Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001728-TA|BGIBMGA001728-PA|IPR011013|Galactose
mutarotase-like, IPR011682|Glycosyl hydrolases 38, C-terminal
(673 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U68567-1|AAC50812.1| 988|Homo sapiens lysosomal acid alpha-mann... 179 3e-44
U60899-1|AAC51362.1| 1010|Homo sapiens lysosomal alpha-mannosida... 179 3e-44
U60266-1|AAC34130.1| 1011|Homo sapiens lysosomal alpha-mannosida... 179 3e-44
U05572-1|AAB03816.1| 987|Homo sapiens alpha-mannosidase protein. 179 3e-44
BC000736-1|AAH00736.1| 1011|Homo sapiens mannosidase, alpha, cla... 179 3e-44
AB209921-1|BAD93158.1| 1007|Homo sapiens mannosidase, alpha, cla... 179 3e-44
D63998-1|BAA10017.1| 1143|Homo sapiens golgi alpha-mannosidaseII... 47 2e-04
U31520-1|AAC50302.1| 1144|Homo sapiens alpha mannosidase II prot... 46 4e-04
D55649-1|BAA09510.1| 1139|Homo sapiens alpha mannosidase II isoz... 41 0.012
BC094773-1|AAH94773.1| 1009|Homo sapiens mannosidase, alpha, cla... 38 0.15
BC036836-1|AAH36836.1| 358|Homo sapiens MAN2B2 protein protein. 38 0.15
BC033307-1|AAH33307.1| 1009|Homo sapiens mannosidase, alpha, cla... 38 0.15
AL833071-1|CAD89971.1| 1009|Homo sapiens hypothetical protein pr... 38 0.15
AB023152-1|BAA76779.2| 952|Homo sapiens KIAA0935 protein protein. 38 0.15
>U68567-1|AAC50812.1| 988|Homo sapiens lysosomal acid
alpha-mannosidase protein.
Length = 988
Score = 179 bits (435), Expect = 3e-44
Identities = 125/407 (30%), Positives = 203/407 (49%), Gaps = 37/407 (9%)
Query: 210 SKDMFISNKYIRINLDSTRKITNLTLSNNVFLALDVQFYYYASDKPTDTGRTDKKNPGVY 269
S + I N++IR D + ++ N L L V+ ++ + +D+ + G Y
Sbjct: 579 SPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNESDQAS-GAY 637
Query: 270 LFRPVDSNPIPILDFIETIVYKTRVVEEIHCAYSDYVSFVARLYTDLPYIEVDWVVGPVP 329
+FRP P+P+ + + + KT +V+E+H +S + S V RLY ++E++W VGP+P
Sbjct: 638 IFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQRHLELEWSVGPIP 697
Query: 330 VEDGWGKDVFLRYTTDLGNDGAFYTDANGRQTLKRLRNLRATYEPKSSKIXXXXXXXXXX 389
V D WGK+V R+ T L G FYTD+NGR+ L+R R+ R T++ ++
Sbjct: 698 VGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEPVAGN------ 751
Query: 390 XXXVTDKPFQYPCFIFPGNLYPVTSKIYIEDEQKNLRFSIFNDRAQGGTSLTDGELDLMI 449
YP V ++IYI D N++ ++ DR+QGG+SL DG L+LM+
Sbjct: 752 ---------YYP----------VNTRIYITD--GNMQLTVLTDRSQGGSSLRDGSLELMV 790
Query: 450 IRRILTDETGTEMNLNETEYDRGLIVRGKHILYATKMNHKPNMIYEKRLAKEISLEPKVL 509
RR+L D+ G ++ E G VRG+H++ + + LA++ L P+V+
Sbjct: 791 HRRLLKDD-GRGVSEPLMENGSGAWVRGRHLVLLD--TAQAAAAGHRLLAEQEVLAPQVV 847
Query: 510 VSEYGGYGPYLKSKWLGETNEFSALKKKLPLGIHLLSIEQWNEATVLIRLENYL---EKS 566
++ GG L + +FS L++ LP +HLL++ W VL+RLE+ E S
Sbjct: 848 LAPGGGAAYNLGAP---PRTQFSGLRRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDS 904
Query: 567 DAIRSGIKRVYLRDVFVNLRIRSIAECALGGNVWLKDWSPLRWNKKT 613
S + LRD+F I + E L N + S L+W T
Sbjct: 905 GRNLSAPVTLNLRDLFSTFTITRLQETTLVANQLREAASRLKWTTNT 951
>U60899-1|AAC51362.1| 1010|Homo sapiens lysosomal alpha-mannosidase
protein.
