Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001692-TA|BGIBMGA001692-PA|IPR002048|Calcium-binding
EF-hand, IPR011511|Variant SH3, IPR001452|Src homology-3,
IPR000108|Neutrophil cytosol factor 2, IPR000261|EPS15 homology (EH),
IPR010989|t-snare
(1304 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC116186-1|AAI16187.1| 1721|Homo sapiens intersectin 1 (SH3 doma... 179 5e-44
AF114488-1|AAD29953.1| 1220|Homo sapiens intersectin short isofo... 179 5e-44
AF114487-1|AAD29952.1| 1721|Homo sapiens intersectin long isofor... 179 5e-44
DQ679757-1|ABG74698.1| 1215|Homo sapiens intersectin 1 short for... 179 7e-44
DQ679756-1|ABG74697.1| 1178|Homo sapiens intersectin 1 short for... 179 7e-44
AF064244-1|AAC78611.1| 1721|Homo sapiens intersectin long form p... 179 7e-44
AF064243-1|AAC78610.1| 1220|Homo sapiens intersectin short form ... 179 7e-44
BC116185-1|AAI16186.1| 1716|Homo sapiens ITSN1 protein protein. 177 2e-43
U61166-1|AAC50592.1| 520|Homo sapiens SH3 domain-containing pro... 164 2e-39
BC117560-1|AAI17561.1| 1144|Homo sapiens ITSN1 protein protein. 164 2e-39
DQ679755-1|ABG74696.1| 1149|Homo sapiens intersectin 1 short for... 163 3e-39
DQ679754-1|ABG74695.1| 1144|Homo sapiens intersectin 1 short for... 163 3e-39
AF180522-1|AAD53183.1| 187|Homo sapiens intersectin short form ... 161 1e-38
AF248540-1|AAF63600.1| 1681|Homo sapiens intersectin 2 protein. 146 5e-34
AF182199-1|AAF59904.1| 1248|Homo sapiens intersectin 2 short iso... 146 5e-34
AF182198-1|AAF59903.1| 1696|Homo sapiens intersectin 2 long isof... 146 5e-34
AF001630-1|AAD00899.1| 464|Homo sapiens SH3P18-like WASP associ... 146 5e-34
AC009228-1|AAX93122.1| 1329|Homo sapiens unknown protein. 146 5e-34
AB033082-1|BAA86570.1| 1676|Homo sapiens KIAA1256 protein protein. 146 5e-34
DQ386455-1|ABD72328.1| 1020|Homo sapiens intersectin 1 short for... 134 3e-30
DQ340865-1|ABC69037.1| 1076|Homo sapiens intersectin 1 short for... 134 3e-30
BC073744-1|AAH73744.1| 648|Homo sapiens ITSN1 protein protein. 134 3e-30
BC058925-1|AAH58925.1| 634|Homo sapiens ITSN1 protein protein. 134 3e-30
BC039036-1|AAH39036.1| 345|Homo sapiens Similar to intersectin ... 134 3e-30
BC038963-1|AAH38963.1| 611|Homo sapiens Similar to intersectin ... 132 6e-30
BC020921-1|AAH20921.1| 560|Homo sapiens ITSN2 protein protein. 129 7e-29
BX538175-1|CAD98050.1| 627|Homo sapiens hypothetical protein pr... 123 4e-27
X17576-1|CAA35599.1| 377|Homo sapiens protein ( Human melanoma ... 108 1e-22
BC006403-1|AAH06403.1| 377|Homo sapiens NCK adaptor protein 1 p... 108 1e-22
AK021545-1|BAB13841.1| 436|Homo sapiens protein ( Homo sapiens ... 92 1e-17
BC007195-1|AAH07195.1| 380|Homo sapiens NCK adaptor protein 2 p... 89 7e-17
BC000103-1|AAH00103.1| 380|Homo sapiens NCK adaptor protein 2 p... 89 7e-17
AF047487-1|AAC80284.1| 380|Homo sapiens Nck-2 protein. 89 7e-17
AF043119-1|AAC04831.1| 381|Homo sapiens SH2/SH3 adaptor protein... 89 7e-17
AC009505-1|AAY24332.1| 304|Homo sapiens unknown protein. 89 7e-17
AY007161-1|AAG02009.1| 534|Homo sapiens protein ( Homo sapiens ... 87 3e-16
BC051823-1|AAH51823.1| 541|Homo sapiens EH-domain containing 4 ... 87 4e-16
BC006287-1|AAH06287.1| 541|Homo sapiens EH-domain containing 4 ... 87 4e-16
AF454953-1|AAL51079.1| 541|Homo sapiens EH domain-containing pr... 87 4e-16
AF323924-1|AAK11599.1| 541|Homo sapiens hepatocellular carcinom... 87 4e-16
AF181265-1|AAF40472.1| 482|Homo sapiens EH domain containing 4 ... 87 4e-16
BC104825-1|AAI04826.1| 534|Homo sapiens EH-domain containing 1 ... 86 7e-16
BC104799-1|AAI04800.1| 534|Homo sapiens EH-domain containing 1 ... 86 7e-16
AF001434-1|AAB81204.1| 534|Homo sapiens Hpast protein. 86 7e-16
AY340592-1|AAQ19991.1| 135|Homo sapiens intersectin 1 isoform 8... 85 2e-15
BC131590-1|AAI31591.1| 754|Homo sapiens EPS15L1 protein protein. 84 3e-15
AF110265-1|AAF21930.1| 864|Homo sapiens epidermal growth factor... 84 3e-15
AB015346-1|BAA88118.1| 864|Homo sapiens Eps15R protein. 84 3e-15
Z29064-1|CAA82305.1| 896|Homo sapiens AF-1p protein. 84 4e-15
U07707-1|AAA52101.1| 896|Homo sapiens epidermal growth factor r... 84 4e-15
DQ367924-1|ABD34786.1| 896|Homo sapiens epidermal growth factor... 84 4e-15
BC054006-1|AAH54006.1| 762|Homo sapiens EPS15 protein protein. 84 4e-15
AL671986-11|CAI13030.1| 896|Homo sapiens epidermal growth facto... 84 4e-15
AL671986-10|CAI13031.1| 762|Homo sapiens epidermal growth facto... 84 4e-15
AF214736-1|AAF32285.1| 535|Homo sapiens EH domain containing pr... 83 8e-15
AF181264-1|AAF40471.1| 546|Homo sapiens EH domain containing 3 ... 83 8e-15
AF099011-1|AAD45866.1| 534|Homo sapiens EH-domain containing pr... 83 8e-15
BC014445-1|AAH14445.1| 543|Homo sapiens EH-domain containing 2 ... 79 8e-14
AF454952-1|AAL51078.1| 543|Homo sapiens EH domain-containing pr... 79 8e-14
AF181263-1|AAF40470.1| 543|Homo sapiens EH domain containing 2 ... 79 8e-14
BC108893-1|AAI08894.1| 728|Homo sapiens SH3D19 protein protein. 76 1e-12
BC108892-1|AAI08893.1| 764|Homo sapiens SH3D19 protein protein. 76 1e-12
BC108891-1|AAI08892.1| 764|Homo sapiens SH3D19 protein protein. 76 1e-12
BC108890-1|AAI08891.1| 764|Homo sapiens SH3D19 protein protein. 76 1e-12
BC085613-1|AAH85613.1| 420|Homo sapiens SH3D19 protein protein. 76 1e-12
BC045742-1|AAH45742.1| 208|Homo sapiens SH3D19 protein protein. 76 1e-12
AL133047-1|CAB61374.1| 408|Homo sapiens hypothetical protein pr... 76 1e-12
AL591845-2|CAH71860.2| 378|Homo sapiens chromosome 1 open readi... 73 9e-12
BC011883-1|AAH11883.1| 645|Homo sapiens SORBS2 protein protein. 69 8e-11
AF049884-1|AAC05508.1| 666|Homo sapiens Arg/Abl-interacting pro... 69 8e-11
AB018320-1|BAA34497.2| 1171|Homo sapiens KIAA0777 protein protein. 69 8e-11
BC050663-1|AAH50663.1| 381|Homo sapiens SH3KBP1 protein protein. 69 1e-10
BC015806-1|AAH15806.1| 665|Homo sapiens SH3-domain kinase bindi... 69 1e-10
AY542305-1|AAT08174.1| 665|Homo sapiens GIG10 protein. 69 1e-10
AY423734-1|AAS00497.1| 665|Homo sapiens migration-inducing gene... 69 1e-10
AL772197-2|CAH71710.1| 665|Homo sapiens SH3-domain kinase bindi... 69 1e-10
AL772197-1|CAH71709.1| 553|Homo sapiens SH3-domain kinase bindi... 69 1e-10
AL732423-3|CAI40276.1| 665|Homo sapiens SH3-domain kinase bindi... 69 1e-10
AL732327-2|CAI40510.1| 665|Homo sapiens SH3-domain kinase bindi... 69 1e-10
AL732327-1|CAI40509.1| 553|Homo sapiens SH3-domain kinase bindi... 69 1e-10
AL732325-2|CAI41253.1| 665|Homo sapiens SH3-domain kinase bindi... 69 1e-10
AL732325-1|CAI41252.1| 553|Homo sapiens SH3-domain kinase bindi... 69 1e-10
AF230904-1|AAF37854.1| 665|Homo sapiens c-Cbl-interacting prote... 69 1e-10
BC021211-1|AAH21211.1| 653|Homo sapiens REPS1 protein protein. 69 1e-10
BC012764-1|AAH12764.1| 743|Homo sapiens RALBP1 associated Eps d... 69 1e-10
AL121834-13|CAI42879.1| 743|Homo sapiens RALBP1 associated Eps ... 69 1e-10
AL121834-12|CAI42877.1| 744|Homo sapiens RALBP1 associated Eps ... 69 1e-10
AL121834-11|CAI42878.1| 653|Homo sapiens RALBP1 associated Eps ... 69 1e-10
AF251052-1|AAK34942.1| 744|Homo sapiens RALBP1 protein. 69 1e-10
U14391-1|AAA62667.1| 1109|Homo sapiens myosin-IC protein. 66 8e-10
BC098392-1|AAH98392.1| 1108|Homo sapiens myosin IE protein. 66 8e-10
BC010110-1|AAH10110.1| 267|Homo sapiens DKFZp434D0215 protein p... 66 8e-10
BC065731-1|AAH65731.1| 390|Homo sapiens neutrophil cytosolic fa... 66 1e-09
BC002816-1|AAH02816.1| 390|Homo sapiens neutrophil cytosolic fa... 66 1e-09
AY358478-1|AAQ88842.1| 370|Homo sapiens QLAK737 protein. 66 1e-09
AY217346-1|AAO45099.1| 690|Homo sapiens FLJ00007-like protein p... 66 1e-09
AK223217-1|BAD96937.1| 390|Homo sapiens neutrophil cytosolic fa... 66 1e-09
AK000007-1|BAA92232.1| 701|Homo sapiens FLJ00007 protein protein. 66 1e-09
AC083884-6|AAS07465.1| 390|Homo sapiens unknown protein. 66 1e-09
U57835-1|AAB95193.1| 390|Homo sapiens p47-phox protein. 65 1e-09
M55067-1|AAA59901.1| 390|Homo sapiens autosomal chronic granulo... 65 1e-09
M25665-1|AAA57209.1| 390|Homo sapiens neutrophil cytosol factor... 65 1e-09
DQ314878-1|ABC40737.1| 258|Homo sapiens neutrophil cytosolic fa... 65 1e-09
AF330627-1|AAK19518.1| 390|Homo sapiens adaptor protein p47phox... 65 1e-09
AF184614-1|AAF34737.1| 390|Homo sapiens p47-phox protein. 65 1e-09
AL929302-8|CAI41286.1| 659|Homo sapiens RALBP1 associated Eps d... 65 2e-09
AL732371-2|CAI40017.1| 659|Homo sapiens RALBP1 associated Eps d... 65 2e-09
AF512951-1|AAM43953.1| 520|Homo sapiens RALBP1 associated Eps d... 65 2e-09
AF511533-1|AAM43933.1| 659|Homo sapiens RALBP1 associated Eps d... 65 2e-09
AF010233-1|AAC02901.1| 521|Homo sapiens RalBP1-interacting prot... 65 2e-09
AB208937-1|BAD92174.1| 514|Homo sapiens RalBP1 associated Eps d... 65 2e-09
AF330626-1|AAK19517.1| 254|Homo sapiens adaptor protein p47phox... 64 2e-09
AF330625-1|AAK19516.1| 276|Homo sapiens adaptor protein p47phox... 64 4e-09
AF049885-1|AAC05509.1| 640|Homo sapiens Arg/Abl-interacting pro... 63 7e-09
BC091514-1|AAH91514.1| 671|Homo sapiens sorbin and SH3 domain c... 62 1e-08
BC067260-1|AAH67260.2| 671|Homo sapiens sorbin and SH3 domain c... 62 1e-08
BC017751-1|AAH17751.1| 330|Homo sapiens FCHSD2 protein protein. 62 1e-08
BC010146-1|AAH10146.1| 329|Homo sapiens sorbin and SH3 domain c... 62 1e-08
AF064807-1|AAD32304.1| 329|Homo sapiens vinexin beta protein. 62 1e-08
AF037261-1|AAC09244.1| 671|Homo sapiens SH3-containing adaptor ... 62 1e-08
AB018312-1|BAA34489.2| 746|Homo sapiens KIAA0769 protein protein. 62 1e-08
X95677-1|CAA64980.1| 299|Homo sapiens argBPIB protein. 61 3e-08
X95632-1|CAA64885.1| 475|Homo sapiens Arg protein tyrosine kina... 61 3e-08
U23435-1|AAA92289.1| 401|Homo sapiens Abl interactor 2 protein. 61 3e-08
BT009920-1|AAP88922.1| 475|Homo sapiens abl-interactor 2 protein. 61 3e-08
BC001439-1|AAH01439.1| 475|Homo sapiens abl interactor 2 protein. 61 3e-08
AF260261-1|AAF70308.1| 513|Homo sapiens Abl-interactor protein ... 61 3e-08
AC018891-1|AAY14675.1| 321|Homo sapiens unknown protein. 61 3e-08
AL133355-1|CAI15351.1| 1059|Homo sapiens SH3 and PX domains 2A p... 60 4e-08
AL121929-4|CAI13961.1| 1059|Homo sapiens SH3 and PX domains 2A p... 60 4e-08
AB007878-1|BAA24848.2| 989|Homo sapiens KIAA0418 protein. 60 4e-08
AL121929-6|CAI13963.1| 940|Homo sapiens SH3 and PX domains 2A p... 60 5e-08
U07747-1|AAA19647.1| 847|Homo sapiens serine/threonine protein ... 59 1e-07
L32976-1|AAA59859.1| 847|Homo sapiens protein kinase protein. 59 1e-07
BC064543-1|AAH64543.1| 847|Homo sapiens mitogen-activated prote... 59 1e-07
BC011263-1|AAH11263.1| 847|Homo sapiens mitogen-activated prote... 59 1e-07
AL121834-10|CAI42876.1| 279|Homo sapiens RALBP1 associated Eps ... 59 1e-07
AK222781-1|BAD96501.1| 847|Homo sapiens mitogen-activated prote... 59 1e-07
AB209655-1|BAD92892.1| 310|Homo sapiens mitogen-activated prote... 59 1e-07
X98411-1|CAA67058.1| 782|Homo sapiens myosin-IF protein. 58 2e-07
CR457361-1|CAG33642.1| 323|Homo sapiens SH3YL1 protein. 58 2e-07
BC028071-1|AAH28071.1| 1098|Homo sapiens myosin IF protein. 58 2e-07
BC008375-1|AAH08375.1| 323|Homo sapiens SH3YL1 protein protein. 58 2e-07
BC008374-1|AAH08374.1| 342|Homo sapiens SH3YL1 protein protein. 58 2e-07
AL732423-6|CAI40280.1| 645|Homo sapiens SH3-domain kinase bindi... 58 2e-07
AL732423-4|CAI40277.1| 628|Homo sapiens SH3-domain kinase bindi... 58 2e-07
AL732327-6|CAI40514.1| 645|Homo sapiens SH3-domain kinase bindi... 58 2e-07
AL732327-3|CAI40511.1| 628|Homo sapiens SH3-domain kinase bindi... 58 2e-07
AL732325-3|CAI41254.1| 628|Homo sapiens SH3-domain kinase bindi... 58 2e-07
AK026507-1|BAB15493.1| 323|Homo sapiens protein ( Homo sapiens ... 58 2e-07
AJ310570-1|CAC83948.1| 1098|Homo sapiens Myosin-1F protein. 58 2e-07
AF542051-1|AAN77231.1| 628|Homo sapiens CD2 binding protein CD2... 58 2e-07
AC079779-1|AAY14957.1| 342|Homo sapiens unknown protein. 58 2e-07
AB210037-1|BAE06119.1| 1143|Homo sapiens MYO1F variant protein p... 58 2e-07
X16663-1|CAA34651.1| 486|Homo sapiens protein ( Human HS1 gene ... 58 2e-07
U43899-1|AAC50734.1| 540|Homo sapiens STAM protein. 58 2e-07
DQ307286-1|ABC25188.1| 269|Homo sapiens plenty of SH3s-2 protein. 58 2e-07
CR456794-1|CAG33075.1| 486|Homo sapiens HCLS1 protein. 58 2e-07
BT006824-1|AAP35470.1| 486|Homo sapiens hematopoietic cell-spec... 58 2e-07
BC109231-1|AAI09232.1| 269|Homo sapiens STAC2 protein protein. 58 2e-07
BC030586-1|AAH30586.1| 403|Homo sapiens STAM protein protein. 58 2e-07
BC016758-1|AAH16758.1| 486|Homo sapiens hematopoietic cell-spec... 58 2e-07
AK131500-1|BAD18644.1| 411|Homo sapiens protein ( Homo sapiens ... 58 2e-07
AJ608762-1|CAE75539.1| 411|Homo sapiens 24b2/STAC2 protein prot... 58 2e-07
U31089-1|AAA75446.1| 390|Homo sapiens Abl binding protein 3 pro... 58 3e-07
AL732423-5|CAI40278.1| 427|Homo sapiens SH3-domain kinase bindi... 58 3e-07
AL732327-4|CAI40512.1| 427|Homo sapiens SH3-domain kinase bindi... 58 3e-07
U63717-1|AAB06396.1| 214|Homo sapiens osteoclast stimulating fa... 57 4e-07
M98343-1|AAA58455.1| 550|Homo sapiens amplaxin protein. 57 4e-07
M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein. 57 4e-07
M16038-1|AAA59540.1| 512|Homo sapiens LYN protein. 57 4e-07
D25304-1|BAA04985.1| 773|Homo sapiens KIAA0006 protein. 57 4e-07
DQ109556-1|AAZ99795.1| 911|Homo sapiens adaptor protein HOFI pr... 57 4e-07
BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein. 57 4e-07
BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein. 57 4e-07
BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 57 4e-07
BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 57 4e-07
BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein. 57 4e-07
BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein. 57 4e-07
BC043505-1|AAH43505.1| 538|Homo sapiens ARHGEF6 protein protein. 57 4e-07
BC039856-1|AAH39856.1| 776|Homo sapiens Rac/Cdc42 guanine nucle... 57 4e-07
BC008799-1|AAH08799.1| 513|Homo sapiens cortactin protein. 57 4e-07
BC007459-1|AAH07459.1| 217|Homo sapiens OSTF1 protein protein. 57 4e-07
AL683813-1|CAI39443.1| 776|Homo sapiens Rac/Cdc42 guanine nucle... 57 4e-07
AL135783-5|CAI42903.1| 622|Homo sapiens Rac/Cdc42 guanine nucle... 57 4e-07
AL135783-1|CAI42899.1| 776|Homo sapiens Rac/Cdc42 guanine nucle... 57 4e-07
AL133548-4|CAH71573.1| 214|Homo sapiens osteoclast stimulating ... 57 4e-07
AK222613-1|BAD96333.1| 550|Homo sapiens cortactin isoform a var... 57 4e-07
AK222596-1|BAD96316.1| 214|Homo sapiens osteoclast stimulating ... 57 4e-07
D63476-1|BAA09763.2| 802|Homo sapiens KIAA0142 protein. 56 6e-07
BC060776-1|AAH60776.1| 803|Homo sapiens ARHGEF7 protein protein. 56 6e-07
BC050521-1|AAH50521.1| 764|Homo sapiens Rho guanine nucleotide ... 56 6e-07
BC033905-1|AAH33905.1| 753|Homo sapiens ARHGEF7 protein protein. 56 6e-07
AL834228-1|CAD38906.1| 812|Homo sapiens hypothetical protein pr... 56 6e-07
AF329268-1|AAO13348.1| 404|Homo sapiens SH3-domain kinase bindi... 56 6e-07
AF329267-1|AAK95587.1| 404|Homo sapiens SH3-domain kinase bindi... 56 6e-07
AB177848-1|BAD66826.1| 691|Homo sapiens KIAA0142 splice variant... 56 6e-07
BC053671-1|AAH53671.1| 1056|Homo sapiens SH3RF1 protein protein. 56 8e-07
BC041023-1|AAH41023.1| 302|Homo sapiens SH3RF1 protein protein. 56 8e-07
AL390754-5|CAM13628.1| 646|Homo sapiens Rho guanine nucleotide ... 56 8e-07
AL390754-4|CAI12463.1| 705|Homo sapiens Rho guanine nucleotide ... 56 8e-07
AL390754-3|CAI12462.1| 66|Homo sapiens Rho guanine nucleotide ... 56 8e-07
AL390754-2|CAI12461.1| 625|Homo sapiens Rho guanine nucleotide ... 56 8e-07
AL390754-1|CAI12460.1| 123|Homo sapiens Rho guanine nucleotide ... 56 8e-07
AL139086-4|CAM20788.1| 646|Homo sapiens Rho guanine nucleotide ... 56 8e-07
AL139086-3|CAI14672.1| 705|Homo sapiens Rho guanine nucleotide ... 56 8e-07
AL139086-2|CAI14671.1| 625|Homo sapiens Rho guanine nucleotide ... 56 8e-07
AL139086-1|CAI14670.1| 123|Homo sapiens Rho guanine nucleotide ... 56 8e-07
AK021429-1|BAB13822.1| 712|Homo sapiens protein ( Homo sapiens ... 56 8e-07
AB177849-1|BAD66827.1| 680|Homo sapiens KIAA0142 splice variant... 56 8e-07
Y10388-1|CAA71414.2| 759|Homo sapiens Graf protein protein. 56 1e-06
BC068555-1|AAH68555.1| 759|Homo sapiens ARHGAP26 protein protein. 56 1e-06
BC028740-1|AAH28740.1| 525|Homo sapiens signal transducing adap... 56 1e-06
AF042274-1|AAC63964.1| 342|Homo sapiens signal transducing adap... 56 1e-06
AF042273-1|AAC63963.1| 525|Homo sapiens signal transducing adap... 56 1e-06
AC079790-2|AAY14712.1| 525|Homo sapiens unknown protein. 56 1e-06
Z82206-3|CAI42713.1| 330|Homo sapiens GRB2-related adaptor prot... 55 1e-06
Y18051-1|CAA77021.1| 330|Homo sapiens GADS protein protein. 55 1e-06
X62852-1|CAA44664.1| 160|Homo sapiens ash protein protein. 55 1e-06
U87166-1|AAC39757.1| 508|Homo sapiens spectrin SH3 domain bindi... 55 1e-06
M96995-1|AAA58448.1| 217|Homo sapiens epidermal growth factor r... 55 1e-06
L29511-1|AAC37549.1| 176|Homo sapiens growth factor receptor-bo... 55 1e-06
CR541942-1|CAG46740.1| 217|Homo sapiens GRB2 protein. 55 1e-06
CR541849-1|CAG46647.1| 330|Homo sapiens GRAP2 protein. 55 1e-06
CR536524-1|CAG38761.1| 330|Homo sapiens GRAP2 protein. 55 1e-06
CR456498-1|CAG30384.1| 330|Homo sapiens GRAP2 protein. 55 1e-06
BC125107-1|AAI25108.1| 729|Homo sapiens SH3 domain containing r... 55 1e-06
BC125106-1|AAI25107.1| 729|Homo sapiens SH3 domain containing r... 55 1e-06
BC032468-1|AAH32468.1| 104|Homo sapiens DKFZp434D0215 protein p... 55 1e-06
BC026002-1|AAH26002.1| 330|Homo sapiens GRAP2 protein protein. 55 1e-06
BC025692-1|AAH25692.1| 330|Homo sapiens GRB2-related adaptor pr... 55 1e-06
BC024254-1|AAH24254.1| 476|Homo sapiens abl-interactor 1 protein. 55 1e-06
BC000631-1|AAH00631.1| 217|Homo sapiens growth factor receptor-... 55 1e-06
AY196211-1|AAP34307.1| 1577|Homo sapiens TUBA protein. 55 1e-06
AY069959-1|AAL58573.1| 330|Homo sapiens Mona protein. 55 1e-06
AL627434-2|CAI13197.1| 1601|Homo sapiens novel protein protein. 55 1e-06
AL441886-1|CAI13076.1| 1601|Homo sapiens novel protein protein. 55 1e-06
AL392107-2|CAI11009.1| 1601|Homo sapiens novel protein protein. 55 1e-06
AL390961-8|CAI17274.1| 476|Homo sapiens spectrin SH3 domain bin... 55 1e-06
AL390961-7|CAI17277.1| 480|Homo sapiens spectrin SH3 domain bin... 55 1e-06
AL390961-6|CAI17276.1| 481|Homo sapiens spectrin SH3 domain bin... 55 1e-06
AL390961-5|CAI17275.1| 508|Homo sapiens spectrin SH3 domain bin... 55 1e-06
AL390961-4|CAI17273.1| 475|Homo sapiens spectrin SH3 domain bin... 55 1e-06
AL390961-3|CAI17272.1| 446|Homo sapiens spectrin SH3 domain bin... 55 1e-06
AL390961-2|CAI17279.1| 451|Homo sapiens spectrin SH3 domain bin... 55 1e-06
AL390961-1|CAI17278.1| 452|Homo sapiens spectrin SH3 domain bin... 55 1e-06
AL139404-8|CAH73116.1| 452|Homo sapiens spectrin SH3 domain bin... 55 1e-06
AL139404-7|CAH73115.1| 476|Homo sapiens spectrin SH3 domain bin... 55 1e-06
AL139404-6|CAH73114.1| 480|Homo sapiens spectrin SH3 domain bin... 55 1e-06
AL139404-5|CAH73113.1| 481|Homo sapiens spectrin SH3 domain bin... 55 1e-06
AL139404-4|CAH73112.1| 508|Homo sapiens spectrin SH3 domain bin... 55 1e-06
AL139404-3|CAH73119.1| 475|Homo sapiens spectrin SH3 domain bin... 55 1e-06
AL139404-2|CAH73118.1| 446|Homo sapiens spectrin SH3 domain bin... 55 1e-06
AL139404-1|CAH73117.1| 451|Homo sapiens spectrin SH3 domain bin... 55 1e-06
AJ277065-1|CAB88006.1| 508|Homo sapiens spectrin SH3 binding pr... 55 1e-06
AJ011736-1|CAA09757.1| 330|Homo sapiens growth factor receptor ... 55 1e-06
AF540955-1|AAN28379.1| 476|Homo sapiens Abl-interactor 1 protein. 55 1e-06
AF498925-1|AAM21073.1| 217|Homo sapiens growth factor receptor-... 55 1e-06
AF260262-1|AAF70309.1| 446|Homo sapiens Abl-interactor protein ... 55 1e-06
AF236120-1|AAF60320.1| 330|Homo sapiens adapter protein GRID pr... 55 1e-06
AF129476-1|AAD41782.1| 330|Homo sapiens hematopoietic cell-asso... 55 1e-06
AF121002-1|AAF31758.1| 330|Homo sapiens SH3-SH2-SH3 adaptor pro... 55 1e-06
AF102694-1|AAD04926.1| 330|Homo sapiens Grb2-related adaptor pr... 55 1e-06
AF090456-1|AAD13027.1| 330|Homo sapiens Grb-2-like protein prot... 55 1e-06
AF063618-1|AAC72075.1| 217|Homo sapiens growth factor receptor-... 55 1e-06
AF042380-1|AAC69273.1| 330|Homo sapiens Grf40 adaptor protein p... 55 1e-06
AF006516-1|AAB62569.1| 480|Homo sapiens e3B1 protein. 55 1e-06
AF001628-1|AAD00897.1| 451|Homo sapiens interactor protein AblB... 55 1e-06
AB209268-1|BAD92505.1| 476|Homo sapiens Abl-interactor 1 varian... 55 1e-06
AB040151-1|BAB55675.1| 452|Homo sapiens hNap1 Binding Protein p... 55 1e-06
DQ297143-1|ABB84466.1| 1291|Homo sapiens phospholipase C, gamma ... 55 2e-06
AB210028-1|BAE06110.1| 1412|Homo sapiens PLCG1 variant protein p... 55 2e-06
Z68128-1|CAA92213.1| 946|Homo sapiens C1 protein. 54 3e-06
X78817-1|CAA55394.1| 946|Homo sapiens p115 protein. 54 3e-06
D50921-1|BAA09480.1| 942|Homo sapiens KIAA0131 protein. 54 3e-06
BC052303-1|AAH52303.1| 986|Homo sapiens ARHGAP4 protein protein. 54 3e-06
BC023626-1|AAH23626.1| 356|Homo sapiens ARHGAP4 protein protein. 54 3e-06
BC007780-1|AAH07780.1| 366|Homo sapiens ABI gene family, member... 54 3e-06
AB037886-1|BAA90667.1| 366|Homo sapiens NESH protein. 54 3e-06
M34667-1|AAA36452.1| 1290|Homo sapiens protein ( Human phospholi... 54 3e-06
AL022394-3|CAA18537.1| 1290|Homo sapiens phospholipase C, gamma ... 54 3e-06
AL022394-2|CAM28260.1| 1291|Homo sapiens phospholipase C, gamma ... 54 3e-06
U52518-1|AAC50541.1| 217|Homo sapiens Grb2-related adaptor prot... 54 4e-06
CR541966-1|CAG46764.1| 217|Homo sapiens GRAP protein. 54 4e-06
CR541941-1|CAG46739.1| 217|Homo sapiens GRAP protein. 54 4e-06
BT019981-1|AAV38784.1| 217|Homo sapiens GRB2-related adaptor pr... 54 4e-06
BC069444-1|AAH69444.1| 639|Homo sapiens CD2-associated protein ... 54 4e-06
BC063035-1|AAH63035.1| 217|Homo sapiens GRB2-related adaptor pr... 54 4e-06
BC035856-1|AAH35856.1| 217|Homo sapiens GRB2-related adaptor pr... 54 4e-06
AL358178-2|CAI16839.1| 639|Homo sapiens CD2-associated protein ... 54 4e-06
AL355353-1|CAH73238.1| 639|Homo sapiens CD2-associated protein ... 54 4e-06
AF236119-1|AAF60319.1| 330|Homo sapiens adapter protein GRID pr... 54 4e-06
AF164377-1|AAF80495.1| 639|Homo sapiens CD2AP homolog protein. 54 4e-06
AF146277-1|AAD34595.1| 639|Homo sapiens adapter protein CMS pro... 54 4e-06
X83931-1|CAA58783.1| 539|Homo sapiens VAV protein. 53 6e-06
X16316-1|CAA34383.1| 797|Homo sapiens VAV protein. 53 6e-06
BC013361-1|AAH13361.2| 790|Homo sapiens VAV1 protein protein. 53 6e-06
AF030227-1|AAC25011.1| 845|Homo sapiens vav protein protein. 53 6e-06
S76992-1|AAB34377.1| 878|Homo sapiens VAV2 protein. 53 8e-06
BX640754-1|CAE45861.1| 801|Homo sapiens hypothetical protein pr... 53 8e-06
BC132967-1|AAI32968.1| 839|Homo sapiens vav 2 oncogene protein. 53 8e-06
BC132965-1|AAI32966.1| 839|Homo sapiens vav 2 oncogene protein. 53 8e-06
BC128448-1|AAI28449.1| 474|Homo sapiens VAV2 protein protein. 53 8e-06
BC033187-1|AAH33187.1| 369|Homo sapiens VAV2 protein protein. 53 8e-06
AY254341-1|AAP13099.1| 102|Homo sapiens intersectin 1 isoform 5... 53 8e-06
AL590710-7|CAI12279.1| 878|Homo sapiens vav 2 oncogene protein. 53 8e-06
AL590710-6|CAI12278.1| 868|Homo sapiens vav 2 oncogene protein. 53 8e-06
AL590710-5|CAI12280.1| 839|Homo sapiens vav 2 oncogene protein. 53 8e-06
AL445931-3|CAI13723.1| 868|Homo sapiens vav 2 oncogene protein. 53 8e-06
AL445931-2|CAI13722.1| 878|Homo sapiens vav 2 oncogene protein. 53 8e-06
AL445931-1|CAI13724.1| 839|Homo sapiens vav 2 oncogene protein. 53 8e-06
AL357934-3|CAI15781.1| 868|Homo sapiens vav 2 oncogene protein. 53 8e-06
AL357934-2|CAI15783.1| 878|Homo sapiens vav 2 oncogene protein. 53 8e-06
AL357934-1|CAI15782.1| 839|Homo sapiens vav 2 oncogene protein. 53 8e-06
CR450363-1|CAG29359.1| 217|Homo sapiens GRB2 protein. 52 1e-05
BX640814-1|CAE45892.1| 548|Homo sapiens hypothetical protein pr... 52 1e-05
AM260536-1|CAJ97431.1| 1266|Homo sapiens ponsin protein. 52 1e-05
AL158165-9|CAI14378.1| 816|Homo sapiens sorbin and SH3 domain c... 52 1e-05
AL158165-8|CAI14382.1| 781|Homo sapiens sorbin and SH3 domain c... 52 1e-05
AL158165-7|CAI14380.1| 811|Homo sapiens sorbin and SH3 domain c... 52 1e-05
AL158165-6|CAI14385.1| 1004|Homo sapiens sorbin and SH3 domain c... 52 1e-05
AL158165-5|CAI14384.1| 684|Homo sapiens sorbin and SH3 domain c... 52 1e-05
AL158165-4|CAI14383.1| 905|Homo sapiens sorbin and SH3 domain c... 52 1e-05
AL158165-3|CAI14381.1| 1151|Homo sapiens sorbin and SH3 domain c... 52 1e-05
AL158165-2|CAI14379.1| 1292|Homo sapiens sorbin and SH3 domain c... 52 1e-05
AJ489942-1|CAD34588.1| 846|Homo sapiens c-Cbl associated protei... 52 1e-05
AF356527-1|AAK37565.1| 905|Homo sapiens sorbin and SH3 domain c... 52 1e-05
AF356526-1|AAK37564.1| 1151|Homo sapiens sorbin and SH3 domain c... 52 1e-05
AF356525-1|AAK37563.1| 1292|Homo sapiens sorbin and SH3 domain c... 52 1e-05
AF330624-1|AAK57480.1| 377|Homo sapiens retina R85 protein. 52 1e-05
AF330623-1|AAK57479.1| 811|Homo sapiens brain R85FL protein. 52 1e-05
AF136381-1|AAF22175.1| 1004|Homo sapiens c-Cbl-associated protei... 52 1e-05
AF136380-1|AAD27647.1| 684|Homo sapiens SH3P12 protein protein. 52 1e-05
AB037717-1|BAA92534.1| 815|Homo sapiens KIAA1296 protein protein. 52 1e-05
Z33998-1|CAA83965.1| 505|Homo sapiens Protein-Tyrosine Kinase p... 52 1e-05
S76617-1|AAB33265.1| 505|Homo sapiens blk protein. 52 1e-05
CR457328-1|CAG33609.1| 219|Homo sapiens FLJ20896 protein. 52 1e-05
BC128055-1|AAI28056.1| 786|Homo sapiens Rho GTPase activating p... 52 1e-05
BC109030-1|AAI09031.1| 782|Homo sapiens ARHGAP10 protein protein. 52 1e-05
BC106018-1|AAI06019.1| 232|Homo sapiens ARHGAP10 protein protein. 52 1e-05
BC047914-1|AAH47914.1| 367|Homo sapiens ARHGAP10 protein protein. 52 1e-05
BC032413-1|AAH32413.1| 505|Homo sapiens B lymphoid tyrosine kin... 52 1e-05
BC018703-1|AAH18703.1| 599|Homo sapiens Unknown (protein for IM... 52 1e-05
BC011920-1|AAH11920.2| 629|Homo sapiens ARHGAP10 protein protein. 52 1e-05
BC007371-1|AAH07371.1| 505|Homo sapiens B lymphoid tyrosine kin... 52 1e-05
AL834360-1|CAD39024.1| 333|Homo sapiens hypothetical protein pr... 52 1e-05
AK024549-1|BAB14924.1| 219|Homo sapiens protein ( Homo sapiens ... 52 1e-05
BC126899-1|AAI26900.1| 785|Homo sapiens ARHGAP10 protein protein. 52 2e-05
BC109029-1|AAI09030.1| 782|Homo sapiens ARHGAP10 protein protein. 52 2e-05
AL591042-2|CAI14458.1| 753|Homo sapiens vav 3 oncogene protein. 52 2e-05
AL591042-1|CAI14457.1| 847|Homo sapiens vav 3 oncogene protein. 52 2e-05
AL513206-2|CAH73196.1| 753|Homo sapiens vav 3 oncogene protein. 52 2e-05
AL513206-1|CAH73195.1| 847|Homo sapiens vav 3 oncogene protein. 52 2e-05
AL391235-1|CAH72458.1| 847|Homo sapiens vav 3 oncogene protein. 52 2e-05
AL353892-1|CAI21786.1| 847|Homo sapiens vav 3 oncogene protein. 52 2e-05
AF118887-1|AAD20349.1| 847|Homo sapiens VAV-3 protein protein. 52 2e-05
AF118886-1|AAD20348.1| 753|Homo sapiens VAV-3 protein beta isof... 52 2e-05
AF067817-1|AAC79695.1| 847|Homo sapiens VAV-3 protein protein. 52 2e-05
DQ402497-1|ABD62889.1| 478|Homo sapiens nostrin protein. 51 3e-05
BC093072-1|AAH93072.1| 506|Homo sapiens nitric oxide synthase t... 51 3e-05
BC014189-1|AAH14189.1| 428|Homo sapiens nitric oxide synthase t... 51 3e-05
BC011889-1|AAH11889.1| 424|Homo sapiens protein kinase C and ca... 51 3e-05
BC008602-1|AAH08602.1| 416|Homo sapiens proline-serine-threonin... 51 3e-05
BC008069-1|AAH08069.1| 325|Homo sapiens STAC3 protein protein. 51 3e-05
BC007914-1|AAH07914.1| 424|Homo sapiens protein kinase C and ca... 51 3e-05
AL121834-9|CAI42875.1| 189|Homo sapiens RALBP1 associated Eps d... 51 3e-05
AK057013-1|BAB71343.1| 364|Homo sapiens protein ( Homo sapiens ... 51 3e-05
AK002203-1|BAE46614.1| 506|Homo sapiens protein ( Homo sapiens ... 51 3e-05
AJ532842-1|CAD58724.1| 506|Homo sapiens NOSTRIN protein protein. 51 3e-05
AF242530-1|AAK29207.1| 424|Homo sapiens protein kinase C and ca... 51 3e-05
AF149825-1|AAG31023.1| 424|Homo sapiens PACSIN3 protein. 51 3e-05
AF130979-1|AAF04472.1| 424|Homo sapiens SH3 domain-containing p... 51 3e-05
AF038603-1|AAD11959.1| 416|Homo sapiens CD2 binding protein 1 l... 51 3e-05
AF038602-1|AAD11958.1| 397|Homo sapiens CD2 binding protein 1 s... 51 3e-05
AB051470-1|BAB21774.1| 832|Homo sapiens KIAA1683 protein protein. 51 3e-05
DQ090887-1|AAY99645.1| 1196|Homo sapiens AHI1 protein. 50 4e-05
BC133706-1|AAI33707.1| 1104|Homo sapiens MAP3K9 protein protein. 50 4e-05
BC111407-1|AAI11408.1| 1103|Homo sapiens MAP3K9 protein protein. 50 4e-05
AY327900-1|AAQ23054.1| 1104|Homo sapiens mixed-lineage protein k... 50 4e-05
AL133544-3|CAI22523.1| 1168|Homo sapiens protein ( Human DNA seq... 50 4e-05
AL049552-2|CAI20387.1| 1168|Homo sapiens protein ( EB-RP (G13), ... 50 4e-05
AL023693-5|CAI20201.1| 1168|Homo sapiens protein ( Human DNA seq... 50 4e-05
AK092262-1|BAC03840.1| 1196|Homo sapiens protein ( Homo sapiens ... 50 4e-05
AJ606362-1|CAE54481.1| 1196|Homo sapiens AHI1 protein protein. 50 4e-05
AJ459824-1|CAD30871.1| 1196|Homo sapiens AHI1 protein protein. 50 4e-05
AF251442-1|AAG44591.1| 1066|Homo sapiens mixed lineage kinase ML... 50 4e-05
BC128586-1|AAI28587.1| 748|Homo sapiens SNX26 protein protein. 50 5e-05
AL732327-7|CAI40515.1| 208|Homo sapiens SH3-domain kinase bindi... 50 5e-05
AL732327-5|CAI40513.1| 149|Homo sapiens SH3-domain kinase bindi... 50 5e-05
AK127255-1|BAC86902.1| 1007|Homo sapiens protein ( Homo sapiens ... 50 5e-05
AC069137-1|AAY24097.1| 392|Homo sapiens unknown protein. 50 5e-05
AB050785-1|BAB61771.1| 786|Homo sapiens Graf2 protein. 50 5e-05
X99657-1|CAA67971.1| 352|Homo sapiens SH3GL2 protein. 49 1e-04
X99656-1|CAA67970.1| 368|Homo sapiens SH3GL1 protein. 49 1e-04
X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyros... 49 1e-04
U94778-1|AAD00762.1| 416|Homo sapiens PEST phosphatase interact... 49 1e-04
U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase ... 49 1e-04
U65999-1|AAB86800.1| 368|Homo sapiens SH3-containing protein EE... 49 1e-04
U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinem... 49 1e-04
U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia... 49 1e-04
L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia... 49 1e-04
CR542102-1|CAG46899.1| 352|Homo sapiens SH3GL2 protein. 49 1e-04
CR542087-1|CAG46884.1| 368|Homo sapiens SH3GL1 protein. 49 1e-04
CR542086-1|CAG46883.1| 352|Homo sapiens SH3GL2 protein. 49 1e-04
BX538074-1|CAD97999.1| 290|Homo sapiens hypothetical protein pr... 49 1e-04
BT019682-1|AAV38488.1| 352|Homo sapiens SH3-domain GRB2-like 2 ... 49 1e-04
BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinem... 49 1e-04
BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinem... 49 1e-04
BC098565-1|AAH98565.1| 368|Homo sapiens SH3-domain GRB2-like 1 ... 49 1e-04
BC014387-1|AAH14387.1| 99|Homo sapiens SH3GL1 protein protein. 49 1e-04
BC001270-1|AAH01270.1| 368|Homo sapiens SH3-domain GRB2-like 1 ... 49 1e-04
BC001094-1|AAH01094.2| 99|Homo sapiens SH3GL1 protein protein. 49 1e-04
BC000089-1|AAH00089.2| 98|Homo sapiens SH3GL1 protein protein. 49 1e-04
AY364240-1|AAQ76799.1| 368|Homo sapiens SH3 domain GRB2-like 1 ... 49 1e-04
AL139115-1|CAB92765.2| 352|Homo sapiens SH3-domain GRB2-like 2 ... 49 1e-04
AL133214-1|CAH70742.1| 352|Homo sapiens SH3-domain GRB2-like 2 ... 49 1e-04
AL035422-4|CAI42359.1| 483|Homo sapiens Bruton agammaglobulinem... 49 1e-04
AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinem... 49 1e-04
AF190465-1|AAF04290.1| 368|Homo sapiens SH3-containing protein ... 49 1e-04
AF036268-1|AAC04764.1| 352|Homo sapiens EEN-B1 protein. 49 1e-04
AC007292-3|AAD24591.1| 353|Homo sapiens SH3-containing Grb-2-li... 49 1e-04
X99664-1|CAA67978.1| 347|Homo sapiens SH3GL3 protein. 49 1e-04
AL583839-7|CAI12345.1| 1004|Homo sapiens WNK lysine deficient pr... 49 1e-04
AL583839-6|CAI12344.2| 2245|Homo sapiens WNK lysine deficient pr... 49 1e-04
AL390760-2|CAH73070.1| 1004|Homo sapiens WNK lysine deficient pr... 49 1e-04
AL390760-1|CAH73069.2| 2245|Homo sapiens WNK lysine deficient pr... 49 1e-04
AL354991-2|CAI14450.1| 1004|Homo sapiens WNK lysine deficient pr... 49 1e-04
AL354991-1|CAI14449.2| 2245|Homo sapiens WNK lysine deficient pr... 49 1e-04
AF036271-1|AAC04767.1| 355|Homo sapiens EEN-B2-L3 protein. 49 1e-04
AF036270-1|AAC04766.1| 278|Homo sapiens EEN-B2-L2 protein. 49 1e-04
AF036269-1|AAC04765.1| 347|Homo sapiens EEN-B2-L1 protein. 49 1e-04
AB051547-1|BAB21851.2| 2219|Homo sapiens KIAA1760 protein protein. 49 1e-04
Z48615-1|CAA88531.1| 953|Homo sapiens serine/threonine kinase w... 48 2e-04
X90846-1|CAA62351.1| 954|Homo sapiens mixed lineage kinase 2 pr... 48 2e-04
CR533523-1|CAG38554.1| 445|Homo sapiens PACSIN2 protein. 48 2e-04
CR456536-1|CAG30422.1| 486|Homo sapiens PACSIN2 protein. 48 2e-04
BC008037-1|AAH08037.1| 486|Homo sapiens PACSIN2 protein protein. 48 2e-04
AL389984-1|CAB97538.1| 111|Homo sapiens PACSIN2 protein. 48 2e-04
AL133380-4|CAI23046.1| 1036|Homo sapiens mixed lineage kinase 4 ... 48 2e-04
AL133380-3|CAI23045.1| 570|Homo sapiens mixed lineage kinase 4 ... 48 2e-04
AL049758-1|CAI20948.1| 486|Homo sapiens protein kinase C and ca... 48 2e-04
AL022476-1|CAI20163.1| 486|Homo sapiens protein kinase C and ca... 48 2e-04
AJ311798-1|CAC84640.1| 1036|Homo sapiens mixed lineage kinase 4b... 48 2e-04
AJ311797-1|CAC84639.1| 570|Homo sapiens mixed lineage kinase 4a... 48 2e-04
AF128536-1|AAD41781.1| 486|Homo sapiens cytoplasmic phosphoprot... 48 2e-04
D86640-1|BAA13152.1| 402|Homo sapiens stac protein. 48 2e-04
BC020221-1|AAH20221.1| 402|Homo sapiens SH3 and cysteine rich d... 48 2e-04
AK024085-1|BAB14820.1| 498|Homo sapiens protein ( Homo sapiens ... 48 2e-04
AF046001-1|AAC78561.1| 478|Homo sapiens ZNF207 protein. 48 2e-04
M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1 m... 48 3e-04
K03218-1|AAA60584.1| 536|Homo sapiens SRC protein. 48 3e-04
BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma (Schmidt-... 48 3e-04
BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarco... 48 3e-04
BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein. 48 3e-04
BC004314-1|AAH04314.1| 268|Homo sapiens SORBS3 protein protein. 48 3e-04
AL133293-1|CAC34523.1| 536|Homo sapiens v-src sarcoma (Schmidt-... 48 3e-04
AF141884-1|AAD39482.1| 814|Homo sapiens oligophrenin-1 like pro... 48 3e-04
AB014521-1|BAA31596.1| 753|Homo sapiens KIAA0621 protein protein. 48 3e-04
AK128030-1|BAC87237.1| 2427|Homo sapiens protein ( Homo sapiens ... 47 4e-04
AB002307-1|BAA20768.2| 3053|Homo sapiens KIAA0309 protein. 47 4e-04
BX255972-5|CAH73103.1| 402|Homo sapiens protein kinase C and ca... 47 5e-04
BX255972-4|CAH73102.1| 444|Homo sapiens protein kinase C and ca... 47 5e-04
BC040228-1|AAH40228.1| 444|Homo sapiens PACSIN1 protein protein. 47 5e-04
AF242529-1|AAK29206.1| 444|Homo sapiens protein kinase C and ca... 47 5e-04
AB037800-1|BAA92617.2| 457|Homo sapiens KIAA1379 protein protein. 47 5e-04
AB007925-1|BAA32301.1| 1095|Homo sapiens KIAA0456 protein protein. 47 5e-04
X52207-1|CAA36457.2| 142|Homo sapiens proto-oncogene protein. 46 7e-04
M27454-1|AAA35679.1| 177|Homo sapiens tyrosine kinase protein. 46 7e-04
M19722-1|AAA52451.1| 529|Homo sapiens FGR protein. 46 7e-04
BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline ... 46 7e-04
BC033203-1|AAH33203.1| 546|Homo sapiens Unknown (protein for IM... 46 7e-04
AL109775-1|CAB52431.1| 67|Homo sapiens EEN-2B-L3 protein. 46 7e-04
AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline ... 46 7e-04
AL031729-2|CAI19617.1| 313|Homo sapiens Gardner-Rasheed feline ... 46 7e-04
AK074131-1|BAB84957.1| 573|Homo sapiens FLJ00204 protein protein. 46 7e-04
AB040927-1|BAA96018.1| 638|Homo sapiens KIAA1494 protein protein. 46 7e-04
X59656-1|CAA42199.1| 303|Homo sapiens CRKL protein. 46 9e-04
CR456423-1|CAG30309.1| 303|Homo sapiens CRKL protein. 46 9e-04
BC043500-1|AAH43500.1| 303|Homo sapiens v-crk sarcoma virus CT1... 46 9e-04
AY327406-1|AAP92798.1| 476|Homo sapiens hypothetical protein pr... 46 9e-04
U00788-1|AAB60320.1| 526|Homo sapiens neutrophil oxidase factor... 46 0.001
M32011-1|AAA36379.1| 526|Homo sapiens neutrophil oxidase factor... 46 0.001
DQ314879-1|ABC40738.1| 526|Homo sapiens neutrophil cytosolic fa... 46 0.001
BT007439-1|AAP36107.1| 526|Homo sapiens neutrophil cytosolic fa... 46 0.001
BC036044-1|AAH36044.1| 359|Homo sapiens src kinase associated p... 46 0.001
BC002893-1|AAH02893.1| 359|Homo sapiens src kinase associated p... 46 0.001
BC001606-1|AAH01606.1| 526|Homo sapiens neutrophil cytosolic fa... 46 0.001
AL137800-6|CAC19686.1| 526|Homo sapiens neutrophil cytosolic fa... 46 0.001
AJ004886-1|CAA06193.1| 359|Homo sapiens SKAP-HOM protein. 46 0.001
AF527950-1|AAM89263.1| 526|Homo sapiens p67phox-like protein pr... 46 0.001
AF072166-1|AAC39924.1| 359|Homo sapiens src kinase-associated p... 46 0.001
AF051323-1|AAC99296.1| 359|Homo sapiens Src-associated adaptor ... 46 0.001
AC003999-1|AAS02033.1| 256|Homo sapiens unknown protein. 46 0.001
AB209647-1|BAD92884.1| 598|Homo sapiens Neutrophil cytosol fact... 46 0.001
AB014486-1|BAA36194.1| 359|Homo sapiens RA70 protein. 46 0.001
AL831825-1|CAD38539.1| 211|Homo sapiens hypothetical protein pr... 45 0.002
AJ865079-1|CAI23831.1| 516|Homo sapiens proto-oncogene tyrosine... 45 0.002
AF143946-1|AAD39760.1| 2971|Homo sapiens transcriptional activat... 45 0.002
Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to S... 45 0.002
Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to S... 45 0.002
>BC116186-1|AAI16187.1| 1721|Homo sapiens intersectin 1 (SH3 domain
protein) protein.
Length = 1721
Score = 179 bits (436), Expect = 5e-44
Identities = 106/304 (34%), Positives = 153/304 (50%), Gaps = 24/304 (7%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIFPSNYVSREAAPAATSXXX 1065
A YP+ + + L F + I V+ + WW G + + G FP +YV + P S
Sbjct: 920 ALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISGPIRKSTSM 979
Query: 1066 XXXXXXXXXXXXXXXXXXXTSPPNTTPPIPASQLI----WTSNE---LAYTSVTFLLAQD 1118
+ P P + + I + S+E L + +L
Sbjct: 980 DSGSSESPASLKR------VASPAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTK 1033
Query: 1119 QKS---STPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRRKHEIVQALASYTATSPEQ 1175
+ + + + + +G+ G+ K EI Q +ASYTAT PEQ
Sbjct: 1034 KDGDWWTGTVGDKAGVFPSNYVRLKDSEGSGTAGKTGSLGK-KPEIAQVIASYTATGPEQ 1092
Query: 1176 LSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRTTPVLSS 1235
L+L GQL+++RKK GWWEGELQA+G+ RQ+GWFPA+YVK+L S G + + TP
Sbjct: 1093 LTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLL-SPG--TSKITPTEPP 1149
Query: 1236 KMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFP 1295
K AL + +V+ +Y YTAQN DEL+F K II V ++ +DP WW+GE+ G VGLFP
Sbjct: 1150 KSTAL---AAVCQVIGMYDYTAQNDDELAFNKGQIINVLNK-EDPDWWKGEVNGQVGLFP 1205
Query: 1296 SNYV 1299
SNYV
Sbjct: 1206 SNYV 1209
Score = 134 bits (323), Expect = 3e-30
Identities = 82/211 (38%), Positives = 110/211 (52%), Gaps = 10/211 (4%)
Query: 242 PIMSSQPLI--SASTISAQPLGTMQPLIGTAPPIMGATQALIQSPPLSGPQQPAPVTAAS 299
P+M QP+ SA + +M PL AP MG+ + SP L A V +
Sbjct: 100 PVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLA 159
Query: 300 FGGXXXXXXXXXXXXGQPVTSTPIAALNKEVISKPGSVVTSP---EVPMGVMSPPPM-EW 355
G P + P ++ S PGS + + V S PP+ EW
Sbjct: 160 NGAPPVIQPLPAFA--HPAATLPKSSSFSR--SGPGSQLNTKLQKAQSFDVASVPPVAEW 215
Query: 356 GVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLG 415
VPQ +LKY QLFN+ D+ +G +G QAR+I++QS LPQ LA IW L+D+D DGKL
Sbjct: 216 AVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLT 275
Query: 416 CEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
EEF+LAM+L + A G+P+P LPPE IPP
Sbjct: 276 AEEFILAMHLIDVAMSGQPLPPVLPPEYIPP 306
Score = 106 bits (254), Expect = 6e-22
Identities = 47/88 (53%), Positives = 61/88 (69%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGK 63
D W I E AK + F +L P++G +TG+QA+ F QS LP PVL QIW+LAD N DG+
Sbjct: 13 DIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGR 72
Query: 64 LDLKEFSIACKIINLKLRGLEVPKMLPP 91
+D EFSIA K+I LKL+G ++P LPP
Sbjct: 73 MDQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 106 bits (254), Expect = 6e-22
Identities = 83/291 (28%), Positives = 126/291 (43%), Gaps = 34/291 (11%)
Query: 928 RGQSGWFPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDP 987
+GQ GWFP+SYV+ ++ P + T ++ +S+ +L V P
Sbjct: 955 QGQKGWFPKSYVKLISGP----------IRKSTSMDS--------GSSESPASLKRVASP 996
Query: 988 GRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIF 1047
++PV GE +IA Y Y SSE GDL F+ G+ I V ++DGDWWTG +G + G+F
Sbjct: 997 A---AKPVV---SGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTVGDKAGVF 1050
Query: 1048 PSNYVSREAAPAATSXXXXXXXXXXXXXXXXXXXXXXTSPPNTTPPIPASQLIWTSNELA 1107
PSNYV + + + + T P T LI N
Sbjct: 1051 PSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGG 1110
Query: 1108 YTSVTFLLAQDQKSSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRRKHEIVQALAS 1167
+ L A+ +K I A + + + I +
Sbjct: 1111 WWEGE-LQARGKKRQ--IGWFPANYVKLLSPGTSKITPTEPPKSTALAAVCQVI--GMYD 1165
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKV 1218
YTA + ++L+ KGQ++ V K D WW+GE+ N QVG FP++YVK+
Sbjct: 1166 YTAQNDDELAFNKGQIINVLNKEDPDWWKGEV-----NGQVGLFPSNYVKL 1211
Score = 96.7 bits (230), Expect = 5e-19
Identities = 95/353 (26%), Positives = 148/353 (41%), Gaps = 46/353 (13%)
Query: 980 ALPAVVDPGRTVSE---PVSVEDDGE--FYIASYPYSSS-------EPGDLVFEAGERIE 1027
A PAV P T + +S +++ + +Y A YP+ S +PGD+V GE ++
Sbjct: 716 AKPAVQAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMVKGEWVD 775
Query: 1028 VVRR-DGDWWTGRIGARTGIFPSNYVSR---EAAPAATSXXXXXXXXXXXXXXXXXX--- 1080
+ + W G + +TG FP+NY + PA
Sbjct: 776 ESQTGEPGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTDSTSAPAPKLALRETPAP 835
Query: 1081 XXXXTSPPNTTPPIPAS-QLIW--TSNELAYTSVTFLLAQDQKSSTPISSEVAMITDXXX 1137
+S P+TTP A W ++NE T A + P + ++
Sbjct: 836 LAVTSSEPSTTPNNWADFSSTWPTSTNEKPETDNWDAWAAQPSLTVPSAGQLRQ-----R 890
Query: 1138 XXXXXXXXXDSGRDSVTGR-RKHEIVQALASYT--ATSPEQLSLMKGQLLVVRKKADSGW 1194
S V G+ K E +QA A Y A L+ K ++ V ++ D W
Sbjct: 891 SAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDM-W 949
Query: 1195 WEGELQAKGRNRQVGWFPASYVKVL-----QSSGRTSGRTTPVLSSKMDALPTETVI--- 1246
W GE+Q Q GWFP SYVK++ +S+ SG + S K A P +
Sbjct: 950 WFGEVQG-----QKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKPVVSG 1004
Query: 1247 DKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
++ +A+Y Y + +L+F++ D+I VT + D WW G + G+FPSNYV
Sbjct: 1005 EEFIAMYTYESSEQGDLTFQQGDVILVTKKDGD--WWTGTVGDKAGVFPSNYV 1055
Score = 71.3 bits (167), Expect = 2e-11
Identities = 36/87 (41%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 355 WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKL 414
W + ++ K+ Q F++ + +G +G QAR+ QS LPQ LAQIWALAD++ DG++
Sbjct: 15 WAITVEERAKHDQQFHSL-KPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRM 73
Query: 415 GCEEFVLAMYLCEKATQGEPVPARLPP 441
EF +AM L + QG +P+ LPP
Sbjct: 74 DQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 69.7 bits (163), Expect = 6e-11
Identities = 32/90 (35%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F + ++G+LTG QA+ ++QS LP L IW+L+D + DGKL
Sbjct: 215 WAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKL 274
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A +I++ + G +P +LPP I
Sbjct: 275 TAEEFILAMHLIDVAMSGQPLPPVLPPEYI 304
Score = 63.3 bits (147), Expect = 5e-09
Identities = 50/146 (34%), Positives = 75/146 (51%), Gaps = 25/146 (17%)
Query: 1165 LASYTATSPEQ--LSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSS 1222
+A YT S EQ L+ +G +++V KK D WW G + K G FP++YV++ S
Sbjct: 1008 IAMYTYESSEQGDLTFQQGDVILVTKK-DGDWWTGTVGDKA-----GVFPSNYVRLKDSE 1061
Query: 1223 GRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDP-A 1281
G + T L K + I +V+A YTA ++L+ +I + R ++P
Sbjct: 1062 GSGTAGKTGSLGKKPE-------IAQVIA--SYTATGPEQLTLAPGQLILI--RKKNPGG 1110
Query: 1282 WWQGEL--RG---MVGLFPSNYVTKL 1302
WW+GEL RG +G FP+NYV L
Sbjct: 1111 WWEGELQARGKKRQIGWFPANYVKLL 1136
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/90 (31%), Positives = 52/90 (57%)
Query: 633 QCQLEWEKKRTRELEALRSEEQSKVLSLKAKCQSLSAQLGAESVRCSTLAASIRDTRTAV 692
Q QLEWE+ R +EL R++EQ ++ LKAK ++L +L A + + L ++D R +
Sbjct: 444 QRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRL 503
Query: 693 AADKRTIDGMRSDRDSSMAEMQQLKARVKE 722
++ I+ R+ +AE+ L+ +++E
Sbjct: 504 TTQRQEIESTNKSRELRIAEITHLQQQLQE 533
Score = 52.0 bits (119), Expect = 1e-05
Identities = 24/54 (44%), Positives = 36/54 (66%), Gaps = 3/54 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
ALYP+ A+ + L+F K+D+I V + Q WW GE++G G FP +YV KL++
Sbjct: 920 ALYPWRAKKDNHLNFNKNDVITVLE--QQDMWWFGEVQGQKGWFPKSYV-KLIS 970
Score = 50.4 bits (115), Expect = 4e-05
Identities = 24/58 (41%), Positives = 36/58 (62%), Gaps = 6/58 (10%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAV----TDRSQ--DPAWWQGELRGMVGLFPSNYVTKL 1302
ALYP+ +++ DE++ + DI+ V D SQ +P W GEL+G G FP+NY K+
Sbjct: 747 ALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804
Score = 46.4 bits (105), Expect = 7e-04
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 9/85 (10%)
Query: 887 WRCVYPFVGRSADELSVQPGDLIVXXXXXXXXXXXX----XXXXXRGQSGWFPESYVE-- 940
+R +YPF RS DE+++QPGD+++ +G++GWFP +Y E
Sbjct: 745 YRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804
Query: 941 ---DLNAPTAFVTEVIETLEPKTQL 962
++ AP VT+ PK L
Sbjct: 805 PENEVPAPVKPVTDSTSAPAPKLAL 829
Score = 33.9 bits (74), Expect = 3.8
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 466 RRENMARGQAELERRRTQLADAQMKEKVRGRGLNQSQ 502
+REN RG ELE+RR L + Q KE+ R L +++
Sbjct: 354 KRENFERGNLELEKRRQALLEQQRKEQERLAQLERAE 390
>AF114488-1|AAD29953.1| 1220|Homo sapiens intersectin short isoform
protein.
Length = 1220
Score = 179 bits (436), Expect = 5e-44
Identities = 106/304 (34%), Positives = 153/304 (50%), Gaps = 24/304 (7%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIFPSNYVSREAAPAATSXXX 1065
A YP+ + + L F + I V+ + WW G + + G FP +YV + P S
Sbjct: 920 ALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISGPIRKSTSM 979
Query: 1066 XXXXXXXXXXXXXXXXXXXTSPPNTTPPIPASQLI----WTSNE---LAYTSVTFLLAQD 1118
+ P P + + I + S+E L + +L
Sbjct: 980 DSGSSESPASLKR------VASPAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTK 1033
Query: 1119 QKS---STPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRRKHEIVQALASYTATSPEQ 1175
+ + + + + +G+ G+ K EI Q +ASYTAT PEQ
Sbjct: 1034 KDGDWWTGTVGDKAGVFPSNYVRLKDSEGSGTAGKTGSLGK-KPEIAQVIASYTATGPEQ 1092
Query: 1176 LSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRTTPVLSS 1235
L+L GQL+++RKK GWWEGELQA+G+ RQ+GWFPA+YVK+L S G + + TP
Sbjct: 1093 LTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLL-SPG--TSKITPTEPP 1149
Query: 1236 KMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFP 1295
K AL + +V+ +Y YTAQN DEL+F K II V ++ +DP WW+GE+ G VGLFP
Sbjct: 1150 KSTAL---AAVCQVIGMYDYTAQNDDELAFNKGQIINVLNK-EDPDWWKGEVNGQVGLFP 1205
Query: 1296 SNYV 1299
SNYV
Sbjct: 1206 SNYV 1209
Score = 134 bits (323), Expect = 3e-30
Identities = 82/211 (38%), Positives = 110/211 (52%), Gaps = 10/211 (4%)
Query: 242 PIMSSQPLI--SASTISAQPLGTMQPLIGTAPPIMGATQALIQSPPLSGPQQPAPVTAAS 299
P+M QP+ SA + +M PL AP MG+ + SP L A V +
Sbjct: 100 PVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLA 159
Query: 300 FGGXXXXXXXXXXXXGQPVTSTPIAALNKEVISKPGSVVTSP---EVPMGVMSPPPM-EW 355
G P + P ++ S PGS + + V S PP+ EW
Sbjct: 160 NGAPPVIQPLPAFA--HPAATLPKSSSFSR--SGPGSQLNTKLQKAQSFDVASVPPVAEW 215
Query: 356 GVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLG 415
VPQ +LKY QLFN+ D+ +G +G QAR+I++QS LPQ LA IW L+D+D DGKL
Sbjct: 216 AVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLT 275
Query: 416 CEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
EEF+LAM+L + A G+P+P LPPE IPP
Sbjct: 276 AEEFILAMHLIDVAMSGQPLPPVLPPEYIPP 306
Score = 106 bits (254), Expect = 6e-22
Identities = 47/88 (53%), Positives = 61/88 (69%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGK 63
D W I E AK + F +L P++G +TG+QA+ F QS LP PVL QIW+LAD N DG+
Sbjct: 13 DIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGR 72
Query: 64 LDLKEFSIACKIINLKLRGLEVPKMLPP 91
+D EFSIA K+I LKL+G ++P LPP
Sbjct: 73 MDQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 106 bits (254), Expect = 6e-22
Identities = 83/291 (28%), Positives = 126/291 (43%), Gaps = 34/291 (11%)
Query: 928 RGQSGWFPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDP 987
+GQ GWFP+SYV+ ++ P + T ++ +S+ +L V P
Sbjct: 955 QGQKGWFPKSYVKLISGP----------IRKSTSMDS--------GSSESPASLKRVASP 996
Query: 988 GRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIF 1047
++PV GE +IA Y Y SSE GDL F+ G+ I V ++DGDWWTG +G + G+F
Sbjct: 997 A---AKPVV---SGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTVGDKAGVF 1050
Query: 1048 PSNYVSREAAPAATSXXXXXXXXXXXXXXXXXXXXXXTSPPNTTPPIPASQLIWTSNELA 1107
PSNYV + + + + T P T LI N
Sbjct: 1051 PSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGG 1110
Query: 1108 YTSVTFLLAQDQKSSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRRKHEIVQALAS 1167
+ L A+ +K I A + + + I +
Sbjct: 1111 WWEGE-LQARGKKRQ--IGWFPANYVKLLSPGTSKITPTEPPKSTALAAVCQVI--GMYD 1165
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKV 1218
YTA + ++L+ KGQ++ V K D WW+GE+ N QVG FP++YVK+
Sbjct: 1166 YTAQNDDELAFNKGQIINVLNKEDPDWWKGEV-----NGQVGLFPSNYVKL 1211
Score = 96.7 bits (230), Expect = 5e-19
Identities = 95/353 (26%), Positives = 148/353 (41%), Gaps = 46/353 (13%)
Query: 980 ALPAVVDPGRTVSE---PVSVEDDGE--FYIASYPYSSS-------EPGDLVFEAGERIE 1027
A PAV P T + +S +++ + +Y A YP+ S +PGD+V GE ++
Sbjct: 716 AKPAVQAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMVKGEWVD 775
Query: 1028 VVRR-DGDWWTGRIGARTGIFPSNYVSR---EAAPAATSXXXXXXXXXXXXXXXXXX--- 1080
+ + W G + +TG FP+NY + PA
Sbjct: 776 ESQTGEPGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTDSTSAPAPKLALRETPAP 835
Query: 1081 XXXXTSPPNTTPPIPAS-QLIW--TSNELAYTSVTFLLAQDQKSSTPISSEVAMITDXXX 1137
+S P+TTP A W ++NE T A + P + ++
Sbjct: 836 LAVTSSEPSTTPNNWADFSSTWPTSTNEKPETDNWDAWAAQPSLTVPSAGQLRQ-----R 890
Query: 1138 XXXXXXXXXDSGRDSVTGR-RKHEIVQALASYT--ATSPEQLSLMKGQLLVVRKKADSGW 1194
S V G+ K E +QA A Y A L+ K ++ V ++ D W
Sbjct: 891 SAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDM-W 949
Query: 1195 WEGELQAKGRNRQVGWFPASYVKVL-----QSSGRTSGRTTPVLSSKMDALPTETVI--- 1246
W GE+Q Q GWFP SYVK++ +S+ SG + S K A P +
Sbjct: 950 WFGEVQG-----QKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKPVVSG 1004
Query: 1247 DKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
++ +A+Y Y + +L+F++ D+I VT + D WW G + G+FPSNYV
Sbjct: 1005 EEFIAMYTYESSEQGDLTFQQGDVILVTKKDGD--WWTGTVGDKAGVFPSNYV 1055
Score = 71.3 bits (167), Expect = 2e-11
Identities = 36/87 (41%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 355 WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKL 414
W + ++ K+ Q F++ + +G +G QAR+ QS LPQ LAQIWALAD++ DG++
Sbjct: 15 WAITVEERAKHDQQFHSL-KPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRM 73
Query: 415 GCEEFVLAMYLCEKATQGEPVPARLPP 441
EF +AM L + QG +P+ LPP
Sbjct: 74 DQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 69.7 bits (163), Expect = 6e-11
Identities = 32/90 (35%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F + ++G+LTG QA+ ++QS LP L IW+L+D + DGKL
Sbjct: 215 WAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKL 274
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A +I++ + G +P +LPP I
Sbjct: 275 TAEEFILAMHLIDVAMSGQPLPPVLPPEYI 304
Score = 63.3 bits (147), Expect = 5e-09
Identities = 50/146 (34%), Positives = 75/146 (51%), Gaps = 25/146 (17%)
Query: 1165 LASYTATSPEQ--LSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSS 1222
+A YT S EQ L+ +G +++V KK D WW G + K G FP++YV++ S
Sbjct: 1008 IAMYTYESSEQGDLTFQQGDVILVTKK-DGDWWTGTVGDKA-----GVFPSNYVRLKDSE 1061
Query: 1223 GRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDP-A 1281
G + T L K + I +V+A YTA ++L+ +I + R ++P
Sbjct: 1062 GSGTAGKTGSLGKKPE-------IAQVIA--SYTATGPEQLTLAPGQLILI--RKKNPGG 1110
Query: 1282 WWQGEL--RG---MVGLFPSNYVTKL 1302
WW+GEL RG +G FP+NYV L
Sbjct: 1111 WWEGELQARGKKRQIGWFPANYVKLL 1136
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/90 (31%), Positives = 52/90 (57%)
Query: 633 QCQLEWEKKRTRELEALRSEEQSKVLSLKAKCQSLSAQLGAESVRCSTLAASIRDTRTAV 692
Q QLEWE+ R +EL R++EQ ++ LKAK ++L +L A + + L ++D R +
Sbjct: 444 QRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRL 503
Query: 693 AADKRTIDGMRSDRDSSMAEMQQLKARVKE 722
++ I+ R+ +AE+ L+ +++E
Sbjct: 504 TTQRQEIESTNKSRELRIAEITHLQQQLQE 533
Score = 52.0 bits (119), Expect = 1e-05
Identities = 24/54 (44%), Positives = 36/54 (66%), Gaps = 3/54 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
ALYP+ A+ + L+F K+D+I V + Q WW GE++G G FP +YV KL++
Sbjct: 920 ALYPWRAKKDNHLNFNKNDVITVLE--QQDMWWFGEVQGQKGWFPKSYV-KLIS 970
Score = 50.4 bits (115), Expect = 4e-05
Identities = 24/58 (41%), Positives = 36/58 (62%), Gaps = 6/58 (10%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAV----TDRSQ--DPAWWQGELRGMVGLFPSNYVTKL 1302
ALYP+ +++ DE++ + DI+ V D SQ +P W GEL+G G FP+NY K+
Sbjct: 747 ALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804
Score = 46.4 bits (105), Expect = 7e-04
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 9/85 (10%)
Query: 887 WRCVYPFVGRSADELSVQPGDLIVXXXXXXXXXXXX----XXXXXRGQSGWFPESYVE-- 940
+R +YPF RS DE+++QPGD+++ +G++GWFP +Y E
Sbjct: 745 YRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804
Query: 941 ---DLNAPTAFVTEVIETLEPKTQL 962
++ AP VT+ PK L
Sbjct: 805 PENEVPAPVKPVTDSTSAPAPKLAL 829
Score = 33.9 bits (74), Expect = 3.8
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 466 RRENMARGQAELERRRTQLADAQMKEKVRGRGLNQSQ 502
+REN RG ELE+RR L + Q KE+ R L +++
Sbjct: 354 KRENFERGNLELEKRRQALLEQQRKEQERLAQLERAE 390
>AF114487-1|AAD29952.1| 1721|Homo sapiens intersectin long isoform
protein.
