Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001754-TA|BGIBMGA001754-PA|IPR007122|Gelsolin,
IPR007123|Gelsolin region
(527 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X04412-1|CAA28000.1| 782|Homo sapiens plasma gelsolin protein. 123 2e-27
BC026033-1|AAH26033.1| 782|Homo sapiens gelsolin (amyloidosis, ... 123 2e-27
AL513122-6|CAM20459.1| 731|Homo sapiens gelsolin (amyloidosis, ... 123 2e-27
AL513122-5|CAI14415.1| 260|Homo sapiens gelsolin (amyloidosis, ... 123 2e-27
AL513122-4|CAI14414.1| 228|Homo sapiens gelsolin (amyloidosis, ... 123 2e-27
AL513122-3|CAI14413.1| 782|Homo sapiens gelsolin (amyloidosis, ... 123 2e-27
BC021090-1|AAH21090.1| 715|Homo sapiens SCIN protein protein. 119 2e-26
AK075123-1|BAC11416.1| 715|Homo sapiens protein ( Homo sapiens ... 119 2e-26
AF276507-1|AAK60494.1| 715|Homo sapiens scinderin protein. 119 2e-26
AC005281-1|AAD15423.1| 527|Homo sapiens WUGSC:H_DJ0722F20.1 pro... 119 2e-26
AB067492-1|BAB67798.1| 626|Homo sapiens KIAA1905 protein protein. 119 2e-26
M94345-1|AAA59570.1| 348|Homo sapiens macrophage capping protei... 119 3e-26
BC014549-1|AAH14549.1| 348|Homo sapiens capping protein (actin ... 119 3e-26
BC000728-1|AAH00728.1| 348|Homo sapiens capping protein (actin ... 119 3e-26
AC062037-3|AAY24128.1| 348|Homo sapiens unknown protein. 118 4e-26
BC111730-1|AAI11731.1| 812|Homo sapiens AVIL protein protein. 118 5e-26
AF041449-1|AAC25051.1| 819|Homo sapiens advillin protein. 118 5e-26
X12901-1|CAA31386.1| 827|Homo sapiens protein ( Human mRNA for ... 108 5e-23
BC017303-1|AAH17303.1| 421|Homo sapiens VIL1 protein protein. 108 5e-23
AK223398-1|BAD97118.1| 827|Homo sapiens villin 1 variant protein. 108 5e-23
U12026-1|AAA92670.1| 172|Homo sapiens Cap-G protein. 89 5e-17
BC000243-1|AAH00243.1| 686|Homo sapiens VILL protein protein. 83 2e-15
D88154-1|BAA21668.1| 686|Homo sapiens villin-like protein protein. 83 2e-15
U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. 82 4e-15
U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot... 82 4e-15
BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D... 82 4e-15
AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va... 82 4e-15
AK027778-1|BAB55361.1| 468|Homo sapiens protein ( Homo sapiens ... 78 7e-14
BC075797-1|AAH75797.1| 85|Homo sapiens Unknown (protein for MG... 73 3e-12
AL513122-7|CAI14416.1| 485|Homo sapiens gelsolin (amyloidosis, ... 72 4e-12
X07066-1|CAA30102.1| 69|Homo sapiens protein ( Human gene for ... 71 8e-12
BC004300-1|AAH04300.1| 672|Homo sapiens VILL protein protein. 71 1e-11
BC017491-1|AAH17491.1| 285|Homo sapiens Similar to gelsolin (am... 68 9e-11
AL513122-9|CAI14417.1| 207|Homo sapiens gelsolin (amyloidosis, ... 67 1e-10
AK075198-1|BAC11465.1| 396|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AL160060-2|CAH71301.1| 1788|Homo sapiens supervillin protein. 50 3e-05
AL160060-1|CAH71300.1| 2214|Homo sapiens supervillin protein. 50 3e-05
AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein. 50 3e-05
AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein. 50 3e-05
AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein. 50 3e-05
AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein. 50 3e-05
AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein. 50 3e-05
AL513122-8|CAI14418.1| 188|Homo sapiens gelsolin (amyloidosis, ... 39 0.038
CR457114-1|CAG33395.1| 364|Homo sapiens HAVCR1 protein. 35 0.62
BC013325-1|AAH13325.1| 364|Homo sapiens HAVCR1 protein protein. 35 0.62
U78550-1|AAC51342.1| 328|Homo sapiens mucin MUC5B protein. 34 1.1
AK022448-1|BAB14038.1| 126|Homo sapiens protein ( Homo sapiens ... 33 1.9
Z72496-1|CAA96577.1| 3570|Homo sapiens mucin MUC5B protein. 32 4.3
X74955-1|CAA52910.1| 622|Homo sapiens mucin protein. 32 4.3
AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ ... 32 5.7
AF007192-1|AAC02270.1| 338|Homo sapiens intestinal mucin protein. 32 5.7
>X04412-1|CAA28000.1| 782|Homo sapiens plasma gelsolin protein.
Length = 782
Score = 123 bits (296), Expect = 2e-27
Identities = 57/107 (53%), Positives = 76/107 (71%), Gaps = 2/107 (1%)
Query: 5 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 63
H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W
Sbjct: 56 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 115
Query: 64 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF
Sbjct: 116 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYF 161
Score = 114 bits (274), Expect = 8e-25
Identities = 64/206 (31%), Positives = 109/206 (52%), Gaps = 9/206 (4%)
Query: 323 VFVSKVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRAD 382
V ++V ++ES NNGDCFILD+ + I + G + ER+KA V+ I+D + +GRA
Sbjct: 198 VRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRAR 257
Query: 383 IEVVDSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSI 442
+ V + + LG K A+ E D + + K L ++S+ G++
Sbjct: 258 VHVSEEGTEP---EAMLQVLGP--KPALPAGTE--DTAKEDAANRKLAKLYKVSNGAGTM 310
Query: 443 RITRLPA--PLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKYHD 500
++ + P + L +++C++LD G I+VW G+ +N +E+ A+ A ++ D
Sbjct: 311 SVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMD 370
Query: 501 YPAWVHVSKVPEGAEPIPFKQYFEDW 526
YP VS +PEG E FKQ+F++W
Sbjct: 371 YPKQTQVSVLPEGGETPLFKQFFKNW 396
Score = 71.3 bits (167), Expect = 8e-12
Identities = 39/93 (41%), Positives = 51/93 (54%), Gaps = 1/93 (1%)
Query: 18 EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 77
+IWRIE V V +G FY GDSYI+L R I+ W G++++QDE A+A
Sbjct: 448 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 507
Query: 78 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
ILT L DE+ G+ VQ R VQ E + F
Sbjct: 508 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLF 539
Score = 67.7 bits (158), Expect = 9e-11
Identities = 55/203 (27%), Positives = 96/203 (47%), Gaps = 20/203 (9%)
Query: 327 KVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVV 386
+V P +LN+ D F+L +++VG A E+ A + ++ Q ++V
Sbjct: 580 EVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQP------VQVA 633
Query: 387 DSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIRITR 446
+ DG F++ALG K A + D +++ L S+K G I
Sbjct: 634 EGSEPDG----FWEALGG--KAAYRTSPRLKD----KKMDAHPPRLFACSNKIGRFVIEE 683
Query: 447 LPAPLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKYH--DYPAW 504
+P L +E L TD+ +LDT + ++VWVG+ S +EK EA+ A++Y++ +
Sbjct: 684 VPGELMQEDLATDDVMLLDT--WDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRR 741
Query: 505 VHVSKVPEGAEPIPFKQYFEDWN 527
++ V +G EP F +F W+
Sbjct: 742 TPITVVKQGFEPPSFVGWFLGWD 764
Score = 48.8 bits (111), Expect = 5e-05
Identities = 22/39 (56%), Positives = 28/39 (71%)
Query: 150 IRYLKGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQV 188
++Y KGG ASGF HV NE +RLFQ+KG+R VR +V
Sbjct: 165 LKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEV 203
Score = 45.6 bits (103), Expect = 4e-04
Identities = 31/105 (29%), Positives = 52/105 (49%), Gaps = 7/105 (6%)
Query: 414 EEGGDDQEFERVVTKEVSLSEISDKTGSIRITRLPAPLKKEQLNTDECYVLDTGSYSGIY 473
++GG F+ VV EV + + G + P+ E N +C++LD G + I+
Sbjct: 168 KKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLG--NNIH 225
Query: 474 VWVGRGSNLKEKAEAMNRAEQYLKYHDYP--AWVHVSKVPEGAEP 516
W G SN E+ +A + + ++ ++ A VHVS+ EG EP
Sbjct: 226 QWCGSNSNRYERLKA-TQVSKGIRDNERSGRARVHVSE--EGTEP 267
>BC026033-1|AAH26033.1| 782|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 782
Score = 123 bits (296), Expect = 2e-27
Identities = 57/107 (53%), Positives = 76/107 (71%), Gaps = 2/107 (1%)
Query: 5 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 63
H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W
Sbjct: 56 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 115
Query: 64 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF
Sbjct: 116 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYF 161
Score = 114 bits (274), Expect = 8e-25
Identities = 64/206 (31%), Positives = 109/206 (52%), Gaps = 9/206 (4%)
Query: 323 VFVSKVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRAD 382
V ++V ++ES NNGDCFILD+ + I + G + ER+KA V+ I+D + +GRA
Sbjct: 198 VRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRAR 257
Query: 383 IEVVDSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSI 442
+ V + + LG K A+ E D + + K L ++S+ G++
Sbjct: 258 VHVSEEGTEP---EAMLQVLGP--KPALPAGTE--DTAKEDAANRKLAKLYKVSNGAGTM 310
Query: 443 RITRLPA--PLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKYHD 500
++ + P + L +++C++LD G I+VW G+ +N +E+ A+ A ++ D
Sbjct: 311 SVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMD 370
Query: 501 YPAWVHVSKVPEGAEPIPFKQYFEDW 526
YP VS +PEG E FKQ+F++W
Sbjct: 371 YPKQTQVSVLPEGGETPLFKQFFKNW 396
Score = 71.3 bits (167), Expect = 8e-12
Identities = 39/93 (41%), Positives = 51/93 (54%), Gaps = 1/93 (1%)
Query: 18 EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 77
+IWRIE V V +G FY GDSYI+L R I+ W G++++QDE A+A
Sbjct: 448 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 507
Query: 78 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
ILT L DE+ G+ VQ R VQ E + F
Sbjct: 508 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLF 539
Score = 67.7 bits (158), Expect = 9e-11
Identities = 55/203 (27%), Positives = 96/203 (47%), Gaps = 20/203 (9%)
Query: 327 KVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVV 386
+V P +LN+ D F+L +++VG A E+ A + ++ Q ++V
Sbjct: 580 EVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQP------VQVA 633
Query: 387 DSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIRITR 446
+ DG F++ALG K A + D +++ L S+K G I
Sbjct: 634 EGSEPDG----FWEALGG--KAAYRTSPRLKD----KKMDAHPPRLFACSNKIGRFVIEE 683
Query: 447 LPAPLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKYH--DYPAW 504
+P L +E L TD+ +LDT + ++VWVG+ S +EK EA+ A++Y++ +
Sbjct: 684 VPGELMQEDLATDDVMLLDT--WDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRR 741
Query: 505 VHVSKVPEGAEPIPFKQYFEDWN 527
++ V +G EP F +F W+
Sbjct: 742 TPITVVKQGFEPPSFVGWFLGWD 764
Score = 48.8 bits (111), Expect = 5e-05
Identities = 22/39 (56%), Positives = 28/39 (71%)
Query: 150 IRYLKGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQV 188
++Y KGG ASGF HV NE +RLFQ+KG+R VR +V
Sbjct: 165 LKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEV 203
Score = 45.6 bits (103), Expect = 4e-04
Identities = 31/105 (29%), Positives = 52/105 (49%), Gaps = 7/105 (6%)
Query: 414 EEGGDDQEFERVVTKEVSLSEISDKTGSIRITRLPAPLKKEQLNTDECYVLDTGSYSGIY 473
++GG F+ VV EV + + G + P+ E N +C++LD G + I+
Sbjct: 168 KKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLG--NNIH 225
Query: 474 VWVGRGSNLKEKAEAMNRAEQYLKYHDYP--AWVHVSKVPEGAEP 516
W G SN E+ +A + + ++ ++ A VHVS+ EG EP
Sbjct: 226 QWCGSNSNRYERLKA-TQVSKGIRDNERSGRARVHVSE--EGTEP 267
>AL513122-6|CAM20459.1| 731|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 731
Score = 123 bits (296), Expect = 2e-27
Identities = 57/107 (53%), Positives = 76/107 (71%), Gaps = 2/107 (1%)
Query: 5 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 63
H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W
Sbjct: 5 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 64
Query: 64 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF
Sbjct: 65 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYF 110
Score = 114 bits (274), Expect = 8e-25
Identities = 64/206 (31%), Positives = 109/206 (52%), Gaps = 9/206 (4%)
Query: 323 VFVSKVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRAD 382
V ++V ++ES NNGDCFILD+ + I + G + ER+KA V+ I+D + +GRA
Sbjct: 147 VRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRAR 206
Query: 383 IEVVDSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSI 442
+ V + + LG K A+ E D + + K L ++S+ G++
Sbjct: 207 VHVSEEGTEP---EAMLQVLGP--KPALPAGTE--DTAKEDAANRKLAKLYKVSNGAGTM 259
Query: 443 RITRLPA--PLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKYHD 500
++ + P + L +++C++LD G I+VW G+ +N +E+ A+ A ++ D
Sbjct: 260 SVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMD 319
Query: 501 YPAWVHVSKVPEGAEPIPFKQYFEDW 526
YP VS +PEG E FKQ+F++W
Sbjct: 320 YPKQTQVSVLPEGGETPLFKQFFKNW 345
Score = 71.3 bits (167), Expect = 8e-12
Identities = 39/93 (41%), Positives = 51/93 (54%), Gaps = 1/93 (1%)
Query: 18 EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 77
