Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001726-TA|BGIBMGA001726-PA|IPR000573|Aconitate
hydratase, C-terminal
(284 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Z11559-1|CAA77651.1| 889|Homo sapiens iron regulatory factor pr... 393 e-109
M58510-1|AAA69900.1| 816|Homo sapiens iron-responsive regulator... 393 e-109
DQ496106-1|ABF47095.1| 889|Homo sapiens aconitase 1, soluble pr... 393 e-109
BC018103-1|AAH18103.1| 889|Homo sapiens aconitase 1, soluble pr... 393 e-109
AL161783-2|CAH72598.1| 889|Homo sapiens aconitase 1, soluble pr... 393 e-109
AF261088-1|AAF99681.1| 790|Homo sapiens iron regulatory protein... 393 e-109
U20180-1|AAA79926.1| 952|Homo sapiens iron-regulatory protein 2... 355 8e-98
M58511-1|AAA69901.1| 963|Homo sapiens iron-responsive element-b... 355 8e-98
DQ496102-1|ABF47091.1| 963|Homo sapiens iron-responsive element... 355 8e-98
BC117483-1|AAI17484.1| 963|Homo sapiens iron-responsive element... 355 8e-98
BC117481-1|AAI17482.1| 963|Homo sapiens iron-responsive element... 355 8e-98
AL133439-1|CAB62825.1| 117|Homo sapiens IRP2; iron-responsive e... 152 1e-36
AB209480-1|BAD92717.1| 781|Homo sapiens aconitase 1 variant pro... 113 5e-25
U87939-1|AAC39921.1| 780|Homo sapiens aconitate hydratase protein. 64 7e-10
U80040-1|AAB38416.1| 780|Homo sapiens mitochondrial aconitase p... 64 7e-10
CR536568-1|CAG38805.1| 780|Homo sapiens ACO2 protein. 64 7e-10
CR456365-1|CAG30251.1| 780|Homo sapiens ACO2 protein. 64 7e-10
BC026196-1|AAH26196.1| 780|Homo sapiens aconitase 2, mitochondr... 64 7e-10
BC014092-1|AAH14092.1| 780|Homo sapiens aconitase 2, mitochondr... 64 7e-10
AL023553-4|CAM28239.1| 805|Homo sapiens aconitase 2, mitochondr... 64 7e-10
AL023553-3|CAI20278.1| 780|Homo sapiens aconitase 2, mitochondr... 64 7e-10
AL008582-4|CAM25244.1| 805|Homo sapiens aconitase 2, mitochondr... 64 7e-10
AL008582-3|CAI17931.1| 780|Homo sapiens aconitase 2, mitochondr... 64 7e-10
AF093096-1|AAD19351.2| 780|Homo sapiens aconitase protein. 64 7e-10
AF086790-1|AAC35557.1| 600|Homo sapiens aconitase precursor pro... 56 1e-07
AB209403-1|BAD92640.1| 802|Homo sapiens iron-responsive element... 46 1e-04
BC112897-1|AAI12898.1| 906|Homo sapiens KIAA0350 protein protein. 31 3.5
>Z11559-1|CAA77651.1| 889|Homo sapiens iron regulatory factor
protein.
Length = 889
Score = 393 bits (968), Expect = e-109
Identities = 181/283 (63%), Positives = 223/283 (78%)
Query: 1 IPVSSVQVYARIEQGSAAWQALDVPRGRLYSWDANSTYIKKPPFFDGMTKELPAATSVRG 60
IP +VY +IE + +W AL P +L+ W++ STYIK PPFF+ +T +L S+
Sbjct: 605 IPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTLDLQPPKSIVD 664
Query: 61 ARCLLLLGDSVTTDHISPAGSIARNSPAARYLAQRGLTAREFNSYGSRRGNDAVMSRGTF 120
A LL LGDSVTTDHISPAG+IARNSPAARYL RGLT REFNSYGSRRGNDAVM+RGTF
Sbjct: 665 AYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAVMARGTF 724
Query: 121 ANIRIVNKMAPAPGPKTTHHPSGDVMDIFDAAERYASEDVPLIAIVGKDYGSGSSRDWAA 180
ANIR++N+ P+T H PSG+++D+FDAAERY +PLI + GK+YG+GSSRDWAA
Sbjct: 725 ANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAGSSRDWAA 784
Query: 181 KGPYLLGIKAVIAESFERIHRSNLVGMGLLPLQFLPGESAATLGLTGAERYDIILPPALA 240
KGP+LLGIKAV+AES+ERIHRSNLVGMG++PL++LPGE+A LGLTG ERY II+P L
Sbjct: 785 KGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTGQERYTIIIPENLK 844
Query: 241 PGQTATVQVDNGTSFQVVVRFDTEVDLTYFKNGGILNYMVRKM 283
P V++D G +FQ V+RFDT+V+LTYF NGGILNYM+RKM
Sbjct: 845 PQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMIRKM 887
>M58510-1|AAA69900.1| 816|Homo sapiens iron-responsive regulatory
protein/iron regulatory protein 1 protein.