Length = 1721
Score = 179 bits (436), Expect = 5e-44
Identities = 106/304 (34%), Positives = 153/304 (50%), Gaps = 24/304 (7%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIFPSNYVSREAAPAATSXXX 1065
A YP+ + + L F + I V+ + WW G + + G FP +YV + P S
Sbjct: 920 ALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISGPIRKSTSM 979
Query: 1066 XXXXXXXXXXXXXXXXXXXTSPPNTTPPIPASQLI----WTSNE---LAYTSVTFLLAQD 1118
+ P P + + I + S+E L + +L
Sbjct: 980 DSGSSESPASLKR------VASPAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTK 1033
Query: 1119 QKS---STPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRRKHEIVQALASYTATSPEQ 1175
+ + + + + +G+ G+ K EI Q +ASYTAT PEQ
Sbjct: 1034 KDGDWWTGTVGDKAGVFPSNYVRLKDSEGSGTAGKTGSLGK-KPEIAQVIASYTATGPEQ 1092
Query: 1176 LSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRTTPVLSS 1235
L+L GQL+++RKK GWWEGELQA+G+ RQ+GWFPA+YVK+L S G + + TP
Sbjct: 1093 LTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLL-SPG--TSKITPTEPP 1149
Query: 1236 KMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFP 1295
K AL + +V+ +Y YTAQN DEL+F K II V ++ +DP WW+GE+ G VGLFP
Sbjct: 1150 KSTAL---AAVCQVIGMYDYTAQNDDELAFNKGQIINVLNK-EDPDWWKGEVNGQVGLFP 1205
Query: 1296 SNYV 1299
SNYV
Sbjct: 1206 SNYV 1209
Score = 134 bits (323), Expect = 3e-30
Identities = 82/211 (38%), Positives = 110/211 (52%), Gaps = 10/211 (4%)
Query: 242 PIMSSQPLI--SASTISAQPLGTMQPLIGTAPPIMGATQALIQSPPLSGPQQPAPVTAAS 299
P+M QP+ SA + +M PL AP MG+ + SP L A V +
Sbjct: 100 PVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLA 159
Query: 300 FGGXXXXXXXXXXXXGQPVTSTPIAALNKEVISKPGSVVTSP---EVPMGVMSPPPM-EW 355
G P + P ++ S PGS + + V S PP+ EW
Sbjct: 160 NGAPPVIQPLPAFA--HPAATLPKSSSFSR--SGPGSQLNTKLQKAQSFDVASVPPVAEW 215
Query: 356 GVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLG 415
VPQ +LKY QLFN+ D+ +G +G QAR+I++QS LPQ LA IW L+D+D DGKL
Sbjct: 216 AVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLT 275
Query: 416 CEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
EEF+LAM+L + A G+P+P LPPE IPP
Sbjct: 276 AEEFILAMHLIDVAMSGQPLPPVLPPEYIPP 306
Score = 106 bits (254), Expect = 6e-22
Identities = 47/88 (53%), Positives = 61/88 (69%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGK 63
D W I E AK + F +L P++G +TG+QA+ F QS LP PVL QIW+LAD N DG+
Sbjct: 13 DIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGR 72
Query: 64 LDLKEFSIACKIINLKLRGLEVPKMLPP 91
+D EFSIA K+I LKL+G ++P LPP
Sbjct: 73 MDQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 106 bits (254), Expect = 6e-22
Identities = 83/291 (28%), Positives = 126/291 (43%), Gaps = 34/291 (11%)
Query: 928 RGQSGWFPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDP 987
+GQ GWFP+SYV+ ++ P + T ++ +S+ +L V P
Sbjct: 955 QGQKGWFPKSYVKLISGP----------IRKSTSMDS--------GSSESPASLKRVASP 996
Query: 988 GRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIF 1047
++PV GE +IA Y Y SSE GDL F+ G+ I V ++DGDWWTG +G + G+F
Sbjct: 997 A---AKPVV---SGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTVGDKAGVF 1050
Query: 1048 PSNYVSREAAPAATSXXXXXXXXXXXXXXXXXXXXXXTSPPNTTPPIPASQLIWTSNELA 1107
PSNYV + + + + T P T LI N
Sbjct: 1051 PSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGG 1110
Query: 1108 YTSVTFLLAQDQKSSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRRKHEIVQALAS 1167
+ L A+ +K I A + + + I +
Sbjct: 1111 WWEGE-LQARGKKRQ--IGWFPANYVKLLSPGTSKITPTEPPKSTALAAVCQVI--GMYD 1165
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKV 1218
YTA + ++L+ KGQ++ V K D WW+GE+ N QVG FP++YVK+
Sbjct: 1166 YTAQNDDELAFNKGQIINVLNKEDPDWWKGEV-----NGQVGLFPSNYVKL 1211
Score = 96.7 bits (230), Expect = 5e-19
Identities = 95/353 (26%), Positives = 148/353 (41%), Gaps = 46/353 (13%)
Query: 980 ALPAVVDPGRTVSE---PVSVEDDGE--FYIASYPYSSS-------EPGDLVFEAGERIE 1027
A PAV P T + +S +++ + +Y A YP+ S +PGD+V GE ++
Sbjct: 716 AKPAVQAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMVKGEWVD 775
Query: 1028 VVRR-DGDWWTGRIGARTGIFPSNYVSR---EAAPAATSXXXXXXXXXXXXXXXXXX--- 1080
+ + W G + +TG FP+NY + PA
Sbjct: 776 ESQTGEPGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTDSTSAPAPKLALRETPAP 835
Query: 1081 XXXXTSPPNTTPPIPAS-QLIW--TSNELAYTSVTFLLAQDQKSSTPISSEVAMITDXXX 1137
+S P+TTP A W ++NE T A + P + ++
Sbjct: 836 LAVTSSEPSTTPNNWADFSSTWPTSTNEKPETDNWDAWAAQPSLTVPSAGQLRQ-----R 890
Query: 1138 XXXXXXXXXDSGRDSVTGR-RKHEIVQALASYT--ATSPEQLSLMKGQLLVVRKKADSGW 1194
S V G+ K E +QA A Y A L+ K ++ V ++ D W
Sbjct: 891 SAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDM-W 949
Query: 1195 WEGELQAKGRNRQVGWFPASYVKVL-----QSSGRTSGRTTPVLSSKMDALPTETVI--- 1246
W GE+Q Q GWFP SYVK++ +S+ SG + S K A P +
Sbjct: 950 WFGEVQG-----QKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKPVVSG 1004
Query: 1247 DKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
++ +A+Y Y + +L+F++ D+I VT + D WW G + G+FPSNYV
Sbjct: 1005 EEFIAMYTYESSEQGDLTFQQGDVILVTKKDGD--WWTGTVGDKAGVFPSNYV 1055
Score = 71.3 bits (167), Expect = 2e-11
Identities = 36/87 (41%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 355 WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKL 414
W + ++ K+ Q F++ + +G +G QAR+ QS LPQ LAQIWALAD++ DG++
Sbjct: 15 WAITVEERAKHDQQFHSL-KPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRM 73
Query: 415 GCEEFVLAMYLCEKATQGEPVPARLPP 441
EF +AM L + QG +P+ LPP
Sbjct: 74 DQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 69.7 bits (163), Expect = 6e-11
Identities = 32/90 (35%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F + ++G+LTG QA+ ++QS LP L IW+L+D + DGKL
Sbjct: 215 WAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKL 274
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A +I++ + G +P +LPP I
Sbjct: 275 TAEEFILAMHLIDVAMSGQPLPPVLPPEYI 304
Score = 63.3 bits (147), Expect = 5e-09
Identities = 50/146 (34%), Positives = 75/146 (51%), Gaps = 25/146 (17%)
Query: 1165 LASYTATSPEQ--LSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSS 1222
+A YT S EQ L+ +G +++V KK D WW G + K G FP++YV++ S
Sbjct: 1008 IAMYTYESSEQGDLTFQQGDVILVTKK-DGDWWTGTVGDKA-----GVFPSNYVRLKDSE 1061
Query: 1223 GRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDP-A 1281
G + T L K + I +V+A YTA ++L+ +I + R ++P
Sbjct: 1062 GSGTAGKTGSLGKKPE-------IAQVIA--SYTATGPEQLTLAPGQLILI--RKKNPGG 1110
Query: 1282 WWQGEL--RG---MVGLFPSNYVTKL 1302
WW+GEL RG +G FP+NYV L
Sbjct: 1111 WWEGELQARGKKRQIGWFPANYVKLL 1136
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/90 (31%), Positives = 52/90 (57%)
Query: 633 QCQLEWEKKRTRELEALRSEEQSKVLSLKAKCQSLSAQLGAESVRCSTLAASIRDTRTAV 692
Q QLEWE+ R +EL R++EQ ++ LKAK ++L +L A + + L ++D R +
Sbjct: 444 QRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRL 503
Query: 693 AADKRTIDGMRSDRDSSMAEMQQLKARVKE 722
++ I+ R+ +AE+ L+ +++E
Sbjct: 504 TTQRQEIESTNKSRELRIAEITHLQQQLQE 533
Score = 52.0 bits (119), Expect = 1e-05
Identities = 24/54 (44%), Positives = 36/54 (66%), Gaps = 3/54 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
ALYP+ A+ + L+F K+D+I V + Q WW GE++G G FP +YV KL++
Sbjct: 920 ALYPWRAKKDNHLNFNKNDVITVLE--QQDMWWFGEVQGQKGWFPKSYV-KLIS 970
Score = 50.4 bits (115), Expect = 4e-05
Identities = 24/58 (41%), Positives = 36/58 (62%), Gaps = 6/58 (10%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAV----TDRSQ--DPAWWQGELRGMVGLFPSNYVTKL 1302
ALYP+ +++ DE++ + DI+ V D SQ +P W GEL+G G FP+NY K+
Sbjct: 747 ALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804
Score = 46.4 bits (105), Expect = 7e-04
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 9/85 (10%)
Query: 887 WRCVYPFVGRSADELSVQPGDLIVXXXXXXXXXXXX----XXXXXRGQSGWFPESYVE-- 940
+R +YPF RS DE+++QPGD+++ +G++GWFP +Y E
Sbjct: 745 YRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804
Query: 941 ---DLNAPTAFVTEVIETLEPKTQL 962
++ AP VT+ PK L
Sbjct: 805 PENEVPAPVKPVTDSTSAPAPKLAL 829
Score = 33.9 bits (74), Expect = 3.8
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 466 RRENMARGQAELERRRTQLADAQMKEKVRGRGLNQSQ 502
+REN RG ELE+RR L + Q KE+ R L +++
Sbjct: 354 KRENFERGNLELEKRRQALLEQQRKEQERLAQLERAE 390
>DQ679757-1|ABG74698.1| 1215|Homo sapiens intersectin 1 short form
variant 5 protein.
Length = 1215
Score = 179 bits (435), Expect = 7e-44
Identities = 104/304 (34%), Positives = 151/304 (49%), Gaps = 24/304 (7%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIFPSNYVSREAAPAATSXXX 1065
A YP+ + + L F + I V+ + WW G + + G FP +YV + P S
Sbjct: 915 ALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISGPIRKSTSM 974
Query: 1066 XXXXXXXXXXXXXXXXXXXTSPPNTTPPIPASQLI----WTSNE---LAYTSVTFLLAQD 1118
+ P P + + I + S+E L + +L
Sbjct: 975 DSGSSESPASLKR------VASPAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTK 1028
Query: 1119 QKS---STPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRRKHEIVQALASYTATSPEQ 1175
+ + + + + +G+ G+ K EI Q +ASYTAT PEQ
Sbjct: 1029 KDGDWWTGTVGDKAGVFPSNYVRLKDSEGSGTAGKTGSLGK-KPEIAQVIASYTATGPEQ 1087
Query: 1176 LSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRTTPVLSS 1235
L+L GQL+++RKK GWWEGELQA+G+ RQ+GWFPA+YVK+L + + TP
Sbjct: 1088 LTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLNPG---TSKITPTEPP 1144
Query: 1236 KMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFP 1295
K AL + +V+ +Y YTAQN DEL+F K II V ++ +DP WW+GE+ G VGLFP
Sbjct: 1145 KSTAL---AAVCQVIGMYDYTAQNDDELAFNKGQIINVLNK-EDPDWWKGEVNGQVGLFP 1200
Query: 1296 SNYV 1299
SNYV
Sbjct: 1201 SNYV 1204
Score = 133 bits (322), Expect = 3e-30
Identities = 82/211 (38%), Positives = 110/211 (52%), Gaps = 10/211 (4%)
Query: 242 PIMSSQPLI--SASTISAQPLGTMQPLIGTAPPIMGATQALIQSPPLSGPQQPAPVTAAS 299
P+M QP+ SA + +M PL AP MG+ + SP L A V +
Sbjct: 100 PVMKQQPVAISSAPPFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLA 159
Query: 300 FGGXXXXXXXXXXXXGQPVTSTPIAALNKEVISKPGSVVTSP---EVPMGVMSPPPM-EW 355
G P + P ++ S PGS + + V S PP+ EW
Sbjct: 160 NGAPPVIQPLPAFA--HPAATLPKSSSFSR--SGPGSQLNTKLQKAQSFDVASVPPVAEW 215
Query: 356 GVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLG 415
VPQ +LKY QLFN+ D+ +G +G QAR+I++QS LPQ LA IW L+D+D DGKL
Sbjct: 216 AVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLT 275
Query: 416 CEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
EEF+LAM+L + A G+P+P LPPE IPP
Sbjct: 276 AEEFILAMHLIDVAMSGQPLPPVLPPEYIPP 306
Score = 106 bits (254), Expect = 6e-22
Identities = 47/88 (53%), Positives = 61/88 (69%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGK 63
D W I E AK + F +L P++G +TG+QA+ F QS LP PVL QIW+LAD N DG+
Sbjct: 13 DIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGR 72
Query: 64 LDLKEFSIACKIINLKLRGLEVPKMLPP 91
+D EFSIA K+I LKL+G ++P LPP
Sbjct: 73 MDQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 105 bits (253), Expect = 8e-22
Identities = 83/291 (28%), Positives = 126/291 (43%), Gaps = 34/291 (11%)
Query: 928 RGQSGWFPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDP 987
+GQ GWFP+SYV+ ++ P + T ++ +S+ +L V P
Sbjct: 950 QGQKGWFPKSYVKLISGP----------IRKSTSMDS--------GSSESPASLKRVASP 991
Query: 988 GRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIF 1047
++PV GE +IA Y Y SSE GDL F+ G+ I V ++DGDWWTG +G + G+F
Sbjct: 992 A---AKPVV---SGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTVGDKAGVF 1045
Query: 1048 PSNYVSREAAPAATSXXXXXXXXXXXXXXXXXXXXXXTSPPNTTPPIPASQLIWTSNELA 1107
PSNYV + + + + T P T LI N
Sbjct: 1046 PSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGG 1105
Query: 1108 YTSVTFLLAQDQKSSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRRKHEIVQALAS 1167
+ L A+ +K I A + + + I +
Sbjct: 1106 WWEGE-LQARGKKRQ--IGWFPANYVKLLNPGTSKITPTEPPKSTALAAVCQVI--GMYD 1160
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKV 1218
YTA + ++L+ KGQ++ V K D WW+GE+ N QVG FP++YVK+
Sbjct: 1161 YTAQNDDELAFNKGQIINVLNKEDPDWWKGEV-----NGQVGLFPSNYVKL 1206
Score = 94.7 bits (225), Expect = 2e-18
Identities = 92/348 (26%), Positives = 146/348 (41%), Gaps = 41/348 (11%)
Query: 980 ALPAVVDPGRTVSE---PVSVEDDGE--FYIASYPYSSSEPGDLVFEAGERIEVVR-RDG 1033
A PAV P T + +S +++ + +Y A YP+ S ++ + G+ + V + G
Sbjct: 716 AKPAVQAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMVDESQTG 775
Query: 1034 D--WWTGRIGARTGIFPSNYVSR---EAAPAATSXXXXXXXXXXXXXXXXXX---XXXXT 1085
+ W G + +TG FP+NY + PA +
Sbjct: 776 EPGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTDSTSAPAPKLALRETPAPLAVTS 835
Query: 1086 SPPNTTPPIPAS-QLIW--TSNELAYTSVTFLLAQDQKSSTPISSEVAMITDXXXXXXXX 1142
S P+TTP A W ++NE T A + P + ++
Sbjct: 836 SEPSTTPNNWADFSSTWPTSTNEKPETDNWDAWAAQPSLTVPSAGQLRQ-----RSAFTP 890
Query: 1143 XXXXDSGRDSVTGR-RKHEIVQALASYT--ATSPEQLSLMKGQLLVVRKKADSGWWEGEL 1199
S V G+ K E +QA A Y A L+ K ++ V ++ D WW GE+
Sbjct: 891 ATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDM-WWFGEV 949
Query: 1200 QAKGRNRQVGWFPASYVKVL-----QSSGRTSGRTTPVLSSKMDALPTETVI---DKVVA 1251
Q Q GWFP SYVK++ +S+ SG + S K A P + ++ +A
Sbjct: 950 QG-----QKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKPVVSGEEFIA 1004
Query: 1252 LYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+Y Y + +L+F++ D+I VT + D WW G + G+FPSNYV
Sbjct: 1005 MYTYESSEQGDLTFQQGDVILVTKKDGD--WWTGTVGDKAGVFPSNYV 1050
Score = 71.3 bits (167), Expect = 2e-11
Identities = 36/87 (41%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 355 WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKL 414
W + ++ K+ Q F++ + +G +G QAR+ QS LPQ LAQIWALAD++ DG++
Sbjct: 15 WAITVEERAKHDQQFHSL-KPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRM 73
Query: 415 GCEEFVLAMYLCEKATQGEPVPARLPP 441
EF +AM L + QG +P+ LPP
Sbjct: 74 DQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 69.7 bits (163), Expect = 6e-11
Identities = 32/90 (35%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F + ++G+LTG QA+ ++QS LP L IW+L+D + DGKL
Sbjct: 215 WAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKL 274
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A +I++ + G +P +LPP I
Sbjct: 275 TAEEFILAMHLIDVAMSGQPLPPVLPPEYI 304
Score = 64.9 bits (151), Expect = 2e-09
Identities = 52/148 (35%), Positives = 78/148 (52%), Gaps = 26/148 (17%)
Query: 1165 LASYTATSPEQ--LSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSS 1222
+A YT S EQ L+ +G +++V KK D WW G + K G FP++YV++ S
Sbjct: 1003 IAMYTYESSEQGDLTFQQGDVILVTKK-DGDWWTGTVGDKA-----GVFPSNYVRLKDSE 1056
Query: 1223 GRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDP-A 1281
G + T L K + I +V+A YTA ++L+ +I + R ++P
Sbjct: 1057 GSGTAGKTGSLGKKPE-------IAQVIA--SYTATGPEQLTLAPGQLILI--RKKNPGG 1105
Query: 1282 WWQGEL--RG---MVGLFPSNYVTKLVN 1304
WW+GEL RG +G FP+NYV KL+N
Sbjct: 1106 WWEGELQARGKKRQIGWFPANYV-KLLN 1132
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/90 (31%), Positives = 52/90 (57%)
Query: 633 QCQLEWEKKRTRELEALRSEEQSKVLSLKAKCQSLSAQLGAESVRCSTLAASIRDTRTAV 692
Q QLEWE+ R +EL R++EQ ++ LKAK ++L +L A + + L ++D R +
Sbjct: 444 QRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRL 503
Query: 693 AADKRTIDGMRSDRDSSMAEMQQLKARVKE 722
++ I+ R+ +AE+ L+ +++E
Sbjct: 504 TTQRQEIESTNKSRELRIAEITHLQQQLQE 533
Score = 52.8 bits (121), Expect = 8e-06
Identities = 24/54 (44%), Positives = 36/54 (66%), Gaps = 3/54 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQ--DPAWWQGELRGMVGLFPSNYVTKL 1302
ALYP+ +++ DE++ + DI+ V D SQ +P W GEL+G G FP+NY K+
Sbjct: 747 ALYPFESRSHDEITIQPGDIVMV-DESQTGEPGWLGGELKGKTGWFPANYAEKI 799
Score = 52.0 bits (119), Expect = 1e-05
Identities = 24/54 (44%), Positives = 36/54 (66%), Gaps = 3/54 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
ALYP+ A+ + L+F K+D+I V + Q WW GE++G G FP +YV KL++
Sbjct: 915 ALYPWRAKKDNHLNFNKNDVITVLE--QQDMWWFGEVQGQKGWFPKSYV-KLIS 965
Score = 49.2 bits (112), Expect = 1e-04
Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 6/81 (7%)
Query: 887 WRCVYPFVGRSADELSVQPGDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESYVE-----D 941
+R +YPF RS DE+++QPGD IV +G++GWFP +Y E +
Sbjct: 745 YRALYPFESRSHDEITIQPGD-IVMVDESQTGEPGWLGGELKGKTGWFPANYAEKIPENE 803
Query: 942 LNAPTAFVTEVIETLEPKTQL 962
+ AP VT+ PK L
Sbjct: 804 VPAPVKPVTDSTSAPAPKLAL 824
Score = 33.9 bits (74), Expect = 3.8
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 466 RRENMARGQAELERRRTQLADAQMKEKVRGRGLNQSQ 502
+REN RG ELE+RR L + Q KE+ R L +++
Sbjct: 354 KRENFERGNLELEKRRQALLEQQRKEQERLAQLERAE 390
Score = 33.1 bits (72), Expect = 6.7
Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 6/94 (6%)
Query: 878 GGEGPQPPRWRCVYPFVGRSADELSVQPGDLIVXXXXXXXX--XXXXXXXXXRGQSGWFP 935
G G +P + + + ++L++ PG LI+ + Q GWFP
Sbjct: 1065 GSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFP 1124
Query: 936 ESYVEDLNAPTAFVTEVIETLEPK-TQLEGIAEV 968
+YV+ LN T+ +T T PK T L + +V
Sbjct: 1125 ANYVKLLNPGTSKIT---PTEPPKSTALAAVCQV 1155
>DQ679756-1|ABG74697.1| 1178|Homo sapiens intersectin 1 short form
variant 2 protein.
Length = 1178
Score = 179 bits (435), Expect = 7e-44
Identities = 104/304 (34%), Positives = 151/304 (49%), Gaps = 24/304 (7%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIFPSNYVSREAAPAATSXXX 1065
A YP+ + + L F + I V+ + WW G + + G FP +YV + P S
Sbjct: 878 ALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISGPIRKSTSM 937
Query: 1066 XXXXXXXXXXXXXXXXXXXTSPPNTTPPIPASQLI----WTSNE---LAYTSVTFLLAQD 1118
+ P P + + I + S+E L + +L
Sbjct: 938 DSGSSESPASLKR------VASPAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTK 991
Query: 1119 QKS---STPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRRKHEIVQALASYTATSPEQ 1175
+ + + + + +G+ G+ K EI Q +ASYTAT PEQ
Sbjct: 992 KDGDWWTGTVGDKAGVFPSNYVRLKDSEGSGTAGKTGSLGK-KPEIAQVIASYTATGPEQ 1050
Query: 1176 LSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRTTPVLSS 1235
L+L GQL+++RKK GWWEGELQA+G+ RQ+GWFPA+YVK+L + + TP
Sbjct: 1051 LTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLNPG---TSKITPTEPP 1107
Query: 1236 KMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFP 1295
K AL + +V+ +Y YTAQN DEL+F K II V ++ +DP WW+GE+ G VGLFP
Sbjct: 1108 KSTAL---AAVCQVIGMYDYTAQNDDELAFNKGQIINVLNK-EDPDWWKGEVNGQVGLFP 1163
Query: 1296 SNYV 1299
SNYV
Sbjct: 1164 SNYV 1167
Score = 123 bits (297), Expect = 4e-27
Identities = 55/97 (56%), Positives = 70/97 (72%)
Query: 350 PPPMEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLD 409
PP EW VPQ +LKY QLFN+ D+ +G +G QAR+I++QS LPQ LA IW L+D+D
Sbjct: 173 PPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDID 232
Query: 410 ADGKLGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
DGKL EEF+LAM+L + A G+P+P LPPE IPP
Sbjct: 233 QDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPP 269
Score = 106 bits (254), Expect = 6e-22
Identities = 47/88 (53%), Positives = 61/88 (69%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGK 63
D W I E AK + F +L P++G +TG+QA+ F QS LP PVL QIW+LAD N DG+
Sbjct: 13 DIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGR 72
Query: 64 LDLKEFSIACKIINLKLRGLEVPKMLPP 91
+D EFSIA K+I LKL+G ++P LPP
Sbjct: 73 MDQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 105 bits (253), Expect = 8e-22
Identities = 83/291 (28%), Positives = 126/291 (43%), Gaps = 34/291 (11%)
Query: 928 RGQSGWFPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDP 987
+GQ GWFP+SYV+ ++ P + T ++ +S+ +L V P
Sbjct: 913 QGQKGWFPKSYVKLISGP----------IRKSTSMDS--------GSSESPASLKRVASP 954
Query: 988 GRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIF 1047
++PV GE +IA Y Y SSE GDL F+ G+ I V ++DGDWWTG +G + G+F
Sbjct: 955 A---AKPVV---SGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTVGDKAGVF 1008
Query: 1048 PSNYVSREAAPAATSXXXXXXXXXXXXXXXXXXXXXXTSPPNTTPPIPASQLIWTSNELA 1107
PSNYV + + + + T P T LI N
Sbjct: 1009 PSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGG 1068
Query: 1108 YTSVTFLLAQDQKSSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRRKHEIVQALAS 1167
+ L A+ +K I A + + + I +
Sbjct: 1069 WWEGE-LQARGKKRQ--IGWFPANYVKLLNPGTSKITPTEPPKSTALAAVCQVI--GMYD 1123
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKV 1218
YTA + ++L+ KGQ++ V K D WW+GE+ N QVG FP++YVK+
Sbjct: 1124 YTAQNDDELAFNKGQIINVLNKEDPDWWKGEV-----NGQVGLFPSNYVKL 1169
Score = 94.7 bits (225), Expect = 2e-18
Identities = 92/348 (26%), Positives = 146/348 (41%), Gaps = 41/348 (11%)
Query: 980 ALPAVVDPGRTVSE---PVSVEDDGE--FYIASYPYSSSEPGDLVFEAGERIEVVR-RDG 1033
A PAV P T + +S +++ + +Y A YP+ S ++ + G+ + V + G
Sbjct: 679 AKPAVQAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMVDESQTG 738
Query: 1034 D--WWTGRIGARTGIFPSNYVSR---EAAPAATSXXXXXXXXXXXXXXXXXX---XXXXT 1085
+ W G + +TG FP+NY + PA +
Sbjct: 739 EPGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTDSTSAPAPKLALRETPAPLAVTS 798
Query: 1086 SPPNTTPPIPAS-QLIW--TSNELAYTSVTFLLAQDQKSSTPISSEVAMITDXXXXXXXX 1142
S P+TTP A W ++NE T A + P + ++
Sbjct: 799 SEPSTTPNNWADFSSTWPTSTNEKPETDNWDAWAAQPSLTVPSAGQLRQ-----RSAFTP 853
Query: 1143 XXXXDSGRDSVTGR-RKHEIVQALASYT--ATSPEQLSLMKGQLLVVRKKADSGWWEGEL 1199
S V G+ K E +QA A Y A L+ K ++ V ++ D WW GE+
Sbjct: 854 ATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDM-WWFGEV 912
Query: 1200 QAKGRNRQVGWFPASYVKVL-----QSSGRTSGRTTPVLSSKMDALPTETVI---DKVVA 1251
Q Q GWFP SYVK++ +S+ SG + S K A P + ++ +A
Sbjct: 913 QG-----QKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKPVVSGEEFIA 967
Query: 1252 LYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+Y Y + +L+F++ D+I VT + D WW G + G+FPSNYV
Sbjct: 968 MYTYESSEQGDLTFQQGDVILVTKKDGD--WWTGTVGDKAGVFPSNYV 1013
Score = 71.3 bits (167), Expect = 2e-11
Identities = 36/87 (41%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 355 WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKL 414
W + ++ K+ Q F++ + +G +G QAR+ QS LPQ LAQIWALAD++ DG++
Sbjct: 15 WAITVEERAKHDQQFHSL-KPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRM 73
Query: 415 GCEEFVLAMYLCEKATQGEPVPARLPP 441
EF +AM L + QG +P+ LPP
Sbjct: 74 DQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 69.7 bits (163), Expect = 6e-11
Identities = 32/90 (35%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F + ++G+LTG QA+ ++QS LP L IW+L+D + DGKL
Sbjct: 178 WAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKL 237
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A +I++ + G +P +LPP I
Sbjct: 238 TAEEFILAMHLIDVAMSGQPLPPVLPPEYI 267
Score = 64.9 bits (151), Expect = 2e-09
Identities = 52/148 (35%), Positives = 78/148 (52%), Gaps = 26/148 (17%)
Query: 1165 LASYTATSPEQ--LSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSS 1222
+A YT S EQ L+ +G +++V KK D WW G + K G FP++YV++ S
Sbjct: 966 IAMYTYESSEQGDLTFQQGDVILVTKK-DGDWWTGTVGDKA-----GVFPSNYVRLKDSE 1019
Query: 1223 GRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDP-A 1281
G + T L K + I +V+A YTA ++L+ +I + R ++P
Sbjct: 1020 GSGTAGKTGSLGKKPE-------IAQVIA--SYTATGPEQLTLAPGQLILI--RKKNPGG 1068
Query: 1282 WWQGEL--RG---MVGLFPSNYVTKLVN 1304
WW+GEL RG +G FP+NYV KL+N
Sbjct: 1069 WWEGELQARGKKRQIGWFPANYV-KLLN 1095
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/90 (31%), Positives = 52/90 (57%)
Query: 633 QCQLEWEKKRTRELEALRSEEQSKVLSLKAKCQSLSAQLGAESVRCSTLAASIRDTRTAV 692
Q QLEWE+ R +EL R++EQ ++ LKAK ++L +L A + + L ++D R +
Sbjct: 407 QRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRL 466
Query: 693 AADKRTIDGMRSDRDSSMAEMQQLKARVKE 722
++ I+ R+ +AE+ L+ +++E
Sbjct: 467 TTQRQEIESTNKSRELRIAEITHLQQQLQE 496
Score = 52.8 bits (121), Expect = 8e-06
Identities = 24/54 (44%), Positives = 36/54 (66%), Gaps = 3/54 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQ--DPAWWQGELRGMVGLFPSNYVTKL 1302
ALYP+ +++ DE++ + DI+ V D SQ +P W GEL+G G FP+NY K+
Sbjct: 710 ALYPFESRSHDEITIQPGDIVMV-DESQTGEPGWLGGELKGKTGWFPANYAEKI 762
Score = 52.0 bits (119), Expect = 1e-05
Identities = 24/54 (44%), Positives = 36/54 (66%), Gaps = 3/54 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
ALYP+ A+ + L+F K+D+I V + Q WW GE++G G FP +YV KL++
Sbjct: 878 ALYPWRAKKDNHLNFNKNDVITVLE--QQDMWWFGEVQGQKGWFPKSYV-KLIS 928
Score = 49.2 bits (112), Expect = 1e-04
Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 6/81 (7%)
Query: 887 WRCVYPFVGRSADELSVQPGDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESYVE-----D 941
+R +YPF RS DE+++QPGD IV +G++GWFP +Y E +
Sbjct: 708 YRALYPFESRSHDEITIQPGD-IVMVDESQTGEPGWLGGELKGKTGWFPANYAEKIPENE 766
Query: 942 LNAPTAFVTEVIETLEPKTQL 962
+ AP VT+ PK L
Sbjct: 767 VPAPVKPVTDSTSAPAPKLAL 787
Score = 33.9 bits (74), Expect = 3.8
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 466 RRENMARGQAELERRRTQLADAQMKEKVRGRGLNQSQ 502
+REN RG ELE+RR L + Q KE+ R L +++
Sbjct: 317 KRENFERGNLELEKRRQALLEQQRKEQERLAQLERAE 353
Score = 33.1 bits (72), Expect = 6.7
Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 6/94 (6%)
Query: 878 GGEGPQPPRWRCVYPFVGRSADELSVQPGDLIVXXXXXXXX--XXXXXXXXXRGQSGWFP 935
G G +P + + + ++L++ PG LI+ + Q GWFP
Sbjct: 1028 GSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFP 1087
Query: 936 ESYVEDLNAPTAFVTEVIETLEPK-TQLEGIAEV 968
+YV+ LN T+ +T T PK T L + +V
Sbjct: 1088 ANYVKLLNPGTSKIT---PTEPPKSTALAAVCQV 1118
>AF064244-1|AAC78611.1| 1721|Homo sapiens intersectin long form
protein.
Length = 1721
Score = 179 bits (435), Expect = 7e-44
Identities = 104/304 (34%), Positives = 151/304 (49%), Gaps = 24/304 (7%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIFPSNYVSREAAPAATSXXX 1065
A YP+ + + L F + I V+ + WW G + + G FP +YV + P S
Sbjct: 920 ALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISGPIRKSTSM 979
Query: 1066 XXXXXXXXXXXXXXXXXXXTSPPNTTPPIPASQLI----WTSNE---LAYTSVTFLLAQD 1118
+ P P + + I + S+E L + +L
Sbjct: 980 DSGSSESPASLKR------VASPAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTK 1033
Query: 1119 QKS---STPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRRKHEIVQALASYTATSPEQ 1175
+ + + + + +G+ G+ K EI Q +ASYTAT PEQ
Sbjct: 1034 KDGDWWTGTVGDKAGVFPSNYVRLKDSEGSGTAGKTGSLGK-KPEIAQVIASYTATGPEQ 1092
Query: 1176 LSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRTTPVLSS 1235
L+L GQL+++RKK GWWEGELQA+G+ RQ+GWFPA+YVK+L + + TP
Sbjct: 1093 LTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLNPG---TSKITPTEPP 1149
Query: 1236 KMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFP 1295
K AL + +V+ +Y YTAQN DEL+F K II V ++ +DP WW+GE+ G VGLFP
Sbjct: 1150 KSTAL---AAVCQVIGMYDYTAQNDDELAFNKGQIINVLNK-EDPDWWKGEVNGQVGLFP 1205
Query: 1296 SNYV 1299
SNYV
Sbjct: 1206 SNYV 1209
Score = 133 bits (322), Expect = 3e-30
Identities = 82/211 (38%), Positives = 110/211 (52%), Gaps = 10/211 (4%)
Query: 242 PIMSSQPLI--SASTISAQPLGTMQPLIGTAPPIMGATQALIQSPPLSGPQQPAPVTAAS 299
P+M QP+ SA + +M PL AP MG+ + SP L A V +
Sbjct: 100 PVMKQQPVAISSAPPFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLA 159
Query: 300 FGGXXXXXXXXXXXXGQPVTSTPIAALNKEVISKPGSVVTSP---EVPMGVMSPPPM-EW 355
G P + P ++ S PGS + + V S PP+ EW
Sbjct: 160 NGAPPVIQPLPAFA--HPAATLPKSSSFSR--SGPGSQLNTKLQKAQSFDVASVPPVAEW 215
Query: 356 GVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLG 415
VPQ +LKY QLFN+ D+ +G +G QAR+I++QS LPQ LA IW L+D+D DGKL
Sbjct: 216 AVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLT 275
Query: 416 CEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
EEF+LAM+L + A G+P+P LPPE IPP
Sbjct: 276 AEEFILAMHLIDVAMSGQPLPPVLPPEYIPP 306
Score = 106 bits (254), Expect = 6e-22
Identities = 47/88 (53%), Positives = 61/88 (69%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGK 63
D W I E AK + F +L P++G +TG+QA+ F QS LP PVL QIW+LAD N DG+
Sbjct: 13 DIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGR 72
Query: 64 LDLKEFSIACKIINLKLRGLEVPKMLPP 91
+D EFSIA K+I LKL+G ++P LPP
Sbjct: 73 MDQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 105 bits (253), Expect = 8e-22
Identities = 83/291 (28%), Positives = 126/291 (43%), Gaps = 34/291 (11%)
Query: 928 RGQSGWFPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDP 987
+GQ GWFP+SYV+ ++ P + T ++ +S+ +L V P
Sbjct: 955 QGQKGWFPKSYVKLISGP----------IRKSTSMDS--------GSSESPASLKRVASP 996
Query: 988 GRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIF 1047
++PV GE +IA Y Y SSE GDL F+ G+ I V ++DGDWWTG +G + G+F
Sbjct: 997 A---AKPVV---SGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTVGDKAGVF 1050
Query: 1048 PSNYVSREAAPAATSXXXXXXXXXXXXXXXXXXXXXXTSPPNTTPPIPASQLIWTSNELA 1107
PSNYV + + + + T P T LI N
Sbjct: 1051 PSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGG 1110
Query: 1108 YTSVTFLLAQDQKSSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRRKHEIVQALAS 1167
+ L A+ +K I A + + + I +
Sbjct: 1111 WWEGE-LQARGKKRQ--IGWFPANYVKLLNPGTSKITPTEPPKSTALAAVCQVI--GMYD 1165
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKV 1218
YTA + ++L+ KGQ++ V K D WW+GE+ N QVG FP++YVK+
Sbjct: 1166 YTAQNDDELAFNKGQIINVLNKEDPDWWKGEV-----NGQVGLFPSNYVKL 1211
Score = 96.7 bits (230), Expect = 5e-19
Identities = 95/353 (26%), Positives = 148/353 (41%), Gaps = 46/353 (13%)
Query: 980 ALPAVVDPGRTVSE---PVSVEDDGE--FYIASYPYSSS-------EPGDLVFEAGERIE 1027
A PAV P T + +S +++ + +Y A YP+ S +PGD+V GE ++
Sbjct: 716 AKPAVQAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMVKGEWVD 775
Query: 1028 VVRR-DGDWWTGRIGARTGIFPSNYVSR---EAAPAATSXXXXXXXXXXXXXXXXXX--- 1080
+ + W G + +TG FP+NY + PA
Sbjct: 776 ESQTGEPGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTDSTSAPAPKLALRETPAP 835
Query: 1081 XXXXTSPPNTTPPIPAS-QLIW--TSNELAYTSVTFLLAQDQKSSTPISSEVAMITDXXX 1137
+S P+TTP A W ++NE T A + P + ++
Sbjct: 836 LAVTSSEPSTTPNNWADFSSTWPTSTNEKPETDNWDAWAAQPSLTVPSAGQLRQ-----R 890
Query: 1138 XXXXXXXXXDSGRDSVTGR-RKHEIVQALASYT--ATSPEQLSLMKGQLLVVRKKADSGW 1194
S V G+ K E +QA A Y A L+ K ++ V ++ D W
Sbjct: 891 SAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDM-W 949
Query: 1195 WEGELQAKGRNRQVGWFPASYVKVL-----QSSGRTSGRTTPVLSSKMDALPTETVI--- 1246
W GE+Q Q GWFP SYVK++ +S+ SG + S K A P +
Sbjct: 950 WFGEVQG-----QKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKPVVSG 1004
Query: 1247 DKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
++ +A+Y Y + +L+F++ D+I VT + D WW G + G+FPSNYV
Sbjct: 1005 EEFIAMYTYESSEQGDLTFQQGDVILVTKKDGD--WWTGTVGDKAGVFPSNYV 1055
Score = 71.3 bits (167), Expect = 2e-11
Identities = 36/87 (41%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 355 WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKL 414
W + ++ K+ Q F++ + +G +G QAR+ QS LPQ LAQIWALAD++ DG++
Sbjct: 15 WAITVEERAKHDQQFHSL-KPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRM 73
Query: 415 GCEEFVLAMYLCEKATQGEPVPARLPP 441
EF +AM L + QG +P+ LPP
Sbjct: 74 DQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 69.7 bits (163), Expect = 6e-11
Identities = 32/90 (35%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F + ++G+LTG QA+ ++QS LP L IW+L+D + DGKL
Sbjct: 215 WAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKL 274
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A +I++ + G +P +LPP I
Sbjct: 275 TAEEFILAMHLIDVAMSGQPLPPVLPPEYI 304
Score = 64.9 bits (151), Expect = 2e-09
Identities = 52/148 (35%), Positives = 78/148 (52%), Gaps = 26/148 (17%)
Query: 1165 LASYTATSPEQ--LSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSS 1222
+A YT S EQ L+ +G +++V KK D WW G + K G FP++YV++ S
Sbjct: 1008 IAMYTYESSEQGDLTFQQGDVILVTKK-DGDWWTGTVGDKA-----GVFPSNYVRLKDSE 1061
Query: 1223 GRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDP-A 1281
G + T L K + I +V+A YTA ++L+ +I + R ++P
Sbjct: 1062 GSGTAGKTGSLGKKPE-------IAQVIA--SYTATGPEQLTLAPGQLILI--RKKNPGG 1110
Query: 1282 WWQGEL--RG---MVGLFPSNYVTKLVN 1304
WW+GEL RG +G FP+NYV KL+N
Sbjct: 1111 WWEGELQARGKKRQIGWFPANYV-KLLN 1137
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/90 (31%), Positives = 52/90 (57%)
Query: 633 QCQLEWEKKRTRELEALRSEEQSKVLSLKAKCQSLSAQLGAESVRCSTLAASIRDTRTAV 692
Q QLEWE+ R +EL R++EQ ++ LKAK ++L +L A + + L ++D R +
Sbjct: 444 QRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRL 503
Query: 693 AADKRTIDGMRSDRDSSMAEMQQLKARVKE 722
++ I+ R+ +AE+ L+ +++E
Sbjct: 504 TTQRQEIESTNKSRELRIAEITHLQQQLQE 533
Score = 52.0 bits (119), Expect = 1e-05
Identities = 24/54 (44%), Positives = 36/54 (66%), Gaps = 3/54 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
ALYP+ A+ + L+F K+D+I V + Q WW GE++G G FP +YV KL++
Sbjct: 920 ALYPWRAKKDNHLNFNKNDVITVLE--QQDMWWFGEVQGQKGWFPKSYV-KLIS 970
Score = 50.4 bits (115), Expect = 4e-05
Identities = 24/58 (41%), Positives = 36/58 (62%), Gaps = 6/58 (10%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAV----TDRSQ--DPAWWQGELRGMVGLFPSNYVTKL 1302
ALYP+ +++ DE++ + DI+ V D SQ +P W GEL+G G FP+NY K+
Sbjct: 747 ALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804
Score = 46.4 bits (105), Expect = 7e-04
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 9/85 (10%)
Query: 887 WRCVYPFVGRSADELSVQPGDLIVXXXXXXXXXXXX----XXXXXRGQSGWFPESYVE-- 940
+R +YPF RS DE+++QPGD+++ +G++GWFP +Y E
Sbjct: 745 YRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804
Query: 941 ---DLNAPTAFVTEVIETLEPKTQL 962
++ AP VT+ PK L
Sbjct: 805 PENEVPAPVKPVTDSTSAPAPKLAL 829
Score = 33.9 bits (74), Expect = 3.8
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 466 RRENMARGQAELERRRTQLADAQMKEKVRGRGLNQSQ 502
+REN RG ELE+RR L + Q KE+ R L +++
Sbjct: 354 KRENFERGNLELEKRRQALLEQQRKEQERLAQLERAE 390
Score = 33.1 bits (72), Expect = 6.7
Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 6/94 (6%)
Query: 878 GGEGPQPPRWRCVYPFVGRSADELSVQPGDLIVXXXXXXXX--XXXXXXXXXRGQSGWFP 935
G G +P + + + ++L++ PG LI+ + Q GWFP
Sbjct: 1070 GSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFP 1129
Query: 936 ESYVEDLNAPTAFVTEVIETLEPK-TQLEGIAEV 968
+YV+ LN T+ +T T PK T L + +V
Sbjct: 1130 ANYVKLLNPGTSKIT---PTEPPKSTALAAVCQV 1160
>AF064243-1|AAC78610.1| 1220|Homo sapiens intersectin short form
protein.
Length = 1220
Score = 179 bits (435), Expect = 7e-44
Identities = 104/304 (34%), Positives = 151/304 (49%), Gaps = 24/304 (7%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIFPSNYVSREAAPAATSXXX 1065
A YP+ + + L F + I V+ + WW G + + G FP +YV + P S
Sbjct: 920 ALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISGPIRKSTSM 979
Query: 1066 XXXXXXXXXXXXXXXXXXXTSPPNTTPPIPASQLI----WTSNE---LAYTSVTFLLAQD 1118
+ P P + + I + S+E L + +L
Sbjct: 980 DSGSSESPASLKR------VASPAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTK 1033
Query: 1119 QKS---STPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRRKHEIVQALASYTATSPEQ 1175
+ + + + + +G+ G+ K EI Q +ASYTAT PEQ
Sbjct: 1034 KDGDWWTGTVGDKAGVFPSNYVRLKDSEGSGTAGKTGSLGK-KPEIAQVIASYTATGPEQ 1092
Query: 1176 LSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRTTPVLSS 1235
L+L GQL+++RKK GWWEGELQA+G+ RQ+GWFPA+YVK+L + + TP
Sbjct: 1093 LTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLNPG---TSKITPTEPP 1149
Query: 1236 KMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFP 1295
K AL + +V+ +Y YTAQN DEL+F K II V ++ +DP WW+GE+ G VGLFP
Sbjct: 1150 KSTAL---AAVCQVIGMYDYTAQNDDELAFNKGQIINVLNK-EDPDWWKGEVNGQVGLFP 1205
Query: 1296 SNYV 1299
SNYV
Sbjct: 1206 SNYV 1209
Score = 133 bits (322), Expect = 3e-30
Identities = 82/211 (38%), Positives = 110/211 (52%), Gaps = 10/211 (4%)
Query: 242 PIMSSQPLI--SASTISAQPLGTMQPLIGTAPPIMGATQALIQSPPLSGPQQPAPVTAAS 299
P+M QP+ SA + +M PL AP MG+ + SP L A V +
Sbjct: 100 PVMKQQPVAISSAPPFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLA 159
Query: 300 FGGXXXXXXXXXXXXGQPVTSTPIAALNKEVISKPGSVVTSP---EVPMGVMSPPPM-EW 355
G P + P ++ S PGS + + V S PP+ EW
Sbjct: 160 NGAPPVIQPLPAFA--HPAATLPKSSSFSR--SGPGSQLNTKLQKAQSFDVASVPPVAEW 215
Query: 356 GVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLG 415
VPQ +LKY QLFN+ D+ +G +G QAR+I++QS LPQ LA IW L+D+D DGKL
Sbjct: 216 AVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLT 275
Query: 416 CEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
EEF+LAM+L + A G+P+P LPPE IPP
Sbjct: 276 AEEFILAMHLIDVAMSGQPLPPVLPPEYIPP 306
Score = 106 bits (254), Expect = 6e-22
Identities = 47/88 (53%), Positives = 61/88 (69%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGK 63
D W I E AK + F +L P++G +TG+QA+ F QS LP PVL QIW+LAD N DG+
Sbjct: 13 DIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGR 72
Query: 64 LDLKEFSIACKIINLKLRGLEVPKMLPP 91
+D EFSIA K+I LKL+G ++P LPP
Sbjct: 73 MDQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 105 bits (253), Expect = 8e-22
Identities = 83/291 (28%), Positives = 126/291 (43%), Gaps = 34/291 (11%)
Query: 928 RGQSGWFPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDP 987
+GQ GWFP+SYV+ ++ P + T ++ +S+ +L V P
Sbjct: 955 QGQKGWFPKSYVKLISGP----------IRKSTSMDS--------GSSESPASLKRVASP 996
Query: 988 GRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIF 1047
++PV GE +IA Y Y SSE GDL F+ G+ I V ++DGDWWTG +G + G+F
Sbjct: 997 A---AKPVV---SGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTVGDKAGVF 1050
Query: 1048 PSNYVSREAAPAATSXXXXXXXXXXXXXXXXXXXXXXTSPPNTTPPIPASQLIWTSNELA 1107
PSNYV + + + + T P T LI N
Sbjct: 1051 PSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGG 1110
Query: 1108 YTSVTFLLAQDQKSSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRRKHEIVQALAS 1167
+ L A+ +K I A + + + I +
Sbjct: 1111 WWEGE-LQARGKKRQ--IGWFPANYVKLLNPGTSKITPTEPPKSTALAAVCQVI--GMYD 1165
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKV 1218
YTA + ++L+ KGQ++ V K D WW+GE+ N QVG FP++YVK+
Sbjct: 1166 YTAQNDDELAFNKGQIINVLNKEDPDWWKGEV-----NGQVGLFPSNYVKL 1211
Score = 96.7 bits (230), Expect = 5e-19
Identities = 95/353 (26%), Positives = 148/353 (41%), Gaps = 46/353 (13%)
Query: 980 ALPAVVDPGRTVSE---PVSVEDDGE--FYIASYPYSSS-------EPGDLVFEAGERIE 1027
A PAV P T + +S +++ + +Y A YP+ S +PGD+V GE ++
Sbjct: 716 AKPAVQAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMVKGEWVD 775
Query: 1028 VVRR-DGDWWTGRIGARTGIFPSNYVSR---EAAPAATSXXXXXXXXXXXXXXXXXX--- 1080
+ + W G + +TG FP+NY + PA
Sbjct: 776 ESQTGEPGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTDSTSAPAPKLALRETPAP 835
Query: 1081 XXXXTSPPNTTPPIPAS-QLIW--TSNELAYTSVTFLLAQDQKSSTPISSEVAMITDXXX 1137
+S P+TTP A W ++NE T A + P + ++
Sbjct: 836 LAVTSSEPSTTPNNWADFSSTWPTSTNEKPETDNWDAWAAQPSLTVPSAGQLRQ-----R 890
Query: 1138 XXXXXXXXXDSGRDSVTGR-RKHEIVQALASYT--ATSPEQLSLMKGQLLVVRKKADSGW 1194
S V G+ K E +QA A Y A L+ K ++ V ++ D W
Sbjct: 891 SAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDM-W 949
Query: 1195 WEGELQAKGRNRQVGWFPASYVKVL-----QSSGRTSGRTTPVLSSKMDALPTETVI--- 1246
W GE+Q Q GWFP SYVK++ +S+ SG + S K A P +
Sbjct: 950 WFGEVQG-----QKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKPVVSG 1004
Query: 1247 DKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
++ +A+Y Y + +L+F++ D+I VT + D WW G + G+FPSNYV
Sbjct: 1005 EEFIAMYTYESSEQGDLTFQQGDVILVTKKDGD--WWTGTVGDKAGVFPSNYV 1055
Score = 71.3 bits (167), Expect = 2e-11
Identities = 36/87 (41%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 355 WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKL 414
W + ++ K+ Q F++ + +G +G QAR+ QS LPQ LAQIWALAD++ DG++
Sbjct: 15 WAITVEERAKHDQQFHSL-KPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRM 73
Query: 415 GCEEFVLAMYLCEKATQGEPVPARLPP 441
EF +AM L + QG +P+ LPP
Sbjct: 74 DQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 69.7 bits (163), Expect = 6e-11
Identities = 32/90 (35%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F + ++G+LTG QA+ ++QS LP L IW+L+D + DGKL
Sbjct: 215 WAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKL 274
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A +I++ + G +P +LPP I
Sbjct: 275 TAEEFILAMHLIDVAMSGQPLPPVLPPEYI 304
Score = 64.9 bits (151), Expect = 2e-09
Identities = 52/148 (35%), Positives = 78/148 (52%), Gaps = 26/148 (17%)
Query: 1165 LASYTATSPEQ--LSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSS 1222
+A YT S EQ L+ +G +++V KK D WW G + K G FP++YV++ S
Sbjct: 1008 IAMYTYESSEQGDLTFQQGDVILVTKK-DGDWWTGTVGDKA-----GVFPSNYVRLKDSE 1061
Query: 1223 GRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDP-A 1281
G + T L K + I +V+A YTA ++L+ +I + R ++P
Sbjct: 1062 GSGTAGKTGSLGKKPE-------IAQVIA--SYTATGPEQLTLAPGQLILI--RKKNPGG 1110
Query: 1282 WWQGEL--RG---MVGLFPSNYVTKLVN 1304
WW+GEL RG +G FP+NYV KL+N
Sbjct: 1111 WWEGELQARGKKRQIGWFPANYV-KLLN 1137
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/90 (31%), Positives = 52/90 (57%)
Query: 633 QCQLEWEKKRTRELEALRSEEQSKVLSLKAKCQSLSAQLGAESVRCSTLAASIRDTRTAV 692
Q QLEWE+ R +EL R++EQ ++ LKAK ++L +L A + + L ++D R +
Sbjct: 444 QRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRL 503
Query: 693 AADKRTIDGMRSDRDSSMAEMQQLKARVKE 722
++ I+ R+ +AE+ L+ +++E
Sbjct: 504 TTQRQEIESTNKSRELRIAEITHLQQQLQE 533
Score = 52.0 bits (119), Expect = 1e-05
Identities = 24/54 (44%), Positives = 36/54 (66%), Gaps = 3/54 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
ALYP+ A+ + L+F K+D+I V + Q WW GE++G G FP +YV KL++
Sbjct: 920 ALYPWRAKKDNHLNFNKNDVITVLE--QQDMWWFGEVQGQKGWFPKSYV-KLIS 970
Score = 50.4 bits (115), Expect = 4e-05
Identities = 24/58 (41%), Positives = 36/58 (62%), Gaps = 6/58 (10%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAV----TDRSQ--DPAWWQGELRGMVGLFPSNYVTKL 1302
ALYP+ +++ DE++ + DI+ V D SQ +P W GEL+G G FP+NY K+
Sbjct: 747 ALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804
Score = 46.4 bits (105), Expect = 7e-04
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 9/85 (10%)
Query: 887 WRCVYPFVGRSADELSVQPGDLIVXXXXXXXXXXXX----XXXXXRGQSGWFPESYVE-- 940
+R +YPF RS DE+++QPGD+++ +G++GWFP +Y E
Sbjct: 745 YRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804
Query: 941 ---DLNAPTAFVTEVIETLEPKTQL 962
++ AP VT+ PK L
Sbjct: 805 PENEVPAPVKPVTDSTSAPAPKLAL 829
Score = 33.9 bits (74), Expect = 3.8
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 466 RRENMARGQAELERRRTQLADAQMKEKVRGRGLNQSQ 502
+REN RG ELE+RR L + Q KE+ R L +++
Sbjct: 354 KRENFERGNLELEKRRQALLEQQRKEQERLAQLERAE 390
Score = 33.1 bits (72), Expect = 6.7
Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 6/94 (6%)
Query: 878 GGEGPQPPRWRCVYPFVGRSADELSVQPGDLIVXXXXXXXX--XXXXXXXXXRGQSGWFP 935
G G +P + + + ++L++ PG LI+ + Q GWFP
Sbjct: 1070 GSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFP 1129
Query: 936 ESYVEDLNAPTAFVTEVIETLEPK-TQLEGIAEV 968
+YV+ LN T+ +T T PK T L + +V
Sbjct: 1130 ANYVKLLNPGTSKIT---PTEPPKSTALAAVCQV 1160
>BC116185-1|AAI16186.1| 1716|Homo sapiens ITSN1 protein protein.
Length = 1716
Score = 177 bits (432), Expect = 2e-43
Identities = 105/304 (34%), Positives = 153/304 (50%), Gaps = 24/304 (7%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIFPSNYVSREAAPAATSXXX 1065
A YP+ + + L F + I V+ + WW G + + G FP +YV + P S
Sbjct: 915 ALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISGPIRKSTSM 974
Query: 1066 XXXXXXXXXXXXXXXXXXXTSPPNTTPPIPASQLI----WTSNE---LAYTSVTFLLAQD 1118
+ P P + + I + S+E L + +L
Sbjct: 975 DSGSSESPASLKR------VASPAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTK 1028
Query: 1119 QKS---STPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRRKHEIVQALASYTATSPEQ 1175
+ + + + + +G+ G+ K EI Q +ASYTAT PEQ
Sbjct: 1029 KDGDWWTGTVGDKAGVFPSNYVRLKDSEGSGTAGKTGSLGK-KPEIAQVIASYTATGPEQ 1087
Query: 1176 LSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRTTPVLSS 1235
L+L GQL++++KK GWWEGELQA+G+ RQ+GWFPA+YVK+L S G + + TP
Sbjct: 1088 LTLAPGQLILIQKKNPGGWWEGELQARGKKRQIGWFPANYVKLL-SPG--TSKITPTEPP 1144
Query: 1236 KMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFP 1295
K AL + +V+ +Y YTAQN DEL+F K II V ++ +DP WW+GE+ G VGLFP
Sbjct: 1145 KSTAL---AAVCQVIGMYDYTAQNDDELAFNKGQIINVLNK-EDPDWWKGEVNGQVGLFP 1200
Query: 1296 SNYV 1299
SNYV
Sbjct: 1201 SNYV 1204
Score = 134 bits (323), Expect = 3e-30
Identities = 82/211 (38%), Positives = 110/211 (52%), Gaps = 10/211 (4%)
Query: 242 PIMSSQPLI--SASTISAQPLGTMQPLIGTAPPIMGATQALIQSPPLSGPQQPAPVTAAS 299
P+M QP+ SA + +M PL AP MG+ + SP L A V +
Sbjct: 100 PVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLA 159
Query: 300 FGGXXXXXXXXXXXXGQPVTSTPIAALNKEVISKPGSVVTSP---EVPMGVMSPPPM-EW 355
G P + P ++ S PGS + + V S PP+ EW
Sbjct: 160 NGAPPVIQPLPAFA--HPAATLPKSSSFSR--SGPGSQLNTKLQKAQSFDVASVPPVAEW 215
Query: 356 GVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLG 415
VPQ +LKY QLFN+ D+ +G +G QAR+I++QS LPQ LA IW L+D+D DGKL
Sbjct: 216 AVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLT 275
Query: 416 CEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
EEF+LAM+L + A G+P+P LPPE IPP
Sbjct: 276 AEEFILAMHLIDVAMSGQPLPPVLPPEYIPP 306
Score = 106 bits (255), Expect = 5e-22
Identities = 83/291 (28%), Positives = 126/291 (43%), Gaps = 34/291 (11%)
Query: 928 RGQSGWFPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDP 987
+GQ GWFP+SYV+ ++ P + T ++ +S+ +L V P
Sbjct: 950 QGQKGWFPKSYVKLISGP----------IRKSTSMDS--------GSSESPASLKRVASP 991
Query: 988 GRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIF 1047
++PV GE +IA Y Y SSE GDL F+ G+ I V ++DGDWWTG +G + G+F
Sbjct: 992 A---AKPVV---SGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTVGDKAGVF 1045
Query: 1048 PSNYVSREAAPAATSXXXXXXXXXXXXXXXXXXXXXXTSPPNTTPPIPASQLIWTSNELA 1107
PSNYV + + + + T P T LI N
Sbjct: 1046 PSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIQKKNPGG 1105
Query: 1108 YTSVTFLLAQDQKSSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRRKHEIVQALAS 1167
+ L A+ +K I A + + + I +
Sbjct: 1106 WWEGE-LQARGKKRQ--IGWFPANYVKLLSPGTSKITPTEPPKSTALAAVCQVI--GMYD 1160
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKV 1218
YTA + ++L+ KGQ++ V K D WW+GE+ N QVG FP++YVK+
Sbjct: 1161 YTAQNDDELAFNKGQIINVLNKEDPDWWKGEV-----NGQVGLFPSNYVKL 1206
Score = 106 bits (254), Expect = 6e-22
Identities = 47/88 (53%), Positives = 61/88 (69%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGK 63
D W I E AK + F +L P++G +TG+QA+ F QS LP PVL QIW+LAD N DG+
Sbjct: 13 DIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGR 72
Query: 64 LDLKEFSIACKIINLKLRGLEVPKMLPP 91
+D EFSIA K+I LKL+G ++P LPP
Sbjct: 73 MDQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 94.7 bits (225), Expect = 2e-18
Identities = 92/348 (26%), Positives = 146/348 (41%), Gaps = 41/348 (11%)
Query: 980 ALPAVVDPGRTVSE---PVSVEDDGE--FYIASYPYSSSEPGDLVFEAGERIEVVR-RDG 1033
A PAV P T + +S +++ + +Y A YP+ S ++ + G+ + V + G
Sbjct: 716 AKPAVQAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMVDESQTG 775
Query: 1034 D--WWTGRIGARTGIFPSNYVSR---EAAPAATSXXXXXXXXXXXXXXXXXX---XXXXT 1085
+ W G + +TG FP+NY + PA +
Sbjct: 776 EPGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTDSTSAPAPKLALRETPAPLAVTS 835
Query: 1086 SPPNTTPPIPAS-QLIW--TSNELAYTSVTFLLAQDQKSSTPISSEVAMITDXXXXXXXX 1142
S P+TTP A W ++NE T A + P + ++
Sbjct: 836 SEPSTTPNNWADFSSTWPTSTNEKPETDNWDAWAAQPSLTVPSAGQLRQ-----RSAFTP 890
Query: 1143 XXXXDSGRDSVTGR-RKHEIVQALASYT--ATSPEQLSLMKGQLLVVRKKADSGWWEGEL 1199
S V G+ K E +QA A Y A L+ K ++ V ++ D WW GE+
Sbjct: 891 ATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDM-WWFGEV 949
Query: 1200 QAKGRNRQVGWFPASYVKVL-----QSSGRTSGRTTPVLSSKMDALPTETVI---DKVVA 1251
Q Q GWFP SYVK++ +S+ SG + S K A P + ++ +A
Sbjct: 950 QG-----QKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKPVVSGEEFIA 1004
Query: 1252 LYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+Y Y + +L+F++ D+I VT + D WW G + G+FPSNYV
Sbjct: 1005 MYTYESSEQGDLTFQQGDVILVTKKDGD--WWTGTVGDKAGVFPSNYV 1050
Score = 71.3 bits (167), Expect = 2e-11
Identities = 36/87 (41%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 355 WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKL 414
W + ++ K+ Q F++ + +G +G QAR+ QS LPQ LAQIWALAD++ DG++
Sbjct: 15 WAITVEERAKHDQQFHSL-KPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRM 73
Query: 415 GCEEFVLAMYLCEKATQGEPVPARLPP 441
EF +AM L + QG +P+ LPP
Sbjct: 74 DQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 69.7 bits (163), Expect = 6e-11
Identities = 32/90 (35%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F + ++G+LTG QA+ ++QS LP L IW+L+D + DGKL
Sbjct: 215 WAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKL 274
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A +I++ + G +P +LPP I
Sbjct: 275 TAEEFILAMHLIDVAMSGQPLPPVLPPEYI 304
Score = 62.5 bits (145), Expect = 1e-08
Identities = 48/145 (33%), Positives = 72/145 (49%), Gaps = 23/145 (15%)
Query: 1165 LASYTATSPEQ--LSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSS 1222
+A YT S EQ L+ +G +++V KK D WW G + K G FP++YV++ S
Sbjct: 1003 IAMYTYESSEQGDLTFQQGDVILVTKK-DGDWWTGTVGDKA-----GVFPSNYVRLKDSE 1056
Query: 1223 GRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAW 1282
G + T L K + I +V+A YTA ++L+ +I + + W
Sbjct: 1057 GSGTAGKTGSLGKKPE-------IAQVIA--SYTATGPEQLTLAPGQLILI-QKKNPGGW 1106
Query: 1283 WQGEL--RG---MVGLFPSNYVTKL 1302
W+GEL RG +G FP+NYV L
Sbjct: 1107 WEGELQARGKKRQIGWFPANYVKLL 1131
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/90 (31%), Positives = 52/90 (57%)
Query: 633 QCQLEWEKKRTRELEALRSEEQSKVLSLKAKCQSLSAQLGAESVRCSTLAASIRDTRTAV 692
Q QLEWE+ R +EL R++EQ ++ LKAK ++L +L A + + L ++D R +
Sbjct: 444 QRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRL 503
Query: 693 AADKRTIDGMRSDRDSSMAEMQQLKARVKE 722
++ I+ R+ +AE+ L+ +++E
Sbjct: 504 TTQRQEIESTNKSRELRIAEITHLQQQLQE 533
Score = 52.8 bits (121), Expect = 8e-06
Identities = 24/54 (44%), Positives = 36/54 (66%), Gaps = 3/54 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQ--DPAWWQGELRGMVGLFPSNYVTKL 1302
ALYP+ +++ DE++ + DI+ V D SQ +P W GEL+G G FP+NY K+
Sbjct: 747 ALYPFESRSHDEITIQPGDIVMV-DESQTGEPGWLGGELKGKTGWFPANYAEKI 799
Score = 52.0 bits (119), Expect = 1e-05
Identities = 24/54 (44%), Positives = 36/54 (66%), Gaps = 3/54 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
ALYP+ A+ + L+F K+D+I V + Q WW GE++G G FP +YV KL++
Sbjct: 915 ALYPWRAKKDNHLNFNKNDVITVLE--QQDMWWFGEVQGQKGWFPKSYV-KLIS 965
Score = 49.2 bits (112), Expect = 1e-04
Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 6/81 (7%)
Query: 887 WRCVYPFVGRSADELSVQPGDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESYVE-----D 941
+R +YPF RS DE+++QPGD IV +G++GWFP +Y E +
Sbjct: 745 YRALYPFESRSHDEITIQPGD-IVMVDESQTGEPGWLGGELKGKTGWFPANYAEKIPENE 803
Query: 942 LNAPTAFVTEVIETLEPKTQL 962
+ AP VT+ PK L
Sbjct: 804 VPAPVKPVTDSTSAPAPKLAL 824
Score = 33.9 bits (74), Expect = 3.8
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 466 RRENMARGQAELERRRTQLADAQMKEKVRGRGLNQSQ 502
+REN RG ELE+RR L + Q KE+ R L +++
Sbjct: 354 KRENFERGNLELEKRRQALLEQQRKEQERLAQLERAE 390
>U61166-1|AAC50592.1| 520|Homo sapiens SH3 domain-containing protein
SH3P17 protein.
Length = 520
Score = 164 bits (398), Expect = 2e-39
Identities = 79/140 (56%), Positives = 101/140 (72%), Gaps = 7/140 (5%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVL 1219
EI Q +ASYTAT PEQL+L GQL+++RKK GWWEGELQA+G+ RQ+GWFPA+YVK+L
Sbjct: 377 EIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLL 436
Query: 1220 QSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQD 1279
S G + + TP K AL + +V+ +Y YTAQN DEL+F K II V ++ +D
Sbjct: 437 -SPG--TSKITPTEPPKSTAL---AAVCQVIGMYDYTAQNDDELAFNKGQIINVLNK-ED 489
Query: 1280 PAWWQGELRGMVGLFPSNYV 1299
P WW+GE+ G VGLFPSNYV
Sbjct: 490 PDWWKGEVNGQVGLFPSNYV 509
Score = 78.6 bits (185), Expect = 1e-13
Identities = 95/358 (26%), Positives = 148/358 (41%), Gaps = 48/358 (13%)
Query: 980 ALPAVVDPGRTVSE---PVSVEDDGE--FYIASYPYSSSEPGDLVFEAGERIEVVR-RDG 1033
A PAV P T + +S +++ + +Y A YP+ S ++ + G+ + V + G
Sbjct: 92 AKPAVQAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMVDESQTG 151
Query: 1034 D--WWTGRIGARTGIFPSNYVSR---EAAPAATSXXXXXXXXXXXXXXXXXX---XXXXT 1085
+ W G + +TG FP+NY + PA +
Sbjct: 152 EPGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTDSTSAPAPKLALRETPAPLAVTS 211
Query: 1086 SPPNTTPPIPAS-QLIW--TSNELAYTSVTFLLAQDQKSSTPISSEVAMITDXXXXXXXX 1142
S P+TTP A W ++NE T A + P + ++
Sbjct: 212 SEPSTTPNNWADFSSTWPTSTNEKPETDNWDAWAAQPSLTVPSAGQLRQ-----RSAFTP 266
Query: 1143 XXXXDSGRDSVTGR-RKHEIVQALASYT--ATSPEQLSLMKGQLLVVRKKADSGWWEGEL 1199
S V G+ K E +QA A Y A L+ K ++ V ++ D WW GE+
Sbjct: 267 ATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDM-WWFGEV 325
Query: 1200 QAKGRNRQVGWFPASYVKVL-----QSSGRTSGRTTPVLSSKMDALPT--ETVIDKVVA- 1251
Q Q GWFP SYVK++ +S+ SG + S K A P V + +A
Sbjct: 326 QG-----QKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKPVVSGEEIAQ 380
Query: 1252 -LYPYTAQNADELSFEKDDIIAVTDRSQDP-AWWQGEL--RG---MVGLFPSNYVTKL 1302
+ YTA ++L+ +I + R ++P WW+GEL RG +G FP+NYV L
Sbjct: 381 VIASYTATGPEQLTLAPGQLILI--RKKNPGGWWEGELQARGKKRQIGWFPANYVKLL 436
Score = 52.0 bits (119), Expect = 1e-05
Identities = 24/54 (44%), Positives = 36/54 (66%), Gaps = 3/54 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
ALYP+ A+ + L+F K+D+I V + Q WW GE++G G FP +YV KL++
Sbjct: 291 ALYPWRAKKDNHLNFNKNDVITVLE--QQDMWWFGEVQGQKGWFPKSYV-KLIS 341
Score = 50.4 bits (115), Expect = 4e-05
Identities = 24/57 (42%), Positives = 36/57 (63%), Gaps = 5/57 (8%)
Query: 1162 VQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKV 1218
V + YTA + ++L+ KGQ++ V K D WW+GE+ N QVG FP++YVK+
Sbjct: 460 VIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEV-----NGQVGLFPSNYVKL 511
Score = 50.4 bits (115), Expect = 4e-05
Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
I Y Y++ +L F G+ I V+ + D DWW G + + G+FPSNYV
Sbjct: 461 IGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYV 509
Score = 49.2 bits (112), Expect = 1e-04
Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 6/81 (7%)
Query: 887 WRCVYPFVGRSADELSVQPGDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESYVE-----D 941
+R +YPF RS DE+++QPGD IV +G++GWFP +Y E +
Sbjct: 121 YRALYPFESRSHDEITIQPGD-IVMVDESQTGEPGWLGGELKGKTGWFPANYAEKIPENE 179
Query: 942 LNAPTAFVTEVIETLEPKTQL 962
+ AP VT+ PK L
Sbjct: 180 VPAPVKPVTDSTSAPAPKLAL 200
Score = 42.3 bits (95), Expect = 0.011
Identities = 37/131 (28%), Positives = 62/131 (47%), Gaps = 29/131 (22%)
Query: 928 RGQSGWFPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDP 987
+GQ GWFP+SYV+ ++ P + T ++ +S+ +L V P
Sbjct: 326 QGQKGWFPKSYVKLISGP----------IRKSTSMDS--------GSSESPASLKRVASP 367
Query: 988 GRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRD-GDWWTGRIGAR--- 1043
++PV ++ IASY +++ P L G+ I + +++ G WW G + AR
Sbjct: 368 A---AKPVVSGEEIAQVIASY--TATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKK 422
Query: 1044 --TGIFPSNYV 1052
G FP+NYV
Sbjct: 423 RQIGWFPANYV 433
>BC117560-1|AAI17561.1| 1144|Homo sapiens ITSN1 protein protein.