Length = 1010
Score = 179 bits (435), Expect = 3e-44
Identities = 125/407 (30%), Positives = 203/407 (49%), Gaps = 37/407 (9%)
Query: 210 SKDMFISNKYIRINLDSTRKITNLTLSNNVFLALDVQFYYYASDKPTDTGRTDKKNPGVY 269
S + I N++IR D + ++ N L L V+ ++ + +D+ + G Y
Sbjct: 601 SPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNESDQAS-GAY 659
Query: 270 LFRPVDSNPIPILDFIETIVYKTRVVEEIHCAYSDYVSFVARLYTDLPYIEVDWVVGPVP 329
+FRP P+P+ + + + KT +V+E+H +S + S V RLY ++E++W VGP+P
Sbjct: 660 IFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQRHLELEWSVGPIP 719
Query: 330 VEDGWGKDVFLRYTTDLGNDGAFYTDANGRQTLKRLRNLRATYEPKSSKIXXXXXXXXXX 389
V D WGK+V R+ T L G FYTD+NGR+ L+R R+ R T++ ++
Sbjct: 720 VGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEPVAGN------ 773
Query: 390 XXXVTDKPFQYPCFIFPGNLYPVTSKIYIEDEQKNLRFSIFNDRAQGGTSLTDGELDLMI 449
YP V ++IYI D N++ ++ DR+QGG+SL DG L+LM+
Sbjct: 774 ---------YYP----------VNTRIYITD--GNMQLTVLTDRSQGGSSLRDGSLELMV 812
Query: 450 IRRILTDETGTEMNLNETEYDRGLIVRGKHILYATKMNHKPNMIYEKRLAKEISLEPKVL 509
RR+L D+ G ++ E G VRG+H++ + + LA++ L P+V+
Sbjct: 813 HRRLLKDD-GRGVSEPLMENGSGAWVRGRHLVLLD--TAQAAAAGHRLLAEQEVLAPQVV 869
Query: 510 VSEYGGYGPYLKSKWLGETNEFSALKKKLPLGIHLLSIEQWNEATVLIRLENYL---EKS 566
++ GG L + +FS L++ LP +HLL++ W VL+RLE+ E S
Sbjct: 870 LAPGGGAAYNLGAP---PRTQFSGLRRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDS 926
Query: 567 DAIRSGIKRVYLRDVFVNLRIRSIAECALGGNVWLKDWSPLRWNKKT 613
S + LRD+F I + E L N + S L+W T
Sbjct: 927 GRNLSAPVTLNLRDLFSTFTITRLQETTLVANQLREAASRLKWTTNT 973
>U60266-1|AAC34130.1| 1011|Homo sapiens lysosomal alpha-mannosidase
protein.
