Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001713-TA|BGIBMGA001713-PA|IPR001611|Leucine-rich
repeat, IPR003591|Leucine-rich repeat, typical subtype
(395 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein. 115 3e-25
BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat con... 115 3e-25
AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein. 114 6e-25
M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth facto... 113 8e-25
BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth fac... 113 8e-25
AL031724-2|CAC36078.1| 605|Homo sapiens C447E6.2 (insulin-like ... 113 8e-25
AF192554-1|AAF06774.1| 605|Homo sapiens acid-labile subunit pro... 113 8e-25
BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N, pol... 105 2e-22
J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precur... 105 3e-22
BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N, pol... 105 3e-22
Z23091-1|CAA80637.1| 560|Homo sapiens platelet glycoprotein V p... 102 2e-21
L11238-1|AAA03069.1| 560|Homo sapiens platelet membrane glycopr... 102 2e-21
BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein. 100 2e-20
BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein. 100 2e-20
BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein. 99 2e-20
AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich repeat-con... 99 2e-20
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 97 7e-20
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 97 7e-20
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 97 7e-20
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 97 7e-20
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 97 7e-20
AF346711-1|AAK31153.1| 951|Homo sapiens G-protein couple recept... 97 1e-19
AL159161-1|CAI17102.1| 754|Homo sapiens relaxin/insulin-like fa... 96 2e-19
AL138708-1|CAH73785.1| 754|Homo sapiens relaxin/insulin-like fa... 96 2e-19
AF453828-1|AAL73946.1| 754|Homo sapiens G protein-coupled recep... 96 2e-19
AF403384-1|AAL69324.2| 754|Homo sapiens LGR8 protein. 96 2e-19
BC040188-1|AAH40188.1| 692|Homo sapiens LOC150356 protein protein. 95 3e-19
BC068590-1|AAH68590.1| 778|Homo sapiens LOC150356 protein protein. 95 4e-19
AL035681-1|CAI22653.1| 762|Homo sapiens protein ( Human DNA seq... 95 4e-19
AF257182-1|AAF68989.1| 951|Homo sapiens G-protein-coupled recep... 93 1e-18
BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein. 93 2e-18
AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein. 93 2e-18
AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein. 93 2e-18
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 92 4e-18
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 92 4e-18
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 92 4e-18
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 92 4e-18
AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein L... 90 1e-17
AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein L... 90 1e-17
BC036337-1|AAH36337.1| 811|Homo sapiens KIAA0644 gene product p... 89 2e-17
AB014544-1|BAA31619.2| 887|Homo sapiens KIAA0644 protein protein. 89 2e-17
BC113617-1|AAI13618.1| 757|Homo sapiens relaxin/insulin-like fa... 88 4e-17
BC112142-1|AAI12143.1| 757|Homo sapiens leucine-rich repeat-con... 88 4e-17
AY899850-1|AAX85198.1| 724|Homo sapiens LGR7.10 protein. 88 4e-17
AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich repeat-con... 88 4e-17
AF190500-1|AAG17167.1| 757|Homo sapiens leucine-rich repeat-con... 88 4e-17
AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein. 88 4e-17
BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich repeat-con... 87 1e-16
BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich repeat-con... 87 1e-16
BC034389-1|AAH34389.1| 347|Homo sapiens leucine-rich alpha-2-gl... 87 1e-16
BC013767-1|AAH13767.1| 601|Homo sapiens VASN protein protein. 87 1e-16
AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-couple... 87 1e-16
AB073607-1|BAD38644.1| 347|Homo sapiens leucine-rich alpha-2-gl... 87 1e-16
AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein. 86 2e-16
AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein. 86 2e-16
AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens ... 86 2e-16
BC070198-1|AAH70198.1| 347|Homo sapiens leucine-rich alpha-2-gl... 86 2e-16
AF403428-1|AAK95527.1| 347|Homo sapiens leucine-rich alpha-2-gl... 86 2e-16
BC131897-1|AAI31898.1| 420|Homo sapiens LRRC4B protein protein. 85 3e-16
BC032460-1|AAH32460.1| 634|Homo sapiens Unknown (protein for IM... 85 3e-16
AC108017-1|AAY41039.1| 260|Homo sapiens unknown protein. 85 3e-16
AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled recep... 85 5e-16
BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich repeat-con... 84 7e-16
AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor p... 84 7e-16
AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich repeat-con... 84 7e-16
BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein. 84 9e-16
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 84 9e-16
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 84 9e-16
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 84 9e-16
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 81 7e-15
BC110058-1|AAI10059.1| 518|Homo sapiens leucine rich repeat tra... 81 9e-15
BC099738-1|AAH99738.1| 518|Homo sapiens leucine rich repeat tra... 81 9e-15
BC098301-1|AAH98301.1| 519|Homo sapiens LRRTM4 protein protein. 81 9e-15
BC098267-1|AAH98267.1| 519|Homo sapiens LRRTM4 protein protein. 81 9e-15
AY358324-1|AAQ88690.1| 590|Homo sapiens GFHL3075 protein. 81 9e-15
AY182030-1|AAO67551.1| 518|Homo sapiens leucine-rich repeat tra... 81 9e-15
AK126961-1|BAC86764.1| 518|Homo sapiens protein ( Homo sapiens ... 81 9e-15
AY358312-1|AAQ88679.1| 716|Homo sapiens NLRR protein. 80 2e-14
AB074161-1|BAE45733.1| 716|Homo sapiens neuronal leucine-rich r... 80 2e-14
AB040930-1|BAA96021.1| 730|Homo sapiens KIAA1497 protein protein. 80 2e-14
BC111067-1|AAI11068.1| 513|Homo sapiens leucine rich repeat con... 79 2e-14
AB178281-1|BAD97811.1| 513|Homo sapiens LRRC24 protein protein. 79 2e-14
BC113717-1|AAI13718.1| 581|Homo sapiens leucine rich repeat tra... 79 3e-14
BC113715-1|AAI13716.1| 581|Homo sapiens leucine rich repeat tra... 79 3e-14
BC111492-1|AAI11493.1| 581|Homo sapiens leucine rich repeat tra... 79 3e-14
AY358315-1|AAQ88681.1| 513|Homo sapiens GFNV803 protein. 79 3e-14
AY358114-1|AAQ88481.1| 606|Homo sapiens Tango hlg protein. 79 3e-14
AY182028-1|AAO67549.1| 513|Homo sapiens leucine-rich repeat tra... 79 3e-14
AL353746-1|CAC22713.1| 606|Homo sapiens leucine rich repeat neu... 79 3e-14
AK056372-1|BAB71167.1| 606|Homo sapiens protein ( Homo sapiens ... 79 3e-14
BC011057-1|AAH11057.2| 620|Homo sapiens leucine rich repeat and... 78 5e-14
AY324320-1|AAQ97216.1| 620|Homo sapiens leucine-rich repeat neu... 78 5e-14
AY250221-1|AAP82838.1| 420|Homo sapiens nogo receptor-like 3 pr... 78 5e-14
AL834260-1|CAD38935.1| 577|Homo sapiens hypothetical protein pr... 78 5e-14
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 78 5e-14
U96769-1|AAC13410.1| 359|Homo sapiens chondroadherin protein. 78 6e-14
BC117276-1|AAI17277.1| 420|Homo sapiens reticulon 4 receptor-li... 78 6e-14
BC113673-1|AAI13674.1| 420|Homo sapiens reticulon 4 receptor-li... 78 6e-14
BC073974-1|AAH73974.1| 359|Homo sapiens chondroadherin protein. 78 6e-14
BC036360-1|AAH36360.1| 359|Homo sapiens chondroadherin protein. 78 6e-14
BC034947-1|AAH34947.1| 716|Homo sapiens leucine rich repeat neu... 78 6e-14
AY029183-1|AAK31796.1| 798|Homo sapiens SLIT1 isoform B protein. 78 6e-14
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 78 6e-14
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 78 6e-14
AL512424-3|CAI14257.1| 409|Homo sapiens slit homolog 1 (Drosoph... 78 6e-14
AL512424-1|CAI14255.1| 782|Homo sapiens slit homolog 1 (Drosoph... 78 6e-14
AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 78 6e-14
AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 78 6e-14
AF532858-1|AAP21835.1| 420|Homo sapiens Nogo-66 receptor homolo... 78 6e-14
AF371328-1|AAK51556.1| 359|Homo sapiens chondroadherin protein. 78 6e-14
AB208943-1|BAD92180.1| 627|Homo sapiens leucine-rich repeat-con... 78 6e-14
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 77 8e-14
BC126410-1|AAI26411.1| 516|Homo sapiens leucine rich repeat tra... 77 1e-13
BC126408-1|AAI26409.1| 516|Homo sapiens leucine rich repeat tra... 77 1e-13
BC068558-1|AAH68558.1| 614|Homo sapiens LINGO1 protein protein. 77 1e-13
AY358284-1|AAQ88651.1| 620|Homo sapiens QVSK201 protein. 77 1e-13
AY182026-1|AAO67547.1| 516|Homo sapiens leucine-rich repeat tra... 77 1e-13
AB007876-1|BAA24846.2| 529|Homo sapiens KIAA0416 protein. 77 1e-13
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 77 1e-13
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 77 1e-13
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 77 1e-13
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 77 1e-13
CR456360-1|CAG30246.1| 473|Homo sapiens Em:AC007663.1 protein. 76 2e-13
BC011787-1|AAH11787.1| 473|Homo sapiens reticulon 4 receptor pr... 76 2e-13
AY899851-1|AAX85199.1| 730|Homo sapiens LGR8.1 protein. 76 2e-13
AY358297-1|AAQ88664.1| 473|Homo sapiens NOGOR protein. 76 2e-13
AF283463-1|AAG53612.1| 473|Homo sapiens Nogo receptor protein. 76 2e-13
Z93015-1|CAI42364.1| 481|Homo sapiens nyctalopin protein. 76 3e-13
BC112242-1|AAI12243.1| 481|Homo sapiens nyctalopin protein. 76 3e-13
AJ278865-1|CAC19014.1| 481|Homo sapiens leucine-rich repeat pro... 76 3e-13
AF254868-1|AAG42685.1| 481|Homo sapiens nyctalopin protein. 76 3e-13
BC041374-1|AAH41374.3| 640|Homo sapiens LRRC4C protein protein. 75 6e-13
AY358293-1|AAQ88660.1| 640|Homo sapiens LNKM292 protein. 75 6e-13
AB046800-1|BAB13406.1| 640|Homo sapiens KIAA1580 protein protein. 75 6e-13
BC045113-1|AAH45113.1| 522|Homo sapiens LRRTM1 protein protein. 74 8e-13
AY899849-1|AAX85197.1| 709|Homo sapiens LGR7.2 protein. 74 8e-13
AY358310-1|AAQ88677.1| 522|Homo sapiens DFLL675 protein. 74 8e-13
AY182024-1|AAO67545.1| 522|Homo sapiens leucine-rich repeat tra... 74 8e-13
AL356953-5|CAI15931.1| 232|Homo sapiens leucine-rich repeat-con... 74 8e-13
AK056644-1|BAB71240.1| 522|Homo sapiens protein ( Homo sapiens ... 74 8e-13
AL512424-2|CAI14256.1| 380|Homo sapiens slit homolog 1 (Drosoph... 74 1e-12
Z24680-1|CAA80847.1| 662|Homo sapiens garp protein. 73 1e-12
DQ084201-1|AAY86708.1| 640|Homo sapiens netrin-G1 ligand splice... 73 1e-12
BC074741-1|AAH74741.1| 345|Homo sapiens leucine-rich repeats an... 73 1e-12
BC070079-1|AAH70079.1| 662|Homo sapiens LRRC32 protein protein. 73 1e-12
BC048421-1|AAH48421.1| 453|Homo sapiens LOC150356 protein protein. 73 1e-12
AY324323-1|AAQ97218.1| 479|Homo sapiens leucine-rich repeat neu... 73 1e-12
AF225421-1|AAG09723.1| 345|Homo sapiens HT017 protein. 73 1e-12
BC101761-1|AAI01762.1| 545|Homo sapiens leucine-rich repeat LGI... 72 4e-12
BC101759-1|AAI01760.1| 545|Homo sapiens leucine-rich repeat LGI... 72 4e-12
AJ487958-1|CAD32305.1| 545|Homo sapiens LGI1-like protein 2 pro... 72 4e-12
AJ487516-1|CAD31784.1| 545|Homo sapiens leucine-rich glioma ina... 72 4e-12
AF467955-1|AAM49553.1| 545|Homo sapiens LGI2 protein. 72 4e-12
AB067503-1|BAB67809.1| 542|Homo sapiens KIAA1916 protein protein. 72 4e-12
L01131-1|AAA52301.1| 347|Homo sapiens decorin protein. 71 5e-12
AB016816-1|BAA74737.1| 1052|Homo sapiens MASL1 protein. 71 5e-12
CR457397-1|CAG33678.1| 708|Homo sapiens LRRN3 protein. 71 7e-12
BC035133-1|AAH35133.1| 708|Homo sapiens leucine rich repeat neu... 71 7e-12
AY358280-1|AAQ88647.1| 708|Homo sapiens LRRN3 protein. 71 7e-12
AF134481-1|AAP97258.1| 708|Homo sapiens leucine-rich repeat pro... 71 7e-12
AB060967-1|BAB47184.1| 708|Homo sapiens neuronal leucine-rich r... 71 7e-12
DQ084202-1|AAY86709.1| 640|Homo sapiens netrin-G1 ligand splice... 71 9e-12
BC111013-1|AAI11014.1| 428|Homo sapiens immunoglobulin superfam... 71 9e-12
BC022478-1|AAH22478.1| 428|Homo sapiens immunoglobulin superfam... 71 9e-12
AY358871-1|AAQ89230.1| 428|Homo sapiens ISLR protein. 71 9e-12
AK223267-1|BAD96987.1| 428|Homo sapiens immunoglobulin superfam... 71 9e-12
AB024537-1|BAA85971.1| 428|Homo sapiens ISLR protein. 71 9e-12
AB024536-1|BAA85970.1| 428|Homo sapiens ISLR protein. 71 9e-12
AB003184-1|BAA22848.1| 428|Homo sapiens ISLR protein. 71 9e-12
BC111745-1|AAI11746.1| 653|Homo sapiens leucine rich repeat con... 70 1e-11
BC111561-1|AAI11562.1| 653|Homo sapiens leucine rich repeat con... 70 1e-11
AY358307-1|AAQ88674.1| 653|Homo sapiens NAG14 protein. 70 1e-11
AK172834-1|BAD18799.1| 459|Homo sapiens protein ( Homo sapiens ... 70 1e-11
AK172751-1|BAD18737.1| 653|Homo sapiens protein ( Homo sapiens ... 70 1e-11
AF196976-1|AAG28019.2| 653|Homo sapiens brain tumor associated ... 70 1e-11
BC101073-1|AAI01074.1| 841|Homo sapiens SLIT and NTRK-like fami... 70 2e-11
BC101072-1|AAI01073.1| 841|Homo sapiens SLIT and NTRK-like fami... 70 2e-11
BC101071-1|AAI01072.1| 841|Homo sapiens SLIT and NTRK-like fami... 70 2e-11
BC101070-1|AAI01071.1| 841|Homo sapiens SLIT and NTRK-like fami... 70 2e-11
AK026427-1|BAB15480.1| 440|Homo sapiens protein ( Homo sapiens ... 70 2e-11
AY358115-1|AAQ88482.1| 593|Homo sapiens DAAT9248 protein. 69 4e-11
AL589765-16|CAI17178.1| 593|Homo sapiens leucine rich repeat ne... 69 4e-11
AJ297858-1|CAC82651.1| 649|Homo sapiens hypothetical protein pr... 69 4e-11
BC101077-1|AAI01078.1| 1041|Homo sapiens toll-like receptor 8 pr... 68 5e-11
BC101076-1|AAI01077.1| 1041|Homo sapiens toll-like receptor 8 pr... 68 5e-11
BC101075-1|AAI01076.1| 1041|Homo sapiens toll-like receptor 8 pr... 68 5e-11
BC101074-1|AAI01075.1| 1041|Homo sapiens toll-like receptor 8 pr... 68 5e-11
BC050445-1|AAH50445.1| 582|Homo sapiens soc-2 suppressor of cle... 68 5e-11
BC003193-1|AAH03193.1| 524|Homo sapiens leucine rich repeat con... 68 5e-11
AY358296-1|AAQ88663.1| 1041|Homo sapiens TLR8 protein. 68 5e-11
AL513211-1|CAI17358.1| 524|Homo sapiens leucine rich repeat con... 68 5e-11
AL158163-3|CAH72813.1| 372|Homo sapiens soc-2 suppressor of cle... 68 5e-11
AL158163-2|CAH72812.1| 582|Homo sapiens soc-2 suppressor of cle... 68 5e-11
AL033384-1|CAI21666.1| 524|Homo sapiens leucine rich repeat con... 68 5e-11
AF359380-1|AAK72246.1| 524|Homo sapiens LANO adaptor protein pr... 68 5e-11
AF332199-1|AAK69623.1| 524|Homo sapiens leucine-rich repeats pr... 68 5e-11
AF246971-1|AAF64061.1| 1059|Homo sapiens Toll-like receptor 8 pr... 68 5e-11
AF245703-1|AAF78036.1| 1041|Homo sapiens toll-like receptor 8 pr... 68 5e-11
AF068920-1|AAC39856.1| 582|Homo sapiens Ras-binding protein SUR... 68 5e-11
AF054828-1|AAC25698.1| 582|Homo sapiens leucine-rich repeat pro... 68 5e-11
AB020669-1|BAA74885.2| 584|Homo sapiens KIAA0862 protein protein. 68 5e-11
AL356953-4|CAI15930.1| 828|Homo sapiens leucine-rich repeat-con... 68 7e-11
AF190501-1|AAG17168.1| 828|Homo sapiens leucine-rich repeat-con... 68 7e-11
BC016048-1|AAH16048.1| 317|Homo sapiens LRRC38 protein protein. 67 9e-11
AL603749-2|CAH70436.1| 294|Homo sapiens leucine rich repeat con... 67 9e-11
AL354712-1|CAI21926.1| 294|Homo sapiens leucine rich repeat con... 67 9e-11
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 67 1e-10
BC126464-1|AAI26465.1| 1371|Homo sapiens erbb2 interacting prote... 67 1e-10
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 67 1e-10
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 67 1e-10
M14219-1|AAB00774.1| 359|Homo sapiens proteoglycan core protein... 66 2e-10
CR541946-1|CAG46744.1| 359|Homo sapiens DCN protein. 66 2e-10
CR407676-1|CAG28604.1| 359|Homo sapiens DCN protein. 66 2e-10
BT019800-1|AAV38603.1| 359|Homo sapiens decorin protein. 66 2e-10
BC128608-1|AAI28609.1| 441|Homo sapiens reticulon 4 receptor-li... 66 2e-10
BC040986-1|AAH40986.1| 837|Homo sapiens SLIT and NTRK-like fami... 66 2e-10
BC005322-1|AAH05322.1| 359|Homo sapiens decorin protein. 66 2e-10
AY250219-1|AAP82836.1| 441|Homo sapiens nogo receptor-like 2 pr... 66 2e-10
AL713693-1|CAD28493.1| 689|Homo sapiens hypothetical protein pr... 66 2e-10
AL080239-3|CAI41650.1| 837|Homo sapiens novel protein protein. 66 2e-10
AK057619-1|BAB71535.1| 469|Homo sapiens protein ( Homo sapiens ... 66 2e-10
AF532859-1|AAP21836.1| 441|Homo sapiens Nogo-66 receptor homolo... 66 2e-10
AF491944-1|AAL92176.1| 359|Homo sapiens decorin protein. 66 2e-10
AF138300-1|AAD44713.1| 359|Homo sapiens decorin variant A protein. 66 2e-10
BC068541-1|AAH68541.1| 713|Homo sapiens leucine rich repeat neu... 66 2e-10
BC034047-1|AAH34047.1| 713|Homo sapiens leucine rich repeat neu... 66 2e-10
AY358290-1|AAQ88657.1| 713|Homo sapiens GAC1 protein. 66 2e-10
AL512306-1|CAI14096.1| 713|Homo sapiens leucine rich repeat neu... 66 2e-10
AF030435-1|AAC39792.1| 713|Homo sapiens glioma amplified on chr... 66 2e-10
DQ355157-1|ABC79623.1| 334|Homo sapiens cytokeratin associated ... 66 3e-10
AY324322-1|AAQ97217.1| 469|Homo sapiens leucine-rich repeat neu... 66 3e-10
AL929554-11|CAH72880.1| 334|Homo sapiens leucine rich repeat co... 66 3e-10
BC087848-1|AAH87848.1| 261|Homo sapiens LGI4 protein protein. 65 4e-10
BC030608-1|AAH30608.1| 661|Homo sapiens podocan protein. 65 4e-10
BC028292-1|AAH28292.1| 402|Homo sapiens PODN protein protein. 65 4e-10
AY358294-1|AAQ88661.1| 642|Homo sapiens EGEE293 protein. 65 4e-10
AY358121-1|AAQ88488.1| 261|Homo sapiens LGI4 protein. 65 4e-10
AJ487959-1|CAD32306.1| 537|Homo sapiens LGI1-like protein 3 pro... 65 4e-10
AJ487519-1|CAD31787.1| 537|Homo sapiens leucine-rich glioma ina... 65 4e-10
AF467954-1|AAM49552.1| 537|Homo sapiens LGI4 protein. 65 4e-10
BC080586-1|AAH80586.1| 743|Homo sapiens MXRA5 protein protein. 65 5e-10
BC064986-1|AAH64986.1| 743|Homo sapiens MXRA5 protein protein. 65 5e-10
BC043165-1|AAH43165.1| 719|Homo sapiens leucine rich repeat and... 65 5e-10
BC011846-1|AAH11846.1| 743|Homo sapiens MXRA5 protein protein. 65 5e-10
BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat con... 65 5e-10
BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein. 65 5e-10
AY313607-1|AAP79898.1| 613|Homo sapiens podocan protein protein. 65 5e-10
AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat con... 65 5e-10
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 65 5e-10
AK055365-1|BAB70910.1| 719|Homo sapiens protein ( Homo sapiens ... 65 5e-10
AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens ... 65 5e-10
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 65 5e-10
BX537976-1|CAD97940.1| 693|Homo sapiens hypothetical protein pr... 64 6e-10
BT007440-1|AAP36108.1| 353|Homo sapiens hypothetical protein, e... 64 6e-10
BC107493-1|AAI07494.1| 699|Homo sapiens extracellular matrix pr... 64 6e-10
BC063114-1|AAH63114.1| 384|Homo sapiens ASPN protein protein. 64 6e-10
BC020975-1|AAH20975.1| 353|Homo sapiens tsukushin protein. 64 6e-10
AY358329-1|AAQ88695.1| 379|Homo sapiens ASPN protein. 64 6e-10
AY358317-1|AAQ88683.1| 353|Homo sapiens E2IG4 protein. 64 6e-10
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 64 6e-10
AY090637-1|AAM09084.1| 320|Homo sapiens tumor endothelial marke... 64 6e-10
AY029191-1|AAK31800.1| 381|Homo sapiens periodontal ligament as... 64 6e-10
AL445183-5|CAH72592.1| 642|Homo sapiens podocan protein. 64 6e-10
AL445183-4|CAH72591.1| 661|Homo sapiens podocan protein. 64 6e-10
AL157827-4|CAI12589.1| 699|Homo sapiens extracellular matrix pr... 64 6e-10
AL137848-5|CAI16697.1| 380|Homo sapiens asporin (LRR class 1) p... 64 6e-10
AL137848-1|CAI16693.1| 699|Homo sapiens extracellular matrix pr... 64 6e-10
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 64 6e-10
AF316824-1|AAK35161.1| 379|Homo sapiens asporin precursor protein. 64 6e-10
AF191019-1|AAF09483.1| 353|Homo sapiens E2IG4 protein. 64 6e-10
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 64 6e-10
AB011792-1|BAA33958.1| 699|Homo sapiens extracellular matrix pr... 64 6e-10
BC022500-1|AAH22500.1| 557|Homo sapiens leucine-rich, glioma in... 64 8e-10
AY358885-1|AAQ89244.1| 557|Homo sapiens LGI1 protein. 64 8e-10
AL358154-2|CAI14982.1| 557|Homo sapiens leucine-rich, glioma in... 64 8e-10
AL358154-1|CAI14981.1| 291|Homo sapiens leucine-rich, glioma in... 64 8e-10
AL157396-3|CAH73838.1| 557|Homo sapiens leucine-rich, glioma in... 64 8e-10
AL157396-2|CAH73837.1| 291|Homo sapiens leucine-rich, glioma in... 64 8e-10
AK027296-1|BAB55022.1| 185|Homo sapiens protein ( Homo sapiens ... 64 8e-10
AF473548-1|AAM22074.1| 291|Homo sapiens leucine-rich glioma ina... 64 8e-10
AF055636-1|AAC99316.1| 557|Homo sapiens leucine-rich glioma-ina... 64 8e-10
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 64 1e-09
U88879-1|AAC34134.1| 904|Homo sapiens Toll-like receptor 3 prot... 63 2e-09
D63481-1|BAA09768.3| 1630|Homo sapiens KIAA0147 protein protein. 63 2e-09
DQ445682-1|ABE01399.1| 904|Homo sapiens Toll-like receptor 3 is... 63 2e-09
BC096335-1|AAH96335.1| 904|Homo sapiens toll-like receptor 3 pr... 63 2e-09
BC096334-1|AAH96334.1| 904|Homo sapiens toll-like receptor 3 pr... 63 2e-09
BC096333-1|AAH96333.1| 904|Homo sapiens toll-like receptor 3 pr... 63 2e-09
BC094737-1|AAH94737.1| 904|Homo sapiens toll-like receptor 3 pr... 63 2e-09
BC059372-1|AAH59372.1| 870|Homo sapiens TLR3 protein protein. 63 2e-09
AY062238-1|AAL38976.1| 1630|Homo sapiens scribble protein. 63 2e-09
AF240677-1|AAP88017.1| 1630|Homo sapiens CRIB1 protein. 63 2e-09
BC114621-1|AAI14622.1| 977|Homo sapiens SLIT and NTRK-like fami... 62 3e-09
AB020655-1|BAA74871.2| 988|Homo sapiens KIAA0848 protein protein. 62 3e-09
BC105958-1|AAI05959.1| 677|Homo sapiens ECM2 protein protein. 62 3e-09
BC103509-1|AAI03510.1| 958|Homo sapiens SLIT and NTRK-like fami... 62 4e-09
BC098287-1|AAH98287.1| 958|Homo sapiens SLIT and NTRK-like fami... 62 4e-09
BC098106-1|AAH98106.1| 958|Homo sapiens SLIT and NTRK-like fami... 62 4e-09
AL603883-1|CAH73026.1| 958|Homo sapiens SLIT and NTRK-like fami... 62 4e-09
AK001637-1|BAA91801.1| 183|Homo sapiens protein ( Homo sapiens ... 62 4e-09
AB020725-1|BAA74941.1| 966|Homo sapiens KIAA0918 protein protein. 62 4e-09
BC117180-1|AAI17181.1| 2527|Homo sapiens leucine-rich repeat kin... 61 6e-09
AY792511-1|AAV63975.1| 2527|Homo sapiens leucine-rich repeat kin... 61 6e-09
BC035645-1|AAH35645.1| 1266|Homo sapiens Similar to RIKEN cDNA 3... 61 8e-09
AY358316-1|AAQ88682.1| 745|Homo sapiens FPLR1885 protein. 61 8e-09
AY358306-1|AAQ88673.1| 616|Homo sapiens GPR125 protein. 61 8e-09
AY358116-1|AAQ88483.1| 548|Homo sapiens LGI3 protein. 61 8e-09
AJ487961-1|CAD32308.1| 548|Homo sapiens LGI1-like protein 4 pro... 61 8e-09
AJ487518-1|CAD31786.1| 548|Homo sapiens leucine-rich glioma ina... 61 8e-09
AF467956-1|AAM49554.1| 548|Homo sapiens LGI3 protein. 61 8e-09
AF051151-1|AAC34376.1| 858|Homo sapiens Toll/interleukin-1 rece... 61 8e-09
AB040898-1|BAA95989.2| 785|Homo sapiens KIAA1465 protein protein. 61 8e-09
BC115015-1|AAI15016.1| 1367|Homo sapiens ERBB2IP protein protein. 60 1e-08
BC115012-1|AAI15013.1| 1371|Homo sapiens erbb2 interacting prote... 60 1e-08
BC109119-1|AAI09120.1| 858|Homo sapiens TLR5 protein protein. 60 1e-08
BC109118-1|AAI09119.1| 858|Homo sapiens TLR5 protein protein. 60 1e-08
BC050692-1|AAH50692.1| 633|Homo sapiens ERBB2IP protein protein. 60 1e-08
AL929091-1|CAM28378.1| 858|Homo sapiens toll-like receptor 5 pr... 60 1e-08
AK027100-1|BAB15657.1| 363|Homo sapiens protein ( Homo sapiens ... 60 1e-08
AF276423-1|AAK69431.1| 1412|Homo sapiens densin-180-like protein... 60 1e-08
AF263744-1|AAF77048.1| 1371|Homo sapiens erbb2-interacting prote... 60 1e-08
AB060695-1|BAB43955.1| 858|Homo sapiens Toll-like receptor 5 pr... 60 1e-08
AB033051-1|BAA86539.2| 1371|Homo sapiens KIAA1225 protein protein. 60 1e-08
Z94160-2|CAI22122.1| 820|Homo sapiens protein ( Human DNA seque... 60 1e-08
BC130290-1|AAI30291.1| 660|Homo sapiens fibronectin leucine ric... 60 1e-08
BC126249-1|AAI26250.1| 660|Homo sapiens fibronectin leucine ric... 60 1e-08
BC071866-1|AAH71866.1| 460|Homo sapiens Unknown (protein for IM... 60 1e-08
BC057786-1|AAH57786.1| 512|Homo sapiens podocan-like 1 protein. 60 1e-08
BC032667-1|AAH32667.1| 352|Homo sapiens keratocan protein. 60 1e-08
BC015581-1|AAH15581.2| 635|Homo sapiens leucine rich repeat and... 60 1e-08
BC007718-1|AAH07718.1| 541|Homo sapiens LRFN4 protein protein. 60 1e-08
AY358287-1|AAQ88654.1| 660|Homo sapiens FLRT2 protein. 60 1e-08
AF205403-1|AAF69126.1| 352|Homo sapiens keratocan protein. 60 1e-08
AF169676-1|AAF28460.1| 660|Homo sapiens leucine-rich repeat tra... 60 1e-08
AF065988-1|AAC17741.1| 352|Homo sapiens keratocan protein. 60 1e-08
AF063301-1|AAC16390.1| 352|Homo sapiens keratan sulfate proteog... 60 1e-08
AB209005-1|BAD92242.1| 622|Homo sapiens leucine rich repeat and... 60 1e-08
AB067491-1|BAB67797.1| 821|Homo sapiens KIAA1904 protein protein. 60 1e-08
AB007865-1|BAA23701.2| 706|Homo sapiens KIAA0405 protein. 60 1e-08
Y19205-1|CAC80724.1| 845|Homo sapiens SLITL1 protein. 60 2e-08
BC113012-1|AAI13013.1| 845|Homo sapiens SLIT and NTRK-like fami... 60 2e-08
BC113011-1|AAI13012.1| 845|Homo sapiens SLIT and NTRK-like fami... 60 2e-08
BC018370-1|AAH18370.1| 674|Homo sapiens fibronectin leucine ric... 60 2e-08
AY358828-1|AAQ89187.1| 733|Homo sapiens LSGV9197 protein. 60 2e-08
AY358308-1|AAQ88675.1| 674|Homo sapiens FLRT1 protein. 60 2e-08
AL109653-2|CAC18888.1| 845|Homo sapiens SLIT and NTRK-like fami... 60 2e-08
AL109653-1|CAI41645.1| 724|Homo sapiens SLIT and NTRK-like fami... 60 2e-08
AK091015-1|BAC03566.1| 724|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AF169675-1|AAF28459.1| 674|Homo sapiens leucine-rich repeat tra... 60 2e-08
AB058757-1|BAB47483.1| 572|Homo sapiens KIAA1854 protein protein. 60 2e-08
M65153-1|AAA52287.1| 394|Homo sapiens biglycan protein. 59 2e-08
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 59 2e-08
M22403-1|AAA52596.1| 626|Homo sapiens platelet membrane glycopr... 58 4e-08
J02940-1|AAA52595.1| 626|Homo sapiens GP1BA protein. 58 4e-08
BC051738-1|AAH51738.1| 696|Homo sapiens SLIT and NTRK-like fami... 58 4e-08
BC027955-1|AAH27955.1| 626|Homo sapiens glycoprotein Ib (platel... 58 4e-08
AY358289-1|AAQ88656.1| 696|Homo sapiens LLWI233 protein. 58 4e-08
AM709890-1|CAM97225.1| 639|Homo sapiens platelet glycoprotein I... 58 4e-08
AL355481-1|CAC37488.1| 696|Homo sapiens SLIT and NTRK-like fami... 58 4e-08
AF395009-1|AAK71325.1| 626|Homo sapiens glycoprotein Ib (platel... 58 4e-08
AB086948-1|BAC10305.1| 626|Homo sapiens platelet glycoprotein I... 58 4e-08
AB067497-1|BAB67803.1| 760|Homo sapiens KIAA1910 protein protein. 58 4e-08
BC125224-1|AAI25225.1| 748|Homo sapiens LRCH2 protein protein. 58 5e-08
BC040732-1|AAH40732.1| 269|Homo sapiens LRTM1 protein protein. 58 5e-08
AL391728-2|CAH73692.1| 1495|Homo sapiens leucine rich repeat con... 58 5e-08
AL391728-1|CAH73691.1| 1537|Homo sapiens leucine rich repeat con... 58 5e-08
AL359412-2|CAH74019.1| 1495|Homo sapiens leucine rich repeat con... 58 5e-08
AL359412-1|CAH74018.1| 1537|Homo sapiens leucine rich repeat con... 58 5e-08
AL158840-2|CAH70975.1| 1495|Homo sapiens leucine rich repeat con... 58 5e-08
AL158840-1|CAH70974.1| 1537|Homo sapiens leucine rich repeat con... 58 5e-08
AL157948-2|CAI22426.1| 1495|Homo sapiens leucine rich repeat con... 58 5e-08
AL157948-1|CAI22425.1| 1537|Homo sapiens leucine rich repeat con... 58 5e-08
AL117353-1|CAI23423.1| 1495|Homo sapiens leucine rich repeat con... 58 5e-08
AK001991-1|BAA92025.1| 273|Homo sapiens protein ( Homo sapiens ... 58 5e-08
AF434715-1|AAL28133.1| 1537|Homo sapiens densin-180 protein. 58 5e-08
AF271734-1|AAP88018.1| 1601|Homo sapiens SCRIB1 variant N1 protein. 58 5e-08
AB038516-1|BAB12038.1| 626|Homo sapiens platelet glycoprotein I... 58 5e-08
CR541787-1|CAG46586.1| 382|Homo sapiens PRELP protein. 57 9e-08
AK095610-1|BAC04589.1| 370|Homo sapiens protein ( Homo sapiens ... 57 9e-08
BC024159-1|AAH24159.2| 858|Homo sapiens leucine rich repeat con... 57 1e-07
AY358874-1|AAQ89233.1| 501|Homo sapiens LRRC5 protein. 57 1e-07
AL391497-3|CAH72226.1| 858|Homo sapiens leucine rich repeat con... 57 1e-07
AK222787-1|BAD96507.1| 671|Homo sapiens leucine rich repeat con... 57 1e-07
AK001332-1|BAA91631.1| 682|Homo sapiens protein ( Homo sapiens ... 57 1e-07
U41344-1|AAC18782.1| 382|Homo sapiens prolargin protein. 56 2e-07
U29089-1|AAC50230.1| 382|Homo sapiens proline- arginine-rich en... 56 2e-07
CR542270-1|CAG47066.1| 382|Homo sapiens PRELP protein. 56 2e-07
BC052210-1|AAH52210.2| 552|Homo sapiens LRRC32 protein protein. 56 2e-07
BC032498-1|AAH32498.1| 382|Homo sapiens proline/arginine-rich e... 56 2e-07
AL391817-1|CAI17033.1| 382|Homo sapiens proline/arginine-rich e... 56 2e-07
BC058935-1|AAH58935.1| 239|Homo sapiens LRRC57 protein protein. 56 2e-07
BC018529-1|AAH18529.3| 683|Homo sapiens leucine-rich repeats an... 56 2e-07
AY358112-1|AAQ88479.1| 802|Homo sapiens ITLT6413 protein. 56 2e-07
AK094891-1|BAC04451.1| 239|Homo sapiens protein ( Homo sapiens ... 56 2e-07
AK094131-1|BAC04294.1| 239|Homo sapiens (EC 2.4.1.101). protein. 56 2e-07
AF053356-12|AAC78793.1| 832|Homo sapiens leucin rich neuronal p... 56 2e-07
J04599-1|AAA36009.1| 368|Homo sapiens protein ( Human hPGI mRNA... 56 3e-07
BT007323-1|AAP35987.1| 368|Homo sapiens biglycan protein. 56 3e-07
BC004244-1|AAH04244.1| 368|Homo sapiens biglycan protein. 56 3e-07
BC002416-1|AAH02416.1| 368|Homo sapiens biglycan protein. 56 3e-07
AY358889-1|AAQ89248.1| 440|Homo sapiens p37NB protein. 56 3e-07
AL122074-1|CAB59249.1| 333|Homo sapiens hypothetical protein pr... 56 3e-07
AK223302-1|BAD97022.1| 368|Homo sapiens biglycan preproprotein ... 56 3e-07
AK222484-1|BAD96204.1| 368|Homo sapiens biglycan preproprotein ... 56 3e-07
AK127729-1|BAC87105.1| 870|Homo sapiens protein ( Homo sapiens ... 56 3e-07
BC027903-1|AAH27903.1| 441|Homo sapiens leucine rich repeat con... 55 4e-07
BC003578-1|AAH03578.1| 628|Homo sapiens leucine rich repeat and... 55 5e-07
AK172754-1|BAD18740.1| 628|Homo sapiens protein ( Homo sapiens ... 55 5e-07
AC073127-2|AAS07483.1| 313|Homo sapiens unknown protein. 55 5e-07
U32907-1|AAB41565.1| 313|Homo sapiens p37NB protein. 54 7e-07
BC126156-1|AAI26157.1| 370|Homo sapiens leucine rich repeat con... 54 7e-07
BC033651-1|AAH33651.1| 1049|Homo sapiens toll-like receptor 7 pr... 54 7e-07
BC009239-1|AAH09239.1| 723|Homo sapiens leucine rich repeat and... 54 7e-07
AY358830-1|AAQ89189.1| 723|Homo sapiens leucine-rich protein pr... 54 7e-07
AY358292-1|AAQ88659.1| 1049|Homo sapiens TLR7 protein. 54 7e-07
AL445222-17|CAH72930.1| 723|Homo sapiens leucine rich repeat an... 54 7e-07
AL445222-16|CAH72931.1| 696|Homo sapiens leucine rich repeat an... 54 7e-07
AK222987-1|BAD96707.1| 370|Homo sapiens leucine rich repeat con... 54 7e-07
AK091589-1|BAC03703.1| 723|Homo sapiens protein ( Homo sapiens ... 54 7e-07
AK056203-1|BAB71119.1| 696|Homo sapiens protein ( Homo sapiens ... 54 7e-07
AK024955-1|BAB15042.1| 370|Homo sapiens protein ( Homo sapiens ... 54 7e-07
AF240467-1|AAF60188.1| 1049|Homo sapiens toll-like receptor 7 pr... 54 7e-07
BC126277-1|AAI26278.1| 1205|Homo sapiens PH domain and leucine r... 54 9e-07
BC082244-1|AAH82244.1| 465|Homo sapiens PHLPP protein protein. 54 9e-07
BC046356-1|AAH46356.1| 421|Homo sapiens osteomodulin protein. 54 9e-07
BC014927-1|AAH14927.3| 1205|Homo sapiens PH domain and leucine r... 54 9e-07
AY358872-1|AAQ89231.1| 421|Homo sapiens OMD protein. 54 9e-07
AL137848-4|CAI16696.1| 421|Homo sapiens osteomodulin protein. 54 9e-07
AK074723-1|BAC11161.1| 546|Homo sapiens protein ( Homo sapiens ... 54 9e-07
AK001924-1|BAA91980.1| 721|Homo sapiens protein ( Homo sapiens ... 54 9e-07
AB011178-1|BAA25532.2| 1369|Homo sapiens KIAA0606 protein protein. 54 9e-07
AB009589-1|BAA23982.1| 421|Homo sapiens Osteomodulin protein. 54 9e-07
AB000114-1|BAA19055.1| 421|Homo sapiens osteomodulin protein. 54 9e-07
AL591063-1|CAI15264.1| 789|Homo sapiens RP11-535K1.2 protein. 54 1e-06
AB033072-1|BAA86560.1| 832|Homo sapiens KIAA1246 protein protein. 54 1e-06
U93091-1|AAC80227.1| 839|Homo sapiens Toll protein homolog prot... 53 2e-06
U88880-1|AAC34135.1| 799|Homo sapiens Toll-like receptor 4 prot... 53 2e-06
BC125270-1|AAI25271.1| 669|Homo sapiens FSHR protein protein. 53 2e-06
BC117422-1|AAI17423.1| 839|Homo sapiens toll-like receptor 4 pr... 53 2e-06
BC114551-1|AAI14552.1| 334|Homo sapiens ISLR2 protein protein. 53 2e-06
BC095477-1|AAH95477.1| 522|Homo sapiens AMIGO2 protein protein. 53 2e-06
BC047595-1|AAH47595.1| 522|Homo sapiens adhesion molecule with ... 53 2e-06
BC007634-1|AAH07634.1| 580|Homo sapiens LRCH4 protein protein. 53 2e-06
AY454159-1|AAR83271.1| 522|Homo sapiens DEGA/AMIGO-2 precursor ... 53 2e-06
AY237005-1|AAO48946.1| 522|Homo sapiens transmembrane protein A... 53 2e-06
AL589786-1|CAH70721.1| 612|Homo sapiens leucine-rich repeats an... 53 2e-06
AL445164-1|CAI43033.1| 612|Homo sapiens leucine-rich repeats an... 53 2e-06
AL160272-2|CAH72619.1| 799|Homo sapiens toll-like receptor 4 pr... 53 2e-06
AL160272-1|CAH72618.1| 839|Homo sapiens toll-like receptor 4 pr... 53 2e-06
AL121878-2|CAI42077.1| 612|Homo sapiens leucine-rich repeats an... 53 2e-06
AF177765-1|AAF05316.1| 839|Homo sapiens toll-like receptor 4 pr... 53 2e-06
AF172171-1|AAF89753.1| 839|Homo sapiens toll-like receptor 4 pr... 53 2e-06
AB080610-1|BAC81189.1| 522|Homo sapiens alivin 1 protein. 53 2e-06
AB040917-1|BAA96008.1| 700|Homo sapiens KIAA1484 protein protein. 53 2e-06
AL513211-2|CAI17359.1| 154|Homo sapiens leucine rich repeat con... 53 2e-06
AL110276-1|CAB53711.1| 242|Homo sapiens hypothetical protein pr... 53 2e-06
AK021896-1|BAB13929.1| 197|Homo sapiens protein ( Homo sapiens ... 53 2e-06
BC051322-1|AAH51322.1| 810|Homo sapiens leucine rich repeat con... 52 3e-06
BC031301-1|AAH31301.1| 583|Homo sapiens leucine rich repeat con... 52 3e-06
AY358286-1|AAQ88653.1| 546|Homo sapiens RQTI221 protein. 52 3e-06
AY358127-1|AAQ88494.1| 627|Homo sapiens AILP5865 protein. 52 3e-06
AY143166-1|AAN18279.1| 810|Homo sapiens leucine-rich repeat-con... 52 3e-06
AL672142-1|CAI10839.1| 810|Homo sapiens leucine rich repeat con... 52 3e-06
AL365330-3|CAI42528.1| 583|Homo sapiens leucine rich repeat con... 52 3e-06
AK027495-1|BAB55153.1| 474|Homo sapiens protein ( Homo sapiens ... 52 3e-06
AB037858-1|BAA92675.1| 811|Homo sapiens KIAA1437 protein protein. 52 3e-06
AB031547-1|BAA95681.1| 623|Homo sapiens retina specific protein... 52 3e-06
S59900-1|AAB26480.1| 695|Homo sapiens follicle stimulating horm... 52 4e-06
M95489-1|AAA52478.1| 695|Homo sapiens follicle stimulating horm... 52 4e-06
BC118548-1|AAI18549.1| 695|Homo sapiens follicle stimulating ho... 52 4e-06
BC096831-1|AAH96831.1| 695|Homo sapiens follicle stimulating ho... 52 4e-06
AY429104-1|AAR07899.1| 695|Homo sapiens follicle stimulating ho... 52 4e-06
BC113973-1|AAI13974.1| 803|Homo sapiens factor for adipocyte di... 52 5e-06
BC035281-1|AAH35281.1| 376|Homo sapiens fibromodulin protein. 52 5e-06
AL359837-1|CAH73821.1| 376|Homo sapiens fibromodulin protein. 52 5e-06
AK000338-1|BAA91094.1| 384|Homo sapiens protein ( Homo sapiens ... 52 5e-06
AF245702-1|AAF78035.1| 1049|Homo sapiens toll-like receptor 7 pr... 52 5e-06
AF138301-1|AAF61437.1| 250|Homo sapiens decorin B protein. 52 5e-06
AB081509-1|BAB86303.1| 803|Homo sapiens AD158 protein. 52 5e-06
BC129927-1|AAI29928.1| 1323|Homo sapiens PH domain and leucine r... 51 6e-06
AK124678-1|BAC85924.1| 423|Homo sapiens protein ( Homo sapiens ... 51 6e-06
AB023148-1|BAA76775.2| 1258|Homo sapiens KIAA0931 protein protein. 51 6e-06
Z29083-1|CAA82324.1| 420|Homo sapiens 5T4 oncofoetal antigen pr... 51 8e-06
X72913-1|CAA51418.1| 376|Homo sapiens fibromodulin protein. 51 8e-06
U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. 51 8e-06
U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot... 51 8e-06
BC037161-1|AAH37161.1| 420|Homo sapiens trophoblast glycoprotei... 51 8e-06
BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D... 51 8e-06
AL359880-1|CAH70792.1| 734|Homo sapiens leucine-rich repeats an... 51 8e-06
AL138704-1|CAH73642.1| 734|Homo sapiens leucine-rich repeats an... 51 8e-06
AL121977-2|CAI21546.1| 420|Homo sapiens trophoblast glycoprotei... 51 8e-06
AK001199-1|BAA91549.1| 221|Homo sapiens protein ( Homo sapiens ... 51 8e-06
AJ012159-1|CAA09930.1| 420|Homo sapiens 5T4 oncofetal trophobla... 51 8e-06
AF177766-1|AAF07823.1| 752|Homo sapiens human toll-like recepto... 51 8e-06
AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va... 51 8e-06
M65085-1|AAA52477.1| 695|Homo sapiens follicle stimulating horm... 50 1e-05
BC117472-1|AAI17473.1| 763|Homo sapiens LRCH1 protein protein. 50 1e-05
BC112937-1|AAI12938.1| 696|Homo sapiens LRCH1 protein protein. 50 1e-05
AY050632-1|AAK95568.1| 728|Homo sapiens neuronal protein isofor... 50 1e-05
AY050631-1|AAK95567.1| 696|Homo sapiens neuronal protein isofor... 50 1e-05
>BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein.
Length = 581
Score = 115 bits (277), Expect = 3e-25
Identities = 85/323 (26%), Positives = 142/323 (43%), Gaps = 6/323 (1%)
Query: 50 IDCMGGELVCAEFPEIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINP 109
++C G +V P + Q+ + + E + P + + + KN ++
Sbjct: 37 VECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISALIALR-----IEKNELSR 91
Query: 110 LNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPL 169
+ AF+ LG + +P+ + + L L L++ + + + F+ L
Sbjct: 92 ITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNL 151
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
K L+L + +PD AF L L +LN+ +N + +I+ F+ L N+ VL L +NR+
Sbjct: 152 KELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTD 211
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
+P G F L L + +N L F ++Q + +SNN L +VF LP L
Sbjct: 212 IPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQL 271
Query: 290 RTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
L L +S++EL P LR L L N + LP +V QL L LS N ++
Sbjct: 272 NRLTLFGNSLKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISF 331
Query: 349 LAPELFADLRALETFVMDGNELQ 371
++P F L L + N LQ
Sbjct: 332 ISPGAFNGLTELRELSLHTNALQ 354
Score = 109 bits (261), Expect = 2e-23
Identities = 70/226 (30%), Positives = 119/226 (52%), Gaps = 3/226 (1%)
Query: 149 RLNAGRNITLHAN--MFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANI 206
+LN G+N H + +F + L+ L L + ++T +P F GL L++L + +N+I +
Sbjct: 177 KLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLL 236
Query: 207 TAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQ 266
+ G F HN+ L L+ N I LP +F P+L LT+ NS + L F + +++
Sbjct: 237 SPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELSPGIFGPMPNLR 296
Query: 267 EIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVL 325
E+ + +N +L + VFSNL L+ L L + I + P F + LR LSL N L+ L
Sbjct: 297 ELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDL 356
Query: 326 PRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
+V R L +++L N + +L +FA++ L + N+L+
Sbjct: 357 DGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLE 402
Score = 97.9 bits (233), Expect = 5e-20
Identities = 65/242 (26%), Positives = 110/242 (45%), Gaps = 1/242 (0%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
KN++ ++ F+ LG ++ T +P+ L L L + L +F
Sbjct: 182 KNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLF 241
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
N L+ L LS+ I+ LP F+ L L +L ++ N + ++ G F + N+ L L
Sbjct: 242 HNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELSPGIFGPMPNLRELWLY 301
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
N I +LP +F++ +L L + RN ++ F GL ++E+ + N L VF
Sbjct: 302 DNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVF 361
Query: 284 SNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS 342
L L+ + L + +R+LP +N + L + L NQL LP + +L L L
Sbjct: 362 RMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGIFDHLGKLCELRLY 421
Query: 343 YN 344
N
Sbjct: 422 DN 423
>BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat
containing 15 protein.
Length = 581
Score = 115 bits (277), Expect = 3e-25
Identities = 85/323 (26%), Positives = 142/323 (43%), Gaps = 6/323 (1%)
Query: 50 IDCMGGELVCAEFPEIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINP 109
++C G +V P + Q+ + + E + P + + + KN ++
Sbjct: 37 VECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISALIALR-----IEKNELSR 91
Query: 110 LNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPL 169
+ AF+ LG + +P+ + + L L L++ + + + F+ L
Sbjct: 92 ITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNL 151
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
K L+L + +PD AF L L +LN+ +N + +I+ F+ L N+ VL L +NR+
Sbjct: 152 KELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTD 211
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
+P G F L L + +N L F ++Q + +SNN L +VF LP L
Sbjct: 212 IPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQL 271
Query: 290 RTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
L L +S++EL P LR L L N + LP +V QL L LS N ++
Sbjct: 272 NRLTLFGNSLKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISF 331
Query: 349 LAPELFADLRALETFVMDGNELQ 371
++P F L L + N LQ
Sbjct: 332 ISPGAFNGLTELRELSLHTNALQ 354
Score = 109 bits (261), Expect = 2e-23
Identities = 70/226 (30%), Positives = 119/226 (52%), Gaps = 3/226 (1%)
Query: 149 RLNAGRNITLHAN--MFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANI 206
+LN G+N H + +F + L+ L L + ++T +P F GL L++L + +N+I +
Sbjct: 177 KLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLL 236
Query: 207 TAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQ 266
+ G F HN+ L L+ N I LP +F P+L LT+ NS + L F + +++
Sbjct: 237 SPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELSPGIFGPMPNLR 296
Query: 267 EIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVL 325
E+ + +N +L + VFSNL L+ L L + I + P F + LR LSL N L+ L
Sbjct: 297 ELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDL 356
Query: 326 PRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
+V R L +++L N + +L +FA++ L + N+L+
Sbjct: 357 DGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLE 402
Score = 97.9 bits (233), Expect = 5e-20
Identities = 65/242 (26%), Positives = 110/242 (45%), Gaps = 1/242 (0%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
KN++ ++ F+ LG ++ T +P+ L L L + L +F
Sbjct: 182 KNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLF 241
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
N L+ L LS+ I+ LP F+ L L +L ++ N + ++ G F + N+ L L
Sbjct: 242 HNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELSPGIFGPMPNLRELWLY 301
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
N I +LP +F++ +L L + RN ++ F GL ++E+ + N L VF
Sbjct: 302 DNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVF 361
Query: 284 SNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS 342
L L+ + L + +R+LP +N + L + L NQL LP + +L L L
Sbjct: 362 RMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGIFDHLGKLCELRLY 421
Query: 343 YN 344
N
Sbjct: 422 DN 423
>AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein.
Length = 581
Score = 114 bits (274), Expect = 6e-25
Identities = 84/323 (26%), Positives = 142/323 (43%), Gaps = 6/323 (1%)
Query: 50 IDCMGGELVCAEFPEIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINP 109
++C G +V P + Q+ + + E + P + + + KN ++
Sbjct: 37 VECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISALIALR-----IEKNELSR 91
Query: 110 LNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPL 169
+ AF+ LG + +P+ + + L L L++ + + + F+ L
Sbjct: 92 ITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNL 151
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
K L+L + +PD AF L L +LN+ +N + +I+ F+ L N+ VL L +NR+
Sbjct: 152 KELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTD 211
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
+P G F L L + +N L F ++Q + +SNN L ++F LP L
Sbjct: 212 IPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQL 271
Query: 290 RTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
L L +S++EL P LR L L N + LP +V QL L LS N ++
Sbjct: 272 NRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISF 331
Query: 349 LAPELFADLRALETFVMDGNELQ 371
++P F L L + N LQ
Sbjct: 332 ISPGAFNGLTELRELSLHTNALQ 354
Score = 109 bits (261), Expect = 2e-23
Identities = 70/226 (30%), Positives = 119/226 (52%), Gaps = 3/226 (1%)
Query: 149 RLNAGRNITLHAN--MFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANI 206
+LN G+N H + +F + L+ L L + ++T +P F GL L++L + +N+I +
Sbjct: 177 KLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLL 236
Query: 207 TAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQ 266
+ G F HN+ L L+ N I LP +F P+L LT+ NS + L F + +++
Sbjct: 237 SPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLR 296
Query: 267 EIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVL 325
E+ + +N +L + VFSNL L+ L L + I + P F + LR LSL N L+ L
Sbjct: 297 ELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDL 356
Query: 326 PRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
+V R L +++L N + +L +FA++ L + N+L+
Sbjct: 357 DGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLE 402
Score = 97.5 bits (232), Expect = 7e-20
Identities = 65/242 (26%), Positives = 110/242 (45%), Gaps = 1/242 (0%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
KN++ ++ F+ LG ++ T +P+ L L L + L +F
Sbjct: 182 KNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLF 241
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
N L+ L LS+ I+ LP F+ L L +L ++ N + ++ G F + N+ L L
Sbjct: 242 HNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLY 301
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
N I +LP +F++ +L L + RN ++ F GL ++E+ + N L VF
Sbjct: 302 DNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVF 361
Query: 284 SNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS 342
L L+ + L + +R+LP +N + L + L NQL LP + +L L L
Sbjct: 362 RMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGIFDHLGKLCELRLY 421
Query: 343 YN 344
N
Sbjct: 422 DN 423
>M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth factor
binding protein complex protein.
Length = 605
Score = 113 bits (273), Expect = 8e-25
Identities = 80/268 (29%), Positives = 122/268 (45%), Gaps = 1/268 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ + AF+ L + G ++ L L L H L + +L FA
Sbjct: 84 NNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFA 143
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
+TP L L LS+ +++ L D F GL L LN+ N +A + AFRGL ++ L L
Sbjct: 144 HTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAG 203
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NR+ L LF+ L L + RN+ R + + F L +Q++ + N+ + F
Sbjct: 204 NRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFL 263
Query: 285 NLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
L ALR L L + + L E+ F LR L L+ N + L + L L L +
Sbjct: 264 GLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGH 323
Query: 344 NAVAELAPELFADLRALETFVMDGNELQ 371
N + +LA F L LE +D N+LQ
Sbjct: 324 NRIRQLAERSFEGLGQLEVLTLDHNQLQ 351
Score = 102 bits (244), Expect = 3e-21
Identities = 72/254 (28%), Positives = 109/254 (42%), Gaps = 1/254 (0%)
Query: 119 GITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAK 178
G T + + ++VP ++L L L G+ +L L +L L +
Sbjct: 74 GGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQ 133
Query: 179 ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFAST 238
+ L F L L + N ++ + G F GL ++ L+L N + LP F
Sbjct: 134 LRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGL 193
Query: 239 PRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSS 298
L L + N YL F GL ++E+ +S N +K VF LP L+ L LD +
Sbjct: 194 GSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNL 253
Query: 299 IREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 357
I + P F+ LR L L+ N++ L G L L LS+NA+A L P F DL
Sbjct: 254 IAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDL 313
Query: 358 RALETFVMDGNELQ 371
LE + N ++
Sbjct: 314 HFLEELQLGHNRIR 327
Score = 100 bits (240), Expect = 8e-21
Identities = 79/271 (29%), Positives = 118/271 (43%), Gaps = 1/271 (0%)
Query: 101 VVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHA 160
V+ N + L F GL + + A + +V LP+L L+ +
Sbjct: 200 VLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAP 259
Query: 161 NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVL 220
F L++L+LS ++ L +D F GL L L + N IA++ F+ LH + L
Sbjct: 260 GAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEEL 319
Query: 221 SLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKE 280
L NRI+ L F +L LT+ N + + + F GL ++ + +S N L E
Sbjct: 320 QLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPE 379
Query: 281 AVFSNLPALRTLQLDLSSI-RELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSL 339
VF L L +L L+ S + R P F S LR L L N L + L G +L L
Sbjct: 380 QVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLEL 439
Query: 340 TLSYNAVAELAPELFADLRALETFVMDGNEL 370
L+ N + L LF L LE ++ N L
Sbjct: 440 DLTSNQLTHLPHRLFQGLGKLEYLLLSRNRL 470
Score = 99 bits (238), Expect = 1e-20
Identities = 74/267 (27%), Positives = 119/267 (44%), Gaps = 1/267 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ L F+GLG + + +P R L L L R L +F+
Sbjct: 156 NRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFS 215
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L+LS + + + F+ L L++L + N IA + GAF GL + L L+
Sbjct: 216 GLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSH 275
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NR+ L F L L + N+ L TF+ L ++E+++ +N L E F
Sbjct: 276 NRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFE 335
Query: 285 NLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
L L L LD + ++E+ F+ + + ++L+ N LR LP V RG +L SL L
Sbjct: 336 GLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEG 395
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
+ + + P F L L + N L
Sbjct: 396 SCLGRIRPHTFTGLSGLRRLFLKDNGL 422
Score = 70.1 bits (164), Expect = 1e-11
Identities = 66/272 (24%), Positives = 114/272 (41%), Gaps = 9/272 (3%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L D F GL ++ + A ++ + L L +L R L F
Sbjct: 276 NRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFE 335
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L L ++ + AFLGL + +N+ N + N+ FRGL + L L
Sbjct: 336 GLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEG 395
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
+ + + F L L + N ++ ++ GL + E+ +++N L +F
Sbjct: 396 SCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQ 455
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSPLRT---LSLARNQLRVLPRSVLRGQTQLTSLTL 341
L L L L + + ELP + + PL+ L ++ N+L LP S+L +L L+L
Sbjct: 456 GLGKLEYLLLSRNRLAELPADAL--GPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSL 513
Query: 342 SYNAVAELAPELFADLRALETFVMDGNELQVG 373
N++ P+ LE ++GN G
Sbjct: 514 RNNSLRTFTPQ----PPGLERLWLEGNPWDCG 541
>BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth factor
binding protein, acid labile subunit protein.
Length = 605
Score = 113 bits (273), Expect = 8e-25
Identities = 80/268 (29%), Positives = 122/268 (45%), Gaps = 1/268 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ + AF+ L + G ++ L L L H L + +L FA
Sbjct: 84 NNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFA 143
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
+TP L L LS+ +++ L D F GL L LN+ N +A + AFRGL ++ L L
Sbjct: 144 HTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAG 203
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NR+ L LF+ L L + RN+ R + + F L +Q++ + N+ + F
Sbjct: 204 NRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFL 263
Query: 285 NLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
L ALR L L + + L E+ F LR L L+ N + L + L L L +
Sbjct: 264 GLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGH 323
Query: 344 NAVAELAPELFADLRALETFVMDGNELQ 371
N + +LA F L LE +D N+LQ
Sbjct: 324 NRIRQLAERSFEGLGQLEVLTLDHNQLQ 351
Score = 102 bits (244), Expect = 3e-21
Identities = 72/254 (28%), Positives = 109/254 (42%), Gaps = 1/254 (0%)
Query: 119 GITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAK 178
G T + + ++VP ++L L L G+ +L L +L L +
Sbjct: 74 GGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQ 133
Query: 179 ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFAST 238
+ L F L L + N ++ + G F GL ++ L+L N + LP F
Sbjct: 134 LRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGL 193
Query: 239 PRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSS 298
L L + N YL F GL ++E+ +S N +K VF LP L+ L LD +
Sbjct: 194 GSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNL 253
Query: 299 IREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 357
I + P F+ LR L L+ N++ L G L L LS+NA+A L P F DL
Sbjct: 254 IAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDL 313
Query: 358 RALETFVMDGNELQ 371
LE + N ++
Sbjct: 314 HFLEELQLGHNRIR 327
Score = 100 bits (239), Expect = 1e-20
Identities = 74/267 (27%), Positives = 119/267 (44%), Gaps = 1/267 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ L F+GLG + + +P R L L L R L +F+
Sbjct: 156 NRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFS 215
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L+LS + + + F+ L L++L + N IA + GAF GL + L L+
Sbjct: 216 GLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSH 275
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NR+ L F L L + N+ L TF+ L ++E+++ +N L E F
Sbjct: 276 NRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFE 335
Query: 285 NLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
L L L LD + ++E+ F+ + + ++L+ N LR LP V RG +L SL L
Sbjct: 336 GLGQLEVLTLDHNQLQEVKAGAFLGLTNMAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEG 395
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
+ + + P F L L + N L
Sbjct: 396 SCLGRIRPHTFTGLSGLRRLFLKDNGL 422
Score = 99 bits (238), Expect = 1e-20
Identities = 79/271 (29%), Positives = 118/271 (43%), Gaps = 1/271 (0%)
Query: 101 VVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHA 160
V+ N + L F GL + + A + +V LP+L L+ +
Sbjct: 200 VLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAP 259
Query: 161 NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVL 220
F L++L+LS ++ L +D F GL L L + N IA++ F+ LH + L
Sbjct: 260 GAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEEL 319
Query: 221 SLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKE 280
L NRI+ L F +L LT+ N + + + F GL ++ + +S N L E
Sbjct: 320 QLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNMAVMNLSGNCLRNLPE 379
Query: 281 AVFSNLPALRTLQLDLSSI-RELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSL 339
VF L L +L L+ S + R P F S LR L L N L + L G +L L
Sbjct: 380 QVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLEL 439
Query: 340 TLSYNAVAELAPELFADLRALETFVMDGNEL 370
L+ N + L LF L LE ++ N L
Sbjct: 440 DLTSNQLTHLPHRLFQGLGKLEYLLLSRNRL 470
Score = 70.5 bits (165), Expect = 9e-12
Identities = 66/272 (24%), Positives = 114/272 (41%), Gaps = 9/272 (3%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L D F GL ++ + A ++ + L L +L R L F
Sbjct: 276 NRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFE 335
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L L ++ + AFLGL + +N+ N + N+ FRGL + L L
Sbjct: 336 GLGQLEVLTLDHNQLQEVKAGAFLGLTNMAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEG 395
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
+ + + F L L + N ++ ++ GL + E+ +++N L +F
Sbjct: 396 SCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQ 455
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSPLRT---LSLARNQLRVLPRSVLRGQTQLTSLTL 341
L L L L + + ELP + + PL+ L ++ N+L LP S+L +L L+L
Sbjct: 456 GLGKLEYLLLSRNRLAELPADAL--GPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSL 513
Query: 342 SYNAVAELAPELFADLRALETFVMDGNELQVG 373
N++ P+ LE ++GN G
Sbjct: 514 RNNSLRTFTPQ----PPGLERLWLEGNPWDCG 541
>AL031724-2|CAC36078.1| 605|Homo sapiens C447E6.2 (insulin-like
growth factor binding protein, acid labile subunit)
protein.
Length = 605
Score = 113 bits (273), Expect = 8e-25
Identities = 80/268 (29%), Positives = 122/268 (45%), Gaps = 1/268 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ + AF+ L + G ++ L L L H L + +L FA
Sbjct: 84 NNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFA 143
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
+TP L L LS+ +++ L D F GL L LN+ N +A + AFRGL ++ L L
Sbjct: 144 HTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAG 203
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NR+ L LF+ L L + RN+ R + + F L +Q++ + N+ + F
Sbjct: 204 NRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFL 263
Query: 285 NLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
L ALR L L + + L E+ F LR L L+ N + L + L L L +
Sbjct: 264 GLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGH 323
Query: 344 NAVAELAPELFADLRALETFVMDGNELQ 371
N + +LA F L LE +D N+LQ
Sbjct: 324 NRIRQLAERSFEGLGQLEVLTLDHNQLQ 351
Score = 102 bits (244), Expect = 3e-21
Identities = 72/254 (28%), Positives = 109/254 (42%), Gaps = 1/254 (0%)
Query: 119 GITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAK 178
G T + + ++VP ++L L L G+ +L L +L L +
Sbjct: 74 GGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQ 133
Query: 179 ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFAST 238
+ L F L L + N ++ + G F GL ++ L+L N + LP F
Sbjct: 134 LRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGL 193
Query: 239 PRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSS 298
L L + N YL F GL ++E+ +S N +K VF LP L+ L LD +
Sbjct: 194 GSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNL 253
Query: 299 IREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 357
I + P F+ LR L L+ N++ L G L L LS+NA+A L P F DL
Sbjct: 254 IAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDL 313
Query: 358 RALETFVMDGNELQ 371
LE + N ++
Sbjct: 314 HFLEELQLGHNRIR 327
Score = 100 bits (240), Expect = 8e-21
Identities = 79/271 (29%), Positives = 118/271 (43%), Gaps = 1/271 (0%)
Query: 101 VVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHA 160
V+ N + L F GL + + A + +V LP+L L+ +
Sbjct: 200 VLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAP 259
Query: 161 NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVL 220
F L++L+LS ++ L +D F GL L L + N IA++ F+ LH + L
Sbjct: 260 GAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEEL 319
Query: 221 SLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKE 280
L NRI+ L F +L LT+ N + + + F GL ++ + +S N L E
Sbjct: 320 QLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPE 379
Query: 281 AVFSNLPALRTLQLDLSSI-RELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSL 339
VF L L +L L+ S + R P F S LR L L N L + L G +L L
Sbjct: 380 QVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLEL 439
Query: 340 TLSYNAVAELAPELFADLRALETFVMDGNEL 370
L+ N + L LF L LE ++ N L
Sbjct: 440 DLTSNQLTHLPHRLFQGLGKLEYLLLSRNRL 470
Score = 99 bits (238), Expect = 1e-20
Identities = 74/267 (27%), Positives = 119/267 (44%), Gaps = 1/267 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ L F+GLG + + +P R L L L R L +F+
Sbjct: 156 NRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFS 215
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L+LS + + + F+ L L++L + N IA + GAF GL + L L+
Sbjct: 216 GLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSH 275
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NR+ L F L L + N+ L TF+ L ++E+++ +N L E F
Sbjct: 276 NRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFE 335
Query: 285 NLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
L L L LD + ++E+ F+ + + ++L+ N LR LP V RG +L SL L
Sbjct: 336 GLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEG 395
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
+ + + P F L L + N L
Sbjct: 396 SCLGRIRPHTFTGLSGLRRLFLKDNGL 422
Score = 70.1 bits (164), Expect = 1e-11
Identities = 66/272 (24%), Positives = 114/272 (41%), Gaps = 9/272 (3%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L D F GL ++ + A ++ + L L +L R L F
Sbjct: 276 NRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFE 335
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L L ++ + AFLGL + +N+ N + N+ FRGL + L L
Sbjct: 336 GLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEG 395
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
+ + + F L L + N ++ ++ GL + E+ +++N L +F
Sbjct: 396 SCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQ 455
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSPLRT---LSLARNQLRVLPRSVLRGQTQLTSLTL 341
L L L L + + ELP + + PL+ L ++ N+L LP S+L +L L+L
Sbjct: 456 GLGKLEYLLLSRNRLAELPADAL--GPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSL 513
Query: 342 SYNAVAELAPELFADLRALETFVMDGNELQVG 373
N++ P+ LE ++GN G
Sbjct: 514 RNNSLRTFTPQ----PPGLERLWLEGNPWDCG 541
>AF192554-1|AAF06774.1| 605|Homo sapiens acid-labile subunit
protein.
Length = 605
Score = 113 bits (273), Expect = 8e-25
Identities = 80/268 (29%), Positives = 122/268 (45%), Gaps = 1/268 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ + AF+ L + G ++ L L L H L + +L FA
Sbjct: 84 NNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFA 143
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
+TP L L LS+ +++ L D F GL L LN+ N +A + AFRGL ++ L L
Sbjct: 144 HTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAG 203
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NR+ L LF+ L L + RN+ R + + F L +Q++ + N+ + F
Sbjct: 204 NRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFL 263
Query: 285 NLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
L ALR L L + + L E+ F LR L L+ N + L + L L L +
Sbjct: 264 GLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGH 323
Query: 344 NAVAELAPELFADLRALETFVMDGNELQ 371
N + +LA F L LE +D N+LQ
Sbjct: 324 NRIRQLAERSFEGLGQLEVLTLDHNQLQ 351
Score = 102 bits (244), Expect = 3e-21
Identities = 72/254 (28%), Positives = 109/254 (42%), Gaps = 1/254 (0%)
Query: 119 GITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAK 178
G T + + ++VP ++L L L G+ +L L +L L +
Sbjct: 74 GGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQ 133
Query: 179 ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFAST 238
+ L F L L + N ++ + G F GL ++ L+L N + LP F
Sbjct: 134 LRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGL 193
Query: 239 PRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSS 298
L L + N YL F GL ++E+ +S N +K VF LP L+ L LD +
Sbjct: 194 GSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNL 253
Query: 299 IREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 357
I + P F+ LR L L+ N++ L G L L LS+NA+A L P F DL
Sbjct: 254 IAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDL 313
Query: 358 RALETFVMDGNELQ 371
LE + N ++
Sbjct: 314 HFLEELQLGHNRIR 327
Score = 100 bits (240), Expect = 8e-21
Identities = 79/271 (29%), Positives = 118/271 (43%), Gaps = 1/271 (0%)
Query: 101 VVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHA 160
V+ N + L F GL + + A + +V LP+L L+ +
Sbjct: 200 VLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAP 259
Query: 161 NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVL 220
F L++L+LS ++ L +D F GL L L + N IA++ F+ LH + L
Sbjct: 260 GAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEEL 319
Query: 221 SLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKE 280
L NRI+ L F +L LT+ N + + + F GL ++ + +S N L E
Sbjct: 320 QLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPE 379
Query: 281 AVFSNLPALRTLQLDLSSI-RELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSL 339
VF L L +L L+ S + R P F S LR L L N L + L G +L L
Sbjct: 380 QVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLEL 439
Query: 340 TLSYNAVAELAPELFADLRALETFVMDGNEL 370
L+ N + L LF L LE ++ N L
Sbjct: 440 DLTSNQLTHLPHRLFQGLGKLEYLLLSRNRL 470
Score = 99 bits (238), Expect = 1e-20
Identities = 74/267 (27%), Positives = 119/267 (44%), Gaps = 1/267 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ L F+GLG + + +P R L L L R L +F+
Sbjct: 156 NRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFS 215
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L+LS + + + F+ L L++L + N IA + GAF GL + L L+
Sbjct: 216 GLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSH 275
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NR+ L F L L + N+ L TF+ L ++E+++ +N L E F
Sbjct: 276 NRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFE 335
Query: 285 NLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
L L L LD + ++E+ F+ + + ++L+ N LR LP V RG +L SL L
Sbjct: 336 GLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEG 395
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
+ + + P F L L + N L
Sbjct: 396 SCLGRIRPHTFTGLSGLRRLFLKDNGL 422
Score = 70.1 bits (164), Expect = 1e-11
Identities = 66/272 (24%), Positives = 114/272 (41%), Gaps = 9/272 (3%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L D F GL ++ + A ++ + L L +L R L F
Sbjct: 276 NRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFE 335
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L L ++ + AFLGL + +N+ N + N+ FRGL + L L
Sbjct: 336 GLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEG 395
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
+ + + F L L + N ++ ++ GL + E+ +++N L +F
Sbjct: 396 SCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQ 455
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSPLRT---LSLARNQLRVLPRSVLRGQTQLTSLTL 341
L L L L + + ELP + + PL+ L ++ N+L LP S+L +L L+L
Sbjct: 456 GLGKLEYLLLSRNRLAELPADAL--GPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSL 513
Query: 342 SYNAVAELAPELFADLRALETFVMDGNELQVG 373
N++ P+ LE ++GN G
Sbjct: 514 RNNSLRTFTPQ----PPGLERLWLEGNPWDCG 541
>BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N,
polypeptide 2 protein.
Length = 545
Score = 105 bits (253), Expect = 2e-22
Identities = 88/342 (25%), Positives = 143/342 (41%), Gaps = 9/342 (2%)
Query: 36 TNLIVGARPRDY--VNIDCMGGELVCAEFP----EIDTPATTQLPSLSLRECSLPPLSCL 89
T+L++ ARP + DC E+ C++ +D P T+ ++ E S L
Sbjct: 10 TSLLLLARPAQPCPMGCDCFVQEVFCSDEELATVPLDIPPYTK--NIIFVETSFTTLETR 67
Query: 90 LQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFR 149
+ K V + DAF GL + + + ++ +L L
Sbjct: 68 AFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLT 127
Query: 150 LNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAG 209
LN L +F + L+ L L ++ LP F L L+ LN+ +N +A +
Sbjct: 128 LNFNMLEALPEGLFQHLAALESLHLQGNRLQALPRRLFQPLTHLKTLNLAQNLLAQLPEE 187
Query: 210 AFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIK 269
F L ++ L L+ N + LP G+F L L + N+ L + F L ++ +
Sbjct: 188 LFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLW 247
Query: 270 ISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRS 328
+ N L ++F++L L L L + +R LP +++P L LSL NQL +
Sbjct: 248 LQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEG 307
Query: 329 VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ L SL LSYNA+ L +F DL L + N L
Sbjct: 308 TFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNL 349
Score = 101 bits (242), Expect = 4e-21
Identities = 77/252 (30%), Positives = 114/252 (45%), Gaps = 1/252 (0%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T ++F + TT+ S P LT + + F P L+ LE++ +
Sbjct: 51 TKNIIFVETSFTTLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFL 110
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
L + F L L +L + N + + G F+ L + L L NR+QALP LF
Sbjct: 111 NLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNRLQALPRRLFQPLTH 170
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIR 300
L L + +N L E F L +Q +K+SNN L + VF L +L+ L LD ++I
Sbjct: 171 LKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNIS 230
Query: 301 ELPEEFISNS-PLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRA 359
ELP + S L L L RN + LP S+ LT L+L +N + L LFA
Sbjct: 231 ELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPC 290
Query: 360 LETFVMDGNELQ 371
L + N+L+
Sbjct: 291 LVGLSLTHNQLE 302
Score = 98.7 bits (235), Expect = 3e-20
Identities = 67/212 (31%), Positives = 101/212 (47%), Gaps = 1/212 (0%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
+P ++ L L +L+ L +F L+ L L I+ LP F L L
Sbjct: 184 LPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCL 243
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
E+L + N I ++ F L N+T LSL N ++ LPAGLFA TP L+ L++ N
Sbjct: 244 ERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLET 303
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPL 312
+ TF L +++ + +S N L +F +L L L L +++ L P F + S L
Sbjct: 304 VAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKL 363
Query: 313 RTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
LSL++NQL LP + L +L L N
Sbjct: 364 ELLSLSKNQLTTLPEGIFDTNYNLFNLALHGN 395
Score = 95.5 bits (227), Expect = 3e-19
Identities = 66/217 (30%), Positives = 103/217 (47%), Gaps = 1/217 (0%)
Query: 157 TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHN 216
TL F + P L + + ++ DAF GL LE L V + N++ F L +
Sbjct: 63 TLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTS 122
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
+ L+LN N ++ALP GLF L +L + N + L F+ L H++ + ++ N+
Sbjct: 123 LGKLTLNFNMLEALPEGLFQHLAALESLHLQGNRLQALPRRLFQPLTHLKTLNLAQNLLA 182
Query: 277 TLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
L E +F L +L+TL+L +++ LP+ F L+ L L N + LP V
Sbjct: 183 QLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFC 242
Query: 336 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 372
L L L NA+ L +FA L L + N L+V
Sbjct: 243 LERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRV 279
Score = 70.5 bits (165), Expect = 9e-12
Identities = 59/218 (27%), Positives = 96/218 (44%), Gaps = 1/218 (0%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
+N + L + F L + + A + +P V L L L++ L +F
Sbjct: 178 QNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVF 237
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
+ L+ L L IT LP F L L L++ N + + AG F + LSL
Sbjct: 238 SQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLT 297
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
N+++ + G FA L +L + N+ +L + FR L+ + ++ + +N L A+F
Sbjct: 298 HNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALF 357
Query: 284 SNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARN 320
NL L L L + + LPE F +N L L+L N
Sbjct: 358 QNLSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGN 395
Score = 62.5 bits (145), Expect = 3e-09
Identities = 42/149 (28%), Positives = 65/149 (43%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
+NAI L F LG + +P + P L L + T+ F
Sbjct: 250 RNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTF 309
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
A+ L+ L LS IT LP F L L +L + N + + F+ L + +LSL+
Sbjct: 310 AHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLS 369
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFR 252
KN++ LP G+F + L NL + N ++
Sbjct: 370 KNQLTTLPEGIFDTNYNLFNLALHGNPWQ 398
>J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precursor
protein.
Length = 545
Score = 105 bits (252), Expect = 3e-22
Identities = 88/342 (25%), Positives = 143/342 (41%), Gaps = 9/342 (2%)
Query: 36 TNLIVGARPRDY--VNIDCMGGELVCAEFP----EIDTPATTQLPSLSLRECSLPPLSCL 89
T+L++ ARP + DC E+ C++ +D P T+ ++ E S L
Sbjct: 10 TSLLLLARPAQPCPMGCDCFVQEVFCSDEELATVPLDIPPYTK--NIIFVETSFTTLETR 67
Query: 90 LQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFR 149
+ K V + DAF GL + + + ++ +L L
Sbjct: 68 AFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLT 127
Query: 150 LNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAG 209
LN L +F + L+ L L ++ LP F L L+ LN+ +N +A +
Sbjct: 128 LNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEE 187
Query: 210 AFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIK 269
F L ++ L L+ N + LP G+F L L + N+ L + F L ++ +
Sbjct: 188 LFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLW 247
Query: 270 ISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRS 328
+ N L ++F++L L L L + +R LP +++P L LSL NQL +
Sbjct: 248 LQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEG 307
Query: 329 VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ L SL LSYNA+ L +F DL L + N L
Sbjct: 308 TFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNL 349
Score = 99 bits (238), Expect = 1e-20
Identities = 76/252 (30%), Positives = 114/252 (45%), Gaps = 1/252 (0%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T ++F + TT+ S P LT + + F P L+ LE++ +
Sbjct: 51 TKNIIFVETSFTTLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFL 110
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
L + F L L +L + N + + G F+ L + L L N++QALP LF
Sbjct: 111 NLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTH 170
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIR 300
L L + +N L E F L +Q +K+SNN L + VF L +L+ L LD ++I
Sbjct: 171 LKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNIS 230
Query: 301 ELPEEFISNS-PLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRA 359
ELP + S L L L RN + LP S+ LT L+L +N + L LFA
Sbjct: 231 ELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPC 290
Query: 360 LETFVMDGNELQ 371
L + N+L+
Sbjct: 291 LVGLSLTHNQLE 302
Score = 98.7 bits (235), Expect = 3e-20
Identities = 67/212 (31%), Positives = 101/212 (47%), Gaps = 1/212 (0%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
+P ++ L L +L+ L +F L+ L L I+ LP F L L
Sbjct: 184 LPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCL 243
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
E+L + N I ++ F L N+T LSL N ++ LPAGLFA TP L+ L++ N
Sbjct: 244 ERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLET 303
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPL 312
+ TF L +++ + +S N L +F +L L L L +++ L P F + S L
Sbjct: 304 VAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKL 363
Query: 313 RTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
LSL++NQL LP + L +L L N
Sbjct: 364 ELLSLSKNQLTTLPEGIFDTNYNLFNLALHGN 395
Score = 95.9 bits (228), Expect = 2e-19
Identities = 66/217 (30%), Positives = 103/217 (47%), Gaps = 1/217 (0%)
Query: 157 TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHN 216
TL F + P L + + ++ DAF GL LE L V + N++ F L +
Sbjct: 63 TLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTS 122
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
+ L+LN N ++ALP GLF L +L + N + L F+ L H++ + ++ N+
Sbjct: 123 LGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLA 182
Query: 277 TLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
L E +F L +L+TL+L +++ LP+ F L+ L L N + LP V
Sbjct: 183 QLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFC 242
Query: 336 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 372
L L L NA+ L +FA L L + N L+V
Sbjct: 243 LERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRV 279
Score = 70.5 bits (165), Expect = 9e-12
Identities = 59/218 (27%), Positives = 96/218 (44%), Gaps = 1/218 (0%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
+N + L + F L + + A + +P V L L L++ L +F
Sbjct: 178 QNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVF 237
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
+ L+ L L IT LP F L L L++ N + + AG F + LSL
Sbjct: 238 SQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLT 297
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
N+++ + G FA L +L + N+ +L + FR L+ + ++ + +N L A+F
Sbjct: 298 HNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALF 357
Query: 284 SNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARN 320
NL L L L + + LPE F +N L L+L N
Sbjct: 358 QNLSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGN 395
Score = 62.5 bits (145), Expect = 3e-09
Identities = 42/149 (28%), Positives = 65/149 (43%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
+NAI L F LG + +P + P L L + T+ F
Sbjct: 250 RNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTF 309
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
A+ L+ L LS IT LP F L L +L + N + + F+ L + +LSL+
Sbjct: 310 AHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLS 369
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFR 252
KN++ LP G+F + L NL + N ++
Sbjct: 370 KNQLTTLPEGIFDTNYNLFNLALHGNPWQ 398
>BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N,
polypeptide 2 protein.
Length = 545
Score = 105 bits (252), Expect = 3e-22
Identities = 88/342 (25%), Positives = 143/342 (41%), Gaps = 9/342 (2%)
Query: 36 TNLIVGARPRDY--VNIDCMGGELVCAEFP----EIDTPATTQLPSLSLRECSLPPLSCL 89
T+L++ ARP + DC E+ C++ +D P T+ ++ E S L
Sbjct: 10 TSLLLLARPAQPCPMGCDCFVQEVFCSDEELATVPLDIPPYTK--NIIFVETSFTTLETR 67
Query: 90 LQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFR 149
+ K V + DAF GL + + + ++ +L L
Sbjct: 68 AFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLT 127
Query: 150 LNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAG 209
LN L +F + L+ L L ++ LP F L L+ LN+ +N +A +
Sbjct: 128 LNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEE 187
Query: 210 AFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIK 269
F L ++ L L+ N + LP G+F L L + N+ L + F L ++ +
Sbjct: 188 LFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLW 247
Query: 270 ISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRS 328
+ N L ++F++L L L L + +R LP +++P L LSL NQL +
Sbjct: 248 LQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEG 307
Query: 329 VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ L SL LSYNA+ L +F DL L + N L
Sbjct: 308 TFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNL 349
Score = 99 bits (238), Expect = 1e-20
Identities = 76/252 (30%), Positives = 114/252 (45%), Gaps = 1/252 (0%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T ++F + TT+ S P LT + + F P L+ LE++ +
Sbjct: 51 TKNIIFVETSFTTLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFL 110
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
L + F L L +L + N + + G F+ L + L L N++QALP LF
Sbjct: 111 NLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTH 170
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIR 300
L L + +N L E F L +Q +K+SNN L + VF L +L+ L LD ++I
Sbjct: 171 LKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNIS 230
Query: 301 ELPEEFISNS-PLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRA 359
ELP + S L L L RN + LP S+ LT L+L +N + L LFA
Sbjct: 231 ELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPC 290
Query: 360 LETFVMDGNELQ 371
L + N+L+
Sbjct: 291 LVGLSLTHNQLE 302
Score = 98.7 bits (235), Expect = 3e-20
Identities = 67/212 (31%), Positives = 101/212 (47%), Gaps = 1/212 (0%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
+P ++ L L +L+ L +F L+ L L I+ LP F L L
Sbjct: 184 LPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCL 243
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
E+L + N I ++ F L N+T LSL N ++ LPAGLFA TP L+ L++ N
Sbjct: 244 ERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLET 303
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPL 312
+ TF L +++ + +S N L +F +L L L L +++ L P F + S L
Sbjct: 304 VAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKL 363
Query: 313 RTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
LSL++NQL LP + L +L L N
Sbjct: 364 ELLSLSKNQLTTLPEGIFDTNYNLFNLALHGN 395
Score = 95.9 bits (228), Expect = 2e-19
Identities = 66/217 (30%), Positives = 103/217 (47%), Gaps = 1/217 (0%)
Query: 157 TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHN 216
TL F + P L + + ++ DAF GL LE L V + N++ F L +
Sbjct: 63 TLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTS 122
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
+ L+LN N ++ALP GLF L +L + N + L F+ L H++ + ++ N+
Sbjct: 123 LGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLA 182
Query: 277 TLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
L E +F L +L+TL+L +++ LP+ F L+ L L N + LP V
Sbjct: 183 QLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFC 242
Query: 336 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 372
L L L NA+ L +FA L L + N L+V
Sbjct: 243 LERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRV 279
Score = 70.5 bits (165), Expect = 9e-12
Identities = 59/218 (27%), Positives = 96/218 (44%), Gaps = 1/218 (0%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
+N + L + F L + + A + +P V L L L++ L +F
Sbjct: 178 QNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVF 237
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
+ L+ L L IT LP F L L L++ N + + AG F + LSL
Sbjct: 238 SQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLT 297
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
N+++ + G FA L +L + N+ +L + FR L+ + ++ + +N L A+F
Sbjct: 298 HNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALF 357
Query: 284 SNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARN 320
NL L L L + + LPE F +N L L+L N
Sbjct: 358 QNLSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGN 395
Score = 62.5 bits (145), Expect = 3e-09
Identities = 42/149 (28%), Positives = 65/149 (43%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
+NAI L F LG + +P + P L L + T+ F
Sbjct: 250 RNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTF 309
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
A+ L+ L LS IT LP F L L +L + N + + F+ L + +LSL+
Sbjct: 310 AHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLS 369
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFR 252
KN++ LP G+F + L NL + N ++
Sbjct: 370 KNQLTTLPEGIFDTNYNLFNLALHGNPWQ 398
>Z23091-1|CAA80637.1| 560|Homo sapiens platelet glycoprotein V
precursor protein.
Length = 560
Score = 102 bits (245), Expect = 2e-21
Identities = 79/270 (29%), Positives = 126/270 (46%), Gaps = 4/270 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNIT-LHANMF 163
NA+ ++ + F+ L + N +P + +L L L+ G N+T L +
Sbjct: 132 NALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLS-GNNLTHLPKGLL 190
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
L+ L L ++ L L L +L N I +I GAF L N++ L+L+
Sbjct: 191 GAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLS 250
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
+N + LP+ LF + L LT+ N L F + +QE+ ++ TL A F
Sbjct: 251 RNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAF 310
Query: 284 SNLPALRTLQLDLSS-IRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTL 341
NL LR L + LS + LP+ F L+ L+L N L LP +LRG +L ++L
Sbjct: 311 RNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSL 370
Query: 342 SYNAVAELAPELFADLRALETFVMDGNELQ 371
N + L LF +L +LE+ +D N+L+
Sbjct: 371 RRNRLRALPRALFRNLSSLESVQLDHNQLE 400
Score = 101 bits (242), Expect = 4e-21
Identities = 73/267 (27%), Positives = 126/267 (47%), Gaps = 2/267 (0%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
+N ++ L A F L L+ + T +P +L + KL L++ R ++L + +
Sbjct: 155 QNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLVSLDSGLL 214
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
+ L L+ I + AF L L L + N +A + + F HN+T+L+L
Sbjct: 215 NSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLF 274
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAV 282
+N + LP LF L L + R R L + FR L ++ + ++ + L+ L +
Sbjct: 275 ENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGA 334
Query: 283 FSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTL 341
F L L+ L L + + LP+ + LR +SL RN+LR LPR++ R + L S+ L
Sbjct: 335 FQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSSLESVQL 394
Query: 342 SYNAVAELAPELFADLRALETFVMDGN 368
+N + L ++F L L ++ N
Sbjct: 395 DHNQLETLPGDVFGALPRLTEVLLGHN 421
Score = 85.8 bits (203), Expect = 2e-16
Identities = 55/191 (28%), Positives = 94/191 (49%), Gaps = 1/191 (0%)
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
VL +F G+ VL++L + ++ I+ + G F L + L L++N+I LP L
Sbjct: 64 VLQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVL 123
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIR 300
L L + N+ R +D F+ L ++QE+ ++ N L ++F+NL L+ L L +++
Sbjct: 124 LEQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLT 183
Query: 301 ELPEEFI-SNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRA 359
LP+ + + + L L L N+L L +L LT L N + +AP F L
Sbjct: 184 HLPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPN 243
Query: 360 LETFVMDGNEL 370
L + + N L
Sbjct: 244 LSSLTLSRNHL 254
Score = 83.0 bits (196), Expect = 2e-15
Identities = 59/224 (26%), Positives = 101/224 (45%), Gaps = 2/224 (0%)
Query: 124 MMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLP 183
++ ++ ++ +L SL LT + + ++ F P L L LS + LP
Sbjct: 199 LLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLP 258
Query: 184 DDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLN 243
FL + L L ++EN +A + F + + L LN+ +++ LPA F + RL
Sbjct: 259 SALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRLRY 318
Query: 244 LTM-MRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL 302
L + + L F+GL +Q + + +N L + + L LR + L + +R L
Sbjct: 319 LGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRAL 378
Query: 303 PEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
P N S L ++ L NQL LP V +LT + L +N+
Sbjct: 379 PRALFRNLSSLESVQLDHNQLETLPGDVFGALPRLTEVLLGHNS 422
Score = 77.0 bits (181), Expect = 1e-13
Identities = 71/253 (28%), Positives = 116/253 (45%), Gaps = 27/253 (10%)
Query: 145 LTHFRL-NAGRNITLHANMFANTPPLKYLELSDA------------------------KI 179
LTH L GR + L + F+ L+ L +SD+ KI
Sbjct: 52 LTHILLFGMGRGV-LQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKI 110
Query: 180 TVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTP 239
T LP + +LEQL + N + I F+ L N+ L+LN+N++ LPA LF +
Sbjct: 111 THLPGALLDKMVLLEQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLE 170
Query: 240 RLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI 299
L L + N+ +L ++ + + +N ++L + ++L AL LQ + I
Sbjct: 171 NLKLLDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHI 230
Query: 300 REL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 358
R + P F L +L+L+RN L LP ++ LT LTL N +AEL LF ++
Sbjct: 231 RSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMG 290
Query: 359 ALETFVMDGNELQ 371
L+ ++ +L+
Sbjct: 291 GLQELWLNRTQLR 303
Score = 76.2 bits (179), Expect = 2e-13
Identities = 64/258 (24%), Positives = 111/258 (43%), Gaps = 5/258 (1%)
Query: 71 TQLPSLSLRECSLPPLSCL---LQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFN 127
T L +L L + S L+ L L A+ + ++ N + L++ LG + F+
Sbjct: 167 TNLENLKLLDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFH 226
Query: 128 AGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAF 187
++ LP L+ L+ L + +F ++ L L L + + LP F
Sbjct: 227 RNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLF 286
Query: 188 LGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN-RIQALPAGLFASTPRLLNLTM 246
+ L++L + ++ + A AFR L + L + + R+ ALP G F L L +
Sbjct: 287 GEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLAL 346
Query: 247 MRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEF 306
N L RGL ++++ + N L A+F NL +L ++QLD + + LP +
Sbjct: 347 HSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSSLESVQLDHNQLETLPGDV 406
Query: 307 ISNSP-LRTLSLARNQLR 323
P L + L N R
Sbjct: 407 FGALPRLTEVLLGHNSWR 424
Score = 74.9 bits (176), Expect = 4e-13
Identities = 62/252 (24%), Positives = 105/252 (41%), Gaps = 1/252 (0%)
Query: 110 LNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPL 169
L + +F G+ + +M + + V L KL RL+ + L + L
Sbjct: 65 LQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLL 124
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+ L L + + + F L L++L + +N++ + A F L N+ +L L+ N +
Sbjct: 125 EQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTH 184
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
LP GL + +L L + N LDS L + E++ N ++ F LP L
Sbjct: 185 LPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNL 244
Query: 290 RTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
+L L + + LP F+ + L L+L N L LP + L L L+ +
Sbjct: 245 SSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRT 304
Query: 349 LAPELFADLRAL 360
L F +L L
Sbjct: 305 LPAAAFRNLSRL 316
>L11238-1|AAA03069.1| 560|Homo sapiens platelet membrane
glycoprotein V protein.
Length = 560
Score = 102 bits (245), Expect = 2e-21
Identities = 79/270 (29%), Positives = 126/270 (46%), Gaps = 4/270 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNIT-LHANMF 163
NA+ ++ + F+ L + N +P + +L L L+ G N+T L +
Sbjct: 132 NALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLS-GNNLTHLPKGLL 190
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
L+ L L ++ L L L +L N I +I GAF L N++ L+L+
Sbjct: 191 GAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLS 250
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
+N + LP+ LF + L LT+ N L F + +QE+ ++ TL A F
Sbjct: 251 RNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAF 310
Query: 284 SNLPALRTLQLDLSS-IRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTL 341
NL LR L + LS + LP+ F L+ L+L N L LP +LRG +L ++L
Sbjct: 311 RNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSL 370
Query: 342 SYNAVAELAPELFADLRALETFVMDGNELQ 371
N + L LF +L +LE+ +D N+L+
Sbjct: 371 RRNRLRALPRALFRNLSSLESVQLDHNQLE 400
Score = 101 bits (242), Expect = 4e-21
Identities = 73/267 (27%), Positives = 126/267 (47%), Gaps = 2/267 (0%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
+N ++ L A F L L+ + T +P +L + KL L++ R ++L + +
Sbjct: 155 QNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLVSLDSGLL 214
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
+ L L+ I + AF L L L + N +A + + F HN+T+L+L
Sbjct: 215 NSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLF 274
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAV 282
+N + LP LF L L + R R L + FR L ++ + ++ + L+ L +
Sbjct: 275 ENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGA 334
Query: 283 FSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTL 341
F L L+ L L + + LP+ + LR +SL RN+LR LPR++ R + L S+ L
Sbjct: 335 FQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSSLESVQL 394
Query: 342 SYNAVAELAPELFADLRALETFVMDGN 368
+N + L ++F L L ++ N
Sbjct: 395 DHNQLETLPGDVFGALPRLTEVLLGHN 421
Score = 85.8 bits (203), Expect = 2e-16
Identities = 55/191 (28%), Positives = 94/191 (49%), Gaps = 1/191 (0%)
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
VL +F G+ VL++L + ++ I+ + G F L + L L++N+I LP L
Sbjct: 64 VLQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVL 123
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIR 300
L L + N+ R +D F+ L ++QE+ ++ N L ++F+NL L+ L L +++
Sbjct: 124 LEQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLT 183
Query: 301 ELPEEFI-SNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRA 359
LP+ + + + L L L N+L L +L LT L N + +AP F L
Sbjct: 184 HLPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPN 243
Query: 360 LETFVMDGNEL 370
L + + N L
Sbjct: 244 LSSLTLSRNHL 254
Score = 83.0 bits (196), Expect = 2e-15
Identities = 59/224 (26%), Positives = 101/224 (45%), Gaps = 2/224 (0%)
Query: 124 MMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLP 183
++ ++ ++ +L SL LT + + ++ F P L L LS + LP
Sbjct: 199 LLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLP 258
Query: 184 DDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLN 243
FL + L L ++EN +A + F + + L LN+ +++ LPA F + RL
Sbjct: 259 SALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRLRY 318
Query: 244 LTM-MRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL 302
L + + L F+GL +Q + + +N L + + L LR + L + +R L
Sbjct: 319 LGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRAL 378
Query: 303 PEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
P N S L ++ L NQL LP V +LT + L +N+
Sbjct: 379 PRALFRNLSSLESVQLDHNQLETLPGDVFGALPRLTEVLLGHNS 422
Score = 77.0 bits (181), Expect = 1e-13
Identities = 71/253 (28%), Positives = 116/253 (45%), Gaps = 27/253 (10%)
Query: 145 LTHFRL-NAGRNITLHANMFANTPPLKYLELSDA------------------------KI 179
LTH L GR + L + F+ L+ L +SD+ KI
Sbjct: 52 LTHILLFGMGRGV-LQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKI 110
Query: 180 TVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTP 239
T LP + +LEQL + N + I F+ L N+ L+LN+N++ LPA LF +
Sbjct: 111 THLPGALLDKMVLLEQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLE 170
Query: 240 RLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI 299
L L + N+ +L ++ + + +N ++L + ++L AL LQ + I
Sbjct: 171 NLKLLDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHI 230
Query: 300 REL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 358
R + P F L +L+L+RN L LP ++ LT LTL N +AEL LF ++
Sbjct: 231 RSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMG 290
Query: 359 ALETFVMDGNELQ 371
L+ ++ +L+
Sbjct: 291 GLQELWLNRTQLR 303
Score = 76.2 bits (179), Expect = 2e-13
Identities = 64/258 (24%), Positives = 111/258 (43%), Gaps = 5/258 (1%)
Query: 71 TQLPSLSLRECSLPPLSCL---LQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFN 127
T L +L L + S L+ L L A+ + ++ N + L++ LG + F+
Sbjct: 167 TNLENLKLLDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFH 226
Query: 128 AGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAF 187
++ LP L+ L+ L + +F ++ L L L + + LP F
Sbjct: 227 RNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLF 286
Query: 188 LGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN-RIQALPAGLFASTPRLLNLTM 246
+ L++L + ++ + A AFR L + L + + R+ ALP G F L L +
Sbjct: 287 GEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLAL 346
Query: 247 MRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEF 306
N L RGL ++++ + N L A+F NL +L ++QLD + + LP +
Sbjct: 347 HSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSSLESVQLDHNQLETLPGDV 406
Query: 307 ISNSP-LRTLSLARNQLR 323
P L + L N R
Sbjct: 407 FGALPRLTEVLLGHNSWR 424
Score = 74.9 bits (176), Expect = 4e-13
Identities = 62/252 (24%), Positives = 105/252 (41%), Gaps = 1/252 (0%)
Query: 110 LNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPL 169
L + +F G+ + +M + + V L KL RL+ + L + L
Sbjct: 65 LQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLL 124
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+ L L + + + F L L++L + +N++ + A F L N+ +L L+ N +
Sbjct: 125 EQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTH 184
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
LP GL + +L L + N LDS L + E++ N ++ F LP L
Sbjct: 185 LPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNL 244
Query: 290 RTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
+L L + + LP F+ + L L+L N L LP + L L L+ +
Sbjct: 245 SSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRT 304
Query: 349 LAPELFADLRAL 360
L F +L L
Sbjct: 305 LPAAAFRNLSRL 316
>BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 99.5 bits (237), Expect = 2e-20
Identities = 77/267 (28%), Positives = 128/267 (47%), Gaps = 5/267 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
NA+ + AF GL ++M VP + L++L L RL+A + + F+
Sbjct: 100 NALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFS 159
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L++L L D +T +P AF L+ L+ + + N+I +I AF L ++ VL L+
Sbjct: 160 GLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHN 219
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRI +L F L L + N+ + R L +++E+ +N + + F
Sbjct: 220 NRIHSLGKKCFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELHFYDNPIQFVGRSAFQ 278
Query: 285 NLPALRTLQLD-LSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+LP LRTL L+ S I E P + + L +L+L Q+ LP++V L L LSY
Sbjct: 279 HLPELRTLTLNGASQITEFP-DLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSY 337
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
N + +L F+ + L+ + NE+
Sbjct: 338 NLLEDLPS--FSVCQKLQKIDLRHNEI 362
Score = 82.6 bits (195), Expect = 2e-15
Identities = 57/202 (28%), Positives = 94/202 (46%), Gaps = 2/202 (0%)
Query: 171 YLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
YL+LS I+ L + L LE+L + N + I GAF GL+++ VL L N+++ +
Sbjct: 70 YLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHV 129
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
P + L +L + N Y+ F GL ++ + + +N + F +L AL+
Sbjct: 130 PTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQ 189
Query: 291 TLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAEL 349
+ L L+ I +P+ N S L L L N++ L + G L +L L+YN + E
Sbjct: 190 AMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF 249
Query: 350 APELFADLRALETFVMDGNELQ 371
P L L+ N +Q
Sbjct: 250 -PTAIRTLSNLKELHFYDNPIQ 270
Score = 81.4 bits (192), Expect = 5e-15
Identities = 62/233 (26%), Positives = 107/233 (45%), Gaps = 3/233 (1%)
Query: 139 LRSLPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
L SL L RL AG +T + F LK L L + ++ +P +A L L+ L
Sbjct: 86 LPSLRFLEELRL-AGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLR 144
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSE 257
+ N I+ + F GLH++ L L+ N + +P F S L +T+ N ++
Sbjct: 145 LDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDY 204
Query: 258 TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSL 317
F L + + + NN +L + F L +L TL L+ +++ E P + S L+ L
Sbjct: 205 AFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELHF 264
Query: 318 ARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
N ++ + RS + +L +LTL+ + P+L LE+ + G ++
Sbjct: 265 YDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGTAN-LESLTLTGAQI 316
Score = 58.8 bits (136), Expect = 3e-08
Identities = 70/278 (25%), Positives = 117/278 (42%), Gaps = 20/278 (7%)
Query: 33 RPSTNLIVGARPRDYVNIDCMGGELVCAEFPEIDTPATTQLPSLSLRECS-LPPLSCLLQ 91
R +L + A YV C G L +D A T++P + R S L ++ L
Sbjct: 138 RSLQSLRLDANHISYVPPSCFSG-LHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALN 196
Query: 92 KVH----------AEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRS 141
K+H + V + N I+ L F GL + N P +R+
Sbjct: 197 KIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPT-AIRT 255
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDA-KITVLPDDAFLGLNVLEQLNVWE 200
L L + + F + P L+ L L+ A +IT PD G LE L +
Sbjct: 256 LSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPD--LTGTANLESLTLTG 313
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
+I+++ L N+ VL L+ N ++ LP+ F+ +L + + N + +TF+
Sbjct: 314 AQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQ 371
Query: 261 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSS 298
L ++ + ++ N + FS LP+L ++LDLSS
Sbjct: 372 QLLSLRSLNLAWNKIAIIHPNAFSTLPSL--IKLDLSS 407
Score = 49.2 bits (112), Expect = 3e-05
Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 9/193 (4%)
Query: 103 FKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANM 162
+ N I + AF+ L + N +Q T D L L L + +L +
Sbjct: 265 YDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPD-LTGTANLESLTLTGAQISSLPQTV 323
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
P L+ L+LS + LP +F L+++++ NEI I F+ L ++ L+L
Sbjct: 324 CNQLPNLQVLDLSYNLLEDLP--SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNL 381
Query: 223 NKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAV 282
N+I + F++ P L+ L + N L S GL + +K++ N L+ +
Sbjct: 382 AWNKIAIIHPNAFSTLPSLIKLDLSSN---LLSSFPITGLHGLTHLKLTGN--HALQSLI 436
Query: 283 FS-NLPALRTLQL 294
S N P L+ +++
Sbjct: 437 SSENFPELKVIEM 449
>BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 99.5 bits (237), Expect = 2e-20
Identities = 77/267 (28%), Positives = 128/267 (47%), Gaps = 5/267 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
NA+ + AF GL ++M VP + L++L L RL+A + + F+
Sbjct: 100 NALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFS 159
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L++L L D +T +P AF L+ L+ + + N+I +I AF L ++ VL L+
Sbjct: 160 GLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHN 219
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRI +L F L L + N+ + R L +++E+ +N + + F
Sbjct: 220 NRIHSLGKKCFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELHFYDNPIQFVGRSAFQ 278
Query: 285 NLPALRTLQLD-LSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+LP LRTL L+ S I E P + + L +L+L Q+ LP++V L L LSY
Sbjct: 279 HLPELRTLTLNGASQITEFP-DLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSY 337
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
N + +L F+ + L+ + NE+
Sbjct: 338 NLLEDLPS--FSVCQKLQKIDLRHNEI 362
Score = 82.6 bits (195), Expect = 2e-15
Identities = 57/202 (28%), Positives = 94/202 (46%), Gaps = 2/202 (0%)
Query: 171 YLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
YL+LS I+ L + L LE+L + N + I GAF GL+++ VL L N+++ +
Sbjct: 70 YLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHV 129
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
P + L +L + N Y+ F GL ++ + + +N + F +L AL+
Sbjct: 130 PTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQ 189
Query: 291 TLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAEL 349
+ L L+ I +P+ N S L L L N++ L + G L +L L+YN + E
Sbjct: 190 AMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF 249
Query: 350 APELFADLRALETFVMDGNELQ 371
P L L+ N +Q
Sbjct: 250 -PTAIRTLSNLKELHFYDNPIQ 270
Score = 81.4 bits (192), Expect = 5e-15
Identities = 62/233 (26%), Positives = 107/233 (45%), Gaps = 3/233 (1%)
Query: 139 LRSLPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
L SL L RL AG +T + F LK L L + ++ +P +A L L+ L
Sbjct: 86 LPSLRFLEELRL-AGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLR 144
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSE 257
+ N I+ + F GLH++ L L+ N + +P F S L +T+ N ++
Sbjct: 145 LDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDY 204
Query: 258 TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSL 317
F L + + + NN +L + F L +L TL L+ +++ E P + S L+ L
Sbjct: 205 AFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELHF 264
Query: 318 ARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
N ++ + RS + +L +LTL+ + P+L LE+ + G ++
Sbjct: 265 YDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGTAN-LESLTLTGAQI 316
Score = 58.8 bits (136), Expect = 3e-08
Identities = 70/278 (25%), Positives = 117/278 (42%), Gaps = 20/278 (7%)
Query: 33 RPSTNLIVGARPRDYVNIDCMGGELVCAEFPEIDTPATTQLPSLSLRECS-LPPLSCLLQ 91
R +L + A YV C G L +D A T++P + R S L ++ L
Sbjct: 138 RSLQSLRLDANHISYVPPSCFSG-LHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALN 196
Query: 92 KVH----------AEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRS 141
K+H + V + N I+ L F GL + N P +R+
Sbjct: 197 KIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPT-AIRT 255
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDA-KITVLPDDAFLGLNVLEQLNVWE 200
L L + + F + P L+ L L+ A +IT PD G LE L +
Sbjct: 256 LSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPD--LTGTANLESLTLTG 313
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
+I+++ L N+ VL L+ N ++ LP+ F+ +L + + N + +TF+
Sbjct: 314 AQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQ 371
Query: 261 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSS 298
L ++ + ++ N + FS LP+L ++LDLSS
Sbjct: 372 QLLSLRSLNLAWNKIAIIHPNAFSTLPSL--IKLDLSS 407
Score = 49.2 bits (112), Expect = 3e-05
Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 9/193 (4%)
Query: 103 FKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANM 162
+ N I + AF+ L + N +Q T D L L L + +L +
Sbjct: 265 YDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPD-LTGTANLESLTLTGAQISSLPQTV 323
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
P L+ L+LS + LP +F L+++++ NEI I F+ L ++ L+L
Sbjct: 324 CNQLPNLQVLDLSYNLLEDLP--SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNL 381
Query: 223 NKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAV 282
N+I + F++ P L+ L + N L S GL + +K++ N L+ +
Sbjct: 382 AWNKIAIIHPNAFSTLPSLIKLDLSSN---LLSSFPITGLHGLTHLKLTGN--HALQSLI 436
Query: 283 FS-NLPALRTLQL 294
S N P L+ +++
Sbjct: 437 SSENFPELKVIEM 449
>BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein.
Length = 927
Score = 99.1 bits (236), Expect = 2e-20
Identities = 71/266 (26%), Positives = 124/266 (46%), Gaps = 3/266 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + + ++A +GL + +A T+VP D L +L H L+ + + +
Sbjct: 91 NQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHHLS 150
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N P L+ L L+ KI+ +PD AF L+ L L++ N+I +++ F GL N+ L LN
Sbjct: 151 NLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNY 210
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N + P + A P L L NS + F G ++ I + +N + + F
Sbjct: 211 NNLGEFPQAIKA-LPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFH 269
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
NL L +L + +S+ + L +L+L ++ +P ++ + Q L +L LSYN
Sbjct: 270 NLSDLHSLVIRGASMVQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYN 329
Query: 345 AVAELAPELFADLRALETFVMDGNEL 370
+ +L F ALE + N++
Sbjct: 330 NIRDLPS--FNGCHALEEISLQRNQI 353
Score = 88.2 bits (209), Expect = 4e-17
Identities = 60/247 (24%), Positives = 114/247 (46%), Gaps = 8/247 (3%)
Query: 152 AGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGA 210
AG +++ +H + LK L L + ++ +P +A GL+ L+ L + N I ++ +
Sbjct: 65 AGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDS 124
Query: 211 FRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKI 270
F GL + L L+ N + +P ++ P L LT+ N + F L + + +
Sbjct: 125 FEGLVQLRHLWLDDNSLTEVPVHHLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHL 184
Query: 271 SNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVL 330
NN +L + F L L TL L+ +++ E P+ + L+ L N + V+P
Sbjct: 185 HNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKALPSLKELGFHSNSISVIPDGAF 244
Query: 331 RGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL------QVGYVYIDDILVAG 384
G L ++ L N ++ + F +L L + V+ G + G V+++ + + G
Sbjct: 245 DGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGTVHLESLTLTG 304
Query: 385 HTRVSMI 391
T++S I
Sbjct: 305 -TKISSI 310
Score = 81.4 bits (192), Expect = 5e-15
Identities = 71/297 (23%), Positives = 127/297 (42%), Gaps = 11/297 (3%)
Query: 80 ECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVL 139
+CS L+ + + + A + N ++ ++ A GL ++ TVP + +
Sbjct: 42 DCSGKGLTAVPEGLSAFTQALQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAI 101
Query: 140 RSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
R L L RL+A ++ + F L++L L D +T +P L L+ L +
Sbjct: 102 RGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHHLSNLPTLQALTLA 161
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
N+I++I AF L ++ VL L+ N+I++L F L L + N+ +
Sbjct: 162 LNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEF-PQAI 220
Query: 260 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLS--- 316
+ L ++E+ +N + + F P LRT+ L + P F+ NS LS
Sbjct: 221 KALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHL-----YDNPLSFVGNSAFHNLSDLH 275
Query: 317 --LARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
+ R V L G L SLTL+ ++ + L + + L T + N ++
Sbjct: 276 SLVIRGASMVQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIR 332
Score = 73.3 bits (172), Expect = 1e-12
Identities = 73/301 (24%), Positives = 121/301 (40%), Gaps = 9/301 (2%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVF---KNAINPLNADAFKGLGI 120
E+ + LP+L +L +S + VV N I L+ F GL
Sbjct: 143 EVPVHHLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDN 202
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
+ N P +++LP L ++ + F P L+ + L D ++
Sbjct: 203 LETLDLNYNNLGEFP-QAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLS 261
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
+ + AF L+ L L + + +H + L+L +I ++P L
Sbjct: 262 FVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGTVH-LESLTLTGTKISSIPNNLCQEQKM 320
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIR 300
L L + N+ R L S F G ++EI + N +KE F L +LR L L + I
Sbjct: 321 LRTLDLSYNNIRDLPS--FNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIH 378
Query: 301 EL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRA 359
E+ F + P+ L ++ N+L P L G QL L ++ LA + F +LR+
Sbjct: 379 EIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQL-KLVGNFKLKEALAAKDFVNLRS 437
Query: 360 L 360
L
Sbjct: 438 L 438
Score = 56.0 bits (129), Expect = 2e-07
Identities = 76/303 (25%), Positives = 119/303 (39%), Gaps = 47/303 (15%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I + D+F+GL + + + T VPV L +LP L L + ++ F
Sbjct: 115 NHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHHLSNLPTLQALTLALNKISSIPDFAFT 174
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N L L L + KI L F GL+ LE L++ N + A + L ++ L +
Sbjct: 175 NLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQ-AIKALPSLKELGFHS 233
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF-----------RGLDHIQEI-KISN 272
N I +P G F P L + + N ++ + F RG +Q+ ++
Sbjct: 234 NSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTG 293
Query: 273 NV---PLTLKEAVFSNLP--------ALRTLQLDLSSIRELP--------EE-------- 305
V LTL S++P LRTL L ++IR+LP EE
Sbjct: 294 TVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEEISLQRNQI 353
Query: 306 -------FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 358
F LR L L+RN + + +T+L +S+N + E L
Sbjct: 354 YQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLN 413
Query: 359 ALE 361
L+
Sbjct: 414 QLK 416
>AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich
repeat-containing G protein-coupled receptor 4 precursor
variant protein.
Length = 1032
Score = 99.1 bits (236), Expect = 2e-20
Identities = 71/266 (26%), Positives = 124/266 (46%), Gaps = 3/266 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + + ++A +GL + +A T+VP D L +L H L+ + + +
Sbjct: 196 NQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLS 255
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N P L+ L L+ KI+ +PD AF L+ L L++ N+I +++ F GL N+ L LN
Sbjct: 256 NLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNY 315
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N + P + A P L L NS + F G ++ I + +N + + F
Sbjct: 316 NNLGEFPQAIKA-LPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFH 374
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
NL L +L + +S+ + L +L+L ++ +P ++ + Q L +L LSYN
Sbjct: 375 NLSDLHSLVIRGASMVQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYN 434
Query: 345 AVAELAPELFADLRALETFVMDGNEL 370
+ +L F ALE + N++
Sbjct: 435 NIRDLPS--FNGCHALEEISLQRNQI 458
Score = 96.3 bits (229), Expect = 2e-19
Identities = 66/267 (24%), Positives = 124/267 (46%), Gaps = 9/267 (3%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGL 190
T +P D ++ P L +L AG +++ +H + LK L L + ++ +P +A GL
Sbjct: 151 TQLPEDAFKNFPFLEELQL-AGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGL 209
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS 250
+ L+ L + N I ++ +F GL + L L+ N + +P ++ P L LT+ N
Sbjct: 210 SALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNK 269
Query: 251 FRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNS 310
+ F L + + + NN +L + F L L TL L+ +++ E P+ +
Sbjct: 270 ISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKALP 329
Query: 311 PLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L+ L N + V+P G L ++ L N ++ + F +L L + V+ G +
Sbjct: 330 SLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASM 389
Query: 371 ------QVGYVYIDDILVAGHTRVSMI 391
G V+++ + + G T++S I
Sbjct: 390 VQQFPNLTGTVHLESLTLTG-TKISSI 415
Score = 91.1 bits (216), Expect = 6e-18
Identities = 59/202 (29%), Positives = 100/202 (49%), Gaps = 2/202 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L++S IT LP+DAF LE+L + N+++ I A GL + VL+L N+++ +P
Sbjct: 143 LDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVP 202
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
+ L +L + N + ++F GL ++ + + +N + SNLP L+
Sbjct: 203 SEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQA 262
Query: 292 LQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L L L+ I +P+ F + S L L L N++R L + G L +L L+YN + E
Sbjct: 263 LTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEF- 321
Query: 351 PELFADLRALETFVMDGNELQV 372
P+ L +L+ N + V
Sbjct: 322 PQAIKALPSLKELGFHSNSISV 343
Score = 85.4 bits (202), Expect = 3e-16
Identities = 71/292 (24%), Positives = 125/292 (42%), Gaps = 3/292 (1%)
Query: 80 ECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVL 139
+CS L+ + + + A + N I L DAFK + + + L
Sbjct: 123 DCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKAL 182
Query: 140 RSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
L +L L + T+ + L+ L L IT +P+D+F GL L L +
Sbjct: 183 SGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLD 242
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
+N + + L + L+L N+I ++P F + L+ L + N R L F
Sbjct: 243 DNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCF 302
Query: 260 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLA 318
GLD+++ + ++ N +A+ LP+L+ L +SI +P+ F N LRT+ L
Sbjct: 303 DGLDNLETLDLNYNNLGEFPQAI-KALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLY 361
Query: 319 RNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
N L + S + L SL + ++ + P L + LE+ + G ++
Sbjct: 362 DNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGTVH-LESLTLTGTKI 412
Score = 73.7 bits (173), Expect = 1e-12
Identities = 73/301 (24%), Positives = 121/301 (40%), Gaps = 9/301 (2%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVF---KNAINPLNADAFKGLGI 120
E+ + LP+L +L +S + VV N I L+ F GL
Sbjct: 248 EVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDN 307
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
+ N P +++LP L ++ + F P L+ + L D ++
Sbjct: 308 LETLDLNYNNLGEFP-QAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLS 366
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
+ + AF L+ L L + + +H + L+L +I ++P L
Sbjct: 367 FVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGTVH-LESLTLTGTKISSIPNNLCQEQKM 425
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIR 300
L L + N+ R L S F G ++EI + N +KE F L +LR L L + I
Sbjct: 426 LRTLDLSYNNIRDLPS--FNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIH 483
Query: 301 EL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRA 359
E+ F + P+ L ++ N+L P L G QL L ++ LA + F +LR+
Sbjct: 484 EIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQL-KLVGNFKLKEALAAKDFVNLRS 542
Query: 360 L 360
L
Sbjct: 543 L 543
Score = 56.4 bits (130), Expect = 2e-07
Identities = 76/303 (25%), Positives = 119/303 (39%), Gaps = 47/303 (15%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I + D+F+GL + + + T VPV L +LP L L + ++ F
Sbjct: 220 NHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFT 279
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N L L L + KI L F GL+ LE L++ N + A + L ++ L +
Sbjct: 280 NLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQ-AIKALPSLKELGFHS 338
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF-----------RGLDHIQEI-KISN 272
N I +P G F P L + + N ++ + F RG +Q+ ++
Sbjct: 339 NSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTG 398
Query: 273 NV---PLTLKEAVFSNLP--------ALRTLQLDLSSIRELP--------EE-------- 305
V LTL S++P LRTL L ++IR+LP EE
Sbjct: 399 TVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEEISLQRNQI 458
Query: 306 -------FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 358
F LR L L+RN + + +T+L +S+N + E L
Sbjct: 459 YQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLN 518
Query: 359 ALE 361
L+
Sbjct: 519 QLK 521
>BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 97.5 bits (232), Expect = 7e-20
Identities = 73/271 (26%), Positives = 122/271 (45%), Gaps = 6/271 (2%)
Query: 105 NAINPLNADAFKGLGITALMM-FNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N + + F L T L++ N + +P + + LP+L H LN + + F
Sbjct: 177 NRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTF 235
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
LK L++ +T L D AF GL+ +E L + N + IT G GL + L L+
Sbjct: 236 QGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLS 295
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
+N I + + +L L + N LD +F GL + + I NN + + F
Sbjct: 296 QNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAF 355
Query: 284 SNLPALRTLQL---DLS-SIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSL 339
L +L+TL L ++S +I ++ F LR L L N++R + + G L L
Sbjct: 356 RGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHL 415
Query: 340 TLSYNAVAELAPELFADLRALETFVMDGNEL 370
LS NA+ L F+ ++ L+ ++ + L
Sbjct: 416 DLSDNAIMSLQGNAFSQMKKLQQLHLNTSSL 446
Score = 79.4 bits (187), Expect = 2e-14
Identities = 53/199 (26%), Positives = 93/199 (46%), Gaps = 3/199 (1%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
+N + L AF GL ++ + T + L L L L+ + + +
Sbjct: 248 RNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAW 307
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
L L+L+ ++ L D +FLGL++L L++ N ++ I AFRGL ++ L L
Sbjct: 308 EFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLK 367
Query: 224 KNRIQAL---PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKE 280
N I G F+ +L L + N R + + F GLD ++ + +S+N ++L+
Sbjct: 368 NNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQG 427
Query: 281 AVFSNLPALRTLQLDLSSI 299
FS + L+ L L+ SS+
Sbjct: 428 NAFSQMKKLQQLHLNTSSL 446
Score = 36.3 bits (80), Expect = 0.19
Identities = 36/141 (25%), Positives = 61/141 (43%), Gaps = 9/141 (6%)
Query: 219 VLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTL 278
+L ++ R+ LP L + RL + N ++ + + L ++E+K++NN T+
Sbjct: 57 LLDCSRKRLARLPEPLPSWVARL---DLSHNRLSFIKASSMSHLQSLREVKLNNNELETI 113
Query: 279 KE--AVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
V +N+ L + I LPE L TL L+ N + L + QL
Sbjct: 114 PNLGPVSANITLLSLAGNRIVEI--LPEHLKEFQSLETLDLSSNNISELQTAF--PALQL 169
Query: 337 TSLTLSYNAVAELAPELFADL 357
L L+ N V + P F +L
Sbjct: 170 KYLYLNSNRVTSMEPGYFDNL 190
Score = 33.5 bits (73), Expect = 1.3
Identities = 17/59 (28%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 312 LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
LR + L N+L +P ++ +T L+L+ N + E+ PE + ++LET + N +
Sbjct: 100 LREVKLNNNELETIP-NLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNI 157
>BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 97.5 bits (232), Expect = 7e-20
Identities = 73/271 (26%), Positives = 122/271 (45%), Gaps = 6/271 (2%)
Query: 105 NAINPLNADAFKGLGITALMM-FNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N + + F L T L++ N + +P + + LP+L H LN + + F
Sbjct: 177 NRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTF 235
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
LK L++ +T L D AF GL+ +E L + N + IT G GL + L L+
Sbjct: 236 QGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLS 295
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
+N I + + +L L + N LD +F GL + + I NN + + F
Sbjct: 296 QNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAF 355
Query: 284 SNLPALRTLQL---DLS-SIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSL 339
L +L+TL L ++S +I ++ F LR L L N++R + + G L L
Sbjct: 356 RGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHL 415
Query: 340 TLSYNAVAELAPELFADLRALETFVMDGNEL 370
LS NA+ L F+ ++ L+ ++ + L
Sbjct: 416 DLSDNAIMSLQGNAFSQMKKLQQLHLNTSSL 446
Score = 79.4 bits (187), Expect = 2e-14
Identities = 53/199 (26%), Positives = 93/199 (46%), Gaps = 3/199 (1%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
+N + L AF GL ++ + T + L L L L+ + + +
Sbjct: 248 RNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAW 307
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
L L+L+ ++ L D +FLGL++L L++ N ++ I AFRGL ++ L L
Sbjct: 308 EFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLK 367
Query: 224 KNRIQAL---PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKE 280
N I G F+ +L L + N R + + F GLD ++ + +S+N ++L+
Sbjct: 368 NNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQG 427
Query: 281 AVFSNLPALRTLQLDLSSI 299
FS + L+ L L+ SS+
Sbjct: 428 NAFSQMKKLQQLHLNTSSL 446
Score = 36.3 bits (80), Expect = 0.19
Identities = 36/141 (25%), Positives = 61/141 (43%), Gaps = 9/141 (6%)
Query: 219 VLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTL 278
+L ++ R+ LP L + RL + N ++ + + L ++E+K++NN T+
Sbjct: 57 LLDCSRKRLARLPEPLPSWVARL---DLSHNRLSFIKASSMSHLQSLREVKLNNNELETI 113
Query: 279 KE--AVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
V +N+ L + I LPE L TL L+ N + L + QL
Sbjct: 114 PNLGPVSANITLLSLAGNRIVEI--LPEHLKEFQSLETLDLSSNNISELQTAF--PALQL 169
Query: 337 TSLTLSYNAVAELAPELFADL 357
L L+ N V + P F +L
Sbjct: 170 KYLYLNSNRVTSMEPGYFDNL 190
Score = 33.5 bits (73), Expect = 1.3
Identities = 17/59 (28%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 312 LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
LR + L N+L +P ++ +T L+L+ N + E+ PE + ++LET + N +
Sbjct: 100 LREVKLNNNELETIP-NLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNI 157
>AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 97.5 bits (232), Expect = 7e-20
Identities = 73/271 (26%), Positives = 122/271 (45%), Gaps = 6/271 (2%)
Query: 105 NAINPLNADAFKGLGITALMM-FNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N + + F L T L++ N + +P + + LP+L H LN + + F
Sbjct: 177 NRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTF 235
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
LK L++ +T L D AF GL+ +E L + N + IT G GL + L L+
Sbjct: 236 QGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLS 295
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
+N I + + +L L + N LD +F GL + + I NN + + F
Sbjct: 296 QNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAF 355
Query: 284 SNLPALRTLQL---DLS-SIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSL 339
L +L+TL L ++S +I ++ F LR L L N++R + + G L L
Sbjct: 356 RGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHL 415
Query: 340 TLSYNAVAELAPELFADLRALETFVMDGNEL 370
LS NA+ L F+ ++ L+ ++ + L
Sbjct: 416 DLSDNAIMSLQGNAFSQMKKLQQLHLNTSSL 446
Score = 79.4 bits (187), Expect = 2e-14
Identities = 53/199 (26%), Positives = 93/199 (46%), Gaps = 3/199 (1%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
+N + L AF GL ++ + T + L L L L+ + + +
Sbjct: 248 RNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAW 307
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
L L+L+ ++ L D +FLGL++L L++ N ++ I AFRGL ++ L L
Sbjct: 308 EFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLK 367
Query: 224 KNRIQAL---PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKE 280
N I G F+ +L L + N R + + F GLD ++ + +S+N ++L+
Sbjct: 368 NNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQG 427
Query: 281 AVFSNLPALRTLQLDLSSI 299
FS + L+ L L+ SS+
Sbjct: 428 NAFSQMKKLQQLHLNTSSL 446
Score = 36.3 bits (80), Expect = 0.19
Identities = 36/141 (25%), Positives = 61/141 (43%), Gaps = 9/141 (6%)
Query: 219 VLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTL 278
+L ++ R+ LP L + RL + N ++ + + L ++E+K++NN T+
Sbjct: 57 LLDCSRKRLARLPEPLPSWVARL---DLSHNRLSFIKASSMSHLQSLREVKLNNNELETI 113
Query: 279 KE--AVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
V +N+ L + I LPE L TL L+ N + L + QL
Sbjct: 114 PNLGPVSANITLLSLAGNRIVEI--LPEHLKEFQSLETLDLSSNNISELQTAF--PALQL 169
Query: 337 TSLTLSYNAVAELAPELFADL 357
L L+ N V + P F +L
Sbjct: 170 KYLYLNSNRVTSMEPGYFDNL 190
Score = 33.5 bits (73), Expect = 1.3
Identities = 17/59 (28%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 312 LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
LR + L N+L +P ++ +T L+L+ N + E+ PE + ++LET + N +
Sbjct: 100 LREVKLNNNELETIP-NLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNI 157
>AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein.
Length = 1059
Score = 97.5 bits (232), Expect = 7e-20
Identities = 73/271 (26%), Positives = 122/271 (45%), Gaps = 6/271 (2%)
Query: 105 NAINPLNADAFKGLGITALMM-FNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N + + F L T L++ N + +P + + LP+L H LN + + F
Sbjct: 117 NRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTF 175
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
LK L++ +T L D AF GL+ +E L + N + IT G GL + L L+
Sbjct: 176 QGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLS 235
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
+N I + + +L L + N LD +F GL + + I NN + + F
Sbjct: 236 QNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAF 295
Query: 284 SNLPALRTLQL---DLS-SIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSL 339
L +L+TL L ++S +I ++ F LR L L N++R + + G L L
Sbjct: 296 RGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHL 355
Query: 340 TLSYNAVAELAPELFADLRALETFVMDGNEL 370
LS NA+ L F+ ++ L+ ++ + L
Sbjct: 356 DLSDNAIMSLQGNAFSQMKKLQQLHLNTSSL 386
Score = 79.4 bits (187), Expect = 2e-14
Identities = 53/199 (26%), Positives = 93/199 (46%), Gaps = 3/199 (1%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
+N + L AF GL ++ + T + L L L L+ + + +
Sbjct: 188 RNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAW 247
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
L L+L+ ++ L D +FLGL++L L++ N ++ I AFRGL ++ L L
Sbjct: 248 EFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLK 307
Query: 224 KNRIQAL---PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKE 280
N I G F+ +L L + N R + + F GLD ++ + +S+N ++L+
Sbjct: 308 NNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQG 367
Query: 281 AVFSNLPALRTLQLDLSSI 299
FS + L+ L L+ SS+
Sbjct: 368 NAFSQMKKLQQLHLNTSSL 386
Score = 37.9 bits (84), Expect = 0.062
Identities = 27/89 (30%), Positives = 50/89 (56%), Gaps = 2/89 (2%)
Query: 262 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 321
L HI +S+N +K + S+L +LR ++L+ + + +P ++ + LSLA N+
Sbjct: 13 LFHISRPDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNR 72
Query: 322 L-RVLPRSVLRGQTQLTSLTLSYNAVAEL 349
+ +LP + Q+ L +L LS N ++EL
Sbjct: 73 IVEILPEHLKEFQS-LETLDLSSNNISEL 100
Score = 33.5 bits (73), Expect = 1.3
Identities = 17/59 (28%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 312 LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
LR + L N+L +P ++ +T L+L+ N + E+ PE + ++LET + N +
Sbjct: 40 LREVKLNNNELETIP-NLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNI 97
Score = 32.3 bits (70), Expect = 3.1
Identities = 29/114 (25%), Positives = 49/114 (42%), Gaps = 6/114 (5%)
Query: 246 MMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKE--AVFSNLPALRTLQLDLSSIRELP 303
+ N ++ + + L ++E+K++NN T+ V +N+ L + I LP
Sbjct: 21 LSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEI--LP 78
Query: 304 EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 357
E L TL L+ N + L + QL L L+ N V + P F +L
Sbjct: 79 EHLKEFQSLETLDLSSNNISELQTAF--PALQLKYLYLNSNRVTSMEPGYFDNL 130
>AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein.
Length = 1119
Score = 97.5 bits (232), Expect = 7e-20
Identities = 73/271 (26%), Positives = 122/271 (45%), Gaps = 6/271 (2%)
Query: 105 NAINPLNADAFKGLGITALMM-FNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N + + F L T L++ N + +P + + LP+L H LN + + F
Sbjct: 177 NRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTF 235
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
LK L++ +T L D AF GL+ +E L + N + IT G GL + L L+
Sbjct: 236 QGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLS 295
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
+N I + + +L L + N LD +F GL + + I NN + + F
Sbjct: 296 QNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAF 355
Query: 284 SNLPALRTLQL---DLS-SIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSL 339
L +L+TL L ++S +I ++ F LR L L N++R + + G L L
Sbjct: 356 RGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHL 415
Query: 340 TLSYNAVAELAPELFADLRALETFVMDGNEL 370
LS NA+ L F+ ++ L+ ++ + L
Sbjct: 416 DLSDNAIMSLQGNAFSQMKKLQQLHLNTSSL 446
Score = 79.4 bits (187), Expect = 2e-14
Identities = 53/199 (26%), Positives = 93/199 (46%), Gaps = 3/199 (1%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
+N + L AF GL ++ + T + L L L L+ + + +
Sbjct: 248 RNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAW 307
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
L L+L+ ++ L D +FLGL++L L++ N ++ I AFRGL ++ L L
Sbjct: 308 EFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLK 367
Query: 224 KNRIQAL---PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKE 280
N I G F+ +L L + N R + + F GLD ++ + +S+N ++L+
Sbjct: 368 NNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQG 427
Query: 281 AVFSNLPALRTLQLDLSSI 299
FS + L+ L L+ SS+
Sbjct: 428 NAFSQMKKLQQLHLNTSSL 446
Score = 36.3 bits (80), Expect = 0.19
Identities = 36/141 (25%), Positives = 61/141 (43%), Gaps = 9/141 (6%)
Query: 219 VLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTL 278
+L ++ R+ LP L + RL + N ++ + + L ++E+K++NN T+
Sbjct: 57 LLDCSRKRLARLPEPLPSWVARL---DLSHNRLSFIKASSMSHLQSLREVKLNNNELETI 113
Query: 279 KE--AVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
V +N+ L + I LPE L TL L+ N + L + QL
Sbjct: 114 PNLGPVSANITLLSLAGNRIVEI--LPEHLKEFQSLETLDLSSNNISELQTAF--PALQL 169
Query: 337 TSLTLSYNAVAELAPELFADL 357
L L+ N V + P F +L
Sbjct: 170 KYLYLNSNRVTSMEPGYFDNL 190
Score = 33.5 bits (73), Expect = 1.3
Identities = 17/59 (28%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 312 LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
LR + L N+L +P ++ +T L+L+ N + E+ PE + ++LET + N +
Sbjct: 100 LREVKLNNNELETIP-NLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNI 157
>AF346711-1|AAK31153.1| 951|Homo sapiens G-protein couple receptor
protein.