Length = 1144
Score = 164 bits (398), Expect = 2e-39
Identities = 79/140 (56%), Positives = 101/140 (72%), Gaps = 7/140 (5%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVL 1219
EI Q +ASYTAT PEQL+L GQL+++RKK GWWEGELQA+G+ RQ+GWFPA+YVK+L
Sbjct: 1001 EIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLL 1060
Query: 1220 QSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQD 1279
S G + + TP K AL + +V+ +Y YTAQN DEL+F K II V ++ +D
Sbjct: 1061 -SPG--TSKITPTEPPKSTAL---AAVCQVIGMYDYTAQNDDELAFNKGQIINVLNK-ED 1113
Query: 1280 PAWWQGELRGMVGLFPSNYV 1299
P WW+GE+ G VGLFPSNYV
Sbjct: 1114 PDWWKGEVNGQVGLFPSNYV 1133
Score = 134 bits (323), Expect = 3e-30
Identities = 82/211 (38%), Positives = 110/211 (52%), Gaps = 10/211 (4%)
Query: 242 PIMSSQPLI--SASTISAQPLGTMQPLIGTAPPIMGATQALIQSPPLSGPQQPAPVTAAS 299
P+M QP+ SA + +M PL AP MG+ + SP L A V +
Sbjct: 100 PVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLA 159
Query: 300 FGGXXXXXXXXXXXXGQPVTSTPIAALNKEVISKPGSVVTSP---EVPMGVMSPPPM-EW 355
G P + P ++ S PGS + + V S PP+ EW
Sbjct: 160 NGAPPVIQPLPAFA--HPAATLPKSSSFSR--SGPGSQLNTKLQKAQSFDVASVPPVAEW 215
Query: 356 GVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLG 415
VPQ +LKY QLFN+ D+ +G +G QAR+I++QS LPQ LA IW L+D+D DGKL
Sbjct: 216 AVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLT 275
Query: 416 CEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
EEF+LAM+L + A G+P+P LPPE IPP
Sbjct: 276 AEEFILAMHLIDVAMSGQPLPPVLPPEYIPP 306
Score = 106 bits (254), Expect = 6e-22
Identities = 47/88 (53%), Positives = 61/88 (69%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGK 63
D W I E AK + F +L P++G +TG+QA+ F QS LP PVL QIW+LAD N DG+
Sbjct: 13 DIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGR 72
Query: 64 LDLKEFSIACKIINLKLRGLEVPKMLPP 91
+D EFSIA K+I LKL+G ++P LPP
Sbjct: 73 MDQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 78.6 bits (185), Expect = 1e-13
Identities = 95/358 (26%), Positives = 148/358 (41%), Gaps = 48/358 (13%)
Query: 980 ALPAVVDPGRTVSE---PVSVEDDGE--FYIASYPYSSSEPGDLVFEAGERIEVVR-RDG 1033
A PAV P T + +S +++ + +Y A YP+ S ++ + G+ + V + G
Sbjct: 716 AKPAVQAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMVDESQTG 775
Query: 1034 D--WWTGRIGARTGIFPSNYVSR---EAAPAATSXXXXXXXXXXXXXXXXXX---XXXXT 1085
+ W G + +TG FP+NY + PA +
Sbjct: 776 EPGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTDSTSAPAPKLALRETPAPLAVTS 835
Query: 1086 SPPNTTPPIPAS-QLIW--TSNELAYTSVTFLLAQDQKSSTPISSEVAMITDXXXXXXXX 1142
S P+TTP A W ++NE T A + P + ++
Sbjct: 836 SEPSTTPNNWADFSSTWPTSTNEKPETDNWDAWAAQPSLTVPSAGQLRQ-----RSAFTP 890
Query: 1143 XXXXDSGRDSVTGR-RKHEIVQALASYT--ATSPEQLSLMKGQLLVVRKKADSGWWEGEL 1199
S V G+ K E +QA A Y A L+ K ++ V ++ D WW GE+
Sbjct: 891 ATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDM-WWFGEV 949
Query: 1200 QAKGRNRQVGWFPASYVKVL-----QSSGRTSGRTTPVLSSKMDALPT--ETVIDKVVA- 1251
Q Q GWFP SYVK++ +S+ SG + S K A P V + +A
Sbjct: 950 QG-----QKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKPVVSGEEIAQ 1004
Query: 1252 -LYPYTAQNADELSFEKDDIIAVTDRSQDP-AWWQGEL--RG---MVGLFPSNYVTKL 1302
+ YTA ++L+ +I + R ++P WW+GEL RG +G FP+NYV L
Sbjct: 1005 VIASYTATGPEQLTLAPGQLILI--RKKNPGGWWEGELQARGKKRQIGWFPANYVKLL 1060
Score = 71.3 bits (167), Expect = 2e-11
Identities = 36/87 (41%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 355 WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKL 414
W + ++ K+ Q F++ + +G +G QAR+ QS LPQ LAQIWALAD++ DG++
Sbjct: 15 WAITVEERAKHDQQFHSL-KPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRM 73
Query: 415 GCEEFVLAMYLCEKATQGEPVPARLPP 441
EF +AM L + QG +P+ LPP
Sbjct: 74 DQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 69.7 bits (163), Expect = 6e-11
Identities = 32/90 (35%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F + ++G+LTG QA+ ++QS LP L IW+L+D + DGKL
Sbjct: 215 WAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKL 274
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A +I++ + G +P +LPP I
Sbjct: 275 TAEEFILAMHLIDVAMSGQPLPPVLPPEYI 304
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/90 (31%), Positives = 52/90 (57%)
Query: 633 QCQLEWEKKRTRELEALRSEEQSKVLSLKAKCQSLSAQLGAESVRCSTLAASIRDTRTAV 692
Q QLEWE+ R +EL R++EQ ++ LKAK ++L +L A + + L ++D R +
Sbjct: 444 QRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRL 503
Query: 693 AADKRTIDGMRSDRDSSMAEMQQLKARVKE 722
++ I+ R+ +AE+ L+ +++E
Sbjct: 504 TTQRQEIESTNKSRELRIAEITHLQQQLQE 533
Score = 52.0 bits (119), Expect = 1e-05
Identities = 24/54 (44%), Positives = 36/54 (66%), Gaps = 3/54 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
ALYP+ A+ + L+F K+D+I V + Q WW GE++G G FP +YV KL++
Sbjct: 915 ALYPWRAKKDNHLNFNKNDVITVLE--QQDMWWFGEVQGQKGWFPKSYV-KLIS 965
Score = 50.4 bits (115), Expect = 4e-05
Identities = 24/57 (42%), Positives = 36/57 (63%), Gaps = 5/57 (8%)
Query: 1162 VQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKV 1218
V + YTA + ++L+ KGQ++ V K D WW+GE+ N QVG FP++YVK+
Sbjct: 1084 VIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEV-----NGQVGLFPSNYVKL 1135
Score = 50.4 bits (115), Expect = 4e-05
Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
I Y Y++ +L F G+ I V+ + D DWW G + + G+FPSNYV
Sbjct: 1085 IGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYV 1133
Score = 49.2 bits (112), Expect = 1e-04
Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 6/81 (7%)
Query: 887 WRCVYPFVGRSADELSVQPGDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESYVE-----D 941
+R +YPF RS DE+++QPGD IV +G++GWFP +Y E +
Sbjct: 745 YRALYPFESRSHDEITIQPGD-IVMVDESQTGEPGWLGGELKGKTGWFPANYAEKIPENE 803
Query: 942 LNAPTAFVTEVIETLEPKTQL 962
+ AP VT+ PK L
Sbjct: 804 VPAPVKPVTDSTSAPAPKLAL 824
Score = 42.3 bits (95), Expect = 0.011
Identities = 37/131 (28%), Positives = 62/131 (47%), Gaps = 29/131 (22%)
Query: 928 RGQSGWFPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDP 987
+GQ GWFP+SYV+ ++ P + T ++ +S+ +L V P
Sbjct: 950 QGQKGWFPKSYVKLISGP----------IRKSTSMDS--------GSSESPASLKRVASP 991
Query: 988 GRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRD-GDWWTGRIGAR--- 1043
++PV ++ IASY +++ P L G+ I + +++ G WW G + AR
Sbjct: 992 A---AKPVVSGEEIAQVIASY--TATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKK 1046
Query: 1044 --TGIFPSNYV 1052
G FP+NYV
Sbjct: 1047 RQIGWFPANYV 1057
Score = 33.9 bits (74), Expect = 3.8
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 466 RRENMARGQAELERRRTQLADAQMKEKVRGRGLNQSQ 502
+REN RG ELE+RR L + Q KE+ R L +++
Sbjct: 354 KRENFERGNLELEKRRQALLEQQRKEQERLAQLERAE 390
>DQ679755-1|ABG74696.1| 1149|Homo sapiens intersectin 1 short form
variant 7 protein.
Length = 1149
Score = 163 bits (397), Expect = 3e-39
Identities = 77/140 (55%), Positives = 99/140 (70%), Gaps = 7/140 (5%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVL 1219
EI Q +ASYTAT PEQL+L GQL+++RKK GWWEGELQA+G+ RQ+GWFPA+YVK+L
Sbjct: 1006 EIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLL 1065
Query: 1220 QSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQD 1279
+ + TP K AL + +V+ +Y YTAQN DEL+F K II V ++ +D
Sbjct: 1066 NPG---TSKITPTEPPKSTAL---AAVCQVIGMYDYTAQNDDELAFNKGQIINVLNK-ED 1118
Query: 1280 PAWWQGELRGMVGLFPSNYV 1299
P WW+GE+ G VGLFPSNYV
Sbjct: 1119 PDWWKGEVNGQVGLFPSNYV 1138
Score = 134 bits (323), Expect = 3e-30
Identities = 82/211 (38%), Positives = 110/211 (52%), Gaps = 10/211 (4%)
Query: 242 PIMSSQPLI--SASTISAQPLGTMQPLIGTAPPIMGATQALIQSPPLSGPQQPAPVTAAS 299
P+M QP+ SA + +M PL AP MG+ + SP L A V +
Sbjct: 100 PVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLA 159
Query: 300 FGGXXXXXXXXXXXXGQPVTSTPIAALNKEVISKPGSVVTSP---EVPMGVMSPPPM-EW 355
G P + P ++ S PGS + + V S PP+ EW
Sbjct: 160 NGAPPVIQPLPAFA--HPAATLPKSSSFSR--SGPGSQLNTKLQKAQSFDVASVPPVAEW 215
Query: 356 GVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLG 415
VPQ +LKY QLFN+ D+ +G +G QAR+I++QS LPQ LA IW L+D+D DGKL
Sbjct: 216 AVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLT 275
Query: 416 CEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
EEF+LAM+L + A G+P+P LPPE IPP
Sbjct: 276 AEEFILAMHLIDVAMSGQPLPPVLPPEYIPP 306
Score = 106 bits (254), Expect = 6e-22
Identities = 47/88 (53%), Positives = 61/88 (69%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGK 63
D W I E AK + F +L P++G +TG+QA+ F QS LP PVL QIW+LAD N DG+
Sbjct: 13 DIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGR 72
Query: 64 LDLKEFSIACKIINLKLRGLEVPKMLPP 91
+D EFSIA K+I LKL+G ++P LPP
Sbjct: 73 MDQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 82.2 bits (194), Expect = 1e-14
Identities = 100/365 (27%), Positives = 153/365 (41%), Gaps = 54/365 (14%)
Query: 980 ALPAVVDPGRTVSE---PVSVEDDGE--FYIASYPYSSS-------EPGDLVFEAGERIE 1027
A PAV P T + +S +++ + +Y A YP+ S +PGD+V GE ++
Sbjct: 716 AKPAVQAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMVKGEWVD 775
Query: 1028 VVRR-DGDWWTGRIGARTGIFPSNYVSR---EAAPAATSXXXXXXXXXXXXXXXXXX--- 1080
+ + W G + +TG FP+NY + PA
Sbjct: 776 ESQTGEPGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTDSTSAPAPKLALRETPAP 835
Query: 1081 XXXXTSPPNTTPPIPAS-QLIW--TSNELAYTSVTFLLAQDQKSSTPISSEVAMITDXXX 1137
+S P+TTP A W ++NE T A + P + ++
Sbjct: 836 LAVTSSEPSTTPNNWADFSSTWPTSTNEKPETDNWDAWAAQPSLTVPSAGQLRQ-----R 890
Query: 1138 XXXXXXXXXDSGRDSVTGR-RKHEIVQALASYT--ATSPEQLSLMKGQLLVVRKKADSGW 1194
S V G+ K E +QA A Y A L+ K ++ V ++ D W
Sbjct: 891 SAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDM-W 949
Query: 1195 WEGELQAKGRNRQVGWFPASYVKVL-----QSSGRTSGRTTPVLSSKMDALPT--ETVID 1247
W GE+Q Q GWFP SYVK++ +S+ SG + S K A P V
Sbjct: 950 WFGEVQG-----QKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKPVVSG 1004
Query: 1248 KVVA--LYPYTAQNADELSFEKDDIIAVTDRSQDP-AWWQGEL--RG---MVGLFPSNYV 1299
+ +A + YTA ++L+ +I + R ++P WW+GEL RG +G FP+NYV
Sbjct: 1005 EEIAQVIASYTATGPEQLTLAPGQLILI--RKKNPGGWWEGELQARGKKRQIGWFPANYV 1062
Query: 1300 TKLVN 1304
KL+N
Sbjct: 1063 -KLLN 1066
Score = 71.3 bits (167), Expect = 2e-11
Identities = 36/87 (41%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 355 WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKL 414
W + ++ K+ Q F++ + +G +G QAR+ QS LPQ LAQIWALAD++ DG++
Sbjct: 15 WAITVEERAKHDQQFHSL-KPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRM 73
Query: 415 GCEEFVLAMYLCEKATQGEPVPARLPP 441
EF +AM L + QG +P+ LPP
Sbjct: 74 DQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 69.7 bits (163), Expect = 6e-11
Identities = 32/90 (35%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F + ++G+LTG QA+ ++QS LP L IW+L+D + DGKL
Sbjct: 215 WAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKL 274
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A +I++ + G +P +LPP I
Sbjct: 275 TAEEFILAMHLIDVAMSGQPLPPVLPPEYI 304
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/90 (31%), Positives = 52/90 (57%)
Query: 633 QCQLEWEKKRTRELEALRSEEQSKVLSLKAKCQSLSAQLGAESVRCSTLAASIRDTRTAV 692
Q QLEWE+ R +EL R++EQ ++ LKAK ++L +L A + + L ++D R +
Sbjct: 444 QRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRL 503
Query: 693 AADKRTIDGMRSDRDSSMAEMQQLKARVKE 722
++ I+ R+ +AE+ L+ +++E
Sbjct: 504 TTQRQEIESTNKSRELRIAEITHLQQQLQE 533
Score = 50.4 bits (115), Expect = 4e-05
Identities = 24/57 (42%), Positives = 36/57 (63%), Gaps = 5/57 (8%)
Query: 1162 VQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKV 1218
V + YTA + ++L+ KGQ++ V K D WW+GE+ N QVG FP++YVK+
Sbjct: 1089 VIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEV-----NGQVGLFPSNYVKL 1140
Score = 50.4 bits (115), Expect = 4e-05
Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
I Y Y++ +L F G+ I V+ + D DWW G + + G+FPSNYV
Sbjct: 1090 IGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYV 1138
Score = 46.4 bits (105), Expect = 7e-04
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 9/85 (10%)
Query: 887 WRCVYPFVGRSADELSVQPGDLIVXXXXXXXXXXXX----XXXXXRGQSGWFPESYVE-- 940
+R +YPF RS DE+++QPGD+++ +G++GWFP +Y E
Sbjct: 745 YRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804
Query: 941 ---DLNAPTAFVTEVIETLEPKTQL 962
++ AP VT+ PK L
Sbjct: 805 PENEVPAPVKPVTDSTSAPAPKLAL 829
Score = 42.3 bits (95), Expect = 0.011
Identities = 37/131 (28%), Positives = 62/131 (47%), Gaps = 29/131 (22%)
Query: 928 RGQSGWFPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDP 987
+GQ GWFP+SYV+ ++ P + T ++ +S+ +L V P
Sbjct: 955 QGQKGWFPKSYVKLISGP----------IRKSTSMDS--------GSSESPASLKRVASP 996
Query: 988 GRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRD-GDWWTGRIGAR--- 1043
++PV ++ IASY +++ P L G+ I + +++ G WW G + AR
Sbjct: 997 A---AKPVVSGEEIAQVIASY--TATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKK 1051
Query: 1044 --TGIFPSNYV 1052
G FP+NYV
Sbjct: 1052 RQIGWFPANYV 1062
Score = 33.9 bits (74), Expect = 3.8
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 466 RRENMARGQAELERRRTQLADAQMKEKVRGRGLNQSQ 502
+REN RG ELE+RR L + Q KE+ R L +++
Sbjct: 354 KRENFERGNLELEKRRQALLEQQRKEQERLAQLERAE 390
>DQ679754-1|ABG74695.1| 1144|Homo sapiens intersectin 1 short form
variant 6 protein.
Length = 1144
Score = 163 bits (397), Expect = 3e-39
Identities = 77/140 (55%), Positives = 99/140 (70%), Gaps = 7/140 (5%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVL 1219
EI Q +ASYTAT PEQL+L GQL+++RKK GWWEGELQA+G+ RQ+GWFPA+YVK+L
Sbjct: 1001 EIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLL 1060
Query: 1220 QSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQD 1279
+ + TP K AL + +V+ +Y YTAQN DEL+F K II V ++ +D
Sbjct: 1061 NPG---TSKITPTEPPKSTAL---AAVCQVIGMYDYTAQNDDELAFNKGQIINVLNK-ED 1113
Query: 1280 PAWWQGELRGMVGLFPSNYV 1299
P WW+GE+ G VGLFPSNYV
Sbjct: 1114 PDWWKGEVNGQVGLFPSNYV 1133
Score = 133 bits (322), Expect = 3e-30
Identities = 82/211 (38%), Positives = 110/211 (52%), Gaps = 10/211 (4%)
Query: 242 PIMSSQPLI--SASTISAQPLGTMQPLIGTAPPIMGATQALIQSPPLSGPQQPAPVTAAS 299
P+M QP+ SA + +M PL AP MG+ + SP L A V +
Sbjct: 100 PVMKQQPVAISSAPPFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLA 159
Query: 300 FGGXXXXXXXXXXXXGQPVTSTPIAALNKEVISKPGSVVTSP---EVPMGVMSPPPM-EW 355
G P + P ++ S PGS + + V S PP+ EW
Sbjct: 160 NGAPPVIQPLPAFA--HPAATLPKSSSFSR--SGPGSQLNTKLQKAQSFDVASVPPVAEW 215
Query: 356 GVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLG 415
VPQ +LKY QLFN+ D+ +G +G QAR+I++QS LPQ LA IW L+D+D DGKL
Sbjct: 216 AVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLT 275
Query: 416 CEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
EEF+LAM+L + A G+P+P LPPE IPP
Sbjct: 276 AEEFILAMHLIDVAMSGQPLPPVLPPEYIPP 306
Score = 106 bits (254), Expect = 6e-22
Identities = 47/88 (53%), Positives = 61/88 (69%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGK 63
D W I E AK + F +L P++G +TG+QA+ F QS LP PVL QIW+LAD N DG+
Sbjct: 13 DIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGR 72
Query: 64 LDLKEFSIACKIINLKLRGLEVPKMLPP 91
+D EFSIA K+I LKL+G ++P LPP
Sbjct: 73 MDQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 80.2 bits (189), Expect = 4e-14
Identities = 97/360 (26%), Positives = 151/360 (41%), Gaps = 49/360 (13%)
Query: 980 ALPAVVDPGRTVSE---PVSVEDDGE--FYIASYPYSSSEPGDLVFEAGERIEVVR-RDG 1033
A PAV P T + +S +++ + +Y A YP+ S ++ + G+ + V + G
Sbjct: 716 AKPAVQAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMVDESQTG 775
Query: 1034 D--WWTGRIGARTGIFPSNYVSR---EAAPAATSXXXXXXXXXXXXXXXXXX---XXXXT 1085
+ W G + +TG FP+NY + PA +
Sbjct: 776 EPGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTDSTSAPAPKLALRETPAPLAVTS 835
Query: 1086 SPPNTTPPIPAS-QLIW--TSNELAYTSVTFLLAQDQKSSTPISSEVAMITDXXXXXXXX 1142
S P+TTP A W ++NE T A + P + ++
Sbjct: 836 SEPSTTPNNWADFSSTWPTSTNEKPETDNWDAWAAQPSLTVPSAGQLRQ-----RSAFTP 890
Query: 1143 XXXXDSGRDSVTGR-RKHEIVQALASYT--ATSPEQLSLMKGQLLVVRKKADSGWWEGEL 1199
S V G+ K E +QA A Y A L+ K ++ V ++ D WW GE+
Sbjct: 891 ATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDM-WWFGEV 949
Query: 1200 QAKGRNRQVGWFPASYVKVL-----QSSGRTSGRTTPVLSSKMDALPT--ETVIDKVVA- 1251
Q Q GWFP SYVK++ +S+ SG + S K A P V + +A
Sbjct: 950 QG-----QKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKPVVSGEEIAQ 1004
Query: 1252 -LYPYTAQNADELSFEKDDIIAVTDRSQDP-AWWQGEL--RG---MVGLFPSNYVTKLVN 1304
+ YTA ++L+ +I + R ++P WW+GEL RG +G FP+NYV KL+N
Sbjct: 1005 VIASYTATGPEQLTLAPGQLILI--RKKNPGGWWEGELQARGKKRQIGWFPANYV-KLLN 1061
Score = 71.3 bits (167), Expect = 2e-11
Identities = 36/87 (41%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 355 WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKL 414
W + ++ K+ Q F++ + +G +G QAR+ QS LPQ LAQIWALAD++ DG++
Sbjct: 15 WAITVEERAKHDQQFHSL-KPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRM 73
Query: 415 GCEEFVLAMYLCEKATQGEPVPARLPP 441
EF +AM L + QG +P+ LPP
Sbjct: 74 DQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 69.7 bits (163), Expect = 6e-11
Identities = 32/90 (35%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F + ++G+LTG QA+ ++QS LP L IW+L+D + DGKL
Sbjct: 215 WAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKL 274
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A +I++ + G +P +LPP I
Sbjct: 275 TAEEFILAMHLIDVAMSGQPLPPVLPPEYI 304
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/90 (31%), Positives = 52/90 (57%)
Query: 633 QCQLEWEKKRTRELEALRSEEQSKVLSLKAKCQSLSAQLGAESVRCSTLAASIRDTRTAV 692
Q QLEWE+ R +EL R++EQ ++ LKAK ++L +L A + + L ++D R +
Sbjct: 444 QRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRL 503
Query: 693 AADKRTIDGMRSDRDSSMAEMQQLKARVKE 722
++ I+ R+ +AE+ L+ +++E
Sbjct: 504 TTQRQEIESTNKSRELRIAEITHLQQQLQE 533
Score = 50.4 bits (115), Expect = 4e-05
Identities = 24/57 (42%), Positives = 36/57 (63%), Gaps = 5/57 (8%)
Query: 1162 VQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKV 1218
V + YTA + ++L+ KGQ++ V K D WW+GE+ N QVG FP++YVK+
Sbjct: 1084 VIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEV-----NGQVGLFPSNYVKL 1135
Score = 50.4 bits (115), Expect = 4e-05
Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
I Y Y++ +L F G+ I V+ + D DWW G + + G+FPSNYV
Sbjct: 1085 IGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYV 1133
Score = 49.2 bits (112), Expect = 1e-04
Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 6/81 (7%)
Query: 887 WRCVYPFVGRSADELSVQPGDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESYVE-----D 941
+R +YPF RS DE+++QPGD IV +G++GWFP +Y E +
Sbjct: 745 YRALYPFESRSHDEITIQPGD-IVMVDESQTGEPGWLGGELKGKTGWFPANYAEKIPENE 803
Query: 942 LNAPTAFVTEVIETLEPKTQL 962
+ AP VT+ PK L
Sbjct: 804 VPAPVKPVTDSTSAPAPKLAL 824
Score = 42.3 bits (95), Expect = 0.011
Identities = 37/131 (28%), Positives = 62/131 (47%), Gaps = 29/131 (22%)
Query: 928 RGQSGWFPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDP 987
+GQ GWFP+SYV+ ++ P + T ++ +S+ +L V P
Sbjct: 950 QGQKGWFPKSYVKLISGP----------IRKSTSMDS--------GSSESPASLKRVASP 991
Query: 988 GRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRD-GDWWTGRIGAR--- 1043
++PV ++ IASY +++ P L G+ I + +++ G WW G + AR
Sbjct: 992 A---AKPVVSGEEIAQVIASY--TATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKK 1046
Query: 1044 --TGIFPSNYV 1052
G FP+NYV
Sbjct: 1047 RQIGWFPANYV 1057
Score = 33.9 bits (74), Expect = 3.8
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 466 RRENMARGQAELERRRTQLADAQMKEKVRGRGLNQSQ 502
+REN RG ELE+RR L + Q KE+ R L +++
Sbjct: 354 KRENFERGNLELEKRRQALLEQQRKEQERLAQLERAE 390
>AF180522-1|AAD53183.1| 187|Homo sapiens intersectin short form 2
protein.
Length = 187
Score = 161 bits (392), Expect = 1e-38
Identities = 78/140 (55%), Positives = 100/140 (71%), Gaps = 7/140 (5%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVL 1219
EI Q +ASYTA PEQL+L GQL+++RKK GWWEGELQA+G+ RQ+GWFPA+YVK+L
Sbjct: 44 EIAQVIASYTAAGPEQLTLAPGQLILIRKKNPRGWWEGELQARGKKRQIGWFPANYVKLL 103
Query: 1220 QSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQD 1279
S G + + TP K AL + +V+ +Y YTAQN DEL+F K II V ++ +D
Sbjct: 104 -SPG--TSKITPTEPPKSTAL---AAVCQVIGMYDYTAQNDDELAFNKGQIINVLNK-ED 156
Query: 1280 PAWWQGELRGMVGLFPSNYV 1299
P WW+GE+ G VGLFPSNYV
Sbjct: 157 PDWWKGEVNGQVGLFPSNYV 176
Score = 50.4 bits (115), Expect = 4e-05
Identities = 24/57 (42%), Positives = 36/57 (63%), Gaps = 5/57 (8%)
Query: 1162 VQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKV 1218
V + YTA + ++L+ KGQ++ V K D WW+GE+ N QVG FP++YVK+
Sbjct: 127 VIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEV-----NGQVGLFPSNYVKL 178
Score = 50.4 bits (115), Expect = 4e-05
Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
I Y Y++ +L F G+ I V+ + D DWW G + + G+FPSNYV
Sbjct: 128 IGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYV 176
>AF248540-1|AAF63600.1| 1681|Homo sapiens intersectin 2 protein.
Length = 1681
Score = 146 bits (354), Expect = 5e-34
Identities = 74/152 (48%), Positives = 96/152 (63%), Gaps = 14/152 (9%)
Query: 1148 SGRDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQ 1207
S S +K EI Q ++Y A+ EQLSL GQL+++ KK SGWW+GELQA+G+ RQ
Sbjct: 1028 SASKSGASNKKPEIAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQ 1087
Query: 1208 VGWFPASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEK 1267
GWFPAS+VK+L G +S R TP + +V+A+Y Y A N DELSF K
Sbjct: 1088 KGWFPASHVKLL---GPSSERATPAFHP----------VCQVIAMYDYAANNEDELSFSK 1134
Query: 1268 DDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+I V ++ DP WWQGE+ G+ GLFPSNYV
Sbjct: 1135 GQLINVMNK-DDPDWWQGEINGVTGLFPSNYV 1165
Score = 128 bits (310), Expect = 1e-28
Identities = 120/395 (30%), Positives = 168/395 (42%), Gaps = 49/395 (12%)
Query: 134 QPSNQSLLGDFGSGQPLIQPLVQPVKPPVSTVPDLISGVKPLSQSLLDSPPMAPTVQPLI 193
+PS + GD L L PV + + DL K Q S M L
Sbjct: 45 KPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEF--SIAMKLIKLKLQ 102
Query: 194 GTVQPLIGPDPLMGS---VQPLIGSQPLAGPTPLVSSPQTLVNSSPLVSSQPIMSSQPLI 250
G P++ P P+M PLI ++ G P +S PQ L ++P+ S +SS
Sbjct: 103 GQQLPVVLP-PIMKQPPMFSPLISARFGMGSMPNLSIPQPLPPAAPITS----LSS---- 153
Query: 251 SASTISAQPLGTMQPLIGTAPP--IMGATQALIQSPPLSGPQQPAPVTAASFGGXXXXXX 308
+ S + PL PL+ + + T +LIQ PL P P ++++
Sbjct: 154 ATSGTNLPPLMMPTPLVPSVSTSSLPNGTASLIQ--PL-----PIPYSSSTLPHGSSYSL 206
Query: 309 XXXXXXGQPVTSTPIAALNKEVISKPGSVVTSPEVPMGVMSPPP--MEWGVPQPQKLKYT 366
G + + +I S TS + SP EW VPQP +LKY
Sbjct: 207 MMGGFGGASIQKA------QSLIDLGSSSSTSSTASLSGNSPKTGTSEWAVPQPTRLKYR 260
Query: 367 QLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLGCEEFVLAMYLC 426
Q FN D++ +G SG QAR+ +LQS L Q LA IW LAD+D DG+L EEF+LAM+L
Sbjct: 261 QKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHLT 320
Query: 427 EKATQGEPVPARLPPELIPPXXXXXXXXXXXXXX------------------XXXXXRRE 468
+ A G+P+P LPPEL+PP R+
Sbjct: 321 DMAKAGQPLPLTLPPELVPPSFRGGKQIDSINGTLPSYQKMQEEEPQKKLPVTFEDKRKA 380
Query: 469 NMARGQAELERRRTQLADAQMKEKVRGRGLNQSQW 503
N RG ELE+RR L + Q +E R + +W
Sbjct: 381 NYERGNMELEKRRQALMEQQQREAERKAQKEKEEW 415
Score = 103 bits (248), Expect = 3e-21
Identities = 46/86 (53%), Positives = 60/86 (69%)
Query: 6 WTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLD 65
W I + E K F NL P G +TG+QA+ F LQS LP PVL +IW+L+D N DGK+D
Sbjct: 27 WAITSEERTKHDRQFDNLKPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMD 86
Query: 66 LKEFSIACKIINLKLRGLEVPKMLPP 91
+EFSIA K+I LKL+G ++P +LPP
Sbjct: 87 QQEFSIAMKLIKLKLQGQQLPVVLPP 112
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/302 (25%), Positives = 134/302 (44%), Gaps = 35/302 (11%)
Query: 1004 YIASYPYSSSEPGDLVFEAGERIEVVRR---DGDWWTGRIGARTGIFPSNYVSREAAPAA 1060
Y A YP+ + ++ F +G+ I+V + + W G G FP NYV E P++
Sbjct: 746 YRALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYV--EKMPSS 803
Query: 1061 TSXXXXXXXXXXXXXXXXXXXXXXTSPPNTTPPIPASQLIWTSNELAYTSVTFLLAQDQK 1120
+ +S P ++ PAS + ++++++T + +K
Sbjct: 804 ENEKAVSPKKALLPPTVSLSATSTSSEPLSSNQ-PAS--VTDYQNVSFSNLTVNTSWQKK 860
Query: 1121 SSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRRKHEIVQALASYTATSPEQLSLMK 1180
S+ + ++ G+ V K QAL S+TA L+ K
Sbjct: 861 SAFTRTVSPGSVSPIH------------GQGQVVENLK---AQALCSWTAKKDNHLNFSK 905
Query: 1181 GQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRTTPVLSSKMDAL 1240
++ V ++ ++ WW GE+ GR GWFP SYVK++ S L + ++
Sbjct: 906 HDIITVLEQQEN-WWFGEVHG-GR----GWFPKSYVKIIPGS-EVKREEPEALYAAVNKK 958
Query: 1241 PTE---TVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSN 1297
PT +V ++ +ALYPY++ +L+F + + I VT + D WW G + G+FPSN
Sbjct: 959 PTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILVTQK--DGEWWTGSIGDRSGIFPSN 1016
Query: 1298 YV 1299
YV
Sbjct: 1017 YV 1018
Score = 87.0 bits (206), Expect = 4e-16
Identities = 47/85 (55%), Positives = 54/85 (63%), Gaps = 4/85 (4%)
Query: 968 VPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIE 1027
+P E + AL A V+ T S SV GE YIA YPYSS EPGDL F GE I
Sbjct: 938 IPGSEVKREEPEALYAAVNKKPT-SAAYSV---GEEYIALYPYSSVEPGDLTFTEGEEIL 993
Query: 1028 VVRRDGDWWTGRIGARTGIFPSNYV 1052
V ++DG+WWTG IG R+GIFPSNYV
Sbjct: 994 VTQKDGEWWTGSIGDRSGIFPSNYV 1018
Score = 62.9 bits (146), Expect = 7e-09
Identities = 31/90 (34%), Positives = 49/90 (54%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F L ++G L+G QA+ +LQS L L IW+LAD + DG+L
Sbjct: 249 WAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQL 308
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A + ++ G +P LPP L+
Sbjct: 309 KAEEFILAMHLTDMAKAGQPLPLTLPPELV 338
Score = 57.6 bits (133), Expect = 3e-07
Identities = 27/62 (43%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
Query: 1242 TETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRS-QDPAWWQGELRGMVGLFPSNYVT 1300
T +V+ ALYP+ A+N DE+SF DII V +++ +P W G +G G FP NYV
Sbjct: 739 TASVLVNYRALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVE 798
Query: 1301 KL 1302
K+
Sbjct: 799 KM 800
Score = 53.2 bits (122), Expect = 6e-06
Identities = 23/49 (46%), Positives = 31/49 (63%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDG-DWWTGRIGARTGIFPSNYV 1052
IA Y Y+++ +L F G+ I V+ +D DWW G I TG+FPSNYV
Sbjct: 1117 IAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYV 1165
Score = 49.6 bits (113), Expect = 7e-05
Identities = 71/337 (21%), Positives = 128/337 (37%), Gaps = 31/337 (9%)
Query: 633 QCQLEWEKKRTRELEALRSEEQSKVLSLKAKCQSLSAQLGAESVRCSTLAASIRDTRTAV 692
Q +LEWE+ R +EL ++ EQ +++ L +K ++L +L A + + ++ ++D R
Sbjct: 468 QRRLEWERIRRQELLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKK 527
Query: 693 AADKRTIDGMRSDRDSSMAE-------MQQLKARVKELNAKQIALNXXXXXXXXXXXXXX 745
K ++ + D + E +Q+ + ++ L ++ LN
Sbjct: 528 QTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQFSNTPDS 587
Query: 746 XXXXXXXXSMMEVTLKQ-LREKRPVMYDEVHSVV-EVDDLARCSLTLRARFIAVPATQVE 803
S+ + L Q L+E+ + E S + E+D LR + +E
Sbjct: 588 GVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKELRETY-NTQQLALE 646
Query: 804 AAKAIVESKTADLQHNEAQLAELNATVATLSDKC----EKVWK-------------LYEE 846
I K +++ +L + + K E +WK L EE
Sbjct: 647 QLYKIKRDKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEE 706
Query: 847 KRNEYIERRNTAPAEGTWGSSATETVQTAAPGGEGPQP-PRWRCVYPFVGRSADELSVQP 905
K E I+ E +T++ E +R +YPF R+ DE+S
Sbjct: 707 KTQEKIQEEERKAEEKQ--RKDKDTLKAEEKKRETASVLVNYRALYPFEARNHDEMSFNS 764
Query: 906 GDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESYVEDL 942
GD I+ +G GWFP +YVE +
Sbjct: 765 GD-IIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKM 800
>AF182199-1|AAF59904.1| 1248|Homo sapiens intersectin 2 short isoform
protein.
Length = 1248
Score = 146 bits (354), Expect = 5e-34
Identities = 74/152 (48%), Positives = 96/152 (63%), Gaps = 14/152 (9%)
Query: 1148 SGRDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQ 1207
S S +K EI Q ++Y A+ EQLSL GQL+++ KK SGWW+GELQA+G+ RQ
Sbjct: 1043 SASKSGASNKKPEIAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQ 1102
Query: 1208 VGWFPASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEK 1267
GWFPAS+VK+L G +S R TP + +V+A+Y Y A N DELSF K
Sbjct: 1103 KGWFPASHVKLL---GPSSERATPAFHP----------VCQVIAMYDYAANNEDELSFSK 1149
Query: 1268 DDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+I V ++ DP WWQGE+ G+ GLFPSNYV
Sbjct: 1150 GQLINVMNK-DDPDWWQGEINGVTGLFPSNYV 1180
Score = 128 bits (310), Expect = 1e-28
Identities = 120/395 (30%), Positives = 168/395 (42%), Gaps = 49/395 (12%)
Query: 134 QPSNQSLLGDFGSGQPLIQPLVQPVKPPVSTVPDLISGVKPLSQSLLDSPPMAPTVQPLI 193
+PS + GD L L PV + + DL K Q S M L
Sbjct: 33 KPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEF--SIAMKLIKLKLQ 90
Query: 194 GTVQPLIGPDPLMGS---VQPLIGSQPLAGPTPLVSSPQTLVNSSPLVSSQPIMSSQPLI 250
G P++ P P+M PLI ++ G P +S PQ L ++P+ S +SS
Sbjct: 91 GQQLPVVLP-PIMKQPPMFSPLISARFGMGSMPNLSIPQPLPPAAPITS----LSS---- 141
Query: 251 SASTISAQPLGTMQPLIGTAPP--IMGATQALIQSPPLSGPQQPAPVTAASFGGXXXXXX 308
+ S + PL PL+ + + T +LIQ PL P P ++++
Sbjct: 142 ATSGTNLPPLMMPTPLVPSVSTSSLPNGTASLIQ--PL-----PIPYSSSTLPHGSSYSL 194
Query: 309 XXXXXXGQPVTSTPIAALNKEVISKPGSVVTSPEVPMGVMSPPP--MEWGVPQPQKLKYT 366
G + + +I S TS + SP EW VPQP +LKY
Sbjct: 195 MMGGFGGASIQKA------QSLIDLGSSSSTSSTASLSGNSPKTGTSEWAVPQPTRLKYR 248
Query: 367 QLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLGCEEFVLAMYLC 426
Q FN D++ +G SG QAR+ +LQS L Q LA IW LAD+D DG+L EEF+LAM+L
Sbjct: 249 QKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHLT 308
Query: 427 EKATQGEPVPARLPPELIPPXXXXXXXXXXXXXX------------------XXXXXRRE 468
+ A G+P+P LPPEL+PP R+
Sbjct: 309 DMAKAGQPLPLTLPPELVPPSFRGGKQIDSINGTLPSYQKMQEEEPQKKLPVTFEDKRKA 368
Query: 469 NMARGQAELERRRTQLADAQMKEKVRGRGLNQSQW 503
N RG ELE+RR L + Q +E R + +W
Sbjct: 369 NYERGNMELEKRRQALMEQQQREAERKAQKEKEEW 403
Score = 103 bits (248), Expect = 3e-21
Identities = 46/86 (53%), Positives = 60/86 (69%)
Query: 6 WTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLD 65
W I + E K F NL P G +TG+QA+ F LQS LP PVL +IW+L+D N DGK+D
Sbjct: 15 WAITSEERTKHDRQFDNLKPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMD 74
Query: 66 LKEFSIACKIINLKLRGLEVPKMLPP 91
+EFSIA K+I LKL+G ++P +LPP
Sbjct: 75 QQEFSIAMKLIKLKLQGQQLPVVLPP 100
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/302 (25%), Positives = 134/302 (44%), Gaps = 35/302 (11%)
Query: 1004 YIASYPYSSSEPGDLVFEAGERIEVVRR---DGDWWTGRIGARTGIFPSNYVSREAAPAA 1060
Y A YP+ + ++ F +G+ I+V + + W G G FP NYV E P++
Sbjct: 761 YRALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYV--EKMPSS 818
Query: 1061 TSXXXXXXXXXXXXXXXXXXXXXXTSPPNTTPPIPASQLIWTSNELAYTSVTFLLAQDQK 1120
+ +S P ++ PAS + ++++++T + +K
Sbjct: 819 ENEKAVSPKKALLPPTVSLSATSTSSEPLSSNQ-PAS--VTDYQNVSFSNLTVNTSWQKK 875
Query: 1121 SSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRRKHEIVQALASYTATSPEQLSLMK 1180
S+ + ++ G+ V K QAL S+TA L+ K
Sbjct: 876 SAFTRTVSPGSVSPIH------------GQGQVVENLK---AQALCSWTAKKDNHLNFSK 920
Query: 1181 GQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRTTPVLSSKMDAL 1240
++ V ++ ++ WW GE+ GR GWFP SYVK++ S L + ++
Sbjct: 921 HDIITVLEQQEN-WWFGEVHG-GR----GWFPKSYVKIIPGS-EVKREEPEALYAAVNKK 973
Query: 1241 PTE---TVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSN 1297
PT +V ++ +ALYPY++ +L+F + + I VT + D WW G + G+FPSN
Sbjct: 974 PTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILVTQK--DGEWWTGSIGDRSGIFPSN 1031
Query: 1298 YV 1299
YV
Sbjct: 1032 YV 1033
Score = 87.0 bits (206), Expect = 4e-16
Identities = 47/85 (55%), Positives = 54/85 (63%), Gaps = 4/85 (4%)
Query: 968 VPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIE 1027
+P E + AL A V+ T S SV GE YIA YPYSS EPGDL F GE I
Sbjct: 953 IPGSEVKREEPEALYAAVNKKPT-SAAYSV---GEEYIALYPYSSVEPGDLTFTEGEEIL 1008
Query: 1028 VVRRDGDWWTGRIGARTGIFPSNYV 1052
V ++DG+WWTG IG R+GIFPSNYV
Sbjct: 1009 VTQKDGEWWTGSIGDRSGIFPSNYV 1033
Score = 62.9 bits (146), Expect = 7e-09
Identities = 31/90 (34%), Positives = 49/90 (54%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F L ++G L+G QA+ +LQS L L IW+LAD + DG+L
Sbjct: 237 WAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQL 296
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A + ++ G +P LPP L+
Sbjct: 297 KAEEFILAMHLTDMAKAGQPLPLTLPPELV 326
Score = 57.6 bits (133), Expect = 3e-07
Identities = 27/62 (43%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
Query: 1242 TETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRS-QDPAWWQGELRGMVGLFPSNYVT 1300
T +V+ ALYP+ A+N DE+SF DII V +++ +P W G +G G FP NYV
Sbjct: 754 TASVLVNYRALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVE 813
Query: 1301 KL 1302
K+
Sbjct: 814 KM 815
Score = 53.2 bits (122), Expect = 6e-06
Identities = 23/49 (46%), Positives = 31/49 (63%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDG-DWWTGRIGARTGIFPSNYV 1052
IA Y Y+++ +L F G+ I V+ +D DWW G I TG+FPSNYV
Sbjct: 1132 IAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYV 1180
Score = 39.5 bits (88), Expect = 0.077
Identities = 30/106 (28%), Positives = 43/106 (40%), Gaps = 4/106 (3%)
Query: 838 EKVWKLYEEKRNEYIERRNTAPAEGTWGSSATETVQTAAPGGEGPQP-PRWRCVYPFVGR 896
EK +L EEK E I+ E +T++ E +R +YPF R
Sbjct: 713 EKQKRLQEEKTQEKIQEEERKAEEKQ--RKDKDTLKAEEKKRETASVLVNYRALYPFEAR 770
Query: 897 SADELSVQPGDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESYVEDL 942
+ DE+S GD I+ +G GWFP +YVE +
Sbjct: 771 NHDEMSFNSGD-IIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKM 815
>AF182198-1|AAF59903.1| 1696|Homo sapiens intersectin 2 long isoform
protein.
Length = 1696
Score = 146 bits (354), Expect = 5e-34
Identities = 74/152 (48%), Positives = 96/152 (63%), Gaps = 14/152 (9%)
Query: 1148 SGRDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQ 1207
S S +K EI Q ++Y A+ EQLSL GQL+++ KK SGWW+GELQA+G+ RQ
Sbjct: 1043 SASKSGASNKKPEIAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQ 1102
Query: 1208 VGWFPASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEK 1267
GWFPAS+VK+L G +S R TP + +V+A+Y Y A N DELSF K
Sbjct: 1103 KGWFPASHVKLL---GPSSERATPAFHP----------VCQVIAMYDYAANNEDELSFSK 1149
Query: 1268 DDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+I V ++ DP WWQGE+ G+ GLFPSNYV
Sbjct: 1150 GQLINVMNK-DDPDWWQGEINGVTGLFPSNYV 1180
Score = 128 bits (310), Expect = 1e-28
Identities = 120/395 (30%), Positives = 168/395 (42%), Gaps = 49/395 (12%)
Query: 134 QPSNQSLLGDFGSGQPLIQPLVQPVKPPVSTVPDLISGVKPLSQSLLDSPPMAPTVQPLI 193
+PS + GD L L PV + + DL K Q S M L
Sbjct: 33 KPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEF--SIAMKLIKLKLQ 90
Query: 194 GTVQPLIGPDPLMGS---VQPLIGSQPLAGPTPLVSSPQTLVNSSPLVSSQPIMSSQPLI 250
G P++ P P+M PLI ++ G P +S PQ L ++P+ S +SS
Sbjct: 91 GQQLPVVLP-PIMKQPPMFSPLISARFGMGSMPNLSIPQPLPPAAPITS----LSS---- 141
Query: 251 SASTISAQPLGTMQPLIGTAPP--IMGATQALIQSPPLSGPQQPAPVTAASFGGXXXXXX 308
+ S + PL PL+ + + T +LIQ PL P P ++++
Sbjct: 142 ATSGTNLPPLMMPTPLVPSVSTSSLPNGTASLIQ--PL-----PIPYSSSTLPHGSSYSL 194
Query: 309 XXXXXXGQPVTSTPIAALNKEVISKPGSVVTSPEVPMGVMSPPP--MEWGVPQPQKLKYT 366
G + + +I S TS + SP EW VPQP +LKY
Sbjct: 195 MMGGFGGASIQKA------QSLIDLGSSSSTSSTASLSGNSPKTGTSEWAVPQPTRLKYR 248
Query: 367 QLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLGCEEFVLAMYLC 426
Q FN D++ +G SG QAR+ +LQS L Q LA IW LAD+D DG+L EEF+LAM+L
Sbjct: 249 QKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHLT 308
Query: 427 EKATQGEPVPARLPPELIPPXXXXXXXXXXXXXX------------------XXXXXRRE 468
+ A G+P+P LPPEL+PP R+
Sbjct: 309 DMAKAGQPLPLTLPPELVPPSFRGGKQIDSINGTLPSYQKMQEEEPQKKLPVTFEDKRKA 368
Query: 469 NMARGQAELERRRTQLADAQMKEKVRGRGLNQSQW 503
N RG ELE+RR L + Q +E R + +W
Sbjct: 369 NYERGNMELEKRRQALMEQQQREAERKAQKEKEEW 403
Score = 103 bits (248), Expect = 3e-21
Identities = 46/86 (53%), Positives = 60/86 (69%)
Query: 6 WTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLD 65
W I + E K F NL P G +TG+QA+ F LQS LP PVL +IW+L+D N DGK+D
Sbjct: 15 WAITSEERTKHDRQFDNLKPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMD 74
Query: 66 LKEFSIACKIINLKLRGLEVPKMLPP 91
+EFSIA K+I LKL+G ++P +LPP
Sbjct: 75 QQEFSIAMKLIKLKLQGQQLPVVLPP 100
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/302 (25%), Positives = 134/302 (44%), Gaps = 35/302 (11%)
Query: 1004 YIASYPYSSSEPGDLVFEAGERIEVVRR---DGDWWTGRIGARTGIFPSNYVSREAAPAA 1060
Y A YP+ + ++ F +G+ I+V + + W G G FP NYV E P++
Sbjct: 761 YRALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYV--EKMPSS 818
Query: 1061 TSXXXXXXXXXXXXXXXXXXXXXXTSPPNTTPPIPASQLIWTSNELAYTSVTFLLAQDQK 1120
+ +S P ++ PAS + ++++++T + +K
Sbjct: 819 ENEKAVSPKKALLPPTVSLSATSTSSEPLSSNQ-PAS--VTDYQNVSFSNLTVNTSWQKK 875
Query: 1121 SSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRRKHEIVQALASYTATSPEQLSLMK 1180
S+ + ++ G+ V K QAL S+TA L+ K
Sbjct: 876 SAFTRTVSPGSVSPIH------------GQGQVVENLK---AQALCSWTAKKDNHLNFSK 920
Query: 1181 GQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRTTPVLSSKMDAL 1240
++ V ++ ++ WW GE+ GR GWFP SYVK++ S L + ++
Sbjct: 921 HDIITVLEQQEN-WWFGEVHG-GR----GWFPKSYVKIIPGS-EVKREEPEALYAAVNKK 973
Query: 1241 PTE---TVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSN 1297
PT +V ++ +ALYPY++ +L+F + + I VT + D WW G + G+FPSN
Sbjct: 974 PTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILVTQK--DGEWWTGSIGDRSGIFPSN 1031
Query: 1298 YV 1299
YV
Sbjct: 1032 YV 1033
Score = 87.0 bits (206), Expect = 4e-16
Identities = 47/85 (55%), Positives = 54/85 (63%), Gaps = 4/85 (4%)
Query: 968 VPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIE 1027
+P E + AL A V+ T S SV GE YIA YPYSS EPGDL F GE I
Sbjct: 953 IPGSEVKREEPEALYAAVNKKPT-SAAYSV---GEEYIALYPYSSVEPGDLTFTEGEEIL 1008
Query: 1028 VVRRDGDWWTGRIGARTGIFPSNYV 1052
V ++DG+WWTG IG R+GIFPSNYV
Sbjct: 1009 VTQKDGEWWTGSIGDRSGIFPSNYV 1033
Score = 62.9 bits (146), Expect = 7e-09
Identities = 31/90 (34%), Positives = 49/90 (54%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F L ++G L+G QA+ +LQS L L IW+LAD + DG+L
Sbjct: 237 WAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQL 296
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A + ++ G +P LPP L+
Sbjct: 297 KAEEFILAMHLTDMAKAGQPLPLTLPPELV 326
Score = 57.6 bits (133), Expect = 3e-07
Identities = 27/62 (43%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
Query: 1242 TETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRS-QDPAWWQGELRGMVGLFPSNYVT 1300
T +V+ ALYP+ A+N DE+SF DII V +++ +P W G +G G FP NYV
Sbjct: 754 TASVLVNYRALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVE 813
Query: 1301 KL 1302
K+
Sbjct: 814 KM 815
Score = 53.2 bits (122), Expect = 6e-06
Identities = 23/49 (46%), Positives = 31/49 (63%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDG-DWWTGRIGARTGIFPSNYV 1052
IA Y Y+++ +L F G+ I V+ +D DWW G I TG+FPSNYV
Sbjct: 1132 IAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYV 1180
Score = 39.5 bits (88), Expect = 0.077
Identities = 30/106 (28%), Positives = 43/106 (40%), Gaps = 4/106 (3%)
Query: 838 EKVWKLYEEKRNEYIERRNTAPAEGTWGSSATETVQTAAPGGEGPQP-PRWRCVYPFVGR 896
EK +L EEK E I+ E +T++ E +R +YPF R
Sbjct: 713 EKQKRLQEEKTQEKIQEEERKAEEKQ--RKDKDTLKAEEKKRETASVLVNYRALYPFEAR 770
Query: 897 SADELSVQPGDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESYVEDL 942
+ DE+S GD I+ +G GWFP +YVE +
Sbjct: 771 NHDEMSFNSGD-IIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKM 815
>AF001630-1|AAD00899.1| 464|Homo sapiens SH3P18-like WASP associated
protein protein.
Length = 464
Score = 146 bits (354), Expect = 5e-34
Identities = 74/152 (48%), Positives = 96/152 (63%), Gaps = 14/152 (9%)
Query: 1148 SGRDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQ 1207
S S +K EI Q ++Y A+ EQLSL GQL+++ KK SGWW+GELQA+G+ RQ
Sbjct: 223 SASKSGASNKKPEIAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQ 282
Query: 1208 VGWFPASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEK 1267
GWFPAS+VK+L G +S R TP + +V+A+Y Y A N DELSF K
Sbjct: 283 KGWFPASHVKLL---GPSSERATPAFHP----------VCQVIAMYDYAANNEDELSFSK 329
Query: 1268 DDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+I V ++ DP WWQGE+ G+ GLFPSNYV
Sbjct: 330 GQLINVMNK-DDPDWWQGEINGVTGLFPSNYV 360
Score = 87.0 bits (206), Expect = 4e-16
Identities = 47/85 (55%), Positives = 54/85 (63%), Gaps = 4/85 (4%)
Query: 968 VPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIE 1027
+P E + AL A V+ T S SV GE YIA YPYSS EPGDL F GE I
Sbjct: 133 IPGSEVKREEPEALYAAVNKKPT-SAAYSV---GEEYIALYPYSSVEPGDLTFTEGEEIL 188
Query: 1028 VVRRDGDWWTGRIGARTGIFPSNYV 1052
V ++DG+WWTG IG R+GIFPSNYV
Sbjct: 189 VTQKDGEWWTGSIGDRSGIFPSNYV 213
Score = 83.8 bits (198), Expect = 4e-15
Identities = 49/140 (35%), Positives = 76/140 (54%), Gaps = 12/140 (8%)
Query: 1163 QALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSS 1222
QAL S+TA L+ K ++ V ++ ++ WW GE+ GR GWFP SYVK++ S
Sbjct: 83 QALCSWTAKKDNHLNFSKHDIITVLEQQEN-WWFGEVHG-GR----GWFPKSYVKIIPGS 136
Query: 1223 GRTSGRTTPVLSSKMDALPTE---TVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQD 1279
L + ++ PT +V ++ +ALYPY++ +L+F + + I VT + D
Sbjct: 137 -EVKREEPEALYAAVNKKPTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILVTQK--D 193
Query: 1280 PAWWQGELRGMVGLFPSNYV 1299
WW G + G+FPSNYV
Sbjct: 194 GEWWTGSIGDRSGIFPSNYV 213
Score = 53.2 bits (122), Expect = 6e-06
Identities = 23/49 (46%), Positives = 31/49 (63%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDG-DWWTGRIGARTGIFPSNYV 1052
IA Y Y+++ +L F G+ I V+ +D DWW G I TG+FPSNYV
Sbjct: 312 IAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYV 360
Score = 46.0 bits (104), Expect = 9e-04
Identities = 22/52 (42%), Positives = 32/52 (61%), Gaps = 2/52 (3%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
K AL +TA+ + L+F K DII V ++ ++ WW GE+ G G FP +YV
Sbjct: 81 KAQALCSWTAKKDNHLNFSKHDIITVLEQQEN--WWFGEVHGGRGWFPKSYV 130
>AC009228-1|AAX93122.1| 1329|Homo sapiens unknown protein.
Length = 1329
Score = 146 bits (354), Expect = 5e-34
Identities = 74/152 (48%), Positives = 96/152 (63%), Gaps = 14/152 (9%)
Query: 1148 SGRDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQ 1207
S S +K EI Q ++Y A+ EQLSL GQL+++ KK SGWW+GELQA+G+ RQ
Sbjct: 1043 SASKSGASNKKPEIAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQ 1102
Query: 1208 VGWFPASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEK 1267
GWFPAS+VK+L G +S R TP + +V+A+Y Y A N DELSF K
Sbjct: 1103 KGWFPASHVKLL---GPSSERATPAFHP----------VCQVIAMYDYAANNEDELSFSK 1149
Query: 1268 DDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+I V ++ DP WWQGE+ G+ GLFPSNYV
Sbjct: 1150 GQLINVMNK-DDPDWWQGEINGVTGLFPSNYV 1180
Score = 128 bits (310), Expect = 1e-28
Identities = 120/395 (30%), Positives = 168/395 (42%), Gaps = 49/395 (12%)
Query: 134 QPSNQSLLGDFGSGQPLIQPLVQPVKPPVSTVPDLISGVKPLSQSLLDSPPMAPTVQPLI 193
+PS + GD L L PV + + DL K Q S M L
Sbjct: 33 KPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEF--SIAMKLIKLKLQ 90
Query: 194 GTVQPLIGPDPLMGS---VQPLIGSQPLAGPTPLVSSPQTLVNSSPLVSSQPIMSSQPLI 250
G P++ P P+M PLI ++ G P +S PQ L ++P+ S +SS
Sbjct: 91 GQQLPVVLP-PIMKQPPMFSPLISARFGMGSMPNLSIPQPLPPAAPITS----LSS---- 141
Query: 251 SASTISAQPLGTMQPLIGTAPP--IMGATQALIQSPPLSGPQQPAPVTAASFGGXXXXXX 308
+ S + PL PL+ + + T +LIQ PL P P ++++
Sbjct: 142 ATSGTNLPPLMMPTPLVPSVSTSSLPNGTASLIQ--PL-----PIPYSSSTLPHGSSYSL 194
Query: 309 XXXXXXGQPVTSTPIAALNKEVISKPGSVVTSPEVPMGVMSPPP--MEWGVPQPQKLKYT 366
G + + +I S TS + SP EW VPQP +LKY
Sbjct: 195 MMGGFGGASIQKA------QSLIDLGSSSSTSSTASLSGNSPKTGTSEWAVPQPTRLKYR 248
Query: 367 QLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLGCEEFVLAMYLC 426
Q FN D++ +G SG QAR+ +LQS L Q LA IW LAD+D DG+L EEF+LAM+L
Sbjct: 249 QKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHLT 308
Query: 427 EKATQGEPVPARLPPELIPPXXXXXXXXXXXXXX------------------XXXXXRRE 468
+ A G+P+P LPPEL+PP R+
Sbjct: 309 DMAKAGQPLPLTLPPELVPPSFRGGKQIDSINGTLPSYQKMQEEEPQKKLPVTFEDKRKA 368
Query: 469 NMARGQAELERRRTQLADAQMKEKVRGRGLNQSQW 503
N RG ELE+RR L + Q +E R + +W
Sbjct: 369 NYERGNMELEKRRQALMEQQQREAERKAQKEKEEW 403
Score = 103 bits (248), Expect = 3e-21
Identities = 46/86 (53%), Positives = 60/86 (69%)
Query: 6 WTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLD 65
W I + E K F NL P G +TG+QA+ F LQS LP PVL +IW+L+D N DGK+D
Sbjct: 15 WAITSEERTKHDRQFDNLKPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMD 74
Query: 66 LKEFSIACKIINLKLRGLEVPKMLPP 91
+EFSIA K+I LKL+G ++P +LPP
Sbjct: 75 QQEFSIAMKLIKLKLQGQQLPVVLPP 100
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/302 (25%), Positives = 134/302 (44%), Gaps = 35/302 (11%)
Query: 1004 YIASYPYSSSEPGDLVFEAGERIEVVRR---DGDWWTGRIGARTGIFPSNYVSREAAPAA 1060
Y A YP+ + ++ F +G+ I+V + + W G G FP NYV E P++
Sbjct: 761 YRALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYV--EKMPSS 818
Query: 1061 TSXXXXXXXXXXXXXXXXXXXXXXTSPPNTTPPIPASQLIWTSNELAYTSVTFLLAQDQK 1120
+ +S P ++ PAS + ++++++T + +K
Sbjct: 819 ENEKAVSPKKALLPPTVSLSATSTSSEPLSSNQ-PAS--VTDYQNVSFSNLTVNTSWQKK 875
Query: 1121 SSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRRKHEIVQALASYTATSPEQLSLMK 1180
S+ + ++ G+ V K QAL S+TA L+ K
Sbjct: 876 SAFTRTVSPGSVSPIH------------GQGQVVENLK---AQALCSWTAKKDNHLNFSK 920
Query: 1181 GQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRTTPVLSSKMDAL 1240
++ V ++ ++ WW GE+ GR GWFP SYVK++ S L + ++
Sbjct: 921 HDIITVLEQQEN-WWFGEVHG-GR----GWFPKSYVKIIPGS-EVKREEPEALYAAVNKK 973
Query: 1241 PTE---TVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSN 1297
PT +V ++ +ALYPY++ +L+F + + I VT + D WW G + G+FPSN
Sbjct: 974 PTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILVTQK--DGEWWTGSIGDRSGIFPSN 1031
Query: 1298 YV 1299
YV
Sbjct: 1032 YV 1033
Score = 87.0 bits (206), Expect = 4e-16
Identities = 47/85 (55%), Positives = 54/85 (63%), Gaps = 4/85 (4%)
Query: 968 VPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIE 1027
+P E + AL A V+ T S SV GE YIA YPYSS EPGDL F GE I
Sbjct: 953 IPGSEVKREEPEALYAAVNKKPT-SAAYSV---GEEYIALYPYSSVEPGDLTFTEGEEIL 1008
Query: 1028 VVRRDGDWWTGRIGARTGIFPSNYV 1052
V ++DG+WWTG IG R+GIFPSNYV
Sbjct: 1009 VTQKDGEWWTGSIGDRSGIFPSNYV 1033
Score = 62.9 bits (146), Expect = 7e-09
Identities = 31/90 (34%), Positives = 49/90 (54%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F L ++G L+G QA+ +LQS L L IW+LAD + DG+L
Sbjct: 237 WAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQL 296
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A + ++ G +P LPP L+
Sbjct: 297 KAEEFILAMHLTDMAKAGQPLPLTLPPELV 326
Score = 57.6 bits (133), Expect = 3e-07
Identities = 27/62 (43%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
Query: 1242 TETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRS-QDPAWWQGELRGMVGLFPSNYVT 1300
T +V+ ALYP+ A+N DE+SF DII V +++ +P W G +G G FP NYV
Sbjct: 754 TASVLVNYRALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVE 813
Query: 1301 KL 1302
K+
Sbjct: 814 KM 815
Score = 53.2 bits (122), Expect = 6e-06
Identities = 23/49 (46%), Positives = 31/49 (63%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDG-DWWTGRIGARTGIFPSNYV 1052
IA Y Y+++ +L F G+ I V+ +D DWW G I TG+FPSNYV
Sbjct: 1132 IAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYV 1180
Score = 39.5 bits (88), Expect = 0.077
Identities = 30/106 (28%), Positives = 43/106 (40%), Gaps = 4/106 (3%)
Query: 838 EKVWKLYEEKRNEYIERRNTAPAEGTWGSSATETVQTAAPGGEGPQP-PRWRCVYPFVGR 896
EK +L EEK E I+ E +T++ E +R +YPF R
Sbjct: 713 EKQKRLQEEKTQEKIQEEERKAEEKQ--RKDKDTLKAEEKKRETASVLVNYRALYPFEAR 770
Query: 897 SADELSVQPGDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESYVEDL 942
+ DE+S GD I+ +G GWFP +YVE +
Sbjct: 771 NHDEMSFNSGD-IIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKM 815
>AB033082-1|BAA86570.1| 1676|Homo sapiens KIAA1256 protein protein.
Length = 1676
Score = 146 bits (354), Expect = 5e-34
Identities = 74/152 (48%), Positives = 96/152 (63%), Gaps = 14/152 (9%)
Query: 1148 SGRDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQ 1207
S S +K EI Q ++Y A+ EQLSL GQL+++ KK SGWW+GELQA+G+ RQ
Sbjct: 1023 SASKSGASNKKPEIAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQ 1082
Query: 1208 VGWFPASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEK 1267
GWFPAS+VK+L G +S R TP + +V+A+Y Y A N DELSF K
Sbjct: 1083 KGWFPASHVKLL---GPSSERATPAFHP----------VCQVIAMYDYAANNEDELSFSK 1129
Query: 1268 DDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+I V ++ DP WWQGE+ G+ GLFPSNYV
Sbjct: 1130 GQLINVMNK-DDPDWWQGEINGVTGLFPSNYV 1160
Score = 128 bits (310), Expect = 1e-28
Identities = 120/395 (30%), Positives = 168/395 (42%), Gaps = 49/395 (12%)
Query: 134 QPSNQSLLGDFGSGQPLIQPLVQPVKPPVSTVPDLISGVKPLSQSLLDSPPMAPTVQPLI 193
+PS + GD L L PV + + DL K Q S M L
Sbjct: 40 KPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEF--SIAMKLIKLKLQ 97
Query: 194 GTVQPLIGPDPLMGS---VQPLIGSQPLAGPTPLVSSPQTLVNSSPLVSSQPIMSSQPLI 250
G P++ P P+M PLI ++ G P +S PQ L ++P+ S +SS
Sbjct: 98 GQQLPVVLP-PIMKQPPMFSPLISARFGMGSMPNLSIPQPLPPAAPITS----LSS---- 148
Query: 251 SASTISAQPLGTMQPLIGTAPP--IMGATQALIQSPPLSGPQQPAPVTAASFGGXXXXXX 308
+ S + PL PL+ + + T +LIQ PL P P ++++
Sbjct: 149 ATSGTNLPPLMMPTPLVPSVSTSSLPNGTASLIQ--PL-----PIPYSSSTLPHGSSYSL 201
Query: 309 XXXXXXGQPVTSTPIAALNKEVISKPGSVVTSPEVPMGVMSPPP--MEWGVPQPQKLKYT 366
G + + +I S TS + SP EW VPQP +LKY
Sbjct: 202 MMGGFGGASIQKA------QSLIDLGSSSSTSSTASLSGNSPKTGTSEWAVPQPTRLKYR 255
Query: 367 QLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLGCEEFVLAMYLC 426
Q FN D++ +G SG QAR+ +LQS L Q LA IW LAD+D DG+L EEF+LAM+L
Sbjct: 256 QKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHLT 315
Query: 427 EKATQGEPVPARLPPELIPPXXXXXXXXXXXXXX------------------XXXXXRRE 468
+ A G+P+P LPPEL+PP R+
Sbjct: 316 DMAKAGQPLPLTLPPELVPPSFRGGKQIDSINGTLPSYQKMQEEEPQKKLPVTFEDKRKA 375
Query: 469 NMARGQAELERRRTQLADAQMKEKVRGRGLNQSQW 503
N RG ELE+RR L + Q +E R + +W
Sbjct: 376 NYERGNMELEKRRQALMEQQQREAERKAQKEKEEW 410
Score = 103 bits (248), Expect = 3e-21
Identities = 46/86 (53%), Positives = 60/86 (69%)
Query: 6 WTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLD 65
W I + E K F NL P G +TG+QA+ F LQS LP PVL +IW+L+D N DGK+D
Sbjct: 22 WAITSEERTKHDRQFDNLKPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMD 81
Query: 66 LKEFSIACKIINLKLRGLEVPKMLPP 91
+EFSIA K+I LKL+G ++P +LPP
Sbjct: 82 QQEFSIAMKLIKLKLQGQQLPVVLPP 107
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/302 (25%), Positives = 134/302 (44%), Gaps = 35/302 (11%)
Query: 1004 YIASYPYSSSEPGDLVFEAGERIEVVRR---DGDWWTGRIGARTGIFPSNYVSREAAPAA 1060
Y A YP+ + ++ F +G+ I+V + + W G G FP NYV E P++
Sbjct: 741 YRALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYV--EKMPSS 798
Query: 1061 TSXXXXXXXXXXXXXXXXXXXXXXTSPPNTTPPIPASQLIWTSNELAYTSVTFLLAQDQK 1120
+ +S P ++ PAS + ++++++T + +K
Sbjct: 799 ENEKAVSPKKALLPPTVSLSATSTSSEPLSSNQ-PAS--VTDYQNVSFSNLTVNTSWQKK 855
Query: 1121 SSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRRKHEIVQALASYTATSPEQLSLMK 1180
S+ + ++ G+ V K QAL S+TA L+ K
Sbjct: 856 SAFTRTVSPGSVSPIH------------GQGQVVENLK---AQALCSWTAKKDNHLNFSK 900
Query: 1181 GQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRTTPVLSSKMDAL 1240
++ V ++ ++ WW GE+ GR GWFP SYVK++ S L + ++
Sbjct: 901 HDIITVLEQQEN-WWFGEVHG-GR----GWFPKSYVKIIPGS-EVKREEPEALYAAVNKK 953
Query: 1241 PTE---TVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSN 1297
PT +V ++ +ALYPY++ +L+F + + I VT + D WW G + G+FPSN
Sbjct: 954 PTSAAYSVGEEYIALYPYSSVEPGDLTFTEGEEILVTQK--DGEWWTGSIGDRSGIFPSN 1011
Query: 1298 YV 1299
YV
Sbjct: 1012 YV 1013
Score = 87.0 bits (206), Expect = 4e-16
Identities = 47/85 (55%), Positives = 54/85 (63%), Gaps = 4/85 (4%)
Query: 968 VPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIE 1027
+P E + AL A V+ T S SV GE YIA YPYSS EPGDL F GE I
Sbjct: 933 IPGSEVKREEPEALYAAVNKKPT-SAAYSV---GEEYIALYPYSSVEPGDLTFTEGEEIL 988
Query: 1028 VVRRDGDWWTGRIGARTGIFPSNYV 1052
V ++DG+WWTG IG R+GIFPSNYV
Sbjct: 989 VTQKDGEWWTGSIGDRSGIFPSNYV 1013
Score = 62.9 bits (146), Expect = 7e-09
Identities = 31/90 (34%), Positives = 49/90 (54%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F L ++G L+G QA+ +LQS L L IW+LAD + DG+L
Sbjct: 244 WAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQL 303
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A + ++ G +P LPP L+
Sbjct: 304 KAEEFILAMHLTDMAKAGQPLPLTLPPELV 333
Score = 57.6 bits (133), Expect = 3e-07
Identities = 27/62 (43%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
Query: 1242 TETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRS-QDPAWWQGELRGMVGLFPSNYVT 1300
T +V+ ALYP+ A+N DE+SF DII V +++ +P W G +G G FP NYV
Sbjct: 734 TASVLVNYRALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVE 793
Query: 1301 KL 1302
K+
Sbjct: 794 KM 795
Score = 53.2 bits (122), Expect = 6e-06
Identities = 23/49 (46%), Positives = 31/49 (63%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDG-DWWTGRIGARTGIFPSNYV 1052
IA Y Y+++ +L F G+ I V+ +D DWW G I TG+FPSNYV
Sbjct: 1112 IAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYV 1160
Score = 49.6 bits (113), Expect = 7e-05
Identities = 71/337 (21%), Positives = 128/337 (37%), Gaps = 31/337 (9%)
Query: 633 QCQLEWEKKRTRELEALRSEEQSKVLSLKAKCQSLSAQLGAESVRCSTLAASIRDTRTAV 692
Q +LEWE+ R +EL ++ EQ +++ L +K ++L +L A + + ++ ++D R
Sbjct: 463 QRRLEWERIRRQELLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKK 522
Query: 693 AADKRTIDGMRSDRDSSMAE-------MQQLKARVKELNAKQIALNXXXXXXXXXXXXXX 745
K ++ + D + E +Q+ + ++ L ++ LN
Sbjct: 523 QTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQFSNTPDS 582
Query: 746 XXXXXXXXSMMEVTLKQ-LREKRPVMYDEVHSVV-EVDDLARCSLTLRARFIAVPATQVE 803
S+ + L Q L+E+ + E S + E+D LR + +E
Sbjct: 583 GVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKELRETY-NTQQLALE 641
Query: 804 AAKAIVESKTADLQHNEAQLAELNATVATLSDKC----EKVWK-------------LYEE 846
I K +++ +L + + K E +WK L EE
Sbjct: 642 QLYKIKRDKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEE 701
Query: 847 KRNEYIERRNTAPAEGTWGSSATETVQTAAPGGEGPQP-PRWRCVYPFVGRSADELSVQP 905
K E I+ E +T++ E +R +YPF R+ DE+S
Sbjct: 702 KTQEKIQEEERKAEEKQ--RKDKDTLKAEEKKRETASVLVNYRALYPFEARNHDEMSFNS 759
Query: 906 GDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESYVEDL 942
GD I+ +G GWFP +YVE +
Sbjct: 760 GD-IIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKM 795
>DQ386455-1|ABD72328.1| 1020|Homo sapiens intersectin 1 short form
transcript variant 8 protein.
