Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001755-TA|BGIBMGA001755-PA|IPR007123|Gelsolin region,
IPR007122|Gelsolin
(353 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X04412-1|CAA28000.1| 782|Homo sapiens plasma gelsolin protein. 189 1e-47
BC026033-1|AAH26033.1| 782|Homo sapiens gelsolin (amyloidosis, ... 189 1e-47
AL513122-3|CAI14413.1| 782|Homo sapiens gelsolin (amyloidosis, ... 189 1e-47
AL513122-6|CAM20459.1| 731|Homo sapiens gelsolin (amyloidosis, ... 188 3e-47
AK075123-1|BAC11416.1| 715|Homo sapiens protein ( Homo sapiens ... 176 8e-44
AF276507-1|AAK60494.1| 715|Homo sapiens scinderin protein. 176 8e-44
AC005281-1|AAD15423.1| 527|Homo sapiens WUGSC:H_DJ0722F20.1 pro... 176 8e-44
AB067492-1|BAB67798.1| 626|Homo sapiens KIAA1905 protein protein. 176 8e-44
BC021090-1|AAH21090.1| 715|Homo sapiens SCIN protein protein. 176 1e-43
BC111730-1|AAI11731.1| 812|Homo sapiens AVIL protein protein. 175 3e-43
AF041449-1|AAC25051.1| 819|Homo sapiens advillin protein. 175 3e-43
AL513122-5|CAI14415.1| 260|Homo sapiens gelsolin (amyloidosis, ... 169 1e-41
AL513122-4|CAI14414.1| 228|Homo sapiens gelsolin (amyloidosis, ... 169 1e-41
X12901-1|CAA31386.1| 827|Homo sapiens protein ( Human mRNA for ... 154 4e-37
BC017303-1|AAH17303.1| 421|Homo sapiens VIL1 protein protein. 154 4e-37
AK223398-1|BAD97118.1| 827|Homo sapiens villin 1 variant protein. 154 4e-37
M94345-1|AAA59570.1| 348|Homo sapiens macrophage capping protei... 141 3e-33
BC014549-1|AAH14549.1| 348|Homo sapiens capping protein (actin ... 141 3e-33
BC000728-1|AAH00728.1| 348|Homo sapiens capping protein (actin ... 141 3e-33
AC062037-3|AAY24128.1| 348|Homo sapiens unknown protein. 141 4e-33
AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va... 111 4e-24
U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. 110 6e-24
U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot... 110 6e-24
BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D... 110 6e-24
U12026-1|AAA92670.1| 172|Homo sapiens Cap-G protein. 105 3e-22
AL513122-7|CAI14416.1| 485|Homo sapiens gelsolin (amyloidosis, ... 78 5e-14
BC017491-1|AAH17491.1| 285|Homo sapiens Similar to gelsolin (am... 70 1e-11
AK075198-1|BAC11465.1| 396|Homo sapiens protein ( Homo sapiens ... 65 4e-10
AK027778-1|BAB55361.1| 468|Homo sapiens protein ( Homo sapiens ... 65 4e-10
D88154-1|BAA21668.1| 686|Homo sapiens villin-like protein protein. 58 5e-08
BC004300-1|AAH04300.1| 672|Homo sapiens VILL protein protein. 58 5e-08
BC000243-1|AAH00243.1| 686|Homo sapiens VILL protein protein. 58 5e-08
AL160060-2|CAH71301.1| 1788|Homo sapiens supervillin protein. 50 1e-05
AL160060-1|CAH71300.1| 2214|Homo sapiens supervillin protein. 50 1e-05
AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein. 50 1e-05
AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein. 50 1e-05
AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein. 50 1e-05
AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein. 50 1e-05
AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein. 50 1e-05
AL590005-3|CAI14988.1| 5457|Homo sapiens dystonin protein. 31 6.1
AL590005-2|CAI14989.1| 7543|Homo sapiens dystonin protein. 31 6.1
AL512448-3|CAI16610.1| 5144|Homo sapiens dystonin protein. 31 6.1
AL512448-2|CAI16608.1| 5457|Homo sapiens dystonin protein. 31 6.1
AL512448-1|CAI16609.1| 7543|Homo sapiens dystonin protein. 31 6.1
AL512422-3|CAI14342.1| 5457|Homo sapiens dystonin protein. 31 6.1
AL512422-2|CAI14341.1| 7543|Homo sapiens dystonin protein. 31 6.1
AL137008-4|CAI20332.1| 5144|Homo sapiens dystonin protein. 31 6.1
AL137008-3|CAI20331.1| 5457|Homo sapiens dystonin protein. 31 6.1
AL137008-2|CAI20330.1| 7543|Homo sapiens dystonin protein. 31 6.1
AL096710-4|CAI22045.1| 5144|Homo sapiens dystonin protein. 31 6.1
AL096710-3|CAI22044.1| 7543|Homo sapiens dystonin protein. 31 6.1
AL096710-2|CAI22043.1| 5457|Homo sapiens dystonin protein. 31 6.1
AK094883-1|BAC04449.1| 775|Homo sapiens protein ( Homo sapiens ... 31 6.1
AF400226-1|AAL62061.1| 5171|Homo sapiens bullous pemphigoid anti... 31 6.1
AL513122-9|CAI14417.1| 207|Homo sapiens gelsolin (amyloidosis, ... 31 8.1
>X04412-1|CAA28000.1| 782|Homo sapiens plasma gelsolin protein.
Length = 782
Score = 189 bits (461), Expect = 1e-47
Identities = 129/384 (33%), Positives = 189/384 (49%), Gaps = 45/384 (11%)
Query: 6 SCLLFVLLGSVWARTATKPQEISG-PITSLSDKNARDKAKVHPAFANVGRTAGVQIWRIQ 64
S L L V A TA++ +G P + + HP F G+ G+QIWR++
Sbjct: 15 SLALCALSLPVRAATASRGASQAGAPQGRVPEARPNSMVVEHPEFLKAGKEPGLQIWRVE 74
Query: 65 T------------------------TSDNRN-NLSWDIHYWIGRESTQDESGAAAILTVG 99
T RN NL +D+HYW+G E +QDESGAAAI TV
Sbjct: 75 KFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQ 134
Query: 100 LDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKG 159
LDD G AVQHRE G ESA FL YF++ L Y +GG SGF HVV N +R+FQVKG
Sbjct: 135 LDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKG 194
Query: 160 KRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHG 219
+R VR +V S N GD F+LDL N+I+ + G + E+LKA + +RD + G
Sbjct: 195 RRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSG 254
Query: 220 RGRVDIVDKYSSDVDVQKFF---TALGSGVKDLVPDESTGGDDQEFER--NEASNVILSE 274
R RV + ++ + + + AL +G +D +++ + + N A + +S
Sbjct: 255 RARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSL 314
Query: 275 VSD----ATGKIK-----VTPLSKP-----FKQENLSPQEKSQAMTKAQELLNAKNYPSW 320
V+D A G +K + K +K + + +E+ A+ A + + +YP
Sbjct: 315 VADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQ 374
Query: 321 VQVTRVLQNTEPAAFKQYFFTWRD 344
QV+ + + E FKQ+F WRD
Sbjct: 375 TQVSVLPEGGETPLFKQFFKNWRD 398
Score = 77.8 bits (183), Expect = 5e-14
Identities = 51/142 (35%), Positives = 69/142 (48%), Gaps = 6/142 (4%)
Query: 77 IHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYF-QTPLNYLEG 135
I+ W G +STQDE A+AILT LD++ GG VQ R G E A +S F P+ +G
Sbjct: 490 IYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKG 549
Query: 136 GNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVD--PQIASMNKGDVFVLDLDNDIYVFV 193
G A A R+FQV+ R V+ P+ ++N D FVL + Y++V
Sbjct: 550 GTSREGGQ---TAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWV 606
Query: 194 GEKAKNVEKLKAISFANQVRDQ 215
G A EK A +R Q
Sbjct: 607 GTGASEAEKTGAQELLRVLRAQ 628
Score = 30.7 bits (66), Expect = 8.1
Identities = 14/44 (31%), Positives = 27/44 (61%)
Query: 179 DVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGR 222
DV +LD + ++V+VG+ ++ EK +A++ A + + D R R
Sbjct: 697 DVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDR 740
>BC026033-1|AAH26033.1| 782|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 782
Score = 189 bits (461), Expect = 1e-47
Identities = 129/384 (33%), Positives = 189/384 (49%), Gaps = 45/384 (11%)
Query: 6 SCLLFVLLGSVWARTATKPQEISG-PITSLSDKNARDKAKVHPAFANVGRTAGVQIWRIQ 64
S L L V A TA++ +G P + + HP F G+ G+QIWR++
Sbjct: 15 SLALCALSLPVRAATASRGASQAGAPQGRVPEARPNSMVVEHPEFLKAGKEPGLQIWRVE 74
Query: 65 T------------------------TSDNRN-NLSWDIHYWIGRESTQDESGAAAILTVG 99
T RN NL +D+HYW+G E +QDESGAAAI TV
Sbjct: 75 KFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQ 134
Query: 100 LDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKG 159
LDD G AVQHRE G ESA FL YF++ L Y +GG SGF HVV N +R+FQVKG
Sbjct: 135 LDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKG 194
Query: 160 KRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHG 219
+R VR +V S N GD F+LDL N+I+ + G + E+LKA + +RD + G
Sbjct: 195 RRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSG 254
Query: 220 RGRVDIVDKYSSDVDVQKFF---TALGSGVKDLVPDESTGGDDQEFER--NEASNVILSE 274
R RV + ++ + + + AL +G +D +++ + + N A + +S
Sbjct: 255 RARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSL 314
Query: 275 VSD----ATGKIK-----VTPLSKP-----FKQENLSPQEKSQAMTKAQELLNAKNYPSW 320
V+D A G +K + K +K + + +E+ A+ A + + +YP
Sbjct: 315 VADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQ 374
Query: 321 VQVTRVLQNTEPAAFKQYFFTWRD 344
