.5 bits (88), Expect = 0.046
Identities = 54/216 (25%), Positives = 80/216 (37%), Gaps = 34/216 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPG-SQTSDGQTCRTACSANPCFGG--RVPC-QDLPD--GRY 71
+CV C +T+ FRC+ G + +DG+ C + C+G + C + P +
Sbjct: 581 ICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKS 640
Query: 72 QCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
+C C + HG G C + + FQ + C S G DGR
Sbjct: 641 EC-CCANPDHGFGEPCQLCPAKNSAEFQAL----------CSS-GLGITTDGRDINECAL 688
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLVSCRNEE 189
+ C + ++ Y C C GY+ +G C D+DEC L D C+N
Sbjct: 689 DPEVCANG---VCENLRGSYRCV-CNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSP 744
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDEC 225
W+ T E C DVDEC
Sbjct: 745 GSYSCSCPPGFHF----WQDT------EICKDVDEC 770
Score = 37.5 bits (83), Expect = 0.19
Identities = 86/345 (24%), Positives = 114/345 (33%), Gaps = 67/345 (19%)
Query: 8 DAGSMVTPFKLCVGERCVDTDQGFRCERCPGSQTS-DGQTC--------RTACSANPCFG 58
D + LC RCV+T+ F+C G + S DG+ C T C C
Sbjct: 489 DVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLN 548
Query: 59 --GRVPCQD------LPDGRY-----QC---GKCPSGFHGNGVECYRISCRANTCF--QG 100
G C P G Y +C G C +G N +R C G
Sbjct: 549 EDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDG 608
Query: 101 VSCEETQYGPKC------GSCPTGYVGDGRQCQHVC-DAQKPCGRERRCMPKSTSPYYEC 153
C +T C GSC + G + + C + G + P S ++
Sbjct: 609 RVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQA 668
Query: 154 EGCPSGYQWNGYTCV--DMDECDLI-RPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGT 210
C SG G T D++EC L C + V C N + G
Sbjct: 669 L-CSSGL---GITTDGRDINECALDPEVCANGV-CENLRGSYRCVCNLGYEAGASG---- 719
Query: 211 GNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTT 270
+ C DVDECA C G C N+P GSY C G ++ T
Sbjct: 720 ------KDCTDVDECALNSLLCDNG-WCQNSP-----------GSYSCSCPPGFHFWQDT 761
Query: 271 RPCFDPDS-LVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
C D D L C CR N + KC + +GT C
Sbjct: 762 EICKDVDECLSSPCVSGVCR--NLAGSYTCKCGPGSRLDPSGTFC 804
Score = 35.5 bits (78), Expect = 0.75
Identities = 35/110 (31%), Positives = 50/110 (45%), Gaps = 14/110 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPG-SQTSDGQTCRTA--CS-ANPCFGGRVPCQDLPDGRYQC 73
LC +C++ G+RCE G T D + C+ C+ N C G C++LP G ++C
Sbjct: 1372 LCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFG--SCENLP-GMFRC 1428
Query: 74 GKCPSGFH--GNGVECYRISCRAN--TCFQGVSCEETQYGPKCGSCPTGY 119
C G+ G C I+ A+ C GV C T C SCP +
Sbjct: 1429 -ICNGGYELDRGGGNCTDINECADPVNCINGV-CINTPGSYLC-SCPQDF 1475
Score = 33.5 bits (73), Expect = 3.0
Identities = 29/93 (31%), Positives = 36/93 (38%), Gaps = 17/93 (18%)
Query: 216 REHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFD 275
R C+DVDEC + C G CVN P G+Y C G T + C D
Sbjct: 444 RGECIDVDECTS--SPCHHGD-CVNIP-----------GTYHCRCYPGFQATPTRQACVD 489
Query: 276 PDSLVKRCDPSYCRRFNAVCGFGQ-KCVCNTGW 307
D + C V G +CVCN G+
Sbjct: 490 VDECI--VSGGLCHLGRCVNTEGSFQCVCNAGF 520
Score = 31.9 bits (69), Expect = 9.2
Identities = 26/81 (32%), Positives = 31/81 (38%), Gaps = 8/81 (9%)
Query: 1 MHAGSMGDAGSMVTPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPC--- 56
+H G+ D LC G CV+ F C RCP G + SD A C
Sbjct: 240 IHTGACQDVDECQAVPGLCQGGSCVNMVGSFHC-RCPVGHRLSDSSAACEDYRAGACFSV 298
Query: 57 -FGGRVPCQDLPDGRYQCGKC 76
FGGR C G Y +C
Sbjct: 299 LFGGR--CAGDLAGHYTRRQC 317
>AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 70.9 bits (166), Expect = 2e-11
Identities = 92/318 (28%), Positives = 123/318 (38%), Gaps = 50/318 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQ-TSDGQTCR--TACSANPCFGGRVPCQDLPDGRYQCG 74
LC G C +TD ++C+ PG + T+ G C CS + C ++ G +QC
Sbjct: 1081 LCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNV-IGAFQC- 1138
Query: 75 KCPSGFHG--NGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQHV 129
C +GF + C I+ CR V C T+ +C SC GY + DGR C V
Sbjct: 1139 SCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRC-SCGQGYSLMPDGRACADV 1197
Query: 130 --CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSC 185
C+ + C + + C C G+ + TCVD+DECDL C
Sbjct: 1198 DECEENPRVCDQGHC--TNMPGGHRCL-CYDGFMATPDMRTCVDVDECDLNPHICLHGDC 1254
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N + +G G C DVDEC G NC C+N P
Sbjct: 1255 ENTK-GSFVCHCQLGYMVRKGATG---------CSDVDECEVGGHNCDSHASCLNIP--- 1301
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK---RCDP-SYCRRFNAVCGFGQKC 301
GS+ C G +V C D D V RC P C V G +C
Sbjct: 1302 --------GSFSCRCLPG--WVGDGFECHDLDECVSQEHRCSPRGDCLN---VPG-SYRC 1347
Query: 302 VCNTGWTGNGTVCGLDRD 319
C G+ G+G C DRD
Sbjct: 1348 TCRQGFAGDGFFCE-DRD 1364
Score = 62.9 bits (146), Expect = 4e-09
Identities = 92/315 (29%), Positives = 117/315 (37%), Gaps = 53/315 (16%)
Query: 21 GERCVDTDQGF---RCE--RCPGSQTSDGQTCRTACSANPCFGGRVPCQDLP-DGRYQCG 74
G RC DT Q F R E +C + + R CS P G PC+ P +G
Sbjct: 2006 GHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQ 2065
Query: 75 K-CPSGFHGN--GVECYRIS---CRAN--TCFQGVSCEETQYGPKCGSCPTGYVGD--GR 124
+ CP G HG G + R C N C GV C T +C CP GY D G
Sbjct: 2066 ELCPFG-HGAVPGPDDSREDVNECAENPGVCTNGV-CVNTDGSFRC-ECPFGYSLDFTGI 2122
Query: 125 QCQHV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN-GYTCVDMDECDLIRPCDD 181
C C PCG + C + +EC C G++ TC D+DEC L P
Sbjct: 2123 NCVDTDECSVGHPCG-QGTCT--NVIGGFEC-ACADGFEPGLMMTCEDIDECSL-NPLLC 2177
Query: 182 LVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC-PRGRLCVN 240
C N E G C DVDECADG+ +C RG C N
Sbjct: 2178 AFRCHNTEGSYLCTCPAGYTLREDG----------AMCRDVDECADGQQDCHARGMECKN 2227
Query: 241 TPQYPSNPVSSLQGSYICV-PCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ 299
L G++ CV P G + C D + P C V G
Sbjct: 2228 -----------LIGTFACVCPPGMRPLPGSGEGCTDDNEC--HAQPDLCVNGRCVNTAGS 2274
Query: 300 -KCVCNTGWTGNGTV 313
+C C+ G+ + T+
Sbjct: 2275 FRCDCDEGFQPSPTL 2289
Score = 61.3 bits (142), Expect = 1e-08
Identities = 64/231 (27%), Positives = 85/231 (36%), Gaps = 33/231 (14%)
Query: 24 CVDTDQGFRCERCPGSQT--SDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCGKCPS 78
C +T F C CP DG+TC+ + C + CQ L G + C +CP
Sbjct: 2420 CKNTKGSFLCS-CPRGYLLEEDGRTCK---DLDECTSRQHNCQFLCVNTVGAFTC-RCPP 2474
Query: 79 GFHGNGVECY---RISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQHVCDAQ 133
GF + C+ S + C C T +C C G+ V G C+ V +
Sbjct: 2475 GFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRC-ECHQGFTLVSSGHGCEDVNECD 2533
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGY--TCVDMDECDLIRPCDDLVSCRNEEXX 191
P + C + Y C CP G+ + CVD +EC L P SCRN
Sbjct: 2534 GPHRCQHGCQNQLGG--YRCS-CPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGG 2590
Query: 192 XXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G ++ C DVDECA R C C NTP
Sbjct: 2591 FRCVCPS----------GFDFDQALGGCQDVDECAGRRGPCSYS--CANTP 2629
Score = 57.6 bits (133), Expect = 2e-07
Identities = 79/293 (26%), Positives = 107/293 (36%), Gaps = 51/293 (17%)
Query: 17 KLCVGERCVDTDQGFRCERCPGSQ-TSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQC 73
++C C + G RC G T D +TC C NP C++ G + C
Sbjct: 1205 RVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTK-GSFVC 1263
Query: 74 GKCPSGF--HGNGVECYRIS-CRA--NTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQH 128
C G+ C + C + C SC C C G+VGDG +C
Sbjct: 1264 -HCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSC-RCLPGWVGDGFECH- 1320
Query: 129 VCDAQKPCGRERRCMPK----STSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDLV 183
D + +E RC P+ + Y C C G+ +G+ C D DEC + + CD+
Sbjct: 1321 --DLDECVSQEHRCSPRGDCLNVPGSYRCT-CRQGFAGDGFFCEDRDECAENVDLCDN-G 1376
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQ 243
C N G+ T + R C DVDECA G C G C N P
Sbjct: 1377 QCLN-------APGGYRCECEMGFDPTEDHRA---CQDVDECAQGNL-CAFGS-CENLP- 1423
Query: 244 YPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRC-DPSYCRRFNAVC 295
G + C+ GG+ C D + C DP C N VC
Sbjct: 1424 ----------GMFRCICNGGYELDRGGGNCTD----INECADPVNC--INGVC 1460
Score = 55.6 bits (128), Expect = 7e-07
Identities = 66/239 (27%), Positives = 94/239 (39%), Gaps = 36/239 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACS-ANPC-FGGR-----VPCQDLPDGR 70
+C+ C +T F C G G T CS + C GG C ++P G
Sbjct: 1248 ICLHGDCENTKGSFVCHCQLGYMVRKGAT---GCSDVDECEVGGHNCDSHASCLNIP-GS 1303
Query: 71 YQCGKCPSGFHGNGVECYRIS-C--RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ 127
+ C +C G+ G+G EC+ + C + + C C +C +C G+ GDG C+
Sbjct: 1304 FSC-RCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRC-TCRQGFAGDGFFCE 1361
Query: 128 H--VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLV 183
C +C+ + Y CE C G+ + C D+DEC C
Sbjct: 1362 DRDECAENVDLCDNGQCL--NAPGGYRCE-CEMGFDPTEDHRACQDVDECAQGNLCA-FG 1417
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
SC N RG GN C D++ECAD NC G +C+NTP
Sbjct: 1418 SCENLPGMFRCICNGGYELD----RGGGN------CTDINECAD-PVNCING-VCINTP 1464
Score = 55.2 bits (127), Expect = 9e-07
Identities = 88/361 (24%), Positives = 128/361 (35%), Gaps = 51/361 (14%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQ----TCRTACSANPCFGGRVPCQDLPDGRYQC 73
LC C +T F C C G D Q T C +P G+ C + P G ++C
Sbjct: 996 LCTHGTCRNTVGSFHCA-CAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTP-GSFEC 1053
Query: 74 GKCPSGFHGNGV---ECYRIS--CRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQC 126
+C G+ + C + R +G +C T KC CP G+ G C
Sbjct: 1054 -ECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKC-QCPPGHELTAKGTAC 1111
Query: 127 QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRP-CDDLV 183
+ + + G + ++C C +G+Q + CVD++EC + CD V
Sbjct: 1112 EDIDECSLSDGLCPHGQCVNVIGAFQCS-CHAGFQSTPDRQGCVDINECRVQNGGCD--V 1168
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRRE--------HCVDVDE-----CADGRA 230
C N E G + E HC ++ C DG
Sbjct: 1169 HCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFM 1228
Query: 231 NCPRGRLCVNTPQYPSNP-------VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLV--- 280
P R CV+ + NP + +GS++C G+ C D D
Sbjct: 1229 ATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGG 1288
Query: 281 KRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRCKKDNC 340
CD S+ N F C C GW G+G C DLD ++ C+ PR N
Sbjct: 1289 HNCD-SHASCLNIPGSF--SCRCLPGWVGDGFEC---HDLDECVSQEHRCS-PRGDCLNV 1341
Query: 341 P 341
P
Sbjct: 1342 P 1342
Score = 54.8 bits (126), Expect = 1e-06
Identities = 77/300 (25%), Positives = 107/300 (35%), Gaps = 51/300 (17%)
Query: 24 CVDTDQGFRCERCPG-SQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C++T+ +RC G S DG+ C C NP + C ++P G ++C C GF
Sbjct: 1170 CINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGG-HRC-LCYDGF 1227
Query: 81 HGNG-----VECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY-VGDGRQ-CQHVCDAQ 133
V+ + C G CE T+ C C GY V G C V + +
Sbjct: 1228 MATPDMRTCVDVDECDLNPHICLHG-DCENTKGSFVC-HCQLGYMVRKGATGCSDVDECE 1285
Query: 134 ---KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDLVSCRNEE 189
C C+ S + C C G+ +G+ C D+DEC C C N
Sbjct: 1286 VGGHNCDSHASCLNIPGS--FSCR-CLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVP 1342
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPV 249
QG+ G G C D DECA+ C G+ C+N P
Sbjct: 1343 GSYRCTCR-------QGFAGDGF-----FCEDRDECAENVDLCDNGQ-CLNAP------- 1382
Query: 250 SSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK--RCDPSYCRRFNAVCGFGQKCVCNTGW 307
G Y C G R C D D + C C + +C+CN G+
Sbjct: 1383 ----GGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMF----RCICNGGY 1434
Score = 54.8 bits (126), Expect = 1e-06
Identities = 90/342 (26%), Positives = 126/342 (36%), Gaps = 67/342 (19%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGG--RVPCQDLPDG-----R 70
LCV RCV+T FRC+ G Q S T PCF + C+ L R
Sbjct: 2262 LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTR 2321
Query: 71 YQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCP--TGYVGDGRQCQH 128
+C C G G G C + ++ + CP +GY +GR
Sbjct: 2322 AEC--CCGGGRGWGPRCELCPLPGTSAYRKL-------------CPHGSGYTAEGRDVDE 2366
Query: 129 VCDAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLI-RPCDDLVSC 185
C C+ S + C C +GY TC+DMDEC + +PC L C
Sbjct: 2367 -CRMLAHLCAHGECINSLGS--FRCH-CQAGYTPDATATTCLDMDECSQVPKPCTFL--C 2420
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
+N + RG E C D+DEC + NC LCVNT
Sbjct: 2421 KNTKGSFLCSCP----------RGYLLEEDGRTCKDLDECTSRQHNCQ--FLCVNT---- 2464
Query: 246 SNPVSSLQGSYIC-VPCGGHYYVNTTRPCFDPDSLVKRCDP--SYCRRFNAVCGFGQKCV 302
G++ C P G + + CFD D + P ++ N F +C
Sbjct: 2465 -------VGAFTCRCPPG---FTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSF--RCE 2512
Query: 303 CNTGWT--GNGTVCGLDRDLDGHPDEQLPC-NEPRCKKDNCP 341
C+ G+T +G C + DG Q C N+ + +CP
Sbjct: 2513 CHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCP 2554
Score = 48.4 bits (110), Expect = 1e-04
Identities = 56/229 (24%), Positives = 87/229 (37%), Gaps = 29/229 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTC--RTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
C++ +RC+ G + S G C R C P C D +G Y C C GF
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMD-TEGSYMC-LCHRGFQ 1837
Query: 82 GNGVE--CYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGR 138
+ + C I C C G +C+ C P V C + G+
Sbjct: 1838 ASADQTLCMDIDECDRQPCGNG-TCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1896
Query: 139 ERR---CMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSCRNEEXXXX 193
R C+ +T+ + C C G++ +G CVD +EC + +C+N E
Sbjct: 1897 VCRFGHCL--NTAGSFHCL-CQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFR 1953
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G + + +HC+D+DEC++ C G C N+P
Sbjct: 1954 CIC------------PPGFQVQSDHCIDIDECSEEPNLCLFG-TCTNSP 1989
Score = 48.0 bits (109), Expect = 1e-04
Identities = 53/186 (28%), Positives = 77/186 (41%), Gaps = 26/186 (13%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSD--GQTCRT-ACSANPCFGGRVPCQDLPDGRYQCG 74
LC+ RC+ T +RCE C T D G+ C+++PC G C ++P G Y C
Sbjct: 418 LCLNGRCLPTPSSYRCE-CNVGYTQDVRGECIDVDECTSSPCHHG--DCVNIP-GTYHC- 472
Query: 75 KCPSGFHGNGVE--CYRI-SC--RANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQC- 126
+C GF C + C C G C T+ +C C G+ DG+ C
Sbjct: 473 RCYPGFQATPTRQACVDVDECIVSGGLCHLG-RCVNTEGSFQC-VCNAGFELSPDGKNCV 530
Query: 127 -QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLV 183
+ C C C+ + S + C C G+ G+ C+D+DEC C +
Sbjct: 531 DHNECATSTMC-VNGVCLNEDGS--FSCL-CKPGFLLAPGGHYCMDIDECQTPGICVN-G 585
Query: 184 SCRNEE 189
C N E
Sbjct: 586 HCTNTE 591
Score = 47.2 bits (107), Expect = 2e-04
Identities = 85/324 (26%), Positives = 113/324 (34%), Gaps = 57/324 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKC- 76
LC+ C ++ F+C PG SD + + CF R Q R++ GKC
Sbjct: 1979 LCLFGTCTNSPGSFQCLCPPGFVLSD--------NGHRCFDTR---QSFCFTRFEAGKCS 2027
Query: 77 -PSGFHGNGVECYRISCRANTCFQGVSCEET-QYGPKCGS--CPTGYVG-----DGRQCQ 127
P F+ C S R + G CE Q G CP G+ D R+
Sbjct: 2028 VPKAFNTTKTRCC-CSKRPGEGW-GDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDV 2085
Query: 128 HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLVSC 185
+ C A+ P G + +T + CE CP GY + G CVD DEC + PC +C
Sbjct: 2086 NEC-AENP-GVCTNGVCVNTDGSFRCE-CPFGYSLDFTGINCVDTDECSVGHPCGQ-GTC 2141
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N G T C D+DEC+ C C NT
Sbjct: 2142 TN---VIGGFECACADGFEPGLMMT--------CEDIDECSLNPLLC--AFRCHNT---- 2184
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCN 304
+GSY+C G+ C D D + R G CVC
Sbjct: 2185 -------EGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCP 2237
Query: 305 TGW---TGNGTVCGLDRDLDGHPD 325
G G+G C D + PD
Sbjct: 2238 PGMRPLPGSGEGCTDDNECHAQPD 2261
Score = 44.4 bits (100), Expect = 0.002
Identities = 45/168 (26%), Positives = 67/168 (39%), Gaps = 21/168 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQT-CRTA--CSANPCFGGRVPCQDLPDGRYQCG 74
+C C+DT+ + C G Q S QT C C PC G C+++ G Y C
Sbjct: 1815 VCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGT--CKNII-GSYNC- 1870
Query: 75 KCPSGF----HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQH 128
C GF +G+ V+ + + C T C C G+ DG+ C
Sbjct: 1871 LCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHC-LCQDGFELTADGKNCVD 1929
Query: 129 VCDAQKPCGRERRCMP---KSTSPYYECEGCPSGYQWNGYTCVDMDEC 173
+ G C+P ++ + C CP G+Q C+D+DEC
Sbjct: 1930 TNECLSLAGT---CLPGTCQNLEGSFRCI-CPPGFQVQSDHCIDIDEC 1973
Score = 43.6 bits (98), Expect = 0.003
Identities = 66/259 (25%), Positives = 96/259 (37%), Gaps = 46/259 (17%)
Query: 69 GRYQCGKCPSGFHGNGV--ECYRIS-C--RANTCFQGVSCEETQYGPKCGSCPTGY-VGD 122
G ++C +CP+GF+ N + C + C R + C Q C +C C GY +
Sbjct: 1742 GSFRC-ECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC-KCTRGYKLSP 1799
Query: 123 GRQC--QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLIRP 178
G C ++ C CM T Y C C G+Q + C+D+DECD +P
Sbjct: 1800 GGACVGRNECREIPNVCSHGDCM--DTEGSYMCL-CHRGFQASADQTLCMDIDECDR-QP 1855
Query: 179 CDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLC 238
C + +C+N G+ T N CVD DEC R C
Sbjct: 1856 CGN-GTCKN-------IIGSYNCLCFPGFVVTHN----GDCVDFDECTTLVGQVCRFGHC 1903
Query: 239 VNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPD---SLVKRCDPSYCRRFNAVC 295
+NT GS+ C+ G + C D + SL C P C+
Sbjct: 1904 LNT-----------AGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEG-- 1950
Query: 296 GFGQKCVCNTGWTGNGTVC 314
+C+C G+ C
Sbjct: 1951 --SFRCICPPGFQVQSDHC 1967
Score = 42.7 bits (96), Expect = 0.005
Identities = 84/334 (25%), Positives = 122/334 (36%), Gaps = 59/334 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDG-QTCRTA--CSANPCFGGRVPCQDLPDGRYQCG 74
LC G CV+T F+CE PG S+ + C CS + G C + G Y C
Sbjct: 1573 LCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTL-GNYTC- 1630
Query: 75 KCPSGFH--GNGVECYRISCRANTCFQ---GVSCEETQYGPKCGSCPTGYVGDGRQCQHV 129
CP+ + G C + R + CF+ G E + C Y G+
Sbjct: 1631 VCPAEYLQVNGGNNC--MDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSY-NIGQAWNRP 1687
Query: 130 CDAQKPCGRERRCMPKSTSPYYE--CEGCPSGYQWNGYTC--VDMDECDLIRPCDDLVSC 185
C+A C P SP Y+ C G+ + +T +D+DEC I C
Sbjct: 1688 CEA---------C-PTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANGIC 1737
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N+ + G C DVDEC + C + C+N P
Sbjct: 1738 INQ----------IGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIP--- 1784
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCN 304
GSY C C Y ++ C + R P+ C + + G C+C+
Sbjct: 1785 --------GSYRC-KCTRGYKLSPGGACVGRNEC--REIPNVCSHGDCMDTEGSYMCLCH 1833
Query: 305 TGW--TGNGTVCGLDRDLDGHPDEQLPCNEPRCK 336
G+ + + T+C D+D D Q PC CK
Sbjct: 1834 RGFQASADQTLC---MDID-ECDRQ-PCGNGTCK 1862
Score = 39.5 bits (88), Expect = 0.046
Identities = 54/216 (25%), Positives = 80/216 (37%), Gaps = 34/216 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPG-SQTSDGQTCRTACSANPCFGG--RVPC-QDLPD--GRY 71
+CV C +T+ FRC+ G + +DG+ C + C+G + C + P +
Sbjct: 581 ICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKS 640
Query: 72 QCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
+C C + HG G C + + FQ + C S G DGR
Sbjct: 641 EC-CCANPDHGFGEPCQLCPAKNSAEFQAL----------CSS-GLGITTDGRDINECAL 688
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLVSCRNEE 189
+ C + ++ Y C C GY+ +G C D+DEC L D C+N
Sbjct: 689 DPEVCANG---VCENLRGSYRCV-CNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSP 744
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDEC 225
W+ T E C DVDEC
Sbjct: 745 GSYSCSCPPGFHF----WQDT------EICKDVDEC 770
Score = 37.5 bits (83), Expect = 0.19
Identities = 86/345 (24%), Positives = 114/345 (33%), Gaps = 67/345 (19%)
Query: 8 DAGSMVTPFKLCVGERCVDTDQGFRCERCPGSQTS-DGQTC--------RTACSANPCFG 58
D + LC RCV+T+ F+C G + S DG+ C T C C
Sbjct: 489 DVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLN 548
Query: 59 --GRVPCQD------LPDGRY-----QC---GKCPSGFHGNGVECYRISCRANTCF--QG 100
G C P G Y +C G C +G N +R C G
Sbjct: 549 EDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDG 608
Query: 101 VSCEETQYGPKC------GSCPTGYVGDGRQCQHVC-DAQKPCGRERRCMPKSTSPYYEC 153
C +T C GSC + G + + C + G + P S ++
Sbjct: 609 RVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQA 668
Query: 154 EGCPSGYQWNGYTCV--DMDECDLI-RPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGT 210
C SG G T D++EC L C + V C N + G
Sbjct: 669 L-CSSGL---GITTDGRDINECALDPEVCANGV-CENLRGSYRCVCNLGYEAGASG---- 719
Query: 211 GNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTT 270
+ C DVDECA C G C N+P GSY C G ++ T
Sbjct: 720 ------KDCTDVDECALNSLLCDNG-WCQNSP-----------GSYSCSCPPGFHFWQDT 761
Query: 271 RPCFDPDS-LVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
C D D L C CR N + KC + +GT C
Sbjct: 762 EICKDVDECLSSPCVSGVCR--NLAGSYTCKCGPGSRLDPSGTFC 804
Score = 35.5 bits (78), Expect = 0.75
Identities = 35/110 (31%), Positives = 50/110 (45%), Gaps = 14/110 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPG-SQTSDGQTCRTA--CS-ANPCFGGRVPCQDLPDGRYQC 73
LC +C++ G+RCE G T D + C+ C+ N C G C++LP G ++C
Sbjct: 1372 LCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFG--SCENLP-GMFRC 1428
Query: 74 GKCPSGFH--GNGVECYRISCRAN--TCFQGVSCEETQYGPKCGSCPTGY 119
C G+ G C I+ A+ C GV C T C SCP +
Sbjct: 1429 -ICNGGYELDRGGGNCTDINECADPVNCINGV-CINTPGSYLC-SCPQDF 1475
Score = 33.5 bits (73), Expect = 3.0
Identities = 29/93 (31%), Positives = 36/93 (38%), Gaps = 17/93 (18%)
Query: 216 REHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFD 275
R C+DVDEC + C G CVN P G+Y C G T + C D
Sbjct: 444 RGECIDVDECTS--SPCHHGD-CVNIP-----------GTYHCRCYPGFQATPTRQACVD 489
Query: 276 PDSLVKRCDPSYCRRFNAVCGFGQ-KCVCNTGW 307
D + C V G +CVCN G+
Sbjct: 490 VDECI--VSGGLCHLGRCVNTEGSFQCVCNAGF 520
Score = 31.9 bits (69), Expect = 9.2
Identities = 26/81 (32%), Positives = 31/81 (38%), Gaps = 8/81 (9%)
Query: 1 MHAGSMGDAGSMVTPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPC--- 56
+H G+ D LC G CV+ F C RCP G + SD A C
Sbjct: 240 IHTGACQDVDECQAVPGLCQGGSCVNMVGSFHC-RCPVGHRLSDSSAACEDYRAGACFSV 298
Query: 57 -FGGRVPCQDLPDGRYQCGKC 76
FGGR C G Y +C
Sbjct: 299 LFGGR--CAGDLAGHYTRRQC 317
>AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 70.9 bits (166), Expect = 2e-11
Identities = 92/318 (28%), Positives = 123/318 (38%), Gaps = 50/318 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQ-TSDGQTCR--TACSANPCFGGRVPCQDLPDGRYQCG 74
LC G C +TD ++C+ PG + T+ G C CS + C ++ G +QC
Sbjct: 1081 LCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNV-IGAFQC- 1138
Query: 75 KCPSGFHG--NGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQHV 129
C +GF + C I+ CR V C T+ +C SC GY + DGR C V
Sbjct: 1139 SCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRC-SCGQGYSLMPDGRACADV 1197
Query: 130 --CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSC 185
C+ + C + + C C G+ + TCVD+DECDL C
Sbjct: 1198 DECEENPRVCDQGHC--TNMPGGHRCL-CYDGFMATPDMRTCVDVDECDLNPHICLHGDC 1254
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N + +G G C DVDEC G NC C+N P
Sbjct: 1255 ENTK-GSFVCHCQLGYMVRKGATG---------CSDVDECEVGGHNCDSHASCLNIP--- 1301
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK---RCDP-SYCRRFNAVCGFGQKC 301
GS+ C G +V C D D V RC P C V G +C
Sbjct: 1302 --------GSFSCRCLPG--WVGDGFECHDLDECVSQEHRCSPRGDCLN---VPG-SYRC 1347
Query: 302 VCNTGWTGNGTVCGLDRD 319
C G+ G+G C DRD
Sbjct: 1348 TCRQGFAGDGFFCE-DRD 1364
Score = 62.9 bits (146), Expect = 4e-09
Identities = 92/315 (29%), Positives = 117/315 (37%), Gaps = 53/315 (16%)
Query: 21 GERCVDTDQGF---RCE--RCPGSQTSDGQTCRTACSANPCFGGRVPCQDLP-DGRYQCG 74
G RC DT Q F R E +C + + R CS P G PC+ P +G
Sbjct: 2006 GHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQ 2065
Query: 75 K-CPSGFHGN--GVECYRIS---CRAN--TCFQGVSCEETQYGPKCGSCPTGYVGD--GR 124
+ CP G HG G + R C N C GV C T +C CP GY D G
Sbjct: 2066 ELCPFG-HGAVPGPDDSREDVNECAENPGVCTNGV-CVNTDGSFRC-ECPFGYSLDFTGI 2122
Query: 125 QCQHV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN-GYTCVDMDECDLIRPCDD 181
C C PCG + C + +EC C G++ TC D+DEC L P
Sbjct: 2123 NCVDTDECSVGHPCG-QGTCT--NVIGGFEC-ACADGFEPGLMMTCEDIDECSL-NPLLC 2177
Query: 182 LVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC-PRGRLCVN 240
C N E G C DVDECADG+ +C RG C N
Sbjct: 2178 AFRCHNTEGSYLCTCPAGYTLREDG----------AMCRDVDECADGQQDCHARGMECKN 2227
Query: 241 TPQYPSNPVSSLQGSYICV-PCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ 299
L G++ CV P G + C D + P C V G
Sbjct: 2228 -----------LIGTFACVCPPGMRPLPGSGEGCTDDNEC--HAQPDLCVNGRCVNTAGS 2274
Query: 300 -KCVCNTGWTGNGTV 313
+C C+ G+ + T+
Sbjct: 2275 FRCDCDEGFQPSPTL 2289
Score = 61.3 bits (142), Expect = 1e-08
Identities = 64/231 (27%), Positives = 85/231 (36%), Gaps = 33/231 (14%)
Query: 24 CVDTDQGFRCERCPGSQT--SDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCGKCPS 78
C +T F C CP DG+TC+ + C + CQ L G + C +CP
Sbjct: 2420 CKNTKGSFLCS-CPRGYLLEEDGRTCK---DLDECTSRQHNCQFLCVNTVGAFTC-RCPP 2474
Query: 79 GFHGNGVECY---RISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQHVCDAQ 133
GF + C+ S + C C T +C C G+ V G C+ V +
Sbjct: 2475 GFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRC-ECHQGFTLVSSGHGCEDVNECD 2533
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGY--TCVDMDECDLIRPCDDLVSCRNEEXX 191
P + C + Y C CP G+ + CVD +EC L P SCRN
Sbjct: 2534 GPHRCQHGCQNQLGG--YRCS-CPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGG 2590
Query: 192 XXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G ++ C DVDECA R C C NTP
Sbjct: 2591 FRCVCPS----------GFDFDQALGGCQDVDECAGRRGPCSYS--CANTP 2629
Score = 57.6 bits (133), Expect = 2e-07
Identities = 79/293 (26%), Positives = 107/293 (36%), Gaps = 51/293 (17%)
Query: 17 KLCVGERCVDTDQGFRCERCPGSQ-TSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQC 73
++C C + G RC G T D +TC C NP C++ G + C
Sbjct: 1205 RVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTK-GSFVC 1263
Query: 74 GKCPSGF--HGNGVECYRIS-CRA--NTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQH 128
C G+ C + C + C SC C C G+VGDG +C
Sbjct: 1264 -HCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSC-RCLPGWVGDGFECH- 1320
Query: 129 VCDAQKPCGRERRCMPK----STSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDLV 183
D + +E RC P+ + Y C C G+ +G+ C D DEC + + CD+
Sbjct: 1321 --DLDECVSQEHRCSPRGDCLNVPGSYRCT-CRQGFAGDGFFCEDRDECAENVDLCDN-G 1376
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQ 243
C N G+ T + R C DVDECA G C G C N P
Sbjct: 1377 QCLN-------APGGYRCECEMGFDPTEDHRA---CQDVDECAQGNL-CAFGS-CENLP- 1423
Query: 244 YPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRC-DPSYCRRFNAVC 295
G + C+ GG+ C D + C DP C N VC
Sbjct: 1424 ----------GMFRCICNGGYELDRGGGNCTD----INECADPVNC--INGVC 1460
Score = 55.6 bits (128), Expect = 7e-07
Identities = 66/239 (27%), Positives = 94/239 (39%), Gaps = 36/239 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACS-ANPC-FGGR-----VPCQDLPDGR 70
+C+ C +T F C G G T CS + C GG C ++P G
Sbjct: 1248 ICLHGDCENTKGSFVCHCQLGYMVRKGAT---GCSDVDECEVGGHNCDSHASCLNIP-GS 1303
Query: 71 YQCGKCPSGFHGNGVECYRIS-C--RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ 127
+ C +C G+ G+G EC+ + C + + C C +C +C G+ GDG C+
Sbjct: 1304 FSC-RCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRC-TCRQGFAGDGFFCE 1361
Query: 128 H--VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLV 183
C +C+ + Y CE C G+ + C D+DEC C
Sbjct: 1362 DRDECAENVDLCDNGQCL--NAPGGYRCE-CEMGFDPTEDHRACQDVDECAQGNLCA-FG 1417
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
SC N RG GN C D++ECAD NC G +C+NTP
Sbjct: 1418 SCENLPGMFRCICNGGYELD----RGGGN------CTDINECAD-PVNCING-VCINTP 1464
Score = 55.2 bits (127), Expect = 9e-07
Identities = 88/361 (24%), Positives = 128/361 (35%), Gaps = 51/361 (14%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQ----TCRTACSANPCFGGRVPCQDLPDGRYQC 73
LC C +T F C C G D Q T C +P G+ C + P G ++C
Sbjct: 996 LCTHGTCRNTVGSFHCA-CAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTP-GSFEC 1053
Query: 74 GKCPSGFHGNGV---ECYRIS--CRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQC 126
+C G+ + C + R +G +C T KC CP G+ G C
Sbjct: 1054 -ECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKC-QCPPGHELTAKGTAC 1111
Query: 127 QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRP-CDDLV 183
+ + + G + ++C C +G+Q + CVD++EC + CD V
Sbjct: 1112 EDIDECSLSDGLCPHGQCVNVIGAFQCS-CHAGFQSTPDRQGCVDINECRVQNGGCD--V 1168
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRRE--------HCVDVDE-----CADGRA 230
C N E G + E HC ++ C DG
Sbjct: 1169 HCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFM 1228
Query: 231 NCPRGRLCVNTPQYPSNP-------VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLV--- 280
P R CV+ + NP + +GS++C G+ C D D
Sbjct: 1229 ATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGG 1288
Query: 281 KRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRCKKDNC 340
CD S+ N F C C GW G+G C DLD ++ C+ PR N
Sbjct: 1289 HNCD-SHASCLNIPGSF--SCRCLPGWVGDGFEC---HDLDECVSQEHRCS-PRGDCLNV 1341
Query: 341 P 341
P
Sbjct: 1342 P 1342
Score = 54.8 bits (126), Expect = 1e-06
Identities = 77/300 (25%), Positives = 107/300 (35%), Gaps = 51/300 (17%)
Query: 24 CVDTDQGFRCERCPG-SQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C++T+ +RC G S DG+ C C NP + C ++P G ++C C GF
Sbjct: 1170 CINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGG-HRC-LCYDGF 1227
Query: 81 HGNG-----VECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY-VGDGRQ-CQHVCDAQ 133
V+ + C G CE T+ C C GY V G C V + +
Sbjct: 1228 MATPDMRTCVDVDECDLNPHICLHG-DCENTKGSFVC-HCQLGYMVRKGATGCSDVDECE 1285
Query: 134 ---KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDLVSCRNEE 189
C C+ S + C C G+ +G+ C D+DEC C C N
Sbjct: 1286 VGGHNCDSHASCLNIPGS--FSCR-CLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVP 1342
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPV 249
QG+ G G C D DECA+ C G+ C+N P
Sbjct: 1343 GSYRCTCR-------QGFAGDGF-----FCEDRDECAENVDLCDNGQ-CLNAP------- 1382
Query: 250 SSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK--RCDPSYCRRFNAVCGFGQKCVCNTGW 307
G Y C G R C D D + C C + +C+CN G+
Sbjct: 1383 ----GGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMF----RCICNGGY 1434
Score = 54.8 bits (126), Expect = 1e-06
Identities = 90/342 (26%), Positives = 126/342 (36%), Gaps = 67/342 (19%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGG--RVPCQDLPDG-----R 70
LCV RCV+T FRC+ G Q S T PCF + C+ L R
Sbjct: 2262 LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTR 2321
Query: 71 YQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCP--TGYVGDGRQCQH 128
+C C G G G C + ++ + CP +GY +GR
Sbjct: 2322 AEC--CCGGGRGWGPRCELCPLPGTSAYRKL-------------CPHGSGYTAEGRDVDE 2366
Query: 129 VCDAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLI-RPCDDLVSC 185
C C+ S + C C +GY TC+DMDEC + +PC L C
Sbjct: 2367 -CRMLAHLCAHGECINSLGS--FRCH-CQAGYTPDATATTCLDMDECSQVPKPCTFL--C 2420
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
+N + RG E C D+DEC + NC LCVNT
Sbjct: 2421 KNTKGSFLCSCP----------RGYLLEEDGRTCKDLDECTSRQHNCQ--FLCVNT---- 2464
Query: 246 SNPVSSLQGSYIC-VPCGGHYYVNTTRPCFDPDSLVKRCDP--SYCRRFNAVCGFGQKCV 302
G++ C P G + + CFD D + P ++ N F +C
Sbjct: 2465 -------VGAFTCRCPPG---FTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSF--RCE 2512
Query: 303 CNTGWT--GNGTVCGLDRDLDGHPDEQLPC-NEPRCKKDNCP 341
C+ G+T +G C + DG Q C N+ + +CP
Sbjct: 2513 CHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCP 2554
Score = 48.4 bits (110), Expect = 1e-04
Identities = 56/229 (24%), Positives = 87/229 (37%), Gaps = 29/229 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTC--RTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
C++ +RC+ G + S G C R C P C D +G Y C C GF
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMD-TEGSYMC-LCHRGFQ 1837
Query: 82 GNGVE--CYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGR 138
+ + C I C C G +C+ C P V C + G+
Sbjct: 1838 ASADQTLCMDIDECDRQPCGNG-TCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1896
Query: 139 ERR---CMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSCRNEEXXXX 193
R C+ +T+ + C C G++ +G CVD +EC + +C+N E
Sbjct: 1897 VCRFGHCL--NTAGSFHCL-CQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFR 1953
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G + + +HC+D+DEC++ C G C N+P
Sbjct: 1954 CIC------------PPGFQVQSDHCIDIDECSEEPNLCLFG-TCTNSP 1989
Score = 48.0 bits (109), Expect = 1e-04
Identities = 53/186 (28%), Positives = 77/186 (41%), Gaps = 26/186 (13%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSD--GQTCRT-ACSANPCFGGRVPCQDLPDGRYQCG 74
LC+ RC+ T +RCE C T D G+ C+++PC G C ++P G Y C
Sbjct: 418 LCLNGRCLPTPSSYRCE-CNVGYTQDVRGECIDVDECTSSPCHHG--DCVNIP-GTYHC- 472
Query: 75 KCPSGFHGNGVE--CYRI-SC--RANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQC- 126
+C GF C + C C G C T+ +C C G+ DG+ C
Sbjct: 473 RCYPGFQATPTRQACVDVDECIVSGGLCHLG-RCVNTEGSFQC-VCNAGFELSPDGKNCV 530
Query: 127 -QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLV 183
+ C C C+ + S + C C G+ G+ C+D+DEC C +
Sbjct: 531 DHNECATSTMC-VNGVCLNEDGS--FSCL-CKPGFLLAPGGHYCMDIDECQTPGICVN-G 585
Query: 184 SCRNEE 189
C N E
Sbjct: 586 HCTNTE 591
Score = 47.2 bits (107), Expect = 2e-04
Identities = 85/324 (26%), Positives = 113/324 (34%), Gaps = 57/324 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKC- 76
LC+ C ++ F+C PG SD + + CF R Q R++ GKC
Sbjct: 1979 LCLFGTCTNSPGSFQCLCPPGFVLSD--------NGHRCFDTR---QSFCFTRFEAGKCS 2027
Query: 77 -PSGFHGNGVECYRISCRANTCFQGVSCEET-QYGPKCGS--CPTGYVG-----DGRQCQ 127
P F+ C S R + G CE Q G CP G+ D R+
Sbjct: 2028 VPKAFNTTKTRCC-CSKRPGEGW-GDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDV 2085
Query: 128 HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLVSC 185
+ C A+ P G + +T + CE CP GY + G CVD DEC + PC +C
Sbjct: 2086 NEC-AENP-GVCTNGVCVNTDGSFRCE-CPFGYSLDFTGINCVDTDECSVGHPCGQ-GTC 2141
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N G T C D+DEC+ C C NT
Sbjct: 2142 TN---VIGGFECACADGFEPGLMMT--------CEDIDECSLNPLLC--AFRCHNT---- 2184
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCN 304
+GSY+C G+ C D D + R G CVC
Sbjct: 2185 -------EGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCP 2237
Query: 305 TGW---TGNGTVCGLDRDLDGHPD 325
G G+G C D + PD
Sbjct: 2238 PGMRPLPGSGEGCTDDNECHAQPD 2261
Score = 44.4 bits (100), Expect = 0.002
Identities = 45/168 (26%), Positives = 67/168 (39%), Gaps = 21/168 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQT-CRTA--CSANPCFGGRVPCQDLPDGRYQCG 74
+C C+DT+ + C G Q S QT C C PC G C+++ G Y C
Sbjct: 1815 VCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGT--CKNII-GSYNC- 1870
Query: 75 KCPSGF----HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQH 128
C GF +G+ V+ + + C T C C G+ DG+ C
Sbjct: 1871 LCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHC-LCQDGFELTADGKNCVD 1929
Query: 129 VCDAQKPCGRERRCMP---KSTSPYYECEGCPSGYQWNGYTCVDMDEC 173
+ G C+P ++ + C CP G+Q C+D+DEC
Sbjct: 1930 TNECLSLAGT---CLPGTCQNLEGSFRCI-CPPGFQVQSDHCIDIDEC 1973
Score = 43.6 bits (98), Expect = 0.003
Identities = 66/259 (25%), Positives = 96/259 (37%), Gaps = 46/259 (17%)
Query: 69 GRYQCGKCPSGFHGNGV--ECYRIS-C--RANTCFQGVSCEETQYGPKCGSCPTGY-VGD 122
G ++C +CP+GF+ N + C + C R + C Q C +C C GY +
Sbjct: 1742 GSFRC-ECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC-KCTRGYKLSP 1799
Query: 123 GRQC--QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLIRP 178
G C ++ C CM T Y C C G+Q + C+D+DECD +P
Sbjct: 1800 GGACVGRNECREIPNVCSHGDCM--DTEGSYMCL-CHRGFQASADQTLCMDIDECDR-QP 1855
Query: 179 CDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLC 238
C + +C+N G+ T N CVD DEC R C
Sbjct: 1856 CGN-GTCKN-------IIGSYNCLCFPGFVVTHN----GDCVDFDECTTLVGQVCRFGHC 1903
Query: 239 VNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPD---SLVKRCDPSYCRRFNAVC 295
+NT GS+ C+ G + C D + SL C P C+
Sbjct: 1904 LNT-----------AGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEG-- 1950
Query: 296 GFGQKCVCNTGWTGNGTVC 314
+C+C G+ C
Sbjct: 1951 --SFRCICPPGFQVQSDHC 1967
Score = 42.7 bits (96), Expect = 0.005
Identities = 84/334 (25%), Positives = 122/334 (36%), Gaps = 59/334 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDG-QTCRTA--CSANPCFGGRVPCQDLPDGRYQCG 74
LC G CV+T F+CE PG S+ + C CS + G C + G Y C
Sbjct: 1573 LCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTL-GNYTC- 1630
Query: 75 KCPSGFH--GNGVECYRISCRANTCFQ---GVSCEETQYGPKCGSCPTGYVGDGRQCQHV 129
CP+ + G C + R + CF+ G E + C Y G+
Sbjct: 1631 VCPAEYLQVNGGNNC--MDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSY-NIGQAWNRP 1687
Query: 130 CDAQKPCGRERRCMPKSTSPYYE--CEGCPSGYQWNGYTC--VDMDECDLIRPCDDLVSC 185
C+A C P SP Y+ C G+ + +T +D+DEC I C
Sbjct: 1688 CEA---------C-PTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANGIC 1737
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N+ + G C DVDEC + C + C+N P
Sbjct: 1738 INQ----------IGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIP--- 1784
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCN 304
GSY C C Y ++ C + R P+ C + + G C+C+
Sbjct: 1785 --------GSYRC-KCTRGYKLSPGGACVGRNEC--REIPNVCSHGDCMDTEGSYMCLCH 1833
Query: 305 TGW--TGNGTVCGLDRDLDGHPDEQLPCNEPRCK 336
G+ + + T+C D+D D Q PC CK
Sbjct: 1834 RGFQASADQTLC---MDID-ECDRQ-PCGNGTCK 1862
Score = 39.5 bits (88), Expect = 0.046
Identities = 54/216 (25%), Positives = 80/216 (37%), Gaps = 34/216 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPG-SQTSDGQTCRTACSANPCFGG--RVPC-QDLPD--GRY 71
+CV C +T+ FRC+ G + +DG+ C + C+G + C + P +
Sbjct: 581 ICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKS 640
Query: 72 QCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
+C C + HG G C + + FQ + C S G DGR
Sbjct: 641 EC-CCANPDHGFGEPCQLCPAKNSAEFQAL----------CSS-GLGITTDGRDINECAL 688
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLVSCRNEE 189
+ C + ++ Y C C GY+ +G C D+DEC L D C+N
Sbjct: 689 DPEVCANG---VCENLRGSYRCV-CNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSP 744
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDEC 225
W+ T E C DVDEC
Sbjct: 745 GSYSCSCPPGFHF----WQDT------EICKDVDEC 770
Score = 37.5 bits (83), Expect = 0.19
Identities = 86/345 (24%), Positives = 114/345 (33%), Gaps = 67/345 (19%)
Query: 8 DAGSMVTPFKLCVGERCVDTDQGFRCERCPGSQTS-DGQTC--------RTACSANPCFG 58
D + LC RCV+T+ F+C G + S DG+ C T C C
Sbjct: 489 DVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLN 548
Query: 59 --GRVPCQD------LPDGRY-----QC---GKCPSGFHGNGVECYRISCRANTCF--QG 100
G C P G Y +C G C +G N +R C G
Sbjct: 549 EDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDG 608
Query: 101 VSCEETQYGPKC------GSCPTGYVGDGRQCQHVC-DAQKPCGRERRCMPKSTSPYYEC 153
C +T C GSC + G + + C + G + P S ++
Sbjct: 609 RVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQA 668
Query: 154 EGCPSGYQWNGYTCV--DMDECDLI-RPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGT 210
C SG G T D++EC L C + V C N + G
Sbjct: 669 L-CSSGL---GITTDGRDINECALDPEVCANGV-CENLRGSYRCVCNLGYEAGASG---- 719
Query: 211 GNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTT 270
+ C DVDECA C G C N+P GSY C G ++ T
Sbjct: 720 ------KDCTDVDECALNSLLCDNG-WCQNSP-----------GSYSCSCPPGFHFWQDT 761
Query: 271 RPCFDPDS-LVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
C D D L C CR N + KC + +GT C
Sbjct: 762 EICKDVDECLSSPCVSGVCR--NLAGSYTCKCGPGSRLDPSGTFC 804
Score = 35.5 bits (78), Expect = 0.75
Identities = 35/110 (31%), Positives = 50/110 (45%), Gaps = 14/110 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPG-SQTSDGQTCRTA--CS-ANPCFGGRVPCQDLPDGRYQC 73
LC +C++ G+RCE G T D + C+ C+ N C G C++LP G ++C
Sbjct: 1372 LCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFG--SCENLP-GMFRC 1428
Query: 74 GKCPSGFH--GNGVECYRISCRAN--TCFQGVSCEETQYGPKCGSCPTGY 119
C G+ G C I+ A+ C GV C T C SCP +
Sbjct: 1429 -ICNGGYELDRGGGNCTDINECADPVNCINGV-CINTPGSYLC-SCPQDF 1475
Score = 33.5 bits (73), Expect = 3.0
Identities = 29/93 (31%), Positives = 36/93 (38%), Gaps = 17/93 (18%)
Query: 216 REHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFD 275
R C+DVDEC + C G CVN P G+Y C G T + C D
Sbjct: 444 RGECIDVDECTS--SPCHHGD-CVNIP-----------GTYHCRCYPGFQATPTRQACVD 489
Query: 276 PDSLVKRCDPSYCRRFNAVCGFGQ-KCVCNTGW 307
D + C V G +CVCN G+
Sbjct: 490 VDECI--VSGGLCHLGRCVNTEGSFQCVCNAGF 520
Score = 31.9 bits (69), Expect = 9.2
Identities = 26/81 (32%), Positives = 31/81 (38%), Gaps = 8/81 (9%)
Query: 1 MHAGSMGDAGSMVTPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPC--- 56
+H G+ D LC G CV+ F C RCP G + SD A C
Sbjct: 240 IHTGACQDVDECQAVPGLCQGGSCVNMVGSFHC-RCPVGHRLSDSSAACEDYRAGACFSV 298
Query: 57 -FGGRVPCQDLPDGRYQCGKC 76
FGGR C G Y +C
Sbjct: 299 LFGGR--CAGDLAGHYTRRQC 317
>AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 70.9 bits (166), Expect = 2e-11
Identities = 92/318 (28%), Positives = 123/318 (38%), Gaps = 50/318 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQ-TSDGQTCR--TACSANPCFGGRVPCQDLPDGRYQCG 74
LC G C +TD ++C+ PG + T+ G C CS + C ++ G +QC
Sbjct: 1081 LCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNV-IGAFQC- 1138
Query: 75 KCPSGFHG--NGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQHV 129
C +GF + C I+ CR V C T+ +C SC GY + DGR C V
Sbjct: 1139 SCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRC-SCGQGYSLMPDGRACADV 1197
Query: 130 --CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSC 185
C+ + C + + C C G+ + TCVD+DECDL C
Sbjct: 1198 DECEENPRVCDQGHC--TNMPGGHRCL-CYDGFMATPDMRTCVDVDECDLNPHICLHGDC 1254
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N + +G G C DVDEC G NC C+N P
Sbjct: 1255 ENTK-GSFVCHCQLGYMVRKGATG---------CSDVDECEVGGHNCDSHASCLNIP--- 1301
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK---RCDP-SYCRRFNAVCGFGQKC 301
GS+ C G +V C D D V RC P C V G +C
Sbjct: 1302 --------GSFSCRCLPG--WVGDGFECHDLDECVSQEHRCSPRGDCLN---VPG-SYRC 1347
Query: 302 VCNTGWTGNGTVCGLDRD 319
C G+ G+G C DRD
Sbjct: 1348 TCRQGFAGDGFFCE-DRD 1364
Score = 62.9 bits (146), Expect = 4e-09
Identities = 92/315 (29%), Positives = 117/315 (37%), Gaps = 53/315 (16%)
Query: 21 GERCVDTDQGF---RCE--RCPGSQTSDGQTCRTACSANPCFGGRVPCQDLP-DGRYQCG 74
G RC DT Q F R E +C + + R CS P G PC+ P +G
Sbjct: 2006 GHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQ 2065
Query: 75 K-CPSGFHGN--GVECYRIS---CRAN--TCFQGVSCEETQYGPKCGSCPTGYVGD--GR 124
+ CP G HG G + R C N C GV C T +C CP GY D G
Sbjct: 2066 ELCPFG-HGAVPGPDDSREDVNECAENPGVCTNGV-CVNTDGSFRC-ECPFGYSLDFTGI 2122
Query: 125 QCQHV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN-GYTCVDMDECDLIRPCDD 181
C C PCG + C + +EC C G++ TC D+DEC L P
Sbjct: 2123 NCVDTDECSVGHPCG-QGTCT--NVIGGFEC-ACADGFEPGLMMTCEDIDECSL-NPLLC 2177
Query: 182 LVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC-PRGRLCVN 240
C N E G C DVDECADG+ +C RG C N
Sbjct: 2178 AFRCHNTEGSYLCTCPAGYTLREDG----------AMCRDVDECADGQQDCHARGMECKN 2227
Query: 241 TPQYPSNPVSSLQGSYICV-PCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ 299
L G++ CV P G + C D + P C V G
Sbjct: 2228 -----------LIGTFACVCPPGMRPLPGSGEGCTDDNEC--HAQPDLCVNGRCVNTAGS 2274
Query: 300 -KCVCNTGWTGNGTV 313
+C C+ G+ + T+
Sbjct: 2275 FRCDCDEGFQPSPTL 2289
Score = 61.3 bits (142), Expect = 1e-08
Identities = 64/231 (27%), Positives = 85/231 (36%), Gaps = 33/231 (14%)
Query: 24 CVDTDQGFRCERCPGSQT--SDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCGKCPS 78
C +T F C CP DG+TC+ + C + CQ L G + C +CP
Sbjct: 2420 CKNTKGSFLCS-CPRGYLLEEDGRTCK---DLDECTSRQHNCQFLCVNTVGAFTC-RCPP 2474
Query: 79 GFHGNGVECY---RISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQHVCDAQ 133
GF + C+ S + C C T +C C G+ V G C+ V +
Sbjct: 2475 GFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRC-ECHQGFTLVSSGHGCEDVNECD 2533
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGY--TCVDMDECDLIRPCDDLVSCRNEEXX 191
P + C + Y C CP G+ + CVD +EC L P SCRN
Sbjct: 2534 GPHRCQHGCQNQLGG--YRCS-CPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGG 2590
Query: 192 XXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G ++ C DVDECA R C C NTP
Sbjct: 2591 FRCVCPS----------GFDFDQALGGCQDVDECAGRRGPCSYS--CANTP 2629
Score = 57.6 bits (133), Expect = 2e-07
Identities = 79/293 (26%), Positives = 107/293 (36%), Gaps = 51/293 (17%)
Query: 17 KLCVGERCVDTDQGFRCERCPGSQ-TSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQC 73
++C C + G RC G T D +TC C NP C++ G + C
Sbjct: 1205 RVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTK-GSFVC 1263
Query: 74 GKCPSGF--HGNGVECYRIS-CRA--NTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQH 128
C G+ C + C + C SC C C G+VGDG +C
Sbjct: 1264 -HCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSC-RCLPGWVGDGFECH- 1320
Query: 129 VCDAQKPCGRERRCMPK----STSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDLV 183
D + +E RC P+ + Y C C G+ +G+ C D DEC + + CD+
Sbjct: 1321 --DLDECVSQEHRCSPRGDCLNVPGSYRCT-CRQGFAGDGFFCEDRDECAENVDLCDN-G 1376
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQ 243
C N G+ T + R C DVDECA G C G C N P
Sbjct: 1377 QCLN-------APGGYRCECEMGFDPTEDHRA---CQDVDECAQGNL-CAFGS-CENLP- 1423
Query: 244 YPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRC-DPSYCRRFNAVC 295
G + C+ GG+ C D + C DP C N VC
Sbjct: 1424 ----------GMFRCICNGGYELDRGGGNCTD----INECADPVNC--INGVC 1460
Score = 55.6 bits (128), Expect = 7e-07
Identities = 66/239 (27%), Positives = 94/239 (39%), Gaps = 36/239 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACS-ANPC-FGGR-----VPCQDLPDGR 70
+C+ C +T F C G G T CS + C GG C ++P G
Sbjct: 1248 ICLHGDCENTKGSFVCHCQLGYMVRKGAT---GCSDVDECEVGGHNCDSHASCLNIP-GS 1303
Query: 71 YQCGKCPSGFHGNGVECYRIS-C--RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ 127
+ C +C G+ G+G EC+ + C + + C C +C +C G+ GDG C+
Sbjct: 1304 FSC-RCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRC-TCRQGFAGDGFFCE 1361
Query: 128 H--VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLV 183
C +C+ + Y CE C G+ + C D+DEC C
Sbjct: 1362 DRDECAENVDLCDNGQCL--NAPGGYRCE-CEMGFDPTEDHRACQDVDECAQGNLCA-FG 1417
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
SC N RG GN C D++ECAD NC G +C+NTP
Sbjct: 1418 SCENLPGMFRCICNGGYELD----RGGGN------CTDINECAD-PVNCING-VCINTP 1464
Score = 55.2 bits (127), Expect = 9e-07
Identities = 88/361 (24%), Positives = 128/361 (35%), Gaps = 51/361 (14%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQ----TCRTACSANPCFGGRVPCQDLPDGRYQC 73
LC C +T F C C G D Q T C +P G+ C + P G ++C
Sbjct: 996 LCTHGTCRNTVGSFHCA-CAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTP-GSFEC 1053
Query: 74 GKCPSGFHGNGV---ECYRIS--CRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQC 126
+C G+ + C + R +G +C T KC CP G+ G C
Sbjct: 1054 -ECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKC-QCPPGHELTAKGTAC 1111
Query: 127 QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRP-CDDLV 183
+ + + G + ++C C +G+Q + CVD++EC + CD V
Sbjct: 1112 EDIDECSLSDGLCPHGQCVNVIGAFQCS-CHAGFQSTPDRQGCVDINECRVQNGGCD--V 1168
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRRE--------HCVDVDE-----CADGRA 230
C N E G + E HC ++ C DG
Sbjct: 1169 HCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFM 1228
Query: 231 NCPRGRLCVNTPQYPSNP-------VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLV--- 280
P R CV+ + NP + +GS++C G+ C D D
Sbjct: 1229 ATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGG 1288
Query: 281 KRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRCKKDNC 340
CD S+ N F C C GW G+G C DLD ++ C+ PR N
Sbjct: 1289 HNCD-SHASCLNIPGSF--SCRCLPGWVGDGFEC---HDLDECVSQEHRCS-PRGDCLNV 1341
Query: 341 P 341
P
Sbjct: 1342 P 1342
Score = 54.8 bits (126), Expect = 1e-06
Identities = 77/300 (25%), Positives = 107/300 (35%), Gaps = 51/300 (17%)
Query: 24 CVDTDQGFRCERCPG-SQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C++T+ +RC G S DG+ C C NP + C ++P G ++C C GF
Sbjct: 1170 CINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGG-HRC-LCYDGF 1227
Query: 81 HGNG-----VECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY-VGDGRQ-CQHVCDAQ 133
V+ + C G CE T+ C C GY V G C V + +
Sbjct: 1228 MATPDMRTCVDVDECDLNPHICLHG-DCENTKGSFVC-HCQLGYMVRKGATGCSDVDECE 1285
Query: 134 ---KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDLVSCRNEE 189
C C+ S + C C G+ +G+ C D+DEC C C N
Sbjct: 1286 VGGHNCDSHASCLNIPGS--FSCR-CLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVP 1342
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPV 249
QG+ G G C D DECA+ C G+ C+N P
Sbjct: 1343 GSYRCTCR-------QGFAGDGF-----FCEDRDECAENVDLCDNGQ-CLNAP------- 1382
Query: 250 SSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK--RCDPSYCRRFNAVCGFGQKCVCNTGW 307
G Y C G R C D D + C C + +C+CN G+
Sbjct: 1383 ----GGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMF----RCICNGGY 1434
Score = 54.8 bits (126), Expect = 1e-06
Identities = 90/342 (26%), Positives = 126/342 (36%), Gaps = 67/342 (19%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGG--RVPCQDLPDG-----R 70
LCV RCV+T FRC+ G Q S T PCF + C+ L R
Sbjct: 2262 LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTR 2321
Query: 71 YQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCP--TGYVGDGRQCQH 128
+C C G G G C + ++ + CP +GY +GR
Sbjct: 2322 AEC--CCGGGRGWGPRCELCPLPGTSAYRKL-------------CPHGSGYTAEGRDVDE 2366
Query: 129 VCDAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLI-RPCDDLVSC 185
C C+ S + C C +GY TC+DMDEC + +PC L C
Sbjct: 2367 -CRMLAHLCAHGECINSLGS--FRCH-CQAGYTPDATATTCLDMDECSQVPKPCTFL--C 2420
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
+N + RG E C D+DEC + NC LCVNT
Sbjct: 2421 KNTKGSFLCSCP----------RGYLLEEDGRTCKDLDECTSRQHNCQ--FLCVNT---- 2464
Query: 246 SNPVSSLQGSYIC-VPCGGHYYVNTTRPCFDPDSLVKRCDP--SYCRRFNAVCGFGQKCV 302
G++ C P G + + CFD D + P ++ N F +C
Sbjct: 2465 -------VGAFTCRCPPG---FTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSF--RCE 2512
Query: 303 CNTGWT--GNGTVCGLDRDLDGHPDEQLPC-NEPRCKKDNCP 341
C+ G+T +G C + DG Q C N+ + +CP
Sbjct: 2513 CHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCP 2554
Score = 48.4 bits (110), Expect = 1e-04
Identities = 56/229 (24%), Positives = 87/229 (37%), Gaps = 29/229 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTC--RTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
C++ +RC+ G + S G C R C P C D +G Y C C GF
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMD-TEGSYMC-LCHRGFQ 1837
Query: 82 GNGVE--CYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGR 138
+ + C I C C G +C+ C P V C + G+
Sbjct: 1838 ASADQTLCMDIDECDRQPCGNG-TCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1896
Query: 139 ERR---CMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSCRNEEXXXX 193
R C+ +T+ + C C G++ +G CVD +EC + +C+N E
Sbjct: 1897 VCRFGHCL--NTAGSFHCL-CQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFR 1953
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G + + +HC+D+DEC++ C G C N+P
Sbjct: 1954 CIC------------PPGFQVQSDHCIDIDECSEEPNLCLFG-TCTNSP 1989
Score = 47.6 bits (108), Expect = 2e-04
Identities = 53/186 (28%), Positives = 77/186 (41%), Gaps = 26/186 (13%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSD--GQTCRT-ACSANPCFGGRVPCQDLPDGRYQCG 74
LC+ RC+ T +RCE C T D G+ C+++PC G C ++P G Y C
Sbjct: 418 LCLNGRCLPTPSSYRCE-CNVGYTQDVRGECIDVDECTSSPCHHG--DCVNIP-GTYHC- 472
Query: 75 KCPSGFHGNGVE--CYRI-SC--RANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQC- 126
+C GF C + C C G C T+ +C C G+ DG+ C
Sbjct: 473 QCYPGFQATPTRQACVDVDECIVSGGLCHLG-RCVNTEGSFQC-VCNAGFELSPDGKNCV 530
Query: 127 -QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLV 183
+ C C C+ + S + C C G+ G+ C+D+DEC C +
Sbjct: 531 DHNECATSTMC-VNGVCLNEDGS--FSCL-CKPGFLLAPGGHYCMDIDECQTPGICVN-G 585
Query: 184 SCRNEE 189
C N E
Sbjct: 586 HCTNTE 591
Score = 47.2 bits (107), Expect = 2e-04
Identities = 85/324 (26%), Positives = 113/324 (34%), Gaps = 57/324 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKC- 76
LC+ C ++ F+C PG SD + + CF R Q R++ GKC
Sbjct: 1979 LCLFGTCTNSPGSFQCLCPPGFVLSD--------NGHRCFDTR---QSFCFTRFEAGKCS 2027
Query: 77 -PSGFHGNGVECYRISCRANTCFQGVSCEET-QYGPKCGS--CPTGYVG-----DGRQCQ 127
P F+ C S R + G CE Q G CP G+ D R+
Sbjct: 2028 VPKAFNTTKTRCC-CSKRPGEGW-GDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDV 2085
Query: 128 HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLVSC 185
+ C A+ P G + +T + CE CP GY + G CVD DEC + PC +C
Sbjct: 2086 NEC-AENP-GVCTNGVCVNTDGSFRCE-CPFGYSLDFTGINCVDTDECSVGHPCGQ-GTC 2141
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N G T C D+DEC+ C C NT
Sbjct: 2142 TN---VIGGFECACADGFEPGLMMT--------CEDIDECSLNPLLC--AFRCHNT---- 2184
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCN 304
+GSY+C G+ C D D + R G CVC
Sbjct: 2185 -------EGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCP 2237
Query: 305 TGW---TGNGTVCGLDRDLDGHPD 325
G G+G C D + PD
Sbjct: 2238 PGMRPLPGSGEGCTDDNECHAQPD 2261
Score = 44.4 bits (100), Expect = 0.002
Identities = 45/168 (26%), Positives = 67/168 (39%), Gaps = 21/168 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQT-CRTA--CSANPCFGGRVPCQDLPDGRYQCG 74
+C C+DT+ + C G Q S QT C C PC G C+++ G Y C
Sbjct: 1815 VCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGT--CKNII-GSYNC- 1870
Query: 75 KCPSGF----HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQH 128
C GF +G+ V+ + + C T C C G+ DG+ C
Sbjct: 1871 LCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHC-LCQDGFELTADGKNCVD 1929
Query: 129 VCDAQKPCGRERRCMP---KSTSPYYECEGCPSGYQWNGYTCVDMDEC 173
+ G C+P ++ + C CP G+Q C+D+DEC
Sbjct: 1930 TNECLSLAGT---CLPGTCQNLEGSFRCI-CPPGFQVQSDHCIDIDEC 1973
Score = 43.6 bits (98), Expect = 0.003
Identities = 66/259 (25%), Positives = 96/259 (37%), Gaps = 46/259 (17%)
Query: 69 GRYQCGKCPSGFHGNGV--ECYRIS-C--RANTCFQGVSCEETQYGPKCGSCPTGY-VGD 122
G ++C +CP+GF+ N + C + C R + C Q C +C C GY +
Sbjct: 1742 GSFRC-ECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC-KCTRGYKLSP 1799
Query: 123 GRQC--QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLIRP 178
G C ++ C CM T Y C C G+Q + C+D+DECD +P
Sbjct: 1800 GGACVGRNECREIPNVCSHGDCM--DTEGSYMCL-CHRGFQASADQTLCMDIDECDR-QP 1855
Query: 179 CDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLC 238
C + +C+N G+ T N CVD DEC R C
Sbjct: 1856 CGN-GTCKN-------IIGSYNCLCFPGFVVTHN----GDCVDFDECTTLVGQVCRFGHC 1903
Query: 239 VNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPD---SLVKRCDPSYCRRFNAVC 295
+NT GS+ C+ G + C D + SL C P C+
Sbjct: 1904 LNT-----------AGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEG-- 1950
Query: 296 GFGQKCVCNTGWTGNGTVC 314
+C+C G+ C
Sbjct: 1951 --SFRCICPPGFQVQSDHC 1967
Score = 42.7 bits (96), Expect = 0.005
Identities = 84/334 (25%), Positives = 122/334 (36%), Gaps = 59/334 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDG-QTCRTA--CSANPCFGGRVPCQDLPDGRYQCG 74
LC G CV+T F+CE PG S+ + C CS + G C + G Y C
Sbjct: 1573 LCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTL-GNYTC- 1630
Query: 75 KCPSGFH--GNGVECYRISCRANTCFQ---GVSCEETQYGPKCGSCPTGYVGDGRQCQHV 129
CP+ + G C + R + CF+ G E + C Y G+
Sbjct: 1631 VCPAEYLQVNGGNNC--MDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSY-NIGQAWNRP 1687
Query: 130 CDAQKPCGRERRCMPKSTSPYYE--CEGCPSGYQWNGYTC--VDMDECDLIRPCDDLVSC 185
C+A C P SP Y+ C G+ + +T +D+DEC I C
Sbjct: 1688 CEA---------C-PTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANGIC 1737
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N+ + G C DVDEC + C + C+N P
Sbjct: 1738 INQ----------IGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIP--- 1784
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCN 304
GSY C C Y ++ C + R P+ C + + G C+C+
Sbjct: 1785 --------GSYRC-KCTRGYKLSPGGACVGRNEC--REIPNVCSHGDCMDTEGSYMCLCH 1833
Query: 305 TGW--TGNGTVCGLDRDLDGHPDEQLPCNEPRCK 336
G+ + + T+C D+D D Q PC CK
Sbjct: 1834 RGFQASADQTLC---MDID-ECDRQ-PCGNGTCK 1862
Score = 39.5 bits (88), Expect = 0.046
Identities = 36/102 (35%), Positives = 43/102 (42%), Gaps = 17/102 (16%)
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGY-TCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXX 199
RC+P +S Y CE C GY + C+D+DEC PC C N
Sbjct: 423 RCLPTPSS--YRCE-CNVGYTQDVRGECIDVDECTS-SPCHH-GDCVN----------IP 467
Query: 200 XXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNT 241
Q + G R+ CVDVDEC C GR CVNT
Sbjct: 468 GTYHCQCYPGFQATPTRQACVDVDECIVSGGLCHLGR-CVNT 508
Score = 39.5 bits (88), Expect = 0.046
Identities = 54/216 (25%), Positives = 80/216 (37%), Gaps = 34/216 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPG-SQTSDGQTCRTACSANPCFGG--RVPC-QDLPD--GRY 71
+CV C +T+ FRC+ G + +DG+ C + C+G + C + P +
Sbjct: 581 ICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKS 640
Query: 72 QCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
+C C + HG G C + + FQ + C S G DGR
Sbjct: 641 EC-CCANPDHGFGEPCQLCPAKNSAEFQAL----------CSS-GLGITTDGRDINECAL 688
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLVSCRNEE 189
+ C + ++ Y C C GY+ +G C D+DEC L D C+N
Sbjct: 689 DPEVCANG---VCENLRGSYRCV-CNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSP 744
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDEC 225
W+ T E C DVDEC
Sbjct: 745 GSYSCSCPPGFHF----WQDT------EICKDVDEC 770
Score = 37.5 bits (83), Expect = 0.19
Identities = 86/345 (24%), Positives = 114/345 (33%), Gaps = 67/345 (19%)
Query: 8 DAGSMVTPFKLCVGERCVDTDQGFRCERCPGSQTS-DGQTC--------RTACSANPCFG 58
D + LC RCV+T+ F+C G + S DG+ C T C C
Sbjct: 489 DVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLN 548
Query: 59 --GRVPCQD------LPDGRY-----QC---GKCPSGFHGNGVECYRISCRANTCF--QG 100
G C P G Y +C G C +G N +R C G
Sbjct: 549 EDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDG 608
Query: 101 VSCEETQYGPKC------GSCPTGYVGDGRQCQHVC-DAQKPCGRERRCMPKSTSPYYEC 153
C +T C GSC + G + + C + G + P S ++
Sbjct: 609 RVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQA 668
Query: 154 EGCPSGYQWNGYTCV--DMDECDLI-RPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGT 210
C SG G T D++EC L C + V C N + G
Sbjct: 669 L-CSSGL---GITTDGRDINECALDPEVCANGV-CENLRGSYRCVCNLGYEAGASG---- 719
Query: 211 GNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTT 270
+ C DVDECA C G C N+P GSY C G ++ T
Sbjct: 720 ------KDCTDVDECALNSLLCDNG-WCQNSP-----------GSYSCSCPPGFHFWQDT 761
Query: 271 RPCFDPDS-LVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
C D D L C CR N + KC + +GT C
Sbjct: 762 EICKDVDECLSSPCVSGVCR--NLAGSYTCKCGPGSRLDPSGTFC 804
Score = 35.5 bits (78), Expect = 0.75
Identities = 35/110 (31%), Positives = 50/110 (45%), Gaps = 14/110 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPG-SQTSDGQTCRTA--CS-ANPCFGGRVPCQDLPDGRYQC 73
LC +C++ G+RCE G T D + C+ C+ N C G C++LP G ++C
Sbjct: 1372 LCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFG--SCENLP-GMFRC 1428
Query: 74 GKCPSGFH--GNGVECYRISCRAN--TCFQGVSCEETQYGPKCGSCPTGY 119
C G+ G C I+ A+ C GV C T C SCP +
Sbjct: 1429 -ICNGGYELDRGGGNCTDINECADPVNCINGV-CINTPGSYLC-SCPQDF 1475
Score = 31.9 bits (69), Expect = 9.2
Identities = 26/81 (32%), Positives = 31/81 (38%), Gaps = 8/81 (9%)
Query: 1 MHAGSMGDAGSMVTPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPC--- 56
+H G+ D LC G CV+ F C RCP G + SD A C
Sbjct: 240 IHTGACQDVDECQAVPGLCQGGSCVNMVGSFHC-RCPVGHRLSDSSAACEDYRAGACFSV 298
Query: 57 -FGGRVPCQDLPDGRYQCGKC 76
FGGR C G Y +C
Sbjct: 299 LFGGR--CAGDLAGHYTRRQC 317
>AL133553-4|CAI17860.1| 240|Homo sapiens protein ( Human DNA
sequence from clone GS1-174L6 on chromosome 1. ).
Length = 240
Score = 70.5 bits (165), Expect = 2e-11
Identities = 60/207 (28%), Positives = 87/207 (42%), Gaps = 37/207 (17%)
Query: 69 GRYQCGKCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYGPKC-GSCPTGYV-GDGRQ 125
G + CG C G+ G +C ++ CR N C C+ T+ G KC CP G +
Sbjct: 3 GSFHCG-CEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGT 61
Query: 126 CQHV--C-DAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLIRPCD 180
C + C D C + C ++T Y C CP GY Q G C+D+DEC+ C
Sbjct: 62 CIDIDECKDGTHQCRYNQIC--ENTRGSYRCV-CPRGYRSQGVGRPCMDIDECENTDACQ 118
Query: 181 DLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVN 240
C+N G++ T N + C D+DEC + +C R+C N
Sbjct: 119 H--ECKN-------TFGSYQCICPPGYQLTHNGKT---CQDIDECLEQNVHCGPNRMCFN 166
Query: 241 TPQYPSNPVSSLQGSYICV--PCGGHY 265
++GSY C+ PC +Y
Sbjct: 167 -----------MRGSYQCIDTPCPPNY 182
Score = 60.1 bits (139), Expect = 3e-08
Identities = 52/187 (27%), Positives = 76/187 (40%), Gaps = 32/187 (17%)
Query: 151 YECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGT 210
+ C GC GYQ G C+D++EC C C+N ++ GT
Sbjct: 5 FHC-GCEPGYQLKGRKCMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGM-TKAENGT 61
Query: 211 GNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTT 270
C+D+DEC DG C ++C NT +GSY CV G+
Sbjct: 62 --------CIDIDECKDGTHQCRYNQICENT-----------RGSYRCVCPRGYRSQGVG 102
Query: 271 RPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCNTGW--TGNGTVCGLDRDLDGHPDEQ 327
RPC D D C+ + + FG +C+C G+ T NG C +D+D ++
Sbjct: 103 RPCMDID----ECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTC---QDIDECLEQN 155
Query: 328 LPCNEPR 334
+ C R
Sbjct: 156 VHCGPNR 162
>AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein.
Length = 2816
Score = 70.5 bits (165), Expect = 2e-11
Identities = 91/318 (28%), Positives = 123/318 (38%), Gaps = 50/318 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQ-TSDGQTCR--TACSANPCFGGRVPCQDLPDGRYQCG 74
LC G C +TD ++C+ PG + T+ G C CS + C ++ G +QC
Sbjct: 1088 LCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNV-IGAFQC- 1145
Query: 75 KCPSGFHG--NGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQHV 129
C +GF + C I+ CR V C T+ +C SC GY + DGR C V
Sbjct: 1146 SCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRC-SCGQGYSLMPDGRACADV 1204
Query: 130 --CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSC 185
C+ + C + + C C G+ + TCVD+DECDL C
Sbjct: 1205 DECEENPRVCDQGHC--TNMPGGHRCL-CYDGFMATPDMRTCVDVDECDLNPHICLHGDC 1261
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N + +G G C DVDEC G NC C+N P
Sbjct: 1262 ENTK-GSFVCHCQLGYMVRKGATG---------CSDVDECEVGGHNCDSHASCLNIP--- 1308
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK---RCDP-SYCRRFNAVCGFGQKC 301
GS+ C G +V C D D + RC P C V G +C
Sbjct: 1309 --------GSFSCRCLPG--WVGDGFECHDLDECISQEHRCSPRGDCLN---VPG-SYRC 1354
Query: 302 VCNTGWTGNGTVCGLDRD 319
C G+ G+G C DRD
Sbjct: 1355 TCRQGFAGDGFFCE-DRD 1371
Score = 62.9 bits (146), Expect = 4e-09
Identities = 92/315 (29%), Positives = 117/315 (37%), Gaps = 53/315 (16%)
Query: 21 GERCVDTDQGF---RCE--RCPGSQTSDGQTCRTACSANPCFGGRVPCQDLP-DGRYQCG 74
G RC DT Q F R E +C + + R CS P G PC+ P +G
Sbjct: 2013 GHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQ 2072
Query: 75 K-CPSGFHGN--GVECYRIS---CRAN--TCFQGVSCEETQYGPKCGSCPTGYVGD--GR 124
+ CP G HG G + R C N C GV C T +C CP GY D G
Sbjct: 2073 ELCPFG-HGAVPGPDDSREDVNECAENPGVCTNGV-CVNTDGSFRC-ECPFGYSLDFTGI 2129
Query: 125 QCQHV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN-GYTCVDMDECDLIRPCDD 181
C C PCG + C + +EC C G++ TC D+DEC L P
Sbjct: 2130 NCVDTDECSVGHPCG-QGTCT--NVIGGFEC-ACADGFEPGLMMTCEDIDECSL-NPLLC 2184
Query: 182 LVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC-PRGRLCVN 240
C N E G C DVDECADG+ +C RG C N
Sbjct: 2185 AFRCHNTEGSYLCTCPAGYTLREDG----------AMCRDVDECADGQQDCHARGMECKN 2234
Query: 241 TPQYPSNPVSSLQGSYICV-PCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ 299
L G++ CV P G + C D + P C V G
Sbjct: 2235 -----------LIGTFACVCPPGMRPLPGSGEGCTDDNEC--HAQPDLCVNGRCVNTAGS 2281
Query: 300 -KCVCNTGWTGNGTV 313
+C C+ G+ + T+
Sbjct: 2282 FRCDCDEGFQPSPTL 2296
Score = 61.3 bits (142), Expect = 1e-08
Identities = 64/231 (27%), Positives = 85/231 (36%), Gaps = 33/231 (14%)
Query: 24 CVDTDQGFRCERCPGSQT--SDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCGKCPS 78
C +T F C CP DG+TC+ + C + CQ L G + C +CP
Sbjct: 2427 CKNTKGSFLCS-CPRGYLLEEDGRTCK---DLDECTSRQHNCQFLCVNTVGAFTC-RCPP 2481
Query: 79 GFHGNGVECY---RISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQHVCDAQ 133
GF + C+ S + C C T +C C G+ V G C+ V +
Sbjct: 2482 GFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRC-ECHQGFTLVSSGHGCEDVNECD 2540
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGY--TCVDMDECDLIRPCDDLVSCRNEEXX 191
P + C + Y C CP G+ + CVD +EC L P SCRN
Sbjct: 2541 GPHRCQHGCQNQLGG--YRCS-CPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGG 2597
Query: 192 XXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G ++ C DVDECA R C C NTP
Sbjct: 2598 FRCVCPS----------GFDFDQALGGCQDVDECAGRRGPCSYS--CANTP 2636
Score = 57.6 bits (133), Expect = 2e-07
Identities = 79/293 (26%), Positives = 107/293 (36%), Gaps = 51/293 (17%)
Query: 17 KLCVGERCVDTDQGFRCERCPGSQ-TSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQC 73
++C C + G RC G T D +TC C NP C++ G + C
Sbjct: 1212 RVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTK-GSFVC 1270
Query: 74 GKCPSGF--HGNGVECYRIS-CRA--NTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQH 128
C G+ C + C + C SC C C G+VGDG +C
Sbjct: 1271 -HCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSC-RCLPGWVGDGFECH- 1327
Query: 129 VCDAQKPCGRERRCMPK----STSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDLV 183
D + +E RC P+ + Y C C G+ +G+ C D DEC + + CD+
Sbjct: 1328 --DLDECISQEHRCSPRGDCLNVPGSYRCT-CRQGFAGDGFFCEDRDECAENVDLCDN-G 1383
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQ 243
C N G+ T + R C DVDECA G C G C N P
Sbjct: 1384 QCLN-------APGGYRCECEMGFDPTEDHRA---CQDVDECAQGNL-CAFGS-CENLP- 1430
Query: 244 YPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRC-DPSYCRRFNAVC 295
G + C+ GG+ C D + C DP C N VC
Sbjct: 1431 ----------GMFRCICNGGYELDRGGGNCTD----INECADPVNC--INGVC 1467
Score = 55.6 bits (128), Expect = 7e-07
Identities = 66/239 (27%), Positives = 94/239 (39%), Gaps = 36/239 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACS-ANPC-FGGR-----VPCQDLPDGR 70
+C+ C +T F C G G T CS + C GG C ++P G
Sbjct: 1255 ICLHGDCENTKGSFVCHCQLGYMVRKGAT---GCSDVDECEVGGHNCDSHASCLNIP-GS 1310
Query: 71 YQCGKCPSGFHGNGVECYRIS-C--RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ 127
+ C +C G+ G+G EC+ + C + + C C +C +C G+ GDG C+
Sbjct: 1311 FSC-RCLPGWVGDGFECHDLDECISQEHRCSPRGDCLNVPGSYRC-TCRQGFAGDGFFCE 1368
Query: 128 H--VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLV 183
C +C+ + Y CE C G+ + C D+DEC C
Sbjct: 1369 DRDECAENVDLCDNGQCL--NAPGGYRCE-CEMGFDPTEDHRACQDVDECAQGNLCA-FG 1424
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
SC N RG GN C D++ECAD NC G +C+NTP
Sbjct: 1425 SCENLPGMFRCICNGGYELD----RGGGN------CTDINECAD-PVNCING-VCINTP 1471
Score = 54.8 bits (126), Expect = 1e-06
Identities = 88/361 (24%), Positives = 128/361 (35%), Gaps = 51/361 (14%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQ----TCRTACSANPCFGGRVPCQDLPDGRYQC 73
LC C +T F C C G D Q T C +P G+ C + P G ++C
Sbjct: 1003 LCTHGTCRNTVGSFHCA-CAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTP-GSFEC 1060
Query: 74 GKCPSGFHGNGV---ECYRIS--CRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQC 126
+C G+ + C + R +G +C T KC CP G+ G C
Sbjct: 1061 -ECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKC-QCPPGHELTAKGTAC 1118
Query: 127 QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRP-CDDLV 183
+ + + G + ++C C +G+Q + CVD++EC + CD V
Sbjct: 1119 EDIDECSLSDGLCPHGQCVNVIGAFQCS-CHAGFQSTPDRQGCVDINECRVQNGGCD--V 1175
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRRE--------HCVDVDE-----CADGRA 230
C N E G + E HC ++ C DG
Sbjct: 1176 HCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFM 1235
Query: 231 NCPRGRLCVNTPQYPSNP-------VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLV--- 280
P R CV+ + NP + +GS++C G+ C D D
Sbjct: 1236 ATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGG 1295
Query: 281 KRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRCKKDNC 340
CD S+ N F C C GW G+G C DLD ++ C+ PR N
Sbjct: 1296 HNCD-SHASCLNIPGSF--SCRCLPGWVGDGFEC---HDLDECISQEHRCS-PRGDCLNV 1348
Query: 341 P 341
P
Sbjct: 1349 P 1349
Score = 54.8 bits (126), Expect = 1e-06
Identities = 77/300 (25%), Positives = 107/300 (35%), Gaps = 51/300 (17%)
Query: 24 CVDTDQGFRCERCPG-SQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C++T+ +RC G S DG+ C C NP + C ++P G ++C C GF
Sbjct: 1177 CINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGG-HRC-LCYDGF 1234
Query: 81 HGNG-----VECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY-VGDGRQ-CQHVCDAQ 133
V+ + C G CE T+ C C GY V G C V + +
Sbjct: 1235 MATPDMRTCVDVDECDLNPHICLHG-DCENTKGSFVC-HCQLGYMVRKGATGCSDVDECE 1292
Query: 134 ---KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDLVSCRNEE 189
C C+ S + C C G+ +G+ C D+DEC C C N
Sbjct: 1293 VGGHNCDSHASCLNIPGS--FSCR-CLPGWVGDGFECHDLDECISQEHRCSPRGDCLNVP 1349
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPV 249
QG+ G G C D DECA+ C G+ C+N P
Sbjct: 1350 GSYRCTCR-------QGFAGDGF-----FCEDRDECAENVDLCDNGQ-CLNAP------- 1389
Query: 250 SSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK--RCDPSYCRRFNAVCGFGQKCVCNTGW 307
G Y C G R C D D + C C + +C+CN G+
Sbjct: 1390 ----GGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMF----RCICNGGY 1441
Score = 54.8 bits (126), Expect = 1e-06
Identities = 90/342 (26%), Positives = 126/342 (36%), Gaps = 67/342 (19%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGG--RVPCQDLPDG-----R 70
LCV RCV+T FRC+ G Q S T PCF + C+ L R
Sbjct: 2269 LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTR 2328
Query: 71 YQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCP--TGYVGDGRQCQH 128
+C C G G G C + ++ + CP +GY +GR
Sbjct: 2329 AEC--CCGGGRGWGPRCELCPLPGTSAYRKL-------------CPHGSGYTAEGRDVDE 2373
Query: 129 VCDAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLI-RPCDDLVSC 185
C C+ S + C C +GY TC+DMDEC + +PC L C
Sbjct: 2374 -CRMLAHLCAHGECINSLGS--FRCH-CQAGYTPDATATTCLDMDECSQVPKPCTFL--C 2427
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
+N + RG E C D+DEC + NC LCVNT
Sbjct: 2428 KNTKGSFLCSCP----------RGYLLEEDGRTCKDLDECTSRQHNCQ--FLCVNT---- 2471
Query: 246 SNPVSSLQGSYIC-VPCGGHYYVNTTRPCFDPDSLVKRCDP--SYCRRFNAVCGFGQKCV 302
G++ C P G + + CFD D + P ++ N F +C
Sbjct: 2472 -------VGAFTCRCPPG---FTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSF--RCE 2519
Query: 303 CNTGWT--GNGTVCGLDRDLDGHPDEQLPC-NEPRCKKDNCP 341
C+ G+T +G C + DG Q C N+ + +CP
Sbjct: 2520 CHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCP 2561
Score = 48.0 bits (109), Expect = 1e-04
Identities = 53/186 (28%), Positives = 77/186 (41%), Gaps = 26/186 (13%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSD--GQTCRT-ACSANPCFGGRVPCQDLPDGRYQCG 74
LC+ RC+ T +RCE C T D G+ C+++PC G C ++P G Y C
Sbjct: 425 LCLNGRCLPTPSSYRCE-CNVGYTQDVRGECIDVDECTSSPCHHG--DCVNIP-GTYHC- 479
Query: 75 KCPSGFHGNGVE--CYRI-SC--RANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQC- 126
+C GF C + C C G C T+ +C C G+ DG+ C
Sbjct: 480 RCYPGFQATPTRQACVDVDECIVSGGLCHLG-RCVNTEGSFQC-VCNAGFELSPDGKNCV 537
Query: 127 -QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLV 183
+ C C C+ + S + C C G+ G+ C+D+DEC C +
Sbjct: 538 DHNECATSTMC-VNGVCLNEDGS--FSCL-CKPGFLLAPGGHYCMDIDECQTPGICVN-G 592
Query: 184 SCRNEE 189
C N E
Sbjct: 593 HCTNTE 598
Score = 47.2 bits (107), Expect = 2e-04
Identities = 85/324 (26%), Positives = 113/324 (34%), Gaps = 57/324 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKC- 76
LC+ C ++ F+C PG SD + + CF R Q R++ GKC
Sbjct: 1986 LCLFGTCTNSPGSFQCLCPPGFVLSD--------NGHRCFDTR---QSFCFTRFEAGKCS 2034
Query: 77 -PSGFHGNGVECYRISCRANTCFQGVSCEET-QYGPKCGS--CPTGYVG-----DGRQCQ 127
P F+ C S R + G CE Q G CP G+ D R+
Sbjct: 2035 VPKAFNTTKTRCC-CSKRPGEGW-GDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDV 2092
Query: 128 HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLVSC 185
+ C A+ P G + +T + CE CP GY + G CVD DEC + PC +C
Sbjct: 2093 NEC-AENP-GVCTNGVCVNTDGSFRCE-CPFGYSLDFTGINCVDTDECSVGHPCGQ-GTC 2148
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N G T C D+DEC+ C C NT
Sbjct: 2149 TN---VIGGFECACADGFEPGLMMT--------CEDIDECSLNPLLC--AFRCHNT---- 2191
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCN 304
+GSY+C G+ C D D + R G CVC
Sbjct: 2192 -------EGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCP 2244
Query: 305 TGW---TGNGTVCGLDRDLDGHPD 325
G G+G C D + PD
Sbjct: 2245 PGMRPLPGSGEGCTDDNECHAQPD 2268
Score = 46.8 bits (106), Expect = 3e-04
Identities = 55/229 (24%), Positives = 87/229 (37%), Gaps = 29/229 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTC--RTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
C++ +RC+ G + S G C + C P C D +G Y C C GF
Sbjct: 1787 CINIPGSYRCKCTRGYKLSPGGACVGQNECREIPNVCSHGDCMD-TEGSYMC-LCHRGFQ 1844
Query: 82 GNGVE--CYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGR 138
+ + C I C C G +C+ C P V C + G+
Sbjct: 1845 ASADQTLCMDIDECDRQPCGNG-TCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQ 1903
Query: 139 ERR---CMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSCRNEEXXXX 193
R C+ +T+ + C C G++ +G CVD +EC + +C+N E
Sbjct: 1904 VCRFGHCL--NTAGSFHCL-CQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFR 1960
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G + + +HC+D+DEC++ C G C N+P
Sbjct: 1961 CIC------------PPGFQVQSDHCIDIDECSEEPNLCLFG-TCTNSP 1996
Score = 45.2 bits (102), Expect = 0.001
Identities = 67/259 (25%), Positives = 96/259 (37%), Gaps = 46/259 (17%)
Query: 69 GRYQCGKCPSGFHGNGV--ECYRIS-C--RANTCFQGVSCEETQYGPKCGSCPTGY-VGD 122
G ++C +CP+GF+ N + C + C R + C Q C +C C GY +
Sbjct: 1749 GSFRC-ECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC-KCTRGYKLSP 1806
Query: 123 GRQC--QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLIRP 178
G C Q+ C CM T Y C C G+Q + C+D+DECD +P
Sbjct: 1807 GGACVGQNECREIPNVCSHGDCM--DTEGSYMCL-CHRGFQASADQTLCMDIDECDR-QP 1862
Query: 179 CDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLC 238
C + +C+N G+ T N CVD DEC R C
Sbjct: 1863 CGN-GTCKN-------IIGSYNCLCFPGFVVTHN----GDCVDFDECTTLVGQVCRFGHC 1910
Query: 239 VNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPD---SLVKRCDPSYCRRFNAVC 295
+NT GS+ C+ G + C D + SL C P C+
Sbjct: 1911 LNT-----------AGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEG-- 1957
Query: 296 GFGQKCVCNTGWTGNGTVC 314
+C+C G+ C
Sbjct: 1958 --SFRCICPPGFQVQSDHC 1974
Score = 44.4 bits (100), Expect = 0.002
Identities = 45/168 (26%), Positives = 67/168 (39%), Gaps = 21/168 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQT-CRTA--CSANPCFGGRVPCQDLPDGRYQCG 74
+C C+DT+ + C G Q S QT C C PC G C+++ G Y C
Sbjct: 1822 VCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGT--CKNII-GSYNC- 1877
Query: 75 KCPSGF----HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQH 128
C GF +G+ V+ + + C T C C G+ DG+ C
Sbjct: 1878 LCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHC-LCQDGFELTADGKNCVD 1936
Query: 129 VCDAQKPCGRERRCMP---KSTSPYYECEGCPSGYQWNGYTCVDMDEC 173
+ G C+P ++ + C CP G+Q C+D+DEC
Sbjct: 1937 TNECLSLAGT---CLPGTCQNLEGSFRCI-CPPGFQVQSDHCIDIDEC 1980
Score = 42.3 bits (95), Expect = 0.007
Identities = 84/334 (25%), Positives = 122/334 (36%), Gaps = 59/334 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDG-QTCRTA--CSANPCFGGRVPCQDLPDGRYQCG 74
LC G CV+T F+CE PG S+ + C CS + G C + G Y C
Sbjct: 1580 LCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPGTCYNTL-GNYTC- 1637
Query: 75 KCPSGFH--GNGVECYRISCRANTCFQ---GVSCEETQYGPKCGSCPTGYVGDGRQCQHV 129
CP+ + G C + R + CF+ G E + C Y G+
Sbjct: 1638 VCPAEYLQVNGGNNC--MDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSY-NIGQAWNRP 1694
Query: 130 CDAQKPCGRERRCMPKSTSPYYE--CEGCPSGYQWNGYTC--VDMDECDLIRPCDDLVSC 185
C+A C P SP Y+ C G+ + +T +D+DEC I C
Sbjct: 1695 CEA---------C-PTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANGIC 1744
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N+ + G C DVDEC + C + C+N P
Sbjct: 1745 INQ----------IGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIP--- 1791
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCN 304
GSY C C Y ++ C + R P+ C + + G C+C+
Sbjct: 1792 --------GSYRC-KCTRGYKLSPGGACVGQNEC--REIPNVCSHGDCMDTEGSYMCLCH 1840
Query: 305 TGW--TGNGTVCGLDRDLDGHPDEQLPCNEPRCK 336
G+ + + T+C D+D D Q PC CK
Sbjct: 1841 RGFQASADQTLC---MDID-ECDRQ-PCGNGTCK 1869
Score = 39.5 bits (88), Expect = 0.046
Identities = 54/216 (25%), Positives = 80/216 (37%), Gaps = 34/216 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPG-SQTSDGQTCRTACSANPCFGG--RVPC-QDLPD--GRY 71
+CV C +T+ FRC+ G + +DG+ C + C+G + C + P +
Sbjct: 588 ICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKS 647
Query: 72 QCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
+C C + HG G C + + FQ + C S G DGR
Sbjct: 648 EC-CCANPDHGFGEPCQLCPAKNSAEFQAL----------CSS-GLGITTDGRDINECAL 695
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLVSCRNEE 189
+ C + ++ Y C C GY+ +G C D+DEC L D C+N
Sbjct: 696 DPEVCANG---VCENLRGSYRCV-CNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSP 751
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDEC 225
W+ T E C DVDEC
Sbjct: 752 GSYSCSCPPGFHF----WQDT------EICKDVDEC 777
Score = 37.5 bits (83), Expect = 0.19
Identities = 86/345 (24%), Positives = 114/345 (33%), Gaps = 67/345 (19%)
Query: 8 DAGSMVTPFKLCVGERCVDTDQGFRCERCPGSQTS-DGQTC--------RTACSANPCFG 58
D + LC RCV+T+ F+C G + S DG+ C T C C
Sbjct: 496 DVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLN 555
Query: 59 --GRVPCQD------LPDGRY-----QC---GKCPSGFHGNGVECYRISCRANTCF--QG 100
G C P G Y +C G C +G N +R C G
Sbjct: 556 EDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDG 615
Query: 101 VSCEETQYGPKC------GSCPTGYVGDGRQCQHVC-DAQKPCGRERRCMPKSTSPYYEC 153
C +T C GSC + G + + C + G + P S ++
Sbjct: 616 RVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKNSAEFQA 675
Query: 154 EGCPSGYQWNGYTCV--DMDECDLI-RPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGT 210
C SG G T D++EC L C + V C N + G
Sbjct: 676 L-CSSGL---GITTDGRDINECALDPEVCANGV-CENLRGSYRCVCNLGYEAGASG---- 726
Query: 211 GNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTT 270
+ C DVDECA C G C N+P GSY C G ++ T
Sbjct: 727 ------KDCTDVDECALNSLLCDNG-WCQNSP-----------GSYSCSCPPGFHFWQDT 768
Query: 271 RPCFDPDS-LVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
C D D L C CR N + KC + +GT C
Sbjct: 769 EICKDVDECLSSPCVSGVCR--NLAGSYTCKCGPGSRLDPSGTFC 811
Score = 35.5 bits (78), Expect = 0.75
Identities = 35/110 (31%), Positives = 50/110 (45%), Gaps = 14/110 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPG-SQTSDGQTCRTA--CS-ANPCFGGRVPCQDLPDGRYQC 73
LC +C++ G+RCE G T D + C+ C+ N C G C++LP G ++C
Sbjct: 1379 LCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFG--SCENLP-GMFRC 1435
Query: 74 GKCPSGFH--GNGVECYRISCRAN--TCFQGVSCEETQYGPKCGSCPTGY 119
C G+ G C I+ A+ C GV C T C SCP +
Sbjct: 1436 -ICNGGYELDRGGGNCTDINECADPVNCINGV-CINTPGSYLC-SCPQDF 1482
Score = 33.5 bits (73), Expect = 3.0
Identities = 29/93 (31%), Positives = 36/93 (38%), Gaps = 17/93 (18%)
Query: 216 REHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFD 275
R C+DVDEC + C G CVN P G+Y C G T + C D
Sbjct: 451 RGECIDVDECTS--SPCHHGD-CVNIP-----------GTYHCRCYPGFQATPTRQACVD 496
Query: 276 PDSLVKRCDPSYCRRFNAVCGFGQ-KCVCNTGW 307
D + C V G +CVCN G+
Sbjct: 497 VDECI--VSGGLCHLGRCVNTEGSFQCVCNAGF 527
Score = 31.9 bits (69), Expect = 9.2
Identities = 26/81 (32%), Positives = 31/81 (38%), Gaps = 8/81 (9%)
Query: 1 MHAGSMGDAGSMVTPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPC--- 56
+H G+ D LC G CV+ F C RCP G + SD A C
Sbjct: 247 IHTGACQDVDECQAVPGLCQGGSCVNMVGSFHC-RCPVGHRLSDSSAACEDYRAGACFSV 305
Query: 57 -FGGRVPCQDLPDGRYQCGKC 76
FGGR C G Y +C
Sbjct: 306 LFGGR--CAGDLAGHYTRRQC 324
>AF525689-1|AAN77133.1| 988|Homo sapiens signal
peptide-CUB-EGF-like domain containing protein 1
protein.
Length = 988
Score = 70.1 bits (164), Expect = 3e-11
Identities = 78/273 (28%), Positives = 115/273 (42%), Gaps = 45/273 (16%)
Query: 24 CVDTDQG-FRCERCPGSQTSDGQT-CRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF- 80
C +T +G C+ PG + Q C C+ G + C+D G CG C +
Sbjct: 177 CRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNG-GCQHSCEDTDTGP-TCG-CHQKYA 233
Query: 81 -HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQCQHVCDAQ-KPC 136
H +G C +C N +C++T G +C SCP G+ DG+ C+ + +
Sbjct: 234 PHSDGRTCIE-TCAVNNGGCDRTCKDTATGVRC-SCPVGFTLQPDGKTCKDINECLVNNG 291
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSCRNEEXXXXX 194
G + C ++T +EC GC GY+ + TC D+DEC R CD + C N
Sbjct: 292 GCDHFC--RNTVGSFEC-GCRKGYKLLTDERTCQDIDECSFERTCDHI--CINSPGSFQC 346
Query: 195 XXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQG 254
+G+ G HC DVDEC+ +C +G CVNT +G
Sbjct: 347 LCH-------RGYILYGTT----HCGDVDECSMSNGSCDQG--CVNT-----------KG 382
Query: 255 SYICV-PCGGHYYVNTTRPCFDPDSLVKRCDPS 286
SY CV P G + N + C + + R S
Sbjct: 383 SYECVCPPGRRLHWN-RKDCVETGKCLSRAKTS 414
Score = 37.9 bits (84), Expect = 0.14
Identities = 28/101 (27%), Positives = 44/101 (43%), Gaps = 10/101 (9%)
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPC- 136
SG G+ V+ S + C C+ KC C GY G+G+QC + + +
Sbjct: 26 SGLPGS-VDVDECSEGTDDCHIDAICQNAPKSYKC-LCKPGYKGEGKQCGDIDECENDYY 83
Query: 137 --GRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDEC 173
G C+ + Y C C G+ +G+ C+D+DEC
Sbjct: 84 NGGCVHECI--NIPGNYRCT-CFDGFMLAHDGHNCLDVDEC 121
>Z99756-1|CAI18854.1| 988|Homo sapiens protein ( Human DNA sequence
from clone RP1-100N22 on chromosome 22q13.31-13.33. ).
Length = 988
Score = 69.7 bits (163), Expect = 4e-11
Identities = 78/273 (28%), Positives = 115/273 (42%), Gaps = 45/273 (16%)
Query: 24 CVDTDQG-FRCERCPGSQTSDGQT-CRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF- 80
C +T +G C+ PG + Q C C+ G + C+D G CG C +
Sbjct: 177 CRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNG-GCQHSCEDTDTGP-TCG-CHQKYA 233
Query: 81 -HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQCQHVCDAQ-KPC 136
H +G C +C N +C++T G +C SCP G+ DG+ C+ + +
Sbjct: 234 LHSDGRTCIE-TCAVNNGGCDRTCKDTATGVRC-SCPVGFTLQPDGKTCKDINECLVNNG 291
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSCRNEEXXXXX 194
G + C ++T +EC GC GY+ + TC D+DEC R CD + C N
Sbjct: 292 GCDHFC--RNTVGSFEC-GCRKGYKLLTDERTCQDIDECSFERTCDHI--CINSPGSFQC 346
Query: 195 XXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQG 254
+G+ G HC DVDEC+ +C +G CVNT +G
Sbjct: 347 LCH-------RGYILYGTT----HCGDVDECSMSNGSCDQG--CVNT-----------KG 382
Query: 255 SYICV-PCGGHYYVNTTRPCFDPDSLVKRCDPS 286
SY CV P G + N + C + + R S
Sbjct: 383 SYECVCPPGRRLHWN-GKDCVETGKCLSRAKTS 414
Score = 41.5 bits (93), Expect = 0.011
Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 10/101 (9%)
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPC- 136
SG G+ V+ S + C C+ T KC C GY G+G+QC+ + + +
Sbjct: 26 SGLPGS-VDVDECSEGTDDCHIDAICQNTPKSYKC-LCKPGYKGEGKQCEDIDECENDYY 83
Query: 137 --GRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDEC 173
G C+ + Y C C G+ +G+ C+D+DEC
Sbjct: 84 NGGCVHECI--NIPGNYRCT-CFDGFMLAHDGHNCLDVDEC 121
Score = 32.7 bits (71), Expect = 5.3
Identities = 12/24 (50%), Positives = 17/24 (70%)
Query: 220 VDVDECADGRANCPRGRLCVNTPQ 243
VDVDEC++G +C +C NTP+
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPK 55
>Z82214-3|CAI21674.1| 988|Homo sapiens protein ( Human DNA sequence
from clone RP3-526I14 on chromosome 22. ).
Length = 988
Score = 69.7 bits (163), Expect = 4e-11
Identities = 78/273 (28%), Positives = 115/273 (42%), Gaps = 45/273 (16%)
Query: 24 CVDTDQG-FRCERCPGSQTSDGQT-CRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF- 80
C +T +G C+ PG + Q C C+ G + C+D G CG C +
Sbjct: 177 CRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNG-GCQHSCEDTDTGP-TCG-CHQKYA 233
Query: 81 -HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQCQHVCDAQ-KPC 136
H +G C +C N +C++T G +C SCP G+ DG+ C+ + +
Sbjct: 234 LHSDGRTCIE-TCAVNNGGCDRTCKDTATGVRC-SCPVGFTLQPDGKTCKDINECLVNNG 291
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSCRNEEXXXXX 194
G + C ++T +EC GC GY+ + TC D+DEC R CD + C N
Sbjct: 292 GCDHFC--RNTVGSFEC-GCRKGYKLLTDERTCQDIDECSFERTCDHI--CINSPGSFQC 346
Query: 195 XXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQG 254
+G+ G HC DVDEC+ +C +G CVNT +G
Sbjct: 347 LCH-------RGYILYGTT----HCGDVDECSMSNGSCDQG--CVNT-----------KG 382
Query: 255 SYICV-PCGGHYYVNTTRPCFDPDSLVKRCDPS 286
SY CV P G + N + C + + R S
Sbjct: 383 SYECVCPPGRRLHWN-GKDCVETGKCLSRAKTS 414
Score = 41.5 bits (93), Expect = 0.011
Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 10/101 (9%)
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPC- 136
SG G+ V+ S + C C+ T KC C GY G+G+QC+ + + +
Sbjct: 26 SGLPGS-VDVDECSEGTDDCHIDAICQNTPKSYKC-LCKPGYKGEGKQCEDIDECENDYY 83
Query: 137 --GRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDEC 173
G C+ + Y C C G+ +G+ C+D+DEC
Sbjct: 84 NGGCVHECI--NIPGNYRCT-CFDGFMLAHDGHNCLDVDEC 121
Score = 32.7 bits (71), Expect = 5.3
Identities = 12/24 (50%), Positives = 17/24 (70%)
Query: 220 VDVDECADGRANCPRGRLCVNTPQ 243
VDVDEC++G +C +C NTP+
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPK 55
>X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein.