Length = 1011
Score = 179 bits (435), Expect = 3e-44
Identities = 125/407 (30%), Positives = 203/407 (49%), Gaps = 37/407 (9%)
Query: 210 SKDMFISNKYIRINLDSTRKITNLTLSNNVFLALDVQFYYYASDKPTDTGRTDKKNPGVY 269
S + I N++IR D + ++ N L L V+ ++ + +D+ + G Y
Sbjct: 602 SPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNESDQAS-GAY 660
Query: 270 LFRPVDSNPIPILDFIETIVYKTRVVEEIHCAYSDYVSFVARLYTDLPYIEVDWVVGPVP 329
+FRP P+P+ + + + KT +V+E+H +S + S V RLY ++E++W VGP+P
Sbjct: 661 IFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQRHLELEWSVGPIP 720
Query: 330 VEDGWGKDVFLRYTTDLGNDGAFYTDANGRQTLKRLRNLRATYEPKSSKIXXXXXXXXXX 389
V D WGK+V R+ T L G FYTD+NGR+ L+R R+ R T++ ++
Sbjct: 721 VGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEPVAGN------ 774
Query: 390 XXXVTDKPFQYPCFIFPGNLYPVTSKIYIEDEQKNLRFSIFNDRAQGGTSLTDGELDLMI 449
YP V ++IYI D N++ ++ DR+QGG+SL DG L+LM+
Sbjct: 775 ---------YYP----------VNTRIYITD--GNMQLTVLTDRSQGGSSLRDGSLELMV 813
Query: 450 IRRILTDETGTEMNLNETEYDRGLIVRGKHILYATKMNHKPNMIYEKRLAKEISLEPKVL 509
RR+L D+ G ++ E G VRG+H++ + + LA++ L P+V+
Sbjct: 814 HRRLLKDD-GRGVSEPLMENGSGAWVRGRHLVLLD--TAQAAAAGHRLLAEQEVLAPQVV 870
Query: 510 VSEYGGYGPYLKSKWLGETNEFSALKKKLPLGIHLLSIEQWNEATVLIRLENYL---EKS 566
++ GG L + +FS L++ LP +HLL++ W VL+RLE+ E S
Sbjct: 871 LAPGGGAAYNLGAP---PRTQFSGLRRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDS 927
Query: 567 DAIRSGIKRVYLRDVFVNLRIRSIAECALGGNVWLKDWSPLRWNKKT 613
S + LRD+F I + E L N + S L+W T
Sbjct: 928 GRNLSAPVTLNLRDLFSTFTITRLQETTLVANQLREAASRLKWTTNT 974
>U05572-1|AAB03816.1| 987|Homo sapiens alpha-mannosidase protein.
Length = 987
Score = 179 bits (435), Expect = 3e-44
Identities = 125/407 (30%), Positives = 203/407 (49%), Gaps = 37/407 (9%)
Query: 210 SKDMFISNKYIRINLDSTRKITNLTLSNNVFLALDVQFYYYASDKPTDTGRTDKKNPGVY 269
S + I N++IR D + ++ N L L V+ ++ + +D+ + G Y
Sbjct: 578 SPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNESDQAS-GAY 636
Query: 270 LFRPVDSNPIPILDFIETIVYKTRVVEEIHCAYSDYVSFVARLYTDLPYIEVDWVVGPVP 329
+FRP P+P+ + + + KT +V+E+H +S + S V RLY ++E++W VGP+P
Sbjct: 637 IFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQRHLELEWSVGPIP 696
Query: 330 VEDGWGKDVFLRYTTDLGNDGAFYTDANGRQTLKRLRNLRATYEPKSSKIXXXXXXXXXX 389
V D WGK+V R+ T L G FYTD+NGR+ L+R R+ R T++ ++
Sbjct: 697 VGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEPVAGN------ 750
Query: 390 XXXVTDKPFQYPCFIFPGNLYPVTSKIYIEDEQKNLRFSIFNDRAQGGTSLTDGELDLMI 449
YP V ++IYI D N++ ++ DR+QGG+SL DG L+LM+
Sbjct: 751 ---------YYP----------VNTRIYITD--GNMQLTVLTDRSQGGSSLRDGSLELMV 789
Query: 450 IRRILTDETGTEMNLNETEYDRGLIVRGKHILYATKMNHKPNMIYEKRLAKEISLEPKVL 509
RR+L D+ G ++ E G VRG+H++ + + LA++ L P+V+
Sbjct: 790 HRRLLKDD-GRGVSEPLMENGSGAWVRGRHLVLLD--TAQAAAAGHRLLAEQEVLAPQVV 846
Query: 510 VSEYGGYGPYLKSKWLGETNEFSALKKKLPLGIHLLSIEQWNEATVLIRLENYL---EKS 566
++ GG L + +FS L++ LP +HLL++ W VL+RLE+ E S
Sbjct: 847 LAPGGGAAYNLGAP---PRTQFSGLRRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDS 903
Query: 567 DAIRSGIKRVYLRDVFVNLRIRSIAECALGGNVWLKDWSPLRWNKKT 613
S + LRD+F I + E L N + S L+W T
Sbjct: 904 GRNLSAPVTLNLRDLFSTFTITRLQETTLVANQLREAASRLKWTTNT 950
>BC000736-1|AAH00736.1| 1011|Homo sapiens mannosidase, alpha, class
2B, member 1 protein.