+IWRIE V V +G FY GDSYI+L R I+ W G++++QDE A+A
Sbjct: 397 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 456
Query: 78 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
ILT L DE+ G+ VQ R VQ E + F
Sbjct: 457 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLF 488
Score = 67.7 bits (158), Expect = 9e-11
Identities = 55/203 (27%), Positives = 96/203 (47%), Gaps = 20/203 (9%)
Query: 327 KVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVV 386
+V P +LN+ D F+L +++VG A E+ A + ++ Q ++V
Sbjct: 529 EVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQP------VQVA 582
Query: 387 DSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIRITR 446
+ DG F++ALG K A + D +++ L S+K G I
Sbjct: 583 EGSEPDG----FWEALGG--KAAYRTSPRLKD----KKMDAHPPRLFACSNKIGRFVIEE 632
Query: 447 LPAPLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKYH--DYPAW 504
+P L +E L TD+ +LDT + ++VWVG+ S +EK EA+ A++Y++ +
Sbjct: 633 VPGELMQEDLATDDVMLLDT--WDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRR 690
Query: 505 VHVSKVPEGAEPIPFKQYFEDWN 527
++ V +G EP F +F W+
Sbjct: 691 TPITVVKQGFEPPSFVGWFLGWD 713
Score = 48.8 bits (111), Expect = 5e-05
Identities = 22/39 (56%), Positives = 28/39 (71%)
Query: 150 IRYLKGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQV 188
++Y KGG ASGF HV NE +RLFQ+KG+R VR +V
Sbjct: 114 LKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEV 152
Score = 45.6 bits (103), Expect = 4e-04
Identities = 31/105 (29%), Positives = 52/105 (49%), Gaps = 7/105 (6%)
Query: 414 EEGGDDQEFERVVTKEVSLSEISDKTGSIRITRLPAPLKKEQLNTDECYVLDTGSYSGIY 473
++GG F+ VV EV + + G + P+ E N +C++LD G + I+
Sbjct: 117 KKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLG--NNIH 174
Query: 474 VWVGRGSNLKEKAEAMNRAEQYLKYHDYP--AWVHVSKVPEGAEP 516
W G SN E+ +A + + ++ ++ A VHVS+ EG EP
Sbjct: 175 QWCGSNSNRYERLKA-TQVSKGIRDNERSGRARVHVSE--EGTEP 216
>AL513122-5|CAI14415.1| 260|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 260
Score = 123 bits (296), Expect = 2e-27
Identities = 57/107 (53%), Positives = 76/107 (71%), Gaps = 2/107 (1%)
Query: 5 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 63
H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W
Sbjct: 5 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 64
Query: 64 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF
Sbjct: 65 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYF 110
Score = 56.8 bits (131), Expect = 2e-07
Identities = 26/63 (41%), Positives = 40/63 (63%)
Query: 323 VFVSKVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRAD 382
V ++V ++ES NNGDCFILD+ + I + G + ER+KA V+ I+D + +GRA
Sbjct: 147 VRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRAR 206
Query: 383 IEV 385
+ V
Sbjct: 207 VHV 209
Score = 48.8 bits (111), Expect = 5e-05
Identities = 22/39 (56%), Positives = 28/39 (71%)
Query: 150 IRYLKGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQV 188
++Y KGG ASGF HV NE +RLFQ+KG+R VR +V
Sbjct: 114 LKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEV 152
Score = 45.6 bits (103), Expect = 4e-04
Identities = 31/105 (29%), Positives = 52/105 (49%), Gaps = 7/105 (6%)
Query: 414 EEGGDDQEFERVVTKEVSLSEISDKTGSIRITRLPAPLKKEQLNTDECYVLDTGSYSGIY 473
++GG F+ VV EV + + G + P+ E N +C++LD G + I+
Sbjct: 117 KKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLG--NNIH 174
Query: 474 VWVGRGSNLKEKAEAMNRAEQYLKYHDYP--AWVHVSKVPEGAEP 516
W G SN E+ +A + + ++ ++ A VHVS+ EG EP
Sbjct: 175 QWCGSNSNRYERLKA-TQVSKGIRDNERSGRARVHVSE--EGTEP 216
>AL513122-4|CAI14414.1| 228|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 228
Score = 123 bits (296), Expect = 2e-27
Identities = 57/107 (53%), Positives = 76/107 (71%), Gaps = 2/107 (1%)
Query: 5 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 63
H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W
Sbjct: 16 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 75
Query: 64 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF
Sbjct: 76 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYF 121
Score = 56.8 bits (131), Expect = 2e-07
Identities = 26/63 (41%), Positives = 40/63 (63%)
Query: 323 VFVSKVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRAD 382
V ++V ++ES NNGDCFILD+ + I + G + ER+KA V+ I+D + +GRA
Sbjct: 158 VRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRAR 217
Query: 383 IEV 385
+ V
Sbjct: 218 VHV 220
Score = 48.8 bits (111), Expect = 5e-05
Identities = 22/39 (56%), Positives = 28/39 (71%)
Query: 150 IRYLKGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQV 188
++Y KGG ASGF HV NE +RLFQ+KG+R VR +V
Sbjct: 125 LKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEV 163
Score = 45.6 bits (103), Expect = 4e-04
Identities = 31/105 (29%), Positives = 52/105 (49%), Gaps = 7/105 (6%)
Query: 414 EEGGDDQEFERVVTKEVSLSEISDKTGSIRITRLPAPLKKEQLNTDECYVLDTGSYSGIY 473
++GG F+ VV EV + + G + P+ E N +C++LD G + I+
Sbjct: 128 KKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLG--NNIH 185
Query: 474 VWVGRGSNLKEKAEAMNRAEQYLKYHDYP--AWVHVSKVPEGAEP 516
W G SN E+ +A + + ++ ++ A VHVS+ EG EP
Sbjct: 186 QWCGSNSNRYERLKA-TQVSKGIRDNERSGRARVHVSE--EGTEP 227
>AL513122-3|CAI14413.1| 782|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 782
Score = 123 bits (296), Expect = 2e-27
Identities = 57/107 (53%), Positives = 76/107 (71%), Gaps = 2/107 (1%)
Query: 5 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 63
H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W
Sbjct: 56 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 115
Query: 64 LGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
LG+ SQDE+GAAAI TV LDD G AVQHREVQ +ES FL YF
Sbjct: 116 LGNECSQDESGAAAIFTVQLDD-YLNGRAVQHREVQGFESATFLGYF 161
Score = 114 bits (274), Expect = 8e-25
Identities = 64/206 (31%), Positives = 109/206 (52%), Gaps = 9/206 (4%)
Query: 323 VFVSKVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRAD 382
V ++V ++ES NNGDCFILD+ + I + G + ER+KA V+ I+D + +GRA
Sbjct: 198 VRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRAR 257
Query: 383 IEVVDSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSI 442
+ V + + LG K A+ E D + + K L ++S+ G++
Sbjct: 258 VHVSEEGTEP---EAMLQVLGP--KPALPAGTE--DTAKEDAANRKLAKLYKVSNGAGTM 310
Query: 443 RITRLPA--PLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKYHD 500
++ + P + L +++C++LD G I+VW G+ +N +E+ A+ A ++ D
Sbjct: 311 SVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMD 370
Query: 501 YPAWVHVSKVPEGAEPIPFKQYFEDW 526
YP VS +PEG E FKQ+F++W
Sbjct: 371 YPKQTQVSVLPEGGETPLFKQFFKNW 396
Score = 71.3 bits (167), Expect = 8e-12
Identities = 39/93 (41%), Positives = 51/93 (54%), Gaps = 1/93 (1%)
Query: 18 EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 77
+IWRIE V V +G FY GDSYI+L R I+ W G++++QDE A+A
Sbjct: 448 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 507
Query: 78 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
ILT L DE+ G+ VQ R VQ E + F
Sbjct: 508 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLF 539
Score = 67.7 bits (158), Expect = 9e-11
Identities = 55/203 (27%), Positives = 96/203 (47%), Gaps = 20/203 (9%)
Query: 327 KVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVV 386
+V P +LN+ D F+L +++VG A E+ A + ++ Q ++V
Sbjct: 580 EVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQP------VQVA 633
Query: 387 DSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIRITR 446
+ DG F++ALG K A + D +++ L S+K G I
Sbjct: 634 EGSEPDG----FWEALGG--KAAYRTSPRLKD----KKMDAHPPRLFACSNKIGRFVIEE 683
Query: 447 LPAPLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKYH--DYPAW 504
+P L +E L TD+ +LDT + ++VWVG+ S +EK EA+ A++Y++ +
Sbjct: 684 VPGELMQEDLATDDVMLLDT--WDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRR 741
Query: 505 VHVSKVPEGAEPIPFKQYFEDWN 527
++ V +G EP F +F W+
Sbjct: 742 TPITVVKQGFEPPSFVGWFLGWD 764
Score = 48.8 bits (111), Expect = 5e-05
Identities = 22/39 (56%), Positives = 28/39 (71%)
Query: 150 IRYLKGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQV 188
++Y KGG ASGF HV NE +RLFQ+KG+R VR +V
Sbjct: 165 LKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEV 203
Score = 45.6 bits (103), Expect = 4e-04
Identities = 31/105 (29%), Positives = 52/105 (49%), Gaps = 7/105 (6%)
Query: 414 EEGGDDQEFERVVTKEVSLSEISDKTGSIRITRLPAPLKKEQLNTDECYVLDTGSYSGIY 473
++GG F+ VV EV + + G + P+ E N +C++LD G + I+
Sbjct: 168 KKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLG--NNIH 225
Query: 474 VWVGRGSNLKEKAEAMNRAEQYLKYHDYP--AWVHVSKVPEGAEP 516
W G SN E+ +A + + ++ ++ A VHVS+ EG EP
Sbjct: 226 QWCGSNSNRYERLKA-TQVSKGIRDNERSGRARVHVSE--EGTEP 267
>BC021090-1|AAH21090.1| 715|Homo sapiens SCIN protein protein.
Length = 715
Score = 119 bits (287), Expect = 2e-26
Identities = 67/208 (32%), Positives = 113/208 (54%), Gaps = 12/208 (5%)
Query: 323 VFVSKVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRAD 382
V ++V +++S N GDCFI+D+ +I+ + G ER+KA VA I+ + GR++
Sbjct: 148 VRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKGRSE 207
Query: 383 IEVVDSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVT--KEVSLSEISDKTG 440
+ VV+ + + G K + D GGDD + ++ K L +SD +G
Sbjct: 208 LIVVEEGSEPSELIKVL-----GEKPELPD---GGDDDDIIADISNRKMAKLYMVSDASG 259
Query: 441 SIRITRLPA--PLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKY 498
S+R+T + P L ++EC++LD G+ I+VW G+ +N +E+ AM AE++L+
Sbjct: 260 SMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQ 319
Query: 499 HDYPAWVHVSKVPEGAEPIPFKQYFEDW 526
+Y + +PEG E FKQ+F+DW
Sbjct: 320 MNYSKNTQIQVLPEGGETPIFKQFFKDW 347
Score = 116 bits (278), Expect = 3e-25
Identities = 54/106 (50%), Positives = 72/106 (67%), Gaps = 1/106 (0%)
Query: 5 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 64
H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y+VL+T T+ +HFWL
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYRLHFWL 66
Query: 65 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
G SQDE+ AAAI TV +DD G VQ+RE+Q YES +F+ YF
Sbjct: 67 GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYF 111
Score = 60.1 bits (139), Expect = 2e-08
Identities = 40/110 (36%), Positives = 54/110 (49%), Gaps = 7/110 (6%)
Query: 1 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 60
M H D K +EIWR+EN + V + +G FY GD YI+L T + ++ I
Sbjct: 384 MAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI---I 437
Query: 61 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
+ W G+ ++DE +A LTV L D G AVQ R Q E L F
Sbjct: 438 YTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLF 486
Score = 50.4 bits (115), Expect = 2e-05
Identities = 50/212 (23%), Positives = 93/212 (43%), Gaps = 22/212 (10%)
Query: 319 LCSSVFVSKVKPTFESLNNGDCFILDVDHQI-FVFVGEKAKGVERMKAITVANQIKDQDH 377
L S + +V SLN+ D F+L + +++VG+ A E A VA+ +K +
Sbjct: 519 LASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKT- 577
Query: 378 NGRADIEVVDSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISD 437
+ + + E + F+++LG + E + R L S+
Sbjct: 578 -----LRIQEGEEPE----EFWNSLGGKKDYQTSPLLETQAEDHPPR-------LYGCSN 621
Query: 438 KTGSIRITRLPAPLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLK 497
KTG I +P ++ L D+ +LD ++ I++W+G+ +N EK E++ A+ YL+
Sbjct: 622 KTGRFVIEEIPGEFTQDDLAEDDVMLLD--AWEQIFIWIGKDANEVEKKESLKSAKMYLE 679
Query: 498 Y--HDYPAWVHVSKVPEGAEPIPFKQYFEDWN 527
+ + +G EP F +F W+
Sbjct: 680 TDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWD 711
Score = 44.0 bits (99), Expect = 0.001
Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 3/101 (2%)
Query: 416 GGDDQEFERVVTKEVSLSEISDKTGSIRITRLPAPLKKEQLNTDECYVLDTGSYSGIYVW 475
GG V+T +++ + G + PL + N +C+++D G + IY W
Sbjct: 120 GGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLG--TEIYQW 177
Query: 476 VGRGSNLKEKAEAMNRAEQYLKYHDYPAWVHVSKVPEGAEP 516
G N E+ +A N+ ++Y++ + V EG+EP
Sbjct: 178 CGSSCNKYERLKA-NQVATGIRYNERKGRSELIVVEEGSEP 217
Score = 42.7 bits (96), Expect = 0.003
Identities = 19/39 (48%), Positives = 26/39 (66%)
Query: 150 IRYLKGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQV 188
++Y GG ASG +HV N+ T KRL +KG+R VR +V
Sbjct: 115 LKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEV 153
>AK075123-1|BAC11416.1| 715|Homo sapiens protein ( Homo sapiens
cDNA FLJ90642 fis, clone PLACE1004078, highly similar to
Bovine mRNA for adseverin. ).