Length = 816
Score = 393 bits (968), Expect = e-109
Identities = 181/283 (63%), Positives = 223/283 (78%)
Query: 1 IPVSSVQVYARIEQGSAAWQALDVPRGRLYSWDANSTYIKKPPFFDGMTKELPAATSVRG 60
IP +VY +IE + +W AL P +L+ W++ STYIK PPFF+ +T +L S+
Sbjct: 532 IPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTLDLQPPKSIVD 591
Query: 61 ARCLLLLGDSVTTDHISPAGSIARNSPAARYLAQRGLTAREFNSYGSRRGNDAVMSRGTF 120
A LL LGDSVTTDHISPAG+IARNSPAARYL RGLT REFNSYGSRRGNDAVM+RGTF
Sbjct: 592 AYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAVMARGTF 651
Query: 121 ANIRIVNKMAPAPGPKTTHHPSGDVMDIFDAAERYASEDVPLIAIVGKDYGSGSSRDWAA 180
ANIR++N+ P+T H PSG+++D+FDAAERY +PLI + GK+YG+GSSRDWAA
Sbjct: 652 ANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAGSSRDWAA 711
Query: 181 KGPYLLGIKAVIAESFERIHRSNLVGMGLLPLQFLPGESAATLGLTGAERYDIILPPALA 240
KGP+LLGIKAV+AES+ERIHRSNLVGMG++PL++LPGE+A LGLTG ERY II+P L
Sbjct: 712 KGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTGQERYTIIIPENLK 771
Query: 241 PGQTATVQVDNGTSFQVVVRFDTEVDLTYFKNGGILNYMVRKM 283
P V++D G +FQ V+RFDT+V+LTYF NGGILNYM+RKM
Sbjct: 772 PQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMIRKM 814
>DQ496106-1|ABF47095.1| 889|Homo sapiens aconitase 1, soluble
protein.
Length = 889
Score = 393 bits (968), Expect = e-109
Identities = 181/283 (63%), Positives = 223/283 (78%)
Query: 1 IPVSSVQVYARIEQGSAAWQALDVPRGRLYSWDANSTYIKKPPFFDGMTKELPAATSVRG 60
IP +VY +IE + +W AL P +L+ W++ STYIK PPFF+ +T +L S+
Sbjct: 605 IPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTLDLQPPKSIVD 664
Query: 61 ARCLLLLGDSVTTDHISPAGSIARNSPAARYLAQRGLTAREFNSYGSRRGNDAVMSRGTF 120
A LL LGDSVTTDHISPAG+IARNSPAARYL RGLT REFNSYGSRRGNDAVM+RGTF
Sbjct: 665 AYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAVMARGTF 724
Query: 121 ANIRIVNKMAPAPGPKTTHHPSGDVMDIFDAAERYASEDVPLIAIVGKDYGSGSSRDWAA 180
ANIR++N+ P+T H PSG+++D+FDAAERY +PLI + GK+YG+GSSRDWAA
Sbjct: 725 ANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAGSSRDWAA 784
Query: 181 KGPYLLGIKAVIAESFERIHRSNLVGMGLLPLQFLPGESAATLGLTGAERYDIILPPALA 240
KGP+LLGIKAV+AES+ERIHRSNLVGMG++PL++LPGE+A LGLTG ERY II+P L
Sbjct: 785 KGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTGQERYTIIIPENLK 844
Query: 241 PGQTATVQVDNGTSFQVVVRFDTEVDLTYFKNGGILNYMVRKM 283
P V++D G +FQ V+RFDT+V+LTYF NGGILNYM+RKM
Sbjct: 845 PQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMIRKM 887
>BC018103-1|AAH18103.1| 889|Homo sapiens aconitase 1, soluble
protein.
Length = 889
Score = 393 bits (968), Expect = e-109
Identities = 181/283 (63%), Positives = 223/283 (78%)
Query: 1 IPVSSVQVYARIEQGSAAWQALDVPRGRLYSWDANSTYIKKPPFFDGMTKELPAATSVRG 60
IP +VY +IE + +W AL P +L+ W++ STYIK PPFF+ +T +L S+
Sbjct: 605 IPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTLDLQPPKSIVD 664
Query: 61 ARCLLLLGDSVTTDHISPAGSIARNSPAARYLAQRGLTAREFNSYGSRRGNDAVMSRGTF 120
A LL LGDSVTTDHISPAG+IARNSPAARYL RGLT REFNSYGSRRGNDAVM+RGTF
Sbjct: 665 AYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAVMARGTF 724
Query: 121 ANIRIVNKMAPAPGPKTTHHPSGDVMDIFDAAERYASEDVPLIAIVGKDYGSGSSRDWAA 180
ANIR++N+ P+T H PSG+++D+FDAAERY +PLI + GK+YG+GSSRDWAA
Sbjct: 725 ANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAGSSRDWAA 784
Query: 181 KGPYLLGIKAVIAESFERIHRSNLVGMGLLPLQFLPGESAATLGLTGAERYDIILPPALA 240
KGP+LLGIKAV+AES+ERIHRSNLVGMG++PL++LPGE+A LGLTG ERY II+P L
Sbjct: 785 KGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTGQERYTIIIPENLK 844
Query: 241 PGQTATVQVDNGTSFQVVVRFDTEVDLTYFKNGGILNYMVRKM 283
P V++D G +FQ V+RFDT+V+LTYF NGGILNYM+RKM
Sbjct: 845 PQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMIRKM 887
>AL161783-2|CAH72598.1| 889|Homo sapiens aconitase 1, soluble
protein.
