Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001699-TA|BGIBMGA001699-PA|IPR003590|Leucine-rich
repeat, ribonuclease inhibitor subtype, IPR009109|Ran-GTPase
activating protein 1, C-terminal, IPR001611|Leucine-rich repeat
(542 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X82260-1|CAA57714.1| 587|Homo sapiens RanGAP1 protein. 255 3e-67
CR456557-1|CAG30443.1| 587|Homo sapiens RANGAP1 protein. 255 3e-67
BC041396-1|AAH41396.1| 587|Homo sapiens RANGAP1 protein protein. 255 3e-67
BC014044-1|AAH14044.1| 587|Homo sapiens Ran GTPase activating p... 255 3e-67
AL035681-3|CAB63073.1| 587|Homo sapiens Ran GTPase activating p... 255 3e-67
AB058738-1|BAB47464.1| 623|Homo sapiens KIAA1835 protein protein. 255 3e-67
AY601811-1|AAT48367.1| 1065|Homo sapiens caterpiller 16.2 protein. 52 5e-06
AK074109-1|BAB84935.1| 499|Homo sapiens FLJ00180 protein protein. 52 5e-06
AF501291-1|AAM22459.1| 223|Homo sapiens CARD15-like protein pro... 49 4e-05
AJ303140-1|CAC42117.1| 1013|Homo sapiens LRR-containing protein ... 49 5e-05
AF178930-1|AAG33677.1| 1040|Homo sapiens NOD2 protein protein. 49 5e-05
AF501292-1|AAM22460.1| 195|Homo sapiens CARD15-like protein pro... 45 8e-04
BC040339-1|AAH40339.1| 953|Homo sapiens NOD1 protein protein. 44 0.002
AF149774-1|AAD43922.1| 953|Homo sapiens NOD1 protein protein. 44 0.002
AF126484-1|AAD29125.1| 953|Homo sapiens CARD4 protein. 44 0.002
AF113925-1|AAD28350.1| 953|Homo sapiens Nod1 protein. 44 0.002
AC006027-1|AAS46897.1| 953|Homo sapiens unknown protein. 44 0.002
AY051117-1|AAL12497.1| 1034|Homo sapiens cryopyrin protein. 43 0.003
AL606804-9|CAI17153.1| 1036|Homo sapiens cold autoinflammatory s... 43 0.003
AF468522-1|AAL78632.1| 1036|Homo sapiens NALP3 long isoform prot... 43 0.003
AF420469-1|AAL65136.1| 1034|Homo sapiens PYRIN-containing APAF1-... 43 0.003
AF410477-1|AAL33908.1| 1034|Homo sapiens cryopyrin protein. 43 0.003
AY154468-1|AAO18164.1| 1043|Homo sapiens NALP13 protein. 40 0.022
BC117211-1|AAI17212.1| 979|Homo sapiens NLRP3 protein protein. 39 0.039
AY422168-1|AAQ98889.1| 977|Homo sapiens cryopyrin deletion 4 is... 39 0.039
AL606804-11|CAI17155.1| 977|Homo sapiens cold autoinflammatory ... 39 0.039
X74301-1|CAA52354.1| 1130|Homo sapiens (MHC) class II transactiv... 38 0.068
U18259-1|AAA88861.1| 1130|Homo sapiens MHC class II transactivat... 38 0.068
AY699071-1|AAU06586.1| 1107|Homo sapiens CIITA IV protein. 38 0.068
AY084054-1|AAM15723.1| 546|Homo sapiens MHC class II transactiv... 38 0.068
AL160037-1|CAH72024.1| 1371|Homo sapiens leucine rich repeat con... 38 0.090
AL024509-3|CAI21665.1| 1371|Homo sapiens leucine rich repeat con... 38 0.090
AL022170-1|CAI21583.1| 1371|Homo sapiens leucine rich repeat con... 38 0.090
AK125696-1|BAC86250.1| 499|Homo sapiens protein ( Homo sapiens ... 38 0.090
EF064747-1|ABK41930.1| 1130|Homo sapiens class II, major histoco... 38 0.12
BC032841-1|AAH32841.1| 419|Homo sapiens leucine rich repeat con... 35 0.63
BC008782-1|AAH08782.1| 1219|Homo sapiens nuclear factor of kappa... 35 0.84
AB209126-1|BAD92363.1| 897|Homo sapiens I-kappa-B-related prote... 35 0.84
EF452236-1|ABO40479.1| 1866|Homo sapiens NOD4 protein. 34 1.1
BC063566-1|AAH63566.1| 837|Homo sapiens NLRC5 protein protein. 34 1.1
BC035022-1|AAH35022.1| 501|Homo sapiens hypothetical protein MG... 34 1.1
AL353588-2|CAI40746.1| 501|Homo sapiens protein ( Human DNA seq... 34 1.1
AF389420-1|AAO59377.1| 1866|Homo sapiens NOD27 protein. 34 1.1
AB113647-1|BAD26751.1| 1475|Homo sapiens RGD, leucine-rich repea... 33 1.9
AY154464-1|AAO18160.1| 986|Homo sapiens NALP9 protein. 33 2.6
AF165217-1|AAF01277.1| 345|Homo sapiens Sk-tropomodulin protein. 33 2.6
BC121160-1|AAI21161.1| 462|Homo sapiens chromosome 14 open read... 32 4.5
BC121159-1|AAI21160.1| 462|Homo sapiens chromosome 14 open read... 32 4.5
AK027416-1|BAB55098.1| 753|Homo sapiens protein ( Homo sapiens ... 32 4.5
AK027414-1|BAB55096.1| 753|Homo sapiens protein ( Homo sapiens ... 32 4.5
AF111169-4|AAD44364.1| 608|Homo sapiens unknown protein. 32 4.5
AB208891-1|BAD92128.1| 983|Homo sapiens Cryopyrin deletion 4 is... 32 4.5
BC020542-1|AAH20542.1| 352|Homo sapiens tropomodulin 3 (ubiquit... 32 5.9
BC017810-1|AAH17810.1| 345|Homo sapiens tropomodulin 4 (muscle)... 32 5.9
AL592424-9|CAI16383.1| 345|Homo sapiens tropomodulin 4 (muscle)... 32 5.9
AF393375-1|AAM73676.1| 345|Homo sapiens tropomodulin 4 protein. 32 5.9
AF321183-1|AAK06765.1| 345|Homo sapiens muscle tropomodulin pro... 32 5.9
AF237631-1|AAF45299.1| 352|Homo sapiens ubiquitous tropomodulin... 32 5.9
AF177173-1|AAF31672.1| 345|Homo sapiens tropomodulin 4 protein. 32 5.9
AF177171-1|AAF31670.1| 352|Homo sapiens tropomodulin 3 protein. 32 5.9
EF452237-1|ABO40480.1| 975|Homo sapiens NOD5 protein. 31 7.8
BC110890-1|AAI10891.1| 975|Homo sapiens NLRX1 protein protein. 31 7.8
AY245437-1|AAP31240.1| 975|Homo sapiens NOD26 protein. 31 7.8
AK090431-1|BAC03412.1| 778|Homo sapiens FLJ00348 protein protein. 31 7.8
AK025131-1|BAB15075.1| 554|Homo sapiens protein ( Homo sapiens ... 31 7.8
AB094095-1|BAC76049.1| 975|Homo sapiens DLNB26 protein. 31 7.8
>X82260-1|CAA57714.1| 587|Homo sapiens RanGAP1 protein.
Length = 587
Score = 255 bits (624), Expect = 3e-67
Identities = 138/290 (47%), Positives = 177/290 (61%), Gaps = 9/290 (3%)
Query: 1 MATFDLNSLNTVLDEPAQPETGVDFSGKSLKLDTAKDAQQIVDAINKCPNLQYLALTGNT 60
MA+ D+ L L + + F GKSLKL+TA+DA+ ++ I +L+ L L GNT
Sbjct: 1 MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT 60
Query: 61 LGVTAAHAISKALESHPELKIARFSDMFTGRMKTEIPPALSALGDGMIAAGARLAVLDLS 120
+GV AA I+KALE ELK +SDMFTGR++TEIPPAL +LG+G+I AGA+L LDLS
Sbjct: 61 VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS 120
Query: 121 DNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXXXXITGGXXXXXXXXXXXXXXX------ 174
DNAFGP GV+G LL+S C I GG
Sbjct: 121 DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL 180
Query: 175 ---VFIAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNH 231
VF+AGRNRLENDGATALA+ F+ +G+LEE+ MPQNGI H GITAL++AF NP L
Sbjct: 181 ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV 240
Query: 232 LNLNDNTXXXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKG 281
+NLNDNT L L+ ++ INFGDCL++S+GA A+A A +G
Sbjct: 241 INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRG 290
>CR456557-1|CAG30443.1| 587|Homo sapiens RANGAP1 protein.
Length = 587
Score = 255 bits (624), Expect = 3e-67
Identities = 138/290 (47%), Positives = 177/290 (61%), Gaps = 9/290 (3%)
Query: 1 MATFDLNSLNTVLDEPAQPETGVDFSGKSLKLDTAKDAQQIVDAINKCPNLQYLALTGNT 60
MA+ D+ L L + + F GKSLKL+TA+DA+ ++ I +L+ L L GNT
Sbjct: 1 MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT 60
Query: 61 LGVTAAHAISKALESHPELKIARFSDMFTGRMKTEIPPALSALGDGMIAAGARLAVLDLS 120
+GV AA I+KALE ELK +SDMFTGR++TEIPPAL +LG+G+I AGA+L LDLS
Sbjct: 61 VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS 120
Query: 121 DNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXXXXITGGXXXXXXXXXXXXXXX------ 174
DNAFGP GV+G LL+S C I GG
Sbjct: 121 DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL 180
Query: 175 ---VFIAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNH 231
VF+AGRNRLENDGATALA+ F+ +G+LEE+ MPQNGI H GITAL++AF NP L
Sbjct: 181 ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV 240
Query: 232 LNLNDNTXXXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKG 281
+NLNDNT L L+ ++ INFGDCL++S+GA A+A A +G
Sbjct: 241 INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRG 290
>BC041396-1|AAH41396.1| 587|Homo sapiens RANGAP1 protein protein.
Length = 587
Score = 255 bits (624), Expect = 3e-67
Identities = 138/290 (47%), Positives = 177/290 (61%), Gaps = 9/290 (3%)
Query: 1 MATFDLNSLNTVLDEPAQPETGVDFSGKSLKLDTAKDAQQIVDAINKCPNLQYLALTGNT 60
MA+ D+ L L + + F GKSLKL+TA+DA+ ++ I +L+ L L GNT
Sbjct: 1 MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT 60
Query: 61 LGVTAAHAISKALESHPELKIARFSDMFTGRMKTEIPPALSALGDGMIAAGARLAVLDLS 120
+GV AA I+KALE ELK +SDMFTGR++TEIPPAL +LG+G+I AGA+L LDLS
Sbjct: 61 VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS 120
Query: 121 DNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXXXXITGGXXXXXXXXXXXXXXX------ 174
DNAFGP GV+G LL+S C I GG
Sbjct: 121 DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL 180
Query: 175 ---VFIAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNH 231
VF+AGRNRLENDGATALA+ F+ +G+LEE+ MPQNGI H GITAL++AF NP L
Sbjct: 181 ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV 240
Query: 232 LNLNDNTXXXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKG 281
+NLNDNT L L+ ++ INFGDCL++S+GA A+A A +G
Sbjct: 241 INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRG 290
>BC014044-1|AAH14044.1| 587|Homo sapiens Ran GTPase activating
protein 1 protein.