Length = 1011
Score = 179 bits (435), Expect = 3e-44
Identities = 125/407 (30%), Positives = 203/407 (49%), Gaps = 37/407 (9%)
Query: 210 SKDMFISNKYIRINLDSTRKITNLTLSNNVFLALDVQFYYYASDKPTDTGRTDKKNPGVY 269
S + I N++IR D + ++ N L L V+ ++ + +D+ + G Y
Sbjct: 602 SPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNESDQAS-GAY 660
Query: 270 LFRPVDSNPIPILDFIETIVYKTRVVEEIHCAYSDYVSFVARLYTDLPYIEVDWVVGPVP 329
+FRP P+P+ + + + KT +V+E+H +S + S V RLY ++E++W VGP+P
Sbjct: 661 IFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQRHLELEWSVGPIP 720
Query: 330 VEDGWGKDVFLRYTTDLGNDGAFYTDANGRQTLKRLRNLRATYEPKSSKIXXXXXXXXXX 389
V D WGK+V R+ T L G FYTD+NGR+ L+R R+ R T++ ++
Sbjct: 721 VGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEPVAGN------ 774
Query: 390 XXXVTDKPFQYPCFIFPGNLYPVTSKIYIEDEQKNLRFSIFNDRAQGGTSLTDGELDLMI 449
YP V ++IYI D N++ ++ DR+QGG+SL DG L+LM+
Sbjct: 775 ---------YYP----------VNTRIYITD--GNMQLTVLTDRSQGGSSLRDGSLELMV 813
Query: 450 IRRILTDETGTEMNLNETEYDRGLIVRGKHILYATKMNHKPNMIYEKRLAKEISLEPKVL 509
RR+L D+ G ++ E G VRG+H++ + + LA++ L P+V+
Sbjct: 814 HRRLLKDD-GRGVSEPLMENGSGAWVRGRHLVLLD--TAQAAAAGHRLLAEQEVLAPQVV 870
Query: 510 VSEYGGYGPYLKSKWLGETNEFSALKKKLPLGIHLLSIEQWNEATVLIRLENYL---EKS 566
++ GG L + +FS L++ LP +HLL++ W VL+RLE+ E S
Sbjct: 871 LAPGGGAAYNLGAP---PRTQFSGLRRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDS 927
Query: 567 DAIRSGIKRVYLRDVFVNLRIRSIAECALGGNVWLKDWSPLRWNKKT 613
S + LRD+F I + E L N + S L+W T
Sbjct: 928 GRNLSAPVTLNLRDLFSTFTITRLQETTLVANQLREAASRLKWTTNT 974
>AB209921-1|BAD93158.1| 1007|Homo sapiens mannosidase, alpha, class
2B, member 1 precursor variant protein.