Length = 889
Score = 393 bits (968), Expect = e-109
Identities = 181/283 (63%), Positives = 223/283 (78%)
Query: 1 IPVSSVQVYARIEQGSAAWQALDVPRGRLYSWDANSTYIKKPPFFDGMTKELPAATSVRG 60
IP +VY +IE + +W AL P +L+ W++ STYIK PPFF+ +T +L S+
Sbjct: 605 IPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTLDLQPPKSIVD 664
Query: 61 ARCLLLLGDSVTTDHISPAGSIARNSPAARYLAQRGLTAREFNSYGSRRGNDAVMSRGTF 120
A LL LGDSVTTDHISPAG+IARNSPAARYL RGLT REFNSYGSRRGNDAVM+RGTF
Sbjct: 665 AYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAVMARGTF 724
Query: 121 ANIRIVNKMAPAPGPKTTHHPSGDVMDIFDAAERYASEDVPLIAIVGKDYGSGSSRDWAA 180
ANIR++N+ P+T H PSG+++D+FDAAERY +PLI + GK+YG+GSSRDWAA
Sbjct: 725 ANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAGSSRDWAA 784
Query: 181 KGPYLLGIKAVIAESFERIHRSNLVGMGLLPLQFLPGESAATLGLTGAERYDIILPPALA 240
KGP+LLGIKAV+AES+ERIHRSNLVGMG++PL++LPGE+A LGLTG ERY II+P L
Sbjct: 785 KGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTGQERYTIIIPENLK 844
Query: 241 PGQTATVQVDNGTSFQVVVRFDTEVDLTYFKNGGILNYMVRKM 283
P V++D G +FQ V+RFDT+V+LTYF NGGILNYM+RKM
Sbjct: 845 PQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMIRKM 887
>AF261088-1|AAF99681.1| 790|Homo sapiens iron regulatory protein 1
protein.
Length = 790
Score = 393 bits (968), Expect = e-109
Identities = 181/283 (63%), Positives = 223/283 (78%)
Query: 1 IPVSSVQVYARIEQGSAAWQALDVPRGRLYSWDANSTYIKKPPFFDGMTKELPAATSVRG 60
IP +VY +IE + +W AL P +L+ W++ STYIK PPFF+ +T +L S+
Sbjct: 506 IPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTLDLQPPKSIVD 565
Query: 61 ARCLLLLGDSVTTDHISPAGSIARNSPAARYLAQRGLTAREFNSYGSRRGNDAVMSRGTF 120
A LL LGDSVTTDHISPAG+IARNSPAARYL RGLT REFNSYGSRRGNDAVM+RGTF
Sbjct: 566 AYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAVMARGTF 625
Query: 121 ANIRIVNKMAPAPGPKTTHHPSGDVMDIFDAAERYASEDVPLIAIVGKDYGSGSSRDWAA 180
ANIR++N+ P+T H PSG+++D+FDAAERY +PLI + GK+YG+GSSRDWAA
Sbjct: 626 ANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAGSSRDWAA 685
Query: 181 KGPYLLGIKAVIAESFERIHRSNLVGMGLLPLQFLPGESAATLGLTGAERYDIILPPALA 240
KGP+LLGIKAV+AES+ERIHRSNLVGMG++PL++LPGE+A LGLTG ERY II+P L
Sbjct: 686 KGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTGQERYTIIIPENLK 745
Query: 241 PGQTATVQVDNGTSFQVVVRFDTEVDLTYFKNGGILNYMVRKM 283
P V++D G +FQ V+RFDT+V+LTYF NGGILNYM+RKM
Sbjct: 746 PQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMIRKM 788
>U20180-1|AAA79926.1| 952|Homo sapiens iron-regulatory protein 2
protein.
Length = 952
Score = 355 bits (874), Expect = 8e-98
Identities = 158/272 (58%), Positives = 204/272 (75%)
Query: 11 RIEQGSAAWQALDVPRGRLYSWDANSTYIKKPPFFDGMTKELPAATSVRGARCLLLLGDS 70
+IE G+ W +L+ P L+ WD STYI+ P FFD +TKE A ++ A LL LGDS
Sbjct: 679 KIEMGNKRWNSLEAPDSVLFPWDLKSTYIRCPSFFDKLTKEPIALQAIENAHVLLYLGDS 738
Query: 71 VTTDHISPAGSIARNSPAARYLAQRGLTAREFNSYGSRRGNDAVMSRGTFANIRIVNKMA 130
VTTDHISPAGSIARNS AA+YL RGLT REFNSYG+RRGNDAVM+RGTFANI++ NK
Sbjct: 739 VTTDHISPAGSIARNSAAAKYLTNRGLTPREFNSYGARRGNDAVMTRGTFANIKLFNKFI 798
Query: 131 PAPGPKTTHHPSGDVMDIFDAAERYASEDVPLIAIVGKDYGSGSSRDWAAKGPYLLGIKA 190
P PKT H PSG +D+F+AAE Y E +PLI + GK YGSG+SRDWAAKGPYLLG+KA
Sbjct: 799 GKPAPKTIHFPSGQTLDVFEAAELYQKEGIPLIILAGKKYGSGNSRDWAAKGPYLLGVKA 858
Query: 191 VIAESFERIHRSNLVGMGLLPLQFLPGESAATLGLTGAERYDIILPPALAPGQTATVQVD 250
V+AES+E+IH+ +L+G+G+ PLQFLPGE+A +LGL+G E + + P L+PG T +Q
Sbjct: 859 VLAESYEKIHKDHLIGIGIAPLQFLPGENADSLGLSGRETFSLTFPEELSPGITLNIQTS 918
Query: 251 NGTSFQVVVRFDTEVDLTYFKNGGILNYMVRK 282
G F V+ F+ +V++T +K+GG+LN++ RK
Sbjct: 919 TGKVFSVIASFEDDVEITLYKHGGLLNFVARK 950
>M58511-1|AAA69901.1| 963|Homo sapiens iron-responsive
element-binding protein/iron regulatory protein 2
protein.