QV+ + + E FKQ+F WRD
Sbjct: 375 TQVSVLPEGGETPLFKQFFKNWRD 398
Score = 77.8 bits (183), Expect = 5e-14
Identities = 51/142 (35%), Positives = 69/142 (48%), Gaps = 6/142 (4%)
Query: 77 IHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYF-QTPLNYLEG 135
I+ W G +STQDE A+AILT LD++ GG VQ R G E A +S F P+ +G
Sbjct: 490 IYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKG 549
Query: 136 GNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVD--PQIASMNKGDVFVLDLDNDIYVFV 193
G A A R+FQV+ R V+ P+ ++N D FVL + Y++V
Sbjct: 550 GTSREGGQ---TAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWV 606
Query: 194 GEKAKNVEKLKAISFANQVRDQ 215
G A EK A +R Q
Sbjct: 607 GTGASEAEKTGAQELLRVLRAQ 628
Score = 30.7 bits (66), Expect = 8.1
Identities = 14/44 (31%), Positives = 27/44 (61%)
Query: 179 DVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGR 222
DV +LD + ++V+VG+ ++ EK +A++ A + + D R R
Sbjct: 697 DVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDR 740
>AL513122-3|CAI14413.1| 782|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 782
Score = 189 bits (461), Expect = 1e-47
Identities = 129/384 (33%), Positives = 189/384 (49%), Gaps = 45/384 (11%)
Query: 6 SCLLFVLLGSVWARTATKPQEISG-PITSLSDKNARDKAKVHPAFANVGRTAGVQIWRIQ 64
S L L V A TA++ +G P + + HP F G+ G+QIWR++
Sbjct: 15 SLALCALSLPVRAATASRGASQAGAPQGRVPEARPNSMVVEHPEFLKAGKEPGLQIWRVE 74
Query: 65 T------------------------TSDNRN-NLSWDIHYWIGRESTQDESGAAAILTVG 99
T RN NL +D+HYW+G E +QDESGAAAI TV
Sbjct: 75 KFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQ 134
Query: 100 LDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKG 159
LDD G AVQHRE G ESA FL YF++ L Y +GG SGF HVV N +R+FQVKG
Sbjct: 135 LDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKG 194
Query: 160 KRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHG 219
+R VR +V S N GD F+LDL N+I+ + G + E+LKA + +RD + G
Sbjct: 195 RRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSG 254
Query: 220 RGRVDIVDKYSSDVDVQKFF---TALGSGVKDLVPDESTGGDDQEFER--NEASNVILSE 274
R RV + ++ + + + AL +G +D +++ + + N A + +S
Sbjct: 255 RARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSL 314
Query: 275 VSD----ATGKIK-----VTPLSKP-----FKQENLSPQEKSQAMTKAQELLNAKNYPSW 320
V+D A G +K + K +K + + +E+ A+ A + + +YP
Sbjct: 315 VADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQ 374
Query: 321 VQVTRVLQNTEPAAFKQYFFTWRD 344
QV+ + + E FKQ+F WRD
Sbjct: 375 TQVSVLPEGGETPLFKQFFKNWRD 398
Score = 77.8 bits (183), Expect = 5e-14
Identities = 51/142 (35%), Positives = 69/142 (48%), Gaps = 6/142 (4%)
Query: 77 IHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYF-QTPLNYLEG 135
I+ W G +STQDE A+AILT LD++ GG VQ R G E A +S F P+ +G
Sbjct: 490 IYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKG 549
Query: 136 GNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVD--PQIASMNKGDVFVLDLDNDIYVFV 193
G A A R+FQV+ R V+ P+ ++N D FVL + Y++V
Sbjct: 550 GTSREGGQ---TAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWV 606
Query: 194 GEKAKNVEKLKAISFANQVRDQ 215
G A EK A +R Q
Sbjct: 607 GTGASEAEKTGAQELLRVLRAQ 628
Score = 30.7 bits (66), Expect = 8.1
Identities = 14/44 (31%), Positives = 27/44 (61%)
Query: 179 DVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGR 222
DV +LD + ++V+VG+ ++ EK +A++ A + + D R R
Sbjct: 697 DVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDR 740
>AL513122-6|CAM20459.1| 731|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 731
Score = 188 bits (458), Expect = 3e-47
Identities = 109/301 (36%), Positives = 162/301 (53%), Gaps = 19/301 (6%)
Query: 63 IQTTSDNRNNLSWDIHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALF 122
++T NL +D+HYW+G E +QDESGAAAI TV LDD G AVQHRE G ESA F
Sbjct: 47 LKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATF 106
Query: 123 LSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFV 182
L YF++ L Y +GG SGF HVV N +R+FQVKG+R VR +V S N GD F+
Sbjct: 107 LGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFI 166
Query: 183 LDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFF--- 239
LDL N+I+ + G + E+LKA + +RD + GR RV + ++ + + +
Sbjct: 167 LDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPK 226
Query: 240 TALGSGVKDLVPDESTGGDDQEFER--NEASNVILSEVSD----ATGKIK-----VTPLS 288
AL +G +D +++ + + N A + +S V+D A G +K +
Sbjct: 227 PALPAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHG 286
Query: 289 KP-----FKQENLSPQEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWR 343
K +K + + +E+ A+ A + + +YP QV+ + + E FKQ+F WR
Sbjct: 287 KDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWR 346
Query: 344 D 344
D
Sbjct: 347 D 347
Score = 77.8 bits (183), Expect = 5e-14
Identities = 51/142 (35%), Positives = 69/142 (48%), Gaps = 6/142 (4%)
Query: 77 IHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYF-QTPLNYLEG 135
I+ W G +STQDE A+AILT LD++ GG VQ R G E A +S F P+ +G
Sbjct: 439 IYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKG 498
Query: 136 GNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVD--PQIASMNKGDVFVLDLDNDIYVFV 193
G A A R+FQV+ R V+ P+ ++N D FVL + Y++V
Sbjct: 499 GTSREGGQ---TAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWV 555
Query: 194 GEKAKNVEKLKAISFANQVRDQ 215
G A EK A +R Q
Sbjct: 556 GTGASEAEKTGAQELLRVLRAQ 577
Score = 30.7 bits (66), Expect = 8.1
Identities = 14/44 (31%), Positives = 27/44 (61%)
Query: 179 DVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGR 222
DV +LD + ++V+VG+ ++ EK +A++ A + + D R R
Sbjct: 646 DVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDR 689
>AK075123-1|BAC11416.1| 715|Homo sapiens protein ( Homo sapiens
cDNA FLJ90642 fis, clone PLACE1004078, highly similar to
Bovine mRNA for adseverin. ).
Length = 715
Score = 176 bits (429), Expect = 8e-44
Identities = 120/351 (34%), Positives = 175/351 (49%), Gaps = 60/351 (17%)
Query: 46 HPAFANVGRTAGVQIWRIQT------------------------TSDNRNNLSWDIHYWI 81
H FA G+ AG+Q+WRI+ T+ ++ +H+W+
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLMLHTAKTSRGFTYHLHFWL 66
Query: 82 GRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGGNPSGF 141
G+E +QDES AAAI TV +DD GG VQ+RE G+ES F+SYF+ L Y GG SG
Sbjct: 67 GKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASGL 126
Query: 142 NHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVE 201
NHV+TN KR+ VKG+R VR +V S NKGD F++DL +IY + G E
Sbjct: 127 NHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYE 186
Query: 202 KLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQE 261
+LKA A +R + GR + +V++ S ++ K G K +PD GGDD +
Sbjct: 187 RLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL-----GEKPELPD---GGDDDD 238
Query: 262 FERNEASNVI--LSEVSDATGKIKVTPLSK--PF------------------------KQ 293
+ ++ + L VSDA+G ++VT +++ PF K
Sbjct: 239 IIADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKG 298
Query: 294 ENLSPQEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 344
++ +PQE+ AM A+E L NY Q+ + + E FKQ+F WRD
Sbjct: 299 KDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRD 349
Score = 64.9 bits (151), Expect = 4e-10
Identities = 47/130 (36%), Positives = 63/130 (48%), Gaps = 7/130 (5%)
Query: 77 IHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQ-TPLNYLEG 135
I+ W G +T+DE +A LTV LD GG AVQ R + G E LS F+ PL +
Sbjct: 437 IYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKN 496
Query: 136 GNPSGFNHVVTNAGAQKRMFQVKGK--RDVRVRQVDPQIASMNKGDVFVLDL-DNDIYVF 192
G R+FQV+ R+ +VD S+N DVFVL L N Y++
Sbjct: 497 GTSKKGGQA---PAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIW 553
Query: 193 VGEKAKNVEK 202
VG+ A E+
Sbjct: 554 VGKGASQEEE 563
Score = 32.7 bits (71), Expect = 2.0
Identities = 14/44 (31%), Positives = 25/44 (56%)
Query: 179 DVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGR 222
DV +LD I++++G+ A VEK +++ A + D GR +
Sbjct: 644 DVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGRDK 687
>AF276507-1|AAK60494.1| 715|Homo sapiens scinderin protein.