Length = 587
Score = 255 bits (624), Expect = 3e-67
Identities = 138/290 (47%), Positives = 177/290 (61%), Gaps = 9/290 (3%)
Query: 1 MATFDLNSLNTVLDEPAQPETGVDFSGKSLKLDTAKDAQQIVDAINKCPNLQYLALTGNT 60
MA+ D+ L L + + F GKSLKL+TA+DA+ ++ I +L+ L L GNT
Sbjct: 1 MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT 60
Query: 61 LGVTAAHAISKALESHPELKIARFSDMFTGRMKTEIPPALSALGDGMIAAGARLAVLDLS 120
+GV AA I+KALE ELK +SDMFTGR++TEIPPAL +LG+G+I AGA+L LDLS
Sbjct: 61 VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS 120
Query: 121 DNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXXXXITGGXXXXXXXXXXXXXXX------ 174
DNAFGP GV+G LL+S C I GG
Sbjct: 121 DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL 180
Query: 175 ---VFIAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNH 231
VF+AGRNRLENDGATALA+ F+ +G+LEE+ MPQNGI H GITAL++AF NP L
Sbjct: 181 ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV 240
Query: 232 LNLNDNTXXXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKG 281
+NLNDNT L L+ ++ INFGDCL++S+GA A+A A +G
Sbjct: 241 INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRG 290
>AL035681-3|CAB63073.1| 587|Homo sapiens Ran GTPase activating
protein 1 protein.
Length = 587
Score = 255 bits (624), Expect = 3e-67
Identities = 138/290 (47%), Positives = 177/290 (61%), Gaps = 9/290 (3%)
Query: 1 MATFDLNSLNTVLDEPAQPETGVDFSGKSLKLDTAKDAQQIVDAINKCPNLQYLALTGNT 60
MA+ D+ L L + + F GKSLKL+TA+DA+ ++ I +L+ L L GNT
Sbjct: 1 MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT 60
Query: 61 LGVTAAHAISKALESHPELKIARFSDMFTGRMKTEIPPALSALGDGMIAAGARLAVLDLS 120
+GV AA I+KALE ELK +SDMFTGR++TEIPPAL +LG+G+I AGA+L LDLS
Sbjct: 61 VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS 120
Query: 121 DNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXXXXITGGXXXXXXXXXXXXXXX------ 174
DNAFGP GV+G LL+S C I GG
Sbjct: 121 DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL 180
Query: 175 ---VFIAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNH 231
VF+AGRNRLENDGATALA+ F+ +G+LEE+ MPQNGI H GITAL++AF NP L
Sbjct: 181 ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV 240
Query: 232 LNLNDNTXXXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKG 281
+NLNDNT L L+ ++ INFGDCL++S+GA A+A A +G
Sbjct: 241 INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRG 290
>AB058738-1|BAB47464.1| 623|Homo sapiens KIAA1835 protein protein.
Length = 623
Score = 255 bits (624), Expect = 3e-67
Identities = 138/290 (47%), Positives = 177/290 (61%), Gaps = 9/290 (3%)
Query: 1 MATFDLNSLNTVLDEPAQPETGVDFSGKSLKLDTAKDAQQIVDAINKCPNLQYLALTGNT 60
MA+ D+ L L + + F GKSLKL+TA+DA+ ++ I +L+ L L GNT
Sbjct: 37 MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDSLEALRLEGNT 96
Query: 61 LGVTAAHAISKALESHPELKIARFSDMFTGRMKTEIPPALSALGDGMIAAGARLAVLDLS 120
+GV AA I+KALE ELK +SDMFTGR++TEIPPAL +LG+G+I AGA+L LDLS
Sbjct: 97 VGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLGEGLITAGAQLVELDLS 156
Query: 121 DNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXXXXITGGXXXXXXXXXXXXXXX------ 174
DNAFGP GV+G LL+S C I GG
Sbjct: 157 DNAFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPL 216
Query: 175 ---VFIAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNH 231
VF+AGRNRLENDGATALA+ F+ +G+LEE+ MPQNGI H GITAL++AF NP L
Sbjct: 217 ALKVFVAGRNRLENDGATALAEAFRVIGTLEEVHMPQNGINHPGITALAQAFAVNPLLRV 276
Query: 232 LNLNDNTXXXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKG 281
+NLNDNT L L+ ++ INFGDCL++S+GA A+A A +G
Sbjct: 277 INLNDNTFTEKGAVAMAETLKTLRQVEVINFGDCLVRSKGAVAIADAIRG 326
>AY601811-1|AAT48367.1| 1065|Homo sapiens caterpiller 16.2 protein.
Length = 1065
Score = 52.0 bits (119), Expect = 5e-06
Identities = 58/265 (21%), Positives = 99/265 (37%), Gaps = 13/265 (4%)
Query: 21 TGVDFSGKSLKLDTAKDAQQIVDAINKCPNLQYLALTGNTLGVTAAHAISKALESHPELK 80
T +D G S+ AK + DA+ L L+L GNT+ A ++++AL S+ L
Sbjct: 697 TSLDLRGNSIGPQGAK---ALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLS 753
Query: 81 IARFSDMFTGRMKTEIPPALSALGDGMIAAGARLAVLDLSDNAFGPIGVEGLAKLLQSDV 140
+ G P + D + L L S N+ G G + LA+ L+
Sbjct: 754 MLHLQKNSIG------PMGAQRMADA-LKQNRSLKELMFSSNSIGDGGAKALAEALK--- 803
Query: 141 CSDXXXXXXXXXXXXITGGXXXXXXXXXXXXXXXVFIAGRNRLENDGATALAKVFQEMGS 200
+ G N + +GA A+A +
Sbjct: 804 VNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHALCANST 863
Query: 201 LEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXXXXXXXXXXXXLPRLKNLKSI 260
L+ + + N ++ G A++ A + N L L+L N L ++L S+
Sbjct: 864 LKNLDLTANLLHDQGARAIAVAVRENRTLTSLHLQWNFIQAGAAQALGQALQLNRSLTSL 923
Query: 261 NFGDCLLKSRGARALAKAFKGNSLL 285
+ + + GA A+A+A K N+ L
Sbjct: 924 DLQENAIGDDGACAVARALKVNTAL 948
Score = 51.6 bits (118), Expect = 7e-06
Identities = 61/259 (23%), Positives = 104/259 (40%), Gaps = 13/259 (5%)
Query: 38 AQQIVDAINKCPNLQYLALTGNTLGVTAAHAISKALESHPELKIARFSDMFTGRMKTEIP 97
AQ++ DA+ + +L+ L + N++G A A+++AL+ + L+ D+ + +
Sbjct: 767 AQRMADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESL---DLQSNSISDAGV 823
Query: 98 PALSALGDGMIAAGARLAVLDLSDNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXXXXIT 157
AL G + L L L +N+ P G + +A L ++ S
Sbjct: 824 AALM----GALCTNQTLLSLSLRENSISPEGAQAIAHALCAN--STLKNLDLTANLLHDQ 877
Query: 158 GGXXXXXXXXXXXXXXXVFIAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGIT 217
G + + N ++ A AL + Q SL + + +N I G
Sbjct: 878 GARAIAVAVRENRTLTSLHLQW-NFIQAGAAQALGQALQLNRSLTSLDLQENAIGDDGAC 936
Query: 218 ALSEAFKHNPALNHLNLNDNTXXXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAK 277
A++ A K N AL L L + L + L+ ++ + GA+ALA
Sbjct: 937 AVARALKVNTALTALYLQVASIGASGAQVLGEALAVNRTLEILDLRGNAIGVAGAKALAN 996
Query: 278 AFKGNSLLLEV---RNSLG 293
A K NS L + NSLG
Sbjct: 997 ALKVNSSLRRLNLQENSLG 1015
Score = 48.4 bits (110), Expect = 6e-05
Identities = 36/121 (29%), Positives = 53/121 (43%), Gaps = 3/121 (2%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXX 240
N++ N GA ALA+ SL + + N I G AL++A K N L L+L NT
Sbjct: 676 NQISNKGAKALARSLLVNRSLTSLDLRGNSIGPQGAKALADALKINRTLTSLSLQGNTVR 735
Query: 241 XXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEV---RNSLGNAAN 297
L + L ++ + GA+ +A A K N L E+ NS+G+
Sbjct: 736 DDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMADALKQNRSLKELMFSSNSIGDGGA 795
Query: 298 K 298
K
Sbjct: 796 K 796
Score = 44.8 bits (101), Expect = 8e-04
Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 3/118 (2%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXX 240
N + GA ALA + +L +++ N + G +++EA N L+ L+L N+
Sbjct: 704 NSIGPQGAKALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIG 763
Query: 241 XXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLL--LEVR-NSLGNA 295
L + ++LK + F + GA+ALA+A K N L L+++ NS+ +A
Sbjct: 764 PMGAQRMADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDLQSNSISDA 821
Score = 44.4 bits (100), Expect = 0.001
Identities = 38/191 (19%), Positives = 70/191 (36%), Gaps = 3/191 (1%)
Query: 98 PALSALGDGMIAAGARLAVLDLSDNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXXXXIT 157
P + LG + R+ + L++N G + LA+ L V
Sbjct: 652 PVMELLGSVLSGKDCRIQKISLAENQISNKGAKALARSLL--VNRSLTSLDLRGNSIGPQ 709
Query: 158 GGXXXXXXXXXXXXXXXVFIAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGIT 217
G + + G N + +DGA ++A+ +L + + +N I +G
Sbjct: 710 GAKALADALKINRTLTSLSLQG-NTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQ 768
Query: 218 ALSEAFKHNPALNHLNLNDNTXXXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAK 277
+++A K N +L L + N+ L + L+S++ + G AL
Sbjct: 769 RMADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDLQSNSISDAGVAALMG 828
Query: 278 AFKGNSLLLEV 288
A N LL +
Sbjct: 829 ALCTNQTLLSL 839
Score = 42.7 bits (96), Expect = 0.003
Identities = 50/200 (25%), Positives = 73/200 (36%), Gaps = 10/200 (5%)
Query: 38 AQQIVDAINKCPNLQYLALTGNTLGVTAAHAISKALESHPELKIARFSDMFTGRMKTEIP 97
AQ I A+ L+ L LT N L A AI+ A+ + L F
Sbjct: 851 AQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTSLHLQWNFIQA------ 904
Query: 98 PALSALGDGMIAAGARLAVLDLSDNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXXXXIT 157
A ALG + L LDL +NA G G +A+ L+ V + +
Sbjct: 905 GAAQALGQAL-QLNRSLTSLDLQENAIGDDGACAVARALK--VNTALTALYLQVASIGAS 961
Query: 158 GGXXXXXXXXXXXXXXXVFIAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGIT 217
G + + G N + GA ALA + SL + + +N + G
Sbjct: 962 GAQVLGEALAVNRTLEILDLRG-NAIGVAGAKALANALKVNSSLRRLNLQENSLGMDGAI 1020
Query: 218 ALSEAFKHNPALNHLNLNDN 237
++ A N L H+NL N
Sbjct: 1021 CIATALSGNHRLQHINLQGN 1040
Score = 41.1 bits (92), Expect = 0.010
Identities = 28/97 (28%), Positives = 42/97 (43%)
Query: 187 GATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXXXXXXXX 246
GA L + +LE + + N I G AL+ A K N +L LNL +N+
Sbjct: 962 GAQVLGEALAVNRTLEILDLRGNAIGVAGAKALANALKVNSSLRRLNLQENSLGMDGAIC 1021
Query: 247 XXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNS 283
L L+ IN + GAR +++A K N+
Sbjct: 1022 IATALSGNHRLQHINLQGNHIGDSGARMISEAIKTNA 1058
>AK074109-1|BAB84935.1| 499|Homo sapiens FLJ00180 protein protein.
