Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001751-TA|BGIBMGA001751-PA|IPR002048|Calcium-binding
EF-hand
(217 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q8MZH7 Cluster: LD16191p; n=9; Endopterygota|Rep: LD161... 205 6e-52
UniRef50_UPI000058735F Cluster: PREDICTED: similar to Multiple c... 109 7e-23
UniRef50_Q20796 Cluster: Putative uncharacterized protein; n=3; ... 106 4e-22
UniRef50_UPI0000D9D429 Cluster: PREDICTED: similar to multiple c... 102 6e-21
UniRef50_Q8NI22 Cluster: Multiple coagulation factor deficiency ... 102 6e-21
UniRef50_UPI0000D55E25 Cluster: PREDICTED: similar to CG17271-PA... 93 4e-18
UniRef50_UPI0000E4919A Cluster: PREDICTED: hypothetical protein;... 87 3e-16
UniRef50_Q0KI91 Cluster: CG12817-PB, isoform B; n=3; Drosophila ... 69 1e-10
UniRef50_Q4PM41 Cluster: Multiple coagulation factor deficiency ... 67 3e-10
UniRef50_A7SFP6 Cluster: Predicted protein; n=1; Nematostella ve... 65 1e-09
UniRef50_Q7Q641 Cluster: ENSANGP00000012495; n=2; Culicidae|Rep:... 62 8e-09
UniRef50_A7SIS2 Cluster: Predicted protein; n=1; Nematostella ve... 62 1e-08
UniRef50_Q68ET6 Cluster: LOC446290 protein; n=3; Euteleostomi|Re... 45 0.002
UniRef50_Q3HKD3 Cluster: Putative uncharacterized protein; n=1; ... 41 0.020
UniRef50_Q9NJB0 Cluster: CALNUC; n=1; Spodoptera frugiperda|Rep:... 38 0.19
UniRef50_A0BUI0 Cluster: Chromosome undetermined scaffold_129, w... 36 0.76
UniRef50_P80303 Cluster: Nucleobindin-2 precursor; n=41; Euteleo... 36 0.76
UniRef50_O95843 Cluster: Guanylyl cyclase-activating protein 3; ... 36 1.0
UniRef50_A7RZI2 Cluster: Predicted protein; n=1; Nematostella ve... 35 1.8
UniRef50_A0CYM9 Cluster: Chromosome undetermined scaffold_31, wh... 34 2.3
UniRef50_P43080 Cluster: Guanylyl cyclase-activating protein 1; ... 34 2.3
UniRef50_Q99674 Cluster: Cell growth regulator with EF hand doma... 34 2.3
UniRef50_Q0TMX9 Cluster: Lipase/acylhydrolase family protein; n=... 34 3.1
UniRef50_Q5CTY5 Cluster: Calcium/calmodulin dependent protein ki... 34 3.1
UniRef50_A0Q5Z5 Cluster: Peptide methionine sulfoxide reductase;... 33 4.1
UniRef50_Q24JZ6 Cluster: Cell growth regulator with EF-hand doma... 33 4.1
UniRef50_A0DXX1 Cluster: Chromosome undetermined scaffold_69, wh... 33 4.1
UniRef50_UPI0000E492AB Cluster: PREDICTED: similar to Nucb2b pro... 33 5.4
UniRef50_Q22VZ5 Cluster: Putative uncharacterized protein; n=1; ... 33 5.4
UniRef50_A0CPJ3 Cluster: Chromosome undetermined scaffold_23, wh... 33 5.4
UniRef50_A3LW32 Cluster: Predicted protein; n=1; Pichia stipitis... 33 5.4
UniRef50_UPI00006A176C Cluster: Nucleobindin-2 precursor (DNA-bi... 32 9.4
UniRef50_A4FJ37 Cluster: Putative uncharacterized protein; n=1; ... 32 9.4
UniRef50_Q7RKA8 Cluster: Putative uncharacterized protein PY0299... 32 9.4
UniRef50_Q54F44 Cluster: Superoxide-generating NADPH oxidase fla... 32 9.4
UniRef50_Q4XZ04 Cluster: Protein kinase, putative; n=5; Plasmodi... 32 9.4
UniRef50_Q5ABT8 Cluster: Hypothetical WRY family protein 1; n=2;... 32 9.4
UniRef50_Q7UJK0 Cluster: Peptide methionine sulfoxide reductase ... 32 9.4
