Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001703-TA|BGIBMGA001703-PA|IPR003599|Immunoglobulin
subtype, IPR003598|Immunoglobulin subtype 2,
IPR007110|Immunoglobulin-like, IPR008957|Fibronectin, type III-like
fold, IPR013151|Immunoglobulin, IPR013098|Immunoglobulin I-set
(500 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AY358328-1|AAQ88694.1| 1115|Homo sapiens BOC protein. 111 5e-24
AY027658-1|AAK14795.1| 1114|Homo sapiens brother of CDO protein. 111 5e-24
AK090455-1|BAC03436.1| 931|Homo sapiens FLJ00376 protein protein. 110 1e-23
U41901-1|AAC50569.1| 338|Homo sapiens LAMP protein. 107 1e-22
L34774-1|AAA36387.1| 345|Homo sapiens opioid-binding cell adhes... 107 1e-22
BX537377-1|CAD97619.1| 338|Homo sapiens hypothetical protein pr... 107 1e-22
BC126251-1|AAI26252.1| 345|Homo sapiens opioid binding protein/... 107 1e-22
BC117254-1|AAI17255.1| 345|Homo sapiens opioid binding protein/... 107 1e-22
BC074773-1|AAH74773.1| 345|Homo sapiens opioid binding protein/... 107 1e-22
BC033803-1|AAH33803.1| 338|Homo sapiens limbic system-associate... 107 1e-22
BC074742-1|AAH74742.1| 344|Homo sapiens opioid binding protein/... 103 1e-21
AY358331-1|AAQ88697.1| 344|Homo sapiens HNT protein. 102 3e-21
AF126426-1|AAF37591.1| 344|Homo sapiens neurotrimin protein. 102 3e-21
BC050716-1|AAH50716.1| 316|Homo sapiens HNT protein protein. 101 4e-21
EF043567-1|ABK34282.1| 355|Homo sapiens neurotrimin variant 3 p... 100 1e-20
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 98 5e-20
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 98 5e-20
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 98 5e-20
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 98 5e-20
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 98 5e-20
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 98 5e-20
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 98 5e-20
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 98 5e-20
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 98 5e-20
BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein. 96 3e-19
AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens ... 92 5e-18
BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein. 91 6e-18
AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, recep... 91 6e-18
AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, recep... 91 6e-18
AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, recep... 91 6e-18
AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, recep... 91 6e-18
AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosin... 91 6e-18
AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein pr... 91 1e-17
AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens ... 91 1e-17
BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell ... 89 3e-17
BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell ... 89 3e-17
AY358132-1|AAQ88499.1| 352|Homo sapiens DMML2433 protein. 89 3e-17
BX538014-1|CAD97961.1| 355|Homo sapiens hypothetical protein pr... 89 3e-17
BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein. 89 3e-17
AL645724-1|CAI21858.1| 354|Homo sapiens neuronal growth regulat... 89 3e-17
AL627317-1|CAH72391.1| 354|Homo sapiens neuronal growth regulat... 89 3e-17
AL359821-1|CAH70913.1| 354|Homo sapiens neuronal growth regulat... 89 3e-17
AL356600-1|CAI23492.1| 354|Homo sapiens neuronal growth regulat... 89 3e-17
AL354949-1|CAI16869.1| 354|Homo sapiens neuronal growth regulat... 89 3e-17
AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein. 89 3e-17
AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein. 89 3e-17
AL360004-4|CAI16954.2| 746|Homo sapiens novel protein similar t... 89 4e-17
AK092307-1|BAC03858.1| 354|Homo sapiens protein ( Homo sapiens ... 88 8e-17
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 88 8e-17
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 87 2e-16
AK128160-1|BAC87305.1| 632|Homo sapiens protein ( Homo sapiens ... 87 2e-16
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 85 4e-16
AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein L... 85 4e-16
X16841-1|CAA34739.1| 761|Homo sapiens protein ( Human mRNA for ... 85 5e-16
BC036771-1|AAH36771.1| 226|Homo sapiens NEGR1 protein protein. 85 5e-16
AL627317-2|CAH72392.1| 226|Homo sapiens neuronal growth regulat... 85 5e-16
AL359821-2|CAH70914.1| 226|Homo sapiens neuronal growth regulat... 85 5e-16
AL356600-2|CAI23493.1| 226|Homo sapiens neuronal growth regulat... 85 5e-16
AL354949-2|CAI16870.1| 226|Homo sapiens neuronal growth regulat... 85 5e-16
AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein L... 85 5e-16
X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein. 83 3e-15
S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein. 83 3e-15
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly... 83 3e-15
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog... 83 3e-15
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog... 83 3e-15
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog... 83 3e-15
AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein. 83 3e-15
AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion mo... 83 3e-15
U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion mole... 82 4e-15
AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-speci... 82 4e-15
BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein. 81 9e-15
AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein. 81 1e-14
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h... 79 4e-14
U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion prot... 79 4e-14
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 79 5e-14
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 79 5e-14
BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion mo... 79 5e-14
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 79 5e-14
AF478693-1|AAM77220.1| 955|Homo sapiens glycosyl-phosphatidyl-i... 79 5e-14
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 79 5e-14
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 78 6e-14
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 78 6e-14
AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein. 78 6e-14
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 78 6e-14
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 78 6e-14
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 78 6e-14
AK074921-1|BAC11295.1| 697|Homo sapiens protein ( Homo sapiens ... 78 6e-14
AY369208-1|AAQ73312.1| 956|Homo sapiens MAM domain-containing g... 78 8e-14
X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor ... 77 1e-13
X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal glycopro... 77 1e-13
BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal) pr... 77 1e-13
AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal) pr... 77 1e-13
AL049553-2|CAI20461.1| 957|Homo sapiens MAM domain containing g... 77 1e-13
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 76 3e-13
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 76 3e-13
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 76 3e-13
AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein... 76 3e-13
AL117666-1|CAB56036.1| 483|Homo sapiens hypothetical protein pr... 76 3e-13
AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens ... 76 3e-13
AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein. 75 4e-13
AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens ... 75 6e-13
BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein. 75 8e-13
BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein. 75 8e-13
BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein. 75 8e-13
Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein. 74 1e-12
U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein. 74 1e-12
U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor p... 74 1e-12
U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor p... 74 1e-12
AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal ... 74 1e-12
AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal... 74 1e-12
AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal ... 74 1e-12
AJ314900-1|CAC85747.1| 551|Homo sapiens obscurin protein. 74 1e-12
AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein. 74 1e-12
AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein. 74 1e-12
U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein. 73 2e-12
BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1 (chi... 73 2e-12
BC047244-1|AAH47244.1| 858|Homo sapiens neural cell adhesion mo... 73 2e-12
BC014205-1|AAH14205.2| 601|Homo sapiens NCAM1 protein protein. 73 2e-12
AY358125-1|AAQ88492.1| 937|Homo sapiens MAM-domain protein prot... 73 2e-12
AF190637-1|AAG17141.1| 1241|Homo sapiens nephrin protein. 73 2e-12
AF035835-1|AAC39687.1| 1241|Homo sapiens nephrin protein. 73 2e-12
X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein. 73 2e-12
M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorecta... 73 2e-12
AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein. 73 3e-12
AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein. 73 3e-12
BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein. 71 7e-12
BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein. 71 7e-12
BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein. 71 7e-12
AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein. 71 7e-12
X59350-1|CAA42006.1| 847|Homo sapiens B Cell membrane protein C... 71 1e-11
U62631-1|AAB06448.1| 847|Homo sapiens B-cell receptor CD22-B is... 71 1e-11
EF064756-1|ABK41939.1| 847|Homo sapiens CD22 molecule protein. 71 1e-11
BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein pr... 71 1e-11
BC109306-1|AAI09307.1| 675|Homo sapiens CD22 protein protein. 71 1e-11
AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein. 71 1e-11
AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related c... 71 1e-11
AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related c... 71 1e-11
AB253795-1|BAF32758.1| 847|Homo sapiens CD22 antigen protein. 71 1e-11
AB253794-1|BAF32757.1| 847|Homo sapiens CD22 antigen protein. 71 1e-11
AB253793-1|BAF32756.1| 847|Homo sapiens CD22 antigen protein. 71 1e-11
S61375-1|AAC18956.1| 662|Homo sapiens CD22 protein protein. 71 1e-11
BC104918-1|AAI04919.1| 1208|Homo sapiens CHL1 protein protein. 70 2e-11
AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhe... 70 2e-11
AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhe... 70 2e-11
AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell adhe... 70 2e-11
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 70 2e-11
AF002246-1|AAB60937.1| 1224|Homo sapiens neural cell adhesion mo... 70 2e-11
AB209329-1|BAD92566.1| 1210|Homo sapiens Neural cell adhesion mo... 70 2e-11
AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein. 70 2e-11
AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog (ch... 69 4e-11
AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog (ch... 69 4e-11
AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant... 69 4e-11
AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein. 69 4e-11
BC036569-1|AAH36569.1| 627|Homo sapiens CNTN1 protein protein. 69 5e-11
AK097578-1|BAC05109.1| 600|Homo sapiens protein ( Homo sapiens ... 69 5e-11
AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhe... 69 5e-11
U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor pr... 68 7e-11
U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4 ... 68 7e-11
EF063638-1|ABO42328.1| 1896|Homo sapiens obscurin-like 1 isoform... 68 7e-11
EF063637-1|ABO42327.1| 1544|Homo sapiens obscurin-like 1 isoform... 68 7e-11
BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine k... 68 7e-11
BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein. 68 7e-11
AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine k... 68 7e-11
AF531872-1|AAN04866.1| 816|Homo sapiens transmembrane receptor ... 68 7e-11
AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor ... 68 7e-11
AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase... 68 7e-11
AB209350-1|BAD92587.1| 773|Homo sapiens PTK7 protein tyrosine k... 68 7e-11
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 68 9e-11
BC045734-1|AAH45734.1| 442|Homo sapiens IGSF10 protein protein. 67 1e-10
BC031063-1|AAH31063.1| 602|Homo sapiens IGSF10 protein protein. 67 1e-10
AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down synd... 67 1e-10
AK098838-1|BAC05429.1| 399|Homo sapiens protein ( Homo sapiens ... 67 1e-10
AK093069-1|BAC04042.1| 650|Homo sapiens protein ( Homo sapiens ... 67 1e-10
AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell adhe... 67 1e-10
AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell adhe... 67 1e-10
AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell adhe... 67 1e-10
AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell adhe... 67 1e-10
AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell adhe... 67 1e-10
DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein. 67 2e-10
DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein. 67 2e-10
BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein. 67 2e-10
AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein. 67 2e-10
AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecul... 67 2e-10
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly... 66 2e-10
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 66 2e-10
AY328482-1|AAP97010.1| 571|Homo sapiens MAM domain containing 1... 66 2e-10
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 66 3e-10
AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kina... 66 3e-10
AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1... 66 4e-10
EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein. 65 5e-10
AY358128-1|AAQ88495.1| 717|Homo sapiens IGSF9 protein. 65 5e-10
X90568-1|CAA62188.1|26926|Homo sapiens titin protein. 65 6e-10
U55258-1|AAC50765.1| 1299|Homo sapiens hBRAVO/Nr-CAM precursor p... 65 6e-10
AK131073-1|BAC85123.1| 659|Homo sapiens FLJ00259 protein protein. 65 6e-10
AF109907-3|AAC97963.1| 1235|Homo sapiens hypothetical protein pr... 65 6e-10
BC141884-1|AAI41885.1| 1688|Homo sapiens SIGLEC1 protein protein. 64 8e-10
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly... 64 8e-10
AL109804-4|CAC17543.1| 1709|Homo sapiens sialic acid binding Ig-... 64 8e-10
AL109804-3|CAC17542.1| 462|Homo sapiens sialic acid binding Ig-... 64 8e-10
AK024462-1|BAB15752.1| 977|Homo sapiens FLJ00055 protein protein. 64 8e-10
AF363368-1|AAM60750.1| 388|Homo sapiens TSLC1-like 2 protein. 64 8e-10
AF230073-1|AAK00757.1| 1709|Homo sapiens sialoadhesin protein. 64 8e-10
Z29373-1|CAA82564.1| 1257|Homo sapiens neural cell adhesion mole... 64 1e-09
M77640-1|AAC14352.1| 1257|Homo sapiens L1 cell adhesion molecule... 64 1e-09
M74387-1|AAA59476.1| 1253|Homo sapiens cell adhesion molecule L1... 64 1e-09
DQ173642-2|ABC25979.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173641-2|ABC25974.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173640-2|ABC25969.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173639-2|ABC25964.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173638-2|ABC25959.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173637-2|ABC25954.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173636-2|ABC25949.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173635-2|ABC25944.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173634-2|ABC25939.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173633-2|ABC25934.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173632-2|ABC25929.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173631-2|ABC25924.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173630-2|ABC25919.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173629-2|ABC25914.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173628-2|ABC25909.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173627-2|ABC25904.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173626-2|ABC25899.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173625-2|ABC25894.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173624-2|ABC25889.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173623-2|ABC25884.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173622-2|ABC25879.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173621-2|ABC25874.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173620-2|ABC25869.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173619-2|ABC25864.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173618-2|ABC25859.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173617-2|ABC25854.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173616-2|ABC25849.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173615-2|ABC25844.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173614-2|ABC25839.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173613-2|ABC25834.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173612-2|ABC25829.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173611-2|ABC25824.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173610-2|ABC25819.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173609-2|ABC25814.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173608-2|ABC25809.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173607-2|ABC25804.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173606-2|ABC25799.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173605-2|ABC25794.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173604-2|ABC25789.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173603-2|ABC25784.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173602-2|ABC25779.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173601-2|ABC25774.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173600-2|ABC25769.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173599-2|ABC25764.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173598-2|ABC25759.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173597-2|ABC25755.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173596-2|ABC25750.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173595-2|ABC25745.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173594-2|ABC25740.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173593-2|ABC25735.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173592-2|ABC25730.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
DQ173589-1|ABB58724.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
BC126229-1|AAI26230.1| 1257|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY358330-1|AAQ88696.1| 477|Homo sapiens papilin protein. 64 1e-09
AY167726-1|AAO17629.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167725-1|AAO17628.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167724-1|AAO17627.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167723-1|AAO17626.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167722-1|AAO17625.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167721-1|AAO17624.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167720-1|AAO17623.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167719-1|AAO17622.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167718-1|AAO17621.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167717-1|AAO17620.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167716-1|AAO17619.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167715-1|AAO17618.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167714-1|AAO17617.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167713-1|AAO17616.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167712-1|AAO17615.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167711-1|AAO17614.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167710-1|AAO17613.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167709-1|AAO17612.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167708-1|AAO17611.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167707-1|AAO17610.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167706-1|AAO17609.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167705-1|AAO17608.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167704-1|AAO17607.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167703-1|AAO17606.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167702-1|AAO17605.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167701-1|AAO17604.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167700-1|AAO17603.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167699-1|AAO17602.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167698-1|AAO17601.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167697-1|AAO17600.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167696-1|AAO17599.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167695-1|AAO17598.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167694-1|AAO17597.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167693-1|AAO17596.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167692-1|AAO17595.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167691-1|AAO17594.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167690-1|AAO17593.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167689-1|AAO17592.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167688-1|AAO17591.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167687-1|AAO17590.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167686-1|AAO17589.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167685-1|AAO17588.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167684-1|AAO17587.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167683-1|AAO17586.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167682-1|AAO17585.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167681-1|AAO17584.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AY167680-1|AAO17583.1| 534|Homo sapiens L1 cell adhesion molecu... 64 1e-09
AK024479-1|BAB15769.1| 462|Homo sapiens FLJ00073 protein protein. 64 1e-09
AK024459-1|BAB15749.1| 462|Homo sapiens FLJ00051 protein protein. 64 1e-09
AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kina... 64 1e-09
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 64 1e-09
AC005525-1|AAC32740.1| 381|Homo sapiens F22162_1 protein. 64 1e-09
AB102653-1|BAC81122.1| 1255|Homo sapiens L1 cell adhesion molecu... 64 1e-09
M29273-1|AAA59545.1| 626|Homo sapiens MAG protein. 64 1e-09
BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein. 64 1e-09
BC093045-1|AAH93045.1| 582|Homo sapiens myelin associated glyco... 64 1e-09
BC053347-1|AAH53347.1| 626|Homo sapiens myelin associated glyco... 64 1e-09
AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle prefere... 64 1e-09
AL513485-5|CAI14605.1| 1179|Homo sapiens immunoglobulin superfam... 64 1e-09
AK223562-1|BAD97282.1| 626|Homo sapiens myelin associated glyco... 64 1e-09
AK222649-1|BAD96369.1| 626|Homo sapiens myelin associated glyco... 64 1e-09
AJ277892-5|CAD12459.1| 2154|Homo sapiens Titin Novex-1 Isoform p... 64 1e-09
AJ277892-4|CAD12458.1| 1294|Homo sapiens Titin Novex-2 Isoform p... 64 1e-09
AJ277892-3|CAD12457.1| 5604|Homo sapiens Novex-3 Titin Isoform p... 64 1e-09
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein. 64 1e-09
AC023270-1|AAX88844.1| 5604|Homo sapiens unknown protein. 64 1e-09
AC002132-1|AAB58805.1| 626|Homo sapiens MAG protein. 64 1e-09
AB209170-1|BAD92407.1| 661|Homo sapiens myelin associated glyco... 64 1e-09
AB037776-1|BAA92593.1| 1189|Homo sapiens KIAA1355 protein protein. 64 1e-09
BC070170-1|AAH70170.1| 637|Homo sapiens TTN protein protein. 63 2e-09
BC058824-1|AAH58824.1| 558|Homo sapiens TTN protein protein. 63 2e-09
BC013396-1|AAH13396.1| 305|Homo sapiens TTN protein protein. 63 2e-09
EF064730-1|ABK41913.1| 977|Homo sapiens Fc receptor-like 5 prot... 63 3e-09
BC101069-1|AAI01070.1| 977|Homo sapiens Fc receptor-like 5 prot... 63 3e-09
BC101067-1|AAI01068.1| 977|Homo sapiens Fc receptor-like 5 prot... 63 3e-09
BC101066-1|AAI01067.1| 977|Homo sapiens Fc receptor-like 5 prot... 63 3e-09
AL513328-3|CAI17351.1| 116|Homo sapiens muscle, skeletal, recep... 63 3e-09
AL353899-3|CAH71429.1| 592|Homo sapiens Fc receptor-like 5 prot... 63 3e-09
AL353899-1|CAH71427.1| 977|Homo sapiens Fc receptor-like 5 prot... 63 3e-09
AL135929-6|CAI22865.1| 592|Homo sapiens Fc receptor-like 5 prot... 63 3e-09
AL135929-4|CAI22863.1| 977|Homo sapiens Fc receptor-like 5 prot... 63 3e-09
AK090423-1|BAC03404.1| 437|Homo sapiens FLJ00333 protein protein. 63 3e-09
AJ314898-1|CAC85746.1| 646|Homo sapiens obscurin protein. 63 3e-09
AF397453-1|AAK93971.1| 977|Homo sapiens Fc receptor-like protei... 63 3e-09
AF343664-1|AAK31327.1| 977|Homo sapiens immunoglobulin superfam... 63 3e-09
Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -... 62 3e-09
BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine phosph... 62 3e-09
BC036502-1|AAH36502.1| 847|Homo sapiens follistatin-like 5 prot... 62 3e-09
AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine phosp... 62 3e-09
AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine phosph... 62 3e-09
AF343663-1|AAK31326.1| 592|Homo sapiens immunoglobulin superfam... 62 3e-09
AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein. 62 3e-09
AB177856-1|BAD66834.1| 1484|Homo sapiens LAR splice variant 1 pr... 62 3e-09
AB033089-1|BAA86577.1| 850|Homo sapiens KIAA1263 protein protein. 62 3e-09
BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein. 62 4e-09
AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog (ch... 62 4e-09
AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog (ch... 62 4e-09
AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog (ch... 62 4e-09
AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog (ch... 62 4e-09
AL391822-2|CAI14657.1| 619|Homo sapiens neurofascin homolog (ch... 62 4e-09
BC007201-1|AAH07201.1| 1044|Homo sapiens OBSL1 protein protein. 62 6e-09
AL049946-1|CAB43220.1| 584|Homo sapiens hypothetical protein pr... 62 6e-09
AF369794-1|AAK50059.2| 977|Homo sapiens B cell crosslinked IgM-... 62 6e-09
X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase... 61 8e-09
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 61 8e-09
BC030141-1|AAH30141.1| 1163|Homo sapiens immunoglobulin superfam... 61 1e-08
BC024300-1|AAH24300.1| 605|Homo sapiens FSTL4 protein protein. 61 1e-08
BC012102-1|AAH12102.1| 347|Homo sapiens PTPRF protein protein. 61 1e-08
BC008124-1|AAH08124.2| 294|Homo sapiens NFASC protein protein. 61 1e-08
AL583862-13|CAI14896.1| 347|Homo sapiens protein tyrosine phosp... 61 1e-08
AL513485-4|CAI14606.1| 1163|Homo sapiens immunoglobulin superfam... 61 1e-08
AL137695-1|CAB70877.1| 773|Homo sapiens hypothetical protein pr... 61 1e-08
AB028984-1|BAA83013.1| 693|Homo sapiens KIAA1061 protein protein. 61 1e-08
AK222680-1|BAD96400.1| 626|Homo sapiens myelin associated glyco... 60 1e-08
AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein. 60 1e-08
BC098583-1|AAH98583.1| 1287|Homo sapiens Cdon homolog (mouse) pr... 60 2e-08
BC026119-1|AAH26119.1| 697|Homo sapiens contactin 4 protein. 60 2e-08
AL583862-11|CAM12884.1| 262|Homo sapiens protein tyrosine phosp... 60 2e-08
DQ234351-1|ABB29980.1| 262|Homo sapiens protein tyrosine phosph... 59 3e-08
BC114435-1|AAI14436.1| 1264|Homo sapiens Cdon homolog (mouse) pr... 59 3e-08
AF132811-1|AAF69029.1| 442|Homo sapiens nectin-like protein 2 p... 59 3e-08
AF004841-1|AAC34901.2| 1264|Homo sapiens CDO protein. 59 3e-08
X83425-1|CAA58449.1| 628|Homo sapiens Lutheran blood group glyc... 59 4e-08
X80026-1|CAA56327.1| 588|Homo sapiens B-CAM protein. 59 4e-08
CR457157-1|CAG33438.1| 442|Homo sapiens IGSF4 protein. 59 4e-08
BC125103-1|AAI25104.1| 414|Homo sapiens CADM1 protein protein. 59 4e-08
BC125102-1|AAI25103.1| 415|Homo sapiens CADM1 protein protein. 59 4e-08
BC050450-1|AAH50450.1| 628|Homo sapiens basal cell adhesion mol... 59 4e-08
BC048416-1|AAH48416.1| 353|Homo sapiens PTPRF protein protein. 59 4e-08
BC047021-1|AAH47021.1| 387|Homo sapiens CADM1 protein protein. 59 4e-08
AY845133-1|AAV88096.1| 628|Homo sapiens Lutheran blood group (A... 59 4e-08
AY358742-1|AAQ89102.1| 708|Homo sapiens LRMR5827 protein. 59 4e-08
AY358334-1|AAQ88700.1| 440|Homo sapiens IGSF4 protein. 59 4e-08
AL834247-1|CAD38923.2| 1391|Homo sapiens hypothetical protein pr... 59 4e-08
AL832002-1|CAD89906.1| 1320|Homo sapiens hypothetical protein pr... 59 4e-08
AL583862-12|CAI14897.1| 353|Homo sapiens protein tyrosine phosp... 59 4e-08
AL512429-2|CAH73748.1| 1320|Homo sapiens sarcomeric protein myop... 59 4e-08
AK075502-1|BAC11657.1| 443|Homo sapiens protein ( Homo sapiens ... 59 4e-08
AK027343-1|BAB55048.1| 507|Homo sapiens .117). protein. 59 4e-08
AF328296-1|AAK50625.1| 1320|Homo sapiens myopalladin protein. 59 4e-08
AB094146-1|BAC66178.1| 333|Homo sapiens secretory isoform of TS... 59 4e-08
AB017563-1|BAA75822.1| 442|Homo sapiens IGSF4 protein. 59 4e-08
BC030132-1|AAH30132.2| 812|Homo sapiens ICAM5 protein protein. 58 5e-08
BC026338-1|AAH26338.1| 924|Homo sapiens intercellular adhesion ... 58 5e-08
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 58 5e-08
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 58 5e-08
AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein. 58 5e-08
AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor ... 58 5e-08
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 58 5e-08
BC101801-1|AAI01802.1| 778|Homo sapiens kin of IRRE like 3 prot... 58 7e-08
BC101775-1|AAI01776.1| 778|Homo sapiens kin of IRRE like 3 (Dro... 58 7e-08
AY358743-1|AAQ89103.1| 600|Homo sapiens NEPH2 protein. 58 7e-08
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot... 58 7e-08
AF480410-1|AAN73042.1| 778|Homo sapiens NPEH2 protein. 58 7e-08
AB058770-1|BAB47496.1| 779|Homo sapiens KIAA1867 protein protein. 58 7e-08
X59847-1|CAA42508.1| 1257|Homo sapiens Neural cell adhesion mole... 58 9e-08
BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein. 58 9e-08
BC082969-1|AAH82969.1| 446|Homo sapiens KIRREL protein protein. 58 9e-08
BC067097-1|AAH67097.1| 446|Homo sapiens KIRREL protein protein. 58 9e-08
BC051356-1|AAH51356.1| 446|Homo sapiens KIRREL protein protein. 58 9e-08
AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens ... 58 9e-08
AK074556-1|BAC11057.1| 789|Homo sapiens protein ( Homo sapiens ... 58 9e-08
BC029119-1|AAH29119.1| 364|Homo sapiens NCAM1 protein protein. 57 1e-07
BC014276-1|AAH14276.2| 417|Homo sapiens LRIG1 protein protein. 57 1e-07
AL353899-2|CAH71428.1| 759|Homo sapiens Fc receptor-like 5 prot... 57 1e-07
AL135929-5|CAI22864.1| 759|Homo sapiens Fc receptor-like 5 prot... 57 1e-07
AK023854-1|BAB14704.1| 442|Homo sapiens .117). protein. 57 2e-07
AF343662-1|AAK31325.1| 759|Homo sapiens immunoglobulin superfam... 57 2e-07
U72671-1|AAC50959.1| 924|Homo sapiens telencephalin precursor p... 56 2e-07
BC064925-1|AAH64925.1| 688|Homo sapiens KIRREL2 protein protein. 56 2e-07
AF082802-1|AAC97931.1| 924|Homo sapiens telencephalin protein. 56 2e-07
AB014557-1|BAA31632.2| 1237|Homo sapiens KIAA0657 protein protein. 56 2e-07
X69490-1|CAA49245.1| 4650|Homo sapiens titin protein. 56 3e-07
X64697-1|CAA45938.1| 3100|Homo sapiens titin protein. 56 3e-07
AL591423-1|CAM13086.1| 1263|Homo sapiens chromosome 9 open readi... 56 4e-07
AL353895-2|CAM20931.1| 1263|Homo sapiens chromosome 9 open readi... 56 4e-07
AL158150-4|CAM14352.1| 1263|Homo sapiens chromosome 9 open readi... 56 4e-07
AF416903-1|AAL13292.1| 740|Homo sapiens SH2 domain-containing p... 56 4e-07
BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine phosph... 55 5e-07
AF531870-1|AAN04864.1| 940|Homo sapiens transmembrane receptor ... 55 5e-07
AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor ... 55 5e-07
AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine phosph... 55 5e-07
BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein. 55 7e-07
AY305302-1|AAP72167.1| 583|Homo sapiens kin of irregular chiasm... 55 7e-07
AY305301-1|AAP72166.1| 633|Homo sapiens kin of irregular chiasm... 55 7e-07
AL356276-1|CAH73052.1| 366|Homo sapiens Fc receptor-like 1 prot... 55 7e-07
AL139409-1|CAH70232.1| 366|Homo sapiens Fc receptor-like 1 prot... 55 7e-07
AK096690-1|BAC04842.1| 366|Homo sapiens protein ( Homo sapiens ... 55 7e-07
EF064732-1|ABK41915.1| 734|Homo sapiens Fc receptor-like 3 prot... 54 9e-07
BC028933-1|AAH28933.1| 742|Homo sapiens FCRL3 protein protein. 54 9e-07
AY043466-1|AAK91779.1| 734|Homo sapiens Fc receptor-like protei... 54 9e-07
AL356276-6|CAH73058.1| 734|Homo sapiens Fc receptor-like 3 prot... 54 9e-07
AL356276-5|CAH73056.1| 742|Homo sapiens Fc receptor-like 3 prot... 54 9e-07
AL356276-4|CAH73055.1| 707|Homo sapiens Fc receptor-like 3 prot... 54 9e-07
AK223266-1|BAD96986.1| 739|Homo sapiens vascular cell adhesion ... 54 9e-07
AF459027-1|AAL59390.1| 734|Homo sapiens immunoglobulin superfam... 54 9e-07
AF416901-1|AAL13290.1| 734|Homo sapiens SH2 domain-containing p... 54 9e-07
AY358153-1|AAQ88520.1| 262|Homo sapiens AWKS9372 protein. 54 1e-06
AK172838-1|BAD18803.1| 218|Homo sapiens protein ( Homo sapiens ... 54 1e-06
AJ314901-1|CAC85749.1| 183|Homo sapiens obscurin protein. 54 1e-06
X53051-1|CAA37218.1| 739|Homo sapiens precursor peptide protein. 54 2e-06
M73255-1|AAA61270.1| 739|Homo sapiens vascular cell adhesion mo... 54 2e-06
M60335-1|AAA61269.1| 739|Homo sapiens vascular cell adhesion mo... 54 2e-06
BC085003-1|AAH85003.1| 739|Homo sapiens vascular cell adhesion ... 54 2e-06
BC068490-1|AAH68490.2| 739|Homo sapiens vascular cell adhesion ... 54 2e-06
BC017276-1|AAH17276.3| 739|Homo sapiens vascular cell adhesion ... 54 2e-06
AL590103-6|CAI12129.1| 188|Homo sapiens heparan sulfate proteog... 54 2e-06
AF536818-1|AAM96190.1| 739|Homo sapiens vascular cell adhesion ... 54 2e-06
AY302131-1|AAP59845.1| 593|Homo sapiens NEPH1 protein protein. 53 2e-06
AL139010-2|CAH73882.1| 593|Homo sapiens kin of IRRE like (Droso... 53 2e-06
AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine phosph... 53 2e-06
X52785-1|CAA36988.1| 647|Homo sapiens CD22 antigen protein. 53 3e-06
U62631-2|AAB06449.1| 670|Homo sapiens B-cell receptor CD22-A is... 53 3e-06
BC014671-1|AAH14671.1| 331|Homo sapiens MYOM3 protein protein. 53 3e-06
AL591178-3|CAH72090.1| 1437|Homo sapiens myomesin family, member... 53 3e-06
AL591178-2|CAH72089.1| 330|Homo sapiens myomesin family, member... 53 3e-06
AK128233-1|BAC87343.1| 1172|Homo sapiens protein ( Homo sapiens ... 53 3e-06
AF202063-1|AAF27432.1| 762|Homo sapiens fibroblast growth facto... 53 3e-06
AC005338-1|AAC27825.1| 475|Homo sapiens PTPsigma, partial CDS p... 53 3e-06
U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein. 52 5e-06
U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein. 52 5e-06
AJ314903-1|CAC85750.1| 542|Homo sapiens obscurin protein. 52 5e-06
AF416902-1|AAL13291.1| 639|Homo sapiens SH2 domain-containing p... 52 5e-06
AF040991-1|AAC39576.1| 285|Homo sapiens roundabout 2 protein. 52 6e-06
AC079227-1|AAY40948.1| 274|Homo sapiens unknown protein. 52 6e-06
BX538319-1|CAD98093.1| 1290|Homo sapiens hypothetical protein pr... 51 8e-06
BC131822-1|AAI31823.1| 1356|Homo sapiens kinase insert domain re... 51 8e-06
BC005376-1|AAH05376.1| 498|Homo sapiens myotilin protein. 51 8e-06
AF144477-1|AAD44754.1| 498|Homo sapiens myotilin protein. 51 8e-06
AF133820-1|AAD29051.2| 498|Homo sapiens titin-like protein prot... 51 8e-06
AB209901-1|BAD93138.1| 1451|Homo sapiens kinase insert domain re... 51 8e-06
X61656-1|CAA43837.1| 1354|Homo sapiens membrane protein protein. 51 1e-05
L38929-1|AAC41749.1| 1912|Homo sapiens protein tyrosine phosphat... 51 1e-05
L04947-1|AAA59459.1| 1354|Homo sapiens receptor tyrosine kinase ... 51 1e-05
EF064734-1|ABK41917.1| 429|Homo sapiens Fc receptor-like 1 prot... 51 1e-05
BC106715-1|AAI06716.1| 1505|Homo sapiens PTPRD protein protein. 51 1e-05
BC106714-1|AAI06715.1| 1506|Homo sapiens PTPRD protein protein. 51 1e-05
BC033690-1|AAH33690.1| 429|Homo sapiens Fc receptor-like 1 prot... 51 1e-05
AY043464-1|AAK91777.1| 429|Homo sapiens Fc receptor-like protei... 51 1e-05
AL590397-1|CAH73128.2| 1912|Homo sapiens protein tyrosine phosph... 51 1e-05
AL583805-2|CAH70443.2| 1912|Homo sapiens protein tyrosine phosph... 51 1e-05
>AY358328-1|AAQ88694.1| 1115|Homo sapiens BOC protein.
Length = 1115
Score = 111 bits (267), Expect = 5e-24
Identities = 70/204 (34%), Positives = 101/204 (49%), Gaps = 21/204 (10%)
Query: 158 RVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSR 217
RV R ++ PP E + + +G + +LEC A+G P P VTW + D SS
Sbjct: 220 RVRRSTAEAARIIYPP------EAQTIIVTKGQSLILECVASGIPPPRVTWAK--DGSSV 271
Query: 218 LGEGP------QLQLSRLERHHGGVYACTVDNGVGPP--VVTEFQLQVLYPPEITVERSW 269
G L + G Y C DNGVG P V + +QV PPE+T+E S
Sbjct: 272 TGYNKTRFLLSNLLIDTTSEEDSGTYRCMADNGVGQPGAAVILYNVQVFEPPEVTMELSQ 331
Query: 270 VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFG 329
+ G A+L C V +PP V W +N+ PL +S+R+ +S R L + + PED G
Sbjct: 332 LVIPWGQSAKLTCEVRGNPPPSVLWLRNAVPLISSQRLRLSRR----ALRVLSMGPEDEG 387
Query: 330 NYSCVADNSLGRARRHVEV-SGRP 352
Y C+A+N +G A V++ + RP
Sbjct: 388 VYQCMAENEVGSAHAVVQLRTSRP 411
Score = 34.7 bits (76), Expect = 0.76
Identities = 47/175 (26%), Positives = 64/175 (36%), Gaps = 16/175 (9%)
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWH----RLNDSSSRLG---EGPQLQ 225
P V P + + GG +L C P VTW LN S LG L
Sbjct: 36 PQVTVQPAS--TVQKPGGTVILGC-VVEPPRMNVTWRLNGKELNGSDDALGVLITHGTLV 92
Query: 226 LSRLERHHGGVYACT--VDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCT 283
++ L H G Y C + G V L L ++ V+ + EG A + C
Sbjct: 93 ITALNNHTVGRYQCVARMPAGAVASVPATVTLANLQDFKLDVQHV-IEVDEGNTAVIACH 151
Query: 284 VL-ADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADN 337
+ + P A+V + L AS + N L I + ED G Y C A N
Sbjct: 152 LPESHPKAQVRYSVKQEWLEASRGNYLIMPSGN--LQIVNASQEDEGMYKCAAYN 204
>AY027658-1|AAK14795.1| 1114|Homo sapiens brother of CDO protein.
Length = 1114
Score = 111 bits (267), Expect = 5e-24
Identities = 70/204 (34%), Positives = 101/204 (49%), Gaps = 21/204 (10%)
Query: 158 RVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSR 217
RV R ++ PP E + + +G + +LEC A+G P P VTW + D SS
Sbjct: 220 RVRRSTAEAARIIYPP------EAQTIIVTKGQSLILECVASGIPPPRVTWAK--DGSSV 271
Query: 218 LGEGP------QLQLSRLERHHGGVYACTVDNGVGPP--VVTEFQLQVLYPPEITVERSW 269
G L + G Y C DNGVG P V + +QV PPE+T+E S
Sbjct: 272 TGYNKTRFLLSNLLIDTTSEEDSGTYRCMADNGVGQPGAAVILYNVQVFEPPEVTMELSQ 331
Query: 270 VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFG 329
+ G A+L C V +PP V W +N+ PL +S+R+ +S R L + + PED G
Sbjct: 332 LVIPWGQSAKLTCEVRGNPPPSVLWLRNAVPLISSQRLRLSRR----ALRVLSMGPEDEG 387
Query: 330 NYSCVADNSLGRARRHVEV-SGRP 352
Y C+A+N +G A V++ + RP
Sbjct: 388 VYQCMAENEVGSAHAVVQLRTSRP 411
Score = 34.7 bits (76), Expect = 0.76
Identities = 47/175 (26%), Positives = 64/175 (36%), Gaps = 16/175 (9%)
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWH----RLNDSSSRLG---EGPQLQ 225
P V P + + GG +L C P VTW LN S LG L
Sbjct: 36 PQVTVQPAS--TVQKPGGTVILGC-VVEPPRMNVTWRLNGKELNGSDDALGVLITHGTLV 92
Query: 226 LSRLERHHGGVYACT--VDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCT 283
++ L H G Y C + G V L L ++ V+ + EG A + C
Sbjct: 93 ITALNNHTVGRYQCVARMPAGAVASVPATVTLANLQDFKLDVQHV-IEVDEGNTAVIACH 151
Query: 284 VL-ADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADN 337
+ + P A+V + L AS + N L I + ED G Y C A N
Sbjct: 152 LPESHPKAQVRYSVKQEWLEASRGNYLIMPSGN--LQIVNASQEDEGMYKCAAYN 204
>AK090455-1|BAC03436.1| 931|Homo sapiens FLJ00376 protein protein.
Length = 931
Score = 110 bits (265), Expect = 1e-23
Identities = 66/183 (36%), Positives = 95/183 (51%), Gaps = 15/183 (8%)
Query: 179 PETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGP------QLQLSRLERH 232
PE + + +G + +LEC A+G P P VTW + D SS G L +
Sbjct: 52 PEAQTIIVTKGQSLILECVASGIPPPRVTWAK--DGSSVTGYNKTRFLLSNLLIDTTSEE 109
Query: 233 HGGVYACTVDNGVGPP--VVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C DNGVG P V + +QV PPE+T+E S + G A+L C V +PP
Sbjct: 110 DSGTYRCMADNGVGQPGAAVILYNVQVFEPPEVTMELSQLVIPWGQSAKLTCEVRGNPPP 169
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV-S 349
V W +N+ PL +S+R+ +S R L + + PED G Y C+A+N +G A V++ +
Sbjct: 170 SVLWLRNAVPLISSQRLRLSRR----ALRVLSMGPEDEGVYQCMAENEVGSAHAVVQLRT 225
Query: 350 GRP 352
RP
Sbjct: 226 SRP 228
Score = 42.7 bits (96), Expect = 0.003
Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 8/97 (8%)
Query: 245 VGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
+ PP T +++YPPE + +G L C PP V+W ++ ++
Sbjct: 36 LAPPGSTAEAARIIYPPEAQT----IIVTKGQSLILECVASGIPPPRVTWAKDGSSVTGY 91
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGR 341
+ SN LLI ED G Y C+ADN +G+
Sbjct: 92 NKTRFLL--SN--LLIDTTSEEDSGTYRCMADNGVGQ 124
>U41901-1|AAC50569.1| 338|Homo sapiens LAMP protein.
Length = 338
Score = 107 bits (256), Expect = 1e-22
Identities = 72/245 (29%), Positives = 109/245 (44%), Gaps = 14/245 (5%)
Query: 120 GHTNVWETTRRITSEQHGNTNFRMIFQ-----DAGDYVCQISDR--VARDQVHTVEVLVP 172
GH W R+ E+ + + + Q D G Y C + + QV+ + V VP
Sbjct: 74 GHDK-WSLDPRVELEKRHSLEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLI-VQVP 131
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRL-GEGPQLQLSRLER 231
P + S + VT G L C A G P P +TW L + GE L++ + R
Sbjct: 132 PKI--SNISSDVTVNEGSNVTLVCMANGRPEPVITWRHLTPTGREFEGEEEYLEILGITR 189
Query: 232 HHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAE 291
G Y C N V V + ++ V YPP IT +S T G +A L C A P +
Sbjct: 190 EQSGKYECKAANEVSSADVKQVKVTVNYPPTITESKSNEAT-TGRQASLKCEASAVPAPD 248
Query: 292 VSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR 351
WY++ ++++ + + + +L + +V E +GNY+CVA N LG + V R
Sbjct: 249 FEWYRDDTRINSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAANKLGVTNASL-VLFR 307
Query: 352 PGPAR 356
PG R
Sbjct: 308 PGSVR 312
>L34774-1|AAA36387.1| 345|Homo sapiens opioid-binding cell adhesion
molecule protein.
Length = 345
Score = 107 bits (256), Expect = 1e-22
Identities = 66/212 (31%), Positives = 101/212 (47%), Gaps = 10/212 (4%)
Query: 147 DAGDYVC--QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C Q + +VH + V VPP + + +T G + L C A G P P
Sbjct: 109 DEGPYTCSVQTDNHPKTSRVHLI-VQVPPQIMNI--SSDITVNEGSSVTLLCLAIGRPEP 165
Query: 205 TVTWHRLN--DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE 262
TVTW L+ + + E L++S ++R G Y C+ N V P V + ++ V YPP
Sbjct: 166 TVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPY 225
Query: 263 ITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS-ERVTMSARGSNHTLLIA 321
I+ ++ G + L C A P AE W++ L+ + + + +G TL
Sbjct: 226 ISKAKN-TGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFF 284
Query: 322 DVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
+V +D+GNY+CVA N LG + + G PG
Sbjct: 285 NVSEKDYGNYTCVATNKLGNTNASITLYG-PG 315
>BX537377-1|CAD97619.1| 338|Homo sapiens hypothetical protein
protein.
Length = 338
Score = 107 bits (256), Expect = 1e-22
Identities = 66/212 (31%), Positives = 101/212 (47%), Gaps = 10/212 (4%)
Query: 147 DAGDYVC--QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C Q + +VH + V VPP + + +T G + L C A G P P
Sbjct: 102 DEGPYTCSVQTDNHPKTSRVHLI-VQVPPQIMNI--SSDITVNEGSSVTLLCLAIGRPEP 158
Query: 205 TVTWHRLN--DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE 262
TVTW L+ + + E L++S ++R G Y C+ N V P V + ++ V YPP
Sbjct: 159 TVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPY 218
Query: 263 ITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS-ERVTMSARGSNHTLLIA 321
I+ ++ G + L C A P AE W++ L+ + + + +G TL
Sbjct: 219 ISKAKN-TGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFF 277
Query: 322 DVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
+V +D+GNY+CVA N LG + + G PG
Sbjct: 278 NVSEKDYGNYTCVATNKLGNTNASITLYG-PG 308
>BC126251-1|AAI26252.1| 345|Homo sapiens opioid binding
protein/cell adhesion molecule-like protein.
Length = 345
Score = 107 bits (256), Expect = 1e-22
Identities = 66/212 (31%), Positives = 101/212 (47%), Gaps = 10/212 (4%)
Query: 147 DAGDYVC--QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C Q + +VH + V VPP + + +T G + L C A G P P
Sbjct: 109 DEGPYTCSVQTDNHPKTSRVHLI-VQVPPQIMNI--SSDITVNEGSSVTLLCLAIGRPEP 165
Query: 205 TVTWHRLN--DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE 262
TVTW L+ + + E L++S ++R G Y C+ N V P V + ++ V YPP
Sbjct: 166 TVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPY 225
Query: 263 ITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS-ERVTMSARGSNHTLLIA 321
I+ ++ G + L C A P AE W++ L+ + + + +G TL
Sbjct: 226 ISKAKN-TGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFF 284
Query: 322 DVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
+V +D+GNY+CVA N LG + + G PG
Sbjct: 285 NVSEKDYGNYTCVATNKLGNTNASITLYG-PG 315
>BC117254-1|AAI17255.1| 345|Homo sapiens opioid binding
protein/cell adhesion molecule-like protein.
Length = 345
Score = 107 bits (256), Expect = 1e-22
Identities = 66/212 (31%), Positives = 101/212 (47%), Gaps = 10/212 (4%)
Query: 147 DAGDYVC--QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C Q + +VH + V VPP + + +T G + L C A G P P
Sbjct: 109 DEGPYTCSVQTDNHPKTSRVHLI-VQVPPQIMNI--SSDITVNEGSSVTLLCLAIGRPEP 165
Query: 205 TVTWHRLN--DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE 262
TVTW L+ + + E L++S ++R G Y C+ N V P V + ++ V YPP
Sbjct: 166 TVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPY 225
Query: 263 ITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS-ERVTMSARGSNHTLLIA 321
I+ ++ G + L C A P AE W++ L+ + + + +G TL
Sbjct: 226 ISKAKN-TGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFF 284
Query: 322 DVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
+V +D+GNY+CVA N LG + + G PG
Sbjct: 285 NVSEKDYGNYTCVATNKLGNTNASITLYG-PG 315
>BC074773-1|AAH74773.1| 345|Homo sapiens opioid binding
protein/cell adhesion molecule-like protein.
Length = 345
Score = 107 bits (256), Expect = 1e-22
Identities = 66/212 (31%), Positives = 101/212 (47%), Gaps = 10/212 (4%)
Query: 147 DAGDYVC--QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C Q + +VH + V VPP + + +T G + L C A G P P
Sbjct: 109 DEGPYTCSVQTDNHPKTSRVHLI-VQVPPQIMNI--SSDITVNEGSSVTLLCLAIGRPEP 165
Query: 205 TVTWHRLN--DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE 262
TVTW L+ + + E L++S ++R G Y C+ N V P V + ++ V YPP
Sbjct: 166 TVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPY 225
Query: 263 ITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS-ERVTMSARGSNHTLLIA 321
I+ ++ G + L C A P AE W++ L+ + + + +G TL
Sbjct: 226 ISKAKN-TGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFF 284
Query: 322 DVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
+V +D+GNY+CVA N LG + + G PG
Sbjct: 285 NVSEKDYGNYTCVATNKLGNTNASITLYG-PG 315
>BC033803-1|AAH33803.1| 338|Homo sapiens limbic system-associated
membrane protein protein.
Length = 338
Score = 107 bits (256), Expect = 1e-22
Identities = 72/245 (29%), Positives = 109/245 (44%), Gaps = 14/245 (5%)
Query: 120 GHTNVWETTRRITSEQHGNTNFRMIFQ-----DAGDYVCQISDR--VARDQVHTVEVLVP 172
GH W R+ E+ + + + Q D G Y C + + QV+ + V VP
Sbjct: 74 GHDK-WSLDPRVELEKRHSLEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLI-VQVP 131
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRL-GEGPQLQLSRLER 231
P + S + VT G L C A G P P +TW L + GE L++ + R
Sbjct: 132 PKI--SNISSDVTVNEGSNVTLVCMANGRPEPVITWRHLTPTGREFEGEEEYLEILGITR 189
Query: 232 HHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAE 291
G Y C N V V + ++ V YPP IT +S T G +A L C A P +
Sbjct: 190 EQSGKYECKAANEVSSADVKQVKVTVNYPPTITESKSNEAT-TGRQASLKCEASAVPAPD 248
Query: 292 VSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR 351
WY++ ++++ + + + +L + +V E +GNY+CVA N LG + V R
Sbjct: 249 FEWYRDDTRINSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAANKLGVTNASL-VLFR 307
Query: 352 PGPAR 356
PG R
Sbjct: 308 PGSVR 312
>BC074742-1|AAH74742.1| 344|Homo sapiens opioid binding
protein/cell adhesion molecule-like protein.
Length = 344
Score = 103 bits (247), Expect = 1e-21
Identities = 65/211 (30%), Positives = 99/211 (46%), Gaps = 9/211 (4%)
Query: 147 DAGDYVC--QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C Q + +VH + V VPP + + +T G + L C A G P
Sbjct: 109 DEGPYTCSVQTDNHPKTSRVHLI-VQVPPQIMNI--SSDITVNEGSSVTLLCLAIGRSEP 165
Query: 205 TVTWHRLN-DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEI 263
TVTW L+ + E L++S ++R G Y C+ N V P V + ++ V YPP I
Sbjct: 166 TVTWRHLSVKGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYI 225
Query: 264 TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS-ERVTMSARGSNHTLLIAD 322
+ ++ G + L C A P AE W++ L+ + + + +G TL +
Sbjct: 226 SKAKN-TGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFN 284
Query: 323 VQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
V +D+GNY+CVA N LG + + G PG
Sbjct: 285 VSEKDYGNYTCVATNKLGNTNASITLYG-PG 314
>AY358331-1|AAQ88697.1| 344|Homo sapiens HNT protein.
Length = 344
Score = 102 bits (245), Expect = 3e-21
Identities = 65/211 (30%), Positives = 95/211 (45%), Gaps = 9/211 (4%)
Query: 147 DAGDYVC--QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C Q + +VH + + P V S + ++ G L C A G P P
Sbjct: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEISSD---ISINEGNNISLTCIATGRPEP 165
Query: 205 TVTWHRLNDSS-SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEI 263
TVTW ++ + + E L++ + R G Y C+ N V PVV ++ V YPP I
Sbjct: 166 TVTWRHISPKAVGFVSEDEYLEIQGITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYI 225
Query: 264 TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASER-VTMSARGSNHTLLIAD 322
+ E G + L C A P AE WY++ L ++ V + R L+ +
Sbjct: 226 S-EAKGTGVPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFN 284
Query: 323 VQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
V D+GNY+CVA N LG + + G PG
Sbjct: 285 VSEHDYGNYTCVASNKLGHTNASIMLFG-PG 314
Score = 38.7 bits (86), Expect = 0.047
Identities = 43/175 (24%), Positives = 72/175 (41%), Gaps = 19/175 (10%)
Query: 88 ITDVGPQI-RYTVDVTIYENSETSVALAILGATGHTNVWE--TTRRI--TSEQHGNTNFR 142
I V P+I + D++I E + S+ G T W + + + SE
Sbjct: 131 IVQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQG 190
Query: 143 MIFQDAGDYVCQISDRVARDQVHTVEVLV--PPSVRASPETRHVTARRGGAAVLECRAAG 200
+ + +GDY C S+ VA V V+V V PP + + T ++G L+C A+
Sbjct: 191 ITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKG---TLQCEASA 247
Query: 201 NPVPTVTWHRLNDSSSRLGEGPQLQ----LSRL-----ERHHGGVYACTVDNGVG 246
P W++ + +G +++ LS+L H G Y C N +G
Sbjct: 248 VPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLG 302
>AF126426-1|AAF37591.1| 344|Homo sapiens neurotrimin protein.
Length = 344
Score = 102 bits (245), Expect = 3e-21
Identities = 65/211 (30%), Positives = 95/211 (45%), Gaps = 9/211 (4%)
Query: 147 DAGDYVC--QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C Q + +VH + + P V S + ++ G L C A G P P
Sbjct: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEISSD---ISINEGNNISLTCIATGRPEP 165
Query: 205 TVTWHRLNDSS-SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEI 263
TVTW ++ + + E L++ + R G Y C+ N V PVV ++ V YPP I
Sbjct: 166 TVTWRHISPKAVGFVSEDEYLEIQGITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYI 225
Query: 264 TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASER-VTMSARGSNHTLLIAD 322
+ E G + L C A P AE WY++ L ++ V + R L+ +
Sbjct: 226 S-EAKGTGVPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFN 284
Query: 323 VQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
V D+GNY+CVA N LG + + G PG
Sbjct: 285 VSEHDYGNYTCVASNKLGHTNASIMLFG-PG 314
Score = 38.7 bits (86), Expect = 0.047
Identities = 43/175 (24%), Positives = 72/175 (41%), Gaps = 19/175 (10%)
Query: 88 ITDVGPQI-RYTVDVTIYENSETSVALAILGATGHTNVWE--TTRRI--TSEQHGNTNFR 142
I V P+I + D++I E + S+ G T W + + + SE
Sbjct: 131 IVQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQG 190
Query: 143 MIFQDAGDYVCQISDRVARDQVHTVEVLV--PPSVRASPETRHVTARRGGAAVLECRAAG 200
+ + +GDY C S+ VA V V+V V PP + + T ++G L+C A+
Sbjct: 191 ITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKG---TLQCEASA 247
Query: 201 NPVPTVTWHRLNDSSSRLGEGPQLQ----LSRL-----ERHHGGVYACTVDNGVG 246
P W++ + +G +++ LS+L H G Y C N +G
Sbjct: 248 VPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLG 302
>BC050716-1|AAH50716.1| 316|Homo sapiens HNT protein protein.
Length = 316
Score = 101 bits (243), Expect = 4e-21
Identities = 63/208 (30%), Positives = 93/208 (44%), Gaps = 8/208 (3%)
Query: 147 DAGDYVC--QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C Q + +VH + + P V S + ++ G L C A G P P
Sbjct: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEISSD---ISINEGNNISLTCIATGRPEP 165
Query: 205 TVTWHRLNDSS-SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEI 263
TVTW ++ + + E L++ + R G Y C+ N V PVV ++ V YPP I
Sbjct: 166 TVTWRHISPKAVGFVSEDEYLEIQGITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYI 225
Query: 264 TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASER-VTMSARGSNHTLLIAD 322
+ E G + L C A P AE WY++ L ++ V + R L+ +
Sbjct: 226 S-EAKGTGVPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFN 284
Query: 323 VQPEDFGNYSCVADNSLGRARRHVEVSG 350
V D+GNY+CVA N LG + + G
Sbjct: 285 VSEHDYGNYTCVASNKLGHTNASIMLFG 312
Score = 38.7 bits (86), Expect = 0.047
Identities = 43/175 (24%), Positives = 72/175 (41%), Gaps = 19/175 (10%)
Query: 88 ITDVGPQI-RYTVDVTIYENSETSVALAILGATGHTNVWE--TTRRI--TSEQHGNTNFR 142
I V P+I + D++I E + S+ G T W + + + SE
Sbjct: 131 IVQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQG 190
Query: 143 MIFQDAGDYVCQISDRVARDQVHTVEVLV--PPSVRASPETRHVTARRGGAAVLECRAAG 200
+ + +GDY C S+ VA V V+V V PP + + T ++G L+C A+
Sbjct: 191 ITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKG---TLQCEASA 247
Query: 201 NPVPTVTWHRLNDSSSRLGEGPQLQ----LSRL-----ERHHGGVYACTVDNGVG 246
P W++ + +G +++ LS+L H G Y C N +G
Sbjct: 248 VPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLG 302
>EF043567-1|ABK34282.1| 355|Homo sapiens neurotrimin variant 3
protein.
Length = 355
Score = 100 bits (240), Expect = 1e-20
Identities = 62/204 (30%), Positives = 91/204 (44%), Gaps = 8/204 (3%)
Query: 147 DAGDYVC--QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C Q + +VH + + P V S + ++ G L C A G P P
Sbjct: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEISSD---ISINEGNNISLTCIATGRPEP 165
Query: 205 TVTWHRLNDSS-SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEI 263
TVTW ++ + + E L++ + R G Y C+ N V PVV ++ V YPP I
Sbjct: 166 TVTWRHISPKAVGFVSEDEYLEIQGITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYI 225
Query: 264 TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASER-VTMSARGSNHTLLIAD 322
+ E G + L C A P AE WY++ L ++ V + R L+ +
Sbjct: 226 S-EAKGTGVPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFN 284
Query: 323 VQPEDFGNYSCVADNSLGRARRHV 346
V D+GNY+CVA N LG +
Sbjct: 285 VSEHDYGNYTCVASNKLGHTNASI 308
Score = 38.7 bits (86), Expect = 0.047
Identities = 43/175 (24%), Positives = 72/175 (41%), Gaps = 19/175 (10%)
Query: 88 ITDVGPQI-RYTVDVTIYENSETSVALAILGATGHTNVWE--TTRRI--TSEQHGNTNFR 142
I V P+I + D++I E + S+ G T W + + + SE
Sbjct: 131 IVQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQG 190
Query: 143 MIFQDAGDYVCQISDRVARDQVHTVEVLV--PPSVRASPETRHVTARRGGAAVLECRAAG 200
+ + +GDY C S+ VA V V+V V PP + + T ++G L+C A+
Sbjct: 191 ITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKG---TLQCEASA 247
Query: 201 NPVPTVTWHRLNDSSSRLGEGPQLQ----LSRL-----ERHHGGVYACTVDNGVG 246
P W++ + +G +++ LS+L H G Y C N +G
Sbjct: 248 VPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLG 302
>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone RP11-465I11 on chromosome 1. ).
Length = 5635
Score = 98.3 bits (234), Expect = 5e-20
Identities = 61/215 (28%), Positives = 97/215 (45%), Gaps = 15/215 (6%)
Query: 146 QDAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C + + ++ + + VLVPP + V + + L C GNPVP
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509
Query: 205 TVTWHR----LNDSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TWH+ L + + + G LQ++ ++ H G Y C + G F L V
Sbjct: 2510 EITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHK-SRSFSLNVF 2568
Query: 259 YPPEITVERSWVHTGE-----GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
P I S + + LVC + PPA ++W+++ PL ++ + + G
Sbjct: 2569 VSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGG 2628
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
TL I + Q ++ G YSCVA N G +H EV
Sbjct: 2629 --RTLQILNAQEDNAGRYSCVATNEAGEMIKHYEV 2661
Score = 96.3 bits (229), Expect = 2e-19
Identities = 66/222 (29%), Positives = 100/222 (45%), Gaps = 15/222 (6%)
Query: 146 QDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
QD G Y C+ ++ + ++ + V + VPP++ S E +T G L C ++G P P
Sbjct: 2167 QDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPP 2226
Query: 205 TVTWHR-----LNDSSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
+ W + L DS R L G QLQ+S E+ +Y+C N G E+ LQ
Sbjct: 2227 NLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT-AKKEYNLQ 2285
Query: 257 VLYPPEITVERSW---VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
V P IT S + G L C V PP V+W ++ PL ++ V + G
Sbjct: 2286 VYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEG 2345
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
H L + ++ D G Y CVA N G + ++S P+
Sbjct: 2346 --HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPS 2385
Score = 91.9 bits (218), Expect = 5e-18
Identities = 57/214 (26%), Positives = 95/214 (44%), Gaps = 9/214 (4%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
+ + +DAG Y C ++ Q H + V PPS+ + + + T LEC+AAG
Sbjct: 1887 KTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAG 1946
Query: 201 NPVPTVTWHR----LNDSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
NPVP +TW++ L+ S+S L G + + + G+Y C N G + +
Sbjct: 1947 NPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELF-YS 2005
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
LQV P I+ + V L C P ++W ++ P+S+ +
Sbjct: 2006 LQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSG 2064
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
L + Q D G Y+CVA N+ G +R +++
Sbjct: 2065 GRILALTSAQISDTGRYTCVAVNAAGEKQRDIDL 2098
Score = 87.8 bits (208), Expect = 8e-17
Identities = 67/211 (31%), Positives = 92/211 (43%), Gaps = 17/211 (8%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G YVC+ + RD + + V VPPS+ PE + L C A G P PT
Sbjct: 3124 DTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG-PEREVIVETISNPVTLTCDATGIPPPT 3182
Query: 206 VTW----HRLNDSSSR----LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W R+ +S S L G +LQ++R + G Y C N G F L +
Sbjct: 3183 IAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYF-LSI 3241
Query: 258 LYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA--SERVTMSARG 313
PP + S V G ELVC P + W ++ P+++ +ER+ +SA G
Sbjct: 3242 QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG 3301
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
S TL I D G Y+CVA N G R
Sbjct: 3302 S--TLNIYGALTSDTGKYTCVATNPAGEEDR 3330
Score = 87.4 bits (207), Expect = 1e-16
Identities = 59/203 (29%), Positives = 88/203 (43%), Gaps = 12/203 (5%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D Y C S+R D H ++V PP++ S T +T +G + + C G P P+
Sbjct: 3407 DVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPS 3466
Query: 206 VTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W R L+ + G LQL + E G Y C N G V F L+VL
Sbjct: 3467 MAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG-EVSKHFILKVLE 3525
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + E + EL C P +++W ++ PL +++V G
Sbjct: 3526 PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQV--QTLGGGEV 3583
Query: 318 LLIADVQPEDFGNYSCVADNSLG 340
L I+ Q ED G Y+C+A + G
Sbjct: 3584 LRISTAQVEDTGRYTCLASSPAG 3606
Score = 86.6 bits (205), Expect = 2e-16
Identities = 73/280 (26%), Positives = 117/280 (41%), Gaps = 22/280 (7%)
Query: 91 VGPQIRYTVD-VTIYENSETSVALAILGATGHTNVWETTR--------RITSEQHGNTNF 141
V P+IR T T+ ENS+ + G W+ + T+E +G
Sbjct: 4167 VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELIL 4226
Query: 142 R-MIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ +D+G Y C +++ A + HTV + V + V+ +G L C+A G
Sbjct: 4227 ENVVLEDSGFYTC-VANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATG 4285
Query: 201 NPVPTVTWHRLND----SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P+P +TW N+ + +L + R+ + G Y CT +N VG F +
Sbjct: 4286 IPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGF-VY 4344
Query: 257 VLYPPEITVE--RSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP + +W+ G A L C V DP + W + + S R+ GS
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGG-NAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGS 4403
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
L I ED G+Y+CVA N G R + ++ + P
Sbjct: 4404 ---LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 86.2 bits (204), Expect = 2e-16
Identities = 54/217 (24%), Positives = 96/217 (44%), Gaps = 10/217 (4%)
Query: 147 DAGDYVCQISDRVARDQV-HTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C + ++ + V+VLVPP++ ET + L+C G+P PT
Sbjct: 1706 DRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPT 1765
Query: 206 VTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W + D L G +L +++ + + G+Y C N G EF++ V
Sbjct: 1766 IMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH-KKEFEVTVHV 1824
Query: 260 PPEITVERSWVHTGEGFR-AELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP I ++ L C P ++W ++ P++ ++ + + S L
Sbjct: 1825 PPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKIQSSGRVL 1883
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
IA ED G Y+CVA N+ G ++H+++ P+
Sbjct: 1884 QIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPS 1920
Score = 86.2 bits (204), Expect = 2e-16
Identities = 61/219 (27%), Positives = 96/219 (43%), Gaps = 11/219 (5%)
Query: 147 DAGDYVC-QISDRVARDQVHTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNPV 203
D G+Y C I+ + ++ V VPPS++ S V R G + LEC + P
Sbjct: 3029 DGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPP 3088
Query: 204 PTVTWHR----LNDSS--SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P +TW++ + +S+ L +G L + + E G Y C N G F L V
Sbjct: 3089 PVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDD-KNFHLNV 3147
Query: 258 LYPPEIT-VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP I ER + L C PP ++W +N + S+ + +
Sbjct: 3148 YVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGS 3207
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L IA Q D GNY+C+A N G+A+++ +S + P+
Sbjct: 3208 KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPS 3246
Score = 84.6 bits (200), Expect = 7e-16
Identities = 62/214 (28%), Positives = 93/214 (43%), Gaps = 13/214 (6%)
Query: 142 RMIFQDAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
R+ +D+G YVC + V + + V V PP + + + GG A+L C G
Sbjct: 4317 RVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL-GGNAILNCEVKG 4375
Query: 201 NPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
+P PT+ W+R ++ +LG G L + G Y C N G V
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQLGNG-SLAIYGTVNEDAGDYTCVATNEAG-VVERSMS 4433
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
L + PP IT+E G + L C +P ++W + +S +RV + S
Sbjct: 4434 LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL---S 4490
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
N++L IAD Q ED + CVA N +G V V
Sbjct: 4491 NNSLYIADAQKEDTSEFECVARNLMGSVLVRVPV 4524
Score = 82.6 bits (195), Expect = 3e-15
Identities = 57/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 128 TRRITSEQHGNTN--FRMIFQDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHV 184
T RI +G+T + + D G Y C ++ D++ + V V P++R + +
Sbjct: 3292 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEK 3351
Query: 185 TARRGGAAV-LECRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVY 237
++ +ECRA G P P + W + L+ L G +++ R + VY
Sbjct: 3352 LMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVY 3411
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWY 295
C N G + LQV PP + ++ + +G + C P ++W
Sbjct: 3412 TCVASNRAGVDN-KHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWL 3470
Query: 296 QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
++ PL +T+S G LL A+ ED G Y+C+A N G +H
Sbjct: 3471 RDGQPLGLDAHLTVSTHGMVLQLLKAET--EDSGKYTCIASNEAGEVSKH 3518
Score = 82.2 bits (194), Expect = 4e-15
Identities = 61/210 (29%), Positives = 93/210 (44%), Gaps = 15/210 (7%)
Query: 146 QDAGDYVCQISDRVARDQV-HTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNP 202
+DAG Y C + D + + V VLVPP ++ S VT +A++EC ++G+P
Sbjct: 2841 EDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSP 2900
Query: 203 VPTVTWHR-----LNDSSSR-LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P +W + L D + L G LQ+ + G Y C +N G F L
Sbjct: 2901 APRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGS-AKKYFNLN 2959
Query: 257 VLYPPEITVERSWVHTG--EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP + +S T F L C V PP ++SW +N P+ + + G
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNF-ISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGG- 3017
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARR 344
TL I + D G Y+C+A N G +++
Sbjct: 3018 -RTLQIIRAKVSDGGEYTCIAINQAGESKK 3046
Score = 81.0 bits (191), Expect = 9e-15
Identities = 60/200 (30%), Positives = 85/200 (42%), Gaps = 13/200 (6%)
Query: 148 AGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
AG Y C + H T+ V PP ++ P HV +L C A G P P +
Sbjct: 3962 AGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNN--PILLPCEATGTPSPFI 4019
Query: 207 TWHR----LNDSSSRLGEGPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
TW + +N S P LQ+SR R G Y C N G + + +L V P
Sbjct: 4020 TWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGT-ALGKIKLNVQVP 4078
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I+ L C PP +++W+++ + S R + + GS L I
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGS---LQI 4135
Query: 321 ADVQPEDFGNYSCVADNSLG 340
A VQP D G+Y+C+A N G
Sbjct: 4136 AFVQPGDAGHYTCMAANVAG 4155
Score = 76.6 bits (180), Expect = 2e-13
Identities = 79/315 (25%), Positives = 125/315 (39%), Gaps = 31/315 (9%)
Query: 84 YNLQITDVGPQIR---YTVDVTIYENSETSVALAILGATGHTNVW-----ETTRRITSEQ 135
YNL++ V P I+ +V++ N T++ + G +W + T T +
Sbjct: 1351 YNLKV-HVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQT 1409
Query: 136 HGNTNFRMIF----QDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGG 190
N +F +DAG Y C+ + Q + ++VLVPP++ + V+
Sbjct: 1410 VNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNR 1469
Query: 191 AAVLECRAAGNPVPTVTWHR------LNDSS-SRLGEGPQLQLSRLERHHGGVYACTVDN 243
LEC+ G P P + W + L D + L G L L R+ G Y CTV N
Sbjct: 1470 DVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSN 1529
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRA--ELVCTVLADPPAEVSWYQNSFPL 301
G + +L + PP I + +L C P ++WY++ P+
Sbjct: 1530 AAGKQ-AKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPI 1588
Query: 302 SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTS 359
+S + +G L I Q D Y+C N G A + HV+V P +
Sbjct: 1589 MSSSQALYIDKG--QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLA 1646
Query: 360 PPLAR---APHSYTL 371
PL + HS TL
Sbjct: 1647 TPLNKQVVIAHSLTL 1661
Score = 76.6 bits (180), Expect = 2e-13
Identities = 60/225 (26%), Positives = 93/225 (41%), Gaps = 21/225 (9%)
Query: 149 GDYVCQISDRVA-RDQVHTVEVLVPPSVR---ASPETRHVTARRGGAAVLECRAAGNPVP 204
G Y C S + + ++ V V P++ + VT L C A P
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPA 2605
Query: 205 TVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
T+TW + N + L G LQ+ + + G Y+C N G ++ ++++V
Sbjct: 2606 TITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGE-MIKHYEVKVY 2664
Query: 259 YPPEITVERSW--------VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
PP I W V L C A P A +SWY++ PL + + V ++
Sbjct: 2665 IPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIA 2724
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
A G HTL I + Q D G Y+CVA N G +V+ + P+
Sbjct: 2725 ANG--HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPS 2767
Score = 75.8 bits (178), Expect = 3e-13
Identities = 64/227 (28%), Positives = 91/227 (40%), Gaps = 18/227 (7%)
Query: 146 QDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G Y C S D + + V V VPP++ + E R +T R LEC++ P P
Sbjct: 3592 EDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 205 TVTWHRLND---SSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TW R + ++ R L G LQ++ + Y C N G EF L V
Sbjct: 3652 VITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAG-KTTREFILTVN 3710
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNHT 317
PP I + L C P ++W ++ L+ + R ++ G H
Sbjct: 3711 VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH- 3769
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARR------HVEVSGRPGPARFT 358
I D G Y C+A N+ G RR HV S PGP T
Sbjct: 3770 --IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMT 3814
Score = 75.4 bits (177), Expect = 4e-13
Identities = 62/214 (28%), Positives = 94/214 (43%), Gaps = 18/214 (8%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTV-EVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ D G Y C + T +V PP V P +VT G AVL C
Sbjct: 488 KVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPN--NVTVTPGERAVLTCLIIS 545
Query: 201 NPVPTVTWHRLNDSSSRLGEGPQ--------LQLSRLERHHGGVYACTVDNGVGPPVVTE 252
+TW R ND RL E + L+L ++ + G Y C V + G +
Sbjct: 546 AVDYNLTWQR-NDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASV 604
Query: 253 FQLQVLYPPEITV-ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA 311
F L V PP++TV ++ TG G ++C+ P +++W N + S R M++
Sbjct: 605 F-LTVQEPPKVTVMPKNQSFTG-GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTS 662
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
G TL I + P+D G Y C+A NS G +++
Sbjct: 663 DG---TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693
Score = 73.7 bits (173), Expect = 1e-12
Identities = 60/211 (28%), Positives = 88/211 (41%), Gaps = 18/211 (8%)
Query: 147 DAGDYVCQISDRVARDQVHTVE--VLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D+G Y+C ++ +A + V+ V VPP ++ P +H+ + G + C A G P+P
Sbjct: 1144 DSGMYLC-VATNIAGNVTQAVKLNVHVPPKIQRGP--KHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 205 TVTWHRLNDSSSRLGE----GPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TW + + GE P L + + G+Y C N G TE L V
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTD-ETEITLHVQ 1259
Query: 259 YPPEI-TVERSWVHTGE----GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
PP + +E + T + R E C P + W N L+ E +S
Sbjct: 1260 EPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGRE-PGISILE 1318
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
L+IA V P D G Y CVA N G R
Sbjct: 1319 DGTLLVIASVTPYDNGEYICVAVNEAGTTER 1349
Score = 73.7 bits (173), Expect = 1e-12
Identities = 56/219 (25%), Positives = 89/219 (40%), Gaps = 13/219 (5%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C +S+ + + + +PPS++ T ++ LEC G P+P
Sbjct: 1519 DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPA 1578
Query: 206 VTWHRLND---SSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+TW++ SSS+ + +G L + R + Y C V N G F + V
Sbjct: 1579 ITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAG-TAEKSFHVDVYV 1637
Query: 260 PPEITVERSWVHTGEGFRAE---LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP I + + A L C +P ++W ++ P+ A++ + + A G
Sbjct: 1638 PPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKK- 1696
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L I Q D G Y CVA + G EV PA
Sbjct: 1697 -LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPA 1734
Score = 72.9 bits (171), Expect = 2e-12
Identities = 75/332 (22%), Positives = 123/332 (37%), Gaps = 28/332 (8%)
Query: 88 ITDVGPQIRYTVDVTIYENSETSVALAILGATGHTNVWETT---------RRITSEQHGN 138
+++ P I+ +VT+ + I+ A + W+ RI + + +
Sbjct: 516 VSEPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS 575
Query: 139 TNFRMI-FQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLEC 196
+ + F DAG+Y C +S + V PP V P+ + T G + C
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTG--GSEVSIMC 633
Query: 197 RAAGNPVPTVTWHRLNDS------SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVV 250
A G P P + W +ND R+ L + G+Y C N G
Sbjct: 634 SATGYPKPKIAW-TVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQ 692
Query: 251 TEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
L+ + P++ V +S + G + C PP +V W++ L S + +
Sbjct: 693 NS-TLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIID 751
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPP--LARAPHS 368
L I + Q D G+Y+CVA N GRA + + P P +
Sbjct: 752 PLLG--LLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSN 809
Query: 369 YTLSFAVDSYPPLDELRLLYRQLAINESFQQP 400
TL V YP E + +R+L F +P
Sbjct: 810 VTLPCYVQGYP---EPTIKWRRLDNMPIFSRP 838
Score = 71.7 bits (168), Expect = 5e-12
Identities = 60/213 (28%), Positives = 90/213 (42%), Gaps = 16/213 (7%)
Query: 147 DAGDYVCQISDRVARDQVHT---VEVLVPPSVRASPETRHVTARRGGAAVLECRA-AGNP 202
D G Y+C+ ++ + Q T V LV P + SP +V G L C AGNP
Sbjct: 861 DKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVI--EGQQLTLPCTLLAGNP 918
Query: 203 VPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPP-VVTEFQLQ 256
+P W + L + + L + R++ GG Y C N G T +
Sbjct: 919 IPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH 978
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
VL P I + + T EG L C +P V W + +S S SA G++
Sbjct: 979 VL--PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSS-AKFSA-GADG 1034
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+L + E+ G Y C A N+ G A+R V+++
Sbjct: 1035 SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLT 1067
Score = 71.3 bits (167), Expect = 7e-12
Identities = 75/306 (24%), Positives = 120/306 (39%), Gaps = 31/306 (10%)
Query: 100 DVTIYENSETSVALAILGATGHTNVWETTRRITSEQHGNTNFRMI-----------FQDA 148
++T+ N +T++A G + W + + ++R++ D
Sbjct: 3812 NMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 3871
Query: 149 GDYVCQISDRVARDQVHTVE--VLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
Y C +++ A D TV+ V VPPS+ P VT + AV+ C A+G P P++
Sbjct: 3872 ATYECTVTNG-AGDDKRTVDLTVQVPPSIADEPTDFLVT--KHAPAVITCTASGVPFPSI 3928
Query: 207 TWHRLNDSSSRLGEGPQL------QLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
W + G+G ++ ++ + +H G Y C N G L V P
Sbjct: 3929 HWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGS-AHRHVTLHVHEP 3987
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I + S +H L C P ++W + ++ S R A + L I
Sbjct: 3988 PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGR--NHAVLPSGGLQI 4045
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR----APHSYTLSFAVD 376
+ ED G Y CVA N G A ++++ + P SP L TLS D
Sbjct: 4046 SRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPV--ISPHLKEYVIAVDKPITLSCEAD 4103
Query: 377 SYPPLD 382
PP D
Sbjct: 4104 GLPPPD 4109
Score = 70.9 bits (166), Expect = 1e-11
Identities = 58/209 (27%), Positives = 86/209 (41%), Gaps = 14/209 (6%)
Query: 147 DAGDYVCQISDRVAR-DQVHTVEVLVPPSVRAS-PETRHVTARRGGAAVLECRAAGNPVP 204
DA Y C S+ + + ++V + P++ S + RG + LEC G P P
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 205 TVTW----HRLNDSS--SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
TVTW H L + L EG LQL + G Y C N G ++ L V
Sbjct: 2323 TVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG-MTDKKYDLSVH 2381
Query: 259 YPPEITVER---SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
PP I + E L C P ++W+++ +P+S S V + + G
Sbjct: 2382 APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGG-- 2439
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARR 344
L + ED G Y+CV N+ G R+
Sbjct: 2440 RMLRLMQTTMEDAGQYTCVVRNAAGEERK 2468
Score = 70.9 bits (166), Expect = 1e-11
Identities = 61/210 (29%), Positives = 86/210 (40%), Gaps = 16/210 (7%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C ++ D+ ++V VPPS+ P ++T L C A G P P+
Sbjct: 3777 DTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPT--NMTVIVNVQTTLACEATGIPKPS 3834
Query: 206 VTW----HRLN----DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W H LN +S RL L + Y CTV NG G T L V
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRT-VDLTV 3893
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL-SASERVTMSARGSNH 316
PP I E + + A + CT P + W +N L + + + G+
Sbjct: 3894 QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGA-- 3951
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHV 346
+ I Q G Y+CVA N+ G A RHV
Sbjct: 3952 -IEILATQLNHAGRYTCVARNAAGSAHRHV 3980
Score = 69.7 bits (163), Expect = 2e-11
Identities = 56/201 (27%), Positives = 83/201 (41%), Gaps = 14/201 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
DAG Y C ++ T + V VPP +R++ H T A+L C A G P P
Sbjct: 4142 DAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG--HYTVNENSQAILPCVADGIPTPA 4199
Query: 206 VTWHRLND-SSSRLGEGP-----QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W + N ++ LG+ +L L + G Y C +N G T L V
Sbjct: 4200 INWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHT-VSLTVHV 4258
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
P T V +G + L C P +++W N+ + A + + L+
Sbjct: 4259 LPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAH----FDSVNGHSELV 4314
Query: 320 IADVQPEDFGNYSCVADNSLG 340
I V ED G Y C A+NS+G
Sbjct: 4315 IERVSKEDSGTYVCTAENSVG 4335
Score = 69.3 bits (162), Expect = 3e-11
Identities = 54/223 (24%), Positives = 90/223 (40%), Gaps = 14/223 (6%)
Query: 147 DAGDYVC---QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D +Y C I+ + R+ + TV V PP+++ P++ + + + VLEC A G P
Sbjct: 3686 DTANYTCVASNIAGKTTREFILTVNV--PPNIKGGPQSLVILLNK--STVLECIAEGVPT 3741
Query: 204 PTVTWHR----LNDSSSRLG--EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P +TW + L + +R E L + G Y C N G LQV
Sbjct: 3742 PRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDR-RRIDLQV 3800
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + + + L C P ++W +N L+ + S+ +
Sbjct: 3801 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS 3860
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
L+I +D Y C N G +R V+++ + P+ P
Sbjct: 3861 LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEP 3903
Score = 68.9 bits (161), Expect = 4e-11
Identities = 52/213 (24%), Positives = 94/213 (44%), Gaps = 13/213 (6%)
Query: 147 DAGDYVC-QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G+Y+C +++ ++ + ++V VPP ++ + +V+ L C G P P
Sbjct: 1332 DNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPI 1391
Query: 206 VTWHRLN----DSSS--RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W++ N +SS+ + G L+L R G Y+C N G F + VL
Sbjct: 1392 IMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTS-QKYFNIDVLV 1450
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNH 316
PP I T + V L C V P ++ W+++ PL + V + RG
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG--Q 1508
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
L + + + D G Y C N+ G+ + ++++
Sbjct: 1509 VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 1541
Score = 68.1 bits (159), Expect = 7e-11
Identities = 55/211 (26%), Positives = 81/211 (38%), Gaps = 15/211 (7%)
Query: 147 DAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D+G+Y C S+ + Q + + + VPPSV + V+ G L C A G P P
Sbjct: 3218 DSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 206 VTWHR-----LNDSSSRL---GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W + + + R+ G L + G Y C N G F L V
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI-FNLNV 3336
Query: 258 LYPPEITV---ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
P I E + T + C PP +++W +N PL S + + A G
Sbjct: 3337 YVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG- 3395
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
+ I Q D Y+CVA N G +H
Sbjct: 3396 -QVIRIVRAQVSDVAVYTCVASNRAGVDNKH 3425
Score = 67.7 bits (158), Expect = 9e-11
Identities = 70/277 (25%), Positives = 110/277 (39%), Gaps = 41/277 (14%)
Query: 100 DVTIYENSETSVALAILGATGHTNVW-------ETTRRITSEQHGNTNFRMIFQD--AGD 150
DVT+ NS TS+ T W E+ R I G T + Q+ AG
Sbjct: 2584 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGR 2643
Query: 151 YVCQISDRVARDQVH-TVEVLVPPSVRASP------ETRHVTARRGGAAVLECRAAGNPV 203
Y C ++ H V+V +PP + + V + LEC A P
Sbjct: 2644 YSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPS 2703
Query: 204 PTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+++W++ +D + G LQ+ + G Y C N G + +F + +
Sbjct: 2704 ASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL-DFDVNI 2762
Query: 258 LYPPEITVERSW-----VHTGEGFRAE---------LVCTVLADPPAEVSWYQNSFPLSA 303
PP ++ W + TG A+ L C A PP ++WY++ PL++
Sbjct: 2763 QVPPSF--QKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS 2820
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
S++V + G L I + ED G Y+CVA N G
Sbjct: 2821 SDKVLILPGG--RVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 66.9 bits (156), Expect = 2e-10
Identities = 69/260 (26%), Positives = 107/260 (41%), Gaps = 27/260 (10%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHV--TARRGGAA--------VLE 195
D G Y C S+ D++ V + VPPS + E ++ T R G A L
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 196 CRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPV 249
C P PT+TW++ +D L G LQ+ R + G Y C N G
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Query: 250 VTEFQLQVLYPPEITVERS----WVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE 305
+ ++ ++VL PP I S V A + C P SW ++ PL +
Sbjct: 2859 L-QYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD 2917
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF--TSPPLA 363
+ G L I + Q D G Y CVA+N+ G A+++ ++ P+ S L
Sbjct: 2918 HHKFLSNG--RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLT 2975
Query: 364 RAPHSY-TLSFAVDSYPPLD 382
+++ +L+ V +PP D
Sbjct: 2976 VVVNNFISLTCEVSGFPPPD 2995
Score = 64.1 bits (149), Expect = 1e-09
Identities = 61/235 (25%), Positives = 99/235 (42%), Gaps = 21/235 (8%)
Query: 131 ITSEQHGNTNF-RMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRG 189
IT G+ + R+ QD G+Y C ++ VA T V+V + ++ G
Sbjct: 937 ITVRSDGSLHIERVQLQDGGEYTC-VASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEG 995
Query: 190 GAAVLECRAAGNPVPTVTWHR----LNDSSSRLGEGPQLQLSRLER--HHGGVYACTVDN 243
L C+A+GNP P+V W + ++ SS++ G L + G Y CT N
Sbjct: 996 IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGE--------GFRAELVCTVLADPPAEVSWY 295
G + QL V P + ++ + + G L C V + PP ++W
Sbjct: 1056 TAGY-AKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 1114
Query: 296 QNSFPLSA-SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+ + +S S R T GS + I + + D G Y CVA N G + V+++
Sbjct: 1115 KETQLISPFSPRHTFLPSGS---MKITETRTSDSGMYLCVATNIAGNVTQAVKLN 1166
Score = 60.1 bits (139), Expect = 2e-08
Identities = 60/248 (24%), Positives = 95/248 (38%), Gaps = 17/248 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C + Q + V VPP++ E ++V+ A L C++ P PT
Sbjct: 2077 DTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMG--EEQNVSVLISQAVELLCQSDAIPPPT 2134
Query: 206 VTWHR-----LNDSSSRLGEGPQ-LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+TW + L + E L++ + G Y C N G + + +
Sbjct: 2135 LTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK-TEKNYNVNIWV 2193
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + E + + EG L+C PP + W + P+ +
Sbjct: 2194 PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQ 2253
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTSPP---LARAPHSYTLS 372
L I+ + D YSCVA N G A++ +++V RP S P + S +L
Sbjct: 2254 LQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLE 2313
Query: 373 FAVDSYPP 380
V PP
Sbjct: 2314 CEVQGIPP 2321
Score = 58.0 bits (134), Expect = 7e-08
Identities = 61/229 (26%), Positives = 92/229 (40%), Gaps = 14/229 (6%)
Query: 146 QDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C S+ D Q T+ + P + V G V+EC+ +G P P
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVAL--GDITVMECKTSGIPPP 731
Query: 205 TVTWHRLN---DSSSRLGEGPQLQLSRLERHH---GGVYACTVDNGVGPPVVTEFQLQVL 258
V W + + S+ L P L L +++ G Y C N G + L V
Sbjct: 732 QVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGR-ATGKITLDVG 790
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ-NSFPL-SASERVTMSARGSNH 316
PP E + V G L C V P + W + ++ P+ S V+ ++
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRH--VEVSGRPGPARFTSPPLA 363
L I ++ D G Y C A+N G+ + V V+G P SP +A
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVA 899
Score = 48.8 bits (111), Expect = 4e-05
Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 126 ETTRRITSEQHGNTN-FRMIFQDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRH 183
E + RI +G+ + + +DAGDY C ++ ++ ++ + PP + P
Sbjct: 4391 EISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETV 4450
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLNDSSS 216
+ A GG +L C+A G P PT+TW R S S
Sbjct: 4451 INA--GGKIILNCQATGEPQPTITWSRQGHSIS 4481
>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-268N14 on chromosome 1. ).
Length = 5635
Score = 98.3 bits (234), Expect = 5e-20
Identities = 61/215 (28%), Positives = 97/215 (45%), Gaps = 15/215 (6%)
Query: 146 QDAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C + + ++ + + VLVPP + V + + L C GNPVP
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509
Query: 205 TVTWHR----LNDSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TWH+ L + + + G LQ++ ++ H G Y C + G F L V
Sbjct: 2510 EITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHK-SRSFSLNVF 2568
Query: 259 YPPEITVERSWVHTGE-----GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
P I S + + LVC + PPA ++W+++ PL ++ + + G
Sbjct: 2569 VSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGG 2628
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
TL I + Q ++ G YSCVA N G +H EV
Sbjct: 2629 --RTLQILNAQEDNAGRYSCVATNEAGEMIKHYEV 2661
Score = 96.3 bits (229), Expect = 2e-19
Identities = 66/222 (29%), Positives = 100/222 (45%), Gaps = 15/222 (6%)
Query: 146 QDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
QD G Y C+ ++ + ++ + V + VPP++ S E +T G L C ++G P P
Sbjct: 2167 QDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPP 2226
Query: 205 TVTWHR-----LNDSSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
+ W + L DS R L G QLQ+S E+ +Y+C N G E+ LQ
Sbjct: 2227 NLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT-AKKEYNLQ 2285
Query: 257 VLYPPEITVERSW---VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
V P IT S + G L C V PP V+W ++ PL ++ V + G
Sbjct: 2286 VYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEG 2345
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
H L + ++ D G Y CVA N G + ++S P+
Sbjct: 2346 --HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPS 2385
Score = 91.9 bits (218), Expect = 5e-18
Identities = 57/214 (26%), Positives = 95/214 (44%), Gaps = 9/214 (4%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
+ + +DAG Y C ++ Q H + V PPS+ + + + T LEC+AAG
Sbjct: 1887 KTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAG 1946
Query: 201 NPVPTVTWHR----LNDSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
NPVP +TW++ L+ S+S L G + + + G+Y C N G + +
Sbjct: 1947 NPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELF-YS 2005
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
LQV P I+ + V L C P ++W ++ P+S+ +
Sbjct: 2006 LQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSG 2064
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
L + Q D G Y+CVA N+ G +R +++
Sbjct: 2065 GRILALTSAQISDTGRYTCVAVNAAGEKQRDIDL 2098
Score = 87.8 bits (208), Expect = 8e-17
Identities = 67/211 (31%), Positives = 92/211 (43%), Gaps = 17/211 (8%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G YVC+ + RD + + V VPPS+ PE + L C A G P PT
Sbjct: 3124 DTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG-PEREVIVETISNPVTLTCDATGIPPPT 3182
Query: 206 VTW----HRLNDSSSR----LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W R+ +S S L G +LQ++R + G Y C N G F L +
Sbjct: 3183 IAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYF-LSI 3241
Query: 258 LYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA--SERVTMSARG 313
PP + S V G ELVC P + W ++ P+++ +ER+ +SA G
Sbjct: 3242 QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG 3301
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
S TL I D G Y+CVA N G R
Sbjct: 3302 S--TLNIYGALTSDTGKYTCVATNPAGEEDR 3330
Score = 87.4 bits (207), Expect = 1e-16
Identities = 59/203 (29%), Positives = 88/203 (43%), Gaps = 12/203 (5%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D Y C S+R D H ++V PP++ S T +T +G + + C G P P+
Sbjct: 3407 DVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPS 3466
Query: 206 VTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W R L+ + G LQL + E G Y C N G V F L+VL
Sbjct: 3467 MAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG-EVSKHFILKVLE 3525
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + E + EL C P +++W ++ PL +++V G
Sbjct: 3526 PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQV--QTLGGGEV 3583
Query: 318 LLIADVQPEDFGNYSCVADNSLG 340
L I+ Q ED G Y+C+A + G
Sbjct: 3584 LRISTAQVEDTGRYTCLASSPAG 3606
Score = 86.6 bits (205), Expect = 2e-16
Identities = 73/280 (26%), Positives = 117/280 (41%), Gaps = 22/280 (7%)
Query: 91 VGPQIRYTVD-VTIYENSETSVALAILGATGHTNVWETTR--------RITSEQHGNTNF 141
V P+IR T T+ ENS+ + G W+ + T+E +G
Sbjct: 4167 VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELIL 4226
Query: 142 R-MIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ +D+G Y C +++ A + HTV + V + V+ +G L C+A G
Sbjct: 4227 ENVVLEDSGFYTC-VANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATG 4285
Query: 201 NPVPTVTWHRLND----SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P+P +TW N+ + +L + R+ + G Y CT +N VG F +
Sbjct: 4286 IPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGF-VY 4344
Query: 257 VLYPPEITVE--RSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP + +W+ G A L C V DP + W + + S R+ GS
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGG-NAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGS 4403
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
L I ED G+Y+CVA N G R + ++ + P
Sbjct: 4404 ---LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 86.2 bits (204), Expect = 2e-16
Identities = 54/217 (24%), Positives = 96/217 (44%), Gaps = 10/217 (4%)
Query: 147 DAGDYVCQISDRVARDQV-HTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C + ++ + V+VLVPP++ ET + L+C G+P PT
Sbjct: 1706 DRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPT 1765
Query: 206 VTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W + D L G +L +++ + + G+Y C N G EF++ V
Sbjct: 1766 IMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH-KKEFEVTVHV 1824
Query: 260 PPEITVERSWVHTGEGFR-AELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP I ++ L C P ++W ++ P++ ++ + + S L
Sbjct: 1825 PPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKIQSSGRVL 1883
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
IA ED G Y+CVA N+ G ++H+++ P+
Sbjct: 1884 QIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPS 1920
Score = 86.2 bits (204), Expect = 2e-16
Identities = 61/219 (27%), Positives = 96/219 (43%), Gaps = 11/219 (5%)
Query: 147 DAGDYVC-QISDRVARDQVHTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNPV 203
D G+Y C I+ + ++ V VPPS++ S V R G + LEC + P
Sbjct: 3029 DGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPP 3088
Query: 204 PTVTWHR----LNDSS--SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P +TW++ + +S+ L +G L + + E G Y C N G F L V
Sbjct: 3089 PVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDD-KNFHLNV 3147
Query: 258 LYPPEIT-VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP I ER + L C PP ++W +N + S+ + +
Sbjct: 3148 YVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGS 3207
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L IA Q D GNY+C+A N G+A+++ +S + P+
Sbjct: 3208 KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPS 3246
Score = 84.6 bits (200), Expect = 7e-16
Identities = 62/214 (28%), Positives = 93/214 (43%), Gaps = 13/214 (6%)
Query: 142 RMIFQDAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
R+ +D+G YVC + V + + V V PP + + + GG A+L C G
Sbjct: 4317 RVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL-GGNAILNCEVKG 4375
Query: 201 NPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
+P PT+ W+R ++ +LG G L + G Y C N G V
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQLGNG-SLAIYGTVNEDAGDYTCVATNEAG-VVERSMS 4433
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
L + PP IT+E G + L C +P ++W + +S +RV + S
Sbjct: 4434 LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL---S 4490
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
N++L IAD Q ED + CVA N +G V V
Sbjct: 4491 NNSLYIADAQKEDTSEFECVARNLMGSVLVRVPV 4524
Score = 82.6 bits (195), Expect = 3e-15
Identities = 57/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 128 TRRITSEQHGNTN--FRMIFQDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHV 184
T RI +G+T + + D G Y C ++ D++ + V V P++R + +
Sbjct: 3292 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEK 3351
Query: 185 TARRGGAAV-LECRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVY 237
++ +ECRA G P P + W + L+ L G +++ R + VY
Sbjct: 3352 LMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVY 3411
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWY 295
C N G + LQV PP + ++ + +G + C P ++W
Sbjct: 3412 TCVASNRAGVDN-KHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWL 3470
Query: 296 QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
++ PL +T+S G LL A+ ED G Y+C+A N G +H
Sbjct: 3471 RDGQPLGLDAHLTVSTHGMVLQLLKAET--EDSGKYTCIASNEAGEVSKH 3518
Score = 82.2 bits (194), Expect = 4e-15
Identities = 61/210 (29%), Positives = 93/210 (44%), Gaps = 15/210 (7%)
Query: 146 QDAGDYVCQISDRVARDQV-HTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNP 202
+DAG Y C + D + + V VLVPP ++ S VT +A++EC ++G+P
Sbjct: 2841 EDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSP 2900
Query: 203 VPTVTWHR-----LNDSSSR-LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P +W + L D + L G LQ+ + G Y C +N G F L
Sbjct: 2901 APRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGS-AKKYFNLN 2959
Query: 257 VLYPPEITVERSWVHTG--EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP + +S T F L C V PP ++SW +N P+ + + G
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNF-ISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGG- 3017
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARR 344
TL I + D G Y+C+A N G +++
Sbjct: 3018 -RTLQIIRAKVSDGGEYTCIAINQAGESKK 3046
Score = 81.0 bits (191), Expect = 9e-15
Identities = 60/200 (30%), Positives = 85/200 (42%), Gaps = 13/200 (6%)
Query: 148 AGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
AG Y C + H T+ V PP ++ P HV +L C A G P P +
Sbjct: 3962 AGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNN--PILLPCEATGTPSPFI 4019
Query: 207 TWHR----LNDSSSRLGEGPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
TW + +N S P LQ+SR R G Y C N G + + +L V P
Sbjct: 4020 TWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGT-ALGKIKLNVQVP 4078
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I+ L C PP +++W+++ + S R + + GS L I
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGS---LQI 4135
Query: 321 ADVQPEDFGNYSCVADNSLG 340
A VQP D G+Y+C+A N G
Sbjct: 4136 AFVQPGDAGHYTCMAANVAG 4155
Score = 76.6 bits (180), Expect = 2e-13
Identities = 79/315 (25%), Positives = 125/315 (39%), Gaps = 31/315 (9%)
Query: 84 YNLQITDVGPQIR---YTVDVTIYENSETSVALAILGATGHTNVW-----ETTRRITSEQ 135
YNL++ V P I+ +V++ N T++ + G +W + T T +
Sbjct: 1351 YNLKV-HVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQT 1409
Query: 136 HGNTNFRMIF----QDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGG 190
N +F +DAG Y C+ + Q + ++VLVPP++ + V+
Sbjct: 1410 VNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNR 1469
Query: 191 AAVLECRAAGNPVPTVTWHR------LNDSS-SRLGEGPQLQLSRLERHHGGVYACTVDN 243
LEC+ G P P + W + L D + L G L L R+ G Y CTV N
Sbjct: 1470 DVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSN 1529
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRA--ELVCTVLADPPAEVSWYQNSFPL 301
G + +L + PP I + +L C P ++WY++ P+
Sbjct: 1530 AAGKQ-AKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPI 1588
Query: 302 SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTS 359
+S + +G L I Q D Y+C N G A + HV+V P +
Sbjct: 1589 MSSSQALYIDKG--QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLA 1646
Query: 360 PPLAR---APHSYTL 371
PL + HS TL
Sbjct: 1647 TPLNKQVVIAHSLTL 1661
Score = 76.6 bits (180), Expect = 2e-13
Identities = 60/225 (26%), Positives = 93/225 (41%), Gaps = 21/225 (9%)
Query: 149 GDYVCQISDRVA-RDQVHTVEVLVPPSVR---ASPETRHVTARRGGAAVLECRAAGNPVP 204
G Y C S + + ++ V V P++ + VT L C A P
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPA 2605
Query: 205 TVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
T+TW + N + L G LQ+ + + G Y+C N G ++ ++++V
Sbjct: 2606 TITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGE-MIKHYEVKVY 2664
Query: 259 YPPEITVERSW--------VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
PP I W V L C A P A +SWY++ PL + + V ++
Sbjct: 2665 IPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIA 2724
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
A G HTL I + Q D G Y+CVA N G +V+ + P+
Sbjct: 2725 ANG--HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPS 2767
Score = 75.8 bits (178), Expect = 3e-13
Identities = 64/227 (28%), Positives = 91/227 (40%), Gaps = 18/227 (7%)
Query: 146 QDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G Y C S D + + V V VPP++ + E R +T R LEC++ P P
Sbjct: 3592 EDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 205 TVTWHRLND---SSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TW R + ++ R L G LQ++ + Y C N G EF L V
Sbjct: 3652 VITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAG-KTTREFILTVN 3710
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNHT 317
PP I + L C P ++W ++ L+ + R ++ G H
Sbjct: 3711 VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH- 3769
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARR------HVEVSGRPGPARFT 358
I D G Y C+A N+ G RR HV S PGP T
Sbjct: 3770 --IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMT 3814
Score = 75.4 bits (177), Expect = 4e-13
Identities = 62/214 (28%), Positives = 94/214 (43%), Gaps = 18/214 (8%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTV-EVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ D G Y C + T +V PP V P +VT G AVL C
Sbjct: 488 KVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPN--NVTVTPGERAVLTCLIIS 545
Query: 201 NPVPTVTWHRLNDSSSRLGEGPQ--------LQLSRLERHHGGVYACTVDNGVGPPVVTE 252
+TW R ND RL E + L+L ++ + G Y C V + G +
Sbjct: 546 AVDYNLTWQR-NDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASV 604
Query: 253 FQLQVLYPPEITV-ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA 311
F L V PP++TV ++ TG G ++C+ P +++W N + S R M++
Sbjct: 605 F-LTVQEPPKVTVMPKNQSFTG-GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTS 662
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
G TL I + P+D G Y C+A NS G +++
Sbjct: 663 DG---TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693
Score = 73.7 bits (173), Expect = 1e-12
Identities = 60/211 (28%), Positives = 88/211 (41%), Gaps = 18/211 (8%)
Query: 147 DAGDYVCQISDRVARDQVHTVE--VLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D+G Y+C ++ +A + V+ V VPP ++ P +H+ + G + C A G P+P
Sbjct: 1144 DSGMYLC-VATNIAGNVTQAVKLNVHVPPKIQRGP--KHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 205 TVTWHRLNDSSSRLGE----GPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TW + + GE P L + + G+Y C N G TE L V
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTD-ETEITLHVQ 1259
Query: 259 YPPEI-TVERSWVHTGE----GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
PP + +E + T + R E C P + W N L+ E +S
Sbjct: 1260 EPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGRE-PGISILE 1318
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
L+IA V P D G Y CVA N G R
Sbjct: 1319 DGTLLVIASVTPYDNGEYICVAVNEAGTTER 1349
Score = 73.7 bits (173), Expect = 1e-12
Identities = 56/219 (25%), Positives = 89/219 (40%), Gaps = 13/219 (5%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C +S+ + + + +PPS++ T ++ LEC G P+P
Sbjct: 1519 DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPA 1578
Query: 206 VTWHRLND---SSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+TW++ SSS+ + +G L + R + Y C V N G F + V
Sbjct: 1579 ITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAG-TAEKSFHVDVYV 1637
Query: 260 PPEITVERSWVHTGEGFRAE---LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP I + + A L C +P ++W ++ P+ A++ + + A G
Sbjct: 1638 PPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKK- 1696
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L I Q D G Y CVA + G EV PA
Sbjct: 1697 -LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPA 1734
Score = 72.9 bits (171), Expect = 2e-12
Identities = 75/332 (22%), Positives = 123/332 (37%), Gaps = 28/332 (8%)
Query: 88 ITDVGPQIRYTVDVTIYENSETSVALAILGATGHTNVWETT---------RRITSEQHGN 138
+++ P I+ +VT+ + I+ A + W+ RI + + +
Sbjct: 516 VSEPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS 575
Query: 139 TNFRMI-FQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLEC 196
+ + F DAG+Y C +S + V PP V P+ + T G + C
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTG--GSEVSIMC 633
Query: 197 RAAGNPVPTVTWHRLNDS------SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVV 250
A G P P + W +ND R+ L + G+Y C N G
Sbjct: 634 SATGYPKPKIAW-TVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQ 692
Query: 251 TEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
L+ + P++ V +S + G + C PP +V W++ L S + +
Sbjct: 693 NS-TLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIID 751
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPP--LARAPHS 368
L I + Q D G+Y+CVA N GRA + + P P +
Sbjct: 752 PLLG--LLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSN 809
Query: 369 YTLSFAVDSYPPLDELRLLYRQLAINESFQQP 400
TL V YP E + +R+L F +P
Sbjct: 810 VTLPCYVQGYP---EPTIKWRRLDNMPIFSRP 838
Score = 71.7 bits (168), Expect = 5e-12
Identities = 60/213 (28%), Positives = 90/213 (42%), Gaps = 16/213 (7%)
Query: 147 DAGDYVCQISDRVARDQVHT---VEVLVPPSVRASPETRHVTARRGGAAVLECRA-AGNP 202
D G Y+C+ ++ + Q T V LV P + SP +V G L C AGNP
Sbjct: 861 DKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVI--EGQQLTLPCTLLAGNP 918
Query: 203 VPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPP-VVTEFQLQ 256
+P W + L + + L + R++ GG Y C N G T +
Sbjct: 919 IPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH 978
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
VL P I + + T EG L C +P V W + +S S SA G++
Sbjct: 979 VL--PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSS-AKFSA-GADG 1034
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+L + E+ G Y C A N+ G A+R V+++
Sbjct: 1035 SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLT 1067
Score = 71.3 bits (167), Expect = 7e-12
Identities = 75/306 (24%), Positives = 120/306 (39%), Gaps = 31/306 (10%)
Query: 100 DVTIYENSETSVALAILGATGHTNVWETTRRITSEQHGNTNFRMI-----------FQDA 148
++T+ N +T++A G + W + + ++R++ D
Sbjct: 3812 NMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 3871
Query: 149 GDYVCQISDRVARDQVHTVE--VLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
Y C +++ A D TV+ V VPPS+ P VT + AV+ C A+G P P++
Sbjct: 3872 ATYECTVTNG-AGDDKRTVDLTVQVPPSIADEPTDFLVT--KHAPAVITCTASGVPFPSI 3928
Query: 207 TWHRLNDSSSRLGEGPQL------QLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
W + G+G ++ ++ + +H G Y C N G L V P
Sbjct: 3929 HWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGS-AHRHVTLHVHEP 3987
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I + S +H L C P ++W + ++ S R A + L I
Sbjct: 3988 PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGR--NHAVLPSGGLQI 4045
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR----APHSYTLSFAVD 376
+ ED G Y CVA N G A ++++ + P SP L TLS D
Sbjct: 4046 SRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPV--ISPHLKEYVIAVDKPITLSCEAD 4103
Query: 377 SYPPLD 382
PP D
Sbjct: 4104 GLPPPD 4109
Score = 70.9 bits (166), Expect = 1e-11
Identities = 58/209 (27%), Positives = 86/209 (41%), Gaps = 14/209 (6%)
Query: 147 DAGDYVCQISDRVAR-DQVHTVEVLVPPSVRAS-PETRHVTARRGGAAVLECRAAGNPVP 204
DA Y C S+ + + ++V + P++ S + RG + LEC G P P
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 205 TVTW----HRLNDSS--SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
TVTW H L + L EG LQL + G Y C N G ++ L V
Sbjct: 2323 TVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG-MTDKKYDLSVH 2381
Query: 259 YPPEITVER---SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
PP I + E L C P ++W+++ +P+S S V + + G
Sbjct: 2382 APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGG-- 2439
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARR 344
L + ED G Y+CV N+ G R+
Sbjct: 2440 RMLRLMQTTMEDAGQYTCVVRNAAGEERK 2468
Score = 70.9 bits (166), Expect = 1e-11
Identities = 61/210 (29%), Positives = 86/210 (40%), Gaps = 16/210 (7%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C ++ D+ ++V VPPS+ P ++T L C A G P P+
Sbjct: 3777 DTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPT--NMTVIVNVQTTLACEATGIPKPS 3834
Query: 206 VTW----HRLN----DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W H LN +S RL L + Y CTV NG G T L V
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRT-VDLTV 3893
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL-SASERVTMSARGSNH 316
PP I E + + A + CT P + W +N L + + + G+
Sbjct: 3894 QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGA-- 3951
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHV 346
+ I Q G Y+CVA N+ G A RHV
Sbjct: 3952 -IEILATQLNHAGRYTCVARNAAGSAHRHV 3980
Score = 69.7 bits (163), Expect = 2e-11
Identities = 56/201 (27%), Positives = 83/201 (41%), Gaps = 14/201 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
DAG Y C ++ T + V VPP +R++ H T A+L C A G P P
Sbjct: 4142 DAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG--HYTVNENSQAILPCVADGIPTPA 4199
Query: 206 VTWHRLND-SSSRLGEGP-----QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W + N ++ LG+ +L L + G Y C +N G T L V
Sbjct: 4200 INWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHT-VSLTVHV 4258
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
P T V +G + L C P +++W N+ + A + + L+
Sbjct: 4259 LPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAH----FDSVNGHSELV 4314
Query: 320 IADVQPEDFGNYSCVADNSLG 340
I V ED G Y C A+NS+G
Sbjct: 4315 IERVSKEDSGTYVCTAENSVG 4335
Score = 69.3 bits (162), Expect = 3e-11
Identities = 54/223 (24%), Positives = 90/223 (40%), Gaps = 14/223 (6%)
Query: 147 DAGDYVC---QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D +Y C I+ + R+ + TV V PP+++ P++ + + + VLEC A G P
Sbjct: 3686 DTANYTCVASNIAGKTTREFILTVNV--PPNIKGGPQSLVILLNK--STVLECIAEGVPT 3741
Query: 204 PTVTWHR----LNDSSSRLG--EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P +TW + L + +R E L + G Y C N G LQV
Sbjct: 3742 PRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDR-RRIDLQV 3800
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + + + L C P ++W +N L+ + S+ +
Sbjct: 3801 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS 3860
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
L+I +D Y C N G +R V+++ + P+ P
Sbjct: 3861 LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEP 3903
Score = 68.9 bits (161), Expect = 4e-11
Identities = 52/213 (24%), Positives = 94/213 (44%), Gaps = 13/213 (6%)
Query: 147 DAGDYVC-QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G+Y+C +++ ++ + ++V VPP ++ + +V+ L C G P P
Sbjct: 1332 DNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPI 1391
Query: 206 VTWHRLN----DSSS--RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W++ N +SS+ + G L+L R G Y+C N G F + VL
Sbjct: 1392 IMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTS-QKYFNIDVLV 1450
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNH 316
PP I T + V L C V P ++ W+++ PL + V + RG
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG--Q 1508
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
L + + + D G Y C N+ G+ + ++++
Sbjct: 1509 VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 1541
Score = 68.1 bits (159), Expect = 7e-11
Identities = 55/211 (26%), Positives = 81/211 (38%), Gaps = 15/211 (7%)
Query: 147 DAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D+G+Y C S+ + Q + + + VPPSV + V+ G L C A G P P
Sbjct: 3218 DSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 206 VTWHR-----LNDSSSRL---GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W + + + R+ G L + G Y C N G F L V
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI-FNLNV 3336
Query: 258 LYPPEITV---ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
P I E + T + C PP +++W +N PL S + + A G
Sbjct: 3337 YVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG- 3395
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
+ I Q D Y+CVA N G +H
Sbjct: 3396 -QVIRIVRAQVSDVAVYTCVASNRAGVDNKH 3425
Score = 67.7 bits (158), Expect = 9e-11
Identities = 70/277 (25%), Positives = 110/277 (39%), Gaps = 41/277 (14%)
Query: 100 DVTIYENSETSVALAILGATGHTNVW-------ETTRRITSEQHGNTNFRMIFQD--AGD 150
DVT+ NS TS+ T W E+ R I G T + Q+ AG
Sbjct: 2584 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGR 2643
Query: 151 YVCQISDRVARDQVH-TVEVLVPPSVRASP------ETRHVTARRGGAAVLECRAAGNPV 203
Y C ++ H V+V +PP + + V + LEC A P
Sbjct: 2644 YSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPS 2703
Query: 204 PTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+++W++ +D + G LQ+ + G Y C N G + +F + +
Sbjct: 2704 ASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL-DFDVNI 2762
Query: 258 LYPPEITVERSW-----VHTGEGFRAE---------LVCTVLADPPAEVSWYQNSFPLSA 303
PP ++ W + TG A+ L C A PP ++WY++ PL++
Sbjct: 2763 QVPPSF--QKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS 2820
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
S++V + G L I + ED G Y+CVA N G
Sbjct: 2821 SDKVLILPGG--RVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 66.9 bits (156), Expect = 2e-10
Identities = 69/260 (26%), Positives = 107/260 (41%), Gaps = 27/260 (10%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHV--TARRGGAA--------VLE 195
D G Y C S+ D++ V + VPPS + E ++ T R G A L
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 196 CRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPV 249
C P PT+TW++ +D L G LQ+ R + G Y C N G
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Query: 250 VTEFQLQVLYPPEITVERS----WVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE 305
+ ++ ++VL PP I S V A + C P SW ++ PL +
Sbjct: 2859 L-QYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD 2917
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF--TSPPLA 363
+ G L I + Q D G Y CVA+N+ G A+++ ++ P+ S L
Sbjct: 2918 HHKFLSNG--RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLT 2975
Query: 364 RAPHSY-TLSFAVDSYPPLD 382
+++ +L+ V +PP D
Sbjct: 2976 VVVNNFISLTCEVSGFPPPD 2995
Score = 64.1 bits (149), Expect = 1e-09
Identities = 61/235 (25%), Positives = 99/235 (42%), Gaps = 21/235 (8%)
Query: 131 ITSEQHGNTNF-RMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRG 189
IT G+ + R+ QD G+Y C ++ VA T V+V + ++ G
Sbjct: 937 ITVRSDGSLHIERVQLQDGGEYTC-VASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEG 995
Query: 190 GAAVLECRAAGNPVPTVTWHR----LNDSSSRLGEGPQLQLSRLER--HHGGVYACTVDN 243
L C+A+GNP P+V W + ++ SS++ G L + G Y CT N
Sbjct: 996 IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGE--------GFRAELVCTVLADPPAEVSWY 295
G + QL V P + ++ + + G L C V + PP ++W
Sbjct: 1056 TAGY-AKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 1114
Query: 296 QNSFPLSA-SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+ + +S S R T GS + I + + D G Y CVA N G + V+++
Sbjct: 1115 KETQLISPFSPRHTFLPSGS---MKITETRTSDSGMYLCVATNIAGNVTQAVKLN 1166
Score = 60.1 bits (139), Expect = 2e-08
Identities = 60/248 (24%), Positives = 95/248 (38%), Gaps = 17/248 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C + Q + V VPP++ E ++V+ A L C++ P PT
Sbjct: 2077 DTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMG--EEQNVSVLISQAVELLCQSDAIPPPT 2134
Query: 206 VTWHR-----LNDSSSRLGEGPQ-LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+TW + L + E L++ + G Y C N G + + +
Sbjct: 2135 LTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK-TEKNYNVNIWV 2193
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + E + + EG L+C PP + W + P+ +
Sbjct: 2194 PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQ 2253
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTSPP---LARAPHSYTLS 372
L I+ + D YSCVA N G A++ +++V RP S P + S +L
Sbjct: 2254 LQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLE 2313
Query: 373 FAVDSYPP 380
V PP
Sbjct: 2314 CEVQGIPP 2321
Score = 58.0 bits (134), Expect = 7e-08
Identities = 61/229 (26%), Positives = 92/229 (40%), Gaps = 14/229 (6%)
Query: 146 QDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C S+ D Q T+ + P + V G V+EC+ +G P P
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVAL--GDITVMECKTSGIPPP 731
Query: 205 TVTWHRLN---DSSSRLGEGPQLQLSRLERHH---GGVYACTVDNGVGPPVVTEFQLQVL 258
V W + + S+ L P L L +++ G Y C N G + L V
Sbjct: 732 QVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGR-ATGKITLDVG 790
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ-NSFPL-SASERVTMSARGSNH 316
PP E + V G L C V P + W + ++ P+ S V+ ++
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRH--VEVSGRPGPARFTSPPLA 363
L I ++ D G Y C A+N G+ + V V+G P SP +A
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVA 899
Score = 48.8 bits (111), Expect = 4e-05
Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 126 ETTRRITSEQHGNTN-FRMIFQDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRH 183
E + RI +G+ + + +DAGDY C ++ ++ ++ + PP + P
Sbjct: 4391 EISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETV 4450
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLNDSSS 216
+ A GG +L C+A G P PT+TW R S S
Sbjct: 4451 INA--GGKIILNCQATGEPQPTITWSRQGHSIS 4481
>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-77J13 on chromosome 1. ).
Length = 5635
Score = 98.3 bits (234), Expect = 5e-20
Identities = 61/215 (28%), Positives = 97/215 (45%), Gaps = 15/215 (6%)
Query: 146 QDAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C + + ++ + + VLVPP + V + + L C GNPVP
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509
Query: 205 TVTWHR----LNDSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TWH+ L + + + G LQ++ ++ H G Y C + G F L V
Sbjct: 2510 EITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHK-SRSFSLNVF 2568
Query: 259 YPPEITVERSWVHTGE-----GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
P I S + + LVC + PPA ++W+++ PL ++ + + G
Sbjct: 2569 VSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGG 2628
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
TL I + Q ++ G YSCVA N G +H EV
Sbjct: 2629 --RTLQILNAQEDNAGRYSCVATNEAGEMIKHYEV 2661
Score = 96.3 bits (229), Expect = 2e-19
Identities = 66/222 (29%), Positives = 100/222 (45%), Gaps = 15/222 (6%)
Query: 146 QDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
QD G Y C+ ++ + ++ + V + VPP++ S E +T G L C ++G P P
Sbjct: 2167 QDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPP 2226
Query: 205 TVTWHR-----LNDSSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
+ W + L DS R L G QLQ+S E+ +Y+C N G E+ LQ
Sbjct: 2227 NLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT-AKKEYNLQ 2285
Query: 257 VLYPPEITVERSW---VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
V P IT S + G L C V PP V+W ++ PL ++ V + G
Sbjct: 2286 VYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEG 2345
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
H L + ++ D G Y CVA N G + ++S P+
Sbjct: 2346 --HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPS 2385
Score = 91.9 bits (218), Expect = 5e-18
Identities = 57/214 (26%), Positives = 95/214 (44%), Gaps = 9/214 (4%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
+ + +DAG Y C ++ Q H + V PPS+ + + + T LEC+AAG
Sbjct: 1887 KTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAG 1946
Query: 201 NPVPTVTWHR----LNDSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
NPVP +TW++ L+ S+S L G + + + G+Y C N G + +
Sbjct: 1947 NPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELF-YS 2005
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
LQV P I+ + V L C P ++W ++ P+S+ +
Sbjct: 2006 LQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSG 2064
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
L + Q D G Y+CVA N+ G +R +++
Sbjct: 2065 GRILALTSAQISDTGRYTCVAVNAAGEKQRDIDL 2098
Score = 87.8 bits (208), Expect = 8e-17
Identities = 67/211 (31%), Positives = 92/211 (43%), Gaps = 17/211 (8%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G YVC+ + RD + + V VPPS+ PE + L C A G P PT
Sbjct: 3124 DTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG-PEREVIVETISNPVTLTCDATGIPPPT 3182
Query: 206 VTW----HRLNDSSSR----LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W R+ +S S L G +LQ++R + G Y C N G F L +
Sbjct: 3183 IAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYF-LSI 3241
Query: 258 LYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA--SERVTMSARG 313
PP + S V G ELVC P + W ++ P+++ +ER+ +SA G
Sbjct: 3242 QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG 3301
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
S TL I D G Y+CVA N G R
Sbjct: 3302 S--TLNIYGALTSDTGKYTCVATNPAGEEDR 3330
Score = 87.4 bits (207), Expect = 1e-16
Identities = 59/203 (29%), Positives = 88/203 (43%), Gaps = 12/203 (5%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D Y C S+R D H ++V PP++ S T +T +G + + C G P P+
Sbjct: 3407 DVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPS 3466
Query: 206 VTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W R L+ + G LQL + E G Y C N G V F L+VL
Sbjct: 3467 MAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG-EVSKHFILKVLE 3525
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + E + EL C P +++W ++ PL +++V G
Sbjct: 3526 PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQV--QTLGGGEV 3583
Query: 318 LLIADVQPEDFGNYSCVADNSLG 340
L I+ Q ED G Y+C+A + G
Sbjct: 3584 LRISTAQVEDTGRYTCLASSPAG 3606
Score = 86.6 bits (205), Expect = 2e-16
Identities = 73/280 (26%), Positives = 117/280 (41%), Gaps = 22/280 (7%)
Query: 91 VGPQIRYTVD-VTIYENSETSVALAILGATGHTNVWETTR--------RITSEQHGNTNF 141
V P+IR T T+ ENS+ + G W+ + T+E +G
Sbjct: 4167 VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELIL 4226
Query: 142 R-MIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ +D+G Y C +++ A + HTV + V + V+ +G L C+A G
Sbjct: 4227 ENVVLEDSGFYTC-VANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATG 4285
Query: 201 NPVPTVTWHRLND----SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P+P +TW N+ + +L + R+ + G Y CT +N VG F +
Sbjct: 4286 IPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGF-VY 4344
Query: 257 VLYPPEITVE--RSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP + +W+ G A L C V DP + W + + S R+ GS
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGG-NAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGS 4403
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
L I ED G+Y+CVA N G R + ++ + P
Sbjct: 4404 ---LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 86.2 bits (204), Expect = 2e-16
Identities = 54/217 (24%), Positives = 96/217 (44%), Gaps = 10/217 (4%)
Query: 147 DAGDYVCQISDRVARDQV-HTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C + ++ + V+VLVPP++ ET + L+C G+P PT
Sbjct: 1706 DRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPT 1765
Query: 206 VTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W + D L G +L +++ + + G+Y C N G EF++ V
Sbjct: 1766 IMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH-KKEFEVTVHV 1824
Query: 260 PPEITVERSWVHTGEGFR-AELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP I ++ L C P ++W ++ P++ ++ + + S L
Sbjct: 1825 PPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKIQSSGRVL 1883
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
IA ED G Y+CVA N+ G ++H+++ P+
Sbjct: 1884 QIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPS 1920
Score = 86.2 bits (204), Expect = 2e-16
Identities = 61/219 (27%), Positives = 96/219 (43%), Gaps = 11/219 (5%)
Query: 147 DAGDYVC-QISDRVARDQVHTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNPV 203
D G+Y C I+ + ++ V VPPS++ S V R G + LEC + P
Sbjct: 3029 DGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPP 3088
Query: 204 PTVTWHR----LNDSS--SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P +TW++ + +S+ L +G L + + E G Y C N G F L V
Sbjct: 3089 PVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDD-KNFHLNV 3147
Query: 258 LYPPEIT-VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP I ER + L C PP ++W +N + S+ + +
Sbjct: 3148 YVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGS 3207
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L IA Q D GNY+C+A N G+A+++ +S + P+
Sbjct: 3208 KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPS 3246
Score = 84.6 bits (200), Expect = 7e-16
Identities = 62/214 (28%), Positives = 93/214 (43%), Gaps = 13/214 (6%)
Query: 142 RMIFQDAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
R+ +D+G YVC + V + + V V PP + + + GG A+L C G
Sbjct: 4317 RVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL-GGNAILNCEVKG 4375
Query: 201 NPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
+P PT+ W+R ++ +LG G L + G Y C N G V
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQLGNG-SLAIYGTVNEDAGDYTCVATNEAG-VVERSMS 4433
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
L + PP IT+E G + L C +P ++W + +S +RV + S
Sbjct: 4434 LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL---S 4490
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
N++L IAD Q ED + CVA N +G V V
Sbjct: 4491 NNSLYIADAQKEDTSEFECVARNLMGSVLVRVPV 4524
Score = 82.6 bits (195), Expect = 3e-15
Identities = 57/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 128 TRRITSEQHGNTN--FRMIFQDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHV 184
T RI +G+T + + D G Y C ++ D++ + V V P++R + +
Sbjct: 3292 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEK 3351
Query: 185 TARRGGAAV-LECRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVY 237
++ +ECRA G P P + W + L+ L G +++ R + VY
Sbjct: 3352 LMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVY 3411
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWY 295
C N G + LQV PP + ++ + +G + C P ++W
Sbjct: 3412 TCVASNRAGVDN-KHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWL 3470
Query: 296 QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
++ PL +T+S G LL A+ ED G Y+C+A N G +H
Sbjct: 3471 RDGQPLGLDAHLTVSTHGMVLQLLKAET--EDSGKYTCIASNEAGEVSKH 3518
Score = 82.2 bits (194), Expect = 4e-15
Identities = 61/210 (29%), Positives = 93/210 (44%), Gaps = 15/210 (7%)
Query: 146 QDAGDYVCQISDRVARDQV-HTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNP 202
+DAG Y C + D + + V VLVPP ++ S VT +A++EC ++G+P
Sbjct: 2841 EDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSP 2900
Query: 203 VPTVTWHR-----LNDSSSR-LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P +W + L D + L G LQ+ + G Y C +N G F L
Sbjct: 2901 APRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGS-AKKYFNLN 2959
Query: 257 VLYPPEITVERSWVHTG--EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP + +S T F L C V PP ++SW +N P+ + + G
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNF-ISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGG- 3017
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARR 344
TL I + D G Y+C+A N G +++
Sbjct: 3018 -RTLQIIRAKVSDGGEYTCIAINQAGESKK 3046
Score = 81.0 bits (191), Expect = 9e-15
Identities = 60/200 (30%), Positives = 85/200 (42%), Gaps = 13/200 (6%)
Query: 148 AGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
AG Y C + H T+ V PP ++ P HV +L C A G P P +
Sbjct: 3962 AGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNN--PILLPCEATGTPSPFI 4019
Query: 207 TWHR----LNDSSSRLGEGPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
TW + +N S P LQ+SR R G Y C N G + + +L V P
Sbjct: 4020 TWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGT-ALGKIKLNVQVP 4078
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I+ L C PP +++W+++ + S R + + GS L I
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGS---LQI 4135
Query: 321 ADVQPEDFGNYSCVADNSLG 340
A VQP D G+Y+C+A N G
Sbjct: 4136 AFVQPGDAGHYTCMAANVAG 4155
Score = 76.6 bits (180), Expect = 2e-13
Identities = 79/315 (25%), Positives = 125/315 (39%), Gaps = 31/315 (9%)
Query: 84 YNLQITDVGPQIR---YTVDVTIYENSETSVALAILGATGHTNVW-----ETTRRITSEQ 135
YNL++ V P I+ +V++ N T++ + G +W + T T +
Sbjct: 1351 YNLKV-HVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQT 1409
Query: 136 HGNTNFRMIF----QDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGG 190
N +F +DAG Y C+ + Q + ++VLVPP++ + V+
Sbjct: 1410 VNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNR 1469
Query: 191 AAVLECRAAGNPVPTVTWHR------LNDSS-SRLGEGPQLQLSRLERHHGGVYACTVDN 243
LEC+ G P P + W + L D + L G L L R+ G Y CTV N
Sbjct: 1470 DVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSN 1529
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRA--ELVCTVLADPPAEVSWYQNSFPL 301
G + +L + PP I + +L C P ++WY++ P+
Sbjct: 1530 AAGKQ-AKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPI 1588
Query: 302 SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTS 359
+S + +G L I Q D Y+C N G A + HV+V P +
Sbjct: 1589 MSSSQALYIDKG--QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLA 1646
Query: 360 PPLAR---APHSYTL 371
PL + HS TL
Sbjct: 1647 TPLNKQVVIAHSLTL 1661
Score = 76.6 bits (180), Expect = 2e-13
Identities = 60/225 (26%), Positives = 93/225 (41%), Gaps = 21/225 (9%)
Query: 149 GDYVCQISDRVA-RDQVHTVEVLVPPSVR---ASPETRHVTARRGGAAVLECRAAGNPVP 204
G Y C S + + ++ V V P++ + VT L C A P
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPA 2605
Query: 205 TVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
T+TW + N + L G LQ+ + + G Y+C N G ++ ++++V
Sbjct: 2606 TITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGE-MIKHYEVKVY 2664
Query: 259 YPPEITVERSW--------VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
PP I W V L C A P A +SWY++ PL + + V ++
Sbjct: 2665 IPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIA 2724
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
A G HTL I + Q D G Y+CVA N G +V+ + P+
Sbjct: 2725 ANG--HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPS 2767
Score = 75.8 bits (178), Expect = 3e-13
Identities = 64/227 (28%), Positives = 91/227 (40%), Gaps = 18/227 (7%)
Query: 146 QDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G Y C S D + + V V VPP++ + E R +T R LEC++ P P
Sbjct: 3592 EDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 205 TVTWHRLND---SSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TW R + ++ R L G LQ++ + Y C N G EF L V
Sbjct: 3652 VITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAG-KTTREFILTVN 3710
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNHT 317
PP I + L C P ++W ++ L+ + R ++ G H
Sbjct: 3711 VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH- 3769
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARR------HVEVSGRPGPARFT 358
I D G Y C+A N+ G RR HV S PGP T
Sbjct: 3770 --IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMT 3814
Score = 75.4 bits (177), Expect = 4e-13
Identities = 62/214 (28%), Positives = 94/214 (43%), Gaps = 18/214 (8%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTV-EVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ D G Y C + T +V PP V P +VT G AVL C
Sbjct: 488 KVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPN--NVTVTPGERAVLTCLIIS 545
Query: 201 NPVPTVTWHRLNDSSSRLGEGPQ--------LQLSRLERHHGGVYACTVDNGVGPPVVTE 252
+TW R ND RL E + L+L ++ + G Y C V + G +
Sbjct: 546 AVDYNLTWQR-NDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASV 604
Query: 253 FQLQVLYPPEITV-ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA 311
F L V PP++TV ++ TG G ++C+ P +++W N + S R M++
Sbjct: 605 F-LTVQEPPKVTVMPKNQSFTG-GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTS 662
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
G TL I + P+D G Y C+A NS G +++
Sbjct: 663 DG---TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693
Score = 73.7 bits (173), Expect = 1e-12
Identities = 60/211 (28%), Positives = 88/211 (41%), Gaps = 18/211 (8%)
Query: 147 DAGDYVCQISDRVARDQVHTVE--VLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D+G Y+C ++ +A + V+ V VPP ++ P +H+ + G + C A G P+P
Sbjct: 1144 DSGMYLC-VATNIAGNVTQAVKLNVHVPPKIQRGP--KHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 205 TVTWHRLNDSSSRLGE----GPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TW + + GE P L + + G+Y C N G TE L V
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTD-ETEITLHVQ 1259
Query: 259 YPPEI-TVERSWVHTGE----GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
PP + +E + T + R E C P + W N L+ E +S
Sbjct: 1260 EPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGRE-PGISILE 1318
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
L+IA V P D G Y CVA N G R
Sbjct: 1319 DGTLLVIASVTPYDNGEYICVAVNEAGTTER 1349
Score = 73.7 bits (173), Expect = 1e-12
Identities = 56/219 (25%), Positives = 89/219 (40%), Gaps = 13/219 (5%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C +S+ + + + +PPS++ T ++ LEC G P+P
Sbjct: 1519 DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPA 1578
Query: 206 VTWHRLND---SSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+TW++ SSS+ + +G L + R + Y C V N G F + V
Sbjct: 1579 ITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAG-TAEKSFHVDVYV 1637
Query: 260 PPEITVERSWVHTGEGFRAE---LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP I + + A L C +P ++W ++ P+ A++ + + A G
Sbjct: 1638 PPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKK- 1696
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L I Q D G Y CVA + G EV PA
Sbjct: 1697 -LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPA 1734
Score = 72.9 bits (171), Expect = 2e-12
Identities = 75/332 (22%), Positives = 123/332 (37%), Gaps = 28/332 (8%)
Query: 88 ITDVGPQIRYTVDVTIYENSETSVALAILGATGHTNVWETT---------RRITSEQHGN 138
+++ P I+ +VT+ + I+ A + W+ RI + + +
Sbjct: 516 VSEPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS 575
Query: 139 TNFRMI-FQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLEC 196
+ + F DAG+Y C +S + V PP V P+ + T G + C
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTG--GSEVSIMC 633
Query: 197 RAAGNPVPTVTWHRLNDS------SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVV 250
A G P P + W +ND R+ L + G+Y C N G
Sbjct: 634 SATGYPKPKIAW-TVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQ 692
Query: 251 TEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
L+ + P++ V +S + G + C PP +V W++ L S + +
Sbjct: 693 NS-TLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIID 751
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPP--LARAPHS 368
L I + Q D G+Y+CVA N GRA + + P P +
Sbjct: 752 PLLG--LLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSN 809
Query: 369 YTLSFAVDSYPPLDELRLLYRQLAINESFQQP 400
TL V YP E + +R+L F +P
Sbjct: 810 VTLPCYVQGYP---EPTIKWRRLDNMPIFSRP 838
Score = 71.7 bits (168), Expect = 5e-12
Identities = 60/213 (28%), Positives = 90/213 (42%), Gaps = 16/213 (7%)
Query: 147 DAGDYVCQISDRVARDQVHT---VEVLVPPSVRASPETRHVTARRGGAAVLECRA-AGNP 202
D G Y+C+ ++ + Q T V LV P + SP +V G L C AGNP
Sbjct: 861 DKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVI--EGQQLTLPCTLLAGNP 918
Query: 203 VPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPP-VVTEFQLQ 256
+P W + L + + L + R++ GG Y C N G T +
Sbjct: 919 IPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH 978
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
VL P I + + T EG L C +P V W + +S S SA G++
Sbjct: 979 VL--PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSS-AKFSA-GADG 1034
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+L + E+ G Y C A N+ G A+R V+++
Sbjct: 1035 SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLT 1067
Score = 71.3 bits (167), Expect = 7e-12
Identities = 75/306 (24%), Positives = 120/306 (39%), Gaps = 31/306 (10%)
Query: 100 DVTIYENSETSVALAILGATGHTNVWETTRRITSEQHGNTNFRMI-----------FQDA 148
++T+ N +T++A G + W + + ++R++ D
Sbjct: 3812 NMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 3871
Query: 149 GDYVCQISDRVARDQVHTVE--VLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
Y C +++ A D TV+ V VPPS+ P VT + AV+ C A+G P P++
Sbjct: 3872 ATYECTVTNG-AGDDKRTVDLTVQVPPSIADEPTDFLVT--KHAPAVITCTASGVPFPSI 3928
Query: 207 TWHRLNDSSSRLGEGPQL------QLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
W + G+G ++ ++ + +H G Y C N G L V P
Sbjct: 3929 HWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGS-AHRHVTLHVHEP 3987
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I + S +H L C P ++W + ++ S R A + L I
Sbjct: 3988 PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGR--NHAVLPSGGLQI 4045
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR----APHSYTLSFAVD 376
+ ED G Y CVA N G A ++++ + P SP L TLS D
Sbjct: 4046 SRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPV--ISPHLKEYVIAVDKPITLSCEAD 4103
Query: 377 SYPPLD 382
PP D
Sbjct: 4104 GLPPPD 4109
Score = 70.9 bits (166), Expect = 1e-11
Identities = 58/209 (27%), Positives = 86/209 (41%), Gaps = 14/209 (6%)
Query: 147 DAGDYVCQISDRVAR-DQVHTVEVLVPPSVRAS-PETRHVTARRGGAAVLECRAAGNPVP 204
DA Y C S+ + + ++V + P++ S + RG + LEC G P P
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 205 TVTW----HRLNDSS--SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
TVTW H L + L EG LQL + G Y C N G ++ L V
Sbjct: 2323 TVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG-MTDKKYDLSVH 2381
Query: 259 YPPEITVER---SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
PP I + E L C P ++W+++ +P+S S V + + G
Sbjct: 2382 APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGG-- 2439
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARR 344
L + ED G Y+CV N+ G R+
Sbjct: 2440 RMLRLMQTTMEDAGQYTCVVRNAAGEERK 2468
Score = 70.9 bits (166), Expect = 1e-11
Identities = 61/210 (29%), Positives = 86/210 (40%), Gaps = 16/210 (7%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C ++ D+ ++V VPPS+ P ++T L C A G P P+
Sbjct: 3777 DTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPT--NMTVIVNVQTTLACEATGIPKPS 3834
Query: 206 VTW----HRLN----DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W H LN +S RL L + Y CTV NG G T L V
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRT-VDLTV 3893
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL-SASERVTMSARGSNH 316
PP I E + + A + CT P + W +N L + + + G+
Sbjct: 3894 QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGA-- 3951
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHV 346
+ I Q G Y+CVA N+ G A RHV
Sbjct: 3952 -IEILATQLNHAGRYTCVARNAAGSAHRHV 3980
Score = 69.7 bits (163), Expect = 2e-11
Identities = 56/201 (27%), Positives = 83/201 (41%), Gaps = 14/201 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
DAG Y C ++ T + V VPP +R++ H T A+L C A G P P
Sbjct: 4142 DAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG--HYTVNENSQAILPCVADGIPTPA 4199
Query: 206 VTWHRLND-SSSRLGEGP-----QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W + N ++ LG+ +L L + G Y C +N G T L V
Sbjct: 4200 INWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHT-VSLTVHV 4258
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
P T V +G + L C P +++W N+ + A + + L+
Sbjct: 4259 LPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAH----FDSVNGHSELV 4314
Query: 320 IADVQPEDFGNYSCVADNSLG 340
I V ED G Y C A+NS+G
Sbjct: 4315 IERVSKEDSGTYVCTAENSVG 4335
Score = 69.3 bits (162), Expect = 3e-11
Identities = 54/223 (24%), Positives = 90/223 (40%), Gaps = 14/223 (6%)
Query: 147 DAGDYVC---QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D +Y C I+ + R+ + TV V PP+++ P++ + + + VLEC A G P
Sbjct: 3686 DTANYTCVASNIAGKTTREFILTVNV--PPNIKGGPQSLVILLNK--STVLECIAEGVPT 3741
Query: 204 PTVTWHR----LNDSSSRLG--EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P +TW + L + +R E L + G Y C N G LQV
Sbjct: 3742 PRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDR-RRIDLQV 3800
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + + + L C P ++W +N L+ + S+ +
Sbjct: 3801 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS 3860
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
L+I +D Y C N G +R V+++ + P+ P
Sbjct: 3861 LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEP 3903
Score = 68.9 bits (161), Expect = 4e-11
Identities = 52/213 (24%), Positives = 94/213 (44%), Gaps = 13/213 (6%)
Query: 147 DAGDYVC-QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G+Y+C +++ ++ + ++V VPP ++ + +V+ L C G P P
Sbjct: 1332 DNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPI 1391
Query: 206 VTWHRLN----DSSS--RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W++ N +SS+ + G L+L R G Y+C N G F + VL
Sbjct: 1392 IMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTS-QKYFNIDVLV 1450
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNH 316
PP I T + V L C V P ++ W+++ PL + V + RG
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG--Q 1508
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
L + + + D G Y C N+ G+ + ++++
Sbjct: 1509 VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 1541
Score = 68.1 bits (159), Expect = 7e-11
Identities = 55/211 (26%), Positives = 81/211 (38%), Gaps = 15/211 (7%)
Query: 147 DAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D+G+Y C S+ + Q + + + VPPSV + V+ G L C A G P P
Sbjct: 3218 DSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 206 VTWHR-----LNDSSSRL---GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W + + + R+ G L + G Y C N G F L V
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI-FNLNV 3336
Query: 258 LYPPEITV---ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
P I E + T + C PP +++W +N PL S + + A G
Sbjct: 3337 YVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG- 3395
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
+ I Q D Y+CVA N G +H
Sbjct: 3396 -QVIRIVRAQVSDVAVYTCVASNRAGVDNKH 3425
Score = 67.7 bits (158), Expect = 9e-11
Identities = 70/277 (25%), Positives = 110/277 (39%), Gaps = 41/277 (14%)
Query: 100 DVTIYENSETSVALAILGATGHTNVW-------ETTRRITSEQHGNTNFRMIFQD--AGD 150
DVT+ NS TS+ T W E+ R I G T + Q+ AG
Sbjct: 2584 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGR 2643
Query: 151 YVCQISDRVARDQVH-TVEVLVPPSVRASP------ETRHVTARRGGAAVLECRAAGNPV 203
Y C ++ H V+V +PP + + V + LEC A P
Sbjct: 2644 YSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPS 2703
Query: 204 PTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+++W++ +D + G LQ+ + G Y C N G + +F + +
Sbjct: 2704 ASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL-DFDVNI 2762
Query: 258 LYPPEITVERSW-----VHTGEGFRAE---------LVCTVLADPPAEVSWYQNSFPLSA 303
PP ++ W + TG A+ L C A PP ++WY++ PL++
Sbjct: 2763 QVPPSF--QKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS 2820
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
S++V + G L I + ED G Y+CVA N G
Sbjct: 2821 SDKVLILPGG--RVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 66.9 bits (156), Expect = 2e-10
Identities = 69/260 (26%), Positives = 107/260 (41%), Gaps = 27/260 (10%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHV--TARRGGAA--------VLE 195
D G Y C S+ D++ V + VPPS + E ++ T R G A L
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 196 CRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPV 249
C P PT+TW++ +D L G LQ+ R + G Y C N G
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Query: 250 VTEFQLQVLYPPEITVERS----WVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE 305
+ ++ ++VL PP I S V A + C P SW ++ PL +
Sbjct: 2859 L-QYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD 2917
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF--TSPPLA 363
+ G L I + Q D G Y CVA+N+ G A+++ ++ P+ S L
Sbjct: 2918 HHKFLSNG--RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLT 2975
Query: 364 RAPHSY-TLSFAVDSYPPLD 382
+++ +L+ V +PP D
Sbjct: 2976 VVVNNFISLTCEVSGFPPPD 2995
Score = 64.1 bits (149), Expect = 1e-09
Identities = 61/235 (25%), Positives = 99/235 (42%), Gaps = 21/235 (8%)
Query: 131 ITSEQHGNTNF-RMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRG 189
IT G+ + R+ QD G+Y C ++ VA T V+V + ++ G
Sbjct: 937 ITVRSDGSLHIERVQLQDGGEYTC-VASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEG 995
Query: 190 GAAVLECRAAGNPVPTVTWHR----LNDSSSRLGEGPQLQLSRLER--HHGGVYACTVDN 243
L C+A+GNP P+V W + ++ SS++ G L + G Y CT N
Sbjct: 996 IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGE--------GFRAELVCTVLADPPAEVSWY 295
G + QL V P + ++ + + G L C V + PP ++W
Sbjct: 1056 TAGY-AKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 1114
Query: 296 QNSFPLSA-SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+ + +S S R T GS + I + + D G Y CVA N G + V+++
Sbjct: 1115 KETQLISPFSPRHTFLPSGS---MKITETRTSDSGMYLCVATNIAGNVTQAVKLN 1166
Score = 60.1 bits (139), Expect = 2e-08
Identities = 60/248 (24%), Positives = 95/248 (38%), Gaps = 17/248 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C + Q + V VPP++ E ++V+ A L C++ P PT
Sbjct: 2077 DTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMG--EEQNVSVLISQAVELLCQSDAIPPPT 2134
Query: 206 VTWHR-----LNDSSSRLGEGPQ-LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+TW + L + E L++ + G Y C N G + + +
Sbjct: 2135 LTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK-TEKNYNVNIWV 2193
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + E + + EG L+C PP + W + P+ +
Sbjct: 2194 PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQ 2253
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTSPP---LARAPHSYTLS 372
L I+ + D YSCVA N G A++ +++V RP S P + S +L
Sbjct: 2254 LQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLE 2313
Query: 373 FAVDSYPP 380
V PP
Sbjct: 2314 CEVQGIPP 2321
Score = 58.0 bits (134), Expect = 7e-08
Identities = 61/229 (26%), Positives = 92/229 (40%), Gaps = 14/229 (6%)
Query: 146 QDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C S+ D Q T+ + P + V G V+EC+ +G P P
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVAL--GDITVMECKTSGIPPP 731
Query: 205 TVTWHRLN---DSSSRLGEGPQLQLSRLERHH---GGVYACTVDNGVGPPVVTEFQLQVL 258
V W + + S+ L P L L +++ G Y C N G + L V
Sbjct: 732 QVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGR-ATGKITLDVG 790
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ-NSFPL-SASERVTMSARGSNH 316
PP E + V G L C V P + W + ++ P+ S V+ ++
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRH--VEVSGRPGPARFTSPPLA 363
L I ++ D G Y C A+N G+ + V V+G P SP +A
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVA 899
Score = 48.8 bits (111), Expect = 4e-05
Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 126 ETTRRITSEQHGNTN-FRMIFQDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRH 183
E + RI +G+ + + +DAGDY C ++ ++ ++ + PP + P
Sbjct: 4391 EISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETV 4450
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLNDSSS 216
+ A GG +L C+A G P PT+TW R S S
Sbjct: 4451 INA--GGKIILNCQATGEPQPTITWSRQGHSIS 4481
>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-164L12 on chromosome 1. ).
Length = 5635
Score = 98.3 bits (234), Expect = 5e-20
Identities = 61/215 (28%), Positives = 97/215 (45%), Gaps = 15/215 (6%)
Query: 146 QDAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C + + ++ + + VLVPP + V + + L C GNPVP
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509
Query: 205 TVTWHR----LNDSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TWH+ L + + + G LQ++ ++ H G Y C + G F L V
Sbjct: 2510 EITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHK-SRSFSLNVF 2568
Query: 259 YPPEITVERSWVHTGE-----GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
P I S + + LVC + PPA ++W+++ PL ++ + + G
Sbjct: 2569 VSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGG 2628
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
TL I + Q ++ G YSCVA N G +H EV
Sbjct: 2629 --RTLQILNAQEDNAGRYSCVATNEAGEMIKHYEV 2661
Score = 96.3 bits (229), Expect = 2e-19
Identities = 66/222 (29%), Positives = 100/222 (45%), Gaps = 15/222 (6%)
Query: 146 QDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
QD G Y C+ ++ + ++ + V + VPP++ S E +T G L C ++G P P
Sbjct: 2167 QDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPP 2226
Query: 205 TVTWHR-----LNDSSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
+ W + L DS R L G QLQ+S E+ +Y+C N G E+ LQ
Sbjct: 2227 NLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT-AKKEYNLQ 2285
Query: 257 VLYPPEITVERSW---VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
V P IT S + G L C V PP V+W ++ PL ++ V + G
Sbjct: 2286 VYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEG 2345
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
H L + ++ D G Y CVA N G + ++S P+
Sbjct: 2346 --HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPS 2385
Score = 91.9 bits (218), Expect = 5e-18
Identities = 57/214 (26%), Positives = 95/214 (44%), Gaps = 9/214 (4%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
+ + +DAG Y C ++ Q H + V PPS+ + + + T LEC+AAG
Sbjct: 1887 KTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAG 1946
Query: 201 NPVPTVTWHR----LNDSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
NPVP +TW++ L+ S+S L G + + + G+Y C N G + +
Sbjct: 1947 NPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELF-YS 2005
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
LQV P I+ + V L C P ++W ++ P+S+ +
Sbjct: 2006 LQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSG 2064
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
L + Q D G Y+CVA N+ G +R +++
Sbjct: 2065 GRILALTSAQISDTGRYTCVAVNAAGEKQRDIDL 2098
Score = 87.8 bits (208), Expect = 8e-17
Identities = 67/211 (31%), Positives = 92/211 (43%), Gaps = 17/211 (8%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G YVC+ + RD + + V VPPS+ PE + L C A G P PT
Sbjct: 3124 DTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG-PEREVIVETISNPVTLTCDATGIPPPT 3182
Query: 206 VTW----HRLNDSSSR----LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W R+ +S S L G +LQ++R + G Y C N G F L +
Sbjct: 3183 IAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYF-LSI 3241
Query: 258 LYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA--SERVTMSARG 313
PP + S V G ELVC P + W ++ P+++ +ER+ +SA G
Sbjct: 3242 QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG 3301
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
S TL I D G Y+CVA N G R
Sbjct: 3302 S--TLNIYGALTSDTGKYTCVATNPAGEEDR 3330
Score = 87.4 bits (207), Expect = 1e-16
Identities = 59/203 (29%), Positives = 88/203 (43%), Gaps = 12/203 (5%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D Y C S+R D H ++V PP++ S T +T +G + + C G P P+
Sbjct: 3407 DVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPS 3466
Query: 206 VTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W R L+ + G LQL + E G Y C N G V F L+VL
Sbjct: 3467 MAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG-EVSKHFILKVLE 3525
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + E + EL C P +++W ++ PL +++V G
Sbjct: 3526 PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQV--QTLGGGEV 3583
Query: 318 LLIADVQPEDFGNYSCVADNSLG 340
L I+ Q ED G Y+C+A + G
Sbjct: 3584 LRISTAQVEDTGRYTCLASSPAG 3606
Score = 86.6 bits (205), Expect = 2e-16
Identities = 73/280 (26%), Positives = 117/280 (41%), Gaps = 22/280 (7%)
Query: 91 VGPQIRYTVD-VTIYENSETSVALAILGATGHTNVWETTR--------RITSEQHGNTNF 141
V P+IR T T+ ENS+ + G W+ + T+E +G
Sbjct: 4167 VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELIL 4226
Query: 142 R-MIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ +D+G Y C +++ A + HTV + V + V+ +G L C+A G
Sbjct: 4227 ENVVLEDSGFYTC-VANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATG 4285
Query: 201 NPVPTVTWHRLND----SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P+P +TW N+ + +L + R+ + G Y CT +N VG F +
Sbjct: 4286 IPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGF-VY 4344
Query: 257 VLYPPEITVE--RSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP + +W+ G A L C V DP + W + + S R+ GS
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGG-NAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGS 4403
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
L I ED G+Y+CVA N G R + ++ + P
Sbjct: 4404 ---LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 86.2 bits (204), Expect = 2e-16
Identities = 54/217 (24%), Positives = 96/217 (44%), Gaps = 10/217 (4%)
Query: 147 DAGDYVCQISDRVARDQV-HTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C + ++ + V+VLVPP++ ET + L+C G+P PT
Sbjct: 1706 DRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPT 1765
Query: 206 VTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W + D L G +L +++ + + G+Y C N G EF++ V
Sbjct: 1766 IMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH-KKEFEVTVHV 1824
Query: 260 PPEITVERSWVHTGEGFR-AELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP I ++ L C P ++W ++ P++ ++ + + S L
Sbjct: 1825 PPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKIQSSGRVL 1883
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
IA ED G Y+CVA N+ G ++H+++ P+
Sbjct: 1884 QIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPS 1920
Score = 86.2 bits (204), Expect = 2e-16
Identities = 61/219 (27%), Positives = 96/219 (43%), Gaps = 11/219 (5%)
Query: 147 DAGDYVC-QISDRVARDQVHTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNPV 203
D G+Y C I+ + ++ V VPPS++ S V R G + LEC + P
Sbjct: 3029 DGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPP 3088
Query: 204 PTVTWHR----LNDSS--SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P +TW++ + +S+ L +G L + + E G Y C N G F L V
Sbjct: 3089 PVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDD-KNFHLNV 3147
Query: 258 LYPPEIT-VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP I ER + L C PP ++W +N + S+ + +
Sbjct: 3148 YVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGS 3207
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L IA Q D GNY+C+A N G+A+++ +S + P+
Sbjct: 3208 KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPS 3246
Score = 84.6 bits (200), Expect = 7e-16
Identities = 62/214 (28%), Positives = 93/214 (43%), Gaps = 13/214 (6%)
Query: 142 RMIFQDAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
R+ +D+G YVC + V + + V V PP + + + GG A+L C G
Sbjct: 4317 RVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL-GGNAILNCEVKG 4375
Query: 201 NPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
+P PT+ W+R ++ +LG G L + G Y C N G V
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQLGNG-SLAIYGTVNEDAGDYTCVATNEAG-VVERSMS 4433
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
L + PP IT+E G + L C +P ++W + +S +RV + S
Sbjct: 4434 LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL---S 4490
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
N++L IAD Q ED + CVA N +G V V
Sbjct: 4491 NNSLYIADAQKEDTSEFECVARNLMGSVLVRVPV 4524
Score = 82.6 bits (195), Expect = 3e-15
Identities = 57/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 128 TRRITSEQHGNTN--FRMIFQDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHV 184
T RI +G+T + + D G Y C ++ D++ + V V P++R + +
Sbjct: 3292 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEK 3351
Query: 185 TARRGGAAV-LECRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVY 237
++ +ECRA G P P + W + L+ L G +++ R + VY
Sbjct: 3352 LMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVY 3411
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWY 295
C N G + LQV PP + ++ + +G + C P ++W
Sbjct: 3412 TCVASNRAGVDN-KHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWL 3470
Query: 296 QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
++ PL +T+S G LL A+ ED G Y+C+A N G +H
Sbjct: 3471 RDGQPLGLDAHLTVSTHGMVLQLLKAET--EDSGKYTCIASNEAGEVSKH 3518
Score = 82.2 bits (194), Expect = 4e-15
Identities = 61/210 (29%), Positives = 93/210 (44%), Gaps = 15/210 (7%)
Query: 146 QDAGDYVCQISDRVARDQV-HTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNP 202
+DAG Y C + D + + V VLVPP ++ S VT +A++EC ++G+P
Sbjct: 2841 EDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSP 2900
Query: 203 VPTVTWHR-----LNDSSSR-LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P +W + L D + L G LQ+ + G Y C +N G F L
Sbjct: 2901 APRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGS-AKKYFNLN 2959
Query: 257 VLYPPEITVERSWVHTG--EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP + +S T F L C V PP ++SW +N P+ + + G
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNF-ISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGG- 3017
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARR 344
TL I + D G Y+C+A N G +++
Sbjct: 3018 -RTLQIIRAKVSDGGEYTCIAINQAGESKK 3046
Score = 81.0 bits (191), Expect = 9e-15
Identities = 60/200 (30%), Positives = 85/200 (42%), Gaps = 13/200 (6%)
Query: 148 AGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
AG Y C + H T+ V PP ++ P HV +L C A G P P +
Sbjct: 3962 AGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNN--PILLPCEATGTPSPFI 4019
Query: 207 TWHR----LNDSSSRLGEGPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
TW + +N S P LQ+SR R G Y C N G + + +L V P
Sbjct: 4020 TWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGT-ALGKIKLNVQVP 4078
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I+ L C PP +++W+++ + S R + + GS L I
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGS---LQI 4135
Query: 321 ADVQPEDFGNYSCVADNSLG 340
A VQP D G+Y+C+A N G
Sbjct: 4136 AFVQPGDAGHYTCMAANVAG 4155
Score = 76.6 bits (180), Expect = 2e-13
Identities = 79/315 (25%), Positives = 125/315 (39%), Gaps = 31/315 (9%)
Query: 84 YNLQITDVGPQIR---YTVDVTIYENSETSVALAILGATGHTNVW-----ETTRRITSEQ 135
YNL++ V P I+ +V++ N T++ + G +W + T T +
Sbjct: 1351 YNLKV-HVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQT 1409
Query: 136 HGNTNFRMIF----QDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGG 190
N +F +DAG Y C+ + Q + ++VLVPP++ + V+
Sbjct: 1410 VNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNR 1469
Query: 191 AAVLECRAAGNPVPTVTWHR------LNDSS-SRLGEGPQLQLSRLERHHGGVYACTVDN 243
LEC+ G P P + W + L D + L G L L R+ G Y CTV N
Sbjct: 1470 DVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSN 1529
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRA--ELVCTVLADPPAEVSWYQNSFPL 301
G + +L + PP I + +L C P ++WY++ P+
Sbjct: 1530 AAGKQ-AKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPI 1588
Query: 302 SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTS 359
+S + +G L I Q D Y+C N G A + HV+V P +
Sbjct: 1589 MSSSQALYIDKG--QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLA 1646
Query: 360 PPLAR---APHSYTL 371
PL + HS TL
Sbjct: 1647 TPLNKQVVIAHSLTL 1661
Score = 76.6 bits (180), Expect = 2e-13
Identities = 60/225 (26%), Positives = 93/225 (41%), Gaps = 21/225 (9%)
Query: 149 GDYVCQISDRVA-RDQVHTVEVLVPPSVR---ASPETRHVTARRGGAAVLECRAAGNPVP 204
G Y C S + + ++ V V P++ + VT L C A P
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPA 2605
Query: 205 TVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
T+TW + N + L G LQ+ + + G Y+C N G ++ ++++V
Sbjct: 2606 TITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGE-MIKHYEVKVY 2664
Query: 259 YPPEITVERSW--------VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
PP I W V L C A P A +SWY++ PL + + V ++
Sbjct: 2665 IPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIA 2724
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
A G HTL I + Q D G Y+CVA N G +V+ + P+
Sbjct: 2725 ANG--HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPS 2767
Score = 75.8 bits (178), Expect = 3e-13
Identities = 64/227 (28%), Positives = 91/227 (40%), Gaps = 18/227 (7%)
Query: 146 QDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G Y C S D + + V V VPP++ + E R +T R LEC++ P P
Sbjct: 3592 EDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 205 TVTWHRLND---SSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TW R + ++ R L G LQ++ + Y C N G EF L V
Sbjct: 3652 VITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAG-KTTREFILTVN 3710
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNHT 317
PP I + L C P ++W ++ L+ + R ++ G H
Sbjct: 3711 VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH- 3769
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARR------HVEVSGRPGPARFT 358
I D G Y C+A N+ G RR HV S PGP T
Sbjct: 3770 --IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMT 3814
Score = 75.4 bits (177), Expect = 4e-13
Identities = 62/214 (28%), Positives = 94/214 (43%), Gaps = 18/214 (8%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTV-EVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ D G Y C + T +V PP V P +VT G AVL C
Sbjct: 488 KVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPN--NVTVTPGERAVLTCLIIS 545
Query: 201 NPVPTVTWHRLNDSSSRLGEGPQ--------LQLSRLERHHGGVYACTVDNGVGPPVVTE 252
+TW R ND RL E + L+L ++ + G Y C V + G +
Sbjct: 546 AVDYNLTWQR-NDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASV 604
Query: 253 FQLQVLYPPEITV-ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA 311
F L V PP++TV ++ TG G ++C+ P +++W N + S R M++
Sbjct: 605 F-LTVQEPPKVTVMPKNQSFTG-GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTS 662
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
G TL I + P+D G Y C+A NS G +++
Sbjct: 663 DG---TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693
Score = 73.7 bits (173), Expect = 1e-12
Identities = 60/211 (28%), Positives = 88/211 (41%), Gaps = 18/211 (8%)
Query: 147 DAGDYVCQISDRVARDQVHTVE--VLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D+G Y+C ++ +A + V+ V VPP ++ P +H+ + G + C A G P+P
Sbjct: 1144 DSGMYLC-VATNIAGNVTQAVKLNVHVPPKIQRGP--KHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 205 TVTWHRLNDSSSRLGE----GPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TW + + GE P L + + G+Y C N G TE L V
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTD-ETEITLHVQ 1259
Query: 259 YPPEI-TVERSWVHTGE----GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
PP + +E + T + R E C P + W N L+ E +S
Sbjct: 1260 EPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGRE-PGISILE 1318
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
L+IA V P D G Y CVA N G R
Sbjct: 1319 DGTLLVIASVTPYDNGEYICVAVNEAGTTER 1349
Score = 73.7 bits (173), Expect = 1e-12
Identities = 56/219 (25%), Positives = 89/219 (40%), Gaps = 13/219 (5%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C +S+ + + + +PPS++ T ++ LEC G P+P
Sbjct: 1519 DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPA 1578
Query: 206 VTWHRLND---SSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+TW++ SSS+ + +G L + R + Y C V N G F + V
Sbjct: 1579 ITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAG-TAEKSFHVDVYV 1637
Query: 260 PPEITVERSWVHTGEGFRAE---LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP I + + A L C +P ++W ++ P+ A++ + + A G
Sbjct: 1638 PPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKK- 1696
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L I Q D G Y CVA + G EV PA
Sbjct: 1697 -LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPA 1734
Score = 72.9 bits (171), Expect = 2e-12
Identities = 75/332 (22%), Positives = 123/332 (37%), Gaps = 28/332 (8%)
Query: 88 ITDVGPQIRYTVDVTIYENSETSVALAILGATGHTNVWETT---------RRITSEQHGN 138
+++ P I+ +VT+ + I+ A + W+ RI + + +
Sbjct: 516 VSEPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS 575
Query: 139 TNFRMI-FQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLEC 196
+ + F DAG+Y C +S + V PP V P+ + T G + C
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTG--GSEVSIMC 633
Query: 197 RAAGNPVPTVTWHRLNDS------SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVV 250
A G P P + W +ND R+ L + G+Y C N G
Sbjct: 634 SATGYPKPKIAW-TVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQ 692
Query: 251 TEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
L+ + P++ V +S + G + C PP +V W++ L S + +
Sbjct: 693 NS-TLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIID 751
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPP--LARAPHS 368
L I + Q D G+Y+CVA N GRA + + P P +
Sbjct: 752 PLLG--LLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSN 809
Query: 369 YTLSFAVDSYPPLDELRLLYRQLAINESFQQP 400
TL V YP E + +R+L F +P
Sbjct: 810 VTLPCYVQGYP---EPTIKWRRLDNMPIFSRP 838
Score = 71.7 bits (168), Expect = 5e-12
Identities = 60/213 (28%), Positives = 90/213 (42%), Gaps = 16/213 (7%)
Query: 147 DAGDYVCQISDRVARDQVHT---VEVLVPPSVRASPETRHVTARRGGAAVLECRA-AGNP 202
D G Y+C+ ++ + Q T V LV P + SP +V G L C AGNP
Sbjct: 861 DKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVI--EGQQLTLPCTLLAGNP 918
Query: 203 VPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPP-VVTEFQLQ 256
+P W + L + + L + R++ GG Y C N G T +
Sbjct: 919 IPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH 978
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
VL P I + + T EG L C +P V W + +S S SA G++
Sbjct: 979 VL--PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSS-AKFSA-GADG 1034
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+L + E+ G Y C A N+ G A+R V+++
Sbjct: 1035 SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLT 1067
Score = 71.3 bits (167), Expect = 7e-12
Identities = 75/306 (24%), Positives = 120/306 (39%), Gaps = 31/306 (10%)
Query: 100 DVTIYENSETSVALAILGATGHTNVWETTRRITSEQHGNTNFRMI-----------FQDA 148
++T+ N +T++A G + W + + ++R++ D
Sbjct: 3812 NMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 3871
Query: 149 GDYVCQISDRVARDQVHTVE--VLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
Y C +++ A D TV+ V VPPS+ P VT + AV+ C A+G P P++
Sbjct: 3872 ATYECTVTNG-AGDDKRTVDLTVQVPPSIADEPTDFLVT--KHAPAVITCTASGVPFPSI 3928
Query: 207 TWHRLNDSSSRLGEGPQL------QLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
W + G+G ++ ++ + +H G Y C N G L V P
Sbjct: 3929 HWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGS-AHRHVTLHVHEP 3987
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I + S +H L C P ++W + ++ S R A + L I
Sbjct: 3988 PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGR--NHAVLPSGGLQI 4045
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR----APHSYTLSFAVD 376
+ ED G Y CVA N G A ++++ + P SP L TLS D
Sbjct: 4046 SRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPV--ISPHLKEYVIAVDKPITLSCEAD 4103
Query: 377 SYPPLD 382
PP D
Sbjct: 4104 GLPPPD 4109
Score = 70.9 bits (166), Expect = 1e-11
Identities = 58/209 (27%), Positives = 86/209 (41%), Gaps = 14/209 (6%)
Query: 147 DAGDYVCQISDRVAR-DQVHTVEVLVPPSVRAS-PETRHVTARRGGAAVLECRAAGNPVP 204
DA Y C S+ + + ++V + P++ S + RG + LEC G P P
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 205 TVTW----HRLNDSS--SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
TVTW H L + L EG LQL + G Y C N G ++ L V
Sbjct: 2323 TVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG-MTDKKYDLSVH 2381
Query: 259 YPPEITVER---SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
PP I + E L C P ++W+++ +P+S S V + + G
Sbjct: 2382 APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGG-- 2439
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARR 344
L + ED G Y+CV N+ G R+
Sbjct: 2440 RMLRLMQTTMEDAGQYTCVVRNAAGEERK 2468
Score = 70.9 bits (166), Expect = 1e-11
Identities = 61/210 (29%), Positives = 86/210 (40%), Gaps = 16/210 (7%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C ++ D+ ++V VPPS+ P ++T L C A G P P+
Sbjct: 3777 DTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPT--NMTVIVNVQTTLACEATGIPKPS 3834
Query: 206 VTW----HRLN----DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W H LN +S RL L + Y CTV NG G T L V
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRT-VDLTV 3893
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL-SASERVTMSARGSNH 316
PP I E + + A + CT P + W +N L + + + G+
Sbjct: 3894 QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGA-- 3951
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHV 346
+ I Q G Y+CVA N+ G A RHV
Sbjct: 3952 -IEILATQLNHAGRYTCVARNAAGSAHRHV 3980
Score = 69.7 bits (163), Expect = 2e-11
Identities = 56/201 (27%), Positives = 83/201 (41%), Gaps = 14/201 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
DAG Y C ++ T + V VPP +R++ H T A+L C A G P P
Sbjct: 4142 DAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG--HYTVNENSQAILPCVADGIPTPA 4199
Query: 206 VTWHRLND-SSSRLGEGP-----QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W + N ++ LG+ +L L + G Y C +N G T L V
Sbjct: 4200 INWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHT-VSLTVHV 4258
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
P T V +G + L C P +++W N+ + A + + L+
Sbjct: 4259 LPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAH----FDSVNGHSELV 4314
Query: 320 IADVQPEDFGNYSCVADNSLG 340
I V ED G Y C A+NS+G
Sbjct: 4315 IERVSKEDSGTYVCTAENSVG 4335
Score = 69.3 bits (162), Expect = 3e-11
Identities = 54/223 (24%), Positives = 90/223 (40%), Gaps = 14/223 (6%)
Query: 147 DAGDYVC---QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D +Y C I+ + R+ + TV V PP+++ P++ + + + VLEC A G P
Sbjct: 3686 DTANYTCVASNIAGKTTREFILTVNV--PPNIKGGPQSLVILLNK--STVLECIAEGVPT 3741
Query: 204 PTVTWHR----LNDSSSRLG--EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P +TW + L + +R E L + G Y C N G LQV
Sbjct: 3742 PRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDR-RRIDLQV 3800
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + + + L C P ++W +N L+ + S+ +
Sbjct: 3801 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS 3860
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
L+I +D Y C N G +R V+++ + P+ P
Sbjct: 3861 LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEP 3903
Score = 68.9 bits (161), Expect = 4e-11
Identities = 52/213 (24%), Positives = 94/213 (44%), Gaps = 13/213 (6%)
Query: 147 DAGDYVC-QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G+Y+C +++ ++ + ++V VPP ++ + +V+ L C G P P
Sbjct: 1332 DNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPI 1391
Query: 206 VTWHRLN----DSSS--RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W++ N +SS+ + G L+L R G Y+C N G F + VL
Sbjct: 1392 IMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTS-QKYFNIDVLV 1450
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNH 316
PP I T + V L C V P ++ W+++ PL + V + RG
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG--Q 1508
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
L + + + D G Y C N+ G+ + ++++
Sbjct: 1509 VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 1541
Score = 68.1 bits (159), Expect = 7e-11
Identities = 55/211 (26%), Positives = 81/211 (38%), Gaps = 15/211 (7%)
Query: 147 DAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D+G+Y C S+ + Q + + + VPPSV + V+ G L C A G P P
Sbjct: 3218 DSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 206 VTWHR-----LNDSSSRL---GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W + + + R+ G L + G Y C N G F L V
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI-FNLNV 3336
Query: 258 LYPPEITV---ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
P I E + T + C PP +++W +N PL S + + A G
Sbjct: 3337 YVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG- 3395
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
+ I Q D Y+CVA N G +H
Sbjct: 3396 -QVIRIVRAQVSDVAVYTCVASNRAGVDNKH 3425
Score = 67.7 bits (158), Expect = 9e-11
Identities = 70/277 (25%), Positives = 110/277 (39%), Gaps = 41/277 (14%)
Query: 100 DVTIYENSETSVALAILGATGHTNVW-------ETTRRITSEQHGNTNFRMIFQD--AGD 150
DVT+ NS TS+ T W E+ R I G T + Q+ AG
Sbjct: 2584 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGR 2643
Query: 151 YVCQISDRVARDQVH-TVEVLVPPSVRASP------ETRHVTARRGGAAVLECRAAGNPV 203
Y C ++ H V+V +PP + + V + LEC A P
Sbjct: 2644 YSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPS 2703
Query: 204 PTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+++W++ +D + G LQ+ + G Y C N G + +F + +
Sbjct: 2704 ASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL-DFDVNI 2762
Query: 258 LYPPEITVERSW-----VHTGEGFRAE---------LVCTVLADPPAEVSWYQNSFPLSA 303
PP ++ W + TG A+ L C A PP ++WY++ PL++
Sbjct: 2763 QVPPSF--QKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS 2820
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
S++V + G L I + ED G Y+CVA N G
Sbjct: 2821 SDKVLILPGG--RVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 66.9 bits (156), Expect = 2e-10
Identities = 69/260 (26%), Positives = 107/260 (41%), Gaps = 27/260 (10%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHV--TARRGGAA--------VLE 195
D G Y C S+ D++ V + VPPS + E ++ T R G A L
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 196 CRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPV 249
C P PT+TW++ +D L G LQ+ R + G Y C N G
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Query: 250 VTEFQLQVLYPPEITVERS----WVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE 305
+ ++ ++VL PP I S V A + C P SW ++ PL +
Sbjct: 2859 L-QYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD 2917
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF--TSPPLA 363
+ G L I + Q D G Y CVA+N+ G A+++ ++ P+ S L
Sbjct: 2918 HHKFLSNG--RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLT 2975
Query: 364 RAPHSY-TLSFAVDSYPPLD 382
+++ +L+ V +PP D
Sbjct: 2976 VVVNNFISLTCEVSGFPPPD 2995
Score = 64.1 bits (149), Expect = 1e-09
Identities = 61/235 (25%), Positives = 99/235 (42%), Gaps = 21/235 (8%)
Query: 131 ITSEQHGNTNF-RMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRG 189
IT G+ + R+ QD G+Y C ++ VA T V+V + ++ G
Sbjct: 937 ITVRSDGSLHIERVQLQDGGEYTC-VASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEG 995
Query: 190 GAAVLECRAAGNPVPTVTWHR----LNDSSSRLGEGPQLQLSRLER--HHGGVYACTVDN 243
L C+A+GNP P+V W + ++ SS++ G L + G Y CT N
Sbjct: 996 IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGE--------GFRAELVCTVLADPPAEVSWY 295
G + QL V P + ++ + + G L C V + PP ++W
Sbjct: 1056 TAGY-AKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 1114
Query: 296 QNSFPLSA-SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+ + +S S R T GS + I + + D G Y CVA N G + V+++
Sbjct: 1115 KETQLISPFSPRHTFLPSGS---MKITETRTSDSGMYLCVATNIAGNVTQAVKLN 1166
Score = 60.1 bits (139), Expect = 2e-08
Identities = 60/248 (24%), Positives = 95/248 (38%), Gaps = 17/248 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C + Q + V VPP++ E ++V+ A L C++ P PT
Sbjct: 2077 DTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMG--EEQNVSVLISQAVELLCQSDAIPPPT 2134
Query: 206 VTWHR-----LNDSSSRLGEGPQ-LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+TW + L + E L++ + G Y C N G + + +
Sbjct: 2135 LTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK-TEKNYNVNIWV 2193
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + E + + EG L+C PP + W + P+ +
Sbjct: 2194 PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQ 2253
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTSPP---LARAPHSYTLS 372
L I+ + D YSCVA N G A++ +++V RP S P + S +L
Sbjct: 2254 LQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLE 2313
Query: 373 FAVDSYPP 380
V PP
Sbjct: 2314 CEVQGIPP 2321
Score = 58.0 bits (134), Expect = 7e-08
Identities = 61/229 (26%), Positives = 92/229 (40%), Gaps = 14/229 (6%)
Query: 146 QDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C S+ D Q T+ + P + V G V+EC+ +G P P
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVAL--GDITVMECKTSGIPPP 731
Query: 205 TVTWHRLN---DSSSRLGEGPQLQLSRLERHH---GGVYACTVDNGVGPPVVTEFQLQVL 258
V W + + S+ L P L L +++ G Y C N G + L V
Sbjct: 732 QVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGR-ATGKITLDVG 790
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ-NSFPL-SASERVTMSARGSNH 316
PP E + V G L C V P + W + ++ P+ S V+ ++
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRH--VEVSGRPGPARFTSPPLA 363
L I ++ D G Y C A+N G+ + V V+G P SP +A
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVA 899
Score = 48.8 bits (111), Expect = 4e-05
Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 126 ETTRRITSEQHGNTN-FRMIFQDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRH 183
E + RI +G+ + + +DAGDY C ++ ++ ++ + PP + P
Sbjct: 4391 EISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETV 4450
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLNDSSS 216
+ A GG +L C+A G P PT+TW R S S
Sbjct: 4451 INA--GGKIILNCQATGEPQPTITWSRQGHSIS 4481
>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-174L6 on chromosome 1. ).
