Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001725-TA|BGIBMGA001725-PA|IPR001030|Aconitate
hydratase, N-terminal
(419 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Z11559-1|CAA77651.1| 889|Homo sapiens iron regulatory factor pr... 525 e-148
DQ496106-1|ABF47095.1| 889|Homo sapiens aconitase 1, soluble pr... 525 e-148
BC018103-1|AAH18103.1| 889|Homo sapiens aconitase 1, soluble pr... 525 e-148
AL161783-3|CAH72599.1| 434|Homo sapiens aconitase 1, soluble pr... 525 e-148
AL161783-2|CAH72598.1| 889|Homo sapiens aconitase 1, soluble pr... 525 e-148
AB209480-1|BAD92717.1| 781|Homo sapiens aconitase 1 variant pro... 525 e-148
M58510-1|AAA69900.1| 816|Homo sapiens iron-responsive regulator... 473 e-133
AF261088-1|AAF99681.1| 790|Homo sapiens iron regulatory protein... 427 e-119
DQ496102-1|ABF47091.1| 963|Homo sapiens iron-responsive element... 308 2e-83
BC117483-1|AAI17484.1| 963|Homo sapiens iron-responsive element... 308 2e-83
BC117481-1|AAI17482.1| 963|Homo sapiens iron-responsive element... 308 2e-83
AB209403-1|BAD92640.1| 802|Homo sapiens iron-responsive element... 308 2e-83
M58511-1|AAA69901.1| 963|Homo sapiens iron-responsive element-b... 305 1e-82
U20180-1|AAA79926.1| 952|Homo sapiens iron-regulatory protein 2... 304 4e-82
BC017880-1|AAH17880.1| 343|Homo sapiens IREB2 protein protein. 169 2e-41
CR536568-1|CAG38805.1| 780|Homo sapiens ACO2 protein. 113 1e-24
U87939-1|AAC39921.1| 780|Homo sapiens aconitate hydratase protein. 113 1e-24
U80040-1|AAB38416.1| 780|Homo sapiens mitochondrial aconitase p... 113 1e-24
CR456365-1|CAG30251.1| 780|Homo sapiens ACO2 protein. 113 1e-24
BC014092-1|AAH14092.1| 780|Homo sapiens aconitase 2, mitochondr... 113 1e-24
AL023553-3|CAI20278.1| 780|Homo sapiens aconitase 2, mitochondr... 113 1e-24
AL008582-3|CAI17931.1| 780|Homo sapiens aconitase 2, mitochondr... 113 1e-24
AF093096-1|AAD19351.2| 780|Homo sapiens aconitase protein. 113 1e-24
BC026196-1|AAH26196.1| 780|Homo sapiens aconitase 2, mitochondr... 109 2e-23
AL023553-4|CAM28239.1| 805|Homo sapiens aconitase 2, mitochondr... 90 1e-17
AL008582-4|CAM25244.1| 805|Homo sapiens aconitase 2, mitochondr... 90 1e-17
BX538349-1|CAD98144.1| 84|Homo sapiens hypothetical protein pr... 89 2e-17
AF086790-1|AAC35557.1| 600|Homo sapiens aconitase precursor pro... 87 8e-17
>Z11559-1|CAA77651.1| 889|Homo sapiens iron regulatory factor
protein.
Length = 889
Score = 525 bits (1295), Expect = e-148
Identities = 252/397 (63%), Positives = 310/397 (78%), Gaps = 4/397 (1%)
Query: 5 TNPYQKLLKTIEINGSTYTYYDVSAL-GPKYDRLPFSIRVLLESCVRNCDNFQVLEKDVS 63
+NP+ L + ++ +++++ L +Y RLPFSIRVLLE+ +RNCD F V ++D+
Sbjct: 2 SNPFAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDIE 61
Query: 64 NVLDWESKQGNEESVEIAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDRINPICP 123
N+L W Q +++E+ FKPARVILQD TGVPAVVDFAAMRDAVK LGGDP++INP+CP
Sbjct: 62 NILHWNVTQ--HKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCP 119
Query: 124 ADLVIDHSVQVDFARTPDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPGSGIVHQ 183
ADLVIDHS+QVDF R D+L KNQDLEF RN+ERF+FLKWG+QAF NM I+PPGSGI+HQ
Sbjct: 120 ADLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQ 179
Query: 184 VNLEYLARVVFTGP-LLHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQAISMLL 242
VNLEYLARVVF +PDS+VGTDSHTTMI+ IEAEAVMLGQ ISM+L
Sbjct: 180 VNLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVL 239
Query: 243 PKVVGYKLVGELNPLATSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRATVANM 302
P+V+GY+L+G+ +PL TSTD+VLTITKHLR +GVVGKFVEFFGPGV LSIADRAT+ANM
Sbjct: 240 PQVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANM 299
Query: 303 CPEFGATLAHFPVDARSLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPVFSEVV 362
CPE+GAT A FPVD S+ YL QT R +EK+ I+ YL+A FRD+ +P QDP F++VV
Sbjct: 300 CPEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVV 359
Query: 363 ELDLGDVVTSVSGPKRPQDRVSVAIMKKDFQDCLTNK 399
ELDL VV SGPKRPQD+V+V+ MKKDF+ CL K
Sbjct: 360 ELDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAK 396
>DQ496106-1|ABF47095.1| 889|Homo sapiens aconitase 1, soluble
protein.
Length = 889
Score = 525 bits (1295), Expect = e-148
Identities = 252/397 (63%), Positives = 310/397 (78%), Gaps = 4/397 (1%)
Query: 5 TNPYQKLLKTIEINGSTYTYYDVSAL-GPKYDRLPFSIRVLLESCVRNCDNFQVLEKDVS 63
+NP+ L + ++ +++++ L +Y RLPFSIRVLLE+ +RNCD F V ++D+
Sbjct: 2 SNPFAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDIE 61
Query: 64 NVLDWESKQGNEESVEIAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDRINPICP 123
N+L W Q +++E+ FKPARVILQD TGVPAVVDFAAMRDAVK LGGDP++INP+CP
Sbjct: 62 NILHWNVTQ--HKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCP 119
Query: 124 ADLVIDHSVQVDFARTPDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPGSGIVHQ 183
ADLVIDHS+QVDF R D+L KNQDLEF RN+ERF+FLKWG+QAF NM I+PPGSGI+HQ
Sbjct: 120 ADLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQ 179
Query: 184 VNLEYLARVVFTGP-LLHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQAISMLL 242
VNLEYLARVVF +PDS+VGTDSHTTMI+ IEAEAVMLGQ ISM+L
Sbjct: 180 VNLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVL 239
Query: 243 PKVVGYKLVGELNPLATSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRATVANM 302
P+V+GY+L+G+ +PL TSTD+VLTITKHLR +GVVGKFVEFFGPGV LSIADRAT+ANM
Sbjct: 240 PQVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANM 299
Query: 303 CPEFGATLAHFPVDARSLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPVFSEVV 362
CPE+GAT A FPVD S+ YL QT R +EK+ I+ YL+A FRD+ +P QDP F++VV
Sbjct: 300 CPEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVV 359
Query: 363 ELDLGDVVTSVSGPKRPQDRVSVAIMKKDFQDCLTNK 399
ELDL VV SGPKRPQD+V+V+ MKKDF+ CL K
Sbjct: 360 ELDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAK 396
>BC018103-1|AAH18103.1| 889|Homo sapiens aconitase 1, soluble
protein.