Length = 715
Score = 119 bits (287), Expect = 2e-26
Identities = 67/208 (32%), Positives = 113/208 (54%), Gaps = 12/208 (5%)
Query: 323 VFVSKVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRAD 382
V ++V +++S N GDCFI+D+ +I+ + G ER+KA VA I+ + GR++
Sbjct: 148 VRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKGRSE 207
Query: 383 IEVVDSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVT--KEVSLSEISDKTG 440
+ VV+ + + G K + D GGDD + ++ K L +SD +G
Sbjct: 208 LIVVEEGSEPSELIKVL-----GEKPELPD---GGDDDDIIADISNRKMAKLYMVSDASG 259
Query: 441 SIRITRLPA--PLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKY 498
S+R+T + P L ++EC++LD G+ I+VW G+ +N +E+ AM AE++L+
Sbjct: 260 SMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQ 319
Query: 499 HDYPAWVHVSKVPEGAEPIPFKQYFEDW 526
+Y + +PEG E FKQ+F+DW
Sbjct: 320 MNYSKNTQIQVLPEGGETPIFKQFFKDW 347
Score = 115 bits (276), Expect = 5e-25
Identities = 53/106 (50%), Positives = 72/106 (67%), Gaps = 1/106 (0%)
Query: 5 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 64
H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y++L+T T+ +HFWL
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLMLHTAKTSRGFTYHLHFWL 66
Query: 65 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
G SQDE+ AAAI TV +DD G VQ+RE+Q YES +F+ YF
Sbjct: 67 GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYF 111
Score = 60.1 bits (139), Expect = 2e-08
Identities = 40/110 (36%), Positives = 54/110 (49%), Gaps = 7/110 (6%)
Query: 1 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 60
M H D K +EIWR+EN + V + +G FY GD YI+L T + ++ I
Sbjct: 384 MAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI---I 437
Query: 61 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
+ W G+ ++DE +A LTV L D G AVQ R Q E L F
Sbjct: 438 YTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLF 486
Score = 50.4 bits (115), Expect = 2e-05
Identities = 50/212 (23%), Positives = 93/212 (43%), Gaps = 22/212 (10%)
Query: 319 LCSSVFVSKVKPTFESLNNGDCFILDVDHQI-FVFVGEKAKGVERMKAITVANQIKDQDH 377
L S + +V SLN+ D F+L + +++VG+ A E A VA+ +K +
Sbjct: 519 LASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKT- 577
Query: 378 NGRADIEVVDSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISD 437
+ + + E + F+++LG + E + R L S+
Sbjct: 578 -----LRIQEGEEPE----EFWNSLGGKKDYQTSPLLETQAEDHPPR-------LYGCSN 621
Query: 438 KTGSIRITRLPAPLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLK 497
KTG I +P ++ L D+ +LD ++ I++W+G+ +N EK E++ A+ YL+
Sbjct: 622 KTGRFVIEEIPGEFTQDDLAEDDVMLLD--AWEQIFIWIGKDANEVEKKESLKSAKMYLE 679
Query: 498 Y--HDYPAWVHVSKVPEGAEPIPFKQYFEDWN 527
+ + +G EP F +F W+
Sbjct: 680 TDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWD 711
Score = 44.0 bits (99), Expect = 0.001
Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 3/101 (2%)
Query: 416 GGDDQEFERVVTKEVSLSEISDKTGSIRITRLPAPLKKEQLNTDECYVLDTGSYSGIYVW 475
GG V+T +++ + G + PL + N +C+++D G + IY W
Sbjct: 120 GGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLG--TEIYQW 177
Query: 476 VGRGSNLKEKAEAMNRAEQYLKYHDYPAWVHVSKVPEGAEP 516
G N E+ +A N+ ++Y++ + V EG+EP
Sbjct: 178 CGSSCNKYERLKA-NQVATGIRYNERKGRSELIVVEEGSEP 217
Score = 42.7 bits (96), Expect = 0.003
Identities = 19/39 (48%), Positives = 26/39 (66%)
Query: 150 IRYLKGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQV 188
++Y GG ASG +HV N+ T KRL +KG+R VR +V
Sbjct: 115 LKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEV 153
>AF276507-1|AAK60494.1| 715|Homo sapiens scinderin protein.
Length = 715
Score = 119 bits (287), Expect = 2e-26
Identities = 67/208 (32%), Positives = 113/208 (54%), Gaps = 12/208 (5%)
Query: 323 VFVSKVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRAD 382
V ++V +++S N GDCFI+D+ +I+ + G ER+KA VA I+ + GR++
Sbjct: 148 VRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKGRSE 207
Query: 383 IEVVDSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVT--KEVSLSEISDKTG 440
+ VV+ + + G K + D GGDD + ++ K L +SD +G
Sbjct: 208 LIVVEEGSEPSELIKVL-----GEKPELPD---GGDDDDIIADISNRKMAKLYMVSDASG 259
Query: 441 SIRITRLPA--PLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKY 498
S+R+T + P L ++EC++LD G+ I+VW G+ +N +E+ AM AE++L+
Sbjct: 260 SMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQ 319
Query: 499 HDYPAWVHVSKVPEGAEPIPFKQYFEDW 526
+Y + +PEG E FKQ+F+DW
Sbjct: 320 MNYSKNTQIQVLPEGGETPIFKQFFKDW 347
Score = 116 bits (279), Expect = 2e-25
Identities = 54/106 (50%), Positives = 72/106 (67%), Gaps = 1/106 (0%)
Query: 5 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 64
H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y+VL+T T+ +HFWL
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 66
Query: 65 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
G SQDE+ AAAI TV +DD G VQ+RE+Q YES +F+ YF
Sbjct: 67 GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYF 111
Score = 60.1 bits (139), Expect = 2e-08
Identities = 40/110 (36%), Positives = 54/110 (49%), Gaps = 7/110 (6%)
Query: 1 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 60
M H D K +EIWR+EN + V + +G FY GD YI+L T + ++ I
Sbjct: 384 MAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI---I 437
Query: 61 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
+ W G+ ++DE +A LTV L D G AVQ R Q E L F
Sbjct: 438 YTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQDKEPVHLLSLF 486
Score = 50.8 bits (116), Expect = 1e-05
Identities = 50/212 (23%), Positives = 93/212 (43%), Gaps = 22/212 (10%)
Query: 319 LCSSVFVSKVKPTFESLNNGDCFILDVDHQI-FVFVGEKAKGVERMKAITVANQIKDQDH 377
L S + +V SLN+ D F+L + +++VG+ A E A VA+ +K +
Sbjct: 519 LASITRIVEVDVDANSLNSNDVFVLKLSQNSGYIWVGKGASQEEEKGAEYVASVLKCKT- 577
Query: 378 NGRADIEVVDSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISD 437
+ + + E + F+++LG + E + R L S+
Sbjct: 578 -----LRIQEGEEPE----EFWNSLGGKKDYQTSPLLETQAEDHPPR-------LYGCSN 621
Query: 438 KTGSIRITRLPAPLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLK 497
KTG I +P ++ L D+ +LD ++ I++W+G+ +N EK E++ A+ YL+
Sbjct: 622 KTGRFVIEEIPGEFTQDDLAEDDVMLLD--AWEQIFIWIGKDANEVEKKESLKSAKMYLE 679
Query: 498 Y--HDYPAWVHVSKVPEGAEPIPFKQYFEDWN 527
+ + +G EP F +F W+
Sbjct: 680 TDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWD 711
Score = 44.0 bits (99), Expect = 0.001
Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 3/101 (2%)
Query: 416 GGDDQEFERVVTKEVSLSEISDKTGSIRITRLPAPLKKEQLNTDECYVLDTGSYSGIYVW 475
GG V+T +++ + G + PL + N +C+++D G + IY W
Sbjct: 120 GGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLG--TEIYQW 177
Query: 476 VGRGSNLKEKAEAMNRAEQYLKYHDYPAWVHVSKVPEGAEP 516
G N E+ +A N+ ++Y++ + V EG+EP
Sbjct: 178 CGSSCNKYERLKA-NQVATGIRYNERKGRSELIVVEEGSEP 217
Score = 42.7 bits (96), Expect = 0.003
Identities = 19/39 (48%), Positives = 26/39 (66%)
Query: 150 IRYLKGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQV 188
++Y GG ASG +HV N+ T KRL +KG+R VR +V
Sbjct: 115 LKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEV 153
>AC005281-1|AAD15423.1| 527|Homo sapiens WUGSC:H_DJ0722F20.1
protein.
Length = 527
Score = 119 bits (287), Expect = 2e-26
Identities = 67/208 (32%), Positives = 113/208 (54%), Gaps = 12/208 (5%)
Query: 323 VFVSKVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRAD 382
V ++V +++S N GDCFI+D+ +I+ + G ER+KA VA I+ + GR++
Sbjct: 148 VRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKGRSE 207
Query: 383 IEVVDSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVT--KEVSLSEISDKTG 440
+ VV+ + + G K + D GGDD + ++ K L +SD +G
Sbjct: 208 LIVVEEGSEPSELIKVL-----GEKPELPD---GGDDDDIIADISNRKMAKLYMVSDASG 259
Query: 441 SIRITRLPA--PLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKY 498
S+R+T + P L ++EC++LD G+ I+VW G+ +N +E+ AM AE++L+
Sbjct: 260 SMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQ 319
Query: 499 HDYPAWVHVSKVPEGAEPIPFKQYFEDW 526
+Y + +PEG E FKQ+F+DW
Sbjct: 320 MNYSKNTQIQVLPEGGETPIFKQFFKDW 347
Score = 116 bits (279), Expect = 2e-25
Identities = 54/106 (50%), Positives = 72/106 (67%), Gaps = 1/106 (0%)
Query: 5 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 64
H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y+VL+T T+ +HFWL
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 66
Query: 65 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
G SQDE+ AAAI TV +DD G VQ+RE+Q YES +F+ YF
Sbjct: 67 GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYF 111
Score = 60.1 bits (139), Expect = 2e-08
Identities = 40/110 (36%), Positives = 54/110 (49%), Gaps = 7/110 (6%)
Query: 1 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 60
M H D K +EIWR+EN + V + +G FY GD YI+L T + ++ I
Sbjct: 384 MAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI---I 437
Query: 61 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
+ W G+ ++DE +A LTV L D G AVQ R Q E L F
Sbjct: 438 YTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLF 486
Score = 44.0 bits (99), Expect = 0.001
Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 3/101 (2%)
Query: 416 GGDDQEFERVVTKEVSLSEISDKTGSIRITRLPAPLKKEQLNTDECYVLDTGSYSGIYVW 475
GG V+T +++ + G + PL + N +C+++D G + IY W
Sbjct: 120 GGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLG--TEIYQW 177
Query: 476 VGRGSNLKEKAEAMNRAEQYLKYHDYPAWVHVSKVPEGAEP 516
G N E+ +A N+ ++Y++ + V EG+EP
Sbjct: 178 CGSSCNKYERLKA-NQVATGIRYNERKGRSELIVVEEGSEP 217
Score = 42.7 bits (96), Expect = 0.003
Identities = 19/39 (48%), Positives = 26/39 (66%)
Query: 150 IRYLKGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQV 188
++Y GG ASG +HV N+ T KRL +KG+R VR +V
Sbjct: 115 LKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEV 153
>AB067492-1|BAB67798.1| 626|Homo sapiens KIAA1905 protein protein.
Length = 626
Score = 119 bits (287), Expect = 2e-26
Identities = 67/208 (32%), Positives = 113/208 (54%), Gaps = 12/208 (5%)
Query: 323 VFVSKVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRAD 382
V ++V +++S N GDCFI+D+ +I+ + G ER+KA VA I+ + GR++
Sbjct: 194 VRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKGRSE 253
Query: 383 IEVVDSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVT--KEVSLSEISDKTG 440
+ VV+ + + G K + D GGDD + ++ K L +SD +G
Sbjct: 254 LIVVEEGSEPSELIKVL-----GEKPELPD---GGDDDDIIADISNRKMAKLYMVSDASG 305
Query: 441 SIRITRLPA--PLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKY 498
S+R+T + P L ++EC++LD G+ I+VW G+ +N +E+ AM AE++L+
Sbjct: 306 SMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQ 365
Query: 499 HDYPAWVHVSKVPEGAEPIPFKQYFEDW 526
+Y + +PEG E FKQ+F+DW
Sbjct: 366 MNYSKNTQIQVLPEGGETPIFKQFFKDW 393
Score = 116 bits (279), Expect = 2e-25
Identities = 54/106 (50%), Positives = 72/106 (67%), Gaps = 1/106 (0%)
Query: 5 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 64
H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y+VL+T T+ +HFWL
Sbjct: 53 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 112
Query: 65 GSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
G SQDE+ AAAI TV +DD G VQ+RE+Q YES +F+ YF
Sbjct: 113 GKECSQDESTAAAIFTVQMDD-YLGGKPVQNRELQGYESNDFVSYF 157
Score = 60.1 bits (139), Expect = 2e-08
Identities = 40/110 (36%), Positives = 54/110 (49%), Gaps = 7/110 (6%)
Query: 1 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 60
M H D K +EIWR+EN + V + +G FY GD YI+L T + ++ I
Sbjct: 430 MAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI---I 483
Query: 61 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
+ W G+ ++DE +A LTV L D G AVQ R Q E L F
Sbjct: 484 YTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLF 532
Score = 44.0 bits (99), Expect = 0.001
Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 3/101 (2%)
Query: 416 GGDDQEFERVVTKEVSLSEISDKTGSIRITRLPAPLKKEQLNTDECYVLDTGSYSGIYVW 475
GG V+T +++ + G + PL + N +C+++D G + IY W
Sbjct: 166 GGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLG--TEIYQW 223
Query: 476 VGRGSNLKEKAEAMNRAEQYLKYHDYPAWVHVSKVPEGAEP 516
G N E+ +A N+ ++Y++ + V EG+EP
Sbjct: 224 CGSSCNKYERLKA-NQVATGIRYNERKGRSELIVVEEGSEP 263
Score = 42.7 bits (96), Expect = 0.003
Identities = 19/39 (48%), Positives = 26/39 (66%)
Query: 150 IRYLKGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQV 188
++Y GG ASG +HV N+ T KRL +KG+R VR +V
Sbjct: 161 LKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEV 199
>M94345-1|AAA59570.1| 348|Homo sapiens macrophage capping protein
protein.
Length = 348
Score = 119 bits (286), Expect = 3e-26
Identities = 66/197 (33%), Positives = 105/197 (53%), Gaps = 8/197 (4%)
Query: 332 FESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVVDSEAH 391
++S N GDCFILD+ IF + G K+ +ER KA +A I+D + G+A +E+V
Sbjct: 157 WDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEE 216
Query: 392 DGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIRITRLP--A 449
LG K A+ + +D ++ + +L ++SD TG + +T++ +
Sbjct: 217 PA---EMIQVLGP--KPALKEGNPE-EDLTADKANAQAAALYKVSDATGQMNLTKVADSS 270
Query: 450 PLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKYHDYPAWVHVSK 509
P E L +D+C+VLD G IY+W GR +N KE+ A+ AE ++ Y V
Sbjct: 271 PFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEI 330
Query: 510 VPEGAEPIPFKQYFEDW 526
+P+G E FKQ+F+DW
Sbjct: 331 LPQGRESPIFKQFFKDW 347
Score = 88.6 bits (210), Expect = 5e-17
Identities = 44/110 (40%), Positives = 67/110 (60%), Gaps = 4/110 (3%)
Query: 1 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 60
+P+ F + + PGL +WR+E +PV V + G+F+SGDSY+VL+ ++ +
Sbjct: 5 IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61
Query: 61 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
H W+G ++S+DE GA A+L V+L + VQHREVQ ES F+ YF
Sbjct: 62 HLWIGQQSSRDEQGACAVLAVHL-NTLLGERPVQHREVQGNESDLFMSYF 110
Score = 41.9 bits (94), Expect = 0.005
Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 4/104 (3%)
Query: 414 EEGGDDQEFERVVT-KEVSLSEISDKTGSIRITRLPAPLKKEQLNTDECYVLDTGSYSGI 472
+EGG + F + T ++ ++ G I L + NT +C++LD G I
Sbjct: 117 QEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLG--QNI 174
Query: 473 YVWVGRGSNLKEKAEAMNRAEQYLKYHDYPAWVHVSKVPEGAEP 516
+ W G SN+ E+ +A + A ++ + V V +G EP
Sbjct: 175 FAWCGGKSNILERNKARDLA-LAIRDSERQGKAQVEIVTDGEEP 217
Score = 31.9 bits (69), Expect = 5.7
Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 2/48 (4%)
Query: 142 LIRETFP-AIRYLKGGHASGFSHVTINEGTE-KRLFQIKGKRNVRVKQ 187
L FP ++Y +GG S F + K+L+Q+KGK+N+R +
Sbjct: 105 LFMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATE 152
>BC014549-1|AAH14549.1| 348|Homo sapiens capping protein (actin
filament), gelsolin-like protein.