Length = 3002
Score = 69.3 bits (162), Expect = 5e-11
Identities = 81/275 (29%), Positives = 109/275 (39%), Gaps = 47/275 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRT---ACS--ANPCFGGRVPCQDLPDGRYQ 72
+C+ C +T F C G G+T T C A+ C G C + G ++
Sbjct: 1421 ICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNC-GKHAVCTNTA-GSFK 1478
Query: 73 CGKCPSGFHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV 129
C C G+ G+G++C + C T C Q C+ T +C C GY GDG C +
Sbjct: 1479 CS-CSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRC-LCKEGYTGDGFTCTDL 1536
Query: 130 CDAQKP---CGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLIRPCDDLVS 184
+ + CG + C+ + Y CE C G+ +G C D+DEC L C +
Sbjct: 1537 DECSENLNLCGNGQ-CL--NAPGGYRCE-CDMGFVPSADGKACEDIDECSLPNIC-VFGT 1591
Query: 185 CRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQY 244
C N G GN C DV+EC D C G CVNTP
Sbjct: 1592 CHNLPGLFRCECEIGYELDRSG----GN------CTDVNECLD-PTTCISGN-CVNTP-- 1637
Query: 245 PSNPVSSLQGSYICVPCGGHYYVNTTR-PCFDPDS 278
GSYIC C + +N TR C D S
Sbjct: 1638 ---------GSYIC-DCPPDFELNPTRVGCVDTRS 1662
Score = 67.3 bits (157), Expect = 2e-10
Identities = 53/169 (31%), Positives = 76/169 (44%), Gaps = 21/169 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTS-DGQTCRTA--CSANP--CFGGRVPCQDLPDGRYQ 72
+C G +C + +RC G S D +TC C NP C G C++ G +
Sbjct: 1379 ICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGT--CENTK-GSFI 1435
Query: 73 CGKCPSGFHGNGVE--CYRIS-CR--ANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ 127
C C G+ G + C I+ C A+ C + C T KC SC G++GDG +C
Sbjct: 1436 C-HCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKC-SCSPGWIGDGIKCT 1493
Query: 128 HVCDAQKP---CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC 173
+ + C + C K+T Y C C GY +G+TC D+DEC
Sbjct: 1494 DLDECSNGTHMCSQHADC--KNTMGSYRCL-CKEGYTGDGFTCTDLDEC 1539
Score = 66.9 bits (156), Expect = 3e-10
Identities = 57/167 (34%), Positives = 76/167 (45%), Gaps = 18/167 (10%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTC--RTACS-ANPCFGGRVPCQDLPDGRYQCG 74
+C +C++TD +RCE CP T G C CS NPC G C+++ G ++C
Sbjct: 2267 VCKHGQCINTDGSYRCE-CPFGYTLAGNECVDTDECSVGNPC--GNGTCKNVIGG-FEC- 2321
Query: 75 KCPSGFH-GNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQC--QH 128
C GF G + C I+ C N C T YG CP GYV D R C +
Sbjct: 2322 TCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNT-YGSYECKCPVGYVLREDRRMCKDED 2380
Query: 129 VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDEC 173
C+ K E++ K+ Y C C GYQ +G CVD +EC
Sbjct: 2381 ECEEGKHDCTEKQMECKNLIGTYMCI-CGPGYQRRPDGEGCVDENEC 2426
Score = 66.5 bits (155), Expect = 4e-10
Identities = 86/336 (25%), Positives = 132/336 (39%), Gaps = 56/336 (16%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDG-QTC----RTACSANPCFGGRVPCQDLPDGRYQ 72
LC G C +T+ +RCE PG Q S C SA+ C GR C +L G+YQ
Sbjct: 1254 LCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGR--CVNL-IGKYQ 1310
Query: 73 CGKCPSGFHGNGVECYRISCRANTCFQG---VSCEETQYGPKCGSCPTGY--VGDGRQCQ 127
C C G+H + + + G C ++ +C SC G+ + D R C
Sbjct: 1311 CA-CNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYEC-SCQPGFALMPDQRSCT 1368
Query: 128 HV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLIRPCDDLV 183
+ C+ +C + Y C C G+ + TCVD++ECDL
Sbjct: 1369 DIDECEDNPNICDGGQC--TNIPGEYRCL-CYDGFMASEDMKTCVDVNECDLNPNICLSG 1425
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQ 243
+C N + G+ G ++ + C D++EC G NC + +C NT
Sbjct: 1426 TCENTK-------GSFICHCDMGYSG---KKGKTGCTDINECEIGAHNCGKHAVCTNT-- 1473
Query: 244 YPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSL---VKRCDP-SYCRRFNAVCGFGQ 299
GS+ C G ++ C D D C + C+ N + +
Sbjct: 1474 ---------AGSFKCSCSPG--WIGDGIKCTDLDECSNGTHMCSQHADCK--NTMGSY-- 1518
Query: 300 KCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRC 335
+C+C G+TG+G C DLD + C +C
Sbjct: 1519 RCLCKEGYTGDGFTC---TDLDECSENLNLCGNGQC 1551
Score = 55.6 bits (128), Expect = 7e-07
Identities = 67/234 (28%), Positives = 89/234 (38%), Gaps = 31/234 (13%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQT-CR--TACSANPCFGGRVPCQDLPDGRYQCG 74
+C +C+DT F C G +T+D QT C C + C G C++ G + C
Sbjct: 1990 ICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGT--CRNTI-GSFNC- 2045
Query: 75 KCPSGF---HGNGV----ECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQ 125
+C GF H N EC S N C G C T +C C GY DGR
Sbjct: 2046 RCNHGFILSHNNDCIDVDEC--ASGNGNLCRNG-QCINTVGSFQC-QCNEGYEVAPDGRT 2101
Query: 126 CQHVCDAQKPCGRERRCMP---KSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDL 182
C D + R+C P ++ Y C CP GY C D+DEC L
Sbjct: 2102 C---VDINECLLEPRKCAPGTCQNLDGSYRCI-CPPGYSLQNEKCEDIDECVEEPEICAL 2157
Query: 183 VSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGR 236
+C N E S G R + R +C E G+ + P+ R
Sbjct: 2158 GTCSNTEGSFKCLCPEGFSLSSSGRR--CQDLRMSYCYAKFE--GGKCSSPKSR 2207
Score = 54.0 bits (124), Expect = 2e-06
Identities = 65/230 (28%), Positives = 95/230 (41%), Gaps = 33/230 (14%)
Query: 24 CVDTDQGFRCERCPGSQ-TSDGQ-TCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
C++T +RC+ PG + TS GQ R C P C D G + C C +GF
Sbjct: 1955 CINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTV-GSFYC-LCHTGFK 2012
Query: 82 GNGVE--CYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGYV-GDGRQCQHVCDAQKPCG 137
N + C I+ C + C G +C T C C G++ C V + G
Sbjct: 2013 TNDDQTMCLDINECERDACGNG-TCRNTIGSFNC-RCNHGFILSHNNDCIDVDECASGNG 2070
Query: 138 ---RERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDL-IRPCDDLVSCRNEEXX 191
R +C+ +T ++C+ C GY+ +G TCVD++EC L R C +C+N +
Sbjct: 2071 NLCRNGQCI--NTVGSFQCQ-CNEGYEVAPDGRTCVDINECLLEPRKCAP-GTCQNLDGS 2126
Query: 192 XXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNT 241
G + E C D+DEC + C G C NT
Sbjct: 2127 YRCIC------------PPGYSLQNEKCEDIDECVEEPEICALG-TCSNT 2163
Score = 51.2 bits (117), Expect = 1e-05
Identities = 82/314 (26%), Positives = 113/314 (35%), Gaps = 51/314 (16%)
Query: 18 LCVGERCVDTDQGFRCERCPG-SQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKC 76
LC RCV+ ++C PG T D C + GG +G Y+C C
Sbjct: 1296 LCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECS-C 1354
Query: 77 PSGFH--GNGVECYRIS-CRAN-TCFQGVSCEETQYGPKCGSCPTGYVG--DGRQCQHV- 129
GF + C I C N G C +C C G++ D + C V
Sbjct: 1355 QPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRC-LCYDGFMASEDMKTCVDVN 1413
Query: 130 -CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN-GYT-CVDMDECDL-IRPCDDLVSC 185
CD C ++T + C C GY G T C D++EC++ C C
Sbjct: 1414 ECDLNPNICLSGTC--ENTKGSFICH-CDMGYSGKKGKTGCTDINECEIGAHNCGKHAVC 1470
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N S GW G G + C D+DEC++G C + C NT
Sbjct: 1471 TN-------TAGSFKCSCSPGWIGDGIK-----CTDLDECSNGTHMCSQHADCKNT---- 1514
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSL---VKRCDPSYCRRFNAVCGFGQKCV 302
GSY C+ G Y C D D + C C NA G+ +C
Sbjct: 1515 -------MGSYRCLCKEG--YTGDGFTCTDLDECSENLNLCGNGQC--LNAPGGY--RCE 1561
Query: 303 CNTGW--TGNGTVC 314
C+ G+ + +G C
Sbjct: 1562 CDMGFVPSADGKAC 1575
Score = 51.2 bits (117), Expect = 1e-05
Identities = 69/282 (24%), Positives = 108/282 (38%), Gaps = 54/282 (19%)
Query: 69 GRYQCGKCPSGFHGNG--VECYRIS-CRAN-TCFQGVSCEETQYGPKCGSCP------TG 118
G ++C +CP GF N + C I C+ C + C T +C P TG
Sbjct: 1918 GSFRC-ECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTG 1976
Query: 119 YVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLI 176
D +CQ + + C + C+ S Y C +G++ N C+D++EC+
Sbjct: 1977 QCNDRNECQEIPNI---CSHGQ-CIDTVGSFYCLCH---TGFKTNDDQTMCLDINECE-- 2027
Query: 177 RPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGR 236
R +CRN + G+ + N C+DVDECA G N R
Sbjct: 2028 RDACGNGTCRN-------TIGSFNCRCNHGFILSHNN----DCIDVDECASGNGNLCRNG 2076
Query: 237 LCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLV---KRCDPSYCRRFNA 293
C+NT GS+ C G+ R C D + + ++C P C+ +
Sbjct: 2077 QCINT-----------VGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDG 2125
Query: 294 VCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRC 335
+C+C G++ C D+D +E C C
Sbjct: 2126 ----SYRCICPPGYSLQNEKC---EDIDECVEEPEICALGTC 2160
Score = 50.8 bits (116), Expect = 2e-05
Identities = 51/170 (30%), Positives = 71/170 (41%), Gaps = 23/170 (13%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGK 75
LC RC+ T +RCE G Q C C NPC GG C + G Y C +
Sbjct: 590 LCQNGRCIPTPGSYRCECNKGFQLDLRGECIDVDECEKNPCAGGE--CIN-NQGSYTC-Q 645
Query: 76 CPSGFHG--NGVECYRI-SCRAN--TCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQH 128
C +G+ EC I C N C G C T C C G+ DG+ C+
Sbjct: 646 CRAGYQSTLTRTECRDIDECLQNGRICNNG-RCINTDGSFHC-VCNAGFHVTRDGKNCED 703
Query: 129 V--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECD 174
+ C + C C+ + S ++C C G+Q +G C D++EC+
Sbjct: 704 MDECSIRNMC-LNGMCINEDGS--FKCI-CKPGFQLASDGRYCKDINECE 749
Score = 50.4 bits (115), Expect = 2e-05
Identities = 53/189 (28%), Positives = 72/189 (38%), Gaps = 27/189 (14%)
Query: 8 DAGSMVTPFKLCVGERCVDTDQGFRCERCPGSQTS-DGQTCRTACSANPCFGGRVPCQDL 66
D TP +C+ RCV+TD +RCE PG DG+ C + C+GG
Sbjct: 744 DINECETP-GICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGG------- 795
Query: 67 PDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCE------ETQYGPKCGSCPTGYV 120
Y+ G+C G V C + G C+ +Y C S P G
Sbjct: 796 ----YKRGQCIKPLFG-AVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGP-GMT 849
Query: 121 GDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN--GYTCVDMDECDLIRP 178
G C C ++ Y+C C SGY+ + G CVD++EC L
Sbjct: 850 SAGSDINE-CALDPDICPNGIC--ENLRGTYKCI-CNSGYEVDSTGKNCVDINECVLNSL 905
Query: 179 CDDLVSCRN 187
D CRN
Sbjct: 906 LCDNGQCRN 914
Score = 49.2 bits (112), Expect = 6e-05
Identities = 76/286 (26%), Positives = 104/286 (36%), Gaps = 53/286 (18%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQ-TSDGQTCR--TACSA-NPCFGGRVPCQDLPDGRYQC 73
+C+ C++ D F+C PG Q SDG+ C+ C C GR C + DG Y+C
Sbjct: 712 MCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGR--CVNT-DGSYRC 768
Query: 74 GKCPSGFHG-NGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVC-D 131
P G +G C R+ TC+ G K G C G + + C
Sbjct: 769 ECFPGLAVGLDGRVCVDTHMRS-TCYGGY---------KRGQCIKPLFGAVTKSECCCAS 818
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV--DMDECDLIRPCDDLVSCRNEE 189
+ G + P S Y+ C SG G T D++EC L C N
Sbjct: 819 TEYAFGEPCQPCPAQNSAEYQAL-CSSG---PGMTSAGSDINECALDPDICPNGICENLR 874
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPV 249
S G ++CVD++EC C G+ C NTP
Sbjct: 875 GTYKCICNSGYEVDSTG----------KNCVDINECVLNSLLCDNGQ-CRNTP------- 916
Query: 250 SSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC 295
GS++C G Y + C D D C+ S C N VC
Sbjct: 917 ----GSFVCTCPKGFIYKPDLKTCEDID----ECESSPC--INGVC 952
Score = 47.2 bits (107), Expect = 2e-04
Identities = 52/179 (29%), Positives = 70/179 (39%), Gaps = 36/179 (20%)
Query: 141 RCMPKSTSPYYECEGCPSGYQWN-GYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXX 199
RC+P S Y CE C G+Q + C+D+DEC+ PC C N +
Sbjct: 595 RCIPTPGS--YRCE-CNKGFQLDLRGECIDVDECEK-NPCAG-GECINNQGSYTCQCRA- 648
Query: 200 XXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICV 259
G++ T R C D+DEC C GR C+NT GS+ CV
Sbjct: 649 ------GYQST---LTRTECRDIDECLQNGRICNNGR-CINT-----------DGSFHCV 687
Query: 260 PCGGHYYVNTTRPCFDPD--SLVKRCDPSYCRRFNAVCGFGQKCVCNTGW--TGNGTVC 314
G + + C D D S+ C C N F KC+C G+ +G C
Sbjct: 688 CNAGFHVTRDGKNCEDMDECSIRNMCLNGMC--INEDGSF--KCICKPGFQLASDGRYC 742
Score = 46.0 bits (104), Expect = 5e-04
Identities = 80/305 (26%), Positives = 111/305 (36%), Gaps = 56/305 (18%)
Query: 22 ERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCF--GGR---VPCQDLP-DGRYQCGK 75
+ C+D +G+ + G + R + + C GGR C+ P G K
Sbjct: 2460 DECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKK 2519
Query: 76 -CPSG--FHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGD--GRQCQHV- 129
CP G F NG + + C G C + C C TGY D G C +
Sbjct: 2520 LCPHGRGFMTNGADIDECKVIHDVCRNG-ECVNDRGSYHC-ICKTGYTPDITGTSCVDLN 2577
Query: 130 -CD-AQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLIRP-CDDLVS 184
C+ A KPC + K+T Y+C CP GY Q +G +C D+DEC + C L
Sbjct: 2578 ECNQAPKPCN----FICKNTEGSYQCS-CPKGYILQEDGRSCKDLDECATKQHNCQFL-- 2630
Query: 185 CRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQY 244
C N G + C+D +EC C +C NTP
Sbjct: 2631 CVNTIGGFTCKCP------------PGFTQHHTSCIDNNECTSDINLCGSKGICQNTP-- 2676
Query: 245 PSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLV--KRCDPSYCRRFNAVCGFGQKCV 302
GS+ C G T C D D RC C+ N + G+ +C
Sbjct: 2677 ---------GSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHG-CQ--NIIGGY--RCS 2722
Query: 303 CNTGW 307
C G+
Sbjct: 2723 CPQGY 2727
Score = 44.0 bits (99), Expect = 0.002
Identities = 52/192 (27%), Positives = 79/192 (41%), Gaps = 33/192 (17%)
Query: 8 DAGSMVTPFKLCVGERCVDTDQGFRCERCPG--SQTSDGQTCRTACSANPCFGGRVPCQD 65
D V ++C C +T+ F+C CP S +S G+ C+ + C+
Sbjct: 2144 DIDECVEEPEICALGTCSNTEGSFKC-LCPEGFSLSSSGRRCQDL-RMSYCYA------- 2194
Query: 66 LPDGRYQCGKC--PSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGS---CPTG-- 118
+++ GKC P + + EC C G CE P CP G
Sbjct: 2195 ----KFEGGKCSSPKSRNHSKQEC---CCALKGEGWGDPCELCPTEPDEAFRQICPYGSG 2247
Query: 119 -YVGDGRQCQHVCDAQKP--CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDL 175
VG + + ++P C + +C+ +T Y CE CP GY G CVD DEC +
Sbjct: 2248 IIVGPDDSAVDMDECKEPDVC-KHGQCI--NTDGSYRCE-CPFGYTLAGNECVDTDECSV 2303
Query: 176 IRPCDDLVSCRN 187
PC + +C+N
Sbjct: 2304 GNPCGN-GTCKN 2314
Score = 43.2 bits (97), Expect = 0.004
Identities = 40/119 (33%), Positives = 51/119 (42%), Gaps = 14/119 (11%)
Query: 17 KLCVGERCVDTDQGFRCERCPGSQ-TSDGQTCR--TACS-ANPCFGGRVPCQDLPDGRYQ 72
++C RC++TD F C G T DG+ C CS N C G C + DG ++
Sbjct: 670 RICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGM--CIN-EDGSFK 726
Query: 73 CGKCPSGFH--GNGVECYRIS-CRA-NTCFQGVSCEETQYGPKCGSCPTGYVG-DGRQC 126
C C GF +G C I+ C C G C T +C P VG DGR C
Sbjct: 727 C-ICKPGFQLASDGRYCKDINECETPGICMNG-RCVNTDGSYRCECFPGLAVGLDGRVC 783
Score = 42.3 bits (95), Expect = 0.007
Identities = 57/222 (25%), Positives = 80/222 (36%), Gaps = 37/222 (16%)
Query: 95 NTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKPCGRERRCMPKSTSPYYE 152
+ C G C T +C CP GY G +C C PCG C K+ +E
Sbjct: 2266 DVCKHG-QCINTDGSYRC-ECPFGYTLAGNECVDTDECSVGNPCGNGT-C--KNVIGGFE 2320
Query: 153 CEGCPSGYQWNGY-TCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTG 211
C C G++ TC D++EC P C N G
Sbjct: 2321 CT-CEEGFEPGPMMTCEDINECAQ-NPLLCAFRCVNTYGSYECKCPV----------GYV 2368
Query: 212 NERRREHCVDVDECADGRANCPRGRL-CVNTPQYPSNPVSSLQGSYICVPCG-GHYYVNT 269
R C D DEC +G+ +C ++ C N L G+Y+C+ CG G+
Sbjct: 2369 LREDRRMCKDEDECEEGKHDCTEKQMECKN-----------LIGTYMCI-CGPGYQRRPD 2416
Query: 270 TRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCNTGWTGN 310
C D + + P C + G C CN G+T +
Sbjct: 2417 GEGCVDENEC--QTKPGICENGRCLNTRGSYTCECNDGFTAS 2456
Score = 41.5 bits (93), Expect = 0.011
Identities = 86/335 (25%), Positives = 123/335 (36%), Gaps = 60/335 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPC----FGGRVPCQDLPDGRYQC 73
LC G +C++T F+C RCP + T R N C G C + G Y C
Sbjct: 1747 LCQGGKCINTFGSFQC-RCPTGYYLNEDT-RVCDDVNECETPGICGPGTCYNTV-GNYTC 1803
Query: 74 GKCPSGFHGNG----VECYRISCRANTCFQGVSCE-ETQYGPKCGSCPTGYVGDGRQCQH 128
P NG ++ R C N +C+ E + C Y GR
Sbjct: 1804 ICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSY-NIGRAWN- 1861
Query: 129 VCDAQKPCGRERRCMPKSTSPYYE-CEGCPSGYQWNGYTC--VDMDEC-DLIRPCDDLVS 184
KPC +C ST + C G+ + YT VD+DEC ++ C++ V
Sbjct: 1862 -----KPC---EQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGV- 1912
Query: 185 CRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQY 244
C N + G + C D+DEC +G C R C+NT
Sbjct: 1913 CIN----------MVGSFRCECPVGFFYNDKLLVCEDIDECQNGPV-CQRNAECINT--- 1958
Query: 245 PSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVC 303
GSY C C Y +T C D + + P+ C + G C+C
Sbjct: 1959 --------AGSYRC-DCKPGYRFTSTGQCNDRNECQE--IPNICSHGQCIDTVGSFYCLC 2007
Query: 304 NTGWTGNG--TVCGLDRDLDGHPDEQLPCNEPRCK 336
+TG+ N T+C LD + E+ C C+
Sbjct: 2008 HTGFKTNDDQTMC-----LDINECERDACGNGTCR 2037
Score = 36.3 bits (80), Expect = 0.43
Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 15/93 (16%)
Query: 18 LCVGERCVDTDQGFRCERCP-GSQTSD-GQTCR--TACSANP--CFGGRVPCQDLPDGRY 71
LC G C++T F C +CP G + ++ Q C CS P C GG C + Y
Sbjct: 387 LCQGGNCINTVGSFEC-KCPAGHKLNEVSQKCEDIDECSTIPGICEGGE--CTNTVSS-Y 442
Query: 72 QCGKCPSGFH--GNGVECYRISCRANTCFQGVS 102
C KCP GF+ +G C I R C+ ++
Sbjct: 443 FC-KCPPGFYTSPDGTRC--IDVRPGYCYTALT 472
Score = 35.9 bits (79), Expect = 0.57
Identities = 70/302 (23%), Positives = 110/302 (36%), Gaps = 47/302 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSD--GQTCRTACSANPCFGGRVPCQD--LP-DGRYQ 72
+C CV+T F+C+ CP T D G+ C CF R ++ LP GR++
Sbjct: 1051 VCKNGLCVNTRGSFKCQ-CPSGMTLDATGRICLDI-RLETCFL-RYEDEECTLPIAGRHR 1107
Query: 73 CGKC--PSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVC 130
C G EC R ++ + + K + + D +C+ +
Sbjct: 1108 MDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIP 1167
Query: 131 DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGY--TCVDMDECDLIRPCDDLVSCRNE 188
C +C ++T ++C C SG+ + C D+DEC + C N
Sbjct: 1168 SL---C-THGKC--RNTIGSFKCR-CDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 1220
Query: 189 EXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNP 248
+G+ ++C+D+DEC C RG +C NT
Sbjct: 1221 PGDFECKC-------DEGYES--GFMMMKNCMDIDECQRDPLLC-RGGVCHNT------- 1263
Query: 249 VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPS--YCRRFNAVCGFGQ-KCVCNT 305
+GSY C GH C D + C+ S C V G+ +C CN
Sbjct: 1264 ----EGSYRCECPPGHQLSPNISACID----INECELSAHLCPNGRCVNLIGKYQCACNP 1315
Query: 306 GW 307
G+
Sbjct: 1316 GY 1317
>U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 69.3 bits (162), Expect = 5e-11
Identities = 56/171 (32%), Positives = 69/171 (40%), Gaps = 15/171 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G CVD + GFRC PGS C+ PC G C D P G ++C C G+
Sbjct: 669 GGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHG--ICYDAPGG-FRC-VCEPGW 724
Query: 81 HGN--GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD-AQKPCG 137
G R +C + C G +C G C +CP G GRQC+ + PC
Sbjct: 725 SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHC-TCPPGV--QGRQCELLSPCTPNPCE 781
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
RC +S CP G W G C D+DEC PC C N
Sbjct: 782 HGGRC--ESAPGQLPVCSCPQG--WQGPRCQQDVDECAGPAPCGPHGICTN 828
Score = 63.7 bits (148), Expect = 2e-09
Identities = 56/167 (33%), Positives = 72/167 (43%), Gaps = 21/167 (12%)
Query: 19 CV-GERCVDTDQGFRCERCPGSQTSDGQTCR---TACSANPCFGGRVPCQDLPDGRYQCG 74
CV G C D GF C CP G TC+ C++ PC G C D PDG Y+C
Sbjct: 478 CVNGGVCKDRVNGFSC-TCPSG--FSGSTCQLDVDECASTPCRNG-AKCVDQPDG-YEC- 531
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQ 133
+C GF G + C + C G C + C +C GY G + Q C +Q
Sbjct: 532 RCAEGFEGTLCDRNVDDCSPDPCHHG-RCVDGIASFSC-ACAPGYTGTRCESQVDECRSQ 589
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPC 179
PC +C+ Y C CPSG G C V++D+C PC
Sbjct: 590 -PCRHGGKCL--DLVDKYLCR-CPSG--TTGVNCEVNIDDC-ASNPC 629
Score = 62.9 bits (146), Expect = 4e-09
Identities = 47/153 (30%), Positives = 60/153 (39%), Gaps = 16/153 (10%)
Query: 26 DTDQGFRCERCPGSQTSDGQTCRTACSANPC-FGGRVPCQDLPDG--RYQCGKCPSGFHG 82
D GFRC G QT + C + PC GG+ P G + C C F G
Sbjct: 1225 DPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTC-HCAQPFWG 1283
Query: 83 NGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTG--------YVGDGRQCQHVCDAQK 134
E SCR C GV C++T GP+C +CP G + G + A
Sbjct: 1284 PRCERVARSCRELQCPVGVPCQQTPRGPRC-ACPPGLSGPSCRSFPGSPPGASNASCAAA 1342
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC 167
PC C P +P++ C C G W G C
Sbjct: 1343 PCLHGGSCRPAPLAPFFRC-ACAQG--WTGPRC 1372
Score = 60.5 bits (140), Expect = 2e-08
Identities = 46/154 (29%), Positives = 70/154 (45%), Gaps = 14/154 (9%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHG 82
RCV+T F C+ G +T C + PC + C D G++ C C +GF G
Sbjct: 407 RCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPC-RNQATCLD-RIGQFTC-ICMAGFTG 463
Query: 83 NGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRER 140
E C+++ C G C++ G C +CP+G+ G CQ D A PC
Sbjct: 464 TYCEVDIDECQSSPCVNGGVCKDRVNGFSC-TCPSGF--SGSTCQLDVDECASTPCRNGA 520
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
+C+ + YEC C G++ G C ++D+C
Sbjct: 521 KCVDQPDG--YECR-CAEGFE--GTLCDRNVDDC 549
Score = 58.0 bits (134), Expect = 1e-07
Identities = 81/307 (26%), Positives = 107/307 (34%), Gaps = 52/307 (16%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQD---LPDGRYQCGKCP 77
G RC CP + C + PC GR CQ R+ C +CP
Sbjct: 52 GGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPC-AGRGVCQSSVVAGTARFSC-RCP 109
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ---HVCDAQK 134
GF G C ++ C G C G SCP GY GR C+ C +
Sbjct: 110 RGFRGPDCSLPD-PCLSSPCAHGARCSVGPDGRFLCSCPPGY--QGRSCRSDVDECRVGE 166
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXX 194
PC C+ +T + C+ CP+GY G C E + PC CRN
Sbjct: 167 PCRHGGTCL--NTPGSFRCQ-CPAGY--TGPLC----ENPAV-PCAP-SPCRNGGTCRQS 215
Query: 195 XXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQG 254
G+ G E V+VD+C R C G CV+
Sbjct: 216 GDLTYDCACLPGFEGQNCE------VNVDDCPGHR--CLNGGTCVDG-----------VN 256
Query: 255 SYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRR----FNAVCGFGQKCVCNTGWTGN 310
+Y C C + T + C + D + P+ C FN + G CVC GWTG
Sbjct: 257 TYNC-QCPPEW---TGQFCTE-DVDECQLQPNACHNGGTCFNTL--GGHSCVCVNGWTGE 309
Query: 311 GTVCGLD 317
+D
Sbjct: 310 SCSQNID 316
Score = 57.6 bits (133), Expect = 2e-07
Identities = 84/313 (26%), Positives = 118/313 (37%), Gaps = 39/313 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C+D F C G + + C ++PC G V C+D +G + C CPSGF G+
Sbjct: 446 CLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGV-CKDRVNG-FSC-TCPSGFSGS 502
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
+ C + C G C + G +C C G+ +G C D + PC R
Sbjct: 503 TCQLDVDECASTPCRNGAKCVDQPDGYEC-RCAEGF--EGTLCDRNVDDCSPDPC-HHGR 558
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C+ S + C C GY G C +DEC +PC C +
Sbjct: 559 CVDGIAS--FSC-ACAPGY--TGTRCESQVDEC-RSQPCRHGGKCLD-------LVDKYL 605
Query: 201 XXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRL-CVNTPQYPSNPVSSLQ-GSYIC 258
G G E + C + C G R CV P + + P+ +++
Sbjct: 606 CRCPSGTTGVNCEVNIDDCAS-NPCTFGVCRDGINRYDCVCQPGF-TGPLCNVEINECAS 663
Query: 259 VPCG-GHYYV---NTTRPCFDPDSLVKRC-DPSY-CRR---FNAVC---GFGQKCVCNTG 306
PCG G V N R P SL C PS+ C + +C G +CVC G
Sbjct: 664 SPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPG 723
Query: 307 WTGNGTVCGLDRD 319
W+G L RD
Sbjct: 724 WSGPRCSQSLARD 736
Score = 56.0 bits (129), Expect = 5e-07
Identities = 81/298 (27%), Positives = 111/298 (37%), Gaps = 49/298 (16%)
Query: 28 DQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGV-- 85
D + C PG + + + C + C G C D + Y C +CP + G
Sbjct: 217 DLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGT-CVDGVN-TYNC-QCPPEWTGQFCTE 273
Query: 86 ECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD-AQKPCGRERRCMP 144
+ + N C G +C T G C C G+ G+ Q++ D A C C
Sbjct: 274 DVDECQLQPNACHNGGTCFNTLGGHSC-VCVNGWTGESCS-QNIDDCATAVCFHGATCHD 331
Query: 145 KSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXS 204
+ S Y C CP G G C +D+ + PC + C
Sbjct: 332 RVASFY--C-ACPMGK--TGLLC-HLDDACVSNPCHEDAICDTNPVNGRAICTC-----P 380
Query: 205 QGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGH 264
G+ G ++ DVDEC+ G C CVNT QGS++C CG
Sbjct: 381 PGFTGGACDQ------DVDECSIGANPCEHLGRCVNT-----------QGSFLC-QCGRG 422
Query: 265 YYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC--GFGQ-KCVCNTGWTGNGTVCGLDRD 319
Y T P + D V C CR A C GQ C+C G+T GT C +D D
Sbjct: 423 Y----TGPRCETD--VNECLSGPCRN-QATCLDRIGQFTCICMAGFT--GTYCEVDID 471
Score = 56.0 bits (129), Expect = 5e-07
Identities = 49/175 (28%), Positives = 64/175 (36%), Gaps = 16/175 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRT---ACSANP--CFGGRVPCQDLPDGRYQCGK 75
G CVD + C+ CP T GQ C C P C G L G + C
Sbjct: 248 GGTCVDGVNTYNCQ-CPPEWT--GQFCTEDVDECQLQPNACHNGGTCFNTL--GGHSC-V 301
Query: 76 CPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
C +G+ G C CF G +C + C +CP G G C P
Sbjct: 302 CVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYC-ACPMGKTGLLCHLDDAC-VSNP 359
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDL-IRPCDDLVSCRNEE 189
C + C + C CP G+ G D+DEC + PC+ L C N +
Sbjct: 360 CHEDAICDTNPVNGRAICT-CPPGFT-GGACDQDVDECSIGANPCEHLGRCVNTQ 412
Score = 55.2 bits (127), Expect = 9e-07
Identities = 45/142 (31%), Positives = 58/142 (40%), Gaps = 10/142 (7%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPC-FGGRVPCQDLPDGRYQCGKCP 77
C RCVD F C PG + ++ C + PC GG+ C DL D +Y C +CP
Sbjct: 554 CHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGK--CLDLVD-KYLC-RCP 609
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCG 137
SG G E C +N C GV C + C C G+ G + A PCG
Sbjct: 610 SGTTGVNCEVNIDDCASNPCTFGV-CRDGINRYDC-VCQPGFTGPLCNVEINECASSPCG 667
Query: 138 RERRCMPKSTSPYYECEGCPSG 159
C+ + C CP G
Sbjct: 668 EGGSCVDGENG--FRCL-CPPG 686
Score = 47.6 bits (108), Expect = 2e-04
Identities = 45/149 (30%), Positives = 56/149 (37%), Gaps = 14/149 (9%)
Query: 44 GQTCRTACSANPCF-GGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCF-QGV 101
G +PC GGR C LP C CP G+ G + C + C +GV
Sbjct: 37 GAAAPPCLDGSPCANGGR--CTQLPSREAAC-LCPPGWVGERCQL-EDPCHSGPCAGRGV 92
Query: 102 SCEETQYGPKCGSC--PTGYVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSG 159
G SC P G+ G C PC RC + C CP G
Sbjct: 93 CQSSVVAGTARFSCRCPRGFRGPDCSLPDPC-LSSPCAHGARCSVGPDGRFL-CS-CPPG 149
Query: 160 YQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
YQ G +C D+DEC + PC +C N
Sbjct: 150 YQ--GRSCRSDVDECRVGEPCRHGGTCLN 176
Score = 47.2 bits (107), Expect = 2e-04
Identities = 45/167 (26%), Positives = 60/167 (35%), Gaps = 14/167 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D F C PG C +NPC G C D + C CP G+
Sbjct: 861 GGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGT--CTDHV-ASFTC-TCPPGY 916
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C ++CF G +C + C C GY G CQH D +PC
Sbjct: 917 GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSC-LCRPGYT--GAHCQHEADPCLSRPCLH 973
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSC 185
C + P + C S + G C + + +PC + C
Sbjct: 974 GGVC--SAAHPGFRCTCLES---FTGPQCQTLVDWCSRQPCQNGGRC 1015
Score = 43.6 bits (98), Expect = 0.003
Identities = 77/305 (25%), Positives = 104/305 (34%), Gaps = 47/305 (15%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C G+ CE PG + + C++ PC G C DL RY C CP G
Sbjct: 1096 GGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGG-SCIDLV-ARYLC-SCPPGT 1152
Query: 81 HGNGVECYRISC-------RANTCFQGVSCEETQYGPKCGSCPTGYVG-----DGRQCQH 128
G E C C +C + G +C +CP GY G D +C+
Sbjct: 1153 LGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRC-TCPPGYTGLRCEADINECRS 1211
Query: 129 -VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCR 186
C A R C+ + + C C +G+ +G C + C+ +PC CR
Sbjct: 1212 GACHA----AHTRDCL-QDPGGGFRCL-CHAGF--SGPRCQTVLSPCE-SQPCQHGGQCR 1262
Query: 187 NEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADG--RANCPRGRLCVNTPQY 244
+Q + G ER C ++ +C G PRG C P
Sbjct: 1263 --PSPGPGGGLTFTCHCAQPFWGPRCERVARSCREL-QCPVGVPCQQTPRGPRCACPPGL 1319
Query: 245 PSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCN 304
S GS P G PC S C P+ F +C C
Sbjct: 1320 SGPSCRSFPGS----PPGASNASCAAAPCLHGGS----CRPAPLAPF-------FRCACA 1364
Query: 305 TGWTG 309
GWTG
Sbjct: 1365 QGWTG 1369
Score = 42.3 bits (95), Expect = 0.007
Identities = 49/176 (27%), Positives = 69/176 (39%), Gaps = 21/176 (11%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G CVD F C PG + Q C + PC G V C G ++C C F
Sbjct: 936 GGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGV-CSAAHPG-FRC-TCLESF 992
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG---DGRQ--CQHVC----- 130
G + C C G C +T G C CP G+ G D R C+
Sbjct: 993 TGPQCQTLVDWCSRQPCQNGGRCVQT--GAYC-LCPPGWSGRLCDIRSLPCREAAAQIGV 1049
Query: 131 DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCR 186
++ C +C+ + +S Y C CP G + + ++D C L +PC +CR
Sbjct: 1050 RLEQLCQAGGQCVDEDSSHY--CV-CPEG-RTGSHCEQEVDPC-LAQPCQHGGTCR 1100
Score = 41.9 bits (94), Expect = 0.009
Identities = 45/159 (28%), Positives = 60/159 (37%), Gaps = 24/159 (15%)
Query: 28 DQGFRCERCPGS-------QTSDGQTCRT---ACSANPCFGGRVPCQDLPDGRYQCGKCP 77
+ G RCE PG Q G C+ C+ G C +L G + C C
Sbjct: 781 EHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLA-GSFSC-TCH 838
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKP 135
G+ G + C N C G SC++ C SC G+ G +C D P
Sbjct: 839 GGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSC-SCLPGFAGP--RCARDVDECLSNP 895
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
CG C S + C CP GY G+ C D+ +C
Sbjct: 896 CG-PGTCTDHVAS--FTCT-CPPGY--GGFHCEQDLPDC 928
Score = 41.5 bits (93), Expect = 0.011
Identities = 49/183 (26%), Positives = 64/183 (34%), Gaps = 20/183 (10%)
Query: 63 CQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGD 122
C D D + C CP G G+ E C A C G +C G C C GY GD
Sbjct: 1061 CVD-EDSSHYC-VCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMC-ECLPGYNGD 1117
Query: 123 GRQCQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPC 179
C+ D A +PC C+ Y C CP G G C ++ D+C P
Sbjct: 1118 --NCEDDVDECASQPCQHGGSCI--DLVARYLC-SCPPGTL--GVLCEINEDDCGPGPPL 1170
Query: 180 DDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCV 239
D C + G+ G E D++EC G + R C+
Sbjct: 1171 DSGPRCLH-NGTCVDLVGGFRCTCPPGYTGLRCE------ADINECRSGACHAAHTRDCL 1223
Query: 240 NTP 242
P
Sbjct: 1224 QDP 1226
>L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein.
Length = 2871
Score = 69.3 bits (162), Expect = 5e-11
Identities = 81/275 (29%), Positives = 109/275 (39%), Gaps = 47/275 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRT---ACS--ANPCFGGRVPCQDLPDGRYQ 72
+C+ C +T F C G G+T T C A+ C G C + G ++
Sbjct: 1290 ICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNC-GKHAVCTNTA-GSFK 1347
Query: 73 CGKCPSGFHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV 129
C C G+ G+G++C + C T C Q C+ T +C C GY GDG C +
Sbjct: 1348 CS-CSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRC-LCKEGYTGDGFTCTDL 1405
Query: 130 CDAQKP---CGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLIRPCDDLVS 184
+ + CG + C+ + Y CE C G+ +G C D+DEC L C +
Sbjct: 1406 DECSENLNLCGNGQ-CL--NAPGGYRCE-CDMGFVPSADGKACEDIDECSLPNIC-VFGT 1460
Query: 185 CRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQY 244
C N G GN C DV+EC D C G CVNTP
Sbjct: 1461 CHNLPGLFRCECEIGYELDRSG----GN------CTDVNECLD-PTTCISGN-CVNTP-- 1506
Query: 245 PSNPVSSLQGSYICVPCGGHYYVNTTR-PCFDPDS 278
GSYIC C + +N TR C D S
Sbjct: 1507 ---------GSYIC-DCPPDFELNPTRVGCVDTRS 1531
Score = 67.3 bits (157), Expect = 2e-10
Identities = 53/169 (31%), Positives = 76/169 (44%), Gaps = 21/169 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTS-DGQTCRTA--CSANP--CFGGRVPCQDLPDGRYQ 72
+C G +C + +RC G S D +TC C NP C G C++ G +
Sbjct: 1248 ICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGT--CENTK-GSFI 1304
Query: 73 CGKCPSGFHGNGVE--CYRIS-CR--ANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ 127
C C G+ G + C I+ C A+ C + C T KC SC G++GDG +C
Sbjct: 1305 C-HCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKC-SCSPGWIGDGIKCT 1362
Query: 128 HVCDAQKP---CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC 173
+ + C + C K+T Y C C GY +G+TC D+DEC
Sbjct: 1363 DLDECSNGTHMCSQHADC--KNTMGSYRCL-CKEGYTGDGFTCTDLDEC 1408
Score = 66.9 bits (156), Expect = 3e-10
Identities = 57/167 (34%), Positives = 76/167 (45%), Gaps = 18/167 (10%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTC--RTACS-ANPCFGGRVPCQDLPDGRYQCG 74
+C +C++TD +RCE CP T G C CS NPC G C+++ G ++C
Sbjct: 2136 VCKHGQCINTDGSYRCE-CPFGYTLAGNECVDTDECSVGNPC--GNGTCKNVIGG-FEC- 2190
Query: 75 KCPSGFH-GNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQC--QH 128
C GF G + C I+ C N C T YG CP GYV D R C +
Sbjct: 2191 TCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNT-YGSYECKCPVGYVLREDRRMCKDED 2249
Query: 129 VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDEC 173
C+ K E++ K+ Y C C GYQ +G CVD +EC
Sbjct: 2250 ECEEGKHDCTEKQMECKNLIGTYMCI-CGPGYQRRPDGEGCVDENEC 2295
Score = 66.5 bits (155), Expect = 4e-10
Identities = 86/336 (25%), Positives = 132/336 (39%), Gaps = 56/336 (16%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDG-QTC----RTACSANPCFGGRVPCQDLPDGRYQ 72
LC G C +T+ +RCE PG Q S C SA+ C GR C +L G+YQ
Sbjct: 1123 LCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGR--CVNL-IGKYQ 1179
Query: 73 CGKCPSGFHGNGVECYRISCRANTCFQG---VSCEETQYGPKCGSCPTGY--VGDGRQCQ 127
C C G+H + + + G C ++ +C SC G+ + D R C
Sbjct: 1180 CA-CNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYEC-SCQPGFALMPDQRSCT 1237
Query: 128 HV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLIRPCDDLV 183
+ C+ +C + Y C C G+ + TCVD++ECDL
Sbjct: 1238 DIDECEDNPNICDGGQC--TNIPGEYRCL-CYDGFMASEDMKTCVDVNECDLNPNICLSG 1294
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQ 243
+C N + G+ G ++ + C D++EC G NC + +C NT
Sbjct: 1295 TCENTK-------GSFICHCDMGYSG---KKGKTGCTDINECEIGAHNCGKHAVCTNT-- 1342
Query: 244 YPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSL---VKRCDP-SYCRRFNAVCGFGQ 299
GS+ C G ++ C D D C + C+ N + +
Sbjct: 1343 ---------AGSFKCSCSPG--WIGDGIKCTDLDECSNGTHMCSQHADCK--NTMGSY-- 1387
Query: 300 KCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRC 335
+C+C G+TG+G C DLD + C +C
Sbjct: 1388 RCLCKEGYTGDGFTC---TDLDECSENLNLCGNGQC 1420
Score = 55.6 bits (128), Expect = 7e-07
Identities = 67/234 (28%), Positives = 89/234 (38%), Gaps = 31/234 (13%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQT-CR--TACSANPCFGGRVPCQDLPDGRYQCG 74
+C +C+DT F C G +T+D QT C C + C G C++ G + C
Sbjct: 1859 ICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGT--CRNTI-GSFNC- 1914
Query: 75 KCPSGF---HGNGV----ECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQ 125
+C GF H N EC S N C G C T +C C GY DGR
Sbjct: 1915 RCNHGFILSHNNDCIDVDEC--ASGNGNLCRNG-QCINTVGSFQC-QCNEGYEVAPDGRT 1970
Query: 126 CQHVCDAQKPCGRERRCMP---KSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDL 182
C D + R+C P ++ Y C CP GY C D+DEC L
Sbjct: 1971 C---VDINECLLEPRKCAPGTCQNLDGSYRCI-CPPGYSLQNEKCEDIDECVEEPEICAL 2026
Query: 183 VSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGR 236
+C N E S G R + R +C E G+ + P+ R
Sbjct: 2027 GTCSNTEGSFKCLCPEGFSLSSSGRR--CQDLRMSYCYAKFE--GGKCSSPKSR 2076
Score = 54.0 bits (124), Expect = 2e-06
Identities = 65/230 (28%), Positives = 95/230 (41%), Gaps = 33/230 (14%)
Query: 24 CVDTDQGFRCERCPGSQ-TSDGQ-TCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
C++T +RC+ PG + TS GQ R C P C D G + C C +GF
Sbjct: 1824 CINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTV-GSFYC-LCHTGFK 1881
Query: 82 GNGVE--CYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGYV-GDGRQCQHVCDAQKPCG 137
N + C I+ C + C G +C T C C G++ C V + G
Sbjct: 1882 TNDDQTMCLDINECERDACGNG-TCRNTIGSFNC-RCNHGFILSHNNDCIDVDECASGNG 1939
Query: 138 ---RERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDL-IRPCDDLVSCRNEEXX 191
R +C+ +T ++C+ C GY+ +G TCVD++EC L R C +C+N +
Sbjct: 1940 NLCRNGQCI--NTVGSFQCQ-CNEGYEVAPDGRTCVDINECLLEPRKCAP-GTCQNLDGS 1995
Query: 192 XXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNT 241
G + E C D+DEC + C G C NT
Sbjct: 1996 YRCIC------------PPGYSLQNEKCEDIDECVEEPEICALG-TCSNT 2032
Score = 51.2 bits (117), Expect = 1e-05
Identities = 82/314 (26%), Positives = 113/314 (35%), Gaps = 51/314 (16%)
Query: 18 LCVGERCVDTDQGFRCERCPG-SQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKC 76
LC RCV+ ++C PG T D C + GG +G Y+C C
Sbjct: 1165 LCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECS-C 1223
Query: 77 PSGFH--GNGVECYRIS-CRAN-TCFQGVSCEETQYGPKCGSCPTGYVG--DGRQCQHV- 129
GF + C I C N G C +C C G++ D + C V
Sbjct: 1224 QPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRC-LCYDGFMASEDMKTCVDVN 1282
Query: 130 -CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN-GYT-CVDMDECDL-IRPCDDLVSC 185
CD C ++T + C C GY G T C D++EC++ C C
Sbjct: 1283 ECDLNPNICLSGTC--ENTKGSFICH-CDMGYSGKKGKTGCTDINECEIGAHNCGKHAVC 1339
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N S GW G G + C D+DEC++G C + C NT
Sbjct: 1340 TN-------TAGSFKCSCSPGWIGDGIK-----CTDLDECSNGTHMCSQHADCKNT---- 1383
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSL---VKRCDPSYCRRFNAVCGFGQKCV 302
GSY C+ G Y C D D + C C NA G+ +C
Sbjct: 1384 -------MGSYRCLCKEG--YTGDGFTCTDLDECSENLNLCGNGQC--LNAPGGY--RCE 1430
Query: 303 CNTGW--TGNGTVC 314
C+ G+ + +G C
Sbjct: 1431 CDMGFVPSADGKAC 1444
Score = 51.2 bits (117), Expect = 1e-05
Identities = 69/282 (24%), Positives = 108/282 (38%), Gaps = 54/282 (19%)
Query: 69 GRYQCGKCPSGFHGNG--VECYRIS-CRAN-TCFQGVSCEETQYGPKCGSCP------TG 118
G ++C +CP GF N + C I C+ C + C T +C P TG
Sbjct: 1787 GSFRC-ECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTG 1845
Query: 119 YVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLI 176
D +CQ + + C + C+ S Y C +G++ N C+D++EC+
Sbjct: 1846 QCNDRNECQEIPNI---CSHGQ-CIDTVGSFYCLCH---TGFKTNDDQTMCLDINECE-- 1896
Query: 177 RPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGR 236
R +CRN + G+ + N C+DVDECA G N R
Sbjct: 1897 RDACGNGTCRN-------TIGSFNCRCNHGFILSHNN----DCIDVDECASGNGNLCRNG 1945
Query: 237 LCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLV---KRCDPSYCRRFNA 293
C+NT GS+ C G+ R C D + + ++C P C+ +
Sbjct: 1946 QCINT-----------VGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDG 1994
Query: 294 VCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRC 335
+C+C G++ C D+D +E C C
Sbjct: 1995 ----SYRCICPPGYSLQNEKC---EDIDECVEEPEICALGTC 2029
Score = 50.8 bits (116), Expect = 2e-05
Identities = 51/170 (30%), Positives = 71/170 (41%), Gaps = 23/170 (13%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGK 75
LC RC+ T +RCE G Q C C NPC GG C + G Y C +
Sbjct: 459 LCQNGRCIPTPGSYRCECNKGFQLDLRGECIDVDECEKNPCAGGE--CIN-NQGSYTC-Q 514
Query: 76 CPSGFHG--NGVECYRI-SCRAN--TCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQH 128
C +G+ EC I C N C G C T C C G+ DG+ C+
Sbjct: 515 CRAGYQSTLTRTECRDIDECLQNGRICNNG-RCINTDGSFHC-VCNAGFHVTRDGKNCED 572
Query: 129 V--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECD 174
+ C + C C+ + S ++C C G+Q +G C D++EC+
Sbjct: 573 MDECSIRNMC-LNGMCINEDGS--FKCI-CKPGFQLASDGRYCKDINECE 618
Score = 50.4 bits (115), Expect = 2e-05
Identities = 53/189 (28%), Positives = 72/189 (38%), Gaps = 27/189 (14%)
Query: 8 DAGSMVTPFKLCVGERCVDTDQGFRCERCPGSQTS-DGQTCRTACSANPCFGGRVPCQDL 66
D TP +C+ RCV+TD +RCE PG DG+ C + C+GG
Sbjct: 613 DINECETP-GICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGG------- 664
Query: 67 PDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCE------ETQYGPKCGSCPTGYV 120
Y+ G+C G V C + G C+ +Y C S P G
Sbjct: 665 ----YKRGQCIKPLFG-AVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGP-GMT 718
Query: 121 GDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN--GYTCVDMDECDLIRP 178
G C C ++ Y+C C SGY+ + G CVD++EC L
Sbjct: 719 SAGSDINE-CALDPDICPNGIC--ENLRGTYKCI-CNSGYEVDSTGKNCVDINECVLNSL 774
Query: 179 CDDLVSCRN 187
D CRN
Sbjct: 775 LCDNGQCRN 783
Score = 49.2 bits (112), Expect = 6e-05
Identities = 76/286 (26%), Positives = 104/286 (36%), Gaps = 53/286 (18%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQ-TSDGQTCR--TACSA-NPCFGGRVPCQDLPDGRYQC 73
+C+ C++ D F+C PG Q SDG+ C+ C C GR C + DG Y+C
Sbjct: 581 MCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGR--CVNT-DGSYRC 637
Query: 74 GKCPSGFHG-NGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVC-D 131
P G +G C R+ TC+ G K G C G + + C
Sbjct: 638 ECFPGLAVGLDGRVCVDTHMRS-TCYGGY---------KRGQCIKPLFGAVTKSECCCAS 687
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV--DMDECDLIRPCDDLVSCRNEE 189
+ G + P S Y+ C SG G T D++EC L C N
Sbjct: 688 TEYAFGEPCQPCPAQNSAEYQAL-CSSG---PGMTSAGSDINECALDPDICPNGICENLR 743
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPV 249
S G ++CVD++EC C G+ C NTP
Sbjct: 744 GTYKCICNSGYEVDSTG----------KNCVDINECVLNSLLCDNGQ-CRNTP------- 785
Query: 250 SSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC 295
GS++C G Y + C D D C+ S C N VC
Sbjct: 786 ----GSFVCTCPKGFIYKPDLKTCEDID----ECESSPC--INGVC 821
Score = 47.2 bits (107), Expect = 2e-04
Identities = 52/179 (29%), Positives = 70/179 (39%), Gaps = 36/179 (20%)
Query: 141 RCMPKSTSPYYECEGCPSGYQWN-GYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXX 199
RC+P S Y CE C G+Q + C+D+DEC+ PC C N +
Sbjct: 464 RCIPTPGS--YRCE-CNKGFQLDLRGECIDVDECEK-NPCAG-GECINNQGSYTCQCRA- 517
Query: 200 XXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICV 259
G++ T R C D+DEC C GR C+NT GS+ CV
Sbjct: 518 ------GYQST---LTRTECRDIDECLQNGRICNNGR-CINT-----------DGSFHCV 556
Query: 260 PCGGHYYVNTTRPCFDPD--SLVKRCDPSYCRRFNAVCGFGQKCVCNTGW--TGNGTVC 314
G + + C D D S+ C C N F KC+C G+ +G C
Sbjct: 557 CNAGFHVTRDGKNCEDMDECSIRNMCLNGMC--INEDGSF--KCICKPGFQLASDGRYC 611
Score = 46.0 bits (104), Expect = 5e-04
Identities = 80/305 (26%), Positives = 111/305 (36%), Gaps = 56/305 (18%)
Query: 22 ERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCF--GGR---VPCQDLP-DGRYQCGK 75
+ C+D +G+ + G + R + + C GGR C+ P G K
Sbjct: 2329 DECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKK 2388
Query: 76 -CPSG--FHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGD--GRQCQHV- 129
CP G F NG + + C G C + C C TGY D G C +
Sbjct: 2389 LCPHGRGFMTNGADIDECKVIHDVCRNG-ECVNDRGSYHC-ICKTGYTPDITGTSCVDLN 2446
Query: 130 -CD-AQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLIRP-CDDLVS 184
C+ A KPC + K+T Y+C CP GY Q +G +C D+DEC + C L
Sbjct: 2447 ECNQAPKPCN----FICKNTEGSYQCS-CPKGYILQEDGRSCKDLDECATKQHNCQFL-- 2499
Query: 185 CRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQY 244
C N G + C+D +EC C +C NTP
Sbjct: 2500 CVNTIGGFTCKCP------------PGFTQHHTSCIDNNECTSDINLCGSKGICQNTP-- 2545
Query: 245 PSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLV--KRCDPSYCRRFNAVCGFGQKCV 302
GS+ C G T C D D RC C+ N + G+ +C
Sbjct: 2546 ---------GSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHG-CQ--NIIGGY--RCS 2591
Query: 303 CNTGW 307
C G+
Sbjct: 2592 CPQGY 2596
Score = 44.0 bits (99), Expect = 0.002
Identities = 52/192 (27%), Positives = 79/192 (41%), Gaps = 33/192 (17%)
Query: 8 DAGSMVTPFKLCVGERCVDTDQGFRCERCPG--SQTSDGQTCRTACSANPCFGGRVPCQD 65
D V ++C C +T+ F+C CP S +S G+ C+ + C+
Sbjct: 2013 DIDECVEEPEICALGTCSNTEGSFKC-LCPEGFSLSSSGRRCQDL-RMSYCYA------- 2063
Query: 66 LPDGRYQCGKC--PSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGS---CPTG-- 118
+++ GKC P + + EC C G CE P CP G
Sbjct: 2064 ----KFEGGKCSSPKSRNHSKQEC---CCALKGEGWGDPCELCPTEPDEAFRQICPYGSG 2116
Query: 119 -YVGDGRQCQHVCDAQKP--CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDL 175
VG + + ++P C + +C+ +T Y CE CP GY G CVD DEC +
Sbjct: 2117 IIVGPDDSAVDMDECKEPDVC-KHGQCI--NTDGSYRCE-CPFGYTLAGNECVDTDECSV 2172
Query: 176 IRPCDDLVSCRN 187
PC + +C+N
Sbjct: 2173 GNPCGN-GTCKN 2183
Score = 43.2 bits (97), Expect = 0.004
Identities = 40/119 (33%), Positives = 51/119 (42%), Gaps = 14/119 (11%)
Query: 17 KLCVGERCVDTDQGFRCERCPGSQ-TSDGQTCR--TACS-ANPCFGGRVPCQDLPDGRYQ 72
++C RC++TD F C G T DG+ C CS N C G C + DG ++
Sbjct: 539 RICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGM--CIN-EDGSFK 595
Query: 73 CGKCPSGFH--GNGVECYRIS-CRA-NTCFQGVSCEETQYGPKCGSCPTGYVG-DGRQC 126
C C GF +G C I+ C C G C T +C P VG DGR C
Sbjct: 596 C-ICKPGFQLASDGRYCKDINECETPGICMNG-RCVNTDGSYRCECFPGLAVGLDGRVC 652
Score = 42.3 bits (95), Expect = 0.007
Identities = 57/222 (25%), Positives = 80/222 (36%), Gaps = 37/222 (16%)
Query: 95 NTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKPCGRERRCMPKSTSPYYE 152
+ C G C T +C CP GY G +C C PCG C K+ +E
Sbjct: 2135 DVCKHG-QCINTDGSYRC-ECPFGYTLAGNECVDTDECSVGNPCGNGT-C--KNVIGGFE 2189
Query: 153 CEGCPSGYQWNGY-TCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTG 211
C C G++ TC D++EC P C N G
Sbjct: 2190 CT-CEEGFEPGPMMTCEDINECAQ-NPLLCAFRCVNTYGSYECKCPV----------GYV 2237
Query: 212 NERRREHCVDVDECADGRANCPRGRL-CVNTPQYPSNPVSSLQGSYICVPCG-GHYYVNT 269
R C D DEC +G+ +C ++ C N L G+Y+C+ CG G+
Sbjct: 2238 LREDRRMCKDEDECEEGKHDCTEKQMECKN-----------LIGTYMCI-CGPGYQRRPD 2285
Query: 270 TRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCNTGWTGN 310
C D + + P C + G C CN G+T +
Sbjct: 2286 GEGCVDENEC--QTKPGICENGRCLNTRGSYTCECNDGFTAS 2325
Score = 41.5 bits (93), Expect = 0.011
Identities = 86/335 (25%), Positives = 123/335 (36%), Gaps = 60/335 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPC----FGGRVPCQDLPDGRYQC 73
LC G +C++T F+C RCP + T R N C G C + G Y C
Sbjct: 1616 LCQGGKCINTFGSFQC-RCPTGYYLNEDT-RVCDDVNECETPGICGPGTCYNTV-GNYTC 1672
Query: 74 GKCPSGFHGNG----VECYRISCRANTCFQGVSCE-ETQYGPKCGSCPTGYVGDGRQCQH 128
P NG ++ R C N +C+ E + C Y GR
Sbjct: 1673 ICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSY-NIGRAWN- 1730
Query: 129 VCDAQKPCGRERRCMPKSTSPYYE-CEGCPSGYQWNGYTC--VDMDEC-DLIRPCDDLVS 184
KPC +C ST + C G+ + YT VD+DEC ++ C++ V
Sbjct: 1731 -----KPC---EQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGV- 1781
Query: 185 CRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQY 244
C N + G + C D+DEC +G C R C+NT
Sbjct: 1782 CIN----------MVGSFRCECPVGFFYNDKLLVCEDIDECQNGPV-CQRNAECINT--- 1827
Query: 245 PSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVC 303
GSY C C Y +T C D + + P+ C + G C+C
Sbjct: 1828 --------AGSYRC-DCKPGYRFTSTGQCNDRNECQE--IPNICSHGQCIDTVGSFYCLC 1876
Query: 304 NTGWTGNG--TVCGLDRDLDGHPDEQLPCNEPRCK 336
+TG+ N T+C LD + E+ C C+
Sbjct: 1877 HTGFKTNDDQTMC-----LDINECERDACGNGTCR 1906
Score = 36.3 bits (80), Expect = 0.43
Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 15/93 (16%)
Query: 18 LCVGERCVDTDQGFRCERCP-GSQTSD-GQTCR--TACSANP--CFGGRVPCQDLPDGRY 71
LC G C++T F C +CP G + ++ Q C CS P C GG C + Y
Sbjct: 256 LCQGGNCINTVGSFEC-KCPAGHKLNEVSQKCEDIDECSTIPGICEGGE--CTNTVSS-Y 311
Query: 72 QCGKCPSGFH--GNGVECYRISCRANTCFQGVS 102
C KCP GF+ +G C I R C+ ++
Sbjct: 312 FC-KCPPGFYTSPDGTRC--IDVRPGYCYTALT 341
Score = 35.9 bits (79), Expect = 0.57
Identities = 70/302 (23%), Positives = 110/302 (36%), Gaps = 47/302 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSD--GQTCRTACSANPCFGGRVPCQD--LP-DGRYQ 72
+C CV+T F+C+ CP T D G+ C CF R ++ LP GR++
Sbjct: 920 VCKNGLCVNTRGSFKCQ-CPSGMTLDATGRICLDI-RLETCFL-RYEDEECTLPIAGRHR 976
Query: 73 CGKC--PSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVC 130
C G EC R ++ + + K + + D +C+ +
Sbjct: 977 MDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIP 1036
Query: 131 DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGY--TCVDMDECDLIRPCDDLVSCRNE 188
C +C ++T ++C C SG+ + C D+DEC + C N
Sbjct: 1037 SL---C-THGKC--RNTIGSFKCR-CDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 1089
Query: 189 EXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNP 248
+G+ ++C+D+DEC C RG +C NT
Sbjct: 1090 PGDFECKC-------DEGYES--GFMMMKNCMDIDECQRDPLLC-RGGVCHNT------- 1132
Query: 249 VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPS--YCRRFNAVCGFGQ-KCVCNT 305
+GSY C GH C D + C+ S C V G+ +C CN
Sbjct: 1133 ----EGSYRCECPPGHQLSPNISACID----INECELSAHLCPNGRCVNLIGKYQCACNP 1184
Query: 306 GW 307
G+
Sbjct: 1185 GY 1186
>AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 69.3 bits (162), Expect = 5e-11
Identities = 56/171 (32%), Positives = 69/171 (40%), Gaps = 15/171 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G CVD + GFRC PGS C+ PC G C D P G ++C C G+
Sbjct: 669 GGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHG--ICYDAPGG-FRC-VCEPGW 724
Query: 81 HGN--GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD-AQKPCG 137
G R +C + C G +C G C +CP G GRQC+ + PC
Sbjct: 725 SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHC-TCPPGV--QGRQCELLSPCTPNPCE 781
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
RC +S CP G W G C D+DEC PC C N
Sbjct: 782 HGGRC--ESAPGQLPVCSCPQG--WQGPRCQQDVDECAGPAPCGPHGICTN 828
Score = 63.7 bits (148), Expect = 2e-09
Identities = 56/167 (33%), Positives = 72/167 (43%), Gaps = 21/167 (12%)
Query: 19 CV-GERCVDTDQGFRCERCPGSQTSDGQTCR---TACSANPCFGGRVPCQDLPDGRYQCG 74
CV G C D GF C CP G TC+ C++ PC G C D PDG Y+C
Sbjct: 478 CVNGGVCKDRVNGFSC-TCPSG--FSGSTCQLDVDECASTPCRNG-AKCVDQPDG-YEC- 531
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQ 133
+C GF G + C + C G C + C +C GY G + Q C +Q
Sbjct: 532 RCAEGFEGTLCDRNVDDCSPDPCHHG-RCVDGIASFSC-ACAPGYTGTRCESQVDECRSQ 589
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPC 179
PC +C+ Y C CPSG G C V++D+C PC
Sbjct: 590 -PCRHGGKCL--DLVDKYLCR-CPSG--TTGVNCEVNIDDC-ASNPC 629
Score = 62.9 bits (146), Expect = 4e-09
Identities = 47/153 (30%), Positives = 60/153 (39%), Gaps = 16/153 (10%)
Query: 26 DTDQGFRCERCPGSQTSDGQTCRTACSANPC-FGGRVPCQDLPDG--RYQCGKCPSGFHG 82
D GFRC G QT + C + PC GG+ P G + C C F G
Sbjct: 1225 DPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTC-HCAQPFWG 1283
Query: 83 NGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTG--------YVGDGRQCQHVCDAQK 134
E SCR C GV C++T GP+C +CP G + G + A
Sbjct: 1284 PRCERVARSCRELQCPVGVPCQQTPRGPRC-ACPPGLSGPSCRSFPGSPPGASNASCAAA 1342
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC 167
PC C P +P++ C C G W G C
Sbjct: 1343 PCLHGGSCRPAPLAPFFRC-ACAQG--WTGPRC 1372
Score = 60.5 bits (140), Expect = 2e-08
Identities = 46/154 (29%), Positives = 70/154 (45%), Gaps = 14/154 (9%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHG 82
RCV+T F C+ G +T C + PC + C D G++ C C +GF G
Sbjct: 407 RCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPC-RNQATCLD-RIGQFTC-ICMAGFTG 463
Query: 83 NGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRER 140
E C+++ C G C++ G C +CP+G+ G CQ D A PC
Sbjct: 464 TYCEVDIDECQSSPCVNGGVCKDRVNGFSC-TCPSGF--SGSTCQLDVDECASTPCRNGA 520
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
+C+ + YEC C G++ G C ++D+C
Sbjct: 521 KCVDQPDG--YECR-CAEGFE--GTLCDRNVDDC 549
Score = 58.0 bits (134), Expect = 1e-07
Identities = 81/307 (26%), Positives = 107/307 (34%), Gaps = 52/307 (16%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQD---LPDGRYQCGKCP 77
G RC CP + C + PC GR CQ R+ C +CP
Sbjct: 52 GGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPC-AGRGVCQSSVVAGTARFSC-RCP 109
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ---HVCDAQK 134
GF G C ++ C G C G SCP GY GR C+ C +
Sbjct: 110 RGFRGPDCSLPD-PCLSSPCAHGARCSVGPDGRFLCSCPPGY--QGRSCRSDVDECRVGE 166
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXX 194
PC C+ +T + C+ CP+GY G C E + PC CRN
Sbjct: 167 PCRHGGTCL--NTPGSFRCQ-CPAGY--TGPLC----ENPAV-PCAP-SPCRNGGTCRQS 215
Query: 195 XXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQG 254
G+ G E V+VD+C R C G CV+
Sbjct: 216 GDLTYDCACLPGFEGQNCE------VNVDDCPGHR--CLNGGTCVDG-----------VN 256
Query: 255 SYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRR----FNAVCGFGQKCVCNTGWTGN 310
+Y C C + T + C + D + P+ C FN + G CVC GWTG
Sbjct: 257 TYNC-QCPPEW---TGQFCTE-DVDECQLQPNACHNGGTCFNTL--GGHSCVCVNGWTGE 309
Query: 311 GTVCGLD 317
+D
Sbjct: 310 SCSQNID 316
Score = 57.6 bits (133), Expect = 2e-07
Identities = 84/313 (26%), Positives = 118/313 (37%), Gaps = 39/313 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C+D F C G + + C ++PC G V C+D +G + C CPSGF G+
Sbjct: 446 CLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGV-CKDRVNG-FSC-TCPSGFSGS 502
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
+ C + C G C + G +C C G+ +G C D + PC R
Sbjct: 503 TCQLDVDECASTPCRNGAKCVDQPDGYEC-RCAEGF--EGTLCDRNVDDCSPDPC-HHGR 558
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C+ S + C C GY G C +DEC +PC C +
Sbjct: 559 CVDGIAS--FSC-ACAPGY--TGTRCESQVDEC-RSQPCRHGGKCLD-------LVDKYL 605
Query: 201 XXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRL-CVNTPQYPSNPVSSLQ-GSYIC 258
G G E + C + C G R CV P + + P+ +++
Sbjct: 606 CRCPSGTTGVNCEVNIDDCAS-NPCTFGVCRDGINRYDCVCQPGF-TGPLCNVEINECAS 663
Query: 259 VPCG-GHYYV---NTTRPCFDPDSLVKRC-DPSY-CRR---FNAVC---GFGQKCVCNTG 306
PCG G V N R P SL C PS+ C + +C G +CVC G
Sbjct: 664 SPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPG 723
Query: 307 WTGNGTVCGLDRD 319
W+G L RD
Sbjct: 724 WSGPRCSQSLARD 736
Score = 56.0 bits (129), Expect = 5e-07
Identities = 81/298 (27%), Positives = 111/298 (37%), Gaps = 49/298 (16%)
Query: 28 DQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGV-- 85
D + C PG + + + C + C G C D + Y C +CP + G
Sbjct: 217 DLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGT-CVDGVN-TYNC-QCPPEWTGQFCTE 273
Query: 86 ECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD-AQKPCGRERRCMP 144
+ + N C G +C T G C C G+ G+ Q++ D A C C
Sbjct: 274 DVDECQLQPNACHNGGTCFNTLGGHSC-VCVNGWTGESCS-QNIDDCATAVCFHGATCHD 331
Query: 145 KSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXS 204
+ S Y C CP G G C +D+ + PC + C
Sbjct: 332 RVASFY--C-ACPMGK--TGLLC-HLDDACVSNPCHEDAICDTNPVNGRAICTC-----P 380
Query: 205 QGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGH 264
G+ G ++ DVDEC+ G C CVNT QGS++C CG
Sbjct: 381 PGFTGGACDQ------DVDECSIGANPCEHLGRCVNT-----------QGSFLC-QCGRG 422
Query: 265 YYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC--GFGQ-KCVCNTGWTGNGTVCGLDRD 319
Y T P + D V C CR A C GQ C+C G+T GT C +D D
Sbjct: 423 Y----TGPRCETD--VNECLSGPCRN-QATCLDRIGQFTCICMAGFT--GTYCEVDID 471
Score = 56.0 bits (129), Expect = 5e-07
Identities = 49/175 (28%), Positives = 64/175 (36%), Gaps = 16/175 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRT---ACSANP--CFGGRVPCQDLPDGRYQCGK 75
G CVD + C+ CP T GQ C C P C G L G + C
Sbjct: 248 GGTCVDGVNTYNCQ-CPPEWT--GQFCTEDVDECQLQPNACHNGGTCFNTL--GGHSC-V 301
Query: 76 CPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
C +G+ G C CF G +C + C +CP G G C P
Sbjct: 302 CVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYC-ACPMGKTGLLCHLDDAC-VSNP 359
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDL-IRPCDDLVSCRNEE 189
C + C + C CP G+ G D+DEC + PC+ L C N +
Sbjct: 360 CHEDAICDTNPVNGRAICT-CPPGFT-GGACDQDVDECSIGANPCEHLGRCVNTQ 412
Score = 55.2 bits (127), Expect = 9e-07
Identities = 45/142 (31%), Positives = 58/142 (40%), Gaps = 10/142 (7%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPC-FGGRVPCQDLPDGRYQCGKCP 77
C RCVD F C PG + ++ C + PC GG+ C DL D +Y C +CP
Sbjct: 554 CHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGK--CLDLVD-KYLC-RCP 609
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCG 137
SG G E C +N C GV C + C C G+ G + A PCG
Sbjct: 610 SGTTGVNCEVNIDDCASNPCTFGV-CRDGINRYDC-VCQPGFTGPLCNVEINECASSPCG 667
Query: 138 RERRCMPKSTSPYYECEGCPSG 159
C+ + C CP G
Sbjct: 668 EGGSCVDGENG--FRCL-CPPG 686
Score = 47.6 bits (108), Expect = 2e-04
Identities = 45/149 (30%), Positives = 56/149 (37%), Gaps = 14/149 (9%)
Query: 44 GQTCRTACSANPCF-GGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCF-QGV 101
G +PC GGR C LP C CP G+ G + C + C +GV
Sbjct: 37 GAAAPPCLDGSPCANGGR--CTQLPSREAAC-LCPPGWVGERCQL-EDPCHSGPCAGRGV 92
Query: 102 SCEETQYGPKCGSC--PTGYVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSG 159
G SC P G+ G C PC RC + C CP G
Sbjct: 93 CQSSVVAGTARFSCRCPRGFRGPDCSLPDPC-LSSPCAHGARCSVGPDGRFL-CS-CPPG 149
Query: 160 YQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
YQ G +C D+DEC + PC +C N
Sbjct: 150 YQ--GRSCRSDVDECRVGEPCRHGGTCLN 176
Score = 47.2 bits (107), Expect = 2e-04
Identities = 45/167 (26%), Positives = 60/167 (35%), Gaps = 14/167 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D F C PG C +NPC G C D + C CP G+
Sbjct: 861 GGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGT--CTDHV-ASFTC-TCPPGY 916
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C ++CF G +C + C C GY G CQH D +PC
Sbjct: 917 GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSC-LCRPGYT--GAHCQHEADPCLSRPCLH 973
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSC 185
C + P + C S + G C + + +PC + C
Sbjct: 974 GGVC--SAAHPGFRCTCLES---FTGPQCQTLVDWCSRQPCQNGGRC 1015
Score = 43.6 bits (98), Expect = 0.003
Identities = 77/305 (25%), Positives = 104/305 (34%), Gaps = 47/305 (15%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C G+ CE PG + + C++ PC G C DL RY C CP G
Sbjct: 1096 GGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGG-SCIDLV-ARYLC-SCPPGT 1152
Query: 81 HGNGVECYRISC-------RANTCFQGVSCEETQYGPKCGSCPTGYVG-----DGRQCQH 128
G E C C +C + G +C +CP GY G D +C+
Sbjct: 1153 LGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRC-TCPPGYTGLRCEADINECRS 1211
Query: 129 -VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCR 186
C A R C+ + + C C +G+ +G C + C+ +PC CR
Sbjct: 1212 GACHA----AHTRDCL-QDPGGGFRCL-CHAGF--SGPRCQTVLSPCE-SQPCQHGGQCR 1262
Query: 187 NEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADG--RANCPRGRLCVNTPQY 244
+Q + G ER C ++ +C G PRG C P
Sbjct: 1263 --PSPGPGGGLTFTCHCAQPFWGPRCERVARSCREL-QCPVGVPCQQTPRGPRCACPPGL 1319
Query: 245 PSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCN 304
S GS P G PC S C P+ F +C C
Sbjct: 1320 SGPSCRSFPGS----PPGASNASCAAAPCLHGGS----CRPAPLAPF-------FRCACA 1364
Query: 305 TGWTG 309
GWTG
Sbjct: 1365 QGWTG 1369
Score = 42.3 bits (95), Expect = 0.007
Identities = 49/176 (27%), Positives = 69/176 (39%), Gaps = 21/176 (11%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G CVD F C PG + Q C + PC G V C G ++C C F
Sbjct: 936 GGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGV-CSAAHPG-FRC-TCLESF 992
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG---DGRQ--CQHVC----- 130
G + C C G C +T G C CP G+ G D R C+
Sbjct: 993 TGPQCQTLVDWCSRQPCQNGGRCVQT--GAYC-LCPPGWSGRLCDIRSLPCREAAAQIGV 1049
Query: 131 DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCR 186
++ C +C+ + +S Y C CP G + + ++D C L +PC +CR
Sbjct: 1050 RLEQLCQAGGQCVDEDSSHY--CV-CPEG-RTGSHCEQEVDPC-LAQPCQHGGTCR 1100
Score = 41.9 bits (94), Expect = 0.009
Identities = 45/159 (28%), Positives = 60/159 (37%), Gaps = 24/159 (15%)
Query: 28 DQGFRCERCPGS-------QTSDGQTCRT---ACSANPCFGGRVPCQDLPDGRYQCGKCP 77
+ G RCE PG Q G C+ C+ G C +L G + C C
Sbjct: 781 EHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLA-GSFSC-TCH 838
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKP 135
G+ G + C N C G SC++ C SC G+ G +C D P
Sbjct: 839 GGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSC-SCLPGFAGP--RCARDVDECLSNP 895
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
CG C S + C CP GY G+ C D+ +C
Sbjct: 896 CG-PGTCTDHVAS--FTCT-CPPGY--GGFHCEQDLPDC 928
Score = 41.5 bits (93), Expect = 0.011
Identities = 49/183 (26%), Positives = 64/183 (34%), Gaps = 20/183 (10%)
Query: 63 CQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGD 122
C D D + C CP G G+ E C A C G +C G C C GY GD
Sbjct: 1061 CVD-EDSSHYC-VCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMC-ECLPGYNGD 1117
Query: 123 GRQCQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPC 179
C+ D A +PC C+ Y C CP G G C ++ D+C P
Sbjct: 1118 --NCEDDVDECASQPCQHGGSCI--DLVARYLC-SCPPGTL--GVLCEINEDDCGPGPPL 1170
Query: 180 DDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCV 239
D C + G+ G E D++EC G + R C+
Sbjct: 1171 DSGPRCLH-NGTCVDLVGGFRCTCPPGYTGLRCE------ADINECRSGACHAAHTRDCL 1223
Query: 240 NTP 242
P
Sbjct: 1224 QDP 1226
>AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein.
Length = 2281
Score = 69.3 bits (162), Expect = 5e-11
Identities = 56/171 (32%), Positives = 69/171 (40%), Gaps = 15/171 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G CVD + GFRC PGS C+ PC G C D P G ++C C G+
Sbjct: 629 GGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHG--ICYDAPGG-FRC-VCEPGW 684
Query: 81 HGN--GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD-AQKPCG 137
G R +C + C G +C G C +CP G GRQC+ + PC
Sbjct: 685 SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHC-TCPPGV--QGRQCELLSPCTPNPCE 741
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
RC +S CP G W G C D+DEC PC C N
Sbjct: 742 HGGRC--ESAPGQLPVCSCPQG--WQGPRCQQDVDECAGPAPCGPHGICTN 788
Score = 63.7 bits (148), Expect = 2e-09
Identities = 56/167 (33%), Positives = 72/167 (43%), Gaps = 21/167 (12%)
Query: 19 CV-GERCVDTDQGFRCERCPGSQTSDGQTCR---TACSANPCFGGRVPCQDLPDGRYQCG 74
CV G C D GF C CP G TC+ C++ PC G C D PDG Y+C
Sbjct: 438 CVNGGVCKDRVNGFSC-TCPSG--FSGSTCQLDVDECASTPCRNG-AKCVDQPDG-YEC- 491
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQ 133
+C GF G + C + C G C + C +C GY G + Q C +Q
Sbjct: 492 RCAEGFEGTLCDRNVDDCSPDPCHHG-RCVDGIASFSC-ACAPGYTGTRCESQVDECRSQ 549
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPC 179
PC +C+ Y C CPSG G C V++D+C PC
Sbjct: 550 -PCRHGGKCL--DLVDKYLCR-CPSG--TTGVNCEVNIDDC-ASNPC 589
Score = 62.9 bits (146), Expect = 4e-09
Identities = 47/153 (30%), Positives = 60/153 (39%), Gaps = 16/153 (10%)
Query: 26 DTDQGFRCERCPGSQTSDGQTCRTACSANPC-FGGRVPCQDLPDG--RYQCGKCPSGFHG 82
D GFRC G QT + C + PC GG+ P G + C C F G
Sbjct: 1185 DPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTC-HCAQPFWG 1243
Query: 83 NGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTG--------YVGDGRQCQHVCDAQK 134
E SCR C GV C++T GP+C +CP G + G + A
Sbjct: 1244 PRCERVARSCRELQCPVGVPCQQTPRGPRC-ACPPGLSGPSCRSFPGSPPGASNASCAAA 1302
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC 167
PC C P +P++ C C G W G C
Sbjct: 1303 PCLHGGSCRPAPLAPFFRC-ACAQG--WTGPRC 1332
Score = 60.5 bits (140), Expect = 2e-08
Identities = 46/154 (29%), Positives = 70/154 (45%), Gaps = 14/154 (9%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHG 82
RCV+T F C+ G +T C + PC + C D G++ C C +GF G
Sbjct: 367 RCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPC-RNQATCLD-RIGQFTC-ICMAGFTG 423
Query: 83 NGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRER 140
E C+++ C G C++ G C +CP+G+ G CQ D A PC
Sbjct: 424 TYCEVDIDECQSSPCVNGGVCKDRVNGFSC-TCPSGF--SGSTCQLDVDECASTPCRNGA 480
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
+C+ + YEC C G++ G C ++D+C
Sbjct: 481 KCVDQPDG--YECR-CAEGFE--GTLCDRNVDDC 509
Score = 58.0 bits (134), Expect = 1e-07
Identities = 81/307 (26%), Positives = 107/307 (34%), Gaps = 52/307 (16%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQD---LPDGRYQCGKCP 77
G RC CP + C + PC GR CQ R+ C +CP
Sbjct: 12 GGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPC-AGRGVCQSSVVAGTARFSC-RCP 69
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ---HVCDAQK 134
GF G C ++ C G C G SCP GY GR C+ C +
Sbjct: 70 RGFRGPDCSLPD-PCLSSPCAHGARCSVGPDGRFLCSCPPGY--QGRSCRSDVDECRVGE 126
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXX 194
PC C+ +T + C+ CP+GY G C E + PC CRN
Sbjct: 127 PCRHGGTCL--NTPGSFRCQ-CPAGY--TGPLC----ENPAV-PCAP-SPCRNGGTCRQS 175
Query: 195 XXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQG 254
G+ G E V+VD+C R C G CV+
Sbjct: 176 GDLTYDCACLPGFEGQNCE------VNVDDCPGHR--CLNGGTCVDG-----------VN 216
Query: 255 SYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRR----FNAVCGFGQKCVCNTGWTGN 310
+Y C C + T + C + D + P+ C FN + G CVC GWTG
Sbjct: 217 TYNC-QCPPEW---TGQFCTE-DVDECQLQPNACHNGGTCFNTL--GGHSCVCVNGWTGE 269
Query: 311 GTVCGLD 317
+D
Sbjct: 270 SCSQNID 276
Score = 57.6 bits (133), Expect = 2e-07
Identities = 84/313 (26%), Positives = 118/313 (37%), Gaps = 39/313 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C+D F C G + + C ++PC G V C+D +G + C CPSGF G+
Sbjct: 406 CLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGV-CKDRVNG-FSC-TCPSGFSGS 462
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
+ C + C G C + G +C C G+ +G C D + PC R
Sbjct: 463 TCQLDVDECASTPCRNGAKCVDQPDGYEC-RCAEGF--EGTLCDRNVDDCSPDPC-HHGR 518
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C+ S + C C GY G C +DEC +PC C +
Sbjct: 519 CVDGIAS--FSC-ACAPGY--TGTRCESQVDEC-RSQPCRHGGKCLD-------LVDKYL 565
Query: 201 XXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRL-CVNTPQYPSNPVSSLQ-GSYIC 258
G G E + C + C G R CV P + + P+ +++
Sbjct: 566 CRCPSGTTGVNCEVNIDDCAS-NPCTFGVCRDGINRYDCVCQPGF-TGPLCNVEINECAS 623
Query: 259 VPCG-GHYYV---NTTRPCFDPDSLVKRC-DPSY-CRR---FNAVC---GFGQKCVCNTG 306
PCG G V N R P SL C PS+ C + +C G +CVC G
Sbjct: 624 SPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPG 683
Query: 307 WTGNGTVCGLDRD 319
W+G L RD
Sbjct: 684 WSGPRCSQSLARD 696
Score = 56.0 bits (129), Expect = 5e-07
Identities = 81/298 (27%), Positives = 111/298 (37%), Gaps = 49/298 (16%)
Query: 28 DQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGV-- 85
D + C PG + + + C + C G C D + Y C +CP + G
Sbjct: 177 DLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGT-CVDGVN-TYNC-QCPPEWTGQFCTE 233
Query: 86 ECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD-AQKPCGRERRCMP 144
+ + N C G +C T G C C G+ G+ Q++ D A C C
Sbjct: 234 DVDECQLQPNACHNGGTCFNTLGGHSC-VCVNGWTGESCS-QNIDDCATAVCFHGATCHD 291
Query: 145 KSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXS 204
+ S Y C CP G G C +D+ + PC + C
Sbjct: 292 RVASFY--C-ACPMGK--TGLLC-HLDDACVSNPCHEDAICDTNPVNGRAICTC-----P 340
Query: 205 QGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGH 264
G+ G ++ DVDEC+ G C CVNT QGS++C CG
Sbjct: 341 PGFTGGACDQ------DVDECSIGANPCEHLGRCVNT-----------QGSFLC-QCGRG 382
Query: 265 YYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC--GFGQ-KCVCNTGWTGNGTVCGLDRD 319
Y T P + D V C CR A C GQ C+C G+T GT C +D D
Sbjct: 383 Y----TGPRCETD--VNECLSGPCRN-QATCLDRIGQFTCICMAGFT--GTYCEVDID 431
Score = 56.0 bits (129), Expect = 5e-07
Identities = 49/175 (28%), Positives = 64/175 (36%), Gaps = 16/175 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRT---ACSANP--CFGGRVPCQDLPDGRYQCGK 75
G CVD + C+ CP T GQ C C P C G L G + C
Sbjct: 208 GGTCVDGVNTYNCQ-CPPEWT--GQFCTEDVDECQLQPNACHNGGTCFNTL--GGHSC-V 261
Query: 76 CPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
C +G+ G C CF G +C + C +CP G G C P
Sbjct: 262 CVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYC-ACPMGKTGLLCHLDDAC-VSNP 319
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDL-IRPCDDLVSCRNEE 189
C + C + C CP G+ G D+DEC + PC+ L C N +
Sbjct: 320 CHEDAICDTNPVNGRAICT-CPPGFT-GGACDQDVDECSIGANPCEHLGRCVNTQ 372
Score = 55.2 bits (127), Expect = 9e-07
Identities = 45/142 (31%), Positives = 58/142 (40%), Gaps = 10/142 (7%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPC-FGGRVPCQDLPDGRYQCGKCP 77
C RCVD F C PG + ++ C + PC GG+ C DL D +Y C +CP
Sbjct: 514 CHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGK--CLDLVD-KYLC-RCP 569
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCG 137
SG G E C +N C GV C + C C G+ G + A PCG
Sbjct: 570 SGTTGVNCEVNIDDCASNPCTFGV-CRDGINRYDC-VCQPGFTGPLCNVEINECASSPCG 627
Query: 138 RERRCMPKSTSPYYECEGCPSG 159
C+ + C CP G
Sbjct: 628 EGGSCVDGENG--FRCL-CPPG 646
Score = 47.2 bits (107), Expect = 2e-04
Identities = 44/139 (31%), Positives = 55/139 (39%), Gaps = 14/139 (10%)
Query: 54 NPCF-GGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCF-QGVSCEETQYGPK 111
+PC GGR C LP C CP G+ G + C + C +GV G
Sbjct: 7 SPCANGGR--CTQLPSREAAC-LCPPGWVGERCQL-EDPCHSGPCAGRGVCQSSVVAGTA 62
Query: 112 CGSC--PTGYVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-V 168
SC P G+ G C PC RC + C CP GYQ G +C
Sbjct: 63 RFSCRCPRGFRGPDCSLPDPC-LSSPCAHGARCSVGPDGRFL-CS-CPPGYQ--GRSCRS 117
Query: 169 DMDECDLIRPCDDLVSCRN 187
D+DEC + PC +C N
Sbjct: 118 DVDECRVGEPCRHGGTCLN 136
Score = 47.2 bits (107), Expect = 2e-04
Identities = 45/167 (26%), Positives = 60/167 (35%), Gaps = 14/167 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D F C PG C +NPC G C D + C CP G+
Sbjct: 821 GGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGT--CTDHV-ASFTC-TCPPGY 876
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C ++CF G +C + C C GY G CQH D +PC
Sbjct: 877 GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSC-LCRPGYT--GAHCQHEADPCLSRPCLH 933
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSC 185
C + P + C S + G C + + +PC + C
Sbjct: 934 GGVC--SAAHPGFRCTCLES---FTGPQCQTLVDWCSRQPCQNGGRC 975
Score = 43.6 bits (98), Expect = 0.003
Identities = 77/305 (25%), Positives = 104/305 (34%), Gaps = 47/305 (15%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C G+ CE PG + + C++ PC G C DL RY C CP G
Sbjct: 1056 GGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGG-SCIDLV-ARYLC-SCPPGT 1112
Query: 81 HGNGVECYRISC-------RANTCFQGVSCEETQYGPKCGSCPTGYVG-----DGRQCQH 128
G E C C +C + G +C +CP GY G D +C+
Sbjct: 1113 LGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRC-TCPPGYTGLRCEADINECRS 1171
Query: 129 -VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCR 186
C A R C+ + + C C +G+ +G C + C+ +PC CR
Sbjct: 1172 GACHA----AHTRDCL-QDPGGGFRCL-CHAGF--SGPRCQTVLSPCE-SQPCQHGGQCR 1222
Query: 187 NEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADG--RANCPRGRLCVNTPQY 244
+Q + G ER C ++ +C G PRG C P
Sbjct: 1223 --PSPGPGGGLTFTCHCAQPFWGPRCERVARSCREL-QCPVGVPCQQTPRGPRCACPPGL 1279
Query: 245 PSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCN 304
S GS P G PC S C P+ F +C C
Sbjct: 1280 SGPSCRSFPGS----PPGASNASCAAAPCLHGGS----CRPAPLAPF-------FRCACA 1324
Query: 305 TGWTG 309
GWTG
Sbjct: 1325 QGWTG 1329
Score = 42.3 bits (95), Expect = 0.007
Identities = 49/176 (27%), Positives = 69/176 (39%), Gaps = 21/176 (11%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G CVD F C PG + Q C + PC G V C G ++C C F
Sbjct: 896 GGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGV-CSAAHPG-FRC-TCLESF 952
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG---DGRQ--CQHVC----- 130
G + C C G C +T G C CP G+ G D R C+
Sbjct: 953 TGPQCQTLVDWCSRQPCQNGGRCVQT--GAYC-LCPPGWSGRLCDIRSLPCREAAAQIGV 1009
Query: 131 DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCR 186
++ C +C+ + +S Y C CP G + + ++D C L +PC +CR
Sbjct: 1010 RLEQLCQAGGQCVDEDSSHY--CV-CPEG-RTGSHCEQEVDPC-LAQPCQHGGTCR 1060
Score = 41.9 bits (94), Expect = 0.009
Identities = 45/159 (28%), Positives = 60/159 (37%), Gaps = 24/159 (15%)
Query: 28 DQGFRCERCPGS-------QTSDGQTCRT---ACSANPCFGGRVPCQDLPDGRYQCGKCP 77
+ G RCE PG Q G C+ C+ G C +L G + C C
Sbjct: 741 EHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLA-GSFSC-TCH 798
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKP 135
G+ G + C N C G SC++ C SC G+ G +C D P
Sbjct: 799 GGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSC-SCLPGFAGP--RCARDVDECLSNP 855
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
CG C S + C CP GY G+ C D+ +C
Sbjct: 856 CG-PGTCTDHVAS--FTCT-CPPGY--GGFHCEQDLPDC 888
Score = 41.5 bits (93), Expect = 0.011
Identities = 49/183 (26%), Positives = 64/183 (34%), Gaps = 20/183 (10%)
Query: 63 CQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGD 122
C D D + C CP G G+ E C A C G +C G C C GY GD
Sbjct: 1021 CVD-EDSSHYC-VCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMC-ECLPGYNGD 1077
Query: 123 GRQCQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPC 179
C+ D A +PC C+ Y C CP G G C ++ D+C P
Sbjct: 1078 --NCEDDVDECASQPCQHGGSCI--DLVARYLC-SCPPGTL--GVLCEINEDDCGPGPPL 1130
Query: 180 DDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCV 239
D C + G+ G E D++EC G + R C+
Sbjct: 1131 DSGPRCLH-NGTCVDLVGGFRCTCPPGYTGLRCE------ADINECRSGACHAAHTRDCL 1183
Query: 240 NTP 242
P
Sbjct: 1184 QDP 1186
>AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein.
Length = 2871
Score = 69.3 bits (162), Expect = 5e-11
Identities = 81/275 (29%), Positives = 109/275 (39%), Gaps = 47/275 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRT---ACS--ANPCFGGRVPCQDLPDGRYQ 72
+C+ C +T F C G G+T T C A+ C G C + G ++
Sbjct: 1290 ICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNC-GKHAVCTNTA-GSFK 1347
Query: 73 CGKCPSGFHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV 129
C C G+ G+G++C + C T C Q C+ T +C C GY GDG C +
Sbjct: 1348 CS-CSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRC-LCKEGYTGDGFTCTDL 1405
Query: 130 CDAQKP---CGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLIRPCDDLVS 184
+ + CG + C+ + Y CE C G+ +G C D+DEC L C +
Sbjct: 1406 DECSENLNLCGNGQ-CL--NAPGGYRCE-CDMGFVPSADGKACEDIDECSLPNIC-VFGT 1460
Query: 185 CRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQY 244
C N G GN C DV+EC D C G CVNTP
Sbjct: 1461 CHNLPGLFRCECEIGYELDRSG----GN------CTDVNECLD-PTTCISGN-CVNTP-- 1506
Query: 245 PSNPVSSLQGSYICVPCGGHYYVNTTR-PCFDPDS 278
GSYIC C + +N TR C D S
Sbjct: 1507 ---------GSYIC-DCPPDFELNPTRVGCVDTRS 1531
Score = 67.3 bits (157), Expect = 2e-10
Identities = 53/169 (31%), Positives = 76/169 (44%), Gaps = 21/169 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTS-DGQTCRTA--CSANP--CFGGRVPCQDLPDGRYQ 72
+C G +C + +RC G S D +TC C NP C G C++ G +
Sbjct: 1248 ICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGT--CENTK-GSFI 1304
Query: 73 CGKCPSGFHGNGVE--CYRIS-CR--ANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ 127
C C G+ G + C I+ C A+ C + C T KC SC G++GDG +C
Sbjct: 1305 C-HCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKC-SCSPGWIGDGIKCT 1362
Query: 128 HVCDAQKP---CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC 173
+ + C + C K+T Y C C GY +G+TC D+DEC
Sbjct: 1363 DLDECSNGTHMCSQHADC--KNTMGSYRCL-CKEGYTGDGFTCTDLDEC 1408
Score = 66.5 bits (155), Expect = 4e-10
Identities = 86/336 (25%), Positives = 132/336 (39%), Gaps = 56/336 (16%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDG-QTC----RTACSANPCFGGRVPCQDLPDGRYQ 72
LC G C +T+ +RCE PG Q S C SA+ C GR C +L G+YQ
Sbjct: 1123 LCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGR--CVNL-IGKYQ 1179
Query: 73 CGKCPSGFHGNGVECYRISCRANTCFQG---VSCEETQYGPKCGSCPTGY--VGDGRQCQ 127
C C G+H + + + G C ++ +C SC G+ + D R C
Sbjct: 1180 CA-CNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYEC-SCQPGFALMPDQRSCT 1237
Query: 128 HV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLIRPCDDLV 183
+ C+ +C + Y C C G+ + TCVD++ECDL
Sbjct: 1238 DIDECEDNPNICDGGQC--TNIPGEYRCL-CYDGFMASEDMKTCVDVNECDLNPNICLSG 1294
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQ 243
+C N + G+ G ++ + C D++EC G NC + +C NT
Sbjct: 1295 TCENTK-------GSFICHCDMGYSG---KKGKTGCTDINECEIGAHNCGKHAVCTNT-- 1342
Query: 244 YPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSL---VKRCDP-SYCRRFNAVCGFGQ 299
GS+ C G ++ C D D C + C+ N + +
Sbjct: 1343 ---------AGSFKCSCSPG--WIGDGIKCTDLDECSNGTHMCSQHADCK--NTMGSY-- 1387
Query: 300 KCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRC 335
+C+C G+TG+G C DLD + C +C
Sbjct: 1388 RCLCKEGYTGDGFTC---TDLDECSENLNLCGNGQC 1420
Score = 64.5 bits (150), Expect = 1e-09
Identities = 56/167 (33%), Positives = 75/167 (44%), Gaps = 18/167 (10%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTC--RTACS-ANPCFGGRVPCQDLPDGRYQCG 74
+C +C++TD +RCE CP G C CS NPC G C+++ G ++C
Sbjct: 2136 VCKHGQCINTDGSYRCE-CPFGYILAGNECVDTDECSVGNPC--GNGTCKNVIGG-FEC- 2190
Query: 75 KCPSGFH-GNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQC--QH 128
C GF G + C I+ C N C T YG CP GYV D R C +
Sbjct: 2191 TCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNT-YGSYECKCPVGYVLREDRRMCKDED 2249
Query: 129 VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDEC 173
C+ K E++ K+ Y C C GYQ +G CVD +EC
Sbjct: 2250 ECEEGKHDCTEKQMECKNLIGTYMCI-CGPGYQRRPDGEGCVDENEC 2295
Score = 55.6 bits (128), Expect = 7e-07
Identities = 67/234 (28%), Positives = 89/234 (38%), Gaps = 31/234 (13%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQT-CR--TACSANPCFGGRVPCQDLPDGRYQCG 74
+C +C+DT F C G +T+D QT C C + C G C++ G + C
Sbjct: 1859 ICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGT--CRNTI-GSFNC- 1914
Query: 75 KCPSGF---HGNGV----ECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQ 125
+C GF H N EC S N C G C T +C C GY DGR
Sbjct: 1915 RCNHGFILSHNNDCIDVDEC--ASGNGNLCRNG-QCINTVGSFQC-QCNEGYEVAPDGRT 1970
Query: 126 CQHVCDAQKPCGRERRCMP---KSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDL 182
C D + R+C P ++ Y C CP GY C D+DEC L
Sbjct: 1971 C---VDINECLLEPRKCAPGTCQNLDGSYRCI-CPPGYSLQNEKCEDIDECVEEPEICAL 2026
Query: 183 VSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGR 236
+C N E S G R + R +C E G+ + P+ R
Sbjct: 2027 GTCSNTEGSFKCLCPEGFSLSSSGRR--CQDLRMSYCYAKFE--GGKCSSPKSR 2076
Score = 54.0 bits (124), Expect = 2e-06
Identities = 65/230 (28%), Positives = 95/230 (41%), Gaps = 33/230 (14%)
Query: 24 CVDTDQGFRCERCPGSQ-TSDGQ-TCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
C++T +RC+ PG + TS GQ R C P C D G + C C +GF
Sbjct: 1824 CINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTV-GSFYC-LCHTGFK 1881
Query: 82 GNGVE--CYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGYV-GDGRQCQHVCDAQKPCG 137
N + C I+ C + C G +C T C C G++ C V + G
Sbjct: 1882 TNDDQTMCLDINECERDACGNG-TCRNTIGSFNC-RCNHGFILSHNNDCIDVDECASGNG 1939
Query: 138 ---RERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDL-IRPCDDLVSCRNEEXX 191
R +C+ +T ++C+ C GY+ +G TCVD++EC L R C +C+N +
Sbjct: 1940 NLCRNGQCI--NTVGSFQCQ-CNEGYEVAPDGRTCVDINECLLEPRKCAP-GTCQNLDGS 1995
Query: 192 XXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNT 241
G + E C D+DEC + C G C NT
Sbjct: 1996 YRCIC------------PPGYSLQNEKCEDIDECVEEPEICALG-TCSNT 2032
Score = 51.2 bits (117), Expect = 1e-05
Identities = 82/314 (26%), Positives = 113/314 (35%), Gaps = 51/314 (16%)
Query: 18 LCVGERCVDTDQGFRCERCPG-SQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKC 76
LC RCV+ ++C PG T D C + GG +G Y+C C
Sbjct: 1165 LCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECS-C 1223
Query: 77 PSGFH--GNGVECYRIS-CRAN-TCFQGVSCEETQYGPKCGSCPTGYVG--DGRQCQHV- 129
GF + C I C N G C +C C G++ D + C V
Sbjct: 1224 QPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRC-LCYDGFMASEDMKTCVDVN 1282
Query: 130 -CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN-GYT-CVDMDECDL-IRPCDDLVSC 185
CD C ++T + C C GY G T C D++EC++ C C
Sbjct: 1283 ECDLNPNICLSGTC--ENTKGSFICH-CDMGYSGKKGKTGCTDINECEIGAHNCGKHAVC 1339
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
N S GW G G + C D+DEC++G C + C NT
Sbjct: 1340 TN-------TAGSFKCSCSPGWIGDGIK-----CTDLDECSNGTHMCSQHADCKNT---- 1383
Query: 246 SNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSL---VKRCDPSYCRRFNAVCGFGQKCV 302
GSY C+ G Y C D D + C C NA G+ +C
Sbjct: 1384 -------MGSYRCLCKEG--YTGDGFTCTDLDECSENLNLCGNGQC--LNAPGGY--RCE 1430
Query: 303 CNTGW--TGNGTVC 314
C+ G+ + +G C
Sbjct: 1431 CDMGFVPSADGKAC 1444
Score = 51.2 bits (117), Expect = 1e-05
Identities = 69/282 (24%), Positives = 108/282 (38%), Gaps = 54/282 (19%)
Query: 69 GRYQCGKCPSGFHGNG--VECYRIS-CRAN-TCFQGVSCEETQYGPKCGSCP------TG 118
G ++C +CP GF N + C I C+ C + C T +C P TG
Sbjct: 1787 GSFRC-ECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTG 1845
Query: 119 YVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLI 176
D +CQ + + C + C+ S Y C +G++ N C+D++EC+
Sbjct: 1846 QCNDRNECQEIPNI---CSHGQ-CIDTVGSFYCLCH---TGFKTNDDQTMCLDINECE-- 1896
Query: 177 RPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGR 236
R +CRN + G+ + N C+DVDECA G N R
Sbjct: 1897 RDACGNGTCRN-------TIGSFNCRCNHGFILSHNN----DCIDVDECASGNGNLCRNG 1945
Query: 237 LCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLV---KRCDPSYCRRFNA 293
C+NT GS+ C G+ R C D + + ++C P C+ +
Sbjct: 1946 QCINT-----------VGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDG 1994
Query: 294 VCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRC 335
+C+C G++ C D+D +E C C
Sbjct: 1995 ----SYRCICPPGYSLQNEKC---EDIDECVEEPEICALGTC 2029
Score = 50.4 bits (115), Expect = 2e-05
Identities = 53/189 (28%), Positives = 72/189 (38%), Gaps = 27/189 (14%)
Query: 8 DAGSMVTPFKLCVGERCVDTDQGFRCERCPGSQTS-DGQTCRTACSANPCFGGRVPCQDL 66
D TP +C+ RCV+TD +RCE PG DG+ C + C+GG
Sbjct: 613 DINECETP-GICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGG------- 664
Query: 67 PDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCE------ETQYGPKCGSCPTGYV 120
Y+ G+C G V C + G C+ +Y C S P G
Sbjct: 665 ----YKRGQCIKPLFG-AVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGP-GMT 718
Query: 121 GDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN--GYTCVDMDECDLIRP 178
G C C ++ Y+C C SGY+ + G CVD++EC L
Sbjct: 719 SAGSDINE-CALDPDICPNGIC--ENLRGTYKCI-CNSGYEVDSTGKNCVDINECVLNSL 774
Query: 179 CDDLVSCRN 187
D CRN
Sbjct: 775 LCDNGQCRN 783
Score = 49.2 bits (112), Expect = 6e-05
Identities = 76/286 (26%), Positives = 104/286 (36%), Gaps = 53/286 (18%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQ-TSDGQTCR--TACSA-NPCFGGRVPCQDLPDGRYQC 73
+C+ C++ D F+C PG Q SDG+ C+ C C GR C + DG Y+C
Sbjct: 581 MCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGR--CVNT-DGSYRC 637
Query: 74 GKCPSGFHG-NGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVC-D 131
P G +G C R+ TC+ G K G C G + + C
Sbjct: 638 ECFPGLAVGLDGRVCVDTHMRS-TCYGGY---------KRGQCIKPLFGAVTKSECCCAS 687
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV--DMDECDLIRPCDDLVSCRNEE 189
+ G + P S Y+ C SG G T D++EC L C N
Sbjct: 688 TEYAFGEPCQPCPAQNSAEYQAL-CSSG---PGMTSAGSDINECALDPDICPNGICENLR 743
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPV 249
S G ++CVD++EC C G+ C NTP
Sbjct: 744 GTYKCICNSGYEVDSTG----------KNCVDINECVLNSLLCDNGQ-CRNTP------- 785
Query: 250 SSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC 295
GS++C G Y + C D D C+ S C N VC
Sbjct: 786 ----GSFVCTCPKGFIYKPDLKTCEDID----ECESSPC--INGVC 821
Score = 48.8 bits (111), Expect = 8e-05
Identities = 51/170 (30%), Positives = 70/170 (41%), Gaps = 23/170 (13%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGK 75
LC RC+ T RCE G Q C C NPC GG C + G Y C +
Sbjct: 459 LCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGGE--CIN-NQGSYTC-Q 514
Query: 76 CPSGFHG--NGVECYRI-SCRAN--TCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQH 128
C +G+ EC I C N C G C T C C G+ DG+ C+
Sbjct: 515 CRAGYQSTLTRTECRDIDECLQNGRICNNG-RCINTDGSFHC-VCNAGFHVTRDGKNCED 572
Query: 129 V--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECD 174
+ C + C C+ + S ++C C G+Q +G C D++EC+
Sbjct: 573 MDECSIRNMC-LNGMCINEDGS--FKCI-CKPGFQLASDGRYCKDINECE 618
Score = 46.0 bits (104), Expect = 5e-04
Identities = 80/305 (26%), Positives = 111/305 (36%), Gaps = 56/305 (18%)
Query: 22 ERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCF--GGR---VPCQDLP-DGRYQCGK 75
+ C+D +G+ + G + R + + C GGR C+ P G K
Sbjct: 2329 DECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKK 2388
Query: 76 -CPSG--FHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGD--GRQCQHV- 129
CP G F NG + + C G C + C C TGY D G C +
Sbjct: 2389 LCPHGRGFMTNGADIDECKVIHDVCRNG-ECVNDRGSYHC-ICKTGYTPDITGTSCVDLN 2446
Query: 130 -CD-AQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLIRP-CDDLVS 184
C+ A KPC + K+T Y+C CP GY Q +G +C D+DEC + C L
Sbjct: 2447 ECNQAPKPCN----FICKNTEGSYQCS-CPKGYILQEDGRSCKDLDECATKQHNCQFL-- 2499
Query: 185 CRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQY 244
C N G + C+D +EC C +C NTP
Sbjct: 2500 CVNTIGGFTCKCP------------PGFTQHHTSCIDNNECTSDINLCGSKGICQNTP-- 2545
Query: 245 PSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLV--KRCDPSYCRRFNAVCGFGQKCV 302
GS+ C G T C D D RC C+ N + G+ +C
Sbjct: 2546 ---------GSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHG-CQ--NIIGGY--RCS 2591
Query: 303 CNTGW 307
C G+
Sbjct: 2592 CPQGY 2596
Score = 43.6 bits (98), Expect = 0.003
Identities = 51/179 (28%), Positives = 69/179 (38%), Gaps = 36/179 (20%)
Query: 141 RCMPKSTSPYYECEGCPSGYQWN-GYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXX 199
RC+P S CE C G+Q + C+D+DEC+ PC C N +
Sbjct: 464 RCIPTPGS--CRCE-CNKGFQLDLRGECIDVDECEK-NPCAG-GECINNQGSYTCQCRA- 517
Query: 200 XXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICV 259
G++ T R C D+DEC C GR C+NT GS+ CV
Sbjct: 518 ------GYQST---LTRTECRDIDECLQNGRICNNGR-CINT-----------DGSFHCV 556
Query: 260 PCGGHYYVNTTRPCFDPD--SLVKRCDPSYCRRFNAVCGFGQKCVCNTGW--TGNGTVC 314
G + + C D D S+ C C N F KC+C G+ +G C
Sbjct: 557 CNAGFHVTRDGKNCEDMDECSIRNMCLNGMC--INEDGSF--KCICKPGFQLASDGRYC 611
Score = 43.6 bits (98), Expect = 0.003
Identities = 57/222 (25%), Positives = 81/222 (36%), Gaps = 37/222 (16%)
Query: 95 NTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKPCGRERRCMPKSTSPYYE 152
+ C G C T +C CP GY+ G +C C PCG C K+ +E
Sbjct: 2135 DVCKHG-QCINTDGSYRC-ECPFGYILAGNECVDTDECSVGNPCGNGT-C--KNVIGGFE 2189
Query: 153 CEGCPSGYQWNGY-TCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTG 211
C C G++ TC D++EC P C N G
Sbjct: 2190 CT-CEEGFEPGPMMTCEDINECAQ-NPLLCAFRCVNTYGSYECKCPV----------GYV 2237
Query: 212 NERRREHCVDVDECADGRANCPRGRL-CVNTPQYPSNPVSSLQGSYICVPCG-GHYYVNT 269
R C D DEC +G+ +C ++ C N L G+Y+C+ CG G+
Sbjct: 2238 LREDRRMCKDEDECEEGKHDCTEKQMECKN-----------LIGTYMCI-CGPGYQRRPD 2285
Query: 270 TRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCNTGWTGN 310
C D + + P C + G C CN G+T +
Sbjct: 2286 GEGCVDENEC--QTKPGICENGRCLNTRGSYTCECNDGFTAS 2325
Score = 43.2 bits (97), Expect = 0.004
Identities = 40/119 (33%), Positives = 51/119 (42%), Gaps = 14/119 (11%)
Query: 17 KLCVGERCVDTDQGFRCERCPGSQ-TSDGQTCR--TACS-ANPCFGGRVPCQDLPDGRYQ 72
++C RC++TD F C G T DG+ C CS N C G C + DG ++
Sbjct: 539 RICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGM--CIN-EDGSFK 595
Query: 73 CGKCPSGFH--GNGVECYRIS-CRA-NTCFQGVSCEETQYGPKCGSCPTGYVG-DGRQC 126
C C GF +G C I+ C C G C T +C P VG DGR C
Sbjct: 596 C-ICKPGFQLASDGRYCKDINECETPGICMNG-RCVNTDGSYRCECFPGLAVGLDGRVC 652
Score = 43.2 bits (97), Expect = 0.004
Identities = 52/192 (27%), Positives = 79/192 (41%), Gaps = 33/192 (17%)
Query: 8 DAGSMVTPFKLCVGERCVDTDQGFRCERCPG--SQTSDGQTCRTACSANPCFGGRVPCQD 65
D V ++C C +T+ F+C CP S +S G+ C+ + C+
Sbjct: 2013 DIDECVEEPEICALGTCSNTEGSFKC-LCPEGFSLSSSGRRCQDL-RMSYCYA------- 2063
Query: 66 LPDGRYQCGKC--PSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGS---CPTG-- 118
+++ GKC P + + EC C G CE P CP G
Sbjct: 2064 ----KFEGGKCSSPKSRNHSKQEC---CCALKGEGWGDPCELCPTEPDEAFRQICPYGSG 2116
Query: 119 -YVGDGRQCQHVCDAQKP--CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDL 175
VG + + ++P C + +C+ +T Y CE CP GY G CVD DEC +
Sbjct: 2117 IIVGPDDSAVDMDECKEPDVC-KHGQCI--NTDGSYRCE-CPFGYILAGNECVDTDECSV 2172
Query: 176 IRPCDDLVSCRN 187
PC + +C+N
Sbjct: 2173 GNPCGN-GTCKN 2183
Score = 41.5 bits (93), Expect = 0.011
Identities = 86/335 (25%), Positives = 123/335 (36%), Gaps = 60/335 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPC----FGGRVPCQDLPDGRYQC 73
LC G +C++T F+C RCP + T R N C G C + G Y C
Sbjct: 1616 LCQGGKCINTFGSFQC-RCPTGYYLNEDT-RVCDDVNECETPGICGPGTCYNTV-GNYTC 1672
Query: 74 GKCPSGFHGNG----VECYRISCRANTCFQGVSCE-ETQYGPKCGSCPTGYVGDGRQCQH 128
P NG ++ R C N +C+ E + C Y GR
Sbjct: 1673 ICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSY-NIGRAWN- 1730
Query: 129 VCDAQKPCGRERRCMPKSTSPYYE-CEGCPSGYQWNGYTC--VDMDEC-DLIRPCDDLVS 184
KPC +C ST + C G+ + YT VD+DEC ++ C++ V
Sbjct: 1731 -----KPC---EQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGV- 1781
Query: 185 CRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQY 244
C N + G + C D+DEC +G C R C+NT
Sbjct: 1782 CIN----------MVGSFRCECPVGFFYNDKLLVCEDIDECQNGPV-CQRNAECINT--- 1827
Query: 245 PSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVC 303
GSY C C Y +T C D + + P+ C + G C+C
Sbjct: 1828 --------AGSYRC-DCKPGYRFTSTGQCNDRNECQE--IPNICSHGQCIDTVGSFYCLC 1876
Query: 304 NTGWTGNG--TVCGLDRDLDGHPDEQLPCNEPRCK 336
+TG+ N T+C LD + E+ C C+
Sbjct: 1877 HTGFKTNDDQTMC-----LDINECERDACGNGTCR 1906
Score = 40.3 bits (90), Expect = 0.026
Identities = 54/194 (27%), Positives = 75/194 (38%), Gaps = 30/194 (15%)
Query: 56 CFGGRVPCQDLPDGRYQCGKCPSGFHGN-GVECYRIS-CRANTCFQGVSCEETQYGPKCG 113
C GR C P G +C +C GF + EC + C N C G C Q C
Sbjct: 460 CQNGR--CIPTP-GSCRC-ECNKGFQLDLRGECIDVDECEKNPCAGG-ECINNQGSYTC- 513
Query: 114 SCPTGYVGD--GRQCQHV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTC 167
C GY +C+ + C RC+ +T + C C +G+ +G C
Sbjct: 514 QCRAGYQSTLTRTECRDIDECLQNGRICNNGRCI--NTDGSFHCV-CNAGFHVTRDGKNC 570
Query: 168 VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECAD 227
DMDEC + C + + C NE+ S G +C D++EC +
Sbjct: 571 EDMDECSIRNMCLNGM-CINEDGSFKCICKPGFQLASDG----------RYCKDINEC-E 618
Query: 228 GRANCPRGRLCVNT 241
C GR CVNT
Sbjct: 619 TPGICMNGR-CVNT 631
Score = 36.3 bits (80), Expect = 0.43
Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 15/93 (16%)
Query: 18 LCVGERCVDTDQGFRCERCP-GSQTSD-GQTCR--TACSANP--CFGGRVPCQDLPDGRY 71
LC G C++T F C +CP G + ++ Q C CS P C GG C + Y
Sbjct: 256 LCQGGNCINTVGSFEC-KCPAGHKLNEVSQKCEDIDECSTIPGICEGGE--CTNTVSS-Y 311
Query: 72 QCGKCPSGFH--GNGVECYRISCRANTCFQGVS 102
C KCP GF+ +G C I R C+ ++
Sbjct: 312 FC-KCPPGFYTSPDGTRC--IDVRPGYCYTALT 341
Score = 35.9 bits (79), Expect = 0.57
Identities = 70/302 (23%), Positives = 110/302 (36%), Gaps = 47/302 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSD--GQTCRTACSANPCFGGRVPCQD--LP-DGRYQ 72
+C CV+T F+C+ CP T D G+ C CF R ++ LP GR++
Sbjct: 920 VCKNGLCVNTRGSFKCQ-CPSGMTLDATGRICLDI-RLETCFL-RYEDEECTLPIAGRHR 976
Query: 73 CGKC--PSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVC 130
C G EC R ++ + + K + + D +C+ +
Sbjct: 977 MDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIP 1036
Query: 131 DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGY--TCVDMDECDLIRPCDDLVSCRNE 188
C +C ++T ++C C SG+ + C D+DEC + C N
Sbjct: 1037 SL---C-THGKC--RNTIGSFKCR-CDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 1089
Query: 189 EXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNP 248
+G+ ++C+D+DEC C RG +C NT
Sbjct: 1090 PGDFECKC-------DEGYES--GFMMMKNCMDIDECQRDPLLC-RGGVCHNT------- 1132
Query: 249 VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPS--YCRRFNAVCGFGQ-KCVCNT 305
+GSY C GH C D + C+ S C V G+ +C CN
Sbjct: 1133 ----EGSYRCECPPGHQLSPNISACID----INECELSAHLCPNGRCVNLIGKYQCACNP 1184
Query: 306 GW 307
G+
Sbjct: 1185 GY 1186
>U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jagged
protein.