Length = 499
Score = 52.0 bits (119), Expect = 5e-06
Identities = 58/265 (21%), Positives = 99/265 (37%), Gaps = 13/265 (4%)
Query: 21 TGVDFSGKSLKLDTAKDAQQIVDAINKCPNLQYLALTGNTLGVTAAHAISKALESHPELK 80
T +D G S+ AK + DA+ L L+L GNT+ A ++++AL S+ L
Sbjct: 131 TSLDLRGNSIGPQGAK---ALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLS 187
Query: 81 IARFSDMFTGRMKTEIPPALSALGDGMIAAGARLAVLDLSDNAFGPIGVEGLAKLLQSDV 140
+ G P + D + L L S N+ G G + LA+ L+
Sbjct: 188 MLHLQKNSIG------PMGAQRMADA-LKQNRSLKELMFSSNSIGDGGAKALAEALK--- 237
Query: 141 CSDXXXXXXXXXXXXITGGXXXXXXXXXXXXXXXVFIAGRNRLENDGATALAKVFQEMGS 200
+ G N + +GA A+A +
Sbjct: 238 VNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHALCANST 297
Query: 201 LEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXXXXXXXXXXXXLPRLKNLKSI 260
L+ + + N ++ G A++ A + N L L+L N L ++L S+
Sbjct: 298 LKNLDLTANLLHDQGARAIAVAVRENRTLTSLHLQWNFIQAGAAQALGQALQLNRSLTSL 357
Query: 261 NFGDCLLKSRGARALAKAFKGNSLL 285
+ + + GA A+A+A K N+ L
Sbjct: 358 DLQENAIGDDGACAVARALKVNTAL 382
Score = 51.6 bits (118), Expect = 7e-06
Identities = 61/259 (23%), Positives = 104/259 (40%), Gaps = 13/259 (5%)
Query: 38 AQQIVDAINKCPNLQYLALTGNTLGVTAAHAISKALESHPELKIARFSDMFTGRMKTEIP 97
AQ++ DA+ + +L+ L + N++G A A+++AL+ + L+ D+ + +
Sbjct: 201 AQRMADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESL---DLQSNSISDAGV 257
Query: 98 PALSALGDGMIAAGARLAVLDLSDNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXXXXIT 157
AL G + L L L +N+ P G + +A L ++ S
Sbjct: 258 AALM----GALCTNQTLLSLSLRENSISPEGAQAIAHALCAN--STLKNLDLTANLLHDQ 311
Query: 158 GGXXXXXXXXXXXXXXXVFIAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGIT 217
G + + N ++ A AL + Q SL + + +N I G
Sbjct: 312 GARAIAVAVRENRTLTSLHLQW-NFIQAGAAQALGQALQLNRSLTSLDLQENAIGDDGAC 370
Query: 218 ALSEAFKHNPALNHLNLNDNTXXXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAK 277
A++ A K N AL L L + L + L+ ++ + GA+ALA
Sbjct: 371 AVARALKVNTALTALYLQVASIGASGAQVLGEALAVNRTLEILDLRGNAIGVAGAKALAN 430
Query: 278 AFKGNSLLLEV---RNSLG 293
A K NS L + NSLG
Sbjct: 431 ALKVNSSLRRLNLQENSLG 449
Score = 48.4 bits (110), Expect = 6e-05
Identities = 36/121 (29%), Positives = 53/121 (43%), Gaps = 3/121 (2%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXX 240
N++ N GA ALA+ SL + + N I G AL++A K N L L+L NT
Sbjct: 110 NQISNKGAKALARSLLVNRSLTSLDLRGNSIGPQGAKALADALKINRTLTSLSLQGNTVR 169
Query: 241 XXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEV---RNSLGNAAN 297
L + L ++ + GA+ +A A K N L E+ NS+G+
Sbjct: 170 DDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMADALKQNRSLKELMFSSNSIGDGGA 229
Query: 298 K 298
K
Sbjct: 230 K 230
Score = 44.8 bits (101), Expect = 8e-04
Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 3/118 (2%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXX 240
N + GA ALA + +L +++ N + G +++EA N L+ L+L N+
Sbjct: 138 NSIGPQGAKALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIG 197
Query: 241 XXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLL--LEVR-NSLGNA 295
L + ++LK + F + GA+ALA+A K N L L+++ NS+ +A
Sbjct: 198 PMGAQRMADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDLQSNSISDA 255
Score = 44.4 bits (100), Expect = 0.001
Identities = 38/191 (19%), Positives = 70/191 (36%), Gaps = 3/191 (1%)
Query: 98 PALSALGDGMIAAGARLAVLDLSDNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXXXXIT 157
P + LG + R+ + L++N G + LA+ L V
Sbjct: 86 PVMELLGSVLSGKDCRIQKISLAENQISNKGAKALARSLL--VNRSLTSLDLRGNSIGPQ 143
Query: 158 GGXXXXXXXXXXXXXXXVFIAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGIT 217
G + + G N + +DGA ++A+ +L + + +N I +G
Sbjct: 144 GAKALADALKINRTLTSLSLQG-NTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQ 202
Query: 218 ALSEAFKHNPALNHLNLNDNTXXXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAK 277
+++A K N +L L + N+ L + L+S++ + G AL
Sbjct: 203 RMADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDLQSNSISDAGVAALMG 262
Query: 278 AFKGNSLLLEV 288
A N LL +
Sbjct: 263 ALCTNQTLLSL 273
Score = 42.7 bits (96), Expect = 0.003
Identities = 50/200 (25%), Positives = 73/200 (36%), Gaps = 10/200 (5%)
Query: 38 AQQIVDAINKCPNLQYLALTGNTLGVTAAHAISKALESHPELKIARFSDMFTGRMKTEIP 97
AQ I A+ L+ L LT N L A AI+ A+ + L F
Sbjct: 285 AQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTSLHLQWNFIQA------ 338
Query: 98 PALSALGDGMIAAGARLAVLDLSDNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXXXXIT 157
A ALG + L LDL +NA G G +A+ L+ V + +
Sbjct: 339 GAAQALGQAL-QLNRSLTSLDLQENAIGDDGACAVARALK--VNTALTALYLQVASIGAS 395
Query: 158 GGXXXXXXXXXXXXXXXVFIAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGIT 217
G + + G N + GA ALA + SL + + +N + G
Sbjct: 396 GAQVLGEALAVNRTLEILDLRG-NAIGVAGAKALANALKVNSSLRRLNLQENSLGMDGAI 454
Query: 218 ALSEAFKHNPALNHLNLNDN 237
++ A N L H+NL N
Sbjct: 455 CIATALSGNHRLQHINLQGN 474
Score = 41.1 bits (92), Expect = 0.010
Identities = 28/97 (28%), Positives = 42/97 (43%)
Query: 187 GATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXXXXXXXX 246
GA L + +LE + + N I G AL+ A K N +L LNL +N+
Sbjct: 396 GAQVLGEALAVNRTLEILDLRGNAIGVAGAKALANALKVNSSLRRLNLQENSLGMDGAIC 455
Query: 247 XXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNS 283
L L+ IN + GAR +++A K N+
Sbjct: 456 IATALSGNHRLQHINLQGNHIGDSGARMISEAIKTNA 492
>AF501291-1|AAM22459.1| 223|Homo sapiens CARD15-like protein
protein.
Length = 223
Score = 49.2 bits (112), Expect = 4e-05
Identities = 32/105 (30%), Positives = 48/105 (45%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXX 240
N + + GA ALA+ + LE + + N I G+ AL A N L L+L +N+
Sbjct: 88 NSIGDGGAKALAEALKVNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSLSLRENSIS 147
Query: 241 XXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLL 285
L LK+++ LL +GARA+A A + N L
Sbjct: 148 PEGAQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTL 192
Score = 44.8 bits (101), Expect = 8e-04
Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 3/118 (2%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXX 240
N + GA ALA + +L +++ N + G +++EA N L+ L+L N+
Sbjct: 4 NSIGPQGAKALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIG 63
Query: 241 XXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLL--LEVR-NSLGNA 295
L + ++LK + F + GA+ALA+A K N L L+++ NS+ +A
Sbjct: 64 PMGAQRMADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDLQSNSISDA 121
Score = 40.7 bits (91), Expect = 0.013
Identities = 25/108 (23%), Positives = 47/108 (43%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXX 240
N + +DGA ++A+ +L + + +N I +G +++A K N +L L + N+
Sbjct: 32 NTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMADALKQNRSLKELMFSSNSIG 91
Query: 241 XXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEV 288
L + L+S++ + G AL A N LL +
Sbjct: 92 DGGAKALAEALKVNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSL 139
>AJ303140-1|CAC42117.1| 1013|Homo sapiens LRR-containing protein
protein.
Length = 1013
Score = 48.8 bits (111), Expect = 5e-05
Identities = 38/126 (30%), Positives = 59/126 (46%), Gaps = 2/126 (1%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXX 240
NR+ ++GA ALA+ + SL +++ N I VG AL+ N L L L +N
Sbjct: 882 NRVGDEGAQALAEALGDHQSLRWLSLVGNNIGSVGAQALALMLAKNVMLEELCLEENHLQ 941
Query: 241 XXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEVRNSLGNAANKKS 300
L + +LK + + + GA AL +A + N +LEV GN + +
Sbjct: 942 DEGVCSLAEGLKKNSSLKILKLSNNCITYLGAEALLQALERNDTILEVW-LRGNTFSLEE 1000
Query: 301 LKDKLG 306
+ DKLG
Sbjct: 1001 V-DKLG 1005
Score = 36.3 bits (80), Expect = 0.27
Identities = 31/126 (24%), Positives = 59/126 (46%), Gaps = 7/126 (5%)
Query: 12 VLDEPAQPETGVDFSGKSLKLDTAKDAQQIVDAINKCPNLQYLALTGNTLGVTAAHAISK 71
VL E + T + F G + AQ + +A+ +L++L+L GN +G A A++
Sbjct: 863 VLAEGLRGNTSLQFLGFWGNRVGDEGAQALAEALGDHQSLRWLSLVGNNIGSVGAQALAL 922
Query: 72 ALESHPELKIARFSDMFTGRMKTEIPPALSALGDGMIAAGARLAVLDLSDNAFGPIGVEG 131
L + L+ + ++ E + +L +G+ + L +L LS+N +G E
Sbjct: 923 MLAKNVMLEELCLEE---NHLQDE---GVCSLAEGL-KKNSSLKILKLSNNCITYLGAEA 975
Query: 132 LAKLLQ 137
L + L+
Sbjct: 976 LLQALE 981
Score = 34.3 bits (75), Expect = 1.1
Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 7/106 (6%)
Query: 34 TAKDAQQIVDAINKCPNLQYLALTGNTLGVTAAHAISKALESHPELKIARFSDMFTGRMK 93
TA AQ + + + +LQ+L GN +G A A+++AL H L R+ + +
Sbjct: 857 TAAGAQVLAEGLRGNTSLQFLGFWGNRVGDEGAQALAEALGDHQSL---RWLSLVGNNIG 913
Query: 94 TEIPPALSALGDGMIAAGARLAVLDLSDNAFGPIGVEGLAKLLQSD 139
+ AL+ M+A L L L +N GV LA+ L+ +
Sbjct: 914 SVGAQALAL----MLAKNVMLEELCLEENHLQDEGVCSLAEGLKKN 955
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/88 (25%), Positives = 37/88 (42%)
Query: 198 MGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXXXXXXXXXXXXLPRLKNL 257
+G + + + N I GI L E H L L L +N L +N
Sbjct: 787 LGVCKALYLRDNNISDRGICKLIECALHCEQLQKLALFNNKLTDGCAHSMAKLLACRQNF 846
Query: 258 KSINFGDCLLKSRGARALAKAFKGNSLL 285
++ G+ + + GA+ LA+ +GN+ L
Sbjct: 847 LALRLGNNYITAAGAQVLAEGLRGNTSL 874
>AF178930-1|AAG33677.1| 1040|Homo sapiens NOD2 protein protein.