Length = 5635
Score = 98.3 bits (234), Expect = 5e-20
Identities = 61/215 (28%), Positives = 97/215 (45%), Gaps = 15/215 (6%)
Query: 146 QDAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C + + ++ + + VLVPP + V + + L C GNPVP
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509
Query: 205 TVTWHR----LNDSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TWH+ L + + + G LQ++ ++ H G Y C + G F L V
Sbjct: 2510 EITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHK-SRSFSLNVF 2568
Query: 259 YPPEITVERSWVHTGE-----GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
P I S + + LVC + PPA ++W+++ PL ++ + + G
Sbjct: 2569 VSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGG 2628
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
TL I + Q ++ G YSCVA N G +H EV
Sbjct: 2629 --RTLQILNAQEDNAGRYSCVATNEAGEMIKHYEV 2661
Score = 96.3 bits (229), Expect = 2e-19
Identities = 66/222 (29%), Positives = 100/222 (45%), Gaps = 15/222 (6%)
Query: 146 QDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
QD G Y C+ ++ + ++ + V + VPP++ S E +T G L C ++G P P
Sbjct: 2167 QDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPP 2226
Query: 205 TVTWHR-----LNDSSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
+ W + L DS R L G QLQ+S E+ +Y+C N G E+ LQ
Sbjct: 2227 NLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT-AKKEYNLQ 2285
Query: 257 VLYPPEITVERSW---VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
V P IT S + G L C V PP V+W ++ PL ++ V + G
Sbjct: 2286 VYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEG 2345
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
H L + ++ D G Y CVA N G + ++S P+
Sbjct: 2346 --HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPS 2385
Score = 91.9 bits (218), Expect = 5e-18
Identities = 57/214 (26%), Positives = 95/214 (44%), Gaps = 9/214 (4%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
+ + +DAG Y C ++ Q H + V PPS+ + + + T LEC+AAG
Sbjct: 1887 KTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAG 1946
Query: 201 NPVPTVTWHR----LNDSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
NPVP +TW++ L+ S+S L G + + + G+Y C N G + +
Sbjct: 1947 NPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELF-YS 2005
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
LQV P I+ + V L C P ++W ++ P+S+ +
Sbjct: 2006 LQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSG 2064
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
L + Q D G Y+CVA N+ G +R +++
Sbjct: 2065 GRILALTSAQISDTGRYTCVAVNAAGEKQRDIDL 2098
Score = 87.8 bits (208), Expect = 8e-17
Identities = 67/211 (31%), Positives = 92/211 (43%), Gaps = 17/211 (8%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G YVC+ + RD + + V VPPS+ PE + L C A G P PT
Sbjct: 3124 DTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG-PEREVIVETISNPVTLTCDATGIPPPT 3182
Query: 206 VTW----HRLNDSSSR----LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W R+ +S S L G +LQ++R + G Y C N G F L +
Sbjct: 3183 IAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYF-LSI 3241
Query: 258 LYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA--SERVTMSARG 313
PP + S V G ELVC P + W ++ P+++ +ER+ +SA G
Sbjct: 3242 QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG 3301
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
S TL I D G Y+CVA N G R
Sbjct: 3302 S--TLNIYGALTSDTGKYTCVATNPAGEEDR 3330
Score = 87.4 bits (207), Expect = 1e-16
Identities = 59/203 (29%), Positives = 88/203 (43%), Gaps = 12/203 (5%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D Y C S+R D H ++V PP++ S T +T +G + + C G P P+
Sbjct: 3407 DVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPS 3466
Query: 206 VTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W R L+ + G LQL + E G Y C N G V F L+VL
Sbjct: 3467 MAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG-EVSKHFILKVLE 3525
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + E + EL C P +++W ++ PL +++V G
Sbjct: 3526 PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQV--QTLGGGEV 3583
Query: 318 LLIADVQPEDFGNYSCVADNSLG 340
L I+ Q ED G Y+C+A + G
Sbjct: 3584 LRISTAQVEDTGRYTCLASSPAG 3606
Score = 86.6 bits (205), Expect = 2e-16
Identities = 73/280 (26%), Positives = 117/280 (41%), Gaps = 22/280 (7%)
Query: 91 VGPQIRYTVD-VTIYENSETSVALAILGATGHTNVWETTR--------RITSEQHGNTNF 141
V P+IR T T+ ENS+ + G W+ + T+E +G
Sbjct: 4167 VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELIL 4226
Query: 142 R-MIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ +D+G Y C +++ A + HTV + V + V+ +G L C+A G
Sbjct: 4227 ENVVLEDSGFYTC-VANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATG 4285
Query: 201 NPVPTVTWHRLND----SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P+P +TW N+ + +L + R+ + G Y CT +N VG F +
Sbjct: 4286 IPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGF-VY 4344
Query: 257 VLYPPEITVE--RSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP + +W+ G A L C V DP + W + + S R+ GS
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGG-NAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGS 4403
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
L I ED G+Y+CVA N G R + ++ + P
Sbjct: 4404 ---LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 86.2 bits (204), Expect = 2e-16
Identities = 54/217 (24%), Positives = 96/217 (44%), Gaps = 10/217 (4%)
Query: 147 DAGDYVCQISDRVARDQV-HTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C + ++ + V+VLVPP++ ET + L+C G+P PT
Sbjct: 1706 DRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPT 1765
Query: 206 VTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W + D L G +L +++ + + G+Y C N G EF++ V
Sbjct: 1766 IMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH-KKEFEVTVHV 1824
Query: 260 PPEITVERSWVHTGEGFR-AELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP I ++ L C P ++W ++ P++ ++ + + S L
Sbjct: 1825 PPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKIQSSGRVL 1883
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
IA ED G Y+CVA N+ G ++H+++ P+
Sbjct: 1884 QIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPS 1920
Score = 86.2 bits (204), Expect = 2e-16
Identities = 61/219 (27%), Positives = 96/219 (43%), Gaps = 11/219 (5%)
Query: 147 DAGDYVC-QISDRVARDQVHTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNPV 203
D G+Y C I+ + ++ V VPPS++ S V R G + LEC + P
Sbjct: 3029 DGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPP 3088
Query: 204 PTVTWHR----LNDSS--SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P +TW++ + +S+ L +G L + + E G Y C N G F L V
Sbjct: 3089 PVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDD-KNFHLNV 3147
Query: 258 LYPPEIT-VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP I ER + L C PP ++W +N + S+ + +
Sbjct: 3148 YVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGS 3207
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L IA Q D GNY+C+A N G+A+++ +S + P+
Sbjct: 3208 KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPS 3246
Score = 84.6 bits (200), Expect = 7e-16
Identities = 62/214 (28%), Positives = 93/214 (43%), Gaps = 13/214 (6%)
Query: 142 RMIFQDAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
R+ +D+G YVC + V + + V V PP + + + GG A+L C G
Sbjct: 4317 RVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL-GGNAILNCEVKG 4375
Query: 201 NPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
+P PT+ W+R ++ +LG G L + G Y C N G V
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQLGNG-SLAIYGTVNEDAGDYTCVATNEAG-VVERSMS 4433
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
L + PP IT+E G + L C +P ++W + +S +RV + S
Sbjct: 4434 LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL---S 4490
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
N++L IAD Q ED + CVA N +G V V
Sbjct: 4491 NNSLYIADAQKEDTSEFECVARNLMGSVLVRVPV 4524
Score = 82.6 bits (195), Expect = 3e-15
Identities = 57/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 128 TRRITSEQHGNTN--FRMIFQDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHV 184
T RI +G+T + + D G Y C ++ D++ + V V P++R + +
Sbjct: 3292 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEK 3351
Query: 185 TARRGGAAV-LECRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVY 237
++ +ECRA G P P + W + L+ L G +++ R + VY
Sbjct: 3352 LMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVY 3411
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWY 295
C N G + LQV PP + ++ + +G + C P ++W
Sbjct: 3412 TCVASNRAGVDN-KHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWL 3470
Query: 296 QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
++ PL +T+S G LL A+ ED G Y+C+A N G +H
Sbjct: 3471 RDGQPLGLDAHLTVSTHGMVLQLLKAET--EDSGKYTCIASNEAGEVSKH 3518
Score = 82.2 bits (194), Expect = 4e-15
Identities = 61/210 (29%), Positives = 93/210 (44%), Gaps = 15/210 (7%)
Query: 146 QDAGDYVCQISDRVARDQV-HTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNP 202
+DAG Y C + D + + V VLVPP ++ S VT +A++EC ++G+P
Sbjct: 2841 EDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSP 2900
Query: 203 VPTVTWHR-----LNDSSSR-LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P +W + L D + L G LQ+ + G Y C +N G F L
Sbjct: 2901 APRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGS-AKKYFNLN 2959
Query: 257 VLYPPEITVERSWVHTG--EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP + +S T F L C V PP ++SW +N P+ + + G
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNF-ISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGG- 3017
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARR 344
TL I + D G Y+C+A N G +++
Sbjct: 3018 -RTLQIIRAKVSDGGEYTCIAINQAGESKK 3046
Score = 81.0 bits (191), Expect = 9e-15
Identities = 60/200 (30%), Positives = 85/200 (42%), Gaps = 13/200 (6%)
Query: 148 AGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
AG Y C + H T+ V PP ++ P HV +L C A G P P +
Sbjct: 3962 AGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNN--PILLPCEATGTPSPFI 4019
Query: 207 TWHR----LNDSSSRLGEGPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
TW + +N S P LQ+SR R G Y C N G + + +L V P
Sbjct: 4020 TWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGT-ALGKIKLNVQVP 4078
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I+ L C PP +++W+++ + S R + + GS L I
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGS---LQI 4135
Query: 321 ADVQPEDFGNYSCVADNSLG 340
A VQP D G+Y+C+A N G
Sbjct: 4136 AFVQPGDAGHYTCMAANVAG 4155
Score = 76.6 bits (180), Expect = 2e-13
Identities = 79/315 (25%), Positives = 125/315 (39%), Gaps = 31/315 (9%)
Query: 84 YNLQITDVGPQIR---YTVDVTIYENSETSVALAILGATGHTNVW-----ETTRRITSEQ 135
YNL++ V P I+ +V++ N T++ + G +W + T T +
Sbjct: 1351 YNLKV-HVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQT 1409
Query: 136 HGNTNFRMIF----QDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGG 190
N +F +DAG Y C+ + Q + ++VLVPP++ + V+
Sbjct: 1410 VNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNR 1469
Query: 191 AAVLECRAAGNPVPTVTWHR------LNDSS-SRLGEGPQLQLSRLERHHGGVYACTVDN 243
LEC+ G P P + W + L D + L G L L R+ G Y CTV N
Sbjct: 1470 DVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSN 1529
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRA--ELVCTVLADPPAEVSWYQNSFPL 301
G + +L + PP I + +L C P ++WY++ P+
Sbjct: 1530 AAGKQ-AKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPI 1588
Query: 302 SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTS 359
+S + +G L I Q D Y+C N G A + HV+V P +
Sbjct: 1589 MSSSQALYIDKG--QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLA 1646
Query: 360 PPLAR---APHSYTL 371
PL + HS TL
Sbjct: 1647 TPLNKQVVIAHSLTL 1661
Score = 76.6 bits (180), Expect = 2e-13
Identities = 60/225 (26%), Positives = 93/225 (41%), Gaps = 21/225 (9%)
Query: 149 GDYVCQISDRVA-RDQVHTVEVLVPPSVR---ASPETRHVTARRGGAAVLECRAAGNPVP 204
G Y C S + + ++ V V P++ + VT L C A P
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPA 2605
Query: 205 TVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
T+TW + N + L G LQ+ + + G Y+C N G ++ ++++V
Sbjct: 2606 TITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGE-MIKHYEVKVY 2664
Query: 259 YPPEITVERSW--------VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
PP I W V L C A P A +SWY++ PL + + V ++
Sbjct: 2665 IPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIA 2724
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
A G HTL I + Q D G Y+CVA N G +V+ + P+
Sbjct: 2725 ANG--HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPS 2767
Score = 75.8 bits (178), Expect = 3e-13
Identities = 64/227 (28%), Positives = 91/227 (40%), Gaps = 18/227 (7%)
Query: 146 QDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G Y C S D + + V V VPP++ + E R +T R LEC++ P P
Sbjct: 3592 EDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 205 TVTWHRLND---SSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TW R + ++ R L G LQ++ + Y C N G EF L V
Sbjct: 3652 VITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAG-KTTREFILTVN 3710
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNHT 317
PP I + L C P ++W ++ L+ + R ++ G H
Sbjct: 3711 VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH- 3769
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARR------HVEVSGRPGPARFT 358
I D G Y C+A N+ G RR HV S PGP T
Sbjct: 3770 --IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMT 3814
Score = 75.4 bits (177), Expect = 4e-13
Identities = 62/214 (28%), Positives = 94/214 (43%), Gaps = 18/214 (8%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTV-EVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ D G Y C + T +V PP V P +VT G AVL C
Sbjct: 488 KVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPN--NVTVTPGERAVLTCLIIS 545
Query: 201 NPVPTVTWHRLNDSSSRLGEGPQ--------LQLSRLERHHGGVYACTVDNGVGPPVVTE 252
+TW R ND RL E + L+L ++ + G Y C V + G +
Sbjct: 546 AVDYNLTWQR-NDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASV 604
Query: 253 FQLQVLYPPEITV-ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA 311
F L V PP++TV ++ TG G ++C+ P +++W N + S R M++
Sbjct: 605 F-LTVQEPPKVTVMPKNQSFTG-GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTS 662
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
G TL I + P+D G Y C+A NS G +++
Sbjct: 663 DG---TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693
Score = 73.7 bits (173), Expect = 1e-12
Identities = 60/211 (28%), Positives = 88/211 (41%), Gaps = 18/211 (8%)
Query: 147 DAGDYVCQISDRVARDQVHTVE--VLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D+G Y+C ++ +A + V+ V VPP ++ P +H+ + G + C A G P+P
Sbjct: 1144 DSGMYLC-VATNIAGNVTQAVKLNVHVPPKIQRGP--KHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 205 TVTWHRLNDSSSRLGE----GPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TW + + GE P L + + G+Y C N G TE L V
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTD-ETEITLHVQ 1259
Query: 259 YPPEI-TVERSWVHTGE----GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
PP + +E + T + R E C P + W N L+ E +S
Sbjct: 1260 EPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGRE-PGISILE 1318
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
L+IA V P D G Y CVA N G R
Sbjct: 1319 DGTLLVIASVTPYDNGEYICVAVNEAGTTER 1349
Score = 73.7 bits (173), Expect = 1e-12
Identities = 56/219 (25%), Positives = 89/219 (40%), Gaps = 13/219 (5%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C +S+ + + + +PPS++ T ++ LEC G P+P
Sbjct: 1519 DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPA 1578
Query: 206 VTWHRLND---SSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+TW++ SSS+ + +G L + R + Y C V N G F + V
Sbjct: 1579 ITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAG-TAEKSFHVDVYV 1637
Query: 260 PPEITVERSWVHTGEGFRAE---LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP I + + A L C +P ++W ++ P+ A++ + + A G
Sbjct: 1638 PPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKK- 1696
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L I Q D G Y CVA + G EV PA
Sbjct: 1697 -LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPA 1734
Score = 72.9 bits (171), Expect = 2e-12
Identities = 75/332 (22%), Positives = 123/332 (37%), Gaps = 28/332 (8%)
Query: 88 ITDVGPQIRYTVDVTIYENSETSVALAILGATGHTNVWETT---------RRITSEQHGN 138
+++ P I+ +VT+ + I+ A + W+ RI + + +
Sbjct: 516 VSEPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS 575
Query: 139 TNFRMI-FQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLEC 196
+ + F DAG+Y C +S + V PP V P+ + T G + C
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTG--GSEVSIMC 633
Query: 197 RAAGNPVPTVTWHRLNDS------SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVV 250
A G P P + W +ND R+ L + G+Y C N G
Sbjct: 634 SATGYPKPKIAW-TVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQ 692
Query: 251 TEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
L+ + P++ V +S + G + C PP +V W++ L S + +
Sbjct: 693 NS-TLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIID 751
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPP--LARAPHS 368
L I + Q D G+Y+CVA N GRA + + P P +
Sbjct: 752 PLLG--LLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSN 809
Query: 369 YTLSFAVDSYPPLDELRLLYRQLAINESFQQP 400
TL V YP E + +R+L F +P
Sbjct: 810 VTLPCYVQGYP---EPTIKWRRLDNMPIFSRP 838
Score = 71.7 bits (168), Expect = 5e-12
Identities = 60/213 (28%), Positives = 90/213 (42%), Gaps = 16/213 (7%)
Query: 147 DAGDYVCQISDRVARDQVHT---VEVLVPPSVRASPETRHVTARRGGAAVLECRA-AGNP 202
D G Y+C+ ++ + Q T V LV P + SP +V G L C AGNP
Sbjct: 861 DKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVI--EGQQLTLPCTLLAGNP 918
Query: 203 VPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPP-VVTEFQLQ 256
+P W + L + + L + R++ GG Y C N G T +
Sbjct: 919 IPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH 978
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
VL P I + + T EG L C +P V W + +S S SA G++
Sbjct: 979 VL--PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSS-AKFSA-GADG 1034
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+L + E+ G Y C A N+ G A+R V+++
Sbjct: 1035 SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLT 1067
Score = 71.3 bits (167), Expect = 7e-12
Identities = 75/306 (24%), Positives = 120/306 (39%), Gaps = 31/306 (10%)
Query: 100 DVTIYENSETSVALAILGATGHTNVWETTRRITSEQHGNTNFRMI-----------FQDA 148
++T+ N +T++A G + W + + ++R++ D
Sbjct: 3812 NMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 3871
Query: 149 GDYVCQISDRVARDQVHTVE--VLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
Y C +++ A D TV+ V VPPS+ P VT + AV+ C A+G P P++
Sbjct: 3872 ATYECTVTNG-AGDDKRTVDLTVQVPPSIADEPTDFLVT--KHAPAVITCTASGVPFPSI 3928
Query: 207 TWHRLNDSSSRLGEGPQL------QLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
W + G+G ++ ++ + +H G Y C N G L V P
Sbjct: 3929 HWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGS-AHRHVTLHVHEP 3987
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I + S +H L C P ++W + ++ S R A + L I
Sbjct: 3988 PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGR--NHAVLPSGGLQI 4045
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR----APHSYTLSFAVD 376
+ ED G Y CVA N G A ++++ + P SP L TLS D
Sbjct: 4046 SRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPV--ISPHLKEYVIAVDKPITLSCEAD 4103
Query: 377 SYPPLD 382
PP D
Sbjct: 4104 GLPPPD 4109
Score = 70.9 bits (166), Expect = 1e-11
Identities = 58/209 (27%), Positives = 86/209 (41%), Gaps = 14/209 (6%)
Query: 147 DAGDYVCQISDRVAR-DQVHTVEVLVPPSVRAS-PETRHVTARRGGAAVLECRAAGNPVP 204
DA Y C S+ + + ++V + P++ S + RG + LEC G P P
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 205 TVTW----HRLNDSS--SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
TVTW H L + L EG LQL + G Y C N G ++ L V
Sbjct: 2323 TVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG-MTDKKYDLSVH 2381
Query: 259 YPPEITVER---SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
PP I + E L C P ++W+++ +P+S S V + + G
Sbjct: 2382 APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGG-- 2439
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARR 344
L + ED G Y+CV N+ G R+
Sbjct: 2440 RMLRLMQTTMEDAGQYTCVVRNAAGEERK 2468
Score = 70.9 bits (166), Expect = 1e-11
Identities = 61/210 (29%), Positives = 86/210 (40%), Gaps = 16/210 (7%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C ++ D+ ++V VPPS+ P ++T L C A G P P+
Sbjct: 3777 DTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPT--NMTVIVNVQTTLACEATGIPKPS 3834
Query: 206 VTW----HRLN----DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W H LN +S RL L + Y CTV NG G T L V
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRT-VDLTV 3893
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL-SASERVTMSARGSNH 316
PP I E + + A + CT P + W +N L + + + G+
Sbjct: 3894 QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGA-- 3951
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHV 346
+ I Q G Y+CVA N+ G A RHV
Sbjct: 3952 -IEILATQLNHAGRYTCVARNAAGSAHRHV 3980
Score = 69.7 bits (163), Expect = 2e-11
Identities = 56/201 (27%), Positives = 83/201 (41%), Gaps = 14/201 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
DAG Y C ++ T + V VPP +R++ H T A+L C A G P P
Sbjct: 4142 DAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG--HYTVNENSQAILPCVADGIPTPA 4199
Query: 206 VTWHRLND-SSSRLGEGP-----QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W + N ++ LG+ +L L + G Y C +N G T L V
Sbjct: 4200 INWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHT-VSLTVHV 4258
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
P T V +G + L C P +++W N+ + A + + L+
Sbjct: 4259 LPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAH----FDSVNGHSELV 4314
Query: 320 IADVQPEDFGNYSCVADNSLG 340
I V ED G Y C A+NS+G
Sbjct: 4315 IERVSKEDSGTYVCTAENSVG 4335
Score = 69.3 bits (162), Expect = 3e-11
Identities = 54/223 (24%), Positives = 90/223 (40%), Gaps = 14/223 (6%)
Query: 147 DAGDYVC---QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D +Y C I+ + R+ + TV V PP+++ P++ + + + VLEC A G P
Sbjct: 3686 DTANYTCVASNIAGKTTREFILTVNV--PPNIKGGPQSLVILLNK--STVLECIAEGVPT 3741
Query: 204 PTVTWHR----LNDSSSRLG--EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P +TW + L + +R E L + G Y C N G LQV
Sbjct: 3742 PRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDR-RRIDLQV 3800
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + + + L C P ++W +N L+ + S+ +
Sbjct: 3801 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS 3860
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
L+I +D Y C N G +R V+++ + P+ P
Sbjct: 3861 LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEP 3903
Score = 68.9 bits (161), Expect = 4e-11
Identities = 52/213 (24%), Positives = 94/213 (44%), Gaps = 13/213 (6%)
Query: 147 DAGDYVC-QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G+Y+C +++ ++ + ++V VPP ++ + +V+ L C G P P
Sbjct: 1332 DNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPI 1391
Query: 206 VTWHRLN----DSSS--RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W++ N +SS+ + G L+L R G Y+C N G F + VL
Sbjct: 1392 IMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTS-QKYFNIDVLV 1450
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNH 316
PP I T + V L C V P ++ W+++ PL + V + RG
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG--Q 1508
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
L + + + D G Y C N+ G+ + ++++
Sbjct: 1509 VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 1541
Score = 68.1 bits (159), Expect = 7e-11
Identities = 55/211 (26%), Positives = 81/211 (38%), Gaps = 15/211 (7%)
Query: 147 DAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D+G+Y C S+ + Q + + + VPPSV + V+ G L C A G P P
Sbjct: 3218 DSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 206 VTWHR-----LNDSSSRL---GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W + + + R+ G L + G Y C N G F L V
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI-FNLNV 3336
Query: 258 LYPPEITV---ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
P I E + T + C PP +++W +N PL S + + A G
Sbjct: 3337 YVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG- 3395
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
+ I Q D Y+CVA N G +H
Sbjct: 3396 -QVIRIVRAQVSDVAVYTCVASNRAGVDNKH 3425
Score = 67.7 bits (158), Expect = 9e-11
Identities = 70/277 (25%), Positives = 110/277 (39%), Gaps = 41/277 (14%)
Query: 100 DVTIYENSETSVALAILGATGHTNVW-------ETTRRITSEQHGNTNFRMIFQD--AGD 150
DVT+ NS TS+ T W E+ R I G T + Q+ AG
Sbjct: 2584 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGR 2643
Query: 151 YVCQISDRVARDQVH-TVEVLVPPSVRASP------ETRHVTARRGGAAVLECRAAGNPV 203
Y C ++ H V+V +PP + + V + LEC A P
Sbjct: 2644 YSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPS 2703
Query: 204 PTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+++W++ +D + G LQ+ + G Y C N G + +F + +
Sbjct: 2704 ASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL-DFDVNI 2762
Query: 258 LYPPEITVERSW-----VHTGEGFRAE---------LVCTVLADPPAEVSWYQNSFPLSA 303
PP ++ W + TG A+ L C A PP ++WY++ PL++
Sbjct: 2763 QVPPSF--QKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS 2820
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
S++V + G L I + ED G Y+CVA N G
Sbjct: 2821 SDKVLILPGG--RVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 66.9 bits (156), Expect = 2e-10
Identities = 69/260 (26%), Positives = 107/260 (41%), Gaps = 27/260 (10%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHV--TARRGGAA--------VLE 195
D G Y C S+ D++ V + VPPS + E ++ T R G A L
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 196 CRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPV 249
C P PT+TW++ +D L G LQ+ R + G Y C N G
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Query: 250 VTEFQLQVLYPPEITVERS----WVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE 305
+ ++ ++VL PP I S V A + C P SW ++ PL +
Sbjct: 2859 L-QYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD 2917
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF--TSPPLA 363
+ G L I + Q D G Y CVA+N+ G A+++ ++ P+ S L
Sbjct: 2918 HHKFLSNG--RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLT 2975
Query: 364 RAPHSY-TLSFAVDSYPPLD 382
+++ +L+ V +PP D
Sbjct: 2976 VVVNNFISLTCEVSGFPPPD 2995
Score = 64.1 bits (149), Expect = 1e-09
Identities = 61/235 (25%), Positives = 99/235 (42%), Gaps = 21/235 (8%)
Query: 131 ITSEQHGNTNF-RMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRG 189
IT G+ + R+ QD G+Y C ++ VA T V+V + ++ G
Sbjct: 937 ITVRSDGSLHIERVQLQDGGEYTC-VASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEG 995
Query: 190 GAAVLECRAAGNPVPTVTWHR----LNDSSSRLGEGPQLQLSRLER--HHGGVYACTVDN 243
L C+A+GNP P+V W + ++ SS++ G L + G Y CT N
Sbjct: 996 IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGE--------GFRAELVCTVLADPPAEVSWY 295
G + QL V P + ++ + + G L C V + PP ++W
Sbjct: 1056 TAGY-AKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 1114
Query: 296 QNSFPLSA-SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+ + +S S R T GS + I + + D G Y CVA N G + V+++
Sbjct: 1115 KETQLISPFSPRHTFLPSGS---MKITETRTSDSGMYLCVATNIAGNVTQAVKLN 1166
Score = 60.1 bits (139), Expect = 2e-08
Identities = 60/248 (24%), Positives = 95/248 (38%), Gaps = 17/248 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C + Q + V VPP++ E ++V+ A L C++ P PT
Sbjct: 2077 DTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMG--EEQNVSVLISQAVELLCQSDAIPPPT 2134
Query: 206 VTWHR-----LNDSSSRLGEGPQ-LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+TW + L + E L++ + G Y C N G + + +
Sbjct: 2135 LTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK-TEKNYNVNIWV 2193
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + E + + EG L+C PP + W + P+ +
Sbjct: 2194 PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQ 2253
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTSPP---LARAPHSYTLS 372
L I+ + D YSCVA N G A++ +++V RP S P + S +L
Sbjct: 2254 LQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLE 2313
Query: 373 FAVDSYPP 380
V PP
Sbjct: 2314 CEVQGIPP 2321
Score = 58.0 bits (134), Expect = 7e-08
Identities = 61/229 (26%), Positives = 92/229 (40%), Gaps = 14/229 (6%)
Query: 146 QDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C S+ D Q T+ + P + V G V+EC+ +G P P
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVAL--GDITVMECKTSGIPPP 731
Query: 205 TVTWHRLN---DSSSRLGEGPQLQLSRLERHH---GGVYACTVDNGVGPPVVTEFQLQVL 258
V W + + S+ L P L L +++ G Y C N G + L V
Sbjct: 732 QVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGR-ATGKITLDVG 790
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ-NSFPL-SASERVTMSARGSNH 316
PP E + V G L C V P + W + ++ P+ S V+ ++
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRH--VEVSGRPGPARFTSPPLA 363
L I ++ D G Y C A+N G+ + V V+G P SP +A
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVA 899
Score = 48.8 bits (111), Expect = 4e-05
Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 126 ETTRRITSEQHGNTN-FRMIFQDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRH 183
E + RI +G+ + + +DAGDY C ++ ++ ++ + PP + P
Sbjct: 4391 EISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETV 4450
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLNDSSS 216
+ A GG +L C+A G P PT+TW R S S
Sbjct: 4451 INA--GGKIILNCQATGEPQPTITWSRQGHSIS 4481
>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-153O3 on chromosome 1. ).
Length = 5635
Score = 98.3 bits (234), Expect = 5e-20
Identities = 61/215 (28%), Positives = 97/215 (45%), Gaps = 15/215 (6%)
Query: 146 QDAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C + + ++ + + VLVPP + V + + L C GNPVP
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509
Query: 205 TVTWHR----LNDSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TWH+ L + + + G LQ++ ++ H G Y C + G F L V
Sbjct: 2510 EITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHK-SRSFSLNVF 2568
Query: 259 YPPEITVERSWVHTGE-----GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
P I S + + LVC + PPA ++W+++ PL ++ + + G
Sbjct: 2569 VSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGG 2628
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
TL I + Q ++ G YSCVA N G +H EV
Sbjct: 2629 --RTLQILNAQEDNAGRYSCVATNEAGEMIKHYEV 2661
Score = 96.3 bits (229), Expect = 2e-19
Identities = 66/222 (29%), Positives = 100/222 (45%), Gaps = 15/222 (6%)
Query: 146 QDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
QD G Y C+ ++ + ++ + V + VPP++ S E +T G L C ++G P P
Sbjct: 2167 QDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPP 2226
Query: 205 TVTWHR-----LNDSSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
+ W + L DS R L G QLQ+S E+ +Y+C N G E+ LQ
Sbjct: 2227 NLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT-AKKEYNLQ 2285
Query: 257 VLYPPEITVERSW---VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
V P IT S + G L C V PP V+W ++ PL ++ V + G
Sbjct: 2286 VYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEG 2345
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
H L + ++ D G Y CVA N G + ++S P+
Sbjct: 2346 --HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPS 2385
Score = 91.9 bits (218), Expect = 5e-18
Identities = 57/214 (26%), Positives = 95/214 (44%), Gaps = 9/214 (4%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
+ + +DAG Y C ++ Q H + V PPS+ + + + T LEC+AAG
Sbjct: 1887 KTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAG 1946
Query: 201 NPVPTVTWHR----LNDSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
NPVP +TW++ L+ S+S L G + + + G+Y C N G + +
Sbjct: 1947 NPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELF-YS 2005
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
LQV P I+ + V L C P ++W ++ P+S+ +
Sbjct: 2006 LQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSG 2064
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
L + Q D G Y+CVA N+ G +R +++
Sbjct: 2065 GRILALTSAQISDTGRYTCVAVNAAGEKQRDIDL 2098
Score = 87.8 bits (208), Expect = 8e-17
Identities = 67/211 (31%), Positives = 92/211 (43%), Gaps = 17/211 (8%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G YVC+ + RD + + V VPPS+ PE + L C A G P PT
Sbjct: 3124 DTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG-PEREVIVETISNPVTLTCDATGIPPPT 3182
Query: 206 VTW----HRLNDSSSR----LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W R+ +S S L G +LQ++R + G Y C N G F L +
Sbjct: 3183 IAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYF-LSI 3241
Query: 258 LYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA--SERVTMSARG 313
PP + S V G ELVC P + W ++ P+++ +ER+ +SA G
Sbjct: 3242 QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG 3301
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
S TL I D G Y+CVA N G R
Sbjct: 3302 S--TLNIYGALTSDTGKYTCVATNPAGEEDR 3330
Score = 87.4 bits (207), Expect = 1e-16
Identities = 59/203 (29%), Positives = 88/203 (43%), Gaps = 12/203 (5%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D Y C S+R D H ++V PP++ S T +T +G + + C G P P+
Sbjct: 3407 DVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPS 3466
Query: 206 VTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W R L+ + G LQL + E G Y C N G V F L+VL
Sbjct: 3467 MAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG-EVSKHFILKVLE 3525
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + E + EL C P +++W ++ PL +++V G
Sbjct: 3526 PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQV--QTLGGGEV 3583
Query: 318 LLIADVQPEDFGNYSCVADNSLG 340
L I+ Q ED G Y+C+A + G
Sbjct: 3584 LRISTAQVEDTGRYTCLASSPAG 3606
Score = 86.6 bits (205), Expect = 2e-16
Identities = 73/280 (26%), Positives = 117/280 (41%), Gaps = 22/280 (7%)
Query: 91 VGPQIRYTVD-VTIYENSETSVALAILGATGHTNVWETTR--------RITSEQHGNTNF 141
V P+IR T T+ ENS+ + G W+ + T+E +G
Sbjct: 4167 VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELIL 4226
Query: 142 R-MIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ +D+G Y C +++ A + HTV + V + V+ +G L C+A G
Sbjct: 4227 ENVVLEDSGFYTC-VANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATG 4285
Query: 201 NPVPTVTWHRLND----SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P+P +TW N+ + +L + R+ + G Y CT +N VG F +
Sbjct: 4286 IPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGF-VY 4344
Query: 257 VLYPPEITVE--RSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP + +W+ G A L C V DP + W + + S R+ GS
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGG-NAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGS 4403
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
L I ED G+Y+CVA N G R + ++ + P
Sbjct: 4404 ---LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 86.2 bits (204), Expect = 2e-16
Identities = 54/217 (24%), Positives = 96/217 (44%), Gaps = 10/217 (4%)
Query: 147 DAGDYVCQISDRVARDQV-HTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C + ++ + V+VLVPP++ ET + L+C G+P PT
Sbjct: 1706 DRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPT 1765
Query: 206 VTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W + D L G +L +++ + + G+Y C N G EF++ V
Sbjct: 1766 IMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH-KKEFEVTVHV 1824
Query: 260 PPEITVERSWVHTGEGFR-AELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP I ++ L C P ++W ++ P++ ++ + + S L
Sbjct: 1825 PPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKIQSSGRVL 1883
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
IA ED G Y+CVA N+ G ++H+++ P+
Sbjct: 1884 QIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPS 1920
Score = 86.2 bits (204), Expect = 2e-16
Identities = 61/219 (27%), Positives = 96/219 (43%), Gaps = 11/219 (5%)
Query: 147 DAGDYVC-QISDRVARDQVHTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNPV 203
D G+Y C I+ + ++ V VPPS++ S V R G + LEC + P
Sbjct: 3029 DGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPP 3088
Query: 204 PTVTWHR----LNDSS--SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P +TW++ + +S+ L +G L + + E G Y C N G F L V
Sbjct: 3089 PVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDD-KNFHLNV 3147
Query: 258 LYPPEIT-VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP I ER + L C PP ++W +N + S+ + +
Sbjct: 3148 YVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGS 3207
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L IA Q D GNY+C+A N G+A+++ +S + P+
Sbjct: 3208 KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPS 3246
Score = 84.6 bits (200), Expect = 7e-16
Identities = 62/214 (28%), Positives = 93/214 (43%), Gaps = 13/214 (6%)
Query: 142 RMIFQDAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
R+ +D+G YVC + V + + V V PP + + + GG A+L C G
Sbjct: 4317 RVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL-GGNAILNCEVKG 4375
Query: 201 NPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
+P PT+ W+R ++ +LG G L + G Y C N G V
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQLGNG-SLAIYGTVNEDAGDYTCVATNEAG-VVERSMS 4433
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
L + PP IT+E G + L C +P ++W + +S +RV + S
Sbjct: 4434 LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL---S 4490
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
N++L IAD Q ED + CVA N +G V V
Sbjct: 4491 NNSLYIADAQKEDTSEFECVARNLMGSVLVRVPV 4524
Score = 82.6 bits (195), Expect = 3e-15
Identities = 57/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 128 TRRITSEQHGNTN--FRMIFQDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHV 184
T RI +G+T + + D G Y C ++ D++ + V V P++R + +
Sbjct: 3292 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEK 3351
Query: 185 TARRGGAAV-LECRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVY 237
++ +ECRA G P P + W + L+ L G +++ R + VY
Sbjct: 3352 LMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVY 3411
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWY 295
C N G + LQV PP + ++ + +G + C P ++W
Sbjct: 3412 TCVASNRAGVDN-KHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWL 3470
Query: 296 QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
++ PL +T+S G LL A+ ED G Y+C+A N G +H
Sbjct: 3471 RDGQPLGLDAHLTVSTHGMVLQLLKAET--EDSGKYTCIASNEAGEVSKH 3518
Score = 82.2 bits (194), Expect = 4e-15
Identities = 61/210 (29%), Positives = 93/210 (44%), Gaps = 15/210 (7%)
Query: 146 QDAGDYVCQISDRVARDQV-HTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNP 202
+DAG Y C + D + + V VLVPP ++ S VT +A++EC ++G+P
Sbjct: 2841 EDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSP 2900
Query: 203 VPTVTWHR-----LNDSSSR-LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P +W + L D + L G LQ+ + G Y C +N G F L
Sbjct: 2901 APRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGS-AKKYFNLN 2959
Query: 257 VLYPPEITVERSWVHTG--EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP + +S T F L C V PP ++SW +N P+ + + G
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNF-ISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGG- 3017
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARR 344
TL I + D G Y+C+A N G +++
Sbjct: 3018 -RTLQIIRAKVSDGGEYTCIAINQAGESKK 3046
Score = 81.0 bits (191), Expect = 9e-15
Identities = 60/200 (30%), Positives = 85/200 (42%), Gaps = 13/200 (6%)
Query: 148 AGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
AG Y C + H T+ V PP ++ P HV +L C A G P P +
Sbjct: 3962 AGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNN--PILLPCEATGTPSPFI 4019
Query: 207 TWHR----LNDSSSRLGEGPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
TW + +N S P LQ+SR R G Y C N G + + +L V P
Sbjct: 4020 TWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGT-ALGKIKLNVQVP 4078
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I+ L C PP +++W+++ + S R + + GS L I
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGS---LQI 4135
Query: 321 ADVQPEDFGNYSCVADNSLG 340
A VQP D G+Y+C+A N G
Sbjct: 4136 AFVQPGDAGHYTCMAANVAG 4155
Score = 76.6 bits (180), Expect = 2e-13
Identities = 79/315 (25%), Positives = 125/315 (39%), Gaps = 31/315 (9%)
Query: 84 YNLQITDVGPQIR---YTVDVTIYENSETSVALAILGATGHTNVW-----ETTRRITSEQ 135
YNL++ V P I+ +V++ N T++ + G +W + T T +
Sbjct: 1351 YNLKV-HVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQT 1409
Query: 136 HGNTNFRMIF----QDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGG 190
N +F +DAG Y C+ + Q + ++VLVPP++ + V+
Sbjct: 1410 VNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNR 1469
Query: 191 AAVLECRAAGNPVPTVTWHR------LNDSS-SRLGEGPQLQLSRLERHHGGVYACTVDN 243
LEC+ G P P + W + L D + L G L L R+ G Y CTV N
Sbjct: 1470 DVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSN 1529
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRA--ELVCTVLADPPAEVSWYQNSFPL 301
G + +L + PP I + +L C P ++WY++ P+
Sbjct: 1530 AAGKQ-AKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPI 1588
Query: 302 SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTS 359
+S + +G L I Q D Y+C N G A + HV+V P +
Sbjct: 1589 MSSSQALYIDKG--QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLA 1646
Query: 360 PPLAR---APHSYTL 371
PL + HS TL
Sbjct: 1647 TPLNKQVVIAHSLTL 1661
Score = 76.6 bits (180), Expect = 2e-13
Identities = 60/225 (26%), Positives = 93/225 (41%), Gaps = 21/225 (9%)
Query: 149 GDYVCQISDRVA-RDQVHTVEVLVPPSVR---ASPETRHVTARRGGAAVLECRAAGNPVP 204
G Y C S + + ++ V V P++ + VT L C A P
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPA 2605
Query: 205 TVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
T+TW + N + L G LQ+ + + G Y+C N G ++ ++++V
Sbjct: 2606 TITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGE-MIKHYEVKVY 2664
Query: 259 YPPEITVERSW--------VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
PP I W V L C A P A +SWY++ PL + + V ++
Sbjct: 2665 IPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIA 2724
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
A G HTL I + Q D G Y+CVA N G +V+ + P+
Sbjct: 2725 ANG--HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPS 2767
Score = 75.8 bits (178), Expect = 3e-13
Identities = 64/227 (28%), Positives = 91/227 (40%), Gaps = 18/227 (7%)
Query: 146 QDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G Y C S D + + V V VPP++ + E R +T R LEC++ P P
Sbjct: 3592 EDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 205 TVTWHRLND---SSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TW R + ++ R L G LQ++ + Y C N G EF L V
Sbjct: 3652 VITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAG-KTTREFILTVN 3710
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNHT 317
PP I + L C P ++W ++ L+ + R ++ G H
Sbjct: 3711 VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH- 3769
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARR------HVEVSGRPGPARFT 358
I D G Y C+A N+ G RR HV S PGP T
Sbjct: 3770 --IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMT 3814
Score = 75.4 bits (177), Expect = 4e-13
Identities = 62/214 (28%), Positives = 94/214 (43%), Gaps = 18/214 (8%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTV-EVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ D G Y C + T +V PP V P +VT G AVL C
Sbjct: 488 KVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPN--NVTVTPGERAVLTCLIIS 545
Query: 201 NPVPTVTWHRLNDSSSRLGEGPQ--------LQLSRLERHHGGVYACTVDNGVGPPVVTE 252
+TW R ND RL E + L+L ++ + G Y C V + G +
Sbjct: 546 AVDYNLTWQR-NDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASV 604
Query: 253 FQLQVLYPPEITV-ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA 311
F L V PP++TV ++ TG G ++C+ P +++W N + S R M++
Sbjct: 605 F-LTVQEPPKVTVMPKNQSFTG-GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTS 662
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
G TL I + P+D G Y C+A NS G +++
Sbjct: 663 DG---TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693
Score = 73.7 bits (173), Expect = 1e-12
Identities = 60/211 (28%), Positives = 88/211 (41%), Gaps = 18/211 (8%)
Query: 147 DAGDYVCQISDRVARDQVHTVE--VLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D+G Y+C ++ +A + V+ V VPP ++ P +H+ + G + C A G P+P
Sbjct: 1144 DSGMYLC-VATNIAGNVTQAVKLNVHVPPKIQRGP--KHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 205 TVTWHRLNDSSSRLGE----GPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TW + + GE P L + + G+Y C N G TE L V
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTD-ETEITLHVQ 1259
Query: 259 YPPEI-TVERSWVHTGE----GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
PP + +E + T + R E C P + W N L+ E +S
Sbjct: 1260 EPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGRE-PGISILE 1318
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
L+IA V P D G Y CVA N G R
Sbjct: 1319 DGTLLVIASVTPYDNGEYICVAVNEAGTTER 1349
Score = 73.7 bits (173), Expect = 1e-12
Identities = 56/219 (25%), Positives = 89/219 (40%), Gaps = 13/219 (5%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C +S+ + + + +PPS++ T ++ LEC G P+P
Sbjct: 1519 DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPA 1578
Query: 206 VTWHRLND---SSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+TW++ SSS+ + +G L + R + Y C V N G F + V
Sbjct: 1579 ITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAG-TAEKSFHVDVYV 1637
Query: 260 PPEITVERSWVHTGEGFRAE---LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP I + + A L C +P ++W ++ P+ A++ + + A G
Sbjct: 1638 PPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKK- 1696
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L I Q D G Y CVA + G EV PA
Sbjct: 1697 -LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPA 1734
Score = 72.9 bits (171), Expect = 2e-12
Identities = 75/332 (22%), Positives = 123/332 (37%), Gaps = 28/332 (8%)
Query: 88 ITDVGPQIRYTVDVTIYENSETSVALAILGATGHTNVWETT---------RRITSEQHGN 138
+++ P I+ +VT+ + I+ A + W+ RI + + +
Sbjct: 516 VSEPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS 575
Query: 139 TNFRMI-FQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLEC 196
+ + F DAG+Y C +S + V PP V P+ + T G + C
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTG--GSEVSIMC 633
Query: 197 RAAGNPVPTVTWHRLNDS------SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVV 250
A G P P + W +ND R+ L + G+Y C N G
Sbjct: 634 SATGYPKPKIAW-TVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQ 692
Query: 251 TEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
L+ + P++ V +S + G + C PP +V W++ L S + +
Sbjct: 693 NS-TLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIID 751
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPP--LARAPHS 368
L I + Q D G+Y+CVA N GRA + + P P +
Sbjct: 752 PLLG--LLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSN 809
Query: 369 YTLSFAVDSYPPLDELRLLYRQLAINESFQQP 400
TL V YP E + +R+L F +P
Sbjct: 810 VTLPCYVQGYP---EPTIKWRRLDNMPIFSRP 838
Score = 71.7 bits (168), Expect = 5e-12
Identities = 60/213 (28%), Positives = 90/213 (42%), Gaps = 16/213 (7%)
Query: 147 DAGDYVCQISDRVARDQVHT---VEVLVPPSVRASPETRHVTARRGGAAVLECRA-AGNP 202
D G Y+C+ ++ + Q T V LV P + SP +V G L C AGNP
Sbjct: 861 DKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVI--EGQQLTLPCTLLAGNP 918
Query: 203 VPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPP-VVTEFQLQ 256
+P W + L + + L + R++ GG Y C N G T +
Sbjct: 919 IPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH 978
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
VL P I + + T EG L C +P V W + +S S SA G++
Sbjct: 979 VL--PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSS-AKFSA-GADG 1034
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+L + E+ G Y C A N+ G A+R V+++
Sbjct: 1035 SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLT 1067
Score = 71.3 bits (167), Expect = 7e-12
Identities = 75/306 (24%), Positives = 120/306 (39%), Gaps = 31/306 (10%)
Query: 100 DVTIYENSETSVALAILGATGHTNVWETTRRITSEQHGNTNFRMI-----------FQDA 148
++T+ N +T++A G + W + + ++R++ D
Sbjct: 3812 NMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 3871
Query: 149 GDYVCQISDRVARDQVHTVE--VLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
Y C +++ A D TV+ V VPPS+ P VT + AV+ C A+G P P++
Sbjct: 3872 ATYECTVTNG-AGDDKRTVDLTVQVPPSIADEPTDFLVT--KHAPAVITCTASGVPFPSI 3928
Query: 207 TWHRLNDSSSRLGEGPQL------QLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
W + G+G ++ ++ + +H G Y C N G L V P
Sbjct: 3929 HWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGS-AHRHVTLHVHEP 3987
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I + S +H L C P ++W + ++ S R A + L I
Sbjct: 3988 PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGR--NHAVLPSGGLQI 4045
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR----APHSYTLSFAVD 376
+ ED G Y CVA N G A ++++ + P SP L TLS D
Sbjct: 4046 SRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPV--ISPHLKEYVIAVDKPITLSCEAD 4103
Query: 377 SYPPLD 382
PP D
Sbjct: 4104 GLPPPD 4109
Score = 70.9 bits (166), Expect = 1e-11
Identities = 58/209 (27%), Positives = 86/209 (41%), Gaps = 14/209 (6%)
Query: 147 DAGDYVCQISDRVAR-DQVHTVEVLVPPSVRAS-PETRHVTARRGGAAVLECRAAGNPVP 204
DA Y C S+ + + ++V + P++ S + RG + LEC G P P
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 205 TVTW----HRLNDSS--SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
TVTW H L + L EG LQL + G Y C N G ++ L V
Sbjct: 2323 TVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG-MTDKKYDLSVH 2381
Query: 259 YPPEITVER---SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
PP I + E L C P ++W+++ +P+S S V + + G
Sbjct: 2382 APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGG-- 2439
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARR 344
L + ED G Y+CV N+ G R+
Sbjct: 2440 RMLRLMQTTMEDAGQYTCVVRNAAGEERK 2468
Score = 70.9 bits (166), Expect = 1e-11
Identities = 61/210 (29%), Positives = 86/210 (40%), Gaps = 16/210 (7%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C ++ D+ ++V VPPS+ P ++T L C A G P P+
Sbjct: 3777 DTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPT--NMTVIVNVQTTLACEATGIPKPS 3834
Query: 206 VTW----HRLN----DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W H LN +S RL L + Y CTV NG G T L V
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRT-VDLTV 3893
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL-SASERVTMSARGSNH 316
PP I E + + A + CT P + W +N L + + + G+
Sbjct: 3894 QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGA-- 3951
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHV 346
+ I Q G Y+CVA N+ G A RHV
Sbjct: 3952 -IEILATQLNHAGRYTCVARNAAGSAHRHV 3980
Score = 69.7 bits (163), Expect = 2e-11
Identities = 56/201 (27%), Positives = 83/201 (41%), Gaps = 14/201 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
DAG Y C ++ T + V VPP +R++ H T A+L C A G P P
Sbjct: 4142 DAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG--HYTVNENSQAILPCVADGIPTPA 4199
Query: 206 VTWHRLND-SSSRLGEGP-----QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W + N ++ LG+ +L L + G Y C +N G T L V
Sbjct: 4200 INWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHT-VSLTVHV 4258
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
P T V +G + L C P +++W N+ + A + + L+
Sbjct: 4259 LPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAH----FDSVNGHSELV 4314
Query: 320 IADVQPEDFGNYSCVADNSLG 340
I V ED G Y C A+NS+G
Sbjct: 4315 IERVSKEDSGTYVCTAENSVG 4335
Score = 69.3 bits (162), Expect = 3e-11
Identities = 54/223 (24%), Positives = 90/223 (40%), Gaps = 14/223 (6%)
Query: 147 DAGDYVC---QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D +Y C I+ + R+ + TV V PP+++ P++ + + + VLEC A G P
Sbjct: 3686 DTANYTCVASNIAGKTTREFILTVNV--PPNIKGGPQSLVILLNK--STVLECIAEGVPT 3741
Query: 204 PTVTWHR----LNDSSSRLG--EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P +TW + L + +R E L + G Y C N G LQV
Sbjct: 3742 PRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDR-RRIDLQV 3800
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + + + L C P ++W +N L+ + S+ +
Sbjct: 3801 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS 3860
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
L+I +D Y C N G +R V+++ + P+ P
Sbjct: 3861 LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEP 3903
Score = 68.9 bits (161), Expect = 4e-11
Identities = 52/213 (24%), Positives = 94/213 (44%), Gaps = 13/213 (6%)
Query: 147 DAGDYVC-QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G+Y+C +++ ++ + ++V VPP ++ + +V+ L C G P P
Sbjct: 1332 DNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPI 1391
Query: 206 VTWHRLN----DSSS--RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W++ N +SS+ + G L+L R G Y+C N G F + VL
Sbjct: 1392 IMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTS-QKYFNIDVLV 1450
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNH 316
PP I T + V L C V P ++ W+++ PL + V + RG
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG--Q 1508
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
L + + + D G Y C N+ G+ + ++++
Sbjct: 1509 VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 1541
Score = 68.1 bits (159), Expect = 7e-11
Identities = 55/211 (26%), Positives = 81/211 (38%), Gaps = 15/211 (7%)
Query: 147 DAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D+G+Y C S+ + Q + + + VPPSV + V+ G L C A G P P
Sbjct: 3218 DSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 206 VTWHR-----LNDSSSRL---GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W + + + R+ G L + G Y C N G F L V
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI-FNLNV 3336
Query: 258 LYPPEITV---ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
P I E + T + C PP +++W +N PL S + + A G
Sbjct: 3337 YVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG- 3395
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
+ I Q D Y+CVA N G +H
Sbjct: 3396 -QVIRIVRAQVSDVAVYTCVASNRAGVDNKH 3425
Score = 67.7 bits (158), Expect = 9e-11
Identities = 70/277 (25%), Positives = 110/277 (39%), Gaps = 41/277 (14%)
Query: 100 DVTIYENSETSVALAILGATGHTNVW-------ETTRRITSEQHGNTNFRMIFQD--AGD 150
DVT+ NS TS+ T W E+ R I G T + Q+ AG
Sbjct: 2584 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGR 2643
Query: 151 YVCQISDRVARDQVH-TVEVLVPPSVRASP------ETRHVTARRGGAAVLECRAAGNPV 203
Y C ++ H V+V +PP + + V + LEC A P
Sbjct: 2644 YSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPS 2703
Query: 204 PTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+++W++ +D + G LQ+ + G Y C N G + +F + +
Sbjct: 2704 ASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL-DFDVNI 2762
Query: 258 LYPPEITVERSW-----VHTGEGFRAE---------LVCTVLADPPAEVSWYQNSFPLSA 303
PP ++ W + TG A+ L C A PP ++WY++ PL++
Sbjct: 2763 QVPPSF--QKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS 2820
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
S++V + G L I + ED G Y+CVA N G
Sbjct: 2821 SDKVLILPGG--RVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 66.9 bits (156), Expect = 2e-10
Identities = 69/260 (26%), Positives = 107/260 (41%), Gaps = 27/260 (10%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHV--TARRGGAA--------VLE 195
D G Y C S+ D++ V + VPPS + E ++ T R G A L
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 196 CRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPV 249
C P PT+TW++ +D L G LQ+ R + G Y C N G
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Query: 250 VTEFQLQVLYPPEITVERS----WVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE 305
+ ++ ++VL PP I S V A + C P SW ++ PL +
Sbjct: 2859 L-QYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD 2917
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF--TSPPLA 363
+ G L I + Q D G Y CVA+N+ G A+++ ++ P+ S L
Sbjct: 2918 HHKFLSNG--RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLT 2975
Query: 364 RAPHSY-TLSFAVDSYPPLD 382
+++ +L+ V +PP D
Sbjct: 2976 VVVNNFISLTCEVSGFPPPD 2995
Score = 64.1 bits (149), Expect = 1e-09
Identities = 61/235 (25%), Positives = 99/235 (42%), Gaps = 21/235 (8%)
Query: 131 ITSEQHGNTNF-RMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRG 189
IT G+ + R+ QD G+Y C ++ VA T V+V + ++ G
Sbjct: 937 ITVRSDGSLHIERVQLQDGGEYTC-VASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEG 995
Query: 190 GAAVLECRAAGNPVPTVTWHR----LNDSSSRLGEGPQLQLSRLER--HHGGVYACTVDN 243
L C+A+GNP P+V W + ++ SS++ G L + G Y CT N
Sbjct: 996 IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGE--------GFRAELVCTVLADPPAEVSWY 295
G + QL V P + ++ + + G L C V + PP ++W
Sbjct: 1056 TAGY-AKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 1114
Query: 296 QNSFPLSA-SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+ + +S S R T GS + I + + D G Y CVA N G + V+++
Sbjct: 1115 KETQLISPFSPRHTFLPSGS---MKITETRTSDSGMYLCVATNIAGNVTQAVKLN 1166
Score = 60.1 bits (139), Expect = 2e-08
Identities = 60/248 (24%), Positives = 95/248 (38%), Gaps = 17/248 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C + Q + V VPP++ E ++V+ A L C++ P PT
Sbjct: 2077 DTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMG--EEQNVSVLISQAVELLCQSDAIPPPT 2134
Query: 206 VTWHR-----LNDSSSRLGEGPQ-LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+TW + L + E L++ + G Y C N G + + +
Sbjct: 2135 LTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK-TEKNYNVNIWV 2193
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + E + + EG L+C PP + W + P+ +
Sbjct: 2194 PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQ 2253
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTSPP---LARAPHSYTLS 372
L I+ + D YSCVA N G A++ +++V RP S P + S +L
Sbjct: 2254 LQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLE 2313
Query: 373 FAVDSYPP 380
V PP
Sbjct: 2314 CEVQGIPP 2321
Score = 58.0 bits (134), Expect = 7e-08
Identities = 61/229 (26%), Positives = 92/229 (40%), Gaps = 14/229 (6%)
Query: 146 QDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C S+ D Q T+ + P + V G V+EC+ +G P P
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVAL--GDITVMECKTSGIPPP 731
Query: 205 TVTWHRLN---DSSSRLGEGPQLQLSRLERHH---GGVYACTVDNGVGPPVVTEFQLQVL 258
V W + + S+ L P L L +++ G Y C N G + L V
Sbjct: 732 QVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGR-ATGKITLDVG 790
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ-NSFPL-SASERVTMSARGSNH 316
PP E + V G L C V P + W + ++ P+ S V+ ++
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRH--VEVSGRPGPARFTSPPLA 363
L I ++ D G Y C A+N G+ + V V+G P SP +A
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVA 899
Score = 48.8 bits (111), Expect = 4e-05
Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 126 ETTRRITSEQHGNTN-FRMIFQDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRH 183
E + RI +G+ + + +DAGDY C ++ ++ ++ + PP + P
Sbjct: 4391 EISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETV 4450
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLNDSSS 216
+ A GG +L C+A G P PT+TW R S S
Sbjct: 4451 INA--GGKIILNCQATGEPQPTITWSRQGHSIS 4481
>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
Length = 5635
Score = 98.3 bits (234), Expect = 5e-20
Identities = 61/215 (28%), Positives = 97/215 (45%), Gaps = 15/215 (6%)
Query: 146 QDAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C + + ++ + + VLVPP + V + + L C GNPVP
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509
Query: 205 TVTWHR----LNDSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TWH+ L + + + G LQ++ ++ H G Y C + G F L V
Sbjct: 2510 EITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHK-SRSFSLNVF 2568
Query: 259 YPPEITVERSWVHTGE-----GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
P I S + + LVC + PPA ++W+++ PL ++ + + G
Sbjct: 2569 VSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGG 2628
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
TL I + Q ++ G YSCVA N G +H EV
Sbjct: 2629 --RTLQILNAQEDNAGRYSCVATNEAGEMIKHYEV 2661
Score = 96.3 bits (229), Expect = 2e-19
Identities = 66/222 (29%), Positives = 100/222 (45%), Gaps = 15/222 (6%)
Query: 146 QDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
QD G Y C+ ++ + ++ + V + VPP++ S E +T G L C ++G P P
Sbjct: 2167 QDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPP 2226
Query: 205 TVTWHR-----LNDSSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
+ W + L DS R L G QLQ+S E+ +Y+C N G E+ LQ
Sbjct: 2227 NLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT-AKKEYNLQ 2285
Query: 257 VLYPPEITVERSW---VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
V P IT S + G L C V PP V+W ++ PL ++ V + G
Sbjct: 2286 VYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEG 2345
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
H L + ++ D G Y CVA N G + ++S P+
Sbjct: 2346 --HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPS 2385
Score = 91.9 bits (218), Expect = 5e-18
Identities = 57/214 (26%), Positives = 95/214 (44%), Gaps = 9/214 (4%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
+ + +DAG Y C ++ Q H + V PPS+ + + + T LEC+AAG
Sbjct: 1887 KTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAG 1946
Query: 201 NPVPTVTWHR----LNDSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
NPVP +TW++ L+ S+S L G + + + G+Y C N G + +
Sbjct: 1947 NPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELF-YS 2005
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
LQV P I+ + V L C P ++W ++ P+S+ +
Sbjct: 2006 LQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSG 2064
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
L + Q D G Y+CVA N+ G +R +++
Sbjct: 2065 GRILALTSAQISDTGRYTCVAVNAAGEKQRDIDL 2098
Score = 87.8 bits (208), Expect = 8e-17
Identities = 67/211 (31%), Positives = 92/211 (43%), Gaps = 17/211 (8%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G YVC+ + RD + + V VPPS+ PE + L C A G P PT
Sbjct: 3124 DTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG-PEREVIVETISNPVTLTCDATGIPPPT 3182
Query: 206 VTW----HRLNDSSSR----LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W R+ +S S L G +LQ++R + G Y C N G F L +
Sbjct: 3183 IAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYF-LSI 3241
Query: 258 LYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA--SERVTMSARG 313
PP + S V G ELVC P + W ++ P+++ +ER+ +SA G
Sbjct: 3242 QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG 3301
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
S TL I D G Y+CVA N G R
Sbjct: 3302 S--TLNIYGALTSDTGKYTCVATNPAGEEDR 3330
Score = 87.4 bits (207), Expect = 1e-16
Identities = 59/203 (29%), Positives = 88/203 (43%), Gaps = 12/203 (5%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D Y C S+R D H ++V PP++ S T +T +G + + C G P P+
Sbjct: 3407 DVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPS 3466
Query: 206 VTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W R L+ + G LQL + E G Y C N G V F L+VL
Sbjct: 3467 MAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG-EVSKHFILKVLE 3525
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + E + EL C P +++W ++ PL +++V G
Sbjct: 3526 PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQV--QTLGGGEV 3583
Query: 318 LLIADVQPEDFGNYSCVADNSLG 340
L I+ Q ED G Y+C+A + G
Sbjct: 3584 LRISTAQVEDTGRYTCLASSPAG 3606
Score = 86.6 bits (205), Expect = 2e-16
Identities = 73/280 (26%), Positives = 117/280 (41%), Gaps = 22/280 (7%)
Query: 91 VGPQIRYTVD-VTIYENSETSVALAILGATGHTNVWETTR--------RITSEQHGNTNF 141
V P+IR T T+ ENS+ + G W+ + T+E +G
Sbjct: 4167 VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELIL 4226
Query: 142 R-MIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ +D+G Y C +++ A + HTV + V + V+ +G L C+A G
Sbjct: 4227 ENVVLEDSGFYTC-VANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATG 4285
Query: 201 NPVPTVTWHRLND----SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P+P +TW N+ + +L + R+ + G Y CT +N VG F +
Sbjct: 4286 IPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGF-VY 4344
Query: 257 VLYPPEITVE--RSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP + +W+ G A L C V DP + W + + S R+ GS
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGG-NAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGS 4403
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
L I ED G+Y+CVA N G R + ++ + P
Sbjct: 4404 ---LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 86.2 bits (204), Expect = 2e-16
Identities = 54/217 (24%), Positives = 96/217 (44%), Gaps = 10/217 (4%)
Query: 147 DAGDYVCQISDRVARDQV-HTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C + ++ + V+VLVPP++ ET + L+C G+P PT
Sbjct: 1706 DRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPT 1765
Query: 206 VTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W + D L G +L +++ + + G+Y C N G EF++ V
Sbjct: 1766 IMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH-KKEFEVTVHV 1824
Query: 260 PPEITVERSWVHTGEGFR-AELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP I ++ L C P ++W ++ P++ ++ + + S L
Sbjct: 1825 PPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKIQSSGRVL 1883
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
IA ED G Y+CVA N+ G ++H+++ P+
Sbjct: 1884 QIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPS 1920
Score = 86.2 bits (204), Expect = 2e-16
Identities = 61/219 (27%), Positives = 96/219 (43%), Gaps = 11/219 (5%)
Query: 147 DAGDYVC-QISDRVARDQVHTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNPV 203
D G+Y C I+ + ++ V VPPS++ S V R G + LEC + P
Sbjct: 3029 DGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPP 3088
Query: 204 PTVTWHR----LNDSS--SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P +TW++ + +S+ L +G L + + E G Y C N G F L V
Sbjct: 3089 PVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDD-KNFHLNV 3147
Query: 258 LYPPEIT-VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP I ER + L C PP ++W +N + S+ + +
Sbjct: 3148 YVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGS 3207
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L IA Q D GNY+C+A N G+A+++ +S + P+
Sbjct: 3208 KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPS 3246
Score = 84.6 bits (200), Expect = 7e-16
Identities = 62/214 (28%), Positives = 93/214 (43%), Gaps = 13/214 (6%)
Query: 142 RMIFQDAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
R+ +D+G YVC + V + + V V PP + + + GG A+L C G
Sbjct: 4317 RVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL-GGNAILNCEVKG 4375
Query: 201 NPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
+P PT+ W+R ++ +LG G L + G Y C N G V
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQLGNG-SLAIYGTVNEDAGDYTCVATNEAG-VVERSMS 4433
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
L + PP IT+E G + L C +P ++W + +S +RV + S
Sbjct: 4434 LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL---S 4490
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
N++L IAD Q ED + CVA N +G V V
Sbjct: 4491 NNSLYIADAQKEDTSEFECVARNLMGSVLVRVPV 4524
Score = 82.6 bits (195), Expect = 3e-15
Identities = 57/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 128 TRRITSEQHGNTN--FRMIFQDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHV 184
T RI +G+T + + D G Y C ++ D++ + V V P++R + +
Sbjct: 3292 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEK 3351
Query: 185 TARRGGAAV-LECRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVY 237
++ +ECRA G P P + W + L+ L G +++ R + VY
Sbjct: 3352 LMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVY 3411
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWY 295
C N G + LQV PP + ++ + +G + C P ++W
Sbjct: 3412 TCVASNRAGVDN-KHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWL 3470
Query: 296 QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
++ PL +T+S G LL A+ ED G Y+C+A N G +H
Sbjct: 3471 RDGQPLGLDAHLTVSTHGMVLQLLKAET--EDSGKYTCIASNEAGEVSKH 3518
Score = 82.2 bits (194), Expect = 4e-15
Identities = 61/210 (29%), Positives = 93/210 (44%), Gaps = 15/210 (7%)
Query: 146 QDAGDYVCQISDRVARDQV-HTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNP 202
+DAG Y C + D + + V VLVPP ++ S VT +A++EC ++G+P
Sbjct: 2841 EDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSP 2900
Query: 203 VPTVTWHR-----LNDSSSR-LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P +W + L D + L G LQ+ + G Y C +N G F L
Sbjct: 2901 APRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGS-AKKYFNLN 2959
Query: 257 VLYPPEITVERSWVHTG--EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP + +S T F L C V PP ++SW +N P+ + + G
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNF-ISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGG- 3017
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARR 344
TL I + D G Y+C+A N G +++
Sbjct: 3018 -RTLQIIRAKVSDGGEYTCIAINQAGESKK 3046
Score = 81.0 bits (191), Expect = 9e-15
Identities = 60/200 (30%), Positives = 85/200 (42%), Gaps = 13/200 (6%)
Query: 148 AGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
AG Y C + H T+ V PP ++ P HV +L C A G P P +
Sbjct: 3962 AGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNN--PILLPCEATGTPSPFI 4019
Query: 207 TWHR----LNDSSSRLGEGPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
TW + +N S P LQ+SR R G Y C N G + + +L V P
Sbjct: 4020 TWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGT-ALGKIKLNVQVP 4078
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I+ L C PP +++W+++ + S R + + GS L I
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGS---LQI 4135
Query: 321 ADVQPEDFGNYSCVADNSLG 340
A VQP D G+Y+C+A N G
Sbjct: 4136 AFVQPGDAGHYTCMAANVAG 4155
Score = 76.6 bits (180), Expect = 2e-13
Identities = 79/315 (25%), Positives = 125/315 (39%), Gaps = 31/315 (9%)
Query: 84 YNLQITDVGPQIR---YTVDVTIYENSETSVALAILGATGHTNVW-----ETTRRITSEQ 135
YNL++ V P I+ +V++ N T++ + G +W + T T +
Sbjct: 1351 YNLKV-HVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQT 1409
Query: 136 HGNTNFRMIF----QDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGG 190
N +F +DAG Y C+ + Q + ++VLVPP++ + V+
Sbjct: 1410 VNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNR 1469
Query: 191 AAVLECRAAGNPVPTVTWHR------LNDSS-SRLGEGPQLQLSRLERHHGGVYACTVDN 243
LEC+ G P P + W + L D + L G L L R+ G Y CTV N
Sbjct: 1470 DVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSN 1529
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRA--ELVCTVLADPPAEVSWYQNSFPL 301
G + +L + PP I + +L C P ++WY++ P+
Sbjct: 1530 AAGKQ-AKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPI 1588
Query: 302 SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTS 359
+S + +G L I Q D Y+C N G A + HV+V P +
Sbjct: 1589 MSSSQALYIDKG--QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLA 1646
Query: 360 PPLAR---APHSYTL 371
PL + HS TL
Sbjct: 1647 TPLNKQVVIAHSLTL 1661
Score = 76.6 bits (180), Expect = 2e-13
Identities = 60/225 (26%), Positives = 93/225 (41%), Gaps = 21/225 (9%)
Query: 149 GDYVCQISDRVA-RDQVHTVEVLVPPSVR---ASPETRHVTARRGGAAVLECRAAGNPVP 204
G Y C S + + ++ V V P++ + VT L C A P
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPA 2605
Query: 205 TVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
T+TW + N + L G LQ+ + + G Y+C N G ++ ++++V
Sbjct: 2606 TITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGE-MIKHYEVKVY 2664
Query: 259 YPPEITVERSW--------VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
PP I W V L C A P A +SWY++ PL + + V ++
Sbjct: 2665 IPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIA 2724
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
A G HTL I + Q D G Y+CVA N G +V+ + P+
Sbjct: 2725 ANG--HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPS 2767
Score = 75.8 bits (178), Expect = 3e-13
Identities = 64/227 (28%), Positives = 91/227 (40%), Gaps = 18/227 (7%)
Query: 146 QDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G Y C S D + + V V VPP++ + E R +T R LEC++ P P
Sbjct: 3592 EDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 205 TVTWHRLND---SSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TW R + ++ R L G LQ++ + Y C N G EF L V
Sbjct: 3652 VITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAG-KTTREFILTVN 3710
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNHT 317
PP I + L C P ++W ++ L+ + R ++ G H
Sbjct: 3711 VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH- 3769
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARR------HVEVSGRPGPARFT 358
I D G Y C+A N+ G RR HV S PGP T
Sbjct: 3770 --IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMT 3814
Score = 75.4 bits (177), Expect = 4e-13
Identities = 62/214 (28%), Positives = 94/214 (43%), Gaps = 18/214 (8%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTV-EVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ D G Y C + T +V PP V P +VT G AVL C
Sbjct: 488 KVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPN--NVTVTPGERAVLTCLIIS 545
Query: 201 NPVPTVTWHRLNDSSSRLGEGPQ--------LQLSRLERHHGGVYACTVDNGVGPPVVTE 252
+TW R ND RL E + L+L ++ + G Y C V + G +
Sbjct: 546 AVDYNLTWQR-NDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASV 604
Query: 253 FQLQVLYPPEITV-ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA 311
F L V PP++TV ++ TG G ++C+ P +++W N + S R M++
Sbjct: 605 F-LTVQEPPKVTVMPKNQSFTG-GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTS 662
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
G TL I + P+D G Y C+A NS G +++
Sbjct: 663 DG---TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693
Score = 73.7 bits (173), Expect = 1e-12
Identities = 60/211 (28%), Positives = 88/211 (41%), Gaps = 18/211 (8%)
Query: 147 DAGDYVCQISDRVARDQVHTVE--VLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D+G Y+C ++ +A + V+ V VPP ++ P +H+ + G + C A G P+P
Sbjct: 1144 DSGMYLC-VATNIAGNVTQAVKLNVHVPPKIQRGP--KHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 205 TVTWHRLNDSSSRLGE----GPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TW + + GE P L + + G+Y C N G TE L V
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTD-ETEITLHVQ 1259
Query: 259 YPPEI-TVERSWVHTGE----GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
PP + +E + T + R E C P + W N L+ E +S
Sbjct: 1260 EPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGRE-PGISILE 1318
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
L+IA V P D G Y CVA N G R
Sbjct: 1319 DGTLLVIASVTPYDNGEYICVAVNEAGTTER 1349
Score = 73.7 bits (173), Expect = 1e-12
Identities = 56/219 (25%), Positives = 89/219 (40%), Gaps = 13/219 (5%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C +S+ + + + +PPS++ T ++ LEC G P+P
Sbjct: 1519 DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPA 1578
Query: 206 VTWHRLND---SSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+TW++ SSS+ + +G L + R + Y C V N G F + V
Sbjct: 1579 ITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAG-TAEKSFHVDVYV 1637
Query: 260 PPEITVERSWVHTGEGFRAE---LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP I + + A L C +P ++W ++ P+ A++ + + A G
Sbjct: 1638 PPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKK- 1696
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L I Q D G Y CVA + G EV PA
Sbjct: 1697 -LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPA 1734
Score = 72.9 bits (171), Expect = 2e-12
Identities = 75/332 (22%), Positives = 123/332 (37%), Gaps = 28/332 (8%)
Query: 88 ITDVGPQIRYTVDVTIYENSETSVALAILGATGHTNVWETT---------RRITSEQHGN 138
+++ P I+ +VT+ + I+ A + W+ RI + + +
Sbjct: 516 VSEPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS 575
Query: 139 TNFRMI-FQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLEC 196
+ + F DAG+Y C +S + V PP V P+ + T G + C
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTG--GSEVSIMC 633
Query: 197 RAAGNPVPTVTWHRLNDS------SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVV 250
A G P P + W +ND R+ L + G+Y C N G
Sbjct: 634 SATGYPKPKIAW-TVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQ 692
Query: 251 TEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
L+ + P++ V +S + G + C PP +V W++ L S + +
Sbjct: 693 NS-TLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIID 751
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPP--LARAPHS 368
L I + Q D G+Y+CVA N GRA + + P P +
Sbjct: 752 PLLG--LLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSN 809
Query: 369 YTLSFAVDSYPPLDELRLLYRQLAINESFQQP 400
TL V YP E + +R+L F +P
Sbjct: 810 VTLPCYVQGYP---EPTIKWRRLDNMPIFSRP 838
Score = 71.7 bits (168), Expect = 5e-12
Identities = 60/213 (28%), Positives = 90/213 (42%), Gaps = 16/213 (7%)
Query: 147 DAGDYVCQISDRVARDQVHT---VEVLVPPSVRASPETRHVTARRGGAAVLECRA-AGNP 202
D G Y+C+ ++ + Q T V LV P + SP +V G L C AGNP
Sbjct: 861 DKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVI--EGQQLTLPCTLLAGNP 918
Query: 203 VPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPP-VVTEFQLQ 256
+P W + L + + L + R++ GG Y C N G T +
Sbjct: 919 IPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH 978
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
VL P I + + T EG L C +P V W + +S S SA G++
Sbjct: 979 VL--PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSS-AKFSA-GADG 1034
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+L + E+ G Y C A N+ G A+R V+++
Sbjct: 1035 SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLT 1067
Score = 71.3 bits (167), Expect = 7e-12
Identities = 75/306 (24%), Positives = 120/306 (39%), Gaps = 31/306 (10%)
Query: 100 DVTIYENSETSVALAILGATGHTNVWETTRRITSEQHGNTNFRMI-----------FQDA 148
++T+ N +T++A G + W + + ++R++ D
Sbjct: 3812 NMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 3871
Query: 149 GDYVCQISDRVARDQVHTVE--VLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
Y C +++ A D TV+ V VPPS+ P VT + AV+ C A+G P P++
Sbjct: 3872 ATYECTVTNG-AGDDKRTVDLTVQVPPSIADEPTDFLVT--KHAPAVITCTASGVPFPSI 3928
Query: 207 TWHRLNDSSSRLGEGPQL------QLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
W + G+G ++ ++ + +H G Y C N G L V P
Sbjct: 3929 HWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGS-AHRHVTLHVHEP 3987
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I + S +H L C P ++W + ++ S R A + L I
Sbjct: 3988 PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGR--NHAVLPSGGLQI 4045
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR----APHSYTLSFAVD 376
+ ED G Y CVA N G A ++++ + P SP L TLS D
Sbjct: 4046 SRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPV--ISPHLKEYVIAVDKPITLSCEAD 4103
Query: 377 SYPPLD 382
PP D
Sbjct: 4104 GLPPPD 4109
Score = 70.9 bits (166), Expect = 1e-11
Identities = 58/209 (27%), Positives = 86/209 (41%), Gaps = 14/209 (6%)
Query: 147 DAGDYVCQISDRVAR-DQVHTVEVLVPPSVRAS-PETRHVTARRGGAAVLECRAAGNPVP 204
DA Y C S+ + + ++V + P++ S + RG + LEC G P P
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 205 TVTW----HRLNDSS--SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
TVTW H L + L EG LQL + G Y C N G ++ L V
Sbjct: 2323 TVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG-MTDKKYDLSVH 2381
Query: 259 YPPEITVER---SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
PP I + E L C P ++W+++ +P+S S V + + G
Sbjct: 2382 APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGG-- 2439
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARR 344
L + ED G Y+CV N+ G R+
Sbjct: 2440 RMLRLMQTTMEDAGQYTCVVRNAAGEERK 2468
Score = 70.9 bits (166), Expect = 1e-11
Identities = 61/210 (29%), Positives = 86/210 (40%), Gaps = 16/210 (7%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C ++ D+ ++V VPPS+ P ++T L C A G P P+
Sbjct: 3777 DTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPT--NMTVIVNVQTTLACEATGIPKPS 3834
Query: 206 VTW----HRLN----DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W H LN +S RL L + Y CTV NG G T L V
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRT-VDLTV 3893
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL-SASERVTMSARGSNH 316
PP I E + + A + CT P + W +N L + + + G+
Sbjct: 3894 QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGA-- 3951
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHV 346
+ I Q G Y+CVA N+ G A RHV
Sbjct: 3952 -IEILATQLNHAGRYTCVARNAAGSAHRHV 3980
Score = 69.7 bits (163), Expect = 2e-11
Identities = 56/201 (27%), Positives = 83/201 (41%), Gaps = 14/201 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
DAG Y C ++ T + V VPP +R++ H T A+L C A G P P
Sbjct: 4142 DAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG--HYTVNENSQAILPCVADGIPTPA 4199
Query: 206 VTWHRLND-SSSRLGEGP-----QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W + N ++ LG+ +L L + G Y C +N G T L V
Sbjct: 4200 INWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHT-VSLTVHV 4258
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
P T V +G + L C P +++W N+ + A + + L+
Sbjct: 4259 LPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAH----FDSVNGHSELV 4314
Query: 320 IADVQPEDFGNYSCVADNSLG 340
I V ED G Y C A+NS+G
Sbjct: 4315 IERVSKEDSGTYVCTAENSVG 4335
Score = 69.3 bits (162), Expect = 3e-11
Identities = 54/223 (24%), Positives = 90/223 (40%), Gaps = 14/223 (6%)
Query: 147 DAGDYVC---QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D +Y C I+ + R+ + TV V PP+++ P++ + + + VLEC A G P
Sbjct: 3686 DTANYTCVASNIAGKTTREFILTVNV--PPNIKGGPQSLVILLNK--STVLECIAEGVPT 3741
Query: 204 PTVTWHR----LNDSSSRLG--EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P +TW + L + +R E L + G Y C N G LQV
Sbjct: 3742 PRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDR-RRIDLQV 3800
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + + + L C P ++W +N L+ + S+ +
Sbjct: 3801 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS 3860
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
L+I +D Y C N G +R V+++ + P+ P
Sbjct: 3861 LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEP 3903
Score = 68.9 bits (161), Expect = 4e-11
Identities = 52/213 (24%), Positives = 94/213 (44%), Gaps = 13/213 (6%)
Query: 147 DAGDYVC-QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G+Y+C +++ ++ + ++V VPP ++ + +V+ L C G P P
Sbjct: 1332 DNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPI 1391
Query: 206 VTWHRLN----DSSS--RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W++ N +SS+ + G L+L R G Y+C N G F + VL
Sbjct: 1392 IMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTS-QKYFNIDVLV 1450
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNH 316
PP I T + V L C V P ++ W+++ PL + V + RG
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG--Q 1508
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
L + + + D G Y C N+ G+ + ++++
Sbjct: 1509 VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 1541
Score = 68.1 bits (159), Expect = 7e-11
Identities = 55/211 (26%), Positives = 81/211 (38%), Gaps = 15/211 (7%)
Query: 147 DAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D+G+Y C S+ + Q + + + VPPSV + V+ G L C A G P P
Sbjct: 3218 DSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 206 VTWHR-----LNDSSSRL---GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W + + + R+ G L + G Y C N G F L V
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI-FNLNV 3336
Query: 258 LYPPEITV---ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
P I E + T + C PP +++W +N PL S + + A G
Sbjct: 3337 YVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG- 3395
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
+ I Q D Y+CVA N G +H
Sbjct: 3396 -QVIRIVRAQVSDVAVYTCVASNRAGVDNKH 3425
Score = 67.7 bits (158), Expect = 9e-11
Identities = 70/277 (25%), Positives = 110/277 (39%), Gaps = 41/277 (14%)
Query: 100 DVTIYENSETSVALAILGATGHTNVW-------ETTRRITSEQHGNTNFRMIFQD--AGD 150
DVT+ NS TS+ T W E+ R I G T + Q+ AG
Sbjct: 2584 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGR 2643
Query: 151 YVCQISDRVARDQVH-TVEVLVPPSVRASP------ETRHVTARRGGAAVLECRAAGNPV 203
Y C ++ H V+V +PP + + V + LEC A P
Sbjct: 2644 YSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPS 2703
Query: 204 PTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+++W++ +D + G LQ+ + G Y C N G + +F + +
Sbjct: 2704 ASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL-DFDVNI 2762
Query: 258 LYPPEITVERSW-----VHTGEGFRAE---------LVCTVLADPPAEVSWYQNSFPLSA 303
PP ++ W + TG A+ L C A PP ++WY++ PL++
Sbjct: 2763 QVPPSF--QKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS 2820
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
S++V + G L I + ED G Y+CVA N G
Sbjct: 2821 SDKVLILPGG--RVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 66.9 bits (156), Expect = 2e-10
Identities = 69/260 (26%), Positives = 107/260 (41%), Gaps = 27/260 (10%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHV--TARRGGAA--------VLE 195
D G Y C S+ D++ V + VPPS + E ++ T R G A L
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 196 CRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPV 249
C P PT+TW++ +D L G LQ+ R + G Y C N G
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Query: 250 VTEFQLQVLYPPEITVERS----WVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE 305
+ ++ ++VL PP I S V A + C P SW ++ PL +
Sbjct: 2859 L-QYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD 2917
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF--TSPPLA 363
+ G L I + Q D G Y CVA+N+ G A+++ ++ P+ S L
Sbjct: 2918 HHKFLSNG--RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLT 2975
Query: 364 RAPHSY-TLSFAVDSYPPLD 382
+++ +L+ V +PP D
Sbjct: 2976 VVVNNFISLTCEVSGFPPPD 2995
Score = 64.1 bits (149), Expect = 1e-09
Identities = 61/235 (25%), Positives = 99/235 (42%), Gaps = 21/235 (8%)
Query: 131 ITSEQHGNTNF-RMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRG 189
IT G+ + R+ QD G+Y C ++ VA T V+V + ++ G
Sbjct: 937 ITVRSDGSLHIERVQLQDGGEYTC-VASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEG 995
Query: 190 GAAVLECRAAGNPVPTVTWHR----LNDSSSRLGEGPQLQLSRLER--HHGGVYACTVDN 243
L C+A+GNP P+V W + ++ SS++ G L + G Y CT N
Sbjct: 996 IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGE--------GFRAELVCTVLADPPAEVSWY 295
G + QL V P + ++ + + G L C V + PP ++W
Sbjct: 1056 TAGY-AKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 1114
Query: 296 QNSFPLSA-SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+ + +S S R T GS + I + + D G Y CVA N G + V+++
Sbjct: 1115 KETQLISPFSPRHTFLPSGS---MKITETRTSDSGMYLCVATNIAGNVTQAVKLN 1166
Score = 60.1 bits (139), Expect = 2e-08
Identities = 60/248 (24%), Positives = 95/248 (38%), Gaps = 17/248 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C + Q + V VPP++ E ++V+ A L C++ P PT
Sbjct: 2077 DTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMG--EEQNVSVLISQAVELLCQSDAIPPPT 2134
Query: 206 VTWHR-----LNDSSSRLGEGPQ-LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+TW + L + E L++ + G Y C N G + + +
Sbjct: 2135 LTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK-TEKNYNVNIWV 2193
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + E + + EG L+C PP + W + P+ +
Sbjct: 2194 PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQ 2253
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTSPP---LARAPHSYTLS 372
L I+ + D YSCVA N G A++ +++V RP S P + S +L
Sbjct: 2254 LQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLE 2313
Query: 373 FAVDSYPP 380
V PP
Sbjct: 2314 CEVQGIPP 2321
Score = 58.0 bits (134), Expect = 7e-08
Identities = 61/229 (26%), Positives = 92/229 (40%), Gaps = 14/229 (6%)
Query: 146 QDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C S+ D Q T+ + P + V G V+EC+ +G P P
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVAL--GDITVMECKTSGIPPP 731
Query: 205 TVTWHRLN---DSSSRLGEGPQLQLSRLERHH---GGVYACTVDNGVGPPVVTEFQLQVL 258
V W + + S+ L P L L +++ G Y C N G + L V
Sbjct: 732 QVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGR-ATGKITLDVG 790
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ-NSFPL-SASERVTMSARGSNH 316
PP E + V G L C V P + W + ++ P+ S V+ ++
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRH--VEVSGRPGPARFTSPPLA 363
L I ++ D G Y C A+N G+ + V V+G P SP +A
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVA 899
Score = 48.8 bits (111), Expect = 4e-05
Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 126 ETTRRITSEQHGNTN-FRMIFQDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRH 183
E + RI +G+ + + +DAGDY C ++ ++ ++ + PP + P
Sbjct: 4391 EISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETV 4450
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLNDSSS 216
+ A GG +L C+A G P PT+TW R S S
Sbjct: 4451 INA--GGKIILNCQATGEPQPTITWSRQGHSIS 4481
>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
Length = 5635
Score = 98.3 bits (234), Expect = 5e-20
Identities = 61/215 (28%), Positives = 97/215 (45%), Gaps = 15/215 (6%)
Query: 146 QDAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C + + ++ + + VLVPP + V + + L C GNPVP
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2509
Query: 205 TVTWHR----LNDSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TWH+ L + + + G LQ++ ++ H G Y C + G F L V
Sbjct: 2510 EITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHK-SRSFSLNVF 2568
Query: 259 YPPEITVERSWVHTGE-----GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
P I S + + LVC + PPA ++W+++ PL ++ + + G
Sbjct: 2569 VSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGG 2628
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
TL I + Q ++ G YSCVA N G +H EV
Sbjct: 2629 --RTLQILNAQEDNAGRYSCVATNEAGEMIKHYEV 2661
Score = 96.3 bits (229), Expect = 2e-19
Identities = 66/222 (29%), Positives = 100/222 (45%), Gaps = 15/222 (6%)
Query: 146 QDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
QD G Y C+ ++ + ++ + V + VPP++ S E +T G L C ++G P P
Sbjct: 2167 QDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPP 2226
Query: 205 TVTWHR-----LNDSSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
+ W + L DS R L G QLQ+S E+ +Y+C N G E+ LQ
Sbjct: 2227 NLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT-AKKEYNLQ 2285
Query: 257 VLYPPEITVERSW---VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
V P IT S + G L C V PP V+W ++ PL ++ V + G
Sbjct: 2286 VYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEG 2345
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
H L + ++ D G Y CVA N G + ++S P+
Sbjct: 2346 --HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPS 2385
Score = 91.9 bits (218), Expect = 5e-18
Identities = 57/214 (26%), Positives = 95/214 (44%), Gaps = 9/214 (4%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
+ + +DAG Y C ++ Q H + V PPS+ + + + T LEC+AAG
Sbjct: 1887 KTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAG 1946
Query: 201 NPVPTVTWHR----LNDSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
NPVP +TW++ L+ S+S L G + + + G+Y C N G + +
Sbjct: 1947 NPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELF-YS 2005
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
LQV P I+ + V L C P ++W ++ P+S+ +
Sbjct: 2006 LQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSG 2064
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
L + Q D G Y+CVA N+ G +R +++
Sbjct: 2065 GRILALTSAQISDTGRYTCVAVNAAGEKQRDIDL 2098
Score = 87.8 bits (208), Expect = 8e-17
Identities = 67/211 (31%), Positives = 92/211 (43%), Gaps = 17/211 (8%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G YVC+ + RD + + V VPPS+ PE + L C A G P PT
Sbjct: 3124 DTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG-PEREVIVETISNPVTLTCDATGIPPPT 3182
Query: 206 VTW----HRLNDSSSR----LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W R+ +S S L G +LQ++R + G Y C N G F L +
Sbjct: 3183 IAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYF-LSI 3241
Query: 258 LYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA--SERVTMSARG 313
PP + S V G ELVC P + W ++ P+++ +ER+ +SA G
Sbjct: 3242 QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG 3301
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
S TL I D G Y+CVA N G R
Sbjct: 3302 S--TLNIYGALTSDTGKYTCVATNPAGEEDR 3330
Score = 87.4 bits (207), Expect = 1e-16
Identities = 59/203 (29%), Positives = 88/203 (43%), Gaps = 12/203 (5%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D Y C S+R D H ++V PP++ S T +T +G + + C G P P+
Sbjct: 3407 DVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPS 3466
Query: 206 VTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W R L+ + G LQL + E G Y C N G V F L+VL
Sbjct: 3467 MAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG-EVSKHFILKVLE 3525
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + E + EL C P +++W ++ PL +++V G
Sbjct: 3526 PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQV--QTLGGGEV 3583
Query: 318 LLIADVQPEDFGNYSCVADNSLG 340
L I+ Q ED G Y+C+A + G
Sbjct: 3584 LRISTAQVEDTGRYTCLASSPAG 3606
Score = 86.6 bits (205), Expect = 2e-16
Identities = 73/280 (26%), Positives = 117/280 (41%), Gaps = 22/280 (7%)
Query: 91 VGPQIRYTVD-VTIYENSETSVALAILGATGHTNVWETTR--------RITSEQHGNTNF 141
V P+IR T T+ ENS+ + G W+ + T+E +G
Sbjct: 4167 VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELIL 4226
Query: 142 R-MIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ +D+G Y C +++ A + HTV + V + V+ +G L C+A G
Sbjct: 4227 ENVVLEDSGFYTC-VANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATG 4285
Query: 201 NPVPTVTWHRLND----SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P+P +TW N+ + +L + R+ + G Y CT +N VG F +
Sbjct: 4286 IPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGF-VY 4344
Query: 257 VLYPPEITVE--RSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP + +W+ G A L C V DP + W + + S R+ GS
Sbjct: 4345 VKEPPVFKGDYPSNWIEPLGG-NAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGS 4403
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
L I ED G+Y+CVA N G R + ++ + P
Sbjct: 4404 ---LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 86.2 bits (204), Expect = 2e-16
Identities = 54/217 (24%), Positives = 96/217 (44%), Gaps = 10/217 (4%)
Query: 147 DAGDYVCQISDRVARDQV-HTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C + ++ + V+VLVPP++ ET + L+C G+P PT
Sbjct: 1706 DRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPT 1765
Query: 206 VTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W + D L G +L +++ + + G+Y C N G EF++ V
Sbjct: 1766 IMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH-KKEFEVTVHV 1824
Query: 260 PPEITVERSWVHTGEGFR-AELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP I ++ L C P ++W ++ P++ ++ + + S L
Sbjct: 1825 PPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKIQSSGRVL 1883
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
IA ED G Y+CVA N+ G ++H+++ P+
Sbjct: 1884 QIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPS 1920
Score = 86.2 bits (204), Expect = 2e-16
Identities = 61/219 (27%), Positives = 96/219 (43%), Gaps = 11/219 (5%)
Query: 147 DAGDYVC-QISDRVARDQVHTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNPV 203
D G+Y C I+ + ++ V VPPS++ S V R G + LEC + P
Sbjct: 3029 DGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPP 3088
Query: 204 PTVTWHR----LNDSS--SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P +TW++ + +S+ L +G L + + E G Y C N G F L V
Sbjct: 3089 PVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDD-KNFHLNV 3147
Query: 258 LYPPEIT-VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP I ER + L C PP ++W +N + S+ + +
Sbjct: 3148 YVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGS 3207
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L IA Q D GNY+C+A N G+A+++ +S + P+
Sbjct: 3208 KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPS 3246
Score = 84.6 bits (200), Expect = 7e-16
Identities = 62/214 (28%), Positives = 93/214 (43%), Gaps = 13/214 (6%)
Query: 142 RMIFQDAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
R+ +D+G YVC + V + + V V PP + + + GG A+L C G
Sbjct: 4317 RVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL-GGNAILNCEVKG 4375
Query: 201 NPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
+P PT+ W+R ++ +LG G L + G Y C N G V
Sbjct: 4376 DPTPTIQWNRKGVDIEISHRIRQLGNG-SLAIYGTVNEDAGDYTCVATNEAG-VVERSMS 4433
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
L + PP IT+E G + L C +P ++W + +S +RV + S
Sbjct: 4434 LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL---S 4490
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
N++L IAD Q ED + CVA N +G V V
Sbjct: 4491 NNSLYIADAQKEDTSEFECVARNLMGSVLVRVPV 4524
Score = 82.6 bits (195), Expect = 3e-15
Identities = 57/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 128 TRRITSEQHGNTN--FRMIFQDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHV 184
T RI +G+T + + D G Y C ++ D++ + V V P++R + +
Sbjct: 3292 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEK 3351
Query: 185 TARRGGAAV-LECRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVY 237
++ +ECRA G P P + W + L+ L G +++ R + VY
Sbjct: 3352 LMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVY 3411
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWY 295
C N G + LQV PP + ++ + +G + C P ++W
Sbjct: 3412 TCVASNRAGVDN-KHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWL 3470
Query: 296 QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
++ PL +T+S G LL A+ ED G Y+C+A N G +H
Sbjct: 3471 RDGQPLGLDAHLTVSTHGMVLQLLKAET--EDSGKYTCIASNEAGEVSKH 3518
Score = 82.2 bits (194), Expect = 4e-15
Identities = 61/210 (29%), Positives = 93/210 (44%), Gaps = 15/210 (7%)
Query: 146 QDAGDYVCQISDRVARDQV-HTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNP 202
+DAG Y C + D + + V VLVPP ++ S VT +A++EC ++G+P
Sbjct: 2841 EDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSP 2900
Query: 203 VPTVTWHR-----LNDSSSR-LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P +W + L D + L G LQ+ + G Y C +N G F L
Sbjct: 2901 APRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGS-AKKYFNLN 2959
Query: 257 VLYPPEITVERSWVHTG--EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP + +S T F L C V PP ++SW +N P+ + + G
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNF-ISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGG- 3017
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARR 344
TL I + D G Y+C+A N G +++
Sbjct: 3018 -RTLQIIRAKVSDGGEYTCIAINQAGESKK 3046
Score = 81.0 bits (191), Expect = 9e-15
Identities = 60/200 (30%), Positives = 85/200 (42%), Gaps = 13/200 (6%)
Query: 148 AGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
AG Y C + H T+ V PP ++ P HV +L C A G P P +
Sbjct: 3962 AGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNN--PILLPCEATGTPSPFI 4019
Query: 207 TWHR----LNDSSSRLGEGPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
TW + +N S P LQ+SR R G Y C N G + + +L V P
Sbjct: 4020 TWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGT-ALGKIKLNVQVP 4078
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I+ L C PP +++W+++ + S R + + GS L I
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGS---LQI 4135
Query: 321 ADVQPEDFGNYSCVADNSLG 340
A VQP D G+Y+C+A N G
Sbjct: 4136 AFVQPGDAGHYTCMAANVAG 4155
Score = 76.6 bits (180), Expect = 2e-13
Identities = 79/315 (25%), Positives = 125/315 (39%), Gaps = 31/315 (9%)
Query: 84 YNLQITDVGPQIR---YTVDVTIYENSETSVALAILGATGHTNVW-----ETTRRITSEQ 135
YNL++ V P I+ +V++ N T++ + G +W + T T +
Sbjct: 1351 YNLKV-HVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQT 1409
Query: 136 HGNTNFRMIF----QDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGG 190
N +F +DAG Y C+ + Q + ++VLVPP++ + V+
Sbjct: 1410 VNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNR 1469
Query: 191 AAVLECRAAGNPVPTVTWHR------LNDSS-SRLGEGPQLQLSRLERHHGGVYACTVDN 243
LEC+ G P P + W + L D + L G L L R+ G Y CTV N
Sbjct: 1470 DVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSN 1529
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRA--ELVCTVLADPPAEVSWYQNSFPL 301
G + +L + PP I + +L C P ++WY++ P+
Sbjct: 1530 AAGKQ-AKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPI 1588
Query: 302 SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTS 359
+S + +G L I Q D Y+C N G A + HV+V P +
Sbjct: 1589 MSSSQALYIDKG--QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLA 1646
Query: 360 PPLAR---APHSYTL 371
PL + HS TL
Sbjct: 1647 TPLNKQVVIAHSLTL 1661
Score = 76.6 bits (180), Expect = 2e-13
Identities = 60/225 (26%), Positives = 93/225 (41%), Gaps = 21/225 (9%)
Query: 149 GDYVCQISDRVA-RDQVHTVEVLVPPSVR---ASPETRHVTARRGGAAVLECRAAGNPVP 204
G Y C S + + ++ V V P++ + VT L C A P
Sbjct: 2546 GRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPA 2605
Query: 205 TVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
T+TW + N + L G LQ+ + + G Y+C N G ++ ++++V
Sbjct: 2606 TITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGE-MIKHYEVKVY 2664
Query: 259 YPPEITVERSW--------VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
PP I W V L C A P A +SWY++ PL + + V ++
Sbjct: 2665 IPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIA 2724
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
A G HTL I + Q D G Y+CVA N G +V+ + P+
Sbjct: 2725 ANG--HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPS 2767
Score = 75.8 bits (178), Expect = 3e-13
Identities = 64/227 (28%), Positives = 91/227 (40%), Gaps = 18/227 (7%)
Query: 146 QDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G Y C S D + + V V VPP++ + E R +T R LEC++ P P
Sbjct: 3592 EDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPP 3651
Query: 205 TVTWHRLND---SSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TW R + ++ R L G LQ++ + Y C N G EF L V
Sbjct: 3652 VITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAG-KTTREFILTVN 3710
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNHT 317
PP I + L C P ++W ++ L+ + R ++ G H
Sbjct: 3711 VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH- 3769
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARR------HVEVSGRPGPARFT 358
I D G Y C+A N+ G RR HV S PGP T
Sbjct: 3770 --IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMT 3814
Score = 75.4 bits (177), Expect = 4e-13
Identities = 62/214 (28%), Positives = 94/214 (43%), Gaps = 18/214 (8%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTV-EVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ D G Y C + T +V PP V P +VT G AVL C
Sbjct: 488 KVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPN--NVTVTPGERAVLTCLIIS 545
Query: 201 NPVPTVTWHRLNDSSSRLGEGPQ--------LQLSRLERHHGGVYACTVDNGVGPPVVTE 252
+TW R ND RL E + L+L ++ + G Y C V + G +
Sbjct: 546 AVDYNLTWQR-NDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASV 604
Query: 253 FQLQVLYPPEITV-ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA 311
F L V PP++TV ++ TG G ++C+ P +++W N + S R M++
Sbjct: 605 F-LTVQEPPKVTVMPKNQSFTG-GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTS 662
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
G TL I + P+D G Y C+A NS G +++
Sbjct: 663 DG---TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693
Score = 73.7 bits (173), Expect = 1e-12
Identities = 60/211 (28%), Positives = 88/211 (41%), Gaps = 18/211 (8%)
Query: 147 DAGDYVCQISDRVARDQVHTVE--VLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D+G Y+C ++ +A + V+ V VPP ++ P +H+ + G + C A G P+P
Sbjct: 1144 DSGMYLC-VATNIAGNVTQAVKLNVHVPPKIQRGP--KHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 205 TVTWHRLNDSSSRLGE----GPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TW + + GE P L + + G+Y C N G TE L V
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTD-ETEITLHVQ 1259
Query: 259 YPPEI-TVERSWVHTGE----GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
PP + +E + T + R E C P + W N L+ E +S
Sbjct: 1260 EPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGRE-PGISILE 1318
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
L+IA V P D G Y CVA N G R
Sbjct: 1319 DGTLLVIASVTPYDNGEYICVAVNEAGTTER 1349
Score = 73.7 bits (173), Expect = 1e-12
Identities = 56/219 (25%), Positives = 89/219 (40%), Gaps = 13/219 (5%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C +S+ + + + +PPS++ T ++ LEC G P+P
Sbjct: 1519 DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPA 1578
Query: 206 VTWHRLND---SSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+TW++ SSS+ + +G L + R + Y C V N G F + V
Sbjct: 1579 ITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAG-TAEKSFHVDVYV 1637
Query: 260 PPEITVERSWVHTGEGFRAE---LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP I + + A L C +P ++W ++ P+ A++ + + A G
Sbjct: 1638 PPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKK- 1696
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L I Q D G Y CVA + G EV PA
Sbjct: 1697 -LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPA 1734
Score = 72.9 bits (171), Expect = 2e-12
Identities = 75/332 (22%), Positives = 123/332 (37%), Gaps = 28/332 (8%)
Query: 88 ITDVGPQIRYTVDVTIYENSETSVALAILGATGHTNVWETT---------RRITSEQHGN 138
+++ P I+ +VT+ + I+ A + W+ RI + + +
Sbjct: 516 VSEPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS 575
Query: 139 TNFRMI-FQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLEC 196
+ + F DAG+Y C +S + V PP V P+ + T G + C
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTG--GSEVSIMC 633
Query: 197 RAAGNPVPTVTWHRLNDS------SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVV 250
A G P P + W +ND R+ L + G+Y C N G
Sbjct: 634 SATGYPKPKIAW-TVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQ 692
Query: 251 TEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
L+ + P++ V +S + G + C PP +V W++ L S + +
Sbjct: 693 NS-TLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIID 751
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPP--LARAPHS 368
L I + Q D G+Y+CVA N GRA + + P P +
Sbjct: 752 PLLG--LLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSN 809
Query: 369 YTLSFAVDSYPPLDELRLLYRQLAINESFQQP 400
TL V YP E + +R+L F +P
Sbjct: 810 VTLPCYVQGYP---EPTIKWRRLDNMPIFSRP 838
Score = 71.7 bits (168), Expect = 5e-12
Identities = 60/213 (28%), Positives = 90/213 (42%), Gaps = 16/213 (7%)
Query: 147 DAGDYVCQISDRVARDQVHT---VEVLVPPSVRASPETRHVTARRGGAAVLECRA-AGNP 202
D G Y+C+ ++ + Q T V LV P + SP +V G L C AGNP
Sbjct: 861 DKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVI--EGQQLTLPCTLLAGNP 918
Query: 203 VPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPP-VVTEFQLQ 256
+P W + L + + L + R++ GG Y C N G T +
Sbjct: 919 IPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH 978
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
VL P I + + T EG L C +P V W + +S S SA G++
Sbjct: 979 VL--PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSS-AKFSA-GADG 1034
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+L + E+ G Y C A N+ G A+R V+++
Sbjct: 1035 SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLT 1067
Score = 71.3 bits (167), Expect = 7e-12
Identities = 75/306 (24%), Positives = 120/306 (39%), Gaps = 31/306 (10%)
Query: 100 DVTIYENSETSVALAILGATGHTNVWETTRRITSEQHGNTNFRMI-----------FQDA 148
++T+ N +T++A G + W + + ++R++ D
Sbjct: 3812 NMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 3871
Query: 149 GDYVCQISDRVARDQVHTVE--VLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
Y C +++ A D TV+ V VPPS+ P VT + AV+ C A+G P P++
Sbjct: 3872 ATYECTVTNG-AGDDKRTVDLTVQVPPSIADEPTDFLVT--KHAPAVITCTASGVPFPSI 3928
Query: 207 TWHRLNDSSSRLGEGPQL------QLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
W + G+G ++ ++ + +H G Y C N G L V P
Sbjct: 3929 HWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGS-AHRHVTLHVHEP 3987
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I + S +H L C P ++W + ++ S R A + L I
Sbjct: 3988 PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGR--NHAVLPSGGLQI 4045
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR----APHSYTLSFAVD 376
+ ED G Y CVA N G A ++++ + P SP L TLS D
Sbjct: 4046 SRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPV--ISPHLKEYVIAVDKPITLSCEAD 4103
Query: 377 SYPPLD 382
PP D
Sbjct: 4104 GLPPPD 4109
Score = 70.9 bits (166), Expect = 1e-11
Identities = 58/209 (27%), Positives = 86/209 (41%), Gaps = 14/209 (6%)
Query: 147 DAGDYVCQISDRVAR-DQVHTVEVLVPPSVRAS-PETRHVTARRGGAAVLECRAAGNPVP 204
DA Y C S+ + + ++V + P++ S + RG + LEC G P P
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 205 TVTW----HRLNDSS--SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
TVTW H L + L EG LQL + G Y C N G ++ L V
Sbjct: 2323 TVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG-MTDKKYDLSVH 2381
Query: 259 YPPEITVER---SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
PP I + E L C P ++W+++ +P+S S V + + G
Sbjct: 2382 APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGG-- 2439
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARR 344
L + ED G Y+CV N+ G R+
Sbjct: 2440 RMLRLMQTTMEDAGQYTCVVRNAAGEERK 2468
Score = 70.9 bits (166), Expect = 1e-11
Identities = 61/210 (29%), Positives = 86/210 (40%), Gaps = 16/210 (7%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C ++ D+ ++V VPPS+ P ++T L C A G P P+
Sbjct: 3777 DTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPT--NMTVIVNVQTTLACEATGIPKPS 3834
Query: 206 VTW----HRLN----DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W H LN +S RL L + Y CTV NG G T L V
Sbjct: 3835 INWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRT-VDLTV 3893
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL-SASERVTMSARGSNH 316
PP I E + + A + CT P + W +N L + + + G+
Sbjct: 3894 QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGA-- 3951
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHV 346
+ I Q G Y+CVA N+ G A RHV
Sbjct: 3952 -IEILATQLNHAGRYTCVARNAAGSAHRHV 3980
Score = 69.7 bits (163), Expect = 2e-11
Identities = 56/201 (27%), Positives = 83/201 (41%), Gaps = 14/201 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
DAG Y C ++ T + V VPP +R++ H T A+L C A G P P
Sbjct: 4142 DAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG--HYTVNENSQAILPCVADGIPTPA 4199
Query: 206 VTWHRLND-SSSRLGEGP-----QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W + N ++ LG+ +L L + G Y C +N G T L V
Sbjct: 4200 INWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHT-VSLTVHV 4258
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
P T V +G + L C P +++W N+ + A + + L+
Sbjct: 4259 LPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAH----FDSVNGHSELV 4314
Query: 320 IADVQPEDFGNYSCVADNSLG 340
I V ED G Y C A+NS+G
Sbjct: 4315 IERVSKEDSGTYVCTAENSVG 4335
Score = 69.3 bits (162), Expect = 3e-11
Identities = 54/223 (24%), Positives = 90/223 (40%), Gaps = 14/223 (6%)
Query: 147 DAGDYVC---QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D +Y C I+ + R+ + TV V PP+++ P++ + + + VLEC A G P
Sbjct: 3686 DTANYTCVASNIAGKTTREFILTVNV--PPNIKGGPQSLVILLNK--STVLECIAEGVPT 3741
Query: 204 PTVTWHR----LNDSSSRLG--EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P +TW + L + +R E L + G Y C N G LQV
Sbjct: 3742 PRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDR-RRIDLQV 3800
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + + + L C P ++W +N L+ + S+ +
Sbjct: 3801 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS 3860
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
L+I +D Y C N G +R V+++ + P+ P
Sbjct: 3861 LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEP 3903
Score = 68.9 bits (161), Expect = 4e-11
Identities = 52/213 (24%), Positives = 94/213 (44%), Gaps = 13/213 (6%)
Query: 147 DAGDYVC-QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G+Y+C +++ ++ + ++V VPP ++ + +V+ L C G P P
Sbjct: 1332 DNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPI 1391
Query: 206 VTWHRLN----DSSS--RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W++ N +SS+ + G L+L R G Y+C N G F + VL
Sbjct: 1392 IMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTS-QKYFNIDVLV 1450
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNH 316
PP I T + V L C V P ++ W+++ PL + V + RG
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG--Q 1508
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
L + + + D G Y C N+ G+ + ++++
Sbjct: 1509 VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 1541
Score = 68.1 bits (159), Expect = 7e-11
Identities = 55/211 (26%), Positives = 81/211 (38%), Gaps = 15/211 (7%)
Query: 147 DAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D+G+Y C S+ + Q + + + VPPSV + V+ G L C A G P P
Sbjct: 3218 DSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 206 VTWHR-----LNDSSSRL---GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W + + + R+ G L + G Y C N G F L V
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI-FNLNV 3336
Query: 258 LYPPEITV---ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
P I E + T + C PP +++W +N PL S + + A G
Sbjct: 3337 YVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG- 3395
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
+ I Q D Y+CVA N G +H
Sbjct: 3396 -QVIRIVRAQVSDVAVYTCVASNRAGVDNKH 3425
Score = 67.7 bits (158), Expect = 9e-11
Identities = 70/277 (25%), Positives = 110/277 (39%), Gaps = 41/277 (14%)
Query: 100 DVTIYENSETSVALAILGATGHTNVW-------ETTRRITSEQHGNTNFRMIFQD--AGD 150
DVT+ NS TS+ T W E+ R I G T + Q+ AG
Sbjct: 2584 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGR 2643
Query: 151 YVCQISDRVARDQVH-TVEVLVPPSVRASP------ETRHVTARRGGAAVLECRAAGNPV 203
Y C ++ H V+V +PP + + V + LEC A P
Sbjct: 2644 YSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPS 2703
Query: 204 PTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+++W++ +D + G LQ+ + G Y C N G + +F + +
Sbjct: 2704 ASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL-DFDVNI 2762
Query: 258 LYPPEITVERSW-----VHTGEGFRAE---------LVCTVLADPPAEVSWYQNSFPLSA 303
PP ++ W + TG A+ L C A PP ++WY++ PL++
Sbjct: 2763 QVPPSF--QKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS 2820
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
S++V + G L I + ED G Y+CVA N G
Sbjct: 2821 SDKVLILPGG--RVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 66.9 bits (156), Expect = 2e-10
Identities = 69/260 (26%), Positives = 107/260 (41%), Gaps = 27/260 (10%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHV--TARRGGAA--------VLE 195
D G Y C S+ D++ V + VPPS + E ++ T R G A L
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 196 CRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPV 249
C P PT+TW++ +D L G LQ+ R + G Y C N G
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Query: 250 VTEFQLQVLYPPEITVERS----WVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE 305
+ ++ ++VL PP I S V A + C P SW ++ PL +
Sbjct: 2859 L-QYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD 2917
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF--TSPPLA 363
+ G L I + Q D G Y CVA+N+ G A+++ ++ P+ S L
Sbjct: 2918 HHKFLSNG--RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLT 2975
Query: 364 RAPHSY-TLSFAVDSYPPLD 382
+++ +L+ V +PP D
Sbjct: 2976 VVVNNFISLTCEVSGFPPPD 2995
Score = 64.1 bits (149), Expect = 1e-09
Identities = 61/235 (25%), Positives = 99/235 (42%), Gaps = 21/235 (8%)
Query: 131 ITSEQHGNTNF-RMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRG 189
IT G+ + R+ QD G+Y C ++ VA T V+V + ++ G
Sbjct: 937 ITVRSDGSLHIERVQLQDGGEYTC-VASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEG 995
Query: 190 GAAVLECRAAGNPVPTVTWHR----LNDSSSRLGEGPQLQLSRLER--HHGGVYACTVDN 243
L C+A+GNP P+V W + ++ SS++ G L + G Y CT N
Sbjct: 996 IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGE--------GFRAELVCTVLADPPAEVSWY 295
G + QL V P + ++ + + G L C V + PP ++W
Sbjct: 1056 TAGY-AKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 1114
Query: 296 QNSFPLSA-SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+ + +S S R T GS + I + + D G Y CVA N G + V+++
Sbjct: 1115 KETQLISPFSPRHTFLPSGS---MKITETRTSDSGMYLCVATNIAGNVTQAVKLN 1166
Score = 60.1 bits (139), Expect = 2e-08
Identities = 60/248 (24%), Positives = 95/248 (38%), Gaps = 17/248 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C + Q + V VPP++ E ++V+ A L C++ P PT
Sbjct: 2077 DTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMG--EEQNVSVLISQAVELLCQSDAIPPPT 2134
Query: 206 VTWHR-----LNDSSSRLGEGPQ-LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+TW + L + E L++ + G Y C N G + + +
Sbjct: 2135 LTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK-TEKNYNVNIWV 2193
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + E + + EG L+C PP + W + P+ +
Sbjct: 2194 PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQ 2253
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTSPP---LARAPHSYTLS 372
L I+ + D YSCVA N G A++ +++V RP S P + S +L
Sbjct: 2254 LQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLE 2313
Query: 373 FAVDSYPP 380
V PP
Sbjct: 2314 CEVQGIPP 2321
Score = 58.0 bits (134), Expect = 7e-08
Identities = 61/229 (26%), Positives = 92/229 (40%), Gaps = 14/229 (6%)
Query: 146 QDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C S+ D Q T+ + P + V G V+EC+ +G P P
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVAL--GDITVMECKTSGIPPP 731
Query: 205 TVTWHRLN---DSSSRLGEGPQLQLSRLERHH---GGVYACTVDNGVGPPVVTEFQLQVL 258
V W + + S+ L P L L +++ G Y C N G + L V
Sbjct: 732 QVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGR-ATGKITLDVG 790
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ-NSFPL-SASERVTMSARGSNH 316
PP E + V G L C V P + W + ++ P+ S V+ ++
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRH--VEVSGRPGPARFTSPPLA 363
L I ++ D G Y C A+N G+ + V V+G P SP +A
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVA 899
Score = 48.8 bits (111), Expect = 4e-05
Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 126 ETTRRITSEQHGNTN-FRMIFQDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRH 183
E + RI +G+ + + +DAGDY C ++ ++ ++ + PP + P
Sbjct: 4391 EISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETV 4450
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLNDSSS 216
+ A GG +L C+A G P PT+TW R S S
Sbjct: 4451 INA--GGKIILNCQATGEPQPTITWSRQGHSIS 4481
>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
Length = 5636
Score = 98.3 bits (234), Expect = 5e-20
Identities = 61/215 (28%), Positives = 97/215 (45%), Gaps = 15/215 (6%)
Query: 146 QDAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C + + ++ + + VLVPP + V + + L C GNPVP
Sbjct: 2451 EDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVP 2510
Query: 205 TVTWHR----LNDSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TWH+ L + + + G LQ++ ++ H G Y C + G F L V
Sbjct: 2511 EITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHK-SRSFSLNVF 2569
Query: 259 YPPEITVERSWVHTGE-----GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
P I S + + LVC + PPA ++W+++ PL ++ + + G
Sbjct: 2570 VSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGG 2629
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
TL I + Q ++ G YSCVA N G +H EV
Sbjct: 2630 --RTLQILNAQEDNAGRYSCVATNEAGEMIKHYEV 2662
Score = 95.1 bits (226), Expect = 5e-19
Identities = 66/223 (29%), Positives = 99/223 (44%), Gaps = 16/223 (7%)
Query: 146 QDAGDYVCQISDRVARDQV--HTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
QD G Y C+ ++ + + + V + VPP++ S E +T G L C ++G P
Sbjct: 2167 QDTGRYTCEATNVAGKTEKKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPP 2226
Query: 204 PTVTWHR-----LNDSSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQL 255
P + W + L DS R L G QLQ+S E+ +Y+C N G E+ L
Sbjct: 2227 PNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT-AKKEYNL 2285
Query: 256 QVLYPPEITVERSW---VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
QV P IT S + G L C V PP V+W ++ PL ++ V +
Sbjct: 2286 QVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDE 2345
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
G H L + ++ D G Y CVA N G + ++S P+
Sbjct: 2346 G--HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPS 2386
Score = 91.9 bits (218), Expect = 5e-18
Identities = 57/214 (26%), Positives = 95/214 (44%), Gaps = 9/214 (4%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
+ + +DAG Y C ++ Q H + V PPS+ + + + T LEC+AAG
Sbjct: 1887 KTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAG 1946
Query: 201 NPVPTVTWHR----LNDSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
NPVP +TW++ L+ S+S L G + + + G+Y C N G + +
Sbjct: 1947 NPVPVITWYKDNCLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELF-YS 2005
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
LQV P I+ + V L C P ++W ++ P+S+ +
Sbjct: 2006 LQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSG 2064
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
L + Q D G Y+CVA N+ G +R +++
Sbjct: 2065 GRILALTSTQISDTGRYTCVAVNAAGEKQRDIDL 2098
Score = 89.0 bits (211), Expect = 3e-17
Identities = 74/280 (26%), Positives = 118/280 (42%), Gaps = 22/280 (7%)
Query: 91 VGPQIRYTVD-VTIYENSETSVALAILGATGHTNVWETTR--------RITSEQHGNTNF 141
V P+IR T T+ ENS+ + G W+ + T+E +G
Sbjct: 4168 VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELIL 4227
Query: 142 R-MIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ +D+G Y C +++ A + HTV + V + V+ +G L C+A G
Sbjct: 4228 ENVVLEDSGFYTC-VANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATG 4286
Query: 201 NPVPTVTWHRLND----SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P+P +TW N+ + +L + R+ + G Y CT +N VG T F +
Sbjct: 4287 IPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKATGF-VY 4345
Query: 257 VLYPPEITVE--RSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP + +W+ G A L C V DP + W + + S R+ GS
Sbjct: 4346 VKEPPVFKGDYPSNWIEPLGG-NAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGS 4404
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
L I ED G+Y+CVA N G R + ++ + P
Sbjct: 4405 ---LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4441
Score = 87.8 bits (208), Expect = 8e-17
Identities = 67/211 (31%), Positives = 92/211 (43%), Gaps = 17/211 (8%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G YVC+ + RD + + V VPPS+ PE + L C A G P PT
Sbjct: 3125 DTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG-PEREVIVETISNPVTLTCDATGIPPPT 3183
Query: 206 VTW----HRLNDSSSR----LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W R+ +S S L G +LQ++R + G Y C N G F L +
Sbjct: 3184 IAWLKNYKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYF-LSI 3242
Query: 258 LYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA--SERVTMSARG 313
PP + S V G ELVC P + W ++ P+++ +ER+ +SA G
Sbjct: 3243 QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG 3302
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
S TL I D G Y+CVA N G R
Sbjct: 3303 S--TLNIYGALTSDTGKYTCVATNPAGEEDR 3331
Score = 87.4 bits (207), Expect = 1e-16
Identities = 59/203 (29%), Positives = 88/203 (43%), Gaps = 12/203 (5%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D Y C S+R D H ++V PP++ S T +T +G + + C G P P+
Sbjct: 3408 DVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPS 3467
Query: 206 VTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W R L+ + G LQL + E G Y C N G V F L+VL
Sbjct: 3468 MAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG-EVSKHFILKVLE 3526
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + E + EL C P +++W ++ PL +++V G
Sbjct: 3527 PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQV--QTLGGGEV 3584
Query: 318 LLIADVQPEDFGNYSCVADNSLG 340
L I+ Q ED G Y+C+A + G
Sbjct: 3585 LRISTAQVEDTGRYTCLASSPAG 3607
Score = 86.2 bits (204), Expect = 2e-16
Identities = 54/217 (24%), Positives = 96/217 (44%), Gaps = 10/217 (4%)
Query: 147 DAGDYVCQISDRVARDQV-HTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C + ++ + V+VLVPP++ ET + L+C G+P PT
Sbjct: 1706 DRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPT 1765
Query: 206 VTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W + D L G +L +++ + + G+Y C N G EF++ V
Sbjct: 1766 IMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH-KKEFEVTVHV 1824
Query: 260 PPEITVERSWVHTGEGFR-AELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP I ++ L C P ++W ++ P++ ++ + + S L
Sbjct: 1825 PPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKIQSSGRVL 1883
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
IA ED G Y+CVA N+ G ++H+++ P+
Sbjct: 1884 QIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPS 1920
Score = 85.4 bits (202), Expect = 4e-16
Identities = 61/219 (27%), Positives = 96/219 (43%), Gaps = 11/219 (5%)
Query: 147 DAGDYVC-QISDRVARDQVHTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNPV 203
D G+Y C I+ + ++ V VPPS++ S V R G + LEC + P
Sbjct: 3030 DGGEYTCIAINXAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPP 3089
Query: 204 PTVTWHR----LNDSS--SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P +TW++ + +S+ L +G L + + E G Y C N G F L V
Sbjct: 3090 PVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDD-KNFHLNV 3148
Query: 258 LYPPEIT-VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP I ER + L C PP ++W +N + S+ + +
Sbjct: 3149 YVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNYKRIENSDSLEVRILSGGS 3208
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L IA Q D GNY+C+A N G+A+++ +S + P+
Sbjct: 3209 KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPS 3247
Score = 83.4 bits (197), Expect = 2e-15
Identities = 60/213 (28%), Positives = 89/213 (41%), Gaps = 11/213 (5%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGN 201
R+ +D+G YVC + V + + P V + GG A+L C G+
Sbjct: 4318 RVSKEDSGTYVCTAENSVGFVKATGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGD 4377
Query: 202 PVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQL 255
P PT+ W+R ++ +LG G L + G Y C N G V L
Sbjct: 4378 PTPTIQWNRKGVDIEISHRIRQLGNG-SLAIYGTVNEDAGDYTCVATNEAG-VVERSMSL 4435
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
+ PP IT+E G + L C +P ++W + +S +RV + SN
Sbjct: 4436 TLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL---SN 4492
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
++L IAD Q ED + CVA N +G V V
Sbjct: 4493 NSLYIADAQKEDTSEFECVARNLMGSVLVRVPV 4525
Score = 81.4 bits (192), Expect = 7e-15
Identities = 61/210 (29%), Positives = 92/210 (43%), Gaps = 15/210 (7%)
Query: 146 QDAGDYVCQISDRVARDQV-HTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNP 202
+DAG Y C + D + + V VLVPP + S VT +A++EC ++G+P
Sbjct: 2842 EDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIEGANSDLPEEVTVLVNKSALIECLSSGSP 2901
Query: 203 VPTVTWHR-----LNDSSSR-LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P +W + L D + L G LQ+ + G Y C +N G F L
Sbjct: 2902 APRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGS-AKKYFNLN 2960
Query: 257 VLYPPEITVERSWVHTG--EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP + +S T F L C V PP ++SW +N P+ + + G
Sbjct: 2961 VHVPPSVIGPKSENLTVVVNNF-ISLTCEVSGFPPPDLSWLKNXQPIKLNTNTLIVPGG- 3018
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARR 344
TL I + D G Y+C+A N G +++
Sbjct: 3019 -RTLQIIRAKVSDGGEYTCIAINXAGESKK 3047
Score = 81.0 bits (191), Expect = 9e-15
Identities = 56/230 (24%), Positives = 96/230 (41%), Gaps = 15/230 (6%)
Query: 128 TRRITSEQHGNTN--FRMIFQDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHV 184
T RI +G+T + + D G Y C ++ D++ + V V P++R + +
Sbjct: 3293 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEK 3352
Query: 185 TARRGGAAV-LECRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVY 237
++ +ECR G P P + W + L+ L G +++ R + VY
Sbjct: 3353 LMTYVDTSINIECRXTGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVY 3412
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWY 295
C N G + LQV PP + ++ + +G + C P ++W
Sbjct: 3413 TCVASNRAGVDN-KHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWL 3471
Query: 296 QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
++ PL +T+S G LL A+ ED G Y+C+A N G +H
Sbjct: 3472 RDGQPLGLDAHLTVSTHGMVLQLLKAET--EDSGKYTCIASNEAGEVSKH 3519
Score = 81.0 bits (191), Expect = 9e-15
Identities = 60/200 (30%), Positives = 85/200 (42%), Gaps = 13/200 (6%)
Query: 148 AGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
AG Y C + H T+ V PP ++ P HV +L C A G P P +
Sbjct: 3963 AGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNN--PILLPCEATGTPSPFI 4020
Query: 207 TWHR----LNDSSSRLGEGPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
TW + +N S P LQ+SR R G Y C N G + + +L V P
Sbjct: 4021 TWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGT-ALGKIKLNVQVP 4079
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I+ L C PP +++W+++ + S R + + GS L I
Sbjct: 4080 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGS---LQI 4136
Query: 321 ADVQPEDFGNYSCVADNSLG 340
A VQP D G+Y+C+A N G
Sbjct: 4137 AFVQPGDAGHYTCMAANVAG 4156
Score = 77.0 bits (181), Expect = 1e-13
Identities = 66/246 (26%), Positives = 100/246 (40%), Gaps = 18/246 (7%)
Query: 141 FRMIFQDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAA 199
FR +DAG Y C+ + Q + ++VLVPP++ + + V+ LEC+
Sbjct: 1419 FRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPKEVSVVLNRDVALECQVK 1478
Query: 200 GNPVPTVTWHR------LNDSS-SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
G P P + W + L D + L G L L R+ G Y CTV N G +
Sbjct: 1479 GTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQ-AKD 1537
Query: 253 FQLQVLYPPEITVERSWVHTGEGFRA--ELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
+L + PP I + +L C P ++WY++ P+ +S +
Sbjct: 1538 IKLTIYIPPSIKGGNVTTDISVLINSLIKLECKTRGLPMPAITWYKDGQPIMSSSQALYI 1597
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTSPPLAR---A 365
+G L I Q D Y+C N G A + HV+V P + PL +
Sbjct: 1598 DKG--QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVI 1655
Query: 366 PHSYTL 371
HS TL
Sbjct: 1656 AHSLTL 1661
Score = 76.6 bits (180), Expect = 2e-13
Identities = 60/225 (26%), Positives = 93/225 (41%), Gaps = 21/225 (9%)
Query: 149 GDYVCQISDRVA-RDQVHTVEVLVPPSVR---ASPETRHVTARRGGAAVLECRAAGNPVP 204
G Y C S + + ++ V V P++ + VT L C A P
Sbjct: 2547 GRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPA 2606
Query: 205 TVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
T+TW + N + L G LQ+ + + G Y+C N G ++ ++++V
Sbjct: 2607 TITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGE-MIKHYEVKVY 2665
Query: 259 YPPEITVERSW--------VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
PP I W V L C A P A +SWY++ PL + + V ++
Sbjct: 2666 IPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIA 2725
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
A G HTL I + Q D G Y+CVA N G +V+ + P+
Sbjct: 2726 ANG--HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPS 2768
Score = 75.8 bits (178), Expect = 3e-13
Identities = 64/227 (28%), Positives = 91/227 (40%), Gaps = 18/227 (7%)
Query: 146 QDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G Y C S D + + V V VPP++ + E R +T R LEC++ P P
Sbjct: 3593 EDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPP 3652
Query: 205 TVTWHRLND---SSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TW R + ++ R L G LQ++ + Y C N G EF L V
Sbjct: 3653 VITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAG-KTTREFILTVN 3711
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNHT 317
PP I + L C P ++W ++ L+ + R ++ G H
Sbjct: 3712 VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH- 3770
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARR------HVEVSGRPGPARFT 358
I D G Y C+A N+ G RR HV S PGP T
Sbjct: 3771 --IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMT 3815
Score = 75.4 bits (177), Expect = 4e-13
Identities = 62/214 (28%), Positives = 94/214 (43%), Gaps = 18/214 (8%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTV-EVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ D G Y C + T +V PP V P +VT G AVL C
Sbjct: 488 KVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPN--NVTVTPGERAVLTCLIIS 545
Query: 201 NPVPTVTWHRLNDSSSRLGEGPQ--------LQLSRLERHHGGVYACTVDNGVGPPVVTE 252
+TW R ND RL E + L+L ++ + G Y C V + G +
Sbjct: 546 AVDYNLTWQR-NDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASV 604
Query: 253 FQLQVLYPPEITV-ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA 311
F L V PP++TV ++ TG G ++C+ P +++W N + S R M++
Sbjct: 605 F-LTVQEPPKVTVMPKNQSFTG-GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTS 662
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
G TL I + P+D G Y C+A NS G +++
Sbjct: 663 DG---TLFIKNAAPKDAGIYGCLASNSAGTDKQN 693
Score = 73.7 bits (173), Expect = 1e-12
Identities = 60/211 (28%), Positives = 88/211 (41%), Gaps = 18/211 (8%)
Query: 147 DAGDYVCQISDRVARDQVHTVE--VLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D+G Y+C ++ +A + V+ V VPP ++ P +H+ + G + C A G P+P
Sbjct: 1144 DSGMYLC-VATNIAGNVTQAVKLNVHVPPKIQRGP--KHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 205 TVTWHRLNDSSSRLGE----GPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TW + + GE P L + + G+Y C N G TE L V
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTD-ETEITLHVQ 1259
Query: 259 YPPEI-TVERSWVHTGE----GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
PP + +E + T + R E C P + W N L+ E +S
Sbjct: 1260 EPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGRE-PGISILE 1318
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
L+IA V P D G Y CVA N G R
Sbjct: 1319 EGTLLVIASVTPYDNGEYICVAVNEAGTTER 1349
Score = 73.3 bits (172), Expect = 2e-12
Identities = 60/213 (28%), Positives = 91/213 (42%), Gaps = 16/213 (7%)
Query: 147 DAGDYVCQISDRVARDQVHT---VEVLVPPSVRASPETRHVTARRGGAAVLECRA-AGNP 202
D G Y+C+ ++ + Q T V LV P + SP +V G L C AGNP
Sbjct: 861 DKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVI--EGQQLTLPCTLLAGNP 918
Query: 203 VPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPP-VVTEFQLQ 256
+P W + L + + L + R++ GG Y C N G T +
Sbjct: 919 IPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH 978
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
VL P I + + T EG L C +P V W + +S S SA G++
Sbjct: 979 VL--PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSS-AKFSA-GADG 1034
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+L + + E+ G Y C A N+ G A+R V+++
Sbjct: 1035 SLYVVSPEGEESGEYVCTATNTAGYAKRKVQLT 1067
Score = 73.3 bits (172), Expect = 2e-12
Identities = 56/219 (25%), Positives = 89/219 (40%), Gaps = 13/219 (5%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C +S+ + + + +PPS++ T ++ LEC+ G P+P
Sbjct: 1519 DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECKTRGLPMPA 1578
Query: 206 VTWHRLND---SSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+TW++ SSS+ + +G L + R + Y C V N G F + V
Sbjct: 1579 ITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAG-TAEKSFHVDVYV 1637
Query: 260 PPEITVERSWVHTGEGFRAE---LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP I + + A L C +P ++W ++ P+ A++ + A G
Sbjct: 1638 PPMIEGNLATPLNKQVVIAHSLTLECNAAGNPSPILTWLKDGVPVKANDNFRIEAGGKK- 1696
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L I Q D G Y CVA + G EV PA
Sbjct: 1697 -LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPA 1734
Score = 72.9 bits (171), Expect = 2e-12
Identities = 75/332 (22%), Positives = 123/332 (37%), Gaps = 28/332 (8%)
Query: 88 ITDVGPQIRYTVDVTIYENSETSVALAILGATGHTNVWETT---------RRITSEQHGN 138
+++ P I+ +VT+ + I+ A + W+ RI + + +
Sbjct: 516 VSEPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS 575
Query: 139 TNFRMI-FQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLEC 196
+ + F DAG+Y C +S + V PP V P+ + T G + C
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTG--GSEVSIMC 633
Query: 197 RAAGNPVPTVTWHRLNDS------SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVV 250
A G P P + W +ND R+ L + G+Y C N G
Sbjct: 634 SATGYPKPKIAW-TVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQ 692
Query: 251 TEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
L+ + P++ V +S + G + C PP +V W++ L S + +
Sbjct: 693 NS-TLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIID 751
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPP--LARAPHS 368
L I + Q D G+Y+CVA N GRA + + P P +
Sbjct: 752 PLLG--LLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSN 809
Query: 369 YTLSFAVDSYPPLDELRLLYRQLAINESFQQP 400
TL V YP E + +R+L F +P
Sbjct: 810 VTLPCYVQGYP---EPTIKWRRLDNMPIFSRP 838
Score = 71.3 bits (167), Expect = 7e-12
Identities = 75/306 (24%), Positives = 120/306 (39%), Gaps = 31/306 (10%)
Query: 100 DVTIYENSETSVALAILGATGHTNVWETTRRITSEQHGNTNFRMI-----------FQDA 148
++T+ N +T++A G + W + + ++R++ D
Sbjct: 3813 NMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 3872
Query: 149 GDYVCQISDRVARDQVHTVE--VLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
Y C +++ A D TV+ V VPPS+ P VT + AV+ C A+G P P++
Sbjct: 3873 ATYECTVTNG-AGDDKRTVDLTVQVPPSIADEPTDFLVT--KHAPAVITCTASGVPFPSI 3929
Query: 207 TWHRLNDSSSRLGEGPQL------QLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
W + G+G ++ ++ + +H G Y C N G L V P
Sbjct: 3930 HWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGS-AHRHVTLHVHEP 3988
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I + S +H L C P ++W + ++ S R A + L I
Sbjct: 3989 PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGR--NHAVLPSGGLQI 4046
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR----APHSYTLSFAVD 376
+ ED G Y CVA N G A ++++ + P SP L TLS D
Sbjct: 4047 SRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPV--ISPHLKEYVIAVDKPITLSCEAD 4104
Query: 377 SYPPLD 382
PP D
Sbjct: 4105 GLPPPD 4110
Score = 70.9 bits (166), Expect = 1e-11
Identities = 61/210 (29%), Positives = 86/210 (40%), Gaps = 16/210 (7%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C ++ D+ ++V VPPS+ P ++T L C A G P P+
Sbjct: 3778 DTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPT--NMTVIVNVQTTLACEATGIPKPS 3835
Query: 206 VTW----HRLN----DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W H LN +S RL L + Y CTV NG G T L V
Sbjct: 3836 INWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRT-VDLTV 3894
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL-SASERVTMSARGSNH 316
PP I E + + A + CT P + W +N L + + + G+
Sbjct: 3895 QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGA-- 3952
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHV 346
+ I Q G Y+CVA N+ G A RHV
Sbjct: 3953 -IEILATQLNHAGRYTCVARNAAGSAHRHV 3981
Score = 69.7 bits (163), Expect = 2e-11
Identities = 58/209 (27%), Positives = 85/209 (40%), Gaps = 14/209 (6%)
Query: 147 DAGDYVCQISDRVAR-DQVHTVEVLVPPSVRAS-PETRHVTARRGGAAVLECRAAGNPVP 204
DA Y C S+ + + ++V + P++ S + RG + LEC G P P
Sbjct: 2264 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2323
Query: 205 TVTW----HRLNDSS--SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
TVTW H L + L EG LQL + G Y C N G ++ L V
Sbjct: 2324 TVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG-MTDKKYDLSVH 2382
Query: 259 YPPEITVER---SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
PP I + E L C P +W+++ +P+S S V + + G
Sbjct: 2383 APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSTTWFKDGWPVSLSNSVRILSGG-- 2440
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARR 344
L + ED G Y+CV N+ G R+
Sbjct: 2441 RMLRLMQTTMEDAGQYTCVVRNAAGEERK 2469
Score = 69.7 bits (163), Expect = 2e-11
Identities = 56/201 (27%), Positives = 83/201 (41%), Gaps = 14/201 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
DAG Y C ++ T + V VPP +R++ H T A+L C A G P P
Sbjct: 4143 DAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG--HYTVNENSQAILPCVADGIPTPA 4200
Query: 206 VTWHRLND-SSSRLGEGP-----QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W + N ++ LG+ +L L + G Y C +N G T L V
Sbjct: 4201 INWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHT-VSLTVHV 4259
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
P T V +G + L C P +++W N+ + A + + L+
Sbjct: 4260 LPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAH----FDSVNGHSELV 4315
Query: 320 IADVQPEDFGNYSCVADNSLG 340
I V ED G Y C A+NS+G
Sbjct: 4316 IERVSKEDSGTYVCTAENSVG 4336
Score = 69.3 bits (162), Expect = 3e-11
Identities = 54/223 (24%), Positives = 90/223 (40%), Gaps = 14/223 (6%)
Query: 147 DAGDYVC---QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D +Y C I+ + R+ + TV V PP+++ P++ + + + VLEC A G P
Sbjct: 3687 DTANYTCVASNIAGKTTREFILTVNV--PPNIKGGPQSLVILLNK--STVLECIAEGVPT 3742
Query: 204 PTVTWHR----LNDSSSRLG--EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P +TW + L + +R E L + G Y C N G LQV
Sbjct: 3743 PRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDR-RRIDLQV 3801
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + + + L C P ++W +N L+ + S+ +
Sbjct: 3802 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS 3861
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
L+I +D Y C N G +R V+++ + P+ P
Sbjct: 3862 LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEP 3904
Score = 68.5 bits (160), Expect = 5e-11
Identities = 52/213 (24%), Positives = 93/213 (43%), Gaps = 13/213 (6%)
Query: 147 DAGDYVC-QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G+Y+C +++ ++ + ++V VPP ++ + +V+ L C G P P
Sbjct: 1332 DNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVSNVSVLLNQLTNLFCEVEGTPSPI 1391
Query: 206 VTWHRLN----DSSS--RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W++ N +SS+ + G L+L R G Y+C N G F + VL
Sbjct: 1392 IMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTS-QKYFNIDVLV 1450
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNH 316
PP I T V L C V P ++ W+++ PL + V + RG
Sbjct: 1451 PPTIIGTNFPKEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG--Q 1508
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
L + + + D G Y C N+ G+ + ++++
Sbjct: 1509 VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 1541
Score = 68.1 bits (159), Expect = 7e-11
Identities = 55/211 (26%), Positives = 81/211 (38%), Gaps = 15/211 (7%)
Query: 147 DAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D+G+Y C S+ + Q + + + VPPSV + V+ G L C A G P P
Sbjct: 3219 DSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3278
Query: 206 VTWHR-----LNDSSSRL---GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W + + + R+ G L + G Y C N G F L V
Sbjct: 3279 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI-FNLNV 3337
Query: 258 LYPPEITV---ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
P I E + T + C PP +++W +N PL S + + A G
Sbjct: 3338 YVTPTIRGNKDEAEKLMTYVDTSINIECRXTGTPPPQINWLKNGLPLPLSSHIRLLAAG- 3396
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
+ I Q D Y+CVA N G +H
Sbjct: 3397 -QVIRIVRAQVSDVAVYTCVASNRAGVDNKH 3426
Score = 67.7 bits (158), Expect = 9e-11
Identities = 70/277 (25%), Positives = 110/277 (39%), Gaps = 41/277 (14%)
Query: 100 DVTIYENSETSVALAILGATGHTNVW-------ETTRRITSEQHGNTNFRMIFQD--AGD 150
DVT+ NS TS+ T W E+ R I G T + Q+ AG
Sbjct: 2585 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGR 2644
Query: 151 YVCQISDRVARDQVH-TVEVLVPPSVRASP------ETRHVTARRGGAAVLECRAAGNPV 203
Y C ++ H V+V +PP + + V + LEC A P
Sbjct: 2645 YSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPS 2704
Query: 204 PTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+++W++ +D + G LQ+ + G Y C N G + +F + +
Sbjct: 2705 ASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDEL-DFDVNI 2763
Query: 258 LYPPEITVERSW-----VHTGEGFRAE---------LVCTVLADPPAEVSWYQNSFPLSA 303
PP ++ W + TG A+ L C A PP ++WY++ PL++
Sbjct: 2764 QVPPSF--QKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTS 2821
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
S++V + G L I + ED G Y+CVA N G
Sbjct: 2822 SDKVLILPGG--RVLQIPRAKVEDAGRYTCVAVNEAG 2856
Score = 66.9 bits (156), Expect = 2e-10
Identities = 69/260 (26%), Positives = 107/260 (41%), Gaps = 27/260 (10%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHV--TARRGGAA--------VLE 195
D G Y C S+ D++ V + VPPS + E ++ T R G A L
Sbjct: 2740 DTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2799
Query: 196 CRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPV 249
C P PT+TW++ +D L G LQ+ R + G Y C N G
Sbjct: 2800 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDS 2859
Query: 250 VTEFQLQVLYPPEITVERS----WVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE 305
+ ++ ++VL PP I S V A + C P SW ++ PL +
Sbjct: 2860 L-QYDVRVLVPPIIEGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD 2918
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF--TSPPLA 363
+ G L I + Q D G Y CVA+N+ G A+++ ++ P+ S L
Sbjct: 2919 HHKFLSNG--RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLT 2976
Query: 364 RAPHSY-TLSFAVDSYPPLD 382
+++ +L+ V +PP D
Sbjct: 2977 VVVNNFISLTCEVSGFPPPD 2996
Score = 65.7 bits (153), Expect = 4e-10
Identities = 62/235 (26%), Positives = 99/235 (42%), Gaps = 21/235 (8%)
Query: 131 ITSEQHGNTNF-RMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRG 189
IT G+ + R+ QD G+Y C ++ VA T V+V + ++ G
Sbjct: 937 ITVRSDGSLHIERVQLQDGGEYTC-VASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEG 995
Query: 190 GAAVLECRAAGNPVPTVTWHR----LNDSSSRLGEGPQ--LQLSRLERHHGGVYACTVDN 243
L C+A+GNP P+V W + ++ SS++ G L + E G Y CT N
Sbjct: 996 IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPEGEESGEYVCTATN 1055
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGE--------GFRAELVCTVLADPPAEVSWY 295
G + QL V P + + + + G L C V + PP ++W
Sbjct: 1056 TAGY-AKRKVQLTVYVRPRVFGDLRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 1114
Query: 296 QNSFPLSA-SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+ + +S S R T GS + I + + D G Y CVA N G + V+++
Sbjct: 1115 KETQLISPFSPRHTFLPSGS---MKITETRTSDSGMYLCVATNIAGNVTQAVKLN 1166
Score = 63.3 bits (147), Expect = 2e-09
Identities = 60/248 (24%), Positives = 95/248 (38%), Gaps = 16/248 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C + Q + V VPP++ E ++V+ A L C++ P PT
Sbjct: 2077 DTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMG--EEQNVSVLISQAVELLCQSDAIPPPT 2134
Query: 206 VTWHR-----LNDSSSRLGEGPQ-LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+TW + L + E L++ + G Y C N G + + +
Sbjct: 2135 LTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKKNYNVNIWV 2194
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + E + + EG L+C PP + W + P+ +
Sbjct: 2195 PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQ 2254
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTSPP---LARAPHSYTLS 372
L I+ + D YSCVA N G A++ +++V RP S P + S +L
Sbjct: 2255 LQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLE 2314
Query: 373 FAVDSYPP 380
V PP
Sbjct: 2315 CEVQGIPP 2322
Score = 58.0 bits (134), Expect = 7e-08
Identities = 61/229 (26%), Positives = 92/229 (40%), Gaps = 14/229 (6%)
Query: 146 QDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C S+ D Q T+ + P + V G V+EC+ +G P P
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVAL--GDITVMECKTSGIPPP 731
Query: 205 TVTWHRLN---DSSSRLGEGPQLQLSRLERHH---GGVYACTVDNGVGPPVVTEFQLQVL 258
V W + + S+ L P L L +++ G Y C N G + L V
Sbjct: 732 QVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGR-ATGKITLDVG 790
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ-NSFPL-SASERVTMSARGSNH 316
PP E + V G L C V P + W + ++ P+ S V+ ++
Sbjct: 791 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 850
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRH--VEVSGRPGPARFTSPPLA 363
L I ++ D G Y C A+N G+ + V V+G P SP +A
Sbjct: 851 ALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVA 899
Score = 48.8 bits (111), Expect = 4e-05
Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 126 ETTRRITSEQHGNTN-FRMIFQDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRH 183
E + RI +G+ + + +DAGDY C ++ ++ ++ + PP + P
Sbjct: 4392 EISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETV 4451
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLNDSSS 216
+ A GG +L C+A G P PT+TW R S S
Sbjct: 4452 INA--GGKIILNCQATGEPQPTITWSRQGHSIS 4482
>BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein.
Length = 783
Score = 95.9 bits (228), Expect = 3e-19
Identities = 69/194 (35%), Positives = 92/194 (47%), Gaps = 15/194 (7%)
Query: 192 AVLECRAAGNPVPTVTWHR------LNDSSSRLGEGPQL-QLSRLERHHGGVYACTVDNG 244
A C P P ++W R L D+ + E QL + +E G+Y CT +NG
Sbjct: 45 ATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNG 104
Query: 245 VGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
VG V + LQV P+IT V EG +A L CT + +P VSW + PL +
Sbjct: 105 VGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLREN 164
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV---EVSGRPGPARFTS-- 359
R+ + GS L I +VQ ED G Y CVA NSLG A V EV P + T
Sbjct: 165 SRIAVLESGS---LRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEEESEPEQDTKVF 221
Query: 360 PPLARAPHSYTLSF 373
+ RAP S+ ++F
Sbjct: 222 ARILRAPESHNVTF 235
Score = 49.6 bits (113), Expect = 3e-05
Identities = 53/212 (25%), Positives = 91/212 (42%), Gaps = 23/212 (10%)
Query: 147 DAGDYVCQISDRV--ARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C ++ V A + ++V + P + P +V G AVL C GNP P
Sbjct: 93 DDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPI--NVKIIEGLKAVLPCTTMGNPKP 150
Query: 205 TVTWHRLND---SSSRLG--EGPQLQLSRLERHHGGVYACTVDNGVGPPV--VTEFQLQV 257
+V+W + + +SR+ E L++ +++ G Y C N +G V + +++
Sbjct: 151 SVSWIKGDSPLRENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEE 210
Query: 258 LYPPE--ITVERSWVHTGE------GFRAELVCTVLADPPAEVSWYQNSFPLSA-SERVT 308
PE V + E G L CT P ++W +N +S+ S + +
Sbjct: 211 ESEPEQDTKVFARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSIQES 270
Query: 309 MSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
+ R + L + +P G Y+C+A N G
Sbjct: 271 VKDRVIDSRLQLFITKP---GLYTCIATNKHG 299
>AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens cDNA
FLJ31995 fis, clone NT2RP7009236, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 1252
Score = 91.9 bits (218), Expect = 5e-18
Identities = 57/214 (26%), Positives = 95/214 (44%), Gaps = 9/214 (4%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
+ + +DAG Y C ++ Q H + V PPS+ + + + T LEC+AAG
Sbjct: 958 KTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAG 1017
Query: 201 NPVPTVTWHR----LNDSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
NPVP +TW++ L+ S+S L G + + + G+Y C N G + +
Sbjct: 1018 NPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELF-YS 1076
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
LQV P I+ + V L C P ++W ++ P+S+ +
Sbjct: 1077 LQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSG 1135
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
L + Q D G Y+CVA N+ G +R +++
Sbjct: 1136 GRILALTSAQISDTGRYTCVAVNAAGEKQRDIDL 1169
Score = 86.2 bits (204), Expect = 2e-16
Identities = 54/217 (24%), Positives = 96/217 (44%), Gaps = 10/217 (4%)
Query: 147 DAGDYVCQISDRVARDQV-HTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C + ++ + V+VLVPP++ ET + L+C G+P PT
Sbjct: 777 DRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPT 836
Query: 206 VTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W + D L G +L +++ + + G+Y C N G EF++ V
Sbjct: 837 IMWLKDGQLVDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH-KEEFEVTVHV 895
Query: 260 PPEITVERSWVHTGEGFR-AELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP I ++ L C P ++W ++ P++ ++ + + S L
Sbjct: 896 PPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKIQSSGRVL 954
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
IA ED G Y+CVA N+ G ++H+++ P+
Sbjct: 955 QIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPS 991
Score = 76.6 bits (180), Expect = 2e-13
Identities = 79/315 (25%), Positives = 125/315 (39%), Gaps = 31/315 (9%)
Query: 84 YNLQITDVGPQIR---YTVDVTIYENSETSVALAILGATGHTNVW-----ETTRRITSEQ 135
YNL++ V P I+ +V++ N T++ + G +W + T T +
Sbjct: 422 YNLKV-HVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQT 480
Query: 136 HGNTNFRMIF----QDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGG 190
N +F +DAG Y C+ + Q + ++VLVPP++ + V+
Sbjct: 481 VNNGRILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNR 540
Query: 191 AAVLECRAAGNPVPTVTWHR------LNDSS-SRLGEGPQLQLSRLERHHGGVYACTVDN 243
LEC+ G P P + W + L D + L G L L R+ G Y CTV N
Sbjct: 541 DVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSN 600
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRA--ELVCTVLADPPAEVSWYQNSFPL 301
G + +L + PP I + +L C P ++WY++ P+
Sbjct: 601 AAGKQ-AKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPI 659
Query: 302 SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTS 359
+S + +G L I Q D Y+C N G A + HV+V P +
Sbjct: 660 MSSSQALYIDKG--QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLA 717
Query: 360 PPLAR---APHSYTL 371
PL + HS TL
Sbjct: 718 TPLNKQVVIAHSLTL 732
Score = 76.6 bits (180), Expect = 2e-13
Identities = 61/202 (30%), Positives = 85/202 (42%), Gaps = 13/202 (6%)
Query: 147 DAGDYVC-QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
DAG Y C I+ A + ++++V V PS+ S V LEC A G P P+
Sbjct: 1056 DAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNN--PVRLECEARGIPAPS 1113
Query: 206 VTWHRLNDSSSRLGEGPQ-------LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TW + S G Q L L+ + G Y C N G + L+V
Sbjct: 1114 LTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQ-RDIDLRVY 1172
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP I E V EL+C A PP ++W ++ PL +++S S L
Sbjct: 1173 VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRS--VL 1230
Query: 319 LIADVQPEDFGNYSCVADNSLG 340
I D Q +D G Y+C A N G
Sbjct: 1231 KIEDAQVQDTGRYTCEATNVAG 1252
Score = 73.7 bits (173), Expect = 1e-12
Identities = 56/219 (25%), Positives = 89/219 (40%), Gaps = 13/219 (5%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C +S+ + + + +PPS++ T ++ LEC G P+P
Sbjct: 590 DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPA 649
Query: 206 VTWHRLND---SSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+TW++ SSS+ + +G L + R + Y C V N G F + V
Sbjct: 650 ITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAG-TAEKSFHVDVYV 708
Query: 260 PPEITVERSWVHTGEGFRAE---LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP I + + A L C +P ++W ++ P+ A++ + + A G
Sbjct: 709 PPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKK- 767
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L I Q D G Y CVA + G EV PA
Sbjct: 768 -LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPA 805
Score = 72.9 bits (171), Expect = 2e-12
Identities = 60/211 (28%), Positives = 88/211 (41%), Gaps = 18/211 (8%)
Query: 147 DAGDYVCQISDRVARDQVHTVE--VLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D+G Y+C ++ +A + V+ V VPP ++ P +H+ + G + C A G P+P
Sbjct: 215 DSGMYLC-VAINIAGNVTQAVKLNVHVPPKIQRGP--KHLKVQVGQRVDIPCNAQGTPLP 271
Query: 205 TVTWHRLNDSSSRLGE----GPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TW + + GE P L + + G+Y C N G TE L V
Sbjct: 272 VITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDE-TEITLHVQ 330
Query: 259 YPPEIT-VERSWVHTGE----GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
PP + +E + T + R E C P + W N L+ E +S
Sbjct: 331 EPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREP-GISILE 389
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
L+IA V P D G Y CVA N G R
Sbjct: 390 DGTLLVIASVTPYDNGEYICVAVNEAGTTER 420
Score = 68.5 bits (160), Expect = 5e-11
Identities = 52/213 (24%), Positives = 94/213 (44%), Gaps = 13/213 (6%)
Query: 147 DAGDYVC-QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G+Y+C +++ ++ + ++V VPP ++ + +V+ L C G P P
Sbjct: 403 DNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPI 462
Query: 206 VTWHRLN----DSSS--RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W++ N +SS+ + G L+L R G Y+C N G F + VL
Sbjct: 463 IMWYKDNVQVTESSTIQTVNNGRILKLFRATPEDAGRYSCKAINIAGTS-QKYFNIDVLV 521
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNH 316
PP I T + V L C V P ++ W+++ PL + V + RG
Sbjct: 522 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG--Q 579
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
L + + + D G Y C N+ G+ + ++++
Sbjct: 580 VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLT 612
Score = 63.3 bits (147), Expect = 2e-09
Identities = 61/235 (25%), Positives = 99/235 (42%), Gaps = 21/235 (8%)
Query: 131 ITSEQHGNTNF-RMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRG 189
IT G+ + R+ QD G+Y C ++ VA T V+V + ++ G
Sbjct: 8 ITVRSDGSLHIERVQLQDGGEYTC-VASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEG 66
Query: 190 GAAVLECRAAGNPVPTVTWHR----LNDSSSRLGEGP--QLQLSRLERHHGGVYACTVDN 243
L C+A+GNP P+V W + ++ SS++ G L + G Y CT N
Sbjct: 67 IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 126
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGE--------GFRAELVCTVLADPPAEVSWY 295
G + QL V P + ++ + + G L C V + PP ++W
Sbjct: 127 TAG-YAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 185
Query: 296 QNSFPLSA-SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+ + +S S R T GS + I + + D G Y CVA N G + V+++
Sbjct: 186 KETQLISPFSPRHTFLPSGS---MKITETRTSDSGMYLCVAINIAGNVTQAVKLN 237
>BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein.
Length = 773
Score = 91.5 bits (217), Expect = 6e-18
Identities = 67/189 (35%), Positives = 89/189 (47%), Gaps = 15/189 (7%)
Query: 192 AVLECRAAGNPVPTVTWHR------LNDSSSRLGEGPQL-QLSRLERHHGGVYACTVDNG 244
A C P P ++W R L D+ + E QL + +E G+Y CT +NG
Sbjct: 45 ATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNG 104
Query: 245 VGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
VG V + LQV P+IT V EG +A L CT + +P VSW + PL +
Sbjct: 105 VGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLREN 164
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR 364
R+ + GS L I +VQ ED G Y CVA NSLG A V AR + R
Sbjct: 165 SRIAVLESGS---LRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFAR-----ILR 216
Query: 365 APHSYTLSF 373
AP S+ ++F
Sbjct: 217 APESHNVTF 225
Score = 56.8 bits (131), Expect = 2e-07
Identities = 51/202 (25%), Positives = 87/202 (43%), Gaps = 13/202 (6%)
Query: 147 DAGDYVCQISDRV--ARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C ++ V A + ++V + P + P +V G AVL C GNP P
Sbjct: 93 DDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPI--NVKIIEGLKAVLPCTTMGNPKP 150
Query: 205 TVTWHRLND---SSSRLG--EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+V+W + + +SR+ E L++ +++ G Y C N +G +L+V
Sbjct: 151 SVSWIKGDSPLRENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEV 210
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA-SERVTMSARGSNHTL 318
I + G L CT P ++W +N +S+ S + ++ R + L
Sbjct: 211 FARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRL 270
Query: 319 LIADVQPEDFGNYSCVADNSLG 340
+ +P G Y+C+A N G
Sbjct: 271 QLFITKP---GLYTCIATNKHG 289
Score = 44.4 bits (100), Expect = 0.001
Identities = 36/109 (33%), Positives = 53/109 (48%), Gaps = 10/109 (9%)
Query: 146 QDAGDYVCQISDRV--ARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
+DAG Y C + + A +V +EV V + +PE+ +VT G L C A G PV
Sbjct: 183 EDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHNVTF--GSFVTLHCTATGIPV 240
Query: 204 PTVTWHRLND--SSSRLGEGPQLQL--SRLERH--HGGVYACTVDNGVG 246
PT+TW + SS + E + ++ SRL+ G+Y C N G
Sbjct: 241 PTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHG 289
>AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 91.5 bits (217), Expect = 6e-18
Identities = 67/189 (35%), Positives = 89/189 (47%), Gaps = 15/189 (7%)
Query: 192 AVLECRAAGNPVPTVTWHR------LNDSSSRLGEGPQL-QLSRLERHHGGVYACTVDNG 244
A C P P ++W R L D+ + E QL + +E G+Y CT +NG
Sbjct: 45 ATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNG 104
Query: 245 VGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
VG V + LQV P+IT V EG +A L CT + +P VSW + PL +
Sbjct: 105 VGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLREN 164
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR 364
R+ + GS L I +VQ ED G Y CVA NSLG A V AR + R
Sbjct: 165 SRIAVLESGS---LRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFAR-----ILR 216
Query: 365 APHSYTLSF 373
AP S+ ++F
Sbjct: 217 APESHNVTF 225
Score = 56.8 bits (131), Expect = 2e-07
Identities = 51/202 (25%), Positives = 87/202 (43%), Gaps = 13/202 (6%)
Query: 147 DAGDYVCQISDRV--ARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C ++ V A + ++V + P + P +V G AVL C GNP P
Sbjct: 93 DDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPI--NVKIIEGLKAVLPCTTMGNPKP 150
Query: 205 TVTWHRLND---SSSRLG--EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+V+W + + +SR+ E L++ +++ G Y C N +G +L+V
Sbjct: 151 SVSWIKGDSPLRENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEV 210
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA-SERVTMSARGSNHTL 318
I + G L CT P ++W +N +S+ S + ++ R + L
Sbjct: 211 FARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRL 270
Query: 319 LIADVQPEDFGNYSCVADNSLG 340
+ +P G Y+C+A N G
Sbjct: 271 QLFITKP---GLYTCIATNKHG 289
Score = 44.4 bits (100), Expect = 0.001
Identities = 36/109 (33%), Positives = 53/109 (48%), Gaps = 10/109 (9%)
Query: 146 QDAGDYVCQISDRV--ARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
+DAG Y C + + A +V +EV V + +PE+ +VT G L C A G PV
Sbjct: 183 EDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHNVTF--GSFVTLHCTATGIPV 240
Query: 204 PTVTWHRLND--SSSRLGEGPQLQL--SRLERH--HGGVYACTVDNGVG 246
PT+TW + SS + E + ++ SRL+ G+Y C N G
Sbjct: 241 PTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHG 289
>AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 91.5 bits (217), Expect = 6e-18
Identities = 67/189 (35%), Positives = 89/189 (47%), Gaps = 15/189 (7%)
Query: 192 AVLECRAAGNPVPTVTWHR------LNDSSSRLGEGPQL-QLSRLERHHGGVYACTVDNG 244
A C P P ++W R L D+ + E QL + +E G+Y CT +NG
Sbjct: 45 ATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNG 104
Query: 245 VGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
VG V + LQV P+IT V EG +A L CT + +P VSW + PL +
Sbjct: 105 VGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLREN 164
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR 364
R+ + GS L I +VQ ED G Y CVA NSLG A V AR + R
Sbjct: 165 SRIAVLESGS---LRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFAR-----ILR 216
Query: 365 APHSYTLSF 373
AP S+ ++F
Sbjct: 217 APESHNVTF 225
Score = 56.8 bits (131), Expect = 2e-07
Identities = 51/202 (25%), Positives = 87/202 (43%), Gaps = 13/202 (6%)
Query: 147 DAGDYVCQISDRV--ARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C ++ V A + ++V + P + P +V G AVL C GNP P
Sbjct: 93 DDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPI--NVKIIEGLKAVLPCTTMGNPKP 150
Query: 205 TVTWHRLND---SSSRLG--EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+V+W + + +SR+ E L++ +++ G Y C N +G +L+V
Sbjct: 151 SVSWIKGDSPLRENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEV 210
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA-SERVTMSARGSNHTL 318
I + G L CT P ++W +N +S+ S + ++ R + L
Sbjct: 211 FARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRL 270
Query: 319 LIADVQPEDFGNYSCVADNSLG 340
+ +P G Y+C+A N G
Sbjct: 271 QLFITKP---GLYTCIATNKHG 289
Score = 44.4 bits (100), Expect = 0.001
Identities = 36/109 (33%), Positives = 53/109 (48%), Gaps = 10/109 (9%)
Query: 146 QDAGDYVCQISDRV--ARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
+DAG Y C + + A +V +EV V + +PE+ +VT G L C A G PV
Sbjct: 183 EDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHNVTF--GSFVTLHCTATGIPV 240
Query: 204 PTVTWHRLND--SSSRLGEGPQLQL--SRLERH--HGGVYACTVDNGVG 246
PT+TW + SS + E + ++ SRL+ G+Y C N G
Sbjct: 241 PTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHG 289
>AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 91.5 bits (217), Expect = 6e-18
Identities = 67/189 (35%), Positives = 89/189 (47%), Gaps = 15/189 (7%)
Query: 192 AVLECRAAGNPVPTVTWHR------LNDSSSRLGEGPQL-QLSRLERHHGGVYACTVDNG 244
A C P P ++W R L D+ + E QL + +E G+Y CT +NG
Sbjct: 45 ATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNG 104
Query: 245 VGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
VG V + LQV P+IT V EG +A L CT + +P VSW + PL +
Sbjct: 105 VGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLREN 164
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR 364
R+ + GS L I +VQ ED G Y CVA NSLG A V AR + R
Sbjct: 165 SRIAVLESGS---LRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFAR-----ILR 216
Query: 365 APHSYTLSF 373
AP S+ ++F
Sbjct: 217 APESHNVTF 225
Score = 56.8 bits (131), Expect = 2e-07
Identities = 51/202 (25%), Positives = 87/202 (43%), Gaps = 13/202 (6%)
Query: 147 DAGDYVCQISDRV--ARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C ++ V A + ++V + P + P +V G AVL C GNP P
Sbjct: 93 DDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPI--NVKIIEGLKAVLPCTTMGNPKP 150
Query: 205 TVTWHRLND---SSSRLG--EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+V+W + + +SR+ E L++ +++ G Y C N +G +L+V
Sbjct: 151 SVSWIKGDSPLRENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEV 210
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA-SERVTMSARGSNHTL 318
I + G L CT P ++W +N +S+ S + ++ R + L
Sbjct: 211 FARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRL 270
Query: 319 LIADVQPEDFGNYSCVADNSLG 340
+ +P G Y+C+A N G
Sbjct: 271 QLFITKP---GLYTCIATNKHG 289
Score = 44.4 bits (100), Expect = 0.001
Identities = 36/109 (33%), Positives = 53/109 (48%), Gaps = 10/109 (9%)
Query: 146 QDAGDYVCQISDRV--ARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
+DAG Y C + + A +V +EV V + +PE+ +VT G L C A G PV
Sbjct: 183 EDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHNVTF--GSFVTLHCTATGIPV 240
Query: 204 PTVTWHRLND--SSSRLGEGPQLQL--SRLERH--HGGVYACTVDNGVG 246
PT+TW + SS + E + ++ SRL+ G+Y C N G
Sbjct: 241 PTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHG 289
>AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 91.5 bits (217), Expect = 6e-18
Identities = 67/189 (35%), Positives = 89/189 (47%), Gaps = 15/189 (7%)
Query: 192 AVLECRAAGNPVPTVTWHR------LNDSSSRLGEGPQL-QLSRLERHHGGVYACTVDNG 244
A C P P ++W R L D+ + E QL + +E G+Y CT +NG
Sbjct: 45 ATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNG 104
Query: 245 VGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
VG V + LQV P+IT V EG +A L CT + +P VSW + PL +
Sbjct: 105 VGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLREN 164
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR 364
R+ + GS L I +VQ ED G Y CVA NSLG A V AR + R
Sbjct: 165 SRIAVLESGS---LRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFAR-----ILR 216
Query: 365 APHSYTLSF 373
AP S+ ++F
Sbjct: 217 APESHNVTF 225
Score = 56.8 bits (131), Expect = 2e-07
Identities = 51/202 (25%), Positives = 87/202 (43%), Gaps = 13/202 (6%)
Query: 147 DAGDYVCQISDRV--ARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C ++ V A + ++V + P + P +V G AVL C GNP P
Sbjct: 93 DDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPI--NVKIIEGLKAVLPCTTMGNPKP 150
Query: 205 TVTWHRLND---SSSRLG--EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+V+W + + +SR+ E L++ +++ G Y C N +G +L+V
Sbjct: 151 SVSWIKGDSPLRENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEV 210
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA-SERVTMSARGSNHTL 318
I + G L CT P ++W +N +S+ S + ++ R + L
Sbjct: 211 FARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRL 270
Query: 319 LIADVQPEDFGNYSCVADNSLG 340
+ +P G Y+C+A N G
Sbjct: 271 QLFITKP---GLYTCIATNKHG 289
Score = 44.4 bits (100), Expect = 0.001
Identities = 36/109 (33%), Positives = 53/109 (48%), Gaps = 10/109 (9%)
Query: 146 QDAGDYVCQISDRV--ARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
+DAG Y C + + A +V +EV V + +PE+ +VT G L C A G PV
Sbjct: 183 EDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHNVTF--GSFVTLHCTATGIPV 240
Query: 204 PTVTWHRLND--SSSRLGEGPQLQL--SRLERH--HGGVYACTVDNGVG 246
PT+TW + SS + E + ++ SRL+ G+Y C N G
Sbjct: 241 PTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHG 289
>AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosine
kinase receptor protein.