Length = 889
Score = 525 bits (1295), Expect = e-148
Identities = 252/397 (63%), Positives = 310/397 (78%), Gaps = 4/397 (1%)
Query: 5 TNPYQKLLKTIEINGSTYTYYDVSAL-GPKYDRLPFSIRVLLESCVRNCDNFQVLEKDVS 63
+NP+ L + ++ +++++ L +Y RLPFSIRVLLE+ +RNCD F V ++D+
Sbjct: 2 SNPFAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDIE 61
Query: 64 NVLDWESKQGNEESVEIAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDRINPICP 123
N+L W Q +++E+ FKPARVILQD TGVPAVVDFAAMRDAVK LGGDP++INP+CP
Sbjct: 62 NILHWNVTQ--HKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCP 119
Query: 124 ADLVIDHSVQVDFARTPDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPGSGIVHQ 183
ADLVIDHS+QVDF R D+L KNQDLEF RN+ERF+FLKWG+QAF NM I+PPGSGI+HQ
Sbjct: 120 ADLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQ 179
Query: 184 VNLEYLARVVFTGP-LLHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQAISMLL 242
VNLEYLARVVF +PDS+VGTDSHTTMI+ IEAEAVMLGQ ISM+L
Sbjct: 180 VNLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVL 239
Query: 243 PKVVGYKLVGELNPLATSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRATVANM 302
P+V+GY+L+G+ +PL TSTD+VLTITKHLR +GVVGKFVEFFGPGV LSIADRAT+ANM
Sbjct: 240 PQVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANM 299
Query: 303 CPEFGATLAHFPVDARSLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPVFSEVV 362
CPE+GAT A FPVD S+ YL QT R +EK+ I+ YL+A FRD+ +P QDP F++VV
Sbjct: 300 CPEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVV 359
Query: 363 ELDLGDVVTSVSGPKRPQDRVSVAIMKKDFQDCLTNK 399
ELDL VV SGPKRPQD+V+V+ MKKDF+ CL K
Sbjct: 360 ELDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAK 396
>AL161783-3|CAH72599.1| 434|Homo sapiens aconitase 1, soluble
protein.
Length = 434
Score = 525 bits (1295), Expect = e-148
Identities = 252/397 (63%), Positives = 310/397 (78%), Gaps = 4/397 (1%)
Query: 5 TNPYQKLLKTIEINGSTYTYYDVSAL-GPKYDRLPFSIRVLLESCVRNCDNFQVLEKDVS 63
+NP+ L + ++ +++++ L +Y RLPFSIRVLLE+ +RNCD F V ++D+
Sbjct: 2 SNPFAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDIE 61
Query: 64 NVLDWESKQGNEESVEIAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDRINPICP 123
N+L W Q +++E+ FKPARVILQD TGVPAVVDFAAMRDAVK LGGDP++INP+CP
Sbjct: 62 NILHWNVTQ--HKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCP 119
Query: 124 ADLVIDHSVQVDFARTPDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPGSGIVHQ 183
ADLVIDHS+QVDF R D+L KNQDLEF RN+ERF+FLKWG+QAF NM I+PPGSGI+HQ
Sbjct: 120 ADLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQ 179
Query: 184 VNLEYLARVVFTGP-LLHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQAISMLL 242
VNLEYLARVVF +PDS+VGTDSHTTMI+ IEAEAVMLGQ ISM+L
Sbjct: 180 VNLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVL 239
Query: 243 PKVVGYKLVGELNPLATSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRATVANM 302
P+V+GY+L+G+ +PL TSTD+VLTITKHLR +GVVGKFVEFFGPGV LSIADRAT+ANM
Sbjct: 240 PQVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANM 299
Query: 303 CPEFGATLAHFPVDARSLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPVFSEVV 362
CPE+GAT A FPVD S+ YL QT R +EK+ I+ YL+A FRD+ +P QDP F++VV
Sbjct: 300 CPEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVV 359
Query: 363 ELDLGDVVTSVSGPKRPQDRVSVAIMKKDFQDCLTNK 399
ELDL VV SGPKRPQD+V+V+ MKKDF+ CL K
Sbjct: 360 ELDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAK 396
>AL161783-2|CAH72598.1| 889|Homo sapiens aconitase 1, soluble
protein.
Length = 889
Score = 525 bits (1295), Expect = e-148
Identities = 252/397 (63%), Positives = 310/397 (78%), Gaps = 4/397 (1%)
Query: 5 TNPYQKLLKTIEINGSTYTYYDVSAL-GPKYDRLPFSIRVLLESCVRNCDNFQVLEKDVS 63
+NP+ L + ++ +++++ L +Y RLPFSIRVLLE+ +RNCD F V ++D+
Sbjct: 2 SNPFAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDIE 61
Query: 64 NVLDWESKQGNEESVEIAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDRINPICP 123
N+L W Q +++E+ FKPARVILQD TGVPAVVDFAAMRDAVK LGGDP++INP+CP
Sbjct: 62 NILHWNVTQ--HKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCP 119
Query: 124 ADLVIDHSVQVDFARTPDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPGSGIVHQ 183
ADLVIDHS+QVDF R D+L KNQDLEF RN+ERF+FLKWG+QAF NM I+PPGSGI+HQ
Sbjct: 120 ADLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQ 179
Query: 184 VNLEYLARVVFTGP-LLHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQAISMLL 242
VNLEYLARVVF +PDS+VGTDSHTTMI+ IEAEAVMLGQ ISM+L
Sbjct: 180 VNLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVL 239
Query: 243 PKVVGYKLVGELNPLATSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRATVANM 302
P+V+GY+L+G+ +PL TSTD+VLTITKHLR +GVVGKFVEFFGPGV LSIADRAT+ANM
Sbjct: 240 PQVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANM 299
Query: 303 CPEFGATLAHFPVDARSLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPVFSEVV 362
CPE+GAT A FPVD S+ YL QT R +EK+ I+ YL+A FRD+ +P QDP F++VV
Sbjct: 300 CPEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVV 359
Query: 363 ELDLGDVVTSVSGPKRPQDRVSVAIMKKDFQDCLTNK 399
ELDL VV SGPKRPQD+V+V+ MKKDF+ CL K
Sbjct: 360 ELDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAK 396
>AB209480-1|BAD92717.1| 781|Homo sapiens aconitase 1 variant
protein.
Length = 781
Score = 525 bits (1295), Expect = e-148
Identities = 252/397 (63%), Positives = 310/397 (78%), Gaps = 4/397 (1%)
Query: 5 TNPYQKLLKTIEINGSTYTYYDVSAL-GPKYDRLPFSIRVLLESCVRNCDNFQVLEKDVS 63
+NP+ L + ++ +++++ L +Y RLPFSIRVLLE+ +RNCD F V ++D+
Sbjct: 38 SNPFAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDIE 97
Query: 64 NVLDWESKQGNEESVEIAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDRINPICP 123
N+L W Q +++E+ FKPARVILQD TGVPAVVDFAAMRDAVK LGGDP++INP+CP
Sbjct: 98 NILHWNVTQ--HKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCP 155
Query: 124 ADLVIDHSVQVDFARTPDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPGSGIVHQ 183
ADLVIDHS+QVDF R D+L KNQDLEF RN+ERF+FLKWG+QAF NM I+PPGSGI+HQ
Sbjct: 156 ADLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQ 215
Query: 184 VNLEYLARVVFTGP-LLHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQAISMLL 242
VNLEYLARVVF +PDS+VGTDSHTTMI+ IEAEAVMLGQ ISM+L
Sbjct: 216 VNLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVL 275
Query: 243 PKVVGYKLVGELNPLATSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRATVANM 302
P+V+GY+L+G+ +PL TSTD+VLTITKHLR +GVVGKFVEFFGPGV LSIADRAT+ANM
Sbjct: 276 PQVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANM 335
Query: 303 CPEFGATLAHFPVDARSLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPVFSEVV 362
CPE+GAT A FPVD S+ YL QT R +EK+ I+ YL+A FRD+ +P QDP F++VV
Sbjct: 336 CPEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVV 395
Query: 363 ELDLGDVVTSVSGPKRPQDRVSVAIMKKDFQDCLTNK 399
ELDL VV SGPKRPQD+V+V+ MKKDF+ CL K
Sbjct: 396 ELDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAK 432
>M58510-1|AAA69900.1| 816|Homo sapiens iron-responsive regulatory
protein/iron regulatory protein 1 protein.