Length = 951
Score = 96.7 bits (230), Expect = 1e-19
Identities = 70/266 (26%), Positives = 123/266 (46%), Gaps = 3/266 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + + ++A +GL + +A T+VP D L +L H L+ + + +
Sbjct: 115 NQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLS 174
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N P L+ L L+ KI+ +PD AF L+ L L++ N+I ++ F GL N+ L L+
Sbjct: 175 NLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSY 234
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N + P + A P L L NS + F G ++ I + +N + + F
Sbjct: 235 NNLGEFPQAIKA-RPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFH 293
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
NL L +L + +S+ + L +L+L ++ +P ++ + Q L +L LSYN
Sbjct: 294 NLSDLHSLVIRGASMVQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYN 353
Query: 345 AVAELAPELFADLRALETFVMDGNEL 370
+ +L F ALE + N++
Sbjct: 354 NIRDLPS--FNGCHALEEISLQRNQI 377
Score = 95.9 bits (228), Expect = 2e-19
Identities = 66/267 (24%), Positives = 122/267 (45%), Gaps = 9/267 (3%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGL 190
T +P D ++ P L +L AG +++ +H + LK L L + ++ +P +A GL
Sbjct: 70 TQLPEDAFKNFPFLEELQL-AGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGL 128
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS 250
+ L+ L + N I ++ +F GL + L L+ N + +P ++ P L LT+ N
Sbjct: 129 SALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNK 188
Query: 251 FRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNS 310
+ F L + + + NN L + F L L TL L +++ E P+ +
Sbjct: 189 ISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFPQAIKARP 248
Query: 311 PLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L+ L N + V+P G L ++ L N ++ + F +L L + V+ G +
Sbjct: 249 SLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASM 308
Query: 371 ------QVGYVYIDDILVAGHTRVSMI 391
G V+++ + + G T++S I
Sbjct: 309 VQQFPNLTGTVHLESLTLTG-TKISSI 334
Score = 89.4 bits (212), Expect = 2e-17
Identities = 59/202 (29%), Positives = 99/202 (49%), Gaps = 2/202 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L++S IT LP+DAF LE+L + N+++ I A GL + VL+L N+++ +P
Sbjct: 62 LDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVP 121
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
+ L +L + N + ++F GL ++ + + +N + SNLP L+
Sbjct: 122 SEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQA 181
Query: 292 LQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L L L+ I +P+ F + S L L L N++R L + G L +L LSYN + E
Sbjct: 182 LTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEF- 240
Query: 351 PELFADLRALETFVMDGNELQV 372
P+ +L+ N + V
Sbjct: 241 PQAIKARPSLKELGFHSNSISV 262
Score = 84.6 bits (200), Expect = 5e-16
Identities = 71/292 (24%), Positives = 125/292 (42%), Gaps = 3/292 (1%)
Query: 80 ECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVL 139
+CS L+ + + + A + N I L DAFK + + + L
Sbjct: 42 DCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKAL 101
Query: 140 RSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
L +L L + T+ + L+ L L IT +P+D+F GL L L +
Sbjct: 102 SGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLD 161
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
+N + + L + L+L N+I ++P F + L+ L + N R L F
Sbjct: 162 DNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCF 221
Query: 260 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLA 318
GLD+++ + +S N +A+ + P+L+ L +SI +P+ F N LRT+ L
Sbjct: 222 DGLDNLETLDLSYNNLGEFPQAIKAR-PSLKELGFHSNSISVIPDGAFDGNPLLRTIHLY 280
Query: 319 RNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
N L + S + L SL + ++ + P L + LE+ + G ++
Sbjct: 281 DNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGTVH-LESLTLTGTKI 331
Score = 68.9 bits (161), Expect = 3e-11
Identities = 71/301 (23%), Positives = 120/301 (39%), Gaps = 9/301 (2%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVF---KNAINPLNADAFKGLGI 120
E+ + LP+L +L +S + VV N I L+ F GL
Sbjct: 167 EVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDN 226
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
+ + P +++ P L ++ + F P L+ + L D ++
Sbjct: 227 LETLDLSYNNLGEFP-QAIKARPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLS 285
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
+ + AF L+ L L + + +H + L+L +I ++P L
Sbjct: 286 FVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGTVH-LESLTLTGTKISSIPNNLCQEQKM 344
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIR 300
L L + N+ R L S F G ++EI + N +KE F L +LR L L + I
Sbjct: 345 LRTLDLSYNNIRDLPS--FNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIH 402
Query: 301 EL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRA 359
E+ F + P+ L ++ N+L P L G QL L ++ LA + F +LR+
Sbjct: 403 EIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQL-KLVGNFKLKEALAAKDFVNLRS 461
Query: 360 L 360
L
Sbjct: 462 L 462
Score = 54.0 bits (124), Expect = 9e-07
Identities = 75/303 (24%), Positives = 118/303 (38%), Gaps = 47/303 (15%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I + D+F+GL + + + T VPV L +LP L L + ++ F
Sbjct: 139 NHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFT 198
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N L L L + KI L F GL+ LE L++ N + A + ++ L +
Sbjct: 199 NLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFPQ-AIKARPSLKELGFHS 257
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF-----------RGLDHIQEI-KISN 272
N I +P G F P L + + N ++ + F RG +Q+ ++
Sbjct: 258 NSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTG 317
Query: 273 NV---PLTLKEAVFSNLP--------ALRTLQLDLSSIRELP--------EE-------- 305
V LTL S++P LRTL L ++IR+LP EE
Sbjct: 318 TVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEEISLQRNQI 377
Query: 306 -------FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 358
F LR L L+RN + + +T+L +S+N + E L
Sbjct: 378 YQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLN 437
Query: 359 ALE 361
L+
Sbjct: 438 QLK 440
>AL159161-1|CAI17102.1| 754|Homo sapiens relaxin/insulin-like
family peptide receptor 2 protein.
Length = 754
Score = 96.3 bits (229), Expect = 2e-19
Identities = 63/200 (31%), Positives = 96/200 (48%), Gaps = 1/200 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L KI LPD F+ L+++ + N I +I+ AF GL N+ +L LN N I L
Sbjct: 142 LSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLR 201
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
G+F +L L + N + F GL+ + + + NN L + + + +P L
Sbjct: 202 PGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNW 261
Query: 292 LQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
+ L+ + I+ L F+S L L L RNQ+ +P L L LS N + EL+
Sbjct: 262 VDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELS 321
Query: 351 PELFADLRALETFVMDGNEL 370
P LF DL+ L+ + N L
Sbjct: 322 PHLFKDLKLLQKLNLSSNPL 341
Score = 72.5 bits (170), Expect = 2e-12
Identities = 62/267 (23%), Positives = 114/267 (42%), Gaps = 3/267 (1%)
Query: 51 DCMGGELVCAEFPEIDTPA-TTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINP 109
DC EL C P + + LSL++ + L + + + K + N I
Sbjct: 116 DCKETELECVNGDLKSVPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRH 175
Query: 110 LNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPL 169
++ AF GL ++ N TT+ + + L +LT L+ + +F L
Sbjct: 176 ISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSL 235
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+L + + + LP + L +++ N I +T F ++TVL L +N+I
Sbjct: 236 FFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGF 295
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
+P F+S L L + N+ L F+ L +Q++ +S+N + L + F +L L
Sbjct: 296 VPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQL 355
Query: 290 RTLQLDLSSIRELPEEFISNSPLRTLS 316
++L L+ I + P++ LS
Sbjct: 356 QSLDLERIEIPNINTRMF--QPMKNLS 380
Score = 47.6 bits (108), Expect = 8e-05
Identities = 37/168 (22%), Positives = 69/168 (41%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I ++ F GL + +P + +P+L L R L + F
Sbjct: 219 NPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFL 278
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
+ L L L +I +P+ F L L +L++ N I ++ F+ L + L+L+
Sbjct: 279 SCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSS 338
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISN 272
N + L F S +L +L + R +++ F+ + ++ I N
Sbjct: 339 NPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLSHIYFKN 386
>AL138708-1|CAH73785.1| 754|Homo sapiens relaxin/insulin-like
family peptide receptor 2 protein.
Length = 754
Score = 96.3 bits (229), Expect = 2e-19
Identities = 63/200 (31%), Positives = 96/200 (48%), Gaps = 1/200 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L KI LPD F+ L+++ + N I +I+ AF GL N+ +L LN N I L
Sbjct: 142 LSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLR 201
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
G+F +L L + N + F GL+ + + + NN L + + + +P L
Sbjct: 202 PGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNW 261
Query: 292 LQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
+ L+ + I+ L F+S L L L RNQ+ +P L L LS N + EL+
Sbjct: 262 VDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELS 321
Query: 351 PELFADLRALETFVMDGNEL 370
P LF DL+ L+ + N L
Sbjct: 322 PHLFKDLKLLQKLNLSSNPL 341
Score = 72.5 bits (170), Expect = 2e-12
Identities = 62/267 (23%), Positives = 114/267 (42%), Gaps = 3/267 (1%)
Query: 51 DCMGGELVCAEFPEIDTPA-TTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINP 109
DC EL C P + + LSL++ + L + + + K + N I
Sbjct: 116 DCKETELECVNGDLKSVPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRH 175
Query: 110 LNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPL 169
++ AF GL ++ N TT+ + + L +LT L+ + +F L
Sbjct: 176 ISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSL 235
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+L + + + LP + L +++ N I +T F ++TVL L +N+I
Sbjct: 236 FFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGF 295
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
+P F+S L L + N+ L F+ L +Q++ +S+N + L + F +L L
Sbjct: 296 VPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQL 355
Query: 290 RTLQLDLSSIRELPEEFISNSPLRTLS 316
++L L+ I + P++ LS
Sbjct: 356 QSLDLERIEIPNINTRMF--QPMKNLS 380
Score = 47.6 bits (108), Expect = 8e-05
Identities = 37/168 (22%), Positives = 69/168 (41%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I ++ F GL + +P + +P+L L R L + F
Sbjct: 219 NPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFL 278
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
+ L L L +I +P+ F L L +L++ N I ++ F+ L + L+L+
Sbjct: 279 SCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSS 338
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISN 272
N + L F S +L +L + R +++ F+ + ++ I N
Sbjct: 339 NPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLSHIYFKN 386
>AF453828-1|AAL73946.1| 754|Homo sapiens G protein-coupled receptor
affecting testicular descent protein.
Length = 754
Score = 96.3 bits (229), Expect = 2e-19
Identities = 63/200 (31%), Positives = 96/200 (48%), Gaps = 1/200 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L KI LPD F+ L+++ + N I +I+ AF GL N+ +L LN N I L
Sbjct: 142 LSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLR 201
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
G+F +L L + N + F GL+ + + + NN L + + + +P L
Sbjct: 202 PGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNW 261
Query: 292 LQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
+ L+ + I+ L F+S L L L RNQ+ +P L L LS N + EL+
Sbjct: 262 VDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELS 321
Query: 351 PELFADLRALETFVMDGNEL 370
P LF DL+ L+ + N L
Sbjct: 322 PHLFKDLKLLQKLNLSSNPL 341
Score = 72.5 bits (170), Expect = 2e-12
Identities = 62/267 (23%), Positives = 114/267 (42%), Gaps = 3/267 (1%)
Query: 51 DCMGGELVCAEFPEIDTPA-TTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINP 109
DC EL C P + + LSL++ + L + + + K + N I
Sbjct: 116 DCKETELECVNGDLKSVPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRH 175
Query: 110 LNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPL 169
++ AF GL ++ N TT+ + + L +LT L+ + +F L
Sbjct: 176 ISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSL 235
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+L + + + LP + L +++ N I +T F ++TVL L +N+I
Sbjct: 236 FFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGF 295
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
+P F+S L L + N+ L F+ L +Q++ +S+N + L + F +L L
Sbjct: 296 VPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQL 355
Query: 290 RTLQLDLSSIRELPEEFISNSPLRTLS 316
++L L+ I + P++ LS
Sbjct: 356 QSLDLERIEIPNINTRMF--QPMKNLS 380
Score = 47.6 bits (108), Expect = 8e-05
Identities = 37/168 (22%), Positives = 69/168 (41%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I ++ F GL + +P + +P+L L R L + F
Sbjct: 219 NPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFL 278
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
+ L L L +I +P+ F L L +L++ N I ++ F+ L + L+L+
Sbjct: 279 SCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSS 338
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISN 272
N + L F S +L +L + R +++ F+ + ++ I N
Sbjct: 339 NPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLSHIYFKN 386
>AF403384-1|AAL69324.2| 754|Homo sapiens LGR8 protein.
Length = 754
Score = 96.3 bits (229), Expect = 2e-19
Identities = 63/200 (31%), Positives = 96/200 (48%), Gaps = 1/200 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L KI LPD F+ L+++ + N I +I+ AF GL N+ +L LN N I L
Sbjct: 142 LSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLR 201
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
G+F +L L + N + F GL+ + + + NN L + + + +P L
Sbjct: 202 PGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNW 261
Query: 292 LQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
+ L+ + I+ L F+S L L L RNQ+ +P L L LS N + EL+
Sbjct: 262 VDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELS 321
Query: 351 PELFADLRALETFVMDGNEL 370
P LF DL+ L+ + N L
Sbjct: 322 PHLFKDLKLLQKLNLSSNPL 341
Score = 72.5 bits (170), Expect = 2e-12
Identities = 62/267 (23%), Positives = 114/267 (42%), Gaps = 3/267 (1%)
Query: 51 DCMGGELVCAEFPEIDTPA-TTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINP 109
DC EL C P + + LSL++ + L + + + K + N I
Sbjct: 116 DCKETELECVNGDLKSVPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRH 175
Query: 110 LNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPL 169
++ AF GL ++ N TT+ + + L +LT L+ + +F L
Sbjct: 176 ISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSL 235
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+L + + + LP + L +++ N I +T F ++TVL L +N+I
Sbjct: 236 FFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGF 295
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
+P F+S L L + N+ L F+ L +Q++ +S+N + L + F +L L
Sbjct: 296 VPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQL 355
Query: 290 RTLQLDLSSIRELPEEFISNSPLRTLS 316
++L L+ I + P++ LS
Sbjct: 356 QSLDLERIEIPNINTRMF--QPMKNLS 380
Score = 47.6 bits (108), Expect = 8e-05
Identities = 37/168 (22%), Positives = 69/168 (41%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I ++ F GL + +P + +P+L L R L + F
Sbjct: 219 NPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFL 278
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
+ L L L +I +P+ F L L +L++ N I ++ F+ L + L+L+
Sbjct: 279 SCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSS 338
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISN 272
N + L F S +L +L + R +++ F+ + ++ I N
Sbjct: 339 NPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLSHIYFKN 386
>BC040188-1|AAH40188.1| 692|Homo sapiens LOC150356 protein protein.
Length = 692
Score = 95.5 bits (227), Expect = 3e-19
Identities = 69/237 (29%), Positives = 110/237 (46%), Gaps = 4/237 (1%)
Query: 137 DVLRSLPKLTHFRLNAGRNI--TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLE 194
+V ++P+LT RL+ N+ + A F P L +L+L ++ ++ + AF GL L
Sbjct: 61 EVPDAIPELTQ-RLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLL 119
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
LN+ N + + A GL ++ L L N ++ L G F + L L + N+ YL
Sbjct: 120 LLNLASNHLRELPQEALDGLGSLRRLELEGNALEGLRPGTFGALGALATLNLAHNALVYL 179
Query: 255 DSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNS-PLR 313
+ F+GL ++ +++S+N L + LPALR L L + ++ LP +S + L
Sbjct: 180 PAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLA 239
Query: 314 TLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L L N L L L L A+ L P FA L T + GN+L
Sbjct: 240 RLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQL 296
Score = 85.0 bits (201), Expect = 4e-16
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 1/201 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L+L + V+P AF G+ L L++ E+ + GAFRGL + +L+L N ++ LP
Sbjct: 73 LDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELP 132
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
L L + N+ L TF L + + +++N + L F L +R
Sbjct: 133 QEALDGLGSLRRLELEGNALEGLRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRW 192
Query: 292 LQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L+L +++ L E ++ P LR LSL N+L+ LP VL L L L +N +
Sbjct: 193 LRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAG 252
Query: 351 PELFADLRALETFVMDGNELQ 371
E L L ++DG LQ
Sbjct: 253 EEDGLALPGLRELLLDGGALQ 273
Score = 70.1 bits (164), Expect = 1e-11
Identities = 58/202 (28%), Positives = 88/202 (43%), Gaps = 2/202 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L+L +P AF GL L L++ IA + AGA GL + + L+ N++ L
Sbjct: 436 LDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYVYLSDNQLAGLS 495
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
A PRL L + RN F + R L + + + +N L ALR
Sbjct: 496 AAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRW 555
Query: 292 LQLDLSSIRELPEEFISNS-PLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
+ L + I E+ + + L L L RNQLR +P L G L L LS N + L
Sbjct: 556 VYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALR 615
Query: 351 PELFADL-RALETFVMDGNELQ 371
F + R+L+ ++ + L+
Sbjct: 616 DGAFQPVGRSLQHLFLNSSGLE 637
Score = 68.9 bits (161), Expect = 3e-11
Identities = 57/209 (27%), Positives = 83/209 (39%), Gaps = 1/209 (0%)
Query: 114 AFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLE 173
AF+GLG L+ + +P + L L L L L F L L
Sbjct: 111 AFRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALEGLRPGTFGALGALATLN 170
Query: 174 LSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAG 233
L+ + LP AF GL + L + N ++ + A GL + LSL+ N +QALP
Sbjct: 171 LAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGP 230
Query: 234 LFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQ 293
+ + L L + N Y E L ++E+ + L F++ P L TL
Sbjct: 231 VLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLD 290
Query: 294 LDLSSIRELPEEFISNSPLRTLSLARNQL 322
L + + LP LR L L N L
Sbjct: 291 LRGNQLDTLP-PLQGPGQLRRLRLQGNPL 318
Score = 66.5 bits (155), Expect = 2e-10
Identities = 58/217 (26%), Positives = 97/217 (44%), Gaps = 5/217 (2%)
Query: 114 AFKGLG-ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYL 172
AF GLG + +L + + G + L L +L + L+ + L A P L YL
Sbjct: 450 AFPGLGHLVSLHLQHCGI-AELEAGALAGLGRLIYVYLSDNQLAGLSAAALEGAPRLGYL 508
Query: 173 ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
L + +P A L L L++ +N + + G + + L+ NRI +
Sbjct: 509 YLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSL 568
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL-PALRT 291
G L L + RN R + + GL + E+++S N L++ F + +L+
Sbjct: 569 GALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQH 628
Query: 292 LQLDLSSIREL-PEEFISNSP-LRTLSLARNQLRVLP 326
L L+ S + ++ P F P L++L L +NQLR LP
Sbjct: 629 LFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALP 665
Score = 61.7 bits (143), Expect = 4e-09
Identities = 62/265 (23%), Positives = 98/265 (36%), Gaps = 5/265 (1%)
Query: 11 SVSACPEQCWCTDGEELNYQCSRPSTNLIVGARPRDYVNIDCMGGELVCAEFPEIDTPAT 70
+V+ CP C C E + C + P D +D P P
Sbjct: 398 AVAPCPRACVCVP-ESRHSSCEGCGLQAVPRGFPSDTQLLDLRRNHF--PSVPRAAFPGL 454
Query: 71 TQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGA 130
L SL L+ C + L + + N + L+A A +G +
Sbjct: 455 GHLVSLHLQHCGIAELEAGALAGLGRLIYVYLSDNQLAGLSAAALEGAPRLGYLYLERNR 514
Query: 131 QTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGL 190
VP LR+LP L L L T L+++ LS +IT + A
Sbjct: 515 FLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPA 574
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR-LLNLTMMRN 249
LE+L++ N++ + GA GL + L L+ N ++AL G F R L +L + +
Sbjct: 575 RELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSS 634
Query: 250 SFRYLDSETFRGL-DHIQEIKISNN 273
+ F GL +Q + + N
Sbjct: 635 GLEQICPGAFSGLGPGLQSLHLQKN 659
Score = 42.7 bits (96), Expect = 0.002
Identities = 39/169 (23%), Positives = 62/169 (36%), Gaps = 2/169 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
NA+ L F LG A + A +P + L ++ RL+ L A
Sbjct: 150 NALEGLRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALA 209
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
P L+ L L ++ LP L +L + N + L + L L+
Sbjct: 210 GLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDG 269
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
+QAL FA PRL L + N L +G ++ +++ N
Sbjct: 270 GALQALGPRAFAHCPRLHTLDLRGNQLDTL--PPLQGPGQLRRLRLQGN 316
Score = 35.9 bits (79), Expect = 0.25
Identities = 33/95 (34%), Positives = 45/95 (47%), Gaps = 5/95 (5%)
Query: 140 RSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLN-VLEQLNV 198
R L KL H N R + A P L L+LS + L D AF + L+ L +
Sbjct: 575 RELEKL-HLDRNQLREVPTGA--LEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFL 631
Query: 199 WENEIANITAGAFRGLH-NVTVLSLNKNRIQALPA 232
+ + I GAF GL + L L KN+++ALPA
Sbjct: 632 NSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALPA 666
Score = 34.3 bits (75), Expect = 0.76
Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 286 LPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
+P R + ++ +P F S++ L L L RN +PR+ G L SL L +
Sbjct: 409 VPESRHSSCEGCGLQAVPRGFPSDTQL--LDLRRNHFPSVPRAAFPGLGHLVSLHLQHCG 466
Query: 346 VAELAPELFADLRALETFVMDGNEL 370
+AEL A L L + N+L
Sbjct: 467 IAELEAGALAGLGRLIYVYLSDNQL 491
>BC068590-1|AAH68590.1| 778|Homo sapiens LOC150356 protein protein.
Length = 778
Score = 95.1 bits (226), Expect = 4e-19
Identities = 69/237 (29%), Positives = 110/237 (46%), Gaps = 4/237 (1%)
Query: 137 DVLRSLPKLTHFRLNAGRNI--TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLE 194
+V ++P+LT RL+ N+ + A F P L +L+L ++ ++ + AF GL L
Sbjct: 71 EVPDAIPELTQ-RLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLL 129
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
LN+ N + + A GL ++ L L N ++ L G F + L L + N+ YL
Sbjct: 130 LLNLASNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYL 189
Query: 255 DSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNS-PLR 313
+ F+GL ++ +++S+N L + LPALR L L + ++ LP +S + L
Sbjct: 190 PAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLA 249
Query: 314 TLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L L N L L L L A+ L P FA L T + GN+L
Sbjct: 250 RLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQL 306
Score = 85.4 bits (202), Expect = 3e-16
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 1/201 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L+L + V+P AF G+ L L++ E+ + GAFRGL + +L+L N ++ LP
Sbjct: 83 LDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELP 142
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
L L + N+ L TF L + + +++N + L F L +R
Sbjct: 143 QEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRW 202
Query: 292 LQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L+L +++ L E ++ P LR LSL N+L+ LP VL L L L +N +
Sbjct: 203 LRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAG 262
Query: 351 PELFADLRALETFVMDGNELQ 371
E L L ++DG LQ
Sbjct: 263 EEDGLALPGLRELLLDGGALQ 283
Score = 70.9 bits (166), Expect = 7e-12
Identities = 59/202 (29%), Positives = 88/202 (43%), Gaps = 2/202 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L+L +P AF GL L L++ IA + AGA GL + L L+ N++ L
Sbjct: 446 LDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLS 505
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
A PRL L + RN F + R L + + + +N L ALR
Sbjct: 506 AAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLHDNAVDRLAPGDLGRTRALRW 565
Query: 292 LQLDLSSIRELPEEFISNS-PLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
+ L + I E+ + + L L L RNQLR +P L G L L LS N + L
Sbjct: 566 VYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALR 625
Query: 351 PELFADL-RALETFVMDGNELQ 371
F + R+L+ ++ + L+
Sbjct: 626 DGAFQPVGRSLQHLFLNSSGLE 647
Score = 69.7 bits (163), Expect = 2e-11
Identities = 64/235 (27%), Positives = 105/235 (44%), Gaps = 7/235 (2%)
Query: 114 AFKGLG-ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYL 172
AF GLG + +L + + G + L L +L + L+ + L A P L YL
Sbjct: 460 AFPGLGHLVSLHLQHCGI-AELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYL 518
Query: 173 ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
L + +P A L L L++ +N + + G + + L+ NRI +
Sbjct: 519 YLERNRFLQVPGAALRALPSLFSLHLHDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSL 578
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLP-ALRT 291
G L L + RN R + + GL + E+++S N L++ F + +L+
Sbjct: 579 GALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQH 638
Query: 292 LQLDLSSIREL-PEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
L L+ S + ++ P F P L++L L +NQLR LP L +QL + LS N
Sbjct: 639 LFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALP--ALPSLSQLELIDLSSN 691
Score = 69.3 bits (162), Expect = 2e-11
Identities = 57/209 (27%), Positives = 83/209 (39%), Gaps = 1/209 (0%)
Query: 114 AFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLE 173
AF+GLG L+ + +P + L L L L L F L L
Sbjct: 121 AFRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLN 180
Query: 174 LSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAG 233
L+ + LP AF GL + L + N ++ + A GL + LSL+ N +QALP
Sbjct: 181 LAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGP 240
Query: 234 LFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQ 293
+ + L L + N Y E L ++E+ + L F++ P L TL
Sbjct: 241 VLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLD 300
Query: 294 LDLSSIRELPEEFISNSPLRTLSLARNQL 322
L + + LP LR L L N L
Sbjct: 301 LRGNQLDTLP-PLQGPGQLRRLRLQGNPL 328
Score = 60.9 bits (141), Expect = 8e-09
Identities = 71/291 (24%), Positives = 110/291 (37%), Gaps = 11/291 (3%)
Query: 11 SVSACPEQCWCTDGEELNYQCSRPSTNLIVGARPRDYVNIDCMGGELVCAEFPEIDTPAT 70
+V+ CP C C E + C + D +D P P
Sbjct: 408 AVAPCPRACVCVP-ESRHSSCEGCGLQAVPRGFRSDTQLLDLRRNHF--PSVPRAAFPGL 464
Query: 71 TQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGA 130
L SL L+ C + L + + N + L+A A +G +
Sbjct: 465 GHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNR 524
Query: 131 QTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGL 190
VP LR+LP L L+ L T L+++ LS +IT + A
Sbjct: 525 FLQVPGAALRALPSLFSLHLHDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPA 584
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR-LLNLTMMRN 249
LE+L++ N++ + GA GL + L L+ N ++AL G F R L +L + +
Sbjct: 585 RELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSS 644
Query: 250 SFRYLDSETFRGL-DHIQEIKISNNVPLTLKEAVFSNLPALRTLQL-DLSS 298
+ F GL +Q + + N L LP+L L+L DLSS
Sbjct: 645 GLEQICPGAFSGLGPGLQSLHLQKNQLRALPA-----LPSLSQLELIDLSS 690
Score = 43.2 bits (97), Expect = 0.002
Identities = 39/169 (23%), Positives = 62/169 (36%), Gaps = 2/169 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
NA+ L F LG A + A +P + L ++ RL+ L A
Sbjct: 160 NALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALA 219
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
P L+ L L ++ LP L +L + N + L + L L+
Sbjct: 220 GLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDG 279
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
+QAL FA PRL L + N L +G ++ +++ N
Sbjct: 280 GALQALGPRAFAHCPRLHTLDLRGNQLDTL--PPLQGPGQLRRLRLQGN 326
Score = 34.7 bits (76), Expect = 0.58
Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 286 LPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
+P R + ++ +P F S++ L L L RN +PR+ G L SL L +
Sbjct: 419 VPESRHSSCEGCGLQAVPRGFRSDTQL--LDLRRNHFPSVPRAAFPGLGHLVSLHLQHCG 476
Query: 346 VAELAPELFADLRALETFVMDGNEL 370
+AEL A L L + N+L
Sbjct: 477 IAELEAGALAGLGRLIYLYLSDNQL 501
>AL035681-1|CAI22653.1| 762|Homo sapiens protein ( Human DNA
sequence from clone RP4-756G23 on chromosome
22q13.31-13.33. ).
Length = 762
Score = 95.1 bits (226), Expect = 4e-19
Identities = 69/237 (29%), Positives = 110/237 (46%), Gaps = 4/237 (1%)
Query: 137 DVLRSLPKLTHFRLNAGRNI--TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLE 194
+V ++P+LT RL+ N+ + A F P L +L+L ++ ++ + AF GL L
Sbjct: 55 EVPDAIPELTQ-RLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLL 113
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
LN+ N + + A GL ++ L L N ++ L G F + L L + N+ YL
Sbjct: 114 LLNLASNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYL 173
Query: 255 DSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNS-PLR 313
+ F+GL ++ +++S+N L + LPALR L L + ++ LP +S + L
Sbjct: 174 PAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLA 233
Query: 314 TLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L L N L L L L A+ L P FA L T + GN+L
Sbjct: 234 RLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQL 290
Score = 85.4 bits (202), Expect = 3e-16
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 1/201 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L+L + V+P AF G+ L L++ E+ + GAFRGL + +L+L N ++ LP
Sbjct: 67 LDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELP 126
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
L L + N+ L TF L + + +++N + L F L +R
Sbjct: 127 QEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRW 186
Query: 292 LQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L+L +++ L E ++ P LR LSL N+L+ LP VL L L L +N +
Sbjct: 187 LRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAG 246
Query: 351 PELFADLRALETFVMDGNELQ 371
E L L ++DG LQ
Sbjct: 247 EEDGLALPGLRELLLDGGALQ 267
Score = 71.3 bits (167), Expect = 5e-12
Identities = 59/202 (29%), Positives = 88/202 (43%), Gaps = 2/202 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L+L +P AF GL L L++ IA + AGA GL + L L+ N++ L
Sbjct: 430 LDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLS 489
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
A PRL L + RN F + R L + + + +N L ALR
Sbjct: 490 AAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRW 549
Query: 292 LQLDLSSIRELPEEFISNS-PLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
+ L + I E+ + + L L L RNQLR +P L G L L LS N + L
Sbjct: 550 VYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALR 609
Query: 351 PELFADL-RALETFVMDGNELQ 371
F + R+L+ ++ + L+
Sbjct: 610 DGAFQPVGRSLQHLFLNSSGLE 631
Score = 69.7 bits (163), Expect = 2e-11
Identities = 64/235 (27%), Positives = 105/235 (44%), Gaps = 7/235 (2%)
Query: 114 AFKGLG-ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYL 172
AF GLG + +L + + G + L L +L + L+ + L A P L YL
Sbjct: 444 AFPGLGHLVSLHLQHCGI-AELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYL 502
Query: 173 ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
L + +P A L L L++ +N + + G + + L+ NRI +
Sbjct: 503 YLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSL 562
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLP-ALRT 291
G L L + RN R + + GL + E+++S N L++ F + +L+
Sbjct: 563 GALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQH 622
Query: 292 LQLDLSSIREL-PEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
L L+ S + ++ P F P L++L L +NQLR LP L +QL + LS N
Sbjct: 623 LFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALP--ALPSLSQLELIDLSSN 675
Score = 69.3 bits (162), Expect = 2e-11
Identities = 57/209 (27%), Positives = 83/209 (39%), Gaps = 1/209 (0%)
Query: 114 AFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLE 173
AF+GLG L+ + +P + L L L L L F L L
Sbjct: 105 AFRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLN 164
Query: 174 LSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAG 233
L+ + LP AF GL + L + N ++ + A GL + LSL+ N +QALP
Sbjct: 165 LAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGP 224
Query: 234 LFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQ 293
+ + L L + N Y E L ++E+ + L F++ P L TL
Sbjct: 225 VLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLD 284
Query: 294 LDLSSIRELPEEFISNSPLRTLSLARNQL 322
L + + LP LR L L N L
Sbjct: 285 LRGNQLDTLP-PLQGPGQLRRLRLQGNPL 312
Score = 64.1 bits (149), Expect = 8e-10
Identities = 72/291 (24%), Positives = 110/291 (37%), Gaps = 11/291 (3%)
Query: 11 SVSACPEQCWCTDGEELNYQCSRPSTNLIVGARPRDYVNIDCMGGELVCAEFPEIDTPAT 70
+V+ CP C C E + C + P D +D P P
Sbjct: 392 AVAPCPRACVCVP-ESRHSSCEGCGLQAVPRGFPSDTQLLDLRRNHF--PSVPRAAFPGL 448
Query: 71 TQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGA 130
L SL L+ C + L + + N + L+A A +G +
Sbjct: 449 GHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNR 508
Query: 131 QTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGL 190
VP LR+LP L L L T L+++ LS +IT + A
Sbjct: 509 FLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPA 568
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR-LLNLTMMRN 249
LE+L++ N++ + GA GL + L L+ N ++AL G F R L +L + +
Sbjct: 569 RELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSS 628
Query: 250 SFRYLDSETFRGL-DHIQEIKISNNVPLTLKEAVFSNLPALRTLQL-DLSS 298
+ F GL +Q + + N L LP+L L+L DLSS
Sbjct: 629 GLEQICPGAFSGLGPGLQSLHLQKNQLRALPA-----LPSLSQLELIDLSS 674
Score = 43.2 bits (97), Expect = 0.002
Identities = 39/169 (23%), Positives = 62/169 (36%), Gaps = 2/169 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
NA+ L F LG A + A +P + L ++ RL+ L A
Sbjct: 144 NALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALA 203
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
P L+ L L ++ LP L +L + N + L + L L+
Sbjct: 204 GLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDG 263
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
+QAL FA PRL L + N L +G ++ +++ N
Sbjct: 264 GALQALGPRAFAHCPRLHTLDLRGNQLDTL--PPLQGPGQLRRLRLQGN 310
Score = 34.7 bits (76), Expect = 0.58
Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 286 LPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
+P R + ++ +P F S++ L L L RN +PR+ G L SL L +
Sbjct: 403 VPESRHSSCEGCGLQAVPRGFPSDTQL--LDLRRNHFPSVPRAAFPGLGHLVSLHLQHCG 460
Query: 346 VAELAPELFADLRALETFVMDGNEL 370
+AEL A L L + N+L
Sbjct: 461 IAELEAGALAGLGRLIYLYLSDNQL 485
>AF257182-1|AAF68989.1| 951|Homo sapiens G-protein-coupled receptor
48 protein.
Length = 951
Score = 93.5 bits (222), Expect = 1e-18
Identities = 69/266 (25%), Positives = 122/266 (45%), Gaps = 3/266 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + + ++A +GL + +A T+VP D L +L H L+ + + +
Sbjct: 115 NQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLS 174
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N P L+ L L+ KI+ +PD AF L+ L L++ N+I ++ F GL N+ L L+
Sbjct: 175 NLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSY 234
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N + P + A P L L NS + F G ++ I + +N + +
Sbjct: 235 NNLGEFPQAIKA-RPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSASH 293
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
NL L +L + +S+ + L +L+L ++ +P ++ + Q L +L LSYN
Sbjct: 294 NLSDLHSLVIRGASMVQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYN 353
Query: 345 AVAELAPELFADLRALETFVMDGNEL 370
+ +L F ALE + N++
Sbjct: 354 NIRDLPS--FNGCHALEEISLQRNQI 377
Score = 92.7 bits (220), Expect = 2e-18
Identities = 65/267 (24%), Positives = 121/267 (45%), Gaps = 9/267 (3%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGL 190
T +P D ++ P L +L AG +++ +H + LK L L + ++ +P +A GL
Sbjct: 70 TQLPEDAFKNFPFLEELQL-AGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGL 128
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS 250
+ L+ L + N I ++ +F GL + L L+ N + +P ++ P L LT+ N
Sbjct: 129 SALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNK 188
Query: 251 FRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNS 310
+ F L + + + NN L + F L L TL L +++ E P+ +
Sbjct: 189 ISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFPQAIKARP 248
Query: 311 PLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L+ L N + V+P G L ++ L N ++ + +L L + V+ G +
Sbjct: 249 SLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSASHNLSDLHSLVIRGASM 308
Query: 371 ------QVGYVYIDDILVAGHTRVSMI 391
G V+++ + + G T++S I
Sbjct: 309 VQQFPNLTGTVHLESLTLTG-TKISSI 334
Score = 89.4 bits (212), Expect = 2e-17
Identities = 59/202 (29%), Positives = 99/202 (49%), Gaps = 2/202 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L++S IT LP+DAF LE+L + N+++ I A GL + VL+L N+++ +P
Sbjct: 62 LDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVP 121
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
+ L +L + N + ++F GL ++ + + +N + SNLP L+
Sbjct: 122 SEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQA 181
Query: 292 LQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L L L+ I +P+ F + S L L L N++R L + G L +L LSYN + E
Sbjct: 182 LTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEF- 240
Query: 351 PELFADLRALETFVMDGNELQV 372
P+ +L+ N + V
Sbjct: 241 PQAIKARPSLKELGFHSNSISV 262
Score = 83.8 bits (198), Expect = 9e-16
Identities = 71/292 (24%), Positives = 125/292 (42%), Gaps = 3/292 (1%)
Query: 80 ECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVL 139
+CS L+ + + + A + N I L DAFK + + + L
Sbjct: 42 DCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKAL 101
Query: 140 RSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
L +L L + T+ + L+ L L IT +P+D+F GL L L +
Sbjct: 102 SGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLD 161
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
+N + + L + L+L N+I ++P F + L+ L + N R L F
Sbjct: 162 DNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCF 221
Query: 260 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLA 318
GLD+++ + +S N +A+ + P+L+ L +SI +P+ F N LRT+ L
Sbjct: 222 DGLDNLETLDLSYNNLGEFPQAIKAR-PSLKELGFHSNSISVIPDGAFDGNPLLRTIHLY 280
Query: 319 RNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
N L + S + L SL + ++ + P L + LE+ + G ++
Sbjct: 281 DNPLSFVGNSASHNLSDLHSLVIRGASMVQQFPNLTGTVH-LESLTLTGTKI 331
Score = 62.9 bits (146), Expect = 2e-09
Identities = 69/301 (22%), Positives = 118/301 (39%), Gaps = 9/301 (2%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVF---KNAINPLNADAFKGLGI 120
E+ + LP+L +L +S + VV N I L+ F GL
Sbjct: 167 EVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDN 226
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
+ + P +++ P L ++ + F P L+ + L D ++
Sbjct: 227 LETLDLSYNNLGEFP-QAIKARPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLS 285
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
+ + A L+ L L + + +H + L+L +I ++P L
Sbjct: 286 FVGNSASHNLSDLHSLVIRGASMVQQFPNLTGTVH-LESLTLTGTKISSIPNNLCQEQKM 344
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIR 300
L L + N+ R L S F G ++EI + N +KE F L +LR L L + I
Sbjct: 345 LRTLDLSYNNIRDLPS--FNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIH 402
Query: 301 EL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRA 359
E+ F + P+ L ++ N+L P G QL L ++ LA + F +LR+
Sbjct: 403 EIHSRAFATLGPITNLDVSFNELTSFPTEGPNGLNQL-KLVGNFKLKEALAAKDFVNLRS 461
Query: 360 L 360
L
Sbjct: 462 L 462
>BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein.
Length = 673
Score = 93.1 bits (221), Expect = 2e-18
Identities = 85/244 (34%), Positives = 115/244 (47%), Gaps = 14/244 (5%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGL 190
TTVP DV L F IT L A FA P L+ L+LS +I LP F L
Sbjct: 44 TTVPRDVPPDTVGLYVFE----NGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPL 99
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS 250
L L++ N + IT FRGL + L L KNRI+ + G F + RLL L + N
Sbjct: 100 ANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNE 159
Query: 251 FRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF--SNLPALRTLQLDLSSIRELPEEFIS 308
R L L + + +S+N L L+ + +N+ ALR L L + E +
Sbjct: 160 LRALPP---LRLPRLLLLDLSHNSLLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLR 216
Query: 309 NSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA-VAELAPELFADLRALETFVMDG 367
N L L ++ NQL +P V+RG LT L L+ N +A+L PE A L AL+ +
Sbjct: 217 N--LHDLDVSDNQLERVP-PVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSN 273
Query: 368 NELQ 371
LQ
Sbjct: 274 LSLQ 277
Score = 83.4 bits (197), Expect = 1e-15
Identities = 59/202 (29%), Positives = 101/202 (50%), Gaps = 9/202 (4%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L V+EN I + AG+F GL + +L L++N+I +LP+G+F L NL + N +
Sbjct: 57 LYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEIT 116
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
+ETFRGL ++ + + N ++ F L L L+L + +R LP + L L
Sbjct: 117 NETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPP--LRLPRLLLL 174
Query: 316 SLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ---- 371
L+ N L L +L + +L L+ + +L LF+ LR L + N+L+
Sbjct: 175 DLSHNSLLALEPGIL-DTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPP 233
Query: 372 --VGYVYIDDILVAGHTRVSMI 391
G + + +AG+TR++ +
Sbjct: 234 VIRGLRGLTRLRLAGNTRIAQL 255
Score = 59.3 bits (137), Expect = 2e-08
Identities = 76/272 (27%), Positives = 114/272 (41%), Gaps = 32/272 (11%)
Query: 93 VHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNA 152
V + V VF+N I L+A +F GL L+ + ++P V + L L++ L A
Sbjct: 50 VPPDTVGLYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTA 109
Query: 153 GRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR 212
R LH +IT ++ F GL LE+L + +N I +I GAF
Sbjct: 110 NR---LH------------------EIT---NETFRGLRRLERLYLGKNRIRHIQPGAFD 145
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISN 272
L + L L N ++ALP PRLL L + NS L+ +++ ++++
Sbjct: 146 TLDRLLELKLQDNELRALPP---LRLPRLLLLDLSHNSLLALEPGIL-DTANVEALRLAG 201
Query: 273 NVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARN----QLRVLPRS 328
L E +FS L L L + + + +P L L LA N QLR +
Sbjct: 202 LGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLAGNTRIAQLRPEDLA 261
Query: 329 VLRGQTQLTSLTLSYNAVAELAPELFADLRAL 360
L +L LS A+ LF LR L
Sbjct: 262 GLAALQELDVSNLSLQALPGDLSGLFPRLRLL 293
Score = 35.1 bits (77), Expect = 0.44
Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 2/95 (2%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN-EIANITAGAFRGLHN 216
L +F+ L L++SD ++ +P GL L +L + N IA + GL
Sbjct: 207 LDEGLFSRLRNLHDLDVSDNQLERVPP-VIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAA 265
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
+ L ++ +QALP L PRL L RN F
Sbjct: 266 LQELDVSNLSLQALPGDLSGLFPRLRLLAAARNPF 300
>AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein.
Length = 673
Score = 93.1 bits (221), Expect = 2e-18
Identities = 85/244 (34%), Positives = 115/244 (47%), Gaps = 14/244 (5%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGL 190
TTVP DV L F IT L A FA P L+ L+LS +I LP F L
Sbjct: 44 TTVPRDVPPDTVGLYVFE----NGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPL 99
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS 250
L L++ N + IT FRGL + L L KNRI+ + G F + RLL L + N
Sbjct: 100 ANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNE 159
Query: 251 FRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF--SNLPALRTLQLDLSSIRELPEEFIS 308
R L L + + +S+N L L+ + +N+ ALR L L + E +
Sbjct: 160 LRALPP---LRLPRLLLLDLSHNSLLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLR 216
Query: 309 NSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA-VAELAPELFADLRALETFVMDG 367
N L L ++ NQL +P V+RG LT L L+ N +A+L PE A L AL+ +
Sbjct: 217 N--LHDLDVSDNQLERVP-PVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSN 273
Query: 368 NELQ 371
LQ
Sbjct: 274 LSLQ 277
Score = 83.4 bits (197), Expect = 1e-15
Identities = 59/202 (29%), Positives = 101/202 (50%), Gaps = 9/202 (4%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L V+EN I + AG+F GL + +L L++N+I +LP+G+F L NL + N +
Sbjct: 57 LYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEIT 116
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
+ETFRGL ++ + + N ++ F L L L+L + +R LP + L L
Sbjct: 117 NETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPP--LRLPRLLLL 174
Query: 316 SLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ---- 371
L+ N L L +L + +L L+ + +L LF+ LR L + N+L+
Sbjct: 175 DLSHNSLLALEPGIL-DTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPP 233
Query: 372 --VGYVYIDDILVAGHTRVSMI 391
G + + +AG+TR++ +
Sbjct: 234 VIRGLRGLTRLRLAGNTRIAQL 255
Score = 59.3 bits (137), Expect = 2e-08
Identities = 76/272 (27%), Positives = 114/272 (41%), Gaps = 32/272 (11%)
Query: 93 VHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNA 152
V + V VF+N I L+A +F GL L+ + ++P V + L L++ L A
Sbjct: 50 VPPDTVGLYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTA 109
Query: 153 GRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR 212
R LH +IT ++ F GL LE+L + +N I +I GAF
Sbjct: 110 NR---LH------------------EIT---NETFRGLRRLERLYLGKNRIRHIQPGAFD 145
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISN 272
L + L L N ++ALP PRLL L + NS L+ +++ ++++
Sbjct: 146 TLDRLLELKLQDNELRALPP---LRLPRLLLLDLSHNSLLALEPGIL-DTANVEALRLAG 201
Query: 273 NVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARN----QLRVLPRS 328
L E +FS L L L + + + +P L L LA N QLR +
Sbjct: 202 LGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLAGNTRIAQLRPEDLA 261
Query: 329 VLRGQTQLTSLTLSYNAVAELAPELFADLRAL 360
L +L LS A+ LF LR L
Sbjct: 262 GLAALQELDVSNLSLQALPGDLSGLFPRLRLL 293
Score = 35.1 bits (77), Expect = 0.44
Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 2/95 (2%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN-EIANITAGAFRGLHN 216
L +F+ L L++SD ++ +P GL L +L + N IA + GL
Sbjct: 207 LDEGLFSRLRNLHDLDVSDNQLERVPP-VIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAA 265
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
+ L ++ +QALP L PRL L RN F
Sbjct: 266 LQELDVSNLSLQALPGDLSGLFPRLRLLAAARNPF 300
>AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein.
Length = 673
Score = 93.1 bits (221), Expect = 2e-18
Identities = 85/244 (34%), Positives = 115/244 (47%), Gaps = 14/244 (5%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGL 190
TTVP DV L F IT L A FA P L+ L+LS +I LP F L
Sbjct: 44 TTVPRDVPPDTVGLYVFE----NGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPL 99
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS 250
L L++ N + IT FRGL + L L KNRI+ + G F + RLL L + N
Sbjct: 100 ANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNE 159
Query: 251 FRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF--SNLPALRTLQLDLSSIRELPEEFIS 308
R L L + + +S+N L L+ + +N+ ALR L L + E +
Sbjct: 160 LRALPP---LRLPRLLLLDLSHNSLLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLR 216
Query: 309 NSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA-VAELAPELFADLRALETFVMDG 367
N L L ++ NQL +P V+RG LT L L+ N +A+L PE A L AL+ +
Sbjct: 217 N--LHDLDVSDNQLERVP-PVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSN 273
Query: 368 NELQ 371
LQ
Sbjct: 274 LSLQ 277
Score = 83.4 bits (197), Expect = 1e-15
Identities = 59/202 (29%), Positives = 101/202 (50%), Gaps = 9/202 (4%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L V+EN I + AG+F GL + +L L++N+I +LP+G+F L NL + N +
Sbjct: 57 LYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEIT 116
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
+ETFRGL ++ + + N ++ F L L L+L + +R LP + L L
Sbjct: 117 NETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPP--LRLPRLLLL 174
Query: 316 SLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ---- 371
L+ N L L +L + +L L+ + +L LF+ LR L + N+L+
Sbjct: 175 DLSHNSLLALEPGIL-DTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPP 233
Query: 372 --VGYVYIDDILVAGHTRVSMI 391
G + + +AG+TR++ +
Sbjct: 234 VIRGLRGLTRLRLAGNTRIAQL 255
Score = 59.3 bits (137), Expect = 2e-08
Identities = 76/272 (27%), Positives = 114/272 (41%), Gaps = 32/272 (11%)
Query: 93 VHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNA 152
V + V VF+N I L+A +F GL L+ + ++P V + L L++ L A
Sbjct: 50 VPPDTVGLYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTA 109
Query: 153 GRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR 212
R LH +IT ++ F GL LE+L + +N I +I GAF
Sbjct: 110 NR---LH------------------EIT---NETFRGLRRLERLYLGKNRIRHIQPGAFD 145
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISN 272
L + L L N ++ALP PRLL L + NS L+ +++ ++++
Sbjct: 146 TLDRLLELKLQDNELRALPP---LRLPRLLLLDLSHNSLLALEPGIL-DTANVEALRLAG 201
Query: 273 NVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARN----QLRVLPRS 328
L E +FS L L L + + + +P L L LA N QLR +
Sbjct: 202 LGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLAGNTRIAQLRPEDLA 261
Query: 329 VLRGQTQLTSLTLSYNAVAELAPELFADLRAL 360
L +L LS A+ LF LR L
Sbjct: 262 GLAALQELDVSNLSLQALPGDLSGLFPRLRLL 293
Score = 35.1 bits (77), Expect = 0.44
Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 2/95 (2%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN-EIANITAGAFRGLHN 216
L +F+ L L++SD ++ +P GL L +L + N IA + GL
Sbjct: 207 LDEGLFSRLRNLHDLDVSDNQLERVPP-VIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAA 265
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
+ L ++ +QALP L PRL L RN F
Sbjct: 266 LQELDVSNLSLQALPGDLSGLFPRLRLLAAARNPF 300
>BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 91.9 bits (218), Expect = 4e-18
Identities = 68/262 (25%), Positives = 114/262 (43%), Gaps = 6/262 (2%)
Query: 105 NAINPLNADAFKGLGITALMM-FNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N I L A F L + L++ N + +P + + LP L L R + F
Sbjct: 177 NRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPHLQFLELKRNRIKIVEGLTF 235
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
L+ L++ I+ L D AF GLN +E+L + N + + G GL + L ++
Sbjct: 236 QGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVS 295
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
+N I+ + + RL L + N LD F GL ++ + + +N + + VF
Sbjct: 296 QNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVF 355
Query: 284 SNLPALRTLQL---DLS-SIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSL 339
L L+TL L ++S +I + E F + L L L NQ++ + + G L L
Sbjct: 356 RFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHL 415
Query: 340 TLSYNAVAELAPELFADLRALE 361
L+ NA+ + F+ E
Sbjct: 416 DLNNNAIMSIQENAFSQTHLKE 437
Score = 77.4 bits (182), Expect = 8e-14
Identities = 68/230 (29%), Positives = 108/230 (46%), Gaps = 28/230 (12%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHN-VTVLSLNKN 225
P L+ L+LS I+ + +F + L+ LN+ N I + AG F L + + V+ LN+N
Sbjct: 144 PALESLDLSSNIISEIKTSSFPRMQ-LKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRN 202
Query: 226 RIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSN 285
R+ +P +F P L L + RN + ++ TF+GLD ++ +K+ N LK+ F
Sbjct: 203 RMSMIPPKIF-KLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFG 261
Query: 286 LPALRTLQLD-----------LSSIRELPEEFISN------SP--------LRTLSLARN 320
L + L+L+ L +R L + ++S SP L L L+ N
Sbjct: 262 LNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYN 321
Query: 321 QLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
QL L S G + L L L N V +A +F L L+T + NE+
Sbjct: 322 QLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEI 371
Score = 59.3 bits (137), Expect = 2e-08
Identities = 40/156 (25%), Positives = 76/156 (48%), Gaps = 2/156 (1%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N+T+LSL N I + A P L +L + N + + +F + ++ + +SNN
Sbjct: 121 NITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRM-QLKYLNLSNNRI 179
Query: 276 LTLKEAVFSNL-PALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQT 334
TL+ F NL +L ++L+ + + +P + L+ L L RN+++++ +G
Sbjct: 180 TTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLD 239
Query: 335 QLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L SL + N +++L F L +E ++ N L
Sbjct: 240 SLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNL 275
>BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 91.9 bits (218), Expect = 4e-18
Identities = 68/262 (25%), Positives = 114/262 (43%), Gaps = 6/262 (2%)
Query: 105 NAINPLNADAFKGLGITALMM-FNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N I L A F L + L++ N + +P + + LP L L R + F
Sbjct: 177 NRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPHLQFLELKRNRIKIVEGLTF 235
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
L+ L++ I+ L D AF GLN +E+L + N + + G GL + L ++
Sbjct: 236 QGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVS 295
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
+N I+ + + RL L + N LD F GL ++ + + +N + + VF
Sbjct: 296 QNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVF 355
Query: 284 SNLPALRTLQL---DLS-SIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSL 339
L L+TL L ++S +I + E F + L L L NQ++ + + G L L
Sbjct: 356 RFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHL 415
Query: 340 TLSYNAVAELAPELFADLRALE 361
L+ NA+ + F+ E
Sbjct: 416 DLNNNAIMSIQENAFSQTHLKE 437
Score = 77.4 bits (182), Expect = 8e-14
Identities = 68/230 (29%), Positives = 108/230 (46%), Gaps = 28/230 (12%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHN-VTVLSLNKN 225
P L+ L+LS I+ + +F + L+ LN+ N I + AG F L + + V+ LN+N
Sbjct: 144 PALESLDLSSNIISEIKTSSFPRMQ-LKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRN 202
Query: 226 RIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSN 285
R+ +P +F P L L + RN + ++ TF+GLD ++ +K+ N LK+ F
Sbjct: 203 RMSMIPPKIF-KLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFG 261
Query: 286 LPALRTLQLD-----------LSSIRELPEEFISN------SP--------LRTLSLARN 320
L + L+L+ L +R L + ++S SP L L L+ N
Sbjct: 262 LNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYN 321
Query: 321 QLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
QL L S G + L L L N V +A +F L L+T + NE+
Sbjct: 322 QLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEI 371
Score = 59.3 bits (137), Expect = 2e-08
Identities = 40/156 (25%), Positives = 76/156 (48%), Gaps = 2/156 (1%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N+T+LSL N I + A P L +L + N + + +F + ++ + +SNN
Sbjct: 121 NITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRM-QLKYLNLSNNRI 179
Query: 276 LTLKEAVFSNL-PALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQT 334
TL+ F NL +L ++L+ + + +P + L+ L L RN+++++ +G
Sbjct: 180 TTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLD 239
Query: 335 QLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L SL + N +++L F L +E ++ N L
Sbjct: 240 SLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNL 275
>AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 91.9 bits (218), Expect = 4e-18
Identities = 68/262 (25%), Positives = 114/262 (43%), Gaps = 6/262 (2%)
Query: 105 NAINPLNADAFKGLGITALMM-FNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N I L A F L + L++ N + +P + + LP L L R + F
Sbjct: 177 NRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPHLQFLELKRNRIKIVEGLTF 235
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
L+ L++ I+ L D AF GLN +E+L + N + + G GL + L ++
Sbjct: 236 QGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVS 295
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
+N I+ + + RL L + N LD F GL ++ + + +N + + VF
Sbjct: 296 QNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVF 355
Query: 284 SNLPALRTLQL---DLS-SIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSL 339
L L+TL L ++S +I + E F + L L L NQ++ + + G L L
Sbjct: 356 RFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHL 415
Query: 340 TLSYNAVAELAPELFADLRALE 361
L+ NA+ + F+ E
Sbjct: 416 DLNNNAIMSIQENAFSQTHLKE 437
Score = 77.4 bits (182), Expect = 8e-14
Identities = 68/230 (29%), Positives = 108/230 (46%), Gaps = 28/230 (12%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHN-VTVLSLNKN 225
P L+ L+LS I+ + +F + L+ LN+ N I + AG F L + + V+ LN+N
Sbjct: 144 PALESLDLSSNIISEIKTSSFPRMQ-LKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRN 202
Query: 226 RIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSN 285
R+ +P +F P L L + RN + ++ TF+GLD ++ +K+ N LK+ F
Sbjct: 203 RMSMIPPKIF-KLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFG 261
Query: 286 LPALRTLQLD-----------LSSIRELPEEFISN------SP--------LRTLSLARN 320
L + L+L+ L +R L + ++S SP L L L+ N
Sbjct: 262 LNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYN 321
Query: 321 QLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
QL L S G + L L L N V +A +F L L+T + NE+
Sbjct: 322 QLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEI 371
Score = 59.3 bits (137), Expect = 2e-08
Identities = 40/156 (25%), Positives = 76/156 (48%), Gaps = 2/156 (1%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N+T+LSL N I + A P L +L + N + + +F + ++ + +SNN
Sbjct: 121 NITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRM-QLKYLNLSNNRI 179
Query: 276 LTLKEAVFSNL-PALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQT 334
TL+ F NL +L ++L+ + + +P + L+ L L RN+++++ +G
Sbjct: 180 TTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLD 239
Query: 335 QLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L SL + N +++L F L +E ++ N L
Sbjct: 240 SLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNL 275
>AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein.
Length = 1073
Score = 91.9 bits (218), Expect = 4e-18
Identities = 68/262 (25%), Positives = 114/262 (43%), Gaps = 6/262 (2%)
Query: 105 NAINPLNADAFKGLGITALMM-FNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N I L A F L + L++ N + +P + + LP L L R + F
Sbjct: 185 NRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPHLQFLELKRNRIKIVEGLTF 243
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
L+ L++ I+ L D AF GLN +E+L + N + + G GL + L ++
Sbjct: 244 QGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVS 303
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
+N I+ + + RL L + N LD F GL ++ + + +N + + VF
Sbjct: 304 QNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVF 363
Query: 284 SNLPALRTLQL---DLS-SIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSL 339
L L+TL L ++S +I + E F + L L L NQ++ + + G L L
Sbjct: 364 RFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHL 423
Query: 340 TLSYNAVAELAPELFADLRALE 361
L+ NA+ + F+ E
Sbjct: 424 DLNNNAIMSIQENAFSQTHLKE 445
Score = 77.4 bits (182), Expect = 8e-14
Identities = 68/230 (29%), Positives = 108/230 (46%), Gaps = 28/230 (12%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHN-VTVLSLNKN 225
P L+ L+LS I+ + +F + L+ LN+ N I + AG F L + + V+ LN+N
Sbjct: 152 PALESLDLSSNIISEIKTSSFPRMQ-LKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRN 210
Query: 226 RIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSN 285
R+ +P +F P L L + RN + ++ TF+GLD ++ +K+ N LK+ F
Sbjct: 211 RMSMIPPKIF-KLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFG 269
Query: 286 LPALRTLQLD-----------LSSIRELPEEFISN------SP--------LRTLSLARN 320
L + L+L+ L +R L + ++S SP L L L+ N
Sbjct: 270 LNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYN 329
Query: 321 QLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
QL L S G + L L L N V +A +F L L+T + NE+
Sbjct: 330 QLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEI 379
Score = 59.3 bits (137), Expect = 2e-08
Identities = 40/156 (25%), Positives = 76/156 (48%), Gaps = 2/156 (1%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N+T+LSL N I + A P L +L + N + + +F + ++ + +SNN
Sbjct: 129 NITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRM-QLKYLNLSNNRI 187
Query: 276 LTLKEAVFSNL-PALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQT 334
TL+ F NL +L ++L+ + + +P + L+ L L RN+++++ +G
Sbjct: 188 TTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLD 247
Query: 335 QLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L SL + N +++L F L +E ++ N L
Sbjct: 248 SLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNL 283
>AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein
LRIG1 protein.
Length = 1093
Score = 89.8 bits (213), Expect = 1e-17
Identities = 80/328 (24%), Positives = 143/328 (43%), Gaps = 10/328 (3%)
Query: 40 VGARPRDYVNIDCMGGELVCAEFPEIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVK 99
+GA V++ ++ E ++ + ++ LSL + +C H +K
Sbjct: 110 LGAASSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCF---PHGPPIK 166
Query: 100 TV-VFKNAINPLNADAFKGLGITALMM-FNAGAQTTVPVDVLRSLPKLTHFRLNAGRNIT 157
+ + N I L AF GL + L + + T +PV + LP+LT LN R
Sbjct: 167 ELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRL 225
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
+ F L+ L+L I+ L D AF GL+ + L++ N + + +G+ GL +
Sbjct: 226 IEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTAL 285
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
L L+ N I + ++ +L L + N+ LD E+ L + +++S+N
Sbjct: 286 HQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISH 345
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPEE----FISNSPLRTLSLARNQLRVLPRSVLRGQ 333
+ E F L +LR L LD + I E+ F L L+L N+++ + + G
Sbjct: 346 IAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGL 405
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALE 361
L L L NA+ + + F ++ L+
Sbjct: 406 EGLEHLNLGGNAIRSVQFDAFVKMKNLK 433
Score = 81.0 bits (191), Expect = 7e-15
Identities = 68/219 (31%), Positives = 102/219 (46%), Gaps = 4/219 (1%)
Query: 155 NITLHANM-FANTPPLKYLELSDAKITVLPDDAFLGLN-VLEQLNVWENEIANITAGAFR 212
NIT N F + PP+K L L+ +I L AF GL+ L L + +N I + AF+
Sbjct: 150 NITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFK 209
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISN 272
L +T L LN+NRI+ + F L L + RN+ L F GL + + +
Sbjct: 210 -LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEY 268
Query: 273 NVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLR 331
N + + L AL L L +SI + + S L L L+ N L L L
Sbjct: 269 NSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLA 328
Query: 332 GQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ L+ L LS+N+++ +A F LR+L +D NE+
Sbjct: 329 ELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEI 367
Score = 66.9 bits (156), Expect = 1e-10
Identities = 49/198 (24%), Positives = 86/198 (43%), Gaps = 3/198 (1%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
+N I+ L AF GL ++ + V L L L L+ +H +
Sbjct: 244 RNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGW 303
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
+ L L LS +T L +++ L+ L L + N I++I GAF+GL ++ VL L+
Sbjct: 304 SFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLD 363
Query: 224 KNRIQAL---PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKE 280
N I +G F+ L LT+ N + + F GL+ ++ + + N +++
Sbjct: 364 HNEISGTIEDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQF 423
Query: 281 AVFSNLPALRTLQLDLSS 298
F + L+ L + S
Sbjct: 424 DAFVKMKNLKELHISSDS 441
Score = 54.0 bits (124), Expect = 9e-07
Identities = 49/200 (24%), Positives = 89/200 (44%), Gaps = 2/200 (1%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L LS K++ + F L L+++ + NE+ + + H V+ L L N+I+++
Sbjct: 73 LNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVS-LFLQHNKIRSVE 131
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLP-ALR 290
+ L L + N+ + + F I+E+ ++ N TL+ F L +L
Sbjct: 132 GSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLL 191
Query: 291 TLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
TL+L + I +LP L L L RN++R++ +G L L L N +++L
Sbjct: 192 TLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLT 251
Query: 351 PELFADLRALETFVMDGNEL 370
F L + ++ N L
Sbjct: 252 DGAFWGLSKMHVLHLEYNSL 271
Score = 43.6 bits (98), Expect = 0.001
Identities = 33/123 (26%), Positives = 57/123 (46%), Gaps = 3/123 (2%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDD---AFL 188
T + + L L L+ RL+ + F L+ L+L +I+ +D AF
Sbjct: 320 TRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFS 379
Query: 189 GLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMR 248
GL+ L +L ++ N+I ++ AF GL + L+L N I+++ F L L +
Sbjct: 380 GLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHISS 439
Query: 249 NSF 251
+SF
Sbjct: 440 DSF 442
Score = 31.9 bits (69), Expect = 4.1
Identities = 15/33 (45%), Positives = 21/33 (63%)
Query: 338 SLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
SL LSYN ++E+ P F DL L+ ++ NEL
Sbjct: 72 SLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNEL 104
Score = 31.5 bits (68), Expect = 5.4
Identities = 37/146 (25%), Positives = 64/146 (43%), Gaps = 6/146 (4%)
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
+ ALP L S R LNL+ N +D F L ++QE+ ++NN LT ++ +
Sbjct: 59 LAALPGDL-PSWTRSLNLSY--NKLSEIDPAGFEDLPNLQEVYLNNN-ELTAVPSLGAAS 114
Query: 287 PALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
+ +L L + IR + + + L L L+ N + + + + L L+ N
Sbjct: 115 SHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNR 174
Query: 346 VAELAPELFADL-RALETFVMDGNEL 370
+ L F L R+L T + N +
Sbjct: 175 IGTLELGAFDGLSRSLLTLRLSKNRI 200
>AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein
LIG-1 protein.
Length = 1094
Score = 89.8 bits (213), Expect = 1e-17
Identities = 80/328 (24%), Positives = 143/328 (43%), Gaps = 10/328 (3%)
Query: 40 VGARPRDYVNIDCMGGELVCAEFPEIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVK 99
+GA V++ ++ E ++ + ++ LSL + +C H +K
Sbjct: 110 LGAASSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCF---PHGPPIK 166
Query: 100 TV-VFKNAINPLNADAFKGLGITALMM-FNAGAQTTVPVDVLRSLPKLTHFRLNAGRNIT 157
+ + N I L AF GL + L + + T +PV + LP+LT LN R
Sbjct: 167 ELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRL 225
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
+ F L+ L+L I+ L D AF GL+ + L++ N + + +G+ GL +
Sbjct: 226 IEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTAL 285
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
L L+ N I + ++ +L L + N+ LD E+ L + +++S+N
Sbjct: 286 HQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISH 345
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPEE----FISNSPLRTLSLARNQLRVLPRSVLRGQ 333
+ E F L +LR L LD + I E+ F L L+L N+++ + + G
Sbjct: 346 IAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGL 405
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALE 361
L L L NA+ + + F ++ L+
Sbjct: 406 EGLEHLNLGGNAIRSVQFDAFVKMKNLK 433
Score = 81.0 bits (191), Expect = 7e-15
Identities = 68/219 (31%), Positives = 102/219 (46%), Gaps = 4/219 (1%)
Query: 155 NITLHANM-FANTPPLKYLELSDAKITVLPDDAFLGLN-VLEQLNVWENEIANITAGAFR 212
NIT N F + PP+K L L+ +I L AF GL+ L L + +N I + AF+
Sbjct: 150 NITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFK 209
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISN 272
L +T L LN+NRI+ + F L L + RN+ L F GL + + +
Sbjct: 210 -LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEY 268
Query: 273 NVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLR 331
N + + L AL L L +SI + + S L L L+ N L L L
Sbjct: 269 NSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLA 328
Query: 332 GQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ L+ L LS+N+++ +A F LR+L +D NE+
Sbjct: 329 ELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEI 367
Score = 66.9 bits (156), Expect = 1e-10
Identities = 49/198 (24%), Positives = 86/198 (43%), Gaps = 3/198 (1%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
+N I+ L AF GL ++ + V L L L L+ +H +
Sbjct: 244 RNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGW 303
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
+ L L LS +T L +++ L+ L L + N I++I GAF+GL ++ VL L+
Sbjct: 304 SFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLD 363
Query: 224 KNRIQAL---PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKE 280
N I +G F+ L LT+ N + + F GL+ ++ + + N +++
Sbjct: 364 HNEISGTIEDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQF 423
Query: 281 AVFSNLPALRTLQLDLSS 298
F + L+ L + S
Sbjct: 424 DAFVKMKNLKELHISSDS 441
Score = 54.0 bits (124), Expect = 9e-07
Identities = 49/200 (24%), Positives = 89/200 (44%), Gaps = 2/200 (1%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L LS K++ + F L L+++ + NE+ + + H V+ L L N+I+++
Sbjct: 73 LNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVS-LFLQHNKIRSVE 131
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLP-ALR 290
+ L L + N+ + + F I+E+ ++ N TL+ F L +L
Sbjct: 132 GSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLL 191
Query: 291 TLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
TL+L + I +LP L L L RN++R++ +G L L L N +++L
Sbjct: 192 TLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLT 251
Query: 351 PELFADLRALETFVMDGNEL 370
F L + ++ N L
Sbjct: 252 DGAFWGLSKMHVLHLEYNSL 271
Score = 43.6 bits (98), Expect = 0.001
Identities = 33/123 (26%), Positives = 57/123 (46%), Gaps = 3/123 (2%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDD---AFL 188
T + + L L L+ RL+ + F L+ L+L +I+ +D AF
Sbjct: 320 TRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFS 379
Query: 189 GLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMR 248
GL+ L +L ++ N+I ++ AF GL + L+L N I+++ F L L +
Sbjct: 380 GLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHISS 439
Query: 249 NSF 251
+SF
Sbjct: 440 DSF 442
Score = 31.9 bits (69), Expect = 4.1
Identities = 15/33 (45%), Positives = 21/33 (63%)
Query: 338 SLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
SL LSYN ++E+ P F DL L+ ++ NEL
Sbjct: 72 SLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNEL 104
Score = 31.5 bits (68), Expect = 5.4
Identities = 37/146 (25%), Positives = 64/146 (43%), Gaps = 6/146 (4%)
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
+ ALP L S R LNL+ N +D F L ++QE+ ++NN LT ++ +
Sbjct: 59 LAALPGDL-PSWTRSLNLSY--NKLSEIDPAGFEDLPNLQEVYLNNN-ELTAVPSLGAAS 114
Query: 287 PALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
+ +L L + IR + + + L L L+ N + + + + L L+ N
Sbjct: 115 SHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNR 174
Query: 346 VAELAPELFADL-RALETFVMDGNEL 370
+ L F L R+L T + N +
Sbjct: 175 IGTLELGAFDGLSRSLLTLRLSKNRI 200
>BC036337-1|AAH36337.1| 811|Homo sapiens KIAA0644 gene product
protein.
Length = 811
Score = 89.4 bits (212), Expect = 2e-17
Identities = 70/232 (30%), Positives = 103/232 (44%), Gaps = 3/232 (1%)
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
L +L L + +LH F L+ L L + + L L L L N
Sbjct: 82 LGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYANGN 141
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG 261
EI+ ++ G+F GL ++ L L+ N + ALP +FA LL L + N R+L F
Sbjct: 142 EISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQ 201
Query: 262 LDHIQEIKISNN--VPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLA 318
L ++ + +S N P A F+ L +L +L L +S++ L + P L LSL
Sbjct: 202 LGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLR 261
Query: 319 RNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
NQL L G L L L N +++L L L +LE + GNEL
Sbjct: 262 GNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNEL 313
Score = 80.2 bits (189), Expect = 1e-14
Identities = 75/268 (27%), Positives = 112/268 (41%), Gaps = 5/268 (1%)
Query: 105 NAINPLNADAFKGLG-ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N I L+ F+ L + L + N Q P L L KL N L F
Sbjct: 93 NQIRSLHPKTFEKLSRLEELYLGNNLLQALAP-GTLAPLRKLRILYANGNEISRLSRGSF 151
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
L L L + LPD F L L L++ N I + AF L + L+L+
Sbjct: 152 EGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLS 211
Query: 224 KNRIQAL--PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEA 281
N +Q A FA L +L + NS ++L F+ L + + + N L
Sbjct: 212 ANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPE 271
Query: 282 VFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLT 340
F L ALR L+L+ + + +LP + L L L+ N+L L + +L L+
Sbjct: 272 AFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELS 331
Query: 341 LSYNAVAELAPELFADLRALETFVMDGN 368
L NA++ L+ ++FA AL +DGN
Sbjct: 332 LRNNALSALSGDIFAASPALYRLDLDGN 359
Score = 75.4 bits (177), Expect = 3e-13
Identities = 84/337 (24%), Positives = 129/337 (38%), Gaps = 11/337 (3%)
Query: 15 CPEQCWCTDGEELNYQCSRPSTNLIVGAR----PRDYVNIDCMGGELVCAEFPEIDTPAT 70
CPE+C C + L C+ ++ P D + +GG + D
Sbjct: 27 CPERCDCQHPQHL--LCTNRGLRVVPKTSSLPSPHDVLTYS-LGGNFI-TNITAFDFHRL 82
Query: 71 TQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGA 130
QL L L+ + L + + + + N + L L ++ N
Sbjct: 83 GQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYANGNE 142
Query: 131 QTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGL 190
+ + L L RL+ L +FA L YL L +I L +AF L
Sbjct: 143 ISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQL 202
Query: 191 NVLEQLNVWENEIANIT--AGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMR 248
L LN+ NE+ A F L +++ L L+ N +Q L +F PRL L++
Sbjct: 203 GKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRG 262
Query: 249 NSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 307
N +L E F GL+ ++E+++ N L A+ L +L L L + + L P F
Sbjct: 263 NQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFG 322
Query: 308 SNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
LR LSL N L L + L L L N
Sbjct: 323 HLGRLRELSLRNNALSALSGDIFAASPALYRLDLDGN 359
Score = 73.3 bits (172), Expect = 1e-12
Identities = 57/187 (30%), Positives = 89/187 (47%), Gaps = 3/187 (1%)
Query: 187 FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTM 246
F L L +L++ N+I ++ F L + L L N +QAL G A +L L
Sbjct: 79 FHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYA 138
Query: 247 MRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE- 305
N L +F GL+ + ++++ N L +AVF+ L L L L+ + IR L +
Sbjct: 139 NGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNA 198
Query: 306 FISNSPLRTLSLARNQLRVLPR--SVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 363
F LR L+L+ N+L+ R + L+SL LS N++ L P +F L L
Sbjct: 199 FAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLL 258
Query: 364 VMDGNEL 370
+ GN+L
Sbjct: 259 SLRGNQL 265
Score = 72.1 bits (169), Expect = 3e-12
Identities = 68/237 (28%), Positives = 101/237 (42%), Gaps = 6/237 (2%)
Query: 140 RSLPKLTHFR-LNAGRNI--TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQL 196
++ KL+ L G N+ L A L+ L + +I+ L +F GL L +L
Sbjct: 101 KTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKL 160
Query: 197 NVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR--YL 254
+ N + + F L N+ L L NRI+ L FA +L L + N +
Sbjct: 161 RLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLR 220
Query: 255 DSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLR 313
+ TF L + + +S N L +F +LP L L L + + L PE F LR
Sbjct: 221 HAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALR 280
Query: 314 TLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L L N+L LP ++L L +L LS N ++ L P F L L + N L
Sbjct: 281 ELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNAL 337
Score = 48.4 bits (110), Expect = 4e-05
Identities = 35/141 (24%), Positives = 63/141 (44%)
Query: 111 NADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLK 170
+A F L + ++ +A + + + + LP+L L + L F L+
Sbjct: 221 HAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALR 280
Query: 171 YLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
L L +++ LP L+ LE L++ NE++ + F L + LSL N + AL
Sbjct: 281 ELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNALSAL 340
Query: 231 PAGLFASTPRLLNLTMMRNSF 251
+FA++P L L + N +
Sbjct: 341 SGDIFAASPALYRLDLDGNGW 361
Score = 35.1 bits (77), Expect = 0.44
Identities = 40/157 (25%), Positives = 61/157 (38%), Gaps = 23/157 (14%)
Query: 215 HNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV 274
H+V SL N I + A F +L L + N R L +TF L ++E+ + NN+
Sbjct: 59 HDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNL 118
Query: 275 PLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQT 334
L L+ +R+L R L N++ L R G
Sbjct: 119 LQALAPGT-------------LAPLRKL----------RILYANGNEISRLSRGSFEGLE 155
Query: 335 QLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
L L L NA+ L +FA L L ++ N ++
Sbjct: 156 SLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIR 192
>AB014544-1|BAA31619.2| 887|Homo sapiens KIAA0644 protein protein.
Length = 887
Score = 89.4 bits (212), Expect = 2e-17
Identities = 70/232 (30%), Positives = 103/232 (44%), Gaps = 3/232 (1%)
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
L +L L + +LH F L+ L L + + L L L L N
Sbjct: 158 LGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYANGN 217
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG 261
EI+ ++ G+F GL ++ L L+ N + ALP +FA LL L + N R+L F
Sbjct: 218 EISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQ 277
Query: 262 LDHIQEIKISNN--VPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLA 318
L ++ + +S N P A F+ L +L +L L +S++ L + P L LSL
Sbjct: 278 LGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLR 337
Query: 319 RNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
NQL L G L L L N +++L L L +LE + GNEL
Sbjct: 338 GNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNEL 389
Score = 80.2 bits (189), Expect = 1e-14
Identities = 75/268 (27%), Positives = 112/268 (41%), Gaps = 5/268 (1%)
Query: 105 NAINPLNADAFKGLG-ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N I L+ F+ L + L + N Q P L L KL N L F
Sbjct: 169 NQIRSLHPKTFEKLSRLEELYLGNNLLQALAP-GTLAPLRKLRILYANGNEISRLSRGSF 227
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
L L L + LPD F L L L++ N I + AF L + L+L+
Sbjct: 228 EGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLS 287
Query: 224 KNRIQAL--PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEA 281
N +Q A FA L +L + NS ++L F+ L + + + N L
Sbjct: 288 ANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPE 347
Query: 282 VFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLT 340
F L ALR L+L+ + + +LP + L L L+ N+L L + +L L+
Sbjct: 348 AFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELS 407
Query: 341 LSYNAVAELAPELFADLRALETFVMDGN 368
L NA++ L+ ++FA AL +DGN
Sbjct: 408 LRNNALSALSGDIFAASPALYRLDLDGN 435
Score = 75.4 bits (177), Expect = 3e-13
Identities = 84/337 (24%), Positives = 129/337 (38%), Gaps = 11/337 (3%)
Query: 15 CPEQCWCTDGEELNYQCSRPSTNLIVGAR----PRDYVNIDCMGGELVCAEFPEIDTPAT 70
CPE+C C + L C+ ++ P D + +GG + D
Sbjct: 103 CPERCDCQHPQHL--LCTNRGLRVVPKTSSLPSPHDVLTYS-LGGNFI-TNITAFDFHRL 158
Query: 71 TQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGA 130
QL L L+ + L + + + + N + L L ++ N
Sbjct: 159 GQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYANGNE 218
Query: 131 QTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGL 190
+ + L L RL+ L +FA L YL L +I L +AF L
Sbjct: 219 ISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQL 278
Query: 191 NVLEQLNVWENEIANIT--AGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMR 248
L LN+ NE+ A F L +++ L L+ N +Q L +F PRL L++
Sbjct: 279 GKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRG 338
Query: 249 NSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFI 307
N +L E F GL+ ++E+++ N L A+ L +L L L + + L P F
Sbjct: 339 NQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFG 398
Query: 308 SNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
LR LSL N L L + L L L N
Sbjct: 399 HLGRLRELSLRNNALSALSGDIFAASPALYRLDLDGN 435
Score = 73.3 bits (172), Expect = 1e-12
Identities = 57/187 (30%), Positives = 89/187 (47%), Gaps = 3/187 (1%)
Query: 187 FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTM 246
F L L +L++ N+I ++ F L + L L N +QAL G A +L L
Sbjct: 155 FHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYA 214
Query: 247 MRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE- 305
N L +F GL+ + ++++ N L +AVF+ L L L L+ + IR L +
Sbjct: 215 NGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNA 274
Query: 306 FISNSPLRTLSLARNQLRVLPR--SVLRGQTQLTSLTLSYNAVAELAPELFADLRALETF 363
F LR L+L+ N+L+ R + L+SL LS N++ L P +F L L
Sbjct: 275 FAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLL 334
Query: 364 VMDGNEL 370
+ GN+L
Sbjct: 335 SLRGNQL 341
Score = 72.1 bits (169), Expect = 3e-12
Identities = 68/237 (28%), Positives = 101/237 (42%), Gaps = 6/237 (2%)
Query: 140 RSLPKLTHFR-LNAGRNI--TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQL 196
++ KL+ L G N+ L A L+ L + +I+ L +F GL L +L
Sbjct: 177 KTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKL 236
Query: 197 NVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR--YL 254
+ N + + F L N+ L L NRI+ L FA +L L + N +
Sbjct: 237 RLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLR 296
Query: 255 DSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLR 313
+ TF L + + +S N L +F +LP L L L + + L PE F LR
Sbjct: 297 HAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALR 356
Query: 314 TLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L L N+L LP ++L L +L LS N ++ L P F L L + N L
Sbjct: 357 ELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNAL 413
Score = 48.4 bits (110), Expect = 4e-05
Identities = 35/141 (24%), Positives = 63/141 (44%)
Query: 111 NADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLK 170
+A F L + ++ +A + + + + LP+L L + L F L+
Sbjct: 297 HAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALR 356
Query: 171 YLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
L L +++ LP L+ LE L++ NE++ + F L + LSL N + AL
Sbjct: 357 ELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNALSAL 416
Query: 231 PAGLFASTPRLLNLTMMRNSF 251
+FA++P L L + N +
Sbjct: 417 SGDIFAASPALYRLDLDGNGW 437
Score = 35.1 bits (77), Expect = 0.44
Identities = 40/157 (25%), Positives = 61/157 (38%), Gaps = 23/157 (14%)
Query: 215 HNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV 274
H+V SL N I + A F +L L + N R L +TF L ++E+ + NN+
Sbjct: 135 HDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNL 194
Query: 275 PLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQT 334
L L+ +R+L R L N++ L R G
Sbjct: 195 LQALAPGT-------------LAPLRKL----------RILYANGNEISRLSRGSFEGLE 231
Query: 335 QLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
L L L NA+ L +FA L L ++ N ++
Sbjct: 232 SLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIR 268
>BC113617-1|AAI13618.1| 757|Homo sapiens relaxin/insulin-like
family peptide receptor 1 protein.
Length = 757
Score = 88.2 bits (209), Expect = 4e-17
Identities = 62/195 (31%), Positives = 97/195 (49%), Gaps = 2/195 (1%)
Query: 179 ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFAST 238
I LP D F + L++L + N+I +I+ AFRGL+++T L L+ NRI L G+F
Sbjct: 138 IRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDL 197
Query: 239 PRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKE-AVFSNLPALRTLQLDLS 297
RL L + N + TF GL+ + + + NNV L + + ++P L L L+ +
Sbjct: 198 HRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGN 257
Query: 298 SIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFAD 356
I L FIS S L L + +N++ L + +L L L N + L P +F D
Sbjct: 258 HIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKD 317
Query: 357 LRALETFVMDGNELQ 371
L+ L + N +Q
Sbjct: 318 LKELSQLNLSYNPIQ 332
Score = 74.1 bits (174), Expect = 8e-13
Identities = 57/215 (26%), Positives = 93/215 (43%), Gaps = 2/215 (0%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L + F N L+ L L + KIT + AF GLN L +L + N I + G F LH +
Sbjct: 141 LPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRL 200
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF-RYLDSETFRGLDHIQEIKISNNVPL 276
L + N + + F L+ L +M N R D + + + + + N
Sbjct: 201 EWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIH 260
Query: 277 TLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
L+ F + L L + + I L E F L L L N++ LP + + +
Sbjct: 261 NLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKE 320
Query: 336 LTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L+ L LSYN + ++ F L L++ ++G E+
Sbjct: 321 LSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEI 355
Score = 61.7 bits (143), Expect = 4e-09
Identities = 58/229 (25%), Positives = 97/229 (42%), Gaps = 2/229 (0%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
+P D ++ L L + ++ F L L LS +IT L F L+ L
Sbjct: 141 LPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRL 200
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP-AGLFASTPRLLNLTMMRNSFR 252
E L + +N ++ I+ F GL+++ +L L N + LP L PRL L + N
Sbjct: 201 EWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIH 260
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SP 311
L + TF ++ + + N L E F+ L L L L + I LP +
Sbjct: 261 NLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKE 320
Query: 312 LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 360
L L+L+ N ++ + + +L SL+L ++ + +F L L
Sbjct: 321 LSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQRMFRPLMNL 369
Score = 54.8 bits (126), Expect = 5e-07
Identities = 45/157 (28%), Positives = 70/157 (44%), Gaps = 2/157 (1%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
NVT +SL N I+ LP F + L L + N + FRGL+ + ++ +S+N
Sbjct: 127 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 186
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLP-RSVLRGQ 333
LK VF +L L L ++ + + + P F + L L L N L LP + + +
Sbjct: 187 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 246
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+L L L N + L F L VM N++
Sbjct: 247 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKI 283
>BC112142-1|AAI12143.1| 757|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 7 protein.
Length = 757
Score = 88.2 bits (209), Expect = 4e-17
Identities = 62/195 (31%), Positives = 97/195 (49%), Gaps = 2/195 (1%)
Query: 179 ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFAST 238
I LP D F + L++L + N+I +I+ AFRGL+++T L L+ NRI L G+F
Sbjct: 138 IRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDL 197
Query: 239 PRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKE-AVFSNLPALRTLQLDLS 297
RL L + N + TF GL+ + + + NNV L + + ++P L L L+ +
Sbjct: 198 HRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGN 257
Query: 298 SIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFAD 356
I L FIS S L L + +N++ L + +L L L N + L P +F D
Sbjct: 258 HIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKD 317
Query: 357 LRALETFVMDGNELQ 371
L+ L + N +Q
Sbjct: 318 LKELSQLNLSYNPIQ 332
Score = 74.1 bits (174), Expect = 8e-13
Identities = 57/215 (26%), Positives = 93/215 (43%), Gaps = 2/215 (0%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L + F N L+ L L + KIT + AF GLN L +L + N I + G F LH +
Sbjct: 141 LPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRL 200
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF-RYLDSETFRGLDHIQEIKISNNVPL 276
L + N + + F L+ L +M N R D + + + + + N
Sbjct: 201 EWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIH 260
Query: 277 TLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
L+ F + L L + + I L E F L L L N++ LP + + +
Sbjct: 261 NLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKE 320
Query: 336 LTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L+ L LSYN + ++ F L L++ ++G E+
Sbjct: 321 LSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEI 355
Score = 61.7 bits (143), Expect = 4e-09
Identities = 58/229 (25%), Positives = 97/229 (42%), Gaps = 2/229 (0%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
+P D ++ L L + ++ F L L LS +IT L F L+ L
Sbjct: 141 LPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRL 200
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP-AGLFASTPRLLNLTMMRNSFR 252
E L + +N ++ I+ F GL+++ +L L N + LP L PRL L + N
Sbjct: 201 EWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIH 260
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SP 311
L + TF ++ + + N L E F+ L L L L + I LP +
Sbjct: 261 NLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKE 320
Query: 312 LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 360
L L+L+ N ++ + + +L SL+L ++ + +F L L
Sbjct: 321 LSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQRMFRPLMNL 369
Score = 54.8 bits (126), Expect = 5e-07
Identities = 45/157 (28%), Positives = 70/157 (44%), Gaps = 2/157 (1%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
NVT +SL N I+ LP F + L L + N + FRGL+ + ++ +S+N
Sbjct: 127 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 186
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLP-RSVLRGQ 333
LK VF +L L L ++ + + + P F + L L L N L LP + + +
Sbjct: 187 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 246
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+L L L N + L F L VM N++
Sbjct: 247 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKI 283
>AY899850-1|AAX85198.1| 724|Homo sapiens LGR7.10 protein.
Length = 724
Score = 88.2 bits (209), Expect = 4e-17
Identities = 62/195 (31%), Positives = 97/195 (49%), Gaps = 2/195 (1%)
Query: 179 ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFAST 238
I LP D F + L++L + N+I +I+ AFRGL+++T L L+ NRI L G+F
Sbjct: 105 IRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDL 164
Query: 239 PRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKE-AVFSNLPALRTLQLDLS 297
RL L + N + TF GL+ + + + NNV L + + ++P L L L+ +
Sbjct: 165 HRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGN 224
Query: 298 SIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFAD 356
I L FIS S L L + +N++ L + +L L L N + L P +F D
Sbjct: 225 HIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKD 284
Query: 357 LRALETFVMDGNELQ 371
L+ L + N +Q
Sbjct: 285 LKELSQLNLSYNPIQ 299
Score = 74.1 bits (174), Expect = 8e-13
Identities = 57/215 (26%), Positives = 93/215 (43%), Gaps = 2/215 (0%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L + F N L+ L L + KIT + AF GLN L +L + N I + G F LH +
Sbjct: 108 LPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRL 167
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF-RYLDSETFRGLDHIQEIKISNNVPL 276
L + N + + F L+ L +M N R D + + + + + N
Sbjct: 168 EWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIH 227
Query: 277 TLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
L+ F + L L + + I L E F L L L N++ LP + + +
Sbjct: 228 NLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKE 287
Query: 336 LTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L+ L LSYN + ++ F L L++ ++G E+
Sbjct: 288 LSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEI 322
Score = 61.7 bits (143), Expect = 4e-09
Identities = 58/229 (25%), Positives = 97/229 (42%), Gaps = 2/229 (0%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
+P D ++ L L + ++ F L L LS +IT L F L+ L
Sbjct: 108 LPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRL 167
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP-AGLFASTPRLLNLTMMRNSFR 252
E L + +N ++ I+ F GL+++ +L L N + LP L PRL L + N
Sbjct: 168 EWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIH 227
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SP 311
L + TF ++ + + N L E F+ L L L L + I LP +
Sbjct: 228 NLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKE 287
Query: 312 LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 360
L L+L+ N ++ + + +L SL+L ++ + +F L L
Sbjct: 288 LSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQRMFRPLMNL 336
Score = 54.8 bits (126), Expect = 5e-07
Identities = 45/157 (28%), Positives = 70/157 (44%), Gaps = 2/157 (1%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
NVT +SL N I+ LP F + L L + N + FRGL+ + ++ +S+N
Sbjct: 94 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 153
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLP-RSVLRGQ 333
LK VF +L L L ++ + + + P F + L L L N L LP + + +
Sbjct: 154 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 213
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+L L L N + L F L VM N++
Sbjct: 214 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKI 250
>AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 967
Score = 88.2 bits (209), Expect = 4e-17
Identities = 57/206 (27%), Positives = 97/206 (47%), Gaps = 2/206 (0%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P YL+LS +T L F L LE+L + N +++I AF GL+++ +L L N+
Sbjct: 66 PLTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQ 125
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
+ +PA P L +L + N + +F GL ++ + + +N + +NL
Sbjct: 126 LGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNL 185
Query: 287 PALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
PAL+ + L L+ I +P+ N + L L L N+++ L G L +L L+YN
Sbjct: 186 PALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNK 245
Query: 346 VAELAPELFADLRALETFVMDGNELQ 371
+ E P L L+ N ++
Sbjct: 246 LQEF-PVAIRTLGRLQELGFHNNNIK 270
Score = 84.2 bits (199), Expect = 7e-16
Identities = 71/268 (26%), Positives = 113/268 (42%), Gaps = 3/268 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ + AF GL ++M +P + L LP L RL+A + F
Sbjct: 100 NHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFE 159
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L++L L D +T +P A L L+ + + N I++I AF+ L ++ VL L+
Sbjct: 160 GLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHN 219
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRIQ L F L L + N + R L +QE+ NN + E F
Sbjct: 220 NRIQHLGTHSFEGLHNLETLDLNYNKLQEF-PVAIRTLGRLQELGFHNNNIKAIPEKAFM 278
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
P L+T+ + I+ + P L TLSL + + L+G T L LTL+
Sbjct: 279 GNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSL-NGAMDIQEFPDLKGTTSLEILTLTR 337
Query: 344 NAVAELAPELFADLRALETFVMDGNELQ 371
+ L + L L + N+++
Sbjct: 338 AGIRLLPSGMCQQLPRLRVLELSHNQIE 365
Score = 76.6 bits (180), Expect = 1e-13
Identities = 73/289 (25%), Positives = 120/289 (41%), Gaps = 25/289 (8%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I+ + +F+GL + + A T +PV L +LP L L R + F
Sbjct: 148 NLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQ 207
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N L L L + +I L +F GL+ LE L++ N++ A R L + L +
Sbjct: 208 NLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPV-AIRTLGRLQELGFHN 266
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP--------- 275
N I+A+P F P L + N +++ F+ L + + ++ +
Sbjct: 267 NNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKG 326
Query: 276 ------LTLKEA--------VFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 321
LTL A + LP LR L+L + I ELP L + L N+
Sbjct: 327 TTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHRCQK-LEEIGLQHNR 385
Query: 322 LRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ + + L +L LS+NA+ + PE F+ L +L + N+L
Sbjct: 386 IWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQL 434
Score = 72.9 bits (171), Expect = 2e-12
Identities = 55/248 (22%), Positives = 102/248 (41%)
Query: 120 ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKI 179
+TA + + T + + L L RL+ + F+ LK L L + ++
Sbjct: 67 LTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQL 126
Query: 180 TVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTP 239
+P +A L L+ L + N I+ + +F GL ++ L L+ N + +P + P
Sbjct: 127 GGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLP 186
Query: 240 RLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI 299
L +T+ N ++ F+ L + + + NN L F L L TL L+ + +
Sbjct: 187 ALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKL 246
Query: 300 RELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRA 359
+E P + L+ L N ++ +P G L ++ N + + F L
Sbjct: 247 QEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPK 306
Query: 360 LETFVMDG 367
L T ++G
Sbjct: 307 LHTLSLNG 314
Score = 70.1 bits (164), Expect = 1e-11
Identities = 82/305 (26%), Positives = 127/305 (41%), Gaps = 15/305 (4%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVF---KNAINPLNADAFKGLGI 120
EI A LP+L +L +S + VV N I L +F+GL
Sbjct: 176 EIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHN 235
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
+ N PV +R+L +L + + F P L+ + D I
Sbjct: 236 LETLDLNYNKLQEFPV-AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQ 294
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGA-FRGLHNVTVLSLNKNRIQALPAGLFASTP 239
+ AF L L L++ N +I +G ++ +L+L + I+ LP+G+ P
Sbjct: 295 FVGRSAFQYLPKLHTLSL--NGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLP 352
Query: 240 RLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI 299
RL L + N L S ++EI + +N + FS L +L+ L L ++I
Sbjct: 353 RLRVLELSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAI 410
Query: 300 REL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN-AVAE-LAPELFAD 356
R + PE F + L L L NQL LP + L G L L L N A+++ + + F
Sbjct: 411 RSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGG---LMHLKLKGNLALSQAFSKDSFPK 467
Query: 357 LRALE 361
LR LE
Sbjct: 468 LRILE 472
Score = 68.1 bits (159), Expect = 5e-11
Identities = 55/239 (23%), Positives = 107/239 (44%), Gaps = 2/239 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L F L + + + +P L L L + + A
Sbjct: 76 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 135
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
P L+ L L I+++P+ +F GL+ L L + +N + I A L + ++L
Sbjct: 136 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL 195
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRI +P F + L+ L + N ++L + +F GL +++ + ++ N A+
Sbjct: 196 NRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAI-R 254
Query: 285 NLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS 342
L L+ L ++I+ +PE+ F+ N L+T+ N ++ + RS + +L +L+L+
Sbjct: 255 TLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLN 313
>AF190500-1|AAG17167.1| 757|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 7 protein.
Length = 757
Score = 88.2 bits (209), Expect = 4e-17
Identities = 62/195 (31%), Positives = 97/195 (49%), Gaps = 2/195 (1%)
Query: 179 ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFAST 238
I LP D F + L++L + N+I +I+ AFRGL+++T L L+ NRI L G+F
Sbjct: 138 IRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDL 197
Query: 239 PRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKE-AVFSNLPALRTLQLDLS 297
RL L + N + TF GL+ + + + NNV L + + ++P L L L+ +
Sbjct: 198 HRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGN 257
Query: 298 SIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFAD 356
I L FIS S L L + +N++ L + +L L L N + L P +F D
Sbjct: 258 HIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKD 317
Query: 357 LRALETFVMDGNELQ 371
L+ L + N +Q
Sbjct: 318 LKELSQLNLSYNPIQ 332
Score = 74.1 bits (174), Expect = 8e-13
Identities = 57/215 (26%), Positives = 93/215 (43%), Gaps = 2/215 (0%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L + F N L+ L L + KIT + AF GLN L +L + N I + G F LH +
Sbjct: 141 LPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRL 200
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF-RYLDSETFRGLDHIQEIKISNNVPL 276
L + N + + F L+ L +M N R D + + + + + N
Sbjct: 201 EWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIH 260
Query: 277 TLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
L+ F + L L + + I L E F L L L N++ LP + + +
Sbjct: 261 NLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKE 320
Query: 336 LTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L+ L LSYN + ++ F L L++ ++G E+
Sbjct: 321 LSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEI 355
Score = 61.7 bits (143), Expect = 4e-09
Identities = 58/229 (25%), Positives = 97/229 (42%), Gaps = 2/229 (0%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
+P D ++ L L + ++ F L L LS +IT L F L+ L
Sbjct: 141 LPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRL 200
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP-AGLFASTPRLLNLTMMRNSFR 252
E L + +N ++ I+ F GL+++ +L L N + LP L PRL L + N
Sbjct: 201 EWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIH 260
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SP 311
L + TF ++ + + N L E F+ L L L L + I LP +
Sbjct: 261 NLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKE 320
Query: 312 LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 360
L L+L+ N ++ + + +L SL+L ++ + +F L L
Sbjct: 321 LSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQRMFRPLMNL 369
Score = 54.8 bits (126), Expect = 5e-07
Identities = 45/157 (28%), Positives = 70/157 (44%), Gaps = 2/157 (1%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
NVT +SL N I+ LP F + L L + N + FRGL+ + ++ +S+N
Sbjct: 127 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 186
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLP-RSVLRGQ 333
LK VF +L L L ++ + + + P F + L L L N L LP + + +
Sbjct: 187 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 246
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+L L L N + L F L VM N++
Sbjct: 247 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKI 283
>AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein.
Length = 928
Score = 88.2 bits (209), Expect = 4e-17
Identities = 57/206 (27%), Positives = 97/206 (47%), Gaps = 2/206 (0%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P YL+LS +T L F L LE+L + N +++I AF GL+++ +L L N+
Sbjct: 27 PLTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQ 86
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
+ +PA P L +L + N + +F GL ++ + + +N + +NL
Sbjct: 87 LGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNL 146
Query: 287 PALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
PAL+ + L L+ I +P+ N + L L L N+++ L G L +L L+YN
Sbjct: 147 PALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNK 206
Query: 346 VAELAPELFADLRALETFVMDGNELQ 371
+ E P L L+ N ++
Sbjct: 207 LQEF-PVAIRTLGRLQELGFHNNNIK 231
Score = 84.2 bits (199), Expect = 7e-16
Identities = 71/268 (26%), Positives = 113/268 (42%), Gaps = 3/268 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ + AF GL ++M +P + L LP L RL+A + F
Sbjct: 61 NHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFE 120
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L++L L D +T +P A L L+ + + N I++I AF+ L ++ VL L+
Sbjct: 121 GLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHN 180
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRIQ L F L L + N + R L +QE+ NN + E F
Sbjct: 181 NRIQHLGTHSFEGLHNLETLDLNYNKLQEF-PVAIRTLGRLQELGFHNNNIKAIPEKAFM 239
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
P L+T+ + I+ + P L TLSL + + L+G T L LTL+
Sbjct: 240 GNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSL-NGAMDIQEFPDLKGTTSLEILTLTR 298
Query: 344 NAVAELAPELFADLRALETFVMDGNELQ 371
+ L + L L + N+++
Sbjct: 299 AGIRLLPSGMCQQLPRLRVLELSHNQIE 326
Score = 76.6 bits (180), Expect = 1e-13
Identities = 73/289 (25%), Positives = 120/289 (41%), Gaps = 25/289 (8%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I+ + +F+GL + + A T +PV L +LP L L R + F
Sbjct: 109 NLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQ 168
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N L L L + +I L +F GL+ LE L++ N++ A R L + L +
Sbjct: 169 NLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPV-AIRTLGRLQELGFHN 227
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP--------- 275
N I+A+P F P L + N +++ F+ L + + ++ +
Sbjct: 228 NNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKG 287
Query: 276 ------LTLKEA--------VFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 321
LTL A + LP LR L+L + I ELP L + L N+
Sbjct: 288 TTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHRCQK-LEEIGLQHNR 346
Query: 322 LRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ + + L +L LS+NA+ + PE F+ L +L + N+L
Sbjct: 347 IWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQL 395
Score = 72.9 bits (171), Expect = 2e-12
Identities = 55/248 (22%), Positives = 102/248 (41%)
Query: 120 ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKI 179
+TA + + T + + L L RL+ + F+ LK L L + ++
Sbjct: 28 LTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQL 87
Query: 180 TVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTP 239
+P +A L L+ L + N I+ + +F GL ++ L L+ N + +P + P
Sbjct: 88 GGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLP 147
Query: 240 RLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI 299
L +T+ N ++ F+ L + + + NN L F L L TL L+ + +
Sbjct: 148 ALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKL 207
Query: 300 RELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRA 359
+E P + L+ L N ++ +P G L ++ N + + F L
Sbjct: 208 QEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPK 267
Query: 360 LETFVMDG 367
L T ++G
Sbjct: 268 LHTLSLNG 275
Score = 70.1 bits (164), Expect = 1e-11
Identities = 82/305 (26%), Positives = 127/305 (41%), Gaps = 15/305 (4%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVF---KNAINPLNADAFKGLGI 120
EI A LP+L +L +S + VV N I L +F+GL
Sbjct: 137 EIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHN 196
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
+ N PV +R+L +L + + F P L+ + D I
Sbjct: 197 LETLDLNYNKLQEFPV-AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQ 255
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGA-FRGLHNVTVLSLNKNRIQALPAGLFASTP 239
+ AF L L L++ N +I +G ++ +L+L + I+ LP+G+ P
Sbjct: 256 FVGRSAFQYLPKLHTLSL--NGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLP 313
Query: 240 RLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI 299
RL L + N L S ++EI + +N + FS L +L+ L L ++I
Sbjct: 314 RLRVLELSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAI 371
Query: 300 REL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN-AVAE-LAPELFAD 356
R + PE F + L L L NQL LP + L G L L L N A+++ + + F
Sbjct: 372 RSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGG---LMHLKLKGNLALSQAFSKDSFPK 428
Query: 357 LRALE 361
LR LE
Sbjct: 429 LRILE 433
Score = 68.1 bits (159), Expect = 5e-11
Identities = 55/239 (23%), Positives = 107/239 (44%), Gaps = 2/239 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L F L + + + +P L L L + + A
Sbjct: 37 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 96
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
P L+ L L I+++P+ +F GL+ L L + +N + I A L + ++L
Sbjct: 97 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL 156
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRI +P F + L+ L + N ++L + +F GL +++ + ++ N A+
Sbjct: 157 NRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAI-R 215
Query: 285 NLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS 342
L L+ L ++I+ +PE+ F+ N L+T+ N ++ + RS + +L +L+L+
Sbjct: 216 TLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLN 274
>BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 86.6 bits (205), Expect = 1e-16
Identities = 61/230 (26%), Positives = 101/230 (43%), Gaps = 2/230 (0%)
Query: 139 LRSLPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
L SL L RL AG +T + F LK L L + ++ +P +A L L+ L
Sbjct: 86 LPSLRFLEELRL-AGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLR 144
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSE 257
+ N I+ + F GLH++ L L+ N + +P F S L +T+ N ++
Sbjct: 145 LDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDY 204
Query: 258 TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSL 317
F L + + + NN +L + F L +L TL L+ +++ E P + S L+ L
Sbjct: 205 AFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGF 264
Query: 318 ARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 367
N +R +P G L ++ N + + F L L T ++G
Sbjct: 265 HSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNG 314
Score = 86.2 bits (204), Expect = 2e-16
Identities = 71/267 (26%), Positives = 118/267 (44%), Gaps = 5/267 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + + +A + L + +A + VP L L H L+ + F
Sbjct: 124 NQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFR 183
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
+ L+ + L+ KI +PD AF L+ L L++ N I ++ F GLH++ L LN
Sbjct: 184 SLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNY 243
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N + P + + L L N+ R + + F G + I +N + + F
Sbjct: 244 NNLDEFPTAI-RTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQ 302
Query: 285 NLPALRTLQLD-LSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+LP LRTL L+ S I E P + + L +L+L Q+ LP++V L L LSY
Sbjct: 303 HLPELRTLTLNGASQITEFP-DLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSY 361
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
N + +L F+ + L+ + NE+
Sbjct: 362 NLLEDLPS--FSVCQKLQKIDLRHNEI 386
Score = 85.0 bits (201), Expect = 4e-16
Identities = 73/269 (27%), Positives = 124/269 (46%), Gaps = 5/269 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
NA+ + AF GL ++M VP + L++L L RL+A + + F+
Sbjct: 100 NALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFS 159
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L++L L D +T +P AF L+ L+ + + N+I +I AF L ++ VL L+
Sbjct: 160 GLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHN 219
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRI +L F L L + N+ + R L +++E+ +N ++ E F
Sbjct: 220 NRIHSLGKKCFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELGFHSNNIRSIPEKAFV 278
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSP-LRTLSL-ARNQLRVLPRSVLRGQTQLTSLTLS 342
P+L T+ + I+ + + P LRTL+L +Q+ P L G L SLTL+
Sbjct: 279 GNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPD--LTGTANLESLTLT 336
Query: 343 YNAVAELAPELFADLRALETFVMDGNELQ 371
++ L + L L+ + N L+
Sbjct: 337 GAQISSLPQTVCNQLPNLQVLDLSYNLLE 365
Score = 82.6 bits (195), Expect = 2e-15
Identities = 56/202 (27%), Positives = 94/202 (46%), Gaps = 2/202 (0%)
Query: 171 YLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
YL+LS I+ L + L LE+L + N + I GAF GL+++ VL L N+++ +
Sbjct: 70 YLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHV 129
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
P + L +L + N Y+ F GL ++ + + +N + F +L AL+
Sbjct: 130 PTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQ 189
Query: 291 TLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAEL 349
+ L L+ I +P+ N S L L L N++ L + G L +L L+YN + E
Sbjct: 190 AMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF 249
Query: 350 APELFADLRALETFVMDGNELQ 371
P L L+ N ++
Sbjct: 250 -PTAIRTLSNLKELGFHSNNIR 270
Score = 72.9 bits (171), Expect = 2e-12
Identities = 64/267 (23%), Positives = 111/267 (41%), Gaps = 3/267 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I+ L + L + A T +P L L L + +
Sbjct: 76 NNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQ 135
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N L+ L L I+ +P F GL+ L L + +N + I AFR L + ++L
Sbjct: 136 NLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLAL 195
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N+I +P F + L+ L + N L + F GL ++ + ++ N L
Sbjct: 196 NKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYN-NLDEFPTAIR 254
Query: 285 NLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
L L+ L ++IR +PE+ F+ N L T+ N ++ + RS + +L +LTL+
Sbjct: 255 TLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNG 314
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
+ P+L LE+ + G ++
Sbjct: 315 ASQITEFPDLTGTAN-LESLTLTGAQI 340
Score = 50.8 bits (116), Expect = 8e-06
Identities = 40/137 (29%), Positives = 70/137 (51%), Gaps = 7/137 (5%)
Query: 163 FANTPPLKYLELSDA-KITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLS 221
F + P L+ L L+ A +IT PD G LE L + +I+++ L N+ VL
Sbjct: 301 FQHLPELRTLTLNGASQITEFPD--LTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLD 358
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEA 281
L+ N ++ LP+ F+ +L + + N + +TF+ L ++ + ++ N +
Sbjct: 359 LSYNLLEDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPN 416
Query: 282 VFSNLPALRTLQLDLSS 298
FS LP+L ++LDLSS
Sbjct: 417 AFSTLPSL--IKLDLSS 431
Score = 49.2 bits (112), Expect = 3e-05
Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 9/193 (4%)
Query: 103 FKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANM 162
+ N I + AF+ L + N +Q T D L L L + +L +
Sbjct: 289 YDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPD-LTGTANLESLTLTGAQISSLPQTV 347
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
P L+ L+LS + LP +F L+++++ NEI I F+ L ++ L+L
Sbjct: 348 CNQLPNLQVLDLSYNLLEDLP--SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNL 405
Query: 223 NKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAV 282
N+I + F++ P L+ L + N L S GL + +K++ N L+ +
Sbjct: 406 AWNKIAIIHPNAFSTLPSLIKLDLSSN---LLSSFPITGLHGLTHLKLTGN--HALQSLI 460
Query: 283 FS-NLPALRTLQL 294
S N P L+ +++
Sbjct: 461 SSENFPELKVIEM 473
>BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 86.6 bits (205), Expect = 1e-16
Identities = 61/230 (26%), Positives = 101/230 (43%), Gaps = 2/230 (0%)
Query: 139 LRSLPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
L SL L RL AG +T + F LK L L + ++ +P +A L L+ L
Sbjct: 86 LPSLRFLEELRL-AGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLR 144
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSE 257
+ N I+ + F GLH++ L L+ N + +P F S L +T+ N ++
Sbjct: 145 LDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDY 204
Query: 258 TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSL 317
F L + + + NN +L + F L +L TL L+ +++ E P + S L+ L
Sbjct: 205 AFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGF 264
Query: 318 ARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 367
N +R +P G L ++ N + + F L L T ++G
Sbjct: 265 HSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNG 314
Score = 86.2 bits (204), Expect = 2e-16
Identities = 71/267 (26%), Positives = 118/267 (44%), Gaps = 5/267 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + + +A + L + +A + VP L L H L+ + F
Sbjct: 124 NQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFR 183
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
+ L+ + L+ KI +PD AF L+ L L++ N I ++ F GLH++ L LN
Sbjct: 184 SLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNY 243
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N + P + + L L N+ R + + F G + I +N + + F
Sbjct: 244 NNLDEFPTAI-RTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQ 302
Query: 285 NLPALRTLQLD-LSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+LP LRTL L+ S I E P + + L +L+L Q+ LP++V L L LSY
Sbjct: 303 HLPELRTLTLNGASQITEFP-DLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSY 361
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
N + +L F+ + L+ + NE+
Sbjct: 362 NLLEDLPS--FSVCQKLQKIDLRHNEI 386
Score = 85.0 bits (201), Expect = 4e-16
Identities = 73/269 (27%), Positives = 124/269 (46%), Gaps = 5/269 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
NA+ + AF GL ++M VP + L++L L RL+A + + F+
Sbjct: 100 NALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFS 159
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L++L L D +T +P AF L+ L+ + + N+I +I AF L ++ VL L+
Sbjct: 160 GLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHN 219
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRI +L F L L + N+ + R L +++E+ +N ++ E F
Sbjct: 220 NRIHSLGKKCFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELGFHSNNIRSIPEKAFV 278
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSP-LRTLSL-ARNQLRVLPRSVLRGQTQLTSLTLS 342
P+L T+ + I+ + + P LRTL+L +Q+ P L G L SLTL+
Sbjct: 279 GNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPD--LTGTANLESLTLT 336
Query: 343 YNAVAELAPELFADLRALETFVMDGNELQ 371
++ L + L L+ + N L+
Sbjct: 337 GAQISSLPQTVCNQLPNLQVLDLSYNLLE 365
Score = 82.6 bits (195), Expect = 2e-15
Identities = 56/202 (27%), Positives = 94/202 (46%), Gaps = 2/202 (0%)
Query: 171 YLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
YL+LS I+ L + L LE+L + N + I GAF GL+++ VL L N+++ +
Sbjct: 70 YLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHV 129
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
P + L +L + N Y+ F GL ++ + + +N + F +L AL+
Sbjct: 130 PTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQ 189
Query: 291 TLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAEL 349
+ L L+ I +P+ N S L L L N++ L + G L +L L+YN + E
Sbjct: 190 AMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF 249
Query: 350 APELFADLRALETFVMDGNELQ 371
P L L+ N ++
Sbjct: 250 -PTAIRTLSNLKELGFHSNNIR 270
Score = 72.9 bits (171), Expect = 2e-12
Identities = 64/267 (23%), Positives = 111/267 (41%), Gaps = 3/267 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I+ L + L + A T +P L L L + +
Sbjct: 76 NNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQ 135
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N L+ L L I+ +P F GL+ L L + +N + I AFR L + ++L
Sbjct: 136 NLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLAL 195
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N+I +P F + L+ L + N L + F GL ++ + ++ N L
Sbjct: 196 NKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYN-NLDEFPTAIR 254
Query: 285 NLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
L L+ L ++IR +PE+ F+ N L T+ N ++ + RS + +L +LTL+
Sbjct: 255 TLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNG 314
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
+ P+L LE+ + G ++
Sbjct: 315 ASQITEFPDLTGTAN-LESLTLTGAQI 340
Score = 50.8 bits (116), Expect = 8e-06
Identities = 40/137 (29%), Positives = 70/137 (51%), Gaps = 7/137 (5%)
Query: 163 FANTPPLKYLELSDA-KITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLS 221
F + P L+ L L+ A +IT PD G LE L + +I+++ L N+ VL
Sbjct: 301 FQHLPELRTLTLNGASQITEFPD--LTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLD 358
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEA 281
L+ N ++ LP+ F+ +L + + N + +TF+ L ++ + ++ N +
Sbjct: 359 LSYNLLEDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPN 416
Query: 282 VFSNLPALRTLQLDLSS 298
FS LP+L ++LDLSS
Sbjct: 417 AFSTLPSL--IKLDLSS 431
Score = 49.2 bits (112), Expect = 3e-05
Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 9/193 (4%)
Query: 103 FKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANM 162
+ N I + AF+ L + N +Q T D L L L + +L +
Sbjct: 289 YDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPD-LTGTANLESLTLTGAQISSLPQTV 347
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
P L+ L+LS + LP +F L+++++ NEI I F+ L ++ L+L
Sbjct: 348 CNQLPNLQVLDLSYNLLEDLP--SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNL 405
Query: 223 NKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAV 282
N+I + F++ P L+ L + N L S GL + +K++ N L+ +
Sbjct: 406 AWNKIAIIHPNAFSTLPSLIKLDLSSN---LLSSFPITGLHGLTHLKLTGN--HALQSLI 460
Query: 283 FS-NLPALRTLQL 294
S N P L+ +++
Sbjct: 461 SSENFPELKVIEM 473
>BC034389-1|AAH34389.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein 1 protein.
Length = 347
Score = 86.6 bits (205), Expect = 1e-16
Identities = 56/201 (27%), Positives = 96/201 (47%), Gaps = 1/201 (0%)
Query: 171 YLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
+L + +T LP + G + L++L++ N + +++ R + + VL L +N + L
Sbjct: 72 HLAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGL 131
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
P+GLF ++ L L + N L+ GL + + +S N L + +N LR
Sbjct: 132 PSGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLR 191
Query: 291 TLQLDLSSIRELPEEFISNS-PLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAEL 349
TL L + + LP + + L L L N+L+VL + +L Q L L L+ N +A +
Sbjct: 192 TLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARV 251
Query: 350 APELFADLRALETFVMDGNEL 370
A F LR L+ + N L
Sbjct: 252 AAGAFQGLRQLDMLDLSNNSL 272
Score = 65.7 bits (153), Expect = 3e-10
Identities = 51/199 (25%), Positives = 86/199 (43%), Gaps = 1/199 (0%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLN 191
T +P ++L+ KL L++ +L P L+ L+L+ +T LP F
Sbjct: 81 THLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASA 140
Query: 192 VLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
L+ L + EN++ + GL + L L+ NR++ LP GL A+ L L + N
Sbjct: 141 TLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQL 200
Query: 252 RYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI-RELPEEFISNS 310
L + RG ++ + + N L + + P LR L L+ + + R F
Sbjct: 201 ETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLR 260
Query: 311 PLRTLSLARNQLRVLPRSV 329
L L L+ N L +P +
Sbjct: 261 QLDMLDLSNNSLASVPEGL 279
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/144 (29%), Positives = 64/144 (44%), Gaps = 1/144 (0%)
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
LPA L +L L + N L E R + ++ + ++ N L +F L
Sbjct: 83 LPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASATL 142
Query: 290 RTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
TL L + + L ++ L L L+ N+LR LP +L T L +L L N +
Sbjct: 143 DTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLET 202
Query: 349 LAPELFADLRALETFVMDGNELQV 372
L P+L LE ++GN+LQV
Sbjct: 203 LPPDLLRGPLQLERLHLEGNKLQV 226
Score = 57.6 bits (133), Expect = 7e-08
Identities = 53/201 (26%), Positives = 85/201 (42%), Gaps = 4/201 (1%)
Query: 37 NLIVGARPRDYVNIDCMGGELVCAEFPEIDTPATTQLPSLSLRECSLPPLSCLLQKVHAE 96
NL+ GA +++ G E + EF QL L L +L L L + A
Sbjct: 86 NLLQGASKLQELHLSSNGLESLSPEFLR----PVPQLRVLDLTRNALTGLPSGLFQASAT 141
Query: 97 DVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNI 156
V+ +N + L GL + + +P +L + L L +
Sbjct: 142 LDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLE 201
Query: 157 TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHN 216
TL ++ L+ L L K+ VL D L L L + N++A + AGAF+GL
Sbjct: 202 TLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQ 261
Query: 217 VTVLSLNKNRIQALPAGLFAS 237
+ +L L+ N + ++P GL+AS
Sbjct: 262 LDMLDLSNNSLASVPEGLWAS 282
Score = 53.2 bits (122), Expect = 2e-06
Identities = 38/182 (20%), Positives = 77/182 (42%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L+ + + + ++ A T +P + ++ L L + L +
Sbjct: 102 NGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASATLDTLVLKENQLEVLEVSWLH 161
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L +L+LS ++ LP +L L++ EN++ + RG + L L
Sbjct: 162 GLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEG 221
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N++Q L L P L L + N + + F+GL + + +SNN ++ E +++
Sbjct: 222 NKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLASVPEGLWA 281
Query: 285 NL 286
+L
Sbjct: 282 SL 283
>BC013767-1|AAH13767.1| 601|Homo sapiens VASN protein protein.
Length = 601
Score = 86.6 bits (205), Expect = 1e-16
Identities = 72/211 (34%), Positives = 102/211 (48%), Gaps = 9/211 (4%)
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
A P L+ L+LS +I LP F L L L++ N + IT FRGL + L L
Sbjct: 1 AGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLG 60
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
KNRI+ + G F + RLL L + N R L L + + +S+N L L+ +
Sbjct: 61 KNRIRHIQPGAFDTLDRLLELKLQDNELRALPP---LRLPRLLLLDLSHNSLLALEPGIL 117
Query: 284 --SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTL 341
+N+ ALR L L + E + N L L ++ NQL +P V+RG LT L L
Sbjct: 118 DTANVEALRLAGLGLQQLDEGLFSRLRN--LHDLDVSDNQLERVP-PVIRGLRGLTRLRL 174
Query: 342 SYNA-VAELAPELFADLRALETFVMDGNELQ 371
+ N +A+L PE A L AL+ + LQ
Sbjct: 175 AGNTRIAQLRPEDLAGLAALQELDVSNLSLQ 205
Score = 62.9 bits (146), Expect = 2e-09
Identities = 62/223 (27%), Positives = 98/223 (43%), Gaps = 8/223 (3%)
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
LP L L+ + +L + +F L L+L+ ++ + ++ F GL LE+L + +N
Sbjct: 3 LPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKN 62
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG 261
I +I GAF L + L L N ++ALP PRLL L + NS L+
Sbjct: 63 RIRHIQPGAFDTLDRLLELKLQDNELRALPP---LRLPRLLLLDLSHNSLLALEPGIL-D 118
Query: 262 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARN- 320
+++ ++++ L E +FS L L L + + + +P L L LA N
Sbjct: 119 TANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLAGNT 178
Query: 321 ---QLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 360
QLR + L +L LS A+ LF LR L
Sbjct: 179 RIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLL 221
Score = 35.1 bits (77), Expect = 0.44
Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 2/95 (2%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN-EIANITAGAFRGLHN 216
L +F+ L L++SD ++ +P GL L +L + N IA + GL
Sbjct: 135 LDEGLFSRLRNLHDLDVSDNQLERVPP-VIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAA 193
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
+ L ++ +QALP L PRL L RN F
Sbjct: 194 LQELDVSNLSLQALPGDLSGLFPRLRLLAAARNPF 228
>AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-coupled
receptor HG38 protein.
Length = 907
Score = 86.6 bits (205), Expect = 1e-16
Identities = 61/230 (26%), Positives = 101/230 (43%), Gaps = 2/230 (0%)
Query: 139 LRSLPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
L SL L RL AG +T + F LK L L + ++ +P +A L L+ L
Sbjct: 86 LPSLRFLEELRL-AGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLR 144
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSE 257
+ N I+ + F GLH++ L L+ N + +P F S L +T+ N ++
Sbjct: 145 LDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDY 204
Query: 258 TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSL 317
F L + + + NN +L + F L +L TL L+ +++ E P + S L+ L
Sbjct: 205 AFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGF 264
Query: 318 ARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 367
N +R +P G L ++ N + + F L L T ++G
Sbjct: 265 HSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNG 314
Score = 86.2 bits (204), Expect = 2e-16
Identities = 71/267 (26%), Positives = 118/267 (44%), Gaps = 5/267 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + + +A + L + +A + VP L L H L+ + F
Sbjct: 124 NQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFR 183
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
+ L+ + L+ KI +PD AF L+ L L++ N I ++ F GLH++ L LN
Sbjct: 184 SLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNY 243
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N + P + + L L N+ R + + F G + I +N + + F
Sbjct: 244 NNLDEFPTAI-RTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQ 302
Query: 285 NLPALRTLQLD-LSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+LP LRTL L+ S I E P + + L +L+L Q+ LP++V L L LSY
Sbjct: 303 HLPELRTLTLNGASQITEFP-DLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSY 361
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
N + +L F+ + L+ + NE+
Sbjct: 362 NLLEDLPS--FSVCQKLQKIDLRHNEI 386
Score = 85.0 bits (201), Expect = 4e-16
Identities = 73/269 (27%), Positives = 124/269 (46%), Gaps = 5/269 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
NA+ + AF GL ++M VP + L++L L RL+A + + F+
Sbjct: 100 NALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFS 159
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L++L L D +T +P AF L+ L+ + + N+I +I AF L ++ VL L+
Sbjct: 160 GLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHN 219
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRI +L F L L + N+ + R L +++E+ +N ++ E F
Sbjct: 220 NRIHSLGKKCFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELGFHSNNIRSIPEKAFV 278
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSP-LRTLSL-ARNQLRVLPRSVLRGQTQLTSLTLS 342
P+L T+ + I+ + + P LRTL+L +Q+ P L G L SLTL+
Sbjct: 279 GNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPD--LTGTANLESLTLT 336
Query: 343 YNAVAELAPELFADLRALETFVMDGNELQ 371
++ L + L L+ + N L+
Sbjct: 337 GAQISSLPQTVCNQLPNLQVLDLSYNLLE 365
Score = 82.6 bits (195), Expect = 2e-15
Identities = 56/202 (27%), Positives = 94/202 (46%), Gaps = 2/202 (0%)
Query: 171 YLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
YL+LS I+ L + L LE+L + N + I GAF GL+++ VL L N+++ +
Sbjct: 70 YLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHV 129
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
P + L +L + N Y+ F GL ++ + + +N + F +L AL+
Sbjct: 130 PTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQ 189
Query: 291 TLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAEL 349
+ L L+ I +P+ N S L L L N++ L + G L +L L+YN + E
Sbjct: 190 AMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF 249
Query: 350 APELFADLRALETFVMDGNELQ 371
P L L+ N ++
Sbjct: 250 -PTAIRTLSNLKELGFHSNNIR 270
Score = 72.9 bits (171), Expect = 2e-12
Identities = 64/267 (23%), Positives = 111/267 (41%), Gaps = 3/267 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I+ L + L + A T +P L L L + +
Sbjct: 76 NNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQ 135
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N L+ L L I+ +P F GL+ L L + +N + I AFR L + ++L
Sbjct: 136 NLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLAL 195
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N+I +P F + L+ L + N L + F GL ++ + ++ N L
Sbjct: 196 NKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYN-NLDEFPTAIR 254
Query: 285 NLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
L L+ L ++IR +PE+ F+ N L T+ N ++ + RS + +L +LTL+
Sbjct: 255 TLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNG 314
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
+ P+L LE+ + G ++
Sbjct: 315 ASQITEFPDLTGTAN-LESLTLTGAQI 340
Score = 50.8 bits (116), Expect = 8e-06
Identities = 40/137 (29%), Positives = 70/137 (51%), Gaps = 7/137 (5%)
Query: 163 FANTPPLKYLELSDA-KITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLS 221
F + P L+ L L+ A +IT PD G LE L + +I+++ L N+ VL
Sbjct: 301 FQHLPELRTLTLNGASQITEFPD--LTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLD 358
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEA 281
L+ N ++ LP+ F+ +L + + N + +TF+ L ++ + ++ N +
Sbjct: 359 LSYNLLEDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPN 416
Query: 282 VFSNLPALRTLQLDLSS 298
FS LP+L ++LDLSS
Sbjct: 417 AFSTLPSL--IKLDLSS 431
Score = 49.2 bits (112), Expect = 3e-05
Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 9/193 (4%)
Query: 103 FKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANM 162
+ N I + AF+ L + N +Q T D L L L + +L +
Sbjct: 289 YDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPD-LTGTANLESLTLTGAQISSLPQTV 347
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
P L+ L+LS + LP +F L+++++ NEI I F+ L ++ L+L
Sbjct: 348 CNQLPNLQVLDLSYNLLEDLP--SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNL 405
Query: 223 NKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAV 282
N+I + F++ P L+ L + N L S GL + +K++ N L+ +
Sbjct: 406 AWNKIAIIHPNAFSTLPSLIKLDLSSN---LLSSFPITGLHGLTHLKLTGN--HALQSLI 460
Query: 283 FS-NLPALRTLQL 294
S N P L+ +++
Sbjct: 461 SSENFPELKVIEM 473
>AB073607-1|BAD38644.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein protein.
Length = 347
Score = 86.6 bits (205), Expect = 1e-16
Identities = 56/201 (27%), Positives = 96/201 (47%), Gaps = 1/201 (0%)
Query: 171 YLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
+L + +T LP + G + L++L++ N + +++ R + + VL L +N + L
Sbjct: 72 HLAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGL 131
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
P+GLF ++ L L + N L+ GL + + +S N L + +N LR
Sbjct: 132 PSGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLR 191
Query: 291 TLQLDLSSIRELPEEFISNS-PLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAEL 349
TL L + + LP + + L L L N+L+VL + +L Q L L L+ N +A +
Sbjct: 192 TLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARV 251
Query: 350 APELFADLRALETFVMDGNEL 370
A F LR L+ + N L
Sbjct: 252 AAGAFQGLRQLDMLDLSNNSL 272
Score = 65.7 bits (153), Expect = 3e-10
Identities = 51/199 (25%), Positives = 86/199 (43%), Gaps = 1/199 (0%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLN 191
T +P ++L+ KL L++ +L P L+ L+L+ +T LP F
Sbjct: 81 THLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASA 140
Query: 192 VLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
L+ L + EN++ + GL + L L+ NR++ LP GL A+ L L + N
Sbjct: 141 TLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQL 200
Query: 252 RYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI-RELPEEFISNS 310
L + RG ++ + + N L + + P LR L L+ + + R F
Sbjct: 201 ETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLR 260
Query: 311 PLRTLSLARNQLRVLPRSV 329
L L L+ N L +P +
Sbjct: 261 QLDMLDLSNNSLASVPEGL 279
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/144 (29%), Positives = 64/144 (44%), Gaps = 1/144 (0%)
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
LPA L +L L + N L E R + ++ + ++ N L +F L
Sbjct: 83 LPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASATL 142
Query: 290 RTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
TL L + + L ++ L L L+ N+LR LP +L T L +L L N +
Sbjct: 143 DTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLET 202
Query: 349 LAPELFADLRALETFVMDGNELQV 372
L P+L LE ++GN+LQV
Sbjct: 203 LPPDLLRGPLQLERLHLEGNKLQV 226
Score = 57.6 bits (133), Expect = 7e-08
Identities = 53/201 (26%), Positives = 85/201 (42%), Gaps = 4/201 (1%)
Query: 37 NLIVGARPRDYVNIDCMGGELVCAEFPEIDTPATTQLPSLSLRECSLPPLSCLLQKVHAE 96
NL+ GA +++ G E + EF QL L L +L L L + A
Sbjct: 86 NLLQGASKLQELHLSSNGLESLSPEFLR----PVPQLRVLDLTRNALTGLPSGLFQASAT 141
Query: 97 DVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNI 156
V+ +N + L GL + + +P +L + L L +
Sbjct: 142 LDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLE 201
Query: 157 TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHN 216
TL ++ L+ L L K+ VL D L L L + N++A + AGAF+GL
Sbjct: 202 TLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQ 261
Query: 217 VTVLSLNKNRIQALPAGLFAS 237
+ +L L+ N + ++P GL+AS
Sbjct: 262 LDMLDLSNNSLASVPEGLWAS 282
Score = 53.2 bits (122), Expect = 2e-06
Identities = 38/182 (20%), Positives = 77/182 (42%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L+ + + + ++ A T +P + ++ L L + L +
Sbjct: 102 NGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASATLDTLVLKENQLEVLEVSWLH 161
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L +L+LS ++ LP +L L++ EN++ + RG + L L
Sbjct: 162 GLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEG 221
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N++Q L L P L L + N + + F+GL + + +SNN ++ E +++
Sbjct: 222 NKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLASVPEGLWA 281
Query: 285 NL 286
+L
Sbjct: 282 SL 283
>AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein.
Length = 622
Score = 86.2 bits (204), Expect = 2e-16
Identities = 62/234 (26%), Positives = 111/234 (47%), Gaps = 2/234 (0%)
Query: 140 RSLPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
++ P+ T F G NI+ ++ + L L L ++ I + AF+ L L L +
Sbjct: 56 KNFPESTVFLYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFL 115
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET 258
N I + G F+GL N+ L L N++ +P G+F + L + RN L S T
Sbjct: 116 NNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGT 175
Query: 259 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSL 317
F G+ ++ + +SNN L + E+ F +L L L L +++ ++P F LR LSL
Sbjct: 176 FVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSL 235
Query: 318 ARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
+ N + + +G L L L + + + + F+ + L+ ++ N+L+
Sbjct: 236 SHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLE 289
Score = 77.8 bits (183), Expect = 6e-14
Identities = 63/242 (26%), Positives = 106/242 (43%), Gaps = 2/242 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I L+ FKGL + + VP V L + + L R L + F
Sbjct: 118 NFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFV 177
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L+LS+ I + + F L L L + N + + + AF L ++ LSL+
Sbjct: 178 GMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSH 237
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N I+A+ F L L + + R + + F G+++++ + +S+N L FS
Sbjct: 238 NPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFS 297
Query: 285 NLPALRTLQLDLSSIRELPEEFISN--SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS 342
L L L+LD + I + + N + L+ L+L+ N L L VL+ + L L +
Sbjct: 298 LLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQAN 357
Query: 343 YN 344
N
Sbjct: 358 SN 359
Score = 72.1 bits (169), Expect = 3e-12
Identities = 59/233 (25%), Positives = 102/233 (43%), Gaps = 1/233 (0%)
Query: 139 LRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
L L L L+ + ++ F L +L L++ I L F GL L L +
Sbjct: 80 LTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYL 139
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET 258
N+++ + G F L +V L+L +NR+ L +G F L L + N+ +
Sbjct: 140 QYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESG 199
Query: 259 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSL 317
F+ L+++ + + +N + F L +LR L L + I + P F + L L L
Sbjct: 200 FQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLL 259
Query: 318 ARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+++R + R G L L LS+N + L + F+ L+ L +D N +
Sbjct: 260 KNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRI 312
>AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein.
Length = 622
Score = 86.2 bits (204), Expect = 2e-16
Identities = 62/234 (26%), Positives = 111/234 (47%), Gaps = 2/234 (0%)
Query: 140 RSLPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
++ P+ T F G NI+ ++ + L L L ++ I + AF+ L L L +
Sbjct: 56 KNFPESTVFLYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFL 115
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET 258
N I + G F+GL N+ L L N++ +P G+F + L + RN L S T
Sbjct: 116 NNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGT 175
Query: 259 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSL 317
F G+ ++ + +SNN L + E+ F +L L L L +++ ++P F LR LSL
Sbjct: 176 FVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSL 235
Query: 318 ARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
+ N + + +G L L L + + + + F+ + L+ ++ N+L+
Sbjct: 236 SHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLE 289
Score = 77.8 bits (183), Expect = 6e-14
Identities = 63/242 (26%), Positives = 106/242 (43%), Gaps = 2/242 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I L+ FKGL + + VP V L + + L R L + F
Sbjct: 118 NFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFV 177
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L+LS+ I + + F L L L + N + + + AF L ++ LSL+
Sbjct: 178 GMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSH 237
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N I+A+ F L L + + R + + F G+++++ + +S+N L FS
Sbjct: 238 NPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFS 297
Query: 285 NLPALRTLQLDLSSIRELPEEFISN--SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS 342
L L L+LD + I + + N + L+ L+L+ N L L VL+ + L L +
Sbjct: 298 LLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQAN 357
Query: 343 YN 344
N
Sbjct: 358 SN 359
Score = 72.1 bits (169), Expect = 3e-12
Identities = 59/233 (25%), Positives = 102/233 (43%), Gaps = 1/233 (0%)
Query: 139 LRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
L L L L+ + ++ F L +L L++ I L F GL L L +
Sbjct: 80 LTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYL 139
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET 258
N+++ + G F L +V L+L +NR+ L +G F L L + N+ +
Sbjct: 140 QYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESG 199
Query: 259 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSL 317
F+ L+++ + + +N + F L +LR L L + I + P F + L L L
Sbjct: 200 FQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLL 259
Query: 318 ARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+++R + R G L L LS+N + L + F+ L+ L +D N +
Sbjct: 260 KNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRI 312
>AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens
cDNA FLJ41026 fis, clone BRAMY2004771, weakly similar
to CHONDROADHERIN PRECURSOR. ).