Length = 963
Score = 355 bits (874), Expect = 8e-98
Identities = 158/272 (58%), Positives = 204/272 (75%)
Query: 11 RIEQGSAAWQALDVPRGRLYSWDANSTYIKKPPFFDGMTKELPAATSVRGARCLLLLGDS 70
+IE G+ W +L+ P L+ WD STYI+ P FFD +TKE A ++ A LL LGDS
Sbjct: 690 KIEMGNKRWNSLEAPDSVLFPWDLKSTYIRCPSFFDKLTKEPIALQAIENAHVLLYLGDS 749
Query: 71 VTTDHISPAGSIARNSPAARYLAQRGLTAREFNSYGSRRGNDAVMSRGTFANIRIVNKMA 130
VTTDHISPAGSIARNS AA+YL RGLT REFNSYG+RRGNDAVM+RGTFANI++ NK
Sbjct: 750 VTTDHISPAGSIARNSAAAKYLTNRGLTPREFNSYGARRGNDAVMTRGTFANIKLFNKFI 809
Query: 131 PAPGPKTTHHPSGDVMDIFDAAERYASEDVPLIAIVGKDYGSGSSRDWAAKGPYLLGIKA 190
P PKT H PSG +D+F+AAE Y E +PLI + GK YGSG+SRDWAAKGPYLLG+KA
Sbjct: 810 GKPAPKTIHFPSGQTLDVFEAAELYQKEGIPLIILAGKKYGSGNSRDWAAKGPYLLGVKA 869
Query: 191 VIAESFERIHRSNLVGMGLLPLQFLPGESAATLGLTGAERYDIILPPALAPGQTATVQVD 250
V+AES+E+IH+ +L+G+G+ PLQFLPGE+A +LGL+G E + + P L+PG T +Q
Sbjct: 870 VLAESYEKIHKDHLIGIGIAPLQFLPGENADSLGLSGRETFSLTFPEELSPGITLNIQTS 929
Query: 251 NGTSFQVVVRFDTEVDLTYFKNGGILNYMVRK 282
G F V+ F+ +V++T +K+GG+LN++ RK
Sbjct: 930 TGKVFSVIASFEDDVEITLYKHGGLLNFVARK 961
>DQ496102-1|ABF47091.1| 963|Homo sapiens iron-responsive element
binding protein 2 protein.
Length = 963
Score = 355 bits (874), Expect = 8e-98
Identities = 158/272 (58%), Positives = 204/272 (75%)
Query: 11 RIEQGSAAWQALDVPRGRLYSWDANSTYIKKPPFFDGMTKELPAATSVRGARCLLLLGDS 70
+IE G+ W +L+ P L+ WD STYI+ P FFD +TKE A ++ A LL LGDS
Sbjct: 690 KIEMGNKRWNSLEAPDSVLFPWDLKSTYIRCPSFFDKLTKEPIALQAIENAHVLLYLGDS 749
Query: 71 VTTDHISPAGSIARNSPAARYLAQRGLTAREFNSYGSRRGNDAVMSRGTFANIRIVNKMA 130
VTTDHISPAGSIARNS AA+YL RGLT REFNSYG+RRGNDAVM+RGTFANI++ NK
Sbjct: 750 VTTDHISPAGSIARNSAAAKYLTNRGLTPREFNSYGARRGNDAVMTRGTFANIKLFNKFI 809
Query: 131 PAPGPKTTHHPSGDVMDIFDAAERYASEDVPLIAIVGKDYGSGSSRDWAAKGPYLLGIKA 190
P PKT H PSG +D+F+AAE Y E +PLI + GK YGSG+SRDWAAKGPYLLG+KA
Sbjct: 810 GKPAPKTIHFPSGQTLDVFEAAELYQKEGIPLIILAGKKYGSGNSRDWAAKGPYLLGVKA 869
Query: 191 VIAESFERIHRSNLVGMGLLPLQFLPGESAATLGLTGAERYDIILPPALAPGQTATVQVD 250
V+AES+E+IH+ +L+G+G+ PLQFLPGE+A +LGL+G E + + P L+PG T +Q
Sbjct: 870 VLAESYEKIHKDHLIGIGIAPLQFLPGENADSLGLSGRETFSLTFPEELSPGITLNIQTS 929
Query: 251 NGTSFQVVVRFDTEVDLTYFKNGGILNYMVRK 282
G F V+ F+ +V++T +K+GG+LN++ RK
Sbjct: 930 TGKVFSVIASFEDDVEITLYKHGGLLNFVARK 961
>BC117483-1|AAI17484.1| 963|Homo sapiens iron-responsive element
binding protein 2 protein.