Length = 1020
Score = 134 bits (323), Expect = 3e-30
Identities = 82/211 (38%), Positives = 110/211 (52%), Gaps = 10/211 (4%)
Query: 242 PIMSSQPLI--SASTISAQPLGTMQPLIGTAPPIMGATQALIQSPPLSGPQQPAPVTAAS 299
P+M QP+ SA + +M PL AP MG+ + SP L A V +
Sbjct: 100 PVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLA 159
Query: 300 FGGXXXXXXXXXXXXGQPVTSTPIAALNKEVISKPGSVVTSP---EVPMGVMSPPPM-EW 355
G P + P ++ S PGS + + V S PP+ EW
Sbjct: 160 NGAPPVIQPLPAFA--HPAATLPKSSSFSR--SGPGSQLNTKLQKAQSFDVASVPPVAEW 215
Query: 356 GVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLG 415
VPQ +LKY QLFN+ D+ +G +G QAR+I++QS LPQ LA IW L+D+D DGKL
Sbjct: 216 AVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLT 275
Query: 416 CEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
EEF+LAM+L + A G+P+P LPPE IPP
Sbjct: 276 AEEFILAMHLIDVAMSGQPLPPVLPPEYIPP 306
Score = 106 bits (254), Expect = 6e-22
Identities = 47/88 (53%), Positives = 61/88 (69%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGK 63
D W I E AK + F +L P++G +TG+QA+ F QS LP PVL QIW+LAD N DG+
Sbjct: 13 DIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGR 72
Query: 64 LDLKEFSIACKIINLKLRGLEVPKMLPP 91
+D EFSIA K+I LKL+G ++P LPP
Sbjct: 73 MDQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 71.3 bits (167), Expect = 2e-11
Identities = 36/87 (41%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 355 WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKL 414
W + ++ K+ Q F++ + +G +G QAR+ QS LPQ LAQIWALAD++ DG++
Sbjct: 15 WAITVEERAKHDQQFHSL-KPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRM 73
Query: 415 GCEEFVLAMYLCEKATQGEPVPARLPP 441
EF +AM L + QG +P+ LPP
Sbjct: 74 DQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 69.7 bits (163), Expect = 6e-11
Identities = 32/90 (35%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F + ++G+LTG QA+ ++QS LP L IW+L+D + DGKL
Sbjct: 215 WAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKL 274
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A +I++ + G +P +LPP I
Sbjct: 275 TAEEFILAMHLIDVAMSGQPLPPVLPPEYI 304
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/90 (31%), Positives = 52/90 (57%)
Query: 633 QCQLEWEKKRTRELEALRSEEQSKVLSLKAKCQSLSAQLGAESVRCSTLAASIRDTRTAV 692
Q QLEWE+ R +EL R++EQ ++ LKAK ++L +L A + + L ++D R +
Sbjct: 444 QRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRL 503
Query: 693 AADKRTIDGMRSDRDSSMAEMQQLKARVKE 722
++ I+ R+ +AE+ L+ +++E
Sbjct: 504 TTQRQEIESTNKSRELRIAEITHLQQQLQE 533
Score = 52.8 bits (121), Expect = 8e-06
Identities = 24/54 (44%), Positives = 36/54 (66%), Gaps = 3/54 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQ--DPAWWQGELRGMVGLFPSNYVTKL 1302
ALYP+ +++ DE++ + DI+ V D SQ +P W GEL+G G FP+NY K+
Sbjct: 747 ALYPFESRSHDEITIQPGDIVMV-DESQTGEPGWLGGELKGKTGWFPANYAEKI 799
Score = 49.2 bits (112), Expect = 1e-04
Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 6/81 (7%)
Query: 887 WRCVYPFVGRSADELSVQPGDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESYVE-----D 941
+R +YPF RS DE+++QPGD IV +G++GWFP +Y E +
Sbjct: 745 YRALYPFESRSHDEITIQPGD-IVMVDESQTGEPGWLGGELKGKTGWFPANYAEKIPENE 803
Query: 942 LNAPTAFVTEVIETLEPKTQL 962
+ AP VT+ PK L
Sbjct: 804 VPAPVKPVTDSTSAPAPKLAL 824
Score = 35.5 bits (78), Expect = 1.3
Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 8/83 (9%)
Query: 980 ALPAVVDPGRTVSE---PVSVEDDGE--FYIASYPYSSSEPGDLVFEAGERIEVVR-RDG 1033
A PAV P T + +S +++ + +Y A YP+ S ++ + G+ + V + G
Sbjct: 716 AKPAVQAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMVDESQTG 775
Query: 1034 D--WWTGRIGARTGIFPSNYVSR 1054
+ W G + +TG FP+NY +
Sbjct: 776 EPGWLGGELKGKTGWFPANYAEK 798
Score = 35.1 bits (77), Expect = 1.7
Identities = 17/57 (29%), Positives = 33/57 (57%), Gaps = 7/57 (12%)
Query: 1163 QALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKGRNRQVGWFPASYVK 1217
+AL + + S +++++ G +++V + + GW GEL+ K GWFPA+Y +
Sbjct: 746 RALYPFESRSHDEITIQPGDIVMVDESQTGEPGWLGGELKGK-----TGWFPANYAE 797
Score = 33.9 bits (74), Expect = 3.8
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 466 RRENMARGQAELERRRTQLADAQMKEKVRGRGLNQSQ 502
+REN RG ELE+RR L + Q KE+ R L +++
Sbjct: 354 KRENFERGNLELEKRRQALLEQQRKEQERLAQLERAE 390
>DQ340865-1|ABC69037.1| 1076|Homo sapiens intersectin 1 short form
protein.
Length = 1076
Score = 134 bits (323), Expect = 3e-30
Identities = 82/211 (38%), Positives = 110/211 (52%), Gaps = 10/211 (4%)
Query: 242 PIMSSQPLI--SASTISAQPLGTMQPLIGTAPPIMGATQALIQSPPLSGPQQPAPVTAAS 299
P+M QP+ SA + +M PL AP MG+ + SP L A V +
Sbjct: 98 PVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLA 157
Query: 300 FGGXXXXXXXXXXXXGQPVTSTPIAALNKEVISKPGSVVTSP---EVPMGVMSPPPM-EW 355
G P + P ++ S PGS + + V S PP+ EW
Sbjct: 158 NGAPPVIQPLPAFA--HPAATLPKSSSFSR--SGPGSQLNTKLQKAQSFDVASVPPVAEW 213
Query: 356 GVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLG 415
VPQ +LKY QLFN+ D+ +G +G QAR+I++QS LPQ LA IW L+D+D DGKL
Sbjct: 214 AVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLT 273
Query: 416 CEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
EEF+LAM+L + A G+P+P LPPE IPP
Sbjct: 274 AEEFILAMHLIDVAMSGQPLPPVLPPEYIPP 304
Score = 106 bits (254), Expect = 6e-22
Identities = 47/88 (53%), Positives = 61/88 (69%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGK 63
D W I E AK + F +L P++G +TG+QA+ F QS LP PVL QIW+LAD N DG+
Sbjct: 11 DIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGR 70
Query: 64 LDLKEFSIACKIINLKLRGLEVPKMLPP 91
+D EFSIA K+I LKL+G ++P LPP
Sbjct: 71 MDQVEFSIAMKLIKLKLQGYQLPSALPP 98
Score = 94.7 bits (225), Expect = 2e-18
Identities = 92/348 (26%), Positives = 146/348 (41%), Gaps = 41/348 (11%)
Query: 980 ALPAVVDPGRTVSE---PVSVEDDGE--FYIASYPYSSSEPGDLVFEAGERIEVVR-RDG 1033
A PAV P T + +S +++ + +Y A YP+ S ++ + G+ + V + G
Sbjct: 714 AKPAVQAPWSTAEKGPLTISAQENVKVVYYRALYPFESRSHDEITIQPGDIVMVDESQTG 773
Query: 1034 D--WWTGRIGARTGIFPSNYVSR---EAAPAATSXXXXXXXXXXXXXXXXXX---XXXXT 1085
+ W G + +TG FP+NY + PA +
Sbjct: 774 EPGWLGGELKGKTGWFPANYAEKIPENEVPAPVKPVTDSTSAPAPKLALRETPAPLAVTS 833
Query: 1086 SPPNTTPPIPAS-QLIW--TSNELAYTSVTFLLAQDQKSSTPISSEVAMITDXXXXXXXX 1142
S P+TTP A W ++NE T A + P + ++
Sbjct: 834 SEPSTTPNNWADFSSTWPTSTNEKPETDNWDAWAAQPSLTVPSAGQLRQ-----RSAFTP 888
Query: 1143 XXXXDSGRDSVTGR-RKHEIVQALASYT--ATSPEQLSLMKGQLLVVRKKADSGWWEGEL 1199
S V G+ K E +QA A Y A L+ K ++ V ++ D WW GE+
Sbjct: 889 ATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDM-WWFGEV 947
Query: 1200 QAKGRNRQVGWFPASYVKVL-----QSSGRTSGRTTPVLSSKMDALPTETVI---DKVVA 1251
Q Q GWFP SYVK++ +S+ SG + S K A P + ++ +A
Sbjct: 948 QG-----QKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKPVVSGEEFIA 1002
Query: 1252 LYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+Y Y + +L+F++ D+I VT + D WW G + G+FPSNYV
Sbjct: 1003 MYTYESSEQGDLTFQQGDVILVTKKDGD--WWTGTVGDKAGVFPSNYV 1048
Score = 85.0 bits (201), Expect = 2e-15
Identities = 48/125 (38%), Positives = 69/125 (55%), Gaps = 24/125 (19%)
Query: 928 RGQSGWFPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDP 987
+GQ GWFP+SYV+ ++ P + T ++ +S+ +L V P
Sbjct: 948 QGQKGWFPKSYVKLISGP----------IRKSTSMDS--------GSSESPASLKRVASP 989
Query: 988 GRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIF 1047
++PV GE +IA Y Y SSE GDL F+ G+ I V ++DGDWWTG +G + G+F
Sbjct: 990 A---AKPVV---SGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTVGDKAGVF 1043
Query: 1048 PSNYV 1052
PSNYV
Sbjct: 1044 PSNYV 1048
Score = 71.3 bits (167), Expect = 2e-11
Identities = 36/87 (41%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 355 WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKL 414
W + ++ K+ Q F++ + +G +G QAR+ QS LPQ LAQIWALAD++ DG++
Sbjct: 13 WAITVEERAKHDQQFHSL-KPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRM 71
Query: 415 GCEEFVLAMYLCEKATQGEPVPARLPP 441
EF +AM L + QG +P+ LPP
Sbjct: 72 DQVEFSIAMKLIKLKLQGYQLPSALPP 98
Score = 69.7 bits (163), Expect = 6e-11
Identities = 32/90 (35%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F + ++G+LTG QA+ ++QS LP L IW+L+D + DGKL
Sbjct: 213 WAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKL 272
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A +I++ + G +P +LPP I
Sbjct: 273 TAEEFILAMHLIDVAMSGQPLPPVLPPEYI 302
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/90 (31%), Positives = 52/90 (57%)
Query: 633 QCQLEWEKKRTRELEALRSEEQSKVLSLKAKCQSLSAQLGAESVRCSTLAASIRDTRTAV 692
Q QLEWE+ R +EL R++EQ ++ LKAK ++L +L A + + L ++D R +
Sbjct: 442 QRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRL 501
Query: 693 AADKRTIDGMRSDRDSSMAEMQQLKARVKE 722
++ I+ R+ +AE+ L+ +++E
Sbjct: 502 TTQRQEIESTNKSRELRIAEITHLQQQLQE 531
Score = 52.8 bits (121), Expect = 8e-06
Identities = 24/54 (44%), Positives = 36/54 (66%), Gaps = 3/54 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQ--DPAWWQGELRGMVGLFPSNYVTKL 1302
ALYP+ +++ DE++ + DI+ V D SQ +P W GEL+G G FP+NY K+
Sbjct: 745 ALYPFESRSHDEITIQPGDIVMV-DESQTGEPGWLGGELKGKTGWFPANYAEKI 797
Score = 52.0 bits (119), Expect = 1e-05
Identities = 24/54 (44%), Positives = 36/54 (66%), Gaps = 3/54 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
ALYP+ A+ + L+F K+D+I V + Q WW GE++G G FP +YV KL++
Sbjct: 913 ALYPWRAKKDNHLNFNKNDVITVLE--QQDMWWFGEVQGQKGWFPKSYV-KLIS 963
Score = 49.2 bits (112), Expect = 1e-04
Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 6/81 (7%)
Query: 887 WRCVYPFVGRSADELSVQPGDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESYVE-----D 941
+R +YPF RS DE+++QPGD IV +G++GWFP +Y E +
Sbjct: 743 YRALYPFESRSHDEITIQPGD-IVMVDESQTGEPGWLGGELKGKTGWFPANYAEKIPENE 801
Query: 942 LNAPTAFVTEVIETLEPKTQL 962
+ AP VT+ PK L
Sbjct: 802 VPAPVKPVTDSTSAPAPKLAL 822
Score = 41.5 bits (93), Expect = 0.019
Identities = 26/68 (38%), Positives = 39/68 (57%), Gaps = 9/68 (13%)
Query: 1165 LASYTATSPEQ--LSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSS 1222
+A YT S EQ L+ +G +++V KK D WW G + K G FP++YV++ S
Sbjct: 1001 IAMYTYESSEQGDLTFQQGDVILVTKK-DGDWWTGTVGDKA-----GVFPSNYVRLKDSE 1054
Query: 1223 GR-TSGRT 1229
G T+G+T
Sbjct: 1055 GSGTAGKT 1062
Score = 33.9 bits (74), Expect = 3.8
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 466 RRENMARGQAELERRRTQLADAQMKEKVRGRGLNQSQ 502
+REN RG ELE+RR L + Q KE+ R L +++
Sbjct: 352 KRENFERGNLELEKRRQALLEQQRKEQERLAQLERAE 388
>BC073744-1|AAH73744.1| 648|Homo sapiens ITSN1 protein protein.
Length = 648
Score = 134 bits (323), Expect = 3e-30
Identities = 82/211 (38%), Positives = 110/211 (52%), Gaps = 10/211 (4%)
Query: 242 PIMSSQPLI--SASTISAQPLGTMQPLIGTAPPIMGATQALIQSPPLSGPQQPAPVTAAS 299
P+M QP+ SA + +M PL AP MG+ + SP L A V +
Sbjct: 100 PVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLA 159
Query: 300 FGGXXXXXXXXXXXXGQPVTSTPIAALNKEVISKPGSVVTSP---EVPMGVMSPPPM-EW 355
G P + P ++ S PGS + + V S PP+ EW
Sbjct: 160 NGAPPVIQPLPAFA--HPAATLPKSSSFSR--SGPGSQLNTKLQKAQSFDVASVPPVAEW 215
Query: 356 GVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLG 415
VPQ +LKY QLFN+ D+ +G +G QAR+I++QS LPQ LA IW L+D+D DGKL
Sbjct: 216 AVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLT 275
Query: 416 CEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
EEF+LAM+L + A G+P+P LPPE IPP
Sbjct: 276 AEEFILAMHLIDVAMSGQPLPPVLPPEYIPP 306
Score = 106 bits (254), Expect = 6e-22
Identities = 47/88 (53%), Positives = 61/88 (69%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGK 63
D W I E AK + F +L P++G +TG+QA+ F QS LP PVL QIW+LAD N DG+
Sbjct: 13 DIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGR 72
Query: 64 LDLKEFSIACKIINLKLRGLEVPKMLPP 91
+D EFSIA K+I LKL+G ++P LPP
Sbjct: 73 MDQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 71.3 bits (167), Expect = 2e-11
Identities = 36/87 (41%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 355 WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKL 414
W + ++ K+ Q F++ + +G +G QAR+ QS LPQ LAQIWALAD++ DG++
Sbjct: 15 WAITVEERAKHDQQFHSL-KPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRM 73
Query: 415 GCEEFVLAMYLCEKATQGEPVPARLPP 441
EF +AM L + QG +P+ LPP
Sbjct: 74 DQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 69.7 bits (163), Expect = 6e-11
Identities = 32/90 (35%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F + ++G+LTG QA+ ++QS LP L IW+L+D + DGKL
Sbjct: 215 WAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKL 274
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A +I++ + G +P +LPP I
Sbjct: 275 TAEEFILAMHLIDVAMSGQPLPPVLPPEYI 304
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/90 (31%), Positives = 52/90 (57%)
Query: 633 QCQLEWEKKRTRELEALRSEEQSKVLSLKAKCQSLSAQLGAESVRCSTLAASIRDTRTAV 692
Q QLEWE+ R +EL R++EQ ++ LKAK ++L +L A + + L ++D R +
Sbjct: 444 QRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRL 503
Query: 693 AADKRTIDGMRSDRDSSMAEMQQLKARVKE 722
++ I+ R+ +AE+ L+ +++E
Sbjct: 504 TTQRQEIESTNKSRELRIAEITHLQQQLQE 533
Score = 33.9 bits (74), Expect = 3.8
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 466 RRENMARGQAELERRRTQLADAQMKEKVRGRGLNQSQ 502
+REN RG ELE+RR L + Q KE+ R L +++
Sbjct: 354 KRENFERGNLELEKRRQALLEQQRKEQERLAQLERAE 390
>BC058925-1|AAH58925.1| 634|Homo sapiens ITSN1 protein protein.
Length = 634
Score = 134 bits (323), Expect = 3e-30
Identities = 82/211 (38%), Positives = 110/211 (52%), Gaps = 10/211 (4%)
Query: 242 PIMSSQPLI--SASTISAQPLGTMQPLIGTAPPIMGATQALIQSPPLSGPQQPAPVTAAS 299
P+M QP+ SA + +M PL AP MG+ + SP L A V +
Sbjct: 100 PVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLA 159
Query: 300 FGGXXXXXXXXXXXXGQPVTSTPIAALNKEVISKPGSVVTSP---EVPMGVMSPPPM-EW 355
G P + P ++ S PGS + + V S PP+ EW
Sbjct: 160 NGAPPVIQPLPAFA--HPAATLPKSSSFSR--SGPGSQLNTKLQKAQSFDVASVPPVAEW 215
Query: 356 GVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLG 415
VPQ +LKY QLFN+ D+ +G +G QAR+I++QS LPQ LA IW L+D+D DGKL
Sbjct: 216 AVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLT 275
Query: 416 CEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
EEF+LAM+L + A G+P+P LPPE IPP
Sbjct: 276 AEEFILAMHLIDVAMSGQPLPPVLPPEYIPP 306
Score = 106 bits (254), Expect = 6e-22
Identities = 47/88 (53%), Positives = 61/88 (69%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGK 63
D W I E AK + F +L P++G +TG+QA+ F QS LP PVL QIW+LAD N DG+
Sbjct: 13 DIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGR 72
Query: 64 LDLKEFSIACKIINLKLRGLEVPKMLPP 91
+D EFSIA K+I LKL+G ++P LPP
Sbjct: 73 MDQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 71.3 bits (167), Expect = 2e-11
Identities = 36/87 (41%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 355 WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKL 414
W + ++ K+ Q F++ + +G +G QAR+ QS LPQ LAQIWALAD++ DG++
Sbjct: 15 WAITVEERAKHDQQFHSL-KPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRM 73
Query: 415 GCEEFVLAMYLCEKATQGEPVPARLPP 441
EF +AM L + QG +P+ LPP
Sbjct: 74 DQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 69.7 bits (163), Expect = 6e-11
Identities = 32/90 (35%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F + ++G+LTG QA+ ++QS LP L IW+L+D + DGKL
Sbjct: 215 WAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKL 274
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A +I++ + G +P +LPP I
Sbjct: 275 TAEEFILAMHLIDVAMSGQPLPPVLPPEYI 304
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/90 (31%), Positives = 52/90 (57%)
Query: 633 QCQLEWEKKRTRELEALRSEEQSKVLSLKAKCQSLSAQLGAESVRCSTLAASIRDTRTAV 692
Q QLEWE+ R +EL R++EQ ++ LKAK ++L +L A + + L ++D R +
Sbjct: 444 QRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRL 503
Query: 693 AADKRTIDGMRSDRDSSMAEMQQLKARVKE 722
++ I+ R+ +AE+ L+ +++E
Sbjct: 504 TTQRQEIESTNKSRELRIAEITHLQQQLQE 533
Score = 33.9 bits (74), Expect = 3.8
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 466 RRENMARGQAELERRRTQLADAQMKEKVRGRGLNQSQ 502
+REN RG ELE+RR L + Q KE+ R L +++
Sbjct: 354 KRENFERGNLELEKRRQALLEQQRKEQERLAQLERAE 390
>BC039036-1|AAH39036.1| 345|Homo sapiens Similar to intersectin 1
(SH3 domain protein) protein.
Length = 345
Score = 134 bits (323), Expect = 3e-30
Identities = 82/211 (38%), Positives = 110/211 (52%), Gaps = 10/211 (4%)
Query: 242 PIMSSQPLI--SASTISAQPLGTMQPLIGTAPPIMGATQALIQSPPLSGPQQPAPVTAAS 299
P+M QP+ SA + +M PL AP MG+ + SP L A V +
Sbjct: 100 PVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVPMGSIPVVGMSPTLVSSVPTAAVPPLA 159
Query: 300 FGGXXXXXXXXXXXXGQPVTSTPIAALNKEVISKPGSVVTSP---EVPMGVMSPPPM-EW 355
G P + P ++ S PGS + + V S PP+ EW
Sbjct: 160 NGAPPVIQPLPAFA--HPAATLPKSSSFSR--SGPGSQLNTKLQKAQSFDVASVPPVAEW 215
Query: 356 GVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLG 415
VPQ +LKY QLFN+ D+ +G +G QAR+I++QS LPQ LA IW L+D+D DGKL
Sbjct: 216 AVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLT 275
Query: 416 CEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
EEF+LAM+L + A G+P+P LPPE IPP
Sbjct: 276 AEEFILAMHLIDVAMSGQPLPPVLPPEYIPP 306
Score = 106 bits (254), Expect = 6e-22
Identities = 47/88 (53%), Positives = 61/88 (69%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGK 63
D W I E AK + F +L P++G +TG+QA+ F QS LP PVL QIW+LAD N DG+
Sbjct: 13 DIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGR 72
Query: 64 LDLKEFSIACKIINLKLRGLEVPKMLPP 91
+D EFSIA K+I LKL+G ++P LPP
Sbjct: 73 MDQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 71.3 bits (167), Expect = 2e-11
Identities = 36/87 (41%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 355 WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKL 414
W + ++ K+ Q F++ + +G +G QAR+ QS LPQ LAQIWALAD++ DG++
Sbjct: 15 WAITVEERAKHDQQFHSL-KPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRM 73
Query: 415 GCEEFVLAMYLCEKATQGEPVPARLPP 441
EF +AM L + QG +P+ LPP
Sbjct: 74 DQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 69.7 bits (163), Expect = 6e-11
Identities = 32/90 (35%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F + ++G+LTG QA+ ++QS LP L IW+L+D + DGKL
Sbjct: 215 WAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKL 274
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A +I++ + G +P +LPP I
Sbjct: 275 TAEEFILAMHLIDVAMSGQPLPPVLPPEYI 304
>BC038963-1|AAH38963.1| 611|Homo sapiens Similar to intersectin 2
protein.
Length = 611
Score = 132 bits (320), Expect = 6e-30
Identities = 109/350 (31%), Positives = 152/350 (43%), Gaps = 45/350 (12%)
Query: 183 PPMAPTVQPLIGTVQPLIGPDPLMGSVQPLIGSQPLAGPTPLVSSPQTLVNSSPLVSSQP 242
P + P + PLI MGS+ L QPL P+ S L +++ + P
Sbjct: 95 PVVLPPIMKQPPMFSPLISARFGMGSMPNLSIPQPLPPAAPITS----LSSATSGTNLPP 150
Query: 243 IMSSQPLISASTISAQPLGT---MQPLIGTAPPIMGATQALIQSPPLSGPQQPAPVTAAS 299
+M PL+ + + S+ P GT +QPL PI ++ L S +
Sbjct: 151 LMMPTPLVPSVSTSSLPNGTASLIQPL-----PIPYSSSTLPHGSSYS-------LMMGG 198
Query: 300 FGGXXXXXXXXXXXXGQPVT-----STPIAALNKEVISKP-GSVVTSPEVPMGVMSPPP- 352
FGG G + S A ++ +S P + TS + SP
Sbjct: 199 FGGASIQKAQSLIDLGSSRSWSSGSSAHSPATHRAPLSSPVPNSSTSSTASLSGNSPKTG 258
Query: 353 -MEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDAD 411
EW VPQP +LKY Q FN D++ +G SG QAR+ +LQS L Q LA IW LAD+D D
Sbjct: 259 TSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADIDGD 318
Query: 412 GKLGCEEFVLAMYLCEKATQGEPVPARLPPELIPPXXXXXXXXXXXXXX----------- 460
G+L EEF+LAM+L + A G+P+P LPPEL+PP
Sbjct: 319 GQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVPPSFRGGKQIDSINGTLPSYQKMQEEE 378
Query: 461 -------XXXXXRRENMARGQAELERRRTQLADAQMKEKVRGRGLNQSQW 503
R+ N RG ELE+RR L + Q +E R + +W
Sbjct: 379 PQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEW 428
Score = 103 bits (248), Expect = 3e-21
Identities = 46/86 (53%), Positives = 60/86 (69%)
Query: 6 WTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLD 65
W I + E K F NL P G +TG+QA+ F LQS LP PVL +IW+L+D N DGK+D
Sbjct: 15 WAITSEERTKHDRQFDNLKPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMD 74
Query: 66 LKEFSIACKIINLKLRGLEVPKMLPP 91
+EFSIA K+I LKL+G ++P +LPP
Sbjct: 75 QQEFSIAMKLIKLKLQGQQLPVVLPP 100
Score = 62.5 bits (145), Expect = 1e-08
Identities = 31/90 (34%), Positives = 49/90 (54%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F L ++G L+G QA+ +LQS L L IW+LAD + DG+L
Sbjct: 262 WAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADIDGDGQL 321
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A + ++ G +P LPP L+
Sbjct: 322 KAEEFILAMHLTDMAKAGQPLPLTLPPELV 351
>BC020921-1|AAH20921.1| 560|Homo sapiens ITSN2 protein protein.
Length = 560
Score = 129 bits (311), Expect = 7e-29
Identities = 120/395 (30%), Positives = 168/395 (42%), Gaps = 49/395 (12%)
Query: 134 QPSNQSLLGDFGSGQPLIQPLVQPVKPPVSTVPDLISGVKPLSQSLLDSPPMAPTVQPLI 193
+PS + GD L L PV + + DL K Q S M L
Sbjct: 33 KPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEF--SIAMKLIKLKLQ 90
Query: 194 GTVQPLIGPDPLMGS---VQPLIGSQPLAGPTPLVSSPQTLVNSSPLVSSQPIMSSQPLI 250
G P++ P P+M PLI ++ G P +S PQ L ++P+ S +SS
Sbjct: 91 GQQLPVVLP-PIMKQPPMFSPLISARFGMGSMPNLSIPQPLPPAAPITS----LSS---- 141
Query: 251 SASTISAQPLGTMQPLIGTAPP--IMGATQALIQSPPLSGPQQPAPVTAASFGGXXXXXX 308
+ S + PL PL+ + + T +LIQ PL P P ++++
Sbjct: 142 ATSGTNLPPLMMPTPLVPSVSTSSLPNGTASLIQ--PL-----PIPYSSSTLPHGSSYSL 194
Query: 309 XXXXXXGQPVTSTPIAALNKEVISKPGSVVTSPEVPMGVMSPPP--MEWGVPQPQKLKYT 366
G + + +I S TS + SP EW VPQP +LKY
Sbjct: 195 MMGGFGGASIQKA------QSLIDLGSSSSTSSTASLSGNSPKTGTSEWAVPQPTRLKYR 248
Query: 367 QLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLGCEEFVLAMYLC 426
Q FN D++ +G SG QAR+ +LQS L Q LA IW LAD+D DG+L EEF+LAM+L
Sbjct: 249 QKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADIDGDGQLKAEEFILAMHLT 308
Query: 427 EKATQGEPVPARLPPELIPPXXXXXXXXXXXXXX------------------XXXXXRRE 468
+ A G+P+P LPPEL+PP R+
Sbjct: 309 DMAKAGQPLPLTLPPELVPPSFRGGKQIDSINGTLPSYQKMQEEEPQKKLPVTFEDKRKA 368
Query: 469 NMARGQAELERRRTQLADAQMKEKVRGRGLNQSQW 503
N RG ELE+RR L + Q +E R + +W
Sbjct: 369 NYERGNMELEKRRQALMEQQQREAERKAQKEKEEW 403
Score = 103 bits (248), Expect = 3e-21
Identities = 46/86 (53%), Positives = 60/86 (69%)
Query: 6 WTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLD 65
W I + E K F NL P G +TG+QA+ F LQS LP PVL +IW+L+D N DGK+D
Sbjct: 15 WAITSEERTKHDRQFDNLKPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMD 74
Query: 66 LKEFSIACKIINLKLRGLEVPKMLPP 91
+EFSIA K+I LKL+G ++P +LPP
Sbjct: 75 QQEFSIAMKLIKLKLQGQQLPVVLPP 100
Score = 62.5 bits (145), Expect = 1e-08
Identities = 31/90 (34%), Positives = 49/90 (54%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F L ++G L+G QA+ +LQS L L IW+LAD + DG+L
Sbjct: 237 WAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADIDGDGQL 296
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A + ++ G +P LPP L+
Sbjct: 297 KAEEFILAMHLTDMAKAGQPLPLTLPPELV 326
>BX538175-1|CAD98050.1| 627|Homo sapiens hypothetical protein
protein.
Length = 627
Score = 123 bits (297), Expect = 4e-27
Identities = 55/97 (56%), Positives = 70/97 (72%)
Query: 350 PPPMEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLD 409
PP EW VPQ +LKY QLFN+ D+ +G +G QAR+I++QS LPQ LA IW L+D+D
Sbjct: 65 PPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDID 124
Query: 410 ADGKLGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
DGKL EEF+LAM+L + A G+P+P LPPE IPP
Sbjct: 125 QDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPP 161
Score = 69.7 bits (163), Expect = 6e-11
Identities = 32/90 (35%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + K+ + F + ++G+LTG QA+ ++QS LP L IW+L+D + DGKL
Sbjct: 70 WAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKL 129
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF +A +I++ + G +P +LPP I
Sbjct: 130 TAEEFILAMHLIDVAMSGQPLPPVLPPEYI 159
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/90 (31%), Positives = 52/90 (57%)
Query: 633 QCQLEWEKKRTRELEALRSEEQSKVLSLKAKCQSLSAQLGAESVRCSTLAASIRDTRTAV 692
Q QLEWE+ R +EL R++EQ ++ LKAK ++L +L A + + L ++D R +
Sbjct: 299 QRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRL 358
Query: 693 AADKRTIDGMRSDRDSSMAEMQQLKARVKE 722
++ I+ R+ +AE+ L+ +++E
Sbjct: 359 TTQRQEIESTNKSRELRIAEITHLQQQLQE 388
Score = 36.3 bits (80), Expect = 0.72
Identities = 12/24 (50%), Positives = 20/24 (83%)
Query: 887 WRCVYPFVGRSADELSVQPGDLIV 910
+R +YPF RS DE+++QPGD+++
Sbjct: 600 YRALYPFESRSHDEITIQPGDIVM 623
Score = 33.9 bits (74), Expect = 3.8
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 466 RRENMARGQAELERRRTQLADAQMKEKVRGRGLNQSQ 502
+REN RG ELE+RR L + Q KE+ R L +++
Sbjct: 209 KRENFERGNLELEKRRQALLEQQRKEQERLAQLERAE 245
>X17576-1|CAA35599.1| 377|Homo sapiens protein ( Human melanoma mRNA
for nck protein, showing homology to src. ).
Length = 377
Score = 108 bits (259), Expect = 1e-22
Identities = 57/142 (40%), Positives = 86/142 (60%), Gaps = 9/142 (6%)
Query: 1167 SYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSS--GR 1224
+Y A ++LSL+KG ++V +K GWW G N QVGWFP++YV S G
Sbjct: 116 NYMAEREDELSLIKGTKVIVMEKCSDGWWRGSY-----NGQVGWFPSNYVTEEGDSPLGD 170
Query: 1225 TSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQ-DPAWW 1283
G + L++ ++ L T V+ V ALYP+++ N +EL+FEK D++ V ++ + DP WW
Sbjct: 171 HVGSLSEKLAAVVNNLNTGQVLHVVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWW 230
Query: 1284 Q-GELRGMVGLFPSNYVTKLVN 1304
+ ++ GMVGL P NYVT + N
Sbjct: 231 KCRKINGMVGLVPKNYVTVMQN 252
Score = 44.0 bits (99), Expect = 0.004
Identities = 27/76 (35%), Positives = 45/76 (59%), Gaps = 7/76 (9%)
Query: 1154 TGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKA--DSGWWEGELQAKGRNRQVGWF 1211
TG+ H +VQAL +++++ E+L+ KG ++ V +K D WW + + N VG
Sbjct: 188 TGQVLH-VVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWW----KCRKINGMVGLV 242
Query: 1212 PASYVKVLQSSGRTSG 1227
P +YV V+Q++ TSG
Sbjct: 243 PKNYVTVMQNNPLTSG 258
Score = 43.2 bits (97), Expect = 0.006
Identities = 34/128 (26%), Positives = 60/128 (46%), Gaps = 13/128 (10%)
Query: 930 QSGWFPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGG-ALPAVVDPG 988
++G+ P +YVE N+ A +++ L+ GI +V + + D A + VDPG
Sbjct: 47 KTGFVPSNYVERKNS--ARKASIVKNLKDTL---GIGKVKRKPSVPDSASPADDSFVDPG 101
Query: 989 RTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIF 1047
+ + + Y+ + Y + +L G ++ V+ + D WW G + G F
Sbjct: 102 ERLYDL-----NMPAYV-KFNYMAEREDELSLIKGTKVIVMEKCSDGWWRGSYNGQVGWF 155
Query: 1048 PSNYVSRE 1055
PSNYV+ E
Sbjct: 156 PSNYVTEE 163
Score = 42.7 bits (96), Expect = 0.008
Identities = 21/52 (40%), Positives = 31/52 (59%), Gaps = 4/52 (7%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRR---DGDWWTGR-IGARTGIFPSNYVS 1053
A YP+SSS +L FE G+ ++V+ + D +WW R I G+ P NYV+
Sbjct: 197 ALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVPKNYVT 248
Score = 35.5 bits (78), Expect = 1.3
Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 3/54 (5%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQ-GELRGMVGLFPSNYVTK 1301
VVA + Y AQ EL +K++ + + D S+ +WW+ G PSNYV +
Sbjct: 7 VVAKFDYVAQQEQELDIKKNERLWLLDDSK--SWWRVRNSMNKTGFVPSNYVER 58
Score = 34.7 bits (76), Expect = 2.2
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGA-RTGIFPSNYVSRE 1055
+A + Y + + +L + ER+ ++ WW R +TG PSNYV R+
Sbjct: 8 VAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERK 59
>BC006403-1|AAH06403.1| 377|Homo sapiens NCK adaptor protein 1
protein.
Length = 377
Score = 108 bits (259), Expect = 1e-22
Identities = 57/142 (40%), Positives = 86/142 (60%), Gaps = 9/142 (6%)
Query: 1167 SYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSS--GR 1224
+Y A ++LSL+KG ++V +K GWW G N QVGWFP++YV S G
Sbjct: 116 NYMAEREDELSLIKGTKVIVMEKCSDGWWRGSY-----NGQVGWFPSNYVTEEGDSPLGD 170
Query: 1225 TSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQ-DPAWW 1283
G + L++ ++ L T V+ V ALYP+++ N +EL+FEK D++ V ++ + DP WW
Sbjct: 171 HVGSLSEKLAAVVNNLNTGQVLHVVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWW 230
Query: 1284 Q-GELRGMVGLFPSNYVTKLVN 1304
+ ++ GMVGL P NYVT + N
Sbjct: 231 KCRKINGMVGLVPKNYVTVMQN 252
Score = 44.0 bits (99), Expect = 0.004
Identities = 27/76 (35%), Positives = 45/76 (59%), Gaps = 7/76 (9%)
Query: 1154 TGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKA--DSGWWEGELQAKGRNRQVGWF 1211
TG+ H +VQAL +++++ E+L+ KG ++ V +K D WW + + N VG
Sbjct: 188 TGQVLH-VVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWW----KCRKINGMVGLV 242
Query: 1212 PASYVKVLQSSGRTSG 1227
P +YV V+Q++ TSG
Sbjct: 243 PKNYVTVMQNNPLTSG 258
Score = 43.2 bits (97), Expect = 0.006
Identities = 34/128 (26%), Positives = 60/128 (46%), Gaps = 13/128 (10%)
Query: 930 QSGWFPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGG-ALPAVVDPG 988
++G+ P +YVE N+ A +++ L+ GI +V + + D A + VDPG
Sbjct: 47 KTGFVPSNYVERKNS--ARKASIVKNLKDTL---GIGKVKRKPSVPDSASPADDSFVDPG 101
Query: 989 RTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIF 1047
+ + + Y+ + Y + +L G ++ V+ + D WW G + G F
Sbjct: 102 ERLYDL-----NMPAYV-KFNYMAEREDELSLIKGTKVIVMEKCSDGWWRGSYNGQVGWF 155
Query: 1048 PSNYVSRE 1055
PSNYV+ E
Sbjct: 156 PSNYVTEE 163
Score = 42.7 bits (96), Expect = 0.008
Identities = 21/52 (40%), Positives = 31/52 (59%), Gaps = 4/52 (7%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRR---DGDWWTGR-IGARTGIFPSNYVS 1053
A YP+SSS +L FE G+ ++V+ + D +WW R I G+ P NYV+
Sbjct: 197 ALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVPKNYVT 248
Score = 35.5 bits (78), Expect = 1.3
Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 3/54 (5%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQ-GELRGMVGLFPSNYVTK 1301
VVA + Y AQ EL +K++ + + D S+ +WW+ G PSNYV +
Sbjct: 7 VVAKFDYVAQQEQELDIKKNERLWLLDDSK--SWWRVRNSMNKTGFVPSNYVER 58
Score = 34.7 bits (76), Expect = 2.2
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGA-RTGIFPSNYVSRE 1055
+A + Y + + +L + ER+ ++ WW R +TG PSNYV R+
Sbjct: 8 VAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERK 59
>AK021545-1|BAB13841.1| 436|Homo sapiens protein ( Homo sapiens
cDNA FLJ11483 fis, clone HEMBA1001822, highly similar to
Mus musculus Ese2L protein mRNA. ).
Length = 436
Score = 91.9 bits (218), Expect = 1e-17
Identities = 54/145 (37%), Positives = 71/145 (48%), Gaps = 18/145 (12%)
Query: 377 TGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLGCEEFVLAMYLCEKATQGEPVP 436
+G SG QAR+ +LQS L Q LA IW LAD+D DG+L EEF+LAM+L + A G+P+P
Sbjct: 2 SGYLSGFQARNALLQSNLSQTQLATIWTLADIDGDGQLKAEEFILAMHLTDMAKAGQPLP 61
Query: 437 ARLPPELIPPXXXXXXXXXXXXXX------------------XXXXXRRENMARGQAELE 478
LPPEL+PP R+ N RG ELE
Sbjct: 62 LTLPPELVPPSFRGGKQIDSINGTLPSYQKMQEEEPQKKLPVTFEDKRKANYERGNMELE 121
Query: 479 RRRTQLADAQMKEKVRGRGLNQSQW 503
+RR L + Q +E R + +W
Sbjct: 122 KRRQALMEQQQREAERKAQKEKEEW 146
Score = 57.2 bits (132), Expect = 4e-07
Identities = 27/69 (39%), Positives = 42/69 (60%)
Query: 26 VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLDLKEFSIACKIINLKLRGLEV 85
++G L+G QA+ +LQS L L IW+LAD + DG+L +EF +A + ++ G +
Sbjct: 1 MSGYLSGFQARNALLQSNLSQTQLATIWTLADIDGDGQLKAEEFILAMHLTDMAKAGQPL 60
Query: 86 PKMLPPSLI 94
P LPP L+
Sbjct: 61 PLTLPPELV 69
>BC007195-1|AAH07195.1| 380|Homo sapiens NCK adaptor protein 2
protein.
Length = 380
Score = 89.4 bits (212), Expect = 7e-17
Identities = 50/142 (35%), Positives = 76/142 (53%), Gaps = 13/142 (9%)
Query: 1167 SYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTS 1226
+Y A ++LSL+KG + V +K GWW G N Q+GWFP++Y VL+ +
Sbjct: 121 AYVAEREDELSLVKGSRVTVMEKCSDGWWRGSY-----NGQIGWFPSNY--VLEEVDEAA 173
Query: 1227 GRTTPVLSSKMDALPT----ETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQ-DPA 1281
+ LS + A + V+ V LYP+++ +EL+FEK + + V ++ + DP
Sbjct: 174 AESPSFLSLRKGASLSNGQGSRVLHVVQTLYPFSSVTEEELNFEKGETMEVIEKPENDPE 233
Query: 1282 WWQ-GELRGMVGLFPSNYVTKL 1302
WW+ RG VGL P NYV L
Sbjct: 234 WWKCKNARGQVGLVPKNYVVVL 255
Score = 51.2 bits (117), Expect = 2e-05
Identities = 47/172 (27%), Positives = 77/172 (44%), Gaps = 35/172 (20%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
IV A YTA ++L + K + L + + + WW + + + G+ P++YV+
Sbjct: 6 IVIAKWDYTAQQDQELDIKKNERLWLLDDSKT-WW----RVRNAANRTGYVPSNYVERKN 60
Query: 1221 SSGRTS-----------GRTTPVLSSKMDALPTETV----------IDKVVAL------- 1252
S + S G+T S++ DA PT + D++ L
Sbjct: 61 SLKKGSLVKNLKDTLGLGKTRRKTSAR-DASPTPSTDAEYPANGSGADRIYDLNIPAFVK 119
Query: 1253 YPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
+ Y A+ DELS K + V ++ D WW+G G +G FPSNYV + V+
Sbjct: 120 FAYVAEREDELSLVKGSRVTVMEKCSD-GWWRGSYNGQIGWFPSNYVLEEVD 170
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 1008 YPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYVSREAAPAA 1060
+ Y + +L G R+ V+ + D WW G + G FPSNYV E AA
Sbjct: 120 FAYVAEREDELSLVKGSRVTVMEKCSDGWWRGSYNGQIGWFPSNYVLEEVDEAA 173
Score = 39.1 bits (87), Expect = 0.10
Identities = 32/134 (23%), Positives = 54/134 (40%), Gaps = 6/134 (4%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGA-RTGIFPSNYVSREAAPAATSX 1063
IA + Y++ + +L + ER+ ++ WW R A RTG PSNYV R+ + S
Sbjct: 8 IAKWDYTAQQDQELDIKKNERLWLLDDSKTWWRVRNAANRTGYVPSNYVERKNSLKKGSL 67
Query: 1064 XXXXXXXXXXXXXXXXXXXXXTSP-PNTTPPIPA----SQLIWTSNELAYTSVTFLLAQD 1118
SP P+T PA + I+ N A+ ++ ++
Sbjct: 68 VKNLKDTLGLGKTRRKTSARDASPTPSTDAEYPANGSGADRIYDLNIPAFVKFAYVAERE 127
Query: 1119 QKSSTPISSEVAMI 1132
+ S S V ++
Sbjct: 128 DELSLVKGSRVTVM 141
Score = 38.7 bits (86), Expect = 0.14
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 6/82 (7%)
Query: 1155 GRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKA--DSGWWEGELQAKGRNRQVGWFP 1212
G R +VQ L +++ + E+L+ KG+ + V +K D WW + K QVG P
Sbjct: 193 GSRVLHVVQTLYPFSSVTEEELNFEKGETMEVIEKPENDPEWW----KCKNARGQVGLVP 248
Query: 1213 ASYVKVLQSSGRTSGRTTPVLS 1234
+YV VL P +S
Sbjct: 249 KNYVVVLSDGPALHPAHAPQIS 270
Score = 38.7 bits (86), Expect = 0.14
Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 4/49 (8%)
Query: 1008 YPYSSSEPGDLVFEAGERIEVVRR---DGDWWTGR-IGARTGIFPSNYV 1052
YP+SS +L FE GE +EV+ + D +WW + + G+ P NYV
Sbjct: 204 YPFSSVTEEELNFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYV 252
Score = 37.5 bits (83), Expect = 0.31
Identities = 23/61 (37%), Positives = 33/61 (54%), Gaps = 5/61 (8%)
Query: 1242 TETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQ-GELRGMVGLFPSNYVT 1300
TE VI V+A + YTAQ EL +K++ + + D S+ WW+ G PSNYV
Sbjct: 2 TEEVI--VIAKWDYTAQQDQELDIKKNERLWLLDDSK--TWWRVRNAANRTGYVPSNYVE 57
Query: 1301 K 1301
+
Sbjct: 58 R 58
>BC000103-1|AAH00103.1| 380|Homo sapiens NCK adaptor protein 2
protein.
Length = 380
Score = 89.4 bits (212), Expect = 7e-17
Identities = 50/142 (35%), Positives = 76/142 (53%), Gaps = 13/142 (9%)
Query: 1167 SYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTS 1226
+Y A ++LSL+KG + V +K GWW G N Q+GWFP++Y VL+ +
Sbjct: 121 AYVAEREDELSLVKGSRVTVMEKCSDGWWRGSY-----NGQIGWFPSNY--VLEEVDEAA 173
Query: 1227 GRTTPVLSSKMDALPT----ETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQ-DPA 1281
+ LS + A + V+ V LYP+++ +EL+FEK + + V ++ + DP
Sbjct: 174 AESPSFLSLRKGASLSNGQGSRVLHVVQTLYPFSSVTEEELNFEKGETMEVIEKPENDPE 233
Query: 1282 WWQ-GELRGMVGLFPSNYVTKL 1302
WW+ RG VGL P NYV L
Sbjct: 234 WWKCKNARGQVGLVPKNYVVVL 255
Score = 51.2 bits (117), Expect = 2e-05
Identities = 47/172 (27%), Positives = 77/172 (44%), Gaps = 35/172 (20%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
IV A YTA ++L + K + L + + + WW + + + G+ P++YV+
Sbjct: 6 IVIAKWDYTAQQDQELDIKKNERLWLLDDSKT-WW----RVRNAANRTGYVPSNYVERKN 60
Query: 1221 SSGRTS-----------GRTTPVLSSKMDALPTETV----------IDKVVAL------- 1252
S + S G+T S++ DA PT + D++ L
Sbjct: 61 SLKKGSLVKNLKDTLGLGKTRRKTSAR-DASPTPSTDAEYPANGSGADRIYDLNIPAFVK 119
Query: 1253 YPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
+ Y A+ DELS K + V ++ D WW+G G +G FPSNYV + V+
Sbjct: 120 FAYVAEREDELSLVKGSRVTVMEKCSD-GWWRGSYNGQIGWFPSNYVLEEVD 170
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 1008 YPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYVSREAAPAA 1060
+ Y + +L G R+ V+ + D WW G + G FPSNYV E AA
Sbjct: 120 FAYVAEREDELSLVKGSRVTVMEKCSDGWWRGSYNGQIGWFPSNYVLEEVDEAA 173
Score = 39.1 bits (87), Expect = 0.10
Identities = 32/134 (23%), Positives = 54/134 (40%), Gaps = 6/134 (4%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGA-RTGIFPSNYVSREAAPAATSX 1063
IA + Y++ + +L + ER+ ++ WW R A RTG PSNYV R+ + S
Sbjct: 8 IAKWDYTAQQDQELDIKKNERLWLLDDSKTWWRVRNAANRTGYVPSNYVERKNSLKKGSL 67
Query: 1064 XXXXXXXXXXXXXXXXXXXXXTSP-PNTTPPIPA----SQLIWTSNELAYTSVTFLLAQD 1118
SP P+T PA + I+ N A+ ++ ++
Sbjct: 68 VKNLKDTLGLGKTRRKTSARDASPTPSTDAEYPANGSGADRIYDLNIPAFVKFAYVAERE 127
Query: 1119 QKSSTPISSEVAMI 1132
+ S S V ++
Sbjct: 128 DELSLVKGSRVTVM 141
Score = 38.7 bits (86), Expect = 0.14
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 6/82 (7%)
Query: 1155 GRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKA--DSGWWEGELQAKGRNRQVGWFP 1212
G R +VQ L +++ + E+L+ KG+ + V +K D WW + K QVG P
Sbjct: 193 GSRVLHVVQTLYPFSSVTEEELNFEKGETMEVIEKPENDPEWW----KCKNARGQVGLVP 248
Query: 1213 ASYVKVLQSSGRTSGRTTPVLS 1234
+YV VL P +S
Sbjct: 249 KNYVVVLSDGPALHPAHAPQIS 270
Score = 38.7 bits (86), Expect = 0.14
Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 4/49 (8%)
Query: 1008 YPYSSSEPGDLVFEAGERIEVVRR---DGDWWTGR-IGARTGIFPSNYV 1052
YP+SS +L FE GE +EV+ + D +WW + + G+ P NYV
Sbjct: 204 YPFSSVTEEELNFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYV 252
Score = 37.5 bits (83), Expect = 0.31
Identities = 23/61 (37%), Positives = 33/61 (54%), Gaps = 5/61 (8%)
Query: 1242 TETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQ-GELRGMVGLFPSNYVT 1300
TE VI V+A + YTAQ EL +K++ + + D S+ WW+ G PSNYV
Sbjct: 2 TEEVI--VIAKWDYTAQQDQELDIKKNERLWLLDDSK--TWWRVRNAANRTGYVPSNYVE 57
Query: 1301 K 1301
+
Sbjct: 58 R 58
>AF047487-1|AAC80284.1| 380|Homo sapiens Nck-2 protein.
Length = 380
Score = 89.4 bits (212), Expect = 7e-17
Identities = 50/142 (35%), Positives = 76/142 (53%), Gaps = 13/142 (9%)
Query: 1167 SYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTS 1226
+Y A ++LSL+KG + V +K GWW G N Q+GWFP++Y VL+ +
Sbjct: 121 AYVAEREDELSLVKGSRVTVMEKCSDGWWRGSY-----NGQIGWFPSNY--VLEEVDEAA 173
Query: 1227 GRTTPVLSSKMDALPT----ETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQ-DPA 1281
+ LS + A + V+ V LYP+++ +EL+FEK + + V ++ + DP
Sbjct: 174 AESPSFLSLRKGASLSNGQGSRVLHVVQTLYPFSSVTEEELNFEKGETMEVIEKPENDPE 233
Query: 1282 WWQ-GELRGMVGLFPSNYVTKL 1302
WW+ RG VGL P NYV L
Sbjct: 234 WWKCKNARGQVGLVPKNYVVVL 255
Score = 51.2 bits (117), Expect = 2e-05
Identities = 47/172 (27%), Positives = 77/172 (44%), Gaps = 35/172 (20%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
IV A YTA ++L + K + L + + + WW + + + G+ P++YV+
Sbjct: 6 IVIAKWDYTAQQDQELDIKKNERLWLLDDSKT-WW----RVRNAANRTGYVPSNYVERKN 60
Query: 1221 SSGRTS-----------GRTTPVLSSKMDALPTETV----------IDKVVAL------- 1252
S + S G+T S++ DA PT + D++ L
Sbjct: 61 SLKKGSLVKNLKDTLGLGKTRRKTSAR-DASPTPSTDAEYAANGSGADRIYDLNIPAFVK 119
Query: 1253 YPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
+ Y A+ DELS K + V ++ D WW+G G +G FPSNYV + V+
Sbjct: 120 FAYVAEREDELSLVKGSRVTVMEKCSD-GWWRGSYNGQIGWFPSNYVLEEVD 170
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 1008 YPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYVSREAAPAA 1060
+ Y + +L G R+ V+ + D WW G + G FPSNYV E AA
Sbjct: 120 FAYVAEREDELSLVKGSRVTVMEKCSDGWWRGSYNGQIGWFPSNYVLEEVDEAA 173
Score = 38.7 bits (86), Expect = 0.14
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 6/82 (7%)
Query: 1155 GRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKA--DSGWWEGELQAKGRNRQVGWFP 1212
G R +VQ L +++ + E+L+ KG+ + V +K D WW + K QVG P
Sbjct: 193 GSRVLHVVQTLYPFSSVTEEELNFEKGETMEVIEKPENDPEWW----KCKNARGQVGLVP 248
Query: 1213 ASYVKVLQSSGRTSGRTTPVLS 1234
+YV VL P +S
Sbjct: 249 KNYVVVLSDGPALHPAHAPQIS 270
Score = 38.7 bits (86), Expect = 0.14
Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 4/49 (8%)
Query: 1008 YPYSSSEPGDLVFEAGERIEVVRR---DGDWWTGR-IGARTGIFPSNYV 1052
YP+SS +L FE GE +EV+ + D +WW + + G+ P NYV
Sbjct: 204 YPFSSVTEEELNFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYV 252
Score = 38.3 bits (85), Expect = 0.18
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGA-RTGIFPSNYVSRE 1055
IA + Y++ + +L + ER+ ++ WW R A RTG PSNYV R+
Sbjct: 8 IAKWDYTAQQDQELDIKKNERLWLLDDSKTWWRVRNAANRTGYVPSNYVERK 59
Score = 37.5 bits (83), Expect = 0.31
Identities = 23/61 (37%), Positives = 33/61 (54%), Gaps = 5/61 (8%)
Query: 1242 TETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQ-GELRGMVGLFPSNYVT 1300
TE VI V+A + YTAQ EL +K++ + + D S+ WW+ G PSNYV
Sbjct: 2 TEEVI--VIAKWDYTAQQDQELDIKKNERLWLLDDSK--TWWRVRNAANRTGYVPSNYVE 57
Query: 1301 K 1301
+
Sbjct: 58 R 58
>AF043119-1|AAC04831.1| 381|Homo sapiens SH2/SH3 adaptor protein
NCK-beta protein.
Length = 381
Score = 89.4 bits (212), Expect = 7e-17
Identities = 50/142 (35%), Positives = 76/142 (53%), Gaps = 13/142 (9%)
Query: 1167 SYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTS 1226
+Y A ++LSL+KG + V +K GWW G N Q+GWFP++Y VL+ +
Sbjct: 122 AYVAEREDELSLVKGSRVTVMEKCSDGWWRGSY-----NGQIGWFPSNY--VLEEVDEAA 174
Query: 1227 GRTTPVLSSKMDALPT----ETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQ-DPA 1281
+ LS + A + V+ V LYP+++ +EL+FEK + + V ++ + DP
Sbjct: 175 AESPSFLSLRKGASLSNGQGSRVLHVVQTLYPFSSVTEEELNFEKGETMEVIEKPENDPE 234
Query: 1282 WWQ-GELRGMVGLFPSNYVTKL 1302
WW+ RG VGL P NYV L
Sbjct: 235 WWKCKNARGQVGLVPKNYVVVL 256
Score = 49.6 bits (113), Expect = 7e-05
Identities = 21/52 (40%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Query: 1253 YPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
+ Y A+ DELS K + V ++ D WW+G G +G FPSNYV + V+
Sbjct: 121 FAYVAEREDELSLVKGSRVTVMEKCSD-GWWRGSYNGQIGWFPSNYVLEEVD 171
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 1008 YPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYVSREAAPAA 1060
+ Y + +L G R+ V+ + D WW G + G FPSNYV E AA
Sbjct: 121 FAYVAEREDELSLVKGSRVTVMEKCSDGWWRGSYNGQIGWFPSNYVLEEVDEAA 174
Score = 38.7 bits (86), Expect = 0.14
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 6/82 (7%)
Query: 1155 GRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKA--DSGWWEGELQAKGRNRQVGWFP 1212
G R +VQ L +++ + E+L+ KG+ + V +K D WW + K QVG P
Sbjct: 194 GSRVLHVVQTLYPFSSVTEEELNFEKGETMEVIEKPENDPEWW----KCKNARGQVGLVP 249
Query: 1213 ASYVKVLQSSGRTSGRTTPVLS 1234
+YV VL P +S
Sbjct: 250 KNYVVVLSDGPALHPAHAPQIS 271
Score = 38.7 bits (86), Expect = 0.14
Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 4/49 (8%)
Query: 1008 YPYSSSEPGDLVFEAGERIEVVRR---DGDWWTGR-IGARTGIFPSNYV 1052
YP+SS +L FE GE +EV+ + D +WW + + G+ P NYV
Sbjct: 205 YPFSSVTEEELNFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYV 253
Score = 36.3 bits (80), Expect = 0.72
Identities = 32/135 (23%), Positives = 55/135 (40%), Gaps = 7/135 (5%)
Query: 1005 IASYPYSSSEPGDL-VFEAGERIEVVRRDGDWWTGRIGA-RTGIFPSNYVSREAAPAATS 1062
IA + Y++ + +L + + ER+ ++ WW R A RTG PSNYV R+ + S
Sbjct: 8 IAKWDYTAQQDQELDIKKVNERLWLLDDSKTWWRVRNAANRTGYVPSNYVERKNSLKKGS 67
Query: 1063 XXXXXXXXXXXXXXXXXXXXXXTSP-PNTTPPIPA----SQLIWTSNELAYTSVTFLLAQ 1117
SP P+T PA + I+ N A+ ++ +
Sbjct: 68 LVKNLKDTLGLGKTRRKTSARDASPTPSTDAEYPANGSGADRIYDLNIPAFVKFAYVAER 127
Query: 1118 DQKSSTPISSEVAMI 1132
+ + S S V ++
Sbjct: 128 EDELSLVKGSRVTVM 142
Score = 33.1 bits (72), Expect = 6.7
Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 6/62 (9%)
Query: 1242 TETVIDKVVALYPYTAQNADELSFEK-DDIIAVTDRSQDPAWWQ-GELRGMVGLFPSNYV 1299
TE VI V+A + YTAQ EL +K ++ + + D S+ WW+ G PSNYV
Sbjct: 2 TEEVI--VIAKWDYTAQQDQELDIKKVNERLWLLDDSK--TWWRVRNAANRTGYVPSNYV 57
Query: 1300 TK 1301
+
Sbjct: 58 ER 59
>AC009505-1|AAY24332.1| 304|Homo sapiens unknown protein.
Length = 304
Score = 89.4 bits (212), Expect = 7e-17
Identities = 50/142 (35%), Positives = 76/142 (53%), Gaps = 13/142 (9%)
Query: 1167 SYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTS 1226
+Y A ++LSL+KG + V +K GWW G N Q+GWFP++Y VL+ +
Sbjct: 45 AYVAEREDELSLVKGSRVTVMEKCSDGWWRGSY-----NGQIGWFPSNY--VLEEVDEAA 97
Query: 1227 GRTTPVLSSKMDALPT----ETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQ-DPA 1281
+ LS + A + V+ V LYP+++ +EL+FEK + + V ++ + DP
Sbjct: 98 AESPSFLSLRKGASLSNGQGSRVLHVVQTLYPFSSVTEEELNFEKGETMEVIEKPENDPE 157
Query: 1282 WWQ-GELRGMVGLFPSNYVTKL 1302
WW+ RG VGL P NYV L
Sbjct: 158 WWKCKNARGQVGLVPKNYVVVL 179
Score = 49.6 bits (113), Expect = 7e-05
Identities = 21/52 (40%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Query: 1253 YPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
+ Y A+ DELS K + V ++ D WW+G G +G FPSNYV + V+
Sbjct: 44 FAYVAEREDELSLVKGSRVTVMEKCSD-GWWRGSYNGQIGWFPSNYVLEEVD 94
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 1008 YPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYVSREAAPAA 1060
+ Y + +L G R+ V+ + D WW G + G FPSNYV E AA
Sbjct: 44 FAYVAEREDELSLVKGSRVTVMEKCSDGWWRGSYNGQIGWFPSNYVLEEVDEAA 97
Score = 38.7 bits (86), Expect = 0.14
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 6/82 (7%)
Query: 1155 GRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKA--DSGWWEGELQAKGRNRQVGWFP 1212
G R +VQ L +++ + E+L+ KG+ + V +K D WW + K QVG P
Sbjct: 117 GSRVLHVVQTLYPFSSVTEEELNFEKGETMEVIEKPENDPEWW----KCKNARGQVGLVP 172
Query: 1213 ASYVKVLQSSGRTSGRTTPVLS 1234
+YV VL P +S
Sbjct: 173 KNYVVVLSDGPALHPAHAPQIS 194
Score = 38.7 bits (86), Expect = 0.14
Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 4/49 (8%)
Query: 1008 YPYSSSEPGDLVFEAGERIEVVRR---DGDWWTGR-IGARTGIFPSNYV 1052
YP+SS +L FE GE +EV+ + D +WW + + G+ P NYV
Sbjct: 128 YPFSSVTEEELNFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYV 176
>AY007161-1|AAG02009.1| 534|Homo sapiens protein ( Homo sapiens
clone CDABP0131 mRNA sequence. ).
Length = 534
Score = 87.4 bits (207), Expect = 3e-16
Identities = 43/96 (44%), Positives = 60/96 (62%), Gaps = 1/96 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLD 65
W + + + E F L PVNG +TG AK+ M++S+LP VLG+IW LAD + DG LD
Sbjct: 439 WVV-GKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLD 497
Query: 66 LKEFSIACKIINLKLRGLEVPKMLPPSLIASLSPTG 101
+EF++A +I +KL G E+P LPP L+ S G
Sbjct: 498 DEEFALANHLIKVKLEGHELPADLPPHLVPPSSAWG 533
Score = 72.1 bits (169), Expect = 1e-11
Identities = 38/94 (40%), Positives = 54/94 (57%), Gaps = 2/94 (2%)
Query: 353 MEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADG 412
+EW V + K Y ++F G +G A+ M++S+LP L +IW LAD+D DG
Sbjct: 437 VEWVVGK-DKPTYDEIFYTLSPVN-GKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDG 494
Query: 413 KLGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L EEF LA +L + +G +PA LPP L+PP
Sbjct: 495 LLDDEEFALANHLIKVKLEGHELPADLPPHLVPP 528
>BC051823-1|AAH51823.1| 541|Homo sapiens EH-domain containing 4
protein.
Length = 541
Score = 87.0 bits (206), Expect = 4e-16
Identities = 40/91 (43%), Positives = 59/91 (64%), Gaps = 1/91 (1%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGK 63
+ W + A + + E F L P+NG ++G AK+ M+ S+LP VLG+IW LAD + DG
Sbjct: 440 EEWVV-AKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGM 498
Query: 64 LDLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
LD +EF++A +I +KL G E+P LPP L+
Sbjct: 499 LDEEEFALAKHLIKIKLDGYELPSSLPPHLV 529
Score = 70.1 bits (164), Expect = 5e-11
Identities = 38/93 (40%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Query: 354 EWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGK 413
EW V + + + Y +LF G SG A+ M+ S+LP L +IW LAD D DG
Sbjct: 441 EWVVAKDKPV-YDELFYTLSPIN-GKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGM 498
Query: 414 LGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L EEF LA +L + G +P+ LPP L+PP
Sbjct: 499 LDEEEFALAKHLIKIKLDGYELPSSLPPHLVPP 531
>BC006287-1|AAH06287.1| 541|Homo sapiens EH-domain containing 4
protein.
Length = 541
Score = 87.0 bits (206), Expect = 4e-16
Identities = 40/91 (43%), Positives = 59/91 (64%), Gaps = 1/91 (1%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGK 63
+ W + A + + E F L P+NG ++G AK+ M+ S+LP VLG+IW LAD + DG
Sbjct: 440 EEWVV-AKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGM 498
Query: 64 LDLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
LD +EF++A +I +KL G E+P LPP L+
Sbjct: 499 LDEEEFALAKHLIKIKLDGYELPSSLPPHLV 529
Score = 70.1 bits (164), Expect = 5e-11
Identities = 38/93 (40%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Query: 354 EWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGK 413
EW V + + + Y +LF G SG A+ M+ S+LP L +IW LAD D DG
Sbjct: 441 EWVVAKDKPV-YDELFYTLSPIN-GKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGM 498
Query: 414 LGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L EEF LA +L + G +P+ LPP L+PP
Sbjct: 499 LDEEEFALAKHLIKIKLDGYELPSSLPPHLVPP 531
>AF454953-1|AAL51079.1| 541|Homo sapiens EH domain-containing
protein-4 protein.
Length = 541
Score = 87.0 bits (206), Expect = 4e-16
Identities = 40/91 (43%), Positives = 59/91 (64%), Gaps = 1/91 (1%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGK 63
+ W + A + + E F L P+NG ++G AK+ M+ S+LP VLG+IW LAD + DG
Sbjct: 440 EEWVV-AKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGM 498
Query: 64 LDLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
LD +EF++A +I +KL G E+P LPP L+
Sbjct: 499 LDEEEFALAKHLIKIKLDGYELPSSLPPHLV 529
Score = 70.1 bits (164), Expect = 5e-11
Identities = 38/93 (40%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Query: 354 EWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGK 413
EW V + + + Y +LF G SG A+ M+ S+LP L +IW LAD D DG
Sbjct: 441 EWVVAKDKPV-YDELFYTLSPIN-GKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGM 498
Query: 414 LGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L EEF LA +L + G +P+ LPP L+PP
Sbjct: 499 LDEEEFALAKHLIKIKLDGYELPSSLPPHLVPP 531
>AF323924-1|AAK11599.1| 541|Homo sapiens hepatocellular
carcinoma-associated protein HCA11 protein.
Length = 541
Score = 87.0 bits (206), Expect = 4e-16
Identities = 40/91 (43%), Positives = 59/91 (64%), Gaps = 1/91 (1%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGK 63
+ W + A + + E F L P+NG ++G AK+ M+ S+LP VLG+IW LAD + DG
Sbjct: 440 EEWVV-AKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGM 498
Query: 64 LDLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
LD +EF++A +I +KL G E+P LPP L+
Sbjct: 499 LDEEEFALAKHLIKIKLDGYELPSSLPPHLV 529
Score = 70.1 bits (164), Expect = 5e-11
Identities = 38/93 (40%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Query: 354 EWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGK 413
EW V + + + Y +LF G SG A+ M+ S+LP L +IW LAD D DG
Sbjct: 441 EWVVAKDKPV-YDELFYTLSPIN-GKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGM 498
Query: 414 LGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L EEF LA +L + G +P+ LPP L+PP
Sbjct: 499 LDEEEFALAKHLIKIKLDGYELPSSLPPHLVPP 531
>AF181265-1|AAF40472.1| 482|Homo sapiens EH domain containing 4
protein.
Length = 482
Score = 87.0 bits (206), Expect = 4e-16
Identities = 40/91 (43%), Positives = 59/91 (64%), Gaps = 1/91 (1%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGK 63
+ W + A + + E F L P+NG ++G AK+ M+ S+LP VLG+IW LAD + DG
Sbjct: 381 EEWVV-AKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGM 439
Query: 64 LDLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
LD +EF++A +I +KL G E+P LPP L+
Sbjct: 440 LDEEEFALAKHLIKIKLDGYELPSSLPPHLV 470
Score = 70.1 bits (164), Expect = 5e-11
Identities = 38/93 (40%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Query: 354 EWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGK 413
EW V + + + Y +LF G SG A+ M+ S+LP L +IW LAD D DG
Sbjct: 382 EWVVAKDKPV-YDELFYTLSPIN-GKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGM 439
Query: 414 LGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L EEF LA +L + G +P+ LPP L+PP
Sbjct: 440 LDEEEFALAKHLIKIKLDGYELPSSLPPHLVPP 472
>BC104825-1|AAI04826.1| 534|Homo sapiens EH-domain containing 1
protein.
Length = 534
Score = 86.2 bits (204), Expect = 7e-16
Identities = 41/89 (46%), Positives = 58/89 (65%), Gaps = 1/89 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLD 65
W + + + E F L PVNG +TG AK+ M++S+LP VLG+IW LAD + DG LD
Sbjct: 439 WVV-GKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLD 497
Query: 66 LKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF++A +I +KL G E+P LPP L+
Sbjct: 498 DEEFALANHLIKVKLEGHELPADLPPHLV 526
Score = 72.1 bits (169), Expect = 1e-11
Identities = 38/94 (40%), Positives = 54/94 (57%), Gaps = 2/94 (2%)
Query: 353 MEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADG 412
+EW V + K Y ++F G +G A+ M++S+LP L +IW LAD+D DG
Sbjct: 437 VEWVVGK-DKPTYDEIFYTLSPVN-GKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDG 494
Query: 413 KLGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L EEF LA +L + +G +PA LPP L+PP
Sbjct: 495 LLDDEEFALANHLIKVKLEGHELPADLPPHLVPP 528
>BC104799-1|AAI04800.1| 534|Homo sapiens EH-domain containing 1
protein.
Length = 534
Score = 86.2 bits (204), Expect = 7e-16
Identities = 41/89 (46%), Positives = 58/89 (65%), Gaps = 1/89 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLD 65
W + + + E F L PVNG +TG AK+ M++S+LP VLG+IW LAD + DG LD
Sbjct: 439 WVV-GKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLD 497
Query: 66 LKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF++A +I +KL G E+P LPP L+
Sbjct: 498 DEEFALANHLIKVKLEGHELPADLPPHLV 526
Score = 72.1 bits (169), Expect = 1e-11
Identities = 38/94 (40%), Positives = 54/94 (57%), Gaps = 2/94 (2%)
Query: 353 MEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADG 412
+EW V + K Y ++F G +G A+ M++S+LP L +IW LAD+D DG
Sbjct: 437 VEWVVGK-DKPTYDEIFYTLSPVN-GKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDG 494
Query: 413 KLGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L EEF LA +L + +G +PA LPP L+PP
Sbjct: 495 LLDDEEFALANHLIKVKLEGHELPADLPPHLVPP 528
>AF001434-1|AAB81204.1| 534|Homo sapiens Hpast protein.
Length = 534
Score = 86.2 bits (204), Expect = 7e-16
Identities = 41/89 (46%), Positives = 58/89 (65%), Gaps = 1/89 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLD 65
W + + + E F L PVNG +TG AK+ M++S+LP VLG+IW LAD + DG LD
Sbjct: 439 WVV-GKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDGLLD 497
Query: 66 LKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF++A +I +KL G E+P LPP L+
Sbjct: 498 DEEFALANHLIKVKLEGHELPADLPPHLV 526
Score = 72.1 bits (169), Expect = 1e-11
Identities = 38/94 (40%), Positives = 54/94 (57%), Gaps = 2/94 (2%)
Query: 353 MEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADG 412
+EW V + K Y ++F G +G A+ M++S+LP L +IW LAD+D DG
Sbjct: 437 VEWVVGK-DKPTYDEIFYTLSPVN-GKITGANAKKEMVKSKLPNTVLGKIWKLADVDKDG 494
Query: 413 KLGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L EEF LA +L + +G +PA LPP L+PP
Sbjct: 495 LLDDEEFALANHLIKVKLEGHELPADLPPHLVPP 528
>AY340592-1|AAQ19991.1| 135|Homo sapiens intersectin 1 isoform 8
protein.
Length = 135
Score = 85.0 bits (201), Expect = 2e-15
Identities = 48/125 (38%), Positives = 69/125 (55%), Gaps = 24/125 (19%)
Query: 928 RGQSGWFPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDP 987
+GQ GWFP+SYV+ ++ P + T ++ +S+ +L V P
Sbjct: 7 QGQKGWFPKSYVKLISGP----------IRKSTSMDS--------GSSESPASLKRVASP 48
Query: 988 GRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIF 1047
++PV GE +IA Y Y SSE GDL F+ G+ I V ++DGDWWTG +G + G+F
Sbjct: 49 A---AKPVV---SGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTVGDKAGVF 102
Query: 1048 PSNYV 1052
PSNYV
Sbjct: 103 PSNYV 107
Score = 73.3 bits (172), Expect = 5e-12
Identities = 41/114 (35%), Positives = 61/114 (53%), Gaps = 15/114 (13%)
Query: 1194 WWEGELQAKGRNRQVGWFPASYVKVL-----QSSGRTSGRTTPVLSSKMDALPTETVI-- 1246
WW GE+Q Q GWFP SYVK++ +S+ SG + S K A P +
Sbjct: 1 WWFGEVQG-----QKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVASPAAKPVVS 55
Query: 1247 -DKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
++ +A+Y Y + +L+F++ D+I VT + D WW G + G+FPSNYV
Sbjct: 56 GEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGD--WWTGTVGDKAGVFPSNYV 107
Score = 41.5 bits (93), Expect = 0.019
Identities = 26/68 (38%), Positives = 39/68 (57%), Gaps = 9/68 (13%)
Query: 1165 LASYTATSPEQ--LSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSS 1222
+A YT S EQ L+ +G +++V KK D WW G + K G FP++YV++ S
Sbjct: 60 IAMYTYESSEQGDLTFQQGDVILVTKK-DGDWWTGTVGDKA-----GVFPSNYVRLKDSE 113
Query: 1223 GR-TSGRT 1229
G T+G+T
Sbjct: 114 GSGTAGKT 121
>BC131590-1|AAI31591.1| 754|Homo sapiens EPS15L1 protein protein.
Length = 754
Score = 84.2 bits (199), Expect = 3e-15
Identities = 38/89 (42%), Positives = 56/89 (62%)
Query: 6 WTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLD 65
W ++ E AKF F +L P+NG L+G++ K ++ S+LP VLG++W L+D + DG LD
Sbjct: 121 WAVRVEEKAKFDGIFESLLPINGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLD 180
Query: 66 LKEFSIACKIINLKLRGLEVPKMLPPSLI 94
EF++A ++ L VP LPPSLI
Sbjct: 181 RDEFAVAMHLVYRALEKEPVPSALPPSLI 209
Score = 80.6 bits (190), Expect = 3e-14
Identities = 39/102 (38%), Positives = 62/102 (60%), Gaps = 3/102 (2%)
Query: 347 VMSPPPME--WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWA 404
+++PP E W V +K K+ +F + G SG + + +++ S+LP L ++W
Sbjct: 111 MVTPPSAEAHWAVRVEEKAKFDGIFESL-LPINGLLSGDKVKPVLMNSKLPLDVLGRVWD 169
Query: 405 LADLDADGKLGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L+D+D DG L +EF +AM+L +A + EPVP+ LPP LIPP
Sbjct: 170 LSDIDKDGHLDRDEFAVAMHLVYRALEKEPVPSALPPSLIPP 211
Score = 77.0 bits (181), Expect = 4e-13
Identities = 38/97 (39%), Positives = 56/97 (57%), Gaps = 1/97 (1%)
Query: 351 PPMEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDA 410
P + W VP K+++ ++F TD G SG + + I + S L Q LA IWALAD
Sbjct: 265 PTVNWVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQ 324
Query: 411 DGKLGCEEFVLAMY-LCEKATQGEPVPARLPPELIPP 446
GKL ++F LAMY + +K ++G P L P+++PP
Sbjct: 325 TGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVPP 361
Score = 56.8 bits (131), Expect = 5e-07
Identities = 27/91 (29%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Query: 6 WTIQAHEHAKFSEHFRNLG-PVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + + +F E F ++G ++G++ K + S L +L IW+LADT GKL
Sbjct: 269 WVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQTGKL 328
Query: 65 DLKEFSIACKIINLKL-RGLEVPKMLPPSLI 94
+F++A I K+ +G++ P++L P ++
Sbjct: 329 SKDQFALAMYFIQQKVSKGIDPPQVLSPDMV 359
Score = 42.3 bits (95), Expect = 0.011
Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Query: 16 FSEHFRNLGPV-NGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLDLKEFSIACK 74
+ +++ + P G + +A F+ +S L +LG+IW LAD G LD + F +A +
Sbjct: 19 YESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVALR 78
Query: 75 IINLKLRGLEV 85
++ G EV
Sbjct: 79 LVACAQSGHEV 89
Score = 38.3 bits (85), Expect = 0.18
Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 2/96 (2%)
Query: 352 PMEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDAD 411
P+ +P L Y + D A TG ++A + +S L L +IW LAD +
Sbjct: 7 PLSQQIPTGNSL-YESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGK 65
Query: 412 GKLGCEEFVLAMYLCEKATQGEPVP-ARLPPELIPP 446
G L + F +A+ L A G V + L + PP
Sbjct: 66 GFLDKQGFYVALRLVACAQSGHEVTLSNLNLSMPPP 101
>AF110265-1|AAF21930.1| 864|Homo sapiens epidermal growth factor
receptor substrate EPS15R protein.