Length = 869
Score = 91.5 bits (217), Expect = 6e-18
Identities = 67/189 (35%), Positives = 89/189 (47%), Gaps = 15/189 (7%)
Query: 192 AVLECRAAGNPVPTVTWHR------LNDSSSRLGEGPQL-QLSRLERHHGGVYACTVDNG 244
A C P P ++W R L D+ + E QL + +E G+Y CT +NG
Sbjct: 45 ATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNG 104
Query: 245 VGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
VG V + LQV P+IT V EG +A L CT + +P VSW + PL +
Sbjct: 105 VGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLREN 164
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR 364
R+ + GS L I +VQ ED G Y CVA NSLG A V AR + R
Sbjct: 165 SRIAVLESGS---LRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFAR-----ILR 216
Query: 365 APHSYTLSF 373
AP S+ ++F
Sbjct: 217 APESHNVTF 225
Score = 57.2 bits (132), Expect = 1e-07
Identities = 53/222 (23%), Positives = 93/222 (41%), Gaps = 13/222 (5%)
Query: 147 DAGDYVCQISDRV--ARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C ++ V A + ++V + P + P +V G AVL C GNP P
Sbjct: 93 DDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPI--NVKIIEGLKAVLPCTTMGNPKP 150
Query: 205 TVTWHRLND---SSSRLG--EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+V+W + + +SR+ E L++ +++ G Y C N +G +L+V
Sbjct: 151 SVSWIKGDSPLRENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEV 210
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA-SERVTMSARGSNHTL 318
I + G L CT P ++W +N +S+ S + ++ R + L
Sbjct: 211 FARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRL 270
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
+ +P G Y+C+A N G + + A ++ P
Sbjct: 271 QLFITKP---GLYTCIATNKHGEKFSTAKAAATISIAEWSKP 309
Score = 44.4 bits (100), Expect = 0.001
Identities = 36/109 (33%), Positives = 53/109 (48%), Gaps = 10/109 (9%)
Query: 146 QDAGDYVCQISDRV--ARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
+DAG Y C + + A +V +EV V + +PE+ +VT G L C A G PV
Sbjct: 183 EDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHNVTF--GSFVTLHCTATGIPV 240
Query: 204 PTVTWHRLND--SSSRLGEGPQLQL--SRLERH--HGGVYACTVDNGVG 246
PT+TW + SS + E + ++ SRL+ G+Y C N G
Sbjct: 241 PTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHG 289
>AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein
protein.
Length = 1340
Score = 90.6 bits (215), Expect = 1e-17
Identities = 71/211 (33%), Positives = 98/211 (46%), Gaps = 16/211 (7%)
Query: 147 DAGDYVCQISDRVARDQVHT--VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C++S+ VA + V T + V VPP+ +P+T V+ G VL C +G P P
Sbjct: 10 DKGLYSCKVSN-VAGEAVRTFTLTVQVPPTFE-NPKTETVSQVAGSPLVLTCDVSGVPAP 67
Query: 205 TVTW--HRLNDSSSR----LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
TVTW R+ SS + G +LQLSRL+ G Y C +N +F + VL
Sbjct: 68 TVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN-TQAEARKDFVVAVL 126
Query: 259 YPPEIT---VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
P I V R H EG L C PP +V+W ++ PL +
Sbjct: 127 VAPRIRSSGVAREH-HVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDG 185
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGR-ARRH 345
+L++ + D G Y+CVA N G AR H
Sbjct: 186 GSLVLKGLWASDAGAYTCVAHNPAGEDARLH 216
Score = 90.6 bits (215), Expect = 1e-17
Identities = 62/209 (29%), Positives = 99/209 (47%), Gaps = 13/209 (6%)
Query: 148 AGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
AG Y C + H + V P V+ P A +L C A+G P PT+
Sbjct: 819 AGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEE--EVLLPCEASGIPRPTI 876
Query: 207 TWHR--LNDS---SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP 261
TW + LN + S+++ G QL+++ G Y C N G + + +L V PP
Sbjct: 877 TWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGS-AMGKTRLVVQVPP 935
Query: 262 EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNHTLLI 320
I + T EG A L C P ++W ++ P+S +E + T+ G LL+
Sbjct: 936 VIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGE---LLV 992
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+++ +D G Y+C A+N++GRARR V ++
Sbjct: 993 KNLEGQDAGTYTCTAENAVGRARRRVHLT 1021
Score = 87.0 bits (206), Expect = 1e-16
Identities = 63/208 (30%), Positives = 94/208 (45%), Gaps = 14/208 (6%)
Query: 146 QDAGDYVCQISDRV--ARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
QDAG Y C + V AR +VH + +LV P P R + R G L C A G+P
Sbjct: 998 QDAGTYTCTAENAVGRARRRVH-LTILVLPVFTTLPGDRSL--RLGDRLWLRCAARGSPT 1054
Query: 204 PTVTW----HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
P + W + + S G LQ + + R G Y C +N VG F + V
Sbjct: 1055 PRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSF-VHVKE 1113
Query: 260 PPEITVER-SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
P + E S++ G +L C V DP ++ W ++ PL S + + N +L
Sbjct: 1114 APVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSH---LRHQLQNGSL 1170
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHV 346
I + +D G Y C+A+N +G A++ V
Sbjct: 1171 TIHRTERDDAGRYQCLAENEMGVAKKVV 1198
Score = 86.2 bits (204), Expect = 2e-16
Identities = 72/213 (33%), Positives = 90/213 (42%), Gaps = 21/213 (9%)
Query: 148 AGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
AG Y C + A + V VLV P +R+S R G L+C A G P P V
Sbjct: 103 AGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDV 162
Query: 207 TWHRLNDSSSRLGE--GPQLQ---------LSRLERHHGGVYACTVDNGVGPPVVTEFQL 255
W L D S LG+ GP L+ L L G Y C N G +
Sbjct: 163 AW--LKDGSP-LGQDMGPHLRFYLDGGSLVLKGLWASDAGAYTCVAHNPAGEDARLH-TV 218
Query: 256 QVLYPPEITVERSWVHT---GEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
VL PP I T G +VC V PP VSW ++ PL S+R +
Sbjct: 219 NVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLL--H 276
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
GS HTL I+ VQ D G ++CVA + G A R+
Sbjct: 277 GSGHTLRISKVQLADAGIFTCVAASPAGVADRN 309
Score = 83.4 bits (197), Expect = 2e-15
Identities = 67/207 (32%), Positives = 89/207 (42%), Gaps = 12/207 (5%)
Query: 146 QDAGDYVCQI-SDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C S A ++ V V PP++ R V G VLEC P P
Sbjct: 468 RDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAP 527
Query: 205 TVTWHR-----LNDSSSRLGE-GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TWHR D+ ++ E G LQL L G Y+CT N G V F++++
Sbjct: 528 KITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVA-FRVEIH 586
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLS-ASERVTMSARGSNHT 317
P I V+ A L C P VSW ++ PL S R + GS
Sbjct: 587 TVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGS--- 643
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARR 344
L I V +D G+Y C+A NS G R+
Sbjct: 644 LRIQPVLAQDAGHYLCLASNSAGSDRQ 670
Score = 83.0 bits (196), Expect = 2e-15
Identities = 69/220 (31%), Positives = 97/220 (44%), Gaps = 16/220 (7%)
Query: 133 SEQHGNTNFRMIF---QDAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARR 188
SEQ G + + +D+G YVC +RV R Q V V V P ++ + ++
Sbjct: 1071 SEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFS-YLVEPV 1129
Query: 189 GGAAVLECRAAGNPVPTVTWHR----LNDSSSRLG-EGPQLQLSRLERHHGGVYACTVDN 243
GG+ L+C G+PVP + W + L S R + L + R ER G Y C +N
Sbjct: 1130 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAEN 1189
Query: 244 GVGPPVVTEFQLQVLYP-PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLS 302
+G V + + VL P VE + G L C +P + W Q PL
Sbjct: 1190 EMG--VAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLR 1247
Query: 303 ASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
AS R+ GS L + +V+ D G Y CVA N LG A
Sbjct: 1248 ASRRLRTLPDGS---LWLENVETGDAGTYDCVAHNLLGSA 1284
Score = 79.8 bits (188), Expect = 2e-14
Identities = 55/222 (24%), Positives = 94/222 (42%), Gaps = 10/222 (4%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D+G Y C + H + V+ PP + S + ++ G L C A G P P
Sbjct: 378 DSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPN 437
Query: 206 VTWHRLNDSSSRLGEGPQ----LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP 261
+TWH+ + +RL + L++ ++ G+Y C ++ G + F+++V PP
Sbjct: 438 ITWHKDGQALTRLENNSRATRVLRVENVQVRDAGLYTCLAESPAG-AIEKSFRVRVQAPP 496
Query: 262 EITVERS--WVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
I R +V + L C+V A+P +++W+++ L RG L
Sbjct: 497 NIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERG--RFLQ 554
Query: 320 IADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPP 361
+ + D G+YSC A N+ G V P + PP
Sbjct: 555 LQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPP 596
Score = 61.3 bits (142), Expect = 8e-09
Identities = 49/165 (29%), Positives = 72/165 (43%), Gaps = 10/165 (6%)
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERS-WVHTGEGFRAELVC 282
L++ + G+Y+C V N G V T F L V PP ++ V G L C
Sbjct: 1 LEIQEAQVSDKGLYSCKVSNVAGEAVRT-FTLTVQVPPTFENPKTETVSQVAGSPLVLTC 59
Query: 283 TVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
V P V+W ++ P+ +S + +RG L ++ +QP G Y+CVA+N+ A
Sbjct: 60 DVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGR--LQLSRLQPAQAGTYTCVAENTQAEA 117
Query: 343 RRHVEVSGRPGPARFTSPPLARAPH-----SYTLSFAVDSYPPLD 382
R+ V+ P R S +AR H L D PP D
Sbjct: 118 RKDFVVAVLVAP-RIRSSGVAREHHVLEGQEVRLDCEADGQPPPD 161
Score = 58.4 bits (135), Expect = 5e-08
Identities = 52/200 (26%), Positives = 83/200 (41%), Gaps = 19/200 (9%)
Query: 186 ARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGV 245
AR G L CR + P + S L +GP LQL + G Y+C +
Sbjct: 339 ARPGAFPCLSCRGMKDGEPLL--------SQSLEQGPSLQLEAVGAGDSGTYSCVAVSEA 390
Query: 246 GPPVVTEFQLQVLYPPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA 303
G FQL V+ PP I + + + + G EL+C P ++W+++ L+
Sbjct: 391 G-EARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTR 449
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTSP- 360
E + + R L + +VQ D G Y+C+A++ G + V V P P
Sbjct: 450 LENNSRATR----VLRVENVQVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPR 505
Query: 361 -PLARAPHSYTLSFAVDSYP 379
+ AP L +V++ P
Sbjct: 506 FVVGLAPGQLVLECSVEAEP 525
Score = 55.2 bits (127), Expect = 5e-07
Identities = 52/183 (28%), Positives = 72/183 (39%), Gaps = 13/183 (7%)
Query: 192 AVLECRAAGNPVPTVTW--------HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDN 243
A+L C A+G+P P V W RL + RL L L+ + C V N
Sbjct: 678 ALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSN 737
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA 303
VG +Q+ V PP I +++ L C P VSW + L A
Sbjct: 738 EVGE-AHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGA 796
Query: 304 -SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPL 362
+S G+ L I P G Y+C A NS G A +HV ++ + P P +
Sbjct: 797 RGSGYRVSPSGA---LEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSV 853
Query: 363 ARA 365
RA
Sbjct: 854 VRA 856
Score = 46.0 bits (104), Expect = 3e-04
Identities = 37/125 (29%), Positives = 51/125 (40%), Gaps = 7/125 (5%)
Query: 135 QHGN-TNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAV 193
Q+G+ T R DAG Y C + + + + VL V E + +T R G
Sbjct: 1166 QNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPV-FQVEPQDMTVRSGDDVA 1224
Query: 194 LECRAAGNPVPTVTWHRLND---SSSRLGEGP--QLQLSRLERHHGGVYACTVDNGVGPP 248
L C+A G P PT+ W + +S RL P L L +E G Y C N +G
Sbjct: 1225 LRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSA 1284
Query: 249 VVTEF 253
F
Sbjct: 1285 TARAF 1289
>AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens
cDNA FLJ36264 fis, clone THYMU2002815, weakly similar to
AXONIN-1 PRECURSOR. ).
Length = 329
Score = 90.6 bits (215), Expect = 1e-17
Identities = 62/209 (29%), Positives = 99/209 (47%), Gaps = 13/209 (6%)
Query: 148 AGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
AG Y C + H + V P V+ P A +L C A+G P PT+
Sbjct: 53 AGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEE--EVLLPCEASGIPRPTI 110
Query: 207 TWHR--LNDS---SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP 261
TW + LN + S+++ G QL+++ G Y C N G + + +L V PP
Sbjct: 111 TWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGS-AMGKTRLVVQVPP 169
Query: 262 EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNHTLLI 320
I + T EG A L C P ++W ++ P+S +E + T+ G LL+
Sbjct: 170 VIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGE---LLV 226
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+++ +D G Y+C A+N++GRARR V ++
Sbjct: 227 KNLEGQDAGTYTCTAENAVGRARRRVHLT 255
Score = 58.0 bits (134), Expect = 7e-08
Identities = 44/156 (28%), Positives = 60/156 (38%), Gaps = 10/156 (6%)
Query: 193 VLECRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVG 246
VL C + G P PTV+W + S R+ L++ + H G Y C+ N G
Sbjct: 6 VLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAG 65
Query: 247 PPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASER 306
F L V P + S V L C P ++W + ++
Sbjct: 66 VAHKHVF-LTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVS 124
Query: 307 VTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+ G L IA PED GNY C+A NS G A
Sbjct: 125 TQVLPGGQ---LRIAHASPEDAGNYLCIAKNSAGSA 157
Score = 40.3 bits (90), Expect = 0.015
Identities = 27/70 (38%), Positives = 35/70 (50%), Gaps = 6/70 (8%)
Query: 146 QDAGDYVCQISDRV--ARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
QDAG Y C + V AR +VH + +LV P P R + R G L C A G+P
Sbjct: 232 QDAGTYTCTAENAVGRARRRVH-LTILVLPVFTTLPGDRSL--RLGDRLWLRCAARGSPT 288
Query: 204 PTVTWHRLND 213
P + W +ND
Sbjct: 289 PRIGW-TVND 297
Score = 35.1 bits (77), Expect = 0.58
Identities = 27/87 (31%), Positives = 36/87 (41%), Gaps = 4/87 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSA-SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNS 338
L C P VSW + L A +S G+ L I P G Y+C A NS
Sbjct: 7 LTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGA---LEIGQALPIHAGRYTCSARNS 63
Query: 339 LGRARRHVEVSGRPGPARFTSPPLARA 365
G A +HV ++ + P P + RA
Sbjct: 64 AGVAHKHVFLTVQASPVVKPLPSVVRA 90
>BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell
adhesion molecule protein.
Length = 814
Score = 89.4 bits (212), Expect = 3e-17
Identities = 62/196 (31%), Positives = 88/196 (44%), Gaps = 17/196 (8%)
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN------DSSSRLGEGPQLQL 226
P++ PE +T + AVLEC A GNP P V+W RL+ + LG G L +
Sbjct: 238 PAILVGPENLTLTVHQ--TAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTG-NLII 294
Query: 227 SRLERHHGGVYACTVDN-GVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVL 285
S + H GVY C + G + +L V P E + G A C
Sbjct: 295 SDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQ 354
Query: 286 ADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
+PP V+W +N L V + + +N TL I+ + PED Y CVA+NS G ++
Sbjct: 355 GEPPPHVTWLKNGQVLGPGGHVRL--KNNNSTLTISGIGPEDEAIYQCVAENSAGSSQAS 412
Query: 346 VEVS-----GRPGPAR 356
++ G PGP R
Sbjct: 413 ARLTVLWAEGLPGPPR 428
Score = 55.2 bits (127), Expect = 5e-07
Identities = 53/199 (26%), Positives = 79/199 (39%), Gaps = 19/199 (9%)
Query: 189 GGAAVLECRAAGNPVPTVTWHR----LNDSS-SRLGEGPQLQLSRLERHHGGV------Y 237
G VL+CR G P +TW + L +S+ S L L + GG Y
Sbjct: 56 GQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDY 115
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQN 297
C N G V + ++Q + V EG A C + P ++W +N
Sbjct: 116 ECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARFQCQIHGLPKPLITWEKN 175
Query: 298 SFPLSA-SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH---VEVSGRPG 353
P+ +ER T+ +G L I ++ ED G + CVA N H + VSG G
Sbjct: 176 RVPIDTDNERYTLLPKG---VLQITGLRAEDGGIFHCVASNIASIRISHGARLTVSG-SG 231
Query: 354 PARFTSPPLARAPHSYTLS 372
+ P + P + TL+
Sbjct: 232 SGAYKEPAILVGPENLTLT 250
Score = 48.0 bits (109), Expect = 8e-05
Identities = 55/231 (23%), Positives = 83/231 (35%), Gaps = 21/231 (9%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D GDY C +R + + GG A +C+ G P P +
Sbjct: 111 DEGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARFQCQIHGLPKPLI 170
Query: 207 TWHR----LNDSSSRLGEGPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV--- 257
TW + ++ + R P+ LQ++ L GG++ C N + +L V
Sbjct: 171 TWEKNRVPIDTDNERYTLLPKGVLQITGLRAEDGGIFHCVASNIASIRISHGARLTVSGS 230
Query: 258 ----LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
P I V + A L C +P VSW + E + + G
Sbjct: 231 GSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTG 290
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR---PGPARFTSPP 361
+ L+I+DV + G Y C A+ R RR + GR PA F P
Sbjct: 291 N---LIISDVTVQHSGVYVCAANRPGTRVRRTAQ--GRLVVQAPAEFVQHP 336
>BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell
adhesion molecule protein.
Length = 814
Score = 89.4 bits (212), Expect = 3e-17
Identities = 62/196 (31%), Positives = 88/196 (44%), Gaps = 17/196 (8%)
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN------DSSSRLGEGPQLQL 226
P++ PE +T + AVLEC A GNP P V+W RL+ + LG G L +
Sbjct: 238 PAILVGPENLTLTVHQ--TAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTG-NLII 294
Query: 227 SRLERHHGGVYACTVDN-GVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVL 285
S + H GVY C + G + +L V P E + G A C
Sbjct: 295 SDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQ 354
Query: 286 ADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
+PP V+W +N L V + + +N TL I+ + PED Y CVA+NS G ++
Sbjct: 355 GEPPPHVTWLKNGQVLGPGGHVRL--KNNNSTLTISGIGPEDEAIYQCVAENSAGSSQAS 412
Query: 346 VEVS-----GRPGPAR 356
++ G PGP R
Sbjct: 413 ARLTVLWAEGLPGPPR 428
Score = 55.2 bits (127), Expect = 5e-07
Identities = 53/199 (26%), Positives = 79/199 (39%), Gaps = 19/199 (9%)
Query: 189 GGAAVLECRAAGNPVPTVTWHR----LNDSS-SRLGEGPQLQLSRLERHHGGV------Y 237
G VL+CR G P +TW + L +S+ S L L + GG Y
Sbjct: 56 GQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDY 115
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQN 297
C N G V + ++Q + V EG A C + P ++W +N
Sbjct: 116 ECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARFQCQIHGLPKPLITWEKN 175
Query: 298 SFPLSA-SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH---VEVSGRPG 353
P+ +ER T+ +G L I ++ ED G + CVA N H + VSG G
Sbjct: 176 RVPIDTDNERYTLLPKG---VLQITGLRAEDGGIFHCVASNIASIRISHGARLTVSG-SG 231
Query: 354 PARFTSPPLARAPHSYTLS 372
+ P + P + TL+
Sbjct: 232 SGAYKEPAILVGPENLTLT 250
Score = 48.0 bits (109), Expect = 8e-05
Identities = 55/231 (23%), Positives = 83/231 (35%), Gaps = 21/231 (9%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D GDY C +R + + GG A +C+ G P P +
Sbjct: 111 DEGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARFQCQIHGLPKPLI 170
Query: 207 TWHR----LNDSSSRLGEGPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV--- 257
TW + ++ + R P+ LQ++ L GG++ C N + +L V
Sbjct: 171 TWEKNRVPIDTDNERYTLLPKGVLQITGLRAEDGGIFHCVASNIASIRISHGARLTVSGS 230
Query: 258 ----LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
P I V + A L C +P VSW + E + + G
Sbjct: 231 GSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTG 290
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR---PGPARFTSPP 361
+ L+I+DV + G Y C A+ R RR + GR PA F P
Sbjct: 291 N---LIISDVTVQHSGVYVCAANRPGTRVRRTAQ--GRLVVQAPAEFVQHP 336
>AY358132-1|AAQ88499.1| 352|Homo sapiens DMML2433 protein.
Length = 352
Score = 89.4 bits (212), Expect = 3e-17
Identities = 57/197 (28%), Positives = 88/197 (44%), Gaps = 7/197 (3%)
Query: 147 DAGDYVCQI-SDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C + + R QVH + V VPP + + +T G L C A G P P
Sbjct: 110 DDGPYTCSVQTQHTPRTMQVH-LTVQVPPKIYDI--SNDMTVNEGTNVTLTCLATGKPEP 166
Query: 205 TVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEIT 264
+++W ++ S+ G L + + R G Y C+ +N V P V + ++ V + P I
Sbjct: 167 SISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENAVSFPDVRKVKVVVNFAPTIQ 226
Query: 265 VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL-SASERVTMSARGSNHTLLIADV 323
+S T G + C PP WY+ L + + + + + L + +V
Sbjct: 227 EIKSGTVT-PGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNV 285
Query: 324 QPEDFGNYSCVADNSLG 340
E FGNY+CVA N LG
Sbjct: 286 TQEHFGNYTCVAANKLG 302
>BX538014-1|CAD97961.1| 355|Homo sapiens hypothetical protein
protein.
Length = 355
Score = 89.0 bits (211), Expect = 3e-17
Identities = 57/197 (28%), Positives = 88/197 (44%), Gaps = 7/197 (3%)
Query: 147 DAGDYVCQI-SDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C + + R QVH + V VPP + + +T G L C A G P P
Sbjct: 113 DDGPYTCSVQTQHTPRTMQVH-LTVQVPPKIYDI--SNDMTVNEGTNVTLTCLATGKPEP 169
Query: 205 TVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEIT 264
+++W ++ S+ G L + + R G Y C+ +N V P V + ++ V + P I
Sbjct: 170 SISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQ 229
Query: 265 VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL-SASERVTMSARGSNHTLLIADV 323
+S T G + C PP WY+ L + + + + + L + +V
Sbjct: 230 EIKSGTVT-PGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNV 288
Query: 324 QPEDFGNYSCVADNSLG 340
E FGNY+CVA N LG
Sbjct: 289 TQEHFGNYTCVAANKLG 305
>BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein.
Length = 1100
Score = 89.0 bits (211), Expect = 3e-17
Identities = 70/232 (30%), Positives = 99/232 (42%), Gaps = 20/232 (8%)
Query: 124 VWETTRRITSEQHGNTNFRMI-FQDAGDYVCQISDRVARDQV---HTVEVLVPPSVRASP 179
V E +RR S++ GN + D G Y+C + + V +V T L V
Sbjct: 239 VAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEY 298
Query: 180 ETR---H----VTARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRLGEGPQ-LQLSR 228
E + H VTA +G +EC A GNPVPT+TW ++N S +RL + L++
Sbjct: 299 EPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQAVLEIPN 358
Query: 229 LERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADP 288
++ G+Y C +N G QLQV P + + G C P
Sbjct: 359 VQLDDAGIYECRAENSRGKNSF-RGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKP 417
Query: 289 PAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
W +N PLS RV M N L+I +V D G Y C+A+N G
Sbjct: 418 RPTYRWLKNGVPLSPQSRVEM----VNGVLMIHNVNQSDAGMYQCLAENKYG 465
Score = 59.7 bits (138), Expect = 2e-08
Identities = 48/159 (30%), Positives = 64/159 (40%), Gaps = 9/159 (5%)
Query: 194 LECRAAGNPVPTVTWHRL-------NDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVG 246
L C GNPVP+ W R +D L +G + + E G Y C N VG
Sbjct: 121 LNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQCLATNTVG 180
Query: 247 PPVVTEFQLQVLYPPEITVE-RSWVHTGEGFRAELVCTVLADPPAEV-SWYQNSFPLSAS 304
+ E LQ Y + RS V EG L+C+ P + SW N FP +
Sbjct: 181 SILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVA 240
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRAR 343
E L I+ VQ D G+Y C+ N++ AR
Sbjct: 241 EDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNAR 279
Score = 51.2 bits (117), Expect = 8e-06
Identities = 56/261 (21%), Positives = 104/261 (39%), Gaps = 21/261 (8%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVP-PSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
DAG Y C ++ +++L P+ + + + + V+EC+ G+P P
Sbjct: 452 DAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKP 511
Query: 205 TVTWH------RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVG-PPVVTEFQLQV 257
T++W R N + L +G L++ + G Y C +N G ++ ++
Sbjct: 512 TISWKKGDRAVRENKRIAILPDG-SLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKE 570
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS--WYQNSFPLSASER----VTMSA 311
E+T +R+ + GE L C + D +V+ W P+ E ++ A
Sbjct: 571 PTRIELTPKRTELTVGESI--VLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRA 628
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE--VSGRPGPARFT-SPPLARAPHS 368
+ S+ L+I ++ G Y C + E V G PGP + + +
Sbjct: 629 QASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITESTAT 688
Query: 369 YTLSFAVDSYPPLDELRLLYR 389
+ S A D++ P+ L R
Sbjct: 689 LSWSPAADNHSPISSYNLQAR 709
Score = 42.7 bits (96), Expect = 0.003
Identities = 52/216 (24%), Positives = 86/216 (39%), Gaps = 24/216 (11%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRH-VTARRGGAAVLECRAAGNPVP 204
+D+G Y C ++ V + S TR V+ R G VL C +
Sbjct: 166 KDSGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPE 225
Query: 205 TVTWHRLNDSSSRLGEGPQ---------LQLSRLERHHGGVYACTVDNGV------GPPV 249
+ N+ S + E + L +S+++ G Y C V N V PP
Sbjct: 226 IIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPT 285
Query: 250 VTEFQLQVL---YPPEITVERSWVHTG-EGFRAELVCTVLADPPAEVSWYQNSFPLSASE 305
+ + Y P+I V + T +G ++ C L +P ++W + + + +
Sbjct: 286 PLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKA 345
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGR 341
R+ R S L I +VQ +D G Y C A+NS G+
Sbjct: 346 RL----RKSQAVLEIPNVQLDDAGIYECRAENSRGK 377
>AL645724-1|CAI21858.1| 354|Homo sapiens neuronal growth regulator
1 protein.
Length = 354
Score = 89.0 bits (211), Expect = 3e-17
Identities = 57/197 (28%), Positives = 88/197 (44%), Gaps = 7/197 (3%)
Query: 147 DAGDYVCQI-SDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C + + R QVH + V VPP + + +T G L C A G P P
Sbjct: 112 DDGPYTCSVQTQHTPRTMQVH-LTVQVPPKIYDI--SNDMTVNEGTNVTLTCLATGKPEP 168
Query: 205 TVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEIT 264
+++W ++ S+ G L + + R G Y C+ +N V P V + ++ V + P I
Sbjct: 169 SISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQ 228
Query: 265 VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL-SASERVTMSARGSNHTLLIADV 323
+S T G + C PP WY+ L + + + + + L + +V
Sbjct: 229 EIKSGTVT-PGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNV 287
Query: 324 QPEDFGNYSCVADNSLG 340
E FGNY+CVA N LG
Sbjct: 288 TQEHFGNYTCVAANKLG 304
>AL627317-1|CAH72391.1| 354|Homo sapiens neuronal growth regulator
1 protein.
Length = 354
Score = 89.0 bits (211), Expect = 3e-17
Identities = 57/197 (28%), Positives = 88/197 (44%), Gaps = 7/197 (3%)
Query: 147 DAGDYVCQI-SDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C + + R QVH + V VPP + + +T G L C A G P P
Sbjct: 112 DDGPYTCSVQTQHTPRTMQVH-LTVQVPPKIYDI--SNDMTVNEGTNVTLTCLATGKPEP 168
Query: 205 TVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEIT 264
+++W ++ S+ G L + + R G Y C+ +N V P V + ++ V + P I
Sbjct: 169 SISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQ 228
Query: 265 VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL-SASERVTMSARGSNHTLLIADV 323
+S T G + C PP WY+ L + + + + + L + +V
Sbjct: 229 EIKSGTVT-PGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNV 287
Query: 324 QPEDFGNYSCVADNSLG 340
E FGNY+CVA N LG
Sbjct: 288 TQEHFGNYTCVAANKLG 304
>AL359821-1|CAH70913.1| 354|Homo sapiens neuronal growth regulator
1 protein.
Length = 354
Score = 89.0 bits (211), Expect = 3e-17
Identities = 57/197 (28%), Positives = 88/197 (44%), Gaps = 7/197 (3%)
Query: 147 DAGDYVCQI-SDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C + + R QVH + V VPP + + +T G L C A G P P
Sbjct: 112 DDGPYTCSVQTQHTPRTMQVH-LTVQVPPKIYDI--SNDMTVNEGTNVTLTCLATGKPEP 168
Query: 205 TVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEIT 264
+++W ++ S+ G L + + R G Y C+ +N V P V + ++ V + P I
Sbjct: 169 SISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQ 228
Query: 265 VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL-SASERVTMSARGSNHTLLIADV 323
+S T G + C PP WY+ L + + + + + L + +V
Sbjct: 229 EIKSGTVT-PGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNV 287
Query: 324 QPEDFGNYSCVADNSLG 340
E FGNY+CVA N LG
Sbjct: 288 TQEHFGNYTCVAANKLG 304
>AL356600-1|CAI23492.1| 354|Homo sapiens neuronal growth regulator
1 protein.
Length = 354
Score = 89.0 bits (211), Expect = 3e-17
Identities = 57/197 (28%), Positives = 88/197 (44%), Gaps = 7/197 (3%)
Query: 147 DAGDYVCQI-SDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C + + R QVH + V VPP + + +T G L C A G P P
Sbjct: 112 DDGPYTCSVQTQHTPRTMQVH-LTVQVPPKIYDI--SNDMTVNEGTNVTLTCLATGKPEP 168
Query: 205 TVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEIT 264
+++W ++ S+ G L + + R G Y C+ +N V P V + ++ V + P I
Sbjct: 169 SISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQ 228
Query: 265 VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL-SASERVTMSARGSNHTLLIADV 323
+S T G + C PP WY+ L + + + + + L + +V
Sbjct: 229 EIKSGTVT-PGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNV 287
Query: 324 QPEDFGNYSCVADNSLG 340
E FGNY+CVA N LG
Sbjct: 288 TQEHFGNYTCVAANKLG 304
>AL354949-1|CAI16869.1| 354|Homo sapiens neuronal growth regulator
1 protein.
Length = 354
Score = 89.0 bits (211), Expect = 3e-17
Identities = 57/197 (28%), Positives = 88/197 (44%), Gaps = 7/197 (3%)
Query: 147 DAGDYVCQI-SDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C + + R QVH + V VPP + + +T G L C A G P P
Sbjct: 112 DDGPYTCSVQTQHTPRTMQVH-LTVQVPPKIYDI--SNDMTVNEGTNVTLTCLATGKPEP 168
Query: 205 TVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEIT 264
+++W ++ S+ G L + + R G Y C+ +N V P V + ++ V + P I
Sbjct: 169 SISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQ 228
Query: 265 VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL-SASERVTMSARGSNHTLLIADV 323
+S T G + C PP WY+ L + + + + + L + +V
Sbjct: 229 EIKSGTVT-PGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNV 287
Query: 324 QPEDFGNYSCVADNSLG 340
E FGNY+CVA N LG
Sbjct: 288 TQEHFGNYTCVAANKLG 304
>AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein.
Length = 1026
Score = 89.0 bits (211), Expect = 3e-17
Identities = 70/232 (30%), Positives = 99/232 (42%), Gaps = 20/232 (8%)
Query: 124 VWETTRRITSEQHGNTNFRMI-FQDAGDYVCQISDRVARDQV---HTVEVLVPPSVRASP 179
V E +RR S++ GN + D G Y+C + + V +V T L V
Sbjct: 165 VAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEY 224
Query: 180 ETR---H----VTARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRLGEGPQ-LQLSR 228
E + H VTA +G +EC A GNPVPT+TW ++N S +RL + L++
Sbjct: 225 EPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQAVLEIPN 284
Query: 229 LERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADP 288
++ G+Y C +N G QLQV P + + G C P
Sbjct: 285 VQLDDAGIYECRAENSRGKNSF-RGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKP 343
Query: 289 PAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
W +N PLS RV M N L+I +V D G Y C+A+N G
Sbjct: 344 RPTYRWLKNGVPLSPQSRVEM----VNGVLMIHNVNQSDAGMYQCLAENKYG 391
Score = 59.7 bits (138), Expect = 2e-08
Identities = 48/159 (30%), Positives = 64/159 (40%), Gaps = 9/159 (5%)
Query: 194 LECRAAGNPVPTVTWHRL-------NDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVG 246
L C GNPVP+ W R +D L +G + + E G Y C N VG
Sbjct: 47 LNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQCLATNTVG 106
Query: 247 PPVVTEFQLQVLYPPEITVE-RSWVHTGEGFRAELVCTVLADPPAEV-SWYQNSFPLSAS 304
+ E LQ Y + RS V EG L+C+ P + SW N FP +
Sbjct: 107 SILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVA 166
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRAR 343
E L I+ VQ D G+Y C+ N++ AR
Sbjct: 167 EDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNAR 205
Score = 51.2 bits (117), Expect = 8e-06
Identities = 56/261 (21%), Positives = 104/261 (39%), Gaps = 21/261 (8%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVP-PSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
DAG Y C ++ +++L P+ + + + + V+EC+ G+P P
Sbjct: 378 DAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKP 437
Query: 205 TVTWH------RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVG-PPVVTEFQLQV 257
T++W R N + L +G L++ + G Y C +N G ++ ++
Sbjct: 438 TISWKKGDRAVRENKRIAILPDG-SLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKE 496
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS--WYQNSFPLSASER----VTMSA 311
E+T +R+ + GE L C + D +V+ W P+ E ++ A
Sbjct: 497 PTRIELTPKRTELTVGESI--VLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRA 554
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE--VSGRPGPARFT-SPPLARAPHS 368
+ S+ L+I ++ G Y C + E V G PGP + + +
Sbjct: 555 QASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITESTAT 614
Query: 369 YTLSFAVDSYPPLDELRLLYR 389
+ S A D++ P+ L R
Sbjct: 615 LSWSPAADNHSPISSYNLQAR 635
Score = 42.7 bits (96), Expect = 0.003
Identities = 52/216 (24%), Positives = 86/216 (39%), Gaps = 24/216 (11%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRH-VTARRGGAAVLECRAAGNPVP 204
+D+G Y C ++ V + S TR V+ R G VL C +
Sbjct: 92 KDSGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPE 151
Query: 205 TVTWHRLNDSSSRLGEGPQ---------LQLSRLERHHGGVYACTVDNGV------GPPV 249
+ N+ S + E + L +S+++ G Y C V N V PP
Sbjct: 152 IIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPT 211
Query: 250 VTEFQLQVL---YPPEITVERSWVHTG-EGFRAELVCTVLADPPAEVSWYQNSFPLSASE 305
+ + Y P+I V + T +G ++ C L +P ++W + + + +
Sbjct: 212 PLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKA 271
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGR 341
R+ R S L I +VQ +D G Y C A+NS G+
Sbjct: 272 RL----RKSQAVLEIPNVQLDDAGIYECRAENSRGK 303
>AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein.
Length = 1100
Score = 89.0 bits (211), Expect = 3e-17
Identities = 70/232 (30%), Positives = 99/232 (42%), Gaps = 20/232 (8%)
Query: 124 VWETTRRITSEQHGNTNFRMI-FQDAGDYVCQISDRVARDQV---HTVEVLVPPSVRASP 179
V E +RR S++ GN + D G Y+C + + V +V T L V
Sbjct: 239 VAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEY 298
Query: 180 ETR---H----VTARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRLGEGPQ-LQLSR 228
E + H VTA +G +EC A GNPVPT+TW ++N S +RL + L++
Sbjct: 299 EPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQAVLEIPN 358
Query: 229 LERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADP 288
++ G+Y C +N G QLQV P + + G C P
Sbjct: 359 VQLDDAGIYECRAENSRGKNSF-RGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKP 417
Query: 289 PAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
W +N PLS RV M N L+I +V D G Y C+A+N G
Sbjct: 418 RPTYRWLKNGVPLSPQSRVEM----VNGVLMIHNVNQSDAGMYQCLAENKYG 465
Score = 59.7 bits (138), Expect = 2e-08
Identities = 48/159 (30%), Positives = 64/159 (40%), Gaps = 9/159 (5%)
Query: 194 LECRAAGNPVPTVTWHRL-------NDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVG 246
L C GNPVP+ W R +D L +G + + E G Y C N VG
Sbjct: 121 LNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQCLATNTVG 180
Query: 247 PPVVTEFQLQVLYPPEITVE-RSWVHTGEGFRAELVCTVLADPPAEV-SWYQNSFPLSAS 304
+ E LQ Y + RS V EG L+C+ P + SW N FP +
Sbjct: 181 SILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVA 240
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRAR 343
E L I+ VQ D G+Y C+ N++ AR
Sbjct: 241 EDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNAR 279
Score = 51.2 bits (117), Expect = 8e-06
Identities = 56/261 (21%), Positives = 104/261 (39%), Gaps = 21/261 (8%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVP-PSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
DAG Y C ++ +++L P+ + + + + V+EC+ G+P P
Sbjct: 452 DAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKP 511
Query: 205 TVTWH------RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVG-PPVVTEFQLQV 257
T++W R N + L +G L++ + G Y C +N G ++ ++
Sbjct: 512 TISWKKGDRAVRENKRIAILPDG-SLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKE 570
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS--WYQNSFPLSASER----VTMSA 311
E+T +R+ + GE L C + D +V+ W P+ E ++ A
Sbjct: 571 PTRIELTPKRTELTVGESI--VLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRA 628
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE--VSGRPGPARFT-SPPLARAPHS 368
+ S+ L+I ++ G Y C + E V G PGP + + +
Sbjct: 629 QASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITESTAT 688
Query: 369 YTLSFAVDSYPPLDELRLLYR 389
+ S A D++ P+ L R
Sbjct: 689 LSWSPAADNHSPISSYNLQAR 709
Score = 42.7 bits (96), Expect = 0.003
Identities = 52/216 (24%), Positives = 86/216 (39%), Gaps = 24/216 (11%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRH-VTARRGGAAVLECRAAGNPVP 204
+D+G Y C ++ V + S TR V+ R G VL C +
Sbjct: 166 KDSGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPE 225
Query: 205 TVTWHRLNDSSSRLGEGPQ---------LQLSRLERHHGGVYACTVDNGV------GPPV 249
+ N+ S + E + L +S+++ G Y C V N V PP
Sbjct: 226 IIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPT 285
Query: 250 VTEFQLQVL---YPPEITVERSWVHTG-EGFRAELVCTVLADPPAEVSWYQNSFPLSASE 305
+ + Y P+I V + T +G ++ C L +P ++W + + + +
Sbjct: 286 PLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKA 345
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGR 341
R+ R S L I +VQ +D G Y C A+NS G+
Sbjct: 346 RL----RKSQAVLEIPNVQLDDAGIYECRAENSRGK 377
>AL360004-4|CAI16954.2| 746|Homo sapiens novel protein similar to
hemicentin (LOC392395) protein.
Length = 746
Score = 88.6 bits (210), Expect = 4e-17
Identities = 68/247 (27%), Positives = 109/247 (44%), Gaps = 21/247 (8%)
Query: 134 EQHGNTNFRMIFQ---DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGG 190
++ GN+++ ++ + G Y C R + V+ P + P +VT G
Sbjct: 437 QESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAP-NVTVSPGE 495
Query: 191 AAVLECRAAGNPVPTVTWHR----LNDSSSRLGE--GPQLQLSRLERHHGGVYACTVDNG 244
AVL CR G +TW R L S+ R+ + L++S + GG Y C N
Sbjct: 496 TAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNA 555
Query: 245 VGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
G + + L V P++++ S H +G ++ C+ P +SW + S L
Sbjct: 556 NGVTRASVWLL-VREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQED 614
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR 364
R+ + A+G TL+I V PED GNYSC A N +G + V + +T PP
Sbjct: 615 SRIHVDAQG---TLIIQGVAPEDAGNYSCQATNEVGTDQETVTL-------YYTDPPSVS 664
Query: 365 APHSYTL 371
A ++ L
Sbjct: 665 AVNAVVL 671
Score = 73.3 bits (172), Expect = 2e-12
Identities = 69/276 (25%), Positives = 107/276 (38%), Gaps = 21/276 (7%)
Query: 88 ITDVGPQIRYTVDVTIYENSETSVALAILGATGHTNVWETTRRITSEQHGNTN------- 140
+TD PQ+ +VT+ ++ +LG + W R+ G
Sbjct: 476 VTDPPPQLVPAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSL 535
Query: 141 --FRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRA 198
+I D G Y C S+ + +V +LV + + S T +G + C A
Sbjct: 536 EISGIIPTDGGRYQCVASNANGVTRA-SVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSA 594
Query: 199 AGNPVPTVTWHRLNDS---SSRLGEGPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
+G P P ++W R + + SR+ Q L + + G Y+C N VG T
Sbjct: 595 SGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQET-V 653
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
L PP ++ + V G A LVC PP V WY+ E +
Sbjct: 654 TLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGL-----EMILAPEGS 708
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
S+ L I Q D G Y+C A N LG A ++++
Sbjct: 709 SSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLA 744
>AK092307-1|BAC03858.1| 354|Homo sapiens protein ( Homo sapiens
cDNA FLJ34988 fis, clone OCBBF2011021, highly similar to
KILON PROTEIN PRECURSOR. ).
Length = 354
Score = 87.8 bits (208), Expect = 8e-17
Identities = 57/197 (28%), Positives = 87/197 (44%), Gaps = 7/197 (3%)
Query: 147 DAGDYVCQI-SDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
D G Y C + + R QVH + V VPP + + +T G L C A G P P
Sbjct: 112 DDGPYTCSVQTQHTPRTMQVH-LTVQVPPKIYDI--SNDMTVNEGTNVTLTCLATGKPEP 168
Query: 205 TVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEIT 264
++W ++ S+ G L + + R G Y C+ +N V P V + ++ V + P I
Sbjct: 169 FISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQ 228
Query: 265 VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL-SASERVTMSARGSNHTLLIADV 323
+S T G + C PP WY+ L + + + + + L + +V
Sbjct: 229 EIKSGTVT-PGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNV 287
Query: 324 QPEDFGNYSCVADNSLG 340
E FGNY+CVA N LG
Sbjct: 288 TQEHFGNYTCVAANKLG 304
>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
Length = 2673
Score = 87.8 bits (208), Expect = 8e-17
Identities = 67/211 (31%), Positives = 92/211 (43%), Gaps = 17/211 (8%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G YVC+ + RD + + V VPPS+ PE + L C A G P PT
Sbjct: 162 DTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG-PEREVIVETISNPVTLTCDATGIPPPT 220
Query: 206 VTW----HRLNDSSSR----LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W R+ +S S L G +LQ++R + G Y C N G F L +
Sbjct: 221 IAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYF-LSI 279
Query: 258 LYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA--SERVTMSARG 313
PP + S V G ELVC P + W ++ P+++ +ER+ +SA G
Sbjct: 280 QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG 339
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
S TL I D G Y+CVA N G R
Sbjct: 340 S--TLNIYGALTSDTGKYTCVATNPAGEEDR 368
Score = 87.4 bits (207), Expect = 1e-16
Identities = 59/203 (29%), Positives = 88/203 (43%), Gaps = 12/203 (5%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D Y C S+R D H ++V PP++ S T +T +G + + C G P P+
Sbjct: 445 DVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPS 504
Query: 206 VTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W R L+ + G LQL + E G Y C N G V F L+VL
Sbjct: 505 MAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG-EVSKHFILKVLE 563
Query: 260 PPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + E + EL C P +++W ++ PL +++V G
Sbjct: 564 PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQV--QTLGGGEV 621
Query: 318 LLIADVQPEDFGNYSCVADNSLG 340
L I+ Q ED G Y+C+A + G
Sbjct: 622 LRISTAQVEDTGRYTCLASSPAG 644
Score = 85.8 bits (203), Expect = 3e-16
Identities = 73/280 (26%), Positives = 116/280 (41%), Gaps = 22/280 (7%)
Query: 91 VGPQIRYTVD-VTIYENSETSVALAILGATGHTNVWETTR--------RITSEQHGNTNF 141
V P+IR T T+ ENS+ + G W+ + T+E +G
Sbjct: 1205 VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELIL 1264
Query: 142 R-MIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ +D+G Y C +++ A + HTV + V + V+ +G L C+A G
Sbjct: 1265 ENVVLEDSGFYTC-VANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATG 1323
Query: 201 NPVPTVTWHRLND----SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P+P +TW N+ + +L + R+ + G Y CT +N VG F +
Sbjct: 1324 IPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGF-VY 1382
Query: 257 VLYPPEITVE--RSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP + W+ G A L C V DP + W + + S R+ GS
Sbjct: 1383 VKEPPVFKGDYPSHWIEPLGG-NAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGS 1441
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
L I ED G+Y+CVA N G R + ++ + P
Sbjct: 1442 ---LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 1478
Score = 85.8 bits (203), Expect = 3e-16
Identities = 61/213 (28%), Positives = 89/213 (41%), Gaps = 11/213 (5%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGN 201
R+ +D+G YVC + V + + P V H GG A+L C G+
Sbjct: 1355 RVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSHWIEPLGGNAILNCEVKGD 1414
Query: 202 PVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQL 255
P PT+ W+R ++ +LG G L + G Y C N G V L
Sbjct: 1415 PTPTIQWNRKGVDIEISHRIRQLGNG-SLAIYGTVNEDAGDYTCVATNEAG-VVERSMSL 1472
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
+ PP IT+E G + L C +P ++W + +S +RV + SN
Sbjct: 1473 TLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL---SN 1529
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
++L IAD Q ED + CVA N +G V V
Sbjct: 1530 NSLYIADAQKEDTSEFECVARNLMGSVLVRVPV 1562
Score = 82.6 bits (195), Expect = 3e-15
Identities = 57/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 128 TRRITSEQHGNTN--FRMIFQDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHV 184
T RI +G+T + + D G Y C ++ D++ + V V P++R + +
Sbjct: 330 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEK 389
Query: 185 TARRGGAAV-LECRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVY 237
++ +ECRA G P P + W + L+ L G +++ R + VY
Sbjct: 390 LMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVY 449
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEI--TVERSWVHTGEGFRAELVCTVLADPPAEVSWY 295
C N G + LQV PP + ++ + +G + C P ++W
Sbjct: 450 TCVASNRAGVDN-KHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWL 508
Query: 296 QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
++ PL +T+S G LL A+ ED G Y+C+A N G +H
Sbjct: 509 RDGQPLGLDAHLTVSTHGMVLQLLKAET--EDSGKYTCIASNEAGEVSKH 556
Score = 81.8 bits (193), Expect = 5e-15
Identities = 60/219 (27%), Positives = 95/219 (43%), Gaps = 11/219 (5%)
Query: 147 DAGDYVC-QISDRVARDQVHTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNPV 203
D G+Y C I+ + ++ V VPPS++ S V R G + LE + P
Sbjct: 67 DGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLEXESNAVPP 126
Query: 204 PTVTWHR----LNDSS--SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P +TW++ + +S+ L +G L + + E G Y C N G F L V
Sbjct: 127 PVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDD-KNFHLNV 185
Query: 258 LYPPEIT-VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP I ER + L C PP ++W +N + S+ + +
Sbjct: 186 YVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGS 245
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L IA Q D GNY+C+A N G+A+++ +S + P+
Sbjct: 246 KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPS 284
Score = 79.4 bits (187), Expect = 3e-14
Identities = 59/200 (29%), Positives = 84/200 (42%), Gaps = 13/200 (6%)
Query: 148 AGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
AG Y C + H T+ V PP ++ P HV +L C A G P P +
Sbjct: 1000 AGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNN--PILLPCEATGTPSPFI 1057
Query: 207 TWHR----LNDSSSRLGEGPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
TW + +N S P LQ+SR R G Y C N G + + +L V P
Sbjct: 1058 TWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGT-ALGKIKLNVQVP 1116
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I+ L C PP +++W+++ + S R + + GS L I
Sbjct: 1117 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGS---LQI 1173
Query: 321 ADVQPEDFGNYSCVADNSLG 340
VQP D G+Y+C+A N G
Sbjct: 1174 TFVQPGDAGHYTCMAANVAG 1193
Score = 75.8 bits (178), Expect = 3e-13
Identities = 64/227 (28%), Positives = 91/227 (40%), Gaps = 18/227 (7%)
Query: 146 QDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G Y C S D + + V V VPP++ + E R +T R LEC++ P P
Sbjct: 630 EDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPP 689
Query: 205 TVTWHRLND---SSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+TW R + ++ R L G LQ++ + Y C N G EF L V
Sbjct: 690 VITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAG-KTTREFILTVN 748
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSARGSNHT 317
PP I + L C P ++W ++ L+ + R ++ G H
Sbjct: 749 VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH- 807
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARR------HVEVSGRPGPARFT 358
I D G Y C+A N+ G RR HV S PGP T
Sbjct: 808 --IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMT 852
Score = 71.3 bits (167), Expect = 7e-12
Identities = 75/306 (24%), Positives = 120/306 (39%), Gaps = 31/306 (10%)
Query: 100 DVTIYENSETSVALAILGATGHTNVWETTRRITSEQHGNTNFRMI-----------FQDA 148
++T+ N +T++A G + W + + ++R++ D
Sbjct: 850 NMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 909
Query: 149 GDYVCQISDRVARDQVHTVE--VLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
Y C +++ A D TV+ V VPPS+ P VT + AV+ C A+G P P++
Sbjct: 910 ATYECTVTNG-AGDDKRTVDLTVQVPPSIADEPTDFLVT--KHAPAVITCTASGVPFPSI 966
Query: 207 TWHRLNDSSSRLGEGPQL------QLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
W + G+G ++ ++ + +H G Y C N G L V P
Sbjct: 967 HWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGS-AHRHVTLHVHEP 1025
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I + S +H L C P ++W + ++ S R A + L I
Sbjct: 1026 PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGR--NHAVLPSGGLQI 1083
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR----APHSYTLSFAVD 376
+ ED G Y CVA N G A ++++ + P SP L TLS D
Sbjct: 1084 SRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPV--ISPHLKEYVIAVDKPITLSCEAD 1141
Query: 377 SYPPLD 382
PP D
Sbjct: 1142 GLPPPD 1147
Score = 70.9 bits (166), Expect = 1e-11
Identities = 61/210 (29%), Positives = 86/210 (40%), Gaps = 16/210 (7%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C ++ D+ ++V VPPS+ P ++T L C A G P P+
Sbjct: 815 DTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPT--NMTVIVNVQTTLACEATGIPKPS 872
Query: 206 VTW----HRLN----DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W H LN +S RL L + Y CTV NG G T L V
Sbjct: 873 INWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRT-VDLTV 931
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL-SASERVTMSARGSNH 316
PP I E + + A + CT P + W +N L + + + G+
Sbjct: 932 QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGA-- 989
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHV 346
+ I Q G Y+CVA N+ G A RHV
Sbjct: 990 -IEILATQLNHAGRYTCVARNAAGSAHRHV 1018
Score = 69.7 bits (163), Expect = 2e-11
Identities = 56/201 (27%), Positives = 83/201 (41%), Gaps = 14/201 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
DAG Y C ++ T + V VPP +R++ H T A+L C A G P P
Sbjct: 1180 DAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEG--HYTVNENSQAILPCVADGIPTPA 1237
Query: 206 VTWHRLND-SSSRLGEGP-----QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W + N ++ LG+ +L L + G Y C +N G T L V
Sbjct: 1238 INWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHT-VSLTVHV 1296
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
P T V +G + L C P +++W N+ + A + + L+
Sbjct: 1297 LPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAH----FDSVNGHSELV 1352
Query: 320 IADVQPEDFGNYSCVADNSLG 340
I V ED G Y C A+NS+G
Sbjct: 1353 IERVSKEDSGTYVCTAENSVG 1373
Score = 69.3 bits (162), Expect = 3e-11
Identities = 54/223 (24%), Positives = 90/223 (40%), Gaps = 14/223 (6%)
Query: 147 DAGDYVC---QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D +Y C I+ + R+ + TV V PP+++ P++ + + + VLEC A G P
Sbjct: 724 DTANYTCVASNIAGKTTREFILTVNV--PPNIKGGPQSLVILLNK--STVLECIAEGVPT 779
Query: 204 PTVTWHR----LNDSSSRLG--EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P +TW + L + +R E L + G Y C N G LQV
Sbjct: 780 PRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDR-RRIDLQV 838
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + + + L C P ++W +N L+ + S+ +
Sbjct: 839 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS 898
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
L+I +D Y C N G +R V+++ + P+ P
Sbjct: 899 LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEP 941
Score = 68.1 bits (159), Expect = 7e-11
Identities = 55/211 (26%), Positives = 81/211 (38%), Gaps = 15/211 (7%)
Query: 147 DAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D+G+Y C S+ + Q + + + VPPSV + V+ G L C A G P P
Sbjct: 256 DSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 315
Query: 206 VTWHR-----LNDSSSRL---GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W + + + R+ G L + G Y C N G F L V
Sbjct: 316 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRI-FNLNV 374
Query: 258 LYPPEITV---ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
P I E + T + C PP +++W +N PL S + + A G
Sbjct: 375 YVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG- 433
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
+ I Q D Y+CVA N G +H
Sbjct: 434 -QVIRIVRAQVSDVAVYTCVASNRAGVDNKH 463
Score = 66.9 bits (156), Expect = 2e-10
Identities = 55/180 (30%), Positives = 78/180 (43%), Gaps = 14/180 (7%)
Query: 172 PPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQ 225
PPSV P++ ++T L C +G P P ++W + LN ++ + G LQ
Sbjct: 1 PPSV-IGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQ 59
Query: 226 LSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEI----TVERSWVHTGEGFRAELV 281
+ R + GG Y C N G +F L V PP I + S V+ EG L
Sbjct: 60 IIRAKVSDGGEYTCIAINQAGES-KKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLE 118
Query: 282 CTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGR 341
A PP ++WY+N ++ S V + A G L I + D G Y C A N GR
Sbjct: 119 XESNAVPPPVITWYKNGRMITESTHVEILADG--QMLHIKKAEVSDTGQYVCRAINVAGR 176
Score = 48.8 bits (111), Expect = 4e-05
Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 126 ETTRRITSEQHGNTN-FRMIFQDAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRH 183
E + RI +G+ + + +DAGDY C ++ ++ ++ + PP + P
Sbjct: 1429 EISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETV 1488
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLNDSSS 216
+ A GG +L C+A G P PT+TW R S S
Sbjct: 1489 INA--GGKIILNCQATGEPQPTITWSRQGHSIS 1519
Score = 41.9 bits (94), Expect = 0.005
Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 2/65 (3%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C V PP ++SW +N P+ + + G TL I + D G Y+C+A N
Sbjct: 22 LTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGG--RTLQIIRAKVSDGGEYTCIAINQA 79
Query: 340 GRARR 344
G +++
Sbjct: 80 GESKK 84
>AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608
protein.
Length = 2623
Score = 86.6 bits (205), Expect = 2e-16
Identities = 74/244 (30%), Positives = 103/244 (42%), Gaps = 19/244 (7%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
R+ QD G Y+C S+ D +H T+ V+ P T+ +T G L+CRA G
Sbjct: 1712 RVEIQDRGQYLCSASNLFGTDHLHVTLSVVSYPPRILERRTKEITVHSGSTVELKCRAEG 1771
Query: 201 NPVPTVTWHRLNDS-SSRLGEGPQ---------LQLSRLERHHGGVYACTVDN-GVGPPV 249
P PTVTW N + S +G + L L L + G Y C N G +
Sbjct: 1772 RPSPTVTWILANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFYKCVASNPGGQDSL 1831
Query: 250 VTEFQLQVLYPPEITVERSWVHTGE-GFRAELVCTVLADPPAEVSWYQNSFPLSASERVT 308
+ + Q+ + PP I +R V G G +L CT P V W + + T
Sbjct: 1832 LVKIQV-IAAPPVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFT 1890
Query: 309 MSA--RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAP 366
S SN TL I ++ D G Y C+A +S G RR V ++ R TSP + A
Sbjct: 1891 NSKLFLFSNGTLYIRNLASSDRGTYECIATSSTGSERRVVMLTME---ERVTSPRIEAAS 1947
Query: 367 HSYT 370
T
Sbjct: 1948 QKRT 1951
Score = 67.3 bits (157), Expect = 1e-10
Identities = 66/250 (26%), Positives = 99/250 (39%), Gaps = 22/250 (8%)
Query: 130 RITSEQHGNTNFRMI-FQDAGDYVC----QISDRVARDQVHTVEVLVPPSVRASPETRHV 184
RIT ++G R + D+ D++C + + V Q+ +E+L P+ R +P +
Sbjct: 2289 RITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFR-NPFNEKI 2347
Query: 185 TARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQ-----------LSRLERHH 233
A+ G + L C GNP P + W + + +R GPQ +S+ R
Sbjct: 2348 VAQLGKSTALNCSVDGNPPPEIIW--ILPNGTRFSNGPQSYQYLIASNGSFIISKTTRED 2405
Query: 234 GGVYACTVDNGVGPPVVTEFQLQVLYPPEI-TVERSWVHTGEGFRAELVCTVLADPPAEV 292
G Y C N VG + L++ P I T V G L C P +
Sbjct: 2406 AGKYRCAARNKVGY-IEKLVILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNI 2464
Query: 293 SWYQNS-FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR 351
W S + + + N TL+I + D GNY C A NS+G V V
Sbjct: 2465 KWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIV 2524
Query: 352 PGPARFTSPP 361
P R T+ P
Sbjct: 2525 AYPPRITNRP 2534
Score = 60.5 bits (140), Expect = 1e-08
Identities = 69/283 (24%), Positives = 113/283 (39%), Gaps = 25/283 (8%)
Query: 128 TRRITSEQHGNTNFRMI-FQDAGDYVCQISDRVARDQ--VHTVEVLVPPSVRASPETRHV 184
TRR T +G F + + GDY C + + +D+ VH + P +R S +T
Sbjct: 2093 TRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTVITAAPRIRQSNKTNK- 2151
Query: 185 TARRGGAAVLECRAAGNPVPTVTW-HRLNDSSS------RLGEGPQLQLSRLERHHGGVY 237
+ G AVL+C G+P P + W ND S L +++++ G Y
Sbjct: 2152 RIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVKLLDSGEY 2211
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEIT----VERSWVHTG--EGFRAELVCTVLADPPAE 291
C N G ++L V+ P + R+ + + C P E
Sbjct: 2212 VCVARNPSGDD-TKMYKLDVVSKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPE 2270
Query: 292 VSWYQ-NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA-----RRH 345
V W ++ L+A + N TL I +V+ D ++ CVA N G +
Sbjct: 2271 VMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEV 2330
Query: 346 VEVSGRPGPAR-FTSPPLARAPHSYTLSFAVDSYPPLDELRLL 387
+E+ RP F +A+ S L+ +VD PP + + +L
Sbjct: 2331 LEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWIL 2373
Score = 58.4 bits (135), Expect = 5e-08
Identities = 49/163 (30%), Positives = 71/163 (43%), Gaps = 13/163 (7%)
Query: 192 AVLECRAAGNPVPTVTWHRL--------NDSSSRLGEGPQ--LQLSRLERHHGGVYACTV 241
A L C A GNP+PT+ W R+ +SR+ P L + R+E G Y C+
Sbjct: 1666 AFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNGTLSIQRVEIQDRGQYLCSA 1725
Query: 242 DNGVGPPVVTEFQLQVLYPPEITVERS-WVHTGEGFRAELVCTVLADPPAEVSW-YQNSF 299
N G + V YPP I R+ + G EL C P V+W N
Sbjct: 1726 SNLFGTDHLHVTLSVVSYPPRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQT 1785
Query: 300 PLSASERVTMSARGS-NHTLLIADVQPEDFGNYSCVADNSLGR 341
+S S + + A + + TL++ ++ D G Y CVA N G+
Sbjct: 1786 VVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFYKCVASNPGGQ 1828
Score = 52.0 bits (119), Expect = 5e-06
Identities = 57/246 (23%), Positives = 88/246 (35%), Gaps = 16/246 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C S+ +D + ++V+ P V + + G + L C A G P P+
Sbjct: 1814 DRGFYKCVASNPGGQDSLLVKIQVIAAPPVILEQRRQVIVGTWGESLKLPCTAKGTPQPS 1873
Query: 206 VTWH----------RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPP---VVTE 252
V W + +S L L + L G Y C + G V+
Sbjct: 1874 VYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYECIATSSTGSERRVVMLT 1933
Query: 253 FQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSW-YQNSFPLSASERVTMSA 311
+ +V P + G + L C+ +P ++ W + + RV
Sbjct: 1934 MEERVTSPRIEAASQKRTEVNFGDKLLLNCSATGEPKPQIMWRLPSKAVVDQQHRVGSWI 1993
Query: 312 RG-SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSYT 370
N +L I V +D G Y CVA N +G + VS R PA+ R +
Sbjct: 1994 HVYPNGSLFIGSVTEKDSGVYLCVARNKMGDDLILMHVSLRLKPAKIDHKQYFRKQVLHG 2053
Query: 371 LSFAVD 376
F VD
Sbjct: 2054 KDFQVD 2059
Score = 50.0 bits (114), Expect = 2e-05
Identities = 45/168 (26%), Positives = 69/168 (41%), Gaps = 21/168 (12%)
Query: 189 GGAAVLECRAAGNPVPTVTWHRLNDSSSR-----------LGEGPQLQLSRLERHHGGVY 237
GG L C G+P P V W + S R + + +L+L + GVY
Sbjct: 490 GGTVGLNCPGQGDPTPHVDWLLADGSKVRAPYVSEDGRILIDKSGKLELQMADSFDTGVY 549
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGE--GFRAELVCTVLADPPAEVSWY 295
C N ++T +++ V+ P + + +H G +L C P A +SW
Sbjct: 550 HCISSNYDDADILT-YRITVVEPLVEAYQENGIHHTVFIGETLDLPCHSTGIPDASISWV 608
Query: 296 ---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
N S+ ++ ++ N TL I V P+D G Y CVA N G
Sbjct: 609 IPGNNVLYQSSRDKKVLN----NGTLRILQVTPKDQGYYRCVAANPSG 652
Score = 47.6 bits (108), Expect = 1e-04
Identities = 52/215 (24%), Positives = 85/215 (39%), Gaps = 23/215 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D+G Y+C +++ D + V + + P+ + G ++C+A+G+PVP
Sbjct: 2009 KDSGVYLCVARNKMGDDLILMHVSLRLKPAKIDHKQYFRKQVLHGKDFQVDCKASGSPVP 2068
Query: 205 TVTWH-----------RLNDSSSR-----LGEGPQLQLSRLERHHGGVYACTVDNGVGPP 248
++W + +DS R L L +++ G Y C N +G
Sbjct: 2069 EISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKD 2128
Query: 249 VVTEFQLQVLYPPEI-TVERSWVHTGEGFRAELVCTVLADPPAEVSWY--QNSFPLSASE 305
+ + P I ++ G A L C V DP ++ W N + +
Sbjct: 2129 EMKVHLTVITAAPRIRQSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSID 2188
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
R T A GS L I V+ D G Y CVA N G
Sbjct: 2189 RYTFHANGS---LTINKVKLLDSGEYVCVARNPSG 2220
Score = 47.2 bits (107), Expect = 1e-04
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 18/127 (14%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLV---PPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D G+Y+C+ + V + TV V++ PP + P R + R G A L C A G P
Sbjct: 2500 DRGNYICKAQNSVGHTLI-TVPVMIVAYPPRITNRPP-RSIVTRTGAAFQLHCVALGVPK 2557
Query: 204 PTVTW----HRLNDSSS--RLGEGPQLQL------SRLERHHGGVYACTVDNGVGPPVVT 251
P +TW H L ++S R QL L + G+Y CT N +G
Sbjct: 2558 PEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDYAA 2617
Query: 252 EFQLQVL 258
+ +QV+
Sbjct: 2618 TY-IQVI 2623
Score = 34.7 bits (76), Expect = 0.76
Identities = 34/127 (26%), Positives = 48/127 (37%), Gaps = 6/127 (4%)
Query: 278 AELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG--SNHTLLIADVQPEDFGNYSCVA 335
A L C + +P + W + L S+R S N TL I V+ +D G Y C A
Sbjct: 1666 AFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNGTLSIQRVEIQDRGQYLCSA 1725
Query: 336 DNSLGRARRHVEVSGRPGPARF----TSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQL 391
N G HV +S P R T + + L + P +L Q
Sbjct: 1726 SNLFGTDHLHVTLSVVSYPPRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQT 1785
Query: 392 AINESFQ 398
++ES Q
Sbjct: 1786 VVSESSQ 1792
>AK128160-1|BAC87305.1| 632|Homo sapiens protein ( Homo sapiens
cDNA FLJ46283 fis, clone TESTI4031173. ).
Length = 632
Score = 86.6 bits (205), Expect = 2e-16
Identities = 74/244 (30%), Positives = 103/244 (42%), Gaps = 19/244 (7%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
R+ QD G Y+C S+ D +H T+ V+ P T+ +T G L+CRA G
Sbjct: 339 RVEIQDRGQYLCSASNLFGTDHLHVTLSVVSYPPRILERRTKEITVHSGSTVELKCRAEG 398
Query: 201 NPVPTVTWHRLNDS-SSRLGEGPQ---------LQLSRLERHHGGVYACTVDN-GVGPPV 249
P PTVTW N + S +G + L L L + G Y C N G +
Sbjct: 399 RPSPTVTWILANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFYKCVASNPGGQDSL 458
Query: 250 VTEFQLQVLYPPEITVERSWVHTGE-GFRAELVCTVLADPPAEVSWYQNSFPLSASERVT 308
+ + Q+ + PP I +R V G G +L CT P V W + + T
Sbjct: 459 LVKIQV-IAAPPVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFT 517
Query: 309 MSA--RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAP 366
S SN TL I ++ D G Y C+A +S G RR V ++ R TSP + A
Sbjct: 518 NSKLFLFSNGTLYIRNLASSDRGTYECIATSSTGSERRVVMLTME---ERVTSPRIEAAS 574
Query: 367 HSYT 370
T
Sbjct: 575 QKRT 578
Score = 58.4 bits (135), Expect = 5e-08
Identities = 49/163 (30%), Positives = 71/163 (43%), Gaps = 13/163 (7%)
Query: 192 AVLECRAAGNPVPTVTWHRL--------NDSSSRLGEGPQ--LQLSRLERHHGGVYACTV 241
A L C A GNP+PT+ W R+ +SR+ P L + R+E G Y C+
Sbjct: 293 AFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNGTLSIQRVEIQDRGQYLCSA 352
Query: 242 DNGVGPPVVTEFQLQVLYPPEITVERS-WVHTGEGFRAELVCTVLADPPAEVSW-YQNSF 299
N G + V YPP I R+ + G EL C P V+W N
Sbjct: 353 SNLFGTDHLHVTLSVVSYPPRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQT 412
Query: 300 PLSASERVTMSARGS-NHTLLIADVQPEDFGNYSCVADNSLGR 341
+S S + + A + + TL++ ++ D G Y CVA N G+
Sbjct: 413 VVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFYKCVASNPGGQ 455
Score = 34.7 bits (76), Expect = 0.76
Identities = 34/127 (26%), Positives = 48/127 (37%), Gaps = 6/127 (4%)
Query: 278 AELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG--SNHTLLIADVQPEDFGNYSCVA 335
A L C + +P + W + L S+R S N TL I V+ +D G Y C A
Sbjct: 293 AFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNGTLSIQRVEIQDRGQYLCSA 352
Query: 336 DNSLGRARRHVEVSGRPGPARF----TSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQL 391
N G HV +S P R T + + L + P +L Q
Sbjct: 353 SNLFGTDHLHVTLSVVSYPPRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQT 412
Query: 392 AINESFQ 398
++ES Q
Sbjct: 413 VVSESSQ 419
>AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat
protein LRIG1 protein.
Length = 1093
Score = 85.4 bits (202), Expect = 4e-16
Identities = 59/222 (26%), Positives = 94/222 (42%), Gaps = 16/222 (7%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTVEVLVP--PSVRASPETRHVTARRGGAAVLECRAA 199
++ F G Y C I++ H + V PS +P +T R A LEC A
Sbjct: 566 QVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPSFTKTPHD--ITIRTTTVARLECAAT 623
Query: 200 GNPVPTVTWHRLNDSSSRLGEGPQLQ---------LSRLERHHGGVYACTVDNGVGPPVV 250
G+P P + W + + ++ ++ ++ GVY+CT N G +
Sbjct: 624 GHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQNSAGS-IS 682
Query: 251 TEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
L VL P + V G L C +PP ++W++ PLS +ER ++
Sbjct: 683 ANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLT 742
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRP 352
N L++ +V ED G Y+C N+LG R H ++S P
Sbjct: 743 P--DNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVLP 782
Score = 47.6 bits (108), Expect = 1e-04
Identities = 33/120 (27%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCT 283
L L ++ H G Y C + N G + +L V P T + A L C
Sbjct: 562 LHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPSFTKTPHDITIRTTTVARLECA 621
Query: 284 VLADPPAEVSWYQNS---FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
P +++W ++ FP + R M + I DV+ +D G YSC A NS G
Sbjct: 622 ATGHPNPQIAWQKDGGTDFPAARERR--MHVMPDDDVFFITDVKIDDAGVYSCTAQNSAG 679
>AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein
LRIG1 protein.
Length = 1093
Score = 85.4 bits (202), Expect = 4e-16
Identities = 59/222 (26%), Positives = 94/222 (42%), Gaps = 16/222 (7%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTVEVLVP--PSVRASPETRHVTARRGGAAVLECRAA 199
++ F G Y C I++ H + V PS +P +T R A LEC A
Sbjct: 566 QVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPSFTKTPHD--ITIRTTTVARLECAAT 623
Query: 200 GNPVPTVTWHRLNDSSSRLGEGPQLQ---------LSRLERHHGGVYACTVDNGVGPPVV 250
G+P P + W + + ++ ++ ++ GVY+CT N G +
Sbjct: 624 GHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQNSAGS-IS 682
Query: 251 TEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
L VL P + V G L C +PP ++W++ PLS +ER ++
Sbjct: 683 ANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLT 742
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRP 352
N L++ +V ED G Y+C N+LG R H ++S P
Sbjct: 743 P--DNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVLP 782
Score = 47.6 bits (108), Expect = 1e-04
Identities = 33/120 (27%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCT 283
L L ++ H G Y C + N G + +L V P T + A L C
Sbjct: 562 LHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPSFTKTPHDITIRTTTVARLECA 621
Query: 284 VLADPPAEVSWYQNS---FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
P +++W ++ FP + R M + I DV+ +D G YSC A NS G
Sbjct: 622 ATGHPNPQIAWQKDGGTDFPAARERR--MHVMPDDDVFFITDVKIDDAGVYSCTAQNSAG 679
>X16841-1|CAA34739.1| 761|Homo sapiens protein ( Human mRNA for a
nontransmembrane isoform of N-CAM from skeletal muscle.
).
Length = 761
Score = 85.0 bits (201), Expect = 5e-16
Identities = 88/354 (24%), Positives = 148/354 (41%), Gaps = 37/354 (10%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D +Y+C I++ A +Q T+ + V + + L C A+G+P+P++
Sbjct: 281 DEAEYIC-IAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSI 339
Query: 207 TWH---RLNDSSSRLGEG----------PQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
TW R S + +G L L ++ G Y CT N +G + +
Sbjct: 340 TWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMY 399
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS--FPLSASERVTMSA 311
L+V Y P++ + V+T EG + + C V A P A +SW+++ P S + +
Sbjct: 400 -LEVQYAPKLQGPVA-VYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYN 457
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARA-PHSYT 370
S L + DFGNY+C A N +G+ + P +SP + + P+S T
Sbjct: 458 TPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTP---SSPSIDQVEPYSST 514
Query: 371 LSFAVDSYPPLDELRLL-YRQ--LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRG 427
D + +L Y+ A+ E +W+D A + +G +T + G
Sbjct: 515 AQVQFDEPEATGGVPILKYKAEWRAVGEEVWH-SKWYDAKEA--SMEGIVT------IVG 565
Query: 428 LQPAAVYEAIVQAKNRYGWNEVSDIFQFHTL---GGPHTAHADELTPMFSAAPE 478
L+P Y + A N G E+S +F T P A A TP+ + P+
Sbjct: 566 LKPETTYAVRLAALNGKGLGEISAASEFKTQPVHSPPPPASASSSTPVPLSPPD 619
Score = 69.3 bits (162), Expect = 3e-11
Identities = 51/213 (23%), Positives = 94/213 (44%), Gaps = 20/213 (9%)
Query: 147 DAGDYVCQISDRVARDQVH----TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNP 202
D G Y C+ +AR +++ V V VPP+++A + TA G + L C A G P
Sbjct: 183 DEGTYRCE-GRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFP 241
Query: 203 VPTVTWHRLNDSSSR---------LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
PT++W + + + + QL + +++++ Y C +N G T
Sbjct: 242 EPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDAT-I 300
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASER-----VT 308
L+V P+IT + + L C DP ++W ++ +S+ E+ +
Sbjct: 301 HLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMV 360
Query: 309 MSARGSNHTLLIADVQPEDFGNYSCVADNSLGR 341
+ + +L + +Q D G Y C A N++G+
Sbjct: 361 VRSHARVSSLTLKSIQYTDAGEYICTASNTIGQ 393
Score = 46.8 bits (106), Expect = 2e-04
Identities = 52/227 (22%), Positives = 84/227 (37%), Gaps = 13/227 (5%)
Query: 139 TNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRA 198
T + DAG Y C ++ + TV V + + R G AV+ C
Sbjct: 82 TIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDV 141
Query: 199 AGNPVPTVTW-HRLNDSSSR------LGEGPQLQLSRLERHHGGVYACTVD-NGVGPPVV 250
+ PT+ W H+ D + + LQ+ +++ G Y C G
Sbjct: 142 VSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINF 201
Query: 251 TEFQLQVLYPPEITVERSWVH--TGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVT 308
+ Q+ V PP I ++ V+ G LVC P +SW ++ + E
Sbjct: 202 KDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDE 261
Query: 309 MSARGSNHT-LLIADVQPEDFGNYSCVADNSLGR--ARRHVEVSGRP 352
+ + L I V D Y C+A+N G A H++V +P
Sbjct: 262 KYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKP 308
Score = 33.9 bits (74), Expect = 1.3
Identities = 30/134 (22%), Positives = 56/134 (41%), Gaps = 14/134 (10%)
Query: 145 FQDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
+ DAG+Y+C S+ + +D Q +EV P ++ V G + C P
Sbjct: 377 YTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVA---VYTWEGNQVNITCEVFAYPS 433
Query: 204 PTVTWHR-------LNDSSSRLGEGPQ---LQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
T++W R N S+ ++ P L+++ + G Y CT N +G +
Sbjct: 434 ATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFI 493
Query: 254 QLQVLYPPEITVER 267
+Q P ++++
Sbjct: 494 LVQADTPSSPSIDQ 507
>BC036771-1|AAH36771.1| 226|Homo sapiens NEGR1 protein protein.
Length = 226
Score = 85.0 bits (201), Expect = 5e-16
Identities = 52/179 (29%), Positives = 81/179 (45%), Gaps = 5/179 (2%)
Query: 163 QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGP 222
QVH + V VPP + + +T G L C A G P P+++W ++ S+ G
Sbjct: 2 QVH-LTVQVPPKIYDI--SNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFENGQ 58
Query: 223 QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVC 282
L + + R G Y C+ +N V P V + ++ V + P I +S T G + C
Sbjct: 59 YLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVT-PGRSGLIRC 117
Query: 283 TVLADPPAEVSWYQNSFPL-SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
PP WY+ L + + + + + L + +V E FGNY+CVA N LG
Sbjct: 118 EGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 176
Score = 39.5 bits (88), Expect = 0.027
Identities = 45/176 (25%), Positives = 75/176 (42%), Gaps = 28/176 (15%)
Query: 91 VGPQIRYTVDVTIYENSETSVALAILGATGHTNVWETTRRIT--SEQHGNTNFRMIF--- 145
V P+I Y + + N T+V L L ATG + R I+ ++ N + I+
Sbjct: 9 VPPKI-YDISNDMTVNEGTNVTLTCL-ATGKPEPSISWRHISPSAKPFENGQYLDIYGIT 66
Query: 146 -QDAGDYVCQISDRVARDQVHTVEVLV--PPSVRASPETRHVTARRGGAAVLECRAAGNP 202
AG+Y C + V+ V V+V+V P+++ E + T G + ++ C AG P
Sbjct: 67 RDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQ---EIKSGTVTPGRSGLIRCEGAGVP 123
Query: 203 VPTVTWHRLNDSSSRLGEGPQ------------LQLSRLERHHGGVYACTVDNGVG 246
P W++ +L G Q L ++ + + H G Y C N +G
Sbjct: 124 PPAFEWYK---GEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 176
>AL627317-2|CAH72392.1| 226|Homo sapiens neuronal growth regulator
1 protein.
Length = 226
Score = 85.0 bits (201), Expect = 5e-16
Identities = 52/179 (29%), Positives = 81/179 (45%), Gaps = 5/179 (2%)
Query: 163 QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGP 222
QVH + V VPP + + +T G L C A G P P+++W ++ S+ G
Sbjct: 2 QVH-LTVQVPPKIYDI--SNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFENGQ 58
Query: 223 QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVC 282
L + + R G Y C+ +N V P V + ++ V + P I +S T G + C
Sbjct: 59 YLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVT-PGRSGLIRC 117
Query: 283 TVLADPPAEVSWYQNSFPL-SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
PP WY+ L + + + + + L + +V E FGNY+CVA N LG
Sbjct: 118 EGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 176
Score = 39.5 bits (88), Expect = 0.027
Identities = 45/176 (25%), Positives = 75/176 (42%), Gaps = 28/176 (15%)
Query: 91 VGPQIRYTVDVTIYENSETSVALAILGATGHTNVWETTRRIT--SEQHGNTNFRMIF--- 145
V P+I Y + + N T+V L L ATG + R I+ ++ N + I+
Sbjct: 9 VPPKI-YDISNDMTVNEGTNVTLTCL-ATGKPEPSISWRHISPSAKPFENGQYLDIYGIT 66
Query: 146 -QDAGDYVCQISDRVARDQVHTVEVLV--PPSVRASPETRHVTARRGGAAVLECRAAGNP 202
AG+Y C + V+ V V+V+V P+++ E + T G + ++ C AG P
Sbjct: 67 RDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQ---EIKSGTVTPGRSGLIRCEGAGVP 123
Query: 203 VPTVTWHRLNDSSSRLGEGPQ------------LQLSRLERHHGGVYACTVDNGVG 246
P W++ +L G Q L ++ + + H G Y C N +G
Sbjct: 124 PPAFEWYK---GEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 176
>AL359821-2|CAH70914.1| 226|Homo sapiens neuronal growth regulator
1 protein.
Length = 226
Score = 85.0 bits (201), Expect = 5e-16
Identities = 52/179 (29%), Positives = 81/179 (45%), Gaps = 5/179 (2%)
Query: 163 QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGP 222
QVH + V VPP + + +T G L C A G P P+++W ++ S+ G
Sbjct: 2 QVH-LTVQVPPKIYDI--SNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFENGQ 58
Query: 223 QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVC 282
L + + R G Y C+ +N V P V + ++ V + P I +S T G + C
Sbjct: 59 YLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVT-PGRSGLIRC 117
Query: 283 TVLADPPAEVSWYQNSFPL-SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
PP WY+ L + + + + + L + +V E FGNY+CVA N LG
Sbjct: 118 EGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 176
Score = 39.5 bits (88), Expect = 0.027
Identities = 45/176 (25%), Positives = 75/176 (42%), Gaps = 28/176 (15%)
Query: 91 VGPQIRYTVDVTIYENSETSVALAILGATGHTNVWETTRRIT--SEQHGNTNFRMIF--- 145
V P+I Y + + N T+V L L ATG + R I+ ++ N + I+
Sbjct: 9 VPPKI-YDISNDMTVNEGTNVTLTCL-ATGKPEPSISWRHISPSAKPFENGQYLDIYGIT 66
Query: 146 -QDAGDYVCQISDRVARDQVHTVEVLV--PPSVRASPETRHVTARRGGAAVLECRAAGNP 202
AG+Y C + V+ V V+V+V P+++ E + T G + ++ C AG P
Sbjct: 67 RDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQ---EIKSGTVTPGRSGLIRCEGAGVP 123
Query: 203 VPTVTWHRLNDSSSRLGEGPQ------------LQLSRLERHHGGVYACTVDNGVG 246
P W++ +L G Q L ++ + + H G Y C N +G
Sbjct: 124 PPAFEWYK---GEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 176
>AL356600-2|CAI23493.1| 226|Homo sapiens neuronal growth regulator
1 protein.
Length = 226
Score = 85.0 bits (201), Expect = 5e-16
Identities = 52/179 (29%), Positives = 81/179 (45%), Gaps = 5/179 (2%)
Query: 163 QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGP 222
QVH + V VPP + + +T G L C A G P P+++W ++ S+ G
Sbjct: 2 QVH-LTVQVPPKIYDI--SNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFENGQ 58
Query: 223 QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVC 282
L + + R G Y C+ +N V P V + ++ V + P I +S T G + C
Sbjct: 59 YLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVT-PGRSGLIRC 117
Query: 283 TVLADPPAEVSWYQNSFPL-SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
PP WY+ L + + + + + L + +V E FGNY+CVA N LG
Sbjct: 118 EGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 176
Score = 39.5 bits (88), Expect = 0.027
Identities = 45/176 (25%), Positives = 75/176 (42%), Gaps = 28/176 (15%)
Query: 91 VGPQIRYTVDVTIYENSETSVALAILGATGHTNVWETTRRIT--SEQHGNTNFRMIF--- 145
V P+I Y + + N T+V L L ATG + R I+ ++ N + I+
Sbjct: 9 VPPKI-YDISNDMTVNEGTNVTLTCL-ATGKPEPSISWRHISPSAKPFENGQYLDIYGIT 66
Query: 146 -QDAGDYVCQISDRVARDQVHTVEVLV--PPSVRASPETRHVTARRGGAAVLECRAAGNP 202
AG+Y C + V+ V V+V+V P+++ E + T G + ++ C AG P
Sbjct: 67 RDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQ---EIKSGTVTPGRSGLIRCEGAGVP 123
Query: 203 VPTVTWHRLNDSSSRLGEGPQ------------LQLSRLERHHGGVYACTVDNGVG 246
P W++ +L G Q L ++ + + H G Y C N +G
Sbjct: 124 PPAFEWYK---GEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 176
>AL354949-2|CAI16870.1| 226|Homo sapiens neuronal growth regulator
1 protein.
Length = 226
Score = 85.0 bits (201), Expect = 5e-16
Identities = 52/179 (29%), Positives = 81/179 (45%), Gaps = 5/179 (2%)
Query: 163 QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGP 222
QVH + V VPP + + +T G L C A G P P+++W ++ S+ G
Sbjct: 2 QVH-LTVQVPPKIYDI--SNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFENGQ 58
Query: 223 QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVC 282
L + + R G Y C+ +N V P V + ++ V + P I +S T G + C
Sbjct: 59 YLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVT-PGRSGLIRC 117
Query: 283 TVLADPPAEVSWYQNSFPL-SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
PP WY+ L + + + + + L + +V E FGNY+CVA N LG
Sbjct: 118 EGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 176
Score = 39.5 bits (88), Expect = 0.027
Identities = 45/176 (25%), Positives = 75/176 (42%), Gaps = 28/176 (15%)
Query: 91 VGPQIRYTVDVTIYENSETSVALAILGATGHTNVWETTRRIT--SEQHGNTNFRMIF--- 145
V P+I Y + + N T+V L L ATG + R I+ ++ N + I+
Sbjct: 9 VPPKI-YDISNDMTVNEGTNVTLTCL-ATGKPEPSISWRHISPSAKPFENGQYLDIYGIT 66
Query: 146 -QDAGDYVCQISDRVARDQVHTVEVLV--PPSVRASPETRHVTARRGGAAVLECRAAGNP 202
AG+Y C + V+ V V+V+V P+++ E + T G + ++ C AG P
Sbjct: 67 RDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQ---EIKSGTVTPGRSGLIRCEGAGVP 123
Query: 203 VPTVTWHRLNDSSSRLGEGPQ------------LQLSRLERHHGGVYACTVDNGVG 246
P W++ +L G Q L ++ + + H G Y C N +G
Sbjct: 124 PPAFEWYK---GEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 176
>AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein
LIG-1 protein.
Length = 1094
Score = 85.0 bits (201), Expect = 5e-16
Identities = 59/222 (26%), Positives = 94/222 (42%), Gaps = 16/222 (7%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTVEVLVP--PSVRASPETRHVTARRGGAAVLECRAA 199
++ F G Y C I++ H + V PS +P +T R A LEC A
Sbjct: 566 QVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPSFTKTPHD--ITIRTTTMARLECAAT 623
Query: 200 GNPVPTVTWHRLNDSSSRLGEGPQLQ---------LSRLERHHGGVYACTVDNGVGPPVV 250
G+P P + W + + ++ ++ ++ GVY+CT N G +
Sbjct: 624 GHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQNSAGS-IS 682
Query: 251 TEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
L VL P + V G L C +PP ++W++ PLS +ER ++
Sbjct: 683 ANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLT 742
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRP 352
N L++ +V ED G Y+C N+LG R H ++S P
Sbjct: 743 P--DNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVLP 782
Score = 48.4 bits (110), Expect = 6e-05
Identities = 33/120 (27%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCT 283
L L ++ H G Y C + N G + +L V P T + A L C
Sbjct: 562 LHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPSFTKTPHDITIRTTTMARLECA 621
Query: 284 VLADPPAEVSWYQNS---FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
P +++W ++ FP + R M + I DV+ +D G YSC A NS G
Sbjct: 622 ATGHPNPQIAWQKDGGTDFPAARERR--MHVMPDDDVFFITDVKIDDAGVYSCTAQNSAG 679
>X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein.
Length = 7962
Score = 82.6 bits (195), Expect = 3e-15
Identities = 59/218 (27%), Positives = 91/218 (41%), Gaps = 11/218 (5%)
Query: 147 DAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D+G Y+CQ+S+ V T+ V PP P V R G + EC+ G P
Sbjct: 1499 DSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVL-RNGQSTTFECQITGTPKIR 1557
Query: 206 VTWHRLNDSSSRLGEG--------PQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V+W+ + + + + Q+S + G Y C N G + +L+V
Sbjct: 1558 VSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCS-IELKV 1616
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP E V + EL C V PP EV+W +N+ + +S++ T++ R S
Sbjct: 1617 KEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFN 1676
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L I P D G Y C+ N G V+ + P+
Sbjct: 1677 LHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPS 1714
Score = 82.2 bits (194), Expect = 4e-15
Identities = 72/263 (27%), Positives = 111/263 (42%), Gaps = 17/263 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D+G Y CQ ++ V +D + V PP E V A++G + LEC+ +G+P
Sbjct: 3002 DSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKV-AKQGESIQLECKISGSPEIK 3060
Query: 206 VTWHRLNDSS---------SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
V+W R NDS S + L ++ G Y C NGVG + L
Sbjct: 3061 VSWFR-NDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCST-ALT 3118
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
V PP T + S V +G L C + PP EV W ++ + S++ ++++ +
Sbjct: 3119 VKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDT 3178
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFT---SPPLARAPHSYTLSF 373
L I +++ D G Y C A N +G V + P RF S + L
Sbjct: 3179 NLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKE-PPRFVKKLSDTSTLIGDAVELRA 3237
Query: 374 AVDSYPPLDELRLLYRQLAINES 396
V+ + P+ + L R I ES
Sbjct: 3238 IVEGFQPISVVWLKDRGEVIRES 3260
Score = 77.4 bits (182), Expect = 1e-13
Identities = 59/226 (26%), Positives = 96/226 (42%), Gaps = 15/226 (6%)
Query: 147 DAGDYVCQI-SDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+AG Y CQI +D ++ T+ VL P ++ PE+ VT G LEC AG P +
Sbjct: 4224 NAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTT--GDTCTLECTVAGTPELS 4281
Query: 206 VTWHR-----LNDSSSRLG---EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
W + +D+ ++ + L++ + GVY+ V N VG T LQV
Sbjct: 4282 TKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTA-SLQV 4340
Query: 258 ---LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
PP T + + G + C V PP VSW+ +S+ + + +
Sbjct: 4341 SDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDN 4400
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
L + ++ D G+Y+C+A N G ++ R P+ P
Sbjct: 4401 TCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKP 4446
Score = 76.2 bits (179), Expect = 3e-13
Identities = 54/216 (25%), Positives = 94/216 (43%), Gaps = 13/216 (6%)
Query: 137 GNTNFRMIFQ-DA---GDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAA 192
G+T+F ++ DA G Y C +++ V D T+ ++ P + G ++
Sbjct: 2047 GSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSS 2106
Query: 193 VLECRAAGNPVPTVTW----HRLNDSSSR----LGEGPQLQLSRLERHHGGVYACTVDNG 244
LEC+ AG+P V W H L S + +Q++ L G + C N
Sbjct: 2107 RLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNP 2166
Query: 245 VGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
G + ++ V PP + V T + L C + PP EV WY++ L +S
Sbjct: 2167 AGSTSCST-KVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSS 2225
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
++ ++++ + ++ I +V D G Y C A N +G
Sbjct: 2226 KKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVG 2261
Score = 75.8 bits (178), Expect = 3e-13
Identities = 59/218 (27%), Positives = 88/218 (40%), Gaps = 15/218 (6%)
Query: 146 QDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C+I + RD V L PP E + A G + L+C+ AG P
Sbjct: 2716 RDAGQYSCEIENEAGRDVCGALVSTLEPPYFVT--ELEPLEAAVGDSVSLQCQVAGTPEI 2773
Query: 205 TVTWHRLNDSSSR---------LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVV-TEFQ 254
TV+W++ D+ R L +++ + G Y C +N +G T F+
Sbjct: 2774 TVSWYK-GDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFR 2832
Query: 255 LQVLY-PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
+Q PP + + G L C + P +V WY++ L E + S
Sbjct: 2833 IQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDHENLQTSFVD 2892
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR 351
+ TL I G YSC A N LG A ++ R
Sbjct: 2893 NVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAR 2930
Score = 72.9 bits (171), Expect = 2e-12
Identities = 60/210 (28%), Positives = 87/210 (41%), Gaps = 17/210 (8%)
Query: 146 QDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C I + +D + +L PP E V+ G +A L+C+ AG P
Sbjct: 4598 EDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSV--GDSASLQCQLAGTPEI 4655
Query: 205 TVTWHRLNDSSSR---------LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF-- 253
V+W++ D+ R L ++++ + G Y C +N VG + F
Sbjct: 4656 GVSWYK-GDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLT 4714
Query: 254 -QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
Q Q L PP + + V G C + P VSWY++ PL S V S
Sbjct: 4715 VQEQKL-PPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFL 4773
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+ TL I G YSC A N +G A
Sbjct: 4774 DNTATLNIFKTDRSLAGQYSCTATNPIGSA 4803
Score = 72.9 bits (171), Expect = 2e-12
Identities = 61/224 (27%), Positives = 93/224 (41%), Gaps = 17/224 (7%)
Query: 147 DAGDYVCQISDRVARD----QVHTVEVLVPPS-VRASPETRHVTARRGGAAVLECRAAGN 201
D+G Y C + V +D Q++ E L+PPS + ET V G + LE R AG+
Sbjct: 4884 DSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSET--VEETEGNSFKLEGRVAGS 4941
Query: 202 PVPTVTWHRLN-----DSSSRL---GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
TV W++ N S+ + LQ+ + + G+Y C V N G + T
Sbjct: 4942 QPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSS 5001
Query: 254 QL--QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA 311
+ + PP + V EG +L C V P + W + + S+R + S
Sbjct: 5002 IVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSF 5061
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L + DV D G+Y C A N G +V+ + PA
Sbjct: 5062 ASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPA 5105
Score = 71.3 bits (167), Expect = 7e-12
Identities = 53/205 (25%), Positives = 86/205 (41%), Gaps = 11/205 (5%)
Query: 146 QDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D+G YVC S+ TV V PPS + ++ G +A L C+ G+PV
Sbjct: 374 KDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLP-GESARLHCKLKGSPVI 432
Query: 205 TVTWHRLNDSSSR--------LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
VTW + N S + L ++ ++ G Y+C N VG + ++
Sbjct: 433 QVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCST-EIV 491
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
+ PP G A L C V P E+SW+++ + +S++ + ++ S
Sbjct: 492 IKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLV 551
Query: 317 TLLIADVQPEDFGNYSCVADNSLGR 341
L I D G Y CV N +G+
Sbjct: 552 CLEIFSFNSADVGEYECVVANEVGK 576
Score = 71.3 bits (167), Expect = 7e-12
Identities = 53/183 (28%), Positives = 81/183 (44%), Gaps = 13/183 (7%)
Query: 189 GGAAVLECRAAGNPVPTVTWHRLND--------SSSRLGEGPQLQLSRLERHHGGVYACT 240
G +A EC G +TW + N + + +G P L++ ++ + G Y C
Sbjct: 2950 GESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQ 3009
Query: 241 VDNGVGPPVVTEFQLQVLYPPEIT--VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS 298
N VG + + QL V PP+ +E S V +G +L C + P +VSW++N
Sbjct: 3010 ATNDVGKDMCSA-QLSVKEPPKFVKKLEASKV-AKQGESIQLECKISGSPEIKVSWFRND 3067
Query: 299 FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFT 358
L S + MS S L I + ED G+Y C A N +G A ++ + P FT
Sbjct: 3068 SELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPV-FT 3126
Query: 359 SPP 361
P
Sbjct: 3127 QKP 3129
Score = 71.3 bits (167), Expect = 7e-12
Identities = 58/209 (27%), Positives = 88/209 (42%), Gaps = 17/209 (8%)
Query: 147 DAGDYVCQISDRVARDQ----VHTVEVLVPPS-VRASPETRHVTARRGGAAVLECRAAGN 201
D+G Y ++ + V +D + + VPPS R ET ++ G + V+EC+ G+
Sbjct: 4317 DSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLS---GSSVVMECKVYGS 4373
Query: 202 PVPTVTW-HRLNDSSS------RLGEGP-QLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
P +V+W H N+ SS L + L ++ LE G Y C N G +
Sbjct: 4374 PPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSA- 4432
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
L V PP + + G V PP VSW++ S L +R +S
Sbjct: 4433 PLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLED 4492
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRA 342
S L + DV G Y+C+ N G+A
Sbjct: 4493 SVAELELFDVDTSQSGEYTCIVSNEAGKA 4521
Score = 70.9 bits (166), Expect = 1e-11
Identities = 58/208 (27%), Positives = 84/208 (40%), Gaps = 15/208 (7%)
Query: 147 DAGDYVCQISDRVARDQ----VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNP 202
D G Y ++ + V + VH + +VPPS + + V A G + VLECR +G+
Sbjct: 3376 DKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIR--KLKDVNAILGASVVLECRVSGSA 3433
Query: 203 VPTVTWHRLNDS-------SSRLGEGP-QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
+V W + + S E L LS LE G+Y C N G +
Sbjct: 3434 PISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAV- 3492
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
L V PP V G + PP +V W++ S L E +S
Sbjct: 3493 LTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDF 3552
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRA 342
L + +VQP + G+YSC+ N G A
Sbjct: 3553 VTELELFEVQPLESGDYSCLVTNDAGSA 3580
Score = 70.1 bits (164), Expect = 2e-11
Identities = 54/211 (25%), Positives = 84/211 (39%), Gaps = 19/211 (9%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+D Y C I + +D + ++ P P HV A G A L+C+ G P
Sbjct: 3657 EDYAQYSCLIENEAGQDICEALVSVLEPPYFIEP-LEHVEAVIGEPATLQCKVDGTPEIR 3715
Query: 206 VTWHRLNDSSSRLGEGP-----------QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
++W++ ++L P L +++++ G Y+C DN VG V +
Sbjct: 3716 ISWYK---EHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGA-VASSAV 3771
Query: 255 LQVL---YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA 311
L + PP + VH GF C + P +VSWY++ L + S
Sbjct: 3772 LVIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSF 3831
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+ TL I G Y+C A N LG A
Sbjct: 3832 VHNVATLQILQTDQSHIGQYNCSASNPLGTA 3862
Score = 70.1 bits (164), Expect = 2e-11
Identities = 50/201 (24%), Positives = 82/201 (40%), Gaps = 10/201 (4%)
Query: 148 AGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
+G+Y C +S+ + T + + + + +G +LE G P +VT
Sbjct: 4507 SGEYTCIVSNEAGKASC-TTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVT 4565
Query: 208 WHR--LNDSSSR------LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
W + +N + S+ + P L++ G Y C ++N G + Q+ +L
Sbjct: 4566 WKKNGINVTPSQRCNITTTEKSPILEIPSSTVEDAGQYNCYIENASGKDSCSA-QILILE 4624
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
PP + V G A L C + P VSWY+ L + M R + TL+
Sbjct: 4625 PPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLV 4684
Query: 320 IADVQPEDFGNYSCVADNSLG 340
V D G Y C A+NS+G
Sbjct: 4685 FNQVDINDSGEYICKAENSVG 4705
Score = 68.5 bits (160), Expect = 5e-11
Identities = 58/210 (27%), Positives = 87/210 (41%), Gaps = 15/210 (7%)
Query: 142 RMIFQDAGDYVCQISDRV-ARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
R+ DAG++ C+ ++ V ++D + V PPS P ++ V G A L+ G
Sbjct: 839 RVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLP--GSAVCLKSTFQG 896
Query: 201 NPVPTVTWHRLNDSSSRLGE--------GPQLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
+ T+ W + N G L+L ++ G Y C V N G V
Sbjct: 897 STPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGG-VECS 955
Query: 253 FQLQVLYPPEIT--VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
L V P +E S + +G +L C V PP +++W+ N + S + MS
Sbjct: 956 ANLFVKEPATFVEKLEPSQL-LKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMS 1014
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
S L + DV ED G Y C A N G
Sbjct: 1015 FVESTAVLRLTDVGIEDSGEYMCEAQNEAG 1044
Score = 68.5 bits (160), Expect = 5e-11
Identities = 51/203 (25%), Positives = 83/203 (40%), Gaps = 11/203 (5%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
DAG Y C S+ +D + V PP E + ++ EC+ G+P
Sbjct: 3943 DAGQYTCYASNIAGKDSCSAQLGVQEPPRFIKKLEPSRIV-KQDEFTRYECKIGGSPEIK 4001
Query: 206 VTWHR----LNDSS----SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V W++ + +SS S + L++ L G Y C N G + L+V
Sbjct: 4002 VLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGS-ASSSTSLKV 4060
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP + + T +G L C + PP VSWY++ L + ++ + + +
Sbjct: 4061 KEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTS 4120
Query: 318 LLIADVQPEDFGNYSCVADNSLG 340
+ I +V D G Y C A N +G
Sbjct: 4121 IHILNVDAADIGEYQCKATNDVG 4143
Score = 68.5 bits (160), Expect = 5e-11
Identities = 58/228 (25%), Positives = 99/228 (43%), Gaps = 18/228 (7%)
Query: 147 DAGDYVCQISDRVARDQVHTV----EVLVPPSVRASPETRHVTARRGGAAVLECRAAGNP 202
D+G+Y+C+ + V T E +PPS S + R V G V +C +G+
Sbjct: 4692 DSGEYICKAENSVGEVSASTFLTVQEQKLPPSF--SRQLRDVQETVGLPVVFDCAISGSE 4749
Query: 203 VPTVTWHR----LNDS----SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
+V+W++ L DS +S L L + + +R G Y+CT N +G +
Sbjct: 4750 PISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARL 4809
Query: 255 L--QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
+ + PP + + V G A+ C V P +VSW ++S + + + +S
Sbjct: 4810 ILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYL 4869
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGR--ARRHVEVSGRPGPARFT 358
++ L + V D G Y+C A N +G+ + + R P FT
Sbjct: 4870 ENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT 4917
Score = 66.9 bits (156), Expect = 2e-10
Identities = 60/226 (26%), Positives = 93/226 (41%), Gaps = 19/226 (8%)
Query: 143 MIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNP 202
+ QD G Y C+ S++ D + E+++ E V + LEC+ +
Sbjct: 278 LTIQDRGVYSCKASNKFGAD-ICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDR 336
Query: 203 VPTVTWHRLNDSSSRLGEGPQ-----------LQLSRLERHHGGVYACTVDNGVGPPVVT 251
TVTW + +L G L++ + G Y CT N G +
Sbjct: 337 KVTVTWSK---DGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCS 393
Query: 252 EFQLQVLYPPEIT--VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTM 309
+ V PP V+ S++ G A L C + P +V+W++N+ LS S V M
Sbjct: 394 A-TVTVREPPSFVKKVDPSYLML-PGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRM 451
Query: 310 SARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
S L I DV+ ED G+YSC A N +G E+ + P+
Sbjct: 452 YFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPS 497
Score = 65.7 bits (153), Expect = 4e-10
Identities = 52/202 (25%), Positives = 79/202 (39%), Gaps = 10/202 (4%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
++GDY C +++ T + V + G VLE G P +V
Sbjct: 3565 ESGDYSCLVTNDAGSASC-TTHLFVKEPATFVKRLADFSVETGSPIVLEATYTGTPPISV 3623
Query: 207 TWHR---LNDSSSRLG-----EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+W + L S R + L++ Y+C ++N G + E + VL
Sbjct: 3624 SWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDIC-EALVSVL 3682
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP V G A L C V P +SWY+ L ++ M + + +L
Sbjct: 3683 EPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASL 3742
Query: 319 LIADVQPEDFGNYSCVADNSLG 340
+I V D G YSC ADNS+G
Sbjct: 3743 VINKVDHSDVGEYSCKADNSVG 3764
Score = 63.7 bits (148), Expect = 1e-09
Identities = 57/220 (25%), Positives = 90/220 (40%), Gaps = 14/220 (6%)
Query: 147 DAGDYVCQISDR---VARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D G+Y C+ S+ V+ TV PP+ + P++ +T G AA C G PV
Sbjct: 187 DCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKS--LTTFVGKAAKFICTVTGTPV 244
Query: 204 PTVTWHR----LNDSSS-RLGEGPQ---LQLSRLERHHGGVYACTVDNGVGPPVVTEFQL 255
W + L+ S + R+ + L+LS L GVY+C N G + + +L
Sbjct: 245 IETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADIC-QAEL 303
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
++ P E V + + L C V D V+W ++ L + +
Sbjct: 304 IIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKI 363
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
TL I + +D G Y C A N G + V+ R P+
Sbjct: 364 ATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPS 403
Score = 63.7 bits (148), Expect = 1e-09
Identities = 61/226 (26%), Positives = 95/226 (42%), Gaps = 19/226 (8%)
Query: 147 DAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G+Y C+ + V D V TV++ PP R + +T G A L+ G
Sbjct: 2248 DIGEYHCKAQNEVGSDTCVCTVKLKEPP--RFVSKLNSLTVVAGEPAELQASIEGAQPIF 2305
Query: 206 VTWHRLNDSSSRLGEGPQ---------LQLSRLERHHGGVYACTV--DNGVGPPVVTEFQ 254
V W + + R E + LQ ++ E + G Y C + D G+ + T
Sbjct: 2306 VQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMAT--- 2362
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
L VL P I + + G L C V P V WY++ L++S++ S
Sbjct: 2363 LMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNK 2422
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRA--RRHVEVSGRPGPARFT 358
+L I V+ +D G Y+ N++G++ V+VS R P FT
Sbjct: 2423 ISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFT 2468
Score = 63.7 bits (148), Expect = 1e-09
Identities = 50/210 (23%), Positives = 82/210 (39%), Gaps = 10/210 (4%)
Query: 141 FRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
F + +G+Y C +S+ + T + P+ + H + G + +LE G
Sbjct: 2618 FNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDH-SVEPGKSIILESTYTG 2676
Query: 201 NPVPTVTWHR--LNDSSSR------LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
+VTW + N ++S + L++ + G Y+C ++N G V
Sbjct: 2677 TLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGA 2736
Query: 253 FQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
+ L PP E + G L C V P VSWY+ L +
Sbjct: 2737 L-VSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFT 2795
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+ TL+ V D G Y+C A+NS+G A
Sbjct: 2796 NNVATLVFNKVNINDSGEYTCKAENSIGTA 2825
Score = 62.1 bits (144), Expect = 4e-09
Identities = 56/224 (25%), Positives = 87/224 (38%), Gaps = 15/224 (6%)
Query: 147 DAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G+Y C+ ++ V D V ++ + PP R + ++ G L+ G +
Sbjct: 4130 DIGEYQCKATNDVGSDTCVGSIALKAPP--RFVKKLSDISTVVGKEVQLQTTIEGAEPIS 4187
Query: 206 VTWHRLNDSSSRLGEG---------PQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
V W + R + LQ SR+E + G Y C + N G L
Sbjct: 4188 VVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFA-TLS 4246
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
VL P I + + G L CTV P W+++ L++ + +S
Sbjct: 4247 VLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVS 4306
Query: 317 TLLIADVQPEDFGNYSCVADNSLGR--ARRHVEVSGRPGPARFT 358
L I +V P D G YS N +G+ ++VS R P FT
Sbjct: 4307 GLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFT 4350
Score = 61.7 bits (143), Expect = 6e-09
Identities = 52/210 (24%), Positives = 84/210 (40%), Gaps = 12/210 (5%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
+ + DAG+Y C++++ V V + PPS E+ ++ RGG A + G
Sbjct: 1119 KFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIES--TSSLRGGTAAFQATLKG 1176
Query: 201 NPVPTVTWHR-----LNDSSSRL---GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
+ TVTW + D + R+ L LS +E H G Y C N G +
Sbjct: 1177 SLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSA 1236
Query: 253 FQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
L V P IT E + +G A L W+++ L+ + +S
Sbjct: 1237 L-LSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVT 1295
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+ L I + +D G Y+ N +GR+
Sbjct: 1296 DTVSILKIISTEKKDSGEYTFEVQNDVGRS 1325
Score = 60.1 bits (139), Expect = 2e-08
Identities = 50/212 (23%), Positives = 84/212 (39%), Gaps = 21/212 (9%)
Query: 146 QDAGDYVCQISDRVARDQVHTV----EVLVPPSVRASPETRHVTARRGGAAVLECRAAGN 201
QDAG Y Q+ + V + V + VPPS + ++ G + +LEC+ AG+
Sbjct: 2434 QDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSF--TRRLKNTGGVLGASCILECKVAGS 2491
Query: 202 PVPTVTWHRLNDSSSRLGEGPQ-----------LQLSRLERHHGGVYACTVDNGVGPPVV 250
+V W +++ G + LQL+ L+ G Y C N G
Sbjct: 2492 SPISVAWFH---EKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDEC 2548
Query: 251 TEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
L V PP E + G + PP +V+W++ + L +R +
Sbjct: 2549 RAV-LTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIY 2607
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+ L + ++ G Y+CV N+ G+A
Sbjct: 2608 FEDTVAELELFNIDISQSGEYTCVVSNNAGQA 2639
Score = 59.7 bits (138), Expect = 2e-08
Identities = 56/228 (24%), Positives = 91/228 (39%), Gaps = 15/228 (6%)
Query: 146 QDAGDYVCQISDRVARDQVHTV-EVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D +Y C++S+ D + V PPS P + A + G P
Sbjct: 1967 EDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQ--AIPDSTVEFKAILKGTPPF 2024
Query: 205 TVTWHR-----LNDSSSRLG-EGPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
+ W + ++ +G EG L L ++ G Y C V N VG T L
Sbjct: 2025 KIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLL- 2083
Query: 257 VLYPPEIT--VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP+ +E S + G + L C + P V W++N L AS++ M+ S
Sbjct: 2084 VTEPPKFVKKLEASKI-VKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDS 2142
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPL 362
+ + ++ ED G++ C A N G +V + P + PP+
Sbjct: 2143 VAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPI 2190
Score = 58.4 bits (135), Expect = 5e-08
Identities = 45/206 (21%), Positives = 87/206 (42%), Gaps = 10/206 (4%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+D+G+Y+C+ + D ++ V+V S + E + + + +L AG P
Sbjct: 1030 EDSGEYMCEAQNEAGSDHCSSI-VIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFE 1088
Query: 206 VTWHRLND---SSSRLGEGPQ-----LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+TW + N S + Q LQ+ + G Y C V N VG + + ++ +
Sbjct: 1089 ITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSA-RVTL 1147
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP + + G A T+ P V+W ++S ++ + + M+ + +
Sbjct: 1148 REPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVAS 1207
Query: 318 LLIADVQPEDFGNYSCVADNSLGRAR 343
L ++ ++ + G Y C A N G R
Sbjct: 1208 LYLSGIEVKHDGKYVCQAKNDAGIQR 1233
Score = 58.0 bits (134), Expect = 7e-08
Identities = 47/203 (23%), Positives = 82/203 (40%), Gaps = 13/203 (6%)
Query: 149 GDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW 208
G YVCQ + + + + P+ + E + +G A L+ + +G T W
Sbjct: 1219 GKYVCQAKNDAGIQRCSALLSVKEPAT-ITEEAVSIDVTQGDPATLQVKFSGTKEITAKW 1277
Query: 209 HRLNDSSSRLGEGPQ---------LQLSRLERHHGGVYACTVDNGVGPPVVTEF--QLQV 257
+ + LG + L++ E+ G Y V N VG L +
Sbjct: 1278 FK-DGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDL 1336
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
+ PP T + + + +G +L C V P + W+++ +SASE+ S +
Sbjct: 1337 IIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAF 1396
Query: 318 LLIADVQPEDFGNYSCVADNSLG 340
L I+ ++ D G Y+C A N G
Sbjct: 1397 LEISQLEGTDSGTYTCSATNKAG 1419
Score = 57.6 bits (133), Expect = 9e-08
Identities = 52/204 (25%), Positives = 82/204 (40%), Gaps = 12/204 (5%)
Query: 147 DAGDYVCQISDRVARDQVHTV-EVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C ++ D+ V V PPS +P++ V G + G P
Sbjct: 3472 DTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLP--GMSLTFTSVIRGTPPFK 3529
Query: 206 VTWHRLN------DSSSRLGEG--PQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V W + + +S + E +L+L ++ G Y+C V N G T L V
Sbjct: 3530 VKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTT-HLFV 3588
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
P + G L T PP VSW ++ + +S SER +++ +
Sbjct: 3589 KEPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTI 3648
Query: 318 LLIADVQPEDFGNYSCVADNSLGR 341
L I + ED+ YSC+ +N G+
Sbjct: 3649 LEILESTIEDYAQYSCLIENEAGQ 3672
Score = 57.6 bits (133), Expect = 9e-08
Identities = 51/207 (24%), Positives = 80/207 (38%), Gaps = 18/207 (8%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D+GDY C ++ D+ + V PPS P+ V G G P +
Sbjct: 4413 DSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLT--GTNVTFTSIVKGTPPFS 4470
Query: 206 VTWHRLNDSSSRLGEGP-----------QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
V+W + SS L G +L+L ++ G Y C V N G T
Sbjct: 4471 VSWFK---GSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTT-H 4526
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
L + P + + +G L T PP V+W +N ++ S+R ++
Sbjct: 4527 LYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEK 4586
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGR 341
+ L I ED G Y+C +N+ G+
Sbjct: 4587 SPILEIPSSTVEDAGQYNCYIENASGK 4613
Score = 56.0 bits (129), Expect = 3e-07
Identities = 51/202 (25%), Positives = 78/202 (38%), Gaps = 11/202 (5%)
Query: 149 GDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW 208
G Y C +++ A Q E++V + + G A LE AG P W
Sbjct: 657 GKYTC-LAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKW 715
Query: 209 HR-----LNDSSSRLG---EGPQLQLSRLERHHGGVYACTVDNGVGPPVV-TEFQ-LQVL 258
++ + R+ QL+ E H G Y + N VG T F L
Sbjct: 716 YKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRD 775
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
P T V + L C + P VSW+++ ++AS+R ++ +L
Sbjct: 776 IAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASL 835
Query: 319 LIADVQPEDFGNYSCVADNSLG 340
I V D GN++C A NS+G
Sbjct: 836 EIIRVDMNDAGNFTCRATNSVG 857
Score = 55.2 bits (127), Expect = 5e-07
Identities = 53/204 (25%), Positives = 80/204 (39%), Gaps = 12/204 (5%)
Query: 146 QDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D+G Y C+ + V D T + + PPS + E + RG A+L+C +G
Sbjct: 468 EDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIV--RGTNALLQCEVSGTGPF 525
Query: 205 TVTWHRLND---SSSRLGEGPQLQLSRLE-----RHHGGVYACTVDNGVGPPVVTEFQLQ 256
++W + SS + Q L LE G Y C V N VG L
Sbjct: 526 EISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHL- 584
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
+ PP + + G L V P V+W + + ++ MS
Sbjct: 585 LKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVA 644
Query: 317 TLLIADVQPEDFGNYSCVADNSLG 340
L+I DVQ G Y+C+A+N G
Sbjct: 645 VLIIPDVQISFGGKYTCLAENEAG 668
Score = 54.8 bits (126), Expect = 7e-07
Identities = 44/210 (20%), Positives = 91/210 (43%), Gaps = 17/210 (8%)
Query: 146 QDAGDYVCQISDRVARD----QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGN 201
+D+G+Y ++ + V R +++ +++++PPS + + + + + +G LEC AG+
Sbjct: 1309 KDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSF--TKKLKKMDSIKGSFIDLECIVAGS 1366
Query: 202 PVPTVTWHRLNDSSSRLGEGPQ---------LQLSRLERHHGGVYACTVDNGVGPPVVTE 252
++ W + +D E + L++S+LE G Y C+ N G +
Sbjct: 1367 HPISIQWFK-DDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSG 1425
Query: 253 FQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
L V PP + R +L V P + W++++ L + ++
Sbjct: 1426 -HLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKD 1484
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
++ +L + + D G Y C N +G A
Sbjct: 1485 DTSTSLELFAAKATDSGTYICQLSNDVGTA 1514
Score = 54.4 bits (125), Expect = 9e-07
Identities = 46/217 (21%), Positives = 83/217 (38%), Gaps = 9/217 (4%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+G Y C++S+ + + P+ ++G A L C+ G P +
Sbjct: 937 DSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKI 996
Query: 207 TW----HRLNDSS----SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
TW + +SS S + L+L+ + G Y C N G + + V
Sbjct: 997 TWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVI-VK 1055
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
P T E + + + L+ V PP E++W++++ L + + + +L
Sbjct: 1056 ESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSL 1115
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
I D G Y C N +G + V+ R P+
Sbjct: 1116 QILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPS 1152
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/118 (28%), Positives = 50/118 (42%), Gaps = 1/118 (0%)
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTE-FQLQVLYPPEITVERSWVHTGEGFRAELVC 282
L++ R + G Y C N G T + YPP + T G A+ +C
Sbjct: 178 LEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFIC 237
Query: 283 TVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
TV P E W ++ LS S +S + H L ++++ +D G YSC A N G
Sbjct: 238 TVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFG 295
Score = 53.6 bits (123), Expect = 2e-06
Identities = 51/205 (24%), Positives = 77/205 (37%), Gaps = 13/205 (6%)
Query: 146 QDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D+GDY+C+ + V T + V PP P V A +G +L+C +G P
Sbjct: 3095 EDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSP--VGALKGSDVILQCEISGTPPF 3152
Query: 205 TVTWHR-----LNDSSSRLGE---GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
V W + N ++ L + LE G Y C N VG + ++
Sbjct: 3153 EVVWVKDRKQVRNSKKFKITSKHFDTNLHILNLEASDVGEYHCKATNEVGSDTCS-CSVK 3211
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQN-SFPLSASERVTMSARGSN 315
PP + S T G EL V P V W ++ + SE +S +
Sbjct: 3212 FKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNI 3271
Query: 316 HTLLIADVQPEDFGNYSCVADNSLG 340
TL + + + G Y C N G
Sbjct: 3272 ATLQLGSPEASNSGKYICQIKNDAG 3296
Score = 52.8 bits (121), Expect = 3e-06
Identities = 66/245 (26%), Positives = 96/245 (39%), Gaps = 23/245 (9%)
Query: 130 RITSEQHGNTNFRMI---FQDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVT 185
+ITS+ H +TN ++ D G+Y C+ ++ V D +V+ PP R + +
Sbjct: 3170 KITSK-HFDTNLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPP--RFVKKLSDTS 3226
Query: 186 ARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQ---------LQLSRLERHHGGV 236
G A L G +V W + R E + LQL E + G
Sbjct: 3227 TLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGK 3286
Query: 237 YACTVDNGVGPPVVTEFQLQVLYPPEITV--ERSWVHTGEGFRAELVCTVLADPPAEVSW 294
Y C + N G + L VL P I E V TG F E C V P W
Sbjct: 3287 YICQIKNDAGMRECSAV-LTVLEPARIIEKPEPMTVTTGNPFALE--CVVTGTPELSAKW 3343
Query: 295 YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRAR--RHVEVSGRP 352
+++ LSA + ++ +L I + D G YS NS+G++ V VS R
Sbjct: 3344 FKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRI 3403
Query: 353 GPARF 357
P F
Sbjct: 3404 VPPSF 3408
Score = 50.4 bits (115), Expect = 1e-05
Identities = 53/210 (25%), Positives = 80/210 (38%), Gaps = 18/210 (8%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASP----ETRHVTARRGGAAVLECRAAGN 201
+++G YVC+ AR+ T + V+ P E + V + LEC G
Sbjct: 1592 ENSGTYVCE-----ARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGT 1646
Query: 202 PVPTVTWHRLND---SSSRLGEGPQ-----LQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
P VTW + N SS + + L +++ + G Y C V N G
Sbjct: 1647 PPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNE-GGSCSCST 1705
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
++ + PP + T A TV PP ++W ++ L + V +S
Sbjct: 1706 RVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVD 1765
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRAR 343
S TL I V G Y+C A N G R
Sbjct: 1766 SVATLQIRSVDNGHSGRYTCQAKNESGVER 1795
Score = 48.8 bits (111), Expect = 4e-05
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
+YPP I T EG A C V + +VSWY + S M+ +
Sbjct: 7 VYPPAIITPLQDTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQ 65
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
L IA+ PED G Y+ VA+N++G+ +S
Sbjct: 66 LEIAEAYPEDEGTYTFVANNAVGQVSSTANLS 97
Score = 48.4 bits (110), Expect = 6e-05
Identities = 43/204 (21%), Positives = 77/204 (37%), Gaps = 13/204 (6%)
Query: 148 AGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
+G Y CQ + ++ + +LV + + + V LEC AG P V
Sbjct: 1780 SGRYTCQAKNESGVERCYAF-LLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVK 1838
Query: 208 WHRLND--------SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL- 258
W + S S ++ + + G Y V+N G + L+VL
Sbjct: 1839 WLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAY-LRVLD 1897
Query: 259 --YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP T + + + G + C V P W+++ +S S + + +
Sbjct: 1898 QNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSV 1957
Query: 317 TLLIADVQPEDFGNYSCVADNSLG 340
+L + +++ ED NY+C N G
Sbjct: 1958 SLEVNNLELEDTANYTCKVSNVAG 1981
Score = 48.0 bits (109), Expect = 8e-05
Identities = 52/220 (23%), Positives = 83/220 (37%), Gaps = 18/220 (8%)
Query: 149 GDYVCQISDRVARDQVHTVEVL----VPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
G Y C S+ + +L VPP P + V G + +C G
Sbjct: 3849 GQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVS--VDLALGESGTFKCHVTGTAPI 3906
Query: 205 TVTWHRLN-------DSSSRLGEGPQ-LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
+TW + N + L E L + ++ + G Y C N G + QL
Sbjct: 3907 KITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSA-QLG 3965
Query: 257 VLYPPEIT--VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP +E S + + F C + P +V WY++ + S + MS S
Sbjct: 3966 VQEPPRFIKKLEPSRIVKQDEF-TRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDS 4024
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
L + ++ ED G+Y+C A N+ G A + + P
Sbjct: 4025 VAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPP 4064
Score = 40.7 bits (91), Expect = 0.012
Identities = 18/56 (32%), Positives = 30/56 (53%)
Query: 288 PPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRAR 343
P ++SWY+ + L S++ +S G HTL + + Q +D GNY V + A+
Sbjct: 5349 PEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVCGPHIASAK 5404
Score = 37.1 bits (82), Expect = 0.14
Identities = 33/128 (25%), Positives = 55/128 (42%), Gaps = 8/128 (6%)
Query: 223 QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP-EITVERSWVHTGEGFRAELV 281
+L ++ + G Y C ++ + T +L++ P + T + E A
Sbjct: 5465 KLTIADVRAEDQGQYTCKYED-----LETSAELRIEAEPIQFTKRIQNIVVSEHQSATFE 5519
Query: 282 CTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVAD-NSLG 340
C V D A V+WY+ L+ S++ G H + I +V P+D G YS +A G
Sbjct: 5520 CEVSFDD-AIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRG 5578
Query: 341 RARRHVEV 348
AR E+
Sbjct: 5579 EARSTAEL 5586
Score = 34.7 bits (76), Expect = 0.76
Identities = 19/89 (21%), Positives = 38/89 (42%)
Query: 252 EFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA 311
E ++++ P I + + G A+ C + + P W++ + S++ ++ +
Sbjct: 112 EIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRS 171
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLG 340
+L I Q D G Y+C A N G
Sbjct: 172 SKYISSLEILRTQVVDCGEYTCKASNEYG 200
Score = 34.7 bits (76), Expect = 0.76
Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 4/71 (5%)
Query: 288 PPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE 347
P + W++N L R H L IADV+ ED G Y+C ++ A +E
Sbjct: 5436 PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIE 5495
Query: 348 VSGRPGPARFT 358
P +FT
Sbjct: 5496 AE----PIQFT 5502
Score = 31.1 bits (67), Expect = 9.4
Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
Query: 25 PRFLSRGHSFRTVVGDTLLLPCQVQNLGSLVLLWRRAPAVLT-AASLMVTRDERFRLVDG 83
P FLSR S T VG C V + +W++ A L+ + + ++ E +++
Sbjct: 216 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILEL 275
Query: 84 YNLQITDVG 92
NL I D G
Sbjct: 276 SNLTIQDRG 284
>S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein.
Length = 848
Score = 82.6 bits (195), Expect = 3e-15
Identities = 82/330 (24%), Positives = 139/330 (42%), Gaps = 34/330 (10%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D +Y+C I++ A +Q T+ + V + + L C A+G+P+P++
Sbjct: 281 DEAEYIC-IAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSI 339
Query: 207 TWH---RLNDSSSRLGEG----------PQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
TW R S + +G L L ++ G Y CT N +G + +
Sbjct: 340 TWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMY 399
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS--FPLSASERVTMSA 311
L+V Y P++ + V+T EG + + C V A P A +SW+++ P S + +
Sbjct: 400 -LEVQYAPKLQGPVA-VYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYN 457
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARA-PHSYT 370
S L + DFGNY+C A N +G+ + P +SP + + P+S T
Sbjct: 458 TPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTP---SSPSIDQVEPYSST 514
Query: 371 LSFAVDSYPPLDELRLL-YRQ--LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRG 427
D + +L Y+ A+ E +W+D A + +G +T + G
Sbjct: 515 AQVQFDEPEATGGVPILKYKAEWRAVGEEVWH-SKWYDAKEA--SMEGIVT------IVG 565
Query: 428 LQPAAVYEAIVQAKNRYGWNEVSDIFQFHT 457
L+P Y + A N G E+S +F T
Sbjct: 566 LKPETTYAVRLAALNGKGLGEISAASEFKT 595
Score = 69.3 bits (162), Expect = 3e-11
Identities = 51/213 (23%), Positives = 94/213 (44%), Gaps = 20/213 (9%)
Query: 147 DAGDYVCQISDRVARDQVH----TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNP 202
D G Y C+ +AR +++ V V VPP+++A + TA G + L C A G P
Sbjct: 183 DEGTYRCE-GRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFP 241
Query: 203 VPTVTWHRLNDSSSR---------LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
PT++W + + + + QL + +++++ Y C +N G T
Sbjct: 242 EPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDAT-I 300
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASER-----VT 308
L+V P+IT + + L C DP ++W ++ +S+ E+ +
Sbjct: 301 HLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMV 360
Query: 309 MSARGSNHTLLIADVQPEDFGNYSCVADNSLGR 341
+ + +L + +Q D G Y C A N++G+
Sbjct: 361 VRSHARVSSLTLKSIQYTDAGEYICTASNTIGQ 393
Score = 46.8 bits (106), Expect = 2e-04
Identities = 52/227 (22%), Positives = 84/227 (37%), Gaps = 13/227 (5%)
Query: 139 TNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRA 198
T + DAG Y C ++ + TV V + + R G AV+ C
Sbjct: 82 TIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDV 141
Query: 199 AGNPVPTVTW-HRLNDSSSR------LGEGPQLQLSRLERHHGGVYACTVD-NGVGPPVV 250
+ PT+ W H+ D + + LQ+ +++ G Y C G
Sbjct: 142 VSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINF 201
Query: 251 TEFQLQVLYPPEITVERSWVH--TGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVT 308
+ Q+ V PP I ++ V+ G LVC P +SW ++ + E
Sbjct: 202 KDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDE 261
Query: 309 MSARGSNHT-LLIADVQPEDFGNYSCVADNSLGR--ARRHVEVSGRP 352
+ + L I V D Y C+A+N G A H++V +P
Sbjct: 262 KYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKP 308
Score = 33.9 bits (74), Expect = 1.3
Identities = 30/134 (22%), Positives = 56/134 (41%), Gaps = 14/134 (10%)
Query: 145 FQDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
+ DAG+Y+C S+ + +D Q +EV P ++ V G + C P
Sbjct: 377 YTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVA---VYTWEGNQVNITCEVFAYPS 433
Query: 204 PTVTWHR-------LNDSSSRLGEGPQ---LQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
T++W R N S+ ++ P L+++ + G Y CT N +G +
Sbjct: 434 ATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFI 493
Query: 254 QLQVLYPPEITVER 267
+Q P ++++
Sbjct: 494 LVQADTPSSPSIDQ 507
>M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteoglycan
protein.
Length = 4391
Score = 82.6 bits (195), Expect = 3e-15
Identities = 68/232 (29%), Positives = 89/232 (38%), Gaps = 22/232 (9%)
Query: 147 DAGDYVCQISDRV--ARDQVHTVE---VLVPPSVRASPETRHVTARRGGAAVLECRAAGN 201
DAG YVC + + A+ QV + + P + + E +T G A L C A G+
Sbjct: 3179 DAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGS 3238
Query: 202 PVPTVTWHRLNDS---SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
P PT+ W +L RL EG L + R+ + G Y C + G T L V
Sbjct: 3239 PAPTIHWSKLRSPLPWQHRL-EGDTLIIPRVAQQDSGQYICNATSPAGHAEAT-IILHVE 3296
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ--NSFPLSASERVTMSARGSNH 316
PP T G +L C PP W + +S P A+ R N
Sbjct: 3297 SPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATAR--------NE 3348
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVE--VSGRPGPARFTSPPLARAP 366
L PED G Y C N +G A + V G PG TS P P
Sbjct: 3349 LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTP 3400
Score = 77.0 bits (181), Expect = 1e-13
Identities = 62/223 (27%), Positives = 94/223 (42%), Gaps = 14/223 (6%)
Query: 149 GDYVCQISDRVARDQVHTVEVLVP-PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
G Y+CQ + Q V+ PSV + T T G A EC A G+P P VT
Sbjct: 3462 GTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQVT 3521
Query: 208 WHRLND--SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITV 265
W ++ + G ++++ +E G Y CT N G + L V P+I++
Sbjct: 3522 WSKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAG-TTQSHVLLLVQALPQISM 3580
Query: 266 ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQP 325
+ V G A C P ++SW + L R+ N+ L++ V+P
Sbjct: 3581 PQE-VRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPDSRL------ENNMLMLPSVRP 3633
Query: 326 EDFGNYSCVADNSLGRAR--RHVEVSGRPGPARFTSPPLARAP 366
+D G Y C A N G+ + H++V R P FT P + P
Sbjct: 3634 QDAGTYVCTATNRQGKVKAFAHLQVPERVVP-YFTQTPYSFLP 3675
Score = 69.3 bits (162), Expect = 3e-11
Identities = 58/219 (26%), Positives = 90/219 (41%), Gaps = 20/219 (9%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHV---------TARRGGAAVLECR 197
D+G+YVC+ + +Q + V VPPS +S R T ++G A +C
Sbjct: 2985 DSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCL 3044
Query: 198 AAGNPVP-TVTW----HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
P ++ W L D+ G + + + G Y C N G +
Sbjct: 3045 IHDGAAPISLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGV-AQSV 3103
Query: 253 FQLQVLYPPEITVERS---WVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTM 309
L V PP ++V WV G+ E C +P + W + S + E+ T
Sbjct: 3104 VNLSVHGPPTVSVLPEGPVWVKVGKAVTLE--CVSAGEPRSSARWTRISSTPAKLEQRTY 3161
Query: 310 SARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
S+ L I+ +P D G Y C+A N+LG A++ VEV
Sbjct: 3162 GLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEV 3200
Score = 67.3 bits (157), Expect = 1e-10
Identities = 68/229 (29%), Positives = 93/229 (40%), Gaps = 31/229 (13%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVL-----------VPPS---VRASPETRHVTARRGGA 191
D+G+YVC++ + + TV VL VP S +R P + HV G
Sbjct: 2111 DSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVA--EGQT 2168
Query: 192 AVLECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP-- 247
L C G VTWH+ S + G L+L ++ G Y C V GP
Sbjct: 2169 LDLNCVVPGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLE 2228
Query: 248 -PVVTEFQLQVLYPP--EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
V+ + V+ P + +E S EG +L C V A+V+WY+ L A
Sbjct: 2229 ASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPAR 2288
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
+V RGS L I P D G Y C A N + A V V+G G
Sbjct: 2289 HQV----RGSR--LYIFQASPADAGQYVCRASNGM-EASITVTVTGTQG 2330
Score = 66.1 bits (154), Expect = 3e-10
Identities = 64/217 (29%), Positives = 86/217 (39%), Gaps = 24/217 (11%)
Query: 147 DAGDYVCQI----SDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNP 202
D Y+C+ +VAR +H V P V+ SPE V A G L CRAAG P
Sbjct: 1927 DQAQYLCRAHSSAGQQVARAVLH-VHGGGGPRVQVSPERTQVHA--GRTVRLYCRAAGVP 1983
Query: 203 VPTVTWHRLNDS-----SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
T+TW + S S + L + + G Y C + G Q+ V
Sbjct: 1984 SATITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGT-AQARMQVVV 2042
Query: 258 LY-----PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
L PP + +E S EG +L C V A+V+WY+ L +V
Sbjct: 2043 LSASDASPPGVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQV----H 2098
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
GS L + V P D G Y C +N G + VS
Sbjct: 2099 GSR--LRLPQVSPADSGEYVCRVENGSGPKEASITVS 2133
Score = 64.9 bits (151), Expect = 6e-10
Identities = 62/212 (29%), Positives = 86/212 (40%), Gaps = 15/212 (7%)
Query: 147 DAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRH---VTARRGGAAVLECRAAGNP 202
DAG YVC S+ A DQ T+ V ++ A + H +T + G A C A G+P
Sbjct: 1834 DAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSP 1893
Query: 203 VPTVTWHRLNDS---SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVV-TEFQLQVL 258
PT+ W + G L+L +E Y C + G V +
Sbjct: 1894 TPTLEWTGGPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGG 1953
Query: 259 YPPEITV--ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
P + V ER+ VH G R L C P A ++W + L R S R
Sbjct: 1954 GGPRVQVSPERTQVHAGRTVR--LYCRAAGVPSATITWRKEGGSLPPQAR---SERTDIA 2008
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
TLLI + D G Y CVA + G A+ ++V
Sbjct: 2009 TLLIPAITTADAGFYLCVATSPAGTAQARMQV 2040
Score = 60.9 bits (141), Expect = 1e-08
Identities = 68/249 (27%), Positives = 96/249 (38%), Gaps = 34/249 (13%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTVEVLVP----PS-------VRASPETRHVTARRGG 190
+M D+G+YVC+ ++ + + V + P PS +R + HV G
Sbjct: 2685 QMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVA--EGE 2742
Query: 191 AAVLECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP- 247
L C G VTWH+ S S G +L+L + G Y C V GP
Sbjct: 2743 TLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPL 2802
Query: 248 ---PVVT-----EFQLQVLYP---PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ 296
+VT + V P P I +E S EG +L C V A+V+W++
Sbjct: 2803 EASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHK 2862
Query: 297 NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRP-GPA 355
L A +V L + V P D G YSC S G V V+ P P
Sbjct: 2863 RGGNLPARHQV------HGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPG 2916
Query: 356 RFTSPPLAR 364
+P LA+
Sbjct: 2917 PIPAPGLAQ 2925
Score = 56.8 bits (131), Expect = 2e-07
Identities = 64/250 (25%), Positives = 93/250 (37%), Gaps = 36/250 (14%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVL----------VPPSVRASPETRHVTARRGGAAVLEC 196
D+G+YVC +S+ + + + V P +R E+ T G L C
Sbjct: 2594 DSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRI--ESSSPTVVEGQTLDLNC 2651
Query: 197 RAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP---PVVT 251
A P +TW++ S S G L+L ++ G Y C +N + +V
Sbjct: 2652 VVARQPQAIITWYKRGGSLPSRHQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVI 2711
Query: 252 EFQLQVLYPPE------ITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE 305
P I +E S H EG +L C V A+V+W++ L +
Sbjct: 2712 SVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHH 2771
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV----EVSGRPG---PARFT 358
+ RGS L + V P D G Y C S G V E SG PA
Sbjct: 2772 Q----TRGSR--LRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGG 2825
Query: 359 SPPLARAPHS 368
+PP+ P S
Sbjct: 2826 APPIRIEPSS 2835
Score = 55.2 bits (127), Expect = 5e-07
Identities = 72/261 (27%), Positives = 104/261 (39%), Gaps = 38/261 (14%)
Query: 147 DAGDYVCQI---SDRVARDQVHTVE------VLVP-----PSVRASPETRHVTARRGGAA 192
D+G+YVC++ S + + T+E V VP P +R P + V G
Sbjct: 2787 DSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVA--EGQTL 2844
Query: 193 VLECRAAGNPVPTVTWHRL--NDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP--- 247
L+C G VTWH+ N + GP L+L+++ G Y+C V G
Sbjct: 2845 DLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEA 2904
Query: 248 PVVTEFQLQVLYP-------PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFP 300
V+ + P I +E S H EG +L C V A+V+WY+
Sbjct: 2905 SVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGS 2964
Query: 301 LSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG---RARRHVEVSGRPGPA-R 356
L A + GS L + V P D G Y C A + G A V V G + R
Sbjct: 2965 LPARHQ----THGSQLRLHL--VSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYR 3018
Query: 357 FTSPPLARAPHSYTLSFAVDS 377
SP ++ P S T+ D+
Sbjct: 3019 LRSPVISIDPPSSTVQQGQDA 3039
Score = 54.4 bits (125), Expect = 9e-07
Identities = 59/237 (24%), Positives = 93/237 (39%), Gaps = 33/237 (13%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASP------------ETRHVTARRGGAAVL 194
D+G+YVC++ V VLV R S E+ + G L
Sbjct: 2497 DSGEYVCRV---VGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDL 2553
Query: 195 ECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPP---- 248
C A T+TW++ S S G +L++ ++ G Y C V NG G
Sbjct: 2554 NCLVASQAPHTITWYKRGGSLPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSL 2613
Query: 249 VVT-----EFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA 303
+VT + + PP I +E S EG +L C V P A ++WY+ L +
Sbjct: 2614 IVTIQGSGSSHVPSVSPP-IRIESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPS 2672
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
+ GS+ L + + D G Y C A+N++ + +S P ++P
Sbjct: 2673 RHQ----THGSH--LRLHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAP 2723
Score = 54.0 bits (124), Expect = 1e-06
Identities = 58/226 (25%), Positives = 89/226 (39%), Gaps = 28/226 (12%)
Query: 147 DAGDYVCQI---SDRVARDQVHTVEVLVPPSVRA---------SPETRHVTARRGGAAVL 194
D+G+Y CQ+ S + + T+E P + A + HVT G L
Sbjct: 2887 DSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVT--EGQTLDL 2944
Query: 195 ECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
C G VTW++ S + G QL+L + G Y C +G GP
Sbjct: 2945 NCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVCRAASGPGPEQEAS 3004
Query: 253 FQLQV---------LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA 303
F + V L P I+++ +G A C ++ D A +S +
Sbjct: 3005 FTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKC-LIHDGAAPISLEWKTRNQEL 3063
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+ V +S GS + I +P + G Y CVA N+ G A+ V +S
Sbjct: 3064 EDNVHISPNGS--IITIVGTRPSNHGTYRCVASNAYGVAQSVVNLS 3107
Score = 52.8 bits (121), Expect = 3e-06
Identities = 34/103 (33%), Positives = 47/103 (45%), Gaps = 6/103 (5%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG Y C ++ Q H + ++ + P+ V A G AAV C A+G P P +
Sbjct: 3549 DAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPA--GSAAVFPCIASGYPTPDI 3606
Query: 207 TWHRLNDS---SSRLGEGPQLQLSRLERHHGGVYACTVDNGVG 246
+W +L+ S SRL E L L + G Y CT N G
Sbjct: 3607 SWSKLDGSLPPDSRL-ENNMLMLPSVRPQDAGTYVCTATNRQG 3648
Score = 50.0 bits (114), Expect = 2e-05
Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 260 PPEI-TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP++ T R + G C + P ++W N + + RVT+++ G TL
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 464
Query: 319 LIADVQPEDFGNYSCVADNSLG 340
+I DV+ D G Y+C A N+ G
Sbjct: 465 IIRDVKESDQGAYTCEAMNARG 486
Score = 49.6 bits (113), Expect = 3e-05
Identities = 69/271 (25%), Positives = 93/271 (34%), Gaps = 29/271 (10%)
Query: 102 TIYENSETSVALAILGATGHTNVWETTRRITSEQHGNTNFRM-IFQ----DAGDYVCQIS 156
T+ E ++ + G W +H R+ IFQ DAG YVC+ S
Sbjct: 2255 TVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRAS 2314
Query: 157 DRVARDQVHTVEV-----LVPPSVRASP---ETRHVTARRGGAAVLECRAAGNPVPTVTW 208
+ + TV L P+ P E G L C G VTW
Sbjct: 2315 NGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTW 2374
Query: 209 HRLNDSSS--RLGEGPQLQLSRLERHHGGVYACTVDNGVGP---PVVTEFQLQVLYP--- 260
H+ S G L+L + G Y C V P V+ + P
Sbjct: 2375 HKRGGSLPVRHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALG 2434
Query: 261 --PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
P + +E S EG +L C V A+V+W++ L A +V GS L
Sbjct: 2435 VTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQV----HGSRLRL 2490
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
L V P D G Y C S G V V+
Sbjct: 2491 L--QVTPADSGEYVCRVVGSSGTQEASVLVT 2519
Score = 45.6 bits (103), Expect = 4e-04
Identities = 48/189 (25%), Positives = 73/189 (38%), Gaps = 20/189 (10%)
Query: 188 RGGAAVLECRAAGNPVPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVD 242
+GG+ L C+ +G+P W R + + + +G +L ++ GVY CT
Sbjct: 1690 QGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSELHFPSVQPSDAGVYICTCR 1749
Query: 243 NGVGPPVVTEFQLQVLYPPE----ITVERSWVHT-GEGFRAELVCTVLADPPAEVSWYQN 297
N + + +L V P +TVE + G +CT + PA Y
Sbjct: 1750 N-LHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPA----YTL 1804
Query: 298 SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL----GRARRHVEVSGR-P 352
+ + ++ A N L I +VQ D G Y C N G A HV+ SG
Sbjct: 1805 VWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLS 1864
Query: 353 GPARFTSPP 361
P PP
Sbjct: 1865 APVVSIHPP 1873
Score = 31.9 bits (69), Expect = 5.4
Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 2/42 (4%)
Query: 171 VPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN 212
+PP V +P + A RG C A G P P + W RLN
Sbjct: 404 MPPQV-VTPPRESIQASRGQTVTFTCVAIGVPTPIINW-RLN 443
>AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteoglycan
2 (perlecan) protein.
Length = 4391
Score = 82.6 bits (195), Expect = 3e-15
Identities = 68/232 (29%), Positives = 89/232 (38%), Gaps = 22/232 (9%)
Query: 147 DAGDYVCQISDRV--ARDQVHTVE---VLVPPSVRASPETRHVTARRGGAAVLECRAAGN 201
DAG YVC + + A+ QV + + P + + E +T G A L C A G+
Sbjct: 3179 DAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGS 3238
Query: 202 PVPTVTWHRLNDS---SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
P PT+ W +L RL EG L + R+ + G Y C + G T L V
Sbjct: 3239 PAPTIHWSKLRSPLPWQHRL-EGDTLIIPRVAQQDSGQYICNATSPAGHAEAT-IILHVE 3296
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ--NSFPLSASERVTMSARGSNH 316
PP T G +L C PP W + +S P A+ R N
Sbjct: 3297 SPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATAR--------NE 3348
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVE--VSGRPGPARFTSPPLARAP 366
L PED G Y C N +G A + V G PG TS P P
Sbjct: 3349 LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTP 3400
Score = 77.0 bits (181), Expect = 1e-13
Identities = 62/223 (27%), Positives = 94/223 (42%), Gaps = 14/223 (6%)
Query: 149 GDYVCQISDRVARDQVHTVEVLVP-PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
G Y+CQ + Q V+ PSV + T T G A EC A G+P P VT
Sbjct: 3462 GTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQVT 3521
Query: 208 WHRLND--SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITV 265
W ++ + G ++++ +E G Y CT N G + L V P+I++
Sbjct: 3522 WSKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAG-TTQSHVLLLVQALPQISM 3580
Query: 266 ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQP 325
+ V G A C P ++SW + L R+ N+ L++ V+P
Sbjct: 3581 PQE-VRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPDSRL------ENNMLMLPSVRP 3633
Query: 326 EDFGNYSCVADNSLGRAR--RHVEVSGRPGPARFTSPPLARAP 366
+D G Y C A N G+ + H++V R P FT P + P
Sbjct: 3634 QDAGTYVCTATNRQGKVKAFAHLQVPERVVP-YFTQTPYSFLP 3675
Score = 69.3 bits (162), Expect = 3e-11
Identities = 58/219 (26%), Positives = 90/219 (41%), Gaps = 20/219 (9%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHV---------TARRGGAAVLECR 197
D+G+YVC+ + +Q + V VPPS +S R T ++G A +C
Sbjct: 2985 DSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCL 3044
Query: 198 AAGNPVP-TVTW----HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
P ++ W L D+ G + + + G Y C N G +
Sbjct: 3045 IHDGAAPISLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGV-AQSV 3103
Query: 253 FQLQVLYPPEITVERS---WVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTM 309
L V PP ++V WV G+ E C +P + W + S + E+ T
Sbjct: 3104 VNLSVHGPPTVSVLPEGPVWVKVGKAVTLE--CVSAGEPRSSARWTRISSTPAKLEQRTY 3161
Query: 310 SARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
S+ L I+ +P D G Y C+A N+LG A++ VEV
Sbjct: 3162 GLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEV 3200
Score = 67.3 bits (157), Expect = 1e-10
Identities = 68/229 (29%), Positives = 93/229 (40%), Gaps = 31/229 (13%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVL-----------VPPS---VRASPETRHVTARRGGA 191
D+G+YVC++ + + TV VL VP S +R P + HV G
Sbjct: 2111 DSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVA--EGQT 2168
Query: 192 AVLECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP-- 247
L C G VTWH+ S + G L+L ++ G Y C V GP
Sbjct: 2169 LDLNCVVPGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLE 2228
Query: 248 -PVVTEFQLQVLYPP--EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
V+ + V+ P + +E S EG +L C V A+V+WY+ L A
Sbjct: 2229 ASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPAR 2288
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
+V RGS L I P D G Y C A N + A V V+G G
Sbjct: 2289 HQV----RGSR--LYIFQASPADAGQYVCRASNGM-EASITVTVTGTQG 2330
Score = 66.5 bits (155), Expect = 2e-10
Identities = 64/217 (29%), Positives = 86/217 (39%), Gaps = 24/217 (11%)
Query: 147 DAGDYVCQI----SDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNP 202
D Y+C+ +VAR +H V P V+ SPE V A G L CRAAG P
Sbjct: 1927 DQAQYLCRAHSSAGQQVARAVLH-VHGGGGPRVQVSPERTQVHA--GRTVRLYCRAAGVP 1983
Query: 203 VPTVTWHRLNDS-----SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
T+TW + S S + L + + G Y C + G Q+ V
Sbjct: 1984 SATITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGT-AQARIQVVV 2042
Query: 258 LY-----PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
L PP + +E S EG +L C V A+V+WY+ L +V
Sbjct: 2043 LSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQV----H 2098
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
GS L + V P D G Y C +N G + VS
Sbjct: 2099 GSR--LRLPQVSPADSGEYVCRVENGSGPKEASITVS 2133
Score = 65.7 bits (153), Expect = 4e-10
Identities = 62/212 (29%), Positives = 86/212 (40%), Gaps = 15/212 (7%)
Query: 147 DAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRH---VTARRGGAAVLECRAAGNP 202
DAG YVC S+ A DQ T+ V ++ A + H +T + G A C A G+P
Sbjct: 1834 DAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSP 1893
Query: 203 VPTVTWHRLNDS---SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVV-TEFQLQVL 258
PT+ W + G L+L +E Y C + G V +
Sbjct: 1894 TPTLEWTGGPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGG 1953
Query: 259 YPPEITV--ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
P + V ER+ VH G R L C P A ++W + L R S R
Sbjct: 1954 GGPRVQVSPERTQVHAGRTVR--LYCRAAGVPSATITWRKEGGSLPPQAR---SERTDIA 2008
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
TLLI + D G Y CVA + G A+ ++V
Sbjct: 2009 TLLIPAITTADAGFYLCVATSPAGTAQARIQV 2040
Score = 60.9 bits (141), Expect = 1e-08
Identities = 68/249 (27%), Positives = 96/249 (38%), Gaps = 34/249 (13%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTVEVLVP----PS-------VRASPETRHVTARRGG 190
+M D+G+YVC+ ++ + + V + P PS +R + HV G
Sbjct: 2685 QMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVA--EGE 2742
Query: 191 AAVLECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP- 247
L C G VTWH+ S S G +L+L + G Y C V GP
Sbjct: 2743 TLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPL 2802
Query: 248 ---PVVT-----EFQLQVLYP---PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ 296
+VT + V P P I +E S EG +L C V A+V+W++
Sbjct: 2803 EASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHK 2862
Query: 297 NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRP-GPA 355
L A +V L + V P D G YSC S G V V+ P P
Sbjct: 2863 RGGNLPARHQV------HGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPG 2916
Query: 356 RFTSPPLAR 364
+P LA+
Sbjct: 2917 PIPAPGLAQ 2925
Score = 56.8 bits (131), Expect = 2e-07
Identities = 64/250 (25%), Positives = 93/250 (37%), Gaps = 36/250 (14%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVL----------VPPSVRASPETRHVTARRGGAAVLEC 196
D+G+YVC +S+ + + + V P +R E+ T G L C
Sbjct: 2594 DSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRI--ESSSPTVVEGQTLDLNC 2651
Query: 197 RAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP---PVVT 251
A P +TW++ S S G L+L ++ G Y C +N + +V
Sbjct: 2652 VVARQPQAIITWYKRGGSLPSRHQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVI 2711
Query: 252 EFQLQVLYPPE------ITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE 305
P I +E S H EG +L C V A+V+W++ L +
Sbjct: 2712 SVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHH 2771
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV----EVSGRPG---PARFT 358
+ RGS L + V P D G Y C S G V E SG PA
Sbjct: 2772 Q----TRGSR--LRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGG 2825
Query: 359 SPPLARAPHS 368
+PP+ P S
Sbjct: 2826 APPIRIEPSS 2835
Score = 55.2 bits (127), Expect = 5e-07
Identities = 72/261 (27%), Positives = 104/261 (39%), Gaps = 38/261 (14%)
Query: 147 DAGDYVCQI---SDRVARDQVHTVE------VLVP-----PSVRASPETRHVTARRGGAA 192
D+G+YVC++ S + + T+E V VP P +R P + V G
Sbjct: 2787 DSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVA--EGQTL 2844
Query: 193 VLECRAAGNPVPTVTWHRL--NDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP--- 247
L+C G VTWH+ N + GP L+L+++ G Y+C V G
Sbjct: 2845 DLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEA 2904
Query: 248 PVVTEFQLQVLYP-------PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFP 300
V+ + P I +E S H EG +L C V A+V+WY+
Sbjct: 2905 SVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGS 2964
Query: 301 LSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG---RARRHVEVSGRPGPA-R 356
L A + GS L + V P D G Y C A + G A V V G + R
Sbjct: 2965 LPARHQ----THGSQLRLHL--VSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYR 3018
Query: 357 FTSPPLARAPHSYTLSFAVDS 377
SP ++ P S T+ D+
Sbjct: 3019 LRSPVISIDPPSSTVQQGQDA 3039
Score = 54.4 bits (125), Expect = 9e-07
Identities = 59/237 (24%), Positives = 93/237 (39%), Gaps = 33/237 (13%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASP------------ETRHVTARRGGAAVL 194
D+G+YVC++ V VLV R S E+ + G L
Sbjct: 2497 DSGEYVCRV---VGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDL 2553
Query: 195 ECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPP---- 248
C A T+TW++ S S G +L++ ++ G Y C V NG G
Sbjct: 2554 NCLVASQAPHTITWYKRGGSLPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSL 2613
Query: 249 VVT-----EFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA 303
+VT + + PP I +E S EG +L C V P A ++WY+ L +
Sbjct: 2614 IVTIQGSGSSHVPSVSPP-IRIESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPS 2672
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
+ GS+ L + + D G Y C A+N++ + +S P ++P
Sbjct: 2673 RHQ----THGSH--LRLHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAP 2723
Score = 54.0 bits (124), Expect = 1e-06
Identities = 58/226 (25%), Positives = 89/226 (39%), Gaps = 28/226 (12%)
Query: 147 DAGDYVCQI---SDRVARDQVHTVEVLVPPSVRA---------SPETRHVTARRGGAAVL 194
D+G+Y CQ+ S + + T+E P + A + HVT G L
Sbjct: 2887 DSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVT--EGQTLDL 2944
Query: 195 ECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
C G VTW++ S + G QL+L + G Y C +G GP
Sbjct: 2945 NCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVCRAASGPGPEQEAS 3004
Query: 253 FQLQV---------LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA 303
F + V L P I+++ +G A C ++ D A +S +
Sbjct: 3005 FTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKC-LIHDGAAPISLEWKTRNQEL 3063
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+ V +S GS + I +P + G Y CVA N+ G A+ V +S
Sbjct: 3064 EDNVHISPNGS--IITIVGTRPSNHGTYRCVASNAYGVAQSVVNLS 3107
Score = 52.8 bits (121), Expect = 3e-06
Identities = 34/103 (33%), Positives = 47/103 (45%), Gaps = 6/103 (5%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG Y C ++ Q H + ++ + P+ V A G AAV C A+G P P +
Sbjct: 3549 DAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPA--GSAAVFPCIASGYPTPDI 3606
Query: 207 TWHRLNDS---SSRLGEGPQLQLSRLERHHGGVYACTVDNGVG 246
+W +L+ S SRL E L L + G Y CT N G
Sbjct: 3607 SWSKLDGSLPPDSRL-ENNMLMLPSVRPQDAGTYVCTATNRQG 3648
Score = 50.0 bits (114), Expect = 2e-05
Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 260 PPEI-TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP++ T R + G C + P ++W N + + RVT+++ G TL
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 464
Query: 319 LIADVQPEDFGNYSCVADNSLG 340
+I DV+ D G Y+C A N+ G
Sbjct: 465 IIRDVKESDQGAYTCEAMNARG 486
Score = 49.6 bits (113), Expect = 3e-05
Identities = 69/271 (25%), Positives = 93/271 (34%), Gaps = 29/271 (10%)
Query: 102 TIYENSETSVALAILGATGHTNVWETTRRITSEQHGNTNFRM-IFQ----DAGDYVCQIS 156
T+ E ++ + G W +H R+ IFQ DAG YVC+ S
Sbjct: 2255 TVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRAS 2314
Query: 157 DRVARDQVHTVEV-----LVPPSVRASP---ETRHVTARRGGAAVLECRAAGNPVPTVTW 208
+ + TV L P+ P E G L C G VTW
Sbjct: 2315 NGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTW 2374
Query: 209 HRLNDSSS--RLGEGPQLQLSRLERHHGGVYACTVDNGVGP---PVVTEFQLQVLYP--- 260
H+ S G L+L + G Y C V P V+ + P
Sbjct: 2375 HKRGGSLPVRHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALG 2434
Query: 261 --PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
P + +E S EG +L C V A+V+W++ L A +V GS L
Sbjct: 2435 VTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQV----HGSRLRL 2490
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
L V P D G Y C S G V V+
Sbjct: 2491 L--QVTPADSGEYVCRVVGSSGTQEASVLVT 2519
Score = 45.6 bits (103), Expect = 4e-04
Identities = 48/189 (25%), Positives = 73/189 (38%), Gaps = 20/189 (10%)
Query: 188 RGGAAVLECRAAGNPVPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVD 242
+GG+ L C+ +G+P W R + + + +G +L ++ GVY CT
Sbjct: 1690 QGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSELHFPSVQPSDAGVYICTCR 1749
Query: 243 NGVGPPVVTEFQLQVLYPPE----ITVERSWVHT-GEGFRAELVCTVLADPPAEVSWYQN 297
N + + +L V P +TVE + G +CT + PA Y
Sbjct: 1750 N-LHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPA----YTL 1804
Query: 298 SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL----GRARRHVEVSGR-P 352
+ + ++ A N L I +VQ D G Y C N G A HV+ SG
Sbjct: 1805 VWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLS 1864
Query: 353 GPARFTSPP 361
P PP
Sbjct: 1865 APVVSIHPP 1873
Score = 31.9 bits (69), Expect = 5.4
Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 2/42 (4%)
Query: 171 VPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN 212
+PP V +P + A RG C A G P P + W RLN
Sbjct: 404 MPPQV-VTPPRESIQASRGQTVTFTCVAIGVPTPIINW-RLN 443
>AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteoglycan
2 (perlecan) protein.
Length = 4391
Score = 82.6 bits (195), Expect = 3e-15
Identities = 68/232 (29%), Positives = 89/232 (38%), Gaps = 22/232 (9%)
Query: 147 DAGDYVCQISDRV--ARDQVHTVE---VLVPPSVRASPETRHVTARRGGAAVLECRAAGN 201
DAG YVC + + A+ QV + + P + + E +T G A L C A G+
Sbjct: 3179 DAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGS 3238
Query: 202 PVPTVTWHRLNDS---SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
P PT+ W +L RL EG L + R+ + G Y C + G T L V
Sbjct: 3239 PAPTIHWSKLRSPLPWQHRL-EGDTLIIPRVAQQDSGQYICNATSPAGHAEAT-IILHVE 3296
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ--NSFPLSASERVTMSARGSNH 316
PP T G +L C PP W + +S P A+ R N
Sbjct: 3297 SPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATAR--------NE 3348
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVE--VSGRPGPARFTSPPLARAP 366
L PED G Y C N +G A + V G PG TS P P
Sbjct: 3349 LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTP 3400
Score = 77.0 bits (181), Expect = 1e-13
Identities = 62/223 (27%), Positives = 94/223 (42%), Gaps = 14/223 (6%)
Query: 149 GDYVCQISDRVARDQVHTVEVLVP-PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
G Y+CQ + Q V+ PSV + T T G A EC A G+P P VT
Sbjct: 3462 GTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQVT 3521
Query: 208 WHRLND--SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITV 265
W ++ + G ++++ +E G Y CT N G + L V P+I++
Sbjct: 3522 WSKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAG-TTQSHVLLLVQALPQISM 3580
Query: 266 ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQP 325
+ V G A C P ++SW + L R+ N+ L++ V+P
Sbjct: 3581 PQE-VRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPDSRL------ENNMLMLPSVRP 3633
Query: 326 EDFGNYSCVADNSLGRAR--RHVEVSGRPGPARFTSPPLARAP 366
+D G Y C A N G+ + H++V R P FT P + P
Sbjct: 3634 QDAGTYVCTATNRQGKVKAFAHLQVPERVVP-YFTQTPYSFLP 3675
Score = 69.3 bits (162), Expect = 3e-11
Identities = 58/219 (26%), Positives = 90/219 (41%), Gaps = 20/219 (9%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHV---------TARRGGAAVLECR 197
D+G+YVC+ + +Q + V VPPS +S R T ++G A +C
Sbjct: 2985 DSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCL 3044
Query: 198 AAGNPVP-TVTW----HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
P ++ W L D+ G + + + G Y C N G +
Sbjct: 3045 IHDGAAPISLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGV-AQSV 3103
Query: 253 FQLQVLYPPEITVERS---WVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTM 309
L V PP ++V WV G+ E C +P + W + S + E+ T
Sbjct: 3104 VNLSVHGPPTVSVLPEGPVWVKVGKAVTLE--CVSAGEPRSSARWTRISSTPAKLEQRTY 3161
Query: 310 SARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
S+ L I+ +P D G Y C+A N+LG A++ VEV
Sbjct: 3162 GLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEV 3200
Score = 67.3 bits (157), Expect = 1e-10
Identities = 68/229 (29%), Positives = 93/229 (40%), Gaps = 31/229 (13%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVL-----------VPPS---VRASPETRHVTARRGGA 191
D+G+YVC++ + + TV VL VP S +R P + HV G
Sbjct: 2111 DSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVA--EGQT 2168
Query: 192 AVLECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP-- 247
L C G VTWH+ S + G L+L ++ G Y C V GP
Sbjct: 2169 LDLNCVVPGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLE 2228
Query: 248 -PVVTEFQLQVLYPP--EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
V+ + V+ P + +E S EG +L C V A+V+WY+ L A
Sbjct: 2229 ASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPAR 2288
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
+V RGS L I P D G Y C A N + A V V+G G
Sbjct: 2289 HQV----RGSR--LYIFQASPADAGQYVCRASNGM-EASITVTVTGTQG 2330
Score = 66.5 bits (155), Expect = 2e-10
Identities = 64/217 (29%), Positives = 86/217 (39%), Gaps = 24/217 (11%)
Query: 147 DAGDYVCQI----SDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNP 202
D Y+C+ +VAR +H V P V+ SPE V A G L CRAAG P
Sbjct: 1927 DQAQYLCRAHSSAGQQVARAVLH-VHGGGGPRVQVSPERTQVHA--GRTVRLYCRAAGVP 1983
Query: 203 VPTVTWHRLNDS-----SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
T+TW + S S + L + + G Y C + G Q+ V
Sbjct: 1984 SATITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGT-AQARIQVVV 2042
Query: 258 LY-----PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
L PP + +E S EG +L C V A+V+WY+ L +V
Sbjct: 2043 LSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQV----H 2098
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
GS L + V P D G Y C +N G + VS
Sbjct: 2099 GSR--LRLPQVSPADSGEYVCRVENGSGPKEASITVS 2133
Score = 65.7 bits (153), Expect = 4e-10
Identities = 62/212 (29%), Positives = 86/212 (40%), Gaps = 15/212 (7%)
Query: 147 DAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRH---VTARRGGAAVLECRAAGNP 202
DAG YVC S+ A DQ T+ V ++ A + H +T + G A C A G+P
Sbjct: 1834 DAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSP 1893
Query: 203 VPTVTWHRLNDS---SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVV-TEFQLQVL 258
PT+ W + G L+L +E Y C + G V +
Sbjct: 1894 TPTLEWTGGPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGG 1953
Query: 259 YPPEITV--ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
P + V ER+ VH G R L C P A ++W + L R S R
Sbjct: 1954 GGPRVQVSPERTQVHAGRTVR--LYCRAAGVPSATITWRKEGGSLPPQAR---SERTDIA 2008
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
TLLI + D G Y CVA + G A+ ++V
Sbjct: 2009 TLLIPAITTADAGFYLCVATSPAGTAQARIQV 2040
Score = 60.9 bits (141), Expect = 1e-08
Identities = 68/249 (27%), Positives = 96/249 (38%), Gaps = 34/249 (13%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTVEVLVP----PS-------VRASPETRHVTARRGG 190
+M D+G+YVC+ ++ + + V + P PS +R + HV G
Sbjct: 2685 QMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVA--EGE 2742
Query: 191 AAVLECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP- 247
L C G VTWH+ S S G +L+L + G Y C V GP
Sbjct: 2743 TLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPL 2802
Query: 248 ---PVVT-----EFQLQVLYP---PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ 296
+VT + V P P I +E S EG +L C V A+V+W++
Sbjct: 2803 EASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHK 2862
Query: 297 NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRP-GPA 355
L A +V L + V P D G YSC S G V V+ P P
Sbjct: 2863 RGGNLPARHQV------HGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPG 2916
Query: 356 RFTSPPLAR 364
+P LA+
Sbjct: 2917 PIPAPGLAQ 2925
Score = 56.8 bits (131), Expect = 2e-07
Identities = 64/250 (25%), Positives = 93/250 (37%), Gaps = 36/250 (14%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVL----------VPPSVRASPETRHVTARRGGAAVLEC 196
D+G+YVC +S+ + + + V P +R E+ T G L C
Sbjct: 2594 DSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRI--ESSSPTVVEGQTLDLNC 2651
Query: 197 RAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP---PVVT 251
A P +TW++ S S G L+L ++ G Y C +N + +V
Sbjct: 2652 VVARQPQAIITWYKRGGSLPSRHQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVI 2711
Query: 252 EFQLQVLYPPE------ITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE 305
P I +E S H EG +L C V A+V+W++ L +
Sbjct: 2712 SVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHH 2771
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV----EVSGRPG---PARFT 358
+ RGS L + V P D G Y C S G V E SG PA
Sbjct: 2772 Q----TRGSR--LRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGG 2825
Query: 359 SPPLARAPHS 368
+PP+ P S
Sbjct: 2826 APPIRIEPSS 2835
Score = 55.2 bits (127), Expect = 5e-07
Identities = 72/261 (27%), Positives = 104/261 (39%), Gaps = 38/261 (14%)
Query: 147 DAGDYVCQI---SDRVARDQVHTVE------VLVP-----PSVRASPETRHVTARRGGAA 192
D+G+YVC++ S + + T+E V VP P +R P + V G
Sbjct: 2787 DSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVA--EGQTL 2844
Query: 193 VLECRAAGNPVPTVTWHRL--NDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP--- 247
L+C G VTWH+ N + GP L+L+++ G Y+C V G
Sbjct: 2845 DLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEA 2904
Query: 248 PVVTEFQLQVLYP-------PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFP 300
V+ + P I +E S H EG +L C V A+V+WY+
Sbjct: 2905 SVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGS 2964
Query: 301 LSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG---RARRHVEVSGRPGPA-R 356
L A + GS L + V P D G Y C A + G A V V G + R
Sbjct: 2965 LPARHQ----THGSQLRLHL--VSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYR 3018
Query: 357 FTSPPLARAPHSYTLSFAVDS 377
SP ++ P S T+ D+
Sbjct: 3019 LRSPVISIDPPSSTVQQGQDA 3039
Score = 54.4 bits (125), Expect = 9e-07
Identities = 59/237 (24%), Positives = 93/237 (39%), Gaps = 33/237 (13%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASP------------ETRHVTARRGGAAVL 194
D+G+YVC++ V VLV R S E+ + G L
Sbjct: 2497 DSGEYVCRV---VGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDL 2553
Query: 195 ECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPP---- 248
C A T+TW++ S S G +L++ ++ G Y C V NG G
Sbjct: 2554 NCLVASQAPHTITWYKRGGSLPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSL 2613
Query: 249 VVT-----EFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA 303
+VT + + PP I +E S EG +L C V P A ++WY+ L +
Sbjct: 2614 IVTIQGSGSSHVPSVSPP-IRIESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPS 2672
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
+ GS+ L + + D G Y C A+N++ + +S P ++P
Sbjct: 2673 RHQ----THGSH--LRLHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAP 2723
Score = 54.0 bits (124), Expect = 1e-06
Identities = 58/226 (25%), Positives = 89/226 (39%), Gaps = 28/226 (12%)
Query: 147 DAGDYVCQI---SDRVARDQVHTVEVLVPPSVRA---------SPETRHVTARRGGAAVL 194
D+G+Y CQ+ S + + T+E P + A + HVT G L
Sbjct: 2887 DSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVT--EGQTLDL 2944
Query: 195 ECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
C G VTW++ S + G QL+L + G Y C +G GP
Sbjct: 2945 NCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVCRAASGPGPEQEAS 3004
Query: 253 FQLQV---------LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA 303
F + V L P I+++ +G A C ++ D A +S +
Sbjct: 3005 FTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKC-LIHDGAAPISLEWKTRNQEL 3063
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+ V +S GS + I +P + G Y CVA N+ G A+ V +S
Sbjct: 3064 EDNVHISPNGS--IITIVGTRPSNHGTYRCVASNAYGVAQSVVNLS 3107
Score = 52.8 bits (121), Expect = 3e-06
Identities = 34/103 (33%), Positives = 47/103 (45%), Gaps = 6/103 (5%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG Y C ++ Q H + ++ + P+ V A G AAV C A+G P P +
Sbjct: 3549 DAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPA--GSAAVFPCIASGYPTPDI 3606
Query: 207 TWHRLNDS---SSRLGEGPQLQLSRLERHHGGVYACTVDNGVG 246
+W +L+ S SRL E L L + G Y CT N G
Sbjct: 3607 SWSKLDGSLPPDSRL-ENNMLMLPSVRPQDAGTYVCTATNRQG 3648
Score = 50.0 bits (114), Expect = 2e-05
Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 260 PPEI-TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP++ T R + G C + P ++W N + + RVT+++ G TL
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 464
Query: 319 LIADVQPEDFGNYSCVADNSLG 340
+I DV+ D G Y+C A N+ G
Sbjct: 465 IIRDVKESDQGAYTCEAMNARG 486
Score = 49.6 bits (113), Expect = 3e-05
Identities = 69/271 (25%), Positives = 93/271 (34%), Gaps = 29/271 (10%)
Query: 102 TIYENSETSVALAILGATGHTNVWETTRRITSEQHGNTNFRM-IFQ----DAGDYVCQIS 156
T+ E ++ + G W +H R+ IFQ DAG YVC+ S
Sbjct: 2255 TVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRAS 2314
Query: 157 DRVARDQVHTVEV-----LVPPSVRASP---ETRHVTARRGGAAVLECRAAGNPVPTVTW 208
+ + TV L P+ P E G L C G VTW
Sbjct: 2315 NGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTW 2374
Query: 209 HRLNDSSS--RLGEGPQLQLSRLERHHGGVYACTVDNGVGP---PVVTEFQLQVLYP--- 260
H+ S G L+L + G Y C V P V+ + P
Sbjct: 2375 HKRGGSLPVRHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALG 2434
Query: 261 --PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
P + +E S EG +L C V A+V+W++ L A +V GS L
Sbjct: 2435 VTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQV----HGSRLRL 2490
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
L V P D G Y C S G V V+
Sbjct: 2491 L--QVTPADSGEYVCRVVGSSGTQEASVLVT 2519
Score = 45.6 bits (103), Expect = 4e-04
Identities = 48/189 (25%), Positives = 73/189 (38%), Gaps = 20/189 (10%)
Query: 188 RGGAAVLECRAAGNPVPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVD 242
+GG+ L C+ +G+P W R + + + +G +L ++ GVY CT
Sbjct: 1690 QGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSELHFPSVQPSDAGVYICTCR 1749
Query: 243 NGVGPPVVTEFQLQVLYPPE----ITVERSWVHT-GEGFRAELVCTVLADPPAEVSWYQN 297
N + + +L V P +TVE + G +CT + PA Y
Sbjct: 1750 N-LHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPA----YTL 1804
Query: 298 SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL----GRARRHVEVSGR-P 352
+ + ++ A N L I +VQ D G Y C N G A HV+ SG
Sbjct: 1805 VWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLS 1864
Query: 353 GPARFTSPP 361
P PP
Sbjct: 1865 APVVSIHPP 1873
Score = 31.9 bits (69), Expect = 5.4
Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 2/42 (4%)
Query: 171 VPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN 212
+PP V +P + A RG C A G P P + W RLN
Sbjct: 404 MPPQV-VTPPRESIQASRGQTVTFTCVAIGVPTPIINW-RLN 443
>AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteoglycan
perlecan protein.
