Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001727-TA|BGIBMGA001727-PA|IPR000602|Glycoside
hydrolase, family 38
(322 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U68567-1|AAC50812.1| 988|Homo sapiens lysosomal acid alpha-mann... 208 2e-53
U60266-1|AAC34130.1| 1011|Homo sapiens lysosomal alpha-mannosida... 208 2e-53
AB209921-1|BAD93158.1| 1007|Homo sapiens mannosidase, alpha, cla... 208 2e-53
U60899-1|AAC51362.1| 1010|Homo sapiens lysosomal alpha-mannosida... 208 3e-53
BC000736-1|AAH00736.1| 1011|Homo sapiens mannosidase, alpha, cla... 208 3e-53
U05572-1|AAB03816.1| 987|Homo sapiens alpha-mannosidase protein. 207 3e-53
U68382-1|AAC50811.1| 323|Homo sapiens truncated lysosomal acid ... 167 3e-41
AL833071-1|CAD89971.1| 1009|Homo sapiens hypothetical protein pr... 90 1e-17
BC094773-1|AAH94773.1| 1009|Homo sapiens mannosidase, alpha, cla... 89 1e-17
BC033307-1|AAH33307.1| 1009|Homo sapiens mannosidase, alpha, cla... 89 1e-17
AB023152-1|BAA76779.2| 952|Homo sapiens KIAA0935 protein protein. 89 1e-17
U31520-1|AAC50302.1| 1144|Homo sapiens alpha mannosidase II prot... 74 6e-13
D63998-1|BAA10017.1| 1143|Homo sapiens golgi alpha-mannosidaseII... 74 6e-13
L28821-1|AAA92022.1| 796|Homo sapiens alpha mannosidase II isoz... 66 2e-10
D55649-1|BAA09510.1| 1139|Homo sapiens alpha mannosidase II isoz... 66 2e-10
>U68567-1|AAC50812.1| 988|Homo sapiens lysosomal acid
alpha-mannosidase protein.
Length = 988
Score = 208 bits (509), Expect = 2e-53
Identities = 123/310 (39%), Positives = 169/310 (54%), Gaps = 25/310 (8%)
Query: 1 MVYTLLRQGRLFIVGGAWGMVDEATTNYHAVIDQFTYSLRKLNATFLECGRPLMAWQADV 60
+V L+RQGRL G W M DEA T+Y A++DQ T LR L TF GRP +AW D
Sbjct: 115 VVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLEDTFGNDGRPRVAWHIDP 174
Query: 61 YGHSREIASLLAQMGFDGLFINPISFDDELDRMRRKSMEFLWRGSDDLGAET-DIYTHKL 119
+GHSRE ASL AQMGFDG F + + D+ RM++ ME +WR S L T D++T L
Sbjct: 175 FGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTADLFTGVL 234
Query: 120 FDGYWSPPGFCFGSYC-DDPLLITSDSVFRNIDERVDLFIKSILHRQAPYYSTRNVMVMM 178
+GY P C+ C D PL+ S N E VD F+ ++ Q YY T ++++ M
Sbjct: 235 PNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFL-NVATAQGRYYRTNHIVMTM 293
Query: 179 GQRFGYYDASIWFANVDKLIKAESPLPHVLPDVPLKWSFLYSEVNKKSYETGANINLYYS 238
G F Y +A++WF N+DKLI+ VN + + G+++++ YS
Sbjct: 294 GSDFQYENANMWFKNLDKLIQL---------------------VNAQQAK-GSSVHVLYS 331
Query: 239 TPACYLKAVYDSNPTLDTKQDDFFPMAYDKFSHATGLYTSRPTIKYMAREGHVYLQMAKQ 298
TPACYL + +N T K DDFFP A TG ++SRP +K R + +LQ+ Q
Sbjct: 332 TPACYLWELNKANLTWSVKHDDFFPYADGHHQFWTGYFSSRPALKRYERLSYNFLQVCNQ 391
Query: 299 LQVLARLWNN 308
L+ L L N
Sbjct: 392 LEALVGLAAN 401
>U60266-1|AAC34130.1| 1011|Homo sapiens lysosomal alpha-mannosidase
protein.