Length = 864
Score = 84.2 bits (199), Expect = 3e-15
Identities = 38/89 (42%), Positives = 56/89 (62%)
Query: 6 WTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLD 65
W ++ E AKF F +L P+NG L+G++ K ++ S+LP VLG++W L+D + DG LD
Sbjct: 121 WAVRVEEKAKFDGIFESLLPINGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLD 180
Query: 66 LKEFSIACKIINLKLRGLEVPKMLPPSLI 94
EF++A ++ L VP LPPSLI
Sbjct: 181 RDEFAVAMHLVYRALEKEPVPSALPPSLI 209
Score = 80.6 bits (190), Expect = 3e-14
Identities = 39/102 (38%), Positives = 62/102 (60%), Gaps = 3/102 (2%)
Query: 347 VMSPPPME--WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWA 404
+++PP E W V +K K+ +F + G SG + + +++ S+LP L ++W
Sbjct: 111 MVTPPSAEAHWAVRVEEKAKFDGIFESL-LPINGLLSGDKVKPVLMNSKLPLDVLGRVWD 169
Query: 405 LADLDADGKLGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L+D+D DG L +EF +AM+L +A + EPVP+ LPP LIPP
Sbjct: 170 LSDIDKDGHLDRDEFAVAMHLVYRALEKEPVPSALPPSLIPP 211
Score = 77.0 bits (181), Expect = 4e-13
Identities = 38/97 (39%), Positives = 56/97 (57%), Gaps = 1/97 (1%)
Query: 351 PPMEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDA 410
P + W VP K+++ ++F TD G SG + + I + S L Q LA IWALAD
Sbjct: 265 PTVNWVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQ 324
Query: 411 DGKLGCEEFVLAMY-LCEKATQGEPVPARLPPELIPP 446
GKL ++F LAMY + +K ++G P L P+++PP
Sbjct: 325 TGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVPP 361
Score = 56.8 bits (131), Expect = 5e-07
Identities = 27/91 (29%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Query: 6 WTIQAHEHAKFSEHFRNLG-PVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + + +F E F ++G ++G++ K + S L +L IW+LADT GKL
Sbjct: 269 WVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQTGKL 328
Query: 65 DLKEFSIACKIINLKL-RGLEVPKMLPPSLI 94
+F++A I K+ +G++ P++L P ++
Sbjct: 329 SKDQFALAMYFIQQKVSKGIDPPQVLSPDMV 359
Score = 42.3 bits (95), Expect = 0.011
Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Query: 16 FSEHFRNLGPV-NGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLDLKEFSIACK 74
+ +++ + P G + +A F+ +S L +LG+IW LAD G LD + F +A +
Sbjct: 19 YESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVALR 78
Query: 75 IINLKLRGLEV 85
++ G EV
Sbjct: 79 LVACAQSGHEV 89
Score = 38.3 bits (85), Expect = 0.18
Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 2/96 (2%)
Query: 352 PMEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDAD 411
P+ +P L Y + D A TG ++A + +S L L +IW LAD +
Sbjct: 7 PLSQQIPTGNSL-YESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGK 65
Query: 412 GKLGCEEFVLAMYLCEKATQGEPVP-ARLPPELIPP 446
G L + F +A+ L A G V + L + PP
Sbjct: 66 GFLDKQGFYVALRLVACAQSGHEVTLSNLNLSMPPP 101
>AB015346-1|BAA88118.1| 864|Homo sapiens Eps15R protein.
Length = 864
Score = 84.2 bits (199), Expect = 3e-15
Identities = 38/89 (42%), Positives = 56/89 (62%)
Query: 6 WTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLD 65
W ++ E AKF F +L P+NG L+G++ K ++ S+LP VLG++W L+D + DG LD
Sbjct: 121 WAVRVEEKAKFDGIFESLLPINGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLD 180
Query: 66 LKEFSIACKIINLKLRGLEVPKMLPPSLI 94
EF++A ++ L VP LPPSLI
Sbjct: 181 RDEFAVAMHLVYRALEKEPVPSALPPSLI 209
Score = 80.6 bits (190), Expect = 3e-14
Identities = 39/102 (38%), Positives = 62/102 (60%), Gaps = 3/102 (2%)
Query: 347 VMSPPPME--WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWA 404
+++PP E W V +K K+ +F + G SG + + +++ S+LP L ++W
Sbjct: 111 MVTPPSAEAHWAVRVEEKAKFDGIFESL-LPINGLLSGDKVKPVLMNSKLPLDVLGRVWD 169
Query: 405 LADLDADGKLGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L+D+D DG L +EF +AM+L +A + EPVP+ LPP LIPP
Sbjct: 170 LSDIDKDGHLDRDEFAVAMHLVYRALEKEPVPSALPPSLIPP 211
Score = 77.0 bits (181), Expect = 4e-13
Identities = 38/97 (39%), Positives = 56/97 (57%), Gaps = 1/97 (1%)
Query: 351 PPMEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDA 410
P + W VP K+++ ++F TD G SG + + I + S L Q LA IWALAD
Sbjct: 265 PTVNWVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQ 324
Query: 411 DGKLGCEEFVLAMY-LCEKATQGEPVPARLPPELIPP 446
GKL ++F LAMY + +K ++G P L P+++PP
Sbjct: 325 TGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVPP 361
Score = 56.8 bits (131), Expect = 5e-07
Identities = 27/91 (29%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Query: 6 WTIQAHEHAKFSEHFRNLG-PVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + + +F E F ++G ++G++ K + S L +L IW+LADT GKL
Sbjct: 269 WVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQTGKL 328
Query: 65 DLKEFSIACKIINLKL-RGLEVPKMLPPSLI 94
+F++A I K+ +G++ P++L P ++
Sbjct: 329 SKDQFALAMYFIQQKVSKGIDPPQVLSPDMV 359
Score = 42.3 bits (95), Expect = 0.011
Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Query: 16 FSEHFRNLGPV-NGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLDLKEFSIACK 74
+ +++ + P G + +A F+ +S L +LG+IW LAD G LD + F +A +
Sbjct: 19 YESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVALR 78
Query: 75 IINLKLRGLEV 85
++ G EV
Sbjct: 79 LVACAQSGHEV 89
Score = 38.3 bits (85), Expect = 0.18
Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 2/96 (2%)
Query: 352 PMEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDAD 411
P+ +P L Y + D A TG ++A + +S L L +IW LAD +
Sbjct: 7 PLSQQIPTGNSL-YESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGK 65
Query: 412 GKLGCEEFVLAMYLCEKATQGEPVP-ARLPPELIPP 446
G L + F +A+ L A G V + L + PP
Sbjct: 66 GFLDKQGFYVALRLVACAQSGHEVTLSNLNLSMPPP 101
>Z29064-1|CAA82305.1| 896|Homo sapiens AF-1p protein.
Length = 896
Score = 83.8 bits (198), Expect = 4e-15
Identities = 36/90 (40%), Positives = 57/90 (63%)
Query: 5 PWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
PW ++ + AK+ F +L PVNG L+G++ K +L S+LP +LG++W L+D + DG L
Sbjct: 121 PWAVKPEDKAKYDAIFDSLSPVNGFLSGDKVKPVLLNSKLPVDILGRVWELSDIDHDGML 180
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
D EF++A ++ L VP LPP+L+
Sbjct: 181 DRDEFAVAMFLVYCALEKEPVPMSLPPALV 210
Score = 81.0 bits (191), Expect = 3e-14
Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
Query: 339 TSPEVPMGVMSPPPMEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQS 398
TS + + S + W V K KY +F++ G SG + + ++L S+LP
Sbjct: 106 TSSPLLISGTSAAELPWAVKPEDKAKYDAIFDSLSPVN-GFLSGDKVKPVLLNSKLPVDI 164
Query: 399 LAQIWALADLDADGKLGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L ++W L+D+D DG L +EF +AM+L A + EPVP LPP L+PP
Sbjct: 165 LGRVWELSDIDHDGMLDRDEFAVAMFLVYCALEKEPVPMSLPPALVPP 212
Score = 72.1 bits (169), Expect = 1e-11
Identities = 40/106 (37%), Positives = 58/106 (54%), Gaps = 2/106 (1%)
Query: 343 VPMGVMSPPPME-WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQ 401
+P ++ P + W V +K KY ++F TD+ G SG + R I L++ LP LA
Sbjct: 205 LPPALVPPSKRKTWVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAH 264
Query: 402 IWALADLDADGKLGCEEFVLAMYL-CEKATQGEPVPARLPPELIPP 446
IW+L D GKL ++F LA +L +K +G P L PE+IPP
Sbjct: 265 IWSLCDTKDCGKLSKDQFALAFHLISQKLIKGIDPPHVLTPEMIPP 310
Score = 60.5 bits (140), Expect = 4e-08
Identities = 31/91 (34%), Positives = 52/91 (57%), Gaps = 2/91 (2%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + E AK+ E F ++G ++G + + L++ LP +L IWSL DT GKL
Sbjct: 218 WVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAHIWSLCDTKDCGKL 277
Query: 65 DLKEFSIACKIINLKL-RGLEVPKMLPPSLI 94
+F++A +I+ KL +G++ P +L P +I
Sbjct: 278 SKDQFALAFHLISQKLIKGIDPPHVLTPEMI 308
Score = 52.0 bits (119), Expect = 1e-05
Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 16 FSEHFRNLGPVN-GNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLDLKEFSIACK 74
+ +++R + N G + A F+ +S LP +LG+IW LADT+ G L+ +EF +A +
Sbjct: 19 YEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALR 78
Query: 75 IINLKLRGLEV 85
++ GLEV
Sbjct: 79 LVACAQNGLEV 89
Score = 44.8 bits (101), Expect = 0.002
Identities = 26/82 (31%), Positives = 37/82 (45%)
Query: 365 YTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLGCEEFVLAMY 424
Y + + D TG + A + + +S LP L +IW LAD D G L +EF +A+
Sbjct: 19 YEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALR 78
Query: 425 LCEKATQGEPVPARLPPELIPP 446
L A G V +PP
Sbjct: 79 LVACAQNGLEVSLSSLNLAVPP 100
>U07707-1|AAA52101.1| 896|Homo sapiens epidermal growth factor
receptor substrate protein.
Length = 896
Score = 83.8 bits (198), Expect = 4e-15
Identities = 36/90 (40%), Positives = 57/90 (63%)
Query: 5 PWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
PW ++ + AK+ F +L PVNG L+G++ K +L S+LP +LG++W L+D + DG L
Sbjct: 121 PWAVKPEDKAKYDAIFDSLSPVNGFLSGDKVKPVLLNSKLPVDILGRVWELSDIDHDGML 180
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
D EF++A ++ L VP LPP+L+
Sbjct: 181 DRDEFAVAMFLVYCALEKEPVPMSLPPALV 210
Score = 81.0 bits (191), Expect = 3e-14
Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
Query: 339 TSPEVPMGVMSPPPMEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQS 398
TS + + S + W V K KY +F++ G SG + + ++L S+LP
Sbjct: 106 TSSPLLISGTSAAELPWAVKPEDKAKYDAIFDSLSPVN-GFLSGDKVKPVLLNSKLPVDI 164
Query: 399 LAQIWALADLDADGKLGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L ++W L+D+D DG L +EF +AM+L A + EPVP LPP L+PP
Sbjct: 165 LGRVWELSDIDHDGMLDRDEFAVAMFLVYCALEKEPVPMSLPPALVPP 212
Score = 72.1 bits (169), Expect = 1e-11
Identities = 40/106 (37%), Positives = 58/106 (54%), Gaps = 2/106 (1%)
Query: 343 VPMGVMSPPPME-WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQ 401
+P ++ P + W V +K KY ++F TD+ G SG + R I L++ LP LA
Sbjct: 205 LPPALVPPSKRKTWVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAH 264
Query: 402 IWALADLDADGKLGCEEFVLAMYL-CEKATQGEPVPARLPPELIPP 446
IW+L D GKL ++F LA +L +K +G P L PE+IPP
Sbjct: 265 IWSLCDTKDCGKLSKDQFALAFHLISQKLIKGIDPPHVLTPEMIPP 310
Score = 60.5 bits (140), Expect = 4e-08
Identities = 31/91 (34%), Positives = 52/91 (57%), Gaps = 2/91 (2%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + E AK+ E F ++G ++G + + L++ LP +L IWSL DT GKL
Sbjct: 218 WVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAHIWSLCDTKDCGKL 277
Query: 65 DLKEFSIACKIINLKL-RGLEVPKMLPPSLI 94
+F++A +I+ KL +G++ P +L P +I
Sbjct: 278 SKDQFALAFHLISQKLIKGIDPPHVLTPEMI 308
Score = 52.0 bits (119), Expect = 1e-05
Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 16 FSEHFRNLGPVN-GNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLDLKEFSIACK 74
+ +++R + N G + A F+ +S LP +LG+IW LADT+ G L+ +EF +A +
Sbjct: 19 YEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALR 78
Query: 75 IINLKLRGLEV 85
++ GLEV
Sbjct: 79 LVACAQNGLEV 89
Score = 44.8 bits (101), Expect = 0.002
Identities = 26/82 (31%), Positives = 37/82 (45%)
Query: 365 YTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLGCEEFVLAMY 424
Y + + D TG + A + + +S LP L +IW LAD D G L +EF +A+
Sbjct: 19 YEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALR 78
Query: 425 LCEKATQGEPVPARLPPELIPP 446
L A G V +PP
Sbjct: 79 LVACAQNGLEVSLSSLNLAVPP 100
>DQ367924-1|ABD34786.1| 896|Homo sapiens epidermal growth factor
receptor pathway substrate 15 protein.
Length = 896
Score = 83.8 bits (198), Expect = 4e-15
Identities = 36/90 (40%), Positives = 57/90 (63%)
Query: 5 PWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
PW ++ + AK+ F +L PVNG L+G++ K +L S+LP +LG++W L+D + DG L
Sbjct: 121 PWAVKPEDKAKYDAIFDSLSPVNGFLSGDKVKPVLLNSKLPVDILGRVWELSDIDHDGML 180
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
D EF++A ++ L VP LPP+L+
Sbjct: 181 DRDEFAVAMFLVYCALEKEPVPMSLPPALV 210
Score = 81.0 bits (191), Expect = 3e-14
Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
Query: 339 TSPEVPMGVMSPPPMEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQS 398
TS + + S + W V K KY +F++ G SG + + ++L S+LP
Sbjct: 106 TSSPLLISGTSAAELPWAVKPEDKAKYDAIFDSLSPVN-GFLSGDKVKPVLLNSKLPVDI 164
Query: 399 LAQIWALADLDADGKLGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L ++W L+D+D DG L +EF +AM+L A + EPVP LPP L+PP
Sbjct: 165 LGRVWELSDIDHDGMLDRDEFAVAMFLVYCALEKEPVPMSLPPALVPP 212
Score = 72.1 bits (169), Expect = 1e-11
Identities = 40/106 (37%), Positives = 58/106 (54%), Gaps = 2/106 (1%)
Query: 343 VPMGVMSPPPME-WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQ 401
+P ++ P + W V +K KY ++F TD+ G SG + R I L++ LP LA
Sbjct: 205 LPPALVPPSKRKTWVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAH 264
Query: 402 IWALADLDADGKLGCEEFVLAMYL-CEKATQGEPVPARLPPELIPP 446
IW+L D GKL ++F LA +L +K +G P L PE+IPP
Sbjct: 265 IWSLCDTKDCGKLSKDQFALAFHLISQKLIKGIDPPHVLTPEMIPP 310
Score = 60.5 bits (140), Expect = 4e-08
Identities = 31/91 (34%), Positives = 52/91 (57%), Gaps = 2/91 (2%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + E AK+ E F ++G ++G + + L++ LP +L IWSL DT GKL
Sbjct: 218 WVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAHIWSLCDTKDCGKL 277
Query: 65 DLKEFSIACKIINLKL-RGLEVPKMLPPSLI 94
+F++A +I+ KL +G++ P +L P +I
Sbjct: 278 SKDQFALAFHLISQKLIKGIDPPHVLTPEMI 308
Score = 52.0 bits (119), Expect = 1e-05
Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 16 FSEHFRNLGPVN-GNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLDLKEFSIACK 74
+ +++R + N G + A F+ +S LP +LG+IW LADT+ G L+ +EF +A +
Sbjct: 19 YEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALR 78
Query: 75 IINLKLRGLEV 85
++ GLEV
Sbjct: 79 LVACAQNGLEV 89
Score = 44.8 bits (101), Expect = 0.002
Identities = 26/82 (31%), Positives = 37/82 (45%)
Query: 365 YTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLGCEEFVLAMY 424
Y + + D TG + A + + +S LP L +IW LAD D G L +EF +A+
Sbjct: 19 YEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALR 78
Query: 425 LCEKATQGEPVPARLPPELIPP 446
L A G V +PP
Sbjct: 79 LVACAQNGLEVSLSSLNLAVPP 100
>BC054006-1|AAH54006.1| 762|Homo sapiens EPS15 protein protein.
Length = 762
Score = 83.8 bits (198), Expect = 4e-15
Identities = 36/90 (40%), Positives = 57/90 (63%)
Query: 5 PWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
PW ++ + AK+ F +L PVNG L+G++ K +L S+LP +LG++W L+D + DG L
Sbjct: 121 PWAVKPEDKAKYDAIFDSLSPVNGFLSGDKVKPVLLNSKLPVDILGRVWELSDIDHDGML 180
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
D EF++A ++ L VP LPP+L+
Sbjct: 181 DRDEFAVAMFLVYCALEKEPVPMSLPPALV 210
Score = 81.0 bits (191), Expect = 3e-14
Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
Query: 339 TSPEVPMGVMSPPPMEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQS 398
TS + + S + W V K KY +F++ G SG + + ++L S+LP
Sbjct: 106 TSSPLLISGTSAAELPWAVKPEDKAKYDAIFDSLSPVN-GFLSGDKVKPVLLNSKLPVDI 164
Query: 399 LAQIWALADLDADGKLGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L ++W L+D+D DG L +EF +AM+L A + EPVP LPP L+PP
Sbjct: 165 LGRVWELSDIDHDGMLDRDEFAVAMFLVYCALEKEPVPMSLPPALVPP 212
Score = 72.1 bits (169), Expect = 1e-11
Identities = 40/106 (37%), Positives = 58/106 (54%), Gaps = 2/106 (1%)
Query: 343 VPMGVMSPPPME-WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQ 401
+P ++ P + W V +K KY ++F TD+ G SG + R I L++ LP LA
Sbjct: 205 LPPALVPPSKRKTWVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAH 264
Query: 402 IWALADLDADGKLGCEEFVLAMYL-CEKATQGEPVPARLPPELIPP 446
IW+L D GKL ++F LA +L +K +G P L PE+IPP
Sbjct: 265 IWSLCDTKDCGKLSKDQFALAFHLISQKLIKGIDPPHVLTPEMIPP 310
Score = 60.5 bits (140), Expect = 4e-08
Identities = 31/91 (34%), Positives = 52/91 (57%), Gaps = 2/91 (2%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + E AK+ E F ++G ++G + + L++ LP +L IWSL DT GKL
Sbjct: 218 WVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAHIWSLCDTKDCGKL 277
Query: 65 DLKEFSIACKIINLKL-RGLEVPKMLPPSLI 94
+F++A +I+ KL +G++ P +L P +I
Sbjct: 278 SKDQFALAFHLISQKLIKGIDPPHVLTPEMI 308
Score = 52.0 bits (119), Expect = 1e-05
Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 16 FSEHFRNLGPVN-GNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLDLKEFSIACK 74
+ +++R + N G + A F+ +S LP +LG+IW LADT+ G L+ +EF +A +
Sbjct: 19 YEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALR 78
Query: 75 IINLKLRGLEV 85
++ GLEV
Sbjct: 79 LVACAQNGLEV 89
Score = 44.8 bits (101), Expect = 0.002
Identities = 26/82 (31%), Positives = 37/82 (45%)
Query: 365 YTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLGCEEFVLAMY 424
Y + + D TG + A + + +S LP L +IW LAD D G L +EF +A+
Sbjct: 19 YEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALR 78
Query: 425 LCEKATQGEPVPARLPPELIPP 446
L A G V +PP
Sbjct: 79 LVACAQNGLEVSLSSLNLAVPP 100
>AL671986-11|CAI13030.1| 896|Homo sapiens epidermal growth factor
receptor pathway substrate 15 protein.
Length = 896
Score = 83.8 bits (198), Expect = 4e-15
Identities = 36/90 (40%), Positives = 57/90 (63%)
Query: 5 PWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
PW ++ + AK+ F +L PVNG L+G++ K +L S+LP +LG++W L+D + DG L
Sbjct: 121 PWAVKPEDKAKYDAIFDSLSPVNGFLSGDKVKPVLLNSKLPVDILGRVWELSDIDHDGML 180
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
D EF++A ++ L VP LPP+L+
Sbjct: 181 DRDEFAVAMFLVYCALEKEPVPMSLPPALV 210
Score = 81.0 bits (191), Expect = 3e-14
Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
Query: 339 TSPEVPMGVMSPPPMEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQS 398
TS + + S + W V K KY +F++ G SG + + ++L S+LP
Sbjct: 106 TSSPLLISGTSAAELPWAVKPEDKAKYDAIFDSLSPVN-GFLSGDKVKPVLLNSKLPVDI 164
Query: 399 LAQIWALADLDADGKLGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L ++W L+D+D DG L +EF +AM+L A + EPVP LPP L+PP
Sbjct: 165 LGRVWELSDIDHDGMLDRDEFAVAMFLVYCALEKEPVPMSLPPALVPP 212
Score = 72.1 bits (169), Expect = 1e-11
Identities = 40/106 (37%), Positives = 58/106 (54%), Gaps = 2/106 (1%)
Query: 343 VPMGVMSPPPME-WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQ 401
+P ++ P + W V +K KY ++F TD+ G SG + R I L++ LP LA
Sbjct: 205 LPPALVPPSKRKTWVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAH 264
Query: 402 IWALADLDADGKLGCEEFVLAMYL-CEKATQGEPVPARLPPELIPP 446
IW+L D GKL ++F LA +L +K +G P L PE+IPP
Sbjct: 265 IWSLCDTKDCGKLSKDQFALAFHLISQKLIKGIDPPHVLTPEMIPP 310
Score = 60.5 bits (140), Expect = 4e-08
Identities = 31/91 (34%), Positives = 52/91 (57%), Gaps = 2/91 (2%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + E AK+ E F ++G ++G + + L++ LP +L IWSL DT GKL
Sbjct: 218 WVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAHIWSLCDTKDCGKL 277
Query: 65 DLKEFSIACKIINLKL-RGLEVPKMLPPSLI 94
+F++A +I+ KL +G++ P +L P +I
Sbjct: 278 SKDQFALAFHLISQKLIKGIDPPHVLTPEMI 308
Score = 52.0 bits (119), Expect = 1e-05
Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 16 FSEHFRNLGPVN-GNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLDLKEFSIACK 74
+ +++R + N G + A F+ +S LP +LG+IW LADT+ G L+ +EF +A +
Sbjct: 19 YEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALR 78
Query: 75 IINLKLRGLEV 85
++ GLEV
Sbjct: 79 LVACAQNGLEV 89
Score = 44.8 bits (101), Expect = 0.002
Identities = 26/82 (31%), Positives = 37/82 (45%)
Query: 365 YTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLGCEEFVLAMY 424
Y + + D TG + A + + +S LP L +IW LAD D G L +EF +A+
Sbjct: 19 YEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALR 78
Query: 425 LCEKATQGEPVPARLPPELIPP 446
L A G V +PP
Sbjct: 79 LVACAQNGLEVSLSSLNLAVPP 100
>AL671986-10|CAI13031.1| 762|Homo sapiens epidermal growth factor
receptor pathway substrate 15 protein.
Length = 762
Score = 83.8 bits (198), Expect = 4e-15
Identities = 36/90 (40%), Positives = 57/90 (63%)
Query: 5 PWTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
PW ++ + AK+ F +L PVNG L+G++ K +L S+LP +LG++W L+D + DG L
Sbjct: 121 PWAVKPEDKAKYDAIFDSLSPVNGFLSGDKVKPVLLNSKLPVDILGRVWELSDIDHDGML 180
Query: 65 DLKEFSIACKIINLKLRGLEVPKMLPPSLI 94
D EF++A ++ L VP LPP+L+
Sbjct: 181 DRDEFAVAMFLVYCALEKEPVPMSLPPALV 210
Score = 81.0 bits (191), Expect = 3e-14
Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
Query: 339 TSPEVPMGVMSPPPMEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQS 398
TS + + S + W V K KY +F++ G SG + + ++L S+LP
Sbjct: 106 TSSPLLISGTSAAELPWAVKPEDKAKYDAIFDSLSPVN-GFLSGDKVKPVLLNSKLPVDI 164
Query: 399 LAQIWALADLDADGKLGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L ++W L+D+D DG L +EF +AM+L A + EPVP LPP L+PP
Sbjct: 165 LGRVWELSDIDHDGMLDRDEFAVAMFLVYCALEKEPVPMSLPPALVPP 212
Score = 72.1 bits (169), Expect = 1e-11
Identities = 40/106 (37%), Positives = 58/106 (54%), Gaps = 2/106 (1%)
Query: 343 VPMGVMSPPPME-WGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQ 401
+P ++ P + W V +K KY ++F TD+ G SG + R I L++ LP LA
Sbjct: 205 LPPALVPPSKRKTWVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAH 264
Query: 402 IWALADLDADGKLGCEEFVLAMYL-CEKATQGEPVPARLPPELIPP 446
IW+L D GKL ++F LA +L +K +G P L PE+IPP
Sbjct: 265 IWSLCDTKDCGKLSKDQFALAFHLISQKLIKGIDPPHVLTPEMIPP 310
Score = 60.5 bits (140), Expect = 4e-08
Identities = 31/91 (34%), Positives = 52/91 (57%), Gaps = 2/91 (2%)
Query: 6 WTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKL 64
W + E AK+ E F ++G ++G + + L++ LP +L IWSL DT GKL
Sbjct: 218 WVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAHIWSLCDTKDCGKL 277
Query: 65 DLKEFSIACKIINLKL-RGLEVPKMLPPSLI 94
+F++A +I+ KL +G++ P +L P +I
Sbjct: 278 SKDQFALAFHLISQKLIKGIDPPHVLTPEMI 308
Score = 52.0 bits (119), Expect = 1e-05
Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 16 FSEHFRNLGPVN-GNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLDLKEFSIACK 74
+ +++R + N G + A F+ +S LP +LG+IW LADT+ G L+ +EF +A +
Sbjct: 19 YEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALR 78
Query: 75 IINLKLRGLEV 85
++ GLEV
Sbjct: 79 LVACAQNGLEV 89
Score = 44.8 bits (101), Expect = 0.002
Identities = 26/82 (31%), Positives = 37/82 (45%)
Query: 365 YTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLGCEEFVLAMY 424
Y + + D TG + A + + +S LP L +IW LAD D G L +EF +A+
Sbjct: 19 YEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALR 78
Query: 425 LCEKATQGEPVPARLPPELIPP 446
L A G V +PP
Sbjct: 79 LVACAQNGLEVSLSSLNLAVPP 100
>AF214736-1|AAF32285.1| 535|Homo sapiens EH domain containing
protein 2 protein.
Length = 535
Score = 82.6 bits (195), Expect = 8e-15
Identities = 40/89 (44%), Positives = 57/89 (64%), Gaps = 1/89 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLD 65
W + A + + E F L PV+G +TG AK+ M++S+LP VLG+IW LAD + DG LD
Sbjct: 439 WVV-ARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSVLGKIWKLADIDKDGMLD 497
Query: 66 LKEFSIACKIINLKLRGLEVPKMLPPSLI 94
EF++A +I +KL G E+P LP L+
Sbjct: 498 DDEFALANHLIKVKLEGHELPNELPAHLL 526
Score = 66.5 bits (155), Expect = 6e-10
Identities = 34/93 (36%), Positives = 52/93 (55%), Gaps = 2/93 (2%)
Query: 354 EWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGK 413
EW V + + + Y ++F G +G A+ M++S+LP L +IW LAD+D DG
Sbjct: 438 EWVVARDKPM-YDEIFYTLSPVD-GKITGANAKKEMVRSKLPNSVLGKIWKLADIDKDGM 495
Query: 414 LGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L +EF LA +L + +G +P LP L+PP
Sbjct: 496 LDDDEFALANHLIKVKLEGHELPNELPAHLLPP 528
>AF181264-1|AAF40471.1| 546|Homo sapiens EH domain containing 3
protein.
Length = 546
Score = 82.6 bits (195), Expect = 8e-15
Identities = 40/89 (44%), Positives = 57/89 (64%), Gaps = 1/89 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLD 65
W + A + + E F L PV+G +TG AK+ M++S+LP VLG+IW LAD + DG LD
Sbjct: 439 WVV-ARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSVLGKIWKLADIDKDGMLD 497
Query: 66 LKEFSIACKIINLKLRGLEVPKMLPPSLI 94
EF++A +I +KL G E+P LP L+
Sbjct: 498 DDEFALANHLIKVKLEGHELPNELPAHLL 526
Score = 63.7 bits (148), Expect = 4e-09
Identities = 33/92 (35%), Positives = 51/92 (55%), Gaps = 2/92 (2%)
Query: 354 EWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGK 413
EW V + + + Y ++F G +G A+ M++S+LP L +IW LAD+D DG
Sbjct: 438 EWVVARDKPM-YDEIFYTLSPVD-GKITGANAKKEMVRSKLPNSVLGKIWKLADIDKDGM 495
Query: 414 LGCEEFVLAMYLCEKATQGEPVPARLPPELIP 445
L +EF LA +L + +G +P LP L+P
Sbjct: 496 LDDDEFALANHLIKVKLEGHELPNELPAHLLP 527
>AF099011-1|AAD45866.1| 534|Homo sapiens EH-domain containing
protein testilin protein.
Length = 534
Score = 82.6 bits (195), Expect = 8e-15
Identities = 39/89 (43%), Positives = 56/89 (62%), Gaps = 1/89 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLD 65
W + + + E F L PVNG +TG K+ M++S+LP LG+IW LAD + DG LD
Sbjct: 439 WVV-GKDKPSYDEIFYTLSPVNGKITGANVKKEMVKSKLPNTELGKIWKLADVDKDGLLD 497
Query: 66 LKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF++A +I +KL G E+P LPP L+
Sbjct: 498 DEEFALANHLIKVKLEGHELPADLPPHLV 526
Score = 71.7 bits (168), Expect = 2e-11
Identities = 37/94 (39%), Positives = 53/94 (56%), Gaps = 2/94 (2%)
Query: 353 MEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADG 412
+EW V + K Y ++F G +G + M++S+LP L +IW LAD+D DG
Sbjct: 437 VEWVVGK-DKPSYDEIFYTLSPVN-GKITGANVKKEMVKSKLPNTELGKIWKLADVDKDG 494
Query: 413 KLGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L EEF LA +L + +G +PA LPP L+PP
Sbjct: 495 LLDDEEFALANHLIKVKLEGHELPADLPPHLVPP 528
>BC014445-1|AAH14445.1| 543|Homo sapiens EH-domain containing 2
protein.
Length = 543
Score = 79.4 bits (187), Expect = 8e-14
Identities = 37/89 (41%), Positives = 57/89 (64%), Gaps = 1/89 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLD 65
W + + +K+ E F NL P +G L+G +AK +M+ ++LP VLG+IW L+D + DG LD
Sbjct: 444 WVV-TKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLD 502
Query: 66 LKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF++A +I KL G +P LP L+
Sbjct: 503 DEEFALASHLIEAKLEGHGLPANLPRRLV 531
Score = 73.3 bits (172), Expect = 5e-12
Identities = 39/93 (41%), Positives = 56/93 (60%), Gaps = 2/93 (2%)
Query: 354 EWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGK 413
EW V + K KY ++F A G SG++A++ M+ ++LP L +IW L+D+D DG
Sbjct: 443 EWVVTK-DKSKYDEIFYNLAPAD-GKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGM 500
Query: 414 LGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L EEF LA +L E +G +PA LP L+PP
Sbjct: 501 LDDEEFALASHLIEAKLEGHGLPANLPRRLVPP 533
>AF454952-1|AAL51078.1| 543|Homo sapiens EH domain-containing
protein-2 protein.
Length = 543
Score = 79.4 bits (187), Expect = 8e-14
Identities = 37/89 (41%), Positives = 57/89 (64%), Gaps = 1/89 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLD 65
W + + +K+ E F NL P +G L+G +AK +M+ ++LP VLG+IW L+D + DG LD
Sbjct: 444 WVV-TKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLD 502
Query: 66 LKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF++A +I KL G +P LP L+
Sbjct: 503 DEEFALASHLIEAKLEGHGLPANLPRRLV 531
Score = 73.3 bits (172), Expect = 5e-12
Identities = 39/93 (41%), Positives = 56/93 (60%), Gaps = 2/93 (2%)
Query: 354 EWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGK 413
EW V + K KY ++F A G SG++A++ M+ ++LP L +IW L+D+D DG
Sbjct: 443 EWVVTK-DKSKYDEIFYNLAPAD-GKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGM 500
Query: 414 LGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L EEF LA +L E +G +PA LP L+PP
Sbjct: 501 LDDEEFALASHLIEAKLEGHGLPANLPRRLVPP 533
>AF181263-1|AAF40470.1| 543|Homo sapiens EH domain containing 2
protein.
Length = 543
Score = 79.4 bits (187), Expect = 8e-14
Identities = 37/89 (41%), Positives = 57/89 (64%), Gaps = 1/89 (1%)
Query: 6 WTIQAHEHAKFSEHFRNLGPVNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLD 65
W + + +K+ E F NL P +G L+G +AK +M+ ++LP VLG+IW L+D + DG LD
Sbjct: 444 WVV-TKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLD 502
Query: 66 LKEFSIACKIINLKLRGLEVPKMLPPSLI 94
+EF++A +I KL G +P LP L+
Sbjct: 503 DEEFALASHLIEAKLEGHGLPANLPRRLV 531
Score = 73.3 bits (172), Expect = 5e-12
Identities = 39/93 (41%), Positives = 56/93 (60%), Gaps = 2/93 (2%)
Query: 354 EWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGK 413
EW V + K KY ++F A G SG++A++ M+ ++LP L +IW L+D+D DG
Sbjct: 443 EWVVTK-DKSKYDEIFYNLAPAD-GKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGM 500
Query: 414 LGCEEFVLAMYLCEKATQGEPVPARLPPELIPP 446
L EEF LA +L E +G +PA LP L+PP
Sbjct: 501 LDDEEFALASHLIEAKLEGHGLPANLPRRLVPP 533
>BC108893-1|AAI08894.1| 728|Homo sapiens SH3D19 protein protein.
Length = 728
Score = 75.8 bits (178), Expect = 1e-12
Identities = 54/153 (35%), Positives = 76/153 (49%), Gaps = 19/153 (12%)
Query: 1147 DSGRDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNR 1206
DSG +S E +AL S+TA + + LS +G + + ++ DS W G LQ +R
Sbjct: 589 DSGSNSQVNSLPAEWCEALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQ----DR 644
Query: 1207 QVGWFPASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+ G FPA +V R P + M A+ + K ALY + +N DELSF+
Sbjct: 645 E-GIFPAVFV-----------RPCPAEAKSMLAIVPKG--RKAKALYDFRGENEDELSFK 690
Query: 1267 KDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
DII + S D W GEL G G+FP NY+
Sbjct: 691 AGDIITELE-SVDDDWMSGELMGKSGIFPKNYI 722
Score = 66.1 bits (154), Expect = 8e-10
Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 14/141 (9%)
Query: 1159 HEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKV 1218
H +V L + A + L+L G+++ + +K D+ W+ G RN Q+G FPA+YVKV
Sbjct: 437 HAVV--LHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNC----RN-QIGIFPANYVKV 489
Query: 1219 LQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+ +SS + VA + Y + DELSF + +II + +
Sbjct: 490 IIDIPEGGNGKRECVSSHC------VKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVN 543
Query: 1279 DPAWWQGELRGMVGLFPSNYV 1299
+ W +GE+RG G+FP N+V
Sbjct: 544 EE-WARGEVRGRTGIFPLNFV 563
Score = 49.2 bits (112), Expect = 1e-04
Identities = 44/168 (26%), Positives = 73/168 (43%), Gaps = 30/168 (17%)
Query: 888 RCV--YPFVGRSADELSVQPGDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESYVEDLNAP 945
RCV + ++G DELS G++I+ RG++G FP ++VE +
Sbjct: 513 RCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEV---RGRTGIFPLNFVEPVEDY 569
Query: 946 TAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYI 1005
V+ T P + E ++ +LPA E+
Sbjct: 570 PTSGANVLSTKVP------LKTKKEDSGSNSQVNSLPA------------------EWCE 605
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
A + +++ DL F+ G+RI+++ R D DW GR+ R GIFP+ +V
Sbjct: 606 ALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQDREGIFPAVFV 653
Score = 47.2 bits (107), Expect = 4e-04
Identities = 31/126 (24%), Positives = 64/126 (50%), Gaps = 8/126 (6%)
Query: 1179 MKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRTTPVLSSKMD 1238
M+G +LV+ K+ ++ + E + KG + G S +K++ R+ P S
Sbjct: 375 MRGDVLVMLKQTENNYLECQ---KGED--TGRVHLSQMKIITPLDEHL-RSRPNDPSHAQ 428
Query: 1239 ALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNY 1298
P ++ V L+ + A+ D+L+ +I+ + ++ D W++G R +G+FP+NY
Sbjct: 429 K-PVDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKI-DTDWYRGNCRNQIGIFPANY 486
Query: 1299 VTKLVN 1304
V +++
Sbjct: 487 VKVIID 492
Score = 41.1 bits (92), Expect = 0.025
Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 976 DLGGALPAV-VDPGRTVSEPV-SVEDDGEFYIASYPYSSSEPGDLVFEAGERI-EVVRRD 1032
D G PAV V P ++ + ++ G A Y + +L F+AG+ I E+ D
Sbjct: 643 DREGIFPAVFVRPCPAEAKSMLAIVPKGRKAKALYDFRGENEDELSFKAGDIITELESVD 702
Query: 1033 GDWWTGRIGARTGIFPSNYV 1052
DW +G + ++GIFP NY+
Sbjct: 703 DDWMSGELMGKSGIFPKNYI 722
Score = 35.5 bits (78), Expect = 1.3
Identities = 16/57 (28%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 997 VEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
V+ + + + + + DL +GE + ++ + D DW+ G + GIFP+NYV
Sbjct: 431 VDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCRNQIGIFPANYV 487
Score = 35.5 bits (78), Expect = 1.3
Identities = 30/121 (24%), Positives = 51/121 (42%), Gaps = 3/121 (2%)
Query: 934 FPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSE 993
FP V+DLN + + ++E ++ G ++ + + + G E
Sbjct: 444 FPAEQVDDLNLTSGEIVYLLEKIDTDWY-RGNCRNQIGIFPANYVKVIIDIPEGGNGKRE 502
Query: 994 PVSVED-DGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNY 1051
VS G +A + Y + +L F GE I + + +W G + RTGIFP N+
Sbjct: 503 CVSSHCVKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGRTGIFPLNF 562
Query: 1052 V 1052
V
Sbjct: 563 V 563
>BC108892-1|AAI08893.1| 764|Homo sapiens SH3D19 protein protein.
Length = 764
Score = 75.8 bits (178), Expect = 1e-12
Identities = 54/153 (35%), Positives = 76/153 (49%), Gaps = 19/153 (12%)
Query: 1147 DSGRDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNR 1206
DSG +S E +AL S+TA + + LS +G + + ++ DS W G LQ +R
Sbjct: 625 DSGSNSQVNSLPAEWCEALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQ----DR 680
Query: 1207 QVGWFPASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+ G FPA +V R P + M A+ + K ALY + +N DELSF+
Sbjct: 681 E-GIFPAVFV-----------RPCPAEAKSMLAIVPKG--RKAKALYDFRGENEDELSFK 726
Query: 1267 KDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
DII + S D W GEL G G+FP NY+
Sbjct: 727 AGDIITELE-SVDDDWMSGELMGKSGIFPKNYI 758
Score = 66.1 bits (154), Expect = 8e-10
Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 14/141 (9%)
Query: 1159 HEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKV 1218
H +V L + A + L+L G+++ + +K D+ W+ G RN Q+G FPA+YVKV
Sbjct: 473 HAVV--LHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNC----RN-QIGIFPANYVKV 525
Query: 1219 LQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+ +SS + VA + Y + DELSF + +II + +
Sbjct: 526 IIDIPEGGNGKRECVSSHC------VKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVN 579
Query: 1279 DPAWWQGELRGMVGLFPSNYV 1299
+ W +GE+RG G+FP N+V
Sbjct: 580 EE-WARGEVRGRTGIFPLNFV 599
Score = 49.2 bits (112), Expect = 1e-04
Identities = 44/168 (26%), Positives = 73/168 (43%), Gaps = 30/168 (17%)
Query: 888 RCV--YPFVGRSADELSVQPGDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESYVEDLNAP 945
RCV + ++G DELS G++I+ RG++G FP ++VE +
Sbjct: 549 RCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEV---RGRTGIFPLNFVEPVEDY 605
Query: 946 TAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYI 1005
V+ T P + E ++ +LPA E+
Sbjct: 606 PTSGANVLSTKVP------LKTKKEDSGSNSQVNSLPA------------------EWCE 641
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
A + +++ DL F+ G+RI+++ R D DW GR+ R GIFP+ +V
Sbjct: 642 ALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQDREGIFPAVFV 689
Score = 47.2 bits (107), Expect = 4e-04
Identities = 31/126 (24%), Positives = 64/126 (50%), Gaps = 8/126 (6%)
Query: 1179 MKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRTTPVLSSKMD 1238
M+G +LV+ K+ ++ + E + KG + G S +K++ R+ P S
Sbjct: 411 MRGDVLVMLKQTENNYLECQ---KGED--TGRVHLSQMKIITPLDEHL-RSRPNDPSHAQ 464
Query: 1239 ALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNY 1298
P ++ V L+ + A+ D+L+ +I+ + ++ D W++G R +G+FP+NY
Sbjct: 465 K-PVDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKI-DTDWYRGNCRNQIGIFPANY 522
Query: 1299 VTKLVN 1304
V +++
Sbjct: 523 VKVIID 528
Score = 41.1 bits (92), Expect = 0.025
Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 976 DLGGALPAV-VDPGRTVSEPV-SVEDDGEFYIASYPYSSSEPGDLVFEAGERI-EVVRRD 1032
D G PAV V P ++ + ++ G A Y + +L F+AG+ I E+ D
Sbjct: 679 DREGIFPAVFVRPCPAEAKSMLAIVPKGRKAKALYDFRGENEDELSFKAGDIITELESVD 738
Query: 1033 GDWWTGRIGARTGIFPSNYV 1052
DW +G + ++GIFP NY+
Sbjct: 739 DDWMSGELMGKSGIFPKNYI 758
Score = 35.5 bits (78), Expect = 1.3
Identities = 16/57 (28%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 997 VEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
V+ + + + + + DL +GE + ++ + D DW+ G + GIFP+NYV
Sbjct: 467 VDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCRNQIGIFPANYV 523
Score = 35.5 bits (78), Expect = 1.3
Identities = 30/121 (24%), Positives = 51/121 (42%), Gaps = 3/121 (2%)
Query: 934 FPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSE 993
FP V+DLN + + ++E ++ G ++ + + + G E
Sbjct: 480 FPAEQVDDLNLTSGEIVYLLEKIDTDWY-RGNCRNQIGIFPANYVKVIIDIPEGGNGKRE 538
Query: 994 PVSVED-DGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNY 1051
VS G +A + Y + +L F GE I + + +W G + RTGIFP N+
Sbjct: 539 CVSSHCVKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGRTGIFPLNF 598
Query: 1052 V 1052
V
Sbjct: 599 V 599
>BC108891-1|AAI08892.1| 764|Homo sapiens SH3D19 protein protein.
Length = 764
Score = 75.8 bits (178), Expect = 1e-12
Identities = 54/153 (35%), Positives = 76/153 (49%), Gaps = 19/153 (12%)
Query: 1147 DSGRDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNR 1206
DSG +S E +AL S+TA + + LS +G + + ++ DS W G LQ +R
Sbjct: 625 DSGSNSQVNSLPAEWCEALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQ----DR 680
Query: 1207 QVGWFPASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+ G FPA +V R P + M A+ + K ALY + +N DELSF+
Sbjct: 681 E-GIFPAVFV-----------RPCPAEAKSMLAIVPKG--RKAKALYDFRGENEDELSFK 726
Query: 1267 KDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
DII + S D W GEL G G+FP NY+
Sbjct: 727 AGDIITELE-SVDDDWMSGELMGKSGIFPKNYI 758
Score = 66.1 bits (154), Expect = 8e-10
Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 14/141 (9%)
Query: 1159 HEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKV 1218
H +V L + A + L+L G+++ + +K D+ W+ G RN Q+G FPA+YVKV
Sbjct: 473 HAVV--LHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNC----RN-QIGIFPANYVKV 525
Query: 1219 LQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+ +SS + VA + Y + DELSF + +II + +
Sbjct: 526 IIDIPEGGNGKRECVSSHC------VKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVN 579
Query: 1279 DPAWWQGELRGMVGLFPSNYV 1299
+ W +GE+RG G+FP N+V
Sbjct: 580 EE-WARGEVRGRTGIFPLNFV 599
Score = 49.2 bits (112), Expect = 1e-04
Identities = 44/168 (26%), Positives = 73/168 (43%), Gaps = 30/168 (17%)
Query: 888 RCV--YPFVGRSADELSVQPGDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESYVEDLNAP 945
RCV + ++G DELS G++I+ RG++G FP ++VE +
Sbjct: 549 RCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEV---RGRTGIFPLNFVEPVEDY 605
Query: 946 TAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYI 1005
V+ T P + E ++ +LPA E+
Sbjct: 606 PTSGANVLSTKVP------LKTKKEDSGSNSQVNSLPA------------------EWCE 641
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
A + +++ DL F+ G+RI+++ R D DW GR+ R GIFP+ +V
Sbjct: 642 ALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQDREGIFPAVFV 689
Score = 47.2 bits (107), Expect = 4e-04
Identities = 31/126 (24%), Positives = 64/126 (50%), Gaps = 8/126 (6%)
Query: 1179 MKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRTTPVLSSKMD 1238
M+G +LV+ K+ ++ + E + KG + G S +K++ R+ P S
Sbjct: 411 MRGDVLVMLKQTENNYLECQ---KGED--TGRVHLSQMKIITPLDEHL-RSRPNDPSHAQ 464
Query: 1239 ALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNY 1298
P ++ V L+ + A+ D+L+ +I+ + ++ D W++G R +G+FP+NY
Sbjct: 465 K-PVDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKI-DTDWYRGNCRNQIGIFPANY 522
Query: 1299 VTKLVN 1304
V +++
Sbjct: 523 VKVIID 528
Score = 41.1 bits (92), Expect = 0.025
Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 976 DLGGALPAV-VDPGRTVSEPV-SVEDDGEFYIASYPYSSSEPGDLVFEAGERI-EVVRRD 1032
D G PAV V P ++ + ++ G A Y + +L F+AG+ I E+ D
Sbjct: 679 DREGIFPAVFVRPCPAEAKSMLAIVPKGRKAKALYDFRGENEDELSFKAGDIITELESVD 738
Query: 1033 GDWWTGRIGARTGIFPSNYV 1052
DW +G + ++GIFP NY+
Sbjct: 739 DDWMSGELMGKSGIFPKNYI 758
Score = 35.5 bits (78), Expect = 1.3
Identities = 16/57 (28%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 997 VEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
V+ + + + + + DL +GE + ++ + D DW+ G + GIFP+NYV
Sbjct: 467 VDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCRNQIGIFPANYV 523
Score = 35.5 bits (78), Expect = 1.3
Identities = 30/121 (24%), Positives = 51/121 (42%), Gaps = 3/121 (2%)
Query: 934 FPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSE 993
FP V+DLN + + ++E ++ G ++ + + + G E
Sbjct: 480 FPAEQVDDLNLTSGEIVYLLEKIDTDWY-RGNCRNQIGIFPANYVKVIIDIPEGGNGKRE 538
Query: 994 PVSVED-DGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNY 1051
VS G +A + Y + +L F GE I + + +W G + RTGIFP N+
Sbjct: 539 CVSSHCVKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGRTGIFPLNF 598
Query: 1052 V 1052
V
Sbjct: 599 V 599
>BC108890-1|AAI08891.1| 764|Homo sapiens SH3D19 protein protein.
Length = 764
Score = 75.8 bits (178), Expect = 1e-12
Identities = 54/153 (35%), Positives = 76/153 (49%), Gaps = 19/153 (12%)
Query: 1147 DSGRDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNR 1206
DSG +S E +AL S+TA + + LS +G + + ++ DS W G LQ +R
Sbjct: 625 DSGSNSQVNSLPAEWCEALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQ----DR 680
Query: 1207 QVGWFPASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+ G FPA +V R P + M A+ + K ALY + +N DELSF+
Sbjct: 681 E-GIFPAVFV-----------RPCPAEAKSMLAIVPKG--RKAKALYDFRGENEDELSFK 726
Query: 1267 KDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
DII + S D W GEL G G+FP NY+
Sbjct: 727 AGDIITELE-SVDDDWMSGELMGKSGIFPKNYI 758
Score = 66.1 bits (154), Expect = 8e-10
Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 14/141 (9%)
Query: 1159 HEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKV 1218
H +V L + A + L+L G+++ + +K D+ W+ G RN Q+G FPA+YVKV
Sbjct: 473 HAVV--LHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNC----RN-QIGIFPANYVKV 525
Query: 1219 LQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+ +SS + VA + Y + DELSF + +II + +
Sbjct: 526 IIDIPEGGNGKRECVSSHC------VKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVN 579
Query: 1279 DPAWWQGELRGMVGLFPSNYV 1299
+ W +GE+RG G+FP N+V
Sbjct: 580 EE-WARGEVRGRTGIFPLNFV 599
Score = 49.2 bits (112), Expect = 1e-04
Identities = 44/168 (26%), Positives = 73/168 (43%), Gaps = 30/168 (17%)
Query: 888 RCV--YPFVGRSADELSVQPGDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESYVEDLNAP 945
RCV + ++G DELS G++I+ RG++G FP ++VE +
Sbjct: 549 RCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEV---RGRTGIFPLNFVEPVEDY 605
Query: 946 TAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYI 1005
V+ T P + E ++ +LPA E+
Sbjct: 606 PTSGANVLSTKVP------LKTKKEDSGSNSQVNSLPA------------------EWCE 641
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
A + +++ DL F+ G+RI+++ R D DW GR+ R GIFP+ +V
Sbjct: 642 ALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQDREGIFPAVFV 689
Score = 47.2 bits (107), Expect = 4e-04
Identities = 31/126 (24%), Positives = 64/126 (50%), Gaps = 8/126 (6%)
Query: 1179 MKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRTTPVLSSKMD 1238
M+G +LV+ K+ ++ + E + KG + G S +K++ R+ P S
Sbjct: 411 MRGDVLVMLKQTENNYLECQ---KGED--TGRVHLSQMKIITPLDEHL-RSRPNDPSHAQ 464
Query: 1239 ALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNY 1298
P ++ V L+ + A+ D+L+ +I+ + ++ D W++G R +G+FP+NY
Sbjct: 465 K-PVDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKI-DTDWYRGNCRNQIGIFPANY 522
Query: 1299 VTKLVN 1304
V +++
Sbjct: 523 VKVIID 528
Score = 41.1 bits (92), Expect = 0.025
Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 976 DLGGALPAV-VDPGRTVSEPV-SVEDDGEFYIASYPYSSSEPGDLVFEAGERI-EVVRRD 1032
D G PAV V P ++ + ++ G A Y + +L F+AG+ I E+ D
Sbjct: 679 DREGIFPAVFVRPCPAEAKSMLAIVPKGRKAKALYDFRGENEDELSFKAGDIITELESVD 738
Query: 1033 GDWWTGRIGARTGIFPSNYV 1052
DW +G + ++GIFP NY+
Sbjct: 739 DDWMSGELMGKSGIFPKNYI 758
Score = 35.5 bits (78), Expect = 1.3
Identities = 16/57 (28%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 997 VEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
V+ + + + + + DL +GE + ++ + D DW+ G + GIFP+NYV
Sbjct: 467 VDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCRNQIGIFPANYV 523
Score = 35.5 bits (78), Expect = 1.3
Identities = 30/121 (24%), Positives = 51/121 (42%), Gaps = 3/121 (2%)
Query: 934 FPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSE 993
FP V+DLN + + ++E ++ G ++ + + + G E
Sbjct: 480 FPAEQVDDLNLTSGEIVYLLEKIDTDWY-RGNCRNQIGIFPANYVKVIIDIPEGGNGKRE 538
Query: 994 PVSVED-DGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNY 1051
VS G +A + Y + +L F GE I + + +W G + RTGIFP N+
Sbjct: 539 CVSSHCVKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGRTGIFPLNF 598
Query: 1052 V 1052
V
Sbjct: 599 V 599
>BC085613-1|AAH85613.1| 420|Homo sapiens SH3D19 protein protein.
Length = 420
Score = 75.8 bits (178), Expect = 1e-12
Identities = 54/153 (35%), Positives = 76/153 (49%), Gaps = 19/153 (12%)
Query: 1147 DSGRDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNR 1206
DSG +S E +AL S+TA + + LS +G + + ++ DS W G LQ +R
Sbjct: 281 DSGSNSQVNSLPAEWCEALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQ----DR 336
Query: 1207 QVGWFPASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+ G FPA +V R P + M A+ + K ALY + +N DELSF+
Sbjct: 337 E-GIFPAVFV-----------RPCPAEAKSMLAIVPKG--RKAKALYDFRGENEDELSFK 382
Query: 1267 KDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
DII + S D W GEL G G+FP NY+
Sbjct: 383 AGDIITELE-SVDDDWMSGELMGKSGIFPKNYI 414
Score = 66.1 bits (154), Expect = 8e-10
Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 14/141 (9%)
Query: 1159 HEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKV 1218
H +V L + A + L+L G+++ + +K D+ W+ G RN Q+G FPA+YVKV
Sbjct: 129 HAVV--LHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNC----RN-QIGIFPANYVKV 181
Query: 1219 LQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+ +SS + VA + Y + DELSF + +II + +
Sbjct: 182 IIDIPEGGNGKRECVSSHC------VKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVN 235
Query: 1279 DPAWWQGELRGMVGLFPSNYV 1299
+ W +GE+RG G+FP N+V
Sbjct: 236 EE-WARGEVRGRTGIFPLNFV 255
Score = 50.8 bits (116), Expect = 3e-05
Identities = 33/133 (24%), Positives = 68/133 (51%), Gaps = 8/133 (6%)
Query: 1172 SPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRTTP 1231
+P +LS +G +LV+ K+ ++ + E + KG + G S +K++ R+ P
Sbjct: 60 NPGELSCKRGDVLVMLKQTENNYLECQ---KGED--TGRVHLSQMKIITPLDEHL-RSRP 113
Query: 1232 VLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMV 1291
S P ++ V L+ + A+ D+L+ +I+ + ++ D W++G R +
Sbjct: 114 NDPSHAQK-PVDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKI-DTDWYRGNCRNQI 171
Query: 1292 GLFPSNYVTKLVN 1304
G+FP+NYV +++
Sbjct: 172 GIFPANYVKVIID 184
Score = 49.2 bits (112), Expect = 1e-04
Identities = 44/168 (26%), Positives = 73/168 (43%), Gaps = 30/168 (17%)
Query: 888 RCV--YPFVGRSADELSVQPGDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESYVEDLNAP 945
RCV + ++G DELS G++I+ RG++G FP ++VE +
Sbjct: 205 RCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEV---RGRTGIFPLNFVEPVEDY 261
Query: 946 TAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYI 1005
V+ T P + E ++ +LPA E+
Sbjct: 262 PTSGANVLSTKVP------LKTKKEDSGSNSQVNSLPA------------------EWCE 297
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
A + +++ DL F+ G+RI+++ R D DW GR+ R GIFP+ +V
Sbjct: 298 ALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQDREGIFPAVFV 345
Score = 41.1 bits (92), Expect = 0.025
Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 976 DLGGALPAV-VDPGRTVSEPV-SVEDDGEFYIASYPYSSSEPGDLVFEAGERI-EVVRRD 1032
D G PAV V P ++ + ++ G A Y + +L F+AG+ I E+ D
Sbjct: 335 DREGIFPAVFVRPCPAEAKSMLAIVPKGRKAKALYDFRGENEDELSFKAGDIITELESVD 394
Query: 1033 GDWWTGRIGARTGIFPSNYV 1052
DW +G + ++GIFP NY+
Sbjct: 395 DDWMSGELMGKSGIFPKNYI 414
Score = 35.5 bits (78), Expect = 1.3
Identities = 16/57 (28%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 997 VEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
V+ + + + + + DL +GE + ++ + D DW+ G + GIFP+NYV
Sbjct: 123 VDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCRNQIGIFPANYV 179
Score = 35.5 bits (78), Expect = 1.3
Identities = 30/121 (24%), Positives = 51/121 (42%), Gaps = 3/121 (2%)
Query: 934 FPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSE 993
FP V+DLN + + ++E ++ G ++ + + + G E
Sbjct: 136 FPAEQVDDLNLTSGEIVYLLEKIDTDWY-RGNCRNQIGIFPANYVKVIIDIPEGGNGKRE 194
Query: 994 PVSVED-DGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNY 1051
VS G +A + Y + +L F GE I + + +W G + RTGIFP N+
Sbjct: 195 CVSSHCVKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGRTGIFPLNF 254
Query: 1052 V 1052
V
Sbjct: 255 V 255
>BC045742-1|AAH45742.1| 208|Homo sapiens SH3D19 protein protein.
Length = 208
Score = 75.8 bits (178), Expect = 1e-12
Identities = 54/153 (35%), Positives = 76/153 (49%), Gaps = 19/153 (12%)
Query: 1147 DSGRDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNR 1206
DSG +S E +AL S+TA + + LS +G + + ++ DS W G LQ +R
Sbjct: 69 DSGSNSQVNSLPAEWCEALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQ----DR 124
Query: 1207 QVGWFPASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+ G FPA +V R P + M A+ + K ALY + +N DELSF+
Sbjct: 125 E-GIFPAVFV-----------RPCPAEAKSMLAIVPKG--RKAKALYDFRGENEDELSFK 170
Query: 1267 KDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
DII + S D W GEL G G+FP NY+
Sbjct: 171 AGDIITELE-SVDDDWMSGELMGKSGIFPKNYI 202
Score = 45.2 bits (102), Expect = 0.002
Identities = 41/160 (25%), Positives = 68/160 (42%), Gaps = 28/160 (17%)
Query: 894 VGRSADELSVQPGDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESYVEDLNAPTAFVTEVI 953
+G DELS G++I+ RG++G FP ++VE + V+
Sbjct: 1 IGEQKDELSFSEGEIIILKEYVNEEWARGEV---RGRTGIFPLNFVEPVEDYPTSGANVL 57
Query: 954 ETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSS 1013
T P + E ++ +LPA E+ A + +++
Sbjct: 58 STKVP------LKTKKEDSGSNSQVNSLPA------------------EWCEALHSFTAE 93
Query: 1014 EPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
DL F+ G+RI+++ R D DW GR+ R GIFP+ +V
Sbjct: 94 TSDDLSFKRGDRIQILERLDSDWCRGRLQDREGIFPAVFV 133
Score = 41.1 bits (92), Expect = 0.025
Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 976 DLGGALPAV-VDPGRTVSEPV-SVEDDGEFYIASYPYSSSEPGDLVFEAGERI-EVVRRD 1032
D G PAV V P ++ + ++ G A Y + +L F+AG+ I E+ D
Sbjct: 123 DREGIFPAVFVRPCPAEAKSMLAIVPKGRKAKALYDFRGENEDELSFKAGDIITELESVD 182
Query: 1033 GDWWTGRIGARTGIFPSNYV 1052
DW +G + ++GIFP NY+
Sbjct: 183 DDWMSGELMGKSGIFPKNYI 202
Score = 38.7 bits (86), Expect = 0.14
Identities = 17/42 (40%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
Query: 1258 QNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+ DELSF + +II + + + W +GE+RG G+FP N+V
Sbjct: 3 EQKDELSFSEGEIIILKEYVNEE-WARGEVRGRTGIFPLNFV 43
>AL133047-1|CAB61374.1| 408|Homo sapiens hypothetical protein
protein.
Length = 408
Score = 75.8 bits (178), Expect = 1e-12
Identities = 54/153 (35%), Positives = 76/153 (49%), Gaps = 19/153 (12%)
Query: 1147 DSGRDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNR 1206
DSG +S E +AL S+TA + + LS +G + + ++ DS W G LQ +R
Sbjct: 269 DSGSNSQVNSLPAEWCEALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQ----DR 324
Query: 1207 QVGWFPASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+ G FPA +V R P + M A+ + K ALY + +N DELSF+
Sbjct: 325 E-GIFPAVFV-----------RPCPAEAKSMLAIVPKG--RKAKALYDFRGENEDELSFK 370
Query: 1267 KDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
DII + S D W GEL G G+FP NY+
Sbjct: 371 AGDIITELE-SVDDDWMSGELMGKSGIFPKNYI 402
Score = 66.1 bits (154), Expect = 8e-10
Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 14/141 (9%)
Query: 1159 HEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKV 1218
H +V L + A + L+L G+++ + +K D+ W+ G RN Q+G FPA+YVKV
Sbjct: 117 HAVV--LHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNC----RN-QIGIFPANYVKV 169
Query: 1219 LQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+ +SS + VA + Y + DELSF + +II + +
Sbjct: 170 IIDIPEGGNGKRECVSSHC------VKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVN 223
Query: 1279 DPAWWQGELRGMVGLFPSNYV 1299
+ W +GE+RG G+FP N+V
Sbjct: 224 EE-WARGEVRGRTGIFPLNFV 243
Score = 50.8 bits (116), Expect = 3e-05
Identities = 33/133 (24%), Positives = 68/133 (51%), Gaps = 8/133 (6%)
Query: 1172 SPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRTTP 1231
+P +LS +G +LV+ K+ ++ + E + KG + G S +K++ R+ P
Sbjct: 48 NPGELSCKRGDVLVMLKQTENNYLECQ---KGED--TGRVHLSQMKIITPLDEHL-RSRP 101
Query: 1232 VLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMV 1291
S P ++ V L+ + A+ D+L+ +I+ + ++ D W++G R +
Sbjct: 102 NDPSHAQK-PVDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKI-DTDWYRGNCRNQI 159
Query: 1292 GLFPSNYVTKLVN 1304
G+FP+NYV +++
Sbjct: 160 GIFPANYVKVIID 172
Score = 49.2 bits (112), Expect = 1e-04
Identities = 44/168 (26%), Positives = 73/168 (43%), Gaps = 30/168 (17%)
Query: 888 RCV--YPFVGRSADELSVQPGDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESYVEDLNAP 945
RCV + ++G DELS G++I+ RG++G FP ++VE +
Sbjct: 193 RCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEV---RGRTGIFPLNFVEPVEDY 249
Query: 946 TAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYI 1005
V+ T P + E ++ +LPA E+
Sbjct: 250 PTSGANVLSTKVP------LKTKKEDSGSNSQVNSLPA------------------EWCE 285
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
A + +++ DL F+ G+RI+++ R D DW GR+ R GIFP+ +V
Sbjct: 286 ALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQDREGIFPAVFV 333
Score = 41.1 bits (92), Expect = 0.025
Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 976 DLGGALPAV-VDPGRTVSEPV-SVEDDGEFYIASYPYSSSEPGDLVFEAGERI-EVVRRD 1032
D G PAV V P ++ + ++ G A Y + +L F+AG+ I E+ D
Sbjct: 323 DREGIFPAVFVRPCPAEAKSMLAIVPKGRKAKALYDFRGENEDELSFKAGDIITELESVD 382
Query: 1033 GDWWTGRIGARTGIFPSNYV 1052
DW +G + ++GIFP NY+
Sbjct: 383 DDWMSGELMGKSGIFPKNYI 402
Score = 35.5 bits (78), Expect = 1.3
Identities = 16/57 (28%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 997 VEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
V+ + + + + + DL +GE + ++ + D DW+ G + GIFP+NYV
Sbjct: 111 VDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCRNQIGIFPANYV 167
Score = 35.5 bits (78), Expect = 1.3
Identities = 30/121 (24%), Positives = 51/121 (42%), Gaps = 3/121 (2%)
Query: 934 FPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSE 993
FP V+DLN + + ++E ++ G ++ + + + G E
Sbjct: 124 FPAEQVDDLNLTSGEIVYLLEKIDTDWY-RGNCRNQIGIFPANYVKVIIDIPEGGNGKRE 182
Query: 994 PVSVED-DGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNY 1051
VS G +A + Y + +L F GE I + + +W G + RTGIFP N+
Sbjct: 183 CVSSHCVKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGRTGIFPLNF 242
Query: 1052 V 1052
V
Sbjct: 243 V 243
>AL591845-2|CAH71860.2| 378|Homo sapiens chromosome 1 open reading
frame 113 protein.
Length = 378
Score = 72.5 bits (170), Expect = 9e-12
Identities = 46/150 (30%), Positives = 80/150 (53%), Gaps = 22/150 (14%)
Query: 1167 SYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTS 1226
SY+ ++L L G+++ + K+ + GWW G+ +N Q+G FP+++V++L S +
Sbjct: 93 SYSPEQADELKLQAGEIVEMIKEIEDGWWLGK-----KNGQLGAFPSNFVELLDSGPPSL 147
Query: 1227 G-----------RTTPVLSS-KMDALPT--ETVIDKVV--ALYPYTAQNADELSFEKDDI 1270
G + P LSS D+ P +TV V L+ Y + DEL+ + D+
Sbjct: 148 GNPDMPSVSPGPQRPPKLSSLAYDSPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDV 207
Query: 1271 IAVTDRS-QDPAWWQGELRGMVGLFPSNYV 1299
+ V ++ +D WW+GE +G G+FP N+V
Sbjct: 208 VKVLSKTTEDKGWWEGECQGRRGVFPDNFV 237
Score = 57.2 bits (132), Expect = 4e-07
Identities = 41/144 (28%), Positives = 64/144 (44%), Gaps = 9/144 (6%)
Query: 1162 VQALASYTATSPEQLSLMKGQLL-VVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
V LA Y A ++LSL G ++ VR GW GE + G FP V+ +
Sbjct: 3 VLVLAGYRAQKEDELSLAPGDVVRQVRWVPARGWLRGEFGGR-----YGLFPERLVQEIP 57
Query: 1221 SSGRTSGRTTPVLSSKMDALPTETVIDK--VVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+ R SG ++ P + + + Y+ + ADEL + +I+ + +
Sbjct: 58 ETLRGSGEARRPRCARRRGHPAKHPRPQRWCKVNFSYSPEQADELKLQAGEIVEMIKEIE 117
Query: 1279 DPAWWQGELRGMVGLFPSNYVTKL 1302
D WW G+ G +G FPSN+V L
Sbjct: 118 D-GWWLGKKNGQLGAFPSNFVELL 140
Score = 50.4 bits (115), Expect = 4e-05
Identities = 47/176 (26%), Positives = 72/176 (40%), Gaps = 25/176 (14%)
Query: 882 PQPPRWRCV-YPFVGRSADELSVQPGDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESYVE 940
P+P RW V + + ADEL +Q G+++ GQ G FP ++VE
Sbjct: 82 PRPQRWCKVNFSYSPEQADELKLQAGEIV---EMIKEIEDGWWLGKKNGQLGAFPSNFVE 138
Query: 941 DLNA-PTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVED 999
L++ P + + ++ P Q S L P D +TVS P
Sbjct: 139 LLDSGPPSLGNPDMPSVSPGPQ--------RPPKLSSLAYDSPP--DYLQTVSHP----- 183
Query: 1000 DGEFYIASYPYSSSEPGDLVFEAGERIEVVRR---DGDWWTGRIGARTGIFPSNYV 1052
E Y + Y P +L G+ ++V+ + D WW G R G+FP N+V
Sbjct: 184 --EVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFV 237
Score = 42.7 bits (96), Expect = 0.008
Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 7/72 (9%)
Query: 1147 DSGRDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKA--DSGWWEGELQAKGR 1204
DS D + E+ + L Y +P++L+L +G ++ V K D GWWEGE Q GR
Sbjct: 171 DSPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQ--GR 228
Query: 1205 NRQVGWFPASYV 1216
G FP ++V
Sbjct: 229 R---GVFPDNFV 237
Score = 37.9 bits (84), Expect = 0.24
Identities = 19/55 (34%), Positives = 26/55 (47%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+V+ L Y AQ DELS D++ W +GE G GLFP V ++
Sbjct: 2 EVLVLAGYRAQKEDELSLAPGDVVRQVRWVPARGWLRGEFGGRYGLFPERLVQEI 56
>BC011883-1|AAH11883.1| 645|Homo sapiens SORBS2 protein protein.
Length = 645
Score = 69.3 bits (162), Expect = 8e-11
Identities = 57/166 (34%), Positives = 81/166 (48%), Gaps = 27/166 (16%)
Query: 1160 EIVQALASYT--ATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
EI +A+A Y A + +LSL KG +++ K+ D W+EG++ G NRQ G FP SYV+
Sbjct: 484 EIGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKI--PGTNRQ-GIFPVSYVE 540
Query: 1218 VLQ--SSGRTSGRTTPV-----------LSSKMDALPTETVI------DKVVALYPYTAQ 1258
V++ + G P+ LSS P T + ALY YT +
Sbjct: 541 VVKKNTKGAEDYPDPPIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGGEPFQALYNYTPR 600
Query: 1259 NADELSFEKDDIIAVTDRSQDPAWWQGELR--GMVGLFPSNYVTKL 1302
N DEL + D+I V ++ D W+ G R G FP NYV +L
Sbjct: 601 NEDELELRESDVIDVMEKCDD-GWFVGTSRRTKFFGTFPGNYVKRL 645
Score = 62.9 bits (146), Expect = 7e-09
Identities = 56/192 (29%), Positives = 86/192 (44%), Gaps = 22/192 (11%)
Query: 1115 LAQDQKSSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRR----KHEI-VQALASYT 1169
L + SS+P S A D D GR + RR K ++ +A+ +
Sbjct: 363 LTKSFTSSSPSSPSRAK--DRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFK 420
Query: 1170 ATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRT 1229
A + ++LS KG + + +K D W+EGE + +VG FP SYV+ L +
Sbjct: 421 AQTSKELSFKKGDTVYILRKIDQNWYEGE-----HHGRVGIFPISYVEKLTPPEKAQPAR 475
Query: 1230 TPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRG 1289
P A P E I + +A Y + A ELS K D + + R D W++G++ G
Sbjct: 476 PP-----PPAQPGE--IGEAIAKYNFNADTNVELSLRKGDRVILLKR-VDQNWYEGKIPG 527
Query: 1290 --MVGLFPSNYV 1299
G+FP +YV
Sbjct: 528 TNRQGIFPVSYV 539
Score = 56.4 bits (130), Expect = 6e-07
Identities = 45/136 (33%), Positives = 64/136 (47%), Gaps = 15/136 (11%)
Query: 1167 SYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTS 1226
S + TSP ++ L G + K S +AK R P SY L GR++
Sbjct: 345 SASRTSPGRVDL-PGSSTTLTKSFTSSSPSSPSRAKDRES-----PRSYSSTLTDMGRSA 398
Query: 1227 GRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGE 1286
R K + LP + A+Y + AQ + ELSF+K D + + R D W++GE
Sbjct: 399 PRERRGTPEK-EKLPAK-------AVYDFKAQTSKELSFKKGDTVYIL-RKIDQNWYEGE 449
Query: 1287 LRGMVGLFPSNYVTKL 1302
G VG+FP +YV KL
Sbjct: 450 HHGRVGIFPISYVEKL 465
Score = 39.1 bits (87), Expect = 0.10
Identities = 17/54 (31%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYVSREAAP 1058
A Y + + +L F+ G+ + ++R+ D +W+ G R GIFP +YV + P
Sbjct: 415 AVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPP 468
Score = 37.5 bits (83), Expect = 0.31
Identities = 34/132 (25%), Positives = 55/132 (41%), Gaps = 7/132 (5%)
Query: 928 RGQSGWFPESYVEDLNAPTAFVTEVIETLEPKTQ-LEGIAEVPEQEA-TSDLGGALPAVV 985
R W+ E + N F +E ++ T+ E + P + +SD +L +
Sbjct: 515 RVDQNWY-EGKIPGTNRQGIFPVSYVEVVKKNTKGAEDYPDPPIPHSYSSDRIHSLSSN- 572
Query: 986 DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGART- 1044
P R V +++ GE + A Y Y+ +L + I+V+ + D W RT
Sbjct: 573 KPQRPVFTHENIQGGGEPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTK 632
Query: 1045 --GIFPSNYVSR 1054
G FP NYV R
Sbjct: 633 FFGTFPGNYVKR 644
>AF049884-1|AAC05508.1| 666|Homo sapiens Arg/Abl-interacting protein
ArgBP2a protein.