>UniRef50_Q8MZH7 Cluster: LD16191p; n=9; Endopterygota|Rep: LD16191p
- Drosophila melanogaster (Fruit fly)
Length = 281
Score = 205 bits (501), Expect = 6e-52
Identities = 96/132 (72%), Positives = 110/132 (83%), Gaps = 3/132 (2%)
Query: 87 AGHTHHGDPQ-LLNPANIAQERDHIQEHMDVPIDTSKMSDQELQFHYFKMHDADNNNKLD 145
AG HHG PQ +LN NI QER HIQEHM +PIDTSKMS+ ELQFHYFKMHD+DNNNKLD
Sbjct: 127 AGGHHHGQPQQVLNTGNIQQERAHIQEHMQLPIDTSKMSEAELQFHYFKMHDSDNNNKLD 186
Query: 146 GCELIKSLIHWHEQGHKQENPPSEAP-VGEKIFNEDELVNLIDPILNMDDHNRDGYIDYP 204
GCELIKSLIHWHEQG K E P E P V EK+F+++ELV LIDPIL MDD +RDGYIDYP
Sbjct: 187 GCELIKSLIHWHEQGSK-EQPNGEKPHVEEKVFSDEELVALIDPILQMDDTSRDGYIDYP 245
Query: 205 EFVRAQQKSQKQ 216
EF++AQQK+ ++
Sbjct: 246 EFIKAQQKAAEK 257
>UniRef50_UPI000058735F Cluster: PREDICTED: similar to Multiple
coagulation factor deficiency 2; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Multiple
coagulation factor deficiency 2 - Strongylocentrotus
purpuratus
Length = 137
Score = 109 bits (261), Expect = 7e-23
Identities = 57/128 (44%), Positives = 80/128 (62%), Gaps = 16/128 (12%)
Query: 89 HTHHGDP-QLLNPANIAQERDHIQEHMDVPIDT-----SKMSDQELQFHYFKMHDADNNN 142
H G P L+ + Q+ HI+EH+D ID ++M++++LQ HYFK+HD D+NN
Sbjct: 18 HIKVGPPASLMRDRSHIQDIQHIREHLDGIIDIEGIPENEMTEKQLQLHYFKLHDYDHNN 77
Query: 143 KLDGCELIKSLIHWHEQGHKQENPPSEAPVGEKIFNEDELVNLIDPILNMDDHNRDGYID 202
+LDG EL+ ++ H+H G AP E + ED+L+NLIDPIL DD N+DGYID
Sbjct: 78 RLDGLELLNAMTHYHHDG---------APNAEPL-KEDDLMNLIDPILRDDDKNQDGYID 127
Query: 203 YPEFVRAQ 210
YPE+ Q
Sbjct: 128 YPEYAATQ 135
>UniRef50_Q20796 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 186
Score = 106 bits (255), Expect = 4e-22
Identities = 51/117 (43%), Positives = 76/117 (64%), Gaps = 4/117 (3%)
Query: 104 AQERDHIQEHMDVPID-TSKMSDQELQFHYFKMHDADNNNKLDGCELIKSLIHWHEQGHK 162
A++ HI+EH+D +D T+ M+ ++LQFHYF MHD D N KLDG ELIK++ H+H +
Sbjct: 55 ARDEHHIKEHLDGKVDPTANMTPEQLQFHYFNMHDLDKNGKLDGVELIKAITHFHAENPG 114
Query: 163 QENPPSEAPVGEK---IFNEDELVNLIDPILNMDDHNRDGYIDYPEFVRAQQKSQKQ 216
++ + A + + +E EL +ID IL DD N DG+IDY EF++AQ+ + Q
Sbjct: 115 PQHTQNNANANHQPPPLPSEVELETMIDSILKDDDFNADGFIDYGEFLKAQKLREDQ 171
>UniRef50_UPI0000D9D429 Cluster: PREDICTED: similar to multiple
coagulation factor deficiency 2; n=1; Macaca
mulatta|Rep: PREDICTED: similar to multiple coagulation
factor deficiency 2 - Macaca mulatta
Length = 327
Score = 102 bits (245), Expect = 6e-21
Identities = 50/112 (44%), Positives = 71/112 (63%), Gaps = 11/112 (9%)
Query: 102 NIAQERDHIQEHMDVPIDT--SKMSDQELQFHYFKMHDADNNNKLDGCELIKSLIHWHEQ 159
N +++HI EH++ I+ ++MS QELQ HYFKMHD D NN LDG EL ++ H H++
Sbjct: 225 NTVHDQEHIMEHLEGVINKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKE 284
Query: 160 GHKQENPPSEAPVGEKIFNEDELVNLIDPILNMDDHNRDGYIDYPEFVRAQQ 211
++ P + +EDEL+N+ID +L DD N DGYIDY EF ++ Q
Sbjct: 285 EGSEQAP---------LMSEDELINIIDGVLRDDDKNNDGYIDYAEFAKSLQ 327
>UniRef50_Q8NI22 Cluster: Multiple coagulation factor deficiency
protein 2 precursor; n=30; Euteleostomi|Rep: Multiple
coagulation factor deficiency protein 2 precursor - Homo
sapiens (Human)
Length = 146
Score = 102 bits (245), Expect = 6e-21