Length = 816
Score = 473 bits (1167), Expect = e-133
Identities = 225/323 (69%), Positives = 264/323 (81%), Gaps = 1/323 (0%)
Query: 78 VEIAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDRINPICPADLVIDHSVQVDFA 137
+E+ FKPARVILQD TGVPAVVDFAAMRDAVK LGGDP++INP+CPADLVIDHS+QVDF
Sbjct: 1 IEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCPADLVIDHSIQVDFN 60
Query: 138 RTPDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPGSGIVHQVNLEYLARVVFTGP 197
R D+L KNQDLEF RN+ERF+FLKWG+QAF NM I+PPGSGI+HQVNLEYLARVVF
Sbjct: 61 RRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQVNLEYLARVVFDQD 120
Query: 198 -LLHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQAISMLLPKVVGYKLVGELNP 256
+PDS+VGTDSHTTMI+ IEAEAVMLGQ ISM+LP+V+GY+L+G+ +P
Sbjct: 121 GYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVLPQVIGYRLMGKPHP 180
Query: 257 LATSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRATVANMCPEFGATLAHFPVD 316
L TSTD+VLTITKHLR +GVVGKFVEFFGPGV LSIADRAT+ANMCPE+GAT A FPVD
Sbjct: 181 LVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMCPEYGATAAFFPVD 240
Query: 317 ARSLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPVFSEVVELDLGDVVTSVSGP 376
S+ YL QT R +EK+ I+ YL+A FRD+ +P QDP F++VVELDL VV SGP
Sbjct: 241 EVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVVELDLKTVVPCCSGP 300
Query: 377 KRPQDRVSVAIMKKDFQDCLTNK 399
KRPQD+V+V+ MKKDF+ CL K
Sbjct: 301 KRPQDKVAVSDMKKDFESCLGAK 323
>AF261088-1|AAF99681.1| 790|Homo sapiens iron regulatory protein 1
protein.
Length = 790
Score = 427 bits (1053), Expect = e-119
Identities = 203/297 (68%), Positives = 240/297 (80%), Gaps = 1/297 (0%)
Query: 104 MRDAVKDLGGDPDRINPICPADLVIDHSVQVDFARTPDALNKNQDLEFVRNKERFQFLKW 163
MRDAVK LGGDP++INP+CPADLVIDHS+QVDF R D+L KNQDLEF RN+ERF+FLKW
Sbjct: 1 MRDAVKKLGGDPEKINPVCPADLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKW 60
Query: 164 GAQAFDNMLIVPPGSGIVHQVNLEYLARVVFTGP-LLHPDSVVGTDSHTTMINXXXXXXX 222
G+QAF NM I+PPGSGI+HQVNLEYLARVVF +PDS+VGTDSHTTMI+
Sbjct: 61 GSQAFHNMRIIPPGSGIIHQVNLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGW 120
Query: 223 XXXXIEAEAVMLGQAISMLLPKVVGYKLVGELNPLATSTDLVLTITKHLRSLGVVGKFVE 282
IEAEAVMLGQ ISM+LP+V+GY+L+G+ +PL TSTD+VLTITKHLR +GVVGKFVE
Sbjct: 121 GVGGIEAEAVMLGQPISMVLPQVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVE 180
Query: 283 FFGPGVGALSIADRATVANMCPEFGATLAHFPVDARSLEYLHQTNRPKEKIDVIESYLRA 342
FFGPGV LSIADRAT+ANMCPE+GAT A FPVD S+ YL QT R +EK+ I+ YL+A
Sbjct: 181 FFGPGVAQLSIADRATIANMCPEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQA 240
Query: 343 TKQFRDYTNPEQDPVFSEVVELDLGDVVTSVSGPKRPQDRVSVAIMKKDFQDCLTNK 399
FRD+ +P QDP F++VVELDL VV SGPKRPQD+V+V+ MKKDF+ CL K
Sbjct: 241 VGMFRDFNDPSQDPDFTQVVELDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAK 297
>DQ496102-1|ABF47091.1| 963|Homo sapiens iron-responsive element
binding protein 2 protein.
Length = 963
Score = 308 bits (756), Expect = 2e-83
Identities = 145/261 (55%), Positives = 187/261 (71%), Gaps = 1/261 (0%)
Query: 140 PDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPGSGIVHQVNLEYLARVVFTGP-L 198
P+ + KNQ++EF RN+ER QF KW ++ F N+ ++PPG+G+ HQ+NLEYL+RVVF L
Sbjct: 211 PETVLKNQEVEFGRNRERLQFFKWSSRVFKNVAVIPPGTGMAHQINLEYLSRVVFEEKDL 270
Query: 199 LHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQAISMLLPKVVGYKLVGELNPLA 258
L PDSVVGTDSH TM+N IE EAVMLG +S+ LP+VVG +L G NP
Sbjct: 271 LFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVSLTLPEVVGCELTGSSNPFV 330
Query: 259 TSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRATVANMCPEFGATLAHFPVDAR 318
TS D+VL ITKHLR +GV GKFVEFFG GV LSI DR T+ANMCPE+GA L+ FPVD
Sbjct: 331 TSIDVVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPVDNV 390
Query: 319 SLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPVFSEVVELDLGDVVTSVSGPKR 378
+L++L T K K++ +E+YL+A K FR+ N +P +S+V++++L +V SVSGPKR
Sbjct: 391 TLKHLEHTGFSKAKLESMETYLKAVKLFRNDQNSSGEPEYSQVIQINLNSIVPSVSGPKR 450
Query: 379 PQDRVSVAIMKKDFQDCLTNK 399
PQDRV+V MK DFQ CL K
Sbjct: 451 PQDRVAVTDMKSDFQACLNEK 471
Score = 169 bits (410), Expect = 2e-41
Identities = 75/131 (57%), Positives = 105/131 (80%), Gaps = 4/131 (3%)
Query: 8 YQKLLKTIEINGSTYTYYDVSALGPKYDRLPFSIRVLLESCVRNCDNFQVLEKDVSNVLD 67
++ L++T+ + S ++DVS LG KYD LP+SIRVLLE+ VRNCD F + ++DV N+LD
Sbjct: 10 FEYLIETLN-DSSHKKFFDVSKLGTKYDVLPYSIRVLLEAAVRNCDGFLMKKEDVMNILD 68
Query: 68 WESKQGNEESVEIAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDRINPICPADLV 127
W++KQ N VE+ F PARV+LQD TG+PA+VDFAAMR+AVK LGGDP++++P CP DL
Sbjct: 69 WKTKQSN---VEVPFFPARVLLQDFTGIPAMVDFAAMREAVKTLGGDPEKVHPACPTDLT 125
Query: 128 IDHSVQVDFAR 138
+DHS+Q+DF++
Sbjct: 126 VDHSLQIDFSK 136
>BC117483-1|AAI17484.1| 963|Homo sapiens iron-responsive element
binding protein 2 protein.