Length = 666
Score = 69.3 bits (162), Expect = 8e-11
Identities = 57/166 (34%), Positives = 81/166 (48%), Gaps = 27/166 (16%)
Query: 1160 EIVQALASYT--ATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
EI +A+A Y A + +LSL KG +++ K+ D W+EG++ G NRQ G FP SYV+
Sbjct: 505 EIGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKI--PGTNRQ-GIFPVSYVE 561
Query: 1218 VLQ--SSGRTSGRTTPV-----------LSSKMDALPTETVI------DKVVALYPYTAQ 1258
V++ + G P+ LSS P T + ALY YT +
Sbjct: 562 VVKKNTKGAEDYPDPPIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGGEPFQALYNYTPR 621
Query: 1259 NADELSFEKDDIIAVTDRSQDPAWWQGELR--GMVGLFPSNYVTKL 1302
N DEL + D+I V ++ D W+ G R G FP NYV +L
Sbjct: 622 NEDELELRESDVIDVMEKCDD-GWFVGTSRRTKFFGTFPGNYVKRL 666
Score = 62.9 bits (146), Expect = 7e-09
Identities = 56/192 (29%), Positives = 86/192 (44%), Gaps = 22/192 (11%)
Query: 1115 LAQDQKSSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRR----KHEI-VQALASYT 1169
L + SS+P S A D D GR + RR K ++ +A+ +
Sbjct: 384 LTKSFTSSSPSSPSRAK--DRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFK 441
Query: 1170 ATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRT 1229
A + ++LS KG + + +K D W+EGE + +VG FP SYV+ L +
Sbjct: 442 AQTSKELSFKKGDTVYILRKIDQNWYEGE-----HHGRVGIFPISYVEKLTPPEKAQPAR 496
Query: 1230 TPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRG 1289
P A P E I + +A Y + A ELS K D + + R D W++G++ G
Sbjct: 497 PP-----PPAQPGE--IGEAIAKYNFNADTNVELSLRKGDRVILLKR-VDQNWYEGKIPG 548
Query: 1290 --MVGLFPSNYV 1299
G+FP +YV
Sbjct: 549 TNRQGIFPVSYV 560
Score = 56.4 bits (130), Expect = 6e-07
Identities = 45/136 (33%), Positives = 64/136 (47%), Gaps = 15/136 (11%)
Query: 1167 SYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTS 1226
S + TSP ++ L G + K S +AK R P SY L GR++
Sbjct: 366 SASRTSPGRVDL-PGSSTTLTKSFTSSSPSSPSRAKDRES-----PRSYSSTLTDMGRSA 419
Query: 1227 GRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGE 1286
R K + LP + A+Y + AQ + ELSF+K D + + R D W++GE
Sbjct: 420 PRERRGTPEK-EKLPAK-------AVYDFKAQTSKELSFKKGDTVYIL-RKIDQNWYEGE 470
Query: 1287 LRGMVGLFPSNYVTKL 1302
G VG+FP +YV KL
Sbjct: 471 HHGRVGIFPISYVEKL 486
Score = 39.1 bits (87), Expect = 0.10
Identities = 17/54 (31%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYVSREAAP 1058
A Y + + +L F+ G+ + ++R+ D +W+ G R GIFP +YV + P
Sbjct: 436 AVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPP 489
Score = 37.5 bits (83), Expect = 0.31
Identities = 34/132 (25%), Positives = 55/132 (41%), Gaps = 7/132 (5%)
Query: 928 RGQSGWFPESYVEDLNAPTAFVTEVIETLEPKTQ-LEGIAEVPEQEA-TSDLGGALPAVV 985
R W+ E + N F +E ++ T+ E + P + +SD +L +
Sbjct: 536 RVDQNWY-EGKIPGTNRQGIFPVSYVEVVKKNTKGAEDYPDPPIPHSYSSDRIHSLSSN- 593
Query: 986 DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGART- 1044
P R V +++ GE + A Y Y+ +L + I+V+ + D W RT
Sbjct: 594 KPQRPVFTHENIQGGGEPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTK 653
Query: 1045 --GIFPSNYVSR 1054
G FP NYV R
Sbjct: 654 FFGTFPGNYVKR 665
>AB018320-1|BAA34497.2| 1171|Homo sapiens KIAA0777 protein protein.
Length = 1171
Score = 69.3 bits (162), Expect = 8e-11
Identities = 57/166 (34%), Positives = 81/166 (48%), Gaps = 27/166 (16%)
Query: 1160 EIVQALASYT--ATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
EI +A+A Y A + +LSL KG +++ K+ D W+EG++ G NRQ G FP SYV+
Sbjct: 1010 EIGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKI--PGTNRQ-GIFPVSYVE 1066
Query: 1218 VLQ--SSGRTSGRTTPV-----------LSSKMDALPTETVI------DKVVALYPYTAQ 1258
V++ + G P+ LSS P T + ALY YT +
Sbjct: 1067 VVKKNTKGAEDYPDPPIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGGEPFQALYNYTPR 1126
Query: 1259 NADELSFEKDDIIAVTDRSQDPAWWQGELR--GMVGLFPSNYVTKL 1302
N DEL + D+I V ++ D W+ G R G FP NYV +L
Sbjct: 1127 NEDELELRESDVIDVMEKCDD-GWFVGTSRRTKFFGTFPGNYVKRL 1171
Score = 61.7 bits (143), Expect = 2e-08
Identities = 54/197 (27%), Positives = 84/197 (42%), Gaps = 20/197 (10%)
Query: 1110 SVTFLLAQDQKSSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRR----KHEI-VQA 1164
S +F SS + D D GR + RR K ++ +A
Sbjct: 882 SASFQDVDTANSSCHHQDRGGALQDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKA 941
Query: 1165 LASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGR 1224
+ + A + ++LS KG + + +K D W+EGE + +VG FP SYV+ L +
Sbjct: 942 VYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGE-----HHGRVGIFPISYVEKLTPPEK 996
Query: 1225 TSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQ 1284
P A P E I + +A Y + A ELS K D + + R D W++
Sbjct: 997 AQPARPP-----PPAQPGE--IGEAIAKYNFNADTNVELSLRKGDRVILLKR-VDQNWYE 1048
Query: 1285 GELRG--MVGLFPSNYV 1299
G++ G G+FP +YV
Sbjct: 1049 GKIPGTNRQGIFPVSYV 1065
Score = 55.2 bits (127), Expect = 1e-06
Identities = 34/91 (37%), Positives = 48/91 (52%), Gaps = 9/91 (9%)
Query: 1212 PASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDII 1271
P SY L GR++ R K + LP + A+Y + AQ + ELSF+K D +
Sbjct: 910 PRSYSSTLTDMGRSAPRERRGTPEK-EKLPAK-------AVYDFKAQTSKELSFKKGDTV 961
Query: 1272 AVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ R D W++GE G VG+FP +YV KL
Sbjct: 962 YIL-RKIDQNWYEGEHHGRVGIFPISYVEKL 991
Score = 39.1 bits (87), Expect = 0.10
Identities = 17/54 (31%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYVSREAAP 1058
A Y + + +L F+ G+ + ++R+ D +W+ G R GIFP +YV + P
Sbjct: 941 AVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPP 994
Score = 37.5 bits (83), Expect = 0.31
Identities = 34/132 (25%), Positives = 55/132 (41%), Gaps = 7/132 (5%)
Query: 928 RGQSGWFPESYVEDLNAPTAFVTEVIETLEPKTQ-LEGIAEVPEQEA-TSDLGGALPAVV 985
R W+ E + N F +E ++ T+ E + P + +SD +L +
Sbjct: 1041 RVDQNWY-EGKIPGTNRQGIFPVSYVEVVKKNTKGAEDYPDPPIPHSYSSDRIHSLSSN- 1098
Query: 986 DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGART- 1044
P R V +++ GE + A Y Y+ +L + I+V+ + D W RT
Sbjct: 1099 KPQRPVFTHENIQGGGEPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTK 1158
Query: 1045 --GIFPSNYVSR 1054
G FP NYV R
Sbjct: 1159 FFGTFPGNYVKR 1170
>BC050663-1|AAH50663.1| 381|Homo sapiens SH3KBP1 protein protein.
Length = 381
Score = 68.9 bits (161), Expect = 1e-10
Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 23/152 (15%)
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSG 1227
Y A ++L++ G+++ +K D GWWEG++ GR G FP ++V+ ++ +
Sbjct: 10 YQAQHDDELTISVGEIITNIRKEDGGWWEGQIN--GRR---GLFPDNFVREIKKEMKKDP 64
Query: 1228 RTTPVLSSKMDALPT-------ETVID----------KVVALYPYTAQNADELSFEKDDI 1270
T + +P+ ET++ + + Y QN DEL + DI
Sbjct: 65 LTNKAPEKPLHEVPSGNSLLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDI 124
Query: 1271 IAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
I V ++ WW+G L G G+FPSN++ +L
Sbjct: 125 IEVVGEVEE-GWWEGVLNGKTGMFPSNFIKEL 155
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 6/85 (7%)
Query: 1224 RTSGRTTPVLSSKMDALPTETVI-----DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+T G+ P ++ D+ TE D ++PY AQN DEL+ ++ DI+ + ++
Sbjct: 242 KTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDC 301
Query: 1279 -DPAWWQGELRGMVGLFPSNYVTKL 1302
D WW+GEL G G+FP N+V L
Sbjct: 302 IDVGWWEGELNGRRGVFPDNFVKLL 326
Score = 48.8 bits (111), Expect = 1e-04
Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ + + Y AQ+ DEL+ +II R +D WW+G++ G GLFP N+V ++
Sbjct: 3 EAIVEFDYQAQHDDELTISVGEIIT-NIRKEDGGWWEGQINGRRGLFPDNFVREI 56
Score = 46.8 bits (106), Expect = 5e-04
Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
I + Y + +L GE I +R+ DG WW G+I R G+FP N+V
Sbjct: 5 IVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFV 53
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 1150 RDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVG 1209
R + G R+ Q SY + ++L L G ++ V + + GWWEG L N + G
Sbjct: 91 RTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVL-----NGKTG 145
Query: 1210 WFPASYVKVLQSSGRTSG 1227
FP++++K L G
Sbjct: 146 MFPSNFIKELSGESDELG 163
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 977 LGGALPAVV-DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDG-- 1033
+G LPA P + +E S ++ +PY + +L + G+ + ++ +D
Sbjct: 244 IGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCID 303
Query: 1034 -DWWTGRIGARTGIFPSNYV 1052
WW G + R G+FP N+V
Sbjct: 304 VGWWEGELNGRRGVFPDNFV 323
Score = 41.5 bits (93), Expect = 0.019
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 1147 DSGRDSVTGRRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKG 1203
DS + + R K + + + Y A + ++L++ +G ++ + K D GWWEGEL
Sbjct: 256 DSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL---- 311
Query: 1204 RNRQVGWFPASYVKVL 1219
N + G FP ++VK+L
Sbjct: 312 -NGRRGVFPDNFVKLL 326
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 1007 SYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
++ Y +L + G+ IEVV + WW G + +TG+FPSN++
Sbjct: 106 AFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFI 152
>BC015806-1|AAH15806.1| 665|Homo sapiens SH3-domain kinase binding
protein 1 protein.
Length = 665
Score = 68.9 bits (161), Expect = 1e-10
Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 23/152 (15%)
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSG 1227
Y A ++L++ G+++ +K D GWWEG++ GR G FP ++V+ ++ +
Sbjct: 10 YQAQHDDELTISVGEIITNIRKEDGGWWEGQIN--GRR---GLFPDNFVREIKKEMKKDP 64
Query: 1228 RTTPVLSSKMDALPT-------ETVID----------KVVALYPYTAQNADELSFEKDDI 1270
T + +P+ ET++ + + Y QN DEL + DI
Sbjct: 65 LTNKAPEKPLHEVPSGNSLLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDI 124
Query: 1271 IAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
I V ++ WW+G L G G+FPSN++ +L
Sbjct: 125 IEVVGEVEE-GWWEGVLNGKTGMFPSNFIKEL 155
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 6/85 (7%)
Query: 1224 RTSGRTTPVLSSKMDALPTETVI-----DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+T G+ P ++ D+ TE D ++PY AQN DEL+ ++ DI+ + ++
Sbjct: 242 KTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDC 301
Query: 1279 -DPAWWQGELRGMVGLFPSNYVTKL 1302
D WW+GEL G G+FP N+V L
Sbjct: 302 IDVGWWEGELNGRRGVFPDNFVKLL 326
Score = 48.8 bits (111), Expect = 1e-04
Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ + + Y AQ+ DEL+ +II R +D WW+G++ G GLFP N+V ++
Sbjct: 3 EAIVEFDYQAQHDDELTISVGEIIT-NIRKEDGGWWEGQINGRRGLFPDNFVREI 56
Score = 46.8 bits (106), Expect = 5e-04
Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
I + Y + +L GE I +R+ DG WW G+I R G+FP N+V
Sbjct: 5 IVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFV 53
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 1150 RDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVG 1209
R + G R+ Q SY + ++L L G ++ V + + GWWEG L N + G
Sbjct: 91 RTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVL-----NGKTG 145
Query: 1210 WFPASYVKVLQSSGRTSG 1227
FP++++K L G
Sbjct: 146 MFPSNFIKELSGESDELG 163
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 977 LGGALPAVV-DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDG-- 1033
+G LPA P + +E S ++ +PY + +L + G+ + ++ +D
Sbjct: 244 IGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCID 303
Query: 1034 -DWWTGRIGARTGIFPSNYV 1052
WW G + R G+FP N+V
Sbjct: 304 VGWWEGELNGRRGVFPDNFV 323
Score = 41.5 bits (93), Expect = 0.019
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 1147 DSGRDSVTGRRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKG 1203
DS + + R K + + + Y A + ++L++ +G ++ + K D GWWEGEL
Sbjct: 256 DSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL---- 311
Query: 1204 RNRQVGWFPASYVKVL 1219
N + G FP ++VK+L
Sbjct: 312 -NGRRGVFPDNFVKLL 326
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 1007 SYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
++ Y +L + G+ IEVV + WW G + +TG+FPSN++
Sbjct: 106 AFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFI 152
>AY542305-1|AAT08174.1| 665|Homo sapiens GIG10 protein.
Length = 665
Score = 68.9 bits (161), Expect = 1e-10
Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 23/152 (15%)
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSG 1227
Y A ++L++ G+++ +K D GWWEG++ GR G FP ++V+ ++ +
Sbjct: 10 YQAQHDDELTISVGEIITNIRKEDGGWWEGQIN--GRR---GLFPDNFVREIKKEMKKDP 64
Query: 1228 RTTPVLSSKMDALPT-------ETVID----------KVVALYPYTAQNADELSFEKDDI 1270
T + +P+ ET++ + + Y QN DEL + DI
Sbjct: 65 LTNKAPEKPLHEVPSGNSLLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDI 124
Query: 1271 IAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
I V ++ WW+G L G G+FPSN++ +L
Sbjct: 125 IEVVGEVEE-GWWEGVLNGKTGMFPSNFIKEL 155
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 6/85 (7%)
Query: 1224 RTSGRTTPVLSSKMDALPTETVI-----DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+T G+ P ++ D+ TE D ++PY AQN DEL+ ++ DI+ + ++
Sbjct: 242 KTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDC 301
Query: 1279 -DPAWWQGELRGMVGLFPSNYVTKL 1302
D WW+GEL G G+FP N+V L
Sbjct: 302 IDVGWWEGELNGRRGVFPDNFVKLL 326
Score = 48.8 bits (111), Expect = 1e-04
Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ + + Y AQ+ DEL+ +II R +D WW+G++ G GLFP N+V ++
Sbjct: 3 EAIVEFDYQAQHDDELTISVGEIIT-NIRKEDGGWWEGQINGRRGLFPDNFVREI 56
Score = 46.8 bits (106), Expect = 5e-04
Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
I + Y + +L GE I +R+ DG WW G+I R G+FP N+V
Sbjct: 5 IVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFV 53
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 1150 RDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVG 1209
R + G R+ Q SY + ++L L G ++ V + + GWWEG L N + G
Sbjct: 91 RTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVL-----NGKTG 145
Query: 1210 WFPASYVKVLQSSGRTSG 1227
FP++++K L G
Sbjct: 146 MFPSNFIKELSGESDELG 163
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 977 LGGALPAVV-DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDG-- 1033
+G LPA P + +E S ++ +PY + +L + G+ + ++ +D
Sbjct: 244 IGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCID 303
Query: 1034 -DWWTGRIGARTGIFPSNYV 1052
WW G + R G+FP N+V
Sbjct: 304 VGWWEGELNGRRGVFPDNFV 323
Score = 41.5 bits (93), Expect = 0.019
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 1147 DSGRDSVTGRRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKG 1203
DS + + R K + + + Y A + ++L++ +G ++ + K D GWWEGEL
Sbjct: 256 DSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL---- 311
Query: 1204 RNRQVGWFPASYVKVL 1219
N + G FP ++VK+L
Sbjct: 312 -NGRRGVFPDNFVKLL 326
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 1007 SYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
++ Y +L + G+ IEVV + WW G + +TG+FPSN++
Sbjct: 106 AFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFI 152
>AY423734-1|AAS00497.1| 665|Homo sapiens migration-inducing gene 18
protein protein.
Length = 665
Score = 68.9 bits (161), Expect = 1e-10
Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 23/152 (15%)
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSG 1227
Y A ++L++ G+++ +K D GWWEG++ GR G FP ++V+ ++ +
Sbjct: 10 YQAQHDDELTISVGEIITNIRKEDGGWWEGQIN--GRR---GLFPDNFVREIKKEMKKDP 64
Query: 1228 RTTPVLSSKMDALPT-------ETVID----------KVVALYPYTAQNADELSFEKDDI 1270
T + +P+ ET++ + + Y QN DEL + DI
Sbjct: 65 LTNKAPEKPLHEVPSGNSLLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDI 124
Query: 1271 IAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
I V ++ WW+G L G G+FPSN++ +L
Sbjct: 125 IEVVGEVEE-GWWEGVLNGKTGMFPSNFIKEL 155
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 6/85 (7%)
Query: 1224 RTSGRTTPVLSSKMDALPTETVI-----DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+T G+ P ++ D+ TE D ++PY AQN DEL+ ++ DI+ + ++
Sbjct: 242 KTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDC 301
Query: 1279 -DPAWWQGELRGMVGLFPSNYVTKL 1302
D WW+GEL G G+FP N+V L
Sbjct: 302 IDVGWWEGELNGRRGVFPDNFVKLL 326
Score = 48.8 bits (111), Expect = 1e-04
Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ + + Y AQ+ DEL+ +II R +D WW+G++ G GLFP N+V ++
Sbjct: 3 EAIVEFDYQAQHDDELTISVGEIIT-NIRKEDGGWWEGQINGRRGLFPDNFVREI 56
Score = 46.8 bits (106), Expect = 5e-04
Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
I + Y + +L GE I +R+ DG WW G+I R G+FP N+V
Sbjct: 5 IVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFV 53
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 1150 RDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVG 1209
R + G R+ Q SY + ++L L G ++ V + + GWWEG L N + G
Sbjct: 91 RTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVL-----NGKTG 145
Query: 1210 WFPASYVKVLQSSGRTSG 1227
FP++++K L G
Sbjct: 146 MFPSNFIKELSGESDELG 163
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 977 LGGALPAVV-DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDG-- 1033
+G LPA P + +E S ++ +PY + +L + G+ + ++ +D
Sbjct: 244 IGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCID 303
Query: 1034 -DWWTGRIGARTGIFPSNYV 1052
WW G + R G+FP N+V
Sbjct: 304 VGWWEGELNGRRGVFPDNFV 323
Score = 41.5 bits (93), Expect = 0.019
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 1147 DSGRDSVTGRRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKG 1203
DS + + R K + + + Y A + ++L++ +G ++ + K D GWWEGEL
Sbjct: 256 DSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL---- 311
Query: 1204 RNRQVGWFPASYVKVL 1219
N + G FP ++VK+L
Sbjct: 312 -NGRRGVFPDNFVKLL 326
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 1007 SYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
++ Y +L + G+ IEVV + WW G + +TG+FPSN++
Sbjct: 106 AFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFI 152
>AL772197-2|CAH71710.1| 665|Homo sapiens SH3-domain kinase binding
protein 1 protein.
Length = 665
Score = 68.9 bits (161), Expect = 1e-10
Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 23/152 (15%)
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSG 1227
Y A ++L++ G+++ +K D GWWEG++ GR G FP ++V+ ++ +
Sbjct: 10 YQAQHDDELTISVGEIITNIRKEDGGWWEGQIN--GRR---GLFPDNFVREIKKEMKKDP 64
Query: 1228 RTTPVLSSKMDALPT-------ETVID----------KVVALYPYTAQNADELSFEKDDI 1270
T + +P+ ET++ + + Y QN DEL + DI
Sbjct: 65 LTNKAPEKPLHEVPSGNSLLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDI 124
Query: 1271 IAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
I V ++ WW+G L G G+FPSN++ +L
Sbjct: 125 IEVVGEVEE-GWWEGVLNGKTGMFPSNFIKEL 155
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 6/85 (7%)
Query: 1224 RTSGRTTPVLSSKMDALPTETVI-----DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+T G+ P ++ D+ TE D ++PY AQN DEL+ ++ DI+ + ++
Sbjct: 242 KTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDC 301
Query: 1279 -DPAWWQGELRGMVGLFPSNYVTKL 1302
D WW+GEL G G+FP N+V L
Sbjct: 302 IDVGWWEGELNGRRGVFPDNFVKLL 326
Score = 48.8 bits (111), Expect = 1e-04
Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ + + Y AQ+ DEL+ +II R +D WW+G++ G GLFP N+V ++
Sbjct: 3 EAIVEFDYQAQHDDELTISVGEIIT-NIRKEDGGWWEGQINGRRGLFPDNFVREI 56
Score = 46.8 bits (106), Expect = 5e-04
Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
I + Y + +L GE I +R+ DG WW G+I R G+FP N+V
Sbjct: 5 IVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFV 53
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 1150 RDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVG 1209
R + G R+ Q SY + ++L L G ++ V + + GWWEG L N + G
Sbjct: 91 RTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVL-----NGKTG 145
Query: 1210 WFPASYVKVLQSSGRTSG 1227
FP++++K L G
Sbjct: 146 MFPSNFIKELSGESDELG 163
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 977 LGGALPAVV-DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDG-- 1033
+G LPA P + +E S ++ +PY + +L + G+ + ++ +D
Sbjct: 244 IGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCID 303
Query: 1034 -DWWTGRIGARTGIFPSNYV 1052
WW G + R G+FP N+V
Sbjct: 304 VGWWEGELNGRRGVFPDNFV 323
Score = 41.5 bits (93), Expect = 0.019
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 1147 DSGRDSVTGRRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKG 1203
DS + + R K + + + Y A + ++L++ +G ++ + K D GWWEGEL
Sbjct: 256 DSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL---- 311
Query: 1204 RNRQVGWFPASYVKVL 1219
N + G FP ++VK+L
Sbjct: 312 -NGRRGVFPDNFVKLL 326
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 1007 SYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
++ Y +L + G+ IEVV + WW G + +TG+FPSN++
Sbjct: 106 AFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFI 152
>AL772197-1|CAH71709.1| 553|Homo sapiens SH3-domain kinase binding
protein 1 protein.
Length = 553
Score = 68.9 bits (161), Expect = 1e-10
Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 23/152 (15%)
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSG 1227
Y A ++L++ G+++ +K D GWWEG++ GR G FP ++V+ ++ +
Sbjct: 10 YQAQHDDELTISVGEIITNIRKEDGGWWEGQIN--GRR---GLFPDNFVREIKKEMKKDP 64
Query: 1228 RTTPVLSSKMDALPT-------ETVID----------KVVALYPYTAQNADELSFEKDDI 1270
T + +P+ ET++ + + Y QN DEL + DI
Sbjct: 65 LTNKAPEKPLHEVPSGNSLLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDI 124
Query: 1271 IAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
I V ++ WW+G L G G+FPSN++ +L
Sbjct: 125 IEVVGEVEE-GWWEGVLNGKTGMFPSNFIKEL 155
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 6/85 (7%)
Query: 1224 RTSGRTTPVLSSKMDALPTETVI-----DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+T G+ P ++ D+ TE D ++PY AQN DEL+ ++ DI+ + ++
Sbjct: 286 KTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDC 345
Query: 1279 -DPAWWQGELRGMVGLFPSNYVTKL 1302
D WW+GEL G G+FP N+V L
Sbjct: 346 IDVGWWEGELNGRRGVFPDNFVKLL 370
Score = 48.8 bits (111), Expect = 1e-04
Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ + + Y AQ+ DEL+ +II R +D WW+G++ G GLFP N+V ++
Sbjct: 3 EAIVEFDYQAQHDDELTISVGEIIT-NIRKEDGGWWEGQINGRRGLFPDNFVREI 56
Score = 46.8 bits (106), Expect = 5e-04
Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
I + Y + +L GE I +R+ DG WW G+I R G+FP N+V
Sbjct: 5 IVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFV 53
Score = 46.0 bits (104), Expect = 9e-04
Identities = 26/99 (26%), Positives = 47/99 (47%), Gaps = 7/99 (7%)
Query: 1150 RDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVG 1209
R + G R+ Q SY + ++L L G ++ V + + GWWEG L N + G
Sbjct: 91 RTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVL-----NGKTG 145
Query: 1210 WFPASYVKVLQSSGRTSG--RTTPVLSSKMDALPTETVI 1246
FP++++K L G + + S+ + LP +++
Sbjct: 146 MFPSNFIKELSGESDELGISQDEQLSKSRPEGLPPASLL 184
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 977 LGGALPAVV-DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDG-- 1033
+G LPA P + +E S ++ +PY + +L + G+ + ++ +D
Sbjct: 288 IGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCID 347
Query: 1034 -DWWTGRIGARTGIFPSNYV 1052
WW G + R G+FP N+V
Sbjct: 348 VGWWEGELNGRRGVFPDNFV 367
Score = 41.5 bits (93), Expect = 0.019
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 1147 DSGRDSVTGRRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKG 1203
DS + + R K + + + Y A + ++L++ +G ++ + K D GWWEGEL
Sbjct: 300 DSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL---- 355
Query: 1204 RNRQVGWFPASYVKVL 1219
N + G FP ++VK+L
Sbjct: 356 -NGRRGVFPDNFVKLL 370
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 1007 SYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
++ Y +L + G+ IEVV + WW G + +TG+FPSN++
Sbjct: 106 AFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFI 152
>AL732423-3|CAI40276.1| 665|Homo sapiens SH3-domain kinase binding
protein 1 protein.
Length = 665
Score = 68.9 bits (161), Expect = 1e-10
Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 23/152 (15%)
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSG 1227
Y A ++L++ G+++ +K D GWWEG++ GR G FP ++V+ ++ +
Sbjct: 10 YQAQHDDELTISVGEIITNIRKEDGGWWEGQIN--GRR---GLFPDNFVREIKKEMKKDP 64
Query: 1228 RTTPVLSSKMDALPT-------ETVID----------KVVALYPYTAQNADELSFEKDDI 1270
T + +P+ ET++ + + Y QN DEL + DI
Sbjct: 65 LTNKAPEKPLHEVPSGNSLLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDI 124
Query: 1271 IAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
I V ++ WW+G L G G+FPSN++ +L
Sbjct: 125 IEVVGEVEE-GWWEGVLNGKTGMFPSNFIKEL 155
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 6/85 (7%)
Query: 1224 RTSGRTTPVLSSKMDALPTETVI-----DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+T G+ P ++ D+ TE D ++PY AQN DEL+ ++ DI+ + ++
Sbjct: 242 KTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDC 301
Query: 1279 -DPAWWQGELRGMVGLFPSNYVTKL 1302
D WW+GEL G G+FP N+V L
Sbjct: 302 IDVGWWEGELNGRRGVFPDNFVKLL 326
Score = 48.8 bits (111), Expect = 1e-04
Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ + + Y AQ+ DEL+ +II R +D WW+G++ G GLFP N+V ++
Sbjct: 3 EAIVEFDYQAQHDDELTISVGEIIT-NIRKEDGGWWEGQINGRRGLFPDNFVREI 56
Score = 46.8 bits (106), Expect = 5e-04
Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
I + Y + +L GE I +R+ DG WW G+I R G+FP N+V
Sbjct: 5 IVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFV 53
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 1150 RDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVG 1209
R + G R+ Q SY + ++L L G ++ V + + GWWEG L N + G
Sbjct: 91 RTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVL-----NGKTG 145
Query: 1210 WFPASYVKVLQSSGRTSG 1227
FP++++K L G
Sbjct: 146 MFPSNFIKELSGESDELG 163
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 977 LGGALPAVV-DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDG-- 1033
+G LPA P + +E S ++ +PY + +L + G+ + ++ +D
Sbjct: 244 IGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCID 303
Query: 1034 -DWWTGRIGARTGIFPSNYV 1052
WW G + R G+FP N+V
Sbjct: 304 VGWWEGELNGRRGVFPDNFV 323
Score = 41.5 bits (93), Expect = 0.019
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 1147 DSGRDSVTGRRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKG 1203
DS + + R K + + + Y A + ++L++ +G ++ + K D GWWEGEL
Sbjct: 256 DSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL---- 311
Query: 1204 RNRQVGWFPASYVKVL 1219
N + G FP ++VK+L
Sbjct: 312 -NGRRGVFPDNFVKLL 326
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 1007 SYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
++ Y +L + G+ IEVV + WW G + +TG+FPSN++
Sbjct: 106 AFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFI 152
>AL732327-2|CAI40510.1| 665|Homo sapiens SH3-domain kinase binding
protein 1 protein.
Length = 665
Score = 68.9 bits (161), Expect = 1e-10
Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 23/152 (15%)
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSG 1227
Y A ++L++ G+++ +K D GWWEG++ GR G FP ++V+ ++ +
Sbjct: 10 YQAQHDDELTISVGEIITNIRKEDGGWWEGQIN--GRR---GLFPDNFVREIKKEMKKDP 64
Query: 1228 RTTPVLSSKMDALPT-------ETVID----------KVVALYPYTAQNADELSFEKDDI 1270
T + +P+ ET++ + + Y QN DEL + DI
Sbjct: 65 LTNKAPEKPLHEVPSGNSLLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDI 124
Query: 1271 IAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
I V ++ WW+G L G G+FPSN++ +L
Sbjct: 125 IEVVGEVEE-GWWEGVLNGKTGMFPSNFIKEL 155
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 6/85 (7%)
Query: 1224 RTSGRTTPVLSSKMDALPTETVI-----DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+T G+ P ++ D+ TE D ++PY AQN DEL+ ++ DI+ + ++
Sbjct: 242 KTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDC 301
Query: 1279 -DPAWWQGELRGMVGLFPSNYVTKL 1302
D WW+GEL G G+FP N+V L
Sbjct: 302 IDVGWWEGELNGRRGVFPDNFVKLL 326
Score = 48.8 bits (111), Expect = 1e-04
Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ + + Y AQ+ DEL+ +II R +D WW+G++ G GLFP N+V ++
Sbjct: 3 EAIVEFDYQAQHDDELTISVGEIIT-NIRKEDGGWWEGQINGRRGLFPDNFVREI 56
Score = 46.8 bits (106), Expect = 5e-04
Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
I + Y + +L GE I +R+ DG WW G+I R G+FP N+V
Sbjct: 5 IVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFV 53
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 1150 RDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVG 1209
R + G R+ Q SY + ++L L G ++ V + + GWWEG L N + G
Sbjct: 91 RTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVL-----NGKTG 145
Query: 1210 WFPASYVKVLQSSGRTSG 1227
FP++++K L G
Sbjct: 146 MFPSNFIKELSGESDELG 163
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 977 LGGALPAVV-DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDG-- 1033
+G LPA P + +E S ++ +PY + +L + G+ + ++ +D
Sbjct: 244 IGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCID 303
Query: 1034 -DWWTGRIGARTGIFPSNYV 1052
WW G + R G+FP N+V
Sbjct: 304 VGWWEGELNGRRGVFPDNFV 323
Score = 41.5 bits (93), Expect = 0.019
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 1147 DSGRDSVTGRRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKG 1203
DS + + R K + + + Y A + ++L++ +G ++ + K D GWWEGEL
Sbjct: 256 DSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL---- 311
Query: 1204 RNRQVGWFPASYVKVL 1219
N + G FP ++VK+L
Sbjct: 312 -NGRRGVFPDNFVKLL 326
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 1007 SYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
++ Y +L + G+ IEVV + WW G + +TG+FPSN++
Sbjct: 106 AFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFI 152
>AL732327-1|CAI40509.1| 553|Homo sapiens SH3-domain kinase binding
protein 1 protein.
Length = 553
Score = 68.9 bits (161), Expect = 1e-10
Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 23/152 (15%)
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSG 1227
Y A ++L++ G+++ +K D GWWEG++ GR G FP ++V+ ++ +
Sbjct: 10 YQAQHDDELTISVGEIITNIRKEDGGWWEGQIN--GRR---GLFPDNFVREIKKEMKKDP 64
Query: 1228 RTTPVLSSKMDALPT-------ETVID----------KVVALYPYTAQNADELSFEKDDI 1270
T + +P+ ET++ + + Y QN DEL + DI
Sbjct: 65 LTNKAPEKPLHEVPSGNSLLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDI 124
Query: 1271 IAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
I V ++ WW+G L G G+FPSN++ +L
Sbjct: 125 IEVVGEVEE-GWWEGVLNGKTGMFPSNFIKEL 155
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 6/85 (7%)
Query: 1224 RTSGRTTPVLSSKMDALPTETVI-----DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+T G+ P ++ D+ TE D ++PY AQN DEL+ ++ DI+ + ++
Sbjct: 286 KTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDC 345
Query: 1279 -DPAWWQGELRGMVGLFPSNYVTKL 1302
D WW+GEL G G+FP N+V L
Sbjct: 346 IDVGWWEGELNGRRGVFPDNFVKLL 370
Score = 48.8 bits (111), Expect = 1e-04
Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ + + Y AQ+ DEL+ +II R +D WW+G++ G GLFP N+V ++
Sbjct: 3 EAIVEFDYQAQHDDELTISVGEIIT-NIRKEDGGWWEGQINGRRGLFPDNFVREI 56
Score = 46.8 bits (106), Expect = 5e-04
Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
I + Y + +L GE I +R+ DG WW G+I R G+FP N+V
Sbjct: 5 IVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFV 53
Score = 46.0 bits (104), Expect = 9e-04
Identities = 26/99 (26%), Positives = 47/99 (47%), Gaps = 7/99 (7%)
Query: 1150 RDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVG 1209
R + G R+ Q SY + ++L L G ++ V + + GWWEG L N + G
Sbjct: 91 RTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVL-----NGKTG 145
Query: 1210 WFPASYVKVLQSSGRTSG--RTTPVLSSKMDALPTETVI 1246
FP++++K L G + + S+ + LP +++
Sbjct: 146 MFPSNFIKELSGESDELGISQDEQLSKSRPEGLPPASLL 184
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 977 LGGALPAVV-DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDG-- 1033
+G LPA P + +E S ++ +PY + +L + G+ + ++ +D
Sbjct: 288 IGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCID 347
Query: 1034 -DWWTGRIGARTGIFPSNYV 1052
WW G + R G+FP N+V
Sbjct: 348 VGWWEGELNGRRGVFPDNFV 367
Score = 41.5 bits (93), Expect = 0.019
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 1147 DSGRDSVTGRRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKG 1203
DS + + R K + + + Y A + ++L++ +G ++ + K D GWWEGEL
Sbjct: 300 DSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL---- 355
Query: 1204 RNRQVGWFPASYVKVL 1219
N + G FP ++VK+L
Sbjct: 356 -NGRRGVFPDNFVKLL 370
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 1007 SYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
++ Y +L + G+ IEVV + WW G + +TG+FPSN++
Sbjct: 106 AFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFI 152
>AL732325-2|CAI41253.1| 665|Homo sapiens SH3-domain kinase binding
protein 1 protein.
Length = 665
Score = 68.9 bits (161), Expect = 1e-10
Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 23/152 (15%)
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSG 1227
Y A ++L++ G+++ +K D GWWEG++ GR G FP ++V+ ++ +
Sbjct: 10 YQAQHDDELTISVGEIITNIRKEDGGWWEGQIN--GRR---GLFPDNFVREIKKEMKKDP 64
Query: 1228 RTTPVLSSKMDALPT-------ETVID----------KVVALYPYTAQNADELSFEKDDI 1270
T + +P+ ET++ + + Y QN DEL + DI
Sbjct: 65 LTNKAPEKPLHEVPSGNSLLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDI 124
Query: 1271 IAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
I V ++ WW+G L G G+FPSN++ +L
Sbjct: 125 IEVVGEVEE-GWWEGVLNGKTGMFPSNFIKEL 155
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 6/85 (7%)
Query: 1224 RTSGRTTPVLSSKMDALPTETVI-----DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+T G+ P ++ D+ TE D ++PY AQN DEL+ ++ DI+ + ++
Sbjct: 242 KTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDC 301
Query: 1279 -DPAWWQGELRGMVGLFPSNYVTKL 1302
D WW+GEL G G+FP N+V L
Sbjct: 302 IDVGWWEGELNGRRGVFPDNFVKLL 326
Score = 48.8 bits (111), Expect = 1e-04
Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ + + Y AQ+ DEL+ +II R +D WW+G++ G GLFP N+V ++
Sbjct: 3 EAIVEFDYQAQHDDELTISVGEIIT-NIRKEDGGWWEGQINGRRGLFPDNFVREI 56
Score = 46.8 bits (106), Expect = 5e-04
Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
I + Y + +L GE I +R+ DG WW G+I R G+FP N+V
Sbjct: 5 IVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFV 53
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 1150 RDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVG 1209
R + G R+ Q SY + ++L L G ++ V + + GWWEG L N + G
Sbjct: 91 RTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVL-----NGKTG 145
Query: 1210 WFPASYVKVLQSSGRTSG 1227
FP++++K L G
Sbjct: 146 MFPSNFIKELSGESDELG 163
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 977 LGGALPAVV-DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDG-- 1033
+G LPA P + +E S ++ +PY + +L + G+ + ++ +D
Sbjct: 244 IGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCID 303
Query: 1034 -DWWTGRIGARTGIFPSNYV 1052
WW G + R G+FP N+V
Sbjct: 304 VGWWEGELNGRRGVFPDNFV 323
Score = 41.5 bits (93), Expect = 0.019
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 1147 DSGRDSVTGRRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKG 1203
DS + + R K + + + Y A + ++L++ +G ++ + K D GWWEGEL
Sbjct: 256 DSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL---- 311
Query: 1204 RNRQVGWFPASYVKVL 1219
N + G FP ++VK+L
Sbjct: 312 -NGRRGVFPDNFVKLL 326
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 1007 SYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
++ Y +L + G+ IEVV + WW G + +TG+FPSN++
Sbjct: 106 AFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFI 152
>AL732325-1|CAI41252.1| 553|Homo sapiens SH3-domain kinase binding
protein 1 protein.
Length = 553
Score = 68.9 bits (161), Expect = 1e-10
Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 23/152 (15%)
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSG 1227
Y A ++L++ G+++ +K D GWWEG++ GR G FP ++V+ ++ +
Sbjct: 10 YQAQHDDELTISVGEIITNIRKEDGGWWEGQIN--GRR---GLFPDNFVREIKKEMKKDP 64
Query: 1228 RTTPVLSSKMDALPT-------ETVID----------KVVALYPYTAQNADELSFEKDDI 1270
T + +P+ ET++ + + Y QN DEL + DI
Sbjct: 65 LTNKAPEKPLHEVPSGNSLLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDI 124
Query: 1271 IAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
I V ++ WW+G L G G+FPSN++ +L
Sbjct: 125 IEVVGEVEE-GWWEGVLNGKTGMFPSNFIKEL 155
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 6/85 (7%)
Query: 1224 RTSGRTTPVLSSKMDALPTETVI-----DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+T G+ P ++ D+ TE D ++PY AQN DEL+ ++ DI+ + ++
Sbjct: 286 KTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDC 345
Query: 1279 -DPAWWQGELRGMVGLFPSNYVTKL 1302
D WW+GEL G G+FP N+V L
Sbjct: 346 IDVGWWEGELNGRRGVFPDNFVKLL 370
Score = 48.8 bits (111), Expect = 1e-04
Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ + + Y AQ+ DEL+ +II R +D WW+G++ G GLFP N+V ++
Sbjct: 3 EAIVEFDYQAQHDDELTISVGEIIT-NIRKEDGGWWEGQINGRRGLFPDNFVREI 56
Score = 46.8 bits (106), Expect = 5e-04
Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
I + Y + +L GE I +R+ DG WW G+I R G+FP N+V
Sbjct: 5 IVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFV 53
Score = 46.0 bits (104), Expect = 9e-04
Identities = 26/99 (26%), Positives = 47/99 (47%), Gaps = 7/99 (7%)
Query: 1150 RDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVG 1209
R + G R+ Q SY + ++L L G ++ V + + GWWEG L N + G
Sbjct: 91 RTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVL-----NGKTG 145
Query: 1210 WFPASYVKVLQSSGRTSG--RTTPVLSSKMDALPTETVI 1246
FP++++K L G + + S+ + LP +++
Sbjct: 146 MFPSNFIKELSGESDELGISQDEQLSKSRPEGLPPASLL 184
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 977 LGGALPAVV-DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDG-- 1033
+G LPA P + +E S ++ +PY + +L + G+ + ++ +D
Sbjct: 288 IGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCID 347
Query: 1034 -DWWTGRIGARTGIFPSNYV 1052
WW G + R G+FP N+V
Sbjct: 348 VGWWEGELNGRRGVFPDNFV 367
Score = 41.5 bits (93), Expect = 0.019
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 1147 DSGRDSVTGRRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKG 1203
DS + + R K + + + Y A + ++L++ +G ++ + K D GWWEGEL
Sbjct: 300 DSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL---- 355
Query: 1204 RNRQVGWFPASYVKVL 1219
N + G FP ++VK+L
Sbjct: 356 -NGRRGVFPDNFVKLL 370
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 1007 SYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
++ Y +L + G+ IEVV + WW G + +TG+FPSN++
Sbjct: 106 AFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFI 152
>AF230904-1|AAF37854.1| 665|Homo sapiens c-Cbl-interacting protein
protein.
Length = 665
Score = 68.9 bits (161), Expect = 1e-10
Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 23/152 (15%)
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSG 1227
Y A ++L++ G+++ +K D GWWEG++ GR G FP ++V+ ++ +
Sbjct: 10 YQAQHDDELTISVGEIITNIRKEDGGWWEGQIN--GRR---GLFPDNFVREIKKEMKKDP 64
Query: 1228 RTTPVLSSKMDALPT-------ETVID----------KVVALYPYTAQNADELSFEKDDI 1270
T + +P+ ET++ + + Y QN DEL + DI
Sbjct: 65 LTNKAPEKPLHEVPSGNSLLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDI 124
Query: 1271 IAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
I V ++ WW+G L G G+FPSN++ +L
Sbjct: 125 IEVVGEVEE-GWWEGVLNGKTGMFPSNFIKEL 155
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 6/85 (7%)
Query: 1224 RTSGRTTPVLSSKMDALPTETVI-----DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+T G+ P ++ D+ TE D ++PY AQN DEL+ ++ DI+ + ++
Sbjct: 242 KTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDC 301
Query: 1279 -DPAWWQGELRGMVGLFPSNYVTKL 1302
D WW+GEL G G+FP N+V L
Sbjct: 302 IDVGWWEGELNGRRGVFPDNFVKLL 326
Score = 48.8 bits (111), Expect = 1e-04
Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ + + Y AQ+ DEL+ +II R +D WW+G++ G GLFP N+V ++
Sbjct: 3 EAIVEFDYQAQHDDELTISVGEIIT-NIRKEDGGWWEGQINGRRGLFPDNFVREI 56
Score = 46.8 bits (106), Expect = 5e-04
Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
I + Y + +L GE I +R+ DG WW G+I R G+FP N+V
Sbjct: 5 IVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFV 53
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 1150 RDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVG 1209
R + G R+ Q SY + ++L L G ++ V + + GWWEG L N + G
Sbjct: 91 RTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVL-----NGKTG 145
Query: 1210 WFPASYVKVLQSSGRTSG 1227
FP++++K L G
Sbjct: 146 MFPSNFIKELSGESDELG 163
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 977 LGGALPAVV-DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDG-- 1033
+G LPA P + +E S ++ +PY + +L + G+ + ++ +D
Sbjct: 244 IGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCID 303
Query: 1034 -DWWTGRIGARTGIFPSNYV 1052
WW G + R G+FP N+V
Sbjct: 304 VGWWEGELNGRRGVFPDNFV 323
Score = 41.5 bits (93), Expect = 0.019
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 1147 DSGRDSVTGRRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKG 1203
DS + + R K + + + Y A + ++L++ +G ++ + K D GWWEGEL
Sbjct: 256 DSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL---- 311
Query: 1204 RNRQVGWFPASYVKVL 1219
N + G FP ++VK+L
Sbjct: 312 -NGRRGVFPDNFVKLL 326
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 1007 SYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
++ Y +L + G+ IEVV + WW G + +TG+FPSN++
Sbjct: 106 AFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFI 152
>BC021211-1|AAH21211.1| 653|Homo sapiens REPS1 protein protein.
Length = 653
Score = 68.5 bits (160), Expect = 1e-10
Identities = 34/95 (35%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADG 62
DPW I + + F+ + P +NG + G AK F +S+LP L IW L+D + DG
Sbjct: 225 DPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDG 284
Query: 63 KLDLKEFSIACKIINLKLRGLEVPKMLPPSLIASL 97
L L EF A ++ + G ++P+ LP SL+ L
Sbjct: 285 ALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKL 319
Score = 59.7 bits (138), Expect = 7e-08
Identities = 35/128 (27%), Positives = 55/128 (42%), Gaps = 1/128 (0%)
Query: 318 VTSTPIAALNKEVISKPGSVVTSPEVPMGVMSPPPMEWGVPQPQKLKYTQLFNATDRAKT 377
+T P + ++ + S T+ E+ S W + Q+ Y F
Sbjct: 191 LTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDD-PWKITDEQRQYYVNQFKTIQPDLN 249
Query: 378 GSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLGCEEFVLAMYLCEKATQGEPVPA 437
G G+ A+ +S+LP L+ IW L+D D DG L +EF A +L G +P
Sbjct: 250 GFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPE 309
Query: 438 RLPPELIP 445
+LP L+P
Sbjct: 310 KLPESLMP 317
>BC012764-1|AAH12764.1| 743|Homo sapiens RALBP1 associated Eps
domain containing 1 protein.
Length = 743
Score = 68.5 bits (160), Expect = 1e-10
Identities = 34/95 (35%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADG 62
DPW I + + F+ + P +NG + G AK F +S+LP L IW L+D + DG
Sbjct: 225 DPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDG 284
Query: 63 KLDLKEFSIACKIINLKLRGLEVPKMLPPSLIASL 97
L L EF A ++ + G ++P+ LP SL+ L
Sbjct: 285 ALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKL 319
Score = 59.7 bits (138), Expect = 7e-08
Identities = 35/128 (27%), Positives = 55/128 (42%), Gaps = 1/128 (0%)
Query: 318 VTSTPIAALNKEVISKPGSVVTSPEVPMGVMSPPPMEWGVPQPQKLKYTQLFNATDRAKT 377
+T P + ++ + S T+ E+ S W + Q+ Y F
Sbjct: 191 LTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDD-PWKITDEQRQYYVNQFKTIQPDLN 249
Query: 378 GSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLGCEEFVLAMYLCEKATQGEPVPA 437
G G+ A+ +S+LP L+ IW L+D D DG L +EF A +L G +P
Sbjct: 250 GFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPE 309
Query: 438 RLPPELIP 445
+LP L+P
Sbjct: 310 KLPESLMP 317
>AL121834-13|CAI42879.1| 743|Homo sapiens RALBP1 associated Eps
domain containing 1 protein.
Length = 743
Score = 68.5 bits (160), Expect = 1e-10
Identities = 34/95 (35%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADG 62
DPW I + + F+ + P +NG + G AK F +S+LP L IW L+D + DG
Sbjct: 225 DPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDG 284
Query: 63 KLDLKEFSIACKIINLKLRGLEVPKMLPPSLIASL 97
L L EF A ++ + G ++P+ LP SL+ L
Sbjct: 285 ALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKL 319
Score = 59.7 bits (138), Expect = 7e-08
Identities = 35/128 (27%), Positives = 55/128 (42%), Gaps = 1/128 (0%)
Query: 318 VTSTPIAALNKEVISKPGSVVTSPEVPMGVMSPPPMEWGVPQPQKLKYTQLFNATDRAKT 377
+T P + ++ + S T+ E+ S W + Q+ Y F
Sbjct: 191 LTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDD-PWKITDEQRQYYVNQFKTIQPDLN 249
Query: 378 GSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLGCEEFVLAMYLCEKATQGEPVPA 437
G G+ A+ +S+LP L+ IW L+D D DG L +EF A +L G +P
Sbjct: 250 GFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPE 309
Query: 438 RLPPELIP 445
+LP L+P
Sbjct: 310 KLPESLMP 317
>AL121834-12|CAI42877.1| 744|Homo sapiens RALBP1 associated Eps
domain containing 1 protein.
Length = 744
Score = 68.5 bits (160), Expect = 1e-10
Identities = 34/95 (35%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADG 62
DPW I + + F+ + P +NG + G AK F +S+LP L IW L+D + DG
Sbjct: 225 DPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDG 284
Query: 63 KLDLKEFSIACKIINLKLRGLEVPKMLPPSLIASL 97
L L EF A ++ + G ++P+ LP SL+ L
Sbjct: 285 ALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKL 319
Score = 59.7 bits (138), Expect = 7e-08
Identities = 35/128 (27%), Positives = 55/128 (42%), Gaps = 1/128 (0%)
Query: 318 VTSTPIAALNKEVISKPGSVVTSPEVPMGVMSPPPMEWGVPQPQKLKYTQLFNATDRAKT 377
+T P + ++ + S T+ E+ S W + Q+ Y F
Sbjct: 191 LTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDD-PWKITDEQRQYYVNQFKTIQPDLN 249
Query: 378 GSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLGCEEFVLAMYLCEKATQGEPVPA 437
G G+ A+ +S+LP L+ IW L+D D DG L +EF A +L G +P
Sbjct: 250 GFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPE 309
Query: 438 RLPPELIP 445
+LP L+P
Sbjct: 310 KLPESLMP 317
>AL121834-11|CAI42878.1| 653|Homo sapiens RALBP1 associated Eps
domain containing 1 protein.
Length = 653
Score = 68.5 bits (160), Expect = 1e-10
Identities = 34/95 (35%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADG 62
DPW I + + F+ + P +NG + G AK F +S+LP L IW L+D + DG
Sbjct: 225 DPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDG 284
Query: 63 KLDLKEFSIACKIINLKLRGLEVPKMLPPSLIASL 97
L L EF A ++ + G ++P+ LP SL+ L
Sbjct: 285 ALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKL 319
Score = 59.7 bits (138), Expect = 7e-08
Identities = 35/128 (27%), Positives = 55/128 (42%), Gaps = 1/128 (0%)
Query: 318 VTSTPIAALNKEVISKPGSVVTSPEVPMGVMSPPPMEWGVPQPQKLKYTQLFNATDRAKT 377
+T P + ++ + S T+ E+ S W + Q+ Y F
Sbjct: 191 LTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDD-PWKITDEQRQYYVNQFKTIQPDLN 249
Query: 378 GSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLGCEEFVLAMYLCEKATQGEPVPA 437
G G+ A+ +S+LP L+ IW L+D D DG L +EF A +L G +P
Sbjct: 250 GFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPE 309
Query: 438 RLPPELIP 445
+LP L+P
Sbjct: 310 KLPESLMP 317
>AF251052-1|AAK34942.1| 744|Homo sapiens RALBP1 protein.
Length = 744
Score = 68.5 bits (160), Expect = 1e-10
Identities = 34/95 (35%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADG 62
DPW I + + F+ + P +NG + G AK F +S+LP L IW L+D + DG
Sbjct: 225 DPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDG 284
Query: 63 KLDLKEFSIACKIINLKLRGLEVPKMLPPSLIASL 97
L L EF A ++ + G ++P+ LP SL+ L
Sbjct: 285 ALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKL 319
Score = 59.7 bits (138), Expect = 7e-08
Identities = 35/128 (27%), Positives = 55/128 (42%), Gaps = 1/128 (0%)
Query: 318 VTSTPIAALNKEVISKPGSVVTSPEVPMGVMSPPPMEWGVPQPQKLKYTQLFNATDRAKT 377
+T P + ++ + S T+ E+ S W + Q+ Y F
Sbjct: 191 LTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDD-PWKITDEQRQYYVNQFKTIQPDLN 249
Query: 378 GSGSGTQARSIMLQSRLPQQSLAQIWALADLDADGKLGCEEFVLAMYLCEKATQGEPVPA 437
G G+ A+ +S+LP L+ IW L+D D DG L +EF A +L G +P
Sbjct: 250 GFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPE 309
Query: 438 RLPPELIP 445
+LP L+P
Sbjct: 310 KLPESLMP 317
>U14391-1|AAA62667.1| 1109|Homo sapiens myosin-IC protein.
Length = 1109
Score = 66.1 bits (154), Expect = 8e-10
Identities = 34/80 (42%), Positives = 46/80 (57%), Gaps = 3/80 (3%)
Query: 1224 RTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPA-W 1282
+T+ R P + + + ALY Y AQ+ DELSF +DII + +DP+ W
Sbjct: 1032 QTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSFNANDIIDII--KEDPSGW 1089
Query: 1283 WQGELRGMVGLFPSNYVTKL 1302
W G LRG GLFP+NYVTK+
Sbjct: 1090 WTGRLRGKPGLFPNNYVTKI 1109
Score = 51.6 bits (118), Expect = 2e-05
Identities = 19/50 (38%), Positives = 33/50 (66%), Gaps = 1/50 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRRD-GDWWTGRIGARTGIFPSNYVSR 1054
A Y Y + + +L F A + I++++ D WWTGR+ + G+FP+NYV++
Sbjct: 1059 ALYAYDAQDTDELSFNANDIIDIIKEDPSGWWTGRLRGKPGLFPNNYVTK 1108
Score = 38.7 bits (86), Expect = 0.14
Identities = 29/107 (27%), Positives = 45/107 (42%), Gaps = 11/107 (10%)
Query: 1116 AQDQKSSTPISSEVAMITDXXXXXXXXXXXXD----SGRDSVTGRRKHEIVQ--ALASYT 1169
+ D+ S TP S + + D GR + K ++ Q AL +Y
Sbjct: 1005 SSDRVSQTPESLDFLKVPDQGAAGVRRQTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYD 1064
Query: 1170 ATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
A ++LS ++ + K+ SGWW G L+ K G FP +YV
Sbjct: 1065 AQDTDELSFNANDIIDIIKEDPSGWWTGRLRGK-----PGLFPNNYV 1106
>BC098392-1|AAH98392.1| 1108|Homo sapiens myosin IE protein.
Length = 1108
Score = 66.1 bits (154), Expect = 8e-10
Identities = 34/80 (42%), Positives = 46/80 (57%), Gaps = 3/80 (3%)
Query: 1224 RTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPA-W 1282
+T+ R P + + + ALY Y AQ+ DELSF +DII + +DP+ W
Sbjct: 1031 QTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSFNANDIIDII--KEDPSGW 1088
Query: 1283 WQGELRGMVGLFPSNYVTKL 1302
W G LRG GLFP+NYVTK+
Sbjct: 1089 WTGRLRGKQGLFPNNYVTKI 1108
Score = 51.6 bits (118), Expect = 2e-05
Identities = 19/50 (38%), Positives = 33/50 (66%), Gaps = 1/50 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRRD-GDWWTGRIGARTGIFPSNYVSR 1054
A Y Y + + +L F A + I++++ D WWTGR+ + G+FP+NYV++
Sbjct: 1058 ALYAYDAQDTDELSFNANDIIDIIKEDPSGWWTGRLRGKQGLFPNNYVTK 1107
Score = 38.7 bits (86), Expect = 0.14
Identities = 29/107 (27%), Positives = 45/107 (42%), Gaps = 11/107 (10%)
Query: 1116 AQDQKSSTPISSEVAMITDXXXXXXXXXXXXD----SGRDSVTGRRKHEIVQ--ALASYT 1169
+ D+ S TP S + + D GR + K ++ Q AL +Y
Sbjct: 1004 SSDRVSQTPESLDFLKVPDQGAAGVRRQTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYD 1063
Query: 1170 ATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
A ++LS ++ + K+ SGWW G L+ K G FP +YV
Sbjct: 1064 AQDTDELSFNANDIIDIIKEDPSGWWTGRLRGK-----QGLFPNNYV 1105
>BC010110-1|AAH10110.1| 267|Homo sapiens DKFZp434D0215 protein
protein.
Length = 267
Score = 66.1 bits (154), Expect = 8e-10
Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 14/141 (9%)
Query: 1159 HEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKV 1218
H +V L + A + L+L G+++ + +K D+ W+ G RN Q+G FPA+YVKV
Sbjct: 106 HAVV--LHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNC----RN-QIGIFPANYVKV 158
Query: 1219 LQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+ +SS + VA + Y + DELSF + +II + +
Sbjct: 159 IIDIPEGGNGKRECVSSHC------VKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVN 212
Query: 1279 DPAWWQGELRGMVGLFPSNYV 1299
+ W +GE+RG G+FP N+V
Sbjct: 213 EE-WARGEVRGRTGIFPLNFV 232
Score = 47.2 bits (107), Expect = 4e-04
Identities = 31/126 (24%), Positives = 64/126 (50%), Gaps = 8/126 (6%)
Query: 1179 MKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRTTPVLSSKMD 1238
M+G +LV+ K+ ++ + E + KG + G S +K++ R+ P S
Sbjct: 44 MRGDVLVMLKQTENNYLECQ---KGED--TGRVHLSQMKIITPLDEHL-RSRPNDPSHAQ 97
Query: 1239 ALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNY 1298
P ++ V L+ + A+ D+L+ +I+ + ++ D W++G R +G+FP+NY
Sbjct: 98 K-PVDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKI-DTDWYRGNCRNQIGIFPANY 155
Query: 1299 VTKLVN 1304
V +++
Sbjct: 156 VKVIID 161
Score = 35.5 bits (78), Expect = 1.3
Identities = 16/57 (28%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 997 VEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
V+ + + + + + DL +GE + ++ + D DW+ G + GIFP+NYV
Sbjct: 100 VDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCRNQIGIFPANYV 156
Score = 35.5 bits (78), Expect = 1.3
Identities = 30/121 (24%), Positives = 51/121 (42%), Gaps = 3/121 (2%)
Query: 934 FPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSE 993
FP V+DLN + + ++E ++ G ++ + + + G E
Sbjct: 113 FPAEQVDDLNLTSGEIVYLLEKIDTDWY-RGNCRNQIGIFPANYVKVIIDIPEGGNGKRE 171
Query: 994 PVSVED-DGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNY 1051
VS G +A + Y + +L F GE I + + +W G + RTGIFP N+
Sbjct: 172 CVSSHCVKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGRTGIFPLNF 231
Query: 1052 V 1052
V
Sbjct: 232 V 232
>BC065731-1|AAH65731.1| 390|Homo sapiens neutrophil cytosolic factor
1, (chronic granulomatous disease, autosomal 1) protein.
Length = 390
Score = 65.7 bits (153), Expect = 1e-09
Identities = 45/149 (30%), Positives = 73/149 (48%), Gaps = 18/149 (12%)
Query: 1153 VTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFP 1212
+TG + +A+A+Y TS +++L G ++ V +K++SGWW +++AK GW P
Sbjct: 152 ITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR-----GWIP 206
Query: 1213 ASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIA 1272
AS+++ L S T D P + VA+ YTA DE+S + + +
Sbjct: 207 ASFLEPLDSPDETE-----------DPEPNYAG-EPYVAIKAYTAVEGDEVSLLEGEAVE 254
Query: 1273 VTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
V + D WW + G FPS Y+ K
Sbjct: 255 VIHKLLD-GWWVIRKDDVTGYFPSMYLQK 282
Score = 38.7 bits (86), Expect = 0.14
Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 3/56 (5%)
Query: 1001 GEFYIASYPYSSSEPGDLVFEAGERIEVVRR--DGDWWTGRIGARTGIFPSNYVSR 1054
GE Y+A Y++ E ++ GE +EV+ + DG WW R TG FPS Y+ +
Sbjct: 228 GEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDG-WWVIRKDDVTGYFPSMYLQK 282
>BC002816-1|AAH02816.1| 390|Homo sapiens neutrophil cytosolic factor
1, (chronic granulomatous disease, autosomal 1) protein.
Length = 390
Score = 65.7 bits (153), Expect = 1e-09
Identities = 45/149 (30%), Positives = 73/149 (48%), Gaps = 18/149 (12%)
Query: 1153 VTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFP 1212
+TG + +A+A+Y TS +++L G ++ V +K++SGWW +++AK GW P
Sbjct: 152 ITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR-----GWIP 206
Query: 1213 ASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIA 1272
AS+++ L S T D P + VA+ YTA DE+S + + +
Sbjct: 207 ASFLEPLDSPDETE-----------DPEPNYAG-EPYVAIKAYTAVEGDEVSLLEGEAVE 254
Query: 1273 VTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
V + D WW + G FPS Y+ K
Sbjct: 255 VIHKLLD-GWWVIRKDDVTGYFPSMYLQK 282
Score = 38.7 bits (86), Expect = 0.14
Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 3/56 (5%)
Query: 1001 GEFYIASYPYSSSEPGDLVFEAGERIEVVRR--DGDWWTGRIGARTGIFPSNYVSR 1054
GE Y+A Y++ E ++ GE +EV+ + DG WW R TG FPS Y+ +
Sbjct: 228 GEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDG-WWVIRKDDVTGYFPSMYLQK 282
>AY358478-1|AAQ88842.1| 370|Homo sapiens QLAK737 protein.
Length = 370
Score = 65.7 bits (153), Expect = 1e-09
Identities = 44/139 (31%), Positives = 76/139 (54%), Gaps = 12/139 (8%)
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSG 1227
Y A ++L++ +G+ L V ++ D+ W ++A+ ++ +VG+ P Y+ S S
Sbjct: 159 YQAGREDELTITEGEWLEVIEEGDADEW---VKARNQHGEVGFVPERYLNFPDLSLPESS 215
Query: 1228 RTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQ---DPAWWQ 1284
+ + + A PT + ALY YT Q+A+ELSF + +I + R+Q D +W+
Sbjct: 216 QDS---DNPCGAEPTAFLAQ---ALYSYTGQSAEELSFPEGALIRLLPRAQDGVDDGFWR 269
Query: 1285 GELRGMVGLFPSNYVTKLV 1303
GE G VG+FPS V +L+
Sbjct: 270 GEFGGRVGVFPSLLVEELL 288
Score = 36.7 bits (81), Expect = 0.55
Identities = 24/63 (38%), Positives = 34/63 (53%), Gaps = 9/63 (14%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKA----DSGWWEGELQAKGRNRQVGWFPASYV 1216
+ QAL SYT S E+LS +G L+ + +A D G+W GE + VG FP+ V
Sbjct: 230 LAQALYSYTGQSAEELSFPEGALIRLLPRAQDGVDDGFWRGEFGGR-----VGVFPSLLV 284
Query: 1217 KVL 1219
+ L
Sbjct: 285 EEL 287
Score = 34.7 bits (76), Expect = 2.2
Identities = 21/70 (30%), Positives = 27/70 (38%), Gaps = 5/70 (7%)
Query: 994 PVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-----DGDWWTGRIGARTGIFP 1048
P E A Y Y+ +L F G I ++ R D +W G G R G+FP
Sbjct: 221 PCGAEPTAFLAQALYSYTGQSAEELSFPEGALIRLLPRAQDGVDDGFWRGEFGGRVGVFP 280
Query: 1049 SNYVSREAAP 1058
S V P
Sbjct: 281 SLLVEELLGP 290
>AY217346-1|AAO45099.1| 690|Homo sapiens FLJ00007-like protein
protein.
Length = 690
Score = 65.7 bits (153), Expect = 1e-09
Identities = 44/139 (31%), Positives = 76/139 (54%), Gaps = 12/139 (8%)
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSG 1227
Y A ++L++ +G+ L V ++ D+ W ++A+ ++ +VG+ P Y+ S S
Sbjct: 479 YQAGREDELTITEGEWLEVIEEGDADEW---VKARNQHGEVGFVPERYLNFPDLSLPESS 535
Query: 1228 RTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQ---DPAWWQ 1284
+ + + A PT + ALY YT Q+A+ELSF + +I + R+Q D +W+
Sbjct: 536 QDS---DNPCGAEPTAFLAQ---ALYSYTGQSAEELSFPEGALIRLLPRAQDGVDDGFWR 589
Query: 1285 GELRGMVGLFPSNYVTKLV 1303
GE G VG+FPS V +L+
Sbjct: 590 GEFGGRVGVFPSLLVEELL 608
Score = 36.7 bits (81), Expect = 0.55
Identities = 24/63 (38%), Positives = 34/63 (53%), Gaps = 9/63 (14%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKA----DSGWWEGELQAKGRNRQVGWFPASYV 1216
+ QAL SYT S E+LS +G L+ + +A D G+W GE + VG FP+ V
Sbjct: 550 LAQALYSYTGQSAEELSFPEGALIRLLPRAQDGVDDGFWRGEFGGR-----VGVFPSLLV 604
Query: 1217 KVL 1219
+ L
Sbjct: 605 EEL 607
Score = 34.7 bits (76), Expect = 2.2
Identities = 21/70 (30%), Positives = 27/70 (38%), Gaps = 5/70 (7%)
Query: 994 PVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-----DGDWWTGRIGARTGIFP 1048
P E A Y Y+ +L F G I ++ R D +W G G R G+FP
Sbjct: 541 PCGAEPTAFLAQALYSYTGQSAEELSFPEGALIRLLPRAQDGVDDGFWRGEFGGRVGVFP 600
Query: 1049 SNYVSREAAP 1058
S V P
Sbjct: 601 SLLVEELLGP 610
>AK223217-1|BAD96937.1| 390|Homo sapiens neutrophil cytosolic factor
1 variant protein.
Length = 390
Score = 65.7 bits (153), Expect = 1e-09
Identities = 45/149 (30%), Positives = 73/149 (48%), Gaps = 18/149 (12%)
Query: 1153 VTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFP 1212
+TG + +A+A+Y TS +++L G ++ V +K++SGWW +++AK GW P
Sbjct: 152 ITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR-----GWIP 206
Query: 1213 ASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIA 1272
AS+++ L S T D P + VA+ YTA DE+S + + +
Sbjct: 207 ASFLEPLDSPDETE-----------DPEPNYAG-EPYVAIKAYTAVEGDEVSLLEGEAVE 254
Query: 1273 VTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
V + D WW + G FPS Y+ K
Sbjct: 255 VIHKLLD-GWWVIRKDDVTGYFPSMYLQK 282
Score = 38.7 bits (86), Expect = 0.14
Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 3/56 (5%)
Query: 1001 GEFYIASYPYSSSEPGDLVFEAGERIEVVRR--DGDWWTGRIGARTGIFPSNYVSR 1054
GE Y+A Y++ E ++ GE +EV+ + DG WW R TG FPS Y+ +
Sbjct: 228 GEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDG-WWVIRKDDVTGYFPSMYLQK 282
>AK000007-1|BAA92232.1| 701|Homo sapiens FLJ00007 protein protein.
Length = 701
Score = 65.7 bits (153), Expect = 1e-09
Identities = 44/139 (31%), Positives = 76/139 (54%), Gaps = 12/139 (8%)
Query: 1168 YTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSG 1227
Y A ++L++ +G+ L V ++ D+ W ++A+ ++ +VG+ P Y+ S S
Sbjct: 490 YQAGREDELTITEGEWLEVIEEGDADEW---VKARNQHGEVGFVPERYLNFPDLSLPESS 546
Query: 1228 RTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQ---DPAWWQ 1284
+ + + A PT + ALY YT Q+A+ELSF + +I + R+Q D +W+
Sbjct: 547 QDS---DNPCGAEPTAFLAQ---ALYSYTGQSAEELSFPEGALIRLLPRAQDGVDDGFWR 600
Query: 1285 GELRGMVGLFPSNYVTKLV 1303
GE G VG+FPS V +L+
Sbjct: 601 GEFGGRVGVFPSLLVEELL 619
Score = 36.7 bits (81), Expect = 0.55
Identities = 24/63 (38%), Positives = 34/63 (53%), Gaps = 9/63 (14%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKA----DSGWWEGELQAKGRNRQVGWFPASYV 1216
+ QAL SYT S E+LS +G L+ + +A D G+W GE + VG FP+ V
Sbjct: 561 LAQALYSYTGQSAEELSFPEGALIRLLPRAQDGVDDGFWRGEFGGR-----VGVFPSLLV 615
Query: 1217 KVL 1219
+ L
Sbjct: 616 EEL 618
Score = 34.7 bits (76), Expect = 2.2
Identities = 21/70 (30%), Positives = 27/70 (38%), Gaps = 5/70 (7%)
Query: 994 PVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-----DGDWWTGRIGARTGIFP 1048
P E A Y Y+ +L F G I ++ R D +W G G R G+FP
Sbjct: 552 PCGAEPTAFLAQALYSYTGQSAEELSFPEGALIRLLPRAQDGVDDGFWRGEFGGRVGVFP 611
Query: 1049 SNYVSREAAP 1058
S V P
Sbjct: 612 SLLVEELLGP 621
>AC083884-6|AAS07465.1| 390|Homo sapiens unknown protein.
Length = 390
Score = 65.7 bits (153), Expect = 1e-09
Identities = 45/149 (30%), Positives = 73/149 (48%), Gaps = 18/149 (12%)
Query: 1153 VTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFP 1212
+TG + +A+A+Y TS +++L G ++ V +K++SGWW +++AK GW P
Sbjct: 152 ITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR-----GWIP 206
Query: 1213 ASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIA 1272
AS+++ L S T D P + VA+ YTA DE+S + + +
Sbjct: 207 ASFLEPLDSPDETE-----------DPEPNYAG-EPYVAIKAYTAVEGDEVSLLEGEAVE 254
Query: 1273 VTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
V + D WW + G FPS Y+ K
Sbjct: 255 VIHKLLD-GWWVIRKDDVTGYFPSMYLQK 282
Score = 38.7 bits (86), Expect = 0.14
Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 3/56 (5%)
Query: 1001 GEFYIASYPYSSSEPGDLVFEAGERIEVVRR--DGDWWTGRIGARTGIFPSNYVSR 1054
GE Y+A Y++ E ++ GE +EV+ + DG WW R TG FPS Y+ +
Sbjct: 228 GEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDG-WWVIRKDDVTGYFPSMYLQK 282
>U57835-1|AAB95193.1| 390|Homo sapiens p47-phox protein.
Length = 390
Score = 65.3 bits (152), Expect = 1e-09
Identities = 45/149 (30%), Positives = 73/149 (48%), Gaps = 18/149 (12%)
Query: 1153 VTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFP 1212
+TG + +A+A+Y TS +++L G ++ V +K++SGWW +++AK GW P
Sbjct: 152 ITGPIILQSYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR-----GWIP 206
Query: 1213 ASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIA 1272
AS+++ L S T D P + VA+ YTA DE+S + + +
Sbjct: 207 ASFLEPLDSPDETE-----------DPEPNYAG-EPYVAIKAYTAVEGDEVSLLEGEAVE 254
Query: 1273 VTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
V + D WW + G FPS Y+ K
Sbjct: 255 VIHKLLD-GWWVIRKDDVTGYFPSMYLQK 282
Score = 38.7 bits (86), Expect = 0.14
Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 3/56 (5%)
Query: 1001 GEFYIASYPYSSSEPGDLVFEAGERIEVVRR--DGDWWTGRIGARTGIFPSNYVSR 1054
GE Y+A Y++ E ++ GE +EV+ + DG WW R TG FPS Y+ +
Sbjct: 228 GEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDG-WWVIRKDDVTGYFPSMYLQK 282
>M55067-1|AAA59901.1| 390|Homo sapiens autosomal chronic
granulomatous disease protein protein.