Length = 963
Score = 355 bits (874), Expect = 8e-98
Identities = 158/272 (58%), Positives = 204/272 (75%)
Query: 11 RIEQGSAAWQALDVPRGRLYSWDANSTYIKKPPFFDGMTKELPAATSVRGARCLLLLGDS 70
+IE G+ W +L+ P L+ WD STYI+ P FFD +TKE A ++ A LL LGDS
Sbjct: 690 KIEMGNKRWNSLEAPDSVLFPWDLKSTYIRCPSFFDKLTKEPIALQAIENAHVLLYLGDS 749
Query: 71 VTTDHISPAGSIARNSPAARYLAQRGLTAREFNSYGSRRGNDAVMSRGTFANIRIVNKMA 130
VTTDHISPAGSIARNS AA+YL RGLT REFNSYG+RRGNDAVM+RGTFANI++ NK
Sbjct: 750 VTTDHISPAGSIARNSAAAKYLTNRGLTPREFNSYGARRGNDAVMTRGTFANIKLFNKFI 809
Query: 131 PAPGPKTTHHPSGDVMDIFDAAERYASEDVPLIAIVGKDYGSGSSRDWAAKGPYLLGIKA 190
P PKT H PSG +D+F+AAE Y E +PLI + GK YGSG+SRDWAAKGPYLLG+KA
Sbjct: 810 GKPAPKTIHFPSGQTLDVFEAAELYQKEGIPLIILAGKKYGSGNSRDWAAKGPYLLGVKA 869
Query: 191 VIAESFERIHRSNLVGMGLLPLQFLPGESAATLGLTGAERYDIILPPALAPGQTATVQVD 250
V+AES+E+IH+ +L+G+G+ PLQFLPGE+A +LGL+G E + + P L+PG T +Q
Sbjct: 870 VLAESYEKIHKDHLIGIGIAPLQFLPGENADSLGLSGRETFSLTFPEELSPGITLNIQTS 929
Query: 251 NGTSFQVVVRFDTEVDLTYFKNGGILNYMVRK 282
G F V+ F+ +V++T +K+GG+LN++ RK
Sbjct: 930 TGKVFSVIASFEDDVEITLYKHGGLLNFVARK 961
>BC117481-1|AAI17482.1| 963|Homo sapiens iron-responsive element
binding protein 2 protein.
Length = 963
Score = 355 bits (874), Expect = 8e-98
Identities = 158/272 (58%), Positives = 204/272 (75%)
Query: 11 RIEQGSAAWQALDVPRGRLYSWDANSTYIKKPPFFDGMTKELPAATSVRGARCLLLLGDS 70
+IE G+ W +L+ P L+ WD STYI+ P FFD +TKE A ++ A LL LGDS
Sbjct: 690 KIEMGNKRWNSLEAPDSVLFPWDLKSTYIRCPSFFDKLTKEPIALQAIENAHVLLYLGDS 749
Query: 71 VTTDHISPAGSIARNSPAARYLAQRGLTAREFNSYGSRRGNDAVMSRGTFANIRIVNKMA 130
VTTDHISPAGSIARNS AA+YL RGLT REFNSYG+RRGNDAVM+RGTFANI++ NK
Sbjct: 750 VTTDHISPAGSIARNSAAAKYLTNRGLTPREFNSYGARRGNDAVMTRGTFANIKLFNKFI 809
Query: 131 PAPGPKTTHHPSGDVMDIFDAAERYASEDVPLIAIVGKDYGSGSSRDWAAKGPYLLGIKA 190
P PKT H PSG +D+F+AAE Y E +PLI + GK YGSG+SRDWAAKGPYLLG+KA
Sbjct: 810 GKPAPKTIHFPSGQTLDVFEAAELYQKEGIPLIILAGKKYGSGNSRDWAAKGPYLLGVKA 869
Query: 191 VIAESFERIHRSNLVGMGLLPLQFLPGESAATLGLTGAERYDIILPPALAPGQTATVQVD 250
V+AES+E+IH+ +L+G+G+ PLQFLPGE+A +LGL+G E + + P L+PG T +Q
Sbjct: 870 VLAESYEKIHKDHLIGIGIAPLQFLPGENADSLGLSGRETFSLTFPEELSPGITLNIQTS 929
Query: 251 NGTSFQVVVRFDTEVDLTYFKNGGILNYMVRK 282
G F V+ F+ +V++T +K+GG+LN++ RK
Sbjct: 930 TGKVFSVIASFEDDVEITLYKHGGLLNFVARK 961
>AL133439-1|CAB62825.1| 117|Homo sapiens IRP2; iron-responsive
element-binding protein/iron regulatory protein 2
protein.