Length = 4370
Score = 82.6 bits (195), Expect = 3e-15
Identities = 68/232 (29%), Positives = 89/232 (38%), Gaps = 22/232 (9%)
Query: 147 DAGDYVCQISDRV--ARDQVHTVE---VLVPPSVRASPETRHVTARRGGAAVLECRAAGN 201
DAG YVC + + A+ QV + + P + + E +T G A L C A G+
Sbjct: 3158 DAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGS 3217
Query: 202 PVPTVTWHRLNDS---SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
P PT+ W +L RL EG L + R+ + G Y C + G T L V
Sbjct: 3218 PAPTIHWSKLRSPLPWQHRL-EGDTLIIPRVAQQDSGQYICNATSPAGHAEAT-IILHVE 3275
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ--NSFPLSASERVTMSARGSNH 316
PP T G +L C PP W + +S P A+ R N
Sbjct: 3276 SPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATAR--------NE 3327
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVE--VSGRPGPARFTSPPLARAP 366
L PED G Y C N +G A + V G PG TS P P
Sbjct: 3328 LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTP 3379
Score = 77.0 bits (181), Expect = 1e-13
Identities = 62/223 (27%), Positives = 94/223 (42%), Gaps = 14/223 (6%)
Query: 149 GDYVCQISDRVARDQVHTVEVLVP-PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
G Y+CQ + Q V+ PSV + T T G A EC A G+P P VT
Sbjct: 3441 GTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQVT 3500
Query: 208 WHRLND--SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITV 265
W ++ + G ++++ +E G Y CT N G + L V P+I++
Sbjct: 3501 WSKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAG-TTQSHVLLLVQALPQISM 3559
Query: 266 ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQP 325
+ V G A C P ++SW + L R+ N+ L++ V+P
Sbjct: 3560 PQE-VRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPDSRL------ENNMLMLPSVRP 3612
Query: 326 EDFGNYSCVADNSLGRAR--RHVEVSGRPGPARFTSPPLARAP 366
+D G Y C A N G+ + H++V R P FT P + P
Sbjct: 3613 QDAGTYVCTATNRQGKVKAFAHLQVPERVVP-YFTQTPYSFLP 3654
Score = 69.3 bits (162), Expect = 3e-11
Identities = 58/219 (26%), Positives = 90/219 (41%), Gaps = 20/219 (9%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHV---------TARRGGAAVLECR 197
D+G+YVC+ + +Q + V VPPS +S R T ++G A +C
Sbjct: 2964 DSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCL 3023
Query: 198 AAGNPVP-TVTW----HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
P ++ W L D+ G + + + G Y C N G +
Sbjct: 3024 IHDGAAPISLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGV-AQSV 3082
Query: 253 FQLQVLYPPEITVERS---WVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTM 309
L V PP ++V WV G+ E C +P + W + S + E+ T
Sbjct: 3083 VNLSVHGPPTVSVLPEGPVWVKVGKAVTLE--CVSAGEPRSSARWTRISSTPAKLEQRTY 3140
Query: 310 SARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
S+ L I+ +P D G Y C+A N+LG A++ VEV
Sbjct: 3141 GLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEV 3179
Score = 67.3 bits (157), Expect = 1e-10
Identities = 68/229 (29%), Positives = 93/229 (40%), Gaps = 31/229 (13%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVL-----------VPPS---VRASPETRHVTARRGGA 191
D+G+YVC++ + + TV VL VP S +R P + HV G
Sbjct: 2090 DSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVA--EGQT 2147
Query: 192 AVLECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP-- 247
L C G VTWH+ S + G L+L ++ G Y C V GP
Sbjct: 2148 LDLNCVVPGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLE 2207
Query: 248 -PVVTEFQLQVLYPP--EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
V+ + V+ P + +E S EG +L C V A+V+WY+ L A
Sbjct: 2208 ASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPAR 2267
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
+V RGS L I P D G Y C A N + A V V+G G
Sbjct: 2268 HQV----RGSR--LYIFQASPADAGQYVCRASNGM-EASITVTVTGTQG 2309
Score = 66.5 bits (155), Expect = 2e-10
Identities = 64/217 (29%), Positives = 86/217 (39%), Gaps = 24/217 (11%)
Query: 147 DAGDYVCQI----SDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNP 202
D Y+C+ +VAR +H V P V+ SPE V A G L CRAAG P
Sbjct: 1906 DQAQYLCRAHSSAGQQVARAVLH-VHGGGGPRVQVSPERTQVHA--GRTVRLYCRAAGVP 1962
Query: 203 VPTVTWHRLNDS-----SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
T+TW + S S + L + + G Y C + G Q+ V
Sbjct: 1963 SATITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGT-AQARIQVVV 2021
Query: 258 LY-----PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
L PP + +E S EG +L C V A+V+WY+ L +V
Sbjct: 2022 LSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQV----H 2077
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
GS L + V P D G Y C +N G + VS
Sbjct: 2078 GSR--LRLPQVSPADSGEYVCRVENGSGPKEASITVS 2112
Score = 65.7 bits (153), Expect = 4e-10
Identities = 62/212 (29%), Positives = 86/212 (40%), Gaps = 15/212 (7%)
Query: 147 DAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRH---VTARRGGAAVLECRAAGNP 202
DAG YVC S+ A DQ T+ V ++ A + H +T + G A C A G+P
Sbjct: 1813 DAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSP 1872
Query: 203 VPTVTWHRLNDS---SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVV-TEFQLQVL 258
PT+ W + G L+L +E Y C + G V +
Sbjct: 1873 TPTLEWTGGPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGG 1932
Query: 259 YPPEITV--ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
P + V ER+ VH G R L C P A ++W + L R S R
Sbjct: 1933 GGPRVQVSPERTQVHAGRTVR--LYCRAAGVPSATITWRKEGGSLPPQAR---SERTDIA 1987
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
TLLI + D G Y CVA + G A+ ++V
Sbjct: 1988 TLLIPAITTADAGFYLCVATSPAGTAQARIQV 2019
Score = 60.9 bits (141), Expect = 1e-08
Identities = 68/249 (27%), Positives = 96/249 (38%), Gaps = 34/249 (13%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTVEVLVP----PS-------VRASPETRHVTARRGG 190
+M D+G+YVC+ ++ + + V + P PS +R + HV G
Sbjct: 2664 QMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVA--EGE 2721
Query: 191 AAVLECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP- 247
L C G VTWH+ S S G +L+L + G Y C V GP
Sbjct: 2722 TLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPL 2781
Query: 248 ---PVVT-----EFQLQVLYP---PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ 296
+VT + V P P I +E S EG +L C V A+V+W++
Sbjct: 2782 EASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHK 2841
Query: 297 NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRP-GPA 355
L A +V L + V P D G YSC S G V V+ P P
Sbjct: 2842 RGGNLPARHQV------HGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPG 2895
Query: 356 RFTSPPLAR 364
+P LA+
Sbjct: 2896 PIPAPGLAQ 2904
Score = 56.8 bits (131), Expect = 2e-07
Identities = 64/250 (25%), Positives = 93/250 (37%), Gaps = 36/250 (14%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVL----------VPPSVRASPETRHVTARRGGAAVLEC 196
D+G+YVC +S+ + + + V P +R E+ T G L C
Sbjct: 2573 DSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRI--ESSSPTVVEGQTLDLNC 2630
Query: 197 RAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP---PVVT 251
A P +TW++ S S G L+L ++ G Y C +N + +V
Sbjct: 2631 VVARQPQAIITWYKRGGSLPSRHQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVI 2690
Query: 252 EFQLQVLYPPE------ITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE 305
P I +E S H EG +L C V A+V+W++ L +
Sbjct: 2691 SVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHH 2750
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV----EVSGRPG---PARFT 358
+ RGS L + V P D G Y C S G V E SG PA
Sbjct: 2751 Q----TRGSR--LRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGG 2804
Query: 359 SPPLARAPHS 368
+PP+ P S
Sbjct: 2805 APPIRIEPSS 2814
Score = 55.2 bits (127), Expect = 5e-07
Identities = 72/261 (27%), Positives = 104/261 (39%), Gaps = 38/261 (14%)
Query: 147 DAGDYVCQI---SDRVARDQVHTVE------VLVP-----PSVRASPETRHVTARRGGAA 192
D+G+YVC++ S + + T+E V VP P +R P + V G
Sbjct: 2766 DSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVA--EGQTL 2823
Query: 193 VLECRAAGNPVPTVTWHRL--NDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP--- 247
L+C G VTWH+ N + GP L+L+++ G Y+C V G
Sbjct: 2824 DLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEA 2883
Query: 248 PVVTEFQLQVLYP-------PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFP 300
V+ + P I +E S H EG +L C V A+V+WY+
Sbjct: 2884 SVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGS 2943
Query: 301 LSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG---RARRHVEVSGRPGPA-R 356
L A + GS L + V P D G Y C A + G A V V G + R
Sbjct: 2944 LPARHQ----THGSQLRLHL--VSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYR 2997
Query: 357 FTSPPLARAPHSYTLSFAVDS 377
SP ++ P S T+ D+
Sbjct: 2998 LRSPVISIDPPSSTVQQGQDA 3018
Score = 54.4 bits (125), Expect = 9e-07
Identities = 59/237 (24%), Positives = 93/237 (39%), Gaps = 33/237 (13%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASP------------ETRHVTARRGGAAVL 194
D+G+YVC++ V VLV R S E+ + G L
Sbjct: 2476 DSGEYVCRV---VGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDL 2532
Query: 195 ECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPP---- 248
C A T+TW++ S S G +L++ ++ G Y C V NG G
Sbjct: 2533 NCLVASQAPHTITWYKRGGSLPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSL 2592
Query: 249 VVT-----EFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA 303
+VT + + PP I +E S EG +L C V P A ++WY+ L +
Sbjct: 2593 IVTIQGSGSSHVPSVSPP-IRIESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPS 2651
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
+ GS+ L + + D G Y C A+N++ + +S P ++P
Sbjct: 2652 RHQ----THGSH--LRLHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAP 2702
Score = 54.0 bits (124), Expect = 1e-06
Identities = 58/226 (25%), Positives = 89/226 (39%), Gaps = 28/226 (12%)
Query: 147 DAGDYVCQI---SDRVARDQVHTVEVLVPPSVRA---------SPETRHVTARRGGAAVL 194
D+G+Y CQ+ S + + T+E P + A + HVT G L
Sbjct: 2866 DSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVT--EGQTLDL 2923
Query: 195 ECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
C G VTW++ S + G QL+L + G Y C +G GP
Sbjct: 2924 NCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVCRAASGPGPEQEAS 2983
Query: 253 FQLQV---------LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA 303
F + V L P I+++ +G A C ++ D A +S +
Sbjct: 2984 FTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKC-LIHDGAAPISLEWKTRNQEL 3042
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+ V +S GS + I +P + G Y CVA N+ G A+ V +S
Sbjct: 3043 EDNVHISPNGS--IITIVGTRPSNHGTYRCVASNAYGVAQSVVNLS 3086
Score = 52.8 bits (121), Expect = 3e-06
Identities = 34/103 (33%), Positives = 47/103 (45%), Gaps = 6/103 (5%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG Y C ++ Q H + ++ + P+ V A G AAV C A+G P P +
Sbjct: 3528 DAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPA--GSAAVFPCIASGYPTPDI 3585
Query: 207 TWHRLNDS---SSRLGEGPQLQLSRLERHHGGVYACTVDNGVG 246
+W +L+ S SRL E L L + G Y CT N G
Sbjct: 3586 SWSKLDGSLPPDSRL-ENNMLMLPSVRPQDAGTYVCTATNRQG 3627
Score = 50.0 bits (114), Expect = 2e-05
Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 260 PPEI-TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP++ T R + G C + P ++W N + + RVT+++ G TL
Sbjct: 384 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 443
Query: 319 LIADVQPEDFGNYSCVADNSLG 340
+I DV+ D G Y+C A N+ G
Sbjct: 444 IIRDVKESDQGAYTCEAMNARG 465
Score = 49.6 bits (113), Expect = 3e-05
Identities = 69/271 (25%), Positives = 93/271 (34%), Gaps = 29/271 (10%)
Query: 102 TIYENSETSVALAILGATGHTNVWETTRRITSEQHGNTNFRM-IFQ----DAGDYVCQIS 156
T+ E ++ + G W +H R+ IFQ DAG YVC+ S
Sbjct: 2234 TVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRAS 2293
Query: 157 DRVARDQVHTVEV-----LVPPSVRASP---ETRHVTARRGGAAVLECRAAGNPVPTVTW 208
+ + TV L P+ P E G L C G VTW
Sbjct: 2294 NGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTW 2353
Query: 209 HRLNDSSS--RLGEGPQLQLSRLERHHGGVYACTVDNGVGP---PVVTEFQLQVLYP--- 260
H+ S G L+L + G Y C V P V+ + P
Sbjct: 2354 HKRGGSLPVRHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALG 2413
Query: 261 --PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
P + +E S EG +L C V A+V+W++ L A +V GS L
Sbjct: 2414 VTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQV----HGSRLRL 2469
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
L V P D G Y C S G V V+
Sbjct: 2470 L--QVTPADSGEYVCRVVGSSGTQEASVLVT 2498
Score = 45.6 bits (103), Expect = 4e-04
Identities = 48/189 (25%), Positives = 73/189 (38%), Gaps = 20/189 (10%)
Query: 188 RGGAAVLECRAAGNPVPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVD 242
+GG+ L C+ +G+P W R + + + +G +L ++ GVY CT
Sbjct: 1669 QGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSELHFPSVQPSDAGVYICTCR 1728
Query: 243 NGVGPPVVTEFQLQVLYPPE----ITVERSWVHT-GEGFRAELVCTVLADPPAEVSWYQN 297
N + + +L V P +TVE + G +CT + PA Y
Sbjct: 1729 N-LHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPA----YTL 1783
Query: 298 SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL----GRARRHVEVSGR-P 352
+ + ++ A N L I +VQ D G Y C N G A HV+ SG
Sbjct: 1784 VWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLS 1843
Query: 353 GPARFTSPP 361
P PP
Sbjct: 1844 APVVSIHPP 1852
Score = 31.9 bits (69), Expect = 5.4
Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 2/42 (4%)
Query: 171 VPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN 212
+PP V +P + A RG C A G P P + W RLN
Sbjct: 383 MPPQV-VTPPRESIQASRGQTVTFTCVAIGVPTPIINW-RLN 422
>AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.
Length = 30000
Score = 82.6 bits (195), Expect = 3e-15
Identities = 59/218 (27%), Positives = 91/218 (41%), Gaps = 11/218 (5%)
Query: 147 DAGDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D+G Y+CQ+S+ V T+ V PP P V R G + EC+ G P
Sbjct: 5761 DSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVL-RNGQSTTFECQITGTPKIR 5819
Query: 206 VTWHRLNDSSSRLGEG--------PQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V+W+ + + + + Q+S + G Y C N G + +L+V
Sbjct: 5820 VSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCS-IELKV 5878
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP E V + EL C V PP EV+W +N+ + +S++ T++ R S
Sbjct: 5879 KEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFN 5938
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L I P D G Y C+ N G V+ + P+
Sbjct: 5939 LHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPS 5976
Score = 82.6 bits (195), Expect = 3e-15
Identities = 72/263 (27%), Positives = 112/263 (42%), Gaps = 17/263 (6%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D+G Y CQ ++ V +D + V PP E V A++G + LEC+ +G+P
Sbjct: 7264 DSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKV-AKQGESIQLECKISGSPEIK 7322
Query: 206 VTWHRLNDSS---------SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
V+W R NDS S + L ++ G Y C NGVG + L
Sbjct: 7323 VSWFR-NDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCST-ALT 7380
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
V PP T + S V +G L C + PP EV W ++ + S++ ++++ +
Sbjct: 7381 VKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDT 7440
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFT---SPPLARAPHSYTLSF 373
+L I +++ D G Y C A N +G V + P RF S + L
Sbjct: 7441 SLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKE-PPRFVKKLSDTSTLIGDAVELRA 7499
Query: 374 AVDSYPPLDELRLLYRQLAINES 396
V+ + P+ + L R I ES
Sbjct: 7500 IVEGFQPISVVWLKDRGEVIRES 7522
Score = 77.4 bits (182), Expect = 1e-13
Identities = 59/226 (26%), Positives = 96/226 (42%), Gaps = 15/226 (6%)
Query: 147 DAGDYVCQI-SDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+AG Y CQI +D ++ T+ VL P ++ PE+ VT G LEC AG P +
Sbjct: 8486 NAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTT--GDTCTLECTVAGTPELS 8543
Query: 206 VTWHR-----LNDSSSRLG---EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
W + +D+ ++ + L++ + GVY+ V N VG T LQV
Sbjct: 8544 TKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTA-SLQV 8602
Query: 258 ---LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
PP T + + G + C V PP VSW+ +S+ + + +
Sbjct: 8603 SDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDN 8662
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
L + ++ D G+Y+C+A N G ++ R P+ P
Sbjct: 8663 TCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKP 8708
Score = 76.2 bits (179), Expect = 3e-13
Identities = 54/216 (25%), Positives = 94/216 (43%), Gaps = 13/216 (6%)
Query: 137 GNTNFRMIFQ-DA---GDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAA 192
G+T+F ++ DA G Y C +++ V D T+ ++ P + G ++
Sbjct: 6309 GSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSS 6368
Query: 193 VLECRAAGNPVPTVTW----HRLNDSSSR----LGEGPQLQLSRLERHHGGVYACTVDNG 244
LEC+ AG+P V W H L S + +Q++ L G + C N
Sbjct: 6369 RLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNP 6428
Query: 245 VGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
G + ++ V PP + V T + L C + PP EV WY++ L +S
Sbjct: 6429 AGSTSCST-KVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSS 6487
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
++ ++++ + ++ I +V D G Y C A N +G
Sbjct: 6488 KKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVG 6523
Score = 76.2 bits (179), Expect = 3e-13
Identities = 59/218 (27%), Positives = 88/218 (40%), Gaps = 15/218 (6%)
Query: 146 QDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C+I + RD V L PP E + A G + L+C+ AG P
Sbjct: 6978 RDAGQYSCEIENEAGRDVCGALVSTLEPPYFVT--ELEPLEAAVGDSVSLQCQVAGTPEI 7035
Query: 205 TVTWHRLNDSSSR---------LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVV-TEFQ 254
TV+W++ D+ R L +++ + G Y C +N +G T F+
Sbjct: 7036 TVSWYK-GDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFR 7094
Query: 255 LQVLY-PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
+Q PP + + G L C + P +V WY++ L E + S
Sbjct: 7095 IQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVD 7154
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR 351
+ TL I G YSC A N LG A ++ R
Sbjct: 7155 NVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAR 7192
Score = 72.9 bits (171), Expect = 2e-12
Identities = 60/210 (28%), Positives = 87/210 (41%), Gaps = 17/210 (8%)
Query: 146 QDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C I + +D + +L PP E V+ G +A L+C+ AG P
Sbjct: 8860 EDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSV--GDSASLQCQLAGTPEI 8917
Query: 205 TVTWHRLNDSSSR---------LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF-- 253
V+W++ D+ R L ++++ + G Y C +N VG + F
Sbjct: 8918 GVSWYK-GDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLT 8976
Query: 254 -QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
Q Q L PP + + V G C + P VSWY++ PL S V S
Sbjct: 8977 VQEQKL-PPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFL 9035
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+ TL I G YSC A N +G A
Sbjct: 9036 DNTATLNIFKTDRSLAGQYSCTATNPIGSA 9065
Score = 72.9 bits (171), Expect = 2e-12
Identities = 61/224 (27%), Positives = 93/224 (41%), Gaps = 17/224 (7%)
Query: 147 DAGDYVCQISDRVARD----QVHTVEVLVPPS-VRASPETRHVTARRGGAAVLECRAAGN 201
D+G Y C + V +D Q++ E L+PPS + ET V G + LE R AG+
Sbjct: 9146 DSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSET--VEETEGNSFKLEGRVAGS 9203
Query: 202 PVPTVTWHRLN-----DSSSRL---GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
TV W++ N S+ + LQ+ + + G+Y C V N G + T
Sbjct: 9204 QPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSS 9263
Query: 254 QL--QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA 311
+ + PP + V EG +L C V P + W + + S+R + S
Sbjct: 9264 IVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSF 9323
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
L + DV D G+Y C A N G +V+ + PA
Sbjct: 9324 ASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPA 9367
Score = 71.3 bits (167), Expect = 7e-12
Identities = 53/205 (25%), Positives = 86/205 (41%), Gaps = 11/205 (5%)
Query: 146 QDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D+G YVC S+ TV V PPS + ++ G +A L C+ G+PV
Sbjct: 4636 KDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLP-GESARLHCKLKGSPVI 4694
Query: 205 TVTWHRLNDSSSR--------LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
VTW + N S + L ++ ++ G Y+C N VG + ++
Sbjct: 4695 QVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCST-EIV 4753
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
+ PP G A L C V P E+SW+++ + +S++ + ++ S
Sbjct: 4754 IKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLV 4813
Query: 317 TLLIADVQPEDFGNYSCVADNSLGR 341
L I D G Y CV N +G+
Sbjct: 4814 CLEIFSFNSADVGEYECVVANEVGK 4838
Score = 71.3 bits (167), Expect = 7e-12
Identities = 53/183 (28%), Positives = 81/183 (44%), Gaps = 13/183 (7%)
Query: 189 GGAAVLECRAAGNPVPTVTWHRLND--------SSSRLGEGPQLQLSRLERHHGGVYACT 240
G +A EC G +TW + N + + +G P L++ ++ + G Y C
Sbjct: 7212 GESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQ 7271
Query: 241 VDNGVGPPVVTEFQLQVLYPPEIT--VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS 298
N VG + + QL V PP+ +E S V +G +L C + P +VSW++N
Sbjct: 7272 ATNDVGKDMCSA-QLSVKEPPKFVKKLEASKV-AKQGESIQLECKISGSPEIKVSWFRND 7329
Query: 299 FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFT 358
L S + MS S L I + ED G+Y C A N +G A ++ + P FT
Sbjct: 7330 SELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPV-FT 7388
Query: 359 SPP 361
P
Sbjct: 7389 QKP 7391
Score = 71.3 bits (167), Expect = 7e-12
Identities = 58/209 (27%), Positives = 88/209 (42%), Gaps = 17/209 (8%)
Query: 147 DAGDYVCQISDRVARDQ----VHTVEVLVPPS-VRASPETRHVTARRGGAAVLECRAAGN 201
D+G Y ++ + V +D + + VPPS R ET ++ G + V+EC+ G+
Sbjct: 8579 DSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLS---GSSVVMECKVYGS 8635
Query: 202 PVPTVTW-HRLNDSSS------RLGEGP-QLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
P +V+W H N+ SS L + L ++ LE G Y C N G +
Sbjct: 8636 PPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSA- 8694
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
L V PP + + G V PP VSW++ S L +R +S
Sbjct: 8695 PLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLED 8754
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRA 342
S L + DV G Y+C+ N G+A
Sbjct: 8755 SVAELELFDVDTSQSGEYTCIVSNEAGKA 8783
Score = 70.9 bits (166), Expect = 1e-11
Identities = 58/208 (27%), Positives = 84/208 (40%), Gaps = 15/208 (7%)
Query: 147 DAGDYVCQISDRVARDQ----VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNP 202
D G Y ++ + V + VH + +VPPS + + V A G + VLECR +G+
Sbjct: 7638 DKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIR--KLKDVNAILGASVVLECRVSGSA 7695
Query: 203 VPTVTWHRLNDS-------SSRLGEGP-QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
+V W + + S E L LS LE G+Y C N G +
Sbjct: 7696 PISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAV- 7754
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
L V PP V G + PP +V W++ S L E +S
Sbjct: 7755 LTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDF 7814
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRA 342
L + +VQP + G+YSC+ N G A
Sbjct: 7815 VTELELFEVQPLESGDYSCLVTNDAGSA 7842
Score = 70.1 bits (164), Expect = 2e-11
Identities = 52/210 (24%), Positives = 83/210 (39%), Gaps = 17/210 (8%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+D Y C I + +D + ++ P P HV A G A L+C+ G P
Sbjct: 7919 EDYAQYSCLIENEAGQDICEALVSVLEPPYFIEP-LEHVEAVIGEPATLQCKVDGTPEIR 7977
Query: 206 VTWHRLNDSSSRLGEGP-----------QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
++W++ ++L P L +++++ G Y+C DN VG +
Sbjct: 7978 ISWYK---EHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVL 8034
Query: 255 L--QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
+ + PP + VH GF C + P +VSWY++ L + S
Sbjct: 8035 VIKERKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFV 8094
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+ TL I G Y+C A N LG A
Sbjct: 8095 HNVATLQILQTDQSHIGQYNCSASNPLGTA 8124
Score = 68.5 bits (160), Expect = 5e-11
Identities = 58/210 (27%), Positives = 87/210 (41%), Gaps = 15/210 (7%)
Query: 142 RMIFQDAGDYVCQISDRV-ARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
R+ DAG++ C+ ++ V ++D + V PPS P ++ V G A L+ G
Sbjct: 5101 RVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLP--GSAVCLKSTFQG 5158
Query: 201 NPVPTVTWHRLNDSSSRLGE--------GPQLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
+ T+ W + N G L+L ++ G Y C V N G V
Sbjct: 5159 STPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGG-VECS 5217
Query: 253 FQLQVLYPPEIT--VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
L V P +E S + +G +L C V PP +++W+ N + S + MS
Sbjct: 5218 ANLFVKEPATFVEKLEPSQL-LKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMS 5276
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
S L + DV ED G Y C A N G
Sbjct: 5277 FVESTAVLRLTDVGIEDSGEYMCEAQNEAG 5306
Score = 68.5 bits (160), Expect = 5e-11
Identities = 51/203 (25%), Positives = 83/203 (40%), Gaps = 11/203 (5%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
DAG Y C S+ +D + V PP E + ++ EC+ G+P
Sbjct: 8205 DAGQYTCYASNIAGKDSCSAHLGVQEPPRFIKKLEPSRIV-KQDEFTRYECKIGGSPEIK 8263
Query: 206 VTWHR----LNDSS----SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V W++ + +SS S + L++ L G Y C N G + L+V
Sbjct: 8264 VLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGS-ASSSTSLKV 8322
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP + + T +G L C + PP VSWY++ L + ++ + + +
Sbjct: 8323 KEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTS 8382
Query: 318 LLIADVQPEDFGNYSCVADNSLG 340
+ I +V D G Y C A N +G
Sbjct: 8383 IHILNVDAADIGEYQCKATNDVG 8405
Score = 68.5 bits (160), Expect = 5e-11
Identities = 58/228 (25%), Positives = 99/228 (43%), Gaps = 18/228 (7%)
Query: 147 DAGDYVCQISDRVARDQVHTV----EVLVPPSVRASPETRHVTARRGGAAVLECRAAGNP 202
D+G+Y+C+ + V T E +PPS S + R V G V +C +G+
Sbjct: 8954 DSGEYICKAENSVGEVSASTFLTVQEQKLPPSF--SRQLRDVQETVGLPVVFDCAISGSE 9011
Query: 203 VPTVTWHR----LNDS----SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
+V+W++ L DS +S L L + + +R G Y+CT N +G +
Sbjct: 9012 PISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARL 9071
Query: 255 L--QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
+ + PP + + V G A+ C V P +VSW ++S + + + +S
Sbjct: 9072 ILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYL 9131
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGR--ARRHVEVSGRPGPARFT 358
++ L + V D G Y+C A N +G+ + + R P FT
Sbjct: 9132 ENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT 9179
Score = 66.9 bits (156), Expect = 2e-10
Identities = 60/226 (26%), Positives = 93/226 (41%), Gaps = 19/226 (8%)
Query: 143 MIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNP 202
+ QD G Y C+ S++ D + E+++ E V + LEC+ +
Sbjct: 4540 LTIQDRGVYSCKASNKFGAD-ICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDR 4598
Query: 203 VPTVTWHRLNDSSSRLGEGPQ-----------LQLSRLERHHGGVYACTVDNGVGPPVVT 251
TVTW + +L G L++ + G Y CT N G +
Sbjct: 4599 KVTVTWSK---DGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCS 4655
Query: 252 EFQLQVLYPPEIT--VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTM 309
+ V PP V+ S++ G A L C + P +V+W++N+ LS S V M
Sbjct: 4656 A-TVTVREPPSFVKKVDPSYLML-PGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRM 4713
Query: 310 SARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
S L I DV+ ED G+YSC A N +G E+ + P+
Sbjct: 4714 YFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPS 4759
Score = 66.9 bits (156), Expect = 2e-10
Identities = 49/201 (24%), Positives = 81/201 (40%), Gaps = 10/201 (4%)
Query: 148 AGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
+G+Y C +S+ + T + + + + +G +LE G P +VT
Sbjct: 8769 SGEYTCIVSNEAGKASC-TTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVT 8827
Query: 208 WHR--LNDSSSR------LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
W + +N + S+ + L++ G Y C ++N G + Q+ +L
Sbjct: 8828 WKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSA-QILILE 8886
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
PP + V G A L C + P VSWY+ L + M R + TL+
Sbjct: 8887 PPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLV 8946
Query: 320 IADVQPEDFGNYSCVADNSLG 340
V D G Y C A+NS+G
Sbjct: 8947 FNQVDINDSGEYICKAENSVG 8967
Score = 65.7 bits (153), Expect = 4e-10
Identities = 52/202 (25%), Positives = 79/202 (39%), Gaps = 10/202 (4%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
++GDY C +++ T + V + G VLE G P +V
Sbjct: 7827 ESGDYSCLVTNDAGSASC-TTHLFVKEPATFVKRLADFSVETGSPIVLEATYTGTPPISV 7885
Query: 207 TWHR---LNDSSSRLG-----EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
+W + L S R + L++ Y+C ++N G + E + VL
Sbjct: 7886 SWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDIC-EALVSVL 7944
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP V G A L C V P +SWY+ L ++ M + + +L
Sbjct: 7945 EPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASL 8004
Query: 319 LIADVQPEDFGNYSCVADNSLG 340
+I V D G YSC ADNS+G
Sbjct: 8005 VINKVDHSDVGEYSCKADNSVG 8026
Score = 63.7 bits (148), Expect = 1e-09
Identities = 62/223 (27%), Positives = 90/223 (40%), Gaps = 24/223 (10%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG+Y ++ R R V T+ V P + E + VT + G A +G P P +
Sbjct: 3214 DAGEYTF-VAGR-NRSSV-TLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKI 3270
Query: 207 TWHRLNDSSSR------LGEGPQLQLSRLER--HHGGVYACTVDNGVG------------ 246
+W++ S L +G + L +E VY C N G
Sbjct: 3271 SWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV 3330
Query: 247 PPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASER 306
P VV+ Q +YPP I T EG A C V + +VSWY + S
Sbjct: 3331 PEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIKPSRF 3389
Query: 307 VTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
M+ + L IA+ PED G Y+ VA N++G+ +S
Sbjct: 3390 FRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLS 3432
Score = 63.7 bits (148), Expect = 1e-09
Identities = 60/224 (26%), Positives = 92/224 (41%), Gaps = 15/224 (6%)
Query: 147 DAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G+Y C+ + V D V TV++ PP R + +T G A L+ G
Sbjct: 6510 DIGEYHCKAQNEVGSDTCVCTVKLKEPP--RFVSKLNSLTVVAGEPAELQASIEGAQPIF 6567
Query: 206 VTWHRLNDSSSRLGEGPQ---------LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
V W + + R E + LQ ++ E + G Y C + N G L
Sbjct: 6568 VQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMEE-NMATLM 6626
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
VL P I + + G L C V P V WY++ L++S++ S
Sbjct: 6627 VLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKIS 6686
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRA--RRHVEVSGRPGPARFT 358
+L I V+ +D G Y+ N++G++ V+VS R P FT
Sbjct: 6687 SLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFT 6730
Score = 63.7 bits (148), Expect = 1e-09
Identities = 50/210 (23%), Positives = 82/210 (39%), Gaps = 10/210 (4%)
Query: 141 FRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
F + +G+Y C +S+ + T + P+ + H + G + +LE G
Sbjct: 6880 FNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDH-SVEPGKSIILESTYTG 6938
Query: 201 NPVPTVTWHR--LNDSSSR------LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
+VTW + N ++S + L++ + G Y+C ++N G V
Sbjct: 6939 TLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGA 6998
Query: 253 FQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
+ L PP E + G L C V P VSWY+ L +
Sbjct: 6999 L-VSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFT 7057
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+ TL+ V D G Y+C A+NS+G A
Sbjct: 7058 NNVATLVFNKVNINDSGEYTCKAENSIGTA 7087
Score = 63.3 bits (147), Expect = 2e-09
Identities = 53/177 (29%), Positives = 79/177 (44%), Gaps = 12/177 (6%)
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLND--SSSRL-------GEG-PQLQLSRLERHH 233
V G A E +G PVP V+W R S+S L +G +L + + + +
Sbjct: 15 VVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKAN 74
Query: 234 GGVYACTVDNGVGPPVVT-EFQLQVLYPPEITVERSWVHT-GEGFRAELVCTVLADPPAE 291
G Y+ NG G T E ++ P V+R T +G + L V P
Sbjct: 75 SGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPV 134
Query: 292 VSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
V +Y++ + +S +S G ++LLIA+ PED G YS A NS+GRA E+
Sbjct: 135 VKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAEL 191
Score = 62.5 bits (145), Expect = 3e-09
Identities = 56/220 (25%), Positives = 90/220 (40%), Gaps = 14/220 (6%)
Query: 147 DAGDYVCQISDR---VARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D G+Y C+ S+ V+ TV PP+ + P++ +T G AA C G PV
Sbjct: 4449 DCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKS--LTTFVGKAAKFICTVTGTPV 4506
Query: 204 PTVTWHR----LNDSSS-RLGEGPQ---LQLSRLERHHGGVYACTVDNGVGPPVVTEFQL 255
W + L+ S + ++ + L+LS L GVY+C N G + + +L
Sbjct: 4507 IETIWQKDGAALSPSPNWKISDAENKHILELSNLTIQDRGVYSCKASNKFGADIC-QAEL 4565
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
++ P E V + + L C V D V+W ++ L + +
Sbjct: 4566 IIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKI 4625
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
TL I + +D G Y C A N G + V+ R P+
Sbjct: 4626 ATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPS 4665
Score = 62.1 bits (144), Expect = 4e-09
Identities = 56/224 (25%), Positives = 87/224 (38%), Gaps = 15/224 (6%)
Query: 147 DAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G+Y C+ ++ V D V ++ + PP R + ++ G L+ G +
Sbjct: 8392 DIGEYQCKATNDVGSDTCVGSIALKAPP--RFVKKLSDISTVVGKEVQLQTTIEGAEPIS 8449
Query: 206 VTWHRLNDSSSRLGEG---------PQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
V W + R + LQ SR+E + G Y C + N G L
Sbjct: 8450 VVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFA-TLS 8508
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
VL P I + + G L CTV P W+++ L++ + +S
Sbjct: 8509 VLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVS 8568
Query: 317 TLLIADVQPEDFGNYSCVADNSLGR--ARRHVEVSGRPGPARFT 358
L I +V P D G YS N +G+ ++VS R P FT
Sbjct: 8569 GLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFT 8612
Score = 61.7 bits (143), Expect = 6e-09
Identities = 52/210 (24%), Positives = 84/210 (40%), Gaps = 12/210 (5%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
+ + DAG+Y C++++ V V + PPS E+ ++ RGG A + G
Sbjct: 5381 KFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIES--TSSLRGGTAAFQATLKG 5438
Query: 201 NPVPTVTWHR-----LNDSSSRL---GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
+ TVTW + D + R+ L LS +E H G Y C N G +
Sbjct: 5439 SLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSA 5498
Query: 253 FQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
L V P IT E + +G A L W+++ L+ + +S
Sbjct: 5499 L-LSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVT 5557
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+ L I + +D G Y+ N +GR+
Sbjct: 5558 DTVSILKIISTEKKDSGEYTFEVQNDVGRS 5587
Score = 60.1 bits (139), Expect = 2e-08
Identities = 50/212 (23%), Positives = 84/212 (39%), Gaps = 21/212 (9%)
Query: 146 QDAGDYVCQISDRVARDQVHTV----EVLVPPSVRASPETRHVTARRGGAAVLECRAAGN 201
QDAG Y Q+ + V + V + VPPS + ++ G + +LEC+ AG+
Sbjct: 6696 QDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSF--TRRLKNTGGVLGASCILECKVAGS 6753
Query: 202 PVPTVTWHRLNDSSSRLGEGPQ-----------LQLSRLERHHGGVYACTVDNGVGPPVV 250
+V W +++ G + LQL+ L+ G Y C N G
Sbjct: 6754 SPISVAWFH---EKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDEC 6810
Query: 251 TEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
L V PP E + G + PP +V+W++ + L +R +
Sbjct: 6811 RAV-LTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIY 6869
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+ L + ++ G Y+CV N+ G+A
Sbjct: 6870 FEDTVAELELFNIDISQSGEYTCVVSNNAGQA 6901
Score = 59.7 bits (138), Expect = 2e-08
Identities = 56/228 (24%), Positives = 91/228 (39%), Gaps = 15/228 (6%)
Query: 146 QDAGDYVCQISDRVARDQVHTV-EVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D +Y C++S+ D + V PPS P + A + G P
Sbjct: 6229 EDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQ--AIPDSTVEFKAILKGTPPF 6286
Query: 205 TVTWHR-----LNDSSSRLG-EGPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
+ W + ++ +G EG L L ++ G Y C V N VG T L
Sbjct: 6287 KIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLL- 6345
Query: 257 VLYPPEIT--VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP+ +E S + G + L C + P V W++N L AS++ M+ S
Sbjct: 6346 VTEPPKFVKKLEASKI-VKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDS 6404
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPL 362
+ + ++ ED G++ C A N G +V + P + PP+
Sbjct: 6405 VAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPI 6452
Score = 58.4 bits (135), Expect = 5e-08
Identities = 45/206 (21%), Positives = 87/206 (42%), Gaps = 10/206 (4%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+D+G+Y+C+ + D ++ V+V S + E + + + +L AG P
Sbjct: 5292 EDSGEYMCEAQNEAGSDHCSSI-VIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFE 5350
Query: 206 VTWHRLND---SSSRLGEGPQ-----LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+TW + N S + Q LQ+ + G Y C V N VG + + ++ +
Sbjct: 5351 ITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSA-RVTL 5409
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP + + G A T+ P V+W ++S ++ + + M+ + +
Sbjct: 5410 REPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVAS 5469
Query: 318 LLIADVQPEDFGNYSCVADNSLGRAR 343
L ++ ++ + G Y C A N G R
Sbjct: 5470 LYLSGIEVKHDGKYVCQAKNDAGIQR 5495
Score = 58.0 bits (134), Expect = 7e-08
Identities = 47/203 (23%), Positives = 82/203 (40%), Gaps = 13/203 (6%)
Query: 149 GDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW 208
G YVCQ + + + + P+ + E + +G A L+ + +G T W
Sbjct: 5481 GKYVCQAKNDAGIQRCSALLSVKEPAT-ITEEAVSIDVTQGDPATLQVKFSGTKEITAKW 5539
Query: 209 HRLNDSSSRLGEGPQ---------LQLSRLERHHGGVYACTVDNGVGPPVVTEF--QLQV 257
+ + LG + L++ E+ G Y V N VG L +
Sbjct: 5540 FK-DGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDL 5598
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
+ PP T + + + +G +L C V P + W+++ +SASE+ S +
Sbjct: 5599 IIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAF 5658
Query: 318 LLIADVQPEDFGNYSCVADNSLG 340
L I+ ++ D G Y+C A N G
Sbjct: 5659 LEISQLEGTDSGTYTCSATNKAG 5681
Score = 57.6 bits (133), Expect = 9e-08
Identities = 52/204 (25%), Positives = 82/204 (40%), Gaps = 12/204 (5%)
Query: 147 DAGDYVCQISDRVARDQVHTV-EVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C ++ D+ V V PPS +P++ V G + G P
Sbjct: 7734 DTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLP--GMSLTFTSVIRGTPPFK 7791
Query: 206 VTWHRLN------DSSSRLGEG--PQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V W + + +S + E +L+L ++ G Y+C V N G T L V
Sbjct: 7792 VKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTT-HLFV 7850
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
P + G L T PP VSW ++ + +S SER +++ +
Sbjct: 7851 KEPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTI 7910
Query: 318 LLIADVQPEDFGNYSCVADNSLGR 341
L I + ED+ YSC+ +N G+
Sbjct: 7911 LEILESTIEDYAQYSCLIENEAGQ 7934
Score = 57.6 bits (133), Expect = 9e-08
Identities = 51/207 (24%), Positives = 80/207 (38%), Gaps = 18/207 (8%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D+GDY C ++ D+ + V PPS P+ V G G P +
Sbjct: 8675 DSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLT--GTNVTFTSIVKGTPPFS 8732
Query: 206 VTWHRLNDSSSRLGEGP-----------QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
V+W + SS L G +L+L ++ G Y C V N G T
Sbjct: 8733 VSWFK---GSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTT-H 8788
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
L + P + + +G L T PP V+W +N ++ S+R ++
Sbjct: 8789 LYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEK 8848
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGR 341
+ L I ED G Y+C +N+ G+
Sbjct: 8849 SAILEIPSSTVEDAGQYNCYIENASGK 8875
Score = 56.0 bits (129), Expect = 3e-07
Identities = 51/202 (25%), Positives = 78/202 (38%), Gaps = 11/202 (5%)
Query: 149 GDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW 208
G Y C +++ A Q E++V + + G A LE AG P W
Sbjct: 4919 GKYTC-LAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKW 4977
Query: 209 HR-----LNDSSSRLG---EGPQLQLSRLERHHGGVYACTVDNGVGPPVV-TEFQ-LQVL 258
++ + R+ QL+ E H G Y + N VG T F L
Sbjct: 4978 YKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRD 5037
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
P T V + L C + P VSW+++ ++AS+R ++ +L
Sbjct: 5038 IAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASL 5097
Query: 319 LIADVQPEDFGNYSCVADNSLG 340
I V D GN++C A NS+G
Sbjct: 5098 EIIRVDMNDAGNFTCRATNSVG 5119
Score = 55.2 bits (127), Expect = 5e-07
Identities = 52/204 (25%), Positives = 75/204 (36%), Gaps = 14/204 (6%)
Query: 149 GDYVCQI---SDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
G+YVC+ S + A TV P ++ E V G A C P
Sbjct: 4356 GEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVAL--GHLAKFTCEIQSAPNVR 4413
Query: 206 VTWHRL------NDSSSRLGEG--PQLQLSRLERHHGGVYACTVDNGVGPPVVTE-FQLQ 256
W + +D S L++ R + G Y C N G T +
Sbjct: 4414 FQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVT 4473
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
YPP + T G A+ +CTV P E W ++ LS S +S + H
Sbjct: 4474 EAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWKISDAENKH 4533
Query: 317 TLLIADVQPEDFGNYSCVADNSLG 340
L ++++ +D G YSC A N G
Sbjct: 4534 ILELSNLTIQDRGVYSCKASNKFG 4557
Score = 55.2 bits (127), Expect = 5e-07
Identities = 53/204 (25%), Positives = 80/204 (39%), Gaps = 12/204 (5%)
Query: 146 QDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D+G Y C+ + V D T + + PPS + E + RG A+L+C +G
Sbjct: 4730 EDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIV--RGTNALLQCEVSGTGPF 4787
Query: 205 TVTWHRLND---SSSRLGEGPQLQLSRLE-----RHHGGVYACTVDNGVGPPVVTEFQLQ 256
++W + SS + Q L LE G Y C V N VG L
Sbjct: 4788 EISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHL- 4846
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
+ PP + + G L V P V+W + + ++ MS
Sbjct: 4847 LKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVA 4906
Query: 317 TLLIADVQPEDFGNYSCVADNSLG 340
L+I DVQ G Y+C+A+N G
Sbjct: 4907 VLIIPDVQISFGGKYTCLAENEAG 4930
Score = 54.8 bits (126), Expect = 7e-07
Identities = 44/210 (20%), Positives = 91/210 (43%), Gaps = 17/210 (8%)
Query: 146 QDAGDYVCQISDRVARD----QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGN 201
+D+G+Y ++ + V R +++ +++++PPS + + + + + +G LEC AG+
Sbjct: 5571 KDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSF--TKKLKKMDSIKGSFIDLECIVAGS 5628
Query: 202 PVPTVTWHRLNDSSSRLGEGPQ---------LQLSRLERHHGGVYACTVDNGVGPPVVTE 252
++ W + +D E + L++S+LE G Y C+ N G +
Sbjct: 5629 HPISIQWFK-DDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSG 5687
Query: 253 FQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
L V PP + R +L V P + W++++ L + ++
Sbjct: 5688 -HLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKD 5746
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
++ +L + + D G Y C N +G A
Sbjct: 5747 DTSTSLELFAAKATDSGTYICQLSNDVGTA 5776
Score = 54.4 bits (125), Expect = 9e-07
Identities = 46/217 (21%), Positives = 83/217 (38%), Gaps = 9/217 (4%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+G Y C++S+ + + P+ ++G A L C+ G P +
Sbjct: 5199 DSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKI 5258
Query: 207 TW----HRLNDSS----SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
TW + +SS S + L+L+ + G Y C N G + + V
Sbjct: 5259 TWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVI-VK 5317
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
P T E + + + L+ V PP E++W++++ L + + + +L
Sbjct: 5318 ESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSL 5377
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
I D G Y C N +G + V+ R P+
Sbjct: 5378 QILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPS 5414
Score = 53.6 bits (123), Expect = 2e-06
Identities = 51/205 (24%), Positives = 77/205 (37%), Gaps = 13/205 (6%)
Query: 146 QDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D+GDY+C+ + V T + V PP P V A +G +L+C +G P
Sbjct: 7357 EDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSP--VGALKGSDVILQCEISGTPPF 7414
Query: 205 TVTWHR-----LNDSSSRLGE---GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
V W + N ++ L + LE G Y C N VG + ++
Sbjct: 7415 EVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCS-CSVK 7473
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQN-SFPLSASERVTMSARGSN 315
PP + S T G EL V P V W ++ + SE +S +
Sbjct: 7474 FKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNI 7533
Query: 316 HTLLIADVQPEDFGNYSCVADNSLG 340
TL + + + G Y C N G
Sbjct: 7534 ATLQLGSPEASNSGKYICQIKNDAG 7558
Score = 50.8 bits (116), Expect = 1e-05
Identities = 65/245 (26%), Positives = 96/245 (39%), Gaps = 23/245 (9%)
Query: 130 RITSEQHGNTNFRMI---FQDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVT 185
+ITS+ H +T+ ++ D G+Y C+ ++ V D +V+ PP R + +
Sbjct: 7432 KITSK-HFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPP--RFVKKLSDTS 7488
Query: 186 ARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQ---------LQLSRLERHHGGV 236
G A L G +V W + R E + LQL E + G
Sbjct: 7489 TLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGK 7548
Query: 237 YACTVDNGVGPPVVTEFQLQVLYPPEITV--ERSWVHTGEGFRAELVCTVLADPPAEVSW 294
Y C + N G + L VL P I E V TG F E C V P W
Sbjct: 7549 YICQIKNDAGMRECSAV-LTVLEPARIIEKPEPMTVTTGNPFALE--CVVTGTPELSAKW 7605
Query: 295 YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRAR--RHVEVSGRP 352
+++ LSA + ++ +L I + D G YS NS+G++ V VS R
Sbjct: 7606 FKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRI 7665
Query: 353 GPARF 357
P F
Sbjct: 7666 VPPSF 7670
Score = 50.4 bits (115), Expect = 1e-05
Identities = 53/210 (25%), Positives = 80/210 (38%), Gaps = 18/210 (8%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASP----ETRHVTARRGGAAVLECRAAGN 201
+++G YVC+ AR+ T + V+ P E + V + LEC G
Sbjct: 5854 ENSGTYVCE-----ARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGT 5908
Query: 202 PVPTVTWHRLND---SSSRLGEGPQ-----LQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
P VTW + N SS + + L +++ + G Y C V N G
Sbjct: 5909 PPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNE-GGSCSCST 5967
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
++ + PP + T A TV PP ++W ++ L + V +S
Sbjct: 5968 RVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVD 6027
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRAR 343
S TL I V G Y+C A N G R
Sbjct: 6028 SVATLQIRSVDNGHSGRYTCQAKNESGVER 6057
Score = 48.4 bits (110), Expect = 6e-05
Identities = 43/204 (21%), Positives = 77/204 (37%), Gaps = 13/204 (6%)
Query: 148 AGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
+G Y CQ + ++ + +LV + + + V LEC AG P V
Sbjct: 6042 SGRYTCQAKNESGVERCYAF-LLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVK 6100
Query: 208 WHRLND--------SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL- 258
W + S S ++ + + G Y V+N G + L+VL
Sbjct: 6101 WLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAY-LRVLD 6159
Query: 259 --YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
PP T + + + G + C V P W+++ +S S + + +
Sbjct: 6160 QNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSV 6219
Query: 317 TLLIADVQPEDFGNYSCVADNSLG 340
+L + +++ ED NY+C N G
Sbjct: 6220 SLEVNNLELEDTANYTCKVSNVAG 6243
Score = 48.4 bits (110), Expect = 6e-05
Identities = 31/112 (27%), Positives = 53/112 (47%), Gaps = 5/112 (4%)
Query: 245 VGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
+G PV+ + L + ++ + GE + E+ V+ P +SW ++ PL +
Sbjct: 25226 LGVPVIAK-DLTIQPSLKLPFNTYSIQAGEDLKIEI--PVIGRPRPNISWVKDGEPLKQT 25282
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH--VEVSGRPGP 354
RV + ++ L I + +DFG Y+ A NS G A + V V +PGP
Sbjct: 25283 TRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGP 25334
Score = 46.0 bits (104), Expect = 3e-04
Identities = 51/220 (23%), Positives = 82/220 (37%), Gaps = 18/220 (8%)
Query: 149 GDYVCQISDRVARDQVHTVEVL----VPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
G Y C S+ + +L VPP P + V G + +C G
Sbjct: 8111 GQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVS--VDLALGESGTFKCHVTGTAPI 8168
Query: 205 TVTWHRLN-------DSSSRLGEGPQ-LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
+TW + N + L E L + ++ + G Y C N G + L
Sbjct: 8169 KITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSA-HLG 8227
Query: 257 VLYPPEIT--VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
V PP +E S + + F C + P +V WY++ + S + MS S
Sbjct: 8228 VQEPPRFIKKLEPSRIVKQDEF-TRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDS 8286
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
L + ++ ED G+Y+C A N+ G A + + P
Sbjct: 8287 VAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPP 8326
Score = 46.0 bits (104), Expect = 3e-04
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 2/82 (2%)
Query: 275 GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCV 334
G + EL TV P +++W + L +R+T+ T+ I D + D G Y
Sbjct: 14632 GTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIE 14691
Query: 335 ADNSLGRARRHVEVS--GRPGP 354
A N GRA VEV+ +PGP
Sbjct: 14692 AVNVCGRATAVVEVNVLDKPGP 14713
Score = 45.6 bits (103), Expect = 4e-04
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTM--SARGSNHT 317
PP E + +G A TV+ +P V+W++ + L S T+ + GS T
Sbjct: 3620 PPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSG-T 3678
Query: 318 LLIADVQPEDFGNYSCVADNSLGRA 342
++ D Q ED G Y C A+N LG +
Sbjct: 3679 FIVNDPQREDSGLYICKAENMLGES 3703
Score = 45.6 bits (103), Expect = 4e-04
Identities = 47/181 (25%), Positives = 72/181 (39%), Gaps = 22/181 (12%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
E L + P VSW + PL+ RV++ + N TL++ D Q D G Y+
Sbjct: 20923 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTI 20982
Query: 334 VADNSLG--RARRHVEVSGRP----GPARFTSPPLARAPHSYTLSFAVDSYPPLDELRLL 387
N G ++V G+P GP +F + TL +A PP D+
Sbjct: 20983 TLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEV----TAEAMTLKWA----PPKDDGGSE 21034
Query: 388 YRQLAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWN 447
+ + +W V A A + T RV+ G++ Y V A+N+YG
Sbjct: 21035 ITNYILEKRDSVNNKW---VTCASAVQ-KTTFRVTRLHEGME----YTFRVSAENKYGVG 21086
Query: 448 E 448
E
Sbjct: 21087 E 21087
Score = 44.4 bits (100), Expect = 0.001
Identities = 23/75 (30%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 262 EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIA 321
E E + E + EL C +++ E WY N L ++ + T+++R L +
Sbjct: 2268 EFVKELQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVK 2326
Query: 322 DVQPEDFGNYSCVAD 336
DV ED G YS V D
Sbjct: 2327 DVTKEDQGEYSFVID 2341
Score = 44.4 bits (100), Expect = 0.001
Identities = 21/64 (32%), Positives = 33/64 (51%)
Query: 278 AELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADN 337
A L TV+ P ++ W+ N L+ S G +H+L+I + ED G Y+C+A N
Sbjct: 3520 ATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASN 3579
Query: 338 SLGR 341
G+
Sbjct: 3580 DYGK 3583
Score = 44.4 bits (100), Expect = 0.001
Identities = 36/145 (24%), Positives = 61/145 (42%), Gaps = 11/145 (7%)
Query: 237 YACTVDNGVGPP--VVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSW 294
YAC V++ V E ++++ PP+ +E F AEL EV W
Sbjct: 13819 YACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVV--FLAEL-----NKDKVEVQW 13871
Query: 295 YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
+N+ + ++ M + G H L I D++P D G Y +A + RA+ +E++ P
Sbjct: 13872 LRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAK--LELAAAPKI 13929
Query: 355 ARFTSPPLARAPHSYTLSFAVDSYP 379
+ T+ D+YP
Sbjct: 13930 KTADQDLVVDVGKPLTMVVPYDAYP 13954
Score = 44.4 bits (100), Expect = 0.001
Identities = 60/268 (22%), Positives = 104/268 (38%), Gaps = 26/268 (9%)
Query: 189 GGAAVLECRAAGNPVPTVTWHRLNDSSSRLG--EGPQLQLSRLERHHGGVYACTVDNGVG 246
GG+ ++ +P W R N + ++ E L ++ A T N +
Sbjct: 20144 GGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVN-IS 20202
Query: 247 PPVVTEFQLQVL---YPPEITVE---RSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFP 300
PP + +L PP I + +S + G L TV P VSW ++
Sbjct: 20203 PPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTL 20262
Query: 301 LSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG--RARRHVEVSGRPGPARFT 358
L +E + M+ + + TL + V +D G+Y+ A+NS G A ++V +PGP
Sbjct: 20263 LKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGP---- 20318
Query: 359 SPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAAPAAKGSLT 418
P + Y+ + PPL++ +++ W V P S+
Sbjct: 20319 -PASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVE 20377
Query: 419 HRV-SHELRGLQPAAVYEAIVQAKNRYG 445
+ HE Y+ + A+N+YG
Sbjct: 20378 KLIEGHE---------YQFRICAENKYG 20396
Score = 43.6 bits (98), Expect = 0.002
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 270 VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFG 329
V GE + ++ + P V+W++++ PL + RV + +N L I D ED G
Sbjct: 23086 VLAGEDLKVDV--PFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVG 23143
Query: 330 NYSCVADNSLGRA--RRHVEVSGRPGP 354
+Y NS G A +V V +PGP
Sbjct: 23144 HYVVKLTNSAGEAIETLNVIVLDKPGP 23170
Score = 42.7 bits (96), Expect = 0.003
Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I +E + EG + + A P VSW+++ + AS+R+TM + L +
Sbjct: 15314 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 15373
Query: 321 ADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPAR 356
D G Y+ +N LG A +V+V G PGP +
Sbjct: 15374 PKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCK 15411
Score = 42.3 bits (95), Expect = 0.004
Identities = 26/94 (27%), Positives = 41/94 (43%)
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
+L ++ P VE T F + L+ A V WY+N + ++ G
Sbjct: 13742 ELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDG 13801
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE 347
S H L+I D + +D Y+C ++ RAR VE
Sbjct: 13802 SIHRLIIKDCRLDDECEYACGVEDRKSRARLFVE 13835
Score = 41.1 bits (92), Expect = 0.009
Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 4/107 (3%)
Query: 250 VTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTM 309
V E + Q+L P + E+ + G+ R E V P W + + S + +
Sbjct: 19817 VYEAKEQLLPPKILMPEQITIKAGKKLRIE--AHVYGKPHPTCKWKKGEDEVVTSSHLAV 19874
Query: 310 SARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE--VSGRPGP 354
S+ L+I DV +D G YS A+NS G + ++ V PGP
Sbjct: 19875 HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGP 19921
Score = 40.7 bits (91), Expect = 0.012
Identities = 18/56 (32%), Positives = 30/56 (53%)
Query: 288 PPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRAR 343
P ++SWY+ + L S++ +S G HTL + + Q +D GNY V + A+
Sbjct: 9611 PEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVCGPHIASAK 9666
Score = 40.7 bits (91), Expect = 0.012
Identities = 26/97 (26%), Positives = 44/97 (45%), Gaps = 5/97 (5%)
Query: 237 YACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ 296
Y+C V ++T + + ++ T + + E +LVC V + P AEV WY+
Sbjct: 13370 YSCEVRTARTSGMLTVLEEEAVF----TKNLANIEVSETDTIKLVCEV-SKPGAEVIWYK 13424
Query: 297 NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
+ + R + G L+I + ED GNY+C
Sbjct: 13425 GDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNC 13461
Score = 40.7 bits (91), Expect = 0.012
Identities = 35/137 (25%), Positives = 53/137 (38%), Gaps = 14/137 (10%)
Query: 162 DQVHTVEVLVPPSVRASPETR-HVTARRGGAAVLECRAAGNPVPTVTWHR--------LN 212
+ V ++L P + R V A+ G + G P PTVTW +
Sbjct: 28185 EPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDAR 28244
Query: 213 DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHT 272
S L + ++ R+ G Y T++NGVG P + ++VL P + H
Sbjct: 28245 YSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHV 28304
Query: 273 GEGFRAELVCTVLADPP 289
G T+L DPP
Sbjct: 28305 SRG-----TVTLLWDPP 28316
Score = 40.3 bits (90), Expect = 0.015
Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 251 TEFQLQVLYPP-EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTM 309
T L V PP E T EG A L C V + A+V W++N + S++ +
Sbjct: 13201 THANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSREN-AKVKWFKNGTEILKSKKYEI 13259
Query: 310 SARGSNHTLLIADVQPEDFGNYSCVA 335
A G L+I D PED Y+C A
Sbjct: 13260 VADGRVRKLVIHDCTPEDIKTYTCDA 13285
Score = 40.3 bits (90), Expect = 0.015
Identities = 50/220 (22%), Positives = 82/220 (37%), Gaps = 23/220 (10%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D +Y C + DR +R ++ E+ P + P+ GA V+ V
Sbjct: 13815 DECEYACGVEDRKSRARLFVEEI--PVEIIRPPQD---ILEAPGADVVFLAELNKDKVEV 13869
Query: 207 TWHRLN------DSSSRLGEGP--QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W R N D + EG +LQ+ ++ G Y + +L++
Sbjct: 13870 QWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRF-----IAKDKEARAKLELA 13924
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
P+I + G +V A P AE W++ + PLS T+ +
Sbjct: 13925 AAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK---TIDTTAEQTSF 13981
Query: 319 LIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPAR 356
I + + D G Y V N G+A +++V PGP R
Sbjct: 13982 RILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVR 14021
Score = 40.3 bits (90), Expect = 0.015
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 9/102 (8%)
Query: 260 PPEITVERSW-----VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
PP I+++ + VH GE F+ + + P + W + LS + R+ + +
Sbjct: 23467 PPRISMDPKYKDTIVVHAGESFKVD--ADIYGKPIPTIQWIKGDQELSNTARLEIKSTDF 23524
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGR--ARRHVEVSGRPGP 354
+L + D D GNY A N G +V+V RPGP
Sbjct: 23525 ATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP 23566
Score = 39.9 bits (89), Expect = 0.020
Identities = 43/166 (25%), Positives = 65/166 (39%), Gaps = 15/166 (9%)
Query: 288 PPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE 347
P A V+W ++ L + RV +S+ + +L I + ED G Y NS G +
Sbjct: 26349 PQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPIT 26408
Query: 348 --VSGRPGPARFTSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHD 405
V RPGP P R S + PP + + + WH
Sbjct: 26409 IIVLDRPGP-----PGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWH- 26462
Query: 406 VVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVSD 451
+V A A R S ++ L + Y+ V A+NRYG + S+
Sbjct: 26463 IVSQAVA-------RTSIKIVRLTTGSEYQFRVCAENRYGKSSYSE 26501
Score = 39.5 bits (88), Expect = 0.027
Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 8/112 (7%)
Query: 248 PVVTEFQLQVLYPPEITVERSWVHT---GEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
PV+ + QL+ PPEI ++ HT G ++ + P +V+ ++ PL A+
Sbjct: 27391 PVLIKEQLE---PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKAT 27447
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG--RARRHVEVSGRPGP 354
R N T+ + + D G Y A NS G +A ++ V RPGP
Sbjct: 27448 MRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGP 27499
Score = 39.1 bits (87), Expect = 0.035
Identities = 31/120 (25%), Positives = 49/120 (40%), Gaps = 5/120 (4%)
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
G ++ R E HG T V PV ++ V PP + V EG L
Sbjct: 908 GTTVREERFEVLHGREAKVTETARVPAPV----EIPVT-PPTLVSGLKNVTVIEGESVTL 962
Query: 281 VCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
C + P V+WY+ + + +S ++ + L+I + ED G ++C A N G
Sbjct: 963 ECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAG 1022
Score = 39.1 bits (87), Expect = 0.035
Identities = 42/172 (24%), Positives = 68/172 (39%), Gaps = 12/172 (6%)
Query: 193 VLECRAAGNPVPTVTWHRLN-DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVT 251
V+EC+ G T W+R+N D R L + + A + P +
Sbjct: 18766 VVECQKPG----TAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELA 18821
Query: 252 EFQL--QVLYPPEITVE---RSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASER 306
E + +L+PPE+ ++ R + G ++ V P +++W + L +R
Sbjct: 18822 ESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR 18881
Query: 307 VTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH--VEVSGRPGPAR 356
V + L I + D G Y A NS G A+ V V RPGP +
Sbjct: 18882 VDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQ 18933
Score = 38.7 bits (86), Expect = 0.047
Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHR 210
VE+ V P S ++VT G + LEC +G P PTVTW+R
Sbjct: 936 VEIPVTPPTLVSG-LKNVTVIEGESVTLECHISGYPSPTVTWYR 978
Score = 38.7 bits (86), Expect = 0.047
Identities = 32/113 (28%), Positives = 49/113 (43%), Gaps = 8/113 (7%)
Query: 273 GEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYS 332
GE FR E V PP + W ++ L + ++ + + L+ D D G Y+
Sbjct: 22403 GEAFRLE--ADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYT 22460
Query: 333 CVADNSLGRARR--HVEVSGRPGPARFTSPPLARAPHSYTLSFAVDSYPPLDE 383
A N G A+ +V+V RPGP PLA + + +PPLD+
Sbjct: 22461 LTATNPGGFAKHIFNVKVLDRPGP---PEGPLA-VTEVTSEKCVLSWFPPLDD 22509
Score = 38.7 bits (86), Expect = 0.047
Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 6/89 (6%)
Query: 275 GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCV 334
G L P +SW ++ PL SE V S + TL I + + E G Y+ +
Sbjct: 28505 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 28564
Query: 335 ADNSLGRARRHVEV--SGRP----GPARF 357
DN++ R + V G P GP RF
Sbjct: 28565 LDNAVCRIAVPITVITLGPPSKPKGPIRF 28593
Score = 38.3 bits (85), Expect = 0.062
Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
Query: 277 RAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVAD 336
RA C V ++P V W ++ L ++R+ + H LLI + D G Y+ VA
Sbjct: 3074 RAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAG 3132
Query: 337 NSLGRARRHVE 347
++ A+ VE
Sbjct: 3133 GNVSTAKLFVE 3143
Score = 37.9 bits (84), Expect = 0.082
Identities = 21/69 (30%), Positives = 30/69 (43%), Gaps = 4/69 (5%)
Query: 292 VSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR 351
V WY L S++V + G HTL + DV+ ED G A + + H + +
Sbjct: 13153 VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD----FKTHANLFVK 13208
Query: 352 PGPARFTSP 360
P FT P
Sbjct: 13209 EPPVEFTKP 13217
Score = 37.9 bits (84), Expect = 0.082
Identities = 52/202 (25%), Positives = 83/202 (41%), Gaps = 23/202 (11%)
Query: 258 LYPPEITVE---RSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
L PP + ++ + + GE F L P +VSW+++ + +R + +
Sbjct: 17742 LAPPTLHLDFRDKLTIRVGEAFA--LTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPA 17799
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTSPPLARAPHSYTLS 372
L + D G Y V +NS G + V V RPGP P + T
Sbjct: 17800 TLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGP-----PVGPVSFDEVTKD 17854
Query: 373 FAVDSY-PPLDELRLLYRQLAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPA 431
+ V S+ PPLD+ I + ++ G+ DV + +A T +VS L G
Sbjct: 17855 YMVISWKPPLDDGGSKITNYIIEK--KEVGK--DVWMPVTSASAKTTCKVSKLLEGKD-- 17908
Query: 432 AVYEAIVQAKNRYGWNE--VSD 451
Y + A+N YG ++ VSD
Sbjct: 17909 --YIFRIHAENLYGISDPLVSD 17928
Score = 37.1 bits (82), Expect = 0.14
Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 1/88 (1%)
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P+I + V EG A C V P +V+WY N + S+R + G H L I
Sbjct: 1841 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGI-HYLDI 1899
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEV 348
D + D G A+N G V++
Sbjct: 1900 VDCKSYDTGEVKVTAENPEGVIEHKVKL 1927
Score = 37.1 bits (82), Expect = 0.14
Identities = 20/77 (25%), Positives = 31/77 (40%)
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
+Y ++ V+ EG +A L C V V WY N + +RV +G+
Sbjct: 2442 VYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQR 2501
Query: 318 LLIADVQPEDFGNYSCV 334
L+I D G Y +
Sbjct: 2502 LVINRTHASDEGPYKLI 2518
Score = 37.1 bits (82), Expect = 0.14
Identities = 33/128 (25%), Positives = 55/128 (42%), Gaps = 8/128 (6%)
Query: 223 QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP-EITVERSWVHTGEGFRAELV 281
+L ++ + G Y C ++ + T +L++ P + T + E A
Sbjct: 9727 KLTIADVRAEDQGQYTCKYED-----LETSAELRIEAEPIQFTKRIQNIVVSEHQSATFE 9781
Query: 282 CTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVAD-NSLG 340
C V D A V+WY+ L+ S++ G H + I +V P+D G YS +A G
Sbjct: 9782 CEVSFDD-AIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRG 9840
Query: 341 RARRHVEV 348
AR E+
Sbjct: 9841 EARSTAEL 9848
Score = 36.7 bits (81), Expect = 0.19
Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Query: 252 EFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL--SASERVTM 309
E QL+ LY P ++ EG A V+ P E W+ + + + +V +
Sbjct: 1448 ESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVI 1507
Query: 310 SARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
G+ +L+I P D G ++ VA N GR+
Sbjct: 1508 KEDGTQ-SLIIVPATPSDSGEWTVVAQNRAGRS 1539
Score = 36.7 bits (81), Expect = 0.19
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 9/100 (9%)
Query: 155 ISDRVARDQVHTVEVLVPPSVRASP-ETRHVTARRGGAAVLECRAAGNPVPTVTWHR--- 210
+SD V + E+++ P V S VT R G LE G P P+++W +
Sbjct: 28470 LSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGL 28529
Query: 211 -LNDSS----SRLGEGPQLQLSRLERHHGGVYACTVDNGV 245
L +S S+ L + ++ HGG Y +DN V
Sbjct: 28530 PLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAV 28569
Score = 36.3 bits (80), Expect = 0.25
Identities = 21/69 (30%), Positives = 31/69 (44%), Gaps = 2/69 (2%)
Query: 288 PPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE 347
P +V+W L ++RV+++ TL + D D G Y +N+ G V
Sbjct: 29602 PAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVT 29661
Query: 348 --VSGRPGP 354
V GRPGP
Sbjct: 29662 VVVIGRPGP 29670
Score = 35.9 bits (79), Expect = 0.33
Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
EG + C + P + W++N L R H L IADV+ ED G Y+C
Sbjct: 9685 EGQTCTMTCQ-FSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTC 9743
Query: 334 VADNSLGRARRHVEVSGRPGPARFT 358
++ A +E P +FT
Sbjct: 9744 KYEDLETSAELRIEAE----PIQFT 9764
Score = 35.5 bits (78), Expect = 0.44
Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
EG +AE VC++ + V W ++ L + ++ + A G L++ D +D G Y
Sbjct: 13492 EGEKAEFVCSISKES-FPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTY-- 13548
Query: 334 VADNSLGRARRHVEV 348
V RA H+ V
Sbjct: 13549 VVMVGAARAAAHLTV 13563
Score = 35.5 bits (78), Expect = 0.44
Identities = 33/124 (26%), Positives = 47/124 (37%), Gaps = 8/124 (6%)
Query: 244 GVGPPVVTE--FQLQVLYPPEITVE---RSWVHTGEGFRAELVCTVLADPPAEVSWYQNS 298
G GPP T+ + PP + ++ + + G + V P W +
Sbjct: 16010 GEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEE 16069
Query: 299 FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGR--ARRHVEVSGRPGPAR 356
L +RV + G+ L+I D +D G Y A NS G A VEV PGP
Sbjct: 16070 GELD-KDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVL 16128
Query: 357 FTSP 360
P
Sbjct: 16129 DLKP 16132
Score = 35.5 bits (78), Expect = 0.44
Identities = 40/178 (22%), Positives = 71/178 (39%), Gaps = 16/178 (8%)
Query: 270 VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFG 329
V G+ + E+ + P ++W ++ PL + R+ ++ TL I + +D G
Sbjct: 24168 VQVGQDLKIEV--PISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGG 24225
Query: 330 NYSCVADNSLGRARRHVEV--SGRPGPARFTSPPLARAPHSYTLSFAVDSYPPLDELRLL 387
Y N +G+ +E+ +P P + + S TLS+ PPL
Sbjct: 24226 QYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSW----NPPLYTGGCQ 24281
Query: 388 YRQLAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYG 445
+ + W DVV A A R + ++ L+ Y+ + A+NRYG
Sbjct: 24282 ITNYIVQKRDTTTTVW-DVVSATVA-------RTTLKVTKLKTGTEYQFRIFAENRYG 24331
Score = 35.1 bits (77), Expect = 0.58
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 1/70 (1%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS-ARGSNHTLLIADVQPEDFGNYS 332
EG C + P +++WY++ + ER M + +L I V PED G Y+
Sbjct: 1304 EGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYT 1363
Query: 333 CVADNSLGRA 342
A N G A
Sbjct: 1364 AFASNIKGNA 1373
Score = 35.1 bits (77), Expect = 0.58
Identities = 26/106 (24%), Positives = 45/106 (42%), Gaps = 6/106 (5%)
Query: 244 GVGPPVVTEFQLQ---VLYPPEITVE---RSWVHTGEGFRAELVCTVLADPPAEVSWYQN 297
G G P+ +Q +L PEI ++ R+ V G +++ PP V+W ++
Sbjct: 28176 GQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKD 28235
Query: 298 SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRAR 343
L + R ++ S+ L I V D G Y +N +G +
Sbjct: 28236 EKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPK 28281
Score = 34.7 bits (76), Expect = 0.76
Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 1/74 (1%)
Query: 273 GEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN-HTLLIADVQPEDFGNY 331
G+G A V+ P E WY+N + S+R+ N L+I DV ED +
Sbjct: 2090 GQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASI 2149
Query: 332 SCVADNSLGRARRH 345
A N G H
Sbjct: 2150 MVKAINIAGETSSH 2163
Score = 34.7 bits (76), Expect = 0.76
Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Query: 283 TVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
++L P + SW + + S+ +++ ++ L I +D G Y+ A N G
Sbjct: 21329 SILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTK 21388
Query: 343 RRHVEVS-----GRPGPARFTSPPLARAPHSYT 370
HV+V+ G PGP ++ +A ++T
Sbjct: 21389 VEHVKVTVLDVPGPPGPVEISNVSAEKATLTWT 21421
Score = 34.7 bits (76), Expect = 0.76
Identities = 40/173 (23%), Positives = 68/173 (39%), Gaps = 12/173 (6%)
Query: 273 GEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYS 332
G+ + E+ VL P V+W + L ++RV ++ L I + D G Y
Sbjct: 22007 GDNIKVEI--PVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYP 22064
Query: 333 CVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLA 392
A N +G + + P T P S ++F+ D PP ++ +
Sbjct: 22065 LTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWD--PPENDGGVPISNYV 22122
Query: 393 INESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYG 445
+ W V LA + T++ + GL+ Y+ V+A+NRYG
Sbjct: 22123 VEMRQTDSTTW--VELATTVIR--TTYKATRLTTGLE----YQFRVKAQNRYG 22167
Score = 33.9 bits (74), Expect = 1.3
Identities = 29/110 (26%), Positives = 48/110 (43%), Gaps = 12/110 (10%)
Query: 162 DQVHTVEVLVPPSVRASPETRHV-TARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGE 220
D V + VPP + S + + T + G L+ G P+PTV+W + + + + E
Sbjct: 20209 DPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKK-DGTLLKPAE 20267
Query: 221 GPQLQLSR---------LERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP 261
G ++ + R + R G Y T +N G T +L+VL P
Sbjct: 20268 GIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSAT-IKLKVLDKP 20316
Score = 33.5 bits (73), Expect = 1.8
Identities = 46/193 (23%), Positives = 73/193 (37%), Gaps = 23/193 (11%)
Query: 263 ITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSF----PLSASE--RVTMSARGSNH 316
++V + G + V P ++ W +N P A + + +S +
Sbjct: 16328 LSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKT 16387
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTSPPLARAPHSYTLSFA 374
L I ED G Y+ A N LG R HVEV RP P R + +A Y A
Sbjct: 16388 ELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDA 16447
Query: 375 VDSYPPLDE--LRLLYRQLAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAA 432
PLD + + + ++ ++ W +V A + + + L P
Sbjct: 16448 -----PLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKR--------YGIWKLIPNG 16494
Query: 433 VYEAIVQAKNRYG 445
YE V+A N+YG
Sbjct: 16495 QYEFRVRAVNKYG 16507
Score = 33.5 bits (73), Expect = 1.8
Identities = 22/90 (24%), Positives = 41/90 (45%), Gaps = 4/90 (4%)
Query: 121 HTNVWETTRRITS-EQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASP 179
+TN+ ET +T + FR+ ++A D V + S+ + + + PP V
Sbjct: 26663 YTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTG--PIIVKDDVEPPRVMMDV 26720
Query: 180 ETRHVTARRGGAAV-LECRAAGNPVPTVTW 208
+ R V + G + + AG P+P ++W
Sbjct: 26721 KFRDVIVVKAGEVLKINADIAGRPLPVISW 26750
Score = 32.7 bits (71), Expect = 3.1
Identities = 15/39 (38%), Positives = 22/39 (56%)
Query: 294 WYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYS 332
W ++ + S+RV + +H LLI D+ ED GNYS
Sbjct: 2388 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYS 2426
Score = 32.7 bits (71), Expect = 3.1
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPED 327
EG A VC L+ V W++N L S V +S+ G H L + +V +D
Sbjct: 12514 EGETATFVCE-LSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDD 12566
Score = 32.7 bits (71), Expect = 3.1
Identities = 22/93 (23%), Positives = 37/93 (39%), Gaps = 9/93 (9%)
Query: 162 DQVHTVEVLVPPSVRASPETR-HVTARRGGAAVLECRAAGNPVPTVTWHRLNDSS----- 215
D + + LV P ++ R + GG + +G P PTVTW+ +N+ +
Sbjct: 17438 DVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWN-MNERTLPQEA 17496
Query: 216 --SRLGEGPQLQLSRLERHHGGVYACTVDNGVG 246
+ + +R H GVY+ N G
Sbjct: 17497 TIETTAISSSMVIKNCQRSHQGVYSLLAKNEAG 17529
Score = 32.7 bits (71), Expect = 3.1
Identities = 25/98 (25%), Positives = 39/98 (39%), Gaps = 8/98 (8%)
Query: 161 RDQVHTVEVLVPPSVRASPETRHVTARRGGAAV-LECRAAGNPVPTVTWHRLN-DSSSRL 218
++ + E+L PP + R + R G + L G P P VTW ++ D+ R
Sbjct: 19519 KEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRK 19578
Query: 219 GEGPQ------LQLSRLERHHGGVYACTVDNGVGPPVV 250
G+ L + R G Y+ T+ N G V
Sbjct: 19579 GQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAV 19616
Score = 32.7 bits (71), Expect = 3.1
Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 162 DQVHTVEVLVPPSVRASPETRHVTARRGGAAV-LECRAAGNPVPTVTWHRLN-DSSSRLG 219
D+ + ++L+PP + R R G + L G P P +TW + N + R+G
Sbjct: 20607 DKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG 20666
Query: 220 EGPQ-------LQLSRLERHHGGVYACTVDNGVG 246
+ L+ + ++ G Y T++N G
Sbjct: 20667 LDIKSTDFDTFLRCENVNKYDAGKYILTLENSCG 20700
Score = 32.7 bits (71), Expect = 3.1
Identities = 22/84 (26%), Positives = 36/84 (42%), Gaps = 7/84 (8%)
Query: 170 LVPPSVRASPETRH-VTARRGGAAVLECRAAGNPVPTVTWHRLNDSSS---RLGEG---P 222
L P + E R + R GG+A + G P P +TW R + ++ +G
Sbjct: 24946 LEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYT 25005
Query: 223 QLQLSRLERHHGGVYACTVDNGVG 246
QL + +R+ G Y ++N G
Sbjct: 25006 QLSIDNCDRNDAGKYILKLENSSG 25029
Score = 32.7 bits (71), Expect = 3.1
Identities = 26/105 (24%), Positives = 42/105 (40%), Gaps = 8/105 (7%)
Query: 164 VHTVEVLVPPSVRASPETRHVTARRGGAAV-LECRAAGNPVPTVTWHRLNDSSSRLGE-- 220
+ V+ L P + + R GA++ L G P PT W + + + S +
Sbjct: 29273 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIH 29332
Query: 221 ----GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP 261
L + R+ G Y TV+N G +T F ++VL P
Sbjct: 29333 TTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSIT-FTVKVLDTP 29376
Score = 32.3 bits (70), Expect = 4.1
Identities = 15/71 (21%), Positives = 32/71 (45%), Gaps = 4/71 (5%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASP----ETRHVTARRGGAAVLECRAAGNP 202
D+G++ +R R + + + + P + ++V + G ++ RA GNP
Sbjct: 1524 DSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLEMKVRATGNP 1583
Query: 203 VPTVTWHRLND 213
P + W + +D
Sbjct: 1584 NPDIVWLKNSD 1594
Score = 32.3 bits (70), Expect = 4.1
Identities = 13/56 (23%), Positives = 27/56 (48%)
Query: 292 VSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE 347
V W+ + + S++ + + H L++ ++ P D G Y+ V +A+ VE
Sbjct: 2825 VKWFHKNVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLFVE 2880
Score = 32.3 bits (70), Expect = 4.1
Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 9/85 (10%)
Query: 170 LVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHR-----LNDSSSRLGEGP-- 222
L PP++ + +T R G A L R +G P P V+W + L D + + P
Sbjct: 17742 LAPPTLHLDFRDK-LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPAT 17800
Query: 223 -QLQLSRLERHHGGVYACTVDNGVG 246
L+ + +R G Y V+N G
Sbjct: 17801 LALEKIKAKRSDSGKYCVVVENSTG 17825
Score = 32.3 bits (70), Expect = 4.1
Identities = 32/134 (23%), Positives = 55/134 (41%), Gaps = 11/134 (8%)
Query: 126 ETTRRITSEQHGNT-NFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPE-TRH 183
ET ++T + G T FR++ +A + + V + L PP + R
Sbjct: 18098 ETKYKVTGLRDGQTYKFRVLAVNAAG---ESDPAHVPEPVLVKDRLEPPELILDANMARE 18154
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRLGEGP---QLQLSRLERHHGGVY 237
+ G L G P P VTW + + + +R+ P +L++ GG+Y
Sbjct: 18155 QHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIY 18214
Query: 238 ACTVDNGVGPPVVT 251
+ TV+N G V+
Sbjct: 18215 SLTVENPAGSKTVS 18228
Score = 31.9 bits (69), Expect = 5.4
Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 10/94 (10%)
Query: 122 TNVWETTRRITS-EQHGNTNFRMIFQDAGDYVCQISDRV----ARDQVHTVEVLVPPSVR 176
TNV ET ++ + FR+I ++A + + SD A+D+V + + P R
Sbjct: 24500 TNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFR 24559
Query: 177 ASPETRHVTARRGGAAVLECRAAGNPVPTVTWHR 210
+ + G LE G P+PT+ W R
Sbjct: 24560 DT-----IVVNAGETFRLEADVHGKPLPTIEWLR 24588
Score = 31.5 bits (68), Expect = 7.1
Identities = 13/49 (26%), Positives = 24/49 (48%)
Query: 286 ADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCV 334
++P +V WY++ + ++ M + H L I + D +YSCV
Sbjct: 2199 SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCV 2247
Score = 31.5 bits (68), Expect = 7.1
Identities = 13/44 (29%), Positives = 21/44 (47%)
Query: 294 WYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADN 337
W +N + SE+ + +G H L+I + ED Y+ V N
Sbjct: 2914 WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN 2957
Score = 31.5 bits (68), Expect = 7.1
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 4/87 (4%)
Query: 270 VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFG 329
V+ GE FR E V P + W + + S R + L++ D D G
Sbjct: 24564 VNAGETFRLE--ADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGG 24621
Query: 330 NYSCVADNSLGRAR--RHVEVSGRPGP 354
Y A N G +V+V RPGP
Sbjct: 24622 QYILRASNVAGSKSFPVNVKVLDRPGP 24648
Score = 31.1 bits (67), Expect = 9.4
Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
Query: 25 PRFLSRGHSFRTVVGDTLLLPCQVQNLGSLVLLWRRAPAVLT-AASLMVTRDERFRLVDG 83
P FLSR S T VG C V + +W++ A L+ + + ++ E +++
Sbjct: 4478 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWKISDAENKHILEL 4537
Query: 84 YNLQITDVG 92
NL I D G
Sbjct: 4538 SNLTIQDRG 4546
Score = 31.1 bits (67), Expect = 9.4
Identities = 28/99 (28%), Positives = 41/99 (41%), Gaps = 5/99 (5%)
Query: 254 QLQVLYP-PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
QL+VL P TV+ E L C V D P V W+++ + S + ++ A
Sbjct: 12582 QLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIVPSPKYSIKAD 12639
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR 351
G L I +D G Y C D + + +V V R
Sbjct: 12640 GLRRILKIKKADLKDKGEYVC--DCGTDKTKANVTVEAR 12676
Score = 31.1 bits (67), Expect = 9.4
Identities = 51/228 (22%), Positives = 91/228 (39%), Gaps = 28/228 (12%)
Query: 229 LERHHGGVYACTVDN-GVGP------PVVTEFQLQVLYPPEITVE---RSWVHTGEGFRA 278
LE+H C ++ GVG P++ E +L+ P+I ++ R ++ G
Sbjct: 23831 LEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEA---PDIDLDLELRKIINIRAGGSL 23887
Query: 279 ELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNS 338
L + P EV W + + + + +++ S +L++ +V D G Y+ +NS
Sbjct: 23888 RLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS--SFTSLVLDNVNRYDSGKYTLTLENS 23945
Query: 339 LGRARRHVEVSGRPGPARFTSPPLARAPHSYTL-SFAVDSYPPLDELRLLYRQLAINESF 397
G V V P SPP+ T S ++ PPL + + + +
Sbjct: 23946 SGTKSAFVTVRVLDTP----SPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK-- 23999
Query: 398 QQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYG 445
+ + AA + H+ S ++ LQ Y V A+N YG
Sbjct: 24000 ------REATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYG 24041
Score = 31.1 bits (67), Expect = 9.4
Identities = 37/151 (24%), Positives = 63/151 (41%), Gaps = 14/151 (9%)
Query: 122 TNVWETTRRITS-EQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPE 180
TNV ET ++ + FR+I ++A + SD + + + + P+ P+
Sbjct: 25582 TNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSD--SSGAITARDEIDAPNASLDPK 25639
Query: 181 TRHVTARRGGAA-VLECRAAGNPVPTVTWHR----LNDSSSRLGEGPQLQLSRLE----- 230
+ V G VLE G P+P V W + L ++++R+ +Q + L
Sbjct: 25640 YKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCI 25699
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPP 261
R GG Y + N VG ++VL P
Sbjct: 25700 RTDGGQYILKLSN-VGGTKSIPITVKVLDRP 25729
Score = 31.1 bits (67), Expect = 9.4
Identities = 37/175 (21%), Positives = 68/175 (38%), Gaps = 10/175 (5%)
Query: 189 GGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPP 248
GGA + +P W + N ++ + +L+ +R+ V+A + V P
Sbjct: 26639 GGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEP 26698
Query: 249 VVTEFQLQV---LYPPEITVE---RSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLS 302
+ + V + PP + ++ R + G ++ + P +SW ++ +
Sbjct: 26699 SESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE 26758
Query: 303 ASERVTMSARGSNHTLL-IADVQPEDFGNYSCVADNSLGRARRHV--EVSGRPGP 354
R + + NHTLL + D D G Y N G V +V +PGP
Sbjct: 26759 ERARTEIIST-DNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGP 26812
Score = 31.1 bits (67), Expect = 9.4
Identities = 35/135 (25%), Positives = 54/135 (40%), Gaps = 12/135 (8%)
Query: 122 TNVWETTRRITSEQHGNT-NFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPE 180
T+V E +T G+ FR+I ++A + S + + T + VPP V PE
Sbjct: 28833 TDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQ--SSGIIMTRDENVPPIVEFGPE 28890
Query: 181 TRHVTARRGGAAV-LECRAAGNPVPTVTW--------HRLNDSSSRLGEGPQLQLSRLER 231
+ G ++ ++ G PVP VTW R+N + + L + R
Sbjct: 28891 YFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATR 28950
Query: 232 HHGGVYACTVDNGVG 246
H GVY N G
Sbjct: 28951 DHRGVYTVEAKNASG 28965
>AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion
molecule 1, 120 kDa isoform precursor variant protein.
Length = 807
Score = 82.6 bits (195), Expect = 3e-15
Identities = 82/330 (24%), Positives = 139/330 (42%), Gaps = 34/330 (10%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D +Y+C I++ A +Q T+ + V + + L C A+G+P+P++
Sbjct: 362 DEAEYIC-IAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSI 420
Query: 207 TWH---RLNDSSSRLGEG----------PQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
TW R S + +G L L ++ G Y CT N +G + +
Sbjct: 421 TWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMY 480
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS--FPLSASERVTMSA 311
L+V Y P++ + V+T EG + + C V A P A +SW+++ P S + +
Sbjct: 481 -LEVQYAPKLQGPVA-VYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYN 538
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARA-PHSYT 370
S L + DFGNY+C A N +G+ + P +SP + + P+S T
Sbjct: 539 TPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTP---SSPSIDQVEPYSST 595
Query: 371 LSFAVDSYPPLDELRLL-YRQ--LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRG 427
D + +L Y+ A+ E +W+D A + +G +T + G
Sbjct: 596 AQVQFDEPEATGGVPILKYKAEWRAVGEEVWH-SKWYDAKEA--SMEGIVT------IVG 646
Query: 428 LQPAAVYEAIVQAKNRYGWNEVSDIFQFHT 457
L+P Y + A N G E+S +F T
Sbjct: 647 LKPETTYAVRLAALNGKGLGEISAASEFKT 676
Score = 69.3 bits (162), Expect = 3e-11
Identities = 51/213 (23%), Positives = 94/213 (44%), Gaps = 20/213 (9%)
Query: 147 DAGDYVCQISDRVARDQVH----TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNP 202
D G Y C+ +AR +++ V V VPP+++A + TA G + L C A G P
Sbjct: 264 DEGTYRCE-GRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFP 322
Query: 203 VPTVTWHRLNDSSSR---------LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
PT++W + + + + QL + +++++ Y C +N G T
Sbjct: 323 EPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDAT-I 381
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASER-----VT 308
L+V P+IT + + L C DP ++W ++ +S+ E+ +
Sbjct: 382 HLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMV 441
Query: 309 MSARGSNHTLLIADVQPEDFGNYSCVADNSLGR 341
+ + +L + +Q D G Y C A N++G+
Sbjct: 442 VRSHARVSSLTLKSIQYTDAGEYICTASNTIGQ 474
Score = 46.8 bits (106), Expect = 2e-04
Identities = 52/227 (22%), Positives = 84/227 (37%), Gaps = 13/227 (5%)
Query: 139 TNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRA 198
T + DAG Y C ++ + TV V + + R G AV+ C
Sbjct: 163 TIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDV 222
Query: 199 AGNPVPTVTW-HRLNDSSSR------LGEGPQLQLSRLERHHGGVYACTVD-NGVGPPVV 250
+ PT+ W H+ D + + LQ+ +++ G Y C G
Sbjct: 223 VSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINF 282
Query: 251 TEFQLQVLYPPEITVERSWVH--TGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVT 308
+ Q+ V PP I ++ V+ G LVC P +SW ++ + E
Sbjct: 283 KDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDE 342
Query: 309 MSARGSNHT-LLIADVQPEDFGNYSCVADNSLGR--ARRHVEVSGRP 352
+ + L I V D Y C+A+N G A H++V +P
Sbjct: 343 KYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKP 389
Score = 33.9 bits (74), Expect = 1.3
Identities = 30/134 (22%), Positives = 56/134 (41%), Gaps = 14/134 (10%)
Query: 145 FQDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
+ DAG+Y+C S+ + +D Q +EV P ++ V G + C P
Sbjct: 458 YTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVA---VYTWEGNQVNITCEVFAYPS 514
Query: 204 PTVTWHR-------LNDSSSRLGEGPQ---LQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
T++W R N S+ ++ P L+++ + G Y CT N +G +
Sbjct: 515 ATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFI 574
Query: 254 QLQVLYPPEITVER 267
+Q P ++++
Sbjct: 575 LVQADTPSSPSIDQ 588
>U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion
molecule CD56 protein.
Length = 848
Score = 82.2 bits (194), Expect = 4e-15
Identities = 82/330 (24%), Positives = 139/330 (42%), Gaps = 34/330 (10%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D +Y+C I++ A +Q T+ + V + + L C A+G+P+P++
Sbjct: 281 DEAEYIC-IAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSI 339
Query: 207 TWH---RLNDSSSRLGEG----------PQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
TW R S + +G L L ++ G Y CT N +G + +
Sbjct: 340 TWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMY 399
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS--FPLSASERVTMSA 311
L+V Y P++ + V+T EG + + C V A P A +SW+++ P S + +
Sbjct: 400 -LEVQYAPKLQGPVA-VYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYN 457
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARA-PHSYT 370
S L + DFGNY+C A N +G+ + P +SP + + P+S T
Sbjct: 458 TPSASYLEVTPDSENDFGNYNCTAVNRIGQESFEFILVQADTP---SSPSIDQVEPYSST 514
Query: 371 LSFAVDSYPPLDELRLL-YRQ--LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRG 427
D + +L Y+ A+ E +W+D A + +G +T + G
Sbjct: 515 AQVQFDEPEATGGVPILKYKAEWRAVGEEVWH-SKWYDAKEA--SMEGIVT------IVG 565
Query: 428 LQPAAVYEAIVQAKNRYGWNEVSDIFQFHT 457
L+P Y + A N G E+S +F T
Sbjct: 566 LKPETTYAVRLAALNGKGLGEISAASEFKT 595
Score = 67.7 bits (158), Expect = 9e-11
Identities = 51/213 (23%), Positives = 93/213 (43%), Gaps = 20/213 (9%)
Query: 147 DAGDYVCQISDRVARDQVH----TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNP 202
D G Y C+ +AR +++ V V VPP++RA + TA G + L C A P
Sbjct: 183 DEGTYRCE-GRILARGEINFKDIQVIVNVPPTIRARQNIVNATANLGQSVTLVCDAERFP 241
Query: 203 VPTVTWHRLNDSSSR---------LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
PT++W + + + + QL + +++++ Y C +N G T
Sbjct: 242 EPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDAT-I 300
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASER-----VT 308
L+V P+IT + + L C DP ++W ++ +S+ E+ +
Sbjct: 301 HLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMV 360
Query: 309 MSARGSNHTLLIADVQPEDFGNYSCVADNSLGR 341
+ + +L + +Q D G Y C A N++G+
Sbjct: 361 VRSHARVSSLTLKSIQYTDAGEYICTASNTIGQ 393
Score = 46.4 bits (105), Expect = 2e-04
Identities = 52/227 (22%), Positives = 84/227 (37%), Gaps = 13/227 (5%)
Query: 139 TNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRA 198
T + DAG Y C ++ + TV V + + R G AV+ C
Sbjct: 82 TIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDV 141
Query: 199 AGNPVPTVTW-HRLNDSSSR------LGEGPQLQLSRLERHHGGVYACTVD-NGVGPPVV 250
+ PT+ W H+ D + + LQ+ +++ G Y C G
Sbjct: 142 VSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINF 201
Query: 251 TEFQLQVLYPPEITVERSWVH--TGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVT 308
+ Q+ V PP I ++ V+ G LVC P +SW ++ + E
Sbjct: 202 KDIQVIVNVPPTIRARQNIVNATANLGQSVTLVCDAERFPEPTMSWTKDGEQIEQEEDDE 261
Query: 309 MSARGSNHT-LLIADVQPEDFGNYSCVADNSLGR--ARRHVEVSGRP 352
+ + L I V D Y C+A+N G A H++V +P
Sbjct: 262 KYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKP 308
Score = 33.5 bits (73), Expect = 1.8
Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 14/113 (12%)
Query: 145 FQDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
+ DAG+Y+C S+ + +D Q +EV P ++ V G + C P
Sbjct: 377 YTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVA---VYTWEGNQVNITCEVFAYPS 433
Query: 204 PTVTWHR-------LNDSSSRLGEGPQ---LQLSRLERHHGGVYACTVDNGVG 246
T++W R N S+ ++ P L+++ + G Y CT N +G
Sbjct: 434 ATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIG 486
>AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-specific
heparan sulfate proteoglycan core protein precursor
protein.
Length = 2331
Score = 82.2 bits (194), Expect = 4e-15
Identities = 68/232 (29%), Positives = 89/232 (38%), Gaps = 22/232 (9%)
Query: 147 DAGDYVCQISDRV--ARDQVHTVE---VLVPPSVRASPETRHVTARRGGAAVLECRAAGN 201
DAG YVC + + A+ QV + + P + + E +T G A L C A G+
Sbjct: 1119 DAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGS 1178
Query: 202 PVPTVTWHRLNDS---SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
P PT+ W +L RL EG L + R+ + G Y C + G T L V
Sbjct: 1179 PAPTIHWSKLRSPLPWQYRL-EGDTLIIPRVAQQDSGQYICNATSPAGHAEAT-IILHVE 1236
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ--NSFPLSASERVTMSARGSNH 316
PP T G +L C PP W + +S P A+ R N
Sbjct: 1237 SPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATAR--------NE 1288
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVE--VSGRPGPARFTSPPLARAP 366
L PED G Y C N +G A + V G PG TS P P
Sbjct: 1289 LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTP 1340
Score = 77.0 bits (181), Expect = 1e-13
Identities = 62/223 (27%), Positives = 94/223 (42%), Gaps = 14/223 (6%)
Query: 149 GDYVCQISDRVARDQVHTVEVLVP-PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
G Y+CQ + Q V+ PSV + T T G A EC A G+P P VT
Sbjct: 1402 GTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQVT 1461
Query: 208 WHRLND--SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITV 265
W ++ + G ++++ +E G Y CT N G + L V P+I++
Sbjct: 1462 WSKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAG-TTQSHVLLLVQALPQISM 1520
Query: 266 ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQP 325
+ V G A C P ++SW + L R+ N+ L++ V+P
Sbjct: 1521 PQE-VRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPDSRL------ENNMLMLPSVRP 1573
Query: 326 EDFGNYSCVADNSLGRAR--RHVEVSGRPGPARFTSPPLARAP 366
+D G Y C A N G+ + H++V R P FT P + P
Sbjct: 1574 QDAGTYVCTATNRQGKVKAFAHLQVPERVVP-YFTQTPYSFLP 1615
Score = 69.3 bits (162), Expect = 3e-11
Identities = 58/219 (26%), Positives = 90/219 (41%), Gaps = 20/219 (9%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHV---------TARRGGAAVLECR 197
D+G+YVC+ + +Q + V VPPS +S R T ++G A +C
Sbjct: 925 DSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCL 984
Query: 198 AAGNPVP-TVTW----HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
P ++ W L D+ G + + + G Y C N G +
Sbjct: 985 IHDGAAPISLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGV-AQSV 1043
Query: 253 FQLQVLYPPEITVERS---WVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTM 309
L V PP ++V WV G+ E C +P + W + S + E+ T
Sbjct: 1044 VNLSVHGPPTVSVLPEGPVWVKVGKAVTLE--CVSAGEPRSSARWTRISSTPAKLEQRTY 1101
Query: 310 SARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
S+ L I+ +P D G Y C+A N+LG A++ VEV
Sbjct: 1102 GLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEV 1140
Score = 67.3 bits (157), Expect = 1e-10
Identities = 68/229 (29%), Positives = 93/229 (40%), Gaps = 31/229 (13%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVL-----------VPPS---VRASPETRHVTARRGGA 191
D+G+YVC++ + + TV VL VP S +R P + HV G
Sbjct: 51 DSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVA--EGQT 108
Query: 192 AVLECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP-- 247
L C G VTWH+ S + G L+L ++ G Y C V GP
Sbjct: 109 LDLNCVVPGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLE 168
Query: 248 -PVVTEFQLQVLYPP--EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
V+ + V+ P + +E S EG +L C V A+V+WY+ L A
Sbjct: 169 ASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPAR 228
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
+V RGS L I P D G Y C A N + A V V+G G
Sbjct: 229 HQV----RGSR--LYIFQASPADAGQYVCRASNGM-EASITVTVTGTQG 270
Score = 60.9 bits (141), Expect = 1e-08
Identities = 68/249 (27%), Positives = 96/249 (38%), Gaps = 34/249 (13%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTVEVLVP----PS-------VRASPETRHVTARRGG 190
+M D+G+YVC+ ++ + + V + P PS +R + HV G
Sbjct: 625 QMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVA--EGE 682
Query: 191 AAVLECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP- 247
L C G VTWH+ S S G +L+L + G Y C V GP
Sbjct: 683 TLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPL 742
Query: 248 ---PVVT-----EFQLQVLYP---PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ 296
+VT + V P P I +E S EG +L C V A+V+W++
Sbjct: 743 EASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHK 802
Query: 297 NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRP-GPA 355
L A +V L + V P D G YSC S G V V+ P P
Sbjct: 803 RGGNLPARHQV------HGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPG 856
Query: 356 RFTSPPLAR 364
+P LA+
Sbjct: 857 PIPAPGLAQ 865
Score = 56.8 bits (131), Expect = 2e-07
Identities = 64/250 (25%), Positives = 93/250 (37%), Gaps = 36/250 (14%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVL----------VPPSVRASPETRHVTARRGGAAVLEC 196
D+G+YVC +S+ + + + V P +R E+ T G L C
Sbjct: 534 DSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRI--ESSSPTVVEGQTLDLNC 591
Query: 197 RAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP---PVVT 251
A P +TW++ S S G L+L ++ G Y C +N + +V
Sbjct: 592 VVARQPQAIITWYKRGGSLPSRHQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVI 651
Query: 252 EFQLQVLYPPE------ITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE 305
P I +E S H EG +L C V A+V+W++ L +
Sbjct: 652 SVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHH 711
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV----EVSGRPG---PARFT 358
+ RGS L + V P D G Y C S G V E SG PA
Sbjct: 712 Q----TRGSR--LRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGG 765
Query: 359 SPPLARAPHS 368
+PP+ P S
Sbjct: 766 APPIRIEPSS 775
Score = 55.2 bits (127), Expect = 5e-07
Identities = 72/261 (27%), Positives = 104/261 (39%), Gaps = 38/261 (14%)
Query: 147 DAGDYVCQI---SDRVARDQVHTVE------VLVP-----PSVRASPETRHVTARRGGAA 192
D+G+YVC++ S + + T+E V VP P +R P + V G
Sbjct: 727 DSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVA--EGQTL 784
Query: 193 VLECRAAGNPVPTVTWHRL--NDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP--- 247
L+C G VTWH+ N + GP L+L+++ G Y+C V G
Sbjct: 785 DLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEA 844
Query: 248 PVVTEFQLQVLYP-------PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFP 300
V+ + P I +E S H EG +L C V A+V+WY+
Sbjct: 845 SVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGS 904
Query: 301 LSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG---RARRHVEVSGRPGPA-R 356
L A + GS L + V P D G Y C A + G A V V G + R
Sbjct: 905 LPARHQ----THGSQLRLHL--VSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYR 958
Query: 357 FTSPPLARAPHSYTLSFAVDS 377
SP ++ P S T+ D+
Sbjct: 959 LRSPVISIDPPSSTVQQGQDA 979
Score = 54.4 bits (125), Expect = 9e-07
Identities = 59/237 (24%), Positives = 93/237 (39%), Gaps = 33/237 (13%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASP------------ETRHVTARRGGAAVL 194
D+G+YVC++ V VLV R S E+ + G L
Sbjct: 437 DSGEYVCRV---VGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDL 493
Query: 195 ECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPP---- 248
C A T+TW++ S S G +L++ ++ G Y C V NG G
Sbjct: 494 NCLVASQAPHTITWYKRGGSLPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSL 553
Query: 249 VVT-----EFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA 303
+VT + + PP I +E S EG +L C V P A ++WY+ L +
Sbjct: 554 IVTIQGSGSSHVPSVSPP-IRIESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPS 612
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
+ GS+ L + + D G Y C A+N++ + +S P ++P
Sbjct: 613 RHQ----THGSH--LRLHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAP 663
Score = 54.0 bits (124), Expect = 1e-06
Identities = 58/226 (25%), Positives = 89/226 (39%), Gaps = 28/226 (12%)
Query: 147 DAGDYVCQI---SDRVARDQVHTVEVLVPPSVRA---------SPETRHVTARRGGAAVL 194
D+G+Y CQ+ S + + T+E P + A + HVT G L
Sbjct: 827 DSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVT--EGQTLDL 884
Query: 195 ECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
C G VTW++ S + G QL+L + G Y C +G GP
Sbjct: 885 NCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVCRAASGPGPEQEAS 944
Query: 253 FQLQV---------LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA 303
F + V L P I+++ +G A C ++ D A +S +
Sbjct: 945 FTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKC-LIHDGAAPISLEWKTRNQEL 1003
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+ V +S GS + I +P + G Y CVA N+ G A+ V +S
Sbjct: 1004 EDNVHISPNGS--IITIVGTRPSNHGTYRCVASNAYGVAQSVVNLS 1047
Score = 52.8 bits (121), Expect = 3e-06
Identities = 34/103 (33%), Positives = 47/103 (45%), Gaps = 6/103 (5%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG Y C ++ Q H + ++ + P+ V A G AAV C A+G P P +
Sbjct: 1489 DAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPA--GSAAVFPCIASGYPTPDI 1546
Query: 207 TWHRLNDS---SSRLGEGPQLQLSRLERHHGGVYACTVDNGVG 246
+W +L+ S SRL E L L + G Y CT N G
Sbjct: 1547 SWSKLDGSLPPDSRL-ENNMLMLPSVRPQDAGTYVCTATNRQG 1588
Score = 52.4 bits (120), Expect = 4e-06
Identities = 54/181 (29%), Positives = 73/181 (40%), Gaps = 27/181 (14%)
Query: 194 LECRAAGNPVPTVTWHRLNDSSSRLGE--GPQLQLSRLERHHGGVYACTVDNGVGPPVVT 251
L C AG+ VTW+R S + G +L+L ++ G Y C V+NG GP +
Sbjct: 10 LNCVVAGSAHAQVTWYRRGGSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENGSGPKEAS 69
Query: 252 EFQLQVL--------YPP------EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQN 297
+ VL Y P I +E S H EG +L C V A+V+W++
Sbjct: 70 -ITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKR 128
Query: 298 SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV----EVSGRPG 353
L A + GS L + V P D G Y C + G V E S PG
Sbjct: 129 GGSLPARHQ----THGS--LLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPG 182
Query: 354 P 354
P
Sbjct: 183 P 183
Score = 49.6 bits (113), Expect = 3e-05
Identities = 69/271 (25%), Positives = 93/271 (34%), Gaps = 29/271 (10%)
Query: 102 TIYENSETSVALAILGATGHTNVWETTRRITSEQHGNTNFRM-IFQ----DAGDYVCQIS 156
T+ E ++ + G W +H R+ IFQ DAG YVC+ S
Sbjct: 195 TVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRAS 254
Query: 157 DRVARDQVHTVEV-----LVPPSVRASP---ETRHVTARRGGAAVLECRAAGNPVPTVTW 208
+ + TV L P+ P E G L C G VTW
Sbjct: 255 NGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTW 314
Query: 209 HRLNDSSS--RLGEGPQLQLSRLERHHGGVYACTVDNGVGP---PVVTEFQLQVLYP--- 260
H+ S G L+L + G Y C V P V+ + P
Sbjct: 315 HKRGGSLPVRHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALG 374
Query: 261 --PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
P + +E S EG +L C V A+V+W++ L A +V GS L
Sbjct: 375 VTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQV----HGSRLRL 430
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
L V P D G Y C S G V V+
Sbjct: 431 L--QVTPADSGEYVCRVVGSSGTQEASVLVT 459
Score = 36.3 bits (80), Expect = 0.25
Identities = 24/76 (31%), Positives = 32/76 (42%), Gaps = 6/76 (7%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
EG +L C V A+V+WY+ L +V GS L + V P D G Y C
Sbjct: 4 EGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQV----HGSR--LRLPQVSPADSGEYVC 57
Query: 334 VADNSLGRARRHVEVS 349
+N G + VS
Sbjct: 58 RVENGSGPKEASITVS 73
>BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein.
Length = 617
Score = 81.0 bits (191), Expect = 9e-15
Identities = 52/161 (32%), Positives = 72/161 (44%), Gaps = 9/161 (5%)
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRLGEGPQ-LQLSRLERHHGGVYAC 239
VTA +G +EC A GNPVPT+TW ++N S +RL + L++ ++ G+Y C
Sbjct: 16 VTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQAVLEIPNVQLDDAGIYEC 75
Query: 240 TVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSF 299
+N G QLQV P + + G C P W +N
Sbjct: 76 RAENSRGKNSF-RGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGV 134
Query: 300 PLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
PLS RV M N L+I +V D G Y C+A+N G
Sbjct: 135 PLSPQSRVEM----VNGVLMIHNVNQSDAGMYQCLAENKYG 171
Score = 51.2 bits (117), Expect = 8e-06
Identities = 56/261 (21%), Positives = 104/261 (39%), Gaps = 21/261 (8%)
Query: 147 DAGDYVCQISDRVARDQVHT-VEVLVP-PSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
DAG Y C ++ +++L P+ + + + + V+EC+ G+P P
Sbjct: 158 DAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKP 217
Query: 205 TVTWH------RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVG-PPVVTEFQLQV 257
T++W R N + L +G L++ + G Y C +N G ++ ++
Sbjct: 218 TISWKKGDRAVRENKRIAILPDG-SLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKE 276
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS--WYQNSFPLSASER----VTMSA 311
E+T +R+ + GE L C + D +V+ W P+ E ++ A
Sbjct: 277 PTRIELTPKRTELTVGESI--VLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRA 334
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE--VSGRPGPARFT-SPPLARAPHS 368
+ S+ L+I ++ G Y C + E V G PGP + + +
Sbjct: 335 QASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITESTAT 394
Query: 369 YTLSFAVDSYPPLDELRLLYR 389
+ S A D++ P+ L R
Sbjct: 395 LSWSPAADNHSPISSYNLQAR 415
Score = 38.7 bits (86), Expect = 0.047
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 5/84 (5%)
Query: 259 YPPEITVERSWVHTG-EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
Y P+I V + T +G ++ C L +P ++W + + + + R+ R S
Sbjct: 4 YEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARL----RKSQAV 59
Query: 318 LLIADVQPEDFGNYSCVADNSLGR 341
L I +VQ +D G Y C A+NS G+
Sbjct: 60 LEIPNVQLDDAGIYECRAENSRGK 83
>AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein.
Length = 595
Score = 80.6 bits (190), Expect = 1e-14
Identities = 71/218 (32%), Positives = 94/218 (43%), Gaps = 20/218 (9%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+DAG Y C+ + + D +++ V + + + R VT G +A+L CRA G P PT
Sbjct: 21 RDAGTYTCRAVNELG-DASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPT 79
Query: 206 VTWHRLNDS--SSRLGEG-------PQ---LQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
VTW R + RLG G P L + Y C N G V E
Sbjct: 80 VTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFG-KVQAEA 138
Query: 254 QLQVL--YPPEITVERSWVHTGEGFRAELVCTVLADPP-AEVSWYQNSFPLSASERVTMS 310
+L V PP+I V EG L C VLA P E W ++ PL R ++
Sbjct: 139 RLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIR 198
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
A GS H + E G YSCVA N+ G R VE+
Sbjct: 199 ADGSLH---LDRALQEHAGRYSCVATNTAGSQHRDVEL 233
Score = 77.8 bits (183), Expect = 8e-14
Identities = 73/240 (30%), Positives = 99/240 (41%), Gaps = 21/240 (8%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGN 201
R + + AG Y C ++ A Q VE++V R P H G A L C A+G
Sbjct: 207 RALQEHAGRYSC-VATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGV 265
Query: 202 PVPTVTWHR-LNDSSSR-----LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQL 255
P PT+TW + N +SR + + L +++ G Y CT N VG E +L
Sbjct: 266 PAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFS-SQEMRL 324
Query: 256 QVLYPPEITVERS-------WVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL-SASERV 307
V P I + S V G L C PP V+W ++S P+ + R
Sbjct: 325 SVNTKPRIHMNGSRNADVPLQVTAKAGEEVTLDCEAKGSPPPLVTWTKDSRPVPPITNRY 384
Query: 308 TMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPH 367
+ GS L +A VQ D G+Y C A N G A H V G G + P PH
Sbjct: 385 GLLPSGS---LRLAQVQVGDSGHYECTASNPAGSA-SHRYVLGVQGRTSW-QPQSLPVPH 439
Score = 66.5 bits (155), Expect = 2e-10
Identities = 59/219 (26%), Positives = 87/219 (39%), Gaps = 16/219 (7%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLV---PPSVRASPETRHVTARRGGAAVLECRA-AGN 201
+D YVC+ + + Q ++ PP + +S T V G L C AG
Sbjct: 118 EDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPT--VRVLEGQPVSLPCIVLAGR 175
Query: 202 PVPTVTWHRLN-----DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P+P W + S + L L R + H G Y+C N G + +L
Sbjct: 176 PLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQ-HRDVELV 234
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL-SASERVTMSARGSN 315
V PP I + T EG A L C P ++W + + L S +S G
Sbjct: 235 VQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEG-- 292
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
TLLIA +D G Y C A N++G + + + +S P
Sbjct: 293 -TLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKP 330
Score = 51.2 bits (117), Expect = 8e-06
Identities = 42/148 (28%), Positives = 61/148 (41%), Gaps = 7/148 (4%)
Query: 223 QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVC 282
+L++ + G Y C N +G E QL V + P++T V G A L C
Sbjct: 12 KLRIPAAQERDAGTYTCRAVNELGD-ASAEIQLAVGHAPQLTELPRDVTVELGRSALLAC 70
Query: 283 TVLADPPAEVSWYQ-NSFPLS---ASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNS 338
PP V+W + + PL + R + S + + L V PED Y C A N
Sbjct: 71 RATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNV 130
Query: 339 LGR--ARRHVEVSGRPGPARFTSPPLAR 364
G+ A + V+G P +S P R
Sbjct: 131 FGKVQAEARLIVTGHAPPQIASSAPTVR 158
>X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane
heparan sulfate proteoglycan core protein protein.
Length = 4393
Score = 79.0 bits (186), Expect = 4e-14
Identities = 67/232 (28%), Positives = 88/232 (37%), Gaps = 22/232 (9%)
Query: 147 DAGDYVCQISDRV--ARDQVHTVE---VLVPPSVRASPETRHVTARRGGAAVLECRAAGN 201
DAG YVC + + A+ QV + + P + + E +T G A L C A G+
Sbjct: 3181 DAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGS 3240
Query: 202 PVPTVTWHRLNDS---SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
P T+ W +L RL EG L + R+ + G Y C + G T L V
Sbjct: 3241 PARTIHWSKLRSPLPWQHRL-EGDTLIIPRVAQQDSGQYICNATSPAGHAEAT-IILHVE 3298
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ--NSFPLSASERVTMSARGSNH 316
PP T G +L C PP W + +S P A+ R N
Sbjct: 3299 SPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATAR--------NE 3350
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVE--VSGRPGPARFTSPPLARAP 366
L PED G Y C N +G A + V G PG TS P P
Sbjct: 3351 LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTP 3402
Score = 78.6 bits (185), Expect = 5e-14
Identities = 63/223 (28%), Positives = 94/223 (42%), Gaps = 14/223 (6%)
Query: 149 GDYVCQISDRVARDQVHTVEVLVP-PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
G Y+CQ + Q V+ PSV + T T G A EC A G+P P VT
Sbjct: 3464 GTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQVT 3523
Query: 208 WHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITV 265
W ++ + G ++++ +E G Y CT N G + L V P+I++
Sbjct: 3524 WSKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAGT-TQSHVLLLVQALPQISM 3582
Query: 266 ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQP 325
+ V G A C P ++SW + L R+ N+ L++ VQP
Sbjct: 3583 PQE-VRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPDSRL------ENNMLMLPSVQP 3635
Query: 326 EDFGNYSCVADNSLGRAR--RHVEVSGRPGPARFTSPPLARAP 366
+D G Y C A N G+ + H++V R P FT P + P
Sbjct: 3636 QDAGTYVCTATNRQGKVKAFAHLQVPERVVP-YFTQTPYSFLP 3677
Score = 68.9 bits (161), Expect = 4e-11
Identities = 58/219 (26%), Positives = 90/219 (41%), Gaps = 20/219 (9%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHV---------TARRGGAAVLECR 197
D+G+YVC+ + +Q + V VPPS +S R T ++G A +C
Sbjct: 2987 DSGEYVCRAAGGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCL 3046
Query: 198 AAGNPVP-TVTW----HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
P ++ W L D+ G + + + G Y C N G +
Sbjct: 3047 IHDGAAPISLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGV-AQSV 3105
Query: 253 FQLQVLYPPEITVERS---WVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTM 309
L V PP ++V WV G+ E C +P + W + S + E+ T
Sbjct: 3106 VNLSVHGPPTVSVLPEGPVWVKVGKAVTLE--CVSAGEPRSSARWTRISSTPAKLEQRTY 3163
Query: 310 SARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
S+ L I+ +P D G Y C+A N+LG A++ VEV
Sbjct: 3164 GLMDSHTVLQISSAKPSDAGTYVCLAQNALGTAQKQVEV 3202
Score = 67.3 bits (157), Expect = 1e-10
Identities = 68/229 (29%), Positives = 93/229 (40%), Gaps = 31/229 (13%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVL-----------VPPS---VRASPETRHVTARRGGA 191
D+G+YVC++ + + TV VL VP S +R P + HV G
Sbjct: 2113 DSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVA--EGQT 2170
Query: 192 AVLECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP-- 247
L C G VTWH+ S + G L+L ++ G Y C V GP
Sbjct: 2171 LDLNCVVPGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLE 2230
Query: 248 -PVVTEFQLQVLYPP--EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
V+ + V+ P + +E S EG +L C V A+V+WY+ L A
Sbjct: 2231 ASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPAR 2290
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
+V RGS L I P D G Y C A N + A V V+G G
Sbjct: 2291 HQV----RGSR--LYIFQASPADAGQYVCRASNGM-EASITVTVTGTQG 2332
Score = 65.7 bits (153), Expect = 4e-10
Identities = 62/212 (29%), Positives = 86/212 (40%), Gaps = 15/212 (7%)
Query: 147 DAGDYVCQISDRVARDQ-VHTVEVLVPPSVRASPETRH---VTARRGGAAVLECRAAGNP 202
DAG YVC S+ A DQ T+ V ++ A + H +T + G A C A G+P
Sbjct: 1836 DAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSP 1895
Query: 203 VPTVTWHRLNDS---SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTE-FQLQVL 258
PT+ W + G L+L +E Y C + G V +
Sbjct: 1896 TPTLEWTGGPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGG 1955
Query: 259 YPPEITV--ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
P + V ER+ VH G R L C P A ++W + L R S R
Sbjct: 1956 GGPRVQVSPERTQVHAGRTVR--LYCRAAGVPSATITWRKEGGSLPPQAR---SERTDIA 2010
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
TLLI + D G Y CVA + G A+ ++V
Sbjct: 2011 TLLIPAITTADAGFYLCVATSPAGTAQARIQV 2042
Score = 62.9 bits (146), Expect = 3e-09
Identities = 63/217 (29%), Positives = 85/217 (39%), Gaps = 24/217 (11%)
Query: 147 DAGDYVCQI----SDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNP 202
D Y+C+ +VAR +H V P V+ SPE V A G L CRAAG P
Sbjct: 1929 DQAQYLCRAHSSAGQQVARAVLH-VHGGGGPRVQVSPERTQVHA--GRTVRLYCRAAGVP 1985
Query: 203 VPTVTWHRLNDS-----SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
T+TW + S S + L + + G Y C + G Q+ V
Sbjct: 1986 SATITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGT-AQARIQVVV 2044
Query: 258 LYP-----PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
L P + +E S EG +L C V A+V+WY+ L +V
Sbjct: 2045 LSASDASQPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPHHTQV----H 2100
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
GS L + V P D G Y C +N G + VS
Sbjct: 2101 GSR--LRLPQVSPADSGEYVCRVENGSGPKEASITVS 2135
Score = 60.5 bits (140), Expect = 1e-08
Identities = 68/249 (27%), Positives = 96/249 (38%), Gaps = 34/249 (13%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTVEVLVP----PS-------VRASPETRHVTARRGG 190
+M D+G+YVC+ ++ + + V + P PS +R + HV G
Sbjct: 2687 QMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVA--EGE 2744
Query: 191 AAVLECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP- 247
L C G VTWH+ S S G +L+L + G Y C V GP
Sbjct: 2745 TLDLNCVVPGQAHAQVTWHKRGGSLPSYHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPL 2804
Query: 248 ---PVVT-----EFQLQVLYP---PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ 296
+VT + V P P I +E S EG +L C V A+V+W++
Sbjct: 2805 EASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHK 2864
Query: 297 NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRP-GPA 355
L A +V L + V P D G YSC S G V V+ P P
Sbjct: 2865 RGGNLPARHQV------HGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPG 2918
Query: 356 RFTSPPLAR 364
+P LA+
Sbjct: 2919 PIPAPGLAQ 2927
Score = 56.8 bits (131), Expect = 2e-07
Identities = 64/248 (25%), Positives = 92/248 (37%), Gaps = 32/248 (12%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSV----RASP----ETRHVTARRGGAAVLECRA 198
D+G+YVC +S+ + + + R SP E+ T G L C
Sbjct: 2596 DSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPRVSPPIRIESSSPTVVEGQTLDLNCVV 2655
Query: 199 AGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP---PVVTEF 253
A P +TW++ S S G L+L ++ G Y C +N + +V
Sbjct: 2656 ARQPQAIITWYKRGGSLPSRHQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISV 2715
Query: 254 QLQVLYPPE------ITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERV 307
P I +E S H EG +L C V A+V+W++ L + +
Sbjct: 2716 SPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSYHQ- 2774
Query: 308 TMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV----EVSGRPG---PARFTSP 360
RGS L + V P D G Y C S G V E SG PA +P
Sbjct: 2775 ---TRGSR--LRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAP 2829
Query: 361 PLARAPHS 368
P+ P S
Sbjct: 2830 PIRIEPSS 2837
Score = 55.6 bits (128), Expect = 4e-07
Identities = 72/261 (27%), Positives = 103/261 (39%), Gaps = 38/261 (14%)
Query: 147 DAGDYVCQI---SDRVARDQVHTVE------VLVP-----PSVRASPETRHVTARRGGAA 192
D+G+YVC++ S + + T+E V VP P +R P + V G
Sbjct: 2789 DSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVA--EGQTL 2846
Query: 193 VLECRAAGNPVPTVTWHRL--NDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGP--- 247
L+C G VTWH+ N + GP L+L+++ G Y+C V G
Sbjct: 2847 DLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEA 2906
Query: 248 PVVTEFQLQVLYP-------PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFP 300
V+ + P I +E S H EG +L C V A+V+WY+
Sbjct: 2907 SVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGS 2966
Query: 301 LSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG---RARRHVEVSGRPGPA-R 356
L A + GS L + V P D G Y C A G A V V G + R
Sbjct: 2967 LPARHQ----THGSQ--LRLHHVSPADSGEYVCRAAGGPGPEQEASFTVTVPPSEGSSYR 3020
Query: 357 FTSPPLARAPHSYTLSFAVDS 377
SP ++ P S T+ D+
Sbjct: 3021 LRSPVISIDPPSSTVQQGQDA 3041
Score = 54.4 bits (125), Expect = 9e-07
Identities = 58/226 (25%), Positives = 88/226 (38%), Gaps = 28/226 (12%)
Query: 147 DAGDYVCQI---SDRVARDQVHTVEVLVPPSVRA---------SPETRHVTARRGGAAVL 194
D+G+Y CQ+ S + + T+E P + A + HVT G L
Sbjct: 2889 DSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVT--EGQTLDL 2946
Query: 195 ECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
C G VTW++ S + G QL+L + G Y C G GP
Sbjct: 2947 NCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHHVSPADSGEYVCRAAGGPGPEQEAS 3006
Query: 253 FQLQV---------LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA 303
F + V L P I+++ +G A C ++ D A +S +
Sbjct: 3007 FTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKC-LIHDGAAPISLEWKTRNQEL 3065
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+ V +S GS + I +P + G Y CVA N+ G A+ V +S
Sbjct: 3066 EDNVHISPNGS--IITIVGTRPSNHGTYRCVASNAYGVAQSVVNLS 3109
Score = 54.0 bits (124), Expect = 1e-06
Identities = 59/237 (24%), Positives = 93/237 (39%), Gaps = 33/237 (13%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASP------------ETRHVTARRGGAAVL 194
D+G+YVC++ V VLV R S E+ + G L
Sbjct: 2499 DSGEYVCRV---VGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDL 2555
Query: 195 ECRAAGNPVPTVTWHRLNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPP---- 248
C A T+TW++ S S G +L++ ++ G Y C V NG G
Sbjct: 2556 NCLVASQAPHTITWYKRGGSLPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSL 2615
Query: 249 VVT-----EFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA 303
+VT + + PP I +E S EG +L C V P A ++WY+ L +
Sbjct: 2616 IVTIQGSGSSHVPRVSPP-IRIESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPS 2674
Query: 304 SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
+ GS+ L + + D G Y C A+N++ + +S P ++P
Sbjct: 2675 RHQ----THGSH--LRLHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAP 2725
Score = 49.6 bits (113), Expect = 3e-05
Identities = 69/271 (25%), Positives = 93/271 (34%), Gaps = 29/271 (10%)
Query: 102 TIYENSETSVALAILGATGHTNVWETTRRITSEQHGNTNFRM-IFQ----DAGDYVCQIS 156
T+ E ++ + G W +H R+ IFQ DAG YVC+ S
Sbjct: 2257 TVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRAS 2316
Query: 157 DRVARDQVHTVEV-----LVPPSVRASP---ETRHVTARRGGAAVLECRAAGNPVPTVTW 208
+ + TV L P+ P E G L C G VTW
Sbjct: 2317 NGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTW 2376
Query: 209 HRLNDSSS--RLGEGPQLQLSRLERHHGGVYACTVDNGVGP---PVVTEFQLQVLYP--- 260
H+ S G L+L + G Y C V P V+ + P
Sbjct: 2377 HKRGGSLPVRHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALG 2436
Query: 261 --PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
P + +E S EG +L C V A+V+W++ L A +V GS L
Sbjct: 2437 VTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQV----HGSRLRL 2492
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
L V P D G Y C S G V V+
Sbjct: 2493 L--QVTPADSGEYVCRVVGSSGTQEASVLVT 2521
Score = 48.8 bits (111), Expect = 4e-05
Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 2/83 (2%)
Query: 260 PPEI-TVERSWVHTGEGFRAELVCTVLADP-PAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP++ T R + G C + P P ++W N + + RVT+++ G T
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPAPFLINWRLNWGHIPSQPRVTVTSEGGRGT 464
Query: 318 LLIADVQPEDFGNYSCVADNSLG 340
L+I DV+ D G Y+C A N+ G
Sbjct: 465 LIIRDVKESDQGAYTCEAMNARG 487
Score = 41.5 bits (93), Expect = 0.007
Identities = 55/209 (26%), Positives = 76/209 (36%), Gaps = 25/209 (11%)
Query: 163 QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGP 222
+VH +VP S R + RG R G PVP+ T R +G
Sbjct: 1682 EVHPARSIVPQG--GSHSLRCQVSGRGPHYFYWSREDGRPVPSGTQQR--------HQGS 1731
Query: 223 QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE----ITVERSWVHT-GEGFR 277
+L ++ GVY CT N + + +L V P +TVE + G
Sbjct: 1732 ELHFPSVQPSDAGVYICTCRN-LHRSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGAD 1790
Query: 278 AELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADN 337
+CT + PA Y + + ++ A N L I +VQ D G Y C N
Sbjct: 1791 VTFICTAKSKSPA----YTLVWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGSN 1846
Query: 338 SL----GRARRHVEVSGR-PGPARFTSPP 361
G A HV+ SG P PP
Sbjct: 1847 MFAMDQGTATLHVQASGTLSAPVVSIHPP 1875
>U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion protein
protein.
Length = 837
Score = 79.0 bits (186), Expect = 4e-14
Identities = 57/217 (26%), Positives = 94/217 (43%), Gaps = 24/217 (11%)
Query: 143 MIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGN 201
+I D G YVC+ +++ D+ ++V V P + + ++ T G L C A G
Sbjct: 271 IINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHII---QLKNETTYENGQVTLVCDAEGE 327
Query: 202 PVPTVTWHRLNDSSSRLGEGPQLQLSRLE--RHHG--------------GVYACTVDNGV 245
P+P +TW R D + EG + R+E HG G Y C + +
Sbjct: 328 PIPEITWKRAVDGFT-FTEGDKSPDGRIEVKGQHGSSSLHIKDVKLSGSGRYDCEAASRI 386
Query: 246 GPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE 305
G + + L + Y P+ ++ ++ EG + C V ++PPA + W ++ L A
Sbjct: 387 GGHQKSMY-LDIEYAPKFISNQTIYYSWEGNPINISCDVKSNPPASIHWRRDKLVLPAKN 445
Query: 306 RVTMS--ARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
+ + G L IA DFG Y+C A N +G
Sbjct: 446 TTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATNHIG 482
Score = 72.1 bits (169), Expect = 4e-12
Identities = 57/212 (26%), Positives = 94/212 (44%), Gaps = 22/212 (10%)
Query: 147 DAGDYVCQISDRV-ARDQVHTVEVLV----PPSVRASPETRHVTARRGGAAVLECRAAGN 201
D G Y C+ RV AR ++ +++V PP++ ++ + TA RG CRA+G+
Sbjct: 180 DEGIYRCE--GRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGS 237
Query: 202 PVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQL 255
P P ++W R N+ G +L + + GG Y C N G F L
Sbjct: 238 PEPAISWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAF-L 296
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ--NSFPLSASE-----RVT 308
QV P I ++ T E + LVC +P E++W + + F + + R+
Sbjct: 297 QVFVQPHI-IQLKNETTYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSPDGRIE 355
Query: 309 MSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
+ + + +L I DV+ G Y C A + +G
Sbjct: 356 VKGQHGSSSLHIKDVKLSGSGRYDCEAASRIG 387
Score = 66.5 bits (155), Expect = 2e-10
Identities = 54/212 (25%), Positives = 91/212 (42%), Gaps = 12/212 (5%)
Query: 139 TNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRA 198
T + +DAG Y CQ +D + Q TV + + + ++G A + CR
Sbjct: 79 TIYNANIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCRV 138
Query: 199 AGNPVPTVTWHRLND-----SSSRLG--EGPQLQLSRLERHHGGVYACTVD-NGVGPPVV 250
+ +P P V+W N+ S +RL LQ+ + + G+Y C G
Sbjct: 139 SSSPAPAVSWLYHNEEVTTISDNRLAMLANNNLQILNINKSDEGIYRCEGRVEARGEIDF 198
Query: 251 TEFQLQVLYPPEITV-ERSWVHTGE-GFRAELVCTVLADPPAEVSWYQNSFPLSASERVT 308
+ + V PP I++ ++S+ T E G C P +SW++N + +E+
Sbjct: 199 RDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKYI 258
Query: 309 MSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
+ +GSN L + ++ D G Y C A N G
Sbjct: 259 L--KGSNTELTVRNIINSDGGPYVCRATNKAG 288
Score = 37.1 bits (82), Expect = 0.14
Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 262 EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ-NSFPLSASERVTMSARGSNHTLLI 320
++T+ S V G CT + +P + + WY + +++RV + G L I
Sbjct: 22 QVTISLSKVELSVGESKFFTCTAIGEPRS-IDWYNPQGEKIISTQRVVVQKGGVRSRLTI 80
Query: 321 ADVQPEDFGNYSCVADNSLGRAR 343
+ ED G Y C A ++ G+ +
Sbjct: 81 YNANIEDAGIYRCQATDAKGQTQ 103
>BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 78.6 bits (185), Expect = 5e-14
Identities = 61/219 (27%), Positives = 97/219 (44%), Gaps = 20/219 (9%)
Query: 141 FRMIFQDAGDYVCQISDRVARDQVHTVEVLVP--PSVRASPETRHVTARRGGAAVLECRA 198
F + F D G Y C +++ + ++ V PS +P +T R G A LEC A
Sbjct: 568 FNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTP--MDLTIRTGAMARLECAA 625
Query: 199 AGNPVPTVTWHRLNDSS------SRLGEGPQ---LQLSRLERHHGGVYACTVDNGVGPPV 249
G+P P ++W + + R+ P+ ++ ++ G+Y+C N G +
Sbjct: 626 EGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNTAGG-L 684
Query: 250 VTEFQLQVLYPPEIT--VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERV 307
L VL P +E V GE A L C P ++W ++ PL +ER
Sbjct: 685 SANASLTVLETPSFIRPLEDKTVTRGE--TAVLQCIAGGSPAPRLNWTKDDGPLLVTERH 742
Query: 308 TMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
+A +N L+I D ED G Y+C+ N+LG R H+
Sbjct: 743 FFAA--ANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHI 779
>BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 78.6 bits (185), Expect = 5e-14
Identities = 61/219 (27%), Positives = 97/219 (44%), Gaps = 20/219 (9%)
Query: 141 FRMIFQDAGDYVCQISDRVARDQVHTVEVLVP--PSVRASPETRHVTARRGGAAVLECRA 198
F + F D G Y C +++ + ++ V PS +P +T R G A LEC A
Sbjct: 568 FNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTP--MDLTIRTGAMARLECAA 625
Query: 199 AGNPVPTVTWHRLNDSS------SRLGEGPQ---LQLSRLERHHGGVYACTVDNGVGPPV 249
G+P P ++W + + R+ P+ ++ ++ G+Y+C N G +
Sbjct: 626 EGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNTAGG-L 684
Query: 250 VTEFQLQVLYPPEIT--VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERV 307
L VL P +E V GE A L C P ++W ++ PL +ER
Sbjct: 685 SANASLTVLETPSFIRPLEDKTVTRGE--TAVLQCIAGGSPAPRLNWTKDDGPLLVTERH 742
Query: 308 TMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
+A +N L+I D ED G Y+C+ N+LG R H+
Sbjct: 743 FFAA--ANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHI 779
>BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion
molecule 2 protein.
Length = 837
Score = 78.6 bits (185), Expect = 5e-14
Identities = 57/217 (26%), Positives = 94/217 (43%), Gaps = 24/217 (11%)
Query: 143 MIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGN 201
+I D G YVC+ +++ D+ ++V V P + + ++ T G L C A G
Sbjct: 271 IINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHII---QLKNETTYENGQVTLVCDAEGE 327
Query: 202 PVPTVTWHRLNDSSSRLGEGPQLQLSRLE--RHHG--------------GVYACTVDNGV 245
P+P +TW R D + EG + R+E HG G Y C + +
Sbjct: 328 PIPEITWKRAVDGFT-FTEGDKSLDGRIEVKGQHGSSSLHIKDVKLSDSGRYDCEAASRI 386
Query: 246 GPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE 305
G + + L + Y P+ ++ ++ EG + C V ++PPA + W ++ L A
Sbjct: 387 GGHQKSMY-LDIEYAPKFISNQTIYYSWEGNPINISCDVKSNPPASIHWRRDKLVLPAKN 445
Query: 306 RVTMS--ARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
+ + G L IA DFG Y+C A N +G
Sbjct: 446 TTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATNHIG 482
Score = 74.9 bits (176), Expect = 6e-13
Identities = 58/212 (27%), Positives = 95/212 (44%), Gaps = 22/212 (10%)
Query: 147 DAGDYVCQISDRV-ARDQVHTVEVLV----PPSVRASPETRHVTARRGGAAVLECRAAGN 201
D G Y C+ RV AR ++ +++V PP++ ++ + TA RG CRA+G+
Sbjct: 180 DEGIYRCE--GRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGS 237
Query: 202 PVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQL 255
P P ++W R N+ G +L + + GG Y C N G F L
Sbjct: 238 PEPAISWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAF-L 296
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ--NSFPLSASE-----RVT 308
QV P I ++ T E + LVC +P E++W + + F + + R+
Sbjct: 297 QVFVQPHI-IQLKNETTYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSLDGRIE 355
Query: 309 MSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
+ + + +L I DV+ D G Y C A + +G
Sbjct: 356 VKGQHGSSSLHIKDVKLSDSGRYDCEAASRIG 387
Score = 66.5 bits (155), Expect = 2e-10
Identities = 55/228 (24%), Positives = 100/228 (43%), Gaps = 16/228 (7%)
Query: 127 TTRRITSEQHGNTNFRMIF----QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETR 182
+T+R+ ++ G + I+ +DAG Y CQ +D + Q TV + + +
Sbjct: 63 STQRVVVQKEGVRSRLTIYNANIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVS 122
Query: 183 HVTARRGGAAVLECRAAGNPVPTVTW--HR-----LNDSSSRLGEGPQLQLSRLERHHGG 235
++G A + CR + +P P V+W H ++D+ + LQ+ + + G
Sbjct: 123 PQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRFAMLANNNLQILNINKSDEG 182
Query: 236 VYACTVD-NGVGPPVVTEFQLQVLYPPEITV-ERSWVHTGE-GFRAELVCTVLADPPAEV 292
+Y C G + + V PP I++ ++S+ T E G C P +
Sbjct: 183 IYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAI 242
Query: 293 SWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
SW++N + +E+ + +GSN L + ++ D G Y C A N G
Sbjct: 243 SWFRNGKLIEENEKYIL--KGSNTELTVRNIINSDGGPYVCRATNKAG 288
Score = 38.3 bits (85), Expect = 0.062
Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 262 EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ-NSFPLSASERVTMSARGSNHTLLI 320
++T+ S V G CT + +P + + WY + +++RV + G L I
Sbjct: 22 QVTISLSKVELSVGESKFFTCTAIGEPES-IDWYNPQGEKIISTQRVVVQKEGVRSRLTI 80
Query: 321 ADVQPEDFGNYSCVADNSLGRAR 343
+ ED G Y C A ++ G+ +
Sbjct: 81 YNANIEDAGIYRCQATDAKGQTQ 103
>AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 78.6 bits (185), Expect = 5e-14
Identities = 61/219 (27%), Positives = 97/219 (44%), Gaps = 20/219 (9%)
Query: 141 FRMIFQDAGDYVCQISDRVARDQVHTVEVLVP--PSVRASPETRHVTARRGGAAVLECRA 198
F + F D G Y C +++ + ++ V PS +P +T R G A LEC A
Sbjct: 568 FNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTP--MDLTIRTGAMARLECAA 625
Query: 199 AGNPVPTVTWHRLNDSS------SRLGEGPQ---LQLSRLERHHGGVYACTVDNGVGPPV 249
G+P P ++W + + R+ P+ ++ ++ G+Y+C N G +
Sbjct: 626 EGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNTAGG-L 684
Query: 250 VTEFQLQVLYPPEIT--VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERV 307
L VL P +E V GE A L C P ++W ++ PL +ER
Sbjct: 685 SANASLTVLETPSFIRPLEDKTVTRGE--TAVLQCIAGGSPAPRLNWTKDDGPLLVTERH 742
Query: 308 TMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
+A +N L+I D ED G Y+C+ N+LG R H+
Sbjct: 743 FFAA--ANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHI 779
>AF478693-1|AAM77220.1| 955|Homo sapiens
glycosyl-phosphatidyl-inositol-MAM protein.
Length = 955
Score = 78.6 bits (185), Expect = 5e-14
Identities = 79/277 (28%), Positives = 109/277 (39%), Gaps = 30/277 (10%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEV-----LVPPSVRASPETRHVTARRGGAAVLECRAA 199
F D G Y+C S A +VEV VPP++ VT R G A L+C
Sbjct: 407 FSDYGTYLCMASFPGAPVPDLSVEVNISSETVPPTISVPKGRAVVTVREGSPAELQCEVR 466
Query: 200 GNPVPTVTWHRLNDSSSRLGEG--------PQLQLSRLERHHGGVYACTVD--NGVG-PP 248
G P P V W R++ ++ L G +L+L R+ R G Y C NG P
Sbjct: 467 GKPRPPVLWSRVDKEAALLPSGLPLEETPDGKLRLERVSRDMSGTYRCQTARYNGFNVRP 526
Query: 249 VVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS---WYQNSFPLSASE 305
+ QL V +PPE+ V G L C++L P ++ W L
Sbjct: 527 REAQVQLNVQFPPEVEPSSQDVRQALGRPVLLRCSLLRGSPQRIASAVWRFKGQLLPPPP 586
Query: 306 RVTMSARGSNHTLLIAD-VQPEDFGNYSCVADNSLGRARRHVEVSGRP-GPARFTSPPLA 363
V +A +H L D V + G+Y C N +G A +VS + P + P
Sbjct: 587 VVPAAAEAPDHAELRLDAVTRDSSGSYECSVSNDVGSAACLFQVSAKAYSPEFYFDTPNP 646
Query: 364 RAPH------SYTLSFA---VDSYPPLDELRLLYRQL 391
H SY L + D+ P+ RL RQL
Sbjct: 647 TRSHKLSKNYSYVLQWTQREPDAVDPVLNYRLSIRQL 683
Score = 77.0 bits (181), Expect = 1e-13
Identities = 51/169 (30%), Positives = 81/169 (47%), Gaps = 17/169 (10%)
Query: 182 RHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSS-RLGE----GPQLQLSRLERHHGGV 236
R T R G +L+C G+P P V W + S+S + E L++ R+ R GG
Sbjct: 46 RVYTIREGDTLMLQCLVTGHPRPQVRWTKTAGSASDKFQETSVFNETLRIERIARTQGGR 105
Query: 237 YACTVDNGVGPPVVTEFQLQVLY--PPEITVERSWVHTGEGFRAE----LVCTVLADPPA 290
Y C +NGVG P + ++ V Y P +TV ++ F E L CTV ++PPA
Sbjct: 106 YYCKAENGVGVPAIKSIRVDVQYLDEPMLTVHQTVSDVRGNFYQEKTVFLRCTVNSNPPA 165
Query: 291 EVSWYQNSFPLSASE------RVTMSARGSNHTLLIADVQPEDFGNYSC 333
W + S LS S+ + +G L + +++P+D+ +Y+C
Sbjct: 166 RFIWKRGSDTLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTC 214
Score = 53.2 bits (122), Expect = 2e-06
Identities = 54/214 (25%), Positives = 87/214 (40%), Gaps = 27/214 (12%)
Query: 146 QDAGDYVCQISDRVA---RDQVHTVEVL---VPPSVRASPETRHVTARRGGAAVLECR-A 198
QD Y CQ+S R D+ T + PP+++ S V G ++C
Sbjct: 207 QDYASYTCQVSVRNVCGIPDKAITFRLTNTTAPPALKLSVNETLVV-NPGENVTVQCLLT 265
Query: 199 AGNPVPTVTW-HRLNDSS-SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
G+P+P + W H L +G L + ++ G Y CT N VG P L
Sbjct: 266 GGDPLPQLQWSHGPGPLPLGALAQGGTLSIPSVQARDSGYYNCTATNNVGNPAKKTVNLL 325
Query: 257 V--------LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS--WYQNSFPLSASER 306
V P++ E + G+ + L C V A P +V+ W++N P S+R
Sbjct: 326 VRSMKNATFQITPDVIKESENIQLGQDLK--LSCHVDAVPQEKVTYQWFKNGKPARMSKR 383
Query: 307 VTMSAR-----GSNHTLLIADVQPEDFGNYSCVA 335
+ ++ +L + D+ D+G Y C+A
Sbjct: 384 LLVTRNDPELPAVTSSLELIDLHFSDYGTYLCMA 417
Score = 38.3 bits (85), Expect = 0.062
Identities = 38/129 (29%), Positives = 51/129 (39%), Gaps = 14/129 (10%)
Query: 219 GEGPQLQLSRLERHHGGVYACTVD--NGVG-PPVVTEFQL-QVLYPPEITV---ERSWVH 271
GE L+L L Y C V N G P F+L PP + + E V+
Sbjct: 194 GETKVLKLKNLRPQDYASYTCQVSVRNVCGIPDKAITFRLTNTTAPPALKLSVNETLVVN 253
Query: 272 TGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNY 331
GE + + T DP ++ W PL + A TL I VQ D G Y
Sbjct: 254 PGENVTVQCLLTG-GDPLPQLQWSHGPGPLP------LGALAQGGTLSIPSVQARDSGYY 306
Query: 332 SCVADNSLG 340
+C A N++G
Sbjct: 307 NCTATNNVG 315
>AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein.
Length = 1073
Score = 78.6 bits (185), Expect = 5e-14
Identities = 61/219 (27%), Positives = 97/219 (44%), Gaps = 20/219 (9%)
Query: 141 FRMIFQDAGDYVCQISDRVARDQVHTVEVLVP--PSVRASPETRHVTARRGGAAVLECRA 198
F + F D G Y C +++ + ++ V PS +P +T R G A LEC A
Sbjct: 576 FNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTP--MDLTIRTGAMARLECAA 633
Query: 199 AGNPVPTVTWHRLNDSS------SRLGEGPQ---LQLSRLERHHGGVYACTVDNGVGPPV 249
G+P P ++W + + R+ P+ ++ ++ G+Y+C N G +
Sbjct: 634 EGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNTAGG-L 692
Query: 250 VTEFQLQVLYPPEIT--VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERV 307
L VL P +E V GE A L C P ++W ++ PL +ER
Sbjct: 693 SANASLTVLETPSFIRPLEDKTVTRGE--TAVLQCIAGGSPAPRLNWTKDDGPLLVTERH 750
Query: 308 TMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
+A +N L+I D ED G Y+C+ N+LG R H+
Sbjct: 751 FFAA--ANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHI 787
>BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 78.2 bits (184), Expect = 6e-14
Identities = 63/221 (28%), Positives = 92/221 (41%), Gaps = 16/221 (7%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEVLVP--PSVRASPETRHVTARRGGAAVLECRAAGNP 202
F G Y C IS+ ++ V PS +P +T R G A LEC A G+P
Sbjct: 573 FASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTP--MDLTIRAGAMARLECAAVGHP 630
Query: 203 VPTVTWHRLNDSS------SRLGEGPQ---LQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
P + W + + R+ P+ + ++ GVY+CT N G +
Sbjct: 631 APQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGS-ISANA 689
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
L VL P +G A L C PP +++W ++ PL +ER +A
Sbjct: 690 TLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAA-- 747
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
N L+I D D G Y+C N+LG R +V +S P P
Sbjct: 748 GNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTP 788
Score = 55.2 bits (127), Expect = 5e-07
Identities = 42/144 (29%), Positives = 61/144 (42%), Gaps = 6/144 (4%)
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCT 283
L+L +E G Y C + N G + +L V P T + G A L C
Sbjct: 566 LRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECA 625
Query: 284 VLADPPAEVSWYQN---SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
+ P +++W ++ FP +A ER M + I DV+ ED G YSC A NS G
Sbjct: 626 AVGHPAPQIAWQKDGGTDFP-AARER-RMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAG 683
Query: 341 RARRHVEVSGRPGPARFTSPPLAR 364
+ ++ P+ F P L R
Sbjct: 684 SISANATLTVLETPS-FLRPLLDR 706
>BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 78.2 bits (184), Expect = 6e-14
Identities = 63/221 (28%), Positives = 92/221 (41%), Gaps = 16/221 (7%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEVLVP--PSVRASPETRHVTARRGGAAVLECRAAGNP 202
F G Y C IS+ ++ V PS +P +T R G A LEC A G+P
Sbjct: 573 FASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTP--MDLTIRAGAMARLECAAVGHP 630
Query: 203 VPTVTWHRLNDSS------SRLGEGPQ---LQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
P + W + + R+ P+ + ++ GVY+CT N G +
Sbjct: 631 APQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGS-ISANA 689
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
L VL P +G A L C PP +++W ++ PL +ER +A
Sbjct: 690 TLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAA-- 747
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
N L+I D D G Y+C N+LG R +V +S P P
Sbjct: 748 GNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTP 788
Score = 55.2 bits (127), Expect = 5e-07
Identities = 42/144 (29%), Positives = 61/144 (42%), Gaps = 6/144 (4%)
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCT 283
L+L +E G Y C + N G + +L V P T + G A L C
Sbjct: 566 LRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECA 625
Query: 284 VLADPPAEVSWYQN---SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
+ P +++W ++ FP +A ER M + I DV+ ED G YSC A NS G
Sbjct: 626 AVGHPAPQIAWQKDGGTDFP-AARER-RMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAG 683
Query: 341 RARRHVEVSGRPGPARFTSPPLAR 364
+ ++ P+ F P L R
Sbjct: 684 SISANATLTVLETPS-FLRPLLDR 706
>AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein.
Length = 1150
Score = 78.2 bits (184), Expect = 6e-14
Identities = 56/175 (32%), Positives = 79/175 (45%), Gaps = 14/175 (8%)
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSS-----SR-LGEGPQLQL 226
P++ A P+ ++T VLEC A GNP P ++W RL+ S +R LG G L +
Sbjct: 235 PTIIAGPQ--NITTSLHQTVVLECMATGNPKPIISWSRLDHKSIDVFNTRVLGNG-NLMI 291
Query: 227 SRLERHHGGVYACTVDN-GVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVL 285
S + H GVY C G V L VL PP + A VC
Sbjct: 292 SDVRLQHAGVYVCRATTPGTRNFTVAMATLTVLAPPSFVEWPESLTRPRAGTARFVCQAE 351
Query: 286 ADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
P ++SW +N + ++ R+ M N L+I + PED Y C+A+NS G
Sbjct: 352 GIPSPKMSWLKNGRKIHSNGRIKM----YNSKLVINQIIPEDDAIYQCMAENSQG 402
Score = 61.3 bits (142), Expect = 8e-09
Identities = 59/209 (28%), Positives = 85/209 (40%), Gaps = 21/209 (10%)
Query: 180 ETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSR------LGEGPQLQLSRLERHH 233
E + VT R VL+C+A G VTW + S L G L +S +E
Sbjct: 44 EPQDVTVTRKDPVVLDCQAHGEVPIKVTWLKNGAKMSENKRIEVLSNG-SLYISEVEGRR 102
Query: 234 G-----GVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADP 288
G G Y C N G + + L + V+ EG A C + + P
Sbjct: 103 GEQSDEGFYQCLAMNKYGAILSQKAHLALSTISAFEVQPISTEVHEGGVARFACKISSHP 162
Query: 289 PAEVSWYQNSFPLSAS-ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE 347
PA ++W N L + +R+T G L I DV D GNY C+A ++ R+ +E
Sbjct: 163 PAVITWEFNRTTLPMTMDRITALPTG---VLQIYDVSQRDSGNYRCIA-ATVAHRRKSME 218
Query: 348 VSGRPGPAR----FTSPPLARAPHSYTLS 372
S PA+ F +P + P + T S
Sbjct: 219 ASLTVIPAKESKSFHTPTIIAGPQNITTS 247
>AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 78.2 bits (184), Expect = 6e-14
Identities = 63/221 (28%), Positives = 92/221 (41%), Gaps = 16/221 (7%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEVLVP--PSVRASPETRHVTARRGGAAVLECRAAGNP 202
F G Y C IS+ ++ V PS +P +T R G A LEC A G+P
Sbjct: 573 FASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTP--MDLTIRAGAMARLECAAVGHP 630
Query: 203 VPTVTWHRLNDSS------SRLGEGPQ---LQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
P + W + + R+ P+ + ++ GVY+CT N G +
Sbjct: 631 APQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGS-ISANA 689
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
L VL P +G A L C PP +++W ++ PL +ER +A
Sbjct: 690 TLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAA-- 747
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
N L+I D D G Y+C N+LG R +V +S P P
Sbjct: 748 GNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTP 788
Score = 55.2 bits (127), Expect = 5e-07
Identities = 42/144 (29%), Positives = 61/144 (42%), Gaps = 6/144 (4%)
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCT 283
L+L +E G Y C + N G + +L V P T + G A L C
Sbjct: 566 LRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECA 625
Query: 284 VLADPPAEVSWYQN---SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
+ P +++W ++ FP +A ER M + I DV+ ED G YSC A NS G
Sbjct: 626 AVGHPAPQIAWQKDGGTDFP-AARER-RMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAG 683
Query: 341 RARRHVEVSGRPGPARFTSPPLAR 364
+ ++ P+ F P L R
Sbjct: 684 SISANATLTVLETPS-FLRPLLDR 706
>AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein.
Length = 1059
Score = 78.2 bits (184), Expect = 6e-14
Identities = 63/221 (28%), Positives = 92/221 (41%), Gaps = 16/221 (7%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEVLVP--PSVRASPETRHVTARRGGAAVLECRAAGNP 202
F G Y C IS+ ++ V PS +P +T R G A LEC A G+P
Sbjct: 513 FASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTP--MDLTIRAGAMARLECAAVGHP 570
Query: 203 VPTVTWHRLNDSS------SRLGEGPQ---LQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
P + W + + R+ P+ + ++ GVY+CT N G +
Sbjct: 571 APQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGS-ISANA 629
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
L VL P +G A L C PP +++W ++ PL +ER +A
Sbjct: 630 TLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAA-- 687
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
N L+I D D G Y+C N+LG R +V +S P P
Sbjct: 688 GNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTP 728
Score = 55.2 bits (127), Expect = 5e-07
Identities = 42/144 (29%), Positives = 61/144 (42%), Gaps = 6/144 (4%)
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCT 283
L+L +E G Y C + N G + +L V P T + G A L C
Sbjct: 506 LRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECA 565
Query: 284 VLADPPAEVSWYQN---SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
+ P +++W ++ FP +A ER M + I DV+ ED G YSC A NS G
Sbjct: 566 AVGHPAPQIAWQKDGGTDFP-AARER-RMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAG 623
Query: 341 RARRHVEVSGRPGPARFTSPPLAR 364
+ ++ P+ F P L R
Sbjct: 624 SISANATLTVLETPS-FLRPLLDR 646
>AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein.
Length = 1119
Score = 78.2 bits (184), Expect = 6e-14
Identities = 63/221 (28%), Positives = 92/221 (41%), Gaps = 16/221 (7%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEVLVP--PSVRASPETRHVTARRGGAAVLECRAAGNP 202
F G Y C IS+ ++ V PS +P +T R G A LEC A G+P
Sbjct: 573 FASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTP--MDLTIRAGAMARLECAAVGHP 630
Query: 203 VPTVTWHRLNDSS------SRLGEGPQ---LQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
P + W + + R+ P+ + ++ GVY+CT N G +
Sbjct: 631 APQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGS-ISANA 689
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
L VL P +G A L C PP +++W ++ PL +ER +A
Sbjct: 690 TLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAA-- 747
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
N L+I D D G Y+C N+LG R +V +S P P
Sbjct: 748 GNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTP 788
Score = 55.2 bits (127), Expect = 5e-07
Identities = 42/144 (29%), Positives = 61/144 (42%), Gaps = 6/144 (4%)
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCT 283
L+L +E G Y C + N G + +L V P T + G A L C
Sbjct: 566 LRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECA 625
Query: 284 VLADPPAEVSWYQN---SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
+ P +++W ++ FP +A ER M + I DV+ ED G YSC A NS G
Sbjct: 626 AVGHPAPQIAWQKDGGTDFP-AARER-RMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAG 683
Query: 341 RARRHVEVSGRPGPARFTSPPLAR 364
+ ++ P+ F P L R
Sbjct: 684 SISANATLTVLETPS-FLRPLLDR 706
>AK074921-1|BAC11295.1| 697|Homo sapiens protein ( Homo sapiens
cDNA FLJ90440 fis, clone NT2RP3000921, weakly similar to
TUMOR SUPPRESSOR PROTEIN DCC PRECURSOR. ).
Length = 697
Score = 78.2 bits (184), Expect = 6e-14
Identities = 63/221 (28%), Positives = 92/221 (41%), Gaps = 16/221 (7%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEVLVP--PSVRASPETRHVTARRGGAAVLECRAAGNP 202
F G Y C IS+ ++ V PS +P +T R G A LEC A G+P
Sbjct: 151 FASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTP--MDLTIRAGAMARLECAAVGHP 208
Query: 203 VPTVTWHRLNDSS------SRLGEGPQ---LQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
P + W + + R+ P+ + ++ GVY+CT N G +
Sbjct: 209 APQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGS-ISANA 267
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
L VL P +G A L C PP +++W ++ PL +ER +A
Sbjct: 268 TLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAA-- 325
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
N L+I D D G Y+C N+LG R +V +S P P
Sbjct: 326 GNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTP 366
Score = 55.2 bits (127), Expect = 5e-07
Identities = 42/144 (29%), Positives = 61/144 (42%), Gaps = 6/144 (4%)
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCT 283
L+L +E G Y C + N G + +L V P T + G A L C
Sbjct: 144 LRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECA 203
Query: 284 VLADPPAEVSWYQN---SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
+ P +++W ++ FP +A ER M + I DV+ ED G YSC A NS G
Sbjct: 204 AVGHPAPQIAWQKDGGTDFP-AARER-RMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAG 261
Query: 341 RARRHVEVSGRPGPARFTSPPLAR 364
+ ++ P+ F P L R
Sbjct: 262 SISANATLTVLETPS-FLRPLLDR 284
>AY369208-1|AAQ73312.1| 956|Homo sapiens MAM domain-containing
glycosylphosphatidylinositol anchor 2 protein.
Length = 956
Score = 77.8 bits (183), Expect = 8e-14
Identities = 50/171 (29%), Positives = 80/171 (46%), Gaps = 17/171 (9%)
Query: 182 RHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSS-RLGEGP----QLQLSRLERHHGGV 236
R T R G L C G+P P + W + S+S R + L+++ ++RH GG
Sbjct: 48 RVYTIREGETLELTCLVTGHPRPQIRWTKTAGSASDRFQDSSVFNETLRITNIQRHQGGR 107
Query: 237 YACTVDNGVGPPVVTEFQLQVLY--PPEITVERSWVHTGEGFRAE----LVCTVLADPPA 290
Y C +NG+G P + ++ V Y P +TV +S E F E L C ++PP
Sbjct: 108 YYCKAENGLGSPAIKSIRVDVYYLDDPVVTVHQSIGEAKEQFYYERTVFLRCVANSNPPV 167
Query: 291 EVSWYQ-NSFPLSASER-----VTMSARGSNHTLLIADVQPEDFGNYSCVA 335
SW + L S++ +G L + +++P+D+ NYSC+A
Sbjct: 168 RYSWRRGQEVLLQGSDKGVEIYEPFFTQGETKILKLKNLRPQDYANYSCIA 218
Score = 66.5 bits (155), Expect = 2e-10
Identities = 80/334 (23%), Positives = 132/334 (39%), Gaps = 32/334 (9%)
Query: 137 GNTNFRMI---FQDAGDYVCQISDRVARDQVHTVEV-----LVPPSVRASPETRHVTARR 188
G TN +I F D G Y C S + +++V VPP++ E + R
Sbjct: 398 GTTNLDIIDLKFTDFGTYTCVASLKGGGISDISIDVNISSSTVPPNLTVPQEKSPLVTRE 457
Query: 189 GGAAVLECRAAGNPVPTVTWHR------LNDSSSRL-GEGPQLQLSRLERHHGGVYACTV 241
G L+C+ G P P + W R + D S ++ L++ + R G+Y C
Sbjct: 458 GDTIELQCQVTGKPKPIILWSRADKEVAMPDGSMQMESYDGTLRIVNVSREMSGMYRCQT 517
Query: 242 D--NGVG-PPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS 298
NG P QL V YPP + + G+ + C VL P V Y+
Sbjct: 518 SQYNGFNVKPREALVQLIVQYPPAVEPAFLEIRQGQDRSVTMSCRVLRAYPIRVLTYE-- 575
Query: 299 FPLSASERVTMSARGSNHT-LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF 357
+ L T +T + + E++G Y+C N G R V+G+ F
Sbjct: 576 WRLGNKLLRTGQFDSQEYTEYAVKSLSNENYGVYNCSIINEAGAGRCSFLVTGKAYAPEF 635
Query: 358 ---TSPPLARAPH---SYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAAP 411
T P+ + H SY+L + + +D R++ +L I ++ QQ ++ +
Sbjct: 636 YYDTYNPVWQNRHRVYSYSLQWTQMNPDAVD--RIVAYRLGIRQAGQQRWWEQEIKINGN 693
Query: 412 AAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYG 445
KG L +++ L L YE + ++G
Sbjct: 694 IQKGEL---ITYNLTELIKPEAYEVRLTPLTKFG 724
Score = 59.3 bits (137), Expect = 3e-08
Identities = 57/228 (25%), Positives = 91/228 (39%), Gaps = 22/228 (9%)
Query: 152 VCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLEC-RAAGNPVPTVTWHR 210
VC I D++ ++ PS++ + + G A L C G P P++TW R
Sbjct: 223 VCNIPDKMVSFRLSNKTA--SPSIKLLVDDP-IVVNPGEAITLVCVTTGGEPAPSLTWVR 279
Query: 211 LNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVV--TEFQLQVLYPPEITVE 266
+ + G L + + G Y+C +N VG P T ++ L +
Sbjct: 280 SFGTLPEKTVLNGGTLTIPAITSDDAGTYSCIANNNVGNPAKKSTNIIVRALKKGRFWIT 339
Query: 267 RSWVHTGE----GFRAELVCTVLADPPAEV--SWYQNSFPLSASERVTMS-----ARGSN 315
H + G ++ C V A P E+ SW++N PL +SER+ ++
Sbjct: 340 PDPYHKDDNIQIGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGT 399
Query: 316 HTLLIADVQPEDFGNYSCVAD---NSLGRARRHVEVSGRPGPARFTSP 360
L I D++ DFG Y+CVA + V +S P T P
Sbjct: 400 TNLDIIDLKFTDFGTYTCVASLKGGGISDISIDVNISSSTVPPNLTVP 447
Score = 41.1 bits (92), Expect = 0.009
Identities = 25/67 (37%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
EG EL C V P ++ W + + SAS+R S+ N TL I ++Q G Y C
Sbjct: 54 EGETLELTCLVTGHPRPQIRWTKTAG--SASDRFQDSSV-FNETLRITNIQRHQGGRYYC 110
Query: 334 VADNSLG 340
A+N LG
Sbjct: 111 KAENGLG 117
>X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor
protein.
Length = 1040
Score = 77.0 bits (181), Expect = 1e-13
Identities = 60/204 (29%), Positives = 88/204 (43%), Gaps = 10/204 (4%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
F+D G Y C+ + RD V ++V A G C AAG P P
Sbjct: 298 FEDEGTYECEAENSKGRDTVQG-RIIVQAQPEWLKVISDTEADIGSNLRWGCAAAGKPRP 356
Query: 205 TVTWHRLND---SSSRLGE-GPQLQLSRLERHHGGVYACTVDNGVGPPVVT-EFQLQVLY 259
TV W R + S +R+ L+ S+L G+Y C +N G + E +Q L
Sbjct: 357 TVRWLRNGEPLASQNRVEVLAGDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALA 416
Query: 260 PP-EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
P + R + G + C A P A V W + + L S RVT++ G TL
Sbjct: 417 PDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDG---TL 473
Query: 319 LIADVQPEDFGNYSCVADNSLGRA 342
+I ++ D G Y+C A+N +G+A
Sbjct: 474 IIRNISRSDEGKYTCFAENFMGKA 497
Score = 68.1 bits (159), Expect = 7e-11
Identities = 56/197 (28%), Positives = 79/197 (40%), Gaps = 8/197 (4%)
Query: 170 LVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSR--LGEGPQLQLS 227
L PS++A A G LEC A GNPVP + W +++ S S P LQ+
Sbjct: 236 LFAPSIKARFPAE-TYALVGQQVTLECFAFGNPVPRIKWRKVDGSLSPQWTTAEPTLQIP 294
Query: 228 RLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLAD 287
+ G Y C +N G V + ++ V PE S G C
Sbjct: 295 SVSFEDEGTYECEAENSKGRDTV-QGRIIVQAQPEWLKVISDTEADIGSNLRWGCAAAGK 353
Query: 288 PPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE 347
P V W +N PL++ RV + A L + + ED G Y CVA+N G E
Sbjct: 354 PRPTVRWLRNGEPLASQNRVEVLA----GDLRFSKLSLEDSGMYQCVAENKHGTIYASAE 409
Query: 348 VSGRPGPARFTSPPLAR 364
++ + F P+ R
Sbjct: 410 LAVQALAPDFRLNPVRR 426
Score = 59.7 bits (138), Expect = 2e-08
Identities = 81/333 (24%), Positives = 131/333 (39%), Gaps = 32/333 (9%)
Query: 137 GNTNF-RMIFQDAGDYVCQISDR---VARDQVHTVEVLVPPSVRASPETRHVTARRGGAA 192
G+ F ++ +D+G Y C ++ + V+ L P R +P R + A RGG
Sbjct: 378 GDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAP-DFRLNPVRRLIPAARGGEI 436
Query: 193 VLECRAAGNPVPTVTWHRLND---SSSRLGEGPQ--LQLSRLERHHGGVYACTVDNGVGP 247
++ C+ P V W + + +SSR+ P L + + R G Y C +N +G
Sbjct: 437 LIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGK 496
Query: 248 PVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS--WYQNSFPLSASE 305
T L V +IT+ S G L C DP +++ W + FP+ +
Sbjct: 497 ANSTGI-LSVRDATKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDK 555
Query: 306 -----RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH--VEVSGRPG-PARF 357
R T + + + L I + Q G Y+C+A + A + V V G PG P
Sbjct: 556 PGGHYRRT-NVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGPPGPPGGV 614
Query: 358 TSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAAPAAKGSL 417
+ + S D++ P+ + L R G+W V +G+
Sbjct: 615 VVRDIGDTTIQLSWSRGFDNHSPIAKYTLQART-------PPAGKWKQVRTNPANIEGNA 667
Query: 418 THRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ ++ GL P YE V A N G E S
Sbjct: 668 E---TAQVLGLTPWMDYEFRVIASNILGTGEPS 697
Score = 55.6 bits (128), Expect = 4e-07
Identities = 50/166 (30%), Positives = 70/166 (42%), Gaps = 15/166 (9%)
Query: 193 VLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQL--------SRLERHHGGVYACTVDNG 244
+L CRA +P T W ++N + +L G + QL + + GVY C N
Sbjct: 58 LLACRARASPPATYRW-KMNGTEMKLEPGSRHQLVGGNLVIMNPTKAQDAGVYQCLASNP 116
Query: 245 VGPPVVTEFQLQVLYPPEITVE-RSWVHTGEGFRAELVCTVLADPPA-EVSWYQNSFP-- 300
VG V E L+ + E + E R V EG+ L C A P W N FP
Sbjct: 117 VGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRWLLNEFPNF 176
Query: 301 LSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
+ R +S N L IA D GNYSC+A + + + + V
Sbjct: 177 IPTDGRHFVSQTTGN--LYIARTNASDLGNYSCLATSHMDFSTKSV 220
>X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal
glycoprotein protein.