Length = 715
Score = 176 bits (429), Expect = 8e-44
Identities = 120/351 (34%), Positives = 175/351 (49%), Gaps = 60/351 (17%)
Query: 46 HPAFANVGRTAGVQIWRIQT------------------------TSDNRNNLSWDIHYWI 81
H FA G+ AG+Q+WRI+ T+ ++ +H+W+
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 66
Query: 82 GRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGGNPSGF 141
G+E +QDES AAAI TV +DD GG VQ+RE G+ES F+SYF+ L Y GG SG
Sbjct: 67 GKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASGL 126
Query: 142 NHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVE 201
NHV+TN KR+ VKG+R VR +V S NKGD F++DL +IY + G E
Sbjct: 127 NHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYE 186
Query: 202 KLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQE 261
+LKA A +R + GR + +V++ S ++ K G K +PD GGDD +
Sbjct: 187 RLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL-----GEKPELPD---GGDDDD 238
Query: 262 FERNEASNVI--LSEVSDATGKIKVTPLSK--PF------------------------KQ 293
+ ++ + L VSDA+G ++VT +++ PF K
Sbjct: 239 IIADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKG 298
Query: 294 ENLSPQEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 344
++ +PQE+ AM A+E L NY Q+ + + E FKQ+F WRD
Sbjct: 299 KDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRD 349
Score = 62.1 bits (144), Expect = 3e-09
Identities = 46/130 (35%), Positives = 62/130 (47%), Gaps = 7/130 (5%)
Query: 77 IHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQT-PLNYLEG 135
I+ W G +T+DE +A LTV LD GG AVQ R + E LS F+ PL +
Sbjct: 437 IYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQDKEPVHLLSLFKDKPLIIYKN 496
Query: 136 GNPSGFNHVVTNAGAQKRMFQVKGKRD--VRVRQVDPQIASMNKGDVFVLDL-DNDIYVF 192
G R+FQV+ R+ +VD S+N DVFVL L N Y++
Sbjct: 497 GTSKKGGQA---PAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLSQNSGYIW 553
Query: 193 VGEKAKNVEK 202
VG+ A E+
Sbjct: 554 VGKGASQEEE 563
Score = 32.7 bits (71), Expect = 2.0
Identities = 14/44 (31%), Positives = 25/44 (56%)
Query: 179 DVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGR 222
DV +LD I++++G+ A VEK +++ A + D GR +
Sbjct: 644 DVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGRDK 687
>AC005281-1|AAD15423.1| 527|Homo sapiens WUGSC:H_DJ0722F20.1
protein.
Length = 527
Score = 176 bits (429), Expect = 8e-44
Identities = 120/351 (34%), Positives = 175/351 (49%), Gaps = 60/351 (17%)
Query: 46 HPAFANVGRTAGVQIWRIQT------------------------TSDNRNNLSWDIHYWI 81
H FA G+ AG+Q+WRI+ T+ ++ +H+W+
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 66
Query: 82 GRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGGNPSGF 141
G+E +QDES AAAI TV +DD GG VQ+RE G+ES F+SYF+ L Y GG SG
Sbjct: 67 GKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASGL 126
Query: 142 NHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVE 201
NHV+TN KR+ VKG+R VR +V S NKGD F++DL +IY + G E
Sbjct: 127 NHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYE 186
Query: 202 KLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQE 261
+LKA A +R + GR + +V++ S ++ K G K +PD GGDD +
Sbjct: 187 RLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL-----GEKPELPD---GGDDDD 238
Query: 262 FERNEASNVI--LSEVSDATGKIKVTPLSK--PF------------------------KQ 293
+ ++ + L VSDA+G ++VT +++ PF K
Sbjct: 239 IIADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKG 298
Query: 294 ENLSPQEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 344
++ +PQE+ AM A+E L NY Q+ + + E FKQ+F WRD
Sbjct: 299 KDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRD 349
Score = 44.8 bits (101), Expect = 5e-04
Identities = 26/61 (42%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Query: 77 IHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQ-TPLNYLEG 135
I+ W G +T+DE +A LTV LD GG AVQ R + G E LS F+ PL +
Sbjct: 437 IYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKN 496
Query: 136 G 136
G
Sbjct: 497 G 497
>AB067492-1|BAB67798.1| 626|Homo sapiens KIAA1905 protein protein.
Length = 626
Score = 176 bits (429), Expect = 8e-44
Identities = 120/351 (34%), Positives = 175/351 (49%), Gaps = 60/351 (17%)
Query: 46 HPAFANVGRTAGVQIWRIQT------------------------TSDNRNNLSWDIHYWI 81
H FA G+ AG+Q+WRI+ T+ ++ +H+W+
Sbjct: 53 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 112
Query: 82 GRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGGNPSGF 141
G+E +QDES AAAI TV +DD GG VQ+RE G+ES F+SYF+ L Y GG SG
Sbjct: 113 GKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASGL 172
Query: 142 NHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVE 201
NHV+TN KR+ VKG+R VR +V S NKGD F++DL +IY + G E
Sbjct: 173 NHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYE 232
Query: 202 KLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQE 261
+LKA A +R + GR + +V++ S ++ K G K +PD GGDD +
Sbjct: 233 RLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL-----GEKPELPD---GGDDDD 284
Query: 262 FERNEASNVI--LSEVSDATGKIKVTPLSK--PF------------------------KQ 293
+ ++ + L VSDA+G ++VT +++ PF K
Sbjct: 285 IIADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKG 344
Query: 294 ENLSPQEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 344
++ +PQE+ AM A+E L NY Q+ + + E FKQ+F WRD
Sbjct: 345 KDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRD 395
Score = 44.8 bits (101), Expect = 5e-04
Identities = 26/61 (42%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Query: 77 IHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQ-TPLNYLEG 135
I+ W G +T+DE +A LTV LD GG AVQ R + G E LS F+ PL +
Sbjct: 483 IYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKN 542
Query: 136 G 136
G
Sbjct: 543 G 543
>BC021090-1|AAH21090.1| 715|Homo sapiens SCIN protein protein.
Length = 715
Score = 176 bits (428), Expect = 1e-43
Identities = 120/351 (34%), Positives = 175/351 (49%), Gaps = 60/351 (17%)
Query: 46 HPAFANVGRTAGVQIWRIQT------------------------TSDNRNNLSWDIHYWI 81
H FA G+ AG+Q+WRI+ T+ ++ +H+W+
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYRLHFWL 66
Query: 82 GRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGGNPSGF 141
G+E +QDES AAAI TV +DD GG VQ+RE G+ES F+SYF+ L Y GG SG
Sbjct: 67 GKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASGL 126
Query: 142 NHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVE 201
NHV+TN KR+ VKG+R VR +V S NKGD F++DL +IY + G E
Sbjct: 127 NHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYE 186
Query: 202 KLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQE 261
+LKA A +R + GR + +V++ S ++ K G K +PD GGDD +
Sbjct: 187 RLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL-----GEKPELPD---GGDDDD 238
Query: 262 FERNEASNVI--LSEVSDATGKIKVTPLSK--PF------------------------KQ 293
+ ++ + L VSDA+G ++VT +++ PF K
Sbjct: 239 IIADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKG 298
Query: 294 ENLSPQEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 344
++ +PQE+ AM A+E L NY Q+ + + E FKQ+F WRD
Sbjct: 299 KDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRD 349
Score = 64.9 bits (151), Expect = 4e-10
Identities = 47/130 (36%), Positives = 63/130 (48%), Gaps = 7/130 (5%)
Query: 77 IHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQ-TPLNYLEG 135
I+ W G +T+DE +A LTV LD GG AVQ R + G E LS F+ PL +
Sbjct: 437 IYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKN 496
Query: 136 GNPSGFNHVVTNAGAQKRMFQVKGK--RDVRVRQVDPQIASMNKGDVFVLDL-DNDIYVF 192
G R+FQV+ R+ +VD S+N DVFVL L N Y++
Sbjct: 497 GTSKKGGQA---PAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIW 553
Query: 193 VGEKAKNVEK 202
VG+ A E+
Sbjct: 554 VGKGASQEEE 563
Score = 32.7 bits (71), Expect = 2.0
Identities = 14/44 (31%), Positives = 25/44 (56%)
Query: 179 DVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGR 222
DV +LD I++++G+ A VEK +++ A + D GR +
Sbjct: 644 DVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGRDK 687
>BC111730-1|AAI11731.1| 812|Homo sapiens AVIL protein protein.
Length = 812
Score = 175 bits (425), Expect = 3e-43
Identities = 110/299 (36%), Positives = 159/299 (53%), Gaps = 36/299 (12%)
Query: 73 LSWDIHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNY 132
LS DIH+WIG++S+QDE AAI T LDD GG+ VQHRE HES F YF+ + Y
Sbjct: 48 LSQDIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIY 107
Query: 133 LEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVF 192
+GG SG HV TN KR+ VKGKR++R +V+ S N+GDVF+LDL I +
Sbjct: 108 KQGGVASGMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQW 167
Query: 193 VGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIV--DKYSSDVDVQKFF-TALG--SGVK 247
G ++ + E+LKA+ A +RD++ GR + ++ DK ++ ++ K LG S +K
Sbjct: 168 NGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIK 227
Query: 248 DLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL-SKPFKQENL---------- 296
VPDE ++ + S ++L +SD+ G++ VT + ++P Q+ L
Sbjct: 228 PTVPDEI-------IDQKQKSTIMLYHISDSAGQLAVTEVATRPLVQDLLNHDDCYILDQ 280
Query: 297 -------------SPQEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 342
+ EK AM+KA + K+YPS V V E A FKQ F W
Sbjct: 281 SGTKIYVWKGKGATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKW 339
Score = 70.1 bits (164), Expect = 1e-11
Identities = 45/140 (32%), Positives = 71/140 (50%), Gaps = 5/140 (3%)
Query: 77 IHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGG 136
++ W GR ++QDE A+A V +D +F GAAVQ R MG E F++ F+ L EGG
Sbjct: 433 LYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVIFEGG 492
Query: 137 NPSGFNHVVTNAGAQKRMFQVKG--KRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVG 194
N R+FQ+ G K + + +V +S+N DVF+L + Y++ G
Sbjct: 493 TSRKGN---AEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHYLWYG 549
Query: 195 EKAKNVEKLKAISFANQVRD 214
+ + E+ A A+ + D
Sbjct: 550 KGSSGDERAMAKELASLLCD 569
>AF041449-1|AAC25051.1| 819|Homo sapiens advillin protein.