Length = 963
Score = 308 bits (756), Expect = 2e-83
Identities = 145/261 (55%), Positives = 187/261 (71%), Gaps = 1/261 (0%)
Query: 140 PDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPGSGIVHQVNLEYLARVVFTGP-L 198
P+ + KNQ++EF RN+ER QF KW ++ F N+ ++PPG+G+ HQ+NLEYL+RVVF L
Sbjct: 211 PETVLKNQEVEFGRNRERLQFFKWSSRVFKNVAVIPPGTGMAHQINLEYLSRVVFEEKDL 270
Query: 199 LHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQAISMLLPKVVGYKLVGELNPLA 258
L PDSVVGTDSH TM+N IE EAVMLG +S+ LP+VVG +L G NP
Sbjct: 271 LFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVSLTLPEVVGCELTGSSNPFV 330
Query: 259 TSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRATVANMCPEFGATLAHFPVDAR 318
TS D+VL ITKHLR +GV GKFVEFFG GV LSI DR T+ANMCPE+GA L+ FPVD
Sbjct: 331 TSIDVVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPVDNV 390
Query: 319 SLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPVFSEVVELDLGDVVTSVSGPKR 378
+L++L T K K++ +E+YL+A K FR+ N +P +S+V++++L +V SVSGPKR
Sbjct: 391 TLKHLEHTGFSKAKLESMETYLKAVKLFRNDQNSSGEPEYSQVIQINLNSIVPSVSGPKR 450
Query: 379 PQDRVSVAIMKKDFQDCLTNK 399
PQDRV+V MK DFQ CL K
Sbjct: 451 PQDRVAVTDMKSDFQACLNEK 471
Score = 169 bits (410), Expect = 2e-41
Identities = 75/131 (57%), Positives = 105/131 (80%), Gaps = 4/131 (3%)
Query: 8 YQKLLKTIEINGSTYTYYDVSALGPKYDRLPFSIRVLLESCVRNCDNFQVLEKDVSNVLD 67
++ L++T+ + S ++DVS LG KYD LP+SIRVLLE+ VRNCD F + ++DV N+LD
Sbjct: 10 FEYLIETLN-DSSHKKFFDVSKLGTKYDVLPYSIRVLLEAAVRNCDGFLMKKEDVMNILD 68
Query: 68 WESKQGNEESVEIAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDRINPICPADLV 127
W++KQ N VE+ F PARV+LQD TG+PA+VDFAAMR+AVK LGGDP++++P CP DL
Sbjct: 69 WKTKQSN---VEVPFFPARVLLQDFTGIPAMVDFAAMREAVKTLGGDPEKVHPACPTDLT 125
Query: 128 IDHSVQVDFAR 138
+DHS+Q+DF++
Sbjct: 126 VDHSLQIDFSK 136
>BC117481-1|AAI17482.1| 963|Homo sapiens iron-responsive element
binding protein 2 protein.
Length = 963
Score = 308 bits (756), Expect = 2e-83
Identities = 145/261 (55%), Positives = 187/261 (71%), Gaps = 1/261 (0%)
Query: 140 PDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPGSGIVHQVNLEYLARVVFTGP-L 198
P+ + KNQ++EF RN+ER QF KW ++ F N+ ++PPG+G+ HQ+NLEYL+RVVF L
Sbjct: 211 PETVLKNQEVEFGRNRERLQFFKWSSRVFKNVAVIPPGTGMAHQINLEYLSRVVFEEKDL 270
Query: 199 LHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQAISMLLPKVVGYKLVGELNPLA 258
L PDSVVGTDSH TM+N IE EAVMLG +S+ LP+VVG +L G NP
Sbjct: 271 LFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVSLTLPEVVGCELTGSSNPFV 330
Query: 259 TSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRATVANMCPEFGATLAHFPVDAR 318
TS D+VL ITKHLR +GV GKFVEFFG GV LSI DR T+ANMCPE+GA L+ FPVD
Sbjct: 331 TSIDVVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPVDNV 390
Query: 319 SLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPVFSEVVELDLGDVVTSVSGPKR 378
+L++L T K K++ +E+YL+A K FR+ N +P +S+V++++L +V SVSGPKR
Sbjct: 391 TLKHLEHTGFSKAKLESMETYLKAVKLFRNDQNSSGEPEYSQVIQINLNSIVPSVSGPKR 450
Query: 379 PQDRVSVAIMKKDFQDCLTNK 399
PQDRV+V MK DFQ CL K
Sbjct: 451 PQDRVAVTDMKSDFQACLNEK 471
Score = 169 bits (410), Expect = 2e-41
Identities = 75/131 (57%), Positives = 105/131 (80%), Gaps = 4/131 (3%)
Query: 8 YQKLLKTIEINGSTYTYYDVSALGPKYDRLPFSIRVLLESCVRNCDNFQVLEKDVSNVLD 67
++ L++T+ + S ++DVS LG KYD LP+SIRVLLE+ VRNCD F + ++DV N+LD
Sbjct: 10 FEYLIETLN-DSSHKKFFDVSKLGTKYDVLPYSIRVLLEAAVRNCDGFLMKKEDVMNILD 68
Query: 68 WESKQGNEESVEIAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDRINPICPADLV 127
W++KQ N VE+ F PARV+LQD TG+PA+VDFAAMR+AVK LGGDP++++P CP DL
Sbjct: 69 WKTKQSN---VEVPFFPARVLLQDFTGIPAMVDFAAMREAVKTLGGDPEKVHPACPTDLT 125
Query: 128 IDHSVQVDFAR 138
+DHS+Q+DF++
Sbjct: 126 VDHSLQIDFSK 136
>AB209403-1|BAD92640.1| 802|Homo sapiens iron-responsive element
binding protein 2 variant protein.
Length = 802
Score = 308 bits (756), Expect = 2e-83
Identities = 145/261 (55%), Positives = 187/261 (71%), Gaps = 1/261 (0%)
Query: 140 PDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPGSGIVHQVNLEYLARVVFTGP-L 198
P+ + KNQ++EF RN+ER QF KW ++ F N+ ++PPG+G+ HQ+NLEYL+RVVF L
Sbjct: 243 PETVLKNQEVEFGRNRERLQFFKWSSRVFKNVAVIPPGTGMAHQINLEYLSRVVFEEKDL 302
Query: 199 LHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQAISMLLPKVVGYKLVGELNPLA 258
L PDSVVGTDSH TM+N IE EAVMLG +S+ LP+VVG +L G NP
Sbjct: 303 LFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVSLTLPEVVGCELTGSSNPFV 362
Query: 259 TSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRATVANMCPEFGATLAHFPVDAR 318
TS D+VL ITKHLR +GV GKFVEFFG GV LSI DR T+ANMCPE+GA L+ FPVD
Sbjct: 363 TSIDVVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPVDNV 422
Query: 319 SLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPVFSEVVELDLGDVVTSVSGPKR 378
+L++L T K K++ +E+YL+A K FR+ N +P +S+V++++L +V SVSGPKR
Sbjct: 423 TLKHLEHTGFSKAKLESMETYLKAVKLFRNDQNSSGEPEYSQVIQINLNSIVPSVSGPKR 482
Query: 379 PQDRVSVAIMKKDFQDCLTNK 399
PQDRV+V MK DFQ CL K
Sbjct: 483 PQDRVAVTDMKSDFQACLNEK 503
Score = 169 bits (410), Expect = 2e-41
Identities = 75/131 (57%), Positives = 105/131 (80%), Gaps = 4/131 (3%)
Query: 8 YQKLLKTIEINGSTYTYYDVSALGPKYDRLPFSIRVLLESCVRNCDNFQVLEKDVSNVLD 67
++ L++T+ + S ++DVS LG KYD LP+SIRVLLE+ VRNCD F + ++DV N+LD
Sbjct: 42 FEYLIETLN-DSSHKKFFDVSKLGTKYDVLPYSIRVLLEAAVRNCDGFLMKKEDVMNILD 100
Query: 68 WESKQGNEESVEIAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDRINPICPADLV 127
W++KQ N VE+ F PARV+LQD TG+PA+VDFAAMR+AVK LGGDP++++P CP DL
Sbjct: 101 WKTKQSN---VEVPFFPARVLLQDFTGIPAMVDFAAMREAVKTLGGDPEKVHPACPTDLT 157
Query: 128 IDHSVQVDFAR 138
+DHS+Q+DF++
Sbjct: 158 VDHSLQIDFSK 168
>M58511-1|AAA69901.1| 963|Homo sapiens iron-responsive
element-binding protein/iron regulatory protein 2
protein.