Length = 622
Score = 86.2 bits (204), Expect = 2e-16
Identities = 62/234 (26%), Positives = 111/234 (47%), Gaps = 2/234 (0%)
Query: 140 RSLPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
++ P+ T F G NI+ ++ + L L L ++ I + AF+ L L L +
Sbjct: 56 KNFPESTVFLYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFL 115
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET 258
N I + G F+GL N+ L L N++ +P G+F + L + RN L S T
Sbjct: 116 NNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGT 175
Query: 259 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSL 317
F G+ ++ + +SNN L + E+ F +L L L L +++ ++P F LR LSL
Sbjct: 176 FVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSL 235
Query: 318 ARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
+ N + + +G L L L + + + + F+ + L+ ++ N+L+
Sbjct: 236 SHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLE 289
Score = 77.8 bits (183), Expect = 6e-14
Identities = 63/242 (26%), Positives = 106/242 (43%), Gaps = 2/242 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I L+ FKGL + + VP V L + + L R L + F
Sbjct: 118 NFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFV 177
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L+LS+ I + + F L L L + N + + + AF L ++ LSL+
Sbjct: 178 GMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSH 237
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N I+A+ F L L + + R + + F G+++++ + +S+N L FS
Sbjct: 238 NPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFS 297
Query: 285 NLPALRTLQLDLSSIRELPEEFISN--SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS 342
L L L+LD + I + + N + L+ L+L+ N L L VL+ + L L +
Sbjct: 298 LLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQAN 357
Query: 343 YN 344
N
Sbjct: 358 SN 359
Score = 72.1 bits (169), Expect = 3e-12
Identities = 59/233 (25%), Positives = 102/233 (43%), Gaps = 1/233 (0%)
Query: 139 LRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
L L L L+ + ++ F L +L L++ I L F GL L L +
Sbjct: 80 LTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYL 139
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET 258
N+++ + G F L +V L+L +NR+ L +G F L L + N+ +
Sbjct: 140 QYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESG 199
Query: 259 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSL 317
F+ L+++ + + +N + F L +LR L L + I + P F + L L L
Sbjct: 200 FQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLL 259
Query: 318 ARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+++R + R G L L LS+N + L + F+ L+ L +D N +
Sbjct: 260 KNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRI 312
>BC070198-1|AAH70198.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein 1 protein.
Length = 347
Score = 85.8 bits (203), Expect = 2e-16
Identities = 56/201 (27%), Positives = 95/201 (47%), Gaps = 1/201 (0%)
Query: 171 YLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
+L + +T LP + G + L++L++ N + +++ R + + VL L +N + L
Sbjct: 72 HLAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGL 131
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
P GLF ++ L L + N L+ GL + + +S N L + +N LR
Sbjct: 132 PPGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLR 191
Query: 291 TLQLDLSSIRELPEEFISNS-PLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAEL 349
TL L + + LP + + L L L N+L+VL + +L Q L L L+ N +A +
Sbjct: 192 TLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARV 251
Query: 350 APELFADLRALETFVMDGNEL 370
A F LR L+ + N L
Sbjct: 252 AAGAFQGLRQLDMLDLSNNSL 272
Score = 65.3 bits (152), Expect = 4e-10
Identities = 51/199 (25%), Positives = 86/199 (43%), Gaps = 1/199 (0%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLN 191
T +P ++L+ KL L++ +L P L+ L+L+ +T LP F
Sbjct: 81 THLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASA 140
Query: 192 VLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
L+ L + EN++ + GL + L L+ NR++ LP GL A+ L L + N
Sbjct: 141 TLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQL 200
Query: 252 RYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI-RELPEEFISNS 310
L + RG ++ + + N L + + P LR L L+ + + R F
Sbjct: 201 ETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLR 260
Query: 311 PLRTLSLARNQLRVLPRSV 329
L L L+ N L +P +
Sbjct: 261 QLDMLDLSNNSLASVPEGL 279
Score = 58.8 bits (136), Expect = 3e-08
Identities = 42/144 (29%), Positives = 64/144 (44%), Gaps = 1/144 (0%)
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
LPA L +L L + N L E R + ++ + ++ N L +F L
Sbjct: 83 LPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATL 142
Query: 290 RTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
TL L + + L ++ L L L+ N+LR LP +L T L +L L N +
Sbjct: 143 DTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLET 202
Query: 349 LAPELFADLRALETFVMDGNELQV 372
L P+L LE ++GN+LQV
Sbjct: 203 LPPDLLRGPLQLERLHLEGNKLQV 226
Score = 56.8 bits (131), Expect = 1e-07
Identities = 53/201 (26%), Positives = 85/201 (42%), Gaps = 4/201 (1%)
Query: 37 NLIVGARPRDYVNIDCMGGELVCAEFPEIDTPATTQLPSLSLRECSLPPLSCLLQKVHAE 96
NL+ GA +++ G E + EF QL L L +L L L + A
Sbjct: 86 NLLQGASKLQELHLSSNGLESLSPEFLR----PVPQLRVLDLTRNALTGLPPGLFQASAT 141
Query: 97 DVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNI 156
V+ +N + L GL + + +P +L + L L +
Sbjct: 142 LDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLE 201
Query: 157 TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHN 216
TL ++ L+ L L K+ VL D L L L + N++A + AGAF+GL
Sbjct: 202 TLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQ 261
Query: 217 VTVLSLNKNRIQALPAGLFAS 237
+ +L L+ N + ++P GL+AS
Sbjct: 262 LDMLDLSNNSLASVPEGLWAS 282
Score = 53.2 bits (122), Expect = 2e-06
Identities = 38/182 (20%), Positives = 77/182 (42%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L+ + + + ++ A T +P + ++ L L + L +
Sbjct: 102 NGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQLEVLEVSWLH 161
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L +L+LS ++ LP +L L++ EN++ + RG + L L
Sbjct: 162 GLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEG 221
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N++Q L L P L L + N + + F+GL + + +SNN ++ E +++
Sbjct: 222 NKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLASVPEGLWA 281
Query: 285 NL 286
+L
Sbjct: 282 SL 283
>AF403428-1|AAK95527.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein protein.
Length = 347
Score = 85.8 bits (203), Expect = 2e-16
Identities = 56/201 (27%), Positives = 95/201 (47%), Gaps = 1/201 (0%)
Query: 171 YLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
+L + +T LP + G + L++L++ N + +++ R + + VL L +N + L
Sbjct: 72 HLAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGL 131
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
P GLF ++ L L + N L+ GL + + +S N L + +N LR
Sbjct: 132 PPGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLR 191
Query: 291 TLQLDLSSIRELPEEFISNS-PLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAEL 349
TL L + + LP + + L L L N+L+VL + +L Q L L L+ N +A +
Sbjct: 192 TLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARV 251
Query: 350 APELFADLRALETFVMDGNEL 370
A F LR L+ + N L
Sbjct: 252 AAGAFQGLRQLDMLDLSNNSL 272
Score = 65.3 bits (152), Expect = 4e-10
Identities = 51/199 (25%), Positives = 86/199 (43%), Gaps = 1/199 (0%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLN 191
T +P ++L+ KL L++ +L P L+ L+L+ +T LP F
Sbjct: 81 THLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASA 140
Query: 192 VLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
L+ L + EN++ + GL + L L+ NR++ LP GL A+ L L + N
Sbjct: 141 TLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQL 200
Query: 252 RYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI-RELPEEFISNS 310
L + RG ++ + + N L + + P LR L L+ + + R F
Sbjct: 201 ETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLR 260
Query: 311 PLRTLSLARNQLRVLPRSV 329
L L L+ N L +P +
Sbjct: 261 QLDMLDLSNNSLASVPEGL 279
Score = 58.8 bits (136), Expect = 3e-08
Identities = 42/144 (29%), Positives = 64/144 (44%), Gaps = 1/144 (0%)
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
LPA L +L L + N L E R + ++ + ++ N L +F L
Sbjct: 83 LPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATL 142
Query: 290 RTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
TL L + + L ++ L L L+ N+LR LP +L T L +L L N +
Sbjct: 143 DTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLET 202
Query: 349 LAPELFADLRALETFVMDGNELQV 372
L P+L LE ++GN+LQV
Sbjct: 203 LPPDLLRGPLQLERLHLEGNKLQV 226
Score = 56.8 bits (131), Expect = 1e-07
Identities = 53/201 (26%), Positives = 85/201 (42%), Gaps = 4/201 (1%)
Query: 37 NLIVGARPRDYVNIDCMGGELVCAEFPEIDTPATTQLPSLSLRECSLPPLSCLLQKVHAE 96
NL+ GA +++ G E + EF QL L L +L L L + A
Sbjct: 86 NLLQGASKLQELHLSSNGLESLSPEFLR----PVPQLRVLDLTRNALTGLPPGLFQASAT 141
Query: 97 DVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNI 156
V+ +N + L GL + + +P +L + L L +
Sbjct: 142 LDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLE 201
Query: 157 TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHN 216
TL ++ L+ L L K+ VL D L L L + N++A + AGAF+GL
Sbjct: 202 TLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQ 261
Query: 217 VTVLSLNKNRIQALPAGLFAS 237
+ +L L+ N + ++P GL+AS
Sbjct: 262 LDMLDLSNNSLASVPEGLWAS 282
Score = 53.2 bits (122), Expect = 2e-06
Identities = 38/182 (20%), Positives = 77/182 (42%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L+ + + + ++ A T +P + ++ L L + L +
Sbjct: 102 NGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQLEVLEVSWLH 161
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L +L+LS ++ LP +L L++ EN++ + RG + L L
Sbjct: 162 GLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEG 221
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N++Q L L P L L + N + + F+GL + + +SNN ++ E +++
Sbjct: 222 NKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLASVPEGLWA 281
Query: 285 NL 286
+L
Sbjct: 282 SL 283
>BC131897-1|AAI31898.1| 420|Homo sapiens LRRC4B protein protein.
Length = 420
Score = 85.4 bits (202), Expect = 3e-16
Identities = 58/202 (28%), Positives = 94/202 (46%), Gaps = 2/202 (0%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+YL L + I V+ D F L LE L + +N + I GAF GL ++ L L NR+
Sbjct: 89 RYLNLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTT 148
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPA 288
+P F +L L + N + S F + ++ + + L + EA F L
Sbjct: 149 VPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVN 208
Query: 289 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
LR L L + +++++P + L L L+ N+L ++ +G T L L L + VA
Sbjct: 209 LRYLNLGMCNLKDIP-NLTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVAT 267
Query: 349 LAPELFADLRALETFVMDGNEL 370
+ F DL++LE + N L
Sbjct: 268 IERNAFDDLKSLEELNLSHNNL 289
Score = 68.9 bits (161), Expect = 3e-11
Identities = 67/239 (28%), Positives = 107/239 (44%), Gaps = 13/239 (5%)
Query: 137 DVLRSLPKLTHFRLNAGRN--ITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLE 194
+V S+P T + LN N + + F + L+ L+LS + + AF GL L
Sbjct: 79 EVPASIPVNTRY-LNLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLN 137
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMR-NSFRY 253
L +++N + + AF L + L L N I+++P+ F P L L + Y
Sbjct: 138 TLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEY 197
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL-RTLQLDLSSIR-EL--PEEFISN 309
+ F GL +++ + + LK+ NL AL R +L+LS R +L P F
Sbjct: 198 ISEAAFEGLVNLRYLNLGM---CNLKD--IPNLTALVRLEELELSGNRLDLIRPGSFQGL 252
Query: 310 SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
+ LR L L Q+ + R+ L L LS+N + L +LF L LE ++ N
Sbjct: 253 TSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHN 311
Score = 44.8 bits (101), Expect = 5e-04
Identities = 47/194 (24%), Positives = 80/194 (41%), Gaps = 25/194 (12%)
Query: 104 KNAINPLNADAFKGL-GITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANM 162
KN + + AF GL + L +F+ TTVP L KL L ++ +
Sbjct: 119 KNLVRKIEVGAFNGLPSLNTLELFD-NRLTTVPTQAFEYLSKLRELWLRNNPIESIPSYA 177
Query: 163 FANTPPLKYLELSDAK-ITVLPDDAFLGLNVLEQLNVWE---NEIANITA---------- 208
F P L+ L+L + K + + + AF GL L LN+ +I N+TA
Sbjct: 178 FNRVPSLRRLDLGELKRLEYISEAAFEGLVNLRYLNLGMCNLKDIPNLTALVRLEELELS 237
Query: 209 ---------GAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
G+F+GL ++ L L ++ + F L L + N+ L + F
Sbjct: 238 GNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLF 297
Query: 260 RGLDHIQEIKISNN 273
L ++ + +++N
Sbjct: 298 TPLHRLERVHLNHN 311
>BC032460-1|AAH32460.1| 634|Homo sapiens Unknown (protein for
IMAGE:5200456) protein.
Length = 634
Score = 85.4 bits (202), Expect = 3e-16
Identities = 58/202 (28%), Positives = 94/202 (46%), Gaps = 2/202 (0%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+YL L + I V+ D F L LE L + +N + I GAF GL ++ L L NR+
Sbjct: 89 RYLNLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTT 148
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPA 288
+P F +L L + N + S F + ++ + + L + EA F L
Sbjct: 149 VPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVN 208
Query: 289 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
LR L L + +++++P + L L L+ N+L ++ +G T L L L + VA
Sbjct: 209 LRYLNLGMCNLKDIP-NLTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVAT 267
Query: 349 LAPELFADLRALETFVMDGNEL 370
+ F DL++LE + N L
Sbjct: 268 IERNAFDDLKSLEELNLSHNNL 289
Score = 68.9 bits (161), Expect = 3e-11
Identities = 67/239 (28%), Positives = 107/239 (44%), Gaps = 13/239 (5%)
Query: 137 DVLRSLPKLTHFRLNAGRN--ITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLE 194
+V S+P T + LN N + + F + L+ L+LS + + AF GL L
Sbjct: 79 EVPASIPVNTRY-LNLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLN 137
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMR-NSFRY 253
L +++N + + AF L + L L N I+++P+ F P L L + Y
Sbjct: 138 TLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEY 197
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL-RTLQLDLSSIR-EL--PEEFISN 309
+ F GL +++ + + LK+ NL AL R +L+LS R +L P F
Sbjct: 198 ISEAAFEGLVNLRYLNLGM---CNLKD--IPNLTALVRLEELELSGNRLDLIRPGSFQGL 252
Query: 310 SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
+ LR L L Q+ + R+ L L LS+N + L +LF L LE ++ N
Sbjct: 253 TSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHN 311
Score = 44.8 bits (101), Expect = 5e-04
Identities = 47/194 (24%), Positives = 80/194 (41%), Gaps = 25/194 (12%)
Query: 104 KNAINPLNADAFKGL-GITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANM 162
KN + + AF GL + L +F+ TTVP L KL L ++ +
Sbjct: 119 KNLVRKIEVGAFNGLPSLNTLELFD-NRLTTVPTQAFEYLSKLRELWLRNNPIESIPSYA 177
Query: 163 FANTPPLKYLELSDAK-ITVLPDDAFLGLNVLEQLNVWE---NEIANITA---------- 208
F P L+ L+L + K + + + AF GL L LN+ +I N+TA
Sbjct: 178 FNRVPSLRRLDLGELKRLEYISEAAFEGLVNLRYLNLGMCNLKDIPNLTALVRLEELELS 237
Query: 209 ---------GAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
G+F+GL ++ L L ++ + F L L + N+ L + F
Sbjct: 238 GNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLF 297
Query: 260 RGLDHIQEIKISNN 273
L ++ + +++N
Sbjct: 298 TPLHRLERVHLNHN 311
>AC108017-1|AAY41039.1| 260|Homo sapiens unknown protein.
Length = 260
Score = 85.4 bits (202), Expect = 3e-16
Identities = 60/184 (32%), Positives = 93/184 (50%), Gaps = 2/184 (1%)
Query: 179 ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFAST 238
I LP D F + L++L + N+I +I+ AFRGL+++T L L+ NRI L G+F
Sbjct: 75 IRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDL 134
Query: 239 PRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKE-AVFSNLPALRTLQLDLS 297
RL L + N + TF GL+ + + + NNV L + + ++P L L L+ +
Sbjct: 135 HRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGN 194
Query: 298 SIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFAD 356
I L FIS S L L + +N++ L + +L L L N + L P +F D
Sbjct: 195 HIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKD 254
Query: 357 LRAL 360
L+ L
Sbjct: 255 LKEL 258
Score = 56.4 bits (130), Expect = 2e-07
Identities = 47/182 (25%), Positives = 75/182 (41%), Gaps = 2/182 (1%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L + F N L+ L L + KIT + AF GLN L +L + N I + G F LH +
Sbjct: 78 LPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRL 137
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF-RYLDSETFRGLDHIQEIKISNNVPL 276
L + N + + F L+ L +M N R D + + + + + N
Sbjct: 138 EWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIH 197
Query: 277 TLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
L+ F + L L + + I L E F L L L N++ LP + + +
Sbjct: 198 NLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKE 257
Query: 336 LT 337
L+
Sbjct: 258 LS 259
Score = 54.8 bits (126), Expect = 5e-07
Identities = 45/157 (28%), Positives = 70/157 (44%), Gaps = 2/157 (1%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
NVT +SL N I+ LP F + L L + N + FRGL+ + ++ +S+N
Sbjct: 64 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 123
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLP-RSVLRGQ 333
LK VF +L L L ++ + + + P F + L L L N L LP + + +
Sbjct: 124 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 183
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+L L L N + L F L VM N++
Sbjct: 184 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKI 220
Score = 54.4 bits (125), Expect = 7e-07
Identities = 47/171 (27%), Positives = 73/171 (42%), Gaps = 1/171 (0%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
+P D ++ L L + ++ F L L LS +IT L F L+ L
Sbjct: 78 LPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRL 137
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP-AGLFASTPRLLNLTMMRNSFR 252
E L + +N ++ I+ F GL+++ +L L N + LP L PRL L + N
Sbjct: 138 EWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIH 197
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP 303
L + TF ++ + + N L E F+ L L L L + I LP
Sbjct: 198 NLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLP 248
Score = 47.2 bits (107), Expect = 1e-04
Identities = 57/241 (23%), Positives = 94/241 (39%), Gaps = 5/241 (2%)
Query: 29 YQCSRPSTNLIVGARPRDYVNIDCMGGELVCAEFPEIDTPA-TTQLPSLSLRECSLPPLS 87
Y + +VG+ P V C G EL C E P+ ++ + ++SL+ + L
Sbjct: 23 YPFEAETPECLVGSVP---VQCLCQGLELDCDETNLRAVPSVSSNVTAMSLQWNLIRKLP 79
Query: 88 CLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTH 147
K + + K + N I ++ AF+GL + + T + V L +L
Sbjct: 80 PDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEW 139
Query: 148 FRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLG-LNVLEQLNVWENEIANI 206
+ + F L L L + +T LPD + L L++ N I N+
Sbjct: 140 LIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNL 199
Query: 207 TAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQ 266
F N+TVL + KN+I L FA +L L + N L F+ L +
Sbjct: 200 RNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELS 259
Query: 267 E 267
+
Sbjct: 260 Q 260
>AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled receptor
LGR5 protein.
Length = 907
Score = 84.6 bits (200), Expect = 5e-16
Identities = 61/230 (26%), Positives = 100/230 (43%), Gaps = 2/230 (0%)
Query: 139 LRSLPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
L SL L RL AG +T + F LK L L + ++ +P +A L L+ L
Sbjct: 86 LPSLHFLEELRL-AGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLR 144
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSE 257
+ N I+ + F GLH++ L L+ N + +P F S L +T+ N ++
Sbjct: 145 LDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDY 204
Query: 258 TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSL 317
F L + + NN +L + F L +L TL L+ +++ E P + S L+ L
Sbjct: 205 AFGNLSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGF 264
Query: 318 ARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 367
N +R +P G L ++ N + + F L L T ++G
Sbjct: 265 HSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNG 314
Score = 83.8 bits (198), Expect = 9e-16
Identities = 70/267 (26%), Positives = 117/267 (43%), Gaps = 5/267 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + + +A + L + +A + VP L L H L+ + F
Sbjct: 124 NQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFR 183
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
+ L+ + L+ KI +PD AF L+ L++ N I ++ F GLH++ L LN
Sbjct: 184 SLSALQAMTLALNKIHHIPDYAFGNLSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLNY 243
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N + P + + L L N+ R + + F G + I +N + + F
Sbjct: 244 NNLDEFPTAI-RTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQ 302
Query: 285 NLPALRTLQLD-LSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+LP LRTL L+ S I E P + + L +L+L Q+ LP++V L L LSY
Sbjct: 303 HLPELRTLTLNGASQITEFP-DLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSY 361
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
N + +L F+ + L+ + NE+
Sbjct: 362 NLLEDLPS--FSVCQKLQKIDLRHNEI 386
Score = 83.4 bits (197), Expect = 1e-15
Identities = 73/269 (27%), Positives = 123/269 (45%), Gaps = 5/269 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
NA+ + AF GL ++M VP + L++L L RL+A + + F+
Sbjct: 100 NALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFS 159
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L++L L D +T +P AF L+ L+ + + N+I +I AF L + VL L+
Sbjct: 160 GLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSWVVLHLHN 219
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRI +L F L L + N+ + R L +++E+ +N ++ E F
Sbjct: 220 NRIHSLGKKCFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELGFHSNNIRSIPEKAFV 278
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSP-LRTLSL-ARNQLRVLPRSVLRGQTQLTSLTLS 342
P+L T+ + I+ + + P LRTL+L +Q+ P L G L SLTL+
Sbjct: 279 GNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPD--LTGTANLESLTLT 336
Query: 343 YNAVAELAPELFADLRALETFVMDGNELQ 371
++ L + L L+ + N L+
Sbjct: 337 GAQISSLPQTVCNQLPNLQVLDLSYNLLE 365
Score = 80.6 bits (190), Expect = 9e-15
Identities = 55/202 (27%), Positives = 94/202 (46%), Gaps = 2/202 (0%)
Query: 171 YLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
YL+LS I+ L + L+ LE+L + N + I GAF GL+++ VL L N+++ +
Sbjct: 70 YLDLSMNNISQLLPNPLPSLHFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHV 129
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
P + L +L + N Y+ F GL ++ + + +N + F +L AL+
Sbjct: 130 PTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQ 189
Query: 291 TLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAEL 349
+ L L+ I +P+ N S L L N++ L + G L +L L+YN + E
Sbjct: 190 AMTLALNKIHHIPDYAFGNLSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF 249
Query: 350 APELFADLRALETFVMDGNELQ 371
P L L+ N ++
Sbjct: 250 -PTAIRTLSNLKELGFHSNNIR 270
Score = 70.5 bits (165), Expect = 9e-12
Identities = 63/267 (23%), Positives = 110/267 (41%), Gaps = 3/267 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I+ L + L + A T +P L L L + +
Sbjct: 76 NNISQLLPNPLPSLHFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQ 135
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N L+ L L I+ +P F GL+ L L + +N + I AFR L + ++L
Sbjct: 136 NLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLAL 195
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N+I +P F + + L + N L + F GL ++ + ++ N L
Sbjct: 196 NKIHHIPDYAFGNLSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYN-NLDEFPTAIR 254
Query: 285 NLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
L L+ L ++IR +PE+ F+ N L T+ N ++ + RS + +L +LTL+
Sbjct: 255 TLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNG 314
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
+ P+L LE+ + G ++
Sbjct: 315 ASQITEFPDLTGTAN-LESLTLTGAQI 340
Score = 50.8 bits (116), Expect = 8e-06
Identities = 40/137 (29%), Positives = 70/137 (51%), Gaps = 7/137 (5%)
Query: 163 FANTPPLKYLELSDA-KITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLS 221
F + P L+ L L+ A +IT PD G LE L + +I+++ L N+ VL
Sbjct: 301 FQHLPELRTLTLNGASQITEFPD--LTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLD 358
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEA 281
L+ N ++ LP+ F+ +L + + N + +TF+ L ++ + ++ N +
Sbjct: 359 LSYNLLEDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPN 416
Query: 282 VFSNLPALRTLQLDLSS 298
FS LP+L ++LDLSS
Sbjct: 417 AFSTLPSL--IKLDLSS 431
Score = 49.2 bits (112), Expect = 3e-05
Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 9/193 (4%)
Query: 103 FKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANM 162
+ N I + AF+ L + N +Q T D L L L + +L +
Sbjct: 289 YDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPD-LTGTANLESLTLTGAQISSLPQTV 347
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
P L+ L+LS + LP +F L+++++ NEI I F+ L ++ L+L
Sbjct: 348 CNQLPNLQVLDLSYNLLEDLP--SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNL 405
Query: 223 NKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAV 282
N+I + F++ P L+ L + N L S GL + +K++ N L+ +
Sbjct: 406 AWNKIAIIHPNAFSTLPSLIKLDLSSN---LLSSFPITGLHGLTHLKLTGN--HALQSLI 460
Query: 283 FS-NLPALRTLQL 294
S N P L+ +++
Sbjct: 461 SSENFPELKVIEM 473
>BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 84.2 bits (199), Expect = 7e-16
Identities = 71/268 (26%), Positives = 113/268 (42%), Gaps = 3/268 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ + AF GL ++M +P + L LP L RL+A + F
Sbjct: 48 NHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFE 107
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L++L L D +T +P A L L+ + + N I++I AF+ L ++ VL L+
Sbjct: 108 GLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHN 167
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRIQ L F L L + N + R L +QE+ NN + E F
Sbjct: 168 NRIQHLGTHSFEGLHNLETLDLNYNKLQEF-PVAIRTLGRLQELGFHNNNIKAIPEKAFM 226
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
P L+T+ + I+ + P L TLSL + + L+G T L LTL+
Sbjct: 227 GNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSL-NGAMDIQEFPDLKGTTSLEILTLTR 285
Query: 344 NAVAELAPELFADLRALETFVMDGNELQ 371
+ L + L L + N+++
Sbjct: 286 AGIRLLPSGMCQQLPRLRVLELSHNQIE 313
Score = 83.0 bits (196), Expect = 2e-15
Identities = 54/200 (27%), Positives = 94/200 (47%), Gaps = 2/200 (1%)
Query: 173 ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
+LS +T L F L LE+L + N +++I AF GL+++ +L L N++ +PA
Sbjct: 20 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 79
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTL 292
P L +L + N + +F GL ++ + + +N + +NLPAL+ +
Sbjct: 80 EALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAM 139
Query: 293 QLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAP 351
L L+ I +P+ N + L L L N+++ L G L +L L+YN + E P
Sbjct: 140 TLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEF-P 198
Query: 352 ELFADLRALETFVMDGNELQ 371
L L+ N ++
Sbjct: 199 VAIRTLGRLQELGFHNNNIK 218
Score = 76.6 bits (180), Expect = 1e-13
Identities = 73/289 (25%), Positives = 120/289 (41%), Gaps = 25/289 (8%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I+ + +F+GL + + A T +PV L +LP L L R + F
Sbjct: 96 NLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQ 155
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N L L L + +I L +F GL+ LE L++ N++ A R L + L +
Sbjct: 156 NLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPV-AIRTLGRLQELGFHN 214
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP--------- 275
N I+A+P F P L + N +++ F+ L + + ++ +
Sbjct: 215 NNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKG 274
Query: 276 ------LTLKEA--------VFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 321
LTL A + LP LR L+L + I ELP L + L N+
Sbjct: 275 TTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHRCQK-LEEIGLQHNR 333
Query: 322 LRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ + + L +L LS+NA+ + PE F+ L +L + N+L
Sbjct: 334 IWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQL 382
Score = 70.9 bits (166), Expect = 7e-12
Identities = 51/223 (22%), Positives = 93/223 (41%)
Query: 145 LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIA 204
L RL+ + F+ LK L L + ++ +P +A L L+ L + N I+
Sbjct: 40 LEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLIS 99
Query: 205 NITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDH 264
+ +F GL ++ L L+ N + +P + P L +T+ N ++ F+ L
Sbjct: 100 LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTS 159
Query: 265 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRV 324
+ + + NN L F L L TL L+ + ++E P + L+ L N ++
Sbjct: 160 LVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKA 219
Query: 325 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 367
+P G L ++ N + + F L L T ++G
Sbjct: 220 IPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNG 262
Score = 70.1 bits (164), Expect = 1e-11
Identities = 82/305 (26%), Positives = 127/305 (41%), Gaps = 15/305 (4%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVF---KNAINPLNADAFKGLGI 120
EI A LP+L +L +S + VV N I L +F+GL
Sbjct: 124 EIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHN 183
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
+ N PV +R+L +L + + F P L+ + D I
Sbjct: 184 LETLDLNYNKLQEFPV-AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQ 242
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGA-FRGLHNVTVLSLNKNRIQALPAGLFASTP 239
+ AF L L L++ N +I +G ++ +L+L + I+ LP+G+ P
Sbjct: 243 FVGRSAFQYLPKLHTLSL--NGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLP 300
Query: 240 RLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI 299
RL L + N L S ++EI + +N + FS L +L+ L L ++I
Sbjct: 301 RLRVLELSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAI 358
Query: 300 REL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN-AVAE-LAPELFAD 356
R + PE F + L L L NQL LP + L G L L L N A+++ + + F
Sbjct: 359 RSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGG---LMHLKLKGNLALSQAFSKDSFPK 415
Query: 357 LRALE 361
LR LE
Sbjct: 416 LRILE 420
Score = 68.1 bits (159), Expect = 5e-11
Identities = 55/239 (23%), Positives = 107/239 (44%), Gaps = 2/239 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L F L + + + +P L L L + + A
Sbjct: 24 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 83
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
P L+ L L I+++P+ +F GL+ L L + +N + I A L + ++L
Sbjct: 84 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL 143
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRI +P F + L+ L + N ++L + +F GL +++ + ++ N A+
Sbjct: 144 NRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAI-R 202
Query: 285 NLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS 342
L L+ L ++I+ +PE+ F+ N L+T+ N ++ + RS + +L +L+L+
Sbjct: 203 TLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLN 261
Score = 61.7 bits (143), Expect = 4e-09
Identities = 42/156 (26%), Positives = 72/156 (46%), Gaps = 1/156 (0%)
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
++ L+ N + L GLF L L + N ++ + F GL ++ + + NN
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLG 75
Query: 277 TLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
+ LP+L++L+LD + I +PE F S LR L L N L +P L
Sbjct: 76 GIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPA 135
Query: 336 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
L ++TL+ N ++ + F +L +L + N +Q
Sbjct: 136 LQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQ 171
>AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor
protein.
Length = 915
Score = 84.2 bits (199), Expect = 7e-16
Identities = 71/268 (26%), Positives = 113/268 (42%), Gaps = 3/268 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ + AF GL ++M +P + L LP L RL+A + F
Sbjct: 48 NHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFE 107
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L++L L D +T +P A L L+ + + N I++I AF+ L ++ VL L+
Sbjct: 108 GLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHN 167
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRIQ L F L L + N + R L +QE+ NN + E F
Sbjct: 168 NRIQHLGTHSFEGLHNLETLDLNYNKLQEF-PVAIRTLGRLQELGFHNNNIKAIPEKAFM 226
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
P L+T+ + I+ + P L TLSL + + L+G T L LTL+
Sbjct: 227 GNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSL-NGAMDIQEFPDLKGTTSLEILTLTR 285
Query: 344 NAVAELAPELFADLRALETFVMDGNELQ 371
+ L + L L + N+++
Sbjct: 286 AGIRLLPSGMCQQLPRLRVLELSHNQIE 313
Score = 83.0 bits (196), Expect = 2e-15
Identities = 54/200 (27%), Positives = 94/200 (47%), Gaps = 2/200 (1%)
Query: 173 ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
+LS +T L F L LE+L + N +++I AF GL+++ +L L N++ +PA
Sbjct: 20 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 79
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTL 292
P L +L + N + +F GL ++ + + +N + +NLPAL+ +
Sbjct: 80 EALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAM 139
Query: 293 QLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAP 351
L L+ I +P+ N + L L L N+++ L G L +L L+YN + E P
Sbjct: 140 TLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEF-P 198
Query: 352 ELFADLRALETFVMDGNELQ 371
L L+ N ++
Sbjct: 199 VAIRTLGRLQELGFHNNNIK 218
Score = 76.6 bits (180), Expect = 1e-13
Identities = 73/289 (25%), Positives = 120/289 (41%), Gaps = 25/289 (8%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I+ + +F+GL + + A T +PV L +LP L L R + F
Sbjct: 96 NLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQ 155
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N L L L + +I L +F GL+ LE L++ N++ A R L + L +
Sbjct: 156 NLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPV-AIRTLGRLQELGFHN 214
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP--------- 275
N I+A+P F P L + N +++ F+ L + + ++ +
Sbjct: 215 NNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKG 274
Query: 276 ------LTLKEA--------VFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 321
LTL A + LP LR L+L + I ELP L + L N+
Sbjct: 275 TTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHRCQK-LEEIGLQHNR 333
Query: 322 LRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ + + L +L LS+NA+ + PE F+ L +L + N+L
Sbjct: 334 IWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQL 382
Score = 70.9 bits (166), Expect = 7e-12
Identities = 51/223 (22%), Positives = 93/223 (41%)
Query: 145 LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIA 204
L RL+ + F+ LK L L + ++ +P +A L L+ L + N I+
Sbjct: 40 LEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLIS 99
Query: 205 NITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDH 264
+ +F GL ++ L L+ N + +P + P L +T+ N ++ F+ L
Sbjct: 100 LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTS 159
Query: 265 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRV 324
+ + + NN L F L L TL L+ + ++E P + L+ L N ++
Sbjct: 160 LVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKA 219
Query: 325 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 367
+P G L ++ N + + F L L T ++G
Sbjct: 220 IPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNG 262
Score = 70.1 bits (164), Expect = 1e-11
Identities = 82/305 (26%), Positives = 127/305 (41%), Gaps = 15/305 (4%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVF---KNAINPLNADAFKGLGI 120
EI A LP+L +L +S + VV N I L +F+GL
Sbjct: 124 EIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHN 183
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
+ N PV +R+L +L + + F P L+ + D I
Sbjct: 184 LETLDLNYNKLQEFPV-AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQ 242
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGA-FRGLHNVTVLSLNKNRIQALPAGLFASTP 239
+ AF L L L++ N +I +G ++ +L+L + I+ LP+G+ P
Sbjct: 243 FVGRSAFQYLPKLHTLSL--NGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLP 300
Query: 240 RLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI 299
RL L + N L S ++EI + +N + FS L +L+ L L ++I
Sbjct: 301 RLRVLELSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAI 358
Query: 300 REL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN-AVAE-LAPELFAD 356
R + PE F + L L L NQL LP + L G L L L N A+++ + + F
Sbjct: 359 RSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGG---LMHLKLKGNLALSQAFSKDSFPK 415
Query: 357 LRALE 361
LR LE
Sbjct: 416 LRILE 420
Score = 68.1 bits (159), Expect = 5e-11
Identities = 55/239 (23%), Positives = 107/239 (44%), Gaps = 2/239 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L F L + + + +P L L L + + A
Sbjct: 24 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 83
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
P L+ L L I+++P+ +F GL+ L L + +N + I A L + ++L
Sbjct: 84 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL 143
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRI +P F + L+ L + N ++L + +F GL +++ + ++ N A+
Sbjct: 144 NRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAI-R 202
Query: 285 NLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS 342
L L+ L ++I+ +PE+ F+ N L+T+ N ++ + RS + +L +L+L+
Sbjct: 203 TLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLN 261
Score = 61.7 bits (143), Expect = 4e-09
Identities = 42/156 (26%), Positives = 72/156 (46%), Gaps = 1/156 (0%)
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
++ L+ N + L GLF L L + N ++ + F GL ++ + + NN
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLG 75
Query: 277 TLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
+ LP+L++L+LD + I +PE F S LR L L N L +P L
Sbjct: 76 GIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPA 135
Query: 336 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
L ++TL+ N ++ + F +L +L + N +Q
Sbjct: 136 LQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQ 171
>AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 84.2 bits (199), Expect = 7e-16
Identities = 71/268 (26%), Positives = 113/268 (42%), Gaps = 3/268 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ + AF GL ++M +P + L LP L RL+A + F
Sbjct: 48 NHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFE 107
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L++L L D +T +P A L L+ + + N I++I AF+ L ++ VL L+
Sbjct: 108 GLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHN 167
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRIQ L F L L + N + R L +QE+ NN + E F
Sbjct: 168 NRIQHLGTHSFEGLHNLETLDLNYNKLQEF-PVAIRTLGRLQELGFHNNNIKAIPEKAFM 226
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
P L+T+ + I+ + P L TLSL + + L+G T L LTL+
Sbjct: 227 GNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSL-NGAMDIQEFPDLKGTTSLEILTLTR 285
Query: 344 NAVAELAPELFADLRALETFVMDGNELQ 371
+ L + L L + N+++
Sbjct: 286 AGIRLLPSGMCQQLPRLRVLELSHNQIE 313
Score = 83.0 bits (196), Expect = 2e-15
Identities = 54/200 (27%), Positives = 94/200 (47%), Gaps = 2/200 (1%)
Query: 173 ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
+LS +T L F L LE+L + N +++I AF GL+++ +L L N++ +PA
Sbjct: 20 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 79
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTL 292
P L +L + N + +F GL ++ + + +N + +NLPAL+ +
Sbjct: 80 EALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAM 139
Query: 293 QLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAP 351
L L+ I +P+ N + L L L N+++ L G L +L L+YN + E P
Sbjct: 140 TLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEF-P 198
Query: 352 ELFADLRALETFVMDGNELQ 371
L L+ N ++
Sbjct: 199 VAIRTLGRLQELGFHNNNIK 218
Score = 76.6 bits (180), Expect = 1e-13
Identities = 73/289 (25%), Positives = 120/289 (41%), Gaps = 25/289 (8%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I+ + +F+GL + + A T +PV L +LP L L R + F
Sbjct: 96 NLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQ 155
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N L L L + +I L +F GL+ LE L++ N++ A R L + L +
Sbjct: 156 NLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPV-AIRTLGRLQELGFHN 214
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP--------- 275
N I+A+P F P L + N +++ F+ L + + ++ +
Sbjct: 215 NNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKG 274
Query: 276 ------LTLKEA--------VFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 321
LTL A + LP LR L+L + I ELP L + L N+
Sbjct: 275 TTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHRCQK-LEEIGLQHNR 333
Query: 322 LRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ + + L +L LS+NA+ + PE F+ L +L + N+L
Sbjct: 334 IWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQL 382
Score = 70.9 bits (166), Expect = 7e-12
Identities = 51/223 (22%), Positives = 93/223 (41%)
Query: 145 LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIA 204
L RL+ + F+ LK L L + ++ +P +A L L+ L + N I+
Sbjct: 40 LEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLIS 99
Query: 205 NITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDH 264
+ +F GL ++ L L+ N + +P + P L +T+ N ++ F+ L
Sbjct: 100 LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTS 159
Query: 265 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRV 324
+ + + NN L F L L TL L+ + ++E P + L+ L N ++
Sbjct: 160 LVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKA 219
Query: 325 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 367
+P G L ++ N + + F L L T ++G
Sbjct: 220 IPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNG 262
Score = 70.1 bits (164), Expect = 1e-11
Identities = 82/305 (26%), Positives = 127/305 (41%), Gaps = 15/305 (4%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVF---KNAINPLNADAFKGLGI 120
EI A LP+L +L +S + VV N I L +F+GL
Sbjct: 124 EIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHN 183
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
+ N PV +R+L +L + + F P L+ + D I
Sbjct: 184 LETLDLNYNKLQEFPV-AIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQ 242
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGA-FRGLHNVTVLSLNKNRIQALPAGLFASTP 239
+ AF L L L++ N +I +G ++ +L+L + I+ LP+G+ P
Sbjct: 243 FVGRSAFQYLPKLHTLSL--NGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLP 300
Query: 240 RLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI 299
RL L + N L S ++EI + +N + FS L +L+ L L ++I
Sbjct: 301 RLRVLELSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAI 358
Query: 300 REL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN-AVAE-LAPELFAD 356
R + PE F + L L L NQL LP + L G L L L N A+++ + + F
Sbjct: 359 RSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGG---LMHLKLKGNLALSQAFSKDSFPK 415
Query: 357 LRALE 361
LR LE
Sbjct: 416 LRILE 420
Score = 68.1 bits (159), Expect = 5e-11
Identities = 55/239 (23%), Positives = 107/239 (44%), Gaps = 2/239 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L F L + + + +P L L L + + A
Sbjct: 24 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 83
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
P L+ L L I+++P+ +F GL+ L L + +N + I A L + ++L
Sbjct: 84 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL 143
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRI +P F + L+ L + N ++L + +F GL +++ + ++ N A+
Sbjct: 144 NRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAI-R 202
Query: 285 NLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS 342
L L+ L ++I+ +PE+ F+ N L+T+ N ++ + RS + +L +L+L+
Sbjct: 203 TLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLN 261
Score = 61.7 bits (143), Expect = 4e-09
Identities = 42/156 (26%), Positives = 72/156 (46%), Gaps = 1/156 (0%)
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
++ L+ N + L GLF L L + N ++ + F GL ++ + + NN
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLG 75
Query: 277 TLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
+ LP+L++L+LD + I +PE F S LR L L N L +P L
Sbjct: 76 GIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPA 135
Query: 336 LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
L ++TL+ N ++ + F +L +L + N +Q
Sbjct: 136 LQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQ 171
>BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein.
Length = 1070
Score = 83.8 bits (198), Expect = 9e-16
Identities = 82/338 (24%), Positives = 140/338 (41%), Gaps = 10/338 (2%)
Query: 40 VGARPRDYVNIDCMGGELVCAEFPEIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVK 99
+GA V++ ++ E ++ + ++ LSL + +C H +K
Sbjct: 110 LGAASSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCF---PHGPPIK 166
Query: 100 TV-VFKNAINPLNADAFKGLGITALMM-FNAGAQTTVPVDVLRSLPKLTHFRLNAGRNIT 157
+ + N I L AF GL + L + + T +PV + LP+LT LN R
Sbjct: 167 ELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRL 225
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
+ F L+ L+L I+ L D AF GL+ + L++ N + + +G+ GL +
Sbjct: 226 IEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTAL 285
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
L L+ N I + ++ +L L + N+ LD E+ L + +++S+N
Sbjct: 286 HQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISH 345
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPEE----FISNSPLRTLSLARNQLRVLPRSVLRGQ 333
+ E F L +LR L LD + I E+ F L L L S +
Sbjct: 346 IAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLLLLEPSQSAGCSSPSQPH 405
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
TL N + +A F+ L LE + GN ++
Sbjct: 406 MSAGGRTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIR 443
Score = 54.4 bits (125), Expect = 7e-07
Identities = 44/178 (24%), Positives = 85/178 (47%), Gaps = 6/178 (3%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
LN+ N+ + I F L N+ + LN N + A+P+ L A++ +++L + N R ++
Sbjct: 73 LNLSYNKFSEIDPAGFEDLPNLQEVYLNNNELTAVPS-LGAASSHVVSLFLQHNKIRSVE 131
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL---PEEFISNSPL 312
+ ++ + +S N ++ F + P ++ L L + I L + +S S L
Sbjct: 132 GSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRS-L 190
Query: 313 RTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
TL L++N++ LP + +LT L L+ N + + F L +LE + N +
Sbjct: 191 LTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNI 247
Score = 33.9 bits (74), Expect = 1.0
Identities = 38/146 (26%), Positives = 65/146 (44%), Gaps = 6/146 (4%)
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
+ ALP L S R LNL+ N F +D F L ++QE+ ++NN LT ++ +
Sbjct: 59 LAALPGDL-PSWTRSLNLSY--NKFSEIDPAGFEDLPNLQEVYLNNN-ELTAVPSLGAAS 114
Query: 287 PALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
+ +L L + IR + + + L L L+ N + + + + L L+ N
Sbjct: 115 SHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNR 174
Query: 346 VAELAPELFADL-RALETFVMDGNEL 370
+ L F L R+L T + N +
Sbjct: 175 IGTLELGAFDGLSRSLLTLRLSKNRI 200
>AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein.
Length = 1523
Score = 83.8 bits (198), Expect = 9e-16
Identities = 51/152 (33%), Positives = 81/152 (53%), Gaps = 1/152 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L+L IT + F GL L L++ +N+++ I GAF+ L + L LNKN++Q LP
Sbjct: 66 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLP 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
LF STP+L L + N + + + FRG+ ++ +++ NN +++ F L L
Sbjct: 126 ELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEI 185
Query: 292 LQLDLSSI-RELPEEFISNSPLRTLSLARNQL 322
L L+ ++I R L F +RTL L N L
Sbjct: 186 LTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Score = 69.7 bits (163), Expect = 2e-11
Identities = 47/159 (29%), Positives = 82/159 (51%), Gaps = 3/159 (1%)
Query: 138 VLRSLPKLTHFRLNAGRN-ITLHANM-FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQ 195
V R +P+ RL+ RN IT M FA L+ L L D +++V+ AF L LE+
Sbjct: 55 VPRGIPRNAE-RLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLER 113
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L + +N++ + F+ +T L L++N+IQ +P F + NL + N ++
Sbjct: 114 LRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIE 173
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
FR L ++ + ++NN + F+++P +RTL+L
Sbjct: 174 DGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRL 212
Score = 67.3 bits (157), Expect = 9e-11
Identities = 39/145 (26%), Positives = 75/145 (51%), Gaps = 4/145 (2%)
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
++A+P G+ + RL + RN+ + F GL +++ + + +N ++ F +L
Sbjct: 52 LRAVPRGIPRNAERL---DLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDL 108
Query: 287 PALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
L L+L+ + ++ LPE ++P L L L+ NQ++ +PR RG T + +L L N
Sbjct: 109 KQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNH 168
Query: 346 VAELAPELFADLRALETFVMDGNEL 370
++ + F LR LE ++ N +
Sbjct: 169 ISCIEDGAFRALRDLEILTLNNNNI 193
Score = 66.9 bits (156), Expect = 1e-10
Identities = 41/146 (28%), Positives = 69/146 (47%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
+N I + F GL ++ + + + L +L RLN + L +F
Sbjct: 70 RNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLF 129
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
+TP L L+LS+ +I +P AF G+ ++ L + N I+ I GAFR L ++ +L+LN
Sbjct: 130 QSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLN 189
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRN 249
N I + F P++ L + N
Sbjct: 190 NNNISRILVTSFNHMPKIRTLRLHSN 215
Score = 63.7 bits (148), Expect = 1e-09
Identities = 38/132 (28%), Positives = 69/132 (52%), Gaps = 1/132 (0%)
Query: 164 ANTPP-LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
AN P + + L I +P AF L+++++ +N+I++I AF+GL ++T L L
Sbjct: 303 ANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVL 362
Query: 223 NKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAV 282
N+I + GLF L L + N L TF+ L ++ + + +N T+ + +
Sbjct: 363 YGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGL 422
Query: 283 FSNLPALRTLQL 294
F+ L +++TL L
Sbjct: 423 FAPLQSIQTLHL 434
Score = 62.5 bits (145), Expect = 3e-09
Identities = 39/139 (28%), Positives = 66/139 (47%), Gaps = 1/139 (0%)
Query: 136 VDVLRSLPK-LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLE 194
+++ +LP+ + RL + A F LK +++S +I+ + DAF GL L
Sbjct: 299 MEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLT 358
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
L ++ N+I I G F GL ++ +L LN N+I L F L L++ N + +
Sbjct: 359 SLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTI 418
Query: 255 DSETFRGLDHIQEIKISNN 273
F L IQ + ++ N
Sbjct: 419 SKGLFAPLQSIQTLHLAQN 437
Score = 56.0 bits (129), Expect = 2e-07
Identities = 34/124 (27%), Positives = 62/124 (50%), Gaps = 1/124 (0%)
Query: 172 LELSDAKITVLPDDA-FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
L L+D +++VL F L L ++N+ N+I + GAF G +V L L N+++ +
Sbjct: 537 LRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETV 596
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
+F L L + N + ++TF GL ++ + + +N T+ F+ L +L
Sbjct: 597 HGRVFRGLSGLKTLMLRSNLISCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLS 656
Query: 291 TLQL 294
T+ L
Sbjct: 657 TINL 660
Score = 54.8 bits (126), Expect = 5e-07
Identities = 36/132 (27%), Positives = 62/132 (46%)
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
L L L + + F + L+ L L+ K+ VLP+ F L +L++ EN
Sbjct: 84 LKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSEN 143
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG 261
+I I AFRG+ +V L L+ N I + G F + L LT+ N+ + +F
Sbjct: 144 QIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNH 203
Query: 262 LDHIQEIKISNN 273
+ I+ +++ +N
Sbjct: 204 MPKIRTLRLHSN 215
Score = 52.8 bits (121), Expect = 2e-06
Identities = 58/274 (21%), Positives = 109/274 (39%), Gaps = 9/274 (3%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ + AF+ L + N +P + +S PKLT L+ + + F
Sbjct: 95 NQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFR 154
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
+K L+L + I+ + D AF L LE L + N I+ I +F + + L L+
Sbjct: 155 GITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHS 214
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N + L + L + + RG + K P E
Sbjct: 215 NHLYC-DCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEPPSC 273
Query: 285 N-----LPALRTLQLDLSSIR-ELPEEFISNSPLRTLSLARNQ--LRVLPRSVLRGQTQL 336
N P+ T ++ R + E +N P + + Q ++ +P +L
Sbjct: 274 NANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKL 333
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ +S N ++++AP+ F L++L + V+ GN++
Sbjct: 334 KRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKI 367
Score = 49.6 bits (113), Expect = 2e-05
Identities = 31/129 (24%), Positives = 61/129 (47%), Gaps = 1/129 (0%)
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
+ + L +N I+A+PAG F +L + + +N + + F+GL + + + N
Sbjct: 309 IVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKIT 368
Query: 277 TLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
+ + +F L +L+ L L+ + I L F L LSL N+L+ + + +
Sbjct: 369 EIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQS 428
Query: 336 LTSLTLSYN 344
+ +L L+ N
Sbjct: 429 IQTLHLAQN 437
Score = 48.4 bits (110), Expect = 4e-05
Identities = 32/118 (27%), Positives = 52/118 (44%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
+P KL ++ + + + F L L L KIT + F GL L
Sbjct: 322 IPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSL 381
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
+ L + N+I + F+ L N+ +LSL N++Q + GLFA + L + +N F
Sbjct: 382 QLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPF 439
Score = 48.0 bits (109), Expect = 6e-05
Identities = 29/114 (25%), Positives = 53/114 (46%)
Query: 138 VLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
+ + LP L L+ + + F ++ L L+ ++ + F GL+ L+ L
Sbjct: 552 IFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLM 611
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
+ N I+ ++ F GL +V +LSL NRI + G F + L + ++ N F
Sbjct: 612 LRSNLISCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPF 665
Score = 45.6 bits (103), Expect = 3e-04
Identities = 25/89 (28%), Positives = 50/89 (56%), Gaps = 2/89 (2%)
Query: 284 SNLP-ALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTL 341
+NLP + ++L+ +SI+ +P F L+ + +++NQ+ + +G LTSL L
Sbjct: 303 ANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVL 362
Query: 342 SYNAVAELAPELFADLRALETFVMDGNEL 370
N + E+A LF L +L+ +++ N++
Sbjct: 363 YGNKITEIAKGLFDGLVSLQLLLLNANKI 391
Score = 45.6 bits (103), Expect = 3e-04
Identities = 28/110 (25%), Positives = 58/110 (52%), Gaps = 2/110 (1%)
Query: 263 DHIQEIKISNNVPLTLKEA-VFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARN 320
+++ ++++++N L+ +F LP LR + L + I+E+ E F + ++ L L N
Sbjct: 532 EYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGN 591
Query: 321 QLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
QL + V RG + L +L L N ++ ++ + FA L ++ + N +
Sbjct: 592 QLETVHGRVFRGLSGLKTLMLRSNLISCVSNDTFAGLSSVRLLSLYDNRI 641
Score = 44.4 bits (100), Expect = 7e-04
Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 2/111 (1%)
Query: 140 RSLPK-LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
R +PK +T L G ++T + L ++LS+ I++L + F ++ L L +
Sbjct: 748 RGMPKDVTELYLE-GNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLIL 806
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
N + I AF GL ++ VL+L+ N I ++P G F L +L + N
Sbjct: 807 SYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTN 857
Score = 43.2 bits (97), Expect = 0.002
Identities = 35/128 (27%), Positives = 54/128 (42%), Gaps = 5/128 (3%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
TV+ + ++ALP G+ P+ + + + L H+ I +SNN
Sbjct: 734 TVVRCSNKGLRALPRGM----PKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISM 789
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
L FSN+ L TL L + +R +P F LR L+L N + +P T L
Sbjct: 790 LTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSL 849
Query: 337 TSLTLSYN 344
+ L L N
Sbjct: 850 SHLALGTN 857
Score = 41.9 bits (94), Expect = 0.004
Identities = 65/287 (22%), Positives = 125/287 (43%), Gaps = 29/287 (10%)
Query: 102 VFKNAINPLNADAFKGL-GITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHA 160
+ KN I+ + DAF+GL +T+L+++ T + + L L LNA + L
Sbjct: 338 ISKNQISDIAPDAFQGLKSLTSLVLY-GNKITEIAKGLFDGLVSLQLLLLNANKINCLRV 396
Query: 161 NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVL 220
N F + L L L D K+ + F L ++ L++ +N + + L +
Sbjct: 397 NTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPF--VCDCHLKWLADY--- 451
Query: 221 SLNKNRIQALPAGLFASTPRLL---NLTMMRN-SFRYLDSETFRG-------LDHI--QE 267
L N I+ +G S+PR L ++ +++ FR SE +R +D + ++
Sbjct: 452 -LQDNPIET--SGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEK 508
Query: 268 IKISNNVPLTLKEAVF---SNLPALRT-LQLDLS--SIRELPEEFISNSPLRTLSLARNQ 321
+ + + + S+LP T L+L+ + S+ E F LR ++L+ N+
Sbjct: 509 CRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNK 568
Query: 322 LRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
++ + G + L L+ N + + +F L L+T ++ N
Sbjct: 569 IKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSN 615
Score = 41.1 bits (92), Expect = 0.007
Identities = 37/94 (39%), Positives = 45/94 (47%), Gaps = 4/94 (4%)
Query: 281 AVFSNLPALRTLQL-DLS--SIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQL 336
AV L ALR L L DLS SI L SN S L TL L+ N+LR +P G L
Sbjct: 766 AVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSL 825
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
LTL N ++ + F DL +L + N L
Sbjct: 826 RVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 859
Score = 39.9 bits (89), Expect = 0.015
Identities = 29/91 (31%), Positives = 47/91 (51%), Gaps = 3/91 (3%)
Query: 138 VLRSLPKLTHFRLN--AGRNITLHANM-FANTPPLKYLELSDAKITVLPDDAFLGLNVLE 194
V R L L H L + +I++ N F+N L L LS ++ +P AF GL L
Sbjct: 767 VPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLR 826
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
L + N+I+++ G+F L +++ L+L N
Sbjct: 827 VLTLHGNDISSVPEGSFNDLTSLSHLALGTN 857
Score = 38.7 bits (86), Expect = 0.035
Identities = 20/79 (25%), Positives = 38/79 (48%)
Query: 292 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAP 351
L L+ + + +P E + L + L+ N + +L + L++L LSYN + +
Sbjct: 757 LYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPV 816
Query: 352 ELFADLRALETFVMDGNEL 370
F LR+L + GN++
Sbjct: 817 HAFNGLRSLRVLTLHGNDI 835
Score = 38.3 bits (85), Expect = 0.047
Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 1/108 (0%)
Query: 265 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLR 323
I EI++ N + F+ L+ + + + I ++ P+ F L +L L N++
Sbjct: 309 IVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKIT 368
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
+ + + G L L L+ N + L F DL+ L + N+LQ
Sbjct: 369 EIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQ 416
Score = 35.5 bits (78), Expect = 0.33
Identities = 23/102 (22%), Positives = 45/102 (44%), Gaps = 1/102 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L +T +P + L L +++ N I+ +T F + +++ L L+ NR++ +P
Sbjct: 757 LYLEGNHLTAVPRE-LSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIP 815
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
F L LT+ N + +F L + + + N
Sbjct: 816 VHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTN 857
Score = 33.1 bits (72), Expect = 1.8
Identities = 30/136 (22%), Positives = 49/136 (36%), Gaps = 6/136 (4%)
Query: 15 CPEQCWCTDGEELNYQCSRPSTNLIVGARPRDYVNIDCMGGELVCAEFPEIDTPATTQLP 74
CPEQC C E +CS + P+D + G L P + A L
Sbjct: 725 CPEQCTCM---ETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAV--PR-ELSALRHLT 778
Query: 75 SLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTV 134
+ L S+ L+ + ++ N + + AF GL ++ + ++V
Sbjct: 779 LIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSV 838
Query: 135 PVDVLRSLPKLTHFRL 150
P L L+H L
Sbjct: 839 PEGSFNDLTSLSHLAL 854
Score = 31.1 bits (67), Expect = 7.1
Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
Query: 299 IRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 358
+R +P N+ L L RN + + + G L L L N V+ + F DL+
Sbjct: 52 LRAVPRGIPRNA--ERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLK 109
Query: 359 ALETFVMDGNELQV 372
LE ++ N+LQV
Sbjct: 110 QLERLRLNKNKLQV 123
>AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein.
Length = 1523
Score = 83.8 bits (198), Expect = 9e-16
Identities = 51/152 (33%), Positives = 81/152 (53%), Gaps = 1/152 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L+L IT + F GL L L++ +N+++ I GAF+ L + L LNKN++Q LP
Sbjct: 66 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLP 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
LF STP+L L + N + + + FRG+ ++ +++ NN +++ F L L
Sbjct: 126 ELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEI 185
Query: 292 LQLDLSSI-RELPEEFISNSPLRTLSLARNQL 322
L L+ ++I R L F +RTL L N L
Sbjct: 186 LTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Score = 69.7 bits (163), Expect = 2e-11
Identities = 47/159 (29%), Positives = 82/159 (51%), Gaps = 3/159 (1%)
Query: 138 VLRSLPKLTHFRLNAGRN-ITLHANM-FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQ 195
V R +P+ RL+ RN IT M FA L+ L L D +++V+ AF L LE+
Sbjct: 55 VPRGIPRNAE-RLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLER 113
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L + +N++ + F+ +T L L++N+IQ +P F + NL + N ++
Sbjct: 114 LRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIE 173
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
FR L ++ + ++NN + F+++P +RTL+L
Sbjct: 174 DGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRL 212
Score = 67.3 bits (157), Expect = 9e-11
Identities = 39/145 (26%), Positives = 75/145 (51%), Gaps = 4/145 (2%)
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
++A+P G+ + RL + RN+ + F GL +++ + + +N ++ F +L
Sbjct: 52 LRAVPRGIPRNAERL---DLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDL 108
Query: 287 PALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
L L+L+ + ++ LPE ++P L L L+ NQ++ +PR RG T + +L L N
Sbjct: 109 KQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNH 168
Query: 346 VAELAPELFADLRALETFVMDGNEL 370
++ + F LR LE ++ N +
Sbjct: 169 ISCIEDGAFRALRDLEILTLNNNNI 193
Score = 66.9 bits (156), Expect = 1e-10
Identities = 41/146 (28%), Positives = 69/146 (47%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
+N I + F GL ++ + + + L +L RLN + L +F
Sbjct: 70 RNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLF 129
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
+TP L L+LS+ +I +P AF G+ ++ L + N I+ I GAFR L ++ +L+LN
Sbjct: 130 QSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLN 189
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRN 249
N I + F P++ L + N
Sbjct: 190 NNNISRILVTSFNHMPKIRTLRLHSN 215
Score = 63.7 bits (148), Expect = 1e-09
Identities = 38/132 (28%), Positives = 69/132 (52%), Gaps = 1/132 (0%)
Query: 164 ANTPP-LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
AN P + + L I +P AF L+++++ +N+I++I AF+GL ++T L L
Sbjct: 303 ANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVL 362
Query: 223 NKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAV 282
N+I + GLF L L + N L TF+ L ++ + + +N T+ + +
Sbjct: 363 YGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGL 422
Query: 283 FSNLPALRTLQL 294
F+ L +++TL L
Sbjct: 423 FAPLQSIQTLHL 434
Score = 62.5 bits (145), Expect = 3e-09
Identities = 39/139 (28%), Positives = 66/139 (47%), Gaps = 1/139 (0%)
Query: 136 VDVLRSLPK-LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLE 194
+++ +LP+ + RL + A F LK +++S +I+ + DAF GL L
Sbjct: 299 MEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLT 358
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
L ++ N+I I G F GL ++ +L LN N+I L F L L++ N + +
Sbjct: 359 SLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTI 418
Query: 255 DSETFRGLDHIQEIKISNN 273
F L IQ + ++ N
Sbjct: 419 SKGLFAPLQSIQTLHLAQN 437
Score = 55.6 bits (128), Expect = 3e-07
Identities = 34/124 (27%), Positives = 62/124 (50%), Gaps = 1/124 (0%)
Query: 172 LELSDAKITVLPDDA-FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
L L+D +++VL F L L ++N+ N+I + GAF G +V L L N+++ +
Sbjct: 537 LRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETV 596
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
+F L L + N + ++TF GL ++ + + +N T+ F+ L +L
Sbjct: 597 HGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLS 656
Query: 291 TLQL 294
T+ L
Sbjct: 657 TINL 660
Score = 54.8 bits (126), Expect = 5e-07
Identities = 36/132 (27%), Positives = 62/132 (46%)
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
L L L + + F + L+ L L+ K+ VLP+ F L +L++ EN
Sbjct: 84 LKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSEN 143
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG 261
+I I AFRG+ +V L L+ N I + G F + L LT+ N+ + +F
Sbjct: 144 QIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNH 203
Query: 262 LDHIQEIKISNN 273
+ I+ +++ +N
Sbjct: 204 MPKIRTLRLHSN 215
Score = 52.8 bits (121), Expect = 2e-06
Identities = 58/274 (21%), Positives = 109/274 (39%), Gaps = 9/274 (3%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ + AF+ L + N +P + +S PKLT L+ + + F
Sbjct: 95 NQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFR 154
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
+K L+L + I+ + D AF L LE L + N I+ I +F + + L L+
Sbjct: 155 GITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHS 214
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N + L + L + + RG + K P E
Sbjct: 215 NHLYC-DCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEPPSC 273
Query: 285 N-----LPALRTLQLDLSSIR-ELPEEFISNSPLRTLSLARNQ--LRVLPRSVLRGQTQL 336
N P+ T ++ R + E +N P + + Q ++ +P +L
Sbjct: 274 NANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKL 333
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ +S N ++++AP+ F L++L + V+ GN++
Sbjct: 334 KRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKI 367
Score = 49.6 bits (113), Expect = 2e-05
Identities = 31/129 (24%), Positives = 61/129 (47%), Gaps = 1/129 (0%)
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
+ + L +N I+A+PAG F +L + + +N + + F+GL + + + N
Sbjct: 309 IVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKIT 368
Query: 277 TLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
+ + +F L +L+ L L+ + I L F L LSL N+L+ + + +
Sbjct: 369 EIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQS 428
Query: 336 LTSLTLSYN 344
+ +L L+ N
Sbjct: 429 IQTLHLAQN 437
Score = 48.4 bits (110), Expect = 4e-05
Identities = 32/118 (27%), Positives = 52/118 (44%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
+P KL ++ + + + F L L L KIT + F GL L
Sbjct: 322 IPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSL 381
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
+ L + N+I + F+ L N+ +LSL N++Q + GLFA + L + +N F
Sbjct: 382 QLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPF 439
Score = 47.6 bits (108), Expect = 8e-05
Identities = 29/114 (25%), Positives = 52/114 (45%)
Query: 138 VLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
+ + LP L L+ + + F ++ L L+ ++ + F GL+ L+ L
Sbjct: 552 IFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLM 611
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
+ N I ++ F GL +V +LSL NRI + G F + L + ++ N F
Sbjct: 612 LRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPF 665
Score = 45.6 bits (103), Expect = 3e-04
Identities = 25/89 (28%), Positives = 50/89 (56%), Gaps = 2/89 (2%)
Query: 284 SNLP-ALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTL 341
+NLP + ++L+ +SI+ +P F L+ + +++NQ+ + +G LTSL L
Sbjct: 303 ANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVL 362
Query: 342 SYNAVAELAPELFADLRALETFVMDGNEL 370
N + E+A LF L +L+ +++ N++
Sbjct: 363 YGNKITEIAKGLFDGLVSLQLLLLNANKI 391
Score = 45.2 bits (102), Expect = 4e-04
Identities = 28/110 (25%), Positives = 57/110 (51%), Gaps = 2/110 (1%)
Query: 263 DHIQEIKISNNVPLTLKEA-VFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARN 320
+++ ++++++N L+ +F LP LR + L + I+E+ E F + ++ L L N
Sbjct: 532 EYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGN 591
Query: 321 QLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
QL + V RG + L +L L N + ++ + FA L ++ + N +
Sbjct: 592 QLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRI 641
Score = 44.4 bits (100), Expect = 7e-04
Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 2/111 (1%)
Query: 140 RSLPK-LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
R +PK +T L G ++T + L ++LS+ I++L + F ++ L L +
Sbjct: 748 RGMPKDVTELYLE-GNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLIL 806
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
N + I AF GL ++ VL+L+ N I ++P G F L +L + N
Sbjct: 807 SYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTN 857
Score = 43.2 bits (97), Expect = 0.002
Identities = 35/128 (27%), Positives = 54/128 (42%), Gaps = 5/128 (3%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
TV+ + ++ALP G+ P+ + + + L H+ I +SNN
Sbjct: 734 TVVRCSNKGLRALPRGM----PKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISM 789
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
L FSN+ L TL L + +R +P F LR L+L N + +P T L
Sbjct: 790 LTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSL 849
Query: 337 TSLTLSYN 344
+ L L N
Sbjct: 850 SHLALGTN 857
Score = 41.9 bits (94), Expect = 0.004
Identities = 65/287 (22%), Positives = 125/287 (43%), Gaps = 29/287 (10%)
Query: 102 VFKNAINPLNADAFKGL-GITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHA 160
+ KN I+ + DAF+GL +T+L+++ T + + L L LNA + L
Sbjct: 338 ISKNQISDIAPDAFQGLKSLTSLVLY-GNKITEIAKGLFDGLVSLQLLLLNANKINCLRV 396
Query: 161 NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVL 220
N F + L L L D K+ + F L ++ L++ +N + + L +
Sbjct: 397 NTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPF--VCDCHLKWLADY--- 451
Query: 221 SLNKNRIQALPAGLFASTPRLL---NLTMMRN-SFRYLDSETFRG-------LDHI--QE 267
L N I+ +G S+PR L ++ +++ FR SE +R +D + ++
Sbjct: 452 -LQDNPIET--SGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEK 508
Query: 268 IKISNNVPLTLKEAVF---SNLPALRT-LQLDLS--SIRELPEEFISNSPLRTLSLARNQ 321
+ + + + S+LP T L+L+ + S+ E F LR ++L+ N+
Sbjct: 509 CRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNK 568
Query: 322 LRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
++ + G + L L+ N + + +F L L+T ++ N
Sbjct: 569 IKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSN 615
Score = 41.1 bits (92), Expect = 0.007
Identities = 37/94 (39%), Positives = 45/94 (47%), Gaps = 4/94 (4%)
Query: 281 AVFSNLPALRTLQL-DLS--SIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQL 336
AV L ALR L L DLS SI L SN S L TL L+ N+LR +P G L
Sbjct: 766 AVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSL 825
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
LTL N ++ + F DL +L + N L
Sbjct: 826 RVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 859
Score = 39.9 bits (89), Expect = 0.015
Identities = 29/91 (31%), Positives = 47/91 (51%), Gaps = 3/91 (3%)
Query: 138 VLRSLPKLTHFRLN--AGRNITLHANM-FANTPPLKYLELSDAKITVLPDDAFLGLNVLE 194
V R L L H L + +I++ N F+N L L LS ++ +P AF GL L
Sbjct: 767 VPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLR 826
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
L + N+I+++ G+F L +++ L+L N
Sbjct: 827 VLTLHGNDISSVPEGSFNDLTSLSHLALGTN 857
Score = 38.7 bits (86), Expect = 0.035
Identities = 20/79 (25%), Positives = 38/79 (48%)
Query: 292 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAP 351
L L+ + + +P E + L + L+ N + +L + L++L LSYN + +
Sbjct: 757 LYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPV 816
Query: 352 ELFADLRALETFVMDGNEL 370
F LR+L + GN++
Sbjct: 817 HAFNGLRSLRVLTLHGNDI 835
Score = 38.3 bits (85), Expect = 0.047
Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 1/108 (0%)
Query: 265 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLR 323
I EI++ N + F+ L+ + + + I ++ P+ F L +L L N++
Sbjct: 309 IVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKIT 368
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
+ + + G L L L+ N + L F DL+ L + N+LQ
Sbjct: 369 EIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQ 416
Score = 35.5 bits (78), Expect = 0.33
Identities = 23/102 (22%), Positives = 45/102 (44%), Gaps = 1/102 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L +T +P + L L +++ N I+ +T F + +++ L L+ NR++ +P
Sbjct: 757 LYLEGNHLTAVPRE-LSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIP 815
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
F L LT+ N + +F L + + + N
Sbjct: 816 VHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTN 857
Score = 33.1 bits (72), Expect = 1.8
Identities = 30/136 (22%), Positives = 49/136 (36%), Gaps = 6/136 (4%)
Query: 15 CPEQCWCTDGEELNYQCSRPSTNLIVGARPRDYVNIDCMGGELVCAEFPEIDTPATTQLP 74
CPEQC C E +CS + P+D + G L P + A L
Sbjct: 725 CPEQCTCM---ETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAV--PR-ELSALRHLT 778
Query: 75 SLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTV 134
+ L S+ L+ + ++ N + + AF GL ++ + ++V
Sbjct: 779 LIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSV 838
Query: 135 PVDVLRSLPKLTHFRL 150
P L L+H L
Sbjct: 839 PEGSFNDLTSLSHLAL 854
Score = 31.1 bits (67), Expect = 7.1
Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
Query: 299 IRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 358
+R +P N+ L L RN + + + G L L L N V+ + F DL+
Sbjct: 52 LRAVPRGIPRNA--ERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLK 109
Query: 359 ALETFVMDGNELQV 372
LE ++ N+LQV
Sbjct: 110 QLERLRLNKNKLQV 123
>AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein.
Length = 1559
Score = 83.8 bits (198), Expect = 9e-16
Identities = 51/152 (33%), Positives = 81/152 (53%), Gaps = 1/152 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L+L IT + F GL L L++ +N+++ I GAF+ L + L LNKN++Q LP
Sbjct: 102 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLP 161
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
LF STP+L L + N + + + FRG+ ++ +++ NN +++ F L L
Sbjct: 162 ELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEI 221
Query: 292 LQLDLSSI-RELPEEFISNSPLRTLSLARNQL 322
L L+ ++I R L F +RTL L N L
Sbjct: 222 LTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 253
Score = 69.7 bits (163), Expect = 2e-11
Identities = 47/159 (29%), Positives = 82/159 (51%), Gaps = 3/159 (1%)
Query: 138 VLRSLPKLTHFRLNAGRN-ITLHANM-FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQ 195
V R +P+ RL+ RN IT M FA L+ L L D +++V+ AF L LE+
Sbjct: 91 VPRGIPRNAE-RLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLER 149
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L + +N++ + F+ +T L L++N+IQ +P F + NL + N ++
Sbjct: 150 LRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIE 209
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
FR L ++ + ++NN + F+++P +RTL+L
Sbjct: 210 DGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRL 248
Score = 67.3 bits (157), Expect = 9e-11
Identities = 39/145 (26%), Positives = 75/145 (51%), Gaps = 4/145 (2%)
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
++A+P G+ + RL + RN+ + F GL +++ + + +N ++ F +L
Sbjct: 88 LRAVPRGIPRNAERL---DLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDL 144
Query: 287 PALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
L L+L+ + ++ LPE ++P L L L+ NQ++ +PR RG T + +L L N
Sbjct: 145 KQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNH 204
Query: 346 VAELAPELFADLRALETFVMDGNEL 370
++ + F LR LE ++ N +
Sbjct: 205 ISCIEDGAFRALRDLEILTLNNNNI 229
Score = 66.9 bits (156), Expect = 1e-10
Identities = 41/146 (28%), Positives = 69/146 (47%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
+N I + F GL ++ + + + L +L RLN + L +F
Sbjct: 106 RNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLF 165
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
+TP L L+LS+ +I +P AF G+ ++ L + N I+ I GAFR L ++ +L+LN
Sbjct: 166 QSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLN 225
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRN 249
N I + F P++ L + N
Sbjct: 226 NNNISRILVTSFNHMPKIRTLRLHSN 251
Score = 63.7 bits (148), Expect = 1e-09
Identities = 38/132 (28%), Positives = 69/132 (52%), Gaps = 1/132 (0%)
Query: 164 ANTPP-LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
AN P + + L I +P AF L+++++ +N+I++I AF+GL ++T L L
Sbjct: 339 ANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVL 398
Query: 223 NKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAV 282
N+I + GLF L L + N L TF+ L ++ + + +N T+ + +
Sbjct: 399 YGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGL 458
Query: 283 FSNLPALRTLQL 294
F+ L +++TL L
Sbjct: 459 FAPLQSIQTLHL 470
Score = 62.5 bits (145), Expect = 3e-09
Identities = 39/139 (28%), Positives = 66/139 (47%), Gaps = 1/139 (0%)
Query: 136 VDVLRSLPK-LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLE 194
+++ +LP+ + RL + A F LK +++S +I+ + DAF GL L
Sbjct: 335 MEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLT 394
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
L ++ N+I I G F GL ++ +L LN N+I L F L L++ N + +
Sbjct: 395 SLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTI 454
Query: 255 DSETFRGLDHIQEIKISNN 273
F L IQ + ++ N
Sbjct: 455 SKGLFAPLQSIQTLHLAQN 473
Score = 55.6 bits (128), Expect = 3e-07
Identities = 34/124 (27%), Positives = 62/124 (50%), Gaps = 1/124 (0%)
Query: 172 LELSDAKITVLPDDA-FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
L L+D +++VL F L L ++N+ N+I + GAF G +V L L N+++ +
Sbjct: 573 LRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETV 632
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
+F L L + N + ++TF GL ++ + + +N T+ F+ L +L
Sbjct: 633 HGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLS 692
Query: 291 TLQL 294
T+ L
Sbjct: 693 TINL 696
Score = 54.8 bits (126), Expect = 5e-07
Identities = 36/132 (27%), Positives = 62/132 (46%)
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
L L L + + F + L+ L L+ K+ VLP+ F L +L++ EN
Sbjct: 120 LKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSEN 179
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG 261
+I I AFRG+ +V L L+ N I + G F + L LT+ N+ + +F
Sbjct: 180 QIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNH 239
Query: 262 LDHIQEIKISNN 273
+ I+ +++ +N
Sbjct: 240 MPKIRTLRLHSN 251
Score = 52.8 bits (121), Expect = 2e-06
Identities = 58/274 (21%), Positives = 109/274 (39%), Gaps = 9/274 (3%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ + AF+ L + N +P + +S PKLT L+ + + F
Sbjct: 131 NQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFR 190
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
+K L+L + I+ + D AF L LE L + N I+ I +F + + L L+
Sbjct: 191 GITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHS 250
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N + L + L + + RG + K P E
Sbjct: 251 NHLYC-DCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEPPSC 309
Query: 285 N-----LPALRTLQLDLSSIR-ELPEEFISNSPLRTLSLARNQ--LRVLPRSVLRGQTQL 336
N P+ T ++ R + E +N P + + Q ++ +P +L
Sbjct: 310 NANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKL 369
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ +S N ++++AP+ F L++L + V+ GN++
Sbjct: 370 KRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKI 403
Score = 49.6 bits (113), Expect = 2e-05
Identities = 31/129 (24%), Positives = 61/129 (47%), Gaps = 1/129 (0%)
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
+ + L +N I+A+PAG F +L + + +N + + F+GL + + + N
Sbjct: 345 IVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKIT 404
Query: 277 TLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
+ + +F L +L+ L L+ + I L F L LSL N+L+ + + +
Sbjct: 405 EIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQS 464
Query: 336 LTSLTLSYN 344
+ +L L+ N
Sbjct: 465 IQTLHLAQN 473
Score = 48.4 bits (110), Expect = 4e-05
Identities = 32/118 (27%), Positives = 52/118 (44%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
+P KL ++ + + + F L L L KIT + F GL L
Sbjct: 358 IPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSL 417
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
+ L + N+I + F+ L N+ +LSL N++Q + GLFA + L + +N F
Sbjct: 418 QLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPF 475
Score = 47.6 bits (108), Expect = 8e-05
Identities = 29/114 (25%), Positives = 52/114 (45%)
Query: 138 VLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
+ + LP L L+ + + F ++ L L+ ++ + F GL+ L+ L
Sbjct: 588 IFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLM 647
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
+ N I ++ F GL +V +LSL NRI + G F + L + ++ N F
Sbjct: 648 LRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPF 701
Score = 45.6 bits (103), Expect = 3e-04
Identities = 25/89 (28%), Positives = 50/89 (56%), Gaps = 2/89 (2%)
Query: 284 SNLP-ALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTL 341
+NLP + ++L+ +SI+ +P F L+ + +++NQ+ + +G LTSL L
Sbjct: 339 ANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVL 398
Query: 342 SYNAVAELAPELFADLRALETFVMDGNEL 370
N + E+A LF L +L+ +++ N++
Sbjct: 399 YGNKITEIAKGLFDGLVSLQLLLLNANKI 427
Score = 45.2 bits (102), Expect = 4e-04
Identities = 28/110 (25%), Positives = 57/110 (51%), Gaps = 2/110 (1%)
Query: 263 DHIQEIKISNNVPLTLKEA-VFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARN 320
+++ ++++++N L+ +F LP LR + L + I+E+ E F + ++ L L N
Sbjct: 568 EYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGN 627
Query: 321 QLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
QL + V RG + L +L L N + ++ + FA L ++ + N +
Sbjct: 628 QLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRI 677
Score = 44.4 bits (100), Expect = 7e-04
Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 2/111 (1%)
Query: 140 RSLPK-LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
R +PK +T L G ++T + L ++LS+ I++L + F ++ L L +
Sbjct: 784 RGMPKDVTELYLE-GNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLIL 842
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
N + I AF GL ++ VL+L+ N I ++P G F L +L + N
Sbjct: 843 SYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTN 893
Score = 43.2 bits (97), Expect = 0.002
Identities = 35/128 (27%), Positives = 54/128 (42%), Gaps = 5/128 (3%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
TV+ + ++ALP G+ P+ + + + L H+ I +SNN
Sbjct: 770 TVVRCSNKGLRALPRGM----PKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISM 825
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
L FSN+ L TL L + +R +P F LR L+L N + +P T L
Sbjct: 826 LTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSL 885
Query: 337 TSLTLSYN 344
+ L L N
Sbjct: 886 SHLALGTN 893
Score = 41.9 bits (94), Expect = 0.004
Identities = 65/287 (22%), Positives = 125/287 (43%), Gaps = 29/287 (10%)
Query: 102 VFKNAINPLNADAFKGL-GITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHA 160
+ KN I+ + DAF+GL +T+L+++ T + + L L LNA + L
Sbjct: 374 ISKNQISDIAPDAFQGLKSLTSLVLY-GNKITEIAKGLFDGLVSLQLLLLNANKINCLRV 432
Query: 161 NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVL 220
N F + L L L D K+ + F L ++ L++ +N + + L +
Sbjct: 433 NTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPF--VCDCHLKWLADY--- 487
Query: 221 SLNKNRIQALPAGLFASTPRLL---NLTMMRN-SFRYLDSETFRG-------LDHI--QE 267
L N I+ +G S+PR L ++ +++ FR SE +R +D + ++
Sbjct: 488 -LQDNPIET--SGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEK 544
Query: 268 IKISNNVPLTLKEAVF---SNLPALRT-LQLDLS--SIRELPEEFISNSPLRTLSLARNQ 321
+ + + + S+LP T L+L+ + S+ E F LR ++L+ N+
Sbjct: 545 CRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNK 604
Query: 322 LRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
++ + G + L L+ N + + +F L L+T ++ N
Sbjct: 605 IKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSN 651
Score = 41.1 bits (92), Expect = 0.007
Identities = 37/94 (39%), Positives = 45/94 (47%), Gaps = 4/94 (4%)
Query: 281 AVFSNLPALRTLQL-DLS--SIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQL 336
AV L ALR L L DLS SI L SN S L TL L+ N+LR +P G L
Sbjct: 802 AVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSL 861
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
LTL N ++ + F DL +L + N L
Sbjct: 862 RVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 895
Score = 39.9 bits (89), Expect = 0.015
Identities = 29/91 (31%), Positives = 47/91 (51%), Gaps = 3/91 (3%)
Query: 138 VLRSLPKLTHFRLN--AGRNITLHANM-FANTPPLKYLELSDAKITVLPDDAFLGLNVLE 194
V R L L H L + +I++ N F+N L L LS ++ +P AF GL L
Sbjct: 803 VPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLR 862
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
L + N+I+++ G+F L +++ L+L N
Sbjct: 863 VLTLHGNDISSVPEGSFNDLTSLSHLALGTN 893
Score = 38.7 bits (86), Expect = 0.035
Identities = 20/79 (25%), Positives = 38/79 (48%)
Query: 292 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAP 351
L L+ + + +P E + L + L+ N + +L + L++L LSYN + +
Sbjct: 793 LYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPV 852
Query: 352 ELFADLRALETFVMDGNEL 370
F LR+L + GN++
Sbjct: 853 HAFNGLRSLRVLTLHGNDI 871
Score = 38.3 bits (85), Expect = 0.047
Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 1/108 (0%)
Query: 265 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLR 323
I EI++ N + F+ L+ + + + I ++ P+ F L +L L N++
Sbjct: 345 IVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKIT 404
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
+ + + G L L L+ N + L F DL+ L + N+LQ
Sbjct: 405 EIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQ 452
Score = 35.5 bits (78), Expect = 0.33
Identities = 23/102 (22%), Positives = 45/102 (44%), Gaps = 1/102 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L +T +P + L L +++ N I+ +T F + +++ L L+ NR++ +P
Sbjct: 793 LYLEGNHLTAVPRE-LSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIP 851
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
F L LT+ N + +F L + + + N
Sbjct: 852 VHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTN 893
Score = 33.1 bits (72), Expect = 1.8
Identities = 30/136 (22%), Positives = 49/136 (36%), Gaps = 6/136 (4%)
Query: 15 CPEQCWCTDGEELNYQCSRPSTNLIVGARPRDYVNIDCMGGELVCAEFPEIDTPATTQLP 74
CPEQC C E +CS + P+D + G L P + A L
Sbjct: 761 CPEQCTCM---ETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAV--PR-ELSALRHLT 814
Query: 75 SLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTV 134
+ L S+ L+ + ++ N + + AF GL ++ + ++V
Sbjct: 815 LIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSV 874
Query: 135 PVDVLRSLPKLTHFRL 150
P L L+H L
Sbjct: 875 PEGSFNDLTSLSHLAL 890
Score = 31.1 bits (67), Expect = 7.1
Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
Query: 299 IRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 358
+R +P N+ L L RN + + + G L L L N V+ + F DL+
Sbjct: 88 LRAVPRGIPRNA--ERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLK 145
Query: 359 ALETFVMDGNELQV 372
LE ++ N+LQV
Sbjct: 146 QLERLRLNKNKLQV 159
>AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat
protein LRIG1 protein.
Length = 1093
Score = 81.0 bits (191), Expect = 7e-15
Identities = 68/219 (31%), Positives = 102/219 (46%), Gaps = 4/219 (1%)
Query: 155 NITLHANM-FANTPPLKYLELSDAKITVLPDDAFLGLN-VLEQLNVWENEIANITAGAFR 212
NIT N F + PP+K L L+ +I L AF GL+ L L + +N I + AF+
Sbjct: 174 NITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFK 233
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISN 272
L +T L LN+NRI+ + F L L + RN+ L F GL + + +
Sbjct: 234 -LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEY 292
Query: 273 NVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLR 331
N + + L AL L L +SI + + S L L L+ N L L L
Sbjct: 293 NSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLA 352
Query: 332 GQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ L+ L LS+N+++ +A F LR+L +D NE+
Sbjct: 353 ELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEI 391
Score = 80.2 bits (189), Expect = 1e-14
Identities = 73/290 (25%), Positives = 126/290 (43%), Gaps = 10/290 (3%)
Query: 40 VGARPRDYVNIDCMGGELVCAEFPEIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVK 99
+GA V++ ++ E ++ + ++ LSL + +C H +K
Sbjct: 134 LGAASSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCF---PHGPPIK 190
Query: 100 TV-VFKNAINPLNADAFKGLGITALMM-FNAGAQTTVPVDVLRSLPKLTHFRLNAGRNIT 157
+ + N I L AF GL + L + + T +PV + LP+LT LN R
Sbjct: 191 ELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRL 249
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
+ F L+ L+L I+ L D AF GL+ + L++ N + + +G+ GL +
Sbjct: 250 IEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTAL 309
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
L L+ N I + ++ +L L + N+ LD E+ L + +++S+N
Sbjct: 310 HQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISH 369
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPEE----FISNSPLRTLSLARNQLR 323
+ E F L +LR L LD + I E+ F L L+L N +R
Sbjct: 370 IAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLNLGGNAIR 419
Score = 62.1 bits (144), Expect = 3e-09
Identities = 50/202 (24%), Positives = 98/202 (48%), Gaps = 6/202 (2%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L LS K++ + F L L+++N+ N+++ I F L N+ + LN N + A+P
Sbjct: 73 LNLSYNKLSEIDPAGFEDLPNLQEVNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVP 132
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
+ L A++ +++L + N R ++ + ++ + +S N ++ F + P ++
Sbjct: 133 S-LGAASSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKE 191
Query: 292 LQLDLSSIREL---PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
L L + I L + +S S L TL L++N++ LP + +LT L L+ N +
Sbjct: 192 LNLAGNRIGTLELGAFDGLSRS-LLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRL 249
Query: 349 LAPELFADLRALETFVMDGNEL 370
+ F L +LE + N +
Sbjct: 250 IEGLTFQGLNSLEVLKLQRNNI 271
Score = 58.0 bits (134), Expect = 5e-08
Identities = 51/209 (24%), Positives = 94/209 (44%), Gaps = 2/209 (0%)
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
F + P L+ + LS K++ + F L L+++ + NE+ + + H V+ L L
Sbjct: 88 FEDLPNLQEVNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVS-LFL 146
Query: 223 NKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAV 282
N+I+++ + L L + N+ + + F I+E+ ++ N TL+
Sbjct: 147 QHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGA 206
Query: 283 FSNLP-ALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTL 341
F L +L TL+L + I +LP L L L RN++R++ +G L L L
Sbjct: 207 FDGLSRSLLTLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKL 266
Query: 342 SYNAVAELAPELFADLRALETFVMDGNEL 370
N +++L F L + ++ N L
Sbjct: 267 QRNNISKLTDGAFWGLSKMHVLHLEYNSL 295
Score = 53.6 bits (123), Expect = 1e-06
Identities = 40/144 (27%), Positives = 69/144 (47%), Gaps = 3/144 (2%)
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
+ ALP L S R LNL+ N +D F L ++QE+ +S N + A F +L
Sbjct: 59 LAALPGDL-PSWTRSLNLSY--NKLSEIDPAGFEDLPNLQEVNLSYNKLSEIDPAGFEDL 115
Query: 287 PALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAV 346
P L+ + L+ + + +P ++S + +L L N++R + S L+ L L LS N +
Sbjct: 116 PNLQEVYLNNNELTAVPSLGAASSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNI 175
Query: 347 AELAPELFADLRALETFVMDGNEL 370
E+ F ++ + GN +
Sbjct: 176 TEVRNTCFPHGPPIKELNLAGNRI 199
Score = 45.6 bits (103), Expect = 3e-04
Identities = 33/101 (32%), Positives = 50/101 (49%), Gaps = 4/101 (3%)
Query: 155 NIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANI---TAGA 210
N+T L A L L LS I+ + + AF GL L L++ NEI+ T+GA
Sbjct: 342 NLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGA 401
Query: 211 FRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
F GL +++ L+L N I+++ F L L + +SF
Sbjct: 402 FSGLDSLSKLNLGGNAIRSVQFDAFVKMKNLKELHISSDSF 442
>BC110058-1|AAI10059.1| 518|Homo sapiens leucine rich repeat
transmembrane neuronal 4 protein.
Length = 518
Score = 80.6 bits (190), Expect = 9e-15
Identities = 60/241 (24%), Positives = 109/241 (45%), Gaps = 1/241 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N+I L ++ F GL + + ++V D + + +L L++ + LH F
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
P L+ L+LS K+ L + F GL L L++ N + + F+ N+ L L
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NR+++L FA +L L + N F ++ F L +++ I + N ++ + +
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 285 NLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+L L L + I+ + P F L+ L+L N+L + + + L S+TLS
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSG 310
Query: 344 N 344
N
Sbjct: 311 N 311
Score = 72.5 bits (170), Expect = 2e-12
Identities = 56/201 (27%), Positives = 89/201 (44%), Gaps = 1/201 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L I L + F GLN L L + N I+++ AF+G+ + L L+ N+I L
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
F P L NL + N + L SE F+GL + + + +N T+ VF + L
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 292 LQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L L + +R L F L+ L L NQ + + L S+ L +N + ++
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 245
Query: 351 PELFADLRALETFVMDGNELQ 371
L +L + GN++Q
Sbjct: 246 QGLTWTWSSLHNLDLSGNDIQ 266
Score = 58.0 bits (134), Expect = 5e-08
Identities = 47/173 (27%), Positives = 72/173 (41%), Gaps = 6/173 (3%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L ++ FKGL ++ + + TVP+ V + L L R +L N FA
Sbjct: 143 NKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFA 202
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAG---AFRGLHNVTVLS 221
LK L L + + + F L L + + N I +I+ G + LHN L
Sbjct: 203 GLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHN---LD 259
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV 274
L+ N IQ + G F P L L + N + ET + I +S N+
Sbjct: 260 LSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNM 312
>BC099738-1|AAH99738.1| 518|Homo sapiens leucine rich repeat
transmembrane neuronal 4 protein.
Length = 518
Score = 80.6 bits (190), Expect = 9e-15
Identities = 60/241 (24%), Positives = 109/241 (45%), Gaps = 1/241 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N+I L ++ F GL + + ++V D + + +L L++ + LH F
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
P L+ L+LS K+ L + F GL L L++ N + + F+ N+ L L
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NR+++L FA +L L + N F ++ F L +++ I + N ++ + +
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 285 NLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+L L L + I+ + P F L+ L+L N+L + + + L S+TLS
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSG 310
Query: 344 N 344
N
Sbjct: 311 N 311
Score = 72.5 bits (170), Expect = 2e-12
Identities = 56/201 (27%), Positives = 89/201 (44%), Gaps = 1/201 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L I L + F GLN L L + N I+++ AF+G+ + L L+ N+I L
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
F P L NL + N + L SE F+GL + + + +N T+ VF + L
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 292 LQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L L + +R L F L+ L L NQ + + L S+ L +N + ++
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 245
Query: 351 PELFADLRALETFVMDGNELQ 371
L +L + GN++Q
Sbjct: 246 QGLTWTWSSLHNLDLSGNDIQ 266
Score = 58.0 bits (134), Expect = 5e-08
Identities = 47/173 (27%), Positives = 72/173 (41%), Gaps = 6/173 (3%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L ++ FKGL ++ + + TVP+ V + L L R +L N FA
Sbjct: 143 NKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFA 202
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAG---AFRGLHNVTVLS 221
LK L L + + + F L L + + N I +I+ G + LHN L
Sbjct: 203 GLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHN---LD 259
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV 274
L+ N IQ + G F P L L + N + ET + I +S N+
Sbjct: 260 LSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNM 312
>BC098301-1|AAH98301.1| 519|Homo sapiens LRRTM4 protein protein.
Length = 519
Score = 80.6 bits (190), Expect = 9e-15
Identities = 60/241 (24%), Positives = 109/241 (45%), Gaps = 1/241 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N+I L ++ F GL + + ++V D + + +L L++ + LH F
Sbjct: 72 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 131
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
P L+ L+LS K+ L + F GL L L++ N + + F+ N+ L L
Sbjct: 132 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 191
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NR+++L FA +L L + N F ++ F L +++ I + N ++ + +
Sbjct: 192 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 251
Query: 285 NLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+L L L + I+ + P F L+ L+L N+L + + + L S+TLS
Sbjct: 252 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSG 311
Query: 344 N 344
N
Sbjct: 312 N 312
Score = 72.5 bits (170), Expect = 2e-12
Identities = 56/201 (27%), Positives = 89/201 (44%), Gaps = 1/201 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L I L + F GLN L L + N I+++ AF+G+ + L L+ N+I L
Sbjct: 67 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 126
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
F P L NL + N + L SE F+GL + + + +N T+ VF + L
Sbjct: 127 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 186
Query: 292 LQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L L + +R L F L+ L L NQ + + L S+ L +N + ++
Sbjct: 187 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 246
Query: 351 PELFADLRALETFVMDGNELQ 371
L +L + GN++Q
Sbjct: 247 QGLTWTWSSLHNLDLSGNDIQ 267
Score = 58.0 bits (134), Expect = 5e-08
Identities = 47/173 (27%), Positives = 72/173 (41%), Gaps = 6/173 (3%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L ++ FKGL ++ + + TVP+ V + L L R +L N FA
Sbjct: 144 NKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFA 203
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAG---AFRGLHNVTVLS 221
LK L L + + + F L L + + N I +I+ G + LHN L
Sbjct: 204 GLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHN---LD 260
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV 274
L+ N IQ + G F P L L + N + ET + I +S N+
Sbjct: 261 LSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNM 313
>BC098267-1|AAH98267.1| 519|Homo sapiens LRRTM4 protein protein.
Length = 519
Score = 80.6 bits (190), Expect = 9e-15
Identities = 60/241 (24%), Positives = 109/241 (45%), Gaps = 1/241 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N+I L ++ F GL + + ++V D + + +L L++ + LH F
Sbjct: 72 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 131
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
P L+ L+LS K+ L + F GL L L++ N + + F+ N+ L L
Sbjct: 132 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 191
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NR+++L FA +L L + N F ++ F L +++ I + N ++ + +
Sbjct: 192 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 251
Query: 285 NLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+L L L + I+ + P F L+ L+L N+L + + + L S+TLS
Sbjct: 252 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSG 311
Query: 344 N 344
N
Sbjct: 312 N 312
Score = 72.5 bits (170), Expect = 2e-12
Identities = 56/201 (27%), Positives = 89/201 (44%), Gaps = 1/201 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L I L + F GLN L L + N I+++ AF+G+ + L L+ N+I L
Sbjct: 67 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 126
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
F P L NL + N + L SE F+GL + + + +N T+ VF + L
Sbjct: 127 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 186
Query: 292 LQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L L + +R L F L+ L L NQ + + L S+ L +N + ++
Sbjct: 187 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 246
Query: 351 PELFADLRALETFVMDGNELQ 371
L +L + GN++Q
Sbjct: 247 QGLTWTWSSLHNLDLSGNDIQ 267
Score = 58.0 bits (134), Expect = 5e-08
Identities = 47/173 (27%), Positives = 72/173 (41%), Gaps = 6/173 (3%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L ++ FKGL ++ + + TVP+ V + L L R +L N FA
Sbjct: 144 NKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFA 203
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAG---AFRGLHNVTVLS 221
LK L L + + + F L L + + N I +I+ G + LHN L
Sbjct: 204 GLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHN---LD 260
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV 274
L+ N IQ + G F P L L + N + ET + I +S N+
Sbjct: 261 LSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNM 313
>AY358324-1|AAQ88690.1| 590|Homo sapiens GFHL3075 protein.
Length = 590
Score = 80.6 bits (190), Expect = 9e-15
Identities = 60/241 (24%), Positives = 109/241 (45%), Gaps = 1/241 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N+I L ++ F GL + + ++V D + + +L L++ + LH F
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
P L+ L+LS K+ L + F GL L L++ N + + F+ N+ L L
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NR+++L FA +L L + N F ++ F L +++ I + N ++ + +
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 285 NLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+L L L + I+ + P F L+ L+L N+L + + + L S+TLS
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSG 310
Query: 344 N 344
N
Sbjct: 311 N 311
Score = 72.5 bits (170), Expect = 2e-12
Identities = 56/201 (27%), Positives = 89/201 (44%), Gaps = 1/201 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L I L + F GLN L L + N I+++ AF+G+ + L L+ N+I L
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
F P L NL + N + L SE F+GL + + + +N T+ VF + L
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 292 LQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L L + +R L F L+ L L NQ + + L S+ L +N + ++
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 245
Query: 351 PELFADLRALETFVMDGNELQ 371
L +L + GN++Q
Sbjct: 246 QGLTWTWSSLHNLDLSGNDIQ 266
Score = 58.0 bits (134), Expect = 5e-08
Identities = 47/173 (27%), Positives = 72/173 (41%), Gaps = 6/173 (3%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L ++ FKGL ++ + + TVP+ V + L L R +L N FA
Sbjct: 143 NKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFA 202
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAG---AFRGLHNVTVLS 221
LK L L + + + F L L + + N I +I+ G + LHN L
Sbjct: 203 GLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHN---LD 259
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV 274
L+ N IQ + G F P L L + N + ET + I +S N+
Sbjct: 260 LSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNM 312
>AY182030-1|AAO67551.1| 518|Homo sapiens leucine-rich repeat
transmembrane neuronal 4 protein protein.
Length = 518
Score = 80.6 bits (190), Expect = 9e-15
Identities = 60/241 (24%), Positives = 109/241 (45%), Gaps = 1/241 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N+I L ++ F GL + + ++V D + + +L L++ + LH F
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
P L+ L+LS K+ L + F GL L L++ N + + F+ N+ L L
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NR+++L FA +L L + N F ++ F L +++ I + N ++ + +
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 285 NLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+L L L + I+ + P F L+ L+L N+L + + + L S+TLS
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSG 310
Query: 344 N 344
N
Sbjct: 311 N 311
Score = 72.5 bits (170), Expect = 2e-12
Identities = 56/201 (27%), Positives = 89/201 (44%), Gaps = 1/201 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L I L + F GLN L L + N I+++ AF+G+ + L L+ N+I L
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
F P L NL + N + L SE F+GL + + + +N T+ VF + L
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 292 LQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L L + +R L F L+ L L NQ + + L S+ L +N + ++
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 245
Query: 351 PELFADLRALETFVMDGNELQ 371
L +L + GN++Q
Sbjct: 246 QGLTWTWSSLHNLDLSGNDIQ 266
Score = 58.0 bits (134), Expect = 5e-08
Identities = 47/173 (27%), Positives = 72/173 (41%), Gaps = 6/173 (3%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L ++ FKGL ++ + + TVP+ V + L L R +L N FA
Sbjct: 143 NKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFA 202
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAG---AFRGLHNVTVLS 221
LK L L + + + F L L + + N I +I+ G + LHN L
Sbjct: 203 GLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHN---LD 259
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV 274
L+ N IQ + G F P L L + N + ET + I +S N+
Sbjct: 260 LSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNM 312
>AK126961-1|BAC86764.1| 518|Homo sapiens protein ( Homo sapiens
cDNA FLJ45014 fis, clone BRAWH3014609. ).
Length = 518
Score = 80.6 bits (190), Expect = 9e-15
Identities = 60/241 (24%), Positives = 109/241 (45%), Gaps = 1/241 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N+I L ++ F GL + + ++V D + + +L L++ + LH F
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
P L+ L+LS K+ L + F GL L L++ N + + F+ N+ L L
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NR+++L FA +L L + N F ++ F L +++ I + N ++ + +
Sbjct: 191 NRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTW 250
Query: 285 NLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+L L L + I+ + P F L+ L+L N+L + + + L S+TLS
Sbjct: 251 TWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSG 310
Query: 344 N 344
N
Sbjct: 311 N 311
Score = 72.5 bits (170), Expect = 2e-12
Identities = 56/201 (27%), Positives = 89/201 (44%), Gaps = 1/201 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L I L + F GLN L L + N I+++ AF+G+ + L L+ N+I L
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
F P L NL + N + L SE F+GL + + + +N T+ VF + L
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 292 LQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L L + +R L F L+ L L NQ + + L S+ L +N + ++
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 245
Query: 351 PELFADLRALETFVMDGNELQ 371
L +L + GN++Q
Sbjct: 246 QGLTWTWSSLHNLDLSGNDIQ 266
Score = 58.0 bits (134), Expect = 5e-08
Identities = 47/173 (27%), Positives = 72/173 (41%), Gaps = 6/173 (3%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L ++ FKGL ++ + + TVP+ V + L L R +L N FA
Sbjct: 143 NKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFA 202
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAG---AFRGLHNVTVLS 221
LK L L + + + F L L + + N I +I+ G + LHN L
Sbjct: 203 GLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHN---LD 259
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV 274
L+ N IQ + G F P L L + N + ET + I +S N+
Sbjct: 260 LSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNM 312
>AY358312-1|AAQ88679.1| 716|Homo sapiens NLRR protein.
Length = 716
Score = 79.8 bits (188), Expect = 2e-14
Identities = 65/265 (24%), Positives = 124/265 (46%), Gaps = 7/265 (2%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLS--CLLQKVHAEDVKTVVFKNAINPLNADAFKGLGIT 121
E+ TQL +L L E + ++ CL + +++ + N I+ ++A AF GL
Sbjct: 112 EVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQEL--YINHNQISTISAHAFAGLKNL 169
Query: 122 ALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITV 181
+ N+ + S P L + I + F L+ L L+ +T
Sbjct: 170 LRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTD 229
Query: 182 LPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRL 241
+P +A +GL+ LE L+ ++N++ + A + + N+ L LNKN I + G F + RL
Sbjct: 230 IPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRL 289
Query: 242 LNLTMMR-NSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPALRTLQLDLSSI 299
L + +D L + +++ +NN L+ + F ++PAL +L L+ +++
Sbjct: 290 KELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNAL 349
Query: 300 RELPEEFISNSP-LRTLSLARNQLR 323
+ ++ + + P LR +S+ N LR
Sbjct: 350 NAIYQKTVESLPNLREISIHSNPLR 374
Score = 67.3 bits (157), Expect = 9e-11
Identities = 50/208 (24%), Positives = 95/208 (45%), Gaps = 1/208 (0%)
Query: 136 VDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQ 195
VD L+ L LT + + AN L L L + +IT + D L+ L++
Sbjct: 88 VDELQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQE 147
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L + N+I+ I+A AF GL N+ L LN N+++ + + F STP L L + N +
Sbjct: 148 LYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGIL 207
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRT 314
F+ L +++ + ++ + L +L +L + + ++P+ + P L+
Sbjct: 208 DMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKF 267
Query: 315 LSLARNQLRVLPRSVLRGQTQLTSLTLS 342
L L +N + + + +L L ++
Sbjct: 268 LDLNKNPIHKIQEGDFKNMLRLKELGIN 295
>AB074161-1|BAE45733.1| 716|Homo sapiens neuronal leucine-rich
repeat protein-1 protein.
Length = 716
Score = 79.8 bits (188), Expect = 2e-14
Identities = 65/265 (24%), Positives = 124/265 (46%), Gaps = 7/265 (2%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLS--CLLQKVHAEDVKTVVFKNAINPLNADAFKGLGIT 121
E+ TQL +L L E + ++ CL + +++ + N I+ ++A AF GL
Sbjct: 112 EVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQEL--YINHNQISTISAHAFAGLKNL 169
Query: 122 ALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITV 181
+ N+ + S P L + I + F L+ L L+ +T
Sbjct: 170 LRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTD 229
Query: 182 LPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRL 241
+P +A +GL+ LE L+ ++N++ + A + + N+ L LNKN I + G F + RL
Sbjct: 230 IPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRL 289
Query: 242 LNLTMMR-NSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPALRTLQLDLSSI 299
L + +D L + +++ +NN L+ + F ++PAL +L L+ +++
Sbjct: 290 KELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNAL 349
Query: 300 RELPEEFISNSP-LRTLSLARNQLR 323
+ ++ + + P LR +S+ N LR
Sbjct: 350 NAIYQKTVESLPNLREISIHSNPLR 374
Score = 67.3 bits (157), Expect = 9e-11
Identities = 50/208 (24%), Positives = 95/208 (45%), Gaps = 1/208 (0%)
Query: 136 VDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQ 195
VD L+ L LT + + AN L L L + +IT + D L+ L++
Sbjct: 88 VDELQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQE 147
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L + N+I+ I+A AF GL N+ L LN N+++ + + F STP L L + N +
Sbjct: 148 LYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGIL 207
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRT 314
F+ L +++ + ++ + L +L +L + + ++P+ + P L+
Sbjct: 208 DMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKF 267
Query: 315 LSLARNQLRVLPRSVLRGQTQLTSLTLS 342
L L +N + + + +L L ++
Sbjct: 268 LDLNKNPIHKIQEGDFKNMLRLKELGIN 295
>AB040930-1|BAA96021.1| 730|Homo sapiens KIAA1497 protein protein.
Length = 730
Score = 79.8 bits (188), Expect = 2e-14
Identities = 65/265 (24%), Positives = 124/265 (46%), Gaps = 7/265 (2%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLS--CLLQKVHAEDVKTVVFKNAINPLNADAFKGLGIT 121
E+ TQL +L L E + ++ CL + +++ + N I+ ++A AF GL
Sbjct: 126 EVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQEL--YINHNQISTISAHAFAGLKNL 183
Query: 122 ALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITV 181
+ N+ + S P L + I + F L+ L L+ +T
Sbjct: 184 LRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTD 243
Query: 182 LPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRL 241
+P +A +GL+ LE L+ ++N++ + A + + N+ L LNKN I + G F + RL
Sbjct: 244 IPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRL 303
Query: 242 LNLTMMR-NSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPALRTLQLDLSSI 299
L + +D L + +++ +NN L+ + F ++PAL +L L+ +++
Sbjct: 304 KELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNAL 363
Query: 300 RELPEEFISNSP-LRTLSLARNQLR 323
+ ++ + + P LR +S+ N LR
Sbjct: 364 NAIYQKTVESLPNLREISIHSNPLR 388
Score = 67.3 bits (157), Expect = 9e-11
Identities = 50/208 (24%), Positives = 95/208 (45%), Gaps = 1/208 (0%)
Query: 136 VDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQ 195
VD L+ L LT + + AN L L L + +IT + D L+ L++
Sbjct: 102 VDELQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQE 161
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L + N+I+ I+A AF GL N+ L LN N+++ + + F STP L L + N +
Sbjct: 162 LYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGIL 221
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRT 314
F+ L +++ + ++ + L +L +L + + ++P+ + P L+
Sbjct: 222 DMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKF 281
Query: 315 LSLARNQLRVLPRSVLRGQTQLTSLTLS 342
L L +N + + + +L L ++
Sbjct: 282 LDLNKNPIHKIQEGDFKNMLRLKELGIN 309
>BC111067-1|AAI11068.1| 513|Homo sapiens leucine rich repeat
containing 24 protein.
Length = 513
Score = 79.4 bits (187), Expect = 2e-14
Identities = 52/152 (34%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
+ L + +N IA + GA L + L L+ N ++AL AG F + PRLL L + N R
Sbjct: 53 QTLFLQDNNIARLEPGALAPLAALRRLYLHNNSLRALEAGAFRAQPRLLELALTSNRLRG 112
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPL 312
L S F GL ++ + ++ N L + F +LP L+ L L +SI L ++ ++ S L
Sbjct: 113 LRSGAFVGLAQLRVLYLAGNQLARLLDFTFLHLPRLQELHLQENSIELLEDQALAGLSSL 172
Query: 313 RTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
L L+RNQL + R L+ L L L+ N
Sbjct: 173 ALLDLSRNQLGTISREALQPLASLQVLRLTEN 204
Score = 59.7 bits (138), Expect = 2e-08
Identities = 43/153 (28%), Positives = 68/153 (44%), Gaps = 2/153 (1%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P + L L D I L A L L +L + N + + AGAFR + L+L NR
Sbjct: 50 PGTQTLFLQDNNIARLEPGALAPLAALRRLYLHNNSLRALEAGAFRAQPRLLELALTSNR 109
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
++ L +G F +L L + N L TF L +QE+ + N L++ + L
Sbjct: 110 LRGLRSGAFVGLAQLRVLYLAGNQLARLLDFTFLHLPRLQELHLQENSIELLEDQALAGL 169
Query: 287 PALRTLQLDLSSIRELPEEFISNSPLRTLSLAR 319
+L L L + + + E + PL +L + R
Sbjct: 170 SSLALLDLSRNQLGTISREAL--QPLASLQVLR 200
Score = 53.6 bits (123), Expect = 1e-06
Identities = 38/137 (27%), Positives = 59/137 (43%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L A L+ L L + + L AF L +L + N + + +GAF GL +
Sbjct: 65 LEPGALAPLAALRRLYLHNNSLRALEAGAFRAQPRLLELALTSNRLRGLRSGAFVGLAQL 124
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
VL L N++ L F PRL L + NS L+ + GL + + +S N T
Sbjct: 125 RVLYLAGNQLARLLDFTFLHLPRLQELHLQENSIELLEDQALAGLSSLALLDLSRNQLGT 184
Query: 278 LKEAVFSNLPALRTLQL 294
+ L +L+ L+L
Sbjct: 185 ISREALQPLASLQVLRL 201
>AB178281-1|BAD97811.1| 513|Homo sapiens LRRC24 protein protein.
Length = 513
Score = 79.4 bits (187), Expect = 2e-14
Identities = 52/152 (34%), Positives = 79/152 (51%), Gaps = 1/152 (0%)
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
+ L + +N IA + GA L + L L+ N ++AL AG F + PRLL L + N R
Sbjct: 53 QTLFLQDNNIARLEPGALAPLAALRRLYLHNNSLRALEAGAFRAQPRLLELALTSNRLRG 112
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPL 312
L S F GL ++ + ++ N L + F +LP L+ L L +SI L ++ ++ S L
Sbjct: 113 LRSGAFVGLAQLRVLYLAGNQLARLLDFTFLHLPRLQELHLQENSIELLEDQALAGLSSL 172
Query: 313 RTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
L L+RNQL + R L+ L L L+ N
Sbjct: 173 ALLDLSRNQLGTISREALQPLASLQVLRLTEN 204
Score = 59.7 bits (138), Expect = 2e-08
Identities = 43/153 (28%), Positives = 68/153 (44%), Gaps = 2/153 (1%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P + L L D I L A L L +L + N + + AGAFR + L+L NR
Sbjct: 50 PGTQTLFLQDNNIARLEPGALAPLAALRRLYLHNNSLRALEAGAFRAQPRLLELALTSNR 109
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
++ L +G F +L L + N L TF L +QE+ + N L++ + L
Sbjct: 110 LRGLRSGAFVGLAQLRVLYLAGNQLARLLDFTFLHLPRLQELHLQENSIELLEDQALAGL 169
Query: 287 PALRTLQLDLSSIRELPEEFISNSPLRTLSLAR 319
+L L L + + + E + PL +L + R
Sbjct: 170 SSLALLDLSRNQLGTISREAL--QPLASLQVLR 200
Score = 53.6 bits (123), Expect = 1e-06
Identities = 38/137 (27%), Positives = 59/137 (43%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L A L+ L L + + L AF L +L + N + + +GAF GL +
Sbjct: 65 LEPGALAPLAALRRLYLHNNSLRALEAGAFRAQPRLLELALTSNRLRGLRSGAFVGLAQL 124
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
VL L N++ L F PRL L + NS L+ + GL + + +S N T
Sbjct: 125 RVLYLAGNQLARLLDFTFLHLPRLQELHLQENSIELLEDQALAGLSSLALLDLSRNQLGT 184
Query: 278 LKEAVFSNLPALRTLQL 294
+ L +L+ L+L
Sbjct: 185 ISREALQPLASLQVLRL 201
>BC113717-1|AAI13718.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 79.0 bits (186), Expect = 3e-14
Identities = 57/201 (28%), Positives = 87/201 (43%), Gaps = 1/201 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L + L + F GLN L L + N I+NI AF G+ + L L+ NRI
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
F L NL + N L SE FRGL + + + +N T+ +F + L
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 292 LQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L L + IR L F L+ L L NQ L ++ L +L L +N ++ +
Sbjct: 186 LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIG 245
Query: 351 PELFADLRALETFVMDGNELQ 371
+ +L+ + GNE++
Sbjct: 246 QTMSWTWSSLQRLDLSGNEIE 266
Score = 71.7 bits (168), Expect = 4e-12
Identities = 58/242 (23%), Positives = 104/242 (42%), Gaps = 2/242 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N++ L + FKGL + + + + + + +L L++ R N F
Sbjct: 71 NSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFR 130
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L+LS ++ L + F GL L L++ N + I F+ N+ +L L
Sbjct: 131 PVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGY 190
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRI++L +FA RL L + N F L+ F L +Q + + N + + +
Sbjct: 191 NRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSW 250
Query: 285 NLPALRTLQLDLSSIREL--PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS 342
+L+ L L + I P F L+ L+L N+L + + +L L ++L+
Sbjct: 251 TWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLA 310
Query: 343 YN 344
N
Sbjct: 311 GN 312
>BC113715-1|AAI13716.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 79.0 bits (186), Expect = 3e-14
Identities = 57/201 (28%), Positives = 87/201 (43%), Gaps = 1/201 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L + L + F GLN L L + N I+NI AF G+ + L L+ NRI
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
F L NL + N L SE FRGL + + + +N T+ +F + L
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 292 LQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L L + IR L F L+ L L NQ L ++ L +L L +N ++ +
Sbjct: 186 LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIG 245
Query: 351 PELFADLRALETFVMDGNELQ 371
+ +L+ + GNE++
Sbjct: 246 QTMSWTWSSLQRLDLSGNEIE 266
Score = 71.7 bits (168), Expect = 4e-12
Identities = 58/242 (23%), Positives = 104/242 (42%), Gaps = 2/242 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N++ L + FKGL + + + + + + +L L++ R N F
Sbjct: 71 NSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFR 130
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L+LS ++ L + F GL L L++ N + I F+ N+ +L L
Sbjct: 131 PVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGY 190
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRI++L +FA RL L + N F L+ F L +Q + + N + + +
Sbjct: 191 NRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSW 250
Query: 285 NLPALRTLQLDLSSIREL--PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS 342
+L+ L L + I P F L+ L+L N+L + + +L L ++L+
Sbjct: 251 TWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLA 310
Query: 343 YN 344
N
Sbjct: 311 GN 312
>BC111492-1|AAI11493.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 79.0 bits (186), Expect = 3e-14
Identities = 57/201 (28%), Positives = 87/201 (43%), Gaps = 1/201 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L + L + F GLN L L + N I+NI AF G+ + L L+ NRI
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
F L NL + N L SE FRGL + + + +N T+ +F + L
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 292 LQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L L + IR L F L+ L L NQ L ++ L +L L +N ++ +
Sbjct: 186 LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIG 245
Query: 351 PELFADLRALETFVMDGNELQ 371
+ +L+ + GNE++
Sbjct: 246 QTMSWTWSSLQRLDLSGNEIE 266
Score = 71.7 bits (168), Expect = 4e-12
Identities = 58/242 (23%), Positives = 104/242 (42%), Gaps = 2/242 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N++ L + FKGL + + + + + + +L L++ R N F
Sbjct: 71 NSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFR 130
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L+LS ++ L + F GL L L++ N + I F+ N+ +L L
Sbjct: 131 PVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGY 190
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRI++L +FA RL L + N F L+ F L +Q + + N + + +
Sbjct: 191 NRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSW 250
Query: 285 NLPALRTLQLDLSSIREL--PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS 342
+L+ L L + I P F L+ L+L N+L + + +L L ++L+
Sbjct: 251 TWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLA 310
Query: 343 YN 344
N
Sbjct: 311 GN 312
>AY358315-1|AAQ88681.1| 513|Homo sapiens GFNV803 protein.
Length = 513
Score = 79.0 bits (186), Expect = 3e-14
Identities = 57/201 (28%), Positives = 87/201 (43%), Gaps = 1/201 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L + L + F GLN L L + N I+NI AF G+ + L L+ NRI
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
F L NL + N L SE FRGL + + + +N T+ +F + L
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 292 LQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L L + IR L F L+ L L NQ L ++ L +L L +N ++ +
Sbjct: 186 LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIG 245
Query: 351 PELFADLRALETFVMDGNELQ 371
+ +L+ + GNE++
Sbjct: 246 QTMSWTWSSLQRLDLSGNEIE 266
Score = 71.7 bits (168), Expect = 4e-12
Identities = 58/242 (23%), Positives = 104/242 (42%), Gaps = 2/242 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N++ L + FKGL + + + + + + +L L++ R N F
Sbjct: 71 NSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFR 130
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L+LS ++ L + F GL L L++ N + I F+ N+ +L L
Sbjct: 131 PVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGY 190
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRI++L +FA RL L + N F L+ F L +Q + + N + + +
Sbjct: 191 NRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSW 250
Query: 285 NLPALRTLQLDLSSIREL--PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS 342
+L+ L L + I P F L+ L+L N+L + + +L L ++L+
Sbjct: 251 TWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLA 310
Query: 343 YN 344
N
Sbjct: 311 GN 312
>AY358114-1|AAQ88481.1| 606|Homo sapiens Tango hlg protein.
Length = 606
Score = 79.0 bits (186), Expect = 3e-14
Identities = 47/183 (25%), Positives = 91/183 (49%), Gaps = 1/183 (0%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
K L+LS ++ + + F+ +LE++++ +N IAN+ GAF L N+ L L NR++
Sbjct: 60 KILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKL 119
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
+P G+F L L + N L F+ L +++ +++ +N + + FS L +L
Sbjct: 120 VPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSL 179
Query: 290 RTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
L L+ ++ +P E +S+ L +L L + +P + L L + Y + +
Sbjct: 180 EQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLD 239
Query: 349 LAP 351
+ P
Sbjct: 240 MMP 242
Score = 70.5 bits (165), Expect = 9e-12
Identities = 58/212 (27%), Positives = 103/212 (48%), Gaps = 5/212 (2%)
Query: 86 LSCLLQKVHAEDVKTV-VFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPK 144
L + Q +H ++K++ V N + ++ AF GL + T VP + L L
Sbjct: 145 LDYMFQDLH--NLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRS 202
Query: 145 LTHFRLNAGRNITLHANMFANTPPLKYLELSD-AKITVLPDDAFLGLNVLEQLNVWENEI 203
L L + F LK+LE+ + ++P ++ GLN L L+V +
Sbjct: 203 LISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGLN-LTSLSVTNTNL 261
Query: 204 ANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLD 263
+ + AF+ L +T L+L+ N I + AG+F+ RL L ++ R ++ +F+GL
Sbjct: 262 STVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLR 321
Query: 264 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLD 295
++ + +S N+ TL+E VFS+ AL L ++
Sbjct: 322 FLRVLNVSQNLLETLEENVFSSPRALEVLSIN 353
Score = 69.7 bits (163), Expect = 2e-11
Identities = 65/269 (24%), Positives = 117/269 (43%), Gaps = 25/269 (9%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
KN + +N + F + + + V +L L RL R + +F
Sbjct: 66 KNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKLVPLGVF 125
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
L L++S+ KI +L D F L+ L+ L V +N++ I+ AF GL ++ L+L
Sbjct: 126 TGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQLTLE 185
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
K + A+P + L++L H++ + I NN+P+ F
Sbjct: 186 KCNLTAVPTEALSHLRSLISL-------------------HLKHLNI-NNMPV----YAF 221
Query: 284 SNLPALRTLQLDLSSIRE-LPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS 342
L L+ L++D + + +P + L +LS+ L +P + LT L LS
Sbjct: 222 KRLFHLKHLEIDYWPLLDMMPANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLS 281
Query: 343 YNAVAELAPELFADLRALETFVMDGNELQ 371
YN ++ + +F+DL L+ + G +L+
Sbjct: 282 YNPISTIEAGMFSDLIRLQELHIVGAQLR 310
Score = 65.3 bits (152), Expect = 4e-10
Identities = 67/270 (24%), Positives = 111/270 (41%), Gaps = 7/270 (2%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I + AF L + VP+ V L LT ++ + + L MF
Sbjct: 91 NIIANVEPGAFNNLFNLRSLRLKGNRLKLVPLGVFTGLSNLTKLDISENKIVILLDYMFQ 150
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
+ LK LE+ D + + AF GL LEQL + + + + A L ++ L L
Sbjct: 151 DLHNLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKH 210
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLD---SETFRGLDHIQEIKISNNVPLTLKEA 281
I +P F L +L + + + LD + + GL+ + + ++N T+
Sbjct: 211 LNINNMPVYAFKRLFHLKHLEI--DYWPLLDMMPANSLYGLN-LTSLSVTNTNLSTVPFL 267
Query: 282 VFSNLPALRTLQLDLSSIRELPEEFISNS-PLRTLSLARNQLRVLPRSVLRGQTQLTSLT 340
F +L L L L + I + S+ L+ L + QLR + +G L L
Sbjct: 268 AFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLN 327
Query: 341 LSYNAVAELAPELFADLRALETFVMDGNEL 370
+S N + L +F+ RALE ++ N L
Sbjct: 328 VSQNLLETLEENVFSSPRALEVLSINNNPL 357
>AY182028-1|AAO67549.1| 513|Homo sapiens leucine-rich repeat
transmembrane neuronal 3 protein protein.
Length = 513
Score = 79.0 bits (186), Expect = 3e-14
Identities = 57/201 (28%), Positives = 87/201 (43%), Gaps = 1/201 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L + L + F GLN L L + N I+NI AF G+ + L L+ NRI
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
F L NL + N L SE FRGL + + + +N T+ +F + L
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 292 LQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L L + IR L F L+ L L NQ L ++ L +L L +N ++ +
Sbjct: 186 LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIG 245
Query: 351 PELFADLRALETFVMDGNELQ 371
+ +L+ + GNE++
Sbjct: 246 QTMSWTWSSLQRLDLSGNEIE 266
Score = 71.7 bits (168), Expect = 4e-12
Identities = 58/242 (23%), Positives = 104/242 (42%), Gaps = 2/242 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N++ L + FKGL + + + + + + +L L++ R N F
Sbjct: 71 NSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFR 130
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L+LS ++ L + F GL L L++ N + I F+ N+ +L L
Sbjct: 131 PVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGY 190
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRI++L +FA RL L + N F L+ F L +Q + + N + + +
Sbjct: 191 NRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSW 250
Query: 285 NLPALRTLQLDLSSIREL--PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS 342
+L+ L L + I P F L+ L+L N+L + + +L L ++L+
Sbjct: 251 TWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLA 310
Query: 343 YN 344
N
Sbjct: 311 GN 312
>AL353746-1|CAC22713.1| 606|Homo sapiens leucine rich repeat
neuronal 6C protein.
Length = 606
Score = 79.0 bits (186), Expect = 3e-14
Identities = 47/183 (25%), Positives = 91/183 (49%), Gaps = 1/183 (0%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
K L+LS ++ + + F+ +LE++++ +N IAN+ GAF L N+ L L NR++
Sbjct: 60 KILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKL 119
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
+P G+F L L + N L F+ L +++ +++ +N + + FS L +L
Sbjct: 120 VPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSL 179
Query: 290 RTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
L L+ ++ +P E +S+ L +L L + +P + L L + Y + +
Sbjct: 180 EQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLD 239
Query: 349 LAP 351
+ P
Sbjct: 240 MMP 242
Score = 70.5 bits (165), Expect = 9e-12
Identities = 58/212 (27%), Positives = 103/212 (48%), Gaps = 5/212 (2%)
Query: 86 LSCLLQKVHAEDVKTV-VFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPK 144
L + Q +H ++K++ V N + ++ AF GL + T VP + L L
Sbjct: 145 LDYMFQDLH--NLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRS 202
Query: 145 LTHFRLNAGRNITLHANMFANTPPLKYLELSD-AKITVLPDDAFLGLNVLEQLNVWENEI 203
L L + F LK+LE+ + ++P ++ GLN L L+V +
Sbjct: 203 LISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGLN-LTSLSVTNTNL 261
Query: 204 ANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLD 263
+ + AF+ L +T L+L+ N I + AG+F+ RL L ++ R ++ +F+GL
Sbjct: 262 STVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLR 321
Query: 264 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLD 295
++ + +S N+ TL+E VFS+ AL L ++
Sbjct: 322 FLRVLNVSQNLLETLEENVFSSPRALEVLSIN 353
Score = 69.7 bits (163), Expect = 2e-11
Identities = 65/269 (24%), Positives = 117/269 (43%), Gaps = 25/269 (9%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
KN + +N + F + + + V +L L RL R + +F
Sbjct: 66 KNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKLVPLGVF 125
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
L L++S+ KI +L D F L+ L+ L V +N++ I+ AF GL ++ L+L
Sbjct: 126 TGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQLTLE 185
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
K + A+P + L++L H++ + I NN+P+ F
Sbjct: 186 KCNLTAVPTEALSHLRSLISL-------------------HLKHLNI-NNMPV----YAF 221
Query: 284 SNLPALRTLQLDLSSIRE-LPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS 342
L L+ L++D + + +P + L +LS+ L +P + LT L LS
Sbjct: 222 KRLFHLKHLEIDYWPLLDMMPANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLS 281
Query: 343 YNAVAELAPELFADLRALETFVMDGNELQ 371
YN ++ + +F+DL L+ + G +L+
Sbjct: 282 YNPISTIEAGMFSDLIRLQELHIVGAQLR 310
Score = 65.3 bits (152), Expect = 4e-10
Identities = 67/270 (24%), Positives = 111/270 (41%), Gaps = 7/270 (2%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I + AF L + VP+ V L LT ++ + + L MF
Sbjct: 91 NIIANVEPGAFNNLFNLRSLRLKGNRLKLVPLGVFTGLSNLTKLDISENKIVILLDYMFQ 150
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
+ LK LE+ D + + AF GL LEQL + + + + A L ++ L L
Sbjct: 151 DLHNLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKH 210
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLD---SETFRGLDHIQEIKISNNVPLTLKEA 281
I +P F L +L + + + LD + + GL+ + + ++N T+
Sbjct: 211 LNINNMPVYAFKRLFHLKHLEI--DYWPLLDMMPANSLYGLN-LTSLSVTNTNLSTVPFL 267
Query: 282 VFSNLPALRTLQLDLSSIRELPEEFISNS-PLRTLSLARNQLRVLPRSVLRGQTQLTSLT 340
F +L L L L + I + S+ L+ L + QLR + +G L L
Sbjct: 268 AFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLN 327
Query: 341 LSYNAVAELAPELFADLRALETFVMDGNEL 370
+S N + L +F+ RALE ++ N L
Sbjct: 328 VSQNLLETLEENVFSSPRALEVLSINNNPL 357
>AK056372-1|BAB71167.1| 606|Homo sapiens protein ( Homo sapiens
cDNA FLJ31810 fis, clone NT2RI2009289, weakly similar to
CARBOXYPEPTIDASE N 83 KD CHAIN. ).
Length = 606
Score = 79.0 bits (186), Expect = 3e-14
Identities = 47/183 (25%), Positives = 91/183 (49%), Gaps = 1/183 (0%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
K L+LS ++ + + F+ +LE++++ +N IAN+ GAF L N+ L L NR++
Sbjct: 60 KILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKL 119
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
+P G+F L L + N L F+ L +++ +++ +N + + FS L +L
Sbjct: 120 VPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSL 179
Query: 290 RTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
L L+ ++ +P E +S+ L +L L + +P + L L + Y + +
Sbjct: 180 EQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLD 239
Query: 349 LAP 351
+ P
Sbjct: 240 MMP 242
Score = 70.5 bits (165), Expect = 9e-12
Identities = 58/212 (27%), Positives = 103/212 (48%), Gaps = 5/212 (2%)
Query: 86 LSCLLQKVHAEDVKTV-VFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPK 144
L + Q +H ++K++ V N + ++ AF GL + T VP + L L
Sbjct: 145 LDYMFQDLH--NLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRS 202
Query: 145 LTHFRLNAGRNITLHANMFANTPPLKYLELSD-AKITVLPDDAFLGLNVLEQLNVWENEI 203
L L + F LK+LE+ + ++P ++ GLN L L+V +
Sbjct: 203 LISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGLN-LTSLSVTNTNL 261
Query: 204 ANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLD 263
+ + AF+ L +T L+L+ N I + AG+F+ RL L ++ R ++ +F+GL
Sbjct: 262 STVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLR 321
Query: 264 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLD 295
++ + +S N+ TL+E VFS+ AL L ++
Sbjct: 322 FLRVLNVSQNLLETLEENVFSSPRALEVLSIN 353
Score = 69.7 bits (163), Expect = 2e-11
Identities = 65/269 (24%), Positives = 117/269 (43%), Gaps = 25/269 (9%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
KN + +N + F + + + V +L L RL R + +F
Sbjct: 66 KNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKLVPLGVF 125
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
L L++S+ KI +L D F L+ L+ L V +N++ I+ AF GL ++ L+L
Sbjct: 126 TGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQLTLE 185
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
K + A+P + L++L H++ + I NN+P+ F
Sbjct: 186 KCNLTAVPTEALSHLRSLISL-------------------HLKHLNI-NNMPV----YAF 221
Query: 284 SNLPALRTLQLDLSSIRE-LPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS 342
L L+ L++D + + +P + L +LS+ L +P + LT L LS
Sbjct: 222 KRLFHLKHLEIDYWPLLDMMPANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLS 281
Query: 343 YNAVAELAPELFADLRALETFVMDGNELQ 371
YN ++ + +F+DL L+ + G +L+
Sbjct: 282 YNPISTIEAGMFSDLIRLQELHIVGAQLR 310
Score = 65.3 bits (152), Expect = 4e-10
Identities = 67/270 (24%), Positives = 111/270 (41%), Gaps = 7/270 (2%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I + AF L + VP+ V L LT ++ + + L MF
Sbjct: 91 NIIANVEPGAFNNLFNLRSLRLKGNRLKLVPLGVFTGLSNLTKLDISENKIVILLDYMFQ 150
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
+ LK LE+ D + + AF GL LEQL + + + + A L ++ L L
Sbjct: 151 DLHNLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKH 210
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLD---SETFRGLDHIQEIKISNNVPLTLKEA 281
I +P F L +L + + + LD + + GL+ + + ++N T+
Sbjct: 211 LNINNMPVYAFKRLFHLKHLEI--DYWPLLDMMPANSLYGLN-LTSLSVTNTNLSTVPFL 267
Query: 282 VFSNLPALRTLQLDLSSIRELPEEFISNS-PLRTLSLARNQLRVLPRSVLRGQTQLTSLT 340
F +L L L L + I + S+ L+ L + QLR + +G L L
Sbjct: 268 AFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLN 327
Query: 341 LSYNAVAELAPELFADLRALETFVMDGNEL 370
+S N + L +F+ RALE ++ N L
Sbjct: 328 VSQNLLETLEENVFSSPRALEVLSINNNPL 357
>BC011057-1|AAH11057.2| 620|Homo sapiens leucine rich repeat and Ig
domain containing 1 protein.