Identities = 50/112 (44%), Positives = 71/112 (63%), Gaps = 11/112 (9%)
Query: 102 NIAQERDHIQEHMDVPIDT--SKMSDQELQFHYFKMHDADNNNKLDGCELIKSLIHWHEQ 159
N +++HI EH++ I+ ++MS QELQ HYFKMHD D NN LDG EL ++ H H++
Sbjct: 44 NTVHDQEHIMEHLEGVINKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKE 103
Query: 160 GHKQENPPSEAPVGEKIFNEDELVNLIDPILNMDDHNRDGYIDYPEFVRAQQ 211
++ P + +EDEL+N+ID +L DD N DGYIDY EF ++ Q
Sbjct: 104 EGSEQAP---------LMSEDELINIIDGVLRDDDKNNDGYIDYAEFAKSLQ 146
>UniRef50_UPI0000D55E25 Cluster: PREDICTED: similar to CG17271-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG17271-PA - Tribolium castaneum
Length = 219
Score = 93.5 bits (222), Expect = 4e-18
Identities = 44/122 (36%), Positives = 77/122 (63%), Gaps = 10/122 (8%)
Query: 96 QLLNPANIAQERDHIQEHMDVPI---DTSKMSDQELQFHYFKMHDADNNNKLDGCELIKS 152
+L A + +++H+QEH++ I D SKM+D+EL+F+YF++HD D N+KLDG E++ +
Sbjct: 87 KLTQDAELLHDKEHLQEHLEEIIKEPDLSKMTDEELEFYYFQVHDTDKNSKLDGLEILNA 146
Query: 153 LIHW-HEQGHKQENPPSEAPVGEKIFNEDELVNLIDPILNMDDHNRDGYIDYPEFVRAQQ 211
++H HE+ H+ E + + + V LID +L DD ++DGY+ YPE+ ++
Sbjct: 147 ILHTAHEEKHE------EGEDTHSLEDFEYYVELIDRVLAEDDSDKDGYLSYPEYTSGRR 200
Query: 212 KS 213
+
Sbjct: 201 NA 202
>UniRef50_UPI0000E4919A Cluster: PREDICTED: hypothetical protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 173
Score = 87.0 bits (206), Expect = 3e-16
Identities = 42/116 (36%), Positives = 73/116 (62%), Gaps = 9/116 (7%)
Query: 105 QERDHIQEHMDVPIDTSK--MSDQELQFHYFKMHDADNNNKLDGCELIKSLIHW--HEQG 160
+ ++H++EH++ +DT + M+D+EL+FHYFK+HD DNN KLDG E++ ++ H E
Sbjct: 62 RNKEHVKEHLEGQVDTDEKEMTDEELEFHYFKLHDFDNNTKLDGLEIMAAISHVVPFEPP 121
Query: 161 HKQENPPSEAPVGEKIFNEDELVNLIDPILNMDDHNRDGYIDYPEFVRAQQKSQKQ 216
K + A K F+ +ID ++ DD+N+DGY+ Y E+V ++++ Q +
Sbjct: 122 EKDMSVNQIADARVKYFS-----GIIDQVMLDDDYNKDGYLTYLEYVLSRRRHQDE 172
>UniRef50_Q0KI91 Cluster: CG12817-PB, isoform B; n=3; Drosophila
melanogaster|Rep: CG12817-PB, isoform B - Drosophila
melanogaster (Fruit fly)
Length = 171
Score = 68.5 bits (160), Expect = 1e-10
Identities = 37/103 (35%), Positives = 56/103 (54%), Gaps = 2/103 (1%)
Query: 114 MDVPIDTSKMSDQELQFHYFKMHDADNNNKLDGCELIKSLIHWHEQGHKQENPPSEAPVG 173
M V + +S++E F+ FK HD DNNN LDG E+I+S +H H + + N +A +
Sbjct: 62 MGVQANLDDLSEEEKIFYMFKAHDNDNNNALDGLEMIQSAMH-HNYDYFKNN-ERDAYLQ 119
Query: 174 EKIFNEDELVNLIDPILNMDDHNRDGYIDYPEFVRAQQKSQKQ 216
+ + ID L + D N DG + YPEFV+A ++Q
Sbjct: 120 NATDELEHFIEAIDKFLLIADDNNDGLLHYPEFVKAITGGKEQ 162
>UniRef50_Q4PM41 Cluster: Multiple coagulation factor deficiency
2-like; n=3; Ixodes scapularis|Rep: Multiple coagulation
factor deficiency 2-like - Ixodes scapularis
(Black-legged tick) (Deer tick)
Length = 166
Score = 67.3 bits (157), Expect = 3e-10
Identities = 39/107 (36%), Positives = 59/107 (55%), Gaps = 12/107 (11%)
Query: 102 NIAQERDHIQEHMDVPID---TSKMSDQELQFHYFKMHDADNNNKLDGCELIKSLIHWHE 158
++ ++ +HI++ + I+ MS QEL F+Y +MHD DNNN LDG EL+ ++ H +E
Sbjct: 60 DVVRDLEHIKQDLAKMIELEGAGAMSQQELAFYYLRMHDFDNNNLLDGHELMAAMHHTNE 119
Query: 159 QGHKQENPPSEAPVGEKIFNEDELVNLIDPILNMDDHNRDGYIDYPE 205
H + V DEL+ L D L D N+DG++ YPE
Sbjct: 120 -AHNHDGEGHHTDV-------DELIRLADSALE-GDLNQDGFLSYPE 157