Length = 1214
Score = 68.9 bits (161), Expect = 7e-11
Identities = 54/176 (30%), Positives = 74/176 (42%), Gaps = 16/176 (9%)
Query: 15 PFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCG 74
P CV C + Q CE G Q D + + PC G C + +YQC
Sbjct: 254 PHPGCVHGICNEPWQCL-CETNWGGQLCD-KDLNYCGTHQPCLNGGT-CSNTGPDKYQCS 310
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQK 134
CP G+ G E +C ++ C SC+ET G +C C G+ G C D
Sbjct: 311 -CPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFEC-ECSPGWTGP--TCSTNIDDCS 366
Query: 135 P--CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
P C C ++C CP QW G TC +D +EC+ +PC + SC+N
Sbjct: 367 PNNCSHGGTCQDLVNG--FKCV-CPP--QWTGKTCQLDANECE-AKPCVNAKSCKN 416
Score = 64.9 bits (151), Expect = 1e-09
Identities = 56/170 (32%), Positives = 73/170 (42%), Gaps = 20/170 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C +T GF CE PG G TC T CS N C G CQDL +G ++C CP +
Sbjct: 338 CKETSLGFECECSPGWT---GPTCSTNIDDCSPNNCSHGGT-CQDLVNG-FKC-VCPPQW 391
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQKPCGRE 139
G + C A C SC+ C C G++ G+ C ++ D C +
Sbjct: 392 TGKTCQLDANECEAKPCVNAKSCKNLIASYYC-DCLPGWM--GQNCDININDCLGQCQND 448
Query: 140 RRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSCRNE 188
C + Y C CP GY G C D+DEC PC + C+NE
Sbjct: 449 ASC--RDLVNGYRCI-CPPGYA--GDHCERDIDEC-ASNPCLNGGHCQNE 492
Score = 60.9 bits (141), Expect = 2e-08
Identities = 83/322 (25%), Positives = 112/322 (34%), Gaps = 45/322 (13%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C D G+RC PG + C++NPC G CQ+ R+QC CP+GF GN
Sbjct: 451 CRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGG-HCQN-EINRFQC-LCPTGFSGN 507
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
+ C N C G C C CP Y +G+ C H+ D PC
Sbjct: 508 LCQLDIDYCEPNPCQNGAQCYNRASDYFC-KCPEDY--EGKNCSHLKDHCRTTPCEVIDS 564
Query: 142 CMPKSTSPYYECEGCPSGYQW-NGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C S P G ++ + C +C C N+
Sbjct: 565 CTVAMAS-----NDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDC-NKGFTGTYCHENIN 618
Query: 201 XXXSQGWRGTGNERRREHCVD-VDE----CADG--RANCPRG-RLCVNTPQYPSNPVSSL 252
S R G C+D V+ C+DG A C C P + L
Sbjct: 619 DCESNPCRNGGT------CIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDL 672
Query: 253 QGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQKCVCNTGWTG 309
+ C C + T C DS +CD + C C G KC+C GW
Sbjct: 673 VNDFYC-DCKNGWKGKT---CHSRDS---QCDEATCNN-GGTCYDEGDAFKCMCPGGW-- 722
Query: 310 NGTVCGLDRDLDGHPDEQLPCN 331
GT C + R+ P+ PC+
Sbjct: 723 EGTTCNIARNSSCLPN---PCH 741
Score = 53.6 bits (123), Expect = 3e-06
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 16/169 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C+D ++C G + + +T CS NPC G C+DL + Y C C +G+
Sbjct: 628 GGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGT-CRDLVNDFY-C-DCKNGW 684
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQ---KPCG 137
G C TC G +C + KC CP G+ +G C ++ PC
Sbjct: 685 KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKC-MCPGGW--EGTTCNIARNSSCLPNPCH 741
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSC 185
C+ S + C C G W G C + ++C PC + +C
Sbjct: 742 NGGTCVVNGES--FTCV-CKEG--WEGPICAQNTNDCS-PHPCYNSGTC 784
Score = 51.6 bits (118), Expect = 1e-05
Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 26/166 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
CVD D +RCE PG D + C ++PC G C D +G Y+C CP G +
Sbjct: 784 CVDGDNWYRCECAPGFAGPDCRININECQSSPCAFG-ATCVDEING-YRC-VCPPGH--S 838
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCM 143
G +C +S R V + ++ C +C + C V +PC +
Sbjct: 839 GAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQC--LNGRIACSKVWCGPRPC-----LL 891
Query: 144 PKSTSPYYECEGCPSGYQWNGYTCVDM--DECDLIRPCDDLVSCRN 187
K S CPS G +C+ + D+C + PC + CR+
Sbjct: 892 HKGHSE------CPS-----GQSCIPILDDQC-FVHPCTGVGECRS 925
Score = 32.3 bits (70), Expect = 7.0
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 10/94 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFG-GRVPCQDLPDGRYQCGKCPSG 79
G CVD G+RC PG G C+ S PC G V +PDG C +
Sbjct: 819 GATCVDEINGYRCVCPPG---HSGAKCQEV-SGRPCITMGSV----IPDGAKWDDDCNTC 870
Query: 80 FHGNG-VECYRISCRANTCFQGVSCEETQYGPKC 112
NG + C ++ C C E G C
Sbjct: 871 QCLNGRIACSKVWCGPRPCLLHKGHSECPSGQSC 904
>U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein.
Length = 1218
Score = 68.9 bits (161), Expect = 7e-11
Identities = 54/176 (30%), Positives = 74/176 (42%), Gaps = 16/176 (9%)
Query: 15 PFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCG 74
P CV C + Q CE G Q D + + PC G C + +YQC
Sbjct: 267 PHPGCVHGICNEPWQCL-CETNWGGQLCD-KDLNYCGTHQPCLNGGT-CSNTGPDKYQCS 323
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQK 134
CP G+ G E +C ++ C SC+ET G +C C G+ G C D
Sbjct: 324 -CPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFEC-ECSPGWTGP--TCSTNIDDCS 379
Query: 135 P--CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
P C C ++C CP QW G TC +D +EC+ +PC + SC+N
Sbjct: 380 PNNCSHGGTCQDLVNG--FKCV-CPP--QWTGKTCQLDANECE-AKPCVNAKSCKN 429
Score = 64.9 bits (151), Expect = 1e-09
Identities = 56/170 (32%), Positives = 73/170 (42%), Gaps = 20/170 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C +T GF CE PG G TC T CS N C G CQDL +G ++C CP +
Sbjct: 351 CKETSLGFECECSPGWT---GPTCSTNIDDCSPNNCSHGGT-CQDLVNG-FKC-VCPPQW 404
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQKPCGRE 139
G + C A C SC+ C C G++ G+ C ++ D C +
Sbjct: 405 TGKTCQLDANECEAKPCVNAKSCKNLIASYYC-DCLPGWM--GQNCDININDCLGQCQND 461
Query: 140 RRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSCRNE 188
C + Y C CP GY G C D+DEC PC + C+NE
Sbjct: 462 ASC--RDLVNGYRCI-CPPGYA--GDHCERDIDEC-ASNPCLNGGHCQNE 505
Score = 60.9 bits (141), Expect = 2e-08
Identities = 83/322 (25%), Positives = 112/322 (34%), Gaps = 45/322 (13%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C D G+RC PG + C++NPC G CQ+ R+QC CP+GF GN
Sbjct: 464 CRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGG-HCQN-EINRFQC-LCPTGFSGN 520
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
+ C N C G C C CP Y +G+ C H+ D PC
Sbjct: 521 LCQLDIDYCEPNPCQNGAQCYNRASDYFC-KCPEDY--EGKNCSHLKDHCRTTPCEVIDS 577
Query: 142 CMPKSTSPYYECEGCPSGYQW-NGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C S P G ++ + C +C C N+
Sbjct: 578 CTVAMAS-----NDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDC-NKGFTGTYCHENIN 631
Query: 201 XXXSQGWRGTGNERRREHCVD-VDE----CADG--RANCPRG-RLCVNTPQYPSNPVSSL 252
S R G C+D V+ C+DG A C C P + L
Sbjct: 632 DCESNPCRNGGT------CIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDL 685
Query: 253 QGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQKCVCNTGWTG 309
+ C C + T C DS +CD + C C G KC+C GW
Sbjct: 686 VNDFYC-DCKNGWKGKT---CHSRDS---QCDEATCNN-GGTCYDEGDAFKCMCPGGW-- 735
Query: 310 NGTVCGLDRDLDGHPDEQLPCN 331
GT C + R+ P+ PC+
Sbjct: 736 EGTTCNIARNSSCLPN---PCH 754
Score = 53.6 bits (123), Expect = 3e-06
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 16/169 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C+D ++C G + + +T CS NPC G C+DL + Y C C +G+
Sbjct: 641 GGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGT-CRDLVNDFY-C-DCKNGW 697
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQ---KPCG 137
G C TC G +C + KC CP G+ +G C ++ PC
Sbjct: 698 KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKC-MCPGGW--EGTTCNIARNSSCLPNPCH 754
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSC 185
C+ S + C C G W G C + ++C PC + +C
Sbjct: 755 NGGTCVVNGES--FTCV-CKEG--WEGPICAQNTNDCS-PHPCYNSGTC 797
Score = 51.6 bits (118), Expect = 1e-05
Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 26/166 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
CVD D +RCE PG D + C ++PC G C D +G Y+C CP G +
Sbjct: 797 CVDGDNWYRCECAPGFAGPDCRININECQSSPCAFG-ATCVDEING-YRC-VCPPGH--S 851
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCM 143
G +C +S R V + ++ C +C + C V +PC +
Sbjct: 852 GAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQC--LNGRIACSKVWCGPRPC-----LL 904
Query: 144 PKSTSPYYECEGCPSGYQWNGYTCVDM--DECDLIRPCDDLVSCRN 187
K S CPS G +C+ + D+C + PC + CR+
Sbjct: 905 HKGHSE------CPS-----GQSCIPILDDQC-FVHPCTGVGECRS 938
Score = 32.3 bits (70), Expect = 7.0
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 10/94 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFG-GRVPCQDLPDGRYQCGKCPSG 79
G CVD G+RC PG G C+ S PC G V +PDG C +
Sbjct: 832 GATCVDEINGYRCVCPPG---HSGAKCQEV-SGRPCITMGSV----IPDGAKWDDDCNTC 883
Query: 80 FHGNG-VECYRISCRANTCFQGVSCEETQYGPKC 112
NG + C ++ C C E G C
Sbjct: 884 QCLNGRIACSKVWCGPRPCLLHKGHSECPSGQSC 917
>U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jagged
1 protein.
Length = 1218
Score = 68.9 bits (161), Expect = 7e-11
Identities = 54/176 (30%), Positives = 74/176 (42%), Gaps = 16/176 (9%)
Query: 15 PFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCG 74
P CV C + Q CE G Q D + + PC G C + +YQC
Sbjct: 267 PHPGCVHGICNEPWQCL-CETNWGGQLCD-KDLNYCGTHQPCLNGGT-CSNTGPDKYQCS 323
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQK 134
CP G+ G E +C ++ C SC+ET G +C C G+ G C D
Sbjct: 324 -CPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFEC-ECSPGWTGP--TCSTNIDDCS 379
Query: 135 P--CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
P C C ++C CP QW G TC +D +EC+ +PC + SC+N
Sbjct: 380 PNNCSHGGTCQDLVNG--FKCV-CPP--QWTGKTCQLDANECE-AKPCVNAKSCKN 429
Score = 64.9 bits (151), Expect = 1e-09
Identities = 56/170 (32%), Positives = 73/170 (42%), Gaps = 20/170 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C +T GF CE PG G TC T CS N C G CQDL +G ++C CP +
Sbjct: 351 CKETSLGFECECSPGWT---GPTCSTNIDDCSPNNCSHGGT-CQDLVNG-FKC-VCPPQW 404
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQKPCGRE 139
G + C A C SC+ C C G++ G+ C ++ D C +
Sbjct: 405 TGKTCQLDANECEAKPCVNAKSCKNLIASYYC-DCLPGWM--GQNCDININDCLGQCQND 461
Query: 140 RRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSCRNE 188
C + Y C CP GY G C D+DEC PC + C+NE
Sbjct: 462 ASC--RDLVNGYRCI-CPPGYA--GDHCERDIDEC-ASNPCLNGGHCQNE 505
Score = 60.9 bits (141), Expect = 2e-08
Identities = 83/322 (25%), Positives = 112/322 (34%), Gaps = 45/322 (13%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C D G+RC PG + C++NPC G CQ+ R+QC CP+GF GN
Sbjct: 464 CRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGG-HCQN-EINRFQC-LCPTGFSGN 520
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
+ C N C G C C CP Y +G+ C H+ D PC
Sbjct: 521 LCQLDIDYCEPNPCQNGAQCYNRASDYFC-KCPEDY--EGKNCSHLKDHCRTTPCEVIDS 577
Query: 142 CMPKSTSPYYECEGCPSGYQW-NGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C S P G ++ + C +C C N+
Sbjct: 578 CTVAMAS-----NDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDC-NKGFTGTYCHENIN 631
Query: 201 XXXSQGWRGTGNERRREHCVD-VDE----CADG--RANCPRG-RLCVNTPQYPSNPVSSL 252
S R G C+D V+ C+DG A C C P + L
Sbjct: 632 DCESNPCRNGGT------CIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDL 685
Query: 253 QGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQKCVCNTGWTG 309
+ C C + T C DS +CD + C C G KC+C GW
Sbjct: 686 VNDFYC-DCKNGWKGKT---CHSRDS---QCDEATCNN-GGTCYDEGDAFKCMCPGGW-- 735
Query: 310 NGTVCGLDRDLDGHPDEQLPCN 331
GT C + R+ P+ PC+
Sbjct: 736 EGTTCNIARNSSCLPN---PCH 754
Score = 53.6 bits (123), Expect = 3e-06
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 16/169 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C+D ++C G + + +T CS NPC G C+DL + Y C C +G+
Sbjct: 641 GGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGT-CRDLVNDFY-C-DCKNGW 697
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQ---KPCG 137
G C TC G +C + KC CP G+ +G C ++ PC
Sbjct: 698 KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKC-MCPGGW--EGTTCNIARNSSCLPNPCH 754
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSC 185
C+ S + C C G W G C + ++C PC + +C
Sbjct: 755 NGGTCVVNGES--FTCV-CKEG--WEGPICAQNTNDCS-PHPCYNSGTC 797
Score = 51.6 bits (118), Expect = 1e-05
Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 26/166 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
CVD D +RCE PG D + C ++PC G C D +G Y+C CP G +
Sbjct: 797 CVDGDNWYRCECAPGFAGPDCRININECQSSPCAFG-ATCVDEING-YRC-VCPPGH--S 851
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCM 143
G +C +S R V + ++ C +C + C V +PC +
Sbjct: 852 GAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQC--LNGRIACSKVWCGPRPC-----LL 904
Query: 144 PKSTSPYYECEGCPSGYQWNGYTCVDM--DECDLIRPCDDLVSCRN 187
K S CPS G +C+ + D+C + PC + CR+
Sbjct: 905 HKGHSE------CPS-----GQSCIPILDDQC-FVHPCTGVGECRS 938
Score = 32.3 bits (70), Expect = 7.0
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 10/94 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFG-GRVPCQDLPDGRYQCGKCPSG 79
G CVD G+RC PG G C+ S PC G V +PDG C +
Sbjct: 832 GATCVDEINGYRCVCPPG---HSGAKCQEV-SGRPCITMGSV----IPDGAKWDDDCNTC 883
Query: 80 FHGNG-VECYRISCRANTCFQGVSCEETQYGPKC 112
NG + C ++ C C E G C
Sbjct: 884 QCLNGRIACSKVWCGPRPCLLHKGHSECPSGQSC 917
>BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 68.9 bits (161), Expect = 7e-11
Identities = 54/176 (30%), Positives = 74/176 (42%), Gaps = 16/176 (9%)
Query: 15 PFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCG 74
P CV C + Q CE G Q D + + PC G C + +YQC
Sbjct: 267 PHPGCVHGICNEPWQCL-CETNWGGQLCD-KDLNYCGTHQPCLNGGT-CSNTGPDKYQCS 323
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQK 134
CP G+ G E +C ++ C SC+ET G +C C G+ G C D
Sbjct: 324 -CPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFEC-ECSPGWTGP--TCSTNIDDCS 379
Query: 135 P--CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
P C C ++C CP QW G TC +D +EC+ +PC + SC+N
Sbjct: 380 PNNCSHGGTCQDLVNG--FKCV-CPP--QWTGKTCQLDANECE-AKPCVNAKSCKN 429
Score = 64.9 bits (151), Expect = 1e-09
Identities = 56/170 (32%), Positives = 73/170 (42%), Gaps = 20/170 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C +T GF CE PG G TC T CS N C G CQDL +G ++C CP +
Sbjct: 351 CKETSLGFECECSPGWT---GPTCSTNIDDCSPNNCSHGGT-CQDLVNG-FKC-VCPPQW 404
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQKPCGRE 139
G + C A C SC+ C C G++ G+ C ++ D C +
Sbjct: 405 TGKTCQLDANECEAKPCVNAKSCKNLIASYYC-DCLPGWM--GQNCDININDCLGQCQND 461
Query: 140 RRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSCRNE 188
C + Y C CP GY G C D+DEC PC + C+NE
Sbjct: 462 ASC--RDLVNGYRCI-CPPGYA--GDHCERDIDEC-ASNPCLNGGHCQNE 505
Score = 60.9 bits (141), Expect = 2e-08
Identities = 83/322 (25%), Positives = 112/322 (34%), Gaps = 45/322 (13%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C D G+RC PG + C++NPC G CQ+ R+QC CP+GF GN
Sbjct: 464 CRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGG-HCQN-EINRFQC-LCPTGFSGN 520
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
+ C N C G C C CP Y +G+ C H+ D PC
Sbjct: 521 LCQLDIDYCEPNPCQNGAQCYNRASDYFC-KCPEDY--EGKNCSHLKDHCRTTPCEVIDS 577
Query: 142 CMPKSTSPYYECEGCPSGYQW-NGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C S P G ++ + C +C C N+
Sbjct: 578 CTVAMAS-----NDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDC-NKGFTGTYCHENIN 631
Query: 201 XXXSQGWRGTGNERRREHCVD-VDE----CADG--RANCPRG-RLCVNTPQYPSNPVSSL 252
S R G C+D V+ C+DG A C C P + L
Sbjct: 632 DCESNPCRNGGT------CIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDL 685
Query: 253 QGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQKCVCNTGWTG 309
+ C C + T C DS +CD + C C G KC+C GW
Sbjct: 686 VNDFYC-DCKNGWKGKT---CHSRDS---QCDEATCNN-GGTCYDEGDAFKCMCPGGW-- 735
Query: 310 NGTVCGLDRDLDGHPDEQLPCN 331
GT C + R+ P+ PC+
Sbjct: 736 EGTTCNIARNSSCLPN---PCH 754
Score = 53.6 bits (123), Expect = 3e-06
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 16/169 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C+D ++C G + + +T CS NPC G C+DL + Y C C +G+
Sbjct: 641 GGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGT-CRDLVNDFY-C-DCKNGW 697
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQ---KPCG 137
G C TC G +C + KC CP G+ +G C ++ PC
Sbjct: 698 KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKC-MCPGGW--EGTTCNIARNSSCLPNPCH 754
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSC 185
C+ S + C C G W G C + ++C PC + +C
Sbjct: 755 NGGTCVVNGES--FTCV-CKEG--WEGPICAQNTNDCS-PHPCYNSGTC 797
Score = 51.6 bits (118), Expect = 1e-05
Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 26/166 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
CVD D +RCE PG D + C ++PC G C D +G Y+C CP G +
Sbjct: 797 CVDGDNWYRCECAPGFAGPDCRININECQSSPCAFG-ATCVDEING-YRC-VCPPGH--S 851
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCM 143
G +C +S R V + ++ C +C + C V +PC +
Sbjct: 852 GAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQC--LNGRIACSKVWCGPRPC-----LL 904
Query: 144 PKSTSPYYECEGCPSGYQWNGYTCVDM--DECDLIRPCDDLVSCRN 187
K S CPS G +C+ + D+C + PC + CR+
Sbjct: 905 HKGHSE------CPS-----GQSCIPILDDQC-FVHPCTGVGECRS 938
Score = 32.3 bits (70), Expect = 7.0
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 10/94 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFG-GRVPCQDLPDGRYQCGKCPSG 79
G CVD G+RC PG G C+ S PC G V +PDG C +
Sbjct: 832 GATCVDEINGYRCVCPPG---HSGAKCQEV-SGRPCITMGSV----IPDGAKWDDDCNTC 883
Query: 80 FHGNG-VECYRISCRANTCFQGVSCEETQYGPKC 112
NG + C ++ C C E G C
Sbjct: 884 QCLNGRIACSKVWCGPRPCLLHKGHSECPSGQSC 917
>BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 68.9 bits (161), Expect = 7e-11
Identities = 54/176 (30%), Positives = 74/176 (42%), Gaps = 16/176 (9%)
Query: 15 PFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCG 74
P CV C + Q CE G Q D + + PC G C + +YQC
Sbjct: 267 PHPGCVHGICNEPWQCL-CETNWGGQLCD-KDLNYCGTHQPCLNGGT-CSNTGPDKYQCS 323
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQK 134
CP G+ G E +C ++ C SC+ET G +C C G+ G C D
Sbjct: 324 -CPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFEC-ECSPGWTGP--TCSTNIDDCS 379
Query: 135 P--CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
P C C ++C CP QW G TC +D +EC+ +PC + SC+N
Sbjct: 380 PNNCSHGGTCQDLVNG--FKCV-CPP--QWTGKTCQLDANECE-AKPCVNAKSCKN 429
Score = 64.9 bits (151), Expect = 1e-09
Identities = 56/170 (32%), Positives = 73/170 (42%), Gaps = 20/170 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C +T GF CE PG G TC T CS N C G CQDL +G ++C CP +
Sbjct: 351 CKETSLGFECECSPGWT---GPTCSTNIDDCSPNNCSHGGT-CQDLVNG-FKC-VCPPQW 404
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQKPCGRE 139
G + C A C SC+ C C G++ G+ C ++ D C +
Sbjct: 405 TGKTCQLDANECEAKPCVNAKSCKNLIASYYC-DCLPGWM--GQNCDININDCLGQCQND 461
Query: 140 RRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSCRNE 188
C + Y C CP GY G C D+DEC PC + C+NE
Sbjct: 462 ASC--RDLVNGYRCI-CPPGYA--GDHCERDIDEC-ASNPCLNGGHCQNE 505
Score = 60.9 bits (141), Expect = 2e-08
Identities = 83/322 (25%), Positives = 112/322 (34%), Gaps = 45/322 (13%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C D G+RC PG + C++NPC G CQ+ R+QC CP+GF GN
Sbjct: 464 CRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGG-HCQN-EINRFQC-LCPTGFSGN 520
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
+ C N C G C C CP Y +G+ C H+ D PC
Sbjct: 521 LCQLDIDYCEPNPCQNGAQCYNRASDYFC-KCPEDY--EGKNCSHLKDHCRTTPCEVIDS 577
Query: 142 CMPKSTSPYYECEGCPSGYQW-NGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C S P G ++ + C +C C N+
Sbjct: 578 CTVAMAS-----NDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDC-NKGFTGTYCHENIN 631
Query: 201 XXXSQGWRGTGNERRREHCVD-VDE----CADG--RANCPRG-RLCVNTPQYPSNPVSSL 252
S R G C+D V+ C+DG A C C P + L
Sbjct: 632 DCESNPCRNGGT------CIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDL 685
Query: 253 QGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQKCVCNTGWTG 309
+ C C + T C DS +CD + C C G KC+C GW
Sbjct: 686 VNDFYC-DCKNGWKGKT---CHSRDS---QCDEATCNN-GGTCYDEGDAFKCMCPGGW-- 735
Query: 310 NGTVCGLDRDLDGHPDEQLPCN 331
GT C + R+ P+ PC+
Sbjct: 736 EGTTCNIARNSSCLPN---PCH 754
Score = 53.6 bits (123), Expect = 3e-06
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 16/169 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C+D ++C G + + +T CS NPC G C+DL + Y C C +G+
Sbjct: 641 GGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGT-CRDLVNDFY-C-DCKNGW 697
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQ---KPCG 137
G C TC G +C + KC CP G+ +G C ++ PC
Sbjct: 698 KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKC-MCPGGW--EGTTCNIARNSSCLPNPCH 754
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSC 185
C+ S + C C G W G C + ++C PC + +C
Sbjct: 755 NGGTCVVNGES--FTCV-CKEG--WEGPICAQNTNDCS-PHPCYNSGTC 797
Score = 51.6 bits (118), Expect = 1e-05
Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 26/166 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
CVD D +RCE PG D + C ++PC G C D +G Y+C CP G +
Sbjct: 797 CVDGDNWYRCECAPGFAGPDCRININECQSSPCAFG-ATCVDEING-YRC-VCPPGH--S 851
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCM 143
G +C +S R V + ++ C +C + C V +PC +
Sbjct: 852 GAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQC--LNGRIACSKVWCGPRPC-----LL 904
Query: 144 PKSTSPYYECEGCPSGYQWNGYTCVDM--DECDLIRPCDDLVSCRN 187
K S CPS G +C+ + D+C + PC + CR+
Sbjct: 905 HKGHSE------CPS-----GQSCIPILDDQC-FVHPCTGVGECRS 938
Score = 32.3 bits (70), Expect = 7.0
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 10/94 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFG-GRVPCQDLPDGRYQCGKCPSG 79
G CVD G+RC PG G C+ S PC G V +PDG C +
Sbjct: 832 GATCVDEINGYRCVCPPG---HSGAKCQEV-SGRPCITMGSV----IPDGAKWDDDCNTC 883
Query: 80 FHGNG-VECYRISCRANTCFQGVSCEETQYGPKC 112
NG + C ++ C C E G C
Sbjct: 884 QCLNGRIACSKVWCGPRPCLLHKGHSECPSGQSC 917
>BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 68.9 bits (161), Expect = 7e-11
Identities = 54/176 (30%), Positives = 74/176 (42%), Gaps = 16/176 (9%)
Query: 15 PFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCG 74
P CV C + Q CE G Q D + + PC G C + +YQC
Sbjct: 267 PHPGCVHGICNEPWQCL-CETNWGGQLCD-KDLNYCGTHQPCLNGGT-CSNTGPDKYQCS 323
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQK 134
CP G+ G E +C ++ C SC+ET G +C C G+ G C D
Sbjct: 324 -CPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFEC-ECSPGWTGP--TCSTNIDDCS 379
Query: 135 P--CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
P C C ++C CP QW G TC +D +EC+ +PC + SC+N
Sbjct: 380 PNNCSHGGTCQDLVNG--FKCV-CPP--QWTGKTCQLDANECE-AKPCVNAKSCKN 429
Score = 64.9 bits (151), Expect = 1e-09
Identities = 56/170 (32%), Positives = 73/170 (42%), Gaps = 20/170 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C +T GF CE PG G TC T CS N C G CQDL +G ++C CP +
Sbjct: 351 CKETSLGFECECSPGWT---GPTCSTNIDDCSPNNCSHGGT-CQDLVNG-FKC-VCPPQW 404
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQKPCGRE 139
G + C A C SC+ C C G++ G+ C ++ D C +
Sbjct: 405 TGKTCQLDANECEAKPCVNAKSCKNLIASYYC-DCLPGWM--GQNCDININDCLGQCQND 461
Query: 140 RRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSCRNE 188
C + Y C CP GY G C D+DEC PC + C+NE
Sbjct: 462 ASC--RDLVNGYRCI-CPPGYA--GDHCERDIDEC-ASNPCLNGGHCQNE 505
Score = 60.9 bits (141), Expect = 2e-08
Identities = 83/322 (25%), Positives = 112/322 (34%), Gaps = 45/322 (13%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C D G+RC PG + C++NPC G CQ+ R+QC CP+GF GN
Sbjct: 464 CRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGG-HCQN-EINRFQC-LCPTGFSGN 520
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
+ C N C G C C CP Y +G+ C H+ D PC
Sbjct: 521 LCQLDIDYCEPNPCQNGAQCYNRASDYFC-KCPEDY--EGKNCSHLKDHCRTTPCEVIDS 577
Query: 142 CMPKSTSPYYECEGCPSGYQW-NGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C S P G ++ + C +C C N+
Sbjct: 578 CTVAMAS-----NDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDC-NKGFTGTYCHENIN 631
Query: 201 XXXSQGWRGTGNERRREHCVD-VDE----CADG--RANCPRG-RLCVNTPQYPSNPVSSL 252
S R G C+D V+ C+DG A C C P + L
Sbjct: 632 DCESNPCRNGGT------CIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDL 685
Query: 253 QGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQKCVCNTGWTG 309
+ C C + T C DS +CD + C C G KC+C GW
Sbjct: 686 VNDFYC-DCKNGWKGKT---CHSRDS---QCDEATCNN-GGTCYDEGDAFKCMCPGGW-- 735
Query: 310 NGTVCGLDRDLDGHPDEQLPCN 331
GT C + R+ P+ PC+
Sbjct: 736 EGTTCNIARNSSCLPN---PCH 754
Score = 53.6 bits (123), Expect = 3e-06
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 16/169 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C+D ++C G + + +T CS NPC G C+DL + Y C C +G+
Sbjct: 641 GGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGT-CRDLVNDFY-C-DCKNGW 697
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQ---KPCG 137
G C TC G +C + KC CP G+ +G C ++ PC
Sbjct: 698 KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKC-MCPGGW--EGTTCNIARNSSCLPNPCH 754
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSC 185
C+ S + C C G W G C + ++C PC + +C
Sbjct: 755 NGGTCVVNGES--FTCV-CKEG--WEGPICAQNTNDCS-PHPCYNSGTC 797
Score = 51.6 bits (118), Expect = 1e-05
Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 26/166 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
CVD D +RCE PG D + C ++PC G C D +G Y+C CP G +
Sbjct: 797 CVDGDNWYRCECAPGFAGPDCRININECQSSPCAFG-ATCVDEING-YRC-VCPPGH--S 851
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCM 143
G +C +S R V + ++ C +C + C V +PC +
Sbjct: 852 GAKCQEVSGRPCITMGSVIRDGAKWDDDCNTCQC--LNGRIACSKVWCGPRPC-----LL 904
Query: 144 PKSTSPYYECEGCPSGYQWNGYTCVDM--DECDLIRPCDDLVSCRN 187
K S CPS G +C+ + D+C + PC + CR+
Sbjct: 905 HKGHSE------CPS-----GQSCIPILDDQC-FVHPCTGVGECRS 938
>AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 68.9 bits (161), Expect = 7e-11
Identities = 54/176 (30%), Positives = 74/176 (42%), Gaps = 16/176 (9%)
Query: 15 PFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCG 74
P CV C + Q CE G Q D + + PC G C + +YQC
Sbjct: 267 PHPGCVHGICNEPWQCL-CETNWGGQLCD-KDLNYCGTHQPCLNGGT-CSNTGPDKYQCS 323
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQK 134
CP G+ G E +C ++ C SC+ET G +C C G+ G C D
Sbjct: 324 -CPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFEC-ECSPGWTGP--TCSTNIDDCS 379
Query: 135 P--CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
P C C ++C CP QW G TC +D +EC+ +PC + SC+N
Sbjct: 380 PNNCSHGGTCQDLVNG--FKCV-CPP--QWTGKTCQLDANECE-AKPCVNAKSCKN 429
Score = 64.9 bits (151), Expect = 1e-09
Identities = 56/170 (32%), Positives = 73/170 (42%), Gaps = 20/170 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C +T GF CE PG G TC T CS N C G CQDL +G ++C CP +
Sbjct: 351 CKETSLGFECECSPGWT---GPTCSTNIDDCSPNNCSHGGT-CQDLVNG-FKC-VCPPQW 404
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQKPCGRE 139
G + C A C SC+ C C G++ G+ C ++ D C +
Sbjct: 405 TGKTCQLDANECEAKPCVNAKSCKNLIASYYC-DCLPGWM--GQNCDININDCLGQCQND 461
Query: 140 RRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSCRNE 188
C + Y C CP GY G C D+DEC PC + C+NE
Sbjct: 462 ASC--RDLVNGYRCI-CPPGYA--GDHCERDIDEC-ASNPCLNGGHCQNE 505
Score = 60.9 bits (141), Expect = 2e-08
Identities = 83/322 (25%), Positives = 112/322 (34%), Gaps = 45/322 (13%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C D G+RC PG + C++NPC G CQ+ R+QC CP+GF GN
Sbjct: 464 CRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGG-HCQN-EINRFQC-LCPTGFSGN 520
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
+ C N C G C C CP Y +G+ C H+ D PC
Sbjct: 521 LCQLDIDYCEPNPCQNGAQCYNRASDYFC-KCPEDY--EGKNCSHLKDHCRTTPCEVIDS 577
Query: 142 CMPKSTSPYYECEGCPSGYQW-NGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C S P G ++ + C +C C N+
Sbjct: 578 CTVAMAS-----NDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDC-NKGFTGTYCHENIN 631
Query: 201 XXXSQGWRGTGNERRREHCVD-VDE----CADG--RANCPRG-RLCVNTPQYPSNPVSSL 252
S R G C+D V+ C+DG A C C P + L
Sbjct: 632 DCESNPCRNGGT------CIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDL 685
Query: 253 QGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQKCVCNTGWTG 309
+ C C + T C DS +CD + C C G KC+C GW
Sbjct: 686 VNDFYC-DCKNGWKGKT---CHSRDS---QCDEATCNN-GGTCYDEGDAFKCMCPGGW-- 735
Query: 310 NGTVCGLDRDLDGHPDEQLPCN 331
GT C + R+ P+ PC+
Sbjct: 736 EGTTCNIARNSSCLPN---PCH 754
Score = 53.6 bits (123), Expect = 3e-06
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 16/169 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C+D ++C G + + +T CS NPC G C+DL + Y C C +G+
Sbjct: 641 GGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGT-CRDLVNDFY-C-DCKNGW 697
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQ---KPCG 137
G C TC G +C + KC CP G+ +G C ++ PC
Sbjct: 698 KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKC-MCPGGW--EGTTCNIARNSSCLPNPCH 754
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSC 185
C+ S + C C G W G C + ++C PC + +C
Sbjct: 755 NGGTCVVNGES--FTCV-CKEG--WEGPICAQNTNDCS-PHPCYNSGTC 797
Score = 51.6 bits (118), Expect = 1e-05
Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 26/166 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
CVD D +RCE PG D + C ++PC G C D +G Y+C CP G +
Sbjct: 797 CVDGDNWYRCECAPGFAGPDCRININECQSSPCAFG-ATCVDEING-YRC-VCPPGH--S 851
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCM 143
G +C +S R V + ++ C +C + C V +PC +
Sbjct: 852 GAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQC--LNGRIACSKVWCGPRPC-----LL 904
Query: 144 PKSTSPYYECEGCPSGYQWNGYTCVDM--DECDLIRPCDDLVSCRN 187
K S CPS G +C+ + D+C + PC + CR+
Sbjct: 905 HKGHSE------CPS-----GQSCIPILDDQC-FVHPCTGVGECRS 938
Score = 32.3 bits (70), Expect = 7.0
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 10/94 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFG-GRVPCQDLPDGRYQCGKCPSG 79
G CVD G+RC PG G C+ S PC G V +PDG C +
Sbjct: 832 GATCVDEINGYRCVCPPG---HSGAKCQEV-SGRPCITMGSV----IPDGAKWDDDCNTC 883
Query: 80 FHGNG-VECYRISCRANTCFQGVSCEETQYGPKC 112
NG + C ++ C C E G C
Sbjct: 884 QCLNGRIACSKVWCGPRPCLLHKGHSECPSGQSC 917
>AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein.
Length = 1200
Score = 68.9 bits (161), Expect = 7e-11
Identities = 53/162 (32%), Positives = 72/162 (44%), Gaps = 15/162 (9%)
Query: 15 PFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCG 74
P+ CV CV+ Q CE G D + S +PC G PD +Y+C
Sbjct: 278 PYPGCVHGSCVEPWQ-CNCETNWGGLLCD-KDLNYCGSHHPCTNGGTCINAEPD-QYRC- 333
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--A 132
CP G+ G E +C +N C G SC E G +C CP+G+ G C D A
Sbjct: 334 TCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFEC-HCPSGW--SGPTCALDIDECA 390
Query: 133 QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
PC C+ + +EC CP QW G TC +D+++C
Sbjct: 391 SNPCAAGGTCVDQVDG--FECI-CPE--QWVGATCQLDVNDC 427
Score = 62.5 bits (145), Expect = 6e-09
Identities = 53/157 (33%), Positives = 63/157 (40%), Gaps = 17/157 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCR---TACSANPCFGGRVPCQDLPDGRYQCGKCP 77
G CVD GF C CP G TC+ C GG C+DL +G YQC CP
Sbjct: 397 GGTCVDQVDGFECI-CPEQWV--GATCQLDVNDCRGQCQHGGT--CKDLVNG-YQC-VCP 449
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCG 137
GF G E R C ++ C G CE+ G C CP G+ G + PC
Sbjct: 450 RGFGGRHCELERDKCASSPCHSGGLCEDLADGFHC-HCPQGFSGPLCEVDVDLCEPSPCR 508
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
RC YY C CP + G C V + C
Sbjct: 509 NGARCY-NLEGDYY-C-ACPDDF--GGKNCSVPREPC 540
Score = 56.4 bits (130), Expect = 4e-07
Identities = 48/164 (29%), Positives = 69/164 (42%), Gaps = 18/164 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C+D FRC CP +G+ C T C +PC R C DL + Y C C
Sbjct: 610 GGTCIDEVDAFRCF-CPSGW--EGELCDTNPNDCLPDPCHS-RGRCYDLVNDFY-CA-CD 663
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDG-RQCQHVCDAQKPC 136
G+ G C A TC G +C ++ +C +CP G+ G ++ PC
Sbjct: 664 DGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRC-ACPPGWKGSTCAVAKNSSCLPNPC 722
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPC 179
C+ S + C C G W G TC + ++C+ + PC
Sbjct: 723 VNGGTCVGSGAS--FSCI-CRDG--WEGRTCTHNTNDCNPL-PC 760
Score = 54.4 bits (125), Expect = 2e-06
Identities = 41/142 (28%), Positives = 61/142 (42%), Gaps = 13/142 (9%)
Query: 19 CV-GERCVDTDQGFRCERCPGSQTSDGQTCR---TACSANPCFGGRVPCQDLPDGRYQCG 74
CV G CV + F C G + G+TC C+ PC+ G + C D + ++C
Sbjct: 722 CVNGGTCVGSGASFSCICRDGWE---GRTCTHNTNDCNPLPCYNGGI-CVDGVNW-FRC- 775
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQK 134
+C GF G C+++ C G +C + G +C SCP G G +CQ V +
Sbjct: 776 ECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRC-SCPPGRAGP--RCQEVIGFGR 832
Query: 135 PCGRERRCMPKSTSPYYECEGC 156
C P +S +C C
Sbjct: 833 SCWSRGTPFPHGSSWVEDCNSC 854
Score = 43.2 bits (97), Expect = 0.004
Identities = 36/118 (30%), Positives = 48/118 (40%), Gaps = 9/118 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G CVD FRCE PG D + C ++PC G C D +G Y+C CP G
Sbjct: 763 GGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYG-ATCVDEING-YRC-SCPPG- 818
Query: 81 HGNGVECYRISCRANTCF-QGVSCEE-TQYGPKCGSCPTGYVGDGRQCQHVCDAQKPC 136
G C + +C+ +G + + C SC + R C V KPC
Sbjct: 819 -RAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRC--LDGRRDCSKVWCGWKPC 873
>AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein
Jagged 1 protein.
Length = 1218
Score = 68.9 bits (161), Expect = 7e-11
Identities = 54/176 (30%), Positives = 74/176 (42%), Gaps = 16/176 (9%)
Query: 15 PFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCG 74
P CV C + Q CE G Q D + + PC G C + +YQC
Sbjct: 267 PHPGCVHGICNEPWQCL-CETNWGGQLCD-KDLNYCGTHQPCLNGGT-CSNTGPDKYQCS 323
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQK 134
CP G+ G E +C ++ C SC+ET G +C C G+ G C D
Sbjct: 324 -CPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFEC-ECSPGWTGP--TCSTNIDDCS 379
Query: 135 P--CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
P C C ++C CP QW G TC +D +EC+ +PC + SC+N
Sbjct: 380 PNNCSHGGTCQDLVNG--FKCV-CPP--QWTGKTCQLDANECE-AKPCVNAKSCKN 429
Score = 64.9 bits (151), Expect = 1e-09
Identities = 56/170 (32%), Positives = 73/170 (42%), Gaps = 20/170 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C +T GF CE PG G TC T CS N C G CQDL +G ++C CP +
Sbjct: 351 CKETSLGFECECSPGWT---GPTCSTNIDDCSPNNCSHGGT-CQDLVNG-FKC-VCPPQW 404
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQKPCGRE 139
G + C A C SC+ C C G++ G+ C ++ D C +
Sbjct: 405 TGKTCQLDANECEAKPCVNAKSCKNLIASYYC-DCLPGWM--GQNCDININDCLGQCQND 461
Query: 140 RRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSCRNE 188
C + Y C CP GY G C D+DEC PC + C+NE
Sbjct: 462 ASC--RDLVNGYRCI-CPPGYA--GDHCERDIDEC-ASNPCLNGGHCQNE 505
Score = 60.9 bits (141), Expect = 2e-08
Identities = 83/322 (25%), Positives = 112/322 (34%), Gaps = 45/322 (13%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C D G+RC PG + C++NPC G CQ+ R+QC CP+GF GN
Sbjct: 464 CRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGG-HCQN-EINRFQC-LCPTGFSGN 520
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
+ C N C G C C CP Y +G+ C H+ D PC
Sbjct: 521 LCQLDIDYCEPNPCQNGAQCYNRASDYFC-KCPEDY--EGKNCSHLKDHCRTTPCEVIDS 577
Query: 142 CMPKSTSPYYECEGCPSGYQW-NGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C S P G ++ + C +C C N+
Sbjct: 578 CTVAMAS-----NDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDC-NKGFTGTYCHENIN 631
Query: 201 XXXSQGWRGTGNERRREHCVD-VDE----CADG--RANCPRG-RLCVNTPQYPSNPVSSL 252
S R G C+D V+ C+DG A C C P + L
Sbjct: 632 DCESNPCRNGGT------CIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDL 685
Query: 253 QGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQKCVCNTGWTG 309
+ C C + T C DS +CD + C C G KC+C GW
Sbjct: 686 VNDFYC-DCKNGWKGKT---CHSRDS---QCDEATCNN-GGTCYDEGDAFKCMCPGGW-- 735
Query: 310 NGTVCGLDRDLDGHPDEQLPCN 331
GT C + R+ P+ PC+
Sbjct: 736 EGTTCNIARNSSCLPN---PCH 754
Score = 53.6 bits (123), Expect = 3e-06
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 16/169 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C+D ++C G + + +T CS NPC G C+DL + Y C C +G+
Sbjct: 641 GGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGT-CRDLVNDFY-C-DCKNGW 697
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQ---KPCG 137
G C TC G +C + KC CP G+ +G C ++ PC
Sbjct: 698 KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKC-MCPGGW--EGTTCNIARNSSCLPNPCH 754
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSC 185
C+ S + C C G W G C + ++C PC + +C
Sbjct: 755 NGGTCVVNGES--FTCV-CKEG--WEGPICAQNTNDCS-PHPCYNSGTC 797
Score = 51.6 bits (118), Expect = 1e-05
Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 26/166 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
CVD D +RCE PG D + C ++PC G C D +G Y+C CP G +
Sbjct: 797 CVDGDNWYRCECAPGFAGPDCRININECQSSPCAFG-ATCVDEING-YRC-VCPPGH--S 851
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCM 143
G +C +S R V + ++ C +C + C V +PC +
Sbjct: 852 GAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQC--LNGRIACSKVWCGPRPC-----LL 904
Query: 144 PKSTSPYYECEGCPSGYQWNGYTCVDM--DECDLIRPCDDLVSCRN 187
K S CPS G +C+ + D+C + PC + CR+
Sbjct: 905 HKGHSE------CPS-----GQSCIPILDDQC-FVHPCTGVGECRS 938
Score = 32.3 bits (70), Expect = 7.0
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 10/94 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFG-GRVPCQDLPDGRYQCGKCPSG 79
G CVD G+RC PG G C+ S PC G V +PDG C +
Sbjct: 832 GATCVDEINGYRCVCPPG---HSGAKCQEV-SGRPCITMGSV----IPDGAKWDDDCNTC 883
Query: 80 FHGNG-VECYRISCRANTCFQGVSCEETQYGPKC 112
NG + C ++ C C E G C
Sbjct: 884 QCLNGRIACSKVWCGPRPCLLHKGHSECPSGQSC 917
>AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein.
Length = 1218
Score = 68.9 bits (161), Expect = 7e-11
Identities = 54/176 (30%), Positives = 74/176 (42%), Gaps = 16/176 (9%)
Query: 15 PFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCG 74
P CV C + Q CE G Q D + + PC G C + +YQC
Sbjct: 267 PHPGCVHGICNEPWQCL-CETNWGGQLCD-KDLNYCGTHQPCLNGGT-CSNTGPDKYQCS 323
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQK 134
CP G+ G E +C ++ C SC+ET G +C C G+ G C D
Sbjct: 324 -CPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFEC-ECSPGWTGP--TCSTNIDDCS 379
Query: 135 P--CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
P C C ++C CP QW G TC +D +EC+ +PC + SC+N
Sbjct: 380 PNNCSHGGTCQDLVNG--FKCV-CPP--QWTGKTCQLDANECE-AKPCVNAKSCKN 429
Score = 66.9 bits (156), Expect = 3e-10
Identities = 57/170 (33%), Positives = 73/170 (42%), Gaps = 20/170 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C +T GF CE PG G TC T CS N C G CQDL +G ++C CP +
Sbjct: 351 CKETSLGFECECSPGWT---GPTCSTNIDDCSPNNCSHGGT-CQDLVNG-FKC-VCPPQW 404
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQKPCGRE 139
G + C A C SC+ C C G++ G+ C ++ D C +
Sbjct: 405 TGKTCQLDANECEAKPCVNAKSCKNLIASYYC-DCLPGWM--GQNCDININDCLGQCQND 461
Query: 140 RRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSCRNE 188
C + Y C CP GY G C D+DEC PC D C+NE
Sbjct: 462 ASC--RDLVNGYRCI-CPPGYA--GDHCERDIDEC-ASNPCLDGGHCQNE 505
Score = 60.5 bits (140), Expect = 2e-08
Identities = 83/322 (25%), Positives = 112/322 (34%), Gaps = 45/322 (13%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C D G+RC PG + C++NPC G CQ+ R+QC CP+GF GN
Sbjct: 464 CRDLVNGYRCICPPGYAGDHCERDIDECASNPCLDGG-HCQN-EINRFQC-LCPTGFSGN 520
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
+ C N C G C C CP Y +G+ C H+ D PC
Sbjct: 521 LCQLDIDYCEPNPCQNGAQCYNRASDYFC-KCPEDY--EGKNCSHLKDHCRTTPCEVIDS 577
Query: 142 CMPKSTSPYYECEGCPSGYQW-NGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C S P G ++ + C +C C N+
Sbjct: 578 CTVAMAS-----NDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDC-NKGFTGTYCHENIN 631
Query: 201 XXXSQGWRGTGNERRREHCVD-VDE----CADG--RANCPRG-RLCVNTPQYPSNPVSSL 252
S R G C+D V+ C+DG A C C P + L
Sbjct: 632 DCESNPCRNGGT------CIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDL 685
Query: 253 QGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQKCVCNTGWTG 309
+ C C + T C DS +CD + C C G KC+C GW
Sbjct: 686 VNDFYC-DCKNGWKGKT---CHSRDS---QCDEATCNN-GGTCYDEGDAFKCMCPGGW-- 735
Query: 310 NGTVCGLDRDLDGHPDEQLPCN 331
GT C + R+ P+ PC+
Sbjct: 736 EGTTCNIARNSSCLPN---PCH 754
Score = 53.6 bits (123), Expect = 3e-06
Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 16/169 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C+D ++C G + + +T CS NPC G C+DL + Y C C +G+
Sbjct: 641 GGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGT-CRDLVNDFY-C-DCKNGW 697
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQ---KPCG 137
G C TC G +C + KC CP G+ +G C ++ PC
Sbjct: 698 KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKC-MCPGGW--EGTTCNIARNSSCLPNPCH 754
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSC 185
C+ S + C C G W G C + ++C PC + +C
Sbjct: 755 NGGTCVVNGES--FTCV-CKEG--WEGPICAQNTNDCS-PHPCYNSGTC 797
Score = 51.6 bits (118), Expect = 1e-05
Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 26/166 (15%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
CVD D +RCE PG D + C ++PC G C D +G Y+C CP G +
Sbjct: 797 CVDGDNWYRCECAPGFAGPDCRININECQSSPCAFG-ATCVDEING-YRC-VCPPGH--S 851
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCM 143
G +C +S R V + ++ C +C + C V +PC +
Sbjct: 852 GAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQC--LNGRIACSKVWCGPRPC-----LL 904
Query: 144 PKSTSPYYECEGCPSGYQWNGYTCVDM--DECDLIRPCDDLVSCRN 187
K S CPS G +C+ + D+C + PC + CR+
Sbjct: 905 HKGHSE------CPS-----GQSCIPILDDQC-FVHPCTGVGECRS 938
Score = 32.3 bits (70), Expect = 7.0
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 10/94 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFG-GRVPCQDLPDGRYQCGKCPSG 79
G CVD G+RC PG G C+ S PC G V +PDG C +
Sbjct: 832 GATCVDEINGYRCVCPPG---HSGAKCQEV-SGRPCITMGSV----IPDGAKWDDDCNTC 883
Query: 80 FHGNG-VECYRISCRANTCFQGVSCEETQYGPKC 112
NG + C ++ C C E G C
Sbjct: 884 QCLNGRIACSKVWCGPRPCLLHKGHSECPSGQSC 917
>U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein.
Length = 2911
Score = 68.5 bits (160), Expect = 9e-11
Identities = 69/241 (28%), Positives = 94/241 (39%), Gaps = 29/241 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRT---ACS--ANPCFGGRVPCQDLPDGRYQ 72
+C+ C +T F C G G T T C A+ C C ++P G ++
Sbjct: 1334 ICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNC-DMHASCLNIP-GSFK 1391
Query: 73 CGKCPSGFHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV 129
C C G+ GNG++C + C T C C T +C +C G+ GDG C V
Sbjct: 1392 CS-CREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRC-ACSEGFTGDGFTCSDV 1449
Query: 130 CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLVSCRN 187
+ + + Y CE C G+ + +C D+DEC C +C N
Sbjct: 1450 DECAENINLCENGQCLNVPGAYRCE-CEMGFTPASDSRSCQDIDECSFQNICVS-GTCNN 1507
Query: 188 EEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP-QYPS 246
G GN C D+DECAD NC G LCVNTP +Y
Sbjct: 1508 LPGMFHCICDDGYELDRTG----GN------CTDIDECAD-PINCVNG-LCVNTPGRYEC 1555
Query: 247 N 247
N
Sbjct: 1556 N 1556
Score = 63.7 bits (148), Expect = 2e-09
Identities = 87/336 (25%), Positives = 129/336 (38%), Gaps = 56/336 (16%)
Query: 18 LCVGERCVDTDQGFRCERCP-GSQTSDG-QTC----RTACSANPCFGGRVPCQDLPDGRY 71
LC G CV+T+ F+C+ CP G + S + C + S N C G+ C ++ G Y
Sbjct: 1167 LCRGGTCVNTEGSFQCD-CPLGHELSPSREDCVDINECSLSDNLCRNGK--CVNM-IGTY 1222
Query: 72 QCGKCPSGFHG--NGVECYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQC 126
QC C G+ + C I C C ++ +C SC GY + DGR C
Sbjct: 1223 QC-SCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYEC-SCSEGYALMPDGRSC 1280
Query: 127 QHV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLIRPCDDL 182
+ C+ +C + Y C C G+ + TC+D++ECDL
Sbjct: 1281 ADIDECENNPDICDGGQC--TNIPGEYRCL-CYDGFMASMDMKTCIDVNECDLNSNICMF 1337
Query: 183 VSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
C N + G ++ C DVDEC G NC C+N P
Sbjct: 1338 GECENTKGSFICHCQL----------GYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIP 1387
Query: 243 QYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQ 299
GS+ C C + N + C D D + ++ NA C
Sbjct: 1388 -----------GSFKC-SCREGWIGNGIK-CIDLDEC---SNGTHQCSINAQCVNTPGSY 1431
Query: 300 KCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRC 335
+C C+ G+TG+G C D+D + C +C
Sbjct: 1432 RCACSEGFTGDGFTCS---DVDECAENINLCENGQC 1464
Score = 63.7 bits (148), Expect = 2e-09
Identities = 84/307 (27%), Positives = 114/307 (37%), Gaps = 51/307 (16%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQ-TSDGQTCRTACSANPCFGG-RVPCQDLPDGRYQCGK 75
LC +CV+ ++C PG Q T D Q C GG C + +G Y+C
Sbjct: 1209 LCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTN-SEGSYECS- 1266
Query: 76 CPSGFH--GNGVECYRIS-CRANTCF-QGVSCEETQYGPKCGSCPTGYVG--DGRQCQHV 129
C G+ +G C I C N G C +C C G++ D + C V
Sbjct: 1267 CSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRC-LCYDGFMASMDMKTCIDV 1325
Query: 130 --CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYT--CVDMDECDL-IRPCDDLVS 184
CD C ++T + C C GY T C D+DEC++ CD S
Sbjct: 1326 NECDLNSNICMFGEC--ENTKGSFICH-CQLGYSVKKGTTGCTDVDECEIGAHNCDMHAS 1382
Query: 185 CRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQY 244
C N +GW G G + C+D+DEC++G C CVNTP
Sbjct: 1383 CLN-------IPGSFKCSCREGWIGNGIK-----CIDLDECSNGTHQCSINAQCVNTP-- 1428
Query: 245 PSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSL---VKRCDPSYCRRFNAVCGFGQKC 301
GSY C G + C D D + C+ C V G +C
Sbjct: 1429 ---------GSYRCACSEG--FTGDGFTCSDVDECAENINLCENGQCLN---VPG-AYRC 1473
Query: 302 VCNTGWT 308
C G+T
Sbjct: 1474 ECEMGFT 1480
Score = 57.6 bits (133), Expect = 2e-07
Identities = 89/321 (27%), Positives = 117/321 (36%), Gaps = 54/321 (16%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTS--DGQTCR--TACSANP--CFGGRVPCQDLPDGRY 71
LC CV+T F CE G ++ + C C NP C GG C + +G +
Sbjct: 1124 LCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGG--TCVN-TEGSF 1180
Query: 72 QCGKCPSGF-----HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGR 124
QC CP G + V+ S N C G C +C SC GY D +
Sbjct: 1181 QC-DCPLGHELSPSREDCVDINECSLSDNLCRNG-KCVNMIGTYQC-SCNPGYQATPDRQ 1237
Query: 125 QCQHVCDAQ-KPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDD 181
C + + G + +C S YEC C GY +G +C D+DEC+ D
Sbjct: 1238 GCTDIDECMIMNGGCDTQCTNSEGS--YEC-SCSEGYALMPDGRSCADIDECENNPDICD 1294
Query: 182 LVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNT 241
C N + G + C+DV+EC C G C NT
Sbjct: 1295 GGQCTN----------IPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGE-CENT 1343
Query: 242 PQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSL---VKRCDPSYCRRFNAVCGFG 298
+GS+IC G+ T C D D CD + N F
Sbjct: 1344 -----------KGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCD-MHASCLNIPGSF- 1390
Query: 299 QKCVCNTGWTGNGTVCGLDRD 319
KC C GW GNG C +D D
Sbjct: 1391 -KCSCREGWIGNGIKC-IDLD 1409
Score = 57.6 bits (133), Expect = 2e-07
Identities = 53/182 (29%), Positives = 76/182 (41%), Gaps = 22/182 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTAC-SANPCFGGRVPCQDL---PDGRYQC 73
LC +C++T FRC C T+D T+C + C PC + +G YQC
Sbjct: 2458 LCTNGQCINTMGSFRCF-CKVGYTTD--ISGTSCIDLDECSQSPKPCNYICKNTEGSYQC 2514
Query: 74 GKCPSGF--HGNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQC--QH 128
CP G+ +G C + C+ C T G C CP G+ C +
Sbjct: 2515 S-CPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTC-KCPPGFTQHHTACIDNN 2572
Query: 129 VCDAQKP-CGRERRCMPKSTSPYYECEGCPSGYQWN--GYTCVDMDECDLIRPCDDLVSC 185
C +Q CG + C ++T + CE C G+ + G C D+DECD C C
Sbjct: 2573 ECGSQPLLCGGKGIC--QNTPGSFSCE-CQRGFSLDATGLNCEDVDECDGNHRCQH--GC 2627
Query: 186 RN 187
+N
Sbjct: 2628 QN 2629
Score = 53.6 bits (123), Expect = 3e-06
Identities = 51/169 (30%), Positives = 73/169 (43%), Gaps = 23/169 (13%)
Query: 18 LCVGERCVDTDQGFRCERCPG-SQTSDGQTCRT-ACSANPCFGGRVPCQDLPDGRYQCGK 75
LC+ RC+ T +RCE G Q ++G C++NPC G C + P G Y C K
Sbjct: 503 LCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTNG--DCVNTP-GSYYC-K 558
Query: 76 CPSGFHGNGVECYRISCRANTCFQ-GVSCEETQYGPKCGS----CPTGY--VGDGRQC-- 126
C +GF + + + C Q GV C+ + GS C G+ DG+ C
Sbjct: 559 CHAGFQRTPTK--QACIDIDECIQNGVLCKNGRCVNSDGSFQCICNAGFELTTDGKNCVD 616
Query: 127 QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDEC 173
C C C+ + S ++C C G+ NG C D+DEC
Sbjct: 617 HDECTTTNMC-LNGMCINEDGS--FKCI-CKPGFVLAPNGRYCTDVDEC 661
Score = 53.6 bits (123), Expect = 3e-06
Identities = 85/330 (25%), Positives = 126/330 (38%), Gaps = 50/330 (15%)
Query: 1 MHAGSMGDAGSMVTPFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGR 60
+H G D +C C++ FRCE CP + S + C G
Sbjct: 1800 IHTGKAVDIDECKEIPGICANGVCINQIGSFRCE-CP-TGFSYNDLLLVCEDIDECSNGD 1857
Query: 61 VPCQDLPD-----GRYQCGKCPSGF--HGNGVECYRISCR--ANTCFQGVSCEETQYGPK 111
CQ D G Y+C +C +GF NG R C N C G+ C + Q +
Sbjct: 1858 NLCQRNADCINSPGSYRC-ECAAGFKLSPNGACVDRNECLEIPNVCSHGL-CVDLQGSYQ 1915
Query: 112 CGSCPTGYVG--DGRQCQHVCDAQK-PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV 168
C C G+ D C V + ++ PCG C K+T Y C P + C+
Sbjct: 1916 C-ICHNGFKASQDQTMCMDVDECERHPCG-NGTC--KNTVGSYNCLCYPGFELTHNNDCL 1971
Query: 169 DMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADG 228
D+DEC CRN ++G+ T + + +C+D +EC
Sbjct: 1972 DIDECSSFFG----QVCRN--GRCFNEIGSFKCLCNEGYELTPDGK---NCIDTNECVAL 2022
Query: 229 RANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYC 288
+C G C N L+GS+ C+ C Y V + C D + + DP+ C
Sbjct: 2023 PGSCSPG-TCQN-----------LEGSFRCI-CPPGYEVKSEN-CIDINECDE--DPNIC 2066
Query: 289 RRFNAVCGF--GQKCVCNTGW--TGNGTVC 314
F + G +C+C G+ + NG C
Sbjct: 2067 -LFGSCTNTPGGFQCLCPPGFVLSDNGRRC 2095
Score = 53.2 bits (122), Expect = 4e-06
Identities = 85/335 (25%), Positives = 129/335 (38%), Gaps = 61/335 (18%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQ--TSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQC 73
LC G C++T F+CE CP + D + C C A+P G C + G Y C
Sbjct: 1659 LCQGGNCINTFGSFQCE-CPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTL-GNYTC 1716
Query: 74 GKCPSGFH--GNGVECYRISCRANTCFQ---GVSCE-ETQYG-PKCGSCPTGYVGDGRQC 126
CP + G C + R + C++ G +CE E + K C T VG
Sbjct: 1717 -ICPPEYMQVNGGHNC--MDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKA--- 1770
Query: 127 QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYT--CVDMDECDLIRPCDDLVS 184
KPC C T+ + G G+ ++ +T VD+DEC I
Sbjct: 1771 -----GNKPC---EPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGV 1822
Query: 185 CRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQY 244
C N+ + G C D+DEC++G C R C+N+P
Sbjct: 1823 CINQ----------IGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSP-- 1870
Query: 245 PSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVC 303
GSY C C + ++ C D + ++ P+ C V G +C+C
Sbjct: 1871 ---------GSYRC-ECAAGFKLSPNGACVDRNECLE--IPNVCSHGLCVDLQGSYQCIC 1918
Query: 304 NTGW--TGNGTVCGLDRDLDGHPDEQLPCNEPRCK 336
+ G+ + + T+C +D E+ PC CK
Sbjct: 1919 HNGFKASQDQTMC-----MDVDECERHPCGNGTCK 1948
Score = 52.8 bits (121), Expect = 5e-06
Identities = 81/316 (25%), Positives = 113/316 (35%), Gaps = 52/316 (16%)
Query: 21 GERCVDTDQGF-----RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGK 75
G RC DT Q F +C + + + CS P G PC+ P +
Sbjct: 2092 GRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQ 2151
Query: 76 --CPSGFHGNGVECYRISCRANTCFQ--GV----SCEETQYGPKCGSCPTGYVGD--GRQ 125
CP G HG + N C + G+ C T +C CP GY D G +
Sbjct: 2152 DLCPYG-HGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRC-ECPMGYNLDYTGVR 2209
Query: 126 CQHV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGY-TCVDMDECDLIRPCDDL 182
C C PCG C S +EC C G++ C D++EC P
Sbjct: 2210 CVDTDECSIGNPCGNGT-CTNVIGS--FECN-CNEGFEPGPMMNCEDINECAQ-NPLLCA 2264
Query: 183 VSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC-PRGRLCVNT 241
+ C N G ++ C D+DECA+G +C RG +C N
Sbjct: 2265 LRCMNTFGSYECTCPI----------GYALREDQKMCKDLDECAEGLHDCESRGMMCKN- 2313
Query: 242 PQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-K 300
L G+++C+ G C D + R P C V G +
Sbjct: 2314 ----------LIGTFMCICPPGMARRPDGEGCVDENEC--RTKPGICENGRCVNIIGSYR 2361
Query: 301 CVCNTGW--TGNGTVC 314
C CN G+ + +GT C
Sbjct: 2362 CECNEGFQSSSSGTEC 2377
Score = 50.0 bits (114), Expect = 3e-05
Identities = 86/334 (25%), Positives = 118/334 (35%), Gaps = 65/334 (19%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQ-TSDGQTC--RTACSA-NPCFGGRVPCQD-------- 65
LC RCV++D F+C G + T+DG+ C C+ N C G +D
Sbjct: 584 LCKNGRCVNSDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICK 643
Query: 66 -----LPDGRY-----QC---GKCPSGFHGNGVECYRISCRANTC--FQGVSCEETQYGP 110
P+GRY +C G C +G N +R C G C +T
Sbjct: 644 PGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRS 703
Query: 111 KC------GSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEG-CPSGYQWN 163
C G C + G + + C A G C P E G C SG
Sbjct: 704 TCYGGIKKGVCVRPFPGAVTKSECCC-ANPDYGFGEPCQPCPAKNSAEFHGLCSSGV--- 759
Query: 164 GYTCV--DMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVD 221
G T D++EC L D C N + G+ + R +C+D
Sbjct: 760 GITVDGRDINECAL-----DPDICAN--GICENLRGSYRCNCNSGYEPDASGR---NCID 809
Query: 222 VDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVK 281
+DEC R C G LC NTP GSY C G+ + T C D +
Sbjct: 810 IDECLVNRLLCDNG-LCRNTP-----------GSYSCTCPPGYVFRTETETCEDINECES 857
Query: 282 R-CDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
C CR N + F +C + + G +C
Sbjct: 858 NPCVNGACR--NNLGSFNCECSPGSKLSSTGLIC 889
Score = 48.4 bits (110), Expect = 1e-04
Identities = 65/233 (27%), Positives = 88/233 (37%), Gaps = 39/233 (16%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGG--RVPCQDLPDGRYQCGK 75
+C RCV+ +RCE G Q+S T CF + CQ R K
Sbjct: 2347 ICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTK 2406
Query: 76 ---CPSGFHGNGVECYRISCRANTC-FQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
C G G G +C C G + QY C P GY DGR C
Sbjct: 2407 SECCCDGGRGWGHQC-------ELCPLPGTA----QYKKICPHGP-GYTTDGRDIDE-CK 2453
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLI-RPCDDLVSCRNE 188
+C+ +T + C C GY +G +C+D+DEC +PC+ + C+N
Sbjct: 2454 VMPNLCTNGQCI--NTMGSFRC-FCKVGYTTDISGTSCIDLDECSQSPKPCNYI--CKNT 2508
Query: 189 EXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNT 241
E RG + + C D+DEC + NC LCVNT
Sbjct: 2509 EGSYQCSCP----------RGYVLQEDGKTCKDLDECQTKQHNCQ--FLCVNT 2549
Score = 48.0 bits (109), Expect = 1e-04
Identities = 50/188 (26%), Positives = 75/188 (39%), Gaps = 25/188 (13%)
Query: 8 DAGSMVTPFKLCVGERCVDTDQGFRCERCPGSQTS-DGQTCRTACSANPCFGG---RVPC 63
D TP +C+ C++++ FRC+ PG DG+ C + C+GG V
Sbjct: 657 DVDECQTP-GICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCV 715
Query: 64 QDLPDG--RYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG 121
+ P + +C C + +G G C + + F G+ C S G
Sbjct: 716 RPFPGAVTKSECC-CANPDYGFGEPCQPCPAKNSAEFHGL----------CSS-GVGITV 763
Query: 122 DGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPC 179
DGR C C ++ Y C C SGY+ +G C+D+DEC + R
Sbjct: 764 DGRDINE-CALDPDICANGIC--ENLRGSYRCN-CNSGYEPDASGRNCIDIDECLVNRLL 819
Query: 180 DDLVSCRN 187
D CRN
Sbjct: 820 CDNGLCRN 827
Score = 46.4 bits (105), Expect = 4e-04
Identities = 63/239 (26%), Positives = 85/239 (35%), Gaps = 38/239 (15%)
Query: 21 GERCVDTDQGFRCER-----CPGSQTSDGQTCRTACSANPCFGGRVPCQDLP-DGRYQCG 74
G C+D QG C + +S ++ C + G C+ P G Q
Sbjct: 2374 GTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYK 2433
Query: 75 K-CPSG--FHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGD--GRQC--- 126
K CP G + +G + N C G C T +C C GY D G C
Sbjct: 2434 KICPHGPGYTTDGRDIDECKVMPNLCTNG-QCINTMGSFRC-FCKVGYTTDISGTSCIDL 2491
Query: 127 QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLIRP-CDDLV 183
+ KPC + K+T Y+C CP GY Q +G TC D+DEC + C L
Sbjct: 2492 DECSQSPKPCNY----ICKNTEGSYQCS-CPRGYVLQEDGKTCKDLDECQTKQHNCQFL- 2545
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
C N G + C+D +EC C +C NTP
Sbjct: 2546 -CVNTLGGFTCKCP------------PGFTQHHTACIDNNECGSQPLLCGGKGICQNTP 2591
Score = 46.0 bits (104), Expect = 5e-04
Identities = 50/179 (27%), Positives = 70/179 (39%), Gaps = 36/179 (20%)
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGY-TCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXX 199
RC+P +S Y CE C GY+ + C+D+DEC PC + C N
Sbjct: 508 RCIPTVSS--YRCE-CNMGYKQDANGDCIDVDECTS-NPCTN-GDCVNTPGSYYCKCHA- 561
Query: 200 XXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICV 259
G++ T ++ C+D+DEC C GR CVN+ GS+ C+
Sbjct: 562 ------GFQRTPT---KQACIDIDECIQNGVLCKNGR-CVNS-----------DGSFQCI 600
Query: 260 PCGGHYYVNTTRPCFDPD--SLVKRCDPSYCRRFNAVCGFGQKCVCNTGW--TGNGTVC 314
G + C D D + C C N F KC+C G+ NG C
Sbjct: 601 CNAGFELTTDGKNCVDHDECTTTNMCLNGMC--INEDGSF--KCICKPGFVLAPNGRYC 655
Score = 44.0 bits (99), Expect = 0.002
Identities = 52/179 (29%), Positives = 75/179 (41%), Gaps = 23/179 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSD-GQTC----RTACSANPCFGG-RVP-CQDLPDGR 70
+C+ C +T GF+C PG SD G+ C ++ C N G VP + +
Sbjct: 2065 ICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAK 2124
Query: 71 YQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVC 130
C K P G G C FQ + C YG G+ P+ + D R+ + C
Sbjct: 2125 CCCSKMPG--EGWGDPCELCPKDDEVAFQDL-CP---YGH--GTVPS--LHDTREDVNEC 2174
Query: 131 DAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLVSCRN 187
+C+ +T + CE CP GY + G CVD DEC + PC + +C N
Sbjct: 2175 LESPGICSNGQCI--NTDGSFRCE-CPMGYNLDYTGVRCVDTDECSIGNPCGN-GTCTN 2229
Score = 41.5 bits (93), Expect = 0.011
Identities = 34/104 (32%), Positives = 45/104 (43%), Gaps = 20/104 (19%)
Query: 219 CVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDS 278
C+DVDEC C G CVNTP GSY C G T + C D D
Sbjct: 532 CIDVDECTSN--PCTNGD-CVNTP-----------GSYYCKCHAGFQRTPTKQACIDIDE 577
Query: 279 LVKRCDPSYCRRFNAVCGFGQ-KCVCNTGW--TGNGTVCGLDRD 319
++ + C+ V G +C+CN G+ T +G C +D D
Sbjct: 578 CIQ--NGVLCKNGRCVNSDGSFQCICNAGFELTTDGKNC-VDHD 618
Score = 36.7 bits (81), Expect = 0.33
Identities = 53/199 (26%), Positives = 77/199 (38%), Gaps = 34/199 (17%)
Query: 53 ANPCFGGRVPCQDLPD-GRYQCGKCPSGFH--GNGVECYRIS-CRANTCFQGVSCEETQY 108
AN C GR C +P Y+C +C G+ NG +C + C +N C G C T
Sbjct: 501 ANLCLNGR--C--IPTVSSYRC-ECNMGYKQDANG-DCIDVDECTSNPCTNG-DCVNTPG 553
Query: 109 GPKCGSCPTGY--VGDGRQCQHV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW-- 162
C C G+ + C + C + RC+ S ++C C +G++
Sbjct: 554 SYYC-KCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNSDGS--FQCI-CNAGFELTT 609
Query: 163 NGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDV 222
+G CVD DEC C + + C NE+ G +C DV
Sbjct: 610 DGKNCVDHDECTTTNMCLNGM-CINEDGSFKCICKPGFVLAPNG----------RYCTDV 658
Query: 223 DECADGRANCPRGRLCVNT 241
DEC C G C+N+
Sbjct: 659 DEC-QTPGICMNGH-CINS 675
Score = 36.3 bits (80), Expect = 0.43
Identities = 32/109 (29%), Positives = 49/109 (44%), Gaps = 8/109 (7%)
Query: 84 GVECYRISCRANTCFQ-GVSCEETQYGPKCGSCPTGYVGDGRQ--CQHVCDAQKPCGRER 140
G+ C + C A T G CE P+ C G++ + R CQ V + Q G +
Sbjct: 230 GIVCTKTLCCATTGRAWGHPCEMCPAQPQ--PCRRGFIPNIRTGACQDVDECQAIPGICQ 287
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYT--CVDMDECDLIRPCDDLVSCRN 187
+T +EC CP+G++ + T C D+DEC +I + C N
Sbjct: 288 GGNCINTVGSFECR-CPAGHKQSETTQKCEDIDECSIIPGICETGECSN 335
Score = 35.9 bits (79), Expect = 0.57
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 11/90 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPG--SQTSDGQTCR--TACSANPCFGGRVPCQDLPDGRYQC 73
+C G C++T F C RCP Q+ Q C CS P C + G Y C
Sbjct: 285 ICQGGNCINTVGSFEC-RCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTV-GSYFC 342
Query: 74 GKCPSGF--HGNGVECYRISCRANTCFQGV 101
CP G+ +G C I R CF G+
Sbjct: 343 -VCPRGYVTSTDGSRC--IDQRTGMCFSGL 369
Score = 33.9 bits (74), Expect = 2.3
Identities = 34/120 (28%), Positives = 50/120 (41%), Gaps = 14/120 (11%)
Query: 8 DAGSMVTPFKLCVGERCVDTDQGFRCERCPG-SQTSDGQTCR--TACS-ANPCFGGRVPC 63
D LC +C++ +RCE G + SD ++C+ CS N C G C
Sbjct: 1448 DVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVSG--TC 1505
Query: 64 QDLPDGRYQCGKCPSGFH--GNGVECYRISCRAN--TCFQGVSCEETQYGPKCGSCPTGY 119
+LP G + C C G+ G C I A+ C G+ C T +C +CP +
Sbjct: 1506 NNLP-GMFHC-ICDDGYELDRTGGNCTDIDECADPINCVNGL-CVNTPGRYEC-NCPPDF 1561
>AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital
contractural arachnodactyly) variant protein.
Length = 1976
Score = 68.5 bits (160), Expect = 9e-11
Identities = 69/241 (28%), Positives = 94/241 (39%), Gaps = 29/241 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRT---ACS--ANPCFGGRVPCQDLPDGRYQ 72
+C+ C +T F C G G T T C A+ C C ++P G ++
Sbjct: 399 ICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNC-DMHASCLNIP-GSFK 456
Query: 73 CGKCPSGFHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV 129
C C G+ GNG++C + C T C C T +C +C G+ GDG C V
Sbjct: 457 CS-CREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRC-ACSEGFTGDGFTCSDV 514
Query: 130 CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLVSCRN 187
+ + + Y CE C G+ + +C D+DEC C +C N
Sbjct: 515 DECAENINLCENGQCLNVPGAYRCE-CEMGFTPASDSRSCQDIDECSFQNICV-FGTCNN 572
Query: 188 EEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP-QYPS 246
G GN C D+DECAD NC G LCVNTP +Y
Sbjct: 573 LPGMFHCICDDGYELDRTG----GN------CTDIDECAD-PINCVNG-LCVNTPGRYEC 620
Query: 247 N 247
N
Sbjct: 621 N 621
Score = 63.7 bits (148), Expect = 2e-09
Identities = 87/336 (25%), Positives = 129/336 (38%), Gaps = 56/336 (16%)
Query: 18 LCVGERCVDTDQGFRCERCP-GSQTSDG-QTC----RTACSANPCFGGRVPCQDLPDGRY 71
LC G CV+T+ F+C+ CP G + S + C + S N C G+ C ++ G Y
Sbjct: 232 LCRGGTCVNTEGSFQCD-CPLGHELSPSREDCVDINECSLSDNLCRNGK--CVNM-IGTY 287
Query: 72 QCGKCPSGFHG--NGVECYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQC 126
QC C G+ + C I C C ++ +C SC GY + DGR C
Sbjct: 288 QC-SCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYEC-SCSEGYALMPDGRSC 345
Query: 127 QHV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLIRPCDDL 182
+ C+ +C + Y C C G+ + TC+D++ECDL
Sbjct: 346 ADIDECENNPDICDGGQC--TNIPGEYRCL-CYDGFMASMDMKTCIDVNECDLNSNICMF 402
Query: 183 VSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
C N + G ++ C DVDEC G NC C+N P
Sbjct: 403 GECENTKGSFICHCQL----------GYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIP 452
Query: 243 QYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQ 299
GS+ C C + N + C D D + ++ NA C
Sbjct: 453 -----------GSFKC-SCREGWIGNGIK-CIDLDEC---SNGTHQCSINAQCVNTPGSY 496
Query: 300 KCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRC 335
+C C+ G+TG+G C D+D + C +C
Sbjct: 497 RCACSEGFTGDGFTCS---DVDECAENINLCENGQC 529
Score = 63.7 bits (148), Expect = 2e-09
Identities = 84/307 (27%), Positives = 114/307 (37%), Gaps = 51/307 (16%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQ-TSDGQTCRTACSANPCFGG-RVPCQDLPDGRYQCGK 75
LC +CV+ ++C PG Q T D Q C GG C + +G Y+C
Sbjct: 274 LCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTN-SEGSYECS- 331
Query: 76 CPSGFH--GNGVECYRIS-CRANTCF-QGVSCEETQYGPKCGSCPTGYVG--DGRQCQHV 129
C G+ +G C I C N G C +C C G++ D + C V
Sbjct: 332 CSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRC-LCYDGFMASMDMKTCIDV 390
Query: 130 --CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYT--CVDMDECDL-IRPCDDLVS 184
CD C ++T + C C GY T C D+DEC++ CD S
Sbjct: 391 NECDLNSNICMFGEC--ENTKGSFICH-CQLGYSVKKGTTGCTDVDECEIGAHNCDMHAS 447
Query: 185 CRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQY 244
C N +GW G G + C+D+DEC++G C CVNTP
Sbjct: 448 CLN-------IPGSFKCSCREGWIGNGIK-----CIDLDECSNGTHQCSINAQCVNTP-- 493
Query: 245 PSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSL---VKRCDPSYCRRFNAVCGFGQKC 301
GSY C G + C D D + C+ C V G +C
Sbjct: 494 ---------GSYRCACSEG--FTGDGFTCSDVDECAENINLCENGQCLN---VPG-AYRC 538
Query: 302 VCNTGWT 308
C G+T
Sbjct: 539 ECEMGFT 545
Score = 58.8 bits (136), Expect = 7e-08
Identities = 53/182 (29%), Positives = 76/182 (41%), Gaps = 22/182 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTAC-SANPCFGGRVPCQDL---PDGRYQC 73
LC +C++T FRC C T+D T+C + C PC + +G YQC
Sbjct: 1523 LCTNGQCINTMGSFRCF-CKVGYTTD--ISGTSCIDLDECSQSPKPCNYICKNTEGSYQC 1579
Query: 74 GKCPSGF--HGNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQC--QH 128
CP G+ +G C + C+ C T G C CP G+ C +
Sbjct: 1580 S-CPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTC-KCPPGFTQHHTACIDNN 1637
Query: 129 VCDAQKP-CGRERRCMPKSTSPYYECEGCPSGYQWN--GYTCVDMDECDLIRPCDDLVSC 185
C +Q CG + C ++T + CE C G+ + G C D+DECD C C
Sbjct: 1638 ECGSQPSLCGAKGIC--QNTPGSFSCE-CQRGFSLDATGLNCEDVDECDGNHRCQH--GC 1692
Query: 186 RN 187
+N
Sbjct: 1693 QN 1694
Score = 57.2 bits (132), Expect = 2e-07
Identities = 89/321 (27%), Positives = 117/321 (36%), Gaps = 54/321 (16%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTS--DGQTCR--TACSANP--CFGGRVPCQDLPDGRY 71
LC CV+T F CE G ++ + C C NP C GG C + +G +
Sbjct: 189 LCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGG--TCVN-TEGSF 245
Query: 72 QCGKCPSGF-----HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGR 124
QC CP G + V+ S N C G C +C SC GY D +
Sbjct: 246 QC-DCPLGHELSPSREDCVDINECSLSDNLCRNG-KCVNMIGTYQC-SCNPGYQATPDRQ 302
Query: 125 QCQHVCDAQ-KPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDD 181
C + + G + +C S YEC C GY +G +C D+DEC+ D
Sbjct: 303 GCTDIDECMIMNGGCDTQCTNSEGS--YEC-SCSEGYALMPDGRSCADIDECENNPDICD 359
Query: 182 LVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNT 241
C N + G + C+DV+EC C G C NT
Sbjct: 360 GGQCTN----------IPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGE-CENT 408
Query: 242 PQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSL---VKRCDPSYCRRFNAVCGFG 298
+GS+IC G+ T C D D CD + N F
Sbjct: 409 -----------KGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCD-MHASCLNIPGSF- 455
Query: 299 QKCVCNTGWTGNGTVCGLDRD 319
KC C GW GNG C +D D
Sbjct: 456 -KCSCREGWIGNGIKC-IDLD 474
Score = 53.6 bits (123), Expect = 3e-06
Identities = 85/330 (25%), Positives = 126/330 (38%), Gaps = 50/330 (15%)
Query: 1 MHAGSMGDAGSMVTPFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGR 60
+H G D +C C++ FRCE CP + S + C G
Sbjct: 865 IHTGKAVDIDECKEIPGICANGVCINQIGSFRCE-CP-TGFSYNDLLLVCEDIDECSNGD 922
Query: 61 VPCQDLPD-----GRYQCGKCPSGF--HGNGVECYRISCR--ANTCFQGVSCEETQYGPK 111
CQ D G Y+C +C +GF NG R C N C G+ C + Q +
Sbjct: 923 NLCQRNADCINSPGSYRC-ECAAGFKLSPNGACVDRNECLEIPNVCSHGL-CVDLQGSYQ 980
Query: 112 CGSCPTGYVG--DGRQCQHVCDAQK-PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV 168
C C G+ D C V + ++ PCG C K+T Y C P + C+
Sbjct: 981 C-ICHNGFKASQDQTMCMDVDECERHPCG-NGTC--KNTVGSYNCLCYPGFELTHNNDCL 1036
Query: 169 DMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADG 228
D+DEC CRN ++G+ T + + +C+D +EC
Sbjct: 1037 DIDECSSFFG----QVCRN--GRCFNEIGSFKCLCNEGYELTPDGK---NCIDTNECVAL 1087
Query: 229 RANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYC 288
+C G C N L+GS+ C+ C Y V + C D + + DP+ C
Sbjct: 1088 PGSCSPG-TCQN-----------LEGSFRCI-CPPGYEVKSEN-CIDINECDE--DPNIC 1131
Query: 289 RRFNAVCGF--GQKCVCNTGW--TGNGTVC 314
F + G +C+C G+ + NG C
Sbjct: 1132 -LFGSCTNTPGGFQCLCPPGFVLSDNGRRC 1160
Score = 52.0 bits (119), Expect = 8e-06
Identities = 85/335 (25%), Positives = 129/335 (38%), Gaps = 61/335 (18%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQ--TSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQC 73
LC G C++T F+CE CP + D + C C A+P G C + G Y C
Sbjct: 724 LCQGGNCINTFGSFQCE-CPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTL-GNYTC 781
Query: 74 GKCPSGFH--GNGVECYRISCRANTCFQ---GVSCE-ETQYG-PKCGSCPTGYVGDGRQC 126
CP + G C + R + C++ G +CE E + K C T VG
Sbjct: 782 -ICPPEYMQVNGGHNC--MDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWN- 837
Query: 127 QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYT--CVDMDECDLIRPCDDLVS 184
KPC C T+ + G G+ ++ +T VD+DEC I
Sbjct: 838 -------KPC---EPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGV 887
Query: 185 CRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQY 244
C N+ + G C D+DEC++G C R C+N+P
Sbjct: 888 CINQ----------IGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSP-- 935
Query: 245 PSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVC 303
GSY C C + ++ C D + ++ P+ C V G +C+C
Sbjct: 936 ---------GSYRC-ECAAGFKLSPNGACVDRNECLE--IPNVCSHGLCVDLQGSYQCIC 983
Query: 304 NTGW--TGNGTVCGLDRDLDGHPDEQLPCNEPRCK 336
+ G+ + + T+C +D E+ PC CK
Sbjct: 984 HNGFKASQDQTMC-----MDVDECERHPCGNGTCK 1013
Score = 52.0 bits (119), Expect = 8e-06
Identities = 81/316 (25%), Positives = 112/316 (35%), Gaps = 52/316 (16%)
Query: 21 GERCVDTDQGF-----RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGK 75
G RC DT Q F +C + + + CS P G PC+ P +
Sbjct: 1157 GRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQ 1216
Query: 76 --CPSGFHGNGVECYRISCRANTCFQ--GV----SCEETQYGPKCGSCPTGYVGD--GRQ 125
CP G HG + N C + G+ C T +C CP GY D G +
Sbjct: 1217 DLCPYG-HGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRC-ECPMGYNLDYTGVR 1274
Query: 126 CQHV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGY-TCVDMDECDLIRPCDDL 182
C C PCG C S +EC C G++ C D++EC P
Sbjct: 1275 CVDTDECSIGNPCGNGT-CTNVIGS--FECN-CNEGFEPGPMMNCEDINECAQ-NPLLCA 1329
Query: 183 VSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC-PRGRLCVNT 241
C N G ++ C D+DECA+G +C RG +C N
Sbjct: 1330 FRCMNTFGSYECTCPI----------GYALREDQKMCKDLDECAEGLHDCESRGMMCKN- 1378
Query: 242 PQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-K 300
L G+++C+ G C D + R P C V G +
Sbjct: 1379 ----------LIGTFMCICPPGMARRPDGEGCVDENEC--RTKPGICENGRCVNIIGSYR 1426
Query: 301 CVCNTGW--TGNGTVC 314
C CN G+ + +GT C
Sbjct: 1427 CECNEGFQSSSSGTEC 1442
Score = 48.4 bits (110), Expect = 1e-04
Identities = 65/233 (27%), Positives = 88/233 (37%), Gaps = 39/233 (16%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGG--RVPCQDLPDGRYQCGK 75
+C RCV+ +RCE G Q+S T CF + CQ R K
Sbjct: 1412 ICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTK 1471
Query: 76 ---CPSGFHGNGVECYRISCRANTC-FQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
C G G G +C C G + QY C P GY DGR C
Sbjct: 1472 SECCCDGGRGWGHQC-------ELCPLPGTA----QYKKICPHGP-GYTTDGRDIDE-CK 1518
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLI-RPCDDLVSCRNE 188
+C+ +T + C C GY +G +C+D+DEC +PC+ + C+N
Sbjct: 1519 VMPNLCTNGQCI--NTMGSFRC-FCKVGYTTDISGTSCIDLDECSQSPKPCNYI--CKNT 1573
Query: 189 EXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNT 241
E RG + + C D+DEC + NC LCVNT
Sbjct: 1574 EGSYQCSCP----------RGYVLQEDGKTCKDLDECQTKQHNCQ--FLCVNT 1614
Score = 47.6 bits (108), Expect = 2e-04
Identities = 63/239 (26%), Positives = 86/239 (35%), Gaps = 38/239 (15%)
Query: 21 GERCVDTDQGFRCER-----CPGSQTSDGQTCRTACSANPCFGGRVPCQDLP-DGRYQCG 74
G C+D QG C + +S ++ C + G C+ P G Q
Sbjct: 1439 GTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYK 1498
Query: 75 K-CPSG--FHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGD--GRQC--- 126
K CP G + +G + N C G C T +C C GY D G C
Sbjct: 1499 KICPHGPGYTTDGRDIDECKVMPNLCTNG-QCINTMGSFRC-FCKVGYTTDISGTSCIDL 1556
Query: 127 QHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLIRP-CDDLV 183
+ KPC + K+T Y+C CP GY Q +G TC D+DEC + C L
Sbjct: 1557 DECSQSPKPCNY----ICKNTEGSYQCS-CPRGYVLQEDGKTCKDLDECQTKQHNCQFL- 1610
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
C N G + C+D +EC + C +C NTP
Sbjct: 1611 -CVNTLGGFTCKCP------------PGFTQHHTACIDNNECGSQPSLCGAKGICQNTP 1656
Score = 44.0 bits (99), Expect = 0.002
Identities = 52/179 (29%), Positives = 75/179 (41%), Gaps = 23/179 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSD-GQTC----RTACSANPCFGG-RVP-CQDLPDGR 70
+C+ C +T GF+C PG SD G+ C ++ C N G VP + +
Sbjct: 1130 ICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAK 1189
Query: 71 YQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVC 130
C K P G G C FQ + C YG G+ P+ + D R+ + C
Sbjct: 1190 CCCSKMPG--EGWGDPCELCPKDDEVAFQDL-CP---YGH--GTVPS--LHDTREDVNEC 1239
Query: 131 DAQKPCGRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLVSCRN 187
+C+ +T + CE CP GY + G CVD DEC + PC + +C N
Sbjct: 1240 LESPGICSNGQCI--NTDGSFRCE-CPMGYNLDYTGVRCVDTDECSIGNPCGN-GTCTN 1294
Score = 32.7 bits (71), Expect = 5.3
Identities = 34/120 (28%), Positives = 50/120 (41%), Gaps = 14/120 (11%)
Query: 8 DAGSMVTPFKLCVGERCVDTDQGFRCERCPG-SQTSDGQTCR--TACS-ANPCFGGRVPC 63
D LC +C++ +RCE G + SD ++C+ CS N C G C
Sbjct: 513 DVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFG--TC 570
Query: 64 QDLPDGRYQCGKCPSGFH--GNGVECYRISCRAN--TCFQGVSCEETQYGPKCGSCPTGY 119
+LP G + C C G+ G C I A+ C G+ C T +C +CP +
Sbjct: 571 NNLP-GMFHC-ICDDGYELDRTGGNCTDIDECADPINCVNGL-CVNTPGRYEC-NCPPDF 626
>BC106950-1|AAI06951.1| 685|Homo sapiens delta-like 4 (Drosophila)
protein.
Length = 685
Score = 67.3 bits (157), Expect = 2e-10
Identities = 42/137 (30%), Positives = 58/137 (42%), Gaps = 9/137 (6%)
Query: 21 GERCVDTDQ-GFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C ++ Q + C PG D + + C +NPC G C+D DG Y C CP G
Sbjct: 297 GATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGG-SCKDQEDG-YHC-LCPPG 353
Query: 80 FHGNGVECYRISCRANTCFQGVSCEETQYGPKCG-SCPTGYVGDGRQCQHVCD--AQKPC 136
++G E +SC + CF G SC E G CP + G C+ D PC
Sbjct: 354 YYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGS--NCEKKVDRCTSNPC 411
Query: 137 GRERRCMPKSTSPYYEC 153
+C+ + S C
Sbjct: 412 ANGGQCLNRGPSRMCRC 428
Score = 62.5 bits (145), Expect = 6e-09
Identities = 43/147 (29%), Positives = 64/147 (43%), Gaps = 15/147 (10%)
Query: 21 GERCVDTDQG--FRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
G C + +QG + CE P S+ + C++NPC G Q L G + +C
Sbjct: 374 GGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGG---QCLNRGPSRMCRCRP 430
Query: 79 GFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-----HVCDAQ 133
GF G E + C N C G +C + + G C +CP G+ GR+C+ C A
Sbjct: 431 GFTGTYCELHVSDCARNPCAHGGTCHDLENGLMC-TCPAGF--SGRRCEVRTSIDAC-AS 486
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGY 160
PC C ++ + C CP G+
Sbjct: 487 SPCFNRATCYTDLSTDTFVC-NCPYGF 512
Score = 58.4 bits (135), Expect = 9e-08
Identities = 42/137 (30%), Positives = 56/137 (40%), Gaps = 12/137 (8%)
Query: 54 NPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCG 113
+PC G C + Y C C G+ G E C +N C G SC++ + G C
Sbjct: 292 SPCKNGAT-CSNSGQRSYTC-TCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHC- 348
Query: 114 SCPTGYVGDGRQCQH--VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDM 170
CP GY G C+H + A PC C ++ Y CE CP + G C +
Sbjct: 349 LCPPGYY--GLHCEHSTLSCADSPCFNGGSCRERNQGANYACE-CPPNF--TGSNCEKKV 403
Query: 171 DECDLIRPCDDLVSCRN 187
D C PC + C N
Sbjct: 404 DRC-TSNPCANGGQCLN 419
>AY358894-1|AAQ89253.1| 685|Homo sapiens DLL4 protein.
Length = 685
Score = 67.3 bits (157), Expect = 2e-10
Identities = 42/137 (30%), Positives = 58/137 (42%), Gaps = 9/137 (6%)
Query: 21 GERCVDTDQ-GFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C ++ Q + C PG D + + C +NPC G C+D DG Y C CP G
Sbjct: 297 GATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGG-SCKDQEDG-YHC-LCPPG 353
Query: 80 FHGNGVECYRISCRANTCFQGVSCEETQYGPKCG-SCPTGYVGDGRQCQHVCD--AQKPC 136
++G E +SC + CF G SC E G CP + G C+ D PC
Sbjct: 354 YYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGS--NCEKKVDRCTSNPC 411
Query: 137 GRERRCMPKSTSPYYEC 153
+C+ + S C
Sbjct: 412 ANGGQCLNRGPSRMCRC 428
Score = 62.5 bits (145), Expect = 6e-09
Identities = 43/147 (29%), Positives = 64/147 (43%), Gaps = 15/147 (10%)
Query: 21 GERCVDTDQG--FRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
G C + +QG + CE P S+ + C++NPC G Q L G + +C
Sbjct: 374 GGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGG---QCLNRGPSRMCRCRP 430
Query: 79 GFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-----HVCDAQ 133
GF G E + C N C G +C + + G C +CP G+ GR+C+ C A
Sbjct: 431 GFTGTYCELHVSDCARNPCAHGGTCHDLENGLMC-TCPAGF--SGRRCEVRTSIDAC-AS 486
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGY 160
PC C ++ + C CP G+
Sbjct: 487 SPCFNRATCYTDLSTDTFVC-NCPYGF 512
Score = 58.4 bits (135), Expect = 9e-08
Identities = 42/137 (30%), Positives = 56/137 (40%), Gaps = 12/137 (8%)
Query: 54 NPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCG 113
+PC G C + Y C C G+ G E C +N C G SC++ + G C
Sbjct: 292 SPCKNGAT-CSNSGQRSYTC-TCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHC- 348
Query: 114 SCPTGYVGDGRQCQH--VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDM 170
CP GY G C+H + A PC C ++ Y CE CP + G C +
Sbjct: 349 LCPPGYY--GLHCEHSTLSCADSPCFNGGSCRERNQGANYACE-CPPNF--TGSNCEKKV 403
Query: 171 DECDLIRPCDDLVSCRN 187
D C PC + C N
Sbjct: 404 DRC-TSNPCANGGQCLN 419
>AF279305-1|AAF81912.1| 653|Homo sapiens delta 4 protein.
Length = 653
Score = 67.3 bits (157), Expect = 2e-10
Identities = 42/137 (30%), Positives = 58/137 (42%), Gaps = 9/137 (6%)
Query: 21 GERCVDTDQ-GFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C ++ Q + C PG D + + C +NPC G C+D DG Y C CP G
Sbjct: 265 GATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGG-SCKDQEDG-YHC-LCPPG 321
Query: 80 FHGNGVECYRISCRANTCFQGVSCEETQYGPKCG-SCPTGYVGDGRQCQHVCD--AQKPC 136
++G E +SC + CF G SC E G CP + G C+ D PC
Sbjct: 322 YYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGS--NCEKKVDRCTSNPC 379
Query: 137 GRERRCMPKSTSPYYEC 153
+C+ + S C
Sbjct: 380 ANGGQCLNRGPSRMCRC 396
Score = 62.5 bits (145), Expect = 6e-09
Identities = 43/147 (29%), Positives = 64/147 (43%), Gaps = 15/147 (10%)
Query: 21 GERCVDTDQG--FRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
G C + +QG + CE P S+ + C++NPC G Q L G + +C
Sbjct: 342 GGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGG---QCLNRGPSRMCRCRP 398
Query: 79 GFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-----HVCDAQ 133
GF G E + C N C G +C + + G C +CP G+ GR+C+ C A
Sbjct: 399 GFTGTYCELHVSDCARNPCAHGGTCHDLENGLMC-TCPAGF--SGRRCEVRTSIDAC-AS 454
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGY 160
PC C ++ + C CP G+
Sbjct: 455 SPCFNRATCYTDLSTDTFVC-NCPYGF 480
Score = 58.4 bits (135), Expect = 9e-08
Identities = 42/137 (30%), Positives = 56/137 (40%), Gaps = 12/137 (8%)
Query: 54 NPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCG 113
+PC G C + Y C C G+ G E C +N C G SC++ + G C
Sbjct: 260 SPCKNGAT-CSNSGQRSYTC-TCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHC- 316
Query: 114 SCPTGYVGDGRQCQH--VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDM 170
CP GY G C+H + A PC C ++ Y CE CP + G C +
Sbjct: 317 LCPPGYY--GLHCEHSTLSCADSPCFNGGSCRERNQGANYACE-CPPNF--TGSNCEKKV 371
Query: 171 DECDLIRPCDDLVSCRN 187
D C PC + C N
Sbjct: 372 DRC-TSNPCANGGQCLN 387
>AF253468-1|AAF76427.1| 685|Homo sapiens notch ligand DLL4 protein.