Length = 1011
Score = 208 bits (509), Expect = 2e-53
Identities = 123/310 (39%), Positives = 168/310 (54%), Gaps = 25/310 (8%)
Query: 1 MVYTLLRQGRLFIVGGAWGMVDEATTNYHAVIDQFTYSLRKLNATFLECGRPLMAWQADV 60
+V L+RQGRL G W M DEA T+Y A++DQ T LR L TF GRP +AW D
Sbjct: 138 VVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLEDTFGNVGRPRVAWHIDP 197
Query: 61 YGHSREIASLLAQMGFDGLFINPISFDDELDRMRRKSMEFLWRGSDDLGAET-DIYTHKL 119
+GHSRE ASL AQMGFDG F + + D+ RM++ ME +WR S L T D++T L
Sbjct: 198 FGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTADLFTGVL 257
Query: 120 FDGYWSPPGFCFGSYC-DDPLLITSDSVFRNIDERVDLFIKSILHRQAPYYSTRNVMVMM 178
+GY P C+ C D PL+ S N E VD F+ ++ Q YY T + ++ M
Sbjct: 258 PNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFL-NVATAQGRYYRTNHTVMTM 316
Query: 179 GQRFGYYDASIWFANVDKLIKAESPLPHVLPDVPLKWSFLYSEVNKKSYETGANINLYYS 238
G F Y +A++WF N+DKLI+ VN + + G+++++ YS
Sbjct: 317 GSDFQYENANMWFKNLDKLIRL---------------------VNAQQAK-GSSVHVLYS 354
Query: 239 TPACYLKAVYDSNPTLDTKQDDFFPMAYDKFSHATGLYTSRPTIKYMAREGHVYLQMAKQ 298
TPACYL + +N T K DDFFP A TG ++SRP +K R + +LQ+ Q
Sbjct: 355 TPACYLWELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQ 414
Query: 299 LQVLARLWNN 308
L+ L L N
Sbjct: 415 LEALVGLAAN 424
>AB209921-1|BAD93158.1| 1007|Homo sapiens mannosidase, alpha, class
2B, member 1 precursor variant protein.
Length = 1007
Score = 208 bits (509), Expect = 2e-53
Identities = 123/310 (39%), Positives = 169/310 (54%), Gaps = 25/310 (8%)
Query: 1 MVYTLLRQGRLFIVGGAWGMVDEATTNYHAVIDQFTYSLRKLNATFLECGRPLMAWQADV 60
+V L+RQGRL G W M DEA T+Y A++DQ T LR L TF GRP +AW D
Sbjct: 134 VVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLEDTFGNDGRPRVAWHIDP 193
Query: 61 YGHSREIASLLAQMGFDGLFINPISFDDELDRMRRKSMEFLWRGSDDLGAET-DIYTHKL 119
+GHSRE ASL AQMGFDG F + + D+ RM++ ME +WR S L T D++T L
Sbjct: 194 FGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTADLFTGVL 253
Query: 120 FDGYWSPPGFCFGSYC-DDPLLITSDSVFRNIDERVDLFIKSILHRQAPYYSTRNVMVMM 178
+GY P C+ C D PL+ S N E VD F+ ++ Q YY T ++++ M
Sbjct: 254 PNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFL-NVATAQGRYYRTNHIVMTM 312
Query: 179 GQRFGYYDASIWFANVDKLIKAESPLPHVLPDVPLKWSFLYSEVNKKSYETGANINLYYS 238
G F Y +A++WF N+DKLI+ VN + + G+++++ YS
Sbjct: 313 GSDFQYENANMWFKNLDKLIQL---------------------VNAQQAK-GSSVHVLYS 350
Query: 239 TPACYLKAVYDSNPTLDTKQDDFFPMAYDKFSHATGLYTSRPTIKYMAREGHVYLQMAKQ 298
TPACYL + +N T K DDFFP A TG ++SRP +K R + +LQ+ Q
Sbjct: 351 TPACYLWELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQ 410
Query: 299 LQVLARLWNN 308
L+ L L N
Sbjct: 411 LEALVGLAAN 420
>U60899-1|AAC51362.1| 1010|Homo sapiens lysosomal alpha-mannosidase
protein.