>UniRef50_A7SFP6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 68
Score = 64.9 bits (151), Expect = 1e-09
Identities = 31/77 (40%), Positives = 48/77 (62%), Gaps = 9/77 (11%)
Query: 132 YFKMHDADNNNKLDGCELIKSLIHWHEQGHKQENPPSEAPVGEKIFNEDELVNLIDPILN 191
+F MHD DNN++LDG E++ SL H H + + N K ++++L++ +D ILN
Sbjct: 1 FFLMHDYDNNSRLDGLEILNSLSHNHHEQDAEHN---------KEQSQEQLISFVDLILN 51
Query: 192 MDDHNRDGYIDYPEFVR 208
D ++DGYI Y EF+R
Sbjct: 52 DQDLDKDGYISYAEFIR 68
>UniRef50_Q7Q641 Cluster: ENSANGP00000012495; n=2; Culicidae|Rep:
ENSANGP00000012495 - Anopheles gambiae str. PEST
Length = 107
Score = 62.5 bits (145), Expect = 8e-09
Identities = 29/89 (32%), Positives = 52/89 (58%), Gaps = 6/89 (6%)
Query: 121 SKMSDQELQFHYFKMHDADNNNKLDGCELIKSLIHWHEQGHKQENPPSEAPVGEKIFNED 180
++MS+ E F+YFK+HD+DNN+ LDG E++ + H H + Q + A +D
Sbjct: 7 TEMSEDEKNFYYFKLHDSDNNDNLDGLEMLHAATHHHSKSDGQLHGIDRAATQT---GDD 63
Query: 181 ELVNLIDPILNMDDHNRDGYIDYPEFVRA 209
+ +ID + D +++G ++YPE++ A
Sbjct: 64 Q---VIDDFIEFADTDKNGLLNYPEYINA 89
>UniRef50_A7SIS2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 208
Score = 62.1 bits (144), Expect = 1e-08
Identities = 32/90 (35%), Positives = 50/90 (55%), Gaps = 5/90 (5%)
Query: 118 IDTSKMSDQELQFHYFKMHDADNNNKLDGCELIKSLIHWHEQGHKQENPPSEAPVGEKIF 177
ID K + + F++FK+HD DNN KLDG EL+ +L +HE ++ P E G F
Sbjct: 88 IDIQKGDNNKGIFYFFKLHDYDNNQKLDGLELMSALTDFHE----DDSGPEEKAGGNN-F 142
Query: 178 NEDELVNLIDPILNMDDHNRDGYIDYPEFV 207
+ E ++D +L D N+DG + + E +
Sbjct: 143 LDHEAEAIVDEMLEKHDKNKDGMLQFSELM 172
>UniRef50_Q68ET6 Cluster: LOC446290 protein; n=3; Euteleostomi|Rep:
LOC446290 protein - Xenopus laevis (African clawed frog)
Length = 272
Score = 44.8 bits (101), Expect = 0.002
Identities = 33/120 (27%), Positives = 57/120 (47%), Gaps = 17/120 (14%)
Query: 93 GDPQLLNPANIA-QERDHIQEHMDV--PIDT--SKMSDQELQFHYFKMHDADNNNKLDGC 147
G Q+ NP + +E +QE++ P++T S + + H F +HD D + LDG
Sbjct: 38 GSVQIRNPFSKGPEELSLLQEYLKKKDPLETNASNLKRETAILHLFLLHDYDKSGHLDGL 97
Query: 148 ELIKSLIHWHEQGHKQENPPSEAPVGEKIFNEDELVNLIDPILNMDDHNRDGYIDYPEFV 207
EL++ L H + P+ + +++++D +L D NRDG + PE V
Sbjct: 98 ELMQLLS--GILSHTSQGEPT----------HESVIHMVDEVLERQDLNRDGLLSAPELV 145
>UniRef50_Q3HKD3 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 124
Score = 41.1 bits (92), Expect = 0.020
Identities = 18/58 (31%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Query: 108 DHIQEHMDVPIDTSK-MSDQELQFHYFKMHDADNNNKLDGCELIKSLIHWHEQGHKQE 164
+H+++H I+ K S ++ +F+YFK+ D + +N LDG EL K + ++ K +
Sbjct: 34 EHLKDHYGNKIEIEKHTSSKDRKFYYFKVGDTNQDNHLDGVELFKMITEHSDEKTKMD 91
>UniRef50_Q9NJB0 Cluster: CALNUC; n=1; Spodoptera frugiperda|Rep:
CALNUC - Spodoptera frugiperda (Fall armyworm)
Length = 584
Score = 37.9 bits (84), Expect = 0.19
Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 5/83 (6%)
Query: 132 YFKMHDADNNNKLDGCELIKSLIHWHEQGHKQENPPSEAPVGEKIFNEDELVNLIDPILN 191
+F MHD D N D E +K+L + ++ K P P + +E+ + + +
Sbjct: 238 FFMMHDVDGNGVWDADE-VKAL--FIKELDKLYGPGG--PNKDLHERAEEMERMREHVFK 292
Query: 192 MDDHNRDGYIDYPEFVRAQQKSQ 214
+D NRDG ID+ EF+ QK++
Sbjct: 293 ENDKNRDGLIDFNEFMTETQKAE 315