Length = 963
Score = 305 bits (750), Expect = 1e-82
Identities = 144/261 (55%), Positives = 186/261 (71%), Gaps = 1/261 (0%)
Query: 140 PDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPGSGIVHQVNLEYLARVVFTGP-L 198
P+ + KNQ++EF RN+ER QF KW ++ N+ ++PPG+G+ HQ+NLEYL+RVVF L
Sbjct: 211 PETVLKNQEVEFGRNRERLQFFKWSSRVLKNVAVIPPGTGMAHQINLEYLSRVVFEEKDL 270
Query: 199 LHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQAISMLLPKVVGYKLVGELNPLA 258
L PDSVVGTDSH TM+N IE EAVMLG +S+ LP+VVG +L G NP
Sbjct: 271 LFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVSLTLPEVVGCELTGSSNPFV 330
Query: 259 TSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRATVANMCPEFGATLAHFPVDAR 318
TS D+VL ITKHLR +GV GKFVEFFG GV LSI DR T+ANMCPE+GA L+ FPVD
Sbjct: 331 TSIDVVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPVDNV 390
Query: 319 SLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPVFSEVVELDLGDVVTSVSGPKR 378
+L++L T K K++ +E+YL+A K FR+ N +P +S+V++++L +V SVSGPKR
Sbjct: 391 TLKHLEHTGFSKAKLESMETYLKAVKLFRNDQNSSGEPEYSQVIQINLNSIVPSVSGPKR 450
Query: 379 PQDRVSVAIMKKDFQDCLTNK 399
PQDRV+V MK DFQ CL K
Sbjct: 451 PQDRVAVTDMKSDFQACLNEK 471
Score = 169 bits (410), Expect = 2e-41
Identities = 75/131 (57%), Positives = 105/131 (80%), Gaps = 4/131 (3%)
Query: 8 YQKLLKTIEINGSTYTYYDVSALGPKYDRLPFSIRVLLESCVRNCDNFQVLEKDVSNVLD 67
++ L++T+ + S ++DVS LG KYD LP+SIRVLLE+ VRNCD F + ++DV N+LD
Sbjct: 10 FEYLIETLN-DSSHKKFFDVSKLGTKYDVLPYSIRVLLEAAVRNCDGFLMKKEDVMNILD 68
Query: 68 WESKQGNEESVEIAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDRINPICPADLV 127
W++KQ N VE+ F PARV+LQD TG+PA+VDFAAMR+AVK LGGDP++++P CP DL
Sbjct: 69 WKTKQSN---VEVPFFPARVLLQDFTGIPAMVDFAAMREAVKTLGGDPEKVHPACPTDLT 125
Query: 128 IDHSVQVDFAR 138
+DHS+Q+DF++
Sbjct: 126 VDHSLQIDFSK 136
>U20180-1|AAA79926.1| 952|Homo sapiens iron-regulatory protein 2
protein.
Length = 952
Score = 304 bits (746), Expect = 4e-82
Identities = 143/261 (54%), Positives = 186/261 (71%), Gaps = 1/261 (0%)
Query: 140 PDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPGSGIVHQVNLEYLARVVFTGP-L 198
P+ + KNQ++EF RN+ER QF KW ++ N+ ++PPG+G+ HQ+NLEYL+RVVF L
Sbjct: 200 PETVLKNQEVEFGRNRERLQFFKWSSRVLKNVAVIPPGTGMAHQINLEYLSRVVFEEKDL 259
Query: 199 LHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQAISMLLPKVVGYKLVGELNPLA 258
L PDSVVGTDSH TM+N IE EAVMLG +S+ LP+VVG +L G NP
Sbjct: 260 LFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVSLTLPEVVGCELTGSSNPFV 319
Query: 259 TSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRATVANMCPEFGATLAHFPVDAR 318
TS D+VL ITKHLR +GV GKFVEFFG GV LSI DR T+ANMCPE+GA L+ FPVD
Sbjct: 320 TSIDVVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPVDNV 379
Query: 319 SLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPVFSEVVELDLGDVVTSVSGPKR 378
+L++L T K K++ +E+YL+A K FR+ N +P +S+V++++L +V SVSGPKR
Sbjct: 380 TLKHLEHTGFSKAKLESMETYLKAVKLFRNDQNSSGEPEYSQVIQINLNSIVPSVSGPKR 439
Query: 379 PQDRVSVAIMKKDFQDCLTNK 399
P+DRV+V MK DFQ CL K
Sbjct: 440 PRDRVAVTDMKSDFQACLNEK 460
Score = 167 bits (407), Expect = 5e-41
Identities = 75/128 (58%), Positives = 103/128 (80%), Gaps = 4/128 (3%)
Query: 11 LLKTIEINGSTYTYYDVSALGPKYDRLPFSIRVLLESCVRNCDNFQVLEKDVSNVLDWES 70
L++T+ + S ++DVS LG KYD LP+SIRVLLE+ VRNCD F + ++DV N+LDW++
Sbjct: 2 LIETLN-DSSHKKFFDVSKLGTKYDVLPYSIRVLLEAAVRNCDGFLMKKEDVMNILDWKT 60
Query: 71 KQGNEESVEIAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDRINPICPADLVIDH 130
KQ N VE+ F PARV+LQD TG+PA+VDFAAMR+AVK LGGDP++++P CP DL +DH
Sbjct: 61 KQSN---VEVPFFPARVLLQDFTGIPAMVDFAAMREAVKTLGGDPEKVHPACPTDLTVDH 117
Query: 131 SVQVDFAR 138
S+Q+DF++
Sbjct: 118 SLQIDFSK 125
>BC017880-1|AAH17880.1| 343|Homo sapiens IREB2 protein protein.
Length = 343
Score = 169 bits (410), Expect = 2e-41
Identities = 75/131 (57%), Positives = 105/131 (80%), Gaps = 4/131 (3%)
Query: 8 YQKLLKTIEINGSTYTYYDVSALGPKYDRLPFSIRVLLESCVRNCDNFQVLEKDVSNVLD 67
++ L++T+ + S ++DVS LG KYD LP+SIRVLLE+ VRNCD F + ++DV N+LD
Sbjct: 10 FEYLIETLN-DSSHKKFFDVSKLGTKYDVLPYSIRVLLEAAVRNCDGFLMKKEDVMNILD 68
Query: 68 WESKQGNEESVEIAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDRINPICPADLV 127
W++KQ N VE+ F PARV+LQD TG+PA+VDFAAMR+AVK LGGDP++++P CP DL
Sbjct: 69 WKTKQSN---VEVPFFPARVLLQDFTGIPAMVDFAAMREAVKTLGGDPEKVHPACPTDLT 125
Query: 128 IDHSVQVDFAR 138
+DHS+Q+DF++
Sbjct: 126 VDHSLQIDFSK 136
Score = 152 bits (368), Expect = 3e-36
Identities = 72/131 (54%), Positives = 92/131 (70%), Gaps = 1/131 (0%)
Query: 140 PDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPGSGIVHQVNLEYLARVVF-TGPL 198
P+ + KNQ++EF RN+ER QF KW ++ F N+ ++PPG+G+ HQ+NLEYL+RVVF L
Sbjct: 211 PETVLKNQEVEFGRNRERLQFFKWSSRVFKNVAVIPPGTGMAHQINLEYLSRVVFEEKDL 270
Query: 199 LHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQAISMLLPKVVGYKLVGELNPLA 258
L PDSVVGTDSH TM+N IE EAVMLG +S+ LP+VVG +L G NP
Sbjct: 271 LFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVSLTLPEVVGCELTGSSNPFV 330
Query: 259 TSTDLVLTITK 269
TS D+VL ITK
Sbjct: 331 TSIDVVLGITK 341
>CR536568-1|CAG38805.1| 780|Homo sapiens ACO2 protein.