Length = 819
Score = 175 bits (425), Expect = 3e-43
Identities = 110/299 (36%), Positives = 159/299 (53%), Gaps = 36/299 (12%)
Query: 73 LSWDIHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNY 132
LS DIH+WIG++S+QDE AAI T LDD GG+ VQHRE HES F YF+ + Y
Sbjct: 55 LSQDIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIY 114
Query: 133 LEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVF 192
+GG SG HV TN KR+ VKGKR++R +V+ S N+GDVF+LDL I +
Sbjct: 115 KQGGVASGMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQW 174
Query: 193 VGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIV--DKYSSDVDVQKFF-TALG--SGVK 247
G ++ + E+LKA+ A +RD++ GR + ++ DK ++ ++ K LG S +K
Sbjct: 175 NGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIK 234
Query: 248 DLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL-SKPFKQENL---------- 296
VPDE ++ + S ++L +SD+ G++ VT + ++P Q+ L
Sbjct: 235 PTVPDEI-------IDQKQKSTIMLYHISDSAGQLAVTEVATRPLVQDLLNHDDCYILDQ 287
Query: 297 -------------SPQEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 342
+ EK AM+KA + K+YPS V V E A FKQ F W
Sbjct: 288 SGTKIYVWKGKGATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKW 346
Score = 67.3 bits (157), Expect = 8e-11
Identities = 44/140 (31%), Positives = 70/140 (50%), Gaps = 5/140 (3%)
Query: 77 IHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGG 136
++ W R ++QDE A+A V +D +F GAAVQ R MG E F++ F+ L EGG
Sbjct: 440 LYIWQDRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVIFEGG 499
Query: 137 NPSGFNHVVTNAGAQKRMFQVKG--KRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVG 194
N R+FQ+ G K + + +V +S+N DVF+L + Y++ G
Sbjct: 500 TSRKGN---AEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHYLWYG 556
Query: 195 EKAKNVEKLKAISFANQVRD 214
+ + E+ A A+ + D
Sbjct: 557 KGSSGDERAMAKELASLLCD 576
>AL513122-5|CAI14415.1| 260|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 260
Score = 169 bits (411), Expect = 1e-41
Identities = 80/166 (48%), Positives = 105/166 (63%)
Query: 63 IQTTSDNRNNLSWDIHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALF 122
++T NL +D+HYW+G E +QDESGAAAI TV LDD G AVQHRE G ESA F
Sbjct: 47 LKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATF 106
Query: 123 LSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFV 182
L YF++ L Y +GG SGF HVV N +R+FQVKG+R VR +V S N GD F+
Sbjct: 107 LGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFI 166
Query: 183 LDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDK 228
LDL N+I+ + G + E+LKA + +RD + GR RV + ++
Sbjct: 167 LDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEE 212
>AL513122-4|CAI14414.1| 228|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 228
Score = 169 bits (411), Expect = 1e-41
Identities = 80/166 (48%), Positives = 105/166 (63%)
Query: 63 IQTTSDNRNNLSWDIHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALF 122
++T NL +D+HYW+G E +QDESGAAAI TV LDD G AVQHRE G ESA F
Sbjct: 58 LKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATF 117
Query: 123 LSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFV 182
L YF++ L Y +GG SGF HVV N +R+FQVKG+R VR +V S N GD F+
Sbjct: 118 LGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFI 177
Query: 183 LDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDK 228
LDL N+I+ + G + E+LKA + +RD + GR RV + ++
Sbjct: 178 LDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEE 223
>X12901-1|CAA31386.1| 827|Homo sapiens protein ( Human mRNA for
villin. ).
Length = 827
Score = 154 bits (374), Expect = 4e-37
Identities = 104/296 (35%), Positives = 151/296 (51%), Gaps = 26/296 (8%)
Query: 71 NNLSWDIHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPL 130
++LS+DIHYWIG++S+ DE GAAAI T +DD G AVQHRE G+ES F YF+ L
Sbjct: 56 SSLSYDIHYWIGQDSSLDEQGAAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGL 115
Query: 131 NYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIY 190
+GG SG HV TN+ +R+ VKGKR+V +V+ S N+GDVF+LDL I
Sbjct: 116 VIRKGGVASGMKHVETNSYDVQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLII 175
Query: 191 VFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLV 250
+ G ++ +E+L+ ++ A ++RDQ+ GR V +VD +++ K + + V
Sbjct: 176 QWNGPESTRMERLRGMTLAKEIRDQERGGRTYVGVVDG-ENELASPKLMEVM-NHVLGKR 233
Query: 251 PDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL-SKPFKQENLS------------ 297
+ D E + + L VSD+ G + V + ++P Q+ LS
Sbjct: 234 RELKAAVPDTVVEPALKAALKLYHVSDSEGNLVVREVATRPLTQDLLSHEDCYILDQGGL 293
Query: 298 -----------PQEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 342
QEK AM+ A + AK YP QV E A F+Q F W
Sbjct: 294 KIYVWKGKKANEQEKKGAMSHALNFIKAKQYPPSTQVEVQNDGAESAVFQQLFQKW 349
Score = 65.7 bits (153), Expect = 2e-10
Identities = 75/291 (25%), Positives = 126/291 (43%), Gaps = 26/291 (8%)
Query: 77 IHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGG 136
++ W G +++QDE A+A V LD K+ G VQ R MG E +S F+ + +GG
Sbjct: 443 LYVWQGSQASQDEITASAYQAVILDQKYNGEPVQIRVPMGKEPPHLMSIFKGRMVVYQGG 502
Query: 137 NPSGFNHVVTNAGAQKRMFQVK--GKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVG 194
S N++ T G R+FQV+ G + + +V + +N DVFVL + Y++ G
Sbjct: 503 T-SRTNNLET--GPSTRLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQSCCYLWCG 559
Query: 195 EKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDES 254
+ E+ A V D +V + + ++ + A + K L +E+
Sbjct: 560 KGCSGDER----EMAKMVADTISRTEKQVVVEGQEPANFWMALGGKAPYANTKRL-QEEN 614
Query: 255 TGGDDQEFE-RNEASNVILSEVSDATGK---------IKVTPLSKPFKQENLSPQEKSQA 304
+ FE N+ + +E+ D + V + ++ + +EK A
Sbjct: 615 LVITPRLFECSNKTGRFLATEIPDFNQDDLEEDDVFLLDVWDQVFFWIGKHANEEEKKAA 674
Query: 305 MTKAQELLNAKNYPSW----VQVTRVLQNTEPAAFKQYFFTWRDFGMSHSR 351
T AQE L K +PS + V Q EP F +F W F S+++
Sbjct: 675 ATTAQEYL--KTHPSGRDPETPIIVVKQGHEPPTFTGWFLAWDPFKWSNTK 723
>BC017303-1|AAH17303.1| 421|Homo sapiens VIL1 protein protein.
Length = 421
Score = 154 bits (374), Expect = 4e-37
Identities = 104/296 (35%), Positives = 151/296 (51%), Gaps = 26/296 (8%)
Query: 71 NNLSWDIHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPL 130
++LS+DIHYWIG++S+ DE GAAAI T +DD G AVQHRE G+ES F YF+ L
Sbjct: 56 SSLSYDIHYWIGQDSSLDEQGAAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGL 115
Query: 131 NYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIY 190
+GG SG HV TN+ +R+ VKGKR+V +V+ S N+GDVF+LDL I
Sbjct: 116 VIRKGGVASGMKHVETNSYDVQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLII 175
Query: 191 VFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLV 250
+ G ++ +E+L+ ++ A ++RDQ+ GR V +VD +++ K + + V
Sbjct: 176 QWNGPESTRMERLRGMTLAKEIRDQERGGRTYVGVVDG-ENELASPKLMEVM-NHVLGKR 233
Query: 251 PDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL-SKPFKQENLS------------ 297
+ D E + + L VSD+ G + V + ++P Q+ LS
Sbjct: 234 RELKAAVPDTVVEPALKAALKLYHVSDSEGNLVVREVATRPLTQDLLSHEDCYILDQGGL 293
Query: 298 -----------PQEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 342
QEK AM+ A + AK YP QV E A F+Q F W
Sbjct: 294 KIYVWKGKKANEQEKKGAMSHALNFIKAKQYPPSTQVEVQNDGAESAVFQQLFQKW 349
>AK223398-1|BAD97118.1| 827|Homo sapiens villin 1 variant protein.
Length = 827
Score = 154 bits (374), Expect = 4e-37
Identities = 104/296 (35%), Positives = 151/296 (51%), Gaps = 26/296 (8%)
Query: 71 NNLSWDIHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPL 130
++LS+DIHYWIG++S+ DE GAAAI T +DD G AVQHRE G+ES F YF+ L
Sbjct: 56 SSLSYDIHYWIGQDSSLDEQGAAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGL 115
Query: 131 NYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIY 190
+GG SG HV TN+ +R+ VKGKR+V +V+ S N+GDVF+LDL I
Sbjct: 116 VIRKGGVASGMKHVETNSYDVQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLII 175
Query: 191 VFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLV 250
+ G ++ +E+L+ ++ A ++RDQ+ GR V +VD +++ K + + V
Sbjct: 176 QWNGPESTRMERLRGMTLAKEIRDQERGGRTYVGVVDG-ENELASPKLMEVM-NHVLGKR 233
Query: 251 PDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL-SKPFKQENLS------------ 297
+ D E + + L VSD+ G + V + ++P Q+ LS
Sbjct: 234 RELKAAVPDTVVEPALKAALKLYHVSDSEGNLVVREVATRPLTQDLLSHEDCYILDQGGL 293
Query: 298 -----------PQEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 342
QEK AM+ A + AK YP QV E A F+Q F W
Sbjct: 294 KIYVWKGKKANEQEKKGAMSHALNFIKAKQYPPSTQVEVQNDGAESAVFQQLFQKW 349
Score = 65.7 bits (153), Expect = 2e-10
Identities = 75/291 (25%), Positives = 126/291 (43%), Gaps = 26/291 (8%)
Query: 77 IHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGG 136
++ W G +++QDE A+A V LD K+ G VQ R MG E +S F+ + +GG
Sbjct: 443 LYVWQGSQASQDEITASAYQAVILDQKYNGEPVQIRVPMGKEPPHLMSIFKGRMVVYQGG 502
Query: 137 NPSGFNHVVTNAGAQKRMFQVK--GKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVG 194
S N++ T G R+FQV+ G + + +V + +N DVFVL + Y++ G
Sbjct: 503 T-SRTNNLET--GPSTRLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQSCCYLWCG 559
Query: 195 EKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDES 254
+ E+ A V D +V + + ++ + A + K L +E+
Sbjct: 560 KGCSGDER----EMAKMVADTISRTEKQVVVEGQEPANFWMALGGKAPYANTKRL-QEEN 614
Query: 255 TGGDDQEFE-RNEASNVILSEVSDATGK---------IKVTPLSKPFKQENLSPQEKSQA 304
+ FE N+ + +E+ D + V + ++ + +EK A
Sbjct: 615 LVITPRLFECSNKTGRFLATEIPDFNQDDLEEDDVFLLDVWDQVFFWIGKHANEEEKKAA 674
Query: 305 MTKAQELLNAKNYPSW----VQVTRVLQNTEPAAFKQYFFTWRDFGMSHSR 351
T AQE L K +PS + V Q EP F +F W F S+++
Sbjct: 675 ATTAQEYL--KTHPSGRDPETPIIVVKQGHEPPTFTGWFLAWDPFKWSNTK 723
>M94345-1|AAA59570.1| 348|Homo sapiens macrophage capping protein
protein.