Length = 1007
Score = 179 bits (435), Expect = 3e-44
Identities = 125/407 (30%), Positives = 203/407 (49%), Gaps = 37/407 (9%)
Query: 210 SKDMFISNKYIRINLDSTRKITNLTLSNNVFLALDVQFYYYASDKPTDTGRTDKKNPGVY 269
S + I N++IR D + ++ N L L V+ ++ + +D+ + G Y
Sbjct: 598 SPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNESDQAS-GAY 656
Query: 270 LFRPVDSNPIPILDFIETIVYKTRVVEEIHCAYSDYVSFVARLYTDLPYIEVDWVVGPVP 329
+FRP P+P+ + + + KT +V+E+H +S + S V RLY ++E++W VGP+P
Sbjct: 657 IFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQRHLELEWSVGPIP 716
Query: 330 VEDGWGKDVFLRYTTDLGNDGAFYTDANGRQTLKRLRNLRATYEPKSSKIXXXXXXXXXX 389
V D WGK+V R+ T L G FYTD+NGR+ L+R R+ R T++ ++
Sbjct: 717 VGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEPVAGN------ 770
Query: 390 XXXVTDKPFQYPCFIFPGNLYPVTSKIYIEDEQKNLRFSIFNDRAQGGTSLTDGELDLMI 449
YP V ++IYI D N++ ++ DR+QGG+SL DG L+LM+
Sbjct: 771 ---------YYP----------VNTRIYITD--GNMQLTVLTDRSQGGSSLRDGSLELMV 809
Query: 450 IRRILTDETGTEMNLNETEYDRGLIVRGKHILYATKMNHKPNMIYEKRLAKEISLEPKVL 509
RR+L D+ G ++ E G VRG+H++ + + LA++ L P+V+
Sbjct: 810 HRRLLKDD-GRGVSEPLMENGSGAWVRGRHLVLLD--TAQAAAAGHRLLAEQEVLAPQVV 866
Query: 510 VSEYGGYGPYLKSKWLGETNEFSALKKKLPLGIHLLSIEQWNEATVLIRLENYL---EKS 566
++ GG L + +FS L++ LP +HLL++ W VL+RLE+ E S
Sbjct: 867 LAPGGGAAYNLGAP---PRTQFSGLRRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDS 923
Query: 567 DAIRSGIKRVYLRDVFVNLRIRSIAECALGGNVWLKDWSPLRWNKKT 613
S + LRD+F I + E L N + S L+W T
Sbjct: 924 GRNLSAPVTLNLRDLFSTFTITRLQETTLVANQLREAASRLKWTTNT 970
>D63998-1|BAA10017.1| 1143|Homo sapiens golgi alpha-mannosidaseII
protein.
Length = 1143
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/144 (25%), Positives = 74/144 (51%), Gaps = 12/144 (8%)
Query: 408 NLYPVTSKIYIEDEQKNLRFSIFNDRAQGGTSLTDGELDLMIIRRILTDET-GTEMNLNE 466
N+YP+T+ YI+D + R ++ + ++ G +SL G++++++ RR++ D+ G E + +
Sbjct: 915 NVYPMTTMAYIQDAKH--RLTLLSAQSLGVSSLNSGQIEVIMDRRLMQDDNRGLEQGIQD 972
Query: 467 TEYDRGL--IVRGKHILYATKMNHKPNMIYEKRLAK-EISLEPKVLVSEYGGYGPYLKSK 523
+ L I+ K T+ K ++ Y L+ SL ++ + P L+ +
Sbjct: 973 NKITANLFRILLEKRSAVNTE-EEKKSVSYPSLLSHITSSLMNHPVIPMANKFSPTLELQ 1031
Query: 524 WLGETNEFSALKKKLPLGIHLLSI 547
EFS L+ LP IHL+++
Sbjct: 1032 -----GEFSPLQSSLPCDIHLVNL 1050
Score = 46.0 bits (104), Expect = 4e-04
Identities = 42/156 (26%), Positives = 73/156 (46%), Gaps = 15/156 (9%)
Query: 215 ISNKYIRINLDSTRKITNL-TLSNNVFLALDVQFYYYASDKPTDTGRTDKKNPGVYLFRP 273
+ N ++ + D T + + T + ++VQF +Y + T + DK G YLF P
Sbjct: 760 LENSFVLLRFDQTGLMKQMMTKEDGKHHEVNVQFSWYGT-----TIKRDKS--GAYLFLP 812
Query: 274 VDSNPIPILDFIETIVYKT--RVVEEIHCAYSDYVSFVARLYTDLPYIEVDWVV--GPVP 329
D N P + V T R+ E+ C + D+V+ RLY + IE V V
Sbjct: 813 -DGNAKPYVYTTPPFVRVTHGRIYSEVTCFF-DHVTHRVRLY-HIQGIEGQSVEVSNIVD 869
Query: 330 VEDGWGKDVFLRYTTDLGNDGAFYTDANGRQTLKRL 365
+ + +++ ++ ++D+ + FYTD NG Q R+
Sbjct: 870 IRKVYNREIAMKISSDIKSQNRFYTDLNGYQIQPRM 905
>U31520-1|AAC50302.1| 1144|Homo sapiens alpha mannosidase II
protein.