Length = 117
Score = 152 bits (369), Expect = 1e-36
Identities = 63/115 (54%), Positives = 90/115 (78%)
Query: 168 KDYGSGSSRDWAAKGPYLLGIKAVIAESFERIHRSNLVGMGLLPLQFLPGESAATLGLTG 227
K YGSG+SRDWAAKGPYLLG+KAV+AES+E+IH+ +L+G+G+ PLQFLPGE+A +LGL+G
Sbjct: 1 KKYGSGNSRDWAAKGPYLLGVKAVLAESYEKIHKDHLIGIGIAPLQFLPGENADSLGLSG 60
Query: 228 AERYDIILPPALAPGQTATVQVDNGTSFQVVVRFDTEVDLTYFKNGGILNYMVRK 282
E + + P L+PG T +Q G F V+ F+ +V++T +K+GG+LN++ RK
Sbjct: 61 RETFSLTFPEELSPGITLNIQTSTGKVFSVIASFEDDVEITLYKHGGLLNFVARK 115
>AB209480-1|BAD92717.1| 781|Homo sapiens aconitase 1 variant
protein.
Length = 781
Score = 113 bits (273), Expect = 5e-25
Identities = 54/96 (56%), Positives = 67/96 (69%)
Query: 1 IPVSSVQVYARIEQGSAAWQALDVPRGRLYSWDANSTYIKKPPFFDGMTKELPAATSVRG 60
IP +VY +IE + +W AL P +L+ W++ STYIK PPFF+ +T +L S+
Sbjct: 641 IPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTLDLQPPKSIVD 700
Query: 61 ARCLLLLGDSVTTDHISPAGSIARNSPAARYLAQRG 96
A LL LGDSVTTDHISPAG+IARNSPAARYL RG
Sbjct: 701 AYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRG 736
>U87939-1|AAC39921.1| 780|Homo sapiens aconitate hydratase protein.
Length = 780
Score = 63.7 bits (148), Expect = 7e-10
Identities = 43/133 (32%), Positives = 65/133 (48%), Gaps = 5/133 (3%)
Query: 150 DAAERYASEDVPLIAIVGKDYGSGSSRDWAAKGPYLLGIKAVIAESFERIHRSNLVGMGL 209
D A Y + + I ++YG GSSR+ AA P LG +A+I +SF RIH +NL GL
Sbjct: 645 DTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGL 704
Query: 210 LPLQFLPGESAATLGLTGAERYDIILPPALAPGQ--TATVQVDNGTSFQVVVRFD-TEVD 266
LPL F + A + ++ I PG+ ++ NGT +++ E
Sbjct: 705 LPLTF--ADPADYNKIHPVDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQ 762
Query: 267 LTYFKNGGILNYM 279
+ +F+ G LN M
Sbjct: 763 IEWFRAGSALNRM 775
>U80040-1|AAB38416.1| 780|Homo sapiens mitochondrial aconitase
protein.
Length = 780
Score = 63.7 bits (148), Expect = 7e-10
Identities = 43/133 (32%), Positives = 65/133 (48%), Gaps = 5/133 (3%)
Query: 150 DAAERYASEDVPLIAIVGKDYGSGSSRDWAAKGPYLLGIKAVIAESFERIHRSNLVGMGL 209
D A Y + + I ++YG GSSR+ AA P LG +A+I +SF RIH +NL GL
Sbjct: 645 DTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGL 704
Query: 210 LPLQFLPGESAATLGLTGAERYDIILPPALAPGQ--TATVQVDNGTSFQVVVRFD-TEVD 266
LPL F + A + ++ I PG+ ++ NGT +++ E
Sbjct: 705 LPLTF--ADPADYNKIHPVDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQ 762
Query: 267 LTYFKNGGILNYM 279
+ +F+ G LN M
Sbjct: 763 IEWFRAGSALNRM 775
>CR536568-1|CAG38805.1| 780|Homo sapiens ACO2 protein.
Length = 780
Score = 63.7 bits (148), Expect = 7e-10
Identities = 43/133 (32%), Positives = 65/133 (48%), Gaps = 5/133 (3%)
Query: 150 DAAERYASEDVPLIAIVGKDYGSGSSRDWAAKGPYLLGIKAVIAESFERIHRSNLVGMGL 209
D A Y + + I ++YG GSSR+ AA P LG +A+I +SF RIH +NL GL
Sbjct: 645 DTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGL 704
Query: 210 LPLQFLPGESAATLGLTGAERYDIILPPALAPGQ--TATVQVDNGTSFQVVVRFD-TEVD 266
LPL F + A + ++ I PG+ ++ NGT +++ E
Sbjct: 705 LPLTF--ADPADYNKIHPVDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQ 762
Query: 267 LTYFKNGGILNYM 279
+ +F+ G LN M
Sbjct: 763 IEWFRAGSALNRM 775
>CR456365-1|CAG30251.1| 780|Homo sapiens ACO2 protein.