Length = 348
Score = 141 bits (342), Expect = 3e-33
Identities = 96/294 (32%), Positives = 147/294 (50%), Gaps = 33/294 (11%)
Query: 77 IHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGG 136
+H WIG++S++DE GA A+L V L+ G VQHRE G+ES LF+SYF L Y EGG
Sbjct: 61 LHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 120
Query: 137 NPSGFNHVVTNA-GAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGE 195
S F+ T A A K+++QVKGK+++R + S N GD F+LDL +I+ + G
Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180
Query: 196 KAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDEST 255
K+ +E+ KA A +RD + G+ +V+IV ++ + G K + E
Sbjct: 181 KSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVL-----GPKPAL-KEGN 234
Query: 256 GGDDQEFERNEASNVILSEVSDATGKIKVTPL--SKPFKQENL----------------- 296
+D ++ A L +VSDATG++ +T + S PF E L
Sbjct: 235 PEEDLTADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIY 294
Query: 297 -------SPQEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWR 343
+ +E+ A+ A+ ++ Y QV + Q E FKQ+F W+
Sbjct: 295 IWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGRESPIFKQFFKDWK 348
>BC014549-1|AAH14549.1| 348|Homo sapiens capping protein (actin
filament), gelsolin-like protein.
Length = 348
Score = 141 bits (342), Expect = 3e-33
Identities = 96/294 (32%), Positives = 147/294 (50%), Gaps = 33/294 (11%)
Query: 77 IHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGG 136
+H WIG++S++DE GA A+L V L+ G VQHRE G+ES LF+SYF L Y EGG
Sbjct: 61 LHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 120
Query: 137 NPSGFNHVVTNA-GAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGE 195
S F+ T A A K+++QVKGK+++R + S N GD F+LDL +I+ + G
Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180
Query: 196 KAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDEST 255
K+ +E+ KA A +RD + G+ +V+IV ++ + G K + E
Sbjct: 181 KSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVL-----GPKPAL-KEGN 234
Query: 256 GGDDQEFERNEASNVILSEVSDATGKIKVTPL--SKPFKQENL----------------- 296
+D ++ A L +VSDATG++ +T + S PF E L
Sbjct: 235 PEEDLTADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIY 294
Query: 297 -------SPQEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWR 343
+ +E+ A+ A+ ++ Y QV + Q E FKQ+F W+
Sbjct: 295 IWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGRESPIFKQFFKDWK 348
>BC000728-1|AAH00728.1| 348|Homo sapiens capping protein (actin
filament), gelsolin-like protein.
Length = 348
Score = 141 bits (342), Expect = 3e-33
Identities = 96/294 (32%), Positives = 147/294 (50%), Gaps = 33/294 (11%)
Query: 77 IHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGG 136
+H WIG++S++DE GA A+L V L+ G VQHRE G+ES LF+SYF L Y EGG
Sbjct: 61 LHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 120
Query: 137 NPSGFNHVVTNA-GAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGE 195
S F+ T A A K+++QVKGK+++R + S N GD F+LDL +I+ + G
Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180
Query: 196 KAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDEST 255
K+ +E+ KA A +RD + G+ +V+IV ++ + G K + E
Sbjct: 181 KSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVL-----GPKPAL-KEGN 234
Query: 256 GGDDQEFERNEASNVILSEVSDATGKIKVTPL--SKPFKQENL----------------- 296
+D ++ A L +VSDATG++ +T + S PF E L
Sbjct: 235 PEEDLTADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIY 294
Query: 297 -------SPQEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWR 343
+ +E+ A+ A+ ++ Y QV + Q E FKQ+F W+
Sbjct: 295 IWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGRESPIFKQFFKDWK 348
>AC062037-3|AAY24128.1| 348|Homo sapiens unknown protein.
Length = 348
Score = 141 bits (341), Expect = 4e-33
Identities = 96/294 (32%), Positives = 147/294 (50%), Gaps = 33/294 (11%)
Query: 77 IHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGG 136
+H WIG++S++DE GA A+L V L+ G VQHRE G+ES LF+SYF L Y EGG
Sbjct: 61 LHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 120
Query: 137 NPSGFNHVVTNA-GAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGE 195
S F+ T A A K+++QVKGK+++R + S N GD F+LDL +I+ + G
Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGG 180
Query: 196 KAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDEST 255
K+ +E+ KA A +RD + G+ +V+IV ++ + G K + E
Sbjct: 181 KSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVL-----GPKPAL-KEGN 234
Query: 256 GGDDQEFERNEASNVILSEVSDATGKIKVTPL--SKPFKQENL----------------- 296
+D ++ A L +VSDATG++ +T + S PF E L
Sbjct: 235 PEEDLTADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIY 294
Query: 297 -------SPQEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWR 343
+ +E+ A+ A+ ++ Y QV + Q E FKQ+F W+
Sbjct: 295 IWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDWK 348
>AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog
variant protein.
Length = 1101
Score = 111 bits (267), Expect = 4e-24
Identities = 78/261 (29%), Positives = 134/261 (51%), Gaps = 19/261 (7%)
Query: 63 IQTTSDNRNNLSWDIHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALF 122
++T D+ +L+W+I+YWIG E+T D+ +AI V L + G RE MG ES F
Sbjct: 518 LKTFLDDSGSLNWEIYYWIGGEATLDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEF 577
Query: 123 LSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFV 182
L F ++Y+EGG SGF + V + RM++V GK+++++ V + S++ VF+
Sbjct: 578 LQVFDNDISYIEGGTASGF-YTVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFL 636
Query: 183 LDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTAL 242
LD DIYV+ G +A KA FA ++ + G+ + ++ ++ +F+ AL
Sbjct: 637 LDRGLDIYVWRGAQATLSSTTKARLFAEKINKNERKGKAEITLL---VQGQELPEFWEAL 693
Query: 243 GSGVKDLVPDESTGGDD---QEFERNEASNVILSEVSDATGKIKVTPLSKPFKQENLS-- 297
G P E DD ++ RN A V+ S +GK+K K + +L+
Sbjct: 694 GG-----EPSEIKNWDDVLTVDYTRN-AEAVLQS--PGLSGKVKRDAEKKDQMKADLTAL 745
Query: 298 --PQEKSQAMTKAQELLNAKN 316
P++ ++ +A++L+ N
Sbjct: 746 FLPRQPPMSLAEAEQLMEEWN 766
>U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein.
Length = 1269
Score = 110 bits (265), Expect = 6e-24
Identities = 64/194 (32%), Positives = 107/194 (55%), Gaps = 7/194 (3%)
Query: 63 IQTTSDNRNNLSWDIHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALF 122
++T D+ +L+W+I+YWIG E+T D+ +AI V L + G RE MG ES F
Sbjct: 531 LKTFLDDSGSLNWEIYYWIGGEATLDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEF 590
Query: 123 LSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFV 182
L F ++Y+EGG SGF + V + RM++V GK+++++ V + S++ VF+
Sbjct: 591 LQVFDNDISYIEGGTASGF-YTVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFL 649
Query: 183 LDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTAL 242
LD DIYV+ G +A KA FA ++ + G+ + ++ ++ +F+ AL
Sbjct: 650 LDRGLDIYVWRGAQATLSSTTKARLFAEKINKNERKGKAEITLL---VQGQELPEFWEAL 706
Query: 243 G---SGVKDLVPDE 253
G S +K VP++
Sbjct: 707 GGEPSEIKKHVPED 720
>U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog
protein.
Length = 1268
Score = 110 bits (265), Expect = 6e-24
Identities = 64/194 (32%), Positives = 107/194 (55%), Gaps = 7/194 (3%)
Query: 63 IQTTSDNRNNLSWDIHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALF 122
++T D+ +L+W+I+YWIG E+T D+ +AI V L + G RE MG ES F
Sbjct: 530 LKTFLDDSGSLNWEIYYWIGGEATLDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEF 589
Query: 123 LSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFV 182
L F ++Y+EGG SGF + V + RM++V GK+++++ V + S++ VF+
Sbjct: 590 LQVFDNDISYIEGGTASGF-YTVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFL 648
Query: 183 LDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTAL 242
LD DIYV+ G +A KA FA ++ + G+ + ++ ++ +F+ AL
Sbjct: 649 LDRGLDIYVWRGAQATLSSTTKARLFAEKINKNERKGKAEITLL---VQGQELPEFWEAL 705
Query: 243 G---SGVKDLVPDE 253
G S +K VP++
Sbjct: 706 GGEPSEIKKHVPED 719
>BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog
(Drosophila) protein.