Length = 348
Score = 119 bits (286), Expect = 3e-26
Identities = 66/197 (33%), Positives = 105/197 (53%), Gaps = 8/197 (4%)
Query: 332 FESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVVDSEAH 391
++S N GDCFILD+ IF + G K+ +ER KA +A I+D + G+A +E+V
Sbjct: 157 WDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEE 216
Query: 392 DGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIRITRLP--A 449
LG K A+ + +D ++ + +L ++SD TG + +T++ +
Sbjct: 217 PA---EMIQVLGP--KPALKEGNPE-EDLTADKANAQAAALYKVSDATGQMNLTKVADSS 270
Query: 450 PLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKYHDYPAWVHVSK 509
P E L +D+C+VLD G IY+W GR +N KE+ A+ AE ++ Y V
Sbjct: 271 PFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEI 330
Query: 510 VPEGAEPIPFKQYFEDW 526
+P+G E FKQ+F+DW
Sbjct: 331 LPQGRESPIFKQFFKDW 347
Score = 88.6 bits (210), Expect = 5e-17
Identities = 44/110 (40%), Positives = 67/110 (60%), Gaps = 4/110 (3%)
Query: 1 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 60
+P+ F + + PGL +WR+E +PV V + G+F+SGDSY+VL+ ++ +
Sbjct: 5 IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61
Query: 61 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
H W+G ++S+DE GA A+L V+L + VQHREVQ ES F+ YF
Sbjct: 62 HLWIGQQSSRDEQGACAVLAVHL-NTLLGERPVQHREVQGNESDLFMSYF 110
Score = 41.9 bits (94), Expect = 0.005
Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 4/104 (3%)
Query: 414 EEGGDDQEFERVVT-KEVSLSEISDKTGSIRITRLPAPLKKEQLNTDECYVLDTGSYSGI 472
+EGG + F + T ++ ++ G I L + NT +C++LD G I
Sbjct: 117 QEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLG--QNI 174
Query: 473 YVWVGRGSNLKEKAEAMNRAEQYLKYHDYPAWVHVSKVPEGAEP 516
+ W G SN+ E+ +A + A ++ + V V +G EP
Sbjct: 175 FAWCGGKSNILERNKARDLA-LAIRDSERQGKAQVEIVTDGEEP 217
Score = 31.9 bits (69), Expect = 5.7
Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 2/48 (4%)
Query: 142 LIRETFP-AIRYLKGGHASGFSHVTINEGTE-KRLFQIKGKRNVRVKQ 187
L FP ++Y +GG S F + K+L+Q+KGK+N+R +
Sbjct: 105 LFMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATE 152
>BC000728-1|AAH00728.1| 348|Homo sapiens capping protein (actin
filament), gelsolin-like protein.
Length = 348
Score = 119 bits (286), Expect = 3e-26
Identities = 66/197 (33%), Positives = 105/197 (53%), Gaps = 8/197 (4%)
Query: 332 FESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVVDSEAH 391
++S N GDCFILD+ IF + G K+ +ER KA +A I+D + G+A +E+V
Sbjct: 157 WDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEE 216
Query: 392 DGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIRITRLP--A 449
LG K A+ + +D ++ + +L ++SD TG + +T++ +
Sbjct: 217 PA---EMIQVLGP--KPALKEGNPE-EDLTADKANAQAAALYKVSDATGQMNLTKVADSS 270
Query: 450 PLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKYHDYPAWVHVSK 509
P E L +D+C+VLD G IY+W GR +N KE+ A+ AE ++ Y V
Sbjct: 271 PFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEI 330
Query: 510 VPEGAEPIPFKQYFEDW 526
+P+G E FKQ+F+DW
Sbjct: 331 LPQGRESPIFKQFFKDW 347
Score = 88.6 bits (210), Expect = 5e-17
Identities = 44/110 (40%), Positives = 67/110 (60%), Gaps = 4/110 (3%)
Query: 1 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 60
+P+ F + + PGL +WR+E +PV V + G+F+SGDSY+VL+ ++ +
Sbjct: 5 IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61
Query: 61 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
H W+G ++S+DE GA A+L V+L + VQHREVQ ES F+ YF
Sbjct: 62 HLWIGQQSSRDEQGACAVLAVHL-NTLLGERPVQHREVQGNESDLFMSYF 110
Score = 41.9 bits (94), Expect = 0.005
Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 4/104 (3%)
Query: 414 EEGGDDQEFERVVT-KEVSLSEISDKTGSIRITRLPAPLKKEQLNTDECYVLDTGSYSGI 472
+EGG + F + T ++ ++ G I L + NT +C++LD G I
Sbjct: 117 QEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLG--QNI 174
Query: 473 YVWVGRGSNLKEKAEAMNRAEQYLKYHDYPAWVHVSKVPEGAEP 516
+ W G SN+ E+ +A + A ++ + V V +G EP
Sbjct: 175 FAWCGGKSNILERNKARDLA-LAIRDSERQGKAQVEIVTDGEEP 217
Score = 31.9 bits (69), Expect = 5.7
Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 2/48 (4%)
Query: 142 LIRETFP-AIRYLKGGHASGFSHVTINEGTE-KRLFQIKGKRNVRVKQ 187
L FP ++Y +GG S F + K+L+Q+KGK+N+R +
Sbjct: 105 LFMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATE 152
>AC062037-3|AAY24128.1| 348|Homo sapiens unknown protein.
Length = 348
Score = 118 bits (285), Expect = 4e-26
Identities = 66/197 (33%), Positives = 105/197 (53%), Gaps = 8/197 (4%)
Query: 332 FESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVVDSEAH 391
++S N GDCFILD+ IF + G K+ +ER KA +A I+D + G+A +E+V
Sbjct: 157 WDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEE 216
Query: 392 DGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIRITRLP--A 449
LG K A+ + +D ++ + +L ++SD TG + +T++ +
Sbjct: 217 PA---EMIQVLGP--KPALKEGNPE-EDLTADKANAQAAALYKVSDATGQMNLTKVADSS 270
Query: 450 PLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKYHDYPAWVHVSK 509
P E L +D+C+VLD G IY+W GR +N KE+ A+ AE ++ Y V
Sbjct: 271 PFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEI 330
Query: 510 VPEGAEPIPFKQYFEDW 526
+P+G E FKQ+F+DW
Sbjct: 331 LPQGHESPIFKQFFKDW 347
Score = 88.6 bits (210), Expect = 5e-17
Identities = 44/110 (40%), Positives = 67/110 (60%), Gaps = 4/110 (3%)
Query: 1 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 60
+P+ F + + PGL +WR+E +PV V + G+F+SGDSY+VL+ ++ +
Sbjct: 5 IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61
Query: 61 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
H W+G ++S+DE GA A+L V+L + VQHREVQ ES F+ YF
Sbjct: 62 HLWIGQQSSRDEQGACAVLAVHL-NTLLGERPVQHREVQGNESDLFMSYF 110
Score = 41.9 bits (94), Expect = 0.005
Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 4/104 (3%)
Query: 414 EEGGDDQEFERVVT-KEVSLSEISDKTGSIRITRLPAPLKKEQLNTDECYVLDTGSYSGI 472
+EGG + F + T ++ ++ G I L + NT +C++LD G I
Sbjct: 117 QEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLG--QNI 174
Query: 473 YVWVGRGSNLKEKAEAMNRAEQYLKYHDYPAWVHVSKVPEGAEP 516
+ W G SN+ E+ +A + A ++ + V V +G EP
Sbjct: 175 FAWCGGKSNILERNKARDLA-LAIRDSERQGKAQVEIVTDGEEP 217
Score = 31.9 bits (69), Expect = 5.7
Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 2/48 (4%)
Query: 142 LIRETFP-AIRYLKGGHASGFSHVTINEGTE-KRLFQIKGKRNVRVKQ 187
L FP ++Y +GG S F + K+L+Q+KGK+N+R +
Sbjct: 105 LFMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATE 152
>BC111730-1|AAI11731.1| 812|Homo sapiens AVIL protein protein.
Length = 812
Score = 118 bits (284), Expect = 5e-26
Identities = 68/210 (32%), Positives = 117/210 (55%), Gaps = 10/210 (4%)
Query: 322 SVFVSKVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRA 381
++ ++V+ +++S N GD F+LD+ I + G ++ ER+KA+ +A I+D++ GRA
Sbjct: 137 NIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRA 196
Query: 382 DIEVVDSE---AHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDK 438
+I V++ + A + D LG + +I D+ ++ + L ISD
Sbjct: 197 EIGVIEGDKEAASPELMKVLQDTLG---RRSIIKPTV--PDEIIDQKQKSTIMLYHISDS 251
Query: 439 TGSIRITRLPA-PLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLK 497
G + +T + PL ++ LN D+CY+LD S + IYVW G+G+ EK AM++A ++K
Sbjct: 252 AGQLAVTEVATRPLVQDLLNHDDCYILDQ-SGTKIYVWKGKGATKAEKQAAMSKALGFIK 310
Query: 498 YHDYPAWVHVSKVPEGAEPIPFKQYFEDWN 527
YP+ +V V +GAE FKQ F+ W+
Sbjct: 311 MKSYPSSTNVETVNDGAESAMFKQLFQKWS 340
Score = 92.3 bits (219), Expect = 4e-18
Identities = 48/102 (47%), Positives = 58/102 (56%), Gaps = 2/102 (1%)
Query: 9 ADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRT 68
+ G +IW E E VP + G FY GD Y++L+T L+ DIHFW+G +
Sbjct: 2 SSTGHPGSYKIWG-EKMELALVPVSAHGNFYEGDCYVILSTRRVASLLSQDIHFWIGKDS 60
Query: 69 SQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
SQDE AAI T LDD GS VQHREVQY+ES F YF
Sbjct: 61 SQDEQSCAAIYTTQLDD-YLGGSPVQHREVQYHESDTFRGYF 101
Score = 70.1 bits (164), Expect = 2e-11
Identities = 38/94 (40%), Positives = 50/94 (53%), Gaps = 1/94 (1%)
Query: 17 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAA 76
+E+WRIEN E V V +G FY GD Y+VL T + ++ W G SQDE A+
Sbjct: 390 VEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVNGKPHHILYIWQGRHASQDELAAS 449
Query: 77 AILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
A V + D QF G+AVQ R E + F+ F
Sbjct: 450 AYQAVEV-DRQFDGAAVQVRVRMGTEPRHFMAIF 482
Score = 61.3 bits (142), Expect = 8e-09
Identities = 54/203 (26%), Positives = 95/203 (46%), Gaps = 26/203 (12%)
Query: 330 PTF-ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVVDS 388
P F SLN+ D F+L + +++ G+ + G ER A +A+ + D N A+
Sbjct: 524 PAFASSLNSNDVFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCDGSENTVAE----GQ 579
Query: 389 EAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIRITRLP 448
E + F+D LG A D + + ++ + L E S+KTG +T +
Sbjct: 580 EPAE-----FWDLLGGKTPYA-------NDKRLQQEILDVQSRLFECSNKTGQFVVTEI- 626
Query: 449 APLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKYHDYPAW---- 504
++ LN + +LDT + +++W+G +N EK A+ A+QYL H +P+
Sbjct: 627 TDFTQDDLNPTDVMLLDT--WDQVFLWIGAEANATEKESALATAQQYL--HTHPSGRDPD 682
Query: 505 VHVSKVPEGAEPIPFKQYFEDWN 527
+ + +G EP F +F W+
Sbjct: 683 TPILIIKQGFEPPIFTGWFLAWD 705
Score = 42.7 bits (96), Expect = 0.003
Identities = 20/39 (51%), Positives = 24/39 (61%)
Query: 150 IRYLKGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQV 188
I Y +GG ASG HV N KRL +KGKRN+R +V
Sbjct: 105 IIYKQGGVASGMKHVETNTYDVKRLLHVKGKRNIRATEV 143
>AF041449-1|AAC25051.1| 819|Homo sapiens advillin protein.