Length = 1040
Score = 48.8 bits (111), Expect = 5e-05
Identities = 38/126 (30%), Positives = 59/126 (46%), Gaps = 2/126 (1%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXX 240
NR+ ++GA ALA+ + SL +++ N I VG AL+ N L L L +N
Sbjct: 909 NRVGDEGAQALAEALGDHQSLRWLSLVGNNIGSVGAQALALMLAKNVMLEELCLEENHLQ 968
Query: 241 XXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEVRNSLGNAANKKS 300
L + +LK + + + GA AL +A + N +LEV GN + +
Sbjct: 969 DEGVCSLAEGLKKNSSLKILKLSNNCITYLGAEALLQALERNDTILEVW-LRGNTFSLEE 1027
Query: 301 LKDKLG 306
+ DKLG
Sbjct: 1028 V-DKLG 1032
Score = 36.3 bits (80), Expect = 0.27
Identities = 31/126 (24%), Positives = 59/126 (46%), Gaps = 7/126 (5%)
Query: 12 VLDEPAQPETGVDFSGKSLKLDTAKDAQQIVDAINKCPNLQYLALTGNTLGVTAAHAISK 71
VL E + T + F G + AQ + +A+ +L++L+L GN +G A A++
Sbjct: 890 VLAEGLRGNTSLQFLGFWGNRVGDEGAQALAEALGDHQSLRWLSLVGNNIGSVGAQALAL 949
Query: 72 ALESHPELKIARFSDMFTGRMKTEIPPALSALGDGMIAAGARLAVLDLSDNAFGPIGVEG 131
L + L+ + ++ E + +L +G+ + L +L LS+N +G E
Sbjct: 950 MLAKNVMLEELCLEE---NHLQDE---GVCSLAEGL-KKNSSLKILKLSNNCITYLGAEA 1002
Query: 132 LAKLLQ 137
L + L+
Sbjct: 1003 LLQALE 1008
Score = 34.3 bits (75), Expect = 1.1
Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 7/106 (6%)
Query: 34 TAKDAQQIVDAINKCPNLQYLALTGNTLGVTAAHAISKALESHPELKIARFSDMFTGRMK 93
TA AQ + + + +LQ+L GN +G A A+++AL H L R+ + +
Sbjct: 884 TAAGAQVLAEGLRGNTSLQFLGFWGNRVGDEGAQALAEALGDHQSL---RWLSLVGNNIG 940
Query: 94 TEIPPALSALGDGMIAAGARLAVLDLSDNAFGPIGVEGLAKLLQSD 139
+ AL+ M+A L L L +N GV LA+ L+ +
Sbjct: 941 SVGAQALAL----MLAKNVMLEELCLEENHLQDEGVCSLAEGLKKN 982
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/88 (25%), Positives = 37/88 (42%)
Query: 198 MGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXXXXXXXXXXXXLPRLKNL 257
+G + + + N I GI L E H L L L +N L +N
Sbjct: 814 LGVCKALYLRDNNISDRGICKLIECALHCEQLQKLALFNNKLTDGCAHSMAKLLACRQNF 873
Query: 258 KSINFGDCLLKSRGARALAKAFKGNSLL 285
++ G+ + + GA+ LA+ +GN+ L
Sbjct: 874 LALRLGNNYITAAGAQVLAEGLRGNTSL 901
>AF501292-1|AAM22460.1| 195|Homo sapiens CARD15-like protein
protein.
Length = 195
Score = 44.8 bits (101), Expect = 8e-04
Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 3/118 (2%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXX 240
N + GA ALA + +L +++ N + G +++EA N L+ L+L N+
Sbjct: 4 NSIGPQGAKALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIG 63
Query: 241 XXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLL--LEVR-NSLGNA 295
L + ++LK + F + GA+ALA+A K N L L+++ NS+ +A
Sbjct: 64 PMGAQRMADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDLQSNSISDA 121
Score = 40.7 bits (91), Expect = 0.013
Identities = 25/108 (23%), Positives = 47/108 (43%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXX 240
N + +DGA ++A+ +L + + +N I +G +++A K N +L L + N+
Sbjct: 32 NTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMADALKQNRSLKELMFSSNSIG 91
Query: 241 XXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEV 288
L + L+S++ + G AL A N LL +
Sbjct: 92 DGGAKALAEALKVNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSL 139
>BC040339-1|AAH40339.1| 953|Homo sapiens NOD1 protein protein.
Length = 953
Score = 43.6 bits (98), Expect = 0.002
Identities = 39/172 (22%), Positives = 66/172 (38%), Gaps = 3/172 (1%)
Query: 117 LDLSDNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXXXXITGGXXXXXXXXXXXXXXXVF 176
L L +N +G + K+L D C GG V
Sbjct: 761 LGLYNNQITDVGARYVTKIL--DECKGLTHLKLGKNKITSEGGKYLALAVKNSKSISEVG 818
Query: 177 IAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLND 236
+ G N++ ++GA A A+ + SL +++ NGI G +L+ A + N +L L L
Sbjct: 819 MWG-NQVGDEGAKAFAEALRNHPSLTTLSLASNGISTEGGKSLARALQQNTSLEILWLTQ 877
Query: 237 NTXXXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEV 288
N L + LK + + ++G LA A + N+ + E+
Sbjct: 878 NELNDEVAESLAEMLKVNQTLKHLWLIQNQITAKGTAQLADALQSNTGITEI 929
Score = 35.1 bits (77), Expect = 0.63
Identities = 24/93 (25%), Positives = 37/93 (39%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXX 240
N + +G +LA+ Q+ SLE + + QN + +L+E K N L HL L N
Sbjct: 850 NGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQTLKHLWLIQNQIT 909
Query: 241 XXXXXXXXXXLPRLKNLKSINFGDCLLKSRGAR 273
L + I L+K A+
Sbjct: 910 AKGTAQLADALQSNTGITEICLNGNLIKPEEAK 942
>AF149774-1|AAD43922.1| 953|Homo sapiens NOD1 protein protein.
Length = 953
Score = 43.6 bits (98), Expect = 0.002
Identities = 39/172 (22%), Positives = 66/172 (38%), Gaps = 3/172 (1%)
Query: 117 LDLSDNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXXXXITGGXXXXXXXXXXXXXXXVF 176
L L +N +G + K+L D C GG V
Sbjct: 761 LGLYNNQITDVGARYVTKIL--DECKGLTHLKLGKNKITSEGGKYLALAVKNSKSISEVG 818
Query: 177 IAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLND 236
+ G N++ ++GA A A+ + SL +++ NGI G +L+ A + N +L L L
Sbjct: 819 MWG-NQVGDEGAKAFAEALRNHPSLTTLSLASNGISTEGGKSLARALQQNTSLEILWLTQ 877
Query: 237 NTXXXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEV 288
N L + LK + + ++G LA A + N+ + E+
Sbjct: 878 NELNDEVAESLAEMLKVNQTLKHLWLIQNQITAKGTAQLADALQSNTGITEI 929
Score = 35.1 bits (77), Expect = 0.63
Identities = 24/93 (25%), Positives = 37/93 (39%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXX 240
N + +G +LA+ Q+ SLE + + QN + +L+E K N L HL L N
Sbjct: 850 NGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQTLKHLWLIQNQIT 909
Query: 241 XXXXXXXXXXLPRLKNLKSINFGDCLLKSRGAR 273
L + I L+K A+
Sbjct: 910 AKGTAQLADALQSNTGITEICLNGNLIKPEEAK 942
>AF126484-1|AAD29125.1| 953|Homo sapiens CARD4 protein.
Length = 953
Score = 43.6 bits (98), Expect = 0.002
Identities = 39/172 (22%), Positives = 66/172 (38%), Gaps = 3/172 (1%)
Query: 117 LDLSDNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXXXXITGGXXXXXXXXXXXXXXXVF 176
L L +N +G + K+L D C GG V
Sbjct: 761 LGLYNNQITDVGARYVTKIL--DECKGLTHLKLGKNKITSEGGKYLALAVKNSKSISEVG 818
Query: 177 IAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLND 236
+ G N++ ++GA A A+ + SL +++ NGI G +L+ A + N +L L L
Sbjct: 819 MWG-NQVGDEGAKAFAEALRNHPSLTTLSLASNGISTEGGKSLARALQQNTSLEILWLTQ 877
Query: 237 NTXXXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEV 288
N L + LK + + ++G LA A + N+ + E+
Sbjct: 878 NELNDEVAESLAEMLKVNQTLKHLWLIQNQITAKGTAQLADALQSNTGITEI 929
Score = 35.1 bits (77), Expect = 0.63
Identities = 24/93 (25%), Positives = 37/93 (39%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXX 240
N + +G +LA+ Q+ SLE + + QN + +L+E K N L HL L N
Sbjct: 850 NGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQTLKHLWLIQNQIT 909
Query: 241 XXXXXXXXXXLPRLKNLKSINFGDCLLKSRGAR 273
L + I L+K A+
Sbjct: 910 AKGTAQLADALQSNTGITEICLNGNLIKPEEAK 942
>AF113925-1|AAD28350.1| 953|Homo sapiens Nod1 protein.
Length = 953
Score = 43.6 bits (98), Expect = 0.002
Identities = 39/172 (22%), Positives = 66/172 (38%), Gaps = 3/172 (1%)
Query: 117 LDLSDNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXXXXITGGXXXXXXXXXXXXXXXVF 176
L L +N +G + K+L D C GG V
Sbjct: 761 LGLYNNQITDVGARYVTKIL--DECKGLTHLKLGKNKITSEGGKYLALAVKNSKSISEVG 818
Query: 177 IAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLND 236
+ G N++ ++GA A A+ + SL +++ NGI G +L+ A + N +L L L
Sbjct: 819 MWG-NQVGDEGAKAFAEALRNHPSLTTLSLASNGISTEGGKSLARALQQNTSLEILWLTQ 877
Query: 237 NTXXXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEV 288
N L + LK + + ++G LA A + N+ + E+
Sbjct: 878 NELNDEVAESLAEMLKVNQTLKHLWLIQNQITAKGTAQLADALQSNTGITEI 929
Score = 35.1 bits (77), Expect = 0.63
Identities = 24/93 (25%), Positives = 37/93 (39%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXX 240
N + +G +LA+ Q+ SLE + + QN + +L+E K N L HL L N
Sbjct: 850 NGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQTLKHLWLIQNQIT 909
Query: 241 XXXXXXXXXXLPRLKNLKSINFGDCLLKSRGAR 273
L + I L+K A+
Sbjct: 910 AKGTAQLADALQSNTGITEICLNGNLIKPEEAK 942
>AC006027-1|AAS46897.1| 953|Homo sapiens unknown protein.
Length = 953
Score = 43.6 bits (98), Expect = 0.002
Identities = 39/172 (22%), Positives = 66/172 (38%), Gaps = 3/172 (1%)
Query: 117 LDLSDNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXXXXITGGXXXXXXXXXXXXXXXVF 176
L L +N +G + K+L D C GG V
Sbjct: 761 LGLYNNQITDVGARYVTKIL--DECKGLTHLKLGKNKITSEGGKYLALAVKNSKSISEVG 818
Query: 177 IAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLND 236
+ G N++ ++GA A A+ + SL +++ NGI G +L+ A + N +L L L
Sbjct: 819 MWG-NQVGDEGAKAFAEALRNHPSLTTLSLASNGISTEGGKSLARALQQNTSLEILWLTQ 877
Query: 237 NTXXXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEV 288
N L + LK + + ++G LA A + N+ + E+
Sbjct: 878 NELNDEVAESLAEMLKVNQTLKHLWLIQNQITAKGTAQLADALQSNTGITEI 929
Score = 35.1 bits (77), Expect = 0.63
Identities = 24/93 (25%), Positives = 37/93 (39%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXX 240
N + +G +LA+ Q+ SLE + + QN + +L+E K N L HL L N
Sbjct: 850 NGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQTLKHLWLIQNQIT 909
Query: 241 XXXXXXXXXXLPRLKNLKSINFGDCLLKSRGAR 273
L + I L+K A+
Sbjct: 910 AKGTAQLADALQSNTGITEICLNGNLIKPEEAK 942
>AY051117-1|AAL12497.1| 1034|Homo sapiens cryopyrin protein.