Length = 620
Score = 78.2 bits (184), Expect = 5e-14
Identities = 73/281 (25%), Positives = 122/281 (43%), Gaps = 9/281 (3%)
Query: 94 HAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAG 153
H E+++ + +N ++ + AF L + + +P+ V L LT ++
Sbjct: 96 HLEELE--LNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISEN 153
Query: 154 RNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRG 213
+ + L MF + LK LE+ D + + AF GLN LEQL + + + +I A
Sbjct: 154 KIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSH 213
Query: 214 LHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET---FRGLDHIQEIKI 270
LH + VL L I A+ F RL L + + + YLD+ T GL ++ + I
Sbjct: 214 LHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI--SHWPYLDTMTPNCLYGL-NLTSLSI 270
Query: 271 SNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSV 329
++ + +L LR L L + I + + L+ + L QL V+
Sbjct: 271 THCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYA 330
Query: 330 LRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
RG L L +S N + L +F + LET ++D N L
Sbjct: 331 FRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 371
Score = 73.7 bits (173), Expect = 1e-12
Identities = 39/140 (27%), Positives = 70/140 (50%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+ L+L +I L D F LE+L + EN ++ + GAF L N+ L L NR++
Sbjct: 74 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 133
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
+P G+F L L + N L F+ L +++ +++ +N + + FS L +L
Sbjct: 134 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 193
Query: 290 RTLQLDLSSIRELPEEFISN 309
L L+ ++ +P E +S+
Sbjct: 194 EQLTLEKCNLTSIPTEALSH 213
Score = 70.1 bits (164), Expect = 1e-11
Identities = 71/264 (26%), Positives = 120/264 (45%), Gaps = 28/264 (10%)
Query: 136 VDVLRSLPKLTHFRLNAGRNI--TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
V V +P T L+ G+N TL+ + FA+ P L+ LEL++ ++ + AF L L
Sbjct: 63 VAVPEGIPTETRL-LDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNL 121
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
L + N + I G F GL N+T L +++N+I L +F L +L + N Y
Sbjct: 122 RTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVY 181
Query: 254 LDSETFRGLDHIQEIKISN-NVPLTLKEAV--FSNLPALRTLQLDLSSIRE--------L 302
+ F GL+ ++++ + N+ EA+ L LR L++++IR+ L
Sbjct: 182 ISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRL 241
Query: 303 PEEFISNSP--------------LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
IS+ P L +LS+ L +P +R L L LSYN ++
Sbjct: 242 KVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIST 301
Query: 349 LAPELFADLRALETFVMDGNELQV 372
+ + +L L+ + G +L V
Sbjct: 302 IEGSMLHELLRLQEIQLVGGQLAV 325
>AY324320-1|AAQ97216.1| 620|Homo sapiens leucine-rich repeat
neuronal 6A protein.
Length = 620
Score = 78.2 bits (184), Expect = 5e-14
Identities = 73/281 (25%), Positives = 122/281 (43%), Gaps = 9/281 (3%)
Query: 94 HAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAG 153
H E+++ + +N ++ + AF L + + +P+ V L LT ++
Sbjct: 96 HLEELE--LNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISEN 153
Query: 154 RNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRG 213
+ + L MF + LK LE+ D + + AF GLN LEQL + + + +I A
Sbjct: 154 KIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSH 213
Query: 214 LHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET---FRGLDHIQEIKI 270
LH + VL L I A+ F RL L + + + YLD+ T GL ++ + I
Sbjct: 214 LHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI--SHWPYLDTMTPNCLYGL-NLTSLSI 270
Query: 271 SNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSV 329
++ + +L LR L L + I + + L+ + L QL V+
Sbjct: 271 THCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYA 330
Query: 330 LRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
RG L L +S N + L +F + LET ++D N L
Sbjct: 331 FRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 371
Score = 73.7 bits (173), Expect = 1e-12
Identities = 39/140 (27%), Positives = 70/140 (50%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+ L+L +I L D F LE+L + EN ++ + GAF L N+ L L NR++
Sbjct: 74 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 133
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
+P G+F L L + N L F+ L +++ +++ +N + + FS L +L
Sbjct: 134 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 193
Query: 290 RTLQLDLSSIRELPEEFISN 309
L L+ ++ +P E +S+
Sbjct: 194 EQLTLEKCNLTSIPTEALSH 213
Score = 70.1 bits (164), Expect = 1e-11
Identities = 71/264 (26%), Positives = 120/264 (45%), Gaps = 28/264 (10%)
Query: 136 VDVLRSLPKLTHFRLNAGRNI--TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
V V +P T L+ G+N TL+ + FA+ P L+ LEL++ ++ + AF L L
Sbjct: 63 VAVPEGIPTETRL-LDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNL 121
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
L + N + I G F GL N+T L +++N+I L +F L +L + N Y
Sbjct: 122 RTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVY 181
Query: 254 LDSETFRGLDHIQEIKISN-NVPLTLKEAV--FSNLPALRTLQLDLSSIRE--------L 302
+ F GL+ ++++ + N+ EA+ L LR L++++IR+ L
Sbjct: 182 ISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRL 241
Query: 303 PEEFISNSP--------------LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
IS+ P L +LS+ L +P +R L L LSYN ++
Sbjct: 242 KVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIST 301
Query: 349 LAPELFADLRALETFVMDGNELQV 372
+ + +L L+ + G +L V
Sbjct: 302 IEGSMLHELLRLQEIQLVGGQLAV 325
>AY250221-1|AAP82838.1| 420|Homo sapiens nogo receptor-like 3
protein.
Length = 420
Score = 78.2 bits (184), Expect = 5e-14
Identities = 66/204 (32%), Positives = 100/204 (49%), Gaps = 4/204 (1%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P + L L + I L F G N+L L ++ N ++ I G FR L + L L NR
Sbjct: 60 PSTQRLFLQNNLIRTLRPSTF-GSNLLT-LWLFSNNLSTIYPGTFRHLQALEELDLGDNR 117
Query: 227 -IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSN 285
+++L F RL +L + R L FRGL +Q + + N L L++ +F++
Sbjct: 118 HLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFAD 177
Query: 286 LPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
L L L L + +R L E F L L L N+L+ + R+ RG ++LT L L N
Sbjct: 178 LANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNN 237
Query: 345 AVAELAPELFADLRALETFVMDGN 368
++A L E ADL +LE ++ N
Sbjct: 238 SLASLPGEALADLPSLEFLRLNAN 261
Score = 71.7 bits (168), Expect = 4e-12
Identities = 49/166 (29%), Positives = 80/166 (48%), Gaps = 2/166 (1%)
Query: 157 TLHANMFANTPPLKYLELSDAK-ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLH 215
T++ F + L+ L+L D + + L D F GL L+ L+++ +++++ FRGL
Sbjct: 96 TIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLV 155
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
++ L L +N + L LFA L +L + N R L FRGL + + + N
Sbjct: 156 SLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRL 215
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARN 320
+ A F L L L L +S+ LP E +++ P L L L N
Sbjct: 216 QGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 64.5 bits (150), Expect = 6e-10
Identities = 53/155 (34%), Positives = 74/155 (47%), Gaps = 7/155 (4%)
Query: 220 LSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLK 279
+S N ++P L ST RL + N R L TF G + + SNN+ T+
Sbjct: 44 VSCQANNFSSVPLSLPPSTQRLF---LQNNLIRTLRPSTF-GSNLLTLWLFSNNLS-TIY 98
Query: 280 EAVFSNLPALRTLQL-DLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLT 337
F +L AL L L D +R L P+ F L++L L R QL LP ++ RG L
Sbjct: 99 PGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQ 158
Query: 338 SLTLSYNAVAELAPELFADLRALETFVMDGNELQV 372
L L N++ L +LFADL L + GN L++
Sbjct: 159 YLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRL 193
Score = 60.1 bits (139), Expect = 1e-08
Identities = 44/173 (25%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Query: 102 VFKNAINPLNADAFKGL-GITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHA 160
+F N ++ + F+ L + L + + ++ D + L +L L + +L
Sbjct: 89 LFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPG 148
Query: 161 NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVL 220
N+F L+YL L + + L DD F L L L + N + +T FRGL ++ L
Sbjct: 149 NIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRL 208
Query: 221 SLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L+ NR+Q + F RL L + NS L E L ++ ++++ N
Sbjct: 209 LLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 52.0 bits (119), Expect = 4e-06
Identities = 43/157 (27%), Positives = 70/157 (44%), Gaps = 2/157 (1%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS-FRYLDSETFRGLDHIQEIKISNNV 274
N+ L L N + + G F L L + N R L+ +TF+GL+ +Q + +
Sbjct: 83 NLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQ 142
Query: 275 PLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQ 333
+L +F L +L+ L L +S+ L ++ ++ + L L L N+LR+L V RG
Sbjct: 143 LSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGL 202
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L L L N + + F L L + N L
Sbjct: 203 GSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSL 239
>AL834260-1|CAD38935.1| 577|Homo sapiens hypothetical protein
protein.
Length = 577
Score = 78.2 bits (184), Expect = 5e-14
Identities = 73/281 (25%), Positives = 122/281 (43%), Gaps = 9/281 (3%)
Query: 94 HAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAG 153
H E+++ + +N ++ + AF L + + +P+ V L LT ++
Sbjct: 53 HLEELE--LNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISEN 110
Query: 154 RNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRG 213
+ + L MF + LK LE+ D + + AF GLN LEQL + + + +I A
Sbjct: 111 KIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSH 170
Query: 214 LHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET---FRGLDHIQEIKI 270
LH + VL L I A+ F RL L + + + YLD+ T GL ++ + I
Sbjct: 171 LHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI--SHWPYLDTMTPNCLYGL-NLTSLSI 227
Query: 271 SNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSV 329
++ + +L LR L L + I + + L+ + L QL V+
Sbjct: 228 THCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYA 287
Query: 330 LRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
RG L L +S N + L +F + LET ++D N L
Sbjct: 288 FRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 328
Score = 73.7 bits (173), Expect = 1e-12
Identities = 39/140 (27%), Positives = 70/140 (50%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+ L+L +I L D F LE+L + EN ++ + GAF L N+ L L NR++
Sbjct: 31 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 90
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
+P G+F L L + N L F+ L +++ +++ +N + + FS L +L
Sbjct: 91 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 150
Query: 290 RTLQLDLSSIRELPEEFISN 309
L L+ ++ +P E +S+
Sbjct: 151 EQLTLEKCNLTSIPTEALSH 170
Score = 70.1 bits (164), Expect = 1e-11
Identities = 71/264 (26%), Positives = 120/264 (45%), Gaps = 28/264 (10%)
Query: 136 VDVLRSLPKLTHFRLNAGRNI--TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
V V +P T L+ G+N TL+ + FA+ P L+ LEL++ ++ + AF L L
Sbjct: 20 VAVPEGIPTETRL-LDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNL 78
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
L + N + I G F GL N+T L +++N+I L +F L +L + N Y
Sbjct: 79 RTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVY 138
Query: 254 LDSETFRGLDHIQEIKISN-NVPLTLKEAV--FSNLPALRTLQLDLSSIRE--------L 302
+ F GL+ ++++ + N+ EA+ L LR L++++IR+ L
Sbjct: 139 ISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRL 198
Query: 303 PEEFISNSP--------------LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
IS+ P L +LS+ L +P +R L L LSYN ++
Sbjct: 199 KVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIST 258
Query: 349 LAPELFADLRALETFVMDGNELQV 372
+ + +L L+ + G +L V
Sbjct: 259 IEGSMLHELLRLQEIQLVGGQLAV 282
>AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein.
Length = 1534
Score = 78.2 bits (184), Expect = 5e-14
Identities = 46/152 (30%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
LEL+ IT + + F GL L L + EN+I + GAF + + L LN+N++ LP
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
LF + L L + N+ + + + FRG ++ +++ N ++E F L L
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRALRGLEV 185
Query: 292 LQLDLSSIRELPEEFISNSP-LRTLSLARNQL 322
L L+ ++I +P ++ P LRT L N L
Sbjct: 186 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 75.4 bits (177), Expect = 3e-13
Identities = 47/157 (29%), Positives = 84/157 (53%), Gaps = 3/157 (1%)
Query: 140 RSLPKLTH-FRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
+++P+ T LN G NIT +H N FA L+ L+L + +I + AF + LE+L
Sbjct: 57 KNIPRNTERLELN-GNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLR 115
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSE 257
+ N++ + F+ ++ L L++N IQA+P F L NL + +N ++
Sbjct: 116 LNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEG 175
Query: 258 TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
FR L ++ + ++NN T+ + F+++P LRT +L
Sbjct: 176 AFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRL 212
Score = 67.7 bits (158), Expect = 7e-11
Identities = 45/134 (33%), Positives = 64/134 (47%), Gaps = 3/134 (2%)
Query: 116 KGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELS 175
K L + LM GA D ++ L +L RLN + L +F N L L+LS
Sbjct: 85 KQLRVLQLMENQIGAVERGAFDDMKELERL---RLNRNQLHMLPELLFQNNQALSRLDLS 141
Query: 176 DAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLF 235
+ I +P AF G L+ L + +N+I+ I GAFR L + VL+LN N I +P F
Sbjct: 142 ENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSF 201
Query: 236 ASTPRLLNLTMMRN 249
P+L + N
Sbjct: 202 NHMPKLRTFRLHSN 215
Score = 67.3 bits (157), Expect = 9e-11
Identities = 40/154 (25%), Positives = 74/154 (48%), Gaps = 4/154 (2%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
T + + +QA+P + +T RL + N+ + F GL ++ +++ N
Sbjct: 43 TTVDCHGTGLQAIPKNIPRNTERL---ELNGNNITRIHKNDFAGLKQLRVLQLMENQIGA 99
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
++ F ++ L L+L+ + + LPE F +N L L L+ N ++ +PR RG T L
Sbjct: 100 VERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDL 159
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+L L N ++ + F LR LE ++ N +
Sbjct: 160 KNLRLDKNQISCIEEGAFRALRGLEVLTLNNNNI 193
Score = 63.7 bits (148), Expect = 1e-09
Identities = 42/156 (26%), Positives = 70/156 (44%), Gaps = 1/156 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L LN N I + FA +L L +M N ++ F + ++ ++++ N
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
L E +F N AL L L ++I+ +P + F + L+ L L +NQ+ + R
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRALR 181
Query: 335 QLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L LTL+ N + + F + L TF + N L
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 63.7 bits (148), Expect = 1e-09
Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 1/134 (0%)
Query: 141 SLPK-LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
+LP+ +T RL ++ F+ L+ ++LS+ +I + DAF GL L L ++
Sbjct: 306 NLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLY 365
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
N+I ++ G F GL+ + +L LN N+I + F L L++ N + L TF
Sbjct: 366 GNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTF 425
Query: 260 RGLDHIQEIKISNN 273
L IQ + ++ N
Sbjct: 426 TSLRAIQTLHLAQN 439
Score = 62.9 bits (146), Expect = 2e-09
Identities = 34/124 (27%), Positives = 68/124 (54%), Gaps = 1/124 (0%)
Query: 172 LELSDAKITVLPDDA-FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
L L++ +I++L F L L+++N+ N+++ I GAF G +V+ L L N+++++
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
+G+F L L + N + +++F GL +++ + + +N T+ F L +L
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 291 TLQL 294
TL L
Sbjct: 665 TLNL 668
Score = 60.5 bits (140), Expect = 1e-08
Identities = 41/143 (28%), Positives = 74/143 (51%), Gaps = 4/143 (2%)
Query: 153 GRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAF 211
G+ +T + AN+ ++ LEL+ K +P AF L ++++ N+IA I AF
Sbjct: 297 GKGLTAIPANLPETMTEIR-LELNGIKS--IPPGAFSPYRKLRRIDLSNNQIAEIAPDAF 353
Query: 212 RGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKIS 271
+GL ++ L L N+I LP G+F L L + N + + F+ L ++ + +
Sbjct: 354 QGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLY 413
Query: 272 NNVPLTLKEAVFSNLPALRTLQL 294
+N +L + F++L A++TL L
Sbjct: 414 DNKIQSLAKGTFTSLRAIQTLHL 436
Score = 56.0 bits (129), Expect = 2e-07
Identities = 41/152 (26%), Positives = 63/152 (41%), Gaps = 1/152 (0%)
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
E+L + N I I F GL + VL L +N+I A+ G F L L + RN
Sbjct: 64 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHM 123
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPL 312
L F+ + + +S N + F L+ L+LD + I + E F + L
Sbjct: 124 LPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRALRGL 183
Query: 313 RTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
L+L N + +P S +L + L N
Sbjct: 184 EVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 55.6 bits (128), Expect = 3e-07
Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 4/143 (2%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNITLHAN-MFANTPPLKYLELSDAKITVLPDDAFLGL 190
T +P + +S +L RLN L A MF LK + LS+ K++ + D AF G
Sbjct: 532 TKIPERIPQSTAEL---RLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGA 588
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS 250
+ +L++ N++ +I +G FRGL + L L NRI + F + L++ N
Sbjct: 589 ASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQ 648
Query: 251 FRYLDSETFRGLDHIQEIKISNN 273
+ F L + + + N
Sbjct: 649 ITTVSPGAFDTLQSLSTLNLLAN 671
Score = 55.2 bits (127), Expect = 4e-07
Identities = 46/146 (31%), Positives = 68/146 (46%), Gaps = 10/146 (6%)
Query: 116 KGLGITALMMFNAGAQTTVPVDV--LRSLPKLTHFRLNAGRNITLHANMFANTPP----- 168
+G G+TA+ T + +++ ++S+P R I L N A P
Sbjct: 296 RGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG 355
Query: 169 ---LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
L L L KIT LP F GL L+ L + N+I I AF+ L N+++LSL N
Sbjct: 356 LRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDN 415
Query: 226 RIQALPAGLFASTPRLLNLTMMRNSF 251
+IQ+L G F S + L + +N F
Sbjct: 416 KIQSLAKGTFTSLRAIQTLHLAQNPF 441
Score = 50.4 bits (115), Expect = 1e-05
Identities = 36/153 (23%), Positives = 69/153 (45%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T + N T + + L +L +L + + F + L+ L L+ ++
Sbjct: 63 TERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLH 122
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
+LP+ F L +L++ EN I I AFRG ++ L L+KN+I + G F +
Sbjct: 123 MLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRALRG 182
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L LT+ N+ + +F + ++ ++ +N
Sbjct: 183 LEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 50.0 bits (114), Expect = 1e-05
Identities = 37/116 (31%), Positives = 60/116 (51%), Gaps = 6/116 (5%)
Query: 139 LRSLPK-----LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
LR+LPK +T L+ G TL + L+ ++LS+ KI+ L + +F ++ L
Sbjct: 752 LRALPKGIPKNVTELYLD-GNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQL 810
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
L + N + I AF+GL ++ +LSL+ N I L G+FA L +L + N
Sbjct: 811 TTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGAN 866
Score = 48.8 bits (111), Expect = 3e-05
Identities = 32/129 (24%), Positives = 59/129 (45%), Gaps = 1/129 (0%)
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
+T + L N I+++P G F+ +L + + N + + F+GL + + + N
Sbjct: 311 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 370
Query: 277 TLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
L VF L L+ L L+ + I + P+ F L LSL N+++ L +
Sbjct: 371 DLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRA 430
Query: 336 LTSLTLSYN 344
+ +L L+ N
Sbjct: 431 IQTLHLAQN 439
Score = 47.6 bits (108), Expect = 8e-05
Identities = 69/280 (24%), Positives = 114/280 (40%), Gaps = 20/280 (7%)
Query: 95 AEDVKTV-VFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAG 153
A D+K + + KN I+ + AF+ L ++ N TT+PV +PKL
Sbjct: 156 ATDLKNLRLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKL-------- 207
Query: 154 RNITLHANMFANTPPLKYL-ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR 212
R LH+N L +L + + T+ G L LNV E + + +
Sbjct: 208 RTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQG 267
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISN 272
V +L+ + PA S + R + L + + + EI++
Sbjct: 268 EAGRVPTCTLSSG---SCPAMCTCSN----GIVDCRG--KGLTAIPANLPETMTEIRLEL 318
Query: 273 NVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLR 331
N ++ FS LR + L + I E+ P+ F L +L L N++ LPR V
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 378
Query: 332 GQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
G L L L+ N + + P+ F DL+ L + N++Q
Sbjct: 379 GLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQ 418
Score = 47.2 bits (107), Expect = 1e-04
Identities = 33/111 (29%), Positives = 51/111 (45%), Gaps = 3/111 (2%)
Query: 144 KLTHFR-LNAGRNIT--LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
KLTH + +N N + F + L L+ ++ + F GL+ L L +
Sbjct: 563 KLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRN 622
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
N I+ I +F GL NV +LSL N+I + G F + L L ++ N F
Sbjct: 623 NRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPF 673
Score = 45.6 bits (103), Expect = 3e-04
Identities = 25/79 (31%), Positives = 42/79 (53%)
Query: 292 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAP 351
L LD + +P + + L+ + L+ N++ L S +QLT+L LSYNA+ + P
Sbjct: 766 LYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPP 825
Query: 352 ELFADLRALETFVMDGNEL 370
F LR+L + GN++
Sbjct: 826 LAFQGLRSLRLLSLHGNDI 844
Score = 44.8 bits (101), Expect = 5e-04
Identities = 30/127 (23%), Positives = 57/127 (44%), Gaps = 2/127 (1%)
Query: 244 LTMMRNSFRYLDSE-TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL 302
L + N L++ F+ L H+++I +SNN +++ F ++ L L + + +
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 303 PE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALE 361
F LRTL L N++ + G + L+L N + ++P F L++L
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 362 TFVMDGN 368
T + N
Sbjct: 665 TLNLLAN 671
Score = 44.4 bits (100), Expect = 7e-04
Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 5/128 (3%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
TV+ + ++ALP G+ + L + N F + + ++Q + +SNN +
Sbjct: 743 TVVRCSNKHLRALPKGI---PKNVTELYLDGNQFTLVPGQ-LSTFKYLQLVDLSNNKISS 798
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
L + F+N+ L TL L ++++ +P F LR LSL N + L + T L
Sbjct: 799 LSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSL 858
Query: 337 TSLTLSYN 344
+ L + N
Sbjct: 859 SHLAIGAN 866
Score = 41.1 bits (92), Expect = 0.007
Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 1/121 (0%)
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
N I +I GAF + + L+ N+I + F L +L + N L F
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 378
Query: 261 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLAR 319
GL +Q + ++ N ++ F +L L L L + I+ L + F S ++TL LA+
Sbjct: 379 GLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQ 438
Query: 320 N 320
N
Sbjct: 439 N 439
Score = 39.9 bits (89), Expect = 0.015
Identities = 41/155 (26%), Positives = 63/155 (40%), Gaps = 11/155 (7%)
Query: 50 IDCMGGELVC--AEFPEIDTPATTQLPSLSLRECSLPPLSCL-LQKVHAEDVKTVVFKNA 106
+DC G L A PE T +L + S+PP + +K+ D+ N
Sbjct: 293 VDCRGKGLTAIPANLPETMTEIRLELNGIK----SIPPGAFSPYRKLRRIDLSN----NQ 344
Query: 107 INPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANT 166
I + DAF+GL ++ T +P V L L LNA + + + F +
Sbjct: 345 IAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDL 404
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
L L L D KI L F L ++ L++ +N
Sbjct: 405 QNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 439
Score = 36.7 bits (81), Expect = 0.14
Identities = 28/110 (25%), Positives = 50/110 (45%)
Query: 116 KGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELS 175
KG+ ++ G Q T+ L + L L+ + +L + F N L L LS
Sbjct: 757 KGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILS 816
Query: 176 DAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
+ +P AF GL L L++ N+I+ + G F + +++ L++ N
Sbjct: 817 YNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGAN 866
Score = 36.3 bits (80), Expect = 0.19
Identities = 26/107 (24%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
Query: 267 EIKISNNVPLTLKEA--VFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLR 323
E++++NN +++ EA +F L L+ + L + + E+ + F + + L L NQL
Sbjct: 544 ELRLNNN-EISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLE 602
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ + RG L +L L N ++ + + F LR + + N++
Sbjct: 603 SIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQI 649
Score = 31.1 bits (67), Expect = 7.1
Identities = 38/191 (19%), Positives = 67/191 (35%), Gaps = 5/191 (2%)
Query: 13 SACPEQCWCTDGEELNYQCSRPSTNLIVGARPRDYVNIDCMGGELVCAEFPEIDTPATTQ 72
SACP C CT C I PR+ ++ G + + D Q
Sbjct: 32 SACPALCTCTG---TTVDCHGTGLQAIPKNIPRNTERLELNGNNI--TRIHKNDFAGLKQ 86
Query: 73 LPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQT 132
L L L E + + E + + +N ++ L F+ + + + A
Sbjct: 87 LRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQ 146
Query: 133 TVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNV 192
+P R L + RL+ + + F L+ L L++ IT +P +F +
Sbjct: 147 AIPRKAFRGATDLKNLRLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPK 206
Query: 193 LEQLNVWENEI 203
L + N +
Sbjct: 207 LRTFRLHSNHL 217
>U96769-1|AAC13410.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 77.8 bits (183), Expect = 6e-14
Identities = 63/238 (26%), Positives = 106/238 (44%), Gaps = 6/238 (2%)
Query: 139 LRSLPKLTHFR--LNAGRNI--TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLE 194
L+ +PK++ LN RN L AN F P L L L +I + AF GL L
Sbjct: 43 LQKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLI 102
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
L + N+I + AGAF L +T L L+ N++ LP GL + L L + N R L
Sbjct: 103 YLYLSHNDIRVVRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIREL 162
Query: 255 DSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLR 313
+ F+G ++ + +S N +L+ ++ L +D + + P +S +
Sbjct: 163 RAGPFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVE 222
Query: 314 TLSLARNQLRVLPRSVLRG-QTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L L+ N L+ +P + + L +L L + + + F + L+ ++ N L
Sbjct: 223 ELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRL 280
Score = 68.5 bits (160), Expect = 4e-11
Identities = 62/256 (24%), Positives = 109/256 (42%), Gaps = 5/256 (1%)
Query: 90 LQKVHAEDVKTVVF---KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLT 146
LQK+ KT + +N L A++F+ + + V R L +L
Sbjct: 43 LQKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLI 102
Query: 147 HFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANI 206
+ L+ + A F + L YL L K+T LP L L L + N+I +
Sbjct: 103 YLYLSHNDIRVVRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIREL 162
Query: 207 TAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQ 266
AG F+G ++ L L++N + +L G L + RN S L ++
Sbjct: 163 RAGPFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVE 222
Query: 267 EIKISNNVPLTLKEAVFSNLPA-LRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRV 324
E+K+S+N ++ + F + L TL LD +++ + + F+ + L+ + L N+L
Sbjct: 223 ELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQ 282
Query: 325 LPRSVLRGQTQLTSLT 340
LP + + +LT
Sbjct: 283 LPSNFPFDSLETLALT 298
Score = 57.2 bits (132), Expect = 9e-08
Identities = 56/265 (21%), Positives = 108/265 (40%), Gaps = 7/265 (2%)
Query: 11 SVSACPEQCWCTDGEELNYQCSRPSTNLIVGARPR-DYVNIDCMGGELVCAEFPEIDTPA 69
+++ACP+ C C + + C + I + +N+ ++ A A
Sbjct: 19 ALAACPQNCHC-HSDLQHVICDKVGLQKIPKVSEKTKLLNLQRNNFPVLAAN----SFRA 73
Query: 70 TTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAG 129
L SL L+ C + ++ + + + + N I + A AF L + +
Sbjct: 74 MPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVVRAGAFDDLTELTYLYLDHN 133
Query: 130 AQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLG 189
T +P +L L L +LN + L A F L++L LS+ ++ L A
Sbjct: 134 KVTELPRGLLSPLVNLFILQLNNNKIRELRAGPFQGAKDLRWLYLSENALSSLQPGALDD 193
Query: 190 LNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
+ L + +V N++++ + A L V L L+ N ++++P F S R L + N
Sbjct: 194 VENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDN 253
Query: 250 -SFRYLDSETFRGLDHIQEIKISNN 273
+ F G+ ++ + + NN
Sbjct: 254 TNLEKFSDGAFLGVTTLKHVHLENN 278
Score = 39.1 bits (87), Expect = 0.027
Identities = 31/101 (30%), Positives = 47/101 (46%), Gaps = 2/101 (1%)
Query: 272 NNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVL 330
NN P+ + F +P L +L L IRE+ F L L L+ N +RV+
Sbjct: 61 NNFPVLAANS-FRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVVRAGAF 119
Query: 331 RGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
T+LT L L +N V EL L + L L ++ N+++
Sbjct: 120 DDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIR 160
>BC117276-1|AAI17277.1| 420|Homo sapiens reticulon 4 receptor-like
2 protein.
Length = 420
Score = 77.8 bits (183), Expect = 6e-14
Identities = 66/204 (32%), Positives = 100/204 (49%), Gaps = 4/204 (1%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P + L L + I L F G N+L L ++ N ++ I G FR L + L L NR
Sbjct: 60 PSTQRLFLQNNLIRTLRPGTF-GSNLLT-LWLFSNNLSTIYPGTFRHLQALEELDLGDNR 117
Query: 227 -IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSN 285
+++L F RL +L + R L FRGL +Q + + N L L++ +F++
Sbjct: 118 HLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFAD 177
Query: 286 LPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
L L L L + +R L E F L L L N+L+ + R+ RG ++LT L L N
Sbjct: 178 LANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNN 237
Query: 345 AVAELAPELFADLRALETFVMDGN 368
++A L E ADL +LE ++ N
Sbjct: 238 SLASLPGEALADLPSLEFLRLNAN 261
Score = 71.7 bits (168), Expect = 4e-12
Identities = 49/166 (29%), Positives = 80/166 (48%), Gaps = 2/166 (1%)
Query: 157 TLHANMFANTPPLKYLELSDAK-ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLH 215
T++ F + L+ L+L D + + L D F GL L+ L+++ +++++ FRGL
Sbjct: 96 TIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLV 155
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
++ L L +N + L LFA L +L + N R L FRGL + + + N
Sbjct: 156 SLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRL 215
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARN 320
+ A F L L L L +S+ LP E +++ P L L L N
Sbjct: 216 QGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 63.7 bits (148), Expect = 1e-09
Identities = 53/155 (34%), Positives = 74/155 (47%), Gaps = 7/155 (4%)
Query: 220 LSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLK 279
+S N ++P L ST RL + N R L TF G + + SNN+ T+
Sbjct: 44 VSCQANNFSSVPLSLPPSTQRLF---LQNNLIRTLRPGTF-GSNLLTLWLFSNNLS-TIY 98
Query: 280 EAVFSNLPALRTLQL-DLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLT 337
F +L AL L L D +R L P+ F L++L L R QL LP ++ RG L
Sbjct: 99 PGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQ 158
Query: 338 SLTLSYNAVAELAPELFADLRALETFVMDGNELQV 372
L L N++ L +LFADL L + GN L++
Sbjct: 159 YLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRL 193
Score = 60.1 bits (139), Expect = 1e-08
Identities = 44/173 (25%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Query: 102 VFKNAINPLNADAFKGL-GITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHA 160
+F N ++ + F+ L + L + + ++ D + L +L L + +L
Sbjct: 89 LFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPG 148
Query: 161 NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVL 220
N+F L+YL L + + L DD F L L L + N + +T FRGL ++ L
Sbjct: 149 NIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRL 208
Query: 221 SLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L+ NR+Q + F RL L + NS L E L ++ ++++ N
Sbjct: 209 LLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 54.4 bits (125), Expect = 7e-07
Identities = 48/179 (26%), Positives = 79/179 (44%), Gaps = 4/179 (2%)
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS-FR 252
++L + N I + G F N+ L L N + + G F L L + N R
Sbjct: 63 QRLFLQNNLIRTLRPGTFGS--NLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLR 120
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SP 311
L+ +TF+GL+ +Q + + +L +F L +L+ L L +S+ L ++ ++ +
Sbjct: 121 SLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLAN 180
Query: 312 LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L L L N+LR+L V RG L L L N + + F L L + N L
Sbjct: 181 LSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSL 239
>BC113673-1|AAI13674.1| 420|Homo sapiens reticulon 4 receptor-like
2 protein.
Length = 420
Score = 77.8 bits (183), Expect = 6e-14
Identities = 66/204 (32%), Positives = 100/204 (49%), Gaps = 4/204 (1%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P + L L + I L F G N+L L ++ N ++ I G FR L + L L NR
Sbjct: 60 PSTQRLFLQNNLIRTLRPGTF-GSNLLT-LWLFSNNLSTIYPGTFRHLQALEELDLGDNR 117
Query: 227 -IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSN 285
+++L F RL +L + R L FRGL +Q + + N L L++ +F++
Sbjct: 118 HLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFAD 177
Query: 286 LPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
L L L L + +R L E F L L L N+L+ + R+ RG ++LT L L N
Sbjct: 178 LANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNN 237
Query: 345 AVAELAPELFADLRALETFVMDGN 368
++A L E ADL +LE ++ N
Sbjct: 238 SLASLPGEALADLPSLEFLRLNAN 261
Score = 71.7 bits (168), Expect = 4e-12
Identities = 49/166 (29%), Positives = 80/166 (48%), Gaps = 2/166 (1%)
Query: 157 TLHANMFANTPPLKYLELSDAK-ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLH 215
T++ F + L+ L+L D + + L D F GL L+ L+++ +++++ FRGL
Sbjct: 96 TIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLV 155
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
++ L L +N + L LFA L +L + N R L FRGL + + + N
Sbjct: 156 SLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRL 215
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARN 320
+ A F L L L L +S+ LP E +++ P L L L N
Sbjct: 216 QGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 63.7 bits (148), Expect = 1e-09
Identities = 53/155 (34%), Positives = 74/155 (47%), Gaps = 7/155 (4%)
Query: 220 LSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLK 279
+S N ++P L ST RL + N R L TF G + + SNN+ T+
Sbjct: 44 VSCQANNFSSVPLSLPPSTQRLF---LQNNLIRTLRPGTF-GSNLLTLWLFSNNLS-TIY 98
Query: 280 EAVFSNLPALRTLQL-DLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLT 337
F +L AL L L D +R L P+ F L++L L R QL LP ++ RG L
Sbjct: 99 PGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQ 158
Query: 338 SLTLSYNAVAELAPELFADLRALETFVMDGNELQV 372
L L N++ L +LFADL L + GN L++
Sbjct: 159 YLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRL 193
Score = 60.1 bits (139), Expect = 1e-08
Identities = 44/173 (25%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Query: 102 VFKNAINPLNADAFKGL-GITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHA 160
+F N ++ + F+ L + L + + ++ D + L +L L + +L
Sbjct: 89 LFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPG 148
Query: 161 NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVL 220
N+F L+YL L + + L DD F L L L + N + +T FRGL ++ L
Sbjct: 149 NIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRL 208
Query: 221 SLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L+ NR+Q + F RL L + NS L E L ++ ++++ N
Sbjct: 209 LLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 54.4 bits (125), Expect = 7e-07
Identities = 48/179 (26%), Positives = 79/179 (44%), Gaps = 4/179 (2%)
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS-FR 252
++L + N I + G F N+ L L N + + G F L L + N R
Sbjct: 63 QRLFLQNNLIRTLRPGTFGS--NLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLR 120
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SP 311
L+ +TF+GL+ +Q + + +L +F L +L+ L L +S+ L ++ ++ +
Sbjct: 121 SLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLAN 180
Query: 312 LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L L L N+LR+L V RG L L L N + + F L L + N L
Sbjct: 181 LSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSL 239
>BC073974-1|AAH73974.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 77.8 bits (183), Expect = 6e-14
Identities = 63/238 (26%), Positives = 106/238 (44%), Gaps = 6/238 (2%)
Query: 139 LRSLPKLTHFR--LNAGRNI--TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLE 194
L+ +PK++ LN RN L AN F P L L L +I + AF GL L
Sbjct: 43 LQKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLI 102
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
L + N+I + AGAF L +T L L+ N++ LP GL + L L + N R L
Sbjct: 103 YLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIREL 162
Query: 255 DSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLR 313
+ F+G ++ + +S N +L+ ++ L +D + + P +S +
Sbjct: 163 RAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVE 222
Query: 314 TLSLARNQLRVLPRSVLRG-QTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L L+ N L+ +P + + L +L L + + + F + L+ ++ N L
Sbjct: 223 ELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRL 280
Score = 71.7 bits (168), Expect = 4e-12
Identities = 64/256 (25%), Positives = 110/256 (42%), Gaps = 5/256 (1%)
Query: 90 LQKVHAEDVKTVVF---KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLT 146
LQK+ KT + +N L A++F+ + + V R L +L
Sbjct: 43 LQKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLI 102
Query: 147 HFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANI 206
+ L+ L A F + L YL L K+T LP L L L + N+I +
Sbjct: 103 YLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIREL 162
Query: 207 TAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQ 266
AGAF+G ++ L L++N + +L G L + RN S L ++
Sbjct: 163 RAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVE 222
Query: 267 EIKISNNVPLTLKEAVFSNLPA-LRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRV 324
E+K+S+N ++ + F + L TL LD +++ + + F+ + L+ + L N+L
Sbjct: 223 ELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQ 282
Query: 325 LPRSVLRGQTQLTSLT 340
LP + + +LT
Sbjct: 283 LPSNFPFDSLETLALT 298
Score = 58.8 bits (136), Expect = 3e-08
Identities = 57/265 (21%), Positives = 108/265 (40%), Gaps = 7/265 (2%)
Query: 11 SVSACPEQCWCTDGEELNYQCSRPSTNLIVGARPR-DYVNIDCMGGELVCAEFPEIDTPA 69
+++ACP+ C C + + C + I + +N+ ++ A A
Sbjct: 19 ALAACPQNCHC-HSDLQHVICDKVGLQKIPKVSEKTKLLNLQRNNFPVLAAN----SFRA 73
Query: 70 TTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAG 129
L SL L+ C + ++ + + + + N I L A AF L + +
Sbjct: 74 MPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHN 133
Query: 130 AQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLG 189
T +P +L L L +LN + L A F L++L LS+ ++ L A
Sbjct: 134 KVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDD 193
Query: 190 LNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
+ L + +V N++++ + A L V L L+ N ++++P F S R L + N
Sbjct: 194 VENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDN 253
Query: 250 -SFRYLDSETFRGLDHIQEIKISNN 273
+ F G+ ++ + + NN
Sbjct: 254 TNLEKFSDGAFLGVTTLKHVHLENN 278
Score = 40.3 bits (90), Expect = 0.012
Identities = 32/101 (31%), Positives = 47/101 (46%), Gaps = 2/101 (1%)
Query: 272 NNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVL 330
NN P+ + F +P L +L L IRE+ F L L L+ N +RVL
Sbjct: 61 NNFPVLAANS-FRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAF 119
Query: 331 RGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
T+LT L L +N V EL L + L L ++ N+++
Sbjct: 120 DDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIR 160
>BC036360-1|AAH36360.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 77.8 bits (183), Expect = 6e-14
Identities = 63/238 (26%), Positives = 106/238 (44%), Gaps = 6/238 (2%)
Query: 139 LRSLPKLTHFR--LNAGRNI--TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLE 194
L+ +PK++ LN RN L AN F P L L L +I + AF GL L
Sbjct: 43 LQKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLI 102
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
L + N+I + AGAF L +T L L+ N++ LP GL + L L + N R L
Sbjct: 103 YLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIREL 162
Query: 255 DSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLR 313
+ F+G ++ + +S N +L+ ++ L +D + + P +S +
Sbjct: 163 RAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVE 222
Query: 314 TLSLARNQLRVLPRSVLRG-QTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L L+ N L+ +P + + L +L L + + + F + L+ ++ N L
Sbjct: 223 ELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRL 280
Score = 71.7 bits (168), Expect = 4e-12
Identities = 64/256 (25%), Positives = 110/256 (42%), Gaps = 5/256 (1%)
Query: 90 LQKVHAEDVKTVVF---KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLT 146
LQK+ KT + +N L A++F+ + + V R L +L
Sbjct: 43 LQKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLI 102
Query: 147 HFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANI 206
+ L+ L A F + L YL L K+T LP L L L + N+I +
Sbjct: 103 YLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIREL 162
Query: 207 TAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQ 266
AGAF+G ++ L L++N + +L G L + RN S L ++
Sbjct: 163 RAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVE 222
Query: 267 EIKISNNVPLTLKEAVFSNLPA-LRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRV 324
E+K+S+N ++ + F + L TL LD +++ + + F+ + L+ + L N+L
Sbjct: 223 ELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQ 282
Query: 325 LPRSVLRGQTQLTSLT 340
LP + + +LT
Sbjct: 283 LPSNFPFDSLETLALT 298
Score = 58.8 bits (136), Expect = 3e-08
Identities = 57/265 (21%), Positives = 108/265 (40%), Gaps = 7/265 (2%)
Query: 11 SVSACPEQCWCTDGEELNYQCSRPSTNLIVGARPR-DYVNIDCMGGELVCAEFPEIDTPA 69
+++ACP+ C C + + C + I + +N+ ++ A A
Sbjct: 19 ALAACPQNCHC-HSDLQHVICDKVGLQKIPKVSEKTKLLNLQRNNFPVLAAN----SFRA 73
Query: 70 TTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAG 129
L SL L+ C + ++ + + + + N I L A AF L + +
Sbjct: 74 MPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHN 133
Query: 130 AQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLG 189
T +P +L L L +LN + L A F L++L LS+ ++ L A
Sbjct: 134 KVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDD 193
Query: 190 LNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
+ L + +V N++++ + A L V L L+ N ++++P F S R L + N
Sbjct: 194 VENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDN 253
Query: 250 -SFRYLDSETFRGLDHIQEIKISNN 273
+ F G+ ++ + + NN
Sbjct: 254 TNLEKFSDGAFLGVTTLKHVHLENN 278
Score = 40.3 bits (90), Expect = 0.012
Identities = 32/101 (31%), Positives = 47/101 (46%), Gaps = 2/101 (1%)
Query: 272 NNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVL 330
NN P+ + F +P L +L L IRE+ F L L L+ N +RVL
Sbjct: 61 NNFPVLAANS-FRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAF 119
Query: 331 RGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
T+LT L L +N V EL L + L L ++ N+++
Sbjct: 120 DDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIR 160
>BC034947-1|AAH34947.1| 716|Homo sapiens leucine rich repeat
neuronal 1 protein.
Length = 716
Score = 77.8 bits (183), Expect = 6e-14
Identities = 64/265 (24%), Positives = 124/265 (46%), Gaps = 7/265 (2%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLS--CLLQKVHAEDVKTVVFKNAINPLNADAFKGLGIT 121
E+ TQL +L L E + ++ CL + +++ + N I+ ++A AF GL
Sbjct: 112 EVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQEL--YINHNQISTISAHAFAGLKNL 169
Query: 122 ALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITV 181
+ N+ + S P L + I + F L+ L L+ +T
Sbjct: 170 LRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTD 229
Query: 182 LPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRL 241
+P +A +GL+ LE L+ ++N++ + A + + ++ L LNKN I + G F + RL
Sbjct: 230 IPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPSLKFLDLNKNPIHKIQEGDFKNMLRL 289
Query: 242 LNLTMMR-NSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPALRTLQLDLSSI 299
L + +D L + +++ +NN L+ + F ++PAL +L L+ +++
Sbjct: 290 KELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNAL 349
Query: 300 RELPEEFISNSP-LRTLSLARNQLR 323
+ ++ + + P LR +S+ N LR
Sbjct: 350 NAIYQKTVESLPNLREISIHSNPLR 374
Score = 67.3 bits (157), Expect = 9e-11
Identities = 50/208 (24%), Positives = 95/208 (45%), Gaps = 1/208 (0%)
Query: 136 VDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQ 195
VD L+ L LT + + AN L L L + +IT + D L+ L++
Sbjct: 88 VDELQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQE 147
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L + N+I+ I+A AF GL N+ L LN N+++ + + F STP L L + N +
Sbjct: 148 LYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGIL 207
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRT 314
F+ L +++ + ++ + L +L +L + + ++P+ + P L+
Sbjct: 208 DMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPSLKF 267
Query: 315 LSLARNQLRVLPRSVLRGQTQLTSLTLS 342
L L +N + + + +L L ++
Sbjct: 268 LDLNKNPIHKIQEGDFKNMLRLKELGIN 295
>AY029183-1|AAK31796.1| 798|Homo sapiens SLIT1 isoform B protein.
Length = 798
Score = 77.8 bits (183), Expect = 6e-14
Identities = 46/152 (30%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
LEL+ IT + + F GL L L + EN+I + GAF + + L LN+N++ LP
Sbjct: 49 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 108
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
LF + L L + N+ + + + FRG ++ +++ N ++E F L L
Sbjct: 109 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 168
Query: 292 LQLDLSSIRELPEEFISNSP-LRTLSLARNQL 322
L L+ ++I +P ++ P LRT L N L
Sbjct: 169 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 75.4 bits (177), Expect = 3e-13
Identities = 47/157 (29%), Positives = 84/157 (53%), Gaps = 3/157 (1%)
Query: 140 RSLPKLTH-FRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
+++P+ T LN G NIT +H N FA L+ L+L + +I + AF + LE+L
Sbjct: 40 KNIPRNTERLELN-GNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLR 98
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSE 257
+ N++ + F+ ++ L L++N IQA+P F L NL + +N ++
Sbjct: 99 LNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEG 158
Query: 258 TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
FR L ++ + ++NN T+ + F+++P LRT +L
Sbjct: 159 AFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRL 195
Score = 67.7 bits (158), Expect = 7e-11
Identities = 45/134 (33%), Positives = 64/134 (47%), Gaps = 3/134 (2%)
Query: 116 KGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELS 175
K L + LM GA D ++ L +L RLN + L +F N L L+LS
Sbjct: 68 KQLRVLQLMENQIGAVERGAFDDMKELERL---RLNRNQLHMLPELLFQNNQALSRLDLS 124
Query: 176 DAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLF 235
+ I +P AF G L+ L + +N+I+ I GAFR L + VL+LN N I +P F
Sbjct: 125 ENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSF 184
Query: 236 ASTPRLLNLTMMRN 249
P+L + N
Sbjct: 185 NHMPKLRTFRLHSN 198
Score = 67.3 bits (157), Expect = 9e-11
Identities = 40/154 (25%), Positives = 74/154 (48%), Gaps = 4/154 (2%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
T + + +QA+P + +T RL + N+ + F GL ++ +++ N
Sbjct: 26 TTVDCHGTGLQAIPKNIPRNTERL---ELNGNNITRIHKNDFAGLKQLRVLQLMENQIGA 82
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
++ F ++ L L+L+ + + LPE F +N L L L+ N ++ +PR RG T L
Sbjct: 83 VERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDL 142
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+L L N ++ + F LR LE ++ N +
Sbjct: 143 KNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNI 176
Score = 64.1 bits (149), Expect = 8e-10
Identities = 42/156 (26%), Positives = 70/156 (44%), Gaps = 1/156 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L LN N I + FA +L L +M N ++ F + ++ ++++ N
Sbjct: 45 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 104
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
L E +F N AL L L ++I+ +P + F + L+ L L +NQ+ + R
Sbjct: 105 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 164
Query: 335 QLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L LTL+ N + + F + L TF + N L
Sbjct: 165 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 62.9 bits (146), Expect = 2e-09
Identities = 34/124 (27%), Positives = 68/124 (54%), Gaps = 1/124 (0%)
Query: 172 LELSDAKITVLPDDA-FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
L L++ +I++L F L L+++N+ N+++ I GAF G +V+ L L N+++++
Sbjct: 538 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 597
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
+G+F L L + N + +++F GL +++ + + +N T+ F L +L
Sbjct: 598 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 657
Query: 291 TLQL 294
TL L
Sbjct: 658 TLNL 661
Score = 58.0 bits (134), Expect = 5e-08
Identities = 32/101 (31%), Positives = 52/101 (51%)
Query: 173 ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
+LS+ +I + DAF GL L L ++ N+I ++ G F GL+ + +L LN N+I +
Sbjct: 332 DLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRP 391
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
F L L++ N + L TF L IQ + ++ N
Sbjct: 392 DAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 432
Score = 57.6 bits (133), Expect = 7e-08
Identities = 42/152 (27%), Positives = 63/152 (41%), Gaps = 1/152 (0%)
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
E+L + N I I F GL + VL L +N+I A+ G F L L + RN
Sbjct: 47 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHM 106
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPL 312
L F+ + + +S N + F L+ LQLD + I + E F + L
Sbjct: 107 LPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGL 166
Query: 313 RTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
L+L N + +P S +L + L N
Sbjct: 167 EVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 198
Score = 55.6 bits (128), Expect = 3e-07
Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 4/143 (2%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNITLHAN-MFANTPPLKYLELSDAKITVLPDDAFLGL 190
T +P + +S +L RLN L A MF LK + LS+ K++ + D AF G
Sbjct: 525 TKIPERIPQSTAEL---RLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGA 581
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS 250
+ +L++ N++ +I +G FRGL + L L NRI + F + L++ N
Sbjct: 582 ASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQ 641
Query: 251 FRYLDSETFRGLDHIQEIKISNN 273
+ F L + + + N
Sbjct: 642 ITTVSPGAFDTLQSLSTLNLLAN 664
Score = 52.8 bits (121), Expect = 2e-06
Identities = 29/94 (30%), Positives = 50/94 (53%)
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
N+IA I AF+GL ++ L L N+I LP G+F L L + N + + F+
Sbjct: 336 NQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQ 395
Query: 261 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
L ++ + + +N +L + F++L A++TL L
Sbjct: 396 DLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHL 429
Score = 52.0 bits (119), Expect = 4e-06
Identities = 34/89 (38%), Positives = 46/89 (51%)
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
F L L L KIT LP F GL L+ L + N+I I AF+ L N+++LSL
Sbjct: 346 FQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSL 405
Query: 223 NKNRIQALPAGLFASTPRLLNLTMMRNSF 251
N+IQ+L G F S + L + +N F
Sbjct: 406 YDNKIQSLAKGTFTSLRAIQTLHLAQNPF 434
Score = 50.8 bits (116), Expect = 8e-06
Identities = 36/153 (23%), Positives = 69/153 (45%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T + N T + + L +L +L + + F + L+ L L+ ++
Sbjct: 46 TERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLH 105
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
+LP+ F L +L++ EN I I AFRG ++ L L+KN+I + G F +
Sbjct: 106 MLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRG 165
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L LT+ N+ + +F + ++ ++ +N
Sbjct: 166 LEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 198
Score = 47.2 bits (107), Expect = 1e-04
Identities = 33/111 (29%), Positives = 51/111 (45%), Gaps = 3/111 (2%)
Query: 144 KLTHFR-LNAGRNIT--LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
KLTH + +N N + F + L L+ ++ + F GL+ L L +
Sbjct: 556 KLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRN 615
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
N I+ I +F GL NV +LSL N+I + G F + L L ++ N F
Sbjct: 616 NRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPF 666
Score = 44.8 bits (101), Expect = 5e-04
Identities = 30/127 (23%), Positives = 57/127 (44%), Gaps = 2/127 (1%)
Query: 244 LTMMRNSFRYLDSE-TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL 302
L + N L++ F+ L H+++I +SNN +++ F ++ L L + + +
Sbjct: 538 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 597
Query: 303 PE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALE 361
F LRTL L N++ + G + L+L N + ++P F L++L
Sbjct: 598 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 657
Query: 362 TFVMDGN 368
T + N
Sbjct: 658 TLNLLAN 664
Score = 39.9 bits (89), Expect = 0.015
Identities = 25/89 (28%), Positives = 40/89 (44%)
Query: 137 DVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQL 196
D + L L L + L +F L+ L L+ KI + DAF L L L
Sbjct: 344 DAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLL 403
Query: 197 NVWENEIANITAGAFRGLHNVTVLSLNKN 225
++++N+I ++ G F L + L L +N
Sbjct: 404 SLYDNKIQSLAKGTFTSLRAIQTLHLAQN 432
Score = 38.3 bits (85), Expect = 0.047
Identities = 66/281 (23%), Positives = 106/281 (37%), Gaps = 12/281 (4%)
Query: 95 AEDVKTVVF-KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAG 153
A D+K + KN I+ + AF+ L ++ N TT+PV +PKL
Sbjct: 139 ATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKL-------- 190
Query: 154 RNITLHANMFANTPPLKYL-ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR 212
R LH+N L +L + + T+ G L LNV E + + +
Sbjct: 191 RTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQG 250
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTP-RLLNLTMMRNSFRYLDSETFRGLDHIQEIKIS 271
V +L+ A+ R LT + + +E L+ I+ I
Sbjct: 251 EAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPG 310
Query: 272 NNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVL 330
P + L + I E+ P+ F L +L L N++ LPR V
Sbjct: 311 AFSPYRKLRRIRPLSFCSPCRDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVF 370
Query: 331 RGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
G L L L+ N + + P+ F DL+ L + N++Q
Sbjct: 371 GGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQ 411
Score = 37.5 bits (83), Expect = 0.082
Identities = 27/97 (27%), Positives = 41/97 (42%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I + DAF+GL ++ T +P V L L LNA + + + F
Sbjct: 336 NQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQ 395
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
+ L L L D KI L F L ++ L++ +N
Sbjct: 396 DLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 432
Score = 36.3 bits (80), Expect = 0.19
Identities = 26/107 (24%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
Query: 267 EIKISNNVPLTLKEA--VFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLR 323
E++++NN +++ EA +F L L+ + L + + E+ + F + + L L NQL
Sbjct: 537 ELRLNNN-EISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLE 595
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ + RG L +L L N ++ + + F LR + + N++
Sbjct: 596 SIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQI 642
>AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1534
Score = 77.8 bits (183), Expect = 6e-14
Identities = 46/152 (30%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
LEL+ IT + + F GL L L + EN+I + GAF + + L LN+N++ LP
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
LF + L L + N+ + + + FRG ++ +++ N ++E F L L
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 292 LQLDLSSIRELPEEFISNSP-LRTLSLARNQL 322
L L+ ++I +P ++ P LRT L N L
Sbjct: 186 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 75.4 bits (177), Expect = 3e-13
Identities = 47/157 (29%), Positives = 84/157 (53%), Gaps = 3/157 (1%)
Query: 140 RSLPKLTH-FRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
+++P+ T LN G NIT +H N FA L+ L+L + +I + AF + LE+L
Sbjct: 57 KNIPRNTERLELN-GNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLR 115
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSE 257
+ N++ + F+ ++ L L++N IQA+P F L NL + +N ++
Sbjct: 116 LNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEG 175
Query: 258 TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
FR L ++ + ++NN T+ + F+++P LRT +L
Sbjct: 176 AFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRL 212
Score = 67.7 bits (158), Expect = 7e-11
Identities = 45/134 (33%), Positives = 64/134 (47%), Gaps = 3/134 (2%)
Query: 116 KGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELS 175
K L + LM GA D ++ L +L RLN + L +F N L L+LS
Sbjct: 85 KQLRVLQLMENQIGAVERGAFDDMKELERL---RLNRNQLHMLPELLFQNNQALSRLDLS 141
Query: 176 DAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLF 235
+ I +P AF G L+ L + +N+I+ I GAFR L + VL+LN N I +P F
Sbjct: 142 ENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSF 201
Query: 236 ASTPRLLNLTMMRN 249
P+L + N
Sbjct: 202 NHMPKLRTFRLHSN 215
Score = 67.3 bits (157), Expect = 9e-11
Identities = 40/154 (25%), Positives = 74/154 (48%), Gaps = 4/154 (2%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
T + + +QA+P + +T RL + N+ + F GL ++ +++ N
Sbjct: 43 TTVDCHGTGLQAIPKNIPRNTERL---ELNGNNITRIHKNDFAGLKQLRVLQLMENQIGA 99
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
++ F ++ L L+L+ + + LPE F +N L L L+ N ++ +PR RG T L
Sbjct: 100 VERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDL 159
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+L L N ++ + F LR LE ++ N +
Sbjct: 160 KNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNI 193
Score = 64.1 bits (149), Expect = 8e-10
Identities = 42/156 (26%), Positives = 70/156 (44%), Gaps = 1/156 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L LN N I + FA +L L +M N ++ F + ++ ++++ N
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
L E +F N AL L L ++I+ +P + F + L+ L L +NQ+ + R
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 181
Query: 335 QLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L LTL+ N + + F + L TF + N L
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 63.7 bits (148), Expect = 1e-09
Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 1/134 (0%)
Query: 141 SLPK-LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
+LP+ +T RL ++ F+ L+ ++LS+ +I + DAF GL L L ++
Sbjct: 306 NLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLY 365
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
N+I ++ G F GL+ + +L LN N+I + F L L++ N + L TF
Sbjct: 366 GNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTF 425
Query: 260 RGLDHIQEIKISNN 273
L IQ + ++ N
Sbjct: 426 TSLRAIQTLHLAQN 439
Score = 62.9 bits (146), Expect = 2e-09
Identities = 34/124 (27%), Positives = 68/124 (54%), Gaps = 1/124 (0%)
Query: 172 LELSDAKITVLPDDA-FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
L L++ +I++L F L L+++N+ N+++ I GAF G +V+ L L N+++++
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
+G+F L L + N + +++F GL +++ + + +N T+ F L +L
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 291 TLQL 294
TL L
Sbjct: 665 TLNL 668
Score = 60.5 bits (140), Expect = 1e-08
Identities = 41/143 (28%), Positives = 74/143 (51%), Gaps = 4/143 (2%)
Query: 153 GRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAF 211
G+ +T + AN+ ++ LEL+ K +P AF L ++++ N+IA I AF
Sbjct: 297 GKGLTAIPANLPETMTEIR-LELNGIKS--IPPGAFSPYRKLRRIDLSNNQIAEIAPDAF 353
Query: 212 RGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKIS 271
+GL ++ L L N+I LP G+F L L + N + + F+ L ++ + +
Sbjct: 354 QGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLY 413
Query: 272 NNVPLTLKEAVFSNLPALRTLQL 294
+N +L + F++L A++TL L
Sbjct: 414 DNKIQSLAKGTFTSLRAIQTLHL 436
Score = 57.6 bits (133), Expect = 7e-08
Identities = 42/152 (27%), Positives = 63/152 (41%), Gaps = 1/152 (0%)
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
E+L + N I I F GL + VL L +N+I A+ G F L L + RN
Sbjct: 64 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHM 123
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPL 312
L F+ + + +S N + F L+ LQLD + I + E F + L
Sbjct: 124 LPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGL 183
Query: 313 RTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
L+L N + +P S +L + L N
Sbjct: 184 EVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 55.6 bits (128), Expect = 3e-07
Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 4/143 (2%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNITLHAN-MFANTPPLKYLELSDAKITVLPDDAFLGL 190
T +P + +S +L RLN L A MF LK + LS+ K++ + D AF G
Sbjct: 532 TKIPERIPQSTAEL---RLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGA 588
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS 250
+ +L++ N++ +I +G FRGL + L L NRI + F + L++ N
Sbjct: 589 ASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQ 648
Query: 251 FRYLDSETFRGLDHIQEIKISNN 273
+ F L + + + N
Sbjct: 649 ITTVSPGAFDTLQSLSTLNLLAN 671
Score = 55.2 bits (127), Expect = 4e-07
Identities = 46/146 (31%), Positives = 68/146 (46%), Gaps = 10/146 (6%)
Query: 116 KGLGITALMMFNAGAQTTVPVDV--LRSLPKLTHFRLNAGRNITLHANMFANTPP----- 168
+G G+TA+ T + +++ ++S+P R I L N A P
Sbjct: 296 RGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG 355
Query: 169 ---LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
L L L KIT LP F GL L+ L + N+I I AF+ L N+++LSL N
Sbjct: 356 LRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDN 415
Query: 226 RIQALPAGLFASTPRLLNLTMMRNSF 251
+IQ+L G F S + L + +N F
Sbjct: 416 KIQSLAKGTFTSLRAIQTLHLAQNPF 441
Score = 50.8 bits (116), Expect = 8e-06
Identities = 36/153 (23%), Positives = 69/153 (45%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T + N T + + L +L +L + + F + L+ L L+ ++
Sbjct: 63 TERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLH 122
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
+LP+ F L +L++ EN I I AFRG ++ L L+KN+I + G F +
Sbjct: 123 MLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRG 182
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L LT+ N+ + +F + ++ ++ +N
Sbjct: 183 LEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 50.0 bits (114), Expect = 1e-05
Identities = 37/116 (31%), Positives = 60/116 (51%), Gaps = 6/116 (5%)
Query: 139 LRSLPK-----LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
LR+LPK +T L+ G TL + L+ ++LS+ KI+ L + +F ++ L
Sbjct: 752 LRALPKGIPKNVTELYLD-GNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQL 810
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
L + N + I AF+GL ++ +LSL+ N I L G+FA L +L + N
Sbjct: 811 TTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGAN 866
Score = 48.8 bits (111), Expect = 3e-05
Identities = 32/129 (24%), Positives = 59/129 (45%), Gaps = 1/129 (0%)
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
+T + L N I+++P G F+ +L + + N + + F+GL + + + N
Sbjct: 311 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 370
Query: 277 TLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
L VF L L+ L L+ + I + P+ F L LSL N+++ L +
Sbjct: 371 DLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRA 430
Query: 336 LTSLTLSYN 344
+ +L L+ N
Sbjct: 431 IQTLHLAQN 439
Score = 47.6 bits (108), Expect = 8e-05
Identities = 69/280 (24%), Positives = 113/280 (40%), Gaps = 20/280 (7%)
Query: 95 AEDVKTVVF-KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAG 153
A D+K + KN I+ + AF+ L ++ N TT+PV +PKL
Sbjct: 156 ATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKL-------- 207
Query: 154 RNITLHANMFANTPPLKYL-ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR 212
R LH+N L +L + + T+ G L LNV E + + +
Sbjct: 208 RTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQG 267
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISN 272
V +L+ + PA S + R + L + + + EI++
Sbjct: 268 EAGRVPTCTLSSG---SCPAMCTCSN----GIVDCRG--KGLTAIPANLPETMTEIRLEL 318
Query: 273 NVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLR 331
N ++ FS LR + L + I E+ P+ F L +L L N++ LPR V
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 378
Query: 332 GQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
G L L L+ N + + P+ F DL+ L + N++Q
Sbjct: 379 GLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQ 418
Score = 47.2 bits (107), Expect = 1e-04
Identities = 33/111 (29%), Positives = 51/111 (45%), Gaps = 3/111 (2%)
Query: 144 KLTHFR-LNAGRNIT--LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
KLTH + +N N + F + L L+ ++ + F GL+ L L +
Sbjct: 563 KLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRN 622
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
N I+ I +F GL NV +LSL N+I + G F + L L ++ N F
Sbjct: 623 NRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPF 673
Score = 45.6 bits (103), Expect = 3e-04
Identities = 25/79 (31%), Positives = 42/79 (53%)
Query: 292 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAP 351
L LD + +P + + L+ + L+ N++ L S +QLT+L LSYNA+ + P
Sbjct: 766 LYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPP 825
Query: 352 ELFADLRALETFVMDGNEL 370
F LR+L + GN++
Sbjct: 826 LAFQGLRSLRLLSLHGNDI 844
Score = 44.8 bits (101), Expect = 5e-04
Identities = 30/127 (23%), Positives = 57/127 (44%), Gaps = 2/127 (1%)
Query: 244 LTMMRNSFRYLDSE-TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL 302
L + N L++ F+ L H+++I +SNN +++ F ++ L L + + +
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 303 PE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALE 361
F LRTL L N++ + G + L+L N + ++P F L++L
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 362 TFVMDGN 368
T + N
Sbjct: 665 TLNLLAN 671
Score = 44.4 bits (100), Expect = 7e-04
Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 5/128 (3%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
TV+ + ++ALP G+ + L + N F + + ++Q + +SNN +
Sbjct: 743 TVVRCSNKHLRALPKGI---PKNVTELYLDGNQFTLVPGQ-LSTFKYLQLVDLSNNKISS 798
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
L + F+N+ L TL L ++++ +P F LR LSL N + L + T L
Sbjct: 799 LSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSL 858
Query: 337 TSLTLSYN 344
+ L + N
Sbjct: 859 SHLAIGAN 866
Score = 41.1 bits (92), Expect = 0.007
Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 1/121 (0%)
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
N I +I GAF + + L+ N+I + F L +L + N L F
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 378
Query: 261 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLAR 319
GL +Q + ++ N ++ F +L L L L + I+ L + F S ++TL LA+
Sbjct: 379 GLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQ 438
Query: 320 N 320
N
Sbjct: 439 N 439
Score = 39.9 bits (89), Expect = 0.015
Identities = 41/155 (26%), Positives = 63/155 (40%), Gaps = 11/155 (7%)
Query: 50 IDCMGGELVC--AEFPEIDTPATTQLPSLSLRECSLPPLSCL-LQKVHAEDVKTVVFKNA 106
+DC G L A PE T +L + S+PP + +K+ D+ N
Sbjct: 293 VDCRGKGLTAIPANLPETMTEIRLELNGIK----SIPPGAFSPYRKLRRIDLSN----NQ 344
Query: 107 INPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANT 166
I + DAF+GL ++ T +P V L L LNA + + + F +
Sbjct: 345 IAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDL 404
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
L L L D KI L F L ++ L++ +N
Sbjct: 405 QNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 439
Score = 36.7 bits (81), Expect = 0.14
Identities = 28/110 (25%), Positives = 50/110 (45%)
Query: 116 KGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELS 175
KG+ ++ G Q T+ L + L L+ + +L + F N L L LS
Sbjct: 757 KGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILS 816
Query: 176 DAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
+ +P AF GL L L++ N+I+ + G F + +++ L++ N
Sbjct: 817 YNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGAN 866
Score = 36.3 bits (80), Expect = 0.19
Identities = 26/107 (24%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
Query: 267 EIKISNNVPLTLKEA--VFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLR 323
E++++NN +++ EA +F L L+ + L + + E+ + F + + L L NQL
Sbjct: 544 ELRLNNN-EISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLE 602
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ + RG L +L L N ++ + + F LR + + N++
Sbjct: 603 SIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQI 649
>AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1461
Score = 77.8 bits (183), Expect = 6e-14
Identities = 46/152 (30%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
LEL+ IT + + F GL L L + EN+I + GAF + + L LN+N++ LP
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
LF + L L + N+ + + + FRG ++ +++ N ++E F L L
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 292 LQLDLSSIRELPEEFISNSP-LRTLSLARNQL 322
L L+ ++I +P ++ P LRT L N L
Sbjct: 186 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 75.4 bits (177), Expect = 3e-13
Identities = 47/157 (29%), Positives = 84/157 (53%), Gaps = 3/157 (1%)
Query: 140 RSLPKLTH-FRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
+++P+ T LN G NIT +H N FA L+ L+L + +I + AF + LE+L
Sbjct: 57 KNIPRNTERLELN-GNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLR 115
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSE 257
+ N++ + F+ ++ L L++N IQA+P F L NL + +N ++
Sbjct: 116 LNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEG 175
Query: 258 TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
FR L ++ + ++NN T+ + F+++P LRT +L
Sbjct: 176 AFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRL 212
Score = 67.7 bits (158), Expect = 7e-11
Identities = 45/134 (33%), Positives = 64/134 (47%), Gaps = 3/134 (2%)
Query: 116 KGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELS 175
K L + LM GA D ++ L +L RLN + L +F N L L+LS
Sbjct: 85 KQLRVLQLMENQIGAVERGAFDDMKELERL---RLNRNQLHMLPELLFQNNQALSRLDLS 141
Query: 176 DAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLF 235
+ I +P AF G L+ L + +N+I+ I GAFR L + VL+LN N I +P F
Sbjct: 142 ENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSF 201
Query: 236 ASTPRLLNLTMMRN 249
P+L + N
Sbjct: 202 NHMPKLRTFRLHSN 215
Score = 67.3 bits (157), Expect = 9e-11
Identities = 40/154 (25%), Positives = 74/154 (48%), Gaps = 4/154 (2%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
T + + +QA+P + +T RL + N+ + F GL ++ +++ N
Sbjct: 43 TTVDCHGTGLQAIPKNIPRNTERL---ELNGNNITRIHKNDFAGLKQLRVLQLMENQIGA 99
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
++ F ++ L L+L+ + + LPE F +N L L L+ N ++ +PR RG T L
Sbjct: 100 VERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDL 159
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+L L N ++ + F LR LE ++ N +
Sbjct: 160 KNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNI 193
Score = 64.1 bits (149), Expect = 8e-10
Identities = 42/156 (26%), Positives = 70/156 (44%), Gaps = 1/156 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L LN N I + FA +L L +M N ++ F + ++ ++++ N
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
L E +F N AL L L ++I+ +P + F + L+ L L +NQ+ + R
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 181
Query: 335 QLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L LTL+ N + + F + L TF + N L
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 63.7 bits (148), Expect = 1e-09
Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 1/134 (0%)
Query: 141 SLPK-LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
+LP+ +T RL ++ F+ L+ ++LS+ +I + DAF GL L L ++
Sbjct: 306 NLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLY 365
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
N+I ++ G F GL+ + +L LN N+I + F L L++ N + L TF
Sbjct: 366 GNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTF 425
Query: 260 RGLDHIQEIKISNN 273
L IQ + ++ N
Sbjct: 426 TSLRAIQTLHLAQN 439
Score = 62.9 bits (146), Expect = 2e-09
Identities = 34/124 (27%), Positives = 68/124 (54%), Gaps = 1/124 (0%)
Query: 172 LELSDAKITVLPDDA-FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
L L++ +I++L F L L+++N+ N+++ I GAF G +V+ L L N+++++
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
+G+F L L + N + +++F GL +++ + + +N T+ F L +L
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 291 TLQL 294
TL L
Sbjct: 665 TLNL 668
Score = 60.5 bits (140), Expect = 1e-08
Identities = 41/143 (28%), Positives = 74/143 (51%), Gaps = 4/143 (2%)
Query: 153 GRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAF 211
G+ +T + AN+ ++ LEL+ K +P AF L ++++ N+IA I AF
Sbjct: 297 GKGLTAIPANLPETMTEIR-LELNGIKS--IPPGAFSPYRKLRRIDLSNNQIAEIAPDAF 353
Query: 212 RGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKIS 271
+GL ++ L L N+I LP G+F L L + N + + F+ L ++ + +
Sbjct: 354 QGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLY 413
Query: 272 NNVPLTLKEAVFSNLPALRTLQL 294
+N +L + F++L A++TL L
Sbjct: 414 DNKIQSLAKGTFTSLRAIQTLHL 436
Score = 57.6 bits (133), Expect = 7e-08
Identities = 42/152 (27%), Positives = 63/152 (41%), Gaps = 1/152 (0%)
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
E+L + N I I F GL + VL L +N+I A+ G F L L + RN
Sbjct: 64 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHM 123
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPL 312
L F+ + + +S N + F L+ LQLD + I + E F + L
Sbjct: 124 LPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGL 183
Query: 313 RTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
L+L N + +P S +L + L N
Sbjct: 184 EVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 55.6 bits (128), Expect = 3e-07
Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 4/143 (2%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNITLHAN-MFANTPPLKYLELSDAKITVLPDDAFLGL 190
T +P + +S +L RLN L A MF LK + LS+ K++ + D AF G
Sbjct: 532 TKIPERIPQSTAEL---RLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGA 588
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS 250
+ +L++ N++ +I +G FRGL + L L NRI + F + L++ N
Sbjct: 589 ASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQ 648
Query: 251 FRYLDSETFRGLDHIQEIKISNN 273
+ F L + + + N
Sbjct: 649 ITTVSPGAFDTLQSLSTLNLLAN 671
Score = 55.2 bits (127), Expect = 4e-07
Identities = 46/146 (31%), Positives = 68/146 (46%), Gaps = 10/146 (6%)
Query: 116 KGLGITALMMFNAGAQTTVPVDV--LRSLPKLTHFRLNAGRNITLHANMFANTPP----- 168
+G G+TA+ T + +++ ++S+P R I L N A P
Sbjct: 296 RGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG 355
Query: 169 ---LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
L L L KIT LP F GL L+ L + N+I I AF+ L N+++LSL N
Sbjct: 356 LRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDN 415
Query: 226 RIQALPAGLFASTPRLLNLTMMRNSF 251
+IQ+L G F S + L + +N F
Sbjct: 416 KIQSLAKGTFTSLRAIQTLHLAQNPF 441
Score = 50.8 bits (116), Expect = 8e-06
Identities = 36/153 (23%), Positives = 69/153 (45%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T + N T + + L +L +L + + F + L+ L L+ ++
Sbjct: 63 TERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLH 122
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
+LP+ F L +L++ EN I I AFRG ++ L L+KN+I + G F +
Sbjct: 123 MLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRG 182
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L LT+ N+ + +F + ++ ++ +N
Sbjct: 183 LEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 50.0 bits (114), Expect = 1e-05
Identities = 37/116 (31%), Positives = 60/116 (51%), Gaps = 6/116 (5%)
Query: 139 LRSLPK-----LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
LR+LPK +T L+ G TL + L+ ++LS+ KI+ L + +F ++ L
Sbjct: 752 LRALPKGIPKNVTELYLD-GNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQL 810
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
L + N + I AF+GL ++ +LSL+ N I L G+FA L +L + N
Sbjct: 811 TTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGAN 866
Score = 48.8 bits (111), Expect = 3e-05
Identities = 32/129 (24%), Positives = 59/129 (45%), Gaps = 1/129 (0%)
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
+T + L N I+++P G F+ +L + + N + + F+GL + + + N
Sbjct: 311 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 370
Query: 277 TLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
L VF L L+ L L+ + I + P+ F L LSL N+++ L +
Sbjct: 371 DLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRA 430
Query: 336 LTSLTLSYN 344
+ +L L+ N
Sbjct: 431 IQTLHLAQN 439
Score = 47.6 bits (108), Expect = 8e-05
Identities = 69/280 (24%), Positives = 113/280 (40%), Gaps = 20/280 (7%)
Query: 95 AEDVKTVVF-KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAG 153
A D+K + KN I+ + AF+ L ++ N TT+PV +PKL
Sbjct: 156 ATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKL-------- 207
Query: 154 RNITLHANMFANTPPLKYL-ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR 212
R LH+N L +L + + T+ G L LNV E + + +
Sbjct: 208 RTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQG 267
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISN 272
V +L+ + PA S + R + L + + + EI++
Sbjct: 268 EAGRVPTCTLSSG---SCPAMCTCSN----GIVDCRG--KGLTAIPANLPETMTEIRLEL 318
Query: 273 NVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLR 331
N ++ FS LR + L + I E+ P+ F L +L L N++ LPR V
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 378
Query: 332 GQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
G L L L+ N + + P+ F DL+ L + N++Q
Sbjct: 379 GLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQ 418
Score = 47.2 bits (107), Expect = 1e-04
Identities = 33/111 (29%), Positives = 51/111 (45%), Gaps = 3/111 (2%)
Query: 144 KLTHFR-LNAGRNIT--LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
KLTH + +N N + F + L L+ ++ + F GL+ L L +
Sbjct: 563 KLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRN 622
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
N I+ I +F GL NV +LSL N+I + G F + L L ++ N F
Sbjct: 623 NRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPF 673
Score = 45.6 bits (103), Expect = 3e-04
Identities = 25/79 (31%), Positives = 42/79 (53%)
Query: 292 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAP 351
L LD + +P + + L+ + L+ N++ L S +QLT+L LSYNA+ + P
Sbjct: 766 LYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPP 825
Query: 352 ELFADLRALETFVMDGNEL 370
F LR+L + GN++
Sbjct: 826 LAFQGLRSLRLLSLHGNDI 844
Score = 44.8 bits (101), Expect = 5e-04
Identities = 30/127 (23%), Positives = 57/127 (44%), Gaps = 2/127 (1%)
Query: 244 LTMMRNSFRYLDSE-TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL 302
L + N L++ F+ L H+++I +SNN +++ F ++ L L + + +
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 303 PE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALE 361
F LRTL L N++ + G + L+L N + ++P F L++L
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 362 TFVMDGN 368
T + N
Sbjct: 665 TLNLLAN 671
Score = 44.4 bits (100), Expect = 7e-04
Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 5/128 (3%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
TV+ + ++ALP G+ + L + N F + + ++Q + +SNN +
Sbjct: 743 TVVRCSNKHLRALPKGI---PKNVTELYLDGNQFTLVPGQ-LSTFKYLQLVDLSNNKISS 798
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
L + F+N+ L TL L ++++ +P F LR LSL N + L + T L
Sbjct: 799 LSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSL 858
Query: 337 TSLTLSYN 344
+ L + N
Sbjct: 859 SHLAIGAN 866
Score = 41.1 bits (92), Expect = 0.007
Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 1/121 (0%)
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
N I +I GAF + + L+ N+I + F L +L + N L F
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 378
Query: 261 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLAR 319
GL +Q + ++ N ++ F +L L L L + I+ L + F S ++TL LA+
Sbjct: 379 GLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQ 438
Query: 320 N 320
N
Sbjct: 439 N 439
Score = 39.9 bits (89), Expect = 0.015
Identities = 41/155 (26%), Positives = 63/155 (40%), Gaps = 11/155 (7%)
Query: 50 IDCMGGELVC--AEFPEIDTPATTQLPSLSLRECSLPPLSCL-LQKVHAEDVKTVVFKNA 106
+DC G L A PE T +L + S+PP + +K+ D+ N
Sbjct: 293 VDCRGKGLTAIPANLPETMTEIRLELNGIK----SIPPGAFSPYRKLRRIDLSN----NQ 344
Query: 107 INPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANT 166
I + DAF+GL ++ T +P V L L LNA + + + F +
Sbjct: 345 IAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDL 404
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
L L L D KI L F L ++ L++ +N
Sbjct: 405 QNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 439
Score = 36.7 bits (81), Expect = 0.14
Identities = 28/110 (25%), Positives = 50/110 (45%)
Query: 116 KGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELS 175
KG+ ++ G Q T+ L + L L+ + +L + F N L L LS
Sbjct: 757 KGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILS 816
Query: 176 DAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
+ +P AF GL L L++ N+I+ + G F + +++ L++ N
Sbjct: 817 YNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGAN 866
Score = 36.3 bits (80), Expect = 0.19
Identities = 26/107 (24%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
Query: 267 EIKISNNVPLTLKEA--VFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLR 323
E++++NN +++ EA +F L L+ + L + + E+ + F + + L L NQL
Sbjct: 544 ELRLNNN-EISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLE 602
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ + RG L +L L N ++ + + F LR + + N++
Sbjct: 603 SIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQI 649
>AL512424-3|CAI14257.1| 409|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 409
Score = 77.8 bits (183), Expect = 6e-14
Identities = 46/152 (30%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
LEL+ IT + + F GL L L + EN+I + GAF + + L LN+N++ LP
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
LF + L L + N+ + + + FRG ++ +++ N ++E F L L
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 292 LQLDLSSIRELPEEFISNSP-LRTLSLARNQL 322
L L+ ++I +P ++ P LRT L N L
Sbjct: 186 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 75.4 bits (177), Expect = 3e-13
Identities = 47/157 (29%), Positives = 84/157 (53%), Gaps = 3/157 (1%)
Query: 140 RSLPKLTH-FRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
+++P+ T LN G NIT +H N FA L+ L+L + +I + AF + LE+L
Sbjct: 57 KNIPRNTERLELN-GNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLR 115
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSE 257
+ N++ + F+ ++ L L++N IQA+P F L NL + +N ++
Sbjct: 116 LNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEG 175
Query: 258 TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
FR L ++ + ++NN T+ + F+++P LRT +L
Sbjct: 176 AFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRL 212
Score = 67.7 bits (158), Expect = 7e-11
Identities = 45/134 (33%), Positives = 64/134 (47%), Gaps = 3/134 (2%)
Query: 116 KGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELS 175
K L + LM GA D ++ L +L RLN + L +F N L L+LS
Sbjct: 85 KQLRVLQLMENQIGAVERGAFDDMKELERL---RLNRNQLHMLPELLFQNNQALSRLDLS 141
Query: 176 DAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLF 235
+ I +P AF G L+ L + +N+I+ I GAFR L + VL+LN N I +P F
Sbjct: 142 ENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSF 201
Query: 236 ASTPRLLNLTMMRN 249
P+L + N
Sbjct: 202 NHMPKLRTFRLHSN 215
Score = 67.3 bits (157), Expect = 9e-11
Identities = 40/154 (25%), Positives = 74/154 (48%), Gaps = 4/154 (2%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
T + + +QA+P + +T RL + N+ + F GL ++ +++ N
Sbjct: 43 TTVDCHGTGLQAIPKNIPRNTERL---ELNGNNITRIHKNDFAGLKQLRVLQLMENQIGA 99
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
++ F ++ L L+L+ + + LPE F +N L L L+ N ++ +PR RG T L
Sbjct: 100 VERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDL 159
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+L L N ++ + F LR LE ++ N +
Sbjct: 160 KNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNI 193
Score = 64.1 bits (149), Expect = 8e-10
Identities = 42/156 (26%), Positives = 70/156 (44%), Gaps = 1/156 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L LN N I + FA +L L +M N ++ F + ++ ++++ N
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
L E +F N AL L L ++I+ +P + F + L+ L L +NQ+ + R
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 181
Query: 335 QLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L LTL+ N + + F + L TF + N L
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 57.6 bits (133), Expect = 7e-08
Identities = 42/152 (27%), Positives = 63/152 (41%), Gaps = 1/152 (0%)
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
E+L + N I I F GL + VL L +N+I A+ G F L L + RN
Sbjct: 64 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHM 123
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPL 312
L F+ + + +S N + F L+ LQLD + I + E F + L
Sbjct: 124 LPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGL 183
Query: 313 RTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
L+L N + +P S +L + L N
Sbjct: 184 EVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 50.8 bits (116), Expect = 8e-06
Identities = 36/153 (23%), Positives = 69/153 (45%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T + N T + + L +L +L + + F + L+ L L+ ++
Sbjct: 63 TERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLH 122
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
+LP+ F L +L++ EN I I AFRG ++ L L+KN+I + G F +
Sbjct: 123 MLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRG 182
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L LT+ N+ + +F + ++ ++ +N
Sbjct: 183 LEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 40.7 bits (91), Expect = 0.009
Identities = 57/273 (20%), Positives = 105/273 (38%), Gaps = 15/273 (5%)
Query: 102 VFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHAN 161
+ +N I + AF + + N +P + ++ L+ L+ +
Sbjct: 92 LMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRK 151
Query: 162 MFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLS 221
F LK L+L +I+ + + AF L LE L + N I I +F + +
Sbjct: 152 AFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFR 211
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLD--HIQEIKIS-------N 272
L+ N + L + L + + + RGL+ +Q+ + S
Sbjct: 212 LHSNHLFC-DCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQGEAG 270
Query: 273 NVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFI-SNSP--LRTLSLARNQLRVLPRSV 329
VP + + PA+ T + R I +N P + + L N ++ +P
Sbjct: 271 RVPTCTLSS--GSCPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGA 328
Query: 330 LRGQTQLTSLTLSYNAVAELAPELFADLRALET 362
+L + LS N +AE+AP+ F LR+L +
Sbjct: 329 FSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNS 361
Score = 35.1 bits (77), Expect = 0.44
Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Query: 95 AEDVKTVVF-KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNA 152
A D+K + KN I+ + AF+ L ++ N TT+PV +PKL FRL++
Sbjct: 156 ATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHS 214
>AL512424-1|CAI14255.1| 782|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 782
Score = 77.8 bits (183), Expect = 6e-14
Identities = 46/152 (30%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
LEL+ IT + + F GL L L + EN+I + GAF + + L LN+N++ LP
Sbjct: 49 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 108
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
LF + L L + N+ + + + FRG ++ +++ N ++E F L L
Sbjct: 109 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 168
Query: 292 LQLDLSSIRELPEEFISNSP-LRTLSLARNQL 322
L L+ ++I +P ++ P LRT L N L
Sbjct: 169 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 75.4 bits (177), Expect = 3e-13
Identities = 47/157 (29%), Positives = 84/157 (53%), Gaps = 3/157 (1%)
Query: 140 RSLPKLTH-FRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
+++P+ T LN G NIT +H N FA L+ L+L + +I + AF + LE+L
Sbjct: 40 KNIPRNTERLELN-GNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLR 98
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSE 257
+ N++ + F+ ++ L L++N IQA+P F L NL + +N ++
Sbjct: 99 LNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEG 158
Query: 258 TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
FR L ++ + ++NN T+ + F+++P LRT +L
Sbjct: 159 AFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRL 195
Score = 67.7 bits (158), Expect = 7e-11
Identities = 45/134 (33%), Positives = 64/134 (47%), Gaps = 3/134 (2%)
Query: 116 KGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELS 175
K L + LM GA D ++ L +L RLN + L +F N L L+LS
Sbjct: 68 KQLRVLQLMENQIGAVERGAFDDMKELERL---RLNRNQLHMLPELLFQNNQALSRLDLS 124
Query: 176 DAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLF 235
+ I +P AF G L+ L + +N+I+ I GAFR L + VL+LN N I +P F
Sbjct: 125 ENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSF 184
Query: 236 ASTPRLLNLTMMRN 249
P+L + N
Sbjct: 185 NHMPKLRTFRLHSN 198
Score = 67.3 bits (157), Expect = 9e-11
Identities = 40/154 (25%), Positives = 74/154 (48%), Gaps = 4/154 (2%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
T + + +QA+P + +T RL + N+ + F GL ++ +++ N
Sbjct: 26 TTVDCHGTGLQAIPKNIPRNTERL---ELNGNNITRIHKNDFAGLKQLRVLQLMENQIGA 82
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
++ F ++ L L+L+ + + LPE F +N L L L+ N ++ +PR RG T L
Sbjct: 83 VERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDL 142
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+L L N ++ + F LR LE ++ N +
Sbjct: 143 KNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNI 176
Score = 64.1 bits (149), Expect = 8e-10
Identities = 42/156 (26%), Positives = 70/156 (44%), Gaps = 1/156 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L LN N I + FA +L L +M N ++ F + ++ ++++ N
Sbjct: 45 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 104
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
L E +F N AL L L ++I+ +P + F + L+ L L +NQ+ + R
Sbjct: 105 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 164
Query: 335 QLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L LTL+ N + + F + L TF + N L
Sbjct: 165 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 62.9 bits (146), Expect = 2e-09
Identities = 34/124 (27%), Positives = 68/124 (54%), Gaps = 1/124 (0%)
Query: 172 LELSDAKITVLPDDA-FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
L L++ +I++L F L L+++N+ N+++ I GAF G +V+ L L N+++++
Sbjct: 538 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 597
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
+G+F L L + N + +++F GL +++ + + +N T+ F L +L
Sbjct: 598 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 657
Query: 291 TLQL 294
TL L
Sbjct: 658 TLNL 661
Score = 58.0 bits (134), Expect = 5e-08
Identities = 32/101 (31%), Positives = 52/101 (51%)
Query: 173 ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
+LS+ +I + DAF GL L L ++ N+I ++ G F GL+ + +L LN N+I +
Sbjct: 332 DLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRP 391
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
F L L++ N + L TF L IQ + ++ N
Sbjct: 392 DAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 432
Score = 57.6 bits (133), Expect = 7e-08
Identities = 42/152 (27%), Positives = 63/152 (41%), Gaps = 1/152 (0%)
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
E+L + N I I F GL + VL L +N+I A+ G F L L + RN
Sbjct: 47 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHM 106
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPL 312
L F+ + + +S N + F L+ LQLD + I + E F + L
Sbjct: 107 LPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGL 166
Query: 313 RTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
L+L N + +P S +L + L N
Sbjct: 167 EVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 198
Score = 55.6 bits (128), Expect = 3e-07
Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 4/143 (2%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNITLHAN-MFANTPPLKYLELSDAKITVLPDDAFLGL 190
T +P + +S +L RLN L A MF LK + LS+ K++ + D AF G
Sbjct: 525 TKIPERIPQSTAEL---RLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGA 581
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS 250
+ +L++ N++ +I +G FRGL + L L NRI + F + L++ N
Sbjct: 582 ASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQ 641
Query: 251 FRYLDSETFRGLDHIQEIKISNN 273
+ F L + + + N
Sbjct: 642 ITTVSPGAFDTLQSLSTLNLLAN 664
Score = 52.8 bits (121), Expect = 2e-06
Identities = 29/94 (30%), Positives = 50/94 (53%)
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
N+IA I AF+GL ++ L L N+I LP G+F L L + N + + F+
Sbjct: 336 NQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQ 395
Query: 261 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
L ++ + + +N +L + F++L A++TL L
Sbjct: 396 DLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHL 429
Score = 52.0 bits (119), Expect = 4e-06
Identities = 34/89 (38%), Positives = 46/89 (51%)
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
F L L L KIT LP F GL L+ L + N+I I AF+ L N+++LSL
Sbjct: 346 FQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSL 405
Query: 223 NKNRIQALPAGLFASTPRLLNLTMMRNSF 251
N+IQ+L G F S + L + +N F
Sbjct: 406 YDNKIQSLAKGTFTSLRAIQTLHLAQNPF 434
Score = 50.8 bits (116), Expect = 8e-06
Identities = 36/153 (23%), Positives = 69/153 (45%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T + N T + + L +L +L + + F + L+ L L+ ++
Sbjct: 46 TERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLH 105
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
+LP+ F L +L++ EN I I AFRG ++ L L+KN+I + G F +
Sbjct: 106 MLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRG 165
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L LT+ N+ + +F + ++ ++ +N
Sbjct: 166 LEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 198
Score = 47.2 bits (107), Expect = 1e-04
Identities = 33/111 (29%), Positives = 51/111 (45%), Gaps = 3/111 (2%)
Query: 144 KLTHFR-LNAGRNIT--LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
KLTH + +N N + F + L L+ ++ + F GL+ L L +
Sbjct: 556 KLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRN 615
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
N I+ I +F GL NV +LSL N+I + G F + L L ++ N F
Sbjct: 616 NRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPF 666
Score = 44.8 bits (101), Expect = 5e-04
Identities = 30/127 (23%), Positives = 57/127 (44%), Gaps = 2/127 (1%)
Query: 244 LTMMRNSFRYLDSE-TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL 302
L + N L++ F+ L H+++I +SNN +++ F ++ L L + + +
Sbjct: 538 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 597
Query: 303 PE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALE 361
F LRTL L N++ + G + L+L N + ++P F L++L
Sbjct: 598 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 657
Query: 362 TFVMDGN 368
T + N
Sbjct: 658 TLNLLAN 664
Score = 39.9 bits (89), Expect = 0.015
Identities = 25/89 (28%), Positives = 40/89 (44%)
Query: 137 DVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQL 196
D + L L L + L +F L+ L L+ KI + DAF L L L
Sbjct: 344 DAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLL 403
Query: 197 NVWENEIANITAGAFRGLHNVTVLSLNKN 225
++++N+I ++ G F L + L L +N
Sbjct: 404 SLYDNKIQSLAKGTFTSLRAIQTLHLAQN 432
Score = 38.7 bits (86), Expect = 0.035
Identities = 66/281 (23%), Positives = 106/281 (37%), Gaps = 12/281 (4%)
Query: 95 AEDVKTVVF-KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAG 153
A D+K + KN I+ + AF+ L ++ N TT+PV +PKL
Sbjct: 139 ATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKL-------- 190
Query: 154 RNITLHANMFANTPPLKYL-ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR 212
R LH+N L +L + + T+ G L LNV E + + +
Sbjct: 191 RTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQG 250
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTP-RLLNLTMMRNSFRYLDSETFRGLDHIQEIKIS 271
V +L+ A+ R LT + + +E L+ I+ I
Sbjct: 251 EAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPG 310
Query: 272 NNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVL 330
P + L + I E+ P+ F L +L L N++ LPR V
Sbjct: 311 AFSPYRKLRRICPLSFCSPCRDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVF 370
Query: 331 RGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
G L L L+ N + + P+ F DL+ L + N++Q
Sbjct: 371 GGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQ 411
Score = 37.5 bits (83), Expect = 0.082
Identities = 27/97 (27%), Positives = 41/97 (42%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I + DAF+GL ++ T +P V L L LNA + + + F
Sbjct: 336 NQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQ 395
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
+ L L L D KI L F L ++ L++ +N
Sbjct: 396 DLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 432
Score = 36.3 bits (80), Expect = 0.19
Identities = 26/107 (24%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
Query: 267 EIKISNNVPLTLKEA--VFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLR 323
E++++NN +++ EA +F L L+ + L + + E+ + F + + L L NQL
Sbjct: 537 ELRLNNN-EISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLE 595
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ + RG L +L L N ++ + + F LR + + N++
Sbjct: 596 SIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQI 642
>AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1461
Score = 77.8 bits (183), Expect = 6e-14
Identities = 46/152 (30%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
LEL+ IT + + F GL L L + EN+I + GAF + + L LN+N++ LP
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
LF + L L + N+ + + + FRG ++ +++ N ++E F L L
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 292 LQLDLSSIRELPEEFISNSP-LRTLSLARNQL 322
L L+ ++I +P ++ P LRT L N L
Sbjct: 186 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 75.4 bits (177), Expect = 3e-13
Identities = 47/157 (29%), Positives = 84/157 (53%), Gaps = 3/157 (1%)
Query: 140 RSLPKLTH-FRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
+++P+ T LN G NIT +H N FA L+ L+L + +I + AF + LE+L
Sbjct: 57 KNIPRNTERLELN-GNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLR 115
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSE 257
+ N++ + F+ ++ L L++N IQA+P F L NL + +N ++
Sbjct: 116 LNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEG 175
Query: 258 TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
FR L ++ + ++NN T+ + F+++P LRT +L
Sbjct: 176 AFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRL 212
Score = 67.7 bits (158), Expect = 7e-11
Identities = 45/134 (33%), Positives = 64/134 (47%), Gaps = 3/134 (2%)
Query: 116 KGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELS 175
K L + LM GA D ++ L +L RLN + L +F N L L+LS
Sbjct: 85 KQLRVLQLMENQIGAVERGAFDDMKELERL---RLNRNQLHMLPELLFQNNQALSRLDLS 141
Query: 176 DAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLF 235
+ I +P AF G L+ L + +N+I+ I GAFR L + VL+LN N I +P F
Sbjct: 142 ENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSF 201
Query: 236 ASTPRLLNLTMMRN 249
P+L + N
Sbjct: 202 NHMPKLRTFRLHSN 215
Score = 67.3 bits (157), Expect = 9e-11
Identities = 40/154 (25%), Positives = 74/154 (48%), Gaps = 4/154 (2%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
T + + +QA+P + +T RL + N+ + F GL ++ +++ N
Sbjct: 43 TTVDCHGTGLQAIPKNIPRNTERL---ELNGNNITRIHKNDFAGLKQLRVLQLMENQIGA 99
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
++ F ++ L L+L+ + + LPE F +N L L L+ N ++ +PR RG T L
Sbjct: 100 VERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDL 159
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+L L N ++ + F LR LE ++ N +
Sbjct: 160 KNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNI 193
Score = 64.1 bits (149), Expect = 8e-10
Identities = 42/156 (26%), Positives = 70/156 (44%), Gaps = 1/156 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L LN N I + FA +L L +M N ++ F + ++ ++++ N
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
L E +F N AL L L ++I+ +P + F + L+ L L +NQ+ + R
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 181
Query: 335 QLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L LTL+ N + + F + L TF + N L
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 63.7 bits (148), Expect = 1e-09
Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 1/134 (0%)
Query: 141 SLPK-LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
+LP+ +T RL ++ F+ L+ ++LS+ +I + DAF GL L L ++
Sbjct: 306 NLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLY 365
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
N+I ++ G F GL+ + +L LN N+I + F L L++ N + L TF
Sbjct: 366 GNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTF 425
Query: 260 RGLDHIQEIKISNN 273
L IQ + ++ N
Sbjct: 426 TSLRAIQTLHLAQN 439
Score = 62.9 bits (146), Expect = 2e-09
Identities = 34/124 (27%), Positives = 68/124 (54%), Gaps = 1/124 (0%)
Query: 172 LELSDAKITVLPDDA-FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
L L++ +I++L F L L+++N+ N+++ I GAF G +V+ L L N+++++
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
+G+F L L + N + +++F GL +++ + + +N T+ F L +L
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 291 TLQL 294
TL L
Sbjct: 665 TLNL 668
Score = 60.5 bits (140), Expect = 1e-08
Identities = 41/143 (28%), Positives = 74/143 (51%), Gaps = 4/143 (2%)
Query: 153 GRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAF 211
G+ +T + AN+ ++ LEL+ K +P AF L ++++ N+IA I AF
Sbjct: 297 GKGLTAIPANLPETMTEIR-LELNGIKS--IPPGAFSPYRKLRRIDLSNNQIAEIAPDAF 353
Query: 212 RGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKIS 271
+GL ++ L L N+I LP G+F L L + N + + F+ L ++ + +
Sbjct: 354 QGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLY 413
Query: 272 NNVPLTLKEAVFSNLPALRTLQL 294
+N +L + F++L A++TL L
Sbjct: 414 DNKIQSLAKGTFTSLRAIQTLHL 436
Score = 57.6 bits (133), Expect = 7e-08
Identities = 42/152 (27%), Positives = 63/152 (41%), Gaps = 1/152 (0%)
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
E+L + N I I F GL + VL L +N+I A+ G F L L + RN
Sbjct: 64 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHM 123
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPL 312
L F+ + + +S N + F L+ LQLD + I + E F + L
Sbjct: 124 LPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGL 183
Query: 313 RTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
L+L N + +P S +L + L N
Sbjct: 184 EVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 55.6 bits (128), Expect = 3e-07
Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 4/143 (2%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNITLHAN-MFANTPPLKYLELSDAKITVLPDDAFLGL 190
T +P + +S +L RLN L A MF LK + LS+ K++ + D AF G
Sbjct: 532 TKIPERIPQSTAEL---RLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGA 588
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS 250
+ +L++ N++ +I +G FRGL + L L NRI + F + L++ N
Sbjct: 589 ASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQ 648
Query: 251 FRYLDSETFRGLDHIQEIKISNN 273
+ F L + + + N
Sbjct: 649 ITTVSPGAFDTLQSLSTLNLLAN 671
Score = 55.2 bits (127), Expect = 4e-07
Identities = 46/146 (31%), Positives = 68/146 (46%), Gaps = 10/146 (6%)
Query: 116 KGLGITALMMFNAGAQTTVPVDV--LRSLPKLTHFRLNAGRNITLHANMFANTPP----- 168
+G G+TA+ T + +++ ++S+P R I L N A P
Sbjct: 296 RGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG 355
Query: 169 ---LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
L L L KIT LP F GL L+ L + N+I I AF+ L N+++LSL N
Sbjct: 356 LRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDN 415
Query: 226 RIQALPAGLFASTPRLLNLTMMRNSF 251
+IQ+L G F S + L + +N F
Sbjct: 416 KIQSLAKGTFTSLRAIQTLHLAQNPF 441
Score = 50.8 bits (116), Expect = 8e-06
Identities = 36/153 (23%), Positives = 69/153 (45%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T + N T + + L +L +L + + F + L+ L L+ ++
Sbjct: 63 TERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLH 122
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
+LP+ F L +L++ EN I I AFRG ++ L L+KN+I + G F +
Sbjct: 123 MLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRG 182
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L LT+ N+ + +F + ++ ++ +N
Sbjct: 183 LEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 50.0 bits (114), Expect = 1e-05
Identities = 37/116 (31%), Positives = 60/116 (51%), Gaps = 6/116 (5%)
Query: 139 LRSLPK-----LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
LR+LPK +T L+ G TL + L+ ++LS+ KI+ L + +F ++ L
Sbjct: 752 LRALPKGIPKNVTELYLD-GNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQL 810
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
L + N + I AF+GL ++ +LSL+ N I L G+FA L +L + N
Sbjct: 811 TTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGAN 866
Score = 48.8 bits (111), Expect = 3e-05
Identities = 32/129 (24%), Positives = 59/129 (45%), Gaps = 1/129 (0%)
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
+T + L N I+++P G F+ +L + + N + + F+GL + + + N
Sbjct: 311 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 370
Query: 277 TLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
L VF L L+ L L+ + I + P+ F L LSL N+++ L +
Sbjct: 371 DLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRA 430
Query: 336 LTSLTLSYN 344
+ +L L+ N
Sbjct: 431 IQTLHLAQN 439
Score = 47.6 bits (108), Expect = 8e-05
Identities = 69/280 (24%), Positives = 113/280 (40%), Gaps = 20/280 (7%)
Query: 95 AEDVKTVVF-KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAG 153
A D+K + KN I+ + AF+ L ++ N TT+PV +PKL
Sbjct: 156 ATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKL-------- 207
Query: 154 RNITLHANMFANTPPLKYL-ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR 212
R LH+N L +L + + T+ G L LNV E + + +
Sbjct: 208 RTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQG 267
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISN 272
V +L+ + PA S + R + L + + + EI++
Sbjct: 268 EAGRVPTCTLSSG---SCPAMCTCSN----GIVDCRG--KGLTAIPANLPETMTEIRLEL 318
Query: 273 NVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLR 331
N ++ FS LR + L + I E+ P+ F L +L L N++ LPR V
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 378
Query: 332 GQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
G L L L+ N + + P+ F DL+ L + N++Q
Sbjct: 379 GLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQ 418
Score = 47.2 bits (107), Expect = 1e-04
Identities = 33/111 (29%), Positives = 51/111 (45%), Gaps = 3/111 (2%)
Query: 144 KLTHFR-LNAGRNIT--LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
KLTH + +N N + F + L L+ ++ + F GL+ L L +
Sbjct: 563 KLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRN 622
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
N I+ I +F GL NV +LSL N+I + G F + L L ++ N F
Sbjct: 623 NRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPF 673
Score = 45.6 bits (103), Expect = 3e-04
Identities = 25/79 (31%), Positives = 42/79 (53%)
Query: 292 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAP 351
L LD + +P + + L+ + L+ N++ L S +QLT+L LSYNA+ + P
Sbjct: 766 LYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPP 825
Query: 352 ELFADLRALETFVMDGNEL 370
F LR+L + GN++
Sbjct: 826 LAFQGLRSLRLLSLHGNDI 844
Score = 44.8 bits (101), Expect = 5e-04
Identities = 30/127 (23%), Positives = 57/127 (44%), Gaps = 2/127 (1%)
Query: 244 LTMMRNSFRYLDSE-TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL 302
L + N L++ F+ L H+++I +SNN +++ F ++ L L + + +
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 303 PE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALE 361
F LRTL L N++ + G + L+L N + ++P F L++L
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 362 TFVMDGN 368
T + N
Sbjct: 665 TLNLLAN 671
Score = 44.4 bits (100), Expect = 7e-04
Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 5/128 (3%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
TV+ + ++ALP G+ + L + N F + + ++Q + +SNN +
Sbjct: 743 TVVRCSNKHLRALPKGI---PKNVTELYLDGNQFTLVPGQ-LSTFKYLQLVDLSNNKISS 798
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
L + F+N+ L TL L ++++ +P F LR LSL N + L + T L
Sbjct: 799 LSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSL 858
Query: 337 TSLTLSYN 344
+ L + N
Sbjct: 859 SHLAIGAN 866
Score = 41.1 bits (92), Expect = 0.007
Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 1/121 (0%)
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
N I +I GAF + + L+ N+I + F L +L + N L F
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 378
Query: 261 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLAR 319
GL +Q + ++ N ++ F +L L L L + I+ L + F S ++TL LA+
Sbjct: 379 GLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQ 438
Query: 320 N 320
N
Sbjct: 439 N 439
Score = 39.9 bits (89), Expect = 0.015
Identities = 41/155 (26%), Positives = 63/155 (40%), Gaps = 11/155 (7%)
Query: 50 IDCMGGELVC--AEFPEIDTPATTQLPSLSLRECSLPPLSCL-LQKVHAEDVKTVVFKNA 106
+DC G L A PE T +L + S+PP + +K+ D+ N
Sbjct: 293 VDCRGKGLTAIPANLPETMTEIRLELNGIK----SIPPGAFSPYRKLRRIDLSN----NQ 344
Query: 107 INPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANT 166
I + DAF+GL ++ T +P V L L LNA + + + F +
Sbjct: 345 IAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDL 404
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
L L L D KI L F L ++ L++ +N
Sbjct: 405 QNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 439
Score = 36.7 bits (81), Expect = 0.14
Identities = 28/110 (25%), Positives = 50/110 (45%)
Query: 116 KGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELS 175
KG+ ++ G Q T+ L + L L+ + +L + F N L L LS
Sbjct: 757 KGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILS 816
Query: 176 DAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
+ +P AF GL L L++ N+I+ + G F + +++ L++ N
Sbjct: 817 YNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGAN 866
Score = 36.3 bits (80), Expect = 0.19
Identities = 26/107 (24%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
Query: 267 EIKISNNVPLTLKEA--VFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLR 323
E++++NN +++ EA +F L L+ + L + + E+ + F + + L L NQL
Sbjct: 544 ELRLNNN-EISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLE 602
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ + RG L +L L N ++ + + F LR + + N++
Sbjct: 603 SIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQI 649
>AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1534
Score = 77.8 bits (183), Expect = 6e-14
Identities = 46/152 (30%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
LEL+ IT + + F GL L L + EN+I + GAF + + L LN+N++ LP
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
LF + L L + N+ + + + FRG ++ +++ N ++E F L L
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 292 LQLDLSSIRELPEEFISNSP-LRTLSLARNQL 322
L L+ ++I +P ++ P LRT L N L
Sbjct: 186 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 75.4 bits (177), Expect = 3e-13
Identities = 47/157 (29%), Positives = 84/157 (53%), Gaps = 3/157 (1%)
Query: 140 RSLPKLTH-FRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
+++P+ T LN G NIT +H N FA L+ L+L + +I + AF + LE+L
Sbjct: 57 KNIPRNTERLELN-GNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLR 115
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSE 257
+ N++ + F+ ++ L L++N IQA+P F L NL + +N ++
Sbjct: 116 LNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEG 175
Query: 258 TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
FR L ++ + ++NN T+ + F+++P LRT +L
Sbjct: 176 AFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRL 212
Score = 67.7 bits (158), Expect = 7e-11
Identities = 45/134 (33%), Positives = 64/134 (47%), Gaps = 3/134 (2%)
Query: 116 KGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELS 175
K L + LM GA D ++ L +L RLN + L +F N L L+LS
Sbjct: 85 KQLRVLQLMENQIGAVERGAFDDMKELERL---RLNRNQLHMLPELLFQNNQALSRLDLS 141
Query: 176 DAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLF 235
+ I +P AF G L+ L + +N+I+ I GAFR L + VL+LN N I +P F
Sbjct: 142 ENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSF 201
Query: 236 ASTPRLLNLTMMRN 249
P+L + N
Sbjct: 202 NHMPKLRTFRLHSN 215
Score = 67.3 bits (157), Expect = 9e-11
Identities = 40/154 (25%), Positives = 74/154 (48%), Gaps = 4/154 (2%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
T + + +QA+P + +T RL + N+ + F GL ++ +++ N
Sbjct: 43 TTVDCHGTGLQAIPKNIPRNTERL---ELNGNNITRIHKNDFAGLKQLRVLQLMENQIGA 99
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
++ F ++ L L+L+ + + LPE F +N L L L+ N ++ +PR RG T L
Sbjct: 100 VERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDL 159
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+L L N ++ + F LR LE ++ N +
Sbjct: 160 KNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNI 193
Score = 64.1 bits (149), Expect = 8e-10
Identities = 42/156 (26%), Positives = 70/156 (44%), Gaps = 1/156 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L LN N I + FA +L L +M N ++ F + ++ ++++ N
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
L E +F N AL L L ++I+ +P + F + L+ L L +NQ+ + R
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 181
Query: 335 QLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L LTL+ N + + F + L TF + N L
Sbjct: 182 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 63.7 bits (148), Expect = 1e-09
Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 1/134 (0%)
Query: 141 SLPK-LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
+LP+ +T RL ++ F+ L+ ++LS+ +I + DAF GL L L ++
Sbjct: 306 NLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLY 365
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
N+I ++ G F GL+ + +L LN N+I + F L L++ N + L TF
Sbjct: 366 GNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTF 425
Query: 260 RGLDHIQEIKISNN 273
L IQ + ++ N
Sbjct: 426 TSLRAIQTLHLAQN 439
Score = 62.9 bits (146), Expect = 2e-09
Identities = 34/124 (27%), Positives = 68/124 (54%), Gaps = 1/124 (0%)
Query: 172 LELSDAKITVLPDDA-FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
L L++ +I++L F L L+++N+ N+++ I GAF G +V+ L L N+++++
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
+G+F L L + N + +++F GL +++ + + +N T+ F L +L
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 291 TLQL 294
TL L
Sbjct: 665 TLNL 668
Score = 60.5 bits (140), Expect = 1e-08
Identities = 41/143 (28%), Positives = 74/143 (51%), Gaps = 4/143 (2%)
Query: 153 GRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAF 211
G+ +T + AN+ ++ LEL+ K +P AF L ++++ N+IA I AF
Sbjct: 297 GKGLTAIPANLPETMTEIR-LELNGIKS--IPPGAFSPYRKLRRIDLSNNQIAEIAPDAF 353
Query: 212 RGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKIS 271
+GL ++ L L N+I LP G+F L L + N + + F+ L ++ + +
Sbjct: 354 QGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLY 413
Query: 272 NNVPLTLKEAVFSNLPALRTLQL 294
+N +L + F++L A++TL L
Sbjct: 414 DNKIQSLAKGTFTSLRAIQTLHL 436
Score = 57.6 bits (133), Expect = 7e-08
Identities = 42/152 (27%), Positives = 63/152 (41%), Gaps = 1/152 (0%)
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
E+L + N I I F GL + VL L +N+I A+ G F L L + RN
Sbjct: 64 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHM 123
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPL 312
L F+ + + +S N + F L+ LQLD + I + E F + L
Sbjct: 124 LPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGL 183
Query: 313 RTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
L+L N + +P S +L + L N
Sbjct: 184 EVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 55.6 bits (128), Expect = 3e-07
Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 4/143 (2%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNITLHAN-MFANTPPLKYLELSDAKITVLPDDAFLGL 190
T +P + +S +L RLN L A MF LK + LS+ K++ + D AF G
Sbjct: 532 TKIPERIPQSTAEL---RLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGA 588
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS 250
+ +L++ N++ +I +G FRGL + L L NRI + F + L++ N
Sbjct: 589 ASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQ 648
Query: 251 FRYLDSETFRGLDHIQEIKISNN 273
+ F L + + + N
Sbjct: 649 ITTVSPGAFDTLQSLSTLNLLAN 671
Score = 55.2 bits (127), Expect = 4e-07
Identities = 46/146 (31%), Positives = 68/146 (46%), Gaps = 10/146 (6%)
Query: 116 KGLGITALMMFNAGAQTTVPVDV--LRSLPKLTHFRLNAGRNITLHANMFANTPP----- 168
+G G+TA+ T + +++ ++S+P R I L N A P
Sbjct: 296 RGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG 355
Query: 169 ---LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
L L L KIT LP F GL L+ L + N+I I AF+ L N+++LSL N
Sbjct: 356 LRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDN 415
Query: 226 RIQALPAGLFASTPRLLNLTMMRNSF 251
+IQ+L G F S + L + +N F
Sbjct: 416 KIQSLAKGTFTSLRAIQTLHLAQNPF 441
Score = 50.8 bits (116), Expect = 8e-06
Identities = 36/153 (23%), Positives = 69/153 (45%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T + N T + + L +L +L + + F + L+ L L+ ++
Sbjct: 63 TERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLH 122
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
+LP+ F L +L++ EN I I AFRG ++ L L+KN+I + G F +
Sbjct: 123 MLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRG 182
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L LT+ N+ + +F + ++ ++ +N
Sbjct: 183 LEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 215
Score = 50.0 bits (114), Expect = 1e-05
Identities = 37/116 (31%), Positives = 60/116 (51%), Gaps = 6/116 (5%)
Query: 139 LRSLPK-----LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
LR+LPK +T L+ G TL + L+ ++LS+ KI+ L + +F ++ L
Sbjct: 752 LRALPKGIPKNVTELYLD-GNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQL 810
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
L + N + I AF+GL ++ +LSL+ N I L G+FA L +L + N
Sbjct: 811 TTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGAN 866
Score = 48.8 bits (111), Expect = 3e-05
Identities = 32/129 (24%), Positives = 59/129 (45%), Gaps = 1/129 (0%)
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
+T + L N I+++P G F+ +L + + N + + F+GL + + + N
Sbjct: 311 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 370
Query: 277 TLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
L VF L L+ L L+ + I + P+ F L LSL N+++ L +
Sbjct: 371 DLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRA 430
Query: 336 LTSLTLSYN 344
+ +L L+ N
Sbjct: 431 IQTLHLAQN 439
Score = 47.6 bits (108), Expect = 8e-05
Identities = 69/280 (24%), Positives = 113/280 (40%), Gaps = 20/280 (7%)
Query: 95 AEDVKTVVF-KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAG 153
A D+K + KN I+ + AF+ L ++ N TT+PV +PKL
Sbjct: 156 ATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKL-------- 207
Query: 154 RNITLHANMFANTPPLKYL-ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR 212
R LH+N L +L + + T+ G L LNV E + + +
Sbjct: 208 RTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQG 267
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISN 272
V +L+ + PA S + R + L + + + EI++
Sbjct: 268 EAGRVPTCTLSSG---SCPAMCTCSN----GIVDCRG--KGLTAIPANLPETMTEIRLEL 318
Query: 273 NVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLR 331
N ++ FS LR + L + I E+ P+ F L +L L N++ LPR V
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 378
Query: 332 GQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
G L L L+ N + + P+ F DL+ L + N++Q
Sbjct: 379 GLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQ 418
Score = 47.2 bits (107), Expect = 1e-04
Identities = 33/111 (29%), Positives = 51/111 (45%), Gaps = 3/111 (2%)
Query: 144 KLTHFR-LNAGRNIT--LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
KLTH + +N N + F + L L+ ++ + F GL+ L L +
Sbjct: 563 KLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRN 622
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
N I+ I +F GL NV +LSL N+I + G F + L L ++ N F
Sbjct: 623 NRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPF 673
Score = 45.6 bits (103), Expect = 3e-04
Identities = 25/79 (31%), Positives = 42/79 (53%)
Query: 292 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAP 351
L LD + +P + + L+ + L+ N++ L S +QLT+L LSYNA+ + P
Sbjct: 766 LYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPP 825
Query: 352 ELFADLRALETFVMDGNEL 370
F LR+L + GN++
Sbjct: 826 LAFQGLRSLRLLSLHGNDI 844
Score = 44.8 bits (101), Expect = 5e-04
Identities = 30/127 (23%), Positives = 57/127 (44%), Gaps = 2/127 (1%)
Query: 244 LTMMRNSFRYLDSE-TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL 302
L + N L++ F+ L H+++I +SNN +++ F ++ L L + + +
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 303 PE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALE 361
F LRTL L N++ + G + L+L N + ++P F L++L
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 362 TFVMDGN 368
T + N
Sbjct: 665 TLNLLAN 671
Score = 44.4 bits (100), Expect = 7e-04
Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 5/128 (3%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
TV+ + ++ALP G+ + L + N F + + ++Q + +SNN +
Sbjct: 743 TVVRCSNKHLRALPKGI---PKNVTELYLDGNQFTLVPGQ-LSTFKYLQLVDLSNNKISS 798
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
L + F+N+ L TL L ++++ +P F LR LSL N + L + T L
Sbjct: 799 LSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSL 858
Query: 337 TSLTLSYN 344
+ L + N
Sbjct: 859 SHLAIGAN 866
Score = 41.1 bits (92), Expect = 0.007
Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 1/121 (0%)
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
N I +I GAF + + L+ N+I + F L +L + N L F
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 378
Query: 261 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLAR 319
GL +Q + ++ N ++ F +L L L L + I+ L + F S ++TL LA+
Sbjct: 379 GLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQ 438
Query: 320 N 320
N
Sbjct: 439 N 439
Score = 39.9 bits (89), Expect = 0.015
Identities = 41/155 (26%), Positives = 63/155 (40%), Gaps = 11/155 (7%)
Query: 50 IDCMGGELVC--AEFPEIDTPATTQLPSLSLRECSLPPLSCL-LQKVHAEDVKTVVFKNA 106
+DC G L A PE T +L + S+PP + +K+ D+ N
Sbjct: 293 VDCRGKGLTAIPANLPETMTEIRLELNGIK----SIPPGAFSPYRKLRRIDLSN----NQ 344
Query: 107 INPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANT 166
I + DAF+GL ++ T +P V L L LNA + + + F +
Sbjct: 345 IAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDL 404
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
L L L D KI L F L ++ L++ +N
Sbjct: 405 QNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 439
Score = 36.7 bits (81), Expect = 0.14
Identities = 28/110 (25%), Positives = 50/110 (45%)
Query: 116 KGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELS 175
KG+ ++ G Q T+ L + L L+ + +L + F N L L LS
Sbjct: 757 KGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILS 816
Query: 176 DAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
+ +P AF GL L L++ N+I+ + G F + +++ L++ N
Sbjct: 817 YNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGAN 866
Score = 36.3 bits (80), Expect = 0.19
Identities = 26/107 (24%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
Query: 267 EIKISNNVPLTLKEA--VFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLR 323
E++++NN +++ EA +F L L+ + L + + E+ + F + + L L NQL
Sbjct: 544 ELRLNNN-EISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLE 602
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ + RG L +L L N ++ + + F LR + + N++
Sbjct: 603 SIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQI 649
>AF532858-1|AAP21835.1| 420|Homo sapiens Nogo-66 receptor homolog-1
protein.
Length = 420
Score = 77.8 bits (183), Expect = 6e-14
Identities = 66/204 (32%), Positives = 100/204 (49%), Gaps = 4/204 (1%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P + L L + I L F G N+L L ++ N ++ I G FR L + L L NR
Sbjct: 60 PSTQRLFLQNNLIRTLRPGTF-GSNLLT-LWLFSNNLSTIYPGTFRHLQALEELDLGDNR 117
Query: 227 -IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSN 285
+++L F RL +L + R L FRGL +Q + + N L L++ +F++
Sbjct: 118 HLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFAD 177
Query: 286 LPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
L L L L + +R L E F L L L N+L+ + R+ RG ++LT L L N
Sbjct: 178 LANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNN 237
Query: 345 AVAELAPELFADLRALETFVMDGN 368
++A L E ADL +LE ++ N
Sbjct: 238 SLASLPGEALADLPSLEFLRLNAN 261
Score = 71.7 bits (168), Expect = 4e-12
Identities = 49/166 (29%), Positives = 80/166 (48%), Gaps = 2/166 (1%)
Query: 157 TLHANMFANTPPLKYLELSDAK-ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLH 215
T++ F + L+ L+L D + + L D F GL L+ L+++ +++++ FRGL
Sbjct: 96 TIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLV 155
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
++ L L +N + L LFA L +L + N R L FRGL + + + N
Sbjct: 156 SLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRL 215
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARN 320
+ A F L L L L +S+ LP E +++ P L L L N
Sbjct: 216 QGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 63.7 bits (148), Expect = 1e-09
Identities = 53/155 (34%), Positives = 74/155 (47%), Gaps = 7/155 (4%)
Query: 220 LSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLK 279
+S N ++P L ST RL + N R L TF G + + SNN+ T+
Sbjct: 44 VSCQANNFSSVPLSLPPSTQRLF---LQNNLIRTLRPGTF-GSNLLTLWLFSNNLS-TIY 98
Query: 280 EAVFSNLPALRTLQL-DLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLT 337
F +L AL L L D +R L P+ F L++L L R QL LP ++ RG L
Sbjct: 99 PGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQ 158
Query: 338 SLTLSYNAVAELAPELFADLRALETFVMDGNELQV 372
L L N++ L +LFADL L + GN L++
Sbjct: 159 YLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRL 193
Score = 60.1 bits (139), Expect = 1e-08
Identities = 44/173 (25%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Query: 102 VFKNAINPLNADAFKGL-GITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHA 160
+F N ++ + F+ L + L + + ++ D + L +L L + +L
Sbjct: 89 LFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPG 148
Query: 161 NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVL 220
N+F L+YL L + + L DD F L L L + N + +T FRGL ++ L
Sbjct: 149 NIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRL 208
Query: 221 SLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L+ NR+Q + F RL L + NS L E L ++ ++++ N
Sbjct: 209 LLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 54.4 bits (125), Expect = 7e-07
Identities = 48/179 (26%), Positives = 79/179 (44%), Gaps = 4/179 (2%)
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS-FR 252
++L + N I + G F N+ L L N + + G F L L + N R
Sbjct: 63 QRLFLQNNLIRTLRPGTFGS--NLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLR 120
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SP 311
L+ +TF+GL+ +Q + + +L +F L +L+ L L +S+ L ++ ++ +
Sbjct: 121 SLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLAN 180
Query: 312 LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L L L N+LR+L V RG L L L N + + F L L + N L
Sbjct: 181 LSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSL 239
>AF371328-1|AAK51556.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 77.8 bits (183), Expect = 6e-14
Identities = 63/238 (26%), Positives = 106/238 (44%), Gaps = 6/238 (2%)
Query: 139 LRSLPKLTHFR--LNAGRNI--TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLE 194
L+ +PK++ LN RN L AN F P L L L +I + AF GL L
Sbjct: 43 LQKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLI 102
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
L + N+I + AGAF L +T L L+ N++ LP GL + L L + N R L
Sbjct: 103 YLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIREL 162
Query: 255 DSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLR 313
+ F+G ++ + +S N +L+ ++ L +D + + P +S +
Sbjct: 163 RAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVE 222
Query: 314 TLSLARNQLRVLPRSVLRG-QTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L L+ N L+ +P + + L +L L + + + F + L+ ++ N L
Sbjct: 223 ELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRL 280
Score = 71.7 bits (168), Expect = 4e-12
Identities = 64/256 (25%), Positives = 110/256 (42%), Gaps = 5/256 (1%)
Query: 90 LQKVHAEDVKTVVF---KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLT 146
LQK+ KT + +N L A++F+ + + V R L +L
Sbjct: 43 LQKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLI 102
Query: 147 HFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANI 206
+ L+ L A F + L YL L K+T LP L L L + N+I +
Sbjct: 103 YLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIREL 162
Query: 207 TAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQ 266
AGAF+G ++ L L++N + +L G L + RN S L ++
Sbjct: 163 RAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVE 222
Query: 267 EIKISNNVPLTLKEAVFSNLPA-LRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRV 324
E+K+S+N ++ + F + L TL LD +++ + + F+ + L+ + L N+L
Sbjct: 223 ELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQ 282
Query: 325 LPRSVLRGQTQLTSLT 340
LP + + +LT
Sbjct: 283 LPSNFPFDSLETLALT 298
Score = 58.8 bits (136), Expect = 3e-08
Identities = 57/265 (21%), Positives = 108/265 (40%), Gaps = 7/265 (2%)
Query: 11 SVSACPEQCWCTDGEELNYQCSRPSTNLIVGARPR-DYVNIDCMGGELVCAEFPEIDTPA 69
+++ACP+ C C + + C + I + +N+ ++ A A
Sbjct: 19 ALAACPQNCHC-HSDLQHVICDKVGLQKIPKVSEKTKLLNLQRNNFPVLAAN----SFRA 73
Query: 70 TTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAG 129
L SL L+ C + ++ + + + + N I L A AF L + +
Sbjct: 74 MPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHN 133
Query: 130 AQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLG 189
T +P +L L L +LN + L A F L++L LS+ ++ L A
Sbjct: 134 KVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDD 193
Query: 190 LNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
+ L + +V N++++ + A L V L L+ N ++++P F S R L + N
Sbjct: 194 VENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDN 253
Query: 250 -SFRYLDSETFRGLDHIQEIKISNN 273
+ F G+ ++ + + NN
Sbjct: 254 TNLEKFSDGAFLGVTTLKHVHLENN 278
Score = 40.3 bits (90), Expect = 0.012
Identities = 32/101 (31%), Positives = 47/101 (46%), Gaps = 2/101 (1%)
Query: 272 NNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVL 330
NN P+ + F +P L +L L IRE+ F L L L+ N +RVL
Sbjct: 61 NNFPVLAANS-FRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAF 119
Query: 331 RGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
T+LT L L +N V EL L + L L ++ N+++
Sbjct: 120 DDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIR 160
>AB208943-1|BAD92180.1| 627|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 7 variant
protein.
Length = 627
Score = 77.8 bits (183), Expect = 6e-14
Identities = 55/173 (31%), Positives = 86/173 (49%), Gaps = 2/173 (1%)
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
N+I +I+ AFRGL+++T L L+ NRI L G+F RL L + N + TF
Sbjct: 30 NKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFY 89
Query: 261 GLDHIQEIKISNNVPLTLKE-AVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLA 318
GL+ + + + NNV L + + ++P L L L+ + I L FIS S L L +
Sbjct: 90 GLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMR 149
Query: 319 RNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
+N++ L + +L L L N + L P +F DL+ L + N +Q
Sbjct: 150 KNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQ 202
Score = 69.3 bits (162), Expect = 2e-11
Identities = 52/199 (26%), Positives = 86/199 (43%), Gaps = 2/199 (1%)
Query: 174 LSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAG 233
L + KIT + AF GLN L +L + N I + G F LH + L + N + +
Sbjct: 27 LQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPP 86
Query: 234 LFASTPRLLNLTMMRNSF-RYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTL 292
F L+ L +M N R D + + + + + N L+ F + L L
Sbjct: 87 TFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVL 146
Query: 293 QLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAP 351
+ + I L E F L L L N++ LP + + +L+ L LSYN + ++
Sbjct: 147 VMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQA 206
Query: 352 ELFADLRALETFVMDGNEL 370
F L L++ ++G E+
Sbjct: 207 NQFDYLVKLKSLSLEGIEI 225
Score = 53.6 bits (123), Expect = 1e-06
Identities = 52/213 (24%), Positives = 84/213 (39%), Gaps = 3/213 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I ++ AF+GL + + T + V L +L + + F
Sbjct: 30 NKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFY 89
Query: 165 NTPPLKYLELSDAKITVLPDDAFLG-LNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
L L L + +T LPD + L L++ N I N+ F N+TVL +
Sbjct: 90 GLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMR 149
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
KN+I L FA +L L + N L F+ L + ++ +S N ++ F
Sbjct: 150 KNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQF 209
Query: 284 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLS 316
L L++L L+ I + + PL LS
Sbjct: 210 DYLVKLKSLSLEGIEISNIQQRMF--RPLMNLS 240
>AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein.
Length = 1618
Score = 77.4 bits (182), Expect = 8e-14
Identities = 46/152 (30%), Positives = 76/152 (50%), Gaps = 1/152 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
LEL+ IT + + F GL L L + EN+I + GAF + + L LN+N++ LP
Sbjct: 150 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQLHMLP 209
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
LF + L L + N+ + + + FRG ++ +++ N ++E F L L
Sbjct: 210 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 269
Query: 292 LQLDLSSIRELPEEFISNSP-LRTLSLARNQL 322
L L+ ++I +P ++ P LRT L N L
Sbjct: 270 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 301
Score = 77.0 bits (181), Expect = 1e-13
Identities = 48/157 (30%), Positives = 85/157 (54%), Gaps = 3/157 (1%)
Query: 140 RSLPKLTH-FRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
+++P+ T LN G NIT +H N FA L+ L+L + +I V+ AF + LE+L
Sbjct: 141 KNIPRNTERLELN-GNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLR 199
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSE 257
+ N++ + F+ ++ L L++N IQA+P F L NL + +N ++
Sbjct: 200 LNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEG 259
Query: 258 TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
FR L ++ + ++NN T+ + F+++P LRT +L
Sbjct: 260 AFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRL 296
Score = 67.7 bits (158), Expect = 7e-11
Identities = 43/145 (29%), Positives = 65/145 (44%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I ++ + F GL ++ V + +L RLN + L +F
Sbjct: 155 NNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQLHMLPELLFQ 214
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N L L+LS+ I +P AF G L+ L + +N+I+ I GAFR L + VL+LN
Sbjct: 215 NNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNN 274
Query: 225 NRIQALPAGLFASTPRLLNLTMMRN 249
N I +P F P+L + N
Sbjct: 275 NNITTIPVSSFNHMPKLRTFRLHSN 299
Score = 67.3 bits (157), Expect = 9e-11
Identities = 40/154 (25%), Positives = 74/154 (48%), Gaps = 4/154 (2%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
T + + +QA+P + +T RL + N+ + F GL ++ +++ N
Sbjct: 127 TTVDCHGTGLQAIPKNIPRNTERL---ELNGNNITRIHKNDFAGLKQLRVLQLMENQIGV 183
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
++ F ++ L L+L+ + + LPE F +N L L L+ N ++ +PR RG T L
Sbjct: 184 VERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDL 243
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+L L N ++ + F LR LE ++ N +
Sbjct: 244 KNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNI 277
Score = 64.5 bits (150), Expect = 6e-10
Identities = 42/156 (26%), Positives = 70/156 (44%), Gaps = 1/156 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L LN N I + FA +L L +M N ++ F + ++ ++++ N
Sbjct: 146 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQL 205
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
L E +F N AL L L ++I+ +P + F + L+ L L +NQ+ + R
Sbjct: 206 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 265
Query: 335 QLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L LTL+ N + + F + L TF + N L
Sbjct: 266 GLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 301
Score = 63.7 bits (148), Expect = 1e-09
Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 1/134 (0%)
Query: 141 SLPK-LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
+LP+ +T RL ++ F+ L+ ++LS+ +I + DAF GL L L ++
Sbjct: 390 NLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLY 449
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
N+I ++ G F GL+ + +L LN N+I + F L L++ N + L TF
Sbjct: 450 GNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTF 509
Query: 260 RGLDHIQEIKISNN 273
L IQ + ++ N
Sbjct: 510 TSLRAIQTLHLAQN 523
Score = 62.9 bits (146), Expect = 2e-09
Identities = 34/124 (27%), Positives = 68/124 (54%), Gaps = 1/124 (0%)
Query: 172 LELSDAKITVLPDDA-FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
L L++ +I++L F L L+++N+ N+++ I GAF G +V+ L L N+++++
Sbjct: 629 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 688
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
+G+F L L + N + +++F GL +++ + + +N T+ F L +L
Sbjct: 689 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 748
Query: 291 TLQL 294
TL L
Sbjct: 749 TLNL 752
Score = 60.5 bits (140), Expect = 1e-08
Identities = 41/143 (28%), Positives = 74/143 (51%), Gaps = 4/143 (2%)
Query: 153 GRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAF 211
G+ +T + AN+ ++ LEL+ K +P AF L ++++ N+IA I AF
Sbjct: 381 GKGLTAIPANLPETMTEIR-LELNGIKS--IPPGAFSPYRKLRRIDLSNNQIAEIAPDAF 437
Query: 212 RGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKIS 271
+GL ++ L L N+I LP G+F L L + N + + F+ L ++ + +
Sbjct: 438 QGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLY 497
Query: 272 NNVPLTLKEAVFSNLPALRTLQL 294
+N +L + F++L A++TL L
Sbjct: 498 DNKIQSLAKGTFTSLRAIQTLHL 520
Score = 56.0 bits (129), Expect = 2e-07
Identities = 41/152 (26%), Positives = 62/152 (40%), Gaps = 1/152 (0%)
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
E+L + N I I F GL + VL L +N+I + G F L L + RN
Sbjct: 148 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQLHM 207
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPL 312
L F+ + + +S N + F L+ LQLD + I + E F + L
Sbjct: 208 LPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGL 267
Query: 313 RTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
L+L N + +P S +L + L N
Sbjct: 268 EVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 299
Score = 55.6 bits (128), Expect = 3e-07
Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 4/143 (2%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNITLHAN-MFANTPPLKYLELSDAKITVLPDDAFLGL 190
T +P + +S +L RLN L A MF LK + LS+ K++ + D AF G
Sbjct: 616 TKIPERIPQSTAEL---RLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGA 672
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS 250
+ +L++ N++ +I +G FRGL + L L NRI + F + L++ N
Sbjct: 673 ASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQ 732
Query: 251 FRYLDSETFRGLDHIQEIKISNN 273
+ F L + + + N
Sbjct: 733 ITTVSPGAFDTLQSLSTLNLLAN 755
Score = 55.2 bits (127), Expect = 4e-07
Identities = 46/146 (31%), Positives = 68/146 (46%), Gaps = 10/146 (6%)
Query: 116 KGLGITALMMFNAGAQTTVPVDV--LRSLPKLTHFRLNAGRNITLHANMFANTPP----- 168
+G G+TA+ T + +++ ++S+P R I L N A P
Sbjct: 380 RGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG 439
Query: 169 ---LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
L L L KIT LP F GL L+ L + N+I I AF+ L N+++LSL N
Sbjct: 440 LRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDN 499
Query: 226 RIQALPAGLFASTPRLLNLTMMRNSF 251
+IQ+L G F S + L + +N F
Sbjct: 500 KIQSLAKGTFTSLRAIQTLHLAQNPF 525
Score = 50.8 bits (116), Expect = 8e-06
Identities = 36/153 (23%), Positives = 69/153 (45%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T + N T + + L +L +L + + F + L+ L L+ ++
Sbjct: 147 TERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQLH 206
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
+LP+ F L +L++ EN I I AFRG ++ L L+KN+I + G F +
Sbjct: 207 MLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRG 266
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L LT+ N+ + +F + ++ ++ +N
Sbjct: 267 LEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSN 299
Score = 50.0 bits (114), Expect = 1e-05
Identities = 37/116 (31%), Positives = 60/116 (51%), Gaps = 6/116 (5%)
Query: 139 LRSLPK-----LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
LR+LPK +T L+ G TL + L+ ++LS+ KI+ L + +F ++ L
Sbjct: 836 LRALPKGIPKNVTELYLD-GNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQL 894
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
L + N + I AF+GL ++ +LSL+ N I L G+FA L +L + N
Sbjct: 895 TTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGAN 950
Score = 48.8 bits (111), Expect = 3e-05
Identities = 32/129 (24%), Positives = 59/129 (45%), Gaps = 1/129 (0%)
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
+T + L N I+++P G F+ +L + + N + + F+GL + + + N
Sbjct: 395 MTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKIT 454
Query: 277 TLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
L VF L L+ L L+ + I + P+ F L LSL N+++ L +
Sbjct: 455 DLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRA 514
Query: 336 LTSLTLSYN 344
+ +L L+ N
Sbjct: 515 IQTLHLAQN 523
Score = 47.6 bits (108), Expect = 8e-05
Identities = 69/280 (24%), Positives = 113/280 (40%), Gaps = 20/280 (7%)
Query: 95 AEDVKTVVF-KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAG 153
A D+K + KN I+ + AF+ L ++ N TT+PV +PKL
Sbjct: 240 ATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKL-------- 291
Query: 154 RNITLHANMFANTPPLKYL-ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR 212
R LH+N L +L + + T+ G L LNV E + + +
Sbjct: 292 RTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQG 351
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISN 272
V +L+ + PA S + R + L + + + EI++
Sbjct: 352 EAGRVPTCTLSSG---SCPAMCTCSN----GIVDCRG--KGLTAIPANLPETMTEIRLEL 402
Query: 273 NVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLR 331
N ++ FS LR + L + I E+ P+ F L +L L N++ LPR V
Sbjct: 403 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 462
Query: 332 GQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
G L L L+ N + + P+ F DL+ L + N++Q
Sbjct: 463 GLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQ 502
Score = 47.2 bits (107), Expect = 1e-04
Identities = 33/111 (29%), Positives = 51/111 (45%), Gaps = 3/111 (2%)
Query: 144 KLTHFR-LNAGRNIT--LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
KLTH + +N N + F + L L+ ++ + F GL+ L L +
Sbjct: 647 KLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRN 706
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
N I+ I +F GL NV +LSL N+I + G F + L L ++ N F
Sbjct: 707 NRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPF 757
Score = 45.6 bits (103), Expect = 3e-04
Identities = 25/79 (31%), Positives = 42/79 (53%)
Query: 292 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAP 351
L LD + +P + + L+ + L+ N++ L S +QLT+L LSYNA+ + P
Sbjct: 850 LYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPP 909
Query: 352 ELFADLRALETFVMDGNEL 370
F LR+L + GN++
Sbjct: 910 LAFQGLRSLRLLSLHGNDI 928
Score = 44.8 bits (101), Expect = 5e-04
Identities = 30/127 (23%), Positives = 57/127 (44%), Gaps = 2/127 (1%)
Query: 244 LTMMRNSFRYLDSE-TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL 302
L + N L++ F+ L H+++I +SNN +++ F ++ L L + + +
Sbjct: 629 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 688
Query: 303 PE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALE 361
F LRTL L N++ + G + L+L N + ++P F L++L
Sbjct: 689 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 748
Query: 362 TFVMDGN 368
T + N
Sbjct: 749 TLNLLAN 755
Score = 44.4 bits (100), Expect = 7e-04
Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 5/128 (3%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
TV+ + ++ALP G+ + L + N F + + ++Q + +SNN +
Sbjct: 827 TVVRCSNKHLRALPKGI---PKNVTELYLDGNQFTLVPGQ-LSTFKYLQLVDLSNNKISS 882
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
L + F+N+ L TL L ++++ +P F LR LSL N + L + T L
Sbjct: 883 LSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSL 942
Query: 337 TSLTLSYN 344
+ L + N
Sbjct: 943 SHLAIGAN 950
Score = 41.1 bits (92), Expect = 0.007
Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 1/121 (0%)
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
N I +I GAF + + L+ N+I + F L +L + N L F
Sbjct: 403 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 462
Query: 261 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLAR 319
GL +Q + ++ N ++ F +L L L L + I+ L + F S ++TL LA+
Sbjct: 463 GLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQ 522
Query: 320 N 320
N
Sbjct: 523 N 523
Score = 39.9 bits (89), Expect = 0.015
Identities = 41/155 (26%), Positives = 63/155 (40%), Gaps = 11/155 (7%)
Query: 50 IDCMGGELVC--AEFPEIDTPATTQLPSLSLRECSLPPLSCL-LQKVHAEDVKTVVFKNA 106
+DC G L A PE T +L + S+PP + +K+ D+ N
Sbjct: 377 VDCRGKGLTAIPANLPETMTEIRLELNGIK----SIPPGAFSPYRKLRRIDLSN----NQ 428
Query: 107 INPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANT 166
I + DAF+GL ++ T +P V L L LNA + + + F +
Sbjct: 429 IAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDL 488
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
L L L D KI L F L ++ L++ +N
Sbjct: 489 QNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 523
Score = 36.7 bits (81), Expect = 0.14
Identities = 28/110 (25%), Positives = 50/110 (45%)
Query: 116 KGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELS 175
KG+ ++ G Q T+ L + L L+ + +L + F N L L LS
Sbjct: 841 KGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILS 900
Query: 176 DAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
+ +P AF GL L L++ N+I+ + G F + +++ L++ N
Sbjct: 901 YNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGAN 950
Score = 36.3 bits (80), Expect = 0.19
Identities = 26/107 (24%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
Query: 267 EIKISNNVPLTLKEA--VFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLR 323
E++++NN +++ EA +F L L+ + L + + E+ + F + + L L NQL
Sbjct: 628 ELRLNNN-EISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLE 686
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ + RG L +L L N ++ + + F LR + + N++
Sbjct: 687 SIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQI 733
>BC126410-1|AAI26411.1| 516|Homo sapiens leucine rich repeat
transmembrane neuronal 2 protein.