Length = 1010
Score = 208 bits (507), Expect = 3e-53
Identities = 123/310 (39%), Positives = 168/310 (54%), Gaps = 25/310 (8%)
Query: 1 MVYTLLRQGRLFIVGGAWGMVDEATTNYHAVIDQFTYSLRKLNATFLECGRPLMAWQADV 60
+V L+RQGRL G W M DEA T+Y A++DQ T LR L TF GRP +AW D
Sbjct: 137 VVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLEDTFGNDGRPRVAWHIDP 196
Query: 61 YGHSREIASLLAQMGFDGLFINPISFDDELDRMRRKSMEFLWRGSDDLGAET-DIYTHKL 119
+GHSRE ASL AQMGFDG F + + D+ RM++ ME +WR S L T D++T L
Sbjct: 197 FGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTADLFTGVL 256
Query: 120 FDGYWSPPGFCFGSYC-DDPLLITSDSVFRNIDERVDLFIKSILHRQAPYYSTRNVMVMM 178
+GY P C+ C D PL+ S N E VD F+ ++ Q YY T + ++ M
Sbjct: 257 PNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFL-NVATAQGRYYRTNHTVMTM 315
Query: 179 GQRFGYYDASIWFANVDKLIKAESPLPHVLPDVPLKWSFLYSEVNKKSYETGANINLYYS 238
G F Y +A++WF N+DKLI+ VN + + G+++++ YS
Sbjct: 316 GSDFQYENANMWFKNLDKLIRL---------------------VNAQQAK-GSSVHVLYS 353
Query: 239 TPACYLKAVYDSNPTLDTKQDDFFPMAYDKFSHATGLYTSRPTIKYMAREGHVYLQMAKQ 298
TPACYL + +N T K DDFFP A TG ++SRP +K R + +LQ+ Q
Sbjct: 354 TPACYLWELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQ 413
Query: 299 LQVLARLWNN 308
L+ L L N
Sbjct: 414 LEALVGLAAN 423
>BC000736-1|AAH00736.1| 1011|Homo sapiens mannosidase, alpha, class
2B, member 1 protein.
Length = 1011
Score = 208 bits (507), Expect = 3e-53
Identities = 123/310 (39%), Positives = 168/310 (54%), Gaps = 25/310 (8%)
Query: 1 MVYTLLRQGRLFIVGGAWGMVDEATTNYHAVIDQFTYSLRKLNATFLECGRPLMAWQADV 60
+V L+RQGRL G W M DEA T+Y A++DQ T LR L TF GRP +AW D
Sbjct: 138 VVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLEDTFGNDGRPRVAWHIDP 197
Query: 61 YGHSREIASLLAQMGFDGLFINPISFDDELDRMRRKSMEFLWRGSDDLGAET-DIYTHKL 119
+GHSRE ASL AQMGFDG F + + D+ RM++ ME +WR S L T D++T L
Sbjct: 198 FGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTADLFTGVL 257
Query: 120 FDGYWSPPGFCFGSYC-DDPLLITSDSVFRNIDERVDLFIKSILHRQAPYYSTRNVMVMM 178
+GY P C+ C D PL+ S N E VD F+ ++ Q YY T + ++ M
Sbjct: 258 PNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFL-NVATAQGRYYRTNHTVMTM 316
Query: 179 GQRFGYYDASIWFANVDKLIKAESPLPHVLPDVPLKWSFLYSEVNKKSYETGANINLYYS 238
G F Y +A++WF N+DKLI+ VN + + G+++++ YS
Sbjct: 317 GSDFQYENANMWFKNLDKLIRL---------------------VNAQQAK-GSSVHVLYS 354
Query: 239 TPACYLKAVYDSNPTLDTKQDDFFPMAYDKFSHATGLYTSRPTIKYMAREGHVYLQMAKQ 298
TPACYL + +N T K DDFFP A TG ++SRP +K R + +LQ+ Q
Sbjct: 355 TPACYLWELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQ 414
Query: 299 LQVLARLWNN 308
L+ L L N
Sbjct: 415 LEALVGLAAN 424
>U05572-1|AAB03816.1| 987|Homo sapiens alpha-mannosidase protein.