Length = 1034
Score = 42.7 bits (96), Expect = 0.003
Identities = 46/206 (22%), Positives = 78/206 (37%), Gaps = 9/206 (4%)
Query: 34 TAKDAQQIVDAINKCPNLQYLALTGNTLGVTAAHAISKALESHPELKIARFSDMFTGRMK 93
T+ + + ++ +L L L+ N+LG + + L+ HP I R ++ GR
Sbjct: 724 TSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQ-HPGCNIRR---LWLGRCG 779
Query: 94 TEIPPALSALGDGMIAAGARLAVLDLSDNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXX 153
++++ +L LDLSDNA G G+ L L+ +C+
Sbjct: 780 LSHECCFDI--SLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCN--LKKLWLVSC 835
Query: 154 XXITGGXXXXXXXXXXXXXXXVFIAGRNRLENDGATALA-KVFQEMGSLEEIAMPQNGIY 212
+ G N L + G L K +L+++ + +G+
Sbjct: 836 CLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLT 895
Query: 213 HVGITALSEAFKHNPALNHLNLNDNT 238
V +ALS N L HL L NT
Sbjct: 896 SVCCSALSSVLSTNQNLTHLYLRGNT 921
>AL606804-9|CAI17153.1| 1036|Homo sapiens cold autoinflammatory
syndrome 1 protein.
Length = 1036
Score = 42.7 bits (96), Expect = 0.003
Identities = 46/206 (22%), Positives = 78/206 (37%), Gaps = 9/206 (4%)
Query: 34 TAKDAQQIVDAINKCPNLQYLALTGNTLGVTAAHAISKALESHPELKIARFSDMFTGRMK 93
T+ + + ++ +L L L+ N+LG + + L+ HP I R ++ GR
Sbjct: 726 TSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQ-HPGCNIRR---LWLGRCG 781
Query: 94 TEIPPALSALGDGMIAAGARLAVLDLSDNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXX 153
++++ +L LDLSDNA G G+ L L+ +C+
Sbjct: 782 LSHECCFDI--SLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCN--LKKLWLVSC 837
Query: 154 XXITGGXXXXXXXXXXXXXXXVFIAGRNRLENDGATALA-KVFQEMGSLEEIAMPQNGIY 212
+ G N L + G L K +L+++ + +G+
Sbjct: 838 CLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLT 897
Query: 213 HVGITALSEAFKHNPALNHLNLNDNT 238
V +ALS N L HL L NT
Sbjct: 898 SVCCSALSSVLSTNQNLTHLYLRGNT 923
>AF468522-1|AAL78632.1| 1036|Homo sapiens NALP3 long isoform
protein.
Length = 1036
Score = 42.7 bits (96), Expect = 0.003
Identities = 46/206 (22%), Positives = 78/206 (37%), Gaps = 9/206 (4%)
Query: 34 TAKDAQQIVDAINKCPNLQYLALTGNTLGVTAAHAISKALESHPELKIARFSDMFTGRMK 93
T+ + + ++ +L L L+ N+LG + + L+ HP I R ++ GR
Sbjct: 726 TSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQ-HPGCNIRR---LWLGRCG 781
Query: 94 TEIPPALSALGDGMIAAGARLAVLDLSDNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXX 153
++++ +L LDLSDNA G G+ L L+ +C+
Sbjct: 782 LSHECCFDI--SLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCN--LKKLWLVSC 837
Query: 154 XXITGGXXXXXXXXXXXXXXXVFIAGRNRLENDGATALA-KVFQEMGSLEEIAMPQNGIY 212
+ G N L + G L K +L+++ + +G+
Sbjct: 838 CLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLT 897
Query: 213 HVGITALSEAFKHNPALNHLNLNDNT 238
V +ALS N L HL L NT
Sbjct: 898 SVCCSALSSVLSTNQNLTHLYLRGNT 923
>AF420469-1|AAL65136.1| 1034|Homo sapiens PYRIN-containing
APAF1-like protein 1 protein.
Length = 1034
Score = 42.7 bits (96), Expect = 0.003
Identities = 46/206 (22%), Positives = 78/206 (37%), Gaps = 9/206 (4%)
Query: 34 TAKDAQQIVDAINKCPNLQYLALTGNTLGVTAAHAISKALESHPELKIARFSDMFTGRMK 93
T+ + + ++ +L L L+ N+LG + + L+ HP I R ++ GR
Sbjct: 724 TSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQ-HPGCNIRR---LWLGRCG 779
Query: 94 TEIPPALSALGDGMIAAGARLAVLDLSDNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXX 153
++++ +L LDLSDNA G G+ L L+ +C+
Sbjct: 780 LSHECCFDI--SLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCN--LKKLWLVSC 835
Query: 154 XXITGGXXXXXXXXXXXXXXXVFIAGRNRLENDGATALA-KVFQEMGSLEEIAMPQNGIY 212
+ G N L + G L K +L+++ + +G+
Sbjct: 836 CLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLT 895
Query: 213 HVGITALSEAFKHNPALNHLNLNDNT 238
V +ALS N L HL L NT
Sbjct: 896 SVCCSALSSVLSTNQNLTHLYLRGNT 921
>AF410477-1|AAL33908.1| 1034|Homo sapiens cryopyrin protein.
Length = 1034
Score = 42.7 bits (96), Expect = 0.003
Identities = 46/206 (22%), Positives = 78/206 (37%), Gaps = 9/206 (4%)
Query: 34 TAKDAQQIVDAINKCPNLQYLALTGNTLGVTAAHAISKALESHPELKIARFSDMFTGRMK 93
T+ + + ++ +L L L+ N+LG + + L+ HP I R ++ GR
Sbjct: 724 TSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQ-HPGCNIRR---LWLGRCG 779
Query: 94 TEIPPALSALGDGMIAAGARLAVLDLSDNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXX 153
++++ +L LDLSDNA G G+ L L+ +C+
Sbjct: 780 LSHECCFDI--SLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCN--LKKLWLVSC 835
Query: 154 XXITGGXXXXXXXXXXXXXXXVFIAGRNRLENDGATALA-KVFQEMGSLEEIAMPQNGIY 212
+ G N L + G L K +L+++ + +G+
Sbjct: 836 CLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLT 895
Query: 213 HVGITALSEAFKHNPALNHLNLNDNT 238
V +ALS N L HL L NT
Sbjct: 896 SVCCSALSSVLSTNQNLTHLYLRGNT 921
>AY154468-1|AAO18164.1| 1043|Homo sapiens NALP13 protein.
Length = 1043
Score = 39.9 bits (89), Expect = 0.022
Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 2/106 (1%)
Query: 179 GRNRLENDGATAL-AKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDN 237
G NRL++DG L A + +LE + + + LS+A N +L HLNL+ N
Sbjct: 846 GFNRLQDDGIKLLCAALTHPKCALERLELWFCQLAAPACKHLSDALLQNRSLTHLNLSKN 905
Query: 238 TXXXXXXXXXXXXLPRLK-NLKSINFGDCLLKSRGARALAKAFKGN 282
+ L R NL+S+N C G LA A N
Sbjct: 906 SLRDEGVKFLCEALGRPDGNLQSLNLSGCSFTREGCGELANALSHN 951
>BC117211-1|AAI17212.1| 979|Homo sapiens NLRP3 protein protein.
Length = 979
Score = 39.1 bits (87), Expect = 0.039
Identities = 32/133 (24%), Positives = 51/133 (38%), Gaps = 3/133 (2%)
Query: 107 MIAAGARLAVLDLSDNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXXXXITGGXXXXXXX 166
++++ +L LDLSDNA G G+ L L+ +C+ +
Sbjct: 736 VLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCN--LKKLWLVSCCLTSACCQDLASV 793
Query: 167 XXXXXXXXVFIAGRNRLENDGATALA-KVFQEMGSLEEIAMPQNGIYHVGITALSEAFKH 225
G N L + G L K +L+++ + +G+ V +ALS
Sbjct: 794 LSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLST 853
Query: 226 NPALNHLNLNDNT 238
N L HL L NT
Sbjct: 854 NQNLTHLYLRGNT 866
>AY422168-1|AAQ98889.1| 977|Homo sapiens cryopyrin deletion 4
isoform protein.
Length = 977
Score = 39.1 bits (87), Expect = 0.039
Identities = 32/133 (24%), Positives = 51/133 (38%), Gaps = 3/133 (2%)
Query: 107 MIAAGARLAVLDLSDNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXXXXITGGXXXXXXX 166
++++ +L LDLSDNA G G+ L L+ +C+ +
Sbjct: 734 VLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCN--LKKLWLVSCCLTSACCQDLASV 791
Query: 167 XXXXXXXXVFIAGRNRLENDGATALA-KVFQEMGSLEEIAMPQNGIYHVGITALSEAFKH 225
G N L + G L K +L+++ + +G+ V +ALS
Sbjct: 792 LSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLST 851
Query: 226 NPALNHLNLNDNT 238
N L HL L NT
Sbjct: 852 NQNLTHLYLRGNT 864
>AL606804-11|CAI17155.1| 977|Homo sapiens cold autoinflammatory
syndrome 1 protein.
Length = 977
Score = 39.1 bits (87), Expect = 0.039
Identities = 32/133 (24%), Positives = 51/133 (38%), Gaps = 3/133 (2%)
Query: 107 MIAAGARLAVLDLSDNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXXXXITGGXXXXXXX 166
++++ +L LDLSDNA G G+ L L+ +C+ +
Sbjct: 734 VLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCN--LKKLWLVSCCLTSACCQDLASV 791
Query: 167 XXXXXXXXVFIAGRNRLENDGATALA-KVFQEMGSLEEIAMPQNGIYHVGITALSEAFKH 225
G N L + G L K +L+++ + +G+ V +ALS
Sbjct: 792 LSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLST 851
Query: 226 NPALNHLNLNDNT 238
N L HL L NT
Sbjct: 852 NQNLTHLYLRGNT 864
>X74301-1|CAA52354.1| 1130|Homo sapiens (MHC) class II transactivator
protein.
Length = 1130
Score = 38.3 bits (85), Expect = 0.068
Identities = 26/101 (25%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPA-LNHLNLNDNTX 239
N++ ++G + L+ F ++ SLE + + QN I +G L+EA A L L+L +N
Sbjct: 997 NKIGDEGVSQLSATFPQLKSLETLNLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCI 1056
Query: 240 XXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFK 280
LP + +L+ ++ + GA+ LA + +
Sbjct: 1057 CDVGAESLARVLPDMVSLRVMDVQYNKFTAAGAQQLAASLR 1097
>U18259-1|AAA88861.1| 1130|Homo sapiens MHC class II transactivator
CIITA protein.
Length = 1130
Score = 38.3 bits (85), Expect = 0.068
Identities = 26/101 (25%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPA-LNHLNLNDNTX 239
N++ ++G + L+ F ++ SLE + + QN I +G L+EA A L L+L +N
Sbjct: 997 NKIGDEGVSQLSATFPQLKSLETLNLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCI 1056
Query: 240 XXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFK 280
LP + +L+ ++ + GA+ LA + +
Sbjct: 1057 CDVGAESLARVLPDMVSLRVMDVQYNKFTAAGAQQLAASLR 1097
>AY699071-1|AAU06586.1| 1107|Homo sapiens CIITA IV protein.