Length = 780
Score = 113 bits (272), Expect = 1e-24
Identities = 92/322 (28%), Positives = 148/322 (45%), Gaps = 34/322 (10%)
Query: 59 EKDVSNVLDWESKQGNEESVE-IAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDR 117
EK V LD + Q E + +P RV +QD T A++ F + +
Sbjct: 67 EKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQF---------ISSGLSK 117
Query: 118 INPICPADLVIDHSVQVDFARTPDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPG 177
+ P+ + DH ++ D L + +D+ N+E + FL + + PG
Sbjct: 118 V--AVPSTIHCDHLIEAQVGGEKD-LRRAKDI----NQEVYNFLATAGAKY-GVGFWKPG 169
Query: 178 SGIVHQVNLEYLARVVFTGPLLHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQA 237
SGI+HQ+ LE A + G LL +GTDSHT + +A VM G
Sbjct: 170 SGIIHQIILENYA---YPGVLL-----IGTDSHTPNGDGLGGICIGVGGADAVDVMAGIP 221
Query: 238 ISMLLPKVVGYKLVGELNPLATSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRA 297
+ PKV+G KL G L+ ++ D++L + L G G VE+ GPGV ++S A
Sbjct: 222 WELKCPKVIGVKLTGSLSGWSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMA 281
Query: 298 TVANMCPEFGATLAHFPVDARSLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPV 357
T+ NM E GAT + FP + R +YL +T R E +F+D+ P+
Sbjct: 282 TICNMGAEIGATTSVFPYNHRMKKYLSKTGR--------EDIANLADEFKDHLVPDPGCH 333
Query: 358 FSEVVELDLGDVVTSVSGPKRP 379
+ +++E++L ++ ++GP P
Sbjct: 334 YDQLIEINLSELKPHINGPFTP 355
>U87939-1|AAC39921.1| 780|Homo sapiens aconitate hydratase protein.
Length = 780
Score = 113 bits (271), Expect = 1e-24
Identities = 92/322 (28%), Positives = 147/322 (45%), Gaps = 34/322 (10%)
Query: 59 EKDVSNVLDWESKQGNEESVE-IAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDR 117
EK V LD + Q E + +P RV +QD T A++ F + +
Sbjct: 67 EKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQF---------ISSGLSK 117
Query: 118 INPICPADLVIDHSVQVDFARTPDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPG 177
+ P+ + DH ++ D L + +D+ N+E + FL + + PG
Sbjct: 118 V--AVPSTIHCDHLIEAQVGGEKD-LRRAKDI----NQEVYNFLATAGAKY-GVGFWKPG 169
Query: 178 SGIVHQVNLEYLARVVFTGPLLHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQA 237
SGI+HQ+ LE A + G LL +GTDSHT +A VM G
Sbjct: 170 SGIIHQIILENYA---YPGVLL-----IGTDSHTPNGGGLGGICIGVGGADAVDVMAGIP 221
Query: 238 ISMLLPKVVGYKLVGELNPLATSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRA 297
+ PKV+G KL G L+ ++ D++L + L G G VE+ GPGV ++S A
Sbjct: 222 WELKCPKVIGVKLTGSLSGWSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMA 281
Query: 298 TVANMCPEFGATLAHFPVDARSLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPV 357
T+ NM E GAT + FP + R +YL +T R E +F+D+ P+
Sbjct: 282 TICNMGAEIGATTSVFPYNHRMKKYLSKTGR--------EDIANLADEFKDHLVPDPGCH 333
Query: 358 FSEVVELDLGDVVTSVSGPKRP 379
+ +++E++L ++ ++GP P
Sbjct: 334 YDQLIEINLSELKPHINGPFTP 355
>U80040-1|AAB38416.1| 780|Homo sapiens mitochondrial aconitase
protein.
Length = 780
Score = 113 bits (271), Expect = 1e-24
Identities = 92/322 (28%), Positives = 146/322 (45%), Gaps = 34/322 (10%)
Query: 59 EKDVSNVLDWESKQGNEESVE-IAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDR 117
EK V LD + Q E + +P RV +QD T A++ F + +
Sbjct: 67 EKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQF---------ISSGLSK 117
Query: 118 INPICPADLVIDHSVQVDFARTPDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPG 177
+ P+ + DH ++ D L + +D+ N+E + FL + + PG
Sbjct: 118 V--AVPSTIHCDHLIEAQVGDEKD-LRRAKDI----NQEVYNFLATAGDKY-GVGFWSPG 169
Query: 178 SGIVHQVNLEYLARVVFTGPLLHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQA 237
SGI+HQ+ LE A + G LL +GTDSHT +A VM G
Sbjct: 170 SGIIHQIILENYA---YPGVLL-----IGTDSHTPNGGGLGGICIGVGGADAVDVMAGIP 221
Query: 238 ISMLLPKVVGYKLVGELNPLATSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRA 297
+ PKV+G KL G L+ + D++L + L G G VE+ GPGV ++S A
Sbjct: 222 WELKCPKVIGVKLTGSLSGWTSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSMSCTGMA 281
Query: 298 TVANMCPEFGATLAHFPVDARSLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPV 357
T+ NM E GAT + FP + R +YL +T R E +F+D+ P+
Sbjct: 282 TICNMGAEIGATTSVFPYNHRMKKYLSKTGR--------EDIANLADEFKDHLVPDPGCH 333
Query: 358 FSEVVELDLGDVVTSVSGPKRP 379
+ +++E++L ++ ++GP P
Sbjct: 334 YDQLIEINLSELKPHINGPFTP 355
>CR456365-1|CAG30251.1| 780|Homo sapiens ACO2 protein.
Length = 780
Score = 113 bits (271), Expect = 1e-24
Identities = 92/322 (28%), Positives = 147/322 (45%), Gaps = 34/322 (10%)
Query: 59 EKDVSNVLDWESKQGNEESVE-IAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDR 117
EK V LD + Q E + +P RV +QD T A++ F + +
Sbjct: 67 EKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQF---------ISSGLSK 117
Query: 118 INPICPADLVIDHSVQVDFARTPDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPG 177
+ P+ + DH ++ D L + +D+ N+E + FL + + PG
Sbjct: 118 V--AVPSTIHCDHLIEAQVGGEKD-LRRAKDI----NQEVYNFLATAGAKY-GVGFWKPG 169
Query: 178 SGIVHQVNLEYLARVVFTGPLLHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQA 237
SGI+HQ+ LE A + G LL +GTDSHT +A VM G
Sbjct: 170 SGIIHQIILENYA---YPGVLL-----IGTDSHTPNGGGLGGICIGVGGADAVDVMAGIP 221
Query: 238 ISMLLPKVVGYKLVGELNPLATSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRA 297
+ PKV+G KL G L+ ++ D++L + L G G VE+ GPGV ++S A
Sbjct: 222 WELKCPKVIGVKLTGSLSGWSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMA 281
Query: 298 TVANMCPEFGATLAHFPVDARSLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPV 357
T+ NM E GAT + FP + R +YL +T R E +F+D+ P+
Sbjct: 282 TICNMGAEIGATTSVFPYNHRMKKYLSKTGR--------EDIANLADEFKDHLVPDPGCH 333
Query: 358 FSEVVELDLGDVVTSVSGPKRP 379
+ +++E++L ++ ++GP P
Sbjct: 334 YDQLIEINLSELKPHINGPFTP 355
>BC014092-1|AAH14092.1| 780|Homo sapiens aconitase 2, mitochondrial
protein.