>UniRef50_A0BUI0 Cluster: Chromosome undetermined scaffold_129,
whole genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_129,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 512
Score = 35.9 bits (79), Expect = 0.76
Identities = 17/41 (41%), Positives = 22/41 (53%)
Query: 175 KIFNEDELVNLIDPILNMDDHNRDGYIDYPEFVRAQQKSQK 215
K+ NE+E V ++ I+ D N G IDY EFV A K
Sbjct: 404 KVMNENEAVEEVERIMRDIDQNNSGTIDYSEFVAASINRSK 444
>UniRef50_P80303 Cluster: Nucleobindin-2 precursor; n=41;
Euteleostomi|Rep: Nucleobindin-2 precursor - Homo
sapiens (Human)
Length = 420
Score = 35.9 bits (79), Expect = 0.76
Identities = 22/83 (26%), Positives = 48/83 (57%), Gaps = 5/83 (6%)
Query: 132 YFKMHDADNNNKLDGCELIKSLIHWHEQGHKQENPPSEAPVGEKIFNEDELVNLIDPILN 191
+FK+HD +++ LD EL ++L + ++ K +P +E + + E+E + + + ++N
Sbjct: 249 FFKLHDVNSDGFLDEQEL-EAL--FTKELEKVYDPKNEED--DMVEMEEERLRMREHVMN 303
Query: 192 MDDHNRDGYIDYPEFVRAQQKSQ 214
D N+D + EF++A +K +
Sbjct: 304 EVDTNKDRLVTLEEFLKATEKKE 326
>UniRef50_O95843 Cluster: Guanylyl cyclase-activating protein 3;
n=18; Tetrapoda|Rep: Guanylyl cyclase-activating protein
3 - Homo sapiens (Human)
Length = 209
Score = 35.5 bits (78), Expect = 1.0
Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 16/90 (17%)
Query: 125 DQELQFHYFKMHDADNNNKLDGCELIKSLIHWHEQGHKQENPPSEAPVGEKIFNEDELVN 184
+Q+L++ YFK++DAD N +D EL+ + +A G++ + +E +N
Sbjct: 90 EQKLKW-YFKLYDADGNGSIDKNELLDMFM------------AVQALNGQQTLSPEEFIN 136
Query: 185 LIDPILNMDDHNRDGYIDYPEFVRAQQKSQ 214
L+ + D N DG + EF+ K Q
Sbjct: 137 LV---FHKIDINNDGELTLEEFINGMAKDQ 163
>UniRef50_A7RZI2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 382
Score = 34.7 bits (76), Expect = 1.8
Identities = 28/121 (23%), Positives = 59/121 (48%), Gaps = 11/121 (9%)
Query: 91 HHGDPQLLNPANIAQERDHIQEHMDVPIDTSKMSDQELQFHYFKMHDADNNNKLDGCELI 150
H+ QL +P + AQ + + E D +D + +FK+HD + + LD EL
Sbjct: 201 HNQSKQLHHPGSKAQ-LEQVWEESD-GLDAKDFDPKT----FFKLHDVNGDGFLDTGELE 254
Query: 151 KSLIHWHEQGHKQENPPSEAPVGEKIFNEDELVNLIDPILNMDDHNRDGYIDYPEFVRAQ 210
+ ++ K NP E ++ ++E+ + + ++N D ++DG++ EF+++
Sbjct: 255 ALFV---KEVTKLYNPKDEDYDPKE--RDEEISRMREHVMNEIDKDKDGFVSQDEFLQSS 309
Query: 211 Q 211
+
Sbjct: 310 K 310
>UniRef50_A0CYM9 Cluster: Chromosome undetermined scaffold_31, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_31,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 783
Score = 34.3 bits (75), Expect = 2.3
Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Query: 119 DTSKMSDQELQFHYFKMHDADNNNKLDGCE--LIKSLIHWHEQGHKQENPPSEAPVGEKI 176
D K S+Q+L ++F A N D + L L Q H++E + V +K+
Sbjct: 641 DLLKHSNQKLDKNHFDQ--ATNTTPYDELKKKLFGQLFEQELQKHQEEKDKFKQEVMKKL 698
Query: 177 FNEDELVNLID 187
FN+D+L NLI+
Sbjct: 699 FNDDDLQNLIE 709
>UniRef50_P43080 Cluster: Guanylyl cyclase-activating protein 1;
n=35; Euteleostomi|Rep: Guanylyl cyclase-activating
protein 1 - Homo sapiens (Human)
Length = 201
Score = 34.3 bits (75), Expect = 2.3
Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 14/90 (15%)
Query: 125 DQELQFHYFKMHDADNNNKLDGCELIKSLIHWHEQGHKQENPPSEAPVGEKIFNEDELVN 184
+Q+L++ YFK++D D N +D EL+ + Q + NP S+ + + F