Length = 1107
Score = 38.3 bits (85), Expect = 0.068
Identities = 26/101 (25%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPA-LNHLNLNDNTX 239
N++ ++G + L+ F ++ SLE + + QN I +G L+EA A L L+L +N
Sbjct: 974 NKIGDEGVSQLSATFPQLKSLETLNLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCI 1033
Query: 240 XXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFK 280
LP + +L+ ++ + GA+ LA + +
Sbjct: 1034 CDVGAESLARVLPDMVSLRVMDVQYNKFTAAGAQQLAASLR 1074
>AY084054-1|AAM15723.1| 546|Homo sapiens MHC class II
transactivator CIITAmed protein.
Length = 546
Score = 38.3 bits (85), Expect = 0.068
Identities = 26/101 (25%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPA-LNHLNLNDNTX 239
N++ ++G + L+ F ++ SLE + + QN I +G L+EA A L L+L +N
Sbjct: 413 NKIGDEGVSQLSATFPQLKSLETLNLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCI 472
Query: 240 XXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFK 280
LP + +L+ ++ + GA+ LA + +
Sbjct: 473 CDVGAESLARVLPDMVSLRVMDVQYNKFTAAGAQQLAASLR 513
>AL160037-1|CAH72024.1| 1371|Homo sapiens leucine rich repeat
containing 16 protein.
Length = 1371
Score = 37.9 bits (84), Expect = 0.090
Identities = 26/106 (24%), Positives = 42/106 (39%), Gaps = 3/106 (2%)
Query: 182 RLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNP--ALNHLNLNDNTX 239
+L D + +V LEE+ + G+ L+ A HNP L+ +NL N
Sbjct: 229 KLSTDVCEQILRVVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPL 288
Query: 240 XXXXXXXXXXXLPRL-KNLKSINFGDCLLKSRGARALAKAFKGNSL 284
+L K LK +N L +G +L+++ N L
Sbjct: 289 EDRGVSSLSIQFAKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPL 334
Score = 31.5 bits (68), Expect = 7.8
Identities = 30/122 (24%), Positives = 56/122 (45%), Gaps = 15/122 (12%)
Query: 21 TGVDFSGKSLKLDTAKDAQQIVDAINKCPNLQYLALTGNTLGVTAAHAISKALES----- 75
T +D S L+ D ++ ++K ++Q+LAL G + ++ L++
Sbjct: 485 TSLDISDNGLE----SDLSTLIVWLSKNRSIQHLAL-GKNFNNMKSKNLTPVLDNLVQMI 539
Query: 76 HPELKIARFSDMFTGRMKTEIPPALSALGDGMIAAGARLAVLDLSDNAFGPIGVEGLAKL 135
E + + ++KTE+ ++ALG + L +D+S N G +G + LAK
Sbjct: 540 QDEESPLQSLSLADSKLKTEVTIIINALG-----SNTSLTKVDISGNGMGDMGAKMLAKA 594
Query: 136 LQ 137
LQ
Sbjct: 595 LQ 596
>AL024509-3|CAI21665.1| 1371|Homo sapiens leucine rich repeat
containing 16 protein.
Length = 1371
Score = 37.9 bits (84), Expect = 0.090
Identities = 26/106 (24%), Positives = 42/106 (39%), Gaps = 3/106 (2%)
Query: 182 RLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNP--ALNHLNLNDNTX 239
+L D + +V LEE+ + G+ L+ A HNP L+ +NL N
Sbjct: 229 KLSTDVCEQILRVVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPL 288
Query: 240 XXXXXXXXXXXLPRL-KNLKSINFGDCLLKSRGARALAKAFKGNSL 284
+L K LK +N L +G +L+++ N L
Sbjct: 289 EDRGVSSLSIQFAKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPL 334
Score = 31.5 bits (68), Expect = 7.8
Identities = 30/122 (24%), Positives = 56/122 (45%), Gaps = 15/122 (12%)
Query: 21 TGVDFSGKSLKLDTAKDAQQIVDAINKCPNLQYLALTGNTLGVTAAHAISKALES----- 75
T +D S L+ D ++ ++K ++Q+LAL G + ++ L++
Sbjct: 485 TSLDISDNGLE----SDLSTLIVWLSKNRSIQHLAL-GKNFNNMKSKNLTPVLDNLVQMI 539
Query: 76 HPELKIARFSDMFTGRMKTEIPPALSALGDGMIAAGARLAVLDLSDNAFGPIGVEGLAKL 135
E + + ++KTE+ ++ALG + L +D+S N G +G + LAK
Sbjct: 540 QDEESPLQSLSLADSKLKTEVTIIINALG-----SNTSLTKVDISGNGMGDMGAKMLAKA 594
Query: 136 LQ 137
LQ
Sbjct: 595 LQ 596
>AL022170-1|CAI21583.1| 1371|Homo sapiens leucine rich repeat
containing 16 protein.
Length = 1371
Score = 37.9 bits (84), Expect = 0.090
Identities = 26/106 (24%), Positives = 42/106 (39%), Gaps = 3/106 (2%)
Query: 182 RLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNP--ALNHLNLNDNTX 239
+L D + +V LEE+ + G+ L+ A HNP L+ +NL N
Sbjct: 229 KLSTDVCEQILRVVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPL 288
Query: 240 XXXXXXXXXXXLPRL-KNLKSINFGDCLLKSRGARALAKAFKGNSL 284
+L K LK +N L +G +L+++ N L
Sbjct: 289 EDRGVSSLSIQFAKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPL 334
Score = 31.5 bits (68), Expect = 7.8
Identities = 30/122 (24%), Positives = 56/122 (45%), Gaps = 15/122 (12%)
Query: 21 TGVDFSGKSLKLDTAKDAQQIVDAINKCPNLQYLALTGNTLGVTAAHAISKALES----- 75
T +D S L+ D ++ ++K ++Q+LAL G + ++ L++
Sbjct: 485 TSLDISDNGLE----SDLSTLIVWLSKNRSIQHLAL-GKNFNNMKSKNLTPVLDNLVQMI 539
Query: 76 HPELKIARFSDMFTGRMKTEIPPALSALGDGMIAAGARLAVLDLSDNAFGPIGVEGLAKL 135
E + + ++KTE+ ++ALG + L +D+S N G +G + LAK
Sbjct: 540 QDEESPLQSLSLADSKLKTEVTIIINALG-----SNTSLTKVDISGNGMGDMGAKMLAKA 594
Query: 136 LQ 137
LQ
Sbjct: 595 LQ 596
>AK125696-1|BAC86250.1| 499|Homo sapiens protein ( Homo sapiens
cDNA FLJ43708 fis, clone TESOP2001953. ).
Length = 499
Score = 37.9 bits (84), Expect = 0.090
Identities = 26/106 (24%), Positives = 42/106 (39%), Gaps = 3/106 (2%)
Query: 182 RLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNP--ALNHLNLNDNTX 239
+L D + +V LEE+ + G+ L+ A HNP L+ +NL N
Sbjct: 229 KLSTDVCEQILRVVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPL 288
Query: 240 XXXXXXXXXXXLPRL-KNLKSINFGDCLLKSRGARALAKAFKGNSL 284
+L K LK +N L +G +L+++ N L
Sbjct: 289 EDRGVSSLSIQFAKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPL 334
>EF064747-1|ABK41930.1| 1130|Homo sapiens class II, major
histocompatibility complex, transactivator protein.
Length = 1130
Score = 37.5 bits (83), Expect = 0.12
Identities = 26/101 (25%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPA-LNHLNLNDNTX 239
N++ ++G + L+ F ++ SLE ++ QN I +G L+EA A L L+L +N
Sbjct: 997 NKIGDEGVSQLSATFPQLKSLETRSLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCI 1056
Query: 240 XXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFK 280
LP + +L+ ++ + GA+ LA + +
Sbjct: 1057 CDVGAESLARVLPDMVSLRVMDVQYNKFTAAGAQQLAASLR 1097
>BC032841-1|AAH32841.1| 419|Homo sapiens leucine rich repeat
containing 34 protein.
Length = 419
Score = 35.1 bits (77), Expect = 0.63
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Query: 181 NRLENDGATALAKVFQEMG-SLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDN 237
NR+EN GA L++ SL+ +++ N I G+ ALS++ K N +H+ + N
Sbjct: 287 NRIENAGANYLSETLTSHNRSLKALSVVSNNIEGEGLVALSQSMKTNLTFSHIYIWGN 344
Score = 33.1 bits (72), Expect = 2.6
Identities = 47/194 (24%), Positives = 69/194 (35%), Gaps = 12/194 (6%)
Query: 45 INKCPNLQYLALTGNTLGVTAAHAISKALESHPELKIARFSDMFTGRMKTEIPPALSALG 104
+ K NL YL L N +G I+K L + LK R TG +I
Sbjct: 134 LQKQLNLIYLNLMFNDIGPEGGELIAKVLHKNRTLKYLRM----TGN---KIENKGGMFF 186
Query: 105 DGMIAAGARLAVLDLSDNAFGPIGVEGLAKLLQSDVCSDXXXXXXXXXXXXITGGXXXXX 164
M+ + L LDL D V + ++L+ + C G
Sbjct: 187 AAMLQINSSLEKLDLGDCDLEESTVH-VGRMLKENHC---LVALHMCKHDIKNSGIQQLC 242
Query: 165 XXXXXXXXXXVFIAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAF- 223
N++ +DG LA V + +LE I + N I + G LSE
Sbjct: 243 DALYLNSSLRYLDVSCNKITHDGMVYLADVLKSNTTLEVIDLSFNRIENAGANYLSETLT 302
Query: 224 KHNPALNHLNLNDN 237
HN +L L++ N
Sbjct: 303 SHNRSLKALSVVSN 316
Score = 31.5 bits (68), Expect = 7.8
Identities = 23/104 (22%), Positives = 45/104 (43%), Gaps = 1/104 (0%)
Query: 180 RNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTX 239
++ ++N G L SL + + N I H G+ L++ K N L ++L+ N
Sbjct: 230 KHDIKNSGIQQLCDALYLNSSLRYLDVSCNKITHDGMVYLADVLKSNTTLEVIDLSFNRI 289
Query: 240 XXXXXXXXXXXL-PRLKNLKSINFGDCLLKSRGARALAKAFKGN 282
L ++LK+++ ++ G AL+++ K N
Sbjct: 290 ENAGANYLSETLTSHNRSLKALSVVSNNIEGEGLVALSQSMKTN 333
>BC008782-1|AAH08782.1| 1219|Homo sapiens nuclear factor of kappa
light polypeptide gene enhancer in B-cells inhibitor-li
protein.
Length = 1219
Score = 34.7 bits (76), Expect = 0.84
Identities = 38/119 (31%), Positives = 50/119 (42%), Gaps = 9/119 (7%)
Query: 22 GVDFSGKSLKLDTAKDAQQIVDAINKCPNLQYLALTGNTLGVTAAHAISKALESHPELKI 81
G+ FS SL LD A+ ++ A+ L+ L L GN LG + AL + P L +
Sbjct: 885 GLSFSACSLALDQAQ-LTPLLRALKLHTALRELRLAGNRLGDKCVAELVAALGTMPSLAL 943
Query: 82 ARFSDMFTGRMKTEIPPALSALGDGM--IAAGARLAVLDLSDNAFGPIGVEGLAKLLQS 138
S G P L L G+ A L LDLS N G + LA LL +
Sbjct: 944 LDLSSNHLG------PEGLRQLAMGLPGQATLQSLEELDLSMNPLGDGCGQSLASLLHA 996
>AB209126-1|BAD92363.1| 897|Homo sapiens I-kappa-B-related protein
variant protein.