Length = 987
Score = 207 bits (506), Expect = 3e-53
Identities = 123/310 (39%), Positives = 168/310 (54%), Gaps = 26/310 (8%)
Query: 1 MVYTLLRQGRLFIVGGAWGMVDEATTNYHAVIDQFTYSLRKLNATFLECGRPLMAWQADV 60
+V L+RQGRL G W M DEA T+Y A++DQ T LR L TF GRP +AW D
Sbjct: 115 VVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLEDTFGNDGRPRVAWHIDP 174
Query: 61 YGHSREIASLLAQMGFDGLFINPISFDDELDRMRRKSMEFLWRGSDDLGAET-DIYTHKL 119
+GHSRE ASL AQMGFDG F + + D+ RM++ ME +WR S L T D++T L
Sbjct: 175 FGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTADLFTGVL 234
Query: 120 FDGYWSPPGFCFGSYC-DDPLLITSDSVFRNIDERVDLFIKSILHRQAPYYSTRNVMVMM 178
+GY P C+ C D PL+ S N E VD F+ ++ Q YY T + ++ M
Sbjct: 235 PNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFL-NVATAQGRYYRTNHTVMTM 293
Query: 179 GQRFGYYDASIWFANVDKLIKAESPLPHVLPDVPLKWSFLYSEVNKKSYETGANINLYYS 238
G F Y +A++WF N+DKLI+ VN ++ G+++++ YS
Sbjct: 294 GSDFQYENANMWFKNLDKLIRL---------------------VNAQA--KGSSVHVLYS 330
Query: 239 TPACYLKAVYDSNPTLDTKQDDFFPMAYDKFSHATGLYTSRPTIKYMAREGHVYLQMAKQ 298
TPACYL + +N T K DDFFP A TG ++SRP +K R + +LQ+ Q
Sbjct: 331 TPACYLWELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQ 390
Query: 299 LQVLARLWNN 308
L+ L L N
Sbjct: 391 LEALVGLAAN 400
>U68382-1|AAC50811.1| 323|Homo sapiens truncated lysosomal acid
alpha-mannosidase protein.
Length = 323
Score = 167 bits (407), Expect = 3e-41
Identities = 89/201 (44%), Positives = 118/201 (58%), Gaps = 3/201 (1%)
Query: 1 MVYTLLRQGRLFIVGGAWGMVDEATTNYHAVIDQFTYSLRKLNATFLECGRPLMAWQADV 60
+V L+RQGRL G W M DEA T+Y A++DQ T LR L TF GRP +AW D
Sbjct: 115 VVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLEDTFGNDGRPRVAWHIDP 174
Query: 61 YGHSREIASLLAQMGFDGLFINPISFDDELDRMRRKSMEFLWRGSDDLGAET-DIYTHKL 119
+GHSRE ASL AQMGFDG F + + D+ RM++ ME +WR S L T D++T L
Sbjct: 175 FGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTADLFTGVL 234
Query: 120 FDGYWSPPGFCFGSYC-DDPLLITSDSVFRNIDERVDLFIKSILHRQAPYYSTRNVMVMM 178
+GY P C+ C D PL+ S N E VD F+ ++ Q YY T + ++ M
Sbjct: 235 PNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFL-NVATAQGRYYRTNHTVMTM 293
Query: 179 GQRFGYYDASIWFANVDKLIK 199
G F Y +A++WF N+DKLI+
Sbjct: 294 GSDFQYENANMWFKNLDKLIR 314
>AL833071-1|CAD89971.1| 1009|Homo sapiens hypothetical protein
protein.