Length = 390
Score = 65.3 bits (152), Expect = 1e-09
Identities = 45/149 (30%), Positives = 72/149 (48%), Gaps = 18/149 (12%)
Query: 1153 VTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFP 1212
+TG + +A+A Y TS +++L G ++ V +K++SGWW +++AK GW P
Sbjct: 152 ITGPIILQTYRAIADYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR-----GWIP 206
Query: 1213 ASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIA 1272
AS+++ L S T D P + VA+ YTA DE+S + + +
Sbjct: 207 ASFLEPLDSPDETE-----------DPEPNYAG-EPYVAIKAYTAVEGDEVSLLEGEAVE 254
Query: 1273 VTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
V + D WW + G FPS Y+ K
Sbjct: 255 VIHKLLD-GWWVIRKDDVTGYFPSMYLQK 282
Score = 38.7 bits (86), Expect = 0.14
Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 3/56 (5%)
Query: 1001 GEFYIASYPYSSSEPGDLVFEAGERIEVVRR--DGDWWTGRIGARTGIFPSNYVSR 1054
GE Y+A Y++ E ++ GE +EV+ + DG WW R TG FPS Y+ +
Sbjct: 228 GEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDG-WWVIRKDDVTGYFPSMYLQK 282
>M25665-1|AAA57209.1| 390|Homo sapiens neutrophil cytosol factor 1
protein.
Length = 390
Score = 65.3 bits (152), Expect = 1e-09
Identities = 45/149 (30%), Positives = 72/149 (48%), Gaps = 18/149 (12%)
Query: 1153 VTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFP 1212
+TG + +A+A Y TS +++L G ++ V +K++SGWW +++AK GW P
Sbjct: 152 ITGPIILQTYRAIADYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR-----GWIP 206
Query: 1213 ASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIA 1272
AS+++ L S T D P + VA+ YTA DE+S + + +
Sbjct: 207 ASFLEPLDSPDETE-----------DPEPNYAG-EPYVAIKAYTAVEGDEVSLLEGEAVE 254
Query: 1273 VTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
V + D WW + G FPS Y+ K
Sbjct: 255 VIHKLLD-GWWVIRKDDVTGYFPSMYLQK 282
Score = 38.7 bits (86), Expect = 0.14
Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 3/56 (5%)
Query: 1001 GEFYIASYPYSSSEPGDLVFEAGERIEVVRR--DGDWWTGRIGARTGIFPSNYVSR 1054
GE Y+A Y++ E ++ GE +EV+ + DG WW R TG FPS Y+ +
Sbjct: 228 GEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDG-WWVIRKDDVTGYFPSMYLQK 282
>DQ314878-1|ABC40737.1| 258|Homo sapiens neutrophil cytosolic factor
1 (47kDa, chronic granulomatous disease, autosomal
protein.
Length = 258
Score = 65.3 bits (152), Expect = 1e-09
Identities = 45/149 (30%), Positives = 72/149 (48%), Gaps = 18/149 (12%)
Query: 1153 VTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFP 1212
+TG + +A+A Y TS +++L G ++ V +K++SGWW +++AK GW P
Sbjct: 20 ITGPIILQTYRAIADYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR-----GWIP 74
Query: 1213 ASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIA 1272
AS+++ L S T D P + VA+ YTA DE+S + + +
Sbjct: 75 ASFLEPLDSPDETE-----------DPEPNYAG-EPYVAIKAYTAVEGDEVSLLEGEAVE 122
Query: 1273 VTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
V + D WW + G FPS Y+ K
Sbjct: 123 VIHKLLD-GWWVIRKDDVTGYFPSMYLQK 150
Score = 38.7 bits (86), Expect = 0.14
Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 3/56 (5%)
Query: 1001 GEFYIASYPYSSSEPGDLVFEAGERIEVVRR--DGDWWTGRIGARTGIFPSNYVSR 1054
GE Y+A Y++ E ++ GE +EV+ + DG WW R TG FPS Y+ +
Sbjct: 96 GEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDG-WWVIRKDDVTGYFPSMYLQK 150
>AF330627-1|AAK19518.1| 390|Homo sapiens adaptor protein p47phox
protein.
Length = 390
Score = 65.3 bits (152), Expect = 1e-09
Identities = 45/149 (30%), Positives = 72/149 (48%), Gaps = 18/149 (12%)
Query: 1153 VTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFP 1212
+TG + +A+A Y TS +++L G ++ V +K++SGWW +++AK GW P
Sbjct: 152 ITGPIILQTYRAIADYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR-----GWIP 206
Query: 1213 ASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIA 1272
AS+++ L S T D P + VA+ YTA DE+S + + +
Sbjct: 207 ASFLEPLDSPDETE-----------DPEPNYAG-EPYVAIKAYTAVEGDEVSLLEGEAVE 254
Query: 1273 VTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
V + D WW + G FPS Y+ K
Sbjct: 255 VIHKLLD-GWWVIRKDDVTGYFPSMYLQK 282
Score = 38.7 bits (86), Expect = 0.14
Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 3/56 (5%)
Query: 1001 GEFYIASYPYSSSEPGDLVFEAGERIEVVRR--DGDWWTGRIGARTGIFPSNYVSR 1054
GE Y+A Y++ E ++ GE +EV+ + DG WW R TG FPS Y+ +
Sbjct: 228 GEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDG-WWVIRKDDVTGYFPSMYLQK 282
>AF184614-1|AAF34737.1| 390|Homo sapiens p47-phox protein.
Length = 390
Score = 65.3 bits (152), Expect = 1e-09
Identities = 45/149 (30%), Positives = 73/149 (48%), Gaps = 18/149 (12%)
Query: 1153 VTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFP 1212
+TG + +A+A+Y TS +++L G ++ V +K++SGWW +++AK GW P
Sbjct: 152 ITGPIILQSYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR-----GWIP 206
Query: 1213 ASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIA 1272
AS+++ L S T D P + VA+ YTA DE+S + + +
Sbjct: 207 ASFLEPLDSPDETE-----------DPEPNYAG-EPYVAIKAYTAVEGDEVSLLEGEAVE 254
Query: 1273 VTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
V + D WW + G FPS Y+ K
Sbjct: 255 VIHKLLD-GWWVIRKDDVTGYFPSMYLQK 282
Score = 38.7 bits (86), Expect = 0.14
Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 3/56 (5%)
Query: 1001 GEFYIASYPYSSSEPGDLVFEAGERIEVVRR--DGDWWTGRIGARTGIFPSNYVSR 1054
GE Y+A Y++ E ++ GE +EV+ + DG WW R TG FPS Y+ +
Sbjct: 228 GEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDG-WWVIRKDDVTGYFPSMYLQK 282
>AL929302-8|CAI41286.1| 659|Homo sapiens RALBP1 associated Eps
domain containing 2 protein.
Length = 659
Score = 64.9 bits (151), Expect = 2e-09
Identities = 33/91 (36%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGN-LTGEQAKRFMLQSQLPPPVLGQIWSLADTNADG 62
+PW I + + FR+L P + ++G AK F +S+L P L IW L+D + DG
Sbjct: 273 EPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDG 332
Query: 63 KLDLKEFSIACKIINLKLRGLEVPKMLPPSL 93
L L EF A +I + G +P+ LPP+L
Sbjct: 333 ALTLPEFCAAFHLIVARKNGYPLPEGLPPTL 363
Score = 60.1 bits (139), Expect = 5e-08
Identities = 32/97 (32%), Positives = 46/97 (47%)
Query: 349 SPPPMEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADL 408
S P W + + Q+ Y F + + SG+ A++ +S+L L+ IW L+D
Sbjct: 269 SYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDA 328
Query: 409 DADGKLGCEEFVLAMYLCEKATQGEPVPARLPPELIP 445
D DG L EF A +L G P+P LPP L P
Sbjct: 329 DCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQP 365
>AL732371-2|CAI40017.1| 659|Homo sapiens RALBP1 associated Eps
domain containing 2 protein.
Length = 659
Score = 64.9 bits (151), Expect = 2e-09
Identities = 33/91 (36%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGN-LTGEQAKRFMLQSQLPPPVLGQIWSLADTNADG 62
+PW I + + FR+L P + ++G AK F +S+L P L IW L+D + DG
Sbjct: 273 EPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDG 332
Query: 63 KLDLKEFSIACKIINLKLRGLEVPKMLPPSL 93
L L EF A +I + G +P+ LPP+L
Sbjct: 333 ALTLPEFCAAFHLIVARKNGYPLPEGLPPTL 363
Score = 60.1 bits (139), Expect = 5e-08
Identities = 32/97 (32%), Positives = 46/97 (47%)
Query: 349 SPPPMEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADL 408
S P W + + Q+ Y F + + SG+ A++ +S+L L+ IW L+D
Sbjct: 269 SYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDA 328
Query: 409 DADGKLGCEEFVLAMYLCEKATQGEPVPARLPPELIP 445
D DG L EF A +L G P+P LPP L P
Sbjct: 329 DCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQP 365
>AF512951-1|AAM43953.1| 520|Homo sapiens RALBP1 associated Eps
domain containing protein 2b protein.
Length = 520
Score = 64.9 bits (151), Expect = 2e-09
Identities = 33/91 (36%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGN-LTGEQAKRFMLQSQLPPPVLGQIWSLADTNADG 62
+PW I + + FR+L P + ++G AK F +S+L P L IW L+D + DG
Sbjct: 134 EPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDG 193
Query: 63 KLDLKEFSIACKIINLKLRGLEVPKMLPPSL 93
L L EF A +I + G +P+ LPP+L
Sbjct: 194 ALTLPEFCAAFHLIVARKNGYPLPEGLPPTL 224
Score = 60.1 bits (139), Expect = 5e-08
Identities = 32/97 (32%), Positives = 46/97 (47%)
Query: 349 SPPPMEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADL 408
S P W + + Q+ Y F + + SG+ A++ +S+L L+ IW L+D
Sbjct: 130 SYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDA 189
Query: 409 DADGKLGCEEFVLAMYLCEKATQGEPVPARLPPELIP 445
D DG L EF A +L G P+P LPP L P
Sbjct: 190 DCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQP 226
>AF511533-1|AAM43933.1| 659|Homo sapiens RALBP1 associated Eps
domain containing protein 2a protein.
Length = 659
Score = 64.9 bits (151), Expect = 2e-09
Identities = 33/91 (36%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGN-LTGEQAKRFMLQSQLPPPVLGQIWSLADTNADG 62
+PW I + + FR+L P + ++G AK F +S+L P L IW L+D + DG
Sbjct: 273 EPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDG 332
Query: 63 KLDLKEFSIACKIINLKLRGLEVPKMLPPSL 93
L L EF A +I + G +P+ LPP+L
Sbjct: 333 ALTLPEFCAAFHLIVARKNGYPLPEGLPPTL 363
Score = 60.1 bits (139), Expect = 5e-08
Identities = 32/97 (32%), Positives = 46/97 (47%)
Query: 349 SPPPMEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADL 408
S P W + + Q+ Y F + + SG+ A++ +S+L L+ IW L+D
Sbjct: 269 SYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDA 328
Query: 409 DADGKLGCEEFVLAMYLCEKATQGEPVPARLPPELIP 445
D DG L EF A +L G P+P LPP L P
Sbjct: 329 DCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQP 365
>AF010233-1|AAC02901.1| 521|Homo sapiens RalBP1-interacting protein
protein.
Length = 521
Score = 64.9 bits (151), Expect = 2e-09
Identities = 33/91 (36%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGN-LTGEQAKRFMLQSQLPPPVLGQIWSLADTNADG 62
+PW I + + FR+L P + ++G AK F +S+L P L IW L+D + DG
Sbjct: 135 EPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDG 194
Query: 63 KLDLKEFSIACKIINLKLRGLEVPKMLPPSL 93
L L EF A +I + G +P+ LPP+L
Sbjct: 195 ALTLPEFCAAFHLIVARKNGYPLPEGLPPTL 225
Score = 60.1 bits (139), Expect = 5e-08
Identities = 32/97 (32%), Positives = 46/97 (47%)
Query: 349 SPPPMEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADL 408
S P W + + Q+ Y F + + SG+ A++ +S+L L+ IW L+D
Sbjct: 131 SYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDA 190
Query: 409 DADGKLGCEEFVLAMYLCEKATQGEPVPARLPPELIP 445
D DG L EF A +L G P+P LPP L P
Sbjct: 191 DCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQP 227
>AB208937-1|BAD92174.1| 514|Homo sapiens RalBP1 associated Eps
domain containing protein 2 variant protein.
Length = 514
Score = 64.9 bits (151), Expect = 2e-09
Identities = 33/91 (36%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Query: 4 DPWTIQAHEHAKFSEHFRNLGPVNGN-LTGEQAKRFMLQSQLPPPVLGQIWSLADTNADG 62
+PW I + + FR+L P + ++G AK F +S+L P L IW L+D + DG
Sbjct: 181 EPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDG 240
Query: 63 KLDLKEFSIACKIINLKLRGLEVPKMLPPSL 93
L L EF A +I + G +P+ LPP+L
Sbjct: 241 ALTLPEFCAAFHLIVARKNGYPLPEGLPPTL 271
Score = 60.1 bits (139), Expect = 5e-08
Identities = 32/97 (32%), Positives = 46/97 (47%)
Query: 349 SPPPMEWGVPQPQKLKYTQLFNATDRAKTGSGSGTQARSIMLQSRLPQQSLAQIWALADL 408
S P W + + Q+ Y F + + SG+ A++ +S+L L+ IW L+D
Sbjct: 177 SYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDA 236
Query: 409 DADGKLGCEEFVLAMYLCEKATQGEPVPARLPPELIP 445
D DG L EF A +L G P+P LPP L P
Sbjct: 237 DCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQP 273
>AF330626-1|AAK19517.1| 254|Homo sapiens adaptor protein p47phox
protein.
Length = 254
Score = 64.5 bits (150), Expect = 2e-09
Identities = 45/149 (30%), Positives = 71/149 (47%), Gaps = 18/149 (12%)
Query: 1153 VTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFP 1212
+TG + +A+A Y TS +++L G ++ V +K++SGWW +++AK GW P
Sbjct: 28 ITGPIILQTYRAIADYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR-----GWIP 82
Query: 1213 ASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIA 1272
AS+++ L S T D P + VA+ YTA DE+S + + +
Sbjct: 83 ASFLEPLDSPDETE-----------DPEPNYAG-EPYVAIKAYTAVEGDEVSLLEGEAVE 130
Query: 1273 VTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
V D WW + G FPS Y+ K
Sbjct: 131 VIHELLD-GWWVIRKDDVTGYFPSMYLQK 158
Score = 37.9 bits (84), Expect = 0.24
Identities = 21/56 (37%), Positives = 30/56 (53%), Gaps = 3/56 (5%)
Query: 1001 GEFYIASYPYSSSEPGDLVFEAGERIEVVRR--DGDWWTGRIGARTGIFPSNYVSR 1054
GE Y+A Y++ E ++ GE +EV+ DG WW R TG FPS Y+ +
Sbjct: 104 GEPYVAIKAYTAVEGDEVSLLEGEAVEVIHELLDG-WWVIRKDDVTGYFPSMYLQK 158
>AF330625-1|AAK19516.1| 276|Homo sapiens adaptor protein p47phox
protein.
Length = 276
Score = 63.7 bits (148), Expect = 4e-09
Identities = 44/149 (29%), Positives = 71/149 (47%), Gaps = 18/149 (12%)
Query: 1153 VTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFP 1212
+TG + +A+A Y TS +++L G ++ V +K++SGWW +++ K GW P
Sbjct: 50 ITGPIILQTYRAIADYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKTKR-----GWIP 104
Query: 1213 ASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIA 1272
AS+++ L S T D P + VA+ YTA DE+S + + +
Sbjct: 105 ASFLEPLDSPDETE-----------DPEPNYAG-EPYVAIKAYTAVEGDEVSLLEGEAVE 152
Query: 1273 VTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
V + D WW + G FPS Y+ K
Sbjct: 153 VIHKLLD-GWWVIRKDDVTGYFPSMYLQK 180
Score = 38.7 bits (86), Expect = 0.14
Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 3/56 (5%)
Query: 1001 GEFYIASYPYSSSEPGDLVFEAGERIEVVRR--DGDWWTGRIGARTGIFPSNYVSR 1054
GE Y+A Y++ E ++ GE +EV+ + DG WW R TG FPS Y+ +
Sbjct: 126 GEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDG-WWVIRKDDVTGYFPSMYLQK 180
>AF049885-1|AAC05509.1| 640|Homo sapiens Arg/Abl-interacting protein
ArgBP2b protein.
Length = 640
Score = 62.9 bits (146), Expect = 7e-09
Identities = 56/192 (29%), Positives = 86/192 (44%), Gaps = 22/192 (11%)
Query: 1115 LAQDQKSSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGRR----KHEI-VQALASYT 1169
L + SS+P S A D D GR + RR K ++ +A+ +
Sbjct: 409 LTKSFTSSSPSSPSRAK--DRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFK 466
Query: 1170 ATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRT 1229
A + ++LS KG + + +K D W+EGE + +VG FP SYV+ L +
Sbjct: 467 AQTSKELSFKKGDTVYILRKIDQNWYEGE-----HHGRVGIFPISYVEKLTPPEKAQPAR 521
Query: 1230 TPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRG 1289
P A P E I + +A Y + A ELS K D + + R D W++G++ G
Sbjct: 522 PP-----PPAQPGE--IGEAIAKYNFNADTNVELSLRKGDRVILLKR-VDQNWYEGKIPG 573
Query: 1290 --MVGLFPSNYV 1299
G+FP +YV
Sbjct: 574 TNRQGIFPVSYV 585
Score = 56.4 bits (130), Expect = 6e-07
Identities = 45/136 (33%), Positives = 64/136 (47%), Gaps = 15/136 (11%)
Query: 1167 SYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTS 1226
S + TSP ++ L G + K S +AK R P SY L GR++
Sbjct: 391 SASRTSPGRVDL-PGSSTTLTKSFTSSSPSSPSRAKDRES-----PRSYSSTLTDMGRSA 444
Query: 1227 GRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGE 1286
R K + LP + A+Y + AQ + ELSF+K D + + R D W++GE
Sbjct: 445 PRERRGTPEK-EKLPAK-------AVYDFKAQTSKELSFKKGDTVYIL-RKIDQNWYEGE 495
Query: 1287 LRGMVGLFPSNYVTKL 1302
G VG+FP +YV KL
Sbjct: 496 HHGRVGIFPISYVEKL 511
Score = 49.2 bits (112), Expect = 1e-04
Identities = 27/65 (41%), Positives = 42/65 (64%), Gaps = 5/65 (7%)
Query: 1160 EIVQALASYT--ATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
EI +A+A Y A + +LSL KG +++ K+ D W+EG++ G NRQ G FP SYV+
Sbjct: 530 EIGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKI--PGTNRQ-GIFPVSYVE 586
Query: 1218 VLQSS 1222
V++ +
Sbjct: 587 VVKKN 591
Score = 39.1 bits (87), Expect = 0.10
Identities = 17/54 (31%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYVSREAAP 1058
A Y + + +L F+ G+ + ++R+ D +W+ G R GIFP +YV + P
Sbjct: 461 AVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPP 514
>BC091514-1|AAH91514.1| 671|Homo sapiens sorbin and SH3 domain
containing 3 protein.
Length = 671
Score = 62.1 bits (144), Expect = 1e-08
Identities = 45/147 (30%), Positives = 75/147 (51%), Gaps = 20/147 (13%)
Query: 1157 RKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
+K + + + A SP++L+L KG ++ + K+ D W EGE + ++G FPA+YV
Sbjct: 380 KKRKAARLKFDFQAQSPKELTLQKGDIVYIHKEVDKNWLEGE-----HHGRLGIFPANYV 434
Query: 1217 KVLQSSGRTSGRTTPVLSSKMDALPTETVID--KVVALYPYTAQNADELSFEKDDIIAVT 1274
+VL + P K PT V++ + VA Y + ELSF K + I +
Sbjct: 435 EVLPAD------EIP----KPIKPPTYQVLEYGEAVAQYTFKGDLEVELSFRKGEHICLI 484
Query: 1275 DRSQDPAWWQGEL--RGMVGLFPSNYV 1299
R + W++G + G G+FP++YV
Sbjct: 485 -RKVNENWYEGRITGTGRQGIFPASYV 510
Score = 44.8 bits (101), Expect = 0.002
Identities = 56/242 (23%), Positives = 88/242 (36%), Gaps = 16/242 (6%)
Query: 981 LPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGR 1039
LPA P V + GE +A Y + +L F GE I ++R+ + +W+ GR
Sbjct: 437 LPADEIPKPIKPPTYQVLEYGEA-VAQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGR 495
Query: 1040 I--GARTGIFPSNYVSREAAPAATSXXXXXXXXXXXXXXXXXXXXXXTSPPNT--TPPIP 1095
I R GIFP++YV P S P+ +P P
Sbjct: 496 ITGTGRQGIFPASYVQVSREPRLRLCDDGPQLPTSPRLTAAARSARHPSSPSALRSPADP 555
Query: 1096 ASQLIWTSNELAYTSVTFLLAQDQKSSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTG 1155
TS T +F + P + + D G S
Sbjct: 556 TDLGGQTSPR--RTGFSF----PTQEPRPQTQNLGTPGPALSHSRGPSHPLDLGTSSPNT 609
Query: 1156 RRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPAS 1214
+ H +A+ Y + ++L L +G + V ++ D GW+ G R ++ G FP +
Sbjct: 610 SQIHWTPYRAMYQYRPQNEDELELREGDRVDVMQQCDDGWFVG---VSRRTQKFGTFPGN 666
Query: 1215 YV 1216
YV
Sbjct: 667 YV 668
Score = 43.6 bits (98), Expect = 0.005
Identities = 19/50 (38%), Positives = 31/50 (62%), Gaps = 1/50 (2%)
Query: 1253 YPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ + AQ+ EL+ +K DI+ + + D W +GE G +G+FP+NYV L
Sbjct: 389 FDFQAQSPKELTLQKGDIVYI-HKEVDKNWLEGEHHGRLGIFPANYVEVL 437
Score = 38.3 bits (85), Expect = 0.18
Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 8/102 (7%)
Query: 955 TLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSE 1014
T EP+ Q + + P + G + P +D G S P + + Y A Y Y
Sbjct: 573 TQEPRPQTQNLG-TPGPALSHSRGPSHP--LDLG--TSSPNTSQIHWTPYRAMYQYRPQN 627
Query: 1015 PGDLVFEAGERIEVVRRDGDWWTGRIGART---GIFPSNYVS 1053
+L G+R++V+++ D W + RT G FP NYV+
Sbjct: 628 EDELELREGDRVDVMQQCDDGWFVGVSRRTQKFGTFPGNYVA 669
Score = 35.9 bits (79), Expect = 0.95
Identities = 20/51 (39%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELR--GMVGLFPSNYV 1299
A+Y Y QN DEL + D + V + D W+ G R G FP NYV
Sbjct: 619 AMYQYRPQNEDELELREGDRVDVMQQCDD-GWFVGVSRRTQKFGTFPGNYV 668
Score = 34.7 bits (76), Expect = 2.2
Identities = 17/53 (32%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
Query: 1008 YPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYVSREAAPA 1059
+ + + P +L + G+ + + + D +W G R GIFP+NYV E PA
Sbjct: 389 FDFQAQSPKELTLQKGDIVYIHKEVDKNWLEGEHHGRLGIFPANYV--EVLPA 439
>BC067260-1|AAH67260.2| 671|Homo sapiens sorbin and SH3 domain
containing 3 protein.
Length = 671
Score = 62.1 bits (144), Expect = 1e-08
Identities = 45/147 (30%), Positives = 75/147 (51%), Gaps = 20/147 (13%)
Query: 1157 RKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
+K + + + A SP++L+L KG ++ + K+ D W EGE + ++G FPA+YV
Sbjct: 380 KKRKAARLKFDFQAQSPKELTLQKGDIVYIHKEVDKNWLEGE-----HHGRLGIFPANYV 434
Query: 1217 KVLQSSGRTSGRTTPVLSSKMDALPTETVID--KVVALYPYTAQNADELSFEKDDIIAVT 1274
+VL + P K PT V++ + VA Y + ELSF K + I +
Sbjct: 435 EVLPAD------EIP----KPIKPPTYQVLEYGEAVAQYTFKGDLEVELSFRKGEHICLI 484
Query: 1275 DRSQDPAWWQGEL--RGMVGLFPSNYV 1299
R + W++G + G G+FP++YV
Sbjct: 485 -RKVNENWYEGRITGTGRQGIFPASYV 510
Score = 44.8 bits (101), Expect = 0.002
Identities = 56/242 (23%), Positives = 88/242 (36%), Gaps = 16/242 (6%)
Query: 981 LPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGR 1039
LPA P V + GE +A Y + +L F GE I ++R+ + +W+ GR
Sbjct: 437 LPADEIPKPIKPPTYQVLEYGEA-VAQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGR 495
Query: 1040 I--GARTGIFPSNYVSREAAPAATSXXXXXXXXXXXXXXXXXXXXXXTSPPNT--TPPIP 1095
I R GIFP++YV P S P+ +P P
Sbjct: 496 ITGTGRQGIFPASYVQVSREPRLRLCDDGPQLPTSPRLTAAARSARHPSSPSALRSPADP 555
Query: 1096 ASQLIWTSNELAYTSVTFLLAQDQKSSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTG 1155
TS T +F + P + + D G S
Sbjct: 556 TDLGGQTSPR--RTGFSF----PTQEPRPQTQNLGTPGPALSHSRGPSHPLDLGTSSPNT 609
Query: 1156 RRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPAS 1214
+ H +A+ Y + ++L L +G + V ++ D GW+ G R ++ G FP +
Sbjct: 610 SQIHWTPYRAMYQYRPQNEDELELREGDRVDVMQQCDDGWFVG---VSRRTQKFGTFPGN 666
Query: 1215 YV 1216
YV
Sbjct: 667 YV 668
Score = 43.6 bits (98), Expect = 0.005
Identities = 19/50 (38%), Positives = 31/50 (62%), Gaps = 1/50 (2%)
Query: 1253 YPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ + AQ+ EL+ +K DI+ + + D W +GE G +G+FP+NYV L
Sbjct: 389 FDFQAQSPKELTLQKGDIVYI-HKEVDKNWLEGEHHGRLGIFPANYVEVL 437
Score = 38.3 bits (85), Expect = 0.18
Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 8/102 (7%)
Query: 955 TLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSE 1014
T EP+ Q + + P + G + P +D G S P + + Y A Y Y
Sbjct: 573 TQEPRPQTQNLG-TPGPALSHSRGPSHP--LDLG--TSSPNTSQIHWTPYRAMYQYRPQN 627
Query: 1015 PGDLVFEAGERIEVVRRDGDWWTGRIGART---GIFPSNYVS 1053
+L G+R++V+++ D W + RT G FP NYV+
Sbjct: 628 EDELELREGDRVDVMQQCDDGWFVGVSRRTQKFGTFPGNYVA 669
Score = 35.9 bits (79), Expect = 0.95
Identities = 20/51 (39%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELR--GMVGLFPSNYV 1299
A+Y Y QN DEL + D + V + D W+ G R G FP NYV
Sbjct: 619 AMYQYRPQNEDELELREGDRVDVMQQCDD-GWFVGVSRRTQKFGTFPGNYV 668
Score = 34.7 bits (76), Expect = 2.2
Identities = 17/53 (32%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
Query: 1008 YPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYVSREAAPA 1059
+ + + P +L + G+ + + + D +W G R GIFP+NYV E PA
Sbjct: 389 FDFQAQSPKELTLQKGDIVYIHKEVDKNWLEGEHHGRLGIFPANYV--EVLPA 439
>BC017751-1|AAH17751.1| 330|Homo sapiens FCHSD2 protein protein.
Length = 330
Score = 62.1 bits (144), Expect = 1e-08
Identities = 46/152 (30%), Positives = 79/152 (51%), Gaps = 19/152 (12%)
Query: 1167 SYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK--------- 1217
SY A+ P++L++ + ++L V + D W ++A+ + QVG+ P Y++
Sbjct: 69 SYKASQPDELTIEEHEVLEVIEDGDMEDW---VKARNKVGQVGYVPEKYLQFPTSNSLLS 125
Query: 1218 VLQSSGRTSGRT-TPVLSSKMD----ALPTETVIDKVVALYPYTAQNADELSFEKDDIIA 1272
+LQS R+ T S++ + +L + + V ALY Y Q DELSF + II
Sbjct: 126 MLQSLAALDSRSHTSSNSTEAELVSGSLNGDASVCFVKALYDYEGQTDDELSFPEGAIIR 185
Query: 1273 VTDRSQ--DPAWWQGELRGMVGLFPSNYVTKL 1302
+ ++ D +W+GE G +G+FPS V +L
Sbjct: 186 ILNKENQDDDGFWEGEFNGRIGVFPSVLVEEL 217
>BC010146-1|AAH10146.1| 329|Homo sapiens sorbin and SH3 domain
containing 3 protein.
Length = 329
Score = 62.1 bits (144), Expect = 1e-08
Identities = 45/147 (30%), Positives = 75/147 (51%), Gaps = 20/147 (13%)
Query: 1157 RKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
+K + + + A SP++L+L KG ++ + K+ D W EGE + ++G FPA+YV
Sbjct: 38 KKRKAARLKFDFQAQSPKELTLQKGDIVYIHKEVDKNWLEGE-----HHGRLGIFPANYV 92
Query: 1217 KVLQSSGRTSGRTTPVLSSKMDALPTETVID--KVVALYPYTAQNADELSFEKDDIIAVT 1274
+VL + P K PT V++ + VA Y + ELSF K + I +
Sbjct: 93 EVLPAD------EIP----KPIKPPTYQVLEYGEAVAQYTFKGDLEVELSFRKGEHICLI 142
Query: 1275 DRSQDPAWWQGEL--RGMVGLFPSNYV 1299
R + W++G + G G+FP++YV
Sbjct: 143 -RKVNENWYEGRITGTGRQGIFPASYV 168
Score = 44.8 bits (101), Expect = 0.002
Identities = 54/241 (22%), Positives = 87/241 (36%), Gaps = 14/241 (5%)
Query: 981 LPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGR 1039
LPA P V + GE +A Y + +L F GE I ++R+ + +W+ GR
Sbjct: 95 LPADEIPKPIKPPTYQVLEYGEA-VAQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGR 153
Query: 1040 I--GARTGIFPSNYVSREAAPAATSXXXXXXXXXXXXXXXXXXXXXXTSPPNTTPPIPAS 1097
I R GIFP++YV P S P+ PA
Sbjct: 154 ITGTGRQGIFPASYVQVSREPRLRLCDDGPQLPTSPRLTAAARSARHPSSPSALRS-PAD 212
Query: 1098 QL-IWTSNELAYTSVTFLLAQDQKSSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTGR 1156
+ + T +F + P + + D G S
Sbjct: 213 PIDLGGQTSPRRTGFSF----PTQEPRPQTQNLGTPGPALSHSRGPSHPLDLGTSSPNTS 268
Query: 1157 RKH-EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASY 1215
+ H +A+ Y + ++L L +G + V ++ D GW+ G R ++ G FP +Y
Sbjct: 269 QIHWTPYRAMYQYRPQNEDELELREGDRVDVMQQCDDGWFVG---VSRRTQKFGTFPGNY 325
Query: 1216 V 1216
V
Sbjct: 326 V 326
Score = 43.6 bits (98), Expect = 0.005
Identities = 19/50 (38%), Positives = 31/50 (62%), Gaps = 1/50 (2%)
Query: 1253 YPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ + AQ+ EL+ +K DI+ + + D W +GE G +G+FP+NYV L
Sbjct: 47 FDFQAQSPKELTLQKGDIVYI-HKEVDKNWLEGEHHGRLGIFPANYVEVL 95
Score = 38.3 bits (85), Expect = 0.18
Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 8/102 (7%)
Query: 955 TLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSE 1014
T EP+ Q + + P + G + P +D G S P + + Y A Y Y
Sbjct: 231 TQEPRPQTQNLG-TPGPALSHSRGPSHP--LDLG--TSSPNTSQIHWTPYRAMYQYRPQN 285
Query: 1015 PGDLVFEAGERIEVVRRDGDWWTGRIGART---GIFPSNYVS 1053
+L G+R++V+++ D W + RT G FP NYV+
Sbjct: 286 EDELELREGDRVDVMQQCDDGWFVGVSRRTQKFGTFPGNYVA 327
Score = 35.9 bits (79), Expect = 0.95
Identities = 20/51 (39%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELR--GMVGLFPSNYV 1299
A+Y Y QN DEL + D + V + D W+ G R G FP NYV
Sbjct: 277 AMYQYRPQNEDELELREGDRVDVMQQCDD-GWFVGVSRRTQKFGTFPGNYV 326
Score = 34.7 bits (76), Expect = 2.2
Identities = 17/53 (32%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
Query: 1008 YPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYVSREAAPA 1059
+ + + P +L + G+ + + + D +W G R GIFP+NYV E PA
Sbjct: 47 FDFQAQSPKELTLQKGDIVYIHKEVDKNWLEGEHHGRLGIFPANYV--EVLPA 97
>AF064807-1|AAD32304.1| 329|Homo sapiens vinexin beta protein.
Length = 329
Score = 62.1 bits (144), Expect = 1e-08
Identities = 45/147 (30%), Positives = 75/147 (51%), Gaps = 20/147 (13%)
Query: 1157 RKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
+K + + + A SP++L+L KG ++ + K+ D W EGE + ++G FPA+YV
Sbjct: 38 KKRKAARLKFDFQAQSPKELTLQKGDIVYIHKEVDKNWLEGE-----HHGRLGIFPANYV 92
Query: 1217 KVLQSSGRTSGRTTPVLSSKMDALPTETVID--KVVALYPYTAQNADELSFEKDDIIAVT 1274
+VL + P K PT V++ + VA Y + ELSF K + I +
Sbjct: 93 EVLPAD------EIP----KPIKPPTYQVLEYGEAVAQYTFKGDLEVELSFRKGEHICLI 142
Query: 1275 DRSQDPAWWQGEL--RGMVGLFPSNYV 1299
R + W++G + G G+FP++YV
Sbjct: 143 -RKVNENWYEGRITGTGRQGIFPASYV 168
Score = 44.0 bits (99), Expect = 0.004
Identities = 56/242 (23%), Positives = 87/242 (35%), Gaps = 16/242 (6%)
Query: 981 LPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGR 1039
LPA P V + GE +A Y + +L F GE I ++R+ + +W+ GR
Sbjct: 95 LPADEIPKPIKPPTYQVLEYGEA-VAQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGR 153
Query: 1040 I--GARTGIFPSNYVSREAAPAATSXXXXXXXXXXXXXXXXXXXXXXTSPPNT--TPPIP 1095
I R GIFP++YV P S P+ +P P
Sbjct: 154 ITGTGRQGIFPASYVQVSREPRLRLCDDGPQLPTSPRLTAAARSARHPSSPSALRSPADP 213
Query: 1096 ASQLIWTSNELAYTSVTFLLAQDQKSSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTG 1155
TS T +F + P + D G S
Sbjct: 214 TDLGGQTSPR--RTGFSF----PTQEPRPQTQNFGTPGPALSHSRGPSHPLDLGTSSPNT 267
Query: 1156 RRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPAS 1214
+ H +A+ Y + ++L L +G + V ++ D GW+ G R ++ G FP +
Sbjct: 268 SQIHWTPYRAMYQYRPQNEDELELREGDRVDVMQQCDDGWFVG---VSRRTQKFGTFPGN 324
Query: 1215 YV 1216
YV
Sbjct: 325 YV 326
Score = 43.6 bits (98), Expect = 0.005
Identities = 19/50 (38%), Positives = 31/50 (62%), Gaps = 1/50 (2%)
Query: 1253 YPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ + AQ+ EL+ +K DI+ + + D W +GE G +G+FP+NYV L
Sbjct: 47 FDFQAQSPKELTLQKGDIVYI-HKEVDKNWLEGEHHGRLGIFPANYVEVL 95
Score = 37.5 bits (83), Expect = 0.31
Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 8/102 (7%)
Query: 955 TLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSE 1014
T EP+ Q + P + G + P +D G S P + + Y A Y Y
Sbjct: 231 TQEPRPQTQNFG-TPGPALSHSRGPSHP--LDLG--TSSPNTSQIHWTPYRAMYQYRPQN 285
Query: 1015 PGDLVFEAGERIEVVRRDGDWWTGRIGART---GIFPSNYVS 1053
+L G+R++V+++ D W + RT G FP NYV+
Sbjct: 286 EDELELREGDRVDVMQQCDDGWFVGVSRRTQKFGTFPGNYVA 327
Score = 35.9 bits (79), Expect = 0.95
Identities = 20/51 (39%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELR--GMVGLFPSNYV 1299
A+Y Y QN DEL + D + V + D W+ G R G FP NYV
Sbjct: 277 AMYQYRPQNEDELELREGDRVDVMQQCDD-GWFVGVSRRTQKFGTFPGNYV 326
Score = 34.7 bits (76), Expect = 2.2
Identities = 17/53 (32%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
Query: 1008 YPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYVSREAAPA 1059
+ + + P +L + G+ + + + D +W G R GIFP+NYV E PA
Sbjct: 47 FDFQAQSPKELTLQKGDIVYIHKEVDKNWLEGEHHGRLGIFPANYV--EVLPA 97
>AF037261-1|AAC09244.1| 671|Homo sapiens SH3-containing adaptor
molecule-1 protein.
Length = 671
Score = 62.1 bits (144), Expect = 1e-08
Identities = 45/147 (30%), Positives = 75/147 (51%), Gaps = 20/147 (13%)
Query: 1157 RKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
+K + + + A SP++L+L KG ++ + K+ D W EGE + ++G FPA+YV
Sbjct: 380 KKRKAARLKFDFQAQSPKELTLQKGDIVYIHKEVDKNWLEGE-----HHGRLGIFPANYV 434
Query: 1217 KVLQSSGRTSGRTTPVLSSKMDALPTETVID--KVVALYPYTAQNADELSFEKDDIIAVT 1274
+VL + P K PT V++ + VA Y + ELSF K + I +
Sbjct: 435 EVLPAD------EIP----KPIKPPTYQVLEYGEAVAQYTFKGDLEVELSFRKGEHICLI 484
Query: 1275 DRSQDPAWWQGEL--RGMVGLFPSNYV 1299
R + W++G + G G+FP++YV
Sbjct: 485 -RKVNENWYEGRITGTGRQGIFPASYV 510
Score = 44.8 bits (101), Expect = 0.002
Identities = 56/242 (23%), Positives = 88/242 (36%), Gaps = 16/242 (6%)
Query: 981 LPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGR 1039
LPA P V + GE +A Y + +L F GE I ++R+ + +W+ GR
Sbjct: 437 LPADEIPKPIKPPTYQVLEYGEA-VAQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGR 495
Query: 1040 I--GARTGIFPSNYVSREAAPAATSXXXXXXXXXXXXXXXXXXXXXXTSPPNT--TPPIP 1095
I R GIFP++YV P S P+ +P P
Sbjct: 496 ITGTGRQGIFPASYVQVSREPRLRLCDDGPQLPTSPRLTAAARSARHPSSPSALRSPADP 555
Query: 1096 ASQLIWTSNELAYTSVTFLLAQDQKSSTPISSEVAMITDXXXXXXXXXXXXDSGRDSVTG 1155
TS T +F + P + + D G S
Sbjct: 556 TDLGGQTSPR--RTGFSF----PTQEPRPQTQNLGTPGPALSHSRGPSHPLDLGTSSPNT 609
Query: 1156 RRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPAS 1214
+ H +A+ Y + ++L L +G + V ++ D GW+ G R ++ G FP +
Sbjct: 610 SQIHWTPYRAMYQYRPQNEDELELREGDRVDVMQQCDDGWFVG---VSRRTQKFGTFPGN 666
Query: 1215 YV 1216
YV
Sbjct: 667 YV 668
Score = 43.6 bits (98), Expect = 0.005
Identities = 19/50 (38%), Positives = 31/50 (62%), Gaps = 1/50 (2%)
Query: 1253 YPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ + AQ+ EL+ +K DI+ + + D W +GE G +G+FP+NYV L
Sbjct: 389 FDFQAQSPKELTLQKGDIVYI-HKEVDKNWLEGEHHGRLGIFPANYVEVL 437
Score = 38.3 bits (85), Expect = 0.18
Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 8/102 (7%)
Query: 955 TLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSE 1014
T EP+ Q + + P + G + P +D G S P + + Y A Y Y
Sbjct: 573 TQEPRPQTQNLG-TPGPALSHSRGPSHP--LDLG--TSSPNTSQIHWTPYRAMYQYRPQN 627
Query: 1015 PGDLVFEAGERIEVVRRDGDWWTGRIGART---GIFPSNYVS 1053
+L G+R++V+++ D W + RT G FP NYV+
Sbjct: 628 EDELELREGDRVDVMQQCDDGWFVGVSRRTQKFGTFPGNYVA 669
Score = 35.9 bits (79), Expect = 0.95
Identities = 20/51 (39%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELR--GMVGLFPSNYV 1299
A+Y Y QN DEL + D + V + D W+ G R G FP NYV
Sbjct: 619 AMYQYRPQNEDELELREGDRVDVMQQCDD-GWFVGVSRRTQKFGTFPGNYV 668
Score = 34.7 bits (76), Expect = 2.2
Identities = 17/53 (32%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
Query: 1008 YPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYVSREAAPA 1059
+ + + P +L + G+ + + + D +W G R GIFP+NYV E PA
Sbjct: 389 FDFQAQSPKELTLQKGDIVYIHKEVDKNWLEGEHHGRLGIFPANYV--EVLPA 439
>AB018312-1|BAA34489.2| 746|Homo sapiens KIAA0769 protein protein.
Length = 746
Score = 62.1 bits (144), Expect = 1e-08
Identities = 46/152 (30%), Positives = 79/152 (51%), Gaps = 19/152 (12%)
Query: 1167 SYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK--------- 1217
SY A+ P++L++ + ++L V + D W ++A+ + QVG+ P Y++
Sbjct: 485 SYKASQPDELTIEEHEVLEVIEDGDMEDW---VKARNKVGQVGYVPEKYLQFPTSNSLLS 541
Query: 1218 VLQSSGRTSGRT-TPVLSSKMD----ALPTETVIDKVVALYPYTAQNADELSFEKDDIIA 1272
+LQS R+ T S++ + +L + + V ALY Y Q DELSF + II
Sbjct: 542 MLQSLAALDSRSHTSSNSTEAELVSGSLNGDASVCFVKALYDYEGQTDDELSFPEGAIIR 601
Query: 1273 VTDRSQ--DPAWWQGELRGMVGLFPSNYVTKL 1302
+ ++ D +W+GE G +G+FPS V +L
Sbjct: 602 ILNKENQDDDGFWEGEFNGRIGVFPSVLVEEL 633
>X95677-1|CAA64980.1| 299|Homo sapiens argBPIB protein.
Length = 299
Score = 60.9 bits (141), Expect = 3e-08
Identities = 26/59 (44%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
++KVVA+Y YT DELSF++ II V ++ D W++G + G+ GLFP NYV +++
Sbjct: 239 LEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDD-GWYEGVMNGVTGLFPGNYVESIMH 296
Score = 44.0 bits (99), Expect = 0.004
Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
Query: 969 PEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEV 1028
P E + A+ DP P + E +A Y Y+ + +L F+ G I V
Sbjct: 207 PPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYV 266
Query: 1029 VRRDGD-WWTGRIGARTGIFPSNYV 1052
++++ D W+ G + TG+FP NYV
Sbjct: 267 IKKNDDGWYEGVMNGVTGLFPGNYV 291
Score = 42.7 bits (96), Expect = 0.008
Identities = 22/58 (37%), Positives = 32/58 (55%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS +G ++ V KK D GW+EG + N G FP +YV+
Sbjct: 240 EKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVM-----NGVTGLFPGNYVE 292
>X95632-1|CAA64885.1| 475|Homo sapiens Arg protein tyrosine
kinase-binding protein protein.
Length = 475
Score = 60.9 bits (141), Expect = 3e-08
Identities = 26/59 (44%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
++KVVA+Y YT DELSF++ II V ++ D W++G + G+ GLFP NYV +++
Sbjct: 415 LEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDD-GWYEGVMNGVTGLFPGNYVESIMH 472
Score = 44.0 bits (99), Expect = 0.004
Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
Query: 969 PEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEV 1028
P E + A+ DP P + E +A Y Y+ + +L F+ G I V
Sbjct: 383 PPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYV 442
Query: 1029 VRRDGD-WWTGRIGARTGIFPSNYV 1052
++++ D W+ G + TG+FP NYV
Sbjct: 443 IKKNDDGWYEGVMNGVTGLFPGNYV 467
Score = 42.7 bits (96), Expect = 0.008
Identities = 22/58 (37%), Positives = 32/58 (55%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS +G ++ V KK D GW+EG + N G FP +YV+
Sbjct: 416 EKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVM-----NGVTGLFPGNYVE 468
>U23435-1|AAA92289.1| 401|Homo sapiens Abl interactor 2 protein.
Length = 401
Score = 60.9 bits (141), Expect = 3e-08
Identities = 26/59 (44%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
++KVVA+Y YT DELSF++ II V ++ D W++G + G+ GLFP NYV +++
Sbjct: 341 LEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDD-GWYEGVMNGVTGLFPGNYVESIMH 398
Score = 44.0 bits (99), Expect = 0.004
Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
Query: 969 PEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEV 1028
P E + A+ DP P + E +A Y Y+ + +L F+ G I V
Sbjct: 309 PPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYV 368
Query: 1029 VRRDGD-WWTGRIGARTGIFPSNYV 1052
++++ D W+ G + TG+FP NYV
Sbjct: 369 IKKNDDGWYEGVMNGVTGLFPGNYV 393
Score = 42.7 bits (96), Expect = 0.008
Identities = 22/58 (37%), Positives = 32/58 (55%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS +G ++ V KK D GW+EG + N G FP +YV+
Sbjct: 342 EKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVM-----NGVTGLFPGNYVE 394
>BT009920-1|AAP88922.1| 475|Homo sapiens abl-interactor 2 protein.
Length = 475
Score = 60.9 bits (141), Expect = 3e-08
Identities = 26/59 (44%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
++KVVA+Y YT DELSF++ II V ++ D W++G + G+ GLFP NYV +++
Sbjct: 415 LEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDD-GWYEGVMNGVTGLFPGNYVESIMH 472
Score = 44.0 bits (99), Expect = 0.004
Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
Query: 969 PEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEV 1028
P E + A+ DP P + E +A Y Y+ + +L F+ G I V
Sbjct: 383 PPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYV 442
Query: 1029 VRRDGD-WWTGRIGARTGIFPSNYV 1052
++++ D W+ G + TG+FP NYV
Sbjct: 443 IKKNDDGWYEGVMNGVTGLFPGNYV 467
Score = 42.7 bits (96), Expect = 0.008
Identities = 22/58 (37%), Positives = 32/58 (55%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS +G ++ V KK D GW+EG + N G FP +YV+
Sbjct: 416 EKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVM-----NGVTGLFPGNYVE 468
>BC001439-1|AAH01439.1| 475|Homo sapiens abl interactor 2 protein.
Length = 475
Score = 60.9 bits (141), Expect = 3e-08
Identities = 26/59 (44%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
++KVVA+Y YT DELSF++ II V ++ D W++G + G+ GLFP NYV +++
Sbjct: 415 LEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDD-GWYEGVMNGVTGLFPGNYVESIMH 472
Score = 44.0 bits (99), Expect = 0.004
Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
Query: 969 PEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEV 1028
P E + A+ DP P + E +A Y Y+ + +L F+ G I V
Sbjct: 383 PPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYV 442
Query: 1029 VRRDGD-WWTGRIGARTGIFPSNYV 1052
++++ D W+ G + TG+FP NYV
Sbjct: 443 IKKNDDGWYEGVMNGVTGLFPGNYV 467
Score = 42.7 bits (96), Expect = 0.008
Identities = 22/58 (37%), Positives = 32/58 (55%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS +G ++ V KK D GW+EG + N G FP +YV+
Sbjct: 416 EKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVM-----NGVTGLFPGNYVE 468
>AF260261-1|AAF70308.1| 513|Homo sapiens Abl-interactor protein 2b
protein.
Length = 513
Score = 60.9 bits (141), Expect = 3e-08
Identities = 26/59 (44%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
++KVVA+Y YT DELSF++ II V ++ D W++G + G+ GLFP NYV +++
Sbjct: 453 LEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDD-GWYEGVMNGVTGLFPGNYVESIMH 510
Score = 44.0 bits (99), Expect = 0.004
Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
Query: 969 PEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEV 1028
P E + A+ DP P + E +A Y Y+ + +L F+ G I V
Sbjct: 421 PPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYV 480
Query: 1029 VRRDGD-WWTGRIGARTGIFPSNYV 1052
++++ D W+ G + TG+FP NYV
Sbjct: 481 IKKNDDGWYEGVMNGVTGLFPGNYV 505
Score = 42.7 bits (96), Expect = 0.008
Identities = 22/58 (37%), Positives = 32/58 (55%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS +G ++ V KK D GW+EG + N G FP +YV+
Sbjct: 454 EKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVM-----NGVTGLFPGNYVE 506
>AC018891-1|AAY14675.1| 321|Homo sapiens unknown protein.
Length = 321
Score = 60.9 bits (141), Expect = 3e-08
Identities = 26/59 (44%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
++KVVA+Y YT DELSF++ II V ++ D W++G + G+ GLFP NYV +++
Sbjct: 261 LEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDD-GWYEGVMNGVTGLFPGNYVESIMH 318
Score = 44.0 bits (99), Expect = 0.004
Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
Query: 969 PEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEV 1028
P E + A+ DP P + E +A Y Y+ + +L F+ G I V
Sbjct: 229 PPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYV 288
Query: 1029 VRRDGD-WWTGRIGARTGIFPSNYV 1052
++++ D W+ G + TG+FP NYV
Sbjct: 289 IKKNDDGWYEGVMNGVTGLFPGNYV 313
Score = 42.7 bits (96), Expect = 0.008
Identities = 22/58 (37%), Positives = 32/58 (55%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS +G ++ V KK D GW+EG + N G FP +YV+
Sbjct: 262 EKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVM-----NGVTGLFPGNYVE 314
>AL133355-1|CAI15351.1| 1059|Homo sapiens SH3 and PX domains 2A
protein.
Length = 1059
Score = 60.5 bits (140), Expect = 4e-08
Identities = 40/154 (25%), Positives = 70/154 (45%), Gaps = 16/154 (10%)
Query: 1148 SGRDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQ 1207
+G D+ E +++Y +LSL G+++ V +K +SGWW + +
Sbjct: 111 TGADATAEPMILEQYVVVSNYKKQENSELSLQAGEVVDVIEKNESGWW-----FVSTSEE 165
Query: 1208 VGWFPASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEK 1267
GW PA+Y++ + S T + +K V + PYT+Q+ DE+ FEK
Sbjct: 166 QGWVPATYLEAQNGTRDDSDINTSKTGEE----------EKYVTVQPYTSQSKDEIGFEK 215
Query: 1268 DDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
+ V ++ + WW G G P++Y+ K
Sbjct: 216 GVTVEVIRKNLE-GWWYIRYLGKEGWAPASYLKK 248
Score = 39.9 bits (89), Expect = 0.059
Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 6/98 (6%)
Query: 956 LEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEP 1015
L P+T E +E + ++SDL LPA P T E E Y+ Y +
Sbjct: 728 LPPQTASEAPSE-GSRRSSSDLI-TLPATTPPCPTKKE---WEGPATSYMTCSAYQKVQD 782
Query: 1016 GDLVFEAGERIEVV-RRDGDWWTGRIGARTGIFPSNYV 1052
++ F AG ++V+ +++ WW R G G PS+Y+
Sbjct: 783 SEISFPAGVEVQVLEKQESGWWYVRFGELEGWAPSHYL 820
Score = 39.1 bits (87), Expect = 0.10
Identities = 17/54 (31%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Query: 1002 EFYIASYPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYVSR 1054
E Y+ PY+S ++ FE G +EV+R++ + WW R + G P++Y+ +
Sbjct: 195 EKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKK 248
Score = 39.1 bits (87), Expect = 0.10
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 4/67 (5%)
Query: 993 EPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVV-RRDGDWWTGRIGARTGIFPSNY 1051
EP SVE E+Y + S G + F G++ EV+ + G WW +IG + G P++Y
Sbjct: 371 EPPSVEV--EYYTIAEFQSCISDG-ISFRGGQKAEVIDKNSGGWWYVQIGEKEGWAPASY 427
Query: 1052 VSREAAP 1058
+ + P
Sbjct: 428 IDKRKKP 434
>AL121929-4|CAI13961.1| 1059|Homo sapiens SH3 and PX domains 2A
protein.
Length = 1059
Score = 60.5 bits (140), Expect = 4e-08
Identities = 40/154 (25%), Positives = 70/154 (45%), Gaps = 16/154 (10%)
Query: 1148 SGRDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQ 1207
+G D+ E +++Y +LSL G+++ V +K +SGWW + +
Sbjct: 111 TGADATAEPMILEQYVVVSNYKKQENSELSLQAGEVVDVIEKNESGWW-----FVSTSEE 165
Query: 1208 VGWFPASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEK 1267
GW PA+Y++ + S T + +K V + PYT+Q+ DE+ FEK
Sbjct: 166 QGWVPATYLEAQNGTRDDSDINTSKTGEE----------EKYVTVQPYTSQSKDEIGFEK 215
Query: 1268 DDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
+ V ++ + WW G G P++Y+ K
Sbjct: 216 GVTVEVIRKNLE-GWWYIRYLGKEGWAPASYLKK 248
Score = 39.9 bits (89), Expect = 0.059
Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 6/98 (6%)
Query: 956 LEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEP 1015
L P+T E +E + ++SDL LPA P T E E Y+ Y +
Sbjct: 728 LPPQTASEAPSE-GSRRSSSDLI-TLPATTPPCPTKKE---WEGPATSYMTCSAYQKVQD 782
Query: 1016 GDLVFEAGERIEVV-RRDGDWWTGRIGARTGIFPSNYV 1052
++ F AG ++V+ +++ WW R G G PS+Y+
Sbjct: 783 SEISFPAGVEVQVLEKQESGWWYVRFGELEGWAPSHYL 820
Score = 39.1 bits (87), Expect = 0.10
Identities = 17/54 (31%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Query: 1002 EFYIASYPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYVSR 1054
E Y+ PY+S ++ FE G +EV+R++ + WW R + G P++Y+ +
Sbjct: 195 EKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKK 248
Score = 39.1 bits (87), Expect = 0.10
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 4/67 (5%)
Query: 993 EPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVV-RRDGDWWTGRIGARTGIFPSNY 1051
EP SVE E+Y + S G + F G++ EV+ + G WW +IG + G P++Y
Sbjct: 371 EPPSVEV--EYYTIAEFQSCISDG-ISFRGGQKAEVIDKNSGGWWYVQIGEKEGWAPASY 427
Query: 1052 VSREAAP 1058
+ + P
Sbjct: 428 IDKRKKP 434
>AB007878-1|BAA24848.2| 989|Homo sapiens KIAA0418 protein.
Length = 989
Score = 60.5 bits (140), Expect = 4e-08
Identities = 40/154 (25%), Positives = 70/154 (45%), Gaps = 16/154 (10%)
Query: 1148 SGRDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQ 1207
+G D+ E +++Y +LSL G+++ V +K +SGWW + +
Sbjct: 41 TGADATAEPMILEQYVVVSNYKKQENSELSLQAGEVVDVIEKNESGWW-----FVSTSEE 95
Query: 1208 VGWFPASYVKVLQSSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEK 1267
GW PA+Y++ + S T + +K V + PYT+Q+ DE+ FEK
Sbjct: 96 QGWVPATYLEAQNGTRDDSDINTSKTGEE----------EKYVTVQPYTSQSKDEIGFEK 145
Query: 1268 DDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
+ V ++ + WW G G P++Y+ K
Sbjct: 146 GVTVEVIRKNLE-GWWYIRYLGKEGWAPASYLKK 178
Score = 39.9 bits (89), Expect = 0.059
Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 6/98 (6%)
Query: 956 LEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEP 1015
L P+T E +E + ++SDL LPA P T E E Y+ Y +
Sbjct: 658 LPPQTASEAPSE-GSRRSSSDLI-TLPATTPPCPTKKE---WEGPATSYMTCSAYQKVQD 712
Query: 1016 GDLVFEAGERIEVV-RRDGDWWTGRIGARTGIFPSNYV 1052
++ F AG ++V+ +++ WW R G G PS+Y+
Sbjct: 713 SEISFPAGVEVQVLEKQESGWWYVRFGELEGWAPSHYL 750
Score = 39.1 bits (87), Expect = 0.10
Identities = 17/54 (31%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Query: 1002 EFYIASYPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYVSR 1054
E Y+ PY+S ++ FE G +EV+R++ + WW R + G P++Y+ +
Sbjct: 125 EKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKK 178
Score = 39.1 bits (87), Expect = 0.10
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 4/67 (5%)
Query: 993 EPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVV-RRDGDWWTGRIGARTGIFPSNY 1051
EP SVE E+Y + S G + F G++ EV+ + G WW +IG + G P++Y
Sbjct: 301 EPPSVEV--EYYTIAEFQSCISDG-ISFRGGQKAEVIDKNSGGWWYVQIGEKEGWAPASY 357
Query: 1052 VSREAAP 1058
+ + P
Sbjct: 358 IDKRKKP 364
>AL121929-6|CAI13963.1| 940|Homo sapiens SH3 and PX domains 2A
protein.
Length = 940
Score = 60.1 bits (139), Expect = 5e-08
Identities = 37/137 (27%), Positives = 65/137 (47%), Gaps = 16/137 (11%)
Query: 1165 LASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGR 1224
+++Y +LSL G+++ V +K +SGWW + + GW PA+Y++ +
Sbjct: 9 VSNYKKQENSELSLQAGEVVDVIEKNESGWW-----FVSTSEEQGWVPATYLEAQNGTRD 63
Query: 1225 TSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQ 1284
S T + +K V + PYT+Q+ DE+ FEK + V ++ + WW
Sbjct: 64 DSDINTSKTGEE----------EKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLE-GWWY 112
Query: 1285 GELRGMVGLFPSNYVTK 1301
G G P++Y+ K
Sbjct: 113 IRYLGKEGWAPASYLKK 129
Score = 39.9 bits (89), Expect = 0.059
Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 6/98 (6%)
Query: 956 LEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEP 1015
L P+T E +E + ++SDL LPA P T E E Y+ Y +
Sbjct: 609 LPPQTASEAPSE-GSRRSSSDLI-TLPATTPPCPTKKE---WEGPATSYMTCSAYQKVQD 663
Query: 1016 GDLVFEAGERIEVV-RRDGDWWTGRIGARTGIFPSNYV 1052
++ F AG ++V+ +++ WW R G G PS+Y+
Sbjct: 664 SEISFPAGVEVQVLEKQESGWWYVRFGELEGWAPSHYL 701
Score = 39.1 bits (87), Expect = 0.10
Identities = 17/54 (31%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Query: 1002 EFYIASYPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYVSR 1054
E Y+ PY+S ++ FE G +EV+R++ + WW R + G P++Y+ +
Sbjct: 76 EKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKK 129
Score = 39.1 bits (87), Expect = 0.10
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 4/67 (5%)
Query: 993 EPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVV-RRDGDWWTGRIGARTGIFPSNY 1051
EP SVE E+Y + S G + F G++ EV+ + G WW +IG + G P++Y
Sbjct: 252 EPPSVEV--EYYTIAEFQSCISDG-ISFRGGQKAEVIDKNSGGWWYVQIGEKEGWAPASY 308
Query: 1052 VSREAAP 1058
+ + P
Sbjct: 309 IDKRKKP 315
>U07747-1|AAA19647.1| 847|Homo sapiens serine/threonine protein
kinase protein.
Length = 847
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/77 (38%), Positives = 40/77 (51%), Gaps = 6/77 (7%)
Query: 988 GRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRD----GD--WWTGRIG 1041
GR P + + A + Y S +L G+R+EV+ RD GD WW G++G
Sbjct: 30 GRPEGSPKAAGYANPVWTALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQVG 89
Query: 1042 ARTGIFPSNYVSREAAP 1058
+ GIFPSNYVSR P
Sbjct: 90 GQVGIFPSNYVSRGGGP 106
Score = 52.4 bits (120), Expect = 1e-05
Identities = 24/55 (43%), Positives = 32/55 (58%), Gaps = 4/55 (7%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDR----SQDPAWWQGELRGMVGLFPSNYVTK 1301
AL+ Y DEL+ K D + V R S D WW G++ G VG+FPSNYV++
Sbjct: 48 ALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQVGGQVGIFPSNYVSR 102
Score = 34.3 bits (75), Expect = 2.9
Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 10/58 (17%)
Query: 1164 ALASYTATSPEQLSLMKGQLLVVRKK-----ADSGWWEGELQAKGRNRQVGWFPASYV 1216
AL Y + ++L+L KG + V + D GWW G++ QVG FP++YV
Sbjct: 48 ALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQV-----GGQVGIFPSNYV 100
>L32976-1|AAA59859.1| 847|Homo sapiens protein kinase protein.
Length = 847
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/77 (38%), Positives = 40/77 (51%), Gaps = 6/77 (7%)
Query: 988 GRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRD----GD--WWTGRIG 1041
GR P + + A + Y S +L G+R+EV+ RD GD WW G++G
Sbjct: 30 GRPEGSPKAAGYANPVWTALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQVG 89
Query: 1042 ARTGIFPSNYVSREAAP 1058
+ GIFPSNYVSR P
Sbjct: 90 GQVGIFPSNYVSRGGGP 106
Score = 52.4 bits (120), Expect = 1e-05
Identities = 24/55 (43%), Positives = 32/55 (58%), Gaps = 4/55 (7%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDR----SQDPAWWQGELRGMVGLFPSNYVTK 1301
AL+ Y DEL+ K D + V R S D WW G++ G VG+FPSNYV++
Sbjct: 48 ALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQVGGQVGIFPSNYVSR 102
Score = 34.3 bits (75), Expect = 2.9
Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 10/58 (17%)
Query: 1164 ALASYTATSPEQLSLMKGQLLVVRKK-----ADSGWWEGELQAKGRNRQVGWFPASYV 1216
AL Y + ++L+L KG + V + D GWW G++ QVG FP++YV
Sbjct: 48 ALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQV-----GGQVGIFPSNYV 100
>BC064543-1|AAH64543.1| 847|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 protein.
Length = 847
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/77 (38%), Positives = 40/77 (51%), Gaps = 6/77 (7%)
Query: 988 GRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRD----GD--WWTGRIG 1041
GR P + + A + Y S +L G+R+EV+ RD GD WW G++G
Sbjct: 30 GRPEGSPKAAGYANPVWTALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQVG 89
Query: 1042 ARTGIFPSNYVSREAAP 1058
+ GIFPSNYVSR P
Sbjct: 90 GQVGIFPSNYVSRGGGP 106
Score = 52.4 bits (120), Expect = 1e-05
Identities = 24/55 (43%), Positives = 32/55 (58%), Gaps = 4/55 (7%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDR----SQDPAWWQGELRGMVGLFPSNYVTK 1301
AL+ Y DEL+ K D + V R S D WW G++ G VG+FPSNYV++
Sbjct: 48 ALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQVGGQVGIFPSNYVSR 102
Score = 34.3 bits (75), Expect = 2.9
Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 10/58 (17%)
Query: 1164 ALASYTATSPEQLSLMKGQLLVVRKK-----ADSGWWEGELQAKGRNRQVGWFPASYV 1216
AL Y + ++L+L KG + V + D GWW G++ QVG FP++YV
Sbjct: 48 ALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQV-----GGQVGIFPSNYV 100
>BC011263-1|AAH11263.1| 847|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 protein.
Length = 847
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/77 (38%), Positives = 40/77 (51%), Gaps = 6/77 (7%)
Query: 988 GRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRD----GD--WWTGRIG 1041
GR P + + A + Y S +L G+R+EV+ RD GD WW G++G
Sbjct: 30 GRPEGSPKAAGYANPVWTALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQVG 89
Query: 1042 ARTGIFPSNYVSREAAP 1058
+ GIFPSNYVSR P
Sbjct: 90 GQVGIFPSNYVSRGGGP 106
Score = 52.4 bits (120), Expect = 1e-05
Identities = 24/55 (43%), Positives = 32/55 (58%), Gaps = 4/55 (7%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDR----SQDPAWWQGELRGMVGLFPSNYVTK 1301
AL+ Y DEL+ K D + V R S D WW G++ G VG+FPSNYV++
Sbjct: 48 ALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQVGGQVGIFPSNYVSR 102
Score = 34.3 bits (75), Expect = 2.9
Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 10/58 (17%)
Query: 1164 ALASYTATSPEQLSLMKGQLLVVRKK-----ADSGWWEGELQAKGRNRQVGWFPASYV 1216
AL Y + ++L+L KG + V + D GWW G++ QVG FP++YV
Sbjct: 48 ALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQV-----GGQVGIFPSNYV 100
>AL121834-10|CAI42876.1| 279|Homo sapiens RALBP1 associated Eps
domain containing 1 protein.
Length = 279
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/79 (37%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Query: 20 FRNLGP-VNGNLTGEQAKRFMLQSQLPPPVLGQIWSLADTNADGKLDLKEFSIACKIINL 78
F+ + P +NG + G AK F +S+LP L IW L+D + DG L L EF A ++
Sbjct: 4 FKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVA 63
Query: 79 KLRGLEVPKMLPPSLIASL 97
+ G ++P+ LP SL+ L
Sbjct: 64 RKNGYDLPEKLPESLMPKL 82
Score = 52.4 bits (120), Expect = 1e-05
Identities = 24/64 (37%), Positives = 35/64 (54%)
Query: 382 GTQARSIMLQSRLPQQSLAQIWALADLDADGKLGCEEFVLAMYLCEKATQGEPVPARLPP 441
G+ A+ +S+LP L+ IW L+D D DG L +EF A +L G +P +LP
Sbjct: 17 GSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPE 76
Query: 442 ELIP 445
L+P
Sbjct: 77 SLMP 80
>AK222781-1|BAD96501.1| 847|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 variant protein.
Length = 847
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/77 (38%), Positives = 40/77 (51%), Gaps = 6/77 (7%)
Query: 988 GRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRD----GD--WWTGRIG 1041
GR P + + A + Y S +L G+R+EV+ RD GD WW G++G
Sbjct: 30 GRPEGSPKAAGYANPVWTALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQVG 89
Query: 1042 ARTGIFPSNYVSREAAP 1058
+ GIFPSNYVSR P
Sbjct: 90 GQVGIFPSNYVSRGGGP 106
Score = 52.4 bits (120), Expect = 1e-05
Identities = 24/55 (43%), Positives = 32/55 (58%), Gaps = 4/55 (7%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDR----SQDPAWWQGELRGMVGLFPSNYVTK 1301
AL+ Y DEL+ K D + V R S D WW G++ G VG+FPSNYV++
Sbjct: 48 ALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQVGGQVGIFPSNYVSR 102
Score = 34.3 bits (75), Expect = 2.9
Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 10/58 (17%)
Query: 1164 ALASYTATSPEQLSLMKGQLLVVRKK-----ADSGWWEGELQAKGRNRQVGWFPASYV 1216
AL Y + ++L+L KG + V + D GWW G++ QVG FP++YV
Sbjct: 48 ALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQV-----GGQVGIFPSNYV 100
>AB209655-1|BAD92892.1| 310|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 variant protein.
Length = 310
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/77 (38%), Positives = 40/77 (51%), Gaps = 6/77 (7%)
Query: 988 GRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRD----GD--WWTGRIG 1041
GR P + + A + Y S +L G+R+EV+ RD GD WW G++G
Sbjct: 68 GRPEGSPKAAGYANPVWTALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQVG 127
Query: 1042 ARTGIFPSNYVSREAAP 1058
+ GIFPSNYVSR P
Sbjct: 128 GQVGIFPSNYVSRGGGP 144
Score = 52.4 bits (120), Expect = 1e-05
Identities = 24/55 (43%), Positives = 32/55 (58%), Gaps = 4/55 (7%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDR----SQDPAWWQGELRGMVGLFPSNYVTK 1301
AL+ Y DEL+ K D + V R S D WW G++ G VG+FPSNYV++
Sbjct: 86 ALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQVGGQVGIFPSNYVSR 140
Score = 34.3 bits (75), Expect = 2.9
Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 10/58 (17%)
Query: 1164 ALASYTATSPEQLSLMKGQLLVVRKK-----ADSGWWEGELQAKGRNRQVGWFPASYV 1216
AL Y + ++L+L KG + V + D GWW G++ QVG FP++YV
Sbjct: 86 ALFDYEPSGQDELALRKGDRVEVLSRDAAISGDEGWWAGQV-----GGQVGIFPSNYV 138
>X98411-1|CAA67058.1| 782|Homo sapiens myosin-IF protein.
Length = 782
Score = 58.4 bits (135), Expect = 2e-07
Identities = 26/53 (49%), Positives = 35/53 (66%), Gaps = 3/53 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPA-WWQGELRGMVGLFPSNYVTKL 1302
ALY Y Q+ DELSF +++I + +DP+ WW+G L G GLFP NYV K+
Sbjct: 732 ALYQYVGQDVDELSFNVNEVIEIL--MEDPSGWWKGRLHGQEGLFPGNYVEKI 782
Score = 45.2 bits (102), Expect = 0.002
Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 1/50 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRRD-GDWWTGRIGARTGIFPSNYVSR 1054
A Y Y + +L F E IE++ D WW GR+ + G+FP NYV +
Sbjct: 732 ALYQYVGQDVDELSFNVNEVIEILMEDPSGWWKGRLHGQEGLFPGNYVEK 781
Score = 35.9 bits (79), Expect = 0.95
Identities = 29/90 (32%), Positives = 38/90 (42%), Gaps = 9/90 (10%)
Query: 859 PAEGTWGSSATETV-QTAAPGGEG-PQP----PRWRCVYPFVGRSADELSVQPGDLIVXX 912
P +G G +V Q P G PQP PR R +Y +VG+ DELS ++I
Sbjct: 696 PDQGMAGMQRKRSVGQRPVPVGRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVI--- 752
Query: 913 XXXXXXXXXXXXXXXRGQSGWFPESYVEDL 942
GQ G FP +YVE +
Sbjct: 753 EILMEDPSGWWKGRLHGQEGLFPGNYVEKI 782
Score = 35.5 bits (78), Expect = 1.3
Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 5/69 (7%)
Query: 1149 GRDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQV 1208
GR R +AL Y ++LS +++ + + SGWW+G L Q
Sbjct: 717 GRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVIEILMEDPSGWWKGRLHG-----QE 771
Query: 1209 GWFPASYVK 1217
G FP +YV+
Sbjct: 772 GLFPGNYVE 780
>CR457361-1|CAG33642.1| 323|Homo sapiens SH3YL1 protein.
Length = 323
Score = 58.4 bits (135), Expect = 2e-07
Identities = 24/51 (47%), Positives = 35/51 (68%), Gaps = 3/51 (5%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRRDG---DWWTGRIGARTGIFPSNYVS 1053
A Y + +PGDL F+AG+RI V+ + DWW G++ +TGIFP+NYV+
Sbjct: 271 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 321
Score = 54.4 bits (125), Expect = 3e-06
Identities = 23/54 (42%), Positives = 34/54 (62%), Gaps = 1/54 (1%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPA-WWQGELRGMVGLFPSNYVT 1300
+V ALY + Q +L+F+ D I V ++ WW+G+LRG G+FP+NYVT
Sbjct: 268 EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 321
>BC028071-1|AAH28071.1| 1098|Homo sapiens myosin IF protein.