Sbjct: 89 EQKLRW-YFKLYDVDGNGCIDRDELLTII-----QAIRAINPCSDTTMTAEEFT------ 136
Query: 185 LIDPILNMDDHNRDGYIDYPEFVRAQQKSQ 214
D + + D N DG + EF+ QK Q
Sbjct: 137 --DTVFSKIDVNGDGELSLEEFIEGVQKDQ 164
>UniRef50_Q99674 Cluster: Cell growth regulator with EF hand domain
protein 1; n=12; Eutheria|Rep: Cell growth regulator
with EF hand domain protein 1 - Homo sapiens (Human)
Length = 301
Score = 34.3 bits (75), Expect = 2.3
Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 12/90 (13%)
Query: 118 IDTSKMSDQELQFHYFKMHDADNNNKLDGCELIKSLIHWHEQGHKQENPPSEAPVGEKIF 177
+ +S +++ + F +HD D + +LDG EL+ L G N P+ PV
Sbjct: 63 VQLEHLSREQVLLYLFALHDYDQSGQLDGLELLSMLTAALAPG--AANSPTTNPV----- 115
Query: 178 NEDELVNLIDPILNMDDHNRDGYIDYPEFV 207
+ ++D +L D N DG + E +
Sbjct: 116 -----ILIVDKVLETQDLNGDGLMTPAELI 140
>UniRef50_Q0TMX9 Cluster: Lipase/acylhydrolase family protein; n=3;
Clostridium perfringens|Rep: Lipase/acylhydrolase family
protein - Clostridium perfringens (strain ATCC 13124 /
NCTC 8237 / Type A)
Length = 469
Score = 33.9 bits (74), Expect = 3.1
Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 3/68 (4%)
Query: 97 LLNPANIAQ---ERDHIQEHMDVPIDTSKMSDQELQFHYFKMHDADNNNKLDGCELIKSL 153
+L +NI + R ++ +MD+ + ++ +D L HY D + N EL+ L
Sbjct: 120 ILQTSNIIKMDLSRKSLKFYMDILREVARGNDVMLIDHYSHWEDLEKENSNIKNELLSDL 179
Query: 154 IHWHEQGH 161
IH +E+GH
Sbjct: 180 IHPNEKGH 187
>UniRef50_Q5CTY5 Cluster: Calcium/calmodulin dependent protein
kinase with a kinas domain and 4 calmodulin-like EF
hands; n=3; Cryptosporidium|Rep: Calcium/calmodulin
dependent protein kinase with a kinas domain and 4
calmodulin-like EF hands - Cryptosporidium parvum Iowa
II
Length = 718
Score = 33.9 bits (74), Expect = 3.1
Identities = 26/102 (25%), Positives = 50/102 (49%), Gaps = 14/102 (13%)
Query: 112 EHMDVPIDTSKMSDQELQFHYFKMHDADNNNKLDGCELIKSLIHWHEQGHKQENPPSEAP 171
E + +D+ + S +++ + FK+ D D N K+ EL+ + EQG A
Sbjct: 629 EFIAATLDSKQYSKEQVCWAAFKVFDQDGNGKITANELLNVFSYNSEQG--------SAG 680
Query: 172 VGEKIFNEDELVNLIDPILNMDDHNRDGYIDYPEFVRAQQKS 213
+ +K + ++ N+I + D + DG ID+ EF+ ++S
Sbjct: 681 INDKALS--DVKNMIKEV----DVDGDGEIDFQEFLEMFRRS 716
>UniRef50_A0Q5Z5 Cluster: Peptide methionine sulfoxide reductase;
n=13; Francisella tularensis|Rep: Peptide methionine
sulfoxide reductase - Francisella tularensis subsp.
novicida (strain U112)
Length = 284
Score = 33.5 bits (73), Expect = 4.1
Identities = 26/111 (23%), Positives = 51/111 (45%), Gaps = 2/111 (1%)
Query: 93 GDPQLLNPANIAQERDHIQEHMDVPIDTSKMSDQELQFHYFKMHDAD--NNNKLDGCELI 150
GD + + Q E + V DTSK+S Q++ ++F++HD + + D E
Sbjct: 159 GDQPYPDYKKVCQGDTGYLEVVRVIFDTSKVSLQQVLKYFFEIHDFEQVDGQGPDIGEQY 218
Query: 151 KSLIHWHEQGHKQENPPSEAPVGEKIFNEDELVNLIDPILNMDDHNRDGYI 201
KS I +++ KQ + + +K + + + P +D++ D Y+
Sbjct: 219 KSAIFYYDDKQKQIAEDLKQILAQKGYKVATEIRAMKPYYVAEDYHLDYYM 269
>UniRef50_Q24JZ6 Cluster: Cell growth regulator with EF-hand domain
1; n=3; Laurasiatheria|Rep: Cell growth regulator with
EF-hand domain 1 - Bos taurus (Bovine)
Length = 262
Score = 33.5 bits (73), Expect = 4.1
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 12/85 (14%)
Query: 123 MSDQELQFHYFKMHDADNNNKLDGCELIKSLIHWHEQGHKQENPPSEAPVGEKIFNEDEL 182