Length = 780
Score = 113 bits (271), Expect = 1e-24
Identities = 92/322 (28%), Positives = 147/322 (45%), Gaps = 34/322 (10%)
Query: 59 EKDVSNVLDWESKQGNEESVE-IAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDR 117
EK V LD + Q E + +P RV +QD T A++ F + +
Sbjct: 67 EKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQF---------ISSGLSK 117
Query: 118 INPICPADLVIDHSVQVDFARTPDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPG 177
+ P+ + DH ++ D L + +D+ N+E + FL + + PG
Sbjct: 118 V--AVPSTIHCDHLIEAQVGGEKD-LRRAKDI----NQEVYNFLATAGAKY-GVGFWKPG 169
Query: 178 SGIVHQVNLEYLARVVFTGPLLHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQA 237
SGI+HQ+ LE A + G LL +GTDSHT +A VM G
Sbjct: 170 SGIIHQIILENYA---YPGVLL-----IGTDSHTPNGGGLGGICIGVGGADAVDVMAGIP 221
Query: 238 ISMLLPKVVGYKLVGELNPLATSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRA 297
+ PKV+G KL G L+ ++ D++L + L G G VE+ GPGV ++S A
Sbjct: 222 WELKCPKVIGVKLTGSLSGWSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMA 281
Query: 298 TVANMCPEFGATLAHFPVDARSLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPV 357
T+ NM E GAT + FP + R +YL +T R E +F+D+ P+
Sbjct: 282 TICNMGAEIGATTSVFPYNHRMKKYLSKTGR--------EDIANLADEFKDHLVPDPGCH 333
Query: 358 FSEVVELDLGDVVTSVSGPKRP 379
+ +++E++L ++ ++GP P
Sbjct: 334 YDQLIEINLSELKPHINGPFTP 355
>AL023553-3|CAI20278.1| 780|Homo sapiens aconitase 2, mitochondrial
protein.
Length = 780
Score = 113 bits (271), Expect = 1e-24
Identities = 92/322 (28%), Positives = 147/322 (45%), Gaps = 34/322 (10%)
Query: 59 EKDVSNVLDWESKQGNEESVE-IAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDR 117
EK V LD + Q E + +P RV +QD T A++ F + +
Sbjct: 67 EKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQF---------ISSGLSK 117
Query: 118 INPICPADLVIDHSVQVDFARTPDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPG 177
+ P+ + DH ++ D L + +D+ N+E + FL + + PG
Sbjct: 118 V--AVPSTIHCDHLIEAQVGGEKD-LRRAKDI----NQEVYNFLATAGAKY-GVGFWKPG 169
Query: 178 SGIVHQVNLEYLARVVFTGPLLHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQA 237
SGI+HQ+ LE A + G LL +GTDSHT +A VM G
Sbjct: 170 SGIIHQIILENYA---YPGVLL-----IGTDSHTPNGGGLGGICIGVGGADAVDVMAGIP 221
Query: 238 ISMLLPKVVGYKLVGELNPLATSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRA 297
+ PKV+G KL G L+ ++ D++L + L G G VE+ GPGV ++S A
Sbjct: 222 WELKCPKVIGVKLTGSLSGWSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMA 281
Query: 298 TVANMCPEFGATLAHFPVDARSLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPV 357
T+ NM E GAT + FP + R +YL +T R E +F+D+ P+
Sbjct: 282 TICNMGAEIGATTSVFPYNHRMKKYLSKTGR--------EDIANLADEFKDHLVPDPGCH 333
Query: 358 FSEVVELDLGDVVTSVSGPKRP 379
+ +++E++L ++ ++GP P
Sbjct: 334 YDQLIEINLSELKPHINGPFTP 355
>AL008582-3|CAI17931.1| 780|Homo sapiens aconitase 2, mitochondrial
protein.
Length = 780
Score = 113 bits (271), Expect = 1e-24
Identities = 92/322 (28%), Positives = 147/322 (45%), Gaps = 34/322 (10%)
Query: 59 EKDVSNVLDWESKQGNEESVE-IAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDR 117
EK V LD + Q E + +P RV +QD T A++ F + +
Sbjct: 67 EKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQF---------ISSGLSK 117
Query: 118 INPICPADLVIDHSVQVDFARTPDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPG 177
+ P+ + DH ++ D L + +D+ N+E + FL + + PG
Sbjct: 118 V--AVPSTIHCDHLIEAQVGGEKD-LRRAKDI----NQEVYNFLATAGAKY-GVGFWKPG 169
Query: 178 SGIVHQVNLEYLARVVFTGPLLHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQA 237
SGI+HQ+ LE A + G LL +GTDSHT +A VM G
Sbjct: 170 SGIIHQIILENYA---YPGVLL-----IGTDSHTPNGGGLGGICIGVGGADAVDVMAGIP 221
Query: 238 ISMLLPKVVGYKLVGELNPLATSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRA 297
+ PKV+G KL G L+ ++ D++L + L G G VE+ GPGV ++S A
Sbjct: 222 WELKCPKVIGVKLTGSLSGWSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMA 281
Query: 298 TVANMCPEFGATLAHFPVDARSLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPV 357
T+ NM E GAT + FP + R +YL +T R E +F+D+ P+
Sbjct: 282 TICNMGAEIGATTSVFPYNHRMKKYLSKTGR--------EDIANLADEFKDHLVPDPGCH 333
Query: 358 FSEVVELDLGDVVTSVSGPKRP 379
+ +++E++L ++ ++GP P
Sbjct: 334 YDQLIEINLSELKPHINGPFTP 355
>AF093096-1|AAD19351.2| 780|Homo sapiens aconitase protein.
Length = 780
Score = 113 bits (271), Expect = 1e-24
Identities = 92/322 (28%), Positives = 146/322 (45%), Gaps = 34/322 (10%)
Query: 59 EKDVSNVLDWESKQGNEESVE-IAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDR 117
EK V LD + Q E + +P RV +QD T A++ F + +
Sbjct: 67 EKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQF---------ISSGLSK 117
Query: 118 INPICPADLVIDHSVQVDFARTPDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPG 177
+ P+ + DH ++ D L + +D+ N+E + FL + + PG
Sbjct: 118 V--AVPSTIHCDHLIEAQVGDEKD-LRRAKDI----NQEVYNFLATAGDKY-GVGFWSPG 169
Query: 178 SGIVHQVNLEYLARVVFTGPLLHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQA 237
SGI+HQ+ LE A + G LL +GTDSHT +A VM G
Sbjct: 170 SGIIHQIILENYA---YPGVLL-----IGTDSHTPNGGGLGGICIGVGGADAVDVMAGIP 221
Query: 238 ISMLLPKVVGYKLVGELNPLATSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRA 297
+ PKV+G KL G L+ + D++L + L G G VE+ GPGV ++S A
Sbjct: 222 WELKCPKVIGVKLTGSLSGWTSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSMSCTGMA 281
Query: 298 TVANMCPEFGATLAHFPVDARSLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPV 357
T+ NM E GAT + FP + R +YL +T R E +F+D+ P+
Sbjct: 282 TICNMGAEIGATTSVFPYNHRMKKYLSKTGR--------EDIANLADEFKDHLVPDPGCH 333
Query: 358 FSEVVELDLGDVVTSVSGPKRP 379
+ +++E++L ++ ++GP P
Sbjct: 334 YDQLIEINLSELKPHINGPFTP 355
>BC026196-1|AAH26196.1| 780|Homo sapiens aconitase 2, mitochondrial
protein.