Length = 780
Score = 63.7 bits (148), Expect = 7e-10
Identities = 43/133 (32%), Positives = 65/133 (48%), Gaps = 5/133 (3%)
Query: 150 DAAERYASEDVPLIAIVGKDYGSGSSRDWAAKGPYLLGIKAVIAESFERIHRSNLVGMGL 209
D A Y + + I ++YG GSSR+ AA P LG +A+I +SF RIH +NL GL
Sbjct: 645 DTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGL 704
Query: 210 LPLQFLPGESAATLGLTGAERYDIILPPALAPGQ--TATVQVDNGTSFQVVVRFD-TEVD 266
LPL F + A + ++ I PG+ ++ NGT +++ E
Sbjct: 705 LPLTF--ADPADYNKIHPVDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQ 762
Query: 267 LTYFKNGGILNYM 279
+ +F+ G LN M
Sbjct: 763 IEWFRAGSALNRM 775
>BC026196-1|AAH26196.1| 780|Homo sapiens aconitase 2, mitochondrial
protein.
Length = 780
Score = 63.7 bits (148), Expect = 7e-10
Identities = 43/133 (32%), Positives = 65/133 (48%), Gaps = 5/133 (3%)
Query: 150 DAAERYASEDVPLIAIVGKDYGSGSSRDWAAKGPYLLGIKAVIAESFERIHRSNLVGMGL 209
D A Y + + I ++YG GSSR+ AA P LG +A+I +SF RIH +NL GL
Sbjct: 645 DTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGL 704
Query: 210 LPLQFLPGESAATLGLTGAERYDIILPPALAPGQ--TATVQVDNGTSFQVVVRFD-TEVD 266
LPL F + A + ++ I PG+ ++ NGT +++ E
Sbjct: 705 LPLTF--ADPADYNKIHPVDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQ 762
Query: 267 LTYFKNGGILNYM 279
+ +F+ G LN M
Sbjct: 763 IEWFRAGSALNRM 775
>BC014092-1|AAH14092.1| 780|Homo sapiens aconitase 2, mitochondrial
protein.
Length = 780
Score = 63.7 bits (148), Expect = 7e-10
Identities = 43/133 (32%), Positives = 65/133 (48%), Gaps = 5/133 (3%)
Query: 150 DAAERYASEDVPLIAIVGKDYGSGSSRDWAAKGPYLLGIKAVIAESFERIHRSNLVGMGL 209
D A Y + + I ++YG GSSR+ AA P LG +A+I +SF RIH +NL GL
Sbjct: 645 DTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGL 704
Query: 210 LPLQFLPGESAATLGLTGAERYDIILPPALAPGQ--TATVQVDNGTSFQVVVRFD-TEVD 266
LPL F + A + ++ I PG+ ++ NGT +++ E
Sbjct: 705 LPLTF--ADPADYNKIHPVDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQ 762
Query: 267 LTYFKNGGILNYM 279
+ +F+ G LN M
Sbjct: 763 IEWFRAGSALNRM 775
>AL023553-4|CAM28239.1| 805|Homo sapiens aconitase 2, mitochondrial
protein.
Length = 805
Score = 63.7 bits (148), Expect = 7e-10
Identities = 43/133 (32%), Positives = 65/133 (48%), Gaps = 5/133 (3%)
Query: 150 DAAERYASEDVPLIAIVGKDYGSGSSRDWAAKGPYLLGIKAVIAESFERIHRSNLVGMGL 209
D A Y + + I ++YG GSSR+ AA P LG +A+I +SF RIH +NL GL
Sbjct: 670 DTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGL 729
Query: 210 LPLQFLPGESAATLGLTGAERYDIILPPALAPGQ--TATVQVDNGTSFQVVVRFD-TEVD 266
LPL F + A + ++ I PG+ ++ NGT +++ E
Sbjct: 730 LPLTF--ADPADYNKIHPVDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQ 787
Query: 267 LTYFKNGGILNYM 279
+ +F+ G LN M
Sbjct: 788 IEWFRAGSALNRM 800
>AL023553-3|CAI20278.1| 780|Homo sapiens aconitase 2, mitochondrial
protein.
Length = 780
Score = 63.7 bits (148), Expect = 7e-10
Identities = 43/133 (32%), Positives = 65/133 (48%), Gaps = 5/133 (3%)
Query: 150 DAAERYASEDVPLIAIVGKDYGSGSSRDWAAKGPYLLGIKAVIAESFERIHRSNLVGMGL 209
D A Y + + I ++YG GSSR+ AA P LG +A+I +SF RIH +NL GL
Sbjct: 645 DTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGL 704
Query: 210 LPLQFLPGESAATLGLTGAERYDIILPPALAPGQ--TATVQVDNGTSFQVVVRFD-TEVD 266
LPL F + A + ++ I PG+ ++ NGT +++ E
Sbjct: 705 LPLTF--ADPADYNKIHPVDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQ 762
Query: 267 LTYFKNGGILNYM 279
+ +F+ G LN M
Sbjct: 763 IEWFRAGSALNRM 775
>AL008582-4|CAM25244.1| 805|Homo sapiens aconitase 2, mitochondrial
protein.