Length = 1040
Score = 77.0 bits (181), Expect = 1e-13
Identities = 60/204 (29%), Positives = 88/204 (43%), Gaps = 10/204 (4%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
F+D G Y C+ + RD V ++V A G C AAG P P
Sbjct: 298 FEDEGTYECEAENSKGRDTVQG-RIIVQAQPEWLKVISDTEADIGSNLRWGCAAAGKPRP 356
Query: 205 TVTWHRLND---SSSRLGE-GPQLQLSRLERHHGGVYACTVDNGVGPPVVT-EFQLQVLY 259
TV W R + S +R+ L+ S+L G+Y C +N G + E +Q L
Sbjct: 357 TVRWLRNGEPLASQNRVEVLAGDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALA 416
Query: 260 PP-EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
P + R + G + C A P A V W + + L S RVT++ G TL
Sbjct: 417 PDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDG---TL 473
Query: 319 LIADVQPEDFGNYSCVADNSLGRA 342
+I ++ D G Y+C A+N +G+A
Sbjct: 474 IIRNISRSDEGKYTCFAENFMGKA 497
Score = 68.1 bits (159), Expect = 7e-11
Identities = 56/197 (28%), Positives = 79/197 (40%), Gaps = 8/197 (4%)
Query: 170 LVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSR--LGEGPQLQLS 227
L PS++A A G LEC A GNPVP + W +++ S S P LQ+
Sbjct: 236 LFAPSIKARFPAE-TYALVGQQVTLECFAFGNPVPRIKWRKVDGSLSPQWTTAEPTLQIP 294
Query: 228 RLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLAD 287
+ G Y C +N G V + ++ V PE S G C
Sbjct: 295 SVSFEDEGTYECEAENSKGRDTV-QGRIIVQAQPEWLKVISDTEADIGSNLRWGCAAAGK 353
Query: 288 PPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE 347
P V W +N PL++ RV + A L + + ED G Y CVA+N G E
Sbjct: 354 PRPTVRWLRNGEPLASQNRVEVLA----GDLRFSKLSLEDSGMYQCVAENKHGTIYASAE 409
Query: 348 VSGRPGPARFTSPPLAR 364
++ + F P+ R
Sbjct: 410 LAVQALAPDFRLNPVRR 426
Score = 59.7 bits (138), Expect = 2e-08
Identities = 81/333 (24%), Positives = 131/333 (39%), Gaps = 32/333 (9%)
Query: 137 GNTNF-RMIFQDAGDYVCQISDR---VARDQVHTVEVLVPPSVRASPETRHVTARRGGAA 192
G+ F ++ +D+G Y C ++ + V+ L P R +P R + A RGG
Sbjct: 378 GDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAP-DFRLNPVRRLIPAARGGEI 436
Query: 193 VLECRAAGNPVPTVTWHRLND---SSSRLGEGPQ--LQLSRLERHHGGVYACTVDNGVGP 247
++ C+ P V W + + +SSR+ P L + + R G Y C +N +G
Sbjct: 437 LIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGK 496
Query: 248 PVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS--WYQNSFPLSASE 305
T L V +IT+ S G L C DP +++ W + FP+ +
Sbjct: 497 ANSTGI-LSVRDATKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDK 555
Query: 306 -----RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH--VEVSGRPG-PARF 357
R T + + + L I + Q G Y+C+A + A + V V G PG P
Sbjct: 556 PGGHYRRT-NVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGPPGPPGGV 614
Query: 358 TSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAAPAAKGSL 417
+ + S D++ P+ + L R G+W V +G+
Sbjct: 615 VVRDIGDTTIQLSWSRGFDNHSPIAKYTLQART-------PPAGKWKQVRTNPANIEGNA 667
Query: 418 THRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ ++ GL P YE V A N G E S
Sbjct: 668 E---TAQVLGLTPWMDYEFRVIASNILGTGEPS 697
Score = 55.6 bits (128), Expect = 4e-07
Identities = 50/166 (30%), Positives = 70/166 (42%), Gaps = 15/166 (9%)
Query: 193 VLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQL--------SRLERHHGGVYACTVDNG 244
+L CRA +P T W ++N + +L G + QL + + GVY C N
Sbjct: 58 LLACRARASPPATYRW-KMNGTEMKLEPGSRHQLVGGNLVIMNPTKAQDAGVYQCLASNP 116
Query: 245 VGPPVVTEFQLQVLYPPEITVE-RSWVHTGEGFRAELVCTVLADPPA-EVSWYQNSFP-- 300
VG V E L+ + E + E R V EG+ L C A P W N FP
Sbjct: 117 VGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRWLLNEFPNF 176
Query: 301 LSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
+ R +S N L IA D GNYSC+A + + + + V
Sbjct: 177 IPTDGRHFVSQTTGN--LYIARTNASDLGNYSCLATSHMDFSTKSV 220
>BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal)
protein.
Length = 1040
Score = 77.0 bits (181), Expect = 1e-13
Identities = 60/204 (29%), Positives = 88/204 (43%), Gaps = 10/204 (4%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
F+D G Y C+ + RD V ++V A G C AAG P P
Sbjct: 298 FEDEGTYECEAENSKGRDTVQG-RIIVQAQPEWLKVISDTEADIGSNLRWGCAAAGKPRP 356
Query: 205 TVTWHRLND---SSSRLGE-GPQLQLSRLERHHGGVYACTVDNGVGPPVVT-EFQLQVLY 259
TV W R + S +R+ L+ S+L G+Y C +N G + E +Q L
Sbjct: 357 TVRWLRNGEPLASQNRVEVLAGDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALA 416
Query: 260 PP-EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
P + R + G + C A P A V W + + L S RVT++ G TL
Sbjct: 417 PDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDG---TL 473
Query: 319 LIADVQPEDFGNYSCVADNSLGRA 342
+I ++ D G Y+C A+N +G+A
Sbjct: 474 IIRNISRSDEGKYTCFAENFMGKA 497
Score = 68.1 bits (159), Expect = 7e-11
Identities = 56/197 (28%), Positives = 79/197 (40%), Gaps = 8/197 (4%)
Query: 170 LVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSR--LGEGPQLQLS 227
L PS++A A G LEC A GNPVP + W +++ S S P LQ+
Sbjct: 236 LFAPSIKARFPAE-TYALVGQQVTLECFAFGNPVPRIKWRKVDGSLSPQWTTAEPTLQIP 294
Query: 228 RLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLAD 287
+ G Y C +N G V + ++ V PE S G C
Sbjct: 295 SVSFEDEGTYECEAENSKGRDTV-QGRIIVQAQPEWLKVISDTEADIGSNLRWGCAAAGK 353
Query: 288 PPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE 347
P V W +N PL++ RV + A L + + ED G Y CVA+N G E
Sbjct: 354 PRPTVRWLRNGEPLASQNRVEVLA----GDLRFSKLSLEDSGMYQCVAENKHGTIYASAE 409
Query: 348 VSGRPGPARFTSPPLAR 364
++ + F P+ R
Sbjct: 410 LAVQALAPDFRLNPVRR 426
Score = 59.7 bits (138), Expect = 2e-08
Identities = 81/333 (24%), Positives = 131/333 (39%), Gaps = 32/333 (9%)
Query: 137 GNTNF-RMIFQDAGDYVCQISDR---VARDQVHTVEVLVPPSVRASPETRHVTARRGGAA 192
G+ F ++ +D+G Y C ++ + V+ L P R +P R + A RGG
Sbjct: 378 GDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAP-DFRLNPVRRLIPAARGGEI 436
Query: 193 VLECRAAGNPVPTVTWHRLND---SSSRLGEGPQ--LQLSRLERHHGGVYACTVDNGVGP 247
++ C+ P V W + + +SSR+ P L + + R G Y C +N +G
Sbjct: 437 LIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGK 496
Query: 248 PVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS--WYQNSFPLSASE 305
T L V +IT+ S G L C DP +++ W + FP+ +
Sbjct: 497 ANSTGI-LSVRDATKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDK 555
Query: 306 -----RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH--VEVSGRPG-PARF 357
R T + + + L I + Q G Y+C+A + A + V V G PG P
Sbjct: 556 PGGHYRRT-NVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGPPGPPGGV 614
Query: 358 TSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAAPAAKGSL 417
+ + S D++ P+ + L R G+W V +G+
Sbjct: 615 VVRDIGDTTIQLSWSRGFDNHSPIAKYTLQART-------PPAGKWKQVRTNPANIEGNA 667
Query: 418 THRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ ++ GL P YE V A N G E S
Sbjct: 668 E---TAQVLGLTPWMDYEFRVIASNILGTGEPS 697
Score = 55.6 bits (128), Expect = 4e-07
Identities = 50/166 (30%), Positives = 70/166 (42%), Gaps = 15/166 (9%)
Query: 193 VLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQL--------SRLERHHGGVYACTVDNG 244
+L CRA +P T W ++N + +L G + QL + + GVY C N
Sbjct: 58 LLACRARASPPATYRW-KMNGTEMKLEPGSRHQLVGGNLVIMNPTKAQDAGVYQCLASNP 116
Query: 245 VGPPVVTEFQLQVLYPPEITVE-RSWVHTGEGFRAELVCTVLADPPA-EVSWYQNSFP-- 300
VG V E L+ + E + E R V EG+ L C A P W N FP
Sbjct: 117 VGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRWLLNEFPNF 176
Query: 301 LSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
+ R +S N L IA D GNYSC+A + + + + V
Sbjct: 177 IPTDGRHFVSQTTGN--LYIARTNASDLGNYSCLATSHMDFSTKSV 220
>AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal)
protein.
Length = 1040
Score = 77.0 bits (181), Expect = 1e-13
Identities = 60/204 (29%), Positives = 88/204 (43%), Gaps = 10/204 (4%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
F+D G Y C+ + RD V ++V A G C AAG P P
Sbjct: 298 FEDEGTYECEAENSKGRDTVQG-RIIVQAQPEWLKVISDTEADIGSNLRWGCAAAGKPRP 356
Query: 205 TVTWHRLND---SSSRLGE-GPQLQLSRLERHHGGVYACTVDNGVGPPVVT-EFQLQVLY 259
TV W R + S +R+ L+ S+L G+Y C +N G + E +Q L
Sbjct: 357 TVRWLRNGEPLASQNRVEVLAGDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALA 416
Query: 260 PP-EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
P + R + G + C A P A V W + + L S RVT++ G TL
Sbjct: 417 PDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDG---TL 473
Query: 319 LIADVQPEDFGNYSCVADNSLGRA 342
+I ++ D G Y+C A+N +G+A
Sbjct: 474 IIRNISRSDEGKYTCFAENFMGKA 497
Score = 68.1 bits (159), Expect = 7e-11
Identities = 56/197 (28%), Positives = 79/197 (40%), Gaps = 8/197 (4%)
Query: 170 LVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSR--LGEGPQLQLS 227
L PS++A A G LEC A GNPVP + W +++ S S P LQ+
Sbjct: 236 LFAPSIKARFPAE-TYALVGQQVTLECFAFGNPVPRIKWRKVDGSLSPQWTTAEPTLQIP 294
Query: 228 RLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLAD 287
+ G Y C +N G V + ++ V PE S G C
Sbjct: 295 SVSFEDEGTYECEAENSKGRDTV-QGRIIVQAQPEWLKVISDTEADIGSNLRWGCAAAGK 353
Query: 288 PPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE 347
P V W +N PL++ RV + A L + + ED G Y CVA+N G E
Sbjct: 354 PRPTVRWLRNGEPLASQNRVEVLA----GDLRFSKLSLEDSGMYQCVAENKHGTIYASAE 409
Query: 348 VSGRPGPARFTSPPLAR 364
++ + F P+ R
Sbjct: 410 LAVQALAPDFRLNPVRR 426
Score = 59.7 bits (138), Expect = 2e-08
Identities = 81/333 (24%), Positives = 131/333 (39%), Gaps = 32/333 (9%)
Query: 137 GNTNF-RMIFQDAGDYVCQISDR---VARDQVHTVEVLVPPSVRASPETRHVTARRGGAA 192
G+ F ++ +D+G Y C ++ + V+ L P R +P R + A RGG
Sbjct: 378 GDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAP-DFRLNPVRRLIPAARGGEI 436
Query: 193 VLECRAAGNPVPTVTWHRLND---SSSRLGEGPQ--LQLSRLERHHGGVYACTVDNGVGP 247
++ C+ P V W + + +SSR+ P L + + R G Y C +N +G
Sbjct: 437 LIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGK 496
Query: 248 PVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS--WYQNSFPLSASE 305
T L V +IT+ S G L C DP +++ W + FP+ +
Sbjct: 497 ANSTGI-LSVRDATKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDK 555
Query: 306 -----RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH--VEVSGRPG-PARF 357
R T + + + L I + Q G Y+C+A + A + V V G PG P
Sbjct: 556 PGGHYRRT-NVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGPPGPPGGV 614
Query: 358 TSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAAPAAKGSL 417
+ + S D++ P+ + L R G+W V +G+
Sbjct: 615 VVRDIGDTTIQLSWSRGFDNHSPIAKYTLQART-------PPAGKWKQVRTNPANIEGNA 667
Query: 418 THRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ ++ GL P YE V A N G E S
Sbjct: 668 E---TAQVLGLTPWMDYEFRVIASNILGTGEPS 697
Score = 55.6 bits (128), Expect = 4e-07
Identities = 50/166 (30%), Positives = 70/166 (42%), Gaps = 15/166 (9%)
Query: 193 VLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQL--------SRLERHHGGVYACTVDNG 244
+L CRA +P T W ++N + +L G + QL + + GVY C N
Sbjct: 58 LLACRARASPPATYRW-KMNGTEMKLEPGSRHQLVGGNLVIMNPTKAQDAGVYQCLASNP 116
Query: 245 VGPPVVTEFQLQVLYPPEITVE-RSWVHTGEGFRAELVCTVLADPPA-EVSWYQNSFP-- 300
VG V E L+ + E + E R V EG+ L C A P W N FP
Sbjct: 117 VGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRWLLNEFPNF 176
Query: 301 LSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
+ R +S N L IA D GNYSC+A + + + + V
Sbjct: 177 IPTDGRHFVSQTTGN--LYIARTNASDLGNYSCLATSHMDFSTKSV 220
>AL049553-2|CAI20461.1| 957|Homo sapiens MAM domain containing
glycosylphosphatidylinositol anchor 1 protein.
Length = 957
Score = 77.0 bits (181), Expect = 1e-13
Identities = 51/169 (30%), Positives = 81/169 (47%), Gaps = 17/169 (10%)
Query: 182 RHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSS-RLGE----GPQLQLSRLERHHGGV 236
R T R G +L+C G+P P V W + S+S + E L++ R+ R GG
Sbjct: 46 RVYTIREGDTLMLQCLVTGHPRPQVRWTKTAGSASDKFQETSVFNETLRIERIARTQGGR 105
Query: 237 YACTVDNGVGPPVVTEFQLQVLY--PPEITVERSWVHTGEGFRAE----LVCTVLADPPA 290
Y C +NGVG P + ++ V Y P +TV ++ F E L CTV ++PPA
Sbjct: 106 YYCKAENGVGVPAIKSIRVDVQYLDEPMLTVHQTVSDVRGNFYQEKTVFLRCTVNSNPPA 165
Query: 291 EVSWYQNSFPLSASE------RVTMSARGSNHTLLIADVQPEDFGNYSC 333
W + S LS S+ + +G L + +++P+D+ +Y+C
Sbjct: 166 RFIWKRGSDTLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTC 214
Score = 71.7 bits (168), Expect = 5e-12
Identities = 79/279 (28%), Positives = 108/279 (38%), Gaps = 32/279 (11%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEV-----LVPPSVRASPETRHVTARRGGAAVLECRAA 199
F D G Y+C S A +VEV VPP++ VT R G A L+C
Sbjct: 407 FSDYGTYLCMASFPGAPVPDLSVEVNISSETVPPTISVPKGRAVVTVREGSPAELQCEVR 466
Query: 200 GNPVPTVTWHRLNDSSSRLGEG--------PQLQLSRLERHHGGVYACTVD--NGVG-PP 248
G P P V W R++ ++ L G +L+L R+ R G Y C NG P
Sbjct: 467 GKPRPPVLWSRVDKEAALLPSGLPLEETPDGKLRLERVSRDMSGTYRCQTARYNGFNVRP 526
Query: 249 VVTEFQLQVL--YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS---WYQNSFPLSA 303
+ QL V PPE+ V G L C++L P ++ W L
Sbjct: 527 REAQVQLNVQSPVPPEVEPSSQDVRQALGRPVLLRCSLLRGSPQRIASAVWRFKGQLLPP 586
Query: 304 SERVTMSARGSNHTLLIAD-VQPEDFGNYSCVADNSLGRARRHVEVSGRP-GPARFTSPP 361
V +A +H L D V + G+Y C N +G A +VS + P + P
Sbjct: 587 PPVVPAAAEAPDHAELRLDAVTRDSSGSYECSVSNDVGSAACLFQVSAKAYSPEFYFDTP 646
Query: 362 LARAPH------SYTLSFA---VDSYPPLDELRLLYRQL 391
H SY L + D+ P+ RL RQL
Sbjct: 647 NPTRSHKLSKNYSYVLQWTQREPDAVDPVLNYRLSIRQL 685
Score = 53.2 bits (122), Expect = 2e-06
Identities = 54/214 (25%), Positives = 87/214 (40%), Gaps = 27/214 (12%)
Query: 146 QDAGDYVCQISDRVA---RDQVHTVEVL---VPPSVRASPETRHVTARRGGAAVLECR-A 198
QD Y CQ+S R D+ T + PP+++ S V G ++C
Sbjct: 207 QDYASYTCQVSVRNVCGIPDKAITFRLTNTTAPPALKLSVNETLVV-NPGENVTVQCLLT 265
Query: 199 AGNPVPTVTW-HRLNDSS-SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
G+P+P + W H L +G L + ++ G Y CT N VG P L
Sbjct: 266 GGDPLPQLQWSHGPGPLPLGALAQGGTLSIPSVQARDSGYYNCTATNNVGNPAKKTVNLL 325
Query: 257 V--------LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS--WYQNSFPLSASER 306
V P++ E + G+ + L C V A P +V+ W++N P S+R
Sbjct: 326 VRSMKNATFQITPDVIKESENIQLGQDLK--LSCHVDAVPQEKVTYQWFKNGKPARMSKR 383
Query: 307 VTMSAR-----GSNHTLLIADVQPEDFGNYSCVA 335
+ ++ +L + D+ D+G Y C+A
Sbjct: 384 LLVTRNDPELPAVTSSLELIDLHFSDYGTYLCMA 417
Score = 38.3 bits (85), Expect = 0.062
Identities = 38/129 (29%), Positives = 51/129 (39%), Gaps = 14/129 (10%)
Query: 219 GEGPQLQLSRLERHHGGVYACTVD--NGVG-PPVVTEFQL-QVLYPPEITV---ERSWVH 271
GE L+L L Y C V N G P F+L PP + + E V+
Sbjct: 194 GETKVLKLKNLRPQDYASYTCQVSVRNVCGIPDKAITFRLTNTTAPPALKLSVNETLVVN 253
Query: 272 TGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNY 331
GE + + T DP ++ W PL + A TL I VQ D G Y
Sbjct: 254 PGENVTVQCLLTG-GDPLPQLQWSHGPGPLP------LGALAQGGTLSIPSVQARDSGYY 306
Query: 332 SCVADNSLG 340
+C A N++G
Sbjct: 307 NCTATNNVG 315
>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
Length = 1496
Score = 76.2 bits (179), Expect = 3e-13
Identities = 60/224 (26%), Positives = 93/224 (41%), Gaps = 19/224 (8%)
Query: 130 RITSEQHGNTNFRMIFQ-DAGDYVCQISDRVARDQVHTVEVLVP---PSVRASPETRHVT 185
R+ G + + Q D+G+Y C ++ + D VH ++ P +P+ R V
Sbjct: 405 RVNITPSGGLYIQNVVQGDSGEYACSATNNI--DSVHATAFIIVQALPQFTVTPQDRVVI 462
Query: 186 ARRGGAAVLECRAAGNPVPTVTWHRLNDSSSR------LGEGPQLQLSRLERHHGGVYAC 239
G +C A GNP P + W + S L G L++S + H G Y C
Sbjct: 463 --EGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGT-LRISGVALHDQGQYEC 519
Query: 240 TVDNGVGPP-VVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS 298
N +G VV +Q P S G +L C+ +P ++W ++
Sbjct: 520 QAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDG 579
Query: 299 FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
++ S + +S G L I DV P D G Y CVA N++G A
Sbjct: 580 VQVTESGKFHISPEGF---LTINDVGPADAGRYECVARNTIGSA 620
Score = 65.3 bits (152), Expect = 5e-10
Identities = 51/180 (28%), Positives = 73/180 (40%), Gaps = 20/180 (11%)
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-------DSSSRLGEGPQLQ 225
P + + P+ VT+ G CRA GNP P + W R N DS L + L
Sbjct: 263 PRITSEPQDADVTS--GNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLM 320
Query: 226 LSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE-----ITVERSWVHTGEGFRAEL 280
+ + G+Y C N G E L+ P I + + V GE E
Sbjct: 321 IQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLE- 379
Query: 281 VCTVLADPPAEVSWYQ-NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
C+ PP +SW + + PL RV ++ G L I +V D G Y+C A N++
Sbjct: 380 -CSATGHPPPRISWTRGDRTPLPVDPRVNITPSGG---LYIQNVVQGDSGEYACSATNNI 435
Score = 64.1 bits (149), Expect = 1e-09
Identities = 55/197 (27%), Positives = 82/197 (41%), Gaps = 15/197 (7%)
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDS----SSRLGEGPQ--LQL 226
P+ P+ V G + LEC A G+P P ++W R + + R+ P L +
Sbjct: 359 PTFVIQPQNTEVLV--GESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYI 416
Query: 227 SRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLA 286
+ + G YAC+ N + T F + V P+ TV EG + C
Sbjct: 417 QNVVQGDSGEYACSATNNIDSVHATAFII-VQALPQFTVTPQDRVVIEGQTVDFQCEAKG 475
Query: 287 DPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRAR--R 344
+PP ++W + LS R + + G TL I+ V D G Y C A N +G +
Sbjct: 476 NPPPVIAWTKGGSQLSVDRRHLVLSSG---TLRISGVALHDQGQYECQAVNIIGSQKVVA 532
Query: 345 HVEVSGRPGPARFTSPP 361
H+ V R P F S P
Sbjct: 533 HLTVQPRVTPV-FASIP 548
Score = 40.3 bits (90), Expect = 0.015
Identities = 32/126 (25%), Positives = 45/126 (35%), Gaps = 7/126 (5%)
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P IT E G C +P E+ W +N+ LS ++ TL+I
Sbjct: 263 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDG-TLMI 321
Query: 321 ADVQPEDFGNYSCVADNSLGRARRH---VEVSGRPGPARFTSPPL---ARAPHSYTLSFA 374
+ Q D G Y C+A N G + + G P F P S TL +
Sbjct: 322 QNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECS 381
Query: 375 VDSYPP 380
+PP
Sbjct: 382 ATGHPP 387
>BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein.
Length = 722
Score = 76.2 bits (179), Expect = 3e-13
Identities = 60/224 (26%), Positives = 93/224 (41%), Gaps = 19/224 (8%)
Query: 130 RITSEQHGNTNFRMIFQ-DAGDYVCQISDRVARDQVHTVEVLVP---PSVRASPETRHVT 185
R+ G + + Q D+G+Y C ++ + D VH ++ P +P+ R V
Sbjct: 383 RVNITPSGGLYIQNVVQGDSGEYACSATNNI--DSVHATAFIIVQALPQFTVTPQDRVVI 440
Query: 186 ARRGGAAVLECRAAGNPVPTVTWHRLNDSSSR------LGEGPQLQLSRLERHHGGVYAC 239
G +C A GNP P + W + S L G L++S + H G Y C
Sbjct: 441 --EGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGT-LRISGVALHDQGQYEC 497
Query: 240 TVDNGVGPP-VVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS 298
N +G VV +Q P S G +L C+ +P ++W ++
Sbjct: 498 QAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDG 557
Query: 299 FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
++ S + +S G L I DV P D G Y CVA N++G A
Sbjct: 558 VQVTESGKFHISPEGF---LTINDVGPADAGRYECVARNTIGSA 598
Score = 65.3 bits (152), Expect = 5e-10
Identities = 51/180 (28%), Positives = 73/180 (40%), Gaps = 20/180 (11%)
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-------DSSSRLGEGPQLQ 225
P + + P+ VT+ G CRA GNP P + W R N DS L + L
Sbjct: 241 PRITSEPQDADVTS--GNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLM 298
Query: 226 LSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE-----ITVERSWVHTGEGFRAEL 280
+ + G+Y C N G E L+ P I + + V GE E
Sbjct: 299 IQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLE- 357
Query: 281 VCTVLADPPAEVSWYQ-NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
C+ PP +SW + + PL RV ++ G L I +V D G Y+C A N++
Sbjct: 358 -CSATGHPPPRISWTRGDRTPLPVDPRVNITPSGG---LYIQNVVQGDSGEYACSATNNI 413
Score = 64.1 bits (149), Expect = 1e-09
Identities = 55/197 (27%), Positives = 82/197 (41%), Gaps = 15/197 (7%)
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDS----SSRLGEGPQ--LQL 226
P+ P+ V G + LEC A G+P P ++W R + + R+ P L +
Sbjct: 337 PTFVIQPQNTEVLV--GESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYI 394
Query: 227 SRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLA 286
+ + G YAC+ N + T F + V P+ TV EG + C
Sbjct: 395 QNVVQGDSGEYACSATNNIDSVHATAFII-VQALPQFTVTPQDRVVIEGQTVDFQCEAKG 453
Query: 287 DPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRAR--R 344
+PP ++W + LS R + + G TL I+ V D G Y C A N +G +
Sbjct: 454 NPPPVIAWTKGGSQLSVDRRHLVLSSG---TLRISGVALHDQGQYECQAVNIIGSQKVVA 510
Query: 345 HVEVSGRPGPARFTSPP 361
H+ V R P F S P
Sbjct: 511 HLTVQPRVTPV-FASIP 526
Score = 40.3 bits (90), Expect = 0.015
Identities = 32/126 (25%), Positives = 45/126 (35%), Gaps = 7/126 (5%)
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P IT E G C +P E+ W +N+ LS ++ TL+I
Sbjct: 241 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDG-TLMI 299
Query: 321 ADVQPEDFGNYSCVADNSLGRARRH---VEVSGRPGPARFTSPPL---ARAPHSYTLSFA 374
+ Q D G Y C+A N G + + G P F P S TL +
Sbjct: 300 QNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECS 359
Query: 375 VDSYPP 380
+PP
Sbjct: 360 ATGHPP 365
>AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated
antigen MG50 protein.
Length = 1496
Score = 76.2 bits (179), Expect = 3e-13
Identities = 60/224 (26%), Positives = 93/224 (41%), Gaps = 19/224 (8%)
Query: 130 RITSEQHGNTNFRMIFQ-DAGDYVCQISDRVARDQVHTVEVLVP---PSVRASPETRHVT 185
R+ G + + Q D+G+Y C ++ + D VH ++ P +P+ R V
Sbjct: 405 RVNITPSGGLYIQNVVQGDSGEYACSATNNI--DSVHATAFIIVQALPQFTVTPQDRVVI 462
Query: 186 ARRGGAAVLECRAAGNPVPTVTWHRLNDSSSR------LGEGPQLQLSRLERHHGGVYAC 239
G +C A GNP P + W + S L G L++S + H G Y C
Sbjct: 463 --EGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGT-LRISGVALHDQGQYEC 519
Query: 240 TVDNGVGPP-VVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS 298
N +G VV +Q P S G +L C+ +P ++W ++
Sbjct: 520 QAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDG 579
Query: 299 FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
++ S + +S G L I DV P D G Y CVA N++G A
Sbjct: 580 VQVTESGKFHISPEGF---LTINDVGPADAGRYECVARNTIGSA 620
Score = 65.3 bits (152), Expect = 5e-10
Identities = 51/180 (28%), Positives = 73/180 (40%), Gaps = 20/180 (11%)
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-------DSSSRLGEGPQLQ 225
P + + P+ VT+ G CRA GNP P + W R N DS L + L
Sbjct: 263 PRITSEPQDADVTS--GNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLM 320
Query: 226 LSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE-----ITVERSWVHTGEGFRAEL 280
+ + G+Y C N G E L+ P I + + V GE E
Sbjct: 321 IQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLE- 379
Query: 281 VCTVLADPPAEVSWYQ-NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
C+ PP +SW + + PL RV ++ G L I +V D G Y+C A N++
Sbjct: 380 -CSATGHPPPRISWTRGDRTPLPVDPRVNITPSGG---LYIQNVVQGDSGEYACSATNNI 435
Score = 64.1 bits (149), Expect = 1e-09
Identities = 55/197 (27%), Positives = 82/197 (41%), Gaps = 15/197 (7%)
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDS----SSRLGEGPQ--LQL 226
P+ P+ V G + LEC A G+P P ++W R + + R+ P L +
Sbjct: 359 PTFVIQPQNTEVLV--GESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYI 416
Query: 227 SRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLA 286
+ + G YAC+ N + T F + V P+ TV EG + C
Sbjct: 417 QNVVQGDSGEYACSATNNIDSVHATAFII-VQALPQFTVTPQDRVVIEGQTVDFQCEAKG 475
Query: 287 DPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRAR--R 344
+PP ++W + LS R + + G TL I+ V D G Y C A N +G +
Sbjct: 476 NPPPVIAWTKGGSQLSVDRRHLVLSSG---TLRISGVALHDQGQYECQAVNIIGSQKVVA 532
Query: 345 HVEVSGRPGPARFTSPP 361
H+ V R P F S P
Sbjct: 533 HLTVQPRVTPV-FASIP 548
Score = 40.3 bits (90), Expect = 0.015
Identities = 32/126 (25%), Positives = 45/126 (35%), Gaps = 7/126 (5%)
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P IT E G C +P E+ W +N+ LS ++ TL+I
Sbjct: 263 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDG-TLMI 321
Query: 321 ADVQPEDFGNYSCVADNSLGRARRH---VEVSGRPGPARFTSPPL---ARAPHSYTLSFA 374
+ Q D G Y C+A N G + + G P F P S TL +
Sbjct: 322 QNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECS 381
Query: 375 VDSYPP 380
+PP
Sbjct: 382 ATGHPP 387
>AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein 3
protein.
Length = 1386
Score = 75.8 bits (178), Expect = 3e-13
Identities = 67/240 (27%), Positives = 98/240 (40%), Gaps = 15/240 (6%)
Query: 147 DAGDYVCQISDRV--ARDQVHTVEVLV-PPSVRASPETRHVTARRGGAAVLEC-RAAGNP 202
D G Y C + + A + ++EV V R SP +V G AVLEC G+P
Sbjct: 137 DEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPG--NVVVAVGEPAVLECVPPRGHP 194
Query: 203 VPTVTWH----RLNDSSSRLG-EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P+V+W RL + R+ G +L +S + G+Y C N G ++ V
Sbjct: 195 EPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLKSDAGMYVCVASNMAGERESAAAEVMV 254
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
L P +C V DPP + W + L S +H+
Sbjct: 255 LERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGELPTGRYEIRS----DHS 310
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTLSFAVDS 377
L I V ED G Y+CVA+NS+GRA +S P T P A +++F ++
Sbjct: 311 LWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQMAAPGESVAFQCET 370
Score = 66.9 bits (156), Expect = 2e-10
Identities = 88/339 (25%), Positives = 133/339 (39%), Gaps = 46/339 (13%)
Query: 146 QDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G Y C + V R + ++ V VPP + P+ + A G + +C GNP P
Sbjct: 319 EDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQ--MAAPGESVAFQCETKGNPPP 376
Query: 205 TVTWHR------LNDSSS-----RLGEGP--QLQLSRLERHHGGVYACTVDNGVGPPVVT 251
+ W + L S S R P QL ++ ++R G Y C + G ++
Sbjct: 377 AIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYVCQAVSVAGS-ILA 435
Query: 252 EFQLQVL------YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE 305
+ L++ PP I + G L C V +P V W ++ L +
Sbjct: 436 KALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDD 495
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA--------RRHVEVSGRPGPARF 357
+ +N TL IA+VQ D G YSCVA +S G A R VS P P
Sbjct: 496 LQFKTM--ANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLKMREDWGVSPDP-PTEP 552
Query: 358 TSPPLARAP---HSYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGR-WHDVVLAAPAA 413
+SPP A + T + ++ P + I G W V A
Sbjct: 553 SSPPGAPSQPVVTEITKNSITLTWKPNPQTGAAVTSYVIEAFSPAAGNTWRTV------A 606
Query: 414 KGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVSDI 452
G +H + GLQP +Y +V+A +G +E S +
Sbjct: 607 DG--VQLETHTVSGLQPNTIYLFLVRAVGAWGLSEPSPV 643
Score = 47.2 bits (107), Expect = 1e-04
Identities = 60/217 (27%), Positives = 80/217 (36%), Gaps = 27/217 (12%)
Query: 188 RGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEG---------------PQLQLSRLERH 232
RG A L CRA G P P + W++ + + E P++ R R
Sbjct: 77 RGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGALFFPRIVHGRRARP 136
Query: 233 HGGVYACTVDNGVGPPVVTEFQLQV-LYPPEITVERSWVHTGEGFRAELVCT-VLADPPA 290
GVY C N +G L+V + + V G A L C P
Sbjct: 137 DEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVLECVPPRGHPEP 196
Query: 291 EVSWYQNSFPLSASE-RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGR---ARRHV 346
VSW ++ L E R+T+ RG L+++ D G Y CVA N G A V
Sbjct: 197 SVSWRKDGARLKEEEGRITI--RGGK--LMMSHTLKSDAGMYVCVASNMAGERESAAAEV 252
Query: 347 EVSGRPGPAR--FTSPPLARAPHSYTLSFAVDSYPPL 381
V RP R LA AP ++ D P L
Sbjct: 253 MVLERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRL 289
>AL117666-1|CAB56036.1| 483|Homo sapiens hypothetical protein
protein.
Length = 483
Score = 75.8 bits (178), Expect = 3e-13
Identities = 47/170 (27%), Positives = 75/170 (44%), Gaps = 12/170 (7%)
Query: 192 AVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQ---------LSRLERHHGGVYACTVD 242
A LEC A G+P P + W + + ++ ++ ++ GVY+CT
Sbjct: 6 ARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQ 65
Query: 243 NGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLS 302
N G + L VL P + V G L C +PP ++W++ PLS
Sbjct: 66 NSAGS-ISANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLS 124
Query: 303 ASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRP 352
+ER ++ N L++ +V ED G Y+C N+LG R H ++S P
Sbjct: 125 LTERHHLTP--DNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVLP 172
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 9/107 (8%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
DAG Y C + + T+ VL PS+ E R V+ G L+C+A GNP P
Sbjct: 56 DAGVYSCTAQNSAGSISANATLTVLETPSLVVPLEDRVVSV--GETVALQCKATGNPPPR 113
Query: 206 VTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVG 246
+TW + L + + L + + G Y C + N +G
Sbjct: 114 ITWFKGDRPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLG 160
>AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens
cDNA FLJ31982 fis, clone NT2RP7008550, highly similar to
Mus musculus rig-1 protein mRNA. ).
Length = 1034
Score = 75.8 bits (178), Expect = 3e-13
Identities = 67/240 (27%), Positives = 98/240 (40%), Gaps = 15/240 (6%)
Query: 147 DAGDYVCQISDRV--ARDQVHTVEVLV-PPSVRASPETRHVTARRGGAAVLEC-RAAGNP 202
D G Y C + + A + ++EV V R SP +V G AVLEC G+P
Sbjct: 137 DEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPG--NVVVAVGEPAVLECVPPRGHP 194
Query: 203 VPTVTWH----RLNDSSSRLG-EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P+V+W RL + R+ G +L +S + G+Y C N G ++ V
Sbjct: 195 EPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLKSDAGMYVCVASNMAGERESAAAEVMV 254
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
L P +C V DPP + W + L S +H+
Sbjct: 255 LERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGELPTGRYEIRS----DHS 310
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTLSFAVDS 377
L I V ED G Y+CVA+NS+GRA +S P T P A +++F ++
Sbjct: 311 LWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQMAAPGESVAFQCET 370
Score = 66.5 bits (155), Expect = 2e-10
Identities = 88/339 (25%), Positives = 133/339 (39%), Gaps = 46/339 (13%)
Query: 146 QDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G Y C + V R + ++ V VPP + P+ + A G + +C GNP P
Sbjct: 319 EDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQ--MAAPGESVAFQCETKGNPPP 376
Query: 205 TVTWHR------LNDSSS-----RLGEGP--QLQLSRLERHHGGVYACTVDNGVGPPVVT 251
+ W + L S S R P QL ++ ++R G Y C + G ++
Sbjct: 377 AIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYMCQAVSVAGS-ILA 435
Query: 252 EFQLQVL------YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE 305
+ L++ PP I + G L C V +P V W ++ L +
Sbjct: 436 KALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDD 495
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA--------RRHVEVSGRPGPARF 357
+ +N TL IA+VQ D G YSCVA +S G A R VS P P
Sbjct: 496 LQFKTM--ANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLKMREDWGVSPDP-PTEP 552
Query: 358 TSPPLARAP---HSYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGR-WHDVVLAAPAA 413
+SPP A + T + ++ P + I G W V A
Sbjct: 553 SSPPGAPSQPVVTEITKNSITLTWKPNPQTGAAVTSYVIEAFSPAAGNTWRTV------A 606
Query: 414 KGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVSDI 452
G +H + GLQP +Y +V+A +G +E S +
Sbjct: 607 DG--VQLETHTVSGLQPNTIYLFLVRAVGAWGLSEPSPV 643
Score = 47.2 bits (107), Expect = 1e-04
Identities = 60/217 (27%), Positives = 80/217 (36%), Gaps = 27/217 (12%)
Query: 188 RGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEG---------------PQLQLSRLERH 232
RG A L CRA G P P + W++ + + E P++ R R
Sbjct: 77 RGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGALFFPRIVHGRRARP 136
Query: 233 HGGVYACTVDNGVGPPVVTEFQLQV-LYPPEITVERSWVHTGEGFRAELVCT-VLADPPA 290
GVY C N +G L+V + + V G A L C P
Sbjct: 137 DEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVLECVPPRGHPEP 196
Query: 291 EVSWYQNSFPLSASE-RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGR---ARRHV 346
VSW ++ L E R+T+ RG L+++ D G Y CVA N G A V
Sbjct: 197 SVSWRKDGARLKEEEGRITI--RGGK--LMMSHTLKSDAGMYVCVASNMAGERESAAAEV 252
Query: 347 EVSGRPGPAR--FTSPPLARAPHSYTLSFAVDSYPPL 381
V RP R LA AP ++ D P L
Sbjct: 253 MVLERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRL 289
>AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein.
Length = 1250
Score = 75.4 bits (177), Expect = 4e-13
Identities = 59/198 (29%), Positives = 89/198 (44%), Gaps = 15/198 (7%)
Query: 177 ASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLND---SSSRLGEG-PQLQLSRLERH 232
A+PE V + G + V+EC A+ +P P V+W R + S+ + G L ++ +
Sbjct: 248 AAPENTTVVS--GQSVVMECVASADPTPFVSWVRQDGKPISTDVIVLGRTNLLIANAQPW 305
Query: 233 HGGVYACTVDNGVGPPVVTEF-QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAE 291
H GVY C + T +L+VL P IT + A VC +P
Sbjct: 306 HSGVYVCRANKPRTRDFATAAAELRVLAAPAITQAPEALSRTRASTARFVCRASGEPRPA 365
Query: 292 VSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS-- 349
+ W N PL + RV +G +L+I + +D G Y CVA+NS G A ++
Sbjct: 366 LRWLHNGAPLRPNGRV--KVQGGGGSLVITQIGLQDAGYYQCVAENSAGMACAAASLAVV 423
Query: 350 ---GRP-GPARFTSPPLA 363
G P P R T+ PL+
Sbjct: 424 VREGLPSAPTRVTATPLS 441
Score = 44.4 bits (100), Expect = 0.001
Identities = 69/261 (26%), Positives = 92/261 (35%), Gaps = 28/261 (10%)
Query: 149 GDYVCQISDR--VARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
G+Y C V Q V++ PE++ T G A EC G P P +
Sbjct: 117 GNYSCLAHGPLGVLASQTAVVKLATLADFSLHPESQ--TVEENGTARFECHIEGLPAPII 174
Query: 207 TWHR---LNDSSSRLGEGPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP 261
TW + RL P LQ+ ++ G Y C N E L V +
Sbjct: 175 TWEKDQVTLPEEPRLIVLPNGVLQILDVQESDAGPYRCVATNSARQHFSQEALLSVAHRG 234
Query: 262 EITVERSW----VHTGE------GFRAELVCTVLADPPAEVSWY-QNSFPLSASERVTMS 310
+ R V E G + C ADP VSW Q+ P+S V +
Sbjct: 235 SLASTRGQDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSWVRQDGKPISTD--VIVL 292
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGR--ARRHVEVSGRPGPARFTSPPLARAPHS 368
R + LLIA+ QP G Y C A+ R A E+ PA +P +
Sbjct: 293 GRTN---LLIANAQPWHSGVYVCRANKPRTRDFATAAAELRVLAAPAITQAPEALSRTRA 349
Query: 369 YTLSFAV-DSYPPLDELRLLY 388
T F S P LR L+
Sbjct: 350 STARFVCRASGEPRPALRWLH 370
>AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens
cDNA FLJ31774 fis, clone NT2RI2008050, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 512
Score = 74.9 bits (176), Expect = 6e-13
Identities = 69/217 (31%), Positives = 95/217 (43%), Gaps = 22/217 (10%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
DAGDY C + R T++V PP P V+ G L C G P PT
Sbjct: 107 DAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPAD--VSMEIGSNVTLPCYVQGYPEPT 164
Query: 206 VTWHRLND-----------SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
+ W RL++ S S+L G L + L G Y C +N G + +E
Sbjct: 165 IKWRRLDNMPIFSRPFSVSSISQLRTG-ALFILNLWASDKGTYICEAENQFG-KIQSETT 222
Query: 255 LQV--LYPPEITVERSWVHTGEGFRAELVCTVLA-DPPAEVSWYQNSFPLSASERVTMSA 311
+ V L P I + S + EG + L CT+LA +P E W +NS L + +T+ +
Sbjct: 223 VTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRS 282
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
GS H I VQ +D G Y+CVA N G + V
Sbjct: 283 DGSLH---IERVQLQDGGEYTCVASNVAGTNNKTTSV 316
Score = 71.7 bits (168), Expect = 5e-12
Identities = 60/213 (28%), Positives = 90/213 (42%), Gaps = 16/213 (7%)
Query: 147 DAGDYVCQISDRVARDQVHT---VEVLVPPSVRASPETRHVTARRGGAAVLECRA-AGNP 202
D G Y+C+ ++ + Q T V LV P + SP +V G L C AGNP
Sbjct: 202 DKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVI--EGQQLTLPCTLLAGNP 259
Query: 203 VPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPP-VVTEFQLQ 256
+P W + L + + L + R++ GG Y C N G T +
Sbjct: 260 IPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH 319
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
VL P I + + T EG L C +P V W + +S S SA G++
Sbjct: 320 VL--PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSS-AKFSA-GADG 375
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+L + E+ G Y C A N+ G A+R V+++
Sbjct: 376 SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLT 408
Score = 64.1 bits (149), Expect = 1e-09
Identities = 61/235 (25%), Positives = 99/235 (42%), Gaps = 21/235 (8%)
Query: 131 ITSEQHGNTNF-RMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRG 189
IT G+ + R+ QD G+Y C ++ VA T V+V + ++ G
Sbjct: 278 ITVRSDGSLHIERVQLQDGGEYTC-VASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEG 336
Query: 190 GAAVLECRAAGNPVPTVTWHR----LNDSSSRLGEGPQLQLSRLER--HHGGVYACTVDN 243
L C+A+GNP P+V W + ++ SS++ G L + G Y CT N
Sbjct: 337 IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 396
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGE--------GFRAELVCTVLADPPAEVSWY 295
G + QL V P + ++ + + G L C V + PP ++W
Sbjct: 397 TAGY-AKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 455
Query: 296 QNSFPLSA-SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
+ + +S S R T GS + I + + D G Y CVA N G + V+++
Sbjct: 456 KETQLISPFSPRHTFLPSGS---MKITETRTSDSGMYLCVATNIAGNVTQAVKLN 507
Score = 58.0 bits (134), Expect = 7e-08
Identities = 61/229 (26%), Positives = 92/229 (40%), Gaps = 14/229 (6%)
Query: 146 QDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAG Y C S+ D Q T+ + P + V G V+EC+ +G P P
Sbjct: 15 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVAL--GDITVMECKTSGIPPP 72
Query: 205 TVTWHRLN---DSSSRLGEGPQLQLSRLERHH---GGVYACTVDNGVGPPVVTEFQLQVL 258
V W + + S+ L P L L +++ G Y C N G + L V
Sbjct: 73 QVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAG-RATGKITLDVG 131
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ-NSFPL-SASERVTMSARGSNH 316
PP E + V G L C V P + W + ++ P+ S V+ ++
Sbjct: 132 SPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG 191
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRH--VEVSGRPGPARFTSPPLA 363
L I ++ D G Y C A+N G+ + V V+G P SP +A
Sbjct: 192 ALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVA 240
Score = 48.4 bits (110), Expect = 6e-05
Identities = 42/168 (25%), Positives = 65/168 (38%), Gaps = 8/168 (4%)
Query: 235 GVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSW 294
G+Y C N G L+ + P++ V +S + G + C PP +V W
Sbjct: 18 GIYGCLASNSAGTDKQNS-TLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKW 76
Query: 295 YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
++ L S + + L I + Q D G+Y+CVA N GRA + + P
Sbjct: 77 FKGDLELRPSTFLIIDPLLG--LLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPP 134
Query: 355 ARFTSPP--LARAPHSYTLSFAVDSYPPLDELRLLYRQLAINESFQQP 400
P + TL V YP E + +R+L F +P
Sbjct: 135 VFIQEPADVSMEIGSNVTLPCYVQGYP---EPTIKWRRLDNMPIFSRP 179
Score = 31.1 bits (67), Expect = 9.4
Identities = 13/32 (40%), Positives = 20/32 (62%)
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRH 345
S+ TL I + P+D G Y C+A NS G +++
Sbjct: 3 SDGTLFIKNAAPKDAGIYGCLASNSAGTDKQN 34
>BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein.
Length = 1551
Score = 74.5 bits (175), Expect = 8e-13
Identities = 64/226 (28%), Positives = 96/226 (42%), Gaps = 17/226 (7%)
Query: 147 DAGDYVCQISDRVARDQVH--TVEV-LVPPSVRASPETRHVTARRGGAAVLECRAA-GNP 202
D G YVC + + H ++EV ++ R +P V G AV+EC+ G+P
Sbjct: 102 DEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVVV--GEPAVMECQPPRGHP 159
Query: 203 VPTVTWHR----LNDSSSRLG-EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
PT++W + L+D R+ G +L ++ + G Y C N VG +L V
Sbjct: 160 EPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTV 219
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
L P S + AE C DP V W ++ L S +HT
Sbjct: 220 LERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRD----DHT 275
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG--PARFTSPP 361
L I V D G+Y+CVA+N +G+A ++ + G P F P
Sbjct: 276 LKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKP 321
Score = 54.8 bits (126), Expect = 7e-07
Identities = 80/340 (23%), Positives = 132/340 (38%), Gaps = 46/340 (13%)
Query: 147 DAGDYVCQISDRVARDQVH---TVEV-LVPPSVRASPETRHVTARRGGAAVLECRAAGNP 202
D G Y C + V + + TV+V PP P + V G +C A GNP
Sbjct: 285 DMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVAL--GRTVTFQCEATGNP 342
Query: 203 VPTVTWHRLN-----------DSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPV 249
P + W R SSSR + + L ++ ++R G Y C N G +
Sbjct: 343 QPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAG-SI 401
Query: 250 VTEFQLQVL-----YPPEITVERSWVHTGEGFRAELV--CTVLADPPAEVSWYQNSFPLS 302
+T+ L+V PP + + + V+ V C P + W ++ +S
Sbjct: 402 ITKAYLEVTDVIADRPPPV-IRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVS 460
Query: 303 ASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA--RRHVEVSGRPGPARFTSP 360
+ + + N L I + D G Y+C+A G A ++EV P + P
Sbjct: 461 TQD--SRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQ---P 515
Query: 361 PLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAA-PAAKGSLTH 419
P P+ L + S P + ++ L+ + ++ A A GS
Sbjct: 516 PRPTDPN---LIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQ 572
Query: 420 RVSHE-------LRGLQPAAVYEAIVQAKNRYGWNEVSDI 452
V+ ++GL+P A+Y +V+A N YG ++ S I
Sbjct: 573 TVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQI 612
Score = 52.8 bits (121), Expect = 3e-06
Identities = 55/193 (28%), Positives = 76/193 (39%), Gaps = 24/193 (12%)
Query: 172 PPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHR--------LNDSSSRLGEGPQ 223
PP + P V+ +G A L C+A G P PT+ W++ +D S P
Sbjct: 28 PPRIVEHPSDLIVS--KGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPS 85
Query: 224 LQLSRLERHHG-------GVYACTVDNGVGPPVVTEFQLQV-LYPPEITVERSWVHTGEG 275
L L HG GVY C N +G V L+V + + S V G
Sbjct: 86 GSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVVVG 145
Query: 276 FRAELVC-TVLADPPAEVSWYQNSFPL-SASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
A + C P +SW ++ PL ER+T+ RG L+I + D G Y C
Sbjct: 146 EPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITI--RGGK--LMITYTRKSDAGKYVC 201
Query: 334 VADNSLGRARRHV 346
V N +G V
Sbjct: 202 VGTNMVGERESEV 214
Score = 41.9 bits (94), Expect = 0.005
Identities = 34/135 (25%), Positives = 55/135 (40%), Gaps = 16/135 (11%)
Query: 126 ETTRRITSEQHGNTNFRMIFQ-DAGDYVCQI----SDRVARDQVHTVEVLV---PPSVRA 177
+++ R + Q G+ + + D G Y+CQ + + + +V+ PP +R
Sbjct: 364 QSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQ 423
Query: 178 SPETRHVTARRGGAAVLECRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLER 231
P + V G VL C A G+PVPT+ W + DS + E LQ+ +
Sbjct: 424 GPVNQTVAV--DGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKL 481
Query: 232 HHGGVYACTVDNGVG 246
G Y C G
Sbjct: 482 GDTGRYTCIASTPSG 496
Score = 31.9 bits (69), Expect = 5.4
Identities = 28/94 (29%), Positives = 36/94 (38%), Gaps = 7/94 (7%)
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR-----G 313
+PP I S + +G A L C P + WY+ + + S R G
Sbjct: 27 FPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSG 86
Query: 314 SNHTLLIADVQPE--DFGNYSCVADNSLGRARRH 345
S L I + D G Y CVA N LG A H
Sbjct: 87 SLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSH 120
>BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein.
Length = 1606
Score = 74.5 bits (175), Expect = 8e-13
Identities = 64/226 (28%), Positives = 96/226 (42%), Gaps = 17/226 (7%)
Query: 147 DAGDYVCQISDRVARDQVH--TVEV-LVPPSVRASPETRHVTARRGGAAVLECRAA-GNP 202
D G YVC + + H ++EV ++ R +P V G AV+EC+ G+P
Sbjct: 102 DEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAV--GEPAVMECQPPRGHP 159
Query: 203 VPTVTWHR----LNDSSSRLG-EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
PT++W + L+D R+ G +L ++ + G Y C N VG +L V
Sbjct: 160 EPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTV 219
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
L P S + AE C DP V W ++ L S +HT
Sbjct: 220 LERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRD----DHT 275
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG--PARFTSPP 361
L I V D G+Y+CVA+N +G+A ++ + G P F P
Sbjct: 276 LKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKP 321
Score = 54.8 bits (126), Expect = 7e-07
Identities = 80/340 (23%), Positives = 132/340 (38%), Gaps = 46/340 (13%)
Query: 147 DAGDYVCQISDRVARDQVH---TVEV-LVPPSVRASPETRHVTARRGGAAVLECRAAGNP 202
D G Y C + V + + TV+V PP P + V G +C A GNP
Sbjct: 285 DMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVAL--GRTVTFQCEATGNP 342
Query: 203 VPTVTWHRLN-----------DSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPV 249
P + W R SSSR + + L ++ ++R G Y C N G +
Sbjct: 343 QPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAG-SI 401
Query: 250 VTEFQLQVL-----YPPEITVERSWVHTGEGFRAELV--CTVLADPPAEVSWYQNSFPLS 302
+T+ L+V PP + + + V+ V C P + W ++ +S
Sbjct: 402 ITKAYLEVTDVIADRPPPV-IRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVS 460
Query: 303 ASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA--RRHVEVSGRPGPARFTSP 360
+ + + N L I + D G Y+C+A G A ++EV P + P
Sbjct: 461 TQD--SRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQ---P 515
Query: 361 PLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAA-PAAKGSLTH 419
P P+ L + S P + ++ L+ + ++ A A GS
Sbjct: 516 PRPTDPN---LIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQ 572
Query: 420 RVSHE-------LRGLQPAAVYEAIVQAKNRYGWNEVSDI 452
V+ ++GL+P A+Y +V+A N YG ++ S I
Sbjct: 573 TVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQI 612
Score = 54.0 bits (124), Expect = 1e-06
Identities = 55/193 (28%), Positives = 76/193 (39%), Gaps = 24/193 (12%)
Query: 172 PPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHR--------LNDSSSRLGEGPQ 223
PP + P V+ +G A L C+A G P PT+ W++ +D S P
Sbjct: 28 PPRIVEHPSDLIVS--KGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPS 85
Query: 224 LQLSRLERHHG-------GVYACTVDNGVGPPVVTEFQLQV-LYPPEITVERSWVHTGEG 275
L L HG GVY C N +G V L+V + + S V G
Sbjct: 86 GSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVG 145
Query: 276 FRAELVC-TVLADPPAEVSWYQNSFPL-SASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
A + C P +SW ++ PL ER+T+ RG L+I + D G Y C
Sbjct: 146 EPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITI--RGGK--LMITYTRKSDAGKYVC 201
Query: 334 VADNSLGRARRHV 346
V N +G V
Sbjct: 202 VGTNMVGERESEV 214
Score = 41.9 bits (94), Expect = 0.005
Identities = 34/135 (25%), Positives = 55/135 (40%), Gaps = 16/135 (11%)
Query: 126 ETTRRITSEQHGNTNFRMIFQ-DAGDYVCQI----SDRVARDQVHTVEVLV---PPSVRA 177
+++ R + Q G+ + + D G Y+CQ + + + +V+ PP +R
Sbjct: 364 QSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQ 423
Query: 178 SPETRHVTARRGGAAVLECRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLER 231
P + V G VL C A G+PVPT+ W + DS + E LQ+ +
Sbjct: 424 GPVNQTVAV--DGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKL 481
Query: 232 HHGGVYACTVDNGVG 246
G Y C G
Sbjct: 482 GDTGRYTCIASTPSG 496
Score = 31.9 bits (69), Expect = 5.4
Identities = 28/94 (29%), Positives = 36/94 (38%), Gaps = 7/94 (7%)
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR-----G 313
+PP I S + +G A L C P + WY+ + + S R G
Sbjct: 27 FPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSG 86
Query: 314 SNHTLLIADVQPE--DFGNYSCVADNSLGRARRH 345
S L I + D G Y CVA N LG A H
Sbjct: 87 SLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSH 120
>BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein.
Length = 1607
Score = 74.5 bits (175), Expect = 8e-13
Identities = 64/226 (28%), Positives = 96/226 (42%), Gaps = 17/226 (7%)
Query: 147 DAGDYVCQISDRVARDQVH--TVEV-LVPPSVRASPETRHVTARRGGAAVLECRAA-GNP 202
D G YVC + + H ++EV ++ R +P V G AV+EC+ G+P
Sbjct: 102 DEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAV--GEPAVMECQPPRGHP 159
Query: 203 VPTVTWHR----LNDSSSRLG-EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
PT++W + L+D R+ G +L ++ + G Y C N VG +L V
Sbjct: 160 EPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTV 219
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
L P S + AE C DP V W ++ L S +HT
Sbjct: 220 LERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRD----DHT 275
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG--PARFTSPP 361
L I V D G+Y+CVA+N +G+A ++ + G P F P
Sbjct: 276 LKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKP 321
Score = 54.8 bits (126), Expect = 7e-07
Identities = 80/340 (23%), Positives = 132/340 (38%), Gaps = 46/340 (13%)
Query: 147 DAGDYVCQISDRVARDQVH---TVEV-LVPPSVRASPETRHVTARRGGAAVLECRAAGNP 202
D G Y C + V + + TV+V PP P + V G +C A GNP
Sbjct: 285 DMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVAL--GRTVTFQCEATGNP 342
Query: 203 VPTVTWHRLN-----------DSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPV 249
P + W R SSSR + + L ++ ++R G Y C N G +
Sbjct: 343 QPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAG-SI 401
Query: 250 VTEFQLQVL-----YPPEITVERSWVHTGEGFRAELV--CTVLADPPAEVSWYQNSFPLS 302
+T+ L+V PP + + + V+ V C P + W ++ +S
Sbjct: 402 ITKAYLEVTDVIADRPPPV-IRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVS 460
Query: 303 ASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA--RRHVEVSGRPGPARFTSP 360
+ + + N L I + D G Y+C+A G A ++EV P + P
Sbjct: 461 TQD--SRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQ---P 515
Query: 361 PLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAA-PAAKGSLTH 419
P P+ L + S P + ++ L+ + ++ A A GS
Sbjct: 516 PRPTDPN---LIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQ 572
Query: 420 RVSHE-------LRGLQPAAVYEAIVQAKNRYGWNEVSDI 452
V+ ++GL+P A+Y +V+A N YG ++ S I
Sbjct: 573 TVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQI 612
Score = 54.0 bits (124), Expect = 1e-06
Identities = 55/193 (28%), Positives = 76/193 (39%), Gaps = 24/193 (12%)
Query: 172 PPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHR--------LNDSSSRLGEGPQ 223
PP + P V+ +G A L C+A G P PT+ W++ +D S P
Sbjct: 28 PPRIVEHPSDLIVS--KGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPS 85
Query: 224 LQLSRLERHHG-------GVYACTVDNGVGPPVVTEFQLQV-LYPPEITVERSWVHTGEG 275
L L HG GVY C N +G V L+V + + S V G
Sbjct: 86 GSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVG 145
Query: 276 FRAELVC-TVLADPPAEVSWYQNSFPL-SASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
A + C P +SW ++ PL ER+T+ RG L+I + D G Y C
Sbjct: 146 EPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITI--RGGK--LMITYTRKSDAGKYVC 201
Query: 334 VADNSLGRARRHV 346
V N +G V
Sbjct: 202 VGTNMVGERESEV 214
Score = 41.9 bits (94), Expect = 0.005
Identities = 34/135 (25%), Positives = 55/135 (40%), Gaps = 16/135 (11%)
Query: 126 ETTRRITSEQHGNTNFRMIFQ-DAGDYVCQI----SDRVARDQVHTVEVLV---PPSVRA 177
+++ R + Q G+ + + D G Y+CQ + + + +V+ PP +R
Sbjct: 364 QSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQ 423
Query: 178 SPETRHVTARRGGAAVLECRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLER 231
P + V G VL C A G+PVPT+ W + DS + E LQ+ +
Sbjct: 424 GPVNQTVAV--DGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKL 481
Query: 232 HHGGVYACTVDNGVG 246
G Y C G
Sbjct: 482 GDTGRYTCIASTPSG 496
Score = 31.9 bits (69), Expect = 5.4
Identities = 28/94 (29%), Positives = 36/94 (38%), Gaps = 7/94 (7%)
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR-----G 313
+PP I S + +G A L C P + WY+ + + S R G
Sbjct: 27 FPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSG 86
Query: 314 SNHTLLIADVQPE--DFGNYSCVADNSLGRARRH 345
S L I + D G Y CVA N LG A H
Sbjct: 87 SLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSH 120
>Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein.
Length = 1018
Score = 74.1 bits (174), Expect = 1e-12
Identities = 75/326 (23%), Positives = 133/326 (40%), Gaps = 27/326 (8%)
Query: 141 FRMIFQDAGDYVCQISDRVARDQVHT-VEVL-VPPSVRASPETRHVTARRGGAAVLECRA 198
+ + F++AG Y C + + +++L + P+ +P + + A +GG ++EC+
Sbjct: 379 YDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKP 438
Query: 199 AGNPVPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
P P +W + +N S + E L+++ + R+ GG+Y C +N G T
Sbjct: 439 KAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTG- 497
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS--WYQNSFPLSASERVTMSA 311
L + P I + G A + C DP +++ W N + + ++
Sbjct: 498 TLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQ 557
Query: 312 RG----SNHTLLIADVQPEDFGNYSCVADNSL--GRARRHVEVSGRPGPARFTSPPLARA 365
R SN LLI + Q + G Y+C A + A + V G PGP RA
Sbjct: 558 RNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRA 617
Query: 366 PH-SYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHE 424
+ T S D++ P+ + + + + ++ W D P +G++ +
Sbjct: 618 TSVALTWSRGSDNHSPISKYTIQTKTILSDD-------WKDAKTDPPIIEGNME---AAR 667
Query: 425 LRGLQPAAVYEAIVQAKNRYGWNEVS 450
L P YE V A N G E S
Sbjct: 668 AVDLIPWMEYEFRVVATNTLGRGEPS 693
Score = 58.8 bits (136), Expect = 4e-08
Identities = 56/184 (30%), Positives = 76/184 (41%), Gaps = 16/184 (8%)
Query: 190 GAAVLECRAAGNPVPTVTWHRLND----SSSRLGE-GPQLQLSRLERHH-GGVYACTVDN 243
G L CRA +P P W N +S R G L ++ ++ G+Y C N
Sbjct: 59 GKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLASN 118
Query: 244 GVGPPVVTEFQLQVLY----PPEITVERSWVHTGEGFRAELVCTVLADPPAEVS--WYQN 297
G TE L Y PPE ER V EG L+C P ++S W N
Sbjct: 119 NYGMVRSTEATLSFGYLDPFPPE---ERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLN 175
Query: 298 SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC-VADNSLGRARRHVEVSGRPGPAR 356
FP+ + +N L IA+V+ D GNYSC V+ S+ ++ + P P R
Sbjct: 176 EFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPER 235
Query: 357 FTSP 360
T P
Sbjct: 236 TTKP 239
Score = 56.4 bits (130), Expect = 2e-07
Identities = 56/234 (23%), Positives = 90/234 (38%), Gaps = 27/234 (11%)
Query: 129 RRITSEQHGNTNFRMI-FQDAGDYVCQISDRVARDQVHTVEV-LVP-PSVRASP------ 179
RR S+ +GN + D G+Y C +S V + + L+P P P
Sbjct: 186 RRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPYPADIV 245
Query: 180 -ETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGE----GPQLQLSRLERHHG 234
+ + V A G LEC A GNPVP + W ++ + E G L++ ++
Sbjct: 246 VQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNIQLEDE 305
Query: 235 GVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSW 294
G+Y C +N G + ++ V PE + G C P + W
Sbjct: 306 GIYECEAENIRGKD-KHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRW 364
Query: 295 YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
+N + E L + DV E+ G Y C+A+N+ G + E+
Sbjct: 365 LKNGYAYHKGE------------LRLYDVTFENAGMYQCIAENTYGAIYANAEL 406
>U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 74.1 bits (174), Expect = 1e-12
Identities = 68/244 (27%), Positives = 102/244 (41%), Gaps = 23/244 (9%)
Query: 147 DAGDYVCQIS-DRVARDQVHTVEVLVP--PSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D G Y C + + + T +++V P + PE V A G A+L C + V
Sbjct: 123 DEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYA--GNGAILNCEVNADLV 180
Query: 204 PTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P V W + L+D +L G L +S GG+Y C V++G P E +L+V
Sbjct: 181 PFVRWEQNRQPLLLDDRVIKLPSG-MLVISNATEGDGGLYRCVVESGGPPKYSDEVELKV 239
Query: 258 LYPPEITVERSWVHTGE------GFRAELVCTVLADPPAEVSWYQNSFPL--SASERVTM 309
L PE+ + ++ G L C P + W +N L +SER+ +
Sbjct: 240 LPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVL 299
Query: 310 SARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSY 369
A GS L I+DV +D G Y C+ADN E++ + P P A S
Sbjct: 300 LAGGS---LEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESM 356
Query: 370 TLSF 373
+ F
Sbjct: 357 DIVF 360
Score = 72.5 bits (170), Expect = 3e-12
Identities = 70/276 (25%), Positives = 108/276 (39%), Gaps = 27/276 (9%)
Query: 189 GGAAVLECRAAGNPVPTVTWHRLND-----SSSRLG--EGPQLQLSRLERHHGGVYACTV 241
G VL C A+G P PT+ W + + SS RL G L++S + G Y C
Sbjct: 263 GQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIA 322
Query: 242 DNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL 301
DNG + + +L V PE + + ++ E C V P V W +N +
Sbjct: 323 DNG-NETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMV 381
Query: 302 SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE-VSGRPGPARFTSP 360
S+ + H L + + D G Y C+A+N +G A+ + + PA T+
Sbjct: 382 IPSDYFKIV---KEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPA--TTG 436
Query: 361 PLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAAPAAKGSLTHR 420
PL AP S + ++L +R A + + V
Sbjct: 437 PLPSAPRDVVASLVSTRF-----IKLTWRTPASDP--HGDNLTYSVFYTKEGIARERVEN 489
Query: 421 VSH------ELRGLQPAAVYEAIVQAKNRYGWNEVS 450
SH ++ L PA VY V A+N++G E S
Sbjct: 490 TSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESS 525
Score = 46.4 bits (105), Expect = 2e-04
Identities = 48/165 (29%), Positives = 69/165 (41%), Gaps = 20/165 (12%)
Query: 188 RGGAAVLECRAAGNPVPTVTWHR-------LNDSSSRLGEGPQLQLSRL--ERHH---GG 235
RG + +L C A P P + W + ++D +L L +S + +H+ G
Sbjct: 66 RGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEG 125
Query: 236 VYACTVD-NGVGPPVVTEFQLQVLYPPEIT--VERSWVHTGEGFRAELVCTVLADPPAEV 292
Y C +G + +L V P T E S V+ G G A L C V AD V
Sbjct: 126 YYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNG--AILNCEVNADLVPFV 183
Query: 293 SWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADN 337
W QN PL +RV G L+I++ D G Y CV ++
Sbjct: 184 RWEQNRQPLLLDDRVIKLPSG---MLVISNATEGDGGLYRCVVES 225
Score = 43.6 bits (98), Expect = 0.002
Identities = 32/109 (29%), Positives = 46/109 (42%), Gaps = 14/109 (12%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPE----TRHVTARRGGAAVLECRAAGNP 202
DAG Y C +A + T+E +V+A PE ++ A V EC G P
Sbjct: 314 DAGTYFC-----IADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKP 368
Query: 203 VPTVTWHRLND-----SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVG 246
PTV W + D ++ + LQ+ L + G Y C +N VG
Sbjct: 369 TPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVG 417
>U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor
protein.
Length = 1007
Score = 74.1 bits (174), Expect = 1e-12
Identities = 75/326 (23%), Positives = 133/326 (40%), Gaps = 27/326 (8%)
Query: 141 FRMIFQDAGDYVCQISDRVARDQVHT-VEVL-VPPSVRASPETRHVTARRGGAAVLECRA 198
+ + F++AG Y C + + +++L + P+ +P + + A +GG ++EC+
Sbjct: 368 YDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKP 427
Query: 199 AGNPVPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
P P +W + +N S + E L+++ + R+ GG+Y C +N G T
Sbjct: 428 KAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTG- 486
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS--WYQNSFPLSASERVTMSA 311
L + P I + G A + C DP +++ W N + + ++
Sbjct: 487 TLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQ 546
Query: 312 RG----SNHTLLIADVQPEDFGNYSCVADNSL--GRARRHVEVSGRPGPARFTSPPLARA 365
R SN LLI + Q + G Y+C A + A + V G PGP RA
Sbjct: 547 RNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRA 606
Query: 366 PH-SYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHE 424
+ T S D++ P+ + + + + ++ W D P +G++ +
Sbjct: 607 TSVALTWSRGSDNHSPISKYTIQTKTILSDD-------WKDAKTDPPIIEGNME---AAR 656
Query: 425 LRGLQPAAVYEAIVQAKNRYGWNEVS 450
L P YE V A N G E S
Sbjct: 657 AVDLIPWMEYEFRVVATNTLGRGEPS 682
Score = 58.8 bits (136), Expect = 4e-08
Identities = 56/184 (30%), Positives = 76/184 (41%), Gaps = 16/184 (8%)
Query: 190 GAAVLECRAAGNPVPTVTWHRLND----SSSRLGE-GPQLQLSRLERHH-GGVYACTVDN 243
G L CRA +P P W N +S R G L ++ ++ G+Y C N
Sbjct: 48 GKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLASN 107
Query: 244 GVGPPVVTEFQLQVLY----PPEITVERSWVHTGEGFRAELVCTVLADPPAEVS--WYQN 297
G TE L Y PPE ER V EG L+C P ++S W N
Sbjct: 108 NYGMVRSTEATLSFGYLDPFPPE---ERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLN 164
Query: 298 SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC-VADNSLGRARRHVEVSGRPGPAR 356
FP+ + +N L IA+V+ D GNYSC V+ S+ ++ + P P R
Sbjct: 165 EFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPER 224
Query: 357 FTSP 360
T P
Sbjct: 225 TTKP 228
Score = 56.4 bits (130), Expect = 2e-07
Identities = 56/234 (23%), Positives = 90/234 (38%), Gaps = 27/234 (11%)
Query: 129 RRITSEQHGNTNFRMI-FQDAGDYVCQISDRVARDQVHTVEV-LVP-PSVRASP------ 179
RR S+ +GN + D G+Y C +S V + + L+P P P
Sbjct: 175 RRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPYPADIV 234
Query: 180 -ETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGE----GPQLQLSRLERHHG 234
+ + V A G LEC A GNPVP + W ++ + E G L++ ++
Sbjct: 235 VQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNIQLEDE 294
Query: 235 GVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSW 294
G+Y C +N G + ++ V PE + G C P + W
Sbjct: 295 GIYECEAENIRGKD-KHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRW 353
Query: 295 YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
+N + E L + DV E+ G Y C+A+N+ G + E+
Sbjct: 354 LKNGYAYHKGE------------LRLYDVTFENAGMYQCIAENTYGAIYANAEL 395
>U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor
protein.
Length = 1018
Score = 74.1 bits (174), Expect = 1e-12
Identities = 75/326 (23%), Positives = 133/326 (40%), Gaps = 27/326 (8%)
Query: 141 FRMIFQDAGDYVCQISDRVARDQVHT-VEVL-VPPSVRASPETRHVTARRGGAAVLECRA 198
+ + F++AG Y C + + +++L + P+ +P + + A +GG ++EC+
Sbjct: 379 YDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKP 438
Query: 199 AGNPVPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
P P +W + +N S + E L+++ + R+ GG+Y C +N G T
Sbjct: 439 KAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTG- 497
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS--WYQNSFPLSASERVTMSA 311
L + P I + G A + C DP +++ W N + + ++
Sbjct: 498 TLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQ 557
Query: 312 RG----SNHTLLIADVQPEDFGNYSCVADNSL--GRARRHVEVSGRPGPARFTSPPLARA 365
R SN LLI + Q + G Y+C A + A + V G PGP RA
Sbjct: 558 RNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRA 617
Query: 366 PH-SYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHE 424
+ T S D++ P+ + + + + ++ W D P +G++ +
Sbjct: 618 TSVALTWSRGSDNHSPISKYTIQTKTILSDD-------WKDAKTDPPIIEGNME---AAR 667
Query: 425 LRGLQPAAVYEAIVQAKNRYGWNEVS 450
L P YE V A N G E S
Sbjct: 668 AVDLIPWMEYEFRVVATNTLGRGEPS 693
Score = 58.8 bits (136), Expect = 4e-08
Identities = 56/184 (30%), Positives = 76/184 (41%), Gaps = 16/184 (8%)
Query: 190 GAAVLECRAAGNPVPTVTWHRLND----SSSRLGE-GPQLQLSRLERHH-GGVYACTVDN 243
G L CRA +P P W N +S R G L ++ ++ G+Y C N
Sbjct: 59 GKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLASN 118
Query: 244 GVGPPVVTEFQLQVLY----PPEITVERSWVHTGEGFRAELVCTVLADPPAEVS--WYQN 297
G TE L Y PPE ER V EG L+C P ++S W N
Sbjct: 119 NYGMVRSTEATLSFGYLDPFPPE---ERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLN 175
Query: 298 SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC-VADNSLGRARRHVEVSGRPGPAR 356
FP+ + +N L IA+V+ D GNYSC V+ S+ ++ + P P R
Sbjct: 176 EFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPER 235
Query: 357 FTSP 360
T P
Sbjct: 236 TTKP 239
Score = 56.4 bits (130), Expect = 2e-07
Identities = 56/234 (23%), Positives = 90/234 (38%), Gaps = 27/234 (11%)
Query: 129 RRITSEQHGNTNFRMI-FQDAGDYVCQISDRVARDQVHTVEV-LVP-PSVRASP------ 179
RR S+ +GN + D G+Y C +S V + + L+P P P
Sbjct: 186 RRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPYPADIV 245
Query: 180 -ETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGE----GPQLQLSRLERHHG 234
+ + V A G LEC A GNPVP + W ++ + E G L++ ++
Sbjct: 246 VQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNIQLEDE 305
Query: 235 GVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSW 294
G+Y C +N G + ++ V PE + G C P + W
Sbjct: 306 GIYECEAENIRGKD-KHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRW 364
Query: 295 YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
+N + E L + DV E+ G Y C+A+N+ G + E+
Sbjct: 365 LKNGYAYHKGE------------LRLYDVTFENAGMYQCIAENTYGAIYANAEL 406
>AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 74.1 bits (174), Expect = 1e-12
Identities = 70/240 (29%), Positives = 103/240 (42%), Gaps = 31/240 (12%)
Query: 121 HTNVWETTRRITSEQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPE 180
H RR+ +Q G T DAGDY C+ + ++H E P + A +
Sbjct: 1029 HVEAKGCRRRLVVQQAGKT-------DAGDYSCEARGQRVSFRLHITE---PKMMFAKEQ 1078
Query: 181 TRH--VTARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRLG---EG--PQLQLSRLE 230
+ H V A G +A+L C A VTW++ SSS++G +G +L L +
Sbjct: 1079 SVHNEVQAEAGASAMLSCEVA-QAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAG 1137
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTG----EGFRAELVCTVLA 286
+ G Y+C G V F L + P + + VH G A L C V A
Sbjct: 1138 KADAGEYSCEAG---GQRV--SFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEV-A 1191
Query: 287 DPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
P EV+WY++ LS+S +V M +G L++ V D G YSC A + H+
Sbjct: 1192 QPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHI 1251
Score = 62.5 bits (145), Expect = 3e-09
Identities = 62/221 (28%), Positives = 91/221 (41%), Gaps = 29/221 (13%)
Query: 128 TRRITSEQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRH--VT 185
TRR+ +Q G DAG+Y C+ + Q+H E P +V A + H V
Sbjct: 1220 TRRLVVQQVGKA-------DAGEYSCEAGGQRVSFQLHITE---PKAVFAKEQLVHNEVR 1269
Query: 186 ARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRL-----GEGPQLQLSRLERHHGGVY 237
G +A L C A VTW++ SSS++ G QL + + + G Y
Sbjct: 1270 TEAGASATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEY 1328
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTV---LADPPAEVSW 294
C G + F L V P + + H A + T+ +A EV+W
Sbjct: 1329 TCEAG---GQRL--SFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTW 1383
Query: 295 YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
Y++ LS+S +V M A G L++ D G YSC A
Sbjct: 1384 YKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA 1424
Score = 59.7 bits (138), Expect = 2e-08
Identities = 55/198 (27%), Positives = 85/198 (42%), Gaps = 16/198 (8%)
Query: 148 AGDYVCQISDRVARDQVHTVEVLVPPSVRAS--PETRHVTARRGGAAVLECRAAGNPVPT 205
AG+Y C+ + +H E P +V A P +R V A G +A L C A
Sbjct: 1509 AGEYSCEAGSQRLSFHLHVAE---PKAVFAKEQPASREVQAEAGTSATLSCEVA-QAQTE 1564
Query: 206 VTWHR----LNDSSS----RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
VTW++ L+ SS +G +L + + G Y+C + + + +V
Sbjct: 1565 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKAGDQRLSFHLHVAEPKV 1624
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
++ E R V G A L C V A EV+WY++ LS+S +V + A G
Sbjct: 1625 VFAKEQPAHRE-VQAEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRR 1682
Query: 318 LLIADVQPEDFGNYSCVA 335
L++ + G YSC A
Sbjct: 1683 LVVQQAGQAEAGEYSCEA 1700
Score = 58.4 bits (135), Expect = 5e-08
Identities = 58/208 (27%), Positives = 80/208 (38%), Gaps = 20/208 (9%)
Query: 152 VCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRL 211
+C I R+A + V PP E TA G L CR G P P ++W++
Sbjct: 5999 ICGIQQRLA------LPVWRPPDFEE--ELADCTAELGETVKLACRVTGTPKPVISWYKD 6050
Query: 212 N-----DSSSRLGEGPQ----LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE 262
D L E P L L L G Y C + G T ++ V PP
Sbjct: 6051 GKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAG-NCSTLGKILVQVPPR 6109
Query: 263 ITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERV-TMS-ARGSNHTLLI 320
+ EG A+ CT+ P ++ WY++ L+ + T+S R L+I
Sbjct: 6110 FVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVI 6169
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEV 348
ED G Y C N LG AR E+
Sbjct: 6170 RAASKEDLGLYECELVNRLGSARASAEL 6197
Score = 57.6 bits (133), Expect = 9e-08
Identities = 64/216 (29%), Positives = 88/216 (40%), Gaps = 26/216 (12%)
Query: 146 QDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPET--RHVTARRGGAAVLECRAAGNP 202
QD G Y C RV D V + V P V A + R + A G +A L C A
Sbjct: 863 QDEGTYSC----RVGEDSVDFRLRVSEPKVVFAKEQLARRKLQAEAGASATLSCEVA-QA 917
Query: 203 VPTVTWHR----LNDSSSRLGEGP----QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
VTW++ L+ SS E +L + + + G Y+C G + F
Sbjct: 918 QTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAG---GQRL--SFH 972
Query: 255 LQVLYPPEI----TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
L V P + V S V G A L C V A EV WY++ LS+S +V +
Sbjct: 973 LDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEV-AQAQTEVMWYKDGKKLSSSLKVHVE 1031
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
A+G L++ D G+YSC A R H+
Sbjct: 1032 AKGCRRRLVVQQAGKTDAGDYSCEARGQRVSFRLHI 1067
Score = 56.0 bits (129), Expect = 3e-07
Identities = 52/197 (26%), Positives = 80/197 (40%), Gaps = 15/197 (7%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG+Y C+ D+ +H E V + P R V A G +A L C A V
Sbjct: 1600 DAGEYSCKAGDQRLSFHLHVAEPKVV-FAKEQPAHREVQAEAGASATLSCEVA-QAQTEV 1657
Query: 207 TWHR----LNDSSS----RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
TW++ L+ SS +G +L + + + G Y+C G + Q+ L
Sbjct: 1658 TWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSCEAG---GQQLSFRLQVAEL 1714
Query: 259 YPP--EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
P E R + E L T+ A V+W ++ + S+R +++G H
Sbjct: 1715 EPQISERPCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTH 1774
Query: 317 TLLIADVQPEDFGNYSC 333
TL + Q D YSC
Sbjct: 1775 TLTVHGAQVLDSAIYSC 1791
Score = 55.6 bits (128), Expect = 4e-07
Identities = 57/210 (27%), Positives = 82/210 (39%), Gaps = 18/210 (8%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D G+Y C R T+ V P V P + + A G A L+C + P TV
Sbjct: 3866 DTGEYSCVCGQE--RTSA-TLTVRAPQPVFREP-LQSLQAEEGSTATLQCELS-EPTATV 3920
Query: 207 TWHR----LNDSSSR----LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W + L + R G +L L L+R G Y CT + +T V
Sbjct: 3921 VWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTCTCGSQATSATLTVTAAPVR 3980
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
+ E+ + EG A L C L+ A V W + S L + M G+ L
Sbjct: 3981 FLRELQHQE----VDEGGTAHLCCE-LSRAGASVEWRKGSLQLFPCAKYQMVQDGAAAEL 4035
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEV 348
L+ V+ ED G+Y+C ++ A V V
Sbjct: 4036 LVRGVEQEDAGDYTCDTGHTQSMASLSVRV 4065
Score = 54.4 bits (125), Expect = 9e-07
Identities = 55/201 (27%), Positives = 84/201 (41%), Gaps = 13/201 (6%)
Query: 183 HVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVY----- 237
+V A GG A+ EC+ + V TW L+D E ++ H +
Sbjct: 4348 NVEALEGGEALFECQLSQPEVAAHTW-LLDDEPVHTSENAEVVFFENGLRHLLLLKNLRP 4406
Query: 238 --ACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVL-ADPPAEVSW 294
+C V G V + F + EI G +A CT+ A P E SW
Sbjct: 4407 QDSCRVTFLAGDMVTSAFLTVRGWRLEILEPLKNAAVRAGAQACFTCTLSEAVPVGEASW 4466
Query: 295 YQNSFPLSASERV-TMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
Y N + + T++A GS+H LL+ QP G + +++ AR + V G P
Sbjct: 4467 YINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACRDAVASAR--LTVLGLPD 4524
Query: 354 PARFTSPPLARAPHSYTLSFA 374
P + +AR+ H+ TLS+A
Sbjct: 4525 PPE-DAEVVARSSHTVTLSWA 4544
Score = 54.0 bits (124), Expect = 1e-06
Identities = 50/174 (28%), Positives = 73/174 (41%), Gaps = 14/174 (8%)
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHR----LNDSSSR-----LGEGPQLQLSRLERHHG 234
V A GG A EC + V V W++ L S R +G +L + + R
Sbjct: 807 VDAVAGGPAQFECETSEAHVH-VHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDE 865
Query: 235 GVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSW 294
G Y+C V + + +V++ E R + G A L C V A EV+W
Sbjct: 866 GTYSCRVGEDSVDFRLRVSEPKVVFAKEQLARRK-LQAEAGASATLSCEV-AQAQTEVTW 923
Query: 295 YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
Y++ LS+S +V M A G L++ D G YSC A R H++V
Sbjct: 924 YKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQ--RLSFHLDV 975
Score = 54.0 bits (124), Expect = 1e-06
Identities = 53/208 (25%), Positives = 84/208 (40%), Gaps = 12/208 (5%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D G+Y C+ + + E V + P R V A+ G + L C A V
Sbjct: 1416 DTGEYSCEAGGQRLSFSLDVAEPKVV-FAKEQPVHREVQAQAGASTTLSCEVA-QAQTEV 1473
Query: 207 TWHR----LNDSSS----RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W++ L+ SS +G +L + + + G Y+C + + + + +
Sbjct: 1474 MWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEAGSQRLSFHLHVAEPKAV 1533
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
+ E R V G A L C V A EV+WY++ LS+S +V M A G L
Sbjct: 1534 FAKEQPASRE-VQAEAGTSATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRL 1591
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHV 346
++ + D G YSC A + HV
Sbjct: 1592 VVQEAGQADAGEYSCKAGDQRLSFHLHV 1619
Score = 52.0 bits (119), Expect = 5e-06
Identities = 49/171 (28%), Positives = 67/171 (39%), Gaps = 18/171 (10%)
Query: 189 GGAAVLECRAAGNPVPTVTWHR-----LNDSSSRLG-EGPQLQLSRLERHHG--GVYACT 240
G A L C+ GNP P V+W + + RL +G +L+ L+ G G Y C
Sbjct: 24 GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCR 83
Query: 241 VDNGVGPPVVTEFQLQV-------LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS 293
N +G LQV P + + + EG A C V P VS
Sbjct: 84 ARNAIG-EAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVS 142
Query: 294 WYQNSFPLSASE--RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
W ++ L + RV + G L I +P D G Y A+N LG A
Sbjct: 143 WSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAA 193
Score = 51.2 bits (117), Expect = 8e-06
Identities = 53/211 (25%), Positives = 85/211 (40%), Gaps = 17/211 (8%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+DAG+YVC+ D Q+ V VP V+ V A GG A +C + + V
Sbjct: 1873 EDAGEYVCESRDDHTSAQL---TVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDV-A 1928
Query: 206 VTWHR----LNDSS----SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V W R L S S+ G L +S L G + + + V
Sbjct: 1929 VVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVREAPV 1988
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
L+ ++ E V E+ T P E+ W +N+ L+ + V + A G+ H
Sbjct: 1989 LFKKKL--EPQTVEERSSVTLEVELT---RPWPELRWTRNATALAPGKNVEIHAEGARHR 2043
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
L++ +V D G + C + +A+ VE+
Sbjct: 2044 LVLHNVGFADRGFFGCETPDDKTQAKLTVEM 2074
Score = 50.8 bits (116), Expect = 1e-05
Identities = 63/284 (22%), Positives = 111/284 (39%), Gaps = 28/284 (9%)
Query: 102 TIYENSETSVALAILGATGHTNVWETTRRITSE-------QHGNTNF--RMIF---QDAG 149
T+ E ++ + G VW+ ++ +E + NF +++F D G
Sbjct: 248 TVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRG 307
Query: 150 DYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWH 209
Y C S+ V + + V+ P+V + + R +A C P W
Sbjct: 308 LYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVP-QPSTEAAWF 366
Query: 210 RLND---SSSRLG---EGPQLQLS--RLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP 261
+ +S++ G EG + +L+ + VY C G V E +Q
Sbjct: 367 KEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEG--SRTVAELAVQGNLLR 424
Query: 262 EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIA 321
++ ++ V G+ + C LA P V W +N + A RV +SA G+ HTL I+
Sbjct: 425 KLP-RKTAVRVGD---TAMFCVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTIS 480
Query: 322 DVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARA 365
ED G + +A + + V +P P + P+ +A
Sbjct: 481 QCCLEDVGQVAFMAGDCQTSTQFCVSAPRKP-PLQPPVDPVVKA 523
Score = 50.0 bits (114), Expect = 2e-05
Identities = 52/195 (26%), Positives = 78/195 (40%), Gaps = 19/195 (9%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG+Y C + + TV L R + ++ AR G AVL+C + V
Sbjct: 3778 DAGEYSC-VCGQERTSATLTVRAL---PARFIEDVKNQEAREGATAVLQCELS--KAAPV 3831
Query: 207 TWH------RLNDSSSRLGEGP--QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W R D S +G +LQ+ L G Y+C +T Q +
Sbjct: 3832 EWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQPV 3891
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
+ + + EG A L C L++P A V W + L A+ R +G L
Sbjct: 3892 FREPLQS----LQAEEGSTATLQCE-LSEPTATVVWSKGGLQLQANGRREPRLQGCTAEL 3946
Query: 319 LIADVQPEDFGNYSC 333
++ D+Q ED G Y+C
Sbjct: 3947 VLQDLQREDTGEYTC 3961
Score = 47.6 bits (108), Expect = 1e-04
Identities = 50/199 (25%), Positives = 78/199 (39%), Gaps = 20/199 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+D G+Y C + T+ V P VR E +H GG A L C + +
Sbjct: 3954 EDTGEYTCTCGSQATSA---TLTVTAAP-VRFLRELQHQEVDEGGTAHLCCELS-RAGAS 4008
Query: 206 VTWHR--------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V W + + G +L + +E+ G Y C D G + + L V
Sbjct: 4009 VEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTC--DTGHTQSMAS---LSV 4063
Query: 258 LYP-PEITVERSWVHTGEGFRAELVCTVL-ADPPAEVSWYQNSFPLSASERVTMSARGSN 315
P P+ + G A L C + A+ A V W + L A + M ++G+
Sbjct: 4064 RVPRPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGAT 4123
Query: 316 HTLLIADVQPEDFGNYSCV 334
LLI ++ +D G Y+CV
Sbjct: 4124 RELLIHQLEAKDTGEYACV 4142
Score = 46.8 bits (106), Expect = 2e-04
Identities = 41/142 (28%), Positives = 59/142 (41%), Gaps = 9/142 (6%)
Query: 272 TGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNY 331
TG ++ ++ P V WY++ PLS SE+ MS G L I + P D G Y
Sbjct: 2479 TGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVY 2538
Query: 332 SCVADNSLGRARRHVEVSGRPGPARFTSP-PLARAPHSYTLSFAVDSYPPLDELRLLYRQ 390
C A G A EV+ T P A A SF+ + +E+
Sbjct: 2539 RCQA----GSAHSSTEVTVEAREVTVTGPLQDAEATEEGWASFSCELSHEDEEVEWSLNG 2594
Query: 391 LAI-NESFQQ---PGRWHDVVL 408
+ + N+SF + GR H +VL
Sbjct: 2595 MPLYNDSFHEISHKGRRHTLVL 2616
Score = 46.8 bits (106), Expect = 2e-04
Identities = 54/219 (24%), Positives = 88/219 (40%), Gaps = 24/219 (10%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG+Y+C + + T+ L R + ++ AR G AVL+C N V
Sbjct: 3514 DAGEYLC-VCGQERTSATLTIRAL---PARFIEDVKNQEAREGATAVLQCEL--NSAAPV 3567
Query: 207 TWHR----LND----SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W + L D S + G +LQ+ L G Y+C ++T L +
Sbjct: 3568 EWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRALPIK 3627
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
+ + E + EG A L C + P E W++ L +R ++ G+ L
Sbjct: 3628 FTEGLRNEEAT----EGATAVLRCELSKMAPVE--WWKGHETLRDGDRHSLRQDGARCEL 3681
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF 357
I + ED G Y C+ G+ R ++ R P++F
Sbjct: 3682 QIRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKF 3716
Score = 46.4 bits (105), Expect = 2e-04
Identities = 58/220 (26%), Positives = 82/220 (37%), Gaps = 23/220 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
QD+G Y C+ + V V P VR + + GGAA L C + P
Sbjct: 3160 QDSGRYKCEAGGACSSS---IVRVHARP-VRFQEALKDLEVLEGGAATLRCVLSSVAAP- 3214
Query: 206 VTWH------RLNDSSSRLGEGPQLQL--SRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V W R D S EG L+L L G Y+C+ + +T L
Sbjct: 3215 VKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSCSFGDQTTSATLTVTALPA 3274
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
+ ++ + + EG A L C + P E W + S L +R + G+
Sbjct: 3275 QFIGKLRNKEAT----EGATATLRCELSKAAPVE--WRKGSETLRDGDRYCLRQDGAMCE 3328
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF 357
L I + D YSCV G R ++ RP PA F
Sbjct: 3329 LQIRGLAMVDAAEYSCVC----GEERTSASLTIRPMPAHF 3364
Score = 46.0 bits (104), Expect = 3e-04
Identities = 44/172 (25%), Positives = 68/172 (39%), Gaps = 14/172 (8%)
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHR---LNDSSSR--LGEGPQ---- 223
P+ S TR T G A L C G P P W + L R + E Q
Sbjct: 236 PASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFV 295
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSW--VHTGEGFRAELV 281
L++ ++ G+Y CT N VG + L V+ P + ++ + E A +
Sbjct: 296 LKILFCKQSDRGLYTCTASNLVGQTYSS--VLVVVREPAVPFKKRLQDLEVREKESATFL 353
Query: 282 CTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
C V P E +W++ L AS + + G+ L + +V +D Y C
Sbjct: 354 CEV-PQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYIC 404
Score = 44.8 bits (101), Expect = 7e-04
Identities = 36/144 (25%), Positives = 59/144 (40%), Gaps = 8/144 (5%)
Query: 210 RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP----PEITV 265
R + + LG G +++L +E+ V C + PVV L L P
Sbjct: 5074 RFQEMFATLGIGVEIKL--VEQGPRRVEMC-ISKETPAPVVPPEPLPSLLTSDAAPVFLT 5130
Query: 266 ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA-RGSNHTLLIADVQ 324
E +G+ C V P V W+++ L + ++ + H L+I V
Sbjct: 5131 ELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVV 5190
Query: 325 PEDFGNYSCVADNSLGRARRHVEV 348
P D G Y C+A+NS+G + E+
Sbjct: 5191 PADMGVYRCLAENSMGVSSTKAEL 5214
Score = 44.4 bits (100), Expect = 0.001
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 261 PEITVERSWVHTGEGFR-AELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
P++ E + G R A+ V P + W+++ PL+AS + M+ + HTL
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLE 5319
Query: 320 IADVQPEDFGNYSCVADNSLGRA 342
I V ED G Y+ N++G A
Sbjct: 5320 IISVTREDSGQYAAYISNAMGAA 5342
Score = 44.0 bits (99), Expect = 0.001
Identities = 51/212 (24%), Positives = 81/212 (38%), Gaps = 19/212 (8%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+DAG+Y C++ + +H E + + E ++ G AV C+ +P T
Sbjct: 2891 KDAGEYTCEVEASKSTASLHVEE----KANCFTEELTNLQVEEKGTAVFTCKTE-HPAAT 2945
Query: 206 VTWHR----LNDSS----SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
VTW + L S S+ G +L +S LE+ Y C + + +V
Sbjct: 2946 VTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRV 3005
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR-GSNH 316
I + V EG A C + V W+ + PL A+E + A+ G H
Sbjct: 3006 ----HIIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYH 3061
Query: 317 TLLIADVQPEDFGN-YSCVADNSLGRARRHVE 347
L + + +D G Y D A R E
Sbjct: 3062 VLTLRQLALKDSGTIYFEAGDQRASAALRVTE 3093
Score = 43.6 bits (98), Expect = 0.002
Identities = 56/214 (26%), Positives = 82/214 (38%), Gaps = 20/214 (9%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGN 201
R++ DAG Y CQ + +V TVE V + + A G A C +
Sbjct: 2529 RLMPADAGVYRCQAGSAHSSTEV-TVEAR---EVTVTGPLQDAEATEEGWASFSCELSHE 2584
Query: 202 PVPTVTWHR-----LNDSS---SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
V W NDS S G L L ++R G+ + V T
Sbjct: 2585 D-EEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRAS-----SLKVSTSA 2638
Query: 254 QLQVLYPPEITVER-SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
+L+V P + ++ + E L C V +DP A V W ++ L S++
Sbjct: 2639 RLEVRVKPVVFLKALDDLSAEERGTLALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHT 2697
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
L++ DV PED G Y+C + RAR V
Sbjct: 2698 AGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRV 2731
Score = 41.9 bits (94), Expect = 0.005
Identities = 74/273 (27%), Positives = 101/273 (36%), Gaps = 36/273 (13%)
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLG-------EGP--QLQLSRLERHHG 234
V GG L C + V W R ++ R+G EGP L + L
Sbjct: 1818 VCGELGGTVTLACELSP-ACAEVVW-RCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDA 1875
Query: 235 GVYACTVDNGVGPPVVTEFQLQVLYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEV 292
G Y C + T QL V P + S V EG A C V A V
Sbjct: 1876 GEYVCESRDDH-----TSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDVAVV 1930
Query: 293 SWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRP 352
W+++ L SE+ +S G++H+L I+D+ ED G + A+ + A V R
Sbjct: 1931 -WFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRV----RE 1985
Query: 353 GPARF---TSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLA 409
P F P S TL V+ P ELR A+ PG+ +V +
Sbjct: 1986 APVLFKKKLEPQTVEERSSVTLE--VELTRPWPELRWTRNATAL-----APGK--NVEIH 2036
Query: 410 APAAKGSLT-HRVSHELRGLQPAAVYEAIVQAK 441
A A+ L H V RG + QAK
Sbjct: 2037 AEGARHRLVLHNVGFADRGFFGCETPDDKTQAK 2069
Score = 40.7 bits (91), Expect = 0.012
Identities = 49/206 (23%), Positives = 79/206 (38%), Gaps = 18/206 (8%)
Query: 136 HGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLE 195
H T ++ +D+G + D+ A + E PSV S E T G L
Sbjct: 3061 HVLTLRQLALKDSGTIYFEAGDQRASAALRVTE---KPSV-FSRELTDATITEGEDLTLV 3116
Query: 196 CRAAGNPVPTVTWHR----LNDSS----SRLGEGPQLQLSRLERHHGGVYACTVDNGVGP 247
C + +P V W + L S+ S G QL ++ G Y C
Sbjct: 3117 CETSTCDIP-VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSS 3175
Query: 248 PVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERV 307
+V V + + + EG A L C VL+ A V W + L ++
Sbjct: 3176 SIVRVHARPVRFQEALKD----LEVLEGGAATLRC-VLSSVAAPVKWCYGNNVLRPGDKY 3230
Query: 308 TMSARGSNHTLLIADVQPEDFGNYSC 333
++ G+ L++ +++P+D G YSC
Sbjct: 3231 SLRQEGAMLELVVRNLRPQDSGRYSC 3256
Score = 40.7 bits (91), Expect = 0.012
Identities = 54/220 (24%), Positives = 85/220 (38%), Gaps = 24/220 (10%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG+Y C + + TV+ L + + R+ A G A+L C + V V
Sbjct: 3426 DAGEYSCVCGEERTSATL-TVKAL---PAKFTEGLRNEEAVEGATAMLWCELS--KVAPV 3479
Query: 207 TWHR----LNDSSSRL----GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W + L D + G +LQ+ L G Y C +T L
Sbjct: 3480 EWRKGPENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATLTIRALPAR 3539
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
+ ++ + + EG A L C + + P E W + S L +R ++ G+ L
Sbjct: 3540 FIEDVKNQEA----REGATAVLQCELNSAAPVE--WRKGSETLRDGDRYSLRQDGTKCEL 3593
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFT 358
I + D G YSCV G+ R ++ R P +FT
Sbjct: 3594 QIRGLAMADTGEYSCVC----GQERTSAMLTVRALPIKFT 3629
Score = 40.3 bits (90), Expect = 0.015
Identities = 48/198 (24%), Positives = 76/198 (38%), Gaps = 16/198 (8%)
Query: 143 MIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAA-GN 201
++ +DAG+Y+C + + TV + + R+ A G A L C +
Sbjct: 3686 LVAEDAGEYLCMCG-KERTSAMLTVRAMPSKFIEG---LRNEEATEGDTATLWCELSKAA 3741
Query: 202 PVPTVTWH---RLNDSSSRLGEGP--QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
PV H R D S +G +LQ+ L G Y+C +T L
Sbjct: 3742 PVEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSCVCGQERTSATLTVRALP 3801
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
+ ++ + + EG A L C + P E W + S L +R ++ G+
Sbjct: 3802 ARFIEDVKNQEA----REGATAVLQCELSKAAPVE--WRKGSETLRGGDRYSLRQDGTRC 3855
Query: 317 TLLIADVQPEDFGNYSCV 334
L I + D G YSCV
Sbjct: 3856 ELQIHGLSVADTGEYSCV 3873
Score = 39.5 bits (88), Expect = 0.027
Identities = 29/117 (24%), Positives = 45/117 (38%), Gaps = 18/117 (15%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRH-------VTARRGGAAVLECRAA 199
D+G YVC+ + + + V + V + + H + R G A CR
Sbjct: 76 DSGQYVCRARNAIG-EAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVG 134
Query: 200 GNPVPTVTW----HRLNDSS------SRLGEGPQLQLSRLERHHGGVYACTVDNGVG 246
G+P P V+W RL + LGE L++ GG Y +N +G
Sbjct: 135 GSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLG 191
Score = 39.5 bits (88), Expect = 0.027
Identities = 39/128 (30%), Positives = 51/128 (39%), Gaps = 9/128 (7%)
Query: 219 GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWV--HTGEGF 276
G +L + +LE G YAC V G T L+V PE+T+ R V
Sbjct: 4121 GATRELLIHQLEAKDTGEYAC-VTGGQK----TAASLRVT-EPEVTIVRGLVDAEVTADE 4174
Query: 277 RAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR-GSNHTLLIADVQPEDFGNYSCVA 335
E C V V W PL ++E ++ R G HTL + V PED G S
Sbjct: 4175 DVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHL 4234
Query: 336 DNSLGRAR 343
N A+
Sbjct: 4235 GNHASSAQ 4242
Score = 38.3 bits (85), Expect = 0.062
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
Query: 285 LADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
L+D A V+W ++ LS + + A LL+ DV +D G Y CV+ GR
Sbjct: 730 LSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRG--GRIAY 787
Query: 345 HVEVSG 350
+ V G
Sbjct: 788 QLSVQG 793
Score = 36.7 bits (81), Expect = 0.19
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 3/83 (3%)
Query: 265 VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQ 324
+E WV GE EL C L+ V W ++ + S++ + G+ L+I
Sbjct: 2833 LEDQWVAPGED--VELRCE-LSRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGAS 2889
Query: 325 PEDFGNYSCVADNSLGRARRHVE 347
+D G Y+C + S A HVE
Sbjct: 2890 LKDAGEYTCEVEASKSTASLHVE 2912
Score = 36.3 bits (80), Expect = 0.25
Identities = 55/218 (25%), Positives = 80/218 (36%), Gaps = 26/218 (11%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+ Y C I +R Q+ ++ V + V + G +A CR + V
Sbjct: 2981 DSDTYTCDIGQAQSRAQL----LVQGRRVHIIEDLEDVDVQEGSSATFRCRISPANYEPV 3036
Query: 207 TW---------HRLNDSSSRLGEGPQLQLSRLE-RHHGGVYACTVDNGVGPPV-VTEFQL 255
W + LN+ ++ G L L +L + G +Y D + VTE
Sbjct: 3037 HWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSGTIYFEAGDQRASAALRVTE--- 3093
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVC-TVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
P + E + EG LVC T D P V W ++ L S R +S G
Sbjct: 3094 ---KPSVFSRELTDATITEGEDLTLVCETSTCDIP--VCWTKDGKTLRGSARCQLSHEGH 3148
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRP 352
LLI +D G Y C A + + V V RP
Sbjct: 3149 RAQLLITGATLQDSGRYKCEAGGACSSS--IVRVHARP 3184
Score = 35.9 bits (79), Expect = 0.33
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
E R L C V + A+V W++ S L + + + G L+I+DV ED Y+C
Sbjct: 2303 EKHRGVLECQV-SRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTC 2361
Query: 334 VADNSLGRARRHVE 347
A + A+ VE
Sbjct: 2362 DAGDVKTSAQFFVE 2375
Score = 35.5 bits (78), Expect = 0.44
Identities = 56/214 (26%), Positives = 90/214 (42%), Gaps = 18/214 (8%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
F D G + C+ D + ++ TVE+ VR + V AR G A +E + + V
Sbjct: 2051 FADRGFFGCETPDDKTQAKL-TVEMR---QVRLVRGLQAVEAREQGTATMEVQLSHADVD 2106
Query: 205 TVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACT--VDNGV----GPPVVTEFQLQVL 258
+W R R +GP L+ H + D+G+ V T +L V
Sbjct: 2107 G-SWTR---DGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAEGVHTSARLVVT 2162
Query: 259 -YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
P + V T E + L C L+ P +V W ++ L A + + ++A+G+ +
Sbjct: 2163 ELPVSFSRPLQDVVTTEKEKVTLECE-LSRPNVDVRWLKDGVELRAGKTMAIAAQGACRS 2221
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR 351
L I + D G Y C A ++ A V+V GR
Sbjct: 2222 LTIYRCEFADQGVYVCDAHDAQSSA--SVKVQGR 2253
Score = 35.1 bits (77), Expect = 0.58
Identities = 16/47 (34%), Positives = 28/47 (59%), Gaps = 2/47 (4%)
Query: 308 TMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA--RRHVEVSGRP 352
T+++ H+L++ DV + G Y+C+A N+ G+A + VSG P
Sbjct: 5424 TVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLP 5470
Score = 34.3 bits (75), Expect = 1.0
Identities = 47/198 (23%), Positives = 74/198 (37%), Gaps = 20/198 (10%)
Query: 146 QDAGDYVC-------QISDRVARDQVHTVEVLVPPSVRASPETRH-VTARRGGAAVLECR 197
+D G+Y C S RV +V V LV V A + R GA ++
Sbjct: 4134 KDTGEYACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQWC 4193
Query: 198 AAGNPVPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
G P+ + + + + + R G L+L + G + + N +T
Sbjct: 4194 LQGLPLQS---NEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLT------ 4244
Query: 258 LYPPEITVERSW--VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA-RGS 314
+ PE+T+ V EG A C + E W PL A+E ++ +G+
Sbjct: 4245 VRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGT 4304
Query: 315 NHTLLIADVQPEDFGNYS 332
H L + V ED G S
Sbjct: 4305 LHLLTLHKVTLEDAGTVS 4322
Score = 33.9 bits (74), Expect = 1.3
Identities = 52/221 (23%), Positives = 80/221 (36%), Gaps = 24/221 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
QD+G Y C D+ T+ V P+ + + R+ A G A L C +
Sbjct: 3249 QDSGRYSCSFGDQTTSA---TLTVTALPA-QFIGKLRNKEATEGATATLRCELS--KAAP 3302
Query: 206 VTWHR----LNDSSSRL----GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V W + L D G +LQ+ L Y+C +T +
Sbjct: 3303 VEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLTIRPMPA 3362
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
+ + + S EG A L C + P E W + L +R ++ G+
Sbjct: 3363 HFIGRLRHQESI----EGATATLRCELSKAAPVE--WRKGRESLRDGDRHSLRQDGAVCE 3416
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFT 358
L I + D G YSCV G R ++ + PA+FT
Sbjct: 3417 LQICGLAVADAGEYSCVC----GEERTSATLTVKALPAKFT 3453
Score = 33.1 bits (72), Expect = 2.3
Identities = 27/93 (29%), Positives = 34/93 (36%), Gaps = 16/93 (17%)
Query: 168 EVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGP----- 222
E LVPP + + V ++G + + G PVPTV W R L GP
Sbjct: 5366 EQLVPPRMLERFTPKKV--KKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGY 5423
Query: 223 ---------QLQLSRLERHHGGVYACTVDNGVG 246
L L + R H G Y C N G
Sbjct: 5424 TVASSAQQHSLVLLDVGRQHQGTYTCIASNAAG 5456
>AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 74.1 bits (174), Expect = 1e-12
Identities = 70/240 (29%), Positives = 103/240 (42%), Gaps = 31/240 (12%)
Query: 121 HTNVWETTRRITSEQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPE 180
H RR+ +Q G T DAGDY C+ + ++H E P + A +
Sbjct: 1029 HVEAKGCRRRLVVQQAGKT-------DAGDYSCEARGQRVSFRLHITE---PKMMFAKEQ 1078
Query: 181 TRH--VTARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRLG---EG--PQLQLSRLE 230
+ H V A G +A+L C A VTW++ SSS++G +G +L L +
Sbjct: 1079 SVHNEVQAEAGASAMLSCEVA-QAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAG 1137
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTG----EGFRAELVCTVLA 286
+ G Y+C G V F L + P + + VH G A L C V A
Sbjct: 1138 KADAGEYSCEAG---GQRV--SFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEV-A 1191
Query: 287 DPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
P EV+WY++ LS+S +V M +G L++ V D G YSC A + H+
Sbjct: 1192 QPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHI 1251
Score = 62.5 bits (145), Expect = 3e-09
Identities = 62/221 (28%), Positives = 91/221 (41%), Gaps = 29/221 (13%)
Query: 128 TRRITSEQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRH--VT 185
TRR+ +Q G DAG+Y C+ + Q+H E P +V A + H V
Sbjct: 1220 TRRLVVQQVGKA-------DAGEYSCEAGGQRVSFQLHITE---PKAVFAKEQLVHNEVR 1269
Query: 186 ARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRL-----GEGPQLQLSRLERHHGGVY 237
G +A L C A VTW++ SSS++ G QL + + + G Y
Sbjct: 1270 TEAGASATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEY 1328
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTV---LADPPAEVSW 294
C G + F L V P + + H A + T+ +A EV+W
Sbjct: 1329 TCEAG---GQRL--SFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTW 1383
Query: 295 YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
Y++ LS+S +V M A G L++ D G YSC A
Sbjct: 1384 YKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA 1424
Score = 59.7 bits (138), Expect = 2e-08
Identities = 55/198 (27%), Positives = 85/198 (42%), Gaps = 16/198 (8%)
Query: 148 AGDYVCQISDRVARDQVHTVEVLVPPSVRAS--PETRHVTARRGGAAVLECRAAGNPVPT 205
AG+Y C+ + +H E P +V A P +R V A G +A L C A
Sbjct: 1509 AGEYSCEAGSQRLSFHLHVAE---PKAVFAKEQPASREVQAEAGTSATLSCEVA-QAQTE 1564
Query: 206 VTWHR----LNDSSS----RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
VTW++ L+ SS +G +L + + G Y+C + + + +V
Sbjct: 1565 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKAGDQRLSFHLHVAEPKV 1624
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
++ E R V G A L C V A EV+WY++ LS+S +V + A G
Sbjct: 1625 VFAKEQPAHRE-VQAEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRR 1682
Query: 318 LLIADVQPEDFGNYSCVA 335
L++ + G YSC A
Sbjct: 1683 LVVQQAGQAEAGEYSCEA 1700
Score = 58.4 bits (135), Expect = 5e-08
Identities = 58/208 (27%), Positives = 80/208 (38%), Gaps = 20/208 (9%)
Query: 152 VCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRL 211
+C I R+A + V PP E TA G L CR G P P ++W++
Sbjct: 5999 ICGIQQRLA------LPVWRPPDFEE--ELADCTAELGETVKLACRVTGTPKPVISWYKD 6050
Query: 212 N-----DSSSRLGEGPQ----LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE 262
D L E P L L L G Y C + G T ++ V PP
Sbjct: 6051 GKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAG-NCSTLGKILVQVPPR 6109
Query: 263 ITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERV-TMS-ARGSNHTLLI 320
+ EG A+ CT+ P ++ WY++ L+ + T+S R L+I
Sbjct: 6110 FVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVI 6169
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEV 348
ED G Y C N LG AR E+
Sbjct: 6170 RAASKEDLGLYECELVNRLGSARASAEL 6197
Score = 57.6 bits (133), Expect = 9e-08
Identities = 64/216 (29%), Positives = 88/216 (40%), Gaps = 26/216 (12%)
Query: 146 QDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPET--RHVTARRGGAAVLECRAAGNP 202
QD G Y C RV D V + V P V A + R + A G +A L C A
Sbjct: 863 QDEGTYSC----RVGEDSVDFRLRVSEPKVVFAKEQLARRKLQAEAGASATLSCEVA-QA 917
Query: 203 VPTVTWHR----LNDSSSRLGEGP----QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
VTW++ L+ SS E +L + + + G Y+C G + F
Sbjct: 918 QTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAG---GQRL--SFH 972
Query: 255 LQVLYPPEI----TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
L V P + V S V G A L C V A EV WY++ LS+S +V +
Sbjct: 973 LDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEV-AQAQTEVMWYKDGKKLSSSLKVHVE 1031
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
A+G L++ D G+YSC A R H+
Sbjct: 1032 AKGCRRRLVVQQAGKTDAGDYSCEARGQRVSFRLHI 1067
Score = 56.0 bits (129), Expect = 3e-07
Identities = 52/197 (26%), Positives = 80/197 (40%), Gaps = 15/197 (7%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG+Y C+ D+ +H E V + P R V A G +A L C A V
Sbjct: 1600 DAGEYSCKAGDQRLSFHLHVAEPKVV-FAKEQPAHREVQAEAGASATLSCEVA-QAQTEV 1657
Query: 207 TWHR----LNDSSS----RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
TW++ L+ SS +G +L + + + G Y+C G + Q+ L
Sbjct: 1658 TWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSCEAG---GQQLSFRLQVAEL 1714
Query: 259 YPP--EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
P E R + E L T+ A V+W ++ + S+R +++G H
Sbjct: 1715 EPQISERPCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTH 1774
Query: 317 TLLIADVQPEDFGNYSC 333
TL + Q D YSC
Sbjct: 1775 TLTVHGAQVLDSAIYSC 1791
Score = 55.6 bits (128), Expect = 4e-07
Identities = 57/210 (27%), Positives = 82/210 (39%), Gaps = 18/210 (8%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D G+Y C R T+ V P V P + + A G A L+C + P TV
Sbjct: 3866 DTGEYSCVCGQE--RTSA-TLTVRAPQPVFREP-LQSLQAEEGSTATLQCELS-EPTATV 3920
Query: 207 TWHR----LNDSSSR----LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W + L + R G +L L L+R G Y CT + +T V
Sbjct: 3921 VWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTCTCGSQATSATLTVTAAPVR 3980
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
+ E+ + EG A L C L+ A V W + S L + M G+ L
Sbjct: 3981 FLRELQHQE----VDEGGTAHLCCE-LSRAGASVEWRKGSLQLFPCAKYQMVQDGAAAEL 4035
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEV 348
L+ V+ ED G+Y+C ++ A V V
Sbjct: 4036 LVRGVEQEDAGDYTCDTGHTQSMASLSVRV 4065
Score = 54.4 bits (125), Expect = 9e-07
Identities = 55/201 (27%), Positives = 84/201 (41%), Gaps = 13/201 (6%)
Query: 183 HVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVY----- 237
+V A GG A+ EC+ + V TW L+D E ++ H +
Sbjct: 4348 NVEALEGGEALFECQLSQPEVAAHTW-LLDDEPVHTSENAEVVFFENGLRHLLLLKNLRP 4406
Query: 238 --ACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVL-ADPPAEVSW 294
+C V G V + F + EI G +A CT+ A P E SW
Sbjct: 4407 QDSCRVTFLAGDMVTSAFLTVRGWRLEILEPLKNAAVRAGAQACFTCTLSEAVPVGEASW 4466
Query: 295 YQNSFPLSASERV-TMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
Y N + + T++A GS+H LL+ QP G + +++ AR + V G P
Sbjct: 4467 YINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACRDAVASAR--LTVLGLPD 4524
Query: 354 PARFTSPPLARAPHSYTLSFA 374
P + +AR+ H+ TLS+A
Sbjct: 4525 PPE-DAEVVARSSHTVTLSWA 4544
Score = 54.0 bits (124), Expect = 1e-06
Identities = 50/174 (28%), Positives = 73/174 (41%), Gaps = 14/174 (8%)
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHR----LNDSSSR-----LGEGPQLQLSRLERHHG 234
V A GG A EC + V V W++ L S R +G +L + + R
Sbjct: 807 VDAVAGGPAQFECETSEAHVH-VHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDE 865
Query: 235 GVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSW 294
G Y+C V + + +V++ E R + G A L C V A EV+W
Sbjct: 866 GTYSCRVGEDSVDFRLRVSEPKVVFAKEQLARRK-LQAEAGASATLSCEV-AQAQTEVTW 923
Query: 295 YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
Y++ LS+S +V M A G L++ D G YSC A R H++V
Sbjct: 924 YKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQ--RLSFHLDV 975
Score = 54.0 bits (124), Expect = 1e-06
Identities = 53/208 (25%), Positives = 84/208 (40%), Gaps = 12/208 (5%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D G+Y C+ + + E V + P R V A+ G + L C A V
Sbjct: 1416 DTGEYSCEAGGQRLSFSLDVAEPKVV-FAKEQPVHREVQAQAGASTTLSCEVA-QAQTEV 1473
Query: 207 TWHR----LNDSSS----RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W++ L+ SS +G +L + + + G Y+C + + + + +
Sbjct: 1474 MWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEAGSQRLSFHLHVAEPKAV 1533
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
+ E R V G A L C V A EV+WY++ LS+S +V M A G L
Sbjct: 1534 FAKEQPASRE-VQAEAGTSATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRL 1591
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHV 346
++ + D G YSC A + HV
Sbjct: 1592 VVQEAGQADAGEYSCKAGDQRLSFHLHV 1619
Score = 52.0 bits (119), Expect = 5e-06
Identities = 49/171 (28%), Positives = 67/171 (39%), Gaps = 18/171 (10%)
Query: 189 GGAAVLECRAAGNPVPTVTWHR-----LNDSSSRLG-EGPQLQLSRLERHHG--GVYACT 240
G A L C+ GNP P V+W + + RL +G +L+ L+ G G Y C
Sbjct: 24 GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCR 83
Query: 241 VDNGVGPPVVTEFQLQV-------LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS 293
N +G LQV P + + + EG A C V P VS
Sbjct: 84 ARNAIG-EAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVS 142
Query: 294 WYQNSFPLSASE--RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
W ++ L + RV + G L I +P D G Y A+N LG A
Sbjct: 143 WSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAA 193
Score = 51.2 bits (117), Expect = 8e-06
Identities = 53/211 (25%), Positives = 85/211 (40%), Gaps = 17/211 (8%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+DAG+YVC+ D Q+ V VP V+ V A GG A +C + + V
Sbjct: 1873 EDAGEYVCESRDDHTSAQL---TVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDV-A 1928
Query: 206 VTWHR----LNDSS----SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V W R L S S+ G L +S L G + + + V
Sbjct: 1929 VVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVREAPV 1988
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
L+ ++ E V E+ T P E+ W +N+ L+ + V + A G+ H
Sbjct: 1989 LFKKKL--EPQTVEERSSVTLEVELT---RPWPELRWTRNATALAPGKNVEIHAEGARHR 2043
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
L++ +V D G + C + +A+ VE+
Sbjct: 2044 LVLHNVGFADRGFFGCETPDDKTQAKLTVEM 2074
Score = 50.8 bits (116), Expect = 1e-05
Identities = 63/284 (22%), Positives = 111/284 (39%), Gaps = 28/284 (9%)
Query: 102 TIYENSETSVALAILGATGHTNVWETTRRITSE-------QHGNTNF--RMIF---QDAG 149
T+ E ++ + G VW+ ++ +E + NF +++F D G
Sbjct: 248 TVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRG 307
Query: 150 DYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWH 209
Y C S+ V + + V+ P+V + + R +A C P W
Sbjct: 308 LYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVP-QPSTEAAWF 366
Query: 210 RLND---SSSRLG---EGPQLQLS--RLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP 261
+ +S++ G EG + +L+ + VY C G V E +Q
Sbjct: 367 KEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEG--SRTVAELAVQGNLLR 424
Query: 262 EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIA 321
++ ++ V G+ + C LA P V W +N + A RV +SA G+ HTL I+
Sbjct: 425 KLP-RKTAVRVGD---TAMFCVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTIS 480
Query: 322 DVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARA 365
ED G + +A + + V +P P + P+ +A
Sbjct: 481 QCCLEDVGQVAFMAGDCQTSTQFCVSAPRKP-PLQPPVDPVVKA 523
Score = 50.0 bits (114), Expect = 2e-05
Identities = 52/195 (26%), Positives = 78/195 (40%), Gaps = 19/195 (9%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG+Y C + + TV L R + ++ AR G AVL+C + V
Sbjct: 3778 DAGEYSC-VCGQERTSATLTVRAL---PARFIEDVKNQEAREGATAVLQCELS--KAAPV 3831
Query: 207 TWH------RLNDSSSRLGEGP--QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W R D S +G +LQ+ L G Y+C +T Q +
Sbjct: 3832 EWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQPV 3891
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
+ + + EG A L C L++P A V W + L A+ R +G L
Sbjct: 3892 FREPLQS----LQAEEGSTATLQCE-LSEPTATVVWSKGGLQLQANGRREPRLQGCTAEL 3946
Query: 319 LIADVQPEDFGNYSC 333
++ D+Q ED G Y+C
Sbjct: 3947 VLQDLQREDTGEYTC 3961
Score = 47.6 bits (108), Expect = 1e-04
Identities = 50/199 (25%), Positives = 78/199 (39%), Gaps = 20/199 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+D G+Y C + T+ V P VR E +H GG A L C + +
Sbjct: 3954 EDTGEYTCTCGSQATSA---TLTVTAAP-VRFLRELQHQEVDEGGTAHLCCELS-RAGAS 4008
Query: 206 VTWHR--------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V W + + G +L + +E+ G Y C D G + + L V
Sbjct: 4009 VEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTC--DTGHTQSMAS---LSV 4063
Query: 258 LYP-PEITVERSWVHTGEGFRAELVCTVL-ADPPAEVSWYQNSFPLSASERVTMSARGSN 315
P P+ + G A L C + A+ A V W + L A + M ++G+
Sbjct: 4064 RVPRPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGAT 4123
Query: 316 HTLLIADVQPEDFGNYSCV 334
LLI ++ +D G Y+CV
Sbjct: 4124 RELLIHQLEAKDTGEYACV 4142
Score = 46.8 bits (106), Expect = 2e-04
Identities = 41/142 (28%), Positives = 59/142 (41%), Gaps = 9/142 (6%)
Query: 272 TGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNY 331
TG ++ ++ P V WY++ PLS SE+ MS G L I + P D G Y
Sbjct: 2479 TGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVY 2538
Query: 332 SCVADNSLGRARRHVEVSGRPGPARFTSP-PLARAPHSYTLSFAVDSYPPLDELRLLYRQ 390
C A G A EV+ T P A A SF+ + +E+
Sbjct: 2539 RCQA----GSAHSSTEVTVEAREVTVTGPLQDAEATEEGWASFSCELSHEDEEVEWSLNG 2594
Query: 391 LAI-NESFQQ---PGRWHDVVL 408
+ + N+SF + GR H +VL
Sbjct: 2595 MPLYNDSFHEISHKGRRHTLVL 2616
Score = 46.8 bits (106), Expect = 2e-04
Identities = 54/219 (24%), Positives = 88/219 (40%), Gaps = 24/219 (10%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG+Y+C + + T+ L R + ++ AR G AVL+C N V
Sbjct: 3514 DAGEYLC-VCGQERTSATLTIRAL---PARFIEDVKNQEAREGATAVLQCEL--NSAAPV 3567
Query: 207 TWHR----LND----SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W + L D S + G +LQ+ L G Y+C ++T L +
Sbjct: 3568 EWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRALPIK 3627
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
+ + E + EG A L C + P E W++ L +R ++ G+ L
Sbjct: 3628 FTEGLRNEEAT----EGATAVLRCELSKMAPVE--WWKGHETLRDGDRHSLRQDGARCEL 3681
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF 357
I + ED G Y C+ G+ R ++ R P++F
Sbjct: 3682 QIRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKF 3716
Score = 46.4 bits (105), Expect = 2e-04
Identities = 58/220 (26%), Positives = 82/220 (37%), Gaps = 23/220 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
QD+G Y C+ + V V P VR + + GGAA L C + P
Sbjct: 3160 QDSGRYKCEAGGACSSS---IVRVHARP-VRFQEALKDLEVLEGGAATLRCVLSSVAAP- 3214
Query: 206 VTWH------RLNDSSSRLGEGPQLQL--SRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V W R D S EG L+L L G Y+C+ + +T L
Sbjct: 3215 VKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSCSFGDQTTSATLTVTALPA 3274
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
+ ++ + + EG A L C + P E W + S L +R + G+
Sbjct: 3275 QFIGKLRNKEAT----EGATATLRCELSKAAPVE--WRKGSETLRDGDRYCLRQDGAMCE 3328
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF 357
L I + D YSCV G R ++ RP PA F
Sbjct: 3329 LQIRGLAMVDAAEYSCVC----GEERTSASLTIRPMPAHF 3364
Score = 46.0 bits (104), Expect = 3e-04
Identities = 44/172 (25%), Positives = 68/172 (39%), Gaps = 14/172 (8%)
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHR---LNDSSSR--LGEGPQ---- 223
P+ S TR T G A L C G P P W + L R + E Q
Sbjct: 236 PASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFV 295
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSW--VHTGEGFRAELV 281
L++ ++ G+Y CT N VG + L V+ P + ++ + E A +
Sbjct: 296 LKILFCKQSDRGLYTCTASNLVGQTYSS--VLVVVREPAVPFKKRLQDLEVREKESATFL 353
Query: 282 CTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
C V P E +W++ L AS + + G+ L + +V +D Y C
Sbjct: 354 CEV-PQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYIC 404
Score = 44.8 bits (101), Expect = 7e-04
Identities = 36/144 (25%), Positives = 59/144 (40%), Gaps = 8/144 (5%)
Query: 210 RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP----PEITV 265
R + + LG G +++L +E+ V C + PVV L L P
Sbjct: 5074 RFQEMFATLGIGVEIKL--VEQGPRRVEMC-ISKETPAPVVPPEPLPSLLTSDAAPVFLT 5130
Query: 266 ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA-RGSNHTLLIADVQ 324
E +G+ C V P V W+++ L + ++ + H L+I V
Sbjct: 5131 ELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVV 5190
Query: 325 PEDFGNYSCVADNSLGRARRHVEV 348
P D G Y C+A+NS+G + E+
Sbjct: 5191 PADMGVYRCLAENSMGVSSTKAEL 5214
Score = 44.4 bits (100), Expect = 0.001
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 261 PEITVERSWVHTGEGFR-AELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
P++ E + G R A+ V P + W+++ PL+AS + M+ + HTL
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLE 5319
Query: 320 IADVQPEDFGNYSCVADNSLGRA 342
I V ED G Y+ N++G A
Sbjct: 5320 IISVTREDSGQYAAYISNAMGAA 5342
Score = 44.0 bits (99), Expect = 0.001
Identities = 51/212 (24%), Positives = 81/212 (38%), Gaps = 19/212 (8%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+DAG+Y C++ + +H E + + E ++ G AV C+ +P T
Sbjct: 2891 KDAGEYTCEVEASKSTASLHVEE----KANCFTEELTNLQVEEKGTAVFTCKTE-HPAAT 2945
Query: 206 VTWHR----LNDSS----SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
VTW + L S S+ G +L +S LE+ Y C + + +V
Sbjct: 2946 VTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRV 3005
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR-GSNH 316
I + V EG A C + V W+ + PL A+E + A+ G H
Sbjct: 3006 ----HIIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYH 3061
Query: 317 TLLIADVQPEDFGN-YSCVADNSLGRARRHVE 347
L + + +D G Y D A R E
Sbjct: 3062 VLTLRQLALKDSGTIYFEAGDQRASAALRVTE 3093
Score = 43.6 bits (98), Expect = 0.002
Identities = 56/214 (26%), Positives = 82/214 (38%), Gaps = 20/214 (9%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGN 201
R++ DAG Y CQ + +V TVE V + + A G A C +
Sbjct: 2529 RLMPADAGVYRCQAGSAHSSTEV-TVEAR---EVTVTGPLQDAEATEEGWASFSCELSHE 2584
Query: 202 PVPTVTWHR-----LNDSS---SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
V W NDS S G L L ++R G+ + V T
Sbjct: 2585 D-EEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRAS-----SLKVSTSA 2638
Query: 254 QLQVLYPPEITVER-SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
+L+V P + ++ + E L C V +DP A V W ++ L S++
Sbjct: 2639 RLEVRVKPVVFLKALDDLSAEERGTLALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHT 2697
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
L++ DV PED G Y+C + RAR V
Sbjct: 2698 AGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRV 2731
Score = 41.9 bits (94), Expect = 0.005
Identities = 74/273 (27%), Positives = 101/273 (36%), Gaps = 36/273 (13%)
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLG-------EGP--QLQLSRLERHHG 234
V GG L C + V W R ++ R+G EGP L + L
Sbjct: 1818 VCGELGGTVTLACELSP-ACAEVVW-RCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDA 1875
Query: 235 GVYACTVDNGVGPPVVTEFQLQVLYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEV 292
G Y C + T QL V P + S V EG A C V A V
Sbjct: 1876 GEYVCESRDDH-----TSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDVAVV 1930
Query: 293 SWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRP 352
W+++ L SE+ +S G++H+L I+D+ ED G + A+ + A V R
Sbjct: 1931 -WFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRV----RE 1985
Query: 353 GPARF---TSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLA 409
P F P S TL V+ P ELR A+ PG+ +V +
Sbjct: 1986 APVLFKKKLEPQTVEERSSVTLE--VELTRPWPELRWTRNATAL-----APGK--NVEIH 2036
Query: 410 APAAKGSLT-HRVSHELRGLQPAAVYEAIVQAK 441
A A+ L H V RG + QAK
Sbjct: 2037 AEGARHRLVLHNVGFADRGFFGCETPDDKTQAK 2069
Score = 40.7 bits (91), Expect = 0.012
Identities = 49/206 (23%), Positives = 79/206 (38%), Gaps = 18/206 (8%)
Query: 136 HGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLE 195
H T ++ +D+G + D+ A + E PSV S E T G L
Sbjct: 3061 HVLTLRQLALKDSGTIYFEAGDQRASAALRVTE---KPSV-FSRELTDATITEGEDLTLV 3116
Query: 196 CRAAGNPVPTVTWHR----LNDSS----SRLGEGPQLQLSRLERHHGGVYACTVDNGVGP 247
C + +P V W + L S+ S G QL ++ G Y C
Sbjct: 3117 CETSTCDIP-VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSS 3175
Query: 248 PVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERV 307
+V V + + + EG A L C VL+ A V W + L ++
Sbjct: 3176 SIVRVHARPVRFQEALKD----LEVLEGGAATLRC-VLSSVAAPVKWCYGNNVLRPGDKY 3230
Query: 308 TMSARGSNHTLLIADVQPEDFGNYSC 333
++ G+ L++ +++P+D G YSC
Sbjct: 3231 SLRQEGAMLELVVRNLRPQDSGRYSC 3256
Score = 40.7 bits (91), Expect = 0.012
Identities = 54/220 (24%), Positives = 85/220 (38%), Gaps = 24/220 (10%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG+Y C + + TV+ L + + R+ A G A+L C + V V
Sbjct: 3426 DAGEYSCVCGEERTSATL-TVKAL---PAKFTEGLRNEEAVEGATAMLWCELS--KVAPV 3479
Query: 207 TWHR----LNDSSSRL----GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W + L D + G +LQ+ L G Y C +T L
Sbjct: 3480 EWRKGPENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATLTIRALPAR 3539
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
+ ++ + + EG A L C + + P E W + S L +R ++ G+ L
Sbjct: 3540 FIEDVKNQEA----REGATAVLQCELNSAAPVE--WRKGSETLRDGDRYSLRQDGTKCEL 3593
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFT 358
I + D G YSCV G+ R ++ R P +FT
Sbjct: 3594 QIRGLAMADTGEYSCVC----GQERTSAMLTVRALPIKFT 3629
Score = 40.3 bits (90), Expect = 0.015
Identities = 48/198 (24%), Positives = 76/198 (38%), Gaps = 16/198 (8%)
Query: 143 MIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAA-GN 201
++ +DAG+Y+C + + TV + + R+ A G A L C +
Sbjct: 3686 LVAEDAGEYLCMCG-KERTSAMLTVRAMPSKFIEG---LRNEEATEGDTATLWCELSKAA 3741
Query: 202 PVPTVTWH---RLNDSSSRLGEGP--QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
PV H R D S +G +LQ+ L G Y+C +T L
Sbjct: 3742 PVEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSCVCGQERTSATLTVRALP 3801
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
+ ++ + + EG A L C + P E W + S L +R ++ G+
Sbjct: 3802 ARFIEDVKNQEA----REGATAVLQCELSKAAPVE--WRKGSETLRGGDRYSLRQDGTRC 3855
Query: 317 TLLIADVQPEDFGNYSCV 334
L I + D G YSCV
Sbjct: 3856 ELQIHGLSVADTGEYSCV 3873
Score = 39.5 bits (88), Expect = 0.027
Identities = 29/117 (24%), Positives = 45/117 (38%), Gaps = 18/117 (15%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRH-------VTARRGGAAVLECRAA 199
D+G YVC+ + + + V + V + + H + R G A CR
Sbjct: 76 DSGQYVCRARNAIG-EAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVG 134
Query: 200 GNPVPTVTW----HRLNDSS------SRLGEGPQLQLSRLERHHGGVYACTVDNGVG 246
G+P P V+W RL + LGE L++ GG Y +N +G
Sbjct: 135 GSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLG 191
Score = 39.5 bits (88), Expect = 0.027
Identities = 39/128 (30%), Positives = 51/128 (39%), Gaps = 9/128 (7%)
Query: 219 GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWV--HTGEGF 276
G +L + +LE G YAC V G T L+V PE+T+ R V
Sbjct: 4121 GATRELLIHQLEAKDTGEYAC-VTGGQK----TAASLRVT-EPEVTIVRGLVDAEVTADE 4174
Query: 277 RAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR-GSNHTLLIADVQPEDFGNYSCVA 335
E C V V W PL ++E ++ R G HTL + V PED G S
Sbjct: 4175 DVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHL 4234
Query: 336 DNSLGRAR 343
N A+
Sbjct: 4235 GNHASSAQ 4242
Score = 38.3 bits (85), Expect = 0.062
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
Query: 285 LADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
L+D A V+W ++ LS + + A LL+ DV +D G Y CV+ GR
Sbjct: 730 LSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRG--GRIAY 787
Query: 345 HVEVSG 350
+ V G
Sbjct: 788 QLSVQG 793
Score = 36.7 bits (81), Expect = 0.19
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 3/83 (3%)
Query: 265 VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQ 324
+E WV GE EL C L+ V W ++ + S++ + G+ L+I
Sbjct: 2833 LEDQWVAPGED--VELRCE-LSRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGAS 2889
Query: 325 PEDFGNYSCVADNSLGRARRHVE 347
+D G Y+C + S A HVE
Sbjct: 2890 LKDAGEYTCEVEASKSTASLHVE 2912
Score = 36.3 bits (80), Expect = 0.25
Identities = 55/218 (25%), Positives = 80/218 (36%), Gaps = 26/218 (11%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+ Y C I +R Q+ ++ V + V + G +A CR + V
Sbjct: 2981 DSDTYTCDIGQAQSRAQL----LVQGRRVHIIEDLEDVDVQEGSSATFRCRISPANYEPV 3036
Query: 207 TW---------HRLNDSSSRLGEGPQLQLSRLE-RHHGGVYACTVDNGVGPPV-VTEFQL 255
W + LN+ ++ G L L +L + G +Y D + VTE
Sbjct: 3037 HWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSGTIYFEAGDQRASAALRVTE--- 3093
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVC-TVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
P + E + EG LVC T D P V W ++ L S R +S G
Sbjct: 3094 ---KPSVFSRELTDATITEGEDLTLVCETSTCDIP--VCWTKDGKTLRGSARCQLSHEGH 3148
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRP 352
LLI +D G Y C A + + V V RP
Sbjct: 3149 RAQLLITGATLQDSGRYKCEAGGACSSS--IVRVHARP 3184
Score = 35.9 bits (79), Expect = 0.33
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
E R L C V + A+V W++ S L + + + G L+I+DV ED Y+C
Sbjct: 2303 EKHRGVLECQV-SRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTC 2361
Query: 334 VADNSLGRARRHVE 347
A + A+ VE
Sbjct: 2362 DAGDVKTSAQFFVE 2375
Score = 35.5 bits (78), Expect = 0.44
Identities = 56/214 (26%), Positives = 90/214 (42%), Gaps = 18/214 (8%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
F D G + C+ D + ++ TVE+ VR + V AR G A +E + + V
Sbjct: 2051 FADRGFFGCETPDDKTQAKL-TVEMR---QVRLVRGLQAVEAREQGTATMEVQLSHADVD 2106
Query: 205 TVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACT--VDNGV----GPPVVTEFQLQVL 258
+W R R +GP L+ H + D+G+ V T +L V
Sbjct: 2107 G-SWTR---DGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAEGVHTSARLVVT 2162
Query: 259 -YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
P + V T E + L C L+ P +V W ++ L A + + ++A+G+ +
Sbjct: 2163 ELPVSFSRPLQDVVTTEKEKVTLECE-LSRPNVDVRWLKDGVELRAGKTMAIAAQGACRS 2221
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR 351
L I + D G Y C A ++ A V+V GR
Sbjct: 2222 LTIYRCEFADQGVYVCDAHDAQSSA--SVKVQGR 2253
Score = 35.1 bits (77), Expect = 0.58
Identities = 16/47 (34%), Positives = 28/47 (59%), Gaps = 2/47 (4%)
Query: 308 TMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA--RRHVEVSGRP 352
T+++ H+L++ DV + G Y+C+A N+ G+A + VSG P
Sbjct: 5424 TVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLP 5470
Score = 34.3 bits (75), Expect = 1.0
Identities = 47/198 (23%), Positives = 74/198 (37%), Gaps = 20/198 (10%)
Query: 146 QDAGDYVC-------QISDRVARDQVHTVEVLVPPSVRASPETRH-VTARRGGAAVLECR 197
+D G+Y C S RV +V V LV V A + R GA ++
Sbjct: 4134 KDTGEYACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQWC 4193
Query: 198 AAGNPVPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
G P+ + + + + + R G L+L + G + + N +T
Sbjct: 4194 LQGLPLQS---NEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLT------ 4244
Query: 258 LYPPEITVERSW--VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA-RGS 314
+ PE+T+ V EG A C + E W PL A+E ++ +G+
Sbjct: 4245 VRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGT 4304
Query: 315 NHTLLIADVQPEDFGNYS 332
H L + V ED G S
Sbjct: 4305 LHLLTLHKVTLEDAGTVS 4322
Score = 33.9 bits (74), Expect = 1.3
Identities = 52/221 (23%), Positives = 80/221 (36%), Gaps = 24/221 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
QD+G Y C D+ T+ V P+ + + R+ A G A L C +
Sbjct: 3249 QDSGRYSCSFGDQTTSA---TLTVTALPA-QFIGKLRNKEATEGATATLRCELS--KAAP 3302
Query: 206 VTWHR----LNDSSSRL----GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V W + L D G +LQ+ L Y+C +T +
Sbjct: 3303 VEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLTIRPMPA 3362
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
+ + + S EG A L C + P E W + L +R ++ G+
Sbjct: 3363 HFIGRLRHQESI----EGATATLRCELSKAAPVE--WRKGRESLRDGDRHSLRQDGAVCE 3416
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFT 358
L I + D G YSCV G R ++ + PA+FT
Sbjct: 3417 LQICGLAVADAGEYSCVC----GEERTSATLTVKALPAKFT 3453
Score = 33.1 bits (72), Expect = 2.3
Identities = 27/93 (29%), Positives = 34/93 (36%), Gaps = 16/93 (17%)
Query: 168 EVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGP----- 222
E LVPP + + V ++G + + G PVPTV W R L GP
Sbjct: 5366 EQLVPPRMLERFTPKKV--KKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGY 5423
Query: 223 ---------QLQLSRLERHHGGVYACTVDNGVG 246
L L + R H G Y C N G
Sbjct: 5424 TVASSAQQHSLVLLDVGRQHQGTYTCIASNAAG 5456
>AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 74.1 bits (174), Expect = 1e-12
Identities = 70/240 (29%), Positives = 103/240 (42%), Gaps = 31/240 (12%)
Query: 121 HTNVWETTRRITSEQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPE 180
H RR+ +Q G T DAGDY C+ + ++H E P + A +
Sbjct: 1029 HVEAKGCRRRLVVQQAGKT-------DAGDYSCEARGQRVSFRLHITE---PKMMFAKEQ 1078
Query: 181 TRH--VTARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRLG---EG--PQLQLSRLE 230
+ H V A G +A+L C A VTW++ SSS++G +G +L L +
Sbjct: 1079 SVHNEVQAEAGASAMLSCEVA-QAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAG 1137
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTG----EGFRAELVCTVLA 286
+ G Y+C G V F L + P + + VH G A L C V A
Sbjct: 1138 KADAGEYSCEAG---GQRV--SFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEV-A 1191
Query: 287 DPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
P EV+WY++ LS+S +V M +G L++ V D G YSC A + H+
Sbjct: 1192 QPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHI 1251
Score = 62.5 bits (145), Expect = 3e-09
Identities = 62/221 (28%), Positives = 91/221 (41%), Gaps = 29/221 (13%)
Query: 128 TRRITSEQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRH--VT 185
TRR+ +Q G DAG+Y C+ + Q+H E P +V A + H V
Sbjct: 1220 TRRLVVQQVGKA-------DAGEYSCEAGGQRVSFQLHITE---PKAVFAKEQLVHNEVR 1269
Query: 186 ARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRL-----GEGPQLQLSRLERHHGGVY 237
G +A L C A VTW++ SSS++ G QL + + + G Y
Sbjct: 1270 TEAGASATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEY 1328
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTV---LADPPAEVSW 294
C G + F L V P + + H A + T+ +A EV+W
Sbjct: 1329 TCEAG---GQRL--SFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTW 1383
Query: 295 YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
Y++ LS+S +V M A G L++ D G YSC A
Sbjct: 1384 YKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA 1424
Score = 59.7 bits (138), Expect = 2e-08
Identities = 55/198 (27%), Positives = 85/198 (42%), Gaps = 16/198 (8%)
Query: 148 AGDYVCQISDRVARDQVHTVEVLVPPSVRAS--PETRHVTARRGGAAVLECRAAGNPVPT 205
AG+Y C+ + +H E P +V A P +R V A G +A L C A
Sbjct: 1509 AGEYSCEAGSQRLSFHLHVAE---PKAVFAKEQPASREVQAEAGTSATLSCEVA-QAQTE 1564
Query: 206 VTWHR----LNDSSS----RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
VTW++ L+ SS +G +L + + G Y+C + + + +V
Sbjct: 1565 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKAGDQRLSFHLHVAEPKV 1624
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
++ E R V G A L C V A EV+WY++ LS+S +V + A G
Sbjct: 1625 VFAKEQPAHRE-VQAEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRR 1682
Query: 318 LLIADVQPEDFGNYSCVA 335
L++ + G YSC A
Sbjct: 1683 LVVQQAGQAEAGEYSCEA 1700
Score = 58.4 bits (135), Expect = 5e-08
Identities = 58/208 (27%), Positives = 80/208 (38%), Gaps = 20/208 (9%)
Query: 152 VCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRL 211
+C I R+A + V PP E TA G L CR G P P ++W++
Sbjct: 5999 ICGIQQRLA------LPVWRPPDFEE--ELADCTAELGETVKLACRVTGTPKPVISWYKD 6050
Query: 212 N-----DSSSRLGEGPQ----LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE 262
D L E P L L L G Y C + G T ++ V PP
Sbjct: 6051 GKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAG-NCSTLGKILVQVPPR 6109
Query: 263 ITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERV-TMS-ARGSNHTLLI 320
+ EG A+ CT+ P ++ WY++ L+ + T+S R L+I
Sbjct: 6110 FVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVI 6169
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEV 348
ED G Y C N LG AR E+
Sbjct: 6170 RAASKEDLGLYECELVNRLGSARASAEL 6197
Score = 57.6 bits (133), Expect = 9e-08
Identities = 64/216 (29%), Positives = 88/216 (40%), Gaps = 26/216 (12%)
Query: 146 QDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPET--RHVTARRGGAAVLECRAAGNP 202
QD G Y C RV D V + V P V A + R + A G +A L C A
Sbjct: 863 QDEGTYSC----RVGEDSVDFRLRVSEPKVVFAKEQLARRKLQAEAGASATLSCEVA-QA 917
Query: 203 VPTVTWHR----LNDSSSRLGEGP----QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
VTW++ L+ SS E +L + + + G Y+C G + F
Sbjct: 918 QTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAG---GQRL--SFH 972
Query: 255 LQVLYPPEI----TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
L V P + V S V G A L C V A EV WY++ LS+S +V +
Sbjct: 973 LDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEV-AQAQTEVMWYKDGKKLSSSLKVHVE 1031
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
A+G L++ D G+YSC A R H+
Sbjct: 1032 AKGCRRRLVVQQAGKTDAGDYSCEARGQRVSFRLHI 1067
Score = 56.0 bits (129), Expect = 3e-07
Identities = 52/197 (26%), Positives = 80/197 (40%), Gaps = 15/197 (7%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG+Y C+ D+ +H E V + P R V A G +A L C A V
Sbjct: 1600 DAGEYSCKAGDQRLSFHLHVAEPKVV-FAKEQPAHREVQAEAGASATLSCEVA-QAQTEV 1657
Query: 207 TWHR----LNDSSS----RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
TW++ L+ SS +G +L + + + G Y+C G + Q+ L
Sbjct: 1658 TWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSCEAG---GQQLSFRLQVAEL 1714
Query: 259 YPP--EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
P E R + E L T+ A V+W ++ + S+R +++G H
Sbjct: 1715 EPQISERPCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTH 1774
Query: 317 TLLIADVQPEDFGNYSC 333
TL + Q D YSC
Sbjct: 1775 TLTVHGAQVLDSAIYSC 1791
Score = 55.6 bits (128), Expect = 4e-07
Identities = 57/210 (27%), Positives = 82/210 (39%), Gaps = 18/210 (8%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D G+Y C R T+ V P V P + + A G A L+C + P TV
Sbjct: 3866 DTGEYSCVCGQE--RTSA-TLTVRAPQPVFREP-LQSLQAEEGSTATLQCELS-EPTATV 3920
Query: 207 TWHR----LNDSSSR----LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W + L + R G +L L L+R G Y CT + +T V
Sbjct: 3921 VWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTCTCGSQATSATLTVTAAPVR 3980
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
+ E+ + EG A L C L+ A V W + S L + M G+ L
Sbjct: 3981 FLRELQHQE----VDEGGTAHLCCE-LSRAGASVEWRKGSLQLFPCAKYQMVQDGAAAEL 4035
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEV 348
L+ V+ ED G+Y+C ++ A V V
Sbjct: 4036 LVRGVEQEDAGDYTCDTGHTQSMASLSVRV 4065
Score = 54.4 bits (125), Expect = 9e-07
Identities = 55/201 (27%), Positives = 84/201 (41%), Gaps = 13/201 (6%)
Query: 183 HVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVY----- 237
+V A GG A+ EC+ + V TW L+D E ++ H +
Sbjct: 4348 NVEALEGGEALFECQLSQPEVAAHTW-LLDDEPVHTSENAEVVFFENGLRHLLLLKNLRP 4406
Query: 238 --ACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVL-ADPPAEVSW 294
+C V G V + F + EI G +A CT+ A P E SW
Sbjct: 4407 QDSCRVTFLAGDMVTSAFLTVRGWRLEILEPLKNAAVRAGAQACFTCTLSEAVPVGEASW 4466
Query: 295 YQNSFPLSASERV-TMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
Y N + + T++A GS+H LL+ QP G + +++ AR + V G P
Sbjct: 4467 YINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACRDAVASAR--LTVLGLPD 4524
Query: 354 PARFTSPPLARAPHSYTLSFA 374
P + +AR+ H+ TLS+A
Sbjct: 4525 PPE-DAEVVARSSHTVTLSWA 4544
Score = 54.0 bits (124), Expect = 1e-06
Identities = 50/174 (28%), Positives = 73/174 (41%), Gaps = 14/174 (8%)
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHR----LNDSSSR-----LGEGPQLQLSRLERHHG 234
V A GG A EC + V V W++ L S R +G +L + + R
Sbjct: 807 VDAVAGGPAQFECETSEAHVH-VHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDE 865
Query: 235 GVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSW 294
G Y+C V + + +V++ E R + G A L C V A EV+W
Sbjct: 866 GTYSCRVGEDSVDFRLRVSEPKVVFAKEQLARRK-LQAEAGASATLSCEV-AQAQTEVTW 923
Query: 295 YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
Y++ LS+S +V M A G L++ D G YSC A R H++V
Sbjct: 924 YKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQ--RLSFHLDV 975
Score = 54.0 bits (124), Expect = 1e-06
Identities = 53/208 (25%), Positives = 84/208 (40%), Gaps = 12/208 (5%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D G+Y C+ + + E V + P R V A+ G + L C A V
Sbjct: 1416 DTGEYSCEAGGQRLSFSLDVAEPKVV-FAKEQPVHREVQAQAGASTTLSCEVA-QAQTEV 1473
Query: 207 TWHR----LNDSSS----RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W++ L+ SS +G +L + + + G Y+C + + + + +
Sbjct: 1474 MWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEAGSQRLSFHLHVAEPKAV 1533
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
+ E R V G A L C V A EV+WY++ LS+S +V M A G L
Sbjct: 1534 FAKEQPASRE-VQAEAGTSATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRL 1591
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHV 346
++ + D G YSC A + HV
Sbjct: 1592 VVQEAGQADAGEYSCKAGDQRLSFHLHV 1619
Score = 52.0 bits (119), Expect = 5e-06
Identities = 49/171 (28%), Positives = 67/171 (39%), Gaps = 18/171 (10%)
Query: 189 GGAAVLECRAAGNPVPTVTWHR-----LNDSSSRLG-EGPQLQLSRLERHHG--GVYACT 240
G A L C+ GNP P V+W + + RL +G +L+ L+ G G Y C
Sbjct: 24 GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCR 83
Query: 241 VDNGVGPPVVTEFQLQV-------LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS 293
N +G LQV P + + + EG A C V P VS
Sbjct: 84 ARNAIG-EAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVS 142
Query: 294 WYQNSFPLSASE--RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
W ++ L + RV + G L I +P D G Y A+N LG A
Sbjct: 143 WSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAA 193
Score = 51.2 bits (117), Expect = 8e-06
Identities = 53/211 (25%), Positives = 85/211 (40%), Gaps = 17/211 (8%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+DAG+YVC+ D Q+ V VP V+ V A GG A +C + + V
Sbjct: 1873 EDAGEYVCESRDDHTSAQL---TVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDV-A 1928
Query: 206 VTWHR----LNDSS----SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V W R L S S+ G L +S L G + + + V
Sbjct: 1929 VVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVREAPV 1988
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
L+ ++ E V E+ T P E+ W +N+ L+ + V + A G+ H
Sbjct: 1989 LFKKKL--EPQTVEERSSVTLEVELT---RPWPELRWTRNATALAPGKNVEIHAEGARHR 2043
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
L++ +V D G + C + +A+ VE+
Sbjct: 2044 LVLHNVGFADRGFFGCETPDDKTQAKLTVEM 2074
Score = 50.8 bits (116), Expect = 1e-05
Identities = 63/284 (22%), Positives = 111/284 (39%), Gaps = 28/284 (9%)
Query: 102 TIYENSETSVALAILGATGHTNVWETTRRITSE-------QHGNTNF--RMIF---QDAG 149
T+ E ++ + G VW+ ++ +E + NF +++F D G
Sbjct: 248 TVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRG 307
Query: 150 DYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWH 209
Y C S+ V + + V+ P+V + + R +A C P W
Sbjct: 308 LYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVP-QPSTEAAWF 366
Query: 210 RLND---SSSRLG---EGPQLQLS--RLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP 261
+ +S++ G EG + +L+ + VY C G V E +Q
Sbjct: 367 KEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEG--SRTVAELAVQGNLLR 424
Query: 262 EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIA 321
++ ++ V G+ + C LA P V W +N + A RV +SA G+ HTL I+
Sbjct: 425 KLP-RKTAVRVGD---TAMFCVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTIS 480
Query: 322 DVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARA 365
ED G + +A + + V +P P + P+ +A
Sbjct: 481 QCCLEDVGQVAFMAGDCQTSTQFCVSAPRKP-PLQPPVDPVVKA 523
Score = 50.0 bits (114), Expect = 2e-05
Identities = 52/195 (26%), Positives = 78/195 (40%), Gaps = 19/195 (9%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG+Y C + + TV L R + ++ AR G AVL+C + V
Sbjct: 3778 DAGEYSC-VCGQERTSATLTVRAL---PARFIEDVKNQEAREGATAVLQCELS--KAAPV 3831
Query: 207 TWH------RLNDSSSRLGEGP--QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W R D S +G +LQ+ L G Y+C +T Q +
Sbjct: 3832 EWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQPV 3891
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
+ + + EG A L C L++P A V W + L A+ R +G L
Sbjct: 3892 FREPLQS----LQAEEGSTATLQCE-LSEPTATVVWSKGGLQLQANGRREPRLQGCTAEL 3946
Query: 319 LIADVQPEDFGNYSC 333
++ D+Q ED G Y+C
Sbjct: 3947 VLQDLQREDTGEYTC 3961
Score = 47.6 bits (108), Expect = 1e-04
Identities = 50/199 (25%), Positives = 78/199 (39%), Gaps = 20/199 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+D G+Y C + T+ V P VR E +H GG A L C + +
Sbjct: 3954 EDTGEYTCTCGSQATSA---TLTVTAAP-VRFLRELQHQEVDEGGTAHLCCELS-RAGAS 4008
Query: 206 VTWHR--------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V W + + G +L + +E+ G Y C D G + + L V
Sbjct: 4009 VEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTC--DTGHTQSMAS---LSV 4063
Query: 258 LYP-PEITVERSWVHTGEGFRAELVCTVL-ADPPAEVSWYQNSFPLSASERVTMSARGSN 315
P P+ + G A L C + A+ A V W + L A + M ++G+
Sbjct: 4064 RVPRPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGAT 4123
Query: 316 HTLLIADVQPEDFGNYSCV 334
LLI ++ +D G Y+CV
Sbjct: 4124 RELLIHQLEAKDTGEYACV 4142
Score = 46.8 bits (106), Expect = 2e-04
Identities = 41/142 (28%), Positives = 59/142 (41%), Gaps = 9/142 (6%)
Query: 272 TGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNY 331
TG ++ ++ P V WY++ PLS SE+ MS G L I + P D G Y
Sbjct: 2479 TGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVY 2538
Query: 332 SCVADNSLGRARRHVEVSGRPGPARFTSP-PLARAPHSYTLSFAVDSYPPLDELRLLYRQ 390
C A G A EV+ T P A A SF+ + +E+
Sbjct: 2539 RCQA----GSAHSSTEVTVEAREVTVTGPLQDAEATEEGWASFSCELSHEDEEVEWSLNG 2594
Query: 391 LAI-NESFQQ---PGRWHDVVL 408
+ + N+SF + GR H +VL
Sbjct: 2595 MPLYNDSFHEISHKGRRHTLVL 2616
Score = 46.8 bits (106), Expect = 2e-04
Identities = 54/219 (24%), Positives = 88/219 (40%), Gaps = 24/219 (10%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG+Y+C + + T+ L R + ++ AR G AVL+C N V
Sbjct: 3514 DAGEYLC-VCGQERTSATLTIRAL---PARFIEDVKNQEAREGATAVLQCEL--NSAAPV 3567
Query: 207 TWHR----LND----SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W + L D S + G +LQ+ L G Y+C ++T L +
Sbjct: 3568 EWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRALPIK 3627
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
+ + E + EG A L C + P E W++ L +R ++ G+ L
Sbjct: 3628 FTEGLRNEEAT----EGATAVLRCELSKMAPVE--WWKGHETLRDGDRHSLRQDGARCEL 3681
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF 357
I + ED G Y C+ G+ R ++ R P++F
Sbjct: 3682 QIRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKF 3716
Score = 46.4 bits (105), Expect = 2e-04
Identities = 58/220 (26%), Positives = 82/220 (37%), Gaps = 23/220 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
QD+G Y C+ + V V P VR + + GGAA L C + P
Sbjct: 3160 QDSGRYKCEAGGACSSS---IVRVHARP-VRFQEALKDLEVLEGGAATLRCVLSSVAAP- 3214
Query: 206 VTWH------RLNDSSSRLGEGPQLQL--SRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V W R D S EG L+L L G Y+C+ + +T L
Sbjct: 3215 VKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSCSFGDQTTSATLTVTALPA 3274
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
+ ++ + + EG A L C + P E W + S L +R + G+
Sbjct: 3275 QFIGKLRNKEAT----EGATATLRCELSKAAPVE--WRKGSETLRDGDRYCLRQDGAMCE 3328
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF 357
L I + D YSCV G R ++ RP PA F
Sbjct: 3329 LQIRGLAMVDAAEYSCVC----GEERTSASLTIRPMPAHF 3364
Score = 46.0 bits (104), Expect = 3e-04
Identities = 44/172 (25%), Positives = 68/172 (39%), Gaps = 14/172 (8%)
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHR---LNDSSSR--LGEGPQ---- 223
P+ S TR T G A L C G P P W + L R + E Q
Sbjct: 236 PASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFV 295
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSW--VHTGEGFRAELV 281
L++ ++ G+Y CT N VG + L V+ P + ++ + E A +
Sbjct: 296 LKILFCKQSDRGLYTCTASNLVGQTYSS--VLVVVREPAVPFKKRLQDLEVREKESATFL 353
Query: 282 CTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
C V P E +W++ L AS + + G+ L + +V +D Y C
Sbjct: 354 CEV-PQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYIC 404
Score = 44.8 bits (101), Expect = 7e-04
Identities = 36/144 (25%), Positives = 59/144 (40%), Gaps = 8/144 (5%)
Query: 210 RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP----PEITV 265
R + + LG G +++L +E+ V C + PVV L L P
Sbjct: 5074 RFQEMFATLGIGVEIKL--VEQGPRRVEMC-ISKETPAPVVPPEPLPSLLTSDAAPVFLT 5130
Query: 266 ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA-RGSNHTLLIADVQ 324
E +G+ C V P V W+++ L + ++ + H L+I V
Sbjct: 5131 ELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVV 5190
Query: 325 PEDFGNYSCVADNSLGRARRHVEV 348
P D G Y C+A+NS+G + E+
Sbjct: 5191 PADMGVYRCLAENSMGVSSTKAEL 5214
Score = 44.4 bits (100), Expect = 0.001
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 261 PEITVERSWVHTGEGFR-AELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
P++ E + G R A+ V P + W+++ PL+AS + M+ + HTL
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLE 5319
Query: 320 IADVQPEDFGNYSCVADNSLGRA 342
I V ED G Y+ N++G A
Sbjct: 5320 IISVTREDSGQYAAYISNAMGAA 5342
Score = 44.0 bits (99), Expect = 0.001
Identities = 51/212 (24%), Positives = 81/212 (38%), Gaps = 19/212 (8%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+DAG+Y C++ + +H E + + E ++ G AV C+ +P T
Sbjct: 2891 KDAGEYTCEVEASKSTASLHVEE----KANCFTEELTNLQVEEKGTAVFTCKTE-HPAAT 2945
Query: 206 VTWHR----LNDSS----SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
VTW + L S S+ G +L +S LE+ Y C + + +V
Sbjct: 2946 VTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRV 3005
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR-GSNH 316
I + V EG A C + V W+ + PL A+E + A+ G H
Sbjct: 3006 ----HIIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYH 3061
Query: 317 TLLIADVQPEDFGN-YSCVADNSLGRARRHVE 347
L + + +D G Y D A R E
Sbjct: 3062 VLTLRQLALKDSGTIYFEAGDQRASAALRVTE 3093
Score = 43.6 bits (98), Expect = 0.002
Identities = 56/214 (26%), Positives = 82/214 (38%), Gaps = 20/214 (9%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGN 201
R++ DAG Y CQ + +V TVE V + + A G A C +
Sbjct: 2529 RLMPADAGVYRCQAGSAHSSTEV-TVEAR---EVTVTGPLQDAEATEEGWASFSCELSHE 2584
Query: 202 PVPTVTWHR-----LNDSS---SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
V W NDS S G L L ++R G+ + V T
Sbjct: 2585 D-EEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRAS-----SLKVSTSA 2638
Query: 254 QLQVLYPPEITVER-SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
+L+V P + ++ + E L C V +DP A V W ++ L S++
Sbjct: 2639 RLEVRVKPVVFLKALDDLSAEERGTLALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHT 2697
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
L++ DV PED G Y+C + RAR V
Sbjct: 2698 AGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRV 2731
Score = 41.9 bits (94), Expect = 0.005
Identities = 74/273 (27%), Positives = 101/273 (36%), Gaps = 36/273 (13%)
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLG-------EGP--QLQLSRLERHHG 234
V GG L C + V W R ++ R+G EGP L + L
Sbjct: 1818 VCGELGGTVTLACELSP-ACAEVVW-RCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDA 1875
Query: 235 GVYACTVDNGVGPPVVTEFQLQVLYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEV 292
G Y C + T QL V P + S V EG A C V A V
Sbjct: 1876 GEYVCESRDDH-----TSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDVAVV 1930
Query: 293 SWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRP 352
W+++ L SE+ +S G++H+L I+D+ ED G + A+ + A V R
Sbjct: 1931 -WFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRV----RE 1985
Query: 353 GPARF---TSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLA 409
P F P S TL V+ P ELR A+ PG+ +V +
Sbjct: 1986 APVLFKKKLEPQTVEERSSVTLE--VELTRPWPELRWTRNATAL-----APGK--NVEIH 2036
Query: 410 APAAKGSLT-HRVSHELRGLQPAAVYEAIVQAK 441
A A+ L H V RG + QAK
Sbjct: 2037 AEGARHRLVLHNVGFADRGFFGCETPDDKTQAK 2069
Score = 40.7 bits (91), Expect = 0.012
Identities = 49/206 (23%), Positives = 79/206 (38%), Gaps = 18/206 (8%)
Query: 136 HGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLE 195
H T ++ +D+G + D+ A + E PSV S E T G L
Sbjct: 3061 HVLTLRQLALKDSGTIYFEAGDQRASAALRVTE---KPSV-FSRELTDATITEGEDLTLV 3116
Query: 196 CRAAGNPVPTVTWHR----LNDSS----SRLGEGPQLQLSRLERHHGGVYACTVDNGVGP 247
C + +P V W + L S+ S G QL ++ G Y C
Sbjct: 3117 CETSTCDIP-VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSS 3175
Query: 248 PVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERV 307
+V V + + + EG A L C VL+ A V W + L ++
Sbjct: 3176 SIVRVHARPVRFQEALKD----LEVLEGGAATLRC-VLSSVAAPVKWCYGNNVLRPGDKY 3230
Query: 308 TMSARGSNHTLLIADVQPEDFGNYSC 333
++ G+ L++ +++P+D G YSC
Sbjct: 3231 SLRQEGAMLELVVRNLRPQDSGRYSC 3256
Score = 40.7 bits (91), Expect = 0.012
Identities = 54/220 (24%), Positives = 85/220 (38%), Gaps = 24/220 (10%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG+Y C + + TV+ L + + R+ A G A+L C + V V
Sbjct: 3426 DAGEYSCVCGEERTSATL-TVKAL---PAKFTEGLRNEEAVEGATAMLWCELS--KVAPV 3479
Query: 207 TWHR----LNDSSSRL----GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W + L D + G +LQ+ L G Y C +T L
Sbjct: 3480 EWRKGPENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATLTIRALPAR 3539
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
+ ++ + + EG A L C + + P E W + S L +R ++ G+ L
Sbjct: 3540 FIEDVKNQEA----REGATAVLQCELNSAAPVE--WRKGSETLRDGDRYSLRQDGTKCEL 3593
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFT 358
I + D G YSCV G+ R ++ R P +FT
Sbjct: 3594 QIRGLAMADTGEYSCVC----GQERTSAMLTVRALPIKFT 3629
Score = 40.3 bits (90), Expect = 0.015
Identities = 48/198 (24%), Positives = 76/198 (38%), Gaps = 16/198 (8%)
Query: 143 MIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAA-GN 201
++ +DAG+Y+C + + TV + + R+ A G A L C +
Sbjct: 3686 LVAEDAGEYLCMCG-KERTSAMLTVRAMPSKFIEG---LRNEEATEGDTATLWCELSKAA 3741
Query: 202 PVPTVTWH---RLNDSSSRLGEGP--QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
PV H R D S +G +LQ+ L G Y+C +T L
Sbjct: 3742 PVEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSCVCGQERTSATLTVRALP 3801
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
+ ++ + + EG A L C + P E W + S L +R ++ G+
Sbjct: 3802 ARFIEDVKNQEA----REGATAVLQCELSKAAPVE--WRKGSETLRGGDRYSLRQDGTRC 3855
Query: 317 TLLIADVQPEDFGNYSCV 334
L I + D G YSCV
Sbjct: 3856 ELQIHGLSVADTGEYSCV 3873
Score = 39.5 bits (88), Expect = 0.027
Identities = 29/117 (24%), Positives = 45/117 (38%), Gaps = 18/117 (15%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRH-------VTARRGGAAVLECRAA 199
D+G YVC+ + + + V + V + + H + R G A CR
Sbjct: 76 DSGQYVCRARNAIG-EAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVG 134
Query: 200 GNPVPTVTW----HRLNDSS------SRLGEGPQLQLSRLERHHGGVYACTVDNGVG 246
G+P P V+W RL + LGE L++ GG Y +N +G
Sbjct: 135 GSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLG 191
Score = 39.5 bits (88), Expect = 0.027
Identities = 39/128 (30%), Positives = 51/128 (39%), Gaps = 9/128 (7%)
Query: 219 GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWV--HTGEGF 276
G +L + +LE G YAC V G T L+V PE+T+ R V
Sbjct: 4121 GATRELLIHQLEAKDTGEYAC-VTGGQK----TAASLRVT-EPEVTIVRGLVDAEVTADE 4174
Query: 277 RAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR-GSNHTLLIADVQPEDFGNYSCVA 335
E C V V W PL ++E ++ R G HTL + V PED G S
Sbjct: 4175 DVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHL 4234
Query: 336 DNSLGRAR 343
N A+
Sbjct: 4235 GNHASSAQ 4242
Score = 38.3 bits (85), Expect = 0.062
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
Query: 285 LADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
L+D A V+W ++ LS + + A LL+ DV +D G Y CV+ GR
Sbjct: 730 LSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRG--GRIAY 787
Query: 345 HVEVSG 350
+ V G
Sbjct: 788 QLSVQG 793
Score = 36.7 bits (81), Expect = 0.19
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 3/83 (3%)
Query: 265 VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQ 324
+E WV GE EL C L+ V W ++ + S++ + G+ L+I
Sbjct: 2833 LEDQWVAPGED--VELRCE-LSRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGAS 2889
Query: 325 PEDFGNYSCVADNSLGRARRHVE 347
+D G Y+C + S A HVE
Sbjct: 2890 LKDAGEYTCEVEASKSTASLHVE 2912
Score = 36.3 bits (80), Expect = 0.25
Identities = 55/218 (25%), Positives = 80/218 (36%), Gaps = 26/218 (11%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+ Y C I +R Q+ ++ V + V + G +A CR + V
Sbjct: 2981 DSDTYTCDIGQAQSRAQL----LVQGRRVHIIEDLEDVDVQEGSSATFRCRISPANYEPV 3036
Query: 207 TW---------HRLNDSSSRLGEGPQLQLSRLE-RHHGGVYACTVDNGVGPPV-VTEFQL 255
W + LN+ ++ G L L +L + G +Y D + VTE
Sbjct: 3037 HWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSGTIYFEAGDQRASAALRVTE--- 3093
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVC-TVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
P + E + EG LVC T D P V W ++ L S R +S G
Sbjct: 3094 ---KPSVFSRELTDATITEGEDLTLVCETSTCDIP--VCWTKDGKTLRGSARCQLSHEGH 3148
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRP 352
LLI +D G Y C A + + V V RP
Sbjct: 3149 RAQLLITGATLQDSGRYKCEAGGACSSS--IVRVHARP 3184
Score = 35.9 bits (79), Expect = 0.33
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
E R L C V + A+V W++ S L + + + G L+I+DV ED Y+C
Sbjct: 2303 EKHRGVLECQV-SRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTC 2361
Query: 334 VADNSLGRARRHVE 347
A + A+ VE
Sbjct: 2362 DAGDVKTSAQFFVE 2375
Score = 35.5 bits (78), Expect = 0.44
Identities = 56/214 (26%), Positives = 90/214 (42%), Gaps = 18/214 (8%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
F D G + C+ D + ++ TVE+ VR + V AR G A +E + + V
Sbjct: 2051 FADRGFFGCETPDDKTQAKL-TVEMR---QVRLVRGLQAVEAREQGTATMEVQLSHADVD 2106
Query: 205 TVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACT--VDNGV----GPPVVTEFQLQVL 258
+W R R +GP L+ H + D+G+ V T +L V
Sbjct: 2107 G-SWTR---DGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAEGVHTSARLVVT 2162
Query: 259 -YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
P + V T E + L C L+ P +V W ++ L A + + ++A+G+ +
Sbjct: 2163 ELPVSFSRPLQDVVTTEKEKVTLECE-LSRPNVDVRWLKDGVELRAGKTMAIAAQGACRS 2221
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR 351
L I + D G Y C A ++ A V+V GR
Sbjct: 2222 LTIYRCEFADQGVYVCDAHDAQSSA--SVKVQGR 2253
Score = 35.1 bits (77), Expect = 0.58
Identities = 16/47 (34%), Positives = 28/47 (59%), Gaps = 2/47 (4%)
Query: 308 TMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA--RRHVEVSGRP 352
T+++ H+L++ DV + G Y+C+A N+ G+A + VSG P
Sbjct: 5424 TVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLP 5470
Score = 34.3 bits (75), Expect = 1.0
Identities = 47/198 (23%), Positives = 74/198 (37%), Gaps = 20/198 (10%)
Query: 146 QDAGDYVC-------QISDRVARDQVHTVEVLVPPSVRASPETRH-VTARRGGAAVLECR 197
+D G+Y C S RV +V V LV V A + R GA ++
Sbjct: 4134 KDTGEYACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQWC 4193
Query: 198 AAGNPVPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
G P+ + + + + + R G L+L + G + + N +T
Sbjct: 4194 LQGLPLQS---NEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLT------ 4244
Query: 258 LYPPEITVERSW--VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA-RGS 314
+ PE+T+ V EG A C + E W PL A+E ++ +G+
Sbjct: 4245 VRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGT 4304
Query: 315 NHTLLIADVQPEDFGNYS 332
H L + V ED G S
Sbjct: 4305 LHLLTLHKVTLEDAGTVS 4322
Score = 33.9 bits (74), Expect = 1.3
Identities = 52/221 (23%), Positives = 80/221 (36%), Gaps = 24/221 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
QD+G Y C D+ T+ V P+ + + R+ A G A L C +
Sbjct: 3249 QDSGRYSCSFGDQTTSA---TLTVTALPA-QFIGKLRNKEATEGATATLRCELS--KAAP 3302
Query: 206 VTWHR----LNDSSSRL----GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V W + L D G +LQ+ L Y+C +T +
Sbjct: 3303 VEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLTIRPMPA 3362
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
+ + + S EG A L C + P E W + L +R ++ G+
Sbjct: 3363 HFIGRLRHQESI----EGATATLRCELSKAAPVE--WRKGRESLRDGDRHSLRQDGAVCE 3416
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFT 358
L I + D G YSCV G R ++ + PA+FT
Sbjct: 3417 LQICGLAVADAGEYSCVC----GEERTSATLTVKALPAKFT 3453
Score = 33.1 bits (72), Expect = 2.3
Identities = 27/93 (29%), Positives = 34/93 (36%), Gaps = 16/93 (17%)
Query: 168 EVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGP----- 222
E LVPP + + V ++G + + G PVPTV W R L GP
Sbjct: 5366 EQLVPPRMLERFTPKKV--KKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGY 5423
Query: 223 ---------QLQLSRLERHHGGVYACTVDNGVG 246
L L + R H G Y C N G
Sbjct: 5424 TVASSAQQHSLVLLDVGRQHQGTYTCIASNAAG 5456
>AJ314900-1|CAC85747.1| 551|Homo sapiens obscurin protein.