MS +++ + F +HD D + +LDG EL+ L G + P+ PV
Sbjct: 68 MSREQVLLYLFALHDYDQSGQLDGLELLSMLTAALAPG--ASDSPTTNPV---------- 115
Query: 183 VNLIDPILNMDDHNRDGYIDYPEFV 207
+ ++D +L D N DG + E V
Sbjct: 116 ILVVDKVLETQDLNGDGLMTPAELV 140
>UniRef50_A0DXX1 Cluster: Chromosome undetermined scaffold_69, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_69, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 3066
Score = 33.5 bits (73), Expect = 4.1
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 10/95 (10%)
Query: 94 DPQLLNPANIAQERDHIQEHMDVPIDTSKMSDQELQFHYFKMHDADNNNKLDGCELIKSL 153
DPQL A +A QE + + DQE+Q K AD NKL+ E++K
Sbjct: 1033 DPQLQESATMASTSKLDQEALQ------RQYDQEVQISRLKDQLADKQNKLEQMEILKEQ 1086
Query: 154 IHWHE---QGHKQENPPSEAPVGEK-IFNEDELVN 184
+ E + +K++ P + ++ + ++ELVN
Sbjct: 1087 LKEKEDELKAYKEQIPSIQEYQNQQFLHQQEELVN 1121
>UniRef50_UPI0000E492AB Cluster: PREDICTED: similar to Nucb2b
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Nucb2b protein -
Strongylocentrotus purpuratus
Length = 383
Score = 33.1 bits (72), Expect = 5.4
Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 6/82 (7%)
Query: 132 YFKMHDADNNNKLDGCELIKSLIHWHEQGHKQENPPSEAPVGEKIFNEDELVNLIDPILN 191
+ +HD++++ LD EL I E+ +K + A V EK +EL + + ++N
Sbjct: 114 FLYLHDSNSDGFLDEFELEALFIKEVEKVYKDQKT---ADVQEKF---EELSRMREHVVN 167
Query: 192 MDDHNRDGYIDYPEFVRAQQKS 213
D+N+D + EF+ A S
Sbjct: 168 QIDNNKDKMVSLAEFMEAASAS 189
>UniRef50_Q22VZ5 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 1340
Score = 33.1 bits (72), Expect = 5.4
Identities = 16/71 (22%), Positives = 35/71 (49%)
Query: 96 QLLNPANIAQERDHIQEHMDVPIDTSKMSDQELQFHYFKMHDADNNNKLDGCELIKSLIH 155
Q+LN + R HI + + P++ + + + Q +YFK ++ N++ + ++ +
Sbjct: 833 QILNSDQFNRNRQHINKFIQQPLNQNMLQVPQKQQYYFKNQNSHNSSAQQNEDSVQISVA 892
Query: 156 WHEQGHKQENP 166
+KQE P
Sbjct: 893 NETDMNKQEYP 903
>UniRef50_A0CPJ3 Cluster: Chromosome undetermined scaffold_23, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_23,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 482
Score = 33.1 bits (72), Expect = 5.4
Identities = 15/42 (35%), Positives = 22/42 (52%)
Query: 174 EKIFNEDELVNLIDPILNMDDHNRDGYIDYPEFVRAQQKSQK 215
+K+ ++ E ++ I+ D N G IDY EFV A QK
Sbjct: 369 KKVISQSEAELQVEQIMKQVDKNESGLIDYSEFVAATINKQK 410
>UniRef50_A3LW32 Cluster: Predicted protein; n=1; Pichia
stipitis|Rep: Predicted protein - Pichia stipitis
(Yeast)
Length = 1142
Score = 33.1 bits (72), Expect = 5.4
Identities = 34/110 (30%), Positives = 50/110 (45%), Gaps = 7/110 (6%)
Query: 96 QLLNPANIAQERDHIQEHM--DVPIDTSKMSDQELQFHYFKMHDADNNNKLDGCELIKSL 153
QLL+ + Q+ D +HM ID +K Q H D D +N L E IK+
Sbjct: 395 QLLDTNMMIQDPDDPTKHMLEKRVIDKTKKVYQRFIIHP-NFIDFDRSNLLS--EEIKNP 451
Query: 154 IHWHEQGHKQEN-PPSEAPVGEKIFNEDELVNLIDPILNMDDHN-RDGYI 201
I W + E+ PSE V N D ++++ D ++ +DH RD I
Sbjct: 452 IQWILDLYNGESIGPSEISVSCLSLNPDIMISISDSLVVSEDHKLRDNQI 501
>UniRef50_UPI00006A176C Cluster: Nucleobindin-2 precursor
(DNA-binding protein NEFA) (Gastric cancer antigen
Zg4).; n=4; Euteleostomi|Rep: Nucleobindin-2 precursor
(DNA-binding protein NEFA) (Gastric cancer antigen Zg4).