Length = 516
Score = 77.0 bits (181), Expect = 1e-13
Identities = 58/201 (28%), Positives = 91/201 (45%), Gaps = 1/201 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L IT L D F + L L++ N+I+ + AF+GL+ + L L+ N+I LP
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
F L NL + N L E F GL +Q + + +N T+ +F + +L
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 292 LQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L L + +R L F LR L L NQL + + + L +L L +N ++ L
Sbjct: 186 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 245
Query: 351 PELFADLRALETFVMDGNELQ 371
+ LE + GNE++
Sbjct: 246 CGMEWTWGTLEKLDLTGNEIK 266
Score = 72.5 bits (170), Expect = 2e-12
Identities = 58/214 (27%), Positives = 101/214 (47%), Gaps = 1/214 (0%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L + FA+ L +L L +I+ + +DAF GL L++L + N+I + F L N+
Sbjct: 76 LERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINL 135
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
L L+ N++ +L LF +L L + NS R + F ++ + +S N +
Sbjct: 136 QNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRS 195
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
L F+ L LR L L+ + + ++ F+ S L TL L N++ L + L
Sbjct: 196 LARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTL 255
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L L+ N + + +F + L+ +MD N+L
Sbjct: 256 EKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKL 289
Score = 63.3 bits (147), Expect = 1e-09
Identities = 57/241 (23%), Positives = 97/241 (40%), Gaps = 1/241 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I L D F + + +TV D + L KL L++ + L F
Sbjct: 71 NHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFT 130
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L+LS +++ L + F GL L+ L++ N + I F ++ L L+
Sbjct: 131 QLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLST 190
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NR+++L FA +L L + N ++ F L + + + N L +
Sbjct: 191 NRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEW 250
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
L L L + I+ + P L+ L + N+L L +L LT++ LS
Sbjct: 251 TWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSG 310
Query: 344 N 344
N
Sbjct: 311 N 311
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/170 (27%), Positives = 76/170 (44%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ L+ + F GL + + + T+PV + L L+ R +L N FA
Sbjct: 143 NQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFA 202
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L L ++T + FL L+ L L + N+I+N+T G + L L
Sbjct: 203 GLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTG 262
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV 274
N I+A+ +F + P L L M N LDS+ L + + +S N+
Sbjct: 263 NEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGNL 312
Score = 52.4 bits (120), Expect = 3e-06
Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 1/131 (0%)
Query: 242 LNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRE 301
L L++ N L+ + F + + + +N T+KE F L L+ L L + I
Sbjct: 64 LGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFY 123
Query: 302 LPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 360
LP F L+ L L+ NQL L + G +L +L L N++ + LF D R+L
Sbjct: 124 LPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSL 183
Query: 361 ETFVMDGNELQ 371
E + N L+
Sbjct: 184 EFLDLSTNRLR 194
>BC126408-1|AAI26409.1| 516|Homo sapiens leucine rich repeat
transmembrane neuronal 2 protein.
Length = 516
Score = 77.0 bits (181), Expect = 1e-13
Identities = 58/201 (28%), Positives = 91/201 (45%), Gaps = 1/201 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L IT L D F + L L++ N+I+ + AF+GL+ + L L+ N+I LP
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
F L NL + N L E F GL +Q + + +N T+ +F + +L
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 292 LQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L L + +R L F LR L L NQL + + + L +L L +N ++ L
Sbjct: 186 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 245
Query: 351 PELFADLRALETFVMDGNELQ 371
+ LE + GNE++
Sbjct: 246 CGMEWTWGTLEKLDLTGNEIK 266
Score = 72.5 bits (170), Expect = 2e-12
Identities = 58/214 (27%), Positives = 101/214 (47%), Gaps = 1/214 (0%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L + FA+ L +L L +I+ + +DAF GL L++L + N+I + F L N+
Sbjct: 76 LERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINL 135
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
L L+ N++ +L LF +L L + NS R + F ++ + +S N +
Sbjct: 136 QNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRS 195
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
L F+ L LR L L+ + + ++ F+ S L TL L N++ L + L
Sbjct: 196 LARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTL 255
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L L+ N + + +F + L+ +MD N+L
Sbjct: 256 EKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKL 289
Score = 63.3 bits (147), Expect = 1e-09
Identities = 57/241 (23%), Positives = 97/241 (40%), Gaps = 1/241 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I L D F + + +TV D + L KL L++ + L F
Sbjct: 71 NHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFT 130
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L+LS +++ L + F GL L+ L++ N + I F ++ L L+
Sbjct: 131 QLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLST 190
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NR+++L FA +L L + N ++ F L + + + N L +
Sbjct: 191 NRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEW 250
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
L L L + I+ + P L+ L + N+L L +L LT++ LS
Sbjct: 251 TWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSG 310
Query: 344 N 344
N
Sbjct: 311 N 311
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/170 (27%), Positives = 76/170 (44%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ L+ + F GL + + + T+PV + L L+ R +L N FA
Sbjct: 143 NQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFA 202
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L L ++T + FL L+ L L + N+I+N+T G + L L
Sbjct: 203 GLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTG 262
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV 274
N I+A+ +F + P L L M N LDS+ L + + +S N+
Sbjct: 263 NEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGNL 312
Score = 52.4 bits (120), Expect = 3e-06
Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 1/131 (0%)
Query: 242 LNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRE 301
L L++ N L+ + F + + + +N T+KE F L L+ L L + I
Sbjct: 64 LGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFY 123
Query: 302 LPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 360
LP F L+ L L+ NQL L + G +L +L L N++ + LF D R+L
Sbjct: 124 LPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSL 183
Query: 361 ETFVMDGNELQ 371
E + N L+
Sbjct: 184 EFLDLSTNRLR 194
>BC068558-1|AAH68558.1| 614|Homo sapiens LINGO1 protein protein.
Length = 614
Score = 77.0 bits (181), Expect = 1e-13
Identities = 72/281 (25%), Positives = 122/281 (43%), Gaps = 9/281 (3%)
Query: 94 HAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAG 153
H E+++ + +N ++ + AF L + + +P+ V L LT ++
Sbjct: 90 HLEELE--LNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISEN 147
Query: 154 RNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRG 213
+ + L MF + L+ LE+ D + + AF GLN LEQL + + + +I A
Sbjct: 148 KIVILLDYMFQDLYNLRSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSH 207
Query: 214 LHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET---FRGLDHIQEIKI 270
LH + VL L I A+ F RL L + + + YLD+ T GL ++ + I
Sbjct: 208 LHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI--SHWPYLDTMTPNCLYGL-NLTSLSI 264
Query: 271 SNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSV 329
++ + +L LR L L + I + + L+ + L QL V+
Sbjct: 265 THCNLTAVPYLAVRHLVYLRFLNLSYNRISTIEGSMLHELLRLQEIQLVGGQLAVVEPYA 324
Query: 330 LRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
RG L L +S N + L +F + LET ++D N L
Sbjct: 325 FRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 365
Score = 73.7 bits (173), Expect = 1e-12
Identities = 39/140 (27%), Positives = 70/140 (50%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+ L+L +I L D F LE+L + EN ++ + GAF L N+ L L NR++
Sbjct: 68 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 127
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
+P G+F L L + N L F+ L +++ +++ +N + + FS L +L
Sbjct: 128 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLRSLEVGDNDLVYISHRAFSGLNSL 187
Query: 290 RTLQLDLSSIRELPEEFISN 309
L L+ ++ +P E +S+
Sbjct: 188 EQLTLEKCNLTSIPTEALSH 207
Score = 70.1 bits (164), Expect = 1e-11
Identities = 71/264 (26%), Positives = 120/264 (45%), Gaps = 28/264 (10%)
Query: 136 VDVLRSLPKLTHFRLNAGRNI--TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
V V +P T L+ G+N TL+ + FA+ P L+ LEL++ ++ + AF L L
Sbjct: 57 VAVPEGIPTETRL-LDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNL 115
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
L + N + I G F GL N+T L +++N+I L +F L +L + N Y
Sbjct: 116 RTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLRSLEVGDNDLVY 175
Query: 254 LDSETFRGLDHIQEIKISN-NVPLTLKEAV--FSNLPALRTLQLDLSSIRE--------L 302
+ F GL+ ++++ + N+ EA+ L LR L++++IR+ L
Sbjct: 176 ISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRL 235
Query: 303 PEEFISNSP--------------LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
IS+ P L +LS+ L +P +R L L LSYN ++
Sbjct: 236 KVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNRIST 295
Query: 349 LAPELFADLRALETFVMDGNELQV 372
+ + +L L+ + G +L V
Sbjct: 296 IEGSMLHELLRLQEIQLVGGQLAV 319
>AY358284-1|AAQ88651.1| 620|Homo sapiens QVSK201 protein.
Length = 620
Score = 77.0 bits (181), Expect = 1e-13
Identities = 73/281 (25%), Positives = 122/281 (43%), Gaps = 9/281 (3%)
Query: 94 HAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAG 153
H E+++ + +N ++ + AF L + + +P+ V L LT ++
Sbjct: 96 HLEELE--LNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKQDISEN 153
Query: 154 RNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRG 213
+ + L MF + LK LE+ D + + AF GLN LEQL + + + +I A
Sbjct: 154 KIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSH 213
Query: 214 LHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET---FRGLDHIQEIKI 270
LH + VL L I A+ F RL L + + + YLD+ T GL ++ + I
Sbjct: 214 LHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI--SHWPYLDTMTPNCLYGL-NLTSLSI 270
Query: 271 SNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSV 329
++ + +L LR L L + I + + L+ + L QL V+
Sbjct: 271 THCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYA 330
Query: 330 LRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
RG L L +S N + L +F + LET ++D N L
Sbjct: 331 FRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 371
Score = 71.3 bits (167), Expect = 5e-12
Identities = 38/140 (27%), Positives = 69/140 (49%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+ L+L +I L D F LE+L + EN ++ + GAF L N+ L L NR++
Sbjct: 74 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKL 133
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
+P G+F L + N L F+ L +++ +++ +N + + FS L +L
Sbjct: 134 IPLGVFTGLSNLTKQDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSL 193
Query: 290 RTLQLDLSSIRELPEEFISN 309
L L+ ++ +P E +S+
Sbjct: 194 EQLTLEKCNLTSIPTEALSH 213
Score = 67.7 bits (158), Expect = 7e-11
Identities = 70/264 (26%), Positives = 119/264 (45%), Gaps = 28/264 (10%)
Query: 136 VDVLRSLPKLTHFRLNAGRNI--TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
V V +P T L+ G+N TL+ + FA+ P L+ LEL++ ++ + AF L L
Sbjct: 63 VAVPEGIPTETRL-LDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNL 121
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
L + N + I G F GL N+T +++N+I L +F L +L + N Y
Sbjct: 122 RTLGLRSNRLKLIPLGVFTGLSNLTKQDISENKIVILLDYMFQDLYNLKSLEVGDNDLVY 181
Query: 254 LDSETFRGLDHIQEIKISN-NVPLTLKEAV--FSNLPALRTLQLDLSSIRE--------L 302
+ F GL+ ++++ + N+ EA+ L LR L++++IR+ L
Sbjct: 182 ISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRL 241
Query: 303 PEEFISNSP--------------LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
IS+ P L +LS+ L +P +R L L LSYN ++
Sbjct: 242 KVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPIST 301
Query: 349 LAPELFADLRALETFVMDGNELQV 372
+ + +L L+ + G +L V
Sbjct: 302 IEGSMLHELLRLQEIQLVGGQLAV 325
>AY182026-1|AAO67547.1| 516|Homo sapiens leucine-rich repeat
transmembrane neuronal 2 protein protein.
Length = 516
Score = 77.0 bits (181), Expect = 1e-13
Identities = 58/201 (28%), Positives = 91/201 (45%), Gaps = 1/201 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L IT L D F + L L++ N+I+ + AF+GL+ + L L+ N+I LP
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
F L NL + N L E F GL +Q + + +N T+ +F + +L
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 292 LQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L L + +R L F LR L L NQL + + + L +L L +N ++ L
Sbjct: 186 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 245
Query: 351 PELFADLRALETFVMDGNELQ 371
+ LE + GNE++
Sbjct: 246 CGMEWTWGTLEKLDLTGNEIK 266
Score = 72.5 bits (170), Expect = 2e-12
Identities = 58/214 (27%), Positives = 101/214 (47%), Gaps = 1/214 (0%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L + FA+ L +L L +I+ + +DAF GL L++L + N+I + F L N+
Sbjct: 76 LERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINL 135
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
L L+ N++ +L LF +L L + NS R + F ++ + +S N +
Sbjct: 136 QNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRS 195
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
L F+ L LR L L+ + + ++ F+ S L TL L N++ L + L
Sbjct: 196 LARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTL 255
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L L+ N + + +F + L+ +MD N+L
Sbjct: 256 EKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKL 289
Score = 63.3 bits (147), Expect = 1e-09
Identities = 57/241 (23%), Positives = 97/241 (40%), Gaps = 1/241 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I L D F + + +TV D + L KL L++ + L F
Sbjct: 71 NHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFT 130
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L+LS +++ L + F GL L+ L++ N + I F ++ L L+
Sbjct: 131 QLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLST 190
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NR+++L FA +L L + N ++ F L + + + N L +
Sbjct: 191 NRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEW 250
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
L L L + I+ + P L+ L + N+L L +L LT++ LS
Sbjct: 251 TWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSG 310
Query: 344 N 344
N
Sbjct: 311 N 311
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/170 (27%), Positives = 76/170 (44%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ L+ + F GL + + + T+PV + L L+ R +L N FA
Sbjct: 143 NQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFA 202
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L L ++T + FL L+ L L + N+I+N+T G + L L
Sbjct: 203 GLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTG 262
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV 274
N I+A+ +F + P L L M N LDS+ L + + +S N+
Sbjct: 263 NEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGNL 312
Score = 52.4 bits (120), Expect = 3e-06
Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 1/131 (0%)
Query: 242 LNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRE 301
L L++ N L+ + F + + + +N T+KE F L L+ L L + I
Sbjct: 64 LGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFY 123
Query: 302 LPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 360
LP F L+ L L+ NQL L + G +L +L L N++ + LF D R+L
Sbjct: 124 LPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSL 183
Query: 361 ETFVMDGNELQ 371
E + N L+
Sbjct: 184 EFLDLSTNRLR 194
>AB007876-1|BAA24846.2| 529|Homo sapiens KIAA0416 protein.
Length = 529
Score = 77.0 bits (181), Expect = 1e-13
Identities = 58/201 (28%), Positives = 91/201 (45%), Gaps = 1/201 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L IT L D F + L L++ N+I+ + AF+GL+ + L L+ N+I LP
Sbjct: 79 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 138
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
F L NL + N L E F GL +Q + + +N T+ +F + +L
Sbjct: 139 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 198
Query: 292 LQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
L L + +R L F LR L L NQL + + + L +L L +N ++ L
Sbjct: 199 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 258
Query: 351 PELFADLRALETFVMDGNELQ 371
+ LE + GNE++
Sbjct: 259 CGMEWTWGTLEKLDLTGNEIK 279
Score = 72.5 bits (170), Expect = 2e-12
Identities = 58/214 (27%), Positives = 101/214 (47%), Gaps = 1/214 (0%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L + FA+ L +L L +I+ + +DAF GL L++L + N+I + F L N+
Sbjct: 89 LERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINL 148
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
L L+ N++ +L LF +L L + NS R + F ++ + +S N +
Sbjct: 149 QNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRS 208
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
L F+ L LR L L+ + + ++ F+ S L TL L N++ L + L
Sbjct: 209 LARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTL 268
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L L+ N + + +F + L+ +MD N+L
Sbjct: 269 EKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKL 302
Score = 63.3 bits (147), Expect = 1e-09
Identities = 57/241 (23%), Positives = 97/241 (40%), Gaps = 1/241 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I L D F + + +TV D + L KL L++ + L F
Sbjct: 84 NHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFT 143
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L+LS +++ L + F GL L+ L++ N + I F ++ L L+
Sbjct: 144 QLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLST 203
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NR+++L FA +L L + N ++ F L + + + N L +
Sbjct: 204 NRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEW 263
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
L L L + I+ + P L+ L + N+L L +L LT++ LS
Sbjct: 264 TWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSG 323
Query: 344 N 344
N
Sbjct: 324 N 324
Score = 63.3 bits (147), Expect = 1e-09
Identities = 46/170 (27%), Positives = 76/170 (44%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ L+ + F GL + + + T+PV + L L+ R +L N FA
Sbjct: 156 NQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFA 215
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L L ++T + FL L+ L L + N+I+N+T G + L L
Sbjct: 216 GLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTG 275
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV 274
N I+A+ +F + P L L M N LDS+ L + + +S N+
Sbjct: 276 NEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGNL 325
Score = 52.4 bits (120), Expect = 3e-06
Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 1/131 (0%)
Query: 242 LNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRE 301
L L++ N L+ + F + + + +N T+KE F L L+ L L + I
Sbjct: 77 LGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFY 136
Query: 302 LPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 360
LP F L+ L L+ NQL L + G +L +L L N++ + LF D R+L
Sbjct: 137 LPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSL 196
Query: 361 ETFVMDGNELQ 371
E + N L+
Sbjct: 197 EFLDLSTNRLR 207
>BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2
(Drosophila) protein.
Length = 1529
Score = 76.6 bits (180), Expect = 1e-13
Identities = 48/152 (31%), Positives = 75/152 (49%), Gaps = 1/152 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L+L+ IT + F GL L L + EN+I+ I GAF+ L + L LN+N +Q P
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
LF T +L L + N + + + FRG I+ +++ N +++ F L L
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 292 LQLDLSSIRELPEEFISNSP-LRTLSLARNQL 322
L L+ ++I L ++ P LRT L N L
Sbjct: 180 LTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 72.1 bits (169), Expect = 3e-12
Identities = 50/164 (30%), Positives = 84/164 (51%), Gaps = 3/164 (1%)
Query: 138 VLRSLPKLTHFRLNA-GRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQ 195
V R++P+ T RL+ G NIT + FA L+ L+L + KI+ + AF L LE+
Sbjct: 49 VPRNIPRNTE-RLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELER 107
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L + N + F G + L L++N+IQA+P F + NL + N ++
Sbjct: 108 LRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIE 167
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI 299
FR L ++ + ++NN L A F+++P LRT +L +++
Sbjct: 168 DGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 69.3 bits (162), Expect = 2e-11
Identities = 38/145 (26%), Positives = 74/145 (51%), Gaps = 4/145 (2%)
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
++++P + +T RL + N+ + F GL H++ +++ N T++ F +L
Sbjct: 46 LRSVPRNIPRNTERL---DLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDL 102
Query: 287 PALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
L L+L+ + ++ PE F+ + L L L+ NQ++ +PR RG + +L L YN
Sbjct: 103 KELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQ 162
Query: 346 VAELAPELFADLRALETFVMDGNEL 370
++ + F LR LE ++ N +
Sbjct: 163 ISCIEDGAFRALRDLEVLTLNNNNI 187
Score = 63.7 bits (148), Expect = 1e-09
Identities = 44/151 (29%), Positives = 67/151 (44%), Gaps = 1/151 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I + F GL ++ +T+ + L +L RLN +F
Sbjct: 65 NNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFL 124
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
T L L+LS+ +I +P AF G ++ L + N+I+ I GAFR L ++ VL+LN
Sbjct: 125 GTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNN 184
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
N I L F P+L + N+ Y D
Sbjct: 185 NNITRLSVASFNHMPKLRTFRLHSNNL-YCD 214
Score = 60.9 bits (141), Expect = 8e-09
Identities = 39/138 (28%), Positives = 67/138 (48%), Gaps = 1/138 (0%)
Query: 137 DVLRSLPK-LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQ 195
++ +LP+ +T RL + F+ L+ ++LS+ +I+ L DAF GL L
Sbjct: 293 EIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNS 352
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L ++ N+I + F GL ++ +L LN N+I L F L L++ N + +
Sbjct: 353 LVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIA 412
Query: 256 SETFRGLDHIQEIKISNN 273
TF L IQ + ++ N
Sbjct: 413 KGTFSPLRAIQTMHLAQN 430
Score = 59.7 bits (138), Expect = 2e-08
Identities = 35/123 (28%), Positives = 61/123 (49%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
+ L I V+P AF L ++++ N+I+ + AF+GL ++ L L N+I LP
Sbjct: 305 IRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELP 364
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
LF L L + N L + F+ L ++ + + +N T+ + FS L A++T
Sbjct: 365 KSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQT 424
Query: 292 LQL 294
+ L
Sbjct: 425 MHL 427
Score = 58.0 bits (134), Expect = 5e-08
Identities = 60/277 (21%), Positives = 109/277 (39%), Gaps = 10/277 (3%)
Query: 102 VFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHAN 161
+ +N I+ + AF+ L + N P + KL L+ + +
Sbjct: 86 LMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRK 145
Query: 162 MFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLS 221
F +K L+L +I+ + D AF L LE L + N I ++ +F + +
Sbjct: 146 AFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFR 205
Query: 222 LNKNRIQ-----ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
L+ N + A + PR+ T +L + +E S +
Sbjct: 206 LHSNNLYCDCHLAWLSDWLRQRPRVGLYTQCMGP-SHLRGHNVAEVQK-REFVCSGHQSF 263
Query: 277 TLKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSP--LRTLSLARNQLRVLPRSVLRGQ 333
+ PA T ++ R E +N P + + L +N ++V+P
Sbjct: 264 MAPSCSVLHCPAACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPY 323
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+L + LS N ++ELAP+ F LR+L + V+ GN++
Sbjct: 324 KKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKI 360
Score = 56.8 bits (131), Expect = 1e-07
Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 1/156 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L LN N I + FA L L +M N ++ F+ L ++ ++++ N
Sbjct: 56 NTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHL 115
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
E +F L L L + I+ +P + F ++ L L NQ+ + R
Sbjct: 116 QLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALR 175
Query: 335 QLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L LTL+ N + L+ F + L TF + N L
Sbjct: 176 DLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 55.2 bits (127), Expect = 4e-07
Identities = 35/124 (28%), Positives = 59/124 (47%), Gaps = 1/124 (0%)
Query: 172 LELSDAKITVLPDDA-FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
L L++ + TVL F L L ++N N+I +I GAF G V + L NR++ +
Sbjct: 538 LRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 597
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
+F L L + N + +++F GL ++ + + +N T+ F L +L
Sbjct: 598 QHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLS 657
Query: 291 TLQL 294
TL L
Sbjct: 658 TLNL 661
Score = 53.2 bits (122), Expect = 2e-06
Identities = 38/153 (24%), Positives = 68/153 (44%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T + N T + L L +L + T+ F + L+ L L+ +
Sbjct: 57 TERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQ 116
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
+ P+ FLG L +L++ EN+I I AFRG ++ L L+ N+I + G F +
Sbjct: 117 LFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRD 176
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L LT+ N+ L +F + ++ ++ +N
Sbjct: 177 LEVLTLNNNNITRLSVASFNHMPKLRTFRLHSN 209
Score = 53.2 bits (122), Expect = 2e-06
Identities = 35/118 (29%), Positives = 54/118 (45%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
+P KL L+ + L + F L L L KIT LP F GL L
Sbjct: 315 IPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSL 374
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
+ L + N+I + AF+ LHN+ +LSL N++Q + G F+ + + + +N F
Sbjct: 375 QLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPF 432
Score = 52.4 bits (120), Expect = 3e-06
Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 1/147 (0%)
Query: 80 ECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADA-FKGLGITALMMFNAGAQTTVPVDV 138
+CS L+ + + + + + N L A FK L + F+ T +
Sbjct: 518 DCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGA 577
Query: 139 LRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
+ L + R + MF LK L L +IT + +D+F+GL+ + L++
Sbjct: 578 FEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSL 637
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKN 225
++N+I + GAF LH+++ L+L N
Sbjct: 638 YDNQITTVAPGAFDTLHSLSTLNLLAN 664
Score = 49.6 bits (113), Expect = 2e-05
Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 1/108 (0%)
Query: 265 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLR 323
I EI++ N + FS LR + L + I EL P+ F L +L L N++
Sbjct: 302 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 361
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
LP+S+ G L L L+ N + L + F DL L + N+LQ
Sbjct: 362 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQ 409
Score = 48.4 bits (110), Expect = 4e-05
Identities = 33/107 (30%), Positives = 54/107 (50%), Gaps = 4/107 (3%)
Query: 142 LPKLT-HFRLNAGRNITLHAN-MFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
+P+ T RLN L A +F P L+ + S+ KIT + + AF G + + ++ +
Sbjct: 531 IPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLT 590
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLF--ASTPRLLNL 244
N + N+ F+GL ++ L L NRI + F S+ RLL+L
Sbjct: 591 SNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSL 637
Score = 48.0 bits (109), Expect = 6e-05
Identities = 31/129 (24%), Positives = 61/129 (47%), Gaps = 1/129 (0%)
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
+T + L +N I+ +P G F+ +L + + N L + F+GL + + + N
Sbjct: 302 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 361
Query: 277 TLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
L +++F L +L+ L L+ + I L + F L LSL N+L+ + +
Sbjct: 362 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRA 421
Query: 336 LTSLTLSYN 344
+ ++ L+ N
Sbjct: 422 IQTMHLAQN 430
Score = 48.0 bits (109), Expect = 6e-05
Identities = 39/129 (30%), Positives = 58/129 (44%), Gaps = 7/129 (5%)
Query: 218 TVLSLNKNRIQALPAGLFASTPR-LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
TV+ + ++ LP G+ PR + L + N F + E H+ I +SNN
Sbjct: 736 TVVRCSNKGLKVLPKGI----PRDVTELYLDGNQFTLVPKE-LSNYKHLTLIDLSNNRIS 790
Query: 277 TLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
TL FSN+ L TL L + +R + P F LR LSL N + V+P +
Sbjct: 791 TLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSA 850
Query: 336 LTSLTLSYN 344
L+ L + N
Sbjct: 851 LSHLAIGAN 859
Score = 46.0 bits (104), Expect = 2e-04
Identities = 24/81 (29%), Positives = 40/81 (49%)
Query: 292 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAP 351
L LD + +P+E + L + L+ N++ L TQL +L LSYN + + P
Sbjct: 759 LYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPP 818
Query: 352 ELFADLRALETFVMDGNELQV 372
F L++L + GN++ V
Sbjct: 819 RTFDGLKSLRLLSLHGNDISV 839
Score = 43.6 bits (98), Expect = 0.001
Identities = 27/114 (23%), Positives = 50/114 (43%)
Query: 138 VLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
+ + LP+L + + + F + + L+ ++ + F GL L+ L
Sbjct: 553 IFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLM 612
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
+ N I + +F GL +V +LSL N+I + G F + L L ++ N F
Sbjct: 613 LRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPF 666
Score = 43.6 bits (98), Expect = 0.001
Identities = 28/97 (28%), Positives = 46/97 (47%)
Query: 153 GRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR 212
G TL +N L ++LS+ +I+ L + +F + L L + N + I F
Sbjct: 763 GNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFD 822
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
GL ++ +LSL+ N I +P G F L +L + N
Sbjct: 823 GLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGAN 859
Score = 43.2 bits (97), Expect = 0.002
Identities = 32/110 (29%), Positives = 51/110 (46%)
Query: 116 KGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELS 175
KG+ ++ G Q T+ L + LT L+ R TL F+N L L LS
Sbjct: 750 KGIPRDVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILS 809
Query: 176 DAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
++ +P F GL L L++ N+I+ + GAF L ++ L++ N
Sbjct: 810 YNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGAN 859
Score = 42.7 bits (96), Expect = 0.002
Identities = 23/79 (29%), Positives = 41/79 (51%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
++T++ L+ NRI L F++ +LL L + N R + TF GL ++ + + N
Sbjct: 778 HLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDI 837
Query: 276 LTLKEAVFSNLPALRTLQL 294
+ E F++L AL L +
Sbjct: 838 SVVPEGAFNDLSALSHLAI 856
Score = 42.3 bits (95), Expect = 0.003
Identities = 29/127 (22%), Positives = 55/127 (43%), Gaps = 2/127 (1%)
Query: 244 LTMMRNSFRYLDSE-TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL 302
L + N F L++ F+ L +++I SNN ++E F + + L + + +
Sbjct: 538 LRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 597
Query: 303 PEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALE 361
+ L+TL L N++ + G + + L+L N + +AP F L +L
Sbjct: 598 QHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLS 657
Query: 362 TFVMDGN 368
T + N
Sbjct: 658 TLNLLAN 664
Score = 40.3 bits (90), Expect = 0.012
Identities = 31/129 (24%), Positives = 57/129 (44%), Gaps = 1/129 (0%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
+ ++ + +N I I GAF + + L+ N+I L F L +L + N
Sbjct: 302 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 361
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSP 311
L F GL +Q + ++ N L+ F +L L L L + ++ + + F
Sbjct: 362 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRA 421
Query: 312 LRTLSLARN 320
++T+ LA+N
Sbjct: 422 IQTMHLAQN 430
Score = 37.9 bits (84), Expect = 0.062
Identities = 25/97 (25%), Positives = 42/97 (43%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I+ L DAF+GL ++ T +P + L L LNA + L + F
Sbjct: 334 NQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQ 393
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
+ L L L D K+ + F L ++ +++ +N
Sbjct: 394 DLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQN 430
>AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein.
Length = 1525
Score = 76.6 bits (180), Expect = 1e-13
Identities = 48/152 (31%), Positives = 75/152 (49%), Gaps = 1/152 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L+L+ IT + F GL L L + EN+I+ I GAF+ L + L LN+N +Q P
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
LF T +L L + N + + + FRG I+ +++ N +++ F L L
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 292 LQLDLSSIRELPEEFISNSP-LRTLSLARNQL 322
L L+ ++I L ++ P LRT L N L
Sbjct: 180 LTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 72.1 bits (169), Expect = 3e-12
Identities = 50/164 (30%), Positives = 84/164 (51%), Gaps = 3/164 (1%)
Query: 138 VLRSLPKLTHFRLNA-GRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQ 195
V R++P+ T RL+ G NIT + FA L+ L+L + KI+ + AF L LE+
Sbjct: 49 VPRNIPRNTE-RLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELER 107
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L + N + F G + L L++N+IQA+P F + NL + N ++
Sbjct: 108 LRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIE 167
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI 299
FR L ++ + ++NN L A F+++P LRT +L +++
Sbjct: 168 DGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 69.3 bits (162), Expect = 2e-11
Identities = 38/145 (26%), Positives = 74/145 (51%), Gaps = 4/145 (2%)
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
++++P + +T RL + N+ + F GL H++ +++ N T++ F +L
Sbjct: 46 LRSVPRNIPRNTERL---DLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDL 102
Query: 287 PALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
L L+L+ + ++ PE F+ + L L L+ NQ++ +PR RG + +L L YN
Sbjct: 103 KELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQ 162
Query: 346 VAELAPELFADLRALETFVMDGNEL 370
++ + F LR LE ++ N +
Sbjct: 163 ISCIEDGAFRALRDLEVLTLNNNNI 187
Score = 63.7 bits (148), Expect = 1e-09
Identities = 44/151 (29%), Positives = 67/151 (44%), Gaps = 1/151 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I + F GL ++ +T+ + L +L RLN +F
Sbjct: 65 NNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFL 124
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
T L L+LS+ +I +P AF G ++ L + N+I+ I GAFR L ++ VL+LN
Sbjct: 125 GTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNN 184
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
N I L F P+L + N+ Y D
Sbjct: 185 NNITRLSVASFNHMPKLRTFRLHSNNL-YCD 214
Score = 60.9 bits (141), Expect = 8e-09
Identities = 39/138 (28%), Positives = 67/138 (48%), Gaps = 1/138 (0%)
Query: 137 DVLRSLPK-LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQ 195
++ +LP+ +T RL + F+ L+ ++LS+ +I+ L DAF GL L
Sbjct: 297 EIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNS 356
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L ++ N+I + F GL ++ +L LN N+I L F L L++ N + +
Sbjct: 357 LVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIA 416
Query: 256 SETFRGLDHIQEIKISNN 273
TF L IQ + ++ N
Sbjct: 417 KGTFSPLRAIQTMHLAQN 434
Score = 59.7 bits (138), Expect = 2e-08
Identities = 35/123 (28%), Positives = 61/123 (49%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
+ L I V+P AF L ++++ N+I+ + AF+GL ++ L L N+I LP
Sbjct: 309 IRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELP 368
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
LF L L + N L + F+ L ++ + + +N T+ + FS L A++T
Sbjct: 369 KSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQT 428
Query: 292 LQL 294
+ L
Sbjct: 429 MHL 431
Score = 56.8 bits (131), Expect = 1e-07
Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 1/156 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L LN N I + FA L L +M N ++ F+ L ++ ++++ N
Sbjct: 56 NTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHL 115
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
E +F L L L + I+ +P + F ++ L L NQ+ + R
Sbjct: 116 QLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALR 175
Query: 335 QLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L LTL+ N + L+ F + L TF + N L
Sbjct: 176 DLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 56.4 bits (130), Expect = 2e-07
Identities = 59/279 (21%), Positives = 110/279 (39%), Gaps = 10/279 (3%)
Query: 102 VFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHAN 161
+ +N I+ + AF+ L + N P + KL L+ + +
Sbjct: 86 LMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRK 145
Query: 162 MFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLS 221
F +K L+L +I+ + D AF L LE L + N I ++ +F + +
Sbjct: 146 AFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFR 205
Query: 222 LNKNRIQ-----ALPAGLFASTPR--LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV 274
L+ N + A + PR L M + R + + + + + +
Sbjct: 206 LHSNNLYCDCHLAWLSDWLRKRPRVGLYTQCMGPSHLRGHNVAEVQKREFVCSDEEEGHQ 265
Query: 275 PLTLKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSP--LRTLSLARNQLRVLPRSVLR 331
+ PA T ++ R E +N P + + L +N ++V+P
Sbjct: 266 SFMAPSCSVLHCPAACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFS 325
Query: 332 GQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+L + LS N ++ELAP+ F LR+L + V+ GN++
Sbjct: 326 PYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKI 364
Score = 55.2 bits (127), Expect = 4e-07
Identities = 35/124 (28%), Positives = 59/124 (47%), Gaps = 1/124 (0%)
Query: 172 LELSDAKITVLPDDA-FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
L L++ + TVL F L L ++N N+I +I GAF G V + L NR++ +
Sbjct: 534 LRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 593
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
+F L L + N + +++F GL ++ + + +N T+ F L +L
Sbjct: 594 QHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLS 653
Query: 291 TLQL 294
TL L
Sbjct: 654 TLNL 657
Score = 53.2 bits (122), Expect = 2e-06
Identities = 38/153 (24%), Positives = 68/153 (44%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T + N T + L L +L + T+ F + L+ L L+ +
Sbjct: 57 TERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQ 116
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
+ P+ FLG L +L++ EN+I I AFRG ++ L L+ N+I + G F +
Sbjct: 117 LFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRD 176
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L LT+ N+ L +F + ++ ++ +N
Sbjct: 177 LEVLTLNNNNITRLSVASFNHMPKLRTFRLHSN 209
Score = 53.2 bits (122), Expect = 2e-06
Identities = 35/118 (29%), Positives = 54/118 (45%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
+P KL L+ + L + F L L L KIT LP F GL L
Sbjct: 319 IPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSL 378
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
+ L + N+I + AF+ LHN+ +LSL N++Q + G F+ + + + +N F
Sbjct: 379 QLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPF 436
Score = 52.4 bits (120), Expect = 3e-06
Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 1/147 (0%)
Query: 80 ECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADA-FKGLGITALMMFNAGAQTTVPVDV 138
+CS L+ + + + + + N L A FK L + F+ T +
Sbjct: 514 DCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGA 573
Query: 139 LRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
+ L + R + MF LK L L +IT + +D+F+GL+ + L++
Sbjct: 574 FEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSL 633
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKN 225
++N+I + GAF LH+++ L+L N
Sbjct: 634 YDNQITTVAPGAFDTLHSLSTLNLLAN 660
Score = 49.6 bits (113), Expect = 2e-05
Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 1/108 (0%)
Query: 265 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLR 323
I EI++ N + FS LR + L + I EL P+ F L +L L N++
Sbjct: 306 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 365
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
LP+S+ G L L L+ N + L + F DL L + N+LQ
Sbjct: 366 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQ 413
Score = 48.4 bits (110), Expect = 4e-05
Identities = 33/107 (30%), Positives = 54/107 (50%), Gaps = 4/107 (3%)
Query: 142 LPKLT-HFRLNAGRNITLHAN-MFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
+P+ T RLN L A +F P L+ + S+ KIT + + AF G + + ++ +
Sbjct: 527 IPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLT 586
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLF--ASTPRLLNL 244
N + N+ F+GL ++ L L NRI + F S+ RLL+L
Sbjct: 587 SNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSL 633
Score = 48.0 bits (109), Expect = 6e-05
Identities = 31/129 (24%), Positives = 61/129 (47%), Gaps = 1/129 (0%)
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
+T + L +N I+ +P G F+ +L + + N L + F+GL + + + N
Sbjct: 306 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 365
Query: 277 TLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
L +++F L +L+ L L+ + I L + F L LSL N+L+ + +
Sbjct: 366 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRA 425
Query: 336 LTSLTLSYN 344
+ ++ L+ N
Sbjct: 426 IQTMHLAQN 434
Score = 48.0 bits (109), Expect = 6e-05
Identities = 39/129 (30%), Positives = 58/129 (44%), Gaps = 7/129 (5%)
Query: 218 TVLSLNKNRIQALPAGLFASTPR-LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
TV+ + ++ LP G+ PR + L + N F + E H+ I +SNN
Sbjct: 732 TVVRCSNKGLKVLPKGI----PRDVTELYLDGNQFTLVPKE-LSNYKHLTLIDLSNNRIS 786
Query: 277 TLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
TL FSN+ L TL L + +R + P F LR LSL N + V+P +
Sbjct: 787 TLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSA 846
Query: 336 LTSLTLSYN 344
L+ L + N
Sbjct: 847 LSHLAIGAN 855
Score = 46.0 bits (104), Expect = 2e-04
Identities = 24/81 (29%), Positives = 40/81 (49%)
Query: 292 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAP 351
L LD + +P+E + L + L+ N++ L TQL +L LSYN + + P
Sbjct: 755 LYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPP 814
Query: 352 ELFADLRALETFVMDGNELQV 372
F L++L + GN++ V
Sbjct: 815 RTFDGLKSLRLLSLHGNDISV 835
Score = 43.6 bits (98), Expect = 0.001
Identities = 27/114 (23%), Positives = 50/114 (43%)
Query: 138 VLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
+ + LP+L + + + F + + L+ ++ + F GL L+ L
Sbjct: 549 IFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLM 608
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
+ N I + +F GL +V +LSL N+I + G F + L L ++ N F
Sbjct: 609 LRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPF 662
Score = 43.6 bits (98), Expect = 0.001
Identities = 28/97 (28%), Positives = 46/97 (47%)
Query: 153 GRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR 212
G TL +N L ++LS+ +I+ L + +F + L L + N + I F
Sbjct: 759 GNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFD 818
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
GL ++ +LSL+ N I +P G F L +L + N
Sbjct: 819 GLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGAN 855
Score = 43.2 bits (97), Expect = 0.002
Identities = 32/110 (29%), Positives = 51/110 (46%)
Query: 116 KGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELS 175
KG+ ++ G Q T+ L + LT L+ R TL F+N L L LS
Sbjct: 746 KGIPRDVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILS 805
Query: 176 DAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
++ +P F GL L L++ N+I+ + GAF L ++ L++ N
Sbjct: 806 YNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGAN 855
Score = 42.7 bits (96), Expect = 0.002
Identities = 23/79 (29%), Positives = 41/79 (51%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
++T++ L+ NRI L F++ +LL L + N R + TF GL ++ + + N
Sbjct: 774 HLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDI 833
Query: 276 LTLKEAVFSNLPALRTLQL 294
+ E F++L AL L +
Sbjct: 834 SVVPEGAFNDLSALSHLAI 852
Score = 42.3 bits (95), Expect = 0.003
Identities = 29/127 (22%), Positives = 55/127 (43%), Gaps = 2/127 (1%)
Query: 244 LTMMRNSFRYLDSE-TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL 302
L + N F L++ F+ L +++I SNN ++E F + + L + + +
Sbjct: 534 LRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 593
Query: 303 PEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALE 361
+ L+TL L N++ + G + + L+L N + +AP F L +L
Sbjct: 594 QHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLS 653
Query: 362 TFVMDGN 368
T + N
Sbjct: 654 TLNLLAN 660
Score = 40.3 bits (90), Expect = 0.012
Identities = 31/129 (24%), Positives = 57/129 (44%), Gaps = 1/129 (0%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
+ ++ + +N I I GAF + + L+ N+I L F L +L + N
Sbjct: 306 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 365
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSP 311
L F GL +Q + ++ N L+ F +L L L L + ++ + + F
Sbjct: 366 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRA 425
Query: 312 LRTLSLARN 320
++T+ LA+N
Sbjct: 426 IQTMHLAQN 434
Score = 38.7 bits (86), Expect = 0.035
Identities = 40/183 (21%), Positives = 73/183 (39%), Gaps = 7/183 (3%)
Query: 21 CTDGEELNYQCSRPSTNLIVGARPRDYVN--IDCMGGELVCAEFPEIDTPATTQLPSLSL 78
C+D EE + PS +++ N +DC G L EI T + + L
Sbjct: 257 CSDEEEGHQSFMAPSCSVLHCPAACTCSNNIVDCRGKGLT-----EIPTNLPETITEIRL 311
Query: 79 RECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDV 138
+ ++ + + + + + N I+ L DAF+GL ++ T +P +
Sbjct: 312 EQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSL 371
Query: 139 LRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
L L LNA + L + F + L L L D K+ + F L ++ +++
Sbjct: 372 FEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHL 431
Query: 199 WEN 201
+N
Sbjct: 432 AQN 434
>AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellular
slit protein Slit2 protein.
Length = 1521
Score = 76.6 bits (180), Expect = 1e-13
Identities = 48/152 (31%), Positives = 75/152 (49%), Gaps = 1/152 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L+L+ IT + F GL L L + EN+I+ I GAF+ L + L LN+N +Q P
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
LF T +L L + N + + + FRG I+ +++ N +++ F L L
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 292 LQLDLSSIRELPEEFISNSP-LRTLSLARNQL 322
L L+ ++I L ++ P LRT L N L
Sbjct: 180 LTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 72.1 bits (169), Expect = 3e-12
Identities = 50/164 (30%), Positives = 84/164 (51%), Gaps = 3/164 (1%)
Query: 138 VLRSLPKLTHFRLNA-GRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQ 195
V R++P+ T RL+ G NIT + FA L+ L+L + KI+ + AF L LE+
Sbjct: 49 VPRNIPRNTE-RLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELER 107
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L + N + F G + L L++N+IQA+P F + NL + N ++
Sbjct: 108 LRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIE 167
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI 299
FR L ++ + ++NN L A F+++P LRT +L +++
Sbjct: 168 DGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 69.3 bits (162), Expect = 2e-11
Identities = 38/145 (26%), Positives = 74/145 (51%), Gaps = 4/145 (2%)
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
++++P + +T RL + N+ + F GL H++ +++ N T++ F +L
Sbjct: 46 LRSVPRNIPRNTERL---DLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDL 102
Query: 287 PALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
L L+L+ + ++ PE F+ + L L L+ NQ++ +PR RG + +L L YN
Sbjct: 103 KELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQ 162
Query: 346 VAELAPELFADLRALETFVMDGNEL 370
++ + F LR LE ++ N +
Sbjct: 163 ISCIEDGAFRALRDLEVLTLNNNNI 187
Score = 63.7 bits (148), Expect = 1e-09
Identities = 44/151 (29%), Positives = 67/151 (44%), Gaps = 1/151 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I + F GL ++ +T+ + L +L RLN +F
Sbjct: 65 NNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFL 124
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
T L L+LS+ +I +P AF G ++ L + N+I+ I GAFR L ++ VL+LN
Sbjct: 125 GTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNN 184
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
N I L F P+L + N+ Y D
Sbjct: 185 NNITRLSVASFNHMPKLRTFRLHSNNL-YCD 214
Score = 60.9 bits (141), Expect = 8e-09
Identities = 39/138 (28%), Positives = 67/138 (48%), Gaps = 1/138 (0%)
Query: 137 DVLRSLPK-LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQ 195
++ +LP+ +T RL + F+ L+ ++LS+ +I+ L DAF GL L
Sbjct: 293 EIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNS 352
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L ++ N+I + F GL ++ +L LN N+I L F L L++ N + +
Sbjct: 353 LVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIA 412
Query: 256 SETFRGLDHIQEIKISNN 273
TF L IQ + ++ N
Sbjct: 413 KGTFSPLRAIQTMHLAQN 430
Score = 59.7 bits (138), Expect = 2e-08
Identities = 35/123 (28%), Positives = 61/123 (49%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
+ L I V+P AF L ++++ N+I+ + AF+GL ++ L L N+I LP
Sbjct: 305 IRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELP 364
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
LF L L + N L + F+ L ++ + + +N T+ + FS L A++T
Sbjct: 365 KSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQT 424
Query: 292 LQL 294
+ L
Sbjct: 425 MHL 427
Score = 58.0 bits (134), Expect = 5e-08
Identities = 60/277 (21%), Positives = 109/277 (39%), Gaps = 10/277 (3%)
Query: 102 VFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHAN 161
+ +N I+ + AF+ L + N P + KL L+ + +
Sbjct: 86 LMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRK 145
Query: 162 MFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLS 221
F +K L+L +I+ + D AF L LE L + N I ++ +F + +
Sbjct: 146 AFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFR 205
Query: 222 LNKNRIQ-----ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
L+ N + A + PR+ T +L + +E S +
Sbjct: 206 LHSNNLYCDCHLAWLSDWLRQRPRVGLYTQCMGP-SHLRGHNVAEVQK-REFVCSGHQSF 263
Query: 277 TLKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSP--LRTLSLARNQLRVLPRSVLRGQ 333
+ PA T ++ R E +N P + + L +N ++V+P
Sbjct: 264 MAPSCSVLHCPAACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPY 323
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+L + LS N ++ELAP+ F LR+L + V+ GN++
Sbjct: 324 KKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKI 360
Score = 56.8 bits (131), Expect = 1e-07
Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 1/156 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L LN N I + FA L L +M N ++ F+ L ++ ++++ N
Sbjct: 56 NTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHL 115
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
E +F L L L + I+ +P + F ++ L L NQ+ + R
Sbjct: 116 QLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALR 175
Query: 335 QLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L LTL+ N + L+ F + L TF + N L
Sbjct: 176 DLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 56.4 bits (130), Expect = 2e-07
Identities = 35/124 (28%), Positives = 60/124 (48%), Gaps = 1/124 (0%)
Query: 172 LELSDAKITVLPDDA-FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
L L++ + TVL F L L ++N N+I +I GAF G V + L NR++ +
Sbjct: 530 LRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 589
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
+F + NL + N + +++F GL ++ + + +N T+ F L +L
Sbjct: 590 QHKMFKGLEKPQNLMLRSNRITCVGNDSFIGLSSVRMLSLYDNQITTVAPGAFDTLHSLS 649
Query: 291 TLQL 294
TL L
Sbjct: 650 TLNL 653
Score = 53.2 bits (122), Expect = 2e-06
Identities = 38/153 (24%), Positives = 68/153 (44%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T + N T + L L +L + T+ F + L+ L L+ +
Sbjct: 57 TERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQ 116
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
+ P+ FLG L +L++ EN+I I AFRG ++ L L+ N+I + G F +
Sbjct: 117 LFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRD 176
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L LT+ N+ L +F + ++ ++ +N
Sbjct: 177 LEVLTLNNNNITRLSVASFNHMPKLRTFRLHSN 209
Score = 53.2 bits (122), Expect = 2e-06
Identities = 35/118 (29%), Positives = 54/118 (45%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
+P KL L+ + L + F L L L KIT LP F GL L
Sbjct: 315 IPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSL 374
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
+ L + N+I + AF+ LHN+ +LSL N++Q + G F+ + + + +N F
Sbjct: 375 QLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPF 432
Score = 49.6 bits (113), Expect = 2e-05
Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 1/108 (0%)
Query: 265 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLR 323
I EI++ N + FS LR + L + I EL P+ F L +L L N++
Sbjct: 302 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 361
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
LP+S+ G L L L+ N + L + F DL L + N+LQ
Sbjct: 362 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQ 409
Score = 48.8 bits (111), Expect = 3e-05
Identities = 34/147 (23%), Positives = 65/147 (44%), Gaps = 1/147 (0%)
Query: 80 ECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADA-FKGLGITALMMFNAGAQTTVPVDV 138
+CS L+ + + + + + N L A FK L + F+ T +
Sbjct: 510 DCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGA 569
Query: 139 LRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
+ L + R + MF + L L +IT + +D+F+GL+ + L++
Sbjct: 570 FEGASGVNEILLTSNRLENVQHKMFKGLEKPQNLMLRSNRITCVGNDSFIGLSSVRMLSL 629
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKN 225
++N+I + GAF LH+++ L+L N
Sbjct: 630 YDNQITTVAPGAFDTLHSLSTLNLLAN 656
Score = 48.0 bits (109), Expect = 6e-05
Identities = 31/129 (24%), Positives = 61/129 (47%), Gaps = 1/129 (0%)
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
+T + L +N I+ +P G F+ +L + + N L + F+GL + + + N
Sbjct: 302 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 361
Query: 277 TLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
L +++F L +L+ L L+ + I L + F L LSL N+L+ + +
Sbjct: 362 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRA 421
Query: 336 LTSLTLSYN 344
+ ++ L+ N
Sbjct: 422 IQTMHLAQN 430
Score = 48.0 bits (109), Expect = 6e-05
Identities = 39/129 (30%), Positives = 58/129 (44%), Gaps = 7/129 (5%)
Query: 218 TVLSLNKNRIQALPAGLFASTPR-LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
TV+ + ++ LP G+ PR + L + N F + E H+ I +SNN
Sbjct: 728 TVVRCSNKGLKVLPKGI----PRDVTELYLDGNQFTLVPKE-LSNYKHLTLIDLSNNRIS 782
Query: 277 TLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
TL FSN+ L TL L + +R + P F LR LSL N + V+P +
Sbjct: 783 TLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSA 842
Query: 336 LTSLTLSYN 344
L+ L + N
Sbjct: 843 LSHLAIGAN 851
Score = 46.0 bits (104), Expect = 2e-04
Identities = 24/81 (29%), Positives = 40/81 (49%)
Query: 292 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAP 351
L LD + +P+E + L + L+ N++ L TQL +L LSYN + + P
Sbjct: 751 LYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPP 810
Query: 352 ELFADLRALETFVMDGNELQV 372
F L++L + GN++ V
Sbjct: 811 RTFDGLKSLRLLSLHGNDISV 831
Score = 45.6 bits (103), Expect = 3e-04
Identities = 33/134 (24%), Positives = 57/134 (42%), Gaps = 2/134 (1%)
Query: 142 LPKLT-HFRLNAGRNITLHAN-MFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
+P+ T RLN L A +F P L+ + S+ KIT + + AF G + + ++ +
Sbjct: 523 IPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLT 582
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
N + N+ F+GL L L NRI + F + L++ N + F
Sbjct: 583 SNRLENVQHKMFKGLEKPQNLMLRSNRITCVGNDSFIGLSSVRMLSLYDNQITTVAPGAF 642
Query: 260 RGLDHIQEIKISNN 273
L + + + N
Sbjct: 643 DTLHSLSTLNLLAN 656
Score = 45.6 bits (103), Expect = 3e-04
Identities = 34/127 (26%), Positives = 55/127 (43%), Gaps = 2/127 (1%)
Query: 220 LSLNKNRIQALPA-GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTL 278
L LN N L A G+F P+L + N ++ F G + EI +++N +
Sbjct: 530 LRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 589
Query: 279 KEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLT 337
+ +F L + L L + I + + FI S +R LSL NQ+ + L+
Sbjct: 590 QHKMFKGLEKPQNLMLRSNRITCVGNDSFIGLSSVRMLSLYDNQITTVAPGAFDTLHSLS 649
Query: 338 SLTLSYN 344
+L L N
Sbjct: 650 TLNLLAN 656
Score = 43.6 bits (98), Expect = 0.001
Identities = 28/97 (28%), Positives = 46/97 (47%)
Query: 153 GRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR 212
G TL +N L ++LS+ +I+ L + +F + L L + N + I F
Sbjct: 755 GNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFD 814
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
GL ++ +LSL+ N I +P G F L +L + N
Sbjct: 815 GLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGAN 851
Score = 43.2 bits (97), Expect = 0.002
Identities = 32/110 (29%), Positives = 51/110 (46%)
Query: 116 KGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELS 175
KG+ ++ G Q T+ L + LT L+ R TL F+N L L LS
Sbjct: 742 KGIPRDVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILS 801
Query: 176 DAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
++ +P F GL L L++ N+I+ + GAF L ++ L++ N
Sbjct: 802 YNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGAN 851
Score = 42.7 bits (96), Expect = 0.002
Identities = 23/79 (29%), Positives = 41/79 (51%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
++T++ L+ NRI L F++ +LL L + N R + TF GL ++ + + N
Sbjct: 770 HLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDI 829
Query: 276 LTLKEAVFSNLPALRTLQL 294
+ E F++L AL L +
Sbjct: 830 SVVPEGAFNDLSALSHLAI 848
Score = 41.5 bits (93), Expect = 0.005
Identities = 26/114 (22%), Positives = 49/114 (42%)
Query: 138 VLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
+ + LP+L + + + F + + L+ ++ + F GL + L
Sbjct: 545 IFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLEKPQNLM 604
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
+ N I + +F GL +V +LSL N+I + G F + L L ++ N F
Sbjct: 605 LRSNRITCVGNDSFIGLSSVRMLSLYDNQITTVAPGAFDTLHSLSTLNLLANPF 658
Score = 40.3 bits (90), Expect = 0.012
Identities = 31/129 (24%), Positives = 57/129 (44%), Gaps = 1/129 (0%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
+ ++ + +N I I GAF + + L+ N+I L F L +L + N
Sbjct: 302 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 361
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSP 311
L F GL +Q + ++ N L+ F +L L L L + ++ + + F
Sbjct: 362 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRA 421
Query: 312 LRTLSLARN 320
++T+ LA+N
Sbjct: 422 IQTMHLAQN 430
Score = 37.9 bits (84), Expect = 0.062
Identities = 25/97 (25%), Positives = 42/97 (43%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I+ L DAF+GL ++ T +P + L L LNA + L + F
Sbjct: 334 NQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQ 393
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
+ L L L D K+ + F L ++ +++ +N
Sbjct: 394 DLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQN 430
>AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein.
Length = 1529
Score = 76.6 bits (180), Expect = 1e-13
Identities = 48/152 (31%), Positives = 75/152 (49%), Gaps = 1/152 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L+L+ IT + F GL L L + EN+I+ I GAF+ L + L LN+N +Q P
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
LF T +L L + N + + + FRG I+ +++ N +++ F L L
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 292 LQLDLSSIRELPEEFISNSP-LRTLSLARNQL 322
L L+ ++I L ++ P LRT L N L
Sbjct: 180 LTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 72.1 bits (169), Expect = 3e-12
Identities = 50/164 (30%), Positives = 84/164 (51%), Gaps = 3/164 (1%)
Query: 138 VLRSLPKLTHFRLNA-GRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQ 195
V R++P+ T RL+ G NIT + FA L+ L+L + KI+ + AF L LE+
Sbjct: 49 VPRNIPRNTE-RLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELER 107
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L + N + F G + L L++N+IQA+P F + NL + N ++
Sbjct: 108 LRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIE 167
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI 299
FR L ++ + ++NN L A F+++P LRT +L +++
Sbjct: 168 DGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 69.3 bits (162), Expect = 2e-11
Identities = 38/145 (26%), Positives = 74/145 (51%), Gaps = 4/145 (2%)
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
++++P + +T RL + N+ + F GL H++ +++ N T++ F +L
Sbjct: 46 LRSVPRNIPRNTERL---DLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDL 102
Query: 287 PALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
L L+L+ + ++ PE F+ + L L L+ NQ++ +PR RG + +L L YN
Sbjct: 103 KELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQ 162
Query: 346 VAELAPELFADLRALETFVMDGNEL 370
++ + F LR LE ++ N +
Sbjct: 163 ISCIEDGAFRALRDLEVLTLNNNNI 187
Score = 63.7 bits (148), Expect = 1e-09
Identities = 44/151 (29%), Positives = 67/151 (44%), Gaps = 1/151 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I + F GL ++ +T+ + L +L RLN +F
Sbjct: 65 NNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFL 124
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
T L L+LS+ +I +P AF G ++ L + N+I+ I GAFR L ++ VL+LN
Sbjct: 125 GTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNN 184
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
N I L F P+L + N+ Y D
Sbjct: 185 NNITRLSVASFNHMPKLRTFRLHSNNL-YCD 214
Score = 60.9 bits (141), Expect = 8e-09
Identities = 39/138 (28%), Positives = 67/138 (48%), Gaps = 1/138 (0%)
Query: 137 DVLRSLPK-LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQ 195
++ +LP+ +T RL + F+ L+ ++LS+ +I+ L DAF GL L
Sbjct: 293 EIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNS 352
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L ++ N+I + F GL ++ +L LN N+I L F L L++ N + +
Sbjct: 353 LVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIA 412
Query: 256 SETFRGLDHIQEIKISNN 273
TF L IQ + ++ N
Sbjct: 413 KGTFSPLRAIQTMHLAQN 430
Score = 59.7 bits (138), Expect = 2e-08
Identities = 35/123 (28%), Positives = 61/123 (49%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
+ L I V+P AF L ++++ N+I+ + AF+GL ++ L L N+I LP
Sbjct: 305 IRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELP 364
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
LF L L + N L + F+ L ++ + + +N T+ + FS L A++T
Sbjct: 365 KSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQT 424
Query: 292 LQL 294
+ L
Sbjct: 425 MHL 427
Score = 58.0 bits (134), Expect = 5e-08
Identities = 60/277 (21%), Positives = 109/277 (39%), Gaps = 10/277 (3%)
Query: 102 VFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHAN 161
+ +N I+ + AF+ L + N P + KL L+ + +
Sbjct: 86 LMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRK 145
Query: 162 MFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLS 221
F +K L+L +I+ + D AF L LE L + N I ++ +F + +
Sbjct: 146 AFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFR 205
Query: 222 LNKNRIQ-----ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
L+ N + A + PR+ T +L + +E S +
Sbjct: 206 LHSNNLYCDCHLAWLSDWLRQRPRVGLYTQCMGP-SHLRGHNVAEVQK-REFVCSGHQSF 263
Query: 277 TLKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSP--LRTLSLARNQLRVLPRSVLRGQ 333
+ PA T ++ R E +N P + + L +N ++V+P
Sbjct: 264 MAPSCSVLHCPAACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPY 323
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+L + LS N ++ELAP+ F LR+L + V+ GN++
Sbjct: 324 KKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKI 360
Score = 56.8 bits (131), Expect = 1e-07
Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 1/156 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L LN N I + FA L L +M N ++ F+ L ++ ++++ N
Sbjct: 56 NTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHL 115
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
E +F L L L + I+ +P + F ++ L L NQ+ + R
Sbjct: 116 QLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALR 175
Query: 335 QLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L LTL+ N + L+ F + L TF + N L
Sbjct: 176 DLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 55.2 bits (127), Expect = 4e-07
Identities = 35/124 (28%), Positives = 59/124 (47%), Gaps = 1/124 (0%)
Query: 172 LELSDAKITVLPDDA-FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
L L++ + TVL F L L ++N N+I +I GAF G V + L NR++ +
Sbjct: 538 LRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 597
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
+F L L + N + +++F GL ++ + + +N T+ F L +L
Sbjct: 598 QHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLS 657
Query: 291 TLQL 294
TL L
Sbjct: 658 TLNL 661
Score = 53.2 bits (122), Expect = 2e-06
Identities = 38/153 (24%), Positives = 68/153 (44%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T + N T + L L +L + T+ F + L+ L L+ +
Sbjct: 57 TERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQ 116
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
+ P+ FLG L +L++ EN+I I AFRG ++ L L+ N+I + G F +
Sbjct: 117 LFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRD 176
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L LT+ N+ L +F + ++ ++ +N
Sbjct: 177 LEVLTLNNNNITRLSVASFNHMPKLRTFRLHSN 209
Score = 53.2 bits (122), Expect = 2e-06
Identities = 35/118 (29%), Positives = 54/118 (45%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
+P KL L+ + L + F L L L KIT LP F GL L
Sbjct: 315 IPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSL 374
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
+ L + N+I + AF+ LHN+ +LSL N++Q + G F+ + + + +N F
Sbjct: 375 QLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPF 432
Score = 52.4 bits (120), Expect = 3e-06
Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 1/147 (0%)
Query: 80 ECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADA-FKGLGITALMMFNAGAQTTVPVDV 138
+CS L+ + + + + + N L A FK L + F+ T +
Sbjct: 518 DCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGA 577
Query: 139 LRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
+ L + R + MF LK L L +IT + +D+F+GL+ + L++
Sbjct: 578 FEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSL 637
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKN 225
++N+I + GAF LH+++ L+L N
Sbjct: 638 YDNQITTVAPGAFDTLHSLSTLNLLAN 664
Score = 49.6 bits (113), Expect = 2e-05
Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 1/108 (0%)
Query: 265 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLR 323
I EI++ N + FS LR + L + I EL P+ F L +L L N++
Sbjct: 302 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 361
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
LP+S+ G L L L+ N + L + F DL L + N+LQ
Sbjct: 362 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQ 409
Score = 48.4 bits (110), Expect = 4e-05
Identities = 33/107 (30%), Positives = 54/107 (50%), Gaps = 4/107 (3%)
Query: 142 LPKLT-HFRLNAGRNITLHAN-MFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
+P+ T RLN L A +F P L+ + S+ KIT + + AF G + + ++ +
Sbjct: 531 IPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLT 590
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLF--ASTPRLLNL 244
N + N+ F+GL ++ L L NRI + F S+ RLL+L
Sbjct: 591 SNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSL 637
Score = 48.0 bits (109), Expect = 6e-05
Identities = 31/129 (24%), Positives = 61/129 (47%), Gaps = 1/129 (0%)
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
+T + L +N I+ +P G F+ +L + + N L + F+GL + + + N
Sbjct: 302 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 361
Query: 277 TLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
L +++F L +L+ L L+ + I L + F L LSL N+L+ + +
Sbjct: 362 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRA 421
Query: 336 LTSLTLSYN 344
+ ++ L+ N
Sbjct: 422 IQTMHLAQN 430
Score = 48.0 bits (109), Expect = 6e-05
Identities = 39/129 (30%), Positives = 58/129 (44%), Gaps = 7/129 (5%)
Query: 218 TVLSLNKNRIQALPAGLFASTPR-LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
TV+ + ++ LP G+ PR + L + N F + E H+ I +SNN
Sbjct: 736 TVVRCSNKGLKVLPKGI----PRDVTELYLDGNQFTLVPKE-LSNYKHLTLIDLSNNRIS 790
Query: 277 TLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQ 335
TL FSN+ L TL L + +R + P F LR LSL N + V+P +
Sbjct: 791 TLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSA 850
Query: 336 LTSLTLSYN 344
L+ L + N
Sbjct: 851 LSHLAIGAN 859
Score = 46.0 bits (104), Expect = 2e-04
Identities = 24/81 (29%), Positives = 40/81 (49%)
Query: 292 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAP 351
L LD + +P+E + L + L+ N++ L TQL +L LSYN + + P
Sbjct: 759 LYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPP 818
Query: 352 ELFADLRALETFVMDGNELQV 372
F L++L + GN++ V
Sbjct: 819 RTFDGLKSLRLLSLHGNDISV 839
Score = 43.6 bits (98), Expect = 0.001
Identities = 27/114 (23%), Positives = 50/114 (43%)
Query: 138 VLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
+ + LP+L + + + F + + L+ ++ + F GL L+ L
Sbjct: 553 IFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLM 612
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
+ N I + +F GL +V +LSL N+I + G F + L L ++ N F
Sbjct: 613 LRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPF 666
Score = 43.6 bits (98), Expect = 0.001
Identities = 28/97 (28%), Positives = 46/97 (47%)
Query: 153 GRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR 212
G TL +N L ++LS+ +I+ L + +F + L L + N + I F
Sbjct: 763 GNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFD 822
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
GL ++ +LSL+ N I +P G F L +L + N
Sbjct: 823 GLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGAN 859
Score = 43.2 bits (97), Expect = 0.002
Identities = 32/110 (29%), Positives = 51/110 (46%)
Query: 116 KGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELS 175
KG+ ++ G Q T+ L + LT L+ R TL F+N L L LS
Sbjct: 750 KGIPRDVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILS 809
Query: 176 DAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
++ +P F GL L L++ N+I+ + GAF L ++ L++ N
Sbjct: 810 YNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGAN 859
Score = 42.7 bits (96), Expect = 0.002
Identities = 23/79 (29%), Positives = 41/79 (51%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
++T++ L+ NRI L F++ +LL L + N R + TF GL ++ + + N
Sbjct: 778 HLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDI 837
Query: 276 LTLKEAVFSNLPALRTLQL 294
+ E F++L AL L +
Sbjct: 838 SVVPEGAFNDLSALSHLAI 856
Score = 42.3 bits (95), Expect = 0.003
Identities = 29/127 (22%), Positives = 55/127 (43%), Gaps = 2/127 (1%)
Query: 244 LTMMRNSFRYLDSE-TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL 302
L + N F L++ F+ L +++I SNN ++E F + + L + + +
Sbjct: 538 LRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 597
Query: 303 PEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALE 361
+ L+TL L N++ + G + + L+L N + +AP F L +L
Sbjct: 598 QHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLS 657
Query: 362 TFVMDGN 368
T + N
Sbjct: 658 TLNLLAN 664
Score = 40.3 bits (90), Expect = 0.012
Identities = 31/129 (24%), Positives = 57/129 (44%), Gaps = 1/129 (0%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
+ ++ + +N I I GAF + + L+ N+I L F L +L + N
Sbjct: 302 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 361
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSP 311
L F GL +Q + ++ N L+ F +L L L L + ++ + + F
Sbjct: 362 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRA 421
Query: 312 LRTLSLARN 320
++T+ LA+N
Sbjct: 422 IQTMHLAQN 430
Score = 37.9 bits (84), Expect = 0.062
Identities = 25/97 (25%), Positives = 42/97 (43%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I+ L DAF+GL ++ T +P + L L LNA + L + F
Sbjct: 334 NQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQ 393
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
+ L L L D K+ + F L ++ +++ +N
Sbjct: 394 DLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQN 430
>CR456360-1|CAG30246.1| 473|Homo sapiens Em:AC007663.1 protein.
Length = 473
Score = 76.2 bits (179), Expect = 2e-13
Identities = 52/172 (30%), Positives = 80/172 (46%), Gaps = 2/172 (1%)
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS-FRYLDSETF 259
N I+++ A +FR N+T+L L+ N + + A F L L + N+ R +D TF
Sbjct: 67 NRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATF 126
Query: 260 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLA 318
GL + + + L +F L AL+ L L ++++ LP++ F L L L
Sbjct: 127 HGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLH 186
Query: 319 RNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
N++ +P RG L L L N VA + P F DL L T + N L
Sbjct: 187 GNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNL 238
Score = 73.7 bits (173), Expect = 1e-12
Identities = 49/170 (28%), Positives = 81/170 (47%), Gaps = 1/170 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQT-TVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N + ++A AF GL + + + AQ +V L +L L+ L +F
Sbjct: 91 NVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLF 150
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
L+YL L D + LPDD F L L L + N I+++ AFRGLH++ L L+
Sbjct: 151 RGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLH 210
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
+NR+ + F RL+ L + N+ L +E L +Q +++++N
Sbjct: 211 QNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDN 260
Score = 67.7 bits (158), Expect = 7e-11
Identities = 54/187 (28%), Positives = 82/187 (43%), Gaps = 3/187 (1%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSD-AKITVLPDDAFLGLNV 192
VP R+ LT L++ + A F L+ L+LSD A++ + F GL
Sbjct: 72 VPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATFHGLGR 131
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
L L++ + + G FRGL + L L N +QALP F L +L + N
Sbjct: 132 LHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRIS 191
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPL 312
+ FRGL + + + N + F +L L TL L +++ LP E + +PL
Sbjct: 192 SVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEAL--APL 249
Query: 313 RTLSLAR 319
R L R
Sbjct: 250 RALQYLR 256
Score = 49.6 bits (113), Expect = 2e-05
Identities = 46/216 (21%), Positives = 84/216 (38%), Gaps = 1/216 (0%)
Query: 81 CSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLR 140
C L + + A + + N I+ + A +F+ ++ ++ +
Sbjct: 43 CPQQGLQAVPVGIPAASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFT 102
Query: 141 SLPKLTHFRLNAGRNI-TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
L L L+ + ++ F L L L + L F GL L+ L +
Sbjct: 103 GLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQ 162
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
+N + + FR L N+T L L+ NRI ++P F L L + +N ++ F
Sbjct: 163 DNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAF 222
Query: 260 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD 295
R L + + + N L + L AL+ L+L+
Sbjct: 223 RDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLN 258
Score = 35.9 bits (79), Expect = 0.25
Identities = 38/145 (26%), Positives = 63/145 (43%), Gaps = 25/145 (17%)
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
+QA+P G+ A++ R+ + N ++ + +FR ++ + + +NV + A F+ L
Sbjct: 48 LQAVPVGIPAASQRIF---LHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGL 104
Query: 287 PALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAV 346
L QLDLS QLR + + G +L +L L +
Sbjct: 105 ALLE--QLDLSD--------------------NAQLRSVDPATFHGLGRLHTLHLDRCGL 142
Query: 347 AELAPELFADLRALETFVMDGNELQ 371
EL P LF L AL+ + N LQ
Sbjct: 143 QELGPGLFRGLAALQYLYLQDNALQ 167
>BC011787-1|AAH11787.1| 473|Homo sapiens reticulon 4 receptor
protein.
Length = 473
Score = 76.2 bits (179), Expect = 2e-13
Identities = 52/172 (30%), Positives = 80/172 (46%), Gaps = 2/172 (1%)
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS-FRYLDSETF 259
N I+++ A +FR N+T+L L+ N + + A F L L + N+ R +D TF
Sbjct: 67 NRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATF 126
Query: 260 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLA 318
GL + + + L +F L AL+ L L ++++ LP++ F L L L
Sbjct: 127 HGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLH 186
Query: 319 RNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
N++ +P RG L L L N VA + P F DL L T + N L
Sbjct: 187 GNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNL 238
Score = 73.7 bits (173), Expect = 1e-12
Identities = 49/170 (28%), Positives = 81/170 (47%), Gaps = 1/170 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQT-TVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N + ++A AF GL + + + AQ +V L +L L+ L +F
Sbjct: 91 NVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLF 150
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
L+YL L D + LPDD F L L L + N I+++ AFRGLH++ L L+
Sbjct: 151 RGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLH 210
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
+NR+ + F RL+ L + N+ L +E L +Q +++++N
Sbjct: 211 QNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDN 260
Score = 67.7 bits (158), Expect = 7e-11
Identities = 54/187 (28%), Positives = 82/187 (43%), Gaps = 3/187 (1%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSD-AKITVLPDDAFLGLNV 192
VP R+ LT L++ + A F L+ L+LSD A++ + F GL
Sbjct: 72 VPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATFHGLGR 131
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
L L++ + + G FRGL + L L N +QALP F L +L + N
Sbjct: 132 LHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRIS 191
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPL 312
+ FRGL + + + N + F +L L TL L +++ LP E + +PL
Sbjct: 192 SVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEAL--APL 249
Query: 313 RTLSLAR 319
R L R
Sbjct: 250 RALQYLR 256
Score = 49.6 bits (113), Expect = 2e-05
Identities = 46/216 (21%), Positives = 84/216 (38%), Gaps = 1/216 (0%)
Query: 81 CSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLR 140
C L + + A + + N I+ + A +F+ ++ ++ +
Sbjct: 43 CPQQGLQAVPVGIPAASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFT 102
Query: 141 SLPKLTHFRLNAGRNI-TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
L L L+ + ++ F L L L + L F GL L+ L +
Sbjct: 103 GLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQ 162
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
+N + + FR L N+T L L+ NRI ++P F L L + +N ++ F
Sbjct: 163 DNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAF 222
Query: 260 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD 295
R L + + + N L + L AL+ L+L+
Sbjct: 223 RDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLN 258
Score = 35.9 bits (79), Expect = 0.25
Identities = 38/145 (26%), Positives = 63/145 (43%), Gaps = 25/145 (17%)
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
+QA+P G+ A++ R+ + N ++ + +FR ++ + + +NV + A F+ L
Sbjct: 48 LQAVPVGIPAASQRIF---LHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGL 104
Query: 287 PALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAV 346
L QLDLS QLR + + G +L +L L +
Sbjct: 105 ALLE--QLDLSD--------------------NAQLRSVDPATFHGLGRLHTLHLDRCGL 142
Query: 347 AELAPELFADLRALETFVMDGNELQ 371
EL P LF L AL+ + N LQ
Sbjct: 143 QELGPGLFRGLAALQYLYLQDNALQ 167
>AY899851-1|AAX85199.1| 730|Homo sapiens LGR8.1 protein.
Length = 730
Score = 76.2 bits (179), Expect = 2e-13
Identities = 56/200 (28%), Positives = 93/200 (46%), Gaps = 1/200 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L KI LPD F+ L+++ + N I +I+ AF GL N+ +L LN N I L
Sbjct: 142 LSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLR 201
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
G+F +L L + N + F GL+ + + + NN L + + + +P L
Sbjct: 202 PGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNW 261
Query: 292 LQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
+ L+ + I+ L F+S L L L+ N + L + + L L LS N + L
Sbjct: 262 VDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLH 321
Query: 351 PELFADLRALETFVMDGNEL 370
F L+ L++ ++ E+
Sbjct: 322 KNQFESLKQLQSLDLERIEI 341
Score = 74.5 bits (175), Expect = 6e-13
Identities = 45/157 (28%), Positives = 77/157 (49%), Gaps = 1/157 (0%)
Query: 215 HNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV 274
+NVT+LSL KN+I +LP +F +L + + N R++ + F GL ++Q + +++N
Sbjct: 137 NNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNC 196
Query: 275 PLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQ 333
TL+ +F +L L L LD + I + + F + L LS+ N L LP+ +
Sbjct: 197 ITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQM 256
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
QL + L N + L F +L + N +
Sbjct: 257 PQLNWVDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTI 293
Score = 65.7 bits (153), Expect = 3e-10
Identities = 46/155 (29%), Positives = 78/155 (50%), Gaps = 1/155 (0%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
L+ L L+ IT L F L+ L L + +N I I+ F GL+++ LS+ N ++
Sbjct: 187 LQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLE 246
Query: 229 ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPA 288
ALP + A P+L + + N +YL + TF D + + +S+N L +F +L
Sbjct: 247 ALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTITELSPHLFKDLKL 306
Query: 289 LRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQL 322
L+ L L + + L +F S L++L L R ++
Sbjct: 307 LQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEI 341
Score = 65.3 bits (152), Expect = 4e-10
Identities = 58/227 (25%), Positives = 97/227 (42%), Gaps = 5/227 (2%)
Query: 139 LRSLPKLTH----FRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLE 194
L+S+P +++ L + +L +F LK + L I + AF GL L+
Sbjct: 129 LKSVPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQ 188
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
L + N I + G F+ LH +T L L+ N I + LF L L+M+ N L
Sbjct: 189 ILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEAL 248
Query: 255 DSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLR 313
+ + + + + N L + F + +L L L ++I EL P F L+
Sbjct: 249 PKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTITELSPHLFKDLKLLQ 308
Query: 314 TLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 360
L+L+ N L L ++ QL SL L + + +F ++ L
Sbjct: 309 KLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNL 355
Score = 60.9 bits (141), Expect = 8e-09
Identities = 51/221 (23%), Positives = 87/221 (39%), Gaps = 1/221 (0%)
Query: 51 DCMGGELVCAEFPEIDTPA-TTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINP 109
DC EL C P + + LSL++ + L + + + K + N I
Sbjct: 116 DCKETELECVNGDLKSVPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRH 175
Query: 110 LNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPL 169
++ AF GL ++ N TT+ + + L +LT L+ + +F L
Sbjct: 176 ISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSL 235
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+L + + + LP + L +++ N I +T F ++TVL L+ N I
Sbjct: 236 FFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTITE 295
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKI 270
L LF L L + N YL F L +Q + +
Sbjct: 296 LSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDL 336
Score = 55.2 bits (127), Expect = 4e-07
Identities = 44/167 (26%), Positives = 73/167 (43%), Gaps = 2/167 (1%)
Query: 150 LNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAG 209
LN TL +F + L +L L D IT + F GLN L L++ N + +
Sbjct: 192 LNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQ 251
Query: 210 AFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIK 269
+ + + L NRI+ L F S L L + N+ L F+ L +Q++
Sbjct: 252 MCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTITELSPHLFKDLKLLQKLN 311
Query: 270 ISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLS 316
+S+N + L + F +L L++L L+ I + P++ LS
Sbjct: 312 LSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMF--QPMKNLS 356
Score = 42.7 bits (96), Expect = 0.002
Identities = 35/149 (23%), Positives = 58/149 (38%), Gaps = 2/149 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I ++ F GL + +P + +P+L L R L + F
Sbjct: 219 NPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFL 278
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
+ L L+LS IT L F L +L++LN+ N + + F L + L L +
Sbjct: 279 SCDSLTVLDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLER 338
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRY 253
I + +F L ++ +FRY
Sbjct: 339 IEIPNINTRMFQPMKNLSHIYF--KNFRY 365
>AY358297-1|AAQ88664.1| 473|Homo sapiens NOGOR protein.
Length = 473
Score = 76.2 bits (179), Expect = 2e-13
Identities = 52/172 (30%), Positives = 80/172 (46%), Gaps = 2/172 (1%)
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS-FRYLDSETF 259
N I+++ A +FR N+T+L L+ N + + A F L L + N+ R +D TF
Sbjct: 67 NRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATF 126
Query: 260 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLA 318
GL + + + L +F L AL+ L L ++++ LP++ F L L L
Sbjct: 127 HGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLH 186
Query: 319 RNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
N++ +P RG L L L N VA + P F DL L T + N L
Sbjct: 187 GNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNL 238
Score = 73.7 bits (173), Expect = 1e-12
Identities = 49/170 (28%), Positives = 81/170 (47%), Gaps = 1/170 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQT-TVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N + ++A AF GL + + + AQ +V L +L L+ L +F
Sbjct: 91 NVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLF 150
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
L+YL L D + LPDD F L L L + N I+++ AFRGLH++ L L+
Sbjct: 151 RGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLH 210
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
+NR+ + F RL+ L + N+ L +E L +Q +++++N
Sbjct: 211 QNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDN 260
Score = 67.7 bits (158), Expect = 7e-11
Identities = 54/187 (28%), Positives = 82/187 (43%), Gaps = 3/187 (1%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSD-AKITVLPDDAFLGLNV 192
VP R+ LT L++ + A F L+ L+LSD A++ + F GL
Sbjct: 72 VPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATFHGLGR 131
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
L L++ + + G FRGL + L L N +QALP F L +L + N
Sbjct: 132 LHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRIS 191
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPL 312
+ FRGL + + + N + F +L L TL L +++ LP E + +PL
Sbjct: 192 SVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEAL--APL 249
Query: 313 RTLSLAR 319
R L R
Sbjct: 250 RALQYLR 256
Score = 49.6 bits (113), Expect = 2e-05
Identities = 46/216 (21%), Positives = 84/216 (38%), Gaps = 1/216 (0%)
Query: 81 CSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLR 140
C L + + A + + N I+ + A +F+ ++ ++ +
Sbjct: 43 CPQQGLQAVPVGIPAASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFT 102
Query: 141 SLPKLTHFRLNAGRNI-TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
L L L+ + ++ F L L L + L F GL L+ L +
Sbjct: 103 GLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQ 162
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
+N + + FR L N+T L L+ NRI ++P F L L + +N ++ F
Sbjct: 163 DNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAF 222
Query: 260 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD 295
R L + + + N L + L AL+ L+L+
Sbjct: 223 RDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLN 258
Score = 35.9 bits (79), Expect = 0.25
Identities = 38/145 (26%), Positives = 63/145 (43%), Gaps = 25/145 (17%)
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
+QA+P G+ A++ R+ + N ++ + +FR ++ + + +NV + A F+ L
Sbjct: 48 LQAVPVGIPAASQRIF---LHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGL 104
Query: 287 PALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAV 346
L QLDLS QLR + + G +L +L L +
Sbjct: 105 ALLE--QLDLSD--------------------NAQLRSVDPATFHGLGRLHTLHLDRCGL 142
Query: 347 AELAPELFADLRALETFVMDGNELQ 371
EL P LF L AL+ + N LQ
Sbjct: 143 QELGPGLFRGLAALQYLYLQDNALQ 167
>AF283463-1|AAG53612.1| 473|Homo sapiens Nogo receptor protein.
Length = 473
Score = 76.2 bits (179), Expect = 2e-13
Identities = 52/172 (30%), Positives = 80/172 (46%), Gaps = 2/172 (1%)
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS-FRYLDSETF 259
N I+++ A +FR N+T+L L+ N + + A F L L + N+ R +D TF
Sbjct: 67 NRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATF 126
Query: 260 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLA 318
GL + + + L +F L AL+ L L ++++ LP++ F L L L
Sbjct: 127 HGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLH 186
Query: 319 RNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
N++ +P RG L L L N VA + P F DL L T + N L
Sbjct: 187 GNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNL 238
Score = 73.7 bits (173), Expect = 1e-12
Identities = 49/170 (28%), Positives = 81/170 (47%), Gaps = 1/170 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQT-TVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N + ++A AF GL + + + AQ +V L +L L+ L +F
Sbjct: 91 NVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLF 150
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
L+YL L D + LPDD F L L L + N I+++ AFRGLH++ L L+
Sbjct: 151 RGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLH 210
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
+NR+ + F RL+ L + N+ L +E L +Q +++++N
Sbjct: 211 QNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDN 260
Score = 67.7 bits (158), Expect = 7e-11
Identities = 54/187 (28%), Positives = 82/187 (43%), Gaps = 3/187 (1%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSD-AKITVLPDDAFLGLNV 192
VP R+ LT L++ + A F L+ L+LSD A++ + F GL
Sbjct: 72 VPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATFHGLGR 131
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
L L++ + + G FRGL + L L N +QALP F L +L + N
Sbjct: 132 LHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRIS 191
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPL 312
+ FRGL + + + N + F +L L TL L +++ LP E + +PL
Sbjct: 192 SVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEAL--APL 249
Query: 313 RTLSLAR 319
R L R
Sbjct: 250 RALQYLR 256
Score = 49.6 bits (113), Expect = 2e-05
Identities = 46/216 (21%), Positives = 84/216 (38%), Gaps = 1/216 (0%)
Query: 81 CSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLR 140
C L + + A + + N I+ + A +F+ ++ ++ +
Sbjct: 43 CPQQGLQAVPVGIPAASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFT 102
Query: 141 SLPKLTHFRLNAGRNI-TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
L L L+ + ++ F L L L + L F GL L+ L +
Sbjct: 103 GLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQ 162
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
+N + + FR L N+T L L+ NRI ++P F L L + +N ++ F
Sbjct: 163 DNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAF 222
Query: 260 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD 295
R L + + + N L + L AL+ L+L+
Sbjct: 223 RDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLN 258
Score = 35.9 bits (79), Expect = 0.25
Identities = 38/145 (26%), Positives = 63/145 (43%), Gaps = 25/145 (17%)
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
+QA+P G+ A++ R+ + N ++ + +FR ++ + + +NV + A F+ L
Sbjct: 48 LQAVPVGIPAASQRIF---LHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGL 104
Query: 287 PALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAV 346
L QLDLS QLR + + G +L +L L +
Sbjct: 105 ALLE--QLDLSD--------------------NAQLRSVDPATFHGLGRLHTLHLDRCGL 142
Query: 347 AELAPELFADLRALETFVMDGNELQ 371
EL P LF L AL+ + N LQ
Sbjct: 143 QELGPGLFRGLAALQYLYLQDNALQ 167
>Z93015-1|CAI42364.1| 481|Homo sapiens nyctalopin protein.
Length = 481
Score = 75.8 bits (178), Expect = 3e-13
Identities = 63/223 (28%), Positives = 101/223 (45%), Gaps = 3/223 (1%)
Query: 105 NAINPLNADAFKGLG-ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N ++ + AFKGL + L + + G + +L +L L A R ++ +
Sbjct: 96 NNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRLDLAACRLFSVPERLL 155
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
A P L+ L D +P A GL L ++ I + + + +GL + LSL
Sbjct: 156 AELPALRELAAFDNLFRRVPG-ALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQ 214
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
NR++A+ AG F L +L + N L ++ FRGL ++ + + N + A F
Sbjct: 215 ANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALDRVARAWF 274
Query: 284 SNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVL 325
++L L L LD +SI + E N S L L L N+L VL
Sbjct: 275 ADLAELELLYLDRNSIAFVEEGAFQNLSGLLALHLNGNRLTVL 317
Score = 72.9 bits (171), Expect = 2e-12
Identities = 60/210 (28%), Positives = 89/210 (42%), Gaps = 3/210 (1%)
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN-EIANITAGAFRGLHNVTVLS 221
F P L+ L L ++ + AF GL L +L + N ++ + A F L + L
Sbjct: 82 FGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRLD 141
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEA 281
L R+ ++P L A P L L N FR + RGL ++ + + +
Sbjct: 142 LAACRLFSVPERLLAELPALRELAAFDNLFRRVPG-ALRGLANLTHAHLERGRIEAVASS 200
Query: 282 VFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLT 340
L LR+L L + +R + F L L L N L LP RG +L +L
Sbjct: 201 SLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLN 260
Query: 341 LSYNAVAELAPELFADLRALETFVMDGNEL 370
L NA+ +A FADL LE +D N +
Sbjct: 261 LGGNALDRVARAWFADLAELELLYLDRNSI 290
Score = 68.9 bits (161), Expect = 3e-11
Identities = 47/162 (29%), Positives = 75/162 (46%), Gaps = 1/162 (0%)
Query: 210 AFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS-FRYLDSETFRGLDHIQEI 268
AF L ++ LSL N + + G F PRL L + N RYL + TF L ++ +
Sbjct: 81 AFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRL 140
Query: 269 KISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRS 328
++ ++ E + + LPALR L + R +P + L L R ++ + S
Sbjct: 141 DLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLANLTHAHLERGRIEAVASS 200
Query: 329 VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L+G +L SL+L N V + F D LE +++ N L
Sbjct: 201 SLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLL 242
Score = 58.0 bits (134), Expect = 5e-08
Identities = 55/201 (27%), Positives = 89/201 (44%), Gaps = 3/201 (1%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN-RIQAL 230
++L + L + AF L L +L++ N ++ IT GAF+GL + L L N ++ L
Sbjct: 67 IDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYL 126
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
A FA+ RL L + + L ++E+ +N+ + A+ L L
Sbjct: 127 HARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGAL-RGLANLT 185
Query: 291 TLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAEL 349
L+ I + + LR+LSL N++R + L L L+ N +AEL
Sbjct: 186 HAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAEL 245
Query: 350 APELFADLRALETFVMDGNEL 370
+ F LR L T + GN L
Sbjct: 246 PADAFRGLRRLRTLNLGGNAL 266
Score = 44.8 bits (101), Expect = 5e-04
Identities = 47/160 (29%), Positives = 62/160 (38%), Gaps = 24/160 (15%)
Query: 114 AFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLE 173
A +GL G V L+ L +L L A R +HA F + L++L
Sbjct: 177 ALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLL 236
Query: 174 LSDAKITVLPDDAFLGLNVLEQLNV-----------W-------------ENEIANITAG 209
L+D + LP DAF GL L LN+ W N IA + G
Sbjct: 237 LNDNLLAELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEG 296
Query: 210 AFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
AF+ L + L LN NR+ L F L L + RN
Sbjct: 297 AFQNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRN 336
Score = 33.1 bits (72), Expect = 1.8
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Query: 242 LNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL-DLSSIR 300
+++ + RN R+L F L ++ + + +N + F LP L L+L +R
Sbjct: 65 VSIDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLR 124
Query: 301 EL-PEEFISNSPLRTLSLARNQLRVLPRSVL 330
L F + S LR L LA +L +P +L
Sbjct: 125 YLHARTFAALSRLRRLDLAACRLFSVPERLL 155
>BC112242-1|AAI12243.1| 481|Homo sapiens nyctalopin protein.
Length = 481
Score = 75.8 bits (178), Expect = 3e-13
Identities = 63/223 (28%), Positives = 101/223 (45%), Gaps = 3/223 (1%)
Query: 105 NAINPLNADAFKGLG-ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N ++ + AFKGL + L + + G + +L +L L A R ++ +
Sbjct: 96 NNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRLDLAACRLFSVPERLL 155
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
A P L+ L D +P A GL L ++ I + + + +GL + LSL
Sbjct: 156 AELPALRELAAFDNLFRRVPG-ALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQ 214
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
NR++A+ AG F L +L + N L ++ FRGL ++ + + N + A F
Sbjct: 215 ANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALDRVARAWF 274
Query: 284 SNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVL 325
++L L L LD +SI + E N S L L L N+L VL
Sbjct: 275 ADLAELELLYLDRNSIAFVEEGAFQNLSGLLALHLNGNRLTVL 317
Score = 72.9 bits (171), Expect = 2e-12
Identities = 60/210 (28%), Positives = 89/210 (42%), Gaps = 3/210 (1%)
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN-EIANITAGAFRGLHNVTVLS 221
F P L+ L L ++ + AF GL L +L + N ++ + A F L + L
Sbjct: 82 FGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRLD 141
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEA 281
L R+ ++P L A P L L N FR + RGL ++ + + +
Sbjct: 142 LAACRLFSVPERLLAELPALRELAAFDNLFRRVPG-ALRGLANLTHAHLERGRIEAVASS 200
Query: 282 VFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLT 340
L LR+L L + +R + F L L L N L LP RG +L +L
Sbjct: 201 SLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLN 260
Query: 341 LSYNAVAELAPELFADLRALETFVMDGNEL 370
L NA+ +A FADL LE +D N +
Sbjct: 261 LGGNALDRVARAWFADLAELELLYLDRNSI 290
Score = 68.9 bits (161), Expect = 3e-11
Identities = 47/162 (29%), Positives = 75/162 (46%), Gaps = 1/162 (0%)
Query: 210 AFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS-FRYLDSETFRGLDHIQEI 268
AF L ++ LSL N + + G F PRL L + N RYL + TF L ++ +
Sbjct: 81 AFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRL 140
Query: 269 KISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRS 328
++ ++ E + + LPALR L + R +P + L L R ++ + S
Sbjct: 141 DLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLANLTHAHLERGRIEAVASS 200
Query: 329 VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L+G +L SL+L N V + F D LE +++ N L
Sbjct: 201 SLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLL 242
Score = 58.0 bits (134), Expect = 5e-08
Identities = 55/201 (27%), Positives = 89/201 (44%), Gaps = 3/201 (1%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN-RIQAL 230
++L + L + AF L L +L++ N ++ IT GAF+GL + L L N ++ L
Sbjct: 67 IDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYL 126
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
A FA+ RL L + + L ++E+ +N+ + A+ L L
Sbjct: 127 HARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGAL-RGLANLT 185
Query: 291 TLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAEL 349
L+ I + + LR+LSL N++R + L L L+ N +AEL
Sbjct: 186 HAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAEL 245
Query: 350 APELFADLRALETFVMDGNEL 370
+ F LR L T + GN L
Sbjct: 246 PADAFRGLRRLRTLNLGGNAL 266
Score = 44.8 bits (101), Expect = 5e-04
Identities = 47/160 (29%), Positives = 62/160 (38%), Gaps = 24/160 (15%)
Query: 114 AFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLE 173
A +GL G V L+ L +L L A R +HA F + L++L
Sbjct: 177 ALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLL 236
Query: 174 LSDAKITVLPDDAFLGLNVLEQLNV-----------W-------------ENEIANITAG 209
L+D + LP DAF GL L LN+ W N IA + G
Sbjct: 237 LNDNLLAELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEG 296
Query: 210 AFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
AF+ L + L LN NR+ L F L L + RN
Sbjct: 297 AFQNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRN 336
Score = 33.1 bits (72), Expect = 1.8
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Query: 242 LNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL-DLSSIR 300
+++ + RN R+L F L ++ + + +N + F LP L L+L +R
Sbjct: 65 VSIDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLR 124
Query: 301 EL-PEEFISNSPLRTLSLARNQLRVLPRSVL 330
L F + S LR L LA +L +P +L
Sbjct: 125 YLHARTFAALSRLRRLDLAACRLFSVPERLL 155
>AJ278865-1|CAC19014.1| 481|Homo sapiens leucine-rich repeat
protein protein.
Length = 481
Score = 75.8 bits (178), Expect = 3e-13
Identities = 63/223 (28%), Positives = 101/223 (45%), Gaps = 3/223 (1%)
Query: 105 NAINPLNADAFKGLG-ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N ++ + AFKGL + L + + G + +L +L L A R ++ +
Sbjct: 96 NNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRLDLAACRLFSVPERLL 155
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
A P L+ L D +P A GL L ++ I + + + +GL + LSL
Sbjct: 156 AELPALRELAAFDNLFRRVPG-ALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQ 214
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
NR++A+ AG F L +L + N L ++ FRGL ++ + + N + A F
Sbjct: 215 ANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALDRVARAWF 274
Query: 284 SNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVL 325
++L L L LD +SI + E N S L L L N+L VL
Sbjct: 275 ADLAELELLYLDRNSIAFVEEGAFQNLSGLLALHLNGNRLTVL 317
Score = 72.9 bits (171), Expect = 2e-12
Identities = 60/210 (28%), Positives = 89/210 (42%), Gaps = 3/210 (1%)
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN-EIANITAGAFRGLHNVTVLS 221
F P L+ L L ++ + AF GL L +L + N ++ + A F L + L
Sbjct: 82 FGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRLD 141
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEA 281
L R+ ++P L A P L L N FR + RGL ++ + + +
Sbjct: 142 LAACRLFSVPERLLAELPALRELAAFDNLFRRVPG-ALRGLANLTHAHLERGRIEAVASS 200
Query: 282 VFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLT 340
L LR+L L + +R + F L L L N L LP RG +L +L
Sbjct: 201 SLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLN 260
Query: 341 LSYNAVAELAPELFADLRALETFVMDGNEL 370
L NA+ +A FADL LE +D N +
Sbjct: 261 LGGNALDRVARAWFADLAELELLYLDRNSI 290
Score = 68.9 bits (161), Expect = 3e-11
Identities = 47/162 (29%), Positives = 75/162 (46%), Gaps = 1/162 (0%)
Query: 210 AFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS-FRYLDSETFRGLDHIQEI 268
AF L ++ LSL N + + G F PRL L + N RYL + TF L ++ +
Sbjct: 81 AFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRL 140
Query: 269 KISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRS 328
++ ++ E + + LPALR L + R +P + L L R ++ + S
Sbjct: 141 DLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLANLTHAHLERGRIEAVASS 200
Query: 329 VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L+G +L SL+L N V + F D LE +++ N L
Sbjct: 201 SLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLL 242
Score = 58.0 bits (134), Expect = 5e-08
Identities = 55/201 (27%), Positives = 89/201 (44%), Gaps = 3/201 (1%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN-RIQAL 230
++L + L + AF L L +L++ N ++ IT GAF+GL + L L N ++ L
Sbjct: 67 IDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYL 126
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
A FA+ RL L + + L ++E+ +N+ + A+ L L
Sbjct: 127 HARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGAL-RGLANLT 185
Query: 291 TLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAEL 349
L+ I + + LR+LSL N++R + L L L+ N +AEL
Sbjct: 186 HAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAEL 245
Query: 350 APELFADLRALETFVMDGNEL 370
+ F LR L T + GN L
Sbjct: 246 PADAFRGLRRLRTLNLGGNAL 266
Score = 44.8 bits (101), Expect = 5e-04
Identities = 47/160 (29%), Positives = 62/160 (38%), Gaps = 24/160 (15%)
Query: 114 AFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLE 173
A +GL G V L+ L +L L A R +HA F + L++L
Sbjct: 177 ALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLL 236
Query: 174 LSDAKITVLPDDAFLGLNVLEQLNV-----------W-------------ENEIANITAG 209
L+D + LP DAF GL L LN+ W N IA + G
Sbjct: 237 LNDNLLAELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEG 296
Query: 210 AFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
AF+ L + L LN NR+ L F L L + RN
Sbjct: 297 AFQNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRN 336
Score = 33.1 bits (72), Expect = 1.8
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Query: 242 LNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL-DLSSIR 300
+++ + RN R+L F L ++ + + +N + F LP L L+L +R
Sbjct: 65 VSIDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLR 124
Query: 301 EL-PEEFISNSPLRTLSLARNQLRVLPRSVL 330
L F + S LR L LA +L +P +L
Sbjct: 125 YLHARTFAALSRLRRLDLAACRLFSVPERLL 155
>AF254868-1|AAG42685.1| 481|Homo sapiens nyctalopin protein.
Length = 481
Score = 75.8 bits (178), Expect = 3e-13
Identities = 63/223 (28%), Positives = 101/223 (45%), Gaps = 3/223 (1%)
Query: 105 NAINPLNADAFKGLG-ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N ++ + AFKGL + L + + G + +L +L L A R ++ +
Sbjct: 96 NNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRLDLAACRLFSVPERLL 155
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
A P L+ L D +P A GL L ++ I + + + +GL + LSL
Sbjct: 156 AELPALRELAAFDNLFRRVPG-ALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQ 214
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
NR++A+ AG F L +L + N L ++ FRGL ++ + + N + A F
Sbjct: 215 ANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALDRVARAWF 274
Query: 284 SNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVL 325
++L L L LD +SI + E N S L L L N+L VL
Sbjct: 275 ADLAELELLYLDRNSIAFVEEGAFQNLSGLLALHLNGNRLTVL 317
Score = 72.9 bits (171), Expect = 2e-12
Identities = 60/210 (28%), Positives = 89/210 (42%), Gaps = 3/210 (1%)
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN-EIANITAGAFRGLHNVTVLS 221
F P L+ L L ++ + AF GL L +L + N ++ + A F L + L
Sbjct: 82 FGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRLD 141
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEA 281
L R+ ++P L A P L L N FR + RGL ++ + + +
Sbjct: 142 LAACRLFSVPERLLAELPALRELAAFDNLFRRVPG-ALRGLANLTHAHLERGRIEAVASS 200
Query: 282 VFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLT 340
L LR+L L + +R + F L L L N L LP RG +L +L
Sbjct: 201 SLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLN 260
Query: 341 LSYNAVAELAPELFADLRALETFVMDGNEL 370
L NA+ +A FADL LE +D N +
Sbjct: 261 LGGNALDRVARAWFADLAELELLYLDRNSI 290
Score = 68.9 bits (161), Expect = 3e-11
Identities = 47/162 (29%), Positives = 75/162 (46%), Gaps = 1/162 (0%)
Query: 210 AFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS-FRYLDSETFRGLDHIQEI 268
AF L ++ LSL N + + G F PRL L + N RYL + TF L ++ +
Sbjct: 81 AFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRL 140
Query: 269 KISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRS 328
++ ++ E + + LPALR L + R +P + L L R ++ + S
Sbjct: 141 DLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLANLTHAHLERGRIEAVASS 200
Query: 329 VLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L+G +L SL+L N V + F D LE +++ N L
Sbjct: 201 SLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLL 242
Score = 58.0 bits (134), Expect = 5e-08
Identities = 55/201 (27%), Positives = 89/201 (44%), Gaps = 3/201 (1%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN-RIQAL 230
++L + L + AF L L +L++ N ++ IT GAF+GL + L L N ++ L
Sbjct: 67 IDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYL 126
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
A FA+ RL L + + L ++E+ +N+ + A+ L L
Sbjct: 127 HARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGAL-RGLANLT 185
Query: 291 TLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAEL 349
L+ I + + LR+LSL N++R + L L L+ N +AEL
Sbjct: 186 HAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAEL 245
Query: 350 APELFADLRALETFVMDGNEL 370
+ F LR L T + GN L
Sbjct: 246 PADAFRGLRRLRTLNLGGNAL 266
Score = 44.8 bits (101), Expect = 5e-04
Identities = 47/160 (29%), Positives = 62/160 (38%), Gaps = 24/160 (15%)
Query: 114 AFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLE 173
A +GL G V L+ L +L L A R +HA F + L++L
Sbjct: 177 ALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLL 236
Query: 174 LSDAKITVLPDDAFLGLNVLEQLNV-----------W-------------ENEIANITAG 209
L+D + LP DAF GL L LN+ W N IA + G
Sbjct: 237 LNDNLLAELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEG 296
Query: 210 AFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
AF+ L + L LN NR+ L F L L + RN
Sbjct: 297 AFQNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRN 336
Score = 33.1 bits (72), Expect = 1.8
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Query: 242 LNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL-DLSSIR 300
+++ + RN R+L F L ++ + + +N + F LP L L+L +R
Sbjct: 65 VSIDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLR 124
Query: 301 EL-PEEFISNSPLRTLSLARNQLRVLPRSVL 330
L F + S LR L LA +L +P +L
Sbjct: 125 YLHARTFAALSRLRRLDLAACRLFSVPERLL 155
>BC041374-1|AAH41374.3| 640|Homo sapiens LRRC4C protein protein.
Length = 640
Score = 74.5 bits (175), Expect = 6e-13
Identities = 53/202 (26%), Positives = 89/202 (44%), Gaps = 2/202 (0%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+ L L + +I ++ ++F L LE L + N I I GAF GL N+ L L NR+
Sbjct: 79 RLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTT 138
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPA 288
+P G F +L L + N + S F + ++ + + L+ + E F L
Sbjct: 139 IPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSN 198
Query: 289 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
LR L L + ++RE+P L L L+ N L + +G L L + + +
Sbjct: 199 LRYLNLAMCNLREIP-NLTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQV 257
Query: 349 LAPELFADLRALETFVMDGNEL 370
+ F +L++L + N L
Sbjct: 258 IERNAFDNLQSLVEINLAHNNL 279
Score = 72.9 bits (171), Expect = 2e-12
Identities = 53/179 (29%), Positives = 89/179 (49%), Gaps = 4/179 (2%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
LN+ EN+I I +F+ L ++ +L L++N I+ + G F L L + N +
Sbjct: 81 LNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIP 140
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL-DLSSIRELPE-EFISNSPLR 313
+ F L ++E+ + NN ++ F+ +P+LR L L +L + + E F S LR
Sbjct: 141 NGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLR 200
Query: 314 TLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 372
L+LA LR +P L +L L LS N ++ + P F L L+ M +++QV
Sbjct: 201 YLNLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQV 257
Score = 62.9 bits (146), Expect = 2e-09
Identities = 55/226 (24%), Positives = 99/226 (43%), Gaps = 4/226 (1%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T L+ + + V+ + L L +L+ T+ F L LEL D ++T
Sbjct: 78 TRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLT 137
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK-NRIQALPAGLFASTP 239
+P+ AF+ L+ L++L + N I +I + AF + ++ L L + R+ + G F
Sbjct: 138 TIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLS 197
Query: 240 RLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI 299
L L + + R + + T L + E+ +S N ++ F L L+ L + S I
Sbjct: 198 NLRYLNLAMCNLREIPNLT--PLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQI 255
Query: 300 RELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
+ + N L ++LA N L +LP + L + L +N
Sbjct: 256 QVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
Score = 57.6 bits (133), Expect = 7e-08
Identities = 52/196 (26%), Positives = 88/196 (44%), Gaps = 11/196 (5%)
Query: 104 KNAINPLNADAFKGLG-ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANM 162
+N I + AF GL + L +F+ TT+P L KL L ++ +
Sbjct: 109 RNHIRTIEIGAFNGLANLNTLELFD-NRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYA 167
Query: 163 FANTPPLKYLELSDAK-ITVLPDDAFLGLNVLEQLNVWE---NEIANITAGAFRGLHNVT 218
F P L+ L+L + K ++ + + AF GL+ L LN+ EI N+T L +
Sbjct: 168 FNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTP-----LIKLD 222
Query: 219 VLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTL 278
L L+ N + A+ G F L L M+++ + ++ F L + EI +++N L
Sbjct: 223 ELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLL 282
Query: 279 KEAVFSNLPALRTLQL 294
+F+ L L + L
Sbjct: 283 PHDLFTPLHHLERIHL 298
Score = 52.4 bits (120), Expect = 3e-06
Identities = 36/173 (20%), Positives = 77/173 (44%), Gaps = 3/173 (1%)
Query: 102 VFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNIT-LHA 160
+F N + + AF L + ++P +P L L + ++ +
Sbjct: 131 LFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISE 190
Query: 161 NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVL 220
F L+YL L+ + +P+ L L++L++ N ++ I G+F+GL ++ L
Sbjct: 191 GAFEGLSNLRYLNLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKL 248
Query: 221 SLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
+ +++IQ + F + L+ + + N+ L + F L H++ I + +N
Sbjct: 249 WMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
Score = 52.0 bits (119), Expect = 4e-06
Identities = 42/157 (26%), Positives = 70/157 (44%), Gaps = 4/157 (2%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N +L+L++N+IQ + F L L + RN R ++ F GL ++ +++ +N
Sbjct: 77 NTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRL 136
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLAR-NQLRVLPRSVLRGQ 333
T+ F L L+ L L + I +P + P LR L L +L + G
Sbjct: 137 TTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGL 196
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ L L L+ + E+ P L L L+ + GN L
Sbjct: 197 SNLRYLNLAMCNLREI-PNL-TPLIKLDELDLSGNHL 231
>AY358293-1|AAQ88660.1| 640|Homo sapiens LNKM292 protein.
Length = 640
Score = 74.5 bits (175), Expect = 6e-13
Identities = 53/202 (26%), Positives = 89/202 (44%), Gaps = 2/202 (0%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+ L L + +I ++ ++F L LE L + N I I GAF GL N+ L L NR+
Sbjct: 79 RLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTT 138
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPA 288
+P G F +L L + N + S F + ++ + + L+ + E F L
Sbjct: 139 IPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSN 198
Query: 289 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
LR L L + ++RE+P L L L+ N L + +G L L + + +
Sbjct: 199 LRYLNLAMCNLREIP-NLTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQV 257
Query: 349 LAPELFADLRALETFVMDGNEL 370
+ F +L++L + N L
Sbjct: 258 IERNAFDNLQSLVEINLAHNNL 279
Score = 72.9 bits (171), Expect = 2e-12
Identities = 53/179 (29%), Positives = 89/179 (49%), Gaps = 4/179 (2%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
LN+ EN+I I +F+ L ++ +L L++N I+ + G F L L + N +
Sbjct: 81 LNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIP 140
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL-DLSSIRELPE-EFISNSPLR 313
+ F L ++E+ + NN ++ F+ +P+LR L L +L + + E F S LR
Sbjct: 141 NGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLR 200
Query: 314 TLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 372
L+LA LR +P L +L L LS N ++ + P F L L+ M +++QV
Sbjct: 201 YLNLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQV 257
Score = 62.9 bits (146), Expect = 2e-09
Identities = 55/226 (24%), Positives = 99/226 (43%), Gaps = 4/226 (1%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T L+ + + V+ + L L +L+ T+ F L LEL D ++T
Sbjct: 78 TRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLT 137
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK-NRIQALPAGLFASTP 239
+P+ AF+ L+ L++L + N I +I + AF + ++ L L + R+ + G F
Sbjct: 138 TIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLS 197
Query: 240 RLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI 299
L L + + R + + T L + E+ +S N ++ F L L+ L + S I
Sbjct: 198 NLRYLNLAMCNLREIPNLT--PLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQI 255
Query: 300 RELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
+ + N L ++LA N L +LP + L + L +N
Sbjct: 256 QVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
Score = 57.6 bits (133), Expect = 7e-08
Identities = 52/196 (26%), Positives = 88/196 (44%), Gaps = 11/196 (5%)
Query: 104 KNAINPLNADAFKGLG-ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANM 162
+N I + AF GL + L +F+ TT+P L KL L ++ +
Sbjct: 109 RNHIRTIEIGAFNGLANLNTLELFD-NRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYA 167
Query: 163 FANTPPLKYLELSDAK-ITVLPDDAFLGLNVLEQLNVWE---NEIANITAGAFRGLHNVT 218
F P L+ L+L + K ++ + + AF GL+ L LN+ EI N+T L +
Sbjct: 168 FNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTP-----LIKLD 222
Query: 219 VLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTL 278
L L+ N + A+ G F L L M+++ + ++ F L + EI +++N L
Sbjct: 223 ELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLL 282
Query: 279 KEAVFSNLPALRTLQL 294
+F+ L L + L
Sbjct: 283 PHDLFTPLHHLERIHL 298
Score = 52.4 bits (120), Expect = 3e-06
Identities = 36/173 (20%), Positives = 77/173 (44%), Gaps = 3/173 (1%)
Query: 102 VFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNIT-LHA 160
+F N + + AF L + ++P +P L L + ++ +
Sbjct: 131 LFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISE 190
Query: 161 NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVL 220
F L+YL L+ + +P+ L L++L++ N ++ I G+F+GL ++ L
Sbjct: 191 GAFEGLSNLRYLNLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKL 248
Query: 221 SLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
+ +++IQ + F + L+ + + N+ L + F L H++ I + +N
Sbjct: 249 WMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
Score = 52.0 bits (119), Expect = 4e-06
Identities = 42/157 (26%), Positives = 70/157 (44%), Gaps = 4/157 (2%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N +L+L++N+IQ + F L L + RN R ++ F GL ++ +++ +N
Sbjct: 77 NTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRL 136
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLAR-NQLRVLPRSVLRGQ 333
T+ F L L+ L L + I +P + P LR L L +L + G
Sbjct: 137 TTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGL 196
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ L L L+ + E+ P L L L+ + GN L
Sbjct: 197 SNLRYLNLAMCNLREI-PNL-TPLIKLDELDLSGNHL 231
>AB046800-1|BAB13406.1| 640|Homo sapiens KIAA1580 protein protein.
Length = 640
Score = 74.5 bits (175), Expect = 6e-13
Identities = 53/202 (26%), Positives = 89/202 (44%), Gaps = 2/202 (0%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+ L L + +I ++ ++F L LE L + N I I GAF GL N+ L L NR+
Sbjct: 79 RLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTT 138
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPA 288
+P G F +L L + N + S F + ++ + + L+ + E F L
Sbjct: 139 IPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSN 198
Query: 289 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
LR L L + ++RE+P L L L+ N L + +G L L + + +
Sbjct: 199 LRYLNLAMCNLREIP-NLTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQV 257
Query: 349 LAPELFADLRALETFVMDGNEL 370
+ F +L++L + N L
Sbjct: 258 IERNAFDNLQSLVEINLAHNNL 279
Score = 72.9 bits (171), Expect = 2e-12
Identities = 53/179 (29%), Positives = 89/179 (49%), Gaps = 4/179 (2%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
LN+ EN+I I +F+ L ++ +L L++N I+ + G F L L + N +
Sbjct: 81 LNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIP 140
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL-DLSSIRELPE-EFISNSPLR 313
+ F L ++E+ + NN ++ F+ +P+LR L L +L + + E F S LR
Sbjct: 141 NGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLR 200
Query: 314 TLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 372
L+LA LR +P L +L L LS N ++ + P F L L+ M +++QV
Sbjct: 201 YLNLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQV 257
Score = 62.9 bits (146), Expect = 2e-09
Identities = 55/226 (24%), Positives = 99/226 (43%), Gaps = 4/226 (1%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T L+ + + V+ + L L +L+ T+ F L LEL D ++T
Sbjct: 78 TRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLT 137
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK-NRIQALPAGLFASTP 239
+P+ AF+ L+ L++L + N I +I + AF + ++ L L + R+ + G F
Sbjct: 138 TIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLS 197
Query: 240 RLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI 299
L L + + R + + T L + E+ +S N ++ F L L+ L + S I
Sbjct: 198 NLRYLNLAMCNLREIPNLT--PLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQI 255
Query: 300 RELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
+ + N L ++LA N L +LP + L + L +N
Sbjct: 256 QVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
Score = 57.6 bits (133), Expect = 7e-08
Identities = 52/196 (26%), Positives = 88/196 (44%), Gaps = 11/196 (5%)
Query: 104 KNAINPLNADAFKGLG-ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANM 162
+N I + AF GL + L +F+ TT+P L KL L ++ +
Sbjct: 109 RNHIRTIEIGAFNGLANLNTLELFD-NRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYA 167
Query: 163 FANTPPLKYLELSDAK-ITVLPDDAFLGLNVLEQLNVWE---NEIANITAGAFRGLHNVT 218
F P L+ L+L + K ++ + + AF GL+ L LN+ EI N+T L +
Sbjct: 168 FNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTP-----LIKLD 222
Query: 219 VLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTL 278
L L+ N + A+ G F L L M+++ + ++ F L + EI +++N L
Sbjct: 223 ELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLL 282
Query: 279 KEAVFSNLPALRTLQL 294
+F+ L L + L
Sbjct: 283 PHDLFTPLHHLERIHL 298
Score = 52.4 bits (120), Expect = 3e-06
Identities = 36/173 (20%), Positives = 77/173 (44%), Gaps = 3/173 (1%)
Query: 102 VFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNIT-LHA 160
+F N + + AF L + ++P +P L L + ++ +
Sbjct: 131 LFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISE 190
Query: 161 NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVL 220
F L+YL L+ + +P+ L L++L++ N ++ I G+F+GL ++ L
Sbjct: 191 GAFEGLSNLRYLNLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKL 248
Query: 221 SLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
+ +++IQ + F + L+ + + N+ L + F L H++ I + +N
Sbjct: 249 WMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
Score = 52.0 bits (119), Expect = 4e-06
Identities = 42/157 (26%), Positives = 70/157 (44%), Gaps = 4/157 (2%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N +L+L++N+IQ + F L L + RN R ++ F GL ++ +++ +N
Sbjct: 77 NTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRL 136
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLAR-NQLRVLPRSVLRGQ 333
T+ F L L+ L L + I +P + P LR L L +L + G
Sbjct: 137 TTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGL 196
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ L L L+ + E+ P L L L+ + GN L
Sbjct: 197 SNLRYLNLAMCNLREI-PNL-TPLIKLDELDLSGNHL 231
>BC045113-1|AAH45113.1| 522|Homo sapiens LRRTM1 protein protein.
Length = 522
Score = 74.1 bits (174), Expect = 8e-13
Identities = 50/184 (27%), Positives = 91/184 (49%), Gaps = 1/184 (0%)
Query: 190 LNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
L+ L L++ N ++ + AG F GL +T L L+ N I ++ F R+ LT+ N
Sbjct: 64 LSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSN 123
Query: 250 SFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN 309
L + TFR + +++ + +S N L +F L L TL + ++I+ +P +
Sbjct: 124 QITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQD 183
Query: 310 -SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
L+ L + NQL+ L R+ G +LT L L +N + ++ F L +L + + N
Sbjct: 184 CRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRN 243
Query: 369 ELQV 372
++ +
Sbjct: 244 KVAI 247
Score = 73.7 bits (173), Expect = 1e-12
Identities = 54/227 (23%), Positives = 99/227 (43%)
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
L +LT L+ ++ + F +K L LS +IT LP+ F + L +++ N
Sbjct: 88 LMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYN 147
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG 261
++ + F GL +T L + N IQ +P +F L L + N + L +F G
Sbjct: 148 KLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAG 207
Query: 262 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 321
L + E+ + +N + + A F L +L +L L + + + L + L+ N+
Sbjct: 208 LFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSSLDWVWNLEKMDLSGNE 267
Query: 322 LRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
+ + V L SL L N + + P + ++L + + GN
Sbjct: 268 IEYMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGN 314
Score = 71.7 bits (168), Expect = 4e-12
Identities = 55/214 (25%), Positives = 98/214 (45%), Gaps = 2/214 (0%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L A F L +L L I + DAF L +++L + N+I + FR + N+
Sbjct: 80 LRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNL 139
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
+ L+ N++QAL LF +L L M N+ +++ F+ ++ + I N +
Sbjct: 140 RSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKS 199
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
L F+ L L L L+ + + ++ F L +L L RN++ ++ S L L
Sbjct: 200 LARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSS-LDWVWNL 258
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ LS N + + P +F + L++ +D N L
Sbjct: 259 EKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRL 292
Score = 59.7 bits (138), Expect = 2e-08
Identities = 62/271 (22%), Positives = 114/271 (42%), Gaps = 3/271 (1%)
Query: 52 CMGGELVCAEFPEIDTPATTQ-LPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPL 110
C G L C + P L LSLR SL L + + N I +
Sbjct: 45 CEGRLLYCEALNLTEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSV 104
Query: 111 NADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLK 170
DAF+ L + ++ T +P R +P L L+ + L ++F L
Sbjct: 105 QGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLT 164
Query: 171 YLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
L + I +P F L+ L++ N++ ++ +F GL +T L L N + +
Sbjct: 165 TLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKV 224
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
F L +L + RN + S + + +++++ +S N ++ VF +P L+
Sbjct: 225 NFAHFPRLISLHSLCLRRNKVAIVVS-SLDWVWNLEKMDLSGNEIEYMEPHVFETVPHLQ 283
Query: 291 TLQLDLSSIRELPEEFISN-SPLRTLSLARN 320
+LQLD + + + +++ L +++LA N
Sbjct: 284 SLQLDSNRLTYIEPRILNSWKSLTSITLAGN 314
Score = 58.0 bits (134), Expect = 5e-08
Identities = 54/208 (25%), Positives = 87/208 (41%), Gaps = 2/208 (0%)
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N L L L ++ L F GL L L + N I ++ AF+ L V L+L+
Sbjct: 63 NLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSS 122
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N+I LP F P L ++ + N + L + F GL + + + N + +F
Sbjct: 123 NQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQ 182
Query: 285 NLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+ +L+ L + + ++ L F L L L N L + + L SL L
Sbjct: 183 DCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRR 242
Query: 344 NAVAELAPELFADLRALETFVMDGNELQ 371
N VA + L + LE + GNE++
Sbjct: 243 NKVAIVVSSL-DWVWNLEKMDLSGNEIE 269
Score = 45.6 bits (103), Expect = 3e-04
Identities = 38/170 (22%), Positives = 67/170 (39%), Gaps = 1/170 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L D F GL + A A VPV + + L + + +L N FA
Sbjct: 147 NKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFA 206
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L L L + + F L L L + N++A I + + N+ + L+
Sbjct: 207 GLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVA-IVVSSLDWVWNLEKMDLSG 265
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV 274
N I+ + +F + P L +L + N Y++ + I ++ N+
Sbjct: 266 NEIEYMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGNL 315
>AY899849-1|AAX85197.1| 709|Homo sapiens LGR7.2 protein.
Length = 709
Score = 74.1 bits (174), Expect = 8e-13
Identities = 55/184 (29%), Positives = 90/184 (48%), Gaps = 2/184 (1%)
Query: 179 ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFAST 238
I LP D F + L++L + N+I +I+ AFRGL+++T L L+ NRI L G+F
Sbjct: 138 IRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDL 197
Query: 239 PRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKE-AVFSNLPALRTLQLDLS 297
RL L + N + TF GL+ + + + NNV L + + ++P L L L+ +
Sbjct: 198 HRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGN 257
Query: 298 SIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFAD 356
I L FIS S L L + +N++ L + +L +L ++ + +F
Sbjct: 258 HIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDEFSLEGIEISNIQQRMFRP 317
Query: 357 LRAL 360
L L
Sbjct: 318 LMNL 321
Score = 54.8 bits (126), Expect = 5e-07
Identities = 45/157 (28%), Positives = 70/157 (44%), Gaps = 2/157 (1%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
NVT +SL N I+ LP F + L L + N + FRGL+ + ++ +S+N
Sbjct: 127 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 186
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLP-RSVLRGQ 333
LK VF +L L L ++ + + + P F + L L L N L LP + + +
Sbjct: 187 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 246
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+L L L N + L F L VM N++
Sbjct: 247 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKI 283
Score = 50.0 bits (114), Expect = 1e-05
Identities = 48/184 (26%), Positives = 76/184 (41%), Gaps = 3/184 (1%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
+P D ++ L L + ++ F L L LS +IT L F L+ L
Sbjct: 141 LPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRL 200
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP-AGLFASTPRLLNLTMMRNSFR 252
E L + +N ++ I+ F GL+++ +L L N + LP L PRL L + N
Sbjct: 201 EWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIH 260
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPL 312
L + TF ++ + + N L E F+ L L L+ I + + PL
Sbjct: 261 NLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDEFSLEGIEISNIQQRMF--RPL 318
Query: 313 RTLS 316
LS
Sbjct: 319 MNLS 322
Score = 44.8 bits (101), Expect = 5e-04
Identities = 56/242 (23%), Positives = 94/242 (38%), Gaps = 5/242 (2%)
Query: 29 YQCSRPSTNLIVGARPRDYVNIDCMGGELVCAEFPEIDTPA-TTQLPSLSLRECSLPPLS 87
Y + +VG+ P V C G EL C E P+ ++ + ++SL+ + L
Sbjct: 86 YPFEAETPECLVGSVP---VQCLCQGLELDCDETNLRAVPSVSSNVTAMSLQWNLIRKLP 142
Query: 88 CLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTH 147
K + + K + N I ++ AF+GL + + T + V L +L
Sbjct: 143 PDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEW 202
Query: 148 FRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLG-LNVLEQLNVWENEIANI 206
+ + F L L L + +T LPD + L L++ N I N+
Sbjct: 203 LIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNL 262
Query: 207 TAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQ 266
F N+TVL + KN+I L FA +L ++ + FR L ++
Sbjct: 263 RNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDEFSLEGIEISNIQQRMFRPLMNLS 322
Query: 267 EI 268
I
Sbjct: 323 HI 324
>AY358310-1|AAQ88677.1| 522|Homo sapiens DFLL675 protein.
Length = 522
Score = 74.1 bits (174), Expect = 8e-13
Identities = 50/184 (27%), Positives = 91/184 (49%), Gaps = 1/184 (0%)
Query: 190 LNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
L+ L L++ N ++ + AG F GL +T L L+ N I ++ F R+ LT+ N
Sbjct: 64 LSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSN 123
Query: 250 SFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN 309
L + TFR + +++ + +S N L +F L L TL + ++I+ +P +
Sbjct: 124 QITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQD 183
Query: 310 -SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
L+ L + NQL+ L R+ G +LT L L +N + ++ F L +L + + N
Sbjct: 184 CRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRN 243
Query: 369 ELQV 372
++ +
Sbjct: 244 KVAI 247
Score = 73.7 bits (173), Expect = 1e-12
Identities = 54/227 (23%), Positives = 99/227 (43%)
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
L +LT L+ ++ + F +K L LS +IT LP+ F + L +++ N
Sbjct: 88 LMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYN 147
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG 261
++ + F GL +T L + N IQ +P +F L L + N + L +F G
Sbjct: 148 KLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAG 207
Query: 262 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 321
L + E+ + +N + + A F L +L +L L + + + L + L+ N+
Sbjct: 208 LFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSSLDWVWNLEKMDLSGNE 267
Query: 322 LRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
+ + V L SL L N + + P + ++L + + GN
Sbjct: 268 IEYMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGN 314
Score = 71.7 bits (168), Expect = 4e-12
Identities = 55/214 (25%), Positives = 98/214 (45%), Gaps = 2/214 (0%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L A F L +L L I + DAF L +++L + N+I + FR + N+
Sbjct: 80 LRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNL 139
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
+ L+ N++QAL LF +L L M N+ +++ F+ ++ + I N +
Sbjct: 140 RSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKS 199
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
L F+ L L L L+ + + ++ F L +L L RN++ ++ S L L
Sbjct: 200 LARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSS-LDWVWNL 258
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ LS N + + P +F + L++ +D N L
Sbjct: 259 EKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRL 292
Score = 59.7 bits (138), Expect = 2e-08
Identities = 62/271 (22%), Positives = 114/271 (42%), Gaps = 3/271 (1%)
Query: 52 CMGGELVCAEFPEIDTPATTQ-LPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPL 110
C G L C + P L LSLR SL L + + N I +
Sbjct: 45 CEGRLLYCEALNLTEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSV 104
Query: 111 NADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLK 170
DAF+ L + ++ T +P R +P L L+ + L ++F L
Sbjct: 105 QGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLT 164
Query: 171 YLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
L + I +P F L+ L++ N++ ++ +F GL +T L L N + +
Sbjct: 165 TLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKV 224
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
F L +L + RN + S + + +++++ +S N ++ VF +P L+
Sbjct: 225 NFAHFPRLISLHSLCLRRNKVAIVVS-SLDWVWNLEKMDLSGNEIEYMEPHVFETVPHLQ 283
Query: 291 TLQLDLSSIRELPEEFISN-SPLRTLSLARN 320
+LQLD + + + +++ L +++LA N
Sbjct: 284 SLQLDSNRLTYIEPRILNSWKSLTSITLAGN 314
Score = 58.0 bits (134), Expect = 5e-08
Identities = 54/208 (25%), Positives = 87/208 (41%), Gaps = 2/208 (0%)
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N L L L ++ L F GL L L + N I ++ AF+ L V L+L+
Sbjct: 63 NLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSS 122
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N+I LP F P L ++ + N + L + F GL + + + N + +F
Sbjct: 123 NQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQ 182
Query: 285 NLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+ +L+ L + + ++ L F L L L N L + + L SL L
Sbjct: 183 DCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRR 242
Query: 344 NAVAELAPELFADLRALETFVMDGNELQ 371
N VA + L + LE + GNE++
Sbjct: 243 NKVAIVVSSL-DWVWNLEKMDLSGNEIE 269
Score = 45.6 bits (103), Expect = 3e-04
Identities = 38/170 (22%), Positives = 67/170 (39%), Gaps = 1/170 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L D F GL + A A VPV + + L + + +L N FA
Sbjct: 147 NKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFA 206
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L L L + + F L L L + N++A I + + N+ + L+
Sbjct: 207 GLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVA-IVVSSLDWVWNLEKMDLSG 265
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV 274
N I+ + +F + P L +L + N Y++ + I ++ N+
Sbjct: 266 NEIEYMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGNL 315
>AY182024-1|AAO67545.1| 522|Homo sapiens leucine-rich repeat
transmembrane neuronal 1 protein protein.