Length = 551
Score = 74.1 bits (174), Expect = 1e-12
Identities = 70/240 (29%), Positives = 103/240 (42%), Gaps = 31/240 (12%)
Query: 121 HTNVWETTRRITSEQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPE 180
H RR+ +Q G T DAGDY C+ + ++H E P + A +
Sbjct: 52 HVEAKGCRRRLVVQQAGKT-------DAGDYSCEARGQRVSFRLHITE---PKMMFAKEQ 101
Query: 181 TRH--VTARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRLG---EG--PQLQLSRLE 230
+ H V A G +A+L C A VTW++ SSS++G +G +L L +
Sbjct: 102 SVHNEVQAEAGASAMLSCEVA-QAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAG 160
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTG----EGFRAELVCTVLA 286
+ G Y+C G V F L + P + + VH G A L C V A
Sbjct: 161 KADAGEYSCEAG---GQRV--SFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEV-A 214
Query: 287 DPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
P EV+WY++ LS+S +V M +G L++ V D G YSC A + H+
Sbjct: 215 QPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHI 274
Score = 62.5 bits (145), Expect = 3e-09
Identities = 62/221 (28%), Positives = 91/221 (41%), Gaps = 29/221 (13%)
Query: 128 TRRITSEQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRH--VT 185
TRR+ +Q G DAG+Y C+ + Q+H E P +V A + H V
Sbjct: 243 TRRLVVQQVGKA-------DAGEYSCEAGGQRVSFQLHITE---PKAVFAKEQLVHNEVR 292
Query: 186 ARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRL-----GEGPQLQLSRLERHHGGVY 237
G +A L C A VTW++ SSS++ G QL + + + G Y
Sbjct: 293 TEAGASATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEY 351
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTV---LADPPAEVSW 294
C G + F L V P + + H A + T+ +A EV+W
Sbjct: 352 TCEAG---GQRL--SFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTW 406
Query: 295 YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
Y++ LS+S +V M A G L++ D G YSC A
Sbjct: 407 YKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA 447
Score = 56.0 bits (129), Expect = 3e-07
Identities = 59/210 (28%), Positives = 86/210 (40%), Gaps = 16/210 (7%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRH--VTARRGGAAVLECRAAGNPVP 204
DAG+Y C+ + R H ++V P +V A + H V A G A L C A
Sbjct: 347 DAGEYTCEAGGQ--RLSFH-LDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEVA-QAQT 402
Query: 205 TVTWHR----LNDSSS----RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
VTW++ L+ SS +G +L + + + G Y+C + + +
Sbjct: 403 EVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEAGGQRLSFSLDVAEPK 462
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
V++ E V R V G L C V A EV WY++ LS S +V M A G
Sbjct: 463 VVFAKEQPVHRE-VQAQAGASTTLSCEV-AQAQTEVMWYKDGKKLSFSSKVRMEAVGCTR 520
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHV 346
L++ G YSC A + HV
Sbjct: 521 RLVVQQAGQAVAGEYSCEAGSQRLSFHLHV 550
Score = 46.4 bits (105), Expect = 2e-04
Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
Query: 265 VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQ 324
V S V G A L C V A EV WY++ LS+S +V + A+G L++
Sbjct: 10 VAHSEVQAEAGASATLSCEV-AQAQTEVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAG 68
Query: 325 PEDFGNYSCVADNSLGRARRHV 346
D G+YSC A R H+
Sbjct: 69 KTDAGDYSCEARGQRVSFRLHI 90
>AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein.
Length = 6620
Score = 74.1 bits (174), Expect = 1e-12
Identities = 70/240 (29%), Positives = 103/240 (42%), Gaps = 31/240 (12%)
Query: 121 HTNVWETTRRITSEQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPE 180
H RR+ +Q G T DAGDY C+ + ++H E P + A +
Sbjct: 1029 HVEAKGCRRRLVVQQAGKT-------DAGDYSCEARGQRVSFRLHITE---PKMMFAKEQ 1078
Query: 181 TRH--VTARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRLG---EG--PQLQLSRLE 230
+ H V A G +A+L C A VTW++ SSS++G +G +L L +
Sbjct: 1079 SVHNEVQAEAGASAMLSCEVA-QAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAG 1137
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTG----EGFRAELVCTVLA 286
+ G Y+C G V F L + P + + VH G A L C V A
Sbjct: 1138 KADAGEYSCEAG---GQRV--SFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEV-A 1191
Query: 287 DPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
P EV+WY++ LS+S +V M +G L++ V D G YSC A + H+
Sbjct: 1192 QPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHI 1251
Score = 66.9 bits (156), Expect = 2e-10
Identities = 65/229 (28%), Positives = 96/229 (41%), Gaps = 23/229 (10%)
Query: 128 TRRITSEQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRAS--PETRHVT 185
TRR+ +Q G DAG+Y C+ + +H E P +V A P +R V
Sbjct: 1496 TRRLVVQQAGQA-------DAGEYSCEAGSQRLSFHLHVAE---PKAVFAKEQPASREVQ 1545
Query: 186 ARRGGAAVLECRAAGNPVPTVTWHR----LNDSSS----RLGEGPQLQLSRLERHHGGVY 237
A G +A L C A VTW++ L+ SS +G +L + + G Y
Sbjct: 1546 AEAGTSATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEY 1604
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQN 297
+C + + + +V++ E R V G A L C V A EV+WY++
Sbjct: 1605 SCKAGDQRLSFHLHVAEPKVVFAKEQPAHRE-VQAEAGASATLSCEV-AQAQTEVTWYKD 1662
Query: 298 SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
LS+S +V + A G L++ D G YSC A R HV
Sbjct: 1663 GKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRLHV 1711
Score = 62.5 bits (145), Expect = 3e-09
Identities = 62/221 (28%), Positives = 91/221 (41%), Gaps = 29/221 (13%)
Query: 128 TRRITSEQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRH--VT 185
TRR+ +Q G DAG+Y C+ + Q+H E P +V A + H V
Sbjct: 1220 TRRLVVQQVGKA-------DAGEYSCEAGGQRVSFQLHITE---PKAVFAKEQLVHNEVR 1269
Query: 186 ARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRL-----GEGPQLQLSRLERHHGGVY 237
G +A L C A VTW++ SSS++ G QL + + + G Y
Sbjct: 1270 TEAGASATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEY 1328
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTV---LADPPAEVSW 294
C G + F L V P + + H A + T+ +A EV+W
Sbjct: 1329 TCEAG---GQRL--SFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTW 1383
Query: 295 YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
Y++ LS+S +V M A G L++ D G YSC A
Sbjct: 1384 YKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA 1424
Score = 59.7 bits (138), Expect = 2e-08
Identities = 65/216 (30%), Positives = 89/216 (41%), Gaps = 26/216 (12%)
Query: 146 QDAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPET--RHVTARRGGAAVLECRAAGNP 202
QD G Y C RV D V + V P V A + R + A G +A L C A
Sbjct: 863 QDEGTYSC----RVGEDSVDFRLRVSEPKVVFAKEQLARRKLQAEAGASATLSCEVA-QA 917
Query: 203 VPTVTWHR----LNDSSSRLGEGP----QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
VTW++ L+ SS E +L + + + G Y+C G + F
Sbjct: 918 QTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAG---GQRL--SFH 972
Query: 255 LQVLYPPEI----TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS 310
L V P + V S V G A L C V A AEV WY++ LS+S +V +
Sbjct: 973 LDVKEPKVVFAKDQVAHSEVQAEAGANATLSCEV-AQAQAEVMWYKDGKKLSSSLKVHVE 1031
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
A+G L++ D G+YSC A R H+
Sbjct: 1032 AKGCRRRLVVQQAGKTDAGDYSCEARGQRVSFRLHI 1067
Score = 58.0 bits (134), Expect = 7e-08
Identities = 58/208 (27%), Positives = 80/208 (38%), Gaps = 20/208 (9%)
Query: 152 VCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRL 211
+C I R+A + V PP E TA G L CR G P P ++W++
Sbjct: 5999 ICGIQQRLA------LPVWRPPDFEE--ELADCTAELGETVKLACRVTGTPKPVISWYKD 6050
Query: 212 N-----DSSSRLGEGPQ----LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE 262
D L E P L L L G Y C + G T ++ V PP
Sbjct: 6051 GKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAG-NCSTLGKILVQVPPR 6109
Query: 263 ITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERV-TMS-ARGSNHTLLI 320
+ EG A+ CT+ P ++ WY++ L+ + T+S R L+I
Sbjct: 6110 FVNKVLASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVI 6169
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEV 348
ED G Y C N LG AR E+
Sbjct: 6170 RAASKEDLGLYECELVNRLGSARASAEL 6197
Score = 55.6 bits (128), Expect = 4e-07
Identities = 57/210 (27%), Positives = 82/210 (39%), Gaps = 18/210 (8%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D G+Y C R T+ V P V P + + A G A L+C + P TV
Sbjct: 3866 DTGEYSCVCGQE--RTSA-TLTVRAPQPVFREP-LQSLQAEEGSTATLQCELS-EPTATV 3920
Query: 207 TWHR----LNDSSSR----LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W + L + R G +L L L+R G Y CT + +T V
Sbjct: 3921 VWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTCTCGSQATSATLTVTAAPVR 3980
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
+ E+ + EG A L C L+ A V W + S L + M G+ L
Sbjct: 3981 FLRELQHQE----VDEGGTAHLCCE-LSRAGASVEWRKGSLQLFPCAKYQMVQDGAAAEL 4035
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEV 348
L+ V+ ED G+Y+C ++ A V V
Sbjct: 4036 LVRGVEQEDAGDYTCDTGHTQSMASLSVRV 4065
Score = 54.8 bits (126), Expect = 7e-07
Identities = 53/208 (25%), Positives = 84/208 (40%), Gaps = 12/208 (5%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D G+Y C+ + + E V + P R V A+ G + L C A V
Sbjct: 1416 DTGEYSCEAGGQRLSFSLDVAEPKVV-FAKEQPVHREVQAQAGASTTLSCEVA-QAQTEV 1473
Query: 207 TWHR----LNDSSS----RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W++ L+ SS +G +L + + + G Y+C + + + + +
Sbjct: 1474 MWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQADAGEYSCEAGSQRLSFHLHVAEPKAV 1533
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
+ E R V G A L C V A EV+WY++ LS+S +V M A G L
Sbjct: 1534 FAKEQPASRE-VQAEAGTSATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRL 1591
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHV 346
++ + D G YSC A + HV
Sbjct: 1592 VVQEAGQADAGEYSCKAGDQRLSFHLHV 1619
Score = 53.2 bits (122), Expect = 2e-06
Identities = 51/197 (25%), Positives = 79/197 (40%), Gaps = 15/197 (7%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG+Y C+ D+ +H E V + P R V A G +A L C A V
Sbjct: 1600 DAGEYSCKAGDQRLSFHLHVAEPKVV-FAKEQPAHREVQAEAGASATLSCEVA-QAQTEV 1657
Query: 207 TWHR----LNDSSS----RLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
TW++ L+ SS +G +L + + + G Y+C G + + L
Sbjct: 1658 TWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAG---GQRLSFRLHVAEL 1714
Query: 259 YPP--EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
P E R + E L T+ A V+W ++ + S+R +++G H
Sbjct: 1715 EPQISERPCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTH 1774
Query: 317 TLLIADVQPEDFGNYSC 333
TL + Q D YSC
Sbjct: 1775 TLTVHGAQVLDSAIYSC 1791
Score = 52.8 bits (121), Expect = 3e-06
Identities = 54/201 (26%), Positives = 83/201 (41%), Gaps = 13/201 (6%)
Query: 183 HVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVY----- 237
+V A GG A+ EC+ + V TW L+D R E ++ H +
Sbjct: 4348 NVEALEGGEALFECQLSQPEVAAHTW-LLDDEPVRTSENAEVVFFENGLRHLLLLKNLRP 4406
Query: 238 --ACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVL-ADPPAEVSW 294
+C V G V + F + EI G +A CT+ A P E SW
Sbjct: 4407 QDSCRVTFLAGDMVTSAFLTVRGWRLEILEPLKNAAVRAGAQARFTCTLSEAVPVGEASW 4466
Query: 295 YQNSFPLSASERV-TMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
Y N + + T++A GS+ LL+ QP G + +++ AR + V G P
Sbjct: 4467 YINGAAVQPDDSDWTVTADGSHQALLLRSAQPHHAGEVTFACRDAVASAR--LTVLGLPD 4524
Query: 354 PARFTSPPLARAPHSYTLSFA 374
P + +A + H+ TLS+A
Sbjct: 4525 PPE-DAEVVAHSSHTVTLSWA 4544
Score = 52.4 bits (120), Expect = 4e-06
Identities = 64/284 (22%), Positives = 111/284 (39%), Gaps = 28/284 (9%)
Query: 102 TIYENSETSVALAILGATGHTNVWETTRRITSE-------QHGNTNF--RMIF---QDAG 149
T+ E ++ + G VW+ ++ +E + NF +++F D G
Sbjct: 248 TVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRG 307
Query: 150 DYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWH 209
Y C S+ V + + V+ P+V + + R +A C P W
Sbjct: 308 LYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVP-QPSTEAAWF 366
Query: 210 RLND---SSSRLG---EGPQLQLS--RLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP 261
+ +S++ G EG + +L+ + VY C G V E +Q
Sbjct: 367 KEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEG--SRTVAELAVQGNLLR 424
Query: 262 EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIA 321
++ ++ V G+ + C LA P V W +N + A RV +SA G+ HTL I+
Sbjct: 425 KLP-RKTAVRVGD---TAMFCVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTIS 480
Query: 322 DVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARA 365
ED G + +A + R V +P P + P+ +A
Sbjct: 481 QCCLEDVGQVAFMAGDCQTSTRFCVSAPRKP-PLQPPVDPVVKA 523
Score = 52.0 bits (119), Expect = 5e-06
Identities = 49/171 (28%), Positives = 67/171 (39%), Gaps = 18/171 (10%)
Query: 189 GGAAVLECRAAGNPVPTVTWHR-----LNDSSSRLG-EGPQLQLSRLERHHG--GVYACT 240
G A L C+ GNP P V+W + + RL +G +L+ L+ G G Y C
Sbjct: 24 GKDATLSCQIVGNPTPQVSWEKDQQPVTAGARFRLAQDGDLYRLTILDLALGDSGQYVCR 83
Query: 241 VDNGVGPPVVTEFQLQV-------LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS 293
N +G LQV P + + + EG A C V P VS
Sbjct: 84 ARNAIG-EAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVS 142
Query: 294 WYQNSFPLSASE--RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
W ++ L + RV + G L I +P D G Y A+N LG A
Sbjct: 143 WSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAA 193
Score = 51.2 bits (117), Expect = 8e-06
Identities = 53/211 (25%), Positives = 85/211 (40%), Gaps = 17/211 (8%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+DAG+YVC+ D Q+ V VP V+ V A GG A +C + + V
Sbjct: 1873 EDAGEYVCESRDDHTSAQL---TVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDV-A 1928
Query: 206 VTWHR----LNDSS----SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V W R L S S+ G L +S L G + + + V
Sbjct: 1929 VVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVREAPV 1988
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
L+ ++ E V E+ T P E+ W +N+ L+ + V + A G+ H
Sbjct: 1989 LFKKKL--EPQTVEERSSVTLEVELT---RPWPELRWTRNATALAPGKNVEIHAEGARHR 2043
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
L++ +V D G + C + +A+ VE+
Sbjct: 2044 LVLHNVGFADRGFFGCETPDDKTQAKLTVEM 2074
Score = 50.0 bits (114), Expect = 2e-05
Identities = 52/195 (26%), Positives = 78/195 (40%), Gaps = 19/195 (9%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG+Y C + + TV L R + ++ AR G AVL+C + V
Sbjct: 3778 DAGEYSC-VCGQERTSATLTVRAL---PARFIEDVKNQEAREGATAVLQCELS--KAAPV 3831
Query: 207 TWH------RLNDSSSRLGEGP--QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W R D S +G +LQ+ L G Y+C +T Q +
Sbjct: 3832 EWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQPV 3891
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
+ + + EG A L C L++P A V W + L A+ R +G L
Sbjct: 3892 FREPLQS----LQAEEGSTATLQCE-LSEPTATVVWSKGGLQLQANGRREPRLQGCTAEL 3946
Query: 319 LIADVQPEDFGNYSC 333
++ D+Q ED G Y+C
Sbjct: 3947 VLQDLQREDTGEYTC 3961
Score = 47.6 bits (108), Expect = 1e-04
Identities = 50/199 (25%), Positives = 78/199 (39%), Gaps = 20/199 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+D G+Y C + T+ V P VR E +H GG A L C + +
Sbjct: 3954 EDTGEYTCTCGSQATSA---TLTVTAAP-VRFLRELQHQEVDEGGTAHLCCELS-RAGAS 4008
Query: 206 VTWHR--------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V W + + G +L + +E+ G Y C D G + + L V
Sbjct: 4009 VEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTC--DTGHTQSMAS---LSV 4063
Query: 258 LYP-PEITVERSWVHTGEGFRAELVCTVL-ADPPAEVSWYQNSFPLSASERVTMSARGSN 315
P P+ + G A L C + A+ A V W + L A + M ++G+
Sbjct: 4064 RVPRPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGAT 4123
Query: 316 HTLLIADVQPEDFGNYSCV 334
LLI ++ +D G Y+CV
Sbjct: 4124 RELLIHQLEAKDTGEYACV 4142
Score = 46.8 bits (106), Expect = 2e-04
Identities = 41/142 (28%), Positives = 59/142 (41%), Gaps = 9/142 (6%)
Query: 272 TGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNY 331
TG ++ ++ P V WY++ PLS SE+ MS G L I + P D G Y
Sbjct: 2479 TGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVY 2538
Query: 332 SCVADNSLGRARRHVEVSGRPGPARFTSP-PLARAPHSYTLSFAVDSYPPLDELRLLYRQ 390
C A G A EV+ T P A A SF+ + +E+
Sbjct: 2539 RCQA----GSAHSSTEVTVEAREVTVTGPLQDAEATEEGWASFSCELSHEDEEVEWSLNG 2594
Query: 391 LAI-NESFQQ---PGRWHDVVL 408
+ + N+SF + GR H +VL
Sbjct: 2595 MPLYNDSFHEISHKGRRHTLVL 2616
Score = 46.8 bits (106), Expect = 2e-04
Identities = 58/220 (26%), Positives = 82/220 (37%), Gaps = 23/220 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
QD+G Y C+ + V V P VR + + GGAA L C + P
Sbjct: 3160 QDSGRYKCEAGGACSSS---IVRVHARP-VRFQEALKDLEVLEGGAATLRCVLSSVAAP- 3214
Query: 206 VTWH------RLNDSSSRLGEGPQLQL--SRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V W R D S EG L+L L G Y+C+ + +T L
Sbjct: 3215 VKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSCSFGDQTTSATLTVTALPA 3274
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
+ ++ + + EG A L C + P E W + S L +R + G+
Sbjct: 3275 QFIGKLRNKEAT----EGATATLRCELSKTAPVE--WRKGSETLRDGDRYCLRQDGAMCE 3328
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF 357
L I + D YSCV G R ++ RP PA F
Sbjct: 3329 LQIRGLAMVDAAEYSCVC----GEERTSASLTIRPMPAHF 3364
Score = 46.8 bits (106), Expect = 2e-04
Identities = 54/219 (24%), Positives = 88/219 (40%), Gaps = 24/219 (10%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG+Y+C + + T+ L R + ++ AR G AVL+C N V
Sbjct: 3514 DAGEYLC-VCGQERTSATLTIRAL---PARFIEDVKNQEAREGATAVLQCEL--NSAAPV 3567
Query: 207 TWHR----LND----SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W + L D S + G +LQ+ L G Y+C ++T L +
Sbjct: 3568 EWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRALPIK 3627
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
+ + E + EG A L C + P E W++ L +R ++ G+ L
Sbjct: 3628 FTEGLRNEEAT----EGATAVLRCELSKMAPVE--WWKGHETLRDGDRHSLRQDGARCEL 3681
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF 357
I + ED G Y C+ G+ R ++ R P++F
Sbjct: 3682 QIRGLVAEDAGEYLCMC----GKERTSAMLTVRAMPSKF 3716
Score = 46.0 bits (104), Expect = 3e-04
Identities = 44/172 (25%), Positives = 68/172 (39%), Gaps = 14/172 (8%)
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHR---LNDSSSR--LGEGPQ---- 223
P+ S TR T G A L C G P P W + L R + E Q
Sbjct: 236 PASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFV 295
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSW--VHTGEGFRAELV 281
L++ ++ G+Y CT N VG + L V+ P + ++ + E A +
Sbjct: 296 LKILFCKQSDRGLYTCTASNLVGQTYSS--VLVVVREPAVPFKKRLQDLEVREKESATFL 353
Query: 282 CTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
C V P E +W++ L AS + + G+ L + +V +D Y C
Sbjct: 354 CEV-PQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYIC 404
Score = 44.8 bits (101), Expect = 7e-04
Identities = 36/144 (25%), Positives = 59/144 (40%), Gaps = 8/144 (5%)
Query: 210 RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP----PEITV 265
R + + LG G +++L +E+ V C + PVV L L P
Sbjct: 5074 RFQEMFATLGIGVEIKL--VEQGPRRVEMC-ISKETPAPVVPPEPLPSLLTSDAAPVFLT 5130
Query: 266 ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA-RGSNHTLLIADVQ 324
E +G+ C V P V W+++ L + ++ + H L+I V
Sbjct: 5131 ELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVV 5190
Query: 325 PEDFGNYSCVADNSLGRARRHVEV 348
P D G Y C+A+NS+G + E+
Sbjct: 5191 PADMGVYRCLAENSMGVSSTKAEL 5214
Score = 44.4 bits (100), Expect = 0.001
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Query: 261 PEITVERSWVHTGEGFR-AELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
P++ E + G R A+ V P + W+++ PL+AS + M+ + HTL
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLE 5319
Query: 320 IADVQPEDFGNYSCVADNSLGRA 342
I V ED G Y+ N++G A
Sbjct: 5320 IISVTREDSGQYAAYISNAMGAA 5342
Score = 44.0 bits (99), Expect = 0.001
Identities = 51/212 (24%), Positives = 81/212 (38%), Gaps = 19/212 (8%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+DAG+Y C++ + +H E + + E ++ G AV C+ +P T
Sbjct: 2891 KDAGEYTCEVEASKSTASLHVEE----KANCFTEELTNLQVEEKGTAVFTCKTE-HPAAT 2945
Query: 206 VTWHR----LNDSS----SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
VTW + L S S+ G +L +S LE+ Y C + + +V
Sbjct: 2946 VTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRV 3005
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR-GSNH 316
I + V EG A C + V W+ + PL A+E + A+ G H
Sbjct: 3006 ----HIIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYH 3061
Query: 317 TLLIADVQPEDFGN-YSCVADNSLGRARRHVE 347
L + + +D G Y D A R E
Sbjct: 3062 VLTLRQLALKDSGTIYFEAGDQRASAALRVTE 3093
Score = 43.6 bits (98), Expect = 0.002
Identities = 56/214 (26%), Positives = 82/214 (38%), Gaps = 20/214 (9%)
Query: 142 RMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGN 201
R++ DAG Y CQ + +V TVE V + + A G A C +
Sbjct: 2529 RLMPADAGVYRCQAGSAHSSTEV-TVEAR---EVTVTGPLQDAEATEEGWASFSCELSHE 2584
Query: 202 PVPTVTWHR-----LNDSS---SRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
V W NDS S G L L ++R G+ + V T
Sbjct: 2585 D-EEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRAS-----SLKVSTSA 2638
Query: 254 QLQVLYPPEITVER-SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
+L+V P + ++ + E L C V +DP A V W ++ L S++
Sbjct: 2639 RLEVRVKPVVFLKALDDLSAEERGTLALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHT 2697
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
L++ DV PED G Y+C + RAR V
Sbjct: 2698 AGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRV 2731
Score = 42.3 bits (95), Expect = 0.004
Identities = 74/273 (27%), Positives = 101/273 (36%), Gaps = 36/273 (13%)
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLG-------EGP--QLQLSRLERHHG 234
V GG L C + V W R ++ R+G EGP L + L
Sbjct: 1818 VCGELGGTVTLACELSP-ACAEVVW-RCGNTQPRVGKRFQMVAEGPVRSLTVLGLRAEDA 1875
Query: 235 GVYACTVDNGVGPPVVTEFQLQVLYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEV 292
G Y C + T QL V P + S V EG A C V A V
Sbjct: 1876 GEYVCESRDDH-----TSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDVAVV 1930
Query: 293 SWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRP 352
W+++ L SE+ +S G++H+L I+D+ ED G + A+ + A V R
Sbjct: 1931 -WFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRV----RE 1985
Query: 353 GPARF---TSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLA 409
P F P S TL V+ P ELR A+ PG+ +V +
Sbjct: 1986 APVLFKKKLEPQTVEERSSVTLE--VELTRPWPELRWTRNATAL-----APGK--NVEIH 2036
Query: 410 APAAKGSLT-HRVSHELRGLQPAAVYEAIVQAK 441
A A+ L H V RG + QAK
Sbjct: 2037 AEGARHRLVLHNVGFADRGFFGCETPDDKTQAK 2069
Score = 40.7 bits (91), Expect = 0.012
Identities = 54/220 (24%), Positives = 85/220 (38%), Gaps = 24/220 (10%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG+Y C + + TV+ L + + R+ A G A+L C + V V
Sbjct: 3426 DAGEYSCVCGEERTSATL-TVKAL---PAKFTEGLRNEEAVEGATAMLWCELS--KVAPV 3479
Query: 207 TWHR----LNDSSSRL----GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W + L D + G +LQ+ L G Y C +T L
Sbjct: 3480 EWRKGPENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATLTIRALPAR 3539
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
+ ++ + + EG A L C + + P E W + S L +R ++ G+ L
Sbjct: 3540 FIEDVKNQEA----REGATAVLQCELNSAAPVE--WRKGSETLRDGDRYSLRQDGTKCEL 3593
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFT 358
I + D G YSCV G+ R ++ R P +FT
Sbjct: 3594 QIRGLAMADTGEYSCVC----GQERTSAMLTVRALPIKFT 3629
Score = 40.3 bits (90), Expect = 0.015
Identities = 48/198 (24%), Positives = 76/198 (38%), Gaps = 16/198 (8%)
Query: 143 MIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAA-GN 201
++ +DAG+Y+C + + TV + + R+ A G A L C +
Sbjct: 3686 LVAEDAGEYLCMCG-KERTSAMLTVRAMPSKFIEG---LRNEEATEGDTATLWCELSKAA 3741
Query: 202 PVPTVTWH---RLNDSSSRLGEGP--QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
PV H R D S +G +LQ+ L G Y+C +T L
Sbjct: 3742 PVEWRKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEYSCVCGQERTSATLTVRALP 3801
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
+ ++ + + EG A L C + P E W + S L +R ++ G+
Sbjct: 3802 ARFIEDVKNQEA----REGATAVLQCELSKAAPVE--WRKGSETLRGGDRYSLRQDGTRC 3855
Query: 317 TLLIADVQPEDFGNYSCV 334
L I + D G YSCV
Sbjct: 3856 ELQIHGLSVADTGEYSCV 3873
Score = 39.5 bits (88), Expect = 0.027
Identities = 29/117 (24%), Positives = 45/117 (38%), Gaps = 18/117 (15%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRH-------VTARRGGAAVLECRAA 199
D+G YVC+ + + + V + V + + H + R G A CR
Sbjct: 76 DSGQYVCRARNAIG-EAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVG 134
Query: 200 GNPVPTVTW----HRLNDSS------SRLGEGPQLQLSRLERHHGGVYACTVDNGVG 246
G+P P V+W RL + LGE L++ GG Y +N +G
Sbjct: 135 GSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLG 191
Score = 39.5 bits (88), Expect = 0.027
Identities = 48/206 (23%), Positives = 79/206 (38%), Gaps = 18/206 (8%)
Query: 136 HGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLE 195
H T ++ +D+G + D+ A + E PSV S E T G L
Sbjct: 3061 HVLTLRQLALKDSGTIYFEAGDQRASAALRVTE---KPSV-FSRELTDATITEGEDLTLV 3116
Query: 196 CRAAGNPVPTVTWHR----LNDSS----SRLGEGPQLQLSRLERHHGGVYACTVDNGVGP 247
C + +P + W + L S+ S G QL ++ G Y C
Sbjct: 3117 CETSTCDIP-MCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSS 3175
Query: 248 PVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERV 307
+V V + + + EG A L C VL+ A V W + L ++
Sbjct: 3176 SIVRVHARPVRFQEALKD----LEVLEGGAATLRC-VLSSVAAPVKWCYGNNVLRPGDKY 3230
Query: 308 TMSARGSNHTLLIADVQPEDFGNYSC 333
++ G+ L++ +++P+D G YSC
Sbjct: 3231 SLRQEGAMLELVVRNLRPQDSGRYSC 3256
Score = 39.5 bits (88), Expect = 0.027
Identities = 39/128 (30%), Positives = 51/128 (39%), Gaps = 9/128 (7%)
Query: 219 GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWV--HTGEGF 276
G +L + +LE G YAC V G T L+V PE+T+ R V
Sbjct: 4121 GATRELLIHQLEAKDTGEYAC-VTGGQK----TAASLRVT-EPEVTIVRGLVDAEVTADE 4174
Query: 277 RAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR-GSNHTLLIADVQPEDFGNYSCVA 335
E C V V W PL ++E ++ R G HTL + V PED G S
Sbjct: 4175 DVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHL 4234
Query: 336 DNSLGRAR 343
N A+
Sbjct: 4235 GNHASSAQ 4242
Score = 38.3 bits (85), Expect = 0.062
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
Query: 285 LADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
L+D A V+W ++ LS + + A LL+ DV +D G Y CV+ GR
Sbjct: 730 LSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRG--GRIAY 787
Query: 345 HVEVSG 350
+ V G
Sbjct: 788 QLSVQG 793
Score = 36.7 bits (81), Expect = 0.19
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 3/83 (3%)
Query: 265 VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQ 324
+E WV GE EL C L+ V W ++ + S++ + G+ L+I
Sbjct: 2833 LEDQWVAPGED--VELRCE-LSRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGAS 2889
Query: 325 PEDFGNYSCVADNSLGRARRHVE 347
+D G Y+C + S A HVE
Sbjct: 2890 LKDAGEYTCEVEASKSTASLHVE 2912
Score = 35.9 bits (79), Expect = 0.33
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
E R L C V + A+V W++ S L + + + G L+I+DV ED Y+C
Sbjct: 2303 EKHRGVLECQV-SRASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTC 2361
Query: 334 VADNSLGRARRHVE 347
A + A+ VE
Sbjct: 2362 DAGDVKTSAQFFVE 2375
Score = 35.5 bits (78), Expect = 0.44
Identities = 56/214 (26%), Positives = 90/214 (42%), Gaps = 18/214 (8%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
F D G + C+ D + ++ TVE+ VR + V AR G A +E + + V
Sbjct: 2051 FADRGFFGCETPDDKTQAKL-TVEMR---QVRLVRGLQAVEAREQGTATMEVQLSHADVD 2106
Query: 205 TVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACT--VDNGV----GPPVVTEFQLQVL 258
+W R R +GP L+ H + D+G+ V T +L V
Sbjct: 2107 G-SWTR---DGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAEGVHTSARLVVT 2162
Query: 259 -YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
P + V T E + L C L+ P +V W ++ L A + + ++A+G+ +
Sbjct: 2163 ELPVSFSRPLQDVVTTEKEKVTLECE-LSRPNVDVRWLKDGVELRAGKTMAIAAQGACRS 2221
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR 351
L I + D G Y C A ++ A V+V GR
Sbjct: 2222 LTIYRCEFADQGVYVCDAHDAQSSA--SVKVQGR 2253
Score = 35.1 bits (77), Expect = 0.58
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 3/74 (4%)
Query: 268 SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS-ERVTMSARGSNHTLLIADVQPE 326
S V G A+ C ++ V WY++ L S ER G+ H L+ A V +
Sbjct: 805 SCVDAVAGGPAQFECET-SEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQ 863
Query: 327 DFGNYSC-VADNSL 339
D G YSC V ++S+
Sbjct: 864 DEGTYSCRVGEDSV 877
Score = 35.1 bits (77), Expect = 0.58
Identities = 54/218 (24%), Positives = 80/218 (36%), Gaps = 26/218 (11%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+ Y C I +R Q+ ++ V + V + G +A CR + V
Sbjct: 2981 DSDTYTCDIGQAQSRAQL----LVQGRRVHIIEDLEDVDVQEGSSATFRCRISPANYEPV 3036
Query: 207 TW---------HRLNDSSSRLGEGPQLQLSRLE-RHHGGVYACTVDNGVGPPV-VTEFQL 255
W + LN+ ++ G L L +L + G +Y D + VTE
Sbjct: 3037 HWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSGTIYFEAGDQRASAALRVTE--- 3093
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVC-TVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
P + E + EG LVC T D P + W ++ L S R +S G
Sbjct: 3094 ---KPSVFSRELTDATITEGEDLTLVCETSTCDIP--MCWTKDGKTLRGSARCQLSHEGH 3148
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRP 352
LLI +D G Y C A + + V V RP
Sbjct: 3149 RAQLLITGATLQDSGRYKCEAGGACSSS--IVRVHARP 3184
Score = 35.1 bits (77), Expect = 0.58
Identities = 16/47 (34%), Positives = 28/47 (59%), Gaps = 2/47 (4%)
Query: 308 TMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA--RRHVEVSGRP 352
T+++ H+L++ DV + G Y+C+A N+ G+A + VSG P
Sbjct: 5424 TVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLP 5470
Score = 34.3 bits (75), Expect = 1.0
Identities = 47/198 (23%), Positives = 74/198 (37%), Gaps = 20/198 (10%)
Query: 146 QDAGDYVC-------QISDRVARDQVHTVEVLVPPSVRASPETRH-VTARRGGAAVLECR 197
+D G+Y C S RV +V V LV V A + R GA ++
Sbjct: 4134 KDTGEYACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQWC 4193
Query: 198 AAGNPVPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
G P+ + + + + + R G L+L + G + + N +T
Sbjct: 4194 LQGLPLQS---NEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLT------ 4244
Query: 258 LYPPEITVERSW--VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA-RGS 314
+ PE+T+ V EG A C + E W PL A+E ++ +G+
Sbjct: 4245 VRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGT 4304
Query: 315 NHTLLIADVQPEDFGNYS 332
H L + V ED G S
Sbjct: 4305 LHLLTLHKVTLEDAGTVS 4322
Score = 33.9 bits (74), Expect = 1.3
Identities = 52/221 (23%), Positives = 80/221 (36%), Gaps = 24/221 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
QD+G Y C D+ T+ V P+ + + R+ A G A L C +
Sbjct: 3249 QDSGRYSCSFGDQTTSA---TLTVTALPA-QFIGKLRNKEATEGATATLRCELS--KTAP 3302
Query: 206 VTWHR----LNDSSSRL----GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
V W + L D G +LQ+ L Y+C +T +
Sbjct: 3303 VEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLTIRPMPA 3362
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
+ + + S EG A L C + P E W + L +R ++ G+
Sbjct: 3363 HFIGRLRHQESI----EGATATLRCELSKAAPVE--WRKGRESLRDGDRHSLRQDGAVCE 3416
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFT 358
L I + D G YSCV G R ++ + PA+FT
Sbjct: 3417 LQICGLAVADAGEYSCVC----GEERTSATLTVKALPAKFT 3453
Score = 33.1 bits (72), Expect = 2.3
Identities = 27/93 (29%), Positives = 34/93 (36%), Gaps = 16/93 (17%)
Query: 168 EVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGP----- 222
E LVPP + + V ++G + + G PVPTV W R L GP
Sbjct: 5366 EQLVPPRMLERFTPKKV--KKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGY 5423
Query: 223 ---------QLQLSRLERHHGGVYACTVDNGVG 246
L L + R H G Y C N G
Sbjct: 5424 TVASSAQQHSLVLLDVGRQHQGTYTCIASNAAG 5456
>AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein.
Length = 1651
Score = 73.7 bits (173), Expect = 1e-12
Identities = 62/223 (27%), Positives = 94/223 (42%), Gaps = 15/223 (6%)
Query: 147 DAGDYVCQISDRVARDQVH--TVEV-LVPPSVRASPETRHVTARRGGAAVLECRAA-GNP 202
D G YVC + + H ++EV ++ R +P V G AV+EC+ G+P
Sbjct: 141 DEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAV--GEPAVMECQPPRGHP 198
Query: 203 VPTVTWHR----LNDSSSRLG-EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
PT++W + L+D R+ G +L ++ + G Y C N VG +L V
Sbjct: 199 EPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTV 258
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
L P S + AE C DP V W ++ L S +HT
Sbjct: 259 LERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRD----DHT 314
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
L I V D G+Y+CVA+N +G+A ++ + P P
Sbjct: 315 LKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKP 357
Score = 58.4 bits (135), Expect = 5e-08
Identities = 79/337 (23%), Positives = 131/337 (38%), Gaps = 43/337 (12%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C + V + + T+ V PP P + V G +C A GNP P
Sbjct: 324 DMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVAL--GRTVTFQCEATGNPQPA 381
Query: 206 VTWHRLN-----------DSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
+ W R SSSR + + L ++ ++R G Y C N G ++T+
Sbjct: 382 IFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAG-SIITK 440
Query: 253 FQLQVL-----YPPEITVERSWVHTGEGFRAELV--CTVLADPPAEVSWYQNSFPLSASE 305
L+V PP + + + V+ V C P + W ++ +S +
Sbjct: 441 AYLEVTDVIADRPPPV-IRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQD 499
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA--RRHVEVSGRPGPARFTSPPLA 363
+ + N L I + D G Y+C+A G A ++EV P + PP
Sbjct: 500 --SRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQ---PPRP 554
Query: 364 RAPHSYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAA-PAAKGSLTHRVS 422
P+ L + S P + ++ L+ + ++ A A GS V+
Sbjct: 555 TDPN---LIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVA 611
Query: 423 HE-------LRGLQPAAVYEAIVQAKNRYGWNEVSDI 452
++GL+P A+Y +V+A N YG ++ S I
Sbjct: 612 ENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQI 648
Score = 54.0 bits (124), Expect = 1e-06
Identities = 55/193 (28%), Positives = 76/193 (39%), Gaps = 24/193 (12%)
Query: 172 PPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHR--------LNDSSSRLGEGPQ 223
PP + P V+ +G A L C+A G P PT+ W++ +D S P
Sbjct: 67 PPRIVEHPSDLIVS--KGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPS 124
Query: 224 LQLSRLERHHG-------GVYACTVDNGVGPPVVTEFQLQV-LYPPEITVERSWVHTGEG 275
L L HG GVY C N +G V L+V + + S V G
Sbjct: 125 GSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVG 184
Query: 276 FRAELVC-TVLADPPAEVSWYQNSFPL-SASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
A + C P +SW ++ PL ER+T+ RG L+I + D G Y C
Sbjct: 185 EPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITI--RGGK--LMITYTRKSDAGKYVC 240
Query: 334 VADNSLGRARRHV 346
V N +G V
Sbjct: 241 VGTNMVGERESEV 253
Score = 41.9 bits (94), Expect = 0.005
Identities = 34/135 (25%), Positives = 55/135 (40%), Gaps = 16/135 (11%)
Query: 126 ETTRRITSEQHGNTNFRMIFQ-DAGDYVCQI----SDRVARDQVHTVEVLV---PPSVRA 177
+++ R + Q G+ + + D G Y+CQ + + + +V+ PP +R
Sbjct: 400 QSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQ 459
Query: 178 SPETRHVTARRGGAAVLECRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLER 231
P + V G VL C A G+PVPT+ W + DS + E LQ+ +
Sbjct: 460 GPVNQTVAV--DGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKL 517
Query: 232 HHGGVYACTVDNGVG 246
G Y C G
Sbjct: 518 GDTGRYTCIASTPSG 532
Score = 31.9 bits (69), Expect = 5.4
Identities = 28/94 (29%), Positives = 36/94 (38%), Gaps = 7/94 (7%)
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR-----G 313
+PP I S + +G A L C P + WY+ + + S R G
Sbjct: 66 FPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSG 125
Query: 314 SNHTLLIADVQPE--DFGNYSCVADNSLGRARRH 345
S L I + D G Y CVA N LG A H
Sbjct: 126 SLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSH 159
>U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 73.3 bits (172), Expect = 2e-12
Identities = 68/244 (27%), Positives = 102/244 (41%), Gaps = 23/244 (9%)
Query: 147 DAGDYVCQIS-DRVARDQVHTVEVLVP--PSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D G Y C + + + T +++V P + PE V A G A+L C + V
Sbjct: 123 DEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYA--GNNAILNCEVNADLV 180
Query: 204 PTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P V W + L+D +L G L +S GG+Y C V++G P E +L+V
Sbjct: 181 PFVRWEQNRQPLLLDDRVIKLPSG-MLVISNATEGDGGLYRCVVESGGPPKYSDEVELKV 239
Query: 258 LYPPEITVERSWVHTGE------GFRAELVCTVLADPPAEVSWYQNSFPL--SASERVTM 309
L PE+ + ++ G L C P + W +N L +SER+ +
Sbjct: 240 LPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVL 299
Query: 310 SARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSY 369
A GS L I+DV +D G Y C+ADN E++ + P P A S
Sbjct: 300 LAGGS---LEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESM 356
Query: 370 TLSF 373
+ F
Sbjct: 357 DIVF 360
Score = 72.5 bits (170), Expect = 3e-12
Identities = 70/276 (25%), Positives = 108/276 (39%), Gaps = 27/276 (9%)
Query: 189 GGAAVLECRAAGNPVPTVTWHRLND-----SSSRLG--EGPQLQLSRLERHHGGVYACTV 241
G VL C A+G P PT+ W + + SS RL G L++S + G Y C
Sbjct: 263 GQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIA 322
Query: 242 DNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL 301
DNG + + +L V PE + + ++ E C V P V W +N +
Sbjct: 323 DNG-NETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMV 381
Query: 302 SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE-VSGRPGPARFTSP 360
S+ + H L + + D G Y C+A+N +G A+ + + PA T+
Sbjct: 382 IPSDYFKIV---KEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPA--TTG 436
Query: 361 PLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAAPAAKGSLTHR 420
PL AP S + ++L +R A + + V
Sbjct: 437 PLPSAPRDVVASLVSTRF-----IKLTWRTPASDP--HGDNLTYSVFYTKEGIARERVEN 489
Query: 421 VSH------ELRGLQPAAVYEAIVQAKNRYGWNEVS 450
SH ++ L PA VY V A+N++G E S
Sbjct: 490 TSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESS 525
Score = 44.8 bits (101), Expect = 7e-04
Identities = 44/163 (26%), Positives = 65/163 (39%), Gaps = 16/163 (9%)
Query: 188 RGGAAVLECRAAGNPVPTVTWHR-------LNDSSSRLGEGPQLQLSRL--ERHH---GG 235
RG + +L C A P P + W + ++D +L L +S + +H+ G
Sbjct: 66 RGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEG 125
Query: 236 VYACTVD-NGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSW 294
Y C +G + +L V P T + G A L C V AD V W
Sbjct: 126 YYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRW 185
Query: 295 YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADN 337
QN PL +RV G L+I++ D G Y CV ++
Sbjct: 186 EQNRQPLLLDDRVIKLPSG---MLVISNATEGDGGLYRCVVES 225
Score = 43.6 bits (98), Expect = 0.002
Identities = 32/109 (29%), Positives = 46/109 (42%), Gaps = 14/109 (12%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPE----TRHVTARRGGAAVLECRAAGNP 202
DAG Y C +A + T+E +V+A PE ++ A V EC G P
Sbjct: 314 DAGTYFC-----IADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKP 368
Query: 203 VPTVTWHRLND-----SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVG 246
PTV W + D ++ + LQ+ L + G Y C +N VG
Sbjct: 369 TPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVG 417
>BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1
(chicken) protein.
Length = 1461
Score = 73.3 bits (172), Expect = 2e-12
Identities = 68/244 (27%), Positives = 102/244 (41%), Gaps = 23/244 (9%)
Query: 147 DAGDYVCQIS-DRVARDQVHTVEVLVP--PSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D G Y C + + + T +++V P + PE V A G A+L C + V
Sbjct: 123 DEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYA--GNNAILNCEVNADLV 180
Query: 204 PTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
P V W + L+D +L G L +S GG+Y C V++G P E +L+V
Sbjct: 181 PFVRWEQNRQPLLLDDRVIKLPSG-MLVISNATEGDGGLYRCVVESGGPPKYSDEVELKV 239
Query: 258 LYPPEITVERSWVHTGE------GFRAELVCTVLADPPAEVSWYQNSFPL--SASERVTM 309
L PE+ + ++ G L C P + W +N L +SER+ +
Sbjct: 240 LPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVL 299
Query: 310 SARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSY 369
A GS L I+DV +D G Y C+ADN E++ + P P A S
Sbjct: 300 LAGGS---LEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESM 356
Query: 370 TLSF 373
+ F
Sbjct: 357 DIVF 360
Score = 72.5 bits (170), Expect = 3e-12
Identities = 70/276 (25%), Positives = 108/276 (39%), Gaps = 27/276 (9%)
Query: 189 GGAAVLECRAAGNPVPTVTWHRLND-----SSSRLG--EGPQLQLSRLERHHGGVYACTV 241
G VL C A+G P PT+ W + + SS RL G L++S + G Y C
Sbjct: 263 GQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIA 322
Query: 242 DNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL 301
DNG + + +L V PE + + ++ E C V P V W +N +
Sbjct: 323 DNG-NETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMV 381
Query: 302 SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE-VSGRPGPARFTSP 360
S+ + H L + + D G Y C+A+N +G A+ + + PA T+
Sbjct: 382 IPSDYFKIV---KEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPA--TTG 436
Query: 361 PLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAAPAAKGSLTHR 420
PL AP S + ++L +R A + + V
Sbjct: 437 PLPSAPRDVVASLVSTRF-----IKLTWRTPASDP--HGDNLTYSVFYTKEGIARERVEN 489
Query: 421 VSH------ELRGLQPAAVYEAIVQAKNRYGWNEVS 450
SH ++ L PA VY V A+N++G E S
Sbjct: 490 TSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESS 525
Score = 44.8 bits (101), Expect = 7e-04
Identities = 44/163 (26%), Positives = 65/163 (39%), Gaps = 16/163 (9%)
Query: 188 RGGAAVLECRAAGNPVPTVTWHR-------LNDSSSRLGEGPQLQLSRL--ERHH---GG 235
RG + +L C A P P + W + ++D +L L +S + +H+ G
Sbjct: 66 RGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEG 125
Query: 236 VYACTVD-NGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSW 294
Y C +G + +L V P T + G A L C V AD V W
Sbjct: 126 YYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRW 185
Query: 295 YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADN 337
QN PL +RV G L+I++ D G Y CV ++
Sbjct: 186 EQNRQPLLLDDRVIKLPSG---MLVISNATEGDGGLYRCVVES 225
Score = 43.6 bits (98), Expect = 0.002
Identities = 32/109 (29%), Positives = 46/109 (42%), Gaps = 14/109 (12%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPE----TRHVTARRGGAAVLECRAAGNP 202
DAG Y C +A + T+E +V+A PE ++ A V EC G P
Sbjct: 314 DAGTYFC-----IADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKP 368
Query: 203 VPTVTWHRLND-----SSSRLGEGPQLQLSRLERHHGGVYACTVDNGVG 246
PTV W + D ++ + LQ+ L + G Y C +N VG
Sbjct: 369 TPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVG 417
>BC047244-1|AAH47244.1| 858|Homo sapiens neural cell adhesion
molecule 1 protein.
Length = 858
Score = 73.3 bits (172), Expect = 2e-12
Identities = 82/340 (24%), Positives = 138/340 (40%), Gaps = 44/340 (12%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D +Y+C I++ A +Q T+ + V + + L C A+G+P+P++
Sbjct: 281 DEAEYIC-IAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSI 339
Query: 207 TWHRL--NDSSSRLGEGPQ---------------------LQLSRLERHHGGVYACTVDN 243
TW N SS + L L ++ G Y CT N
Sbjct: 340 TWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASN 399
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS--FPL 301
+G + + L+V Y P++ + V+T EG + + C V A P A +SW+++ P
Sbjct: 400 TIGQDSQSMY-LEVQYAPKLQGPVA-VYTWEGNQVNITCEVFAYPSATISWFRDGQLLPS 457
Query: 302 SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPP 361
S + + S L + DFGNY+C A N +G+ + P +SP
Sbjct: 458 SNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTP---SSPS 514
Query: 362 LARA-PHSYTLSFAVDSYPPLDELRLL-YRQ--LAINESFQQPGRWHDVVLAAPAAKGSL 417
+ + P+S T D + +L Y+ A+ E +W+D A + +G +
Sbjct: 515 IDQVEPYSSTAQVQFDEPEATGGVPILKYKAEWRAVGEEVWH-SKWYDAKEA--SMEGIV 571
Query: 418 THRVSHELRGLQPAAVYEAIVQAKNRYGWNEVSDIFQFHT 457
T + GL+P Y + A N G E+S +F T
Sbjct: 572 T------IVGLKPETTYAVRLAALNGKGLGEISAASEFKT 605
Score = 62.5 bits (145), Expect = 3e-09
Identities = 52/223 (23%), Positives = 93/223 (41%), Gaps = 30/223 (13%)
Query: 147 DAGDYVCQISDRVARDQVH----TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNP 202
D G Y C+ +AR +++ V V VPP+++A + TA G + L C A G P
Sbjct: 183 DEGTYRCE-GRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFP 241
Query: 203 VPTVTWHRLNDSSSR---------LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
PT++W + + + + QL + +++++ Y C +N G T
Sbjct: 242 EPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDAT-I 300
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
L+V P+IT + + L C DP ++W ++ +S+ E+ + +
Sbjct: 301 HLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKASWTRPE 360
Query: 314 SNHT---------------LLIADVQPEDFGNYSCVADNSLGR 341
T L + +Q D G Y C A N++G+
Sbjct: 361 KQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQ 403
Score = 46.8 bits (106), Expect = 2e-04
Identities = 52/227 (22%), Positives = 83/227 (36%), Gaps = 13/227 (5%)
Query: 139 TNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRA 198
T + DAG Y C ++ + TV V + + R G AV+ C
Sbjct: 82 TIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDV 141
Query: 199 AGNPVPTVTW-HRLNDSSSRLG------EGPQLQLSRLERHHGGVYACTVDN-GVGPPVV 250
+ PT+ W H+ D + LQ+ +++ G Y C G
Sbjct: 142 VSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINF 201
Query: 251 TEFQLQVLYPPEITVERSWVHTGE--GFRAELVCTVLADPPAEVSWYQNSFPLSASERVT 308
+ Q+ V PP I ++ V+ G LVC P +SW ++ + E
Sbjct: 202 KDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDE 261
Query: 309 MSARGSNHT-LLIADVQPEDFGNYSCVADNSLGR--ARRHVEVSGRP 352
+ + L I V D Y C+A+N G A H++V +P
Sbjct: 262 KYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKP 308
Score = 33.9 bits (74), Expect = 1.3
Identities = 30/134 (22%), Positives = 56/134 (41%), Gaps = 14/134 (10%)
Query: 145 FQDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
+ DAG+Y+C S+ + +D Q +EV P ++ V G + C P
Sbjct: 387 YTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVA---VYTWEGNQVNITCEVFAYPS 443
Query: 204 PTVTWHR-------LNDSSSRLGEGPQ---LQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
T++W R N S+ ++ P L+++ + G Y CT N +G +
Sbjct: 444 ATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFI 503
Query: 254 QLQVLYPPEITVER 267
+Q P ++++
Sbjct: 504 LVQADTPSSPSIDQ 517
>BC014205-1|AAH14205.2| 601|Homo sapiens NCAM1 protein protein.
Length = 601
Score = 73.3 bits (172), Expect = 2e-12
Identities = 82/340 (24%), Positives = 138/340 (40%), Gaps = 44/340 (12%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D +Y+C I++ A +Q T+ + V + + L C A+G+P+P++
Sbjct: 24 DEAEYIC-IAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSI 82
Query: 207 TWHRL--NDSSSRLGEGPQ---------------------LQLSRLERHHGGVYACTVDN 243
TW N SS + L L ++ G Y CT N
Sbjct: 83 TWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASN 142
Query: 244 GVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS--FPL 301
+G + + L+V Y P++ + V+T EG + + C V A P A +SW+++ P
Sbjct: 143 TIGQDSQSMY-LEVQYAPKLQGPVA-VYTWEGNQVNITCEVFAYPSATISWFRDGQLLPS 200
Query: 302 SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPP 361
S + + S L + DFGNY+C A N +G+ + P +SP
Sbjct: 201 SNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTP---SSPS 257
Query: 362 LARA-PHSYTLSFAVDSYPPLDELRLL-YRQ--LAINESFQQPGRWHDVVLAAPAAKGSL 417
+ + P+S T D + +L Y+ A+ E +W+D A + +G +
Sbjct: 258 IDQVEPYSSTAQVQFDEPEATGGVPILKYKAEWRAVGEEVWH-SKWYDAKEA--SMEGIV 314
Query: 418 THRVSHELRGLQPAAVYEAIVQAKNRYGWNEVSDIFQFHT 457
T + GL+P Y + A N G E+S +F T
Sbjct: 315 T------IVGLKPETTYAVRLAALNGKGLGEISAASEFKT 348
Score = 40.7 bits (91), Expect = 0.012
Identities = 29/137 (21%), Positives = 55/137 (40%), Gaps = 16/137 (11%)
Query: 220 EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAE 279
+ QL + +++++ Y C +N G T L+V P+IT + +
Sbjct: 11 DSSQLTIKKVDKNDEAEYICIAENKAGEQDAT-IHLKVFAKPKITYVENQTAMELEEQVT 69
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT---------------LLIADVQ 324
L C DP ++W ++ +S+ E+ + + T L + +Q
Sbjct: 70 LTCEASGDPIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQ 129
Query: 325 PEDFGNYSCVADNSLGR 341
D G Y C A N++G+
Sbjct: 130 YTDAGEYICTASNTIGQ 146
Score = 33.9 bits (74), Expect = 1.3
Identities = 30/134 (22%), Positives = 56/134 (41%), Gaps = 14/134 (10%)
Query: 145 FQDAGDYVCQISDRVARD-QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
+ DAG+Y+C S+ + +D Q +EV P ++ V G + C P
Sbjct: 130 YTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVA---VYTWEGNQVNITCEVFAYPS 186
Query: 204 PTVTWHR-------LNDSSSRLGEGPQ---LQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
T++W R N S+ ++ P L+++ + G Y CT N +G +
Sbjct: 187 ATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFI 246
Query: 254 QLQVLYPPEITVER 267
+Q P ++++
Sbjct: 247 LVQADTPSSPSIDQ 260
>AY358125-1|AAQ88492.1| 937|Homo sapiens MAM-domain protein
protein.
Length = 937
Score = 73.3 bits (172), Expect = 2e-12
Identities = 48/170 (28%), Positives = 76/170 (44%), Gaps = 16/170 (9%)
Query: 182 RHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGP----QLQLSRLERHHGGVY 237
R T R G L C G+P P +S R + L+++ ++RH GG Y
Sbjct: 30 RVYTIREGETLELTCLVTGHPRPXRWTKTAGSASDRFQDSSVFNETLRITNIQRHQGGRY 89
Query: 238 ACTVDNGVGPPVVTEFQLQVLY--PPEITVERSWVHTGEGFRAE----LVCTVLADPPAE 291
C +NG+G P + ++ V Y P +TV +S E F E L C ++PP
Sbjct: 90 YCKAENGLGSPAIKSIRVDVYYLDDPVVTVHQSIGEAKEQFYYERTVFLRCVANSNPPVR 149
Query: 292 VSWYQ-NSFPLSASER-----VTMSARGSNHTLLIADVQPEDFGNYSCVA 335
SW + L S++ +G L + +++P+D+ NYSC+A
Sbjct: 150 YSWRRGQEVLLQGSDKGVEIYEPFFTQGETKILKLKNLRPQDYANYSCIA 199
Score = 66.9 bits (156), Expect = 2e-10
Identities = 80/334 (23%), Positives = 132/334 (39%), Gaps = 32/334 (9%)
Query: 137 GNTNFRMI---FQDAGDYVCQISDRVARDQVHTVEV-----LVPPSVRASPETRHVTARR 188
G TN +I F D G Y C S + +++V VPP++ E + R
Sbjct: 379 GTTNLDIIDLKFTDFGTYTCVASLKGGGISDISIDVNISSSTVPPNLTVPQEKSPLVTRE 438
Query: 189 GGAAVLECRAAGNPVPTVTWHR------LNDSSSRL-GEGPQLQLSRLERHHGGVYACTV 241
G L+C+ G P P + W R + D S ++ L++ + R G+Y C
Sbjct: 439 GDTIELQCQVTGKPKPIILWSRADKEVAMPDGSMQMESYDGTLRIVNVSREMSGMYRCQT 498
Query: 242 D--NGVG-PPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS 298
NG P QL V YPP + + G+ + C VL P V Y+
Sbjct: 499 SQYNGFNVKPREALVQLIVQYPPAVEPAFLEIRQGQNRSVTMSCRVLRAYPIRVLTYE-- 556
Query: 299 FPLSASERVTMSARGSNHT-LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF 357
+ L T +T + + E++G Y+C N G R V+G+ F
Sbjct: 557 WRLGNKLLRTGQFDSQEYTEYAVKSLSNENYGVYNCSIINEAGAGRCSFLVTGKAYAPEF 616
Query: 358 ---TSPPLARAPH---SYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAAP 411
T P+ + H SY+L + + +D R++ +L I ++ QQ ++ +
Sbjct: 617 YYDTYNPVWQNRHRVYSYSLQWTQMNPDAVD--RIVAYRLGIRQAGQQRWWEQEIKINGN 674
Query: 412 AAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYG 445
KG L +++ L L YE + ++G
Sbjct: 675 IQKGEL---ITYNLTELIKPEAYEVRLTPLTKFG 705
Score = 59.3 bits (137), Expect = 3e-08
Identities = 57/228 (25%), Positives = 91/228 (39%), Gaps = 22/228 (9%)
Query: 152 VCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLEC-RAAGNPVPTVTWHR 210
VC I D++ ++ PS++ + + G A L C G P P++TW R
Sbjct: 204 VCNIPDKMVSFRLSNKTA--SPSIKLLVDDP-IVVNPGEAITLVCVTTGGEPAPSLTWVR 260
Query: 211 LNDS--SSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVV--TEFQLQVLYPPEITVE 266
+ + G L + + G Y+C +N VG P T ++ L +
Sbjct: 261 SFGTLPEKTVLNGGTLTIPAITSDDAGTYSCIANNNVGNPAKKSTNIIVRALKKGRFWIT 320
Query: 267 RSWVHTGE----GFRAELVCTVLADPPAEV--SWYQNSFPLSASERVTMS-----ARGSN 315
H + G ++ C V A P E+ SW++N PL +SER+ ++
Sbjct: 321 PDPYHKDDNIQIGREVKISCQVEAVPSEELTFSWFKNGRPLRSSERMVITQTDPDVSPGT 380
Query: 316 HTLLIADVQPEDFGNYSCVAD---NSLGRARRHVEVSGRPGPARFTSP 360
L I D++ DFG Y+CVA + V +S P T P
Sbjct: 381 TNLDIIDLKFTDFGTYTCVASLKGGGISDISIDVNISSSTVPPNLTVP 428
Score = 34.7 bits (76), Expect = 0.76
Identities = 25/67 (37%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
EG EL C V P W + + SAS+R S+ N TL I ++Q G Y C
Sbjct: 36 EGETLELTCLVTGHP-RPXRWTKTAG--SASDRFQDSSV-FNETLRITNIQRHQGGRYYC 91
Query: 334 VADNSLG 340
A+N LG
Sbjct: 92 KAENGLG 98
>AF190637-1|AAG17141.1| 1241|Homo sapiens nephrin protein.
Length = 1241
Score = 73.3 bits (172), Expect = 2e-12
Identities = 87/323 (26%), Positives = 138/323 (42%), Gaps = 41/323 (12%)
Query: 153 CQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV-PTV-TWHR 210
CQ S+ A ++ ++V P++RA + V GG+ + C NP+ P + W R
Sbjct: 721 CQNSEGTAEARLR-LDVHYAPTIRALQDPTEVNV--GGSVDIVCTVDANPILPGMFNWER 777
Query: 211 LN--------DSSSRLGEGP--QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
L D ++ GP +L++ + G Y C VDNGV PP +L V +
Sbjct: 778 LGEDEEDQSLDDMEKISRGPTGRLRIHHAKLAQAGAYQCIVDNGVAPPARRLLRLVVRFA 837
Query: 261 PEI---TVERSWVHTGEG-FRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSA--RG 313
P++ T G+ A L C P +W +N PL + R T +G
Sbjct: 838 PQVEHPTPLTKVAAAGDSTSSATLHCRARGVPNIVFTWTKNGVPLDLQDPRYTEHTYHQG 897
Query: 314 SNHT--LLIADVQ-PEDFGNYSCVADNSLGRARRHVEV--SGRPGPARFTSPPLARAPHS 368
H+ L IA+V +D+ ++C A N+LG + ++++ RP P ++ PHS
Sbjct: 898 GVHSSLLTIANVSAAQDYALFTCTATNALGSDQTNIQLVSISRPDPPSGLK-VVSLTPHS 956
Query: 369 YTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGL 428
L + P D L R E+ PG +H V + P A + L GL
Sbjct: 957 VGLEWK----PGFDG-GLPQRFCIRYEALGTPG-FHYVDVVPPQA-------TTFTLTGL 1003
Query: 429 QPAAVYEAIVQAKNRYGWNEVSD 451
QP+ Y + A N G + ++D
Sbjct: 1004 QPSTRYRVWLLASNALGDSGLAD 1026
>AF035835-1|AAC39687.1| 1241|Homo sapiens nephrin protein.
Length = 1241
Score = 73.3 bits (172), Expect = 2e-12
Identities = 87/323 (26%), Positives = 138/323 (42%), Gaps = 41/323 (12%)
Query: 153 CQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV-PTV-TWHR 210
CQ S+ A ++ ++V P++RA + V GG+ + C NP+ P + W R
Sbjct: 721 CQNSEGTAEARLR-LDVHYAPTIRALQDPTEVNV--GGSVDIVCTVDANPILPGMFNWER 777
Query: 211 LN--------DSSSRLGEGP--QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
L D ++ GP +L++ + G Y C VDNGV PP +L V +
Sbjct: 778 LGEDEEDQSLDDMEKISRGPTGRLRIHHAKLAQAGAYQCIVDNGVAPPARRLLRLVVRFA 837
Query: 261 PEI---TVERSWVHTGEG-FRAELVCTVLADPPAEVSWYQNSFPLSASE-RVTMSA--RG 313
P++ T G+ A L C P +W +N PL + R T +G
Sbjct: 838 PQVEHPTPLTKVAAAGDSTSSATLHCRARGVPNIVFTWTKNGVPLDLQDPRYTEHTYHQG 897
Query: 314 SNHT--LLIADVQ-PEDFGNYSCVADNSLGRARRHVEV--SGRPGPARFTSPPLARAPHS 368
H+ L IA+V +D+ ++C A N+LG + ++++ RP P ++ PHS
Sbjct: 898 GVHSSLLTIANVSAAQDYALFTCTATNALGSDQTNIQLVSISRPDPPSGLK-VVSLTPHS 956
Query: 369 YTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGL 428
L + P D L R E+ PG +H V + P A + L GL
Sbjct: 957 VGLEWK----PGFDG-GLPQRFCIRYEALGTPG-FHYVDVVPPQA-------TTFTLTGL 1003
Query: 429 QPAAVYEAIVQAKNRYGWNEVSD 451
QP+ Y + A N G + ++D
Sbjct: 1004 QPSTRYRVWLLASNALGDSGLAD 1026
>X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein.
Length = 1447
Score = 72.9 bits (171), Expect = 2e-12
Identities = 82/279 (29%), Positives = 113/279 (40%), Gaps = 23/279 (8%)
Query: 183 HVTARRGGAAVLECRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGV 236
+V A G AVLEC +G P P+ TW R L L G L +S + G+
Sbjct: 248 NVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGM 307
Query: 237 YACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ 296
Y C V + +L VL PP S ++ E E CTV P V+W +
Sbjct: 308 YTCVVTYK-NENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMK 366
Query: 297 NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPAR 356
N + S+ + GSN L I V D G Y CVA+N G A+ ++ P PA
Sbjct: 367 NGDVVIPSDYFQI-VGGSN--LRILGVVKSDEGFYQCVAENEAGNAQTSAQLI-VPKPAI 422
Query: 357 FTSPPLARAPHS-----YTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAAP 411
+S L AP + F S+ P E + + + S + R + P
Sbjct: 423 PSSSVLPSAPRDVVPVLVSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDNRERALNTTQP 482
Query: 412 AAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
GSL V + L+P A+Y V A N +G E S
Sbjct: 483 ---GSLQLTVGN----LKPEAMYTFRVVAYNEWGPGESS 514
Score = 71.3 bits (167), Expect = 7e-12
Identities = 60/203 (29%), Positives = 91/203 (44%), Gaps = 17/203 (8%)
Query: 147 DAGDYVCQISDRVARDQV-HTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C+ S + + T +V V +R +T VTA G +L+C G P+PT
Sbjct: 111 DEGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPT 170
Query: 206 VTWHRLND------SSSRLGEGPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W + SR+ P LQ+SRL+ G+Y C+ N E ++++
Sbjct: 171 IHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRI 230
Query: 258 LYPPEI-----TVER-SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA 311
L P + ++R S V EG A L C V PP +W + + +
Sbjct: 231 LSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLL 290
Query: 312 RGSNHTLLIADVQPEDFGNYSCV 334
GSN LLI++V +D G Y+CV
Sbjct: 291 GGSN--LLISNVTDDDSGMYTCV 311
Score = 50.4 bits (115), Expect = 1e-05
Identities = 48/192 (25%), Positives = 78/192 (40%), Gaps = 20/192 (10%)
Query: 163 QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNP-VPTVTWHR--------LND 213
QV ++ ++R E RGG +L+C A + VP + W + +++
Sbjct: 28 QVTGFQIKAFTALRFLSEPSDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDE 87
Query: 214 SSSRLGEGPQLQLSRLE-RHHG---GVYACTVDNGVGPPVVTEF-QLQVLYPPEITVERS 268
+L G L + L RHH G+Y C G +++ ++ V P +
Sbjct: 88 RKQQLSNGSLLIQNILHSRHHKPDEGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTE 147
Query: 269 WVHTGEGFRAELVCTVLADPPAEVSWYQNS---FPLSASERVTMSARGSNHTLLIADVQP 325
V G L C V+ +P + W +N P+ RV + G+ L I+ +QP
Sbjct: 148 SVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGA---LQISRLQP 204
Query: 326 EDFGNYSCVADN 337
D G Y C A N
Sbjct: 205 GDIGIYRCSARN 216
Score = 31.5 bits (68), Expect = 7.1
Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 5/71 (7%)
Query: 24 GP-RFLSRGHSFRTVVGDTLLLPCQVQNLGSLVLLWRRAPAVLTAASLMVTRDERFRLVD 82
GP RFLS+ S +GDT+LL C+V + W++ LT + D R ++
Sbjct: 138 GPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTP----IPGDSRVVVLP 193
Query: 83 GYNLQITDVGP 93
LQI+ + P
Sbjct: 194 SGALQISRLQP 204
>M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorectal
tumor suppressor mRNA (DCC), 5' end. ).
Length = 750
Score = 72.9 bits (171), Expect = 2e-12
Identities = 82/279 (29%), Positives = 113/279 (40%), Gaps = 23/279 (8%)
Query: 183 HVTARRGGAAVLECRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGV 236
+V A G AVLEC +G P P+ TW R L L G L +S + G+
Sbjct: 248 NVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGM 307
Query: 237 YACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ 296
Y C V + +L VL PP S ++ E E CTV P V+W +
Sbjct: 308 YTCVVTYK-NENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMK 366
Query: 297 NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPAR 356
N + S+ + GSN L I V D G Y CVA+N G A+ ++ P PA
Sbjct: 367 NGDVVIPSDYFQI-VGGSN--LRILGVVKSDEGFYQCVAENEAGNAQTSAQLI-VPKPAI 422
Query: 357 FTSPPLARAPHS-----YTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAAP 411
+S L AP + F S+ P E + + + S + R + P
Sbjct: 423 PSSSVLPSAPRDVVPVLVSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDNRERALNTTQP 482
Query: 412 AAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
GSL V + L+P A+Y V A N +G E S
Sbjct: 483 ---GSLQLTVGN----LKPEAMYTFRVVAYNEWGPGESS 514
Score = 71.3 bits (167), Expect = 7e-12
Identities = 60/203 (29%), Positives = 91/203 (44%), Gaps = 17/203 (8%)
Query: 147 DAGDYVCQISDRVARDQV-HTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C+ S + + T +V V +R +T VTA G +L+C G P+PT
Sbjct: 111 DEGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPT 170
Query: 206 VTWHRLND------SSSRLGEGPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W + SR+ P LQ+SRL+ G+Y C+ N E ++++
Sbjct: 171 IHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRI 230
Query: 258 LYPPEI-----TVER-SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA 311
L P + ++R S V EG A L C V PP +W + + +
Sbjct: 231 LSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLL 290
Query: 312 RGSNHTLLIADVQPEDFGNYSCV 334
GSN LLI++V +D G Y+CV
Sbjct: 291 GGSN--LLISNVTDDDSGMYTCV 311
Score = 50.4 bits (115), Expect = 1e-05
Identities = 48/192 (25%), Positives = 78/192 (40%), Gaps = 20/192 (10%)
Query: 163 QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNP-VPTVTWHR--------LND 213
QV ++ ++R E RGG +L+C A + VP + W + +++
Sbjct: 28 QVTGFQIKAFTALRFLSEPSDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDE 87
Query: 214 SSSRLGEGPQLQLSRLE-RHHG---GVYACTVDNGVGPPVVTEF-QLQVLYPPEITVERS 268
+L G L + L RHH G+Y C G +++ ++ V P +
Sbjct: 88 RKQQLSNGSLLIQNILHSRHHKPDEGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTE 147
Query: 269 WVHTGEGFRAELVCTVLADPPAEVSWYQNS---FPLSASERVTMSARGSNHTLLIADVQP 325
V G L C V+ +P + W +N P+ RV + G+ L I+ +QP
Sbjct: 148 SVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGA---LQISRLQP 204
Query: 326 EDFGNYSCVADN 337
D G Y C A N
Sbjct: 205 GDIGIYRCSARN 216
Score = 31.5 bits (68), Expect = 7.1
Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 5/71 (7%)
Query: 24 GP-RFLSRGHSFRTVVGDTLLLPCQVQNLGSLVLLWRRAPAVLTAASLMVTRDERFRLVD 82
GP RFLS+ S +GDT+LL C+V + W++ LT + D R ++
Sbjct: 138 GPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTP----IPGDSRVVVLP 193
Query: 83 GYNLQITDVGP 93
LQI+ + P
Sbjct: 194 SGALQISRLQP 204
>AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein.
Length = 1026
Score = 72.5 bits (170), Expect = 3e-12
Identities = 63/243 (25%), Positives = 97/243 (39%), Gaps = 25/243 (10%)
Query: 125 WETTRRITSEQHGNTNFRMIFQ-DAGDYVCQISDRVARDQV---HTVEVL--------VP 172
++ RR S++ GN + + D G+Y C +++ V +V T +L
Sbjct: 165 YQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYE 224
Query: 173 PSVRAS-PETRHVTARRGGAAVLECRAAGNPVPTVTWHRLND-----SSSRLGEGPQLQL 226
P + PET V +G LEC A GNPVPT+ W R + + R L++
Sbjct: 225 PKIEVQFPET--VPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARRHKSNGILEI 282
Query: 227 SRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLA 286
++ G+Y C +N G V QL P + + +H C
Sbjct: 283 PNFQQEDAGLYECVAENSRGKN-VARGQLTFYAQPNWIQKINDIHVAMEENVFWECKANG 341
Query: 287 DPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
P W +N PL +R+ + TL I V D G Y C+A+N G +
Sbjct: 342 RPKPTYKWLKNGEPLLTRDRIQI----EQGTLNITIVNLSDAGMYQCLAENKHGVIFSNA 397
Query: 347 EVS 349
E+S
Sbjct: 398 ELS 400
Score = 61.7 bits (143), Expect = 6e-09
Identities = 63/244 (25%), Positives = 94/244 (38%), Gaps = 18/244 (7%)
Query: 127 TTRRITSEQHGNTNFRMI-FQDAGDYVCQISDR--VARDQVHTVEVLVPPSVRASPETRH 183
T RI EQ G N ++ DAG Y C ++ V + V P + R
Sbjct: 358 TRDRIQIEQ-GTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVIAVGPDFSRTLLKRV 416
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLND---SSSR--LGEGPQLQLSRLERHHGGVYA 238
+ GG V+EC+ +P P TW + D + R + E L++ + + G Y
Sbjct: 417 TLVKVGGEVVIECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDAGSYT 476
Query: 239 CTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEV--SWYQ 296
C N G T L V P + V S + G L C V D ++ +W
Sbjct: 477 CIATNHFGTASSTG-NLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSF 535
Query: 297 N----SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGR--ARRHVEVSG 350
N F + + S L+I ++Q + G Y C+ S+ R A + V G
Sbjct: 536 NGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRG 595
Query: 351 RPGP 354
PGP
Sbjct: 596 PPGP 599
Score = 59.3 bits (137), Expect = 3e-08
Identities = 52/159 (32%), Positives = 66/159 (41%), Gaps = 19/159 (11%)
Query: 194 LECRAAGNPVPTVTWHRLNDSSSRLG--------EGPQLQLSRLERHHGGVYACTVDNGV 245
L C GNP P + W +LN + G EG L + + G Y CT N
Sbjct: 48 LNCEVKGNPKPHIRW-KLNGTDVDTGMDFRYSVVEGSLLINNPNKTQDAGTYQCTATNSF 106
Query: 246 GPPVVTEFQLQVLYPPEI-TVERSWVHTGEGFRAELVCTVLADPP--AEVS--WYQNSFP 300
G V E +LQ Y T RS V G L+C PP E+S W N +P
Sbjct: 107 GTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQGMVLLC---GPPPHSGELSYAWIFNEYP 163
Query: 301 LSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
R +S N L IA V+ D GNY+CV N++
Sbjct: 164 SYQDNRRFVSQETGN--LYIAKVEKSDVGNYTCVVTNTV 200
>AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein.
Length = 1026
Score = 72.5 bits (170), Expect = 3e-12
Identities = 63/243 (25%), Positives = 97/243 (39%), Gaps = 25/243 (10%)
Query: 125 WETTRRITSEQHGNTNFRMIFQ-DAGDYVCQISDRVARDQV---HTVEVL--------VP 172
++ RR S++ GN + + D G+Y C +++ V +V T +L
Sbjct: 165 YQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYE 224
Query: 173 PSVRAS-PETRHVTARRGGAAVLECRAAGNPVPTVTWHRLND-----SSSRLGEGPQLQL 226
P + PET V +G LEC A GNPVPT+ W R + + R L++
Sbjct: 225 PKIEVQFPET--VPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARRHKSNGILEI 282
Query: 227 SRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLA 286
++ G+Y C +N G V QL P + + +H C
Sbjct: 283 PNFQQEDAGLYECVAENSRGKN-VARGQLTFYAQPNWIQKINDIHVAMEENVFWECKANG 341
Query: 287 DPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
P W +N PL +R+ + TL I V D G Y C+A+N G +
Sbjct: 342 RPKPTYKWLKNGEPLLTRDRIQI----EQGTLNITIVNLSDAGMYQCLAENKHGVIFSNA 397
Query: 347 EVS 349
E+S
Sbjct: 398 ELS 400
Score = 61.7 bits (143), Expect = 6e-09
Identities = 63/244 (25%), Positives = 94/244 (38%), Gaps = 18/244 (7%)
Query: 127 TTRRITSEQHGNTNFRMI-FQDAGDYVCQISDR--VARDQVHTVEVLVPPSVRASPETRH 183
T RI EQ G N ++ DAG Y C ++ V + V P + R
Sbjct: 358 TRDRIQIEQ-GTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVIAVGPDFSRTLLKRV 416
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLND---SSSR--LGEGPQLQLSRLERHHGGVYA 238
+ GG V+EC+ +P P TW + D + R + E L++ + + G Y
Sbjct: 417 TLVKVGGEVVIECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDAGSYT 476
Query: 239 CTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEV--SWYQ 296
C N G T L V P + V S + G L C V D ++ +W
Sbjct: 477 CIATNHFGTASSTG-NLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSF 535
Query: 297 N----SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGR--ARRHVEVSG 350
N F + + S L+I ++Q + G Y C+ S+ R A + V G
Sbjct: 536 NGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRG 595
Query: 351 RPGP 354
PGP
Sbjct: 596 PPGP 599
Score = 59.3 bits (137), Expect = 3e-08
Identities = 52/159 (32%), Positives = 66/159 (41%), Gaps = 19/159 (11%)
Query: 194 LECRAAGNPVPTVTWHRLNDSSSRLG--------EGPQLQLSRLERHHGGVYACTVDNGV 245
L C GNP P + W +LN + G EG L + + G Y CT N
Sbjct: 48 LNCEVKGNPKPHIRW-KLNGTDVDTGMDFRYSVVEGSLLINNPNKTQDAGTYQCTATNSF 106
Query: 246 GPPVVTEFQLQVLYPPEI-TVERSWVHTGEGFRAELVCTVLADPP--AEVS--WYQNSFP 300
G V E +LQ Y T RS V G L+C PP E+S W N +P
Sbjct: 107 GTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQGMVLLC---GPPPHSGELSYAWIFNEYP 163
Query: 301 LSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
R +S N L IA V+ D GNY+CV N++
Sbjct: 164 SYQDNRRFVSQETGN--LYIAKVEKSDVGNYTCVVTNTV 200
>BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein.
Length = 1192
Score = 71.3 bits (167), Expect = 7e-12
Identities = 57/235 (24%), Positives = 91/235 (38%), Gaps = 11/235 (4%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+G+Y C + + HT+ V V + +++ G L CRA GNP P +
Sbjct: 315 DSGNYQCIAKNALGAIH-HTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRI 373
Query: 207 TW-------HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+W D SR +G + S ++ VY C N G + F +
Sbjct: 374 SWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE 433
Query: 260 PPEITVERSWVHTGEGFRAELV-CTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP I + ++ R L+ C P + W++ + + E + + N TL
Sbjct: 434 PPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE--NGTL 491
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTLSF 373
I Q + G Y+CVA N LG A+ V + + P A +SF
Sbjct: 492 EIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYAVVQRGSMVSF 546
Score = 63.3 bits (147), Expect = 2e-09
Identities = 64/256 (25%), Positives = 107/256 (41%), Gaps = 25/256 (9%)
Query: 167 VEVLV-PPSVRASPETRH-VTARRGGAAVLECRAAGNPVPTVTWHR------LNDSSSRL 218
V VL PP + T + V A R A+L+C G+P+PT+ W + L++ L
Sbjct: 428 VNVLAEPPRILTPANTLYQVIANR--PALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVL 485
Query: 219 GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRA 278
E L++ ++ G Y C N +G E L++ I + + G
Sbjct: 486 HENGTLEIPVAQKDSTGTYTCVARNKLGM-AKNEVHLEIKDATWIVKQPEYAVVQRGSMV 544
Query: 279 ELVCTVLADPPAEVS--WYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVAD 336
C V D ++ W +++ L + ER T+ +H L++ADV +D G Y+CVA+
Sbjct: 545 SFECKVKHDHTLSLTVLWLKDNRELPSDERFTVD---KDH-LVVADVSDDDSGTYTCVAN 600
Query: 337 NSLGRARRHVEVS-GRPGPARFTSPPLARAPHSYTLSFAVD-----SYPPLDELRLLYRQ 390
+L +S P P + P L+ +D S+ P D+ +
Sbjct: 601 TTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITK 660
Query: 391 LAI--NESFQQPGRWH 404
I ++ +PG WH
Sbjct: 661 FIIEYEDAMHKPGLWH 676
Score = 52.0 bits (119), Expect = 5e-06
Identities = 56/252 (22%), Positives = 94/252 (37%), Gaps = 21/252 (8%)
Query: 128 TRRITSEQHGNTNFRMIFQD--AGDYVCQI----SDRVARDQVHTVEVLVPPSVRASPET 181
+ R++ +G+ F + + DY+C + + + Q +V+V+ S R P T
Sbjct: 191 SERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISAKSSRERPPT 250
Query: 182 --------RHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSR 228
+ RG LEC A G P P + W + + + + LQ+
Sbjct: 251 FLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIH 310
Query: 229 LERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADP 288
+ G Y C N +G T P IT ++ V G L+C +P
Sbjct: 311 VSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLV-LSPGEDGTLICRANGNP 369
Query: 289 PAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
+SW N P+ + S + T++ ++VQ Y C A N G + V
Sbjct: 370 KPRISWLTNGVPIEIAPD-DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFV 428
Query: 349 SGRPGPARFTSP 360
+ P R +P
Sbjct: 429 NVLAEPPRILTP 440
>BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein.
Length = 1180
Score = 71.3 bits (167), Expect = 7e-12
Identities = 57/235 (24%), Positives = 91/235 (38%), Gaps = 11/235 (4%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+G+Y C + + HT+ V V + +++ G L CRA GNP P +
Sbjct: 315 DSGNYQCIAKNALGAIH-HTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRI 373
Query: 207 TW-------HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+W D SR +G + S ++ VY C N G + F +
Sbjct: 374 SWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE 433
Query: 260 PPEITVERSWVHTGEGFRAELV-CTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP I + ++ R L+ C P + W++ + + E + + N TL
Sbjct: 434 PPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE--NGTL 491
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTLSF 373
I Q + G Y+CVA N LG A+ V + + P A +SF
Sbjct: 492 EIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYAVVQRGSMVSF 546
Score = 63.3 bits (147), Expect = 2e-09
Identities = 64/256 (25%), Positives = 107/256 (41%), Gaps = 25/256 (9%)
Query: 167 VEVLV-PPSVRASPETRH-VTARRGGAAVLECRAAGNPVPTVTWHR------LNDSSSRL 218
V VL PP + T + V A R A+L+C G+P+PT+ W + L++ L
Sbjct: 428 VNVLAEPPRILTPANTLYQVIANR--PALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVL 485
Query: 219 GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRA 278
E L++ ++ G Y C N +G E L++ I + + G
Sbjct: 486 HENGTLEIPVAQKDSTGTYTCVARNKLGM-AKNEVHLEIKDATWIVKQPEYAVVQRGSMV 544
Query: 279 ELVCTVLADPPAEVS--WYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVAD 336
C V D ++ W +++ L + ER T+ +H L++ADV +D G Y+CVA+
Sbjct: 545 SFECKVKHDHTLSLTVLWLKDNRELPSDERFTVD---KDH-LVVADVSDDDSGTYTCVAN 600
Query: 337 NSLGRARRHVEVS-GRPGPARFTSPPLARAPHSYTLSFAVD-----SYPPLDELRLLYRQ 390
+L +S P P + P L+ +D S+ P D+ +
Sbjct: 601 TTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITK 660
Query: 391 LAI--NESFQQPGRWH 404
I ++ +PG WH
Sbjct: 661 FIIEYEDAMHKPGLWH 676
Score = 52.0 bits (119), Expect = 5e-06
Identities = 56/252 (22%), Positives = 94/252 (37%), Gaps = 21/252 (8%)
Query: 128 TRRITSEQHGNTNFRMIFQD--AGDYVCQI----SDRVARDQVHTVEVLVPPSVRASPET 181
+ R++ +G+ F + + DY+C + + + Q +V+V+ S R P T
Sbjct: 191 SERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISAKSSRERPPT 250
Query: 182 --------RHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSR 228
+ RG LEC A G P P + W + + + + LQ+
Sbjct: 251 FLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIH 310
Query: 229 LERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADP 288
+ G Y C N +G T P IT ++ V G L+C +P
Sbjct: 311 VSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLV-LSPGEDGTLICRANGNP 369
Query: 289 PAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
+SW N P+ + S + T++ ++VQ Y C A N G + V
Sbjct: 370 KPRISWLTNGVPIEIAPD-DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFV 428
Query: 349 SGRPGPARFTSP 360
+ P R +P
Sbjct: 429 NVLAEPPRILTP 440
>BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein.
Length = 771
Score = 71.3 bits (167), Expect = 7e-12
Identities = 57/235 (24%), Positives = 91/235 (38%), Gaps = 11/235 (4%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+G+Y C + + HT+ V V + +++ G L CRA GNP P +
Sbjct: 328 DSGNYQCIAKNALGAIH-HTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRI 386
Query: 207 TW-------HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+W D SR +G + S ++ VY C N G + F +
Sbjct: 387 SWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE 446
Query: 260 PPEITVERSWVHTGEGFRAELV-CTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP I + ++ R L+ C P + W++ + + E + + N TL
Sbjct: 447 PPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE--NGTL 504
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTLSF 373
I Q + G Y+CVA N LG A+ V + + P A +SF
Sbjct: 505 EIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYAVVQRGSMVSF 559
Score = 62.9 bits (146), Expect = 3e-09
Identities = 65/252 (25%), Positives = 108/252 (42%), Gaps = 27/252 (10%)
Query: 167 VEVLV-PPSVRASPETRH-VTARRGGAAVLECRAAGNPVPTVTWHR------LNDSSSRL 218
V VL PP + T + V A R A+L+C G+P+PT+ W + L++ L
Sbjct: 441 VNVLAEPPRILTPANTLYQVIANR--PALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVL 498
Query: 219 GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRA 278
E L++ ++ G Y C N +G E L++ I + + G
Sbjct: 499 HENGTLEIPVAQKDSTGTYTCVARNKLGM-AKNEVHLEIKDATWIVKQPEYAVVQRGSMV 557
Query: 279 ELVCTVLADPPAEVS--WYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVAD 336
C V D ++ W +++ L + ER T+ +H L++ADV +D G Y+CVA+
Sbjct: 558 SFECKVKHDHTLSLTVLWLKDNRELPSDERFTVD---KDH-LVVADVSDDDSGTYTCVAN 613
Query: 337 NSLG--RARRHVEVSGRPGPARFTSPPLARAPHSYTLSFAV--DSYPPLDELRLLYRQLA 392
+L A + V P P F + S LS+ D+ P+ + + Y
Sbjct: 614 TTLDSVSASAVLSVVDVPNPP-FDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEY---- 668
Query: 393 INESFQQPGRWH 404
++ +PG WH
Sbjct: 669 -EDAMHKPGLWH 679
Score = 50.8 bits (116), Expect = 1e-05
Identities = 43/178 (24%), Positives = 66/178 (37%), Gaps = 7/178 (3%)
Query: 188 RGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLERHHGGVYACTVD 242
RG LEC A G P P + W + + + + LQ+ + G Y C
Sbjct: 278 RGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAK 337
Query: 243 NGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLS 302
N +G T P IT ++ V G L+C +P +SW N P+
Sbjct: 338 NALGAIHHTISVRVKAAPYWITAPQNLV-LSPGEDGTLICRANGNPKPRISWLTNGVPIE 396
Query: 303 ASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
+ S + T++ ++VQ Y C A N G + V+ P R +P
Sbjct: 397 IAPD-DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTP 453
>AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein.
Length = 1187
Score = 71.3 bits (167), Expect = 7e-12
Identities = 57/235 (24%), Positives = 91/235 (38%), Gaps = 11/235 (4%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+G+Y C + + HT+ V V + +++ G L CRA GNP P +
Sbjct: 322 DSGNYQCIAKNALGAIH-HTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRI 380
Query: 207 TW-------HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+W D SR +G + S ++ VY C N G + F +
Sbjct: 381 SWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE 440
Query: 260 PPEITVERSWVHTGEGFRAELV-CTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP I + ++ R L+ C P + W++ + + E + + N TL
Sbjct: 441 PPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE--NGTL 498
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTLSF 373
I Q + G Y+CVA N LG A+ V + + P A +SF
Sbjct: 499 EIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYAVVQRGSMVSF 553
Score = 63.3 bits (147), Expect = 2e-09
Identities = 64/256 (25%), Positives = 107/256 (41%), Gaps = 25/256 (9%)
Query: 167 VEVLV-PPSVRASPETRH-VTARRGGAAVLECRAAGNPVPTVTWHR------LNDSSSRL 218
V VL PP + T + V A R A+L+C G+P+PT+ W + L++ L
Sbjct: 435 VNVLAEPPRILTPANTLYQVIANR--PALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVL 492
Query: 219 GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRA 278
E L++ ++ G Y C N +G E L++ I + + G
Sbjct: 493 HENGTLEIPVAQKDSTGTYTCVARNKLGM-AKNEVHLEIKDATWIVKQPEYAVVQRGSMV 551
Query: 279 ELVCTVLADPPAEVS--WYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVAD 336
C V D ++ W +++ L + ER T+ +H L++ADV +D G Y+CVA+
Sbjct: 552 SFECKVKHDHTLSLTVLWLKDNRELPSDERFTVD---KDH-LVVADVSDDDSGTYTCVAN 607
Query: 337 NSLGRARRHVEVS-GRPGPARFTSPPLARAPHSYTLSFAVD-----SYPPLDELRLLYRQ 390
+L +S P P + P L+ +D S+ P D+ +
Sbjct: 608 TTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITK 667
Query: 391 LAI--NESFQQPGRWH 404
I ++ +PG WH
Sbjct: 668 FIIEYEDAMHKPGLWH 683
Score = 52.0 bits (119), Expect = 5e-06
Identities = 56/252 (22%), Positives = 94/252 (37%), Gaps = 21/252 (8%)
Query: 128 TRRITSEQHGNTNFRMIFQD--AGDYVCQI----SDRVARDQVHTVEVLVPPSVRASPET 181
+ R++ +G+ F + + DY+C + + + Q +V+V+ S R P T
Sbjct: 198 SERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISAKSSRERPPT 257
Query: 182 --------RHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSR 228
+ RG LEC A G P P + W + + + + LQ+
Sbjct: 258 FLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIH 317
Query: 229 LERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADP 288
+ G Y C N +G T P IT ++ V G L+C +P
Sbjct: 318 VSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLV-LSPGEDGTLICRANGNP 376
Query: 289 PAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
+SW N P+ + S + T++ ++VQ Y C A N G + V
Sbjct: 377 KPRISWLTNGVPIEIAPD-DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFV 435
Query: 349 SGRPGPARFTSP 360
+ P R +P
Sbjct: 436 NVLAEPPRILTP 447
>X59350-1|CAA42006.1| 847|Homo sapiens B Cell membrane protein CD22
protein.
Length = 847
Score = 70.9 bits (166), Expect = 1e-11
Identities = 62/201 (30%), Positives = 86/201 (42%), Gaps = 21/201 (10%)
Query: 153 CQISDR----VARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECR-AAGNP-VPTV 206
CQ+ D ++ D V + V P + R G + + C ++ NP TV
Sbjct: 219 CQLQDADGKFLSNDTVQ-LNVKHTPKLEIKVTPSDAIVREGDSVTMTCEVSSSNPEYTTV 277
Query: 207 TWHRLNDSSSRLGEGP-QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE-IT 264
+W L D +S + L L + + G Y C V N VGP E LQV Y PE T
Sbjct: 278 SW--LKDGTSLKKQNTFTLNLREVTKDQSGKYCCQVSNDVGPGRSEEVFLQVQYAPEPST 335
Query: 265 VERSWVHTGEGFRAELVCTVLADP-PAEVSWYQNSFPLSASERVTMSARGSNHTLLIADV 323
V+ EG + E +C LA+P P +WY N M R + + I +
Sbjct: 336 VQILHSPAVEGSQVEFLCMSLANPLPTNYTWYHNG--------KEMQGR-TEEKVHIPKI 386
Query: 324 QPEDFGNYSCVADNSLGRARR 344
P G YSCVA+N LG +R
Sbjct: 387 LPWHAGTYSCVAENILGTGQR 407
Score = 52.4 bits (120), Expect = 4e-06
Identities = 44/153 (28%), Positives = 63/153 (41%), Gaps = 6/153 (3%)
Query: 125 WETTRRITSEQHGNTNFRMIF-QDAGDYVCQISDRVAR--DQVHTVEVLVPPSVRASPET 181
WE R+ ++ NF I +DAG Y C +++ + + + T+EVL P +
Sbjct: 543 WEKNGRLLGKE-SQLNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSMS 601
Query: 182 RHVTARRGGAAVLECRAAGNP-VPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACT 240
G +A L C + NP V TW N+ S +L+L ++ H G Y C
Sbjct: 602 PGDQVMEGKSATLTCESDANPPVSHYTWFDWNNQSLP-HHSQKLRLEPVKVQHSGAYWCQ 660
Query: 241 VDNGVGPPVVTEFQLQVLYPPEITVERSWVHTG 273
N VG L V Y PE R V G
Sbjct: 661 GTNSVGKGRSPLSTLTVYYSPETIGRRVAVGLG 693
Score = 45.2 bits (102), Expect = 5e-04
Identities = 36/129 (27%), Positives = 55/129 (42%), Gaps = 12/129 (9%)
Query: 218 LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP-EITVERS-WVHTGEG 275
LG+ QL + G Y+C V+N +G + L+VLY P + V S EG
Sbjct: 550 LGKESQLNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSMSPGDQVMEG 609
Query: 276 FRAELVCTVLADPP-AEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCV 334
A L C A+PP + +W+ + S + L + V+ + G Y C
Sbjct: 610 KSATLTCESDANPPVSHYTWFDWN---------NQSLPHHSQKLRLEPVKVQHSGAYWCQ 660
Query: 335 ADNSLGRAR 343
NS+G+ R
Sbjct: 661 GTNSVGKGR 669
>U62631-1|AAB06448.1| 847|Homo sapiens B-cell receptor CD22-B
isoform protein.
Length = 847
Score = 70.9 bits (166), Expect = 1e-11
Identities = 62/201 (30%), Positives = 86/201 (42%), Gaps = 21/201 (10%)
Query: 153 CQISDR----VARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECR-AAGNP-VPTV 206
CQ+ D ++ D V + V P + R G + + C ++ NP TV
Sbjct: 219 CQLQDADGKFLSNDTVQ-LNVKHTPKLEIKVTPSDAIVREGDSVTMTCEVSSSNPEYTTV 277
Query: 207 TWHRLNDSSSRLGEGP-QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE-IT 264
+W L D +S + L L + + G Y C V N VGP E LQV Y PE T
Sbjct: 278 SW--LKDGTSLKKQNTFTLNLREVTKDQSGKYCCQVSNDVGPGRSEEVFLQVQYAPEPST 335
Query: 265 VERSWVHTGEGFRAELVCTVLADP-PAEVSWYQNSFPLSASERVTMSARGSNHTLLIADV 323
V+ EG + E +C LA+P P +WY N M R + + I +
Sbjct: 336 VQILHSPAVEGSQVEFLCMSLANPLPTNYTWYHNG--------KEMQGR-TEEKVHIPKI 386
Query: 324 QPEDFGNYSCVADNSLGRARR 344
P G YSCVA+N LG +R
Sbjct: 387 LPWHAGTYSCVAENILGTGQR 407
Score = 52.8 bits (121), Expect = 3e-06
Identities = 44/153 (28%), Positives = 63/153 (41%), Gaps = 6/153 (3%)
Query: 125 WETTRRITSEQHGNTNFRMIF-QDAGDYVCQISDRVAR--DQVHTVEVLVPPSVRASPET 181
WE R+ ++ NF I +DAG Y C +++ + + + T+EVL P +
Sbjct: 543 WEKNGRLLGKE-SQLNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSMS 601
Query: 182 RHVTARRGGAAVLECRAAGNP-VPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACT 240
G +A L C + NP V TW N+ S +L+L ++ H G Y C
Sbjct: 602 PGDQVMEGKSATLTCESDANPPVSHYTWFDWNNQSLPY-HSQKLRLEPVKVQHSGAYWCQ 660
Query: 241 VDNGVGPPVVTEFQLQVLYPPEITVERSWVHTG 273
N VG L V Y PE R V G
Sbjct: 661 GTNSVGKGRSPLSTLTVYYSPETIGRRVAVGLG 693
Score = 44.8 bits (101), Expect = 7e-04
Identities = 36/129 (27%), Positives = 55/129 (42%), Gaps = 12/129 (9%)
Query: 218 LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP-EITVERS-WVHTGEG 275
LG+ QL + G Y+C V+N +G + L+VLY P + V S EG
Sbjct: 550 LGKESQLNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSMSPGDQVMEG 609
Query: 276 FRAELVCTVLADPP-AEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCV 334
A L C A+PP + +W+ + S + L + V+ + G Y C
Sbjct: 610 KSATLTCESDANPPVSHYTWFDWN---------NQSLPYHSQKLRLEPVKVQHSGAYWCQ 660
Query: 335 ADNSLGRAR 343
NS+G+ R
Sbjct: 661 GTNSVGKGR 669
>EF064756-1|ABK41939.1| 847|Homo sapiens CD22 molecule protein.
Length = 847
Score = 70.9 bits (166), Expect = 1e-11
Identities = 62/201 (30%), Positives = 86/201 (42%), Gaps = 21/201 (10%)
Query: 153 CQISDR----VARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECR-AAGNP-VPTV 206
CQ+ D ++ D V + V P + R G + + C ++ NP TV
Sbjct: 219 CQLQDADGKFLSNDTVQ-LNVKHTPKLEIKVTPSDAIVREGDSVTMTCEVSSSNPEYTTV 277
Query: 207 TWHRLNDSSSRLGEGP-QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE-IT 264
+W L D +S + L L + + G Y C V N VGP E LQV Y PE T
Sbjct: 278 SW--LKDGTSLKKQNTFTLNLREVTKDQSGKYCCQVSNDVGPGRSEEVFLQVQYAPEPST 335
Query: 265 VERSWVHTGEGFRAELVCTVLADP-PAEVSWYQNSFPLSASERVTMSARGSNHTLLIADV 323
V+ EG + E +C LA+P P +WY N M R + + I +
Sbjct: 336 VQILHSPAVEGSQVEFLCMSLANPLPTNYTWYHNG--------KEMQGR-TEEKVHIPKI 386
Query: 324 QPEDFGNYSCVADNSLGRARR 344
P G YSCVA+N LG +R
Sbjct: 387 LPWHAGTYSCVAENILGTGQR 407
Score = 52.8 bits (121), Expect = 3e-06
Identities = 44/153 (28%), Positives = 63/153 (41%), Gaps = 6/153 (3%)
Query: 125 WETTRRITSEQHGNTNFRMIF-QDAGDYVCQISDRVAR--DQVHTVEVLVPPSVRASPET 181
WE R+ ++ NF I +DAG Y C +++ + + + T+EVL P +
Sbjct: 543 WEKNGRLLGKE-SQLNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSMS 601
Query: 182 RHVTARRGGAAVLECRAAGNP-VPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACT 240
G +A L C + NP V TW N+ S +L+L ++ H G Y C
Sbjct: 602 PGDQVMEGKSATLTCESDANPPVSHYTWFDWNNQSLPY-HSQKLRLEPVKVQHSGAYWCQ 660
Query: 241 VDNGVGPPVVTEFQLQVLYPPEITVERSWVHTG 273
N VG L V Y PE R V G
Sbjct: 661 GTNSVGKGRSPLSTLTVYYSPETIGRRVAVGLG 693
Score = 44.8 bits (101), Expect = 7e-04
Identities = 36/129 (27%), Positives = 55/129 (42%), Gaps = 12/129 (9%)
Query: 218 LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP-EITVERS-WVHTGEG 275
LG+ QL + G Y+C V+N +G + L+VLY P + V S EG
Sbjct: 550 LGKESQLNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSMSPGDQVMEG 609
Query: 276 FRAELVCTVLADPP-AEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCV 334
A L C A+PP + +W+ + S + L + V+ + G Y C
Sbjct: 610 KSATLTCESDANPPVSHYTWFDWN---------NQSLPYHSQKLRLEPVKVQHSGAYWCQ 660
Query: 335 ADNSLGRAR 343
NS+G+ R
Sbjct: 661 GTNSVGKGR 669
>BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein
protein.
Length = 1183
Score = 70.9 bits (166), Expect = 1e-11
Identities = 53/210 (25%), Positives = 85/210 (40%), Gaps = 11/210 (5%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+G+Y C + + HT+ V V + +++ G L CRA GNP P +
Sbjct: 328 DSGNYQCIAKNALGAIH-HTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRI 386
Query: 207 TW-------HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+W D SR +G + S ++ VY C N G + F +
Sbjct: 387 SWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE 446
Query: 260 PPEITVERSWVHTGEGFRAELV-CTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP I + ++ R L+ C P + W++ + + E + + N TL
Sbjct: 447 PPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE--NGTL 504
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEV 348
I Q + G Y+CVA N LG A+ V +
Sbjct: 505 EIPVAQKDSTGTYTCVARNKLGMAKNEVHL 534
Score = 66.1 bits (154), Expect = 3e-10
Identities = 66/252 (26%), Positives = 109/252 (43%), Gaps = 27/252 (10%)
Query: 167 VEVLV-PPSVRASPETRH-VTARRGGAAVLECRAAGNPVPTVTWHR------LNDSSSRL 218
V VL PP + T + V A R A+L+C G+P+PT+ W + L++ L
Sbjct: 441 VNVLAEPPRILTPANTLYQVIANR--PALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVL 498
Query: 219 GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRA 278
E L++ ++ G Y C N +G E L++ P I + + G
Sbjct: 499 HENGTLEIPVAQKDSTGTYTCVARNKLGM-AKNEVHLEIKDPTWIVKQPEYAVVQRGSMV 557
Query: 279 ELVCTVLADPPAEVS--WYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVAD 336
C V D ++ W +++ L + ER T+ +H L++ADV +D G Y+CVA+
Sbjct: 558 SFECKVKHDHTLSLTVLWLKDNRELPSDERFTVD---KDH-LVVADVSDDDSGTYTCVAN 613
Query: 337 NSLG--RARRHVEVSGRPGPARFTSPPLARAPHSYTLSFAV--DSYPPLDELRLLYRQLA 392
+L A + V P P F + S LS+ D+ P+ + + Y
Sbjct: 614 TTLDSVSASAVLSVVDVPNPP-FDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEY---- 668
Query: 393 INESFQQPGRWH 404
++ +PG WH
Sbjct: 669 -EDAMHKPGLWH 679
Score = 50.8 bits (116), Expect = 1e-05
Identities = 43/178 (24%), Positives = 66/178 (37%), Gaps = 7/178 (3%)
Query: 188 RGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLERHHGGVYACTVD 242
RG LEC A G P P + W + + + + LQ+ + G Y C
Sbjct: 278 RGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAK 337
Query: 243 NGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLS 302
N +G T P IT ++ V G L+C +P +SW N P+
Sbjct: 338 NALGAIHHTISVRVKAAPYWITAPQNLV-LSPGEDGTLICRANGNPKPRISWLTNGVPIE 396
Query: 303 ASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
+ S + T++ ++VQ Y C A N G + V+ P R +P
Sbjct: 397 IAPD-DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTP 453
>BC109306-1|AAI09307.1| 675|Homo sapiens CD22 protein protein.
Length = 675
Score = 70.9 bits (166), Expect = 1e-11
Identities = 62/201 (30%), Positives = 86/201 (42%), Gaps = 21/201 (10%)
Query: 153 CQISDR----VARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECR-AAGNP-VPTV 206
CQ+ D ++ D V + V P + R G + + C ++ NP TV
Sbjct: 47 CQLQDADGKFLSNDTVQ-LNVKHTPKLEIKVTPSDAIVREGDSVTMTCEVSSSNPEYTTV 105
Query: 207 TWHRLNDSSSRLGEGP-QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE-IT 264
+W L D +S + L L + + G Y C V N VGP E LQV Y PE T
Sbjct: 106 SW--LKDGTSLKKQNTFTLNLREVTKDQSGKYCCQVSNDVGPGRSEEVFLQVQYAPEPST 163
Query: 265 VERSWVHTGEGFRAELVCTVLADP-PAEVSWYQNSFPLSASERVTMSARGSNHTLLIADV 323
V+ EG + E +C LA+P P +WY N M R + + I +
Sbjct: 164 VQILHSPAVEGSQVEFLCMSLANPLPTNYTWYHNG--------KEMQGR-TEEKVHIPKI 214
Query: 324 QPEDFGNYSCVADNSLGRARR 344
P G YSCVA+N LG +R
Sbjct: 215 LPWHAGTYSCVAENILGTGQR 235
Score = 52.8 bits (121), Expect = 3e-06
Identities = 44/153 (28%), Positives = 63/153 (41%), Gaps = 6/153 (3%)
Query: 125 WETTRRITSEQHGNTNFRMIF-QDAGDYVCQISDRVAR--DQVHTVEVLVPPSVRASPET 181
WE R+ ++ NF I +DAG Y C +++ + + + T+EVL P +
Sbjct: 371 WEKNGRLLGKE-SQLNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSMS 429
Query: 182 RHVTARRGGAAVLECRAAGNP-VPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACT 240
G +A L C + NP V TW N+ S +L+L ++ H G Y C
Sbjct: 430 PGDQVMEGKSATLTCESDANPPVSHYTWFDWNNQSLPY-HSQKLRLEPVKVQHSGAYWCQ 488
Query: 241 VDNGVGPPVVTEFQLQVLYPPEITVERSWVHTG 273
N VG L V Y PE R V G
Sbjct: 489 GTNSVGKGRSPLSTLTVYYSPETIGRRVAVGLG 521
Score = 44.8 bits (101), Expect = 7e-04
Identities = 36/129 (27%), Positives = 55/129 (42%), Gaps = 12/129 (9%)
Query: 218 LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP-EITVERS-WVHTGEG 275
LG+ QL + G Y+C V+N +G + L+VLY P + V S EG
Sbjct: 378 LGKESQLNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSMSPGDQVMEG 437
Query: 276 FRAELVCTVLADPP-AEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCV 334
A L C A+PP + +W+ + S + L + V+ + G Y C
Sbjct: 438 KSATLTCESDANPPVSHYTWFDWN---------NQSLPYHSQKLRLEPVKVQHSGAYWCQ 488
Query: 335 ADNSLGRAR 343
NS+G+ R
Sbjct: 489 GTNSVGKGR 497
>AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein.
Length = 1299
Score = 70.9 bits (166), Expect = 1e-11
Identities = 53/210 (25%), Positives = 85/210 (40%), Gaps = 11/210 (5%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+G+Y C + + HT+ V V + +++ G L CRA GNP P +
Sbjct: 329 DSGNYQCIAKNALGAIH-HTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRI 387
Query: 207 TW-------HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+W D SR +G + S ++ VY C N G + F +
Sbjct: 388 SWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE 447
Query: 260 PPEITVERSWVHTGEGFRAELV-CTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP I + ++ R L+ C P + W++ + + E + + N TL
Sbjct: 448 PPRILTPANTLYQVIANRPALLDCAFFGSPLPTIQWFKGAKGSALHEDIYVLHE--NGTL 505
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEV 348
I Q + G Y+CVA N LG A+ V +
Sbjct: 506 EIPVAQKDSTGTYTCVARNKLGMAKNEVHL 535
Score = 63.7 bits (148), Expect = 1e-09
Identities = 51/183 (27%), Positives = 84/183 (45%), Gaps = 17/183 (9%)
Query: 167 VEVLV-PPSVRASPETRH-VTARRGGAAVLECRAAGNPVPTVTWHR------LNDSSSRL 218
V VL PP + T + V A R A+L+C G+P+PT+ W + L++ L
Sbjct: 442 VNVLAEPPRILTPANTLYQVIANR--PALLDCAFFGSPLPTIQWFKGAKGSALHEDIYVL 499
Query: 219 GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRA 278
E L++ ++ G Y C N +G E L++ P I + + G
Sbjct: 500 HENGTLEIPVAQKDSTGTYTCVARNKLGM-AKNEVHLEIKDPTWIVKQPEYAVVQRGSMV 558
Query: 279 ELVCTVLADPPAEVS--WYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVAD 336
C V D ++ W +++ L + ER T+ +H L++ADV +D G Y+CVA+
Sbjct: 559 SFECKVKHDHTLSLTVLWLKDNRELPSDERFTVD---KDH-LVVADVSDDDSGTYTCVAN 614
Query: 337 NSL 339
+L
Sbjct: 615 TTL 617
Score = 50.8 bits (116), Expect = 1e-05
Identities = 43/178 (24%), Positives = 66/178 (37%), Gaps = 7/178 (3%)
Query: 188 RGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLERHHGGVYACTVD 242
RG LEC A G P P + W + + + + LQ+ + G Y C
Sbjct: 279 RGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAK 338
Query: 243 NGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLS 302
N +G T P IT ++ V G L+C +P +SW N P+
Sbjct: 339 NALGAIHHTISVRVKAAPYWITAPQNLV-LSPGEDGTLICRANGNPKPRISWLTNGVPIE 397
Query: 303 ASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
+ S + T++ ++VQ Y C A N G + V+ P R +P
Sbjct: 398 IAPD-DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTP 454
>AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related cell
adhesion molecule /alternative carboxyl terminus
protein.
Length = 1236
Score = 70.9 bits (166), Expect = 1e-11
Identities = 53/210 (25%), Positives = 85/210 (40%), Gaps = 11/210 (5%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+G+Y C + + HT+ V V + +++ G L CRA GNP P +
Sbjct: 334 DSGNYQCIAKNALGAIH-HTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRI 392
Query: 207 TW-------HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+W D SR +G + S ++ VY C N G + F +
Sbjct: 393 SWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE 452
Query: 260 PPEITVERSWVHTGEGFRAELV-CTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP I + ++ R L+ C P + W++ + + E + + N TL
Sbjct: 453 PPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE--NGTL 510
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEV 348
I Q + G Y+CVA N LG A+ V +
Sbjct: 511 EIPVAQKDSTGTYTCVARNKLGMAKNEVHL 540
Score = 66.5 bits (155), Expect = 2e-10
Identities = 65/256 (25%), Positives = 108/256 (42%), Gaps = 25/256 (9%)
Query: 167 VEVLV-PPSVRASPETRH-VTARRGGAAVLECRAAGNPVPTVTWHR------LNDSSSRL 218
V VL PP + T + V A R A+L+C G+P+PT+ W + L++ L
Sbjct: 447 VNVLAEPPRILTPANTLYQVIANR--PALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVL 504
Query: 219 GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRA 278
E L++ ++ G Y C N +G E L++ P I + + G
Sbjct: 505 HENGTLEIPVAQKDSTGTYTCVARNKLGM-AKNEVHLEIKDPTWIVKQPEYAVVQRGSMV 563
Query: 279 ELVCTVLADPPAEVS--WYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVAD 336
C V D ++ W +++ L + ER T+ +H L++ADV +D G Y+CVA+
Sbjct: 564 SFECKVKHDHTLSLTVLWLKDNRELPSDERFTVD---KDH-LVVADVSDDDSGTYTCVAN 619
Query: 337 NSLGRARRHVEVS-GRPGPARFTSPPLARAPHSYTLSFAVD-----SYPPLDELRLLYRQ 390
+L +S P P + P L+ +D S+ P D+ +
Sbjct: 620 TTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITK 679
Query: 391 LAI--NESFQQPGRWH 404
I ++ +PG WH
Sbjct: 680 FIIEYEDAMHKPGLWH 695
Score = 50.8 bits (116), Expect = 1e-05
Identities = 43/178 (24%), Positives = 66/178 (37%), Gaps = 7/178 (3%)
Query: 188 RGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLERHHGGVYACTVD 242
RG LEC A G P P + W + + + + LQ+ + G Y C
Sbjct: 284 RGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAK 343
Query: 243 NGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLS 302
N +G T P IT ++ V G L+C +P +SW N P+
Sbjct: 344 NALGAIHHTISVRVKAAPYWITAPQNLV-LSPGEDGTLICRANGNPKPRISWLTNGVPIE 402
Query: 303 ASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
+ S + T++ ++VQ Y C A N G + V+ P R +P
Sbjct: 403 IAPD-DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTP 459
>AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related cell
adhesion molecule protein.
Length = 1308
Score = 70.9 bits (166), Expect = 1e-11
Identities = 53/210 (25%), Positives = 85/210 (40%), Gaps = 11/210 (5%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+G+Y C + + HT+ V V + +++ G L CRA GNP P +
Sbjct: 334 DSGNYQCIAKNALGAIH-HTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRI 392
Query: 207 TW-------HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+W D SR +G + S ++ VY C N G + F +
Sbjct: 393 SWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE 452
Query: 260 PPEITVERSWVHTGEGFRAELV-CTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
PP I + ++ R L+ C P + W++ + + E + + N TL
Sbjct: 453 PPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHE--NGTL 510
Query: 319 LIADVQPEDFGNYSCVADNSLGRARRHVEV 348
I Q + G Y+CVA N LG A+ V +
Sbjct: 511 EIPVAQKDSTGTYTCVARNKLGMAKNEVHL 540
Score = 66.5 bits (155), Expect = 2e-10
Identities = 65/256 (25%), Positives = 108/256 (42%), Gaps = 25/256 (9%)
Query: 167 VEVLV-PPSVRASPETRH-VTARRGGAAVLECRAAGNPVPTVTWHR------LNDSSSRL 218
V VL PP + T + V A R A+L+C G+P+PT+ W + L++ L
Sbjct: 447 VNVLAEPPRILTPANTLYQVIANR--PALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVL 504
Query: 219 GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRA 278
E L++ ++ G Y C N +G E L++ P I + + G
Sbjct: 505 HENGTLEIPVAQKDSTGTYTCVARNKLGM-AKNEVHLEIKDPTWIVKQPEYAVVQRGSMV 563
Query: 279 ELVCTVLADPPAEVS--WYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVAD 336
C V D ++ W +++ L + ER T+ +H L++ADV +D G Y+CVA+
Sbjct: 564 SFECKVKHDHTLSLTVLWLKDNRELPSDERFTVD---KDH-LVVADVSDDDSGTYTCVAN 619
Query: 337 NSLGRARRHVEVS-GRPGPARFTSPPLARAPHSYTLSFAVD-----SYPPLDELRLLYRQ 390
+L +S P P + P L+ +D S+ P D+ +
Sbjct: 620 TTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITK 679
Query: 391 LAI--NESFQQPGRWH 404
I ++ +PG WH
Sbjct: 680 FIIEYEDAMHKPGLWH 695
Score = 50.8 bits (116), Expect = 1e-05
Identities = 43/178 (24%), Positives = 66/178 (37%), Gaps = 7/178 (3%)
Query: 188 RGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLERHHGGVYACTVD 242
RG LEC A G P P + W + + + + LQ+ + G Y C
Sbjct: 284 RGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAK 343
Query: 243 NGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLS 302
N +G T P IT ++ V G L+C +P +SW N P+
Sbjct: 344 NALGAIHHTISVRVKAAPYWITAPQNLV-LSPGEDGTLICRANGNPKPRISWLTNGVPIE 402
Query: 303 ASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
+ S + T++ ++VQ Y C A N G + V+ P R +P
Sbjct: 403 IAPD-DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTP 459
>AB253795-1|BAF32758.1| 847|Homo sapiens CD22 antigen protein.
Length = 847
Score = 70.9 bits (166), Expect = 1e-11
Identities = 62/201 (30%), Positives = 86/201 (42%), Gaps = 21/201 (10%)
Query: 153 CQISDR----VARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECR-AAGNP-VPTV 206
CQ+ D ++ D V + V P + R G + + C ++ NP TV
Sbjct: 219 CQLQDADGKFLSNDTVQ-LNVKHTPKLEIKVTPSDAIVREGDSVTMTCEVSSSNPEYTTV 277
Query: 207 TWHRLNDSSSRLGEGP-QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE-IT 264
+W L D +S + L L + + G Y C V N VGP E LQV Y PE T
Sbjct: 278 SW--LKDGTSLKKQNTFTLNLREVTKDQSGKYCCQVSNDVGPGRSEEVFLQVQYAPEPST 335
Query: 265 VERSWVHTGEGFRAELVCTVLADP-PAEVSWYQNSFPLSASERVTMSARGSNHTLLIADV 323
V+ EG + E +C LA+P P +WY N M R + + I +
Sbjct: 336 VQILHSPAVEGSQVEFLCMSLANPLPTNYTWYHNG--------KEMQGR-TEEKVHIPKI 386
Query: 324 QPEDFGNYSCVADNSLGRARR 344
P G YSCVA+N LG +R
Sbjct: 387 LPWHAGTYSCVAENILGTGQR 407
Score = 52.8 bits (121), Expect = 3e-06
Identities = 44/153 (28%), Positives = 63/153 (41%), Gaps = 6/153 (3%)
Query: 125 WETTRRITSEQHGNTNFRMIF-QDAGDYVCQISDRVAR--DQVHTVEVLVPPSVRASPET 181
WE R+ ++ NF I +DAG Y C +++ + + + T+EVL P +
Sbjct: 543 WEKNGRLLGKE-SQLNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSMS 601
Query: 182 RHVTARRGGAAVLECRAAGNP-VPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACT 240
G +A L C + NP V TW N+ S +L+L ++ H G Y C
Sbjct: 602 PGDQVMEGKSATLTCESDANPPVSHYTWFDWNNQSLPY-HSQKLRLEPVKVQHSGAYWCQ 660
Query: 241 VDNGVGPPVVTEFQLQVLYPPEITVERSWVHTG 273
N VG L V Y PE R V G
Sbjct: 661 GTNSVGKGRSPLSTLTVYYSPETIGRRVAVGLG 693
Score = 44.8 bits (101), Expect = 7e-04
Identities = 36/129 (27%), Positives = 55/129 (42%), Gaps = 12/129 (9%)
Query: 218 LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP-EITVERS-WVHTGEG 275
LG+ QL + G Y+C V+N +G + L+VLY P + V S EG
Sbjct: 550 LGKESQLNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSMSPGDQVMEG 609
Query: 276 FRAELVCTVLADPP-AEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCV 334
A L C A+PP + +W+ + S + L + V+ + G Y C
Sbjct: 610 KSATLTCESDANPPVSHYTWFDWN---------NQSLPYHSQKLRLEPVKVQHSGAYWCQ 660
Query: 335 ADNSLGRAR 343
NS+G+ R
Sbjct: 661 GTNSVGKGR 669
>AB253794-1|BAF32757.1| 847|Homo sapiens CD22 antigen protein.
Length = 847
Score = 70.9 bits (166), Expect = 1e-11
Identities = 62/201 (30%), Positives = 86/201 (42%), Gaps = 21/201 (10%)
Query: 153 CQISDR----VARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECR-AAGNP-VPTV 206
CQ+ D ++ D V + V P + R G + + C ++ NP TV
Sbjct: 219 CQLQDADGKFLSNDTVQ-LNVKHTPKLEIKVTPSDAIVREGDSVTMTCEVSSSNPEYTTV 277
Query: 207 TWHRLNDSSSRLGEGP-QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE-IT 264
+W L D +S + L L + + G Y C V N VGP E LQV Y PE T
Sbjct: 278 SW--LKDGTSLKKQNTFTLNLREVTKDQSGKYCCQVSNDVGPGRSEEVFLQVQYAPEPST 335
Query: 265 VERSWVHTGEGFRAELVCTVLADP-PAEVSWYQNSFPLSASERVTMSARGSNHTLLIADV 323
V+ EG + E +C LA+P P +WY N M R + + I +
Sbjct: 336 VQILHSPAVEGSQVEFLCMSLANPLPTNYTWYHNG--------KEMQGR-TEEKVHIPKI 386
Query: 324 QPEDFGNYSCVADNSLGRARR 344
P G YSCVA+N LG +R
Sbjct: 387 LPWHAGTYSCVAENILGTGQR 407
Score = 52.8 bits (121), Expect = 3e-06
Identities = 44/153 (28%), Positives = 63/153 (41%), Gaps = 6/153 (3%)
Query: 125 WETTRRITSEQHGNTNFRMIF-QDAGDYVCQISDRVAR--DQVHTVEVLVPPSVRASPET 181
WE R+ ++ NF I +DAG Y C +++ + + + T+EVL P +
Sbjct: 543 WEKNGRLLGKE-SQLNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSMS 601
Query: 182 RHVTARRGGAAVLECRAAGNP-VPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACT 240
G +A L C + NP V TW N+ S +L+L ++ H G Y C
Sbjct: 602 PGDQVMEGKSATLTCESDANPPVSHYTWFDWNNQSLPY-HSQKLRLEPVKVQHSGAYWCQ 660
Query: 241 VDNGVGPPVVTEFQLQVLYPPEITVERSWVHTG 273
N VG L V Y PE R V G
Sbjct: 661 GTNSVGKGRSPLSTLTVYYSPETIGRRVAVGLG 693
Score = 44.8 bits (101), Expect = 7e-04
Identities = 36/129 (27%), Positives = 55/129 (42%), Gaps = 12/129 (9%)
Query: 218 LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP-EITVERS-WVHTGEG 275
LG+ QL + G Y+C V+N +G + L+VLY P + V S EG
Sbjct: 550 LGKESQLNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSMSPGDQVMEG 609
Query: 276 FRAELVCTVLADPP-AEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCV 334
A L C A+PP + +W+ + S + L + V+ + G Y C
Sbjct: 610 KSATLTCESDANPPVSHYTWFDWN---------NQSLPYHSQKLRLEPVKVQHSGAYWCQ 660
Query: 335 ADNSLGRAR 343
NS+G+ R
Sbjct: 661 GTNSVGKGR 669
>AB253793-1|BAF32756.1| 847|Homo sapiens CD22 antigen protein.
Length = 847
Score = 70.9 bits (166), Expect = 1e-11
Identities = 62/201 (30%), Positives = 86/201 (42%), Gaps = 21/201 (10%)
Query: 153 CQISDR----VARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECR-AAGNP-VPTV 206
CQ+ D ++ D V + V P + R G + + C ++ NP TV
Sbjct: 219 CQLQDADGKFLSNDTVQ-LNVKHTPKLEIKVTPSDAIVREGDSVTMTCEVSSSNPEYTTV 277
Query: 207 TWHRLNDSSSRLGEGP-QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE-IT 264
+W L D +S + L L + + G Y C V N VGP E LQV Y PE T
Sbjct: 278 SW--LKDGTSLKKQNTFTLNLREVTKDQSGKYCCQVSNDVGPGRSEEVFLQVQYAPEPST 335
Query: 265 VERSWVHTGEGFRAELVCTVLADP-PAEVSWYQNSFPLSASERVTMSARGSNHTLLIADV 323
V+ EG + E +C LA+P P +WY N M R + + I +
Sbjct: 336 VQILHSPAVEGSQVEFLCMSLANPLPTNYTWYHNG--------KEMQGR-TEEKVHIPKI 386
Query: 324 QPEDFGNYSCVADNSLGRARR 344
P G YSCVA+N LG +R
Sbjct: 387 LPWHAGTYSCVAENILGTGQR 407
Score = 52.8 bits (121), Expect = 3e-06
Identities = 44/153 (28%), Positives = 63/153 (41%), Gaps = 6/153 (3%)
Query: 125 WETTRRITSEQHGNTNFRMIF-QDAGDYVCQISDRVAR--DQVHTVEVLVPPSVRASPET 181
WE R+ ++ NF I +DAG Y C +++ + + + T+EVL P +
Sbjct: 543 WEKNGRLLGKE-SQLNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSMS 601
Query: 182 RHVTARRGGAAVLECRAAGNP-VPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACT 240
G +A L C + NP V TW N+ S +L+L ++ H G Y C
Sbjct: 602 PGDQVMEGKSATLTCESDANPPVSHYTWFDWNNQSLPY-HSQKLRLEPVKVQHSGAYWCQ 660
Query: 241 VDNGVGPPVVTEFQLQVLYPPEITVERSWVHTG 273
N VG L V Y PE R V G
Sbjct: 661 GTNSVGKGRSPLSTLTVYYSPETIGRRVAVGLG 693
Score = 44.8 bits (101), Expect = 7e-04
Identities = 36/129 (27%), Positives = 55/129 (42%), Gaps = 12/129 (9%)
Query: 218 LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP-EITVERS-WVHTGEG 275
LG+ QL + G Y+C V+N +G + L+VLY P + V S EG
Sbjct: 550 LGKESQLNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSMSPGDQVMEG 609
Query: 276 FRAELVCTVLADPP-AEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCV 334
A L C A+PP + +W+ + S + L + V+ + G Y C
Sbjct: 610 KSATLTCESDANPPVSHYTWFDWN---------NQSLPYHSQKLRLEPVKVQHSGAYWCQ 660
Query: 335 ADNSLGRAR 343
NS+G+ R
Sbjct: 661 GTNSVGKGR 669
>S61375-1|AAC18956.1| 662|Homo sapiens CD22 protein protein.
Length = 662
Score = 70.5 bits (165), Expect = 1e-11
Identities = 62/201 (30%), Positives = 85/201 (42%), Gaps = 21/201 (10%)
Query: 153 CQISDR----VARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAG-NP-VPTV 206
CQ+ D ++ D V + V P + R G + + C + NP TV
Sbjct: 99 CQLQDADGKFLSNDTVQ-LNVKHTPKLEIKVTPSDAIVREGDSVTMTCEVSSTNPEYTTV 157
Query: 207 TWHRLNDSSSRLGEGP-QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE-IT 264
+W L D +S + L L + + G Y C V N VGP E LQV Y PE T
Sbjct: 158 SW--LKDGTSLKKQNTFTLNLREVTKDQSGKYCCQVSNDVGPGRSEEVFLQVQYAPEPST 215
Query: 265 VERSWVHTGEGFRAELVCTVLADP-PAEVSWYQNSFPLSASERVTMSARGSNHTLLIADV 323
V+ EG + E +C LA+P P +WY N M R + + I +
Sbjct: 216 VQILHSPAVEGSQVEFLCMSLANPLPTNYTWYHNG--------KEMQGR-TEEKVHIPKI 266
Query: 324 QPEDFGNYSCVADNSLGRARR 344
P G YSCVA+N LG +R
Sbjct: 267 LPWHAGTYSCVAENILGTGQR 287
Score = 54.0 bits (124), Expect = 1e-06
Identities = 55/194 (28%), Positives = 79/194 (40%), Gaps = 10/194 (5%)
Query: 125 WETTRRITSEQHGNTNFRMIF-QDAGDYVCQISDRVAR--DQVHTVEVLVPPSVRASPET 181
WE R+ ++ NF I +DAG Y C +++ + + + T+EVL P +
Sbjct: 423 WEKNGRLLGKE-SQLNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSMS 481
Query: 182 RHVTARRGGAAVLECRAAGNP-VPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACT 240
G +A L C + NP V TW N+ S +L+L ++ H G Y C
Sbjct: 482 PGDQVMEGKSATLRCESDANPPVSHYTWFDWNNQSLPY-HSQKLRLEPVKVQHSGAYWCQ 540
Query: 241 VDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL--VCTV-LADPPAEVSWYQN 297
N VG L V Y PE R V G + +C + L AE S Q
Sbjct: 541 GTNSVGKGRSPLSTLTVYYSPETIGRRVAVGLGSCLAILILAICGLKLQRRDAESSEMQR 600
Query: 298 SFPLSASERVTMSA 311
P + + VT SA
Sbjct: 601 P-PRTCDDTVTYSA 613
Score = 43.6 bits (98), Expect = 0.002
Identities = 36/129 (27%), Positives = 55/129 (42%), Gaps = 12/129 (9%)
Query: 218 LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP-EITVERS-WVHTGEG 275
LG+ QL + G Y+C V+N +G + L+VLY P + V S EG
Sbjct: 430 LGKESQLNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSMSPGDQVMEG 489
Query: 276 FRAELVCTVLADPP-AEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCV 334
A L C A+PP + +W+ + S + L + V+ + G Y C
Sbjct: 490 KSATLRCESDANPPVSHYTWFDWN---------NQSLPYHSQKLRLEPVKVQHSGAYWCQ 540
Query: 335 ADNSLGRAR 343
NS+G+ R
Sbjct: 541 GTNSVGKGR 549
>BC104918-1|AAI04919.1| 1208|Homo sapiens CHL1 protein protein.
Length = 1208
Score = 70.1 bits (164), Expect = 2e-11
Identities = 66/244 (27%), Positives = 100/244 (40%), Gaps = 18/244 (7%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+QD G+Y C S+ + H V+V R + + + G +L C A G P P
Sbjct: 302 YQDKGNYRCTASNFLGT-ATHDFHVIVEEPPRWTKKPQSAVYSTGSNGILLCEAEGEPQP 360
Query: 205 TVTWHRLN----DSSSRLGE---GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
T+ W R+N D+ G+ ++ + L+ +H VY C N G ++ + V
Sbjct: 361 TIKW-RVNGSPVDNHPFAGDVVFPREISFTNLQPNHTAVYQCEASNVHGT-ILANANIDV 418
Query: 258 L--YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWY--QNSFPLSASERVTMSARG 313
+ P T + T G+ A L C A P A VSW + PL R + G
Sbjct: 419 VDVRPLIQTKDGENYATVVGYSAFLHCEFFASPEAVVSWQKVEEVKPLEG-RRYHIYENG 477
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTLSF 373
TL I ED G+YSC +N++G+ + R SP R P + L
Sbjct: 478 ---TLQINRTTEEDAGSYSCWVENAIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLEL 534
Query: 374 AVDS 377
+S
Sbjct: 535 HCES 538
Score = 55.2 bits (127), Expect = 5e-07
Identities = 42/178 (23%), Positives = 69/178 (38%), Gaps = 10/178 (5%)
Query: 168 EVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDS-----SSRLGEGP 222
++L+PP+ S + +T +G +LEC A G P P V W+++ ++ G
Sbjct: 236 KLLLPPTESGSESS--ITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGREAKENYGK 293
Query: 223 QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVC 282
L++ + G Y CT N +G +F + V PP T + G L+C
Sbjct: 294 TLKIENVSYQDKGNYRCTASNFLG-TATHDFHVIVEEPPRWTKKPQSAVYSTGSNGILLC 352
Query: 283 TVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
+P + W N P+ + ++QP Y C A N G
Sbjct: 353 EAEGEPQPTIKWRVNGSPV--DNHPFAGDVVFPREISFTNLQPNHTAVYQCEASNVHG 408
Score = 35.9 bits (79), Expect = 0.33
Identities = 30/106 (28%), Positives = 41/106 (38%), Gaps = 4/106 (3%)
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
++L PP + S + +G L C P +V W + L +
Sbjct: 236 KLLLPPTESGSESSITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGRE---AKENYG 292
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPP 361
TL I +V +D GNY C A N LG A V P R+T P
Sbjct: 293 KTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEE-PPRWTKKP 337
>AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell
adhesion molecule 2 protein.
Length = 2113
Score = 70.1 bits (164), Expect = 2e-11
Identities = 56/200 (28%), Positives = 77/200 (38%), Gaps = 11/200 (5%)
Query: 189 GGAAVLECRAAGNPVPTVTWHR----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNG 244
G L C A+G P+P + W + L S L +S L G Y C V N
Sbjct: 300 GHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITGLTISDLRTEDSGTYICEVTNT 359
Query: 245 VGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
G T L V+ P +T+ + TG G L C + P + WY+N+ +
Sbjct: 360 FGSAEATGI-LMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPD 418
Query: 305 ERVTMSARG-SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFT---SP 360
E + S RG SN TLLI Q G Y C A A+ ++ G R S
Sbjct: 419 EAI--SIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSE 476
Query: 361 PLARAPHSYTLSFAVDSYPP 380
+ ++L A PP
Sbjct: 477 KVVNPGEQFSLMCAAKGAPP 496
Score = 67.3 bits (157), Expect = 1e-10
Identities = 84/363 (23%), Positives = 149/363 (41%), Gaps = 21/363 (5%)
Query: 33 SFRTVVGDTLLLP-CQVQNLGSLVLLWRRAPAVLTAASLMVTRDERFRLVDGYNLQITDV 91
S R + +TLL+ Q + G+ R +++ D R+V ++ ++ +
Sbjct: 422 SIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNP 481
Query: 92 GPQIRYTVDVTIYENSETSVAL---AILGATGHTNVWETTRRITSEQHGNTNFRMIFQDA 148
G Q + AL I+ H T T+ H N I +D
Sbjct: 482 GEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQI-RDG 540
Query: 149 GDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
G Y C + V + + V PPS+RA R++TA G ++ CR G P ++
Sbjct: 541 GVYRCTARNLVGSAEYQARINVRGPPSIRAM---RNITAVAGRDTLINCRVIGYPYYSIK 597
Query: 208 WHR----LNDSSSRLG-EGPQLQLSRLERHHG-GVYACTVDNGVGPPVVTEFQLQVLYPP 261
W++ L D+ ++ E L+L+ +++ G Y C+V + + V PP
Sbjct: 598 WYKDALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPP 657
Query: 262 EITVERSWVHTGEGFRAELVCTVLA-DPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
I + G + C V + D P ++W ++ + + VT+ ++ +L I
Sbjct: 658 LIQ-PFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQI 716
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR---APHSYTLSFAVDS 377
+ V + GNY+C+A N+ R ++ R P RF P + + L+ +VD
Sbjct: 717 SSVSLKHNGNYTCIASNAAATVSRERQLIVRV-PPRFVVQPNNQDGIYGKAGVLNCSVDG 775
Query: 378 YPP 380
YPP
Sbjct: 776 YPP 778
Score = 59.3 bits (137), Expect = 3e-08
Identities = 57/242 (23%), Positives = 97/242 (40%), Gaps = 21/242 (8%)
Query: 128 TRRITSEQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTAR 187
T+RIT G T + +D+G Y+C++++ + + +++ P + + + +
Sbjct: 333 TKRIT----GLTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDP-LHVTLTPKKLKTG 387
Query: 188 RGGAAVLECRAAGNPVPTVTWHR-----LNDS--SSRLGEGPQLQLSRLERHHGGVYACT 240
G +L C G+P T+ W+R L D S R L ++ ++ H G Y C
Sbjct: 388 IGSTVILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCF 447
Query: 241 VDNGVGPPVVTEFQLQVLY--PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS 298
+F + L P I S G + L+C PP V+W +
Sbjct: 448 ATRKA--QTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDD 505
Query: 299 FPL--SASERV---TMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
P+ S R TMS + + + Q D G Y C A N +G A ++ R
Sbjct: 506 EPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGP 565
Query: 354 PA 355
P+
Sbjct: 566 PS 567
Score = 55.6 bits (128), Expect = 4e-07
Identities = 58/226 (25%), Positives = 88/226 (38%), Gaps = 22/226 (9%)
Query: 149 GDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
G+Y C S+ A + + V VPP P + G A VL C G P P V
Sbjct: 725 GNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQD--GIYGKAGVLNCSVDGYPPPKVM 782
Query: 208 WHRLNDSSSRLGEGP-----QLQL----SRLERH----HGGVYACTVDNGVGPPVVTEFQ 254
W S + P ++Q+ S L RH G Y C NGVG +
Sbjct: 783 WKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMF 842
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE--RVTMSAR 312
L V P IT + +G EL CT + P + W + + R ++ +
Sbjct: 843 LTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATK 902
Query: 313 -GSNHTLLIADVQPEDFGN---YSCVADNSLGRARRHVEVSGRPGP 354
+ + ++P D G+ +SC A NS G R ++++ + P
Sbjct: 903 DNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPP 948
Score = 39.5 bits (88), Expect = 0.027
Identities = 46/183 (25%), Positives = 74/183 (40%), Gaps = 18/183 (9%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARG---SNHTLLIADVQPEDFGNYSCVAD 336
L C + DP V W ++S ++ V+M +N TLL+ V+ ED G Y+C A
Sbjct: 1369 LPCNSVGDPAPAVKWTKDSE--DSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTAT 1426
Query: 337 NSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINES 396
N+ G V + + P + + S TL++ P D R + S
Sbjct: 1427 NTGGFDTIIVNLLVQVPPDQPRLTVSKTSASSITLTWI-----PGDNGGSSIRGFVLQYS 1481
Query: 397 FQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVSDIFQFH 456
W DV +++ S +L L+ Y+ + AKN G +S+I +
Sbjct: 1482 VDNSEEWKDVFISSSER--------SFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAK 1533
Query: 457 TLG 459
T G
Sbjct: 1534 THG 1536
Score = 32.7 bits (71), Expect = 3.1
Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 4/67 (5%)
Query: 146 QDAGDYVCQISDRVARD--QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
+D G Y+CQ S+ V D + + V +P + + P T A +G A L C A G
Sbjct: 820 EDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNT--TIAIKGHAKELNCTARGERP 877
Query: 204 PTVTWHR 210
+ W +
Sbjct: 878 IIIRWEK 884
>AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell
adhesion molecule DSCAML1 protein.
Length = 2053
Score = 70.1 bits (164), Expect = 2e-11
Identities = 56/200 (28%), Positives = 77/200 (38%), Gaps = 11/200 (5%)
Query: 189 GGAAVLECRAAGNPVPTVTWHR----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNG 244
G L C A+G P+P + W + L S L +S L G Y C V N
Sbjct: 240 GHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITGLTISDLRTEDSGTYICEVTNT 299
Query: 245 VGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
G T L V+ P +T+ + TG G L C + P + WY+N+ +
Sbjct: 300 FGSAEATGI-LMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPD 358
Query: 305 ERVTMSARG-SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFT---SP 360
E + S RG SN TLLI Q G Y C A A+ ++ G R S
Sbjct: 359 EAI--SIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSE 416
Query: 361 PLARAPHSYTLSFAVDSYPP 380
+ ++L A PP
Sbjct: 417 KVVNPGEQFSLMCAAKGAPP 436
Score = 67.3 bits (157), Expect = 1e-10
Identities = 84/363 (23%), Positives = 149/363 (41%), Gaps = 21/363 (5%)
Query: 33 SFRTVVGDTLLLP-CQVQNLGSLVLLWRRAPAVLTAASLMVTRDERFRLVDGYNLQITDV 91
S R + +TLL+ Q + G+ R +++ D R+V ++ ++ +
Sbjct: 362 SIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNP 421
Query: 92 GPQIRYTVDVTIYENSETSVAL---AILGATGHTNVWETTRRITSEQHGNTNFRMIFQDA 148
G Q + AL I+ H T T+ H N I +D
Sbjct: 422 GEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQI-RDG 480
Query: 149 GDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
G Y C + V + + V PPS+RA R++TA G ++ CR G P ++
Sbjct: 481 GVYRCTARNLVGSAEYQARINVRGPPSIRAM---RNITAVAGRDTLINCRVIGYPYYSIK 537
Query: 208 WHR----LNDSSSRLG-EGPQLQLSRLERHHG-GVYACTVDNGVGPPVVTEFQLQVLYPP 261
W++ L D+ ++ E L+L+ +++ G Y C+V + + V PP
Sbjct: 538 WYKDALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPP 597
Query: 262 EITVERSWVHTGEGFRAELVCTVLA-DPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
I + G + C V + D P ++W ++ + + VT+ ++ +L I
Sbjct: 598 LIQ-PFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQI 656
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR---APHSYTLSFAVDS 377
+ V + GNY+C+A N+ R ++ R P RF P + + L+ +VD
Sbjct: 657 SSVSLKHNGNYTCIASNAAATVSRERQLIVRV-PPRFVVQPNNQDGIYGKAGVLNCSVDG 715
Query: 378 YPP 380
YPP
Sbjct: 716 YPP 718
Score = 59.3 bits (137), Expect = 3e-08
Identities = 57/242 (23%), Positives = 97/242 (40%), Gaps = 21/242 (8%)
Query: 128 TRRITSEQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTAR 187
T+RIT G T + +D+G Y+C++++ + + +++ P + + + +
Sbjct: 273 TKRIT----GLTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDP-LHVTLTPKKLKTG 327
Query: 188 RGGAAVLECRAAGNPVPTVTWHR-----LNDS--SSRLGEGPQLQLSRLERHHGGVYACT 240
G +L C G+P T+ W+R L D S R L ++ ++ H G Y C
Sbjct: 328 IGSTVILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCF 387
Query: 241 VDNGVGPPVVTEFQLQVLY--PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS 298
+F + L P I S G + L+C PP V+W +
Sbjct: 388 ATRKA--QTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDD 445
Query: 299 FPL--SASERV---TMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
P+ S R TMS + + + Q D G Y C A N +G A ++ R
Sbjct: 446 EPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGP 505
Query: 354 PA 355
P+
Sbjct: 506 PS 507
Score = 55.6 bits (128), Expect = 4e-07
Identities = 58/226 (25%), Positives = 88/226 (38%), Gaps = 22/226 (9%)
Query: 149 GDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
G+Y C S+ A + + V VPP P + G A VL C G P P V
Sbjct: 665 GNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQD--GIYGKAGVLNCSVDGYPPPKVM 722
Query: 208 WHRLNDSSSRLGEGP-----QLQL----SRLERH----HGGVYACTVDNGVGPPVVTEFQ 254
W S + P ++Q+ S L RH G Y C NGVG +
Sbjct: 723 WKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMF 782
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE--RVTMSAR 312
L V P IT + +G EL CT + P + W + + R ++ +
Sbjct: 783 LTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATK 842
Query: 313 -GSNHTLLIADVQPEDFGN---YSCVADNSLGRARRHVEVSGRPGP 354
+ + ++P D G+ +SC A NS G R ++++ + P
Sbjct: 843 DNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPP 888
Score = 39.5 bits (88), Expect = 0.027
Identities = 46/183 (25%), Positives = 74/183 (40%), Gaps = 18/183 (9%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARG---SNHTLLIADVQPEDFGNYSCVAD 336
L C + DP V W ++S ++ V+M +N TLL+ V+ ED G Y+C A
Sbjct: 1309 LPCNSVGDPAPAVKWTKDSE--DSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTAT 1366
Query: 337 NSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINES 396
N+ G V + + P + + S TL++ P D R + S
Sbjct: 1367 NTGGFDTIIVNLLVQVPPDQPRLTVSKTSASSITLTWI-----PGDNGGSSIRGFVLQYS 1421
Query: 397 FQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVSDIFQFH 456
W DV +++ S +L L+ Y+ + AKN G +S+I +
Sbjct: 1422 VDNSEEWKDVFISSSER--------SFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAK 1473
Query: 457 TLG 459
T G
Sbjct: 1474 THG 1476
Score = 32.7 bits (71), Expect = 3.1
Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 4/67 (5%)
Query: 146 QDAGDYVCQISDRVARD--QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
+D G Y+CQ S+ V D + + V +P + + P T A +G A L C A G
Sbjct: 760 EDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNT--TIAIKGHAKELNCTARGERP 817
Query: 204 PTVTWHR 210
+ W +
Sbjct: 818 IIIRWEK 824
>AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell
adhesion molecule like-protein 1a protein.
Length = 2053
Score = 70.1 bits (164), Expect = 2e-11
Identities = 56/200 (28%), Positives = 77/200 (38%), Gaps = 11/200 (5%)
Query: 189 GGAAVLECRAAGNPVPTVTWHR----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNG 244
G L C A+G P+P + W + L S L +S L G Y C V N
Sbjct: 240 GHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITGLTISDLRTEDSGTYICEVTNT 299
Query: 245 VGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
G T L V+ P +T+ + TG G L C + P + WY+N+ +
Sbjct: 300 FGSAEATGI-LMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPD 358
Query: 305 ERVTMSARG-SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFT---SP 360
E + S RG SN TLLI Q G Y C A A+ ++ G R S
Sbjct: 359 EAI--SIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSE 416
Query: 361 PLARAPHSYTLSFAVDSYPP 380
+ ++L A PP
Sbjct: 417 KVVNPGEQFSLMCAAKGAPP 436
Score = 61.3 bits (142), Expect = 8e-09
Identities = 61/246 (24%), Positives = 109/246 (44%), Gaps = 16/246 (6%)
Query: 146 QDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G Y C + V + + V PPS+RA R++TA G ++ CR G P
Sbjct: 478 RDGGVYRCTARNLVGSAEYQARINVRGPPSIRAM---RNITAVAGRDTLINCRVIGYPYY 534
Query: 205 TVTWHR----LNDSSSRLG-EGPQLQLSRLERHHG-GVYACTVDNGVGPPVVTEFQLQVL 258
++ W++ L D+ ++ E L+L+ +++ G Y C+V + + V
Sbjct: 535 SIKWYKDALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVK 594
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLA-DPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP I + G + C V + D P ++W ++ + + VT+ ++ +
Sbjct: 595 VPPLIQ-PFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSS 653
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR---APHSYTLSFA 374
L I+ V + GN +C+A N+ R ++ R P RF P + + L+ +
Sbjct: 654 LQISSVSLKHNGNDTCIASNAAATVSRERQLIVRV-PPRFVVQPNNQDGIYGKAGVLNCS 712
Query: 375 VDSYPP 380
VD YPP
Sbjct: 713 VDGYPP 718
Score = 59.7 bits (138), Expect = 2e-08
Identities = 56/242 (23%), Positives = 95/242 (39%), Gaps = 21/242 (8%)
Query: 128 TRRITSEQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTAR 187
T+RIT G T + +D+G Y+C++++ + + +++ P + + + +
Sbjct: 273 TKRIT----GLTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDP-LHVTLTPKKLKTG 327
Query: 188 RGGAAVLECRAAGNPVPTVTWHR-----LNDS--SSRLGEGPQLQLSRLERHHGGVYACT 240
G +L C G+P T+ W+R L D S R L ++ ++ H G Y C
Sbjct: 328 IGSTVILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCF 387
Query: 241 VDNGVGPPVVTEFQLQVLYP--PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS 298
+F + L P I S G + L+C PP V+W +
Sbjct: 388 ATRKA--QTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDD 445
Query: 299 FPL--SASERVTMSARGSNHTLLIADV---QPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
P+ S R T+ +V Q D G Y C A N +G A ++ R
Sbjct: 446 EPIVRDGSHRTNQYTMSDGTTISYMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGP 505
Query: 354 PA 355
P+
Sbjct: 506 PS 507
Score = 52.4 bits (120), Expect = 4e-06
Identities = 53/200 (26%), Positives = 77/200 (38%), Gaps = 19/200 (9%)
Query: 148 AGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
+G Y C + + Q + L + R G L C A G P PTVT
Sbjct: 381 SGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVT 440
Query: 208 W------------HRLNDSSSRLGEG-PQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
W HR N + G + ++ + GGVY CT N VG + +
Sbjct: 441 WALDDEPIVRDGSHRTNQYTMSDGTTISYMNVTGPQIRDGGVYRCTARNLVG-SAEYQAR 499
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
+ V PP I R+ + G + C V+ P + WY+++ L + R + G
Sbjct: 500 INVRGPPSIRAMRN-ITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENG- 557
Query: 315 NHTLLIADVQP-EDFGNYSC 333
TL + DVQ D G Y C
Sbjct: 558 --TLKLTDVQKGMDEGEYLC 575
Score = 51.6 bits (118), Expect = 6e-06
Identities = 57/226 (25%), Positives = 87/226 (38%), Gaps = 22/226 (9%)
Query: 149 GDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
G+ C S+ A + + V VPP P + G A VL C G P P V
Sbjct: 665 GNDTCIASNAAATVSRERQLIVRVPPRFVVQPNNQD--GIYGKAGVLNCSVDGYPPPKVM 722
Query: 208 WHRLNDSSSRLGEGP-----QLQL----SRLERH----HGGVYACTVDNGVGPPVVTEFQ 254
W S + P ++Q+ S L RH G Y C NGVG +
Sbjct: 723 WKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMF 782
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE--RVTMSAR 312
L V P IT + +G EL CT + P + W + + R ++ +
Sbjct: 783 LTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATK 842
Query: 313 -GSNHTLLIADVQPEDFGN---YSCVADNSLGRARRHVEVSGRPGP 354
+ + ++P D G+ +SC A NS G R ++++ + P
Sbjct: 843 DNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPP 888
Score = 39.5 bits (88), Expect = 0.027
Identities = 46/183 (25%), Positives = 74/183 (40%), Gaps = 18/183 (9%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARG---SNHTLLIADVQPEDFGNYSCVAD 336
L C + DP V W ++S ++ V+M +N TLL+ V+ ED G Y+C A
Sbjct: 1309 LPCNSVGDPAPAVKWTKDSE--DSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTAT 1366
Query: 337 NSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINES 396
N+ G V + + P + + S TL++ P D R + S
Sbjct: 1367 NTGGFDTIIVNLLVQVPPDQPRLTVSKTSASSITLTWI-----PGDNGGSSIRGFVLQYS 1421
Query: 397 FQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVSDIFQFH 456
W DV +++ S +L L+ Y+ + AKN G +S+I +
Sbjct: 1422 VDNSEEWKDVFISSSER--------SFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAK 1473
Query: 457 TLG 459
T G
Sbjct: 1474 THG 1476
Score = 32.7 bits (71), Expect = 3.1
Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 4/67 (5%)
Query: 146 QDAGDYVCQISDRVARD--QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
+D G Y+CQ S+ V D + + V +P + + P T A +G A L C A G
Sbjct: 760 EDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNT--TIAIKGHAKELNCTARGERP 817
Query: 204 PTVTWHR 210
+ W +
Sbjct: 818 IIIRWEK 824
>AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein.
Length = 2828
Score = 70.1 bits (164), Expect = 2e-11
Identities = 64/222 (28%), Positives = 89/222 (40%), Gaps = 22/222 (9%)
Query: 146 QDAGDYVCQISDRVARDQ-VHTVEVLVP-PSVRASPETRHVTARRGGAAVLECRAAGNPV 203
QD G Y+C S+ D+ V + V V P + AS + VT G +EC A G P
Sbjct: 1921 QDRGQYMCTASNLHGLDRMVVLLSVTVQQPQILAS-HYQDVTVYLGDTIAMECLAKGTPA 1979
Query: 204 PTVTW--------HRLNDSSSR--LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
P ++W ++ SR L E L + GVY C N G +
Sbjct: 1980 PQISWIFPDRRVWQTVSPVESRITLHENRTLSIKEASFSDRGVYKCVASNAAGADSLAIR 2039
Query: 254 QLQVLYPPEITVER-SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
PP I E+ + G + CT A P V W R +
Sbjct: 2040 LHVAALPPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRWVLGD---GTQIRPSQFLH 2096
Query: 313 GS-----NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
G+ N TL I ++ P+D G Y CVA N +G ARR V+++
Sbjct: 2097 GNLFVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRTVQLN 2138
Score = 65.3 bits (152), Expect = 5e-10
Identities = 60/237 (25%), Positives = 99/237 (41%), Gaps = 25/237 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+DAGDY+C ++V D V V+V++ P+ E GG ++C A G P P
Sbjct: 2214 KDAGDYLCVARNKVGDDYVVLKVDVVMKPAKIEHKEENDHKVFYGGDLKVDCVATGLPNP 2273
Query: 205 TVTWH-----------RLNDSSSR-----LGEGPQLQLSRLERHHGGVYACTVDNGVGPP 248
++W + +DS R + L + + G Y C +N VG
Sbjct: 2274 EISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGDYTCFAENQVGKD 2333
Query: 249 VVTEFQLQVLYPPEITVERSW--VHTGEGFRAELVCTVLADPPAEVSWYQ--NSFPLSAS 304
+ +++V+ P +++ V G + C +P +V+W N ++S
Sbjct: 2334 EM-RVRVKVVTAPATIRNKTYLAVQVPYGDVVTVACEAKGEPMPKVTWLSPTNKVIPTSS 2392
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPP 361
E+ + G TLLI Q D GNY+C+ NS G R+ V + P + P
Sbjct: 2393 EKYQIYQDG---TLLIQKAQRSDSGNYTCLVRNSAGEDRKTVWIHVNVQPPKINGNP 2446
Score = 62.5 bits (145), Expect = 3e-09
Identities = 60/240 (25%), Positives = 101/240 (42%), Gaps = 21/240 (8%)
Query: 128 TRRITSEQHGNTNFRMI-FQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVT 185
T+R +G F + ++ GDY C ++V +D++ V+V+ P+ + V
Sbjct: 2298 TKRYVVFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRNKTYLAVQ 2357
Query: 186 ARRGGAAVLECRAAGNPVPTVTW----HRLNDSSS---RLGEGPQLQLSRLERHHGGVYA 238
G + C A G P+P VTW +++ +SS ++ + L + + +R G Y
Sbjct: 2358 VPYGDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQRSDSGNYT 2417
Query: 239 CTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHT-----GEGFRAELVCTVLADPPAEVS 293
C V N G T + + PP+I + + T G R + C P V
Sbjct: 2418 CLVRNSAGEDRKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVL 2477
Query: 294 W-YQNSFPLSA---SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
W + L A R+T+ GS L I ++ D C+A N G AR V+++
Sbjct: 2478 WAFPEGVVLPAPYYGNRITVHGNGS---LDIRSLRKSDSVQLVCMARNEGGEARLIVQLT 2534
Score = 55.2 bits (127), Expect = 5e-07
Identities = 59/247 (23%), Positives = 91/247 (36%), Gaps = 16/247 (6%)
Query: 130 RITSEQHGNTNFRMIFQ-DAGDYVCQISDRVARDQVHTVEVLVPPSVRA---SPETRHVT 185
RIT +G+ + R + + D+ VC + ++ ++ P + P + +T
Sbjct: 2494 RITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLIVQLTVLEPMEKPIFHDPISEKIT 2553
Query: 186 ARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQ---------LQLSRLERHHGGV 236
A G L C AAG P P++ W N + + G+ Q L +S L G
Sbjct: 2554 AMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVDAGA 2613
Query: 237 YACTVDNGVGPPVVTEFQLQVLYPPEITVE-RSWVHTGEGFRAELVCTVLADPPAEVSW- 294
Y C N G L+V PE + + V G +L CT SW
Sbjct: 2614 YRCVARNAAG-HTERLVSLKVGLKPEANKQYHNLVSIINGETLKLPCTPPGAGQGRFSWT 2672
Query: 295 YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
N L + + + N TL + + D G Y C + G + + V P
Sbjct: 2673 LPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPVIVIAYP 2732
Query: 355 ARFTSPP 361
R TS P
Sbjct: 2733 PRITSEP 2739
Score = 54.0 bits (124), Expect = 1e-06
Identities = 61/235 (25%), Positives = 95/235 (40%), Gaps = 28/235 (11%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPET----RHVTARRGGAAVLECRAAGN 201
+D+G Y C ++ V + TV++ V + + T R R GG L+C A+G+
Sbjct: 2115 KDSGRYECVAANLVGSAR-RTVQLNVQRAAANARITGTSPRRTDVRYGGTLKLDCSASGD 2173
Query: 202 PVPTVTWHRLN----------DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVT 251
P P + W + DS ++ L + + G Y C N VG V
Sbjct: 2174 PWPRILWRLPSKRMIDALFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVGDDYVV 2233
Query: 252 EFQLQVLYPPEITVERSWVHT---GEGFRAELVCTVLADPPAEVSW------YQNSFPLS 302
V+ P +I + H G + + V T L +P E+SW NSF S
Sbjct: 2234 LKVDVVMKPAKIEHKEENDHKVFYGGDLKVDCVATGLPNP--EISWSLPDGSLVNSFMQS 2291
Query: 303 --ASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
+ R +N TL +V + G+Y+C A+N +G+ V V PA
Sbjct: 2292 DDSGGRTKRYVVFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPA 2346
Score = 48.0 bits (109), Expect = 8e-05
Identities = 49/187 (26%), Positives = 75/187 (40%), Gaps = 25/187 (13%)
Query: 172 PPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDS-----SSRLG-----EG 221
P + SP+T VTA V C A G P P VTW +++ ++R+ +
Sbjct: 1853 PQILTKSPQTVSVTAETD--TVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKN 1910
Query: 222 PQLQLSRLERHHGGVYACTVDNGVG-PPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + +++ G Y CT N G +V + V P + V G +
Sbjct: 1911 GTLVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTVQQPQILASHYQDVTVYLGDTIAM 1970
Query: 281 VCTVLADPPAEVSW-------YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
C P ++SW +Q P+ + R+T+ N TL I + D G Y C
Sbjct: 1971 ECLAKGTPAPQISWIFPDRRVWQTVSPVES--RITLH---ENRTLSIKEASFSDRGVYKC 2025
Query: 334 VADNSLG 340
VA N+ G
Sbjct: 2026 VASNAAG 2032
Score = 41.1 bits (92), Expect = 0.009
Identities = 44/173 (25%), Positives = 64/173 (36%), Gaps = 15/173 (8%)
Query: 182 RHVTARRGGAAVLECRAAGNPVPTVTW---------HRLNDSSSRLG--EGPQLQLSRLE 230
R T GG L C + P++ W ++D S+ L++ +E
Sbjct: 487 RDQTVLEGGPCQLSCNVKASESPSIFWVLPDGSILKAPMDDPDSKFSILSSGWLRIKSME 546
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGE--GFRAELVCTVLADP 288
G+Y C + +++ V P E+ V G+ G L C LA P
Sbjct: 547 PSDSGLYQCIAQVRDEMDRMV-YRVLVQSPSTQPAEKDTVTIGKNPGESVTLPCNALAIP 605
Query: 289 PAEVSWY-QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
A +SW N ++ + N TL I VQ D G Y CVA N G
Sbjct: 606 EAHLSWILPNRRIINDLANTSHVYMLPNGTLSIPKVQVSDSGYYRCVAVNQQG 658
Score = 38.7 bits (86), Expect = 0.047
Identities = 28/115 (24%), Positives = 47/115 (40%), Gaps = 6/115 (5%)
Query: 126 ETTRRITSEQHGNTNFR--MIFQDAGDYVCQISDRVARD--QVHTVEVLVPPSVRASPET 181
+T R++ +G R +F D G YVC++ + + + PP + + P T
Sbjct: 2683 QTLGRVSLLDNGTLTVREASVF-DRGTYVCRMETEYGPSVTSIPVIVIAYPPRITSEP-T 2740
Query: 182 RHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGV 236
+ R G L C A G P +TW + S + G +L +R G +
Sbjct: 2741 PVIYTRPGNTVKLNCMAMGIPKADITWELPDKSHLKAGVQARLYGNRFLHPQGSL 2795
Score = 31.5 bits (68), Expect = 7.1
Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 2/70 (2%)
Query: 282 CTVLADPPAEVSWYQNSFP--LSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
C P V+W + S ++ + R+ N TL+I VQ +D G Y C A N
Sbjct: 1875 CEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKNGTLVIRKVQVQDRGQYMCTASNLH 1934
Query: 340 GRARRHVEVS 349
G R V +S
Sbjct: 1935 GLDRMVVLLS 1944
>AF002246-1|AAB60937.1| 1224|Homo sapiens neural cell adhesion
molecule protein.
Length = 1224
Score = 70.1 bits (164), Expect = 2e-11
Identities = 66/244 (27%), Positives = 100/244 (40%), Gaps = 18/244 (7%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+QD G+Y C S+ + H V+V R + + + G +L C A G P P
Sbjct: 318 YQDKGNYRCTASNFLGT-ATHDFHVIVEEPPRWTKKPQSAVYSTGSNGILLCEAEGEPQP 376
Query: 205 TVTWHRLN----DSSSRLGE---GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
T+ W R+N D+ G+ ++ + L+ +H VY C N G ++ + V
Sbjct: 377 TIKW-RVNGSPVDNHPFAGDVVFPREISFTNLQPNHTAVYQCEASNVHGT-ILANANIDV 434
Query: 258 L--YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWY--QNSFPLSASERVTMSARG 313
+ P T + T G+ A L C A P A VSW + PL R + G
Sbjct: 435 VDVRPLIQTKDGENYATVVGYSAFLHCEFFASPEAVVSWQKVEEVKPLEG-RRYHIYENG 493
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTLSF 373
TL I ED G+YSC +N++G+ + R SP R P + L
Sbjct: 494 ---TLQINRTTEEDAGSYSCWVENAIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLEL 550
Query: 374 AVDS 377
+S
Sbjct: 551 HCES 554
Score = 55.2 bits (127), Expect = 5e-07
Identities = 42/178 (23%), Positives = 69/178 (38%), Gaps = 10/178 (5%)
Query: 168 EVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDS-----SSRLGEGP 222
++L+PP+ S + +T +G +LEC A G P P V W+++ ++ G
Sbjct: 252 KLLLPPTESGSESS--ITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGREAKENYGK 309
Query: 223 QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVC 282
L++ + G Y CT N +G +F + V PP T + G L+C
Sbjct: 310 TLKIENVSYQDKGNYRCTASNFLG-TATHDFHVIVEEPPRWTKKPQSAVYSTGSNGILLC 368
Query: 283 TVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
+P + W N P+ + ++QP Y C A N G
Sbjct: 369 EAEGEPQPTIKWRVNGSPV--DNHPFAGDVVFPREISFTNLQPNHTAVYQCEASNVHG 424
Score = 35.9 bits (79), Expect = 0.33
Identities = 30/106 (28%), Positives = 41/106 (38%), Gaps = 4/106 (3%)
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
++L PP + S + +G L C P +V W + L +
Sbjct: 252 KLLLPPTESGSESSITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGRE---AKENYG 308
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPP 361
TL I +V +D GNY C A N LG A V P R+T P
Sbjct: 309 KTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEE-PPRWTKKP 353
>AB209329-1|BAD92566.1| 1210|Homo sapiens Neural cell adhesion
molecule variant protein.
Length = 1210
Score = 70.1 bits (164), Expect = 2e-11
Identities = 66/244 (27%), Positives = 100/244 (40%), Gaps = 18/244 (7%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+QD G+Y C S+ + H V+V R + + + G +L C A G P P
Sbjct: 304 YQDKGNYRCTASNFLGT-ATHDFHVIVEEPPRWTKKPQSAVYSTGSNGILLCEAEGEPQP 362
Query: 205 TVTWHRLN----DSSSRLGE---GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
T+ W R+N D+ G+ ++ + L+ +H VY C N G ++ + V
Sbjct: 363 TIKW-RVNGSPVDNHPFAGDVVFPREISFTNLQPNHTAVYQCEASNVHGT-ILANANIDV 420
Query: 258 L--YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWY--QNSFPLSASERVTMSARG 313
+ P T + T G+ A L C A P A VSW + PL R + G
Sbjct: 421 VDVRPLIQTKDGENYATVVGYSAFLHCEFFASPEAVVSWQKVEEVKPLEG-RRYHIYENG 479
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTLSF 373
TL I ED G+YSC +N++G+ + R SP R P + L
Sbjct: 480 ---TLQINRTTEEDAGSYSCWVENAIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLEL 536
Query: 374 AVDS 377
+S
Sbjct: 537 HCES 540
Score = 55.2 bits (127), Expect = 5e-07
Identities = 42/178 (23%), Positives = 69/178 (38%), Gaps = 10/178 (5%)
Query: 168 EVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDS-----SSRLGEGP 222
++L+PP+ S + +T +G +LEC A G P P V W+++ ++ G
Sbjct: 238 KLLLPPTESGSESS--ITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGREAKENYGK 295
Query: 223 QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVC 282
L++ + G Y CT N +G +F + V PP T + G L+C
Sbjct: 296 TLKIENVSYQDKGNYRCTASNFLG-TATHDFHVIVEEPPRWTKKPQSAVYSTGSNGILLC 354
Query: 283 TVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
+P + W N P+ + ++QP Y C A N G
Sbjct: 355 EAEGEPQPTIKWRVNGSPV--DNHPFAGDVVFPREISFTNLQPNHTAVYQCEASNVHG 410
Score = 35.9 bits (79), Expect = 0.33
Identities = 30/106 (28%), Positives = 41/106 (38%), Gaps = 4/106 (3%)
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
++L PP + S + +G L C P +V W + L +
Sbjct: 238 KLLLPPTESGSESSITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGRE---AKENYG 294
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPP 361
TL I +V +D GNY C A N LG A V P R+T P
Sbjct: 295 KTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEE-PPRWTKKP 339
>AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein.