Length = 897
Score = 34.7 bits (76), Expect = 0.84
Identities = 38/119 (31%), Positives = 50/119 (42%), Gaps = 9/119 (7%)
Query: 22 GVDFSGKSLKLDTAKDAQQIVDAINKCPNLQYLALTGNTLGVTAAHAISKALESHPELKI 81
G+ FS SL LD A+ ++ A+ L+ L L GN LG + AL + P L +
Sbjct: 744 GLSFSACSLALDQAQ-LTPLLRALKLHTALRELRLAGNRLGDKCVAELVAALGTMPSLAL 802
Query: 82 ARFSDMFTGRMKTEIPPALSALGDGM--IAAGARLAVLDLSDNAFGPIGVEGLAKLLQS 138
S G P L L G+ A L LDLS N G + LA LL +
Sbjct: 803 LDLSSNHLG------PEGLRQLAMGLPGQATLQSLEELDLSMNPLGDGCGQSLASLLHA 855
>EF452236-1|ABO40479.1| 1866|Homo sapiens NOD4 protein.
Length = 1866
Score = 34.3 bits (75), Expect = 1.1
Identities = 30/134 (22%), Positives = 51/134 (38%)
Query: 180 RNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTX 239
RN + + G L++ + SLEE+ + N I G+ L+ P L ++L+ N+
Sbjct: 1587 RNSIGDVGCCHLSEALRAATSLEELDLSHNQIGDAGVQHLATILPGLPELRKIDLSGNSI 1646
Query: 240 XXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEVRNSLGNAANKK 299
L + L+ + G L A LA+ + +L + S
Sbjct: 1647 SSAGGVQLAESLVLCRRLEELMLGCNALGDPTALGLAQELPQHLRVLHLPFSHLGPGGAL 1706
Query: 300 SLKDKLGASAELSD 313
SL L S L +
Sbjct: 1707 SLAQALDGSPHLEE 1720
>BC063566-1|AAH63566.1| 837|Homo sapiens NLRC5 protein protein.
Length = 837
Score = 34.3 bits (75), Expect = 1.1
Identities = 30/134 (22%), Positives = 51/134 (38%)
Query: 180 RNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTX 239
RN + + G L++ + SLEE+ + N I G+ L+ P L ++L+ N+
Sbjct: 558 RNSIGDVGCCHLSEALRAATSLEELDLSHNQIGDAGVQHLATILPGLPELRKIDLSGNSI 617
Query: 240 XXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEVRNSLGNAANKK 299
L + L+ + G L A LA+ + +L + S
Sbjct: 618 SSAGGVQLAESLVLCRRLEELMLGCNALGDPTALGLAQELPQHLRVLHLPFSHLGPGGAL 677
Query: 300 SLKDKLGASAELSD 313
SL L S L +
Sbjct: 678 SLAQALDGSPHLEE 691
>BC035022-1|AAH35022.1| 501|Homo sapiens hypothetical protein
MGC33600 protein.
Length = 501
Score = 34.3 bits (75), Expect = 1.1
Identities = 30/118 (25%), Positives = 44/118 (37%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXX 240
N++ GA +LA +L + + N I G AL+ A + N L L+L N
Sbjct: 344 NQVRAPGAQSLAHALAHNTNLISLNLRLNCIEDEGGQALAHALQTNKCLTTLHLGGNELS 403
Query: 241 XXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEVRNSLGNAANK 298
L L SIN + G + L + N LLE L + A +
Sbjct: 404 EPTATLLSQVLAINTTLTSINLSCNHIGLDGGKQLLEGMSDNKTLLEFDLRLSDVAQE 461
Score = 31.5 bits (68), Expect = 7.8
Identities = 30/126 (23%), Positives = 49/126 (38%), Gaps = 4/126 (3%)
Query: 180 RNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTX 239
+N + + GA AK+ L + + N + G +L+ A HN L LNL N
Sbjct: 316 QNLIGDRGARGAAKLLSH-SRLRVLNLANNQVRAPGAQSLAHALAHNTNLISLNLRLNCI 374
Query: 240 XXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEVR---NSLGNAA 296
L K L +++ G L A L++ N+ L + N +G
Sbjct: 375 EDEGGQALAHALQTNKCLTTLHLGGNELSEPTATLLSQVLAINTTLTSINLSCNHIGLDG 434
Query: 297 NKKSLK 302
K+ L+
Sbjct: 435 GKQLLE 440
>AL353588-2|CAI40746.1| 501|Homo sapiens protein ( Human DNA
sequence from clone RP11-444E17 on chromosome 6. ).
Length = 501
Score = 34.3 bits (75), Expect = 1.1
Identities = 30/118 (25%), Positives = 44/118 (37%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTXX 240
N++ GA +LA +L + + N I G AL+ A + N L L+L N
Sbjct: 344 NQVRAPGAQSLAHALAHNTNLISLNLRLNCIEDEGGQALAHALQTNKCLTTLHLGGNELS 403
Query: 241 XXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEVRNSLGNAANK 298
L L SIN + G + L + N LLE L + A +
Sbjct: 404 EPTATLLSQVLAINTTLTSINLSCNHIGLDGGKQLLEGMSDNKTLLEFDLRLSDVAQE 461
Score = 31.5 bits (68), Expect = 7.8
Identities = 30/126 (23%), Positives = 49/126 (38%), Gaps = 4/126 (3%)
Query: 180 RNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTX 239
+N + + GA AK+ L + + N + G +L+ A HN L LNL N
Sbjct: 316 QNLIGDRGARGAAKLLSH-SRLRVLNLANNQVRAPGAQSLAHALAHNTNLISLNLRLNCI 374
Query: 240 XXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEVR---NSLGNAA 296
L K L +++ G L A L++ N+ L + N +G
Sbjct: 375 EDEGGQALAHALQTNKCLTTLHLGGNELSEPTATLLSQVLAINTTLTSINLSCNHIGLDG 434
Query: 297 NKKSLK 302
K+ L+
Sbjct: 435 GKQLLE 440
>AF389420-1|AAO59377.1| 1866|Homo sapiens NOD27 protein.
Length = 1866
Score = 34.3 bits (75), Expect = 1.1
Identities = 30/134 (22%), Positives = 51/134 (38%)
Query: 180 RNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTX 239
RN + + G L++ + SLEE+ + N I G+ L+ P L ++L+ N+
Sbjct: 1587 RNSIGDVGCCHLSEALRAATSLEELDLSHNQIGDAGVQHLATILPGLPELRKIDLSGNSI 1646
Query: 240 XXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEVRNSLGNAANKK 299
L + L+ + G L A LA+ + +L + S
Sbjct: 1647 SSAGGVQLAESLVLCRRLEELMLGCNALGDPTALGLAQELPQHLRVLHLPFSHLGPGGAL 1706
Query: 300 SLKDKLGASAELSD 313
SL L S L +
Sbjct: 1707 SLAQALDGSPHLEE 1720
>AB113647-1|BAD26751.1| 1475|Homo sapiens RGD, leucine-rich repeat,
tropomodulin and proline-rich containing protein
protein.
Length = 1475
Score = 33.5 bits (73), Expect = 1.9
Identities = 23/66 (34%), Positives = 37/66 (56%), Gaps = 6/66 (9%)
Query: 177 IAGRNRLENDGATALAKVFQEM-GSLEEIAMPQNGIYHVGITALSEAFKHNPA----LNH 231
+AG N L++ G TAL++ + G+L +++ Q G+ G+ AL A N A L H
Sbjct: 322 LAG-NLLDDRGMTALSRHLERCPGALRRLSLAQTGLTPRGMRALGRALATNAAFDSTLTH 380
Query: 232 LNLNDN 237
L+L+ N
Sbjct: 381 LDLSGN 386
>AY154464-1|AAO18160.1| 986|Homo sapiens NALP9 protein.
Length = 986
Score = 33.1 bits (72), Expect = 2.6
Identities = 26/105 (24%), Positives = 44/105 (41%), Gaps = 1/105 (0%)
Query: 177 IAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNP-ALNHLNLN 235
I G+ + ++ +A V L+ +++ +N + G+T L EA KH+ AL L L
Sbjct: 720 ILGKCDISSEVCEDIASVLACNSKLKHLSLVENPLRDEGMTLLCEALKHSHCALERLMLM 779
Query: 236 DNTXXXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFK 280
L K+L ++ G L+ G +L A K
Sbjct: 780 YCCLTSVSCDSISEVLLCSKSLSLLDLGSNALEDNGVASLCAALK 824
>AF165217-1|AAF01277.1| 345|Homo sapiens Sk-tropomodulin protein.
Length = 345
Score = 33.1 bits (72), Expect = 2.6
Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 5/102 (4%)
Query: 191 LAKVFQEMGSLEEIAMPQNGIYHVGITALSE---AFKHNPALNHLNLNDNTXXXXXXXXX 247
L +V LEE+ + N I + I LSE A K N + +L
Sbjct: 187 LKRVRSNDKELEEVNL--NNIQDIPIPMLSELCEAMKANTYVRSFSLVATRSGDPIANAV 244
Query: 248 XXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEVR 289
L ++L+S+N + S G A+ KA + N+ L+E+R
Sbjct: 245 ADMLRENRSLQSLNIESNFISSTGLMAVLKAVRENATLIELR 286
>BC121160-1|AAI21161.1| 462|Homo sapiens chromosome 14 open reading
frame 166B protein.
Length = 462
Score = 32.3 bits (70), Expect = 4.5
Identities = 16/39 (41%), Positives = 24/39 (61%), Gaps = 2/39 (5%)
Query: 45 INKCPNLQYLALTGNTLGVTAAHAISKALESHPELKIAR 83
+N+C L YL + GN +G A ISK LES+ L++ +
Sbjct: 274 LNRC--LVYLDIGGNDIGNEGASKISKGLESNESLRVLK 310
>BC121159-1|AAI21160.1| 462|Homo sapiens chromosome 14 open reading
frame 166B protein.
Length = 462
Score = 32.3 bits (70), Expect = 4.5
Identities = 16/39 (41%), Positives = 24/39 (61%), Gaps = 2/39 (5%)
Query: 45 INKCPNLQYLALTGNTLGVTAAHAISKALESHPELKIAR 83
+N+C L YL + GN +G A ISK LES+ L++ +
Sbjct: 274 LNRC--LVYLDIGGNDIGNEGASKISKGLESNESLRVLK 310
>AK027416-1|BAB55098.1| 753|Homo sapiens protein ( Homo sapiens
cDNA FLJ14510 fis, clone NT2RM1000623, weakly similar to
RIBONUCLEASE INHIBITOR. ).
Length = 753
Score = 32.3 bits (70), Expect = 4.5
Identities = 23/98 (23%), Positives = 40/98 (40%)
Query: 180 RNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTX 239
RN + + G L++ + SLEE+ + N I G+ L+ P L ++L+ N+
Sbjct: 474 RNSIGDVGCCHLSEALRAATSLEELDLSHNQIGDAGVQHLATILPGLPELRKIDLSGNSI 533
Query: 240 XXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAK 277
L + L+ + G L A LA+
Sbjct: 534 SSAGGVQLAESLVLCRRLEELMLGCNALGDPTALGLAQ 571
>AK027414-1|BAB55096.1| 753|Homo sapiens protein ( Homo sapiens
cDNA FLJ14508 fis, clone NT2RM1000421, weakly similar to
RIBONUCLEASE INHIBITOR. ).
Length = 753
Score = 32.3 bits (70), Expect = 4.5
Identities = 23/98 (23%), Positives = 40/98 (40%)
Query: 180 RNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLNDNTX 239
RN + + G L++ + SLEE+ + N I G+ L+ P L ++L+ N+
Sbjct: 474 RNSIGDVGCCHLSEALRAATSLEELDLSHNQIGDAGVQHLATILPGLPELRKIDLSGNSI 533
Query: 240 XXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAK 277
L + L+ + G L A LA+
Sbjct: 534 SSAGGVQLAESLVLCRRLEELMLGCNALGDPTALGLAQ 571
>AF111169-4|AAD44364.1| 608|Homo sapiens unknown protein.