Length = 685
Score = 67.3 bits (157), Expect = 2e-10
Identities = 42/137 (30%), Positives = 58/137 (42%), Gaps = 9/137 (6%)
Query: 21 GERCVDTDQ-GFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C ++ Q + C PG D + + C +NPC G C+D DG Y C CP G
Sbjct: 297 GATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGG-SCKDQEDG-YHC-LCPPG 353
Query: 80 FHGNGVECYRISCRANTCFQGVSCEETQYGPKCG-SCPTGYVGDGRQCQHVCD--AQKPC 136
++G E +SC + CF G SC E G CP + G C+ D PC
Sbjct: 354 YYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGS--NCEKKVDRCTSNPC 411
Query: 137 GRERRCMPKSTSPYYEC 153
+C+ + S C
Sbjct: 412 ANGGQCLNRGPSRMCRC 428
Score = 62.5 bits (145), Expect = 6e-09
Identities = 43/147 (29%), Positives = 64/147 (43%), Gaps = 15/147 (10%)
Query: 21 GERCVDTDQG--FRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
G C + +QG + CE P S+ + C++NPC G Q L G + +C
Sbjct: 374 GGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGG---QCLNRGPSRMCRCRP 430
Query: 79 GFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-----HVCDAQ 133
GF G E + C N C G +C + + G C +CP G+ GR+C+ C A
Sbjct: 431 GFTGTYCELHVSDCARNPCAHGGTCHDLENGLMC-TCPAGF--SGRRCEVRTSIDAC-AS 486
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGY 160
PC C ++ + C CP G+
Sbjct: 487 SPCFNRATCYTDLSTDTFVC-NCPYGF 512
Score = 58.4 bits (135), Expect = 9e-08
Identities = 42/137 (30%), Positives = 56/137 (40%), Gaps = 12/137 (8%)
Query: 54 NPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCG 113
+PC G C + Y C C G+ G E C +N C G SC++ + G C
Sbjct: 292 SPCKNGAT-CSNSGQRSYTC-TCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHC- 348
Query: 114 SCPTGYVGDGRQCQH--VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDM 170
CP GY G C+H + A PC C ++ Y CE CP + G C +
Sbjct: 349 LCPPGYY--GLHCEHSTLSCADSPCFNGGSCRERNQGANYACE-CPPNF--TGSNCEKKV 403
Query: 171 DECDLIRPCDDLVSCRN 187
D C PC + C N
Sbjct: 404 DRC-TSNPCANGGQCLN 419
>AB043894-1|BAB18581.1| 685|Homo sapiens Delta-4 protein.
Length = 685
Score = 67.3 bits (157), Expect = 2e-10
Identities = 42/137 (30%), Positives = 58/137 (42%), Gaps = 9/137 (6%)
Query: 21 GERCVDTDQ-GFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C ++ Q + C PG D + + C +NPC G C+D DG Y C CP G
Sbjct: 297 GATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGG-SCKDQEDG-YHC-LCPPG 353
Query: 80 FHGNGVECYRISCRANTCFQGVSCEETQYGPKCG-SCPTGYVGDGRQCQHVCD--AQKPC 136
++G E +SC + CF G SC E G CP + G C+ D PC
Sbjct: 354 YYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGS--NCEKKVDRCTSNPC 411
Query: 137 GRERRCMPKSTSPYYEC 153
+C+ + S C
Sbjct: 412 ANGGQCLNRGPSRMCRC 428
Score = 62.5 bits (145), Expect = 6e-09
Identities = 43/147 (29%), Positives = 64/147 (43%), Gaps = 15/147 (10%)
Query: 21 GERCVDTDQG--FRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
G C + +QG + CE P S+ + C++NPC G Q L G + +C
Sbjct: 374 GGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGG---QCLNRGPSRMCRCRP 430
Query: 79 GFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-----HVCDAQ 133
GF G E + C N C G +C + + G C +CP G+ GR+C+ C A
Sbjct: 431 GFTGTYCELHVSDCARNPCAHGGTCHDLENGLMC-TCPAGF--SGRRCEVRTSIDAC-AS 486
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGY 160
PC C ++ + C CP G+
Sbjct: 487 SPCFNRATCYTDLSTDTFVC-NCPYGF 512
Score = 58.4 bits (135), Expect = 9e-08
Identities = 42/137 (30%), Positives = 56/137 (40%), Gaps = 12/137 (8%)
Query: 54 NPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCG 113
+PC G C + Y C C G+ G E C +N C G SC++ + G C
Sbjct: 292 SPCKNGAT-CSNSGQRSYTC-TCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHC- 348
Query: 114 SCPTGYVGDGRQCQH--VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDM 170
CP GY G C+H + A PC C ++ Y CE CP + G C +
Sbjct: 349 LCPPGYY--GLHCEHSTLSCADSPCFNGGSCRERNQGANYACE-CPPNF--TGSNCEKKV 403
Query: 171 DECDLIRPCDDLVSCRN 187
D C PC + C N
Sbjct: 404 DRC-TSNPCANGGQCLN 419
>AB036931-1|BAB16085.1| 685|Homo sapiens notch ligand delta-2
protein.
Length = 685
Score = 67.3 bits (157), Expect = 2e-10
Identities = 42/137 (30%), Positives = 58/137 (42%), Gaps = 9/137 (6%)
Query: 21 GERCVDTDQ-GFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C ++ Q + C PG D + + C +NPC G C+D DG Y C CP G
Sbjct: 297 GATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGG-SCKDQEDG-YHC-LCPPG 353
Query: 80 FHGNGVECYRISCRANTCFQGVSCEETQYGPKCG-SCPTGYVGDGRQCQHVCD--AQKPC 136
++G E +SC + CF G SC E G CP + G C+ D PC
Sbjct: 354 YYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGS--NCEKKVDRCTSNPC 411
Query: 137 GRERRCMPKSTSPYYEC 153
+C+ + S C
Sbjct: 412 ANGGQCLNRGPSRMCRC 428
Score = 62.5 bits (145), Expect = 6e-09
Identities = 43/147 (29%), Positives = 64/147 (43%), Gaps = 15/147 (10%)
Query: 21 GERCVDTDQG--FRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPS 78
G C + +QG + CE P S+ + C++NPC G Q L G + +C
Sbjct: 374 GGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGG---QCLNRGPSRMCRCRP 430
Query: 79 GFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-----HVCDAQ 133
GF G E + C N C G +C + + G C +CP G+ GR+C+ C A
Sbjct: 431 GFTGTYCELHVSDCARNPCAHGGTCHDLENGLMC-TCPAGF--SGRRCEVRTSIDAC-AS 486
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGY 160
PC C ++ + C CP G+
Sbjct: 487 SPCFNRATCYTDLSTDTFVC-NCPYGF 512
Score = 58.4 bits (135), Expect = 9e-08
Identities = 42/137 (30%), Positives = 56/137 (40%), Gaps = 12/137 (8%)
Query: 54 NPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCG 113
+PC G C + Y C C G+ G E C +N C G SC++ + G C
Sbjct: 292 SPCKNGAT-CSNSGQRSYTC-TCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHC- 348
Query: 114 SCPTGYVGDGRQCQH--VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDM 170
CP GY G C+H + A PC C ++ Y CE CP + G C +
Sbjct: 349 LCPPGYY--GLHCEHSTLSCADSPCFNGGSCRERNQGANYACE-CPPNF--TGSNCEKKV 403
Query: 171 DECDLIRPCDDLVSCRN 187
D C PC + C N
Sbjct: 404 DRC-TSNPCANGGQCLN 419
>BC008761-1|AAH08761.2| 743|Homo sapiens LTBP3 protein protein.
Length = 743
Score = 66.5 bits (155), Expect = 4e-10
Identities = 86/302 (28%), Positives = 113/302 (37%), Gaps = 51/302 (16%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCF-----GGRVPCQDLPDGRYQCGKCPS 78
C++T + C G + G R+ N C G C + P G Y+C C
Sbjct: 119 CMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFP-GHYKCN-CYP 176
Query: 79 GFHGNGVE---CYRIS-CR-ANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQ 133
G+ C I CR ++C G CE KC +C GY G C
Sbjct: 177 GYRLKASRPPVCEDIDECRDPSSCPDG-KCENKPGSFKCIACQPGYRSQGGGA---CRDV 232
Query: 134 KPCGRERRCMP---KSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSCRNE 188
C C P ++ + C C GY +G +C+D+DEC+ CD+ + C N
Sbjct: 233 NECAEGSPCSPGWCENLPGSFRCT-CAQGYAPAPDGRSCLDVDECEAGDVCDNGI-CSN- 289
Query: 189 EXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNP 248
Q G R R HC D+DEC D A C G C+NT
Sbjct: 290 ---------TPGSFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIGGD-CINT------- 331
Query: 249 VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGF--GQKCVCNTG 306
GSY C+ GH V R C D D + DPS C A CVC+ G
Sbjct: 332 ----NGSYRCLCPQGHRLVG-GRKCQDIDECSQ--DPSLCLPHGACKNLQGSYVCVCDEG 384
Query: 307 WT 308
+T
Sbjct: 385 FT 386
Score = 33.1 bits (72), Expect = 4.0
Identities = 23/67 (34%), Positives = 34/67 (50%), Gaps = 9/67 (13%)
Query: 19 CVGERCVDTDQGFRCERCP-GSQTSDGQTCR--TACSANP--CFGGRVPCQDLPDGRYQC 73
C+G C++T+ +RC CP G + G+ C+ CS +P C C++L G Y C
Sbjct: 323 CIGGDCINTNGSYRC-LCPQGHRLVGGRKCQDIDECSQDPSLCL-PHGACKNL-QGSYVC 379
Query: 74 GKCPSGF 80
C GF
Sbjct: 380 -VCDEGF 385
Score = 33.1 bits (72), Expect = 4.0
Identities = 16/38 (42%), Positives = 24/38 (63%), Gaps = 5/38 (13%)
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDEC 173
+E +C+ +T P YEC C G+ ++G CVD+DEC
Sbjct: 493 KEGKCV--NTQPGYECY-CKQGFYYDGNLLECVDVDEC 527
>AK160380-1|BAD18723.1| 1055|Homo sapiens FLJ00344 protein protein.
Length = 1055
Score = 66.5 bits (155), Expect = 4e-10
Identities = 44/158 (27%), Positives = 62/158 (39%), Gaps = 13/158 (8%)
Query: 20 VGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
+G+ D D G+R C + T D C C + C DG C KC +G
Sbjct: 844 LGDGSCDCDVGWRGVHCDNATTEDN--CNGTCHTS------ANCLTNSDGTASC-KCAAG 894
Query: 80 FHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA-QKP 135
F GNG C I+ C + C C+ T G + +C GY GDG C + +
Sbjct: 895 FQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENH 954
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC 173
CG ++ T P C Y +G C ++ C
Sbjct: 955 CGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVC 992
Score = 55.2 bits (127), Expect = 9e-07
Identities = 38/121 (31%), Positives = 51/121 (42%), Gaps = 8/121 (6%)
Query: 13 VTPFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSAN-PCFGG---RVPCQDLPD 68
+TP C++T G C T +G+ C + P GG C +
Sbjct: 307 LTPGGCSRNAECINTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGP 366
Query: 69 GRYQCGKCPSGFHGNGVECYRI-SCRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQ 125
G+ +C +C GF GNG++C I SC T C SC+ T G C GY GDG
Sbjct: 367 GQNEC-ECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGDGFL 425
Query: 126 C 126
C
Sbjct: 426 C 426
Score = 51.2 bits (117), Expect = 1e-05
Identities = 48/185 (25%), Positives = 70/185 (37%), Gaps = 20/185 (10%)
Query: 18 LCVGERC---VDTDQGFRCERCPGSQTSDGQTC---RTACSANPCFGGRVPCQDLPDGRY 71
LCV C +D+D C S G+ C +AC F + +G
Sbjct: 226 LCVHGTCNNRIDSDGACLTGTCRDG--SAGRLCDKQTSACGPYVQFCHIHATCEYSNGTA 283
Query: 72 QCGKCPSGFHGNGVECYRIS-CRANT---CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ 127
C C +G+ G+G C + C T C + C T G C G+ G+GR C
Sbjct: 284 SC-ICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECINTGTGTHTCVCQQGWTGNGRDCS 342
Query: 128 HVCDAQKP----CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDL 182
+ + P C C+ ECE C G++ NG C + C + C L
Sbjct: 343 EINNCLLPSAGGCHDNASCLYVGPG-QNECE-CKKGFRGNGIDCEPITSCLEQTGKCHPL 400
Query: 183 VSCRN 187
SC++
Sbjct: 401 ASCQS 405
Score = 50.4 bits (115), Expect = 2e-05
Identities = 56/229 (24%), Positives = 83/229 (36%), Gaps = 31/229 (13%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHG 82
+CV T C C G Q C + N CFG + C D +G C +C GF G
Sbjct: 759 KCVRTVITREC--CAGFFGPQCQPC-PGNAQNVCFGNGI-CLDGVNGTGVC-ECGEGFSG 813
Query: 83 NGVE-C----YRISC-RANTCFQGVSCEETQYGPKCGSCPTGYVG---DGRQCQHVCDAQ 133
E C Y I C +A +C G C + G C G+ G D + C+
Sbjct: 814 TACETCTEGKYGIHCDQACSCVHG-RCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGT 872
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIR-PCDDLVSCRNEEXXX 192
C C+ S C+ C +G+Q NG C ++ C++ C C+
Sbjct: 873 --CHTSANCLTNSDGTA-SCK-CAAGFQGNGTICTAINACEISNGGCSAKADCKR----- 923
Query: 193 XXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNT 241
G+ G G C++++ C + C + C T
Sbjct: 924 -TTPGRRVCTCKAGYTGDGIV-----CLEINPCLENHCGCDKNAECTQT 966
Score = 33.1 bits (72), Expect = 4.0
Identities = 68/295 (23%), Positives = 102/295 (34%), Gaps = 45/295 (15%)
Query: 35 RCPGSQTSDGQTCRTACSANPCFGG-RVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCR 93
RCP + C + FG + C + + KC GF+G +C +
Sbjct: 120 RCPANSEPTALFTHR-CVYSGRFGSLKSGCARYCNATVKIPKCCKGFYGP--DCNQCPGG 176
Query: 94 -ANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQK---PCGRERRCMPKSTSP 149
+N C C ++ G C G+ G QCQ D K C ++ C+ + +
Sbjct: 177 FSNPCSGNGQCADSLGGNGTCICEEGF--QGSQCQFCSDPNKYGPRCNKKCLCVHGTCNN 234
Query: 150 YYECEG-CPSGYQWNGYTCVDMDE---CDL-IRPCDDLVSCRNEEXXXXXXXXXXXXXXS 204
+ +G C +G TC D CD C V +
Sbjct: 235 RIDSDGACLTG------TCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICK 288
Query: 205 QGWRGTGNERRREHCVDVDECAD-GRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGG 263
G+ G G C ++D C C R C+NT G++ CV G
Sbjct: 289 AGYEGDGTL-----CSEMDPCTGLTPGGCSRNAECINTGT----------GTHTCVCQQG 333
Query: 264 HYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQ-KCVCNTGWTGNGTVC 314
+ R C + ++ + C NA C G GQ +C C G+ GNG C
Sbjct: 334 --WTGNGRDCSEINNCLLP-SAGGCHD-NASCLYVGPGQNECECKKGFRGNGIDC 384
>AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein.
Length = 1382
Score = 66.5 bits (155), Expect = 4e-10
Identities = 86/302 (28%), Positives = 113/302 (37%), Gaps = 51/302 (16%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCF-----GGRVPCQDLPDGRYQCGKCPS 78
C++T + C G + G R+ N C G C + P G Y+C C
Sbjct: 711 CMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFP-GHYKCN-CYP 768
Query: 79 GFHGNGVE---CYRIS-CR-ANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQ 133
G+ C I CR ++C G CE KC +C GY G C
Sbjct: 769 GYRLKASRPPVCEDIDECRDPSSCPDG-KCENKPGSFKCIACQPGYRSQGGGA---CRDV 824
Query: 134 KPCGRERRCMP---KSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSCRNE 188
C C P ++ + C C GY +G +C+D+DEC+ CD+ + C N
Sbjct: 825 NECAEGSPCSPGWCENLPGSFRCT-CAQGYAPAPDGRSCLDVDECEAGDVCDNGI-CSN- 881
Query: 189 EXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNP 248
Q G R R HC D+DEC D A C G C+NT
Sbjct: 882 ---------TPGSFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIGGD-CINT------- 923
Query: 249 VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGF--GQKCVCNTG 306
GSY C+ GH V R C D D + DPS C A CVC+ G
Sbjct: 924 ----NGSYRCLCPQGHRLVG-GRKCQDIDECSQ--DPSLCLPHGACKNLQGSYVCVCDEG 976
Query: 307 WT 308
+T
Sbjct: 977 FT 978
Score = 45.2 bits (102), Expect = 0.001
Identities = 39/120 (32%), Positives = 48/120 (40%), Gaps = 18/120 (15%)
Query: 219 CVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDS 278
CVDVDEC D +NC G +C NT +G Y C Y R C P+
Sbjct: 1113 CVDVDECLD-ESNCRNG-VCENT-----------RGGYRCACTPPAEYSPAQRQCLSPEE 1159
Query: 279 L-VKRC-DPSYCRRFNAVCGFGQ-KCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRC 335
+ V C DP+ CR V G +C C W + G D L P E+ P C
Sbjct: 1160 MDVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPS--GRDCQLPESPAERAPERRDVC 1217
Score = 40.3 bits (90), Expect = 0.026
Identities = 34/107 (31%), Positives = 46/107 (42%), Gaps = 13/107 (12%)
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLIRPCDDLVSCRNEEXXXXXX 195
+E +C+ +T P YEC C G+ ++G CVD+DE C D +CRN
Sbjct: 1085 KEGKCV--NTQPGYECY-CKQGFYYDGNLLECVDVDE------CLDESNCRNGVCENTRG 1135
Query: 196 XXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
+ + +DVDEC D A C GR CVN P
Sbjct: 1136 GYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAA-CRPGR-CVNLP 1180
Score = 33.1 bits (72), Expect = 4.0
Identities = 23/67 (34%), Positives = 34/67 (50%), Gaps = 9/67 (13%)
Query: 19 CVGERCVDTDQGFRCERCP-GSQTSDGQTCR--TACSANP--CFGGRVPCQDLPDGRYQC 73
C+G C++T+ +RC CP G + G+ C+ CS +P C C++L G Y C
Sbjct: 915 CIGGDCINTNGSYRC-LCPQGHRLVGGRKCQDIDECSQDPSLCL-PHGACKNL-QGSYVC 971
Query: 74 GKCPSGF 80
C GF
Sbjct: 972 -VCDEGF 977
>AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming growth
factor beta binding protein 3 protein.
Length = 1256
Score = 66.5 bits (155), Expect = 4e-10
Identities = 86/302 (28%), Positives = 113/302 (37%), Gaps = 51/302 (16%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCF-----GGRVPCQDLPDGRYQCGKCPS 78
C++T + C G + G R+ N C G C + P G Y+C C
Sbjct: 632 CMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFP-GHYKCN-CYP 689
Query: 79 GFHGNGVE---CYRIS-CR-ANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQ 133
G+ C I CR ++C G CE KC +C GY G C
Sbjct: 690 GYRLKASRPPVCEDIDECRDPSSCPDG-KCENKPGSFKCIACQPGYRSQGGGA---CRDV 745
Query: 134 KPCGRERRCMP---KSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSCRNE 188
C C P ++ + C C GY +G +C+D+DEC+ CD+ + C N
Sbjct: 746 NECAEGSPCSPGWCENLPGSFRCT-CAQGYAPAPDGRSCLDVDECEAGDVCDNGI-CSN- 802
Query: 189 EXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNP 248
Q G R R HC D+DEC D A C G C+NT
Sbjct: 803 ---------TPGSFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIGGD-CINT------- 844
Query: 249 VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGF--GQKCVCNTG 306
GSY C+ GH V R C D D + DPS C A CVC+ G
Sbjct: 845 ----NGSYRCLCPQGHRLVG-GRKCQDIDECSQ--DPSLCLPHGACKNLQGSYVCVCDEG 897
Query: 307 WT 308
+T
Sbjct: 898 FT 899
Score = 33.1 bits (72), Expect = 4.0
Identities = 23/67 (34%), Positives = 34/67 (50%), Gaps = 9/67 (13%)
Query: 19 CVGERCVDTDQGFRCERCP-GSQTSDGQTCR--TACSANP--CFGGRVPCQDLPDGRYQC 73
C+G C++T+ +RC CP G + G+ C+ CS +P C C++L G Y C
Sbjct: 836 CIGGDCINTNGSYRC-LCPQGHRLVGGRKCQDIDECSQDPSLCL-PHGACKNL-QGSYVC 892
Query: 74 GKCPSGF 80
C GF
Sbjct: 893 -VCDEGF 898
Score = 33.1 bits (72), Expect = 4.0
Identities = 16/38 (42%), Positives = 24/38 (63%), Gaps = 5/38 (13%)
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDEC 173
+E +C+ +T P YEC C G+ ++G CVD+DEC
Sbjct: 1006 KEGKCV--NTQPGYECY-CKQGFYYDGNLLECVDVDEC 1040
>BC052263-1|AAH52263.2| 992|Homo sapiens signal peptide, CUB
domain, EGF-like 3 protein.
Length = 992
Score = 66.1 bits (154), Expect = 5e-10
Identities = 66/228 (28%), Positives = 97/228 (42%), Gaps = 32/228 (14%)
Query: 24 CVDTDQG-FRCERCPGSQ-TSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF- 80
C +T +G CE PG + T + + C+ C+ G + C D G +CG C F
Sbjct: 171 CRETPKGGIACECRPGFELTKNQRDCKLTCNYGNG-GCQHTCDDTEQGP-RCG-CHIKFV 227
Query: 81 -HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQCQHVCDAQ-KPC 136
H +G C +C N C + G C +CP G++ D + C+ + + +
Sbjct: 228 LHTDGKTCIE-TCAVNNGGCDSKCHDAAIGVHC-TCPVGFMLQPDRKTCKDIDECRLNNG 285
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSCRNEEXXXXX 194
G + C ++T +EC C GY+ N C D+DEC R CD + C N
Sbjct: 286 GCDHIC--RNTVGSFECS-CKKGYKLLINERNCQDIDECSFDRTCDHI--CVN------- 333
Query: 195 XXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
+G+ G HC DVDEC+ R C G C+NTP
Sbjct: 334 TPGSFQCLCHRGYLLYG----ITHCGDVDECSINRGGCRFG--CINTP 375
Score = 46.8 bits (106), Expect = 3e-04
Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 8/83 (9%)
Query: 95 NTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKPCGRERRCMPKSTSPYYE 152
+ C C+ T KC C +GY GDG+ C+ V C+ + G C+ + Y
Sbjct: 38 DNCHIDAICQNTPRSYKC-ICKSGYTGDGKHCKDVDECEREDNAGCVHDCV--NIPGNYR 94
Query: 153 CEGCPSGYQ--WNGYTCVDMDEC 173
C C G+ +G+ C+D+DEC
Sbjct: 95 CT-CYDGFHLAHDGHNCLDVDEC 116
Score = 33.5 bits (73), Expect = 3.0
Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 14/87 (16%)
Query: 221 DVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLV 280
DVDEC +G NC +C NTP+ SY C+ G Y + C D D
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPR-----------SYKCICKSG--YTGDGKHCKDVDE-C 74
Query: 281 KRCDPSYCRRFNAVCGFGQKCVCNTGW 307
+R D + C +C C G+
Sbjct: 75 EREDNAGCVHDCVNIPGNYRCTCYDGF 101
>Z97832-1|CAI20187.1| 993|Homo sapiens protein ( Human DNA sequence
from clone RP3-329A5 on chromosome 6p21.1-21.33. ).
Length = 993
Score = 65.7 bits (153), Expect = 6e-10
Identities = 66/228 (28%), Positives = 97/228 (42%), Gaps = 32/228 (14%)
Query: 24 CVDTDQG-FRCERCPGSQ-TSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF- 80
C +T +G CE PG + T + + C+ C+ G + C D G +CG C F
Sbjct: 172 CRETPKGGIACECRPGFELTKNQRDCKLTCNYGNG-GCQHTCDDTEQGP-RCG-CHIKFV 228
Query: 81 -HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQCQHVCDAQ-KPC 136
H +G C +C N C + G C +CP G++ D + C+ + + +
Sbjct: 229 LHTDGKTCIE-TCAVNNGGCDSKCHDAATGVHC-TCPVGFMLQPDRKTCKDIDECRLNNG 286
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSCRNEEXXXXX 194
G + C ++T +EC C GY+ N C D+DEC R CD + C N
Sbjct: 287 GCDHIC--RNTVGSFECS-CKKGYKLLINERNCQDIDECSFDRTCDHI--CVN------- 334
Query: 195 XXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
+G+ G HC DVDEC+ R C G C+NTP
Sbjct: 335 TPGSFQCLCHRGYLLYG----ITHCGDVDECSINRGGCRFG--CINTP 376
Score = 46.8 bits (106), Expect = 3e-04
Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 8/83 (9%)
Query: 95 NTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKPCGRERRCMPKSTSPYYE 152
+ C C+ T KC C +GY GDG+ C+ V C+ + G C+ + Y
Sbjct: 38 DNCHIDAICQNTPRSYKC-ICKSGYTGDGKHCKDVDECEREDNAGCVHDCV--NIPGNYR 94
Query: 153 CEGCPSGYQ--WNGYTCVDMDEC 173
C C G+ +G+ C+D+DEC
Sbjct: 95 CT-CYDGFHLAHDGHNCLDVDEC 116
Score = 33.5 bits (73), Expect = 3.0
Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 14/87 (16%)
Query: 221 DVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLV 280
DVDEC +G NC +C NTP+ SY C+ G Y + C D D
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPR-----------SYKCICKSG--YTGDGKHCKDVDE-C 74
Query: 281 KRCDPSYCRRFNAVCGFGQKCVCNTGW 307
+R D + C +C C G+
Sbjct: 75 EREDNAGCVHDCVNIPGNYRCTCYDGF 101
>AY639608-1|AAU08347.1| 993|Homo sapiens signal peptide, CUB and
EGF-like domain containing protein 3 protein.
Length = 993
Score = 65.7 bits (153), Expect = 6e-10
Identities = 66/228 (28%), Positives = 97/228 (42%), Gaps = 32/228 (14%)
Query: 24 CVDTDQG-FRCERCPGSQ-TSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF- 80
C +T +G CE PG + T + + C+ C+ G + C D G +CG C F
Sbjct: 172 CRETPKGGIACECRPGFELTKNQRDCKLTCNYGNG-GCQHTCDDTEQGP-RCG-CHIKFV 228
Query: 81 -HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQCQHVCDAQ-KPC 136
H +G C +C N C + G C +CP G++ D + C+ + + +
Sbjct: 229 LHTDGKTCIE-TCAVNNGGCDSKCHDAATGVHC-TCPVGFMLQPDRKTCKDIDECRLNNG 286
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSCRNEEXXXXX 194
G + C ++T +EC C GY+ N C D+DEC R CD + C N
Sbjct: 287 GCDHIC--RNTVGSFECS-CKKGYKLLINERNCQDIDECSFDRTCDHI--CVN------- 334
Query: 195 XXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
+G+ G HC DVDEC+ R C G C+NTP
Sbjct: 335 TPGSFQCLCHRGYLLYG----ITHCGDVDECSINRGGCRFG--CINTP 376
Score = 46.8 bits (106), Expect = 3e-04
Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 8/83 (9%)
Query: 95 NTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKPCGRERRCMPKSTSPYYE 152
+ C C+ T KC C +GY GDG+ C+ V C+ + G C+ + Y
Sbjct: 38 DNCHIDAICQNTPRSYKC-ICKSGYTGDGKHCKDVDECEREDNAGCVHDCV--NIPGNYR 94
Query: 153 CEGCPSGYQ--WNGYTCVDMDEC 173
C C G+ +G+ C+D+DEC
Sbjct: 95 CT-CYDGFHLAHDGHNCLDVDEC 116
Score = 33.5 bits (73), Expect = 3.0
Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 14/87 (16%)
Query: 221 DVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLV 280
DVDEC +G NC +C NTP+ SY C+ G Y + C D D
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPR-----------SYKCICKSG--YTGDGKHCKDVDE-C 74
Query: 281 KRCDPSYCRRFNAVCGFGQKCVCNTGW 307
+R D + C +C C G+
Sbjct: 75 EREDNAGCVHDCVNIPGNYRCTCYDGF 101
>AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 65.7 bits (153), Expect = 6e-10
Identities = 69/234 (29%), Positives = 84/234 (35%), Gaps = 37/234 (15%)
Query: 48 RTACS--ANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRANT--CFQG-- 100
R CS PC V C + G + CG CP+G+ GNG C I+ C N C
Sbjct: 264 RDECSFQPGPC-STLVQCFNT-QGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPP 321
Query: 101 VSCEETQYGPKCGSCPTGYVGDGRQC--QHVCDAQK-PCGRERRCMPKSTSPYYECEGCP 157
V C T C +CP GY GDGR C +C C + C ST C
Sbjct: 322 VECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASC--SSTLGSLPLCTCL 379
Query: 158 SGYQWNGY---TCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTG--- 211
GY NGY CV + L PC + C GW G
Sbjct: 380 PGYTGNGYGPNGCVQLSNICLSHPCLN-GQC-------IDTVSGYFCKCDSGWTGVNCTE 431
Query: 212 --NERRREHCVDVDECADG----RANCPR---GRLCVNTPQYPSNPVSSLQGSY 256
NE C++ C DG C R G LC Q +S + GS+
Sbjct: 432 NINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQQVCGESLSGINGSF 485
Score = 56.8 bits (131), Expect = 3e-07
Identities = 51/172 (29%), Positives = 68/172 (39%), Gaps = 24/172 (13%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCR--TACSAN--PC-FGGRVPCQDLPDGRYQCGKCP 77
+C +T F C CP +G C C N C V C + P G C CP
Sbjct: 279 QCFNTQGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPPVECVNTP-GSSHCQACP 337
Query: 78 SGFHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGR------QCQH 128
G+ G+G C C + C SC T +C GY G+G Q +
Sbjct: 338 PGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSN 397
Query: 129 VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRPC 179
+C PC +C+ T Y C+ C SG W G C + ++EC L PC
Sbjct: 398 IC-LSHPC-LNGQCI--DTVSGYFCK-CDSG--WTGVNCTENINEC-LSNPC 441
Score = 46.4 bits (105), Expect = 4e-04
Identities = 65/258 (25%), Positives = 95/258 (36%), Gaps = 43/258 (16%)
Query: 69 GRYQCGKCPSGFHGNGVECYRISCRANT---CFQGVSCEET---QYG-PKCGS-CPTGYV 120
G Y C CP +G C + C G+ CE+ Q G PK C G++
Sbjct: 195 GSYSC-HCPPETYGPQCASKYDDCEGGSVARCVHGI-CEDLMREQAGEPKYSCVCDAGWM 252
Query: 121 --GDGRQC---QHVCDAQK-PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECD 174
+ C + C Q PC +C +T + C CP+G+Q NGY C D++EC+
Sbjct: 253 FSPNSPACTLDRDECSFQPGPCSTLVQCF--NTQGSFYCGACPTGWQGNGYICEDINECE 310
Query: 175 LIR-PCD--DLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRAN 231
+ C V C N G++G G C D C+
Sbjct: 311 INNGGCSVAPPVECVN------TPGSSHCQACPPGYQGDGRV-----CTLTDICSVSNGG 359
Query: 232 CPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRF 291
C C +T S P+ + Y G + V + C L +C
Sbjct: 360 CHPDASCSST--LGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQC-------I 410
Query: 292 NAVCGFGQKCVCNTGWTG 309
+ V G+ C C++GWTG
Sbjct: 411 DTVSGY--FCKCDSGWTG 426
Score = 42.3 bits (95), Expect = 0.007
Identities = 41/152 (26%), Positives = 58/152 (38%), Gaps = 16/152 (10%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPD--GRYQCGKCPSGFH 81
CV+T C+ CP DG+ C + GG P G C G+
Sbjct: 324 CVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYT 383
Query: 82 GNGV---ECYRIS--CRANTCFQGVSCEETQYGPKCGSCPTGYVG-DGRQCQHVCDAQKP 135
GNG C ++S C ++ C G C +T G C C +G+ G + + + C P
Sbjct: 384 GNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFC-KCDSGWTGVNCTENINEC-LSNP 440
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC 167
C C+ S + CE C W G C
Sbjct: 441 CLNGGTCVDGVDS--FSCE-CTR--LWTGALC 467
>AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 65.7 bits (153), Expect = 6e-10
Identities = 69/234 (29%), Positives = 84/234 (35%), Gaps = 37/234 (15%)
Query: 48 RTACS--ANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRANT--CFQG-- 100
R CS PC V C + G + CG CP+G+ GNG C I+ C N C
Sbjct: 264 RDECSFQPGPC-STLVQCFNT-QGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPP 321
Query: 101 VSCEETQYGPKCGSCPTGYVGDGRQC--QHVCDAQK-PCGRERRCMPKSTSPYYECEGCP 157
V C T C +CP GY GDGR C +C C + C ST C
Sbjct: 322 VECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASC--SSTLGSLPLCTCL 379
Query: 158 SGYQWNGY---TCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTG--- 211
GY NGY CV + L PC + C GW G
Sbjct: 380 PGYTGNGYGPNGCVQLSNICLSHPCLN-GQC-------IDTVSGYFCKCDSGWTGVNCTE 431
Query: 212 --NERRREHCVDVDECADG----RANCPR---GRLCVNTPQYPSNPVSSLQGSY 256
NE C++ C DG C R G LC Q +S + GS+
Sbjct: 432 NINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQQVCGESLSGINGSF 485
Score = 56.8 bits (131), Expect = 3e-07
Identities = 51/172 (29%), Positives = 68/172 (39%), Gaps = 24/172 (13%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCR--TACSAN--PC-FGGRVPCQDLPDGRYQCGKCP 77
+C +T F C CP +G C C N C V C + P G C CP
Sbjct: 279 QCFNTQGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPPVECVNTP-GSSHCQACP 337
Query: 78 SGFHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGR------QCQH 128
G+ G+G C C + C SC T +C GY G+G Q +
Sbjct: 338 PGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSN 397
Query: 129 VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRPC 179
+C PC +C+ T Y C+ C SG W G C + ++EC L PC
Sbjct: 398 IC-LSHPC-LNGQCI--DTVSGYFCK-CDSG--WTGVNCTENINEC-LSNPC 441
Score = 46.4 bits (105), Expect = 4e-04
Identities = 65/258 (25%), Positives = 95/258 (36%), Gaps = 43/258 (16%)
Query: 69 GRYQCGKCPSGFHGNGVECYRISCRANT---CFQGVSCEET---QYG-PKCGS-CPTGYV 120
G Y C CP +G C + C G+ CE+ Q G PK C G++
Sbjct: 195 GSYSC-HCPPETYGPQCASKYDDCEGGSVARCVHGI-CEDLMREQAGEPKYSCVCDAGWM 252
Query: 121 --GDGRQC---QHVCDAQK-PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECD 174
+ C + C Q PC +C +T + C CP+G+Q NGY C D++EC+
Sbjct: 253 FSPNSPACTLDRDECSFQPGPCSTLVQCF--NTQGSFYCGACPTGWQGNGYICEDINECE 310
Query: 175 LIR-PCD--DLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRAN 231
+ C V C N G++G G C D C+
Sbjct: 311 INNGGCSVAPPVECVN------TPGSSHCQACPPGYQGDGRV-----CTLTDICSVSNGG 359
Query: 232 CPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRF 291
C C +T S P+ + Y G + V + C L +C
Sbjct: 360 CHPDASCSST--LGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQC-------I 410
Query: 292 NAVCGFGQKCVCNTGWTG 309
+ V G+ C C++GWTG
Sbjct: 411 DTVSGY--FCKCDSGWTG 426
Score = 42.3 bits (95), Expect = 0.007
Identities = 41/152 (26%), Positives = 58/152 (38%), Gaps = 16/152 (10%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPD--GRYQCGKCPSGFH 81
CV+T C+ CP DG+ C + GG P G C G+
Sbjct: 324 CVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYT 383
Query: 82 GNGV---ECYRIS--CRANTCFQGVSCEETQYGPKCGSCPTGYVG-DGRQCQHVCDAQKP 135
GNG C ++S C ++ C G C +T G C C +G+ G + + + C P
Sbjct: 384 GNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFC-KCDSGWTGVNCTENINEC-LSNP 440
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC 167
C C+ S + CE C W G C
Sbjct: 441 CLNGGTCVDGVDS--FSCE-CTR--LWTGALC 467
>AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
protein.
Length = 2471
Score = 65.7 bits (153), Expect = 6e-10
Identities = 50/155 (32%), Positives = 65/155 (41%), Gaps = 19/155 (12%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRT---ACSANPCFGGRV--PCQDLPDGRYQC 73
C E +D Q C G+ C T C PC G ++PDG + C
Sbjct: 1273 CSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDG-FIC 1331
Query: 74 GKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQ 133
+CP GF +G C + SC C +G C T GP+C CP+ R C+ C A
Sbjct: 1332 -RCPPGF--SGARC-QSSCGQVKCRKGEQCVHTASGPRC-FCPSP-----RDCESGC-AS 1380
Query: 134 KPCGRERRCMPKSTSPYYECEGCP--SGYQWNGYT 166
PC C P+ PYY C+ P SG + YT
Sbjct: 1381 SPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYT 1415
Score = 63.7 bits (148), Expect = 2e-09
Identities = 50/167 (29%), Positives = 66/167 (39%), Gaps = 13/167 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C+D F C PG QT C + PC G C D + Y C KC +GF
Sbjct: 923 GGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGT-CSDYVNS-YTC-KCQAGF 979
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C ++CF G +C + C CP G+ G C H + + PC
Sbjct: 980 DGVHCENNINECTESSCFNGGTCVDGINSFSC-LCPVGFTGS--FCLHEINECSSHPCLN 1036
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSC 185
E C+ + Y C CP GY G C + PC + +C
Sbjct: 1037 EGTCVDGLGT--YRC-SCPLGY--TGKNCQTLVNLCSRSPCKNKGTC 1078
Score = 61.3 bits (142), Expect = 1e-08
Identities = 52/171 (30%), Positives = 72/171 (42%), Gaps = 14/171 (8%)
Query: 19 CVGE-RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCP 77
C+ + RC+D G++C PG+ + + C++NPC G C D RY C C
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHG--ICMD-GINRYSC-VCS 671
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCG 137
GF G C +N C +G +C G +C CP G Q PC
Sbjct: 672 PGFTGQRCNIDIDECASNPCRKGATCINGVNGFRC-ICPEGPHHPSCYSQVNECLSNPC- 729
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C + Y+C C +G W G C VD +EC L PC + +C N
Sbjct: 730 IHGNCTGGLSG--YKCL-CDAG--WVGINCEVDKNEC-LSNPCQNGGTCDN 774
Score = 60.1 bits (139), Expect = 3e-08
Identities = 79/295 (26%), Positives = 111/295 (37%), Gaps = 49/295 (16%)
Query: 21 GERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C++ GFRC CP G + C +NPC G C G Y+C C +G
Sbjct: 694 GATCINGVNGFRCI-CPEGPHHPSCYSQVNECLSNPCIHGN--CTGGLSG-YKC-LCDAG 748
Query: 80 FHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCG 137
+ G E + C +N C G +C+ G +C +C G+ G CQ D A PC
Sbjct: 749 WVGINCEVDKNECLSNPCQNGGTCDNLVNGYRC-TCKKGF--KGYNCQVNIDECASNPCL 805
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX 197
+ C + Y C C Y G C + PC++ C+
Sbjct: 806 NQGTCFDDISG--YTCH-CVLPY--TGKNCQTVLAPCSPNPCENAAVCKESP-----NFE 855
Query: 198 XXXXXXSQGWRGTGNERRREHC-VDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSY 256
+ GW+G + C +D+DEC C LC NT QGSY
Sbjct: 856 SYTCLCAPGWQG-------QRCTIDIDECIS--KPCMNHGLCHNT-----------QGSY 895
Query: 257 ICVPCGGHYYVNTTRPCFDPDSLVKRC-DPSYCRRFNAVCGFGQKCVCNTGWTGN 310
+C C + D D L C + C + V F C+C G+TG+
Sbjct: 896 MC-ECPPGFSGMDCEEDID-DCLANPCQNGGSC--MDGVNTF--SCLCLPGFTGD 944
Score = 59.3 bits (137), Expect = 5e-08
Identities = 62/228 (27%), Positives = 91/228 (39%), Gaps = 36/228 (15%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSA-NPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C F C+ G +T C C G C +LP G YQC +CP G
Sbjct: 156 GSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGT-CLNLP-GSYQC-QCPQG 212
Query: 80 FHGNGVECYRISCRANTCFQGVSCEET-QYGPKCGSCPTGYVGDGRQCQHVCD--AQKPC 136
F G + + C + C G +C +T + +C +C G+ +G C+ D C
Sbjct: 213 FTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC-NCLPGF--EGSTCERNIDDCPNHRC 269
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRP--CDDLVSCRNEEXXXX 193
C+ + Y C CP QW G C D+DEC L++P C + +C N
Sbjct: 270 QNGGVCVDGVNT--YNCR-CPP--QWTGQFCTEDVDEC-LLQPNACQNGGTCANRNGGYG 323
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVD-VDECADGRANCPRGRLCVN 240
GW G + C + +D+CA A+C G C++
Sbjct: 324 CVCV-------NGWSG-------DDCSENIDDCA--FASCTPGSTCID 355
Score = 58.8 bits (136), Expect = 7e-08
Identities = 75/304 (24%), Positives = 105/304 (34%), Gaps = 36/304 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C D G+ C + QT CS NPC V C++ P+ C G+ G
Sbjct: 810 CFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAV-CKESPNFESYTCLCAPGWQGQ 868
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
C + C C TQ C CP G+ G C+ D PC
Sbjct: 869 RCTIDIDECISKPCMNHGLCHNTQGSYMC-ECPPGF--SGMDCEEDIDDCLANPCQNGGS 925
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
CM + + C C G+ G C DM+EC L PC + +C +
Sbjct: 926 CMDGVNT--FSCL-CLPGF--TGDKCQTDMNEC-LSEPCKNGGTC--SDYVNSYTCKCQA 977
Query: 201 XXXSQGWRGTGNERRREHCVDVDECADGRAN----CP---RGRLCVNTPQYPSNPVSSLQ 253
NE C + C DG + CP G C++ S+ +
Sbjct: 978 GFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNE 1037
Query: 254 GSYICVPCGGHYYVN-----TTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQKCVCNT 305
G+ CV G Y + T + C +LV C S C+ C +C+C +
Sbjct: 1038 GT--CVDGLGTYRCSCPLGYTGKNC---QTLVNLCSRSPCKN-KGTCVQKKAESQCLCPS 1091
Query: 306 GWTG 309
GW G
Sbjct: 1092 GWAG 1095
Score = 58.4 bits (135), Expect = 9e-08
Identities = 81/312 (25%), Positives = 112/312 (35%), Gaps = 39/312 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C+D GF C PG + + C +NPC C D + R+QC CP GF G
Sbjct: 471 CLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNG-QCVDKVN-RFQC-LCPPGFTGP 527
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
+ C + C G C + G +C C TG+ G C+ D PC +
Sbjct: 528 VCQIDIDDCSSTPCLNGAKCIDHPNGYEC-QCATGFT--GVLCEENIDNCDPDPC-HHGQ 583
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRP------CDDLV-----SCRNEE 189
C S Y C C GY G C D +DEC P C DLV +C+
Sbjct: 584 CQDGIDS--YTCI-CNPGYM--GAICSDQIDEC-YSSPCLNDGRCIDLVNGYQCNCQPGT 637
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNER-RREHCVDVDECADGRANCPRGRLCVNTPQYPSNP 248
+ G + R CV R N N + +
Sbjct: 638 SGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATC 697
Query: 249 VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGF-GQKCVCNTGW 307
++ + G P G H+ C+ S V C + C N G G KC+C+ GW
Sbjct: 698 INGVNGFRCICPEGPHH-----PSCY---SQVNECLSNPCIHGNCTGGLSGYKCLCDAGW 749
Query: 308 TGNGTVCGLDRD 319
G C +D++
Sbjct: 750 VGIN--CEVDKN 759
Score = 55.2 bits (127), Expect = 9e-07
Identities = 58/181 (32%), Positives = 74/181 (40%), Gaps = 26/181 (14%)
Query: 19 CVGE-RCVDTDQGFRCERCPGSQTSDG-QTCRTACSANPCFGGRVPCQDLPDGRYQCGKC 76
C+ E CVD +RC CP T QT CS +PC Q + QC C
Sbjct: 1034 CLNEGTCVDGLGTYRCS-CPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAES--QC-LC 1089
Query: 77 PSGFHGNGVECYRISCRANTCFQGVSCEE-TQYGPKC---GS-----CPTGYVGDGRQCQ 127
PSG+ G + +SC +GV E Q+ C G+ CP GY G C+
Sbjct: 1090 PSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGS--YCE 1147
Query: 128 HVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVS 184
D A PC C Y CE C GYQ G C ++DEC +PC + +
Sbjct: 1148 EQLDECASNPCQHGATC--SDFIGGYRCE-CVPGYQ--GVNCEYEVDECQ-NQPCQNGGT 1201
Query: 185 C 185
C
Sbjct: 1202 C 1202
Score = 51.6 bits (118), Expect = 1e-05
Identities = 44/158 (27%), Positives = 66/158 (41%), Gaps = 14/158 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D + C+ G + C+ + CF G C D + + C CP GF
Sbjct: 961 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGT-CVDGINS-FSC-LCPVGF 1017
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G+ C ++ C +C + +C SCP GY G+ CQ + + ++ PC
Sbjct: 1018 TGSFCLHEINECSSHPCLNEGTCVDGLGTYRC-SCPLGYT--GKNCQTLVNLCSRSPCKN 1074
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDL 175
+ C+ K +C CPSG W G C V CD+
Sbjct: 1075 KGTCVQKKAES--QCL-CPSG--WAGAYCDVPNVSCDI 1107
Score = 50.4 bits (115), Expect = 2e-05
Identities = 52/181 (28%), Positives = 73/181 (40%), Gaps = 26/181 (14%)
Query: 16 FKLCV-GERCVDTDQGFRCERCPGSQTSDGQTCRT--ACSANPCFGGRVPCQDLP-DGRY 71
F C G C+D F C CP + G C AC +NPC G + C P +G+Y
Sbjct: 344 FASCTPGSTCIDRVASFSC-MCPEGKA--GLLCHLDDACISNPCHKGAL-CDTNPLNGQY 399
Query: 72 QCGKCPSGFHGNGV-----ECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQC 126
C CP G+ G EC +N C C T C C GY G +
Sbjct: 400 IC-TCPQGYKGADCTEDVDEC--AMANSNPCEHAGKCVNTDGAFHC-ECLKGYAGPRCEM 455
Query: 127 Q-HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVS 184
+ C + PC + C+ K + C C G++ G C ++++EC PC +
Sbjct: 456 DINECHSD-PCQNDATCLDKIGG--FTCL-CMPGFK--GVHCELEINECQ-SNPCVNNGQ 508
Query: 185 C 185
C
Sbjct: 509 C 509
Score = 48.0 bits (109), Expect = 1e-04
Identities = 46/168 (27%), Positives = 64/168 (38%), Gaps = 13/168 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G +C+D G+ C+ G + C +PC G+ CQD D Y C C G+
Sbjct: 544 GAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQ--CQDGIDS-YTC-ICNPGY 599
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
G C ++ C C + G +C +C G G + A PC
Sbjct: 600 MGAICSDQIDECYSSPCLNDGRCIDLVNGYQC-NCQPGTSGVNCEINFDDCASNPC-IHG 657
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
CM Y C C G+ G C +D+DEC PC +C N
Sbjct: 658 ICMDGINR--YSCV-CSPGF--TGQRCNIDIDEC-ASNPCRKGATCIN 699
Score = 44.0 bits (99), Expect = 0.002
Identities = 33/103 (32%), Positives = 42/103 (40%), Gaps = 5/103 (4%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D G+RCE PG Q + + C PC G C DL + ++C CP G
Sbjct: 1161 GATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGT-CIDLVN-HFKC-SCPPGT 1217
Query: 81 HGNGVECYRISC-RANTCFQGVSCEETQYGPKCGSCPTGYVGD 122
G E C R C G C + G C C G+ G+
Sbjct: 1218 RGLLCEENIDDCARGPHCLNGGQCMDRIGGYSC-RCLPGFAGE 1259
Score = 43.2 bits (97), Expect = 0.004
Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 11/102 (10%)
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--A 132
+CP G+ G+ E C +N C G +C + G +C C GY G C++ D
Sbjct: 1136 QCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRC-ECVPGY--QGVNCEYEVDECQ 1192
Query: 133 QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDEC 173
+PC C+ +++C CP G + G C + +D+C
Sbjct: 1193 NQPCQNGGTCI--DLVNHFKC-SCPPGTR--GLLCEENIDDC 1229
>AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
protein.
Length = 2471
Score = 65.7 bits (153), Expect = 6e-10
Identities = 50/155 (32%), Positives = 65/155 (41%), Gaps = 19/155 (12%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRT---ACSANPCFGGRV--PCQDLPDGRYQC 73
C E +D Q C G+ C T C PC G ++PDG + C
Sbjct: 1273 CSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDG-FIC 1331
Query: 74 GKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQ 133
+CP GF +G C + SC C +G C T GP+C CP+ R C+ C A
Sbjct: 1332 -RCPPGF--SGARC-QSSCGQVKCRKGEQCVHTASGPRC-FCPSP-----RDCESGC-AS 1380
Query: 134 KPCGRERRCMPKSTSPYYECEGCP--SGYQWNGYT 166
PC C P+ PYY C+ P SG + YT
Sbjct: 1381 SPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYT 1415
Score = 63.7 bits (148), Expect = 2e-09
Identities = 50/167 (29%), Positives = 66/167 (39%), Gaps = 13/167 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C+D F C PG QT C + PC G C D + Y C KC +GF
Sbjct: 923 GGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGT-CSDYVNS-YTC-KCQAGF 979
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C ++CF G +C + C CP G+ G C H + + PC
Sbjct: 980 DGVHCENNINECTESSCFNGGTCVDGINSFSC-LCPVGFTGS--FCLHEINECSSHPCLN 1036
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSC 185
E C+ + Y C CP GY G C + PC + +C
Sbjct: 1037 EGTCVDGLGT--YRC-SCPLGY--TGKNCQTLVNLCSRSPCKNKGTC 1078
Score = 61.3 bits (142), Expect = 1e-08
Identities = 52/171 (30%), Positives = 72/171 (42%), Gaps = 14/171 (8%)
Query: 19 CVGE-RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCP 77
C+ + RC+D G++C PG+ + + C++NPC G C D RY C C
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHG--ICMD-GINRYSC-VCS 671
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCG 137
GF G C +N C +G +C G +C CP G Q PC
Sbjct: 672 PGFTGQRCNIDIDECASNPCRKGATCINGVNGFRC-ICPEGPHHPSCYSQVNECLSNPC- 729
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C + Y+C C +G W G C VD +EC L PC + +C N
Sbjct: 730 IHGNCTGGLSG--YKCL-CDAG--WVGINCEVDKNEC-LSNPCQNGGTCDN 774
Score = 60.1 bits (139), Expect = 3e-08
Identities = 79/295 (26%), Positives = 111/295 (37%), Gaps = 49/295 (16%)
Query: 21 GERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C++ GFRC CP G + C +NPC G C G Y+C C +G
Sbjct: 694 GATCINGVNGFRCI-CPEGPHHPSCYSQVNECLSNPCIHGN--CTGGLSG-YKC-LCDAG 748
Query: 80 FHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCG 137
+ G E + C +N C G +C+ G +C +C G+ G CQ D A PC
Sbjct: 749 WVGINCEVDKNECLSNPCQNGGTCDNLVNGYRC-TCKKGF--KGYNCQVNIDECASNPCL 805
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX 197
+ C + Y C C Y G C + PC++ C+
Sbjct: 806 NQGTCFDDISG--YTCH-CVLPY--TGKNCQTVLAPCSPNPCENAAVCKESP-----NFE 855
Query: 198 XXXXXXSQGWRGTGNERRREHC-VDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSY 256
+ GW+G + C +D+DEC C LC NT QGSY
Sbjct: 856 SYTCLCAPGWQG-------QRCTIDIDECIS--KPCMNHGLCHNT-----------QGSY 895
Query: 257 ICVPCGGHYYVNTTRPCFDPDSLVKRC-DPSYCRRFNAVCGFGQKCVCNTGWTGN 310
+C C + D D L C + C + V F C+C G+TG+
Sbjct: 896 MC-ECPPGFSGMDCEEDID-DCLANPCQNGGSC--MDGVNTF--SCLCLPGFTGD 944
Score = 59.3 bits (137), Expect = 5e-08
Identities = 62/228 (27%), Positives = 91/228 (39%), Gaps = 36/228 (15%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSA-NPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C F C+ G +T C C G C +LP G YQC +CP G
Sbjct: 156 GSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGT-CLNLP-GSYQC-QCPQG 212
Query: 80 FHGNGVECYRISCRANTCFQGVSCEET-QYGPKCGSCPTGYVGDGRQCQHVCD--AQKPC 136
F G + + C + C G +C +T + +C +C G+ +G C+ D C
Sbjct: 213 FTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC-NCLPGF--EGSTCERNIDDCPNHRC 269
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRP--CDDLVSCRNEEXXXX 193
C+ + Y C CP QW G C D+DEC L++P C + +C N
Sbjct: 270 QNGGVCVDGVNT--YNCR-CPP--QWTGQFCTEDVDEC-LLQPNACQNGGTCANRNGGYG 323
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVD-VDECADGRANCPRGRLCVN 240
GW G + C + +D+CA A+C G C++
Sbjct: 324 CVCV-------NGWSG-------DDCSENIDDCA--FASCTPGSTCID 355
Score = 58.8 bits (136), Expect = 7e-08
Identities = 75/304 (24%), Positives = 105/304 (34%), Gaps = 36/304 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C D G+ C + QT CS NPC V C++ P+ C G+ G
Sbjct: 810 CFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAV-CKESPNFESYTCLCAPGWQGQ 868
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
C + C C TQ C CP G+ G C+ D PC
Sbjct: 869 RCTIDIDECISKPCMNHGLCHNTQGSYMC-ECPPGF--SGMDCEEDIDDCLANPCQNGGS 925
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
CM + + C C G+ G C DM+EC L PC + +C +
Sbjct: 926 CMDGVNT--FSCL-CLPGF--TGDKCQTDMNEC-LSEPCKNGGTC--SDYVNSYTCKCQA 977
Query: 201 XXXSQGWRGTGNERRREHCVDVDECADGRAN----CP---RGRLCVNTPQYPSNPVSSLQ 253
NE C + C DG + CP G C++ S+ +
Sbjct: 978 GFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNE 1037
Query: 254 GSYICVPCGGHYYVN-----TTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQKCVCNT 305
G+ CV G Y + T + C +LV C S C+ C +C+C +
Sbjct: 1038 GT--CVDGLGTYRCSCPLGYTGKNC---QTLVNLCSRSPCKN-KGTCVQKKAESQCLCPS 1091
Query: 306 GWTG 309
GW G
Sbjct: 1092 GWAG 1095
Score = 58.4 bits (135), Expect = 9e-08
Identities = 81/312 (25%), Positives = 112/312 (35%), Gaps = 39/312 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C+D GF C PG + + C +NPC C D + R+QC CP GF G
Sbjct: 471 CLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNG-QCVDKVN-RFQC-LCPPGFTGP 527
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
+ C + C G C + G +C C TG+ G C+ D PC +
Sbjct: 528 VCQIDIDDCSSTPCLNGAKCIDHPNGYEC-QCATGFT--GVLCEENIDNCDPDPC-HHGQ 583
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRP------CDDLV-----SCRNEE 189
C S Y C C GY G C D +DEC P C DLV +C+
Sbjct: 584 CQDGIDS--YTCI-CNPGYM--GAICSDQIDEC-YSSPCLNDGRCIDLVNGYQCNCQPGT 637
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNER-RREHCVDVDECADGRANCPRGRLCVNTPQYPSNP 248
+ G + R CV R N N + +
Sbjct: 638 SGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATC 697
Query: 249 VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGF-GQKCVCNTGW 307
++ + G P G H+ C+ S V C + C N G G KC+C+ GW
Sbjct: 698 INGVNGFRCICPEGPHH-----PSCY---SQVNECLSNPCIHGNCTGGLSGYKCLCDAGW 749
Query: 308 TGNGTVCGLDRD 319
G C +D++
Sbjct: 750 VGIN--CEVDKN 759
Score = 55.2 bits (127), Expect = 9e-07
Identities = 58/181 (32%), Positives = 74/181 (40%), Gaps = 26/181 (14%)
Query: 19 CVGE-RCVDTDQGFRCERCPGSQTSDG-QTCRTACSANPCFGGRVPCQDLPDGRYQCGKC 76
C+ E CVD +RC CP T QT CS +PC Q + QC C
Sbjct: 1034 CLNEGTCVDGLGTYRCS-CPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAES--QC-LC 1089
Query: 77 PSGFHGNGVECYRISCRANTCFQGVSCEE-TQYGPKC---GS-----CPTGYVGDGRQCQ 127
PSG+ G + +SC +GV E Q+ C G+ CP GY G C+
Sbjct: 1090 PSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGS--YCE 1147
Query: 128 HVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVS 184
D A PC C Y CE C GYQ G C ++DEC +PC + +
Sbjct: 1148 EQLDECASNPCQHGATC--SDFIGGYRCE-CVPGYQ--GVNCEYEVDECQ-NQPCQNGGT 1201
Query: 185 C 185
C
Sbjct: 1202 C 1202
Score = 51.6 bits (118), Expect = 1e-05
Identities = 44/158 (27%), Positives = 66/158 (41%), Gaps = 14/158 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D + C+ G + C+ + CF G C D + + C CP GF
Sbjct: 961 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGT-CVDGINS-FSC-LCPVGF 1017
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G+ C ++ C +C + +C SCP GY G+ CQ + + ++ PC
Sbjct: 1018 TGSFCLHEINECSSHPCLNEGTCVDGLGTYRC-SCPLGYT--GKNCQTLVNLCSRSPCKN 1074
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDL 175
+ C+ K +C CPSG W G C V CD+
Sbjct: 1075 KGTCVQKKAES--QCL-CPSG--WAGAYCDVPNVSCDI 1107
Score = 50.4 bits (115), Expect = 2e-05
Identities = 52/181 (28%), Positives = 73/181 (40%), Gaps = 26/181 (14%)
Query: 16 FKLCV-GERCVDTDQGFRCERCPGSQTSDGQTCRT--ACSANPCFGGRVPCQDLP-DGRY 71
F C G C+D F C CP + G C AC +NPC G + C P +G+Y
Sbjct: 344 FASCTPGSTCIDRVASFSC-MCPEGKA--GLLCHLDDACISNPCHKGAL-CDTNPLNGQY 399
Query: 72 QCGKCPSGFHGNGV-----ECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQC 126
C CP G+ G EC +N C C T C C GY G +
Sbjct: 400 IC-TCPQGYKGADCTEDVDEC--AMANSNPCEHAGKCVNTDGAFHC-ECLKGYAGPRCEM 455
Query: 127 Q-HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVS 184
+ C + PC + C+ K + C C G++ G C ++++EC PC +
Sbjct: 456 DINECHSD-PCQNDATCLDKIGG--FTCL-CMPGFK--GVHCELEINECQ-SNPCVNNGQ 508
Query: 185 C 185
C
Sbjct: 509 C 509
Score = 48.0 bits (109), Expect = 1e-04
Identities = 46/168 (27%), Positives = 64/168 (38%), Gaps = 13/168 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G +C+D G+ C+ G + C +PC G+ CQD D Y C C G+
Sbjct: 544 GAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQ--CQDGIDS-YTC-ICNPGY 599
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
G C ++ C C + G +C +C G G + A PC
Sbjct: 600 MGAICSDQIDECYSSPCLNDGRCIDLVNGYQC-NCQPGTSGVNCEINFDDCASNPC-IHG 657
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
CM Y C C G+ G C +D+DEC PC +C N
Sbjct: 658 ICMDGINR--YSCV-CSPGF--TGQRCNIDIDEC-ASNPCRKGATCIN 699
Score = 44.0 bits (99), Expect = 0.002
Identities = 33/103 (32%), Positives = 42/103 (40%), Gaps = 5/103 (4%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D G+RCE PG Q + + C PC G C DL + ++C CP G
Sbjct: 1161 GATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGT-CIDLVN-HFKC-SCPPGT 1217
Query: 81 HGNGVECYRISC-RANTCFQGVSCEETQYGPKCGSCPTGYVGD 122
G E C R C G C + G C C G+ G+
Sbjct: 1218 RGLLCEENIDDCARGPHCLNGGQCMDRIGGYSC-RCLPGFAGE 1259
Score = 43.2 bits (97), Expect = 0.004
Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 11/102 (10%)
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--A 132
+CP G+ G+ E C +N C G +C + G +C C GY G C++ D
Sbjct: 1136 QCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRC-ECVPGY--QGVNCEYEVDECQ 1192
Query: 133 QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDEC 173
+PC C+ +++C CP G + G C + +D+C
Sbjct: 1193 NQPCQNGGTCI--DLVNHFKC-SCPPGTR--GLLCEENIDDC 1229
>AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 65.7 bits (153), Expect = 6e-10
Identities = 69/234 (29%), Positives = 84/234 (35%), Gaps = 37/234 (15%)
Query: 48 RTACS--ANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRANT--CFQG-- 100
R CS PC V C + G + CG CP+G+ GNG C I+ C N C
Sbjct: 264 RDECSFQPGPC-STLVQCFNT-QGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPP 321
Query: 101 VSCEETQYGPKCGSCPTGYVGDGRQC--QHVCDAQK-PCGRERRCMPKSTSPYYECEGCP 157
V C T C +CP GY GDGR C +C C + C ST C
Sbjct: 322 VECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASC--SSTLGSLPLCTCL 379
Query: 158 SGYQWNGY---TCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTG--- 211
GY NGY CV + L PC + C GW G
Sbjct: 380 PGYTGNGYGPNGCVQLSNICLSHPCLN-GQC-------IDTVSGYFCKCDSGWTGVNCTE 431
Query: 212 --NERRREHCVDVDECADG----RANCPR---GRLCVNTPQYPSNPVSSLQGSY 256
NE C++ C DG C R G LC Q +S + GS+
Sbjct: 432 NINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQQVCGESLSGINGSF 485
Score = 56.8 bits (131), Expect = 3e-07
Identities = 51/172 (29%), Positives = 68/172 (39%), Gaps = 24/172 (13%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCR--TACSAN--PC-FGGRVPCQDLPDGRYQCGKCP 77
+C +T F C CP +G C C N C V C + P G C CP
Sbjct: 279 QCFNTQGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPPVECVNTP-GSSHCQACP 337
Query: 78 SGFHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGR------QCQH 128
G+ G+G C C + C SC T +C GY G+G Q +
Sbjct: 338 PGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSN 397
Query: 129 VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRPC 179
+C PC +C+ T Y C+ C SG W G C + ++EC L PC
Sbjct: 398 IC-LSHPC-LNGQCI--DTVSGYFCK-CDSG--WTGVNCTENINEC-LSNPC 441
Score = 46.4 bits (105), Expect = 4e-04
Identities = 65/258 (25%), Positives = 95/258 (36%), Gaps = 43/258 (16%)
Query: 69 GRYQCGKCPSGFHGNGVECYRISCRANT---CFQGVSCEET---QYG-PKCGS-CPTGYV 120
G Y C CP +G C + C G+ CE+ Q G PK C G++
Sbjct: 195 GSYSC-HCPPETYGPQCASKYDDCEGGSVARCVHGI-CEDLMREQAGEPKYSCVCDAGWM 252
Query: 121 --GDGRQC---QHVCDAQK-PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECD 174
+ C + C Q PC +C +T + C CP+G+Q NGY C D++EC+
Sbjct: 253 FSPNSPACTLDRDECSFQPGPCSTLVQCF--NTQGSFYCGACPTGWQGNGYICEDINECE 310
Query: 175 LIR-PCD--DLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRAN 231
+ C V C N G++G G C D C+
Sbjct: 311 INNGGCSVAPPVECVN------TPGSSHCQACPPGYQGDGRV-----CTLTDICSVSNGG 359
Query: 232 CPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRF 291
C C +T S P+ + Y G + V + C L +C
Sbjct: 360 CHPDASCSST--LGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQC-------I 410
Query: 292 NAVCGFGQKCVCNTGWTG 309
+ V G+ C C++GWTG
Sbjct: 411 DTVSGY--FCKCDSGWTG 426
Score = 42.3 bits (95), Expect = 0.007
Identities = 41/152 (26%), Positives = 58/152 (38%), Gaps = 16/152 (10%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPD--GRYQCGKCPSGFH 81
CV+T C+ CP DG+ C + GG P G C G+
Sbjct: 324 CVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYT 383
Query: 82 GNGV---ECYRIS--CRANTCFQGVSCEETQYGPKCGSCPTGYVG-DGRQCQHVCDAQKP 135
GNG C ++S C ++ C G C +T G C C +G+ G + + + C P
Sbjct: 384 GNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFC-KCDSGWTGVNCTENINEC-LSNP 440
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC 167
C C+ S + CE C W G C
Sbjct: 441 CLNGGTCVDGVDS--FSCE-CTR--LWTGALC 467
>AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
protein.
Length = 2471
Score = 65.7 bits (153), Expect = 6e-10
Identities = 50/155 (32%), Positives = 65/155 (41%), Gaps = 19/155 (12%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRT---ACSANPCFGGRV--PCQDLPDGRYQC 73
C E +D Q C G+ C T C PC G ++PDG + C
Sbjct: 1273 CSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDG-FIC 1331
Query: 74 GKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQ 133
+CP GF +G C + SC C +G C T GP+C CP+ R C+ C A
Sbjct: 1332 -RCPPGF--SGARC-QSSCGQVKCRKGEQCVHTASGPRC-FCPSP-----RDCESGC-AS 1380
Query: 134 KPCGRERRCMPKSTSPYYECEGCP--SGYQWNGYT 166
PC C P+ PYY C+ P SG + YT
Sbjct: 1381 SPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYT 1415
Score = 63.7 bits (148), Expect = 2e-09
Identities = 50/167 (29%), Positives = 66/167 (39%), Gaps = 13/167 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C+D F C PG QT C + PC G C D + Y C KC +GF
Sbjct: 923 GGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGT-CSDYVNS-YTC-KCQAGF 979
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C ++CF G +C + C CP G+ G C H + + PC
Sbjct: 980 DGVHCENNINECTESSCFNGGTCVDGINSFSC-LCPVGFTGS--FCLHEINECSSHPCLN 1036
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSC 185
E C+ + Y C CP GY G C + PC + +C
Sbjct: 1037 EGTCVDGLGT--YRC-SCPLGY--TGKNCQTLVNLCSRSPCKNKGTC 1078
Score = 61.3 bits (142), Expect = 1e-08
Identities = 52/171 (30%), Positives = 72/171 (42%), Gaps = 14/171 (8%)
Query: 19 CVGE-RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCP 77
C+ + RC+D G++C PG+ + + C++NPC G C D RY C C
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHG--ICMD-GINRYSC-VCS 671
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCG 137
GF G C +N C +G +C G +C CP G Q PC
Sbjct: 672 PGFTGQRCNIDIDECASNPCRKGATCINGVNGFRC-ICPEGPHHPSCYSQVNECLSNPC- 729
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C + Y+C C +G W G C VD +EC L PC + +C N
Sbjct: 730 IHGNCTGGLSG--YKCL-CDAG--WVGINCEVDKNEC-LSNPCQNGGTCDN 774
Score = 60.1 bits (139), Expect = 3e-08
Identities = 79/295 (26%), Positives = 111/295 (37%), Gaps = 49/295 (16%)
Query: 21 GERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C++ GFRC CP G + C +NPC G C G Y+C C +G
Sbjct: 694 GATCINGVNGFRCI-CPEGPHHPSCYSQVNECLSNPCIHGN--CTGGLSG-YKC-LCDAG 748
Query: 80 FHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCG 137
+ G E + C +N C G +C+ G +C +C G+ G CQ D A PC
Sbjct: 749 WVGINCEVDKNECLSNPCQNGGTCDNLVNGYRC-TCKKGF--KGYNCQVNIDECASNPCL 805
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX 197
+ C + Y C C Y G C + PC++ C+
Sbjct: 806 NQGTCFDDISG--YTCH-CVLPY--TGKNCQTVLAPCSPNPCENAAVCKESP-----NFE 855
Query: 198 XXXXXXSQGWRGTGNERRREHC-VDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSY 256
+ GW+G + C +D+DEC C LC NT QGSY
Sbjct: 856 SYTCLCAPGWQG-------QRCTIDIDECIS--KPCMNHGLCHNT-----------QGSY 895
Query: 257 ICVPCGGHYYVNTTRPCFDPDSLVKRC-DPSYCRRFNAVCGFGQKCVCNTGWTGN 310
+C C + D D L C + C + V F C+C G+TG+
Sbjct: 896 MC-ECPPGFSGMDCEEDID-DCLANPCQNGGSC--MDGVNTF--SCLCLPGFTGD 944
Score = 59.3 bits (137), Expect = 5e-08
Identities = 62/228 (27%), Positives = 91/228 (39%), Gaps = 36/228 (15%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSA-NPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C F C+ G +T C C G C +LP G YQC +CP G
Sbjct: 156 GSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGT-CLNLP-GSYQC-QCPQG 212
Query: 80 FHGNGVECYRISCRANTCFQGVSCEET-QYGPKCGSCPTGYVGDGRQCQHVCD--AQKPC 136
F G + + C + C G +C +T + +C +C G+ +G C+ D C
Sbjct: 213 FTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC-NCLPGF--EGSTCERNIDDCPNHRC 269
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRP--CDDLVSCRNEEXXXX 193
C+ + Y C CP QW G C D+DEC L++P C + +C N
Sbjct: 270 QNGGVCVDGVNT--YNCR-CPP--QWTGQFCTEDVDEC-LLQPNACQNGGTCANRNGGYG 323
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVD-VDECADGRANCPRGRLCVN 240
GW G + C + +D+CA A+C G C++
Sbjct: 324 CVCV-------NGWSG-------DDCSENIDDCA--FASCTPGSTCID 355
Score = 58.8 bits (136), Expect = 7e-08
Identities = 75/304 (24%), Positives = 105/304 (34%), Gaps = 36/304 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C D G+ C + QT CS NPC V C++ P+ C G+ G
Sbjct: 810 CFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAV-CKESPNFESYTCLCAPGWQGQ 868
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
C + C C TQ C CP G+ G C+ D PC
Sbjct: 869 RCTIDIDECISKPCMNHGLCHNTQGSYMC-ECPPGF--SGMDCEEDIDDCLANPCQNGGS 925
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
CM + + C C G+ G C DM+EC L PC + +C +
Sbjct: 926 CMDGVNT--FSCL-CLPGF--TGDKCQTDMNEC-LSEPCKNGGTC--SDYVNSYTCKCQA 977
Query: 201 XXXSQGWRGTGNERRREHCVDVDECADGRAN----CP---RGRLCVNTPQYPSNPVSSLQ 253
NE C + C DG + CP G C++ S+ +
Sbjct: 978 GFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNE 1037
Query: 254 GSYICVPCGGHYYVN-----TTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQKCVCNT 305
G+ CV G Y + T + C +LV C S C+ C +C+C +
Sbjct: 1038 GT--CVDGLGTYRCSCPLGYTGKNC---QTLVNLCSRSPCKN-KGTCVQKKAESQCLCPS 1091
Query: 306 GWTG 309
GW G
Sbjct: 1092 GWAG 1095
Score = 58.4 bits (135), Expect = 9e-08
Identities = 81/312 (25%), Positives = 112/312 (35%), Gaps = 39/312 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C+D GF C PG + + C +NPC C D + R+QC CP GF G
Sbjct: 471 CLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNG-QCVDKVN-RFQC-LCPPGFTGP 527
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
+ C + C G C + G +C C TG+ G C+ D PC +
Sbjct: 528 VCQIDIDDCSSTPCLNGAKCIDHPNGYEC-QCATGFT--GVLCEENIDNCDPDPC-HHGQ 583
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRP------CDDLV-----SCRNEE 189
C S Y C C GY G C D +DEC P C DLV +C+
Sbjct: 584 CQDGIDS--YTCI-CNPGYM--GAICSDQIDEC-YSSPCLNDGRCIDLVNGYQCNCQPGT 637
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNER-RREHCVDVDECADGRANCPRGRLCVNTPQYPSNP 248
+ G + R CV R N N + +
Sbjct: 638 SGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATC 697
Query: 249 VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGF-GQKCVCNTGW 307
++ + G P G H+ C+ S V C + C N G G KC+C+ GW
Sbjct: 698 INGVNGFRCICPEGPHH-----PSCY---SQVNECLSNPCIHGNCTGGLSGYKCLCDAGW 749
Query: 308 TGNGTVCGLDRD 319
G C +D++
Sbjct: 750 VGIN--CEVDKN 759
Score = 55.2 bits (127), Expect = 9e-07
Identities = 58/181 (32%), Positives = 74/181 (40%), Gaps = 26/181 (14%)
Query: 19 CVGE-RCVDTDQGFRCERCPGSQTSDG-QTCRTACSANPCFGGRVPCQDLPDGRYQCGKC 76
C+ E CVD +RC CP T QT CS +PC Q + QC C
Sbjct: 1034 CLNEGTCVDGLGTYRCS-CPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAES--QC-LC 1089
Query: 77 PSGFHGNGVECYRISCRANTCFQGVSCEE-TQYGPKC---GS-----CPTGYVGDGRQCQ 127
PSG+ G + +SC +GV E Q+ C G+ CP GY G C+
Sbjct: 1090 PSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGS--YCE 1147
Query: 128 HVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVS 184
D A PC C Y CE C GYQ G C ++DEC +PC + +
Sbjct: 1148 EQLDECASNPCQHGATC--SDFIGGYRCE-CVPGYQ--GVNCEYEVDECQ-NQPCQNGGT 1201
Query: 185 C 185
C
Sbjct: 1202 C 1202
Score = 51.6 bits (118), Expect = 1e-05
Identities = 44/158 (27%), Positives = 66/158 (41%), Gaps = 14/158 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D + C+ G + C+ + CF G C D + + C CP GF
Sbjct: 961 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGT-CVDGINS-FSC-LCPVGF 1017
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G+ C ++ C +C + +C SCP GY G+ CQ + + ++ PC
Sbjct: 1018 TGSFCLHEINECSSHPCLNEGTCVDGLGTYRC-SCPLGYT--GKNCQTLVNLCSRSPCKN 1074
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDL 175
+ C+ K +C CPSG W G C V CD+
Sbjct: 1075 KGTCVQKKAES--QCL-CPSG--WAGAYCDVPNVSCDI 1107
Score = 50.4 bits (115), Expect = 2e-05
Identities = 52/181 (28%), Positives = 73/181 (40%), Gaps = 26/181 (14%)
Query: 16 FKLCV-GERCVDTDQGFRCERCPGSQTSDGQTCRT--ACSANPCFGGRVPCQDLP-DGRY 71
F C G C+D F C CP + G C AC +NPC G + C P +G+Y
Sbjct: 344 FASCTPGSTCIDRVASFSC-MCPEGKA--GLLCHLDDACISNPCHKGAL-CDTNPLNGQY 399
Query: 72 QCGKCPSGFHGNGV-----ECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQC 126
C CP G+ G EC +N C C T C C GY G +
Sbjct: 400 IC-TCPQGYKGADCTEDVDEC--AMANSNPCEHAGKCVNTDGAFHC-ECLKGYAGPRCEM 455
Query: 127 Q-HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVS 184
+ C + PC + C+ K + C C G++ G C ++++EC PC +
Sbjct: 456 DINECHSD-PCQNDATCLDKIGG--FTCL-CMPGFK--GVHCELEINECQ-SNPCVNNGQ 508
Query: 185 C 185
C
Sbjct: 509 C 509
Score = 48.0 bits (109), Expect = 1e-04
Identities = 46/168 (27%), Positives = 64/168 (38%), Gaps = 13/168 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G +C+D G+ C+ G + C +PC G+ CQD D Y C C G+
Sbjct: 544 GAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQ--CQDGIDS-YTC-ICNPGY 599
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
G C ++ C C + G +C +C G G + A PC
Sbjct: 600 MGAICSDQIDECYSSPCLNDGRCIDLVNGYQC-NCQPGTSGVNCEINFDDCASNPC-IHG 657
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
CM Y C C G+ G C +D+DEC PC +C N
Sbjct: 658 ICMDGINR--YSCV-CSPGF--TGQRCNIDIDEC-ASNPCRKGATCIN 699
Score = 44.0 bits (99), Expect = 0.002
Identities = 33/103 (32%), Positives = 42/103 (40%), Gaps = 5/103 (4%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D G+RCE PG Q + + C PC G C DL + ++C CP G
Sbjct: 1161 GATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGT-CIDLVN-HFKC-SCPPGT 1217
Query: 81 HGNGVECYRISC-RANTCFQGVSCEETQYGPKCGSCPTGYVGD 122
G E C R C G C + G C C G+ G+
Sbjct: 1218 RGLLCEENIDDCARGPHCLNGGQCMDRIGGYSC-RCLPGFAGE 1259
Score = 43.2 bits (97), Expect = 0.004
Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 11/102 (10%)
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--A 132
+CP G+ G+ E C +N C G +C + G +C C GY G C++ D
Sbjct: 1136 QCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRC-ECVPGY--QGVNCEYEVDECQ 1192
Query: 133 QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDEC 173
+PC C+ +++C CP G + G C + +D+C
Sbjct: 1193 NQPCQNGGTCI--DLVNHFKC-SCPPGTR--GLLCEENIDDC 1229
>AF452494-1|AAN76808.1| 993|Homo sapiens CUB and EGF containing
protein protein.
Length = 993
Score = 65.7 bits (153), Expect = 6e-10
Identities = 66/228 (28%), Positives = 97/228 (42%), Gaps = 32/228 (14%)
Query: 24 CVDTDQG-FRCERCPGSQ-TSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF- 80
C +T +G CE PG + T + + C+ C+ G + C D G +CG C F
Sbjct: 172 CRETPKGGIACECRPGFELTKNQRDCKLTCNYGNG-GCQHTCDDTEQGP-RCG-CHIKFV 228
Query: 81 -HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQCQHVCDAQ-KPC 136
H +G C +C N C + G C +CP G++ D + C+ + + +
Sbjct: 229 LHTDGKTCIE-TCAVNNGGCDSKCHDAATGVHC-TCPVGFMLQPDRKTCKDIDECRLNNG 286
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSCRNEEXXXXX 194
G + C ++T +EC C GY+ N C D+DEC R CD + C N
Sbjct: 287 GCDHIC--RNTVGSFECS-CKKGYKLLINERNCQDIDECSFDRTCDHI--CVN------- 334
Query: 195 XXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
+G+ G HC DVDEC+ R C G C+NTP
Sbjct: 335 TPGSFQCLCHRGYLLYG----ITHCGDVDECSINRGGCRFG--CINTP 376
Score = 46.8 bits (106), Expect = 3e-04
Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 8/83 (9%)
Query: 95 NTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKPCGRERRCMPKSTSPYYE 152
+ C C+ T KC C +GY GDG+ C+ V C+ + G C+ + Y
Sbjct: 38 DNCHIDAICQNTPRSYKC-ICKSGYTGDGKHCKDVDECEREDNAGCVHDCV--NIPGNYR 94
Query: 153 CEGCPSGYQ--WNGYTCVDMDEC 173
C C G+ +G+ C+D+DEC
Sbjct: 95 CT-CYDGFHLAHDGHNCLDVDEC 116
Score = 33.5 bits (73), Expect = 3.0
Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 14/87 (16%)
Query: 221 DVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLV 280
DVDEC +G NC +C NTP+ SY C+ G Y + C D D
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPR-----------SYKCICKSG--YTGDGKHCKDVDE-C 74
Query: 281 KRCDPSYCRRFNAVCGFGQKCVCNTGW 307
+R D + C +C C G+
Sbjct: 75 EREDNAGCVHDCVNIPGNYRCTCYDGF 101
>AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein.
Length = 2471
Score = 65.7 bits (153), Expect = 6e-10
Identities = 50/155 (32%), Positives = 65/155 (41%), Gaps = 19/155 (12%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRT---ACSANPCFGGRV--PCQDLPDGRYQC 73
C E +D Q C G+ C T C PC G ++PDG + C
Sbjct: 1273 CSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDG-FIC 1331
Query: 74 GKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQ 133
+CP GF +G C + SC C +G C T GP+C CP+ R C+ C A
Sbjct: 1332 -RCPPGF--SGARC-QSSCGQVKCRKGEQCVHTASGPRC-FCPSP-----RDCESGC-AS 1380
Query: 134 KPCGRERRCMPKSTSPYYECEGCP--SGYQWNGYT 166
PC C P+ PYY C+ P SG + YT
Sbjct: 1381 SPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYT 1415
Score = 63.7 bits (148), Expect = 2e-09
Identities = 50/167 (29%), Positives = 66/167 (39%), Gaps = 13/167 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C+D F C PG QT C + PC G C D + Y C KC +GF
Sbjct: 923 GGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGT-CSDYVNS-YTC-KCQAGF 979
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C ++CF G +C + C CP G+ G C H + + PC
Sbjct: 980 DGVHCENNINECTESSCFNGGTCVDGINSFSC-LCPVGFTGS--FCLHEINECSSHPCLN 1036
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSC 185
E C+ + Y C CP GY G C + PC + +C
Sbjct: 1037 EGTCVDGLGT--YRC-SCPLGY--TGKNCQTLVNLCSRSPCKNKGTC 1078
Score = 61.3 bits (142), Expect = 1e-08
Identities = 52/171 (30%), Positives = 72/171 (42%), Gaps = 14/171 (8%)
Query: 19 CVGE-RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCP 77
C+ + RC+D G++C PG+ + + C++NPC G C D RY C C
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHG--ICMD-GINRYSC-VCS 671
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCG 137
GF G C +N C +G +C G +C CP G Q PC
Sbjct: 672 PGFTGQRCNIDIDECASNPCRKGATCINGVNGFRC-ICPEGPHHPSCYSQVNECLSNPC- 729
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C + Y+C C +G W G C VD +EC L PC + +C N
Sbjct: 730 IHGNCTGGLSG--YKCL-CDAG--WVGINCEVDKNEC-LSNPCQNGGTCDN 774
Score = 60.1 bits (139), Expect = 3e-08
Identities = 79/295 (26%), Positives = 111/295 (37%), Gaps = 49/295 (16%)
Query: 21 GERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C++ GFRC CP G + C +NPC G C G Y+C C +G
Sbjct: 694 GATCINGVNGFRCI-CPEGPHHPSCYSQVNECLSNPCIHGN--CTGGLSG-YKC-LCDAG 748
Query: 80 FHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCG 137
+ G E + C +N C G +C+ G +C +C G+ G CQ D A PC
Sbjct: 749 WVGINCEVDKNECLSNPCQNGGTCDNLVNGYRC-TCKKGF--KGYNCQVNIDECASNPCL 805
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX 197
+ C + Y C C Y G C + PC++ C+
Sbjct: 806 NQGTCFDDISG--YTCH-CVLPY--TGKNCQTVLAPCSPNPCENAAVCKESP-----NFE 855
Query: 198 XXXXXXSQGWRGTGNERRREHC-VDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSY 256
+ GW+G + C +D+DEC C LC NT QGSY
Sbjct: 856 SYTCLCAPGWQG-------QRCTIDIDECIS--KPCMNHGLCHNT-----------QGSY 895
Query: 257 ICVPCGGHYYVNTTRPCFDPDSLVKRC-DPSYCRRFNAVCGFGQKCVCNTGWTGN 310
+C C + D D L C + C + V F C+C G+TG+
Sbjct: 896 MC-ECPPGFSGMDCEEDID-DCLANPCQNGGSC--MDGVNTF--SCLCLPGFTGD 944
Score = 58.8 bits (136), Expect = 7e-08
Identities = 75/304 (24%), Positives = 105/304 (34%), Gaps = 36/304 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C D G+ C + QT CS NPC V C++ P+ C G+ G
Sbjct: 810 CFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAV-CKESPNFESYTCLCAPGWQGQ 868
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
C + C C TQ C CP G+ G C+ D PC
Sbjct: 869 RCTIDIDECISKPCMNHGLCHNTQGSYMC-ECPPGF--SGMDCEEDIDDCLANPCQNGGS 925
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
CM + + C C G+ G C DM+EC L PC + +C +
Sbjct: 926 CMDGVNT--FSCL-CLPGF--TGDKCQTDMNEC-LSEPCKNGGTC--SDYVNSYTCKCQA 977
Query: 201 XXXSQGWRGTGNERRREHCVDVDECADGRAN----CP---RGRLCVNTPQYPSNPVSSLQ 253
NE C + C DG + CP G C++ S+ +
Sbjct: 978 GFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNE 1037
Query: 254 GSYICVPCGGHYYVN-----TTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQKCVCNT 305
G+ CV G Y + T + C +LV C S C+ C +C+C +
Sbjct: 1038 GT--CVDGLGTYRCSCPLGYTGKNC---QTLVNLCSRSPCKN-KGTCVQKKAESQCLCPS 1091
Query: 306 GWTG 309
GW G
Sbjct: 1092 GWAG 1095
Score = 58.4 bits (135), Expect = 9e-08
Identities = 81/312 (25%), Positives = 112/312 (35%), Gaps = 39/312 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C+D GF C PG + + C +NPC C D + R+QC CP GF G
Sbjct: 471 CLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNG-QCVDKVN-RFQC-LCPPGFTGP 527
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
+ C + C G C + G +C C TG+ G C+ D PC +
Sbjct: 528 VCQIDIDDCSSTPCLNGAKCIDHPNGYEC-QCATGFT--GVLCEENIDNCDPDPC-HHGQ 583
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRP------CDDLV-----SCRNEE 189
C S Y C C GY G C D +DEC P C DLV +C+
Sbjct: 584 CQDGIDS--YTCI-CNPGYM--GAICSDQIDEC-YSSPCLNDGRCIDLVNGYQCNCQPGT 637
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNER-RREHCVDVDECADGRANCPRGRLCVNTPQYPSNP 248
+ G + R CV R N N + +
Sbjct: 638 SGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATC 697
Query: 249 VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGF-GQKCVCNTGW 307
++ + G P G H+ C+ S V C + C N G G KC+C+ GW
Sbjct: 698 INGVNGFRCICPEGPHH-----PSCY---SQVNECLSNPCIHGNCTGGLSGYKCLCDAGW 749
Query: 308 TGNGTVCGLDRD 319
G C +D++
Sbjct: 750 VGIN--CEVDKN 759
Score = 55.2 bits (127), Expect = 9e-07
Identities = 61/228 (26%), Positives = 90/228 (39%), Gaps = 36/228 (15%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSA-NPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C F C+ G +T C C G C +LP G YQC +C G
Sbjct: 156 GSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGT-CLNLP-GSYQC-QCLQG 212
Query: 80 FHGNGVECYRISCRANTCFQGVSCEET-QYGPKCGSCPTGYVGDGRQCQHVCD--AQKPC 136
F G + + C + C G +C +T + +C +C G+ +G C+ D C
Sbjct: 213 FTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC-NCLPGF--EGSTCERNIDDCPNHRC 269
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRP--CDDLVSCRNEEXXXX 193
C+ + Y C CP QW G C D+DEC L++P C + +C N
Sbjct: 270 QNGGVCVDGVNT--YNCR-CPP--QWTGQFCTEDVDEC-LLQPNACQNGGTCANRNGGYG 323
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVD-VDECADGRANCPRGRLCVN 240
GW G + C + +D+CA A+C G C++
Sbjct: 324 CVCV-------NGWSG-------DDCSENIDDCA--FASCTPGSTCID 355
Score = 55.2 bits (127), Expect = 9e-07
Identities = 58/181 (32%), Positives = 74/181 (40%), Gaps = 26/181 (14%)
Query: 19 CVGE-RCVDTDQGFRCERCPGSQTSDG-QTCRTACSANPCFGGRVPCQDLPDGRYQCGKC 76
C+ E CVD +RC CP T QT CS +PC Q + QC C
Sbjct: 1034 CLNEGTCVDGLGTYRCS-CPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAES--QC-LC 1089
Query: 77 PSGFHGNGVECYRISCRANTCFQGVSCEE-TQYGPKC---GS-----CPTGYVGDGRQCQ 127
PSG+ G + +SC +GV E Q+ C G+ CP GY G C+
Sbjct: 1090 PSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGS--YCE 1147
Query: 128 HVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVS 184
D A PC C Y CE C GYQ G C ++DEC +PC + +
Sbjct: 1148 EQLDECASNPCQHGATC--SDFIGGYRCE-CVPGYQ--GVNCEYEVDECQ-NQPCQNGGT 1201
Query: 185 C 185
C
Sbjct: 1202 C 1202
Score = 51.6 bits (118), Expect = 1e-05
Identities = 44/158 (27%), Positives = 66/158 (41%), Gaps = 14/158 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D + C+ G + C+ + CF G C D + + C CP GF
Sbjct: 961 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGT-CVDGINS-FSC-LCPVGF 1017
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G+ C ++ C +C + +C SCP GY G+ CQ + + ++ PC
Sbjct: 1018 TGSFCLHEINECSSHPCLNEGTCVDGLGTYRC-SCPLGYT--GKNCQTLVNLCSRSPCKN 1074
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDL 175
+ C+ K +C CPSG W G C V CD+
Sbjct: 1075 KGTCVQKKAES--QCL-CPSG--WAGAYCDVPNVSCDI 1107
Score = 50.4 bits (115), Expect = 2e-05
Identities = 52/181 (28%), Positives = 73/181 (40%), Gaps = 26/181 (14%)
Query: 16 FKLCV-GERCVDTDQGFRCERCPGSQTSDGQTCRT--ACSANPCFGGRVPCQDLP-DGRY 71
F C G C+D F C CP + G C AC +NPC G + C P +G+Y
Sbjct: 344 FASCTPGSTCIDRVASFSC-MCPEGKA--GLLCHLDDACISNPCHKGAL-CDTNPLNGQY 399
Query: 72 QCGKCPSGFHGNGV-----ECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQC 126
C CP G+ G EC +N C C T C C GY G +
Sbjct: 400 IC-TCPQGYKGADCTEDVDEC--AMANSNPCEHAGKCVNTDGAFHC-ECLKGYAGPRCEM 455
Query: 127 Q-HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVS 184
+ C + PC + C+ K + C C G++ G C ++++EC PC +
Sbjct: 456 DINECHSD-PCQNDATCLDKIGG--FTCL-CMPGFK--GVHCELEINECQ-SNPCVNNGQ 508
Query: 185 C 185
C
Sbjct: 509 C 509
Score = 48.0 bits (109), Expect = 1e-04
Identities = 46/168 (27%), Positives = 64/168 (38%), Gaps = 13/168 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G +C+D G+ C+ G + C +PC G+ CQD D Y C C G+
Sbjct: 544 GAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQ--CQDGIDS-YTC-ICNPGY 599
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
G C ++ C C + G +C +C G G + A PC
Sbjct: 600 MGAICSDQIDECYSSPCLNDGRCIDLVNGYQC-NCQPGTSGVNCEINFDDCASNPC-IHG 657
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
CM Y C C G+ G C +D+DEC PC +C N
Sbjct: 658 ICMDGINR--YSCV-CSPGF--TGQRCNIDIDEC-ASNPCRKGATCIN 699
Score = 44.0 bits (99), Expect = 0.002
Identities = 33/103 (32%), Positives = 42/103 (40%), Gaps = 5/103 (4%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D G+RCE PG Q + + C PC G C DL + ++C CP G
Sbjct: 1161 GATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGT-CIDLVN-HFKC-SCPPGT 1217
Query: 81 HGNGVECYRISC-RANTCFQGVSCEETQYGPKCGSCPTGYVGD 122
G E C R C G C + G C C G+ G+
Sbjct: 1218 RGLLCEENIDDCARGPHCLNGGQCMDRIGGYSC-RCLPGFAGE 1259
Score = 43.2 bits (97), Expect = 0.004
Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 11/102 (10%)
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--A 132
+CP G+ G+ E C +N C G +C + G +C C GY G C++ D
Sbjct: 1136 QCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRC-ECVPGY--QGVNCEYEVDECQ 1192
Query: 133 QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDEC 173
+PC C+ +++C CP G + G C + +D+C
Sbjct: 1193 NQPCQNGGTCI--DLVNHFKC-SCPPGTR--GLLCEENIDDC 1229
>AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein.
Length = 2471
Score = 65.7 bits (153), Expect = 6e-10
Identities = 50/155 (32%), Positives = 65/155 (41%), Gaps = 19/155 (12%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRT---ACSANPCFGGRV--PCQDLPDGRYQC 73
C E +D Q C G+ C T C PC G ++PDG + C
Sbjct: 1273 CSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDG-FIC 1331
Query: 74 GKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQ 133
+CP GF +G C + SC C +G C T GP+C CP+ R C+ C A
Sbjct: 1332 -RCPPGF--SGARC-QSSCGQVKCRKGEQCVHTASGPRC-FCPSP-----RDCESGC-AS 1380
Query: 134 KPCGRERRCMPKSTSPYYECEGCP--SGYQWNGYT 166
PC C P+ PYY C+ P SG + YT
Sbjct: 1381 SPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYT 1415
Score = 63.7 bits (148), Expect = 2e-09
Identities = 50/167 (29%), Positives = 66/167 (39%), Gaps = 13/167 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C+D F C PG QT C + PC G C D + Y C KC +GF
Sbjct: 923 GGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGT-CSDYVNS-YTC-KCQAGF 979
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C ++CF G +C + C CP G+ G C H + + PC
Sbjct: 980 DGVHCENNINECTESSCFNGGTCVDGINSFSC-LCPVGFTGS--FCLHEINECSSHPCLN 1036
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSC 185
E C+ + Y C CP GY G C + PC + +C
Sbjct: 1037 EGTCVDGLGT--YRC-SCPLGY--TGKNCQTLVNLCSRSPCKNKGTC 1078
Score = 61.3 bits (142), Expect = 1e-08
Identities = 52/171 (30%), Positives = 72/171 (42%), Gaps = 14/171 (8%)
Query: 19 CVGE-RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCP 77
C+ + RC+D G++C PG+ + + C++NPC G C D RY C C
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHG--ICMD-GINRYSC-VCS 671
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCG 137
GF G C +N C +G +C G +C CP G Q PC
Sbjct: 672 PGFTGQRCNIDIDECASNPCRKGATCINGVNGFRC-ICPEGPHHPSCYSQVNECLSNPC- 729
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C + Y+C C +G W G C VD +EC L PC + +C N
Sbjct: 730 IHGNCTGGLSG--YKCL-CDAG--WVGINCEVDKNEC-LSNPCQNGGTCDN 774
Score = 60.1 bits (139), Expect = 3e-08
Identities = 79/295 (26%), Positives = 111/295 (37%), Gaps = 49/295 (16%)
Query: 21 GERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C++ GFRC CP G + C +NPC G C G Y+C C +G
Sbjct: 694 GATCINGVNGFRCI-CPEGPHHPSCYSQVNECLSNPCIHGN--CTGGLSG-YKC-LCDAG 748
Query: 80 FHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCG 137
+ G E + C +N C G +C+ G +C +C G+ G CQ D A PC
Sbjct: 749 WVGINCEVDKNECLSNPCQNGGTCDNLVNGYRC-TCKKGF--KGYNCQVNIDECASNPCL 805
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX 197
+ C + Y C C Y G C + PC++ C+
Sbjct: 806 NQGTCFDDISG--YTCH-CVLPY--TGKNCQTVLAPCSPNPCENAAVCKESP-----NFE 855
Query: 198 XXXXXXSQGWRGTGNERRREHC-VDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSY 256
+ GW+G + C +D+DEC C LC NT QGSY
Sbjct: 856 SYTCLCAPGWQG-------QRCTIDIDECIS--KPCMNHGLCHNT-----------QGSY 895
Query: 257 ICVPCGGHYYVNTTRPCFDPDSLVKRC-DPSYCRRFNAVCGFGQKCVCNTGWTGN 310
+C C + D D L C + C + V F C+C G+TG+
Sbjct: 896 MC-ECPPGFSGMDCEEDID-DCLANPCQNGGSC--MDGVNTF--SCLCLPGFTGD 944
Score = 59.3 bits (137), Expect = 5e-08
Identities = 62/228 (27%), Positives = 91/228 (39%), Gaps = 36/228 (15%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSA-NPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C F C+ G +T C C G C +LP G YQC +CP G
Sbjct: 156 GSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGT-CLNLP-GSYQC-QCPQG 212
Query: 80 FHGNGVECYRISCRANTCFQGVSCEET-QYGPKCGSCPTGYVGDGRQCQHVCD--AQKPC 136
F G + + C + C G +C +T + +C +C G+ +G C+ D C
Sbjct: 213 FTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC-NCLPGF--EGSTCERNIDDCPNHRC 269
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRP--CDDLVSCRNEEXXXX 193
C+ + Y C CP QW G C D+DEC L++P C + +C N
Sbjct: 270 QNGGVCVDGVNT--YNCR-CPP--QWTGQFCTEDVDEC-LLQPNACQNGGTCANRNGGYG 323
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVD-VDECADGRANCPRGRLCVN 240
GW G + C + +D+CA A+C G C++
Sbjct: 324 CVCV-------NGWSG-------DDCSENIDDCA--FASCTPGSTCID 355
Score = 58.8 bits (136), Expect = 7e-08
Identities = 75/304 (24%), Positives = 105/304 (34%), Gaps = 36/304 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C D G+ C + QT CS NPC V C++ P+ C G+ G
Sbjct: 810 CFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAV-CKESPNFESYTCLCAPGWQGQ 868
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
C + C C TQ C CP G+ G C+ D PC
Sbjct: 869 RCTIDIDECISKPCMNHGLCHNTQGSYMC-ECPPGF--SGMDCEEDIDDCLANPCQNGGS 925
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
CM + + C C G+ G C DM+EC L PC + +C +
Sbjct: 926 CMDGVNT--FSCL-CLPGF--TGDKCQTDMNEC-LSEPCKNGGTC--SDYVNSYTCKCQA 977
Query: 201 XXXSQGWRGTGNERRREHCVDVDECADGRAN----CP---RGRLCVNTPQYPSNPVSSLQ 253
NE C + C DG + CP G C++ S+ +
Sbjct: 978 GFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNE 1037
Query: 254 GSYICVPCGGHYYVN-----TTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQKCVCNT 305
G+ CV G Y + T + C +LV C S C+ C +C+C +
Sbjct: 1038 GT--CVDGLGTYRCSCPLGYTGKNC---QTLVNLCSRSPCKN-KGTCVQKKAESQCLCPS 1091
Query: 306 GWTG 309
GW G
Sbjct: 1092 GWAG 1095
Score = 58.4 bits (135), Expect = 9e-08
Identities = 81/312 (25%), Positives = 112/312 (35%), Gaps = 39/312 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C+D GF C PG + + C +NPC C D + R+QC CP GF G
Sbjct: 471 CLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNG-QCVDKVN-RFQC-LCPPGFTGP 527
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
+ C + C G C + G +C C TG+ G C+ D PC +
Sbjct: 528 VCQIDIDDCSSTPCLNGAKCIDHPNGYEC-QCATGFT--GVLCEENIDNCDPDPC-HHGQ 583
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRP------CDDLV-----SCRNEE 189
C S Y C C GY G C D +DEC P C DLV +C+
Sbjct: 584 CQDGIDS--YTCI-CNPGYM--GAICSDQIDEC-YSSPCLNDGRCIDLVNGYQCNCQPGT 637
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNER-RREHCVDVDECADGRANCPRGRLCVNTPQYPSNP 248
+ G + R CV R N N + +
Sbjct: 638 SGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATC 697
Query: 249 VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGF-GQKCVCNTGW 307
++ + G P G H+ C+ S V C + C N G G KC+C+ GW
Sbjct: 698 INGVNGFRCICPEGPHH-----PSCY---SQVNECLSNPCIHGNCTGGLSGYKCLCDAGW 749
Query: 308 TGNGTVCGLDRD 319
G C +D++
Sbjct: 750 VGIN--CEVDKN 759
Score = 55.2 bits (127), Expect = 9e-07
Identities = 58/181 (32%), Positives = 74/181 (40%), Gaps = 26/181 (14%)
Query: 19 CVGE-RCVDTDQGFRCERCPGSQTSDG-QTCRTACSANPCFGGRVPCQDLPDGRYQCGKC 76
C+ E CVD +RC CP T QT CS +PC Q + QC C
Sbjct: 1034 CLNEGTCVDGLGTYRCS-CPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAES--QC-LC 1089
Query: 77 PSGFHGNGVECYRISCRANTCFQGVSCEE-TQYGPKC---GS-----CPTGYVGDGRQCQ 127
PSG+ G + +SC +GV E Q+ C G+ CP GY G C+
Sbjct: 1090 PSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGS--YCE 1147
Query: 128 HVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVS 184
D A PC C Y CE C GYQ G C ++DEC +PC + +
Sbjct: 1148 EQLDECASNPCQHGATC--SDFIGGYRCE-CVPGYQ--GVNCEYEVDECQ-NQPCQNGGT 1201
Query: 185 C 185
C
Sbjct: 1202 C 1202
Score = 51.6 bits (118), Expect = 1e-05
Identities = 44/158 (27%), Positives = 66/158 (41%), Gaps = 14/158 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D + C+ G + C+ + CF G C D + + C CP GF
Sbjct: 961 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGT-CVDGINS-FSC-LCPVGF 1017
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G+ C ++ C +C + +C SCP GY G+ CQ + + ++ PC
Sbjct: 1018 TGSFCLHEINECSSHPCLNEGTCVDGLGTYRC-SCPLGYT--GKNCQTLVNLCSRSPCKN 1074
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDL 175
+ C+ K +C CPSG W G C V CD+
Sbjct: 1075 KGTCVQKKAES--QCL-CPSG--WAGAYCDVPNVSCDI 1107
Score = 50.4 bits (115), Expect = 2e-05
Identities = 52/181 (28%), Positives = 73/181 (40%), Gaps = 26/181 (14%)
Query: 16 FKLCV-GERCVDTDQGFRCERCPGSQTSDGQTCRT--ACSANPCFGGRVPCQDLP-DGRY 71
F C G C+D F C CP + G C AC +NPC G + C P +G+Y
Sbjct: 344 FASCTPGSTCIDRVASFSC-MCPEGKA--GLLCHLDDACISNPCHKGAL-CDTNPLNGQY 399
Query: 72 QCGKCPSGFHGNGV-----ECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQC 126
C CP G+ G EC +N C C T C C GY G +
Sbjct: 400 IC-TCPQGYKGADCTEDVDEC--AMANSNPCEHAGKCVNTDGAFHC-ECLKGYAGPRCEM 455
Query: 127 Q-HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVS 184
+ C + PC + C+ K + C C G++ G C ++++EC PC +
Sbjct: 456 DINECHSD-PCQNDATCLDKIGG--FTCL-CMPGFK--GVHCELEINECQ-SNPCVNNGQ 508
Query: 185 C 185
C
Sbjct: 509 C 509
Score = 48.0 bits (109), Expect = 1e-04
Identities = 46/168 (27%), Positives = 64/168 (38%), Gaps = 13/168 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G +C+D G+ C+ G + C +PC G+ CQD D Y C C G+
Sbjct: 544 GAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQ--CQDGIDS-YTC-ICNPGY 599
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
G C ++ C C + G +C +C G G + A PC
Sbjct: 600 MGAICSDQIDECYSSPCLNDGRCIDLVNGYQC-NCQPGTSGVNCEINFDDCASNPC-IHG 657
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
CM Y C C G+ G C +D+DEC PC +C N
Sbjct: 658 ICMDGINR--YSCV-CSPGF--TGQRCNIDIDEC-ASNPCRKGATCIN 699
Score = 44.0 bits (99), Expect = 0.002
Identities = 33/103 (32%), Positives = 42/103 (40%), Gaps = 5/103 (4%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D G+RCE PG Q + + C PC G C DL + ++C CP G
Sbjct: 1161 GATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGT-CIDLVN-HFKC-SCPPGT 1217
Query: 81 HGNGVECYRISC-RANTCFQGVSCEETQYGPKCGSCPTGYVGD 122
G E C R C G C + G C C G+ G+
Sbjct: 1218 RGLLCEENIDDCARGPHCLNGGQCMDRIGGYSC-RCLPGFAGE 1259
Score = 43.2 bits (97), Expect = 0.004
Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 11/102 (10%)
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--A 132
+CP G+ G+ E C +N C G +C + G +C C GY G C++ D
Sbjct: 1136 QCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRC-ECVPGY--QGVNCEYEVDECQ 1192
Query: 133 QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDEC 173
+PC C+ +++C CP G + G C + +D+C
Sbjct: 1193 NQPCQNGGTCI--DLVNHFKC-SCPPGTR--GLLCEENIDDC 1229
>AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitamin
B12 receptor protein.