Length = 2092
Score = 70.1 bits (164), Expect = 2e-11
Identities = 56/200 (28%), Positives = 77/200 (38%), Gaps = 11/200 (5%)
Query: 189 GGAAVLECRAAGNPVPTVTWHR----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNG 244
G L C A+G P+P + W + L S L +S L G Y C V N
Sbjct: 279 GHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITGLTISDLRTEDSGTYICEVTNT 338
Query: 245 VGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
G T L V+ P +T+ + TG G L C + P + WY+N+ +
Sbjct: 339 FGSAEATGI-LMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPD 397
Query: 305 ERVTMSARG-SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFT---SP 360
E + S RG SN TLLI Q G Y C A A+ ++ G R S
Sbjct: 398 EAI--SIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSE 455
Query: 361 PLARAPHSYTLSFAVDSYPP 380
+ ++L A PP
Sbjct: 456 KVVNPGEQFSLMCAAKGAPP 475
Score = 67.3 bits (157), Expect = 1e-10
Identities = 84/363 (23%), Positives = 149/363 (41%), Gaps = 21/363 (5%)
Query: 33 SFRTVVGDTLLLP-CQVQNLGSLVLLWRRAPAVLTAASLMVTRDERFRLVDGYNLQITDV 91
S R + +TLL+ Q + G+ R +++ D R+V ++ ++ +
Sbjct: 401 SIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNP 460
Query: 92 GPQIRYTVDVTIYENSETSVAL---AILGATGHTNVWETTRRITSEQHGNTNFRMIFQDA 148
G Q + AL I+ H T T+ H N I +D
Sbjct: 461 GEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQI-RDG 519
Query: 149 GDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
G Y C + V + + V PPS+RA R++TA G ++ CR G P ++
Sbjct: 520 GVYRCTARNLVGSAEYQARINVRGPPSIRAM---RNITAVAGRDTLINCRVIGYPYYSIK 576
Query: 208 WHR----LNDSSSRLG-EGPQLQLSRLERHHG-GVYACTVDNGVGPPVVTEFQLQVLYPP 261
W++ L D+ ++ E L+L+ +++ G Y C+V + + V PP
Sbjct: 577 WYKDALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPP 636
Query: 262 EITVERSWVHTGEGFRAELVCTVLA-DPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
I + G + C V + D P ++W ++ + + VT+ ++ +L I
Sbjct: 637 LIQ-PFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQI 695
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR---APHSYTLSFAVDS 377
+ V + GNY+C+A N+ R ++ R P RF P + + L+ +VD
Sbjct: 696 SSVSLKHNGNYTCIASNAAATVSRERQLIVRV-PPRFVVQPNNQDGIYGKAGVLNCSVDG 754
Query: 378 YPP 380
YPP
Sbjct: 755 YPP 757
Score = 59.3 bits (137), Expect = 3e-08
Identities = 57/242 (23%), Positives = 97/242 (40%), Gaps = 21/242 (8%)
Query: 128 TRRITSEQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTAR 187
T+RIT G T + +D+G Y+C++++ + + +++ P + + + +
Sbjct: 312 TKRIT----GLTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDP-LHVTLTPKKLKTG 366
Query: 188 RGGAAVLECRAAGNPVPTVTWHR-----LNDS--SSRLGEGPQLQLSRLERHHGGVYACT 240
G +L C G+P T+ W+R L D S R L ++ ++ H G Y C
Sbjct: 367 IGSTVILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCF 426
Query: 241 VDNGVGPPVVTEFQLQVLY--PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS 298
+F + L P I S G + L+C PP V+W +
Sbjct: 427 ATRKA--QTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDD 484
Query: 299 FPL--SASERV---TMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
P+ S R TMS + + + Q D G Y C A N +G A ++ R
Sbjct: 485 EPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGP 544
Query: 354 PA 355
P+
Sbjct: 545 PS 546
Score = 55.6 bits (128), Expect = 4e-07
Identities = 58/226 (25%), Positives = 88/226 (38%), Gaps = 22/226 (9%)
Query: 149 GDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
G+Y C S+ A + + V VPP P + G A VL C G P P V
Sbjct: 704 GNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQD--GIYGKAGVLNCSVDGYPPPKVM 761
Query: 208 WHRLNDSSSRLGEGP-----QLQL----SRLERH----HGGVYACTVDNGVGPPVVTEFQ 254
W S + P ++Q+ S L RH G Y C NGVG +
Sbjct: 762 WKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMF 821
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE--RVTMSAR 312
L V P IT + +G EL CT + P + W + + R ++ +
Sbjct: 822 LTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATK 881
Query: 313 -GSNHTLLIADVQPEDFGN---YSCVADNSLGRARRHVEVSGRPGP 354
+ + ++P D G+ +SC A NS G R ++++ + P
Sbjct: 882 DNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPP 927
Score = 39.5 bits (88), Expect = 0.027
Identities = 46/183 (25%), Positives = 74/183 (40%), Gaps = 18/183 (9%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARG---SNHTLLIADVQPEDFGNYSCVAD 336
L C + DP V W ++S ++ V+M +N TLL+ V+ ED G Y+C A
Sbjct: 1348 LPCNSVGDPAPAVKWTKDSE--DSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTAT 1405
Query: 337 NSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINES 396
N+ G V + + P + + S TL++ P D R + S
Sbjct: 1406 NTGGFDTIIVNLLVQVPPDQPRLTVSKTSASSITLTWI-----PGDNGGSSIRGFVLQYS 1460
Query: 397 FQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVSDIFQFH 456
W DV +++ S +L L+ Y+ + AKN G +S+I +
Sbjct: 1461 VDNSEEWKDVFISSSER--------SFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAK 1512
Query: 457 TLG 459
T G
Sbjct: 1513 THG 1515
Score = 32.7 bits (71), Expect = 3.1
Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 4/67 (5%)
Query: 146 QDAGDYVCQISDRVARD--QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
+D G Y+CQ S+ V D + + V +P + + P T A +G A L C A G
Sbjct: 799 EDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNT--TIAIKGHAKELNCTARGERP 856
Query: 204 PTVTWHR 210
+ W +
Sbjct: 857 IIIRWEK 863
>AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1157
Score = 68.9 bits (161), Expect = 4e-11
Identities = 65/250 (26%), Positives = 103/250 (41%), Gaps = 21/250 (8%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLG------E 220
V VL P SP + + L+C G+P+PT+ W + S+ G E
Sbjct: 417 VSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYE 476
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L++ + + G+Y C N +G + +L+V P I G +L
Sbjct: 477 NGSLEIKMIRKEDQGIYTCVATNILGK-AENQVRLEVKDPTRIYRMPEDQVARRGTTVQL 535
Query: 281 VCTVLADPPAE--VSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNS 338
C V DP + VSW ++ PL R+ + + +L I V D G+Y+CVA
Sbjct: 536 ECRVKHDPSLKLTVSWLKDDEPLYIGNRM----KKEDDSLTIFGVAERDQGSYTCVASTE 591
Query: 339 LGR--ARRHVEVSGRPG-PARFTSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINE 395
L + A+ ++ V GRP P LA T + P+ + + + + +
Sbjct: 592 LDQDLAKAYLTVLGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEE----D 647
Query: 396 SFQQPGRWHD 405
F QPG WHD
Sbjct: 648 QF-QPGVWHD 656
Score = 62.1 bits (144), Expect = 4e-09
Identities = 58/224 (25%), Positives = 90/224 (40%), Gaps = 12/224 (5%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+D+G+Y C S+++ + HT+ V V + E +++ G L CRA GNP PT
Sbjct: 303 EDSGEYFCLASNKMGSIR-HTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPT 361
Query: 206 VTW-------HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
V W + +R G + + VY C N G + F +
Sbjct: 362 VQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLD 421
Query: 259 YPPEITVERS-WVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP + R+ + R L C P + W++N S + N +
Sbjct: 422 VPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNG-QGSNLDGGNYHVY-ENGS 479
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPP 361
L I ++ ED G Y+CVA N LG+A V + + P R P
Sbjct: 480 LEIKMIRKEDQGIYTCVATNILGKAENQVRLEVK-DPTRIYRMP 522
Score = 54.0 bits (124), Expect = 1e-06
Identities = 46/179 (25%), Positives = 66/179 (36%), Gaps = 9/179 (5%)
Query: 188 RGGAAVLECRAAGNPVPTVTWHRL-----NDSSSRLGEGPQLQLSRLERHHGGVYACTVD 242
RG +LEC A+G P P + W++ +D + L+++ + G Y C
Sbjct: 254 RGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLAS 313
Query: 243 NGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL- 301
N +G + ++V P E + G LVC +P V W N PL
Sbjct: 314 NKMG-SIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQ 372
Query: 302 SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
SA G T++ D Q Y C N G + VS P R SP
Sbjct: 373 SAPPNPNREVAGD--TIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSP 429
Score = 44.8 bits (101), Expect = 7e-04
Identities = 46/186 (24%), Positives = 76/186 (40%), Gaps = 22/186 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQL 226
+++ PP++ H+ R ++EC A GNP P+ W R N + + P++ +
Sbjct: 29 MDLTQPPTITKQSAKDHIVDPRDNI-LIECEAKGNPAPSFHWTR-NSRFFNIAKDPRVSM 86
Query: 227 SRLE-------------RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVER-SWVHT 272
R + G Y C N G + +LQV P E V
Sbjct: 87 RRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVV 146
Query: 273 GEGFRAELVCTVLADPPAEVSWYQNSF--PLSASERVTMSARGSNHTLLIADVQPEDF-G 329
EG L C P+ V ++ +S P++ +RV ++G N L ++V +D
Sbjct: 147 QEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRV---SQGHNGDLYFSNVMLQDMQT 203
Query: 330 NYSCVA 335
+YSC A
Sbjct: 204 DYSCNA 209
Score = 34.7 bits (76), Expect = 0.76
Identities = 38/138 (27%), Positives = 61/138 (44%), Gaps = 15/138 (10%)
Query: 135 QHGNTNFRMIF-QDAGDYVCQISDRV--ARDQVHTVEVLVPPSVRASPETRHVTARRGGA 191
++G+ +MI +D G Y C ++ + A +QV +EV P + PE + ARRG
Sbjct: 476 ENGSLEIKMIRKEDQGIYTCVATNILGKAENQVR-LEVKDPTRIYRMPEDQ--VARRGTT 532
Query: 192 AVLECRAAGNP--VPTVTWHRLNDSSSRLG-----EGPQLQLSRLERHHGGVYACTVDNG 244
LECR +P TV+W + +D +G E L + + G Y C
Sbjct: 533 VQLECRVKHDPSLKLTVSWLK-DDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTE 591
Query: 245 VGPPVVTEFQLQVLYPPE 262
+ + + L VL P+
Sbjct: 592 LDQDLAKAY-LTVLGRPD 608
>AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1174
Score = 68.9 bits (161), Expect = 4e-11
Identities = 65/250 (26%), Positives = 103/250 (41%), Gaps = 21/250 (8%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLG------E 220
V VL P SP + + L+C G+P+PT+ W + S+ G E
Sbjct: 434 VSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYE 493
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L++ + + G+Y C N +G + +L+V P I G +L
Sbjct: 494 NGSLEIKMIRKEDQGIYTCVATNILGK-AENQVRLEVKDPTRIYRMPEDQVARRGTTVQL 552
Query: 281 VCTVLADPPAE--VSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNS 338
C V DP + VSW ++ PL R+ + + +L I V D G+Y+CVA
Sbjct: 553 ECRVKHDPSLKLTVSWLKDDEPLYIGNRM----KKEDDSLTIFGVAERDQGSYTCVASTE 608
Query: 339 LGR--ARRHVEVSGRPG-PARFTSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINE 395
L + A+ ++ V GRP P LA T + P+ + + + + +
Sbjct: 609 LDQDLAKAYLTVLGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEE----D 664
Query: 396 SFQQPGRWHD 405
F QPG WHD
Sbjct: 665 QF-QPGVWHD 673
Score = 62.1 bits (144), Expect = 4e-09
Identities = 58/224 (25%), Positives = 90/224 (40%), Gaps = 12/224 (5%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+D+G+Y C S+++ + HT+ V V + E +++ G L CRA GNP PT
Sbjct: 320 EDSGEYFCLASNKMGSIR-HTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPT 378
Query: 206 VTW-------HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
V W + +R G + + VY C N G + F +
Sbjct: 379 VQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLD 438
Query: 259 YPPEITVERS-WVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP + R+ + R L C P + W++N S + N +
Sbjct: 439 VPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNG-QGSNLDGGNYHVY-ENGS 496
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPP 361
L I ++ ED G Y+CVA N LG+A V + + P R P
Sbjct: 497 LEIKMIRKEDQGIYTCVATNILGKAENQVRLEVK-DPTRIYRMP 539
Score = 54.0 bits (124), Expect = 1e-06
Identities = 46/179 (25%), Positives = 66/179 (36%), Gaps = 9/179 (5%)
Query: 188 RGGAAVLECRAAGNPVPTVTWHRL-----NDSSSRLGEGPQLQLSRLERHHGGVYACTVD 242
RG +LEC A+G P P + W++ +D + L+++ + G Y C
Sbjct: 271 RGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLAS 330
Query: 243 NGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL- 301
N +G + ++V P E + G LVC +P V W N PL
Sbjct: 331 NKMG-SIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQ 389
Query: 302 SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
SA G T++ D Q Y C N G + VS P R SP
Sbjct: 390 SAPPNPNREVAGD--TIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSP 446
Score = 44.8 bits (101), Expect = 7e-04
Identities = 46/186 (24%), Positives = 76/186 (40%), Gaps = 22/186 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQL 226
+++ PP++ H+ R ++EC A GNP P+ W R N + + P++ +
Sbjct: 29 MDLTQPPTITKQSAKDHIVDPRDNI-LIECEAKGNPAPSFHWTR-NSRFFNIAKDPRVSM 86
Query: 227 SRLE-------------RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVER-SWVHT 272
R + G Y C N G + +LQV P E V
Sbjct: 87 RRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVV 146
Query: 273 GEGFRAELVCTVLADPPAEVSWYQNSF--PLSASERVTMSARGSNHTLLIADVQPEDF-G 329
EG L C P+ V ++ +S P++ +RV ++G N L ++V +D
Sbjct: 147 QEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRV---SQGHNGDLYFSNVMLQDMQT 203
Query: 330 NYSCVA 335
+YSC A
Sbjct: 204 DYSCNA 209
Score = 34.7 bits (76), Expect = 0.76
Identities = 38/138 (27%), Positives = 61/138 (44%), Gaps = 15/138 (10%)
Query: 135 QHGNTNFRMIF-QDAGDYVCQISDRV--ARDQVHTVEVLVPPSVRASPETRHVTARRGGA 191
++G+ +MI +D G Y C ++ + A +QV +EV P + PE + ARRG
Sbjct: 493 ENGSLEIKMIRKEDQGIYTCVATNILGKAENQVR-LEVKDPTRIYRMPEDQ--VARRGTT 549
Query: 192 AVLECRAAGNP--VPTVTWHRLNDSSSRLG-----EGPQLQLSRLERHHGGVYACTVDNG 244
LECR +P TV+W + +D +G E L + + G Y C
Sbjct: 550 VQLECRVKHDPSLKLTVSWLK-DDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTE 608
Query: 245 VGPPVVTEFQLQVLYPPE 262
+ + + L VL P+
Sbjct: 609 LDQDLAKAY-LTVLGRPD 625
>AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant 1
protein.
Length = 836
Score = 68.9 bits (161), Expect = 4e-11
Identities = 65/250 (26%), Positives = 103/250 (41%), Gaps = 21/250 (8%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLG------E 220
V VL P SP + + L+C G+P+PT+ W + S+ G E
Sbjct: 231 VSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYE 290
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L++ + + G+Y C N +G + +L+V P I G +L
Sbjct: 291 NGSLEIKMIRKEDQGIYTCVATNILGK-AENQVRLEVKDPTRIYRMPEDQVARRGTTVQL 349
Query: 281 VCTVLADPPAE--VSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNS 338
C V DP + VSW ++ PL R+ + + +L I V D G+Y+CVA
Sbjct: 350 ECRVKHDPSLKLTVSWLKDDEPLYIGNRM----KKEDDSLTIFGVAERDQGSYTCVASTE 405
Query: 339 LGR--ARRHVEVSGRPG-PARFTSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINE 395
L + A+ ++ V GRP P LA T + P+ + + + + +
Sbjct: 406 LDQDLAKAYLTVLGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEE----D 461
Query: 396 SFQQPGRWHD 405
F QPG WHD
Sbjct: 462 QF-QPGVWHD 470
Score = 62.1 bits (144), Expect = 4e-09
Identities = 58/224 (25%), Positives = 90/224 (40%), Gaps = 12/224 (5%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+D+G+Y C S+++ + HT+ V V + E +++ G L CRA GNP PT
Sbjct: 117 EDSGEYFCLASNKMGSIR-HTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPT 175
Query: 206 VTW-------HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
V W + +R G + + VY C N G + F +
Sbjct: 176 VQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLD 235
Query: 259 YPPEITVERS-WVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP + R+ + R L C P + W++N S + N +
Sbjct: 236 VPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNG-QGSNLDGGNYHVY-ENGS 293
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPP 361
L I ++ ED G Y+CVA N LG+A V + + P R P
Sbjct: 294 LEIKMIRKEDQGIYTCVATNILGKAENQVRLEVK-DPTRIYRMP 336
Score = 54.0 bits (124), Expect = 1e-06
Identities = 46/179 (25%), Positives = 66/179 (36%), Gaps = 9/179 (5%)
Query: 188 RGGAAVLECRAAGNPVPTVTWHRL-----NDSSSRLGEGPQLQLSRLERHHGGVYACTVD 242
RG +LEC A+G P P + W++ +D + L+++ + G Y C
Sbjct: 68 RGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLAS 127
Query: 243 NGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL- 301
N +G + ++V P E + G LVC +P V W N PL
Sbjct: 128 NKMG-SIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQ 186
Query: 302 SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
SA G T++ D Q Y C N G + VS P R SP
Sbjct: 187 SAPPNPNREVAGD--TIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSP 243
Score = 34.7 bits (76), Expect = 0.76
Identities = 38/138 (27%), Positives = 61/138 (44%), Gaps = 15/138 (10%)
Query: 135 QHGNTNFRMIF-QDAGDYVCQISDRV--ARDQVHTVEVLVPPSVRASPETRHVTARRGGA 191
++G+ +MI +D G Y C ++ + A +QV +EV P + PE + ARRG
Sbjct: 290 ENGSLEIKMIRKEDQGIYTCVATNILGKAENQVR-LEVKDPTRIYRMPEDQ--VARRGTT 346
Query: 192 AVLECRAAGNP--VPTVTWHRLNDSSSRLG-----EGPQLQLSRLERHHGGVYACTVDNG 244
LECR +P TV+W + +D +G E L + + G Y C
Sbjct: 347 VQLECRVKHDPSLKLTVSWLK-DDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTE 405
Query: 245 VGPPVVTEFQLQVLYPPE 262
+ + + L VL P+
Sbjct: 406 LDQDLAKAY-LTVLGRPD 422
>AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein.
Length = 1222
Score = 68.9 bits (161), Expect = 4e-11
Identities = 65/250 (26%), Positives = 103/250 (41%), Gaps = 21/250 (8%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLG------E 220
V VL P SP + + L+C G+P+PT+ W + S+ G E
Sbjct: 487 VSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYE 546
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L++ + + G+Y C N +G + +L+V P I G +L
Sbjct: 547 NGSLEIKMIRKEDQGIYTCVATNILGK-AENQVRLEVKDPTRIYRMPEDQVARRGTTVQL 605
Query: 281 VCTVLADPPAE--VSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNS 338
C V DP + VSW ++ PL R+ + + +L I V D G+Y+CVA
Sbjct: 606 ECRVKHDPSLKLTVSWLKDDEPLYIGNRM----KKEDDSLTIFGVAERDQGSYTCVASTE 661
Query: 339 LGR--ARRHVEVSGRPG-PARFTSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINE 395
L + A+ ++ V GRP P LA T + P+ + + + + +
Sbjct: 662 LDQDLAKAYLTVLGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEE----D 717
Query: 396 SFQQPGRWHD 405
F QPG WHD
Sbjct: 718 QF-QPGVWHD 726
Score = 62.1 bits (144), Expect = 4e-09
Identities = 58/224 (25%), Positives = 90/224 (40%), Gaps = 12/224 (5%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+D+G+Y C S+++ + HT+ V V + E +++ G L CRA GNP PT
Sbjct: 373 EDSGEYFCLASNKMGSIR-HTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPT 431
Query: 206 VTW-------HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
V W + +R G + + VY C N G + F +
Sbjct: 432 VQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLD 491
Query: 259 YPPEITVERS-WVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
PP + R+ + R L C P + W++N S + N +
Sbjct: 492 VPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNG-QGSNLDGGNYHVY-ENGS 549
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPP 361
L I ++ ED G Y+CVA N LG+A V + + P R P
Sbjct: 550 LEIKMIRKEDQGIYTCVATNILGKAENQVRLEVK-DPTRIYRMP 592
Score = 54.0 bits (124), Expect = 1e-06
Identities = 46/179 (25%), Positives = 66/179 (36%), Gaps = 9/179 (5%)
Query: 188 RGGAAVLECRAAGNPVPTVTWHRL-----NDSSSRLGEGPQLQLSRLERHHGGVYACTVD 242
RG +LEC A+G P P + W++ +D + L+++ + G Y C
Sbjct: 324 RGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLAS 383
Query: 243 NGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL- 301
N +G + ++V P E + G LVC +P V W N PL
Sbjct: 384 NKMG-SIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQ 442
Query: 302 SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
SA G T++ D Q Y C N G + VS P R SP
Sbjct: 443 SAPPNPNREVAGD--TIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSP 499
Score = 44.8 bits (101), Expect = 7e-04
Identities = 46/186 (24%), Positives = 76/186 (40%), Gaps = 22/186 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQL 226
+++ PP++ H+ R ++EC A GNP P+ W R N + + P++ +
Sbjct: 82 MDLTQPPTITKQSAKDHIVDPRDNI-LIECEAKGNPAPSFHWTR-NSRFFNIAKDPRVSM 139
Query: 227 SRLE-------------RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVER-SWVHT 272
R + G Y C N G + +LQV P E V
Sbjct: 140 RRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVV 199
Query: 273 GEGFRAELVCTVLADPPAEVSWYQNSF--PLSASERVTMSARGSNHTLLIADVQPEDF-G 329
EG L C P+ V ++ +S P++ +RV ++G N L ++V +D
Sbjct: 200 QEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRV---SQGHNGDLYFSNVMLQDMQT 256
Query: 330 NYSCVA 335
+YSC A
Sbjct: 257 DYSCNA 262
Score = 34.7 bits (76), Expect = 0.76
Identities = 38/138 (27%), Positives = 61/138 (44%), Gaps = 15/138 (10%)
Query: 135 QHGNTNFRMIF-QDAGDYVCQISDRV--ARDQVHTVEVLVPPSVRASPETRHVTARRGGA 191
++G+ +MI +D G Y C ++ + A +QV +EV P + PE + ARRG
Sbjct: 546 ENGSLEIKMIRKEDQGIYTCVATNILGKAENQVR-LEVKDPTRIYRMPEDQ--VARRGTT 602
Query: 192 AVLECRAAGNP--VPTVTWHRLNDSSSRLG-----EGPQLQLSRLERHHGGVYACTVDNG 244
LECR +P TV+W + +D +G E L + + G Y C
Sbjct: 603 VQLECRVKHDPSLKLTVSWLK-DDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTE 661
Query: 245 VGPPVVTEFQLQVLYPPE 262
+ + + L VL P+
Sbjct: 662 LDQDLAKAY-LTVLGRPD 678
>BC036569-1|AAH36569.1| 627|Homo sapiens CNTN1 protein protein.
Length = 627
Score = 68.5 bits (160), Expect = 5e-11
Identities = 56/230 (24%), Positives = 98/230 (42%), Gaps = 18/230 (7%)
Query: 141 FRMIFQDAGDYVCQISDRVARDQVHT-VEVL-VPPSVRASPETRHVTARRGGAAVLECRA 198
+ + F++AG Y C + + +++L + P+ +P + + A +GG ++EC+
Sbjct: 379 YDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKP 438
Query: 199 AGNPVPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
P P +W + +N S + E L+++ + R+ GG+Y C +N G T
Sbjct: 439 KAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTG- 497
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS--WYQNSFPLSASERVTMSA 311
L + P I + G A + C DP +++ W N + + ++
Sbjct: 498 TLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQ 557
Query: 312 RG----SNHTLLIADVQPEDFGNYSCVA----DNSLGRARRHVEVSGRPG 353
R SN LLI + Q + G Y+C A DNS A V R G
Sbjct: 558 RNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGKNRKG 607
Score = 58.8 bits (136), Expect = 4e-08
Identities = 56/184 (30%), Positives = 76/184 (41%), Gaps = 16/184 (8%)
Query: 190 GAAVLECRAAGNPVPTVTWHRLND----SSSRLGE-GPQLQLSRLERHH-GGVYACTVDN 243
G L CRA +P P W N +S R G L ++ ++ G+Y C N
Sbjct: 59 GKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLASN 118
Query: 244 GVGPPVVTEFQLQVLY----PPEITVERSWVHTGEGFRAELVCTVLADPPAEVS--WYQN 297
G TE L Y PPE ER V EG L+C P ++S W N
Sbjct: 119 NYGMVRSTEATLSFGYLDPFPPE---ERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLN 175
Query: 298 SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC-VADNSLGRARRHVEVSGRPGPAR 356
FP+ + +N L IA+V+ D GNYSC V+ S+ ++ + P P R
Sbjct: 176 EFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPER 235
Query: 357 FTSP 360
T P
Sbjct: 236 TTKP 239
Score = 56.4 bits (130), Expect = 2e-07
Identities = 56/234 (23%), Positives = 90/234 (38%), Gaps = 27/234 (11%)
Query: 129 RRITSEQHGNTNFRMI-FQDAGDYVCQISDRVARDQVHTVEV-LVP-PSVRASP------ 179
RR S+ +GN + D G+Y C +S V + + L+P P P
Sbjct: 186 RRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPYPADIV 245
Query: 180 -ETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGE----GPQLQLSRLERHHG 234
+ + V A G LEC A GNPVP + W ++ + E G L++ ++
Sbjct: 246 VQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNIQLEDE 305
Query: 235 GVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSW 294
G+Y C +N G + ++ V PE + G C P + W
Sbjct: 306 GIYECEAENIRGKD-KHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRW 364
Query: 295 YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
+N + E L + DV E+ G Y C+A+N+ G + E+
Sbjct: 365 LKNGYAYHKGE------------LRLYDVTFENAGMYQCIAENTYGAIYANAEL 406
>AK097578-1|BAC05109.1| 600|Homo sapiens protein ( Homo sapiens
cDNA FLJ40259 fis, clone TESTI2025486. ).
Length = 600
Score = 68.5 bits (160), Expect = 5e-11
Identities = 66/240 (27%), Positives = 103/240 (42%), Gaps = 28/240 (11%)
Query: 115 ILGATGHTNVWETTRRITSEQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLV--P 172
+LGA+G V + + +TS +D G Y C+ + + VHT +LV P
Sbjct: 21 LLGASGKYQVSDGSLTVTSVSR---------EDRGAYTCRAYS-IQGEAVHTTHLLVQGP 70
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVP-TVTWHRL-------NDSSSR---LGEG 221
P + + PE ++T A+L CRA P T TW+ ND R L +G
Sbjct: 71 PFIVSPPE--NITVNISQDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDG 128
Query: 222 PQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELV 281
L + R++ G Y C N +G L V YP + ++ G +
Sbjct: 129 T-LIIFRVKPEDSGKYTCVPSNSLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIR 187
Query: 282 CTVLADPPAE-VSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
C V A+PPA V W ++ PL + + + + ++ I + E G Y+CV N+LG
Sbjct: 188 CPVDAEPPATVVKWNKDGRPLQVEKNLGWTLM-EDGSIRIEEATEEALGTYTCVPYNTLG 246
Score = 62.1 bits (144), Expect = 4e-09
Identities = 60/197 (30%), Positives = 79/197 (40%), Gaps = 12/197 (6%)
Query: 194 LECRAAGNPVPTVTWHR----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPV 249
+ C A GNP P VTW + L S L ++ + R G Y C + G V
Sbjct: 1 MTCTAFGNPKPIVTWLKEGTLLGASGKYQVSDGSLTVTSVSREDRGAYTCRAYSIQGEAV 60
Query: 250 VTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPP-AEVSWYQNSFPLSASERVT 308
T L V PP I + A L C A P +WY + +
Sbjct: 61 HTT-HLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLK 119
Query: 309 MSARGS-NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPAR-FTSPPLARAP 366
+ R + TL+I V+PED G Y+CV NSLGR+ PAR PP+ P
Sbjct: 120 LRVRILIDGTLIIFRVKPEDSGKYTCVPSNSLGRSPSASAYLTVQYPARVLNMPPVIYVP 179
Query: 367 ---HSYTLSFAVDSYPP 380
H Y + VD+ PP
Sbjct: 180 VGIHGY-IRCPVDAEPP 195
Score = 35.5 bits (78), Expect = 0.44
Identities = 39/165 (23%), Positives = 66/165 (40%), Gaps = 23/165 (13%)
Query: 189 GGAAVLECRAAGNPVPTVTWHRLNDSS----SRLGEGPQLQLSRLERHHGGVYACTVDNG 244
G ++ C AAG+P P +TW ++ S S L G LQ L + G + C N
Sbjct: 277 GRELLIPCAAAGDPFPVITWRKVGKPSRSKHSALPSG-SLQFRALSKEDHGEWECVATN- 334
Query: 245 VGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTV--LADPPAEVSWYQNSFPL- 301
VVT + +TV + H R ++ T ++ P Y+ +F +
Sbjct: 335 ----VVT----SITASTHLTVIGTSPHAPGSVRVQVSMTTANVSWEPGYDGGYEQTFSVW 386
Query: 302 ------SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
+ +++ LL+ ++PE +S +A N LG
Sbjct: 387 MKRAQFGPHDWLSLPVPPGPSWLLVDTLEPETAYQFSVLAQNKLG 431
>AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell
adhesion molecule like-protein 1b protein.
Length = 1842
Score = 68.5 bits (160), Expect = 5e-11
Identities = 55/195 (28%), Positives = 75/195 (38%), Gaps = 11/195 (5%)
Query: 194 LECRAAGNPVPTVTWHR----LNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPV 249
L C A G P+P + W + L S L +S L G Y C V N G
Sbjct: 34 LPCTAPGYPIPAIRWLKDGRPLPADSRWTKRITGLTISDLRTEDSGTYICEVTNTFGSAE 93
Query: 250 VTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTM 309
T L V+ P +T+ + TG G L C + P + WY+N+ + E +
Sbjct: 94 ATGI-LMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPDEAI-- 150
Query: 310 SARG-SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFT---SPPLARA 365
S RG SN TLLI Q G Y C A A+ ++ G R S +
Sbjct: 151 SIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNP 210
Query: 366 PHSYTLSFAVDSYPP 380
++L A PP
Sbjct: 211 GEQFSLMCAAKGAPP 225
Score = 63.3 bits (147), Expect = 2e-09
Identities = 83/363 (22%), Positives = 148/363 (40%), Gaps = 21/363 (5%)
Query: 33 SFRTVVGDTLLLP-CQVQNLGSLVLLWRRAPAVLTAASLMVTRDERFRLVDGYNLQITDV 91
S R + +TLL+ Q + G+ R +++ D R+V ++ ++ +
Sbjct: 151 SIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNP 210
Query: 92 GPQIRYTVDVTIYENSETSVAL---AILGATGHTNVWETTRRITSEQHGNTNFRMIFQDA 148
G Q + AL I+ H T T+ H N I +D
Sbjct: 211 GEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQI-RDG 269
Query: 149 GDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
G Y C + V + + V PPS+RA R++TA G ++ CR G P ++
Sbjct: 270 GVYRCTARNLVGSAEYQARINVRGPPSIRAM---RNITAVAGRDTLINCRVIGYPYYSIK 326
Query: 208 WHR----LNDSSSRLG-EGPQLQLSRLERHHG-GVYACTVDNGVGPPVVTEFQLQVLYPP 261
W++ L D+ ++ E L+L+ +++ G Y C+V + + V PP
Sbjct: 327 WYKDALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPP 386
Query: 262 EITVERSWVHTGEGFRAELVCTVLA-DPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
I + G + C V + D P ++W ++ + + VT+ ++ +L I
Sbjct: 387 LIQ-PFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQI 445
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR---APHSYTLSFAVDS 377
+ V + GN +C+A N+ R ++ R P RF P + + L+ +VD
Sbjct: 446 SSVSLKHNGNDTCIASNAAATVSRERQLIVRV-PPRFVVQPNNQDGIYGKAGVLNCSVDG 504
Query: 378 YPP 380
YPP
Sbjct: 505 YPP 507
Score = 59.3 bits (137), Expect = 3e-08
Identities = 57/242 (23%), Positives = 97/242 (40%), Gaps = 21/242 (8%)
Query: 128 TRRITSEQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTAR 187
T+RIT G T + +D+G Y+C++++ + + +++ P + + + +
Sbjct: 62 TKRIT----GLTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDP-LHVTLTPKKLKTG 116
Query: 188 RGGAAVLECRAAGNPVPTVTWHR-----LNDS--SSRLGEGPQLQLSRLERHHGGVYACT 240
G +L C G+P T+ W+R L D S R L ++ ++ H G Y C
Sbjct: 117 IGSTVILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCF 176
Query: 241 VDNGVGPPVVTEFQLQVLY--PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS 298
+F + L P I S G + L+C PP V+W +
Sbjct: 177 ATRKA--QTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDD 234
Query: 299 FPL--SASERV---TMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
P+ S R TMS + + + Q D G Y C A N +G A ++ R
Sbjct: 235 EPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGP 294
Query: 354 PA 355
P+
Sbjct: 295 PS 296
Score = 51.6 bits (118), Expect = 6e-06
Identities = 57/226 (25%), Positives = 87/226 (38%), Gaps = 22/226 (9%)
Query: 149 GDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
G+ C S+ A + + V VPP P + G A VL C G P P V
Sbjct: 454 GNDTCIASNAAATVSRERQLIVRVPPRFVVQPNNQD--GIYGKAGVLNCSVDGYPPPKVM 511
Query: 208 WHRLNDSSSRLGEGP-----QLQL----SRLERH----HGGVYACTVDNGVGPPVVTEFQ 254
W S + P ++Q+ S L RH G Y C NGVG +
Sbjct: 512 WKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMF 571
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASE--RVTMSAR 312
L V P IT + +G EL CT + P + W + + R ++ +
Sbjct: 572 LTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATK 631
Query: 313 -GSNHTLLIADVQPEDFGN---YSCVADNSLGRARRHVEVSGRPGP 354
+ + ++P D G+ +SC A NS G R ++++ + P
Sbjct: 632 DNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPP 677
Score = 39.5 bits (88), Expect = 0.027
Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 4/64 (6%)
Query: 279 ELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNS 338
+L CT P + W ++ PL A R T G L I+D++ ED G Y C N+
Sbjct: 33 QLPCTAPGYPIPAIRWLKDGRPLPADSRWTKRITG----LTISDLRTEDSGTYICEVTNT 88
Query: 339 LGRA 342
G A
Sbjct: 89 FGSA 92
Score = 39.5 bits (88), Expect = 0.027
Identities = 46/183 (25%), Positives = 74/183 (40%), Gaps = 18/183 (9%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARG---SNHTLLIADVQPEDFGNYSCVAD 336
L C + DP V W ++S ++ V+M +N TLL+ V+ ED G Y+C A
Sbjct: 1098 LPCNSVGDPAPAVKWTKDSE--DSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTAT 1155
Query: 337 NSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINES 396
N+ G V + + P + + S TL++ P D R + S
Sbjct: 1156 NTGGFDTIIVNLLVQVPPDQPRLTVSKTSASSITLTWI-----PGDNGGSSIRGFVLQYS 1210
Query: 397 FQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVSDIFQFH 456
W DV +++ S +L L+ Y+ + AKN G +S+I +
Sbjct: 1211 VDNSEEWKDVFISSSER--------SFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAK 1262
Query: 457 TLG 459
T G
Sbjct: 1263 THG 1265
Score = 32.7 bits (71), Expect = 3.1
Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 4/67 (5%)
Query: 146 QDAGDYVCQISDRVARD--QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
+D G Y+CQ S+ V D + + V +P + + P T A +G A L C A G
Sbjct: 549 EDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNT--TIAIKGHAKELNCTARGERP 606
Query: 204 PTVTWHR 210
+ W +
Sbjct: 607 IIIRWEK 613
>U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor
precursor protein.
Length = 1070
Score = 68.1 bits (159), Expect = 7e-11
Identities = 45/150 (30%), Positives = 59/150 (39%), Gaps = 3/150 (2%)
Query: 192 AVLECRAAGNPVPTVTWHRLNDSSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPP 248
A + C A G PT+ W R + SS L +R+ R G Y C NG
Sbjct: 520 ATVPCSATGREKPTIKWERADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQ 579
Query: 249 VVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVT 308
+ QL V VE +G A L C DP + W L ++
Sbjct: 580 IRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGP 639
Query: 309 MSARGSNHTLLIADVQPEDFGNYSCVADNS 338
N +L+I DV PED G Y+C+A NS
Sbjct: 640 RMHIFQNGSLVIHDVAPEDSGRYTCIAGNS 669
Score = 58.4 bits (135), Expect = 5e-08
Identities = 59/231 (25%), Positives = 94/231 (40%), Gaps = 16/231 (6%)
Query: 127 TTRRITSEQHGNTNFRMIFQDAGDYVCQISDRVA-RDQVHTVEVLVPPSVRASPETRHVT 185
T R+ + H + DAG Y C ++ R Q + V PS P+ +
Sbjct: 365 THGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQL- 423
Query: 186 ARRGGAAVLECRAAGNPVPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACT 240
G L+C P PTV W+R DS + + L+++ +E + G Y C
Sbjct: 424 -EEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCM 482
Query: 241 VDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGE-GFRAELVCTVLADPPAEVSWYQNSF 299
G + + ++QVL + T E A + C+ + W + +
Sbjct: 483 SSTPAG-SIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKW-ERAD 540
Query: 300 PLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNS-LGRARRHVEVS 349
S E VT +A TL A V +D GNY+C+A N G+ R HV+++
Sbjct: 541 GSSLPEWVTDNA----GTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLT 587
Score = 47.6 bits (108), Expect = 1e-04
Identities = 54/239 (22%), Positives = 89/239 (37%), Gaps = 24/239 (10%)
Query: 124 VWETTRRITSEQHGNTNFRMI--FQDAGDYVCQISDRVARDQVHTVEVLVPPS-VRASPE 180
V +T RR Q + +F + QD+G + C D V ++ + + A P
Sbjct: 72 VQDTERRFA--QGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPV 129
Query: 181 T-RHVTARRG----GAAVLECRAAGNPVPTVTWHR----LNDSSSR---LGEGPQLQLSR 228
+H + L C G+P PT W R L+D S + L L
Sbjct: 130 VLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRP 189
Query: 229 LERHHGGVYACTVDNGVGPPVVTE-FQLQVLYPP--EITVERSWVHTGEGFRAELVCTVL 285
H G+Y+C + G ++ F L + + + V A C
Sbjct: 190 AGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFS 249
Query: 286 ADPPAEVSW-YQNSFPLSASERVTMSARGS---NHTLLIADVQPEDFGNYSCVADNSLG 340
A PP + W +++ P++ R R + N +LL+ V+P + G Y C+ G
Sbjct: 250 AQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRG 308
Score = 46.4 bits (105), Expect = 2e-04
Identities = 33/138 (23%), Positives = 59/138 (42%), Gaps = 6/138 (4%)
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCT 283
L L+++ + G+Y C GPP++ E L + ++ + V T G + C
Sbjct: 286 LLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTA-GSEERVTCL 344
Query: 284 VLADPPAEVSWYQNS-FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
P W++++ L RV H L++A++ D G Y+C A N G+
Sbjct: 345 PPKGLPEPSVWWEHAGVRLPTHGRVYQKG----HELVLANIAESDAGVYTCHAANLAGQR 400
Query: 343 RRHVEVSGRPGPARFTSP 360
R+ V ++ P+ P
Sbjct: 401 RQDVNITVATVPSWLKKP 418
Score = 46.0 bits (104), Expect = 3e-04
Identities = 46/168 (27%), Positives = 64/168 (38%), Gaps = 13/168 (7%)
Query: 200 GNPVPTVTWH----RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQL 255
G P P+V W RL +G +L L+ + GVY C N G + +
Sbjct: 348 GLPEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRR-QDVNI 406
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
V P + EG L C A P V WY+N +S R + G
Sbjct: 407 TVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNG-- 464
Query: 316 HTLLIADVQPEDFGNYSCVADNSLG--RARRHVEVSGRPGPARFTSPP 361
TL I V+ D Y C++ G A+ V+V + +FT PP
Sbjct: 465 -TLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEK---LKFTPPP 508
Score = 41.5 bits (93), Expect = 0.007
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 133 SEQHGNTNF-RMIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGG 190
++ G +F R+ DAG+Y C I+ + Q+ V++ V + E T +G
Sbjct: 549 TDNAGTLHFARVTRDDAGNYTC-IASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGH 607
Query: 191 AAVLECRAAGNPVPTVTW 208
A+L+C A G+P P + W
Sbjct: 608 TALLQCEAQGDPKPLIQW 625
Score = 38.3 bits (85), Expect = 0.062
Identities = 40/169 (23%), Positives = 69/169 (40%), Gaps = 14/169 (8%)
Query: 186 ARRGGAAVLECRAAGNPVPTVTW----HRLNDSSSRLGEGPQLQLSRLER-HHGGVYACT 240
A +G A+L C V W + D+ R +G L + ++R G + C
Sbjct: 43 ALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCV 102
Query: 241 V-DNGVGPPVVT---EFQLQVLYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEVSW 294
D+ G + F ++ + + ++ S + L C + P W
Sbjct: 103 ARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQW 162
Query: 295 YQNSFPLSASE-RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+++ PLS + T+S++ N TL A PE G YSC A ++ G+A
Sbjct: 163 FRDGTPLSDGQSNHTVSSKERNLTLRPAG--PEHSGLYSCCAHSAFGQA 209
Score = 36.7 bits (81), Expect = 0.19
Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 4/77 (5%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
+G RA L C V A P V W + P+ +ER A+GS+ + D + +D G + C
Sbjct: 45 QGRRALLRCEVEAPGPVHVYWLLDGAPVQDTER--RFAQGSSLSFAAVD-RLQDSGTFQC 101
Query: 334 VA-DNSLGRARRHVEVS 349
VA D+ G R S
Sbjct: 102 VARDDVTGEEARSANAS 118
>U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4
protein.
Length = 1070
Score = 68.1 bits (159), Expect = 7e-11
Identities = 45/150 (30%), Positives = 59/150 (39%), Gaps = 3/150 (2%)
Query: 192 AVLECRAAGNPVPTVTWHRLNDSSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPP 248
A + C A G PT+ W R + SS L +R+ R G Y C NG
Sbjct: 520 ATVPCSATGREKPTIKWERADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQ 579
Query: 249 VVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVT 308
+ QL V VE +G A L C DP + W L ++
Sbjct: 580 IRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGP 639
Query: 309 MSARGSNHTLLIADVQPEDFGNYSCVADNS 338
N +L+I DV PED G Y+C+A NS
Sbjct: 640 RMHIFQNGSLVIHDVAPEDSGRYTCIAGNS 669
Score = 59.3 bits (137), Expect = 3e-08
Identities = 60/231 (25%), Positives = 94/231 (40%), Gaps = 16/231 (6%)
Query: 127 TTRRITSEQHGNTNFRMIFQDAGDYVCQISDRVA-RDQVHTVEVLVPPSVRASPETRHVT 185
T R+ + H + DAG Y C ++ R Q + V PS P+ +
Sbjct: 365 THGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQL- 423
Query: 186 ARRGGAAVLECRAAGNPVPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACT 240
G L+C P PTV W+R DS + + L+++ +E + G Y C
Sbjct: 424 -EEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCM 482
Query: 241 VDNGVGPPVVTEFQLQVLYPPEIT-VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSF 299
G + + LQVL + T + G A + C+ + W + +
Sbjct: 483 SSTPAG-SIEAQAVLQVLEKLKFTPPPQPQQCMGFDKEATVPCSATGREKPTIKW-ERAD 540
Query: 300 PLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNS-LGRARRHVEVS 349
S E VT +A TL A V +D GNY+C+A N G+ R HV+++
Sbjct: 541 GSSLPEWVTDNA----GTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLT 587
Score = 46.4 bits (105), Expect = 2e-04
Identities = 33/138 (23%), Positives = 59/138 (42%), Gaps = 6/138 (4%)
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCT 283
L L+++ + G+Y C GPP++ E L + ++ + V T G + C
Sbjct: 286 LLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTA-GSEERVTCL 344
Query: 284 VLADPPAEVSWYQNS-FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
P W++++ L RV H L++A++ D G Y+C A N G+
Sbjct: 345 PPKGLPEPSVWWEHAGVRLPTHGRVYQKG----HELVLANIAESDAGVYTCHAANLAGQR 400
Query: 343 RRHVEVSGRPGPARFTSP 360
R+ V ++ P+ P
Sbjct: 401 RQDVNITVATVPSWLKKP 418
Score = 44.4 bits (100), Expect = 0.001
Identities = 53/239 (22%), Positives = 88/239 (36%), Gaps = 24/239 (10%)
Query: 124 VWETTRRITSEQHGNTNFRMI--FQDAGDYVCQISDRVARDQVHTVEVLVPPS-VRASPE 180
V +T RR Q + +F + QD+G + C D V ++ + + A P
Sbjct: 72 VQDTERRFA--QGSSLSFAAVDPLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPV 129
Query: 181 T-RHVTARRG----GAAVLECRAAGNPVPTVTWHR----LNDSSSR---LGEGPQLQLSR 228
+H + L C G+P PT W R L+D S + L L
Sbjct: 130 VLKHPASEAEIQPQTQVKLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRP 189
Query: 229 LERHHGGVYACTVDNGVGPPVVTE-FQLQVLYPP--EITVERSWVHTGEGFRAELVCTVL 285
H G+Y+C + ++ F L + + + V A C
Sbjct: 190 AGPEHSGLYSCCAHSAFSQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFS 249
Query: 286 ADPPAEVSW-YQNSFPLSASERVTMSARGS---NHTLLIADVQPEDFGNYSCVADNSLG 340
A PP + W +++ P++ R R + N +LL+ V+P + G Y C+ G
Sbjct: 250 AQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRG 308
Score = 43.6 bits (98), Expect = 0.002
Identities = 43/166 (25%), Positives = 59/166 (35%), Gaps = 9/166 (5%)
Query: 200 GNPVPTVTWH----RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQL 255
G P P+V W RL +G +L L+ + GVY C N G + +
Sbjct: 348 GLPEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRR-QDVNI 406
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
V P + EG L C A P V WY+N +S R + G
Sbjct: 407 TVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNG-- 464
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPP 361
TL I V+ D Y C++ G + +FT PP
Sbjct: 465 -TLRINSVEVYDGTWYRCMSSTPAGSIEAQAVLQVLE-KLKFTPPP 508
Score = 41.5 bits (93), Expect = 0.007
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 133 SEQHGNTNF-RMIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGG 190
++ G +F R+ DAG+Y C I+ + Q+ V++ V + E T +G
Sbjct: 549 TDNAGTLHFARVTRDDAGNYTC-IASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGH 607
Query: 191 AAVLECRAAGNPVPTVTW 208
A+L+C A G+P P + W
Sbjct: 608 TALLQCEAQGDPKPLIQW 625
Score = 37.5 bits (83), Expect = 0.11
Identities = 29/78 (37%), Positives = 38/78 (48%), Gaps = 6/78 (7%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQP-EDFGNYS 332
+G RA L C V A P V W + P+ +ER A+GS +L A V P +D G +
Sbjct: 45 QGRRALLRCEVEAPGPVHVYWLLDGAPVQDTER--RFAQGS--SLSFAAVDPLQDSGTFQ 100
Query: 333 CVA-DNSLGRARRHVEVS 349
CVA D+ G R S
Sbjct: 101 CVARDDVTGEEARSANAS 118
Score = 33.9 bits (74), Expect = 1.3
Identities = 38/169 (22%), Positives = 68/169 (40%), Gaps = 14/169 (8%)
Query: 186 ARRGGAAVLECRAAGNPVPTVTW----HRLNDSSSRLGEGPQLQLSRLER-HHGGVYACT 240
A +G A+L C V W + D+ R +G L + ++ G + C
Sbjct: 43 ALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDPLQDSGTFQCV 102
Query: 241 V-DNGVGPPVVT---EFQLQVLYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEVSW 294
D+ G + F ++ + + ++ S + +L C + P W
Sbjct: 103 ARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVKLRCHIDGHPRPTYQW 162
Query: 295 YQNSFPLSASE-RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+++ PLS + T+S++ N TL A PE G YSC A ++ +A
Sbjct: 163 FRDGTPLSDGQSNHTVSSKERNLTLRPAG--PEHSGLYSCCAHSAFSQA 209
>EF063638-1|ABO42328.1| 1896|Homo sapiens obscurin-like 1 isoform A
protein.
Length = 1896
Score = 68.1 bits (159), Expect = 7e-11
Identities = 60/200 (30%), Positives = 93/200 (46%), Gaps = 21/200 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVT--ARRGGAAVLECRAAGNPV 203
+D+G+Y+C+I D A TV V PP VR VT A VL C +
Sbjct: 963 EDSGEYLCEIDDESAS---FTVTVTEPP-VRIIYPRDEVTLIAVTLECVVLMCELSREDA 1018
Query: 204 PTVTWHR----LNDSSSRLGE--GPQ--LQLSRLERHHGGVYACTV--DNGVGPPVVTEF 253
P V W++ + +S + + E GP+ L L + GG + C D+ VT
Sbjct: 1019 P-VRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDSAFFTVTVTAP 1077
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
++++P +++ +H G R EL C V A ++V WY++ + AS+ + + A G
Sbjct: 1078 PERIVHPAARSLD---LHFGAPGRVELRCEV-APAGSQVRWYKDGLEVEASDALQLGAEG 1133
Query: 314 SNHTLLIADVQPEDFGNYSC 333
TL + QPED G Y C
Sbjct: 1134 PTRTLTLPHAQPEDAGEYVC 1153
Score = 61.7 bits (143), Expect = 6e-09
Identities = 34/86 (39%), Positives = 43/86 (50%)
Query: 270 VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFG 329
V G AEL C VL +PP V W + L+ASER++ A G+ H LL+ P D G
Sbjct: 21 VRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAG 80
Query: 330 NYSCVADNSLGRARRHVEVSGRPGPA 355
Y C A N+ G A V+ PA
Sbjct: 81 VYVCRARNAAGEAYAAAAVTVLEPPA 106
Score = 57.2 bits (132), Expect = 1e-07
Identities = 60/208 (28%), Positives = 80/208 (38%), Gaps = 37/208 (17%)
Query: 188 RGGAAVLECRAAGNPVPTVTWHR-------LNDSS------SRLGEGP----QLQLSRLE 230
RG VL CRA G P PT+ W + + DSS R +GP L++
Sbjct: 141 RGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAAR 200
Query: 231 RHHGGVYACTVDNGVG----------------PPV-VTEFQLQVLYPPEITVERSWVHTG 273
GVY C N G PP E V+ P + + WV+
Sbjct: 201 LPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEPLKCAPKTFWVN-- 258
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA-RGSNHTLLIADVQPEDFGNYS 332
EG A+ C V+ P E+ W+ PL R M R L + Q +D G Y
Sbjct: 259 EGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYV 318
Query: 333 CVADNSLGRARRHVEVSGRPGPARFTSP 360
C A NS G+ V++ + RFT P
Sbjct: 319 CAARNSAGQTLSAVQLHVKEPRLRFTRP 346
Score = 49.2 bits (112), Expect = 3e-05
Identities = 61/230 (26%), Positives = 84/230 (36%), Gaps = 18/230 (7%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+D G++VC D A TV V PP P R + G +E R P +
Sbjct: 1054 EDGGEFVCDAGDDSA---FFTVTVTAPPERIVHPAARSLDLHFGAPGRVELRCEVAPAGS 1110
Query: 206 -VTWHR------LNDSSSRLGEGPQ--LQLSRLERHHGGVYAC-TVDNGVGPPVV-TEFQ 254
V W++ +D+ EGP L L + G Y C T + V+ E
Sbjct: 1111 QVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEYVCETRHEAITFNVILAEPP 1170
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
+Q L E T V GE L C L+ A V W N P+ E + + A G
Sbjct: 1171 VQFL-ALETTPSPLCVAPGEP--VVLSCE-LSRAGAPVVWSHNGRPVQEGEGLELHAEGP 1226
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR 364
L I P G Y+C + + G V P R +P A+
Sbjct: 1227 RRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAPEAAQ 1276
Score = 46.8 bits (106), Expect = 2e-04
Identities = 53/186 (28%), Positives = 74/186 (39%), Gaps = 17/186 (9%)
Query: 171 VPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDS---SSRL-----GEGP 222
VP ++ P VT G A EC + + VTW + ++ S RL G
Sbjct: 1627 VPVTIVRGPHDLEVT--EGDTATFECELS-QALADVTWEKDGNALTPSPRLRLQALGTRR 1683
Query: 223 QLQLSRLERHHGGVYACTVDNG-VGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELV 281
LQL R G Y+C V GP +T + V E+ RS V EG A
Sbjct: 1684 LLQLRRCGPSDAGTYSCAVGTARAGPVRLTVRERTVAVLSEL---RS-VSAREGDGATFE 1739
Query: 282 CTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGR 341
CTV ++ W PL RV + G H L++++++ ED G A +
Sbjct: 1740 CTV-SEVETTGRWELGGRPLRPGARVRIRQEGKKHILVLSELRAEDAGEVRFQAGPAQSL 1798
Query: 342 ARRHVE 347
A VE
Sbjct: 1799 ALLEVE 1804
Score = 46.4 bits (105), Expect = 2e-04
Identities = 62/213 (29%), Positives = 82/213 (38%), Gaps = 24/213 (11%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG Y C + A TV +V E R V+AR G A EC + V T
Sbjct: 1694 DAGTYSCAVGTARAGPVRLTVR---ERTVAVLSELRSVSAREGDGATFECTVS--EVETT 1748
Query: 207 TWHRLNDSSSRLG-------EGPQ--LQLSRLERHHGGV--YACTVDNGVGPPVVTEFQL 255
L R G EG + L LS L G + + V L
Sbjct: 1749 GRWELGGRPLRPGARVRIRQEGKKHILVLSELRAEDAGEVRFQAGPAQSLALLEVEALPL 1808
Query: 256 QVL-YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
Q+ +PP E++ + G RA L TV + V W + L ++ M + G
Sbjct: 1809 QMCRHPPR---EKTVL---VGRRAVLEVTV-SRSGGHVCWLREGAELCPGDKYEMRSHGP 1861
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVE 347
H+L+I DV+PED G Y C A R VE
Sbjct: 1862 THSLVIHDVRPEDQGTYCCQAGQDSTHTRLLVE 1894
Score = 44.0 bits (99), Expect = 0.001
Identities = 57/211 (27%), Positives = 84/211 (39%), Gaps = 18/211 (8%)
Query: 148 AGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARR--GGAAVLECRAAGNPVP 204
AG Y CQ + TV+V PP +PE R GG L +G P
Sbjct: 1240 AGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAPEAAQTRVRSTPGGDLELVVHLSG-PGG 1298
Query: 205 TVTWHRLND---SSSRL-----GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVT-EFQL 255
V W++ + S R+ G L++ G Y C +V+ E L
Sbjct: 1299 PVRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEYLCDAPQDSRIFLVSVEEPL 1358
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
V E+T VH G+ A C V + P A+V+W +N ++ +V M+ GS+
Sbjct: 1359 LVKLVSELTPLT--VHEGDD--ATFRCEV-SPPDADVTWLRNGAVVTPGPQVEMAQNGSS 1413
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
L + Q D G + A ++ AR HV
Sbjct: 1414 RILTLRGCQLGDAGTVTLRAGSTATSARLHV 1444
Score = 42.7 bits (96), Expect = 0.003
Identities = 52/203 (25%), Positives = 85/203 (41%), Gaps = 26/203 (12%)
Query: 147 DAGDYVCQISDRVARDQVHTVEV---LVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D G++ C D A V +V +V PS + +V A R VL C P
Sbjct: 873 DGGEFQCVAGDECAYFTVTITDVSSWIVYPSGKV-----YVAAVRLERVVLTCELC-RPW 926
Query: 204 PTVTWHR----LNDSSSRLGEGP----QLQLSRLERHHGGVYACTVDNGVGP--PVVTEF 253
V W + + +S + L + +L L ++ G Y C +D+ VTE
Sbjct: 927 AEVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDDESASFTVTVTEP 986
Query: 254 QLQVLYP-PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
++++YP E+T+ + L+C L+ A V WY++ + SE + +
Sbjct: 987 PVRIIYPRDEVTLIAVTLEC-----VVLMCE-LSREDAPVRWYKDGLEVEESEALVLERD 1040
Query: 313 GSNHTLLIADVQPEDFGNYSCVA 335
G L++ QPED G + C A
Sbjct: 1041 GPRCRLVLPAAQPEDGGEFVCDA 1063
Score = 42.3 bits (95), Expect = 0.004
Identities = 62/223 (27%), Positives = 86/223 (38%), Gaps = 21/223 (9%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG+Y+C D ++ V V P V+ E +T G A C + P V
Sbjct: 1335 DAGEYLC---DAPQDSRIFLVSVEEPLLVKLVSELTPLTVHEGDDATFRCEVSP-PDADV 1390
Query: 207 TWHRLNDSSSRLGEGPQLQL-----SRLERHHGGVY--ACTVDNGVGPPVVTEFQLQVLY 259
TW R + + + GPQ+++ SR+ G A TV G T +L V
Sbjct: 1391 TWLR---NGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAGTVTLRAGS-TATSARLHVRE 1446
Query: 260 PPEITVERSW-VHTGEGFRAEL-VCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
+ + R V EG L V T V W + PL R++M+ G H
Sbjct: 1447 TELLFLRRLQDVRAEEGQDVCLEVETGRVGAAGAVRWVRGGQPLPHDSRLSMAQDGHIHR 1506
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
L I V D G Y C + + AR +S RP R P
Sbjct: 1507 LFIHGVILADQGTYGCESHHDRTLAR----LSVRPRQLRVLRP 1545
Score = 40.7 bits (91), Expect = 0.012
Identities = 53/202 (26%), Positives = 84/202 (41%), Gaps = 20/202 (9%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVP-PSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G YVC + A + V++ V P +R + + V R G AVLEC+ + +P
Sbjct: 312 KDRGLYVCAARNS-AGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKVPNSRIP 370
Query: 205 TVTWHRLND------SSSRLGEGP--QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
T W R + ++ EG +L + RL+ G+Y C + V T +
Sbjct: 371 T-AWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCEMRGRVR----TVANVT 425
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
V P + R + EG A L+ L + E W ++ L + S+ G H
Sbjct: 426 VKGPILKRLPRK-LDVLEGENAVLLVETL-EAGVEGRWSRDGEELPV---ICQSSSGHMH 480
Query: 317 TLLIADVQPEDFGNYSCVADNS 338
L++ V ED G + NS
Sbjct: 481 ALVLPGVTREDAGEVTFSLGNS 502
Score = 37.5 bits (83), Expect = 0.11
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 1/70 (1%)
Query: 266 ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQP 325
E +VH L C V + A V WY++ + S+ V + G + L++ QP
Sbjct: 813 EHVFVHAITSECVMLACEVDRED-APVRWYKDGQEVEESDFVVLENEGPHRRLVLPATQP 871
Query: 326 EDFGNYSCVA 335
D G + CVA
Sbjct: 872 SDGGEFQCVA 881
Score = 36.7 bits (81), Expect = 0.19
Identities = 50/203 (24%), Positives = 79/203 (38%), Gaps = 20/203 (9%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASP-ETRHVTARRGGAAVLECRAAGNPVP 204
QD+G++ C+ A V V PP P E V A +L C P
Sbjct: 781 QDSGEFECRTEGVSA---FFGVTVQDPPVHIVDPREHVFVHAITSECVMLACEVDREDAP 837
Query: 205 TVTWHR----LNDSSSRL--GEGP--QLQLSRLERHHGGVYACTVDNGVG--PPVVTEFQ 254
V W++ + +S + EGP +L L + GG + C + +T+
Sbjct: 838 -VRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPSDGGEFQCVAGDECAYFTVTITDVS 896
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
++YP + +V R L C L P AEV W ++ + S + + +
Sbjct: 897 SWIVYPSG----KVYVAAVRLERVVLTCE-LCRPWAEVRWTKDGEEVVESPALLLQKEDT 951
Query: 315 NHTLLIADVQPEDFGNYSCVADN 337
L++ VQ ED G Y C D+
Sbjct: 952 VRRLVLPAVQLEDSGEYLCEIDD 974
Score = 32.7 bits (71), Expect = 3.1
Identities = 41/169 (24%), Positives = 62/169 (36%), Gaps = 14/169 (8%)
Query: 175 VRASPETRHVTARRGGAAVLECRAAGNPVPTVTWH----RLNDSSSRL-----GEGPQLQ 225
++ +P+T V G A C G P P + WH L RL G L+
Sbjct: 248 LKCAPKTFWVN--EGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLK 305
Query: 226 LSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP-EITVERSWVHTGEGFRAELVCTV 284
+ + G+Y C N G ++ QL V P T V E A L C V
Sbjct: 306 VLYCQAKDRGLYVCAARNSAG-QTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKV 364
Query: 285 LADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
+ +W++ L + G+ L+I ++ +D G Y C
Sbjct: 365 -PNSRIPTAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLC 412
Score = 32.3 bits (70), Expect = 4.1
Identities = 16/58 (27%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Query: 277 RAELVCTVL-ADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
R L C + D PA +WY++ + SE + + G H L++ + + +D G + C
Sbjct: 733 RVVLTCELSRVDFPA--TWYKDGQKVEESELLVVKMDGRKHRLILPEAKVQDSGEFEC 788
Score = 31.1 bits (67), Expect = 9.4
Identities = 30/98 (30%), Positives = 37/98 (37%), Gaps = 11/98 (11%)
Query: 172 PPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLND---SSSRL---GEGPQ-- 223
PP P R V G A L+C G P P V W + +S RL +G +
Sbjct: 11 PPCFLRFP--RPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHG 68
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP 261
L L+ GVY C N G + VL PP
Sbjct: 69 LLLTAALPTDAGVYVCRARNAAGEAYAAA-AVTVLEPP 105
>EF063637-1|ABO42327.1| 1544|Homo sapiens obscurin-like 1 isoform C
protein.
Length = 1544
Score = 68.1 bits (159), Expect = 7e-11
Identities = 60/200 (30%), Positives = 93/200 (46%), Gaps = 21/200 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVT--ARRGGAAVLECRAAGNPV 203
+D+G+Y+C+I D A TV V PP VR VT A VL C +
Sbjct: 964 EDSGEYLCEIDDESAS---FTVTVTEPP-VRIIYPRDEVTLIAVTLECVVLMCELSREDA 1019
Query: 204 PTVTWHR----LNDSSSRLGE--GPQ--LQLSRLERHHGGVYACTV--DNGVGPPVVTEF 253
P V W++ + +S + + E GP+ L L + GG + C D+ VT
Sbjct: 1020 P-VRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDSAFFTVTVTAP 1078
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
++++P +++ +H G R EL C V A ++V WY++ + AS+ + + A G
Sbjct: 1079 PERIVHPAARSLD---LHFGAPGRVELRCEV-APAGSQVRWYKDGLEVEASDALQLGAEG 1134
Query: 314 SNHTLLIADVQPEDFGNYSC 333
TL + QPED G Y C
Sbjct: 1135 PTRTLTLPHAQPEDAGEYVC 1154
Score = 61.7 bits (143), Expect = 6e-09
Identities = 34/86 (39%), Positives = 43/86 (50%)
Query: 270 VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFG 329
V G AEL C VL +PP V W + L+ASER++ A G+ H LL+ P D G
Sbjct: 21 VRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAG 80
Query: 330 NYSCVADNSLGRARRHVEVSGRPGPA 355
Y C A N+ G A V+ PA
Sbjct: 81 VYVCRARNAAGEAYAAAAVTVLEPPA 106
Score = 57.2 bits (132), Expect = 1e-07
Identities = 60/208 (28%), Positives = 80/208 (38%), Gaps = 37/208 (17%)
Query: 188 RGGAAVLECRAAGNPVPTVTWHR-------LNDSS------SRLGEGP----QLQLSRLE 230
RG VL CRA G P PT+ W + + DSS R +GP L++
Sbjct: 141 RGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAAR 200
Query: 231 RHHGGVYACTVDNGVG----------------PPV-VTEFQLQVLYPPEITVERSWVHTG 273
GVY C N G PP E V+ P + + WV+
Sbjct: 201 LPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEPLKCAPKTFWVN-- 258
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA-RGSNHTLLIADVQPEDFGNYS 332
EG A+ C V+ P E+ W+ PL R M R L + Q +D G Y
Sbjct: 259 EGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYV 318
Query: 333 CVADNSLGRARRHVEVSGRPGPARFTSP 360
C A NS G+ V++ + RFT P
Sbjct: 319 CAARNSAGQTLSAVQLHVKEPRLRFTRP 346
Score = 49.2 bits (112), Expect = 3e-05
Identities = 61/230 (26%), Positives = 84/230 (36%), Gaps = 18/230 (7%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
+D G++VC D A TV V PP P R + G +E R P +
Sbjct: 1055 EDGGEFVCDAGDDSA---FFTVTVTAPPERIVHPAARSLDLHFGAPGRVELRCEVAPAGS 1111
Query: 206 -VTWHR------LNDSSSRLGEGPQ--LQLSRLERHHGGVYAC-TVDNGVGPPVV-TEFQ 254
V W++ +D+ EGP L L + G Y C T + V+ E
Sbjct: 1112 QVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEYVCETRHEAITFNVILAEPP 1171
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
+Q L E T V GE L C L+ A V W N P+ E + + A G
Sbjct: 1172 VQFL-ALETTPSPLCVAPGEP--VVLSCE-LSRAGAPVVWSHNGRPVQEGEGLELHAEGP 1227
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR 364
L I P G Y+C + + G V P R +P A+
Sbjct: 1228 RRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAPEAAQ 1277
Score = 44.0 bits (99), Expect = 0.001
Identities = 57/211 (27%), Positives = 84/211 (39%), Gaps = 18/211 (8%)
Query: 148 AGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARR--GGAAVLECRAAGNPVP 204
AG Y CQ + TV+V PP +PE R GG L +G P
Sbjct: 1241 AGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAPEAAQTRVRSTPGGDLELVVHLSG-PGG 1299
Query: 205 TVTWHRLND---SSSRL-----GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVT-EFQL 255
V W++ + S R+ G L++ G Y C +V+ E L
Sbjct: 1300 PVRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEYLCDAPQDSRIFLVSVEEPL 1359
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
V E+T VH G+ A C V + P A+V+W +N ++ +V M+ GS+
Sbjct: 1360 LVKLVSELTPLT--VHEGDD--ATFRCEV-SPPDADVTWLRNGAVVTPGPQVEMAQNGSS 1414
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARRHV 346
L + Q D G + A ++ AR HV
Sbjct: 1415 RILTLRGCQLGDAGTVTLRAGSTATSARLHV 1445
Score = 42.7 bits (96), Expect = 0.003
Identities = 52/203 (25%), Positives = 85/203 (41%), Gaps = 26/203 (12%)
Query: 147 DAGDYVCQISDRVARDQVHTVEV---LVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D G++ C D A V +V +V PS + +V A R VL C P
Sbjct: 874 DGGEFQCVAGDECAYFTVTITDVSSWIVYPSGKV-----YVAAVRLERVVLTCELC-RPW 927
Query: 204 PTVTWHR----LNDSSSRLGEGP----QLQLSRLERHHGGVYACTVDNGVGP--PVVTEF 253
V W + + +S + L + +L L ++ G Y C +D+ VTE
Sbjct: 928 AEVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDDESASFTVTVTEP 987
Query: 254 QLQVLYP-PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
++++YP E+T+ + L+C L+ A V WY++ + SE + +
Sbjct: 988 PVRIIYPRDEVTLIAVTLEC-----VVLMCE-LSREDAPVRWYKDGLEVEESEALVLERD 1041
Query: 313 GSNHTLLIADVQPEDFGNYSCVA 335
G L++ QPED G + C A
Sbjct: 1042 GPRCRLVLPAAQPEDGGEFVCDA 1064
Score = 41.9 bits (94), Expect = 0.005
Identities = 58/209 (27%), Positives = 81/209 (38%), Gaps = 17/209 (8%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG+Y+C D ++ V V P V+ E +T G A C + P V
Sbjct: 1336 DAGEYLC---DAPQDSRIFLVSVEEPLLVKLVSELTPLTVHEGDDATFRCEVSP-PDADV 1391
Query: 207 TWHRLNDSSSRLGEGPQLQL-----SRLERHHGGVY--ACTVDNGVGPPVVTEFQLQVLY 259
TW R + + + GPQ+++ SR+ G A TV G T +L V
Sbjct: 1392 TWLR---NGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAGTVTLRAGS-TATSARLHVRE 1447
Query: 260 PPEITVERSW-VHTGEGFRAEL-VCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
+ + R V EG L V T V W + PL R++M+ G H
Sbjct: 1448 TELLFLRRLQDVRAEEGQDVCLEVETGRVGAAGAVRWVRGGQPLPHDSRLSMAQDGHIHR 1507
Query: 318 LLIADVQPEDFGNYSCVADNSLGRARRHV 346
L I V D G Y C + + AR V
Sbjct: 1508 LFIHGVILADQGTYGCESHHDRTLARLSV 1536
Score = 41.1 bits (92), Expect = 0.009
Identities = 63/256 (24%), Positives = 99/256 (38%), Gaps = 26/256 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVP-PSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G YVC + A + V++ V P +R + + V R G AVLEC+ + +P
Sbjct: 312 KDRGLYVCAARNS-AGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKVPNSRIP 370
Query: 205 TVTWHRLND------SSSRLGEGP--QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
T W R + ++ EG +L + RL+ G+Y C + V T +
Sbjct: 371 T-AWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCEMRGRVR----TVANVT 425
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
V P + R + EG A L+ L + E W ++ L + S+ G H
Sbjct: 426 VKGPILKRLPRK-LDVLEGENAVLLVETL-EAGVEGRWSRDGEELPV---ICQSSSGHMH 480
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLAR---APHSYTLSF 373
L++ V ED G + NS V+ + P PP+ H T+
Sbjct: 481 ALVLPGVTREDAGEVTFSLGNSRTTTLLRVKCGVKHSP---PGPPILAEMFKGHKNTVLL 537
Query: 374 AVDSYPPLDELRLLYR 389
P E +YR
Sbjct: 538 TWKPPEPAPETPFIYR 553
Score = 37.5 bits (83), Expect = 0.11
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 1/70 (1%)
Query: 266 ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQP 325
E +VH L C V + A V WY++ + S+ V + G + L++ QP
Sbjct: 814 EHVFVHAITSECVMLACEVDRED-APVRWYKDGQEVEESDFVVLENEGPHRRLVLPATQP 872
Query: 326 EDFGNYSCVA 335
D G + CVA
Sbjct: 873 SDGGEFQCVA 882
Score = 36.7 bits (81), Expect = 0.19
Identities = 50/203 (24%), Positives = 79/203 (38%), Gaps = 20/203 (9%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASP-ETRHVTARRGGAAVLECRAAGNPVP 204
QD+G++ C+ A V V PP P E V A +L C P
Sbjct: 782 QDSGEFECRTEGVSA---FFGVTVQDPPVHIVDPREHVFVHAITSECVMLACEVDREDAP 838
Query: 205 TVTWHR----LNDSSSRL--GEGP--QLQLSRLERHHGGVYACTVDNGVG--PPVVTEFQ 254
V W++ + +S + EGP +L L + GG + C + +T+
Sbjct: 839 -VRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPSDGGEFQCVAGDECAYFTVTITDVS 897
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
++YP + +V R L C L P AEV W ++ + S + + +
Sbjct: 898 SWIVYPSG----KVYVAAVRLERVVLTCE-LCRPWAEVRWTKDGEEVVESPALLLQKEDT 952
Query: 315 NHTLLIADVQPEDFGNYSCVADN 337
L++ VQ ED G Y C D+
Sbjct: 953 VRRLVLPAVQLEDSGEYLCEIDD 975
Score = 32.7 bits (71), Expect = 3.1
Identities = 41/169 (24%), Positives = 62/169 (36%), Gaps = 14/169 (8%)
Query: 175 VRASPETRHVTARRGGAAVLECRAAGNPVPTVTWH----RLNDSSSRL-----GEGPQLQ 225
++ +P+T V G A C G P P + WH L RL G L+
Sbjct: 248 LKCAPKTFWVN--EGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLK 305
Query: 226 LSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP-EITVERSWVHTGEGFRAELVCTV 284
+ + G+Y C N G ++ QL V P T V E A L C V
Sbjct: 306 VLYCQAKDRGLYVCAARNSAG-QTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKV 364
Query: 285 LADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
+ +W++ L + G+ L+I ++ +D G Y C
Sbjct: 365 -PNSRIPTAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLC 412
Score = 32.3 bits (70), Expect = 4.1
Identities = 16/58 (27%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Query: 277 RAELVCTVL-ADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
R L C + D PA +WY++ + SE + + G H L++ + + +D G + C
Sbjct: 734 RVVLTCELSRVDFPA--TWYKDGQKVEESELLVVKMDGRKHRLILPEAKVQDSGEFEC 789
Score = 31.1 bits (67), Expect = 9.4
Identities = 30/98 (30%), Positives = 37/98 (37%), Gaps = 11/98 (11%)
Query: 172 PPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLND---SSSRL---GEGPQ-- 223
PP P R V G A L+C G P P V W + +S RL +G +
Sbjct: 11 PPCFLRFP--RPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHG 68
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP 261
L L+ GVY C N G + VL PP
Sbjct: 69 LLLTAALPTDAGVYVCRARNAAGEAYAAA-AVTVLEPP 105
>BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine
kinase 7 protein.
Length = 1070
Score = 68.1 bits (159), Expect = 7e-11
Identities = 45/150 (30%), Positives = 59/150 (39%), Gaps = 3/150 (2%)
Query: 192 AVLECRAAGNPVPTVTWHRLNDSSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPP 248
A + C A G PT+ W R + SS L +R+ R G Y C NG
Sbjct: 520 ATVPCSATGREKPTIKWERADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQ 579
Query: 249 VVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVT 308
+ QL V VE +G A L C DP + W L ++
Sbjct: 580 IRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGP 639
Query: 309 MSARGSNHTLLIADVQPEDFGNYSCVADNS 338
N +L+I DV PED G Y+C+A NS
Sbjct: 640 RMHIFQNGSLVIHDVAPEDSGRYTCIAGNS 669
Score = 58.4 bits (135), Expect = 5e-08
Identities = 59/231 (25%), Positives = 94/231 (40%), Gaps = 16/231 (6%)
Query: 127 TTRRITSEQHGNTNFRMIFQDAGDYVCQISDRVA-RDQVHTVEVLVPPSVRASPETRHVT 185
T R+ + H + DAG Y C ++ R Q + V PS P+ +
Sbjct: 365 THGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQL- 423
Query: 186 ARRGGAAVLECRAAGNPVPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACT 240
G L+C P PTV W+R DS + + L+++ +E + G Y C
Sbjct: 424 -EEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCM 482
Query: 241 VDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGE-GFRAELVCTVLADPPAEVSWYQNSF 299
G + + ++QVL + T E A + C+ + W + +
Sbjct: 483 SSTPAG-SIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKW-ERAD 540
Query: 300 PLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNS-LGRARRHVEVS 349
S E VT +A TL A V +D GNY+C+A N G+ R HV+++
Sbjct: 541 GSSLPEWVTDNA----GTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLT 587
Score = 46.4 bits (105), Expect = 2e-04
Identities = 48/215 (22%), Positives = 79/215 (36%), Gaps = 20/215 (9%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPS-VRASPET-RHVTARRG----GAAVLECRAA 199
QD+G + C D V ++ + + A P +H + L C
Sbjct: 94 QDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHID 153
Query: 200 GNPVPTVTWHR----LNDSSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
G+P PT W R L+D S + L L H G+Y+C + G ++
Sbjct: 154 GHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQ 213
Query: 253 -FQLQVLYPP--EITVERSWVHTGEGFRAELVCTVLADPPAEVSW-YQNSFPLSASERVT 308
F L + + + V A C A PP + W +++ P++ R
Sbjct: 214 NFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPP 273
Query: 309 MSARGS---NHTLLIADVQPEDFGNYSCVADNSLG 340
R + N +LL+ V+P + G Y C+ G
Sbjct: 274 HLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRG 308
Score = 46.4 bits (105), Expect = 2e-04
Identities = 33/138 (23%), Positives = 59/138 (42%), Gaps = 6/138 (4%)
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCT 283
L L+++ + G+Y C GPP++ E L + ++ + V T G + C
Sbjct: 286 LLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTA-GSEERVTCL 344
Query: 284 VLADPPAEVSWYQNS-FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
P W++++ L RV H L++A++ D G Y+C A N G+
Sbjct: 345 PPKGLPEPSVWWEHAGVRLPTHGRVYQKG----HELVLANIAESDAGVYTCHAANLAGQR 400
Query: 343 RRHVEVSGRPGPARFTSP 360
R+ V ++ P+ P
Sbjct: 401 RQDVNITVATVPSWLKKP 418
Score = 46.0 bits (104), Expect = 3e-04
Identities = 46/168 (27%), Positives = 64/168 (38%), Gaps = 13/168 (7%)
Query: 200 GNPVPTVTWH----RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQL 255
G P P+V W RL +G +L L+ + GVY C N G + +
Sbjct: 348 GLPEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRR-QDVNI 406
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
V P + EG L C A P V WY+N +S R + G
Sbjct: 407 TVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNG-- 464
Query: 316 HTLLIADVQPEDFGNYSCVADNSLG--RARRHVEVSGRPGPARFTSPP 361
TL I V+ D Y C++ G A+ V+V + +FT PP
Sbjct: 465 -TLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEK---LKFTPPP 508
Score = 41.5 bits (93), Expect = 0.007
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 133 SEQHGNTNF-RMIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGG 190
++ G +F R+ DAG+Y C I+ + Q+ V++ V + E T +G
Sbjct: 549 TDNAGTLHFARVTRDDAGNYTC-IASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGH 607
Query: 191 AAVLECRAAGNPVPTVTW 208
A+L+C A G+P P + W
Sbjct: 608 TALLQCEAQGDPKPLIQW 625
Score = 40.7 bits (91), Expect = 0.012
Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 4/77 (5%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
+G RA L C V A P V W + P+ +ER A+GS+ + D +P+D G + C
Sbjct: 45 QGRRALLRCEVEAPGPVHVYWLLDGAPVQDTER--RFAQGSSLSFAAVD-RPQDSGTFQC 101
Query: 334 VA-DNSLGRARRHVEVS 349
VA D+ G R S
Sbjct: 102 VARDDVTGEEARSANAS 118
Score = 38.3 bits (85), Expect = 0.062
Identities = 40/169 (23%), Positives = 69/169 (40%), Gaps = 14/169 (8%)
Query: 186 ARRGGAAVLECRAAGNPVPTVTW----HRLNDSSSRLGEGPQLQLSRLER-HHGGVYACT 240
A +G A+L C V W + D+ R +G L + ++R G + C
Sbjct: 43 ALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRPQDSGTFQCV 102
Query: 241 V-DNGVGPPVVT---EFQLQVLYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEVSW 294
D+ G + F ++ + + ++ S + L C + P W
Sbjct: 103 ARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQW 162
Query: 295 YQNSFPLSASE-RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+++ PLS + T+S++ N TL A PE G YSC A ++ G+A
Sbjct: 163 FRDGTPLSDGQSNHTVSSKERNLTLRPAG--PEHSGLYSCCAHSAFGQA 209
>BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein.
Length = 772
Score = 68.1 bits (159), Expect = 7e-11
Identities = 81/279 (29%), Positives = 112/279 (40%), Gaps = 23/279 (8%)
Query: 183 HVTARRGGAAVLECRAAGNPVPTVTWHR------LNDSSSRLGEGPQLQLSRLERHHGGV 236
+V A G AVLE +G P P+ TW R L L G L +S + G+
Sbjct: 182 NVVAIEGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGM 241
Query: 237 YACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ 296
Y C V + +L VL PP S ++ E E CTV P V+W +
Sbjct: 242 YTCVVTYK-NENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMK 300
Query: 297 NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPAR 356
N + S+ + GSN L I V D G Y CVA+N G A+ ++ P PA
Sbjct: 301 NGDVVIPSDYFQI-VGGSN--LRILGVVKSDEGFYQCVAENEAGNAQTSAQLI-VPKPAI 356
Query: 357 FTSPPLARAPHS-----YTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAAP 411
+S L AP + F S+ P E + + + S + R + P
Sbjct: 357 PSSSVLPSAPRDVVPVLVSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDNRERALNTTQP 416
Query: 412 AAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
GSL V + L+P A+Y V A N +G E S
Sbjct: 417 ---GSLQLTVGN----LKPEAMYTFRVVAYNEWGPGESS 448
Score = 66.5 bits (155), Expect = 2e-10
Identities = 59/203 (29%), Positives = 90/203 (44%), Gaps = 17/203 (8%)
Query: 147 DAGDYVCQISDRVARDQV-HTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y C+ S + + T +V V +R +T VTA G +L+C G P+PT
Sbjct: 45 DEGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPT 104
Query: 206 VTWHRLND------SSSRLGEGPQ--LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
+ W + SR+ P LQ+SRL+ G+Y C+ N E ++++
Sbjct: 105 IHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRI 164
Query: 258 LYPPEI-----TVER-SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA 311
L P + ++R S V EG A L V PP +W + + +
Sbjct: 165 LSDPGLHRQLYFLQRPSNVVAIEGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSKKYSLL 224
Query: 312 RGSNHTLLIADVQPEDFGNYSCV 334
GSN LLI++V +D G Y+CV
Sbjct: 225 GGSN--LLISNVTDDDSGMYTCV 245
Score = 39.9 bits (89), Expect = 0.020
Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 11/135 (8%)
Query: 211 LNDSSSRLGEGPQLQLSRLE-RHHG---GVYACTVDNGVGPPVVTEF-QLQVLYPPEITV 265
+++ +L G L + L RHH G+Y C G +++ ++ V P
Sbjct: 19 MDERKQQLSNGSLLIQNILHSRHHKPDEGLYQCEASLGDSGSIISRTAKVAVAGPLRFLS 78
Query: 266 ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS---FPLSASERVTMSARGSNHTLLIAD 322
+ V G L C V+ +P + W +N P+ RV + G+ L I+
Sbjct: 79 QTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGA---LQISR 135
Query: 323 VQPEDFGNYSCVADN 337
+QP D G Y C A N
Sbjct: 136 LQPGDIGIYRCSARN 150
Score = 31.5 bits (68), Expect = 7.1
Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 5/71 (7%)
Query: 24 GP-RFLSRGHSFRTVVGDTLLLPCQVQNLGSLVLLWRRAPAVLTAASLMVTRDERFRLVD 82
GP RFLS+ S +GDT+LL C+V + W++ LT + D R ++
Sbjct: 72 GPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTP----IPGDSRVVVLP 127
Query: 83 GYNLQITDVGP 93
LQI+ + P
Sbjct: 128 SGALQISRLQP 138
>AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine
kinase 7 protein.
Length = 1070
Score = 68.1 bits (159), Expect = 7e-11
Identities = 45/150 (30%), Positives = 59/150 (39%), Gaps = 3/150 (2%)
Query: 192 AVLECRAAGNPVPTVTWHRLNDSSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPP 248
A + C A G PT+ W R + SS L +R+ R G Y C NG
Sbjct: 520 ATVPCSATGREKPTIKWERADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQ 579
Query: 249 VVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVT 308
+ QL V VE +G A L C DP + W L ++
Sbjct: 580 IRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGP 639
Query: 309 MSARGSNHTLLIADVQPEDFGNYSCVADNS 338
N +L+I DV PED G Y+C+A NS
Sbjct: 640 RMHIFQNGSLVIHDVAPEDSGRYTCIAGNS 669
Score = 58.4 bits (135), Expect = 5e-08
Identities = 59/231 (25%), Positives = 94/231 (40%), Gaps = 16/231 (6%)
Query: 127 TTRRITSEQHGNTNFRMIFQDAGDYVCQISDRVA-RDQVHTVEVLVPPSVRASPETRHVT 185
T R+ + H + DAG Y C ++ R Q + V PS P+ +
Sbjct: 365 THGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQL- 423
Query: 186 ARRGGAAVLECRAAGNPVPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACT 240
G L+C P PTV W+R DS + + L+++ +E + G Y C
Sbjct: 424 -EEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCM 482
Query: 241 VDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGE-GFRAELVCTVLADPPAEVSWYQNSF 299
G + + ++QVL + T E A + C+ + W + +
Sbjct: 483 SSTPAG-SIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKW-ERAD 540
Query: 300 PLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNS-LGRARRHVEVS 349
S E VT +A TL A V +D GNY+C+A N G+ R HV+++
Sbjct: 541 GSSLPEWVTDNA----GTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLT 587
Score = 47.6 bits (108), Expect = 1e-04
Identities = 54/239 (22%), Positives = 89/239 (37%), Gaps = 24/239 (10%)
Query: 124 VWETTRRITSEQHGNTNFRMI--FQDAGDYVCQISDRVARDQVHTVEVLVPPS-VRASPE 180
V +T RR Q + +F + QD+G + C D V ++ + + A P
Sbjct: 72 VQDTERRFA--QGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPV 129
Query: 181 T-RHVTARRG----GAAVLECRAAGNPVPTVTWHR----LNDSSSR---LGEGPQLQLSR 228
+H + L C G+P PT W R L+D S + L L
Sbjct: 130 VLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRP 189
Query: 229 LERHHGGVYACTVDNGVGPPVVTE-FQLQVLYPP--EITVERSWVHTGEGFRAELVCTVL 285
H G+Y+C + G ++ F L + + + V A C
Sbjct: 190 AGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFS 249
Query: 286 ADPPAEVSW-YQNSFPLSASERVTMSARGS---NHTLLIADVQPEDFGNYSCVADNSLG 340
A PP + W +++ P++ R R + N +LL+ V+P + G Y C+ G
Sbjct: 250 AQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRG 308
Score = 46.4 bits (105), Expect = 2e-04
Identities = 33/138 (23%), Positives = 59/138 (42%), Gaps = 6/138 (4%)
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCT 283
L L+++ + G+Y C GPP++ E L + ++ + V T G + C
Sbjct: 286 LLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTA-GSEERVTCL 344
Query: 284 VLADPPAEVSWYQNS-FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
P W++++ L RV H L++A++ D G Y+C A N G+
Sbjct: 345 PPKGLPEPSVWWEHAGVRLPTHGRVYQKG----HELVLANIAESDAGVYTCHAANLAGQR 400
Query: 343 RRHVEVSGRPGPARFTSP 360
R+ V ++ P+ P
Sbjct: 401 RQDVNITVATVPSWLKKP 418
Score = 46.0 bits (104), Expect = 3e-04
Identities = 46/168 (27%), Positives = 64/168 (38%), Gaps = 13/168 (7%)
Query: 200 GNPVPTVTWH----RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQL 255
G P P+V W RL +G +L L+ + GVY C N G + +
Sbjct: 348 GLPEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRR-QDVNI 406
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
V P + EG L C A P V WY+N +S R + G
Sbjct: 407 TVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNG-- 464
Query: 316 HTLLIADVQPEDFGNYSCVADNSLG--RARRHVEVSGRPGPARFTSPP 361
TL I V+ D Y C++ G A+ V+V + +FT PP
Sbjct: 465 -TLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEK---LKFTPPP 508
Score = 41.5 bits (93), Expect = 0.007
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 133 SEQHGNTNF-RMIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGG 190
++ G +F R+ DAG+Y C I+ + Q+ V++ V + E T +G
Sbjct: 549 TDNAGTLHFARVTRDDAGNYTC-IASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGH 607
Query: 191 AAVLECRAAGNPVPTVTW 208
A+L+C A G+P P + W
Sbjct: 608 TALLQCEAQGDPKPLIQW 625
Score = 38.3 bits (85), Expect = 0.062
Identities = 40/169 (23%), Positives = 69/169 (40%), Gaps = 14/169 (8%)
Query: 186 ARRGGAAVLECRAAGNPVPTVTW----HRLNDSSSRLGEGPQLQLSRLER-HHGGVYACT 240
A +G A+L C V W + D+ R +G L + ++R G + C
Sbjct: 43 ALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCV 102
Query: 241 V-DNGVGPPVVT---EFQLQVLYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEVSW 294
D+ G + F ++ + + ++ S + L C + P W
Sbjct: 103 ARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQW 162
Query: 295 YQNSFPLSASE-RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+++ PLS + T+S++ N TL A PE G YSC A ++ G+A
Sbjct: 163 FRDGTPLSDGQSNHTVSSKERNLTLRPAG--PEHSGLYSCCAHSAFGQA 209
Score = 36.7 bits (81), Expect = 0.19
Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 4/77 (5%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
+G RA L C V A P V W + P+ +ER A+GS+ + D + +D G + C
Sbjct: 45 QGRRALLRCEVEAPGPVHVYWLLDGAPVQDTER--RFAQGSSLSFAAVD-RLQDSGTFQC 101
Query: 334 VA-DNSLGRARRHVEVS 349
VA D+ G R S
Sbjct: 102 VARDDVTGEEARSANAS 118
>AF531872-1|AAN04866.1| 816|Homo sapiens transmembrane receptor
precursor PTK7-5 protein.
Length = 816
Score = 68.1 bits (159), Expect = 7e-11
Identities = 45/150 (30%), Positives = 59/150 (39%), Gaps = 3/150 (2%)
Query: 192 AVLECRAAGNPVPTVTWHRLNDSSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPP 248
A + C A G PT+ W R + SS L +R+ R G Y C NG
Sbjct: 520 ATVPCSATGREKPTIKWERADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQ 579
Query: 249 VVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVT 308
+ QL V VE +G A L C DP + W L ++
Sbjct: 580 IRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGP 639
Query: 309 MSARGSNHTLLIADVQPEDFGNYSCVADNS 338
N +L+I DV PED G Y+C+A NS
Sbjct: 640 RMHIFQNGSLVIHDVAPEDSGRYTCIAGNS 669
Score = 58.4 bits (135), Expect = 5e-08
Identities = 59/231 (25%), Positives = 94/231 (40%), Gaps = 16/231 (6%)
Query: 127 TTRRITSEQHGNTNFRMIFQDAGDYVCQISDRVA-RDQVHTVEVLVPPSVRASPETRHVT 185
T R+ + H + DAG Y C ++ R Q + V PS P+ +
Sbjct: 365 THGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQL- 423
Query: 186 ARRGGAAVLECRAAGNPVPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACT 240
G L+C P PTV W+R DS + + L+++ +E + G Y C
Sbjct: 424 -EEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCM 482
Query: 241 VDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGE-GFRAELVCTVLADPPAEVSWYQNSF 299
G + + ++QVL + T E A + C+ + W + +
Sbjct: 483 SSTPAG-SIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKW-ERAD 540
Query: 300 PLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNS-LGRARRHVEVS 349
S E VT +A TL A V +D GNY+C+A N G+ R HV+++
Sbjct: 541 GSSLPEWVTDNA----GTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLT 587
Score = 47.6 bits (108), Expect = 1e-04
Identities = 54/239 (22%), Positives = 89/239 (37%), Gaps = 24/239 (10%)
Query: 124 VWETTRRITSEQHGNTNFRMI--FQDAGDYVCQISDRVARDQVHTVEVLVPPS-VRASPE 180
V +T RR Q + +F + QD+G + C D V ++ + + A P
Sbjct: 72 VQDTERRFA--QGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPV 129
Query: 181 T-RHVTARRG----GAAVLECRAAGNPVPTVTWHR----LNDSSSR---LGEGPQLQLSR 228
+H + L C G+P PT W R L+D S + L L
Sbjct: 130 VLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRP 189
Query: 229 LERHHGGVYACTVDNGVGPPVVTE-FQLQVLYPP--EITVERSWVHTGEGFRAELVCTVL 285
H G+Y+C + G ++ F L + + + V A C
Sbjct: 190 AGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFS 249
Query: 286 ADPPAEVSW-YQNSFPLSASERVTMSARGS---NHTLLIADVQPEDFGNYSCVADNSLG 340
A PP + W +++ P++ R R + N +LL+ V+P + G Y C+ G
Sbjct: 250 AQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRG 308
Score = 46.4 bits (105), Expect = 2e-04
Identities = 33/138 (23%), Positives = 59/138 (42%), Gaps = 6/138 (4%)
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCT 283
L L+++ + G+Y C GPP++ E L + ++ + V T G + C
Sbjct: 286 LLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTA-GSEERVTCL 344
Query: 284 VLADPPAEVSWYQNS-FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
P W++++ L RV H L++A++ D G Y+C A N G+
Sbjct: 345 PPKGLPEPSVWWEHAGVRLPTHGRVYQKG----HELVLANIAESDAGVYTCHAANLAGQR 400
Query: 343 RRHVEVSGRPGPARFTSP 360
R+ V ++ P+ P
Sbjct: 401 RQDVNITVATVPSWLKKP 418
Score = 46.0 bits (104), Expect = 3e-04
Identities = 46/168 (27%), Positives = 64/168 (38%), Gaps = 13/168 (7%)
Query: 200 GNPVPTVTWH----RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQL 255
G P P+V W RL +G +L L+ + GVY C N G + +
Sbjct: 348 GLPEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRR-QDVNI 406
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
V P + EG L C A P V WY+N +S R + G
Sbjct: 407 TVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNG-- 464
Query: 316 HTLLIADVQPEDFGNYSCVADNSLG--RARRHVEVSGRPGPARFTSPP 361
TL I V+ D Y C++ G A+ V+V + +FT PP
Sbjct: 465 -TLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEK---LKFTPPP 508
Score = 41.5 bits (93), Expect = 0.007
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 133 SEQHGNTNF-RMIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGG 190
++ G +F R+ DAG+Y C I+ + Q+ V++ V + E T +G
Sbjct: 549 TDNAGTLHFARVTRDDAGNYTC-IASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGH 607
Query: 191 AAVLECRAAGNPVPTVTW 208
A+L+C A G+P P + W
Sbjct: 608 TALLQCEAQGDPKPLIQW 625
Score = 38.3 bits (85), Expect = 0.062
Identities = 40/169 (23%), Positives = 69/169 (40%), Gaps = 14/169 (8%)
Query: 186 ARRGGAAVLECRAAGNPVPTVTW----HRLNDSSSRLGEGPQLQLSRLER-HHGGVYACT 240
A +G A+L C V W + D+ R +G L + ++R G + C
Sbjct: 43 ALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCV 102
Query: 241 V-DNGVGPPVVT---EFQLQVLYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEVSW 294
D+ G + F ++ + + ++ S + L C + P W
Sbjct: 103 ARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQW 162
Query: 295 YQNSFPLSASE-RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+++ PLS + T+S++ N TL A PE G YSC A ++ G+A
Sbjct: 163 FRDGTPLSDGQSNHTVSSKERNLTLRPAG--PEHSGLYSCCAHSAFGQA 209
Score = 36.7 bits (81), Expect = 0.19
Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 4/77 (5%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
+G RA L C V A P V W + P+ +ER A+GS+ + D + +D G + C
Sbjct: 45 QGRRALLRCEVEAPGPVHVYWLLDGAPVQDTER--RFAQGSSLSFAAVD-RLQDSGTFQC 101
Query: 334 VA-DNSLGRARRHVEVS 349
VA D+ G R S
Sbjct: 102 VARDDVTGEEARSANAS 118
>AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor
precursor PTK7-1 protein.
Length = 1070
Score = 68.1 bits (159), Expect = 7e-11
Identities = 45/150 (30%), Positives = 59/150 (39%), Gaps = 3/150 (2%)
Query: 192 AVLECRAAGNPVPTVTWHRLNDSSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPP 248
A + C A G PT+ W R + SS L +R+ R G Y C NG
Sbjct: 520 ATVPCSATGREKPTIKWERADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQ 579
Query: 249 VVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVT 308
+ QL V VE +G A L C DP + W L ++
Sbjct: 580 IRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGP 639
Query: 309 MSARGSNHTLLIADVQPEDFGNYSCVADNS 338
N +L+I DV PED G Y+C+A NS
Sbjct: 640 RMHIFQNGSLVIHDVAPEDSGRYTCIAGNS 669
Score = 58.4 bits (135), Expect = 5e-08
Identities = 59/231 (25%), Positives = 94/231 (40%), Gaps = 16/231 (6%)
Query: 127 TTRRITSEQHGNTNFRMIFQDAGDYVCQISDRVA-RDQVHTVEVLVPPSVRASPETRHVT 185
T R+ + H + DAG Y C ++ R Q + V PS P+ +
Sbjct: 365 THGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQL- 423
Query: 186 ARRGGAAVLECRAAGNPVPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACT 240
G L+C P PTV W+R DS + + L+++ +E + G Y C
Sbjct: 424 -EEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCM 482
Query: 241 VDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGE-GFRAELVCTVLADPPAEVSWYQNSF 299
G + + ++QVL + T E A + C+ + W + +
Sbjct: 483 SSTPAG-SIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKW-ERAD 540
Query: 300 PLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNS-LGRARRHVEVS 349
S E VT +A TL A V +D GNY+C+A N G+ R HV+++
Sbjct: 541 GSSLPEWVTDNA----GTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLT 587
Score = 47.6 bits (108), Expect = 1e-04
Identities = 54/239 (22%), Positives = 89/239 (37%), Gaps = 24/239 (10%)
Query: 124 VWETTRRITSEQHGNTNFRMI--FQDAGDYVCQISDRVARDQVHTVEVLVPPS-VRASPE 180
V +T RR Q + +F + QD+G + C D V ++ + + A P
Sbjct: 72 VQDTERRFA--QGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPV 129
Query: 181 T-RHVTARRG----GAAVLECRAAGNPVPTVTWHR----LNDSSSR---LGEGPQLQLSR 228
+H + L C G+P PT W R L+D S + L L
Sbjct: 130 VLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRP 189
Query: 229 LERHHGGVYACTVDNGVGPPVVTE-FQLQVLYPP--EITVERSWVHTGEGFRAELVCTVL 285
H G+Y+C + G ++ F L + + + V A C
Sbjct: 190 AGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFS 249
Query: 286 ADPPAEVSW-YQNSFPLSASERVTMSARGS---NHTLLIADVQPEDFGNYSCVADNSLG 340
A PP + W +++ P++ R R + N +LL+ V+P + G Y C+ G
Sbjct: 250 AQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRG 308
Score = 46.4 bits (105), Expect = 2e-04
Identities = 33/138 (23%), Positives = 59/138 (42%), Gaps = 6/138 (4%)
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCT 283
L L+++ + G+Y C GPP++ E L + ++ + V T G + C
Sbjct: 286 LLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTA-GSEERVTCL 344
Query: 284 VLADPPAEVSWYQNS-FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
P W++++ L RV H L++A++ D G Y+C A N G+
Sbjct: 345 PPKGLPEPSVWWEHAGVRLPTHGRVYQKG----HELVLANIAESDAGVYTCHAANLAGQR 400
Query: 343 RRHVEVSGRPGPARFTSP 360
R+ V ++ P+ P
Sbjct: 401 RQDVNITVATVPSWLKKP 418
Score = 46.0 bits (104), Expect = 3e-04
Identities = 46/168 (27%), Positives = 64/168 (38%), Gaps = 13/168 (7%)
Query: 200 GNPVPTVTWH----RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQL 255
G P P+V W RL +G +L L+ + GVY C N G + +
Sbjct: 348 GLPEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRR-QDVNI 406
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
V P + EG L C A P V WY+N +S R + G
Sbjct: 407 TVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNG-- 464
Query: 316 HTLLIADVQPEDFGNYSCVADNSLG--RARRHVEVSGRPGPARFTSPP 361
TL I V+ D Y C++ G A+ V+V + +FT PP
Sbjct: 465 -TLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEK---LKFTPPP 508
Score = 41.5 bits (93), Expect = 0.007
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 133 SEQHGNTNF-RMIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGG 190
++ G +F R+ DAG+Y C I+ + Q+ V++ V + E T +G
Sbjct: 549 TDNAGTLHFARVTRDDAGNYTC-IASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGH 607
Query: 191 AAVLECRAAGNPVPTVTW 208
A+L+C A G+P P + W
Sbjct: 608 TALLQCEAQGDPKPLIQW 625
Score = 38.3 bits (85), Expect = 0.062
Identities = 40/169 (23%), Positives = 69/169 (40%), Gaps = 14/169 (8%)
Query: 186 ARRGGAAVLECRAAGNPVPTVTW----HRLNDSSSRLGEGPQLQLSRLER-HHGGVYACT 240
A +G A+L C V W + D+ R +G L + ++R G + C
Sbjct: 43 ALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCV 102
Query: 241 V-DNGVGPPVVT---EFQLQVLYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEVSW 294
D+ G + F ++ + + ++ S + L C + P W
Sbjct: 103 ARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQW 162
Query: 295 YQNSFPLSASE-RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+++ PLS + T+S++ N TL A PE G YSC A ++ G+A
Sbjct: 163 FRDGTPLSDGQSNHTVSSKERNLTLRPAG--PEHSGLYSCCAHSAFGQA 209
Score = 36.7 bits (81), Expect = 0.19
Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 4/77 (5%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
+G RA L C V A P V W + P+ +ER A+GS+ + D + +D G + C
Sbjct: 45 QGRRALLRCEVEAPGPVHVYWLLDGAPVQDTER--RFAQGSSLSFAAVD-RLQDSGTFQC 101
Query: 334 VA-DNSLGRARRHVEVS 349
VA D+ G R S
Sbjct: 102 VARDDVTGEEARSANAS 118
>AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase-7
protein.
Length = 1070
Score = 68.1 bits (159), Expect = 7e-11
Identities = 45/150 (30%), Positives = 59/150 (39%), Gaps = 3/150 (2%)
Query: 192 AVLECRAAGNPVPTVTWHRLNDSSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPP 248
A + C A G PT+ W R + SS L +R+ R G Y C NG
Sbjct: 520 ATVPCSATGREKPTIKWERADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQ 579
Query: 249 VVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVT 308
+ QL V VE +G A L C DP + W L ++
Sbjct: 580 IRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGP 639
Query: 309 MSARGSNHTLLIADVQPEDFGNYSCVADNS 338
N +L+I DV PED G Y+C+A NS
Sbjct: 640 RMHIFQNGSLVIHDVAPEDSGRYTCIAGNS 669
Score = 58.4 bits (135), Expect = 5e-08
Identities = 59/231 (25%), Positives = 94/231 (40%), Gaps = 16/231 (6%)
Query: 127 TTRRITSEQHGNTNFRMIFQDAGDYVCQISDRVA-RDQVHTVEVLVPPSVRASPETRHVT 185
T R+ + H + DAG Y C ++ R Q + V PS P+ +
Sbjct: 365 THGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQL- 423
Query: 186 ARRGGAAVLECRAAGNPVPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACT 240
G L+C P PTV W+R DS + + L+++ +E + G Y C
Sbjct: 424 -EEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCM 482
Query: 241 VDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGE-GFRAELVCTVLADPPAEVSWYQNSF 299
G + + ++QVL + T E A + C+ + W + +
Sbjct: 483 SSTPAG-SIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKW-ERAD 540
Query: 300 PLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNS-LGRARRHVEVS 349
S E VT +A TL A V +D GNY+C+A N G+ R HV+++
Sbjct: 541 GSSLPEWVTDNA----GTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLT 587
Score = 47.6 bits (108), Expect = 1e-04
Identities = 54/239 (22%), Positives = 89/239 (37%), Gaps = 24/239 (10%)
Query: 124 VWETTRRITSEQHGNTNFRMI--FQDAGDYVCQISDRVARDQVHTVEVLVPPS-VRASPE 180
V +T RR Q + +F + QD+G + C D V ++ + + A P
Sbjct: 72 VQDTERRFA--QGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPV 129
Query: 181 T-RHVTARRG----GAAVLECRAAGNPVPTVTWHR----LNDSSSR---LGEGPQLQLSR 228
+H + L C G+P PT W R L+D S + L L
Sbjct: 130 VLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRP 189
Query: 229 LERHHGGVYACTVDNGVGPPVVTE-FQLQVLYPP--EITVERSWVHTGEGFRAELVCTVL 285
H G+Y+C + G ++ F L + + + V A C
Sbjct: 190 AGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFS 249
Query: 286 ADPPAEVSW-YQNSFPLSASERVTMSARGS---NHTLLIADVQPEDFGNYSCVADNSLG 340
A PP + W +++ P++ R R + N +LL+ V+P + G Y C+ G
Sbjct: 250 AQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRG 308
Score = 46.4 bits (105), Expect = 2e-04
Identities = 33/138 (23%), Positives = 59/138 (42%), Gaps = 6/138 (4%)
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCT 283
L L+++ + G+Y C GPP++ E L + ++ + V T G + C
Sbjct: 286 LLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTA-GSEERVTCL 344
Query: 284 VLADPPAEVSWYQNS-FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
P W++++ L RV H L++A++ D G Y+C A N G+
Sbjct: 345 PPKGLPEPSVWWEHAGVRLPTHGRVYQKG----HELVLANIAESDAGVYTCHAANLAGQR 400
Query: 343 RRHVEVSGRPGPARFTSP 360
R+ V ++ P+ P
Sbjct: 401 RQDVNITVATVPSWLKKP 418
Score = 46.0 bits (104), Expect = 3e-04
Identities = 46/168 (27%), Positives = 64/168 (38%), Gaps = 13/168 (7%)
Query: 200 GNPVPTVTWH----RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQL 255
G P P+V W RL +G +L L+ + GVY C N G + +
Sbjct: 348 GLPEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRR-QDVNI 406
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
V P + EG L C A P V WY+N +S R + G
Sbjct: 407 TVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNG-- 464
Query: 316 HTLLIADVQPEDFGNYSCVADNSLG--RARRHVEVSGRPGPARFTSPP 361
TL I V+ D Y C++ G A+ V+V + +FT PP
Sbjct: 465 -TLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEK---LKFTPPP 508
Score = 41.5 bits (93), Expect = 0.007
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 133 SEQHGNTNF-RMIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGG 190
++ G +F R+ DAG+Y C I+ + Q+ V++ V + E T +G
Sbjct: 549 TDNAGTLHFARVTRDDAGNYTC-IASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGH 607
Query: 191 AAVLECRAAGNPVPTVTW 208
A+L+C A G+P P + W
Sbjct: 608 TALLQCEAQGDPKPLIQW 625
Score = 38.3 bits (85), Expect = 0.062
Identities = 40/169 (23%), Positives = 69/169 (40%), Gaps = 14/169 (8%)
Query: 186 ARRGGAAVLECRAAGNPVPTVTW----HRLNDSSSRLGEGPQLQLSRLER-HHGGVYACT 240
A +G A+L C V W + D+ R +G L + ++R G + C
Sbjct: 43 ALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCV 102
Query: 241 V-DNGVGPPVVT---EFQLQVLYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEVSW 294
D+ G + F ++ + + ++ S + L C + P W
Sbjct: 103 ARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQW 162
Query: 295 YQNSFPLSASE-RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+++ PLS + T+S++ N TL A PE G YSC A ++ G+A
Sbjct: 163 FRDGTPLSDGQSNHTVSSKERNLTLRPAG--PEHSGLYSCCAHSAFGQA 209
Score = 36.7 bits (81), Expect = 0.19
Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 4/77 (5%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
+G RA L C V A P V W + P+ +ER A+GS+ + D + +D G + C
Sbjct: 45 QGRRALLRCEVEAPGPVHVYWLLDGAPVQDTER--RFAQGSSLSFAAVD-RLQDSGTFQC 101
Query: 334 VA-DNSLGRARRHVEVS 349
VA D+ G R S
Sbjct: 102 VARDDVTGEEARSANAS 118
>AB209350-1|BAD92587.1| 773|Homo sapiens PTK7 protein tyrosine
kinase 7 isoform a precursor variant protein.
Length = 773
Score = 68.1 bits (159), Expect = 7e-11
Identities = 45/150 (30%), Positives = 59/150 (39%), Gaps = 3/150 (2%)
Query: 192 AVLECRAAGNPVPTVTWHRLNDSSSR---LGEGPQLQLSRLERHHGGVYACTVDNGVGPP 248
A + C A G PT+ W R + SS L +R+ R G Y C NG
Sbjct: 560 ATVPCSATGREKPTIKWERADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQ 619
Query: 249 VVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVT 308
+ QL V VE +G A L C DP + W L ++
Sbjct: 620 IRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGP 679
Query: 309 MSARGSNHTLLIADVQPEDFGNYSCVADNS 338
N +L+I DV PED G Y+C+A NS
Sbjct: 680 RMHIFQNGSLVIHDVAPEDSGRYTCIAGNS 709
Score = 58.4 bits (135), Expect = 5e-08
Identities = 59/231 (25%), Positives = 94/231 (40%), Gaps = 16/231 (6%)
Query: 127 TTRRITSEQHGNTNFRMIFQDAGDYVCQISDRVA-RDQVHTVEVLVPPSVRASPETRHVT 185
T R+ + H + DAG Y C ++ R Q + V PS P+ +
Sbjct: 405 THGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQL- 463
Query: 186 ARRGGAAVLECRAAGNPVPTVTWHR-----LNDSSSRLGEGPQLQLSRLERHHGGVYACT 240
G L+C P PTV W+R DS + + L+++ +E + G Y C
Sbjct: 464 -EEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCM 522
Query: 241 VDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGE-GFRAELVCTVLADPPAEVSWYQNSF 299
G + + ++QVL + T E A + C+ + W + +
Sbjct: 523 SSTPAG-SIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKW-ERAD 580
Query: 300 PLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNS-LGRARRHVEVS 349
S E VT +A TL A V +D GNY+C+A N G+ R HV+++
Sbjct: 581 GSSLPEWVTDNA----GTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLT 627
Score = 47.6 bits (108), Expect = 1e-04
Identities = 54/239 (22%), Positives = 89/239 (37%), Gaps = 24/239 (10%)
Query: 124 VWETTRRITSEQHGNTNFRMI--FQDAGDYVCQISDRVARDQVHTVEVLVPPS-VRASPE 180
V +T RR Q + +F + QD+G + C D V ++ + + A P
Sbjct: 112 VQDTERRFA--QGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPV 169
Query: 181 T-RHVTARRG----GAAVLECRAAGNPVPTVTWHR----LNDSSSR---LGEGPQLQLSR 228
+H + L C G+P PT W R L+D S + L L
Sbjct: 170 VLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRP 229
Query: 229 LERHHGGVYACTVDNGVGPPVVTE-FQLQVLYPP--EITVERSWVHTGEGFRAELVCTVL 285
H G+Y+C + G ++ F L + + + V A C
Sbjct: 230 AGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFS 289
Query: 286 ADPPAEVSW-YQNSFPLSASERVTMSARGS---NHTLLIADVQPEDFGNYSCVADNSLG 340
A PP + W +++ P++ R R + N +LL+ V+P + G Y C+ G
Sbjct: 290 AQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRG 348
Score = 46.4 bits (105), Expect = 2e-04
Identities = 33/138 (23%), Positives = 59/138 (42%), Gaps = 6/138 (4%)
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCT 283
L L+++ + G+Y C GPP++ E L + ++ + V T G + C
Sbjct: 326 LLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTA-GSEERVTCL 384
Query: 284 VLADPPAEVSWYQNS-FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
P W++++ L RV H L++A++ D G Y+C A N G+
Sbjct: 385 PPKGLPEPSVWWEHAGVRLPTHGRVYQKG----HELVLANIAESDAGVYTCHAANLAGQR 440
Query: 343 RRHVEVSGRPGPARFTSP 360
R+ V ++ P+ P
Sbjct: 441 RQDVNITVATVPSWLKKP 458
Score = 46.0 bits (104), Expect = 3e-04
Identities = 46/168 (27%), Positives = 64/168 (38%), Gaps = 13/168 (7%)
Query: 200 GNPVPTVTWH----RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQL 255
G P P+V W RL +G +L L+ + GVY C N G + +
Sbjct: 388 GLPEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRR-QDVNI 446
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
V P + EG L C A P V WY+N +S R + G
Sbjct: 447 TVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNG-- 504
Query: 316 HTLLIADVQPEDFGNYSCVADNSLG--RARRHVEVSGRPGPARFTSPP 361
TL I V+ D Y C++ G A+ V+V + +FT PP
Sbjct: 505 -TLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEK---LKFTPPP 548
Score = 41.5 bits (93), Expect = 0.007
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 133 SEQHGNTNF-RMIFQDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGG 190
++ G +F R+ DAG+Y C I+ + Q+ V++ V + E T +G
Sbjct: 589 TDNAGTLHFARVTRDDAGNYTC-IASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGH 647
Query: 191 AAVLECRAAGNPVPTVTW 208
A+L+C A G+P P + W
Sbjct: 648 TALLQCEAQGDPKPLIQW 665
Score = 38.3 bits (85), Expect = 0.062
Identities = 40/169 (23%), Positives = 69/169 (40%), Gaps = 14/169 (8%)
Query: 186 ARRGGAAVLECRAAGNPVPTVTW----HRLNDSSSRLGEGPQLQLSRLER-HHGGVYACT 240
A +G A+L C V W + D+ R +G L + ++R G + C
Sbjct: 83 ALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCV 142
Query: 241 V-DNGVGPPVVT---EFQLQVLYPPEITVER--SWVHTGEGFRAELVCTVLADPPAEVSW 294
D+ G + F ++ + + ++ S + L C + P W
Sbjct: 143 ARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQW 202
Query: 295 YQNSFPLSASE-RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+++ PLS + T+S++ N TL A PE G YSC A ++ G+A
Sbjct: 203 FRDGTPLSDGQSNHTVSSKERNLTLRPAG--PEHSGLYSCCAHSAFGQA 249
Score = 36.7 bits (81), Expect = 0.19
Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 4/77 (5%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
+G RA L C V A P V W + P+ +ER A+GS+ + D + +D G + C
Sbjct: 85 QGRRALLRCEVEAPGPVHVYWLLDGAPVQDTER--RFAQGSSLSFAAVD-RLQDSGTFQC 141
Query: 334 VA-DNSLGRARRHVEVS 349
VA D+ G R S
Sbjct: 142 VARDDVTGEEARSANAS 158
>AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase
protein.
Length = 1463
Score = 67.7 bits (158), Expect = 9e-11
Identities = 56/194 (28%), Positives = 80/194 (41%), Gaps = 11/194 (5%)
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN----DSSSRLGEGPQLQLSR 228
PS P+ V G + LEC A G+P P +TW R N D S + L L
Sbjct: 330 PSFVIQPQDTEVLI--GTSTTLECMATGHPHPLITWTRDNGLELDGSRHVATSSGLYLQN 387
Query: 229 LERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADP 288
+ + G + C +N G V + V PP+ TV E E +C +P
Sbjct: 388 ITQRDHGRFTCHANNSHGT-VQAAANIIVQAPPQFTVTPKDQVVLEEHAVEWLCEADGNP 446
Query: 289 PAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
P + W + L + T+ + G TL I D G Y C A +SLG + V++
Sbjct: 447 PPVIVWTKTGGQLPVEGQHTVLSSG---TLRIDRAAQHDQGQYECQAVSSLGVKKVSVQL 503
Query: 349 SGRP-GPARFTSPP 361
+ +P A FT P
Sbjct: 504 TVKPKALAVFTQLP 517
Score = 55.2 bits (127), Expect = 5e-07
Identities = 51/207 (24%), Positives = 77/207 (37%), Gaps = 17/207 (8%)
Query: 166 TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW----HRLN-DSSSRLG- 219
TVE S R + E + V G CRA GNP P + W H L+ + +RL
Sbjct: 225 TVEEFNCQSPRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNV 284
Query: 220 -EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ---VLYPPEITVERSWVHTGEG 275
+ L + GVY C N G L+ + P ++ G
Sbjct: 285 FDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVIQPQDTEVLIG 344
Query: 276 FRAELVCTVLADPPAEVSWYQ-NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCV 334
L C P ++W + N L S V S+ L + ++ D G ++C
Sbjct: 345 TSTTLECMATGHPHPLITWTRDNGLELDGSRHVATSS-----GLYLQNITQRDHGRFTCH 399
Query: 335 ADNSLGRARRHVEVSGRPGPARFTSPP 361
A+NS G + + + P +FT P
Sbjct: 400 ANNSHGTVQAAANIIVQ-APPQFTVTP 425
Score = 53.2 bits (122), Expect = 2e-06
Identities = 52/208 (25%), Positives = 82/208 (39%), Gaps = 20/208 (9%)
Query: 146 QDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G + C ++ Q + V PP +P+ + V A C A GNP P
Sbjct: 391 RDHGRFTCHANNSHGTVQAAANIIVQAPPQFTVTPKDQVVLEEH--AVEWLCEADGNPPP 448
Query: 205 TVTWHRLNDSSSRLGE-----GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+ W + G+ L++ R +H G Y C + +G V+ QL V
Sbjct: 449 VIVWTKTGGQLPVEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLGVKKVS-VQLTVK- 506
Query: 260 PPEITV-----ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
P + V + + V G+ + C +P ++W + ++ S + + G
Sbjct: 507 PKALAVFTQLPQDTSVEVGKNIN--ISCHAQGEPQPIITWNKEGVQITESGKFHVDDEG- 563
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRA 342
TL I D D G Y CVA NS G A
Sbjct: 564 --TLTIYDAGFPDQGRYECVARNSFGLA 589
>BC045734-1|AAH45734.1| 442|Homo sapiens IGSF10 protein protein.
Length = 442
Score = 67.3 bits (157), Expect = 1e-10
Identities = 66/250 (26%), Positives = 99/250 (39%), Gaps = 22/250 (8%)
Query: 130 RITSEQHGNTNFRMI-FQDAGDYVC----QISDRVARDQVHTVEVLVPPSVRASPETRHV 184
RIT ++G R + D+ D++C + + V Q+ +E+L P+ R +P +
Sbjct: 108 RITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFR-NPFNEKI 166
Query: 185 TARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQ-----------LSRLERHH 233
A+ G + L C GNP P + W + + +R GPQ +S+ R
Sbjct: 167 VAQLGKSTALNCSVDGNPPPEIIW--ILPNGTRFSNGPQSYQYLIASNGSFIISKTTRED 224
Query: 234 GGVYACTVDNGVGPPVVTEFQLQVLYPPEI-TVERSWVHTGEGFRAELVCTVLADPPAEV 292
G Y C N VG + L++ P I T V G L C P +
Sbjct: 225 AGKYRCAARNKVGY-IEKLVILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNI 283
Query: 293 SWYQNS-FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR 351
W S + + + N TL+I + D GNY C A NS+G V V
Sbjct: 284 KWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIV 343
Query: 352 PGPARFTSPP 361
P R T+ P
Sbjct: 344 AYPPRITNRP 353
Score = 52.0 bits (119), Expect = 5e-06
Identities = 60/245 (24%), Positives = 96/245 (39%), Gaps = 23/245 (9%)
Query: 130 RITSEQHGNTNFRMI-FQDAGDYVCQISDRVARD-QVHTVEVLV-PPSVRASPETRHV-- 184
R T +G+ + D+G+YVC + D +++ ++V+ PP + R V
Sbjct: 8 RYTFHANGSLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLINGLYTNRTVIK 67
Query: 185 -TARRGGAAVLECRAAGNPVPTVTWHRLND---------SSSRLGEGPQLQLSRLERHHG 234
TA R +CRA G P P V W ++ S + + L++ +
Sbjct: 68 ATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDS 127
Query: 235 GVYACTVDNGVGPPVVTEFQLQVL----YPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
+ C N G V+ QL+VL P + G L C+V +PP
Sbjct: 128 ADFICVARNEGGESVLV-VQLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPP 186
Query: 291 EVSW-YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHV--E 347
E+ W N S + SN + +I+ ED G Y C A N +G + V E
Sbjct: 187 EIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILE 246
Query: 348 VSGRP 352
+ +P
Sbjct: 247 IGQKP 251
Score = 47.2 bits (107), Expect = 1e-04
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 18/127 (14%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLV---PPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D G+Y+C+ + V + TV V++ PP + P R + R G A L C A G P
Sbjct: 319 DRGNYICKAQNSVGHTLI-TVPVMIVAYPPRITNRPP-RSIVTRTGAAFQLHCVALGVPK 376
Query: 204 PTVTW----HRLNDSSS--RLGEGPQLQL------SRLERHHGGVYACTVDNGVGPPVVT 251
P +TW H L ++S R QL L + G+Y CT N +G
Sbjct: 377 PEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDYAA 436
Query: 252 EFQLQVL 258
+ +QV+
Sbjct: 437 TY-IQVI 442
>BC031063-1|AAH31063.1| 602|Homo sapiens IGSF10 protein protein.
Length = 602
Score = 67.3 bits (157), Expect = 1e-10
Identities = 66/250 (26%), Positives = 99/250 (39%), Gaps = 22/250 (8%)
Query: 130 RITSEQHGNTNFRMI-FQDAGDYVC----QISDRVARDQVHTVEVLVPPSVRASPETRHV 184
RIT ++G R + D+ D++C + + V Q+ +E+L P+ R +P +
Sbjct: 268 RITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFR-NPFNEKI 326
Query: 185 TARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQ-----------LSRLERHH 233
A+ G + L C GNP P + W + + +R GPQ +S+ R
Sbjct: 327 VAQLGKSTALNCSVDGNPPPEIIW--ILPNGTRFSNGPQSYQYLIASNGSFIISKTTRED 384
Query: 234 GGVYACTVDNGVGPPVVTEFQLQVLYPPEI-TVERSWVHTGEGFRAELVCTVLADPPAEV 292
G Y C N VG + L++ P I T V G L C P +
Sbjct: 385 AGKYRCAARNKVGY-IEKLVILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNI 443
Query: 293 SWYQNS-FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR 351
W S + + + N TL+I + D GNY C A NS+G V V
Sbjct: 444 KWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIV 503
Query: 352 PGPARFTSPP 361
P R T+ P
Sbjct: 504 AYPPRITNRP 513
Score = 60.5 bits (140), Expect = 1e-08
Identities = 69/283 (24%), Positives = 113/283 (39%), Gaps = 25/283 (8%)
Query: 128 TRRITSEQHGNTNFRMI-FQDAGDYVCQISDRVARDQ--VHTVEVLVPPSVRASPETRHV 184
TRR T +G F + + GDY C + + +D+ VH + P +R S +T
Sbjct: 72 TRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTVITAAPRIRQSNKTNK- 130
Query: 185 TARRGGAAVLECRAAGNPVPTVTW-HRLNDSSS------RLGEGPQLQLSRLERHHGGVY 237
+ G AVL+C G+P P + W ND S L +++++ G Y
Sbjct: 131 RIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVKLLDSGEY 190
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEIT----VERSWVHTG--EGFRAELVCTVLADPPAE 291
C N G ++L V+ P + R+ + + C P E
Sbjct: 191 VCVARNPSGDD-TKMYKLDVVSKPPLINGLYTSRTVIKATAVRHSKKHFDCRAEGTPSPE 249
Query: 292 VSWYQ-NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA-----RRH 345
V W ++ L+A + N TL I +V+ D ++ CVA N G +
Sbjct: 250 VMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEV 309
Query: 346 VEVSGRPGPAR-FTSPPLARAPHSYTLSFAVDSYPPLDELRLL 387
+E+ RP F +A+ S L+ +VD PP + + +L
Sbjct: 310 LEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWIL 352
Score = 47.2 bits (107), Expect = 1e-04
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 18/127 (14%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLV---PPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D G+Y+C+ + V + TV V++ PP + P R + R G A L C A G P
Sbjct: 479 DRGNYICKAQNSVGHTLI-TVPVMIVAYPPRITNRPP-RSIVTRTGAAFQLHCVALGVPK 536
Query: 204 PTVTW----HRLNDSSS--RLGEGPQLQL------SRLERHHGGVYACTVDNGVGPPVVT 251
P +TW H L ++S R QL L + G+Y CT N +G
Sbjct: 537 PEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDYAA 596
Query: 252 EFQLQVL 258
+ +QV+
Sbjct: 597 TY-IQVI 602
>AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down
syndrome cell adhesion molecule protein.
Length = 812
Score = 67.3 bits (157), Expect = 1e-10
Identities = 64/221 (28%), Positives = 98/221 (44%), Gaps = 23/221 (10%)
Query: 130 RITSEQHGNTNF-RMIFQDAGDYVCQI-SDRV-ARDQVHTVEVLVPPSVRASPETRHVTA 186
RIT H N M+ D G Y C + D++ A+D V V P + ++ + V+
Sbjct: 191 RITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVSP 250
Query: 187 RRGGAAVLECRAAGNPVPTVTW------------HRLNDSSSRLGE-GPQLQLSRLERHH 233
L C G P+PT+TW HR++ + G L +S +
Sbjct: 251 AE--PVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRD 308
Query: 234 GGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS 293
GGVY CT +N G V+ + ++ V P I ++ + G + C V+ P +
Sbjct: 309 GGVYRCTANNSAG-VVLYQARINVRGPASIRPMKN-ITAIAGRDTYIHCRVIGYPYYSIK 366
Query: 294 WYQNSFPLSASERVTMSARGSNHTLLIADVQPE-DFGNYSC 333
WY+NS L + R A +N TL ++DVQ E D G Y+C
Sbjct: 367 WYKNSNLLPFNHR--QVAFENNGTLKLSDVQKEVDEGEYTC 405
Score = 66.9 bits (156), Expect = 2e-10
Identities = 64/225 (28%), Positives = 85/225 (37%), Gaps = 22/225 (9%)
Query: 149 GDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
G+Y C + A + + V VPP P R G A +L C A G PVPT+
Sbjct: 495 GNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP--RDQDGIYGKAVILNCSAEGYPVPTIV 552
Query: 208 WH-------------RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
W LN L G L + + G Y C V N VG V
Sbjct: 553 WKFSKGAGVPQFQPIALNGRIQVLSNG-SLLIKHVVEEDSGYYLCKVSNDVGADVSKSMY 611
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS---FPLSASERVTMSA 311
L V P IT + +G + E+ CT + P V W + P A V+
Sbjct: 612 LTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKE 671
Query: 312 RGSN--HTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
G TL I ED G +SC A NS G R ++++ + P
Sbjct: 672 VGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPP 716
Score = 63.7 bits (148), Expect = 1e-09
Identities = 52/182 (28%), Positives = 76/182 (41%), Gaps = 8/182 (4%)
Query: 183 HVTARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRLGEGPQ-LQLSRLERHHGGVYA 238
H A G L C+A G+P P W + N + S R + L + + G Y
Sbjct: 63 HRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENIRPSDSGSYV 122
Query: 239 CTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS 298
C V N G V +L V P + T+ V + G + L C+V E+SWY+N
Sbjct: 123 CEVSNRYGTAKVIG-RLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNG 181
Query: 299 FPLSASERVTMSARGSNHTLLIAD-VQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF 357
L+ + V ++ G NH LI D + D G Y C A+ +V+V G +
Sbjct: 182 EILNPGKNVRIT--GINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKI 239
Query: 358 TS 359
S
Sbjct: 240 IS 241
Score = 52.8 bits (121), Expect = 3e-06
Identities = 55/224 (24%), Positives = 89/224 (39%), Gaps = 20/224 (8%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+G YVC++S+R +V + V ++A+ R V + G L C G +
Sbjct: 117 DSGSYVCEVSNRYGTAKV-IGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQEL 175
Query: 207 TWHR----LNDSSSRLGEG---PQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+W+R LN + G L + + + GG Y C V + + +QV+
Sbjct: 176 SWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRK---DKLSAQDYVQVVL 232
Query: 260 ---PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL--SASERVTMSARGS 314
P+I S L+C V P ++W + P+ S R++
Sbjct: 233 EDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSE 292
Query: 315 NHT---LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
+ L I+ Q D G Y C A+NS G ++ R GPA
Sbjct: 293 GNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVR-GPA 335
Score = 51.2 bits (117), Expect = 8e-06
Identities = 51/225 (22%), Positives = 88/225 (39%), Gaps = 15/225 (6%)
Query: 146 QDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G Y C ++ + V P S+R +++TA G + CR G P
Sbjct: 307 RDGGVYRCTANNSAGVVLYQARINVRGPASIRPM---KNITAIAGRDTYIHCRVIGYPYY 363
Query: 205 TVTWHR------LNDSSSRLGEGPQLQLSRLERH-HGGVYACTVDNGVGPPVVTEFQLQV 257
++ W++ N L+LS +++ G Y C V V P + T + V
Sbjct: 364 SIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVL--VQPQLSTSQSVHV 421
Query: 258 LYP-PEITVERSWVHTGEGFRAELVCTVLA-DPPAEVSWYQNSFPLSASERVTMSARGSN 315
P + G R + C V++ D P ++W ++ P+ S VT+
Sbjct: 422 TVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFT 481
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
+L I+++ GNY+C+A N ++ R P P
Sbjct: 482 SSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP 526
Score = 33.1 bits (72), Expect = 2.3
Identities = 34/135 (25%), Positives = 57/135 (42%), Gaps = 18/135 (13%)
Query: 143 MIFQDAGDYVCQISDRVARDQVHT--VEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ +D+G Y+C++S+ V D + + V +P + + P T A +G + C A G
Sbjct: 586 VVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNT--TLATQGQKKEMSCTAHG 643
Query: 201 NPVPTVTWHR----LND-------SSSRLGEG--PQLQLSRLERHHGGVYACTVDNGVGP 247
V W + +N S+ +GE LQ+ R G ++C N G
Sbjct: 644 EKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGE 703
Query: 248 PVVTEFQLQVLYPPE 262
QL V PP+
Sbjct: 704 DRGI-IQLTVQEPPD 717
>AK098838-1|BAC05429.1| 399|Homo sapiens protein ( Homo sapiens
cDNA FLJ25972 fis, clone TST05664. ).
Length = 399
Score = 67.3 bits (157), Expect = 1e-10
Identities = 66/250 (26%), Positives = 99/250 (39%), Gaps = 22/250 (8%)
Query: 130 RITSEQHGNTNFRMI-FQDAGDYVC----QISDRVARDQVHTVEVLVPPSVRASPETRHV 184
RIT ++G R + D+ D++C + + V Q+ +E+L P+ R +P +
Sbjct: 65 RITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFR-NPFNEKI 123
Query: 185 TARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQ-----------LSRLERHH 233
A+ G + L C GNP P + W + + +R GPQ +S+ R
Sbjct: 124 VAQLGKSTALNCSVDGNPPPEIIW--ILPNGTRFSNGPQSYQYLIASNGSFIISKTTRED 181
Query: 234 GGVYACTVDNGVGPPVVTEFQLQVLYPPEI-TVERSWVHTGEGFRAELVCTVLADPPAEV 292
G Y C N VG + L++ P I T V G L C P +
Sbjct: 182 AGKYRCAARNKVGY-IEKLVILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNI 240
Query: 293 SWYQNS-FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR 351
W S + + + N TL+I + D GNY C A NS+G V V
Sbjct: 241 KWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIV 300
Query: 352 PGPARFTSPP 361
P R T+ P
Sbjct: 301 AYPPRITNRP 310
Score = 47.2 bits (107), Expect = 1e-04
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 18/127 (14%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLV---PPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D G+Y+C+ + V + TV V++ PP + P R + R G A L C A G P
Sbjct: 276 DRGNYICKAQNSVGHTLI-TVPVMIVAYPPRITNRPP-RSIVTRTGAAFQLHCVALGVPK 333
Query: 204 PTVTW----HRLNDSSS--RLGEGPQLQL------SRLERHHGGVYACTVDNGVGPPVVT 251
P +TW H L ++S R QL L + G+Y CT N +G
Sbjct: 334 PEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDYAA 393
Query: 252 EFQLQVL 258
+ +QV+
Sbjct: 394 TY-IQVI 399
>AK093069-1|BAC04042.1| 650|Homo sapiens protein ( Homo sapiens
cDNA FLJ35750 fis, clone TESTI2004539, weakly similar to
Homo sapiens adlican mRNA. ).
Length = 650
Score = 67.3 bits (157), Expect = 1e-10
Identities = 66/250 (26%), Positives = 99/250 (39%), Gaps = 22/250 (8%)
Query: 130 RITSEQHGNTNFRMI-FQDAGDYVC----QISDRVARDQVHTVEVLVPPSVRASPETRHV 184
RIT ++G R + D+ D++C + + V Q+ +E+L P+ R +P +
Sbjct: 316 RITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFR-NPFNEKI 374
Query: 185 TARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQ-----------LSRLERHH 233
A+ G + L C GNP P + W + + +R GPQ +S+ R
Sbjct: 375 VAQLGKSTALNCSVDGNPPPEIIW--ILPNGTRFSNGPQSYQYLIASNGSFIISKTTRED 432
Query: 234 GGVYACTVDNGVGPPVVTEFQLQVLYPPEI-TVERSWVHTGEGFRAELVCTVLADPPAEV 292
G Y C N VG + L++ P I T V G L C P +
Sbjct: 433 AGKYRCAARNKVGY-IEKLVILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNI 491
Query: 293 SWYQNS-FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR 351
W S + + + N TL+I + D GNY C A NS+G V V
Sbjct: 492 KWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIV 551
Query: 352 PGPARFTSPP 361
P R T+ P
Sbjct: 552 AYPPRITNRP 561
Score = 60.5 bits (140), Expect = 1e-08
Identities = 69/283 (24%), Positives = 113/283 (39%), Gaps = 25/283 (8%)
Query: 128 TRRITSEQHGNTNFRMI-FQDAGDYVCQISDRVARDQ--VHTVEVLVPPSVRASPETRHV 184
TRR T +G F + + GDY C + + +D+ VH + P +R S +T
Sbjct: 120 TRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTVITAAPRIRQSNKTNK- 178
Query: 185 TARRGGAAVLECRAAGNPVPTVTW-HRLNDSSS------RLGEGPQLQLSRLERHHGGVY 237
+ G AVL+C G+P P + W ND S L +++++ G Y
Sbjct: 179 RIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVKLLDSGEY 238
Query: 238 ACTVDNGVGPPVVTEFQLQVLYPPEIT----VERSWVHTG--EGFRAELVCTVLADPPAE 291
C N G ++L V+ P + R+ + + C P E
Sbjct: 239 VCVARNPSGDD-TKMYKLDVVSKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPE 297
Query: 292 VSWYQ-NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA-----RRH 345
V W ++ L+A + N TL I +V+ D ++ CVA N G +
Sbjct: 298 VMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEV 357
Query: 346 VEVSGRPGPAR-FTSPPLARAPHSYTLSFAVDSYPPLDELRLL 387
+E+ RP F +A+ S L+ +VD PP + + +L
Sbjct: 358 LEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWIL 400
Score = 47.6 bits (108), Expect = 1e-04
Identities = 52/215 (24%), Positives = 85/215 (39%), Gaps = 23/215 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D+G Y+C +++ D + V + + P+ + G ++C+A+G+PVP
Sbjct: 36 KDSGVYLCVARNKMGDDLILMHVSLRLKPAKIDHKQYFRKQVLHGKDFQVDCKASGSPVP 95
Query: 205 TVTWH-----------RLNDSSSR-----LGEGPQLQLSRLERHHGGVYACTVDNGVGPP 248
++W + +DS R L L +++ G Y C N +G
Sbjct: 96 EISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKD 155
Query: 249 VVTEFQLQVLYPPEI-TVERSWVHTGEGFRAELVCTVLADPPAEVSWY--QNSFPLSASE 305
+ + P I ++ G A L C V DP ++ W N + +
Sbjct: 156 EMKVHLTVITAAPRIRQSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSID 215
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
R T A GS L I V+ D G Y CVA N G
Sbjct: 216 RYTFHANGS---LTINKVKLLDSGEYVCVARNPSG 247
Score = 47.2 bits (107), Expect = 1e-04
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 18/127 (14%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLV---PPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
D G+Y+C+ + V + TV V++ PP + P R + R G A L C A G P
Sbjct: 527 DRGNYICKAQNSVGHTLI-TVPVMIVAYPPRITNRPP-RSIVTRTGAAFQLHCVALGVPK 584
Query: 204 PTVTW----HRLNDSSS--RLGEGPQLQL------SRLERHHGGVYACTVDNGVGPPVVT 251
P +TW H L ++S R QL L + G+Y CT N +G
Sbjct: 585 PEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDYAA 644
Query: 252 EFQLQVL 258
+ +QV+
Sbjct: 645 TY-IQVI 650
Score = 31.1 bits (67), Expect = 9.4
Identities = 21/62 (33%), Positives = 27/62 (43%)
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTLSFA 374
N +L I V +D G Y CVA N +G + VS R PA+ R + F
Sbjct: 25 NGSLFIGSVTEKDSGVYLCVARNKMGDDLILMHVSLRLKPAKIDHKQYFRKQVLHGKDFQ 84
Query: 375 VD 376
VD
Sbjct: 85 VD 86
>AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell
adhesion molecule splice variant protein.
Length = 1746
Score = 67.3 bits (157), Expect = 1e-10
Identities = 64/221 (28%), Positives = 98/221 (44%), Gaps = 23/221 (10%)
Query: 130 RITSEQHGNTNF-RMIFQDAGDYVCQI-SDRV-ARDQVHTVEVLVPPSVRASPETRHVTA 186
RIT H N M+ D G Y C + D++ A+D V V P + ++ + V+
Sbjct: 113 RITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVSP 172
Query: 187 RRGGAAVLECRAAGNPVPTVTW------------HRLNDSSSRLGE-GPQLQLSRLERHH 233
L C G P+PT+TW HR++ + G L +S +
Sbjct: 173 AE--PVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRD 230
Query: 234 GGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS 293
GGVY CT +N G V+ + ++ V P I ++ + G + C V+ P +
Sbjct: 231 GGVYRCTANNSAG-VVLYQARINVRGPASIRPMKN-ITAIAGRDTYIHCRVIGYPYYSIK 288
Query: 294 WYQNSFPLSASERVTMSARGSNHTLLIADVQPE-DFGNYSC 333
WY+NS L + R A +N TL ++DVQ E D G Y+C
Sbjct: 289 WYKNSNLLPFNHR--QVAFENNGTLKLSDVQKEVDEGEYTC 327
Score = 66.9 bits (156), Expect = 2e-10
Identities = 64/225 (28%), Positives = 85/225 (37%), Gaps = 22/225 (9%)
Query: 149 GDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
G+Y C + A + + V VPP P R G A +L C A G PVPT+
Sbjct: 417 GNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP--RDQDGIYGKAVILNCSAEGYPVPTIV 474
Query: 208 WH-------------RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
W LN L G L + + G Y C V N VG V
Sbjct: 475 WKFSKGAGVPQFQPIALNGRIQVLSNG-SLLIKHVVEEDSGYYLCKVSNDVGADVSKSMY 533
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS---FPLSASERVTMSA 311
L V P IT + +G + E+ CT + P V W + P A V+
Sbjct: 534 LTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKE 593
Query: 312 RGSN--HTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
G TL I ED G +SC A NS G R ++++ + P
Sbjct: 594 VGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPP 638
Score = 54.0 bits (124), Expect = 1e-06
Identities = 46/165 (27%), Positives = 69/165 (41%), Gaps = 8/165 (4%)
Query: 200 GNPVPTVTWHRLN---DSSSRLGEGPQ-LQLSRLERHHGGVYACTVDNGVGPPVVTEFQL 255
G+P P W + N + S R + L + + G Y C V N G V +L
Sbjct: 2 GHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIG-RL 60
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
V P + T+ V + G + L C+V E+SWY+N L+ + V ++ G N
Sbjct: 61 YVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRIT--GIN 118
Query: 316 HTLLIAD-VQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTS 359
H LI D + D G Y C A+ +V+V G + S
Sbjct: 119 HENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIIS 163
Score = 52.8 bits (121), Expect = 3e-06
Identities = 55/224 (24%), Positives = 89/224 (39%), Gaps = 20/224 (8%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+G YVC++S+R +V + V ++A+ R V + G L C G +
Sbjct: 39 DSGSYVCEVSNRYGTAKV-IGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQEL 97
Query: 207 TWHR----LNDSSSRLGEG---PQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+W+R LN + G L + + + GG Y C V + + +QV+
Sbjct: 98 SWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRK---DKLSAQDYVQVVL 154
Query: 260 ---PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL--SASERVTMSARGS 314
P+I S L+C V P ++W + P+ S R++
Sbjct: 155 EDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSE 214
Query: 315 NHT---LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
+ L I+ Q D G Y C A+NS G ++ R GPA
Sbjct: 215 GNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVR-GPA 257
Score = 51.2 bits (117), Expect = 8e-06
Identities = 51/225 (22%), Positives = 88/225 (39%), Gaps = 15/225 (6%)
Query: 146 QDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G Y C ++ + V P S+R +++TA G + CR G P
Sbjct: 229 RDGGVYRCTANNSAGVVLYQARINVRGPASIRPM---KNITAIAGRDTYIHCRVIGYPYY 285
Query: 205 TVTWHR------LNDSSSRLGEGPQLQLSRLERH-HGGVYACTVDNGVGPPVVTEFQLQV 257
++ W++ N L+LS +++ G Y C V V P + T + V
Sbjct: 286 SIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVL--VQPQLSTSQSVHV 343
Query: 258 LYP-PEITVERSWVHTGEGFRAELVCTVLA-DPPAEVSWYQNSFPLSASERVTMSARGSN 315
P + G R + C V++ D P ++W ++ P+ S VT+
Sbjct: 344 TVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFT 403
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
+L I+++ GNY+C+A N ++ R P P
Sbjct: 404 SSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP 448
Score = 44.4 bits (100), Expect = 0.001
Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 22/185 (11%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS---NHTLLIADVQPEDFGNYSCVAD 336
L C + DP V W ++S VT+ R S N + +I V+ ED G YSC+A+
Sbjct: 1057 LPCKAVGDPSPAVKWMKDSN--GTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIAN 1114
Query: 337 NSLGRAR--RHVEVSGRPGPARFTSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAIN 394
N+ G +++V P R T + S TLS+ P D R +
Sbjct: 1115 NNWGSDEIILNLQVQVPPDQPRLTVSKTTSS--SITLSWL-----PGDNGGSSIRGYILQ 1167
Query: 395 ESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVSDIFQ 454
S +W + +P+ + S+ L L+ Y+ + A+N G +S+I +
Sbjct: 1168 YSEDNSEQWGSFPI-SPSER-------SYRLENLKCGTWYKFTLTAQNGVGPGRISEIIE 1219
Query: 455 FHTLG 459
TLG
Sbjct: 1220 AKTLG 1224
Score = 38.3 bits (85), Expect = 0.062
Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 4/59 (6%)
Query: 285 LADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRAR 343
L P + W +++ PL S R + G LLI +++P D G+Y C N G A+
Sbjct: 1 LGHPEPDYRWLKDNMPLELSGRFQKTVTG----LLIENIRPSDSGSYVCEVSNRYGTAK 55
Score = 33.9 bits (74), Expect = 1.3
Identities = 42/164 (25%), Positives = 66/164 (40%), Gaps = 23/164 (14%)
Query: 163 QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLG--E 220
++ TVE L R + VT VL C+A G+P P V W + ++ + L +
Sbjct: 1026 EIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTID 1085
Query: 221 GPQLQLSR-------LERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE---ITVER--- 267
G + S ++ G Y+C +N G + LQV PP+ +TV +
Sbjct: 1086 GRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEII-LNLQVQVPPDQPRLTVSKTTS 1144
Query: 268 -----SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASER 306
SW+ G + + + S SFP+S SER
Sbjct: 1145 SSITLSWLPGDNG--GSSIRGYILQYSEDNSEQWGSFPISPSER 1186
Score = 33.1 bits (72), Expect = 2.3
Identities = 34/135 (25%), Positives = 57/135 (42%), Gaps = 18/135 (13%)
Query: 143 MIFQDAGDYVCQISDRVARDQVHT--VEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ +D+G Y+C++S+ V D + + V +P + + P T A +G + C A G
Sbjct: 508 VVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNT--TLATQGQKKEMSCTAHG 565
Query: 201 NPVPTVTWHR----LND-------SSSRLGEG--PQLQLSRLERHHGGVYACTVDNGVGP 247
V W + +N S+ +GE LQ+ R G ++C N G
Sbjct: 566 EKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGE 625
Query: 248 PVVTEFQLQVLYPPE 262
QL V PP+
Sbjct: 626 DRGI-IQLTVQEPPD 639
>AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell
adhesion molecule protein.
Length = 2012
Score = 67.3 bits (157), Expect = 1e-10
Identities = 64/221 (28%), Positives = 98/221 (44%), Gaps = 23/221 (10%)
Query: 130 RITSEQHGNTNF-RMIFQDAGDYVCQI-SDRV-ARDQVHTVEVLVPPSVRASPETRHVTA 186
RIT H N M+ D G Y C + D++ A+D V V P + ++ + V+
Sbjct: 361 RITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVSP 420
Query: 187 RRGGAAVLECRAAGNPVPTVTW------------HRLNDSSSRLGE-GPQLQLSRLERHH 233
L C G P+PT+TW HR++ + G L +S +
Sbjct: 421 AE--PVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRD 478
Query: 234 GGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS 293
GGVY CT +N G V+ + ++ V P I ++ + G + C V+ P +
Sbjct: 479 GGVYRCTANNSAG-VVLYQARINVRGPASIRPMKN-ITAIAGRDTYIHCRVIGYPYYSIK 536
Query: 294 WYQNSFPLSASERVTMSARGSNHTLLIADVQPE-DFGNYSC 333
WY+NS L + R A +N TL ++DVQ E D G Y+C
Sbjct: 537 WYKNSNLLPFNHR--QVAFENNGTLKLSDVQKEVDEGEYTC 575
Score = 66.9 bits (156), Expect = 2e-10
Identities = 64/225 (28%), Positives = 85/225 (37%), Gaps = 22/225 (9%)
Query: 149 GDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
G+Y C + A + + V VPP P R G A +L C A G PVPT+
Sbjct: 665 GNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP--RDQDGIYGKAVILNCSAEGYPVPTIV 722
Query: 208 WH-------------RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
W LN L G L + + G Y C V N VG V
Sbjct: 723 WKFSKGAGVPQFQPIALNGRIQVLSNG-SLLIKHVVEEDSGYYLCKVSNDVGADVSKSMY 781
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS---FPLSASERVTMSA 311
L V P IT + +G + E+ CT + P V W + P A V+
Sbjct: 782 LTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKE 841
Query: 312 RGSN--HTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
G TL I ED G +SC A NS G R ++++ + P
Sbjct: 842 VGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPP 886
Score = 63.7 bits (148), Expect = 1e-09
Identities = 52/182 (28%), Positives = 76/182 (41%), Gaps = 8/182 (4%)
Query: 183 HVTARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRLGEGPQ-LQLSRLERHHGGVYA 238
H A G L C+A G+P P W + N + S R + L + + G Y
Sbjct: 233 HRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENIRPSDSGSYV 292
Query: 239 CTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS 298
C V N G V +L V P + T+ V + G + L C+V E+SWY+N
Sbjct: 293 CEVSNRYGTAKVIG-RLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNG 351
Query: 299 FPLSASERVTMSARGSNHTLLIAD-VQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF 357
L+ + V ++ G NH LI D + D G Y C A+ +V+V G +
Sbjct: 352 EILNPGKNVRIT--GINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKI 409
Query: 358 TS 359
S
Sbjct: 410 IS 411
Score = 52.8 bits (121), Expect = 3e-06
Identities = 55/224 (24%), Positives = 89/224 (39%), Gaps = 20/224 (8%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+G YVC++S+R +V + V ++A+ R V + G L C G +
Sbjct: 287 DSGSYVCEVSNRYGTAKV-IGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQEL 345
Query: 207 TWHR----LNDSSSRLGEG---PQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+W+R LN + G L + + + GG Y C V + + +QV+
Sbjct: 346 SWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRK---DKLSAQDYVQVVL 402
Query: 260 ---PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL--SASERVTMSARGS 314
P+I S L+C V P ++W + P+ S R++
Sbjct: 403 EDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSE 462
Query: 315 NHT---LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
+ L I+ Q D G Y C A+NS G ++ R GPA
Sbjct: 463 GNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVR-GPA 505
Score = 51.2 bits (117), Expect = 8e-06
Identities = 51/225 (22%), Positives = 88/225 (39%), Gaps = 15/225 (6%)
Query: 146 QDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G Y C ++ + V P S+R +++TA G + CR G P
Sbjct: 477 RDGGVYRCTANNSAGVVLYQARINVRGPASIRPM---KNITAIAGRDTYIHCRVIGYPYY 533
Query: 205 TVTWHR------LNDSSSRLGEGPQLQLSRLERH-HGGVYACTVDNGVGPPVVTEFQLQV 257
++ W++ N L+LS +++ G Y C V V P + T + V
Sbjct: 534 SIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVL--VQPQLSTSQSVHV 591
Query: 258 LYP-PEITVERSWVHTGEGFRAELVCTVLA-DPPAEVSWYQNSFPLSASERVTMSARGSN 315
P + G R + C V++ D P ++W ++ P+ S VT+
Sbjct: 592 TVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFT 651
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
+L I+++ GNY+C+A N ++ R P P
Sbjct: 652 SSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP 696
Score = 44.4 bits (100), Expect = 0.001
Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 22/185 (11%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS---NHTLLIADVQPEDFGNYSCVAD 336
L C + DP V W ++S VT+ R S N + +I V+ ED G YSC+A+
Sbjct: 1305 LPCKAVGDPSPAVKWMKDSN--GTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIAN 1362
Query: 337 NSLGRAR--RHVEVSGRPGPARFTSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAIN 394
N+ G +++V P R T + S TLS+ P D R +
Sbjct: 1363 NNWGSDEIILNLQVQVPPDQPRLTVSKTTSS--SITLSWL-----PGDNGGSSIRGYILQ 1415
Query: 395 ESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVSDIFQ 454
S +W + +P+ + S+ L L+ Y+ + A+N G +S+I +
Sbjct: 1416 YSEDNSEQWGSFPI-SPSER-------SYRLENLKCGTWYKFTLTAQNGVGPGRISEIIE 1467
Query: 455 FHTLG 459
TLG
Sbjct: 1468 AKTLG 1472
Score = 33.9 bits (74), Expect = 1.3
Identities = 42/164 (25%), Positives = 66/164 (40%), Gaps = 23/164 (14%)
Query: 163 QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLG--E 220
++ TVE L R + VT VL C+A G+P P V W + ++ + L +
Sbjct: 1274 EIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTID 1333
Query: 221 GPQLQLSR-------LERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE---ITVER--- 267
G + S ++ G Y+C +N G + LQV PP+ +TV +
Sbjct: 1334 GRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEII-LNLQVQVPPDQPRLTVSKTTS 1392
Query: 268 -----SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASER 306
SW+ G + + + S SFP+S SER
Sbjct: 1393 SSITLSWLPGDNG--GSSIRGYILQYSEDNSEQWGSFPISPSER 1434
Score = 33.1 bits (72), Expect = 2.3
Identities = 34/135 (25%), Positives = 57/135 (42%), Gaps = 18/135 (13%)
Query: 143 MIFQDAGDYVCQISDRVARDQVHT--VEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ +D+G Y+C++S+ V D + + V +P + + P T A +G + C A G
Sbjct: 756 VVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNT--TLATQGQKKEMSCTAHG 813
Query: 201 NPVPTVTWHR----LND-------SSSRLGEG--PQLQLSRLERHHGGVYACTVDNGVGP 247
V W + +N S+ +GE LQ+ R G ++C N G
Sbjct: 814 EKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGE 873
Query: 248 PVVTEFQLQVLYPPE 262
QL V PP+
Sbjct: 874 DRGI-IQLTVQEPPD 887
>AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell
adhesion molecule protein.
Length = 1571
Score = 67.3 bits (157), Expect = 1e-10
Identities = 64/221 (28%), Positives = 98/221 (44%), Gaps = 23/221 (10%)
Query: 130 RITSEQHGNTNF-RMIFQDAGDYVCQI-SDRV-ARDQVHTVEVLVPPSVRASPETRHVTA 186
RIT H N M+ D G Y C + D++ A+D V V P + ++ + V+
Sbjct: 361 RITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVSP 420
Query: 187 RRGGAAVLECRAAGNPVPTVTW------------HRLNDSSSRLGE-GPQLQLSRLERHH 233
L C G P+PT+TW HR++ + G L +S +
Sbjct: 421 AE--PVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRD 478
Query: 234 GGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS 293
GGVY CT +N G V+ + ++ V P I ++ + G + C V+ P +
Sbjct: 479 GGVYRCTANNSAG-VVLYQARINVRGPASIRPMKN-ITAIAGRDTYIHCRVIGYPYYSIK 536
Query: 294 WYQNSFPLSASERVTMSARGSNHTLLIADVQPE-DFGNYSC 333
WY+NS L + R A +N TL ++DVQ E D G Y+C
Sbjct: 537 WYKNSNLLPFNHR--QVAFENNGTLKLSDVQKEVDEGEYTC 575
Score = 66.9 bits (156), Expect = 2e-10
Identities = 64/225 (28%), Positives = 85/225 (37%), Gaps = 22/225 (9%)
Query: 149 GDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
G+Y C + A + + V VPP P R G A +L C A G PVPT+
Sbjct: 665 GNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP--RDQDGIYGKAVILNCSAEGYPVPTIV 722
Query: 208 WH-------------RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
W LN L G L + + G Y C V N VG V
Sbjct: 723 WKFSKGAGVPQFQPIALNGRIQVLSNG-SLLIKHVVEEDSGYYLCKVSNDVGADVSKSMY 781
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS---FPLSASERVTMSA 311
L V P IT + +G + E+ CT + P V W + P A V+
Sbjct: 782 LTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKE 841
Query: 312 RGSN--HTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
G TL I ED G +SC A NS G R ++++ + P
Sbjct: 842 VGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPP 886
Score = 63.7 bits (148), Expect = 1e-09
Identities = 52/182 (28%), Positives = 76/182 (41%), Gaps = 8/182 (4%)
Query: 183 HVTARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRLGEGPQ-LQLSRLERHHGGVYA 238
H A G L C+A G+P P W + N + S R + L + + G Y
Sbjct: 233 HRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENIRPSDSGSYV 292
Query: 239 CTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS 298
C V N G V +L V P + T+ V + G + L C+V E+SWY+N
Sbjct: 293 CEVSNRYGTAKVIG-RLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNG 351
Query: 299 FPLSASERVTMSARGSNHTLLIAD-VQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF 357
L+ + V ++ G NH LI D + D G Y C A+ +V+V G +
Sbjct: 352 EILNPGKNVRIT--GINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKI 409
Query: 358 TS 359
S
Sbjct: 410 IS 411
Score = 52.8 bits (121), Expect = 3e-06
Identities = 55/224 (24%), Positives = 89/224 (39%), Gaps = 20/224 (8%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+G YVC++S+R +V + V ++A+ R V + G L C G +
Sbjct: 287 DSGSYVCEVSNRYGTAKV-IGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQEL 345
Query: 207 TWHR----LNDSSSRLGEG---PQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+W+R LN + G L + + + GG Y C V + + +QV+
Sbjct: 346 SWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRK---DKLSAQDYVQVVL 402
Query: 260 ---PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL--SASERVTMSARGS 314
P+I S L+C V P ++W + P+ S R++
Sbjct: 403 EDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSE 462
Query: 315 NHT---LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
+ L I+ Q D G Y C A+NS G ++ R GPA
Sbjct: 463 GNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVR-GPA 505
Score = 51.2 bits (117), Expect = 8e-06
Identities = 51/225 (22%), Positives = 88/225 (39%), Gaps = 15/225 (6%)
Query: 146 QDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G Y C ++ + V P S+R +++TA G + CR G P
Sbjct: 477 RDGGVYRCTANNSAGVVLYQARINVRGPASIRPM---KNITAIAGRDTYIHCRVIGYPYY 533
Query: 205 TVTWHR------LNDSSSRLGEGPQLQLSRLERH-HGGVYACTVDNGVGPPVVTEFQLQV 257
++ W++ N L+LS +++ G Y C V V P + T + V
Sbjct: 534 SIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVL--VQPQLSTSQSVHV 591
Query: 258 LYP-PEITVERSWVHTGEGFRAELVCTVLA-DPPAEVSWYQNSFPLSASERVTMSARGSN 315
P + G R + C V++ D P ++W ++ P+ S VT+
Sbjct: 592 TVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFT 651
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
+L I+++ GNY+C+A N ++ R P P
Sbjct: 652 SSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP 696
Score = 44.4 bits (100), Expect = 0.001
Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 22/185 (11%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS---NHTLLIADVQPEDFGNYSCVAD 336
L C + DP V W ++S VT+ R S N + +I V+ ED G YSC+A+
Sbjct: 1305 LPCKAVGDPSPAVKWMKDSN--GTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIAN 1362
Query: 337 NSLGRAR--RHVEVSGRPGPARFTSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAIN 394
N+ G +++V P R T + S TLS+ P D R +
Sbjct: 1363 NNWGSDEIILNLQVQVPPDQPRLTVSKTTSS--SITLSWL-----PGDNGGSSIRGYILQ 1415
Query: 395 ESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVSDIFQ 454
S +W + +P+ + S+ L L+ Y+ + A+N G +S+I +
Sbjct: 1416 YSEDNSEQWGSFPI-SPSER-------SYRLENLKCGTWYKFTLTAQNGVGPGRISEIIE 1467
Query: 455 FHTLG 459
TLG
Sbjct: 1468 AKTLG 1472
Score = 33.9 bits (74), Expect = 1.3
Identities = 42/164 (25%), Positives = 66/164 (40%), Gaps = 23/164 (14%)
Query: 163 QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLG--E 220
++ TVE L R + VT VL C+A G+P P V W + ++ + L +
Sbjct: 1274 EIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTID 1333
Query: 221 GPQLQLSR-------LERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE---ITVER--- 267
G + S ++ G Y+C +N G + LQV PP+ +TV +
Sbjct: 1334 GRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEII-LNLQVQVPPDQPRLTVSKTTS 1392
Query: 268 -----SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASER 306
SW+ G + + + S SFP+S SER
Sbjct: 1393 SSITLSWLPGDNG--GSSIRGYILQYSEDNSEQWGSFPISPSER 1434
Score = 33.1 bits (72), Expect = 2.3
Identities = 34/135 (25%), Positives = 57/135 (42%), Gaps = 18/135 (13%)
Query: 143 MIFQDAGDYVCQISDRVARDQVHT--VEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ +D+G Y+C++S+ V D + + V +P + + P T A +G + C A G
Sbjct: 756 VVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNT--TLATQGQKKEMSCTAHG 813
Query: 201 NPVPTVTWHR----LND-------SSSRLGEG--PQLQLSRLERHHGGVYACTVDNGVGP 247
V W + +N S+ +GE LQ+ R G ++C N G
Sbjct: 814 EKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGE 873
Query: 248 PVVTEFQLQVLYPPE 262
QL V PP+
Sbjct: 874 DRGI-IQLTVQEPPD 887
>AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell
adhesion molecule protein.
Length = 1896
Score = 67.3 bits (157), Expect = 1e-10
Identities = 64/221 (28%), Positives = 98/221 (44%), Gaps = 23/221 (10%)
Query: 130 RITSEQHGNTNF-RMIFQDAGDYVCQI-SDRV-ARDQVHTVEVLVPPSVRASPETRHVTA 186
RIT H N M+ D G Y C + D++ A+D V V P + ++ + V+
Sbjct: 347 RITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVSP 406
Query: 187 RRGGAAVLECRAAGNPVPTVTW------------HRLNDSSSRLGE-GPQLQLSRLERHH 233
L C G P+PT+TW HR++ + G L +S +
Sbjct: 407 AE--PVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRD 464
Query: 234 GGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS 293
GGVY CT +N G V+ + ++ V P I ++ + G + C V+ P +
Sbjct: 465 GGVYRCTANNSAG-VVLYQARINVRGPASIRPMKN-ITAIAGRDTYIHCRVIGYPYYSIK 522
Query: 294 WYQNSFPLSASERVTMSARGSNHTLLIADVQPE-DFGNYSC 333
WY+NS L + R A +N TL ++DVQ E D G Y+C
Sbjct: 523 WYKNSNLLPFNHR--QVAFENNGTLKLSDVQKEVDEGEYTC 561
Score = 66.9 bits (156), Expect = 2e-10
Identities = 64/225 (28%), Positives = 85/225 (37%), Gaps = 22/225 (9%)
Query: 149 GDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
G+Y C + A + + V VPP P R G A +L C A G PVPT+
Sbjct: 651 GNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP--RDQDGIYGKAVILNCSAEGYPVPTIV 708
Query: 208 WH-------------RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
W LN L G L + + G Y C V N VG V
Sbjct: 709 WKFSKGAGVPQFQPIALNGRIQVLSNG-SLLIKHVVEEDSGYYLCKVSNDVGADVSKSMY 767
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS---FPLSASERVTMSA 311
L V P IT + +G + E+ CT + P V W + P A V+
Sbjct: 768 LTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKE 827
Query: 312 RGSN--HTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
G TL I ED G +SC A NS G R ++++ + P
Sbjct: 828 VGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPP 872
Score = 63.7 bits (148), Expect = 1e-09
Identities = 52/182 (28%), Positives = 76/182 (41%), Gaps = 8/182 (4%)
Query: 183 HVTARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRLGEGPQ-LQLSRLERHHGGVYA 238
H A G L C+A G+P P W + N + S R + L + + G Y
Sbjct: 219 HRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENIRPSDSGSYV 278
Query: 239 CTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS 298
C V N G V +L V P + T+ V + G + L C+V E+SWY+N
Sbjct: 279 CEVSNRYGTAKVIG-RLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNG 337
Query: 299 FPLSASERVTMSARGSNHTLLIAD-VQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF 357
L+ + V ++ G NH LI D + D G Y C A+ +V+V G +
Sbjct: 338 EILNPGKNVRIT--GINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKI 395
Query: 358 TS 359
S
Sbjct: 396 IS 397
Score = 52.8 bits (121), Expect = 3e-06
Identities = 55/224 (24%), Positives = 89/224 (39%), Gaps = 20/224 (8%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+G YVC++S+R +V + V ++A+ R V + G L C G +
Sbjct: 273 DSGSYVCEVSNRYGTAKV-IGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQEL 331
Query: 207 TWHR----LNDSSSRLGEG---PQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+W+R LN + G L + + + GG Y C V + + +QV+
Sbjct: 332 SWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRK---DKLSAQDYVQVVL 388
Query: 260 ---PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL--SASERVTMSARGS 314
P+I S L+C V P ++W + P+ S R++
Sbjct: 389 EDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSE 448
Query: 315 NHT---LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
+ L I+ Q D G Y C A+NS G ++ R GPA
Sbjct: 449 GNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVR-GPA 491
Score = 51.2 bits (117), Expect = 8e-06
Identities = 51/225 (22%), Positives = 88/225 (39%), Gaps = 15/225 (6%)
Query: 146 QDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G Y C ++ + V P S+R +++TA G + CR G P
Sbjct: 463 RDGGVYRCTANNSAGVVLYQARINVRGPASIRPM---KNITAIAGRDTYIHCRVIGYPYY 519
Query: 205 TVTWHR------LNDSSSRLGEGPQLQLSRLERH-HGGVYACTVDNGVGPPVVTEFQLQV 257
++ W++ N L+LS +++ G Y C V V P + T + V
Sbjct: 520 SIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVL--VQPQLSTSQSVHV 577
Query: 258 LYP-PEITVERSWVHTGEGFRAELVCTVLA-DPPAEVSWYQNSFPLSASERVTMSARGSN 315
P + G R + C V++ D P ++W ++ P+ S VT+
Sbjct: 578 TVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFT 637
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
+L I+++ GNY+C+A N ++ R P P
Sbjct: 638 SSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP 682
Score = 44.4 bits (100), Expect = 0.001
Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 22/185 (11%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS---NHTLLIADVQPEDFGNYSCVAD 336
L C + DP V W ++S VT+ R S N + +I V+ ED G YSC+A+
Sbjct: 1291 LPCKAVGDPSPAVKWMKDSN--GTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIAN 1348
Query: 337 NSLGRAR--RHVEVSGRPGPARFTSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAIN 394
N+ G +++V P R T + S TLS+ P D R +
Sbjct: 1349 NNWGSDEIILNLQVQVPPDQPRLTVSKTTSS--SITLSWL-----PGDNGGSSIRGYILQ 1401
Query: 395 ESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVSDIFQ 454
S +W + +P+ + S+ L L+ Y+ + A+N G +S+I +
Sbjct: 1402 YSEDNSEQWGSFPI-SPSER-------SYRLENLKCGTWYKFTLTAQNGVGPGRISEIIE 1453
Query: 455 FHTLG 459
TLG
Sbjct: 1454 AKTLG 1458
Score = 33.9 bits (74), Expect = 1.3
Identities = 42/164 (25%), Positives = 66/164 (40%), Gaps = 23/164 (14%)
Query: 163 QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLG--E 220
++ TVE L R + VT VL C+A G+P P V W + ++ + L +
Sbjct: 1260 EIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTID 1319
Query: 221 GPQLQLSR-------LERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE---ITVER--- 267
G + S ++ G Y+C +N G + LQV PP+ +TV +
Sbjct: 1320 GRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEII-LNLQVQVPPDQPRLTVSKTTS 1378
Query: 268 -----SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASER 306
SW+ G + + + S SFP+S SER
Sbjct: 1379 SSITLSWLPGDNG--GSSIRGYILQYSEDNSEQWGSFPISPSER 1420
Score = 33.1 bits (72), Expect = 2.3
Identities = 34/135 (25%), Positives = 57/135 (42%), Gaps = 18/135 (13%)
Query: 143 MIFQDAGDYVCQISDRVARDQVHT--VEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ +D+G Y+C++S+ V D + + V +P + + P T A +G + C A G
Sbjct: 742 VVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNT--TLATQGQKKEMSCTAHG 799
Query: 201 NPVPTVTWHR----LND-------SSSRLGEG--PQLQLSRLERHHGGVYACTVDNGVGP 247
V W + +N S+ +GE LQ+ R G ++C N G
Sbjct: 800 EKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGE 859
Query: 248 PVVTEFQLQVLYPPE 262
QL V PP+
Sbjct: 860 DRGI-IQLTVQEPPD 873
>AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell
adhesion molecule isoform CHD2-42 precursor variant
protein.