Length = 805
Score = 63.7 bits (148), Expect = 7e-10
Identities = 43/133 (32%), Positives = 65/133 (48%), Gaps = 5/133 (3%)
Query: 150 DAAERYASEDVPLIAIVGKDYGSGSSRDWAAKGPYLLGIKAVIAESFERIHRSNLVGMGL 209
D A Y + + I ++YG GSSR+ AA P LG +A+I +SF RIH +NL GL
Sbjct: 670 DTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGL 729
Query: 210 LPLQFLPGESAATLGLTGAERYDIILPPALAPGQ--TATVQVDNGTSFQVVVRFD-TEVD 266
LPL F + A + ++ I PG+ ++ NGT +++ E
Sbjct: 730 LPLTF--ADPADYNKIHPVDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQ 787
Query: 267 LTYFKNGGILNYM 279
+ +F+ G LN M
Sbjct: 788 IEWFRAGSALNRM 800
>AL008582-3|CAI17931.1| 780|Homo sapiens aconitase 2, mitochondrial
protein.
Length = 780
Score = 63.7 bits (148), Expect = 7e-10
Identities = 43/133 (32%), Positives = 65/133 (48%), Gaps = 5/133 (3%)
Query: 150 DAAERYASEDVPLIAIVGKDYGSGSSRDWAAKGPYLLGIKAVIAESFERIHRSNLVGMGL 209
D A Y + + I ++YG GSSR+ AA P LG +A+I +SF RIH +NL GL
Sbjct: 645 DTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGL 704
Query: 210 LPLQFLPGESAATLGLTGAERYDIILPPALAPGQ--TATVQVDNGTSFQVVVRFD-TEVD 266
LPL F + A + ++ I PG+ ++ NGT +++ E
Sbjct: 705 LPLTF--ADPADYNKIHPVDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQ 762
Query: 267 LTYFKNGGILNYM 279
+ +F+ G LN M
Sbjct: 763 IEWFRAGSALNRM 775
>AF093096-1|AAD19351.2| 780|Homo sapiens aconitase protein.
Length = 780
Score = 63.7 bits (148), Expect = 7e-10
Identities = 43/133 (32%), Positives = 65/133 (48%), Gaps = 5/133 (3%)
Query: 150 DAAERYASEDVPLIAIVGKDYGSGSSRDWAAKGPYLLGIKAVIAESFERIHRSNLVGMGL 209
D A Y + + I ++YG GSSR+ AA P LG +A+I +SF RIH +NL GL
Sbjct: 645 DTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGL 704
Query: 210 LPLQFLPGESAATLGLTGAERYDIILPPALAPGQ--TATVQVDNGTSFQVVVRFD-TEVD 266
LPL F + A + ++ I PG+ ++ NGT +++ E
Sbjct: 705 LPLTF--ADPADYNKIHPVDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQ 762
Query: 267 LTYFKNGGILNYM 279
+ +F+ G LN M
Sbjct: 763 IEWFRAGSALNRM 775
>AF086790-1|AAC35557.1| 600|Homo sapiens aconitase precursor
protein.
Length = 600
Score = 56.4 bits (130), Expect = 1e-07
Identities = 41/133 (30%), Positives = 65/133 (48%), Gaps = 6/133 (4%)
Query: 150 DAAERYASEDVPLIAIVGKDYGSGSSRDWAAKGPYLLGIKAVIAESFERIHRSNLVGMGL 209
D A Y + + I ++YG GSSR+ AA P LG +A+I +SF RIH + + GL
Sbjct: 466 DTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHET-IKKQGL 524
Query: 210 LPLQFLPGESAATLGLTGAERYDIILPPALAPGQ--TATVQVDNGTSFQVVVRFD-TEVD 266
LPL F + + + ++ I APG+ ++ NGT +++ E
Sbjct: 525 LPLTF--ADPSDYNKIHPVDKLTIQGLKDFAPGKPLKCIIKHPNGTQETILLNHTFNETQ 582
Query: 267 LTYFKNGGILNYM 279
+ +F+ G LN M
Sbjct: 583 IEWFRAGSALNRM 595
>AB209403-1|BAD92640.1| 802|Homo sapiens iron-responsive element
binding protein 2 variant protein.
Length = 802
Score = 46.4 bits (105), Expect = 1e-04
Identities = 18/40 (45%), Positives = 25/40 (62%)
Query: 11 RIEQGSAAWQALDVPRGRLYSWDANSTYIKKPPFFDGMTK 50
+IE G+ W +L+ P L+ WD STYI+ P FFD + K
Sbjct: 722 KIEMGNKRWNSLEAPDSVLFPWDLKSTYIRCPSFFDKLPK 761
>BC112897-1|AAI12898.1| 906|Homo sapiens KIAA0350 protein protein.
Length = 906
Score = 31.5 bits (68), Expect = 3.5
Identities = 13/40 (32%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 102 FNSYGSRRGNDAVMSRGTFANI-RIVNKMAPAPGPKTTHH 140
F G R +D + R FA++ ++ + AP P P+ HH
Sbjct: 837 FYDQGRRGSSDPTVQRSVFASVDKVPGEPAPRPAPQLVHH 876
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.135 0.398
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 43,480,510
Number of Sequences: 224733
Number of extensions: 1851937
Number of successful extensions: 3109
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 3072
Number of HSP's gapped (non-prelim): 38
length of query: 284
length of database: 73,234,838
effective HSP length: 89
effective length of query: 195
effective length of database: 53,233,601
effective search space: 10380552195
effective search space used: 10380552195
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 65 (30.3 bits)
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