Length = 1144
Score = 46.0 bits (104), Expect = 4e-04
Identities = 42/156 (26%), Positives = 73/156 (46%), Gaps = 15/156 (9%)
Query: 215 ISNKYIRINLDSTRKITNL-TLSNNVFLALDVQFYYYASDKPTDTGRTDKKNPGVYLFRP 273
+ N ++ + D T + + T + ++VQF +Y + T + DK G YLF P
Sbjct: 760 LENSFVLLRFDQTGLMKQMMTKEDGKHHEVNVQFSWYGT-----TIKRDKS--GAYLFLP 812
Query: 274 VDSNPIPILDFIETIVYKT--RVVEEIHCAYSDYVSFVARLYTDLPYIEVDWVV--GPVP 329
D N P + V T R+ E+ C + D+V+ RLY + IE V V
Sbjct: 813 -DGNAKPYVYTTPPFVRVTHGRIYSEVTCFF-DHVTHRVRLY-HIQGIEGQSVEVSNIVD 869
Query: 330 VEDGWGKDVFLRYTTDLGNDGAFYTDANGRQTLKRL 365
+ + +++ ++ ++D+ + FYTD NG Q R+
Sbjct: 870 IRKVYNREIAMKISSDIKSQNRFYTDLNGYQIQPRM 905
Score = 44.4 bits (100), Expect = 0.001
Identities = 35/143 (24%), Positives = 70/143 (48%), Gaps = 9/143 (6%)
Query: 408 NLYPVTSKIYIEDEQKNLRFSIFNDRAQGGTSLTDGELDLMIIRRILTDET-GTEMNLNE 466
N+YP+T+ YI+D + R ++ + ++ G +SL G++++++ RR++ D+ G E + +
Sbjct: 915 NVYPMTTMAYIQDAKH--RLTLLSAQSLGVSSLNSGQIEVIMDRRLMQDDNRGLEQGIQD 972
Query: 467 TEYDRGL--IVRGKHILYATKMNHKPNMIYEKRLAKEISLEPKVLVSEYGGYGPYLKSKW 524
+ L I+ K T+ K ++ Y L+ + ++ S
Sbjct: 973 NKITANLFRILLEKRSAVNTE-EEKKSVSYPSLLS---HITSSLMNHPVIPMANKFSSPT 1028
Query: 525 LGETNEFSALKKKLPLGIHLLSI 547
L EFS L+ LP IHL+++
Sbjct: 1029 LELQGEFSPLQSSLPCDIHLVNL 1051
>D55649-1|BAA09510.1| 1139|Homo sapiens alpha mannosidase II isozyme
protein.