Length = 3494
Score = 65.7 bits (153), Expect = 6e-10
Identities = 69/234 (29%), Positives = 84/234 (35%), Gaps = 37/234 (15%)
Query: 48 RTACS--ANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRANT--CFQG-- 100
R CS PC V C + G + CG CP+G+ GNG C I+ C N C
Sbjct: 135 RDECSFQPGPC-STLVQCFNT-QGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPP 192
Query: 101 VSCEETQYGPKCGSCPTGYVGDGRQC--QHVCDAQK-PCGRERRCMPKSTSPYYECEGCP 157
V C T C +CP GY GDGR C +C C + C ST C
Sbjct: 193 VECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASC--SSTLGSLPLCTCL 250
Query: 158 SGYQWNGY---TCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTG--- 211
GY NGY CV + L PC + C GW G
Sbjct: 251 PGYTGNGYGPNGCVQLSNICLSHPCLN-GQC-------IDTVSGYFCKCDSGWTGVNCTE 302
Query: 212 --NERRREHCVDVDECADG----RANCPR---GRLCVNTPQYPSNPVSSLQGSY 256
NE C++ C DG C R G LC Q +S + GS+
Sbjct: 303 NINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQQVCGESLSGINGSF 356
Score = 56.8 bits (131), Expect = 3e-07
Identities = 51/172 (29%), Positives = 68/172 (39%), Gaps = 24/172 (13%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCR--TACSAN--PC-FGGRVPCQDLPDGRYQCGKCP 77
+C +T F C CP +G C C N C V C + P G C CP
Sbjct: 150 QCFNTQGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPPVECVNTP-GSSHCQACP 208
Query: 78 SGFHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGR------QCQH 128
G+ G+G C C + C SC T +C GY G+G Q +
Sbjct: 209 PGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSN 268
Query: 129 VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRPC 179
+C PC +C+ T Y C+ C SG W G C + ++EC L PC
Sbjct: 269 IC-LSHPC-LNGQCI--DTVSGYFCK-CDSG--WTGVNCTENINEC-LSNPC 312
Score = 47.2 bits (107), Expect = 2e-04
Identities = 65/258 (25%), Positives = 94/258 (36%), Gaps = 43/258 (16%)
Query: 69 GRYQCGKCPSGFHGNGVECYRISCRANT---CFQGVSCEET---QYG-PKCGS-CPTGYV 120
G Y C CP +G C + C G+ CE+ Q G PK C G++
Sbjct: 66 GSYSC-HCPPETYGPQCASKYDDCEGGSVARCVHGI-CEDLMREQAGEPKYSCVCDAGWM 123
Query: 121 GDGRQ--C---QHVCDAQK-PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECD 174
C + C Q PC +C +T + C CP+G+Q NGY C D++EC+
Sbjct: 124 SSPNSPACTLDRDECSFQPGPCSTLVQCF--NTQGSFYCGACPTGWQGNGYICEDINECE 181
Query: 175 LIR-PCD--DLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRAN 231
+ C V C N G++G G C D C+
Sbjct: 182 INNGGCSVAPPVECVN------TPGSSHCQACPPGYQGDGRV-----CTLTDICSVSNGG 230
Query: 232 CPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRF 291
C C +T S P+ + Y G + V + C L +C
Sbjct: 231 CHPDASCSST--LGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQC-------I 281
Query: 292 NAVCGFGQKCVCNTGWTG 309
+ V G+ C C++GWTG
Sbjct: 282 DTVSGY--FCKCDSGWTG 297
Score = 42.3 bits (95), Expect = 0.007
Identities = 41/152 (26%), Positives = 58/152 (38%), Gaps = 16/152 (10%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPD--GRYQCGKCPSGFH 81
CV+T C+ CP DG+ C + GG P G C G+
Sbjct: 195 CVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYT 254
Query: 82 GNGV---ECYRIS--CRANTCFQGVSCEETQYGPKCGSCPTGYVG-DGRQCQHVCDAQKP 135
GNG C ++S C ++ C G C +T G C C +G+ G + + + C P
Sbjct: 255 GNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFC-KCDSGWTGVNCTENINEC-LSNP 311
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC 167
C C+ S + CE C W G C
Sbjct: 312 CLNGGTCVDGVDS--FSCE-CTR--LWTGALC 338
>AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12
receptor precursor protein.
Length = 3623
Score = 65.7 bits (153), Expect = 6e-10
Identities = 69/234 (29%), Positives = 84/234 (35%), Gaps = 37/234 (15%)
Query: 48 RTACS--ANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRANT--CFQG-- 100
R CS PC V C + G + CG CP+G+ GNG C I+ C N C
Sbjct: 264 RDECSFQPGPC-STLVQCFNT-QGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPP 321
Query: 101 VSCEETQYGPKCGSCPTGYVGDGRQC--QHVCDAQK-PCGRERRCMPKSTSPYYECEGCP 157
V C T C +CP GY GDGR C +C C + C ST C
Sbjct: 322 VECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASC--SSTLGSLPLCTCL 379
Query: 158 SGYQWNGY---TCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTG--- 211
GY NGY CV + L PC + C GW G
Sbjct: 380 PGYTGNGYGPNGCVQLSNICLSHPCLN-GQC-------IDTVSGYFCKCDSGWTGVNCTE 431
Query: 212 --NERRREHCVDVDECADG----RANCPR---GRLCVNTPQYPSNPVSSLQGSY 256
NE C++ C DG C R G LC Q +S + GS+
Sbjct: 432 NINECLSNPCLNGGTCVDGVDSFSCECTRLWTGALCQVPQQVCGESLSGINGSF 485
Score = 56.8 bits (131), Expect = 3e-07
Identities = 51/172 (29%), Positives = 68/172 (39%), Gaps = 24/172 (13%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCR--TACSAN--PC-FGGRVPCQDLPDGRYQCGKCP 77
+C +T F C CP +G C C N C V C + P G C CP
Sbjct: 279 QCFNTQGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPPVECVNTP-GSSHCQACP 337
Query: 78 SGFHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGR------QCQH 128
G+ G+G C C + C SC T +C GY G+G Q +
Sbjct: 338 PGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSN 397
Query: 129 VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRPC 179
+C PC +C+ T Y C+ C SG W G C + ++EC L PC
Sbjct: 398 IC-LSHPC-LNGQCI--DTVSGYFCK-CDSG--WTGVNCTENINEC-LSNPC 441
Score = 47.2 bits (107), Expect = 2e-04
Identities = 65/258 (25%), Positives = 94/258 (36%), Gaps = 43/258 (16%)
Query: 69 GRYQCGKCPSGFHGNGVECYRISCRANT---CFQGVSCEET---QYG-PKCGS-CPTGYV 120
G Y C CP +G C + C G+ CE+ Q G PK C G++
Sbjct: 195 GSYSC-HCPPETYGPQCASKYDDCEGGSVARCVHGI-CEDLMREQAGEPKYSCVCDAGWM 252
Query: 121 GDGRQ--C---QHVCDAQK-PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECD 174
C + C Q PC +C +T + C CP+G+Q NGY C D++EC+
Sbjct: 253 SSPNSPACTLDRDECSFQPGPCSTLVQCF--NTQGSFYCGACPTGWQGNGYICEDINECE 310
Query: 175 LIR-PCD--DLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRAN 231
+ C V C N G++G G C D C+
Sbjct: 311 INNGGCSVAPPVECVN------TPGSSHCQACPPGYQGDGRV-----CTLTDICSVSNGG 359
Query: 232 CPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRF 291
C C +T S P+ + Y G + V + C L +C
Sbjct: 360 CHPDASCSST--LGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQC-------I 410
Query: 292 NAVCGFGQKCVCNTGWTG 309
+ V G+ C C++GWTG
Sbjct: 411 DTVSGY--FCKCDSGWTG 426
Score = 42.3 bits (95), Expect = 0.007
Identities = 41/152 (26%), Positives = 58/152 (38%), Gaps = 16/152 (10%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPD--GRYQCGKCPSGFH 81
CV+T C+ CP DG+ C + GG P G C G+
Sbjct: 324 CVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYT 383
Query: 82 GNGV---ECYRIS--CRANTCFQGVSCEETQYGPKCGSCPTGYVG-DGRQCQHVCDAQKP 135
GNG C ++S C ++ C G C +T G C C +G+ G + + + C P
Sbjct: 384 GNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFC-KCDSGWTGVNCTENINEC-LSNP 440
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC 167
C C+ S + CE C W G C
Sbjct: 441 CLNGGTCVDGVDS--FSCE-CTR--LWTGALC 467
>Z98047-1|CAI19628.1| 703|Homo sapiens fibulin 1 protein.
Length = 703
Score = 64.9 bits (151), Expect = 1e-09
Identities = 70/243 (28%), Positives = 102/243 (41%), Gaps = 41/243 (16%)
Query: 20 VGERCVDTDQGFRCER----CPGSQ--TSDGQTC----RTACSANPCFGGRVPCQDLPDG 69
+G C++T+ + C++ C +G C A A PC G C + P G
Sbjct: 321 IGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGH-RCVNSP-G 378
Query: 70 RYQCGKCPSGFHGNGVECYRISCRANTCFQ------GVSCEETQYGPKCGSCPTGY--VG 121
++C +C +G++ +G+ R+ N C + G CE T C SC G+
Sbjct: 379 SFRC-ECKTGYYFDGIS--RMCVDVNECQRYPGRLCGHKCENTLGSYLC-SCSVGFRLSV 434
Query: 122 DGRQCQHVCD-AQKPCGRERRCMPKSTSPYYECEGCPSGYQWN---GYTCVDMDECDLIR 177
DGR C+ + + + PC +E C S Y+C C GYQ + G TC D+DEC L
Sbjct: 435 DGRSCEDINECSSSPCSQE--CANVYGS--YQCY-CRRGYQLSDVDGVTCEDIDECAL-- 487
Query: 178 PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRL 237
P + C S G+R N R +C D+DEC G NC
Sbjct: 488 PTGGHI-C--SYRCINIPGSFQCSCPSSGYRLAPNGR---NCQDIDECVTGIHNCSINET 541
Query: 238 CVN 240
C N
Sbjct: 542 CFN 544
Score = 63.3 bits (147), Expect = 3e-09
Identities = 82/316 (25%), Positives = 125/316 (39%), Gaps = 56/316 (17%)
Query: 56 CFGG---RVPCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-C--RANTCFQGVSCEETQ 107
C GG + C+D D C C G+ +GV C ++ C +++C G SC T
Sbjct: 180 CRGGGPCKQQCRDTGD-EVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTV 237
Query: 108 YGPKC---GSCPTGY-VGDGRQCQHVCDAQKPCGRERRCMP----KSTSPYYECEG---C 156
+C SC TGY + + C+ + + + C+P ++T + C C
Sbjct: 238 GSFRCQRDSSCGTGYELTEDNSCKDIDECESGI---HNCLPDFICQNTLGSFRCRPKLQC 294
Query: 157 PSGYQWNGY-TCVDMDEC-DLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNER 214
SG+ + C+D++EC + PC +C N E RG
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCG-----RGYHLNE 349
Query: 215 RREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCF 274
CVDVDECA C +G CVN+P GS+ C G+Y+ +R C
Sbjct: 350 EGTRCVDVDECAPPAEPCGKGHRCVNSP-----------GSFRCECKTGYYFDGISRMCV 398
Query: 275 DPDSLVKRCDPSYCRRF-NAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQL-PCNE 332
D + C+R+ +C G KC G G +DG E + C+
Sbjct: 399 DVNE---------CQRYPGRLC--GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 333 PRCKKDNCPDVSNSGQ 348
C ++ C +V S Q
Sbjct: 448 SPCSQE-CANVYGSYQ 462
Score = 57.2 bits (132), Expect = 2e-07
Identities = 57/196 (29%), Positives = 86/196 (43%), Gaps = 32/196 (16%)
Query: 5 SMGDAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTAC-SANPCFGGRVP 62
S D +T C +GE C++T FRC+R T T +C + C G
Sbjct: 213 SCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHN 272
Query: 63 CQDLPD-------GRYQCG---KCPSGF----HGNGVECYRISCRANTCFQGVSCEETQY 108
C LPD G ++C +C SGF GN ++ + C G +C T+
Sbjct: 273 C--LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEG 330
Query: 109 GPKC----GSCPTGY--VGDGRQCQHVCDA---QKPCGRERRCMPKSTSPYYECEGCPSG 159
C +C GY +G +C V + +PCG+ RC+ S + CE C +G
Sbjct: 331 SYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGS--FRCE-CKTG 387
Query: 160 YQWNGYT--CVDMDEC 173
Y ++G + CVD++EC
Sbjct: 388 YYFDGISRMCVDVNEC 403
Score = 52.4 bits (120), Expect = 6e-06
Identities = 63/199 (31%), Positives = 84/199 (42%), Gaps = 29/199 (14%)
Query: 8 DAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPC--FGGRV--- 61
D P + C G RCV++ FRCE C DG + R N C + GR+
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCE-CKTGYYFDGIS-RMCVDVNECQRYPGRLCGH 413
Query: 62 PCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTG 118
C++ G Y C C GF +G C I+ C ++ C Q C YG C G
Sbjct: 414 KCENTL-GSYLCS-CSVGFRLSVDGRSCEDINECSSSPCSQ--ECANV-YGSYQCYCRRG 468
Query: 119 YV---GDGRQCQHVCDAQKPCGRE---RRCMPKSTSPYYECEGCPS-GYQW--NGYTCVD 169
Y DG C+ + + P G RC+ S ++C CPS GY+ NG C D
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS--FQCS-CPSSGYRLAPNGRNCQD 525
Query: 170 MDECDL-IRPCDDLVSCRN 187
+DEC I C +C N
Sbjct: 526 IDECVTGIHNCSINETCFN 544
>Z95331-3|CAI41717.1| 703|Homo sapiens fibulin 1 protein.
Length = 703
Score = 64.9 bits (151), Expect = 1e-09
Identities = 70/243 (28%), Positives = 102/243 (41%), Gaps = 41/243 (16%)
Query: 20 VGERCVDTDQGFRCER----CPGSQ--TSDGQTC----RTACSANPCFGGRVPCQDLPDG 69
+G C++T+ + C++ C +G C A A PC G C + P G
Sbjct: 321 IGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGH-RCVNSP-G 378
Query: 70 RYQCGKCPSGFHGNGVECYRISCRANTCFQ------GVSCEETQYGPKCGSCPTGY--VG 121
++C +C +G++ +G+ R+ N C + G CE T C SC G+
Sbjct: 379 SFRC-ECKTGYYFDGIS--RMCVDVNECQRYPGRLCGHKCENTLGSYLC-SCSVGFRLSV 434
Query: 122 DGRQCQHVCD-AQKPCGRERRCMPKSTSPYYECEGCPSGYQWN---GYTCVDMDECDLIR 177
DGR C+ + + + PC +E C S Y+C C GYQ + G TC D+DEC L
Sbjct: 435 DGRSCEDINECSSSPCSQE--CANVYGS--YQCY-CRRGYQLSDVDGVTCEDIDECAL-- 487
Query: 178 PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRL 237
P + C S G+R N R +C D+DEC G NC
Sbjct: 488 PTGGHI-C--SYRCINIPGSFQCSCPSSGYRLAPNGR---NCQDIDECVTGIHNCSINET 541
Query: 238 CVN 240
C N
Sbjct: 542 CFN 544
Score = 63.3 bits (147), Expect = 3e-09
Identities = 82/316 (25%), Positives = 125/316 (39%), Gaps = 56/316 (17%)
Query: 56 CFGG---RVPCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-C--RANTCFQGVSCEETQ 107
C GG + C+D D C C G+ +GV C ++ C +++C G SC T
Sbjct: 180 CRGGGPCKQQCRDTGD-EVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTV 237
Query: 108 YGPKC---GSCPTGY-VGDGRQCQHVCDAQKPCGRERRCMP----KSTSPYYECEG---C 156
+C SC TGY + + C+ + + + C+P ++T + C C
Sbjct: 238 GSFRCQRDSSCGTGYELTEDNSCKDIDECESGI---HNCLPDFICQNTLGSFRCRPKLQC 294
Query: 157 PSGYQWNGY-TCVDMDEC-DLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNER 214
SG+ + C+D++EC + PC +C N E RG
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCG-----RGYHLNE 349
Query: 215 RREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCF 274
CVDVDECA C +G CVN+P GS+ C G+Y+ +R C
Sbjct: 350 EGTRCVDVDECAPPAEPCGKGHRCVNSP-----------GSFRCECKTGYYFDGISRMCV 398
Query: 275 DPDSLVKRCDPSYCRRF-NAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQL-PCNE 332
D + C+R+ +C G KC G G +DG E + C+
Sbjct: 399 DVNE---------CQRYPGRLC--GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 333 PRCKKDNCPDVSNSGQ 348
C ++ C +V S Q
Sbjct: 448 SPCSQE-CANVYGSYQ 462
Score = 57.2 bits (132), Expect = 2e-07
Identities = 57/196 (29%), Positives = 86/196 (43%), Gaps = 32/196 (16%)
Query: 5 SMGDAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTAC-SANPCFGGRVP 62
S D +T C +GE C++T FRC+R T T +C + C G
Sbjct: 213 SCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHN 272
Query: 63 CQDLPD-------GRYQCG---KCPSGF----HGNGVECYRISCRANTCFQGVSCEETQY 108
C LPD G ++C +C SGF GN ++ + C G +C T+
Sbjct: 273 C--LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEG 330
Query: 109 GPKC----GSCPTGY--VGDGRQCQHVCDA---QKPCGRERRCMPKSTSPYYECEGCPSG 159
C +C GY +G +C V + +PCG+ RC+ S + CE C +G
Sbjct: 331 SYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGS--FRCE-CKTG 387
Query: 160 YQWNGYT--CVDMDEC 173
Y ++G + CVD++EC
Sbjct: 388 YYFDGISRMCVDVNEC 403
Score = 52.4 bits (120), Expect = 6e-06
Identities = 63/199 (31%), Positives = 84/199 (42%), Gaps = 29/199 (14%)
Query: 8 DAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPC--FGGRV--- 61
D P + C G RCV++ FRCE C DG + R N C + GR+
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCE-CKTGYYFDGIS-RMCVDVNECQRYPGRLCGH 413
Query: 62 PCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTG 118
C++ G Y C C GF +G C I+ C ++ C Q C YG C G
Sbjct: 414 KCENTL-GSYLCS-CSVGFRLSVDGRSCEDINECSSSPCSQ--ECANV-YGSYQCYCRRG 468
Query: 119 YV---GDGRQCQHVCDAQKPCGRE---RRCMPKSTSPYYECEGCPS-GYQW--NGYTCVD 169
Y DG C+ + + P G RC+ S ++C CPS GY+ NG C D
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS--FQCS-CPSSGYRLAPNGRNCQD 525
Query: 170 MDECDL-IRPCDDLVSCRN 187
+DEC I C +C N
Sbjct: 526 IDECVTGIHNCSINETCFN 544
>X53743-1|CAA37772.1| 683|Homo sapiens fibulin-1 C protein.
Length = 683
Score = 64.9 bits (151), Expect = 1e-09
Identities = 70/243 (28%), Positives = 102/243 (41%), Gaps = 41/243 (16%)
Query: 20 VGERCVDTDQGFRCER----CPGSQ--TSDGQTC----RTACSANPCFGGRVPCQDLPDG 69
+G C++T+ + C++ C +G C A A PC G C + P G
Sbjct: 321 IGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGH-RCVNSP-G 378
Query: 70 RYQCGKCPSGFHGNGVECYRISCRANTCFQ------GVSCEETQYGPKCGSCPTGY--VG 121
++C +C +G++ +G+ R+ N C + G CE T C SC G+
Sbjct: 379 SFRC-ECKTGYYFDGIS--RMCVDVNECQRYPGRLCGHKCENTLGSYLC-SCSVGFRLSV 434
Query: 122 DGRQCQHVCD-AQKPCGRERRCMPKSTSPYYECEGCPSGYQWN---GYTCVDMDECDLIR 177
DGR C+ + + + PC +E C S Y+C C GYQ + G TC D+DEC L
Sbjct: 435 DGRSCEDINECSSSPCSQE--CANVYGS--YQCY-CRRGYQLSDVDGVTCEDIDECAL-- 487
Query: 178 PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRL 237
P + C S G+R N R +C D+DEC G NC
Sbjct: 488 PTGGHI-C--SYRCINIPGSFQCSCPSSGYRLAPNGR---NCQDIDECVTGIHNCSINET 541
Query: 238 CVN 240
C N
Sbjct: 542 CFN 544
Score = 63.3 bits (147), Expect = 3e-09
Identities = 82/316 (25%), Positives = 125/316 (39%), Gaps = 56/316 (17%)
Query: 56 CFGG---RVPCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-C--RANTCFQGVSCEETQ 107
C GG + C+D D C C G+ +GV C ++ C +++C G SC T
Sbjct: 180 CRGGGPCKQQCRDTGD-EVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTV 237
Query: 108 YGPKC---GSCPTGY-VGDGRQCQHVCDAQKPCGRERRCMP----KSTSPYYECEG---C 156
+C SC TGY + + C+ + + + C+P ++T + C C
Sbjct: 238 GSFRCQRDSSCGTGYELTEDNSCKDIDECESGI---HNCLPDFICQNTLGSFRCRPKLQC 294
Query: 157 PSGYQWNGY-TCVDMDEC-DLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNER 214
SG+ + C+D++EC + PC +C N E RG
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCG-----RGYHLNE 349
Query: 215 RREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCF 274
CVDVDECA C +G CVN+P GS+ C G+Y+ +R C
Sbjct: 350 EGTRCVDVDECAPPAEPCGKGHRCVNSP-----------GSFRCECKTGYYFDGISRMCV 398
Query: 275 DPDSLVKRCDPSYCRRF-NAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQL-PCNE 332
D + C+R+ +C G KC G G +DG E + C+
Sbjct: 399 DVNE---------CQRYPGRLC--GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 333 PRCKKDNCPDVSNSGQ 348
C ++ C +V S Q
Sbjct: 448 SPCSQE-CANVYGSYQ 462
Score = 57.2 bits (132), Expect = 2e-07
Identities = 57/196 (29%), Positives = 86/196 (43%), Gaps = 32/196 (16%)
Query: 5 SMGDAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTAC-SANPCFGGRVP 62
S D +T C +GE C++T FRC+R T T +C + C G
Sbjct: 213 SCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHN 272
Query: 63 CQDLPD-------GRYQCG---KCPSGF----HGNGVECYRISCRANTCFQGVSCEETQY 108
C LPD G ++C +C SGF GN ++ + C G +C T+
Sbjct: 273 C--LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEG 330
Query: 109 GPKC----GSCPTGY--VGDGRQCQHVCDA---QKPCGRERRCMPKSTSPYYECEGCPSG 159
C +C GY +G +C V + +PCG+ RC+ S + CE C +G
Sbjct: 331 SYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGS--FRCE-CKTG 387
Query: 160 YQWNGYT--CVDMDEC 173
Y ++G + CVD++EC
Sbjct: 388 YYFDGISRMCVDVNEC 403
Score = 52.4 bits (120), Expect = 6e-06
Identities = 63/199 (31%), Positives = 84/199 (42%), Gaps = 29/199 (14%)
Query: 8 DAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPC--FGGRV--- 61
D P + C G RCV++ FRCE C DG + R N C + GR+
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCE-CKTGYYFDGIS-RMCVDVNECQRYPGRLCGH 413
Query: 62 PCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTG 118
C++ G Y C C GF +G C I+ C ++ C Q C YG C G
Sbjct: 414 KCENTL-GSYLCS-CSVGFRLSVDGRSCEDINECSSSPCSQ--ECANV-YGSYQCYCRRG 468
Query: 119 YV---GDGRQCQHVCDAQKPCGRE---RRCMPKSTSPYYECEGCPS-GYQW--NGYTCVD 169
Y DG C+ + + P G RC+ S ++C CPS GY+ NG C D
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS--FQCS-CPSSGYRLAPNGRNCQD 525
Query: 170 MDECDL-IRPCDDLVSCRN 187
+DEC I C +C N
Sbjct: 526 IDECVTGIHNCSINETCFN 544
>X53742-1|CAA37771.1| 601|Homo sapiens fibulin-1 B protein.
Length = 601
Score = 64.9 bits (151), Expect = 1e-09
Identities = 70/243 (28%), Positives = 102/243 (41%), Gaps = 41/243 (16%)
Query: 20 VGERCVDTDQGFRCER----CPGSQ--TSDGQTC----RTACSANPCFGGRVPCQDLPDG 69
+G C++T+ + C++ C +G C A A PC G C + P G
Sbjct: 321 IGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGH-RCVNSP-G 378
Query: 70 RYQCGKCPSGFHGNGVECYRISCRANTCFQ------GVSCEETQYGPKCGSCPTGY--VG 121
++C +C +G++ +G+ R+ N C + G CE T C SC G+
Sbjct: 379 SFRC-ECKTGYYFDGIS--RMCVDVNECQRYPGRLCGHKCENTLGSYLC-SCSVGFRLSV 434
Query: 122 DGRQCQHVCD-AQKPCGRERRCMPKSTSPYYECEGCPSGYQWN---GYTCVDMDECDLIR 177
DGR C+ + + + PC +E C S Y+C C GYQ + G TC D+DEC L
Sbjct: 435 DGRSCEDINECSSSPCSQE--CANVYGS--YQCY-CRRGYQLSDVDGVTCEDIDECAL-- 487
Query: 178 PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRL 237
P + C S G+R N R +C D+DEC G NC
Sbjct: 488 PTGGHI-C--SYRCINIPGSFQCSCPSSGYRLAPNGR---NCQDIDECVTGIHNCSINET 541
Query: 238 CVN 240
C N
Sbjct: 542 CFN 544
Score = 63.3 bits (147), Expect = 3e-09
Identities = 82/316 (25%), Positives = 125/316 (39%), Gaps = 56/316 (17%)
Query: 56 CFGG---RVPCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-C--RANTCFQGVSCEETQ 107
C GG + C+D D C C G+ +GV C ++ C +++C G SC T
Sbjct: 180 CRGGGPCKQQCRDTGD-EVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTV 237
Query: 108 YGPKC---GSCPTGY-VGDGRQCQHVCDAQKPCGRERRCMP----KSTSPYYECEG---C 156
+C SC TGY + + C+ + + + C+P ++T + C C
Sbjct: 238 GSFRCQRDSSCGTGYELTEDNSCKDIDECESGI---HNCLPDFICQNTLGSFRCRPKLQC 294
Query: 157 PSGYQWNGY-TCVDMDEC-DLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNER 214
SG+ + C+D++EC + PC +C N E RG
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCG-----RGYHLNE 349
Query: 215 RREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCF 274
CVDVDECA C +G CVN+P GS+ C G+Y+ +R C
Sbjct: 350 EGTRCVDVDECAPPAEPCGKGHRCVNSP-----------GSFRCECKTGYYFDGISRMCV 398
Query: 275 DPDSLVKRCDPSYCRRF-NAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQL-PCNE 332
D + C+R+ +C G KC G G +DG E + C+
Sbjct: 399 DVNE---------CQRYPGRLC--GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 333 PRCKKDNCPDVSNSGQ 348
C ++ C +V S Q
Sbjct: 448 SPCSQE-CANVYGSYQ 462
Score = 57.2 bits (132), Expect = 2e-07
Identities = 57/196 (29%), Positives = 86/196 (43%), Gaps = 32/196 (16%)
Query: 5 SMGDAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTAC-SANPCFGGRVP 62
S D +T C +GE C++T FRC+R T T +C + C G
Sbjct: 213 SCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHN 272
Query: 63 CQDLPD-------GRYQCG---KCPSGF----HGNGVECYRISCRANTCFQGVSCEETQY 108
C LPD G ++C +C SGF GN ++ + C G +C T+
Sbjct: 273 C--LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEG 330
Query: 109 GPKC----GSCPTGY--VGDGRQCQHVCDA---QKPCGRERRCMPKSTSPYYECEGCPSG 159
C +C GY +G +C V + +PCG+ RC+ S + CE C +G
Sbjct: 331 SYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGS--FRCE-CKTG 387
Query: 160 YQWNGYT--CVDMDEC 173
Y ++G + CVD++EC
Sbjct: 388 YYFDGISRMCVDVNEC 403
Score = 52.4 bits (120), Expect = 6e-06
Identities = 63/199 (31%), Positives = 84/199 (42%), Gaps = 29/199 (14%)
Query: 8 DAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPC--FGGRV--- 61
D P + C G RCV++ FRCE C DG + R N C + GR+
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCE-CKTGYYFDGIS-RMCVDVNECQRYPGRLCGH 413
Query: 62 PCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTG 118
C++ G Y C C GF +G C I+ C ++ C Q C YG C G
Sbjct: 414 KCENTL-GSYLCS-CSVGFRLSVDGRSCEDINECSSSPCSQ--ECANV-YGSYQCYCRRG 468
Query: 119 YV---GDGRQCQHVCDAQKPCGRE---RRCMPKSTSPYYECEGCPS-GYQW--NGYTCVD 169
Y DG C+ + + P G RC+ S ++C CPS GY+ NG C D
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS--FQCS-CPSSGYRLAPNGRNCQD 525
Query: 170 MDECDL-IRPCDDLVSCRN 187
+DEC I C +C N
Sbjct: 526 IDECVTGIHNCSINETCFN 544
>X53741-1|CAA37770.1| 566|Homo sapiens fibulin-1 A protein.
Length = 566
Score = 64.9 bits (151), Expect = 1e-09
Identities = 70/243 (28%), Positives = 102/243 (41%), Gaps = 41/243 (16%)
Query: 20 VGERCVDTDQGFRCER----CPGSQ--TSDGQTC----RTACSANPCFGGRVPCQDLPDG 69
+G C++T+ + C++ C +G C A A PC G C + P G
Sbjct: 321 IGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGH-RCVNSP-G 378
Query: 70 RYQCGKCPSGFHGNGVECYRISCRANTCFQ------GVSCEETQYGPKCGSCPTGY--VG 121
++C +C +G++ +G+ R+ N C + G CE T C SC G+
Sbjct: 379 SFRC-ECKTGYYFDGIS--RMCVDVNECQRYPGRLCGHKCENTLGSYLC-SCSVGFRLSV 434
Query: 122 DGRQCQHVCD-AQKPCGRERRCMPKSTSPYYECEGCPSGYQWN---GYTCVDMDECDLIR 177
DGR C+ + + + PC +E C S Y+C C GYQ + G TC D+DEC L
Sbjct: 435 DGRSCEDINECSSSPCSQE--CANVYGS--YQCY-CRRGYQLSDVDGVTCEDIDECAL-- 487
Query: 178 PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRL 237
P + C S G+R N R +C D+DEC G NC
Sbjct: 488 PTGGHI-C--SYRCINIPGSFQCSCPSSGYRLAPNGR---NCQDIDECVTGIHNCSINET 541
Query: 238 CVN 240
C N
Sbjct: 542 CFN 544
Score = 63.3 bits (147), Expect = 3e-09
Identities = 82/316 (25%), Positives = 125/316 (39%), Gaps = 56/316 (17%)
Query: 56 CFGG---RVPCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-C--RANTCFQGVSCEETQ 107
C GG + C+D D C C G+ +GV C ++ C +++C G SC T
Sbjct: 180 CRGGGPCKQQCRDTGD-EVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTV 237
Query: 108 YGPKC---GSCPTGY-VGDGRQCQHVCDAQKPCGRERRCMP----KSTSPYYECEG---C 156
+C SC TGY + + C+ + + + C+P ++T + C C
Sbjct: 238 GSFRCQRDSSCGTGYELTEDNSCKDIDECESGI---HNCLPDFICQNTLGSFRCRPKLQC 294
Query: 157 PSGYQWNGY-TCVDMDEC-DLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNER 214
SG+ + C+D++EC + PC +C N E RG
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCG-----RGYHLNE 349
Query: 215 RREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCF 274
CVDVDECA C +G CVN+P GS+ C G+Y+ +R C
Sbjct: 350 EGTRCVDVDECAPPAEPCGKGHRCVNSP-----------GSFRCECKTGYYFDGISRMCV 398
Query: 275 DPDSLVKRCDPSYCRRF-NAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQL-PCNE 332
D + C+R+ +C G KC G G +DG E + C+
Sbjct: 399 DVNE---------CQRYPGRLC--GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 333 PRCKKDNCPDVSNSGQ 348
C ++ C +V S Q
Sbjct: 448 SPCSQE-CANVYGSYQ 462
Score = 57.2 bits (132), Expect = 2e-07
Identities = 57/196 (29%), Positives = 86/196 (43%), Gaps = 32/196 (16%)
Query: 5 SMGDAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTAC-SANPCFGGRVP 62
S D +T C +GE C++T FRC+R T T +C + C G
Sbjct: 213 SCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHN 272
Query: 63 CQDLPD-------GRYQCG---KCPSGF----HGNGVECYRISCRANTCFQGVSCEETQY 108
C LPD G ++C +C SGF GN ++ + C G +C T+
Sbjct: 273 C--LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEG 330
Query: 109 GPKC----GSCPTGY--VGDGRQCQHVCDA---QKPCGRERRCMPKSTSPYYECEGCPSG 159
C +C GY +G +C V + +PCG+ RC+ S + CE C +G
Sbjct: 331 SYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGS--FRCE-CKTG 387
Query: 160 YQWNGYT--CVDMDEC 173
Y ++G + CVD++EC
Sbjct: 388 YYFDGISRMCVDVNEC 403
Score = 52.4 bits (120), Expect = 6e-06
Identities = 63/199 (31%), Positives = 84/199 (42%), Gaps = 29/199 (14%)
Query: 8 DAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPC--FGGRV--- 61
D P + C G RCV++ FRCE C DG + R N C + GR+
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCE-CKTGYYFDGIS-RMCVDVNECQRYPGRLCGH 413
Query: 62 PCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTG 118
C++ G Y C C GF +G C I+ C ++ C Q C YG C G
Sbjct: 414 KCENTL-GSYLCS-CSVGFRLSVDGRSCEDINECSSSPCSQ--ECANV-YGSYQCYCRRG 468
Query: 119 YV---GDGRQCQHVCDAQKPCGRE---RRCMPKSTSPYYECEGCPS-GYQW--NGYTCVD 169
Y DG C+ + + P G RC+ S ++C CPS GY+ NG C D
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS--FQCS-CPSSGYRLAPNGRNCQD 525
Query: 170 MDECDL-IRPCDDLVSCRN 187
+DEC I C +C N
Sbjct: 526 IDECVTGIHNCSINETCFN 544
>U01244-1|AAB17099.1| 703|Homo sapiens fibulin-1D protein.
Length = 703
Score = 64.9 bits (151), Expect = 1e-09
Identities = 70/243 (28%), Positives = 102/243 (41%), Gaps = 41/243 (16%)
Query: 20 VGERCVDTDQGFRCER----CPGSQ--TSDGQTC----RTACSANPCFGGRVPCQDLPDG 69
+G C++T+ + C++ C +G C A A PC G C + P G
Sbjct: 321 IGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGH-RCVNSP-G 378
Query: 70 RYQCGKCPSGFHGNGVECYRISCRANTCFQ------GVSCEETQYGPKCGSCPTGY--VG 121
++C +C +G++ +G+ R+ N C + G CE T C SC G+
Sbjct: 379 SFRC-ECKTGYYFDGIS--RMCVDVNECQRYPGRLCGHKCENTLGSYLC-SCSVGFRLSV 434
Query: 122 DGRQCQHVCD-AQKPCGRERRCMPKSTSPYYECEGCPSGYQWN---GYTCVDMDECDLIR 177
DGR C+ + + + PC +E C S Y+C C GYQ + G TC D+DEC L
Sbjct: 435 DGRSCEDINECSSSPCSQE--CANVYGS--YQCY-CRRGYQLSDVDGVTCEDIDECAL-- 487
Query: 178 PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRL 237
P + C S G+R N R +C D+DEC G NC
Sbjct: 488 PTGGHI-C--SYRCINIPGSFQCSCPSSGYRLAPNGR---NCQDIDECVTGIHNCSINET 541
Query: 238 CVN 240
C N
Sbjct: 542 CFN 544
Score = 63.3 bits (147), Expect = 3e-09
Identities = 82/316 (25%), Positives = 125/316 (39%), Gaps = 56/316 (17%)
Query: 56 CFGG---RVPCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-C--RANTCFQGVSCEETQ 107
C GG + C+D D C C G+ +GV C ++ C +++C G SC T
Sbjct: 180 CRGGGPCKQQCRDTGD-EVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTV 237
Query: 108 YGPKC---GSCPTGY-VGDGRQCQHVCDAQKPCGRERRCMP----KSTSPYYECEG---C 156
+C SC TGY + + C+ + + + C+P ++T + C C
Sbjct: 238 GSFRCQRDSSCGTGYELTEDNSCKDIDECESGI---HNCLPDFICQNTLGSFRCRPKLQC 294
Query: 157 PSGYQWNGY-TCVDMDEC-DLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNER 214
SG+ + C+D++EC + PC +C N E RG
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCG-----RGYHLNE 349
Query: 215 RREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCF 274
CVDVDECA C +G CVN+P GS+ C G+Y+ +R C
Sbjct: 350 EGTRCVDVDECAPPAEPCGKGHRCVNSP-----------GSFRCECKTGYYFDGISRMCV 398
Query: 275 DPDSLVKRCDPSYCRRF-NAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQL-PCNE 332
D + C+R+ +C G KC G G +DG E + C+
Sbjct: 399 DVNE---------CQRYPGRLC--GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 333 PRCKKDNCPDVSNSGQ 348
C ++ C +V S Q
Sbjct: 448 SPCSQE-CANVYGSYQ 462
Score = 57.2 bits (132), Expect = 2e-07
Identities = 57/196 (29%), Positives = 86/196 (43%), Gaps = 32/196 (16%)
Query: 5 SMGDAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTAC-SANPCFGGRVP 62
S D +T C +GE C++T FRC+R T T +C + C G
Sbjct: 213 SCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHN 272
Query: 63 CQDLPD-------GRYQCG---KCPSGF----HGNGVECYRISCRANTCFQGVSCEETQY 108
C LPD G ++C +C SGF GN ++ + C G +C T+
Sbjct: 273 C--LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEG 330
Query: 109 GPKC----GSCPTGY--VGDGRQCQHVCDA---QKPCGRERRCMPKSTSPYYECEGCPSG 159
C +C GY +G +C V + +PCG+ RC+ S + CE C +G
Sbjct: 331 SYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGS--FRCE-CKTG 387
Query: 160 YQWNGYT--CVDMDEC 173
Y ++G + CVD++EC
Sbjct: 388 YYFDGISRMCVDVNEC 403
Score = 52.4 bits (120), Expect = 6e-06
Identities = 63/199 (31%), Positives = 84/199 (42%), Gaps = 29/199 (14%)
Query: 8 DAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPC--FGGRV--- 61
D P + C G RCV++ FRCE C DG + R N C + GR+
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCE-CKTGYYFDGIS-RMCVDVNECQRYPGRLCGH 413
Query: 62 PCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTG 118
C++ G Y C C GF +G C I+ C ++ C Q C YG C G
Sbjct: 414 KCENTL-GSYLCS-CSVGFRLSVDGRSCEDINECSSSPCSQ--ECANV-YGSYQCYCRRG 468
Query: 119 YV---GDGRQCQHVCDAQKPCGRE---RRCMPKSTSPYYECEGCPS-GYQW--NGYTCVD 169
Y DG C+ + + P G RC+ S ++C CPS GY+ NG C D
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS--FQCS-CPSSGYRLAPNGRNCQD 525
Query: 170 MDECDL-IRPCDDLVSCRN 187
+DEC I C +C N
Sbjct: 526 IDECVTGIHNCSINETCFN 544
>AL021391-3|CAI18930.1| 703|Homo sapiens fibulin 1 protein.
Length = 703
Score = 64.9 bits (151), Expect = 1e-09
Identities = 70/243 (28%), Positives = 102/243 (41%), Gaps = 41/243 (16%)
Query: 20 VGERCVDTDQGFRCER----CPGSQ--TSDGQTC----RTACSANPCFGGRVPCQDLPDG 69
+G C++T+ + C++ C +G C A A PC G C + P G
Sbjct: 321 IGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGH-RCVNSP-G 378
Query: 70 RYQCGKCPSGFHGNGVECYRISCRANTCFQ------GVSCEETQYGPKCGSCPTGY--VG 121
++C +C +G++ +G+ R+ N C + G CE T C SC G+
Sbjct: 379 SFRC-ECKTGYYFDGIS--RMCVDVNECQRYPGRLCGHKCENTLGSYLC-SCSVGFRLSV 434
Query: 122 DGRQCQHVCD-AQKPCGRERRCMPKSTSPYYECEGCPSGYQWN---GYTCVDMDECDLIR 177
DGR C+ + + + PC +E C S Y+C C GYQ + G TC D+DEC L
Sbjct: 435 DGRSCEDINECSSSPCSQE--CANVYGS--YQCY-CRRGYQLSDVDGVTCEDIDECAL-- 487
Query: 178 PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRL 237
P + C S G+R N R +C D+DEC G NC
Sbjct: 488 PTGGHI-C--SYRCINIPGSFQCSCPSSGYRLAPNGR---NCQDIDECVTGIHNCSINET 541
Query: 238 CVN 240
C N
Sbjct: 542 CFN 544
Score = 63.3 bits (147), Expect = 3e-09
Identities = 82/316 (25%), Positives = 125/316 (39%), Gaps = 56/316 (17%)
Query: 56 CFGG---RVPCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-C--RANTCFQGVSCEETQ 107
C GG + C+D D C C G+ +GV C ++ C +++C G SC T
Sbjct: 180 CRGGGPCKQQCRDTGD-EVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTV 237
Query: 108 YGPKC---GSCPTGY-VGDGRQCQHVCDAQKPCGRERRCMP----KSTSPYYECEG---C 156
+C SC TGY + + C+ + + + C+P ++T + C C
Sbjct: 238 GSFRCQRDSSCGTGYELTEDNSCKDIDECESGI---HNCLPDFICQNTLGSFRCRPKLQC 294
Query: 157 PSGYQWNGY-TCVDMDEC-DLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNER 214
SG+ + C+D++EC + PC +C N E RG
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCG-----RGYHLNE 349
Query: 215 RREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCF 274
CVDVDECA C +G CVN+P GS+ C G+Y+ +R C
Sbjct: 350 EGTRCVDVDECAPPAEPCGKGHRCVNSP-----------GSFRCECKTGYYFDGISRMCV 398
Query: 275 DPDSLVKRCDPSYCRRF-NAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQL-PCNE 332
D + C+R+ +C G KC G G +DG E + C+
Sbjct: 399 DVNE---------CQRYPGRLC--GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 333 PRCKKDNCPDVSNSGQ 348
C ++ C +V S Q
Sbjct: 448 SPCSQE-CANVYGSYQ 462
Score = 57.2 bits (132), Expect = 2e-07
Identities = 57/196 (29%), Positives = 86/196 (43%), Gaps = 32/196 (16%)
Query: 5 SMGDAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTAC-SANPCFGGRVP 62
S D +T C +GE C++T FRC+R T T +C + C G
Sbjct: 213 SCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHN 272
Query: 63 CQDLPD-------GRYQCG---KCPSGF----HGNGVECYRISCRANTCFQGVSCEETQY 108
C LPD G ++C +C SGF GN ++ + C G +C T+
Sbjct: 273 C--LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEG 330
Query: 109 GPKC----GSCPTGY--VGDGRQCQHVCDA---QKPCGRERRCMPKSTSPYYECEGCPSG 159
C +C GY +G +C V + +PCG+ RC+ S + CE C +G
Sbjct: 331 SYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGS--FRCE-CKTG 387
Query: 160 YQWNGYT--CVDMDEC 173
Y ++G + CVD++EC
Sbjct: 388 YYFDGISRMCVDVNEC 403
Score = 52.4 bits (120), Expect = 6e-06
Identities = 63/199 (31%), Positives = 84/199 (42%), Gaps = 29/199 (14%)
Query: 8 DAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPC--FGGRV--- 61
D P + C G RCV++ FRCE C DG + R N C + GR+
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCE-CKTGYYFDGIS-RMCVDVNECQRYPGRLCGH 413
Query: 62 PCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTG 118
C++ G Y C C GF +G C I+ C ++ C Q C YG C G
Sbjct: 414 KCENTL-GSYLCS-CSVGFRLSVDGRSCEDINECSSSPCSQ--ECANV-YGSYQCYCRRG 468
Query: 119 YV---GDGRQCQHVCDAQKPCGRE---RRCMPKSTSPYYECEGCPS-GYQW--NGYTCVD 169
Y DG C+ + + P G RC+ S ++C CPS GY+ NG C D
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS--FQCS-CPSSGYRLAPNGRNCQD 525
Query: 170 MDECDL-IRPCDDLVSCRN 187
+DEC I C +C N
Sbjct: 526 IDECVTGIHNCSINETCFN 544
>AK075566-1|BAC11705.1| 638|Homo sapiens protein ( Homo sapiens
cDNA PSEC0266 fis, clone NT2RP3003649, highly similar to
Homo sapiens fibulin-1D mRNA. ).
Length = 638
Score = 64.9 bits (151), Expect = 1e-09
Identities = 70/243 (28%), Positives = 102/243 (41%), Gaps = 41/243 (16%)
Query: 20 VGERCVDTDQGFRCER----CPGSQ--TSDGQTC----RTACSANPCFGGRVPCQDLPDG 69
+G C++T+ + C++ C +G C A A PC G C + P G
Sbjct: 256 IGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGH-RCVNSP-G 313
Query: 70 RYQCGKCPSGFHGNGVECYRISCRANTCFQ------GVSCEETQYGPKCGSCPTGY--VG 121
++C +C +G++ +G+ R+ N C + G CE T C SC G+
Sbjct: 314 SFRC-ECKTGYYFDGIS--RMCVDVNECQRYPGRLCGHKCENTLGSYLC-SCSVGFRLSV 369
Query: 122 DGRQCQHVCD-AQKPCGRERRCMPKSTSPYYECEGCPSGYQWN---GYTCVDMDECDLIR 177
DGR C+ + + + PC +E C S Y+C C GYQ + G TC D+DEC L
Sbjct: 370 DGRSCEDINECSSSPCSQE--CANVYGS--YQCY-CRRGYQLSDVDGVTCEDIDECAL-- 422
Query: 178 PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRL 237
P + C S G+R N R +C D+DEC G NC
Sbjct: 423 PTGGHI-C--SYRCINIPGSFQCSCPSSGYRLAPNGR---NCQDIDECVTGIHNCSINET 476
Query: 238 CVN 240
C N
Sbjct: 477 CFN 479
Score = 63.3 bits (147), Expect = 3e-09
Identities = 82/316 (25%), Positives = 125/316 (39%), Gaps = 56/316 (17%)
Query: 56 CFGG---RVPCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-C--RANTCFQGVSCEETQ 107
C GG + C+D D C C G+ +GV C ++ C +++C G SC T
Sbjct: 115 CRGGGPCKQQCRDTGD-EVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTV 172
Query: 108 YGPKC---GSCPTGY-VGDGRQCQHVCDAQKPCGRERRCMP----KSTSPYYECEG---C 156
+C SC TGY + + C+ + + + C+P ++T + C C
Sbjct: 173 GSFRCQRDSSCGTGYELTEDNSCKDIDECESGI---HNCLPDFICQNTLGSFRCRPKLQC 229
Query: 157 PSGYQWNGY-TCVDMDEC-DLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNER 214
SG+ + C+D++EC + PC +C N E RG
Sbjct: 230 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCG-----RGYHLNE 284
Query: 215 RREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCF 274
CVDVDECA C +G CVN+P GS+ C G+Y+ +R C
Sbjct: 285 EGTRCVDVDECAPPAEPCGKGHRCVNSP-----------GSFRCECKTGYYFDGISRMCV 333
Query: 275 DPDSLVKRCDPSYCRRF-NAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQL-PCNE 332
D + C+R+ +C G KC G G +DG E + C+
Sbjct: 334 DVNE---------CQRYPGRLC--GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 382
Query: 333 PRCKKDNCPDVSNSGQ 348
C ++ C +V S Q
Sbjct: 383 SPCSQE-CANVYGSYQ 397
Score = 57.2 bits (132), Expect = 2e-07
Identities = 57/196 (29%), Positives = 86/196 (43%), Gaps = 32/196 (16%)
Query: 5 SMGDAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTAC-SANPCFGGRVP 62
S D +T C +GE C++T FRC+R T T +C + C G
Sbjct: 148 SCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHN 207
Query: 63 CQDLPD-------GRYQCG---KCPSGF----HGNGVECYRISCRANTCFQGVSCEETQY 108
C LPD G ++C +C SGF GN ++ + C G +C T+
Sbjct: 208 C--LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEG 265
Query: 109 GPKC----GSCPTGY--VGDGRQCQHVCDA---QKPCGRERRCMPKSTSPYYECEGCPSG 159
C +C GY +G +C V + +PCG+ RC+ S + CE C +G
Sbjct: 266 SYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGS--FRCE-CKTG 322
Query: 160 YQWNGYT--CVDMDEC 173
Y ++G + CVD++EC
Sbjct: 323 YYFDGISRMCVDVNEC 338
Score = 52.4 bits (120), Expect = 6e-06
Identities = 63/199 (31%), Positives = 84/199 (42%), Gaps = 29/199 (14%)
Query: 8 DAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPC--FGGRV--- 61
D P + C G RCV++ FRCE C DG + R N C + GR+
Sbjct: 291 DVDECAPPAEPCGKGHRCVNSPGSFRCE-CKTGYYFDGIS-RMCVDVNECQRYPGRLCGH 348
Query: 62 PCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTG 118
C++ G Y C C GF +G C I+ C ++ C Q C YG C G
Sbjct: 349 KCENTL-GSYLCS-CSVGFRLSVDGRSCEDINECSSSPCSQ--ECANV-YGSYQCYCRRG 403
Query: 119 YV---GDGRQCQHVCDAQKPCGRE---RRCMPKSTSPYYECEGCPS-GYQW--NGYTCVD 169
Y DG C+ + + P G RC+ S ++C CPS GY+ NG C D
Sbjct: 404 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS--FQCS-CPSSGYRLAPNGRNCQD 460
Query: 170 MDECDL-IRPCDDLVSCRN 187
+DEC I C +C N
Sbjct: 461 IDECVTGIHNCSINETCFN 479
>AF217999-1|AAG17241.1| 495|Homo sapiens unknown protein.
Length = 495
Score = 64.9 bits (151), Expect = 1e-09
Identities = 70/243 (28%), Positives = 102/243 (41%), Gaps = 41/243 (16%)
Query: 20 VGERCVDTDQGFRCER----CPGSQ--TSDGQTC----RTACSANPCFGGRVPCQDLPDG 69
+G C++T+ + C++ C +G C A A PC G C + P G
Sbjct: 191 IGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGH-RCVNSP-G 248
Query: 70 RYQCGKCPSGFHGNGVECYRISCRANTCFQ------GVSCEETQYGPKCGSCPTGY--VG 121
++C +C +G++ +G+ R+ N C + G CE T C SC G+
Sbjct: 249 SFRC-ECKTGYYFDGIS--RMCVDVNECQRYPGRLCGHKCENTLGSYLC-SCSVGFRLSV 304
Query: 122 DGRQCQHVCD-AQKPCGRERRCMPKSTSPYYECEGCPSGYQWN---GYTCVDMDECDLIR 177
DGR C+ + + + PC +E C S Y+C C GYQ + G TC D+DEC L
Sbjct: 305 DGRSCEDINECSSSPCSQE--CANVYGS--YQCY-CRRGYQLSDVDGVTCEDIDECAL-- 357
Query: 178 PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRL 237
P + C S G+R N R +C D+DEC G NC
Sbjct: 358 PTGGHI-C--SYRCINIPGSFQCSCPSSGYRLAPNGR---NCQDIDECVTGIHNCSINET 411
Query: 238 CVN 240
C N
Sbjct: 412 CFN 414
Score = 63.3 bits (147), Expect = 3e-09
Identities = 82/316 (25%), Positives = 125/316 (39%), Gaps = 56/316 (17%)
Query: 56 CFGG---RVPCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-C--RANTCFQGVSCEETQ 107
C GG + C+D D C C G+ +GV C ++ C +++C G SC T
Sbjct: 50 CRGGGPCKQQCRDTGD-EVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTV 107
Query: 108 YGPKC---GSCPTGY-VGDGRQCQHVCDAQKPCGRERRCMP----KSTSPYYECEG---C 156
+C SC TGY + + C+ + + + C+P ++T + C C
Sbjct: 108 GSFRCQRDSSCGTGYELTEDNSCKDIDECESGI---HNCLPDFICQNTLGSFRCRPKLQC 164
Query: 157 PSGYQWNGY-TCVDMDEC-DLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNER 214
SG+ + C+D++EC + PC +C N E RG
Sbjct: 165 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCG-----RGYHLNE 219
Query: 215 RREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCF 274
CVDVDECA C +G CVN+P GS+ C G+Y+ +R C
Sbjct: 220 EGTRCVDVDECAPPAEPCGKGHRCVNSP-----------GSFRCECKTGYYFDGISRMCV 268
Query: 275 DPDSLVKRCDPSYCRRF-NAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQL-PCNE 332
D + C+R+ +C G KC G G +DG E + C+
Sbjct: 269 DVNE---------CQRYPGRLC--GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 317
Query: 333 PRCKKDNCPDVSNSGQ 348
C ++ C +V S Q
Sbjct: 318 SPCSQE-CANVYGSYQ 332
Score = 57.2 bits (132), Expect = 2e-07
Identities = 57/196 (29%), Positives = 86/196 (43%), Gaps = 32/196 (16%)
Query: 5 SMGDAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTAC-SANPCFGGRVP 62
S D +T C +GE C++T FRC+R T T +C + C G
Sbjct: 83 SCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHN 142
Query: 63 CQDLPD-------GRYQCG---KCPSGF----HGNGVECYRISCRANTCFQGVSCEETQY 108
C LPD G ++C +C SGF GN ++ + C G +C T+
Sbjct: 143 C--LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEG 200
Query: 109 GPKC----GSCPTGY--VGDGRQCQHVCDA---QKPCGRERRCMPKSTSPYYECEGCPSG 159
C +C GY +G +C V + +PCG+ RC+ S + CE C +G
Sbjct: 201 SYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGS--FRCE-CKTG 257
Query: 160 YQWNGYT--CVDMDEC 173
Y ++G + CVD++EC
Sbjct: 258 YYFDGISRMCVDVNEC 273
Score = 52.4 bits (120), Expect = 6e-06
Identities = 63/199 (31%), Positives = 84/199 (42%), Gaps = 29/199 (14%)
Query: 8 DAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPC--FGGRV--- 61
D P + C G RCV++ FRCE C DG + R N C + GR+
Sbjct: 226 DVDECAPPAEPCGKGHRCVNSPGSFRCE-CKTGYYFDGIS-RMCVDVNECQRYPGRLCGH 283
Query: 62 PCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTG 118
C++ G Y C C GF +G C I+ C ++ C Q C YG C G
Sbjct: 284 KCENTL-GSYLCS-CSVGFRLSVDGRSCEDINECSSSPCSQ--ECANV-YGSYQCYCRRG 338
Query: 119 YV---GDGRQCQHVCDAQKPCGRE---RRCMPKSTSPYYECEGCPS-GYQW--NGYTCVD 169
Y DG C+ + + P G RC+ S ++C CPS GY+ NG C D
Sbjct: 339 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS--FQCS-CPSSGYRLAPNGRNCQD 395
Query: 170 MDECDL-IRPCDDLVSCRN 187
+DEC I C +C N
Sbjct: 396 IDECVTGIHNCSINETCFN 414
>AF126110-1|AAK37822.1| 703|Homo sapiens fibulin-1 isoform D
precursor protein.
Length = 703
Score = 64.9 bits (151), Expect = 1e-09
Identities = 70/243 (28%), Positives = 102/243 (41%), Gaps = 41/243 (16%)
Query: 20 VGERCVDTDQGFRCER----CPGSQ--TSDGQTC----RTACSANPCFGGRVPCQDLPDG 69
+G C++T+ + C++ C +G C A A PC G C + P G
Sbjct: 321 IGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGH-RCVNSP-G 378
Query: 70 RYQCGKCPSGFHGNGVECYRISCRANTCFQ------GVSCEETQYGPKCGSCPTGY--VG 121
++C +C +G++ +G+ R+ N C + G CE T C SC G+
Sbjct: 379 SFRC-ECKTGYYFDGIS--RMCVDVNECQRYPGRLCGHKCENTLGSYLC-SCSVGFRLSV 434
Query: 122 DGRQCQHVCD-AQKPCGRERRCMPKSTSPYYECEGCPSGYQWN---GYTCVDMDECDLIR 177
DGR C+ + + + PC +E C S Y+C C GYQ + G TC D+DEC L
Sbjct: 435 DGRSCEDINECSSSPCSQE--CANVYGS--YQCY-CRRGYQLSDVDGVTCEDIDECAL-- 487
Query: 178 PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRL 237
P + C S G+R N R +C D+DEC G NC
Sbjct: 488 PTGGHI-C--SYRCINIPGSFQCSCPSSGYRLAPNGR---NCQDIDECVTGIHNCSINET 541
Query: 238 CVN 240
C N
Sbjct: 542 CFN 544
Score = 63.3 bits (147), Expect = 3e-09
Identities = 82/316 (25%), Positives = 125/316 (39%), Gaps = 56/316 (17%)
Query: 56 CFGG---RVPCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-C--RANTCFQGVSCEETQ 107
C GG + C+D D C C G+ +GV C ++ C +++C G SC T
Sbjct: 180 CRGGGPCKQQCRDTGD-EVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTV 237
Query: 108 YGPKC---GSCPTGY-VGDGRQCQHVCDAQKPCGRERRCMP----KSTSPYYECEG---C 156
+C SC TGY + + C+ + + + C+P ++T + C C
Sbjct: 238 GSFRCQRDSSCGTGYELTEDNSCKDIDECESGI---HNCLPDFICQNTLGSFRCRPKLQC 294
Query: 157 PSGYQWNGY-TCVDMDEC-DLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNER 214
SG+ + C+D++EC + PC +C N E RG
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCG-----RGYHLNE 349
Query: 215 RREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCF 274
CVDVDECA C +G CVN+P GS+ C G+Y+ +R C
Sbjct: 350 EGTRCVDVDECAPPAEPCGKGHRCVNSP-----------GSFRCECKTGYYFDGISRMCV 398
Query: 275 DPDSLVKRCDPSYCRRF-NAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQL-PCNE 332
D + C+R+ +C G KC G G +DG E + C+
Sbjct: 399 DVNE---------CQRYPGRLC--GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 333 PRCKKDNCPDVSNSGQ 348
C ++ C +V S Q
Sbjct: 448 SPCSQE-CANVYGSYQ 462
Score = 57.2 bits (132), Expect = 2e-07
Identities = 57/196 (29%), Positives = 86/196 (43%), Gaps = 32/196 (16%)
Query: 5 SMGDAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTAC-SANPCFGGRVP 62
S D +T C +GE C++T FRC+R T T +C + C G
Sbjct: 213 SCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHN 272
Query: 63 CQDLPD-------GRYQCG---KCPSGF----HGNGVECYRISCRANTCFQGVSCEETQY 108
C LPD G ++C +C SGF GN ++ + C G +C T+
Sbjct: 273 C--LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEG 330
Query: 109 GPKC----GSCPTGY--VGDGRQCQHVCDA---QKPCGRERRCMPKSTSPYYECEGCPSG 159
C +C GY +G +C V + +PCG+ RC+ S + CE C +G
Sbjct: 331 SYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGS--FRCE-CKTG 387
Query: 160 YQWNGYT--CVDMDEC 173
Y ++G + CVD++EC
Sbjct: 388 YYFDGISRMCVDVNEC 403
Score = 52.4 bits (120), Expect = 6e-06
Identities = 63/199 (31%), Positives = 84/199 (42%), Gaps = 29/199 (14%)
Query: 8 DAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPC--FGGRV--- 61
D P + C G RCV++ FRCE C DG + R N C + GR+
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCE-CKTGYYFDGIS-RMCVDVNECQRYPGRLCGH 413
Query: 62 PCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTG 118
C++ G Y C C GF +G C I+ C ++ C Q C YG C G
Sbjct: 414 KCENTL-GSYLCS-CSVGFRLSVDGRSCEDINECSSSPCSQ--ECANV-YGSYQCYCRRG 468
Query: 119 YV---GDGRQCQHVCDAQKPCGRE---RRCMPKSTSPYYECEGCPS-GYQW--NGYTCVD 169
Y DG C+ + + P G RC+ S ++C CPS GY+ NG C D
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS--FQCS-CPSSGYRLAPNGRNCQD 525
Query: 170 MDECDL-IRPCDDLVSCRN 187
+DEC I C +C N
Sbjct: 526 IDECVTGIHNCSINETCFN 544
>AB208840-1|BAD92077.1| 830|Homo sapiens fibrillin 1 variant
protein.
Length = 830
Score = 64.5 bits (150), Expect = 1e-09
Identities = 56/167 (33%), Positives = 75/167 (44%), Gaps = 18/167 (10%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTC--RTACS-ANPCFGGRVPCQDLPDGRYQCG 74
+C +C++TD +RCE CP G C CS NPC G C+++ G ++C
Sbjct: 571 VCKHGQCINTDGSYRCE-CPFGYILAGNECVDTDECSVGNPC--GNGTCKNVIGG-FEC- 625
Query: 75 KCPSGFH-GNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQC--QH 128
C GF G + C I+ C N C T YG CP GYV D R C +
Sbjct: 626 TCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNT-YGSYECKCPVGYVLREDRRMCKDED 684
Query: 129 VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDEC 173
C+ K E++ K+ Y C C GYQ +G CVD +EC
Sbjct: 685 ECEEGKHDCTEKQMECKNLIGTYMCI-CGPGYQRRPDGEGCVDENEC 730
Score = 55.6 bits (128), Expect = 7e-07
Identities = 67/234 (28%), Positives = 89/234 (38%), Gaps = 31/234 (13%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQT-CR--TACSANPCFGGRVPCQDLPDGRYQCG 74
+C +C+DT F C G +T+D QT C C + C G C++ G + C
Sbjct: 294 ICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGT--CRNTI-GSFNC- 349
Query: 75 KCPSGF---HGNGV----ECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQ 125
+C GF H N EC S N C G C T +C C GY DGR
Sbjct: 350 RCNHGFILSHNNDCIDVDEC--ASGNGNLCRNG-QCINTVGSFQC-QCNEGYEVAPDGRT 405
Query: 126 CQHVCDAQKPCGRERRCMP---KSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDL 182
C D + R+C P ++ Y C CP GY C D+DEC L
Sbjct: 406 C---VDINECLLEPRKCAPGTCQNLDGSYRCI-CPPGYSLQNEKCEDIDECVEEPEICAL 461
Query: 183 VSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGR 236
+C N E S G R + R +C E G+ + P+ R
Sbjct: 462 GTCSNTEGSFKCLCPEGFSLSSSGRR--CQDLRMSYCYAKFE--GGKCSSPKSR 511
Score = 54.0 bits (124), Expect = 2e-06
Identities = 65/230 (28%), Positives = 95/230 (41%), Gaps = 33/230 (14%)
Query: 24 CVDTDQGFRCERCPGSQ-TSDGQ-TCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
C++T +RC+ PG + TS GQ R C P C D G + C C +GF
Sbjct: 259 CINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTV-GSFYC-LCHTGFK 316
Query: 82 GNGVE--CYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGYV-GDGRQCQHVCDAQKPCG 137
N + C I+ C + C G +C T C C G++ C V + G
Sbjct: 317 TNDDQTMCLDINECERDACGNG-TCRNTIGSFNC-RCNHGFILSHNNDCIDVDECASGNG 374
Query: 138 ---RERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDL-IRPCDDLVSCRNEEXX 191
R +C+ +T ++C+ C GY+ +G TCVD++EC L R C +C+N +
Sbjct: 375 NLCRNGQCI--NTVGSFQCQ-CNEGYEVAPDGRTCVDINECLLEPRKCAP-GTCQNLDGS 430
Query: 192 XXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNT 241
G + E C D+DEC + C G C NT
Sbjct: 431 YRCIC------------PPGYSLQNEKCEDIDECVEEPEICALG-TCSNT 467
Score = 51.2 bits (117), Expect = 1e-05
Identities = 69/282 (24%), Positives = 108/282 (38%), Gaps = 54/282 (19%)
Query: 69 GRYQCGKCPSGFHGNG--VECYRIS-CRAN-TCFQGVSCEETQYGPKCGSCP------TG 118
G ++C +CP GF N + C I C+ C + C T +C P TG
Sbjct: 222 GSFRC-ECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTG 280
Query: 119 YVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLI 176
D +CQ + + C + C+ S Y C +G++ N C+D++EC+
Sbjct: 281 QCNDRNECQEIPNI---CSHGQ-CIDTVGSFYCLCH---TGFKTNDDQTMCLDINECE-- 331
Query: 177 RPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGR 236
R +CRN + G+ + N C+DVDECA G N R
Sbjct: 332 RDACGNGTCRN-------TIGSFNCRCNHGFILSHNN----DCIDVDECASGNGNLCRNG 380
Query: 237 LCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLV---KRCDPSYCRRFNA 293
C+NT GS+ C G+ R C D + + ++C P C+ +
Sbjct: 381 QCINT-----------VGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDG 429
Query: 294 VCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRC 335
+C+C G++ C D+D +E C C
Sbjct: 430 ----SYRCICPPGYSLQNEKC---EDIDECVEEPEICALGTC 464
Score = 43.6 bits (98), Expect = 0.003
Identities = 57/222 (25%), Positives = 81/222 (36%), Gaps = 37/222 (16%)
Query: 95 NTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKPCGRERRCMPKSTSPYYE 152
+ C G C T +C CP GY+ G +C C PCG C K+ +E
Sbjct: 570 DVCKHG-QCINTDGSYRC-ECPFGYILAGNECVDTDECSVGNPCGNGT-C--KNVIGGFE 624
Query: 153 CEGCPSGYQWNGY-TCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTG 211
C C G++ TC D++EC P C N G
Sbjct: 625 CT-CEEGFEPGPMMTCEDINECAQ-NPLLCAFRCVNTYGSYECKCPV----------GYV 672
Query: 212 NERRREHCVDVDECADGRANCPRGRL-CVNTPQYPSNPVSSLQGSYICVPCG-GHYYVNT 269
R C D DEC +G+ +C ++ C N L G+Y+C+ CG G+
Sbjct: 673 LREDRRMCKDEDECEEGKHDCTEKQMECKN-----------LIGTYMCI-CGPGYQRRPD 720
Query: 270 TRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCNTGWTGN 310
C D + + P C + G C CN G+T +
Sbjct: 721 GEGCVDENEC--QTKPGICENGRCLNTRGSYTCECNDGFTAS 760
Score = 43.2 bits (97), Expect = 0.004
Identities = 52/192 (27%), Positives = 79/192 (41%), Gaps = 33/192 (17%)
Query: 8 DAGSMVTPFKLCVGERCVDTDQGFRCERCPG--SQTSDGQTCRTACSANPCFGGRVPCQD 65
D V ++C C +T+ F+C CP S +S G+ C+ + C+
Sbjct: 448 DIDECVEEPEICALGTCSNTEGSFKC-LCPEGFSLSSSGRRCQDL-RMSYCYA------- 498
Query: 66 LPDGRYQCGKC--PSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGS---CPTG-- 118
+++ GKC P + + EC C G CE P CP G
Sbjct: 499 ----KFEGGKCSSPKSRNHSKQEC---CCALKGEGWGDPCELCPTEPDEAFRQICPYGSG 551
Query: 119 -YVGDGRQCQHVCDAQKP--CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDL 175
VG + + ++P C + +C+ +T Y CE CP GY G CVD DEC +
Sbjct: 552 IIVGPDDSAVDMDECKEPDVC-KHGQCI--NTDGSYRCE-CPFGYILAGNECVDTDECSV 607
Query: 176 IRPCDDLVSCRN 187
PC + +C+N
Sbjct: 608 GNPCGN-GTCKN 618
Score = 41.5 bits (93), Expect = 0.011
Identities = 86/335 (25%), Positives = 123/335 (36%), Gaps = 60/335 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPC----FGGRVPCQDLPDGRYQC 73
LC G +C++T F+C RCP + T R N C G C + G Y C
Sbjct: 51 LCQGGKCINTFGSFQC-RCPTGYYLNEDT-RVCDDVNECETPGICGPGTCYNTV-GNYTC 107
Query: 74 GKCPSGFHGNG----VECYRISCRANTCFQGVSCE-ETQYGPKCGSCPTGYVGDGRQCQH 128
P NG ++ R C N +C+ E + C Y GR
Sbjct: 108 ICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSY-NIGRAWN- 165
Query: 129 VCDAQKPCGRERRCMPKSTSPYYE-CEGCPSGYQWNGYTC--VDMDEC-DLIRPCDDLVS 184
KPC +C ST + C G+ + YT VD+DEC ++ C++ V
Sbjct: 166 -----KPC---EQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGV- 216
Query: 185 CRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQY 244
C N + G + C D+DEC +G C R C+NT
Sbjct: 217 CIN----------MVGSFRCECPVGFFYNDKLLVCEDIDECQNGPV-CQRNAECINT--- 262
Query: 245 PSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVC 303
GSY C C Y +T C D + + P+ C + G C+C
Sbjct: 263 --------AGSYRC-DCKPGYRFTSTGQCNDRNECQE--IPNICSHGQCIDTVGSFYCLC 311
Query: 304 NTGWTGNG--TVCGLDRDLDGHPDEQLPCNEPRCK 336
+TG+ N T+C LD + E+ C C+
Sbjct: 312 HTGFKTNDDQTMC-----LDINECERDACGNGTCR 341
>X62009-1|CAB56757.1| 754|Homo sapiens fibrillin 5 protein.
Length = 754
Score = 64.1 bits (149), Expect = 2e-09
Identities = 87/336 (25%), Positives = 129/336 (38%), Gaps = 56/336 (16%)
Query: 18 LCVGERCVDTDQGFRCERCP-GSQTSDG-QTC----RTACSANPCFGGRVPCQDLPDGRY 71
LC G CV+T+ F+C+ CP G + S + C + S N C G+ C ++ G Y
Sbjct: 416 LCRGGTCVNTEGSFQCD-CPLGHELSPSREDCVDINECSLSDNLCRNGK--CVNM-IGTY 471
Query: 72 QCGKCPSGFHG--NGVECYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGRQC 126
QC C G+ + C I C C ++ +C SC GY + DGR C
Sbjct: 472 QC-SCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYEC-SCSEGYALMPDGRSC 529
Query: 127 QHV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLIRPCDDL 182
+ C+ +C + Y C C G+ + TC+D++ECDL
Sbjct: 530 ADIDECENNPDICDGGQC--TNIPGEYRCL-CYDGFMASMDMKTCIDVNECDLNSNICMF 586
Query: 183 VSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
C N + G ++ C DVDEC G NC C+N P
Sbjct: 587 GECENTKGSFICHCQL----------GYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIP 636
Query: 243 QYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQ 299
GS+ C C + N + C D D + ++ NA C
Sbjct: 637 -----------GSFKC-SCREGWIGNGIK-CIDRDEC---SNGTHQCSINAQCVNTPGSY 680
Query: 300 KCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRC 335
+C C+ G+TG+G C D+D + C +C
Sbjct: 681 RCACSEGFTGDGFTCS---DVDECAENINLCENGQC 713
Score = 62.1 bits (144), Expect = 8e-09
Identities = 84/307 (27%), Positives = 113/307 (36%), Gaps = 51/307 (16%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQ-TSDGQTCRTACSANPCFGG-RVPCQDLPDGRYQCGK 75
LC +CV+ ++C PG Q T D Q C GG C + +G Y+C
Sbjct: 458 LCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTN-SEGSYECS- 515
Query: 76 CPSGFH--GNGVECYRIS-CRANTCF-QGVSCEETQYGPKCGSCPTGYVG--DGRQCQHV 129
C G+ +G C I C N G C +C C G++ D + C V
Sbjct: 516 CSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRC-LCYDGFMASMDMKTCIDV 574
Query: 130 --CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYT--CVDMDECDL-IRPCDDLVS 184
CD C ++T + C C GY T C D+DEC++ CD S
Sbjct: 575 NECDLNSNICMFGEC--ENTKGSFICH-CQLGYSVKKGTTGCTDVDECEIGAHNCDMHAS 631
Query: 185 CRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQY 244
C N +GW G G + C+D DEC++G C CVNTP
Sbjct: 632 CLN-------IPGSFKCSCREGWIGNGIK-----CIDRDECSNGTHQCSINAQCVNTP-- 677
Query: 245 PSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSL---VKRCDPSYCRRFNAVCGFGQKC 301
GSY C G + C D D + C+ C V G +C
Sbjct: 678 ---------GSYRCACSEG--FTGDGFTCSDVDECAENINLCENGQCLN---VPG-AYRC 722
Query: 302 VCNTGWT 308
C G+T
Sbjct: 723 ECEMGFT 729
Score = 60.5 bits (140), Expect = 2e-08
Identities = 90/321 (28%), Positives = 118/321 (36%), Gaps = 54/321 (16%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTS--DGQTCR--TACSANP--CFGGRVPCQDLPDGRY 71
LC CV+T F CE G ++ + C C NP C GG C + +G +
Sbjct: 373 LCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGG--TCVN-TEGSF 429
Query: 72 QCGKCPSGF-----HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGY--VGDGR 124
QC CP G + V+ S N C G C +C SC GY D +
Sbjct: 430 QC-DCPLGHELSPSREDCVDINECSLSDNLCRNG-KCVNMIGTYQC-SCNPGYQATPDRQ 486
Query: 125 QCQHVCDAQ-KPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDD 181
C + + G + +C S YEC C GY +G +C D+DEC+ D
Sbjct: 487 GCTDIDECMIMNGGCDTQCTNSEGS--YEC-SCSEGYALMPDGRSCADIDECENNPDICD 543
Query: 182 LVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNT 241
C N + G + C+DV+EC C G C NT
Sbjct: 544 GGQCTN----------IPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGE-CENT 592
Query: 242 PQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSL---VKRCDPSYCRRFNAVCGFG 298
+GS+IC G+ T C D D CD + N F
Sbjct: 593 -----------KGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCD-MHASCLNIPGSF- 639
Query: 299 QKCVCNTGWTGNGTVCGLDRD 319
KC C GW GNG C +DRD
Sbjct: 640 -KCSCREGWIGNGIKC-IDRD 658
Score = 39.9 bits (89), Expect = 0.035
Identities = 29/98 (29%), Positives = 40/98 (40%), Gaps = 15/98 (15%)
Query: 218 HCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPD 277
+C+D+DEC R C G LC NTP GSY C G+ + T C D +
Sbjct: 55 NCIDIDECLVNRLLCDNG-LCRNTP-----------GSYSCTCPPGYVFRTETETCEDIN 102
Query: 278 SLVKR-CDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
C CR N + F +C + + G +C
Sbjct: 103 ECESNPCVNGACR--NNLGSFNCECSPGSKLSSTGLIC 138
Score = 31.9 bits (69), Expect = 9.2
Identities = 17/39 (43%), Positives = 22/39 (56%), Gaps = 3/39 (7%)
Query: 151 YECEGCPSGYQ--WNGYTCVDMDECDLIRPCDDLVSCRN 187
Y C C SGY+ +G C+D+DEC + R D CRN
Sbjct: 39 YRCN-CNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRN 76
>BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein.
Length = 1235
Score = 63.7 bits (148), Expect = 2e-09
Identities = 50/167 (29%), Positives = 66/167 (39%), Gaps = 13/167 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C+D F C PG QT C + PC G C D + Y C KC +GF
Sbjct: 923 GGSCMDGVNTFSCLCLPGFTGDKYQTDMNECLSEPCKNGGT-CSDYVNS-YTC-KCQAGF 979
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C ++CF G +C + C CP G+ G C H + + PC
Sbjct: 980 DGVHCENNINECTESSCFNGGTCVDGINSFSC-LCPVGFTGS--FCLHEINECSSHPCLN 1036
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSC 185
E C+ + Y C CP GY G C + PC + +C
Sbjct: 1037 EGTCVDGLGT--YRC-SCPLGY--TGKNCQTLVNLCSRSPCKNKGTC 1078
Score = 61.3 bits (142), Expect = 1e-08
Identities = 52/171 (30%), Positives = 72/171 (42%), Gaps = 14/171 (8%)
Query: 19 CVGE-RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCP 77
C+ + RC+D G++C PG+ + + C++NPC G C D RY C C
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHG--ICMD-GINRYSC-VCS 671
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCG 137
GF G C +N C +G +C G +C CP G Q PC
Sbjct: 672 PGFTGQRCNIDIDECASNPCRKGATCINGVNGFRC-ICPEGPHHPSCYSQVNECLSNPC- 729
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C + Y+C C +G W G C VD +EC L PC + +C N
Sbjct: 730 IHGNCTGGLSG--YKCL-CDAG--WVGINCEVDKNEC-LSNPCQNGGTCDN 774
Score = 60.5 bits (140), Expect = 2e-08
Identities = 74/303 (24%), Positives = 105/303 (34%), Gaps = 34/303 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C D G+ C + QT CS NPC V C++ P+ C G+ G
Sbjct: 810 CFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAV-CKESPNFESYTCLCAPGWQGQ 868
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
C + C C TQ C CP G+ G C+ D PC
Sbjct: 869 RCTIDIDECISKPCMNHGLCHNTQGSYMC-ECPPGF--SGMDCEEDIDDCLANPCQNGGS 925
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXX 201
CM + + C C G+ + Y DM+EC L PC + +C +
Sbjct: 926 CMDGVNT--FSCL-CLPGFTGDKYQ-TDMNEC-LSEPCKNGGTC--SDYVNSYTCKCQAG 978
Query: 202 XXSQGWRGTGNERRREHCVDVDECADGRAN----CP---RGRLCVNTPQYPSNPVSSLQG 254
NE C + C DG + CP G C++ S+ +G
Sbjct: 979 FDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEG 1038
Query: 255 SYICVPCGGHYYVN-----TTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQKCVCNTG 306
+ CV G Y + T + C +LV C S C+ C +C+C +G
Sbjct: 1039 T--CVDGLGTYRCSCPLGYTGKNC---QTLVNLCSRSPCKN-KGTCVQKKAESQCLCPSG 1092
Query: 307 WTG 309
W G
Sbjct: 1093 WAG 1095
Score = 60.1 bits (139), Expect = 3e-08
Identities = 79/295 (26%), Positives = 111/295 (37%), Gaps = 49/295 (16%)
Query: 21 GERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C++ GFRC CP G + C +NPC G C G Y+C C +G
Sbjct: 694 GATCINGVNGFRCI-CPEGPHHPSCYSQVNECLSNPCIHGN--CTGGLSG-YKC-LCDAG 748
Query: 80 FHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCG 137
+ G E + C +N C G +C+ G +C +C G+ G CQ D A PC
Sbjct: 749 WVGINCEVDKNECLSNPCQNGGTCDNLVNGYRC-TCKKGF--KGYNCQVNIDECASNPCL 805
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXX 197
+ C + Y C C Y G C + PC++ C+
Sbjct: 806 NQGTCFDDISG--YTCH-CVLPY--TGKNCQTVLAPCSPNPCENAAVCKESP-----NFE 855
Query: 198 XXXXXXSQGWRGTGNERRREHC-VDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSY 256
+ GW+G + C +D+DEC C LC NT QGSY
Sbjct: 856 SYTCLCAPGWQG-------QRCTIDIDECIS--KPCMNHGLCHNT-----------QGSY 895
Query: 257 ICVPCGGHYYVNTTRPCFDPDSLVKRC-DPSYCRRFNAVCGFGQKCVCNTGWTGN 310
+C C + D D L C + C + V F C+C G+TG+
Sbjct: 896 MC-ECPPGFSGMDCEEDID-DCLANPCQNGGSC--MDGVNTF--SCLCLPGFTGD 944
Score = 59.3 bits (137), Expect = 5e-08
Identities = 62/228 (27%), Positives = 91/228 (39%), Gaps = 36/228 (15%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSA-NPCFGGRVPCQDLPDGRYQCGKCPSG 79
G C F C+ G +T C C G C +LP G YQC +CP G
Sbjct: 156 GSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGT-CLNLP-GSYQC-QCPQG 212
Query: 80 FHGNGVECYRISCRANTCFQGVSCEET-QYGPKCGSCPTGYVGDGRQCQHVCD--AQKPC 136
F G + + C + C G +C +T + +C +C G+ +G C+ D C
Sbjct: 213 FTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFEC-NCLPGF--EGSTCERNIDDCPNHRC 269
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRP--CDDLVSCRNEEXXXX 193
C+ + Y C CP QW G C D+DEC L++P C + +C N
Sbjct: 270 QNGGVCVDGVNT--YNCR-CPP--QWTGQFCTEDVDEC-LLQPNACQNGGTCANRNGGYG 323
Query: 194 XXXXXXXXXXSQGWRGTGNERRREHCVD-VDECADGRANCPRGRLCVN 240
GW G + C + +D+CA A+C G C++
Sbjct: 324 CVCV-------NGWSG-------DDCSENIDDCA--FASCTPGSTCID 355
Score = 58.4 bits (135), Expect = 9e-08
Identities = 81/312 (25%), Positives = 112/312 (35%), Gaps = 39/312 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C+D GF C PG + + C +NPC C D + R+QC CP GF G
Sbjct: 471 CLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNG-QCVDKVN-RFQC-LCPPGFTGP 527
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
+ C + C G C + G +C C TG+ G C+ D PC +
Sbjct: 528 VCQIDIDDCSSTPCLNGAKCIDHPNGYEC-QCATGFT--GVLCEENIDNCDPDPC-HHGQ 583
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRP------CDDLV-----SCRNEE 189
C S Y C C GY G C D +DEC P C DLV +C+
Sbjct: 584 CQDGIDS--YTCI-CNPGYM--GAICSDQIDEC-YSSPCLNDGRCIDLVNGYQCNCQPGT 637
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNER-RREHCVDVDECADGRANCPRGRLCVNTPQYPSNP 248
+ G + R CV R N N + +
Sbjct: 638 SGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATC 697
Query: 249 VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGF-GQKCVCNTGW 307
++ + G P G H+ C+ S V C + C N G G KC+C+ GW
Sbjct: 698 INGVNGFRCICPEGPHH-----PSCY---SQVNECLSNPCIHGNCTGGLSGYKCLCDAGW 749
Query: 308 TGNGTVCGLDRD 319
G C +D++
Sbjct: 750 VGIN--CEVDKN 759
Score = 51.6 bits (118), Expect = 1e-05
Identities = 44/158 (27%), Positives = 66/158 (41%), Gaps = 14/158 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D + C+ G + C+ + CF G C D + + C CP GF
Sbjct: 961 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGT-CVDGINS-FSC-LCPVGF 1017
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G+ C ++ C +C + +C SCP GY G+ CQ + + ++ PC
Sbjct: 1018 TGSFCLHEINECSSHPCLNEGTCVDGLGTYRC-SCPLGYT--GKNCQTLVNLCSRSPCKN 1074
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDL 175
+ C+ K +C CPSG W G C V CD+
Sbjct: 1075 KGTCVQKKAES--QCL-CPSG--WAGAYCDVPNVSCDI 1107
Score = 50.4 bits (115), Expect = 2e-05
Identities = 52/181 (28%), Positives = 73/181 (40%), Gaps = 26/181 (14%)
Query: 16 FKLCV-GERCVDTDQGFRCERCPGSQTSDGQTCRT--ACSANPCFGGRVPCQDLP-DGRY 71
F C G C+D F C CP + G C AC +NPC G + C P +G+Y
Sbjct: 344 FASCTPGSTCIDRVASFSC-MCPEGKA--GLLCHLDDACISNPCHKGAL-CDTNPLNGQY 399
Query: 72 QCGKCPSGFHGNGV-----ECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQC 126
C CP G+ G EC +N C C T C C GY G +
Sbjct: 400 IC-TCPQGYKGADCTEDVDEC--AMANSNPCEHAGKCVNTDGAFHC-ECLKGYAGPRCEM 455
Query: 127 Q-HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVS 184
+ C + PC + C+ K + C C G++ G C ++++EC PC +
Sbjct: 456 DINECHSD-PCQNDATCLDKIGG--FTCL-CMPGFK--GVHCELEINECQ-SNPCVNNGQ 508
Query: 185 C 185
C
Sbjct: 509 C 509
Score = 48.0 bits (109), Expect = 1e-04
Identities = 46/168 (27%), Positives = 64/168 (38%), Gaps = 13/168 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G +C+D G+ C+ G + C +PC G+ CQD D Y C C G+
Sbjct: 544 GAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQ--CQDGIDS-YTC-ICNPGY 599
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
G C ++ C C + G +C +C G G + A PC
Sbjct: 600 MGAICSDQIDECYSSPCLNDGRCIDLVNGYQC-NCQPGTSGVNCEINFDDCASNPC-IHG 657
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
CM Y C C G+ G C +D+DEC PC +C N
Sbjct: 658 ICMDGINR--YSCV-CSPGF--TGQRCNIDIDEC-ASNPCRKGATCIN 699
Score = 48.0 bits (109), Expect = 1e-04
Identities = 52/176 (29%), Positives = 69/176 (39%), Gaps = 28/176 (15%)
Query: 19 CVGE-RCVDTDQGFRCERCPGSQTSDG-QTCRTACSANPCFGGRVPCQDLPDGRYQCGKC 76
C+ E CVD +RC CP T QT CS +PC Q + QC C
Sbjct: 1034 CLNEGTCVDGLGTYRCS-CPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAES--QC-LC 1089
Query: 77 PSGFHGNGVECYRISCRANTCFQGVSCEET-QYGPKC---GS-----CPTGYVGD----- 122
PSG+ G + +SC +GV E Q+ C G+ CP GY G
Sbjct: 1090 PSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQ 1149
Query: 123 -----GRQCQHVCDAQKPCGRER-RCMP--KSTSPYYECEGCPSGYQWNGYTCVDM 170
CQH G R C+P + + YE + C + NG TC+D+
Sbjct: 1150 LDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDL 1205
Score = 40.7 bits (91), Expect = 0.020
Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 8/87 (9%)
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--A 132
+CP G+ G+ E C +N C G +C + G +C C GY G C++ D
Sbjct: 1136 QCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRC-ECVPGY--QGVNCEYEVDECQ 1192
Query: 133 QKPCGRERRCMPKSTSPYYECEGCPSG 159
+PC C+ +++C CP G
Sbjct: 1193 NQPCQNGGTCI--DLVNHFKC-SCPPG 1216
Score = 35.9 bits (79), Expect = 0.57
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D G+RCE PG Q + + C PC G C DL + ++C CP G
Sbjct: 1161 GATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGT-CIDLVN-HFKC-SCPPGT 1217
Query: 81 HG 82
G
Sbjct: 1218 RG 1219
>AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive
sequence DNA binding protein-1 protein.
Length = 1008
Score = 63.7 bits (148), Expect = 2e-09
Identities = 46/142 (32%), Positives = 63/142 (44%), Gaps = 11/142 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D G+ C G + + + R C A+PC G C++LP G Y C +CP+GF
Sbjct: 380 GGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGG-SCRNLP-GAYVC-RCPAGF 436
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA--QKPCGR 138
G E +C ++ C G CE C CP G+ G C+ V D PCG
Sbjct: 437 VGVHCETEVDACDSSPCQHGGRCESGGGAYLC-VCPEGFF--GYHCETVSDPCFSSPCGG 493
Query: 139 ERRCMPKSTSPYYECEGCPSGY 160
C+ + S + C C GY
Sbjct: 494 RGYCLASNGS--HSCT-CKVGY 512
Score = 62.1 bits (144), Expect = 8e-09
Identities = 45/130 (34%), Positives = 57/130 (43%), Gaps = 11/130 (8%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGP 110
C + PC G CQD G Y C C +G+ G E R CRA+ C G SC
Sbjct: 372 CRSQPCLHGG-SCQDRVAG-YLC-LCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAY 428
Query: 111 KCGSCPTGYVGDGRQCQ-HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD 169
C CP G+VG + + CD+ PC RC +S Y C CP G+ GY C
Sbjct: 429 VC-RCPAGFVGVHCETEVDACDS-SPCQHGGRC--ESGGGAYLCV-CPEGF--FGYHCET 481
Query: 170 MDECDLIRPC 179
+ + PC
Sbjct: 482 VSDPCFSSPC 491
Score = 54.0 bits (124), Expect = 2e-06
Identities = 46/144 (31%), Positives = 62/144 (43%), Gaps = 17/144 (11%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYG 109
C+++PCF G C D D Y C +CP GFHG E R C + C G +C+E
Sbjct: 160 CNSDPCFNGG-SC-DAHDDSYTC-ECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGE 216
Query: 110 PKCGSCPTGYVGDGRQCQ----HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGY 165
C SCP Y GR C+ C A PC C Y+C+ CP G+ +G
Sbjct: 217 YHC-SCP--YRFTGRHCEIGKPDSC-ASGPCHNGGTCFHYIGK--YKCD-CPPGF--SGR 267
Query: 166 TCVDMDECDLIRPCDDLVSCRNEE 189
C PC + +C + +
Sbjct: 268 YCEIAPSPCFRSPCVNGGTCEDRD 291
Score = 50.8 bits (116), Expect = 2e-05
Identities = 81/334 (24%), Positives = 119/334 (35%), Gaps = 71/334 (21%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRT----ACSANPCFGGRVPCQDLPDGRYQCGKC 76
G C + + C CP T G+ C +C++ PC G + G+Y+C C
Sbjct: 207 GGTCKEAGGEYHCS-CPYRFT--GRHCEIGKPDSCASGPCHNGGTCFHYI--GKYKCD-C 260
Query: 77 PSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPC 136
P GF G E C + C G +CE+ C C GY+ GR+CQ D P
Sbjct: 261 PPGFSGRYCEIAPSPCFRSPCVNGGTCEDRDTDFFC-HCQAGYM--GRRCQAEVDCGPPE 317
Query: 137 GRERRCM-----PKSTSPYYECEG------------C-PSGYQWNGYTCVDMDECDLIRP 178
+ + + Y C+ C P G C+++DEC +P
Sbjct: 318 EVKHATLRFNGTRLGAAALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDEC-RSQP 376
Query: 179 CDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRA-------- 230
C SC++ S G+ G E R+ C C +G +
Sbjct: 377 CLHGGSCQDR-------VAGYLCLCSTGYEGAHCELERDEC-RAHPCRNGGSCRNLPGAY 428
Query: 231 --NCPRGRL----------CVNTPQYPSNPVSSLQGSYICV-PCG--GHYYVNTTRPCFD 275
CP G + C ++P S G+Y+CV P G G++ + PCF
Sbjct: 429 VCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPEGFFGYHCETVSDPCFS 488
Query: 276 PDSLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTG 309
+ YC N C C G+TG
Sbjct: 489 SPCGGR----GYCLASNG----SHSCTCKVGYTG 514
Score = 38.3 bits (85), Expect = 0.11
Identities = 55/204 (26%), Positives = 73/204 (35%), Gaps = 49/204 (24%)
Query: 21 GERCVDTDQGFRCERCP--------GSQTSDGQTCR----------TACSANPCFGG--- 59
G CVD DQG+ CE CP + D CR T C F G
Sbjct: 56 GGTCVDADQGYVCE-CPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLC 114
Query: 60 -----RVPCQ---DLPDGRY--QCG---KCPSGFHGNGVECYRISCRANTCFQGVSCEET 106
+PC PDG Y + G C N C ++ CF G SC+
Sbjct: 115 EFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCNSDPCFNGGSCDAH 174
Query: 107 QYGPKCGSCPTGYVGDGRQCQ----HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW 162
C CP G+ G+ C+ H+C + PC C K Y C CP Y++
Sbjct: 175 DDSYTC-ECPRGF--HGKHCEKARPHLC-SSGPCRNGGTC--KEAGGEYHC-SCP--YRF 225
Query: 163 NGYTC-VDMDECDLIRPCDDLVSC 185
G C + + PC + +C
Sbjct: 226 TGRHCEIGKPDSCASGPCHNGGTC 249
>AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant
protein.
Length = 1289
Score = 63.7 bits (148), Expect = 2e-09
Identities = 56/167 (33%), Positives = 72/167 (43%), Gaps = 21/167 (12%)
Query: 19 CV-GERCVDTDQGFRCERCPGSQTSDGQTCR---TACSANPCFGGRVPCQDLPDGRYQCG 74
CV G C D GF C CP G TC+ C++ PC G C D PDG Y+C
Sbjct: 481 CVNGGVCKDRVNGFSC-TCPSG--FSGSTCQLDVDECASTPCRNG-AKCVDQPDG-YEC- 534
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQ 133
+C GF G + C + C G C + C +C GY G + Q C +Q
Sbjct: 535 RCAEGFEGTLCDRNVDDCSPDPCHHG-RCVDGIASFSC-ACAPGYTGTRCESQVDECRSQ 592
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPC 179
PC +C+ Y C CPSG G C V++D+C PC
Sbjct: 593 -PCRHGGKCL--DLVDKYLCR-CPSG--TTGVNCEVNIDDC-ASNPC 632
Score = 61.3 bits (142), Expect = 1e-08
Identities = 50/155 (32%), Positives = 64/155 (41%), Gaps = 15/155 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G CVD + GFRC PGS C+ PC G C D P G ++C C G+
Sbjct: 672 GGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHG--ICYDAPGG-FRC-VCEPGW 727
Query: 81 HGN--GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD-AQKPCG 137
G R +C + C G +C G C +CP G GRQC+ + PC
Sbjct: 728 SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHC-TCPPGV--QGRQCELLSPCTPNPCE 784
Query: 138 RERRCMPKSTSPYYECEGCPSGYQ---WNGYTCVD 169
RC +S CP G+Q NG +C D
Sbjct: 785 HGGRC--ESAPGQLPVCSCPQGWQDPCLNGGSCQD 817
Score = 60.5 bits (140), Expect = 2e-08
Identities = 46/154 (29%), Positives = 70/154 (45%), Gaps = 14/154 (9%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHG 82
RCV+T F C+ G +T C + PC + C D G++ C C +GF G
Sbjct: 410 RCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPC-RNQATCLD-RIGQFTC-ICMAGFTG 466
Query: 83 NGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRER 140
E C+++ C G C++ G C +CP+G+ G CQ D A PC
Sbjct: 467 TYCEVDIDECQSSPCVNGGVCKDRVNGFSC-TCPSGF--SGSTCQLDVDECASTPCRNGA 523
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
+C+ + YEC C G++ G C ++D+C
Sbjct: 524 KCVDQPDG--YECR-CAEGFE--GTLCDRNVDDC 552
Score = 58.0 bits (134), Expect = 1e-07
Identities = 81/307 (26%), Positives = 107/307 (34%), Gaps = 52/307 (16%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQD---LPDGRYQCGKCP 77
G RC CP + C + PC GR CQ R+ C +CP
Sbjct: 55 GGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPC-AGRGVCQSSVVAGTARFSC-RCP 112
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ---HVCDAQK 134
GF G C ++ C G C G SCP GY GR C+ C +
Sbjct: 113 RGFRGPDCSLPD-PCLSSPCAHGARCSVGPDGRFLCSCPPGY--QGRSCRSDVDECRVGE 169
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXX 194
PC C+ +T + C+ CP+GY G C E + PC CRN
Sbjct: 170 PCRHGGTCL--NTPGSFRCQ-CPAGY--TGPLC----ENPAV-PCAP-SPCRNGGTCRQS 218
Query: 195 XXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQG 254
G+ G E V+VD+C R C G CV+
Sbjct: 219 GDLTYDCACLPGFEGQNCE------VNVDDCPGHR--CLNGGTCVDG-----------VN 259
Query: 255 SYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRR----FNAVCGFGQKCVCNTGWTGN 310
+Y C C + T + C + D + P+ C FN + G CVC GWTG
Sbjct: 260 TYNC-QCPPEW---TGQFCTE-DVDECQLQPNACHNGGTCFNTL--GGHSCVCVNGWTGE 312
Query: 311 GTVCGLD 317
+D
Sbjct: 313 SCSQNID 319
Score = 57.6 bits (133), Expect = 2e-07
Identities = 84/313 (26%), Positives = 118/313 (37%), Gaps = 39/313 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C+D F C G + + C ++PC G V C+D +G + C CPSGF G+
Sbjct: 449 CLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGV-CKDRVNG-FSC-TCPSGFSGS 505
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERR 141
+ C + C G C + G +C C G+ +G C D + PC R
Sbjct: 506 TCQLDVDECASTPCRNGAKCVDQPDGYEC-RCAEGF--EGTLCDRNVDDCSPDPC-HHGR 561
Query: 142 CMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXX 200
C+ S + C C GY G C +DEC +PC C +
Sbjct: 562 CVDGIAS--FSC-ACAPGY--TGTRCESQVDEC-RSQPCRHGGKCLD-------LVDKYL 608
Query: 201 XXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRL-CVNTPQYPSNPVSSLQ-GSYIC 258
G G E + C + C G R CV P + + P+ +++
Sbjct: 609 CRCPSGTTGVNCEVNIDDCAS-NPCTFGVCRDGINRYDCVCQPGF-TGPLCNVEINECAS 666
Query: 259 VPCG-GHYYV---NTTRPCFDPDSLVKRC-DPSY-CRR---FNAVC---GFGQKCVCNTG 306
PCG G V N R P SL C PS+ C + +C G +CVC G
Sbjct: 667 SPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPG 726
Query: 307 WTGNGTVCGLDRD 319
W+G L RD
Sbjct: 727 WSGPRCSQSLARD 739
Score = 56.0 bits (129), Expect = 5e-07
Identities = 81/298 (27%), Positives = 111/298 (37%), Gaps = 49/298 (16%)
Query: 28 DQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGV-- 85
D + C PG + + + C + C G C D + Y C +CP + G
Sbjct: 220 DLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGT-CVDGVN-TYNC-QCPPEWTGQFCTE 276
Query: 86 ECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD-AQKPCGRERRCMP 144
+ + N C G +C T G C C G+ G+ Q++ D A C C
Sbjct: 277 DVDECQLQPNACHNGGTCFNTLGGHSC-VCVNGWTGESCS-QNIDDCATAVCFHGATCHD 334
Query: 145 KSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXS 204
+ S Y C CP G G C +D+ + PC + C
Sbjct: 335 RVASFY--C-ACPMGK--TGLLC-HLDDACVSNPCHEDAICDTNPVNGRAICTC-----P 383
Query: 205 QGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGH 264
G+ G ++ DVDEC+ G C CVNT QGS++C CG
Sbjct: 384 PGFTGGACDQ------DVDECSIGANPCEHLGRCVNT-----------QGSFLC-QCGRG 425
Query: 265 YYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC--GFGQ-KCVCNTGWTGNGTVCGLDRD 319
Y T P + D V C CR A C GQ C+C G+T GT C +D D
Sbjct: 426 Y----TGPRCETD--VNECLSGPCRN-QATCLDRIGQFTCICMAGFT--GTYCEVDID 474
Score = 56.0 bits (129), Expect = 5e-07
Identities = 49/175 (28%), Positives = 64/175 (36%), Gaps = 16/175 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRT---ACSANP--CFGGRVPCQDLPDGRYQCGK 75
G CVD + C+ CP T GQ C C P C G L G + C
Sbjct: 251 GGTCVDGVNTYNCQ-CPPEWT--GQFCTEDVDECQLQPNACHNGGTCFNTL--GGHSC-V 304
Query: 76 CPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
C +G+ G C CF G +C + C +CP G G C P
Sbjct: 305 CVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYC-ACPMGKTGLLCHLDDAC-VSNP 362
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDL-IRPCDDLVSCRNEE 189
C + C + C CP G+ G D+DEC + PC+ L C N +
Sbjct: 363 CHEDAICDTNPVNGRAICT-CPPGFT-GGACDQDVDECSIGANPCEHLGRCVNTQ 415
Score = 55.2 bits (127), Expect = 9e-07
Identities = 45/142 (31%), Positives = 58/142 (40%), Gaps = 10/142 (7%)
Query: 19 CVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPC-FGGRVPCQDLPDGRYQCGKCP 77
C RCVD F C PG + ++ C + PC GG+ C DL D +Y C +CP
Sbjct: 557 CHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGK--CLDLVD-KYLC-RCP 612
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCG 137
SG G E C +N C GV C + C C G+ G + A PCG
Sbjct: 613 SGTTGVNCEVNIDDCASNPCTFGV-CRDGINRYDC-VCQPGFTGPLCNVEINECASSPCG 670
Query: 138 RERRCMPKSTSPYYECEGCPSG 159
C+ + C CP G
Sbjct: 671 EGGSCVDGENG--FRCL-CPPG 689
Score = 52.4 bits (120), Expect = 6e-06
Identities = 35/99 (35%), Positives = 43/99 (43%), Gaps = 5/99 (5%)
Query: 26 DTDQGFRCERCPGSQTSDGQTCRTACSANPC-FGGRVPCQDLPDG--RYQCGKCPSGFHG 82
D GFRC G QT + C + PC GG+ P G + C C F G
Sbjct: 1176 DPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTC-HCAQPFWG 1234
Query: 83 NGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG 121
E SCR C GV C++T GP+C +CP G G
Sbjct: 1235 PRCERVARSCRELQCPVGVPCQQTPRGPRC-ACPPGLSG 1272
Score = 47.6 bits (108), Expect = 2e-04
Identities = 45/149 (30%), Positives = 56/149 (37%), Gaps = 14/149 (9%)
Query: 44 GQTCRTACSANPCF-GGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCF-QGV 101
G +PC GGR C LP C CP G+ G + C + C +GV
Sbjct: 40 GAAAPPCLDGSPCANGGR--CTQLPSREAAC-LCPPGWVGERCQL-EDPCHSGPCAGRGV 95
Query: 102 SCEETQYGPKCGSC--PTGYVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSG 159
G SC P G+ G C PC RC + C CP G
Sbjct: 96 CQSSVVAGTARFSCRCPRGFRGPDCSLPDPC-LSSPCAHGARCSVGPDGRFL-CS-CPPG 152
Query: 160 YQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
YQ G +C D+DEC + PC +C N
Sbjct: 153 YQ--GRSCRSDVDECRVGEPCRHGGTCLN 179
Score = 47.2 bits (107), Expect = 2e-04
Identities = 45/167 (26%), Positives = 60/167 (35%), Gaps = 14/167 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D F C PG C +NPC G C D + C CP G+
Sbjct: 812 GGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGT--CTDHV-ASFTC-TCPPGY 867
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C ++CF G +C + C C GY G CQH D +PC
Sbjct: 868 GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSC-LCRPGYT--GAHCQHEADPCLSRPCLH 924
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSC 185
C + P + C S + G C + + +PC + C
Sbjct: 925 GGVC--SAAHPGFRCTCLES---FTGPQCQTLVDWCSRQPCQNGGRC 966
Score = 42.3 bits (95), Expect = 0.007
Identities = 49/176 (27%), Positives = 69/176 (39%), Gaps = 21/176 (11%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G CVD F C PG + Q C + PC G V C G ++C C F
Sbjct: 887 GGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGV-CSAAHPG-FRC-TCLESF 943
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG---DGRQ--CQHVC----- 130
G + C C G C +T G C CP G+ G D R C+
Sbjct: 944 TGPQCQTLVDWCSRQPCQNGGRCVQT--GAYC-LCPPGWSGRLCDIRSLPCREAAAQIGV 1000
Query: 131 DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCR 186
++ C +C+ + +S Y C CP G + + ++D C L +PC +CR
Sbjct: 1001 RLEQLCQAGGQCVDEDSSHY--CV-CPEG-RTGSHCEQEVDPC-LAQPCQHGGTCR 1051
Score = 41.5 bits (93), Expect = 0.011
Identities = 49/183 (26%), Positives = 64/183 (34%), Gaps = 20/183 (10%)
Query: 63 CQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGD 122
C D D + C CP G G+ E C A C G +C G C C GY GD
Sbjct: 1012 CVD-EDSSHYC-VCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMC-ECLPGYNGD 1068
Query: 123 GRQCQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPC 179
C+ D A +PC C+ Y C CP G G C ++ D+C P
Sbjct: 1069 --NCEDDVDECASQPCQHGGSCI--DLVARYLC-SCPPGTL--GVLCEINEDDCGPGPPL 1121
Query: 180 DDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCV 239
D C + G+ G E D++EC G + R C+
Sbjct: 1122 DSGPRCLH-NGTCVDLVGGFRCTCPPGYTGLRCE------ADINECRSGACHAAHTRDCL 1174
Query: 240 NTP 242
P
Sbjct: 1175 QDP 1177
Score = 38.7 bits (86), Expect = 0.081
Identities = 32/108 (29%), Positives = 41/108 (37%), Gaps = 11/108 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C G+ CE PG + + C++ PC G C DL RY C CP G
Sbjct: 1047 GGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGG-SCIDLV-ARYLC-SCPPGT 1103
Query: 81 HGNGVECYRISC-------RANTCFQGVSCEETQYGPKCGSCPTGYVG 121
G E C C +C + G +C +CP GY G
Sbjct: 1104 LGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRC-TCPPGYTG 1150
Score = 34.3 bits (75), Expect = 1.7
Identities = 37/135 (27%), Positives = 52/135 (38%), Gaps = 16/135 (11%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCF--GGRV----PCQDLPDGRYQCG 74
G C+D + C PG+ + C P G R C DL G ++C
Sbjct: 1085 GGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGG-FRC- 1142
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVS--CEETQYGPKCGSCPTGYVGDGRQCQHV--- 129
CP G+ G E CR+ C + C + G C G+ G +CQ V
Sbjct: 1143 TCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGF--SGPRCQTVLSP 1200
Query: 130 CDAQKPCGRERRCMP 144
C++Q PC +C P
Sbjct: 1201 CESQ-PCQHGGQCRP 1214
>BC022497-1|AAH22497.1| 683|Homo sapiens fibulin 1 protein.