Length = 522
Score = 74.1 bits (174), Expect = 8e-13
Identities = 50/184 (27%), Positives = 91/184 (49%), Gaps = 1/184 (0%)
Query: 190 LNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
L+ L L++ N ++ + AG F GL +T L L+ N I ++ F R+ LT+ N
Sbjct: 64 LSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSN 123
Query: 250 SFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN 309
L + TFR + +++ + +S N L +F L L TL + ++I+ +P +
Sbjct: 124 QITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQD 183
Query: 310 -SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
L+ L + NQL+ L R+ G +LT L L +N + ++ F L +L + + N
Sbjct: 184 CRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRN 243
Query: 369 ELQV 372
++ +
Sbjct: 244 KVAI 247
Score = 73.7 bits (173), Expect = 1e-12
Identities = 54/227 (23%), Positives = 99/227 (43%)
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
L +LT L+ ++ + F +K L LS +IT LP+ F + L +++ N
Sbjct: 88 LMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYN 147
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG 261
++ + F GL +T L + N IQ +P +F L L + N + L +F G
Sbjct: 148 KLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAG 207
Query: 262 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 321
L + E+ + +N + + A F L +L +L L + + + L + L+ N+
Sbjct: 208 LFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSSLDWVWNLEKMDLSGNE 267
Query: 322 LRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
+ + V L SL L N + + P + ++L + + GN
Sbjct: 268 IEYMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGN 314
Score = 71.7 bits (168), Expect = 4e-12
Identities = 55/214 (25%), Positives = 98/214 (45%), Gaps = 2/214 (0%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L A F L +L L I + DAF L +++L + N+I + FR + N+
Sbjct: 80 LRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNL 139
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
+ L+ N++QAL LF +L L M N+ +++ F+ ++ + I N +
Sbjct: 140 RSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKS 199
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
L F+ L L L L+ + + ++ F L +L L RN++ ++ S L L
Sbjct: 200 LARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSS-LDWVWNL 258
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ LS N + + P +F + L++ +D N L
Sbjct: 259 EKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRL 292
Score = 59.7 bits (138), Expect = 2e-08
Identities = 62/271 (22%), Positives = 114/271 (42%), Gaps = 3/271 (1%)
Query: 52 CMGGELVCAEFPEIDTPATTQ-LPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPL 110
C G L C + P L LSLR SL L + + N I +
Sbjct: 45 CEGRLLYCEALNLTEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSV 104
Query: 111 NADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLK 170
DAF+ L + ++ T +P R +P L L+ + L ++F L
Sbjct: 105 QGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLT 164
Query: 171 YLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
L + I +P F L+ L++ N++ ++ +F GL +T L L N + +
Sbjct: 165 TLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKV 224
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
F L +L + RN + S + + +++++ +S N ++ VF +P L+
Sbjct: 225 NFAHFPRLISLHSLCLRRNKVAIVVS-SLDWVWNLEKMDLSGNEIEYMEPHVFETVPHLQ 283
Query: 291 TLQLDLSSIRELPEEFISN-SPLRTLSLARN 320
+LQLD + + + +++ L +++LA N
Sbjct: 284 SLQLDSNRLTYIEPRILNSWKSLTSITLAGN 314
Score = 58.0 bits (134), Expect = 5e-08
Identities = 54/208 (25%), Positives = 87/208 (41%), Gaps = 2/208 (0%)
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N L L L ++ L F GL L L + N I ++ AF+ L V L+L+
Sbjct: 63 NLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSS 122
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N+I LP F P L ++ + N + L + F GL + + + N + +F
Sbjct: 123 NQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQ 182
Query: 285 NLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+ +L+ L + + ++ L F L L L N L + + L SL L
Sbjct: 183 DCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRR 242
Query: 344 NAVAELAPELFADLRALETFVMDGNELQ 371
N VA + L + LE + GNE++
Sbjct: 243 NKVAIVVSSL-DWVWNLEKMDLSGNEIE 269
Score = 45.6 bits (103), Expect = 3e-04
Identities = 38/170 (22%), Positives = 67/170 (39%), Gaps = 1/170 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L D F GL + A A VPV + + L + + +L N FA
Sbjct: 147 NKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFA 206
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L L L + + F L L L + N++A I + + N+ + L+
Sbjct: 207 GLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVA-IVVSSLDWVWNLEKMDLSG 265
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV 274
N I+ + +F + P L +L + N Y++ + I ++ N+
Sbjct: 266 NEIEYMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGNL 315
>AL356953-5|CAI15931.1| 232|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 232
Score = 74.1 bits (174), Expect = 8e-13
Identities = 52/199 (26%), Positives = 90/199 (45%), Gaps = 2/199 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ + AF GL ++M +P + L LP L RL+A + F
Sbjct: 26 NHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFE 85
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L++L L D +T +P A L L+ + + N I++I AF+ L ++ VL LN
Sbjct: 86 GLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLDLNY 145
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N++Q P + + RL L+ + + + +G ++ + ++ L +
Sbjct: 146 NKLQEFPVAI-RTLGRLQELS-LNGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQ 203
Query: 285 NLPALRTLQLDLSSIRELP 303
LP LR L+L + I ELP
Sbjct: 204 QLPRLRVLELSHNQIEELP 222
Score = 73.3 bits (172), Expect = 1e-12
Identities = 46/165 (27%), Positives = 83/165 (50%), Gaps = 2/165 (1%)
Query: 179 ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFAST 238
+T L F L LE+L + N +++I AF GL+++ +L L N++ +PA
Sbjct: 4 LTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWEL 63
Query: 239 PRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSS 298
P L +L + N + +F GL ++ + + +N + +NLPAL+ + L L+
Sbjct: 64 PSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNR 123
Query: 299 IRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS 342
I +P+ N + L L L N+L+ P ++ R +L L+L+
Sbjct: 124 ISHIPDYAFQNLTSLVVLDLNYNKLQEFPVAI-RTLGRLQELSLN 167
Score = 68.1 bits (159), Expect = 5e-11
Identities = 44/168 (26%), Positives = 79/168 (47%), Gaps = 2/168 (1%)
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
N + + G F L + L L+ N + +P F+ L L + N + +E
Sbjct: 2 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 61
Query: 261 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLAR 319
L +Q +++ N+ + E F L +LR L LD +++ E+P ++N P L+ ++LA
Sbjct: 62 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL 121
Query: 320 NQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 367
N++ +P + T L L L+YN + E P L L+ ++G
Sbjct: 122 NRISHIPDYAFQNLTSLVVLDLNYNKLQEF-PVAIRTLGRLQELSLNG 168
Score = 65.3 bits (152), Expect = 4e-10
Identities = 55/218 (25%), Positives = 97/218 (44%), Gaps = 2/218 (0%)
Query: 155 NIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRG 213
N+T L +F + L+ L LS ++ +P AF GL L+ L + N++ I A A
Sbjct: 3 NLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWE 62
Query: 214 LHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L ++ L L+ N I +P F L +L + N+ + L +Q + ++ N
Sbjct: 63 LPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALN 122
Query: 274 VPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQ 333
+ + F NL +L L L+ + ++E P + L+ LSL + + L+G
Sbjct: 123 RISHIPDYAFQNLTSLVVLDLNYNKLQEFPVAIRTLGRLQELSL-NGAMDIQEFPDLKGT 181
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
T L LTL+ + L + L L + N+++
Sbjct: 182 TSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIE 219
Score = 62.5 bits (145), Expect = 3e-09
Identities = 51/206 (24%), Positives = 93/206 (45%), Gaps = 3/206 (1%)
Query: 145 LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIA 204
L RL+ + F+ LK L L + ++ +P +A L L+ L + N I+
Sbjct: 18 LEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLIS 77
Query: 205 NITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDH 264
+ +F GL ++ L L+ N + +P + P L +T+ N ++ F+ L
Sbjct: 78 LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTS 137
Query: 265 IQEIKISNNVPLTLKEAVFSNLPALRTLQLD-LSSIRELPEEFISNSPLRTLSLARNQLR 323
+ + ++ N A+ L L+ L L+ I+E P+ + L L+L R +R
Sbjct: 138 LVVLDLNYNKLQEFPVAI-RTLGRLQELSLNGAMDIQEFPD-LKGTTSLEILTLTRAGIR 195
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAEL 349
+LP + + +L L LS+N + EL
Sbjct: 196 LLPSGMCQQLPRLRVLELSHNQIEEL 221
Score = 56.8 bits (131), Expect = 1e-07
Identities = 53/223 (23%), Positives = 89/223 (39%), Gaps = 3/223 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L F L + + + +P L L L + + A
Sbjct: 2 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 61
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
P L+ L L I+++P+ +F GL+ L L + +N + I A L + ++L
Sbjct: 62 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL 121
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
NRI +P F + L+ L + N + R L +QE+ ++ + + +
Sbjct: 122 NRISHIPDYAFQNLTSLVVLDLNYNKLQEF-PVAIRTLGRLQELSLNGAMDIQ-EFPDLK 179
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLP 326
+L L L + IR LP P LR L L+ NQ+ LP
Sbjct: 180 GTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELP 222
Score = 47.2 bits (107), Expect = 1e-04
Identities = 42/153 (27%), Positives = 69/153 (45%), Gaps = 4/153 (2%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I+ + +F+GL + + A T +PV L +LP L L R + F
Sbjct: 74 NLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQ 133
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGA-FRGLHNVTVLSLN 223
N L L+L+ K+ P A L L++L++ N +I +G ++ +L+L
Sbjct: 134 NLTSLVVLDLNYNKLQEFPV-AIRTLGRLQELSL--NGAMDIQEFPDLKGTTSLEILTLT 190
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDS 256
+ I+ LP+G+ PRL L + N L S
Sbjct: 191 RAGIRLLPSGMCQQLPRLRVLELSHNQIEELPS 223
>AK056644-1|BAB71240.1| 522|Homo sapiens protein ( Homo sapiens
cDNA FLJ32082 fis, clone OCBBF2000231, weakly similar to
PHOSPHOLIPASE A2 INHIBITOR SUBUNIT B PRECURSOR. ).
Length = 522
Score = 74.1 bits (174), Expect = 8e-13
Identities = 50/184 (27%), Positives = 91/184 (49%), Gaps = 1/184 (0%)
Query: 190 LNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
L+ L L++ N ++ + AG F GL +T L L+ N I ++ F R+ LT+ N
Sbjct: 64 LSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSN 123
Query: 250 SFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN 309
L + TFR + +++ + +S N L +F L L TL + ++I+ +P +
Sbjct: 124 QITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQD 183
Query: 310 -SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
L+ L + NQL+ L R+ G +LT L L +N + ++ F L +L + + N
Sbjct: 184 CRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRN 243
Query: 369 ELQV 372
++ +
Sbjct: 244 KVAI 247
Score = 73.7 bits (173), Expect = 1e-12
Identities = 54/227 (23%), Positives = 99/227 (43%)
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
L +LT L+ ++ + F +K L LS +IT LP+ F + L +++ N
Sbjct: 88 LMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYN 147
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG 261
++ + F GL +T L + N IQ +P +F L L + N + L +F G
Sbjct: 148 KLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAG 207
Query: 262 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQ 321
L + E+ + +N + + A F L +L +L L + + + L + L+ N+
Sbjct: 208 LFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSSLDWVWNLEKMDLSGNE 267
Query: 322 LRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
+ + V L SL L N + + P + ++L + + GN
Sbjct: 268 IEYMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGN 314
Score = 71.7 bits (168), Expect = 4e-12
Identities = 55/214 (25%), Positives = 98/214 (45%), Gaps = 2/214 (0%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L A F L +L L I + DAF L +++L + N+I + FR + N+
Sbjct: 80 LRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNL 139
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
+ L+ N++QAL LF +L L M N+ +++ F+ ++ + I N +
Sbjct: 140 RSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKS 199
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
L F+ L L L L+ + + ++ F L +L L RN++ ++ S L L
Sbjct: 200 LARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSS-LDWVWNL 258
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ LS N + + P +F + L++ +D N L
Sbjct: 259 EKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRL 292
Score = 59.7 bits (138), Expect = 2e-08
Identities = 62/271 (22%), Positives = 114/271 (42%), Gaps = 3/271 (1%)
Query: 52 CMGGELVCAEFPEIDTPATTQ-LPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPL 110
C G L C + P L LSLR SL L + + N I +
Sbjct: 45 CEGRLLYCEALNLTEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSV 104
Query: 111 NADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLK 170
DAF+ L + ++ T +P R +P L L+ + L ++F L
Sbjct: 105 QGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLT 164
Query: 171 YLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
L + I +P F L+ L++ N++ ++ +F GL +T L L N + +
Sbjct: 165 TLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKV 224
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
F L +L + RN + S + + +++++ +S N ++ VF +P L+
Sbjct: 225 NFAHFPRLISLHSLCLRRNKVAIVVS-SLDWVWNLEKMDLSGNEIEYMEPHVFETVPHLQ 283
Query: 291 TLQLDLSSIRELPEEFISN-SPLRTLSLARN 320
+LQLD + + + +++ L +++LA N
Sbjct: 284 SLQLDSNRLTYIEPRILNSWKSLTSITLAGN 314
Score = 58.0 bits (134), Expect = 5e-08
Identities = 54/208 (25%), Positives = 87/208 (41%), Gaps = 2/208 (0%)
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N L L L ++ L F GL L L + N I ++ AF+ L V L+L+
Sbjct: 63 NLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSS 122
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N+I LP F P L ++ + N + L + F GL + + + N + +F
Sbjct: 123 NQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQ 182
Query: 285 NLPALRTLQLDLSSIRELP-EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+ +L+ L + + ++ L F L L L N L + + L SL L
Sbjct: 183 DCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRR 242
Query: 344 NAVAELAPELFADLRALETFVMDGNELQ 371
N VA + L + LE + GNE++
Sbjct: 243 NKVAIVVSSL-DWVWNLEKMDLSGNEIE 269
Score = 45.6 bits (103), Expect = 3e-04
Identities = 38/170 (22%), Positives = 67/170 (39%), Gaps = 1/170 (0%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + L D F GL + A A VPV + + L + + +L N FA
Sbjct: 147 NKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFA 206
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L L L + + F L L L + N++A I + + N+ + L+
Sbjct: 207 GLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVA-IVVSSLDWVWNLEKMDLSG 265
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV 274
N I+ + +F + P L +L + N Y++ + I ++ N+
Sbjct: 266 NEIEYMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGNL 315
>AL512424-2|CAI14256.1| 380|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 380
Score = 73.7 bits (173), Expect = 1e-12
Identities = 40/123 (32%), Positives = 66/123 (53%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
LEL+ IT + + F GL L L + EN+I + GAF + + L L++N IQA+P
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENAIQAIP 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
F L NL + +N ++ FR L ++ + ++NN T+ + F+++P LRT
Sbjct: 126 RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRT 185
Query: 292 LQL 294
+L
Sbjct: 186 FRL 188
Score = 64.5 bits (150), Expect = 6e-10
Identities = 42/136 (30%), Positives = 72/136 (52%), Gaps = 3/136 (2%)
Query: 140 RSLPKLTH-FRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
+++P+ T LN G NIT +H N FA L+ L+L + +I + AF + LE+L+
Sbjct: 57 KNIPRNTERLELN-GNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLD 115
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSE 257
+ EN I I AFRG ++ L L+KN+I + G F + L LT+ N+ +
Sbjct: 116 LSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVS 175
Query: 258 TFRGLDHIQEIKISNN 273
+F + ++ ++ +N
Sbjct: 176 SFNHMPKLRTFRLHSN 191
Score = 61.3 bits (142), Expect = 6e-09
Identities = 38/130 (29%), Positives = 62/130 (47%), Gaps = 1/130 (0%)
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
E+L + N I I F GL + VL L +N+I A+ G F L L + N+ +
Sbjct: 64 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENAIQA 123
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-L 312
+ + FRG ++ +++ N ++E F L L L L+ ++I +P ++ P L
Sbjct: 124 IPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKL 183
Query: 313 RTLSLARNQL 322
RT L N L
Sbjct: 184 RTFRLHSNHL 193
Score = 58.4 bits (135), Expect = 4e-08
Identities = 37/129 (28%), Positives = 59/129 (45%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T + N T + + L +L +L + + F + L+ L+LS+ I
Sbjct: 63 TERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENAIQ 122
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
+P AF G L+ L + +N+I+ I GAFR L + VL+LN N I +P F P+
Sbjct: 123 AIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPK 182
Query: 241 LLNLTMMRN 249
L + N
Sbjct: 183 LRTFRLHSN 191
Score = 54.0 bits (124), Expect = 9e-07
Identities = 36/154 (23%), Positives = 69/154 (44%), Gaps = 4/154 (2%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
T + + +QA+P + +T RL + N+ + F GL ++ +++ N
Sbjct: 43 TTVDCHGTGLQAIPKNIPRNTERL---ELNGNNITRIHKNDFAGLKQLRVLQLMENQIGA 99
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
++ F ++ L L L ++I+ +P + F + L+ L L +NQ+ + R L
Sbjct: 100 VERGAFDDMKELERLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGL 159
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
LTL+ N + + F + L TF + N L
Sbjct: 160 EVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 193
Score = 50.4 bits (115), Expect = 1e-05
Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
Query: 141 SLPK-LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
+LP+ +T RL ++ F+ L+ ++LS+ +I + DAF GL L L ++
Sbjct: 282 NLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLY 341
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLF 235
N+I ++ G F GL+ + +L LN N+I + F
Sbjct: 342 GNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAF 377
Score = 47.2 bits (107), Expect = 1e-04
Identities = 65/267 (24%), Positives = 109/267 (40%), Gaps = 18/267 (6%)
Query: 116 KGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELS 175
K L + LM GA D ++ L +L NA + I A F LK L+L
Sbjct: 85 KQLRVLQLMENQIGAVERGAFDDMKELERLD-LSENAIQAIPRKA--FRGATDLKNLQLD 141
Query: 176 DAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLF 235
+I+ + + AF L LE L + N I I +F + + L+ N + L
Sbjct: 142 KNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFC-DCHLA 200
Query: 236 ASTPRLLNLTMMRNSFRYLDSETFRGLD--HIQEIKIS-------NNVPLTLKEAVFSNL 286
+ L + + + RGL+ +Q+ + S VP + +
Sbjct: 201 WLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQGEAGRVPTCTLSS--GSC 258
Query: 287 PALRTLQLDLSSIRELPEEFI-SNSP--LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
PA+ T + R I +N P + + L N ++ +P +L + LS
Sbjct: 259 PAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSN 318
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
N +AE+AP+ F LR+L + V+ GN++
Sbjct: 319 NQIAEIAPDAFQGLRSLNSLVLYGNKI 345
Score = 45.6 bits (103), Expect = 3e-04
Identities = 33/111 (29%), Positives = 55/111 (49%), Gaps = 4/111 (3%)
Query: 153 GRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAF 211
G+ +T + AN+ ++ LEL+ K +P AF L ++++ N+IA I AF
Sbjct: 273 GKGLTAIPANLPETMTEIR-LELNGIKS--IPPGAFSPYRKLRRIDLSNNQIAEIAPDAF 329
Query: 212 RGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGL 262
+GL ++ L L N+I LP G+F L L + N + + F+ L
Sbjct: 330 QGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDL 380
Score = 42.7 bits (96), Expect = 0.002
Identities = 66/266 (24%), Positives = 106/266 (39%), Gaps = 20/266 (7%)
Query: 95 AEDVKTVVF-KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAG 153
A D+K + KN I+ + AF+ L ++ N TT+PV +PKL
Sbjct: 132 ATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKL-------- 183
Query: 154 RNITLHANMFANTPPLKYL-ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR 212
R LH+N L +L + + T+ G L LNV E + + +
Sbjct: 184 RTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQG 243
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISN 272
V +L+ + PA S + R + L + + + EI++
Sbjct: 244 EAGRVPTCTLSSG---SCPAMCTCSN----GIVDCRG--KGLTAIPANLPETMTEIRLEL 294
Query: 273 NVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLR 331
N ++ FS LR + L + I E+ P+ F L +L L N++ LPR V
Sbjct: 295 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFG 354
Query: 332 GQTQLTSLTLSYNAVAELAPELFADL 357
G L L L+ N + + P+ F DL
Sbjct: 355 GLYTLQLLLLNANKINCIRPDAFQDL 380
>Z24680-1|CAA80847.1| 662|Homo sapiens garp protein.
Length = 662
Score = 73.3 bits (172), Expect = 1e-12
Identities = 59/192 (30%), Positives = 93/192 (48%), Gaps = 8/192 (4%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITA---GAFRGLHNVTVLSLNKN 225
L++L+LS +I+ L AF L LE L++ N +A TA G L VT L L+ N
Sbjct: 75 LRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMATALSAGGLGPLPRVTSLDLSGN 134
Query: 226 RIQA-LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
+ + L L P L L++ NS L TFR + ++++ + +NV + +++ F
Sbjct: 135 SLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLDLHSNVLMDIEDGAFE 194
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVL-PRSVLRGQTQLTSLTLSY 343
LP L L L +S+ + + S LR L L+ N + S + + QLT L L
Sbjct: 195 GLPRLTHLNLSRNSLTCISD--FSLQQLRVLDLSCNSIEAFQTASQPQAEFQLTWLDLRE 252
Query: 344 NAVAELAPELFA 355
N + P+L A
Sbjct: 253 NKLLHF-PDLAA 263
Score = 53.6 bits (123), Expect = 1e-06
Identities = 50/185 (27%), Positives = 84/185 (45%), Gaps = 8/185 (4%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P + L+LS ++ + L L++ NEI+ + GAF+ L ++ LSL NR
Sbjct: 49 PDTETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNR 108
Query: 227 I---QALPAGLFASTPRLLNLTMMRNS-FRYLDSETFRGLDHIQEIKISNNVPLTLKEAV 282
+ AL AG PR+ +L + NS + L + + ++ N L
Sbjct: 109 LAMATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHT 168
Query: 283 FSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTL 341
F ++PAL L L + + ++ + P L L+L+RN L + L+ QL L L
Sbjct: 169 FRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSLQ---QLRVLDL 225
Query: 342 SYNAV 346
S N++
Sbjct: 226 SCNSI 230
Score = 49.2 bits (112), Expect = 3e-05
Identities = 70/259 (27%), Positives = 112/259 (43%), Gaps = 34/259 (13%)
Query: 140 RSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
R +P L L++ + + F P L +L LS +T + D + L VL+ L+
Sbjct: 170 RDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSLQQLRVLD-LSCN 228
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDS--E 257
E A TA + +T L L +N++ P A+ PRL+ L + N R +
Sbjct: 229 SIE-AFQTASQPQAEFQLTWLDLRENKLLHFPD--LAALPRLIYLNLSNNLIRLPTGPPQ 285
Query: 258 TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLS--SIRELPEEFISN-SPLRT 314
+G+ E + +PL+ S P + L LDLS I +P+ F+ + + L
Sbjct: 286 DSKGIHAPSEGWSA--LPLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCF 343
Query: 315 LSLARNQLRV--------LPRSVL---------------RGQTQLTSLTLSYNAVAELAP 351
L+L+RN LR LP +L R L +L L NA+ +L P
Sbjct: 344 LNLSRNCLRTFEARRLGSLPCLMLLDLSHNALETLELGARALGSLRTLLLQGNALRDLPP 403
Query: 352 ELFADLRALETFVMDGNEL 370
FA+L +L+ + GN +
Sbjct: 404 YTFANLASLQRLNLQGNRV 422
Score = 48.0 bits (109), Expect = 6e-05
Identities = 61/233 (26%), Positives = 102/233 (43%), Gaps = 17/233 (7%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGL 190
T + L LP++T L+ + L + P L L L++ +T L F +
Sbjct: 113 TALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDM 172
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS 250
LEQL++ N + +I GAF GL +T L+L++N + + + R+L+L+ NS
Sbjct: 173 PALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCI-SDFSLQQLRVLDLSC--NS 229
Query: 251 FRYLDSETFRGLD-HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN 309
+ + + + + + N L + + LP L L L + IR LP +
Sbjct: 230 IEAFQTASQPQAEFQLTWLDLRENKLLHFPD--LAALPRLIYLNLSNNLIR-LPTGPPQD 286
Query: 310 SPLRTLSLARNQLRVLPRSVLRGQ------TQLTSLTLSYNAVAELAPELFAD 356
S + + LP S G +QL +L LSYN + EL P+ F +
Sbjct: 287 S--KGIHAPSEGWSALPLSAPSGNASGRPLSQLLNLDLSYNEI-ELIPDSFLE 336
Score = 45.6 bits (103), Expect = 3e-04
Identities = 70/273 (25%), Positives = 111/273 (40%), Gaps = 21/273 (7%)
Query: 85 PLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPK 144
PLS LL + + ++ + + L + F L L F A ++P +L L
Sbjct: 313 PLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDL-- 370
Query: 145 LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIA 204
+H NA + L A + L+ L L + LP F L L++LN+ N ++
Sbjct: 371 -SH---NALETLELGARALGS---LRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVS 423
Query: 205 NI-------TAG--AFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
+G AF G+ ++ LSL N I+ L AG F TP L L + N +
Sbjct: 424 PCGGPDEPGPSGCVAFSGITSLRSLSLVDNEIELLRAGAFLHTP-LTELDLSSNPGLEVA 482
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
+ GL+ E+ L + + L+ L L + + LP + L L
Sbjct: 483 TGALGGLEASLEVLALQGNGLMVLQVDLPCFICLKRLNLAENRLSHLP-AWTQAVSLEVL 541
Query: 316 SLARNQLRVLPRSVLRG-QTQLTSLTLSYNAVA 347
L N +LP S + G +T L L L N ++
Sbjct: 542 DLRNNSFSLLPGSAMGGLETSLRRLYLQGNPLS 574
Score = 43.6 bits (98), Expect = 0.001
Identities = 47/182 (25%), Positives = 74/182 (40%), Gaps = 6/182 (3%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
L +L+L + K+ PD A L L LN+ N + + G + + S + +
Sbjct: 245 LTWLDLRENKLLHFPDLA--ALPRLIYLNL-SNNLIRLPTGPPQDSKGIHAPSEGWSALP 301
Query: 229 -ALPAGLFASTP--RLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSN 285
+ P+G + P +LLNL + N + L + + +S N T + +
Sbjct: 302 LSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGS 361
Query: 286 LPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
LP L L L +++ L + LRTL L N LR LP L L L N
Sbjct: 362 LPCLMLLDLSHNALETLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNR 421
Query: 346 VA 347
V+
Sbjct: 422 VS 423
>DQ084201-1|AAY86708.1| 640|Homo sapiens netrin-G1 ligand splice
variant 3 protein.
Length = 640
Score = 73.3 bits (172), Expect = 1e-12
Identities = 53/179 (29%), Positives = 89/179 (49%), Gaps = 4/179 (2%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
LN+ EN+I I +F+ L ++ +L L++N I+ + G F L L + N +
Sbjct: 81 LNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIS 140
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL-DLSSIRELPE-EFISNSPLR 313
+ F L ++E+ + NN ++ F+ +P+LR L L +L + + E F S LR
Sbjct: 141 NGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLR 200
Query: 314 TLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 372
L+LA LR +P L +L L LS N ++ + P F L L+ M +++QV
Sbjct: 201 YLNLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQV 257
Score = 71.3 bits (167), Expect = 5e-12
Identities = 52/202 (25%), Positives = 88/202 (43%), Gaps = 2/202 (0%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+ L L + +I ++ ++F L LE L + N I I GAF GL N+ L L NR+
Sbjct: 79 RLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTT 138
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPA 288
+ G F +L L + N + S F + ++ + + L+ + E F L
Sbjct: 139 ISNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSN 198
Query: 289 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
LR L L + ++RE+P L L L+ N L + +G L L + + +
Sbjct: 199 LRYLNLAMCNLREIP-NLTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQV 257
Query: 349 LAPELFADLRALETFVMDGNEL 370
+ F +L++L + N L
Sbjct: 258 IERNAFDNLQSLVEINLAHNNL 279
Score = 59.7 bits (138), Expect = 2e-08
Identities = 54/226 (23%), Positives = 98/226 (43%), Gaps = 4/226 (1%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T L+ + + V+ + L L +L+ T+ F L LEL D ++T
Sbjct: 78 TRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLT 137
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK-NRIQALPAGLFASTP 239
+ + AF+ L+ L++L + N I +I + AF + ++ L L + R+ + G F
Sbjct: 138 TISNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLS 197
Query: 240 RLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI 299
L L + + R + + T L + E+ +S N ++ F L L+ L + S I
Sbjct: 198 NLRYLNLAMCNLREIPNLT--PLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQI 255
Query: 300 RELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
+ + N L ++LA N L +LP + L + L +N
Sbjct: 256 QVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
Score = 54.4 bits (125), Expect = 7e-07
Identities = 51/196 (26%), Positives = 87/196 (44%), Gaps = 11/196 (5%)
Query: 104 KNAINPLNADAFKGLG-ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANM 162
+N I + AF GL + L +F+ TT+ L KL L ++ +
Sbjct: 109 RNHIRTIEIGAFNGLANLNTLELFD-NRLTTISNGAFVYLSKLKELWLRNNPIESIPSYA 167
Query: 163 FANTPPLKYLELSDAK-ITVLPDDAFLGLNVLEQLNVWE---NEIANITAGAFRGLHNVT 218
F P L+ L+L + K ++ + + AF GL+ L LN+ EI N+T L +
Sbjct: 168 FNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTP-----LIKLD 222
Query: 219 VLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTL 278
L L+ N + A+ G F L L M+++ + ++ F L + EI +++N L
Sbjct: 223 ELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLL 282
Query: 279 KEAVFSNLPALRTLQL 294
+F+ L L + L
Sbjct: 283 PHDLFTPLHHLERIHL 298
Score = 53.6 bits (123), Expect = 1e-06
Identities = 36/173 (20%), Positives = 78/173 (45%), Gaps = 3/173 (1%)
Query: 102 VFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNIT-LHA 160
+F N + ++ AF L + ++P +P L L + ++ +
Sbjct: 131 LFDNRLTTISNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISE 190
Query: 161 NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVL 220
F L+YL L+ + +P+ L L++L++ N ++ I G+F+GL ++ L
Sbjct: 191 GAFEGLSNLRYLNLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKL 248
Query: 221 SLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
+ +++IQ + F + L+ + + N+ L + F L H++ I + +N
Sbjct: 249 WMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
Score = 52.4 bits (120), Expect = 3e-06
Identities = 42/157 (26%), Positives = 70/157 (44%), Gaps = 4/157 (2%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N +L+L++N+IQ + F L L + RN R ++ F GL ++ +++ +N
Sbjct: 77 NTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRL 136
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLAR-NQLRVLPRSVLRGQ 333
T+ F L L+ L L + I +P + P LR L L +L + G
Sbjct: 137 TTISNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGL 196
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ L L L+ + E+ P L L L+ + GN L
Sbjct: 197 SNLRYLNLAMCNLREI-PNL-TPLIKLDELDLSGNHL 231
>BC074741-1|AAH74741.1| 345|Homo sapiens leucine-rich repeats and
transmembrane domains 1 protein.
Length = 345
Score = 73.3 bits (172), Expect = 1e-12
Identities = 44/126 (34%), Positives = 64/126 (50%), Gaps = 1/126 (0%)
Query: 220 LSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLK 279
L L N+I LPA F S P L+ L + NS L F GL H+Q + ++ N L+L+
Sbjct: 55 LHLQDNQIHHLPAFAFRSVPWLMTLNLSNNSLSNLAPGAFHGLQHLQVLNLTQNSLLSLE 114
Query: 280 EAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTS 338
+F +LP LR L L ++I LP L L++ +NQL+ L R++L +
Sbjct: 115 SRLFHSLPQLRELDLSSNNISHLPTSLGETWENLTILAVQQNQLQQLDRALLESMPSVRL 174
Query: 339 LTLSYN 344
L L N
Sbjct: 175 LLLKDN 180
Score = 69.3 bits (162), Expect = 2e-11
Identities = 39/128 (30%), Positives = 68/128 (53%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P + L L D +I LP AF + L LN+ N ++N+ GAF GL ++ VL+L +N
Sbjct: 50 PQTRTLHLQDNQIHHLPAFAFRSVPWLMTLNLSNNSLSNLAPGAFHGLQHLQVLNLTQNS 109
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
+ +L + LF S P+L L + N+ +L + +++ + + N L A+ ++
Sbjct: 110 LLSLESRLFHSLPQLRELDLSSNNISHLPTSLGETWENLTILAVQQNQLQQLDRALLESM 169
Query: 287 PALRTLQL 294
P++R L L
Sbjct: 170 PSVRLLLL 177
Score = 53.2 bits (122), Expect = 2e-06
Identities = 32/117 (27%), Positives = 56/117 (47%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L A F + P L L LS+ ++ L AF GL L+ LN+ +N + ++ + F L +
Sbjct: 65 LPAFAFRSVPWLMTLNLSNNSLSNLAPGAFHGLQHLQVLNLTQNSLLSLESRLFHSLPQL 124
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV 274
L L+ N I LP L + L L + +N + LD + ++ + + +N+
Sbjct: 125 RELDLSSNNISHLPTSLGETWENLTILAVQQNQLQQLDRALLESMPSVRLLLLKDNL 181
Score = 51.2 bits (117), Expect = 6e-06
Identities = 32/127 (25%), Positives = 62/127 (48%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L++ +N+I ++ A AFR + + L+L+ N + L G F L L + +NS L+
Sbjct: 55 LHLQDNQIHHLPAFAFRSVPWLMTLNLSNNSLSNLAPGAFHGLQHLQVLNLTQNSLLSLE 114
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
S F L ++E+ +S+N L ++ L L + + +++L + + P L
Sbjct: 115 SRLFHSLPQLRELDLSSNNISHLPTSLGETWENLTILAVQQNQLQQLDRALLESMPSVRL 174
Query: 316 SLARNQL 322
L ++ L
Sbjct: 175 LLLKDNL 181
Score = 49.6 bits (113), Expect = 2e-05
Identities = 33/131 (25%), Positives = 56/131 (42%), Gaps = 1/131 (0%)
Query: 239 PRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSS 298
P+ L + N +L + FR + + + +SNN L F L L+ L L +S
Sbjct: 50 PQTRTLHLQDNQIHHLPAFAFRSVPWLMTLNLSNNSLSNLAPGAFHGLQHLQVLNLTQNS 109
Query: 299 IRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 357
+ L + P LR L L+ N + LP S+ LT L + N + +L L +
Sbjct: 110 LLSLESRLFHSLPQLRELDLSSNNISHLPTSLGETWENLTILAVQQNQLQQLDRALLESM 169
Query: 358 RALETFVMDGN 368
++ ++ N
Sbjct: 170 PSVRLLLLKDN 180
Score = 38.3 bits (85), Expect = 0.047
Identities = 22/58 (37%), Positives = 30/58 (51%)
Query: 313 RTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
RTL L NQ+ LP R L +L LS N+++ LAP F L+ L+ + N L
Sbjct: 53 RTLHLQDNQIHHLPAFAFRSVPWLMTLNLSNNSLSNLAPGAFHGLQHLQVLNLTQNSL 110
>BC070079-1|AAH70079.1| 662|Homo sapiens LRRC32 protein protein.
Length = 662
Score = 73.3 bits (172), Expect = 1e-12
Identities = 59/192 (30%), Positives = 93/192 (48%), Gaps = 8/192 (4%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITA---GAFRGLHNVTVLSLNKN 225
L++L+LS +I+ L AF L LE L++ N +A TA G L VT L L+ N
Sbjct: 75 LRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMATALSAGGLGPLPRVTSLDLSGN 134
Query: 226 RIQA-LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
+ + L L P L L++ NS L TFR + ++++ + +NV + +++ F
Sbjct: 135 SLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLDLHSNVLMDIEDGAFE 194
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVL-PRSVLRGQTQLTSLTLSY 343
LP L L L +S+ + + S LR L L+ N + S + + QLT L L
Sbjct: 195 GLPRLTHLNLSRNSLTCISD--FSLQQLRVLDLSCNSIEAFQTASQPQAEFQLTWLDLRE 252
Query: 344 NAVAELAPELFA 355
N + P+L A
Sbjct: 253 NKLLHF-PDLAA 263
Score = 53.6 bits (123), Expect = 1e-06
Identities = 50/185 (27%), Positives = 84/185 (45%), Gaps = 8/185 (4%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P + L+LS ++ + L L++ NEI+ + GAF+ L ++ LSL NR
Sbjct: 49 PDTETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNR 108
Query: 227 I---QALPAGLFASTPRLLNLTMMRNS-FRYLDSETFRGLDHIQEIKISNNVPLTLKEAV 282
+ AL AG PR+ +L + NS + L + + ++ N L
Sbjct: 109 LAMATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHT 168
Query: 283 FSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTL 341
F ++PAL L L + + ++ + P L L+L+RN L + L+ QL L L
Sbjct: 169 FRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSLQ---QLRVLDL 225
Query: 342 SYNAV 346
S N++
Sbjct: 226 SCNSI 230
Score = 49.2 bits (112), Expect = 3e-05
Identities = 70/259 (27%), Positives = 112/259 (43%), Gaps = 34/259 (13%)
Query: 140 RSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
R +P L L++ + + F P L +L LS +T + D + L VL+ L+
Sbjct: 170 RDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSLQQLRVLD-LSCN 228
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDS--E 257
E A TA + +T L L +N++ P A+ PRL+ L + N R +
Sbjct: 229 SIE-AFQTASQPQAEFQLTWLDLRENKLLHFPD--LAALPRLIYLNLSNNLIRLPTGPPQ 285
Query: 258 TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLS--SIRELPEEFISN-SPLRT 314
+G+ E + +PL+ S P + L LDLS I +P+ F+ + + L
Sbjct: 286 DSKGIHAPSEGWSA--LPLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCF 343
Query: 315 LSLARNQLRV--------LPRSVL---------------RGQTQLTSLTLSYNAVAELAP 351
L+L+RN LR LP +L R L +L L NA+ +L P
Sbjct: 344 LNLSRNCLRTFEARRLGSLPCLMLLDLSHNALETLELGARALGSLRTLLLQGNALRDLPP 403
Query: 352 ELFADLRALETFVMDGNEL 370
FA+L +L+ + GN +
Sbjct: 404 YTFANLASLQRLNLQGNRV 422
Score = 48.0 bits (109), Expect = 6e-05
Identities = 61/233 (26%), Positives = 102/233 (43%), Gaps = 17/233 (7%)
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGL 190
T + L LP++T L+ + L + P L L L++ +T L F +
Sbjct: 113 TALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDM 172
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS 250
LEQL++ N + +I GAF GL +T L+L++N + + + R+L+L+ NS
Sbjct: 173 PALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCI-SDFSLQQLRVLDLSC--NS 229
Query: 251 FRYLDSETFRGLD-HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN 309
+ + + + + + N L + + LP L L L + IR LP +
Sbjct: 230 IEAFQTASQPQAEFQLTWLDLRENKLLHFPD--LAALPRLIYLNLSNNLIR-LPTGPPQD 286
Query: 310 SPLRTLSLARNQLRVLPRSVLRGQ------TQLTSLTLSYNAVAELAPELFAD 356
S + + LP S G +QL +L LSYN + EL P+ F +
Sbjct: 287 S--KGIHAPSEGWSALPLSAPSGNASGRPLSQLLNLDLSYNEI-ELIPDSFLE 336
Score = 45.6 bits (103), Expect = 3e-04
Identities = 70/273 (25%), Positives = 111/273 (40%), Gaps = 21/273 (7%)
Query: 85 PLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPK 144
PLS LL + + ++ + + L + F L L F A ++P +L L
Sbjct: 313 PLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDL-- 370
Query: 145 LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIA 204
+H NA + L A + L+ L L + LP F L L++LN+ N ++
Sbjct: 371 -SH---NALETLELGARALGS---LRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVS 423
Query: 205 NI-------TAG--AFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
+G AF G+ ++ LSL N I+ L AG F TP L L + N +
Sbjct: 424 PCGGPDEPGPSGCVAFSGITSLRSLSLVDNEIELLRAGAFLHTP-LTELDLSSNPGLEVA 482
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
+ GL+ E+ L + + L+ L L + + LP + L L
Sbjct: 483 TGALGGLEASLEVLALQGNGLMVLQVDLPCFICLKRLNLAENRLSHLP-AWTQAVSLEVL 541
Query: 316 SLARNQLRVLPRSVLRG-QTQLTSLTLSYNAVA 347
L N +LP S + G +T L L L N ++
Sbjct: 542 DLRNNSFSLLPGSAMGGLETSLRRLYLQGNPLS 574
Score = 43.6 bits (98), Expect = 0.001
Identities = 47/182 (25%), Positives = 74/182 (40%), Gaps = 6/182 (3%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
L +L+L + K+ PD A L L LN+ N + + G + + S + +
Sbjct: 245 LTWLDLRENKLLHFPDLA--ALPRLIYLNL-SNNLIRLPTGPPQDSKGIHAPSEGWSALP 301
Query: 229 -ALPAGLFASTP--RLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSN 285
+ P+G + P +LLNL + N + L + + +S N T + +
Sbjct: 302 LSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGS 361
Query: 286 LPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
LP L L L +++ L + LRTL L N LR LP L L L N
Sbjct: 362 LPCLMLLDLSHNALETLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNR 421
Query: 346 VA 347
V+
Sbjct: 422 VS 423
>BC048421-1|AAH48421.1| 453|Homo sapiens LOC150356 protein protein.
Length = 453
Score = 73.3 bits (172), Expect = 1e-12
Identities = 60/202 (29%), Positives = 89/202 (44%), Gaps = 2/202 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L+L +P AF GL L L++ IA + AGA GL + L L+ N++ L
Sbjct: 121 LDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLS 180
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
A PRL L + RNSF + R L + + + +N L ALR
Sbjct: 181 AAALEGAPRLGYLYLERNSFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRW 240
Query: 292 LQLDLSSIRELPEEFISNS-PLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELA 350
+ L + I E+ + + L L L RNQLR +P L G L L LS N + L
Sbjct: 241 VYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALR 300
Query: 351 PELFADL-RALETFVMDGNELQ 371
F + R+L+ ++ + L+
Sbjct: 301 DGAFQPVGRSLQHLFLNSSGLE 322
Score = 68.9 bits (161), Expect = 3e-11
Identities = 64/235 (27%), Positives = 104/235 (44%), Gaps = 7/235 (2%)
Query: 114 AFKGLG-ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYL 172
AF GLG + +L + + G + L L +L + L+ + L A P L YL
Sbjct: 135 AFPGLGHLVSLHLQHCGI-AELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYL 193
Query: 173 ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
L +P A L L L++ +N + + G + + L+ NRI +
Sbjct: 194 YLERNSFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSL 253
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLP-ALRT 291
G L L + RN R + + GL + E+++S N L++ F + +L+
Sbjct: 254 GALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQH 313
Query: 292 LQLDLSSIREL-PEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
L L+ S + ++ P F P L++L L +NQLR LP L +QL + LS N
Sbjct: 314 LFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALP--ALPSLSQLELIDLSSN 366
Score = 64.9 bits (151), Expect = 5e-10
Identities = 72/291 (24%), Positives = 111/291 (38%), Gaps = 11/291 (3%)
Query: 11 SVSACPEQCWCTDGEELNYQCSRPSTNLIVGARPRDYVNIDCMGGELVCAEFPEIDTPAT 70
+V+ CP C C E + C + P D +D P P
Sbjct: 83 AVAPCPRACVCVP-ESRHSSCEGCGLQAVPRGFPSDTQLLDLRRNHF--PSVPRAAFPGL 139
Query: 71 TQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGA 130
L SL L+ C + L + + N + L+A A +G + +
Sbjct: 140 GHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNS 199
Query: 131 QTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGL 190
VP LR+LP L L L T L+++ LS +IT + A
Sbjct: 200 FLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPA 259
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR-LLNLTMMRN 249
LE+L++ N++ + GA GL + L L+ N ++AL G F R L +L + +
Sbjct: 260 RELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSS 319
Query: 250 SFRYLDSETFRGL-DHIQEIKISNNVPLTLKEAVFSNLPALRTLQL-DLSS 298
+ F GL +Q + + N L LP+L L+L DLSS
Sbjct: 320 GLEQICPGAFSGLGPGLQSLHLQKNQLRALPA-----LPSLSQLELIDLSS 365
Score = 34.7 bits (76), Expect = 0.58
Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 286 LPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
+P R + ++ +P F S++ L L L RN +PR+ G L SL L +
Sbjct: 94 VPESRHSSCEGCGLQAVPRGFPSDTQL--LDLRRNHFPSVPRAAFPGLGHLVSLHLQHCG 151
Query: 346 VAELAPELFADLRALETFVMDGNEL 370
+AEL A L L + N+L
Sbjct: 152 IAELEAGALAGLGRLIYLYLSDNQL 176
>AY324323-1|AAQ97218.1| 479|Homo sapiens leucine-rich repeat
neuronal 6A protein.
Length = 479
Score = 73.3 bits (172), Expect = 1e-12
Identities = 67/241 (27%), Positives = 106/241 (43%), Gaps = 7/241 (2%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
+P+ V L LT ++ + + L MF + LK LE+ D + + AF GLN L
Sbjct: 26 IPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYIFHRAFSGLNSL 85
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
EQL + + + +I A LH + VL L I A+ F RL L + + + Y
Sbjct: 86 EQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI--SHWPY 143
Query: 254 LDSET---FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN- 309
LD+ T GL ++ + I++ + +L LR L L + I + +
Sbjct: 144 LDTMTPNCLYGL-NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHEL 202
Query: 310 SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNE 369
L+ + L QL V+ RG L L +S N + L +F + LET ++D N
Sbjct: 203 LRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNP 262
Query: 370 L 370
L
Sbjct: 263 L 263
Score = 58.0 bits (134), Expect = 5e-08
Identities = 46/211 (21%), Positives = 95/211 (45%), Gaps = 1/211 (0%)
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
F N L+ L L ++ ++P F GL+ L +L++ EN+I + F+ L+N+ L +
Sbjct: 7 FNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEV 66
Query: 223 NKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAV 282
N + + F+ L LT+ + + + +E L + +++ + +++
Sbjct: 67 GDNDLVYIFHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYS 126
Query: 283 FSNLPALRTLQLD-LSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTL 341
F L L+ L++ + + + L +LS+ L +P +R L L L
Sbjct: 127 FKRLYRLKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNL 186
Query: 342 SYNAVAELAPELFADLRALETFVMDGNELQV 372
SYN ++ + + +L L+ + G +L V
Sbjct: 187 SYNPISTIEGSMLHELLRLQEIQLVGGQLAV 217
Score = 55.6 bits (128), Expect = 3e-07
Identities = 28/104 (26%), Positives = 52/104 (50%)
Query: 206 ITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHI 265
+ GAF L N+ L L NR++ +P G+F L L + N L F+ L ++
Sbjct: 2 VEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNL 61
Query: 266 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN 309
+ +++ +N + + FS L +L L L+ ++ +P E +S+
Sbjct: 62 KSLEVGDNDLVYIFHRAFSGLNSLEQLTLEKCNLTSIPTEALSH 105
Score = 48.0 bits (109), Expect = 6e-05
Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 1/119 (0%)
Query: 107 INPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANT 166
++ + + GL +T+L + + T VP +R L L L+ T+ +M
Sbjct: 144 LDTMTPNCLYGLNLTSLSITHCNL-TAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHEL 202
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
L+ ++L ++ V+ AF GLN L LNV N++ + F + N+ L L+ N
Sbjct: 203 LRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSN 261
Score = 44.0 bits (99), Expect = 0.001
Identities = 24/68 (35%), Positives = 37/68 (54%)
Query: 303 PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALET 362
P F + LRTL L N+L+++P V G + LT L +S N + L +F DL L++
Sbjct: 4 PGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKS 63
Query: 363 FVMDGNEL 370
+ N+L
Sbjct: 64 LEVGDNDL 71
Score = 37.5 bits (83), Expect = 0.082
Identities = 34/137 (24%), Positives = 62/137 (45%), Gaps = 4/137 (2%)
Query: 229 ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPA 288
A+ G F + L L + N + + F GL ++ ++ IS N + L + +F +L
Sbjct: 1 AVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYN 60
Query: 289 LRTLQL-DLSSIRELPEEFISNSPLRTLSLARNQLRVLPR---SVLRGQTQLTSLTLSYN 344
L++L++ D + F + L L+L + L +P S L G L L+ N
Sbjct: 61 LKSLEVGDNDLVYIFHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNIN 120
Query: 345 AVAELAPELFADLRALE 361
A+ + + + L+ LE
Sbjct: 121 AIRDYSFKRLYRLKVLE 137
>AF225421-1|AAG09723.1| 345|Homo sapiens HT017 protein.
Length = 345
Score = 73.3 bits (172), Expect = 1e-12
Identities = 44/126 (34%), Positives = 64/126 (50%), Gaps = 1/126 (0%)
Query: 220 LSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLK 279
L L N+I LPA F S P L+ L + NS L F GL H+Q + ++ N L+L+
Sbjct: 55 LHLQDNQIHHLPAFAFRSVPWLMTLNLSNNSLSNLAPGAFHGLQHLQVLNLTQNSLLSLE 114
Query: 280 EAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTS 338
+F +LP LR L L ++I LP L L++ +NQL+ L R++L +
Sbjct: 115 SRLFHSLPQLRELDLSSNNISHLPTSLGETWENLTILAVQQNQLQQLDRALLESMPSVRL 174
Query: 339 LTLSYN 344
L L N
Sbjct: 175 LLLKDN 180
Score = 69.3 bits (162), Expect = 2e-11
Identities = 39/128 (30%), Positives = 68/128 (53%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P + L L D +I LP AF + L LN+ N ++N+ GAF GL ++ VL+L +N
Sbjct: 50 PQTRTLHLQDNQIHHLPAFAFRSVPWLMTLNLSNNSLSNLAPGAFHGLQHLQVLNLTQNS 109
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
+ +L + LF S P+L L + N+ +L + +++ + + N L A+ ++
Sbjct: 110 LLSLESRLFHSLPQLRELDLSSNNISHLPTSLGETWENLTILAVQQNQLQQLDRALLESM 169
Query: 287 PALRTLQL 294
P++R L L
Sbjct: 170 PSVRLLLL 177
Score = 53.2 bits (122), Expect = 2e-06
Identities = 32/117 (27%), Positives = 56/117 (47%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L A F + P L L LS+ ++ L AF GL L+ LN+ +N + ++ + F L +
Sbjct: 65 LPAFAFRSVPWLMTLNLSNNSLSNLAPGAFHGLQHLQVLNLTQNSLLSLESRLFHSLPQL 124
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV 274
L L+ N I LP L + L L + +N + LD + ++ + + +N+
Sbjct: 125 RELDLSSNNISHLPTSLGETWENLTILAVQQNQLQQLDRALLESMPSVRLLLLKDNL 181
Score = 51.2 bits (117), Expect = 6e-06
Identities = 32/127 (25%), Positives = 62/127 (48%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L++ +N+I ++ A AFR + + L+L+ N + L G F L L + +NS L+
Sbjct: 55 LHLQDNQIHHLPAFAFRSVPWLMTLNLSNNSLSNLAPGAFHGLQHLQVLNLTQNSLLSLE 114
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
S F L ++E+ +S+N L ++ L L + + +++L + + P L
Sbjct: 115 SRLFHSLPQLRELDLSSNNISHLPTSLGETWENLTILAVQQNQLQQLDRALLESMPSVRL 174
Query: 316 SLARNQL 322
L ++ L
Sbjct: 175 LLLKDNL 181
Score = 49.6 bits (113), Expect = 2e-05
Identities = 33/131 (25%), Positives = 56/131 (42%), Gaps = 1/131 (0%)
Query: 239 PRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSS 298
P+ L + N +L + FR + + + +SNN L F L L+ L L +S
Sbjct: 50 PQTRTLHLQDNQIHHLPAFAFRSVPWLMTLNLSNNSLSNLAPGAFHGLQHLQVLNLTQNS 109
Query: 299 IRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADL 357
+ L + P LR L L+ N + LP S+ LT L + N + +L L +
Sbjct: 110 LLSLESRLFHSLPQLRELDLSSNNISHLPTSLGETWENLTILAVQQNQLQQLDRALLESM 169
Query: 358 RALETFVMDGN 368
++ ++ N
Sbjct: 170 PSVRLLLLKDN 180
Score = 38.3 bits (85), Expect = 0.047
Identities = 22/58 (37%), Positives = 30/58 (51%)
Query: 313 RTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
RTL L NQ+ LP R L +L LS N+++ LAP F L+ L+ + N L
Sbjct: 53 RTLHLQDNQIHHLPAFAFRSVPWLMTLNLSNNSLSNLAPGAFHGLQHLQVLNLTQNSL 110
>BC101761-1|AAI01762.1| 545|Homo sapiens leucine-rich repeat LGI
family, member 2 protein.
Length = 545
Score = 71.7 bits (168), Expect = 4e-12
Identities = 38/90 (42%), Positives = 54/90 (60%)
Query: 162 MFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLS 221
MF++ P L+ L L+ T++ DDAF GL LE L + N+I I+ AFRGL ++T LS
Sbjct: 80 MFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLS 139
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
L N I+ALP +F+ L+ L + N F
Sbjct: 140 LANNHIKALPRDVFSDLDSLIELDLRGNKF 169
Score = 51.6 bits (118), Expect = 5e-06
Identities = 30/108 (27%), Positives = 58/108 (53%), Gaps = 1/108 (0%)
Query: 265 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLR 323
I + + N +K+ +FS+LP+L+ L L+ +S + ++ F L L + N++
Sbjct: 63 ISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIE 122
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
+ R+ RG LT L+L+ N + L ++F+DL +L + GN+ +
Sbjct: 123 TISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFE 170
Score = 42.7 bits (96), Expect = 0.002
Identities = 26/94 (27%), Positives = 43/94 (45%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
+++ LSL + +F+ P L L + NSF + + F GL H++ + I N
Sbjct: 62 DISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKI 121
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN 309
T+ F L L L L + I+ LP + S+
Sbjct: 122 ETISRNAFRGLRDLTHLSLANNHIKALPRDVFSD 155
Score = 41.5 bits (93), Expect = 0.005
Identities = 26/102 (25%), Positives = 45/102 (44%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L + + + D F L L+ L + N I AF GL ++ L + N+I+ +
Sbjct: 66 LSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETIS 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
F L +L++ N + L + F LD + E+ + N
Sbjct: 126 RNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGN 167
Score = 40.3 bits (90), Expect = 0.012
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 1/109 (0%)
Query: 120 ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKI 179
I++L + N G + + + LP L LN+ + + FA L+YL + KI
Sbjct: 63 ISSLSLVN-GTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKI 121
Query: 180 TVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
+ +AF GL L L++ N I + F L ++ L L N+ +
Sbjct: 122 ETISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFE 170
Score = 38.7 bits (86), Expect = 0.035
Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 2/104 (1%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
+ L++ + I F L ++ +L LN N + FA L L + N
Sbjct: 63 ISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIE 122
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDL 296
+ FRGL + + ++NN L VFS+L +L ++LDL
Sbjct: 123 TISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSL--IELDL 164
Score = 35.9 bits (79), Expect = 0.25
Identities = 23/88 (26%), Positives = 40/88 (45%)
Query: 115 FKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLEL 174
F L L++ N+ + T + D L L + + + T+ N F L +L L
Sbjct: 81 FSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSL 140
Query: 175 SDAKITVLPDDAFLGLNVLEQLNVWENE 202
++ I LP D F L+ L +L++ N+
Sbjct: 141 ANNHIKALPRDVFSDLDSLIELDLRGNK 168
>BC101759-1|AAI01760.1| 545|Homo sapiens leucine-rich repeat LGI
family, member 2 protein.
Length = 545
Score = 71.7 bits (168), Expect = 4e-12
Identities = 38/90 (42%), Positives = 54/90 (60%)
Query: 162 MFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLS 221
MF++ P L+ L L+ T++ DDAF GL LE L + N+I I+ AFRGL ++T LS
Sbjct: 80 MFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLS 139
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
L N I+ALP +F+ L+ L + N F
Sbjct: 140 LANNHIKALPRDVFSDLDSLIELDLRGNKF 169
Score = 51.6 bits (118), Expect = 5e-06
Identities = 30/108 (27%), Positives = 58/108 (53%), Gaps = 1/108 (0%)
Query: 265 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLR 323
I + + N +K+ +FS+LP+L+ L L+ +S + ++ F L L + N++
Sbjct: 63 ISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIE 122
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
+ R+ RG LT L+L+ N + L ++F+DL +L + GN+ +
Sbjct: 123 TISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFE 170
Score = 42.7 bits (96), Expect = 0.002
Identities = 26/94 (27%), Positives = 43/94 (45%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
+++ LSL + +F+ P L L + NSF + + F GL H++ + I N
Sbjct: 62 DISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKI 121
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN 309
T+ F L L L L + I+ LP + S+
Sbjct: 122 ETISRNAFRGLRDLTHLSLANNHIKALPRDVFSD 155
Score = 41.5 bits (93), Expect = 0.005
Identities = 26/102 (25%), Positives = 45/102 (44%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L + + + D F L L+ L + N I AF GL ++ L + N+I+ +
Sbjct: 66 LSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETIS 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
F L +L++ N + L + F LD + E+ + N
Sbjct: 126 RNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGN 167
Score = 40.3 bits (90), Expect = 0.012
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 1/109 (0%)
Query: 120 ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKI 179
I++L + N G + + + LP L LN+ + + FA L+YL + KI
Sbjct: 63 ISSLSLVN-GTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKI 121
Query: 180 TVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
+ +AF GL L L++ N I + F L ++ L L N+ +
Sbjct: 122 ETISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFE 170
Score = 38.7 bits (86), Expect = 0.035
Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 2/104 (1%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
+ L++ + I F L ++ +L LN N + FA L L + N
Sbjct: 63 ISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIE 122
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDL 296
+ FRGL + + ++NN L VFS+L +L ++LDL
Sbjct: 123 TISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSL--IELDL 164
Score = 35.9 bits (79), Expect = 0.25
Identities = 23/88 (26%), Positives = 40/88 (45%)
Query: 115 FKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLEL 174
F L L++ N+ + T + D L L + + + T+ N F L +L L
Sbjct: 81 FSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSL 140
Query: 175 SDAKITVLPDDAFLGLNVLEQLNVWENE 202
++ I LP D F L+ L +L++ N+
Sbjct: 141 ANNHIKALPRDVFSDLDSLIELDLRGNK 168
>AJ487958-1|CAD32305.1| 545|Homo sapiens LGI1-like protein 2
protein.
Length = 545
Score = 71.7 bits (168), Expect = 4e-12
Identities = 38/90 (42%), Positives = 54/90 (60%)
Query: 162 MFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLS 221
MF++ P L+ L L+ T++ DDAF GL LE L + N+I I+ AFRGL ++T LS
Sbjct: 80 MFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLS 139
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
L N I+ALP +F+ L+ L + N F
Sbjct: 140 LANNHIKALPRDVFSDLDSLIELDLRGNKF 169
Score = 51.6 bits (118), Expect = 5e-06
Identities = 30/108 (27%), Positives = 58/108 (53%), Gaps = 1/108 (0%)
Query: 265 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLR 323
I + + N +K+ +FS+LP+L+ L L+ +S + ++ F L L + N++
Sbjct: 63 ISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIE 122
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
+ R+ RG LT L+L+ N + L ++F+DL +L + GN+ +
Sbjct: 123 TISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFE 170
Score = 42.7 bits (96), Expect = 0.002
Identities = 26/94 (27%), Positives = 43/94 (45%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
+++ LSL + +F+ P L L + NSF + + F GL H++ + I N
Sbjct: 62 DISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKI 121
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN 309
T+ F L L L L + I+ LP + S+
Sbjct: 122 ETISRNAFRGLRDLTHLSLANNHIKALPRDVFSD 155
Score = 41.5 bits (93), Expect = 0.005
Identities = 26/102 (25%), Positives = 45/102 (44%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L + + + D F L L+ L + N I AF GL ++ L + N+I+ +
Sbjct: 66 LSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETIS 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
F L +L++ N + L + F LD + E+ + N
Sbjct: 126 RNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGN 167
Score = 40.3 bits (90), Expect = 0.012
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 1/109 (0%)
Query: 120 ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKI 179
I++L + N G + + + LP L LN+ + + FA L+YL + KI
Sbjct: 63 ISSLSLVN-GTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKI 121
Query: 180 TVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
+ +AF GL L L++ N I + F L ++ L L N+ +
Sbjct: 122 ETISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFE 170
Score = 38.7 bits (86), Expect = 0.035
Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 2/104 (1%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
+ L++ + I F L ++ +L LN N + FA L L + N
Sbjct: 63 ISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIE 122
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDL 296
+ FRGL + + ++NN L VFS+L +L ++LDL
Sbjct: 123 TISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSL--IELDL 164
Score = 35.9 bits (79), Expect = 0.25
Identities = 23/88 (26%), Positives = 40/88 (45%)
Query: 115 FKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLEL 174
F L L++ N+ + T + D L L + + + T+ N F L +L L
Sbjct: 81 FSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSL 140
Query: 175 SDAKITVLPDDAFLGLNVLEQLNVWENE 202
++ I LP D F L+ L +L++ N+
Sbjct: 141 ANNHIKALPRDVFSDLDSLIELDLRGNK 168
>AJ487516-1|CAD31784.1| 545|Homo sapiens leucine-rich glioma
inactivated protein 2 protein.
Length = 545
Score = 71.7 bits (168), Expect = 4e-12
Identities = 38/90 (42%), Positives = 54/90 (60%)
Query: 162 MFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLS 221
MF++ P L+ L L+ T++ DDAF GL LE L + N+I I+ AFRGL ++T LS
Sbjct: 80 MFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLS 139
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
L N I+ALP +F+ L+ L + N F
Sbjct: 140 LANNHIKALPRDVFSDLDSLIELDLRGNKF 169
Score = 51.6 bits (118), Expect = 5e-06
Identities = 30/108 (27%), Positives = 58/108 (53%), Gaps = 1/108 (0%)
Query: 265 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLR 323
I + + N +K+ +FS+LP+L+ L L+ +S + ++ F L L + N++
Sbjct: 63 ISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIE 122
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
+ R+ RG LT L+L+ N + L ++F+DL +L + GN+ +
Sbjct: 123 TISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFE 170
Score = 42.7 bits (96), Expect = 0.002
Identities = 26/94 (27%), Positives = 43/94 (45%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
+++ LSL + +F+ P L L + NSF + + F GL H++ + I N
Sbjct: 62 DISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKI 121
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN 309
T+ F L L L L + I+ LP + S+
Sbjct: 122 ETISRNAFRGLRDLTHLSLANNHIKALPRDVFSD 155
Score = 41.5 bits (93), Expect = 0.005
Identities = 26/102 (25%), Positives = 45/102 (44%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L + + + D F L L+ L + N I AF GL ++ L + N+I+ +
Sbjct: 66 LSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETIS 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
F L +L++ N + L + F LD + E+ + N
Sbjct: 126 RNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGN 167
Score = 40.3 bits (90), Expect = 0.012
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 1/109 (0%)
Query: 120 ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKI 179
I++L + N G + + + LP L LN+ + + FA L+YL + KI
Sbjct: 63 ISSLSLVN-GTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKI 121
Query: 180 TVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
+ +AF GL L L++ N I + F L ++ L L N+ +
Sbjct: 122 ETISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFE 170
Score = 38.7 bits (86), Expect = 0.035
Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 2/104 (1%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
+ L++ + I F L ++ +L LN N + FA L L + N
Sbjct: 63 ISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIE 122
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDL 296
+ FRGL + + ++NN L VFS+L +L ++LDL
Sbjct: 123 TISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSL--IELDL 164
Score = 35.9 bits (79), Expect = 0.25
Identities = 23/88 (26%), Positives = 40/88 (45%)
Query: 115 FKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLEL 174
F L L++ N+ + T + D L L + + + T+ N F L +L L
Sbjct: 81 FSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSL 140
Query: 175 SDAKITVLPDDAFLGLNVLEQLNVWENE 202
++ I LP D F L+ L +L++ N+
Sbjct: 141 ANNHIKALPRDVFSDLDSLIELDLRGNK 168
>AF467955-1|AAM49553.1| 545|Homo sapiens LGI2 protein.
Length = 545
Score = 71.7 bits (168), Expect = 4e-12
Identities = 38/90 (42%), Positives = 54/90 (60%)
Query: 162 MFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLS 221
MF++ P L+ L L+ T++ DDAF GL LE L + N+I I+ AFRGL ++T LS
Sbjct: 80 MFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLS 139
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
L N I+ALP +F+ L+ L + N F
Sbjct: 140 LANNHIKALPRDVFSDLDSLIELDLRGNKF 169
Score = 51.6 bits (118), Expect = 5e-06
Identities = 30/108 (27%), Positives = 58/108 (53%), Gaps = 1/108 (0%)
Query: 265 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLR 323
I + + N +K+ +FS+LP+L+ L L+ +S + ++ F L L + N++
Sbjct: 63 ISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIE 122
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
+ R+ RG LT L+L+ N + L ++F+DL +L + GN+ +
Sbjct: 123 TISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFE 170
Score = 42.7 bits (96), Expect = 0.002
Identities = 26/94 (27%), Positives = 43/94 (45%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
+++ LSL + +F+ P L L + NSF + + F GL H++ + I N
Sbjct: 62 DISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKI 121
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN 309
T+ F L L L L + I+ LP + S+
Sbjct: 122 ETISRNAFRGLRDLTHLSLANNHIKALPRDVFSD 155
Score = 41.5 bits (93), Expect = 0.005
Identities = 26/102 (25%), Positives = 45/102 (44%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L + + + D F L L+ L + N I AF GL ++ L + N+I+ +
Sbjct: 66 LSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETIS 125
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
F L +L++ N + L + F LD + E+ + N
Sbjct: 126 RNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGN 167
Score = 40.3 bits (90), Expect = 0.012
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 1/109 (0%)
Query: 120 ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKI 179
I++L + N G + + + LP L LN+ + + FA L+YL + KI
Sbjct: 63 ISSLSLVN-GTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKI 121
Query: 180 TVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
+ +AF GL L L++ N I + F L ++ L L N+ +
Sbjct: 122 ETISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFE 170
Score = 38.7 bits (86), Expect = 0.035
Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 2/104 (1%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
+ L++ + I F L ++ +L LN N + FA L L + N
Sbjct: 63 ISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIE 122
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDL 296
+ FRGL + + ++NN L VFS+L +L ++LDL
Sbjct: 123 TISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSL--IELDL 164
Score = 35.9 bits (79), Expect = 0.25
Identities = 23/88 (26%), Positives = 40/88 (45%)
Query: 115 FKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLEL 174
F L L++ N+ + T + D L L + + + T+ N F L +L L
Sbjct: 81 FSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSL 140
Query: 175 SDAKITVLPDDAFLGLNVLEQLNVWENE 202
++ I LP D F L+ L +L++ N+
Sbjct: 141 ANNHIKALPRDVFSDLDSLIELDLRGNK 168
>AB067503-1|BAB67809.1| 542|Homo sapiens KIAA1916 protein protein.
Length = 542
Score = 71.7 bits (168), Expect = 4e-12
Identities = 38/90 (42%), Positives = 54/90 (60%)
Query: 162 MFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLS 221
MF++ P L+ L L+ T++ DDAF GL LE L + N+I I+ AFRGL ++T LS
Sbjct: 77 MFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLS 136
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSF 251
L N I+ALP +F+ L+ L + N F
Sbjct: 137 LANNHIKALPRDVFSDLDSLIELDLRGNKF 166
Score = 51.6 bits (118), Expect = 5e-06
Identities = 30/108 (27%), Positives = 58/108 (53%), Gaps = 1/108 (0%)
Query: 265 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLR 323
I + + N +K+ +FS+LP+L+ L L+ +S + ++ F L L + N++
Sbjct: 60 ISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIE 119
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
+ R+ RG LT L+L+ N + L ++F+DL +L + GN+ +
Sbjct: 120 TISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFE 167
Score = 42.7 bits (96), Expect = 0.002
Identities = 26/94 (27%), Positives = 43/94 (45%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
+++ LSL + +F+ P L L + NSF + + F GL H++ + I N
Sbjct: 59 DISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKI 118
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN 309
T+ F L L L L + I+ LP + S+
Sbjct: 119 ETISRNAFRGLRDLTHLSLANNHIKALPRDVFSD 152
Score = 41.5 bits (93), Expect = 0.005
Identities = 26/102 (25%), Positives = 45/102 (44%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L L + + + D F L L+ L + N I AF GL ++ L + N+I+ +
Sbjct: 63 LSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETIS 122
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
F L +L++ N + L + F LD + E+ + N
Sbjct: 123 RNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGN 164
Score = 40.3 bits (90), Expect = 0.012
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 1/109 (0%)
Query: 120 ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKI 179
I++L + N G + + + LP L LN+ + + FA L+YL + KI
Sbjct: 60 ISSLSLVN-GTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKI 118
Query: 180 TVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
+ +AF GL L L++ N I + F L ++ L L N+ +
Sbjct: 119 ETISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFE 167
Score = 38.7 bits (86), Expect = 0.035
Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 2/104 (1%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
+ L++ + I F L ++ +L LN N + FA L L + N
Sbjct: 60 ISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIE 119
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDL 296
+ FRGL + + ++NN L VFS+L +L ++LDL
Sbjct: 120 TISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSL--IELDL 161
Score = 35.9 bits (79), Expect = 0.25
Identities = 23/88 (26%), Positives = 40/88 (45%)
Query: 115 FKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLEL 174
F L L++ N+ + T + D L L + + + T+ N F L +L L
Sbjct: 78 FSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSL 137
Query: 175 SDAKITVLPDDAFLGLNVLEQLNVWENE 202
++ I LP D F L+ L +L++ N+
Sbjct: 138 ANNHIKALPRDVFSDLDSLIELDLRGNK 165
>L01131-1|AAA52301.1| 347|Homo sapiens decorin protein.
Length = 347
Score = 71.3 bits (167), Expect = 5e-12
Identities = 59/222 (26%), Positives = 107/222 (48%), Gaps = 10/222 (4%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P L+L + KIT + D F L L L + N+I+ ++ GAF L + L L+KN+
Sbjct: 81 PDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQ 140
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT---LKEAVF 283
++ LP + L L N + TF GL+ + I++ N PL ++ F
Sbjct: 141 LKELPEKM---PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTN-PLKSSGIENGAF 196
Query: 284 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+ L +++ ++I +P+ + L L L N++ + + L+G L L LS+
Sbjct: 197 QGMKKLSYIRIADTNITSIPQGLPPS--LTELHLDGNKISRVDAASLKGLNNLAKLGLSF 254
Query: 344 NAVAELAPELFADLRALETFVMDGNEL-QVGYVYIDDILVAG 384
N+++ + A+ L +D N+L +V Y++ ++I V G
Sbjct: 255 NSISAVDNGSLANTPHLRELHLDNNKLTRVVYLHNNNISVVG 296
>AB016816-1|BAA74737.1| 1052|Homo sapiens MASL1 protein.
Length = 1052
Score = 71.3 bits (167), Expect = 5e-12
Identities = 54/181 (29%), Positives = 82/181 (45%), Gaps = 3/181 (1%)
Query: 190 LNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
L +E LN+ N + + G L ++ VL L +NR LP + L L + N
Sbjct: 62 LGDIEALNLGNNGLEEVPEGLGSALGSLRVLVLRRNRFARLPPAVAELGHHLTELDVSHN 121
Query: 250 SFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN 309
L +E L ++++ +S+N L A L L L + + + LP+
Sbjct: 122 RLTALGAEVVSALRELRKLNLSHN-QLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCL 180
Query: 310 SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNE 369
S LRTL + NQL PR +L+ L L +S N + L PE + LRAL+ + G E
Sbjct: 181 SRLRTLDVDHNQLTAFPRQLLQ-LVALEELDVSSNRLRGL-PEDISALRALKILWLSGAE 238
Query: 370 L 370
L
Sbjct: 239 L 239
Score = 63.3 bits (147), Expect = 1e-09
Identities = 60/188 (31%), Positives = 91/188 (48%), Gaps = 7/188 (3%)
Query: 141 SLPKLTHFR-LNAGRN-ITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
SL L+ R L+ N +T L+ L++S ++ LP+D L L+ L +
Sbjct: 176 SLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPED-ISALRALKILWL 234
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET 258
E+ + AG F L ++ L L+ N +QALPA F+ RL L + N F +
Sbjct: 235 SGAELGTLPAG-FCELASLESLMLDNNGLQALPAQ-FSCLQRLKMLNLSSNLFEEFPAAL 292
Query: 259 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLA 318
L ++E+ +S N LT ++ S L L TL LD + IR LP+ + + L L L
Sbjct: 293 LP-LAGLEELYLSRN-QLTSVPSLISGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQ 350
Query: 319 RNQLRVLP 326
NQ+ VLP
Sbjct: 351 GNQIAVLP 358
Score = 56.8 bits (131), Expect = 1e-07
Identities = 45/158 (28%), Positives = 74/158 (46%), Gaps = 2/158 (1%)
Query: 214 LHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L ++ L+L N ++ +P GL ++ L L + RN F L H+ E+ +S+N
Sbjct: 62 LGDIEALNLGNNGLEEVPEGLGSALGSLRVLVLRRNRFARLPPAVAELGHHLTELDVSHN 121
Query: 274 VPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQ 333
L V S L LR L L + + LP + + + L L ++ N+L LP S L
Sbjct: 122 RLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDS-LSCL 180
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
++L +L + +N + P L ALE + N L+
Sbjct: 181 SRLRTLDVDHNQLTAF-PRQLLQLVALEELDVSSNRLR 217
>CR457397-1|CAG33678.1| 708|Homo sapiens LRRN3 protein.
Length = 708
Score = 70.9 bits (166), Expect = 7e-12
Identities = 64/264 (24%), Positives = 120/264 (45%), Gaps = 7/264 (2%)
Query: 65 IDTPATTQLPSLSLRECSLP--PLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITA 122
I+ QL S+ L E L P CL + + +++ + N ++ ++ AF GL
Sbjct: 110 INVKKMPQLLSVYLEENKLTELPEKCLSELSNLQEL--YINHNLLSTISPGAFIGLHNLL 167
Query: 123 LMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVL 182
+ N+ + +LP L + I + F L+ L ++ +T +
Sbjct: 168 RLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEI 227
Query: 183 PDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLL 242
PD+A +GL LE ++ ++N + + A + + N+ L LNKN I + G F++ L
Sbjct: 228 PDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLK 287
Query: 243 NLTMMR-NSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPALRTLQLDLSSIR 300
L + +DS L +++I+ +NN L+ + F LP L +L L+ +++
Sbjct: 288 ELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALS 347
Query: 301 ELPEEFISNSP-LRTLSLARNQLR 323
L I + P L+ +S+ N +R
Sbjct: 348 ALYHGTIESLPNLKEISIHSNPIR 371
Score = 62.1 bits (144), Expect = 3e-09
Identities = 49/200 (24%), Positives = 92/200 (46%), Gaps = 5/200 (2%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P L + L + K+T LP+ L+ L++L + N ++ I+ GAF GLHN+ L LN NR
Sbjct: 116 PQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNR 175
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
+Q + + F + P L L + N + F+ L +++ + I+ + + L
Sbjct: 176 LQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGL 235
Query: 287 PALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS--- 342
L ++ + + ++P + L+ L L +N + + R L L ++
Sbjct: 236 ENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMP 295
Query: 343 -YNAVAELAPELFADLRALE 361
++ LA + DLR +E
Sbjct: 296 ELISIDSLAVDNLPDLRKIE 315
Score = 60.5 bits (140), Expect = 1e-08
Identities = 64/289 (22%), Positives = 110/289 (38%), Gaps = 9/289 (3%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITAL 123
E T L L L + +L ++ + K + + + +N + L L
Sbjct: 85 EYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQE 144
Query: 124 MMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLP 183
+ N +T+ L L LN+ R +++ F P L+ L + + I +
Sbjct: 145 LYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIK 204
Query: 184 DDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLN 243
D F L L L + + I A GL N+ +S NR+ +P L
Sbjct: 205 DMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKF 264
Query: 244 LTMMRNSFRYLDSETFRGLDHIQEIKISNNVP--LTLKEAVFSNLPALRTLQLD----LS 297
L + +N + F + H++E+ I NN+P +++ NLP LR ++ LS
Sbjct: 265 LDLNKNPINRIRRGDFSNMLHLKELGI-NNMPELISIDSLAVDNLPDLRKIEATNNPRLS 323
Query: 298 SIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAV 346
I P F L +L L N L L + L +++ N +
Sbjct: 324 YIH--PNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPI 370
Score = 34.7 bits (76), Expect = 0.58
Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
NL L Q +LSS+ + + + L ++ L N+L LP L + L L +++N
Sbjct: 93 NLTGLDLSQNNLSSVTNINVKKMPQ--LLSVYLEENKLTELPEKCLSELSNLQELYINHN 150
Query: 345 AVAELAPELFADLRALETFVMDGNELQV 372
++ ++P F L L ++ N LQ+
Sbjct: 151 LLSTISPGAFIGLHNLLRLHLNSNRLQM 178
>BC035133-1|AAH35133.1| 708|Homo sapiens leucine rich repeat
neuronal 3 protein.
Length = 708
Score = 70.9 bits (166), Expect = 7e-12
Identities = 64/264 (24%), Positives = 120/264 (45%), Gaps = 7/264 (2%)
Query: 65 IDTPATTQLPSLSLRECSLP--PLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITA 122
I+ QL S+ L E L P CL + + +++ + N ++ ++ AF GL
Sbjct: 110 INVKKMPQLLSVYLEENKLTELPEKCLSELSNLQEL--YINHNLLSTISPGAFIGLHNLL 167
Query: 123 LMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVL 182
+ N+ + +LP L + I + F L+ L ++ +T +
Sbjct: 168 RLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEI 227
Query: 183 PDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLL 242
PD+A +GL LE ++ ++N + + A + + N+ L LNKN I + G F++ L
Sbjct: 228 PDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLK 287
Query: 243 NLTMMR-NSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPALRTLQLDLSSIR 300
L + +DS L +++I+ +NN L+ + F LP L +L L+ +++
Sbjct: 288 ELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALS 347
Query: 301 ELPEEFISNSP-LRTLSLARNQLR 323
L I + P L+ +S+ N +R
Sbjct: 348 ALYHGTIESLPNLKEISIHSNPIR 371
Score = 62.1 bits (144), Expect = 3e-09
Identities = 65/289 (22%), Positives = 111/289 (38%), Gaps = 9/289 (3%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITAL 123
E T L SL L + +L ++ + K + + + +N + L L
Sbjct: 85 EYSTDFPVNLTSLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQE 144
Query: 124 MMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLP 183
+ N +T+ L L LN+ R +++ F P L+ L + + I +
Sbjct: 145 LYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIK 204
Query: 184 DDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLN 243
D F L L L + + I A GL N+ +S NR+ +P L
Sbjct: 205 DMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKF 264
Query: 244 LTMMRNSFRYLDSETFRGLDHIQEIKISNNVP--LTLKEAVFSNLPALRTLQLD----LS 297
L + +N + F + H++E+ I NN+P +++ NLP LR ++ LS
Sbjct: 265 LDLNKNPINRIRRGDFSNMLHLKELGI-NNMPELISIDSLAVDNLPDLRKIEATNNPRLS 323
Query: 298 SIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAV 346
I P F L +L L N L L + L +++ N +
Sbjct: 324 YIH--PNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPI 370
Score = 62.1 bits (144), Expect = 3e-09
Identities = 49/200 (24%), Positives = 92/200 (46%), Gaps = 5/200 (2%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P L + L + K+T LP+ L+ L++L + N ++ I+ GAF GLHN+ L LN NR
Sbjct: 116 PQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNR 175
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
+Q + + F + P L L + N + F+ L +++ + I+ + + L
Sbjct: 176 LQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGL 235
Query: 287 PALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS--- 342
L ++ + + ++P + L+ L L +N + + R L L ++
Sbjct: 236 ENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMP 295
Query: 343 -YNAVAELAPELFADLRALE 361
++ LA + DLR +E
Sbjct: 296 ELISIDSLAVDNLPDLRKIE 315
Score = 35.1 bits (77), Expect = 0.44
Identities = 24/88 (27%), Positives = 44/88 (50%), Gaps = 2/88 (2%)
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
NL +L Q +LSS+ + + + L ++ L N+L LP L + L L +++N
Sbjct: 93 NLTSLDLSQNNLSSVTNINVKKMPQ--LLSVYLEENKLTELPEKCLSELSNLQELYINHN 150
Query: 345 AVAELAPELFADLRALETFVMDGNELQV 372
++ ++P F L L ++ N LQ+
Sbjct: 151 LLSTISPGAFIGLHNLLRLHLNSNRLQM 178
>AY358280-1|AAQ88647.1| 708|Homo sapiens LRRN3 protein.
Length = 708
Score = 70.9 bits (166), Expect = 7e-12
Identities = 64/264 (24%), Positives = 120/264 (45%), Gaps = 7/264 (2%)
Query: 65 IDTPATTQLPSLSLRECSLP--PLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITA 122
I+ QL S+ L E L P CL + + +++ + N ++ ++ AF GL
Sbjct: 110 INVKKMPQLLSVYLEENKLTELPEKCLSELSNLQEL--YINHNLLSTISPGAFIGLHNLL 167
Query: 123 LMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVL 182
+ N+ + +LP L + I + F L+ L ++ +T +
Sbjct: 168 RLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEI 227
Query: 183 PDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLL 242
PD+A +GL LE ++ ++N + + A + + N+ L LNKN I + G F++ L
Sbjct: 228 PDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLK 287
Query: 243 NLTMMR-NSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPALRTLQLDLSSIR 300
L + +DS L +++I+ +NN L+ + F LP L +L L+ +++
Sbjct: 288 ELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALS 347
Query: 301 ELPEEFISNSP-LRTLSLARNQLR 323
L I + P L+ +S+ N +R
Sbjct: 348 ALYHGTIESLPNLKEISIHSNPIR 371
Score = 62.1 bits (144), Expect = 3e-09
Identities = 49/200 (24%), Positives = 92/200 (46%), Gaps = 5/200 (2%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P L + L + K+T LP+ L+ L++L + N ++ I+ GAF GLHN+ L LN NR
Sbjct: 116 PQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNR 175
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
+Q + + F + P L L + N + F+ L +++ + I+ + + L
Sbjct: 176 LQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGL 235
Query: 287 PALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS--- 342
L ++ + + ++P + L+ L L +N + + R L L ++
Sbjct: 236 ENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMP 295
Query: 343 -YNAVAELAPELFADLRALE 361
++ LA + DLR +E
Sbjct: 296 ELISIDSLAVDNLPDLRKIE 315
Score = 60.5 bits (140), Expect = 1e-08
Identities = 64/289 (22%), Positives = 110/289 (38%), Gaps = 9/289 (3%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITAL 123
E T L L L + +L ++ + K + + + +N + L L
Sbjct: 85 EYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQE 144
Query: 124 MMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLP 183
+ N +T+ L L LN+ R +++ F P L+ L + + I +
Sbjct: 145 LYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIK 204
Query: 184 DDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLN 243
D F L L L + + I A GL N+ +S NR+ +P L
Sbjct: 205 DMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKF 264
Query: 244 LTMMRNSFRYLDSETFRGLDHIQEIKISNNVP--LTLKEAVFSNLPALRTLQLD----LS 297
L + +N + F + H++E+ I NN+P +++ NLP LR ++ LS
Sbjct: 265 LDLNKNPINRIRRGDFSNMLHLKELGI-NNMPELISIDSLAVDNLPDLRKIEATNNPRLS 323
Query: 298 SIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAV 346
I P F L +L L N L L + L +++ N +
Sbjct: 324 YIH--PNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPI 370
Score = 34.7 bits (76), Expect = 0.58
Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
NL L Q +LSS+ + + + L ++ L N+L LP L + L L +++N
Sbjct: 93 NLTGLDLSQNNLSSVTNINVKKMPQ--LLSVYLEENKLTELPEKCLSELSNLQELYINHN 150
Query: 345 AVAELAPELFADLRALETFVMDGNELQV 372
++ ++P F L L ++ N LQ+
Sbjct: 151 LLSTISPGAFIGLHNLLRLHLNSNRLQM 178
>AF134481-1|AAP97258.1| 708|Homo sapiens leucine-rich repeat
protein protein.
Length = 708
Score = 70.9 bits (166), Expect = 7e-12
Identities = 64/264 (24%), Positives = 120/264 (45%), Gaps = 7/264 (2%)
Query: 65 IDTPATTQLPSLSLRECSLP--PLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITA 122
I+ QL S+ L E L P CL + + +++ + N ++ ++ AF GL
Sbjct: 110 INVKKMPQLLSVYLEENKLTELPEKCLSELSNLQEL--YINHNLLSTISPGAFIGLHNLL 167
Query: 123 LMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVL 182
+ N+ + +LP L + I + F L+ L ++ +T +
Sbjct: 168 RLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEI 227
Query: 183 PDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLL 242
PD+A +GL LE ++ ++N + + A + + N+ L LNKN I + G F++ L
Sbjct: 228 PDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLK 287
Query: 243 NLTMMR-NSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPALRTLQLDLSSIR 300
L + +DS L +++I+ +NN L+ + F LP L +L L+ +++
Sbjct: 288 ELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALS 347
Query: 301 ELPEEFISNSP-LRTLSLARNQLR 323
L I + P L+ +S+ N +R
Sbjct: 348 ALYHGTIESLPNLKEISIHSNPIR 371
Score = 62.1 bits (144), Expect = 3e-09
Identities = 49/200 (24%), Positives = 92/200 (46%), Gaps = 5/200 (2%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P L + L + K+T LP+ L+ L++L + N ++ I+ GAF GLHN+ L LN NR
Sbjct: 116 PQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNR 175
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
+Q + + F + P L L + N + F+ L +++ + I+ + + L
Sbjct: 176 LQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGL 235
Query: 287 PALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS--- 342
L ++ + + ++P + L+ L L +N + + R L L ++
Sbjct: 236 ENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMP 295
Query: 343 -YNAVAELAPELFADLRALE 361
++ LA + DLR +E
Sbjct: 296 ELISIDSLAVDNLPDLRKIE 315
Score = 60.5 bits (140), Expect = 1e-08
Identities = 64/289 (22%), Positives = 110/289 (38%), Gaps = 9/289 (3%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITAL 123
E T L L L + +L ++ + K + + + +N + L L
Sbjct: 85 EYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQE 144
Query: 124 MMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLP 183
+ N +T+ L L LN+ R +++ F P L+ L + + I +
Sbjct: 145 LYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIK 204
Query: 184 DDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLN 243
D F L L L + + I A GL N+ +S NR+ +P L
Sbjct: 205 DMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKF 264
Query: 244 LTMMRNSFRYLDSETFRGLDHIQEIKISNNVP--LTLKEAVFSNLPALRTLQLD----LS 297
L + +N + F + H++E+ I NN+P +++ NLP LR ++ LS
Sbjct: 265 LDLNKNPINRIRRGDFSNMLHLKELGI-NNMPELISIDSLAVDNLPDLRKIEATNNPRLS 323
Query: 298 SIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAV 346
I P F L +L L N L L + L +++ N +
Sbjct: 324 YIH--PNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPI 370
Score = 34.7 bits (76), Expect = 0.58
Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
NL L Q +LSS+ + + + L ++ L N+L LP L + L L +++N
Sbjct: 93 NLTGLDLSQNNLSSVTNINVKKMPQ--LLSVYLEENKLTELPEKCLSELSNLQELYINHN 150
Query: 345 AVAELAPELFADLRALETFVMDGNELQV 372
++ ++P F L L ++ N LQ+
Sbjct: 151 LLSTISPGAFIGLHNLLRLHLNSNRLQM 178
>AB060967-1|BAB47184.1| 708|Homo sapiens neuronal leucine-rich
repeat protein-3 protein.
Length = 708
Score = 70.9 bits (166), Expect = 7e-12
Identities = 64/264 (24%), Positives = 120/264 (45%), Gaps = 7/264 (2%)
Query: 65 IDTPATTQLPSLSLRECSLP--PLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITA 122
I+ QL S+ L E L P CL + + +++ + N ++ ++ AF GL
Sbjct: 110 INVKKMPQLLSVYLEENKLTELPEKCLSELSNLQEL--YINHNLLSTISPGAFIGLHNLL 167
Query: 123 LMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVL 182
+ N+ + +LP L + I + F L+ L ++ +T +
Sbjct: 168 RLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEI 227
Query: 183 PDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLL 242
PD+A +GL LE ++ ++N + + A + + N+ L LNKN I + G F++ L
Sbjct: 228 PDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLK 287
Query: 243 NLTMMR-NSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPALRTLQLDLSSIR 300
L + +DS L +++I+ +NN L+ + F LP L +L L+ +++
Sbjct: 288 ELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALS 347
Query: 301 ELPEEFISNSP-LRTLSLARNQLR 323
L I + P L+ +S+ N +R
Sbjct: 348 ALYHGTIESLPNLKEISIHSNPIR 371
Score = 62.1 bits (144), Expect = 3e-09
Identities = 49/200 (24%), Positives = 92/200 (46%), Gaps = 5/200 (2%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P L + L + K+T LP+ L+ L++L + N ++ I+ GAF GLHN+ L LN NR
Sbjct: 116 PQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNR 175
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
+Q + + F + P L L + N + F+ L +++ + I+ + + L
Sbjct: 176 LQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGL 235
Query: 287 PALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLS--- 342
L ++ + + ++P + L+ L L +N + + R L L ++
Sbjct: 236 ENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMP 295
Query: 343 -YNAVAELAPELFADLRALE 361
++ LA + DLR +E
Sbjct: 296 ELISIDSLAVDNLPDLRKIE 315
Score = 60.5 bits (140), Expect = 1e-08
Identities = 64/289 (22%), Positives = 110/289 (38%), Gaps = 9/289 (3%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITAL 123
E T L L L + +L ++ + K + + + +N + L L
Sbjct: 85 EYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQE 144
Query: 124 MMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLP 183
+ N +T+ L L LN+ R +++ F P L+ L + + I +
Sbjct: 145 LYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIK 204
Query: 184 DDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLN 243
D F L L L + + I A GL N+ +S NR+ +P L
Sbjct: 205 DMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKF 264
Query: 244 LTMMRNSFRYLDSETFRGLDHIQEIKISNNVP--LTLKEAVFSNLPALRTLQLD----LS 297
L + +N + F + H++E+ I NN+P +++ NLP LR ++ LS
Sbjct: 265 LDLNKNPINRIRRGDFSNMLHLKELGI-NNMPELISIDSLAVDNLPDLRKIEATNNPRLS 323
Query: 298 SIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAV 346
I P F L +L L N L L + L +++ N +
Sbjct: 324 YIH--PNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPI 370
Score = 34.7 bits (76), Expect = 0.58
Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Query: 285 NLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
NL L Q +LSS+ + + + L ++ L N+L LP L + L L +++N
Sbjct: 93 NLTGLDLSQNNLSSVTNINVKKMPQ--LLSVYLEENKLTELPEKCLSELSNLQELYINHN 150
Query: 345 AVAELAPELFADLRALETFVMDGNELQV 372
++ ++P F L L ++ N LQ+
Sbjct: 151 LLSTISPGAFIGLHNLLRLHLNSNRLQM 178
>DQ084202-1|AAY86709.1| 640|Homo sapiens netrin-G1 ligand splice
variant 4 protein.
Length = 640
Score = 70.5 bits (165), Expect = 9e-12
Identities = 52/202 (25%), Positives = 87/202 (43%), Gaps = 2/202 (0%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+ L L + +I ++ ++F L LE L + N I I GAF G N L L NR+
Sbjct: 79 RLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGPANPNTLELFDNRLAT 138
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPA 288
+P G F +L L + N + S F + ++ + + L+ + E F L
Sbjct: 139 IPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSN 198
Query: 289 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
LR L L + ++RE+P L L L+ N L + +G L L + + +
Sbjct: 199 LRYLNLAMCNLREIP-NLTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIRV 257
Query: 349 LAPELFADLRALETFVMDGNEL 370
+ F +L++L + N L
Sbjct: 258 IERNAFDNLQSLVEINLAHNNL 279
Score = 68.5 bits (160), Expect = 4e-11
Identities = 51/179 (28%), Positives = 88/179 (49%), Gaps = 4/179 (2%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
LN+ EN+I I +F+ L ++ +L L++N I+ + G F L + N +
Sbjct: 81 LNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGPANPNTLELFDNRLATIP 140
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL-DLSSIRELPE-EFISNSPLR 313
+ F L ++E+ + NN ++ F+ +P+LR L L +L + + E F S LR
Sbjct: 141 NGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLR 200
Query: 314 TLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 372
L+LA LR +P L +L L LS N ++ + P F L L+ M ++++V
Sbjct: 201 YLNLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIRV 257
Score = 59.7 bits (138), Expect = 2e-08
Identities = 54/226 (23%), Positives = 97/226 (42%), Gaps = 4/226 (1%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T L+ + + V+ + L L +L+ T+ F LEL D ++
Sbjct: 78 TRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGPANPNTLELFDNRLA 137
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK-NRIQALPAGLFASTP 239
+P+ AF+ L+ L++L + N I +I + AF + ++ L L + R+ + G F
Sbjct: 138 TIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLS 197
Query: 240 RLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI 299
L L + + R + + T L + E+ +S N ++ F L L+ L + S I
Sbjct: 198 NLRYLNLAMCNLREIPNLT--PLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQI 255
Query: 300 RELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
R + N L ++LA N L +LP + L + L +N
Sbjct: 256 RVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
Score = 50.0 bits (114), Expect = 1e-05
Identities = 35/173 (20%), Positives = 77/173 (44%), Gaps = 3/173 (1%)
Query: 102 VFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNIT-LHA 160
+F N + + AF L + ++P +P L L + ++ +
Sbjct: 131 LFDNRLATIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISE 190
Query: 161 NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVL 220
F L+YL L+ + +P+ L L++L++ N ++ I G+F+GL ++ L
Sbjct: 191 GAFEGLSNLRYLNLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKL 248
Query: 221 SLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
+ +++I+ + F + L+ + + N+ L + F L H++ I + +N
Sbjct: 249 WMIQSQIRVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
Score = 47.2 bits (107), Expect = 1e-04
Identities = 41/157 (26%), Positives = 68/157 (43%), Gaps = 4/157 (2%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N +L+L++N+IQ + F L L + RN R ++ F G + +++ +N
Sbjct: 77 NTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGPANPNTLELFDNRL 136
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLAR-NQLRVLPRSVLRGQ 333
T+ F L L+ L L + I +P + P LR L L +L + G
Sbjct: 137 ATIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGL 196
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ L L L+ + E+ P L L L+ + GN L
Sbjct: 197 SNLRYLNLAMCNLREI-PNL-TPLIKLDELDLSGNHL 231
>BC111013-1|AAI11014.1| 428|Homo sapiens immunoglobulin superfamily
containing leucine-rich repeat protein.
Length = 428
Score = 70.5 bits (165), Expect = 9e-12
Identities = 41/130 (31%), Positives = 66/130 (50%), Gaps = 1/130 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
NVT LSL+ NR+ LP G F P L +L + N R + + L H++ + +S+N+
Sbjct: 51 NVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLI 110
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
+ NL AL+ L++D + + +P + F S LR+L L N+L L T
Sbjct: 111 SDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLT 170
Query: 335 QLTSLTLSYN 344
L+ L ++ N
Sbjct: 171 ALSHLQINEN 180
Score = 57.6 bits (133), Expect = 7e-08
Identities = 37/124 (29%), Positives = 62/124 (50%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L LS ++ LP+ AF + +L+ L + NEI + AGA L ++ L L+ N I
Sbjct: 55 LSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFA 114
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
+ L L M N ++ + FR L ++ +++++N TL E F+ L AL
Sbjct: 115 WSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSH 174
Query: 292 LQLD 295
LQ++
Sbjct: 175 LQIN 178
Score = 49.6 bits (113), Expect = 2e-05
Identities = 33/93 (35%), Positives = 49/93 (52%), Gaps = 2/93 (2%)
Query: 280 EAVFSNLPA-LRTLQLDLSSIRELPEEFISNSPL-RTLSLARNQLRVLPRSVLRGQTQLT 337
E+V PA + TL L + + LPE PL ++L LA N++R + L + L
Sbjct: 42 ESVPPGFPANVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLK 101
Query: 338 SLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
SL LS+N +++ A +L AL+ MD NEL
Sbjct: 102 SLDLSHNLISDFAWSDLHNLSALQLLKMDSNEL 134
Score = 49.6 bits (113), Expect = 2e-05
Identities = 39/132 (29%), Positives = 56/132 (42%), Gaps = 1/132 (0%)
Query: 120 ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKI 179
+T L + +A +P R +P L L T+ A A+ LK L+LS I
Sbjct: 52 VTTLSL-SANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLI 110
Query: 180 TVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTP 239
+ L+ L+ L + NE+ I AFR L + L LN NR+ L G F
Sbjct: 111 SDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLT 170
Query: 240 RLLNLTMMRNSF 251
L +L + N F
Sbjct: 171 ALSHLQINENPF 182
Score = 47.2 bits (107), Expect = 1e-04
Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L++ N + + GAFR + + L L N I+ + AG AS L +L + N
Sbjct: 55 LSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFA 114
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
L +Q +K+ +N + F +L ALR+LQL+ + + L E + +PL L
Sbjct: 115 WSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEG--TFTPLTAL 172
Query: 316 S 316
S
Sbjct: 173 S 173
Score = 35.5 bits (78), Expect = 0.33
Identities = 40/168 (23%), Positives = 64/168 (38%), Gaps = 11/168 (6%)
Query: 14 ACPEQCWCTDGEELNYQCSRPSTNLIVGARPRDYVNIDCMGGELVCAEFPEIDTPATTQL 73
ACPE C C GE+ +Q + + + P N+ + L P + A ++
Sbjct: 18 ACPEPCDC--GEKYGFQIADCAYRDLESVPPGFPANVTTLS--LSANRLPGLPEGAFREV 73
Query: 74 PSL-SL----RECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNA 128
P L SL E L H + + + N I+ L L+ ++
Sbjct: 74 PLLQSLWLAHNEIRTVAAGALASLSHLKSLD--LSHNLISDFAWSDLHNLSALQLLKMDS 131
Query: 129 GAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSD 176
T +P D RSL L +LN R TL F L +L++++
Sbjct: 132 NELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQINE 179
>BC022478-1|AAH22478.1| 428|Homo sapiens immunoglobulin superfamily
containing leucine-rich repeat protein.
Length = 428
Score = 70.5 bits (165), Expect = 9e-12
Identities = 41/130 (31%), Positives = 66/130 (50%), Gaps = 1/130 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
NVT LSL+ NR+ LP G F P L +L + N R + + L H++ + +S+N+
Sbjct: 51 NVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLI 110
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
+ NL AL+ L++D + + +P + F S LR+L L N+L L T
Sbjct: 111 SDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLT 170
Query: 335 QLTSLTLSYN 344
L+ L ++ N
Sbjct: 171 ALSHLQINEN 180
Score = 57.6 bits (133), Expect = 7e-08
Identities = 37/124 (29%), Positives = 62/124 (50%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L LS ++ LP+ AF + +L+ L + NEI + AGA L ++ L L+ N I
Sbjct: 55 LSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFA 114
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
+ L L M N ++ + FR L ++ +++++N TL E F+ L AL
Sbjct: 115 WSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSH 174
Query: 292 LQLD 295
LQ++
Sbjct: 175 LQIN 178
Score = 49.6 bits (113), Expect = 2e-05
Identities = 33/93 (35%), Positives = 49/93 (52%), Gaps = 2/93 (2%)
Query: 280 EAVFSNLPA-LRTLQLDLSSIRELPEEFISNSPL-RTLSLARNQLRVLPRSVLRGQTQLT 337
E+V PA + TL L + + LPE PL ++L LA N++R + L + L
Sbjct: 42 ESVPPGFPANVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLK 101
Query: 338 SLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
SL LS+N +++ A +L AL+ MD NEL
Sbjct: 102 SLDLSHNLISDFAWSDLHNLSALQLLKMDSNEL 134
Score = 49.6 bits (113), Expect = 2e-05
Identities = 39/132 (29%), Positives = 56/132 (42%), Gaps = 1/132 (0%)
Query: 120 ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKI 179
+T L + +A +P R +P L L T+ A A+ LK L+LS I
Sbjct: 52 VTTLSL-SANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLI 110
Query: 180 TVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTP 239
+ L+ L+ L + NE+ I AFR L + L LN NR+ L G F
Sbjct: 111 SDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLT 170
Query: 240 RLLNLTMMRNSF 251
L +L + N F
Sbjct: 171 ALSHLQINENPF 182
Score = 47.2 bits (107), Expect = 1e-04
Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L++ N + + GAFR + + L L N I+ + AG AS L +L + N
Sbjct: 55 LSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFA 114
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
L +Q +K+ +N + F +L ALR+LQL+ + + L E + +PL L
Sbjct: 115 WSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEG--TFTPLTAL 172
Query: 316 S 316
S
Sbjct: 173 S 173
Score = 35.5 bits (78), Expect = 0.33
Identities = 40/168 (23%), Positives = 64/168 (38%), Gaps = 11/168 (6%)
Query: 14 ACPEQCWCTDGEELNYQCSRPSTNLIVGARPRDYVNIDCMGGELVCAEFPEIDTPATTQL 73
ACPE C C GE+ +Q + + + P N+ + L P + A ++
Sbjct: 18 ACPEPCDC--GEKYGFQIADCAYRDLESVPPGFPANVTTLS--LSANRLPGLPEGAFREV 73
Query: 74 PSL-SL----RECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNA 128
P L SL E L H + + + N I+ L L+ ++
Sbjct: 74 PLLQSLWLAHNEIRTVAAGALASLSHLKSLD--LSHNLISDFAWSDLHNLSALQLLKMDS 131
Query: 129 GAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSD 176
T +P D RSL L +LN R TL F L +L++++
Sbjct: 132 NELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQINE 179
>AY358871-1|AAQ89230.1| 428|Homo sapiens ISLR protein.
Length = 428
Score = 70.5 bits (165), Expect = 9e-12
Identities = 41/130 (31%), Positives = 66/130 (50%), Gaps = 1/130 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
NVT LSL+ NR+ LP G F P L +L + N R + + L H++ + +S+N+
Sbjct: 51 NVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLI 110
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
+ NL AL+ L++D + + +P + F S LR+L L N+L L T
Sbjct: 111 SDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLT 170
Query: 335 QLTSLTLSYN 344
L+ L ++ N
Sbjct: 171 ALSHLQINEN 180
Score = 57.6 bits (133), Expect = 7e-08
Identities = 37/124 (29%), Positives = 62/124 (50%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L LS ++ LP+ AF + +L+ L + NEI + AGA L ++ L L+ N I
Sbjct: 55 LSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFA 114
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
+ L L M N ++ + FR L ++ +++++N TL E F+ L AL
Sbjct: 115 WSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSH 174
Query: 292 LQLD 295
LQ++
Sbjct: 175 LQIN 178
Score = 49.6 bits (113), Expect = 2e-05
Identities = 33/93 (35%), Positives = 49/93 (52%), Gaps = 2/93 (2%)
Query: 280 EAVFSNLPA-LRTLQLDLSSIRELPEEFISNSPL-RTLSLARNQLRVLPRSVLRGQTQLT 337
E+V PA + TL L + + LPE PL ++L LA N++R + L + L
Sbjct: 42 ESVPPGFPANVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLK 101
Query: 338 SLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
SL LS+N +++ A +L AL+ MD NEL
Sbjct: 102 SLDLSHNLISDFAWSDLHNLSALQLLKMDSNEL 134
Score = 49.6 bits (113), Expect = 2e-05
Identities = 39/132 (29%), Positives = 56/132 (42%), Gaps = 1/132 (0%)
Query: 120 ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKI 179
+T L + +A +P R +P L L T+ A A+ LK L+LS I
Sbjct: 52 VTTLSL-SANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLI 110
Query: 180 TVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTP 239
+ L+ L+ L + NE+ I AFR L + L LN NR+ L G F
Sbjct: 111 SDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLT 170
Query: 240 RLLNLTMMRNSF 251
L +L + N F
Sbjct: 171 ALSHLQINENPF 182
Score = 47.2 bits (107), Expect = 1e-04
Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L++ N + + GAFR + + L L N I+ + AG AS L +L + N
Sbjct: 55 LSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFA 114
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
L +Q +K+ +N + F +L ALR+LQL+ + + L E + +PL L
Sbjct: 115 WSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEG--TFTPLTAL 172
Query: 316 S 316
S
Sbjct: 173 S 173
Score = 35.5 bits (78), Expect = 0.33
Identities = 40/168 (23%), Positives = 64/168 (38%), Gaps = 11/168 (6%)
Query: 14 ACPEQCWCTDGEELNYQCSRPSTNLIVGARPRDYVNIDCMGGELVCAEFPEIDTPATTQL 73
ACPE C C GE+ +Q + + + P N+ + L P + A ++
Sbjct: 18 ACPEPCDC--GEKYGFQIADCAYRDLESVPPGFPANVTTLS--LSANRLPGLPEGAFREV 73
Query: 74 PSL-SL----RECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNA 128
P L SL E L H + + + N I+ L L+ ++
Sbjct: 74 PLLQSLWLAHNEIRTVAAGALASLSHLKSLD--LSHNLISDFAWSDLHNLSALQLLKMDS 131
Query: 129 GAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSD 176
T +P D RSL L +LN R TL F L +L++++
Sbjct: 132 NELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQINE 179
>AK223267-1|BAD96987.1| 428|Homo sapiens immunoglobulin superfamily
containing leucine-rich repeat variant protein.
Length = 428
Score = 70.5 bits (165), Expect = 9e-12
Identities = 41/130 (31%), Positives = 66/130 (50%), Gaps = 1/130 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
NVT LSL+ NR+ LP G F P L +L + N R + + L H++ + +S+N+
Sbjct: 51 NVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLI 110
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
+ NL AL+ L++D + + +P + F S LR+L L N+L L T
Sbjct: 111 SDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLT 170
Query: 335 QLTSLTLSYN 344
L+ L ++ N
Sbjct: 171 ALSHLQINEN 180
Score = 57.6 bits (133), Expect = 7e-08
Identities = 37/124 (29%), Positives = 62/124 (50%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L LS ++ LP+ AF + +L+ L + NEI + AGA L ++ L L+ N I
Sbjct: 55 LSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFA 114
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
+ L L M N ++ + FR L ++ +++++N TL E F+ L AL
Sbjct: 115 WSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSH 174
Query: 292 LQLD 295
LQ++
Sbjct: 175 LQIN 178
Score = 49.6 bits (113), Expect = 2e-05
Identities = 33/93 (35%), Positives = 49/93 (52%), Gaps = 2/93 (2%)
Query: 280 EAVFSNLPA-LRTLQLDLSSIRELPEEFISNSPL-RTLSLARNQLRVLPRSVLRGQTQLT 337
E+V PA + TL L + + LPE PL ++L LA N++R + L + L
Sbjct: 42 ESVPPGFPANVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLK 101
Query: 338 SLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
SL LS+N +++ A +L AL+ MD NEL
Sbjct: 102 SLDLSHNLISDFAWSDLHNLSALQLLKMDSNEL 134
Score = 49.6 bits (113), Expect = 2e-05
Identities = 39/132 (29%), Positives = 56/132 (42%), Gaps = 1/132 (0%)
Query: 120 ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKI 179
+T L + +A +P R +P L L T+ A A+ LK L+LS I
Sbjct: 52 VTTLSL-SANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLI 110
Query: 180 TVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTP 239
+ L+ L+ L + NE+ I AFR L + L LN NR+ L G F
Sbjct: 111 SDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLT 170
Query: 240 RLLNLTMMRNSF 251
L +L + N F
Sbjct: 171 ALSHLQINENPF 182
Score = 47.2 bits (107), Expect = 1e-04
Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L++ N + + GAFR + + L L N I+ + AG AS L +L + N
Sbjct: 55 LSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFA 114
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
L +Q +K+ +N + F +L ALR+LQL+ + + L E + +PL L
Sbjct: 115 WSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEG--TFTPLTAL 172
Query: 316 S 316
S
Sbjct: 173 S 173
Score = 35.5 bits (78), Expect = 0.33
Identities = 40/168 (23%), Positives = 64/168 (38%), Gaps = 11/168 (6%)
Query: 14 ACPEQCWCTDGEELNYQCSRPSTNLIVGARPRDYVNIDCMGGELVCAEFPEIDTPATTQL 73
ACPE C C GE+ +Q + + + P N+ + L P + A ++
Sbjct: 18 ACPEPCDC--GEKYGFQIADCAYRDLESVPPGFPANVTTLS--LSANRLPGLPEGAFREV 73
Query: 74 PSL-SL----RECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNA 128
P L SL E L H + + + N I+ L L+ ++
Sbjct: 74 PLLQSLWLAHNEIRTVAAGALASLSHLKSLD--LSHNLISDFAWSDLHNLSALQLLKMDS 131
Query: 129 GAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSD 176
T +P D RSL L +LN R TL F L +L++++
Sbjct: 132 NELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQINE 179
>AB024537-1|BAA85971.1| 428|Homo sapiens ISLR protein.
Length = 428
Score = 70.5 bits (165), Expect = 9e-12
Identities = 41/130 (31%), Positives = 66/130 (50%), Gaps = 1/130 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
NVT LSL+ NR+ LP G F P L +L + N R + + L H++ + +S+N+
Sbjct: 51 NVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLI 110
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
+ NL AL+ L++D + + +P + F S LR+L L N+L L T
Sbjct: 111 SDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLT 170
Query: 335 QLTSLTLSYN 344
L+ L ++ N
Sbjct: 171 ALSHLQINEN 180
Score = 57.6 bits (133), Expect = 7e-08
Identities = 37/124 (29%), Positives = 62/124 (50%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L LS ++ LP+ AF + +L+ L + NEI + AGA L ++ L L+ N I
Sbjct: 55 LSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFA 114
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
+ L L M N ++ + FR L ++ +++++N TL E F+ L AL
Sbjct: 115 WSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSH 174
Query: 292 LQLD 295
LQ++
Sbjct: 175 LQIN 178
Score = 49.6 bits (113), Expect = 2e-05
Identities = 33/93 (35%), Positives = 49/93 (52%), Gaps = 2/93 (2%)
Query: 280 EAVFSNLPA-LRTLQLDLSSIRELPEEFISNSPL-RTLSLARNQLRVLPRSVLRGQTQLT 337
E+V PA + TL L + + LPE PL ++L LA N++R + L + L
Sbjct: 42 ESVPPGFPANVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLK 101
Query: 338 SLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
SL LS+N +++ A +L AL+ MD NEL
Sbjct: 102 SLDLSHNLISDFAWSDLHNLSALQLLKMDSNEL 134
Score = 49.6 bits (113), Expect = 2e-05
Identities = 39/132 (29%), Positives = 56/132 (42%), Gaps = 1/132 (0%)
Query: 120 ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKI 179
+T L + +A +P R +P L L T+ A A+ LK L+LS I
Sbjct: 52 VTTLSL-SANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLI 110
Query: 180 TVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTP 239
+ L+ L+ L + NE+ I AFR L + L LN NR+ L G F
Sbjct: 111 SDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLT 170
Query: 240 RLLNLTMMRNSF 251
L +L + N F
Sbjct: 171 ALSHLQINENPF 182
Score = 47.2 bits (107), Expect = 1e-04
Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L++ N + + GAFR + + L L N I+ + AG AS L +L + N
Sbjct: 55 LSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFA 114
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
L +Q +K+ +N + F +L ALR+LQL+ + + L E + +PL L
Sbjct: 115 WSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEG--TFTPLTAL 172
Query: 316 S 316
S
Sbjct: 173 S 173
Score = 35.5 bits (78), Expect = 0.33
Identities = 40/168 (23%), Positives = 64/168 (38%), Gaps = 11/168 (6%)
Query: 14 ACPEQCWCTDGEELNYQCSRPSTNLIVGARPRDYVNIDCMGGELVCAEFPEIDTPATTQL 73
ACPE C C GE+ +Q + + + P N+ + L P + A ++
Sbjct: 18 ACPEPCDC--GEKYGFQIADCAYRDLESVPPGFPANVTTLS--LSANRLPGLPEGAFREV 73
Query: 74 PSL-SL----RECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNA 128
P L SL E L H + + + N I+ L L+ ++
Sbjct: 74 PLLQSLWLAHNEIRTVAAGALASLSHLKSLD--LSHNLISDFAWSDLHNLSALQLLKMDS 131
Query: 129 GAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSD 176
T +P D RSL L +LN R TL F L +L++++
Sbjct: 132 NELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQINE 179
>AB024536-1|BAA85970.1| 428|Homo sapiens ISLR protein.
Length = 428
Score = 70.5 bits (165), Expect = 9e-12
Identities = 41/130 (31%), Positives = 66/130 (50%), Gaps = 1/130 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
NVT LSL+ NR+ LP G F P L +L + N R + + L H++ + +S+N+
Sbjct: 51 NVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLI 110
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
+ NL AL+ L++D + + +P + F S LR+L L N+L L T
Sbjct: 111 SDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLT 170
Query: 335 QLTSLTLSYN 344
L+ L ++ N
Sbjct: 171 ALSHLQINEN 180
Score = 57.6 bits (133), Expect = 7e-08
Identities = 37/124 (29%), Positives = 62/124 (50%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L LS ++ LP+ AF + +L+ L + NEI + AGA L ++ L L+ N I
Sbjct: 55 LSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFA 114
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
+ L L M N ++ + FR L ++ +++++N TL E F+ L AL
Sbjct: 115 WSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSH 174
Query: 292 LQLD 295
LQ++
Sbjct: 175 LQIN 178
Score = 49.6 bits (113), Expect = 2e-05
Identities = 33/93 (35%), Positives = 49/93 (52%), Gaps = 2/93 (2%)
Query: 280 EAVFSNLPA-LRTLQLDLSSIRELPEEFISNSPL-RTLSLARNQLRVLPRSVLRGQTQLT 337
E+V PA + TL L + + LPE PL ++L LA N++R + L + L
Sbjct: 42 ESVPPGFPANVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLK 101
Query: 338 SLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
SL LS+N +++ A +L AL+ MD NEL
Sbjct: 102 SLDLSHNLISDFAWSDLHNLSALQLLKMDSNEL 134
Score = 49.6 bits (113), Expect = 2e-05
Identities = 39/132 (29%), Positives = 56/132 (42%), Gaps = 1/132 (0%)
Query: 120 ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKI 179
+T L + +A +P R +P L L T+ A A+ LK L+LS I
Sbjct: 52 VTTLSL-SANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLI 110
Query: 180 TVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTP 239
+ L+ L+ L + NE+ I AFR L + L LN NR+ L G F
Sbjct: 111 SDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLT 170
Query: 240 RLLNLTMMRNSF 251
L +L + N F
Sbjct: 171 ALSHLQINENPF 182
Score = 47.2 bits (107), Expect = 1e-04
Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L++ N + + GAFR + + L L N I+ + AG AS L +L + N
Sbjct: 55 LSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFA 114
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
L +Q +K+ +N + F +L ALR+LQL+ + + L E + +PL L
Sbjct: 115 WSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEG--TFTPLTAL 172
Query: 316 S 316
S
Sbjct: 173 S 173
Score = 35.5 bits (78), Expect = 0.33
Identities = 40/168 (23%), Positives = 64/168 (38%), Gaps = 11/168 (6%)
Query: 14 ACPEQCWCTDGEELNYQCSRPSTNLIVGARPRDYVNIDCMGGELVCAEFPEIDTPATTQL 73
ACPE C C GE+ +Q + + + P N+ + L P + A ++
Sbjct: 18 ACPEPCDC--GEKYGFQIADCAYRDLESVPPGFPANVTTLS--LSANRLPGLPEGAFREV 73
Query: 74 PSL-SL----RECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNA 128
P L SL E L H + + + N I+ L L+ ++
Sbjct: 74 PLLQSLWLAHNEIRTVAAGALASLSHLKSLD--LSHNLISDFAWSDLHNLSALQLLKMDS 131
Query: 129 GAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSD 176
T +P D RSL L +LN R TL F L +L++++
Sbjct: 132 NELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQINE 179
>AB003184-1|BAA22848.1| 428|Homo sapiens ISLR protein.
Length = 428
Score = 70.5 bits (165), Expect = 9e-12
Identities = 41/130 (31%), Positives = 66/130 (50%), Gaps = 1/130 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
NVT LSL+ NR+ LP G F P L +L + N R + + L H++ + +S+N+
Sbjct: 51 NVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLI 110
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
+ NL AL+ L++D + + +P + F S LR+L L N+L L T
Sbjct: 111 SDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLT 170
Query: 335 QLTSLTLSYN 344
L+ L ++ N
Sbjct: 171 ALSHLQINEN 180
Score = 57.6 bits (133), Expect = 7e-08
Identities = 37/124 (29%), Positives = 62/124 (50%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L LS ++ LP+ AF + +L+ L + NEI + AGA L ++ L L+ N I
Sbjct: 55 LSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFA 114
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
+ L L M N ++ + FR L ++ +++++N TL E F+ L AL
Sbjct: 115 WSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSH 174
Query: 292 LQLD 295
LQ++
Sbjct: 175 LQIN 178
Score = 49.6 bits (113), Expect = 2e-05
Identities = 33/93 (35%), Positives = 49/93 (52%), Gaps = 2/93 (2%)
Query: 280 EAVFSNLPA-LRTLQLDLSSIRELPEEFISNSPL-RTLSLARNQLRVLPRSVLRGQTQLT 337
E+V PA + TL L + + LPE PL ++L LA N++R + L + L
Sbjct: 42 ESVPPGFPANVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLK 101
Query: 338 SLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
SL LS+N +++ A +L AL+ MD NEL
Sbjct: 102 SLDLSHNLISDFAWSDLHNLSALQLLKMDSNEL 134
Score = 49.6 bits (113), Expect = 2e-05
Identities = 39/132 (29%), Positives = 56/132 (42%), Gaps = 1/132 (0%)
Query: 120 ITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKI 179
+T L + +A +P R +P L L T+ A A+ LK L+LS I
Sbjct: 52 VTTLSL-SANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLI 110
Query: 180 TVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTP 239
+ L+ L+ L + NE+ I AFR L + L LN NR+ L G F
Sbjct: 111 SDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLT 170
Query: 240 RLLNLTMMRNSF 251
L +L + N F
Sbjct: 171 ALSHLQINENPF 182
Score = 47.2 bits (107), Expect = 1e-04
Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
L++ N + + GAFR + + L L N I+ + AG AS L +L + N
Sbjct: 55 LSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFA 114
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
L +Q +K+ +N + F +L ALR+LQL+ + + L E + +PL L
Sbjct: 115 WSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEG--TFTPLTAL 172
Query: 316 S 316
S
Sbjct: 173 S 173
Score = 35.5 bits (78), Expect = 0.33
Identities = 40/168 (23%), Positives = 64/168 (38%), Gaps = 11/168 (6%)
Query: 14 ACPEQCWCTDGEELNYQCSRPSTNLIVGARPRDYVNIDCMGGELVCAEFPEIDTPATTQL 73
ACPE C C GE+ +Q + + + P N+ + L P + A ++
Sbjct: 18 ACPEPCDC--GEKYGFQIADCAYRDLESVPPGFPANVTTLS--LSANRLPGLPEGAFREV 73
Query: 74 PSL-SL----RECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNA 128
P L SL E L H + + + N I+ L L+ ++
Sbjct: 74 PLLQSLWLAHNEIRTVAAGALASLSHLKSLD--LSHNLISDFAWSDLHNLSALQLLKMDS 131
Query: 129 GAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSD 176
T +P D RSL L +LN R TL F L +L++++
Sbjct: 132 NELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQINE 179
>BC111745-1|AAI11746.1| 653|Homo sapiens leucine rich repeat
containing 4 protein.
Length = 653
Score = 70.1 bits (164), Expect = 1e-11
Identities = 57/215 (26%), Positives = 94/215 (43%), Gaps = 24/215 (11%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+YL L + I ++ D F L+ LE L + N I I GAF GL ++ L L N +
Sbjct: 78 RYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTV 137
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPA 288
+P+G F +L L + N + S F + + + + L + E F L
Sbjct: 138 IPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFN 197
Query: 289 LRTLQLDLSSIRELP--------EE---------------FISNSPLRTLSLARNQLRVL 325
L+ L L + +I+++P EE F S L+ L + +Q+ ++
Sbjct: 198 LKYLNLGMCNIKDMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLI 257
Query: 326 PRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 360
R+ G L L L++N ++ L +LF LR L
Sbjct: 258 ERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYL 292
Score = 66.5 bits (155), Expect = 2e-10
Identities = 51/172 (29%), Positives = 83/172 (48%), Gaps = 12/172 (6%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
LN+ EN I I A FR LH++ VL L +N I+ + G F L L + N +
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP---- 311
S F L ++E+ + NN ++ F+ +P+L ++LDL +++L E+IS
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSL--MRLDLGELKKL--EYISEGAFEGL 195
Query: 312 --LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALE 361
L+ L+L ++ +P L L L +S N E+ P F L +L+
Sbjct: 196 FNLKYLNLGMCNIKDMPN--LTPLVGLEELEMSGNHFPEIRPGSFHGLSSLK 245
Score = 59.3 bits (137), Expect = 2e-08
Identities = 56/236 (23%), Positives = 100/236 (42%), Gaps = 5/236 (2%)
Query: 81 CSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLR 140
C+ LS + Q + + + +N I + AD F+ L ++ + + V
Sbjct: 61 CTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFN 120
Query: 141 SLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
L L L + + F L+ L L + I +P AF + L +L++ E
Sbjct: 121 GLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGE 180
Query: 201 -NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
++ I+ GAF GL N+ L+L I+ +P L L M N F + +F
Sbjct: 181 LKKLEYISEGAFEGLFNLKYLNLGMCNIKDMPN--LTPLVGLEELEMSGNHFPEIRPGSF 238
Query: 260 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
GL ++++ + N+ ++ F L +L L L +++ LP + +PLR L
Sbjct: 239 HGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLF--TPLRYL 292
Score = 49.6 bits (113), Expect = 2e-05
Identities = 43/155 (27%), Positives = 63/155 (40%), Gaps = 4/155 (2%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L+L +N IQ + A F L L + RNS R ++ F GL + +++ +N
Sbjct: 76 NTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWL 135
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLAR-NQLRVLPRSVLRGQ 333
+ F L LR L L + I +P + P L L L +L + G
Sbjct: 136 TVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGL 195
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
L L L + ++ P L L LE M GN
Sbjct: 196 FNLKYLNLGMCNIKDM-PNL-TPLVGLEELEMSGN 228
Score = 48.0 bits (109), Expect = 6e-05
Identities = 54/263 (20%), Positives = 105/263 (39%), Gaps = 12/263 (4%)
Query: 15 CPEQCWCTDGEELNYQCSRPSTNLIVGARPRD--YVNIDCMGGELVCAE-FPEIDTPATT 71
CP C C++ + C+R + + P + Y+N+ +++ A+ F +
Sbjct: 46 CPSVCSCSN-QFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRHLHHLEVL 104
Query: 72 QLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQ 131
QL S+R+ + + L E +F N + + + AF+ L +
Sbjct: 105 QLGRNSIRQIEVGAFNGLASLNTLE-----LFDNWLTVIPSGAFEYLSKLRELWLRNNPI 159
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGL 190
++P +P L L + + + F LKYL L I +P+ L
Sbjct: 160 ESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIKDMPN--LTPL 217
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS 250
LE+L + N I G+F GL ++ L + +++ + F L+ L + N+
Sbjct: 218 VGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNN 277
Query: 251 FRYLDSETFRGLDHIQEIKISNN 273
L + F L ++ E+ + +N
Sbjct: 278 LSSLPHDLFTPLRYLVELHLHHN 300
>BC111561-1|AAI11562.1| 653|Homo sapiens leucine rich repeat
containing 4 protein.
Length = 653
Score = 70.1 bits (164), Expect = 1e-11
Identities = 57/215 (26%), Positives = 94/215 (43%), Gaps = 24/215 (11%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+YL L + I ++ D F L+ LE L + N I I GAF GL ++ L L N +
Sbjct: 78 RYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTV 137
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPA 288
+P+G F +L L + N + S F + + + + L + E F L
Sbjct: 138 IPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFN 197
Query: 289 LRTLQLDLSSIRELP--------EE---------------FISNSPLRTLSLARNQLRVL 325
L+ L L + +I+++P EE F S L+ L + +Q+ ++
Sbjct: 198 LKYLNLGMCNIKDMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLI 257
Query: 326 PRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 360
R+ G L L L++N ++ L +LF LR L
Sbjct: 258 ERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYL 292
Score = 66.5 bits (155), Expect = 2e-10
Identities = 51/172 (29%), Positives = 83/172 (48%), Gaps = 12/172 (6%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
LN+ EN I I A FR LH++ VL L +N I+ + G F L L + N +
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP---- 311
S F L ++E+ + NN ++ F+ +P+L ++LDL +++L E+IS
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSL--MRLDLGELKKL--EYISEGAFEGL 195
Query: 312 --LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALE 361
L+ L+L ++ +P L L L +S N E+ P F L +L+
Sbjct: 196 FNLKYLNLGMCNIKDMPN--LTPLVGLEELEMSGNHFPEIRPGSFHGLSSLK 245
Score = 59.3 bits (137), Expect = 2e-08
Identities = 56/236 (23%), Positives = 100/236 (42%), Gaps = 5/236 (2%)
Query: 81 CSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLR 140
C+ LS + Q + + + +N I + AD F+ L ++ + + V
Sbjct: 61 CTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFN 120
Query: 141 SLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
L L L + + F L+ L L + I +P AF + L +L++ E
Sbjct: 121 GLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGE 180
Query: 201 -NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
++ I+ GAF GL N+ L+L I+ +P L L M N F + +F
Sbjct: 181 LKKLEYISEGAFEGLFNLKYLNLGMCNIKDMPN--LTPLVGLEELEMSGNHFPEIRPGSF 238
Query: 260 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
GL ++++ + N+ ++ F L +L L L +++ LP + +PLR L
Sbjct: 239 HGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLF--TPLRYL 292
Score = 49.6 bits (113), Expect = 2e-05
Identities = 43/155 (27%), Positives = 63/155 (40%), Gaps = 4/155 (2%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L+L +N IQ + A F L L + RNS R ++ F GL + +++ +N
Sbjct: 76 NTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWL 135
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLAR-NQLRVLPRSVLRGQ 333
+ F L LR L L + I +P + P L L L +L + G
Sbjct: 136 TVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGL 195
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
L L L + ++ P L L LE M GN
Sbjct: 196 FNLKYLNLGMCNIKDM-PNL-TPLVGLEELEMSGN 228
Score = 48.0 bits (109), Expect = 6e-05
Identities = 54/263 (20%), Positives = 105/263 (39%), Gaps = 12/263 (4%)
Query: 15 CPEQCWCTDGEELNYQCSRPSTNLIVGARPRD--YVNIDCMGGELVCAE-FPEIDTPATT 71
CP C C++ + C+R + + P + Y+N+ +++ A+ F +
Sbjct: 46 CPSVCSCSN-QFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRHLHHLEVL 104
Query: 72 QLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQ 131
QL S+R+ + + L E +F N + + + AF+ L +
Sbjct: 105 QLGRNSIRQIEVGAFNGLASLNTLE-----LFDNWLTVIPSGAFEYLSKLRELWLRNNPI 159
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGL 190
++P +P L L + + + F LKYL L I +P+ L
Sbjct: 160 ESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIKDMPN--LTPL 217
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS 250
LE+L + N I G+F GL ++ L + +++ + F L+ L + N+
Sbjct: 218 VGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNN 277
Query: 251 FRYLDSETFRGLDHIQEIKISNN 273
L + F L ++ E+ + +N
Sbjct: 278 LSSLPHDLFTPLRYLVELHLHHN 300
>AY358307-1|AAQ88674.1| 653|Homo sapiens NAG14 protein.
Length = 653
Score = 70.1 bits (164), Expect = 1e-11
Identities = 57/215 (26%), Positives = 94/215 (43%), Gaps = 24/215 (11%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+YL L + I ++ D F L+ LE L + N I I GAF GL ++ L L N +
Sbjct: 78 RYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTV 137
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPA 288
+P+G F +L L + N + S F + + + + L + E F L
Sbjct: 138 IPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFN 197
Query: 289 LRTLQLDLSSIRELP--------EE---------------FISNSPLRTLSLARNQLRVL 325
L+ L L + +I+++P EE F S L+ L + +Q+ ++
Sbjct: 198 LKYLNLGMCNIKDMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLI 257
Query: 326 PRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 360
R+ G L L L++N ++ L +LF LR L
Sbjct: 258 ERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYL 292
Score = 66.5 bits (155), Expect = 2e-10
Identities = 51/172 (29%), Positives = 83/172 (48%), Gaps = 12/172 (6%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
LN+ EN I I A FR LH++ VL L +N I+ + G F L L + N +
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP---- 311
S F L ++E+ + NN ++ F+ +P+L ++LDL +++L E+IS
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSL--MRLDLGELKKL--EYISEGAFEGL 195
Query: 312 --LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALE 361
L+ L+L ++ +P L L L +S N E+ P F L +L+
Sbjct: 196 FNLKYLNLGMCNIKDMPN--LTPLVGLEELEMSGNHFPEIRPGSFHGLSSLK 245
Score = 59.3 bits (137), Expect = 2e-08
Identities = 56/236 (23%), Positives = 100/236 (42%), Gaps = 5/236 (2%)
Query: 81 CSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLR 140
C+ LS + Q + + + +N I + AD F+ L ++ + + V
Sbjct: 61 CTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFN 120
Query: 141 SLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
L L L + + F L+ L L + I +P AF + L +L++ E
Sbjct: 121 GLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGE 180
Query: 201 -NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
++ I+ GAF GL N+ L+L I+ +P L L M N F + +F
Sbjct: 181 LKKLEYISEGAFEGLFNLKYLNLGMCNIKDMPN--LTPLVGLEELEMSGNHFPEIRPGSF 238
Query: 260 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
GL ++++ + N+ ++ F L +L L L +++ LP + +PLR L
Sbjct: 239 HGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLF--TPLRYL 292
Score = 49.6 bits (113), Expect = 2e-05
Identities = 43/155 (27%), Positives = 63/155 (40%), Gaps = 4/155 (2%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L+L +N IQ + A F L L + RNS R ++ F GL + +++ +N
Sbjct: 76 NTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWL 135
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLAR-NQLRVLPRSVLRGQ 333
+ F L LR L L + I +P + P L L L +L + G
Sbjct: 136 TVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGL 195
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
L L L + ++ P L L LE M GN
Sbjct: 196 FNLKYLNLGMCNIKDM-PNL-TPLVGLEELEMSGN 228
Score = 48.0 bits (109), Expect = 6e-05
Identities = 54/263 (20%), Positives = 105/263 (39%), Gaps = 12/263 (4%)
Query: 15 CPEQCWCTDGEELNYQCSRPSTNLIVGARPRD--YVNIDCMGGELVCAE-FPEIDTPATT 71
CP C C++ + C+R + + P + Y+N+ +++ A+ F +
Sbjct: 46 CPSVCSCSN-QFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRHLHHLEVL 104
Query: 72 QLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQ 131
QL S+R+ + + L E +F N + + + AF+ L +
Sbjct: 105 QLGRNSIRQIEVGAFNGLASLNTLE-----LFDNWLTVIPSGAFEYLSKLRELWLRNNPI 159
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGL 190
++P +P L L + + + F LKYL L I +P+ L
Sbjct: 160 ESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIKDMPN--LTPL 217
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS 250
LE+L + N I G+F GL ++ L + +++ + F L+ L + N+
Sbjct: 218 VGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNN 277
Query: 251 FRYLDSETFRGLDHIQEIKISNN 273
L + F L ++ E+ + +N
Sbjct: 278 LSSLPHDLFTPLRYLVELHLHHN 300
>AK172834-1|BAD18799.1| 459|Homo sapiens protein ( Homo sapiens
cDNA FLJ23995 fis, clone HRC11525. ).
Length = 459
Score = 70.1 bits (164), Expect = 1e-11
Identities = 52/183 (28%), Positives = 88/183 (48%), Gaps = 2/183 (1%)
Query: 114 AFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLE 173
AF GL + T VP + L L L L + F LK+LE
Sbjct: 25 AFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLE 84
Query: 174 LSD-AKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
+ + ++P ++ GLN L L+V ++ + AF+ L +T L+L+ N I + A
Sbjct: 85 IDYWPLLDMMPANSLYGLN-LTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEA 143
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTL 292
G+F+ RL L ++ R ++ +F+GL ++ + +S N+ TL+E VFS+ AL L
Sbjct: 144 GMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVL 203
Query: 293 QLD 295
++
Sbjct: 204 SIN 206
Score = 57.6 bits (133), Expect = 7e-08
Identities = 35/119 (29%), Positives = 60/119 (50%), Gaps = 1/119 (0%)
Query: 107 INPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANT 166
++ + A++ GL +T+L + N +TVP + L LTH L+ T+ A MF++
Sbjct: 91 LDMMPANSLYGLNLTSLSVTNTNL-STVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDL 149
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
L+ L + A++ + +F GL L LNV +N + + F + VLS+N N
Sbjct: 150 IRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNN 208
Score = 54.4 bits (125), Expect = 7e-07
Identities = 55/213 (25%), Positives = 92/213 (43%), Gaps = 7/213 (3%)
Query: 162 MFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLS 221
MF + LK LE+ D + + AF GL LEQL + + + + A L ++ L
Sbjct: 1 MFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLH 60
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD---SETFRGLDHIQEIKISNNVPLTL 278
L I +P F L +L + + + LD + + GL+ + + ++N T+
Sbjct: 61 LKHLNINNMPVYAFKRLFHLKHLEI--DYWPLLDMMPANSLYGLN-LTSLSVTNTNLSTV 117
Query: 279 KEAVFSNLPALRTLQLDLSSIRELPEEFISNS-PLRTLSLARNQLRVLPRSVLRGQTQLT 337
F +L L L L + I + S+ L+ L + QLR + +G L
Sbjct: 118 PFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLR 177
Query: 338 SLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L +S N + L +F+ RALE ++ N L
Sbjct: 178 VLNVSQNLLETLEENVFSSPRALEVLSINNNPL 210
Score = 50.8 bits (116), Expect = 8e-06
Identities = 47/186 (25%), Positives = 86/186 (46%), Gaps = 25/186 (13%)
Query: 187 FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTM 246
F L+ L+ L V +N++ I+ AF GL ++ L+L K + A+P + L++L
Sbjct: 2 FQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISL-- 59
Query: 247 MRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRE-LPEE 305
H++ + I NN+P+ F L L+ L++D + + +P
Sbjct: 60 -----------------HLKHLNI-NNMPV----YAFKRLFHLKHLEIDYWPLLDMMPAN 97
Query: 306 FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVM 365
+ L +LS+ L +P + LT L LSYN ++ + +F+DL L+ +
Sbjct: 98 SLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHI 157
Query: 366 DGNELQ 371
G +L+
Sbjct: 158 VGAQLR 163
>AK172751-1|BAD18737.1| 653|Homo sapiens protein ( Homo sapiens
cDNA FLJ23912 fis, clone CAE04210, highly similar to
Homo sapiens leucine rich repeat containing 4 (LRRC4).