Length = 819
Score = 118 bits (284), Expect = 5e-26
Identities = 68/210 (32%), Positives = 117/210 (55%), Gaps = 10/210 (4%)
Query: 322 SVFVSKVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRA 381
++ ++V+ +++S N GD F+LD+ I + G ++ ER+KA+ +A I+D++ GRA
Sbjct: 144 NIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRA 203
Query: 382 DIEVVDSE---AHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDK 438
+I V++ + A + D LG + +I D+ ++ + L ISD
Sbjct: 204 EIGVIEGDKEAASPELMKVLQDTLG---RRSIIKPTV--PDEIIDQKQKSTIMLYHISDS 258
Query: 439 TGSIRITRLPA-PLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLK 497
G + +T + PL ++ LN D+CY+LD S + IYVW G+G+ EK AM++A ++K
Sbjct: 259 AGQLAVTEVATRPLVQDLLNHDDCYILDQ-SGTKIYVWKGKGATKAEKQAAMSKALGFIK 317
Query: 498 YHDYPAWVHVSKVPEGAEPIPFKQYFEDWN 527
YP+ +V V +GAE FKQ F+ W+
Sbjct: 318 MKSYPSSTNVETVNDGAESAMFKQLFQKWS 347
Score = 105 bits (253), Expect = 3e-22
Identities = 52/104 (50%), Positives = 62/104 (59%), Gaps = 1/104 (0%)
Query: 7 AFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGS 66
AF PG+ +WRIE E VP + G FY GD Y++L+T L+ DIHFW+G
Sbjct: 6 AFRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVASLLSQDIHFWIGK 65
Query: 67 RTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
+SQDE AAI T LDD GS VQHREVQY+ES F YF
Sbjct: 66 DSSQDEQSCAAIYTTQLDD-YLGGSPVQHREVQYHESDTFRGYF 108
Score = 67.3 bits (157), Expect = 1e-10
Identities = 37/94 (39%), Positives = 49/94 (52%), Gaps = 1/94 (1%)
Query: 17 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAA 76
+E+WRIEN E V V +G FY GD Y+VL T + ++ W SQDE A+
Sbjct: 397 VEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVNGKPHHILYIWQDRHASQDELAAS 456
Query: 77 AILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
A V + D QF G+AVQ R E + F+ F
Sbjct: 457 AYQAVEV-DRQFDGAAVQVRVRMGTEPRHFMAIF 489
Score = 61.3 bits (142), Expect = 8e-09
Identities = 54/203 (26%), Positives = 95/203 (46%), Gaps = 26/203 (12%)
Query: 330 PTF-ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVVDS 388
P F SLN+ D F+L + +++ G+ + G ER A +A+ + D N A+
Sbjct: 531 PAFASSLNSNDVFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCDGSENTVAE----GQ 586
Query: 389 EAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIRITRLP 448
E + F+D LG A D + + ++ + L E S+KTG +T +
Sbjct: 587 EPAE-----FWDLLGGKTPYA-------NDKRLQQEILDVQSRLFECSNKTGQFVVTEI- 633
Query: 449 APLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKYHDYPAW---- 504
++ LN + +LDT + +++W+G +N EK A+ A+QYL H +P+
Sbjct: 634 TDFTQDDLNPTDVMLLDT--WDQVFLWIGAEANATEKESALATAQQYL--HTHPSGRDPD 689
Query: 505 VHVSKVPEGAEPIPFKQYFEDWN 527
+ + +G EP F +F W+
Sbjct: 690 TPILIIKQGFEPPIFTGWFLAWD 712
Score = 42.7 bits (96), Expect = 0.003
Identities = 20/39 (51%), Positives = 24/39 (61%)
Query: 150 IRYLKGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQV 188
I Y +GG ASG HV N KRL +KGKRN+R +V
Sbjct: 112 IIYKQGGVASGMKHVETNTYDVKRLLHVKGKRNIRATEV 150
>X12901-1|CAA31386.1| 827|Homo sapiens protein ( Human mRNA for
villin. ).
Length = 827
Score = 108 bits (259), Expect = 5e-23
Identities = 63/209 (30%), Positives = 109/209 (52%), Gaps = 10/209 (4%)
Query: 322 SVFVSKVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRA 381
+V +V+ +++S N GD F+LD+ I + G ++ +ER++ +T+A +I+DQ+ GR
Sbjct: 147 NVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAKEIRDQERGGRT 206
Query: 382 DIEVVDSE---AHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDK 438
+ VVD E A + + LG + + D E + + L +SD
Sbjct: 207 YVGVVDGENELASPKLMEVMNHVLGKRR-----ELKAAVPDTVVEPALKAALKLYHVSDS 261
Query: 439 TGSIRITRLPA-PLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLK 497
G++ + + PL ++ L+ ++CY+LD G IYVW G+ +N +EK AM+ A ++K
Sbjct: 262 EGNLVVREVATRPLTQDLLSHEDCYILDQGGLK-IYVWKGKKANEQEKKGAMSHALNFIK 320
Query: 498 YHDYPAWVHVSKVPEGAEPIPFKQYFEDW 526
YP V +GAE F+Q F+ W
Sbjct: 321 AKQYPPSTQVEVQNDGAESAVFQQLFQKW 349
Score = 103 bits (247), Expect = 2e-21
Identities = 50/96 (52%), Positives = 63/96 (65%), Gaps = 1/96 (1%)
Query: 15 PGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAG 74
PGL+IWRIE + V VP + FG F+ GD YI+L L++DIH+W+G +S DE G
Sbjct: 17 PGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQG 76
Query: 75 AAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
AAAI T +DD +G AVQHREVQ ES+ F YF
Sbjct: 77 AAAIYTTQMDD-FLKGRAVQHREVQGNESEAFRGYF 111
Score = 61.3 bits (142), Expect = 8e-09
Identities = 34/94 (36%), Positives = 50/94 (53%), Gaps = 1/94 (1%)
Query: 17 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAA 76
+++WRIEN E V V G FY GD Y++L T ++ + ++ W GS+ SQDE A+
Sbjct: 400 VQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTYLIGEKQHYLLYVWQGSQASQDEITAS 459
Query: 77 AILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
A V L D+++ G VQ R E + F
Sbjct: 460 AYQAVIL-DQKYNGEPVQIRVPMGKEPPHLMSIF 492
Score = 61.3 bits (142), Expect = 8e-09
Identities = 56/195 (28%), Positives = 89/195 (45%), Gaps = 21/195 (10%)
Query: 335 LNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVVDSEAHDGI 394
LN+ D F+L +++ G+ G ER A VA+ I R + +VV
Sbjct: 540 LNSNDVFVLKTQSCCYLWCGKGCSGDEREMAKMVADTIS------RTEKQVVVEGQEPA- 592
Query: 395 FDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIRITRLPAPLKKE 454
F+ ALG K A+ + QE V+T L E S+KTG T +P ++
Sbjct: 593 --NFWMALGG--KAPYANTKRL---QEENLVITPR--LFECSNKTGRFLATEIP-DFNQD 642
Query: 455 QLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKYH--DYPAWVHVSKVPE 512
L D+ ++LD + ++ W+G+ +N +EK A A++YLK H + V +
Sbjct: 643 DLEEDDVFLLDV--WDQVFFWIGKHANEEEKKAAATTAQEYLKTHPSGRDPETPIIVVKQ 700
Query: 513 GAEPIPFKQYFEDWN 527
G EP F +F W+
Sbjct: 701 GHEPPTFTGWFLAWD 715
Score = 37.5 bits (83), Expect = 0.12
Identities = 18/35 (51%), Positives = 21/35 (60%)
Query: 154 KGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQV 188
KGG ASG HV N +RL +KGKRNV +V
Sbjct: 119 KGGVASGMKHVETNSYDVQRLLHVKGKRNVVAGEV 153
Score = 35.9 bits (79), Expect = 0.35
Identities = 34/137 (24%), Positives = 62/137 (45%), Gaps = 10/137 (7%)
Query: 324 FVSKVKPTF--ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR- 380
F++ P F + L D F+LDV Q+F ++G+ A E+ A T A + +GR
Sbjct: 631 FLATEIPDFNQDDLEEDDVFLLDVWDQVFFWIGKHANEEEKKAAATTAQEYLKTHPSGRD 690
Query: 381 --ADIEVVDSEAHDGIFDRFF---DALGSGNKEAIADAE-EGGDDQEFERVVTKEVSLSE 434
I VV F +F D N ++ D + E G+ +++ + +T EV+ +
Sbjct: 691 PETPIIVVKQGHEPPTFTGWFLAWDPFKWSNTKSYEDLKAESGNLRDWSQ-ITAEVTSPK 749
Query: 435 ISDKTGSIRITRLPAPL 451
+ + ++ P P+
Sbjct: 750 VDVFNANSNLSSGPLPI 766
>BC017303-1|AAH17303.1| 421|Homo sapiens VIL1 protein protein.
Length = 421
Score = 108 bits (259), Expect = 5e-23
Identities = 63/209 (30%), Positives = 109/209 (52%), Gaps = 10/209 (4%)
Query: 322 SVFVSKVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRA 381
+V +V+ +++S N GD F+LD+ I + G ++ +ER++ +T+A +I+DQ+ GR
Sbjct: 147 NVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAKEIRDQERGGRT 206
Query: 382 DIEVVDSE---AHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDK 438
+ VVD E A + + LG + + D E + + L +SD
Sbjct: 207 YVGVVDGENELASPKLMEVMNHVLGKRR-----ELKAAVPDTVVEPALKAALKLYHVSDS 261
Query: 439 TGSIRITRLPA-PLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLK 497
G++ + + PL ++ L+ ++CY+LD G IYVW G+ +N +EK AM+ A ++K
Sbjct: 262 EGNLVVREVATRPLTQDLLSHEDCYILDQGGLK-IYVWKGKKANEQEKKGAMSHALNFIK 320
Query: 498 YHDYPAWVHVSKVPEGAEPIPFKQYFEDW 526
YP V +GAE F+Q F+ W
Sbjct: 321 AKQYPPSTQVEVQNDGAESAVFQQLFQKW 349
Score = 103 bits (247), Expect = 2e-21
Identities = 50/96 (52%), Positives = 63/96 (65%), Gaps = 1/96 (1%)
Query: 15 PGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAG 74
PGL+IWRIE + V VP + FG F+ GD YI+L L++DIH+W+G +S DE G
Sbjct: 17 PGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQG 76
Query: 75 AAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
AAAI T +DD +G AVQHREVQ ES+ F YF
Sbjct: 77 AAAIYTTQMDD-FLKGRAVQHREVQGNESEAFRGYF 111
Score = 37.5 bits (83), Expect = 0.12
Identities = 18/35 (51%), Positives = 21/35 (60%)
Query: 154 KGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQV 188
KGG ASG HV N +RL +KGKRNV +V
Sbjct: 119 KGGVASGMKHVETNSYDVQRLLHVKGKRNVVAGEV 153
>AK223398-1|BAD97118.1| 827|Homo sapiens villin 1 variant protein.
Length = 827
Score = 108 bits (259), Expect = 5e-23
Identities = 63/209 (30%), Positives = 109/209 (52%), Gaps = 10/209 (4%)
Query: 322 SVFVSKVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRA 381
+V +V+ +++S N GD F+LD+ I + G ++ +ER++ +T+A +I+DQ+ GR
Sbjct: 147 NVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAKEIRDQERGGRT 206
Query: 382 DIEVVDSE---AHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDK 438
+ VVD E A + + LG + + D E + + L +SD
Sbjct: 207 YVGVVDGENELASPKLMEVMNHVLGKRR-----ELKAAVPDTVVEPALKAALKLYHVSDS 261
Query: 439 TGSIRITRLPA-PLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLK 497
G++ + + PL ++ L+ ++CY+LD G IYVW G+ +N +EK AM+ A ++K
Sbjct: 262 EGNLVVREVATRPLTQDLLSHEDCYILDQGGLK-IYVWKGKKANEQEKKGAMSHALNFIK 320
Query: 498 YHDYPAWVHVSKVPEGAEPIPFKQYFEDW 526
YP V +GAE F+Q F+ W
Sbjct: 321 AKQYPPSTQVEVQNDGAESAVFQQLFQKW 349
Score = 103 bits (247), Expect = 2e-21
Identities = 50/96 (52%), Positives = 63/96 (65%), Gaps = 1/96 (1%)
Query: 15 PGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAG 74
PGL+IWRIE + V VP + FG F+ GD YI+L L++DIH+W+G +S DE G
Sbjct: 17 PGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQG 76
Query: 75 AAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
AAAI T +DD +G AVQHREVQ ES+ F YF
Sbjct: 77 AAAIYTTQMDD-FLKGRAVQHREVQGNESEAFRGYF 111
Score = 61.3 bits (142), Expect = 8e-09
Identities = 34/94 (36%), Positives = 50/94 (53%), Gaps = 1/94 (1%)
Query: 17 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAA 76
+++WRIEN E V V G FY GD Y++L T ++ + ++ W GS+ SQDE A+
Sbjct: 400 VQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTYLIGEKQHYLLYVWQGSQASQDEITAS 459
Query: 77 AILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
A V L D+++ G VQ R E + F
Sbjct: 460 AYQAVIL-DQKYNGEPVQIRVPMGKEPPHLMSIF 492
Score = 61.3 bits (142), Expect = 8e-09
Identities = 56/195 (28%), Positives = 89/195 (45%), Gaps = 21/195 (10%)
Query: 335 LNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVVDSEAHDGI 394
LN+ D F+L +++ G+ G ER A VA+ I R + +VV
Sbjct: 540 LNSNDVFVLKTQSCCYLWCGKGCSGDEREMAKMVADTIS------RTEKQVVVEGQEPA- 592
Query: 395 FDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIRITRLPAPLKKE 454
F+ ALG K A+ + QE V+T L E S+KTG T +P ++
Sbjct: 593 --NFWMALGG--KAPYANTKRL---QEENLVITPR--LFECSNKTGRFLATEIP-DFNQD 642
Query: 455 QLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKYH--DYPAWVHVSKVPE 512
L D+ ++LD + ++ W+G+ +N +EK A A++YLK H + V +
Sbjct: 643 DLEEDDVFLLDV--WDQVFFWIGKHANEEEKKAAATTAQEYLKTHPSGRDPETPIIVVKQ 700
Query: 513 GAEPIPFKQYFEDWN 527
G EP F +F W+
Sbjct: 701 GHEPPTFTGWFLAWD 715
Score = 37.5 bits (83), Expect = 0.12
Identities = 18/35 (51%), Positives = 21/35 (60%)
Query: 154 KGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQV 188
KGG ASG HV N +RL +KGKRNV +V
Sbjct: 119 KGGVASGMKHVETNSYDVQRLLHVKGKRNVVAGEV 153
Score = 35.9 bits (79), Expect = 0.35
Identities = 34/137 (24%), Positives = 62/137 (45%), Gaps = 10/137 (7%)
Query: 324 FVSKVKPTF--ESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGR- 380
F++ P F + L D F+LDV Q+F ++G+ A E+ A T A + +GR
Sbjct: 631 FLATEIPDFNQDDLEEDDVFLLDVWDQVFFWIGKHANEEEKKAAATTAQEYLKTHPSGRD 690
Query: 381 --ADIEVVDSEAHDGIFDRFF---DALGSGNKEAIADAE-EGGDDQEFERVVTKEVSLSE 434
I VV F +F D N ++ D + E G+ +++ + +T EV+ +
Sbjct: 691 PETPIIVVKQGHEPPTFTGWFLAWDPFKWSNTKSYEDLKAELGNSRDWSQ-ITAEVTSPK 749
Query: 435 ISDKTGSIRITRLPAPL 451
+ + ++ P P+
Sbjct: 750 VDVFNANSNLSSGPLPI 766
>U12026-1|AAA92670.1| 172|Homo sapiens Cap-G protein.