Length = 608
Score = 32.3 bits (70), Expect = 4.5
Identities = 16/39 (41%), Positives = 24/39 (61%), Gaps = 2/39 (5%)
Query: 45 INKCPNLQYLALTGNTLGVTAAHAISKALESHPELKIAR 83
+N+C L YL + GN +G A ISK LES+ L++ +
Sbjct: 242 LNRC--LVYLDIGGNDIGNEGASKISKGLESNESLRVLK 278
>AB208891-1|BAD92128.1| 983|Homo sapiens Cryopyrin deletion 4
isoform variant protein.
Length = 983
Score = 32.3 bits (70), Expect = 4.5
Identities = 27/109 (24%), Positives = 49/109 (44%), Gaps = 6/109 (5%)
Query: 34 TAKDAQQIVDAINKCPNLQYLALTGNTLGVTAAHAISKALESHPELKIARFSDMFTGRMK 93
T+ + + ++ +L L L+ N+LG + + L+ HP I R ++ GR
Sbjct: 730 TSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQ-HPGCNIRR---LWLGRCG 785
Query: 94 TEIPPALSALGDGMIAAGARLAVLDLSDNAFGPIGVEGLAKLLQSDVCS 142
++++ +L LDLSDNA G G+ L L+ +C+
Sbjct: 786 LSHECCFDI--SLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCN 832
>BC020542-1|AAH20542.1| 352|Homo sapiens tropomodulin 3
(ubiquitous) protein.
Length = 352
Score = 31.9 bits (69), Expect = 5.9
Identities = 27/119 (22%), Positives = 46/119 (38%)
Query: 176 FIAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLN 235
F R + ATA A++ + +L+ + + N I VGI AL +A + N L L ++
Sbjct: 232 FSLAATRSNDPVATAFAEMLKVNKTLKSLNVESNFITGVGILALIDALRDNETLAELKID 291
Query: 236 DNTXXXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEVRNSLGN 294
+ +N + FG + A A N+ L+ R G+
Sbjct: 292 NQRQQLGTAVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLVRKRRVEGD 350
>BC017810-1|AAH17810.1| 345|Homo sapiens tropomodulin 4 (muscle)
protein.
Length = 345
Score = 31.9 bits (69), Expect = 5.9
Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 5/102 (4%)
Query: 191 LAKVFQEMGSLEEIAMPQNGIYHVGITALSE---AFKHNPALNHLNLNDNTXXXXXXXXX 247
L +V LEE+ + N I + I LSE A K N + +L
Sbjct: 187 LKRVRSNDKELEEVNL--NNIQDIPIPMLSELCEAMKANTYVRSFSLVATRSGDPIANAV 244
Query: 248 XXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEVR 289
L ++L+S+N + S G A+ KA + N+ L E+R
Sbjct: 245 ADMLRENRSLQSLNIESNFISSTGLMAVLKAVRENATLTELR 286
>AL592424-9|CAI16383.1| 345|Homo sapiens tropomodulin 4 (muscle)
protein.
Length = 345
Score = 31.9 bits (69), Expect = 5.9
Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 5/102 (4%)
Query: 191 LAKVFQEMGSLEEIAMPQNGIYHVGITALSE---AFKHNPALNHLNLNDNTXXXXXXXXX 247
L +V LEE+ + N I + I LSE A K N + +L
Sbjct: 187 LKRVRSNDKELEEVNL--NNIQDIPIPMLSELCEAMKANTYVRSFSLVATRSGDPIANAV 244
Query: 248 XXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEVR 289
L ++L+S+N + S G A+ KA + N+ L E+R
Sbjct: 245 ADMLRENRSLQSLNIESNFISSTGLMAVLKAVRENATLTELR 286
>AF393375-1|AAM73676.1| 345|Homo sapiens tropomodulin 4 protein.
Length = 345
Score = 31.9 bits (69), Expect = 5.9
Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 5/102 (4%)
Query: 191 LAKVFQEMGSLEEIAMPQNGIYHVGITALSE---AFKHNPALNHLNLNDNTXXXXXXXXX 247
L +V LEE+ + N I + I LSE A K N + +L
Sbjct: 187 LKRVRSNDKELEEVNL--NNIQDIPIPMLSELCEAMKANTYVRSFSLVATRSGDPIANAV 244
Query: 248 XXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEVR 289
L ++L+S+N + S G A+ KA + N+ L E+R
Sbjct: 245 ADMLRENRSLQSLNIESNFISSTGLMAVLKAVRENATLTELR 286
>AF321183-1|AAK06765.1| 345|Homo sapiens muscle tropomodulin
protein.
Length = 345
Score = 31.9 bits (69), Expect = 5.9
Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 5/102 (4%)
Query: 191 LAKVFQEMGSLEEIAMPQNGIYHVGITALSE---AFKHNPALNHLNLNDNTXXXXXXXXX 247
L +V LEE+ + N I + I LSE A K N + +L
Sbjct: 187 LKRVRSNDKELEEVNL--NNIQDIPIPMLSELCEAMKANTYVRSFSLVATRSGDPIANAV 244
Query: 248 XXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEVR 289
L ++L+S+N + S G A+ KA + N+ L E+R
Sbjct: 245 ADMLRENRSLQSLNIESNFISSTGLMAVLKAVRENATLTELR 286
>AF237631-1|AAF45299.1| 352|Homo sapiens ubiquitous tropomodulin
U-Tmod protein.
Length = 352
Score = 31.9 bits (69), Expect = 5.9
Identities = 27/119 (22%), Positives = 46/119 (38%)
Query: 176 FIAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLN 235
F R + ATA A++ + +L+ + + N I VGI AL +A + N L L ++
Sbjct: 232 FSLAATRSNDPVATAFAEMLKVNKTLKSLNVESNFITGVGILALIDALRDNETLAELKID 291
Query: 236 DNTXXXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEVRNSLGN 294
+ +N + FG + A A N+ L+ R G+
Sbjct: 292 NQRQQLGTAVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLVRKRRVEGD 350
>AF177173-1|AAF31672.1| 345|Homo sapiens tropomodulin 4 protein.
Length = 345
Score = 31.9 bits (69), Expect = 5.9
Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 5/102 (4%)
Query: 191 LAKVFQEMGSLEEIAMPQNGIYHVGITALSE---AFKHNPALNHLNLNDNTXXXXXXXXX 247
L +V LEE+ + N I + I LSE A K N + +L
Sbjct: 187 LKRVRSNDKELEEVNL--NNIQDIPIPMLSELCEAMKANTYVRSFSLVATRSGDPIANAV 244
Query: 248 XXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEVR 289
L ++L+S+N + S G A+ KA + N+ L E+R
Sbjct: 245 ADMLRENRSLQSLNIESNFISSTGLMAVLKAVRENATLTELR 286
>AF177171-1|AAF31670.1| 352|Homo sapiens tropomodulin 3 protein.
Length = 352
Score = 31.9 bits (69), Expect = 5.9
Identities = 27/119 (22%), Positives = 46/119 (38%)
Query: 176 FIAGRNRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNLN 235
F R + ATA A++ + +L+ + + N I VGI AL +A + N L L ++
Sbjct: 232 FSLAATRSNDPVATAFAEMLKVNKTLKSLNVESNFITGVGILALIDALRDNETLAELKID 291
Query: 236 DNTXXXXXXXXXXXXLPRLKNLKSINFGDCLLKSRGARALAKAFKGNSLLLEVRNSLGN 294
+ +N + FG + A A N+ L+ R G+
Sbjct: 292 NQRQQLGTAVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLVRKRRVEGD 350
>EF452237-1|ABO40480.1| 975|Homo sapiens NOD5 protein.
Length = 975
Score = 31.5 bits (68), Expect = 7.8
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 51 LQYLALTGNTLGVTAAHAISKALESHPELKIARFSDMFTGRMKTEIPPALSALGDGMIAA 110
LQ L + N G TAA A+++A HP L++ ++ + +E L LG G
Sbjct: 837 LQELNVAYNGAGDTAALALARAAREHPSLELLH---LYFNELSSEGRQVLRDLG-GAAEG 892
Query: 111 GARLAV 116
GAR+ V
Sbjct: 893 GARVVV 898
>BC110890-1|AAI10891.1| 975|Homo sapiens NLRX1 protein protein.
Length = 975
Score = 31.5 bits (68), Expect = 7.8
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 51 LQYLALTGNTLGVTAAHAISKALESHPELKIARFSDMFTGRMKTEIPPALSALGDGMIAA 110
LQ L + N G TAA A+++A HP L++ ++ + +E L LG G
Sbjct: 837 LQELNVAYNGAGDTAALALARAAREHPSLELLH---LYFNELSSEGRQVLRDLG-GAAEG 892
Query: 111 GARLAV 116
GAR+ V
Sbjct: 893 GARVVV 898
>AY245437-1|AAP31240.1| 975|Homo sapiens NOD26 protein.
Length = 975
Score = 31.5 bits (68), Expect = 7.8
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 51 LQYLALTGNTLGVTAAHAISKALESHPELKIARFSDMFTGRMKTEIPPALSALGDGMIAA 110
LQ L + N G TAA A+++A HP L++ ++ + +E L LG G
Sbjct: 837 LQELNVAYNGAGDTAALALARAAREHPSLELLH---LYFNELSSEGRQVLRDLG-GAAEG 892
Query: 111 GARLAV 116
GAR+ V
Sbjct: 893 GARVVV 898
>AK090431-1|BAC03412.1| 778|Homo sapiens FLJ00348 protein protein.
Length = 778
Score = 31.5 bits (68), Expect = 7.8
Identities = 19/54 (35%), Positives = 27/54 (50%)
Query: 181 NRLENDGATALAKVFQEMGSLEEIAMPQNGIYHVGITALSEAFKHNPALNHLNL 234
N++ N GA ALA+ SL + + N I G AL++A K N L L +
Sbjct: 693 NQISNKGAKALARSLLVNRSLTSLDLRGNSIGPQGAKALADALKINRTLTSLRV 746
>AK025131-1|BAB15075.1| 554|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21478 fis, clone COL05012. ).
Length = 554
Score = 31.5 bits (68), Expect = 7.8
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 51 LQYLALTGNTLGVTAAHAISKALESHPELKIARFSDMFTGRMKTEIPPALSALGDGMIAA 110
LQ L + N G TAA A+++A HP L++ ++ + +E L LG G
Sbjct: 416 LQELNVAYNGAGDTAALALARAAREHPSLELLH---LYFNELSSEGRQVLRDLG-GAAEG 471
Query: 111 GARLAV 116
GAR+ V
Sbjct: 472 GARVVV 477
>AB094095-1|BAC76049.1| 975|Homo sapiens DLNB26 protein.
Length = 975
Score = 31.5 bits (68), Expect = 7.8
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 51 LQYLALTGNTLGVTAAHAISKALESHPELKIARFSDMFTGRMKTEIPPALSALGDGMIAA 110
LQ L + N G TAA A+++A HP L++ ++ + +E L LG G
Sbjct: 837 LQELNVAYNGAGDTAALALARAAREHPSLELLH---LYFNELSSEGRQVLRDLG-GAAEG 892
Query: 111 GARLAV 116
GAR+ V
Sbjct: 893 GARVVV 898
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.317 0.134 0.384
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 58,942,793
Number of Sequences: 224733
Number of extensions: 1978360
Number of successful extensions: 4228
Number of sequences better than 10.0: 66
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 4008
Number of HSP's gapped (non-prelim): 255
length of query: 542
length of database: 73,234,838
effective HSP length: 94
effective length of query: 448
effective length of database: 52,109,936
effective search space: 23345251328
effective search space used: 23345251328
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 68 (31.5 bits)
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