).
Length = 653
Score = 70.1 bits (164), Expect = 1e-11
Identities = 57/215 (26%), Positives = 94/215 (43%), Gaps = 24/215 (11%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+YL L + I ++ D F L+ LE L + N I I GAF GL ++ L L N +
Sbjct: 78 RYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTV 137
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPA 288
+P+G F +L L + N + S F + + + + L + E F L
Sbjct: 138 IPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFN 197
Query: 289 LRTLQLDLSSIRELP--------EE---------------FISNSPLRTLSLARNQLRVL 325
L+ L L + +I+++P EE F S L+ L + +Q+ ++
Sbjct: 198 LKYLNLGMCNIKDMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLI 257
Query: 326 PRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 360
R+ G L L L++N ++ L +LF LR L
Sbjct: 258 ERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYL 292
Score = 66.5 bits (155), Expect = 2e-10
Identities = 51/172 (29%), Positives = 83/172 (48%), Gaps = 12/172 (6%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
LN+ EN I I A FR LH++ VL L +N I+ + G F L L + N +
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP---- 311
S F L ++E+ + NN ++ F+ +P+L ++LDL +++L E+IS
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSL--MRLDLGELKKL--EYISEGAFEGL 195
Query: 312 --LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALE 361
L+ L+L ++ +P L L L +S N E+ P F L +L+
Sbjct: 196 FNLKYLNLGMCNIKDMPN--LTPLVGLEELEMSGNHFPEIRPGSFHGLSSLK 245
Score = 52.4 bits (120), Expect = 3e-06
Identities = 52/213 (24%), Positives = 90/213 (42%), Gaps = 4/213 (1%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
+ D R L L +L + F L LEL D +TV+P AF L+ L
Sbjct: 90 IQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKL 149
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNK-NRIQALPAGLFASTPRLLNLTMMRNSFR 252
+L + N I +I + AF + ++ L L + +++ + G F L L + + +
Sbjct: 150 RELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIK 209
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSP 311
D L ++E+++S N ++ F L +L+ L + S + + F +
Sbjct: 210 --DMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLAS 267
Query: 312 LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
L L+LA N L LP + L L L ++
Sbjct: 268 LVELNLAHNNLSSLPHDLFTPLRYLVELHLHHD 300
Score = 49.6 bits (113), Expect = 2e-05
Identities = 43/155 (27%), Positives = 63/155 (40%), Gaps = 4/155 (2%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L+L +N IQ + A F L L + RNS R ++ F GL + +++ +N
Sbjct: 76 NTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWL 135
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLAR-NQLRVLPRSVLRGQ 333
+ F L LR L L + I +P + P L L L +L + G
Sbjct: 136 TVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGL 195
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
L L L + ++ P L L LE M GN
Sbjct: 196 FNLKYLNLGMCNIKDM-PNL-TPLVGLEELEMSGN 228
Score = 31.5 bits (68), Expect = 5.4
Identities = 26/114 (22%), Positives = 50/114 (43%), Gaps = 2/114 (1%)
Query: 110 LNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPL 169
++ AF+GL L N G + L L L ++ + F L
Sbjct: 187 ISEGAFEGL--FNLKYLNLGMCNIKDMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSL 244
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
K L + +++++++ +AF GL L +LN+ N ++++ F L + L L+
Sbjct: 245 KKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLH 298
>AF196976-1|AAG28019.2| 653|Homo sapiens brain tumor associated
protein LRRC4 protein.
Length = 653
Score = 70.1 bits (164), Expect = 1e-11
Identities = 57/215 (26%), Positives = 94/215 (43%), Gaps = 24/215 (11%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+YL L + I ++ D F L+ LE L + N I I GAF GL ++ L L N +
Sbjct: 78 RYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTV 137
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPA 288
+P+G F +L L + N + S F + + + + L + E F L
Sbjct: 138 IPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFN 197
Query: 289 LRTLQLDLSSIRELP--------EE---------------FISNSPLRTLSLARNQLRVL 325
L+ L L + +I+++P EE F S L+ L + +Q+ ++
Sbjct: 198 LKYLNLGMCNIKDMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLI 257
Query: 326 PRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL 360
R+ G L L L++N ++ L +LF LR L
Sbjct: 258 ERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYL 292
Score = 66.5 bits (155), Expect = 2e-10
Identities = 51/172 (29%), Positives = 83/172 (48%), Gaps = 12/172 (6%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
LN+ EN I I A FR LH++ VL L +N I+ + G F L L + N +
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP---- 311
S F L ++E+ + NN ++ F+ +P+L ++LDL +++L E+IS
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSL--MRLDLGELKKL--EYISEGAFEGL 195
Query: 312 --LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALE 361
L+ L+L ++ +P L L L +S N E+ P F L +L+
Sbjct: 196 FNLKYLNLGMCNIKDMPN--LTPLVGLEELEMSGNHFPEIRPGSFHGLSSLK 245
Score = 59.3 bits (137), Expect = 2e-08
Identities = 56/236 (23%), Positives = 100/236 (42%), Gaps = 5/236 (2%)
Query: 81 CSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLR 140
C+ LS + Q + + + +N I + AD F+ L ++ + + V
Sbjct: 61 CTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFN 120
Query: 141 SLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
L L L + + F L+ L L + I +P AF + L +L++ E
Sbjct: 121 GLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGE 180
Query: 201 -NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
++ I+ GAF GL N+ L+L I+ +P L L M N F + +F
Sbjct: 181 LKKLEYISEGAFEGLFNLKYLNLGMCNIKDMPN--LTPLVGLEELEMSGNHFPEIRPGSF 238
Query: 260 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
GL ++++ + N+ ++ F L +L L L +++ LP + +PLR L
Sbjct: 239 HGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLF--TPLRYL 292
Score = 49.6 bits (113), Expect = 2e-05
Identities = 43/155 (27%), Positives = 63/155 (40%), Gaps = 4/155 (2%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L+L +N IQ + A F L L + RNS R ++ F GL + +++ +N
Sbjct: 76 NTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWL 135
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLAR-NQLRVLPRSVLRGQ 333
+ F L LR L L + I +P + P L L L +L + G
Sbjct: 136 TVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGL 195
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
L L L + ++ P L L LE M GN
Sbjct: 196 FNLKYLNLGMCNIKDM-PNL-TPLVGLEELEMSGN 228
Score = 48.0 bits (109), Expect = 6e-05
Identities = 54/263 (20%), Positives = 105/263 (39%), Gaps = 12/263 (4%)
Query: 15 CPEQCWCTDGEELNYQCSRPSTNLIVGARPRD--YVNIDCMGGELVCAE-FPEIDTPATT 71
CP C C++ + C+R + + P + Y+N+ +++ A+ F +
Sbjct: 46 CPSVCSCSN-QFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRHLHHLEVL 104
Query: 72 QLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQ 131
QL S+R+ + + L E +F N + + + AF+ L +
Sbjct: 105 QLGRNSIRQIEVGAFNGLASLNTLE-----LFDNWLTVIPSGAFEYLSKLRELWLRNNPI 159
Query: 132 TTVPVDVLRSLPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGL 190
++P +P L L + + + F LKYL L I +P+ L
Sbjct: 160 ESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIKDMPN--LTPL 217
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS 250
LE+L + N I G+F GL ++ L + +++ + F L+ L + N+
Sbjct: 218 VGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNN 277
Query: 251 FRYLDSETFRGLDHIQEIKISNN 273
L + F L ++ E+ + +N
Sbjct: 278 LSSLPHDLFTPLRYLVELHLHHN 300
>BC101073-1|AAI01074.1| 841|Homo sapiens SLIT and NTRK-like family,
member 6 protein.
Length = 841
Score = 69.7 bits (163), Expect = 2e-11
Identities = 41/132 (31%), Positives = 63/132 (47%)
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
QL++ N + + F GL N + L N I + G F L L + NS L
Sbjct: 68 QLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEIL 127
Query: 255 DSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRT 314
+TF GL++++ ++ NN ++ + FS L L+ L L+ ++I LP PL
Sbjct: 128 KEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTH 187
Query: 315 LSLARNQLRVLP 326
L L NQL+ LP
Sbjct: 188 LDLRGNQLQTLP 199
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/130 (32%), Positives = 59/130 (45%), Gaps = 2/130 (1%)
Query: 145 LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIA 204
L L R L F N L+ L L+ +T L FLGL+ LE L + N I
Sbjct: 389 LEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIK 448
Query: 205 NITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD-SETFRGLD 263
I G F + + VL LN N +Q LP +F+ P L + + N F +L S LD
Sbjct: 449 EILPGTFNPMPKLKVLYLNNNLLQVLPPHIFSGVP-LTKVNLKTNQFTHLPVSNILDDLD 507
Query: 264 HIQEIKISNN 273
+ +I + +N
Sbjct: 508 LLTQIDLEDN 517
Score = 52.4 bits (120), Expect = 3e-06
Identities = 36/100 (36%), Positives = 50/100 (50%), Gaps = 3/100 (3%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
LK L ++ + +L +D F GL LE L N I I AF L+ + VL LN N I+
Sbjct: 114 LKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIE 173
Query: 229 ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEI 268
+LP +F P L +L + N + L F L+HI I
Sbjct: 174 SLPPNIFRFVP-LTHLDLRGNQLQTLPYVGF--LEHIGRI 210
Score = 47.2 bits (107), Expect = 1e-04
Identities = 30/111 (27%), Positives = 52/111 (46%), Gaps = 1/111 (0%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
LE L++ N I + G+F L + L LN N + L G+F L L + N+ +
Sbjct: 389 LEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIK 448
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP 303
+ TF + ++ + ++NN+ L +FS +P L + L + LP
Sbjct: 449 EILPGTFNPMPKLKVLYLNNNLLQVLPPHIFSGVP-LTKVNLKTNQFTHLP 498
Score = 41.5 bits (93), Expect = 0.005
Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 1/108 (0%)
Query: 266 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRV 324
+++ ++ N+ +L ++ L L L + I L E F++ + L+ L L N L
Sbjct: 366 RKLILAGNIIHSLMKSDLVEYFTLEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTK 425
Query: 325 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 372
L + + G L L L YNA+ E+ P F + L+ ++ N LQV
Sbjct: 426 LSKGMFLGLHNLEYLYLEYNAIKEILPGTFNPMPKLKVLYLNNNLLQV 473
Score = 32.3 bits (70), Expect = 3.1
Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 2/123 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I + AF GLG+ + N + + D L L + + + + F+
Sbjct: 98 NNIADIEIGAFNGLGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFS 157
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANIT-AGAFRGLHNVTVLSLN 223
LK L L+D I LP + F + L L++ N++ + G + + L L
Sbjct: 158 KLNRLKVLILNDNAIESLPPNIFRFV-PLTHLDLRGNQLQTLPYVGFLEHIGRILDLQLE 216
Query: 224 KNR 226
N+
Sbjct: 217 DNK 219
>BC101072-1|AAI01073.1| 841|Homo sapiens SLIT and NTRK-like family,
member 6 protein.
Length = 841
Score = 69.7 bits (163), Expect = 2e-11
Identities = 41/132 (31%), Positives = 63/132 (47%)
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
QL++ N + + F GL N + L N I + G F L L + NS L
Sbjct: 68 QLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEIL 127
Query: 255 DSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRT 314
+TF GL++++ ++ NN ++ + FS L L+ L L+ ++I LP PL
Sbjct: 128 KEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTH 187
Query: 315 LSLARNQLRVLP 326
L L NQL+ LP
Sbjct: 188 LDLRGNQLQTLP 199
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/130 (32%), Positives = 59/130 (45%), Gaps = 2/130 (1%)
Query: 145 LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIA 204
L L R L F N L+ L L+ +T L FLGL+ LE L + N I
Sbjct: 389 LEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIK 448
Query: 205 NITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD-SETFRGLD 263
I G F + + VL LN N +Q LP +F+ P L + + N F +L S LD
Sbjct: 449 EILPGTFNPMPKLKVLYLNNNLLQVLPPHIFSGVP-LTKVNLKTNQFTHLPVSNILDDLD 507
Query: 264 HIQEIKISNN 273
+ +I + +N
Sbjct: 508 LLTQIDLEDN 517
Score = 52.4 bits (120), Expect = 3e-06
Identities = 36/100 (36%), Positives = 50/100 (50%), Gaps = 3/100 (3%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
LK L ++ + +L +D F GL LE L N I I AF L+ + VL LN N I+
Sbjct: 114 LKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIE 173
Query: 229 ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEI 268
+LP +F P L +L + N + L F L+HI I
Sbjct: 174 SLPPNIFRFVP-LTHLDLRGNQLQTLPYVGF--LEHIGRI 210
Score = 47.2 bits (107), Expect = 1e-04
Identities = 30/111 (27%), Positives = 52/111 (46%), Gaps = 1/111 (0%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
LE L++ N I + G+F L + L LN N + L G+F L L + N+ +
Sbjct: 389 LEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIK 448
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP 303
+ TF + ++ + ++NN+ L +FS +P L + L + LP
Sbjct: 449 EILPGTFNPMPKLKVLYLNNNLLQVLPPHIFSGVP-LTKVNLKTNQFTHLP 498
Score = 41.5 bits (93), Expect = 0.005
Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 1/108 (0%)
Query: 266 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRV 324
+++ ++ N+ +L ++ L L L + I L E F++ + L+ L L N L
Sbjct: 366 RKLILAGNIIHSLMKSDLVEYFTLEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTK 425
Query: 325 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 372
L + + G L L L YNA+ E+ P F + L+ ++ N LQV
Sbjct: 426 LSKGMFLGLHNLEYLYLEYNAIKEILPGTFNPMPKLKVLYLNNNLLQV 473
Score = 32.3 bits (70), Expect = 3.1
Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 2/123 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I + AF GLG+ + N + + D L L + + + + F+
Sbjct: 98 NNIADIEIGAFNGLGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFS 157
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANIT-AGAFRGLHNVTVLSLN 223
LK L L+D I LP + F + L L++ N++ + G + + L L
Sbjct: 158 KLNRLKVLILNDNAIESLPPNIFRFV-PLTHLDLRGNQLQTLPYVGFLEHIGRILDLQLE 216
Query: 224 KNR 226
N+
Sbjct: 217 DNK 219
>BC101071-1|AAI01072.1| 841|Homo sapiens SLIT and NTRK-like family,
member 6 protein.
Length = 841
Score = 69.7 bits (163), Expect = 2e-11
Identities = 41/132 (31%), Positives = 63/132 (47%)
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
QL++ N + + F GL N + L N I + G F L L + NS L
Sbjct: 68 QLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEIL 127
Query: 255 DSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRT 314
+TF GL++++ ++ NN ++ + FS L L+ L L+ ++I LP PL
Sbjct: 128 KEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTH 187
Query: 315 LSLARNQLRVLP 326
L L NQL+ LP
Sbjct: 188 LDLRGNQLQTLP 199
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/130 (32%), Positives = 59/130 (45%), Gaps = 2/130 (1%)
Query: 145 LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIA 204
L L R L F N L+ L L+ +T L FLGL+ LE L + N I
Sbjct: 389 LEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIK 448
Query: 205 NITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD-SETFRGLD 263
I G F + + VL LN N +Q LP +F+ P L + + N F +L S LD
Sbjct: 449 EILPGTFNPMPKLKVLYLNNNLLQVLPPHIFSGVP-LTKVNLKTNQFTHLPVSNILDDLD 507
Query: 264 HIQEIKISNN 273
+ +I + +N
Sbjct: 508 LLTQIDLEDN 517
Score = 52.4 bits (120), Expect = 3e-06
Identities = 36/100 (36%), Positives = 50/100 (50%), Gaps = 3/100 (3%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
LK L ++ + +L +D F GL LE L N I I AF L+ + VL LN N I+
Sbjct: 114 LKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIE 173
Query: 229 ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEI 268
+LP +F P L +L + N + L F L+HI I
Sbjct: 174 SLPPNIFRFVP-LTHLDLRGNQLQTLPYVGF--LEHIGRI 210
Score = 47.2 bits (107), Expect = 1e-04
Identities = 30/111 (27%), Positives = 52/111 (46%), Gaps = 1/111 (0%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
LE L++ N I + G+F L + L LN N + L G+F L L + N+ +
Sbjct: 389 LEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIK 448
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP 303
+ TF + ++ + ++NN+ L +FS +P L + L + LP
Sbjct: 449 EILPGTFNPMPKLKVLYLNNNLLQVLPPHIFSGVP-LTKVNLKTNQFTHLP 498
Score = 41.5 bits (93), Expect = 0.005
Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 1/108 (0%)
Query: 266 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRV 324
+++ ++ N+ +L ++ L L L + I L E F++ + L+ L L N L
Sbjct: 366 RKLILAGNIIHSLMKSDLVEYFTLEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTK 425
Query: 325 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 372
L + + G L L L YNA+ E+ P F + L+ ++ N LQV
Sbjct: 426 LSKGMFLGLHNLEYLYLEYNAIKEILPGTFNPMPKLKVLYLNNNLLQV 473
Score = 32.3 bits (70), Expect = 3.1
Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 2/123 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I + AF GLG+ + N + + D L L + + + + F+
Sbjct: 98 NNIADIEIGAFNGLGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFS 157
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANIT-AGAFRGLHNVTVLSLN 223
LK L L+D I LP + F + L L++ N++ + G + + L L
Sbjct: 158 KLNRLKVLILNDNAIESLPPNIFRFV-PLTHLDLRGNQLQTLPYVGFLEHIGRILDLQLE 216
Query: 224 KNR 226
N+
Sbjct: 217 DNK 219
>BC101070-1|AAI01071.1| 841|Homo sapiens SLIT and NTRK-like family,
member 6 protein.
Length = 841
Score = 69.7 bits (163), Expect = 2e-11
Identities = 41/132 (31%), Positives = 63/132 (47%)
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
QL++ N + + F GL N + L N I + G F L L + NS L
Sbjct: 68 QLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEIL 127
Query: 255 DSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRT 314
+TF GL++++ ++ NN ++ + FS L L+ L L+ ++I LP PL
Sbjct: 128 KEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTH 187
Query: 315 LSLARNQLRVLP 326
L L NQL+ LP
Sbjct: 188 LDLRGNQLQTLP 199
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/130 (32%), Positives = 59/130 (45%), Gaps = 2/130 (1%)
Query: 145 LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIA 204
L L R L F N L+ L L+ +T L FLGL+ LE L + N I
Sbjct: 389 LEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIK 448
Query: 205 NITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD-SETFRGLD 263
I G F + + VL LN N +Q LP +F+ P L + + N F +L S LD
Sbjct: 449 EILPGTFNPMPKLKVLYLNNNLLQVLPPHIFSGVP-LTKVNLKTNQFTHLPVSNILDDLD 507
Query: 264 HIQEIKISNN 273
+ +I + +N
Sbjct: 508 LLTQIDLEDN 517
Score = 52.4 bits (120), Expect = 3e-06
Identities = 36/100 (36%), Positives = 50/100 (50%), Gaps = 3/100 (3%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
LK L ++ + +L +D F GL LE L N I I AF L+ + VL LN N I+
Sbjct: 114 LKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIE 173
Query: 229 ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEI 268
+LP +F P L +L + N + L F L+HI I
Sbjct: 174 SLPPNIFRFVP-LTHLDLRGNQLQTLPYVGF--LEHIGRI 210
Score = 47.2 bits (107), Expect = 1e-04
Identities = 30/111 (27%), Positives = 52/111 (46%), Gaps = 1/111 (0%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
LE L++ N I + G+F L + L LN N + L G+F L L + N+ +
Sbjct: 389 LEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIK 448
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP 303
+ TF + ++ + ++NN+ L +FS +P L + L + LP
Sbjct: 449 EILPGTFNPMPKLKVLYLNNNLLQVLPPHIFSGVP-LTKVNLKTNQFTHLP 498
Score = 41.5 bits (93), Expect = 0.005
Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 1/108 (0%)
Query: 266 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRV 324
+++ ++ N+ +L ++ L L L + I L E F++ + L+ L L N L
Sbjct: 366 RKLILAGNIIHSLMKSDLVEYFTLEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTK 425
Query: 325 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 372
L + + G L L L YNA+ E+ P F + L+ ++ N LQV
Sbjct: 426 LSKGMFLGLHNLEYLYLEYNAIKEILPGTFNPMPKLKVLYLNNNLLQV 473
Score = 32.3 bits (70), Expect = 3.1
Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 2/123 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I + AF GLG+ + N + + D L L + + + + F+
Sbjct: 98 NNIADIEIGAFNGLGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFS 157
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANIT-AGAFRGLHNVTVLSLN 223
LK L L+D I LP + F + L L++ N++ + G + + L L
Sbjct: 158 KLNRLKVLILNDNAIESLPPNIFRFV-PLTHLDLRGNQLQTLPYVGFLEHIGRILDLQLE 216
Query: 224 KNR 226
N+
Sbjct: 217 DNK 219
>AK026427-1|BAB15480.1| 440|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22774 fis, clone KAIA1575. ).
Length = 440
Score = 69.7 bits (163), Expect = 2e-11
Identities = 41/132 (31%), Positives = 63/132 (47%)
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
QL++ N + + F GL N + L N I + G F L L + NS L
Sbjct: 25 QLSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEIL 84
Query: 255 DSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRT 314
+TF GL++++ ++ NN ++ + FS L L+ L L+ ++I LP PL
Sbjct: 85 KEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTH 144
Query: 315 LSLARNQLRVLP 326
L L NQL+ LP
Sbjct: 145 LDLRGNQLQTLP 156
Score = 52.4 bits (120), Expect = 3e-06
Identities = 36/100 (36%), Positives = 50/100 (50%), Gaps = 3/100 (3%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
LK L ++ + +L +D F GL LE L N I I AF L+ + VL LN N I+
Sbjct: 71 LKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIE 130
Query: 229 ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEI 268
+LP +F P L +L + N + L F L+HI I
Sbjct: 131 SLPPNIFRFVP-LTHLDLRGNQLQTLPYVGF--LEHIGRI 167
Score = 52.4 bits (120), Expect = 3e-06
Identities = 29/93 (31%), Positives = 49/93 (52%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
L+ L L + +I VL + +F+ L L++L + N + ++ G F GLHN+ L L N I+
Sbjct: 346 LEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIK 405
Query: 229 ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG 261
+ G F P+L L + S ++ F+G
Sbjct: 406 EILPGTFNPMPKLKVLYLNNTSSKFYHHIFFQG 438
Score = 37.1 bits (82), Expect = 0.11
Identities = 27/79 (34%), Positives = 34/79 (43%)
Query: 145 LTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIA 204
L L R L F N L+ L L+ +T L FLGL+ LE L + N I
Sbjct: 346 LEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIK 405
Query: 205 NITAGAFRGLHNVTVLSLN 223
I G F + + VL LN
Sbjct: 406 EILPGTFNPMPKLKVLYLN 424
Score = 35.9 bits (79), Expect = 0.25
Identities = 21/80 (26%), Positives = 38/80 (47%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
LE L++ N I + G+F L + L LN N + L G+F L L + N+ +
Sbjct: 346 LEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAIK 405
Query: 253 YLDSETFRGLDHIQEIKISN 272
+ TF + ++ + ++N
Sbjct: 406 EILPGTFNPMPKLKVLYLNN 425
Score = 35.1 bits (77), Expect = 0.44
Identities = 26/102 (25%), Positives = 48/102 (47%), Gaps = 1/102 (0%)
Query: 266 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRV 324
+++ ++ N+ +L ++ L L L + I L E F++ + L+ L L N L
Sbjct: 323 RKLILAGNIIHSLMKSDLVEYFTLEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTK 382
Query: 325 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMD 366
L + + G L L L YNA+ E+ P F + L+ ++
Sbjct: 383 LSKGMFLGLHNLEYLYLEYNAIKEILPGTFNPMPKLKVLYLN 424
Score = 32.3 bits (70), Expect = 3.1
Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 2/123 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I + AF GLG+ + N + + D L L + + + + F+
Sbjct: 55 NNIADIEIGAFNGLGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFS 114
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANIT-AGAFRGLHNVTVLSLN 223
LK L L+D I LP + F + L L++ N++ + G + + L L
Sbjct: 115 KLNRLKVLILNDNAIESLPPNIFRFV-PLTHLDLRGNQLQTLPYVGFLEHIGRILDLQLE 173
Query: 224 KNR 226
N+
Sbjct: 174 DNK 176
>AY358115-1|AAQ88482.1| 593|Homo sapiens DAAT9248 protein.
Length = 593
Score = 68.5 bits (160), Expect = 4e-11
Identities = 45/171 (26%), Positives = 83/171 (48%), Gaps = 1/171 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L+LS ++ L L++L++L++ N+++ + GAF GL ++ L L NR++ +
Sbjct: 65 LDLSGNRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIMG 124
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
G+F+ L L + N F L +Q++++ +N + + F+ L L T
Sbjct: 125 PGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLST 184
Query: 292 LQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTL 341
L L+ ++ +P ++ P L L L + LP LRG QL L +
Sbjct: 185 LTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRGLGQLKELEI 235
Score = 54.8 bits (126), Expect = 5e-07
Identities = 50/182 (27%), Positives = 77/182 (42%), Gaps = 2/182 (1%)
Query: 114 AFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLE 173
AF GL + + +TVP L LP L RL L A LK LE
Sbjct: 175 AFAGLAKLSTLTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRGLGQLKELE 234
Query: 174 LSD-AKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
+ + L + +GLN L L + ++++ A L + VL L++N I A+PA
Sbjct: 235 IHLWPSLEALDPGSLVGLN-LSSLAITRCNLSSVPFQALYHLSFLRVLDLSQNPISAIPA 293
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTL 292
+ RL L + + + F GL + +++N TL+E F + L TL
Sbjct: 294 RRLSPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTL 353
Query: 293 QL 294
+L
Sbjct: 354 RL 355
Score = 53.6 bits (123), Expect = 1e-06
Identities = 43/154 (27%), Positives = 65/154 (42%)
Query: 150 LNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAG 209
L+ R L M + L+ L+LS +++ L AF GL L L + N + + G
Sbjct: 67 LSGNRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIMGPG 126
Query: 210 AFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIK 269
F GL +T+L L N+I G F L L + N ++ F GL + +
Sbjct: 127 VFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLSTLT 186
Query: 270 ISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP 303
+ T+ + LPAL L+L I LP
Sbjct: 187 LERCNLSTVPGLALARLPALVALRLRELDIGRLP 220
Score = 52.8 bits (121), Expect = 2e-06
Identities = 52/231 (22%), Positives = 92/231 (39%), Gaps = 1/231 (0%)
Query: 138 VLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
+L L L L+ + TL F L L L ++ ++ F GL+ L L+
Sbjct: 79 MLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIMGPGVFSGLSALTLLD 138
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSE 257
+ N+I GAF L ++ L + N + + G FA +L LT+ R + +
Sbjct: 139 LRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLSTLTLERCNLSTVPGL 198
Query: 258 TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDL-SSIRELPEEFISNSPLRTLS 316
L + +++ L L L+ L++ L S+ L + L +L+
Sbjct: 199 ALARLPALVALRLRELDIGRLPAGALRGLGQLKELEIHLWPSLEALDPGSLVGLNLSSLA 258
Query: 317 LARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 367
+ R L +P L + L L LS N ++ + + L L+ + G
Sbjct: 259 ITRCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRLSPLVRLQELRLSG 309
Score = 47.6 bits (108), Expect = 8e-05
Identities = 38/149 (25%), Positives = 62/149 (41%), Gaps = 1/149 (0%)
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
E L++ N + + G L + L L+ N++ L G F LL L + N R
Sbjct: 63 ELLDLSGNRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRI 122
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL-DLSSIRELPEEFISNSPL 312
+ F GL + + + N + + F L +L+ L++ D + P F + L
Sbjct: 123 MGPGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKL 182
Query: 313 RTLSLARNQLRVLPRSVLRGQTQLTSLTL 341
TL+L R L +P L L +L L
Sbjct: 183 STLTLERCNLSTVPGLALARLPALVALRL 211
Score = 47.2 bits (107), Expect = 1e-04
Identities = 42/156 (26%), Positives = 66/156 (42%), Gaps = 3/156 (1%)
Query: 219 VLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTL 278
+L L+ NR+ L G+ + L L + N L+ F GL + +++ N +
Sbjct: 64 LLDLSGNRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIM 123
Query: 279 KEAVFSNLPALRTLQLDLSSI-RELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLT 337
VFS L AL L L L+ I L F L+ L + N L + G +L+
Sbjct: 124 GPGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLS 183
Query: 338 SLTLSYNAVAELAPELFADLRALETFVMDGNELQVG 373
+LTL ++ + A L AL + EL +G
Sbjct: 184 TLTLERCNLSTVPGLALARLPALVALRL--RELDIG 217
>AL589765-16|CAI17178.1| 593|Homo sapiens leucine rich repeat
neuronal 6D protein.
Length = 593
Score = 68.5 bits (160), Expect = 4e-11
Identities = 45/171 (26%), Positives = 83/171 (48%), Gaps = 1/171 (0%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L+LS ++ L L++L++L++ N+++ + GAF GL ++ L L NR++ +
Sbjct: 65 LDLSGNRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIMG 124
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
G+F+ L L + N F L +Q++++ +N + + F+ L L T
Sbjct: 125 PGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLST 184
Query: 292 LQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTL 341
L L+ ++ +P ++ P L L L + LP LRG QL L +
Sbjct: 185 LTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRGLGQLKELEI 235
Score = 54.8 bits (126), Expect = 5e-07
Identities = 50/182 (27%), Positives = 77/182 (42%), Gaps = 2/182 (1%)
Query: 114 AFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLE 173
AF GL + + +TVP L LP L RL L A LK LE
Sbjct: 175 AFAGLAKLSTLTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRGLGQLKELE 234
Query: 174 LSD-AKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
+ + L + +GLN L L + ++++ A L + VL L++N I A+PA
Sbjct: 235 IHLWPSLEALDPGSLVGLN-LSSLAITRCNLSSVPFQALYHLSFLRVLDLSQNPISAIPA 293
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTL 292
+ RL L + + + F GL + +++N TL+E F + L TL
Sbjct: 294 RRLSPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTL 353
Query: 293 QL 294
+L
Sbjct: 354 RL 355
Score = 53.6 bits (123), Expect = 1e-06
Identities = 43/154 (27%), Positives = 65/154 (42%)
Query: 150 LNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAG 209
L+ R L M + L+ L+LS +++ L AF GL L L + N + + G
Sbjct: 67 LSGNRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIMGPG 126
Query: 210 AFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIK 269
F GL +T+L L N+I G F L L + N ++ F GL + +
Sbjct: 127 VFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLSTLT 186
Query: 270 ISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP 303
+ T+ + LPAL L+L I LP
Sbjct: 187 LERCNLSTVPGLALARLPALVALRLRELDIGRLP 220
Score = 52.8 bits (121), Expect = 2e-06
Identities = 52/231 (22%), Positives = 92/231 (39%), Gaps = 1/231 (0%)
Query: 138 VLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLN 197
+L L L L+ + TL F L L L ++ ++ F GL+ L L+
Sbjct: 79 MLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIMGPGVFSGLSALTLLD 138
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSE 257
+ N+I GAF L ++ L + N + + G FA +L LT+ R + +
Sbjct: 139 LRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLSTLTLERCNLSTVPGL 198
Query: 258 TFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDL-SSIRELPEEFISNSPLRTLS 316
L + +++ L L L+ L++ L S+ L + L +L+
Sbjct: 199 ALARLPALVALRLRELDIGRLPAGALRGLGQLKELEIHLWPSLEALDPGSLVGLNLSSLA 258
Query: 317 LARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDG 367
+ R L +P L + L L LS N ++ + + L L+ + G
Sbjct: 259 ITRCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRLSPLVRLQELRLSG 309
Score = 47.6 bits (108), Expect = 8e-05
Identities = 38/149 (25%), Positives = 62/149 (41%), Gaps = 1/149 (0%)
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
E L++ N + + G L + L L+ N++ L G F LL L + N R
Sbjct: 63 ELLDLSGNRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRI 122
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL-DLSSIRELPEEFISNSPL 312
+ F GL + + + N + + F L +L+ L++ D + P F + L
Sbjct: 123 MGPGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKL 182
Query: 313 RTLSLARNQLRVLPRSVLRGQTQLTSLTL 341
TL+L R L +P L L +L L
Sbjct: 183 STLTLERCNLSTVPGLALARLPALVALRL 211
Score = 47.2 bits (107), Expect = 1e-04
Identities = 42/156 (26%), Positives = 66/156 (42%), Gaps = 3/156 (1%)
Query: 219 VLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTL 278
+L L+ NR+ L G+ + L L + N L+ F GL + +++ N +
Sbjct: 64 LLDLSGNRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIM 123
Query: 279 KEAVFSNLPALRTLQLDLSSI-RELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLT 337
VFS L AL L L L+ I L F L+ L + N L + G +L+
Sbjct: 124 GPGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLS 183
Query: 338 SLTLSYNAVAELAPELFADLRALETFVMDGNELQVG 373
+LTL ++ + A L AL + EL +G
Sbjct: 184 TLTLERCNLSTVPGLALARLPALVALRL--RELDIG 217
>AJ297858-1|CAC82651.1| 649|Homo sapiens hypothetical protein
protein.
Length = 649
Score = 68.5 bits (160), Expect = 4e-11
Identities = 54/181 (29%), Positives = 89/181 (49%), Gaps = 13/181 (7%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
LN+ EN I I A FR LH++ VL L +N I+ + G F L L + N +
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP---- 311
S F L ++E+ + NN ++ F+ +P+L ++LDL +++L E+IS
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSL--MRLDLGELKKL--EYISEGAFEGL 195
Query: 312 --LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRAL-ETFVMDGN 368
L+ L+L ++ +P L L L +S N E+ P F L +L + +VM+ +
Sbjct: 196 FNLKYLNLGMCNIKDMPN--LTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSH 253
Query: 369 E 369
E
Sbjct: 254 E 254
Score = 64.1 bits (149), Expect = 8e-10
Identities = 38/135 (28%), Positives = 63/135 (46%), Gaps = 1/135 (0%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
+YL L + I ++ D F L+ LE L + N I I GAF GL ++ L L N +
Sbjct: 78 RYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTV 137
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT-LKEAVFSNLPA 288
+P+G F +L L + N + S F + + + + L + E F L
Sbjct: 138 IPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFN 197
Query: 289 LRTLQLDLSSIRELP 303
L+ L L + +I+++P
Sbjct: 198 LKYLNLGMCNIKDMP 212
Score = 52.8 bits (121), Expect = 2e-06
Identities = 54/212 (25%), Positives = 89/212 (41%), Gaps = 6/212 (2%)
Query: 134 VPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL 193
+ D R L L +L + F L LEL D +TV+P AF L+ L
Sbjct: 90 IQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKL 149
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNK-NRIQALPAGLFASTPRLLNLTMMRNSFR 252
+L + N I +I + AF + ++ L L + +++ + G F L L + + +
Sbjct: 150 RELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIK 209
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPL 312
D L ++E+++S N ++ F L +L+ L + S R F + L
Sbjct: 210 --DMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSHER---NAFDGLASL 264
Query: 313 RTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
L+LA N L LP + L L L +N
Sbjct: 265 VELNLAHNNLSSLPHDLFTPLRYLVELHLHHN 296
Score = 49.6 bits (113), Expect = 2e-05
Identities = 43/155 (27%), Positives = 63/155 (40%), Gaps = 4/155 (2%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L+L +N IQ + A F L L + RNS R ++ F GL + +++ +N
Sbjct: 76 NTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWL 135
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLAR-NQLRVLPRSVLRGQ 333
+ F L LR L L + I +P + P L L L +L + G
Sbjct: 136 TVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGL 195
Query: 334 TQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
L L L + ++ P L L LE M GN
Sbjct: 196 FNLKYLNLGMCNIKDM-PNL-TPLVGLEELEMSGN 228
>BC101077-1|AAI01078.1| 1041|Homo sapiens toll-like receptor 8
protein.
Length = 1041
Score = 68.1 bits (159), Expect = 5e-11
Identities = 73/274 (26%), Positives = 120/274 (43%), Gaps = 15/274 (5%)
Query: 82 SLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRS 141
+LP ++CL + A V+ + + + L L NA A T + +
Sbjct: 503 NLPDIACL--NLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLD 560
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL-------E 194
L +H+ AG +T H N LK L LS I L D L L
Sbjct: 561 LSYNSHYFRIAG--VTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGN 618
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTP-RLLNLTMMRNSFRY 253
+L++ N+ N F+GL N+T L L+ NR++ +P F + P L L + N ++
Sbjct: 619 RLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKF 678
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPL 312
+ + ++ + + N L L +++ +LRTL L + I LP F+S S L
Sbjct: 679 FNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSL 738
Query: 313 RTLSLARNQLRVLPRSVL--RGQTQLTSLTLSYN 344
+ L L+ N L+ + +S L + T+L+ L L N
Sbjct: 739 KHLDLSSNLLKTINKSALETKTTTKLSMLELHGN 772
Score = 59.7 bits (138), Expect = 2e-08
Identities = 54/194 (27%), Positives = 92/194 (47%), Gaps = 26/194 (13%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIA--------------NITAGAFRGLHNV 217
L+LSD IT + +++F GL L ++N+ N NIT GAF L N+
Sbjct: 68 LDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFLNLKNL 127
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV--- 274
L L N++ +P+GL S L L++++N+ + E L +++ + ++ N
Sbjct: 128 RELLLEDNQLPQIPSGLPES---LTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFN 184
Query: 275 ----PLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVL 330
+++ VF L L L L +S+ +P + S+ LR L L+ Q++ +
Sbjct: 185 KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSS--LRKLFLSNTQIKYISEEDF 242
Query: 331 RGQTQLTSLTLSYN 344
+G LT L LS N
Sbjct: 243 KGLINLTLLDLSGN 256
Score = 56.0 bits (129), Expect = 2e-07
Identities = 62/247 (25%), Positives = 109/247 (44%), Gaps = 16/247 (6%)
Query: 141 SLPKLTHFRLNAGRNI-TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
+LP + L+A N L F+ P +KYL+L++ ++ A L+ LE L++
Sbjct: 503 NLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLS 562
Query: 200 ENE----IANITAGA--FRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
N IA +T + N+ VL+L+ N I L + L+ L N
Sbjct: 563 YNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDI 622
Query: 254 L--DSET-----FRGLDHIQEIKISNNVPLTLKEAVFSNLPA-LRTLQLDLSSIRELPEE 305
L D + F+GL ++ + +S N + F NLPA L L ++ + ++
Sbjct: 623 LWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWT 682
Query: 306 FISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 364
+ P L L L N+L L S+ + L +L LS+N ++ L +++ +L+
Sbjct: 683 LLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLD 742
Query: 365 MDGNELQ 371
+ N L+
Sbjct: 743 LSSNLLK 749
Score = 50.8 bits (116), Expect = 8e-06
Identities = 47/171 (27%), Positives = 75/171 (43%), Gaps = 23/171 (13%)
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG 261
E NI G F L N+ +LSL+ N + +P L +S L L + +Y+ E F+G
Sbjct: 188 EKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSS---LRKLFLSNTQIKYISEEDFKG 244
Query: 262 LDHIQEIKISNNVP-----------------LTLKEAVFSNLPALRTLQLDLSSIRELPE 304
L ++ + +S N P + + F NL LR L L +S+R++
Sbjct: 245 LINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINA 304
Query: 305 EFISNSP-LRTLSLARNQL--RVLPRSVLRGQTQLTSLTLSYNAVAELAPE 352
+ N P L+ L L N L + + L +L L LS+N + P+
Sbjct: 305 AWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQ 355
Score = 39.5 bits (88), Expect = 0.020
Identities = 55/197 (27%), Positives = 94/197 (47%), Gaps = 26/197 (13%)
Query: 173 ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
E S+ ++ +P +G V E L++ +N I +IT +F+GL N+T ++LN N
Sbjct: 48 ECSNRRLQEVPQT--VGKYVTE-LDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQN 104
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLP-ALRT 291
G N + N D F L +++E+ + +N L + + S LP +L
Sbjct: 105 G---------NPGIQSNGLNITDG-AFLNLKNLRELLLEDN---QLPQ-IPSGLPESLTE 150
Query: 292 LQLDLSSIRELPEEFISN-SPLRTLSLARN-------QLRVLPRSVLRGQTQLTSLTLSY 343
L L ++I + +E IS L+ L LA N + + V T L L+LS+
Sbjct: 151 LSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSF 210
Query: 344 NAVAELAPELFADLRAL 360
N+++ + P+L + LR L
Sbjct: 211 NSLSHVPPKLPSSLRKL 227
Score = 35.5 bits (78), Expect = 0.33
Identities = 45/191 (23%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Query: 151 NAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENE-IANITAG 209
+ G +I + F N L+YL LS + + F + L+ L++ N + I +G
Sbjct: 271 DGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASG 330
Query: 210 AF-RGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEI 268
AF L + +L L+ N I+ S P+ +N++ + L + RG QE+
Sbjct: 331 AFLTMLPRLEILDLSFNYIK-------GSYPQHINISRNFSKLLSLRALHLRGY-VFQEL 382
Query: 269 KISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPR 327
+ + PL LP L T+ L ++ I+++ + N S L + L+ N++ L +
Sbjct: 383 REDDFQPL-------MQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVK 435
Query: 328 SVLRGQTQLTS 338
+ +S
Sbjct: 436 DTRQSYANSSS 446
>BC101076-1|AAI01077.1| 1041|Homo sapiens toll-like receptor 8
protein.
Length = 1041
Score = 68.1 bits (159), Expect = 5e-11
Identities = 73/274 (26%), Positives = 120/274 (43%), Gaps = 15/274 (5%)
Query: 82 SLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRS 141
+LP ++CL + A V+ + + + L L NA A T + +
Sbjct: 503 NLPDIACL--NLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLD 560
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL-------E 194
L +H+ AG +T H N LK L LS I L D L L
Sbjct: 561 LSYNSHYFRIAG--VTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGN 618
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTP-RLLNLTMMRNSFRY 253
+L++ N+ N F+GL N+T L L+ NR++ +P F + P L L + N ++
Sbjct: 619 RLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKF 678
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPL 312
+ + ++ + + N L L +++ +LRTL L + I LP F+S S L
Sbjct: 679 FNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSL 738
Query: 313 RTLSLARNQLRVLPRSVL--RGQTQLTSLTLSYN 344
+ L L+ N L+ + +S L + T+L+ L L N
Sbjct: 739 KHLDLSSNLLKTINKSALETKTTTKLSMLELHGN 772
Score = 59.7 bits (138), Expect = 2e-08
Identities = 54/194 (27%), Positives = 92/194 (47%), Gaps = 26/194 (13%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIA--------------NITAGAFRGLHNV 217
L+LSD IT + +++F GL L ++N+ N NIT GAF L N+
Sbjct: 68 LDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFLNLKNL 127
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV--- 274
L L N++ +P+GL S L L++++N+ + E L +++ + ++ N
Sbjct: 128 RELLLEDNQLPQIPSGLPES---LTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFN 184
Query: 275 ----PLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVL 330
+++ VF L L L L +S+ +P + S+ LR L L+ Q++ +
Sbjct: 185 KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSS--LRKLFLSNTQIKYISEEDF 242
Query: 331 RGQTQLTSLTLSYN 344
+G LT L LS N
Sbjct: 243 KGLINLTLLDLSGN 256
Score = 56.0 bits (129), Expect = 2e-07
Identities = 62/247 (25%), Positives = 109/247 (44%), Gaps = 16/247 (6%)
Query: 141 SLPKLTHFRLNAGRNI-TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
+LP + L+A N L F+ P +KYL+L++ ++ A L+ LE L++
Sbjct: 503 NLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLS 562
Query: 200 ENE----IANITAGA--FRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
N IA +T + N+ VL+L+ N I L + L+ L N
Sbjct: 563 YNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDI 622
Query: 254 L--DSET-----FRGLDHIQEIKISNNVPLTLKEAVFSNLPA-LRTLQLDLSSIRELPEE 305
L D + F+GL ++ + +S N + F NLPA L L ++ + ++
Sbjct: 623 LWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWT 682
Query: 306 FISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 364
+ P L L L N+L L S+ + L +L LS+N ++ L +++ +L+
Sbjct: 683 LLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLD 742
Query: 365 MDGNELQ 371
+ N L+
Sbjct: 743 LSSNLLK 749
Score = 50.8 bits (116), Expect = 8e-06
Identities = 47/171 (27%), Positives = 75/171 (43%), Gaps = 23/171 (13%)
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG 261
E NI G F L N+ +LSL+ N + +P L +S L L + +Y+ E F+G
Sbjct: 188 EKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSS---LRKLFLSNTQIKYISEEDFKG 244
Query: 262 LDHIQEIKISNNVP-----------------LTLKEAVFSNLPALRTLQLDLSSIRELPE 304
L ++ + +S N P + + F NL LR L L +S+R++
Sbjct: 245 LINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINA 304
Query: 305 EFISNSP-LRTLSLARNQL--RVLPRSVLRGQTQLTSLTLSYNAVAELAPE 352
+ N P L+ L L N L + + L +L L LS+N + P+
Sbjct: 305 AWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQ 355
Score = 39.5 bits (88), Expect = 0.020
Identities = 55/197 (27%), Positives = 94/197 (47%), Gaps = 26/197 (13%)
Query: 173 ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
E S+ ++ +P +G V E L++ +N I +IT +F+GL N+T ++LN N
Sbjct: 48 ECSNRRLQEVPQT--VGKYVTE-LDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQN 104
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLP-ALRT 291
G N + N D F L +++E+ + +N L + + S LP +L
Sbjct: 105 G---------NPGIQSNGLNITDG-AFLNLKNLRELLLEDN---QLPQ-IPSGLPESLTE 150
Query: 292 LQLDLSSIRELPEEFISN-SPLRTLSLARN-------QLRVLPRSVLRGQTQLTSLTLSY 343
L L ++I + +E IS L+ L LA N + + V T L L+LS+
Sbjct: 151 LSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSF 210
Query: 344 NAVAELAPELFADLRAL 360
N+++ + P+L + LR L
Sbjct: 211 NSLSHVPPKLPSSLRKL 227
Score = 35.5 bits (78), Expect = 0.33
Identities = 45/191 (23%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Query: 151 NAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENE-IANITAG 209
+ G +I + F N L+YL LS + + F + L+ L++ N + I +G
Sbjct: 271 DGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASG 330
Query: 210 AF-RGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEI 268
AF L + +L L+ N I+ S P+ +N++ + L + RG QE+
Sbjct: 331 AFLTMLPRLEILDLSFNYIK-------GSYPQHINISRNFSKLLSLRALHLRGY-VFQEL 382
Query: 269 KISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPR 327
+ + PL LP L T+ L ++ I+++ + N S L + L+ N++ L +
Sbjct: 383 REDDFQPL-------MQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVK 435
Query: 328 SVLRGQTQLTS 338
+ +S
Sbjct: 436 DTRQSYANSSS 446
>BC101075-1|AAI01076.1| 1041|Homo sapiens toll-like receptor 8
protein.
Length = 1041
Score = 68.1 bits (159), Expect = 5e-11
Identities = 73/274 (26%), Positives = 120/274 (43%), Gaps = 15/274 (5%)
Query: 82 SLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRS 141
+LP ++CL + A V+ + + + L L NA A T + +
Sbjct: 503 NLPDIACL--NLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLD 560
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL-------E 194
L +H+ AG +T H N LK L LS I L D L L
Sbjct: 561 LSYNSHYFRIAG--VTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGN 618
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTP-RLLNLTMMRNSFRY 253
+L++ N+ N F+GL N+T L L+ NR++ +P F + P L L + N ++
Sbjct: 619 RLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKF 678
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPL 312
+ + ++ + + N L L +++ +LRTL L + I LP F+S S L
Sbjct: 679 FNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSL 738
Query: 313 RTLSLARNQLRVLPRSVL--RGQTQLTSLTLSYN 344
+ L L+ N L+ + +S L + T+L+ L L N
Sbjct: 739 KHLDLSSNLLKTINKSALETKTTTKLSMLELHGN 772
Score = 59.7 bits (138), Expect = 2e-08
Identities = 54/194 (27%), Positives = 92/194 (47%), Gaps = 26/194 (13%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIA--------------NITAGAFRGLHNV 217
L+LSD IT + +++F GL L ++N+ N NIT GAF L N+
Sbjct: 68 LDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFLNLKNL 127
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV--- 274
L L N++ +P+GL S L L++++N+ + E L +++ + ++ N
Sbjct: 128 RELLLEDNQLPQIPSGLPES---LTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFN 184
Query: 275 ----PLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVL 330
+++ VF L L L L +S+ +P + S+ LR L L+ Q++ +
Sbjct: 185 KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSS--LRKLFLSNTQIKYISEEDF 242
Query: 331 RGQTQLTSLTLSYN 344
+G LT L LS N
Sbjct: 243 KGLINLTLLDLSGN 256
Score = 56.0 bits (129), Expect = 2e-07
Identities = 62/247 (25%), Positives = 109/247 (44%), Gaps = 16/247 (6%)
Query: 141 SLPKLTHFRLNAGRNI-TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
+LP + L+A N L F+ P +KYL+L++ ++ A L+ LE L++
Sbjct: 503 NLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLS 562
Query: 200 ENE----IANITAGA--FRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
N IA +T + N+ VL+L+ N I L + L+ L N
Sbjct: 563 YNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDI 622
Query: 254 L--DSET-----FRGLDHIQEIKISNNVPLTLKEAVFSNLPA-LRTLQLDLSSIRELPEE 305
L D + F+GL ++ + +S N + F NLPA L L ++ + ++
Sbjct: 623 LWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWT 682
Query: 306 FISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 364
+ P L L L N+L L S+ + L +L LS+N ++ L +++ +L+
Sbjct: 683 LLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLD 742
Query: 365 MDGNELQ 371
+ N L+
Sbjct: 743 LSSNLLK 749
Score = 50.8 bits (116), Expect = 8e-06
Identities = 47/171 (27%), Positives = 75/171 (43%), Gaps = 23/171 (13%)
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG 261
E NI G F L N+ +LSL+ N + +P L +S L L + +Y+ E F+G
Sbjct: 188 EKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSS---LRKLFLSNTQIKYISEEDFKG 244
Query: 262 LDHIQEIKISNNVP-----------------LTLKEAVFSNLPALRTLQLDLSSIRELPE 304
L ++ + +S N P + + F NL LR L L +S+R++
Sbjct: 245 LINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINA 304
Query: 305 EFISNSP-LRTLSLARNQL--RVLPRSVLRGQTQLTSLTLSYNAVAELAPE 352
+ N P L+ L L N L + + L +L L LS+N + P+
Sbjct: 305 AWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQ 355
Score = 39.5 bits (88), Expect = 0.020
Identities = 55/197 (27%), Positives = 94/197 (47%), Gaps = 26/197 (13%)
Query: 173 ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
E S+ ++ +P +G V E L++ +N I +IT +F+GL N+T ++LN N
Sbjct: 48 ECSNRRLQEVPQT--VGKYVTE-LDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQN 104
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLP-ALRT 291
G N + N D F L +++E+ + +N L + + S LP +L
Sbjct: 105 G---------NPGIQSNGLNITDG-AFLNLKNLRELLLEDN---QLPQ-IPSGLPESLTE 150
Query: 292 LQLDLSSIRELPEEFISN-SPLRTLSLARN-------QLRVLPRSVLRGQTQLTSLTLSY 343
L L ++I + +E IS L+ L LA N + + V T L L+LS+
Sbjct: 151 LSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSF 210
Query: 344 NAVAELAPELFADLRAL 360
N+++ + P+L + LR L
Sbjct: 211 NSLSHVPPKLPSSLRKL 227
Score = 35.5 bits (78), Expect = 0.33
Identities = 45/191 (23%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Query: 151 NAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENE-IANITAG 209
+ G +I + F N L+YL LS + + F + L+ L++ N + I +G
Sbjct: 271 DGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASG 330
Query: 210 AF-RGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEI 268
AF L + +L L+ N I+ S P+ +N++ + L + RG QE+
Sbjct: 331 AFLTMLPRLEILDLSFNYIK-------GSYPQHINISRNFSKLLSLRALHLRGY-VFQEL 382
Query: 269 KISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPR 327
+ + PL LP L T+ L ++ I+++ + N S L + L+ N++ L +
Sbjct: 383 REDDFQPL-------MQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVK 435
Query: 328 SVLRGQTQLTS 338
+ +S
Sbjct: 436 DTRQSYANSSS 446
>BC101074-1|AAI01075.1| 1041|Homo sapiens toll-like receptor 8
protein.
Length = 1041
Score = 68.1 bits (159), Expect = 5e-11
Identities = 73/274 (26%), Positives = 120/274 (43%), Gaps = 15/274 (5%)
Query: 82 SLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRS 141
+LP ++CL + A V+ + + + L L NA A T + +
Sbjct: 503 NLPDIACL--NLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLD 560
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL-------E 194
L +H+ AG +T H N LK L LS I L D L L
Sbjct: 561 LSYNSHYFRIAG--VTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGN 618
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTP-RLLNLTMMRNSFRY 253
+L++ N+ N F+GL N+T L L+ NR++ +P F + P L L + N ++
Sbjct: 619 RLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKF 678
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPL 312
+ + ++ + + N L L +++ +LRTL L + I LP F+S S L
Sbjct: 679 FNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSL 738
Query: 313 RTLSLARNQLRVLPRSVL--RGQTQLTSLTLSYN 344
+ L L+ N L+ + +S L + T+L+ L L N
Sbjct: 739 KHLDLSSNLLKTINKSALETKTTTKLSMLELHGN 772
Score = 59.7 bits (138), Expect = 2e-08
Identities = 54/194 (27%), Positives = 92/194 (47%), Gaps = 26/194 (13%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIA--------------NITAGAFRGLHNV 217
L+LSD IT + +++F GL L ++N+ N NIT GAF L N+
Sbjct: 68 LDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFLNLKNL 127
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV--- 274
L L N++ +P+GL S L L++++N+ + E L +++ + ++ N
Sbjct: 128 RELLLEDNQLPQIPSGLPES---LTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFN 184
Query: 275 ----PLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVL 330
+++ VF L L L L +S+ +P + S+ LR L L+ Q++ +
Sbjct: 185 KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSS--LRKLFLSNTQIKYISEEDF 242
Query: 331 RGQTQLTSLTLSYN 344
+G LT L LS N
Sbjct: 243 KGLINLTLLDLSGN 256
Score = 56.0 bits (129), Expect = 2e-07
Identities = 62/247 (25%), Positives = 109/247 (44%), Gaps = 16/247 (6%)
Query: 141 SLPKLTHFRLNAGRNI-TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
+LP + L+A N L F+ P +KYL+L++ ++ A L+ LE L++
Sbjct: 503 NLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLS 562
Query: 200 ENE----IANITAGA--FRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
N IA +T + N+ VL+L+ N I L + L+ L N
Sbjct: 563 YNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDI 622
Query: 254 L--DSET-----FRGLDHIQEIKISNNVPLTLKEAVFSNLPA-LRTLQLDLSSIRELPEE 305
L D + F+GL ++ + +S N + F NLPA L L ++ + ++
Sbjct: 623 LWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWT 682
Query: 306 FISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 364
+ P L L L N+L L S+ + L +L LS+N ++ L +++ +L+
Sbjct: 683 LLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLD 742
Query: 365 MDGNELQ 371
+ N L+
Sbjct: 743 LSSNLLK 749
Score = 50.8 bits (116), Expect = 8e-06
Identities = 47/171 (27%), Positives = 75/171 (43%), Gaps = 23/171 (13%)
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG 261
E NI G F L N+ +LSL+ N + +P L +S L L + +Y+ E F+G
Sbjct: 188 EKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSS---LRKLFLSNTQIKYISEEDFKG 244
Query: 262 LDHIQEIKISNNVP-----------------LTLKEAVFSNLPALRTLQLDLSSIRELPE 304
L ++ + +S N P + + F NL LR L L +S+R++
Sbjct: 245 LINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINA 304
Query: 305 EFISNSP-LRTLSLARNQL--RVLPRSVLRGQTQLTSLTLSYNAVAELAPE 352
+ N P L+ L L N L + + L +L L LS+N + P+
Sbjct: 305 AWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQ 355
Score = 39.5 bits (88), Expect = 0.020
Identities = 55/197 (27%), Positives = 94/197 (47%), Gaps = 26/197 (13%)
Query: 173 ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
E S+ ++ +P +G V E L++ +N I +IT +F+GL N+T ++LN N
Sbjct: 48 ECSNRRLQEVPQT--VGKYVTE-LDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQN 104
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLP-ALRT 291
G N + N D F L +++E+ + +N L + + S LP +L
Sbjct: 105 G---------NPGIQSNGLNITDG-AFLNLKNLRELLLEDN---QLPQ-IPSGLPESLTE 150
Query: 292 LQLDLSSIRELPEEFISN-SPLRTLSLARN-------QLRVLPRSVLRGQTQLTSLTLSY 343
L L ++I + +E IS L+ L LA N + + V T L L+LS+
Sbjct: 151 LSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSF 210
Query: 344 NAVAELAPELFADLRAL 360
N+++ + P+L + LR L
Sbjct: 211 NSLSHVPPKLPSSLRKL 227
Score = 35.5 bits (78), Expect = 0.33
Identities = 45/191 (23%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Query: 151 NAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENE-IANITAG 209
+ G +I + F N L+YL LS + + F + L+ L++ N + I +G
Sbjct: 271 DGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASG 330
Query: 210 AF-RGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEI 268
AF L + +L L+ N I+ S P+ +N++ + L + RG QE+
Sbjct: 331 AFLTMLPRLEILDLSFNYIK-------GSYPQHINISRNFSKLLSLRALHLRGY-VFQEL 382
Query: 269 KISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPR 327
+ + PL LP L T+ L ++ I+++ + N S L + L+ N++ L +
Sbjct: 383 REDDFQPL-------MQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVK 435
Query: 328 SVLRGQTQLTS 338
+ +S
Sbjct: 436 DTRQSYANSSS 446
>BC050445-1|AAH50445.1| 582|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 582
Score = 68.1 bits (159), Expect = 5e-11
Identities = 65/232 (28%), Positives = 101/232 (43%), Gaps = 8/232 (3%)
Query: 140 RSLPKLTHFR-LNAGRN--ITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQL 196
RSL K + LN N TL ++ ++ L L L+ + P + + L
Sbjct: 301 RSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSL 360
Query: 197 NVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDS 256
N+ N I I G F ++ L++ N++ +LP F + ++ L + N +
Sbjct: 361 NMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLD-FGTWTSMVELNLATNQLTKIP- 418
Query: 257 ETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLS 316
E GL ++ + +SNN+ L + NL LR L L+ + + LP E L+ L
Sbjct: 419 EDVSGLVSLEVLILSNNLLKKLPHGL-GNLRKLRELDLEENKLESLPNEIAYLKDLQKLV 477
Query: 317 LARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
L NQL LPR + T LT L L N + L PE L LE ++ N
Sbjct: 478 LTNNQLTTLPRGI-GHLTNLTHLGLGENLLTHL-PEEIGTLENLEELYLNDN 527
Score = 64.5 bits (150), Expect = 6e-10
Identities = 61/241 (25%), Positives = 110/241 (45%), Gaps = 8/241 (3%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
K +I+ L + + +T L +++ Q+ +P +V L L L+ ++T +
Sbjct: 109 KRSIHILPSSIKELTQLTELYLYSNKLQS-LPAEV-GCLVNLMTLALSEN-SLTSLPDSL 165
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
N L+ L+L K+ +P + L+ L L + N I + + L +++LS+
Sbjct: 166 DNLKKLRMLDLRHNKLREIPSVVYR-LDSLTTLYLRFNRITTVEKD-IKNLSKLSMLSIR 223
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
+N+I+ LPA + L+ L + N +L E I + + +N L L + +
Sbjct: 224 ENKIKQLPAEI-GELCNLITLDVAHNQLEHLPKE-IGNCTQITNLDLQHNELLDLPDTI- 280
Query: 284 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
NL +L L L + + +P S L L+L N + LP S+L +L SLTL+
Sbjct: 281 GNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLAR 340
Query: 344 N 344
N
Sbjct: 341 N 341
Score = 31.1 bits (67), Expect = 7.1
Identities = 33/105 (31%), Positives = 50/105 (47%), Gaps = 6/105 (5%)
Query: 291 TLQLDLS--SIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
+++LDLS SI LP + L L L N+L+ LP V L +L LS N++
Sbjct: 102 SMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEV-GCLVNLMTLALSENSLTS 160
Query: 349 LAPELFADLRALETFVMDGNELQ--VGYVYIDDILVAGHTRVSMI 391
L P+ +L+ L + N+L+ VY D L + R + I
Sbjct: 161 L-PDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRI 204
>BC003193-1|AAH03193.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 68.1 bits (159), Expect = 5e-11
Identities = 66/232 (28%), Positives = 108/232 (46%), Gaps = 9/232 (3%)
Query: 141 SLPKLTHFRLNAGRNITLHA--NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
S P+L + + +I+L + N L LEL + +T LPD + L LE+L++
Sbjct: 123 SFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPD-SLTQLRRLEELDL 181
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET 258
NEI N+ LH + L L+ N++ LP + + LL L + N L E
Sbjct: 182 GNNEIYNLPESIGALLH-LKDLWLDGNQLSELPQEI-GNLKNLLCLDVSENRLERLPEE- 238
Query: 259 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLA 318
GL + ++ IS N+ T+ + + L L L++D + + +LPE L L L
Sbjct: 239 ISGLTSLTDLVISQNLLETIPDGI-GKLKKLSILKVDQNRLTQLPEAVGECESLTELVLT 297
Query: 319 RNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
NQL LP+S+ + +L++L N + L P+ +L F + N L
Sbjct: 298 ENQLLTLPKSIGK-LKKLSNLNADRNKLVSL-PKEIGGCCSLTVFCVRDNRL 347
Score = 57.2 bits (132), Expect = 9e-08
Identities = 56/192 (29%), Positives = 88/192 (45%), Gaps = 6/192 (3%)
Query: 179 ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFAST 238
+ +P++ + LE+L + N++ + F+ L + L L+ N IQ LP + A+
Sbjct: 24 LVYVPEEIYRYARSLEELLLDANQLRELPEQFFQ-LVKLRKLGLSDNEIQRLPPEI-ANF 81
Query: 239 PRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSS 298
+L+ L + RN + E+ +Q S N PLT F L L L ++ S
Sbjct: 82 MQLVELDVSRNEIPEIP-ESISFCKALQVADFSGN-PLTRLPESFPELQNLTCLSVNDIS 139
Query: 299 IRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 358
++ LPE + L +L L N L LP S L +L L L N + L PE L
Sbjct: 140 LQSLPENIGNLYNLASLELRENLLTYLPDS-LTQLRRLEELDLGNNEIYNL-PESIGALL 197
Query: 359 ALETFVMDGNEL 370
L+ +DGN+L
Sbjct: 198 HLKDLWLDGNQL 209
Score = 52.8 bits (121), Expect = 2e-06
Identities = 33/107 (30%), Positives = 55/107 (51%), Gaps = 2/107 (1%)
Query: 264 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 323
H++ I + + + E ++ +L L LD + +RELPE+F LR L L+ N+++
Sbjct: 13 HVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQ 72
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
LP + QL L +S N + E+ PE + +AL+ GN L
Sbjct: 73 RLPPEIANFM-QLVELDVSRNEIPEI-PESISFCKALQVADFSGNPL 117
>AY358296-1|AAQ88663.1| 1041|Homo sapiens TLR8 protein.
Length = 1041
Score = 68.1 bits (159), Expect = 5e-11
Identities = 73/274 (26%), Positives = 120/274 (43%), Gaps = 15/274 (5%)
Query: 82 SLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRS 141
+LP ++CL + A V+ + + + L L NA A T + +
Sbjct: 503 NLPDIACL--NLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLD 560
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL-------E 194
L +H+ AG +T H N LK L LS I L D L L
Sbjct: 561 LSYNSHYFRIAG--VTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGN 618
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTP-RLLNLTMMRNSFRY 253
+L++ N+ N F+GL N+T L L+ NR++ +P F + P L L + N ++
Sbjct: 619 RLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKF 678
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPL 312
+ + ++ + + N L L +++ +LRTL L + I LP F+S S L
Sbjct: 679 FNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSL 738
Query: 313 RTLSLARNQLRVLPRSVL--RGQTQLTSLTLSYN 344
+ L L+ N L+ + +S L + T+L+ L L N
Sbjct: 739 KHLDLSSNLLKTINKSALETKTTTKLSMLELHGN 772
Score = 59.7 bits (138), Expect = 2e-08
Identities = 54/194 (27%), Positives = 92/194 (47%), Gaps = 26/194 (13%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIA--------------NITAGAFRGLHNV 217
L+LSD IT + +++F GL L ++N+ N NIT GAF L N+
Sbjct: 68 LDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFLNLKNL 127
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV--- 274
L L N++ +P+GL S L L++++N+ + E L +++ + ++ N
Sbjct: 128 RELLLEDNQLPQIPSGLPES---LTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFN 184
Query: 275 ----PLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVL 330
+++ VF L L L L +S+ +P + S+ LR L L+ Q++ +
Sbjct: 185 KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSS--LRKLFLSNTQIKYISEEDF 242
Query: 331 RGQTQLTSLTLSYN 344
+G LT L LS N
Sbjct: 243 KGLINLTLLDLSGN 256
Score = 56.0 bits (129), Expect = 2e-07
Identities = 62/247 (25%), Positives = 109/247 (44%), Gaps = 16/247 (6%)
Query: 141 SLPKLTHFRLNAGRNI-TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
+LP + L+A N L F+ P +KYL+L++ ++ A L+ LE L++
Sbjct: 503 NLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLS 562
Query: 200 ENE----IANITAGA--FRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
N IA +T + N+ VL+L+ N I L + L+ L N
Sbjct: 563 YNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDI 622
Query: 254 L--DSET-----FRGLDHIQEIKISNNVPLTLKEAVFSNLPA-LRTLQLDLSSIRELPEE 305
L D + F+GL ++ + +S N + F NLPA L L ++ + ++
Sbjct: 623 LWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWT 682
Query: 306 FISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 364
+ P L L L N+L L S+ + L +L LS+N ++ L +++ +L+
Sbjct: 683 LLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLD 742
Query: 365 MDGNELQ 371
+ N L+
Sbjct: 743 LSSNLLK 749
Score = 51.6 bits (118), Expect = 5e-06
Identities = 47/171 (27%), Positives = 76/171 (44%), Gaps = 23/171 (13%)
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG 261
E NI G F L N+ +LSL+ N + +P L +S L L + +Y+ E F+G
Sbjct: 188 EKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSS---LRKLFLSNTQIKYISEEDFKG 244
Query: 262 LDHIQEIKISNNVP-----------------LTLKEAVFSNLPALRTLQLDLSSIRELPE 304
L ++ + +S N P + + F NL LR L L +S+R++
Sbjct: 245 LINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINA 304
Query: 305 EFISNSP-LRTLSLARNQL--RVLPRSVLRGQTQLTSLTLSYNAVAELAPE 352
+ N P L+ L L N L ++ + L +L L LS+N + P+
Sbjct: 305 AWFKNMPHLKVLDLEFNYLVGEIVSGAFLTMLPRLEILDLSFNYIKGSYPQ 355
Score = 39.5 bits (88), Expect = 0.020
Identities = 55/197 (27%), Positives = 94/197 (47%), Gaps = 26/197 (13%)
Query: 173 ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
E S+ ++ +P +G V E L++ +N I +IT +F+GL N+T ++LN N
Sbjct: 48 ECSNRRLQEVPQT--VGKYVTE-LDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQN 104
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLP-ALRT 291
G N + N D F L +++E+ + +N L + + S LP +L
Sbjct: 105 G---------NPGIQSNGLNITDG-AFLNLKNLRELLLEDN---QLPQ-IPSGLPESLTE 150
Query: 292 LQLDLSSIRELPEEFISN-SPLRTLSLARN-------QLRVLPRSVLRGQTQLTSLTLSY 343
L L ++I + +E IS L+ L LA N + + V T L L+LS+
Sbjct: 151 LSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSF 210
Query: 344 NAVAELAPELFADLRAL 360
N+++ + P+L + LR L
Sbjct: 211 NSLSHVPPKLPSSLRKL 227
Score = 35.5 bits (78), Expect = 0.33
Identities = 45/191 (23%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Query: 151 NAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENE-IANITAG 209
+ G +I + F N L+YL LS + + F + L+ L++ N + I +G
Sbjct: 271 DGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIVSG 330
Query: 210 AF-RGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEI 268
AF L + +L L+ N I+ S P+ +N++ + L + RG QE+
Sbjct: 331 AFLTMLPRLEILDLSFNYIK-------GSYPQHINISRNFSKLLSLRALHLRGY-VFQEL 382
Query: 269 KISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPR 327
+ + PL LP L T+ L ++ I+++ + N S L + L+ N++ L +
Sbjct: 383 REDDFQPL-------MQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVK 435
Query: 328 SVLRGQTQLTS 338
+ +S
Sbjct: 436 DTRQSYANSSS 446
>AL513211-1|CAI17358.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 68.1 bits (159), Expect = 5e-11
Identities = 66/232 (28%), Positives = 108/232 (46%), Gaps = 9/232 (3%)
Query: 141 SLPKLTHFRLNAGRNITLHA--NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
S P+L + + +I+L + N L LEL + +T LPD + L LE+L++
Sbjct: 123 SFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPD-SLTQLRRLEELDL 181
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET 258
NEI N+ LH + L L+ N++ LP + + LL L + N L E
Sbjct: 182 GNNEIYNLPESIGALLH-LKDLWLDGNQLSELPQEI-GNLKNLLCLDVSENRLERLPEE- 238
Query: 259 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLA 318
GL + ++ IS N+ T+ + + L L L++D + + +LPE L L L
Sbjct: 239 ISGLTSLTDLVISQNLLETIPDGI-GKLKKLSILKVDQNRLTQLPEAVGECESLTELVLT 297
Query: 319 RNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
NQL LP+S+ + +L++L N + L P+ +L F + N L
Sbjct: 298 ENQLLTLPKSIGK-LKKLSNLNADRNKLVSL-PKEIGGCCSLTVFCVRDNRL 347
Score = 57.2 bits (132), Expect = 9e-08
Identities = 56/192 (29%), Positives = 88/192 (45%), Gaps = 6/192 (3%)
Query: 179 ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFAST 238
+ +P++ + LE+L + N++ + F+ L + L L+ N IQ LP + A+
Sbjct: 24 LVYVPEEIYRYARSLEELLLDANQLRELPEQFFQ-LVKLRKLGLSDNEIQRLPPEI-ANF 81
Query: 239 PRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSS 298
+L+ L + RN + E+ +Q S N PLT F L L L ++ S
Sbjct: 82 MQLVELDVSRNEIPEIP-ESISFCKALQVADFSGN-PLTRLPESFPELQNLTCLSVNDIS 139
Query: 299 IRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 358
++ LPE + L +L L N L LP S L +L L L N + L PE L
Sbjct: 140 LQSLPENIGNLYNLASLELRENLLTYLPDS-LTQLRRLEELDLGNNEIYNL-PESIGALL 197
Query: 359 ALETFVMDGNEL 370
L+ +DGN+L
Sbjct: 198 HLKDLWLDGNQL 209
Score = 52.8 bits (121), Expect = 2e-06
Identities = 33/107 (30%), Positives = 55/107 (51%), Gaps = 2/107 (1%)
Query: 264 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 323
H++ I + + + E ++ +L L LD + +RELPE+F LR L L+ N+++
Sbjct: 13 HVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQ 72
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
LP + QL L +S N + E+ PE + +AL+ GN L
Sbjct: 73 RLPPEIANFM-QLVELDVSRNEIPEI-PESISFCKALQVADFSGNPL 117
>AL158163-3|CAH72813.1| 372|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 372
Score = 68.1 bits (159), Expect = 5e-11
Identities = 65/232 (28%), Positives = 101/232 (43%), Gaps = 8/232 (3%)
Query: 140 RSLPKLTHFR-LNAGRN--ITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQL 196
RSL K + LN N TL ++ ++ L L L+ + P + + L
Sbjct: 91 RSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSL 150
Query: 197 NVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDS 256
N+ N I I G F ++ L++ N++ +LP F + ++ L + N +
Sbjct: 151 NMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLD-FGTWTSMVELNLATNQLTKIP- 208
Query: 257 ETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLS 316
E GL ++ + +SNN+ L + NL LR L L+ + + LP E L+ L
Sbjct: 209 EDVSGLVSLEVLILSNNLLKKLPHGL-GNLRKLRELDLEENKLESLPNEIAYLKDLQKLV 267
Query: 317 LARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
L NQL LPR + T LT L L N + L PE L LE ++ N
Sbjct: 268 LTNNQLTTLPRGI-GHLTNLTHLGLGENLLTHL-PEEIGTLENLEELYLNDN 317
Score = 47.6 bits (108), Expect = 8e-05
Identities = 43/186 (23%), Positives = 85/186 (45%), Gaps = 5/186 (2%)
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
N L+ L+L K+ +P + L+ L L + N I + + L +++LS+ +
Sbjct: 3 NLKKLRMLDLRHNKLREIPSVVYR-LDSLTTLYLRFNRITTVEKD-IKNLSKLSMLSIRE 60
Query: 225 NRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFS 284
N+I+ LPA + + L L + N + + ++E+ + NN TL E++ S
Sbjct: 61 NKIKQLPAEI-GNLSSLSRLGLRYNRLSAI-PRSLAKCSALEELNLENNNISTLPESLLS 118
Query: 285 NLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+L L +L L + + P S S + +L++ N++ +P + L+ L +
Sbjct: 119 SLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKD 178
Query: 344 NAVAEL 349
N + L
Sbjct: 179 NQLTSL 184
>AL158163-2|CAH72812.1| 582|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 582
Score = 68.1 bits (159), Expect = 5e-11
Identities = 65/232 (28%), Positives = 101/232 (43%), Gaps = 8/232 (3%)
Query: 140 RSLPKLTHFR-LNAGRN--ITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQL 196
RSL K + LN N TL ++ ++ L L L+ + P + + L
Sbjct: 301 RSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSL 360
Query: 197 NVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDS 256
N+ N I I G F ++ L++ N++ +LP F + ++ L + N +
Sbjct: 361 NMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLD-FGTWTSMVELNLATNQLTKIP- 418
Query: 257 ETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLS 316
E GL ++ + +SNN+ L + NL LR L L+ + + LP E L+ L
Sbjct: 419 EDVSGLVSLEVLILSNNLLKKLPHGL-GNLRKLRELDLEENKLESLPNEIAYLKDLQKLV 477
Query: 317 LARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
L NQL LPR + T LT L L N + L PE L LE ++ N
Sbjct: 478 LTNNQLTTLPRGI-GHLTNLTHLGLGENLLTHL-PEEIGTLENLEELYLNDN 527
Score = 64.5 bits (150), Expect = 6e-10
Identities = 61/241 (25%), Positives = 110/241 (45%), Gaps = 8/241 (3%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
K +I+ L + + +T L +++ Q+ +P +V L L L+ ++T +
Sbjct: 109 KRSIHILPSSIKELTQLTELYLYSNKLQS-LPAEV-GCLVNLMTLALSEN-SLTSLPDSL 165
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
N L+ L+L K+ +P + L+ L L + N I + + L +++LS+
Sbjct: 166 DNLKKLRMLDLRHNKLREIPSVVYR-LDSLTTLYLRFNRITTVEKD-IKNLSKLSMLSIR 223
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
+N+I+ LPA + L+ L + N +L E I + + +N L L + +
Sbjct: 224 ENKIKQLPAEI-GELCNLITLDVAHNQLEHLPKE-IGNCTQITNLDLQHNELLDLPDTI- 280
Query: 284 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
NL +L L L + + +P S L L+L N + LP S+L +L SLTL+
Sbjct: 281 GNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLAR 340
Query: 344 N 344
N
Sbjct: 341 N 341
Score = 31.1 bits (67), Expect = 7.1
Identities = 33/105 (31%), Positives = 50/105 (47%), Gaps = 6/105 (5%)
Query: 291 TLQLDLS--SIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
+++LDLS SI LP + L L L N+L+ LP V L +L LS N++
Sbjct: 102 SMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEV-GCLVNLMTLALSENSLTS 160
Query: 349 LAPELFADLRALETFVMDGNELQ--VGYVYIDDILVAGHTRVSMI 391
L P+ +L+ L + N+L+ VY D L + R + I
Sbjct: 161 L-PDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRI 204
>AL033384-1|CAI21666.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 68.1 bits (159), Expect = 5e-11
Identities = 66/232 (28%), Positives = 108/232 (46%), Gaps = 9/232 (3%)
Query: 141 SLPKLTHFRLNAGRNITLHA--NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
S P+L + + +I+L + N L LEL + +T LPD + L LE+L++
Sbjct: 123 SFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPD-SLTQLRRLEELDL 181
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET 258
NEI N+ LH + L L+ N++ LP + + LL L + N L E
Sbjct: 182 GNNEIYNLPESIGALLH-LKDLWLDGNQLSELPQEI-GNLKNLLCLDVSENRLERLPEE- 238
Query: 259 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLA 318
GL + ++ IS N+ T+ + + L L L++D + + +LPE L L L
Sbjct: 239 ISGLTSLTDLVISQNLLETIPDGI-GKLKKLSILKVDQNRLTQLPEAVGECESLTELVLT 297
Query: 319 RNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
NQL LP+S+ + +L++L N + L P+ +L F + N L
Sbjct: 298 ENQLLTLPKSIGK-LKKLSNLNADRNKLVSL-PKEIGGCCSLTVFCVRDNRL 347
Score = 57.2 bits (132), Expect = 9e-08
Identities = 56/192 (29%), Positives = 88/192 (45%), Gaps = 6/192 (3%)
Query: 179 ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFAST 238
+ +P++ + LE+L + N++ + F+ L + L L+ N IQ LP + A+
Sbjct: 24 LVYVPEEIYRYARSLEELLLDANQLRELPEQFFQ-LVKLRKLGLSDNEIQRLPPEI-ANF 81
Query: 239 PRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSS 298
+L+ L + RN + E+ +Q S N PLT F L L L ++ S
Sbjct: 82 MQLVELDVSRNEIPEIP-ESISFCKALQVADFSGN-PLTRLPESFPELQNLTCLSVNDIS 139
Query: 299 IRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 358
++ LPE + L +L L N L LP S L +L L L N + L PE L
Sbjct: 140 LQSLPENIGNLYNLASLELRENLLTYLPDS-LTQLRRLEELDLGNNEIYNL-PESIGALL 197
Query: 359 ALETFVMDGNEL 370
L+ +DGN+L
Sbjct: 198 HLKDLWLDGNQL 209
Score = 52.8 bits (121), Expect = 2e-06
Identities = 33/107 (30%), Positives = 55/107 (51%), Gaps = 2/107 (1%)
Query: 264 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 323
H++ I + + + E ++ +L L LD + +RELPE+F LR L L+ N+++
Sbjct: 13 HVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQ 72
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
LP + QL L +S N + E+ PE + +AL+ GN L
Sbjct: 73 RLPPEIANFM-QLVELDVSRNEIPEI-PESISFCKALQVADFSGNPL 117
>AF359380-1|AAK72246.1| 524|Homo sapiens LANO adaptor protein
protein.
Length = 524
Score = 68.1 bits (159), Expect = 5e-11
Identities = 66/232 (28%), Positives = 108/232 (46%), Gaps = 9/232 (3%)
Query: 141 SLPKLTHFRLNAGRNITLHA--NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
S P+L + + +I+L + N L LEL + +T LPD + L LE+L++
Sbjct: 123 SFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPD-SLTQLRRLEELDL 181
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET 258
NEI N+ LH + L L+ N++ LP + + LL L + N L E
Sbjct: 182 GNNEIYNLPESIGALLH-LKDLWLDGNQLSELPQEI-GNLKNLLCLDVSENRLERLPEE- 238
Query: 259 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLA 318
GL + ++ IS N+ T+ + + L L L++D + + +LPE L L L
Sbjct: 239 ISGLTSLTDLVISQNLLETIPDGI-GKLKKLSILKVDQNRLTQLPEAVGECESLTELVLT 297
Query: 319 RNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
NQL LP+S+ + +L++L N + L P+ +L F + N L
Sbjct: 298 ENQLLTLPKSIGK-LKKLSNLNADRNKLVSL-PKEIGGCCSLTVFCVRDNRL 347
Score = 57.2 bits (132), Expect = 9e-08
Identities = 56/192 (29%), Positives = 88/192 (45%), Gaps = 6/192 (3%)
Query: 179 ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFAST 238
+ +P++ + LE+L + N++ + F+ L + L L+ N IQ LP + A+
Sbjct: 24 LVYVPEEIYRYARSLEELLLDANQLRELPEQFFQ-LVKLRKLGLSDNEIQRLPPEI-ANF 81
Query: 239 PRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSS 298
+L+ L + RN + E+ +Q S N PLT F L L L ++ S
Sbjct: 82 MQLVELDVSRNEIPEIP-ESISFCKALQVADFSGN-PLTRLPESFPELQNLTCLSVNDIS 139
Query: 299 IRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 358
++ LPE + L +L L N L LP S L +L L L N + L PE L
Sbjct: 140 LQSLPENIGNLYNLASLELRENLLTYLPDS-LTQLRRLEELDLGNNEIYNL-PESIGALL 197
Query: 359 ALETFVMDGNEL 370
L+ +DGN+L
Sbjct: 198 HLKDLWLDGNQL 209
Score = 52.8 bits (121), Expect = 2e-06
Identities = 33/107 (30%), Positives = 55/107 (51%), Gaps = 2/107 (1%)
Query: 264 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 323
H++ I + + + E ++ +L L LD + +RELPE+F LR L L+ N+++
Sbjct: 13 HVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQ 72
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
LP + QL L +S N + E+ PE + +AL+ GN L
Sbjct: 73 RLPPEIANFM-QLVELDVSRNEIPEI-PESISFCKALQVADFSGNPL 117
>AF332199-1|AAK69623.1| 524|Homo sapiens leucine-rich repeats
protein protein.
Length = 524
Score = 68.1 bits (159), Expect = 5e-11
Identities = 66/232 (28%), Positives = 108/232 (46%), Gaps = 9/232 (3%)
Query: 141 SLPKLTHFRLNAGRNITLHA--NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
S P+L + + +I+L + N L LEL + +T LPD + L LE+L++
Sbjct: 123 SFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPD-SLTQLRRLEELDL 181
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET 258
NEI N+ LH + L L+ N++ LP + + LL L + N L E
Sbjct: 182 GNNEIYNLPESIGALLH-LKDLWLDGNQLSELPQEI-GNLKNLLCLDVSENRLERLPEE- 238
Query: 259 FRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLA 318
GL + ++ IS N+ T+ + + L L L++D + + +LPE L L L
Sbjct: 239 ISGLTSLTDLVISQNLLETIPDGI-GKLKKLSILKVDQNRLTQLPEAVGECESLTELVLT 297
Query: 319 RNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
NQL LP+S+ + +L++L N + L P+ +L F + N L
Sbjct: 298 ENQLLTLPKSIGK-LKKLSNLNADRNKLVSL-PKEIGGCCSLTVFCVRDNRL 347
Score = 57.2 bits (132), Expect = 9e-08
Identities = 56/192 (29%), Positives = 88/192 (45%), Gaps = 6/192 (3%)
Query: 179 ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFAST 238
+ +P++ + LE+L + N++ + F+ L + L L+ N IQ LP + A+
Sbjct: 24 LVYVPEEIYRYARSLEELLLDANQLRELPEQFFQ-LVKLRKLGLSDNEIQRLPPEI-ANF 81
Query: 239 PRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSS 298
+L+ L + RN + E+ +Q S N PLT F L L L ++ S
Sbjct: 82 MQLVELDVSRNEIPEIP-ESISFCKALQVADFSGN-PLTRLPESFPELQNLTCLSVNDIS 139
Query: 299 IRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 358
++ LPE + L +L L N L LP S L +L L L N + L PE L
Sbjct: 140 LQSLPENIGNLYNLASLELRENLLTYLPDS-LTQLRRLEELDLGNNEIYNL-PESIGALL 197
Query: 359 ALETFVMDGNEL 370
L+ +DGN+L
Sbjct: 198 HLKDLWLDGNQL 209
Score = 52.8 bits (121), Expect = 2e-06
Identities = 33/107 (30%), Positives = 55/107 (51%), Gaps = 2/107 (1%)
Query: 264 HIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLR 323
H++ I + + + E ++ +L L LD + +RELPE+F LR L L+ N+++
Sbjct: 13 HVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQ 72
Query: 324 VLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
LP + QL L +S N + E+ PE + +AL+ GN L
Sbjct: 73 RLPPEIANFM-QLVELDVSRNEIPEI-PESISFCKALQVADFSGNPL 117
>AF246971-1|AAF64061.1| 1059|Homo sapiens Toll-like receptor 8
protein.
Length = 1059
Score = 68.1 bits (159), Expect = 5e-11
Identities = 73/274 (26%), Positives = 120/274 (43%), Gaps = 15/274 (5%)
Query: 82 SLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRS 141
+LP ++CL + A V+ + + + L L NA A T + +
Sbjct: 521 NLPDIACL--NLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLD 578
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL-------E 194
L +H+ AG +T H N LK L LS I L D L L
Sbjct: 579 LSYNSHYFRIAG--VTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGN 636
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTP-RLLNLTMMRNSFRY 253
+L++ N+ N F+GL N+T L L+ NR++ +P F + P L L + N ++
Sbjct: 637 RLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKF 696
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPL 312
+ + ++ + + N L L +++ +LRTL L + I LP F+S S L
Sbjct: 697 FNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSL 756
Query: 313 RTLSLARNQLRVLPRSVL--RGQTQLTSLTLSYN 344
+ L L+ N L+ + +S L + T+L+ L L N
Sbjct: 757 KHLDLSSNLLKTINKSALETKTTTKLSMLELHGN 790
Score = 56.4 bits (130), Expect = 2e-07
Identities = 53/194 (27%), Positives = 91/194 (46%), Gaps = 26/194 (13%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIA--------------NITAGAFRGLHNV 217
L+LSD IT + +++F GL L ++N+ N NIT GAF L N+
Sbjct: 86 LDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFLNLKNL 145
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV--- 274
L L N++ +P+GL S L L++++N+ + E L +++ + ++ N
Sbjct: 146 RELLLEDNQLPQIPSGLPES---LTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFN 202
Query: 275 ----PLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVL 330
+++ VF L L L L +S+ + + S+ LR L L+ Q++ +
Sbjct: 203 KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVSPKLPSS--LRKLFLSNTQIKYISEEDF 260
Query: 331 RGQTQLTSLTLSYN 344
+G LT L LS N
Sbjct: 261 KGLINLTLLDLSGN 274
Score = 56.0 bits (129), Expect = 2e-07
Identities = 62/247 (25%), Positives = 109/247 (44%), Gaps = 16/247 (6%)
Query: 141 SLPKLTHFRLNAGRNI-TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
+LP + L+A N L F+ P +KYL+L++ ++ A L+ LE L++
Sbjct: 521 NLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLS 580
Query: 200 ENE----IANITAGA--FRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
N IA +T + N+ VL+L+ N I L + L+ L N
Sbjct: 581 YNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDI 640
Query: 254 L--DSET-----FRGLDHIQEIKISNNVPLTLKEAVFSNLPA-LRTLQLDLSSIRELPEE 305
L D + F+GL ++ + +S N + F NLPA L L ++ + ++
Sbjct: 641 LWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWT 700
Query: 306 FISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 364
+ P L L L N+L L S+ + L +L LS+N ++ L +++ +L+
Sbjct: 701 LLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLD 760
Query: 365 MDGNELQ 371
+ N L+
Sbjct: 761 LSSNLLK 767
Score = 47.6 bits (108), Expect = 8e-05
Identities = 46/171 (26%), Positives = 74/171 (43%), Gaps = 23/171 (13%)
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG 261
E NI G F L N+ +LSL+ N + + L +S L L + +Y+ E F+G
Sbjct: 206 EKTNIEDGVFETLTNLELLSLSFNSLSHVSPKLPSS---LRKLFLSNTQIKYISEEDFKG 262
Query: 262 LDHIQEIKISNNVP-----------------LTLKEAVFSNLPALRTLQLDLSSIRELPE 304
L ++ + +S N P + + F NL LR L L +S+R++
Sbjct: 263 LINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINA 322
Query: 305 EFISNSP-LRTLSLARNQL--RVLPRSVLRGQTQLTSLTLSYNAVAELAPE 352
+ N P L+ L L N L + + L +L L LS+N + P+
Sbjct: 323 AWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQ 373
Score = 40.3 bits (90), Expect = 0.012
Identities = 55/197 (27%), Positives = 95/197 (48%), Gaps = 26/197 (13%)
Query: 173 ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
E S+ ++ +P +G V E L++ +N I +IT +F+GL N+T ++LN N
Sbjct: 66 ECSNRRLQEVPQT--VGKYVTE-LDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQN 122
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLP-ALRT 291
G N + N D F L +++E+ + +N L + + S LP +L
Sbjct: 123 G---------NPGIQSNGLNITDG-AFLNLKNLRELLLEDN---QLPQ-IPSGLPESLTE 168
Query: 292 LQLDLSSIRELPEEFISN-SPLRTLSLARN-------QLRVLPRSVLRGQTQLTSLTLSY 343
L L ++I + +E IS L+ L LA N + + V T L L+LS+
Sbjct: 169 LSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSF 228
Query: 344 NAVAELAPELFADLRAL 360
N+++ ++P+L + LR L
Sbjct: 229 NSLSHVSPKLPSSLRKL 245
Score = 34.7 bits (76), Expect = 0.58
Identities = 66/285 (23%), Positives = 119/285 (41%), Gaps = 28/285 (9%)
Query: 58 VCAEFPEIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKG 117
VC E I+ L +L L S LS + K+ + K + I ++ + FKG
Sbjct: 204 VC-EKTNIEDGVFETLTNLELLSLSFNSLSHVSPKLPSSLRKLFLSNTQIKYISEEDFKG 262
Query: 118 LGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDA 177
L I ++ +G P P + + G +I + F N L+YL LS
Sbjct: 263 L-INLTLLDLSG---NCPRCFNAPFPCVP---CDGGASINIDRFAFQNLTQLRYLNLSST 315
Query: 178 KITVLPDDAFLGLNVLEQLNVWENE-IANITAGAF-RGLHNVTVLSLNKNRIQALPAGLF 235
+ + F + L+ L++ N + I +GAF L + +L L+ N I+
Sbjct: 316 SLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIK------- 368
Query: 236 ASTPRLLNLTMMRNSFRYLDSETFRGLDHI-QEIKISNNVPLTLKEAVFSNLPALRTLQL 294
S P+ +N++ RN + L ++ QE++ + PL LP L T+ L
Sbjct: 369 GSYPQHINIS--RNFSKPLSLRALHLRGYVFQELREDDFQPL-------MQLPNLSTINL 419
Query: 295 DLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTS 338
++ I+++ + N S L + L+ N++ L + + +S
Sbjct: 420 GINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKDTRQSYANSSS 464
>AF245703-1|AAF78036.1| 1041|Homo sapiens toll-like receptor 8
protein.
Length = 1041
Score = 68.1 bits (159), Expect = 5e-11
Identities = 73/274 (26%), Positives = 120/274 (43%), Gaps = 15/274 (5%)
Query: 82 SLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRS 141
+LP ++CL + A V+ + + + L L NA A T + +
Sbjct: 503 NLPDIACL--NLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLD 560
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVL-------E 194
L +H+ AG +T H N LK L LS I L D L L
Sbjct: 561 LSYNSHYFRIAG--VTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGN 618
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTP-RLLNLTMMRNSFRY 253
+L++ N+ N F+GL N+T L L+ NR++ +P F + P L L + N ++
Sbjct: 619 RLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKF 678
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPL 312
+ + ++ + + N L L +++ +LRTL L + I LP F+S S L
Sbjct: 679 FNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSL 738
Query: 313 RTLSLARNQLRVLPRSVL--RGQTQLTSLTLSYN 344
+ L L+ N L+ + +S L + T+L+ L L N
Sbjct: 739 KHLDLSSNLLKTINKSALETKTTTKLSMLELHGN 772
Score = 59.7 bits (138), Expect = 2e-08
Identities = 54/194 (27%), Positives = 92/194 (47%), Gaps = 26/194 (13%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIA--------------NITAGAFRGLHNV 217
L+LSD IT + +++F GL L ++N+ N NIT GAF L N+
Sbjct: 68 LDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFLNLKNL 127
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNV--- 274
L L N++ +P+GL S L L++++N+ + E L +++ + ++ N
Sbjct: 128 RELLLEDNQLPQIPSGLPES---LTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFN 184
Query: 275 ----PLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVL 330
+++ VF L L L L +S+ +P + S+ LR L L+ Q++ +
Sbjct: 185 KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSS--LRKLFLSNTQIKYISEEDF 242
Query: 331 RGQTQLTSLTLSYN 344
+G LT L LS N
Sbjct: 243 KGLINLTLLDLSGN 256
Score = 56.0 bits (129), Expect = 2e-07
Identities = 62/247 (25%), Positives = 109/247 (44%), Gaps = 16/247 (6%)
Query: 141 SLPKLTHFRLNAGRNI-TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
+LP + L+A N L F+ P +KYL+L++ ++ A L+ LE L++
Sbjct: 503 NLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLS 562
Query: 200 ENE----IANITAGA--FRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
N IA +T + N+ VL+L+ N I L + L+ L N
Sbjct: 563 YNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDI 622
Query: 254 L--DSET-----FRGLDHIQEIKISNNVPLTLKEAVFSNLPA-LRTLQLDLSSIRELPEE 305
L D + F+GL ++ + +S N + F NLPA L L ++ + ++
Sbjct: 623 LWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWT 682
Query: 306 FISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFV 364
+ P L L L N+L L S+ + L +L LS+N ++ L +++ +L+
Sbjct: 683 LLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLD 742
Query: 365 MDGNELQ 371
+ N L+
Sbjct: 743 LSSNLLK 749
Score = 50.8 bits (116), Expect = 8e-06
Identities = 47/171 (27%), Positives = 75/171 (43%), Gaps = 23/171 (13%)
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG 261
E NI G F L N+ +LSL+ N + +P L +S L L + +Y+ E F+G
Sbjct: 188 EKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSS---LRKLFLSNTQIKYISEEDFKG 244
Query: 262 LDHIQEIKISNNVP-----------------LTLKEAVFSNLPALRTLQLDLSSIRELPE 304
L ++ + +S N P + + F NL LR L L +S+R++
Sbjct: 245 LINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINA 304
Query: 305 EFISNSP-LRTLSLARNQL--RVLPRSVLRGQTQLTSLTLSYNAVAELAPE 352
+ N P L+ L L N L + + L +L L LS+N + P+
Sbjct: 305 AWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQ 355
Score = 39.5 bits (88), Expect = 0.020
Identities = 55/197 (27%), Positives = 94/197 (47%), Gaps = 26/197 (13%)
Query: 173 ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
E S+ ++ +P +G V E L++ +N I +IT +F+GL N+T ++LN N
Sbjct: 48 ECSNRRLQEVPQT--VGKYVTE-LDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQN 104
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLP-ALRT 291
G N + N D F L +++E+ + +N L + + S LP +L
Sbjct: 105 G---------NPGIQSNGLNITDG-AFLNLKNLRELLLEDN---QLPQ-IPSGLPESLTE 150
Query: 292 LQLDLSSIRELPEEFISN-SPLRTLSLARN-------QLRVLPRSVLRGQTQLTSLTLSY 343
L L ++I + +E IS L+ L LA N + + V T L L+LS+
Sbjct: 151 LSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSF 210
Query: 344 NAVAELAPELFADLRAL 360
N+++ + P+L + LR L
Sbjct: 211 NSLSHVPPKLPSSLRKL 227
Score = 35.5 bits (78), Expect = 0.33
Identities = 45/191 (23%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Query: 151 NAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENE-IANITAG 209
+ G +I + F N L+YL LS + + F + L+ L++ N + I +G
Sbjct: 271 DGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASG 330
Query: 210 AF-RGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEI 268
AF L + +L L+ N I+ S P+ +N++ + L + RG QE+
Sbjct: 331 AFLTMLPRLEILDLSFNYIK-------GSYPQHINISRNFSKLLSLRALHLRGY-VFQEL 382
Query: 269 KISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPR 327
+ + PL LP L T+ L ++ I+++ + N S L + L+ N++ L +
Sbjct: 383 REDDFQPL-------MQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVK 435
Query: 328 SVLRGQTQLTS 338
+ +S
Sbjct: 436 DTRQSYANSSS 446
>AF068920-1|AAC39856.1| 582|Homo sapiens Ras-binding protein SUR-8
protein.
Length = 582
Score = 68.1 bits (159), Expect = 5e-11
Identities = 65/232 (28%), Positives = 101/232 (43%), Gaps = 8/232 (3%)
Query: 140 RSLPKLTHFR-LNAGRN--ITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQL 196
RSL K + LN N TL ++ ++ L L L+ + P + + L
Sbjct: 301 RSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSL 360
Query: 197 NVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDS 256
N+ N I I G F ++ L++ N++ +LP F + ++ L + N +
Sbjct: 361 NMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLD-FGTWTSMVELNLATNQLTKIP- 418
Query: 257 ETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLS 316
E GL ++ + +SNN+ L + NL LR L L+ + + LP E L+ L
Sbjct: 419 EDVSGLVSLEVLILSNNLLKKLPHGL-GNLRKLRELDLEENKLESLPNEIAYLKDLQKLV 477
Query: 317 LARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
L NQL LPR + T LT L L N + L PE L LE ++ N
Sbjct: 478 LTNNQLTTLPRGI-GHLTNLTHLGLGENLLTHL-PEEIGTLENLEELYLNDN 527
Score = 64.5 bits (150), Expect = 6e-10
Identities = 61/241 (25%), Positives = 110/241 (45%), Gaps = 8/241 (3%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
K +I+ L + + +T L +++ Q+ +P +V L L L+ ++T +
Sbjct: 109 KRSIHILPSSIKELTQLTELYLYSNKLQS-LPAEV-GCLVNLMTLALSEN-SLTSLPDSL 165
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
N L+ L+L K+ +P + L+ L L + N I + + L +++LS+
Sbjct: 166 DNLKKLRMLDLRHNKLREIPSVVYR-LDSLTTLYLRFNRITTVEKD-IKNLSKLSMLSIR 223
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
+N+I+ LPA + L+ L + N +L E I + + +N L L + +
Sbjct: 224 ENKIKQLPAEI-GELCNLITLDVAHNQLEHLPKE-IGNCTQITNLDLQHNELLDLPDTI- 280
Query: 284 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
NL +L L L + + +P S L L+L N + LP S+L +L SLTL+
Sbjct: 281 GNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLAR 340
Query: 344 N 344
N
Sbjct: 341 N 341
Score = 31.1 bits (67), Expect = 7.1
Identities = 33/105 (31%), Positives = 50/105 (47%), Gaps = 6/105 (5%)
Query: 291 TLQLDLS--SIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
+++LDLS SI LP + L L L N+L+ LP V L +L LS N++
Sbjct: 102 SMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEV-GCLVNLMTLALSENSLTS 160
Query: 349 LAPELFADLRALETFVMDGNELQ--VGYVYIDDILVAGHTRVSMI 391
L P+ +L+ L + N+L+ VY D L + R + I
Sbjct: 161 L-PDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRI 204
>AF054828-1|AAC25698.1| 582|Homo sapiens leucine-rich repeat
protein SHOC-2 protein.
Length = 582
Score = 68.1 bits (159), Expect = 5e-11
Identities = 65/232 (28%), Positives = 101/232 (43%), Gaps = 8/232 (3%)
Query: 140 RSLPKLTHFR-LNAGRN--ITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQL 196
RSL K + LN N TL ++ ++ L L L+ + P + + L
Sbjct: 301 RSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSL 360
Query: 197 NVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDS 256
N+ N I I G F ++ L++ N++ +LP F + ++ L + N +
Sbjct: 361 NMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLD-FGTWTSMVELNLATNQLTKIP- 418
Query: 257 ETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLS 316
E GL ++ + +SNN+ L + NL LR L L+ + + LP E L+ L
Sbjct: 419 EDVSGLVSLEVLILSNNLLKKLPHGL-GNLRKLRELDLEENKLESLPNEIAYLKDLQKLV 477
Query: 317 LARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
L NQL LPR + T LT L L N + L PE L LE ++ N
Sbjct: 478 LTNNQLTTLPRGI-GHLTNLTHLGLGENLLTHL-PEEIGTLENLEELYLNDN 527
Score = 64.5 bits (150), Expect = 6e-10
Identities = 61/241 (25%), Positives = 110/241 (45%), Gaps = 8/241 (3%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
K +I+ L + + +T L +++ Q+ +P +V L L L+ ++T +
Sbjct: 109 KRSIHILPSSIKELTQLTELYLYSNKLQS-LPAEV-GCLVNLMTLALSEN-SLTSLPDSL 165
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
N L+ L+L K+ +P + L+ L L + N I + + L +++LS+
Sbjct: 166 DNLKKLRMLDLRHNKLREIPSVVYR-LDSLTTLYLRFNRITTVEKD-IKNLSKLSMLSIR 223
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
+N+I+ LPA + L+ L + N +L E I + + +N L L + +
Sbjct: 224 ENKIKQLPAEI-GELCNLITLDVAHNQLEHLPKE-IGNCTQITNLDLQHNELLDLPDTI- 280
Query: 284 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
NL +L L L + + +P S L L+L N + LP S+L +L SLTL+
Sbjct: 281 GNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLAR 340
Query: 344 N 344
N
Sbjct: 341 N 341
Score = 31.1 bits (67), Expect = 7.1
Identities = 33/105 (31%), Positives = 50/105 (47%), Gaps = 6/105 (5%)
Query: 291 TLQLDLS--SIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
+++LDLS SI LP + L L L N+L+ LP V L +L LS N++
Sbjct: 102 SMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEV-GCLVNLMTLALSENSLTS 160
Query: 349 LAPELFADLRALETFVMDGNELQ--VGYVYIDDILVAGHTRVSMI 391
L P+ +L+ L + N+L+ VY D L + R + I
Sbjct: 161 L-PDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRI 204
>AB020669-1|BAA74885.2| 584|Homo sapiens KIAA0862 protein protein.
Length = 584
Score = 68.1 bits (159), Expect = 5e-11
Identities = 65/232 (28%), Positives = 101/232 (43%), Gaps = 8/232 (3%)
Query: 140 RSLPKLTHFR-LNAGRN--ITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQL 196
RSL K + LN N TL ++ ++ L L L+ + P + + L
Sbjct: 303 RSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSL 362
Query: 197 NVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDS 256
N+ N I I G F ++ L++ N++ +LP F + ++ L + N +
Sbjct: 363 NMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLD-FGTWTSMVELNLATNQLTKIP- 420
Query: 257 ETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLS 316
E GL ++ + +SNN+ L + NL LR L L+ + + LP E L+ L
Sbjct: 421 EDVSGLVSLEVLILSNNLLKKLPHGL-GNLRKLRELDLEENKLESLPNEIAYLKDLQKLV 479
Query: 317 LARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
L NQL LPR + T LT L L N + L PE L LE ++ N
Sbjct: 480 LTNNQLTTLPRGI-GHLTNLTHLGLGENLLTHL-PEEIGTLENLEELYLNDN 529
Score = 64.5 bits (150), Expect = 6e-10
Identities = 61/241 (25%), Positives = 110/241 (45%), Gaps = 8/241 (3%)
Query: 104 KNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
K +I+ L + + +T L +++ Q+ +P +V L L L+ ++T +
Sbjct: 111 KRSIHILPSSIKELTQLTELYLYSNKLQS-LPAEV-GCLVNLMTLALSEN-SLTSLPDSL 167
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
N L+ L+L K+ +P + L+ L L + N I + + L +++LS+
Sbjct: 168 DNLKKLRMLDLRHNKLREIPSVVYR-LDSLTTLYLRFNRITTVEKD-IKNLSKLSMLSIR 225
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
+N+I+ LPA + L+ L + N +L E I + + +N L L + +
Sbjct: 226 ENKIKQLPAEI-GELCNLITLDVAHNQLEHLPKE-IGNCTQITNLDLQHNELLDLPDTI- 282
Query: 284 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
NL +L L L + + +P S L L+L N + LP S+L +L SLTL+
Sbjct: 283 GNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLAR 342
Query: 344 N 344
N
Sbjct: 343 N 343
Score = 31.1 bits (67), Expect = 7.1
Identities = 33/105 (31%), Positives = 50/105 (47%), Gaps = 6/105 (5%)
Query: 291 TLQLDLS--SIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
+++LDLS SI LP + L L L N+L+ LP V L +L LS N++
Sbjct: 104 SMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEV-GCLVNLMTLALSENSLTS 162
Query: 349 LAPELFADLRALETFVMDGNELQ--VGYVYIDDILVAGHTRVSMI 391
L P+ +L+ L + N+L+ VY D L + R + I
Sbjct: 163 L-PDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRI 206
>AL356953-4|CAI15930.1| 828|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 828
Score = 67.7 bits (158), Expect = 7e-11
Identities = 73/283 (25%), Positives = 121/283 (42%), Gaps = 32/283 (11%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ + AF GL ++M +P + L LP L LN + +
Sbjct: 57 NHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLDLNYNK-LQEFPVAIR 115
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAF------------- 211
L+ L + I +P+ AF+G +L+ ++ ++N I + AF
Sbjct: 116 TLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNG 175
Query: 212 ----------RGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG 261
+G ++ +L+L + I+ LP+G+ PRL L + N L S
Sbjct: 176 AMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPS--LHR 233
Query: 262 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARN 320
++EI + +N + FS L +L+ L L ++IR + PE F + L L L N
Sbjct: 234 CQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDN 293
Query: 321 QLRVLPRSVLRGQTQLTSLTLSYN-AVAE-LAPELFADLRALE 361
QL LP + L G L L L N A+++ + + F LR LE
Sbjct: 294 QLTTLPLAGLGG---LMHLKLKGNLALSQAFSKDSFPKLRILE 333
Score = 66.1 bits (154), Expect = 2e-10
Identities = 53/200 (26%), Positives = 88/200 (44%), Gaps = 3/200 (1%)
Query: 173 ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
+LS +T L F L LE+L + N +++I AF GL+++ +L L N++ +PA
Sbjct: 29 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 88
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTL 292
P L +L + N + R L +QE+ NN + E F P L+T+
Sbjct: 89 EALWELPSLQSLDLNYNKLQEF-PVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTI 147
Query: 293 QLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAP 351
+ I+ + P L TLSL + + L+G T L LTL+ + L
Sbjct: 148 HFYDNPIQFVGRSAFQYLPKLHTLSL-NGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPS 206
Query: 352 ELFADLRALETFVMDGNELQ 371
+ L L + N+++
Sbjct: 207 GMCQQLPRLRVLELSHNQIE 226
>AF190501-1|AAG17168.1| 828|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 828
Score = 67.7 bits (158), Expect = 7e-11
Identities = 73/283 (25%), Positives = 121/283 (42%), Gaps = 32/283 (11%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N ++ + AF GL ++M +P + L LP L LN + +
Sbjct: 57 NHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLDLNYNK-LQEFPVAIR 115
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAF------------- 211
L+ L + I +P+ AF+G +L+ ++ ++N I + AF
Sbjct: 116 TLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNG 175
Query: 212 ----------RGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG 261
+G ++ +L+L + I+ LP+G+ PRL L + N L S
Sbjct: 176 AMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPS--LHR 233
Query: 262 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARN 320
++EI + +N + FS L +L+ L L ++IR + PE F + L L L N
Sbjct: 234 CQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDN 293
Query: 321 QLRVLPRSVLRGQTQLTSLTLSYN-AVAE-LAPELFADLRALE 361
QL LP + L G L L L N A+++ + + F LR LE
Sbjct: 294 QLTTLPLAGLGG---LMHLKLKGNLALSQAFSKDSFPKLRILE 333
Score = 66.1 bits (154), Expect = 2e-10
Identities = 53/200 (26%), Positives = 88/200 (44%), Gaps = 3/200 (1%)
Query: 173 ELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
+LS +T L F L LE+L + N +++I AF GL+++ +L L N++ +PA
Sbjct: 29 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 88
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTL 292
P L +L + N + R L +QE+ NN + E F P L+T+
Sbjct: 89 EALWELPSLQSLDLNYNKLQEF-PVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTI 147
Query: 293 QLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAP 351
+ I+ + P L TLSL + + L+G T L LTL+ + L
Sbjct: 148 HFYDNPIQFVGRSAFQYLPKLHTLSL-NGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPS 206
Query: 352 ELFADLRALETFVMDGNELQ 371
+ L L + N+++
Sbjct: 207 GMCQQLPRLRVLELSHNQIE 226
>BC016048-1|AAH16048.1| 317|Homo sapiens LRRC38 protein protein.
Length = 317
Score = 67.3 bits (157), Expect = 9e-11
Identities = 37/127 (29%), Positives = 69/127 (54%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
++ L ++ +I +P+D F+ L L+ N + ++ G F G + L L+ N +
Sbjct: 81 VRKLLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNLT 140
Query: 229 ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPA 288
L AG F S RL+ L++ N+ + + F L+ +Q +++++N +L A + LPA
Sbjct: 141 QLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLSVAALAALPA 200
Query: 289 LRTLQLD 295
LR+L+LD
Sbjct: 201 LRSLRLD 207
Score = 50.0 bits (114), Expect = 1e-05
Identities = 33/129 (25%), Positives = 64/129 (49%), Gaps = 1/129 (0%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
+ +L V N I I F ++ L N +++L G F+ + +L+ L + N+
Sbjct: 81 VRKLLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNLT 140
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP- 311
L + FR + ++ ++NN + + E F L +L+ L+L+ +++R L ++ P
Sbjct: 141 QLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLSVAALAALPA 200
Query: 312 LRTLSLARN 320
LR+L L N
Sbjct: 201 LRSLRLDGN 209
Score = 42.7 bits (96), Expect = 0.002
Identities = 39/130 (30%), Positives = 56/130 (43%), Gaps = 1/130 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
+V L + NRIQ +P F L+ L NS R L+ TF G + + +S N
Sbjct: 80 DVRKLLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNL 139
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
L F + L L L +++ + E+ F + L+ L L N LR L + L
Sbjct: 140 TQLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLSVAALAALP 199
Query: 335 QLTSLTLSYN 344
L SL L N
Sbjct: 200 ALRSLRLDGN 209
Score = 42.3 bits (95), Expect = 0.003
Identities = 39/173 (22%), Positives = 73/173 (42%), Gaps = 4/173 (2%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
L YL+ + + L + F G L L++ N + + AGAFR + LSL N +
Sbjct: 105 LVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNLTQLGAGAFRSAGRLVKLSLANNNLV 164
Query: 229 ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPA 288
+ F + L L + N+ R L L ++ +++ N L + F++L
Sbjct: 165 GVHEDAFETLESLQVLELNDNNLRSLSVAALAALPALRSLRLDGNP--WLCDCDFAHL-- 220
Query: 289 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTL 341
+Q + S + + +E + P+ + ++ +L S R LT L +
Sbjct: 221 FSWIQENASKLPKGLDEIQCSLPMESRRISLRELSEASFSECRFSLSLTDLCI 273
>AL603749-2|CAH70436.1| 294|Homo sapiens leucine rich repeat
containing 38 protein.
Length = 294
Score = 67.3 bits (157), Expect = 9e-11
Identities = 37/127 (29%), Positives = 69/127 (54%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
++ L ++ +I +P+D F+ L L+ N + ++ G F G + L L+ N +
Sbjct: 58 VRKLLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNLT 117
Query: 229 ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPA 288
L AG F S RL+ L++ N+ + + F L+ +Q +++++N +L A + LPA
Sbjct: 118 QLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLSVAALAALPA 177
Query: 289 LRTLQLD 295
LR+L+LD
Sbjct: 178 LRSLRLD 184
Score = 50.0 bits (114), Expect = 1e-05
Identities = 33/129 (25%), Positives = 64/129 (49%), Gaps = 1/129 (0%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
+ +L V N I I F ++ L N +++L G F+ + +L+ L + N+
Sbjct: 58 VRKLLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNLT 117
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP- 311
L + FR + ++ ++NN + + E F L +L+ L+L+ +++R L ++ P
Sbjct: 118 QLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLSVAALAALPA 177
Query: 312 LRTLSLARN 320
LR+L L N
Sbjct: 178 LRSLRLDGN 186
Score = 42.7 bits (96), Expect = 0.002
Identities = 39/130 (30%), Positives = 56/130 (43%), Gaps = 1/130 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
+V L + NRIQ +P F L+ L NS R L+ TF G + + +S N
Sbjct: 57 DVRKLLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNL 116
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
L F + L L L +++ + E+ F + L+ L L N LR L + L
Sbjct: 117 TQLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLSVAALAALP 176
Query: 335 QLTSLTLSYN 344
L SL L N
Sbjct: 177 ALRSLRLDGN 186
Score = 42.3 bits (95), Expect = 0.003
Identities = 39/173 (22%), Positives = 73/173 (42%), Gaps = 4/173 (2%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
L YL+ + + L + F G L L++ N + + AGAFR + LSL N +
Sbjct: 82 LVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNLTQLGAGAFRSAGRLVKLSLANNNLV 141
Query: 229 ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPA 288
+ F + L L + N+ R L L ++ +++ N L + F++L
Sbjct: 142 GVHEDAFETLESLQVLELNDNNLRSLSVAALAALPALRSLRLDGNP--WLCDCDFAHL-- 197
Query: 289 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTL 341
+Q + S + + +E + P+ + ++ +L S R LT L +
Sbjct: 198 FSWIQENASKLPKGLDEIQCSLPMESRRISLRELSEASFSECRFSLSLTDLCI 250
>AL354712-1|CAI21926.1| 294|Homo sapiens leucine rich repeat
containing 38 protein.
Length = 294
Score = 67.3 bits (157), Expect = 9e-11
Identities = 37/127 (29%), Positives = 69/127 (54%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
++ L ++ +I +P+D F+ L L+ N + ++ G F G + L L+ N +
Sbjct: 58 VRKLLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNLT 117
Query: 229 ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPA 288
L AG F S RL+ L++ N+ + + F L+ +Q +++++N +L A + LPA
Sbjct: 118 QLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLSVAALAALPA 177
Query: 289 LRTLQLD 295
LR+L+LD
Sbjct: 178 LRSLRLD 184
Score = 50.0 bits (114), Expect = 1e-05
Identities = 33/129 (25%), Positives = 64/129 (49%), Gaps = 1/129 (0%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
+ +L V N I I F ++ L N +++L G F+ + +L+ L + N+
Sbjct: 58 VRKLLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNLT 117
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP- 311
L + FR + ++ ++NN + + E F L +L+ L+L+ +++R L ++ P
Sbjct: 118 QLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLSVAALAALPA 177
Query: 312 LRTLSLARN 320
LR+L L N
Sbjct: 178 LRSLRLDGN 186
Score = 42.7 bits (96), Expect = 0.002
Identities = 39/130 (30%), Positives = 56/130 (43%), Gaps = 1/130 (0%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
+V L + NRIQ +P F L+ L NS R L+ TF G + + +S N
Sbjct: 57 DVRKLLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNL 116
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQT 334
L F + L L L +++ + E+ F + L+ L L N LR L + L
Sbjct: 117 TQLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLSVAALAALP 176
Query: 335 QLTSLTLSYN 344
L SL L N
Sbjct: 177 ALRSLRLDGN 186
Score = 42.3 bits (95), Expect = 0.003
Identities = 39/173 (22%), Positives = 73/173 (42%), Gaps = 4/173 (2%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
L YL+ + + L + F G L L++ N + + AGAFR + LSL N +
Sbjct: 82 LVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNLTQLGAGAFRSAGRLVKLSLANNNLV 141
Query: 229 ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPA 288
+ F + L L + N+ R L L ++ +++ N L + F++L
Sbjct: 142 GVHEDAFETLESLQVLELNDNNLRSLSVAALAALPALRSLRLDGNP--WLCDCDFAHL-- 197
Query: 289 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTL 341
+Q + S + + +E + P+ + ++ +L S R LT L +
Sbjct: 198 FSWIQENASKLPKGLDEIQCSLPMESRRISLRELSEASFSECRFSLSLTDLCI 250
>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
Length = 1496
Score = 66.9 bits (156), Expect = 1e-10
Identities = 41/123 (33%), Positives = 61/123 (49%), Gaps = 1/123 (0%)
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
N I I GAFR L N+ L LN N+I+ +P+G F L L + +N + +D + F+
Sbjct: 89 NRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFK 148
Query: 261 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLAR 319
GL ++++ + N TL F +LP L L L + I L P F ++ L L
Sbjct: 149 GLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDS 208
Query: 320 NQL 322
N L
Sbjct: 209 NTL 211
Score = 62.5 bits (145), Expect = 3e-09
Identities = 40/136 (29%), Positives = 66/136 (48%)
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
A P L+L +I + AF L L L + N+I I +GAF L N+ L L
Sbjct: 76 AVAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLY 135
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
KN IQ++ F L L + N LD ++F+ L ++ + + NN L F
Sbjct: 136 KNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTF 195
Query: 284 SNLPALRTLQLDLSSI 299
++L +++ L+LD +++
Sbjct: 196 NHLESMKRLRLDSNTL 211
Score = 58.0 bits (134), Expect = 5e-08
Identities = 37/131 (28%), Positives = 65/131 (49%)
Query: 143 PKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENE 202
P+ + L R + F L L L++ +I +P AF L L+ L +++NE
Sbjct: 79 PQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNE 138
Query: 203 IANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGL 262
I +I AF+GL ++ L L+ N+I+ L F P+L L + N +L TF L
Sbjct: 139 IQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHL 198
Query: 263 DHIQEIKISNN 273
+ ++ +++ +N
Sbjct: 199 ESMKRLRLDSN 209
Score = 45.6 bits (103), Expect = 3e-04
Identities = 34/136 (25%), Positives = 58/136 (42%), Gaps = 1/136 (0%)
Query: 236 ASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD 295
A P+ L + N R + FR L ++ + ++NN + F +L L+ L L
Sbjct: 76 AVAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLY 135
Query: 296 LSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELF 354
+ I+ + + F + L L L NQ+ L + +L L L N + L P F
Sbjct: 136 KNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTF 195
Query: 355 ADLRALETFVMDGNEL 370
L +++ +D N L
Sbjct: 196 NHLESMKRLRLDSNTL 211
Score = 45.6 bits (103), Expect = 3e-04
Identities = 39/134 (29%), Positives = 58/134 (43%), Gaps = 1/134 (0%)
Query: 140 RSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
R L L LN + + + F + LKYL L +I + AF GL LEQL +
Sbjct: 100 RRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLH 159
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
N+I + +F+ L + L L+ NRI L G F + L + N+ + D E
Sbjct: 160 FNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSNTL-HCDCEIL 218
Query: 260 RGLDHIQEIKISNN 273
D ++ S N
Sbjct: 219 WLADLLKTYAESGN 232
Score = 45.2 bits (102), Expect = 4e-04
Identities = 38/153 (24%), Positives = 63/153 (41%), Gaps = 4/153 (2%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
++L L NRI+ + G F L L + N + + S F L++++ + + N +
Sbjct: 82 SILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQS 141
Query: 278 LKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
+ F L +L L L + I L P+ F L L L N++ L +
Sbjct: 142 IDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESM 201
Query: 337 TSLTLSYNAV-AELAPELFADLRALETFVMDGN 368
L L N + + ADL L+T+ GN
Sbjct: 202 KRLRLDSNTLHCDCEILWLADL--LKTYAESGN 232
Score = 41.5 bits (93), Expect = 0.005
Identities = 30/123 (24%), Positives = 49/123 (39%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I + AF+ L ++ N +P L L + L ++ F
Sbjct: 89 NRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFK 148
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L L +I L D+F L LE+L + N I ++ G F L ++ L L+
Sbjct: 149 GLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDS 208
Query: 225 NRI 227
N +
Sbjct: 209 NTL 211
Score = 33.1 bits (72), Expect = 1.8
Identities = 21/73 (28%), Positives = 32/73 (43%)
Query: 102 VFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHAN 161
++KN I ++ AFKGL + + T+ D + LPKL L+ R L
Sbjct: 134 LYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPG 193
Query: 162 MFANTPPLKYLEL 174
F + +K L L
Sbjct: 194 TFNHLESMKRLRL 206
>BC126464-1|AAI26465.1| 1371|Homo sapiens erbb2 interacting protein
protein.
Length = 1371
Score = 66.9 bits (156), Expect = 1e-10
Identities = 59/199 (29%), Positives = 94/199 (47%), Gaps = 6/199 (3%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L+ S + +P + F LE+L + N+I + F ++ LSL N + LP
Sbjct: 27 LDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFN-CQSLHKLSLPDNDLTTLP 85
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRT 291
A + A+ L L + +N + E + + ++ S N P++ FS L L
Sbjct: 86 ASI-ANLINLRELDVSKNGIQEFP-ENIKNCKVLTIVEASVN-PISKLPDGFSQLLNLTQ 142
Query: 292 LQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAP 351
L L+ + + LP F + L+ L L NQL++LP+++ R TQL L L N E+ P
Sbjct: 143 LYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNR-LTQLERLDLGSNEFTEV-P 200
Query: 352 ELFADLRALETFVMDGNEL 370
E+ L L+ F MD N L
Sbjct: 201 EVLEQLSGLKEFWMDANRL 219
Score = 58.0 bits (134), Expect = 5e-08
Identities = 66/239 (27%), Positives = 103/239 (43%), Gaps = 17/239 (7%)
Query: 139 LRSLPKLTHFRLNAGRNITLHANMFANTPP-------LKYLELSDAKITVLPDDAFLG-L 190
L+ LPK T RL + L +N F P LK + ++T +P F+G L
Sbjct: 173 LKMLPK-TMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIP--GFIGSL 229
Query: 191 NVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNS 250
L L+V +N I + G N+ L L+ N +Q LP + + L + N
Sbjct: 230 KQLTYLDVSKNNIEMVEEG-ISTCENLQDLLLSSNSLQQLPETI-GLLKNITTLKIDENQ 287
Query: 251 FRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNS 310
YL ++ GL ++E+ S N L ++ L LRT D + +++LP E S
Sbjct: 288 LMYLP-DSIGGLISVEELDCSFNEVEALPSSI-GQLTNLRTFAADHNYLQQLPPEIGSWK 345
Query: 311 PLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNE 369
+ L L N+L LP + +L + LS N + L P F L+ L + N+
Sbjct: 346 NITVLFLHSNKLETLPEE-MGDMQKLKVINLSDNRLKNL-PFSFTKLQQLTAMWLSDNQ 402
Score = 53.6 bits (123), Expect = 1e-06
Identities = 61/210 (29%), Positives = 90/210 (42%), Gaps = 9/210 (4%)
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
F+ L L L+DA + LP + F L L+ L + EN++ + R L + L L
Sbjct: 134 FSQLLNLTQLYLNDAFLEFLPAN-FGRLTKLQILELRENQLKMLPKTMNR-LTQLERLDL 191
Query: 223 NKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG-LDHIQEIKISNNVPLTLKEA 281
N +P L L M N ++ F G L + + +S N ++E
Sbjct: 192 GSNEFTEVPEVL-EQLSGLKEFWMDANRLTFIPG--FIGSLKQLTYLDVSKNNIEMVEEG 248
Query: 282 VFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTL 341
+ S L+ L L +S+++LPE + TL + NQL LP S+ G + L
Sbjct: 249 I-STCENLQDLLLSSNSLQQLPETIGLLKNITTLKIDENQLMYLPDSI-GGLISVEELDC 306
Query: 342 SYNAVAELAPELFADLRALETFVMDGNELQ 371
S+N V E P L L TF D N LQ
Sbjct: 307 SFNEV-EALPSSIGQLTNLRTFAADHNYLQ 335
Score = 31.1 bits (67), Expect = 7.1
Identities = 14/51 (27%), Positives = 32/51 (62%), Gaps = 1/51 (1%)
Query: 322 LRVLPRSVLRGQTQ-LTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
+R++P LRG+ + +T+L S+ ++ ++ E+F + LE +D N+++
Sbjct: 9 VRLVPCRCLRGEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIE 59
>BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein.
Length = 722
Score = 66.9 bits (156), Expect = 1e-10
Identities = 41/123 (33%), Positives = 61/123 (49%), Gaps = 1/123 (0%)
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
N I I GAFR L N+ L LN N+I+ +P+G F L L + +N + +D + F+
Sbjct: 67 NRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFK 126
Query: 261 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLAR 319
GL ++++ + N TL F +LP L L L + I L P F ++ L L
Sbjct: 127 GLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDS 186
Query: 320 NQL 322
N L
Sbjct: 187 NTL 189
Score = 62.5 bits (145), Expect = 3e-09
Identities = 40/136 (29%), Positives = 66/136 (48%)
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
A P L+L +I + AF L L L + N+I I +GAF L N+ L L
Sbjct: 54 AVAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLY 113
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
KN IQ++ F L L + N LD ++F+ L ++ + + NN L F
Sbjct: 114 KNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTF 173
Query: 284 SNLPALRTLQLDLSSI 299
++L +++ L+LD +++
Sbjct: 174 NHLESMKRLRLDSNTL 189
Score = 58.0 bits (134), Expect = 5e-08
Identities = 37/131 (28%), Positives = 65/131 (49%)
Query: 143 PKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENE 202
P+ + L R + F L L L++ +I +P AF L L+ L +++NE
Sbjct: 57 PQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNE 116
Query: 203 IANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGL 262
I +I AF+GL ++ L L+ N+I+ L F P+L L + N +L TF L
Sbjct: 117 IQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHL 176
Query: 263 DHIQEIKISNN 273
+ ++ +++ +N
Sbjct: 177 ESMKRLRLDSN 187
Score = 45.6 bits (103), Expect = 3e-04
Identities = 34/136 (25%), Positives = 58/136 (42%), Gaps = 1/136 (0%)
Query: 236 ASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD 295
A P+ L + N R + FR L ++ + ++NN + F +L L+ L L
Sbjct: 54 AVAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLY 113
Query: 296 LSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELF 354
+ I+ + + F + L L L NQ+ L + +L L L N + L P F
Sbjct: 114 KNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTF 173
Query: 355 ADLRALETFVMDGNEL 370
L +++ +D N L
Sbjct: 174 NHLESMKRLRLDSNTL 189
Score = 45.6 bits (103), Expect = 3e-04
Identities = 39/134 (29%), Positives = 58/134 (43%), Gaps = 1/134 (0%)
Query: 140 RSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
R L L LN + + + F + LKYL L +I + AF GL LEQL +
Sbjct: 78 RRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLH 137
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
N+I + +F+ L + L L+ NRI L G F + L + N+ + D E
Sbjct: 138 FNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSNTL-HCDCEIL 196
Query: 260 RGLDHIQEIKISNN 273
D ++ S N
Sbjct: 197 WLADLLKTYAESGN 210
Score = 45.2 bits (102), Expect = 4e-04
Identities = 38/153 (24%), Positives = 63/153 (41%), Gaps = 4/153 (2%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
++L L NRI+ + G F L L + N + + S F L++++ + + N +
Sbjct: 60 SILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQS 119
Query: 278 LKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
+ F L +L L L + I L P+ F L L L N++ L +
Sbjct: 120 IDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESM 179
Query: 337 TSLTLSYNAV-AELAPELFADLRALETFVMDGN 368
L L N + + ADL L+T+ GN
Sbjct: 180 KRLRLDSNTLHCDCEILWLADL--LKTYAESGN 210
Score = 41.5 bits (93), Expect = 0.005
Identities = 30/123 (24%), Positives = 49/123 (39%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I + AF+ L ++ N +P L L + L ++ F
Sbjct: 67 NRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFK 126
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L L +I L D+F L LE+L + N I ++ G F L ++ L L+
Sbjct: 127 GLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDS 186
Query: 225 NRI 227
N +
Sbjct: 187 NTL 189
Score = 33.1 bits (72), Expect = 1.8
Identities = 21/73 (28%), Positives = 32/73 (43%)
Query: 102 VFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHAN 161
++KN I ++ AFKGL + + T+ D + LPKL L+ R L
Sbjct: 112 LYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPG 171
Query: 162 MFANTPPLKYLEL 174
F + +K L L
Sbjct: 172 TFNHLESMKRLRL 184
>AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated
antigen MG50 protein.
Length = 1496
Score = 66.9 bits (156), Expect = 1e-10
Identities = 41/123 (33%), Positives = 61/123 (49%), Gaps = 1/123 (0%)
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
N I I GAFR L N+ L LN N+I+ +P+G F L L + +N + +D + F+
Sbjct: 89 NRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFK 148
Query: 261 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLAR 319
GL ++++ + N TL F +LP L L L + I L P F ++ L L
Sbjct: 149 GLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDS 208
Query: 320 NQL 322
N L
Sbjct: 209 NTL 211
Score = 62.5 bits (145), Expect = 3e-09
Identities = 40/136 (29%), Positives = 66/136 (48%)
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLN 223
A P L+L +I + AF L L L + N+I I +GAF L N+ L L
Sbjct: 76 AVAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLY 135
Query: 224 KNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVF 283
KN IQ++ F L L + N LD ++F+ L ++ + + NN L F
Sbjct: 136 KNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTF 195
Query: 284 SNLPALRTLQLDLSSI 299
++L +++ L+LD +++
Sbjct: 196 NHLESMKRLRLDSNTL 211
Score = 58.0 bits (134), Expect = 5e-08
Identities = 37/131 (28%), Positives = 65/131 (49%)
Query: 143 PKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENE 202
P+ + L R + F L L L++ +I +P AF L L+ L +++NE
Sbjct: 79 PQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNE 138
Query: 203 IANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGL 262
I +I AF+GL ++ L L+ N+I+ L F P+L L + N +L TF L
Sbjct: 139 IQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHL 198
Query: 263 DHIQEIKISNN 273
+ ++ +++ +N
Sbjct: 199 ESMKRLRLDSN 209
Score = 45.6 bits (103), Expect = 3e-04
Identities = 34/136 (25%), Positives = 58/136 (42%), Gaps = 1/136 (0%)
Query: 236 ASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD 295
A P+ L + N R + FR L ++ + ++NN + F +L L+ L L
Sbjct: 76 AVAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLY 135
Query: 296 LSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELF 354
+ I+ + + F + L L L NQ+ L + +L L L N + L P F
Sbjct: 136 KNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTF 195
Query: 355 ADLRALETFVMDGNEL 370
L +++ +D N L
Sbjct: 196 NHLESMKRLRLDSNTL 211
Score = 45.6 bits (103), Expect = 3e-04
Identities = 39/134 (29%), Positives = 58/134 (43%), Gaps = 1/134 (0%)
Query: 140 RSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVW 199
R L L LN + + + F + LKYL L +I + AF GL LEQL +
Sbjct: 100 RRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLH 159
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
N+I + +F+ L + L L+ NRI L G F + L + N+ + D E
Sbjct: 160 FNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSNTL-HCDCEIL 218
Query: 260 RGLDHIQEIKISNN 273
D ++ S N
Sbjct: 219 WLADLLKTYAESGN 232
Score = 45.2 bits (102), Expect = 4e-04
Identities = 38/153 (24%), Positives = 63/153 (41%), Gaps = 4/153 (2%)
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
++L L NRI+ + G F L L + N + + S F L++++ + + N +
Sbjct: 82 SILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQS 141
Query: 278 LKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
+ F L +L L L + I L P+ F L L L N++ L +
Sbjct: 142 IDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESM 201
Query: 337 TSLTLSYNAV-AELAPELFADLRALETFVMDGN 368
L L N + + ADL L+T+ GN
Sbjct: 202 KRLRLDSNTLHCDCEILWLADL--LKTYAESGN 232
Score = 41.5 bits (93), Expect = 0.005
Identities = 30/123 (24%), Positives = 49/123 (39%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N I + AF+ L ++ N +P L L + L ++ F
Sbjct: 89 NRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFK 148
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNK 224
L+ L L +I L D+F L LE+L + N I ++ G F L ++ L L+
Sbjct: 149 GLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDS 208
Query: 225 NRI 227
N +
Sbjct: 209 NTL 211
Score = 33.1 bits (72), Expect = 1.8
Identities = 21/73 (28%), Positives = 32/73 (43%)
Query: 102 VFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHAN 161
++KN I ++ AFKGL + + T+ D + LPKL L+ R L
Sbjct: 134 LYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPG 193
Query: 162 MFANTPPLKYLEL 174
F + +K L L
Sbjct: 194 TFNHLESMKRLRL 206
>M14219-1|AAB00774.1| 359|Homo sapiens proteoglycan core protein
protein.