Length = 683
Score = 63.3 bits (147), Expect = 3e-09
Identities = 82/316 (25%), Positives = 125/316 (39%), Gaps = 56/316 (17%)
Query: 56 CFGG---RVPCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-C--RANTCFQGVSCEETQ 107
C GG + C+D D C C G+ +GV C ++ C +++C G SC T
Sbjct: 180 CRGGGPCKQQCRDTGD-EVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTV 237
Query: 108 YGPKC---GSCPTGY-VGDGRQCQHVCDAQKPCGRERRCMP----KSTSPYYECEG---C 156
+C SC TGY + + C+ + + + C+P ++T + C C
Sbjct: 238 GSFRCQRDSSCGTGYELTEDNSCKDIDECESGI---HNCLPDFICQNTLGSFRCRPKLQC 294
Query: 157 PSGYQWNGY-TCVDMDEC-DLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNER 214
SG+ + C+D++EC + PC +C N E RG
Sbjct: 295 KSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCG-----RGYHLNE 349
Query: 215 RREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCF 274
CVDVDECA C +G CVN+P GS+ C G+Y+ +R C
Sbjct: 350 EGTRCVDVDECAPPAEPCGKGHRCVNSP-----------GSFRCECKTGYYFDGISRMCV 398
Query: 275 DPDSLVKRCDPSYCRRF-NAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQL-PCNE 332
D + C+R+ +C G KC G G +DG E + C+
Sbjct: 399 DVNE---------CQRYPGRLC--GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSS 447
Query: 333 PRCKKDNCPDVSNSGQ 348
C ++ C +V S Q
Sbjct: 448 SPCSQE-CANVYGSYQ 462
Score = 62.9 bits (146), Expect = 4e-09
Identities = 69/243 (28%), Positives = 101/243 (41%), Gaps = 41/243 (16%)
Query: 20 VGERCVDTDQGFRCER----CPGSQ--TSDGQTC----RTACSANPCFGGRVPCQDLPDG 69
+G C++T+ + C++ C +G C A A PC G C + P G
Sbjct: 321 IGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGH-RCVNSP-G 378
Query: 70 RYQCGKCPSGFHGNGVECYRISCRANTCFQ------GVSCEETQYGPKCGSCPTGY--VG 121
++C +C +G++ +G+ R+ N C + G CE T C SC G+
Sbjct: 379 SFRC-ECKTGYYFDGIS--RMCVDVNECQRYPGRLCGHKCENTLGSYLC-SCSVGFRLSV 434
Query: 122 DGRQCQHVCD-AQKPCGRERRCMPKSTSPYYECEGCPSGYQWN---GYTCVDMDECDLIR 177
DGR C+ + + + PC +E C S Y+C C GYQ + G TC D+DEC L
Sbjct: 435 DGRSCEDINECSSSPCSQE--CANVYGS--YQCY-CRRGYQLSDVDGVTCEDIDECAL-- 487
Query: 178 PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRL 237
P + C S G+R N +C D+DEC G NC
Sbjct: 488 PTGGHI-C--SYRCINIPGSFQCSCPSSGYRLAPN---GSNCQDIDECVTGIHNCSINET 541
Query: 238 CVN 240
C N
Sbjct: 542 CFN 544
Score = 57.2 bits (132), Expect = 2e-07
Identities = 57/196 (29%), Positives = 86/196 (43%), Gaps = 32/196 (16%)
Query: 5 SMGDAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTAC-SANPCFGGRVP 62
S D +T C +GE C++T FRC+R T T +C + C G
Sbjct: 213 SCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHN 272
Query: 63 CQDLPD-------GRYQCG---KCPSGF----HGNGVECYRISCRANTCFQGVSCEETQY 108
C LPD G ++C +C SGF GN ++ + C G +C T+
Sbjct: 273 C--LPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEG 330
Query: 109 GPKC----GSCPTGY--VGDGRQCQHVCDA---QKPCGRERRCMPKSTSPYYECEGCPSG 159
C +C GY +G +C V + +PCG+ RC+ S + CE C +G
Sbjct: 331 SYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGS--FRCE-CKTG 387
Query: 160 YQWNGYT--CVDMDEC 173
Y ++G + CVD++EC
Sbjct: 388 YYFDGISRMCVDVNEC 403
Score = 52.4 bits (120), Expect = 6e-06
Identities = 63/199 (31%), Positives = 84/199 (42%), Gaps = 29/199 (14%)
Query: 8 DAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPC--FGGRV--- 61
D P + C G RCV++ FRCE C DG + R N C + GR+
Sbjct: 356 DVDECAPPAEPCGKGHRCVNSPGSFRCE-CKTGYYFDGIS-RMCVDVNECQRYPGRLCGH 413
Query: 62 PCQDLPDGRYQCGKCPSGFH--GNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTG 118
C++ G Y C C GF +G C I+ C ++ C Q C YG C G
Sbjct: 414 KCENTL-GSYLCS-CSVGFRLSVDGRSCEDINECSSSPCSQ--ECANV-YGSYQCYCRRG 468
Query: 119 YV---GDGRQCQHVCDAQKPCGRE---RRCMPKSTSPYYECEGCPS-GYQW--NGYTCVD 169
Y DG C+ + + P G RC+ S ++C CPS GY+ NG C D
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS--FQCS-CPSSGYRLAPNGSNCQD 525
Query: 170 MDECDL-IRPCDDLVSCRN 187
+DEC I C +C N
Sbjct: 526 IDECVTGIHNCSINETCFN 544
>AY358336-1|AAQ88702.1| 509|Homo sapiens DFLL295 protein.
Length = 509
Score = 63.3 bits (147), Expect = 3e-09
Identities = 69/212 (32%), Positives = 87/212 (41%), Gaps = 35/212 (16%)
Query: 109 GPKCGSCPTGYVGDG-RQCQHVCDAQ-KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYT 166
GP C GY G Q + C + +PC + RCM +T Y+C Y NGY
Sbjct: 71 GPNKCKCHPGYAGKTCNQDLNECGLKPRPC--KHRCM--NTYGSYKC------YCLNGYM 120
Query: 167 CVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECA 226
+ C C + +C + S G + R CVDVDECA
Sbjct: 121 LMPDGSCSSALTCS-MANC--QYGCDVVKGQIRCQCPSPGLHLAPDGRT---CVDVDECA 174
Query: 227 DGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGH--YYVNTTRPCFDPD--SLVKR 282
GRA+CPR R CVNT GSYIC G Y+ C D D SL +
Sbjct: 175 TGRASCPRFRQCVNT-----------FGSYICKCHKGFDLMYIGGKYQCHDIDECSLGQY 223
Query: 283 CDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
S+ R +N V G KC C G+ G+G C
Sbjct: 224 QCSSFARCYN-VRG-SYKCKCKEGYQGDGLTC 253
Score = 46.0 bits (104), Expect = 5e-04
Identities = 49/161 (30%), Positives = 69/161 (42%), Gaps = 24/161 (14%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGKCPS-G 79
RC++T ++C G +C +A CS C G C D+ G+ +C +CPS G
Sbjct: 103 RCMNTYGSYKCYCLNGYMLMPDGSCSSALTCSMANCQYG---C-DVVKGQIRC-QCPSPG 157
Query: 80 FH--GNGVECYRIS-CRAN--TCFQGVSCEETQYGPKCGSCPTG----YVGDGRQCQHV- 129
H +G C + C +C + C T +G C G Y+G QC +
Sbjct: 158 LHLAPDGRTCVDVDECATGRASCPRFRQCVNT-FGSYICKCHKGFDLMYIGGKYQCHDID 216
Query: 130 -CD-AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV 168
C Q C RC S Y+C+ C GYQ +G TCV
Sbjct: 217 ECSLGQYQCSSFARCYNVRGS--YKCK-CKEGYQGDGLTCV 254
Score = 41.5 bits (93), Expect = 0.011
Identities = 45/166 (27%), Positives = 65/166 (39%), Gaps = 16/166 (9%)
Query: 32 RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDL---PDGRYQCGKCPSGFH--GNGVE 86
+C+ PG G+TC N C PC+ G Y+C C +G+ +G
Sbjct: 74 KCKCHPGYA---GKTCNQ--DLNECGLKPRPCKHRCMNTYGSYKC-YCLNGYMLMPDGSC 127
Query: 87 CYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA---QKPCGRERRCM 143
++C C G + Q +C S DGR C V + + C R R+C+
Sbjct: 128 SSALTCSMANCQYGCDVVKGQIRCQCPSPGLHLAPDGRTCVDVDECATGRASCPRFRQCV 187
Query: 144 PKSTSPYYEC-EGCPSGYQWNGYTCVDMDECDLIR-PCDDLVSCRN 187
S +C +G Y Y C D+DEC L + C C N
Sbjct: 188 NTFGSYICKCHKGFDLMYIGGKYQCHDIDECSLGQYQCSSFARCYN 233
Score = 37.1 bits (82), Expect = 0.25
Identities = 32/110 (29%), Positives = 39/110 (35%), Gaps = 15/110 (13%)
Query: 32 RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPD-----GRYQCGKCPSGFH----G 82
RC+ CP RT + C GR C G Y C KC GF G
Sbjct: 150 RCQ-CPSPGLHLAPDGRTCVDVDECATGRASCPRFRQCVNTFGSYIC-KCHKGFDLMYIG 207
Query: 83 NGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV 129
+C+ I C C C + KC C GY GDG C ++
Sbjct: 208 GKYQCHDIDECSLGQYQCSSFARCYNVRGSYKC-KCKEGYQGDGLTCVYI 256
>AY311388-1|AAP74958.1| 2551|Homo sapiens FEX2 protein.
Length = 2551
Score = 62.5 bits (145), Expect = 6e-09
Identities = 45/160 (28%), Positives = 62/160 (38%), Gaps = 17/160 (10%)
Query: 20 VGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
+G+ D D G+R C + T D C C + C DG C KC +G
Sbjct: 1411 LGDGSCDCDVGWRGVHCDNATTEDN--CNGTCHTS------ANCLTNSDGTASC-KCAAG 1461
Query: 80 FHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--C-DAQ 133
F GNG C I+ C + C C+ T G + +C GY GDG C + C +
Sbjct: 1462 FQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENH 1521
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC 173
C + C T P C Y +G C ++ C
Sbjct: 1522 GGCDKNAEC--TQTGPNQAACNCLPAYTGDGKVCTLINVC 1559
Score = 54.4 bits (125), Expect = 2e-06
Identities = 38/121 (31%), Positives = 50/121 (41%), Gaps = 8/121 (6%)
Query: 13 VTPFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSAN-PCFGG---RVPCQDLPD 68
+TP C+ T G C T +G+ C + P GG C +
Sbjct: 874 LTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGP 933
Query: 69 GRYQCGKCPSGFHGNGVECYRI-SCRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQ 125
G+ +C +C GF GNG++C I SC T C SC+ T G C GY GDG
Sbjct: 934 GQNEC-ECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGDGFL 992
Query: 126 C 126
C
Sbjct: 993 C 993
Score = 52.0 bits (119), Expect = 8e-06
Identities = 75/308 (24%), Positives = 111/308 (36%), Gaps = 54/308 (17%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHG 82
+CV T C C G Q C + N CFG + C D +G C +C GF G
Sbjct: 1326 KCVRTVITREC--CAGFFGPQCQPC-PGNAQNVCFGNGI-CLDGVNGTGVC-ECGEGFSG 1380
Query: 83 NGVE-C----YRISC-RANTCFQGVSCEETQYGPKCGSCPTGYVG---DGRQCQHVCDAQ 133
E C Y I C +A +C G C + G C G+ G D + C+
Sbjct: 1381 TACETCTEGKYGIHCDQACSCVHG-RCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGT 1439
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIR-PCDDLVSCRNEEXXX 192
C C+ S C+ C +G+Q NG C ++ C++ C C+
Sbjct: 1440 --CHTSANCLTNSDGTA-SCK-CAAGFQGNGTICTAINACEISNGGCSAKADCKR----- 1490
Query: 193 XXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSL 252
G+ G G C++++ C + C + C T P+
Sbjct: 1491 -TTPGRRVCTCKAGYTGDGIV-----CLEINPCLENHGGCDKNAECTQTG--PN------ 1536
Query: 253 QGSYICVPCGGHYYVNTTRPCFDPDSLVKRC--DPSYCRRFNAVCGF-GQ---KCVCNTG 306
Q + C+P Y + C +L+ C C F A+C GQ C C
Sbjct: 1537 QAACNCLPA----YTGDGKVC----TLINVCLTKNGGCSEF-AICNHTGQVERTCTCKPN 1587
Query: 307 WTGNGTVC 314
+ G+G C
Sbjct: 1588 YIGDGFTC 1595
Score = 51.6 bits (118), Expect = 1e-05
Identities = 81/301 (26%), Positives = 108/301 (35%), Gaps = 56/301 (18%)
Query: 32 RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS 91
RC CPG D C + +PC GR C + +G C C GF G E +
Sbjct: 99 RC--CPGRWGPDCIECPGG-AGSPC-NGRGSCAEGMEGNGTCS-CQEGFGGTACE----T 149
Query: 92 CRANTCFQGVSCEETQYGPKCGSCPTGYVGDGR-QCQHV-----CDAQKP------CGRE 139
C + F G SC G C +G GDG +C CD P C
Sbjct: 150 CADDNLF-GPSCSSV-CNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPEN 207
Query: 140 RRCMPKSTSPY-YECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXX 198
RC P + EC+ C Y+ +G CD I PC + C
Sbjct: 208 SRCSPSTEDENKLECK-CLPNYRGDG------KYCDPINPCLRKI-CHPHAHCTYLGPNR 259
Query: 199 XXXXXSQGWRGTGNERRREHCVDVDECADGRANCP-RGRLCVNTPQYPSNPVSSLQGSYI 257
+G+RG G + C+ VD C NCP + +C +Y G
Sbjct: 260 HSCTCQEGYRGDG-----QVCLPVDPCQINFGNCPTKSTVC----KYDG------PGQSH 304
Query: 258 CVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQ-KCVCNTGWTGNGTV 313
C C HY + K +P C R NA C G+ +C+C G+ G+G
Sbjct: 305 C-ECKEHYQNFVPGVGCSMTDICKSDNP--CHR-NANCTTVAPGRTECICQKGYVGDGLT 360
Query: 314 C 314
C
Sbjct: 361 C 361
Score = 51.6 bits (118), Expect = 1e-05
Identities = 48/185 (25%), Positives = 71/185 (38%), Gaps = 20/185 (10%)
Query: 18 LCVGERC---VDTDQGFRCERCPGSQTSDGQTC---RTACSANPCFGGRVPCQDLPDGRY 71
LCV C +D+D C S G+ C +AC F + +G
Sbjct: 793 LCVHGTCNNRIDSDGACLTGTCRDG--SAGRLCDKQTSACGPYVQFCHIHATCEYSNGTA 850
Query: 72 QCGKCPSGFHGNGVECYRIS-CRANT---CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ 127
C C +G+ G+G C + C T C + C +T G C G+ G+GR C
Sbjct: 851 SC-ICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCS 909
Query: 128 HVCDAQKP----CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDL 182
+ + P C C+ ECE C G++ NG C + C + C L
Sbjct: 910 EINNCLLPSAGGCHDNASCLYVGPG-QNECE-CKKGFRGNGIDCEPITSCLEQTGKCHPL 967
Query: 183 VSCRN 187
SC++
Sbjct: 968 ASCQS 972
Score = 47.2 bits (107), Expect = 2e-04
Identities = 44/160 (27%), Positives = 63/160 (39%), Gaps = 22/160 (13%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C + G CE C G +C + C+ C G C DG C +C S + G
Sbjct: 138 CQEGFGGTACETCADDNLF-GPSCSSVCN---CVHG--VCNSGLDGDGTC-ECYSAYTGP 190
Query: 84 GVECYRISCRANTCFQGVSCE---ETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
+ C A C + C E + +C C Y GDG+ C D PC R +
Sbjct: 191 KCDKPIPECAALLCPENSRCSPSTEDENKLEC-KCLPNYRGDGKYC----DPINPCLR-K 244
Query: 141 RCMPKSTSPY-----YECEGCPSGYQWNGYTCVDMDECDL 175
C P + Y + C C GY+ +G C+ +D C +
Sbjct: 245 ICHPHAHCTYLGPNRHSCT-CQEGYRGDGQVCLPVDPCQI 283
Score = 47.2 bits (107), Expect = 2e-04
Identities = 49/172 (28%), Positives = 68/172 (39%), Gaps = 24/172 (13%)
Query: 23 RCVDTDQGFRCERC-PGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
+C G CE C PG D C CS + G+ C D G QC C +G+
Sbjct: 1987 KCNTGFNGTACEMCWPGRFGPDCLPC--GCSDH----GQ--CDDGITGSGQC-LCETGWT 2037
Query: 82 GNGVECYRISCRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKP-C 136
G + + T C +C+E C C Y GDG C V C C
Sbjct: 2038 GPSCDTQAVLPAVCTPPCSAHATCKENN---TC-ECNLDYEGDGITCTVVDFCKQDNGGC 2093
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC--DLIRPCDDLVSCR 186
+ RC K T C C GY+ +G++C ++D C L C + +C+
Sbjct: 2094 AKVARCSQKGTK--VSCS-CQKGYKGDGHSCTEIDPCADGLNGGCHEHATCK 2142
Score = 42.3 bits (95), Expect = 0.007
Identities = 46/177 (25%), Positives = 64/177 (36%), Gaps = 45/177 (25%)
Query: 92 CRANTCFQGVSCE---ETQYGPKC--------GSCPTGYVGDGR-QCQ-----HVCDAQ- 133
C+ NT F G +CE ++GP C G C G G G+ C+ CD Q
Sbjct: 1986 CKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQA 2045
Query: 134 -------KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIR-PCDDLVSC 185
PC C +T CE C Y+ +G TC +D C C + C
Sbjct: 2046 VLPAVCTPPCSAHATCKENNT-----CE-CNLDYEGDGITCTVVDFCKQDNGGCAKVARC 2099
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADG-RANCPRGRLCVNT 241
+ +G++G G+ C ++D CADG C C T
Sbjct: 2100 SQK-------GTKVSCSCQKGYKGDGHS-----CTEIDPCADGLNGGCHEHATCKMT 2144
Score = 37.1 bits (82), Expect = 0.25
Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 8/101 (7%)
Query: 33 CERCPGSQTSDGQTCRTACSANPCFGG--RVPCQDLPDGRYQCGKCPSGFHGNGVECYRI 90
CE C DG TC GG +V + C C G+ G+G C I
Sbjct: 2067 CE-CNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCS-CQKGYKGDGHSCTEI 2124
Query: 91 SCRANT----CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ 127
A+ C + +C+ T G C + YVGDG C+
Sbjct: 2125 DPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCE 2165
Score = 33.1 bits (72), Expect = 4.0
Identities = 18/34 (52%), Positives = 18/34 (52%), Gaps = 5/34 (14%)
Query: 285 PSYCRRFNAVC---GFG-QKCVCNTGWTGNGTVC 314
P C R NA C G G CVC GWTGNG C
Sbjct: 876 PGGCSR-NAECIKTGTGTHTCVCQQGWTGNGRDC 908
>AK074051-1|BAB84877.1| 1736|Homo sapiens FLJ00122 protein protein.
Length = 1736
Score = 62.5 bits (145), Expect = 6e-09
Identities = 45/160 (28%), Positives = 62/160 (38%), Gaps = 17/160 (10%)
Query: 20 VGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
+G+ D D G+R C + T D C C + C DG C KC +G
Sbjct: 596 LGDGSCDCDVGWRGVHCDNATTEDN--CNGTCHTS------ANCLTNSDGTASC-KCAAG 646
Query: 80 FHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--C-DAQ 133
F GNG C I+ C + C C+ T G + +C GY GDG C + C +
Sbjct: 647 FQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENH 706
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC 173
C + C T P C Y +G C ++ C
Sbjct: 707 GGCDKNAEC--TQTGPNQAACNCLPAYTGDGKVCTLINVC 744
Score = 54.4 bits (125), Expect = 2e-06
Identities = 38/121 (31%), Positives = 50/121 (41%), Gaps = 8/121 (6%)
Query: 13 VTPFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSAN-PCFGG---RVPCQDLPD 68
+TP C+ T G C T +G+ C + P GG C +
Sbjct: 59 LTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGP 118
Query: 69 GRYQCGKCPSGFHGNGVECYRI-SCRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQ 125
G+ +C +C GF GNG++C I SC T C SC+ T G C GY GDG
Sbjct: 119 GQNEC-ECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGDGFL 177
Query: 126 C 126
C
Sbjct: 178 C 178
Score = 52.0 bits (119), Expect = 8e-06
Identities = 75/308 (24%), Positives = 111/308 (36%), Gaps = 54/308 (17%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHG 82
+CV T C C G Q C + N CFG + C D +G C +C GF G
Sbjct: 511 KCVRTVITREC--CAGFFGPQCQPC-PGNAQNVCFGNGI-CLDGVNGTGVC-ECGEGFSG 565
Query: 83 NGVE-C----YRISC-RANTCFQGVSCEETQYGPKCGSCPTGYVG---DGRQCQHVCDAQ 133
E C Y I C +A +C G C + G C G+ G D + C+
Sbjct: 566 TACETCTEGKYGIHCDQACSCVHG-RCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGT 624
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIR-PCDDLVSCRNEEXXX 192
C C+ S C+ C +G+Q NG C ++ C++ C C+
Sbjct: 625 --CHTSANCLTNSDGTA-SCK-CAAGFQGNGTICTAINACEISNGGCSAKADCKR----- 675
Query: 193 XXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSL 252
G+ G G C++++ C + C + C T P+
Sbjct: 676 -TTPGRRVCTCKAGYTGDGIV-----CLEINPCLENHGGCDKNAECTQTG--PN------ 721
Query: 253 QGSYICVPCGGHYYVNTTRPCFDPDSLVKRC--DPSYCRRFNAVCGF-GQ---KCVCNTG 306
Q + C+P Y + C +L+ C C F A+C GQ C C
Sbjct: 722 QAACNCLPA----YTGDGKVC----TLINVCLTKNGGCSEF-AICNHTGQVERTCTCKPN 772
Query: 307 WTGNGTVC 314
+ G+G C
Sbjct: 773 YIGDGFTC 780
Score = 51.2 bits (117), Expect = 1e-05
Identities = 33/121 (27%), Positives = 50/121 (41%), Gaps = 11/121 (9%)
Query: 76 CPSGFHGNGVECYRIS-CRANT---CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
C +G+ G+G C + C T C + C +T G C G+ G+GR C + +
Sbjct: 39 CKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINN 98
Query: 132 AQKP----CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDLVSCR 186
P C C+ ECE C G++ NG C + C + C L SC+
Sbjct: 99 CLLPSAGGCHDNASCLYVGPG-QNECE-CKKGFRGNGIDCEPITSCLEQTGKCHPLASCQ 156
Query: 187 N 187
+
Sbjct: 157 S 157
Score = 48.0 bits (109), Expect = 1e-04
Identities = 49/172 (28%), Positives = 68/172 (39%), Gaps = 24/172 (13%)
Query: 23 RCVDTDQGFRCERC-PGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
+C G CE C PG D C CS + G+ C D G QC C +G+
Sbjct: 1172 KCNTGFNGTACEMCWPGRFGPDCLPC--GCSDH----GQ--CDDGITGSGQC-LCETGWT 1222
Query: 82 GNGVECYRISCRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKP-C 136
G + + T C +C+E C C Y GDG C V C C
Sbjct: 1223 GTSCDTQAVLPAVCTPPCSAHATCKENN---TC-ECNLDYEGDGITCTVVDFCKQDNGGC 1278
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC--DLIRPCDDLVSCR 186
+ RC K T C C GY+ +G++C ++D C L C + +C+
Sbjct: 1279 AKVARCSQKGTK--VSCS-CQKGYKGDGHSCTEIDPCADGLNGGCHEHATCK 1327
Score = 42.3 bits (95), Expect = 0.007
Identities = 46/177 (25%), Positives = 64/177 (36%), Gaps = 45/177 (25%)
Query: 92 CRANTCFQGVSCE---ETQYGPKC--------GSCPTGYVGDGR-QCQ-----HVCDAQ- 133
C+ NT F G +CE ++GP C G C G G G+ C+ CD Q
Sbjct: 1171 CKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGTSCDTQA 1230
Query: 134 -------KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIR-PCDDLVSC 185
PC C +T CE C Y+ +G TC +D C C + C
Sbjct: 1231 VLPAVCTPPCSAHATCKENNT-----CE-CNLDYEGDGITCTVVDFCKQDNGGCAKVARC 1284
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADG-RANCPRGRLCVNT 241
+ +G++G G+ C ++D CADG C C T
Sbjct: 1285 SQK-------GTKVSCSCQKGYKGDGHS-----CTEIDPCADGLNGGCHEHATCKMT 1329
Score = 37.1 bits (82), Expect = 0.25
Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 8/101 (7%)
Query: 33 CERCPGSQTSDGQTCRTACSANPCFGG--RVPCQDLPDGRYQCGKCPSGFHGNGVECYRI 90
CE C DG TC GG +V + C C G+ G+G C I
Sbjct: 1252 CE-CNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCS-CQKGYKGDGHSCTEI 1309
Query: 91 SCRANT----CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ 127
A+ C + +C+ T G C + YVGDG C+
Sbjct: 1310 DPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCE 1350
Score = 33.1 bits (72), Expect = 4.0
Identities = 18/34 (52%), Positives = 18/34 (52%), Gaps = 5/34 (14%)
Query: 285 PSYCRRFNAVC---GFG-QKCVCNTGWTGNGTVC 314
P C R NA C G G CVC GWTGNG C
Sbjct: 61 PGGCSR-NAECIKTGTGTHTCVCQQGWTGNGRDC 93
Score = 31.9 bits (69), Expect = 9.2
Identities = 25/68 (36%), Positives = 31/68 (45%), Gaps = 9/68 (13%)
Query: 274 FDPDSLVKRC-DPSYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCN- 331
F PD L C D C + + G GQ C+C TGWT GT C L PC+
Sbjct: 1190 FGPDCLPCGCSDHGQCD--DGITGSGQ-CLCETGWT--GTSCDTQAVLPAVCTP--PCSA 1242
Query: 332 EPRCKKDN 339
CK++N
Sbjct: 1243 HATCKENN 1250
>AK024503-1|BAB15793.1| 1192|Homo sapiens FLJ00112 protein protein.
Length = 1192
Score = 62.5 bits (145), Expect = 6e-09
Identities = 45/160 (28%), Positives = 62/160 (38%), Gaps = 17/160 (10%)
Query: 20 VGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
+G+ D D G+R C + T D C C + C DG C KC +G
Sbjct: 52 LGDGSCDCDVGWRGVHCDNATTEDN--CNGTCHTS------ANCLTNSDGTASC-KCAAG 102
Query: 80 FHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--C-DAQ 133
F GNG C I+ C + C C+ T G + +C GY GDG C + C +
Sbjct: 103 FQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENH 162
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC 173
C + C T P C Y +G C ++ C
Sbjct: 163 GGCDKNAEC--TQTGPNQAACNCLPAYTGDGKVCTLINVC 200
Score = 47.2 bits (107), Expect = 2e-04
Identities = 49/172 (28%), Positives = 68/172 (39%), Gaps = 24/172 (13%)
Query: 23 RCVDTDQGFRCERC-PGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
+C G CE C PG D C CS + G+ C D G QC C +G+
Sbjct: 628 KCNTGFNGTACEMCWPGRFGPDCLPC--GCSDH----GQ--CDDGITGSGQC-LCETGWT 678
Query: 82 GNGVECYRISCRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKP-C 136
G + + T C +C+E C C Y GDG C V C C
Sbjct: 679 GPSCDTQAVLPAVCTPPCSAHATCKENN---TC-ECNLDYEGDGITCTVVDFCKQDNGGC 734
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC--DLIRPCDDLVSCR 186
+ RC K T C C GY+ +G++C ++D C L C + +C+
Sbjct: 735 AKVARCSQKGTK--VSCS-CQKGYKGDGHSCTEIDPCADGLNGGCHEHATCK 783
Score = 43.6 bits (98), Expect = 0.003
Identities = 62/263 (23%), Positives = 94/263 (35%), Gaps = 50/263 (19%)
Query: 68 DGRYQCGKCPSGFHGNGVE-C----YRISC-RANTCFQGVSCEETQYGPKCGSCPTGYVG 121
DG C +C GF G E C Y I C +A +C G C + G C G+ G
Sbjct: 8 DGTGVC-ECGEGFSGTACETCTEGKYGIHCDQACSCVHG-RCNQGPLGDGSCDCDVGWRG 65
Query: 122 ---DGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIR- 177
D + C+ C C+ S C+ C +G+Q NG C ++ C++
Sbjct: 66 VHCDNATTEDNCNGT--CHTSANCLTNSDGTA-SCK-CAAGFQGNGTICTAINACEISNG 121
Query: 178 PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRL 237
C C+ G+ G G C++++ C + C +
Sbjct: 122 GCSAKADCKR------TTPGRRVCTCKAGYTGDGIV-----CLEINPCLENHGGCDKNAE 170
Query: 238 CVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRC--DPSYCRRFNAVC 295
C T P+ Q + C+P Y + C +L+ C C F A+C
Sbjct: 171 CTQTG--PN------QAACNCLPA----YTGDGKVC----TLINVCLTKNGGCSEF-AIC 213
Query: 296 GF-GQ---KCVCNTGWTGNGTVC 314
GQ C C + G+G C
Sbjct: 214 NHTGQVERTCTCKPNYIGDGFTC 236
Score = 42.3 bits (95), Expect = 0.007
Identities = 46/177 (25%), Positives = 64/177 (36%), Gaps = 45/177 (25%)
Query: 92 CRANTCFQGVSCE---ETQYGPKC--------GSCPTGYVGDGR-QCQ-----HVCDAQ- 133
C+ NT F G +CE ++GP C G C G G G+ C+ CD Q
Sbjct: 627 CKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQA 686
Query: 134 -------KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIR-PCDDLVSC 185
PC C +T CE C Y+ +G TC +D C C + C
Sbjct: 687 VLPAVCTPPCSAHATCKENNT-----CE-CNLDYEGDGITCTVVDFCKQDNGGCAKVARC 740
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADG-RANCPRGRLCVNT 241
+ +G++G G+ C ++D CADG C C T
Sbjct: 741 SQK-------GTKVSCSCQKGYKGDGHS-----CTEIDPCADGLNGGCHEHATCKMT 785
Score = 37.1 bits (82), Expect = 0.25
Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 8/101 (7%)
Query: 33 CERCPGSQTSDGQTCRTACSANPCFGG--RVPCQDLPDGRYQCGKCPSGFHGNGVECYRI 90
CE C DG TC GG +V + C C G+ G+G C I
Sbjct: 708 CE-CNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCS-CQKGYKGDGHSCTEI 765
Query: 91 SCRANT----CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ 127
A+ C + +C+ T G C + YVGDG C+
Sbjct: 766 DPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCE 806
>AJ295695-1|CAC82105.1| 2551|Homo sapiens stabilin-2 protein.
Length = 2551
Score = 62.5 bits (145), Expect = 6e-09
Identities = 45/160 (28%), Positives = 62/160 (38%), Gaps = 17/160 (10%)
Query: 20 VGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
+G+ D D G+R C + T D C C + C DG C KC +G
Sbjct: 1411 LGDGSCDCDVGWRGVHCDNATTEDN--CNGTCHTS------ANCLTNSDGTASC-KCAAG 1461
Query: 80 FHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--C-DAQ 133
F GNG C I+ C + C C+ T G + +C GY GDG C + C +
Sbjct: 1462 FQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENH 1521
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC 173
C + C T P C Y +G C ++ C
Sbjct: 1522 GGCDKNAEC--TQTGPNQAACNCLPAYTGDGKVCTLINVC 1559
Score = 54.4 bits (125), Expect = 2e-06
Identities = 38/121 (31%), Positives = 50/121 (41%), Gaps = 8/121 (6%)
Query: 13 VTPFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSAN-PCFGG---RVPCQDLPD 68
+TP C+ T G C T +G+ C + P GG C +
Sbjct: 874 LTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGP 933
Query: 69 GRYQCGKCPSGFHGNGVECYRI-SCRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQ 125
G+ +C +C GF GNG++C I SC T C SC+ T G C GY GDG
Sbjct: 934 GQNEC-ECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGDGFL 992
Query: 126 C 126
C
Sbjct: 993 C 993
Score = 52.0 bits (119), Expect = 8e-06
Identities = 75/308 (24%), Positives = 111/308 (36%), Gaps = 54/308 (17%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHG 82
+CV T C C G Q C + N CFG + C D +G C +C GF G
Sbjct: 1326 KCVRTVITREC--CAGFFGPQCQPC-PGNAQNVCFGNGI-CLDGVNGTGVC-ECGEGFSG 1380
Query: 83 NGVE-C----YRISC-RANTCFQGVSCEETQYGPKCGSCPTGYVG---DGRQCQHVCDAQ 133
E C Y I C +A +C G C + G C G+ G D + C+
Sbjct: 1381 TACETCTEGKYGIHCDQACSCVHG-RCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGT 1439
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIR-PCDDLVSCRNEEXXX 192
C C+ S C+ C +G+Q NG C ++ C++ C C+
Sbjct: 1440 --CHTSANCLTNSDGTA-SCK-CAAGFQGNGTICTAINACEISNGGCSAKADCKR----- 1490
Query: 193 XXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSL 252
G+ G G C++++ C + C + C T P+
Sbjct: 1491 -TTPGRRVCTCKAGYTGDGIV-----CLEINPCLENHGGCDKNAECTQTG--PN------ 1536
Query: 253 QGSYICVPCGGHYYVNTTRPCFDPDSLVKRC--DPSYCRRFNAVCGF-GQ---KCVCNTG 306
Q + C+P Y + C +L+ C C F A+C GQ C C
Sbjct: 1537 QAACNCLPA----YTGDGKVC----TLINVCLTKNGGCSEF-AICNHTGQVERTCTCKPN 1587
Query: 307 WTGNGTVC 314
+ G+G C
Sbjct: 1588 YIGDGFTC 1595
Score = 51.6 bits (118), Expect = 1e-05
Identities = 81/301 (26%), Positives = 108/301 (35%), Gaps = 56/301 (18%)
Query: 32 RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS 91
RC CPG D C + +PC GR C + +G C C GF G E +
Sbjct: 99 RC--CPGRWGPDCIECPGG-AGSPC-NGRGSCAEGMEGNGTCS-CQEGFGGTACE----T 149
Query: 92 CRANTCFQGVSCEETQYGPKCGSCPTGYVGDGR-QCQHV-----CDAQKP------CGRE 139
C + F G SC G C +G GDG +C CD P C
Sbjct: 150 CADDNLF-GPSCSSV-CNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPEN 207
Query: 140 RRCMPKSTSPY-YECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXX 198
RC P + EC+ C Y+ +G CD I PC + C
Sbjct: 208 SRCSPSTEDENKLECK-CLPNYRGDG------KYCDPINPCLRKI-CHPHAHCTYLGPNR 259
Query: 199 XXXXXSQGWRGTGNERRREHCVDVDECADGRANCP-RGRLCVNTPQYPSNPVSSLQGSYI 257
+G+RG G + C+ VD C NCP + +C +Y G
Sbjct: 260 HSCTCQEGYRGDG-----QVCLPVDPCQINFGNCPTKSTVC----KYDG------PGQSH 304
Query: 258 CVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQ-KCVCNTGWTGNGTV 313
C C HY + K +P C R NA C G+ +C+C G+ G+G
Sbjct: 305 C-ECKEHYQNFVPGVGCSMTDICKSDNP--CHR-NANCTTVAPGRTECICQKGYVGDGLT 360
Query: 314 C 314
C
Sbjct: 361 C 361
Score = 51.6 bits (118), Expect = 1e-05
Identities = 48/185 (25%), Positives = 71/185 (38%), Gaps = 20/185 (10%)
Query: 18 LCVGERC---VDTDQGFRCERCPGSQTSDGQTC---RTACSANPCFGGRVPCQDLPDGRY 71
LCV C +D+D C S G+ C +AC F + +G
Sbjct: 793 LCVHGTCNNRIDSDGACLTGTCRDG--SAGRLCDKQTSACGPYVQFCHIHATCEYSNGTA 850
Query: 72 QCGKCPSGFHGNGVECYRIS-CRANT---CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ 127
C C +G+ G+G C + C T C + C +T G C G+ G+GR C
Sbjct: 851 SC-ICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCS 909
Query: 128 HVCDAQKP----CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDL 182
+ + P C C+ ECE C G++ NG C + C + C L
Sbjct: 910 EINNCLLPSAGGCHDNASCLYVGPG-QNECE-CKKGFRGNGIDCEPITSCLEQTGKCHPL 967
Query: 183 VSCRN 187
SC++
Sbjct: 968 ASCQS 972
Score = 47.2 bits (107), Expect = 2e-04
Identities = 44/160 (27%), Positives = 63/160 (39%), Gaps = 22/160 (13%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C + G CE C G +C + C+ C G C DG C +C S + G
Sbjct: 138 CQEGFGGTACETCADDNLF-GPSCSSVCN---CVHG--VCNSGLDGDGTC-ECYSAYTGP 190
Query: 84 GVECYRISCRANTCFQGVSCE---ETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
+ C A C + C E + +C C Y GDG+ C D PC R +
Sbjct: 191 KCDKPIPECAALLCPENSRCSPSTEDENKLEC-KCLPNYRGDGKYC----DPINPCLR-K 244
Query: 141 RCMPKSTSPY-----YECEGCPSGYQWNGYTCVDMDECDL 175
C P + Y + C C GY+ +G C+ +D C +
Sbjct: 245 ICHPHAHCTYLGPNRHSCT-CQEGYRGDGQVCLPVDPCQI 283
Score = 47.2 bits (107), Expect = 2e-04
Identities = 49/172 (28%), Positives = 68/172 (39%), Gaps = 24/172 (13%)
Query: 23 RCVDTDQGFRCERC-PGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
+C G CE C PG D C CS + G+ C D G QC C +G+
Sbjct: 1987 KCNTGFNGTACEMCWPGRFGPDCLPC--GCSDH----GQ--CDDGITGSGQC-LCETGWT 2037
Query: 82 GNGVECYRISCRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKP-C 136
G + + T C +C+E C C Y GDG C V C C
Sbjct: 2038 GPSCDTQAVLPAVCTPPCSAHATCKENN---TC-ECNLDYEGDGITCTVVDFCKQDNGGC 2093
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC--DLIRPCDDLVSCR 186
+ RC K T C C GY+ +G++C ++D C L C + +C+
Sbjct: 2094 AKVARCSQKGTK--VSCS-CQKGYKGDGHSCTEIDPCADGLNGGCHEHATCK 2142
Score = 42.3 bits (95), Expect = 0.007
Identities = 46/177 (25%), Positives = 64/177 (36%), Gaps = 45/177 (25%)
Query: 92 CRANTCFQGVSCE---ETQYGPKC--------GSCPTGYVGDGR-QCQ-----HVCDAQ- 133
C+ NT F G +CE ++GP C G C G G G+ C+ CD Q
Sbjct: 1986 CKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQA 2045
Query: 134 -------KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIR-PCDDLVSC 185
PC C +T CE C Y+ +G TC +D C C + C
Sbjct: 2046 VLPAVCTPPCSAHATCKENNT-----CE-CNLDYEGDGITCTVVDFCKQDNGGCAKVARC 2099
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADG-RANCPRGRLCVNT 241
+ +G++G G+ C ++D CADG C C T
Sbjct: 2100 SQK-------GTKVSCSCQKGYKGDGHS-----CTEIDPCADGLNGGCHEHATCKMT 2144
Score = 37.1 bits (82), Expect = 0.25
Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 8/101 (7%)
Query: 33 CERCPGSQTSDGQTCRTACSANPCFGG--RVPCQDLPDGRYQCGKCPSGFHGNGVECYRI 90
CE C DG TC GG +V + C C G+ G+G C I
Sbjct: 2067 CE-CNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCS-CQKGYKGDGHSCTEI 2124
Query: 91 SCRANT----CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ 127
A+ C + +C+ T G C + YVGDG C+
Sbjct: 2125 DPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCE 2165
Score = 33.1 bits (72), Expect = 4.0
Identities = 18/34 (52%), Positives = 18/34 (52%), Gaps = 5/34 (14%)
Query: 285 PSYCRRFNAVC---GFG-QKCVCNTGWTGNGTVC 314
P C R NA C G G CVC GWTGNG C
Sbjct: 876 PGGCSR-NAECIKTGTGTHTCVCQQGWTGNGRDC 908
>AB052958-1|BAC15608.1| 2551|Homo sapiens FELE-2 protein.
Length = 2551
Score = 62.5 bits (145), Expect = 6e-09
Identities = 45/160 (28%), Positives = 62/160 (38%), Gaps = 17/160 (10%)
Query: 20 VGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
+G+ D D G+R C + T D C C + C DG C KC +G
Sbjct: 1411 LGDGSCDCDVGWRGVHCDNATTEDN--CNGTCHTS------ANCLTNSDGTASC-KCAAG 1461
Query: 80 FHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--C-DAQ 133
F GNG C I+ C + C C+ T G + +C GY GDG C + C +
Sbjct: 1462 FQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENH 1521
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC 173
C + C T P C Y +G C ++ C
Sbjct: 1522 GGCDKNAEC--TQTGPNQAACNCLPAYTGDGKVCTLINVC 1559
Score = 54.4 bits (125), Expect = 2e-06
Identities = 38/121 (31%), Positives = 50/121 (41%), Gaps = 8/121 (6%)
Query: 13 VTPFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSAN-PCFGG---RVPCQDLPD 68
+TP C+ T G C T +G+ C + P GG C +
Sbjct: 874 LTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGP 933
Query: 69 GRYQCGKCPSGFHGNGVECYRI-SCRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQ 125
G+ +C +C GF GNG++C I SC T C SC+ T G C GY GDG
Sbjct: 934 GQNEC-ECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGDGFL 992
Query: 126 C 126
C
Sbjct: 993 C 993
Score = 52.0 bits (119), Expect = 8e-06
Identities = 75/308 (24%), Positives = 111/308 (36%), Gaps = 54/308 (17%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHG 82
+CV T C C G Q C + N CFG + C D +G C +C GF G
Sbjct: 1326 KCVRTVITREC--CAGFFGPQCQPC-PGNAQNVCFGNGI-CLDGVNGTGVC-ECGEGFSG 1380
Query: 83 NGVE-C----YRISC-RANTCFQGVSCEETQYGPKCGSCPTGYVG---DGRQCQHVCDAQ 133
E C Y I C +A +C G C + G C G+ G D + C+
Sbjct: 1381 TACETCTEGKYGIHCDQACSCVHG-RCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGT 1439
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIR-PCDDLVSCRNEEXXX 192
C C+ S C+ C +G+Q NG C ++ C++ C C+
Sbjct: 1440 --CHTSANCLTNSDGTA-SCK-CAAGFQGNGTICTAINACEISNGGCSAKADCKR----- 1490
Query: 193 XXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSL 252
G+ G G C++++ C + C + C T P+
Sbjct: 1491 -TTPGRRVCTCKAGYTGDGIV-----CLEINPCLENHGGCDKNAECTQTG--PN------ 1536
Query: 253 QGSYICVPCGGHYYVNTTRPCFDPDSLVKRC--DPSYCRRFNAVCGF-GQ---KCVCNTG 306
Q + C+P Y + C +L+ C C F A+C GQ C C
Sbjct: 1537 QAACNCLPA----YTGDGKVC----TLINVCLTKNGGCSEF-AICNHTGQVERTCTCKPN 1587
Query: 307 WTGNGTVC 314
+ G+G C
Sbjct: 1588 YIGDGFTC 1595
Score = 51.6 bits (118), Expect = 1e-05
Identities = 81/301 (26%), Positives = 108/301 (35%), Gaps = 56/301 (18%)
Query: 32 RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS 91
RC CPG D C + +PC GR C + +G C C GF G E +
Sbjct: 99 RC--CPGRWGPDCIECPGG-AGSPC-NGRGSCAEGMEGNGTCS-CQEGFGGTACE----T 149
Query: 92 CRANTCFQGVSCEETQYGPKCGSCPTGYVGDGR-QCQHV-----CDAQKP------CGRE 139
C + F G SC G C +G GDG +C CD P C
Sbjct: 150 CADDNLF-GPSCSSV-CNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPEN 207
Query: 140 RRCMPKSTSPY-YECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXX 198
RC P + EC+ C Y+ +G CD I PC + C
Sbjct: 208 SRCSPSTEDENKLECK-CLPNYRGDG------KYCDPINPCLRKI-CHPHAHCTYLGPNR 259
Query: 199 XXXXXSQGWRGTGNERRREHCVDVDECADGRANCP-RGRLCVNTPQYPSNPVSSLQGSYI 257
+G+RG G + C+ VD C NCP + +C +Y G
Sbjct: 260 HSCTCQEGYRGDG-----QVCLPVDPCQINFGNCPTKSTVC----KYDG------PGQSH 304
Query: 258 CVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQ-KCVCNTGWTGNGTV 313
C C HY + K +P C R NA C G+ +C+C G+ G+G
Sbjct: 305 C-ECKEHYQNFVPGVGCSMTDICKSDNP--CHR-NANCTTVAPGRTECICQKGYVGDGLT 360
Query: 314 C 314
C
Sbjct: 361 C 361
Score = 51.6 bits (118), Expect = 1e-05
Identities = 48/185 (25%), Positives = 71/185 (38%), Gaps = 20/185 (10%)
Query: 18 LCVGERC---VDTDQGFRCERCPGSQTSDGQTC---RTACSANPCFGGRVPCQDLPDGRY 71
LCV C +D+D C S G+ C +AC F + +G
Sbjct: 793 LCVHGTCNNRIDSDGACLTGTCRDG--SAGRLCDKQTSACGPYVQFCHIHATCEYSNGTA 850
Query: 72 QCGKCPSGFHGNGVECYRIS-CRANT---CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ 127
C C +G+ G+G C + C T C + C +T G C G+ G+GR C
Sbjct: 851 SC-ICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCS 909
Query: 128 HVCDAQKP----CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDL 182
+ + P C C+ ECE C G++ NG C + C + C L
Sbjct: 910 EINNCLLPSAGGCHDNASCLYVGPG-QNECE-CKKGFRGNGIDCEPITSCLEQTGKCHPL 967
Query: 183 VSCRN 187
SC++
Sbjct: 968 ASCQS 972
Score = 47.2 bits (107), Expect = 2e-04
Identities = 44/160 (27%), Positives = 63/160 (39%), Gaps = 22/160 (13%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C + G CE C G +C + C+ C G C DG C +C S + G
Sbjct: 138 CQEGFGGTACETCADDNLF-GPSCSSVCN---CVHG--VCNSGLDGDGTC-ECYSAYTGP 190
Query: 84 GVECYRISCRANTCFQGVSCE---ETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
+ C A C + C E + +C C Y GDG+ C D PC R +
Sbjct: 191 KCDKPIPECAALLCPENSRCSPSTEDENKLEC-KCLPNYRGDGKYC----DPINPCLR-K 244
Query: 141 RCMPKSTSPY-----YECEGCPSGYQWNGYTCVDMDECDL 175
C P + Y + C C GY+ +G C+ +D C +
Sbjct: 245 ICHPHAHCTYLGPNRHSCT-CQEGYRGDGQVCLPVDPCQI 283
Score = 47.2 bits (107), Expect = 2e-04
Identities = 49/172 (28%), Positives = 68/172 (39%), Gaps = 24/172 (13%)
Query: 23 RCVDTDQGFRCERC-PGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
+C G CE C PG D C CS + G+ C D G QC C +G+
Sbjct: 1987 KCNTGFNGTACEMCWPGRFGPDCLPC--GCSDH----GQ--CDDGITGSGQC-LCETGWT 2037
Query: 82 GNGVECYRISCRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKP-C 136
G + + T C +C+E C C Y GDG C V C C
Sbjct: 2038 GPSCDTQAVLPAVCTPPCSAHATCKENN---TC-ECNLDYEGDGITCTVVDFCKQDNGGC 2093
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC--DLIRPCDDLVSCR 186
+ RC K T C C GY+ +G++C ++D C L C + +C+
Sbjct: 2094 AKVARCSQKGTK--VSCS-CQKGYKGDGHSCTEIDPCADGLNGGCHEHATCK 2142
Score = 42.3 bits (95), Expect = 0.007
Identities = 46/177 (25%), Positives = 64/177 (36%), Gaps = 45/177 (25%)
Query: 92 CRANTCFQGVSCE---ETQYGPKC--------GSCPTGYVGDGR-QCQ-----HVCDAQ- 133
C+ NT F G +CE ++GP C G C G G G+ C+ CD Q
Sbjct: 1986 CKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQA 2045
Query: 134 -------KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIR-PCDDLVSC 185
PC C +T CE C Y+ +G TC +D C C + C
Sbjct: 2046 VLPAVCTPPCSAHATCKENNT-----CE-CNLDYEGDGITCTVVDFCKQDNGGCAKVARC 2099
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADG-RANCPRGRLCVNT 241
+ +G++G G+ C ++D CADG C C T
Sbjct: 2100 SQK-------GTKVSCSCQKGYKGDGHS-----CTEIDPCADGLNGGCHEHATCKMT 2144
Score = 37.1 bits (82), Expect = 0.25
Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 8/101 (7%)
Query: 33 CERCPGSQTSDGQTCRTACSANPCFGG--RVPCQDLPDGRYQCGKCPSGFHGNGVECYRI 90
CE C DG TC GG +V + C C G+ G+G C I
Sbjct: 2067 CE-CNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCS-CQKGYKGDGHSCTEI 2124
Query: 91 SCRANT----CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ 127
A+ C + +C+ T G C + YVGDG C+
Sbjct: 2125 DPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCE 2165
Score = 33.1 bits (72), Expect = 4.0
Identities = 18/34 (52%), Positives = 18/34 (52%), Gaps = 5/34 (14%)
Query: 285 PSYCRRFNAVC---GFG-QKCVCNTGWTGNGTVC 314
P C R NA C G G CVC GWTGNG C
Sbjct: 876 PGGCSR-NAECIKTGTGTHTCVCQQGWTGNGRDC 908
>AK123000-1|BAC85516.1| 1176|Homo sapiens 3 (HIVEP3). protein.
Length = 1176
Score = 61.7 bits (143), Expect = 1e-08
Identities = 49/159 (30%), Positives = 68/159 (42%), Gaps = 14/159 (8%)
Query: 30 GFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYR 89
GFRC PG Q + C++ PC G C++L D RY+C CP G+ G E
Sbjct: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHG-ATCRNLAD-RYEC-HCPLGYAGVTCETEV 147
Query: 90 ISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKST 147
C + C G SC + +C C GY G +CQ D +PC C
Sbjct: 148 DECASAPCLHGASCLDGVGSFRC-VCAPGY--GGTRCQLDLDECQSQPCAHGGTCHDLVN 204
Query: 148 SPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSC 185
+ C+ +GY+ G C ++ EC PC+ SC
Sbjct: 205 G--FRCDCAGTGYE--GTHCEREVLEC-ASAPCEHNASC 238
Score = 61.3 bits (142), Expect = 1e-08
Identities = 43/132 (32%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Query: 30 GFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYR 89
GF C PG + +D C++ PC G CQDLP+G +QC CP G+ G E
Sbjct: 303 GFLCHCPPGFEGADCGVEVDECASRPCLNGG-HCQDLPNG-FQC-HCPDGYAGPTCEEDV 359
Query: 90 ISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMP--KST 147
C ++ C G +C +T G C CP + G Q C C+P +S
Sbjct: 360 DECLSDPCLHGGTCSDTVAGYIC-RCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESG 418
Query: 148 SPYYECEGCPSG 159
Y C CP G
Sbjct: 419 VHSYVCH-CPPG 429
Score = 55.6 bits (128), Expect = 7e-07
Identities = 48/163 (29%), Positives = 67/163 (41%), Gaps = 16/163 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C + + C CP G TC T C++ PC G C D G ++C C
Sbjct: 120 GATCRNLADRYECH-CPLGYA--GVTCETEVDECASAPCLHG-ASCLD-GVGSFRC-VCA 173
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCG 137
G+ G + C++ C G +C + G +C TGY G + + + A PC
Sbjct: 174 PGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCE 233
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPC 179
C+ S + C C GY +G C VD DEC PC
Sbjct: 234 HNASCLEGLGS--FRCL-CWPGY--SGELCEVDEDEC-ASSPC 270
Score = 43.2 bits (97), Expect = 0.004
Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 4/78 (5%)
Query: 6 MGDAGSMVTPFKLCVGE-RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQ 64
+G G+ V C+ + C D F C PG + + C + PC GR C
Sbjct: 1052 LGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR--CH 1109
Query: 65 DLPDGRYQCGKCPSGFHG 82
PDGR++C +CP GF G
Sbjct: 1110 THPDGRFEC-RCPPGFGG 1126
Score = 41.9 bits (94), Expect = 0.009
Identities = 46/171 (26%), Positives = 60/171 (35%), Gaps = 29/171 (16%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPC-FGGRVPCQDLP--------------D 68
C++ FRC PG + C+++PC GGR + P
Sbjct: 238 CLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFS 297
Query: 69 GRYQCG---KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQ 125
R+ G CP GF G C + C G C++ G +C CP GY G
Sbjct: 298 FRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQC-HCPDGYAGP--T 354
Query: 126 CQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
C+ D PC C T Y C CP W G C V + C
Sbjct: 355 CEEDVDECLSDPCLHGGTC--SDTVAGYICR-CPE--TWGGRDCSVQLTGC 400
>D89629-1|BAB46925.1| 815|Homo sapiens cerebral protein-12 protein.
Length = 815
Score = 61.3 bits (142), Expect = 1e-08
Identities = 37/100 (37%), Positives = 48/100 (48%), Gaps = 18/100 (18%)
Query: 218 HCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPD 277
+C D+DECA+GR C +CVNTP GS++C+ C Y C + D
Sbjct: 436 YCEDIDECAEGRHYCRENTMCVNTP-----------GSFMCI-CKTGYIRIDDYSCTEHD 483
Query: 278 SLV---KRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
+ CD + FN V G CVC G+TGNGT C
Sbjct: 484 ECITNQHNCDEN-ALCFNTV--GGHNCVCKPGYTGNGTTC 520
Score = 51.6 bits (118), Expect = 1e-05
Identities = 42/149 (28%), Positives = 57/149 (38%), Gaps = 21/149 (14%)
Query: 95 NTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECE 154
+ C + C T G C C GY G+G C+ C + C C+ + C
Sbjct: 490 HNCDENALCFNTVGGHNC-VCKPGYTGNGTTCKAFC--KDGCRNGGACIAANV-----C- 540
Query: 155 GCPSGYQWNGYTC-VDMDEC-DLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGN 212
CP G+ G +C D+DEC D CD +C N G+ G
Sbjct: 541 ACPQGF--TGPSCETDIDECSDGFVQCDSRANCIN-------LPGWYHCECRDGYHDNGM 591
Query: 213 -ERRREHCVDVDECADGRANCPRGRLCVN 240
E C D+DEC GR +C +C N
Sbjct: 592 FSPSGESCEDIDECGTGRHSCANDTICFN 620
>D83018-1|BAA11681.1| 816|Homo sapiens nel-related protein 2
protein.
Length = 816
Score = 61.3 bits (142), Expect = 1e-08
Identities = 37/100 (37%), Positives = 48/100 (48%), Gaps = 18/100 (18%)
Query: 218 HCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPD 277
+C D+DECA+GR C +CVNTP GS++C+ C Y C + D
Sbjct: 437 YCEDIDECAEGRHYCRENTMCVNTP-----------GSFMCI-CKTGYIRIDDYSCTEHD 484
Query: 278 SLV---KRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
+ CD + FN V G CVC G+TGNGT C
Sbjct: 485 ECITNQHNCDEN-ALCFNTV--GGHNCVCKPGYTGNGTTC 521
Score = 51.6 bits (118), Expect = 1e-05
Identities = 42/149 (28%), Positives = 57/149 (38%), Gaps = 21/149 (14%)
Query: 95 NTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECE 154
+ C + C T G C C GY G+G C+ C + C C+ + C
Sbjct: 491 HNCDENALCFNTVGGHNC-VCKPGYTGNGTTCKAFC--KDGCRNGGACIAANV-----C- 541
Query: 155 GCPSGYQWNGYTC-VDMDEC-DLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGN 212
CP G+ G +C D+DEC D CD +C N G+ G
Sbjct: 542 ACPQGF--TGPSCETDIDECSDGFVQCDSRANCIN-------LPGWYHCECRDGYHDNGM 592
Query: 213 -ERRREHCVDVDECADGRANCPRGRLCVN 240
E C D+DEC GR +C +C N
Sbjct: 593 FSPSGESCEDIDECGTGRHSCANDTICFN 621
>BC020544-1|AAH20544.1| 816|Homo sapiens NELL2 protein protein.
Length = 816
Score = 61.3 bits (142), Expect = 1e-08
Identities = 37/100 (37%), Positives = 48/100 (48%), Gaps = 18/100 (18%)
Query: 218 HCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPD 277
+C D+DECA+GR C +CVNTP GS++C+ C Y C + D
Sbjct: 437 YCEDIDECAEGRHYCRENTMCVNTP-----------GSFMCI-CKTGYIRIDDYSCTEHD 484
Query: 278 SLV---KRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
+ CD + FN V G CVC G+TGNGT C
Sbjct: 485 ECITNQHNCDEN-ALCFNTV--GGHNCVCKPGYTGNGTTC 521
Score = 51.6 bits (118), Expect = 1e-05
Identities = 42/149 (28%), Positives = 57/149 (38%), Gaps = 21/149 (14%)
Query: 95 NTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECE 154
+ C + C T G C C GY G+G C+ C + C C+ + C
Sbjct: 491 HNCDENALCFNTVGGHNC-VCKPGYTGNGTTCKAFC--KDGCRNGGACIAANV-----C- 541
Query: 155 GCPSGYQWNGYTC-VDMDEC-DLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGN 212
CP G+ G +C D+DEC D CD +C N G+ G
Sbjct: 542 ACPQGF--TGPSCETDIDECSDGFVQCDSRANCIN-------LPGWYHCECRDGYHDNGM 592
Query: 213 -ERRREHCVDVDECADGRANCPRGRLCVN 240
E C D+DEC GR +C +C N
Sbjct: 593 FSPSGESCEDIDECGTGRHSCANDTICFN 621
>AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2
precursor protein.
Length = 1285
Score = 61.3 bits (142), Expect = 1e-08
Identities = 43/132 (32%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Query: 30 GFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYR 89
GF C PG + +D C++ PC G CQDLP+G +QC CP G+ G E
Sbjct: 303 GFLCHCPPGFEGADCGVEVDECASRPCLNGG-HCQDLPNG-FQC-HCPDGYAGPTCEEDV 359
Query: 90 ISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMP--KST 147
C ++ C G +C +T G C CP + G Q C C+P +S
Sbjct: 360 DECLSDPCLHGGTCSDTVAGYIC-RCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESG 418
Query: 148 SPYYECEGCPSG 159
Y C CP G
Sbjct: 419 VHSYVCH-CPPG 429
Score = 60.5 bits (140), Expect = 2e-08
Identities = 49/159 (30%), Positives = 68/159 (42%), Gaps = 14/159 (8%)
Query: 30 GFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYR 89
GFRC PG Q + C++ PC G C++L D RY+C CP G+ G E
Sbjct: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHG-ATCRNLAD-RYEC-HCPLGYAGVTCEMEV 147
Query: 90 ISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKST 147
C + C G SC + +C C GY G +CQ D +PC C
Sbjct: 148 DECASAPCLHGGSCLDGVGSFRC-VCAPGY--GGTRCQLDLDECQSQPCAHGGTCHDLVN 204
Query: 148 SPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSC 185
+ C+ +GY+ G C ++ EC PC+ SC
Sbjct: 205 G--FRCDCAGTGYE--GTHCEREVLEC-ASAPCEHNASC 238
Score = 53.2 bits (122), Expect = 4e-06
Identities = 44/136 (32%), Positives = 56/136 (41%), Gaps = 10/136 (7%)
Query: 6 MGDAGSMVTPFKLCVGE-RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQ 64
+G G+ V C+ + C D F C PG + + C + PC GR C
Sbjct: 1052 LGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR--CH 1109
Query: 65 DLPDGRYQCGKCPSGFHGNGVECYRIS--CRAN-TCFQGVSCEETQYGPKCGSCPTGYVG 121
PDGR++C +CP GF G S C N TC G CE C SC G G
Sbjct: 1110 THPDGRFEC-RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANC-SCLEGLAG 1167
Query: 122 DGRQCQHV-CDAQKPC 136
Q + C+A PC
Sbjct: 1168 QRCQVPTLPCEA-NPC 1182
Score = 52.4 bits (120), Expect = 6e-06
Identities = 47/163 (28%), Positives = 66/163 (40%), Gaps = 16/163 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C + + C CP G TC C++ PC G C D G ++C C
Sbjct: 120 GATCRNLADRYECH-CPLGYA--GVTCEMEVDECASAPCLHGG-SCLD-GVGSFRC-VCA 173
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCG 137
G+ G + C++ C G +C + G +C TGY G + + + A PC
Sbjct: 174 PGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCE 233
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPC 179
C+ S + C C GY +G C VD DEC PC
Sbjct: 234 HNASCLEGLGS--FRCL-CWPGY--SGELCEVDEDEC-ASSPC 270
Score = 41.9 bits (94), Expect = 0.009
Identities = 46/171 (26%), Positives = 60/171 (35%), Gaps = 29/171 (16%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPC-FGGRVPCQDLP--------------D 68
C++ FRC PG + C+++PC GGR + P
Sbjct: 238 CLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFS 297
Query: 69 GRYQCG---KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQ 125
R+ G CP GF G C + C G C++ G +C CP GY G
Sbjct: 298 FRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQC-HCPDGYAGP--T 354
Query: 126 CQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
C+ D PC C T Y C CP W G C V + C
Sbjct: 355 CEEDVDECLSDPCLHGGTC--SDTVAGYICR-CPE--TWGGRDCSVQLTGC 400
>AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1285
Score = 61.3 bits (142), Expect = 1e-08
Identities = 43/132 (32%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Query: 30 GFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYR 89
GF C PG + +D C++ PC G CQDLP+G +QC CP G+ G E
Sbjct: 303 GFLCHCPPGFEGADCGVEVDECASRPCLNGG-HCQDLPNG-FQC-HCPDGYAGPTCEEDV 359
Query: 90 ISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMP--KST 147
C ++ C G +C +T G C CP + G Q C C+P +S
Sbjct: 360 DECLSDPCLHGGTCSDTVAGYIC-RCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESG 418
Query: 148 SPYYECEGCPSG 159
Y C CP G
Sbjct: 419 VHSYVCH-CPPG 429
Score = 60.5 bits (140), Expect = 2e-08
Identities = 49/159 (30%), Positives = 68/159 (42%), Gaps = 14/159 (8%)
Query: 30 GFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYR 89
GFRC PG Q + C++ PC G C++L D RY+C CP G+ G E
Sbjct: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHG-ATCRNLAD-RYEC-HCPLGYAGVTCEMEV 147
Query: 90 ISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKST 147
C + C G SC + +C C GY G +CQ D +PC C
Sbjct: 148 DECASAPCLHGGSCLDGVGSFRC-VCAPGY--GGTRCQLDLDECQSQPCAHGGTCHDLVN 204
Query: 148 SPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSC 185
+ C+ +GY+ G C ++ EC PC+ SC
Sbjct: 205 G--FRCDCAGTGYE--GTHCEREVLEC-ASAPCEHNASC 238
Score = 53.2 bits (122), Expect = 4e-06
Identities = 44/136 (32%), Positives = 56/136 (41%), Gaps = 10/136 (7%)
Query: 6 MGDAGSMVTPFKLCVGE-RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQ 64
+G G+ V C+ + C D F C PG + + C + PC GR C
Sbjct: 1052 LGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR--CH 1109
Query: 65 DLPDGRYQCGKCPSGFHGNGVECYRIS--CRAN-TCFQGVSCEETQYGPKCGSCPTGYVG 121
PDGR++C +CP GF G S C N TC G CE C SC G G
Sbjct: 1110 THPDGRFEC-RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANC-SCLEGLAG 1167
Query: 122 DGRQCQHV-CDAQKPC 136
Q + C+A PC
Sbjct: 1168 QRCQVPTLPCEA-NPC 1182
Score = 52.4 bits (120), Expect = 6e-06
Identities = 47/163 (28%), Positives = 66/163 (40%), Gaps = 16/163 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C + + C CP G TC C++ PC G C D G ++C C
Sbjct: 120 GATCRNLADRYECH-CPLGYA--GVTCEMEVDECASAPCLHGG-SCLD-GVGSFRC-VCA 173
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCG 137
G+ G + C++ C G +C + G +C TGY G + + + A PC
Sbjct: 174 PGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCE 233
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPC 179
C+ S + C C GY +G C VD DEC PC
Sbjct: 234 HNASCLEGLGS--FRCL-CWPGY--SGELCEVDEDEC-ASSPC 270
Score = 41.9 bits (94), Expect = 0.009
Identities = 46/171 (26%), Positives = 60/171 (35%), Gaps = 29/171 (16%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPC-FGGRVPCQDLP--------------D 68
C++ FRC PG + C+++PC GGR + P
Sbjct: 238 CLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFS 297
Query: 69 GRYQCG---KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQ 125
R+ G CP GF G C + C G C++ G +C CP GY G
Sbjct: 298 FRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQC-HCPDGYAGP--T 354
Query: 126 CQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
C+ D PC C T Y C CP W G C V + C
Sbjct: 355 CEEDVDECLSDPCLHGGTC--SDTVAGYICR-CPE--TWGGRDCSVQLTGC 400
>AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1176
Score = 61.3 bits (142), Expect = 1e-08
Identities = 43/132 (32%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Query: 30 GFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYR 89
GF C PG + +D C++ PC G CQDLP+G +QC CP G+ G E
Sbjct: 303 GFLCHCPPGFEGADCGVEVDECASRPCLNGG-HCQDLPNG-FQC-HCPDGYAGPTCEEDV 359
Query: 90 ISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMP--KST 147
C ++ C G +C +T G C CP + G Q C C+P +S
Sbjct: 360 DECLSDPCLHGGTCSDTVAGYIC-RCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESG 418
Query: 148 SPYYECEGCPSG 159
Y C CP G
Sbjct: 419 VHSYVCH-CPPG 429
Score = 60.5 bits (140), Expect = 2e-08
Identities = 49/159 (30%), Positives = 68/159 (42%), Gaps = 14/159 (8%)
Query: 30 GFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYR 89
GFRC PG Q + C++ PC G C++L D RY+C CP G+ G E
Sbjct: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHG-ATCRNLAD-RYEC-HCPLGYAGVTCEMEV 147
Query: 90 ISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKST 147
C + C G SC + +C C GY G +CQ D +PC C
Sbjct: 148 DECASAPCLHGGSCLDGVGSFRC-VCAPGY--GGTRCQLDLDECQSQPCAHGGTCHDLVN 204
Query: 148 SPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSC 185
+ C+ +GY+ G C ++ EC PC+ SC
Sbjct: 205 G--FRCDCAGTGYE--GTHCEREVLEC-ASAPCEHNASC 238
Score = 52.4 bits (120), Expect = 6e-06
Identities = 47/163 (28%), Positives = 66/163 (40%), Gaps = 16/163 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C + + C CP G TC C++ PC G C D G ++C C
Sbjct: 120 GATCRNLADRYECH-CPLGYA--GVTCEMEVDECASAPCLHGG-SCLD-GVGSFRC-VCA 173
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCG 137
G+ G + C++ C G +C + G +C TGY G + + + A PC
Sbjct: 174 PGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCE 233
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPC 179
C+ S + C C GY +G C VD DEC PC
Sbjct: 234 HNASCLEGLGS--FRCL-CWPGY--SGELCEVDEDEC-ASSPC 270
Score = 43.2 bits (97), Expect = 0.004
Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 4/78 (5%)
Query: 6 MGDAGSMVTPFKLCVGE-RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQ 64
+G G+ V C+ + C D F C PG + + C + PC GR C
Sbjct: 1052 LGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR--CH 1109
Query: 65 DLPDGRYQCGKCPSGFHG 82
PDGR++C +CP GF G
Sbjct: 1110 THPDGRFEC-RCPPGFGG 1126
Score = 41.9 bits (94), Expect = 0.009
Identities = 46/171 (26%), Positives = 60/171 (35%), Gaps = 29/171 (16%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPC-FGGRVPCQDLP--------------D 68
C++ FRC PG + C+++PC GGR + P
Sbjct: 238 CLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFS 297
Query: 69 GRYQCG---KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQ 125
R+ G CP GF G C + C G C++ G +C CP GY G
Sbjct: 298 FRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQC-HCPDGYAGP--T 354
Query: 126 CQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
C+ D PC C T Y C CP W G C V + C
Sbjct: 355 CEEDVDECLSDPCLHGGTC--SDTVAGYICR-CPE--TWGGRDCSVQLTGC 400
>AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1285
Score = 61.3 bits (142), Expect = 1e-08
Identities = 43/132 (32%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Query: 30 GFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYR 89
GF C PG + +D C++ PC G CQDLP+G +QC CP G+ G E
Sbjct: 303 GFLCHCPPGFEGADCGVEVDECASRPCLNGG-HCQDLPNG-FQC-HCPDGYAGPTCEEDV 359
Query: 90 ISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMP--KST 147
C ++ C G +C +T G C CP + G Q C C+P +S
Sbjct: 360 DECLSDPCLHGGTCSDTVAGYIC-RCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESG 418
Query: 148 SPYYECEGCPSG 159
Y C CP G
Sbjct: 419 VHSYVCH-CPPG 429
Score = 60.5 bits (140), Expect = 2e-08
Identities = 49/159 (30%), Positives = 68/159 (42%), Gaps = 14/159 (8%)
Query: 30 GFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYR 89
GFRC PG Q + C++ PC G C++L D RY+C CP G+ G E
Sbjct: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHG-ATCRNLAD-RYEC-HCPLGYAGVTCEMEV 147
Query: 90 ISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKST 147
C + C G SC + +C C GY G +CQ D +PC C
Sbjct: 148 DECASAPCLHGGSCLDGVGSFRC-VCAPGY--GGTRCQLDLDECQSQPCAHGGTCHDLVN 204
Query: 148 SPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSC 185
+ C+ +GY+ G C ++ EC PC+ SC
Sbjct: 205 G--FRCDCAGTGYE--GTHCEREVLEC-ASAPCEHNASC 238
Score = 53.2 bits (122), Expect = 4e-06
Identities = 44/136 (32%), Positives = 56/136 (41%), Gaps = 10/136 (7%)
Query: 6 MGDAGSMVTPFKLCVGE-RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQ 64
+G G+ V C+ + C D F C PG + + C + PC GR C
Sbjct: 1052 LGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR--CH 1109
Query: 65 DLPDGRYQCGKCPSGFHGNGVECYRIS--CRAN-TCFQGVSCEETQYGPKCGSCPTGYVG 121
PDGR++C +CP GF G S C N TC G CE C SC G G
Sbjct: 1110 THPDGRFEC-RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANC-SCLEGLAG 1167
Query: 122 DGRQCQHV-CDAQKPC 136
Q + C+A PC
Sbjct: 1168 QRCQVPTLPCEA-NPC 1182
Score = 52.4 bits (120), Expect = 6e-06
Identities = 47/163 (28%), Positives = 66/163 (40%), Gaps = 16/163 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C + + C CP G TC C++ PC G C D G ++C C
Sbjct: 120 GATCRNLADRYECH-CPLGYA--GVTCEMEVDECASAPCLHGG-SCLD-GVGSFRC-VCA 173
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCG 137
G+ G + C++ C G +C + G +C TGY G + + + A PC
Sbjct: 174 PGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCE 233
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPC 179
C+ S + C C GY +G C VD DEC PC
Sbjct: 234 HNASCLEGLGS--FRCL-CWPGY--SGELCEVDEDEC-ASSPC 270
Score = 41.9 bits (94), Expect = 0.009
Identities = 46/171 (26%), Positives = 60/171 (35%), Gaps = 29/171 (16%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPC-FGGRVPCQDLP--------------D 68
C++ FRC PG + C+++PC GGR + P
Sbjct: 238 CLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFS 297
Query: 69 GRYQCG---KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQ 125
R+ G CP GF G C + C G C++ G +C CP GY G
Sbjct: 298 FRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQC-HCPDGYAGP--T 354
Query: 126 CQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
C+ D PC C T Y C CP W G C V + C
Sbjct: 355 CEEDVDECLSDPCLHGGTC--SDTVAGYICR-CPE--TWGGRDCSVQLTGC 400
>AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1176
Score = 61.3 bits (142), Expect = 1e-08
Identities = 43/132 (32%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Query: 30 GFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYR 89
GF C PG + +D C++ PC G CQDLP+G +QC CP G+ G E
Sbjct: 303 GFLCHCPPGFEGADCGVEVDECASRPCLNGG-HCQDLPNG-FQC-HCPDGYAGPTCEEDV 359
Query: 90 ISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMP--KST 147
C ++ C G +C +T G C CP + G Q C C+P +S
Sbjct: 360 DECLSDPCLHGGTCSDTVAGYIC-RCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESG 418
Query: 148 SPYYECEGCPSG 159
Y C CP G
Sbjct: 419 VHSYVCH-CPPG 429
Score = 60.5 bits (140), Expect = 2e-08
Identities = 49/159 (30%), Positives = 68/159 (42%), Gaps = 14/159 (8%)
Query: 30 GFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYR 89
GFRC PG Q + C++ PC G C++L D RY+C CP G+ G E
Sbjct: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHG-ATCRNLAD-RYEC-HCPLGYAGVTCEMEV 147
Query: 90 ISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKST 147
C + C G SC + +C C GY G +CQ D +PC C
Sbjct: 148 DECASAPCLHGGSCLDGVGSFRC-VCAPGY--GGTRCQLDLDECQSQPCAHGGTCHDLVN 204
Query: 148 SPYYECEGCPSGYQWNGYTCV-DMDECDLIRPCDDLVSC 185
+ C+ +GY+ G C ++ EC PC+ SC
Sbjct: 205 G--FRCDCAGTGYE--GTHCEREVLEC-ASAPCEHNASC 238
Score = 52.4 bits (120), Expect = 6e-06
Identities = 47/163 (28%), Positives = 66/163 (40%), Gaps = 16/163 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA---CSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C + + C CP G TC C++ PC G C D G ++C C
Sbjct: 120 GATCRNLADRYECH-CPLGYA--GVTCEMEVDECASAPCLHGG-SCLD-GVGSFRC-VCA 173
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCG 137
G+ G + C++ C G +C + G +C TGY G + + + A PC
Sbjct: 174 PGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCE 233
Query: 138 RERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPC 179
C+ S + C C GY +G C VD DEC PC
Sbjct: 234 HNASCLEGLGS--FRCL-CWPGY--SGELCEVDEDEC-ASSPC 270
Score = 43.2 bits (97), Expect = 0.004
Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 4/78 (5%)
Query: 6 MGDAGSMVTPFKLCVGE-RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQ 64
+G G+ V C+ + C D F C PG + + C + PC GR C
Sbjct: 1052 LGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR--CH 1109
Query: 65 DLPDGRYQCGKCPSGFHG 82
PDGR++C +CP GF G
Sbjct: 1110 THPDGRFEC-RCPPGFGG 1126
Score = 41.9 bits (94), Expect = 0.009
Identities = 46/171 (26%), Positives = 60/171 (35%), Gaps = 29/171 (16%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPC-FGGRVPCQDLP--------------D 68
C++ FRC PG + C+++PC GGR + P
Sbjct: 238 CLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFS 297
Query: 69 GRYQCG---KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQ 125
R+ G CP GF G C + C G C++ G +C CP GY G
Sbjct: 298 FRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQC-HCPDGYAGP--T 354
Query: 126 CQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
C+ D PC C T Y C CP W G C V + C
Sbjct: 355 CEEDVDECLSDPCLHGGTC--SDTVAGYICR-CPE--TWGGRDCSVQLTGC 400
>AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein.
Length = 1282
Score = 61.3 bits (142), Expect = 1e-08
Identities = 45/142 (31%), Positives = 62/142 (43%), Gaps = 11/142 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D G+ C G + + + R C A+PC G C++LP G Y C +CP+GF
Sbjct: 634 GGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGG-SCRNLP-GAYVC-RCPAGF 690
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA--QKPCGR 138
G E +C ++ C G CE C CP + G C+ V D PCG
Sbjct: 691 VGVHCETEVDACDSSPCQHGGRCESGGGAYLC-VCPESFF--GYHCETVSDPCFSSPCGG 747
Query: 139 ERRCMPKSTSPYYECEGCPSGY 160
C+ + S + C C GY
Sbjct: 748 RGYCLASNGS--HSCT-CKVGY 766
Score = 59.7 bits (138), Expect = 4e-08
Identities = 44/130 (33%), Positives = 56/130 (43%), Gaps = 11/130 (8%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGP 110
C + PC G CQD G Y C C +G+ G E R CRA+ C G SC
Sbjct: 626 CRSQPCLHGG-SCQDRVAG-YLC-LCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAY 682
Query: 111 KCGSCPTGYVGDGRQCQ-HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD 169
C CP G+VG + + CD+ PC RC +S Y C CP + GY C
Sbjct: 683 VC-RCPAGFVGVHCETEVDACDS-SPCQHGGRC--ESGGGAYLCV-CPESF--FGYHCET 735
Query: 170 MDECDLIRPC 179
+ + PC
Sbjct: 736 VSDPCFSSPC 745
Score = 53.6 bits (123), Expect = 3e-06
Identities = 46/144 (31%), Positives = 61/144 (42%), Gaps = 17/144 (11%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYG 109
C ++PCF G C D D Y C +CP GFHG E R C + C G +C+E
Sbjct: 414 CDSDPCFNGG-SC-DAHDDSYTC-ECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGE 470
Query: 110 PKCGSCPTGYVGDGRQCQ----HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGY 165
C SCP Y GR C+ C A PC C Y+C+ CP G+ +G
Sbjct: 471 YHC-SCP--YRFTGRHCEIGKPDSC-ASGPCHNGGTCFHYIGK--YKCD-CPPGF--SGR 521
Query: 166 TCVDMDECDLIRPCDDLVSCRNEE 189
C PC + +C + +
Sbjct: 522 HCEIAPSPCFRSPCVNGGTCEDRD 545
Score = 50.4 bits (115), Expect = 2e-05
Identities = 36/119 (30%), Positives = 50/119 (42%), Gaps = 13/119 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRT----ACSANPCFGGRVPCQDLPDGRYQCGKC 76
G C + + C CP T G+ C +C++ PC G + G+Y+C C
Sbjct: 461 GGTCKEAGGEYHCS-CPYRFT--GRHCEIGKPDSCASGPCHNGGTCFHYI--GKYKCD-C 514
Query: 77 PSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
P GF G E C + C G +CE+ C C GY+ GR+CQ D P
Sbjct: 515 PPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFC-HCQAGYM--GRRCQAEVDCGPP 570
Score = 41.5 bits (93), Expect = 0.011
Identities = 31/126 (24%), Positives = 48/126 (38%), Gaps = 9/126 (7%)
Query: 1 MHAGSMGDAGSMVTPFKLCV-GERCVDTD-QGFRCERCPGSQTSDGQTCR---TACSANP 55
+ G G S+ + C+ G +C+D G C G+ C C++ P
Sbjct: 129 VRVGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQP 188
Query: 56 CFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSC 115
C G + ++C +CP+GF G E + C C G C + + G C
Sbjct: 189 CQNGGTCTHGI--NSFRC-QCPAGFGGPTCETAQSPCDTKECQHGGQC-QVENGSAVCVC 244
Query: 116 PTGYVG 121
GY G
Sbjct: 245 QAGYTG 250
Score = 39.1 bits (87), Expect = 0.061
Identities = 49/145 (33%), Positives = 57/145 (39%), Gaps = 19/145 (13%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSAN-PC-FGGRVPCQDLPDGRYQCGKCPS 78
G CVD DQG+ CE CP + G CR + C GGR C L C +CP
Sbjct: 310 GGTCVDADQGYVCE-CP--EGFMGLDCRERVPDDCECRNGGR--C--LGANTTLC-QCPL 361
Query: 79 GFHG--NGVECYRISCRANT-CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
GF G E + C NT C G C E C C T + CD+ P
Sbjct: 362 GFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLC-VCHTDH-NASHSLPSPCDSD-P 418
Query: 136 CGRERRCMPKSTSPYYECEGCPSGY 160
C C S Y CE CP G+
Sbjct: 419 CFNGGSCDAHDDS--YTCE-CPRGF 440
>AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein.
Length = 1365
Score = 61.3 bits (142), Expect = 1e-08
Identities = 64/238 (26%), Positives = 97/238 (40%), Gaps = 32/238 (13%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDG-QTC----RTACSANPCFGGRVPCQDLPDGRYQ 72
LC G C +T+ +RCE PG Q S C SA+ C GR C +L G+YQ
Sbjct: 1123 LCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGR--CVNL-IGKYQ 1179
Query: 73 CGKCPSGFHGNGVECYRISCRANTCFQG---VSCEETQYGPKCGSCPTGY--VGDGRQCQ 127
C C G+H + + + G C ++ +C SC G+ + D R C
Sbjct: 1180 CA-CNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYEC-SCQPGFALMPDQRSCT 1237
Query: 128 HV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLIRPCDDLV 183
+ C+ +C + Y C C G+ + TCVD++ECDL
Sbjct: 1238 DIDECEDNPNICDGGQC--TNIPGEYRCL-CYDGFMASEDMKTCVDVNECDLNPNICLSG 1294
Query: 184 SCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNT 241
+C N + G+ G ++ + C D++EC G NC + +C NT
Sbjct: 1295 TCENTK-------GSFICHCDMGYSG---KKGKTGCTDINECEIGAHNCGKHAVCTNT 1342
Score = 50.4 bits (115), Expect = 2e-05
Identities = 53/189 (28%), Positives = 72/189 (38%), Gaps = 27/189 (14%)
Query: 8 DAGSMVTPFKLCVGERCVDTDQGFRCERCPGSQTS-DGQTCRTACSANPCFGGRVPCQDL 66
D TP +C+ RCV+TD +RCE PG DG+ C + C+GG
Sbjct: 613 DINECETP-GICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGG------- 664
Query: 67 PDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCE------ETQYGPKCGSCPTGYV 120
Y+ G+C G V C + G C+ +Y C S P G
Sbjct: 665 ----YKRGQCIKPLFG-AVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGP-GMT 718
Query: 121 GDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWN--GYTCVDMDECDLIRP 178
G C C ++ Y+C C SGY+ + G CVD++EC L
Sbjct: 719 SAGSDINE-CALDPDICPNGIC--ENLRGTYKCI-CNSGYEVDSTGKNCVDINECVLNSL 774
Query: 179 CDDLVSCRN 187
D CRN
Sbjct: 775 LCDNGQCRN 783
Score = 49.2 bits (112), Expect = 6e-05
Identities = 76/286 (26%), Positives = 104/286 (36%), Gaps = 53/286 (18%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQ-TSDGQTCR--TACSA-NPCFGGRVPCQDLPDGRYQC 73
+C+ C++ D F+C PG Q SDG+ C+ C C GR C + DG Y+C
Sbjct: 581 MCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGR--CVNT-DGSYRC 637
Query: 74 GKCPSGFHG-NGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVC-D 131
P G +G C R+ TC+ G K G C G + + C
Sbjct: 638 ECFPGLAVGLDGRVCVDTHMRS-TCYGGY---------KRGQCIKPLFGAVTKSECCCAS 687
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV--DMDECDLIRPCDDLVSCRNEE 189
+ G + P S Y+ C SG G T D++EC L C N
Sbjct: 688 TEYAFGEPCQPCPAQNSAEYQAL-CSSG---PGMTSAGSDINECALDPDICPNGICENLR 743
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPV 249
S G ++CVD++EC C G+ C NTP
Sbjct: 744 GTYKCICNSGYEVDSTG----------KNCVDINECVLNSLLCDNGQ-CRNTP------- 785
Query: 250 SSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC 295
GS++C G Y + C D D C+ S C N VC
Sbjct: 786 ----GSFVCTCPKGFIYKPDLKTCEDID----ECESSPC--INGVC 821
Score = 48.8 bits (111), Expect = 8e-05
Identities = 51/170 (30%), Positives = 70/170 (41%), Gaps = 23/170 (13%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGK 75
LC RC+ T RCE G Q C C NPC GG C + G Y C +
Sbjct: 459 LCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGGE--CIN-NQGSYTC-Q 514
Query: 76 CPSGFHG--NGVECYRI-SCRAN--TCFQGVSCEETQYGPKCGSCPTGY--VGDGRQCQH 128
C +G+ EC I C N C G C T C C G+ DG+ C+
Sbjct: 515 CRAGYQSTLTRTECRDIDECLQNGRICNNG-RCINTDGSFHC-VCNAGFHVTRDGKNCED 572
Query: 129 V--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECD 174
+ C + C C+ + S ++C C G+Q +G C D++EC+
Sbjct: 573 MDECSIRNMC-LNGMCINEDGS--FKCI-CKPGFQLASDGRYCKDINECE 618
Score = 43.6 bits (98), Expect = 0.003
Identities = 51/179 (28%), Positives = 69/179 (38%), Gaps = 36/179 (20%)
Query: 141 RCMPKSTSPYYECEGCPSGYQWN-GYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXX 199
RC+P S CE C G+Q + C+D+DEC+ PC C N +
Sbjct: 464 RCIPTPGS--CRCE-CNKGFQLDLRGECIDVDECEK-NPCAG-GECINNQGSYTCQCRA- 517
Query: 200 XXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICV 259
G++ T R C D+DEC C GR C+NT GS+ CV
Sbjct: 518 ------GYQST---LTRTECRDIDECLQNGRICNNGR-CINT-----------DGSFHCV 556
Query: 260 PCGGHYYVNTTRPCFDPD--SLVKRCDPSYCRRFNAVCGFGQKCVCNTGW--TGNGTVC 314
G + + C D D S+ C C N F KC+C G+ +G C
Sbjct: 557 CNAGFHVTRDGKNCEDMDECSIRNMCLNGMC--INEDGSF--KCICKPGFQLASDGRYC 611
Score = 43.2 bits (97), Expect = 0.004
Identities = 40/119 (33%), Positives = 51/119 (42%), Gaps = 14/119 (11%)
Query: 17 KLCVGERCVDTDQGFRCERCPGSQ-TSDGQTCR--TACS-ANPCFGGRVPCQDLPDGRYQ 72
++C RC++TD F C G T DG+ C CS N C G C + DG ++
Sbjct: 539 RICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGM--CIN-EDGSFK 595
Query: 73 CGKCPSGFH--GNGVECYRIS-CRA-NTCFQGVSCEETQYGPKCGSCPTGYVG-DGRQC 126
C C GF +G C I+ C C G C T +C P VG DGR C
Sbjct: 596 C-ICKPGFQLASDGRYCKDINECETPGICMNG-RCVNTDGSYRCECFPGLAVGLDGRVC 652
Score = 42.3 bits (95), Expect = 0.007
Identities = 37/119 (31%), Positives = 53/119 (44%), Gaps = 15/119 (12%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTS-DGQTCRTA--CSANP--CFGGRVPCQDLPDGRYQ 72
+C G +C + +RC G S D +TC C NP C G C++ G +
Sbjct: 1248 ICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGT--CENTK-GSFI 1304
Query: 73 CGKCPSGFHGNGVE--CYRIS-CR--ANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQC 126
C C G+ G + C I+ C A+ C + C T KC SC G++GDG +C
Sbjct: 1305 C-HCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKC-SCSPGWIGDGIKC 1361
Score = 40.3 bits (90), Expect = 0.026
Identities = 54/194 (27%), Positives = 75/194 (38%), Gaps = 30/194 (15%)
Query: 56 CFGGRVPCQDLPDGRYQCGKCPSGFHGN-GVECYRIS-CRANTCFQGVSCEETQYGPKCG 113
C GR C P G +C +C GF + EC + C N C G C Q C
Sbjct: 460 CQNGR--CIPTP-GSCRC-ECNKGFQLDLRGECIDVDECEKNPCAGG-ECINNQGSYTC- 513
Query: 114 SCPTGYVGD--GRQCQHV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTC 167
C GY +C+ + C RC+ +T + C C +G+ +G C
Sbjct: 514 QCRAGYQSTLTRTECRDIDECLQNGRICNNGRCI--NTDGSFHCV-CNAGFHVTRDGKNC 570
Query: 168 VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECAD 227
DMDEC + C + + C NE+ S G +C D++EC +
Sbjct: 571 EDMDECSIRNMCLNGM-CINEDGSFKCICKPGFQLASDG----------RYCKDINEC-E 618
Query: 228 GRANCPRGRLCVNT 241
C GR CVNT
Sbjct: 619 TPGICMNGR-CVNT 631
Score = 36.3 bits (80), Expect = 0.43
Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 15/93 (16%)
Query: 18 LCVGERCVDTDQGFRCERCP-GSQTSD-GQTCR--TACSANP--CFGGRVPCQDLPDGRY 71
LC G C++T F C +CP G + ++ Q C CS P C GG C + Y
Sbjct: 256 LCQGGNCINTVGSFEC-KCPAGHKLNEVSQKCEDIDECSTIPGICEGGE--CTNTVSS-Y 311
Query: 72 QCGKCPSGFH--GNGVECYRISCRANTCFQGVS 102
C KCP GF+ +G C I R C+ ++
Sbjct: 312 FC-KCPPGFYTSPDGTRC--IDVRPGYCYTALT 341
Score = 35.9 bits (79), Expect = 0.57
Identities = 70/302 (23%), Positives = 110/302 (36%), Gaps = 47/302 (15%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSD--GQTCRTACSANPCFGGRVPCQD--LP-DGRYQ 72
+C CV+T F+C+ CP T D G+ C CF R ++ LP GR++
Sbjct: 920 VCKNGLCVNTRGSFKCQ-CPSGMTLDATGRICLDI-RLETCFL-RYEDEECTLPIAGRHR 976
Query: 73 CGKC--PSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVC 130
C G EC R ++ + + K + + D +C+ +
Sbjct: 977 MDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIP 1036
Query: 131 DAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGY--TCVDMDECDLIRPCDDLVSCRNE 188
C +C ++T ++C C SG+ + C D+DEC + C N
Sbjct: 1037 SL---C-THGKC--RNTIGSFKCR-CDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 1089
Query: 189 EXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNP 248
+G+ ++C+D+DEC C RG +C NT
Sbjct: 1090 PGDFECKC-------DEGYES--GFMMMKNCMDIDECQRDPLLC-RGGVCHNT------- 1132
Query: 249 VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPS--YCRRFNAVCGFGQ-KCVCNT 305
+GSY C GH C D + C+ S C V G+ +C CN
Sbjct: 1133 ----EGSYRCECPPGHQLSPNISACID----INECELSAHLCPNGRCVNLIGKYQCACNP 1184
Query: 306 GW 307
G+
Sbjct: 1185 GY 1186
>AY227444-1|AAO39681.1| 1416|Homo sapiens hyaluronan receptor for
endocytosis precursor protein.
Length = 1416
Score = 60.9 bits (141), Expect = 2e-08
Identities = 45/160 (28%), Positives = 61/160 (38%), Gaps = 17/160 (10%)
Query: 20 VGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSG 79
+G+ D D G+R C + T D C C + C DG C KC +G
Sbjct: 276 LGDGSCDCDVGWRGVHCDNATTEDN--CNGTCHTS------ANCLTNSDGTASC-KCAAG 326
Query: 80 FHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--C-DAQ 133
F GNG C I+ C + C C+ T G + +C GY GDG C + C +
Sbjct: 327 FQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENH 386
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC 173
C + C T P C Y +G C + C
Sbjct: 387 GGCDKNAEC--TQTGPNQAACNCLPAYTGDGKVCTLIYVC 424
Score = 51.2 bits (117), Expect = 1e-05
Identities = 75/308 (24%), Positives = 111/308 (36%), Gaps = 54/308 (17%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHG 82
+CV T C C G Q C + N CFG + C D +G C +C GF G
Sbjct: 191 KCVRTVITREC--CAGFFGPQCQPC-PGNAQNVCFGNGI-CLDGVNGTGVC-ECGEGFSG 245
Query: 83 NGVE-C----YRISC-RANTCFQGVSCEETQYGPKCGSCPTGYVG---DGRQCQHVCDAQ 133
E C Y I C +A +C G C + G C G+ G D + C+
Sbjct: 246 TACETCTEGKYGIHCDQACSCVHG-RCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGT 304
Query: 134 KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIR-PCDDLVSCRNEEXXX 192
C C+ S C+ C +G+Q NG C ++ C++ C C+
Sbjct: 305 --CHTSANCLTNSDGTA-SCK-CAAGFQGNGTICTAINACEISNGGCSAKADCKR----- 355
Query: 193 XXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSL 252
G+ G G C++++ C + C + C T P+
Sbjct: 356 -TTPGRRVCTCKAGYTGDGIV-----CLEINPCLENHGGCDKNAECTQTG--PN------ 401
Query: 253 QGSYICVPCGGHYYVNTTRPCFDPDSLVKRC--DPSYCRRFNAVCGF-GQ---KCVCNTG 306
Q + C+P Y + C +L+ C C F A+C GQ C C
Sbjct: 402 QAACNCLPA----YTGDGKVC----TLIYVCLTKNGGCSEF-AICNHTGQVERTCTCKPN 452
Query: 307 WTGNGTVC 314
+ G+G C
Sbjct: 453 YIGDGFTC 460
Score = 47.2 bits (107), Expect = 2e-04
Identities = 49/172 (28%), Positives = 68/172 (39%), Gaps = 24/172 (13%)
Query: 23 RCVDTDQGFRCERC-PGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
+C G CE C PG D C CS + G+ C D G QC C +G+
Sbjct: 852 KCNTGFNGTACEMCWPGRFGPDCLPC--GCSDH----GQ--CDDGITGSGQC-LCETGWT 902
Query: 82 GNGVECYRISCRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKP-C 136
G + + T C +C+E C C Y GDG C V C C
Sbjct: 903 GPSCDTQAVLPAVCTPPCSAHATCKENN---TC-ECNLDYEGDGITCTVVDFCKQDNGGC 958
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC--DLIRPCDDLVSCR 186
+ RC K T C C GY+ +G++C ++D C L C + +C+
Sbjct: 959 AKVARCSQKGTK--VSCS-CQKGYKGDGHSCTEIDPCADGLNGGCHEHATCK 1007
Score = 42.3 bits (95), Expect = 0.007
Identities = 46/177 (25%), Positives = 64/177 (36%), Gaps = 45/177 (25%)
Query: 92 CRANTCFQGVSCE---ETQYGPKC--------GSCPTGYVGDGR-QCQ-----HVCDAQ- 133
C+ NT F G +CE ++GP C G C G G G+ C+ CD Q
Sbjct: 851 CKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQA 910
Query: 134 -------KPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIR-PCDDLVSC 185
PC C +T CE C Y+ +G TC +D C C + C
Sbjct: 911 VLPAVCTPPCSAHATCKENNT-----CE-CNLDYEGDGITCTVVDFCKQDNGGCAKVARC 964
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADG-RANCPRGRLCVNT 241
+ +G++G G+ C ++D CADG C C T
Sbjct: 965 SQK-------GTKVSCSCQKGYKGDGHS-----CTEIDPCADGLNGGCHEHATCKMT 1009
Score = 37.1 bits (82), Expect = 0.25
Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 8/101 (7%)
Query: 33 CERCPGSQTSDGQTCRTACSANPCFGG--RVPCQDLPDGRYQCGKCPSGFHGNGVECYRI 90
CE C DG TC GG +V + C C G+ G+G C I
Sbjct: 932 CE-CNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCS-CQKGYKGDGHSCTEI 989
Query: 91 SCRANT----CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ 127
A+ C + +C+ T G C + YVGDG C+
Sbjct: 990 DPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCE 1030
>BC127263-1|AAI27264.1| 363|Homo sapiens SCUBE1 protein protein.
Length = 363
Score = 60.5 bits (140), Expect = 2e-08
Identities = 50/168 (29%), Positives = 77/168 (45%), Gaps = 17/168 (10%)
Query: 24 CVDTDQG-FRCERCPGSQTSDGQT-CRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF- 80
C +T +G C+ PG + Q C C+ G + C+D G CG C +
Sbjct: 177 CRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNG-GCQHSCEDTDTGP-MCG-CHQKYA 233
Query: 81 -HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQCQHVCDAQ-KPC 136
H +G C +C N +C++T G +C SCP G+ DG+ C+ + +
Sbjct: 234 LHSDGRTCIE-TCAVNNGGCDRTCKDTATGVRC-SCPVGFTLQPDGKTCKDINECLVNNG 291
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDL 182
G + C ++T +EC GC GY+ + TC D+DEC R CD +
Sbjct: 292 GCDHFC--RNTVGSFEC-GCRKGYKLLTDERTCQDIDECSFERTCDHI 336
Score = 41.5 bits (93), Expect = 0.011
Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 10/101 (9%)
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPC- 136
SG G+ V+ S + C C+ T KC C GY G+G+QC+ + + +
Sbjct: 26 SGLPGS-VDVDECSEGTDDCHIDAICQNTPKSYKC-LCKPGYKGEGKQCEDIDECENDYY 83
Query: 137 --GRERRCMPKSTSPYYECEGCPSGYQ--WNGYTCVDMDEC 173
G C+ + Y C C G+ +G+ C+D+DEC
Sbjct: 84 NGGCVHECI--NIPGNYRCT-CFDGFMLAHDGHNCLDVDEC 121
Score = 32.7 bits (71), Expect = 5.3
Identities = 12/24 (50%), Positives = 17/24 (70%)
Query: 220 VDVDECADGRANCPRGRLCVNTPQ 243
VDVDEC++G +C +C NTP+
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPK 55
>AK131562-1|BAD18695.1| 867|Homo sapiens protein ( Homo sapiens
cDNA FLJ16811 fis, clone THYMU3024602, highly similar
to Cell surface glycoprotein EMR1 precursor. ).
Length = 867
Score = 59.7 bits (138), Expect = 4e-08
Identities = 68/266 (25%), Positives = 93/266 (34%), Gaps = 36/266 (13%)
Query: 91 SCRANT-CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKSTSP 149
+CR +T C +C T C +C G++ Q H D C C+ S P
Sbjct: 34 NCRDSTLCPAYATCTNTVDSYYC-ACKQGFLSSNGQ-NHFKDPGVRCKDINECLTSSVCP 91
Query: 150 Y----------YECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXX 199
Y C C G+ TC D+DEC R C + +C N
Sbjct: 92 EHSDCVNSMGSYSCS-CQVGFISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPG 150
Query: 200 XXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICV 259
S G + C D+DEC + CP C NTP GSY C
Sbjct: 151 FESSSGHLSFQG---LKASCEDIDECTE---MCPINSTCTNTP-----------GSYFCT 193
Query: 260 PCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDRD 319
C + + + F D V+ D CR+ + CG C G G + G +
Sbjct: 194 -CHPGFAPSNGQLNF-TDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPN 251
Query: 320 LDG-HPDEQLPCNEP--RCKKDNCPD 342
+G D C +CK+D PD
Sbjct: 252 PEGSQKDGNFSCQRVLFKCKEDVIPD 277
>AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein.
Length = 1534
Score = 59.3 bits (137), Expect = 5e-08
Identities = 49/165 (29%), Positives = 69/165 (41%), Gaps = 18/165 (10%)
Query: 31 FRCERCP-GSQTSDGQTCRTACSANPC-FGGRVPCQDLPDGRYQCGKCPSGFHGNGVECY 88
+RC CP G + D + +CS+ PC GG Q+ D + C CP+GF G
Sbjct: 948 YRCA-CPSGYKGRDCEVSLNSCSSGPCENGGTCHAQEGEDAPFTC-SCPTGFEGPTCGVN 1005
Query: 89 RISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA----QKPCGRERRCMP 144
C + C G C + C CP Y +G+ C+ + D PC E +C+
Sbjct: 1006 TDDCVDHACANGGVCVDGVGNYTC-QCPLQY--EGKACEQLVDLCSPDLNPCQHEAQCVG 1062
Query: 145 KSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRPCDDLVSCRNE 188
P CE C GY G C + D+C R C + C +E
Sbjct: 1063 TPDGP--RCE-CMPGYA--GDNCSENQDDCRDHR-CQNGAQCMDE 1101
Score = 54.8 bits (126), Expect = 1e-06
Identities = 48/157 (30%), Positives = 65/157 (41%), Gaps = 17/157 (10%)
Query: 36 CPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRAN 95
C G T Q C ++PC + C + P Y+C CPSG+ G E SC +
Sbjct: 914 CQGPPTLAVQAKCDLCLSSPC-QNQGTCHNDPLEVYRCA-CPSGYKGRDCEVSLNSCSSG 971
Query: 96 TCFQGVSC--EETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKSTSPYY 151
C G +C +E + P SCPTG+ +G C D C C+ + Y
Sbjct: 972 PCENGGTCHAQEGEDAPFTCSCPTGF--EGPTCGVNTDDCVDHACANGGVCVDGVGN--Y 1027
Query: 152 ECEGCPSGYQWNGYTC---VDMDECDLIRPCDDLVSC 185
C+ CP Q+ G C VD+ DL PC C
Sbjct: 1028 TCQ-CP--LQYEGKACEQLVDLCSPDL-NPCQHEAQC 1060
Score = 37.1 bits (82), Expect = 0.25
Identities = 29/105 (27%), Positives = 39/105 (37%), Gaps = 10/105 (9%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHG 82
+CV T G RCE PG + + C + C G C D + Y C C G+ G
Sbjct: 1059 QCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNG-AQCMDEVNS-YSC-LCAEGYSG 1115
Query: 83 NGVE------CYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG 121
E + C C G +C + P C C G+ G
Sbjct: 1116 QLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVC-QCLPGFGG 1159
>BC000218-1|AAH00218.1| 618|Homo sapiens delta-like 3 (Drosophila)
protein.
Length = 618
Score = 58.8 bits (136), Expect = 7e-08
Identities = 43/127 (33%), Positives = 55/127 (43%), Gaps = 10/127 (7%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCP 77
LCVG D D + C PG Q S+ + CS PC G + C DL +C +C
Sbjct: 326 LCVGG--ADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGL-CLDLGHA-LRC-RCR 380
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKP 135
+GF G E C C G +C E +C SC G+ GR C+ D A +P
Sbjct: 381 AGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRC-SCALGF--GGRDCRERADPCAARP 437
Query: 136 CGRERRC 142
C RC
Sbjct: 438 CAHGGRC 444
Score = 46.0 bits (104), Expect = 5e-04
Identities = 37/129 (28%), Positives = 54/129 (41%), Gaps = 17/129 (13%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSC---EETQ 107
C NPC G C + P ++C CP GF+G E ++C CF G C +
Sbjct: 278 CDGNPCANGG-SCSETPRS-FEC-TCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPD 334
Query: 108 YGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGY 165
C CP G+ G C+ D + +PC C+ + C C +G+ G
Sbjct: 335 SAYIC-HCPPGF--QGSNCEKRVDRCSLQPCRNGGLCLDLGHA--LRCR-CRAGFA--GP 386
Query: 166 TCV-DMDEC 173
C D+D+C
Sbjct: 387 RCEHDLDDC 395
>AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosophila)
protein.
Length = 1534
Score = 58.8 bits (136), Expect = 7e-08
Identities = 49/165 (29%), Positives = 69/165 (41%), Gaps = 18/165 (10%)
Query: 31 FRCERCP-GSQTSDGQTCRTACSANPC-FGGRVPCQDLPDGRYQCGKCPSGFHGNGVECY 88
+RC CP G + D + +CS+ PC GG Q+ D + C CP+GF G
Sbjct: 948 YRCA-CPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTC-SCPTGFEGPTCGVN 1005
Query: 89 RISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA----QKPCGRERRCMP 144
C + C G C + C CP Y +G+ C+ + D PC E +C+
Sbjct: 1006 TDDCVDHACANGGVCVDGVGNYTC-QCPLQY--EGKACEQLVDLCSPDLNPCQHEAQCVG 1062
Query: 145 KSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRPCDDLVSCRNE 188
P CE C GY G C + D+C R C + C +E
Sbjct: 1063 TPDGP--RCE-CMPGYA--GDNCSENQDDCRDHR-CQNGAQCMDE 1101
Score = 54.8 bits (126), Expect = 1e-06
Identities = 48/157 (30%), Positives = 65/157 (41%), Gaps = 17/157 (10%)
Query: 36 CPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRAN 95
C G T Q C ++PC + C + P Y+C CPSG+ G E SC +
Sbjct: 914 CQGPPTLAVQAKCDLCLSSPC-QNQGTCHNDPLEVYRCA-CPSGYKGRDCEVSLDSCSSG 971
Query: 96 TCFQGVSC--EETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKSTSPYY 151
C G +C +E + P SCPTG+ +G C D C C+ + Y
Sbjct: 972 PCENGGTCHAQEGEDAPFTCSCPTGF--EGPTCGVNTDDCVDHACANGGVCVDGVGN--Y 1027
Query: 152 ECEGCPSGYQWNGYTC---VDMDECDLIRPCDDLVSC 185
C+ CP Q+ G C VD+ DL PC C
Sbjct: 1028 TCQ-CP--LQYEGKACEQLVDLCSPDL-NPCQHEAQC 1060
Score = 37.1 bits (82), Expect = 0.25
Identities = 29/105 (27%), Positives = 39/105 (37%), Gaps = 10/105 (9%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHG 82
+CV T G RCE PG + + C + C G C D + Y C C G+ G
Sbjct: 1059 QCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNG-AQCMDEVNS-YSC-LCAEGYSG 1115
Query: 83 NGVE------CYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG 121
E + C C G +C + P C C G+ G
Sbjct: 1116 QLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVC-QCLPGFGG 1159
>AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosophila)
protein.
Length = 1461
Score = 58.8 bits (136), Expect = 7e-08
Identities = 49/165 (29%), Positives = 69/165 (41%), Gaps = 18/165 (10%)
Query: 31 FRCERCP-GSQTSDGQTCRTACSANPC-FGGRVPCQDLPDGRYQCGKCPSGFHGNGVECY 88
+RC CP G + D + +CS+ PC GG Q+ D + C CP+GF G
Sbjct: 948 YRCA-CPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTC-SCPTGFEGPTCGVN 1005
Query: 89 RISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA----QKPCGRERRCMP 144
C + C G C + C CP Y +G+ C+ + D PC E +C+
Sbjct: 1006 TDDCVDHACANGGVCVDGVGNYTC-QCPLQY--EGKACEQLVDLCSPDLNPCQHEAQCVG 1062
Query: 145 KSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRPCDDLVSCRNE 188
P CE C GY G C + D+C R C + C +E
Sbjct: 1063 TPDGP--RCE-CMPGYA--GDNCSENQDDCRDHR-CQNGAQCMDE 1101
Score = 54.8 bits (126), Expect = 1e-06
Identities = 48/157 (30%), Positives = 65/157 (41%), Gaps = 17/157 (10%)
Query: 36 CPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRAN 95
C G T Q C ++PC + C + P Y+C CPSG+ G E SC +
Sbjct: 914 CQGPPTLAVQAKCDLCLSSPC-QNQGTCHNDPLEVYRCA-CPSGYKGRDCEVSLDSCSSG 971
Query: 96 TCFQGVSC--EETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKSTSPYY 151
C G +C +E + P SCPTG+ +G C D C C+ + Y
Sbjct: 972 PCENGGTCHAQEGEDAPFTCSCPTGF--EGPTCGVNTDDCVDHACANGGVCVDGVGN--Y 1027
Query: 152 ECEGCPSGYQWNGYTC---VDMDECDLIRPCDDLVSC 185
C+ CP Q+ G C VD+ DL PC C
Sbjct: 1028 TCQ-CP--LQYEGKACEQLVDLCSPDL-NPCQHEAQC 1060
Score = 37.1 bits (82), Expect = 0.25
Identities = 29/105 (27%), Positives = 39/105 (37%), Gaps = 10/105 (9%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHG 82
+CV T G RCE PG + + C + C G C D + Y C C G+ G
Sbjct: 1059 QCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNG-AQCMDEVNS-YSC-LCAEGYSG 1115
Query: 83 NGVE------CYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG 121
E + C C G +C + P C C G+ G
Sbjct: 1116 QLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVC-QCLPGFGG 1159
>AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosophila)
protein.