- Xenopus tropicalis
Length = 452
Score = 32.3 bits (70), Expect = 9.4
Identities = 22/83 (26%), Positives = 43/83 (51%), Gaps = 6/83 (7%)
Query: 132 YFKMHDADNNNKLDGCELIKSLIHWHEQGHKQENPPSEAPVGEKIFNEDELVNLIDPILN 191
+FK+H + + + E +S++ Q K +P +E + + E+E + + + ++
Sbjct: 253 FFKLHVSWAHGSSECWEFSRSVL----QLEKVYDPNNEED--DMVEMEEERLRMREHVMT 306
Query: 192 MDDHNRDGYIDYPEFVRAQQKSQ 214
D NRD ID EF+RA +K +
Sbjct: 307 EVDLNRDRLIDLQEFIRATEKRE 329
>UniRef50_A4FJ37 Cluster: Putative uncharacterized protein; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep: Putative
uncharacterized protein - Saccharopolyspora erythraea
(strain NRRL 23338)
Length = 99
Score = 32.3 bits (70), Expect = 9.4
Identities = 20/76 (26%), Positives = 37/76 (48%), Gaps = 5/76 (6%)
Query: 132 YFKMHDADNNNKLDGCELIKSLIHWHEQGHKQENPPSEAPVGEKIFNEDELVNLIDPILN 191
+F DAD+N LD E+ L+ +Q P+E G+ +++V + ++
Sbjct: 9 FFASSDADSNGVLDRNEITALLLRHLNDLDRQS--PAEDAAGDAAAKIEQMV---EHLMR 63
Query: 192 MDDHNRDGYIDYPEFV 207
D + DG++ Y EF+
Sbjct: 64 QLDQDGDGHVTYAEFL 79
>UniRef50_Q7RKA8 Cluster: Putative uncharacterized protein PY02993;
n=4; Plasmodium (Vinckeia)|Rep: Putative uncharacterized
protein PY02993 - Plasmodium yoelii yoelii
Length = 1668
Score = 32.3 bits (70), Expect = 9.4
Identities = 19/71 (26%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
Query: 123 MSDQELQFHYFKMHDADNNNKLDGCELIKSLIHWHEQGHKQENPPSEAPVGEKIFNEDEL 182
++ + L+F+ K++ ++ +N + C +K+++ ++ HK E P +E K N+D L
Sbjct: 1179 LNSEYLKFYINKINSSEFSNLVMDCIGLKNMLTCSKEIHKNEIPSNELRNNVKGLNKD-L 1237
Query: 183 VNLIDPILNMD 193
N ID + D
Sbjct: 1238 DNYIDSVEKND 1248
>UniRef50_Q54F44 Cluster: Superoxide-generating NADPH oxidase
flavocytochrome; n=2; Dictyostelium discoideum|Rep:
Superoxide-generating NADPH oxidase flavocytochrome -
Dictyostelium discoideum AX4
Length = 1142
Score = 32.3 bits (70), Expect = 9.4
Identities = 14/30 (46%), Positives = 18/30 (60%)
Query: 177 FNEDELVNLIDPILNMDDHNRDGYIDYPEF 206
F + + +LID I D N DGYID+ EF
Sbjct: 502 FQDFTMESLIDHIFQQFDKNMDGYIDFEEF 531
>UniRef50_Q4XZ04 Cluster: Protein kinase, putative; n=5;
Plasmodium|Rep: Protein kinase, putative - Plasmodium
chabaudi
Length = 192
Score = 32.3 bits (70), Expect = 9.4
Identities = 11/25 (44%), Positives = 19/25 (76%)
Query: 189 ILNMDDHNRDGYIDYPEFVRAQQKS 213
+ N+ D N+DGY+D+ +FV Q+K+
Sbjct: 153 LFNLMDINQDGYLDFEDFVEVQKKN 177
>UniRef50_Q5ABT8 Cluster: Hypothetical WRY family protein 1; n=2;
Candida albicans|Rep: Hypothetical WRY family protein 1
- Candida albicans (Yeast)
Length = 789
Score = 32.3 bits (70), Expect = 9.4
Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Query: 127 ELQFHYFKMHDADNNNKLDGCELIKSLIHWHEQGHKQENPPS--EAPVGEKIFNEDELVN 184
EL H +K + G L+ S + + +QG K + S A V ++ +NE +
Sbjct: 197 ELHKHIYKFAGTSVWLEQHGVHLMLSRVIYSQQGKKNDPQLSLLYAQVYDENWNELNDIE 256
Query: 185 LIDPILNMDDHNRDGYIDYPEFV 207
LI P++N + + YP+FV
Sbjct: 257 LIVPVINPNGERVYDSVKYPQFV 279
>UniRef50_Q7UJK0 Cluster: Peptide methionine sulfoxide reductase
msrA 1 (EC 1.8.4.11) (Protein- methionine-S-oxide
reductase 1) (Peptide-methionine (S)-S-oxide reductase
1) (Peptide Met(O) reductase 1); n=4; Bacteria|Rep:
Peptide methionine sulfoxide reductase msrA 1 (EC
1.8.4.11) (Protein- methionine-S-oxide reductase 1)
(Peptide-methionine (S)-S-oxide reductase 1) (Peptide
Met(O) reductase 1) - Rhodopirellula baltica
Length = 192
Score = 32.3 bits (70), Expect = 9.4
Identities = 25/94 (26%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 112 EHMDVPIDTSKMSDQELQFHYFKMHDADNNNK--LDGCELIKSLIHWHEQGHKQENPPSE 169
E + + D SK + +EL +FK HD N+ DG +S I H ++ +
Sbjct: 68 EAVQIYYDPSKTNFEELLKVFFKTHDPTTLNRQGADGGPQYRSSIFVHNDEQREIAKKTM 127
Query: 170 APVGEKIFNEDELVNLIDPILNM---DDHNRDGY 200
+GE+ D +V LI+P +++++D Y
Sbjct: 128 EKLGEEY--RDPIVTLIEPATKFYVAEEYHQDYY 159
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.136 0.413
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 196,425,309
Number of Sequences: 1657284
Number of extensions: 7650058
Number of successful extensions: 19535
Number of sequences better than 10.0: 38
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 19491
Number of HSP's gapped (non-prelim): 46
length of query: 217
length of database: 575,637,011
effective HSP length: 98
effective length of query: 119
effective length of database: 413,223,179
effective search space: 49173558301
effective search space used: 49173558301
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 70 (32.3 bits)
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