Length = 1009
Score = 89.8 bits (213), Expect = 1e-17
Identities = 84/315 (26%), Positives = 141/315 (44%), Gaps = 42/315 (13%)
Query: 2 VYTLLRQGRLFIVGGAWGMVDEATTNYHAVIDQFTYSLRKLNATFLECGRPLMAWQADVY 61
V LL +GRL V G M DEA T+ I Q T L TF RP +W D +
Sbjct: 96 VRQLLEEGRLEFVIGGQVMHDEAVTHLDDQILQLTEGHGFLYETFGI--RPQFSWHVDPF 153
Query: 62 GHSREIASLLAQMGFDGLFINPISFDDELDRMRRKSMEFLWRGSDDLGAETDIYTHKLFD 121
G S +L A GF+ + I +D + + ++F+WRGS L +I+TH +
Sbjct: 154 GASATTPTLFALAGFNAHLGSRIDYDLKAAMQEARGLQFVWRGSPSLSERQEIFTHIMDQ 213
Query: 122 -GYWSPPGFCF----GSYCDDPLLI---TSDSVFRNIDE-----RVDLFIKSI---LHRQ 165
Y +P F G Y + + D V+ N+ E ++L+ +++ + ++
Sbjct: 214 YSYCTPSHIPFSNRSGFYWNGVAVFPKPPQDGVYPNMSEPVTPANINLYAEALVANVKQR 273
Query: 166 APYYSTRNVMVMMGQRFGYYDASIWFANVDKLIKAESPLPHVLPDVPLKWSFLYSEVNKK 225
A ++ T +V+ G +++AS+ FAN+D L+ +N
Sbjct: 274 AAWFRTPHVLWPWGCDKQFFNASVQFANMDPLL---------------------DHINSH 312
Query: 226 SYETGANINLYYSTPACYLKAVYDSNPTLDTK-QDDFFPMAYDKFSHATGLYTSRPTIKY 284
+ E G +++ Y+T Y +A++ N T + DF P + + F TG YTSR ++K
Sbjct: 313 AAELG--VSMQYATLGDYFRALHALNVTWRVRDHHDFLPYSTEPFQAWTGFYTSRSSLKG 370
Query: 285 MAREGHVYLQMAKQL 299
+AR L + +
Sbjct: 371 LARRASALLYAGESM 385
>BC094773-1|AAH94773.1| 1009|Homo sapiens mannosidase, alpha, class
2B, member 2 protein.
Length = 1009
Score = 89.4 bits (212), Expect = 1e-17
Identities = 84/315 (26%), Positives = 141/315 (44%), Gaps = 42/315 (13%)
Query: 2 VYTLLRQGRLFIVGGAWGMVDEATTNYHAVIDQFTYSLRKLNATFLECGRPLMAWQADVY 61
V LL +GRL V G M DEA T+ I Q T L TF RP +W D +
Sbjct: 96 VRQLLEEGRLEFVIGGQVMHDEAVTHLDDQILQLTEGHGFLYETFGI--RPQFSWHVDPF 153
Query: 62 GHSREIASLLAQMGFDGLFINPISFDDELDRMRRKSMEFLWRGSDDLGAETDIYTHKLFD 121
G S +L A GF+ + I +D + + ++F+WRGS L +I+TH +
Sbjct: 154 GASATTPTLFALAGFNAHLGSRIDYDLKAAMQEARGLQFVWRGSPSLSERQEIFTHIMDQ 213
Query: 122 -GYWSPPGFCF----GSYCDDPLLITS---DSVFRNIDE-----RVDLFIKSI---LHRQ 165
Y +P F G Y + + D V+ N+ E ++L+ +++ + ++
Sbjct: 214 YSYCTPSHIPFSNRSGFYWNGVAVFPKPPPDGVYPNMSEPVTPANINLYAEALVANVKQR 273
Query: 166 APYYSTRNVMVMMGQRFGYYDASIWFANVDKLIKAESPLPHVLPDVPLKWSFLYSEVNKK 225
A ++ T +V+ G +++AS+ FAN+D L+ +N
Sbjct: 274 AAWFRTPHVLWPWGCDKQFFNASVQFANMDPLL---------------------DHINSH 312
Query: 226 SYETGANINLYYSTPACYLKAVYDSNPTLDTK-QDDFFPMAYDKFSHATGLYTSRPTIKY 284
+ E G +++ Y+T Y +A++ N T + DF P + + F TG YTSR ++K
Sbjct: 313 AAELG--VSVQYATLGDYFRALHALNVTWRVRDHHDFLPYSTEPFQAWTGFYTSRSSLKG 370
Query: 285 MAREGHVYLQMAKQL 299
+AR L + +
Sbjct: 371 LARRASALLYAGESM 385
>BC033307-1|AAH33307.1| 1009|Homo sapiens mannosidase, alpha, class
2B, member 2 protein.