Length = 172
Score = 88.6 bits (210), Expect = 5e-17
Identities = 44/110 (40%), Positives = 67/110 (60%), Gaps = 4/110 (3%)
Query: 1 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 60
+P+ F + + PGL +WR+E +PV V + G+F+SGDSY+VL+ ++ +
Sbjct: 5 IPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEE---VSHL 61
Query: 61 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
H W+G ++S+DE GA A+L V+L + VQHREVQ ES F+ YF
Sbjct: 62 HLWIGQQSSRDEQGACAVLAVHL-NTLLGERPVQHREVQGNESDLFMSYF 110
Score = 31.9 bits (69), Expect = 5.7
Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 2/48 (4%)
Query: 142 LIRETFP-AIRYLKGGHASGFSHVTINEGTE-KRLFQIKGKRNVRVKQ 187
L FP ++Y +GG S F + K+L+Q+KGK+N+R +
Sbjct: 105 LFMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATE 152
>BC000243-1|AAH00243.1| 686|Homo sapiens VILL protein protein.
Length = 686
Score = 83.4 bits (197), Expect = 2e-15
Identities = 51/176 (28%), Positives = 88/176 (50%), Gaps = 6/176 (3%)
Query: 354 GEKAKGVERMKAITVANQIKDQDHNG-RADIEVVDSEAHDGIFDRFFDALGSGNKEAIAD 412
G K E+ + + + ++D++ G RA I VVD EA + +A+ ++
Sbjct: 7 GPKTSISEKARGLALTYSLRDRERGGGRAQIGVVDDEAKAPDLMQIMEAVLGRRVGSLRA 66
Query: 413 AEEGGDDQEFERVVTKEVSLSEISDKTGSIRITRLPAP-LKKEQLNTDECYVLDTGSYSG 471
A D + ++ V L + +K + + L P L ++ L ++ Y+LD G +
Sbjct: 67 ATPSKDINQLQKA---NVRLYHVYEKGKDLVVLELATPPLTQDLLQEEDFYILDQGGFK- 122
Query: 472 IYVWVGRGSNLKEKAEAMNRAEQYLKYHDYPAWVHVSKVPEGAEPIPFKQYFEDWN 527
IYVW GR S+L+E+ A +RA +++ YP + +V V +GAE FKQ F W+
Sbjct: 123 IYVWQGRMSSLQERKAAFSRAVGFIQAKGYPTYTNVEVVNDGAESAAFKQLFRTWS 178
Score = 38.3 bits (85), Expect = 0.066
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
Query: 17 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAA 76
+E+W I++ V + G +G+ Y+VL T R+ + ++ W G + + DE A
Sbjct: 223 VEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQRLGRVQYILYLWQGHQATADEIEAL 282
Query: 77 AILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
L D + G VQ E FL F
Sbjct: 283 NSNAEEL-DVMYGGVLVQEHVTMGSEPPHFLAIF 315
>D88154-1|BAA21668.1| 686|Homo sapiens villin-like protein protein.
Length = 686
Score = 83.0 bits (196), Expect = 2e-15
Identities = 51/176 (28%), Positives = 88/176 (50%), Gaps = 6/176 (3%)
Query: 354 GEKAKGVERMKAITVANQIKDQDHNG-RADIEVVDSEAHDGIFDRFFDALGSGNKEAIAD 412
G K E+ + + + ++D++ G RA I VVD EA + +A+ ++
Sbjct: 7 GPKTSISEKARGLALTYSLRDRERGGGRAQIGVVDDEAKAPDLMQIMEAVLGCRVGSLRA 66
Query: 413 AEEGGDDQEFERVVTKEVSLSEISDKTGSIRITRLPAP-LKKEQLNTDECYVLDTGSYSG 471
A D + ++ V L + +K + + L P L ++ L ++ Y+LD G +
Sbjct: 67 ATPSKDINQLQKA---NVRLYHVYEKGKDLVVLELATPPLTQDLLQEEDFYILDQGGFK- 122
Query: 472 IYVWVGRGSNLKEKAEAMNRAEQYLKYHDYPAWVHVSKVPEGAEPIPFKQYFEDWN 527
IYVW GR S+L+E+ A +RA +++ YP + +V V +GAE FKQ F W+
Sbjct: 123 IYVWQGRMSSLQERKAAFSRAVGFIQAKGYPTYTNVEVVNDGAESAAFKQLFRTWS 178
Score = 38.3 bits (85), Expect = 0.066
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
Query: 17 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAA 76
+E+W I++ V + G +G+ Y+VL T R+ + ++ W G + + DE A
Sbjct: 223 VEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQRLGRVQYILYLWQGHQATADEIEAL 282
Query: 77 AILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
L D + G VQ E FL F
Sbjct: 283 NSNAEEL-DVMYGGVLVQEHVTMGSEPPHFLAIF 315
>U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein.
Length = 1269
Score = 82.2 bits (194), Expect = 4e-15
Identities = 44/103 (42%), Positives = 59/103 (57%), Gaps = 4/103 (3%)
Query: 10 DAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNT-TGDKDRLTWDIHFWLGSRT 68
D G+ PGL IW+IENF PV V + G FY D YIVL T D L W+I++W+G
Sbjct: 494 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 553
Query: 69 SQDEAGAAAILTVNLDDEQFQGSAVQH-REVQYYESKEFLEYF 110
+ D+ +AI VNL + G+ + RE ES+EFL+ F
Sbjct: 554 TLDKKACSAIHAVNL--RNYLGAECRTVREEMGDESEEFLQVF 594
Score = 43.2 bits (97), Expect = 0.002
Identities = 49/204 (24%), Positives = 83/204 (40%), Gaps = 15/204 (7%)
Query: 334 SLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVVDSEAHDG 393
SL+ F+LD I+V+ G +A KA A +I + G+A+I ++
Sbjct: 641 SLDPRFVFLLDRGLDIYVWRGAQATLSSTTKARLFAEKINKNERKGKAEITLLVQGQE-- 698
Query: 394 IFDRFFDALGSGNKEAIADA-EEGGDDQEFERVVTKEVSLSEISDKTGSIRITRLPAP-- 450
F++ALG E E+ Q V + E+ + + P
Sbjct: 699 -LPEFWEALGGEPSEIKKHVPEDFWPPQPKLYKVGLGLGYLELPQINYKLSVEHKQRPKV 757
Query: 451 -------LKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKYHDYPA 503
L + L+T Y+LD +S +++W+GR S +A A+ ++ P
Sbjct: 758 ELMPRMRLLQSLLDTRCVYILDC--WSDVFIWLGRKSPRLVRAAALKLGQELCGMLHRPR 815
Query: 504 WVHVSKVPEGAEPIPFKQYFEDWN 527
VS+ EG E FK F++W+
Sbjct: 816 HATVSRSLEGTEAQVFKAKFKNWD 839
Score = 37.5 bits (83), Expect = 0.12
Identities = 17/51 (33%), Positives = 31/51 (60%), Gaps = 1/51 (1%)
Query: 150 IRYLKGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQVSCTRTYIDPTYI 200
I Y++GG ASGF V R++++ GK+N++++ V T +DP ++
Sbjct: 598 ISYIEGGTASGFYTVEDTHYVT-RMYRVYGKKNIKLEPVPLKGTSLDPRFV 647
>U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog
protein.
Length = 1268
Score = 82.2 bits (194), Expect = 4e-15
Identities = 44/103 (42%), Positives = 59/103 (57%), Gaps = 4/103 (3%)
Query: 10 DAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNT-TGDKDRLTWDIHFWLGSRT 68
D G+ PGL IW+IENF PV V + G FY D YIVL T D L W+I++W+G
Sbjct: 493 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 552
Query: 69 SQDEAGAAAILTVNLDDEQFQGSAVQH-REVQYYESKEFLEYF 110
+ D+ +AI VNL + G+ + RE ES+EFL+ F
Sbjct: 553 TLDKKACSAIHAVNL--RNYLGAECRTVREEMGDESEEFLQVF 593
Score = 43.2 bits (97), Expect = 0.002
Identities = 49/204 (24%), Positives = 83/204 (40%), Gaps = 15/204 (7%)
Query: 334 SLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVVDSEAHDG 393
SL+ F+LD I+V+ G +A KA A +I + G+A+I ++
Sbjct: 640 SLDPRFVFLLDRGLDIYVWRGAQATLSSTTKARLFAEKINKNERKGKAEITLLVQGQE-- 697
Query: 394 IFDRFFDALGSGNKEAIADA-EEGGDDQEFERVVTKEVSLSEISDKTGSIRITRLPAP-- 450
F++ALG E E+ Q V + E+ + + P
Sbjct: 698 -LPEFWEALGGEPSEIKKHVPEDFWPPQPKLYKVGLGLGYLELPQINYKLSVEHKQRPKV 756
Query: 451 -------LKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKYHDYPA 503
L + L+T Y+LD +S +++W+GR S +A A+ ++ P
Sbjct: 757 ELMPRMRLLQSLLDTRCVYILDC--WSDVFIWLGRKSPRLVRAAALKLGQELCGMLHRPR 814
Query: 504 WVHVSKVPEGAEPIPFKQYFEDWN 527
VS+ EG E FK F++W+
Sbjct: 815 HATVSRSLEGTEAQVFKAKFKNWD 838
Score = 37.5 bits (83), Expect = 0.12
Identities = 17/51 (33%), Positives = 31/51 (60%), Gaps = 1/51 (1%)
Query: 150 IRYLKGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQVSCTRTYIDPTYI 200
I Y++GG ASGF V R++++ GK+N++++ V T +DP ++
Sbjct: 597 ISYIEGGTASGFYTVEDTHYVT-RMYRVYGKKNIKLEPVPLKGTSLDPRFV 646
>BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog
(Drosophila) protein.
Length = 1269
Score = 82.2 bits (194), Expect = 4e-15
Identities = 44/103 (42%), Positives = 59/103 (57%), Gaps = 4/103 (3%)
Query: 10 DAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNT-TGDKDRLTWDIHFWLGSRT 68
D G+ PGL IW+IENF PV V + G FY D YIVL T D L W+I++W+G
Sbjct: 494 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 553
Query: 69 SQDEAGAAAILTVNLDDEQFQGSAVQH-REVQYYESKEFLEYF 110
+ D+ +AI VNL + G+ + RE ES+EFL+ F
Sbjct: 554 TLDKKACSAIHAVNL--RNYLGAECRTVREEMGDESEEFLQVF 594
Score = 43.2 bits (97), Expect = 0.002
Identities = 49/204 (24%), Positives = 83/204 (40%), Gaps = 15/204 (7%)
Query: 334 SLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVVDSEAHDG 393
SL+ F+LD I+V+ G +A KA A +I + G+A+I ++
Sbjct: 641 SLDPRFVFLLDRGLDIYVWRGAQATLSSTTKARLFAEKINKNERKGKAEITLLVQGQE-- 698
Query: 394 IFDRFFDALGSGNKEAIADA-EEGGDDQEFERVVTKEVSLSEISDKTGSIRITRLPAP-- 450
F++ALG E E+ Q V + E+ + + P
Sbjct: 699 -LPEFWEALGGEPSEIKKHVPEDFWPPQPKLYKVGLGLGYLELPQINYKLSVEHKQRPKV 757
Query: 451 -------LKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKYHDYPA 503
L + L+T Y+LD +S +++W+GR S +A A+ ++ P
Sbjct: 758 ELMPRMRLLQSLLDTRCVYILDC--WSDVFIWLGRKSPRLVRAAALKLGQELCGMLHRPR 815
Query: 504 WVHVSKVPEGAEPIPFKQYFEDWN 527
VS+ EG E FK F++W+
Sbjct: 816 HATVSRSLEGTEAQVFKAKFKNWD 839
Score = 37.5 bits (83), Expect = 0.12
Identities = 17/51 (33%), Positives = 31/51 (60%), Gaps = 1/51 (1%)
Query: 150 IRYLKGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQVSCTRTYIDPTYI 200
I Y++GG ASGF V R++++ GK+N++++ V T +DP ++
Sbjct: 598 ISYIEGGTASGFYTVEDTHYVT-RMYRVYGKKNIKLEPVPLKGTSLDPRFV 647
>AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog
variant protein.
Length = 1101
Score = 82.2 bits (194), Expect = 4e-15
Identities = 44/103 (42%), Positives = 59/103 (57%), Gaps = 4/103 (3%)
Query: 10 DAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNT-TGDKDRLTWDIHFWLGSRT 68
D G+ PGL IW+IENF PV V + G FY D YIVL T D L W+I++W+G
Sbjct: 481 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 540
Query: 69 SQDEAGAAAILTVNLDDEQFQGSAVQH-REVQYYESKEFLEYF 110
+ D+ +AI VNL + G+ + RE ES+EFL+ F
Sbjct: 541 TLDKKACSAIHAVNL--RNYLGAECRTVREEMGDESEEFLQVF 581
Score = 37.5 bits (83), Expect = 0.12
Identities = 17/51 (33%), Positives = 31/51 (60%), Gaps = 1/51 (1%)
Query: 150 IRYLKGGHASGFSHVTINEGTEKRLFQIKGKRNVRVKQVSCTRTYIDPTYI 200
I Y++GG ASGF V R++++ GK+N++++ V T +DP ++
Sbjct: 585 ISYIEGGTASGFYTVEDTHYVT-RMYRVYGKKNIKLEPVPLKGTSLDPRFV 634
>AK027778-1|BAB55361.1| 468|Homo sapiens protein ( Homo sapiens
cDNA FLJ14872 fis, clone PLACE1002655, highly similar to
ADSEVERIN. ).
Length = 468
Score = 78.2 bits (184), Expect = 7e-14
Identities = 35/94 (37%), Positives = 58/94 (61%), Gaps = 2/94 (2%)
Query: 435 ISDKTGSIRITRLPA--PLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRA 492
+SD +GS+R+T + P L ++EC++LD G+ I+VW G+ +N +E+ AM A
Sbjct: 7 VSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTA 66
Query: 493 EQYLKYHDYPAWVHVSKVPEGAEPIPFKQYFEDW 526
E++L+ +Y + +PEG E FKQ+F+DW
Sbjct: 67 EEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDW 100
Score = 60.1 bits (139), Expect = 2e-08
Identities = 40/110 (36%), Positives = 54/110 (49%), Gaps = 7/110 (6%)
Query: 1 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 60
M H D K +EIWR+EN + V + +G FY GD YI+L T + ++ I
Sbjct: 137 MAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI---I 190
Query: 61 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
+ W G+ ++DE +A LTV L D G AVQ R Q E L F
Sbjct: 191 YTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLF 239
Score = 50.4 bits (115), Expect = 2e-05
Identities = 50/212 (23%), Positives = 93/212 (43%), Gaps = 22/212 (10%)
Query: 319 LCSSVFVSKVKPTFESLNNGDCFILDVDHQI-FVFVGEKAKGVERMKAITVANQIKDQDH 377
L S + +V SLN+ D F+L + +++VG+ A E A VA+ +K +
Sbjct: 272 LASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKT- 330
Query: 378 NGRADIEVVDSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISD 437
+ + + E + F+++LG + E + R L S+
Sbjct: 331 -----LRIQEGEEPE----EFWNSLGGKKDYQTSPLLETQAEDHPPR-------LYGCSN 374
Query: 438 KTGSIRITRLPAPLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLK 497
KTG I +P ++ L D+ +LD ++ I++W+G+ +N EK E++ A+ YL+
Sbjct: 375 KTGRFVIEEIPGEFTQDDLAEDDVMLLD--AWEQIFIWIGKDANEVEKKESLKSAKMYLE 432
Query: 498 Y--HDYPAWVHVSKVPEGAEPIPFKQYFEDWN 527
+ + +G EP F +F W+
Sbjct: 433 TDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWD 464
>BC075797-1|AAH75797.1| 85|Homo sapiens Unknown (protein for
MGC:87550) protein.