Length = 1461
Score = 58.8 bits (136), Expect = 7e-08
Identities = 49/165 (29%), Positives = 69/165 (41%), Gaps = 18/165 (10%)
Query: 31 FRCERCP-GSQTSDGQTCRTACSANPC-FGGRVPCQDLPDGRYQCGKCPSGFHGNGVECY 88
+RC CP G + D + +CS+ PC GG Q+ D + C CP+GF G
Sbjct: 948 YRCA-CPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTC-SCPTGFEGPTCGVN 1005
Query: 89 RISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA----QKPCGRERRCMP 144
C + C G C + C CP Y +G+ C+ + D PC E +C+
Sbjct: 1006 TDDCVDHACANGGVCVDGVGNYTC-QCPLQY--EGKACEQLVDLCSPDLNPCQHEAQCVG 1062
Query: 145 KSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRPCDDLVSCRNE 188
P CE C GY G C + D+C R C + C +E
Sbjct: 1063 TPDGP--RCE-CMPGYA--GDNCSENQDDCRDHR-CQNGAQCMDE 1101
Score = 54.8 bits (126), Expect = 1e-06
Identities = 48/157 (30%), Positives = 65/157 (41%), Gaps = 17/157 (10%)
Query: 36 CPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRAN 95
C G T Q C ++PC + C + P Y+C CPSG+ G E SC +
Sbjct: 914 CQGPPTLAVQAKCDLCLSSPC-QNQGTCHNDPLEVYRCA-CPSGYKGRDCEVSLDSCSSG 971
Query: 96 TCFQGVSC--EETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKSTSPYY 151
C G +C +E + P SCPTG+ +G C D C C+ + Y
Sbjct: 972 PCENGGTCHAQEGEDAPFTCSCPTGF--EGPTCGVNTDDCVDHACANGGVCVDGVGN--Y 1027
Query: 152 ECEGCPSGYQWNGYTC---VDMDECDLIRPCDDLVSC 185
C+ CP Q+ G C VD+ DL PC C
Sbjct: 1028 TCQ-CP--LQYEGKACEQLVDLCSPDL-NPCQHEAQC 1060
Score = 37.1 bits (82), Expect = 0.25
Identities = 29/105 (27%), Positives = 39/105 (37%), Gaps = 10/105 (9%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHG 82
+CV T G RCE PG + + C + C G C D + Y C C G+ G
Sbjct: 1059 QCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNG-AQCMDEVNS-YSC-LCAEGYSG 1115
Query: 83 NGVE------CYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG 121
E + C C G +C + P C C G+ G
Sbjct: 1116 QLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVC-QCLPGFGG 1159
>AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosophila)
protein.
Length = 1534
Score = 58.8 bits (136), Expect = 7e-08
Identities = 49/165 (29%), Positives = 69/165 (41%), Gaps = 18/165 (10%)
Query: 31 FRCERCP-GSQTSDGQTCRTACSANPC-FGGRVPCQDLPDGRYQCGKCPSGFHGNGVECY 88
+RC CP G + D + +CS+ PC GG Q+ D + C CP+GF G
Sbjct: 948 YRCA-CPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTC-SCPTGFEGPTCGVN 1005
Query: 89 RISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA----QKPCGRERRCMP 144
C + C G C + C CP Y +G+ C+ + D PC E +C+
Sbjct: 1006 TDDCVDHACANGGVCVDGVGNYTC-QCPLQY--EGKACEQLVDLCSPDLNPCQHEAQCVG 1062
Query: 145 KSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRPCDDLVSCRNE 188
P CE C GY G C + D+C R C + C +E
Sbjct: 1063 TPDGP--RCE-CMPGYA--GDNCSENQDDCRDHR-CQNGAQCMDE 1101
Score = 54.8 bits (126), Expect = 1e-06
Identities = 48/157 (30%), Positives = 65/157 (41%), Gaps = 17/157 (10%)
Query: 36 CPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRAN 95
C G T Q C ++PC + C + P Y+C CPSG+ G E SC +
Sbjct: 914 CQGPPTLAVQAKCDLCLSSPC-QNQGTCHNDPLEVYRCA-CPSGYKGRDCEVSLDSCSSG 971
Query: 96 TCFQGVSC--EETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKSTSPYY 151
C G +C +E + P SCPTG+ +G C D C C+ + Y
Sbjct: 972 PCENGGTCHAQEGEDAPFTCSCPTGF--EGPTCGVNTDDCVDHACANGGVCVDGVGN--Y 1027
Query: 152 ECEGCPSGYQWNGYTC---VDMDECDLIRPCDDLVSC 185
C+ CP Q+ G C VD+ DL PC C
Sbjct: 1028 TCQ-CP--LQYEGKACEQLVDLCSPDL-NPCQHEAQC 1060
Score = 37.1 bits (82), Expect = 0.25
Identities = 29/105 (27%), Positives = 39/105 (37%), Gaps = 10/105 (9%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHG 82
+CV T G RCE PG + + C + C G C D + Y C C G+ G
Sbjct: 1059 QCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNG-AQCMDEVNS-YSC-LCAEGYSG 1115
Query: 83 NGVE------CYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG 121
E + C C G +C + P C C G+ G
Sbjct: 1116 QLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVC-QCLPGFGG 1159
>AK131282-1|BAD18457.1| 872|Homo sapiens protein ( Homo sapiens
cDNA FLJ16233 fis, clone FEBRA2028256, moderately
similar to FIBRILLIN 2 PRECURSOR. ).
Length = 872
Score = 58.8 bits (136), Expect = 7e-08
Identities = 56/172 (32%), Positives = 75/172 (43%), Gaps = 25/172 (14%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSD--GQTC--RTACS-ANPCFGGRVPCQDLPDGRYQ 72
+C CV+TD FRCE CP + D G C CS +PC G+ C ++ G ++
Sbjct: 200 VCTNGVCVNTDGSFRCE-CPFGYSLDFTGINCVDTDECSVGHPC--GQGTCTNVIGG-FE 255
Query: 73 CGKCPSGFH-GNGVECYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQCQH 128
C C GF G + C I C N C T+ C +CP GY DG C+
Sbjct: 256 CA-CADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLC-TCPAGYTLREDGAMCRD 313
Query: 129 V---CDAQKPC-GRERRCMPKSTSPYYECEGCPSGYQ---WNGYTCVDMDEC 173
V D Q+ C R C K+ + C CP G + +G C D +EC
Sbjct: 314 VDECADGQQDCHARGMEC--KNLIGTFACV-CPPGMRPLPGSGEGCTDDNEC 362
Score = 55.6 bits (128), Expect = 7e-07
Identities = 83/305 (27%), Positives = 111/305 (36%), Gaps = 65/305 (21%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGG--RVPCQDLPDG-----R 70
LCV RCV+T FRC+ G Q S T PCF + C+ L R
Sbjct: 368 LCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTR 427
Query: 71 YQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCP--TGYVGDGRQCQH 128
+C C G G G C + ++ + CP +GY +GR
Sbjct: 428 AEC--CCGGGRGWGPRCELCPLPGTSAYRKL-------------CPHGSGYTAEGRDVDE 472
Query: 129 VCDAQKPCGRERRCMPKSTSPYYECEGCPSGY--QWNGYTCVDMDECDLI-RPCDDLVSC 185
C C+ S + C C +GY TC+DMDEC + +PC L C
Sbjct: 473 -CRMLAHLCAHGECINSLGS--FRCH-CQAGYTPDATATTCLDMDECSQVPKPCTFL--C 526
Query: 186 RNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYP 245
+N + RG E C D+DEC + NC LCVNT
Sbjct: 527 KNTKGSFLCSCP----------RGYLLEEDGRTCKDLDECTSRQHNCQ--FLCVNT---- 570
Query: 246 SNPVSSLQGSYIC-VPCGGHYYVNTTRPCFDPDSLVKRCD-PSYCRRFNAVCGFGQKCVC 303
G++ C P G + + CFD V CD P C+ G +C C
Sbjct: 571 -------VGAFTCRCPPG---FTQHHQACFD----VNECDGPHRCQHGCQNQLGGYRCSC 616
Query: 304 NTGWT 308
G+T
Sbjct: 617 PQGFT 621
Score = 50.4 bits (115), Expect = 2e-05
Identities = 64/225 (28%), Positives = 82/225 (36%), Gaps = 38/225 (16%)
Query: 97 CFQGVSCEETQYGPKCGSCPTGYVGD--GRQCQHV--CDAQKPCGRERRCMPKSTSPYYE 152
C GV C T +C CP GY D G C C PCG + C + +E
Sbjct: 201 CTNGV-CVNTDGSFRC-ECPFGYSLDFTGINCVDTDECSVGHPCG-QGTCT--NVIGGFE 255
Query: 153 CEGCPSGYQWN-GYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTG 211
C C G++ TC D+DEC L P C N E G
Sbjct: 256 C-ACADGFEPGLMMTCEDIDECSL-NPLLCAFRCHNTEGSYLCTCPAGYTLREDG----- 308
Query: 212 NERRREHCVDVDECADGRANC-PRGRLCVNTPQYPSNPVSSLQGSYICV-PCGGHYYVNT 269
C DVDECADG+ +C RG C N L G++ CV P G +
Sbjct: 309 -----AMCRDVDECADGQQDCHARGMECKN-----------LIGTFACVCPPGMRPLPGS 352
Query: 270 TRPCFDPDSLVKRCDPSYCRRFNAVCGFGQ-KCVCNTGWTGNGTV 313
C D + P C V G +C C+ G+ + T+
Sbjct: 353 GEGCTDDNEC--HAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTL 395
Score = 46.4 bits (105), Expect = 4e-04
Identities = 81/325 (24%), Positives = 108/325 (33%), Gaps = 60/325 (18%)
Query: 5 SMGDAGSMVTPFKLCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQ 64
S+ + VT + C G G RCE CP TS R C G +
Sbjct: 417 SLSSSSEAVTRAECCCGG---GRGWGPRCELCPLPGTS---AYRKLCPHGS--GYTAEGR 468
Query: 65 DLPDGRYQCGKCPSGFHGNGVECYRISCRAN--------TCFQGVSCEETQY-------- 108
D+ + R C G N + +R C+A TC C +
Sbjct: 469 DVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKN 528
Query: 109 --GPKCGSCPTGYV--GDGRQCQHVCDAQKPCGRERRC--MPKSTSPYYECEGCPSGYQW 162
G SCP GY+ DGR C+ D + R+ C + +T + C CP G+
Sbjct: 529 TKGSFLCSCPRGYLLEEDGRTCK---DLDECTSRQHNCQFLCVNTVGAFTCR-CPPGFTQ 584
Query: 163 NGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDV 222
+ C D++ECD C C+N+ SQ W CVD
Sbjct: 585 HHQACFDVNECDGPHRCQH--GCQNQLGGYRCSCPQGFTQHSQ-W---------AQCVDE 632
Query: 223 DECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKR 282
+ECA C C NT G + CV G + C D D R
Sbjct: 633 NECALSPPTCGSAS-CRNT-----------LGGFRCVCPSGFDFDQALGGCQDVDECAGR 680
Query: 283 CDPSYCRRFNAVCGFGQKCVCNTGW 307
P N GF C C G+
Sbjct: 681 RGPCSYSCANTPGGF--LCGCPQGY 703
Score = 37.1 bits (82), Expect = 0.25
Identities = 85/333 (25%), Positives = 117/333 (35%), Gaps = 55/333 (16%)
Query: 21 GERCVDTDQGFRCERCPGSQ----TSDGQTCRTACSANP--CFGGRVPCQDLPDGRYQCG 74
G C + F C PG + + +G T C A P C GR C + G ++C
Sbjct: 328 GMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGR--CVNTA-GSFRCD 384
Query: 75 KCPSGFHGNGV--ECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA 132
C GF + EC+ I R CF V +T C S + R + C
Sbjct: 385 -CDEGFQPSPTLTECHDI--RQGPCFAEVL--QTM----CRSLSSSSEAVTR-AECCCGG 434
Query: 133 QKPCG-RERRCMPKSTSPYYECEGCPSGYQWNGYTCV--DMDECDLIRPCDDLVSCRNEE 189
+ G R C TS Y + CP G +GYT D+DEC ++ C N
Sbjct: 435 GRGWGPRCELCPLPGTSAYRKL--CPHG---SGYTAEGRDVDECRMLAHLCAHGECINS- 488
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPV 249
G + C+D+DEC+ C LC NT
Sbjct: 489 ---------LGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTF--LCKNT-------- 529
Query: 250 SSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTG 309
+GS++C G+ R C D D R N V F C C G+T
Sbjct: 530 ---KGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGAF--TCRCPPGFTQ 584
Query: 310 NGTVCGLDRDLDGHPDEQLPC-NEPRCKKDNCP 341
+ C + DG Q C N+ + +CP
Sbjct: 585 HHQACFDVNECDGPHRCQHGCQNQLGGYRCSCP 617
>AF241373-1|AAF62542.1| 618|Homo sapiens DLL3 protein precursor
protein.
Length = 618
Score = 58.8 bits (136), Expect = 7e-08
Identities = 43/127 (33%), Positives = 55/127 (43%), Gaps = 10/127 (7%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCP 77
LCVG D D + C PG Q S+ + CS PC G + C DL +C +C
Sbjct: 326 LCVGG--ADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGL-CLDLGHA-LRC-RCR 380
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKP 135
+GF G E C C G +C E +C SC G+ GR C+ D A +P
Sbjct: 381 AGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRC-SCALGF--GGRDCRERADPCAARP 437
Query: 136 CGRERRC 142
C RC
Sbjct: 438 CAHGGRC 444
Score = 46.0 bits (104), Expect = 5e-04
Identities = 37/129 (28%), Positives = 54/129 (41%), Gaps = 17/129 (13%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSC---EETQ 107
C NPC G C + P ++C CP GF+G E ++C CF G C +
Sbjct: 278 CDGNPCANGG-SCSETPRS-FEC-TCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPD 334
Query: 108 YGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGY 165
C CP G+ G C+ D + +PC C+ + C C +G+ G
Sbjct: 335 SAYIC-HCPPGF--QGSNCEKRVDRCSLQPCRNGGLCLDLGHA--LRCR-CRAGFA--GP 386
Query: 166 TCV-DMDEC 173
C D+D+C
Sbjct: 387 RCEHDLDDC 395
>AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein.
Length = 502
Score = 58.8 bits (136), Expect = 7e-08
Identities = 79/284 (27%), Positives = 108/284 (38%), Gaps = 44/284 (15%)
Query: 32 RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS 91
+C PG T + R CSANPC G V P + QC CP GF G+ E
Sbjct: 141 QCSCMPG-WTGEQCQLRDFCSANPCVNGGVCLATYP--QIQC-HCPPGFEGHACERDVNE 196
Query: 92 C--RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRC--MPKST 147
C C +G SC T +C CP G G + + + C C MP+
Sbjct: 197 CFQDPGPCPKGTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKD 255
Query: 148 SPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGW 207
S ++ C CP G+ G V+ D C + C + +C++ + W
Sbjct: 256 STFHLCL-CPPGFIGPGCE-VNPDNC-VSHQCQNGGTCQD-------GLDTYTCLCPETW 305
Query: 208 RGTGNERRREHCVDVDEC-ADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYY 266
G + DVDEC A G +C G C N+ GS+ CV C +
Sbjct: 306 TGW------DCSEDVDECEAQGPPHCRNGGTCQNS-----------AGSFHCV-CVSGWG 347
Query: 267 VNTTRPCFDPDSLVKRCDP-SYCRRFNAVCGFGQKCVCNTGWTG 309
+ D D + C P S C + V F C+C G TG
Sbjct: 348 GTSCEENLD-DCIAATCAPGSTC--IDRVGSF--SCLCPPGRTG 386
Score = 54.8 bits (126), Expect = 1e-06
Identities = 48/160 (30%), Positives = 67/160 (41%), Gaps = 15/160 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA-CSANPCFGGRVPCQDLP--DGRYQCGKCP 77
G C +T F+C CP Q R C C G CQ +P D + CP
Sbjct: 207 GTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGT-CQLMPEKDSTFHLCLCP 264
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-DGRQCQHVCDAQKP- 135
GF G G E +C ++ C G +C++ C CP + G D + C+AQ P
Sbjct: 265 PGFIGPGCEVNPDNCVSHQCQNGGTCQDGLDTYTC-LCPETWTGWDCSEDVDECEAQGPP 323
Query: 136 -CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDEC 173
C C + S + C C SG W G +C + +D+C
Sbjct: 324 HCRNGGTCQNSAGS--FHCV-CVSG--WGGTSCEENLDDC 358
Score = 48.4 bits (110), Expect = 1e-04
Identities = 53/176 (30%), Positives = 72/176 (40%), Gaps = 18/176 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTS-DGQTCRTACSANP---CFGGRVPCQDLPDGRYQCGKC 76
G C D + C CP + T D C A C G CQ+ G + C C
Sbjct: 287 GGTCQDGLDTYTC-LCPETWTGWDCSEDVDECEAQGPPHCRNGGT-CQNSA-GSFHC-VC 342
Query: 77 PSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPC 136
SG+ G E C A TC G +C + C CP G G + +C +Q PC
Sbjct: 343 VSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSC-LCPPGRTGLLCHLEDMCLSQ-PC 400
Query: 137 GRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIR----PCDDLVSCRN 187
+ +C ST+P C ++G TC D+DEC + + PC+ SC N
Sbjct: 401 HGDAQC---STNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLN 453
Score = 45.6 bits (103), Expect = 7e-04
Identities = 48/182 (26%), Positives = 69/182 (37%), Gaps = 16/182 (8%)
Query: 14 TPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGRVPCQDLPDG--- 69
T L +G+ GF E C + Q C+ S + P
Sbjct: 39 TCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTP 98
Query: 70 RYQCGKCPSGFHGNGVEC-YRISCRANTCFQGVSCEETQYG-PKCGSCPTGYVGDGRQCQ 127
+ C C GF G + C + C + C G P+C SC G+ G+ Q +
Sbjct: 99 SFLC-TCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQC-SCMPGWTGEQCQLR 156
Query: 128 HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDEC-DLIRPCDDLVSC 185
C A PC C+ +T P +C CP G++ G+ C D++EC PC SC
Sbjct: 157 DFCSA-NPCVNGGVCL--ATYPQIQCH-CPPGFE--GHACERDVNECFQDPGPCPKGTSC 210
Query: 186 RN 187
N
Sbjct: 211 HN 212
Score = 43.2 bits (97), Expect = 0.004
Identities = 36/129 (27%), Positives = 44/129 (34%), Gaps = 10/129 (7%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLP-DGRYQCGKCPSG 79
G C+D F C CP +T C + PC G C P G C C G
Sbjct: 366 GSTCIDRVGSFSC-LCPPGRTGLLCHLEDMCLSQPCHGD-AQCSTNPLTGSTLC-LCQPG 422
Query: 80 FHGNGV-----ECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQK 134
+ G EC + C G SC T C CP GY G + H +
Sbjct: 423 YSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNC-LCPPGYTGSRCEADHNECLSQ 481
Query: 135 PCGRERRCM 143
PC C+
Sbjct: 482 PCHPGSTCL 490
>AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein.
Length = 1618
Score = 58.8 bits (136), Expect = 7e-08
Identities = 49/165 (29%), Positives = 69/165 (41%), Gaps = 18/165 (10%)
Query: 31 FRCERCP-GSQTSDGQTCRTACSANPC-FGGRVPCQDLPDGRYQCGKCPSGFHGNGVECY 88
+RC CP G + D + +CS+ PC GG Q+ D + C CP+GF G
Sbjct: 1032 YRCA-CPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTC-SCPTGFEGPTCGVN 1089
Query: 89 RISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA----QKPCGRERRCMP 144
C + C G C + C CP Y +G+ C+ + D PC E +C+
Sbjct: 1090 TDDCVDHACANGGVCVDGVGNYTC-QCPLQY--EGKACEQLVDLCSPDLNPCQHEAQCVG 1146
Query: 145 KSTSPYYECEGCPSGYQWNGYTCVD-MDECDLIRPCDDLVSCRNE 188
P CE C GY G C + D+C R C + C +E
Sbjct: 1147 TPDGP--RCE-CMPGYA--GDNCSENQDDCRDHR-CQNGAQCMDE 1185
Score = 54.8 bits (126), Expect = 1e-06
Identities = 48/157 (30%), Positives = 65/157 (41%), Gaps = 17/157 (10%)
Query: 36 CPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRAN 95
C G T Q C ++PC + C + P Y+C CPSG+ G E SC +
Sbjct: 998 CQGPPTLAVQAKCDLCLSSPC-QNQGTCHNDPLEVYRCA-CPSGYKGRDCEVSLDSCSSG 1055
Query: 96 TCFQGVSC--EETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKSTSPYY 151
C G +C +E + P SCPTG+ +G C D C C+ + Y
Sbjct: 1056 PCENGGTCHAQEGEDAPFTCSCPTGF--EGPTCGVNTDDCVDHACANGGVCVDGVGN--Y 1111
Query: 152 ECEGCPSGYQWNGYTC---VDMDECDLIRPCDDLVSC 185
C+ CP Q+ G C VD+ DL PC C
Sbjct: 1112 TCQ-CP--LQYEGKACEQLVDLCSPDL-NPCQHEAQC 1144
Score = 37.1 bits (82), Expect = 0.25
Identities = 29/105 (27%), Positives = 39/105 (37%), Gaps = 10/105 (9%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHG 82
+CV T G RCE PG + + C + C G C D + Y C C G+ G
Sbjct: 1143 QCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNG-AQCMDEVNS-YSC-LCAEGYSG 1199
Query: 83 NGVE------CYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG 121
E + C C G +C + P C C G+ G
Sbjct: 1200 QLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVC-QCLPGFGG 1243
>AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein
protein.
Length = 3574
Score = 58.4 bits (135), Expect = 9e-08
Identities = 41/139 (29%), Positives = 61/139 (43%), Gaps = 11/139 (7%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
CVD G+RC G +T C +NPC V C+D G + C KCP GF G
Sbjct: 1284 CVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAV-CEDQVGG-FLC-KCPPGFLGT 1340
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQ-KPCGRERR 141
C + C G +C++ +C C G+ G C+ ++ + Q PC +
Sbjct: 1341 RCGKNVDECLSQPCKNGATCKDGANSFRC-LCAAGFTGS--HCELNINECQSNPCRNQAT 1397
Query: 142 CMPKSTSPYYECEGCPSGY 160
C+ + S Y C+ C G+
Sbjct: 1398 CVDELNS--YSCK-CQPGF 1413
Score = 57.2 bits (132), Expect = 2e-07
Identities = 53/170 (31%), Positives = 78/170 (45%), Gaps = 21/170 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRT---ACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C +G+ C CP T G C T CS PC V C+DL G + C +CPSG+
Sbjct: 1208 CQQLGRGYVC-LCPLGYT--GLKCETDIDECSPLPCLNNGV-CKDLV-GEFIC-ECPSGY 1261
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQ-KPCGR 138
G E C ++ C C + G +C +C G+V G C+ V + Q PC
Sbjct: 1262 TGQRCEENINECSSSPCLNKGICVDGVAGYRC-TCVKGFV--GLHCETEVNECQSNPCLN 1318
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C + + C+ CP G+ G C ++DEC L +PC + +C++
Sbjct: 1319 NAVCEDQVGG--FLCK-CPPGFL--GTRCGKNVDEC-LSQPCKNGATCKD 1362
Score = 34.3 bits (75), Expect = 1.7
Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 6/65 (9%)
Query: 56 CFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRANTCFQGV-SCEETQYGPKCG 113
C R+ +G+ +C CPSG + + IS C+A C QG SC + C
Sbjct: 1015 CESCRIGSYQDEEGQLECKLCPSGMYTEYIHSRNISDCKAQ-CKQGTYSCSGLE---TCE 1070
Query: 114 SCPTG 118
SCP G
Sbjct: 1071 SCPLG 1075
Score = 33.5 bits (73), Expect = 3.0
Identities = 22/66 (33%), Positives = 26/66 (39%), Gaps = 3/66 (4%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D FRC G S + C +NPC + C D + Y C KC GF
Sbjct: 1357 GATCKDGANSFRCLCAAGFTGSHCELNINECQSNPC-RNQATCVDELNS-YSC-KCQPGF 1413
Query: 81 HGNGVE 86
G E
Sbjct: 1414 SGKRCE 1419
Score = 33.1 bits (72), Expect = 4.0
Identities = 38/147 (25%), Positives = 50/147 (34%), Gaps = 14/147 (9%)
Query: 52 SANPCFGGRVPCQDLPDGRYQCGK----CPSGFHGNGVE--CYRIS-CRANT-CFQGVSC 103
SA+ + G +G Y G C NGV C + C + C + SC
Sbjct: 1705 SADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASC 1764
Query: 104 EETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKS--TSPYYECEGCPSGYQ 161
C SC Y GDG+ C + P E T C GYQ
Sbjct: 1765 LNVDGSYIC-SCVPSYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQ 1823
Query: 162 WNG---YTCVDMDECDLIRPCDDLVSC 185
G TC++ E + + P VSC
Sbjct: 1824 LMGVTKITCLESGEWNHLIPYCKAVSC 1850
Score = 32.3 bits (70), Expect = 7.0
Identities = 13/34 (38%), Positives = 18/34 (52%), Gaps = 2/34 (5%)
Query: 156 CPSGYQWNGYT--CVDMDECDLIRPCDDLVSCRN 187
C WNG + C+D+DEC + C + SC N
Sbjct: 1733 CTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLN 1766
>AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 3548
Score = 58.4 bits (135), Expect = 9e-08
Identities = 41/139 (29%), Positives = 61/139 (43%), Gaps = 11/139 (7%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
CVD G+RC G +T C +NPC V C+D G + C KCP GF G
Sbjct: 1261 CVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAV-CEDQVGG-FLC-KCPPGFLGT 1317
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQ-KPCGRERR 141
C + C G +C++ +C C G+ G C+ ++ + Q PC +
Sbjct: 1318 RCGKNVDECLSQPCKNGATCKDGANSFRC-LCAAGFTGS--HCELNINECQSNPCRNQAT 1374
Query: 142 CMPKSTSPYYECEGCPSGY 160
C+ + S Y C+ C G+
Sbjct: 1375 CVDELNS--YSCK-CQPGF 1390
Score = 57.2 bits (132), Expect = 2e-07
Identities = 53/170 (31%), Positives = 78/170 (45%), Gaps = 21/170 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRT---ACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C +G+ C CP T G C T CS PC V C+DL G + C +CPSG+
Sbjct: 1185 CQQLGRGYVC-LCPLGYT--GLKCETDIDECSPLPCLNNGV-CKDLV-GEFIC-ECPSGY 1238
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQ-KPCGR 138
G E C ++ C C + G +C +C G+V G C+ V + Q PC
Sbjct: 1239 TGQRCEENINECSSSPCLNKGICVDGVAGYRC-TCVKGFV--GLHCETEVNECQSNPCLN 1295
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C + + C+ CP G+ G C ++DEC L +PC + +C++
Sbjct: 1296 NAVCEDQVGG--FLCK-CPPGFL--GTRCGKNVDEC-LSQPCKNGATCKD 1339
Score = 33.5 bits (73), Expect = 3.0
Identities = 22/66 (33%), Positives = 26/66 (39%), Gaps = 3/66 (4%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D FRC G S + C +NPC + C D + Y C KC GF
Sbjct: 1334 GATCKDGANSFRCLCAAGFTGSHCELNINECQSNPC-RNQATCVDELNS-YSC-KCQPGF 1390
Query: 81 HGNGVE 86
G E
Sbjct: 1391 SGKRCE 1396
Score = 32.3 bits (70), Expect = 7.0
Identities = 38/147 (25%), Positives = 50/147 (34%), Gaps = 14/147 (9%)
Query: 52 SANPCFGGRVPCQDLPDGRYQCGK----CPSGFHGNGVE--CYRIS-CRANT-CFQGVSC 103
SA+ + G +G Y G C NGV C + C + C + SC
Sbjct: 1679 SADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASC 1738
Query: 104 EETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKS--TSPYYECEGCPSGYQ 161
C SC Y GDG+ C + P E T C GYQ
Sbjct: 1739 LNVDGSYIC-SCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQ 1797
Query: 162 WNG---YTCVDMDECDLIRPCDDLVSC 185
G TC++ E + + P VSC
Sbjct: 1798 LMGVTKITCLESGEWNHLIPYCKAVSC 1824
Score = 32.3 bits (70), Expect = 7.0
Identities = 13/34 (38%), Positives = 18/34 (52%), Gaps = 2/34 (5%)
Query: 156 CPSGYQWNGYT--CVDMDECDLIRPCDDLVSCRN 187
C WNG + C+D+DEC + C + SC N
Sbjct: 1707 CTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLN 1740
>AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 3548
Score = 58.4 bits (135), Expect = 9e-08
Identities = 41/139 (29%), Positives = 61/139 (43%), Gaps = 11/139 (7%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
CVD G+RC G +T C +NPC V C+D G + C KCP GF G
Sbjct: 1261 CVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAV-CEDQVGG-FLC-KCPPGFLGT 1317
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQ-KPCGRERR 141
C + C G +C++ +C C G+ G C+ ++ + Q PC +
Sbjct: 1318 RCGKNVDECLSQPCKNGATCKDGANSFRC-LCAAGFTGS--HCELNINECQSNPCRNQAT 1374
Query: 142 CMPKSTSPYYECEGCPSGY 160
C+ + S Y C+ C G+
Sbjct: 1375 CVDELNS--YSCK-CQPGF 1390
Score = 57.2 bits (132), Expect = 2e-07
Identities = 53/170 (31%), Positives = 78/170 (45%), Gaps = 21/170 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRT---ACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C +G+ C CP T G C T CS PC V C+DL G + C +CPSG+
Sbjct: 1185 CQQLGRGYVC-LCPLGYT--GLKCETDIDECSPLPCLNNGV-CKDLV-GEFIC-ECPSGY 1238
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQ-KPCGR 138
G E C ++ C C + G +C +C G+V G C+ V + Q PC
Sbjct: 1239 TGQRCEENINECSSSPCLNKGICVDGVAGYRC-TCVKGFV--GLHCETEVNECQSNPCLN 1295
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C + + C+ CP G+ G C ++DEC L +PC + +C++
Sbjct: 1296 NAVCEDQVGG--FLCK-CPPGFL--GTRCGKNVDEC-LSQPCKNGATCKD 1339
Score = 33.5 bits (73), Expect = 3.0
Identities = 22/66 (33%), Positives = 26/66 (39%), Gaps = 3/66 (4%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D FRC G S + C +NPC + C D + Y C KC GF
Sbjct: 1334 GATCKDGANSFRCLCAAGFTGSHCELNINECQSNPC-RNQATCVDELNS-YSC-KCQPGF 1390
Query: 81 HGNGVE 86
G E
Sbjct: 1391 SGKRCE 1396
Score = 32.3 bits (70), Expect = 7.0
Identities = 38/147 (25%), Positives = 50/147 (34%), Gaps = 14/147 (9%)
Query: 52 SANPCFGGRVPCQDLPDGRYQCGK----CPSGFHGNGVE--CYRIS-CRANT-CFQGVSC 103
SA+ + G +G Y G C NGV C + C + C + SC
Sbjct: 1679 SADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASC 1738
Query: 104 EETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKS--TSPYYECEGCPSGYQ 161
C SC Y GDG+ C + P E T C GYQ
Sbjct: 1739 LNVDGSYIC-SCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQ 1797
Query: 162 WNG---YTCVDMDECDLIRPCDDLVSC 185
G TC++ E + + P VSC
Sbjct: 1798 LMGVTKITCLESGEWNHLIPYCKAVSC 1824
Score = 32.3 bits (70), Expect = 7.0
Identities = 13/34 (38%), Positives = 18/34 (52%), Gaps = 2/34 (5%)
Query: 156 CPSGYQWNGYT--CVDMDECDLIRPCDDLVSCRN 187
C WNG + C+D+DEC + C + SC N
Sbjct: 1707 CTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLN 1740
>AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 3548
Score = 58.4 bits (135), Expect = 9e-08
Identities = 41/139 (29%), Positives = 61/139 (43%), Gaps = 11/139 (7%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
CVD G+RC G +T C +NPC V C+D G + C KCP GF G
Sbjct: 1261 CVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAV-CEDQVGG-FLC-KCPPGFLGT 1317
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQ-KPCGRERR 141
C + C G +C++ +C C G+ G C+ ++ + Q PC +
Sbjct: 1318 RCGKNVDECLSQPCKNGATCKDGANSFRC-LCAAGFTGS--HCELNINECQSNPCRNQAT 1374
Query: 142 CMPKSTSPYYECEGCPSGY 160
C+ + S Y C+ C G+
Sbjct: 1375 CVDELNS--YSCK-CQPGF 1390
Score = 57.2 bits (132), Expect = 2e-07
Identities = 53/170 (31%), Positives = 78/170 (45%), Gaps = 21/170 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRT---ACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C +G+ C CP T G C T CS PC V C+DL G + C +CPSG+
Sbjct: 1185 CQQLGRGYVC-LCPLGYT--GLKCETDIDECSPLPCLNNGV-CKDLV-GEFIC-ECPSGY 1238
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQ-KPCGR 138
G E C ++ C C + G +C +C G+V G C+ V + Q PC
Sbjct: 1239 TGQRCEENINECSSSPCLNKGICVDGVAGYRC-TCVKGFV--GLHCETEVNECQSNPCLN 1295
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C + + C+ CP G+ G C ++DEC L +PC + +C++
Sbjct: 1296 NAVCEDQVGG--FLCK-CPPGFL--GTRCGKNVDEC-LSQPCKNGATCKD 1339
Score = 33.5 bits (73), Expect = 3.0
Identities = 22/66 (33%), Positives = 26/66 (39%), Gaps = 3/66 (4%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D FRC G S + C +NPC + C D + Y C KC GF
Sbjct: 1334 GATCKDGANSFRCLCAAGFTGSHCELNINECQSNPC-RNQATCVDELNS-YSC-KCQPGF 1390
Query: 81 HGNGVE 86
G E
Sbjct: 1391 SGKRCE 1396
Score = 32.3 bits (70), Expect = 7.0
Identities = 38/147 (25%), Positives = 50/147 (34%), Gaps = 14/147 (9%)
Query: 52 SANPCFGGRVPCQDLPDGRYQCGK----CPSGFHGNGVE--CYRIS-CRANT-CFQGVSC 103
SA+ + G +G Y G C NGV C + C + C + SC
Sbjct: 1679 SADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASC 1738
Query: 104 EETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKS--TSPYYECEGCPSGYQ 161
C SC Y GDG+ C + P E T C GYQ
Sbjct: 1739 LNVDGSYIC-SCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQ 1797
Query: 162 WNG---YTCVDMDECDLIRPCDDLVSC 185
G TC++ E + + P VSC
Sbjct: 1798 LMGVTKITCLESGEWNHLIPYCKAVSC 1824
Score = 32.3 bits (70), Expect = 7.0
Identities = 13/34 (38%), Positives = 18/34 (52%), Gaps = 2/34 (5%)
Query: 156 CPSGYQWNGYT--CVDMDECDLIRPCDDLVSCRN 187
C WNG + C+D+DEC + C + SC N
Sbjct: 1707 CTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLN 1740
>AK092062-1|BAC03798.1| 880|Homo sapiens protein ( Homo sapiens
cDNA FLJ34743 fis, clone MESAN2009019, moderately
similar to CEGP1 protein. ).
Length = 880
Score = 58.4 bits (135), Expect = 9e-08
Identities = 87/307 (28%), Positives = 125/307 (40%), Gaps = 66/307 (21%)
Query: 63 CQDLPDGRYQCGKCPSGFH--GNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYV 120
C++ P G C +C GF N +C +++C +C++T+ GP+CG C +V
Sbjct: 43 CRETPKGGIAC-ECRPGFELTKNQRDC-KLTCNYGNGGCQHTCDDTEQGPRCG-CHIKFV 99
Query: 121 --GDGRQC-------QHV---CDAQKPC-----GRERRCMPKSTSPYYECEGCPSGY--Q 161
DG+ C QH+ + + C G + +C +T + C CP G+ Q
Sbjct: 100 LHTDGKTCIGERRLEQHIPTQAVSNETCAVNNGGCDSKCHDAATGVH--CT-CPVGFMLQ 156
Query: 162 WNGYTCVDMDECDLIR-PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCV 220
+ TC D+DEC L CD + CRN +G++ NER +C
Sbjct: 157 PDRKTCKDIDECRLNNGGCDHI--CRN-------TVGSFECSCKKGYKLLINER---NCQ 204
Query: 221 DVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLV 280
D+DEC+ R C +CVNTP GS+ C+ C Y + C D D
Sbjct: 205 DIDECSFDR-TC--DHICVNTP-----------GSFQCL-CHRGYLLYGITHCGDVDEC- 248
Query: 281 KRCDPSYCRRFNAVCGFGQ-KCVCNTG---WTGNGTVCGLDRDLDGHP---DEQLPCNEP 333
+ C RF + G +C C G NG C G P L CN
Sbjct: 249 -SINRGGC-RFGCINTPGSYQCTCPAGQGRLHWNGKDCTEPLKCQGSPGASKAMLSCNRS 306
Query: 334 RCKKDNC 340
KKD C
Sbjct: 307 G-KKDTC 312
>AK075302-1|BAC11535.1| 587|Homo sapiens protein ( Homo sapiens
cDNA FLJ90821 fis, clone Y79AA1001328, highly similar to
Delta-like protein 3 precursor. ).
Length = 587
Score = 58.4 bits (135), Expect = 9e-08
Identities = 43/127 (33%), Positives = 55/127 (43%), Gaps = 10/127 (7%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCP 77
LCVG D D + C PG Q S+ + CS PC G + C DL +C +C
Sbjct: 326 LCVGG--ADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGL-CLDLGHA-LRC-RCR 380
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKP 135
+GF G E C C G +C E +C SC G+ GR C+ D A +P
Sbjct: 381 AGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRC-SCALGF--GGRDCRERADPCAVRP 437
Query: 136 CGRERRC 142
C RC
Sbjct: 438 CAHGGRC 444
Score = 46.0 bits (104), Expect = 5e-04
Identities = 37/129 (28%), Positives = 54/129 (41%), Gaps = 17/129 (13%)
Query: 51 CSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSC---EETQ 107
C NPC G C + P ++C CP GF+G E ++C CF G C +
Sbjct: 278 CDGNPCANGG-SCSETPRS-FEC-TCPRGFYGLRCEVSGVTCANGPCFNGGLCVGGADPD 334
Query: 108 YGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGY 165
C CP G+ G C+ D + +PC C+ + C C +G+ G
Sbjct: 335 SAYIC-HCPPGF--QGSNCEKRVDRCSLQPCRNGGLCLDLGHA--LRCR-CRAGFA--GP 386
Query: 166 TCV-DMDEC 173
C D+D+C
Sbjct: 387 RCEHDLDDC 395
>AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens cDNA
FLJ14964 fis, clone PLACE4000581, moderately similar to
FIBROPELLIN I PRECURSOR. ).
Length = 1316
Score = 58.4 bits (135), Expect = 9e-08
Identities = 41/139 (29%), Positives = 61/139 (43%), Gaps = 11/139 (7%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
CVD G+RC G +T C +NPC V C+D G + C KCP GF G
Sbjct: 1051 CVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAV-CEDQVGG-FLC-KCPPGFLGT 1107
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQ-KPCGRERR 141
C + C G +C++ +C C G+ G C+ ++ + Q PC +
Sbjct: 1108 RCGKNVDECLSQPCKNGATCKDGANSFRC-LCAAGFTGS--HCELNINECQSNPCRNQAT 1164
Query: 142 CMPKSTSPYYECEGCPSGY 160
C+ + S Y C+ C G+
Sbjct: 1165 CVDELNS--YSCK-CQPGF 1180
Score = 57.2 bits (132), Expect = 2e-07
Identities = 53/170 (31%), Positives = 78/170 (45%), Gaps = 21/170 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRT---ACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C +G+ C CP T G C T CS PC V C+DL G + C +CPSG+
Sbjct: 975 CQQLGRGYVC-LCPLGYT--GLKCETDIDECSPLPCLNNGV-CKDLV-GEFIC-ECPSGY 1028
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQ-KPCGR 138
G E C ++ C C + G +C +C G+V G C+ V + Q PC
Sbjct: 1029 TGQRCEENINECSSSPCLNKGICVDGVAGYRC-TCVKGFV--GLHCETEVNECQSNPCLN 1085
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C + + C+ CP G+ G C ++DEC L +PC + +C++
Sbjct: 1086 NAVCEDQVGG--FLCK-CPPGFL--GTRCGKNVDEC-LSQPCKNGATCKD 1129
Score = 34.3 bits (75), Expect = 1.7
Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 6/65 (9%)
Query: 56 CFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRANTCFQGV-SCEETQYGPKCG 113
C R+ +G+ +C CPSG + + IS C+A C QG SC + C
Sbjct: 782 CESCRIGSYQDEEGQLECKLCPSGMYTEYIHSRNISDCKAQ-CKQGTYSCSGLE---TCE 837
Query: 114 SCPTG 118
SCP G
Sbjct: 838 SCPLG 842
Score = 33.5 bits (73), Expect = 3.0
Identities = 22/66 (33%), Positives = 26/66 (39%), Gaps = 3/66 (4%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D FRC G S + C +NPC + C D + Y C KC GF
Sbjct: 1124 GATCKDGANSFRCLCAAGFTGSHCELNINECQSNPC-RNQATCVDELNS-YSC-KCQPGF 1180
Query: 81 HGNGVE 86
G E
Sbjct: 1181 SGKRCE 1186
>AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein.
Length = 3574
Score = 58.4 bits (135), Expect = 9e-08
Identities = 41/139 (29%), Positives = 61/139 (43%), Gaps = 11/139 (7%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
CVD G+RC G +T C +NPC V C+D G + C KCP GF G
Sbjct: 1284 CVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAV-CEDQVGG-FLC-KCPPGFLGT 1340
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQ-KPCGRERR 141
C + C G +C++ +C C G+ G C+ ++ + Q PC +
Sbjct: 1341 RCGKNVDECLSQPCKNGATCKDGANSFRC-LCAAGFTGS--HCELNINECQSNPCRNQAT 1397
Query: 142 CMPKSTSPYYECEGCPSGY 160
C+ + S Y C+ C G+
Sbjct: 1398 CVDELNS--YSCK-CQPGF 1413
Score = 57.2 bits (132), Expect = 2e-07
Identities = 53/170 (31%), Positives = 78/170 (45%), Gaps = 21/170 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRT---ACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
C +G+ C CP T G C T CS PC V C+DL G + C +CPSG+
Sbjct: 1208 CQQLGRGYVC-LCPLGYT--GLKCETDIDECSPLPCLNNGV-CKDLV-GEFIC-ECPSGY 1261
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQ-KPCGR 138
G E C ++ C C + G +C +C G+V G C+ V + Q PC
Sbjct: 1262 TGQRCEENINECSSSPCLNKGICVDGVAGYRC-TCVKGFV--GLHCETEVNECQSNPCLN 1318
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRN 187
C + + C+ CP G+ G C ++DEC L +PC + +C++
Sbjct: 1319 NAVCEDQVGG--FLCK-CPPGFL--GTRCGKNVDEC-LSQPCKNGATCKD 1362
Score = 34.3 bits (75), Expect = 1.7
Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 6/65 (9%)
Query: 56 CFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRANTCFQGV-SCEETQYGPKCG 113
C R+ +G+ +C CPSG + + IS C+A C QG SC + C
Sbjct: 1015 CESCRIGSYQDEEGQLECKLCPSGMYTEYIHSRNISDCKAQ-CKQGTYSCSGLE---TCE 1070
Query: 114 SCPTG 118
SCP G
Sbjct: 1071 SCPLG 1075
Score = 33.5 bits (73), Expect = 3.0
Identities = 22/66 (33%), Positives = 26/66 (39%), Gaps = 3/66 (4%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D FRC G S + C +NPC + C D + Y C KC GF
Sbjct: 1357 GATCKDGANSFRCLCAAGFTGSHCELNINECQSNPC-RNQATCVDELNS-YSC-KCQPGF 1413
Query: 81 HGNGVE 86
G E
Sbjct: 1414 SGKRCE 1419
Score = 33.1 bits (72), Expect = 4.0
Identities = 38/147 (25%), Positives = 50/147 (34%), Gaps = 14/147 (9%)
Query: 52 SANPCFGGRVPCQDLPDGRYQCGK----CPSGFHGNGVE--CYRIS-CRANT-CFQGVSC 103
SA+ + G +G Y G C NGV C + C + C + SC
Sbjct: 1705 SADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASC 1764
Query: 104 EETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKS--TSPYYECEGCPSGYQ 161
C SC Y GDG+ C + P E T C GYQ
Sbjct: 1765 LNVDGSYIC-SCVPSYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQ 1823
Query: 162 WNG---YTCVDMDECDLIRPCDDLVSC 185
G TC++ E + + P VSC
Sbjct: 1824 LMGVTKITCLESGEWNHLIPYCKAVSC 1850
Score = 32.3 bits (70), Expect = 7.0
Identities = 13/34 (38%), Positives = 18/34 (52%), Gaps = 2/34 (5%)
Query: 156 CPSGYQWNGYT--CVDMDECDLIRPCDDLVSCRN 187
C WNG + C+D+DEC + C + SC N
Sbjct: 1733 CTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLN 1766
>BC038587-1|AAH38587.1| 553|Homo sapiens EGF-like-domain, multiple
6 protein.
Length = 553
Score = 57.6 bits (133), Expect = 2e-07
Identities = 71/230 (30%), Positives = 92/230 (40%), Gaps = 39/230 (16%)
Query: 92 CRANTCFQGVSCEETQYGPKCGSCPTGYVGDG-RQCQHVCDAQ-KPCGRERRCMPKSTSP 149
C A TC G E GP C GY G Q + C + +PC + RC+ +T
Sbjct: 61 CEA-TCEPGCKFGEC-VGPNKCRCFPGYTGKTCSQDVNECGMKPRPC--QHRCV--NTHG 114
Query: 150 YYECEGCPSGYQ-WNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWR 208
Y+C C SG+ TCV+ C +I C SC + E S G R
Sbjct: 115 SYKCF-CLSGHMLMPDATCVNSRTCAMIN-CQ--YSCEDTEEGPQCLCP------SSGLR 164
Query: 209 GTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGH--YY 266
N R C+D+DECA G+ CP R CVNT GSY C G Y
Sbjct: 165 LAPNGR---DCLDIDECASGKVICPYNRRCVNT-----------FGSYYCKCHIGFELQY 210
Query: 267 VNTTRPCFDPD--SLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
++ C D + ++ + FN F KC C G+ GNG C
Sbjct: 211 ISGRYDCIDINECTMDSHTCSHHANCFNTQGSF--KCKCKQGYKGNGLRC 258
Score = 36.7 bits (81), Expect = 0.33
Identities = 42/165 (25%), Positives = 61/165 (36%), Gaps = 24/165 (14%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTC--RTACSANPCFGGRVPCQDLPDGRYQCGKCPSG- 79
RCV+T ++C G TC C+ C + C+D +G QC CPS
Sbjct: 108 RCVNTHGSYKCFCLSGHMLMPDATCVNSRTCAMINC---QYSCEDTEEGP-QC-LCPSSG 162
Query: 80 --FHGNGVECYRI-SCRAN--TCFQGVSCEETQYGPKCGSCPTG----YVGDGRQCQHVC 130
NG +C I C + C C T +G C G Y+ C +
Sbjct: 163 LRLAPNGRDCLDIDECASGKVICPYNRRCVNT-FGSYYCKCHIGFELQYISGRYDCIDIN 221
Query: 131 DA---QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDE 172
+ C C +T ++C+ C GY+ NG C + E
Sbjct: 222 ECTMDSHTCSHHANCF--NTQGSFKCK-CKQGYKGNGLRCSAIPE 263
>AY358333-1|AAQ88699.1| 338|Homo sapiens EGFL6 protein.
Length = 338
Score = 57.6 bits (133), Expect = 2e-07
Identities = 71/230 (30%), Positives = 92/230 (40%), Gaps = 39/230 (16%)
Query: 92 CRANTCFQGVSCEETQYGPKCGSCPTGYVGDG-RQCQHVCDAQ-KPCGRERRCMPKSTSP 149
C A TC G E GP C GY G Q + C + +PC + RC+ +T
Sbjct: 61 CEA-TCEPGCKFGEC-VGPNKCRCFPGYTGKTCSQDVNECGMKPRPC--QHRCV--NTHG 114
Query: 150 YYECEGCPSGYQ-WNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWR 208
Y+C C SG+ TCV+ C +I C SC + E S G R
Sbjct: 115 SYKCF-CLSGHMLMPDATCVNSRTCAMIN-CQ--YSCEDTEEGPQCLCP------SSGLR 164
Query: 209 GTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGH--YY 266
N R C+D+DECA G+ CP R CVNT GSY C G Y
Sbjct: 165 LAPNGR---DCLDIDECASGKVICPYNRRCVNT-----------FGSYYCKCHIGFELQY 210
Query: 267 VNTTRPCFDPD--SLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
++ C D + ++ + FN F KC C G+ GNG C
Sbjct: 211 ISGRYDCIDINECTMDSHTCSHHANCFNTQGSF--KCKCKQGYKGNGLRC 258
Score = 36.7 bits (81), Expect = 0.33
Identities = 42/165 (25%), Positives = 61/165 (36%), Gaps = 24/165 (14%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTC--RTACSANPCFGGRVPCQDLPDGRYQCGKCPSG- 79
RCV+T ++C G TC C+ C + C+D +G QC CPS
Sbjct: 108 RCVNTHGSYKCFCLSGHMLMPDATCVNSRTCAMINC---QYSCEDTEEGP-QC-LCPSSG 162
Query: 80 --FHGNGVECYRI-SCRAN--TCFQGVSCEETQYGPKCGSCPTG----YVGDGRQCQHVC 130
NG +C I C + C C T +G C G Y+ C +
Sbjct: 163 LRLAPNGRDCLDIDECASGKVICPYNRRCVNT-FGSYYCKCHIGFELQYISGRYDCIDIN 221
Query: 131 DA---QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDE 172
+ C C +T ++C+ C GY+ NG C + E
Sbjct: 222 ECTMDSHTCSHHANCF--NTQGSFKCK-CKQGYKGNGLRCSAIPE 263
>AK075214-1|BAC11477.1| 553|Homo sapiens protein ( Homo sapiens
cDNA FLJ90733 fis, clone PLACE1010251, highly similar to
Epidermal growth factor-like protein 6 precursor. ).
Length = 553
Score = 57.6 bits (133), Expect = 2e-07
Identities = 71/230 (30%), Positives = 92/230 (40%), Gaps = 39/230 (16%)
Query: 92 CRANTCFQGVSCEETQYGPKCGSCPTGYVGDG-RQCQHVCDAQ-KPCGRERRCMPKSTSP 149
C A TC G E GP C GY G Q + C + +PC + RC+ +T
Sbjct: 61 CEA-TCEPGCKFGEC-VGPNKCRCFPGYTGKTCSQDVNECGMKPRPC--QHRCV--NTHG 114
Query: 150 YYECEGCPSGYQ-WNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWR 208
Y+C C SG+ TCV+ C +I C SC + E S G R
Sbjct: 115 SYKCF-CLSGHMLMPDATCVNSRTCAMIN-CQ--YSCEDTEEGPQCLCP------SSGLR 164
Query: 209 GTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGH--YY 266
N R C+D+DECA G+ CP R CVNT GSY C G Y
Sbjct: 165 LAPNGR---DCLDIDECASGKVICPYNRRCVNT-----------FGSYYCKCHIGFELQY 210
Query: 267 VNTTRPCFDPD--SLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
++ C D + ++ + FN F KC C G+ GNG C
Sbjct: 211 ISGRYDCIDINECTMDSHTCSHHANCFNTQGSF--KCKCKQGYKGNGLRC 258
Score = 36.7 bits (81), Expect = 0.33
Identities = 42/165 (25%), Positives = 61/165 (36%), Gaps = 24/165 (14%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTC--RTACSANPCFGGRVPCQDLPDGRYQCGKCPSG- 79
RCV+T ++C G TC C+ C + C+D +G QC CPS
Sbjct: 108 RCVNTHGSYKCFCLSGHMLMPDATCVNSRTCAMINC---QYSCEDTEEGP-QC-LCPSSG 162
Query: 80 --FHGNGVECYRI-SCRAN--TCFQGVSCEETQYGPKCGSCPTG----YVGDGRQCQHVC 130
NG +C I C + C C T +G C G Y+ C +
Sbjct: 163 LRLAPNGRDCLDIDECASGKVICPYNRRCVNT-FGSYYCKCHIGFELQYISGRYDCIDIN 221
Query: 131 DA---QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDE 172
+ C C +T ++C+ C GY+ NG C + E
Sbjct: 222 ECTMDSHTCSHHANCF--NTQGSFKCK-CKQGYKGNGLRCSAIPE 263
>AJ245671-1|CAB92132.1| 554|Homo sapiens hypothetical protein
protein.
Length = 554
Score = 57.6 bits (133), Expect = 2e-07
Identities = 71/230 (30%), Positives = 92/230 (40%), Gaps = 39/230 (16%)
Query: 92 CRANTCFQGVSCEETQYGPKCGSCPTGYVGDG-RQCQHVCDAQ-KPCGRERRCMPKSTSP 149
C A TC G E GP C GY G Q + C + +PC + RC+ +T
Sbjct: 61 CEA-TCEPGCKFGEC-VGPNKCRCFPGYTGKTCSQDVNECGMKPRPC--QHRCV--NTHG 114
Query: 150 YYECEGCPSGYQ-WNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWR 208
Y+C C SG+ TCV+ C +I C SC + E S G R
Sbjct: 115 SYKCF-CLSGHMLMPDATCVNSRTCAMIN-CQ--YSCEDTEEGPQCLCP------SSGLR 164
Query: 209 GTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGH--YY 266
N R C+D+DECA G+ CP R CVNT GSY C G Y
Sbjct: 165 LAPNGR---DCLDIDECASGKVICPYNRRCVNT-----------FGSYYCKCHIGFELQY 210
Query: 267 VNTTRPCFDPD--SLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
++ C D + ++ + FN F KC C G+ GNG C
Sbjct: 211 ISGRYDCIDINECTMDSHTCSHHANCFNTQGSF--KCKCKQGYKGNGLRC 258
Score = 36.7 bits (81), Expect = 0.33
Identities = 42/165 (25%), Positives = 61/165 (36%), Gaps = 24/165 (14%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTC--RTACSANPCFGGRVPCQDLPDGRYQCGKCPSG- 79
RCV+T ++C G TC C+ C + C+D +G QC CPS
Sbjct: 108 RCVNTHGSYKCFCLSGHMLMPDATCVNSRTCAMINC---QYSCEDTEEGP-QC-LCPSSG 162
Query: 80 --FHGNGVECYRI-SCRAN--TCFQGVSCEETQYGPKCGSCPTG----YVGDGRQCQHVC 130
NG +C I C + C C T +G C G Y+ C +
Sbjct: 163 LRLAPNGRDCLDIDECASGKVICPYNRRCVNT-FGSYYCKCHIGFELQYISGRYDCIDIN 221
Query: 131 DA---QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDE 172
+ C C +T ++C+ C GY+ NG C + E
Sbjct: 222 ECTMDSHTCSHHANCF--NTQGSFKCK-CKQGYKGNGLRCSAIPE 263
>AF186084-1|AAF27812.1| 553|Homo sapiens epidermal growth factor
repeat containing protein protein.
Length = 553
Score = 57.6 bits (133), Expect = 2e-07
Identities = 71/230 (30%), Positives = 92/230 (40%), Gaps = 39/230 (16%)
Query: 92 CRANTCFQGVSCEETQYGPKCGSCPTGYVGDG-RQCQHVCDAQ-KPCGRERRCMPKSTSP 149
C A TC G E GP C GY G Q + C + +PC + RC+ +T
Sbjct: 61 CEA-TCEPGCKFGEC-VGPNKCRCFPGYTGKTCSQDVNECGMKPRPC--QHRCV--NTHG 114
Query: 150 YYECEGCPSGYQ-WNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWR 208
Y+C C SG+ TCV+ C +I C SC + E S G R
Sbjct: 115 SYKCF-CLSGHMLMPDATCVNSRTCAMIN-CQ--YSCEDTEEGPQCLCP------SSGLR 164
Query: 209 GTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGH--YY 266
N R C+D+DECA G+ CP R CVNT GSY C G Y
Sbjct: 165 LAPNGR---DCLDIDECASGKVICPYNRRCVNT-----------FGSYYCKCHIGFELQY 210
Query: 267 VNTTRPCFDPD--SLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
++ C D + ++ + FN F KC C G+ GNG C
Sbjct: 211 ISGRYDCIDINECTMDSHTCSHHANCFNTQGSF--KCKCKQGYKGNGLRC 258
Score = 36.7 bits (81), Expect = 0.33
Identities = 42/165 (25%), Positives = 61/165 (36%), Gaps = 24/165 (14%)
Query: 23 RCVDTDQGFRCERCPGSQTSDGQTC--RTACSANPCFGGRVPCQDLPDGRYQCGKCPSG- 79
RCV+T ++C G TC C+ C + C+D +G QC CPS
Sbjct: 108 RCVNTHGSYKCFCLSGHMLMPDATCVNSRTCAMINC---QYSCEDTEEGP-QC-LCPSSG 162
Query: 80 --FHGNGVECYRI-SCRAN--TCFQGVSCEETQYGPKCGSCPTG----YVGDGRQCQHVC 130
NG +C I C + C C T +G C G Y+ C +
Sbjct: 163 LRLAPNGRDCLDIDECASGKVICPYNRRCVNT-FGSYYCKCHIGFELQYISGRYDCIDIN 221
Query: 131 DA---QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDE 172
+ C C +T ++C+ C GY+ NG C + E
Sbjct: 222 ECTMDSHTCSHHANCF--NTQGSFKCK-CKQGYKGNGLRCSAIPE 263
>DQ309460-1|ABC26875.1| 231|Homo sapiens delta-like 1 protein.
Length = 231
Score = 57.2 bits (132), Expect = 2e-07
Identities = 44/148 (29%), Positives = 54/148 (36%), Gaps = 8/148 (5%)
Query: 24 CVDTDQG-FRCERCPGSQTSDGQTCRTACSAN--PCFGGRVPCQDLPDGRYQCGKCPSGF 80
CV D G + C PG D Q C N PC G D + CP GF
Sbjct: 16 CVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGF 75
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
GN E SC N C C + +C CP G++ A PC
Sbjct: 76 SGNFCEIVANSCTPNPCENDGVCTDIGGDFRC-RCPAGFIDKTCSRPVTNCASSPCQNGG 134
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTCV 168
C+ + T YEC P ++ G TCV
Sbjct: 135 TCL-QHTQVSYECLCKP---EFTGLTCV 158
>BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein.
Length = 647
Score = 57.2 bits (132), Expect = 2e-07
Identities = 47/168 (27%), Positives = 67/168 (39%), Gaps = 15/168 (8%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C++T F C PG S + C + PC G C DL + C CP G
Sbjct: 449 GGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGST-CLDLL-ATFHC-LCPPGL 505
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGR 138
G E C + C C + G +C C G+ G +C+ D PC
Sbjct: 506 EGQLCEVETNECASAPCLNHADCHDLLNGFQC-ICLPGF--SGTRCEEDIDECRSSPCAN 562
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSC 185
+C + + + C+ C G++ G C ++DEC L PC SC
Sbjct: 563 GGQCQDQPGA--FHCK-CLPGFE--GPRCQTEVDEC-LSDPCPVGASC 604
Score = 56.8 bits (131), Expect = 3e-07
Identities = 79/285 (27%), Positives = 108/285 (37%), Gaps = 46/285 (16%)
Query: 32 RCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS 91
+C PG T + R CSANPC G V P + QC CP GF G+ E
Sbjct: 142 QCSCMPG-WTGEQCQLRDFCSANPCVNGGVCLATYP--QIQC-HCPPGFEGHACERDVNE 197
Query: 92 C--RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRC--MPKST 147
C C +G SC T +C CP G G + + + C C MP+
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKD 256
Query: 148 SPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQG 206
S ++ C CP G+ G C V+ D C + C + +C++ +
Sbjct: 257 STFHLCL-CPPGF--IGPDCEVNPDNC-VSHQCQNGGTCQD-------GLDTYTCLCPET 305
Query: 207 WRGTGNERRREHCVDVDEC-ADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHY 265
W G + DVDEC G +C G C N+ GS+ CV C +
Sbjct: 306 WTGW------DCSEDVDECETQGPPHCRNGGTCQNS-----------AGSFHCV-CVSGW 347
Query: 266 YVNTTRPCFDPDSLVKRCDP-SYCRRFNAVCGFGQKCVCNTGWTG 309
+ D D + C P S C + V F C+C G TG
Sbjct: 348 GGTSCEENLD-DCIAATCAPGSTC--IDRVGSF--SCLCPPGRTG 387
Score = 50.4 bits (115), Expect = 2e-05
Identities = 46/160 (28%), Positives = 65/160 (40%), Gaps = 15/160 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA-CSANPCFGGRVPCQDLP--DGRYQCGKCP 77
G C +T F+C CP Q R C C G CQ +P D + CP
Sbjct: 208 GTSCHNTLGSFQC-LCPVGQEGPRCELRAGPCPPRGCSNGGT-CQLMPEKDSTFHLCLCP 265
Query: 78 SGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG-DGRQCQHVCDAQKP- 135
GF G E +C ++ C G +C++ C CP + G D + C+ Q P
Sbjct: 266 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTC-LCPETWTGWDCSEDVDECETQGPP 324
Query: 136 -CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDEC 173
C C + S + C C SG W G +C + +D+C
Sbjct: 325 HCRNGGTCQNSAGS--FHCV-CVSG--WGGTSCEENLDDC 359
Score = 49.6 bits (113), Expect = 4e-05
Identities = 53/177 (29%), Positives = 73/177 (41%), Gaps = 20/177 (11%)
Query: 21 GERCVDTDQGFRCERCPGSQTS-----DGQTCRTACSANPCFGGRVPCQDLPDGRYQCGK 75
G C D + C CP + T D C T + GG CQ+ G + C
Sbjct: 288 GGTCQDGLDTYTC-LCPETWTGWDCSEDVDECETQGPPHCRNGGT--CQNSA-GSFHC-V 342
Query: 76 CPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP 135
C SG+ G E C A TC G +C + C CP G G + +C +Q P
Sbjct: 343 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSC-LCPPGRTGLLCHLEDMCLSQ-P 400
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIR----PCDDLVSCRN 187
C + +C ST+P C ++G TC D+DEC + + PC+ SC N
Sbjct: 401 CHGDAQC---STNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLN 454
Score = 45.6 bits (103), Expect = 7e-04
Identities = 48/182 (26%), Positives = 69/182 (37%), Gaps = 16/182 (8%)
Query: 14 TPFKLCVGERCVDTDQGFRCERCP-GSQTSDGQTCRTACSANPCFGGRVPCQDLPDG--- 69
T L +G+ GF E C + Q C+ S + P
Sbjct: 40 TCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTP 99
Query: 70 RYQCGKCPSGFHGNGVEC-YRISCRANTCFQGVSCEETQYG-PKCGSCPTGYVGDGRQCQ 127
+ C C GF G + C + C + C G P+C SC G+ G+ Q +
Sbjct: 100 SFLC-TCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQC-SCMPGWTGEQCQLR 157
Query: 128 HVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDEC-DLIRPCDDLVSC 185
C A PC C+ +T P +C CP G++ G+ C D++EC PC SC
Sbjct: 158 DFCSA-NPCVNGGVCL--ATYPQIQCH-CPPGFE--GHACERDVNECFQDPGPCPKGTSC 211
Query: 186 RN 187
N
Sbjct: 212 HN 213
Score = 42.3 bits (95), Expect = 0.007
Identities = 25/63 (39%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G +C D F C+ PG + QT C ++PC G C DLP G + C CPSGF
Sbjct: 563 GGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVG-ASCLDLP-GAFFC-LCPSGF 619
Query: 81 HGN 83
G+
Sbjct: 620 TGS 622
>BC050675-1|AAH50675.1| 353|Homo sapiens cysteine-rich with
EGF-like domains 2 protein.
Length = 353
Score = 57.2 bits (132), Expect = 2e-07
Identities = 56/185 (30%), Positives = 66/185 (35%), Gaps = 30/185 (16%)
Query: 103 CEETQYGPKCGSCPTGYVGDGRQCQH-VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ 161
C GP C C GY R H +C A C + C S +C C G+
Sbjct: 168 CHMGYQGPLCTDCMDGYFSSLRNETHSICTA---C--DESCKTCSGLTNRDCGECEVGWV 222
Query: 162 WNGYTCVDMDECDLIRP-CDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERR----- 215
+ CVD+DEC P C C+N G G GN +
Sbjct: 223 LDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTG-EGPGNCKECISGY 281
Query: 216 -REH--CVDVDECADGRANCPR-GRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTR 271
REH C DVDECA C R C NTP GSY+CV G + T
Sbjct: 282 AREHGQCADVDECALAEKTCVRKNENCYNTP-----------GSYVCVCPDG--FEGTED 328
Query: 272 PCFDP 276
C P
Sbjct: 329 ACVPP 333
>BC014015-1|AAH14015.1| 383|Homo sapiens delta-like 1 homolog
(Drosophila) protein.
Length = 383
Score = 57.2 bits (132), Expect = 2e-07
Identities = 44/148 (29%), Positives = 54/148 (36%), Gaps = 8/148 (5%)
Query: 24 CVDTDQG-FRCERCPGSQTSDGQTCRTACSAN--PCFGGRVPCQDLPDGRYQCGKCPSGF 80
CV D G + C PG D Q C N PC G D + CP GF
Sbjct: 103 CVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGF 162
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
GN E SC N C C + +C CP G++ A PC
Sbjct: 163 SGNFCEIVANSCTPNPCENDGVCTDIGGDFRC-RCPAGFIDKTCSRPVTNCASSPCQNGG 221
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTCV 168
C+ + T YEC P ++ G TCV
Sbjct: 222 TCL-QHTQVSYECLCKP---EFTGLTCV 245
>BC013197-1|AAH13197.1| 383|Homo sapiens delta-like 1 homolog
(Drosophila) protein.
Length = 383
Score = 57.2 bits (132), Expect = 2e-07
Identities = 44/148 (29%), Positives = 54/148 (36%), Gaps = 8/148 (5%)
Query: 24 CVDTDQG-FRCERCPGSQTSDGQTCRTACSAN--PCFGGRVPCQDLPDGRYQCGKCPSGF 80
CV D G + C PG D Q C N PC G D + CP GF
Sbjct: 103 CVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGF 162
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
GN E SC N C C + +C CP G++ A PC
Sbjct: 163 SGNFCEIVANSCTPNPCENDGVCTDIGGDFRC-RCPAGFIDKTCSRPVTNCASSPCQNGG 221
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTCV 168
C+ + T YEC P ++ G TCV
Sbjct: 222 TCL-QHTQVSYECLCKP---EFTGLTCV 245
>BC007741-1|AAH07741.1| 383|Homo sapiens delta-like 1 homolog
(Drosophila) protein.
Length = 383
Score = 57.2 bits (132), Expect = 2e-07
Identities = 44/148 (29%), Positives = 54/148 (36%), Gaps = 8/148 (5%)
Query: 24 CVDTDQG-FRCERCPGSQTSDGQTCRTACSAN--PCFGGRVPCQDLPDGRYQCGKCPSGF 80
CV D G + C PG D Q C N PC G D + CP GF
Sbjct: 103 CVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGF 162
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
GN E SC N C C + +C CP G++ A PC
Sbjct: 163 SGNFCEIVANSCTPNPCENDGVCTDIGGDFRC-RCPAGFIDKTCSRPVTNCASSPCQNGG 221
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTCV 168
C+ + T YEC P ++ G TCV
Sbjct: 222 TCL-QHTQVSYECLCKP---EFTGLTCV 245
>AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein.
Length = 1523
Score = 56.8 bits (131), Expect = 3e-07
Identities = 47/150 (31%), Positives = 57/150 (38%), Gaps = 17/150 (11%)
Query: 31 FRCERCPGSQTSDGQTCR-TACSANPC-FGGRVPCQDLPDGRYQCGKCPSGFHGNGVECY 88
+RC CP S T C NPC GG D + C CP GF G E
Sbjct: 939 YRCA-CPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCS-CPLGFEGQRCEIN 996
Query: 89 RISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP----CGRERRCMP 144
C N C +C + C CP Y G+ C V D P C E +C+P
Sbjct: 997 PDDCEDNDCENNATCVDGINNYVC-ICPPNYTGE--LCDEVIDHCVPELNLCQHEAKCIP 1053
Query: 145 KSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
+ CE C GY +G C D D+C
Sbjct: 1054 LDKG--FSCE-CVPGY--SGKLCETDNDDC 1078
Score = 53.2 bits (122), Expect = 4e-06
Identities = 39/117 (33%), Positives = 46/117 (39%), Gaps = 12/117 (10%)
Query: 13 VTPFKLCVGE-RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRY 71
V LC E +C+ D+GF CE PG +T C A+ C G C D +G Y
Sbjct: 1039 VPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHG-AQCVDTING-Y 1096
Query: 72 QCGKCPSGFHGNGVE-------CYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG 121
C CP GF G E C C G C Q P C CP G+ G
Sbjct: 1097 TC-TCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTC-RCPPGFAG 1151
>AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein.
Length = 850
Score = 56.8 bits (131), Expect = 3e-07
Identities = 47/150 (31%), Positives = 57/150 (38%), Gaps = 17/150 (11%)
Query: 31 FRCERCPGSQTSDGQTCR-TACSANPC-FGGRVPCQDLPDGRYQCGKCPSGFHGNGVECY 88
+RC CP S T C NPC GG D + C CP GF G E
Sbjct: 366 YRCA-CPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCS-CPLGFEGQRCEIN 423
Query: 89 RISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP----CGRERRCMP 144
C N C +C + C CP Y G+ C V D P C E +C+P
Sbjct: 424 PDDCEDNDCENNATCVDGINNYVC-ICPPNYTGE--LCDEVIDHCVPELNLCQHEAKCIP 480
Query: 145 KSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
+ CE C GY +G C D D+C
Sbjct: 481 LDKG--FSCE-CVPGY--SGKLCETDNDDC 505
Score = 43.6 bits (98), Expect = 0.003
Identities = 27/71 (38%), Positives = 33/71 (46%), Gaps = 4/71 (5%)
Query: 13 VTPFKLCVGE-RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRY 71
V LC E +C+ D+GF CE PG +T C A+ C G C D +G Y
Sbjct: 466 VPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHG-AQCVDTING-Y 523
Query: 72 QCGKCPSGFHG 82
C CP GF G
Sbjct: 524 TC-TCPQGFSG 533
>AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein.
Length = 1523
Score = 56.8 bits (131), Expect = 3e-07
Identities = 47/150 (31%), Positives = 57/150 (38%), Gaps = 17/150 (11%)
Query: 31 FRCERCPGSQTSDGQTCR-TACSANPC-FGGRVPCQDLPDGRYQCGKCPSGFHGNGVECY 88
+RC CP S T C NPC GG D + C CP GF G E
Sbjct: 939 YRCA-CPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCS-CPLGFEGQRCEIN 996
Query: 89 RISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP----CGRERRCMP 144
C N C +C + C CP Y G+ C V D P C E +C+P
Sbjct: 997 PDDCEDNDCENNATCVDGINNYVC-ICPPNYTGE--LCDEVIDHCVPELNLCQHEAKCIP 1053
Query: 145 KSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
+ CE C GY +G C D D+C
Sbjct: 1054 LDKG--FSCE-CVPGY--SGKLCETDNDDC 1078
Score = 53.2 bits (122), Expect = 4e-06
Identities = 39/117 (33%), Positives = 46/117 (39%), Gaps = 12/117 (10%)
Query: 13 VTPFKLCVGE-RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRY 71
V LC E +C+ D+GF CE PG +T C A+ C G C D +G Y
Sbjct: 1039 VPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHG-AQCVDTING-Y 1096
Query: 72 QCGKCPSGFHGNGVE-------CYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG 121
C CP GF G E C C G C Q P C CP G+ G
Sbjct: 1097 TC-TCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTC-RCPPGFAG 1151
>AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein.
Length = 1559
Score = 56.8 bits (131), Expect = 3e-07
Identities = 47/150 (31%), Positives = 57/150 (38%), Gaps = 17/150 (11%)
Query: 31 FRCERCPGSQTSDGQTCR-TACSANPC-FGGRVPCQDLPDGRYQCGKCPSGFHGNGVECY 88
+RC CP S T C NPC GG D + C CP GF G E
Sbjct: 975 YRCA-CPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCS-CPLGFEGQRCEIN 1032
Query: 89 RISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP----CGRERRCMP 144
C N C +C + C CP Y G+ C V D P C E +C+P
Sbjct: 1033 PDDCEDNDCENNATCVDGINNYVC-ICPPNYTGE--LCDEVIDHCVPELNLCQHEAKCIP 1089
Query: 145 KSTSPYYECEGCPSGYQWNGYTC-VDMDEC 173
+ CE C GY +G C D D+C
Sbjct: 1090 LDKG--FSCE-CVPGY--SGKLCETDNDDC 1114
Score = 53.2 bits (122), Expect = 4e-06
Identities = 39/117 (33%), Positives = 46/117 (39%), Gaps = 12/117 (10%)
Query: 13 VTPFKLCVGE-RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRY 71
V LC E +C+ D+GF CE PG +T C A+ C G C D +G Y
Sbjct: 1075 VPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHG-AQCVDTING-Y 1132
Query: 72 QCGKCPSGFHGNGVE-------CYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVG 121
C CP GF G E C C G C Q P C CP G+ G
Sbjct: 1133 TC-TCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTC-RCPPGFAG 1187
>Z12172-1|CAA78163.1| 383|Homo sapiens putative homeotic protein
protein.
Length = 383
Score = 56.4 bits (130), Expect = 4e-07
Identities = 44/148 (29%), Positives = 54/148 (36%), Gaps = 8/148 (5%)
Query: 24 CVDTDQG-FRCERCPGSQTSDGQTCRTACSAN--PCFGGRVPCQDLPDGRYQCGKCPSGF 80
CV D G + C PG D Q C N PC G D + CP GF
Sbjct: 103 CVSLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGF 162
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
GN E SC N C C + +C CP G++ A PC
Sbjct: 163 SGNFCEIVANSCTPNPCENDGVCTDIGGDFRC-RCPAGFIDKTCSRPVTNCASSPCQNGG 221
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTCV 168
C+ + T YEC P ++ G TCV
Sbjct: 222 TCL-QHTQVSYECLCKP---EFTGLTCV 245
>U15979-1|AAA75364.1| 382|Homo sapiens dlk protein.
Length = 382
Score = 56.4 bits (130), Expect = 4e-07
Identities = 44/148 (29%), Positives = 54/148 (36%), Gaps = 8/148 (5%)
Query: 24 CVDTDQG-FRCERCPGSQTSDGQTCRTACSAN--PCFGGRVPCQDLPDGRYQCGKCPSGF 80
CV D G + C PG D Q C N PC G D + CP GF
Sbjct: 103 CVSLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGF 162
Query: 81 HGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRER 140
GN E SC N C C + +C CP G++ A PC
Sbjct: 163 SGNFCEIVANSCTPNPCENDGVCTDIGGDFRC-RCPAGFIDKTCSRPVTNCASSPCQNGG 221
Query: 141 RCMPKSTSPYYECEGCPSGYQWNGYTCV 168
C+ + T YEC P ++ G TCV
Sbjct: 222 TCL-QHTQVSYECLCKP---EFTGLTCV 245
>U57523-1|AAB06946.1| 446|Homo sapiens protein ( Human nel homolog
mRNA, partial cds. ).
Length = 446
Score = 56.0 bits (129), Expect = 5e-07
Identities = 53/196 (27%), Positives = 77/196 (39%), Gaps = 24/196 (12%)
Query: 50 ACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRA--NTCFQGVSCEET 106
A + C V C +LP G Y+C P + C C + + C + C T
Sbjct: 57 AAKMHYCHANTV-CVNLP-GLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNT 114
Query: 107 QYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYT 166
G C +C GYVG+G C+ C+ + C C+ + +C CPSG+ G
Sbjct: 115 VQGHSC-TCKPGYVGNGTICRAFCE--EGCRYGGTCVAPN-----KCV-CPSGF--TGSH 163
Query: 167 CV-DMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGN-ERRREHCVDVDE 224
C D+DEC + ++ C N S G+ G E C+D+DE
Sbjct: 164 CEKDIDECS-----EGIIECHNHSRCVNLPGWHHCECRS-GFHDDGTYSLSGESCIDIDE 217
Query: 225 CADGRANCPRGRLCVN 240
CA C C+N
Sbjct: 218 CALRTHTCWNDSACIN 233
Score = 41.1 bits (92), Expect = 0.015
Identities = 33/103 (32%), Positives = 42/103 (40%), Gaps = 24/103 (23%)
Query: 218 HCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPD 277
+C D+DECA C +CVN P G Y C G+ V+ C + D
Sbjct: 49 YCEDIDECAAKMHYCHANTVCVNLP-----------GLYRCDCVPGYIRVDDFS-CTEHD 96
Query: 278 ---SLVKRCDPSYCRRFNAVCGF---GQKCVCNTGWTGNGTVC 314
S CD NA+C G C C G+ GNGT+C
Sbjct: 97 ECGSGQHNCDE------NAICTNTVQGHSCTCKPGYVGNGTIC 133
>D83017-1|BAA11680.1| 810|Homo sapiens nel-related protein protein.
Length = 810
Score = 56.0 bits (129), Expect = 5e-07
Identities = 53/196 (27%), Positives = 77/196 (39%), Gaps = 24/196 (12%)
Query: 50 ACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRA--NTCFQGVSCEET 106
A + C V C +LP G Y+C P + C C + + C + C T
Sbjct: 439 AAKMHYCHANTV-CVNLP-GLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNT 496
Query: 107 QYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYT 166
G C +C GYVG+G C+ C+ + C C+ + +C CPSG+ G
Sbjct: 497 VQGHSC-TCKPGYVGNGTICRAFCE--EGCRYGGTCVAPN-----KCV-CPSGF--TGSH 545
Query: 167 CV-DMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGN-ERRREHCVDVDE 224
C D+DEC + ++ C N S G+ G E C+D+DE
Sbjct: 546 CEKDIDECS-----EGIIECHNHSRCVNLPGWYHCECRS-GFHDDGTYSLSGESCIDIDE 599
Query: 225 CADGRANCPRGRLCVN 240
CA C C+N
Sbjct: 600 CALRTHTCWNDSACIN 615
Score = 46.0 bits (104), Expect = 5e-04
Identities = 82/318 (25%), Positives = 113/318 (35%), Gaps = 64/318 (20%)
Query: 43 DGQTCRTA-CSANPCFGGRVPCQDL---PDGR--YQCGKC-----PSGFHGNGV--ECYR 89
DG CR C + R+ C L PD + G+C P +G V E R
Sbjct: 288 DGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQR 347
Query: 90 I---SCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKS 146
I SCR C GV + T+ P ++ QC VC C +C S
Sbjct: 348 ILTKSCRE--CRGGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENS 405
Query: 147 TSPYYE----CEGCPSGY---QWNGYTCVDMDECDL-IRPCDDLVSCRNEEXXXXXXXXX 198
+ CE C SGY Q + C D+DEC + C C N
Sbjct: 406 ECKNWNTKATCE-CKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVN-------LPGL 457
Query: 199 XXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYIC 258
G+ + EH DEC G+ NC +C NT Q
Sbjct: 458 YRCDCVPGYIRVDDFSCTEH----DECGSGQHNCDENAICTNTVQ--------------- 498
Query: 259 VPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDR 318
GH T +P + + + R R+ C KCVC +G+TG+ C ++
Sbjct: 499 ----GHSC--TCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSH--C--EK 548
Query: 319 DLDGHPDEQLPC-NEPRC 335
D+D + + C N RC
Sbjct: 549 DIDECSEGIIECHNHSRC 566
Score = 35.1 bits (77), Expect = 0.99
Identities = 67/294 (22%), Positives = 100/294 (34%), Gaps = 53/294 (18%)
Query: 86 ECYRISCRANTCFQGVSCEETQ----YGPKCG-SCPTGYV---GDGRQCQHV--CDAQKP 135
+C R+ N C +G C E + K C +GY+ GD C+ + C A+
Sbjct: 384 QCCRVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMH 443
Query: 136 -CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDE-------CDLIRPCDDLV---S 184
C C+ + Y C+ P + + ++C + DE CD C + V S
Sbjct: 444 YCHANTVCV--NLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHS 501
Query: 185 CRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCV------------DVDECADGRANC 232
C + +G R G CV D+DEC++G C
Sbjct: 502 CTCKPGYVGNGTICRAFC-EEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIEC 560
Query: 233 PRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHY----YVNTTRPCFDPDSLVKRCDPSYC 288
CVN P G Y C G + Y + C D D R +
Sbjct: 561 HNHSRCVNLP-----------GWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWN 609
Query: 289 RRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRCKKDNCPD 342
G C+C +G + +G C + L H + E RC +C D
Sbjct: 610 DSACINLAGGFDCLCPSGPSCSGD-CPHEGGLK-HNGQVWTLKEDRCSVCSCKD 661
>D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein
protein.
Length = 1095
Score = 56.0 bits (129), Expect = 5e-07
Identities = 39/112 (34%), Positives = 50/112 (44%), Gaps = 13/112 (11%)
Query: 71 YQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVC 130
Y C CP GF G+ + + C + C G +C G C C GY DG+ C
Sbjct: 6 YFC-HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLC-QCAPGY--DGQNCSKEL 61
Query: 131 DA--QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCV-DMDECDLIRPC 179
DA +PC C PK + C CP G+ G C D+DEC L +PC
Sbjct: 62 DACQSQPCHNHGTCTPKPGG--FHC-ACPPGFV--GLRCEGDVDEC-LDQPC 107
Score = 51.6 bits (118), Expect = 1e-05
Identities = 44/157 (28%), Positives = 65/157 (41%), Gaps = 13/157 (8%)
Query: 26 DTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGV 85
D+ + C PG Q S Q C + PC G C P G Y C +C G+ G
Sbjct: 1 DSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNG-ATCMAQPSG-YLC-QCAPGYDGQNC 57
Query: 86 ECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCM 143
+C++ C +C G C +CP G+V G +C+ D +PC
Sbjct: 58 SKELDACQSQPCHNHGTCTPKPGGFHC-ACPPGFV--GLRCEGDVDECLDQPCHPTGTAA 114
Query: 144 PKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPC 179
S + + C+ C G+ G C V++D C +PC
Sbjct: 115 CHSLANAFYCQ-CLPGH--TGQWCEVEIDPCH-SQPC 147
Score = 47.6 bits (108), Expect = 2e-04
Identities = 44/153 (28%), Positives = 57/153 (37%), Gaps = 16/153 (10%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCR---TACSANPCFGGRVPCQDLPDGRYQCGKCP 77
G C+ G+ C+ PG DGQ C AC + PC C P G + C CP
Sbjct: 34 GATCMAQPSGYLCQCAPG---YDGQNCSKELDACQSQPCH-NHGTCTPKPGG-FHCA-CP 87
Query: 78 SGFHGNGVECYRISCRANTCFQ--GVSCEETQYGPKCGSCPTGYVGDGRQCQ-HVCDAQK 134
GF G E C C +C C C G+ G + + C +Q
Sbjct: 88 PGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYC-QCLPGHTGQWCEVEIDPCHSQ- 145
Query: 135 PCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC 167
PC C + SP CP G++ G TC
Sbjct: 146 PCFHGGTCEATAGSPLGFICHCPKGFE--GPTC 176
Score = 44.8 bits (101), Expect = 0.001
Identities = 39/142 (27%), Positives = 49/142 (34%), Gaps = 9/142 (6%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFG-GRVPCQDLPDGRYQCGKCPSGFHG 82
C GF C PG + C PC G C L + Y C +C G G
Sbjct: 75 CTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFY-C-QCLPGHTG 132
Query: 83 NGVECYRISCRANTCFQGVSCEETQYGPK--CGSCPTGYVGDGRQCQHVCDA--QKPCGR 138
E C + CF G +CE T P CP G+ +G C H + C
Sbjct: 133 QWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGF--EGPTCSHRAPSCGFHHCHH 190
Query: 139 ERRCMPKSTSPYYECEGCPSGY 160
C+P + C SGY
Sbjct: 191 GGLCLPSPKPGFPPRCACLSGY 212
>DQ470680-1|ABF06672.1| 373|Homo sapiens CRELD2-zeta protein.
Length = 373
Score = 56.0 bits (129), Expect = 5e-07
Identities = 55/185 (29%), Positives = 66/185 (35%), Gaps = 30/185 (16%)
Query: 103 CEETQYGPKCGSCPTGYVGDGRQCQH-VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ 161
C GP C C GY R H +C A C + C S +C C G+
Sbjct: 168 CHMGYQGPLCTDCMDGYFSSLRNETHSICTA---C--DESCKTCSGLTNRDCGECEVGWV 222
Query: 162 WNGYTCVDMDECDLIRP-CDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERR----- 215
+ CVD+DEC P C C+N G G GN +
Sbjct: 223 LDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTG-EGPGNCKECISGY 281
Query: 216 -REH--CVDVDECADGRANCPR-GRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTR 271
REH C DVDEC+ C R C NTP GSY+CV G + T
Sbjct: 282 AREHGQCADVDECSLAEKTCVRKNENCYNTP-----------GSYVCVCPDG--FEETED 328
Query: 272 PCFDP 276
C P
Sbjct: 329 ACVPP 333
>DQ470678-1|ABF06670.1| 353|Homo sapiens CRELD2-delta protein.
Length = 353
Score = 56.0 bits (129), Expect = 5e-07
Identities = 55/185 (29%), Positives = 66/185 (35%), Gaps = 30/185 (16%)
Query: 103 CEETQYGPKCGSCPTGYVGDGRQCQH-VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ 161
C GP C C GY R H +C A C + C S +C C G+
Sbjct: 168 CHMGYQGPLCTDCMDGYFSSLRNETHSICTA---C--DESCKTCSGLTNRDCGECEVGWV 222
Query: 162 WNGYTCVDMDECDLIRP-CDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERR----- 215
+ CVD+DEC P C C+N G G GN +
Sbjct: 223 LDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTG-EGPGNCKECISGY 281
Query: 216 -REH--CVDVDECADGRANCPR-GRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTR 271
REH C DVDEC+ C R C NTP GSY+CV G + T
Sbjct: 282 AREHGQCADVDECSLAEKTCVRKNENCYNTP-----------GSYVCVCPDG--FEETED 328
Query: 272 PCFDP 276
C P
Sbjct: 329 ACVPP 333
>BC096102-1|AAH96102.1| 810|Homo sapiens NEL-like 1 (chicken)
protein.
Length = 810
Score = 56.0 bits (129), Expect = 5e-07
Identities = 53/196 (27%), Positives = 77/196 (39%), Gaps = 24/196 (12%)
Query: 50 ACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRA--NTCFQGVSCEET 106
A + C V C +LP G Y+C P + C C + + C + C T
Sbjct: 439 AAKMHYCHANTV-CVNLP-GLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNT 496
Query: 107 QYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYT 166
G C +C GYVG+G C+ C+ + C C+ + +C CPSG+ G
Sbjct: 497 VQGHSC-TCKPGYVGNGTICRAFCE--EGCRYGGTCVAPN-----KCV-CPSGF--TGSH 545
Query: 167 CV-DMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGN-ERRREHCVDVDE 224
C D+DEC + ++ C N S G+ G E C+D+DE
Sbjct: 546 CEKDIDECS-----EGIIECHNHSRCVNLPGWYHCECRS-GFHDDGTYSLSGESCIDIDE 599
Query: 225 CADGRANCPRGRLCVN 240
CA C C+N
Sbjct: 600 CALRTHTCWNDSACIN 615
Score = 46.0 bits (104), Expect = 5e-04
Identities = 82/318 (25%), Positives = 113/318 (35%), Gaps = 64/318 (20%)
Query: 43 DGQTCRTA-CSANPCFGGRVPCQDL---PDGR--YQCGKC-----PSGFHGNGV--ECYR 89
DG CR C + R+ C L PD + G+C P +G V E R
Sbjct: 288 DGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQR 347
Query: 90 I---SCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKS 146
I SCR C GV + T+ P ++ QC VC C +C S
Sbjct: 348 ILTKSCRE--CRGGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENS 405
Query: 147 TSPYYE----CEGCPSGY---QWNGYTCVDMDECDL-IRPCDDLVSCRNEEXXXXXXXXX 198
+ CE C SGY Q + C D+DEC + C C N
Sbjct: 406 ECKNWNTKATCE-CKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVN-------LPGL 457
Query: 199 XXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYIC 258
G+ + EH DEC G+ NC +C NT Q
Sbjct: 458 YRCDCVPGYIRVDDFSCTEH----DECGSGQHNCDENAICTNTVQ--------------- 498
Query: 259 VPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDR 318
GH T +P + + + R R+ C KCVC +G+TG+ C ++
Sbjct: 499 ----GHSC--TCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSH--C--EK 548
Query: 319 DLDGHPDEQLPC-NEPRC 335
D+D + + C N RC
Sbjct: 549 DIDECSEGIIECHNHSRC 566
Score = 35.1 bits (77), Expect = 0.99
Identities = 67/294 (22%), Positives = 100/294 (34%), Gaps = 53/294 (18%)
Query: 86 ECYRISCRANTCFQGVSCEETQ----YGPKCG-SCPTGYV---GDGRQCQHV--CDAQKP 135
+C R+ N C +G C E + K C +GY+ GD C+ + C A+
Sbjct: 384 QCCRVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMH 443
Query: 136 -CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDE-------CDLIRPCDDLV---S 184
C C+ + Y C+ P + + ++C + DE CD C + V S
Sbjct: 444 YCHANTVCV--NLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHS 501
Query: 185 CRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCV------------DVDECADGRANC 232
C + +G R G CV D+DEC++G C
Sbjct: 502 CTCKPGYVGNGTICRAFC-EEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIEC 560
Query: 233 PRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHY----YVNTTRPCFDPDSLVKRCDPSYC 288
CVN P G Y C G + Y + C D D R +
Sbjct: 561 HNHSRCVNLP-----------GWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWN 609
Query: 289 RRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRCKKDNCPD 342
G C+C +G + +G C + L H + E RC +C D
Sbjct: 610 DSACINLAGGFDCLCPSGPSCSGD-CPHEGGLK-HNGQVWTLKEDRCSVCSCKD 661
>BC096101-1|AAH96101.1| 810|Homo sapiens NEL-like 1 (chicken)
protein.
Length = 810
Score = 56.0 bits (129), Expect = 5e-07
Identities = 53/196 (27%), Positives = 77/196 (39%), Gaps = 24/196 (12%)
Query: 50 ACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRA--NTCFQGVSCEET 106
A + C V C +LP G Y+C P + C C + + C + C T
Sbjct: 439 AAKMHYCHANTV-CVNLP-GLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNT 496
Query: 107 QYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYT 166
G C +C GYVG+G C+ C+ + C C+ + +C CPSG+ G
Sbjct: 497 VQGHSC-TCKPGYVGNGTICRAFCE--EGCRYGGTCVAPN-----KCV-CPSGF--TGSH 545
Query: 167 CV-DMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGN-ERRREHCVDVDE 224
C D+DEC + ++ C N S G+ G E C+D+DE
Sbjct: 546 CEKDIDECS-----EGIIECHNHSRCVNLPGWYHCECRS-GFHDDGTYSLSGESCIDIDE 599
Query: 225 CADGRANCPRGRLCVN 240
CA C C+N
Sbjct: 600 CALRTHTCWNDSACIN 615
Score = 46.0 bits (104), Expect = 5e-04
Identities = 82/318 (25%), Positives = 113/318 (35%), Gaps = 64/318 (20%)
Query: 43 DGQTCRTA-CSANPCFGGRVPCQDL---PDGR--YQCGKC-----PSGFHGNGV--ECYR 89
DG CR C + R+ C L PD + G+C P +G V E R
Sbjct: 288 DGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQR 347
Query: 90 I---SCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKS 146
I SCR C GV + T+ P ++ QC VC C +C S
Sbjct: 348 ILTKSCRE--CRGGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENS 405
Query: 147 TSPYYE----CEGCPSGY---QWNGYTCVDMDECDL-IRPCDDLVSCRNEEXXXXXXXXX 198
+ CE C SGY Q + C D+DEC + C C N
Sbjct: 406 ECKNWNTKATCE-CKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVN-------LPGL 457
Query: 199 XXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYIC 258
G+ + EH DEC G+ NC +C NT Q
Sbjct: 458 YRCDCVPGYIRVDDFSCTEH----DECGSGQHNCDENAICTNTVQ--------------- 498
Query: 259 VPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDR 318
GH T +P + + + R R+ C KCVC +G+TG+ C ++
Sbjct: 499 ----GHSC--TCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSH--C--EK 548
Query: 319 DLDGHPDEQLPC-NEPRC 335
D+D + + C N RC
Sbjct: 549 DIDECSEGIIECHNHSRC 566
Score = 35.1 bits (77), Expect = 0.99
Identities = 67/294 (22%), Positives = 100/294 (34%), Gaps = 53/294 (18%)
Query: 86 ECYRISCRANTCFQGVSCEETQ----YGPKCG-SCPTGYV---GDGRQCQHV--CDAQKP 135
+C R+ N C +G C E + K C +GY+ GD C+ + C A+
Sbjct: 384 QCCRVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMH 443
Query: 136 -CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDE-------CDLIRPCDDLV---S 184
C C+ + Y C+ P + + ++C + DE CD C + V S
Sbjct: 444 YCHANTVCV--NLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHS 501
Query: 185 CRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCV------------DVDECADGRANC 232
C + +G R G CV D+DEC++G C
Sbjct: 502 CTCKPGYVGNGTICRAFC-EEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIEC 560
Query: 233 PRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHY----YVNTTRPCFDPDSLVKRCDPSYC 288
CVN P G Y C G + Y + C D D R +
Sbjct: 561 HNHSRCVNLP-----------GWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWN 609
Query: 289 RRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRCKKDNCPD 342
G C+C +G + +G C + L H + E RC +C D
Sbjct: 610 DSACINLAGGFDCLCPSGPSCSGD-CPHEGGLK-HNGQVWTLKEDRCSVCSCKD 661
>BC069674-1|AAH69674.1| 810|Homo sapiens nel-like 1, precursor
protein.
Length = 810
Score = 56.0 bits (129), Expect = 5e-07
Identities = 53/196 (27%), Positives = 77/196 (39%), Gaps = 24/196 (12%)
Query: 50 ACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRA--NTCFQGVSCEET 106
A + C V C +LP G Y+C P + C C + + C + C T
Sbjct: 439 AAKMHYCHANTV-CVNLP-GLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNT 496
Query: 107 QYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYT 166
G C +C GYVG+G C+ C+ + C C+ + +C CPSG+ G
Sbjct: 497 VQGHSC-TCKPGYVGNGTICRAFCE--EGCRYGGTCVAPN-----KCV-CPSGF--TGSH 545
Query: 167 CV-DMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGN-ERRREHCVDVDE 224
C D+DEC + ++ C N S G+ G E C+D+DE
Sbjct: 546 CEKDIDECS-----EGIIECHNHSRCVNLPGWYHCECRS-GFHDDGTYSLSGESCIDIDE 599
Query: 225 CADGRANCPRGRLCVN 240
CA C C+N
Sbjct: 600 CALRTHTCWNDSACIN 615
Score = 46.0 bits (104), Expect = 5e-04
Identities = 82/318 (25%), Positives = 113/318 (35%), Gaps = 64/318 (20%)
Query: 43 DGQTCRTA-CSANPCFGGRVPCQDL---PDGR--YQCGKC-----PSGFHGNGV--ECYR 89
DG CR C + R+ C L PD + G+C P +G V E R
Sbjct: 288 DGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQR 347
Query: 90 I---SCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKS 146
I SCR C GV + T+ P ++ QC VC C +C S
Sbjct: 348 ILTKSCRE--CRGGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENS 405
Query: 147 TSPYYE----CEGCPSGY---QWNGYTCVDMDECDL-IRPCDDLVSCRNEEXXXXXXXXX 198
+ CE C SGY Q + C D+DEC + C C N
Sbjct: 406 ECKNWNTKATCE-CKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVN-------LPGL 457
Query: 199 XXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYIC 258
G+ + EH DEC G+ NC +C NT Q
Sbjct: 458 YRCDCVPGYIRVDDFSCTEH----DECGSGQHNCDENAICTNTVQ--------------- 498
Query: 259 VPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVCGLDR 318
GH T +P + + + R R+ C KCVC +G+TG+ C ++
Sbjct: 499 ----GHSC--TCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSH--C--EK 548
Query: 319 DLDGHPDEQLPC-NEPRC 335
D+D + + C N RC
Sbjct: 549 DIDECSEGIIECHNHSRC 566
Score = 35.1 bits (77), Expect = 0.99
Identities = 67/294 (22%), Positives = 100/294 (34%), Gaps = 53/294 (18%)
Query: 86 ECYRISCRANTCFQGVSCEETQ----YGPKCG-SCPTGYV---GDGRQCQHV--CDAQKP 135
+C R+ N C +G C E + K C +GY+ GD C+ + C A+
Sbjct: 384 QCCRVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMH 443
Query: 136 -CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDE-------CDLIRPCDDLV---S 184
C C+ + Y C+ P + + ++C + DE CD C + V S
Sbjct: 444 YCHANTVCV--NLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHS 501
Query: 185 CRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCV------------DVDECADGRANC 232
C + +G R G CV D+DEC++G C
Sbjct: 502 CTCKPGYVGNGTICRAFC-EEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIEC 560
Query: 233 PRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHY----YVNTTRPCFDPDSLVKRCDPSYC 288
CVN P G Y C G + Y + C D D R +
Sbjct: 561 HNHSRCVNLP-----------GWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWN 609
Query: 289 RRFNAVCGFGQKCVCNTGWTGNGTVCGLDRDLDGHPDEQLPCNEPRCKKDNCPD 342
G C+C +G + +G C + L H + E RC +C D
Sbjct: 610 DSACINLAGGFDCLCPSGPSCSGD-CPHEGGLK-HNGQVWTLKEDRCSVCSCKD 661
>AY358355-1|AAQ88721.1| 353|Homo sapiens RLPR185 protein.
Length = 353
Score = 56.0 bits (129), Expect = 5e-07
Identities = 55/185 (29%), Positives = 66/185 (35%), Gaps = 30/185 (16%)
Query: 103 CEETQYGPKCGSCPTGYVGDGRQCQH-VCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQ 161
C GP C C GY R H +C A C + C S +C C G+
Sbjct: 168 CHMGYQGPLCTDCMDGYFSSLRNETHSICTA---C--DESCKTCSGLTNRDCGECEVGWV 222
Query: 162 WNGYTCVDMDECDLIRP-CDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERR----- 215
+ CVD+DEC P C C+N G G GN +
Sbjct: 223 LDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTG-EGPGNCKECISGY 281
Query: 216 -REH--CVDVDECADGRANCPR-GRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTR 271
REH C DVDEC+ C R C NTP GSY+CV G + T
Sbjct: 282 AREHGQCADVDECSLAEKTCVRKNENCYNTP-----------GSYVCVCPDG--FEETED 328
Query: 272 PCFDP 276
C P
Sbjct: 329 ACVPP 333
>X87241-1|CAA60685.1| 4590|Homo sapiens homologue of Drosophila Fat
protein protein.
Length = 4590
Score = 55.6 bits (128), Expect = 7e-07
Identities = 44/143 (30%), Positives = 56/143 (39%), Gaps = 11/143 (7%)
Query: 46 TCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEE 105
T C++NPC G V C P G Y C KC + + G E C +N C G +C
Sbjct: 4014 TATEDCASNPCQNGGV-CNPSPAGGYYC-KCSALYIGTHCEISVNPCSSNPCLYGGTCVV 4071
Query: 106 TQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGY 165
G C C Y G Q C +PC C +C+ SG++ G
Sbjct: 4072 DNGGFVC-QCRGLYTGQRCQLSPYC-KDEPCKNGGTCFDSLDGAVCQCD---SGFR--GE 4124
Query: 166 TC-VDMDECDLIRPCDDLVSCRN 187
C D+DEC PC C N
Sbjct: 4125 RCQSDIDECS-GNPCLHGALCEN 4146
Score = 53.2 bits (122), Expect = 4e-06
Identities = 40/115 (34%), Positives = 48/115 (41%), Gaps = 11/115 (9%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGKCPS 78
G CV + GF C+ C G T GQ C+ + C PC G C D DG C +C S
Sbjct: 4066 GGTCVVDNGGFVCQ-CRGLYT--GQRCQLSPYCKDEPCKNGGT-CFDSLDGAV-C-QCDS 4119
Query: 79 GFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQ 133
GF G + C N C G CE T C +C Y GR C+ Q
Sbjct: 4120 GFRGERCQSDIDECSGNPCLHGALCENTHGSYHC-NCSHEY--RGRHCEDAAPNQ 4171
Score = 32.3 bits (70), Expect = 7.0
Identities = 44/180 (24%), Positives = 61/180 (33%), Gaps = 25/180 (13%)
Query: 92 CRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYY 151
C +N C G C + G C Y+G + + PC C+ +
Sbjct: 4019 CASNPCQNGGVCNPSPAGGYYCKCSALYIGTHCEISVNPCSSNPCLYGGTCVVDNGGFVC 4078
Query: 152 ECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTG 211
+C G +G C L C D C+N S G+RG
Sbjct: 4079 QCRGLYTG-----------QRCQLSPYCKD-EPCKNGGTCFDSLDGAVCQCDS-GFRG-- 4123
Query: 212 NERRREHC-VDVDECADGRANCPRGRLCVNT-PQYPSNPVSSLQGSYICVPCGGHYYVNT 269
E C D+DEC+ C G LC NT Y N +G + C + YV+T
Sbjct: 4124 -----ERCQSDIDECSGN--PCLHGALCENTHGSYHCNCSHEYRGRH-CEDAAPNQYVST 4175
>X62008-1|CAB56534.1| 517|Homo sapiens fibrillin 15 protein.
Length = 517
Score = 55.6 bits (128), Expect = 7e-07
Identities = 79/311 (25%), Positives = 116/311 (37%), Gaps = 54/311 (17%)
Query: 18 LCVGERCVDTDQGFRCERCPGSQTSDGQ----TCRTACSANPCFGGRVPCQDLPDGRYQC 73
LC +C +T F+C RC D + T C +P GR C + P G ++C
Sbjct: 242 LCTHGKCRNTIGSFKC-RCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTP-GDFEC 299
Query: 74 GKCPSGFHGNGV---ECYRIS-CRANTCF-QGVSCEETQYGPKCGSCPTGYVGDGR--QC 126
KC G+ + C I C+ + +G C T+ +C CP G+ C
Sbjct: 300 -KCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRC-ECPPGHQLSPNISAC 357
Query: 127 QHV--CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIR-PCDD 181
+ C+ RC+ + Y+C C GY + CVD+DEC ++ C+
Sbjct: 358 IDINECELSAHLCPNGRCV--NLIGKYQC-ACNPGYHSTPDRLFCVDIDECSIMNGGCET 414
Query: 182 LVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNT 241
C N E G+ ++R C D+DEC D C G+ C N
Sbjct: 415 F--CTNSE-------GSYECSCQPGFALMPDQR---SCTDIDECEDNPNICDGGQ-CTNI 461
Query: 242 PQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCD--PSYCRRFNAVCGFGQ 299
P G Y C+ G + C D V CD P+ C G
Sbjct: 462 P-----------GEYRCLCYDGFMASEDMKTCVD----VNECDLNPNICLSGTCENTKGS 506
Query: 300 -KCVCNTGWTG 309
C C+ G++G
Sbjct: 507 FICHCDMGYSG 517
>U03877-1|AAA65590.1| 387|Homo sapiens extracellular protein
protein.
Length = 387
Score = 55.2 bits (127), Expect = 9e-07
Identities = 65/227 (28%), Positives = 86/227 (37%), Gaps = 39/227 (17%)
Query: 54 NPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRANT--CFQGVSCEETQYGP 110
NP R+P P R QC N C I C A T C C +
Sbjct: 36 NPADPQRIPSN--PSHRIQCAAGYEQSEHN--VCQDIDECTAGTHNCRADQVCINLRGSF 91
Query: 111 KCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCV 168
C CP GY G QC + + P +RC+ +T + C+ C G+Q N YTCV
Sbjct: 92 AC-QCPPGYQKRGEQCVDIDECTIPPYCHQRCV--NTPGSFYCQ-CSPGFQLAANNYTCV 147
Query: 169 DMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADG 228
D++ECD C C N +QG+ + + R +C D+DEC
Sbjct: 148 DINECDASNQCAQ--QCYN-------ILGSFICQCNQGYELSSD---RLNCEDIDECRTS 195
Query: 229 RANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFD 275
C CVN P G + C+ C Y V +R C D
Sbjct: 196 SYLCQ--YQCVNEP-----------GKFSCM-CPQGYQVVRSRTCQD 228
Score = 41.1 bits (92), Expect = 0.015
Identities = 47/174 (27%), Positives = 69/174 (39%), Gaps = 21/174 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
C++ F C+ CP G+ C C+ P R C + P G + C +C GF
Sbjct: 84 CINLRGSFACQ-CPPGYQKRGEQCVDIDECTIPPYCHQR--CVNTP-GSFYC-QCSPGFQ 138
Query: 82 --GNGVECYRIS-CRA-NTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQCQHVCDAQKP 135
N C I+ C A N C Q C C C GY D C+ + + +
Sbjct: 139 LAANNYTCVDINECDASNQCAQ--QCYNILGSFIC-QCNQGYELSSDRLNCEDIDECRTS 195
Query: 136 CGR-ERRCMPKSTSPYYECEGCPSGYQW-NGYTCVDMDECDLIRPCDDLVSCRN 187
+ +C+ + + C CP GYQ TC D++EC+ C + C N
Sbjct: 196 SYLCQYQCVNEPGK--FSCM-CPQGYQVVRSRTCQDINECETTNECREDEMCWN 246
Score = 39.1 bits (87), Expect = 0.061
Identities = 35/130 (26%), Positives = 51/130 (39%), Gaps = 14/130 (10%)
Query: 22 ERCVDTDQGFRCERCPGSQ-TSDGQTCRTACSANPCFGGRVPCQDLPD--GRYQCGKCPS 78
+RCV+T F C+ PG Q ++ TC N C Q + G + C +C
Sbjct: 120 QRCVNTPGSFYCQCSPGFQLAANNYTC---VDINECDASNQCAQQCYNILGSFIC-QCNQ 175
Query: 79 GFH--GNGVECYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGY-VGDGRQCQHV--CDA 132
G+ + + C I CR ++ C C CP GY V R CQ + C+
Sbjct: 176 GYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSC-MCPQGYQVVRSRTCQDINECET 234
Query: 133 QKPCGRERRC 142
C + C
Sbjct: 235 TNECREDEMC 244
Score = 32.7 bits (71), Expect = 5.3
Identities = 26/90 (28%), Positives = 35/90 (38%), Gaps = 18/90 (20%)
Query: 219 CVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYIC-VPCGGHYYVNTTRPCFDPD 277
C D+DEC G NC ++C+N L+GS+ C P G Y C D D
Sbjct: 65 CQDIDECTAGTHNCRADQVCIN-----------LRGSFACQCPPG---YQKRGEQCVDID 110
Query: 278 SLVKRCDPSYCRRFNAVCGFGQKCVCNTGW 307
P YC + C C+ G+
Sbjct: 111 ECT---IPPYCHQRCVNTPGSFYCQCSPGF 137
Score = 32.3 bits (70), Expect = 7.0
Identities = 31/100 (31%), Positives = 41/100 (41%), Gaps = 23/100 (23%)
Query: 211 GNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTT 270
G ++R E CVD+DEC C + CVNTP GS+ C G
Sbjct: 98 GYQKRGEQCVDIDECTI-PPYC--HQRCVNTP-----------GSFYCQCSPGFQLAANN 143
Query: 271 RPCFDPDSLVKRCDPS-YCRR--FNAVCGFGQKCVCNTGW 307
C D + CD S C + +N + F C CN G+
Sbjct: 144 YTCVD----INECDASNQCAQQCYNILGSF--ICQCNQGY 177
>BC098561-1|AAH98561.1| 493|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 protein.