Length = 1009
Score = 89.4 bits (212), Expect = 1e-17
Identities = 84/315 (26%), Positives = 141/315 (44%), Gaps = 42/315 (13%)
Query: 2 VYTLLRQGRLFIVGGAWGMVDEATTNYHAVIDQFTYSLRKLNATFLECGRPLMAWQADVY 61
V LL +GRL V G M DEA T+ I Q T L TF RP +W D +
Sbjct: 96 VRQLLEEGRLEFVIGGQVMHDEAVTHLDDQILQLTEGHGFLYETFGI--RPQFSWHVDPF 153
Query: 62 GHSREIASLLAQMGFDGLFINPISFDDELDRMRRKSMEFLWRGSDDLGAETDIYTHKLFD 121
G S +L A GF+ + I +D + + ++F+WRGS L +I+TH +
Sbjct: 154 GASATTPTLFALAGFNAHLGSRIDYDLKAAMQEARGLQFVWRGSPSLSERQEIFTHIMDQ 213
Query: 122 -GYWSPPGFCF----GSYCDDPLLITS---DSVFRNIDE-----RVDLFIKSI---LHRQ 165
Y +P F G Y + + D V+ N+ E ++L+ +++ + ++
Sbjct: 214 YSYCTPSHIPFSNRSGFYWNGVAVFPKPPPDGVYPNMSEPVTPANINLYAEALVANVKQR 273
Query: 166 APYYSTRNVMVMMGQRFGYYDASIWFANVDKLIKAESPLPHVLPDVPLKWSFLYSEVNKK 225
A ++ T +V+ G +++AS+ FAN+D L+ +N
Sbjct: 274 AAWFRTPHVLWPWGCDKQFFNASVQFANMDPLL---------------------DHINSH 312
Query: 226 SYETGANINLYYSTPACYLKAVYDSNPTLDTK-QDDFFPMAYDKFSHATGLYTSRPTIKY 284
+ E G +++ Y+T Y +A++ N T + DF P + + F TG YTSR ++K
Sbjct: 313 AAELG--VSVQYATLGDYFRALHALNVTWRVRDHHDFLPYSTEPFQAWTGFYTSRSSLKG 370
Query: 285 MAREGHVYLQMAKQL 299
+AR L + +
Sbjct: 371 LARRASALLYAGESM 385
>AB023152-1|BAA76779.2| 952|Homo sapiens KIAA0935 protein protein.
Length = 952
Score = 89.4 bits (212), Expect = 1e-17
Identities = 84/315 (26%), Positives = 141/315 (44%), Gaps = 42/315 (13%)
Query: 2 VYTLLRQGRLFIVGGAWGMVDEATTNYHAVIDQFTYSLRKLNATFLECGRPLMAWQADVY 61
V LL +GRL V G M DEA T+ I Q T L TF RP +W D +
Sbjct: 94 VRQLLEEGRLEFVIGGQVMHDEAVTHLDDQILQLTEGHGFLYETFGI--RPQFSWHVDPF 151
Query: 62 GHSREIASLLAQMGFDGLFINPISFDDELDRMRRKSMEFLWRGSDDLGAETDIYTHKLFD 121
G S +L A GF+ + I +D + + ++F+WRGS L +I+TH +
Sbjct: 152 GASATTPTLFALAGFNAHLGSRIDYDLKAAMQEARGLQFVWRGSPSLSERQEIFTHIMDQ 211
Query: 122 -GYWSPPGFCF----GSYCDDPLLITS---DSVFRNIDE-----RVDLFIKSI---LHRQ 165
Y +P F G Y + + D V+ N+ E ++L+ +++ + ++
Sbjct: 212 YSYCTPSHIPFSNRSGFYWNGVAVFPKPPPDGVYPNMSEPVTPANINLYAEALVANVKQR 271
Query: 166 APYYSTRNVMVMMGQRFGYYDASIWFANVDKLIKAESPLPHVLPDVPLKWSFLYSEVNKK 225
A ++ T +V+ G +++AS+ FAN+D L+ +N
Sbjct: 272 AAWFRTPHVLWPWGCDKQFFNASVQFANMDPLL---------------------DHINSH 310
Query: 226 SYETGANINLYYSTPACYLKAVYDSNPTLDTK-QDDFFPMAYDKFSHATGLYTSRPTIKY 284
+ E G +++ Y+T Y +A++ N T + DF P + + F TG YTSR ++K
Sbjct: 311 AAELG--VSVQYATLGDYFRALHALNVTWRVRDHHDFLPYSTEPFQAWTGFYTSRSSLKG 368
Query: 285 MAREGHVYLQMAKQL 299
+AR L + +
Sbjct: 369 LARRASALLYAGESM 383
>U31520-1|AAC50302.1| 1144|Homo sapiens alpha mannosidase II
protein.