Length = 780
Score = 109 bits (262), Expect = 2e-23
Identities = 91/322 (28%), Positives = 146/322 (45%), Gaps = 34/322 (10%)
Query: 59 EKDVSNVLDWESKQGNEESVE-IAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDR 117
EK V LD + Q E + +P RV +QD T A++ F + +
Sbjct: 67 EKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQF---------ISSGLSK 117
Query: 118 INPICPADLVIDHSVQVDFARTPDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPG 177
+ P+ + DH ++ D L + +D+ N+E + FL + + PG
Sbjct: 118 V--AVPSTIHCDHLIEAQVGGEKD-LRRAKDI----NQEVYNFLATAGAKY-GVGFWKPG 169
Query: 178 SGIVHQVNLEYLARVVFTGPLLHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQA 237
SGI+HQ+ LE A + G LL +GTDSHT +A VM G
Sbjct: 170 SGIIHQIILENYA---YPGVLL-----IGTDSHTPNGGGLGGICIRVGGADAVDVMAGIP 221
Query: 238 ISMLLPKVVGYKLVGELNPLATSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALSIADRA 297
+ PKV+G KL G L+ ++ D++L + L G G VE+ G GV ++S A
Sbjct: 222 WELKCPKVIGVKLTGSLSGWSSPKDVILKVAGILTVKGGTGAIVEYHGHGVDSISCTGMA 281
Query: 298 TVANMCPEFGATLAHFPVDARSLEYLHQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPV 357
T+ NM E GAT + FP + R +YL +T R E +F+D+ P+
Sbjct: 282 TICNMGAEIGATTSVFPYNHRMKKYLSKTGR--------EDIANLADEFKDHLVPDPGCH 333
Query: 358 FSEVVELDLGDVVTSVSGPKRP 379
+ +++E++L ++ ++GP P
Sbjct: 334 YDQLIEINLSELKPHINGPFTP 355
>AL023553-4|CAM28239.1| 805|Homo sapiens aconitase 2, mitochondrial
protein.
Length = 805
Score = 90.2 bits (214), Expect = 1e-17
Identities = 93/347 (26%), Positives = 149/347 (42%), Gaps = 59/347 (17%)
Query: 59 EKDVSNVLDWESKQGNEESVE-IAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDR 117
EK V LD + Q E + +P RV +QD T A++ F + +
Sbjct: 67 EKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQF---------ISSGLSK 117
Query: 118 INPICPADLVIDHSVQVDFARTPDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPG 177
+ P+ + DH ++ D L + +D+ N+E + FL + + PG
Sbjct: 118 V--AVPSTIHCDHLIEAQVGGEKD-LRRAKDI----NQEVYNFLATAGAKY-GVGFWKPG 169
Query: 178 SGIVHQVNLEYLARVVFTGPLLHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQA 237
SGI+HQ+ LE A + G LL +GTDSHT +A VM G
Sbjct: 170 SGIIHQIILENYA---YPGVLL-----IGTDSHTPNGGGLGGICIGVGGADAVDVMAGIP 221
Query: 238 ISMLLPKVVGYKLVGELNPLATSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALS----- 292
+ PKV+G KL G L+ ++ D++L + L G G VE+ GPGV ++S
Sbjct: 222 WELKCPKVIGVKLTGSLSGWSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGEE 281
Query: 293 -----------------IADR---ATVANMCPEFGATLAHFPVDARSLEYLHQTNRPKEK 332
+ R AT+ NM E GAT + FP + R +YL +T R
Sbjct: 282 GGQATWPLPCAGPDGSPVGSRSGMATICNMGAEIGATTSVFPYNHRMKKYLSKTGR---- 337
Query: 333 IDVIESYLRATKQFRDYTNPEQDPVFSEVVELDLGDVVTSVSGPKRP 379
E +F+D+ P+ + +++E++L ++ ++GP P
Sbjct: 338 ----EDIANLADEFKDHLVPDPGCHYDQLIEINLSELKPHINGPFTP 380
>AL008582-4|CAM25244.1| 805|Homo sapiens aconitase 2, mitochondrial
protein.
Length = 805
Score = 90.2 bits (214), Expect = 1e-17
Identities = 93/347 (26%), Positives = 149/347 (42%), Gaps = 59/347 (17%)
Query: 59 EKDVSNVLDWESKQGNEESVE-IAFKPARVILQDLTGVPAVVDFAAMRDAVKDLGGDPDR 117
EK V LD + Q E + +P RV +QD T A++ F + +
Sbjct: 67 EKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQF---------ISSGLSK 117
Query: 118 INPICPADLVIDHSVQVDFARTPDALNKNQDLEFVRNKERFQFLKWGAQAFDNMLIVPPG 177
+ P+ + DH ++ D L + +D+ N+E + FL + + PG
Sbjct: 118 V--AVPSTIHCDHLIEAQVGGEKD-LRRAKDI----NQEVYNFLATAGAKY-GVGFWKPG 169
Query: 178 SGIVHQVNLEYLARVVFTGPLLHPDSVVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQA 237
SGI+HQ+ LE A + G LL +GTDSHT +A VM G
Sbjct: 170 SGIIHQIILENYA---YPGVLL-----IGTDSHTPNGGGLGGICIGVGGADAVDVMAGIP 221
Query: 238 ISMLLPKVVGYKLVGELNPLATSTDLVLTITKHLRSLGVVGKFVEFFGPGVGALS----- 292
+ PKV+G KL G L+ ++ D++L + L G G VE+ GPGV ++S
Sbjct: 222 WELKCPKVIGVKLTGSLSGWSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGEE 281
Query: 293 -----------------IADR---ATVANMCPEFGATLAHFPVDARSLEYLHQTNRPKEK 332
+ R AT+ NM E GAT + FP + R +YL +T R
Sbjct: 282 GGQATWPLPCAGPDGSPVGSRSGMATICNMGAEIGATTSVFPYNHRMKKYLSKTGR---- 337
Query: 333 IDVIESYLRATKQFRDYTNPEQDPVFSEVVELDLGDVVTSVSGPKRP 379
E +F+D+ P+ + +++E++L ++ ++GP P
Sbjct: 338 ----EDIANLADEFKDHLVPDPGCHYDQLIEINLSELKPHINGPFTP 380
>BX538349-1|CAD98144.1| 84|Homo sapiens hypothetical protein
protein.
Length = 84
Score = 89.4 bits (212), Expect = 2e-17
Identities = 41/72 (56%), Positives = 53/72 (73%)
Query: 328 RPKEKIDVIESYLRATKQFRDYTNPEQDPVFSEVVELDLGDVVTSVSGPKRPQDRVSVAI 387
R +EK+ I+ YL+A FRD+ +P QDP F++VVELDL VV SGPKRPQD+V+V+
Sbjct: 2 RDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVVELDLKTVVPCCSGPKRPQDKVAVSD 61
Query: 388 MKKDFQDCLTNK 399
MKKDF+ CL K
Sbjct: 62 MKKDFESCLGAK 73
>AF086790-1|AAC35557.1| 600|Homo sapiens aconitase precursor
protein.
Length = 600
Score = 87.4 bits (207), Expect = 8e-17
Identities = 54/176 (30%), Positives = 88/176 (50%), Gaps = 8/176 (4%)
Query: 204 VVGTDSHTTMINXXXXXXXXXXXIEAEAVMLGQAISMLLPKVVGYKLVGELNPLATSTDL 263
++GTDSHT + VM G + KV+ KL G L+ + D+
Sbjct: 9 LIGTDSHTPNGGGLGGISIGVGGRDRVDVMAGIPCELKCTKVIAMKLTGSLSGWTSPKDV 68
Query: 264 VLTITKHLRSLGVVGKFVEFFGPGVGALSIADRATVANMCPEFGATLAHFPVDARSLEYL 323
+L + L G G VE+ GPGV ++S AT+ NM E GAT + FP + R +YL
Sbjct: 69 ILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMKKYL 128
Query: 324 HQTNRPKEKIDVIESYLRATKQFRDYTNPEQDPVFSEVVELDLGDVVTSVSGPKRP 379
+T R D+ + LR ++F+D+ P+ + +V+E++L ++ ++GP P
Sbjct: 129 SKTGR----ADI--ASLR--EEFKDHLVPDPGCQYDQVIEINLNELKPHINGPFTP 176
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.137 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 58,871,681
Number of Sequences: 224733
Number of extensions: 2301624
Number of successful extensions: 3611
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 3523
Number of HSP's gapped (non-prelim): 37
length of query: 419
length of database: 73,234,838
effective HSP length: 92
effective length of query: 327
effective length of database: 52,559,402
effective search space: 17186924454
effective search space used: 17186924454
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 67 (31.1 bits)
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