Length = 493
Score = 55.2 bits (127), Expect = 9e-07
Identities = 65/227 (28%), Positives = 86/227 (37%), Gaps = 39/227 (17%)
Query: 54 NPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRANT--CFQGVSCEETQYGP 110
NP R+P P R QC N C I C A T C C +
Sbjct: 142 NPADPQRIPSN--PSHRIQCAAGYEQSEHN--VCQDIDECTAGTHNCRADQVCINLRGSF 197
Query: 111 KCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCV 168
C CP GY G QC + + P +RC+ +T + C+ C G+Q N YTCV
Sbjct: 198 AC-QCPPGYQKRGEQCVDIDECTIPPYCHQRCV--NTPGSFYCQ-CSPGFQLAANNYTCV 253
Query: 169 DMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADG 228
D++ECD C C N +QG+ + + R +C D+DEC
Sbjct: 254 DINECDASNQCAQ--QCYN-------ILGSFICQCNQGYELSSD---RLNCEDIDECRTS 301
Query: 229 RANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFD 275
C CVN P G + C+ C Y V +R C D
Sbjct: 302 SYLCQ--YQCVNEP-----------GKFSCM-CPQGYQVVRSRTCQD 334
Score = 41.1 bits (92), Expect = 0.015
Identities = 47/174 (27%), Positives = 69/174 (39%), Gaps = 21/174 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
C++ F C+ CP G+ C C+ P R C + P G + C +C GF
Sbjct: 190 CINLRGSFACQ-CPPGYQKRGEQCVDIDECTIPPYCHQR--CVNTP-GSFYC-QCSPGFQ 244
Query: 82 --GNGVECYRIS-CRA-NTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQCQHVCDAQKP 135
N C I+ C A N C Q C C C GY D C+ + + +
Sbjct: 245 LAANNYTCVDINECDASNQCAQ--QCYNILGSFIC-QCNQGYELSSDRLNCEDIDECRTS 301
Query: 136 CGR-ERRCMPKSTSPYYECEGCPSGYQW-NGYTCVDMDECDLIRPCDDLVSCRN 187
+ +C+ + + C CP GYQ TC D++EC+ C + C N
Sbjct: 302 SYLCQYQCVNEPGK--FSCM-CPQGYQVVRSRTCQDINECETTNECREDEMCWN 352
Score = 39.1 bits (87), Expect = 0.061
Identities = 35/130 (26%), Positives = 51/130 (39%), Gaps = 14/130 (10%)
Query: 22 ERCVDTDQGFRCERCPGSQ-TSDGQTCRTACSANPCFGGRVPCQDLPD--GRYQCGKCPS 78
+RCV+T F C+ PG Q ++ TC N C Q + G + C +C
Sbjct: 226 QRCVNTPGSFYCQCSPGFQLAANNYTC---VDINECDASNQCAQQCYNILGSFIC-QCNQ 281
Query: 79 GFH--GNGVECYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGY-VGDGRQCQHV--CDA 132
G+ + + C I CR ++ C C CP GY V R CQ + C+
Sbjct: 282 GYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSC-MCPQGYQVVRSRTCQDINECET 340
Query: 133 QKPCGRERRC 142
C + C
Sbjct: 341 TNECREDEMC 350
Score = 32.7 bits (71), Expect = 5.3
Identities = 26/90 (28%), Positives = 35/90 (38%), Gaps = 18/90 (20%)
Query: 219 CVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYIC-VPCGGHYYVNTTRPCFDPD 277
C D+DEC G NC ++C+N L+GS+ C P G Y C D D
Sbjct: 171 CQDIDECTAGTHNCRADQVCIN-----------LRGSFACQCPPG---YQKRGEQCVDID 216
Query: 278 SLVKRCDPSYCRRFNAVCGFGQKCVCNTGW 307
P YC + C C+ G+
Sbjct: 217 ECT---IPPYCHQRCVNTPGSFYCQCSPGF 243
Score = 32.3 bits (70), Expect = 7.0
Identities = 31/100 (31%), Positives = 41/100 (41%), Gaps = 23/100 (23%)
Query: 211 GNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTT 270
G ++R E CVD+DEC C + CVNTP GS+ C G
Sbjct: 204 GYQKRGEQCVDIDECTI-PPYC--HQRCVNTP-----------GSFYCQCSPGFQLAANN 249
Query: 271 RPCFDPDSLVKRCDPS-YCRR--FNAVCGFGQKCVCNTGW 307
C D + CD S C + +N + F C CN G+
Sbjct: 250 YTCVD----INECDASNQCAQQCYNILGSF--ICQCNQGY 283
>BC014410-1|AAH14410.1| 493|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 protein.
Length = 493
Score = 55.2 bits (127), Expect = 9e-07
Identities = 65/227 (28%), Positives = 86/227 (37%), Gaps = 39/227 (17%)
Query: 54 NPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRANT--CFQGVSCEETQYGP 110
NP R+P P R QC N C I C A T C C +
Sbjct: 142 NPADPQRIPSN--PSHRIQCAAGYEQSEHN--VCQDIDECTAGTHNCRADQVCINLRGSF 197
Query: 111 KCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCV 168
C CP GY G QC + + P +RC+ +T + C+ C G+Q N YTCV
Sbjct: 198 AC-QCPPGYQKRGEQCVDIDECTIPPYCHQRCV--NTPGSFYCQ-CSPGFQLAANNYTCV 253
Query: 169 DMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADG 228
D++ECD C C N +QG+ + + R +C D+DEC
Sbjct: 254 DINECDASNQCAQ--QCYN-------ILGSFICQCNQGYELSSD---RLNCEDIDECRTS 301
Query: 229 RANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFD 275
C CVN P G + C+ C Y V +R C D
Sbjct: 302 SYLCQ--YQCVNEP-----------GKFSCM-CPQGYQVVRSRTCQD 334
Score = 41.1 bits (92), Expect = 0.015
Identities = 47/174 (27%), Positives = 69/174 (39%), Gaps = 21/174 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
C++ F C+ CP G+ C C+ P R C + P G + C +C GF
Sbjct: 190 CINLRGSFACQ-CPPGYQKRGEQCVDIDECTIPPYCHQR--CVNTP-GSFYC-QCSPGFQ 244
Query: 82 --GNGVECYRIS-CRA-NTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQCQHVCDAQKP 135
N C I+ C A N C Q C C C GY D C+ + + +
Sbjct: 245 LAANNYTCVDINECDASNQCAQ--QCYNILGSFIC-QCNQGYELSSDRLNCEDIDECRTS 301
Query: 136 CGR-ERRCMPKSTSPYYECEGCPSGYQW-NGYTCVDMDECDLIRPCDDLVSCRN 187
+ +C+ + + C CP GYQ TC D++EC+ C + C N
Sbjct: 302 SYLCQYQCVNEPGK--FSCM-CPQGYQVVRSRTCQDINECETTNECREDEMCWN 352
Score = 39.1 bits (87), Expect = 0.061
Identities = 35/130 (26%), Positives = 51/130 (39%), Gaps = 14/130 (10%)
Query: 22 ERCVDTDQGFRCERCPGSQ-TSDGQTCRTACSANPCFGGRVPCQDLPD--GRYQCGKCPS 78
+RCV+T F C+ PG Q ++ TC N C Q + G + C +C
Sbjct: 226 QRCVNTPGSFYCQCSPGFQLAANNYTC---VDINECDASNQCAQQCYNILGSFIC-QCNQ 281
Query: 79 GFH--GNGVECYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGY-VGDGRQCQHV--CDA 132
G+ + + C I CR ++ C C CP GY V R CQ + C+
Sbjct: 282 GYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSC-MCPQGYQVVRSRTCQDINECET 340
Query: 133 QKPCGRERRC 142
C + C
Sbjct: 341 TNECREDEMC 350
Score = 32.7 bits (71), Expect = 5.3
Identities = 26/90 (28%), Positives = 35/90 (38%), Gaps = 18/90 (20%)
Query: 219 CVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYIC-VPCGGHYYVNTTRPCFDPD 277
C D+DEC G NC ++C+N L+GS+ C P G Y C D D
Sbjct: 171 CQDIDECTAGTHNCRADQVCIN-----------LRGSFACQCPPG---YQKRGEQCVDID 216
Query: 278 SLVKRCDPSYCRRFNAVCGFGQKCVCNTGW 307
P YC + C C+ G+
Sbjct: 217 ECT---IPPYCHQRCVNTPGSFYCQCSPGF 243
Score = 32.3 bits (70), Expect = 7.0
Identities = 31/100 (31%), Positives = 41/100 (41%), Gaps = 23/100 (23%)
Query: 211 GNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTT 270
G ++R E CVD+DEC C + CVNTP GS+ C G
Sbjct: 204 GYQKRGEQCVDIDECTI-PPYC--HQRCVNTP-----------GSFYCQCSPGFQLAANN 249
Query: 271 RPCFDPDSLVKRCDPS-YCRR--FNAVCGFGQKCVCNTGW 307
C D + CD S C + +N + F C CN G+
Sbjct: 250 YTCVD----INECDASNQCAQQCYNILGSF--ICQCNQGY 283
>AY004330-1|AAK11491.1| 493|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 protein.
Length = 493
Score = 55.2 bits (127), Expect = 9e-07
Identities = 65/227 (28%), Positives = 86/227 (37%), Gaps = 39/227 (17%)
Query: 54 NPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRANT--CFQGVSCEETQYGP 110
NP R+P P R QC N C I C A T C C +
Sbjct: 142 NPADPQRIPSN--PSHRIQCAAGYEQSEHN--VCQDIDECTAGTHNCRADQVCINLRGSF 197
Query: 111 KCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCV 168
C CP GY G QC + + P +RC+ +T + C+ C G+Q N YTCV
Sbjct: 198 AC-QCPPGYQKRGEQCVDIDECTIPPYCHQRCV--NTPGSFYCQ-CSPGFQLAANNYTCV 253
Query: 169 DMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADG 228
D++ECD C C N +QG+ + + R +C D+DEC
Sbjct: 254 DINECDASNQCAQ--QCYN-------ILGSFICQCNQGYELSSD---RLNCEDIDECRTS 301
Query: 229 RANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFD 275
C CVN P G + C+ C Y V +R C D
Sbjct: 302 SYLCQ--YQCVNEP-----------GKFSCM-CPQGYQVVRSRTCQD 334
Score = 41.1 bits (92), Expect = 0.015
Identities = 47/174 (27%), Positives = 69/174 (39%), Gaps = 21/174 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
C++ F C+ CP G+ C C+ P R C + P G + C +C GF
Sbjct: 190 CINLRGSFACQ-CPPGYQKRGEQCVDIDECTIPPYCHQR--CVNTP-GSFYC-QCSPGFQ 244
Query: 82 --GNGVECYRIS-CRA-NTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQCQHVCDAQKP 135
N C I+ C A N C Q C C C GY D C+ + + +
Sbjct: 245 LAANNYTCVDINECDASNQCAQ--QCYNILGSFIC-QCNQGYELSSDRLNCEDIDECRTS 301
Query: 136 CGR-ERRCMPKSTSPYYECEGCPSGYQW-NGYTCVDMDECDLIRPCDDLVSCRN 187
+ +C+ + + C CP GYQ TC D++EC+ C + C N
Sbjct: 302 SYLCQYQCVNEPGK--FSCM-CPQGYQVVRSRTCQDINECETTNECREDEMCWN 352
Score = 39.1 bits (87), Expect = 0.061
Identities = 35/130 (26%), Positives = 51/130 (39%), Gaps = 14/130 (10%)
Query: 22 ERCVDTDQGFRCERCPGSQ-TSDGQTCRTACSANPCFGGRVPCQDLPD--GRYQCGKCPS 78
+RCV+T F C+ PG Q ++ TC N C Q + G + C +C
Sbjct: 226 QRCVNTPGSFYCQCSPGFQLAANNYTC---VDINECDASNQCAQQCYNILGSFIC-QCNQ 281
Query: 79 GFH--GNGVECYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGY-VGDGRQCQHV--CDA 132
G+ + + C I CR ++ C C CP GY V R CQ + C+
Sbjct: 282 GYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSC-MCPQGYQVVRSRTCQDINECET 340
Query: 133 QKPCGRERRC 142
C + C
Sbjct: 341 TNECREDEMC 350
Score = 32.7 bits (71), Expect = 5.3
Identities = 26/90 (28%), Positives = 35/90 (38%), Gaps = 18/90 (20%)
Query: 219 CVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYIC-VPCGGHYYVNTTRPCFDPD 277
C D+DEC G NC ++C+N L+GS+ C P G Y C D D
Sbjct: 171 CQDIDECTAGTHNCRADQVCIN-----------LRGSFACQCPPG---YQKRGEQCVDID 216
Query: 278 SLVKRCDPSYCRRFNAVCGFGQKCVCNTGW 307
P YC + C C+ G+
Sbjct: 217 ECT---IPPYCHQRCVNTPGSFYCQCSPGF 243
Score = 32.3 bits (70), Expect = 7.0
Identities = 31/100 (31%), Positives = 41/100 (41%), Gaps = 23/100 (23%)
Query: 211 GNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTT 270
G ++R E CVD+DEC C + CVNTP GS+ C G
Sbjct: 204 GYQKRGEQCVDIDECTI-PPYC--HQRCVNTP-----------GSFYCQCSPGFQLAANN 249
Query: 271 RPCFDPDSLVKRCDPS-YCRR--FNAVCGFGQKCVCNTGW 307
C D + CD S C + +N + F C CN G+
Sbjct: 250 YTCVD----INECDASNQCAQQCYNILGSF--ICQCNQGY 283
>AB209212-1|BAD92449.1| 418|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 isoform b
variant protein.
Length = 418
Score = 55.2 bits (127), Expect = 9e-07
Identities = 65/227 (28%), Positives = 86/227 (37%), Gaps = 39/227 (17%)
Query: 54 NPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRIS-CRANT--CFQGVSCEETQYGP 110
NP R+P P R QC N C I C A T C C +
Sbjct: 67 NPADPQRIPSN--PSHRIQCAAGYEQSEHN--VCQDIDECTAGTHNCRADQVCINLRGSF 122
Query: 111 KCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMPKSTSPYYECEGCPSGYQW--NGYTCV 168
C CP GY G QC + + P +RC+ +T + C+ C G+Q N YTCV
Sbjct: 123 AC-QCPPGYQKRGEQCVDIDECTIPPYCHQRCV--NTPGSFYCQ-CSPGFQLAANNYTCV 178
Query: 169 DMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADG 228
D++ECD C C N +QG+ + + R +C D+DEC
Sbjct: 179 DINECDASNQCAQ--QCYN-------ILGSFICQCNQGYELSSD---RLNCEDIDECRTS 226
Query: 229 RANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTTRPCFD 275
C CVN P G + C+ C Y V +R C D
Sbjct: 227 SYLCQ--YQCVNQP-----------GKFSCM-CPQGYQVVRSRTCQD 259
Score = 41.1 bits (92), Expect = 0.015
Identities = 47/174 (27%), Positives = 69/174 (39%), Gaps = 21/174 (12%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA--CSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
C++ F C+ CP G+ C C+ P R C + P G + C +C GF
Sbjct: 115 CINLRGSFACQ-CPPGYQKRGEQCVDIDECTIPPYCHQR--CVNTP-GSFYC-QCSPGFQ 169
Query: 82 --GNGVECYRIS-CRA-NTCFQGVSCEETQYGPKCGSCPTGYV--GDGRQCQHVCDAQKP 135
N C I+ C A N C Q C C C GY D C+ + + +
Sbjct: 170 LAANNYTCVDINECDASNQCAQ--QCYNILGSFIC-QCNQGYELSSDRLNCEDIDECRTS 226
Query: 136 CGR-ERRCMPKSTSPYYECEGCPSGYQW-NGYTCVDMDECDLIRPCDDLVSCRN 187
+ +C+ + + C CP GYQ TC D++EC+ C + C N
Sbjct: 227 SYLCQYQCVNQPGK--FSCM-CPQGYQVVRSRTCQDINECETTNECREDEMCWN 277
Score = 39.9 bits (89), Expect = 0.035
Identities = 36/130 (27%), Positives = 52/130 (40%), Gaps = 14/130 (10%)
Query: 22 ERCVDTDQGFRCERCPGSQ-TSDGQTCRTACSANPCFGGRVPCQDLPD--GRYQCGKCPS 78
+RCV+T F C+ PG Q ++ TC N C Q + G + C +C
Sbjct: 151 QRCVNTPGSFYCQCSPGFQLAANNYTC---VDINECDASNQCAQQCYNILGSFIC-QCNQ 206
Query: 79 GFH--GNGVECYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGY-VGDGRQCQHV--CDA 132
G+ + + C I CR ++ C Q G CP GY V R CQ + C+
Sbjct: 207 GYELSSDRLNCEDIDECRTSSYLCQYQC-VNQPGKFSCMCPQGYQVVRSRTCQDINECET 265
Query: 133 QKPCGRERRC 142
C + C
Sbjct: 266 TNECREDEMC 275
Score = 32.7 bits (71), Expect = 5.3
Identities = 26/90 (28%), Positives = 35/90 (38%), Gaps = 18/90 (20%)
Query: 219 CVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYIC-VPCGGHYYVNTTRPCFDPD 277
C D+DEC G NC ++C+N L+GS+ C P G Y C D D
Sbjct: 96 CQDIDECTAGTHNCRADQVCIN-----------LRGSFACQCPPG---YQKRGEQCVDID 141
Query: 278 SLVKRCDPSYCRRFNAVCGFGQKCVCNTGW 307
P YC + C C+ G+
Sbjct: 142 ECT---IPPYCHQRCVNTPGSFYCQCSPGF 168
Score = 32.3 bits (70), Expect = 7.0
Identities = 31/100 (31%), Positives = 41/100 (41%), Gaps = 23/100 (23%)
Query: 211 GNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGGHYYVNTT 270
G ++R E CVD+DEC C + CVNTP GS+ C G
Sbjct: 129 GYQKRGEQCVDIDECTI-PPYC--HQRCVNTP-----------GSFYCQCSPGFQLAANN 174
Query: 271 RPCFDPDSLVKRCDPS-YCRR--FNAVCGFGQKCVCNTGW 307
C D + CD S C + +N + F C CN G+
Sbjct: 175 YTCVD----INECDASNQCAQQCYNILGSF--ICQCNQGY 208
>D86425-1|BAA13087.1| 1376|Homo sapiens osteonidogen protein.
Length = 1376
Score = 54.8 bits (126), Expect = 1e-06
Identities = 42/147 (28%), Positives = 58/147 (39%), Gaps = 15/147 (10%)
Query: 8 DAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQ-TCRTACS-ANPCFGGRVPCQ 64
D T F C C++ +RCE G + +D + TC ANPC G C
Sbjct: 802 DENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCA 861
Query: 65 DLPDGR--------YQCGKCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSC 115
R + C C G+ G+G +C + C N C +C T C C
Sbjct: 862 PAGQARCVHHGGSTFSCA-CLPGYAGDGHQCTDVDECSENRCHPAATCYNTPGSFSC-RC 919
Query: 116 PTGYVGDGRQC-QHVCDAQKPCGRERR 141
GY GDG QC + PC +++R
Sbjct: 920 QPGYYGDGFQCIPDSTSSLTPCEQQQR 946
Score = 48.0 bits (109), Expect = 1e-04
Identities = 47/163 (28%), Positives = 68/163 (41%), Gaps = 27/163 (16%)
Query: 95 NTCFQGVS-CEET-QYGPKCG-----SCPTGYVGDGRQC--QHVCDAQ-KPCGRERRCMP 144
N C+ G C+ T + P G C +GY GDGR C ++ C CG C+
Sbjct: 762 NPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCIN 821
Query: 145 KSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDD---LVSCRNEEXXXXXXXXXX 199
S Y CE C SGY++ + +TC+ + PC+D + +
Sbjct: 822 LPGS--YRCE-CRSGYEFADDRHTCILITPP--ANPCEDGSHTCAPAGQARCVHHGGSTF 876
Query: 200 XXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G+ G G++ C DVDEC++ R C C NTP
Sbjct: 877 SCACLPGYAGDGHQ-----CTDVDECSENR--CHPAATCYNTP 912
Score = 43.6 bits (98), Expect = 0.003
Identities = 41/154 (26%), Positives = 56/154 (36%), Gaps = 25/154 (16%)
Query: 54 NPCFGGRVPCQDLPDGR------YQCGKCPSGFHGNGVECY-RISCRA--NTCFQGVSCE 104
NPC+ G C Y C +C SG+ G+G C C + C C
Sbjct: 762 NPCYDGSHMCDTTARCHPGTGVDYTC-ECASGYQGDGRNCVDENECATGFHRCGPNSVCI 820
Query: 105 ETQYGPKCGSCPTGY--VGDGRQCQHVCDAQKPC---------GRERRCMPKSTSPYYEC 153
+C C +GY D C + PC + RC+ S + C
Sbjct: 821 NLPGSYRC-ECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTF-SC 878
Query: 154 EGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRN 187
C GY +G+ C D+DEC R C +C N
Sbjct: 879 -ACLPGYAGDGHQCTDVDECSENR-CHPAATCYN 910
Score = 35.1 bits (77), Expect = 0.99
Identities = 31/118 (26%), Positives = 46/118 (38%), Gaps = 23/118 (19%)
Query: 204 SQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGG 263
+ G++G G +CVD +ECA G C +C+N P GSY C G
Sbjct: 790 ASGYQGDGR-----NCVDENECATGFHRCGPNSVCINLP-----------GSYRCECRSG 833
Query: 264 HYYVNTTRPCF------DP-DSLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
+ + + C +P + C P+ R G C C G+ G+G C
Sbjct: 834 YEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQC 891
>DQ217942-1|ABB70739.1| 886|Homo sapiens EGF-like module containing
mucin-like hormone receptor-like 1 protein.
Length = 886
Score = 54.8 bits (126), Expect = 1e-06
Identities = 56/216 (25%), Positives = 75/216 (34%), Gaps = 25/216 (11%)
Query: 130 CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEE 189
C C C+ S Y C C G+ TC D+DEC R C + +C N
Sbjct: 136 CLTSSVCPEHSDCVNSMGS--YSCS-CQVGFISRNSTCEDVDECADPRACPEHATCNNTV 192
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPV 249
S G + C D+DEC + CP C NTP
Sbjct: 193 GNYSCFCNPGFESSSGHLSFQG---LKASCEDIDECTE---MCPINSTCTNTP------- 239
Query: 250 SSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTG 309
GSY C C + + + F D V+ D CR+ + CG C G
Sbjct: 240 ----GSYFCT-CHPGFAPSNGQLNF-TDQGVECRDIDECRQDPSTCGPNSICTNALGSYS 293
Query: 310 NGTVCGLDRDLDG-HPDEQLPCNEP--RCKKDNCPD 342
G + G + +G D C +CK+D PD
Sbjct: 294 CGCIAGFHPNPEGSQKDGNFSCQRVLFKCKEDVIPD 329
Score = 43.2 bits (97), Expect = 0.004
Identities = 54/224 (24%), Positives = 76/224 (33%), Gaps = 30/224 (13%)
Query: 37 PGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH---GNGV---ECYRI 90
PG + D C S PC G C++L GRY+C C GF GN +
Sbjct: 74 PGVRCKDIDECSQ--SPQPC-GPNSSCKNL-SGRYKCS-CLDGFSSPTGNDWVPGKPGNF 128
Query: 91 SCR-ANTCFQGVSCEE-----TQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMP 144
SC N C C E G SC G++ C+ V + P
Sbjct: 129 SCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATC 188
Query: 145 KSTSPYYECEGCPSGYQWNGY--------TCVDMDECDLIRPCDDLVSCRNEEXXXXXXX 196
+T Y C P +G+ +C D+DEC + P + +C N
Sbjct: 189 NNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPINS--TCTNTPGSYFCTC 246
Query: 197 XXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVN 240
+ T + C D+DEC + C +C N
Sbjct: 247 HPGFAPSNGQLNFTD---QGVECRDIDECRQDPSTCGPNSICTN 287
>BC059395-1|AAH59395.1| 821|Homo sapiens EMR1 protein protein.
Length = 821
Score = 54.8 bits (126), Expect = 1e-06
Identities = 56/216 (25%), Positives = 75/216 (34%), Gaps = 25/216 (11%)
Query: 130 CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEE 189
C C C+ S Y C C G+ TC D+DEC R C + +C N
Sbjct: 136 CLTSSVCPEHSDCVNSMGS--YSCS-CQVGFISRNSTCEDVDECADPRACPEHATCNNTV 192
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPV 249
S G + C D+DEC + CP C NTP
Sbjct: 193 GNYSCFCNPGFESSSGHLSFQG---LKASCEDIDECTE---MCPINSTCTNTP------- 239
Query: 250 SSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTG 309
GSY C C + + + F D V+ D CR+ + CG C G
Sbjct: 240 ----GSYFCT-CHPGFAPSNGQLNF-TDQGVECRDIDECRQDPSTCGPNSICTNALGSYS 293
Query: 310 NGTVCGLDRDLDG-HPDEQLPCNEP--RCKKDNCPD 342
G + G + +G D C +CK+D PD
Sbjct: 294 CGCIAGFHPNPEGSQKDGNFSCQRVLFKCKEDVIPD 329
Score = 43.2 bits (97), Expect = 0.004
Identities = 54/224 (24%), Positives = 76/224 (33%), Gaps = 30/224 (13%)
Query: 37 PGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH---GNGV---ECYRI 90
PG + D C S PC G C++L GRY+C C GF GN +
Sbjct: 74 PGVRCKDIDECSQ--SPQPC-GPNSSCKNL-SGRYKCS-CLDGFSSPTGNDWVPGKPGNF 128
Query: 91 SCR-ANTCFQGVSCEE-----TQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMP 144
SC N C C E G SC G++ C+ V + P
Sbjct: 129 SCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATC 188
Query: 145 KSTSPYYECEGCPSGYQWNGY--------TCVDMDECDLIRPCDDLVSCRNEEXXXXXXX 196
+T Y C P +G+ +C D+DEC + P + +C N
Sbjct: 189 NNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPINS--TCTNTPGSYFCTC 246
Query: 197 XXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVN 240
+ T + C D+DEC + C +C N
Sbjct: 247 HPGFAPSNGQLNFTD---QGVECRDIDECRQDPSTCGPNSICTN 287
>AJ223500-1|CAA11418.1| 1375|Homo sapiens nidogen-2 protein.
Length = 1375
Score = 54.8 bits (126), Expect = 1e-06
Identities = 42/147 (28%), Positives = 58/147 (39%), Gaps = 15/147 (10%)
Query: 8 DAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQ-TCRTACS-ANPCFGGRVPCQ 64
D T F C C++ +RCE G + +D + TC ANPC G C
Sbjct: 801 DENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCA 860
Query: 65 DLPDGR--------YQCGKCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSC 115
R + C C G+ G+G +C + C N C +C T C C
Sbjct: 861 PAGQARCVHHGGSTFSCA-CLPGYAGDGHQCTDVDECSENRCHPAATCYNTPGSFSC-RC 918
Query: 116 PTGYVGDGRQC-QHVCDAQKPCGRERR 141
GY GDG QC + PC +++R
Sbjct: 919 QPGYYGDGFQCIPDSTSSLTPCEQQQR 945
Score = 48.0 bits (109), Expect = 1e-04
Identities = 47/163 (28%), Positives = 68/163 (41%), Gaps = 27/163 (16%)
Query: 95 NTCFQGVS-CEET-QYGPKCG-----SCPTGYVGDGRQC--QHVCDAQ-KPCGRERRCMP 144
N C+ G C+ T + P G C +GY GDGR C ++ C CG C+
Sbjct: 761 NPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCIN 820
Query: 145 KSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDD---LVSCRNEEXXXXXXXXXX 199
S Y CE C SGY++ + +TC+ + PC+D + +
Sbjct: 821 LPGS--YRCE-CRSGYEFADDRHTCILITPP--ANPCEDGSHTCAPAGQARCVHHGGSTF 875
Query: 200 XXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G+ G G++ C DVDEC++ R C C NTP
Sbjct: 876 SCACLPGYAGDGHQ-----CTDVDECSENR--CHPAATCYNTP 911
Score = 43.6 bits (98), Expect = 0.003
Identities = 41/154 (26%), Positives = 56/154 (36%), Gaps = 25/154 (16%)
Query: 54 NPCFGGRVPCQDLPDGR------YQCGKCPSGFHGNGVECY-RISCRA--NTCFQGVSCE 104
NPC+ G C Y C +C SG+ G+G C C + C C
Sbjct: 761 NPCYDGSHMCDTTARCHPGTGVDYTC-ECASGYQGDGRNCVDENECATGFHRCGPNSVCI 819
Query: 105 ETQYGPKCGSCPTGY--VGDGRQCQHVCDAQKPC---------GRERRCMPKSTSPYYEC 153
+C C +GY D C + PC + RC+ S + C
Sbjct: 820 NLPGSYRC-ECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTF-SC 877
Query: 154 EGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRN 187
C GY +G+ C D+DEC R C +C N
Sbjct: 878 -ACLPGYAGDGHQCTDVDECSENR-CHPAATCYN 909
Score = 35.1 bits (77), Expect = 0.99
Identities = 31/118 (26%), Positives = 46/118 (38%), Gaps = 23/118 (19%)
Query: 204 SQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGG 263
+ G++G G +CVD +ECA G C +C+N P GSY C G
Sbjct: 789 ASGYQGDGR-----NCVDENECATGFHRCGPNSVCINLP-----------GSYRCECRSG 832
Query: 264 HYYVNTTRPCF------DP-DSLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
+ + + C +P + C P+ R G C C G+ G+G C
Sbjct: 833 YEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQC 890
>AB065918-1|BAC06133.1| 929|Homo sapiens seven transmembrane helix
receptor protein.
Length = 929
Score = 54.8 bits (126), Expect = 1e-06
Identities = 56/216 (25%), Positives = 75/216 (34%), Gaps = 25/216 (11%)
Query: 130 CDAQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEE 189
C C C+ S Y C C G+ TC D+DEC R C + +C N
Sbjct: 154 CLTSSVCPEHSDCVNSMGS--YSCS-CQVGFISRNSTCEDVDECADPRACPEHATCNNTV 210
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPV 249
S G + C D+DEC + CP C NTP
Sbjct: 211 GNYSCFCNPGFESSSGHLSFQG---LKASCEDIDECTE---MCPINSTCTNTP------- 257
Query: 250 SSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTG 309
GSY C C + + + F D V+ D CR+ + CG C G
Sbjct: 258 ----GSYFCT-CHPGFAPSNGQLNF-TDQGVECRDIDECRQDPSTCGPNSICTNALGSYS 311
Query: 310 NGTVCGLDRDLDG-HPDEQLPCNEP--RCKKDNCPD 342
G + G + +G D C +CK+D PD
Sbjct: 312 CGCIAGFHPNPEGSQKDGNFSCQRVLFKCKEDVIPD 347
Score = 43.2 bits (97), Expect = 0.004
Identities = 54/224 (24%), Positives = 76/224 (33%), Gaps = 30/224 (13%)
Query: 37 PGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH---GNGV---ECYRI 90
PG + D C S PC G C++L GRY+C C GF GN +
Sbjct: 92 PGVRCKDIDECSQ--SPQPC-GPNSSCKNL-SGRYKCS-CLDGFSSPTGNDWVPGKPGNF 146
Query: 91 SCR-ANTCFQGVSCEE-----TQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGRERRCMP 144
SC N C C E G SC G++ C+ V + P
Sbjct: 147 SCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATC 206
Query: 145 KSTSPYYECEGCPSGYQWNGY--------TCVDMDECDLIRPCDDLVSCRNEEXXXXXXX 196
+T Y C P +G+ +C D+DEC + P + +C N
Sbjct: 207 NNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPINS--TCTNTPGSYFCTC 264
Query: 197 XXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVN 240
+ T + C D+DEC + C +C N
Sbjct: 265 HPGFAPSNGQLNFTD---QGVECRDIDECRQDPSTCGPNSICTN 305
>AB009799-1|BAA24112.1| 1376|Homo sapiens osteonidogen protein.
Length = 1376
Score = 54.8 bits (126), Expect = 1e-06
Identities = 42/147 (28%), Positives = 58/147 (39%), Gaps = 15/147 (10%)
Query: 8 DAGSMVTPFKLC-VGERCVDTDQGFRCERCPGSQTSDGQ-TCRTACS-ANPCFGGRVPCQ 64
D T F C C++ +RCE G + +D + TC ANPC G C
Sbjct: 802 DENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCA 861
Query: 65 DLPDGR--------YQCGKCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSC 115
R + C C G+ G+G +C + C N C +C T C C
Sbjct: 862 PAGQARCVHHGGSTFSCA-CLPGYAGDGHQCTDVDECSENRCHPAATCYNTPGSFSC-RC 919
Query: 116 PTGYVGDGRQC-QHVCDAQKPCGRERR 141
GY GDG QC + PC +++R
Sbjct: 920 QPGYYGDGFQCIPDSTSSLTPCEQQQR 946
Score = 48.0 bits (109), Expect = 1e-04
Identities = 47/163 (28%), Positives = 68/163 (41%), Gaps = 27/163 (16%)
Query: 95 NTCFQGVS-CEET-QYGPKCG-----SCPTGYVGDGRQC--QHVCDAQ-KPCGRERRCMP 144
N C+ G C+ T + P G C +GY GDGR C ++ C CG C+
Sbjct: 762 NPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCIN 821
Query: 145 KSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDD---LVSCRNEEXXXXXXXXXX 199
S Y CE C SGY++ + +TC+ + PC+D + +
Sbjct: 822 LPGS--YRCE-CRSGYEFADDRHTCILITPP--ANPCEDGSHTCAPAGQARCVHHGGSTF 876
Query: 200 XXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G+ G G++ C DVDEC++ R C C NTP
Sbjct: 877 SCACLPGYAGDGHQ-----CTDVDECSENR--CHPAATCYNTP 912
Score = 43.6 bits (98), Expect = 0.003
Identities = 41/154 (26%), Positives = 56/154 (36%), Gaps = 25/154 (16%)
Query: 54 NPCFGGRVPCQDLPDGR------YQCGKCPSGFHGNGVECY-RISCRA--NTCFQGVSCE 104
NPC+ G C Y C +C SG+ G+G C C + C C
Sbjct: 762 NPCYDGSHMCDTTARCHPGTGVDYTC-ECASGYQGDGRNCVDENECATGFHRCGPNSVCI 820
Query: 105 ETQYGPKCGSCPTGY--VGDGRQCQHVCDAQKPC---------GRERRCMPKSTSPYYEC 153
+C C +GY D C + PC + RC+ S + C
Sbjct: 821 NLPGSYRC-ECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTF-SC 878
Query: 154 EGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRN 187
C GY +G+ C D+DEC R C +C N
Sbjct: 879 -ACLPGYAGDGHQCTDVDECSENR-CHPAATCYN 910
Score = 35.1 bits (77), Expect = 0.99
Identities = 31/118 (26%), Positives = 46/118 (38%), Gaps = 23/118 (19%)
Query: 204 SQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGG 263
+ G++G G +CVD +ECA G C +C+N P GSY C G
Sbjct: 790 ASGYQGDGR-----NCVDENECATGFHRCGPNSVCINLP-----------GSYRCECRSG 833
Query: 264 HYYVNTTRPCF------DP-DSLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
+ + + C +P + C P+ R G C C G+ G+G C
Sbjct: 834 YEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQC 891
>D87433-1|BAA13377.2| 2589|Homo sapiens KIAA0246 protein protein.
Length = 2589
Score = 54.4 bits (125), Expect = 2e-06
Identities = 52/217 (23%), Positives = 71/217 (32%), Gaps = 24/217 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C +G C C + G+ C+ C C G + G Q G C GF G
Sbjct: 777 CFPDYKGIACHIC-SNPNKHGEQCQEDCG---CVHGLCDNRPGSGGVCQQGTCAPGFSGR 832
Query: 84 GVECYRISCR----ANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP---- 135
C A C C + +C C G+ GDG C P
Sbjct: 833 FCNESMGDCGPTGLAQHCHLHARCVSQEGVARC-RCLDGFEGDGFSCTPSNPCSHPDRGG 891
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXX 195
C C+P S ++ C C G+ +G CV +DEC+L D C +
Sbjct: 892 CSENAECVPGSLGTHH-CT-CHKGWSGDGRVCVAIDECEL----DVRGGCHTDALCSYVG 945
Query: 196 XXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC 232
G+ G G + C +D C G C
Sbjct: 946 PGQSRCTCKLGFAGDGYQ-----CSPIDPCRAGNGGC 977
Score = 54.4 bits (125), Expect = 2e-06
Identities = 44/167 (26%), Positives = 62/167 (37%), Gaps = 22/167 (13%)
Query: 29 QGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECY 88
QG RC+ Q C C N C G C C +G+ GNG+ C
Sbjct: 1426 QGLRCD-----QKITSPQCPRKCDPN------ANCVQDSAGASTCA-CAAGYSGNGIFCS 1473
Query: 89 RISCRANT---CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA---QKPCGRERRC 142
+ A+ C +C + G + +C GY+GDG CQ + C C
Sbjct: 1474 EVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAEC 1533
Query: 143 MPKSTSPYYECEGCPSGYQWNGY-TCVDMDECDLIR-PCDDLVSCRN 187
+P T P C GY +G TC +D C C +C++
Sbjct: 1534 IP--TGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKS 1578
Score = 50.0 bits (114), Expect = 3e-05
Identities = 41/152 (26%), Positives = 57/152 (37%), Gaps = 15/152 (9%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C + +G C+ C G C++ CS C G C P G C C +G+ G
Sbjct: 157 CQENFRGSACQECQDPNRF-GPDCQSVCS---CVHG--VCNHGPRGDGSC-LCFAGYTGP 209
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA-QKPCGRERRC 142
+ C+ C Q C P C C GY G +C+ PC +C
Sbjct: 210 HCDQELPVCQELRCPQNTQCSAE--APSC-RCLPGYTQQGSECRAPNPCWPSPCSLLAQC 266
Query: 143 MPKSTSPYYECE-GCPSGYQWNGYTCVDMDEC 173
S SP + + CP Y +G C+ D C
Sbjct: 267 ---SVSPKGQAQCHCPENYHGDGMVCLPKDPC 295
Score = 48.0 bits (109), Expect = 1e-04
Identities = 85/310 (27%), Positives = 106/310 (34%), Gaps = 59/310 (19%)
Query: 17 KLCVGERCVDTDQGFRCERCPGSQTS--DGQ-TCRTACSANPCFGGRVPCQDLPDGRYQC 73
K V + C G RC CPG + +G TC N G CQ+ G C
Sbjct: 112 KQVVQKACCPGYWGSRCHECPGGAETPCNGHGTCLDGMDRN----GTCVCQENFRGS-AC 166
Query: 74 GKC--PSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
+C P+ F G +C + C +C GV C G C GY G H CD
Sbjct: 167 QECQDPNRF---GPDCQSV-C---SCVHGV-CNHGPRGDGSCLCFAGYTG-----PH-CD 212
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCP--SGYQWNGYTCVDMDECDLIRPCDDLVSCRNEE 189
+ P +E RC P++T E C GY G C + C PC L C
Sbjct: 213 QELPVCQELRC-PQNTQCSAEAPSCRCLPGYTQQGSECRAPNPC-WPSPCSLLAQC---- 266
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCP-RGRLCVNTPQYPSNP 248
+ + G G C+ D C D CP LCV Q P
Sbjct: 267 --SVSPKGQAQCHCPENYHGDGMV-----CLPKDPCTDNLGGCPSNSTLCVY--QKPG-- 315
Query: 249 VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQ-KCVCN 304
Q C P N + CF C P C R +A C G+ CVC
Sbjct: 316 ----QAFCTCRPGLVSINSNASAGCF------AFCSPFSCDR-SATCQVTADGKTSCVCR 364
Query: 305 TGWTGNGTVC 314
G+G C
Sbjct: 365 ESEVGDGRAC 374
Score = 45.2 bits (102), Expect = 0.001
Identities = 45/168 (26%), Positives = 60/168 (35%), Gaps = 24/168 (14%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C G C+ CPG +S PC R C D G QC C SGF G
Sbjct: 1978 CCPGHYGSECQACPGGPSS------------PC-SDRGVCMDGMSGSGQC-LCRSGFAGT 2023
Query: 84 GVE-----CYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGR 138
E + C+A C C+E G C G+ G +C+ + Q C
Sbjct: 2024 ACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGP--RCEVQLELQPVC-- 2079
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDLVSC 185
C P++ C GY+ +G C D C D C + +C
Sbjct: 2080 TPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANC 2127
Score = 43.6 bits (98), Expect = 0.003
Identities = 32/110 (29%), Positives = 44/110 (40%), Gaps = 8/110 (7%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA--CSANPCFGGRVP--CQDLPDGRYQCGKCPSG 79
CV G C + DG+ C C + G C + G+ +C C G
Sbjct: 898 CVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDVRGGCHTDALCSYVGPGQSRC-TCKLG 956
Query: 80 FHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQC 126
F G+G +C I CRA C +C G + +CP G+ GDG C
Sbjct: 957 FAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDGFSC 1006
Score = 36.7 bits (81), Expect = 0.33
Identities = 30/104 (28%), Positives = 37/104 (35%), Gaps = 10/104 (9%)
Query: 30 GFRCERCPGSQTSDGQTCRTACSANPCFGG---RVPCQDLPDGRYQCGKCPSGFHGNGVE 86
G CE C DG+ C A GG C + G C + G+G
Sbjct: 2092 GNSCE-CSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQV--GTMVTCTCLPDYEGDGWS 2148
Query: 87 CY-RISC---RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQC 126
C R C C + +C T + C GYVGDG QC
Sbjct: 2149 CRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQC 2192
Score = 35.5 bits (78), Expect = 0.75
Identities = 60/251 (23%), Positives = 78/251 (31%), Gaps = 46/251 (18%)
Query: 22 ERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
E+CV+ + FRC + G Q D T R +C F C + Q C GF
Sbjct: 1289 EKCVNCTRRFRCTQ--GFQLQD--TPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCCPGFF 1344
Query: 82 GN----------GVECYRISCRANTCFQG-VSCEETQYGPKCGSCPTGYVGDGRQCQHVC 130
G GV C+ G C E +G C C G G C VC
Sbjct: 1345 GTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPN--CTGVC 1402
Query: 131 DAQKPCGRERRCMPKSTSPYYECEG-CPSGYQWNGYTC---VDMDECDLIRPCDDLVSCR 186
D C + +G C W G C + +C R CD +C
Sbjct: 1403 D----------CAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCP--RKCDPNANCV 1450
Query: 187 NEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPS 246
+ G+ G G C +VD CA G C C T P
Sbjct: 1451 QDSAGASTCACAA------GYSGNGI-----FCSEVDPCAHGHGGCSPHANC--TKVAPG 1497
Query: 247 NPVSSLQGSYI 257
+ Q Y+
Sbjct: 1498 QRTCTCQDGYM 1508
Score = 33.9 bits (74), Expect = 2.3
Identities = 15/32 (46%), Positives = 19/32 (59%), Gaps = 1/32 (3%)
Query: 293 AVCGFGQKCVCNTGWTGNGTVCGL-DRDLDGH 323
AVC G C C+ G+ G+G VC + D DGH
Sbjct: 2087 AVCRAGNSCECSLGYEGDGRVCTVADLCQDGH 2118
>DQ786774-1|ABG91068.1| 2570|Homo sapiens FEX1 protein.
Length = 2570
Score = 54.4 bits (125), Expect = 2e-06
Identities = 52/217 (23%), Positives = 71/217 (32%), Gaps = 24/217 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C +G C C + G+ C+ C C G + G Q G C GF G
Sbjct: 758 CFPDYKGIACHIC-SNPNKHGEQCQEDCG---CVHGLCDNRPGSGGVCQQGTCAPGFSGR 813
Query: 84 GVECYRISCR----ANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP---- 135
C A C C + +C C G+ GDG C P
Sbjct: 814 FCNESMGDCGPTGLAQHCHLHARCVSQEGVARC-RCLDGFEGDGFSCTPSNPCSHPDRGG 872
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXX 195
C C+P S ++ C C G+ +G CV +DEC+L D C +
Sbjct: 873 CSENAECVPGSLGTHH-CT-CHKGWSGDGRVCVAIDECEL----DVRGGCHTDALCSYVG 926
Query: 196 XXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC 232
G+ G G + C +D C G C
Sbjct: 927 PGQSRCTCKLGFAGDGYQ-----CSPIDPCRAGNGGC 958
Score = 54.4 bits (125), Expect = 2e-06
Identities = 44/167 (26%), Positives = 62/167 (37%), Gaps = 22/167 (13%)
Query: 29 QGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECY 88
QG RC+ Q C C N C G C C +G+ GNG+ C
Sbjct: 1407 QGLRCD-----QKITSPQCPRKCDPN------ANCVQDSAGASTCA-CAAGYSGNGIFCS 1454
Query: 89 RISCRANT---CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA---QKPCGRERRC 142
+ A+ C +C + G + +C GY+GDG CQ + C C
Sbjct: 1455 EVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAEC 1514
Query: 143 MPKSTSPYYECEGCPSGYQWNGY-TCVDMDECDLIR-PCDDLVSCRN 187
+P T P C GY +G TC +D C C +C++
Sbjct: 1515 IP--TGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKS 1559
Score = 50.0 bits (114), Expect = 3e-05
Identities = 41/152 (26%), Positives = 57/152 (37%), Gaps = 15/152 (9%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C + +G C+ C G C++ CS C G C P G C C +G+ G
Sbjct: 138 CQENFRGSACQECQDPNRF-GPDCQSVCS---CVHG--VCNHGPRGDGSC-LCFAGYTGP 190
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA-QKPCGRERRC 142
+ C+ C Q C P C C GY G +C+ PC +C
Sbjct: 191 HCDQELPVCQELRCPQNTQCSAE--APSC-RCLPGYTQQGSECRAPNPCWPSPCSLLAQC 247
Query: 143 MPKSTSPYYECE-GCPSGYQWNGYTCVDMDEC 173
S SP + + CP Y +G C+ D C
Sbjct: 248 ---SVSPKGQAQCHCPENYHGDGMVCLPKDPC 276
Score = 48.0 bits (109), Expect = 1e-04
Identities = 85/310 (27%), Positives = 106/310 (34%), Gaps = 59/310 (19%)
Query: 17 KLCVGERCVDTDQGFRCERCPGSQTS--DGQ-TCRTACSANPCFGGRVPCQDLPDGRYQC 73
K V + C G RC CPG + +G TC N G CQ+ G C
Sbjct: 93 KQVVQKACCPGYWGSRCHECPGGAETPCNGHGTCLDGMDRN----GTCVCQENFRGS-AC 147
Query: 74 GKC--PSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
+C P+ F G +C + C +C GV C G C GY G H CD
Sbjct: 148 QECQDPNRF---GPDCQSV-C---SCVHGV-CNHGPRGDGSCLCFAGYTG-----PH-CD 193
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCP--SGYQWNGYTCVDMDECDLIRPCDDLVSCRNEE 189
+ P +E RC P++T E C GY G C + C PC L C
Sbjct: 194 QELPVCQELRC-PQNTQCSAEAPSCRCLPGYTQQGSECRAPNPC-WPSPCSLLAQC---- 247
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCP-RGRLCVNTPQYPSNP 248
+ + G G C+ D C D CP LCV Q P
Sbjct: 248 --SVSPKGQAQCHCPENYHGDGMV-----CLPKDPCTDNLGGCPSNSTLCVY--QKPG-- 296
Query: 249 VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQ-KCVCN 304
Q C P N + CF C P C R +A C G+ CVC
Sbjct: 297 ----QAFCTCRPGLVSINSNASAGCF------AFCSPFSCDR-SATCQVTADGKTSCVCR 345
Query: 305 TGWTGNGTVC 314
G+G C
Sbjct: 346 ESEVGDGRAC 355
Score = 45.2 bits (102), Expect = 0.001
Identities = 45/168 (26%), Positives = 60/168 (35%), Gaps = 24/168 (14%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C G C+ CPG +S PC R C D G QC C SGF G
Sbjct: 1959 CCPGHYGSECQACPGGPSS------------PC-SDRGVCMDGMSGSGQC-LCRSGFAGT 2004
Query: 84 GVE-----CYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGR 138
E + C+A C C+E G C G+ G +C+ + Q C
Sbjct: 2005 ACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGP--RCEVQLELQPVC-- 2060
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDLVSC 185
C P++ C GY+ +G C D C D C + +C
Sbjct: 2061 TPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANC 2108
Score = 43.6 bits (98), Expect = 0.003
Identities = 32/110 (29%), Positives = 44/110 (40%), Gaps = 8/110 (7%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA--CSANPCFGGRVP--CQDLPDGRYQCGKCPSG 79
CV G C + DG+ C C + G C + G+ +C C G
Sbjct: 879 CVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDVRGGCHTDALCSYVGPGQSRC-TCKLG 937
Query: 80 FHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQC 126
F G+G +C I CRA C +C G + +CP G+ GDG C
Sbjct: 938 FAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDGFSC 987
Score = 36.7 bits (81), Expect = 0.33
Identities = 30/104 (28%), Positives = 37/104 (35%), Gaps = 10/104 (9%)
Query: 30 GFRCERCPGSQTSDGQTCRTACSANPCFGG---RVPCQDLPDGRYQCGKCPSGFHGNGVE 86
G CE C DG+ C A GG C + G C + G+G
Sbjct: 2073 GNSCE-CSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQV--GTMVTCTCLPDYEGDGWS 2129
Query: 87 CY-RISC---RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQC 126
C R C C + +C T + C GYVGDG QC
Sbjct: 2130 CRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQC 2173
Score = 35.5 bits (78), Expect = 0.75
Identities = 60/251 (23%), Positives = 78/251 (31%), Gaps = 46/251 (18%)
Query: 22 ERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
E+CV+ + FRC + G Q D T R +C F C + Q C GF
Sbjct: 1270 EKCVNCTRRFRCTQ--GFQLQD--TPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCCPGFF 1325
Query: 82 GN----------GVECYRISCRANTCFQG-VSCEETQYGPKCGSCPTGYVGDGRQCQHVC 130
G GV C+ G C E +G C C G G C VC
Sbjct: 1326 GTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPN--CTGVC 1383
Query: 131 DAQKPCGRERRCMPKSTSPYYECEG-CPSGYQWNGYTC---VDMDECDLIRPCDDLVSCR 186
D C + +G C W G C + +C R CD +C
Sbjct: 1384 D----------CAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCP--RKCDPNANCV 1431
Query: 187 NEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPS 246
+ G+ G G C +VD CA G C C T P
Sbjct: 1432 QDSAGASTCACAA------GYSGNGI-----FCSEVDPCAHGHGGCSPHANC--TKVAPG 1478
Query: 247 NPVSSLQGSYI 257
+ Q Y+
Sbjct: 1479 QRTCTCQDGYM 1489
Score = 33.9 bits (74), Expect = 2.3
Identities = 15/32 (46%), Positives = 19/32 (59%), Gaps = 1/32 (3%)
Query: 293 AVCGFGQKCVCNTGWTGNGTVCGL-DRDLDGH 323
AVC G C C+ G+ G+G VC + D DGH
Sbjct: 2068 AVCRAGNSCECSLGYEGDGRVCTVADLCQDGH 2099
>BC027939-1|AAH27939.1| 600|Homo sapiens SNED1 protein protein.
Length = 600
Score = 54.4 bits (125), Expect = 2e-06
Identities = 39/115 (33%), Positives = 52/115 (45%), Gaps = 11/115 (9%)
Query: 48 RTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQ 107
R C A+PC G C++LP G Y C +CP+GF G E +C ++ C G CE
Sbjct: 27 RDECRAHPCRNGG-SCRNLP-GAYVC-RCPAGFVGVHCETEVDACDSSPCQHGGRCESGG 83
Query: 108 YGPKCGSCPTGYVGDGRQCQHVCDA--QKPCGRERRCMPKSTSPYYECEGCPSGY 160
C CP + G C+ V D PCG C+ + S + C C GY
Sbjct: 84 GAYLC-VCPESFF--GYHCETVSDPCFSSPCGGRGYCLASNGS--HSCT-CKVGY 132
>AJ295142-1|CAC82720.1| 652|Homo sapiens C1q receptor protein
protein.
Length = 652
Score = 54.4 bits (125), Expect = 2e-06
Identities = 51/161 (31%), Positives = 71/161 (44%), Gaps = 24/161 (14%)
Query: 28 DQGFRCERCPGSQTSDGQ-TC--RTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH--G 82
D F C PG + D TC R CS++PC GG C P G+ +CP G+
Sbjct: 280 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGG-ATCALGPHGKNYTCRCPQGYQLDS 338
Query: 83 NGVECYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGYV--GDGR-QCQHVCD---AQKP 135
+ ++C + C+ + C Q C T G +C C GY G G CQ V + + P
Sbjct: 339 SQLDCVDVDECQDSPCAQ--ECVNTPGGFRC-ECWVGYEPGGPGEGACQDVDECALGRSP 395
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQW---NGYTCVDMDEC 173
C + C +T + C C GY +G C D+DEC
Sbjct: 396 CA--QGC--TNTDGSFHC-SCEEGYVLAGEDGTQCQDVDEC 431
Score = 42.3 bits (95), Expect = 0.007
Identities = 56/187 (29%), Positives = 66/187 (35%), Gaps = 30/187 (16%)
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLIRPCDDLVSCRNEE 189
+ PC C Y C CP GYQ + CVD+DEC PC C N
Sbjct: 307 SSSPCRGGATCALGPHGKNYTCR-CPQGYQLDSSQLDCVDVDECQ-DSPCAQ--ECVNTP 362
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPV 249
G G G C DVDECA GR+ C +G C NT +
Sbjct: 363 GGFRCECWVGY---EPGGPGEGA------CQDVDECALGRSPCAQG--CTNT---DGSFH 408
Query: 250 SSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTGW-- 307
S + Y+ G + C P + CD S C FN F C C GW
Sbjct: 409 CSCEEGYVLAGEDGTQCQDVDE-CVGPGGPL--CD-SLC--FNTQGSF--HCGCLPGWVL 460
Query: 308 TGNGTVC 314
NG C
Sbjct: 461 APNGVSC 467
Score = 32.7 bits (71), Expect = 5.3
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 7/63 (11%)
Query: 22 ERCVDTDQGFRCERCPGSQTSDGQTCRTAC-SANPCFGGRVPCQD---LPDGRYQCGKCP 77
+ CV+T GFRCE G + G AC + C GR PC DG + C C
Sbjct: 356 QECVNTPGGFRCECWVGYE--PGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHC-SCE 412
Query: 78 SGF 80
G+
Sbjct: 413 EGY 415
>AJ275213-1|CAB61827.1| 2570|Homo sapiens stabilin-1 protein.
Length = 2570
Score = 54.4 bits (125), Expect = 2e-06
Identities = 44/167 (26%), Positives = 62/167 (37%), Gaps = 22/167 (13%)
Query: 29 QGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECY 88
QG RC+ Q C C N C G C C +G+ GNG+ C
Sbjct: 1407 QGLRCD-----QKITSPQCPRKCDPN------ANCVQDSAGASTCA-CAAGYSGNGIFCS 1454
Query: 89 RISCRANT---CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA---QKPCGRERRC 142
+ A+ C +C + G + +C GY+GDG CQ + C C
Sbjct: 1455 EVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAEC 1514
Query: 143 MPKSTSPYYECEGCPSGYQWNGY-TCVDMDECDLIR-PCDDLVSCRN 187
+P T P C GY +G TC +D C C +C++
Sbjct: 1515 IP--TGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKS 1559
Score = 53.6 bits (123), Expect = 3e-06
Identities = 52/217 (23%), Positives = 71/217 (32%), Gaps = 24/217 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C +G C C + G+ C+ C C G + G Q G C GF G
Sbjct: 758 CFPDYKGIACHIC-SNPNKHGEQCQEDCG---CVHGLCDNRPGSGGVCQQGTCAPGFSGR 813
Query: 84 GVECYRISCR----ANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP---- 135
C A C C + +C C G+ GDG C P
Sbjct: 814 FCNESMGDCGPTGLAQHCHLHARCVSQEGVARC-RCLDGFEGDGFSCTPSNPCSHPDRGG 872
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXX 195
C C+P S ++ C C G+ +G CV +DEC+L D C +
Sbjct: 873 CSENAECVPGSLGTHH-CT-CHKGWSGDGRVCVAIDECEL----DVGGGCHTDALCSYVG 926
Query: 196 XXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC 232
G+ G G + C +D C G C
Sbjct: 927 PGQSRCTCKLGFAGDGYQ-----CSPIDPCRAGNGGC 958
Score = 50.0 bits (114), Expect = 3e-05
Identities = 41/152 (26%), Positives = 57/152 (37%), Gaps = 15/152 (9%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C + +G C+ C G C++ CS C G C P G C C +G+ G
Sbjct: 138 CQENFRGSACQECQDPNRF-GPDCQSVCS---CVHG--VCNHGPRGDGSC-LCFAGYTGP 190
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA-QKPCGRERRC 142
+ C+ C Q C P C C GY G +C+ PC +C
Sbjct: 191 HCDQELPVCQELRCPQNTQCSAE--APSC-RCLPGYTQQGSECRAPNPCWPSPCSLLAQC 247
Query: 143 MPKSTSPYYECE-GCPSGYQWNGYTCVDMDEC 173
S SP + + CP Y +G C+ D C
Sbjct: 248 ---SVSPKGQAQCHCPENYHGDGMVCLPKDPC 276
Score = 48.0 bits (109), Expect = 1e-04
Identities = 85/310 (27%), Positives = 106/310 (34%), Gaps = 59/310 (19%)
Query: 17 KLCVGERCVDTDQGFRCERCPGSQTS--DGQ-TCRTACSANPCFGGRVPCQDLPDGRYQC 73
K V + C G RC CPG + +G TC N G CQ+ G C
Sbjct: 93 KQVVQKACCPGYWGSRCHECPGGAETPCNGHGTCLDGMDRN----GTCVCQENFRGS-AC 147
Query: 74 GKC--PSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
+C P+ F G +C + C +C GV C G C GY G H CD
Sbjct: 148 QECQDPNRF---GPDCQSV-C---SCVHGV-CNHGPRGDGSCLCFAGYTG-----PH-CD 193
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCP--SGYQWNGYTCVDMDECDLIRPCDDLVSCRNEE 189
+ P +E RC P++T E C GY G C + C PC L C
Sbjct: 194 QELPVCQELRC-PQNTQCSAEAPSCRCLPGYTQQGSECRAPNPC-WPSPCSLLAQC---- 247
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCP-RGRLCVNTPQYPSNP 248
+ + G G C+ D C D CP LCV Q P
Sbjct: 248 --SVSPKGQAQCHCPENYHGDGMV-----CLPKDPCTDNLGGCPSNSTLCVY--QKPG-- 296
Query: 249 VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQ-KCVCN 304
Q C P N + CF C P C R +A C G+ CVC
Sbjct: 297 ----QAFCTCRPGLVSINSNASAGCF------AFCSPFSCDR-SATCQVTADGKTSCVCR 345
Query: 305 TGWTGNGTVC 314
G+G C
Sbjct: 346 ESEVGDGRAC 355
Score = 45.2 bits (102), Expect = 0.001
Identities = 45/168 (26%), Positives = 60/168 (35%), Gaps = 24/168 (14%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C G C+ CPG +S PC R C D G QC C SGF G
Sbjct: 1959 CCPGHYGSECQACPGGPSS------------PC-SDRGVCMDGMSGSGQC-LCRSGFAGT 2004
Query: 84 GVE-----CYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGR 138
E + C+A C C+E G C G+ G +C+ + Q C
Sbjct: 2005 ACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGP--RCEVQLELQPVC-- 2060
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDLVSC 185
C P++ C GY+ +G C D C D C + +C
Sbjct: 2061 TPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANC 2108
Score = 44.8 bits (101), Expect = 0.001
Identities = 32/110 (29%), Positives = 43/110 (39%), Gaps = 8/110 (7%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVP----CQDLPDGRYQCGKCPSG 79
CV G C + DG+ C GG C + G+ +C C G
Sbjct: 879 CVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDVGGGCHTDALCSYVGPGQSRC-TCKLG 937
Query: 80 FHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQC 126
F G+G +C I CRA C +C G + +CP G+ GDG C
Sbjct: 938 FAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDGFSC 987
Score = 36.7 bits (81), Expect = 0.33
Identities = 30/104 (28%), Positives = 37/104 (35%), Gaps = 10/104 (9%)
Query: 30 GFRCERCPGSQTSDGQTCRTACSANPCFGG---RVPCQDLPDGRYQCGKCPSGFHGNGVE 86
G CE C DG+ C A GG C + G C + G+G
Sbjct: 2073 GNSCE-CSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQV--GTMVTCTCLPDYEGDGWS 2129
Query: 87 CY-RISC---RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQC 126
C R C C + +C T + C GYVGDG QC
Sbjct: 2130 CRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQC 2173
Score = 35.5 bits (78), Expect = 0.75
Identities = 60/251 (23%), Positives = 78/251 (31%), Gaps = 46/251 (18%)
Query: 22 ERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
E+CV+ + FRC + G Q D T R +C F C + Q C GF
Sbjct: 1270 EKCVNCTRRFRCTQ--GFQLQD--TPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCCPGFF 1325
Query: 82 GN----------GVECYRISCRANTCFQG-VSCEETQYGPKCGSCPTGYVGDGRQCQHVC 130
G GV C+ G C E +G C C G G C VC
Sbjct: 1326 GTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPN--CTGVC 1383
Query: 131 DAQKPCGRERRCMPKSTSPYYECEG-CPSGYQWNGYTC---VDMDECDLIRPCDDLVSCR 186
D C + +G C W G C + +C R CD +C
Sbjct: 1384 D----------CAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCP--RKCDPNANCV 1431
Query: 187 NEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPS 246
+ G+ G G C +VD CA G C C T P
Sbjct: 1432 QDSAGASTCACAA------GYSGNGI-----FCSEVDPCAHGHGGCSPHANC--TKVAPG 1478
Query: 247 NPVSSLQGSYI 257
+ Q Y+
Sbjct: 1479 QRTCTCQDGYM 1489
Score = 33.9 bits (74), Expect = 2.3
Identities = 15/32 (46%), Positives = 19/32 (59%), Gaps = 1/32 (3%)
Query: 293 AVCGFGQKCVCNTGWTGNGTVCGL-DRDLDGH 323
AVC G C C+ G+ G+G VC + D DGH
Sbjct: 2068 AVCRAGNSCECSLGYEGDGRVCTVADLCQDGH 2099
>AB052956-1|BAC15606.1| 2570|Homo sapiens FELE-1 protein.
Length = 2570
Score = 54.4 bits (125), Expect = 2e-06
Identities = 52/217 (23%), Positives = 71/217 (32%), Gaps = 24/217 (11%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C +G C C + G+ C+ C C G + G Q G C GF G
Sbjct: 758 CFPDYKGIACHIC-SNPNKHGEQCQEDCG---CVHGLCDNRPGSGGVCQQGTCAPGFSGR 813
Query: 84 GVECYRISCR----ANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKP---- 135
C A C C + +C C G+ GDG C P
Sbjct: 814 FCNESMGDCGPTGLAQHCHLHARCVSQEGVARC-RCLDGFEGDGFSCTPSNPCSHPDRGG 872
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXX 195
C C+P S ++ C C G+ +G CV +DEC+L D C +
Sbjct: 873 CSENAECVPGSLGTHH-CT-CHKGWSGDGRVCVAIDECEL----DVRGGCHTDALCSYVG 926
Query: 196 XXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANC 232
G+ G G + C +D C G C
Sbjct: 927 PGQSRCTCKLGFAGDGYQ-----CSPIDPCRAGNGGC 958
Score = 54.4 bits (125), Expect = 2e-06
Identities = 44/167 (26%), Positives = 62/167 (37%), Gaps = 22/167 (13%)
Query: 29 QGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECY 88
QG RC+ Q C C N C G C C +G+ GNG+ C
Sbjct: 1407 QGLRCD-----QKITSPQCPRKCDPN------ANCVQDSAGASTCA-CAAGYSGNGIFCS 1454
Query: 89 RISCRANT---CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA---QKPCGRERRC 142
+ A+ C +C + G + +C GY+GDG CQ + C C
Sbjct: 1455 EVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAEC 1514
Query: 143 MPKSTSPYYECEGCPSGYQWNGY-TCVDMDECDLIR-PCDDLVSCRN 187
+P T P C GY +G TC +D C C +C++
Sbjct: 1515 IP--TGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKS 1559
Score = 50.0 bits (114), Expect = 3e-05
Identities = 41/152 (26%), Positives = 57/152 (37%), Gaps = 15/152 (9%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C + +G C+ C G C++ CS C G C P G C C +G+ G
Sbjct: 138 CQENFRGSACQECQDPNRF-GPDCQSVCS---CVHG--VCNHGPRGDGSC-LCFAGYTGP 190
Query: 84 GVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDA-QKPCGRERRC 142
+ C+ C Q C P C C GY G +C+ PC +C
Sbjct: 191 HCDQELPVCQELRCPQNTQCSAE--APSC-RCLPGYTQQGSECRAPNPCWPSPCSLLAQC 247
Query: 143 MPKSTSPYYECE-GCPSGYQWNGYTCVDMDEC 173
S SP + + CP Y +G C+ D C
Sbjct: 248 ---SVSPKGQAQCHCPENYHGDGMVCLPKDPC 276
Score = 48.0 bits (109), Expect = 1e-04
Identities = 85/310 (27%), Positives = 106/310 (34%), Gaps = 59/310 (19%)
Query: 17 KLCVGERCVDTDQGFRCERCPGSQTS--DGQ-TCRTACSANPCFGGRVPCQDLPDGRYQC 73
K V + C G RC CPG + +G TC N G CQ+ G C
Sbjct: 93 KQVVQKACCPGYWGSRCHECPGGAETPCNGHGTCLDGMDRN----GTCVCQENFRGS-AC 147
Query: 74 GKC--PSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD 131
+C P+ F G +C + C +C GV C G C GY G H CD
Sbjct: 148 QECQDPNRF---GPDCQSV-C---SCVHGV-CNHGPRGDGSCLCFAGYTG-----PH-CD 193
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCP--SGYQWNGYTCVDMDECDLIRPCDDLVSCRNEE 189
+ P +E RC P++T E C GY G C + C PC L C
Sbjct: 194 QELPVCQELRC-PQNTQCSAEAPSCRCLPGYTQQGSECRAPNPC-WPSPCSLLAQC---- 247
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCP-RGRLCVNTPQYPSNP 248
+ + G G C+ D C D CP LCV Q P
Sbjct: 248 --SVSPKGQAQCHCPENYHGDGMV-----CLPKDPCTDNLGGCPSNSTLCVY--QKPG-- 296
Query: 249 VSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVC---GFGQ-KCVCN 304
Q C P N + CF C P C R +A C G+ CVC
Sbjct: 297 ----QAFCTCRPGLVSINSNASAGCF------AFCSPFSCDR-SATCQVTADGKTSCVCR 345
Query: 305 TGWTGNGTVC 314
G+G C
Sbjct: 346 ESEVGDGRAC 355
Score = 45.2 bits (102), Expect = 0.001
Identities = 45/168 (26%), Positives = 60/168 (35%), Gaps = 24/168 (14%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGN 83
C G C+ CPG +S PC R C D G QC C SGF G
Sbjct: 1959 CCPGHYGSECQACPGGPSS------------PC-SDRGVCMDGMSGSGQC-LCRSGFAGT 2004
Query: 84 GVE-----CYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPCGR 138
E + C+A C C+E G C G+ G +C+ + Q C
Sbjct: 2005 ACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGP--RCEVQLELQPVC-- 2060
Query: 139 ERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDEC-DLIRPCDDLVSC 185
C P++ C GY+ +G C D C D C + +C
Sbjct: 2061 TPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANC 2108
Score = 43.6 bits (98), Expect = 0.003
Identities = 32/110 (29%), Positives = 44/110 (40%), Gaps = 8/110 (7%)
Query: 24 CVDTDQGFRCERCPGSQTSDGQTCRTA--CSANPCFGGRVP--CQDLPDGRYQCGKCPSG 79
CV G C + DG+ C C + G C + G+ +C C G
Sbjct: 879 CVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDVRGGCHTDALCSYVGPGQSRC-TCKLG 937
Query: 80 FHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCGSCPTGYVGDGRQC 126
F G+G +C I CRA C +C G + +CP G+ GDG C
Sbjct: 938 FAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDGFSC 987
Score = 36.7 bits (81), Expect = 0.33
Identities = 30/104 (28%), Positives = 37/104 (35%), Gaps = 10/104 (9%)
Query: 30 GFRCERCPGSQTSDGQTCRTACSANPCFGG---RVPCQDLPDGRYQCGKCPSGFHGNGVE 86
G CE C DG+ C A GG C + G C + G+G
Sbjct: 2073 GNSCE-CSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQV--GTMVTCTCLPDYEGDGWS 2129
Query: 87 CY-RISC---RANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQC 126
C R C C + +C T + C GYVGDG QC
Sbjct: 2130 CRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQC 2173
Score = 35.5 bits (78), Expect = 0.75
Identities = 60/251 (23%), Positives = 78/251 (31%), Gaps = 46/251 (18%)
Query: 22 ERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH 81
E+CV+ + FRC + G Q D T R +C F C + Q C GF
Sbjct: 1270 EKCVNCTRRFRCTQ--GFQLQD--TPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCCPGFF 1325
Query: 82 GN----------GVECYRISCRANTCFQG-VSCEETQYGPKCGSCPTGYVGDGRQCQHVC 130
G GV C+ G C E +G C C G G C VC
Sbjct: 1326 GTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPN--CTGVC 1383
Query: 131 DAQKPCGRERRCMPKSTSPYYECEG-CPSGYQWNGYTC---VDMDECDLIRPCDDLVSCR 186
D C + +G C W G C + +C R CD +C
Sbjct: 1384 D----------CAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCP--RKCDPNANCV 1431
Query: 187 NEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPS 246
+ G+ G G C +VD CA G C C T P
Sbjct: 1432 QDSAGASTCACAA------GYSGNGI-----FCSEVDPCAHGHGGCSPHANC--TKVAPG 1478
Query: 247 NPVSSLQGSYI 257
+ Q Y+
Sbjct: 1479 QRTCTCQDGYM 1489
Score = 33.9 bits (74), Expect = 2.3
Identities = 15/32 (46%), Positives = 19/32 (59%), Gaps = 1/32 (3%)
Query: 293 AVCGFGQKCVCNTGWTGNGTVCGL-DRDLDGH 323
AVC G C C+ G+ G+G VC + D DGH
Sbjct: 2068 AVCRAGNSCECSLGYEGDGRVCTVADLCQDGH 2099
>X81479-1|CAA57232.1| 886|Homo sapiens EMR1 protein.
Length = 886
Score = 54.0 bits (124), Expect = 2e-06
Identities = 72/279 (25%), Positives = 96/279 (34%), Gaps = 36/279 (12%)
Query: 80 FHGNGVECYRIS-CRANT--CFQGVSCEETQYGPKCG-----SCPTGYVG-DGRQCQHVC 130
F GV C I C + C SC+ KC S PTG G+ C
Sbjct: 71 FKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSC 130
Query: 131 DAQKPCGRERRCMPKS----TSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCR 186
C R C S + Y C C G+ TC D++EC R C + +C
Sbjct: 131 TDINECLTSRVCPEHSDCVNSMGSYSCS-CQVGFISRNSTCEDVNECADPRACPEHATCN 189
Query: 187 NEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPS 246
N S G + C D+DEC + CP C NTP
Sbjct: 190 NTVGNYSCFCNPGFESSSGHLSCQG---LKASCEDIDECTE---MCPINSTCTNTP---- 239
Query: 247 NPVSSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTG 306
GSY C C + ++ + F D V+ D CR+ + CG C G
Sbjct: 240 -------GSYFCT-CHPGFAPSSGQLNF-TDQGVECRDIDECRQDPSTCGPNSICTNALG 290
Query: 307 WTGNGTVCGLDRDLDG-HPDEQLPCNEP--RCKKDNCPD 342
G + G + +G D C +CK+D PD
Sbjct: 291 SYSCGCIVGFHPNPEGSQKDGNFSCQRVLFKCKEDVIPD 329
>U94333-1|AAB53110.1| 652|Homo sapiens C1qR(p) protein.
Length = 652
Score = 54.0 bits (124), Expect = 2e-06
Identities = 51/161 (31%), Positives = 71/161 (44%), Gaps = 24/161 (14%)
Query: 28 DQGFRCERCPGSQTSDGQ-TC--RTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH--G 82
D F C PG + D TC R CS++PC GG C P G+ +CP G+
Sbjct: 280 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGG-ATCVLGPHGKNYTCRCPQGYQLDS 338
Query: 83 NGVECYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGYV--GDGR-QCQHVCD---AQKP 135
+ ++C + C+ + C Q C T G +C C GY G G CQ V + + P
Sbjct: 339 SQLDCVDVDECQDSPCAQ--ECVNTPGGFRC-ECWVGYEPGGPGEGACQDVDECALGRSP 395
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQW---NGYTCVDMDEC 173
C + C +T + C C GY +G C D+DEC
Sbjct: 396 CA--QGC--TNTDGSFHC-SCEEGYVLAGEDGTQCQDVDEC 431
Score = 43.2 bits (97), Expect = 0.004
Identities = 56/187 (29%), Positives = 67/187 (35%), Gaps = 30/187 (16%)
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLIRPCDDLVSCRNEE 189
+ PC C+ Y C CP GYQ + CVD+DEC PC C N
Sbjct: 307 SSSPCRGGATCVLGPHGKNYTCR-CPQGYQLDSSQLDCVDVDECQ-DSPCAQ--ECVNTP 362
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPV 249
G G G C DVDECA GR+ C +G C NT +
Sbjct: 363 GGFRCECWVGY---EPGGPGEGA------CQDVDECALGRSPCAQG--CTNT---DGSFH 408
Query: 250 SSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTGW-- 307
S + Y+ G + C P + CD S C FN F C C GW
Sbjct: 409 CSCEEGYVLAGEDGTQCQDVDE-CVGPGGPL--CD-SLC--FNTQGSF--HCGCLPGWVL 460
Query: 308 TGNGTVC 314
NG C
Sbjct: 461 APNGVSC 467
Score = 32.7 bits (71), Expect = 5.3
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 7/63 (11%)
Query: 22 ERCVDTDQGFRCERCPGSQTSDGQTCRTAC-SANPCFGGRVPCQD---LPDGRYQCGKCP 77
+ CV+T GFRCE G + G AC + C GR PC DG + C C
Sbjct: 356 QECVNTPGGFRCECWVGYE--PGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHC-SCE 412
Query: 78 SGF 80
G+
Sbjct: 413 EGY 415
>U77493-1|AAB19224.1| 263|Homo sapiens Notch2 protein.
Length = 263
Score = 54.0 bits (124), Expect = 2e-06
Identities = 44/139 (31%), Positives = 63/139 (45%), Gaps = 17/139 (12%)
Query: 43 DGQTCRT---ACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRANTCFQ 99
DG C C+ + CF G C D + + C CP GF G+ C ++ C
Sbjct: 14 DGVHCENNINECTESSCFNGGT-CVDGINS-FSC-LCPVGFTGSFCLHEINECSSHPCLN 70
Query: 100 GVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--AQKPCGRERRCMPKSTSPYYECEGCP 157
+C + +C SCP GY G+ CQ + + ++ PC + C+ K SP +C CP
Sbjct: 71 DGTCVDGLGTYRC-SCPLGYT--GKNCQTLVNLCSRSPCKNKGTCVQKKASP--QCL-CP 124
Query: 158 SGYQWNGYTC-VDMDECDL 175
SG W G C V CD+
Sbjct: 125 SG--WVGAYCDVPNVSCDI 141
Score = 52.4 bits (120), Expect = 6e-06
Identities = 56/175 (32%), Positives = 70/175 (40%), Gaps = 25/175 (14%)
Query: 24 CVDTDQGFRCERCPGSQTSDG-QTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHG 82
CVD +RC CP T QT CS +PC Q QC CPSG+ G
Sbjct: 74 CVDGLGTYRCS-CPLGYTGKNCQTLVNLCSRSPCKNKGTCVQ--KKASPQC-LCPSGWVG 129
Query: 83 NGVECYRISCRANTCFQGVSCEE-TQYGPKC---GS-----CPTGYVGDGRQCQHVCD-- 131
+ +SC +GV E Q+ C G+ CP GY G C+ D
Sbjct: 130 AYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPVGYTGS--YCEEQLDEC 187
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTC-VDMDECDLIRPCDDLVSC 185
A PC C Y CE C GYQ G C ++DEC +PC + +C
Sbjct: 188 ASNPCQHGATC--SDFIGGYRCE-CVPGYQ--GVNCEYEVDECQ-NQPCQNGGTC 236
Score = 44.8 bits (101), Expect = 0.001
Identities = 34/117 (29%), Positives = 48/117 (41%), Gaps = 11/117 (9%)
Query: 71 YQCGKCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVC 130
Y C KC +GF G E C ++CF G +C + C CP G+ G C H
Sbjct: 5 YTC-KCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSC-LCPVGFTGS--FCLHEI 60
Query: 131 D--AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVDMDECDLIRPCDDLVSC 185
+ + PC + C+ + Y C CP GY G C + PC + +C
Sbjct: 61 NECSSHPCLNDGTCVDGLGT--YRC-SCPLGY--TGKNCQTLVNLCSRSPCKNKGTC 112
Score = 43.2 bits (97), Expect = 0.004
Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 11/102 (10%)
Query: 75 KCPSGFHGNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCD--A 132
+CP G+ G+ E C +N C G +C + G +C C GY G C++ D
Sbjct: 170 QCPVGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRC-ECVPGY--QGVNCEYEVDECQ 226
Query: 133 QKPCGRERRCMPKSTSPYYECEGCPSGYQWNGYTCVD-MDEC 173
+PC C+ +++C CP G + G C + +D+C
Sbjct: 227 NQPCQNGGTCI--DLVNHFKC-SCPPGTR--GLLCEENIDDC 263
Score = 35.9 bits (79), Expect = 0.57
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 21 GERCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQDLPDGRYQCGKCPSGF 80
G C D G+RCE PG Q + + C PC G C DL + ++C CP G
Sbjct: 195 GATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGT-CIDLVN-HFKC-SCPPGT 251
Query: 81 HG 82
G
Sbjct: 252 RG 253
>BC028075-1|AAH28075.1| 652|Homo sapiens CD93 molecule protein.
Length = 652
Score = 54.0 bits (124), Expect = 2e-06
Identities = 51/161 (31%), Positives = 71/161 (44%), Gaps = 24/161 (14%)
Query: 28 DQGFRCERCPGSQTSDGQ-TC--RTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH--G 82
D F C PG + D TC R CS++PC GG C P G+ +CP G+
Sbjct: 280 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGG-ATCVLGPHGKNYTCRCPQGYQLDS 338
Query: 83 NGVECYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGYV--GDGR-QCQHVCD---AQKP 135
+ ++C + C+ + C Q C T G +C C GY G G CQ V + + P
Sbjct: 339 SQLDCVDVDECQDSPCAQ--ECVNTPGGFRC-ECWVGYEPGGPGEGACQDVDECALGRSP 395
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQW---NGYTCVDMDEC 173
C + C +T + C C GY +G C D+DEC
Sbjct: 396 CA--QGC--TNTDGSFHC-SCEEGYVLAGEDGTQCQDVDEC 431
Score = 43.2 bits (97), Expect = 0.004
Identities = 56/187 (29%), Positives = 67/187 (35%), Gaps = 30/187 (16%)
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLIRPCDDLVSCRNEE 189
+ PC C+ Y C CP GYQ + CVD+DEC PC C N
Sbjct: 307 SSSPCRGGATCVLGPHGKNYTCR-CPQGYQLDSSQLDCVDVDECQ-DSPCAQ--ECVNTP 362
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPV 249
G G G C DVDECA GR+ C +G C NT +
Sbjct: 363 GGFRCECWVGY---EPGGPGEGA------CQDVDECALGRSPCAQG--CTNT---DGSFH 408
Query: 250 SSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTGW-- 307
S + Y+ G + C P + CD S C FN F C C GW
Sbjct: 409 CSCEEGYVLAGEDGTQCQDVDE-CVGPGGPL--CD-SLC--FNTQGSF--HCGCLPGWVL 460
Query: 308 TGNGTVC 314
NG C
Sbjct: 461 APNGVSC 467
Score = 32.7 bits (71), Expect = 5.3
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 7/63 (11%)
Query: 22 ERCVDTDQGFRCERCPGSQTSDGQTCRTAC-SANPCFGGRVPCQD---LPDGRYQCGKCP 77
+ CV+T GFRCE G + G AC + C GR PC DG + C C
Sbjct: 356 QECVNTPGGFRCECWVGYE--PGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHC-SCE 412
Query: 78 SGF 80
G+
Sbjct: 413 EGY 415
>AL118508-1|CAC00597.1| 652|Homo sapiens complement component 1, q
subcomponent, receptor 1 protein.
Length = 652
Score = 54.0 bits (124), Expect = 2e-06
Identities = 51/161 (31%), Positives = 71/161 (44%), Gaps = 24/161 (14%)
Query: 28 DQGFRCERCPGSQTSDGQ-TC--RTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH--G 82
D F C PG + D TC R CS++PC GG C P G+ +CP G+
Sbjct: 280 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGG-ATCVLGPHGKNYTCRCPQGYQLDS 338
Query: 83 NGVECYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGYV--GDGR-QCQHVCD---AQKP 135
+ ++C + C+ + C Q C T G +C C GY G G CQ V + + P
Sbjct: 339 SQLDCVDVDECQDSPCAQ--ECVNTPGGFRC-ECWVGYEPGGPGEGACQDVDECALGRSP 395
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQW---NGYTCVDMDEC 173
C + C +T + C C GY +G C D+DEC
Sbjct: 396 CA--QGC--TNTDGSFHC-SCEEGYVLAGEDGTQCQDVDEC 431
Score = 43.2 bits (97), Expect = 0.004
Identities = 56/187 (29%), Positives = 67/187 (35%), Gaps = 30/187 (16%)
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLIRPCDDLVSCRNEE 189
+ PC C+ Y C CP GYQ + CVD+DEC PC C N
Sbjct: 307 SSSPCRGGATCVLGPHGKNYTCR-CPQGYQLDSSQLDCVDVDECQ-DSPCAQ--ECVNTP 362
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPV 249
G G G C DVDECA GR+ C +G C NT +
Sbjct: 363 GGFRCECWVGY---EPGGPGEGA------CQDVDECALGRSPCAQG--CTNT---DGSFH 408
Query: 250 SSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTGW-- 307
S + Y+ G + C P + CD S C FN F C C GW
Sbjct: 409 CSCEEGYVLAGEDGTQCQDVDE-CVGPGGPL--CD-SLC--FNTQGSF--HCGCLPGWVL 460
Query: 308 TGNGTVC 314
NG C
Sbjct: 461 APNGVSC 467
Score = 32.7 bits (71), Expect = 5.3
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 7/63 (11%)
Query: 22 ERCVDTDQGFRCERCPGSQTSDGQTCRTAC-SANPCFGGRVPCQD---LPDGRYQCGKCP 77
+ CV+T GFRCE G + G AC + C GR PC DG + C C
Sbjct: 356 QECVNTPGGFRCECWVGYE--PGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHC-SCE 412
Query: 78 SGF 80
G+
Sbjct: 413 EGY 415
>AB209895-1|BAD93132.1| 671|Homo sapiens complement component 1, q
subcomponent, receptor 1 variant protein.
Length = 671
Score = 54.0 bits (124), Expect = 2e-06
Identities = 51/161 (31%), Positives = 71/161 (44%), Gaps = 24/161 (14%)
Query: 28 DQGFRCERCPGSQTSDGQ-TC--RTACSANPCFGGRVPCQDLPDGRYQCGKCPSGFH--G 82
D F C PG + D TC R CS++PC GG C P G+ +CP G+
Sbjct: 299 DGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGG-ATCVLGPHGKNYTCRCPQGYQLDS 357
Query: 83 NGVECYRI-SCRANTCFQGVSCEETQYGPKCGSCPTGYV--GDGR-QCQHVCD---AQKP 135
+ ++C + C+ + C Q C T G +C C GY G G CQ V + + P
Sbjct: 358 SQLDCVDVDECQDSPCAQ--ECVNTPGGFRC-ECWVGYEPGGPGEGACQDVDECALGRSP 414
Query: 136 CGRERRCMPKSTSPYYECEGCPSGYQW---NGYTCVDMDEC 173
C + C +T + C C GY +G C D+DEC
Sbjct: 415 CA--QGC--TNTDGSFHC-SCEEGYVLAGEDGTQCQDVDEC 450
Score = 43.2 bits (97), Expect = 0.004
Identities = 56/187 (29%), Positives = 67/187 (35%), Gaps = 30/187 (16%)
Query: 132 AQKPCGRERRCMPKSTSPYYECEGCPSGYQWNG--YTCVDMDECDLIRPCDDLVSCRNEE 189
+ PC C+ Y C CP GYQ + CVD+DEC PC C N
Sbjct: 326 SSSPCRGGATCVLGPHGKNYTCR-CPQGYQLDSSQLDCVDVDECQ-DSPCAQ--ECVNTP 381
Query: 190 XXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPV 249
G G G C DVDECA GR+ C +G C NT +
Sbjct: 382 GGFRCECWVGY---EPGGPGEGA------CQDVDECALGRSPCAQG--CTNT---DGSFH 427
Query: 250 SSLQGSYICVPCGGHYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTGW-- 307
S + Y+ G + C P + CD S C FN F C C GW
Sbjct: 428 CSCEEGYVLAGEDGTQCQDVDE-CVGPGGPL--CD-SLC--FNTQGSF--HCGCLPGWVL 479
Query: 308 TGNGTVC 314
NG C
Sbjct: 480 APNGVSC 486
Score = 32.7 bits (71), Expect = 5.3
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 7/63 (11%)
Query: 22 ERCVDTDQGFRCERCPGSQTSDGQTCRTAC-SANPCFGGRVPCQD---LPDGRYQCGKCP 77
+ CV+T GFRCE G + G AC + C GR PC DG + C C
Sbjct: 375 QECVNTPGGFRCECWVGYE--PGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHC-SCE 431
Query: 78 SGF 80
G+
Sbjct: 432 EGY 434
>BC035608-1|AAH35608.1| 969|Homo sapiens NID2 protein protein.
Length = 969
Score = 53.6 bits (123), Expect = 3e-06
Identities = 42/147 (28%), Positives = 55/147 (37%), Gaps = 15/147 (10%)
Query: 8 DAGSMVTPFKLC-VGERCVDTDQGFRCE-RCPGSQTSDGQTCRTACS-ANPCFGGRVPCQ 64
D T F C C++ +RCE R D TC ANPC G C
Sbjct: 395 DENECATGFHRCGPNSVCINLPGSYRCECRSAYEFADDRHTCILITPPANPCEDGSHTCA 454
Query: 65 DLPDGR--------YQCGKCPSGFHGNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSC 115
R + C C G+ G+G +C + C N C +C T C C
Sbjct: 455 PAGQARCVHHGGSTFSCA-CLPGYAGDGHQCTDVDECSENRCHPAATCYNTPGSFSC-RC 512
Query: 116 PTGYVGDGRQC-QHVCDAQKPCGRERR 141
GY GDG QC + PC +++R
Sbjct: 513 QPGYYGDGFQCIPDSTSSLTPCEQQQR 539
Score = 45.6 bits (103), Expect = 7e-04
Identities = 46/163 (28%), Positives = 67/163 (41%), Gaps = 27/163 (16%)
Query: 95 NTCFQGVS-CEET-QYGPKCG-----SCPTGYVGDGRQC--QHVCDAQ-KPCGRERRCMP 144
N C+ G C+ T + P G C +GY GDGR C ++ C CG C+
Sbjct: 355 NPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCIN 414
Query: 145 KSTSPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDD---LVSCRNEEXXXXXXXXXX 199
S Y CE C S Y++ + +TC+ + PC+D + +
Sbjct: 415 LPGS--YRCE-CRSAYEFADDRHTCILITPP--ANPCEDGSHTCAPAGQARCVHHGGSTF 469
Query: 200 XXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
G+ G G++ C DVDEC++ R C C NTP
Sbjct: 470 SCACLPGYAGDGHQ-----CTDVDECSENR--CHPAATCYNTP 505
Score = 41.1 bits (92), Expect = 0.015
Identities = 40/154 (25%), Positives = 55/154 (35%), Gaps = 25/154 (16%)
Query: 54 NPCFGGRVPCQDLPDGR------YQCGKCPSGFHGNGVECY-RISCRA--NTCFQGVSCE 104
NPC+ G C Y C +C SG+ G+G C C + C C
Sbjct: 355 NPCYDGSHMCDTTARCHPGTGVDYTC-ECASGYQGDGRNCVDENECATGFHRCGPNSVCI 413
Query: 105 ETQYGPKCGSCPTGY--VGDGRQCQHVCDAQKPC---------GRERRCMPKSTSPYYEC 153
+C C + Y D C + PC + RC+ S + C
Sbjct: 414 NLPGSYRC-ECRSAYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTF-SC 471
Query: 154 EGCPSGYQWNGYTCVDMDECDLIRPCDDLVSCRN 187
C GY +G+ C D+DEC R C +C N
Sbjct: 472 -ACLPGYAGDGHQCTDVDECSENR-CHPAATCYN 503
Score = 33.9 bits (74), Expect = 2.3
Identities = 28/111 (25%), Positives = 43/111 (38%), Gaps = 9/111 (8%)
Query: 204 SQGWRGTGNERRREHCVDVDECADGRANCPRGRLCVNTPQYPSNPVSSLQGSYICVPCGG 263
+ G++G G +CVD +ECA G C +C+N P + + +Y
Sbjct: 383 ASGYQGDGR-----NCVDENECATGFHRCGPNSVCIN---LPGSYRCECRSAYEFAD-DR 433
Query: 264 HYYVNTTRPCFDPDSLVKRCDPSYCRRFNAVCGFGQKCVCNTGWTGNGTVC 314
H + T P + C P+ R G C C G+ G+G C
Sbjct: 434 HTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQC 484
>AK126775-1|BAC86684.1| 952|Homo sapiens protein ( Homo sapiens
cDNA FLJ44823 fis, clone BRACE3046466, weakly similar
to Crumbs protein homolog 1 precursor. ).
Length = 952
Score = 53.6 bits (123), Expect = 3e-06
Identities = 44/136 (32%), Positives = 56/136 (41%), Gaps = 10/136 (7%)
Query: 6 MGDAGSMVTPFKLCVGE-RCVDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQ 64
+G G+ V C+ + C D F C PG + + C + PC GR C
Sbjct: 720 LGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR--CH 777
Query: 65 DLPDGRYQCGKCPSGFHGNGVECYRIS--CRAN-TCFQGVSCEETQYGPKCGSCPTGYVG 121
PDGR++C +CP GF G S C N TC G CE C SC G G
Sbjct: 778 THPDGRFEC-RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGRSPAANC-SCLEGLAG 835
Query: 122 DGRQCQHV-CDAQKPC 136
Q + C+A PC
Sbjct: 836 QRCQVPTLPCEA-NPC 850
Score = 33.1 bits (72), Expect = 4.0
Identities = 28/90 (31%), Positives = 33/90 (36%), Gaps = 9/90 (10%)
Query: 19 CVGERC-VDTDQGFRCERCPGSQTSDGQTCRTACSANPCFGGRVPCQD-LP-DGRYQCGK 75
C RC D F C RCP G CR + C V C D P +GR
Sbjct: 771 CARGRCHTHPDGRFEC-RCPPG--FGGPRCRLPVPSKEC-SLNVTCLDGSPCEGRSPAAN 826
Query: 76 CP--SGFHGNGVECYRISCRANTCFQGVSC 103
C G G + + C AN C G +C
Sbjct: 827 CSCLEGLAGQRCQVPTLPCEANPCLNGGTC 856
>BC111690-1|AAI11691.1| 807|Homo sapiens SCUBE2 protein protein.
Length = 807
Score = 52.8 bits (121), Expect = 5e-06
Identities = 45/156 (28%), Positives = 71/156 (45%), Gaps = 24/156 (15%)
Query: 91 SCRANTCFQGVSCEETQYGPKCGSCPTGYVG--DGRQCQHVCDAQ-KPCGRERRCMPKST 147
+C N +C++T G C SCP G+ DG+ C+ + + Q + G + C K+
Sbjct: 285 TCAVNNGGCDRTCKDTSTGVHC-SCPVGFTLQLDGKTCKDIDECQTRNGGCDHFC--KNI 341
Query: 148 SPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQ 205
++C GC G++ + +C D+DEC L R CD SC N ++
Sbjct: 342 VGSFDC-GCKKGFKLLTDEKSCQDVDECSLDRTCDH--SCINHP-------GTFACACNR 391
Query: 206 GWRGTGNERRREHCVDVDECADGRANCPRGRLCVNT 241
G+ G HC D +EC+ C ++CVNT
Sbjct: 392 GYTLYG----FTHCGDTNECSINNGGCQ--QVCVNT 421
Score = 46.4 bits (105), Expect = 4e-04
Identities = 27/81 (33%), Positives = 39/81 (48%), Gaps = 8/81 (9%)
Query: 97 CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKPCGRERRCMPKSTSPYYECE 154
C C+ T KC SC GY G+GRQC+ + C + G C+ + Y C
Sbjct: 56 CHADALCQNTPTSYKC-SCKPGYQGEGRQCEDIDECGNELNGGCVHDCL--NIPGNYRCT 112
Query: 155 GCPSGYQ--WNGYTCVDMDEC 173
C G+ +G+ C+D+DEC
Sbjct: 113 -CFDGFMLAHDGHNCLDVDEC 132
Score = 33.9 bits (74), Expect = 2.3
Identities = 57/213 (26%), Positives = 79/213 (37%), Gaps = 51/213 (23%)
Query: 63 CQDLPDGRYQCGKCPSGFH--GNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYV 120
C++ P G C +C GF N +C ++C SC++T GP+C SC Y
Sbjct: 188 CKEAPRGSVAC-ECRPGFELAKNQRDCI-LTCNHGNGGCQHSCDDTADGPEC-SCHPQYK 244
Query: 121 --GDGRQC---------------QHVCDAQKPCGRE---RRCMPKSTSPYYECE------ 154
DGR C V D K R C + C+
Sbjct: 245 MHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTGV 304
Query: 155 --GCPSGY--QWNGYTCVDMDECDLIR-PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRG 209
CP G+ Q +G TC D+DEC CD C+N +G++
Sbjct: 305 HCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHF--CKN-------IVGSFDCGCKKGFKL 355
Query: 210 TGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
+E+ C DVDEC+ R C C+N P
Sbjct: 356 LTDEK---SCQDVDECSLDR-TCDHS--CINHP 382
Score = 32.3 bits (70), Expect = 7.0
Identities = 13/22 (59%), Positives = 14/22 (63%)
Query: 221 DVDECADGRANCPRGRLCVNTP 242
DVDECA G +C LC NTP
Sbjct: 45 DVDECAQGLDDCHADALCQNTP 66
>BC035784-1|AAH35784.1| 439|Homo sapiens hypothetical protein
FLJ37440 protein.
Length = 439
Score = 52.8 bits (121), Expect = 5e-06
Identities = 49/170 (28%), Positives = 70/170 (41%), Gaps = 25/170 (14%)
Query: 38 GSQTSDGQTCR--TACSANPCFGGRVPCQDLPDGRYQCGKCPSGFHGNGVECYRISCRAN 95
G+ T + CR + CS+ PC G + + +Y+C CP G GN + +
Sbjct: 125 GTWTGEQPHCRGISECSSQPCQNGGTCVEGV--NQYRC-ICPPGRTGNRCQHQAQTAAPE 181
Query: 96 TCFQGVS-------CEETQYGPKCGSCPTGYVGDGRQCQHVCDAQKPC------GRERRC 142
G S C + + C SC G+ G VC C GR R C
Sbjct: 182 GSVAGDSAFSRAPRCAQVERAQHC-SCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLC 240
Query: 143 MPK--STSPYYECEGCPSGYQW--NGYTCVDMDECDLIRP-CDDLVSCRN 187
M +T Y C CP GY+ +G +C D+DEC ++P C +C N
Sbjct: 241 MHACVNTPGSYRCT-CPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCIN 289
Score = 48.0 bits (109), Expect = 1e-04
Identities = 50/184 (27%), Positives = 72/184 (39%), Gaps = 35/184 (19%)
Query: 77 PSG-FHGNGVECYRIS-CRANTCFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHVCDAQK 134
P+G + G C IS C + C G +C E +C CP G G+ +CQH
Sbjct: 123 PNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRC-ICPPGRTGN--RCQHQAQTAA 179
Query: 135 PCG---------RERRCMPKSTSPYYECEGCPSGYQWNGYT----CVDMDECDLI----R 177
P G R RC + + CE +G+ +G C D++EC+L R
Sbjct: 180 PEGSVAGDSAFSRAPRCAQVERAQHCSCE---AGFHLSGAAGDSVCQDVNECELYGQEGR 236
Query: 178 PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRGTGNERRREHCVDVDECADGRANCPRGRL 237
P + +C N + G + C DVDEC + CP+G
Sbjct: 237 PRLCMHACVNTPGSYRCTCPGGYRTLADG----------KSCEDVDECVGLQPVCPQGTT 286
Query: 238 CVNT 241
C+NT
Sbjct: 287 CINT 290
>AK131552-1|BAD18686.1| 682|Homo sapiens protein ( Homo sapiens
cDNA FLJ16792 fis, clone TBAES2007379, moderately
similar to Homo sapiens signal peptide, CUB domain,
EGF-like 2 (SCUBE2). ).
Length = 682
Score = 52.8 bits (121), Expect = 5e-06
Identities = 45/156 (28%), Positives = 71/156 (45%), Gaps = 24/156 (15%)
Query: 91 SCRANTCFQGVSCEETQYGPKCGSCPTGYVG--DGRQCQHVCDAQ-KPCGRERRCMPKST 147
+C N +C++T G C SCP G+ DG+ C+ + + Q + G + C K+
Sbjct: 285 TCAVNNGGCDRTCKDTSTGVHC-SCPVGFTLQLDGKTCKDIDECQTRNGGCDHFC--KNI 341
Query: 148 SPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQ 205
++C GC G++ + +C D+DEC L R CD SC N ++
Sbjct: 342 VGSFDC-GCKKGFKLLTDEKSCQDVDECSLDRTCDH--SCINHP-------GTFACACNR 391
Query: 206 GWRGTGNERRREHCVDVDECADGRANCPRGRLCVNT 241
G+ G HC D +EC+ C ++CVNT
Sbjct: 392 GYTLYG----FTHCGDTNECSINNGGCQ--QVCVNT 421
Score = 46.4 bits (105), Expect = 4e-04
Identities = 27/81 (33%), Positives = 39/81 (48%), Gaps = 8/81 (9%)
Query: 97 CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKPCGRERRCMPKSTSPYYECE 154
C C+ T KC SC GY G+GRQC+ + C + G C+ + Y C
Sbjct: 56 CHADALCQNTPTSYKC-SCKPGYQGEGRQCEDIDECGNELNGGCVHDCL--NIPGNYRCT 112
Query: 155 GCPSGYQ--WNGYTCVDMDEC 173
C G+ +G+ C+D+DEC
Sbjct: 113 -CFDGFMLAHDGHNCLDVDEC 132
Score = 36.7 bits (81), Expect = 0.33
Identities = 61/216 (28%), Positives = 82/216 (37%), Gaps = 57/216 (26%)
Query: 63 CQDLPDGRYQCGKCPSGFH--GNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYV 120
C++ P G C +C GF N +C ++C SC++T GP+C SC Y
Sbjct: 188 CKEAPRGSVAC-ECRPGFELAKNQRDCI-LTCNHGNGGCQHSCDDTADGPEC-SCHPQYK 244
Query: 121 --GDGRQC---------------QHVCDAQKPCGRE--------------RRCMPKSTSP 149
DGR C V D K R+ R C K TS
Sbjct: 245 MHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRQLLMETCAVNNGGCDRTC--KDTST 302
Query: 150 YYECEGCPSGY--QWNGYTCVDMDECDLIR-PCDDLVSCRNEEXXXXXXXXXXXXXXSQG 206
C CP G+ Q +G TC D+DEC CD C+N +G
Sbjct: 303 GVHC-SCPVGFTLQLDGKTCKDIDECQTRNGGCDHF--CKN-------IVGSFDCGCKKG 352
Query: 207 WRGTGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
++ +E+ C DVDEC+ R C C+N P
Sbjct: 353 FKLLTDEK---SCQDVDECSLDR-TCDHS--CINHP 382
Score = 32.3 bits (70), Expect = 7.0
Identities = 13/22 (59%), Positives = 14/22 (63%)
Query: 221 DVDECADGRANCPRGRLCVNTP 242
DVDECA G +C LC NTP
Sbjct: 45 DVDECAQGLDDCHADALCQNTP 66
>AK123039-1|BAC85521.1| 971|Homo sapiens protein ( Homo sapiens
cDNA FLJ41044 fis, clone NT2RP7000466, highly similar
to Mus musculus CUB domain and EGF-like repeat
containing 1 (Cegf1). ).
Length = 971
Score = 52.8 bits (121), Expect = 5e-06
Identities = 45/156 (28%), Positives = 71/156 (45%), Gaps = 24/156 (15%)
Query: 91 SCRANTCFQGVSCEETQYGPKCGSCPTGYVG--DGRQCQHVCDAQ-KPCGRERRCMPKST 147
+C N +C++T G C SCP G+ DG+ C+ + + Q + G + C K+
Sbjct: 285 TCAVNNGGCDRTCKDTSTGVHC-SCPVGFTLQLDGKTCKDIDECQTRNGGCDHFC--KNI 341
Query: 148 SPYYECEGCPSGYQW--NGYTCVDMDECDLIRPCDDLVSCRNEEXXXXXXXXXXXXXXSQ 205
++C GC G++ + +C D+DEC L R CD SC N ++
Sbjct: 342 VGSFDC-GCKKGFKLLTDEKSCQDVDECSLDRTCDH--SCINHP-------GTFACACNR 391
Query: 206 GWRGTGNERRREHCVDVDECADGRANCPRGRLCVNT 241
G+ G HC D +EC+ C ++CVNT
Sbjct: 392 GYTLYG----FTHCGDTNECSINNGGCQ--QVCVNT 421
Score = 46.4 bits (105), Expect = 4e-04
Identities = 27/81 (33%), Positives = 39/81 (48%), Gaps = 8/81 (9%)
Query: 97 CFQGVSCEETQYGPKCGSCPTGYVGDGRQCQHV--CDAQKPCGRERRCMPKSTSPYYECE 154
C C+ T KC SC GY G+GRQC+ + C + G C+ + Y C
Sbjct: 56 CHADALCQNTPTSYKC-SCKPGYQGEGRQCEDIDECGNELNGGCVHDCL--NIPGNYRCT 112
Query: 155 GCPSGYQ--WNGYTCVDMDEC 173
C G+ +G+ C+D+DEC
Sbjct: 113 -CFDGFMLAHDGHNCLDVDEC 132
Score = 33.9 bits (74), Expect = 2.3
Identities = 57/213 (26%), Positives = 79/213 (37%), Gaps = 51/213 (23%)
Query: 63 CQDLPDGRYQCGKCPSGFH--GNGVECYRISCRANTCFQGVSCEETQYGPKCGSCPTGYV 120
C++ P G C +C GF N +C ++C SC++T GP+C SC Y
Sbjct: 188 CKEAPRGSVAC-ECRPGFELAKNQRDCI-LTCNHGNGGCQHSCDDTADGPEC-SCHPQYK 244
Query: 121 --GDGRQC---------------QHVCDAQKPCGRE---RRCMPKSTSPYYECE------ 154
DGR C V D K R C + C+
Sbjct: 245 MHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTGV 304
Query: 155 --GCPSGY--QWNGYTCVDMDECDLIR-PCDDLVSCRNEEXXXXXXXXXXXXXXSQGWRG 209
CP G+ Q +G TC D+DEC CD C+N +G++
Sbjct: 305 HCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHF--CKN-------IVGSFDCGCKKGFKL 355
Query: 210 TGNERRREHCVDVDECADGRANCPRGRLCVNTP 242
+E+ C DVDEC+ R C C+N P
Sbjct: 356 LTDEK---SCQDVDECSLDR-TCDHS--CINHP 382
Score = 32.3 bits (70), Expect = 7.0
Identities = 13/22 (59%), Positives = 14/22 (63%)
Query: 221 DVDECADGRANCPRGRLCVNTP 242
DVDECA G +C LC NTP
Sbjct: 45 DVDECAQGLDDCHADALCQNTP 66
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.139 0.470
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 126,596,127
Number of Sequences: 224733
Number of extensions: 5854273
Number of successful extensions: 20638
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 218
Number of HSP's successfully gapped in prelim test: 509
Number of HSP's that attempted gapping in prelim test: 13211
Number of HSP's gapped (non-prelim): 4909
length of query: 804
length of database: 73,234,838
effective HSP length: 96
effective length of query: 708
effective length of database: 51,660,470
effective search space: 36575612760
effective search space used: 36575612760
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 69 (31.9 bits)
- SilkBase 1999-2023 -