Length = 1144
Score = 74.1 bits (174), Expect = 6e-13
Identities = 42/118 (35%), Positives = 61/118 (51%), Gaps = 2/118 (1%)
Query: 2 VYTLLRQGRLFIVGGAWGMVDEATTNYHAVIDQFTYSLRKLNATFLECGRPLMAWQADVY 61
V +L+ G+L IV G W M DEAT +Y A+IDQ + L +P W D +
Sbjct: 234 VKSLIENGQLEIVTGGWVMPDEATPHYFALIDQLIEGHQWLENNIGV--KPRSGWAIDPF 291
Query: 62 GHSREIASLLAQMGFDGLFINPISFDDELDRMRRKSMEFLWRGSDDLGAETDIYTHKL 119
GHS +A LL + G + I + + + K++EF WR + DLG+ TDI H +
Sbjct: 292 GHSPTMAYLLNRAGLSHMLIQRVHYAVKKHFALHKTLEFFWRQNWDLGSVTDILCHMM 349
>D63998-1|BAA10017.1| 1143|Homo sapiens golgi alpha-mannosidaseII
protein.
Length = 1143
Score = 74.1 bits (174), Expect = 6e-13
Identities = 42/118 (35%), Positives = 61/118 (51%), Gaps = 2/118 (1%)
Query: 2 VYTLLRQGRLFIVGGAWGMVDEATTNYHAVIDQFTYSLRKLNATFLECGRPLMAWQADVY 61
V +L+ G+L IV G W M DEAT +Y A+IDQ + L +P W D +
Sbjct: 234 VKSLIENGQLEIVTGGWVMPDEATPHYFALIDQLIEGHQWLENNIGV--KPRSGWAIDPF 291
Query: 62 GHSREIASLLAQMGFDGLFINPISFDDELDRMRRKSMEFLWRGSDDLGAETDIYTHKL 119
GHS +A LL + G + I + + + K++EF WR + DLG+ TDI H +
Sbjct: 292 GHSPTMAYLLNRAGLSHMLIQRVHYAVKKHFALHKTLEFFWRQNWDLGSVTDILCHMM 349
>L28821-1|AAA92022.1| 796|Homo sapiens alpha mannosidase II isozyme
protein.