Length = 1139
Score = 41.1 bits (92), Expect = 0.012
Identities = 19/50 (38%), Positives = 33/50 (66%), Gaps = 2/50 (4%)
Query: 408 NLYPVTSKIYIEDEQKNLRFSIFNDRAQGGTSLTDGELDLMIIRRILTDE 457
N YP+ YI+D QK R ++ +A G +SL DG+L++++ RR++ D+
Sbjct: 910 NFYPMPVMAYIQDAQK--RLTLHTAQALGVSSLKDGQLEVILDRRLMQDD 957
>BC094773-1|AAH94773.1| 1009|Homo sapiens mannosidase, alpha, class
2B, member 2 protein.
Length = 1009
Score = 37.5 bits (83), Expect = 0.15
Identities = 40/165 (24%), Positives = 71/165 (43%), Gaps = 17/165 (10%)
Query: 408 NLYPVTSKIYIEDEQKNLRFSIFNDRAQGGTSLTDGELDLMIIRRILTDETGTEMNLNET 467
N YP+ ++ED + R + ++RA G +S +G++++M+ RR L + ++ N T
Sbjct: 754 NYYPMVQSAFMEDGKS--RLVLLSERAHGISSQGNGQVEVMLHRR-LWNNFDWDLGYNLT 810
Query: 468 EYDRGLIVRGKHILYATKMNHKPNMIYEKRLAKEISLEPKVLVSEYGGYGPYLKSKWLGE 527
D ++ +L+ + +R A + P VL + G P L +
Sbjct: 811 LNDTSVV---HPVLWLLLGSWSLTTALRQRSALALQHRPVVLFGDLAGTAPKLPGP---Q 864
Query: 528 TNEFSALKKKLPLGIHLLSIEQWNEATVLIRLENYLEKSDAIRSG 572
E L L L +LSI W ++ N+ E S +R G
Sbjct: 865 QQEAVTLPPNLHL--QILSIPGWRYSS------NHTEHSQNLRKG 901
>BC036836-1|AAH36836.1| 358|Homo sapiens MAN2B2 protein protein.
Length = 358
Score = 37.5 bits (83), Expect = 0.15
Identities = 40/165 (24%), Positives = 71/165 (43%), Gaps = 17/165 (10%)
Query: 408 NLYPVTSKIYIEDEQKNLRFSIFNDRAQGGTSLTDGELDLMIIRRILTDETGTEMNLNET 467
N YP+ ++ED + R + ++RA G +S +G++++M+ RR L + ++ N T
Sbjct: 103 NYYPMVQSAFMEDGKS--RLVLLSERAHGISSQGNGQVEVMLHRR-LWNNFDWDLGYNLT 159
Query: 468 EYDRGLIVRGKHILYATKMNHKPNMIYEKRLAKEISLEPKVLVSEYGGYGPYLKSKWLGE 527
D ++ +L+ + +R A + P VL + G P L +
Sbjct: 160 LNDTSVV---HPVLWLLLGSWSLTTALRQRSALALQHRPVVLFGDLAGTAPKLPGP---Q 213
Query: 528 TNEFSALKKKLPLGIHLLSIEQWNEATVLIRLENYLEKSDAIRSG 572
E L L L +LSI W ++ N+ E S +R G
Sbjct: 214 QQEAVTLPPNLHL--QILSIPGWRYSS------NHTEHSQNLRKG 250
>BC033307-1|AAH33307.1| 1009|Homo sapiens mannosidase, alpha, class
2B, member 2 protein.