Length = 2023
Score = 67.3 bits (157), Expect = 1e-10
Identities = 64/221 (28%), Positives = 98/221 (44%), Gaps = 23/221 (10%)
Query: 130 RITSEQHGNTNF-RMIFQDAGDYVCQI-SDRV-ARDQVHTVEVLVPPSVRASPETRHVTA 186
RIT H N M+ D G Y C + D++ A+D V V P + ++ + V+
Sbjct: 372 RITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVSP 431
Query: 187 RRGGAAVLECRAAGNPVPTVTW------------HRLNDSSSRLGE-GPQLQLSRLERHH 233
L C G P+PT+TW HR++ + G L +S +
Sbjct: 432 AE--PVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRD 489
Query: 234 GGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS 293
GGVY CT +N G V+ + ++ V P I ++ + G + C V+ P +
Sbjct: 490 GGVYRCTANNSAG-VVLYQARINVRGPASIRPMKN-ITAIAGRDTYIHCRVIGYPYYSIK 547
Query: 294 WYQNSFPLSASERVTMSARGSNHTLLIADVQPE-DFGNYSC 333
WY+NS L + R A +N TL ++DVQ E D G Y+C
Sbjct: 548 WYKNSNLLPFNHR--QVAFENNGTLKLSDVQKEVDEGEYTC 586
Score = 66.9 bits (156), Expect = 2e-10
Identities = 64/225 (28%), Positives = 85/225 (37%), Gaps = 22/225 (9%)
Query: 149 GDYVCQISDRVAR-DQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
G+Y C + A + + V VPP P R G A +L C A G PVPT+
Sbjct: 676 GNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP--RDQDGIYGKAVILNCSAEGYPVPTIV 733
Query: 208 WH-------------RLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
W LN L G L + + G Y C V N VG V
Sbjct: 734 WKFSKGAGVPQFQPIALNGRIQVLSNG-SLLIKHVVEEDSGYYLCKVSNDVGADVSKSMY 792
Query: 255 LQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS---FPLSASERVTMSA 311
L V P IT + +G + E+ CT + P V W + P A V+
Sbjct: 793 LTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKE 852
Query: 312 RGSN--HTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
G TL I ED G +SC A NS G R ++++ + P
Sbjct: 853 VGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPP 897
Score = 63.7 bits (148), Expect = 1e-09
Identities = 52/182 (28%), Positives = 76/182 (41%), Gaps = 8/182 (4%)
Query: 183 HVTARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRLGEGPQ-LQLSRLERHHGGVYA 238
H A G L C+A G+P P W + N + S R + L + + G Y
Sbjct: 244 HRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENIRPSDSGSYV 303
Query: 239 CTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS 298
C V N G V +L V P + T+ V + G + L C+V E+SWY+N
Sbjct: 304 CEVSNRYGTAKVIG-RLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNG 362
Query: 299 FPLSASERVTMSARGSNHTLLIAD-VQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF 357
L+ + V ++ G NH LI D + D G Y C A+ +V+V G +
Sbjct: 363 EILNPGKNVRIT--GINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKI 420
Query: 358 TS 359
S
Sbjct: 421 IS 422
Score = 52.8 bits (121), Expect = 3e-06
Identities = 55/224 (24%), Positives = 89/224 (39%), Gaps = 20/224 (8%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+G YVC++S+R +V + V ++A+ R V + G L C G +
Sbjct: 298 DSGSYVCEVSNRYGTAKV-IGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQEL 356
Query: 207 TWHR----LNDSSSRLGEG---PQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+W+R LN + G L + + + GG Y C V + + +QV+
Sbjct: 357 SWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRK---DKLSAQDYVQVVL 413
Query: 260 ---PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL--SASERVTMSARGS 314
P+I S L+C V P ++W + P+ S R++
Sbjct: 414 EDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSE 473
Query: 315 NHT---LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPA 355
+ L I+ Q D G Y C A+NS G ++ R GPA
Sbjct: 474 GNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVR-GPA 516
Score = 51.2 bits (117), Expect = 8e-06
Identities = 51/225 (22%), Positives = 88/225 (39%), Gaps = 15/225 (6%)
Query: 146 QDAGDYVCQISDRVARDQVHT-VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G Y C ++ + V P S+R +++TA G + CR G P
Sbjct: 488 RDGGVYRCTANNSAGVVLYQARINVRGPASIRPM---KNITAIAGRDTYIHCRVIGYPYY 544
Query: 205 TVTWHR------LNDSSSRLGEGPQLQLSRLERH-HGGVYACTVDNGVGPPVVTEFQLQV 257
++ W++ N L+LS +++ G Y C V V P + T + V
Sbjct: 545 SIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVL--VQPQLSTSQSVHV 602
Query: 258 LYP-PEITVERSWVHTGEGFRAELVCTVLA-DPPAEVSWYQNSFPLSASERVTMSARGSN 315
P + G R + C V++ D P ++W ++ P+ S VT+
Sbjct: 603 TVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFT 662
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
+L I+++ GNY+C+A N ++ R P P
Sbjct: 663 SSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP 707
Score = 44.4 bits (100), Expect = 0.001
Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 22/185 (11%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS---NHTLLIADVQPEDFGNYSCVAD 336
L C + DP V W ++S VT+ R S N + +I V+ ED G YSC+A+
Sbjct: 1316 LPCKAVGDPSPAVKWMKDSN--GTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIAN 1373
Query: 337 NSLGRAR--RHVEVSGRPGPARFTSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAIN 394
N+ G +++V P R T + S TLS+ P D R +
Sbjct: 1374 NNWGSDEIILNLQVQVPPDQPRLTVSKTTSS--SITLSWL-----PGDNGGSSIRGYILQ 1426
Query: 395 ESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVSDIFQ 454
S +W + +P+ + S+ L L+ Y+ + A+N G +S+I +
Sbjct: 1427 YSEDNSEQWGSFPI-SPSER-------SYRLENLKCGTWYKFTLTAQNGVGPGRISEIIE 1478
Query: 455 FHTLG 459
TLG
Sbjct: 1479 AKTLG 1483
Score = 33.9 bits (74), Expect = 1.3
Identities = 42/164 (25%), Positives = 66/164 (40%), Gaps = 23/164 (14%)
Query: 163 QVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLG--E 220
++ TVE L R + VT VL C+A G+P P V W + ++ + L +
Sbjct: 1285 EIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTID 1344
Query: 221 GPQLQLSR-------LERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPE---ITVER--- 267
G + S ++ G Y+C +N G + LQV PP+ +TV +
Sbjct: 1345 GRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEII-LNLQVQVPPDQPRLTVSKTTS 1403
Query: 268 -----SWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASER 306
SW+ G + + + S SFP+S SER
Sbjct: 1404 SSITLSWLPGDNG--GSSIRGYILQYSEDNSEQWGSFPISPSER 1445
Score = 33.1 bits (72), Expect = 2.3
Identities = 34/135 (25%), Positives = 57/135 (42%), Gaps = 18/135 (13%)
Query: 143 MIFQDAGDYVCQISDRVARDQVHT--VEVLVPPSVRASPETRHVTARRGGAAVLECRAAG 200
++ +D+G Y+C++S+ V D + + V +P + + P T A +G + C A G
Sbjct: 767 VVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNT--TLATQGQKKEMSCTAHG 824
Query: 201 NPVPTVTWHR----LND-------SSSRLGEG--PQLQLSRLERHHGGVYACTVDNGVGP 247
V W + +N S+ +GE LQ+ R G ++C N G
Sbjct: 825 EKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGE 884
Query: 248 PVVTEFQLQVLYPPE 262
QL V PP+
Sbjct: 885 DRGI-IQLTVQEPPD 898
>DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein.
Length = 1378
Score = 66.9 bits (156), Expect = 2e-10
Identities = 63/241 (26%), Positives = 96/241 (39%), Gaps = 17/241 (7%)
Query: 147 DAGDYVC----QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAA-GN 201
D G YVC + + V+R+ V L+ R +P V A G A+LEC+ G+
Sbjct: 104 DEGSYVCVARNYLGEAVSRNASLEV-ALLRDDFRQNPTDVVVAA--GEPAILECQPPRGH 160
Query: 202 PVPTVTWH----RLNDSSSRLG-EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P PT+ W R++D R+ G +L +S + G+Y C N VG +L
Sbjct: 161 PEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELT 220
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
V P E E C V DP V W ++ L R + ++
Sbjct: 221 VFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-RYDIK---DDY 276
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTLSFAVD 376
TL I D G Y C+A+N +G+ ++ R P P T++F +
Sbjct: 277 TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCE 336
Query: 377 S 377
+
Sbjct: 337 T 337
Score = 63.3 bits (147), Expect = 2e-09
Identities = 58/215 (26%), Positives = 87/215 (40%), Gaps = 27/215 (12%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C +RV + + T+ V PP P + V +G C GNP P
Sbjct: 287 DEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVA--QGRTVTFPCETKGNPQPA 344
Query: 206 VTWHRLNDS-----------SSRLGEGP--QLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
V W + +SR P L ++ ++R G Y C G ++ +
Sbjct: 345 VFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAG-SILAK 403
Query: 253 FQLQVL-----YPPEITVERSWVHT-GEGFRAELVCTVLADPPAEVSWYQNSFPLSASE- 305
QL+V PP I ++ T A L C DP +SW + F +
Sbjct: 404 AQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDP 463
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
R T+ +G TL I +++ D G Y+CVA +S G
Sbjct: 464 RATIQEQG---TLQIKNLRISDTGTYTCVATSSSG 495
Score = 46.8 bits (106), Expect = 2e-04
Identities = 49/186 (26%), Positives = 71/186 (38%), Gaps = 22/186 (11%)
Query: 172 PPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHR--------LNDSSSRLGEGPQ 223
PP + P V +G L C+A G P PT+ W++ +D S P
Sbjct: 30 PPRIVEHPSD--VIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPS 87
Query: 224 LQLSRLERHHG-------GVYACTVDNGVGPPVVTEFQLQV-LYPPEITVERSWVHTGEG 275
L L HG G Y C N +G V L+V L + + V G
Sbjct: 88 GSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAG 147
Query: 276 FRAELVC-TVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCV 334
A L C P + W ++ + E +S RG L+I++ + D G Y+CV
Sbjct: 148 EPAILECQPPRGHPEPTIYWKKDKVRIDDKEE-RISIRGGK--LMISNTRKSDAGMYTCV 204
Query: 335 ADNSLG 340
N +G
Sbjct: 205 GTNMVG 210
Score = 31.5 bits (68), Expect = 7.1
Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 7/91 (7%)
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR-----G 313
+PP I S V +G L C P + WY++ + + S R G
Sbjct: 29 FPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSG 88
Query: 314 SNHTLLIADVQ--PEDFGNYSCVADNSLGRA 342
S L I + D G+Y CVA N LG A
Sbjct: 89 SLFFLRIVHGRRSKPDEGSYVCVARNYLGEA 119
>DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein.
Length = 1394
Score = 66.9 bits (156), Expect = 2e-10
Identities = 63/241 (26%), Positives = 96/241 (39%), Gaps = 17/241 (7%)
Query: 147 DAGDYVC----QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAA-GN 201
D G YVC + + V+R+ V L+ R +P V A G A+LEC+ G+
Sbjct: 120 DEGSYVCVARNYLGEAVSRNASLEV-ALLRDDFRQNPTDVVVAA--GEPAILECQPPRGH 176
Query: 202 PVPTVTWH----RLNDSSSRLG-EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P PT+ W R++D R+ G +L +S + G+Y C N VG +L
Sbjct: 177 PEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELT 236
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
V P E E C V DP V W ++ L R + ++
Sbjct: 237 VFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-RYDIK---DDY 292
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTLSFAVD 376
TL I D G Y C+A+N +G+ ++ R P P T++F +
Sbjct: 293 TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCE 352
Query: 377 S 377
+
Sbjct: 353 T 353
Score = 63.3 bits (147), Expect = 2e-09
Identities = 58/215 (26%), Positives = 87/215 (40%), Gaps = 27/215 (12%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C +RV + + T+ V PP P + V +G C GNP P
Sbjct: 303 DEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVA--QGRTVTFPCETKGNPQPA 360
Query: 206 VTWHRLNDS-----------SSRLGEGP--QLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
V W + +SR P L ++ ++R G Y C G ++ +
Sbjct: 361 VFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAG-SILAK 419
Query: 253 FQLQVL-----YPPEITVERSWVHT-GEGFRAELVCTVLADPPAEVSWYQNSFPLSASE- 305
QL+V PP I ++ T A L C DP +SW + F +
Sbjct: 420 AQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDP 479
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
R T+ +G TL I +++ D G Y+CVA +S G
Sbjct: 480 RATIQEQG---TLQIKNLRISDTGTYTCVATSSSG 511
Score = 46.8 bits (106), Expect = 2e-04
Identities = 49/186 (26%), Positives = 71/186 (38%), Gaps = 22/186 (11%)
Query: 172 PPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHR--------LNDSSSRLGEGPQ 223
PP + P V +G L C+A G P PT+ W++ +D S P
Sbjct: 46 PPRIVEHPSD--VIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPS 103
Query: 224 LQLSRLERHHG-------GVYACTVDNGVGPPVVTEFQLQV-LYPPEITVERSWVHTGEG 275
L L HG G Y C N +G V L+V L + + V G
Sbjct: 104 GSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAG 163
Query: 276 FRAELVC-TVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCV 334
A L C P + W ++ + E +S RG L+I++ + D G Y+CV
Sbjct: 164 EPAILECQPPRGHPEPTIYWKKDKVRIDDKEE-RISIRGGK--LMISNTRKSDAGMYTCV 220
Query: 335 ADNSLG 340
N +G
Sbjct: 221 GTNMVG 226
Score = 31.5 bits (68), Expect = 7.1
Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 7/91 (7%)
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR-----G 313
+PP I S V +G L C P + WY++ + + S R G
Sbjct: 45 FPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSG 104
Query: 314 SNHTLLIADVQ--PEDFGNYSCVADNSLGRA 342
S L I + D G+Y CVA N LG A
Sbjct: 105 SLFFLRIVHGRRSKPDEGSYVCVARNYLGEA 135
>BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein.
Length = 1028
Score = 66.9 bits (156), Expect = 2e-10
Identities = 68/260 (26%), Positives = 104/260 (40%), Gaps = 27/260 (10%)
Query: 124 VWETTRRITSEQHGNTNFRMIF-QDAGDYVCQISDRVARDQVH---------TVEVL--V 171
V E RR S++ GN + D G+Y C I+++ A+ V T V+
Sbjct: 166 VQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEY 225
Query: 172 PPSVRAS-PETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQ------L 224
P + PET + A + + LEC A GNPVP ++W RL D S G+ L
Sbjct: 226 EPKIEVRFPET--IQAAKDSSVKLECFALGNPVPDISWRRL-DGSPLPGKVKYSKSQAIL 282
Query: 225 QLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTV 284
++ ++ G Y C N G + + QL PPE + H C
Sbjct: 283 EIPNFQQEDEGFYECIASNLRGRN-LAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKA 341
Query: 285 LADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
P +W +N L+ ER+ + N TL+I + D G Y C A+N
Sbjct: 342 SGKPNPWYTWLKNGERLNPEERIQI----ENGTLIITMLNVSDSGVYQCAAENKYQIIYA 397
Query: 345 HVEVSGRPGPARFTSPPLAR 364
+ E+ F+ P+ +
Sbjct: 398 NAELRVLASAPDFSKSPVKK 417
Score = 60.9 bits (141), Expect = 1e-08
Identities = 56/208 (26%), Positives = 90/208 (43%), Gaps = 18/208 (8%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVL-VPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G Y C S+ R+ + PP + H++ + EC+A+G P P
Sbjct: 290 EDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDN--LLWECKASGKPNP 347
Query: 205 TVTW----HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
TW RLN E L ++ L GVY C +N + +L+VL
Sbjct: 348 WYTWLKNGERLNPEERIQIENGTLIITMLNVSDSGVYQCAAENKY-QIIYANAELRVLAS 406
Query: 261 -PEITV----ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
P+ + ++S+V G + C A P A +SW + + L S+R+ + GS
Sbjct: 407 APDFSKSPVKKKSFVQVGGDI--VIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGS- 463
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRAR 343
L I ++ D G+Y+C+A N G A+
Sbjct: 464 --LKIYNITRSDAGSYTCIATNQFGTAK 489
Score = 48.8 bits (111), Expect = 4e-05
Identities = 52/174 (29%), Positives = 69/174 (39%), Gaps = 19/174 (10%)
Query: 193 VLECRAAGNPVPTVTWHR----LNDSSS---RLGEGPQLQLSRLERHHGGVYACTVDNGV 245
+L C A G P P W + ++ + S RL G S G+Y C N +
Sbjct: 47 ILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNLL 106
Query: 246 GPPVVTEFQLQVLYPPEI-TVERSWVHTGEGFRAELVCTVLADPP----AEVSWYQNSFP 300
G + + +LQ Y + T RS V EG L+C PP +W N P
Sbjct: 107 GTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLC---GPPPHFGDLSYAWTFNDNP 163
Query: 301 LSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
L E L IA V+P D GNY+C N A+R V+ G P P
Sbjct: 164 LYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNK--EAQRSVQ--GPPTP 213
>AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein.
Length = 1380
Score = 66.9 bits (156), Expect = 2e-10
Identities = 63/241 (26%), Positives = 96/241 (39%), Gaps = 17/241 (7%)
Query: 147 DAGDYVC----QISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAA-GN 201
D G YVC + + V+R+ V L+ R +P V A G A+LEC+ G+
Sbjct: 106 DEGSYVCVARNYLGEAVSRNASLEV-ALLRDDFRQNPTDVVVAA--GEPAILECQPPRGH 162
Query: 202 PVPTVTWH----RLNDSSSRLG-EGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQ 256
P PT+ W R++D R+ G +L +S + G+Y C N VG +L
Sbjct: 163 PEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELT 222
Query: 257 VLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH 316
V P E E C V DP V W ++ L R + ++
Sbjct: 223 VFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-RYDIK---DDY 278
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTLSFAVD 376
TL I D G Y C+A+N +G+ ++ R P P T++F +
Sbjct: 279 TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCE 338
Query: 377 S 377
+
Sbjct: 339 T 339
Score = 63.3 bits (147), Expect = 2e-09
Identities = 58/215 (26%), Positives = 87/215 (40%), Gaps = 27/215 (12%)
Query: 147 DAGDYVCQISDRVARDQVH-TVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D G Y+C +RV + + T+ V PP P + V +G C GNP P
Sbjct: 289 DEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVA--QGRTVTFPCETKGNPQPA 346
Query: 206 VTWHRLNDS-----------SSRLGEGP--QLQLSRLERHHGGVYACTVDNGVGPPVVTE 252
V W + +SR P L ++ ++R G Y C G ++ +
Sbjct: 347 VFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAG-SILAK 405
Query: 253 FQLQVL-----YPPEITVERSWVHT-GEGFRAELVCTVLADPPAEVSWYQNSFPLSASE- 305
QL+V PP I ++ T A L C DP +SW + F +
Sbjct: 406 AQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDP 465
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
R T+ +G TL I +++ D G Y+CVA +S G
Sbjct: 466 RATIQEQG---TLQIKNLRISDTGTYTCVATSSSG 497
Score = 46.8 bits (106), Expect = 2e-04
Identities = 49/186 (26%), Positives = 71/186 (38%), Gaps = 22/186 (11%)
Query: 172 PPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHR--------LNDSSSRLGEGPQ 223
PP + P V +G L C+A G P PT+ W++ +D S P
Sbjct: 32 PPRIVEHPSD--VIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPS 89
Query: 224 LQLSRLERHHG-------GVYACTVDNGVGPPVVTEFQLQV-LYPPEITVERSWVHTGEG 275
L L HG G Y C N +G V L+V L + + V G
Sbjct: 90 GSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAG 149
Query: 276 FRAELVC-TVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCV 334
A L C P + W ++ + E +S RG L+I++ + D G Y+CV
Sbjct: 150 EPAILECQPPRGHPEPTIYWKKDKVRIDDKEE-RISIRGGK--LMISNTRKSDAGMYTCV 206
Query: 335 ADNSLG 340
N +G
Sbjct: 207 GTNMVG 212
Score = 31.5 bits (68), Expect = 7.1
Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 7/91 (7%)
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR-----G 313
+PP I S V +G L C P + WY++ + + S R G
Sbjct: 31 FPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSG 90
Query: 314 SNHTLLIADVQ--PEDFGNYSCVADNSLGRA 342
S L I + D G+Y CVA N LG A
Sbjct: 91 SLFFLRIVHGRRSKPDEGSYVCVARNYLGEA 121
>AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecule
NB-3 protein.
Length = 1028
Score = 66.9 bits (156), Expect = 2e-10
Identities = 68/260 (26%), Positives = 104/260 (40%), Gaps = 27/260 (10%)
Query: 124 VWETTRRITSEQHGNTNFRMIF-QDAGDYVCQISDRVARDQVH---------TVEVL--V 171
V E RR S++ GN + D G+Y C I+++ A+ V T V+
Sbjct: 166 VQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEY 225
Query: 172 PPSVRAS-PETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQ------L 224
P + PET + A + + LEC A GNPVP ++W RL D S G+ L
Sbjct: 226 EPKIEVRFPET--IQAAKDSSVKLECFALGNPVPDISWRRL-DGSPLPGKVKYSKSQAIL 282
Query: 225 QLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTV 284
++ ++ G Y C N G + + QL PPE + H C
Sbjct: 283 EIPNFQQEDEGFYECIASNLRGRN-LAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKA 341
Query: 285 LADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARR 344
P +W +N L+ ER+ + N TL+I + D G Y C A+N
Sbjct: 342 SGKPNPWYTWLKNGERLNPEERIQI----ENGTLIITMLNVSDSGVYQCAAENKYQIIYA 397
Query: 345 HVEVSGRPGPARFTSPPLAR 364
+ E+ F+ P+ +
Sbjct: 398 NAELRVLASAPDFSKSPVKK 417
Score = 60.9 bits (141), Expect = 1e-08
Identities = 56/208 (26%), Positives = 90/208 (43%), Gaps = 18/208 (8%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVL-VPPSVRASPETRHVTARRGGAAVLECRAAGNPVP 204
+D G Y C S+ R+ + PP + H++ + EC+A+G P P
Sbjct: 290 EDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDN--LLWECKASGKPNP 347
Query: 205 TVTW----HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
TW RLN E L ++ L GVY C +N + +L+VL
Sbjct: 348 WYTWLKNGERLNPEERIQIENGTLIITMLNVSDSGVYQCAAENKY-QIIYANAELRVLAS 406
Query: 261 -PEITV----ERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN 315
P+ + ++S+V G + C A P A +SW + + L S+R+ + GS
Sbjct: 407 APDFSKSPVKKKSFVQVGGDI--VIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGS- 463
Query: 316 HTLLIADVQPEDFGNYSCVADNSLGRAR 343
L I ++ D G+Y+C+A N G A+
Sbjct: 464 --LKIYNITRSDAGSYTCIATNQFGTAK 489
Score = 48.8 bits (111), Expect = 4e-05
Identities = 52/174 (29%), Positives = 69/174 (39%), Gaps = 19/174 (10%)
Query: 193 VLECRAAGNPVPTVTWHR----LNDSSS---RLGEGPQLQLSRLERHHGGVYACTVDNGV 245
+L C A G P P W + ++ + S RL G S G+Y C N +
Sbjct: 47 ILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPHTDQDIGMYQCLATNLL 106
Query: 246 GPPVVTEFQLQVLYPPEI-TVERSWVHTGEGFRAELVCTVLADPP----AEVSWYQNSFP 300
G + + +LQ Y + T RS V EG L+C PP +W N P
Sbjct: 107 GTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLC---GPPPHFGDLSYAWTFNDNP 163
Query: 301 LSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
L E L IA V+P D GNY+C N A+R V+ G P P
Sbjct: 164 LYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNK--EAQRSVQ--GPPTP 213
>AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain
polypeptide kinase isoform 1 protein.
Length = 1914
Score = 66.5 bits (155), Expect = 2e-10
Identities = 67/255 (26%), Positives = 99/255 (38%), Gaps = 29/255 (11%)
Query: 146 QDAGDYVCQISD---RVARDQVHTVEVLVPPSVRASPET--RHVTARRGGAAVLECRAAG 200
+D+G Y C S+ +V+ VE L V S + + G VL+C G
Sbjct: 480 RDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG 539
Query: 201 NPVPTVTW----HRLNDSSSRLGEG-PQLQLSRLERHHGGVYACTVDNGVGPPVVTEF-- 253
PVP +TW + + S G +L + G Y C +N +G + +
Sbjct: 540 TPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
Query: 254 --------QLQVLYP--------PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQN 297
+ + L P P S + +G + + V +PP EV W N
Sbjct: 600 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
Query: 298 SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF 357
+ SE RG+ H+L I +V PED G Y+C A NS G R ++ + P
Sbjct: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-PHDG 718
Query: 358 TSPPLARAPHSYTLS 372
T P P S T S
Sbjct: 719 TQPWFISKPRSVTAS 733
Score = 61.3 bits (142), Expect = 8e-09
Identities = 32/86 (37%), Positives = 44/86 (51%)
Query: 270 VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFG 329
VH EG + L C V +DPPA + W N L ++ + +S GS ++ I PED G
Sbjct: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
Query: 330 NYSCVADNSLGRARRHVEVSGRPGPA 355
Y CVA N G+A +V+ PA
Sbjct: 1167 LYKCVAKNDAGQAECSCQVTVDDAPA 1192
Score = 55.6 bits (128), Expect = 4e-07
Identities = 50/184 (27%), Positives = 73/184 (39%), Gaps = 21/184 (11%)
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWH------RLNDSSSRLGEGP---Q 223
P + P+++ V + C +G P P V W R + S + E
Sbjct: 414 PKFESKPQSQEV--KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYENAGSHY 471
Query: 224 LQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV--LYPPEITVERSWVHTG----EGFR 277
L L + G Y+CT N G V + LQV L E+ S V EG
Sbjct: 472 LCLLKARTRDSGTYSCTASNAQGQ-VSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQD 530
Query: 278 AELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADN 337
L C+V P ++W N P+ + + H I D PED G Y+C+A+N
Sbjct: 531 FVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH---IQDALPEDHGTYTCLAEN 587
Query: 338 SLGR 341
+LG+
Sbjct: 588 ALGQ 591
Score = 54.8 bits (126), Expect = 7e-07
Identities = 27/90 (30%), Positives = 42/90 (46%)
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
PP+ + V EG C + P +V+W + + PL S RV++S + L
Sbjct: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
Query: 320 IADVQPEDFGNYSCVADNSLGRARRHVEVS 349
I V +D G Y+C+ N G+A E+S
Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELS 249
Score = 41.1 bits (92), Expect = 0.009
Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA--RGSNHTLLIADVQPEDFGNY 331
EG A+ V P +V+W++N P+++ R + RG+ +L+I V ED G Y
Sbjct: 46 EGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVIHAVHEEDRGKY 104
Query: 332 SCVADNSLGRARRHVEVS 349
+C A N G + VE++
Sbjct: 105 TCEATNGSGARQVTVELT 122
Score = 41.1 bits (92), Expect = 0.009
Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA-RGSNHTLLIADVQPEDFGNYS 332
EG A C + P EV W+++ + S + N +L+I+DV +D Y+
Sbjct: 1822 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1881
Query: 333 CVADNSLGRA 342
C A NSLG A
Sbjct: 1882 CKAVNSLGEA 1891
Score = 40.3 bits (90), Expect = 0.015
Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 13/114 (11%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASP----ETRHVTARRGGAAVLECRAAGN 201
+D G Y C+ + + V + P P + R VTA G + ++ C AG+
Sbjct: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGD 747
Query: 202 PVPTVTWHRLNDSSSR-LGEGPQLQ--------LSRLERHHGGVYACTVDNGVG 246
P PTV W R + + G LQ L +++ H G Y + N VG
Sbjct: 748 PFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
Score = 37.1 bits (82), Expect = 0.14
Identities = 48/195 (24%), Positives = 70/195 (35%), Gaps = 19/195 (9%)
Query: 189 GGAAVLECRAAGNPVPTVTW-HRLNDSSS-------RLGEGPQLQLSRLERHHGGVYACT 240
G + + +GNP P V W H N+ + G L + + G Y C
Sbjct: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
Query: 241 VDNGVGPPVVTEFQLQVLYPPE------ITVERSWVHTGEGFRAELVCTVLADPPAEVSW 294
N G V T+ L V P + I+ RS V G + C + DP V W
Sbjct: 697 AWNSAGE-VRTQAVLTVQEPHDGTQPWFISKPRS-VTASLGQSVLISCAIAGDPFPTVHW 754
Query: 295 YQNSFPLSASE-RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
++ L + TL++ VQP G Y + N +G V + +
Sbjct: 755 LRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNS 814
Query: 354 PARFTSPPLARAPHS 368
AR + P R P S
Sbjct: 815 SAR--ALPRGREPAS 827
Score = 35.1 bits (77), Expect = 0.58
Identities = 30/113 (26%), Positives = 44/113 (38%), Gaps = 11/113 (9%)
Query: 148 AGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
A ++ + S V +V ++ + P+ P R++ + G A E R G P P VT
Sbjct: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPP--RNLCIKEGATAKFEGRVRGYPEPQVT 65
Query: 208 WHRLNDSSSRLG--------EGP-QLQLSRLERHHGGVYACTVDNGVGPPVVT 251
WHR + G G L + + G Y C NG G VT
Sbjct: 66 WHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVT 118
Score = 34.7 bits (76), Expect = 0.76
Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 9/106 (8%)
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRLG----EGPQ-LQLSRLERHHGG 235
V + G C+ G P P VTW + N S+R+ G Q L++ + + G
Sbjct: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
Query: 236 VYACTVDNGVGPPVVT-EFQLQVLYPPEITVERSWVHTGEGFRAEL 280
VY C V NG G ++ E +Q L + R T R E+
Sbjct: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEV 275
>AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain
kinase protein.
Length = 1914
Score = 66.5 bits (155), Expect = 2e-10
Identities = 67/255 (26%), Positives = 99/255 (38%), Gaps = 29/255 (11%)
Query: 146 QDAGDYVCQISD---RVARDQVHTVEVLVPPSVRASPET--RHVTARRGGAAVLECRAAG 200
+D+G Y C S+ +V+ VE L V S + + G VL+C G
Sbjct: 480 RDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG 539
Query: 201 NPVPTVTW----HRLNDSSSRLGEG-PQLQLSRLERHHGGVYACTVDNGVGPPVVTEF-- 253
PVP +TW + + S G +L + G Y C +N +G + +
Sbjct: 540 TPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
Query: 254 --------QLQVLYP--------PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQN 297
+ + L P P S + +G + + V +PP EV W N
Sbjct: 600 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
Query: 298 SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF 357
+ SE RG+ H+L I +V PED G Y+C A NS G R ++ + P
Sbjct: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-PHDG 718
Query: 358 TSPPLARAPHSYTLS 372
T P P S T S
Sbjct: 719 TQPWFISKPRSVTAS 733
Score = 61.3 bits (142), Expect = 8e-09
Identities = 32/86 (37%), Positives = 44/86 (51%)
Query: 270 VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFG 329
VH EG + L C V +DPPA + W N L ++ + +S GS ++ I PED G
Sbjct: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
Query: 330 NYSCVADNSLGRARRHVEVSGRPGPA 355
Y CVA N G+A +V+ PA
Sbjct: 1167 LYKCVAKNDAGQAECSCQVTVDDAPA 1192
Score = 55.2 bits (127), Expect = 5e-07
Identities = 51/185 (27%), Positives = 73/185 (39%), Gaps = 23/185 (12%)
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGP---------- 222
P + P+++ V + C +G P P V W L + R EG
Sbjct: 414 PKFESKPQSQEV--KENQTVKFRCEVSGIPKPEVAWF-LEGTPVRRQEGSIEVYEDAGSH 470
Query: 223 QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV--LYPPEITVERSWVHTG----EGF 276
L L + G Y+CT N G V + LQV L E+ S V EG
Sbjct: 471 YLCLLKARTRDSGTYSCTASNAQGQ-VSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQ 529
Query: 277 RAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVAD 336
L C+V P ++W N P+ + + H I D PED G Y+C+A+
Sbjct: 530 DFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH---IQDALPEDHGTYTCLAE 586
Query: 337 NSLGR 341
N+LG+
Sbjct: 587 NALGQ 591
Score = 54.8 bits (126), Expect = 7e-07
Identities = 27/90 (30%), Positives = 42/90 (46%)
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
PP+ + V EG C + P +V+W + + PL S RV++S + L
Sbjct: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
Query: 320 IADVQPEDFGNYSCVADNSLGRARRHVEVS 349
I V +D G Y+C+ N G+A E+S
Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELS 249
Score = 41.1 bits (92), Expect = 0.009
Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA--RGSNHTLLIADVQPEDFGNY 331
EG A+ V P +V+W++N P+++ R + RG+ +L+I V ED G Y
Sbjct: 46 EGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVIHAVHEEDRGKY 104
Query: 332 SCVADNSLGRARRHVEVS 349
+C A N G + VE++
Sbjct: 105 TCEATNGSGARQVTVELT 122
Score = 41.1 bits (92), Expect = 0.009
Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA-RGSNHTLLIADVQPEDFGNYS 332
EG A C + P EV W+++ + S + N +L+I+DV +D Y+
Sbjct: 1822 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1881
Query: 333 CVADNSLGRA 342
C A NSLG A
Sbjct: 1882 CKAVNSLGEA 1891
Score = 40.3 bits (90), Expect = 0.015
Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 13/114 (11%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASP----ETRHVTARRGGAAVLECRAAGN 201
+D G Y C+ + + V + P P + R VTA G + ++ C AG+
Sbjct: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGD 747
Query: 202 PVPTVTWHRLNDSSSR-LGEGPQLQ--------LSRLERHHGGVYACTVDNGVG 246
P PTV W R + + G LQ L +++ H G Y + N VG
Sbjct: 748 PFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
Score = 37.1 bits (82), Expect = 0.14
Identities = 48/195 (24%), Positives = 70/195 (35%), Gaps = 19/195 (9%)
Query: 189 GGAAVLECRAAGNPVPTVTW-HRLNDSSS-------RLGEGPQLQLSRLERHHGGVYACT 240
G + + +GNP P V W H N+ + G L + + G Y C
Sbjct: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
Query: 241 VDNGVGPPVVTEFQLQVLYPPE------ITVERSWVHTGEGFRAELVCTVLADPPAEVSW 294
N G V T+ L V P + I+ RS V G + C + DP V W
Sbjct: 697 AWNSAGE-VRTQAVLTVQEPHDGTQPWFISKPRS-VTASLGQSVLISCAIAGDPFPTVHW 754
Query: 295 YQNSFPLSASE-RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
++ L + TL++ VQP G Y + N +G V + +
Sbjct: 755 LRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNS 814
Query: 354 PARFTSPPLARAPHS 368
AR + P R P S
Sbjct: 815 SAR--ALPRGREPAS 827
Score = 35.1 bits (77), Expect = 0.58
Identities = 30/113 (26%), Positives = 44/113 (38%), Gaps = 11/113 (9%)
Query: 148 AGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
A ++ + S V +V ++ + P+ P R++ + G A E R G P P VT
Sbjct: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPP--RNLCIKEGATAKFEGRVRGYPEPQVT 65
Query: 208 WHRLNDSSSRLG--------EGP-QLQLSRLERHHGGVYACTVDNGVGPPVVT 251
WHR + G G L + + G Y C NG G VT
Sbjct: 66 WHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVT 118
Score = 34.7 bits (76), Expect = 0.76
Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 9/106 (8%)
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRLG----EGPQ-LQLSRLERHHGG 235
V + G C+ G P P VTW + N S+R+ G Q L++ + + G
Sbjct: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
Query: 236 VYACTVDNGVGPPVVT-EFQLQVLYPPEITVERSWVHTGEGFRAEL 280
VY C V NG G ++ E +Q L + R T R E+
Sbjct: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEV 275
>AY328482-1|AAP97010.1| 571|Homo sapiens MAM domain containing 1
protein.
Length = 571
Score = 66.5 bits (155), Expect = 2e-10
Identities = 80/334 (23%), Positives = 132/334 (39%), Gaps = 32/334 (9%)
Query: 137 GNTNFRMI---FQDAGDYVCQISDRVARDQVHTVEV-----LVPPSVRASPETRHVTARR 188
G TN +I F D G Y C S + +++V VPP++ E + R
Sbjct: 13 GTTNLDIIDLKFTDFGTYTCVASLKGGGISDISIDVNISSSTVPPNLTVPQEKSPLVTRE 72
Query: 189 GGAAVLECRAAGNPVPTVTWHR------LNDSSSRL-GEGPQLQLSRLERHHGGVYACTV 241
G L+C+ G P P + W R + D S ++ L++ + R G+Y C
Sbjct: 73 GDTIELQCQVTGKPKPIILWSRADKEVAMPDGSMQMESYDGTLRIVNVSREMSGMYRCQT 132
Query: 242 D--NGVG-PPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNS 298
NG P QL V YPP + + G+ + C VL P V Y+
Sbjct: 133 SQYNGFNVKPREALVQLIVQYPPAVEPAFLEIRQGQDRSVTMSCRVLRAYPIRVLTYE-- 190
Query: 299 FPLSASERVTMSARGSNHT-LLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF 357
+ L T +T + + E++G Y+C N G R V+G+ F
Sbjct: 191 WRLGNKLLRTGQFDSQEYTEYAVKSLSNENYGVYNCSIINEAGAGRCSFLVTGKAYAPEF 250
Query: 358 ---TSPPLARAPH---SYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAAP 411
T P+ + H SY+L + + +D R++ +L I ++ QQ ++ +
Sbjct: 251 YYDTYNPVWQNRHRVYSYSLQWTQMNPDAVD--RIVAYRLGIRQAGQQRWWEQEIKINGN 308
Query: 412 AAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYG 445
KG L +++ L L YE + ++G
Sbjct: 309 IQKGEL---ITYNLTELIKPEAYEVRLTPLTKFG 339
>U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase
protein.
Length = 1914
Score = 66.1 bits (154), Expect = 3e-10
Identities = 67/255 (26%), Positives = 99/255 (38%), Gaps = 29/255 (11%)
Query: 146 QDAGDYVCQISD---RVARDQVHTVEVLVPPSVRASPET--RHVTARRGGAAVLECRAAG 200
+D+G Y C S+ +V+ VE L V S + + G VL+C G
Sbjct: 480 RDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG 539
Query: 201 NPVPTVTW----HRLNDSSSRLGEG-PQLQLSRLERHHGGVYACTVDNGVGPPVVTEF-- 253
PVP +TW + + S G +L + G Y C +N +G + +
Sbjct: 540 TPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
Query: 254 --------QLQVLYP--------PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQN 297
+ + L P P S + +G + + V +PP EV W N
Sbjct: 600 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
Query: 298 SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF 357
+ SE RG+ H+L I +V PED G Y+C A NS G R ++ + P
Sbjct: 660 GNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-PHDG 718
Query: 358 TSPPLARAPHSYTLS 372
T P P S T S
Sbjct: 719 TQPWFISKPRSVTAS 733
Score = 61.3 bits (142), Expect = 8e-09
Identities = 32/86 (37%), Positives = 44/86 (51%)
Query: 270 VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFG 329
VH EG + L C V +DPPA + W N L ++ + +S GS ++ I PED G
Sbjct: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
Query: 330 NYSCVADNSLGRARRHVEVSGRPGPA 355
Y CVA N G+A +V+ PA
Sbjct: 1167 LYKCVAKNDAGQAECSCQVTVDDAPA 1192
Score = 55.2 bits (127), Expect = 5e-07
Identities = 51/185 (27%), Positives = 73/185 (39%), Gaps = 23/185 (12%)
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGP---------- 222
P + P+++ V + C +G P P V W L + R EG
Sbjct: 414 PKFESKPQSQEV--KENQTVKFRCEVSGIPKPEVAWF-LEGTPVRRQEGSIEVYEDAGSH 470
Query: 223 QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV--LYPPEITVERSWVHTG----EGF 276
L L + G Y+CT N G V + LQV L E+ S V EG
Sbjct: 471 YLCLLKARTRDSGTYSCTASNAQGQ-VSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQ 529
Query: 277 RAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVAD 336
L C+V P ++W N P+ + + H I D PED G Y+C+A+
Sbjct: 530 DFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH---IQDALPEDHGTYTCLAE 586
Query: 337 NSLGR 341
N+LG+
Sbjct: 587 NALGQ 591
Score = 54.8 bits (126), Expect = 7e-07
Identities = 27/90 (30%), Positives = 42/90 (46%)
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
PP+ + V EG C + P +V+W + + PL S RV++S + L
Sbjct: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
Query: 320 IADVQPEDFGNYSCVADNSLGRARRHVEVS 349
I V +D G Y+C+ N G+A E+S
Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELS 249
Score = 41.1 bits (92), Expect = 0.009
Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA--RGSNHTLLIADVQPEDFGNY 331
EG A+ V P +V+W++N P+++ R + RG+ +L+I V ED G Y
Sbjct: 46 EGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVIHAVHEEDRGKY 104
Query: 332 SCVADNSLGRARRHVEVS 349
+C A N G + VE++
Sbjct: 105 TCEATNGSGARQVTVELT 122
Score = 41.1 bits (92), Expect = 0.009
Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA-RGSNHTLLIADVQPEDFGNYS 332
EG A C + P EV W+++ + S + N +L+I+DV +D Y+
Sbjct: 1822 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1881
Query: 333 CVADNSLGRA 342
C A NSLG A
Sbjct: 1882 CKAVNSLGEA 1891
Score = 40.3 bits (90), Expect = 0.015
Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 13/114 (11%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASP----ETRHVTARRGGAAVLECRAAGN 201
+D G Y C+ + + V + P P + R VTA G + ++ C AG+
Sbjct: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGD 747
Query: 202 PVPTVTWHRLNDSSSR-LGEGPQLQ--------LSRLERHHGGVYACTVDNGVG 246
P PTV W R + + G LQ L +++ H G Y + N VG
Sbjct: 748 PFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
Score = 37.5 bits (83), Expect = 0.11
Identities = 48/195 (24%), Positives = 70/195 (35%), Gaps = 19/195 (9%)
Query: 189 GGAAVLECRAAGNPVPTVTW-HRLNDSSS-------RLGEGPQLQLSRLERHHGGVYACT 240
G + + +GNP P V W H N+ + G L + + G Y C
Sbjct: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCE 696
Query: 241 VDNGVGPPVVTEFQLQVLYPPE------ITVERSWVHTGEGFRAELVCTVLADPPAEVSW 294
N G V T+ L V P + I+ RS V G + C + DP V W
Sbjct: 697 AWNSAGE-VRTQAVLTVQEPHDGTQPWFISKPRS-VTASLGQSVLISCAIAGDPFPTVHW 754
Query: 295 YQNSFPLSASE-RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
++ L + TL++ VQP G Y + N +G V + +
Sbjct: 755 LRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNS 814
Query: 354 PARFTSPPLARAPHS 368
AR + P R P S
Sbjct: 815 SAR--ALPRGREPAS 827
Score = 35.1 bits (77), Expect = 0.58
Identities = 30/113 (26%), Positives = 44/113 (38%), Gaps = 11/113 (9%)
Query: 148 AGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
A ++ + S V +V ++ + P+ P R++ + G A E R G P P VT
Sbjct: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPP--RNLCIKEGATAKFEGRVRGYPEPQVT 65
Query: 208 WHRLNDSSSRLG--------EGP-QLQLSRLERHHGGVYACTVDNGVGPPVVT 251
WHR + G G L + + G Y C NG G VT
Sbjct: 66 WHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVT 118
Score = 34.7 bits (76), Expect = 0.76
Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 9/106 (8%)
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRLG----EGPQ-LQLSRLERHHGG 235
V + G C+ G P P VTW + N S+R+ G Q L++ + + G
Sbjct: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
Query: 236 VYACTVDNGVGPPVVT-EFQLQVLYPPEITVERSWVHTGEGFRAEL 280
VY C V NG G ++ E +Q L + R T R E+
Sbjct: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEV 275
>AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kinase
isoform 3A protein.
Length = 1862
Score = 66.1 bits (154), Expect = 3e-10
Identities = 67/255 (26%), Positives = 99/255 (38%), Gaps = 29/255 (11%)
Query: 146 QDAGDYVCQISD---RVARDQVHTVEVLVPPSVRASPET--RHVTARRGGAAVLECRAAG 200
+D+G Y C S+ +V+ VE L V S + + G VL+C G
Sbjct: 480 RDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG 539
Query: 201 NPVPTVTW----HRLNDSSSRLGEG-PQLQLSRLERHHGGVYACTVDNGVGPPVVTEF-- 253
PVP +TW + + S G +L + G Y C +N +G + +
Sbjct: 540 TPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
Query: 254 --------QLQVLYP--------PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQN 297
+ + L P P S + +G + + V +PP EV W N
Sbjct: 600 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
Query: 298 SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARF 357
+ SE RG+ H+L I +V PED G Y+C A NS G R ++ + P
Sbjct: 660 GNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-PHDG 718
Query: 358 TSPPLARAPHSYTLS 372
T P P S T S
Sbjct: 719 TQPWFISKPRSVTAS 733
Score = 57.2 bits (132), Expect = 1e-07
Identities = 31/86 (36%), Positives = 43/86 (50%)
Query: 270 VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFG 329
VH EG + L C V +DPPA + W N L ++ + +S GS ++ I ED G
Sbjct: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALLEDRG 1166
Query: 330 NYSCVADNSLGRARRHVEVSGRPGPA 355
Y CVA N G+A +V+ PA
Sbjct: 1167 LYKCVAKNDAGQAECSCQVTVDDAPA 1192
Score = 55.2 bits (127), Expect = 5e-07
Identities = 51/185 (27%), Positives = 73/185 (39%), Gaps = 23/185 (12%)
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGP---------- 222
P + P+++ V + C +G P P V W L + R EG
Sbjct: 414 PKFESKPQSQEV--KENQTVKFRCEVSGIPKPEVAWF-LEGTPVRRQEGSIEVYEDAGSH 470
Query: 223 QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV--LYPPEITVERSWVHTG----EGF 276
L L + G Y+CT N G V + LQV L E+ S V EG
Sbjct: 471 YLCLLKARTRDSGTYSCTASNAQGQ-VSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQ 529
Query: 277 RAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVAD 336
L C+V P ++W N P+ + + H I D PED G Y+C+A+
Sbjct: 530 DFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH---IQDALPEDHGTYTCLAE 586
Query: 337 NSLGR 341
N+LG+
Sbjct: 587 NALGQ 591
Score = 54.8 bits (126), Expect = 7e-07
Identities = 27/90 (30%), Positives = 42/90 (46%)
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
PP+ + V EG C + P +V+W + + PL S RV++S + L
Sbjct: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
Query: 320 IADVQPEDFGNYSCVADNSLGRARRHVEVS 349
I V +D G Y+C+ N G+A E+S
Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELS 249
Score = 41.1 bits (92), Expect = 0.009
Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA--RGSNHTLLIADVQPEDFGNY 331
EG A+ V P +V+W++N P+++ R + RG+ +L+I V ED G Y
Sbjct: 46 EGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVIHAVHEEDRGKY 104
Query: 332 SCVADNSLGRARRHVEVS 349
+C A N G + VE++
Sbjct: 105 TCEATNGSGARQVTVELT 122
Score = 41.1 bits (92), Expect = 0.009
Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA-RGSNHTLLIADVQPEDFGNYS 332
EG A C + P EV W+++ + S + N +L+I+DV +D Y+
Sbjct: 1770 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1829
Query: 333 CVADNSLGRA 342
C A NSLG A
Sbjct: 1830 CKAVNSLGEA 1839
Score = 40.3 bits (90), Expect = 0.015
Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 13/114 (11%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASP----ETRHVTARRGGAAVLECRAAGN 201
+D G Y C+ + + V + P P + R VTA G + ++ C AG+
Sbjct: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGD 747
Query: 202 PVPTVTWHRLNDSSSR-LGEGPQLQ--------LSRLERHHGGVYACTVDNGVG 246
P PTV W R + + G LQ L +++ H G Y + N VG
Sbjct: 748 PFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
Score = 37.5 bits (83), Expect = 0.11
Identities = 48/195 (24%), Positives = 70/195 (35%), Gaps = 19/195 (9%)
Query: 189 GGAAVLECRAAGNPVPTVTW-HRLNDSSS-------RLGEGPQLQLSRLERHHGGVYACT 240
G + + +GNP P V W H N+ + G L + + G Y C
Sbjct: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCE 696
Query: 241 VDNGVGPPVVTEFQLQVLYPPE------ITVERSWVHTGEGFRAELVCTVLADPPAEVSW 294
N G V T+ L V P + I+ RS V G + C + DP V W
Sbjct: 697 AWNSAGE-VRTQAVLTVQEPHDGTQPWFISKPRS-VTASLGQSVLISCAIAGDPFPTVHW 754
Query: 295 YQNSFPLSASE-RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
++ L + TL++ VQP G Y + N +G V + +
Sbjct: 755 LRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNS 814
Query: 354 PARFTSPPLARAPHS 368
AR + P R P S
Sbjct: 815 SAR--ALPRGREPAS 827
Score = 35.1 bits (77), Expect = 0.58
Identities = 30/113 (26%), Positives = 44/113 (38%), Gaps = 11/113 (9%)
Query: 148 AGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
A ++ + S V +V ++ + P+ P R++ + G A E R G P P VT
Sbjct: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPP--RNLCIKEGATAKFEGRVRGYPEPQVT 65
Query: 208 WHRLNDSSSRLG--------EGP-QLQLSRLERHHGGVYACTVDNGVGPPVVT 251
WHR + G G L + + G Y C NG G VT
Sbjct: 66 WHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVT 118
Score = 34.7 bits (76), Expect = 0.76
Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 9/106 (8%)
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRLG----EGPQ-LQLSRLERHHGG 235
V + G C+ G P P VTW + N S+R+ G Q L++ + + G
Sbjct: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
Query: 236 VYACTVDNGVGPPVVT-EFQLQVLYPPEITVERSWVHTGEGFRAEL 280
VY C V NG G ++ E +Q L + R T R E+
Sbjct: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEV 275
>AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1
protein.
Length = 2213
Score = 65.7 bits (153), Expect = 4e-10
Identities = 59/208 (28%), Positives = 92/208 (44%), Gaps = 17/208 (8%)
Query: 147 DAGDYVCQIS-DRVARDQVHTVE---VLVPPSVRASPETRHVTARRGGAAVLECRAAGNP 202
D G YVC+ + A + ++ PP A PE+R ++A + C+A G P
Sbjct: 356 DTGPYVCEAALPGSAFEPARATAFLFIIEPPYFTAEPESR-ISAEVEETVDIGCQAMGVP 414
Query: 203 VPTVTWHRLNDSSSRLGEGPQ--------LQLSRLERHHGGVYACTVDNGVGPPVVTEFQ 254
+PT+ W++ S SRL + P+ L++ +L G++ C N G + T
Sbjct: 415 LPTLQWYKDAISISRL-QNPRYKVLASGGLRIQKLRPEDSGIFQCFASN-EGGEIQTHTY 472
Query: 255 LQVLYPPEITVERSWVHT-GEGFRAELVCTVLADPPAEVSW-YQNSFPLSASERVTMSAR 312
L V + +R T +G A L C V P ++W +N S S R+
Sbjct: 473 LDVTNIAPVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFML 532
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLG 340
+ L IA V +D GNY+C A N+ G
Sbjct: 533 LESGGLQIAPVFIQDAGNYTCYAANTEG 560
Score = 57.6 bits (133), Expect = 9e-08
Identities = 58/212 (27%), Positives = 84/212 (39%), Gaps = 13/212 (6%)
Query: 159 VARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVP--TVTWHR--LNDS 214
+ARD V T E + P V P R V A LEC A+ PV +VTW R + +
Sbjct: 281 IARD-VGTPETMAPTIV-VPPGNRSVVAG-SSETTLECIASARPVEDLSVTWKRNGVRIT 337
Query: 215 SSRLGEGPQLQLSRLERHHGGVYACTV---DNGVGPPVVTEFQLQVLYPPEITVE-RSWV 270
S G L +S G Y C + P T F L ++ PP T E S +
Sbjct: 338 SGLHSFGRHLTISNPTSADTGPYVCEAALPGSAFEPARATAF-LFIIEPPYFTAEPESRI 396
Query: 271 HTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGN 330
++ C + P + WY+++ +S + S L I ++PED G
Sbjct: 397 SAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGG-LRIQKLRPEDSGI 455
Query: 331 YSCVADNSLGRARRHVEVSGRPGPARFTSPPL 362
+ C A N G + H + FT P+
Sbjct: 456 FQCFASNEGGEIQTHTYLDVTNIAPVFTQRPV 487
Score = 54.8 bits (126), Expect = 7e-07
Identities = 87/329 (26%), Positives = 133/329 (40%), Gaps = 48/329 (14%)
Query: 146 QDAGDYVCQISDRVARDQVHT-VEVL-VPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
+D+G + C S+ Q HT ++V + P P VT G A+L C +G P
Sbjct: 451 EDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRPVDTTVTD--GMTAILRCEVSGAPK 508
Query: 204 PTVTW----HRLNDSSSR-----LGEGPQLQLSRLERHHGGVYACTVDNGVG----PPVV 250
P +TW H L S R L E LQ++ + G Y C N G +
Sbjct: 509 PAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATL 568
Query: 251 TEF-QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVS--WYQNSFPL--SASE 305
T + + +++PPE V +G A L C DP + W +++ L S++
Sbjct: 569 TVWNRTSIVHPPEDHV------VIKGTTATLHCGATHDPRVSLRYVWKKDNVALTPSSTS 622
Query: 306 RVTMSARGSNHTLLIADVQPEDFGNYSC--VADNSLGRARRHVEVSGRP-GPARFTSPPL 362
R+ + GS LLI+ D G+YSC V++ +EV P P P
Sbjct: 623 RIVVEKDGS---LLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVIELPHSPQNLLVSPN 679
Query: 363 ARAPHSYTLSFAVDSYPPLD-ELRLLYRQLAINESFQQPGRWHDVVLAAPAAKGSLTHRV 421
+ H+ LS+ P D +LY + ++E+ P + H + P G
Sbjct: 680 SSHSHAVVLSWV----RPFDGNSPILYYIVELSEN-SSPWKVH-LSNVGPEMTGV----- 728
Query: 422 SHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ GL PA Y+ V A N G + S
Sbjct: 729 --TVSGLTPARTYQFRVCAVNEVGRGQYS 755
Score = 41.1 bits (92), Expect = 0.009
Identities = 41/181 (22%), Positives = 71/181 (39%), Gaps = 11/181 (6%)
Query: 163 QVHTVEVL----VPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRL 218
Q+H + L V P + P + G VL C A G+ W R + +
Sbjct: 90 QLHLLRALAQDDVAPYFKTEPGLPQIHLE-GNRLVLTCLAEGSWPLEFKWMRDDSELTTY 148
Query: 219 GEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEI--TVERSWVHTGEGF 276
+ + L++ G Y C V N +G + + ++QV Y T +R V G
Sbjct: 149 SSEYKYIIPSLQKLDAGFYRCVVRNRMGALLQRKSEVQVAYMGSFMDTDQRKTVSQGRAA 208
Query: 277 RAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVAD 336
L+ + + P +V+W++ + S R+ ++ + L+I D G Y A
Sbjct: 209 ILNLL-PITSYPRPQVTWFREGHKIIPSNRIAITL---ENQLVILATTTSDAGAYYVQAV 264
Query: 337 N 337
N
Sbjct: 265 N 265
Score = 32.7 bits (71), Expect = 3.1
Identities = 32/108 (29%), Positives = 45/108 (41%), Gaps = 11/108 (10%)
Query: 22 NDGPRFLSRGHSFRTVVGDTLLLPCQVQNLGSLVLLWRRAPAVLTAASLMVTRDERFRLV 81
N P F R G T +L C+V + W+R +L + S+ R RF L+
Sbjct: 477 NIAPVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSV---RIPRFMLL 533
Query: 82 DGYNLQITDVGPQIRYTVDVTIY-ENSETSVALAILGATGHTNVWETT 128
+ LQI V I+ + T Y N+E S L A+ VW T
Sbjct: 534 ESGGLQIAPV--FIQDAGNYTCYAANTEGS-----LNASATLTVWNRT 574
>EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein.
Length = 1248
Score = 65.3 bits (152), Expect = 5e-10
Identities = 60/230 (26%), Positives = 93/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 179 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 238
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D ++ LQL ++
Sbjct: 239 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRATYQNHNKTLQLLKVG 298
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 299 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 357
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 358 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 406
Score = 51.2 bits (117), Expect = 8e-06
Identities = 75/302 (24%), Positives = 118/302 (39%), Gaps = 33/302 (10%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 414 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 473
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 474 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVTDATQITQGPRSTIEKKGSRVTF 532
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 533 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 588
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 589 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 644
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + PG+W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 645 IEFEDKEMAPGKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 696
Query: 451 DI 452
+
Sbjct: 697 PV 698
Score = 46.4 bits (105), Expect = 2e-04
Identities = 61/238 (25%), Positives = 92/238 (38%), Gaps = 26/238 (10%)
Query: 138 NTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPET-RHVTARRGGAAVLEC 196
N+NF FQ G Y C S+++ H + ++ + + ET + V G + VL C
Sbjct: 96 NSNFAQRFQ--GIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPC 153
Query: 197 RAAGNPVPT-VTW------HRLNDSSSRLGEGPQLQLSR-LERHHGGVYACTVD-NGVGP 247
+ P + W H D +G+ L + L + Y C G
Sbjct: 154 NPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRT 213
Query: 248 PVVTE-FQLQVLYP-------PEI---TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ 296
+ E L+V P + T S + +G L C P + W +
Sbjct: 214 IIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLR 273
Query: 297 NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
S P+ A +R T + N TL + V ED G Y C+A+NSLG AR V+ P
Sbjct: 274 PSGPMPA-DRATY--QNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAP 328
>AY358128-1|AAQ88495.1| 717|Homo sapiens IGSF9 protein.
Length = 717
Score = 65.3 bits (152), Expect = 5e-10
Identities = 64/222 (28%), Positives = 94/222 (42%), Gaps = 18/222 (8%)
Query: 135 QHGNTNFRMIFQ-DAGDYVCQISDRVARDQVHTVEVLV--PPSVRASPETRHVTARRGGA 191
Q+G R + + +G Y CQ S H ++LV PP + P+ V A +
Sbjct: 187 QNGTLRIRRVERGSSGVYTCQASSTEG-SATHATQLLVLGPPVIVVPPKNSTVNASQD-- 243
Query: 192 AVLECRAAGNPVP-TVTWHRLNDSS---SRLGEGPQ------LQLSRLERHHGGVYACTV 241
A L C A P T +W + N + SRL + L+L + G Y C
Sbjct: 244 ASLACHAEAYPANLTYSWFQDNINVFHISRLQPRVRILVDGSLRLLATQPDDAGCYTCVP 303
Query: 242 DNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPP-AEVSWYQNSFP 300
NG+ P L VLYP ++T G + C V A+PP VSW ++
Sbjct: 304 SNGLLHPPSASAYLTVLYPAQVTAMPPETPLPIGMPGVIRCPVRANPPLLFVSWTKDGKA 363
Query: 301 LSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
L ++ ++G+ +L+IA + G YSC NSLG A
Sbjct: 364 LQL-DKFPGWSQGTEGSLIIALGNEDALGEYSCTPYNSLGTA 404
Score = 62.1 bits (144), Expect = 4e-09
Identities = 54/157 (34%), Positives = 69/157 (43%), Gaps = 16/157 (10%)
Query: 194 LECRAAGNPVPTVTWHRLNDSSSRLGEGP------QLQLSRLERHHGGVYACTVDNGVGP 247
L C A G+P+P VTW +L G+G L++ R+ER GVY C + G
Sbjct: 156 LRCVARGSPLPHVTW-KLRGKDLGQGQGQVQVQNGTLRIRRVERGSSGVYTCQASSTEG- 213
Query: 248 PVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPP-AEVSWYQ---NSFPLSA 303
QL VL PP I V A L C A P SW+Q N F +S
Sbjct: 214 SATHATQLLVLGPPVIVVPPKNSTVNASQDASLACHAEAYPANLTYSWFQDNINVFHISR 273
Query: 304 SE-RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
+ RV + GS L + QP+D G Y+CV N L
Sbjct: 274 LQPRVRILVDGS---LRLLATQPDDAGCYTCVPSNGL 307
>X90568-1|CAA62188.1|26926|Homo sapiens titin protein.
Length = 26926
Score = 64.9 bits (151), Expect = 6e-10
Identities = 62/223 (27%), Positives = 91/223 (40%), Gaps = 24/223 (10%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
DAG+Y ++ R R V T+ V P + E + VT + G A +G P P +
Sbjct: 3168 DAGEYTF-VAGR-NRSSV-TLYVNAPEPPQVLQELQPVTVQSGKPARFCAMISGRPQPKI 3224
Query: 207 TWHRLNDSSSR------LGEGPQLQLSRLER--HHGGVYACTVDNGVG------------ 246
+W++ S L +G + L +E VY C N G
Sbjct: 3225 SWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV 3284
Query: 247 PPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASER 306
P VV+ Q +YPP I T EG A C V + +VSWY + S
Sbjct: 3285 PEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIKPSRF 3343
Query: 307 VTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
M+ + L IA+ PED G Y+ VA+N++G+ +S
Sbjct: 3344 FRMTQFEDTYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLS 3386
Score = 62.9 bits (146), Expect = 3e-09
Identities = 53/177 (29%), Positives = 79/177 (44%), Gaps = 12/177 (6%)
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLND--SSSRL-------GEG-PQLQLSRLERHH 233
V G A E +G PVP V+W R S+S L +G +L + + + +
Sbjct: 15 VVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKAN 74
Query: 234 GGVYACTVDNGVGPPVVT-EFQLQVLYPPEITVERSWVHT-GEGFRAELVCTVLADPPAE 291
G Y+ NG G T E ++ P V+R T +G + L V P
Sbjct: 75 SGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPNPV 134
Query: 292 VSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
V +Y++ + +S +S G ++LLIA+ PED G YS A NS+GRA E+
Sbjct: 135 VKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAEL 191
Score = 56.0 bits (129), Expect = 3e-07
Identities = 28/80 (35%), Positives = 41/80 (51%)
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I E V T G A+L C ++ P ++ WY+ L S + MS+ G HTL +
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24095
Query: 321 ADVQPEDFGNYSCVADNSLG 340
+ ED G Y+C+A N +G
Sbjct: 24096 MTEEQEDEGVYTCIATNEVG 24115
Score = 52.4 bits (120), Expect = 4e-06
Identities = 55/225 (24%), Positives = 88/225 (39%), Gaps = 21/225 (9%)
Query: 173 PSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLND--------SSSRLGEGPQL 224
P +R E + VT + G AA L C+ G P+P + W+R S G L
Sbjct: 24036 PGIRK--EMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTL 24093
Query: 225 QLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEI-----TVERSWVHTGEGFRAE 279
+ E+ GVY C N VG V T +L + P+ E+ + G R
Sbjct: 24094 TVMTEEQEDEGVYTCIATNEVG-EVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLH 24152
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDF-GNYSCVADNS 338
++ + P ++W+ L SE +T+ L++ +VQ + G Y N
Sbjct: 24153 VM--YIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNV 24210
Query: 339 LGRARRHVEVSGRPGPARFTSPPLARAPHSYTLSFAVDSYPPLDE 383
G ++V + P + T P + A S + PP D+
Sbjct: 24211 FGTVDAILDVEIQDKPDKPTGPIVIEA--LLKNSAVISWKPPADD 24253
Score = 48.4 bits (110), Expect = 6e-05
Identities = 31/112 (27%), Positives = 53/112 (47%), Gaps = 5/112 (4%)
Query: 245 VGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
+G PV+ + L + ++ + GE + E+ V+ P +SW ++ PL +
Sbjct: 17802 LGVPVIAK-DLTIQPSLKLPFNTYSIQAGEDLKIEI--PVIGRPRPNISWVKDGEPLKQT 17858
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH--VEVSGRPGP 354
RV + ++ L I + +DFG Y+ A NS G A + V V +PGP
Sbjct: 17859 TRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGP 17910
Score = 48.0 bits (109), Expect = 8e-05
Identities = 30/96 (31%), Positives = 42/96 (43%), Gaps = 3/96 (3%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
EG A C +P V+W + LS S R ++ T I+ VQ D GNYS
Sbjct: 26077 EGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSV 26136
Query: 334 VADNSLGRARRHVEVS---GRPGPARFTSPPLARAP 366
V +NS G+ ++ R TSPP ++P
Sbjct: 26137 VVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSP 26172
Score = 46.4 bits (105), Expect = 2e-04
Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
P I+ RS + EG C + +P E+ W++N+ P+S S V++S + ++L
Sbjct: 26637 PAFISQPRSQ-NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLE 26695
Query: 320 IADVQPEDFGNYSCVADNSLGR 341
I + D G Y+ A N G+
Sbjct: 26696 IRNASVSDSGKYTIKAKNFRGQ 26717
Score = 46.0 bits (104), Expect = 3e-04
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 2/82 (2%)
Query: 275 GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCV 334
G + EL TV P +++W + L +R+T+ T+ I D + D G Y
Sbjct: 7208 GTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIE 7267
Query: 335 ADNSLGRARRHVEVS--GRPGP 354
A N GRA VEV+ +PGP
Sbjct: 7268 AVNVCGRATAVVEVNVLDKPGP 7289
Score = 45.6 bits (103), Expect = 4e-04
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTM--SARGSNHT 317
PP E + +G A TV+ +P V+W++ + L S T+ + GS T
Sbjct: 3574 PPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSG-T 3632
Query: 318 LLIADVQPEDFGNYSCVADNSLGRA 342
++ D Q ED G Y C A+N LG +
Sbjct: 3633 FIVNDPQREDSGLYICKAENMLGES 3657
Score = 45.6 bits (103), Expect = 4e-04
Identities = 47/181 (25%), Positives = 72/181 (39%), Gaps = 22/181 (12%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
E L + P VSW + PL+ RV++ + N TL++ D Q D G Y+
Sbjct: 13499 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTI 13558
Query: 334 VADNSLG--RARRHVEVSGRP----GPARFTSPPLARAPHSYTLSFAVDSYPPLDELRLL 387
N G ++V G+P GP +F + TL +A PP D+
Sbjct: 13559 TLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEV----TAEAMTLKWA----PPKDDGGSE 13610
Query: 388 YRQLAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWN 447
+ + +W V A A + T RV+ G++ Y V A+N+YG
Sbjct: 13611 ITNYILEKRDSVNNKW---VTCASAVQ-KTTFRVTRLHEGME----YTFRVSAENKYGVG 13662
Query: 448 E 448
E
Sbjct: 13663 E 13663
Score = 45.6 bits (103), Expect = 4e-04
Identities = 32/108 (29%), Positives = 46/108 (42%), Gaps = 3/108 (2%)
Query: 250 VTEFQLQVLYPPEI-TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVT 308
VT L+VL ++ T+ + +H G ELV + PP SW+ L SERVT
Sbjct: 23230 VTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVT 23289
Query: 309 MSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV--SGRPGP 354
+ L I + D G Y+ N G ++V +PGP
Sbjct: 23290 VETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGP 23337
Score = 44.4 bits (100), Expect = 0.001
Identities = 23/75 (30%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 262 EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIA 321
E E + E + EL C +++ E WY N L ++ + T+++R L +
Sbjct: 2222 EFVKELQDIEVPESYSGELEC-IVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVK 2280
Query: 322 DVQPEDFGNYSCVAD 336
DV ED G YS V D
Sbjct: 2281 DVTKEDQGEYSFVID 2295
Score = 44.4 bits (100), Expect = 0.001
Identities = 21/64 (32%), Positives = 33/64 (51%)
Query: 278 AELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADN 337
A L TV+ P ++ W+ N L+ S G +H+L+I + ED G Y+C+A N
Sbjct: 3474 ATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASN 3533
Query: 338 SLGR 341
G+
Sbjct: 3534 DYGK 3537
Score = 44.4 bits (100), Expect = 0.001
Identities = 36/145 (24%), Positives = 61/145 (42%), Gaps = 11/145 (7%)
Query: 237 YACTVDNGVGPP--VVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSW 294
YAC V++ V E ++++ PP+ +E F AEL EV W
Sbjct: 6395 YACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVV--FLAEL-----NKDKVEVQW 6447
Query: 295 YQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
+N+ + ++ M + G H L I D++P D G Y +A + RA+ +E++ P
Sbjct: 6448 LRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAK--LELAAAPKI 6505
Query: 355 ARFTSPPLARAPHSYTLSFAVDSYP 379
+ T+ D+YP
Sbjct: 6506 KTADQDLVVDVGKPLTMVVPYDAYP 6530
Score = 44.4 bits (100), Expect = 0.001
Identities = 60/268 (22%), Positives = 104/268 (38%), Gaps = 26/268 (9%)
Query: 189 GGAAVLECRAAGNPVPTVTWHRLNDSSSRLG--EGPQLQLSRLERHHGGVYACTVDNGVG 246
GG+ ++ +P W R N + ++ E L ++ A T N +
Sbjct: 12720 GGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVN-IS 12778
Query: 247 PPVVTEFQLQVL---YPPEITVE---RSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFP 300
PP + +L PP I + +S + G L TV P VSW ++
Sbjct: 12779 PPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTL 12838
Query: 301 LSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG--RARRHVEVSGRPGPARFT 358
L +E + M+ + + TL + V +D G+Y+ A+NS G A ++V +PGP
Sbjct: 12839 LKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGP---- 12894
Query: 359 SPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHDVVLAAPAAKGSLT 418
P + Y+ + PPL++ +++ W V P S+
Sbjct: 12895 -PASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVE 12953
Query: 419 HRV-SHELRGLQPAAVYEAIVQAKNRYG 445
+ HE Y+ + A+N+YG
Sbjct: 12954 KLIEGHE---------YQFRICAENKYG 12972
Score = 44.0 bits (99), Expect = 0.001
Identities = 25/84 (29%), Positives = 33/84 (39%)
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
+ P IT+ G + V + P AEV WY N L S ++ + TL
Sbjct: 25875 HAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTL 25934
Query: 319 LIADVQPEDFGNYSCVADNSLGRA 342
I D +D G Y V N G A
Sbjct: 25935 EILDCHTDDSGTYRAVCTNYKGEA 25958
Score = 43.6 bits (98), Expect = 0.002
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 270 VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFG 329
V GE + ++ + P V+W++++ PL + RV + +N L I D ED G
Sbjct: 15662 VLAGEDLKVDV--PFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVG 15719
Query: 330 NYSCVADNSLGRA--RRHVEVSGRPGP 354
+Y NS G A +V V +PGP
Sbjct: 15720 HYVVKLTNSAGEAIETLNVIVLDKPGP 15746
Score = 42.7 bits (96), Expect = 0.003
Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P I +E + EG + + A P VSW+++ + AS+R+TM + L +
Sbjct: 7890 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 7949
Query: 321 ADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPAR 356
D G Y+ +N LG A +V+V G PGP +
Sbjct: 7950 PKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCK 7987
Score = 42.3 bits (95), Expect = 0.004
Identities = 26/94 (27%), Positives = 41/94 (43%)
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
+L ++ P VE T F + L+ A V WY+N + ++ G
Sbjct: 6318 ELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDG 6377
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE 347
S H L+I D + +D Y+C ++ RAR VE
Sbjct: 6378 SIHRLIIKDCRLDDECEYACGVEDRKSRARLFVE 6411
Score = 41.1 bits (92), Expect = 0.009
Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 4/107 (3%)
Query: 250 VTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTM 309
V E + Q+L P + E+ + G+ R E V P W + + S + +
Sbjct: 12393 VYEAKEQLLPPKILMPEQITIKAGKKLRIE--AHVYGKPHPTCKWKKGEDEVVTSSHLAV 12450
Query: 310 SARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE--VSGRPGP 354
S+ L+I DV +D G YS A+NS G + ++ V PGP
Sbjct: 12451 HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGP 12497
Score = 40.7 bits (91), Expect = 0.012
Identities = 26/97 (26%), Positives = 44/97 (45%), Gaps = 5/97 (5%)
Query: 237 YACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ 296
Y+C V ++T + + ++ T + + E +LVC V + P AEV WY+
Sbjct: 5946 YSCEVRTARTSGMLTVLEEEAVF----TKNLANIEVSETDTIKLVCEV-SKPGAEVIWYK 6000
Query: 297 NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
+ + R + G L+I + ED GNY+C
Sbjct: 6001 GDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNC 6037
Score = 40.7 bits (91), Expect = 0.012
Identities = 35/137 (25%), Positives = 53/137 (38%), Gaps = 14/137 (10%)
Query: 162 DQVHTVEVLVPPSVRASPETR-HVTARRGGAAVLECRAAGNPVPTVTWHR--------LN 212
+ V ++L P + R V A+ G + G P PTVTW +
Sbjct: 20761 EPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDAR 20820
Query: 213 DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHT 272
S L + ++ R+ G Y T++NGVG P + ++VL P + H
Sbjct: 20821 YSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHV 20880
Query: 273 GEGFRAELVCTVLADPP 289
G T+L DPP
Sbjct: 20881 SRG-----TVTLLWDPP 20892
Score = 40.3 bits (90), Expect = 0.015
Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 251 TEFQLQVLYPP-EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTM 309
T L V PP E T EG A L C V + A+V W++N + S++ +
Sbjct: 5777 THANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSREN-AKVKWFKNGTEILKSKKYEI 5835
Query: 310 SARGSNHTLLIADVQPEDFGNYSCVA 335
A G L+I D PED Y+C A
Sbjct: 5836 VADGRVRKLVIHDCTPEDIKTYTCDA 5861
Score = 40.3 bits (90), Expect = 0.015
Identities = 50/220 (22%), Positives = 82/220 (37%), Gaps = 23/220 (10%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D +Y C + DR +R ++ E+ P + P+ GA V+ V
Sbjct: 6391 DECEYACGVEDRKSRARLFVEEI--PVEIIRPPQD---ILEAPGADVVFLAELNKDKVEV 6445
Query: 207 TWHRLN------DSSSRLGEGP--QLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVL 258
W R N D + EG +LQ+ ++ G Y + +L++
Sbjct: 6446 QWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRF-----IAKDKEARAKLELA 6500
Query: 259 YPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTL 318
P+I + G +V A P AE W++ + PLS T+ +
Sbjct: 6501 AAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK---TIDTTAEQTSF 6557
Query: 319 LIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPAR 356
I + + D G Y V N G+A +++V PGP R
Sbjct: 6558 RILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVR 6597
Score = 40.3 bits (90), Expect = 0.015
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 9/102 (8%)
Query: 260 PPEITVERSW-----VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
PP I+++ + VH GE F+ + + P + W + LS + R+ + +
Sbjct: 16043 PPRISMDPKYKDTIVVHAGESFKVD--ADIYGKPIPTIQWIKGDQELSNTARLEIKSTDF 16100
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGR--ARRHVEVSGRPGP 354
+L + D D GNY A N G +V+V RPGP
Sbjct: 16101 ATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP 16142
Score = 39.9 bits (89), Expect = 0.020
Identities = 43/166 (25%), Positives = 65/166 (39%), Gaps = 15/166 (9%)
Query: 288 PPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE 347
P A V+W ++ L + RV +S+ + +L I + ED G Y NS G +
Sbjct: 18925 PQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPIT 18984
Query: 348 --VSGRPGPARFTSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLAINESFQQPGRWHD 405
V RPGP P R S + PP + + + WH
Sbjct: 18985 IIVLDRPGP-----PGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWH- 19038
Query: 406 VVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVSD 451
+V A A R S ++ L + Y+ V A+NRYG + S+
Sbjct: 19039 IVSQAVA-------RTSIKIVRLTTGSEYQFRVCAENRYGKSSYSE 19077
Score = 39.5 bits (88), Expect = 0.027
Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 8/112 (7%)
Query: 248 PVVTEFQLQVLYPPEITVERSWVHT---GEGFRAELVCTVLADPPAEVSWYQNSFPLSAS 304
PV+ + QL+ PPEI ++ HT G ++ + P +V+ ++ PL A+
Sbjct: 19967 PVLIKEQLE---PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKAT 20023
Query: 305 ERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG--RARRHVEVSGRPGP 354
R N T+ + + D G Y A NS G +A ++ V RPGP
Sbjct: 20024 MRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGP 20075
Score = 39.1 bits (87), Expect = 0.035
Identities = 31/120 (25%), Positives = 49/120 (40%), Gaps = 5/120 (4%)
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
G ++ R E HG T V PV ++ V PP + V EG L
Sbjct: 862 GTTVREERFEVLHGREAKVTETARVPAPV----EIPVT-PPTLVSGLKNVTVIEGESVTL 916
Query: 281 VCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
C + P V+WY+ + + +S ++ + L+I + ED G ++C A N G
Sbjct: 917 ECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAG 976
Score = 39.1 bits (87), Expect = 0.035
Identities = 42/172 (24%), Positives = 68/172 (39%), Gaps = 12/172 (6%)
Query: 193 VLECRAAGNPVPTVTWHRLN-DSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVT 251
V+EC+ G T W+R+N D R L + + A + P +
Sbjct: 11342 VVECQKPG----TAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELA 11397
Query: 252 EFQL--QVLYPPEITVE---RSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASER 306
E + +L+PPE+ ++ R + G ++ V P +++W + L +R
Sbjct: 11398 ESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR 11457
Query: 307 VTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRH--VEVSGRPGPAR 356
V + L I + D G Y A NS G A+ V V RPGP +
Sbjct: 11458 VDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQ 11509
Score = 38.7 bits (86), Expect = 0.047
Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHR 210
VE+ V P S ++VT G + LEC +G P PTVTW+R
Sbjct: 890 VEIPVTPPTLVSG-LKNVTVIEGESVTLECHISGYPSPTVTWYR 932
Score = 38.7 bits (86), Expect = 0.047
Identities = 32/113 (28%), Positives = 49/113 (43%), Gaps = 8/113 (7%)
Query: 273 GEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYS 332
GE FR E V PP + W ++ L + ++ + + L+ D D G Y+
Sbjct: 14979 GEAFRLE--ADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYT 15036
Query: 333 CVADNSLGRARR--HVEVSGRPGPARFTSPPLARAPHSYTLSFAVDSYPPLDE 383
A N G A+ +V+V RPGP PLA + + +PPLD+
Sbjct: 15037 LTATNPGGFAKHIFNVKVLDRPGP---PEGPLA-VTEVTSEKCVLSWFPPLDD 15085
Score = 38.7 bits (86), Expect = 0.047
Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 6/89 (6%)
Query: 275 GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCV 334
G L P +SW ++ PL SE V S + TL I + + E G Y+ +
Sbjct: 21081 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 21140
Query: 335 ADNSLGRARRHVEV--SGRP----GPARF 357
DN++ R + V G P GP RF
Sbjct: 21141 LDNAVCRIAVPITVITLGPPSKPKGPIRF 21169
Score = 38.3 bits (85), Expect = 0.062
Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
Query: 277 RAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVAD 336
RA C V ++P V W ++ L ++R+ + H LLI + D G Y+ VA
Sbjct: 3028 RAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAG 3086
Query: 337 NSLGRARRHVE 347
++ A+ VE
Sbjct: 3087 GNVSTAKLFVE 3097
Score = 37.9 bits (84), Expect = 0.082
Identities = 26/110 (23%), Positives = 44/110 (40%), Gaps = 3/110 (2%)
Query: 233 HGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSW--VHTGEGFRAELVCTVLADPPA 290
H G Y C N G T +L V+ ++R + G A+ C + + P
Sbjct: 4308 HQGEYVCEALNDSGK-TATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNV 4366
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
W++ + S++ ++ + +L I Q D G Y+C A N G
Sbjct: 4367 RFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYG 4416
Score = 37.9 bits (84), Expect = 0.082
Identities = 21/69 (30%), Positives = 30/69 (43%), Gaps = 4/69 (5%)
Query: 292 VSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR 351
V WY L S++V + G HTL + DV+ ED G A + + H + +
Sbjct: 5729 VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD----FKTHANLFVK 5784
Query: 352 PGPARFTSP 360
P FT P
Sbjct: 5785 EPPVEFTKP 5793
Score = 37.9 bits (84), Expect = 0.082
Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNH--T 317
PP+I S + EG + C +P EV+W + + E+ ++ T
Sbjct: 26831 PPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTT 26890
Query: 318 LLIADVQPEDFGNYSCVADNSLG 340
L+I DVQ +D G Y+ N G
Sbjct: 26891 LIIMDVQKQDGGLYTLSLGNEFG 26913
Score = 37.1 bits (82), Expect = 0.14
Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 1/88 (1%)
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P+I + V EG A C V P +V+WY N + S+R + G H L I
Sbjct: 1795 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGI-HYLDI 1853
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEV 348
D + D G A+N G V++
Sbjct: 1854 VDCKSYDTGEVKVTAENPEGVIEHKVKL 1881
Score = 37.1 bits (82), Expect = 0.14
Identities = 20/77 (25%), Positives = 31/77 (40%)
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT 317
+Y ++ V+ EG +A L C V V WY N + +RV +G+
Sbjct: 2396 VYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQR 2455
Query: 318 LLIADVQPEDFGNYSCV 334
L+I D G Y +
Sbjct: 2456 LVINRTHASDEGPYKLI 2472
Score = 36.7 bits (81), Expect = 0.19
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 9/100 (9%)
Query: 155 ISDRVARDQVHTVEVLVPPSVRASP-ETRHVTARRGGAAVLECRAAGNPVPTVTWHR--- 210
+SD V + E+++ P V S VT R G LE G P P+++W +
Sbjct: 21046 LSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGL 21105
Query: 211 -LNDSS----SRLGEGPQLQLSRLERHHGGVYACTVDNGV 245
L +S S+ L + ++ HGG Y +DN V
Sbjct: 21106 PLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAV 21145
Score = 36.3 bits (80), Expect = 0.25
Identities = 21/69 (30%), Positives = 31/69 (44%), Gaps = 2/69 (2%)
Query: 288 PPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE 347
P +V+W L ++RV+++ TL + D D G Y +N+ G V
Sbjct: 22178 PAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVT 22237
Query: 348 --VSGRPGP 354
V GRPGP
Sbjct: 22238 VVVIGRPGP 22246
Score = 35.9 bits (79), Expect = 0.33
Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 3/93 (3%)
Query: 252 EFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPL--SASERVTM 309
E QL+ LY P ++ EG V+ P E W+ + + + +V +
Sbjct: 1402 ESQLERLYKPVFVLKPVSFKCLEGANCRFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVI 1461
Query: 310 SARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
G+ +L+I P D G ++ VA N GR+
Sbjct: 1462 KEDGTQ-SLIIVPATPSDSGEWTVVAQNRAGRS 1493
Score = 35.9 bits (79), Expect = 0.33
Identities = 51/202 (25%), Positives = 82/202 (40%), Gaps = 23/202 (11%)
Query: 258 LYPPEITVE---RSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGS 314
L PP + ++ + + GE F L P +VSW+++ + +R + +
Sbjct: 10318 LAPPTLHLDFRDKLTIRVGEAFA--LTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPA 10375
Query: 315 NHTLLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTSPPLARAPHSYTLS 372
L + D G Y V +NS G + V V PGP P + T
Sbjct: 10376 TLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDHPGP-----PVGPVSFDEVTKD 10430
Query: 373 FAVDSY-PPLDELRLLYRQLAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPA 431
+ V S+ PPLD+ I + ++ G+ DV + +A T +VS L G
Sbjct: 10431 YMVISWKPPLDDGGSKITNYIIEK--KEVGK--DVWMPVTSASAKTTCKVSKLLEGKD-- 10484
Query: 432 AVYEAIVQAKNRYGWNE--VSD 451
Y + A+N YG ++ VSD
Sbjct: 10485 --YIFRIHAENLYGISDPLVSD 10504
Score = 35.9 bits (79), Expect = 0.33
Identities = 64/292 (21%), Positives = 110/292 (37%), Gaps = 34/292 (11%)
Query: 90 DVGPQIRYTVDVTIYENSET-----SVALAILGATGHTNVWETTRR--ITSEQHGNTNFR 142
D Q+ + V ENSE +AIL T + + T R + ++ ++++
Sbjct: 25098 DQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA 25157
Query: 143 MIF----QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRA 198
+F ++ DY C+ + + + + T+ +L P P + TA G
Sbjct: 25158 ELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLP-LYNKTAYVGENVRFGVTI 25216
Query: 199 AGNPVPTVTWHRL--------NDSSSRLGEGP---QLQLSRLERHHGGVYACTVDNGVGP 247
+P P VTW++ ND QL ++ + Y N G
Sbjct: 25217 TVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGE 25276
Query: 248 PVVTEFQLQVLYPP--EITVE---RSWVHTGEGFRAELVC---TVLADPPAEVSWYQNSF 299
L+PP + T+ + + E + VC V PP + W ++
Sbjct: 25277 DSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQ 25336
Query: 300 PLSASERVTMSARGSNHTLL-IADVQPEDFGNYSCVADNSLG--RARRHVEV 348
PLS + + G ++ L I D PED G Y A N+ G + H++V
Sbjct: 25337 PLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25388
Score = 35.5 bits (78), Expect = 0.44
Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
EG +AE VC++ + V W ++ L + ++ + A G L++ D +D G Y
Sbjct: 6068 EGEKAEFVCSISKES-FPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTY-- 6124
Query: 334 VADNSLGRARRHVEV 348
V RA H+ V
Sbjct: 6125 VVMVGAARAAAHLTV 6139
Score = 35.5 bits (78), Expect = 0.44
Identities = 33/124 (26%), Positives = 47/124 (37%), Gaps = 8/124 (6%)
Query: 244 GVGPPVVTE--FQLQVLYPPEITVE---RSWVHTGEGFRAELVCTVLADPPAEVSWYQNS 298
G GPP T+ + PP + ++ + + G + V P W +
Sbjct: 8586 GEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEE 8645
Query: 299 FPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGR--ARRHVEVSGRPGPAR 356
L +RV + G+ L+I D +D G Y A NS G A VEV PGP
Sbjct: 8646 GELD-KDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVL 8704
Query: 357 FTSP 360
P
Sbjct: 8705 DLKP 8708
Score = 35.5 bits (78), Expect = 0.44
Identities = 40/178 (22%), Positives = 71/178 (39%), Gaps = 16/178 (8%)
Query: 270 VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFG 329
V G+ + E+ + P ++W ++ PL + R+ ++ TL I + +D G
Sbjct: 16744 VQVGQDLKMEV--PISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGG 16801
Query: 330 NYSCVADNSLGRARRHVEV--SGRPGPARFTSPPLARAPHSYTLSFAVDSYPPLDELRLL 387
Y N +G+ +E+ +P P + + S TLS+ PPL
Sbjct: 16802 QYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSW----NPPLYTGGCQ 16857
Query: 388 YRQLAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYG 445
+ + W DVV A A R + ++ L+ Y+ + A+NRYG
Sbjct: 16858 ITNYIVQKRDTTTTVW-DVVSATVA-------RTTLKVTKLKTGTEYQFRIFAENRYG 16907
Score = 35.1 bits (77), Expect = 0.58
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 1/70 (1%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMS-ARGSNHTLLIADVQPEDFGNYS 332
EG C + P +++WY++ + ER M + +L I V PED G Y+
Sbjct: 1258 EGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYT 1317
Query: 333 CVADNSLGRA 342
A N G A
Sbjct: 1318 AFASNIKGNA 1327
Score = 35.1 bits (77), Expect = 0.58
Identities = 26/106 (24%), Positives = 45/106 (42%), Gaps = 6/106 (5%)
Query: 244 GVGPPVVTEFQLQ---VLYPPEITVE---RSWVHTGEGFRAELVCTVLADPPAEVSWYQN 297
G G P+ +Q +L PEI ++ R+ V G +++ PP V+W ++
Sbjct: 20752 GQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKD 20811
Query: 298 SFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRAR 343
L + R ++ S+ L I V D G Y +N +G +
Sbjct: 20812 EKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPK 20857
Score = 34.7 bits (76), Expect = 0.76
Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 1/74 (1%)
Query: 273 GEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSN-HTLLIADVQPEDFGNY 331
G+G A V+ P E WY+N + S+R+ N L+I DV ED +
Sbjct: 2044 GQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASI 2103
Query: 332 SCVADNSLGRARRH 345
A N G H
Sbjct: 2104 MVKAINIAGETSSH 2117
Score = 34.7 bits (76), Expect = 0.76
Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Query: 283 TVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
++L P + SW + + S+ +++ ++ L I +D G Y+ A N G
Sbjct: 13905 SILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTK 13964
Query: 343 RRHVEVS-----GRPGPARFTSPPLARAPHSYT 370
HV+V+ G PGP ++ +A ++T
Sbjct: 13965 VEHVKVTVLDVPGPPGPVEISNVSAEKATLTWT 13997
Score = 34.7 bits (76), Expect = 0.76
Identities = 40/173 (23%), Positives = 68/173 (39%), Gaps = 12/173 (6%)
Query: 273 GEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYS 332
G+ + E+ VL P V+W + L ++RV ++ L I + D G Y
Sbjct: 14583 GDNIKVEI--PVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYP 14640
Query: 333 CVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTLSFAVDSYPPLDELRLLYRQLA 392
A N +G + + P T P S ++F+ D PP ++ +
Sbjct: 14641 LTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWD--PPENDGGVPISNYV 14698
Query: 393 INESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYG 445
+ W V LA + T++ + GL+ Y+ V+A+NRYG
Sbjct: 14699 VEMRQTDSTTW--VELATTVIR--TTYKATRLTTGLE----YQFRVKAQNRYG 14743
Score = 33.9 bits (74), Expect = 1.3
Identities = 29/110 (26%), Positives = 48/110 (43%), Gaps = 12/110 (10%)
Query: 162 DQVHTVEVLVPPSVRASPETRHV-TARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGE 220
D V + VPP + S + + T + G L+ G P+PTV+W + + + + E
Sbjct: 12785 DPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKK-DGTLLKPAE 12843
Query: 221 GPQLQLSR---------LERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP 261
G ++ + R + R G Y T +N G T +L+VL P
Sbjct: 12844 GIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSAT-IKLKVLDKP 12892
Score = 33.9 bits (74), Expect = 1.3
Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 4/82 (4%)
Query: 275 GFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCV 334
G L+ +V PP ++W + L++ R + S L++ V D G Y+
Sbjct: 22964 GASLRLMVSVSGRPPPVITWSKQGIDLAS--RAIIDTTESYSLLIVDKVNRYDAGKYTIE 23021
Query: 335 ADNSLGR--ARRHVEVSGRPGP 354
A+N G+ A V+V PGP
Sbjct: 23022 AENQSGKKSATVLVKVYDTPGP 23043
Score = 33.9 bits (74), Expect = 1.3
Identities = 20/76 (26%), Positives = 31/76 (40%), Gaps = 1/76 (1%)
Query: 274 EGFRAELVCTVLA-DPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYS 332
EG + VC + D +V+WY L SE+ ++ L + D+ D G Y
Sbjct: 25084 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 25143
Query: 333 CVADNSLGRARRHVEV 348
C N G + E+
Sbjct: 25144 CKVVNDYGEDSSYAEL 25159
Score = 33.9 bits (74), Expect = 1.3
Identities = 16/56 (28%), Positives = 27/56 (48%)
Query: 155 ISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHR 210
+ ++ ++ T ++ + R + R +T G +A C G PVPTVTW R
Sbjct: 26044 LEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 26099
Score = 33.5 bits (73), Expect = 1.8
Identities = 14/56 (25%), Positives = 27/56 (48%)
Query: 292 VSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVE 347
V W+ S + S++ + + H L++ ++ P D G Y+ V +A+ VE
Sbjct: 2779 VKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLFVE 2834
Score = 33.5 bits (73), Expect = 1.8
Identities = 46/193 (23%), Positives = 73/193 (37%), Gaps = 23/193 (11%)
Query: 263 ITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSF----PLSASE--RVTMSARGSNH 316
++V + G + V P ++ W +N P A + + +S +
Sbjct: 8904 LSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKT 8963
Query: 317 TLLIADVQPEDFGNYSCVADNSLGRARR--HVEVSGRPGPARFTSPPLARAPHSYTLSFA 374
L I ED G Y+ A N LG R HVEV RP P R + +A Y A
Sbjct: 8964 ELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDA 9023
Query: 375 VDSYPPLDE--LRLLYRQLAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAA 432
PLD + + + ++ ++ W +V A + + + L P
Sbjct: 9024 -----PLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKR--------YGIWKLIPNG 9070
Query: 433 VYEAIVQAKNRYG 445
YE V+A N+YG
Sbjct: 9071 QYEFRVRAVNKYG 9083
Score = 33.5 bits (73), Expect = 1.8
Identities = 22/90 (24%), Positives = 41/90 (45%), Gaps = 4/90 (4%)
Query: 121 HTNVWETTRRITS-EQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASP 179
+TN+ ET +T + FR+ ++A D V + S+ + + + PP V
Sbjct: 19239 YTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTG--PIIVKDDVEPPRVMMDV 19296
Query: 180 ETRHVTARRGGAAV-LECRAAGNPVPTVTW 208
+ R V + G + + AG P+P ++W
Sbjct: 19297 KFRDVIVVKAGEVLKINADIAGRPLPVISW 19326
Score = 33.5 bits (73), Expect = 1.8
Identities = 43/196 (21%), Positives = 78/196 (39%), Gaps = 21/196 (10%)
Query: 180 ETRHVTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQLSRLE-RHHGGVYA 238
E R++ R A L C+ G+P P V W+R + +G + ++ + +H + A
Sbjct: 24436 ELRNLNVRYQSNATLVCKVTGHPKPIVKWYR--QGKEIIADGLKYRIQEFKGGYHQLIIA 24493
Query: 239 CTVDNGV----------GPPVVTEFQLQVLYPPEITVERSWVHTG--EGFRAELVCTVL- 285
D+ G V L+V P +I + ++ G R E+V +
Sbjct: 24494 SVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIP 24553
Query: 286 --ADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIAD-VQPEDFGNYSCVADNSLGRA 342
P ++W + + + + S +L+ + V+ +D G Y A N G
Sbjct: 24554 FSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGID 24613
Query: 343 RRHVE--VSGRPGPAR 356
++ VE V+ P P R
Sbjct: 24614 QKTVELDVADVPDPPR 24629
Score = 33.1 bits (72), Expect = 2.3
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 7/84 (8%)
Query: 170 LVPPSVRASPETRH-VTARRGGAAVLECRAAGNPVPTVTWHRLNDSSS---RLGEG---P 222
L P + E R + R GG+A + G P+P +TW R + ++ +G
Sbjct: 17522 LEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPMPEITWSREEGEFTDKVQIEKGVNYT 17581
Query: 223 QLQLSRLERHHGGVYACTVDNGVG 246
QL + +R+ G Y ++N G
Sbjct: 17582 QLSIDNCDRNDAGKYILKLENSSG 17605
Score = 32.7 bits (71), Expect = 3.1
Identities = 15/39 (38%), Positives = 22/39 (56%)
Query: 294 WYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYS 332
W ++ + S+RV + +H LLI D+ ED GNYS
Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYS 2380
Score = 32.7 bits (71), Expect = 3.1
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPED 327
EG A VC L+ V W++N L S V +S+ G H L + +V +D
Sbjct: 5090 EGETATFVCE-LSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDD 5142
Score = 32.7 bits (71), Expect = 3.1
Identities = 22/93 (23%), Positives = 37/93 (39%), Gaps = 9/93 (9%)
Query: 162 DQVHTVEVLVPPSVRASPETR-HVTARRGGAAVLECRAAGNPVPTVTWHRLNDSS----- 215
D + + LV P ++ R + GG + +G P PTVTW+ +N+ +
Sbjct: 10014 DVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWN-MNERTLPQEA 10072
Query: 216 --SRLGEGPQLQLSRLERHHGGVYACTVDNGVG 246
+ + +R H GVY+ N G
Sbjct: 10073 TIETTAISSSMVIKNCQRSHQGVYSLLAKNEAG 10105
Score = 32.7 bits (71), Expect = 3.1
Identities = 25/98 (25%), Positives = 39/98 (39%), Gaps = 8/98 (8%)
Query: 161 RDQVHTVEVLVPPSVRASPETRHVTARRGGAAV-LECRAAGNPVPTVTWHRLN-DSSSRL 218
++ + E+L PP + R + R G + L G P P VTW ++ D+ R
Sbjct: 12095 KEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRK 12154
Query: 219 GEGPQ------LQLSRLERHHGGVYACTVDNGVGPPVV 250
G+ L + R G Y+ T+ N G V
Sbjct: 12155 GQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAV 12192
Score = 32.7 bits (71), Expect = 3.1
Identities = 26/105 (24%), Positives = 42/105 (40%), Gaps = 8/105 (7%)
Query: 164 VHTVEVLVPPSVRASPETRHVTARRGGAAV-LECRAAGNPVPTVTWHRLNDSSSRLGE-- 220
+ V+ L P + + R GA++ L G P PT W + + + S +
Sbjct: 21849 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIH 21908
Query: 221 ----GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP 261
L + R+ G Y TV+N G +T F ++VL P
Sbjct: 21909 TTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSIT-FTVKVLDTP 21952
Score = 32.7 bits (71), Expect = 3.1
Identities = 38/153 (24%), Positives = 59/153 (38%), Gaps = 16/153 (10%)
Query: 121 HTNVWETTRRITSEQHGNT-NFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASP 179
+T V + +T+ G+T FR++ ++A + + S+ V + PP
Sbjct: 22496 YTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTG--PVTCRDEYAPPKAELDA 22553
Query: 180 ETRH--VTARRGGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQ---------LSR 228
VT R G VL+ G P P + W + D L E LQ +
Sbjct: 22554 RLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTK-GDKELDLCEKVSLQYTGKRATAVIKF 22612
Query: 229 LERHHGGVYACTVDNGVGPPVVTEFQLQVLYPP 261
+R G Y TV N G V+ ++VL P
Sbjct: 22613 CDRSDSGKYTLTVKNASGTKAVS-VMVKVLDSP 22644
Score = 32.3 bits (70), Expect = 4.1
Identities = 15/71 (21%), Positives = 32/71 (45%), Gaps = 4/71 (5%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASP----ETRHVTARRGGAAVLECRAAGNP 202
D+G++ +R R + + + + P + ++V + G ++ RA GNP
Sbjct: 1478 DSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNP 1537
Query: 203 VPTVTWHRLND 213
P + W + +D
Sbjct: 1538 NPDIVWLKNSD 1548
Score = 32.3 bits (70), Expect = 4.1
Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 9/85 (10%)
Query: 170 LVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTWHR-----LNDSSSRLGEGP-- 222
L PP++ + +T R G A L R +G P P V+W + L D + + P
Sbjct: 10318 LAPPTLHLDFRDK-LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPAT 10376
Query: 223 -QLQLSRLERHHGGVYACTVDNGVG 246
L+ + +R G Y V+N G
Sbjct: 10377 LALEKIKAKRSDSGKYCVVVENSTG 10401
Score = 32.3 bits (70), Expect = 4.1
Identities = 32/134 (23%), Positives = 55/134 (41%), Gaps = 11/134 (8%)
Query: 126 ETTRRITSEQHGNT-NFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPE-TRH 183
ET ++T + G T FR++ +A + + V + L PP + R
Sbjct: 10674 ETKYKVTGLRDGQTYKFRVLAVNAAG---ESDPAHVPEPVLVKDRLEPPELILDANMARE 10730
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRLGEGP---QLQLSRLERHHGGVY 237
+ G L G P P VTW + + + +R+ P +L++ GG+Y
Sbjct: 10731 QHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIY 10790
Query: 238 ACTVDNGVGPPVVT 251
+ TV+N G V+
Sbjct: 10791 SLTVENPAGSKTVS 10804
Score = 32.3 bits (70), Expect = 4.1
Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 162 DQVHTVEVLVPPSVRASPETRHVTARRGGAAV-LECRAAGNPVPTVTWHRLN-DSSSRLG 219
D+ + ++L+PP + R R G + L G P P +TW + N + R+G
Sbjct: 13183 DKHYPKDILIPPEGEHDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG 13242
Query: 220 EGPQ-------LQLSRLERHHGGVYACTVDNGVG 246
+ L+ + ++ G Y T++N G
Sbjct: 13243 LDIKSTDFDTFLRCENVNKYDAGKYILTLENSCG 13276
Score = 31.9 bits (69), Expect = 5.4
Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 10/94 (10%)
Query: 122 TNVWETTRRITS-EQHGNTNFRMIFQDAGDYVCQISDRV----ARDQVHTVEVLVPPSVR 176
TNV ET ++ + FR+I ++A + + SD A+D+V + + P R
Sbjct: 17076 TNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFR 17135
Query: 177 ASPETRHVTARRGGAAVLECRAAGNPVPTVTWHR 210
+ + G LE G P+PT+ W R
Sbjct: 17136 DT-----IVVNAGETFRLEADVHGKPLPTIEWLR 17164
Score = 31.9 bits (69), Expect = 5.4
Identities = 35/135 (25%), Positives = 54/135 (40%), Gaps = 12/135 (8%)
Query: 122 TNVWETTRRITSEQHGNT-NFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPE 180
T+V E +T G+ FR+I ++A + S + + T + VPP V PE
Sbjct: 21409 TDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQ--SSGIIMTRDENVPPIVEFGPE 21466
Query: 181 TRHVTARRGGAAV-LECRAAGNPVPTVTW--------HRLNDSSSRLGEGPQLQLSRLER 231
+ G ++ ++ G PVP VTW R+N + + L + R
Sbjct: 21467 YFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITNVLGSTSLFVRDATR 21526
Query: 232 HHGGVYACTVDNGVG 246
H GVY N G
Sbjct: 21527 DHRGVYTVEAKNASG 21541
Score = 31.9 bits (69), Expect = 5.4
Identities = 21/79 (26%), Positives = 30/79 (37%), Gaps = 2/79 (2%)
Query: 262 EITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIA 321
EI + + EG R L + +V W N L+ SE GS+ TL I
Sbjct: 26543 EIKAFSTQMSINEGQRLVLKANIAG--ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIK 26600
Query: 322 DVQPEDFGNYSCVADNSLG 340
D G +C++ G
Sbjct: 26601 QASHRDEGILTCISKTKEG 26619
Score = 31.5 bits (68), Expect = 7.1
Identities = 13/49 (26%), Positives = 24/49 (48%)
Query: 286 ADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCV 334
++P +V WY++ + ++ M + H L I + D +YSCV
Sbjct: 2153 SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCV 2201
Score = 31.5 bits (68), Expect = 7.1
Identities = 13/44 (29%), Positives = 21/44 (47%)
Query: 294 WYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADN 337
W +N + SE+ + +G H L+I + ED Y+ V N
Sbjct: 2868 WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN 2911
Score = 31.5 bits (68), Expect = 7.1
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 4/87 (4%)
Query: 270 VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFG 329
V+ GE FR E V P + W + + S R + L++ D D G
Sbjct: 17140 VNAGETFRLE--ADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGG 17197
Query: 330 NYSCVADNSLGRAR--RHVEVSGRPGP 354
Y A N G +V+V RPGP
Sbjct: 17198 QYILRASNVAGSKSFPVNVKVLDRPGP 17224
Score = 31.1 bits (67), Expect = 9.4
Identities = 28/99 (28%), Positives = 41/99 (41%), Gaps = 5/99 (5%)
Query: 254 QLQVLYP-PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSAR 312
QL+VL P TV+ E L C V D P V W+++ + S + ++ A
Sbjct: 5158 QLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIVPSPKYSIKAD 5215
Query: 313 GSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR 351
G L I +D G Y C D + + +V V R
Sbjct: 5216 GLRRILKIKKADLKDKGEYVC--DCGTDKTKANVTVEAR 5252
Score = 31.1 bits (67), Expect = 9.4
Identities = 51/228 (22%), Positives = 91/228 (39%), Gaps = 28/228 (12%)
Query: 229 LERHHGGVYACTVDN-GVGP------PVVTEFQLQVLYPPEITVE---RSWVHTGEGFRA 278
LE+H C ++ GVG P++ E +L+ P+I ++ R ++ G
Sbjct: 16407 LEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEA---PDIDLDLELRKIINIRAGGSL 16463
Query: 279 ELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNS 338
L + P EV W + + + + +++ S +L++ +V D G Y+ +NS
Sbjct: 16464 RLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS--SFTSLVLDNVNRYDSGKYTLTLENS 16521
Query: 339 LGRARRHVEVSGRPGPARFTSPPLARAPHSYTL-SFAVDSYPPLDELRLLYRQLAINESF 397
G V V P SPP+ T S ++ PPL + + + +
Sbjct: 16522 SGTKSAFVTVRVLDTP----SPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK-- 16575
Query: 398 QQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYG 445
+ + AA + H+ S ++ LQ Y V A+N YG
Sbjct: 16576 ------REATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYG 16617
Score = 31.1 bits (67), Expect = 9.4
Identities = 37/151 (24%), Positives = 63/151 (41%), Gaps = 14/151 (9%)
Query: 122 TNVWETTRRITS-EQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPE 180
TNV ET ++ + FR+I ++A + SD + + + + P+ P+
Sbjct: 18158 TNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSD--SSGAITARDEIDAPNASLDPK 18215
Query: 181 TRHVTARRGGAA-VLECRAAGNPVPTVTWHR----LNDSSSRLGEGPQLQLSRLE----- 230
+ V G VLE G P+P V W + L ++++R+ +Q + L
Sbjct: 18216 YKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCI 18275
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPP 261
R GG Y + N VG ++VL P
Sbjct: 18276 RTDGGQYILKLSN-VGGTKSIPITVKVLDRP 18305
Score = 31.1 bits (67), Expect = 9.4
Identities = 37/175 (21%), Positives = 68/175 (38%), Gaps = 10/175 (5%)
Query: 189 GGAAVLECRAAGNPVPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPP 248
GGA + +P W + N ++ + +L+ +R+ V+A + V P
Sbjct: 19215 GGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEP 19274
Query: 249 VVTEFQLQV---LYPPEITVE---RSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLS 302
+ + V + PP + ++ R + G ++ + P +SW ++ +
Sbjct: 19275 SESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE 19334
Query: 303 ASERVTMSARGSNHTLL-IADVQPEDFGNYSCVADNSLGRARRHV--EVSGRPGP 354
R + + NHTLL + D D G Y N G V +V +PGP
Sbjct: 19335 ERARTEIIST-DNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGP 19388
Score = 31.1 bits (67), Expect = 9.4
Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Query: 122 TNVWETTRRITS-EQHGNTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPE 180
TNV ET I+ Q+ FR+ ++A + S+ V + ++ P + E
Sbjct: 20323 TNVTETQFTISGLTQNSQYEFRVFARNAVGSISNPSEVVG--PITCIDSYGGPVIDLPLE 20380
Query: 181 TRHVTARRGGAAV-LECRAAGNPVPTVTWHR 210
V R G +V L +G P PT+ W++
Sbjct: 20381 YTEVVKYRAGTSVKLRAGISGKPAPTIEWYK 20411
>U55258-1|AAC50765.1| 1299|Homo sapiens hBRAVO/Nr-CAM precursor
protein.
Length = 1299
Score = 64.9 bits (151), Expect = 6e-10
Identities = 57/247 (23%), Positives = 98/247 (39%), Gaps = 19/247 (7%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+G+Y C + + HT+ V V + +++ G L CRA GNP P +
Sbjct: 329 DSGNYQCIAKNALGAIH-HTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRI 387
Query: 207 TW-------HRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
+W D SR +G + S ++ VY C N G + F +
Sbjct: 388 SWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAE 447
Query: 260 PPEITVERSWVHTGEGFRAELV-CTVLADPPAEVSWYQNSFPLSASERV-TMSARGS--- 314
PP I + ++ R L+ C P + W++ + + E + + G+
Sbjct: 448 PPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEI 507
Query: 315 -NHTLLIADV---QPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPL--ARAPHS 368
+ T ++ ++ Q + G Y+CVA N LG A+ V + + S + H
Sbjct: 508 KDATWIVKEIPVAQKDSTGTYTCVARNKLGMAKNEVHLQPEYAVVQRGSMVSFECKVKHD 567
Query: 369 YTLSFAV 375
+TLS V
Sbjct: 568 HTLSLTV 574
Score = 50.8 bits (116), Expect = 1e-05
Identities = 43/178 (24%), Positives = 66/178 (37%), Gaps = 7/178 (3%)
Query: 188 RGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLERHHGGVYACTVD 242
RG LEC A G P P + W + + + + LQ+ + G Y C
Sbjct: 279 RGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAK 338
Query: 243 NGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLS 302
N +G T P IT ++ V G L+C +P +SW N P+
Sbjct: 339 NALGAIHHTISVRVKAAPYWITAPQNLV-LSPGEDGTLICRANGNPKPRISWLTNGVPIE 397
Query: 303 ASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSP 360
+ S + T++ ++VQ Y C A N G + V+ P R +P
Sbjct: 398 IAPD-DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTP 454
Score = 47.2 bits (107), Expect = 1e-04
Identities = 67/266 (25%), Positives = 107/266 (40%), Gaps = 45/266 (16%)
Query: 167 VEVLV-PPSVRASPETRH-VTARRGGAAVLECRAAGNPVPTVTWHR------LNDSSSRL 218
V VL PP + T + V A R A+L+C G+P+PT+ W + L++ L
Sbjct: 442 VNVLAEPPRILTPANTLYQVIANR--PALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVL 499
Query: 219 GEGPQLQLSRL----------ERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERS 268
E L++ ++ G Y C N +G E LQ PE V +
Sbjct: 500 HENGTLEIKDATWIVKEIPVAQKDSTGTYTCVARNKLGM-AKNEVHLQ----PEYAVVQ- 553
Query: 269 WVHTGEGFRAELVCTVLADPPAEVS--WYQNSFPLSASERVTMSARGSNHTLLIADVQPE 326
G C V D ++ W +++ L + ER T+ +H L++ADV +
Sbjct: 554 -----RGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVD---KDH-LVVADVSDD 604
Query: 327 DFGNYSCVADNSLGRARRHVEVS-GRPGPARFTSPPLARAPHSYTLSFAVD-----SYPP 380
D G Y+CVA+ +L +S P P + P L+ +D S+ P
Sbjct: 605 DSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTP 664
Query: 381 LDELRLLYRQLAI--NESFQQPGRWH 404
D+ + I ++ +PG WH
Sbjct: 665 GDDNNSPITKFIIEYEDAMHKPGLWH 690
>AK131073-1|BAC85123.1| 659|Homo sapiens FLJ00259 protein protein.
Length = 659
Score = 64.9 bits (151), Expect = 6e-10
Identities = 55/174 (31%), Positives = 75/174 (43%), Gaps = 10/174 (5%)
Query: 180 ETRHVTARRGGAAVLECRAAGNPVPTVTWHR----LNDSSSRLGEGPQLQLSRLERHHGG 235
+ R V A G + CRA G P P + W R ++ +L L +SR+ GG
Sbjct: 430 QPRVVDASPGQRIRMTCRAEGFPPPAIEWQRDGQPVSSPRHQLQPDGSLVISRVAVEDGG 489
Query: 236 VYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWY 295
Y C NG QL+VL I+ V EG A L+C V+A + W
Sbjct: 490 FYTCVAFNGQDRD-QRWVQLRVLGELTISGLPPTVTVPEGDTARLLC-VVAGESVNIRWS 547
Query: 296 QNSFPLSA-SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
+N P+ A RV S G TLLI +++ D G+Y+C A R EV
Sbjct: 548 RNGLPVQADGHRVHQSPDG---TLLIYNLRARDEGSYTCSAYQGSQAVSRSTEV 598
Score = 37.1 bits (82), Expect = 0.14
Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 4/69 (5%)
Query: 265 VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQ 324
VE S V G L C+ P ++ +W ++ P+S S+R + GS L+I +Q
Sbjct: 295 VEPSLVQAALGQLVRLSCSDDTAPESQAAWQKDGQPIS-SDRHRLQFDGS---LIIHPLQ 350
Query: 325 PEDFGNYSC 333
ED G YSC
Sbjct: 351 AEDAGTYSC 359
>AF109907-3|AAC97963.1| 1235|Homo sapiens hypothetical protein
protein.
Length = 1235
Score = 64.9 bits (151), Expect = 6e-10
Identities = 55/174 (31%), Positives = 75/174 (43%), Gaps = 10/174 (5%)
Query: 180 ETRHVTARRGGAAVLECRAAGNPVPTVTWHR----LNDSSSRLGEGPQLQLSRLERHHGG 235
+ R V A G + CRA G P P + W R ++ +L L +SR+ GG
Sbjct: 1006 QPRVVDASPGQRIRMTCRAEGFPPPAIEWQRDGQPVSSPRHQLQPDGSLVISRVAVEDGG 1065
Query: 236 VYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWY 295
Y C NG QL+VL I+ V EG A L+C V+A + W
Sbjct: 1066 FYTCVAFNGQDRD-QRWVQLRVLGELTISGLPPTVTVPEGDTARLLC-VVAGESVNIRWS 1123
Query: 296 QNSFPLSA-SERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEV 348
+N P+ A RV S G TLLI +++ D G+Y+C A R EV
Sbjct: 1124 RNGLPVQADGHRVHQSPDG---TLLIYNLRARDEGSYTCSAYQGSQAVSRSTEV 1174
Score = 37.1 bits (82), Expect = 0.14
Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 4/69 (5%)
Query: 265 VERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQ 324
VE S V G L C+ P ++ +W ++ P+S S+R + GS L+I +Q
Sbjct: 852 VEPSLVQAALGQLVRLSCSDDTAPESQAAWQKDGQPIS-SDRHRLQFDGS---LIIHPLQ 907
Query: 325 PEDFGNYSC 333
ED G YSC
Sbjct: 908 AEDAGTYSC 916
>BC141884-1|AAI41885.1| 1688|Homo sapiens SIGLEC1 protein protein.
Length = 1688
Score = 64.5 bits (150), Expect = 8e-10
Identities = 63/217 (29%), Positives = 87/217 (40%), Gaps = 20/217 (9%)
Query: 142 RMIFQD--AGD--YVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECR 197
R+ QD AGD YVC + + + T+ L R E + G A L CR
Sbjct: 1410 RLQVQDVPAGDDTYVCTAQNLLG--SISTIGRLQVEGARVVAEPG-LDVPEGAALNLSCR 1466
Query: 198 AAGNPVP----TVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
G P P T W ND P L + + R G+Y C + G
Sbjct: 1467 LLGGPGPVGNSTFAWF-WNDRRLHAEPVPTLAFTHVARAQAGMYHCLAELPTGAAASAPV 1525
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
L+VLYPP+ +V G R L C V ++P A ++ + S +++S+ A
Sbjct: 1526 MLRVLYPPKTPTMMVFVEPEGGLRGILDCRVDSEPLASLTLHLGSRLVASSQPQGAPAEP 1585
Query: 314 SNHTL-----LIADVQ---PEDFGNYSCVADNSLGRA 342
H L L D++ P D G Y C A N LG A
Sbjct: 1586 HIHVLASPNALRVDIEALRPSDQGEYICSASNVLGSA 1622
Score = 62.1 bits (144), Expect = 4e-09
Identities = 64/208 (30%), Positives = 85/208 (40%), Gaps = 22/208 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNPV 203
+D G Y C S R Q +T L VR +PE G + C
Sbjct: 1234 RDEGFYSC--SARSPLGQANTSLELRLEGVRVILAPEA---AVPEGAPITVTCADPAAHA 1288
Query: 204 PTV-TWHRLNDSSSRLGEGPQLQLSRL--ERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
PT+ TW+ + L EGP LS L R H G Y+C + G LQVLY
Sbjct: 1289 PTLYTWYH---NGRWLQEGPAASLSFLVATRAHAGAYSCQAQDAQGTRSSRPAALQVLYA 1345
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT--- 317
P+ V S+ + A + CTV ++PPAE++ + L+ S V A G+ H
Sbjct: 1346 PQDAVLSSFRDSRARSMAVIQCTVDSEPPAELALSHDGKVLATSSGVHSLASGTGHVQVA 1405
Query: 318 -----LLIADVQPEDFGNYSCVADNSLG 340
L + DV P Y C A N LG
Sbjct: 1406 RNALRLQVQDV-PAGDDTYVCTAQNLLG 1432
Score = 53.2 bits (122), Expect = 2e-06
Identities = 59/249 (23%), Positives = 99/249 (39%), Gaps = 17/249 (6%)
Query: 144 IFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECR----AA 199
+ ++ G Y+C+ S+ + + +P H T + G A L C AA
Sbjct: 680 LLEEEGLYLCEASNALGNASTSATFNGQATVLAIAPS--H-TLQEGTEANLTCNVSREAA 736
Query: 200 GNPVPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
G+P +W R N G + L + R +YAC + G + T L VLY
Sbjct: 737 GSPA-NFSWFR-NGVLWAQGPLETVTLLPVARTDAALYACRILTEAGAQLSTPVLLSVLY 794
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS--------ERVTMSA 311
PP+ + + G+G A +CTV + P A ++ + L+ S R A
Sbjct: 795 PPDRPKLSALLDMGQGHMALFICTVDSRPLALLALFHGEHLLATSLGPQVPSHGRFQAKA 854
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTL 371
++ L + ++ D G+Y C A N LG + + R + + P + + L
Sbjct: 855 EANSLKLEVRELGLGDSGSYRCEATNVLGSSNTSLFFQVRGAWVQVSPSPELQEGQAVVL 914
Query: 372 SFAVDSYPP 380
S V + P
Sbjct: 915 SCQVPTGVP 923
Score = 51.2 bits (117), Expect = 8e-06
Identities = 54/208 (25%), Positives = 88/208 (42%), Gaps = 12/208 (5%)
Query: 144 IFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRA-AGNP 202
+ +D G Y+C+ S+ + + +V+ P T R G L C +P
Sbjct: 1058 MLEDEGVYICEASNTLGQASASADFDAQAVNVQVWPGA---TVREGQLVNLTCLVWTTHP 1114
Query: 203 VP-TVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDN-GVGPPVVTEFQLQVLYP 260
T TW++ D RL + + L + Y C V G P + L VLY
Sbjct: 1115 AQLTYTWYQ--DGQQRL-DAHSIPLPNVTVRDATSYRCGVGPPGRAPRLSRPITLDVLYA 1171
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P + + G A ++CTV + PPA+++ L++S T ++ + L +
Sbjct: 1172 PRNLRLTYLLESHGGQLALVLCTVDSRPPAQLALSHAGRLLASS---TAASVPNTLRLEL 1228
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEV 348
QP D G YSC A + LG+A +E+
Sbjct: 1229 RGPQPRDEGFYSCSARSPLGQANTSLEL 1256
Score = 46.8 bits (106), Expect = 2e-04
Identities = 53/211 (25%), Positives = 80/211 (37%), Gaps = 19/211 (9%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+G Y C+ ++ + + V+ SP + G A VL C+ VP
Sbjct: 870 DSGSYRCEATNVLGSSNTSLFFQVRGAWVQVSPSPE---LQEGQAVVLSCQVPTG-VPEG 925
Query: 207 TWHRLNDSSSRLGEGPQ--LQLSRLERHHGGVYACTVD--NGVGPPVVTEFQLQVLYPPE 262
T +R L E L+ + + G Y C + L V Y P
Sbjct: 926 TSYRWYRDGQPLQESTSATLRFAAITLTQAGAYHCQAQAPGSATTSLAVPISLHVSYAPR 985
Query: 263 ITVERSWVHTGEGFRAELVCTVLADPPAEV----------SWYQN-SFPLSASERVTMSA 311
+ + TG G L+C V +DPPA++ S Q P +S R+ ++
Sbjct: 986 HVTLTTLMDTGPGRLGLLLCRVDSDPPAQLRLLHGDRLVASTLQGVGGPEGSSPRLHVAV 1045
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+ L I ED G Y C A N+LG+A
Sbjct: 1046 APNTLRLEIHGAMLEDEGVYICEASNTLGQA 1076
Score = 45.6 bits (103), Expect = 4e-04
Identities = 55/210 (26%), Positives = 84/210 (40%), Gaps = 24/210 (11%)
Query: 143 MIFQDAGDYV-CQIS--DRVARDQVHTVEVLVPPSVRA--SPETRHVTARRGGAAVLECR 197
M +QD G + CQ+S + A+ ++H P V+ SP R++ G L C+
Sbjct: 206 MSWQDHGRILRCQLSMANHRAQSEIHLQVKYAPRGVKILLSPSGRNILP--GELVTLTCQ 263
Query: 198 AAGN--PVPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQL 255
+ V ++ W L D + L L + GVY C +NGVG V L
Sbjct: 264 VNSSYPAVSSIKW--LKDGVRLQTKTGVLHLPQAAWSDAGVYTCQAENGVGSLVSPPISL 321
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEV--SWYQNSFPLSASERVTMSARG 313
+ + E+ V + E LVC + P+++ SWY+N L +
Sbjct: 322 HI-FMAEVQVSPAGPIL-ENQTVTLVCNTPNEAPSDLRYSWYKNHVLLEDAH-------- 371
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRAR 343
+HTL + D G Y C N G R
Sbjct: 372 -SHTLRLHLATRADTGFYFCEVQNVHGSER 400
Score = 44.8 bits (101), Expect = 7e-04
Identities = 52/209 (24%), Positives = 84/209 (40%), Gaps = 16/209 (7%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEV-LVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
+ DAG Y CQ + V + + + V+ SP + + L C N
Sbjct: 297 WSDAGVYTCQAENGVGSLVSPPISLHIFMAEVQVSPAGPILENQ---TVTLVCNTP-NEA 352
Query: 204 PT---VTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
P+ +W++ N L+L R G Y C V N G + V +P
Sbjct: 353 PSDLRYSWYK-NHVLLEDAHSHTLRLHLATRADTGFYFCEVQNVHGSERSGPVSVVVNHP 411
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA-------SERVTMSARG 313
P V +++ T G L C+V+++P A + L++ S R + ++
Sbjct: 412 PLTPVLTAFLETQAGLVGILHCSVVSEPLATLVLSHGGHILASTSGDSDHSPRFSGTSGP 471
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRA 342
++ L I D++ D G Y C A NSLG A
Sbjct: 472 NSLRLEIRDLEETDSGEYKCSATNSLGNA 500
Score = 44.0 bits (99), Expect = 0.001
Identities = 59/230 (25%), Positives = 91/230 (39%), Gaps = 32/230 (13%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPS-VRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D+G+Y C ++ + + T++ + + SP V G A L CR+ +P P
Sbjct: 485 DSGEYKCSATNSLG-NATSTLDFHANAARLLISPAAEVV---EGQAVTLSCRSGLSPTPD 540
Query: 206 V--TWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNG---VGPPVVTEFQLQVLYP 260
+W+ LN + G G L L G Y C +G GP + L VLYP
Sbjct: 541 ARFSWY-LNGALLHEGPGSSLLLPAASSTDAGSYHCRARDGHSASGPS--SPAVLTVLYP 597
Query: 261 PE-----ITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ------NSFPL-------- 301
P ++ G G R L+C V +DPPA + S P
Sbjct: 598 PRQPTFTTRLDLDAAGAGAGRRGLLLCRVDSDPPARLQLLHKDRVVATSLPSGGGCSTCG 657
Query: 302 SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR 351
S R+ ++ + + I + E+ G Y C A N+LG A +G+
Sbjct: 658 GCSPRMKVTKAPNLLRVEIHNPLLEEEGLYLCEASNALGNASTSATFNGQ 707
>AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain
polypeptide kinase isoform 2 protein.
Length = 1845
Score = 64.5 bits (150), Expect = 8e-10
Identities = 55/203 (27%), Positives = 80/203 (39%), Gaps = 24/203 (11%)
Query: 193 VLECRAAGNPVPTVTW----HRLNDSSSRLGEG-PQLQLSRLERHHGGVYACTVDNGVGP 247
VL+C G PVP +TW + + S G +L + G Y C +N +G
Sbjct: 463 VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 522
Query: 248 PVVTEF----------QLQVLYP--------PEITVERSWVHTGEGFRAELVCTVLADPP 289
+ + + + L P P S + +G + + V +PP
Sbjct: 523 VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 582
Query: 290 AEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVS 349
EV W N + SE RG+ H+L I +V PED G Y+C A NS G R ++
Sbjct: 583 PEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLT 642
Query: 350 GRPGPARFTSPPLARAPHSYTLS 372
+ P T P P S T S
Sbjct: 643 VQE-PHDGTQPWFISKPRSVTAS 664
Score = 61.3 bits (142), Expect = 8e-09
Identities = 32/86 (37%), Positives = 44/86 (51%)
Query: 270 VHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFG 329
VH EG + L C V +DPPA + W N L ++ + +S GS ++ I PED G
Sbjct: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
Query: 330 NYSCVADNSLGRARRHVEVSGRPGPA 355
Y CVA N G+A +V+ PA
Sbjct: 1098 LYKCVAKNDAGQAECSCQVTVDDAPA 1123
Score = 54.8 bits (126), Expect = 7e-07
Identities = 27/90 (30%), Positives = 42/90 (46%)
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLL 319
PP+ + V EG C + P +V+W + + PL S RV++S + L
Sbjct: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
Query: 320 IADVQPEDFGNYSCVADNSLGRARRHVEVS 349
I V +D G Y+C+ N G+A E+S
Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELS 249
Score = 43.6 bits (98), Expect = 0.002
Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 3/68 (4%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSC 333
EG L C+V P ++W N P+ + + H I D PED G Y+C
Sbjct: 458 EGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH---IQDALPEDHGTYTC 514
Query: 334 VADNSLGR 341
+A+N+LG+
Sbjct: 515 LAENALGQ 522
Score = 41.1 bits (92), Expect = 0.009
Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA--RGSNHTLLIADVQPEDFGNY 331
EG A+ V P +V+W++N P+++ R + RG+ +L+I V ED G Y
Sbjct: 46 EGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVIHAVHEEDRGKY 104
Query: 332 SCVADNSLGRARRHVEVS 349
+C A N G + VE++
Sbjct: 105 TCEATNGSGARQVTVELT 122
Score = 41.1 bits (92), Expect = 0.009
Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 274 EGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSA-RGSNHTLLIADVQPEDFGNYS 332
EG A C + P EV W+++ + S + N +L+I+DV +D Y+
Sbjct: 1753 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1812
Query: 333 CVADNSLGRA 342
C A NSLG A
Sbjct: 1813 CKAVNSLGEA 1822
Score = 40.3 bits (90), Expect = 0.015
Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 13/114 (11%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASP----ETRHVTARRGGAAVLECRAAGN 201
+D G Y C+ + + V + P P + R VTA G + ++ C AG+
Sbjct: 619 EDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGD 678
Query: 202 PVPTVTWHRLNDSSSR-LGEGPQLQ--------LSRLERHHGGVYACTVDNGVG 246
P PTV W R + + G LQ L +++ H G Y + N VG
Sbjct: 679 PFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 732
Score = 37.1 bits (82), Expect = 0.14
Identities = 48/195 (24%), Positives = 70/195 (35%), Gaps = 19/195 (9%)
Query: 189 GGAAVLECRAAGNPVPTVTW-HRLNDSSS-------RLGEGPQLQLSRLERHHGGVYACT 240
G + + +GNP P V W H N+ + G L + + G Y C
Sbjct: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
Query: 241 VDNGVGPPVVTEFQLQVLYPPE------ITVERSWVHTGEGFRAELVCTVLADPPAEVSW 294
N G V T+ L V P + I+ RS V G + C + DP V W
Sbjct: 628 AWNSAGE-VRTQAVLTVQEPHDGTQPWFISKPRS-VTASLGQSVLISCAIAGDPFPTVHW 685
Query: 295 YQNSFPLSASE-RVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPG 353
++ L + TL++ VQP G Y + N +G V + +
Sbjct: 686 LRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNS 745
Query: 354 PARFTSPPLARAPHS 368
AR + P R P S
Sbjct: 746 SAR--ALPRGREPAS 758
Score = 35.1 bits (77), Expect = 0.58
Identities = 30/113 (26%), Positives = 44/113 (38%), Gaps = 11/113 (9%)
Query: 148 AGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVT 207
A ++ + S V +V ++ + P+ P R++ + G A E R G P P VT
Sbjct: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPP--RNLCIKEGATAKFEGRVRGYPEPQVT 65
Query: 208 WHRLNDSSSRLG--------EGP-QLQLSRLERHHGGVYACTVDNGVGPPVVT 251
WHR + G G L + + G Y C NG G VT
Sbjct: 66 WHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVT 118
Score = 34.7 bits (76), Expect = 0.76
Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 9/106 (8%)
Query: 184 VTARRGGAAVLECRAAGNPVPTVTWHRLN---DSSSRLG----EGPQ-LQLSRLERHHGG 235
V + G C+ G P P VTW + N S+R+ G Q L++ + + G
Sbjct: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
Query: 236 VYACTVDNGVGPPVVT-EFQLQVLYPPEITVERSWVHTGEGFRAEL 280
VY C V NG G ++ E +Q L + R T R E+
Sbjct: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEV 275
>AL109804-4|CAC17543.1| 1709|Homo sapiens sialic acid binding Ig-like
lectin 1, sialoadhesin protein.
Length = 1709
Score = 64.5 bits (150), Expect = 8e-10
Identities = 63/217 (29%), Positives = 87/217 (40%), Gaps = 20/217 (9%)
Query: 142 RMIFQD--AGD--YVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECR 197
R+ QD AGD YVC + + + T+ L R E + G A L CR
Sbjct: 1410 RLQVQDVPAGDDTYVCTAQNLLG--SISTIGRLQVEGARVVAEPG-LDVPEGAALNLSCR 1466
Query: 198 AAGNPVP----TVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
G P P T W ND P L + + R G+Y C + G
Sbjct: 1467 LLGGPGPVGNSTFAWF-WNDRRLHAEPVPTLAFTHVARAQAGMYHCLAELPTGAAASAPV 1525
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
L+VLYPP+ +V G R L C V ++P A ++ + S +++S+ A
Sbjct: 1526 MLRVLYPPKTPTMMVFVEPEGGLRGILDCRVDSEPLASLTLHLGSRLVASSQPQGAPAEP 1585
Query: 314 SNHTL-----LIADVQ---PEDFGNYSCVADNSLGRA 342
H L L D++ P D G Y C A N LG A
Sbjct: 1586 HIHVLASPNALRVDIEALRPSDQGEYICSASNVLGSA 1622
Score = 62.1 bits (144), Expect = 4e-09
Identities = 64/208 (30%), Positives = 85/208 (40%), Gaps = 22/208 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNPV 203
+D G Y C S R Q +T L VR +PE G + C
Sbjct: 1234 RDEGFYSC--SARSPLGQANTSLELRLEGVRVILAPEA---AVPEGAPITVTCADPAAHA 1288
Query: 204 PTV-TWHRLNDSSSRLGEGPQLQLSRL--ERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
PT+ TW+ + L EGP LS L R H G Y+C + G LQVLY
Sbjct: 1289 PTLYTWYH---NGRWLQEGPAASLSFLVATRAHAGAYSCQAQDAQGTRSSRPAALQVLYA 1345
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT--- 317
P+ V S+ + A + CTV ++PPAE++ + L+ S V A G+ H
Sbjct: 1346 PQDAVLSSFRDSRARSMAVIQCTVDSEPPAELALSHDGKVLATSSGVHSLASGTGHVQVA 1405
Query: 318 -----LLIADVQPEDFGNYSCVADNSLG 340
L + DV P Y C A N LG
Sbjct: 1406 RNALRLQVQDV-PAGDDTYVCTAQNLLG 1432
Score = 53.2 bits (122), Expect = 2e-06
Identities = 59/249 (23%), Positives = 99/249 (39%), Gaps = 17/249 (6%)
Query: 144 IFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECR----AA 199
+ ++ G Y+C+ S+ + + +P H T + G A L C AA
Sbjct: 680 LLEEEGLYLCEASNALGNASTSATFNGQATVLAIAPS--H-TLQEGTEANLTCNVSREAA 736
Query: 200 GNPVPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
G+P +W R N G + L + R +YAC + G + T L VLY
Sbjct: 737 GSPA-NFSWFR-NGVLWAQGPLETVTLLPVARTDAALYACRILTEAGAQLSTPVLLSVLY 794
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS--------ERVTMSA 311
PP+ + + G+G A +CTV + P A ++ + L+ S R A
Sbjct: 795 PPDRPKLSALLDMGQGHMALFICTVDSRPLALLALFHGEHLLATSLGPQVPSHGRFQAKA 854
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTL 371
++ L + ++ D G+Y C A N LG + + R + + P + + L
Sbjct: 855 EANSLKLEVRELGLGDSGSYRCEATNVLGSSNTSLFFQVRGAWVQVSPSPELQEGQAVVL 914
Query: 372 SFAVDSYPP 380
S V + P
Sbjct: 915 SCQVHTGVP 923
Score = 51.2 bits (117), Expect = 8e-06
Identities = 54/208 (25%), Positives = 88/208 (42%), Gaps = 12/208 (5%)
Query: 144 IFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRA-AGNP 202
+ +D G Y+C+ S+ + + +V+ P T R G L C +P
Sbjct: 1058 MLEDEGVYICEASNTLGQASASADFDAQAVNVQVWPGA---TVREGQLVNLTCLVWTTHP 1114
Query: 203 VP-TVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDN-GVGPPVVTEFQLQVLYP 260
T TW++ D RL + + L + Y C V G P + L VLY
Sbjct: 1115 AQLTYTWYQ--DGQQRL-DAHSIPLPNVTVRDATSYRCGVGPPGRAPRLSRPITLDVLYA 1171
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P + + G A ++CTV + PPA+++ L++S T ++ + L +
Sbjct: 1172 PRNLRLTYLLESHGGQLALVLCTVDSRPPAQLALSHAGRLLASS---TAASVPNTLRLEL 1228
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEV 348
QP D G YSC A + LG+A +E+
Sbjct: 1229 RGPQPRDEGFYSCSARSPLGQANTSLEL 1256
Score = 46.4 bits (105), Expect = 2e-04
Identities = 53/211 (25%), Positives = 80/211 (37%), Gaps = 19/211 (9%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+G Y C+ ++ + + V+ SP + G A VL C+ VP
Sbjct: 870 DSGSYRCEATNVLGSSNTSLFFQVRGAWVQVSPSPE---LQEGQAVVLSCQVHTG-VPEG 925
Query: 207 TWHRLNDSSSRLGEGPQ--LQLSRLERHHGGVYACTVD--NGVGPPVVTEFQLQVLYPPE 262
T +R L E L+ + + G Y C + L V Y P
Sbjct: 926 TSYRWYRDGQPLQESTSATLRFAAITLTQAGAYHCQAQAPGSATTSLAAPISLHVSYAPR 985
Query: 263 ITVERSWVHTGEGFRAELVCTVLADPPAEV----------SWYQN-SFPLSASERVTMSA 311
+ + TG G L+C V +DPPA++ S Q P +S R+ ++
Sbjct: 986 HVTLTTLMDTGPGRLGLLLCRVDSDPPAQLRLLHGDRLVASTLQGVGGPEGSSPRLHVAV 1045
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+ L I ED G Y C A N+LG+A
Sbjct: 1046 APNTLRLEIHGAMLEDEGVYICEASNTLGQA 1076
Score = 46.0 bits (104), Expect = 3e-04
Identities = 55/210 (26%), Positives = 84/210 (40%), Gaps = 24/210 (11%)
Query: 143 MIFQDAGDYV-CQIS--DRVARDQVHTVEVLVPPSVRA--SPETRHVTARRGGAAVLECR 197
M +QD G + CQ+S + A+ ++H P V+ SP R++ G L C+
Sbjct: 206 MSWQDHGRILRCQLSVANHRAQSEIHLQVKYAPKGVKILLSPSGRNILP--GELVTLTCQ 263
Query: 198 AAGN--PVPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQL 255
+ V ++ W L D + L L + GVY C +NGVG V L
Sbjct: 264 VNSSYPAVSSIKW--LKDGVRLQTKTGVLHLPQAAWSDAGVYTCQAENGVGSLVSPPISL 321
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEV--SWYQNSFPLSASERVTMSARG 313
+ + E+ V + E LVC + P+++ SWY+N L +
Sbjct: 322 HI-FMAEVQVSPAGPIL-ENQTVTLVCNTPNEAPSDLRYSWYKNHVLLEDAH-------- 371
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRAR 343
+HTL + D G Y C N G R
Sbjct: 372 -SHTLRLHLATRADTGFYFCEVQNVHGSER 400
Score = 44.8 bits (101), Expect = 7e-04
Identities = 52/209 (24%), Positives = 84/209 (40%), Gaps = 16/209 (7%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEV-LVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
+ DAG Y CQ + V + + + V+ SP + + L C N
Sbjct: 297 WSDAGVYTCQAENGVGSLVSPPISLHIFMAEVQVSPAGPILENQ---TVTLVCNTP-NEA 352
Query: 204 PT---VTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
P+ +W++ N L+L R G Y C V N G + V +P
Sbjct: 353 PSDLRYSWYK-NHVLLEDAHSHTLRLHLATRADTGFYFCEVQNVHGSERSGPVSVVVNHP 411
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA-------SERVTMSARG 313
P V +++ T G L C+V+++P A + L++ S R + ++
Sbjct: 412 PLTPVLTAFLETQAGLVGILHCSVVSEPLATLVLSHGGHILASTSGDSDHSPRFSGTSGP 471
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRA 342
++ L I D++ D G Y C A NSLG A
Sbjct: 472 NSLRLEIRDLEETDSGEYKCSATNSLGNA 500
Score = 44.0 bits (99), Expect = 0.001
Identities = 59/230 (25%), Positives = 91/230 (39%), Gaps = 32/230 (13%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPS-VRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D+G+Y C ++ + + T++ + + SP V G A L CR+ +P P
Sbjct: 485 DSGEYKCSATNSLG-NATSTLDFHANAARLLISPAAEVV---EGQAVTLSCRSGLSPTPD 540
Query: 206 V--TWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNG---VGPPVVTEFQLQVLYP 260
+W+ LN + G G L L G Y C +G GP + L VLYP
Sbjct: 541 ARFSWY-LNGALLHEGPGSSLLLPAASSTDAGSYHCRARDGHSASGPS--SPAVLTVLYP 597
Query: 261 PE-----ITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ------NSFPL-------- 301
P ++ G G R L+C V +DPPA + S P
Sbjct: 598 PRQPTFTTRLDLDAAGAGAGRRGLLLCRVDSDPPARLQLLHKDRVVATSLPSGGGCSTCG 657
Query: 302 SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR 351
S R+ ++ + + I + E+ G Y C A N+LG A +G+
Sbjct: 658 GCSPRMKVTKAPNLLRVEIHNPLLEEEGLYLCEASNALGNASTSATFNGQ 707
>AL109804-3|CAC17542.1| 462|Homo sapiens sialic acid binding
Ig-like lectin 1, sialoadhesin protein.
Length = 462
Score = 64.5 bits (150), Expect = 8e-10
Identities = 63/217 (29%), Positives = 87/217 (40%), Gaps = 20/217 (9%)
Query: 142 RMIFQD--AGD--YVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECR 197
R+ QD AGD YVC + + + T+ L R E + G A L CR
Sbjct: 223 RLQVQDVPAGDDTYVCTAQNLLG--SISTIGRLQVEGARVVAEPG-LDVPEGAALNLSCR 279
Query: 198 AAGNPVP----TVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
G P P T W ND P L + + R G+Y C + G
Sbjct: 280 LLGGPGPVGNSTFAWF-WNDRRLHAEPVPTLAFTHVARAQAGMYHCLAELPTGAAASAPV 338
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
L+VLYPP+ +V G R L C V ++P A ++ + S +++S+ A
Sbjct: 339 MLRVLYPPKTPTMMVFVEPEGGLRGILDCRVDSEPLASLTLHLGSRLVASSQPQGAPAEP 398
Query: 314 SNHTL-----LIADVQ---PEDFGNYSCVADNSLGRA 342
H L L D++ P D G Y C A N LG A
Sbjct: 399 HIHVLASPNALRVDIEALRPSDQGEYICSASNVLGSA 435
Score = 62.1 bits (144), Expect = 4e-09
Identities = 64/208 (30%), Positives = 85/208 (40%), Gaps = 22/208 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNPV 203
+D G Y C S R Q +T L VR +PE G + C
Sbjct: 47 RDEGFYSC--SARSPLGQANTSLELRLEGVRVILAPEA---AVPEGAPITVTCADPAAHA 101
Query: 204 PTV-TWHRLNDSSSRLGEGPQLQLSRL--ERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
PT+ TW+ + L EGP LS L R H G Y+C + G LQVLY
Sbjct: 102 PTLYTWYH---NGRWLQEGPAASLSFLVATRAHAGAYSCQAQDAQGTRSSRPAALQVLYA 158
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT--- 317
P+ V S+ + A + CTV ++PPAE++ + L+ S V A G+ H
Sbjct: 159 PQDAVLSSFRDSRARSMAVIQCTVDSEPPAELALSHDGKVLATSSGVHSLASGTGHVQVA 218
Query: 318 -----LLIADVQPEDFGNYSCVADNSLG 340
L + DV P Y C A N LG
Sbjct: 219 RNALRLQVQDV-PAGDDTYVCTAQNLLG 245
Score = 34.7 bits (76), Expect = 0.76
Identities = 23/71 (32%), Positives = 39/71 (54%), Gaps = 3/71 (4%)
Query: 278 AELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADN 337
A ++CTV + PPA+++ L++S T ++ + L + QP D G YSC A +
Sbjct: 2 ALVLCTVDSRPPAQLALSHAGRLLASS---TAASVPNTLRLELRGPQPRDEGFYSCSARS 58
Query: 338 SLGRARRHVEV 348
LG+A +E+
Sbjct: 59 PLGQANTSLEL 69
>AK024462-1|BAB15752.1| 977|Homo sapiens FLJ00055 protein protein.
Length = 977
Score = 64.5 bits (150), Expect = 8e-10
Identities = 63/217 (29%), Positives = 87/217 (40%), Gaps = 20/217 (9%)
Query: 142 RMIFQD--AGD--YVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECR 197
R+ QD AGD YVC + + + T+ L R E + G A L CR
Sbjct: 678 RLQVQDVPAGDDTYVCTAQNLLG--SISTIGRLQVEGARVVAEPG-LDVPEGAALNLSCR 734
Query: 198 AAGNPVP----TVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
G P P T W ND P L + + R G+Y C + G
Sbjct: 735 LLGGPGPVGNSTFAWF-WNDRRLHAEPVPTLAFTHVARAQAGMYHCLAELPTGAAASAPV 793
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
L+VLYPP+ +V G R L C V ++P A ++ + S +++S+ A
Sbjct: 794 MLRVLYPPKTPTMMVFVEPEGGLRGILDCRVDSEPLASLTLHLGSRLVASSQPQGAPAEP 853
Query: 314 SNHTL-----LIADVQ---PEDFGNYSCVADNSLGRA 342
H L L D++ P D G Y C A N LG A
Sbjct: 854 HIHVLASPNALRVDIEALRPSDQGEYICSASNVLGSA 890
Score = 62.1 bits (144), Expect = 4e-09
Identities = 64/208 (30%), Positives = 85/208 (40%), Gaps = 22/208 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNPV 203
+D G Y C S R Q +T L VR +PE G + C
Sbjct: 502 RDEGFYSC--SARSPLGQANTSLELRLEGVRVILAPEA---AVPEGAPITVTCADPAAHA 556
Query: 204 PTV-TWHRLNDSSSRLGEGPQLQLSRL--ERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
PT+ TW+ + L EGP LS L R H G Y+C + G LQVLY
Sbjct: 557 PTLYTWYH---NGRWLQEGPAASLSFLVATRAHAGAYSCQAQDAQGTRSSRPAALQVLYA 613
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT--- 317
P+ V S+ + A + CTV ++PPAE++ + L+ S V A G+ H
Sbjct: 614 PQDAVLSSFRDSRARSMAVIQCTVDSEPPAELALSHDGKVLATSSGVHSLASGTGHVQVA 673
Query: 318 -----LLIADVQPEDFGNYSCVADNSLG 340
L + DV P Y C A N LG
Sbjct: 674 RNALRLQVQDV-PAGDDTYVCTAQNLLG 700
Score = 51.2 bits (117), Expect = 8e-06
Identities = 54/208 (25%), Positives = 88/208 (42%), Gaps = 12/208 (5%)
Query: 144 IFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRA-AGNP 202
+ +D G Y+C+ S+ + + +V+ P T R G L C +P
Sbjct: 326 MLEDEGVYICEASNTLGQASASADFDAQAVNVQVWPGA---TVREGQLVNLTCLVWTTHP 382
Query: 203 VP-TVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDN-GVGPPVVTEFQLQVLYP 260
T TW++ D RL + + L + Y C V G P + L VLY
Sbjct: 383 AQLTYTWYQ--DGQQRL-DAHSIPLPNVTVRDATSYRCGVGPPGRAPRLSRPITLDVLYA 439
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P + + G A ++CTV + PPA+++ L++S T ++ + L +
Sbjct: 440 PRNLRLTYLLESHGGQLALVLCTVDSRPPAQLALSHAGRLLASS---TAASVPNTLRLEL 496
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEV 348
QP D G YSC A + LG+A +E+
Sbjct: 497 RGPQPRDEGFYSCSARSPLGQANTSLEL 524
Score = 50.8 bits (116), Expect = 1e-05
Identities = 48/191 (25%), Positives = 78/191 (40%), Gaps = 10/191 (5%)
Query: 198 AAGNPVPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQV 257
AAG+P +W R N G + L + R +YAC + G + T L V
Sbjct: 3 AAGSPA-NFSWFR-NGVLWAQGPLETVTLLPVARTDAALYACRILTEAGAQLSTPVLLSV 60
Query: 258 LYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS--------ERVTM 309
LYPP+ + + G+G A +CTV + P A ++ + L+ S R
Sbjct: 61 LYPPDRPKLSALLDMGQGHMALFICTVDSRPLALLALFHGEHLLATSLGPQVPSHGRFQA 120
Query: 310 SARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSY 369
A ++ L + ++ D G+Y C A N LG + + R + + P + +
Sbjct: 121 KAEANSLKLEVRELGLGDSGSYRCEATNVLGSSNTSLFFQVRGAWVQVSPSPELQEGQAV 180
Query: 370 TLSFAVDSYPP 380
LS V + P
Sbjct: 181 VLSCQVHTGVP 191
Score = 46.4 bits (105), Expect = 2e-04
Identities = 53/211 (25%), Positives = 80/211 (37%), Gaps = 19/211 (9%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+G Y C+ ++ + + V+ SP + G A VL C+ VP
Sbjct: 138 DSGSYRCEATNVLGSSNTSLFFQVRGAWVQVSPSPE---LQEGQAVVLSCQVHTG-VPEG 193
Query: 207 TWHRLNDSSSRLGEGPQ--LQLSRLERHHGGVYACTVD--NGVGPPVVTEFQLQVLYPPE 262
T +R L E L+ + + G Y C + L V Y P
Sbjct: 194 TSYRWYRDGQPLQESTSATLRFAAITLTQAGAYHCQAQAPGSATTSLAAPISLHVSYAPR 253
Query: 263 ITVERSWVHTGEGFRAELVCTVLADPPAEV----------SWYQN-SFPLSASERVTMSA 311
+ + TG G L+C V +DPPA++ S Q P +S R+ ++
Sbjct: 254 HVTLTTLMDTGPGRLGLLLCRVDSDPPAQLRLLHGDRLVASTLQGVGGPEGSSPRLHVAV 313
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+ L I ED G Y C A N+LG+A
Sbjct: 314 APNTLRLEIHGAMLEDEGVYICEASNTLGQA 344
>AF363368-1|AAM60750.1| 388|Homo sapiens TSLC1-like 2 protein.
Length = 388
Score = 64.5 bits (150), Expect = 8e-10
Identities = 64/224 (28%), Positives = 88/224 (39%), Gaps = 24/224 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRA-AGNPVP 204
+D G Y CQ+ Q+ T+ VLV P E R A GG L C P
Sbjct: 97 EDEGGYFCQLYTEDTHHQIATLTVLVAPE-NPVVEVRE-QAVEGGEVELSCLVPRSRPAA 154
Query: 205 TVTWHR----LNDSSSRLGEGPQLQLS-----RLER-HHGGVYACTVDNGV---GPPVVT 251
T+ W+R L SS G ++ R++R GG+ C N G T
Sbjct: 155 TLRWYRDRKELKGVSSSQENGKVWSVASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQT 214
Query: 252 EFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADP-PAEVSWYQNSFPLSASERVTMS 310
++ L V Y P + S EG L C V +P P ++ W + +E +
Sbjct: 215 QYVLDVQYSPTARIHASQAVVREGDTLVLTCAVTGNPRPNQIRWNR------GNESLPER 268
Query: 311 ARGSNHTLLIADVQPEDFGNYSCVADNSLGRARR-HVEVSGRPG 353
A TL + + D G Y+C A N G AR +V V PG
Sbjct: 269 AEAVGETLTLPGLVSADNGTYTCEASNKHGHARALYVLVVYDPG 312
>AF230073-1|AAK00757.1| 1709|Homo sapiens sialoadhesin protein.
Length = 1709
Score = 64.5 bits (150), Expect = 8e-10
Identities = 63/217 (29%), Positives = 87/217 (40%), Gaps = 20/217 (9%)
Query: 142 RMIFQD--AGD--YVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECR 197
R+ QD AGD YVC + + + T+ L R E + G A L CR
Sbjct: 1410 RLQVQDVPAGDDTYVCTAQNLLG--SISTIGRLQVEGARVVAEPG-LDVPEGAALNLSCR 1466
Query: 198 AAGNPVP----TVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEF 253
G P P T W ND P L + + R G+Y C + G
Sbjct: 1467 LLGGPGPVGNSTFAWF-WNDRRLHAEPVPTLAFTHVARAQAGMYHCLAELPTGAAASAPV 1525
Query: 254 QLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARG 313
L+VLYPP+ +V G R L C V ++P A ++ + S +++S+ A
Sbjct: 1526 MLRVLYPPKTPTMMVFVEPEGGLRGILDCRVDSEPLASLTLHLGSRLVASSQPQGAPAEP 1585
Query: 314 SNHTL-----LIADVQ---PEDFGNYSCVADNSLGRA 342
H L L D++ P D G Y C A N LG A
Sbjct: 1586 HIHVLASPNALRVDIEALRPSDQGEYICSASNVLGSA 1622
Score = 64.1 bits (149), Expect = 1e-09
Identities = 65/208 (31%), Positives = 86/208 (41%), Gaps = 22/208 (10%)
Query: 146 QDAGDYVCQISDRVARDQVHTVEVLVPPSVRA--SPETRHVTARRGGAAVLECRAAGNPV 203
+D G Y C S R Q +T L VR +PE G + C
Sbjct: 1234 RDEGFYSC--SARSPLGQANTSLELRLEGVRVILAPEA---AVPEGAPITVTCADPAAHA 1288
Query: 204 PTV-TWHRLNDSSSRLGEGPQLQLSRL--ERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
PT+ TW+ + L EGP LS L R H G Y+C + G LQVLY
Sbjct: 1289 PTLYTWYH---NGRWLQEGPAASLSFLVATRAHAGAYSCQAQDAQGTRSSRPAALQVLYA 1345
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHT--- 317
P+ TV S+ + A + CTV ++PPAE++ + L+ S V A G+ H
Sbjct: 1346 PQDTVLSSFRDSRARSMAVIQCTVDSEPPAELALSHDGKVLATSSGVHSLASGTGHVQVA 1405
Query: 318 -----LLIADVQPEDFGNYSCVADNSLG 340
L + DV P Y C A N LG
Sbjct: 1406 RNALRLQVQDV-PAGDDTYVCTAQNLLG 1432
Score = 53.2 bits (122), Expect = 2e-06
Identities = 59/249 (23%), Positives = 99/249 (39%), Gaps = 17/249 (6%)
Query: 144 IFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECR----AA 199
+ ++ G Y+C+ S+ + + +P H T + G A L C AA
Sbjct: 680 LLEEEGLYLCEASNALGNASTSATFNGQATVLAIAPS--H-TLQEGTEANLTCNVSREAA 736
Query: 200 GNPVPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLY 259
G+P +W R N G + L + R +YAC + G + T L VLY
Sbjct: 737 GSPA-NFSWFR-NGVLWAQGPLETVTLLPVARTDAALYACRILTEAGAQLSTPVLLSVLY 794
Query: 260 PPEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSAS--------ERVTMSA 311
PP+ + + G+G A +CTV + P A ++ + L+ S R A
Sbjct: 795 PPDRPKLSALLDMGQGHMALFICTVDSRPLALLALFHGEHLLATSLGPQVPSHGRFQAKA 854
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGPARFTSPPLARAPHSYTL 371
++ L + ++ D G+Y C A N LG + + R + + P + + L
Sbjct: 855 EANSLKLEVRELGLGDSGSYRCEATNVLGSSNTSLFFQVRGAWVQVSPSPELQEGQAVVL 914
Query: 372 SFAVDSYPP 380
S V + P
Sbjct: 915 SCQVHTGVP 923
Score = 51.2 bits (117), Expect = 8e-06
Identities = 54/208 (25%), Positives = 88/208 (42%), Gaps = 12/208 (5%)
Query: 144 IFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRA-AGNP 202
+ +D G Y+C+ S+ + + +V+ P T R G L C +P
Sbjct: 1058 MLEDEGVYICEASNTLGQASASADFDAQAVNVQVWPGA---TVREGQLVNLTCLVWTTHP 1114
Query: 203 VP-TVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDN-GVGPPVVTEFQLQVLYP 260
T TW++ D RL + + L + Y C V G P + L VLY
Sbjct: 1115 AQLTYTWYQ--DGQQRL-DAHSIPLPNVTVRDATSYRCGVGPPGRAPRLSRPITLDVLYA 1171
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLI 320
P + + G A ++CTV + PPA+++ L++S T ++ + L +
Sbjct: 1172 PRNLRLTYLLESHGGQLALVLCTVDSRPPAQLALSHAGRLLASS---TAASVPNTLRLEL 1228
Query: 321 ADVQPEDFGNYSCVADNSLGRARRHVEV 348
QP D G YSC A + LG+A +E+
Sbjct: 1229 RGPQPRDEGFYSCSARSPLGQANTSLEL 1256
Score = 46.4 bits (105), Expect = 2e-04
Identities = 53/211 (25%), Positives = 80/211 (37%), Gaps = 19/211 (9%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTV 206
D+G Y C+ ++ + + V+ SP + G A VL C+ VP
Sbjct: 870 DSGSYRCEATNVLGSSNTSLFFQVRGAWVQVSPSPE---LQEGQAVVLSCQVHTG-VPEG 925
Query: 207 TWHRLNDSSSRLGEGPQ--LQLSRLERHHGGVYACTVD--NGVGPPVVTEFQLQVLYPPE 262
T +R L E L+ + + G Y C + L V Y P
Sbjct: 926 TSYRWYRDGQPLQESTSATLRFAAITLTQAGAYHCQAQAPGSATTSLAAPISLHVSYAPR 985
Query: 263 ITVERSWVHTGEGFRAELVCTVLADPPAEV----------SWYQN-SFPLSASERVTMSA 311
+ + TG G L+C V +DPPA++ S Q P +S R+ ++
Sbjct: 986 HVTLTTLMDTGPGRLGLLLCRVDSDPPAQLRLLHGDRLVASTLQGVGGPEGSSPRLHVAV 1045
Query: 312 RGSNHTLLIADVQPEDFGNYSCVADNSLGRA 342
+ L I ED G Y C A N+LG+A
Sbjct: 1046 APNTLRLEIHGAMLEDEGVYICEASNTLGQA 1076
Score = 46.0 bits (104), Expect = 3e-04
Identities = 55/210 (26%), Positives = 84/210 (40%), Gaps = 24/210 (11%)
Query: 143 MIFQDAGDYV-CQIS--DRVARDQVHTVEVLVPPSVRA--SPETRHVTARRGGAAVLECR 197
M +QD G + CQ+S + A+ ++H P V+ SP R++ G L C+
Sbjct: 206 MSWQDHGRILRCQLSVANHRAQSEIHLQVKYAPKGVKILLSPSGRNILP--GELVTLTCQ 263
Query: 198 AAGN--PVPTVTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQL 255
+ V ++ W L D + L L + GVY C +NGVG V L
Sbjct: 264 VNSSYPAVSSIKW--LKDGVRLQTKTGVLHLPQAAWSDAGVYTCQAENGVGSLVSPPISL 321
Query: 256 QVLYPPEITVERSWVHTGEGFRAELVCTVLADPPAEV--SWYQNSFPLSASERVTMSARG 313
+ + E+ V + E LVC + P+++ SWY+N L +
Sbjct: 322 HI-FMAEVQVSPAGPIL-ENQTVTLVCNTPNEAPSDLRYSWYKNHVLLEDAH-------- 371
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRAR 343
+HTL + D G Y C N G R
Sbjct: 372 -SHTLRLHLATRADTGFYFCEVQNVHGSER 400
Score = 44.8 bits (101), Expect = 7e-04
Identities = 52/209 (24%), Positives = 84/209 (40%), Gaps = 16/209 (7%)
Query: 145 FQDAGDYVCQISDRVARDQVHTVEV-LVPPSVRASPETRHVTARRGGAAVLECRAAGNPV 203
+ DAG Y CQ + V + + + V+ SP + + L C N
Sbjct: 297 WSDAGVYTCQAENGVGSLVSPPISLHIFMAEVQVSPAGPILENQ---TVTLVCNTP-NEA 352
Query: 204 PT---VTWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYP 260
P+ +W++ N L+L R G Y C V N G + V +P
Sbjct: 353 PSDLRYSWYK-NHVLLEDAHSHTLRLHLATRADTGFYFCEVQNVHGSERSGPVSVVVNHP 411
Query: 261 PEITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQNSFPLSA-------SERVTMSARG 313
P V +++ T G L C+V+++P A + L++ S R + ++
Sbjct: 412 PLTPVLTAFLETQAGLVGILHCSVVSEPLATLVLSHGGHILASTSGDSDHSPRFSGTSGP 471
Query: 314 SNHTLLIADVQPEDFGNYSCVADNSLGRA 342
++ L I D++ D G Y C A NSLG A
Sbjct: 472 NSLRLEIRDLEETDSGEYKCSATNSLGNA 500
Score = 44.0 bits (99), Expect = 0.001
Identities = 59/230 (25%), Positives = 91/230 (39%), Gaps = 32/230 (13%)
Query: 147 DAGDYVCQISDRVARDQVHTVEVLVPPS-VRASPETRHVTARRGGAAVLECRAAGNPVPT 205
D+G+Y C ++ + + T++ + + SP V G A L CR+ +P P
Sbjct: 485 DSGEYKCSATNSLG-NATSTLDFHANAARLLISPAAEVV---EGQAVTLSCRSGLSPTPD 540
Query: 206 V--TWHRLNDSSSRLGEGPQLQLSRLERHHGGVYACTVDNG---VGPPVVTEFQLQVLYP 260
+W+ LN + G G L L G Y C +G GP + L VLYP
Sbjct: 541 ARFSWY-LNGALLHEGPGSSLLLPAASSTDAGSYHCRARDGHSASGPS--SPAVLTVLYP 597
Query: 261 PE-----ITVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ------NSFPL-------- 301
P ++ G G R L+C V +DPPA + S P
Sbjct: 598 PRQPTFTTRLDLDAAGAGAGRRGLLLCRVDSDPPARLQLLHKDRVVATSLPSGGGCSTCG 657
Query: 302 SASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGR 351
S R+ ++ + + I + E+ G Y C A N+LG A +G+
Sbjct: 658 GCSPRMKVTKAPNLLRVEIHNPLLEEEGLYLCEASNALGNASTSATFNGQ 707
>Z29373-1|CAA82564.1| 1257|Homo sapiens neural cell adhesion
molecule L1 protein.
Length = 1257
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 184 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 243
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 244 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 303
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 304 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 362
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 363 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 411
Score = 48.0 bits (109), Expect = 8e-05
Identities = 62/238 (26%), Positives = 93/238 (39%), Gaps = 26/238 (10%)
Query: 138 NTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPET-RHVTARRGGAAVLEC 196
N+NF FQ G Y C S+++ H + ++ + + ET + V G + VL C
Sbjct: 101 NSNFAQRFQ--GIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPC 158
Query: 197 RAAGNPVPT-VTW------HRLNDSSSRLGEGPQLQLSR-LERHHGGVYACTVD-NGVGP 247
+ P + W H D +G+ L + L + Y C G
Sbjct: 159 NPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRT 218
Query: 248 PVVTE-FQLQVLYP-------PEI---TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ 296
+ E L+V P + T S + +G L C P + W +
Sbjct: 219 IIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLR 278
Query: 297 NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
S P+ A +RVT + N TL + V ED G Y C+A+NSLG AR V+ P
Sbjct: 279 PSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAP 333
Score = 47.6 bits (108), Expect = 1e-04
Identities = 74/302 (24%), Positives = 117/302 (38%), Gaps = 33/302 (10%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 419 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 478
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 479 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 537
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 538 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 593
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 594 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 649
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 650 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 701
Query: 451 DI 452
+
Sbjct: 702 PV 703
>M77640-1|AAC14352.1| 1257|Homo sapiens L1 cell adhesion molecule
protein.
Length = 1257
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 184 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 243
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 244 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 303
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 304 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 362
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 363 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 411
Score = 48.0 bits (109), Expect = 8e-05
Identities = 62/238 (26%), Positives = 93/238 (39%), Gaps = 26/238 (10%)
Query: 138 NTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPET-RHVTARRGGAAVLEC 196
N+NF FQ G Y C S+++ H + ++ + + ET + V G + VL C
Sbjct: 101 NSNFAQRFQ--GIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPC 158
Query: 197 RAAGNPVPT-VTW------HRLNDSSSRLGEGPQLQLSR-LERHHGGVYACTVD-NGVGP 247
+ P + W H D +G+ L + L + Y C G
Sbjct: 159 NPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRT 218
Query: 248 PVVTE-FQLQVLYP-------PEI---TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ 296
+ E L+V P + T S + +G L C P + W +
Sbjct: 219 IIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLR 278
Query: 297 NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
S P+ A +RVT + N TL + V ED G Y C+A+NSLG AR V+ P
Sbjct: 279 PSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAP 333
Score = 47.6 bits (108), Expect = 1e-04
Identities = 74/302 (24%), Positives = 117/302 (38%), Gaps = 33/302 (10%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 419 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 478
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 479 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 537
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 538 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 593
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 594 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 649
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 650 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 701
Query: 451 DI 452
+
Sbjct: 702 PV 703
>M74387-1|AAA59476.1| 1253|Homo sapiens cell adhesion molecule L1
protein.
Length = 1253
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 184 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 243
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 244 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 303
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 304 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 362
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 363 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 411
Score = 48.0 bits (109), Expect = 8e-05
Identities = 62/238 (26%), Positives = 93/238 (39%), Gaps = 26/238 (10%)
Query: 138 NTNFRMIFQDAGDYVCQISDRVARDQVHTVEVLVPPSVRASPET-RHVTARRGGAAVLEC 196
N+NF FQ G Y C S+++ H + ++ + + ET + V G + VL C
Sbjct: 101 NSNFAQRFQ--GIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPC 158
Query: 197 RAAGNPVPT-VTW------HRLNDSSSRLGEGPQLQLSR-LERHHGGVYACTVD-NGVGP 247
+ P + W H D +G+ L + L + Y C G
Sbjct: 159 NPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRT 218
Query: 248 PVVTE-FQLQVLYP-------PEI---TVERSWVHTGEGFRAELVCTVLADPPAEVSWYQ 296
+ E L+V P + T S + +G L C P + W +
Sbjct: 219 IIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLR 278
Query: 297 NSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLGRARRHVEVSGRPGP 354
S P+ A +RVT + N TL + V ED G Y C+A+NSLG AR V+ P
Sbjct: 279 PSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAP 333
Score = 47.6 bits (108), Expect = 1e-04
Identities = 74/302 (24%), Positives = 117/302 (38%), Gaps = 33/302 (10%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 419 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 478
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 479 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 537
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 538 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 593
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 594 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 649
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 650 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 701
Query: 451 DI 452
+
Sbjct: 702 PV 703
>DQ173642-2|ABC25979.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173641-2|ABC25974.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173640-2|ABC25969.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173639-2|ABC25964.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173638-2|ABC25959.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173637-2|ABC25954.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173636-2|ABC25949.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173635-2|ABC25944.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173634-2|ABC25939.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173633-2|ABC25934.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173632-2|ABC25929.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173631-2|ABC25924.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173630-2|ABC25919.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173629-2|ABC25914.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173628-2|ABC25909.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173627-2|ABC25904.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173626-2|ABC25899.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173625-2|ABC25894.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173624-2|ABC25889.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173623-2|ABC25884.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173622-2|ABC25879.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173621-2|ABC25874.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173620-2|ABC25869.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173619-2|ABC25864.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173618-2|ABC25859.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173617-2|ABC25854.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173616-2|ABC25849.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173615-2|ABC25844.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173614-2|ABC25839.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173613-2|ABC25834.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173612-2|ABC25829.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173611-2|ABC25824.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173610-2|ABC25819.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173609-2|ABC25814.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173608-2|ABC25809.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173607-2|ABC25804.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173606-2|ABC25799.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173605-2|ABC25794.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173604-2|ABC25789.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173603-2|ABC25784.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173602-2|ABC25779.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173601-2|ABC25774.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173600-2|ABC25769.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173599-2|ABC25764.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
>DQ173598-2|ABC25759.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/230 (26%), Positives = 92/230 (40%), Gaps = 21/230 (9%)
Query: 130 RITSEQHGNTNFRMIF--QDAGDYVCQISDRVARD--QVHTVEVLV----------PPSV 175
R+T Q+GN F + + DY+C R Q +++ V P +
Sbjct: 16 RVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLL 75
Query: 176 RASPETRHVTARRGGAAVLECRAAGNPVPTVTWHRLN-----DSSSRLGEGPQLQLSRLE 230
+ + H+ A +G VLEC A G P PT+ W R + D + LQL ++
Sbjct: 76 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 135
Query: 231 RHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAELVCTVLADPPA 290
G Y C +N +G + P + +S ++ G G A L C V P
Sbjct: 136 EEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY-GPGETARLDCQVQGRPQP 194
Query: 291 EVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSLG 340
EV+W N P+ + R L++++VQP D C A N G
Sbjct: 195 EVTWRINGIPVEELAK-DQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 243
Score = 46.8 bits (106), Expect = 2e-04
Identities = 74/300 (24%), Positives = 116/300 (38%), Gaps = 33/300 (11%)
Query: 167 VEVLVPPSVRASPETRHVTARRGGAAVLECRAAGNPVPTVTW------HRLNDSSSRLGE 220
+ V+ P+ + + + A +G A L C+A G PVP+V W L D
Sbjct: 251 IYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA 310
Query: 221 GPQLQLSRLERHHGGVYACTVDNGVGPPVVTEFQLQVLYPPEITVERSWVHTGEGFRAEL 280
L + L+ + G Y C N V L+V +IT +G R
Sbjct: 311 NGTLGIRDLQANDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 369
Query: 281 VCTVLADPPAE--VSWY---QNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVA 335
C DP + ++W ++ L S++ + + L+I + D GNYSCVA
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFI----EDGRLVIHSLDYSDQGNYSCVA 425
Query: 336 DNSLG--RARRHVEVSGRPGPARFTSPPLARAP-HSYTLSFAVDSYPPLDELRLLYRQ-- 390
L +R + V G PGP P L + H T S S+ P ++ +
Sbjct: 426 STELDVVESRAQLLVVGSPGPV----PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYD 481
Query: 391 LAINESFQQPGRWHDVVLAAPAAKGSLTHRVSHELRGLQPAAVYEAIVQAKNRYGWNEVS 450
+ + P +W+ + P + S T ++S P Y V A N+YG E S
Sbjct: 482 IEFEDKEMAPEKWYSLG-KVPGNQTSTTLKLS-------PYVHYTFRVTAINKYGPGEPS 533
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 280 LVCTVLADPPAEVSWYQNSFPLSASERVTMSARGSNHTLLIADVQPEDFGNYSCVADNSL 339
L C P + W + S P+ A +RVT + N TL + V ED G Y C+A+NSL
Sbjct: 94 LECIAEGFPTPTIKWLRPSGPMPA-DRVTY--QNHNKTLQLLKVGEEDDGEYRCLAENSL 150
Query: 340 GRARRHVEVSGRPGP 354
G AR V+ P
Sbjct: 151 GSARHAYYVTVEAAP 165
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.134 0.412
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 78,982,637
Number of Sequences: 224733
Number of extensions: 3430370
Number of successful extensions: 25201
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 2433
Number of HSP's successfully gapped in prelim test: 941
Number of HSP's that attempted gapping in prelim test: 13816
Number of HSP's gapped (non-prelim): 8077
length of query: 500
length of database: 73,234,838
effective HSP length: 93
effective length of query: 407
effective length of database: 52,334,669
effective search space: 21300210283
effective search space used: 21300210283
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 67 (31.1 bits)
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