Length = 1269
Score = 110 bits (265), Expect = 6e-24
Identities = 64/194 (32%), Positives = 107/194 (55%), Gaps = 7/194 (3%)
Query: 63 IQTTSDNRNNLSWDIHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALF 122
++T D+ +L+W+I+YWIG E+T D+ +AI V L + G RE MG ES F
Sbjct: 531 LKTFLDDSGSLNWEIYYWIGGEATLDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEF 590
Query: 123 LSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFV 182
L F ++Y+EGG SGF + V + RM++V GK+++++ V + S++ VF+
Sbjct: 591 LQVFDNDISYIEGGTASGF-YTVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFL 649
Query: 183 LDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTAL 242
LD DIYV+ G +A KA FA ++ + G+ + ++ ++ +F+ AL
Sbjct: 650 LDRGLDIYVWRGAQATLSSTTKARLFAEKINKNERKGKAEITLL---VQGQELPEFWEAL 706
Query: 243 G---SGVKDLVPDE 253
G S +K VP++
Sbjct: 707 GGEPSEIKKHVPED 720
>U12026-1|AAA92670.1| 172|Homo sapiens Cap-G protein.
Length = 172
Score = 105 bits (251), Expect = 3e-22
Identities = 52/110 (47%), Positives = 70/110 (63%), Gaps = 1/110 (0%)
Query: 77 IHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGG 136
+H WIG++S++DE GA A+L V L+ G VQHRE G+ES LF+SYF L Y EGG
Sbjct: 61 LHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGG 120
Query: 137 NPSGFNHVVTNA-GAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVFVLDL 185
S F+ T A A K+++QVKGK+++R + S N GD F+LDL
Sbjct: 121 VESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDL 170
>AL513122-7|CAI14416.1| 485|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 485
Score = 77.8 bits (183), Expect = 5e-14
Identities = 51/142 (35%), Positives = 69/142 (48%), Gaps = 6/142 (4%)
Query: 77 IHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYF-QTPLNYLEG 135
I+ W G +STQDE A+AILT LD++ GG VQ R G E A +S F P+ +G
Sbjct: 221 IYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKG 280
Query: 136 GNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVD--PQIASMNKGDVFVLDLDNDIYVFV 193
G A A R+FQV+ R V+ P+ ++N D FVL + Y++V
Sbjct: 281 GTSREGGQ---TAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWV 337
Query: 194 GEKAKNVEKLKAISFANQVRDQ 215
G A EK A +R Q
Sbjct: 338 GTGASEAEKTGAQELLRVLRAQ 359
Score = 38.7 bits (86), Expect = 0.030
Identities = 16/54 (29%), Positives = 29/54 (53%)
Query: 291 FKQENLSPQEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 344
+K + + +E+ A+ A + + +YP QV+ + + E FKQ+F WRD
Sbjct: 76 WKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRD 129
>BC017491-1|AAH17491.1| 285|Homo sapiens Similar to gelsolin
(amyloidosis, Finnish type) protein.
Length = 285
Score = 70.1 bits (164), Expect = 1e-11
Identities = 48/134 (35%), Positives = 64/134 (47%), Gaps = 6/134 (4%)
Query: 85 STQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYF-QTPLNYLEGGNPSGFNH 143
STQDE A+AILT LD++ GG VQ R G E A +S F P+ +GG
Sbjct: 1 STQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQ 60
Query: 144 VVTNAGAQKRMFQVKGKRDVRVRQVD--PQIASMNKGDVFVLDLDNDIYVFVGEKAKNVE 201
A A R+FQV+ R V+ P+ ++N D FVL + Y++VG A E
Sbjct: 61 ---TAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAE 117
Query: 202 KLKAISFANQVRDQ 215
K A +R Q
Sbjct: 118 KTGAQELLRVLRAQ 131
Score = 30.7 bits (66), Expect = 8.1
Identities = 14/44 (31%), Positives = 27/44 (61%)
Query: 179 DVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGR 222
DV +LD + ++V+VG+ ++ EK +A++ A + + D R R
Sbjct: 200 DVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDR 243
>AK075198-1|BAC11465.1| 396|Homo sapiens protein ( Homo sapiens
cDNA FLJ90717 fis, clone PLACE1008657, highly similar to
Bovine mRNA for adseverin. ).
Length = 396
Score = 64.9 bits (151), Expect = 4e-10
Identities = 47/130 (36%), Positives = 63/130 (48%), Gaps = 7/130 (5%)
Query: 77 IHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQ-TPLNYLEG 135
I+ W G +T+DE +A LTV LD GG AVQ R + G E LS F+ PL +
Sbjct: 118 IYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKN 177
Query: 136 GNPSGFNHVVTNAGAQKRMFQVKGK--RDVRVRQVDPQIASMNKGDVFVLDL-DNDIYVF 192
G R+FQV+ R+ +VD S+N DVFVL L N Y++
Sbjct: 178 GTSKKGGQA---PAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIW 234
Query: 193 VGEKAKNVEK 202
VG+ A E+
Sbjct: 235 VGKGASQEEE 244
Score = 32.7 bits (71), Expect = 2.0
Identities = 14/44 (31%), Positives = 25/44 (56%)
Query: 179 DVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGR 222
DV +LD I++++G+ A VEK +++ A + D GR +
Sbjct: 325 DVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGRDK 368
>AK027778-1|BAB55361.1| 468|Homo sapiens protein ( Homo sapiens
cDNA FLJ14872 fis, clone PLACE1002655, highly similar to
ADSEVERIN. ).
Length = 468
Score = 64.9 bits (151), Expect = 4e-10
Identities = 47/130 (36%), Positives = 63/130 (48%), Gaps = 7/130 (5%)
Query: 77 IHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQT-PLNYLEG 135
I+ W G +T+DE +A LTV LD GG AVQ R + G E LS F+ PL +
Sbjct: 190 IYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKN 249
Query: 136 GNPSGFNHVVTNAGAQKRMFQVKGKRD--VRVRQVDPQIASMNKGDVFVLDL-DNDIYVF 192
G R+FQV+ R+ +VD S+N DVFVL L N Y++
Sbjct: 250 GTSKKGGQA---PAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIW 306
Query: 193 VGEKAKNVEK 202
VG+ A E+
Sbjct: 307 VGKGASQEEE 316
Score = 44.0 bits (99), Expect = 8e-04
Identities = 20/54 (37%), Positives = 30/54 (55%)
Query: 291 FKQENLSPQEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 344
+K ++ +PQE+ AM A+E L NY Q+ + + E FKQ+F WRD
Sbjct: 49 WKGKDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRD 102
Score = 32.7 bits (71), Expect = 2.0
Identities = 14/44 (31%), Positives = 25/44 (56%)
Query: 179 DVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGR 222
DV +LD I++++G+ A VEK +++ A + D GR +
Sbjct: 397 DVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGRDK 440
>D88154-1|BAA21668.1| 686|Homo sapiens villin-like protein protein.
Length = 686
Score = 58.0 bits (134), Expect = 5e-08
Identities = 39/145 (26%), Positives = 68/145 (46%), Gaps = 5/145 (3%)
Query: 53 GRTAGVQIWRIQTTSDNRNNLSWDIHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHR 112
G+ + + T + + ++ W G ++T DE A LD +GG VQ
Sbjct: 242 GQLCAGNCYLVLYTYQRLGRVQYILYLWQGHQATADEIEALNSNAEELDVMYGGVLVQEH 301
Query: 113 ETMGHESALFLSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKG--KRDVRVRQVDP 170
TMG E FL+ FQ L + +G +H + + R+FQV+G + R +V
Sbjct: 302 VTMGSEPPHFLAIFQGQLVIFQ--ERAG-HHGKGQSASTTRLFQVQGTDSHNTRTMEVPA 358
Query: 171 QIASMNKGDVFVLDLDNDIYVFVGE 195
+ +S+N D+F+L + Y++ G+
Sbjct: 359 RASSLNSSDIFLLVTASVCYLWFGK 383
Score = 42.3 bits (95), Expect = 0.002
Identities = 20/48 (41%), Positives = 27/48 (56%)
Query: 297 SPQEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 344
S QE+ A ++A + AK YP++ V V E AAFKQ F TW +
Sbjct: 132 SLQERKAAFSRAVGFIQAKGYPTYTNVEVVNDGAESAAFKQLFRTWSE 179
>BC004300-1|AAH04300.1| 672|Homo sapiens VILL protein protein.
Length = 672
Score = 58.0 bits (134), Expect = 5e-08
Identities = 39/145 (26%), Positives = 68/145 (46%), Gaps = 5/145 (3%)
Query: 53 GRTAGVQIWRIQTTSDNRNNLSWDIHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHR 112
G+ + + T + + ++ W G ++T DE A LD +GG VQ
Sbjct: 228 GQLCAGNCYLVLYTYQRLGRVQYILYLWQGHQATADEIEALNSNAEELDVMYGGVLVQEH 287
Query: 113 ETMGHESALFLSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKG--KRDVRVRQVDP 170
TMG E FL+ FQ L + +G +H + + R+FQV+G + R +V
Sbjct: 288 VTMGSEPPHFLAIFQGQLVIFQ--ERAG-HHGKGQSASTTRLFQVQGTDSHNTRTMEVPA 344
Query: 171 QIASMNKGDVFVLDLDNDIYVFVGE 195
+ +S+N D+F+L + Y++ G+
Sbjct: 345 RASSLNSSDIFLLVTASVCYLWFGK 369
Score = 46.8 bits (106), Expect = 1e-04
Identities = 43/159 (27%), Positives = 70/159 (44%), Gaps = 8/159 (5%)
Query: 194 GEKAKNVEKLKAISFANQVRDQDHHG-RGRVDIVDKYSSDVDVQKFFTA-LGSGVKDLVP 251
G K EK + ++ +RD++ G R ++ +VD + D+ + A LG V L
Sbjct: 7 GPKTSISEKARGLALTYSLRDRERGGGRAQIGVVDDEAKAPDLMQIMEAVLGRRVGSLRA 66
Query: 252 DESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLSKP-FK----QENLSP-QEKSQAM 305
+ +Q + N + + D + L + FK Q +S QE+ A
Sbjct: 67 ATPSKDINQLQKANVRLYHVYEKGKDLLQEEDFYILDQGGFKIYVWQGRMSSLQERKAAF 126
Query: 306 TKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 344
++A + AK YP++ V V E AAFKQ F TW +
Sbjct: 127 SRAVGFIQAKGYPTYTNVEVVNDGAESAAFKQLFRTWSE 165
>BC000243-1|AAH00243.1| 686|Homo sapiens VILL protein protein.