Length = 359
Score = 66.5 bits (155), Expect = 2e-10
Identities = 54/207 (26%), Positives = 97/207 (46%), Gaps = 9/207 (4%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P L+L + KIT + D F L L L + N+I+ ++ GAF L + L L+KN+
Sbjct: 81 PDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQ 140
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT---LKEAVF 283
++ LP + L L N + TF GL+ + I++ N PL ++ F
Sbjct: 141 LKELPEKM---PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTN-PLKSSGIENGAF 196
Query: 284 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+ L +++ ++I +P+ + L L L N++ + + L+G L L LS+
Sbjct: 197 QGMKKLSYIRIADTNITSIPQGLPPS--LTELHLDGNKISRVDAASLKGLNNLAKLGLSF 254
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
N+++ + A+ L +D N+L
Sbjct: 255 NSISAVDNGSLANTPHLRELHLDNNKL 281
Score = 59.7 bits (138), Expect = 2e-08
Identities = 54/227 (23%), Positives = 99/227 (43%), Gaps = 10/227 (4%)
Query: 105 NAINPLNADAFKGL-GITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N I + FK L + AL++ N P L KL L+ + L M
Sbjct: 91 NKITEIKDGDFKNLKNLHALILVNNKISKVSP-GAFTPLVKLERLYLSKNQLKELPEKM- 148
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEI--ANITAGAFRGLHNVTVLS 221
L+ L + +IT + F GLN + + + N + + I GAF+G+ ++ +
Sbjct: 149 --PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEA 281
+ I ++P GL P L L + N +D+ + +GL+++ ++ +S N +
Sbjct: 207 IADTNITSIPQGL---PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG 263
Query: 282 VFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRS 328
+N P LR L LD + + +P + ++ + L N + V+ S
Sbjct: 264 SLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSS 310
>CR541946-1|CAG46744.1| 359|Homo sapiens DCN protein.
Length = 359
Score = 66.5 bits (155), Expect = 2e-10
Identities = 54/207 (26%), Positives = 97/207 (46%), Gaps = 9/207 (4%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P L+L + KIT + D F L L L + N+I+ ++ GAF L + L L+KN+
Sbjct: 81 PDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQ 140
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT---LKEAVF 283
++ LP + L L N + TF GL+ + I++ N PL ++ F
Sbjct: 141 LKELPEKM---PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTN-PLKSSGIENGAF 196
Query: 284 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+ L +++ ++I +P+ + L L L N++ + + L+G L L LS+
Sbjct: 197 QGMKKLSYIRIADTNITSIPQGLPPS--LTELHLDGNKISRVDAASLKGLNNLAKLGLSF 254
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
N+++ + A+ L +D N+L
Sbjct: 255 NSISAVDNGSLANTPHLRELHLDNNKL 281
Score = 59.7 bits (138), Expect = 2e-08
Identities = 54/227 (23%), Positives = 99/227 (43%), Gaps = 10/227 (4%)
Query: 105 NAINPLNADAFKGL-GITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N I + FK L + AL++ N P L KL L+ + L M
Sbjct: 91 NKITEIKDGDFKNLKNLHALILVNNKISKVSP-GAFTPLVKLERLYLSKNQLKELPEKM- 148
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEI--ANITAGAFRGLHNVTVLS 221
L+ L + +IT + F GLN + + + N + + I GAF+G+ ++ +
Sbjct: 149 --PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEA 281
+ I ++P GL P L L + N +D+ + +GL+++ ++ +S N +
Sbjct: 207 IADTNITSIPQGL---PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG 263
Query: 282 VFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRS 328
+N P LR L LD + + +P + ++ + L N + V+ S
Sbjct: 264 SLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSS 310
>CR407676-1|CAG28604.1| 359|Homo sapiens DCN protein.
Length = 359
Score = 66.5 bits (155), Expect = 2e-10
Identities = 54/207 (26%), Positives = 97/207 (46%), Gaps = 9/207 (4%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P L+L + KIT + D F L L L + N+I+ ++ GAF L + L L+KN+
Sbjct: 81 PDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQ 140
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT---LKEAVF 283
++ LP + L L N + TF GL+ + I++ N PL ++ F
Sbjct: 141 LKELPEKM---PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTN-PLKSSGIENGAF 196
Query: 284 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+ L +++ ++I +P+ + L L L N++ + + L+G L L LS+
Sbjct: 197 QGMKKLSYIRIADTNITSIPQGLPPS--LTELHLDGNKISRVDAASLKGLNNLAKLGLSF 254
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
N+++ + A+ L +D N+L
Sbjct: 255 NSISAVDNGSLANTPHLRELHLDNNKL 281
Score = 59.7 bits (138), Expect = 2e-08
Identities = 54/227 (23%), Positives = 99/227 (43%), Gaps = 10/227 (4%)
Query: 105 NAINPLNADAFKGL-GITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N I + FK L + AL++ N P L KL L+ + L M
Sbjct: 91 NKITEIKDGDFKNLKNLHALILVNNKISKVSP-GAFTPLVKLERLYLSKNQLKELPEKM- 148
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEI--ANITAGAFRGLHNVTVLS 221
L+ L + +IT + F GLN + + + N + + I GAF+G+ ++ +
Sbjct: 149 --PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEA 281
+ I ++P GL P L L + N +D+ + +GL+++ ++ +S N +
Sbjct: 207 IADTNITSIPQGL---PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG 263
Query: 282 VFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRS 328
+N P LR L LD + + +P + ++ + L N + V+ S
Sbjct: 264 SLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSS 310
>BT019800-1|AAV38603.1| 359|Homo sapiens decorin protein.
Length = 359
Score = 66.5 bits (155), Expect = 2e-10
Identities = 54/207 (26%), Positives = 97/207 (46%), Gaps = 9/207 (4%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P L+L + KIT + D F L L L + N+I+ ++ GAF L + L L+KN+
Sbjct: 81 PDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQ 140
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT---LKEAVF 283
++ LP + L L N + TF GL+ + I++ N PL ++ F
Sbjct: 141 LKELPEKM---PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTN-PLKSSGIENGAF 196
Query: 284 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+ L +++ ++I +P+ + L L L N++ + + L+G L L LS+
Sbjct: 197 QGMKKLSYIRIADTNITSIPQGLPPS--LTELHLDGNKISRVDAASLKGLNNLAKLGLSF 254
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
N+++ + A+ L +D N+L
Sbjct: 255 NSISAVDNGSLANTPHLRELHLDNNKL 281
Score = 59.7 bits (138), Expect = 2e-08
Identities = 54/227 (23%), Positives = 99/227 (43%), Gaps = 10/227 (4%)
Query: 105 NAINPLNADAFKGL-GITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N I + FK L + AL++ N P L KL L+ + L M
Sbjct: 91 NKITEIKDGDFKNLKNLHALILVNNKISKVSP-GAFTPLVKLERLYLSKNQLKELPEKM- 148
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEI--ANITAGAFRGLHNVTVLS 221
L+ L + +IT + F GLN + + + N + + I GAF+G+ ++ +
Sbjct: 149 --PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEA 281
+ I ++P GL P L L + N +D+ + +GL+++ ++ +S N +
Sbjct: 207 IADTNITSIPQGL---PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG 263
Query: 282 VFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRS 328
+N P LR L LD + + +P + ++ + L N + V+ S
Sbjct: 264 SLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSS 310
>BC128608-1|AAI28609.1| 441|Homo sapiens reticulon 4 receptor-like
1 protein.
Length = 441
Score = 66.5 bits (155), Expect = 2e-10
Identities = 51/167 (30%), Positives = 80/167 (47%), Gaps = 4/167 (2%)
Query: 155 NIT-LHANMFANTPPLKYLELSDAK-ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR 212
NIT +H + F L+ L+L D + + L + F GL L L +++ ++ + AG F
Sbjct: 87 NITYIHPSTFEGFVHLEELDLGDNRQLRTLAPETFQGLVKLHALYLYKCGLSALPAGVFG 146
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISN 272
GLH++ L L N I+ L +F L +L + N L TFRGL ++ + +
Sbjct: 147 GLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLFLHGNKLWSLGPGTFRGLVNLDRLLLHE 206
Query: 273 NVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLAR 319
N + F +L L TL L +S+ EL E + +PL L R
Sbjct: 207 NQLQWVHHKAFHDLRRLTTLFLFNNSLSELQGECL--APLGALEFLR 251
Score = 63.3 bits (147), Expect = 1e-09
Identities = 47/173 (27%), Positives = 80/173 (46%), Gaps = 1/173 (0%)
Query: 102 VFKNAINPLNADAFKG-LGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHA 160
++ N I ++ F+G + + L + + T+ + + L KL L L A
Sbjct: 83 IYSNNITYIHPSTFEGFVHLEELDLGDNRQLRTLAPETFQGLVKLHALYLYKCGLSALPA 142
Query: 161 NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVL 220
+F L+YL L D I L DD F+ L L L + N++ ++ G FRGL N+ L
Sbjct: 143 GVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLFLHGNKLWSLGPGTFRGLVNLDRL 202
Query: 221 SLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L++N++Q + F RL L + NS L E L ++ ++++ N
Sbjct: 203 LLHENQLQWVHHKAFHDLRRLTTLFLFNNSLSELQGECLAPLGALEFLRLNGN 255
Score = 57.6 bits (133), Expect = 7e-08
Identities = 45/152 (29%), Positives = 66/152 (43%), Gaps = 4/152 (2%)
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL-TLKE 280
L NRI L G F+ P ++ L + N+ Y+ TF G H++E+ + +N L TL
Sbjct: 61 LQNNRIGLLQPGHFS--PAMVTLWIYSNNITYIHPSTFEGFVHLEELDLGDNRQLRTLAP 118
Query: 281 AVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSL 339
F L L L L + LP F L+ L L N + L + L+ L
Sbjct: 119 ETFQGLVKLHALYLYKCGLSALPAGVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHL 178
Query: 340 TLSYNAVAELAPELFADLRALETFVMDGNELQ 371
L N + L P F L L+ ++ N+LQ
Sbjct: 179 FLHGNKLWSLGPGTFRGLVNLDRLLLHENQLQ 210
Score = 57.2 bits (132), Expect = 9e-08
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 2/178 (1%)
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNR-IQALPAGLFASTPRLLNLTMMRNSFRYLDS 256
++ N I I F G ++ L L NR ++ L F +L L + + L +
Sbjct: 83 IYSNNITYIHPSTFEGFVHLEELDLGDNRQLRTLAPETFQGLVKLHALYLYKCGLSALPA 142
Query: 257 ETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTL 315
F GL +Q + + +N L++ +F +L L L L + + L P F L L
Sbjct: 143 GVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLFLHGNKLWSLGPGTFRGLVNLDRL 202
Query: 316 SLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVG 373
L NQL+ + +LT+L L N+++EL E A L ALE ++GN G
Sbjct: 203 LLHENQLQWVHHKAFHDLRRLTTLFLFNNSLSELQGECLAPLGALEFLRLNGNPWDCG 260
Score = 49.2 bits (112), Expect = 3e-05
Identities = 37/139 (26%), Positives = 62/139 (44%)
Query: 157 TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHN 216
TL F L L L ++ LP F GL+ L+ L + +N I + F L N
Sbjct: 115 TLAPETFQGLVKLHALYLYKCGLSALPAGVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVN 174
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
++ L L+ N++ +L G F L L + N +++ + F L + + + NN
Sbjct: 175 LSHLFLHGNKLWSLGPGTFRGLVNLDRLLLHENQLQWVHHKAFHDLRRLTTLFLFNNSLS 234
Query: 277 TLKEAVFSNLPALRTLQLD 295
L+ + L AL L+L+
Sbjct: 235 ELQGECLAPLGALEFLRLN 253
>BC040986-1|AAH40986.1| 837|Homo sapiens SLIT and NTRK-like family,
member 4 protein.
Length = 837
Score = 66.5 bits (155), Expect = 2e-10
Identities = 42/152 (27%), Positives = 72/152 (47%), Gaps = 1/152 (0%)
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
++L+V N I ++ F + +L L N+I + +F + L L + N
Sbjct: 380 KKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIER 439
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLR 313
L E F GL ++Q + + N+ + F ++P L+ L L+ + ++ LP S +PL
Sbjct: 440 LYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAPLA 499
Query: 314 TLSLARNQLRVLPRSVLRGQTQ-LTSLTLSYN 344
L+L N+ LP S + Q Q LT + L N
Sbjct: 500 RLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 531
Score = 58.8 bits (136), Expect = 3e-08
Identities = 42/148 (28%), Positives = 68/148 (45%), Gaps = 2/148 (1%)
Query: 127 NAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDA 186
N + V V L L + + + ++F N L+ L L+ +I L +
Sbjct: 385 NGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEI 444
Query: 187 FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTM 246
F GL+ L+ L + N I I+AG F + N+ +L LN N +++LP +F+ P L L +
Sbjct: 445 FSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP-LARLNL 503
Query: 247 MRNSFRYLD-SETFRGLDHIQEIKISNN 273
N F YL S L + +I + N
Sbjct: 504 RNNKFMYLPVSGVLDQLQSLTQIDLEGN 531
Score = 55.6 bits (128), Expect = 3e-07
Identities = 41/134 (30%), Positives = 60/134 (44%), Gaps = 2/134 (1%)
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
F + L L L +ITV+ D F L L +L + N+I + F GLHN+ L L
Sbjct: 397 FTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYL 456
Query: 223 NKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLK-EA 281
N I+ + AG F S P L L + N + L F G + + + NN + L
Sbjct: 457 EYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP-LARLNLRNNKFMYLPVSG 515
Query: 282 VFSNLPALRTLQLD 295
V L +L + L+
Sbjct: 516 VLDQLQSLTQIDLE 529
Score = 54.4 bits (125), Expect = 7e-07
Identities = 36/120 (30%), Positives = 55/120 (45%), Gaps = 2/120 (1%)
Query: 143 PKLTHFRLNAGRNIT--LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
P + LN N L+ N F N L L + K+ + AFLGL+ L+QL++
Sbjct: 57 PWSNFYHLNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNN 116
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
NE+ + A F G+ N+ L + N I+ + G F +L L + N +L FR
Sbjct: 117 NELKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFR 176
Score = 54.0 bits (124), Expect = 9e-07
Identities = 31/131 (23%), Positives = 61/131 (46%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
LN N + + F + L L N++Q + G F L L + N + L
Sbjct: 64 LNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILR 123
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
++TF G+++++ ++ N+ ++ F+ L L+ L L+ + I LP+ + L L
Sbjct: 124 ADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFRFASLTHL 183
Query: 316 SLARNQLRVLP 326
+ N+++ LP
Sbjct: 184 DIRGNRIQKLP 194
Score = 52.4 bits (120), Expect = 3e-06
Identities = 34/133 (25%), Positives = 64/133 (48%), Gaps = 1/133 (0%)
Query: 171 YLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
+L + + +L + FL + L++ N++ NI GAF GL + L LN N ++ L
Sbjct: 63 HLNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKIL 122
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
A F L L N +Y++ F L ++ + +++N+ L + +F +L
Sbjct: 123 RADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIF-RFASLT 181
Query: 291 TLQLDLSSIRELP 303
L + + I++LP
Sbjct: 182 HLDIRGNRIQKLP 194
Score = 50.0 bits (114), Expect = 1e-05
Identities = 38/150 (25%), Positives = 67/150 (44%), Gaps = 1/150 (0%)
Query: 154 RNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRG 213
+NI + + K L ++ I + F L+ L++ N+I I F
Sbjct: 364 KNIQSMSELIPKPLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHN 423
Query: 214 LHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L N+ L LN N+I+ L +F+ L L + N + + + TF + ++Q + ++NN
Sbjct: 424 LTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNN 483
Query: 274 VPLTLKEAVFSNLPALRTLQLDLSSIRELP 303
+ +L +FS P R L L + LP
Sbjct: 484 LLKSLPVYIFSGAPLAR-LNLRNNKFMYLP 512
Score = 43.2 bits (97), Expect = 0.002
Identities = 40/155 (25%), Positives = 66/155 (42%), Gaps = 3/155 (1%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L +N N I+ + F L L + N + + F L +++ + ++ N
Sbjct: 378 NAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQI 437
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQT 334
L +FS L L+ L L+ + I+E+ + P L+ L L N L+ LP + G
Sbjct: 438 ERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSG-A 496
Query: 335 QLTSLTLSYNAVAELAPELFAD-LRALETFVMDGN 368
L L L N L D L++L ++GN
Sbjct: 497 PLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 531
Score = 38.7 bits (86), Expect = 0.035
Identities = 44/183 (24%), Positives = 78/183 (42%), Gaps = 6/183 (3%)
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQAL---PAGLFAST-PRLLNLTMMRNSFRYLD- 255
++I+ I AG N++ + + R+ L PA F T P L L++
Sbjct: 310 SKISGIVAGKALSNRNLSQIVSYQTRVPPLTPCPAPCFCKTHPSDLGLSVNCQEKNIQSM 369
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRT 314
SE + +++ ++ N + + F++ L L L + I + + N + LR
Sbjct: 370 SELIPKPLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRR 429
Query: 315 LSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVGY 374
L L NQ+ L + G L L L YN + E++ F + L+ ++ N L+
Sbjct: 430 LYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLP 489
Query: 375 VYI 377
VYI
Sbjct: 490 VYI 492
Score = 33.5 bits (73), Expect = 1.3
Identities = 24/102 (23%), Positives = 41/102 (40%), Gaps = 1/102 (0%)
Query: 268 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLP 326
+ NN L F N +L L + ++ + F+ S L+ L L N+L++L
Sbjct: 64 LNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILR 123
Query: 327 RSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
G L L YN + + F L L+ +++ N
Sbjct: 124 ADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDN 165
Score = 30.7 bits (66), Expect = 9.4
Identities = 28/122 (22%), Positives = 45/122 (36%), Gaps = 2/122 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + + AF GL + N + D + L + + + + F
Sbjct: 93 NKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLGIENLEYLQADYNLIKYIERGAFN 152
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANIT-AGAFRGLHNVTVLSLN 223
LK L L+D I+ LPD+ F + L L++ N I + G + V L L
Sbjct: 153 KLHKLKVLILNDNLISFLPDNIFRFAS-LTHLDIRGNRIQKLPYIGVLEHIGRVVELQLE 211
Query: 224 KN 225
N
Sbjct: 212 DN 213
>BC005322-1|AAH05322.1| 359|Homo sapiens decorin protein.
Length = 359
Score = 66.5 bits (155), Expect = 2e-10
Identities = 54/207 (26%), Positives = 97/207 (46%), Gaps = 9/207 (4%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P L+L + KIT + D F L L L + N+I+ ++ GAF L + L L+KN+
Sbjct: 81 PDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQ 140
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT---LKEAVF 283
++ LP + L L N + TF GL+ + I++ N PL ++ F
Sbjct: 141 LKELPEKM---PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTN-PLKSSGIENGAF 196
Query: 284 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+ L +++ ++I +P+ + L L L N++ + + L+G L L LS+
Sbjct: 197 QGMKKLSYIRIADTNITSIPQGLPPS--LTELHLDGNKISRVDAASLKGLNNLAKLGLSF 254
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
N+++ + A+ L +D N+L
Sbjct: 255 NSISAVDNGSLANTPHLRELHLDNNKL 281
Score = 59.7 bits (138), Expect = 2e-08
Identities = 54/227 (23%), Positives = 99/227 (43%), Gaps = 10/227 (4%)
Query: 105 NAINPLNADAFKGL-GITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N I + FK L + AL++ N P L KL L+ + L M
Sbjct: 91 NKITEIKDGDFKNLKNLHALILVNNKISKVSP-GAFTPLVKLERLYLSKNQLKELPEKM- 148
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEI--ANITAGAFRGLHNVTVLS 221
L+ L + +IT + F GLN + + + N + + I GAF+G+ ++ +
Sbjct: 149 --PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEA 281
+ I ++P GL P L L + N +D+ + +GL+++ ++ +S N +
Sbjct: 207 IADTNITSIPQGL---PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG 263
Query: 282 VFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRS 328
+N P LR L LD + + +P + ++ + L N + V+ S
Sbjct: 264 SLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSS 310
>AY250219-1|AAP82836.1| 441|Homo sapiens nogo receptor-like 2
protein.
Length = 441
Score = 66.5 bits (155), Expect = 2e-10
Identities = 51/167 (30%), Positives = 80/167 (47%), Gaps = 4/167 (2%)
Query: 155 NIT-LHANMFANTPPLKYLELSDAK-ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR 212
NIT +H + F L+ L+L D + + L + F GL L L +++ ++ + AG F
Sbjct: 87 NITYIHPSTFEGFVHLEELDLGDNRQLRTLAPETFQGLVKLHALYLYKCGLSALPAGVFG 146
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISN 272
GLH++ L L N I+ L +F L +L + N L TFRGL ++ + +
Sbjct: 147 GLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLFLHGNKLWSLGPGTFRGLVNLDRLLLHE 206
Query: 273 NVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLAR 319
N + F +L L TL L +S+ EL E + +PL L R
Sbjct: 207 NQLQWVHHKAFHDLRRLTTLFLFNNSLSELQGECL--APLGALEFLR 251
Score = 63.3 bits (147), Expect = 1e-09
Identities = 47/173 (27%), Positives = 80/173 (46%), Gaps = 1/173 (0%)
Query: 102 VFKNAINPLNADAFKG-LGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHA 160
++ N I ++ F+G + + L + + T+ + + L KL L L A
Sbjct: 83 IYSNNITYIHPSTFEGFVHLEELDLGDNRQLRTLAPETFQGLVKLHALYLYKCGLSALPA 142
Query: 161 NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVL 220
+F L+YL L D I L DD F+ L L L + N++ ++ G FRGL N+ L
Sbjct: 143 GVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLFLHGNKLWSLGPGTFRGLVNLDRL 202
Query: 221 SLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L++N++Q + F RL L + NS L E L ++ ++++ N
Sbjct: 203 LLHENQLQWVHHKAFHDLRRLTTLFLFNNSLSELQGECLAPLGALEFLRLNGN 255
Score = 57.6 bits (133), Expect = 7e-08
Identities = 45/152 (29%), Positives = 66/152 (43%), Gaps = 4/152 (2%)
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL-TLKE 280
L NRI L G F+ P ++ L + N+ Y+ TF G H++E+ + +N L TL
Sbjct: 61 LQNNRIGLLQPGHFS--PAMVTLWIYSNNITYIHPSTFEGFVHLEELDLGDNRQLRTLAP 118
Query: 281 AVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSL 339
F L L L L + LP F L+ L L N + L + L+ L
Sbjct: 119 ETFQGLVKLHALYLYKCGLSALPAGVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHL 178
Query: 340 TLSYNAVAELAPELFADLRALETFVMDGNELQ 371
L N + L P F L L+ ++ N+LQ
Sbjct: 179 FLHGNKLWSLGPGTFRGLVNLDRLLLHENQLQ 210
Score = 57.2 bits (132), Expect = 9e-08
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 2/178 (1%)
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNR-IQALPAGLFASTPRLLNLTMMRNSFRYLDS 256
++ N I I F G ++ L L NR ++ L F +L L + + L +
Sbjct: 83 IYSNNITYIHPSTFEGFVHLEELDLGDNRQLRTLAPETFQGLVKLHALYLYKCGLSALPA 142
Query: 257 ETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTL 315
F GL +Q + + +N L++ +F +L L L L + + L P F L L
Sbjct: 143 GVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLFLHGNKLWSLGPGTFRGLVNLDRL 202
Query: 316 SLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVG 373
L NQL+ + +LT+L L N+++EL E A L ALE ++GN G
Sbjct: 203 LLHENQLQWVHHKAFHDLRRLTTLFLFNNSLSELQGECLAPLGALEFLRLNGNPWDCG 260
Score = 49.2 bits (112), Expect = 3e-05
Identities = 37/139 (26%), Positives = 62/139 (44%)
Query: 157 TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHN 216
TL F L L L ++ LP F GL+ L+ L + +N I + F L N
Sbjct: 115 TLAPETFQGLVKLHALYLYKCGLSALPAGVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVN 174
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
++ L L+ N++ +L G F L L + N +++ + F L + + + NN
Sbjct: 175 LSHLFLHGNKLWSLGPGTFRGLVNLDRLLLHENQLQWVHHKAFHDLRRLTTLFLFNNSLS 234
Query: 277 TLKEAVFSNLPALRTLQLD 295
L+ + L AL L+L+
Sbjct: 235 ELQGECLAPLGALEFLRLN 253
>AL713693-1|CAD28493.1| 689|Homo sapiens hypothetical protein
protein.
Length = 689
Score = 66.5 bits (155), Expect = 2e-10
Identities = 42/152 (27%), Positives = 72/152 (47%), Gaps = 1/152 (0%)
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
++L+V N I ++ F + +L L N+I + +F + L L + N
Sbjct: 232 KKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIER 291
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLR 313
L E F GL ++Q + + N+ + F ++P L+ L L+ + ++ LP S +PL
Sbjct: 292 LYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAPLA 351
Query: 314 TLSLARNQLRVLPRSVLRGQTQ-LTSLTLSYN 344
L+L N+ LP S + Q Q LT + L N
Sbjct: 352 RLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 383
Score = 58.8 bits (136), Expect = 3e-08
Identities = 42/148 (28%), Positives = 68/148 (45%), Gaps = 2/148 (1%)
Query: 127 NAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDA 186
N + V V L L + + + ++F N L+ L L+ +I L +
Sbjct: 237 NGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEI 296
Query: 187 FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTM 246
F GL+ L+ L + N I I+AG F + N+ +L LN N +++LP +F+ P L L +
Sbjct: 297 FSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP-LARLNL 355
Query: 247 MRNSFRYLD-SETFRGLDHIQEIKISNN 273
N F YL S L + +I + N
Sbjct: 356 RNNKFMYLPVSGVLDQLQSLTQIDLEGN 383
Score = 55.6 bits (128), Expect = 3e-07
Identities = 41/134 (30%), Positives = 60/134 (44%), Gaps = 2/134 (1%)
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
F + L L L +ITV+ D F L L +L + N+I + F GLHN+ L L
Sbjct: 249 FTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYL 308
Query: 223 NKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLK-EA 281
N I+ + AG F S P L L + N + L F G + + + NN + L
Sbjct: 309 EYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP-LARLNLRNNKFMYLPVSG 367
Query: 282 VFSNLPALRTLQLD 295
V L +L + L+
Sbjct: 368 VLDQLQSLTQIDLE 381
Score = 50.0 bits (114), Expect = 1e-05
Identities = 38/150 (25%), Positives = 67/150 (44%), Gaps = 1/150 (0%)
Query: 154 RNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRG 213
+NI + + K L ++ I + F L+ L++ N+I I F
Sbjct: 216 KNIQSMSELIPKPLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHN 275
Query: 214 LHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L N+ L LN N+I+ L +F+ L L + N + + + TF + ++Q + ++NN
Sbjct: 276 LTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNN 335
Query: 274 VPLTLKEAVFSNLPALRTLQLDLSSIRELP 303
+ +L +FS P R L L + LP
Sbjct: 336 LLKSLPVYIFSGAPLAR-LNLRNNKFMYLP 364
Score = 43.2 bits (97), Expect = 0.002
Identities = 40/155 (25%), Positives = 66/155 (42%), Gaps = 3/155 (1%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L +N N I+ + F L L + N + + F L +++ + ++ N
Sbjct: 230 NAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQI 289
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQT 334
L +FS L L+ L L+ + I+E+ + P L+ L L N L+ LP + G
Sbjct: 290 ERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSG-A 348
Query: 335 QLTSLTLSYNAVAELAPELFAD-LRALETFVMDGN 368
L L L N L D L++L ++GN
Sbjct: 349 PLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 383
Score = 38.7 bits (86), Expect = 0.035
Identities = 44/183 (24%), Positives = 78/183 (42%), Gaps = 6/183 (3%)
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQAL---PAGLFAST-PRLLNLTMMRNSFRYLD- 255
++I+ I AG N++ + + R+ L PA F T P L L++
Sbjct: 162 SKISGIVAGKALSNRNLSQIVSYQTRVPPLTPCPAPCFCKTHPSDLGLSVNCQEKNIQSM 221
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRT 314
SE + +++ ++ N + + F++ L L L + I + + N + LR
Sbjct: 222 SELIPKPLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRR 281
Query: 315 LSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVGY 374
L L NQ+ L + G L L L YN + E++ F + L+ ++ N L+
Sbjct: 282 LYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLP 341
Query: 375 VYI 377
VYI
Sbjct: 342 VYI 344
>AL080239-3|CAI41650.1| 837|Homo sapiens novel protein protein.
Length = 837
Score = 66.5 bits (155), Expect = 2e-10
Identities = 42/152 (27%), Positives = 72/152 (47%), Gaps = 1/152 (0%)
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
++L+V N I ++ F + +L L N+I + +F + L L + N
Sbjct: 380 KKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIER 439
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLR 313
L E F GL ++Q + + N+ + F ++P L+ L L+ + ++ LP S +PL
Sbjct: 440 LYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAPLA 499
Query: 314 TLSLARNQLRVLPRSVLRGQTQ-LTSLTLSYN 344
L+L N+ LP S + Q Q LT + L N
Sbjct: 500 RLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 531
Score = 58.8 bits (136), Expect = 3e-08
Identities = 42/148 (28%), Positives = 68/148 (45%), Gaps = 2/148 (1%)
Query: 127 NAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDA 186
N + V V L L + + + ++F N L+ L L+ +I L +
Sbjct: 385 NGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEI 444
Query: 187 FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTM 246
F GL+ L+ L + N I I+AG F + N+ +L LN N +++LP +F+ P L L +
Sbjct: 445 FSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP-LARLNL 503
Query: 247 MRNSFRYLD-SETFRGLDHIQEIKISNN 273
N F YL S L + +I + N
Sbjct: 504 RNNKFMYLPVSGVLDQLQSLTQIDLEGN 531
Score = 55.6 bits (128), Expect = 3e-07
Identities = 41/134 (30%), Positives = 60/134 (44%), Gaps = 2/134 (1%)
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
F + L L L +ITV+ D F L L +L + N+I + F GLHN+ L L
Sbjct: 397 FTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYL 456
Query: 223 NKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLK-EA 281
N I+ + AG F S P L L + N + L F G + + + NN + L
Sbjct: 457 EYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP-LARLNLRNNKFMYLPVSG 515
Query: 282 VFSNLPALRTLQLD 295
V L +L + L+
Sbjct: 516 VLDQLQSLTQIDLE 529
Score = 54.4 bits (125), Expect = 7e-07
Identities = 36/120 (30%), Positives = 55/120 (45%), Gaps = 2/120 (1%)
Query: 143 PKLTHFRLNAGRNIT--LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
P + LN N L+ N F N L L + K+ + AFLGL+ L+QL++
Sbjct: 57 PWSNFYHLNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNN 116
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
NE+ + A F G+ N+ L + N I+ + G F +L L + N +L FR
Sbjct: 117 NELKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFR 176
Score = 54.0 bits (124), Expect = 9e-07
Identities = 31/131 (23%), Positives = 61/131 (46%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLD 255
LN N + + F + L L N++Q + G F L L + N + L
Sbjct: 64 LNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILR 123
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
++TF G+++++ ++ N+ ++ F+ L L+ L L+ + I LP+ + L L
Sbjct: 124 ADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFRFASLTHL 183
Query: 316 SLARNQLRVLP 326
+ N+++ LP
Sbjct: 184 DIRGNRIQKLP 194
Score = 52.4 bits (120), Expect = 3e-06
Identities = 34/133 (25%), Positives = 64/133 (48%), Gaps = 1/133 (0%)
Query: 171 YLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
+L + + +L + FL + L++ N++ NI GAF GL + L LN N ++ L
Sbjct: 63 HLNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKIL 122
Query: 231 PAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALR 290
A F L L N +Y++ F L ++ + +++N+ L + +F +L
Sbjct: 123 RADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIF-RFASLT 181
Query: 291 TLQLDLSSIRELP 303
L + + I++LP
Sbjct: 182 HLDIRGNRIQKLP 194
Score = 50.0 bits (114), Expect = 1e-05
Identities = 38/150 (25%), Positives = 67/150 (44%), Gaps = 1/150 (0%)
Query: 154 RNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRG 213
+NI + + K L ++ I + F L+ L++ N+I I F
Sbjct: 364 KNIQSMSELIPKPLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHN 423
Query: 214 LHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L N+ L LN N+I+ L +F+ L L + N + + + TF + ++Q + ++NN
Sbjct: 424 LTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNN 483
Query: 274 VPLTLKEAVFSNLPALRTLQLDLSSIRELP 303
+ +L +FS P R L L + LP
Sbjct: 484 LLKSLPVYIFSGAPLAR-LNLRNNKFMYLP 512
Score = 43.2 bits (97), Expect = 0.002
Identities = 40/155 (25%), Positives = 66/155 (42%), Gaps = 3/155 (1%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L +N N I+ + F L L + N + + F L +++ + ++ N
Sbjct: 378 NAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQI 437
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQT 334
L +FS L L+ L L+ + I+E+ + P L+ L L N L+ LP + G
Sbjct: 438 ERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSG-A 496
Query: 335 QLTSLTLSYNAVAELAPELFAD-LRALETFVMDGN 368
L L L N L D L++L ++GN
Sbjct: 497 PLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 531
Score = 38.7 bits (86), Expect = 0.035
Identities = 44/183 (24%), Positives = 78/183 (42%), Gaps = 6/183 (3%)
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQAL---PAGLFAST-PRLLNLTMMRNSFRYLD- 255
++I+ I AG N++ + + R+ L PA F T P L L++
Sbjct: 310 SKISGIVAGKALSNRNLSQIVSYQTRVPPLTPCPAPCFCKTHPSDLGLSVNCQEKNIQSM 369
Query: 256 SETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRT 314
SE + +++ ++ N + + F++ L L L + I + + N + LR
Sbjct: 370 SELIPKPLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRR 429
Query: 315 LSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVGY 374
L L NQ+ L + G L L L YN + E++ F + L+ ++ N L+
Sbjct: 430 LYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLP 489
Query: 375 VYI 377
VYI
Sbjct: 490 VYI 492
Score = 33.5 bits (73), Expect = 1.3
Identities = 24/102 (23%), Positives = 41/102 (40%), Gaps = 1/102 (0%)
Query: 268 IKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLP 326
+ NN L F N +L L + ++ + F+ S L+ L L N+L++L
Sbjct: 64 LNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILR 123
Query: 327 RSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
G L L YN + + F L L+ +++ N
Sbjct: 124 ADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDN 165
Score = 30.7 bits (66), Expect = 9.4
Identities = 28/122 (22%), Positives = 45/122 (36%), Gaps = 2/122 (1%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N + + AF GL + N + D + L + + + + F
Sbjct: 93 NKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLGIENLEYLQADYNLIKYIERGAFN 152
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANIT-AGAFRGLHNVTVLSLN 223
LK L L+D I+ LPD+ F + L L++ N I + G + V L L
Sbjct: 153 KLHKLKVLILNDNLISFLPDNIFRFAS-LTHLDIRGNRIQKLPYIGVLEHIGRVVELQLE 211
Query: 224 KN 225
N
Sbjct: 212 DN 213
>AK057619-1|BAB71535.1| 469|Homo sapiens protein ( Homo sapiens
cDNA FLJ33057 fis, clone TRACH1000144, weakly similar to
CHONDROADHERIN PRECURSOR. ).
Length = 469
Score = 66.5 bits (155), Expect = 2e-10
Identities = 42/152 (27%), Positives = 72/152 (47%), Gaps = 1/152 (0%)
Query: 194 EQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRY 253
++L+V N I ++ F + +L L N+I + +F + L L + N
Sbjct: 12 KKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIER 71
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLR 313
L E F GL ++Q + + N+ + F ++P L+ L L+ + ++ LP S +PL
Sbjct: 72 LYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAPLA 131
Query: 314 TLSLARNQLRVLPRSVLRGQTQ-LTSLTLSYN 344
L+L N+ LP S + Q Q LT + L N
Sbjct: 132 RLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 163
Score = 58.8 bits (136), Expect = 3e-08
Identities = 42/148 (28%), Positives = 68/148 (45%), Gaps = 2/148 (1%)
Query: 127 NAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDA 186
N + V V L L + + + ++F N L+ L L+ +I L +
Sbjct: 17 NGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEI 76
Query: 187 FLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTM 246
F GL+ L+ L + N I I+AG F + N+ +L LN N +++LP +F+ P L L +
Sbjct: 77 FSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP-LARLNL 135
Query: 247 MRNSFRYLD-SETFRGLDHIQEIKISNN 273
N F YL S L + +I + N
Sbjct: 136 RNNKFMYLPVSGVLDQLQSLTQIDLEGN 163
Score = 55.6 bits (128), Expect = 3e-07
Identities = 41/134 (30%), Positives = 60/134 (44%), Gaps = 2/134 (1%)
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
F + L L L +ITV+ D F L L +L + N+I + F GLHN+ L L
Sbjct: 29 FTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYL 88
Query: 223 NKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLK-EA 281
N I+ + AG F S P L L + N + L F G + + + NN + L
Sbjct: 89 EYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP-LARLNLRNNKFMYLPVSG 147
Query: 282 VFSNLPALRTLQLD 295
V L +L + L+
Sbjct: 148 VLDQLQSLTQIDLE 161
Score = 49.2 bits (112), Expect = 3e-05
Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 1/134 (0%)
Query: 170 KYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQA 229
K L ++ I + F L+ L++ N+I I F L N+ L LN N+I+
Sbjct: 12 KKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIER 71
Query: 230 LPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPAL 289
L +F+ L L + N + + + TF + ++Q + ++NN+ +L +FS P
Sbjct: 72 LYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAPLA 131
Query: 290 RTLQLDLSSIRELP 303
R L L + LP
Sbjct: 132 R-LNLRNNKFMYLP 144
Score = 43.2 bits (97), Expect = 0.002
Identities = 40/155 (25%), Positives = 66/155 (42%), Gaps = 3/155 (1%)
Query: 216 NVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVP 275
N L +N N I+ + F L L + N + + F L +++ + ++ N
Sbjct: 10 NAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQI 69
Query: 276 LTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQT 334
L +FS L L+ L L+ + I+E+ + P L+ L L N L+ LP + G
Sbjct: 70 ERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSG-A 128
Query: 335 QLTSLTLSYNAVAELAPELFAD-LRALETFVMDGN 368
L L L N L D L++L ++GN
Sbjct: 129 PLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 163
Score = 36.3 bits (80), Expect = 0.19
Identities = 28/113 (24%), Positives = 51/113 (45%), Gaps = 1/113 (0%)
Query: 266 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRV 324
+++ ++ N + + F++ L L L + I + + N + LR L L NQ+
Sbjct: 12 KKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIER 71
Query: 325 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVGYVYI 377
L + G L L L YN + E++ F + L+ ++ N L+ VYI
Sbjct: 72 LYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYI 124
>AF532859-1|AAP21836.1| 441|Homo sapiens Nogo-66 receptor homolog-2
protein.
Length = 441
Score = 66.5 bits (155), Expect = 2e-10
Identities = 51/167 (30%), Positives = 80/167 (47%), Gaps = 4/167 (2%)
Query: 155 NIT-LHANMFANTPPLKYLELSDAK-ITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR 212
NIT +H + F L+ L+L D + + L + F GL L L +++ ++ + AG F
Sbjct: 87 NITYIHPSTFEGFVHLEELDLGDNRQLRTLAPETFQGLVKLHALYLYKCGLSALPAGVFG 146
Query: 213 GLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISN 272
GLH++ L L N I+ L +F L +L + N L TFRGL ++ + +
Sbjct: 147 GLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLFLHGNKLWSLGPGTFRGLVNLDRLLLHE 206
Query: 273 NVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLAR 319
N + F +L L TL L +S+ EL E + +PL L R
Sbjct: 207 NQLQWVHHKAFHDLRRLTTLFLFNNSLSELQGECL--APLGALEFLR 251
Score = 63.3 bits (147), Expect = 1e-09
Identities = 47/173 (27%), Positives = 80/173 (46%), Gaps = 1/173 (0%)
Query: 102 VFKNAINPLNADAFKG-LGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHA 160
++ N I ++ F+G + + L + + T+ + + L KL L L A
Sbjct: 83 IYSNNITYIHPSTFEGFVHLEELDLGDNRQLRTLAPETFQGLVKLHALYLYKCGLSALPA 142
Query: 161 NMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVL 220
+F L+YL L D I L DD F+ L L L + N++ ++ G FRGL N+ L
Sbjct: 143 GVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLFLHGNKLWSLGPGTFRGLVNLDRL 202
Query: 221 SLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L++N++Q + F RL L + NS L E L ++ ++++ N
Sbjct: 203 LLHENQLQWVHHKAFHDLRRLTTLFLFNNSLSELQGECLAPLGALEFLRLNGN 255
Score = 57.6 bits (133), Expect = 7e-08
Identities = 45/152 (29%), Positives = 66/152 (43%), Gaps = 4/152 (2%)
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL-TLKE 280
L NRI L G F+ P ++ L + N+ Y+ TF G H++E+ + +N L TL
Sbjct: 61 LQNNRIGLLQPGHFS--PAMVTLWIYSNNITYIHPSTFEGFVHLEELDLGDNRQLRTLAP 118
Query: 281 AVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSL 339
F L L L L + LP F L+ L L N + L + L+ L
Sbjct: 119 ETFQGLVKLHALYLYKCGLSALPAGVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHL 178
Query: 340 TLSYNAVAELAPELFADLRALETFVMDGNELQ 371
L N + L P F L L+ ++ N+LQ
Sbjct: 179 FLHGNKLWSLGPGTFRGLVNLDRLLLHENQLQ 210
Score = 57.2 bits (132), Expect = 9e-08
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 2/178 (1%)
Query: 198 VWENEIANITAGAFRGLHNVTVLSLNKNR-IQALPAGLFASTPRLLNLTMMRNSFRYLDS 256
++ N I I F G ++ L L NR ++ L F +L L + + L +
Sbjct: 83 IYSNNITYIHPSTFEGFVHLEELDLGDNRQLRTLAPETFQGLVKLHALYLYKCGLSALPA 142
Query: 257 ETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTL 315
F GL +Q + + +N L++ +F +L L L L + + L P F L L
Sbjct: 143 GVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVNLSHLFLHGNKLWSLGPGTFRGLVNLDRL 202
Query: 316 SLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQVG 373
L NQL+ + +LT+L L N+++EL E A L ALE ++GN G
Sbjct: 203 LLHENQLQWVHHKAFHDLRRLTTLFLFNNSLSELQGECLAPLGALEFLRLNGNPWDCG 260
Score = 49.2 bits (112), Expect = 3e-05
Identities = 37/139 (26%), Positives = 62/139 (44%)
Query: 157 TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHN 216
TL F L L L ++ LP F GL+ L+ L + +N I + F L N
Sbjct: 115 TLAPETFQGLVKLHALYLYKCGLSALPAGVFGGLHSLQYLYLQDNHIEYLQDDIFVDLVN 174
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
++ L L+ N++ +L G F L L + N +++ + F L + + + NN
Sbjct: 175 LSHLFLHGNKLWSLGPGTFRGLVNLDRLLLHENQLQWVHHKAFHDLRRLTTLFLFNNSLS 234
Query: 277 TLKEAVFSNLPALRTLQLD 295
L+ + L AL L+L+
Sbjct: 235 ELQGECLAPLGALEFLRLN 253
>AF491944-1|AAL92176.1| 359|Homo sapiens decorin protein.
Length = 359
Score = 66.5 bits (155), Expect = 2e-10
Identities = 54/207 (26%), Positives = 97/207 (46%), Gaps = 9/207 (4%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P L+L + KIT + D F L L L + N+I+ ++ GAF L + L L+KN+
Sbjct: 81 PDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQ 140
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT---LKEAVF 283
++ LP + L L N + TF GL+ + I++ N PL ++ F
Sbjct: 141 LKELPEKM---PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTN-PLKSSGIENGAF 196
Query: 284 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+ L +++ ++I +P+ + L L L N++ + + L+G L L LS+
Sbjct: 197 QGMKKLSYIRIADTNITSIPQGLPPS--LTELHLDGNKISRVDAASLKGLNNLAKLGLSF 254
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
N+++ + A+ L +D N+L
Sbjct: 255 NSISAVDNGSLANTPHLRELHLDNNKL 281
Score = 59.7 bits (138), Expect = 2e-08
Identities = 54/227 (23%), Positives = 99/227 (43%), Gaps = 10/227 (4%)
Query: 105 NAINPLNADAFKGL-GITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N I + FK L + AL++ N P L KL L+ + L M
Sbjct: 91 NKITEIKDGDFKNLKNLHALILVNNKISKVSP-GAFTPLVKLERLYLSKNQLKELPEKM- 148
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEI--ANITAGAFRGLHNVTVLS 221
L+ L + +IT + F GLN + + + N + + I GAF+G+ ++ +
Sbjct: 149 --PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEA 281
+ I ++P GL P L L + N +D+ + +GL+++ ++ +S N +
Sbjct: 207 IADTNITSIPQGL---PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG 263
Query: 282 VFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRS 328
+N P LR L LD + + +P + ++ + L N + V+ S
Sbjct: 264 SLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSS 310
>AF138300-1|AAD44713.1| 359|Homo sapiens decorin variant A protein.
Length = 359
Score = 66.5 bits (155), Expect = 2e-10
Identities = 54/207 (26%), Positives = 97/207 (46%), Gaps = 9/207 (4%)
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNR 226
P L+L + KIT + D F L L L + N+I+ ++ GAF L + L L+KN+
Sbjct: 81 PDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQ 140
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT---LKEAVF 283
++ LP + L L N + TF GL+ + I++ N PL ++ F
Sbjct: 141 LKELPEKM---PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTN-PLKSSGIENGAF 196
Query: 284 SNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSY 343
+ L +++ ++I +P+ + L L L N++ + + L+G L L LS+
Sbjct: 197 QGMKKLSYIRIADTNITSIPQGLPPS--LTELHLDGNKISRVDAASLKGLNNLAKLGLSF 254
Query: 344 NAVAELAPELFADLRALETFVMDGNEL 370
N+++ + A+ L +D N+L
Sbjct: 255 NSISAVDNGSLANTPHLRELHLDNNKL 281
Score = 59.7 bits (138), Expect = 2e-08
Identities = 54/227 (23%), Positives = 99/227 (43%), Gaps = 10/227 (4%)
Query: 105 NAINPLNADAFKGL-GITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMF 163
N I + FK L + AL++ N P L KL L+ + L M
Sbjct: 91 NKITEIKDGDFKNLKNLHALILVNNKISKVSP-GAFTPLVKLERLYLSKNQLKELPEKM- 148
Query: 164 ANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEI--ANITAGAFRGLHNVTVLS 221
L+ L + +IT + F GLN + + + N + + I GAF+G+ ++ +
Sbjct: 149 --PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEA 281
+ I ++P GL P L L + N +D+ + +GL+++ ++ +S N +
Sbjct: 207 IADTNITSIPQGL---PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG 263
Query: 282 VFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRS 328
+N P LR L LD + + +P + ++ + L N + V+ S
Sbjct: 264 SLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSS 310
>BC068541-1|AAH68541.1| 713|Homo sapiens leucine rich repeat
neuronal 2 protein.
Length = 713
Score = 66.1 bits (154), Expect = 2e-10
Identities = 53/233 (22%), Positives = 106/233 (45%), Gaps = 3/233 (1%)
Query: 141 SLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
+LP+L L + L + FA L+ L L+ ++ + AF GL+ L +L++
Sbjct: 115 ALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNS 174
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
N + I + F L N+ +L + N++ A+ F L +L + + R +
Sbjct: 175 NLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALE 234
Query: 261 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLAR 319
GL ++ + +N + +P L+ L L+ + ++ + P +F + L+ L L
Sbjct: 235 GLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNN 294
Query: 320 -NQLRVLPRSVLRGQTQLTSLTLSYN-AVAELAPELFADLRALETFVMDGNEL 370
+L + + L +LT L ++ N ++ + P F L +ET +++ N L
Sbjct: 295 MEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNAL 347
Score = 62.9 bits (146), Expect = 2e-09
Identities = 50/204 (24%), Positives = 88/204 (43%), Gaps = 1/204 (0%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T ++ + + V L L LT L+ F P L L L + ++T
Sbjct: 71 TQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLT 130
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
L D +F GL L++L + N++ I AF GL N+ L LN N ++A+ + F P
Sbjct: 131 RLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPN 190
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIR 300
L L + N + FR L +++ + ++ + + L +L +L + +
Sbjct: 191 LEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLA 250
Query: 301 ELPEEFISNSP-LRTLSLARNQLR 323
+P + P L+ L L +N L+
Sbjct: 251 RVPRRALEQVPGLKFLDLNKNPLQ 274
Score = 56.4 bits (130), Expect = 2e-07
Identities = 63/273 (23%), Positives = 103/273 (37%), Gaps = 15/273 (5%)
Query: 79 RECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDV 138
R+C L LL +H E+ N + L +F GL + N +
Sbjct: 109 RDCDFHALPQLLS-LHLEE-------NQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRA 160
Query: 139 LRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
L L LN+ + + F P L+ L + K+ + D F L L L +
Sbjct: 161 FSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVL 220
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET 258
+ I+ A GL ++ LS N++ +P P L L + +N + +
Sbjct: 221 AGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGD 280
Query: 259 FRGLDHIQEIKISNNVPL-TLKEAVFSNLPALRTLQLD----LSSIRELPEEFISNSPLR 313
F + H++E+ ++N L ++ + NLP L L + LS I P F +
Sbjct: 281 FANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIH--PRAFHHLPQME 338
Query: 314 TLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAV 346
TL L N L L + L + L N +
Sbjct: 339 TLMLNNNALSALHQQTAESLPNLQEVGLHGNPI 371
Score = 43.6 bits (98), Expect = 0.001
Identities = 58/263 (22%), Positives = 97/263 (36%), Gaps = 26/263 (9%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITAL 123
+ D A QL SL L E L L A + + N + + AF GL
Sbjct: 110 DCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLR 169
Query: 124 MMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLP 183
+ N+ + LP L + + + F L+ L L+ + +
Sbjct: 170 LHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREIS 229
Query: 184 DDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFAST----- 238
D A GL LE L+ ++N++A + A + + L LNKN +Q + G FA+
Sbjct: 230 DYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKE 289
Query: 239 --------------------PRLLNLTMMRNS-FRYLDSETFRGLDHIQEIKISNNVPLT 277
P L L + N ++ F L ++ + ++NN
Sbjct: 290 LGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSA 349
Query: 278 LKEAVFSNLPALRTLQLDLSSIR 300
L + +LP L+ + L + IR
Sbjct: 350 LHQQTAESLPNLQEVGLHGNPIR 372
Score = 34.3 bits (75), Expect = 0.76
Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 1/107 (0%)
Query: 266 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRV 324
Q + + +N + + ++ L L L L +S + + +F + L +L L NQL
Sbjct: 72 QTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTR 131
Query: 325 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
L G L L L++N + +AP F+ L L ++ N L+
Sbjct: 132 LEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLR 178
>BC034047-1|AAH34047.1| 713|Homo sapiens leucine rich repeat
neuronal 2 protein.
Length = 713
Score = 66.1 bits (154), Expect = 2e-10
Identities = 53/233 (22%), Positives = 106/233 (45%), Gaps = 3/233 (1%)
Query: 141 SLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
+LP+L L + L + FA L+ L L+ ++ + AF GL+ L +L++
Sbjct: 115 ALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNS 174
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
N + I + F L N+ +L + N++ A+ F L +L + + R +
Sbjct: 175 NLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALE 234
Query: 261 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLAR 319
GL ++ + +N + +P L+ L L+ + ++ + P +F + L+ L L
Sbjct: 235 GLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNN 294
Query: 320 -NQLRVLPRSVLRGQTQLTSLTLSYN-AVAELAPELFADLRALETFVMDGNEL 370
+L + + L +LT L ++ N ++ + P F L +ET +++ N L
Sbjct: 295 MEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNAL 347
Score = 62.9 bits (146), Expect = 2e-09
Identities = 50/204 (24%), Positives = 88/204 (43%), Gaps = 1/204 (0%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T ++ + + V L L LT L+ F P L L L + ++T
Sbjct: 71 TQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLT 130
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
L D +F GL L++L + N++ I AF GL N+ L LN N ++A+ + F P
Sbjct: 131 RLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPN 190
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIR 300
L L + N + FR L +++ + ++ + + L +L +L + +
Sbjct: 191 LEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLA 250
Query: 301 ELPEEFISNSP-LRTLSLARNQLR 323
+P + P L+ L L +N L+
Sbjct: 251 RVPRRALEQVPGLKFLDLNKNPLQ 274
Score = 56.4 bits (130), Expect = 2e-07
Identities = 63/273 (23%), Positives = 103/273 (37%), Gaps = 15/273 (5%)
Query: 79 RECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDV 138
R+C L LL +H E+ N + L +F GL + N +
Sbjct: 109 RDCDFHALPQLLS-LHLEE-------NQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRA 160
Query: 139 LRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
L L LN+ + + F P L+ L + K+ + D F L L L +
Sbjct: 161 FSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVL 220
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET 258
+ I+ A GL ++ LS N++ +P P L L + +N + +
Sbjct: 221 AGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGD 280
Query: 259 FRGLDHIQEIKISNNVPL-TLKEAVFSNLPALRTLQLD----LSSIRELPEEFISNSPLR 313
F + H++E+ ++N L ++ + NLP L L + LS I P F +
Sbjct: 281 FANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIH--PRAFHHLPQME 338
Query: 314 TLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAV 346
TL L N L L + L + L N +
Sbjct: 339 TLMLNNNALSALHQQTAESLPNLQEVGLHGNPI 371
Score = 43.6 bits (98), Expect = 0.001
Identities = 58/263 (22%), Positives = 97/263 (36%), Gaps = 26/263 (9%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITAL 123
+ D A QL SL L E L L A + + N + + AF GL
Sbjct: 110 DCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLR 169
Query: 124 MMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLP 183
+ N+ + LP L + + + F L+ L L+ + +
Sbjct: 170 LHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREIS 229
Query: 184 DDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFAST----- 238
D A GL LE L+ ++N++A + A + + L LNKN +Q + G FA+
Sbjct: 230 DYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKE 289
Query: 239 --------------------PRLLNLTMMRNS-FRYLDSETFRGLDHIQEIKISNNVPLT 277
P L L + N ++ F L ++ + ++NN
Sbjct: 290 LGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSA 349
Query: 278 LKEAVFSNLPALRTLQLDLSSIR 300
L + +LP L+ + L + IR
Sbjct: 350 LHQQTAESLPNLQEVGLHGNPIR 372
Score = 34.3 bits (75), Expect = 0.76
Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 1/107 (0%)
Query: 266 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRV 324
Q + + +N + + ++ L L L L +S + + +F + L +L L NQL
Sbjct: 72 QTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTR 131
Query: 325 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
L G L L L++N + +AP F+ L L ++ N L+
Sbjct: 132 LEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLR 178
>AY358290-1|AAQ88657.1| 713|Homo sapiens GAC1 protein.
Length = 713
Score = 66.1 bits (154), Expect = 2e-10
Identities = 53/233 (22%), Positives = 106/233 (45%), Gaps = 3/233 (1%)
Query: 141 SLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
+LP+L L + L + FA L+ L L+ ++ + AF GL+ L +L++
Sbjct: 115 ALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNS 174
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
N + I + F L N+ +L + N++ A+ F L +L + + R +
Sbjct: 175 NLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALE 234
Query: 261 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLAR 319
GL ++ + +N + +P L+ L L+ + ++ + P +F + L+ L L
Sbjct: 235 GLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNN 294
Query: 320 -NQLRVLPRSVLRGQTQLTSLTLSYN-AVAELAPELFADLRALETFVMDGNEL 370
+L + + L +LT L ++ N ++ + P F L +ET +++ N L
Sbjct: 295 MEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNAL 347
Score = 62.9 bits (146), Expect = 2e-09
Identities = 50/204 (24%), Positives = 88/204 (43%), Gaps = 1/204 (0%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T ++ + + V L L LT L+ F P L L L + ++T
Sbjct: 71 TQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLT 130
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
L D +F GL L++L + N++ I AF GL N+ L LN N ++A+ + F P
Sbjct: 131 RLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPN 190
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIR 300
L L + N + FR L +++ + ++ + + L +L +L + +
Sbjct: 191 LEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLA 250
Query: 301 ELPEEFISNSP-LRTLSLARNQLR 323
+P + P L+ L L +N L+
Sbjct: 251 RVPRRALEQVPGLKFLDLNKNPLQ 274
Score = 57.2 bits (132), Expect = 9e-08
Identities = 63/273 (23%), Positives = 104/273 (38%), Gaps = 15/273 (5%)
Query: 79 RECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDV 138
R+C L LL +H E+ N + L +F GL + N +
Sbjct: 109 RDCDFHALPQLLS-LHLEE-------NQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRA 160
Query: 139 LRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
L L LN+ + + F P L+ L + K+ + D F L L L +
Sbjct: 161 FSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVL 220
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET 258
+ I+ A GL ++ LS N++ +P P L L + +N + +
Sbjct: 221 AGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGD 280
Query: 259 FRGLDHIQEIKISNNVPL-TLKEAVFSNLPALRTLQLD----LSSIRELPEEFISNSPLR 313
F + H++E+ ++N L ++ + NLP L L + LS I P F +
Sbjct: 281 FANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIH--PRAFHHLPQME 338
Query: 314 TLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAV 346
TL L N L L + + L + L N +
Sbjct: 339 TLMLNNNALSALHQQTVESLPNLQEVGLHGNPI 371
Score = 44.0 bits (99), Expect = 0.001
Identities = 58/263 (22%), Positives = 97/263 (36%), Gaps = 26/263 (9%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITAL 123
+ D A QL SL L E L L A + + N + + AF GL
Sbjct: 110 DCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLR 169
Query: 124 MMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLP 183
+ N+ + LP L + + + F L+ L L+ + +
Sbjct: 170 LHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREIS 229
Query: 184 DDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFAST----- 238
D A GL LE L+ ++N++A + A + + L LNKN +Q + G FA+
Sbjct: 230 DYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKE 289
Query: 239 --------------------PRLLNLTMMRNS-FRYLDSETFRGLDHIQEIKISNNVPLT 277
P L L + N ++ F L ++ + ++NN
Sbjct: 290 LGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSA 349
Query: 278 LKEAVFSNLPALRTLQLDLSSIR 300
L + +LP L+ + L + IR
Sbjct: 350 LHQQTVESLPNLQEVGLHGNPIR 372
Score = 34.3 bits (75), Expect = 0.76
Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 1/107 (0%)
Query: 266 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRV 324
Q + + +N + + ++ L L L L +S + + +F + L +L L NQL
Sbjct: 72 QTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTR 131
Query: 325 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
L G L L L++N + +AP F+ L L ++ N L+
Sbjct: 132 LEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLR 178
>AL512306-1|CAI14096.1| 713|Homo sapiens leucine rich repeat
neuronal 5 protein.
Length = 713
Score = 66.1 bits (154), Expect = 2e-10
Identities = 53/233 (22%), Positives = 106/233 (45%), Gaps = 3/233 (1%)
Query: 141 SLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
+LP+L L + L + FA L+ L L+ ++ + AF GL+ L +L++
Sbjct: 115 ALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNS 174
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
N + I + F L N+ +L + N++ A+ F L +L + + R +
Sbjct: 175 NLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALE 234
Query: 261 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLAR 319
GL ++ + +N + +P L+ L L+ + ++ + P +F + L+ L L
Sbjct: 235 GLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNN 294
Query: 320 -NQLRVLPRSVLRGQTQLTSLTLSYN-AVAELAPELFADLRALETFVMDGNEL 370
+L + + L +LT L ++ N ++ + P F L +ET +++ N L
Sbjct: 295 MEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNAL 347
Score = 62.9 bits (146), Expect = 2e-09
Identities = 50/204 (24%), Positives = 88/204 (43%), Gaps = 1/204 (0%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T ++ + + V L L LT L+ F P L L L + ++T
Sbjct: 71 TQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLT 130
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
L D +F GL L++L + N++ I AF GL N+ L LN N ++A+ + F P
Sbjct: 131 RLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPN 190
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIR 300
L L + N + FR L +++ + ++ + + L +L +L + +
Sbjct: 191 LEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLA 250
Query: 301 ELPEEFISNSP-LRTLSLARNQLR 323
+P + P L+ L L +N L+
Sbjct: 251 RVPRRALEQVPGLKFLDLNKNPLQ 274
Score = 57.2 bits (132), Expect = 9e-08
Identities = 63/273 (23%), Positives = 104/273 (38%), Gaps = 15/273 (5%)
Query: 79 RECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDV 138
R+C L LL +H E+ N + L +F GL + N +
Sbjct: 109 RDCDFHALPQLLS-LHLEE-------NQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRA 160
Query: 139 LRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
L L LN+ + + F P L+ L + K+ + D F L L L +
Sbjct: 161 FSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVL 220
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET 258
+ I+ A GL ++ LS N++ +P P L L + +N + +
Sbjct: 221 AGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGD 280
Query: 259 FRGLDHIQEIKISNNVPL-TLKEAVFSNLPALRTLQLD----LSSIRELPEEFISNSPLR 313
F + H++E+ ++N L ++ + NLP L L + LS I P F +
Sbjct: 281 FANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIH--PRAFHHLPQME 338
Query: 314 TLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAV 346
TL L N L L + + L + L N +
Sbjct: 339 TLMLNNNALSALHQQTVESLPNLQEVGLHGNPI 371
Score = 44.0 bits (99), Expect = 0.001
Identities = 58/263 (22%), Positives = 97/263 (36%), Gaps = 26/263 (9%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITAL 123
+ D A QL SL L E L L A + + N + + AF GL
Sbjct: 110 DCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLR 169
Query: 124 MMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLP 183
+ N+ + LP L + + + F L+ L L+ + +
Sbjct: 170 LHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREIS 229
Query: 184 DDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFAST----- 238
D A GL LE L+ ++N++A + A + + L LNKN +Q + G FA+
Sbjct: 230 DYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKE 289
Query: 239 --------------------PRLLNLTMMRNS-FRYLDSETFRGLDHIQEIKISNNVPLT 277
P L L + N ++ F L ++ + ++NN
Sbjct: 290 LGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSA 349
Query: 278 LKEAVFSNLPALRTLQLDLSSIR 300
L + +LP L+ + L + IR
Sbjct: 350 LHQQTVESLPNLQEVGLHGNPIR 372
Score = 34.3 bits (75), Expect = 0.76
Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 1/107 (0%)
Query: 266 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRV 324
Q + + +N + + ++ L L L L +S + + +F + L +L L NQL
Sbjct: 72 QTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTR 131
Query: 325 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
L G L L L++N + +AP F+ L L ++ N L+
Sbjct: 132 LEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLR 178
>AF030435-1|AAC39792.1| 713|Homo sapiens glioma amplified on
chromosome 1 protein protein.
Length = 713
Score = 66.1 bits (154), Expect = 2e-10
Identities = 53/233 (22%), Positives = 106/233 (45%), Gaps = 3/233 (1%)
Query: 141 SLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
+LP+L L + L + FA L+ L L+ ++ + AF GL+ L +L++
Sbjct: 115 ALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNS 174
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFR 260
N + I + F L N+ +L + N++ A+ F L +L + + R +
Sbjct: 175 NLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALE 234
Query: 261 GLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLAR 319
GL ++ + +N + +P L+ L L+ + ++ + P +F + L+ L L
Sbjct: 235 GLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNN 294
Query: 320 -NQLRVLPRSVLRGQTQLTSLTLSYN-AVAELAPELFADLRALETFVMDGNEL 370
+L + + L +LT L ++ N ++ + P F L +ET +++ N L
Sbjct: 295 MEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNAL 347
Score = 62.9 bits (146), Expect = 2e-09
Identities = 50/204 (24%), Positives = 88/204 (43%), Gaps = 1/204 (0%)
Query: 121 TALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKIT 180
T ++ + + V L L LT L+ F P L L L + ++T
Sbjct: 71 TQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLT 130
Query: 181 VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPR 240
L D +F GL L++L + N++ I AF GL N+ L LN N ++A+ + F P
Sbjct: 131 RLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPN 190
Query: 241 LLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIR 300
L L + N + FR L +++ + ++ + + L +L +L + +
Sbjct: 191 LEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLA 250
Query: 301 ELPEEFISNSP-LRTLSLARNQLR 323
+P + P L+ L L +N L+
Sbjct: 251 RVPRRALEQVPGLKFLDLNKNPLQ 274
Score = 57.2 bits (132), Expect = 9e-08
Identities = 63/273 (23%), Positives = 104/273 (38%), Gaps = 15/273 (5%)
Query: 79 RECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDV 138
R+C L LL +H E+ N + L +F GL + N +
Sbjct: 109 RDCDFHALPQLLS-LHLEE-------NQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRA 160
Query: 139 LRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNV 198
L L LN+ + + F P L+ L + K+ + D F L L L +
Sbjct: 161 FSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVL 220
Query: 199 WENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET 258
+ I+ A GL ++ LS N++ +P P L L + +N + +
Sbjct: 221 AGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGD 280
Query: 259 FRGLDHIQEIKISNNVPL-TLKEAVFSNLPALRTLQLD----LSSIRELPEEFISNSPLR 313
F + H++E+ ++N L ++ + NLP L L + LS I P F +
Sbjct: 281 FANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIH--PRAFHHLPQME 338
Query: 314 TLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAV 346
TL L N L L + + L + L N +
Sbjct: 339 TLMLNNNALSALHQQTVESLPNLQEVGLHGNPI 371
Score = 44.0 bits (99), Expect = 0.001
Identities = 58/263 (22%), Positives = 97/263 (36%), Gaps = 26/263 (9%)
Query: 64 EIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVFKNAINPLNADAFKGLGITAL 123
+ D A QL SL L E L L A + + N + + AF GL
Sbjct: 110 DCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLR 169
Query: 124 MMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLP 183
+ N+ + LP L + + + F L+ L L+ + +
Sbjct: 170 LHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREIS 229
Query: 184 DDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFAST----- 238
D A GL LE L+ ++N++A + A + + L LNKN +Q + G FA+
Sbjct: 230 DYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKE 289
Query: 239 --------------------PRLLNLTMMRNS-FRYLDSETFRGLDHIQEIKISNNVPLT 277
P L L + N ++ F L ++ + ++NN
Sbjct: 290 LGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSA 349
Query: 278 LKEAVFSNLPALRTLQLDLSSIR 300
L + +LP L+ + L + IR
Sbjct: 350 LHQQTVESLPNLQEVGLHGNPIR 372
Score = 34.3 bits (75), Expect = 0.76
Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 1/107 (0%)
Query: 266 QEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRV 324
Q + + +N + + ++ L L L L +S + + +F + L +L L NQL
Sbjct: 72 QTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTR 131
Query: 325 LPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
L G L L L++N + +AP F+ L L ++ N L+
Sbjct: 132 LEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLR 178
>DQ355157-1|ABC79623.1| 334|Homo sapiens cytokeratin associated
protein protein.
Length = 334
Score = 65.7 bits (153), Expect = 3e-10
Identities = 38/126 (30%), Positives = 63/126 (50%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
L+ L L ++ LP AF G L++L++ EN + ++ AF GL + +L L+ N+++
Sbjct: 73 LRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLE 132
Query: 229 ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPA 288
AL G FA L NL++ N L+ L ++ + + +N L + LPA
Sbjct: 133 ALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPA 192
Query: 289 LRTLQL 294
L L L
Sbjct: 193 LDALHL 198
Score = 58.4 bits (135), Expect = 4e-08
Identities = 48/143 (33%), Positives = 66/143 (46%), Gaps = 4/143 (2%)
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
+ A+P GL + RL L + N R L F G +Q + + N ++ F L
Sbjct: 62 LPAVPPGL---SLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGL 118
Query: 287 PALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
AL+ L L + + L P F LR LSLA N+L L + L L SL+L N
Sbjct: 119 GALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNE 178
Query: 346 VAELAPELFADLRALETFVMDGN 368
+A LAP L L AL+ + GN
Sbjct: 179 LAALAPGLLGRLPALDALHLRGN 201
Score = 56.4 bits (130), Expect = 2e-07
Identities = 42/126 (33%), Positives = 58/126 (46%), Gaps = 1/126 (0%)
Query: 220 LSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLK 279
L L+ NR++ALP G FA L L + N + F GL +Q + +S N L
Sbjct: 76 LLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALA 135
Query: 280 EAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTS 338
F+ L ALR L L + + L + P LR+LSL N+L L +L L +
Sbjct: 136 PGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDA 195
Query: 339 LTLSYN 344
L L N
Sbjct: 196 LHLRGN 201
Score = 44.8 bits (101), Expect = 5e-04
Identities = 32/83 (38%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 289 LRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVA 347
LR L LD + +R LP F L+ L L N L + G L L LS N +
Sbjct: 73 LRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLE 132
Query: 348 ELAPELFADLRALETFVMDGNEL 370
LAP FA LRAL + GN L
Sbjct: 133 ALAPGTFAPLRALRNLSLAGNRL 155
Score = 41.1 bits (92), Expect = 0.007
Identities = 30/111 (27%), Positives = 49/111 (44%)
Query: 144 KLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEI 203
+L L+ R L FA L+ L+L + + + AF GL L+ L++ N++
Sbjct: 72 RLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQL 131
Query: 204 ANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
+ G F L + LSL NR+ L + P L +L++ N L
Sbjct: 132 EALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAAL 182
>AY324322-1|AAQ97217.1| 469|Homo sapiens leucine-rich repeat
neuronal 6A protein.
Length = 469
Score = 65.7 bits (153), Expect = 3e-10
Identities = 61/213 (28%), Positives = 94/213 (44%), Gaps = 7/213 (3%)
Query: 162 MFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLS 221
MF + LK LE+ D + + AF GLN LEQL + + + +I A LH + VL
Sbjct: 11 MFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLR 70
Query: 222 LNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET---FRGLDHIQEIKISNNVPLTL 278
L I A+ F RL L + + + YLD+ T GL ++ + I++ +
Sbjct: 71 LRHLNINAIRDYSFKRLYRLKVLEI--SHWPYLDTMTPNCLYGL-NLTSLSITHCNLTAV 127
Query: 279 KEAVFSNLPALRTLQLDLSSIRELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLT 337
+L LR L L + I + + L+ + L QL V+ RG L
Sbjct: 128 PYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLR 187
Query: 338 SLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
L +S N + L +F + LET ++D N L
Sbjct: 188 VLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 220
Score = 59.3 bits (137), Expect = 2e-08
Identities = 47/183 (25%), Positives = 80/183 (43%), Gaps = 2/183 (1%)
Query: 114 AFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLKYLE 173
AF GL + T++P + L L L RL + F LK LE
Sbjct: 35 AFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLE 94
Query: 174 LSD-AKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPA 232
+S + + + GLN L L++ + + A R L + L+L+ N I +
Sbjct: 95 ISHWPYLDTMTPNCLYGLN-LTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEG 153
Query: 233 GLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTL 292
+ RL + ++ ++ FRGL++++ + +S N TL+E+VF ++ L TL
Sbjct: 154 SMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETL 213
Query: 293 QLD 295
LD
Sbjct: 214 ILD 216
Score = 48.0 bits (109), Expect = 6e-05
Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 1/119 (0%)
Query: 107 INPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANT 166
++ + + GL +T+L + + T VP +R L L L+ T+ +M
Sbjct: 101 LDTMTPNCLYGLNLTSLSITHCNL-TAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHEL 159
Query: 167 PPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
L+ ++L ++ V+ AF GLN L LNV N++ + F + N+ L L+ N
Sbjct: 160 LRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSN 218
Score = 43.2 bits (97), Expect = 0.002
Identities = 35/174 (20%), Positives = 75/174 (43%), Gaps = 1/174 (0%)
Query: 200 ENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETF 259
EN+I + F+ L+N+ L + N + + F+ L LT+ + + + +E
Sbjct: 1 ENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEAL 60
Query: 260 RGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLD-LSSIRELPEEFISNSPLRTLSLA 318
L + +++ + +++ F L L+ L++ + + + L +LS+
Sbjct: 61 SHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLNLTSLSIT 120
Query: 319 RNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 372
L +P +R L L LSYN ++ + + +L L+ + G +L V
Sbjct: 121 HCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAV 174
>AL929554-11|CAH72880.1| 334|Homo sapiens leucine rich repeat
containing 26 protein.
Length = 334
Score = 65.7 bits (153), Expect = 3e-10
Identities = 38/126 (30%), Positives = 63/126 (50%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
L+ L L ++ LP AF G L++L++ EN + ++ AF GL + +L L+ N+++
Sbjct: 73 LRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLE 132
Query: 229 ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPA 288
AL G FA L NL++ N L+ L ++ + + +N L + LPA
Sbjct: 133 ALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPA 192
Query: 289 LRTLQL 294
L L L
Sbjct: 193 LDALHL 198
Score = 58.4 bits (135), Expect = 4e-08
Identities = 48/143 (33%), Positives = 66/143 (46%), Gaps = 4/143 (2%)
Query: 227 IQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNL 286
+ A+P GL + RL L + N R L F G +Q + + N ++ F L
Sbjct: 62 LPAVPPGL---SLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGL 118
Query: 287 PALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNA 345
AL+ L L + + L P F LR LSLA N+L L + L L SL+L N
Sbjct: 119 GALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNE 178
Query: 346 VAELAPELFADLRALETFVMDGN 368
+A LAP L L AL+ + GN
Sbjct: 179 LAALAPGLLGRLPALDALHLRGN 201
Score = 56.4 bits (130), Expect = 2e-07
Identities = 42/126 (33%), Positives = 58/126 (46%), Gaps = 1/126 (0%)
Query: 220 LSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLK 279
L L+ NR++ALP G FA L L + N + F GL +Q + +S N L
Sbjct: 76 LLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALA 135
Query: 280 EAVFSNLPALRTLQLDLSSIRELPEEFISNSP-LRTLSLARNQLRVLPRSVLRGQTQLTS 338
F+ L ALR L L + + L + P LR+LSL N+L L +L L +
Sbjct: 136 PGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDA 195
Query: 339 LTLSYN 344
L L N
Sbjct: 196 LHLRGN 201
Score = 44.8 bits (101), Expect = 5e-04
Identities = 32/83 (38%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 289 LRTLQLDLSSIRELPE-EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVA 347
LR L LD + +R LP F L+ L L N L + G L L LS N +
Sbjct: 73 LRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLE 132
Query: 348 ELAPELFADLRALETFVMDGNEL 370
LAP FA LRAL + GN L
Sbjct: 133 ALAPGTFAPLRALRNLSLAGNRL 155
Score = 41.1 bits (92), Expect = 0.007
Identities = 30/111 (27%), Positives = 49/111 (44%)
Query: 144 KLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEI 203
+L L+ R L FA L+ L+L + + + AF GL L+ L++ N++
Sbjct: 72 RLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQL 131
Query: 204 ANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
+ G F L + LSL NR+ L + P L +L++ N L
Sbjct: 132 EALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAAL 182
>BC087848-1|AAH87848.1| 261|Homo sapiens LGI4 protein protein.
Length = 261
Score = 65.3 bits (152), Expect = 4e-10
Identities = 35/95 (36%), Positives = 52/95 (54%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L A F P L L + +V+ DDAF GL+ L+ L + +NEI +I+ A RGL ++
Sbjct: 67 LKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSL 126
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
T LSL N ++ LP LF L ++ + N F+
Sbjct: 127 THLSLANNHLETLPRFLFRGLDTLTHVDLRGNPFQ 161
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/84 (30%), Positives = 40/84 (47%)
Query: 220 LSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLK 279
LSL + + L AG F P L L NSF ++ + F GL H+Q + I +N ++
Sbjct: 57 LSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSIS 116
Query: 280 EAVFSNLPALRTLQLDLSSIRELP 303
+ L +L L L + + LP
Sbjct: 117 KNALRGLRSLTHLSLANNHLETLP 140
Score = 39.5 bits (88), Expect = 0.020
Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
LK F +P+L L +S + ++ F S L+ L + N++ + ++ LRG L
Sbjct: 67 LKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSL 126
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
T L+L+ N + L LF L L + GN Q
Sbjct: 127 THLSLANNHLETLPRFLFRGLDTLTHVDLRGNPFQ 161
Score = 37.1 bits (82), Expect = 0.11
Identities = 23/87 (26%), Positives = 38/87 (43%)
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
+P L + + + FA L+YL + D +I + +A GL L L++ N
Sbjct: 75 IPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANN 134
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQ 228
+ + FRGL +T + L N Q
Sbjct: 135 HLETLPRFLFRGLDTLTHVDLRGNPFQ 161
Score = 35.1 bits (77), Expect = 0.44
Identities = 23/102 (22%), Positives = 41/102 (40%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
L L++ + + AG+F + ++ +L N + FA L L + N
Sbjct: 54 LLSLSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIG 113
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
+ RGL + + ++NN TL +F L L + L
Sbjct: 114 SISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLTHVDL 155
Score = 31.9 bits (69), Expect = 4.1
Identities = 28/124 (22%), Positives = 48/124 (38%), Gaps = 2/124 (1%)
Query: 52 CMGGELVCAEFPEIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVF-KNAINPL 110
C +C P++ + L SLSL + L + + ++F N+ + +
Sbjct: 33 CSKDSALCEGSPDLPVSFSPTLLSLSLVRTGVTQLKAG-SFLRIPSLHLLLFTSNSFSVI 91
Query: 111 NADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLK 170
DAF GL + ++ + LR L LTH L TL +F L
Sbjct: 92 EDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLT 151
Query: 171 YLEL 174
+++L
Sbjct: 152 HVDL 155
>BC030608-1|AAH30608.1| 661|Homo sapiens podocan protein.
Length = 661
Score = 65.3 bits (152), Expect = 4e-10
Identities = 63/237 (26%), Positives = 105/237 (44%), Gaps = 18/237 (7%)
Query: 146 THFRLNAGRNITLHANMFANTPP-----LKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
T ++L++ + L +N + P L L L I + + + LE L +
Sbjct: 331 TFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHS 390
Query: 201 NEIAN--ITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET 258
N++ I AF+GL + + L N ++ +P+GL R+ L ++ N + E
Sbjct: 391 NQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGL---PRRVRTLMILHNQITGIGRED 447
Query: 259 FRGLDHIQEIKISNN---VPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
F ++E+ +S N P ++A F L LR+L L + + LP N + L
Sbjct: 448 FATTYFLEELNLSYNRITSPQVHRDA-FRKLRLLRSLDLSGNRLHTLPPGLPRN--VHVL 504
Query: 316 SLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRALETFVMDGNEL 370
+ RN+L L R L G QL L L+ N + L P + DL L+ + GN+L
Sbjct: 505 KVKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQL 561
Score = 50.4 bits (115), Expect = 1e-05
Identities = 54/214 (25%), Positives = 93/214 (43%), Gaps = 14/214 (6%)
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
F + L YL L++ K+T+ P FL N L ++ N + I F N+ + L
Sbjct: 190 FEHLTNLNYLYLANNKLTLAP--RFLP-NALISVDFAANYLTKIYGLTFGQKPNLRSVYL 246
Query: 223 NKNRIQ--ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKE 280
+ N++ LP +F + + L + N R++ L ++ + NN +
Sbjct: 247 HNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPAL---YKLHLKNNKLEKIPP 303
Query: 281 AVFSNLPALRTLQLDLSSIRELP---EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLT 337
FS L +LR L L + + + E F S L L L+ N L +P + R L
Sbjct: 304 GAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRS---LV 360
Query: 338 SLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
L L NA+ + + +R+LE ++ N+L+
Sbjct: 361 LLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLR 394
Score = 44.8 bits (101), Expect = 5e-04
Identities = 46/171 (26%), Positives = 73/171 (42%), Gaps = 14/171 (8%)
Query: 110 LNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRN--ITLHANMFANTP 167
++ DAF+ L + + + T+P LP+ H L RN L A
Sbjct: 469 VHRDAFRKLRLLRSLDLSGNRLHTLPP----GLPRNVHV-LKVKRNELAALARGALAGMA 523
Query: 168 PLKYLELSDAKIT--VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
L+ L L+ ++ L A++ L L+ L++ N++ I G L L L N
Sbjct: 524 QLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLE---YLYLQNN 580
Query: 226 RIQALPAGLFASTPRLLNLTMMRNSFRY--LDSETFRGLDHIQEIKISNNV 274
+I A+PA F STP L + + N + FR L H+Q + I N+
Sbjct: 581 KISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGNL 631
Score = 38.7 bits (86), Expect = 0.035
Identities = 42/180 (23%), Positives = 76/180 (42%), Gaps = 11/180 (6%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRI--QALPAGLFASTPRLLNLTMMRNSFRY 253
L++ N++ I LH + L+L NR+ + LP F L L + N
Sbjct: 149 LSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTL 208
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRE--LPEE-FISNS 310
+ F + + + + N + F P LR++ L + + + LP+ F +S
Sbjct: 209 --APRFLP-NALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSS 265
Query: 311 PLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ L L+ N LR +P+ + L L L N + ++ P F++L +L + N L
Sbjct: 266 NVEVLILSSNFLRHVPKHL---PPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYL 322
>BC028292-1|AAH28292.1| 402|Homo sapiens PODN protein protein.
Length = 402
Score = 65.3 bits (152), Expect = 4e-10
Identities = 63/237 (26%), Positives = 105/237 (44%), Gaps = 18/237 (7%)
Query: 146 THFRLNAGRNITLHANMFANTPP-----LKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
T ++L++ + L +N + P L L L I + + + LE L +
Sbjct: 72 TFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHS 131
Query: 201 NEIAN--ITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET 258
N++ I AF+GL + + L N ++ +P+GL R+ L ++ N + E
Sbjct: 132 NQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGL---PRRVRTLMILHNQITGIGRED 188
Query: 259 FRGLDHIQEIKISNN---VPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
F ++E+ +S N P ++A F L LR+L L + + LP N + L
Sbjct: 189 FATTYFLEELNLSYNRITSPQVHRDA-FRKLRLLRSLDLSGNRLHTLPPGLPRN--VHVL 245
Query: 316 SLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRALETFVMDGNEL 370
+ RN+L L R L G QL L L+ N + L P + DL L+ + GN+L
Sbjct: 246 KVKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQL 302
Score = 44.8 bits (101), Expect = 5e-04
Identities = 46/171 (26%), Positives = 73/171 (42%), Gaps = 14/171 (8%)
Query: 110 LNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRN--ITLHANMFANTP 167
++ DAF+ L + + + T+P LP+ H L RN L A
Sbjct: 210 VHRDAFRKLRLLRSLDLSGNRLHTLPP----GLPRNVHV-LKVKRNELAALARGALAGMA 264
Query: 168 PLKYLELSDAKIT--VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
L+ L L+ ++ L A++ L L+ L++ N++ I G L L L N
Sbjct: 265 QLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLE---YLYLQNN 321
Query: 226 RIQALPAGLFASTPRLLNLTMMRNSFRY--LDSETFRGLDHIQEIKISNNV 274
+I A+PA F STP L + + N + FR L H+Q + I N+
Sbjct: 322 KISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGNL 372
Score = 37.9 bits (84), Expect = 0.062
Identities = 42/149 (28%), Positives = 72/149 (48%), Gaps = 14/149 (9%)
Query: 220 LSLNKNRIQALPAGLFASTPRLLNLTMMRNSF--RYLDSETFRGLDHIQEIKISNNVPLT 277
L L N+++ +P G F+ L L + N LD+ETF L ++ + +S+N
Sbjct: 32 LHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSN---N 88
Query: 278 LKEAVFSNLP-ALRTLQLDLSSIRELPEEFISNSPLRTLS---LARNQLRV--LPRSVLR 331
L V + LP +L L L+ ++IR + + +P+R+L L NQLR + +
Sbjct: 89 LSR-VPAGLPRSLVLLHLEKNAIRSVDANVL--TPIRSLEYLLLHSNQLREQGIHPLAFQ 145
Query: 332 GQTQLTSLTLSYNAVAELAPELFADLRAL 360
G +L ++ L NA+ + L +R L
Sbjct: 146 GLKRLHTVHLYNNALERVPSGLPRRVRTL 174
Score = 36.3 bits (80), Expect = 0.19
Identities = 29/110 (26%), Positives = 50/110 (45%), Gaps = 6/110 (5%)
Query: 265 IQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELP---EEFISNSPLRTLSLARNQ 321
+ ++ + NN + FS L +LR L L + + + E F S L L L+ N
Sbjct: 29 LYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNN 88
Query: 322 LRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
L +P + R L L L NA+ + + +R+LE ++ N+L+
Sbjct: 89 LSRVPAGLPRS---LVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLR 135
>AY358294-1|AAQ88661.1| 642|Homo sapiens EGEE293 protein.
Length = 642
Score = 65.3 bits (152), Expect = 4e-10
Identities = 63/237 (26%), Positives = 105/237 (44%), Gaps = 18/237 (7%)
Query: 146 THFRLNAGRNITLHANMFANTPP-----LKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
T ++L++ + L +N + P L L L I + + + LE L +
Sbjct: 312 TFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHS 371
Query: 201 NEIAN--ITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET 258
N++ I AF+GL + + L N ++ +P+GL R+ L ++ N + E
Sbjct: 372 NQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGL---PRRVRTLMILHNQITGIGRED 428
Query: 259 FRGLDHIQEIKISNN---VPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
F ++E+ +S N P ++A F L LR+L L + + LP N + L
Sbjct: 429 FATTYFLEELNLSYNRITSPQVHRDA-FRKLRLLRSLDLSGNRLHTLPPGLPRN--VHVL 485
Query: 316 SLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRALETFVMDGNEL 370
+ RN+L L R L G QL L L+ N + L P + DL L+ + GN+L
Sbjct: 486 KVKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQL 542
Score = 50.4 bits (115), Expect = 1e-05
Identities = 54/214 (25%), Positives = 93/214 (43%), Gaps = 14/214 (6%)
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
F + L YL L++ K+T+ P FL N L ++ N + I F N+ + L
Sbjct: 171 FEHLTNLNYLYLANNKLTLAP--RFLP-NALISVDFAANYLTKIYGLTFGQKPNLRSVYL 227
Query: 223 NKNRIQ--ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKE 280
+ N++ LP +F + + L + N R++ L ++ + NN +
Sbjct: 228 HNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPAL---YKLHLKNNKLEKIPP 284
Query: 281 AVFSNLPALRTLQLDLSSIRELP---EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLT 337
FS L +LR L L + + + E F S L L L+ N L +P + R L
Sbjct: 285 GAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRS---LV 341
Query: 338 SLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
L L NA+ + + +R+LE ++ N+L+
Sbjct: 342 LLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLR 375
Score = 44.8 bits (101), Expect = 5e-04
Identities = 46/171 (26%), Positives = 73/171 (42%), Gaps = 14/171 (8%)
Query: 110 LNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRN--ITLHANMFANTP 167
++ DAF+ L + + + T+P LP+ H L RN L A
Sbjct: 450 VHRDAFRKLRLLRSLDLSGNRLHTLPP----GLPRNVHV-LKVKRNELAALARGALAGMA 504
Query: 168 PLKYLELSDAKIT--VLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKN 225
L+ L L+ ++ L A++ L L+ L++ N++ I G L L L N
Sbjct: 505 QLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLE---YLYLQNN 561
Query: 226 RIQALPAGLFASTPRLLNLTMMRNSFRY--LDSETFRGLDHIQEIKISNNV 274
+I A+PA F STP L + + N + FR L H+Q + I N+
Sbjct: 562 KISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGNL 612
Score = 38.7 bits (86), Expect = 0.035
Identities = 42/180 (23%), Positives = 76/180 (42%), Gaps = 11/180 (6%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRI--QALPAGLFASTPRLLNLTMMRNSFRY 253
L++ N++ I LH + L+L NR+ + LP F L L + N
Sbjct: 130 LSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTL 189
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRE--LPEE-FISNS 310
+ F + + + + N + F P LR++ L + + + LP+ F +S
Sbjct: 190 --APRFLP-NALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSS 246
Query: 311 PLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ L L+ N LR +P+ + L L L N + ++ P F++L +L + N L
Sbjct: 247 NVEVLILSSNFLRHVPKHL---PPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYL 303
>AY358121-1|AAQ88488.1| 261|Homo sapiens LGI4 protein.
Length = 261
Score = 65.3 bits (152), Expect = 4e-10
Identities = 35/95 (36%), Positives = 52/95 (54%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L A F P L L + +V+ DDAF GL+ L+ L + +NEI +I+ A RGL ++
Sbjct: 67 LKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSL 126
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
T LSL N ++ LP LF L ++ + N F+
Sbjct: 127 THLSLANNHLETLPRFLFRGLDTLTHVDLRGNPFQ 161
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/84 (30%), Positives = 40/84 (47%)
Query: 220 LSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLK 279
LSL + + L AG F P L L NSF ++ + F GL H+Q + I +N ++
Sbjct: 57 LSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSIS 116
Query: 280 EAVFSNLPALRTLQLDLSSIRELP 303
+ L +L L L + + LP
Sbjct: 117 KNALRGLRSLTHLSLANNHLETLP 140
Score = 39.5 bits (88), Expect = 0.020
Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
LK F +P+L L +S + ++ F S L+ L + N++ + ++ LRG L
Sbjct: 67 LKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSL 126
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
T L+L+ N + L LF L L + GN Q
Sbjct: 127 THLSLANNHLETLPRFLFRGLDTLTHVDLRGNPFQ 161
Score = 37.1 bits (82), Expect = 0.11
Identities = 23/87 (26%), Positives = 38/87 (43%)
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
+P L + + + FA L+YL + D +I + +A GL L L++ N
Sbjct: 75 IPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANN 134
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQ 228
+ + FRGL +T + L N Q
Sbjct: 135 HLETLPRFLFRGLDTLTHVDLRGNPFQ 161
Score = 35.1 bits (77), Expect = 0.44
Identities = 23/102 (22%), Positives = 41/102 (40%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
L L++ + + AG+F + ++ +L N + FA L L + N
Sbjct: 54 LLSLSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIG 113
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
+ RGL + + ++NN TL +F L L + L
Sbjct: 114 SISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLTHVDL 155
Score = 31.9 bits (69), Expect = 4.1
Identities = 28/124 (22%), Positives = 48/124 (38%), Gaps = 2/124 (1%)
Query: 52 CMGGELVCAEFPEIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVF-KNAINPL 110
C +C P++ + L SLSL + L + + ++F N+ + +
Sbjct: 33 CSKDSALCEGSPDLPVSFSPTLLSLSLVRTGVTQLKAG-SFLRIPSLHLLLFTSNSFSVI 91
Query: 111 NADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLK 170
DAF GL + ++ + LR L LTH L TL +F L
Sbjct: 92 EDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLT 151
Query: 171 YLEL 174
+++L
Sbjct: 152 HVDL 155
>AJ487959-1|CAD32306.1| 537|Homo sapiens LGI1-like protein 3
protein.
Length = 537
Score = 65.3 bits (152), Expect = 4e-10
Identities = 35/95 (36%), Positives = 52/95 (54%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L A F P L L + +V+ DDAF GL+ L+ L + +NEI +I+ A RGL ++
Sbjct: 67 LKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSL 126
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
T LSL N ++ LP LF L ++ + N F+
Sbjct: 127 THLSLANNHLETLPRFLFRGLDTLTHVDLRGNPFQ 161
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/84 (30%), Positives = 40/84 (47%)
Query: 220 LSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLK 279
LSL + + L AG F P L L NSF ++ + F GL H+Q + I +N ++
Sbjct: 57 LSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSIS 116
Query: 280 EAVFSNLPALRTLQLDLSSIRELP 303
+ L +L L L + + LP
Sbjct: 117 KNALRGLRSLTHLSLANNHLETLP 140
Score = 39.5 bits (88), Expect = 0.020
Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
LK F +P+L L +S + ++ F S L+ L + N++ + ++ LRG L
Sbjct: 67 LKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSL 126
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
T L+L+ N + L LF L L + GN Q
Sbjct: 127 THLSLANNHLETLPRFLFRGLDTLTHVDLRGNPFQ 161
Score = 37.1 bits (82), Expect = 0.11
Identities = 23/87 (26%), Positives = 38/87 (43%)
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
+P L + + + FA L+YL + D +I + +A GL L L++ N
Sbjct: 75 IPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANN 134
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQ 228
+ + FRGL +T + L N Q
Sbjct: 135 HLETLPRFLFRGLDTLTHVDLRGNPFQ 161
Score = 35.1 bits (77), Expect = 0.44
Identities = 23/102 (22%), Positives = 41/102 (40%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
L L++ + + AG+F + ++ +L N + FA L L + N
Sbjct: 54 LLSLSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIG 113
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
+ RGL + + ++NN TL +F L L + L
Sbjct: 114 SISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLTHVDL 155
Score = 31.9 bits (69), Expect = 4.1
Identities = 28/124 (22%), Positives = 48/124 (38%), Gaps = 2/124 (1%)
Query: 52 CMGGELVCAEFPEIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVF-KNAINPL 110
C +C P++ + L SLSL + L + + ++F N+ + +
Sbjct: 33 CSKDSALCEGSPDLPVSFSPTLLSLSLVRTGVTQLKAG-SFLRIPSLHLLLFTSNSFSVI 91
Query: 111 NADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLK 170
DAF GL + ++ + LR L LTH L TL +F L
Sbjct: 92 EDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLT 151
Query: 171 YLEL 174
+++L
Sbjct: 152 HVDL 155
>AJ487519-1|CAD31787.1| 537|Homo sapiens leucine-rich glioma
inactivated protein 4 protein.
Length = 537
Score = 65.3 bits (152), Expect = 4e-10
Identities = 35/95 (36%), Positives = 52/95 (54%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L A F P L L + +V+ DDAF GL+ L+ L + +NEI +I+ A RGL ++
Sbjct: 67 LKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSL 126
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
T LSL N ++ LP LF L ++ + N F+
Sbjct: 127 THLSLANNHLETLPRFLFRGLDTLTHVDLRGNPFQ 161
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/84 (30%), Positives = 40/84 (47%)
Query: 220 LSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLK 279
LSL + + L AG F P L L NSF ++ + F GL H+Q + I +N ++
Sbjct: 57 LSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSIS 116
Query: 280 EAVFSNLPALRTLQLDLSSIRELP 303
+ L +L L L + + LP
Sbjct: 117 KNALRGLRSLTHLSLANNHLETLP 140
Score = 39.5 bits (88), Expect = 0.020
Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
LK F +P+L L +S + ++ F S L+ L + N++ + ++ LRG L
Sbjct: 67 LKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSL 126
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
T L+L+ N + L LF L L + GN Q
Sbjct: 127 THLSLANNHLETLPRFLFRGLDTLTHVDLRGNPFQ 161
Score = 37.1 bits (82), Expect = 0.11
Identities = 23/87 (26%), Positives = 38/87 (43%)
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
+P L + + + FA L+YL + D +I + +A GL L L++ N
Sbjct: 75 IPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANN 134
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQ 228
+ + FRGL +T + L N Q
Sbjct: 135 HLETLPRFLFRGLDTLTHVDLRGNPFQ 161
Score = 35.1 bits (77), Expect = 0.44
Identities = 23/102 (22%), Positives = 41/102 (40%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
L L++ + + AG+F + ++ +L N + FA L L + N
Sbjct: 54 LLSLSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIG 113
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
+ RGL + + ++NN TL +F L L + L
Sbjct: 114 SISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLTHVDL 155
Score = 31.9 bits (69), Expect = 4.1
Identities = 28/124 (22%), Positives = 48/124 (38%), Gaps = 2/124 (1%)
Query: 52 CMGGELVCAEFPEIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVF-KNAINPL 110
C +C P++ + L SLSL + L + + ++F N+ + +
Sbjct: 33 CSKDSALCEGSPDLPVSFSPTLLSLSLVRTGVTQLKAG-SFLRIPSLHLLLFTSNSFSVI 91
Query: 111 NADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLK 170
DAF GL + ++ + LR L LTH L TL +F L
Sbjct: 92 EDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLT 151
Query: 171 YLEL 174
+++L
Sbjct: 152 HVDL 155
>AF467954-1|AAM49552.1| 537|Homo sapiens LGI4 protein.
Length = 537
Score = 65.3 bits (152), Expect = 4e-10
Identities = 35/95 (36%), Positives = 52/95 (54%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L A F P L L + +V+ DDAF GL+ L+ L + +NEI +I+ A RGL ++
Sbjct: 67 LKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSL 126
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
T LSL N ++ LP LF L ++ + N F+
Sbjct: 127 THLSLANNHLETLPRFLFRGLDTLTHVDLRGNPFQ 161
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/84 (30%), Positives = 40/84 (47%)
Query: 220 LSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLK 279
LSL + + L AG F P L L NSF ++ + F GL H+Q + I +N ++
Sbjct: 57 LSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSIS 116
Query: 280 EAVFSNLPALRTLQLDLSSIRELP 303
+ L +L L L + + LP
Sbjct: 117 KNALRGLRSLTHLSLANNHLETLP 140
Score = 39.5 bits (88), Expect = 0.020
Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Query: 278 LKEAVFSNLPALRTLQLDLSSIRELPEE-FISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
LK F +P+L L +S + ++ F S L+ L + N++ + ++ LRG L
Sbjct: 67 LKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSL 126
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
T L+L+ N + L LF L L + GN Q
Sbjct: 127 THLSLANNHLETLPRFLFRGLDTLTHVDLRGNPFQ 161
Score = 37.1 bits (82), Expect = 0.11
Identities = 23/87 (26%), Positives = 38/87 (43%)
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
+P L + + + FA L+YL + D +I + +A GL L L++ N
Sbjct: 75 IPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANN 134
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQ 228
+ + FRGL +T + L N Q
Sbjct: 135 HLETLPRFLFRGLDTLTHVDLRGNPFQ 161
Score = 35.1 bits (77), Expect = 0.44
Identities = 23/102 (22%), Positives = 41/102 (40%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
L L++ + + AG+F + ++ +L N + FA L L + N
Sbjct: 54 LLSLSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIG 113
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
+ RGL + + ++NN TL +F L L + L
Sbjct: 114 SISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLTHVDL 155
Score = 31.9 bits (69), Expect = 4.1
Identities = 28/124 (22%), Positives = 48/124 (38%), Gaps = 2/124 (1%)
Query: 52 CMGGELVCAEFPEIDTPATTQLPSLSLRECSLPPLSCLLQKVHAEDVKTVVF-KNAINPL 110
C +C P++ + L SLSL + L + + ++F N+ + +
Sbjct: 33 CSKDSALCEGSPDLPVSFSPTLLSLSLVRTGVTQLKAG-SFLRIPSLHLLLFTSNSFSVI 91
Query: 111 NADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFANTPPLK 170
DAF GL + ++ + LR L LTH L TL +F L
Sbjct: 92 EDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLT 151
Query: 171 YLEL 174
+++L
Sbjct: 152 HVDL 155
>BC080586-1|AAH80586.1| 743|Homo sapiens MXRA5 protein protein.
Length = 743
Score = 64.9 bits (151), Expect = 5e-10
Identities = 44/161 (27%), Positives = 77/161 (47%), Gaps = 9/161 (5%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
+E++N+ N I ++ +F GL + +L ++ N I ++P G L N R
Sbjct: 57 VERINLGFNSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRDLSSLQVFKFSYNKLR 116
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE------- 304
+ +T +GL ++ + I +N + F+ L +LR L L+ + + +L P
Sbjct: 117 VITGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGNLLHQLHPSTFSTFTF 176
Query: 305 -EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
++ S +R L LA N +R LP S+LR L +L L N
Sbjct: 177 LDYFRLSTIRHLYLAENMVRTLPASMLRNMPLLENLYLQGN 217
Score = 52.0 bits (119), Expect = 4e-06
Identities = 33/122 (27%), Positives = 58/122 (47%), Gaps = 1/122 (0%)
Query: 250 SFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN 309
+FR L S H++ I + N L E F+ L L L + + I +P+ + +
Sbjct: 42 TFRSLASVPAGIAKHVERINLGFNSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRD 101
Query: 310 -SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
S L+ + N+LRV+ L+G + L L + +N + + P+ F L +L ++GN
Sbjct: 102 LSSLQVFKFSYNKLRVITGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGN 161
Query: 369 EL 370
L
Sbjct: 162 LL 163
Score = 48.0 bits (109), Expect = 6e-05
Identities = 42/156 (26%), Positives = 68/156 (43%), Gaps = 10/156 (6%)
Query: 149 RLNAGRNI--TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANI 206
R+N G N L FA L+ L + +I +PD A L+ L+ N++ I
Sbjct: 59 RINLGFNSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRDLSSLQVFKFSYNKLRVI 118
Query: 207 TAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG---LD 263
T +GL N+ L ++ N+I+ + F L L + N L TF LD
Sbjct: 119 TGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGNLLHQLHPSTFSTFTFLD 178
Query: 264 H-----IQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
+ I+ + ++ N+ TL ++ N+P L L L
Sbjct: 179 YFRLSTIRHLYLAENMVRTLPASMLRNMPLLENLYL 214
Score = 46.4 bits (105), Expect = 2e-04
Identities = 38/153 (24%), Positives = 62/153 (40%), Gaps = 8/153 (5%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N+I L+ +F GL L+M + ++P LR L L F+ + + +
Sbjct: 65 NSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRDLSSLQVFKFSYNKLRVITGQTLQ 124
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR--------GLHN 216
L L + KI + AF GL L L++ N + + F L
Sbjct: 125 GLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGNLLHQLHPSTFSTFTFLDYFRLST 184
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
+ L L +N ++ LPA + + P L NL + N
Sbjct: 185 IRHLYLAENMVRTLPASMLRNMPLLENLYLQGN 217
>BC064986-1|AAH64986.1| 743|Homo sapiens MXRA5 protein protein.
Length = 743
Score = 64.9 bits (151), Expect = 5e-10
Identities = 44/161 (27%), Positives = 77/161 (47%), Gaps = 9/161 (5%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
+E++N+ N I ++ +F GL + +L ++ N I ++P G L N R
Sbjct: 57 VERINLGFNSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRDLSSLQVFKFSYNKLR 116
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE------- 304
+ +T +GL ++ + I +N + F+ L +LR L L+ + + +L P
Sbjct: 117 VITGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGNLLHQLHPSTFSTFTF 176
Query: 305 -EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
++ S +R L LA N +R LP S+LR L +L L N
Sbjct: 177 LDYFRLSTIRHLYLAENMVRTLPASMLRNMPLLENLYLQGN 217
Score = 52.0 bits (119), Expect = 4e-06
Identities = 33/122 (27%), Positives = 58/122 (47%), Gaps = 1/122 (0%)
Query: 250 SFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN 309
+FR L S H++ I + N L E F+ L L L + + I +P+ + +
Sbjct: 42 TFRSLASVPAGIAKHVERINLGFNSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRD 101
Query: 310 -SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
S L+ + N+LRV+ L+G + L L + +N + + P+ F L +L ++GN
Sbjct: 102 LSSLQVFKFSYNKLRVITGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGN 161
Query: 369 EL 370
L
Sbjct: 162 LL 163
Score = 48.0 bits (109), Expect = 6e-05
Identities = 42/156 (26%), Positives = 68/156 (43%), Gaps = 10/156 (6%)
Query: 149 RLNAGRNI--TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANI 206
R+N G N L FA L+ L + +I +PD A L+ L+ N++ I
Sbjct: 59 RINLGFNSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRDLSSLQVFKFSYNKLRVI 118
Query: 207 TAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG---LD 263
T +GL N+ L ++ N+I+ + F L L + N L TF LD
Sbjct: 119 TGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGNLLHQLHPSTFSTFTFLD 178
Query: 264 H-----IQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
+ I+ + ++ N+ TL ++ N+P L L L
Sbjct: 179 YFRLSTIRHLYLAENMVRTLPASMLRNMPLLENLYL 214
Score = 46.4 bits (105), Expect = 2e-04
Identities = 38/153 (24%), Positives = 62/153 (40%), Gaps = 8/153 (5%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N+I L+ +F GL L+M + ++P LR L L F+ + + +
Sbjct: 65 NSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRDLSSLQVFKFSYNKLRVITGQTLQ 124
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR--------GLHN 216
L L + KI + AF GL L L++ N + + F L
Sbjct: 125 GLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGNLLHQLHPSTFSTFTFLDYFRLST 184
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
+ L L +N ++ LPA + + P L NL + N
Sbjct: 185 IRHLYLAENMVRTLPASMLRNMPLLENLYLQGN 217
>BC043165-1|AAH43165.1| 719|Homo sapiens leucine rich repeat and
fibronectin type III domain containing 5 protein.
Length = 719
Score = 64.9 bits (151), Expect = 5e-10
Identities = 41/170 (24%), Positives = 81/170 (47%), Gaps = 2/170 (1%)
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
+L + +N + NI F + ++ L+L++N I + FA L L + N +
Sbjct: 55 ELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKI 114
Query: 255 DSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNS-PLR 313
++ F GL ++ + ++NN + F ++ AL L L +++ +P + + L
Sbjct: 115 TNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLH 174
Query: 314 TLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPE-LFADLRALET 362
TLSL N + +P+ ++T L ++ N + +L P+ LF + L T
Sbjct: 175 TLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLAT 224
Score = 58.0 bits (134), Expect = 5e-08
Identities = 38/134 (28%), Positives = 61/134 (45%)
Query: 98 VKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNIT 157
V + +N I+ + AF L + N+ T + D+ L L H LN +
Sbjct: 78 VDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTL 137
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
+ + F + L+ L+LS + +P DA + L L++ N I NI G F LH +
Sbjct: 138 ISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKM 197
Query: 218 TVLSLNKNRIQALP 231
T L + N++Q LP
Sbjct: 198 TRLDVTSNKLQKLP 211
Score = 53.6 bits (123), Expect = 1e-06
Identities = 35/143 (24%), Positives = 65/143 (45%)
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
FAN L L LS I+ + AF L L L++ N + IT F GL N+ L L
Sbjct: 71 FANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLIL 130
Query: 223 NKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAV 282
N N++ + + F L L + N+ + + + + + + +N+ + +
Sbjct: 131 NNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGT 190
Query: 283 FSNLPALRTLQLDLSSIRELPEE 305
FS+L + L + + +++LP +
Sbjct: 191 FSHLHKMTRLDVTSNKLQKLPPD 213
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/113 (26%), Positives = 56/113 (49%)
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
L L LN+ R + +MF+ L +L L++ ++T++ AF + LE+L++ N
Sbjct: 98 LRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYN 157
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
+ I A + ++ LSL+ N I +P G F+ ++ L + N + L
Sbjct: 158 NLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKL 210
Score = 44.8 bits (101), Expect = 5e-04
Identities = 29/106 (27%), Positives = 52/106 (49%), Gaps = 1/106 (0%)
Query: 267 EIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVL 325
E+++++N +K F+N+ +L L L ++I + P F LR L L N+L +
Sbjct: 55 ELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKI 114
Query: 326 PRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
+ G + L L L+ N + ++ F D+ ALE + N L+
Sbjct: 115 TNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLE 160
Score = 41.9 bits (94), Expect = 0.004
Identities = 30/130 (23%), Positives = 57/130 (43%), Gaps = 1/130 (0%)
Query: 240 RLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI 299
R + L + N + + F + + ++ +S N + F++L LR L L+ + +
Sbjct: 52 RTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRL 111
Query: 300 RELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 358
++ + S S L L L NQL ++ + L L LSYN + + + +
Sbjct: 112 TKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMV 171
Query: 359 ALETFVMDGN 368
+L T +D N
Sbjct: 172 SLHTLSLDHN 181
>BC011846-1|AAH11846.1| 743|Homo sapiens MXRA5 protein protein.
Length = 743
Score = 64.9 bits (151), Expect = 5e-10
Identities = 44/161 (27%), Positives = 77/161 (47%), Gaps = 9/161 (5%)
Query: 193 LEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFR 252
+E++N+ N I ++ +F GL + +L ++ N I ++P G L N R
Sbjct: 57 VERINLGFNSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRDLSSLQVFKFSYNKLR 116
Query: 253 YLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PE------- 304
+ +T +GL ++ + I +N + F+ L +LR L L+ + + +L P
Sbjct: 117 VITGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGNLLHQLHPSTFSTFTF 176
Query: 305 -EFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYN 344
++ S +R L LA N +R LP S+LR L +L L N
Sbjct: 177 LDYFRLSTIRHLYLAENMVRTLPASMLRNMPLLENLYLQGN 217
Score = 52.0 bits (119), Expect = 4e-06
Identities = 33/122 (27%), Positives = 58/122 (47%), Gaps = 1/122 (0%)
Query: 250 SFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISN 309
+FR L S H++ I + N L E F+ L L L + + I +P+ + +
Sbjct: 42 TFRSLASVPAGIAKHVERINLGFNSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRD 101
Query: 310 -SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGN 368
S L+ + N+LRV+ L+G + L L + +N + + P+ F L +L ++GN
Sbjct: 102 LSSLQVFKFSYNKLRVITGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGN 161
Query: 369 EL 370
L
Sbjct: 162 LL 163
Score = 48.0 bits (109), Expect = 6e-05
Identities = 42/156 (26%), Positives = 68/156 (43%), Gaps = 10/156 (6%)
Query: 149 RLNAGRNI--TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANI 206
R+N G N L FA L+ L + +I +PD A L+ L+ N++ I
Sbjct: 59 RINLGFNSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRDLSSLQVFKFSYNKLRVI 118
Query: 207 TAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG---LD 263
T +GL N+ L ++ N+I+ + F L L + N L TF LD
Sbjct: 119 TGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGNLLHQLHPSTFSTFTFLD 178
Query: 264 H-----IQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
+ I+ + ++ N+ TL ++ N+P L L L
Sbjct: 179 YFRLSTIRHLYLAENMVRTLPASMLRNMPLLENLYL 214
Score = 46.4 bits (105), Expect = 2e-04
Identities = 38/153 (24%), Positives = 62/153 (40%), Gaps = 8/153 (5%)
Query: 105 NAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNITLHANMFA 164
N+I L+ +F GL L+M + ++P LR L L F+ + + +
Sbjct: 65 NSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRDLSSLQVFKFSYNKLRVITGQTLQ 124
Query: 165 NTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFR--------GLHN 216
L L + KI + AF GL L L++ N + + F L
Sbjct: 125 GLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGNLLHQLHPSTFSTFTFLDYFRLST 184
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRN 249
+ L L +N ++ LPA + + P L NL + N
Sbjct: 185 IRHLYLAENMVRTLPASMLRNMPLLENLYLQGN 217
>BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 64.9 bits (151), Expect = 5e-10
Identities = 59/204 (28%), Positives = 101/204 (49%), Gaps = 8/204 (3%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
L L +S+ K+ L DD L L L L++ +N++ ++ + A R L N+ L+++ N+++
Sbjct: 84 LTKLIISNNKLQSLTDDLRL-LPALTVLDIHDNQLTSLPS-AIRELENLQKLNVSHNKLK 141
Query: 229 ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPA 288
LP + + L L + N + SE F L +++++ +SNN LT A FS+L +
Sbjct: 142 ILPEEI-TNLRNLKCLYLQHNELTCI-SEGFEQLSNLEDLDLSNN-HLTTVPASFSSLSS 198
Query: 289 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
L L L + ++ LP E L+ L N L +P L G L L L N +
Sbjct: 199 LVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPE-LAGMESLELLYLRRNKLRF 257
Query: 349 LAPELFADLRALETFVMDGNELQV 372
L PE F L+ + N++++
Sbjct: 258 L-PE-FPSCSLLKELHVGENQIEM 279
Score = 51.6 bits (118), Expect = 5e-06
Identities = 38/156 (24%), Positives = 75/156 (48%), Gaps = 3/156 (1%)
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
VT ++ +KN++ +P + + ++ + N ++ E L + + + NN
Sbjct: 427 VTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCV-LQKLTFLDLRNNFLN 485
Query: 277 TLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
+L E + S L L+T+ L + + LPE L T+ ++ NQ+ + ++ L
Sbjct: 486 SLPEEMES-LVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENL 544
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 372
T+L L N + ++ PEL + L T ++DGN +V
Sbjct: 545 TTLDLQNNDLLQIPPEL-GNCVNLRTLLLDGNPFRV 579
Score = 44.0 bits (99), Expect = 0.001
Identities = 35/117 (29%), Positives = 56/117 (47%), Gaps = 3/117 (2%)
Query: 214 LHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L +T L L N + +LP + S RL + + N F+ L +R + ++ I ISNN
Sbjct: 471 LQKLTFLDLRNNFLNSLPEEM-ESLVRLQTINLSFNRFKMLPEVLYR-IFTLETILISNN 528
Query: 274 VPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVL 330
++ + L TL L + + ++P E + LRTL L N RV PR+ +
Sbjct: 529 QVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFRV-PRAAI 584
Score = 37.9 bits (84), Expect = 0.062
Identities = 44/202 (21%), Positives = 101/202 (50%), Gaps = 19/202 (9%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L A + + L+L D K+ +PD+ L L LE+L++ N+I+++ + LH +
Sbjct: 280 LEAEHLKHLNSILVLDLRDNKLKSVPDEIIL-LRSLERLDLSNNDISSLPY-SLGNLH-L 336
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
L+L N ++ + + + + + +YL S+ D + + + +T
Sbjct: 337 KFLALEGNPLRTIRREIISKGTQEV--------LKYLRSKIKD--DGPSQSESATETAMT 386
Query: 278 LKEAVFSNLPALRTLQ-LDLSSIRE--LPEEF---ISNSPLRTLSLARNQLRVLPRSVLR 331
L N+ A+ TL+ LD S + +P+E + ++ + +++ ++NQL +P+ ++
Sbjct: 387 LPSESRVNIHAIITLKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVE 446
Query: 332 GQTQLTSLTLSYNAVAELAPEL 353
+ ++ + LS+N ++ ++ EL
Sbjct: 447 LKEMVSDVDLSFNKLSFISLEL 468
>BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein.
Length = 581
Score = 64.9 bits (151), Expect = 5e-10
Identities = 59/204 (28%), Positives = 101/204 (49%), Gaps = 8/204 (3%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
L L +S+ K+ L DD L L L L++ +N++ ++ + A R L N+ L+++ N+++
Sbjct: 63 LTKLIISNNKLQSLTDDLRL-LPALTVLDIHDNQLTSLPS-AIRELENLQKLNVSHNKLK 120
Query: 229 ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPA 288
LP + + L L + N + SE F L +++++ +SNN LT A FS+L +
Sbjct: 121 ILPEEI-TNLRNLKCLYLQHNELTCI-SEGFEQLSNLEDLDLSNN-HLTTVPASFSSLSS 177
Query: 289 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
L L L + ++ LP E L+ L N L +P L G L L L N +
Sbjct: 178 LVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPE-LAGMESLELLYLRRNKLRF 236
Query: 349 LAPELFADLRALETFVMDGNELQV 372
L PE F L+ + N++++
Sbjct: 237 L-PE-FPSCSLLKELHVGENQIEM 258
Score = 51.6 bits (118), Expect = 5e-06
Identities = 38/156 (24%), Positives = 75/156 (48%), Gaps = 3/156 (1%)
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
VT ++ +KN++ +P + + ++ + N ++ E L + + + NN
Sbjct: 406 VTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCV-LQKLTFLDLRNNFLN 464
Query: 277 TLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
+L E + S L L+T+ L + + LPE L T+ ++ NQ+ + ++ L
Sbjct: 465 SLPEEMES-LVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENL 523
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 372
T+L L N + ++ PEL + L T ++DGN +V
Sbjct: 524 TTLDLQNNDLLQIPPEL-GNCVNLRTLLLDGNPFRV 558
Score = 44.0 bits (99), Expect = 0.001
Identities = 35/117 (29%), Positives = 56/117 (47%), Gaps = 3/117 (2%)
Query: 214 LHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L +T L L N + +LP + S RL + + N F+ L +R + ++ I ISNN
Sbjct: 450 LQKLTFLDLRNNFLNSLPEEM-ESLVRLQTINLSFNRFKMLPEVLYR-IFTLETILISNN 507
Query: 274 VPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVL 330
++ + L TL L + + ++P E + LRTL L N RV PR+ +
Sbjct: 508 QVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFRV-PRAAI 563
Score = 37.9 bits (84), Expect = 0.062
Identities = 44/202 (21%), Positives = 101/202 (50%), Gaps = 19/202 (9%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L A + + L+L D K+ +PD+ L L LE+L++ N+I+++ + LH +
Sbjct: 259 LEAEHLKHLNSILVLDLRDNKLKSVPDEIIL-LRSLERLDLSNNDISSLPY-SLGNLH-L 315
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
L+L N ++ + + + + + +YL S+ D + + + +T
Sbjct: 316 KFLALEGNPLRTIRREIISKGTQEV--------LKYLRSKIKD--DGPSQSESATETAMT 365
Query: 278 LKEAVFSNLPALRTLQ-LDLSSIRE--LPEEF---ISNSPLRTLSLARNQLRVLPRSVLR 331
L N+ A+ TL+ LD S + +P+E + ++ + +++ ++NQL +P+ ++
Sbjct: 366 LPSESRVNIHAIITLKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVE 425
Query: 332 GQTQLTSLTLSYNAVAELAPEL 353
+ ++ + LS+N ++ ++ EL
Sbjct: 426 LKEMVSDVDLSFNKLSFISLEL 447
>AY313607-1|AAP79898.1| 613|Homo sapiens podocan protein protein.
Length = 613
Score = 64.9 bits (151), Expect = 5e-10
Identities = 63/237 (26%), Positives = 105/237 (44%), Gaps = 18/237 (7%)
Query: 146 THFRLNAGRNITLHANMFANTPP-----LKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
T ++L++ + L +N + P L L L I + + + LE L +
Sbjct: 283 TFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHS 342
Query: 201 NEIAN--ITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSET 258
N++ I AF+GL + + L N ++ +P+GL R+ L ++ N + E
Sbjct: 343 NQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGL---PRRVRTLMILHNQITGIGRED 399
Query: 259 FRGLDHIQEIKISNN---VPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTL 315
F ++E+ +S N P ++A F L LR+L L + + LP N + L
Sbjct: 400 FATTYFLEELNLSYNRITSPQVHRDA-FRKLRLLRSLDLSGNRLHMLPPGLPRN--VHVL 456
Query: 316 SLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE--LAPELFADLRALETFVMDGNEL 370
+ RN+L L R L G QL L L+ N + L P + DL L+ + GN+L
Sbjct: 457 KVKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQL 513
Score = 50.4 bits (115), Expect = 1e-05
Identities = 54/214 (25%), Positives = 93/214 (43%), Gaps = 14/214 (6%)
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
F + L YL L++ K+T+ P FL N L ++ N + I F N+ + L
Sbjct: 142 FEHLTNLNYLYLANNKLTLAP--RFLP-NALISVDFAANYLTKIYGLTFGQKPNLRSVYL 198
Query: 223 NKNRIQ--ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKE 280
+ N++ LP +F + + L + N R++ L ++ + NN +
Sbjct: 199 HNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPAL---YKLHLKNNKLEKIPP 255
Query: 281 AVFSNLPALRTLQLDLSSIRELP---EEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLT 337
FS L +LR L L + + + E F S L L L+ N L +P + R L
Sbjct: 256 GAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRS---LV 312
Query: 338 SLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
L L NA+ + + +R+LE ++ N+L+
Sbjct: 313 LLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLR 346
Score = 42.3 bits (95), Expect = 0.003
Identities = 31/106 (29%), Positives = 48/106 (45%), Gaps = 5/106 (4%)
Query: 171 YLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQAL 230
YL + + L A++ L L+ L++ N++ I G L L L N+I A+
Sbjct: 481 YLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLE---YLYLQNNKISAV 537
Query: 231 PAGLFASTPRLLNLTMMRNSFRY--LDSETFRGLDHIQEIKISNNV 274
PA F STP L + + N + FR L H+Q + I N+
Sbjct: 538 PANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGNL 583
Score = 38.7 bits (86), Expect = 0.035
Identities = 42/180 (23%), Positives = 76/180 (42%), Gaps = 11/180 (6%)
Query: 196 LNVWENEIANITAGAFRGLHNVTVLSLNKNRI--QALPAGLFASTPRLLNLTMMRNSFRY 253
L++ N++ I LH + L+L NR+ + LP F L L + N
Sbjct: 101 LSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTL 160
Query: 254 LDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRE--LPEE-FISNS 310
+ F + + + + N + F P LR++ L + + + LP+ F +S
Sbjct: 161 --APRFLP-NALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSS 217
Query: 311 PLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNEL 370
+ L L+ N LR +P+ + L L L N + ++ P F++L +L + N L
Sbjct: 218 NVEVLILSSNFLRHVPKHL---PPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYL 274
Score = 36.7 bits (81), Expect = 0.14
Identities = 35/143 (24%), Positives = 68/143 (47%), Gaps = 6/143 (4%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
+H + F L+ L+LS ++ +LP ++VL+ V NE+A + GA G+ +
Sbjct: 421 VHRDAFRKLRLLRSLDLSGNRLHMLPPGLPRNVHVLK---VKRNELAALARGALAGMAQL 477
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGL-DHIQEIKISNNVPL 276
L L NR+++ G A L +L ++ + L +E GL + ++ + + NN
Sbjct: 478 RELYLTSNRLRSRALGPRAWVD-LAHLQLLDIAGNQL-TEIPEGLPESLEYLYLQNNKIS 535
Query: 277 TLKEAVFSNLPALRTLQLDLSSI 299
+ F + P L+ + L + +
Sbjct: 536 AVPANAFDSTPNLKGIFLRFNKL 558
>AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 64.9 bits (151), Expect = 5e-10
Identities = 59/204 (28%), Positives = 101/204 (49%), Gaps = 8/204 (3%)
Query: 169 LKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQ 228
L L +S+ K+ L DD L L L L++ +N++ ++ + A R L N+ L+++ N+++
Sbjct: 84 LTKLIISNNKLQSLTDDLRL-LPALTVLDIHDNQLTSLPS-AIRELENLQKLNVSHNKLK 141
Query: 229 ALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPA 288
LP + + L L + N + SE F L +++++ +SNN LT A FS+L +
Sbjct: 142 ILPEEI-TNLRNLKCLYLQHNELTCI-SEGFEQLSNLEDLDLSNN-HLTTVPASFSSLSS 198
Query: 289 LRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAE 348
L L L + ++ LP E L+ L N L +P L G L L L N +
Sbjct: 199 LVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPE-LAGMESLELLYLRRNKLRF 257
Query: 349 LAPELFADLRALETFVMDGNELQV 372
L PE F L+ + N++++
Sbjct: 258 L-PE-FPSCSLLKELHVGENQIEM 279
Score = 51.6 bits (118), Expect = 5e-06
Identities = 38/156 (24%), Positives = 75/156 (48%), Gaps = 3/156 (1%)
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
VT ++ +KN++ +P + + ++ + N ++ E L + + + NN
Sbjct: 427 VTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCV-LQKLTFLDLRNNFLN 485
Query: 277 TLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVLRGQTQL 336
+L E + S L L+T+ L + + LPE L T+ ++ NQ+ + ++ L
Sbjct: 486 SLPEEMES-LVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENL 544
Query: 337 TSLTLSYNAVAELAPELFADLRALETFVMDGNELQV 372
T+L L N + ++ PEL + L T ++DGN +V
Sbjct: 545 TTLDLQNNDLLQIPPEL-GNCVNLRTLLLDGNPFRV 579
Score = 44.0 bits (99), Expect = 0.001
Identities = 35/117 (29%), Positives = 56/117 (47%), Gaps = 3/117 (2%)
Query: 214 LHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNN 273
L +T L L N + +LP + S RL + + N F+ L +R + ++ I ISNN
Sbjct: 471 LQKLTFLDLRNNFLNSLPEEM-ESLVRLQTINLSFNRFKMLPEVLYR-IFTLETILISNN 528
Query: 274 VPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNSPLRTLSLARNQLRVLPRSVL 330
++ + L TL L + + ++P E + LRTL L N RV PR+ +
Sbjct: 529 QVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFRV-PRAAI 584
Score = 37.9 bits (84), Expect = 0.062
Identities = 44/202 (21%), Positives = 101/202 (50%), Gaps = 19/202 (9%)
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
L A + + L+L D K+ +PD+ L L LE+L++ N+I+++ + LH +
Sbjct: 280 LEAEHLKHLNSILVLDLRDNKLKSVPDEIIL-LRSLERLDLSNNDISSLPY-SLGNLH-L 336
Query: 218 TVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLT 277
L+L N ++ + + + + + +YL S+ D + + + +T
Sbjct: 337 KFLALEGNPLRTIRREIISKGTQEV--------LKYLRSKIKD--DGPSQSESATETAMT 386
Query: 278 LKEAVFSNLPALRTLQ-LDLSSIRE--LPEEF---ISNSPLRTLSLARNQLRVLPRSVLR 331
L N+ A+ TL+ LD S + +P+E + ++ + +++ ++NQL +P+ ++
Sbjct: 387 LPSESRVNIHAIITLKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVE 446
Query: 332 GQTQLTSLTLSYNAVAELAPEL 353
+ ++ + LS+N ++ ++ EL
Sbjct: 447 LKEMVSDVDLSFNKLSFISLEL 468
>AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein.
Length = 1310
Score = 64.9 bits (151), Expect = 5e-10
Identities = 38/99 (38%), Positives = 56/99 (56%)
Query: 172 LELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALP 231
L LS+ KIT L + +FLGL++LE+L++ N I+ + GAF GL + L L+ NRI L
Sbjct: 61 LLLSNKKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 120
Query: 232 AGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKI 270
+ F PRLL L + N F L F L ++ + +
Sbjct: 121 SETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDL 159
Score = 58.0 bits (134), Expect = 5e-08
Identities = 32/93 (34%), Positives = 46/93 (49%)
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRG 261
+I + G+F GL + L L N I + G F L L + N L SETF+G
Sbjct: 67 KITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQG 126
Query: 262 LDHIQEIKISNNVPLTLKEAVFSNLPALRTLQL 294
L + + IS N+ +L+ VF LPAL+ + L
Sbjct: 127 LPRLLRLNISGNIFSSLQPGVFDELPALKVVDL 159
Score = 47.2 bits (107), Expect = 1e-04
Identities = 32/101 (31%), Positives = 52/101 (51%), Gaps = 1/101 (0%)
Query: 142 LPKLTHFRLNAGRNIT-LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWE 200
LP T L + + IT L F L+ L+L + I+ + AFLGL L++L++
Sbjct: 54 LPNGTVTLLLSNKKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSN 113
Query: 201 NEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRL 241
N I +T+ F+GL + L+++ N +L G+F P L
Sbjct: 114 NRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPAL 154
Score = 34.3 bits (75), Expect = 0.76
Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
Query: 149 RLNAGRNI--TLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANI 206
+L+ NI T+ F LK L+LS+ +I L + F GL L +LN+ N +++
Sbjct: 84 KLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSL 143
Query: 207 TAGAFRGLHNVTVLSL 222
G F L + V+ L
Sbjct: 144 QPGVFDELPALKVVDL 159
Score = 33.9 bits (74), Expect = 1.0
Identities = 26/81 (32%), Positives = 37/81 (45%), Gaps = 3/81 (3%)
Query: 217 VTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPL 276
VT+L NK +I L G F L L + N + F GL ++ + +SNN
Sbjct: 59 VTLLLSNK-KITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIG 117
Query: 277 TLKEAVFSNLPALRTLQLDLS 297
L F LP R L+L++S
Sbjct: 118 CLTSETFQGLP--RLLRLNIS 136
>AK055365-1|BAB70910.1| 719|Homo sapiens protein ( Homo sapiens
cDNA FLJ30803 fis, clone FEBRA2001245, weakly similar to
NAG14. ).
Length = 719
Score = 64.9 bits (151), Expect = 5e-10
Identities = 41/170 (24%), Positives = 81/170 (47%), Gaps = 2/170 (1%)
Query: 195 QLNVWENEIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
+L + +N + NI F + ++ L+L++N I + FA L L + N +
Sbjct: 55 ELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKI 114
Query: 255 DSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIRELPEEFISNS-PLR 313
++ F GL ++ + ++NN + F ++ AL L L +++ +P + + L
Sbjct: 115 TNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLH 174
Query: 314 TLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPE-LFADLRALET 362
TLSL N + +P+ ++T L ++ N + +L P+ LF + L T
Sbjct: 175 TLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLAT 224
Score = 58.0 bits (134), Expect = 5e-08
Identities = 38/134 (28%), Positives = 61/134 (45%)
Query: 98 VKTVVFKNAINPLNADAFKGLGITALMMFNAGAQTTVPVDVLRSLPKLTHFRLNAGRNIT 157
V + +N I+ + AF L + N+ T + D+ L L H LN +
Sbjct: 78 VDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTL 137
Query: 158 LHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNV 217
+ + F + L+ L+LS + +P DA + L L++ N I NI G F LH +
Sbjct: 138 ISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKM 197
Query: 218 TVLSLNKNRIQALP 231
T L + N++Q LP
Sbjct: 198 TRLDVTSNKLQKLP 211
Score = 53.6 bits (123), Expect = 1e-06
Identities = 35/143 (24%), Positives = 65/143 (45%)
Query: 163 FANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWENEIANITAGAFRGLHNVTVLSL 222
FAN L L LS I+ + AF L L L++ N + IT F GL N+ L L
Sbjct: 71 FANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLIL 130
Query: 223 NKNRIQALPAGLFASTPRLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAV 282
N N++ + + F L L + N+ + + + + + + +N+ + +
Sbjct: 131 NNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGT 190
Query: 283 FSNLPALRTLQLDLSSIRELPEE 305
FS+L + L + + +++LP +
Sbjct: 191 FSHLHKMTRLDVTSNKLQKLPPD 213
Score = 48.4 bits (110), Expect = 4e-05
Identities = 30/113 (26%), Positives = 56/113 (49%)
Query: 142 LPKLTHFRLNAGRNITLHANMFANTPPLKYLELSDAKITVLPDDAFLGLNVLEQLNVWEN 201
L L LN+ R + +MF+ L +L L++ ++T++ AF + LE+L++ N
Sbjct: 98 LRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYN 157
Query: 202 EIANITAGAFRGLHNVTVLSLNKNRIQALPAGLFASTPRLLNLTMMRNSFRYL 254
+ I A + ++ LSL+ N I +P G F+ ++ L + N + L
Sbjct: 158 NLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKL 210
Score = 44.8 bits (101), Expect = 5e-04
Identities = 29/106 (27%), Positives = 52/106 (49%), Gaps = 1/106 (0%)
Query: 267 EIKISNNVPLTLKEAVFSNLPALRTLQLDLSSIREL-PEEFISNSPLRTLSLARNQLRVL 325
E+++++N +K F+N+ +L L L ++I + P F LR L L N+L +
Sbjct: 55 ELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKI 114
Query: 326 PRSVLRGQTQLTSLTLSYNAVAELAPELFADLRALETFVMDGNELQ 371
+ G + L L L+ N + ++ F D+ ALE + N L+
Sbjct: 115 TNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLE 160
Score = 41.9 bits (94), Expect = 0.004
Identities = 30/130 (23%), Positives = 57/130 (43%), Gaps = 1/130 (0%)
Query: 240 RLLNLTMMRNSFRYLDSETFRGLDHIQEIKISNNVPLTLKEAVFSNLPALRTLQLDLSSI 299
R + L + N + + F + + ++ +S N + F++L LR L L+ + +
Sbjct: 52 RTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRL 111
Query: 300 RELPEEFISN-SPLRTLSLARNQLRVLPRSVLRGQTQLTSLTLSYNAVAELAPELFADLR 358
++ + S S L L L NQL ++ + L L LSYN + + + +
Sbjct: 112 TKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMV 171
Query: 359 ALETFVMDGN 368
+L T +D N
Sbjct: 172 SLHTLSLDHN 181
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.135 0.392
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 53,527,412
Number of Sequences: 224733
Number of extensions: 2179043
Number of successful extensions: 10111
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 604
Number of HSP's successfully gapped in prelim test: 138
Number of HSP's that attempted gapping in prelim test: 3682
Number of HSP's gapped (non-prelim): 3595
length of query: 395
length of database: 73,234,838
effective HSP length: 91
effective length of query: 304
effective length of database: 52,784,135
effective search space: 16046377040
effective search space used: 16046377040
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 66 (30.7 bits)
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