Length = 85
Score = 72.5 bits (170), Expect = 3e-12
Identities = 30/61 (49%), Positives = 42/61 (68%)
Query: 5 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWL 64
H+ FA AG++ GL++WRIE E V VP++ G FY GD+Y+VL+T T+ +HFWL
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWL 66
Query: 65 G 65
G
Sbjct: 67 G 67
>AL513122-7|CAI14416.1| 485|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 485
Score = 72.1 bits (169), Expect = 4e-12
Identities = 34/114 (29%), Positives = 65/114 (57%), Gaps = 3/114 (2%)
Query: 416 GGDDQEFERVVTKEVS-LSEISDKTGSIRITRLPA--PLKKEQLNTDECYVLDTGSYSGI 472
G +D E ++++ L ++S+ G++ ++ + P + L +++C++LD G I
Sbjct: 14 GTEDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKI 73
Query: 473 YVWVGRGSNLKEKAEAMNRAEQYLKYHDYPAWVHVSKVPEGAEPIPFKQYFEDW 526
+VW G+ +N +E+ A+ A ++ DYP VS +PEG E FKQ+F++W
Sbjct: 74 FVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNW 127
Score = 71.3 bits (167), Expect = 8e-12
Identities = 39/93 (41%), Positives = 51/93 (54%), Gaps = 1/93 (1%)
Query: 18 EIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAAA 77
+IWRIE V V +G FY GDSYI+L R I+ W G++++QDE A+A
Sbjct: 179 QIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASA 238
Query: 78 ILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
ILT L DE+ G+ VQ R VQ E + F
Sbjct: 239 ILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLF 270
Score = 58.0 bits (134), Expect = 8e-08
Identities = 47/167 (28%), Positives = 78/167 (46%), Gaps = 18/167 (10%)
Query: 327 KVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVV 386
+V P +LN+ D F+L +++VG A E+ A + ++ Q ++V
Sbjct: 311 EVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQP------VQVA 364
Query: 387 DSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIRITR 446
+ DG F++ALG K A + D +++ L S+K G I
Sbjct: 365 EGSEPDG----FWEALGG--KAAYRTSPRLKD----KKMDAHPPRLFACSNKIGRFVIEE 414
Query: 447 LPAPLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAE 493
+P L +E L TD+ +LDT + ++VWVG+ S +EK EA+ E
Sbjct: 415 VPGELMQEDLATDDVMLLDT--WDQVFVWVGKDSQEEEKTEALTSGE 459
>X07066-1|CAA30102.1| 69|Homo sapiens protein ( Human gene for
gelsolin exon 4. ).
Length = 69
Score = 71.3 bits (167), Expect = 8e-12
Identities = 28/62 (45%), Positives = 44/62 (70%), Gaps = 1/62 (1%)
Query: 5 HQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKD-RLTWDIHFW 63
H F AG++PGL+IWR+E F+ V VP +G F++GD+Y++L T ++ L +D+H+W
Sbjct: 8 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 67
Query: 64 LG 65
LG
Sbjct: 68 LG 69
>BC004300-1|AAH04300.1| 672|Homo sapiens VILL protein protein.
Length = 672
Score = 70.5 bits (165), Expect = 1e-11
Identities = 49/175 (28%), Positives = 83/175 (47%), Gaps = 18/175 (10%)
Query: 354 GEKAKGVERMKAITVANQIKDQDHNG-RADIEVVDSEAHDGIFDRFFDALGSGNKEAIAD 412
G K E+ + + + ++D++ G RA I VVD EA + +A+ ++
Sbjct: 7 GPKTSISEKARGLALTYSLRDRERGGGRAQIGVVDDEAKAPDLMQIMEAVLGRRVGSLRA 66
Query: 413 AEEGGDDQEFERVVTKEVSLSEISDKTGSIRITRLPAPLKKEQLNTDECYVLDTGSYSGI 472
A D + ++ V L + +K K+ L ++ Y+LD G + I
Sbjct: 67 ATPSKDINQLQKA---NVRLYHVYEKG-------------KDLLQEEDFYILDQGGFK-I 109
Query: 473 YVWVGRGSNLKEKAEAMNRAEQYLKYHDYPAWVHVSKVPEGAEPIPFKQYFEDWN 527
YVW GR S+L+E+ A +RA +++ YP + +V V +GAE FKQ F W+
Sbjct: 110 YVWQGRMSSLQERKAAFSRAVGFIQAKGYPTYTNVEVVNDGAESAAFKQLFRTWS 164
Score = 38.3 bits (85), Expect = 0.066
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
Query: 17 LEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDIHFWLGSRTSQDEAGAA 76
+E+W I++ V + G +G+ Y+VL T R+ + ++ W G + + DE A
Sbjct: 209 VEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQRLGRVQYILYLWQGHQATADEIEAL 268
Query: 77 AILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
L D + G VQ E FL F
Sbjct: 269 NSNAEEL-DVMYGGVLVQEHVTMGSEPPHFLAIF 301
>BC017491-1|AAH17491.1| 285|Homo sapiens Similar to gelsolin
(amyloidosis, Finnish type) protein.
Length = 285
Score = 67.7 bits (158), Expect = 9e-11
Identities = 55/203 (27%), Positives = 96/203 (47%), Gaps = 20/203 (9%)
Query: 327 KVKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVV 386
+V P +LN+ D F+L +++VG A E+ A + ++ Q ++V
Sbjct: 83 EVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQP------VQVA 136
Query: 387 DSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIRITR 446
+ DG F++ALG K A + D +++ L S+K G I
Sbjct: 137 EGSEPDG----FWEALGG--KAAYRTSPRLKD----KKMDAHPPRLFACSNKIGRFVIEE 186
Query: 447 LPAPLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKYH--DYPAW 504
+P L +E L TD+ +LDT + ++VWVG+ S +EK EA+ A++Y++ +
Sbjct: 187 VPGELMQEDLATDDVMLLDT--WDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRR 244
Query: 505 VHVSKVPEGAEPIPFKQYFEDWN 527
++ V +G EP F +F W+
Sbjct: 245 TPITVVKQGFEPPSFVGWFLGWD 267
Score = 34.3 bits (75), Expect = 1.1
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 68 TSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
++QDE A+AILT L DE+ G+ VQ R VQ E + F
Sbjct: 1 STQDEVAASAILTAQL-DEELGGTPVQSRVVQGKEPAHLMSLF 42
>AL513122-9|CAI14417.1| 207|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 207
Score = 67.3 bits (157), Expect = 1e-10
Identities = 55/202 (27%), Positives = 95/202 (47%), Gaps = 20/202 (9%)
Query: 328 VKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVVD 387
V P +LN+ D F+L +++VG A E+ A + ++ Q ++V +
Sbjct: 6 VLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQP------VQVAE 59
Query: 388 SEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIRITRL 447
DG F++ALG K A + D +++ L S+K G I +
Sbjct: 60 GSEPDG----FWEALGG--KAAYRTSPRLKD----KKMDAHPPRLFACSNKIGRFVIEEV 109
Query: 448 PAPLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLKYH--DYPAWV 505
P L +E L TD+ +LDT + ++VWVG+ S +EK EA+ A++Y++ +
Sbjct: 110 PGELMQEDLATDDVMLLDT--WDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRT 167
Query: 506 HVSKVPEGAEPIPFKQYFEDWN 527
++ V +G EP F +F W+
Sbjct: 168 PITVVKQGFEPPSFVGWFLGWD 189
>AK075198-1|BAC11465.1| 396|Homo sapiens protein ( Homo sapiens
cDNA FLJ90717 fis, clone PLACE1008657, highly similar to
Bovine mRNA for adseverin. ).
Length = 396
Score = 60.1 bits (139), Expect = 2e-08
Identities = 40/110 (36%), Positives = 54/110 (49%), Gaps = 7/110 (6%)
Query: 1 MPEVHQAFADAGRKPGLEIWRIENFEPVAVPKTQFGLFYSGDSYIVLNTTGDKDRLTWDI 60
M H D K +EIWR+EN + V + +G FY GD YI+L T + ++ I
Sbjct: 65 MAAQHNMVDDGSGK--VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTY-PRGQI---I 118
Query: 61 HFWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
+ W G+ ++DE +A LTV L D G AVQ R Q E L F
Sbjct: 119 YTWQGANATRDELTTSAFLTVQL-DRSLGGQAVQIRVSQGKEPVHLLSLF 167
Score = 50.4 bits (115), Expect = 2e-05
Identities = 50/212 (23%), Positives = 93/212 (43%), Gaps = 22/212 (10%)
Query: 319 LCSSVFVSKVKPTFESLNNGDCFILDVDHQI-FVFVGEKAKGVERMKAITVANQIKDQDH 377
L S + +V SLN+ D F+L + +++VG+ A E A VA+ +K +
Sbjct: 200 LASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKT- 258
Query: 378 NGRADIEVVDSEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISD 437
+ + + E + F+++LG + E + R L S+
Sbjct: 259 -----LRIQEGEEPE----EFWNSLGGKKDYQTSPLLETQAEDHPPR-------LYGCSN 302
Query: 438 KTGSIRITRLPAPLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAEQYLK 497
KTG I +P ++ L D+ +LD ++ I++W+G+ +N EK E++ A+ YL+
Sbjct: 303 KTGRFVIEEIPGEFTQDDLAEDDVMLLD--AWEQIFIWIGKDANEVEKKESLKSAKMYLE 360
Query: 498 Y--HDYPAWVHVSKVPEGAEPIPFKQYFEDWN 527
+ + +G EP F +F W+
Sbjct: 361 TDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWD 392
>AL160060-2|CAH71301.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 49.6 bits (113), Expect = 3e-05
Identities = 46/170 (27%), Positives = 76/170 (44%), Gaps = 8/170 (4%)
Query: 328 VKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNG-RAD-IEV 385
V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+ + G RA I+
Sbjct: 1033 VEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQTKRELGCRATYIQT 1092
Query: 386 VDS--EAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIR 443
++ H F+ L G + + A + +D+ +E + + + + D
Sbjct: 1093 IEEGINTHTHAAKDFWKLL--GGQTSYQSAGDPKEDELYEAAIIETNCIYRLMDDKLVPD 1150
Query: 444 ITRLPAPLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAE 493
K L E V D G S +YVW G+ L ++ A A+
Sbjct: 1151 DDYWGKIPKCSLLQPKEVLVFDFG--SEVYVWHGKEVTLAQRKIAFQLAK 1198
Score = 41.9 bits (94), Expect = 0.005
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 20/110 (18%)
Query: 17 LEIWRIENFEPVAVPKTQFGLFYSGDSYI------VLNTTGDKDRLTWDIH--------- 61
+++W I F+ +PK G F+ GD+Y+ V G + + +
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
Query: 62 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCF 1433
>AL160060-1|CAH71300.1| 2214|Homo sapiens supervillin protein.
Length = 2214
Score = 49.6 bits (113), Expect = 3e-05
Identities = 46/170 (27%), Positives = 76/170 (44%), Gaps = 8/170 (4%)
Query: 328 VKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNG-RAD-IEV 385
V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+ + G RA I+
Sbjct: 1459 VEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQTKRELGCRATYIQT 1518
Query: 386 VDS--EAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIR 443
++ H F+ L G + + A + +D+ +E + + + + D
Sbjct: 1519 IEEGINTHTHAAKDFWKLL--GGQTSYQSAGDPKEDELYEAAIIETNCIYRLMDDKLVPD 1576
Query: 444 ITRLPAPLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAE 493
K L E V D G S +YVW G+ L ++ A A+
Sbjct: 1577 DDYWGKIPKCSLLQPKEVLVFDFG--SEVYVWHGKEVTLAQRKIAFQLAK 1624
Score = 41.9 bits (94), Expect = 0.005
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 20/110 (18%)
Query: 17 LEIWRIENFEPVAVPKTQFGLFYSGDSYI------VLNTTGDKDRLTWDIH--------- 61
+++W I F+ +PK G F+ GD+Y+ V G + + +
Sbjct: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
Query: 62 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F
Sbjct: 1814 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCF 1859
>AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein.
Length = 2214
Score = 49.6 bits (113), Expect = 3e-05
Identities = 46/170 (27%), Positives = 76/170 (44%), Gaps = 8/170 (4%)
Query: 328 VKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNG-RAD-IEV 385
V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+ + G RA I+
Sbjct: 1459 VEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQTKRELGCRATYIQT 1518
Query: 386 VDS--EAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIR 443
++ H F+ L G + + A + +D+ +E + + + + D
Sbjct: 1519 IEEGINTHTHAAKDFWKLL--GGQTSYQSAGDPKEDELYEAAIIETNCIYRLMDDKLVPD 1576
Query: 444 ITRLPAPLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAE 493
K L E V D G S +YVW G+ L ++ A A+
Sbjct: 1577 DDYWGKIPKCSLLQPKEVLVFDFG--SEVYVWHGKEVTLAQRKIAFQLAK 1624
Score = 41.9 bits (94), Expect = 0.005
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 20/110 (18%)
Query: 17 LEIWRIENFEPVAVPKTQFGLFYSGDSYI------VLNTTGDKDRLTWDIH--------- 61
+++W I F+ +PK G F+ GD+Y+ V G + + +
Sbjct: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
Query: 62 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F
Sbjct: 1814 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCF 1859
>AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 49.6 bits (113), Expect = 3e-05
Identities = 46/170 (27%), Positives = 76/170 (44%), Gaps = 8/170 (4%)
Query: 328 VKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNG-RAD-IEV 385
V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+ + G RA I+
Sbjct: 1033 VEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQTKRELGCRATYIQT 1092
Query: 386 VDS--EAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIR 443
++ H F+ L G + + A + +D+ +E + + + + D
Sbjct: 1093 IEEGINTHTHAAKDFWKLL--GGQTSYQSAGDPKEDELYEAAIIETNCIYRLMDDKLVPD 1150
Query: 444 ITRLPAPLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAE 493
K L E V D G S +YVW G+ L ++ A A+
Sbjct: 1151 DDYWGKIPKCSLLQPKEVLVFDFG--SEVYVWHGKEVTLAQRKIAFQLAK 1198
Score = 41.9 bits (94), Expect = 0.005
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 20/110 (18%)
Query: 17 LEIWRIENFEPVAVPKTQFGLFYSGDSYI------VLNTTGDKDRLTWDIH--------- 61
+++W I F+ +PK G F+ GD+Y+ V G + + +
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
Query: 62 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCF 1433
>AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein.