Length = 686
Score = 58.0 bits (134), Expect = 5e-08
Identities = 39/145 (26%), Positives = 68/145 (46%), Gaps = 5/145 (3%)
Query: 53 GRTAGVQIWRIQTTSDNRNNLSWDIHYWIGRESTQDESGAAAILTVGLDDKFGGAAVQHR 112
G+ + + T + + ++ W G ++T DE A LD +GG VQ
Sbjct: 242 GQLCAGNCYLVLYTYQRLGRVQYILYLWQGHQATADEIEALNSNAEELDVMYGGVLVQEH 301
Query: 113 ETMGHESALFLSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKG--KRDVRVRQVDP 170
TMG E FL+ FQ L + +G +H + + R+FQV+G + R +V
Sbjct: 302 VTMGSEPPHFLAIFQGQLVIFQ--ERAG-HHGKGQSASTTRLFQVQGTDSHNTRTMEVPA 358
Query: 171 QIASMNKGDVFVLDLDNDIYVFVGE 195
+ +S+N D+F+L + Y++ G+
Sbjct: 359 RASSLNSSDIFLLVTASVCYLWFGK 383
Score = 42.3 bits (95), Expect = 0.002
Identities = 20/48 (41%), Positives = 27/48 (56%)
Query: 297 SPQEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 344
S QE+ A ++A + AK YP++ V V E AAFKQ F TW +
Sbjct: 132 SLQERKAAFSRAVGFIQAKGYPTYTNVEVVNDGAESAAFKQLFRTWSE 179
>AL160060-2|CAH71301.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 50.0 bits (114), Expect = 1e-05
Identities = 23/66 (34%), Positives = 41/66 (62%)
Query: 154 MFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVR 213
+ Q+KG+R V+ R V+P+ +++N GD F+L + +++VGE A +EK KA A ++
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 214 DQDHHG 219
+ G
Sbjct: 1079 TKRELG 1084
Score = 43.2 bits (97), Expect = 0.001
Identities = 41/141 (29%), Positives = 72/141 (51%), Gaps = 11/141 (7%)
Query: 79 YWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGGNP 138
+W GR ST E G +A++TV LD++ GA VQ G E FL FQ + G
Sbjct: 1389 FWQGRHSTVSEKGTSALMTVELDEE-RGAQVQ--VLQGKEPPCFLQCFQGGMVVHSGRR- 1444
Query: 139 SGFNHVVTNAGAQKRMFQVKGKRDV--RVRQVDPQIASM-NKGDVFVLDLDND-IYVFVG 194
N ++ R++ V+G+ V + +V +S+ ++ + VL+++ IY++ G
Sbjct: 1445 ---EEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWHG 1501
Query: 195 EKAKNVEKLKAISFANQVRDQ 215
KA+ K + AN++++Q
Sbjct: 1502 CKAQAHTKEVGRTAANKIKEQ 1522
>AL160060-1|CAH71300.1| 2214|Homo sapiens supervillin protein.
Length = 2214
Score = 50.0 bits (114), Expect = 1e-05
Identities = 23/66 (34%), Positives = 41/66 (62%)
Query: 154 MFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVR 213
+ Q+KG+R V+ R V+P+ +++N GD F+L + +++VGE A +EK KA A ++
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 214 DQDHHG 219
+ G
Sbjct: 1505 TKRELG 1510
Score = 43.2 bits (97), Expect = 0.001
Identities = 41/141 (29%), Positives = 72/141 (51%), Gaps = 11/141 (7%)
Query: 79 YWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGGNP 138
+W GR ST E G +A++TV LD++ GA VQ G E FL FQ + G
Sbjct: 1815 FWQGRHSTVSEKGTSALMTVELDEE-RGAQVQ--VLQGKEPPCFLQCFQGGMVVHSGRR- 1870
Query: 139 SGFNHVVTNAGAQKRMFQVKGKRDV--RVRQVDPQIASM-NKGDVFVLDLDND-IYVFVG 194
N ++ R++ V+G+ V + +V +S+ ++ + VL+++ IY++ G
Sbjct: 1871 ---EEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWHG 1927
Query: 195 EKAKNVEKLKAISFANQVRDQ 215
KA+ K + AN++++Q
Sbjct: 1928 CKAQAHTKEVGRTAANKIKEQ 1948
>AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein.
Length = 2214
Score = 50.0 bits (114), Expect = 1e-05
Identities = 23/66 (34%), Positives = 41/66 (62%)
Query: 154 MFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVR 213
+ Q+KG+R V+ R V+P+ +++N GD F+L + +++VGE A +EK KA A ++
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 214 DQDHHG 219
+ G
Sbjct: 1505 TKRELG 1510
Score = 43.2 bits (97), Expect = 0.001
Identities = 41/141 (29%), Positives = 72/141 (51%), Gaps = 11/141 (7%)
Query: 79 YWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGGNP 138
+W GR ST E G +A++TV LD++ GA VQ G E FL FQ + G
Sbjct: 1815 FWQGRHSTVSEKGTSALMTVELDEE-RGAQVQ--VLQGKEPPCFLQCFQGGMVVHSGRR- 1870
Query: 139 SGFNHVVTNAGAQKRMFQVKGKRDV--RVRQVDPQIASM-NKGDVFVLDLDND-IYVFVG 194
N ++ R++ V+G+ V + +V +S+ ++ + VL+++ IY++ G
Sbjct: 1871 ---EEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWHG 1927
Query: 195 EKAKNVEKLKAISFANQVRDQ 215
KA+ K + AN++++Q
Sbjct: 1928 CKAQAHTKEVGRTAANKIKEQ 1948
>AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 50.0 bits (114), Expect = 1e-05
Identities = 23/66 (34%), Positives = 41/66 (62%)
Query: 154 MFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVR 213
+ Q+KG+R V+ R V+P+ +++N GD F+L + +++VGE A +EK KA A ++
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 214 DQDHHG 219
+ G
Sbjct: 1079 TKRELG 1084
Score = 43.2 bits (97), Expect = 0.001
Identities = 41/141 (29%), Positives = 72/141 (51%), Gaps = 11/141 (7%)
Query: 79 YWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGGNP 138
+W GR ST E G +A++TV LD++ GA VQ G E FL FQ + G
Sbjct: 1389 FWQGRHSTVSEKGTSALMTVELDEE-RGAQVQ--VLQGKEPPCFLQCFQGGMVVHSGRR- 1444
Query: 139 SGFNHVVTNAGAQKRMFQVKGKRDV--RVRQVDPQIASM-NKGDVFVLDLDND-IYVFVG 194
N ++ R++ V+G+ V + +V +S+ ++ + VL+++ IY++ G
Sbjct: 1445 ---EEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWHG 1501
Query: 195 EKAKNVEKLKAISFANQVRDQ 215
KA+ K + AN++++Q
Sbjct: 1502 CKAQAHTKEVGRTAANKIKEQ 1522
>AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein.
Length = 2214
Score = 50.0 bits (114), Expect = 1e-05
Identities = 23/66 (34%), Positives = 41/66 (62%)
Query: 154 MFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVR 213
+ Q+KG+R V+ R V+P+ +++N GD F+L + +++VGE A +EK KA A ++
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 214 DQDHHG 219
+ G
Sbjct: 1505 TKRELG 1510
Score = 43.2 bits (97), Expect = 0.001
Identities = 41/141 (29%), Positives = 72/141 (51%), Gaps = 11/141 (7%)
Query: 79 YWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGGNP 138
+W GR ST E G +A++TV LD++ GA VQ G E FL FQ + G
Sbjct: 1815 FWQGRHSTVSEKGTSALMTVELDEE-RGAQVQ--VLQGKEPPCFLQCFQGGMVVHSGRR- 1870
Query: 139 SGFNHVVTNAGAQKRMFQVKGKRDV--RVRQVDPQIASM-NKGDVFVLDLDND-IYVFVG 194
N ++ R++ V+G+ V + +V +S+ ++ + VL+++ IY++ G
Sbjct: 1871 ---EEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWHG 1927
Query: 195 EKAKNVEKLKAISFANQVRDQ 215
KA+ K + AN++++Q
Sbjct: 1928 CKAQAHTKEVGRTAANKIKEQ 1948
>AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 50.0 bits (114), Expect = 1e-05
Identities = 23/66 (34%), Positives = 41/66 (62%)
Query: 154 MFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVR 213
+ Q+KG+R V+ R V+P+ +++N GD F+L + +++VGE A +EK KA A ++
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 214 DQDHHG 219
+ G
Sbjct: 1079 TKRELG 1084
Score = 43.2 bits (97), Expect = 0.001
Identities = 41/141 (29%), Positives = 72/141 (51%), Gaps = 11/141 (7%)
Query: 79 YWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGGNP 138
+W GR ST E G +A++TV LD++ GA VQ G E FL FQ + G
Sbjct: 1389 FWQGRHSTVSEKGTSALMTVELDEE-RGAQVQ--VLQGKEPPCFLQCFQGGMVVHSGRR- 1444
Query: 139 SGFNHVVTNAGAQKRMFQVKGKRDV--RVRQVDPQIASM-NKGDVFVLDLDND-IYVFVG 194
N ++ R++ V+G+ V + +V +S+ ++ + VL+++ IY++ G
Sbjct: 1445 ---EEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWHG 1501
Query: 195 EKAKNVEKLKAISFANQVRDQ 215
KA+ K + AN++++Q
Sbjct: 1502 CKAQAHTKEVGRTAANKIKEQ 1522
>AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 50.0 bits (114), Expect = 1e-05
Identities = 23/66 (34%), Positives = 41/66 (62%)
Query: 154 MFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVR 213
+ Q+KG+R V+ R V+P+ +++N GD F+L + +++VGE A +EK KA A ++
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 214 DQDHHG 219
+ G
Sbjct: 1079 TKRELG 1084
Score = 43.2 bits (97), Expect = 0.001
Identities = 41/141 (29%), Positives = 72/141 (51%), Gaps = 11/141 (7%)
Query: 79 YWIGRESTQDESGAAAILTVGLDDKFGGAAVQHRETMGHESALFLSYFQTPLNYLEGGNP 138
+W GR ST E G +A++TV LD++ GA VQ G E FL FQ + G
Sbjct: 1389 FWQGRHSTVSEKGTSALMTVELDEE-RGAQVQ--VLQGKEPPCFLQCFQGGMVVHSGRR- 1444
Query: 139 SGFNHVVTNAGAQKRMFQVKGKRDV--RVRQVDPQIASM-NKGDVFVLDLDND-IYVFVG 194
N ++ R++ V+G+ V + +V +S+ ++ + VL+++ IY++ G
Sbjct: 1445 ---EEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWHG 1501
Query: 195 EKAKNVEKLKAISFANQVRDQ 215
KA+ K + AN++++Q
Sbjct: 1502 CKAQAHTKEVGRTAANKIKEQ 1522
>AL590005-3|CAI14988.1| 5457|Homo sapiens dystonin protein.