Length = 796
Score = 65.7 bits (153), Expect = 2e-10
Identities = 79/321 (24%), Positives = 126/321 (39%), Gaps = 38/321 (11%)
Query: 2 VYTLLRQGRLFIVGGAWGMVDEATTNYHAVIDQFTYSLRKLNATFLECGRPLMAWQADVY 61
V L+ G+L I G W M DEA ++Y A+IDQ + L P W D +
Sbjct: 234 VRRLVGNGQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLERNL--GATPRSGWAVDPF 291
Query: 62 GHSREIASLLAQMGFDGLFINPISFDDELDRMRRKSMEFLWRGSDDLGAETDIYTHKL-F 120
G+S + LL + + I + + + S+EF+WR + D + TDI+ H + F
Sbjct: 292 GYSSTMPYLLRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQTWDSDSSTDIFCHMMPF 351
Query: 121 DGYWSP------PGFCF--------GSYCDDPLLITSDSVFR-NIDERVDLFIKSILHRQ 165
Y P P C G + P + ++ N+ ER L + ++
Sbjct: 352 YSYDVPHTCGPDPKICCQFDFKRLPGGRINCPWKVPPRAITEANVAERAALLLDQ-YRKK 410
Query: 166 APYYSTRNVMVMMGQRFGYYDASIW---FANVDKLIKAESPLPHVLPDVPLKWSFLYSEV 222
+ + + ++V +G F Y W F N +L + P++ V ++ L
Sbjct: 411 SQLFRSNVLLVPLGDDFRYDKPQEWDAQFFNYQRLFDFFNSRPNL--HVQAQFGTLSDYF 468
Query: 223 NKKSYETGANINLYYSTPACYLKAVYDSNPTLDTKQDDFFPMAYDKFSHATGLYTSRPTI 282
+ TG P P DFF A + + TG YTSRP
Sbjct: 469 DALYKRTGVE-------PGA-------RPPGFPVLSGDFFSYADREDHYWTGYYTSRPFY 514
Query: 283 KYMAREGHVYLQMAKQLQVLA 303
K + R +L+ A+ L LA
Sbjct: 515 KSLDRVLEAHLRGAEVLYSLA 535
>D55649-1|BAA09510.1| 1139|Homo sapiens alpha mannosidase II isozyme
protein.
Length = 1139
Score = 65.7 bits (153), Expect = 2e-10
Identities = 79/321 (24%), Positives = 126/321 (39%), Gaps = 38/321 (11%)
Query: 2 VYTLLRQGRLFIVGGAWGMVDEATTNYHAVIDQFTYSLRKLNATFLECGRPLMAWQADVY 61
V L+ G+L I G W M DEA ++Y A+IDQ + L P W D +
Sbjct: 234 VRRLVGNGQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLERNL--GATPRSGWAVDPF 291
Query: 62 GHSREIASLLAQMGFDGLFINPISFDDELDRMRRKSMEFLWRGSDDLGAETDIYTHKL-F 120
G+S + LL + + I + + + S+EF+WR + D + TDI+ H + F
Sbjct: 292 GYSSTMPYLLRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQTWDSDSSTDIFCHMMPF 351
Query: 121 DGYWSP------PGFCF--------GSYCDDPLLITSDSVFR-NIDERVDLFIKSILHRQ 165
Y P P C G + P + ++ N+ ER L + ++
Sbjct: 352 YSYDVPHTCGPDPKICCQFDFKRLPGGRINCPWKVPPRAITEANVAERAALLLDQ-YRKK 410
Query: 166 APYYSTRNVMVMMGQRFGYYDASIW---FANVDKLIKAESPLPHVLPDVPLKWSFLYSEV 222
+ + + ++V +G F Y W F N +L + P++ V ++ L
Sbjct: 411 SQLFRSNVLLVPLGDDFRYDKPQEWDAQFFNYQRLFDFFNSRPNL--HVQAQFGTLSDYF 468
Query: 223 NKKSYETGANINLYYSTPACYLKAVYDSNPTLDTKQDDFFPMAYDKFSHATGLYTSRPTI 282
+ TG P P DFF A + + TG YTSRP
Sbjct: 469 DALYKRTGVE-------PGA-------RPPGFPVLSGDFFSYADREDHYWTGYYTSRPFY 514
Query: 283 KYMAREGHVYLQMAKQLQVLA 303
K + R +L+ A+ L LA
Sbjct: 515 KSLDRVLEAHLRGAEVLYSLA 535
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.324 0.139 0.440
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 50,518,007
Number of Sequences: 224733
Number of extensions: 2096234
Number of successful extensions: 4146
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 4082
Number of HSP's gapped (non-prelim): 33
length of query: 322
length of database: 73,234,838
effective HSP length: 90
effective length of query: 232
effective length of database: 53,008,868
effective search space: 12298057376
effective search space used: 12298057376
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.5 bits)
S2: 65 (30.3 bits)
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