Length = 2214
Score = 49.6 bits (113), Expect = 3e-05
Identities = 46/170 (27%), Positives = 76/170 (44%), Gaps = 8/170 (4%)
Query: 328 VKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNG-RAD-IEV 385
V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+ + G RA I+
Sbjct: 1459 VEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQTKRELGCRATYIQT 1518
Query: 386 VDS--EAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIR 443
++ H F+ L G + + A + +D+ +E + + + + D
Sbjct: 1519 IEEGINTHTHAAKDFWKLL--GGQTSYQSAGDPKEDELYEAAIIETNCIYRLMDDKLVPD 1576
Query: 444 ITRLPAPLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAE 493
K L E V D G S +YVW G+ L ++ A A+
Sbjct: 1577 DDYWGKIPKCSLLQPKEVLVFDFG--SEVYVWHGKEVTLAQRKIAFQLAK 1624
Score = 41.9 bits (94), Expect = 0.005
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 20/110 (18%)
Query: 17 LEIWRIENFEPVAVPKTQFGLFYSGDSYI------VLNTTGDKDRLTWDIH--------- 61
+++W I F+ +PK G F+ GD+Y+ V G + + +
Sbjct: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813
Query: 62 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F
Sbjct: 1814 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCF 1859
>AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 49.6 bits (113), Expect = 3e-05
Identities = 46/170 (27%), Positives = 76/170 (44%), Gaps = 8/170 (4%)
Query: 328 VKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNG-RAD-IEV 385
V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+ + G RA I+
Sbjct: 1033 VEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQTKRELGCRATYIQT 1092
Query: 386 VDS--EAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIR 443
++ H F+ L G + + A + +D+ +E + + + + D
Sbjct: 1093 IEEGINTHTHAAKDFWKLL--GGQTSYQSAGDPKEDELYEAAIIETNCIYRLMDDKLVPD 1150
Query: 444 ITRLPAPLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAE 493
K L E V D G S +YVW G+ L ++ A A+
Sbjct: 1151 DDYWGKIPKCSLLQPKEVLVFDFG--SEVYVWHGKEVTLAQRKIAFQLAK 1198
Score = 41.9 bits (94), Expect = 0.005
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 20/110 (18%)
Query: 17 LEIWRIENFEPVAVPKTQFGLFYSGDSYI------VLNTTGDKDRLTWDIH--------- 61
+++W I F+ +PK G F+ GD+Y+ V G + + +
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
Query: 62 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCF 1433
>AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 49.6 bits (113), Expect = 3e-05
Identities = 46/170 (27%), Positives = 76/170 (44%), Gaps = 8/170 (4%)
Query: 328 VKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNG-RAD-IEV 385
V+P +LN+GDCF+L H F++VGE A +E+ KA +A I+ + G RA I+
Sbjct: 1033 VEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQTKRELGCRATYIQT 1092
Query: 386 VDS--EAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIR 443
++ H F+ L G + + A + +D+ +E + + + + D
Sbjct: 1093 IEEGINTHTHAAKDFWKLL--GGQTSYQSAGDPKEDELYEAAIIETNCIYRLMDDKLVPD 1150
Query: 444 ITRLPAPLKKEQLNTDECYVLDTGSYSGIYVWVGRGSNLKEKAEAMNRAE 493
K L E V D G S +YVW G+ L ++ A A+
Sbjct: 1151 DDYWGKIPKCSLLQPKEVLVFDFG--SEVYVWHGKEVTLAQRKIAFQLAK 1198
Score = 41.9 bits (94), Expect = 0.005
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 20/110 (18%)
Query: 17 LEIWRIENFEPVAVPKTQFGLFYSGDSYI------VLNTTGDKDRLTWDIH--------- 61
+++W I F+ +PK G F+ GD+Y+ V G + + +
Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387
Query: 62 -FWLGSRTSQDEAGAAAILTVNLDDEQFQGSAVQHREVQYYESKEFLEYF 110
FW G ++ E G +A++TV LD+E +G+ VQ +Q E FL+ F
Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDEE--RGAQVQ--VLQGKEPPCFLQCF 1433
>AL513122-8|CAI14418.1| 188|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 188
Score = 39.1 bits (87), Expect = 0.038
Identities = 37/139 (26%), Positives = 61/139 (43%), Gaps = 16/139 (11%)
Query: 328 VKPTFESLNNGDCFILDVDHQIFVFVGEKAKGVERMKAITVANQIKDQDHNGRADIEVVD 387
V P +LN+ D F+L +++VG A E+ A + ++ Q ++V +
Sbjct: 6 VLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQP------VQVAE 59
Query: 388 SEAHDGIFDRFFDALGSGNKEAIADAEEGGDDQEFERVVTKEVSLSEISDKTGSIRITRL 447
DG F++ALG K A + D +++ L S+K G I +
Sbjct: 60 GSEPDG----FWEALGG--KAAYRTSPRLKD----KKMDAHPPRLFACSNKIGRFVIEEV 109
Query: 448 PAPLKKEQLNTDECYVLDT 466
P L +E L TD+ +LDT
Sbjct: 110 PGELMQEDLATDDVMLLDT 128
>CR457114-1|CAG33395.1| 364|Homo sapiens HAVCR1 protein.
Length = 364
Score = 35.1 bits (77), Expect = 0.62
Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 5/110 (4%)
Query: 208 TTIDTVLC--SSVLIPSSSRAQTDTDPTYIQPRVLYYTTIDTVLCSSVLIPSSSRAQTDT 265
TT+ TV +S +P+++ T PT P + T TVL + + ++S T +
Sbjct: 136 TTVPTVTTVRTSTTVPTTTTVPMTTVPTTTVPTTMSIPTTTTVLTTMTVSTTTSVPTTTS 195
Query: 266 DPTYIQPRVLYYTTIDTVLCSSVLIPSSSRAQTDTDPTYIQPRVLYYTTV 315
PT V TT+ T + + +P + T P+ QP + TT+
Sbjct: 196 IPTTTSVPVT--TTVSTFV-PPMPLPRQNHEPVATSPSSPQPAETHPTTL 242
>BC013325-1|AAH13325.1| 364|Homo sapiens HAVCR1 protein protein.
Length = 364
Score = 35.1 bits (77), Expect = 0.62
Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 5/110 (4%)
Query: 208 TTIDTVLC--SSVLIPSSSRAQTDTDPTYIQPRVLYYTTIDTVLCSSVLIPSSSRAQTDT 265
TT+ TV +S +P+++ T PT P + T TVL + + ++S T +
Sbjct: 136 TTVPTVTTVRTSTTVPTTTTVPMTTVPTTTVPTTMSIPTTTTVLTTMTVSTTTSVPTTTS 195
Query: 266 DPTYIQPRVLYYTTIDTVLCSSVLIPSSSRAQTDTDPTYIQPRVLYYTTV 315
PT V TT+ T + + +P + T P+ QP + TT+
Sbjct: 196 IPTTTSVPVT--TTVSTFV-PPMPLPRQNHEPVATSPSSPQPAETHPTTL 242
>U78550-1|AAC51342.1| 328|Homo sapiens mucin MUC5B protein.
Length = 328
Score = 34.3 bits (75), Expect = 1.1
Identities = 38/113 (33%), Positives = 47/113 (41%), Gaps = 15/113 (13%)
Query: 191 TRTYIDPTYIQPRVLYYTTIDTVLCSSVLIPSSSRAQTDTDPTYIQPRVLYYTTIDTVLC 250
T + I T P VL TT TV S+ PSSS + T P+ I TT T+
Sbjct: 212 TPSSIPGTTHTPTVLT-TTTTTVATGSMATPSSSTQTSGTPPSLI-------TTATTITA 263
Query: 251 S-SVLIPSSSRAQTDTDPTYIQPRVLYYTTIDTVLCSSVLIPSSSRAQTDTDP 302
+ S PSS+ T P VL T SS + PSS+ T T P
Sbjct: 264 TGSTTNPSSTPGTTPIPP------VLTTTATTPAATSSTVTPSSALGTTHTPP 310
Score = 32.7 bits (71), Expect = 3.3
Identities = 33/105 (31%), Positives = 42/105 (40%), Gaps = 14/105 (13%)
Query: 202 PRVLYYTTIDTVLCSSVLI-PSSSRAQTDTDPTYIQPRVLYYTTIDTVLCSSVLIPSSSR 260
P + T + T + + PSSS T P +I TT S + PSS
Sbjct: 164 PGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWIS------TTTTPTTSGSTVTPSSIP 217
Query: 261 AQTDTDPTYIQPRVLYYTTIDTVLCSSVLIPSSSRAQTDTDPTYI 305
T T P VL TT TV S+ PSSS + T P+ I
Sbjct: 218 GTTHT------PTVLT-TTTTTVATGSMATPSSSTQTSGTPPSLI 255
>AK022448-1|BAB14038.1| 126|Homo sapiens protein ( Homo sapiens
cDNA FLJ12386 fis, clone MAMMA1002622, moderately
similar to VILLIN. ).
Length = 126
Score = 33.5 bits (73), Expect = 1.9
Identities = 13/33 (39%), Positives = 20/33 (60%)
Query: 495 YLKYHDYPAWVHVSKVPEGAEPIPFKQYFEDWN 527
++K YP+ +V V +GAE FKQ F+ W+
Sbjct: 66 FIKMKSYPSSTNVETVNDGAESAMFKQLFQKWS 98
>Z72496-1|CAA96577.1| 3570|Homo sapiens mucin MUC5B protein.
Length = 3570
Score = 32.3 bits (70), Expect = 4.3
Identities = 37/113 (32%), Positives = 46/113 (40%), Gaps = 15/113 (13%)
Query: 191 TRTYIDPTYIQPRVLYYTTIDTVLCSSVLIPSSSRAQTDTDPTYIQPRVLYYTTIDTVLC 250
T + I T P VL TT TV S+ PSSS + T P+ TT T+
Sbjct: 766 TPSSIPGTTHTPTVLT-TTTTTVATGSMATPSSSTQTSGTPPSLT-------TTATTITA 817
Query: 251 S-SVLIPSSSRAQTDTDPTYIQPRVLYYTTIDTVLCSSVLIPSSSRAQTDTDP 302
+ S PSS+ T P VL T SS + PSS+ T T P
Sbjct: 818 TGSTTNPSSTPGTTPIPP------VLTTTATTPAATSSTVTPSSALGTTHTPP 864
Score = 32.3 bits (70), Expect = 4.3
Identities = 34/103 (33%), Positives = 42/103 (40%), Gaps = 9/103 (8%)
Query: 202 PRVLYYTTIDTVLCSS-VLIPSSSRAQTDTDPTYIQPRVLYYTTIDTVLCSSVLIPSSSR 260
P + T + T + PSSS T P +I TT T S+V PSS
Sbjct: 3201 PGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVT-PSSIP 3259
Query: 261 AQTDTDPTYIQPRVLYYTTIDTVLCSSVLIPSSSRAQTDTDPT 303
T T RVL TT TV S+ PSSS + T P+
Sbjct: 3260 GTTHT------ARVLT-TTTTTVATGSMATPSSSTQTSGTPPS 3295
>X74955-1|CAA52910.1| 622|Homo sapiens mucin protein.
Length = 622
Score = 32.3 bits (70), Expect = 4.3
Identities = 34/103 (33%), Positives = 42/103 (40%), Gaps = 9/103 (8%)
Query: 202 PRVLYYTTIDTVLCSS-VLIPSSSRAQTDTDPTYIQPRVLYYTTIDTVLCSSVLIPSSSR 260
P + T + T + PSSS T P +I TT T S+V PSS
Sbjct: 416 PGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVT-PSSIP 474
Query: 261 AQTDTDPTYIQPRVLYYTTIDTVLCSSVLIPSSSRAQTDTDPT 303
T T RVL TT TV S+ PSSS + T P+
Sbjct: 475 GTTHT------ARVLT-TTTTTVATGSMATPSSSTQTSGTPPS 510
>AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ
protein protein.
Length = 3222
Score = 31.9 bits (69), Expect = 5.7
Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 5/63 (7%)
Query: 330 PTFESLNNGDCFILDVDHQ--IFV---FVGEKAKGVERMKAITVANQIKDQDHNGRADIE 384
P F S D +LDV+ IF F+ E + + K +TV+ KD NG+ D E
Sbjct: 945 PPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPRKILTVSAMDKDSGPNGQLDYE 1004
Query: 385 VVD 387
+V+
Sbjct: 1005 IVN 1007
>AF007192-1|AAC02270.1| 338|Homo sapiens intestinal mucin protein.
Length = 338
Score = 31.9 bits (69), Expect = 5.7
Identities = 26/108 (24%), Positives = 46/108 (42%), Gaps = 3/108 (2%)
Query: 208 TTIDTVLCSSVLIPSSSRAQTDTDPTYIQPRVLYYTTIDTVLCSSVLIPSSSRAQTDTDP 267
+++ T + SS +PS+ R + T T I P TT+ T + S ++ + T
Sbjct: 187 SSLTTNILSSTPVPSTERTTSHT--TNINPVSTLVTTLPTTITRSTPTSETTYPISSTST 244
Query: 268 -TYIQPRVLYYTTIDTVLCSSVLIPSSSRAQTDTDPTYIQPRVLYYTT 314
T + Y TT+ S+ +P +S + T+ +L TT
Sbjct: 245 VTESTTEITYSTTMTETSSSATSLPLTSPLVSTTETAKTPTTILVTTT 292
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.135 0.402
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 80,278,581
Number of Sequences: 224733
Number of extensions: 3552464
Number of successful extensions: 6320
Number of sequences better than 10.0: 51
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 5878
Number of HSP's gapped (non-prelim): 307
length of query: 527
length of database: 73,234,838
effective HSP length: 93
effective length of query: 434
effective length of database: 52,334,669
effective search space: 22713246346
effective search space used: 22713246346
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 68 (31.5 bits)
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