Length = 5457
Score = 31.1 bits (67), Expect = 6.1
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 5/47 (10%)
Query: 283 KVTPLSKPFKQENLSPQEKSQAMTKAQELLNA-----KNYPSWVQVT 324
K LSK FK+ + +EK +A+T QE L+A K+ SW++ T
Sbjct: 2259 KTNNLSKKFKEMEDTIKEKKEAVTSCQEQLDAFQVLVKSLKSWIKET 2305
>AL590005-2|CAI14989.1| 7543|Homo sapiens dystonin protein.
Length = 7543
Score = 31.1 bits (67), Expect = 6.1
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 5/47 (10%)
Query: 283 KVTPLSKPFKQENLSPQEKSQAMTKAQELLNA-----KNYPSWVQVT 324
K LSK FK+ + +EK +A+T QE L+A K+ SW++ T
Sbjct: 4345 KTNNLSKKFKEMEDTIKEKKEAVTSCQEQLDAFQVLVKSLKSWIKET 4391
>AL512448-3|CAI16610.1| 5144|Homo sapiens dystonin protein.
Length = 5144
Score = 31.1 bits (67), Expect = 6.1
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 5/47 (10%)
Query: 283 KVTPLSKPFKQENLSPQEKSQAMTKAQELLNA-----KNYPSWVQVT 324
K LSK FK+ + +EK +A+T QE L+A K+ SW++ T
Sbjct: 1933 KTNNLSKKFKEMEDTIKEKKEAVTSCQEQLDAFQVLVKSLKSWIKET 1979
>AL512448-2|CAI16608.1| 5457|Homo sapiens dystonin protein.
Length = 5457
Score = 31.1 bits (67), Expect = 6.1
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 5/47 (10%)
Query: 283 KVTPLSKPFKQENLSPQEKSQAMTKAQELLNA-----KNYPSWVQVT 324
K LSK FK+ + +EK +A+T QE L+A K+ SW++ T
Sbjct: 2259 KTNNLSKKFKEMEDTIKEKKEAVTSCQEQLDAFQVLVKSLKSWIKET 2305
>AL512448-1|CAI16609.1| 7543|Homo sapiens dystonin protein.
Length = 7543
Score = 31.1 bits (67), Expect = 6.1
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 5/47 (10%)
Query: 283 KVTPLSKPFKQENLSPQEKSQAMTKAQELLNA-----KNYPSWVQVT 324
K LSK FK+ + +EK +A+T QE L+A K+ SW++ T
Sbjct: 4345 KTNNLSKKFKEMEDTIKEKKEAVTSCQEQLDAFQVLVKSLKSWIKET 4391
>AL512422-3|CAI14342.1| 5457|Homo sapiens dystonin protein.
Length = 5457
Score = 31.1 bits (67), Expect = 6.1
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 5/47 (10%)
Query: 283 KVTPLSKPFKQENLSPQEKSQAMTKAQELLNA-----KNYPSWVQVT 324
K LSK FK+ + +EK +A+T QE L+A K+ SW++ T
Sbjct: 2259 KTNNLSKKFKEMEDTIKEKKEAVTSCQEQLDAFQVLVKSLKSWIKET 2305
>AL512422-2|CAI14341.1| 7543|Homo sapiens dystonin protein.
Length = 7543
Score = 31.1 bits (67), Expect = 6.1
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 5/47 (10%)
Query: 283 KVTPLSKPFKQENLSPQEKSQAMTKAQELLNA-----KNYPSWVQVT 324
K LSK FK+ + +EK +A+T QE L+A K+ SW++ T
Sbjct: 4345 KTNNLSKKFKEMEDTIKEKKEAVTSCQEQLDAFQVLVKSLKSWIKET 4391
>AL137008-4|CAI20332.1| 5144|Homo sapiens dystonin protein.
Length = 5144
Score = 31.1 bits (67), Expect = 6.1
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 5/47 (10%)
Query: 283 KVTPLSKPFKQENLSPQEKSQAMTKAQELLNA-----KNYPSWVQVT 324
K LSK FK+ + +EK +A+T QE L+A K+ SW++ T
Sbjct: 1933 KTNNLSKKFKEMEDTIKEKKEAVTSCQEQLDAFQVLVKSLKSWIKET 1979
>AL137008-3|CAI20331.1| 5457|Homo sapiens dystonin protein.
Length = 5457
Score = 31.1 bits (67), Expect = 6.1
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 5/47 (10%)
Query: 283 KVTPLSKPFKQENLSPQEKSQAMTKAQELLNA-----KNYPSWVQVT 324
K LSK FK+ + +EK +A+T QE L+A K+ SW++ T
Sbjct: 2259 KTNNLSKKFKEMEDTIKEKKEAVTSCQEQLDAFQVLVKSLKSWIKET 2305
>AL137008-2|CAI20330.1| 7543|Homo sapiens dystonin protein.
Length = 7543
Score = 31.1 bits (67), Expect = 6.1
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 5/47 (10%)
Query: 283 KVTPLSKPFKQENLSPQEKSQAMTKAQELLNA-----KNYPSWVQVT 324
K LSK FK+ + +EK +A+T QE L+A K+ SW++ T
Sbjct: 4345 KTNNLSKKFKEMEDTIKEKKEAVTSCQEQLDAFQVLVKSLKSWIKET 4391
>AL096710-4|CAI22045.1| 5144|Homo sapiens dystonin protein.
Length = 5144
Score = 31.1 bits (67), Expect = 6.1
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 5/47 (10%)
Query: 283 KVTPLSKPFKQENLSPQEKSQAMTKAQELLNA-----KNYPSWVQVT 324
K LSK FK+ + +EK +A+T QE L+A K+ SW++ T
Sbjct: 1933 KTNNLSKKFKEMEDTIKEKKEAVTSCQEQLDAFQVLVKSLKSWIKET 1979
>AL096710-3|CAI22044.1| 7543|Homo sapiens dystonin protein.
Length = 7543
Score = 31.1 bits (67), Expect = 6.1
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 5/47 (10%)
Query: 283 KVTPLSKPFKQENLSPQEKSQAMTKAQELLNA-----KNYPSWVQVT 324
K LSK FK+ + +EK +A+T QE L+A K+ SW++ T
Sbjct: 4345 KTNNLSKKFKEMEDTIKEKKEAVTSCQEQLDAFQVLVKSLKSWIKET 4391
>AL096710-2|CAI22043.1| 5457|Homo sapiens dystonin protein.
Length = 5457
Score = 31.1 bits (67), Expect = 6.1
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 5/47 (10%)
Query: 283 KVTPLSKPFKQENLSPQEKSQAMTKAQELLNA-----KNYPSWVQVT 324
K LSK FK+ + +EK +A+T QE L+A K+ SW++ T
Sbjct: 2259 KTNNLSKKFKEMEDTIKEKKEAVTSCQEQLDAFQVLVKSLKSWIKET 2305
>AK094883-1|BAC04449.1| 775|Homo sapiens protein ( Homo sapiens
cDNA FLJ37564 fis, clone BRCOC2000816, weakly similar to
Homo sapiens mRNA for actin binding protein ABP620. ).
Length = 775
Score = 31.1 bits (67), Expect = 6.1
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 5/47 (10%)
Query: 283 KVTPLSKPFKQENLSPQEKSQAMTKAQELLNA-----KNYPSWVQVT 324
K LSK FK+ + +EK +A+T QE L+A K+ SW++ T
Sbjct: 177 KTNNLSKKFKEMEDTIKEKKEAVTSCQEQLDAFQVLVKSLKSWIKET 223
>AF400226-1|AAL62061.1| 5171|Homo sapiens bullous pemphigoid antigen 1
eA protein.
Length = 5171
Score = 31.1 bits (67), Expect = 6.1
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 5/47 (10%)
Query: 283 KVTPLSKPFKQENLSPQEKSQAMTKAQELLNA-----KNYPSWVQVT 324
K LSK FK+ + +EK +A+T QE L+A K+ SW++ T
Sbjct: 1933 KTNNLSKKFKEMEDTIKEKKEAVTSCQEQLDAFQVLVKSLKSWIKET 1979
>AL513122-9|CAI14417.1| 207|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 207
Score = 30.7 bits (66), Expect = 8.1
Identities = 14/44 (31%), Positives = 27/44 (61%)
Query: 179 DVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGR 222
DV +LD + ++V+VG+ ++ EK +A++ A + + D R R
Sbjct: 122 DVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDR 165
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.316 0.132 0.385
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 50,955,185
Number of Sequences: 224733
Number of extensions: 2072389
Number of successful extensions: 4143
Number of sequences better than 10.0: 55
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 3945
Number of HSP's gapped (non-prelim): 183
length of query: 353
length of database: 73,234,838
effective HSP length: 91
effective length of query: 262
effective length of database: 52,784,135
effective search space: 13829443370
effective search space used: 13829443370
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 66 (30.7 bits)
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