Length = 1009
Score = 37.5 bits (83), Expect = 0.15
Identities = 40/165 (24%), Positives = 71/165 (43%), Gaps = 17/165 (10%)
Query: 408 NLYPVTSKIYIEDEQKNLRFSIFNDRAQGGTSLTDGELDLMIIRRILTDETGTEMNLNET 467
N YP+ ++ED + R + ++RA G +S +G++++M+ RR L + ++ N T
Sbjct: 754 NYYPMVQSAFMEDGKS--RLVLLSERAHGISSQGNGQVEVMLHRR-LWNNFDWDLGYNLT 810
Query: 468 EYDRGLIVRGKHILYATKMNHKPNMIYEKRLAKEISLEPKVLVSEYGGYGPYLKSKWLGE 527
D ++ +L+ + +R A + P VL + G P L +
Sbjct: 811 LNDTSVV---HPVLWLLLGSWSLTTALRQRSALALQHRPVVLFGDLAGTAPKLPGP---Q 864
Query: 528 TNEFSALKKKLPLGIHLLSIEQWNEATVLIRLENYLEKSDAIRSG 572
E L L L +LSI W ++ N+ E S +R G
Sbjct: 865 QQEAVTLPPNLHL--QILSIPGWRYSS------NHTEHSQNLRKG 901
>AL833071-1|CAD89971.1| 1009|Homo sapiens hypothetical protein
protein.
Length = 1009
Score = 37.5 bits (83), Expect = 0.15
Identities = 40/165 (24%), Positives = 71/165 (43%), Gaps = 17/165 (10%)
Query: 408 NLYPVTSKIYIEDEQKNLRFSIFNDRAQGGTSLTDGELDLMIIRRILTDETGTEMNLNET 467
N YP+ ++ED + R + ++RA G +S +G++++M+ RR L + ++ N T
Sbjct: 754 NYYPMVQSAFMEDGKS--RLVLLSERAHGISSQGNGQVEVMLHRR-LWNNFDWDLGYNLT 810
Query: 468 EYDRGLIVRGKHILYATKMNHKPNMIYEKRLAKEISLEPKVLVSEYGGYGPYLKSKWLGE 527
D ++ +L+ + +R A + P VL + G P L +
Sbjct: 811 LNDTSVV---HPVLWLLLGSWSLTTALRQRSALALQHRPVVLFGDLAGTAPKLPGP---Q 864
Query: 528 TNEFSALKKKLPLGIHLLSIEQWNEATVLIRLENYLEKSDAIRSG 572
E L L L +LSI W ++ N+ E S +R G
Sbjct: 865 QQEAVTLPPNLHL--QILSIPGWRYSS------NHTEHSQNLRKG 901
>AB023152-1|BAA76779.2| 952|Homo sapiens KIAA0935 protein protein.
Length = 952
Score = 37.5 bits (83), Expect = 0.15
Identities = 40/165 (24%), Positives = 71/165 (43%), Gaps = 17/165 (10%)
Query: 408 NLYPVTSKIYIEDEQKNLRFSIFNDRAQGGTSLTDGELDLMIIRRILTDETGTEMNLNET 467
N YP+ ++ED + R + ++RA G +S +G++++M+ RR L + ++ N T
Sbjct: 752 NYYPMVQSAFMEDGKS--RLVLLSERAHGISSQGNGQVEVMLHRR-LWNNFDWDLGYNLT 808
Query: 468 EYDRGLIVRGKHILYATKMNHKPNMIYEKRLAKEISLEPKVLVSEYGGYGPYLKSKWLGE 527
D ++ +L+ + +R A + P VL + G P L +
Sbjct: 809 LNDTSVV---HPVLWLLLGSWSLTTALRQRSALALQHRPVVLFGDLAGTAPKLPGP---Q 862
Query: 528 TNEFSALKKKLPLGIHLLSIEQWNEATVLIRLENYLEKSDAIRSG 572
E L L L +LSI W ++ N+ E S +R G
Sbjct: 863 QQEAVTLPPNLHL--QILSIPGWRYSS------NHTEHSQNLRKG 899
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.136 0.402
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 90,781,519
Number of Sequences: 224733
Number of extensions: 3615754
Number of successful extensions: 9605
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 9563
Number of HSP's gapped (non-prelim): 29
length of query: 673
length of database: 73,234,838
effective HSP length: 95
effective length of query: 578
effective length of database: 51,885,203
effective search space: 29989647334
effective search space used: 29989647334
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 69 (31.9 bits)
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