Length = 1098
Score = 58.4 bits (135), Expect = 2e-07
Identities = 26/53 (49%), Positives = 35/53 (66%), Gaps = 3/53 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPA-WWQGELRGMVGLFPSNYVTKL 1302
ALY Y Q+ DELSF +++I + +DP+ WW+G L G GLFP NYV K+
Sbjct: 1048 ALYQYVGQDVDELSFNVNEVIEIL--MEDPSGWWKGRLHGQEGLFPGNYVEKI 1098
Score = 45.2 bits (102), Expect = 0.002
Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 1/50 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRRD-GDWWTGRIGARTGIFPSNYVSR 1054
A Y Y + +L F E IE++ D WW GR+ + G+FP NYV +
Sbjct: 1048 ALYQYVGQDVDELSFNVNEVIEILMEDPSGWWKGRLHGQEGLFPGNYVEK 1097
Score = 36.3 bits (80), Expect = 0.72
Identities = 28/91 (30%), Positives = 38/91 (41%), Gaps = 10/91 (10%)
Query: 859 PAEGTWGSSATETV-QTAAPGGEGPQP------PRWRCVYPFVGRSADELSVQPGDLIVX 911
P +G G +V Q PG P+P PR R +Y +VG+ DELS ++I
Sbjct: 1011 PDQGMAGMQRKRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVI-- 1068
Query: 912 XXXXXXXXXXXXXXXXRGQSGWFPESYVEDL 942
GQ G FP +YVE +
Sbjct: 1069 -EILMEDPSGWWKGRLHGQEGLFPGNYVEKI 1098
Score = 35.5 bits (78), Expect = 1.3
Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 5/69 (7%)
Query: 1149 GRDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQV 1208
GR R +AL Y ++LS +++ + + SGWW+G L Q
Sbjct: 1033 GRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVIEILMEDPSGWWKGRLHG-----QE 1087
Query: 1209 GWFPASYVK 1217
G FP +YV+
Sbjct: 1088 GLFPGNYVE 1096
>BC008375-1|AAH08375.1| 323|Homo sapiens SH3YL1 protein protein.
Length = 323
Score = 58.4 bits (135), Expect = 2e-07
Identities = 24/51 (47%), Positives = 35/51 (68%), Gaps = 3/51 (5%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRRDG---DWWTGRIGARTGIFPSNYVS 1053
A Y + +PGDL F+AG+RI V+ + DWW G++ +TGIFP+NYV+
Sbjct: 271 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 321
Score = 54.4 bits (125), Expect = 3e-06
Identities = 23/54 (42%), Positives = 34/54 (62%), Gaps = 1/54 (1%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPA-WWQGELRGMVGLFPSNYVT 1300
+V ALY + Q +L+F+ D I V ++ WW+G+LRG G+FP+NYVT
Sbjct: 268 EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 321
>BC008374-1|AAH08374.1| 342|Homo sapiens SH3YL1 protein protein.
Length = 342
Score = 58.4 bits (135), Expect = 2e-07
Identities = 24/51 (47%), Positives = 35/51 (68%), Gaps = 3/51 (5%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRRDG---DWWTGRIGARTGIFPSNYVS 1053
A Y + +PGDL F+AG+RI V+ + DWW G++ +TGIFP+NYV+
Sbjct: 290 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 340
Score = 56.8 bits (131), Expect = 5e-07
Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Query: 1222 SGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPA 1281
S R + P LSS + + +V ALY + Q +L+F+ D I V ++
Sbjct: 261 SNRNEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHF 320
Query: 1282 -WWQGELRGMVGLFPSNYVT 1300
WW+G+LRG G+FP+NYVT
Sbjct: 321 DWWEGKLRGQTGIFPANYVT 340
>AL732423-6|CAI40280.1| 645|Homo sapiens SH3-domain kinase binding
protein 1 protein.
Length = 645
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 6/85 (7%)
Query: 1224 RTSGRTTPVLSSKMDALPTETVI-----DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+T G+ P ++ D+ TE D ++PY AQN DEL+ ++ DI+ + ++
Sbjct: 222 KTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDC 281
Query: 1279 -DPAWWQGELRGMVGLFPSNYVTKL 1302
D WW+GEL G G+FP N+V L
Sbjct: 282 IDVGWWEGELNGRRGVFPDNFVKLL 306
Score = 50.0 bits (114), Expect = 5e-05
Identities = 21/50 (42%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Query: 1253 YPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ Y QN DEL + DII V ++ WW+G L G G+FPSN++ +L
Sbjct: 43 FSYLPQNDDELELKVGDIIEVVGEVEE-GWWEGVLNGKTGMFPSNFIKEL 91
Score = 46.0 bits (104), Expect = 9e-04
Identities = 26/99 (26%), Positives = 47/99 (47%), Gaps = 7/99 (7%)
Query: 1150 RDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVG 1209
R + G R+ Q SY + ++L L G ++ V + + GWWEG L N + G
Sbjct: 27 RTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVL-----NGKTG 81
Query: 1210 WFPASYVKVLQSSGRTSG--RTTPVLSSKMDALPTETVI 1246
FP++++K L G + + S+ + LP +++
Sbjct: 82 MFPSNFIKELSGESDELGISQDEQLSKSRPEGLPPASLL 120
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 977 LGGALPAVV-DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDG-- 1033
+G LPA P + +E S ++ +PY + +L + G+ + ++ +D
Sbjct: 224 IGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCID 283
Query: 1034 -DWWTGRIGARTGIFPSNYV 1052
WW G + R G+FP N+V
Sbjct: 284 VGWWEGELNGRRGVFPDNFV 303
Score = 41.5 bits (93), Expect = 0.019
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 1147 DSGRDSVTGRRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKG 1203
DS + + R K + + + Y A + ++L++ +G ++ + K D GWWEGEL
Sbjct: 236 DSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL---- 291
Query: 1204 RNRQVGWFPASYVKVL 1219
N + G FP ++VK+L
Sbjct: 292 -NGRRGVFPDNFVKLL 306
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 1007 SYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
++ Y +L + G+ IEVV + WW G + +TG+FPSN++
Sbjct: 42 AFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFI 88
>AL732423-4|CAI40277.1| 628|Homo sapiens SH3-domain kinase binding
protein 1 protein.
Length = 628
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 6/85 (7%)
Query: 1224 RTSGRTTPVLSSKMDALPTETVI-----DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+T G+ P ++ D+ TE D ++PY AQN DEL+ ++ DI+ + ++
Sbjct: 205 KTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDC 264
Query: 1279 -DPAWWQGELRGMVGLFPSNYVTKL 1302
D WW+GEL G G+FP N+V L
Sbjct: 265 IDVGWWEGELNGRRGVFPDNFVKLL 289
Score = 50.0 bits (114), Expect = 5e-05
Identities = 21/50 (42%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Query: 1253 YPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ Y QN DEL + DII V ++ WW+G L G G+FPSN++ +L
Sbjct: 70 FSYLPQNDDELELKVGDIIEVVGEVEE-GWWEGVLNGKTGMFPSNFIKEL 118
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 1150 RDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVG 1209
R + G R+ Q SY + ++L L G ++ V + + GWWEG L N + G
Sbjct: 54 RTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVL-----NGKTG 108
Query: 1210 WFPASYVKVLQSSGRTSG 1227
FP++++K L G
Sbjct: 109 MFPSNFIKELSGESDELG 126
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 977 LGGALPAVV-DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDG-- 1033
+G LPA P + +E S ++ +PY + +L + G+ + ++ +D
Sbjct: 207 IGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCID 266
Query: 1034 -DWWTGRIGARTGIFPSNYV 1052
WW G + R G+FP N+V
Sbjct: 267 VGWWEGELNGRRGVFPDNFV 286
Score = 41.5 bits (93), Expect = 0.019
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 1147 DSGRDSVTGRRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKG 1203
DS + + R K + + + Y A + ++L++ +G ++ + K D GWWEGEL
Sbjct: 219 DSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL---- 274
Query: 1204 RNRQVGWFPASYVKVL 1219
N + G FP ++VK+L
Sbjct: 275 -NGRRGVFPDNFVKLL 289
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 1007 SYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
++ Y +L + G+ IEVV + WW G + +TG+FPSN++
Sbjct: 69 AFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFI 115
>AL732327-6|CAI40514.1| 645|Homo sapiens SH3-domain kinase binding
protein 1 protein.
Length = 645
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 6/85 (7%)
Query: 1224 RTSGRTTPVLSSKMDALPTETVI-----DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+T G+ P ++ D+ TE D ++PY AQN DEL+ ++ DI+ + ++
Sbjct: 222 KTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDC 281
Query: 1279 -DPAWWQGELRGMVGLFPSNYVTKL 1302
D WW+GEL G G+FP N+V L
Sbjct: 282 IDVGWWEGELNGRRGVFPDNFVKLL 306
Score = 50.0 bits (114), Expect = 5e-05
Identities = 21/50 (42%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Query: 1253 YPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ Y QN DEL + DII V ++ WW+G L G G+FPSN++ +L
Sbjct: 43 FSYLPQNDDELELKVGDIIEVVGEVEE-GWWEGVLNGKTGMFPSNFIKEL 91
Score = 46.0 bits (104), Expect = 9e-04
Identities = 26/99 (26%), Positives = 47/99 (47%), Gaps = 7/99 (7%)
Query: 1150 RDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVG 1209
R + G R+ Q SY + ++L L G ++ V + + GWWEG L N + G
Sbjct: 27 RTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVL-----NGKTG 81
Query: 1210 WFPASYVKVLQSSGRTSG--RTTPVLSSKMDALPTETVI 1246
FP++++K L G + + S+ + LP +++
Sbjct: 82 MFPSNFIKELSGESDELGISQDEQLSKSRPEGLPPASLL 120
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 977 LGGALPAVV-DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDG-- 1033
+G LPA P + +E S ++ +PY + +L + G+ + ++ +D
Sbjct: 224 IGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCID 283
Query: 1034 -DWWTGRIGARTGIFPSNYV 1052
WW G + R G+FP N+V
Sbjct: 284 VGWWEGELNGRRGVFPDNFV 303
Score = 41.5 bits (93), Expect = 0.019
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 1147 DSGRDSVTGRRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKG 1203
DS + + R K + + + Y A + ++L++ +G ++ + K D GWWEGEL
Sbjct: 236 DSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL---- 291
Query: 1204 RNRQVGWFPASYVKVL 1219
N + G FP ++VK+L
Sbjct: 292 -NGRRGVFPDNFVKLL 306
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 1007 SYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
++ Y +L + G+ IEVV + WW G + +TG+FPSN++
Sbjct: 42 AFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFI 88
>AL732327-3|CAI40511.1| 628|Homo sapiens SH3-domain kinase binding
protein 1 protein.
Length = 628
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 6/85 (7%)
Query: 1224 RTSGRTTPVLSSKMDALPTETVI-----DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+T G+ P ++ D+ TE D ++PY AQN DEL+ ++ DI+ + ++
Sbjct: 205 KTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDC 264
Query: 1279 -DPAWWQGELRGMVGLFPSNYVTKL 1302
D WW+GEL G G+FP N+V L
Sbjct: 265 IDVGWWEGELNGRRGVFPDNFVKLL 289
Score = 50.0 bits (114), Expect = 5e-05
Identities = 21/50 (42%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Query: 1253 YPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ Y QN DEL + DII V ++ WW+G L G G+FPSN++ +L
Sbjct: 70 FSYLPQNDDELELKVGDIIEVVGEVEE-GWWEGVLNGKTGMFPSNFIKEL 118
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 1150 RDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVG 1209
R + G R+ Q SY + ++L L G ++ V + + GWWEG L N + G
Sbjct: 54 RTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVL-----NGKTG 108
Query: 1210 WFPASYVKVLQSSGRTSG 1227
FP++++K L G
Sbjct: 109 MFPSNFIKELSGESDELG 126
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 977 LGGALPAVV-DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDG-- 1033
+G LPA P + +E S ++ +PY + +L + G+ + ++ +D
Sbjct: 207 IGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCID 266
Query: 1034 -DWWTGRIGARTGIFPSNYV 1052
WW G + R G+FP N+V
Sbjct: 267 VGWWEGELNGRRGVFPDNFV 286
Score = 41.5 bits (93), Expect = 0.019
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 1147 DSGRDSVTGRRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKG 1203
DS + + R K + + + Y A + ++L++ +G ++ + K D GWWEGEL
Sbjct: 219 DSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL---- 274
Query: 1204 RNRQVGWFPASYVKVL 1219
N + G FP ++VK+L
Sbjct: 275 -NGRRGVFPDNFVKLL 289
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 1007 SYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
++ Y +L + G+ IEVV + WW G + +TG+FPSN++
Sbjct: 69 AFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFI 115
>AL732325-3|CAI41254.1| 628|Homo sapiens SH3-domain kinase binding
protein 1 protein.
Length = 628
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 6/85 (7%)
Query: 1224 RTSGRTTPVLSSKMDALPTETVI-----DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+T G+ P ++ D+ TE D ++PY AQN DEL+ ++ DI+ + ++
Sbjct: 205 KTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDC 264
Query: 1279 -DPAWWQGELRGMVGLFPSNYVTKL 1302
D WW+GEL G G+FP N+V L
Sbjct: 265 IDVGWWEGELNGRRGVFPDNFVKLL 289
Score = 50.0 bits (114), Expect = 5e-05
Identities = 21/50 (42%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Query: 1253 YPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ Y QN DEL + DII V ++ WW+G L G G+FPSN++ +L
Sbjct: 70 FSYLPQNDDELELKVGDIIEVVGEVEE-GWWEGVLNGKTGMFPSNFIKEL 118
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 1150 RDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVG 1209
R + G R+ Q SY + ++L L G ++ V + + GWWEG L N + G
Sbjct: 54 RTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVL-----NGKTG 108
Query: 1210 WFPASYVKVLQSSGRTSG 1227
FP++++K L G
Sbjct: 109 MFPSNFIKELSGESDELG 126
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 977 LGGALPAVV-DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDG-- 1033
+G LPA P + +E S ++ +PY + +L + G+ + ++ +D
Sbjct: 207 IGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCID 266
Query: 1034 -DWWTGRIGARTGIFPSNYV 1052
WW G + R G+FP N+V
Sbjct: 267 VGWWEGELNGRRGVFPDNFV 286
Score = 41.5 bits (93), Expect = 0.019
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 1147 DSGRDSVTGRRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKG 1203
DS + + R K + + + Y A + ++L++ +G ++ + K D GWWEGEL
Sbjct: 219 DSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL---- 274
Query: 1204 RNRQVGWFPASYVKVL 1219
N + G FP ++VK+L
Sbjct: 275 -NGRRGVFPDNFVKLL 289
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 1007 SYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
++ Y +L + G+ IEVV + WW G + +TG+FPSN++
Sbjct: 69 AFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFI 115
>AK026507-1|BAB15493.1| 323|Homo sapiens protein ( Homo sapiens cDNA:
FLJ22854 fis, clone KAT00983. ).
Length = 323
Score = 58.4 bits (135), Expect = 2e-07
Identities = 24/51 (47%), Positives = 35/51 (68%), Gaps = 3/51 (5%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRRDG---DWWTGRIGARTGIFPSNYVS 1053
A Y + +PGDL F+AG+RI V+ + DWW G++ +TGIFP+NYV+
Sbjct: 271 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 321
Score = 54.4 bits (125), Expect = 3e-06
Identities = 23/54 (42%), Positives = 34/54 (62%), Gaps = 1/54 (1%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPA-WWQGELRGMVGLFPSNYVT 1300
+V ALY + Q +L+F+ D I V ++ WW+G+LRG G+FP+NYVT
Sbjct: 268 EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 321
>AJ310570-1|CAC83948.1| 1098|Homo sapiens Myosin-1F protein.
Length = 1098
Score = 58.4 bits (135), Expect = 2e-07
Identities = 26/53 (49%), Positives = 35/53 (66%), Gaps = 3/53 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPA-WWQGELRGMVGLFPSNYVTKL 1302
ALY Y Q+ DELSF +++I + +DP+ WW+G L G GLFP NYV K+
Sbjct: 1048 ALYQYVGQDVDELSFNVNEVIEIL--MEDPSGWWKGRLHGQEGLFPGNYVEKI 1098
Score = 45.2 bits (102), Expect = 0.002
Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 1/50 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRRD-GDWWTGRIGARTGIFPSNYVSR 1054
A Y Y + +L F E IE++ D WW GR+ + G+FP NYV +
Sbjct: 1048 ALYQYVGQDVDELSFNVNEVIEILMEDPSGWWKGRLHGQEGLFPGNYVEK 1097
Score = 36.3 bits (80), Expect = 0.72
Identities = 28/91 (30%), Positives = 38/91 (41%), Gaps = 10/91 (10%)
Query: 859 PAEGTWGSSATETV-QTAAPGGEGPQP------PRWRCVYPFVGRSADELSVQPGDLIVX 911
P +G G +V Q PG P+P PR R +Y +VG+ DELS ++I
Sbjct: 1011 PDQGMAGMQRKRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVI-- 1068
Query: 912 XXXXXXXXXXXXXXXXRGQSGWFPESYVEDL 942
GQ G FP +YVE +
Sbjct: 1069 -EILMEDPSGWWKGRLHGQEGLFPGNYVEKI 1098
Score = 35.5 bits (78), Expect = 1.3
Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 5/69 (7%)
Query: 1149 GRDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQV 1208
GR R +AL Y ++LS +++ + + SGWW+G L Q
Sbjct: 1033 GRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVIEILMEDPSGWWKGRLHG-----QE 1087
Query: 1209 GWFPASYVK 1217
G FP +YV+
Sbjct: 1088 GLFPGNYVE 1096
>AF542051-1|AAN77231.1| 628|Homo sapiens CD2 binding protein CD2BP3
protein.
Length = 628
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 6/85 (7%)
Query: 1224 RTSGRTTPVLSSKMDALPTETVI-----DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ 1278
+T G+ P ++ D+ TE D ++PY AQN DEL+ ++ DI+ + ++
Sbjct: 205 KTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDC 264
Query: 1279 -DPAWWQGELRGMVGLFPSNYVTKL 1302
D WW+GEL G G+FP N+V L
Sbjct: 265 IDVGWWEGELNGRRGVFPDNFVKLL 289
Score = 50.0 bits (114), Expect = 5e-05
Identities = 21/50 (42%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Query: 1253 YPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
+ Y QN DEL + DII V ++ WW+G L G G+FPSN++ +L
Sbjct: 70 FSYLPQNDDELELKVGDIIEVVGEVEE-GWWEGVLNGKTGMFPSNFIKEL 118
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 1150 RDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVG 1209
R + G R+ Q SY + ++L L G ++ V + + GWWEG L N + G
Sbjct: 54 RTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVL-----NGKTG 108
Query: 1210 WFPASYVKVLQSSGRTSG 1227
FP++++K L G
Sbjct: 109 MFPSNFIKELSGESDELG 126
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 977 LGGALPAVV-DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDG-- 1033
+G LPA P + +E S ++ +PY + +L + G+ + ++ +D
Sbjct: 207 IGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCID 266
Query: 1034 -DWWTGRIGARTGIFPSNYV 1052
WW G + R G+FP N+V
Sbjct: 267 VGWWEGELNGRRGVFPDNFV 286
Score = 41.5 bits (93), Expect = 0.019
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 1147 DSGRDSVTGRRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKG 1203
DS + + R K + + + Y A + ++L++ +G ++ + K D GWWEGEL
Sbjct: 219 DSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL---- 274
Query: 1204 RNRQVGWFPASYVKVL 1219
N + G FP ++VK+L
Sbjct: 275 -NGRRGVFPDNFVKLL 289
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 1007 SYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
++ Y +L + G+ IEVV + WW G + +TG+FPSN++
Sbjct: 69 AFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFI 115
>AC079779-1|AAY14957.1| 342|Homo sapiens unknown protein.
Length = 342
Score = 58.4 bits (135), Expect = 2e-07
Identities = 24/51 (47%), Positives = 35/51 (68%), Gaps = 3/51 (5%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRRDG---DWWTGRIGARTGIFPSNYVS 1053
A Y + +PGDL F+AG+RI V+ + DWW G++ +TGIFP+NYV+
Sbjct: 290 ALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 340
Score = 56.8 bits (131), Expect = 5e-07
Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Query: 1222 SGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPA 1281
S R + P LSS + + +V ALY + Q +L+F+ D I V ++
Sbjct: 261 SNRNEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHF 320
Query: 1282 -WWQGELRGMVGLFPSNYVT 1300
WW+G+LRG G+FP+NYVT
Sbjct: 321 DWWEGKLRGQTGIFPANYVT 340
>AB210037-1|BAE06119.1| 1143|Homo sapiens MYO1F variant protein
protein.
Length = 1143
Score = 58.4 bits (135), Expect = 2e-07
Identities = 26/53 (49%), Positives = 35/53 (66%), Gaps = 3/53 (5%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPA-WWQGELRGMVGLFPSNYVTKL 1302
ALY Y Q+ DELSF +++I + +DP+ WW+G L G GLFP NYV K+
Sbjct: 1093 ALYQYVGQDVDELSFNVNEVIEIL--MEDPSGWWKGRLHGQEGLFPGNYVEKI 1143
Score = 45.2 bits (102), Expect = 0.002
Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 1/50 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRRD-GDWWTGRIGARTGIFPSNYVSR 1054
A Y Y + +L F E IE++ D WW GR+ + G+FP NYV +
Sbjct: 1093 ALYQYVGQDVDELSFNVNEVIEILMEDPSGWWKGRLHGQEGLFPGNYVEK 1142
Score = 36.3 bits (80), Expect = 0.72
Identities = 28/91 (30%), Positives = 38/91 (41%), Gaps = 10/91 (10%)
Query: 859 PAEGTWGSSATETV-QTAAPGGEGPQP------PRWRCVYPFVGRSADELSVQPGDLIVX 911
P +G G +V Q PG P+P PR R +Y +VG+ DELS ++I
Sbjct: 1056 PDQGMAGMQRKRSVGQRPVPGVGRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVI-- 1113
Query: 912 XXXXXXXXXXXXXXXXRGQSGWFPESYVEDL 942
GQ G FP +YVE +
Sbjct: 1114 -EILMEDPSGWWKGRLHGQEGLFPGNYVEKI 1143
Score = 35.5 bits (78), Expect = 1.3
Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 5/69 (7%)
Query: 1149 GRDSVTGRRKHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQV 1208
GR R +AL Y ++LS +++ + + SGWW+G L Q
Sbjct: 1078 GRPKPQPRTHGPRCRALYQYVGQDVDELSFNVNEVIEILMEDPSGWWKGRLHG-----QE 1132
Query: 1209 GWFPASYVK 1217
G FP +YV+
Sbjct: 1133 GLFPGNYVE 1141
>X16663-1|CAA34651.1| 486|Homo sapiens protein ( Human HS1 gene for
heamatopoietic lineage cell specific protein. ).
Length = 486
Score = 58.0 bits (134), Expect = 2e-07
Identities = 26/53 (49%), Positives = 33/53 (62%), Gaps = 1/53 (1%)
Query: 1250 VALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
VALY Y + +DELSF+ DD+I + D WW+G G GLFP+NYV L
Sbjct: 434 VALYDYQGEGSDELSFDPDDVITDIEMV-DEGWWRGRCHGHFGLFPANYVKLL 485
Score = 38.7 bits (86), Expect = 0.14
Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Query: 957 EPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPG 1016
EP+ E + E + +S L G+ G + V++ G +A Y Y
Sbjct: 392 EPEGDYEEVLEPEDSSFSSALAGSSGCPAGAG---AGAVAL---GISAVALYDYQGEGSD 445
Query: 1017 DLVFEAGERI-EVVRRDGDWWTGRIGARTGIFPSNYV 1052
+L F+ + I ++ D WW GR G+FP+NYV
Sbjct: 446 ELSFDPDDVITDIEMVDEGWWRGRCHGHFGLFPANYV 482
Score = 35.5 bits (78), Expect = 1.3
Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 5/57 (8%)
Query: 1164 ALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
AL Y ++LS ++ + D GWW G G FPA+YVK+L+
Sbjct: 435 ALYDYQGEGSDELSFDPDDVITDIEMVDEGWWRGRCHG-----HFGLFPANYVKLLE 486
>U43899-1|AAC50734.1| 540|Homo sapiens STAM protein.
Length = 540
Score = 58.0 bits (134), Expect = 2e-07
Identities = 27/53 (50%), Positives = 36/53 (67%), Gaps = 1/53 (1%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVT 1300
KV A+Y + A +EL+F+ +II V D S DP WW+GE +GLFPSN+VT
Sbjct: 214 KVRAIYDFEAAEDNELTFKAGEIITVLDDS-DPNWWKGETHQGIGLFPSNFVT 265
Score = 46.0 bits (104), Expect = 9e-04
Identities = 32/117 (27%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
Query: 940 EDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVED 999
E A A V + T+ K + E +A+ E + T S + +
Sbjct: 151 EQAKASPALVAKDPGTVANKKEEEDLAKAIELSLKEQRQQSTTLSTLYPSTSSLLTNHQH 210
Query: 1000 DGEFYIASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYVSRE 1055
+G A Y + ++E +L F+AGE I V+ D +WW G G+FPSN+V+ +
Sbjct: 211 EGRKVRAIYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGIGLFPSNFVTAD 267
Score = 36.3 bits (80), Expect = 0.72
Identities = 15/55 (27%), Positives = 31/55 (56%), Gaps = 5/55 (9%)
Query: 1162 VQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
V+A+ + A +L+ G+++ V +D WW+GE ++ +G FP+++V
Sbjct: 215 VRAIYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGE-----THQGIGLFPSNFV 264
>DQ307286-1|ABC25188.1| 269|Homo sapiens plenty of SH3s-2 protein.
Length = 269
Score = 58.0 bits (134), Expect = 2e-07
Identities = 45/137 (32%), Positives = 64/137 (46%), Gaps = 22/137 (16%)
Query: 1163 QALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSS 1222
+AL SY P L KG ++V+R+K D W+ GEL G+ PASY++ +Q
Sbjct: 155 KALYSYEGKEPGDLKFNKGDIIVLRRKVDEQWYHGELHG-----TQGFLPASYIQCIQ-- 207
Query: 1223 GRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAW 1282
P + AL + DK Q+ D L+F KD+I+ V R D W
Sbjct: 208 ------PLPHAPPQGKALYDFEMKDK--------DQDKDCLTFTKDEILTVL-RRVDENW 252
Query: 1283 WQGELRGMVGLFPSNYV 1299
+G L +G+FP YV
Sbjct: 253 AEGMLGDKIGIFPLLYV 269
Score = 51.2 bits (117), Expect = 2e-05
Identities = 32/100 (32%), Positives = 47/100 (47%), Gaps = 2/100 (2%)
Query: 1201 AKGRNRQVGWFPASYVKVLQSSGRTSGRTTPVLSSKM-DALPTETVIDKVVALYPYTAQN 1259
A G G P S V + ++G T+G + +S+ A ++ ALY Y +
Sbjct: 105 AGGGGGAAGSTPGSPVFLSAAAGSTAGSLRELATSRTAPAAKNPCLLPYGKALYSYEGKE 164
Query: 1260 ADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+L F K DII V R D W+ GEL G G P++Y+
Sbjct: 165 PGDLKFNKGDII-VLRRKVDEQWYHGELHGTQGFLPASYI 203
Score = 40.7 bits (91), Expect = 0.034
Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
A Y Y EPGDL F G+ I + R+ D W+ G + G P++Y+
Sbjct: 156 ALYSYEGKEPGDLKFNKGDIIVLRRKVDEQWYHGELHGTQGFLPASYI 203
>CR456794-1|CAG33075.1| 486|Homo sapiens HCLS1 protein.
Length = 486
Score = 58.0 bits (134), Expect = 2e-07
Identities = 26/53 (49%), Positives = 33/53 (62%), Gaps = 1/53 (1%)
Query: 1250 VALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
VALY Y + +DELSF+ DD+I + D WW+G G GLFP+NYV L
Sbjct: 434 VALYDYQGEGSDELSFDPDDVITDIEMV-DEGWWRGRCHGHFGLFPANYVKLL 485
Score = 38.7 bits (86), Expect = 0.14
Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Query: 957 EPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPG 1016
EP+ E + E + +S L G+ G + V++ G +A Y Y
Sbjct: 392 EPEGDYEEVLEPEDSSFSSALAGSSGCPAGAG---AGAVAL---GISAVALYDYQGEGSD 445
Query: 1017 DLVFEAGERI-EVVRRDGDWWTGRIGARTGIFPSNYV 1052
+L F+ + I ++ D WW GR G+FP+NYV
Sbjct: 446 ELSFDPDDVITDIEMVDEGWWRGRCHGHFGLFPANYV 482
Score = 34.7 bits (76), Expect = 2.2
Identities = 18/56 (32%), Positives = 25/56 (44%), Gaps = 5/56 (8%)
Query: 1164 ALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVL 1219
AL Y ++LS ++ + D GWW G G FPA+YVK+L
Sbjct: 435 ALYDYQGEGSDELSFDPDDVITDIEMVDEGWWRGRCHG-----HFGLFPANYVKLL 485
>BT006824-1|AAP35470.1| 486|Homo sapiens hematopoietic cell-specific
Lyn substrate 1 protein.
Length = 486
Score = 58.0 bits (134), Expect = 2e-07
Identities = 26/53 (49%), Positives = 33/53 (62%), Gaps = 1/53 (1%)
Query: 1250 VALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
VALY Y + +DELSF+ DD+I + D WW+G G GLFP+NYV L
Sbjct: 434 VALYDYQGEGSDELSFDPDDVITDIEMV-DEGWWRGRCHGHFGLFPANYVKLL 485
Score = 38.7 bits (86), Expect = 0.14
Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Query: 957 EPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPG 1016
EP+ E + E + +S L G+ G + V++ G +A Y Y
Sbjct: 392 EPEGDYEEVLEPEDSSFSSALAGSSGCPAGAG---AGAVAL---GISAVALYDYQGEGSD 445
Query: 1017 DLVFEAGERI-EVVRRDGDWWTGRIGARTGIFPSNYV 1052
+L F+ + I ++ D WW GR G+FP+NYV
Sbjct: 446 ELSFDPDDVITDIEMVDEGWWRGRCHGHFGLFPANYV 482
Score = 35.5 bits (78), Expect = 1.3
Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 5/57 (8%)
Query: 1164 ALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
AL Y ++LS ++ + D GWW G G FPA+YVK+L+
Sbjct: 435 ALYDYQGEGSDELSFDPDDVITDIEMVDEGWWRGRCHG-----HFGLFPANYVKLLE 486
>BC109231-1|AAI09232.1| 269|Homo sapiens STAC2 protein protein.
Length = 269
Score = 58.0 bits (134), Expect = 2e-07
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 3/94 (3%)
Query: 964 GIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFY--IASYPYSSSEPGDLVFE 1021
G + P A ++ G P PG+ + + +D G Y +A Y + E DL +
Sbjct: 113 GDSASPVFTAPAESEGPGPEEKSPGQQLPKATLRKDVGPMYSYVALYKFLPQENNDLALQ 172
Query: 1022 AGERIEVVRRDG-DWWTGRIGARTGIFPSNYVSR 1054
G+RI +V DWW G+IG R G FP+N+V R
Sbjct: 173 PGDRIMLVDDSNEDWWKGKIGDRVGFFPANFVQR 206
Score = 45.2 bits (102), Expect = 0.002
Identities = 19/53 (35%), Positives = 33/53 (62%), Gaps = 1/53 (1%)
Query: 1250 VALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
VALY + Q ++L+ + D I + D S + WW+G++ VG FP+N+V ++
Sbjct: 156 VALYKFLPQENNDLALQPGDRIMLVDDSNED-WWKGKIGDRVGFFPANFVQRV 207
>BC030586-1|AAH30586.1| 403|Homo sapiens STAM protein protein.
Length = 403
Score = 58.0 bits (134), Expect = 2e-07
Identities = 27/53 (50%), Positives = 36/53 (67%), Gaps = 1/53 (1%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVT 1300
KV A+Y + A +EL+F+ +II V D S DP WW+GE +GLFPSN+VT
Sbjct: 214 KVRAIYDFEAAEDNELTFKAGEIITVLDDS-DPNWWKGETHQGIGLFPSNFVT 265
Score = 45.6 bits (103), Expect = 0.001
Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Query: 940 EDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVED 999
E A A V + T+ K + E +A+ E + T S + +
Sbjct: 151 EQAKASPALVAKDPGTVANKKEEEDLAKAIELSLKEQRQQSTTLSTLYPSTSSLLTNHQH 210
Query: 1000 DGEFYIASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYVS 1053
+G A Y + ++E +L F+AGE I V+ D +WW G G+FPSN+V+
Sbjct: 211 EGRKVRAIYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGIGLFPSNFVT 265
Score = 36.7 bits (81), Expect = 0.55
Identities = 19/84 (22%), Positives = 40/84 (47%), Gaps = 5/84 (5%)
Query: 1162 VQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQS 1221
V+A+ + A +L+ G+++ V +D WW+GE ++ +G FP+++V +
Sbjct: 215 VRAIYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGE-----THQGIGLFPSNFVTAYLT 269
Query: 1222 SGRTSGRTTPVLSSKMDALPTETV 1245
+ +T D + ET+
Sbjct: 270 AEPEMIKTEKKTVQFSDDVQVETI 293
>BC016758-1|AAH16758.1| 486|Homo sapiens hematopoietic cell-specific
Lyn substrate 1 protein.
Length = 486
Score = 58.0 bits (134), Expect = 2e-07
Identities = 26/53 (49%), Positives = 33/53 (62%), Gaps = 1/53 (1%)
Query: 1250 VALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
VALY Y + +DELSF+ DD+I + D WW+G G GLFP+NYV L
Sbjct: 434 VALYDYQGEGSDELSFDPDDVITDIEMV-DEGWWRGRCHGHFGLFPANYVKLL 485
Score = 38.7 bits (86), Expect = 0.14
Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Query: 957 EPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPG 1016
EP+ E + E + +S L G+ G + V++ G +A Y Y
Sbjct: 392 EPEGDYEEVLEPEDSSFSSALAGSSGCPAGAG---AGAVAL---GISAVALYDYQGEGSD 445
Query: 1017 DLVFEAGERI-EVVRRDGDWWTGRIGARTGIFPSNYV 1052
+L F+ + I ++ D WW GR G+FP+NYV
Sbjct: 446 ELSFDPDDVITDIEMVDEGWWRGRCHGHFGLFPANYV 482
Score = 35.5 bits (78), Expect = 1.3
Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 5/57 (8%)
Query: 1164 ALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
AL Y ++LS ++ + D GWW G G FPA+YVK+L+
Sbjct: 435 ALYDYQGEGSDELSFDPDDVITDIEMVDEGWWRGRCHG-----HFGLFPANYVKLLE 486
>AK131500-1|BAD18644.1| 411|Homo sapiens protein ( Homo sapiens cDNA
FLJ16708 fis, clone UTERU2008040, weakly similar to Mus
musculus mRNA for stac. ).
Length = 411
Score = 58.0 bits (134), Expect = 2e-07
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 3/94 (3%)
Query: 964 GIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFY--IASYPYSSSEPGDLVFE 1021
G + P A ++ G P PG+ + + +D G Y +A Y + E DL +
Sbjct: 255 GDSASPVFTAPAESEGPGPEEKSPGQQLPKATLRKDVGPMYSYVALYKFLPQENNDLALQ 314
Query: 1022 AGERIEVVRRDG-DWWTGRIGARTGIFPSNYVSR 1054
G+RI +V DWW G+IG R G FP+N+V R
Sbjct: 315 PGDRIMLVDDSNEDWWKGKIGDRVGFFPANFVQR 348
Score = 45.2 bits (102), Expect = 0.002
Identities = 19/53 (35%), Positives = 33/53 (62%), Gaps = 1/53 (1%)
Query: 1250 VALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
VALY + Q ++L+ + D I + D S + WW+G++ VG FP+N+V ++
Sbjct: 298 VALYKFLPQENNDLALQPGDRIMLVDDSNED-WWKGKIGDRVGFFPANFVQRV 349
>AJ608762-1|CAE75539.1| 411|Homo sapiens 24b2/STAC2 protein protein.
Length = 411
Score = 58.0 bits (134), Expect = 2e-07
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 3/94 (3%)
Query: 964 GIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFY--IASYPYSSSEPGDLVFE 1021
G + P A ++ G P PG+ + + +D G Y +A Y + E DL +
Sbjct: 255 GDSASPVFTAPAESEGPGPEEKSPGQQLPKATLRKDVGPMYSYVALYKFLPQENNDLALQ 314
Query: 1022 AGERIEVVRRDG-DWWTGRIGARTGIFPSNYVSR 1054
G+RI +V DWW G+IG R G FP+N+V R
Sbjct: 315 PGDRIMLVDDSNEDWWKGKIGDRVGFFPANFVQR 348
Score = 45.2 bits (102), Expect = 0.002
Identities = 19/53 (35%), Positives = 33/53 (62%), Gaps = 1/53 (1%)
Query: 1250 VALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
VALY + Q ++L+ + D I + D S + WW+G++ VG FP+N+V ++
Sbjct: 298 VALYKFLPQENNDLALQPGDRIMLVDDSNED-WWKGKIGDRVGFFPANFVQRV 349
>U31089-1|AAA75446.1| 390|Homo sapiens Abl binding protein 3 protein.
Length = 390
Score = 57.6 bits (133), Expect = 3e-07
Identities = 25/59 (42%), Positives = 39/59 (66%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
++KVVA+Y YT DELSF++ II V ++ D W++G + G+ GL P NYV +++
Sbjct: 330 LEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDD-GWYEGVMNGVTGLSPGNYVESIMH 387
Score = 39.9 bits (89), Expect = 0.059
Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Query: 986 DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGART 1044
DP P + E +A Y Y+ + +L F+ G I V++++ D W+ G + T
Sbjct: 315 DPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVT 374
Query: 1045 GIFPSNYV 1052
G+ P NYV
Sbjct: 375 GLSPGNYV 382
Score = 39.5 bits (88), Expect = 0.077
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS +G ++ V KK D GW+EG + N G P +YV+
Sbjct: 331 EKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVM-----NGVTGLSPGNYVE 383
>AL732423-5|CAI40278.1| 427|Homo sapiens SH3-domain kinase binding
protein 1 protein.
Length = 427
Score = 57.6 bits (133), Expect = 3e-07
Identities = 30/84 (35%), Positives = 46/84 (54%), Gaps = 6/84 (7%)
Query: 1225 TSGRTTPVLSSKMDALPTETVI-----DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ- 1278
T G+ P ++ D+ TE D ++PY AQN DEL+ ++ DI+ + ++
Sbjct: 5 TIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCI 64
Query: 1279 DPAWWQGELRGMVGLFPSNYVTKL 1302
D WW+GEL G G+FP N+V L
Sbjct: 65 DVGWWEGELNGRRGVFPDNFVKLL 88
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 977 LGGALPAVV-DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDG-- 1033
+G LPA P + +E S ++ +PY + +L + G+ + ++ +D
Sbjct: 6 IGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCID 65
Query: 1034 -DWWTGRIGARTGIFPSNYV 1052
WW G + R G+FP N+V
Sbjct: 66 VGWWEGELNGRRGVFPDNFV 85
Score = 41.5 bits (93), Expect = 0.019
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 1147 DSGRDSVTGRRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKG 1203
DS + + R K + + + Y A + ++L++ +G ++ + K D GWWEGEL
Sbjct: 18 DSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL---- 73
Query: 1204 RNRQVGWFPASYVKVL 1219
N + G FP ++VK+L
Sbjct: 74 -NGRRGVFPDNFVKLL 88
>AL732327-4|CAI40512.1| 427|Homo sapiens SH3-domain kinase binding
protein 1 protein.
Length = 427
Score = 57.6 bits (133), Expect = 3e-07
Identities = 30/84 (35%), Positives = 46/84 (54%), Gaps = 6/84 (7%)
Query: 1225 TSGRTTPVLSSKMDALPTETVI-----DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ- 1278
T G+ P ++ D+ TE D ++PY AQN DEL+ ++ DI+ + ++
Sbjct: 5 TIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCI 64
Query: 1279 DPAWWQGELRGMVGLFPSNYVTKL 1302
D WW+GEL G G+FP N+V L
Sbjct: 65 DVGWWEGELNGRRGVFPDNFVKLL 88
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 977 LGGALPAVV-DPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDG-- 1033
+G LPA P + +E S ++ +PY + +L + G+ + ++ +D
Sbjct: 6 IGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCID 65
Query: 1034 -DWWTGRIGARTGIFPSNYV 1052
WW G + R G+FP N+V
Sbjct: 66 VGWWEGELNGRRGVFPDNFV 85
Score = 41.5 bits (93), Expect = 0.019
Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 1147 DSGRDSVTGRRKH-EIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKG 1203
DS + + R K + + + Y A + ++L++ +G ++ + K D GWWEGEL
Sbjct: 18 DSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL---- 73
Query: 1204 RNRQVGWFPASYVKVL 1219
N + G FP ++VK+L
Sbjct: 74 -NGRRGVFPDNFVKLL 88
>U63717-1|AAB06396.1| 214|Homo sapiens osteoclast stimulating factor
protein.
Length = 214
Score = 57.2 bits (132), Expect = 4e-07
Identities = 26/51 (50%), Positives = 33/51 (64%), Gaps = 1/51 (1%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
ALY + + DEL FE+ DII +TD S D WW+G +G GL PSNYV +
Sbjct: 19 ALYTFEPRTPDELYFEEGDIIYITDMS-DTNWWKGTSKGRTGLIPSNYVAE 68
Score = 46.8 bits (106), Expect = 5e-04
Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVV-RRDGDWWTGRIGARTGIFPSNYVSREA 1056
A Y + P +L FE G+ I + D +WW G RTG+ PSNYV+ +A
Sbjct: 19 ALYTFEPRTPDELYFEEGDIIYITDMSDTNWWKGTSKGRTGLIPSNYVAEQA 70
Score = 37.1 bits (82), Expect = 0.41
Identities = 16/57 (28%), Positives = 34/57 (59%), Gaps = 5/57 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
++ +AL ++ +P++L +G ++ + +D+ WW+G +KGR G P++YV
Sbjct: 15 KVFRALYTFEPRTPDELYFEEGDIIYITDMSDTNWWKG--TSKGR---TGLIPSNYV 66
>M98343-1|AAA58455.1| 550|Homo sapiens amplaxin protein.
Length = 550
Score = 57.2 bits (132), Expect = 4e-07
Identities = 26/50 (52%), Positives = 32/50 (64%), Gaps = 1/50 (2%)
Query: 1250 VALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
VALY Y A DE+SF+ DDII + D WW+G +G GLFP+NYV
Sbjct: 498 VALYDYQAAGDDEISFDPDDIITNIEMIDD-GWWRGVCKGRYGLFPANYV 546
Score = 38.3 bits (85), Expect = 0.18
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 10/105 (9%)
Query: 957 EPKTQLEGIAEVPEQEATSDLGGALPAVVD----PGRTVSEPVSVE----DDGEFYIASY 1008
EP +E A+ E + L A AV + PG +E + + D G +A Y
Sbjct: 443 EPVYSMEA-ADYREASSQQGLAYATEAVYESAEAPGHYPAEDSTYDEYENDLGYTAVALY 501
Query: 1009 PYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
Y ++ ++ F+ + I + D WW G R G+FP+NYV
Sbjct: 502 DYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYV 546
Score = 36.3 bits (80), Expect = 0.72
Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 5/57 (8%)
Query: 1164 ALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
AL Y A +++S ++ + D GWW G KGR G FPA+YV++ Q
Sbjct: 499 ALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRG--VCKGR---YGLFPANYVELRQ 550
>M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein.
Length = 491
Score = 57.2 bits (132), Expect = 4e-07
Identities = 22/59 (37%), Positives = 36/59 (61%), Gaps = 2/59 (3%)
Query: 998 EDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGR--IGARTGIFPSNYVSR 1054
E+ G+ +A YPY P DL F+ GE+++V+ G+WW + + + G PSNYV++
Sbjct: 41 EEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSNYVAK 99
Score = 46.4 bits (105), Expect = 7e-04
Identities = 25/58 (43%), Positives = 34/58 (58%), Gaps = 4/58 (6%)
Query: 1247 DKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGE--LRGMVGLFPSNYVTKL 1302
D VVALYPY + D+LSF+K + + V + + WW+ + L G PSNYV KL
Sbjct: 45 DIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGE--WWKAKSLLTKKEGFIPSNYVAKL 100
>M16038-1|AAA59540.1| 512|Homo sapiens LYN protein.
Length = 512
Score = 57.2 bits (132), Expect = 4e-07
Identities = 22/59 (37%), Positives = 36/59 (61%), Gaps = 2/59 (3%)
Query: 998 EDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGR--IGARTGIFPSNYVSR 1054
E+ G+ +A YPY P DL F+ GE+++V+ G+WW + + + G PSNYV++
Sbjct: 62 EEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSNYVAK 120
Score = 46.4 bits (105), Expect = 7e-04
Identities = 25/58 (43%), Positives = 34/58 (58%), Gaps = 4/58 (6%)
Query: 1247 DKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGE--LRGMVGLFPSNYVTKL 1302
D VVALYPY + D+LSF+K + + V + + WW+ + L G PSNYV KL
Sbjct: 66 DIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGE--WWKAKSLLTKKEGFIPSNYVAKL 121
>D25304-1|BAA04985.1| 773|Homo sapiens KIAA0006 protein.
Length = 773
Score = 57.2 bits (132), Expect = 4e-07
Identities = 27/73 (36%), Positives = 46/73 (63%), Gaps = 6/73 (8%)
Query: 1153 VTGRRKHE-IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWF 1211
+T H+ IV+A ++ T+ ++LS+ KG ++ V + + GWWEG L N + GWF
Sbjct: 152 MTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTL-----NGRTGWF 206
Query: 1212 PASYVKVLQSSGR 1224
P++YV+ ++SS R
Sbjct: 207 PSNYVREIKSSER 219
Score = 52.8 bits (121), Expect = 8e-06
Identities = 26/54 (48%), Positives = 33/54 (61%), Gaps = 1/54 (1%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
V A + + N DELS K DII VT R ++ WW+G L G G FPSNYV ++
Sbjct: 162 VKARFNFKQTNEDELSVCKGDIIYVT-RVEEGGWWEGTLNGRTGWFPSNYVREI 214
Score = 44.4 bits (100), Expect = 0.003
Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 4/78 (5%)
Query: 979 GALPAVVDPGRTVSEPVSVEDDGEFYI---ASYPYSSSEPGDLVFEAGERIEVVR-RDGD 1034
GA+ + V + S+ V + ++G + A + + + +L G+ I V R +G
Sbjct: 134 GAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGG 193
Query: 1035 WWTGRIGARTGIFPSNYV 1052
WW G + RTG FPSNYV
Sbjct: 194 WWEGTLNGRTGWFPSNYV 211
>DQ109556-1|AAZ99795.1| 911|Homo sapiens adaptor protein HOFI
protein.
Length = 911
Score = 57.2 bits (132), Expect = 4e-07
Identities = 35/137 (25%), Positives = 68/137 (49%), Gaps = 19/137 (13%)
Query: 1165 LASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGR 1224
+A+Y ++SL GQ++ + +K +SGWW + GW PA+ ++ G+
Sbjct: 160 VANYQKQESSEISLSVGQVVDIIEKNESGWW-----FVSTAEEQGWVPATCLE-----GQ 209
Query: 1225 TSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQ 1284
+ + P E +K +YPYTA++ DE++ E+ ++ V ++ + WW+
Sbjct: 210 DG------VQDEFSLQPEEE--EKYTVIYPYTARDQDEMNLERGAVVEVIQKNLE-GWWK 260
Query: 1285 GELRGMVGLFPSNYVTK 1301
+G G P++Y+ K
Sbjct: 261 IRYQGKEGWAPASYLKK 277
Score = 41.1 bits (92), Expect = 0.025
Identities = 22/87 (25%), Positives = 49/87 (56%), Gaps = 3/87 (3%)
Query: 973 ATSDLGGALPAVVDPGRT-VSEPVSVE-DDGEFYIASYPYSSSEPGDLVFEAGERIEVVR 1030
+T++ G +PA G+ V + S++ ++ E Y YPY++ + ++ E G +EV++
Sbjct: 193 STAEEQGWVPATCLEGQDGVQDEFSLQPEEEEKYTVIYPYTARDQDEMNLERGAVVEVIQ 252
Query: 1031 RDGD-WWTGRIGARTGIFPSNYVSREA 1056
++ + WW R + G P++Y+ + +
Sbjct: 253 KNLEGWWKIRYQGKEGWAPASYLKKNS 279
Score = 33.9 bits (74), Expect = 3.8
Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 2/60 (3%)
Query: 1158 KHEIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
K + A+A + + S +G + VR+K SGWW ++ G GW P++Y++
Sbjct: 851 KDSLYVAVADFEGDK-DTSSFQEGTVFEVREKNSSGWWFCQV-LSGAPSWEGWIPSNYLR 908
Score = 33.5 bits (73), Expect = 5.1
Identities = 14/62 (22%), Positives = 35/62 (56%), Gaps = 2/62 (3%)
Query: 994 PVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRD-GDWWTGRIGARTGIFPSNYV 1052
P+ + + E+Y + + ++ P + F+AG ++EV+ ++ WW +I + G P+ ++
Sbjct: 364 PIPPQVEEEYYTIA-EFQTTIPDGISFQAGLKVEVIEKNLSGWWYIQIEDKEGWAPATFI 422
Query: 1053 SR 1054
+
Sbjct: 423 DK 424
>BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein.
Length = 512
Score = 57.2 bits (132), Expect = 4e-07
Identities = 22/59 (37%), Positives = 36/59 (61%), Gaps = 2/59 (3%)
Query: 998 EDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGR--IGARTGIFPSNYVSR 1054
E+ G+ +A YPY P DL F+ GE+++V+ G+WW + + + G PSNYV++
Sbjct: 62 EEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSNYVAK 120
Score = 46.4 bits (105), Expect = 7e-04
Identities = 25/58 (43%), Positives = 34/58 (58%), Gaps = 4/58 (6%)
Query: 1247 DKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGE--LRGMVGLFPSNYVTKL 1302
D VVALYPY + D+LSF+K + + V + + WW+ + L G PSNYV KL
Sbjct: 66 DIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGE--WWKAKSLLTKKEGFIPSNYVAKL 121
>BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein.
Length = 512
Score = 57.2 bits (132), Expect = 4e-07
Identities = 22/59 (37%), Positives = 36/59 (61%), Gaps = 2/59 (3%)
Query: 998 EDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGR--IGARTGIFPSNYVSR 1054
E+ G+ +A YPY P DL F+ GE+++V+ G+WW + + + G PSNYV++
Sbjct: 62 EEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSNYVAK 120
Score = 46.4 bits (105), Expect = 7e-04
Identities = 25/58 (43%), Positives = 34/58 (58%), Gaps = 4/58 (6%)
Query: 1247 DKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGE--LRGMVGLFPSNYVTKL 1302
D VVALYPY + D+LSF+K + + V + + WW+ + L G PSNYV KL
Sbjct: 66 DIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGE--WWKAKSLLTKKEGFIPSNYVAKL 121
>BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral related oncogene homolog protein.
Length = 512
Score = 57.2 bits (132), Expect = 4e-07
Identities = 22/59 (37%), Positives = 36/59 (61%), Gaps = 2/59 (3%)
Query: 998 EDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGR--IGARTGIFPSNYVSR 1054
E+ G+ +A YPY P DL F+ GE+++V+ G+WW + + + G PSNYV++
Sbjct: 62 EEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSNYVAK 120
Score = 46.4 bits (105), Expect = 7e-04
Identities = 25/58 (43%), Positives = 34/58 (58%), Gaps = 4/58 (6%)
Query: 1247 DKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGE--LRGMVGLFPSNYVTKL 1302
D VVALYPY + D+LSF+K + + V + + WW+ + L G PSNYV KL
Sbjct: 66 DIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGE--WWKAKSLLTKKEGFIPSNYVAKL 121
>BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral related oncogene homolog protein.
Length = 512
Score = 57.2 bits (132), Expect = 4e-07
Identities = 22/59 (37%), Positives = 36/59 (61%), Gaps = 2/59 (3%)
Query: 998 EDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGR--IGARTGIFPSNYVSR 1054
E+ G+ +A YPY P DL F+ GE+++V+ G+WW + + + G PSNYV++
Sbjct: 62 EEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSNYVAK 120
Score = 46.4 bits (105), Expect = 7e-04
Identities = 25/58 (43%), Positives = 34/58 (58%), Gaps = 4/58 (6%)
Query: 1247 DKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGE--LRGMVGLFPSNYVTKL 1302
D VVALYPY + D+LSF+K + + V + + WW+ + L G PSNYV KL
Sbjct: 66 DIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGE--WWKAKSLLTKKEGFIPSNYVAKL 121
>BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein.
Length = 582
Score = 57.2 bits (132), Expect = 4e-07
Identities = 22/59 (37%), Positives = 36/59 (61%), Gaps = 2/59 (3%)
Query: 998 EDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGR--IGARTGIFPSNYVSR 1054
E+ G+ +A YPY P DL F+ GE+++V+ G+WW + + + G PSNYV++
Sbjct: 132 EEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSNYVAK 190
Score = 46.4 bits (105), Expect = 7e-04
Identities = 25/58 (43%), Positives = 34/58 (58%), Gaps = 4/58 (6%)
Query: 1247 DKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGE--LRGMVGLFPSNYVTKL 1302
D VVALYPY + D+LSF+K + + V + + WW+ + L G PSNYV KL
Sbjct: 136 DIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGE--WWKAKSLLTKKEGFIPSNYVAKL 191
>BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein.
Length = 582
Score = 57.2 bits (132), Expect = 4e-07
Identities = 22/59 (37%), Positives = 36/59 (61%), Gaps = 2/59 (3%)
Query: 998 EDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGR--IGARTGIFPSNYVSR 1054
E+ G+ +A YPY P DL F+ GE+++V+ G+WW + + + G PSNYV++
Sbjct: 132 EEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSNYVAK 190
Score = 46.4 bits (105), Expect = 7e-04
Identities = 25/58 (43%), Positives = 34/58 (58%), Gaps = 4/58 (6%)
Query: 1247 DKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGE--LRGMVGLFPSNYVTKL 1302
D VVALYPY + D+LSF+K + + V + + WW+ + L G PSNYV KL
Sbjct: 136 DIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGE--WWKAKSLLTKKEGFIPSNYVAKL 191
>BC043505-1|AAH43505.1| 538|Homo sapiens ARHGEF6 protein protein.
Length = 538
Score = 57.2 bits (132), Expect = 4e-07
Identities = 27/73 (36%), Positives = 46/73 (63%), Gaps = 6/73 (8%)
Query: 1153 VTGRRKHE-IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWF 1211
+T H+ IV+A ++ T+ ++LS+ KG ++ V + + GWWEG L N + GWF
Sbjct: 1 MTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTL-----NGRTGWF 55
Query: 1212 PASYVKVLQSSGR 1224
P++YV+ ++SS R
Sbjct: 56 PSNYVREIKSSER 68
Score = 52.8 bits (121), Expect = 8e-06
Identities = 26/54 (48%), Positives = 33/54 (61%), Gaps = 1/54 (1%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
V A + + N DELS K DII VT R ++ WW+G L G G FPSNYV ++
Sbjct: 11 VKARFNFKQTNEDELSVCKGDIIYVT-RVEEGGWWEGTLNGRTGWFPSNYVREI 63
Score = 40.7 bits (91), Expect = 0.034
Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYV 1052
A + + + +L G+ I V R +G WW G + RTG FPSNYV
Sbjct: 13 ARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYV 60
>BC039856-1|AAH39856.1| 776|Homo sapiens Rac/Cdc42 guanine nucleotide
exchange factor (GEF) 6 protein.
Length = 776
Score = 57.2 bits (132), Expect = 4e-07
Identities = 27/73 (36%), Positives = 46/73 (63%), Gaps = 6/73 (8%)
Query: 1153 VTGRRKHE-IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWF 1211
+T H+ IV+A ++ T+ ++LS+ KG ++ V + + GWWEG L N + GWF
Sbjct: 155 MTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTL-----NGRTGWF 209
Query: 1212 PASYVKVLQSSGR 1224
P++YV+ ++SS R
Sbjct: 210 PSNYVREIKSSER 222
Score = 52.8 bits (121), Expect = 8e-06
Identities = 26/54 (48%), Positives = 33/54 (61%), Gaps = 1/54 (1%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
V A + + N DELS K DII VT R ++ WW+G L G G FPSNYV ++
Sbjct: 165 VKARFNFKQTNEDELSVCKGDIIYVT-RVEEGGWWEGTLNGRTGWFPSNYVREI 217
Score = 44.4 bits (100), Expect = 0.003
Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 4/78 (5%)
Query: 979 GALPAVVDPGRTVSEPVSVEDDGEFYI---ASYPYSSSEPGDLVFEAGERIEVVR-RDGD 1034
GA+ + V + S+ V + ++G + A + + + +L G+ I V R +G
Sbjct: 137 GAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGG 196
Query: 1035 WWTGRIGARTGIFPSNYV 1052
WW G + RTG FPSNYV
Sbjct: 197 WWEGTLNGRTGWFPSNYV 214
>BC008799-1|AAH08799.1| 513|Homo sapiens cortactin protein.
Length = 513
Score = 57.2 bits (132), Expect = 4e-07
Identities = 26/50 (52%), Positives = 32/50 (64%), Gaps = 1/50 (2%)
Query: 1250 VALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
VALY Y A DE+SF+ DDII + D WW+G +G GLFP+NYV
Sbjct: 461 VALYDYQAAGDDEISFDPDDIITNIEMIDD-GWWRGVCKGRYGLFPANYV 509
Score = 37.9 bits (84), Expect = 0.24
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 10/105 (9%)
Query: 957 EPKTQLEGIAEVPEQEATSDLGGALPAVVD----PGRTVSEPVSVE----DDGEFYIASY 1008
EP +E A+ E + L A AV + PG +E + + D G +A Y
Sbjct: 406 EPVYSMEA-ADYREASSQQGLAYATEAVYESAEAPGHYPAEDSTYDEYENDLGITAVALY 464
Query: 1009 PYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
Y ++ ++ F+ + I + D WW G R G+FP+NYV
Sbjct: 465 DYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYV 509
Score = 36.3 bits (80), Expect = 0.72
Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 5/57 (8%)
Query: 1164 ALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
AL Y A +++S ++ + D GWW G KGR G FPA+YV++ Q
Sbjct: 462 ALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRG--VCKGR---YGLFPANYVELRQ 513
>BC007459-1|AAH07459.1| 217|Homo sapiens OSTF1 protein protein.
Length = 217
Score = 57.2 bits (132), Expect = 4e-07
Identities = 26/51 (50%), Positives = 33/51 (64%), Gaps = 1/51 (1%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
ALY + + DEL FE+ DII +TD S D WW+G +G GL PSNYV +
Sbjct: 22 ALYTFEPRTPDELYFEEGDIIYITDMS-DTNWWKGTSKGRTGLIPSNYVAE 71
Score = 48.4 bits (110), Expect = 2e-04
Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 3/67 (4%)
Query: 993 EPVSVEDDGEFYI--ASYPYSSSEPGDLVFEAGERIEVV-RRDGDWWTGRIGARTGIFPS 1049
+PV + G+ + A Y + P +L FE G+ I + D +WW G RTG+ PS
Sbjct: 7 KPVKPGEGGQVKVFRALYTFEPRTPDELYFEEGDIIYITDMSDTNWWKGTSKGRTGLIPS 66
Query: 1050 NYVSREA 1056
NYV+ +A
Sbjct: 67 NYVAEQA 73
Score = 37.1 bits (82), Expect = 0.41
Identities = 16/57 (28%), Positives = 34/57 (59%), Gaps = 5/57 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
++ +AL ++ +P++L +G ++ + +D+ WW+G +KGR G P++YV
Sbjct: 18 KVFRALYTFEPRTPDELYFEEGDIIYITDMSDTNWWKG--TSKGR---TGLIPSNYV 69
Score = 33.1 bits (72), Expect = 6.7
Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 3/63 (4%)
Query: 879 GEGPQPPRWRCVYPFVGRSADELSVQPGDLIVXXXXXXXXXXXXXXXXXRGQSGWFPESY 938
GEG Q +R +Y F R+ DEL + GD+I +G++G P +Y
Sbjct: 12 GEGGQVKVFRALYTFEPRTPDELYFEEGDII---YITDMSDTNWWKGTSKGRTGLIPSNY 68
Query: 939 VED 941
V +
Sbjct: 69 VAE 71
>AL683813-1|CAI39443.1| 776|Homo sapiens Rac/Cdc42 guanine nucleotide
exchange factor (GEF) 6 protein.
Length = 776
Score = 57.2 bits (132), Expect = 4e-07
Identities = 27/73 (36%), Positives = 46/73 (63%), Gaps = 6/73 (8%)
Query: 1153 VTGRRKHE-IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWF 1211
+T H+ IV+A ++ T+ ++LS+ KG ++ V + + GWWEG L N + GWF
Sbjct: 155 MTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTL-----NGRTGWF 209
Query: 1212 PASYVKVLQSSGR 1224
P++YV+ ++SS R
Sbjct: 210 PSNYVREIKSSER 222
Score = 52.8 bits (121), Expect = 8e-06
Identities = 26/54 (48%), Positives = 33/54 (61%), Gaps = 1/54 (1%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
V A + + N DELS K DII VT R ++ WW+G L G G FPSNYV ++
Sbjct: 165 VKARFNFKQTNEDELSVCKGDIIYVT-RVEEGGWWEGTLNGRTGWFPSNYVREI 217
Score = 44.4 bits (100), Expect = 0.003
Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 4/78 (5%)
Query: 979 GALPAVVDPGRTVSEPVSVEDDGEFYI---ASYPYSSSEPGDLVFEAGERIEVVR-RDGD 1034
GA+ + V + S+ V + ++G + A + + + +L G+ I V R +G
Sbjct: 137 GAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGG 196
Query: 1035 WWTGRIGARTGIFPSNYV 1052
WW G + RTG FPSNYV
Sbjct: 197 WWEGTLNGRTGWFPSNYV 214
>AL135783-5|CAI42903.1| 622|Homo sapiens Rac/Cdc42 guanine nucleotide
exchange factor (GEF) 6 protein.
Length = 622
Score = 57.2 bits (132), Expect = 4e-07
Identities = 27/73 (36%), Positives = 46/73 (63%), Gaps = 6/73 (8%)
Query: 1153 VTGRRKHE-IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWF 1211
+T H+ IV+A ++ T+ ++LS+ KG ++ V + + GWWEG L N + GWF
Sbjct: 1 MTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTL-----NGRTGWF 55
Query: 1212 PASYVKVLQSSGR 1224
P++YV+ ++SS R
Sbjct: 56 PSNYVREIKSSER 68
Score = 52.8 bits (121), Expect = 8e-06
Identities = 26/54 (48%), Positives = 33/54 (61%), Gaps = 1/54 (1%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
V A + + N DELS K DII VT R ++ WW+G L G G FPSNYV ++
Sbjct: 11 VKARFNFKQTNEDELSVCKGDIIYVT-RVEEGGWWEGTLNGRTGWFPSNYVREI 63
Score = 40.7 bits (91), Expect = 0.034
Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYV 1052
A + + + +L G+ I V R +G WW G + RTG FPSNYV
Sbjct: 13 ARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYV 60
>AL135783-1|CAI42899.1| 776|Homo sapiens Rac/Cdc42 guanine nucleotide
exchange factor (GEF) 6 protein.
Length = 776
Score = 57.2 bits (132), Expect = 4e-07
Identities = 27/73 (36%), Positives = 46/73 (63%), Gaps = 6/73 (8%)
Query: 1153 VTGRRKHE-IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWF 1211
+T H+ IV+A ++ T+ ++LS+ KG ++ V + + GWWEG L N + GWF
Sbjct: 155 MTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTL-----NGRTGWF 209
Query: 1212 PASYVKVLQSSGR 1224
P++YV+ ++SS R
Sbjct: 210 PSNYVREIKSSER 222
Score = 52.8 bits (121), Expect = 8e-06
Identities = 26/54 (48%), Positives = 33/54 (61%), Gaps = 1/54 (1%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
V A + + N DELS K DII VT R ++ WW+G L G G FPSNYV ++
Sbjct: 165 VKARFNFKQTNEDELSVCKGDIIYVT-RVEEGGWWEGTLNGRTGWFPSNYVREI 217
Score = 44.4 bits (100), Expect = 0.003
Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 4/78 (5%)
Query: 979 GALPAVVDPGRTVSEPVSVEDDGEFYI---ASYPYSSSEPGDLVFEAGERIEVVR-RDGD 1034
GA+ + V + S+ V + ++G + A + + + +L G+ I V R +G
Sbjct: 137 GAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGG 196
Query: 1035 WWTGRIGARTGIFPSNYV 1052
WW G + RTG FPSNYV
Sbjct: 197 WWEGTLNGRTGWFPSNYV 214
>AL133548-4|CAH71573.1| 214|Homo sapiens osteoclast stimulating
factor 1 protein.
Length = 214
Score = 57.2 bits (132), Expect = 4e-07
Identities = 26/51 (50%), Positives = 33/51 (64%), Gaps = 1/51 (1%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
ALY + + DEL FE+ DII +TD S D WW+G +G GL PSNYV +
Sbjct: 19 ALYTFEPRTPDELYFEEGDIIYITDMS-DTNWWKGTSKGRTGLIPSNYVAE 68
Score = 46.8 bits (106), Expect = 5e-04
Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVV-RRDGDWWTGRIGARTGIFPSNYVSREA 1056
A Y + P +L FE G+ I + D +WW G RTG+ PSNYV+ +A
Sbjct: 19 ALYTFEPRTPDELYFEEGDIIYITDMSDTNWWKGTSKGRTGLIPSNYVAEQA 70
Score = 37.1 bits (82), Expect = 0.41
Identities = 16/57 (28%), Positives = 34/57 (59%), Gaps = 5/57 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
++ +AL ++ +P++L +G ++ + +D+ WW+G +KGR G P++YV
Sbjct: 15 KVFRALYTFEPRTPDELYFEEGDIIYITDMSDTNWWKG--TSKGR---TGLIPSNYV 66
>AK222613-1|BAD96333.1| 550|Homo sapiens cortactin isoform a variant
protein.
Length = 550
Score = 57.2 bits (132), Expect = 4e-07
Identities = 26/50 (52%), Positives = 32/50 (64%), Gaps = 1/50 (2%)
Query: 1250 VALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
VALY Y A DE+SF+ DDII + D WW+G +G GLFP+NYV
Sbjct: 498 VALYDYQAAGDDEISFDPDDIITNIEMIDD-GWWRGVCKGRYGLFPANYV 546
Score = 37.9 bits (84), Expect = 0.24
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 10/105 (9%)
Query: 957 EPKTQLEGIAEVPEQEATSDLGGALPAVVD----PGRTVSEPVSVE----DDGEFYIASY 1008
EP +E A+ E + L A AV + PG +E + + D G +A Y
Sbjct: 443 EPVYSMEA-ADYREASSQQGLAYATEAVYESAEAPGHYPAEDSTYDEYENDLGITAVALY 501
Query: 1009 PYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
Y ++ ++ F+ + I + D WW G R G+FP+NYV
Sbjct: 502 DYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYV 546
Score = 36.3 bits (80), Expect = 0.72
Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 5/57 (8%)
Query: 1164 ALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
AL Y A +++S ++ + D GWW G KGR G FPA+YV++ Q
Sbjct: 499 ALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRG--VCKGR---YGLFPANYVELRQ 550
>AK222596-1|BAD96316.1| 214|Homo sapiens osteoclast stimulating
factor 1 variant protein.
Length = 214
Score = 57.2 bits (132), Expect = 4e-07
Identities = 26/51 (50%), Positives = 33/51 (64%), Gaps = 1/51 (1%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
ALY + + DEL FE+ DII +TD S D WW+G +G GL PSNYV +
Sbjct: 19 ALYTFEPRTPDELYFEEGDIIYITDMS-DTNWWKGTSKGRTGLIPSNYVAE 68
Score = 46.8 bits (106), Expect = 5e-04
Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVV-RRDGDWWTGRIGARTGIFPSNYVSREA 1056
A Y + P +L FE G+ I + D +WW G RTG+ PSNYV+ +A
Sbjct: 19 ALYTFEPRTPDELYFEEGDIIYITDMSDTNWWKGTSKGRTGLIPSNYVAEQA 70
Score = 37.1 bits (82), Expect = 0.41
Identities = 16/57 (28%), Positives = 34/57 (59%), Gaps = 5/57 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
++ +AL ++ +P++L +G ++ + +D+ WW+G +KGR G P++YV
Sbjct: 15 KVFRALYTFEPRTPDELYFEEGDIIYITDMSDTNWWKG--TSKGR---TGLIPSNYV 66
>D63476-1|BAA09763.2| 802|Homo sapiens KIAA0142 protein.
Length = 802
Score = 56.4 bits (130), Expect = 6e-07
Identities = 36/97 (37%), Positives = 55/97 (56%), Gaps = 7/97 (7%)
Query: 1212 PASY-VKVLQSSGRTS--GRTTPVLSSKMDALP-TETVIDKVV--ALYPYTAQNADELSF 1265
P+S+ +K S G S RT+ + + +L T+ +++V A + + N DELSF
Sbjct: 124 PSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSF 183
Query: 1266 EKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
K D+I VT R ++ WW+G L G G FPSNYV ++
Sbjct: 184 SKGDVIHVT-RVEEGGWWEGTLNGRTGWFPSNYVREV 219
Score = 54.8 bits (126), Expect = 2e-06
Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
+V+A ++ T+ ++LS KG ++ V + + GWWEG L N + GWFP++YV+ ++
Sbjct: 166 VVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTL-----NGRTGWFPSNYVREVK 220
Query: 1221 SSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+S + + L S T T I+K + Y QN E E
Sbjct: 221 ASEKPVSPKSGTLKSPPKGFDT-TAINK--SYYNVVLQNILETENE 263
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYV 1052
A + + + +L F G+ I V R +G WW G + RTG FPSNYV
Sbjct: 169 AKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV 216
>BC060776-1|AAH60776.1| 803|Homo sapiens ARHGEF7 protein protein.
Length = 803
Score = 56.4 bits (130), Expect = 6e-07
Identities = 36/97 (37%), Positives = 55/97 (56%), Gaps = 7/97 (7%)
Query: 1212 PASY-VKVLQSSGRTS--GRTTPVLSSKMDALP-TETVIDKVV--ALYPYTAQNADELSF 1265
P+S+ +K S G S RT+ + + +L T+ +++V A + + N DELSF
Sbjct: 146 PSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSF 205
Query: 1266 EKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
K D+I VT R ++ WW+G L G G FPSNYV ++
Sbjct: 206 SKGDVIHVT-RVEEGGWWEGTLNGRTGWFPSNYVREV 241
Score = 54.8 bits (126), Expect = 2e-06
Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
+V+A ++ T+ ++LS KG ++ V + + GWWEG L N + GWFP++YV+ ++
Sbjct: 188 VVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTL-----NGRTGWFPSNYVREVK 242
Query: 1221 SSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+S + + L S T T I+K + Y QN E E
Sbjct: 243 ASEKPVSPKSGTLKSPPKGFDT-TAINK--SYYNVVLQNILETENE 285
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYV 1052
A + + + +L F G+ I V R +G WW G + RTG FPSNYV
Sbjct: 191 AKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV 238
>BC050521-1|AAH50521.1| 764|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 764
Score = 56.4 bits (130), Expect = 6e-07
Identities = 36/97 (37%), Positives = 55/97 (56%), Gaps = 7/97 (7%)
Query: 1212 PASY-VKVLQSSGRTS--GRTTPVLSSKMDALP-TETVIDKVV--ALYPYTAQNADELSF 1265
P+S+ +K S G S RT+ + + +L T+ +++V A + + N DELSF
Sbjct: 86 PSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSF 145
Query: 1266 EKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
K D+I VT R ++ WW+G L G G FPSNYV ++
Sbjct: 146 SKGDVIHVT-RVEEGGWWEGTLNGRTGWFPSNYVREV 181
Score = 54.8 bits (126), Expect = 2e-06
Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
+V+A ++ T+ ++LS KG ++ V + + GWWEG L N + GWFP++YV+ ++
Sbjct: 128 VVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTL-----NGRTGWFPSNYVREVK 182
Query: 1221 SSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+S + + L S T T I+K + Y QN E E
Sbjct: 183 ASEKPVSPKSGTLKSPPKGFDT-TAINK--SYYNVVLQNILETENE 225
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYV 1052
A + + + +L F G+ I V R +G WW G + RTG FPSNYV
Sbjct: 131 AKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV 178
>BC033905-1|AAH33905.1| 753|Homo sapiens ARHGEF7 protein protein.
Length = 753
Score = 56.4 bits (130), Expect = 6e-07
Identities = 36/97 (37%), Positives = 55/97 (56%), Gaps = 7/97 (7%)
Query: 1212 PASY-VKVLQSSGRTS--GRTTPVLSSKMDALP-TETVIDKVV--ALYPYTAQNADELSF 1265
P+S+ +K S G S RT+ + + +L T+ +++V A + + N DELSF
Sbjct: 96 PSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSF 155
Query: 1266 EKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
K D+I VT R ++ WW+G L G G FPSNYV ++
Sbjct: 156 SKGDVIHVT-RVEEGGWWEGTLNGRTGWFPSNYVREV 191
Score = 54.8 bits (126), Expect = 2e-06
Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
+V+A ++ T+ ++LS KG ++ V + + GWWEG L N + GWFP++YV+ ++
Sbjct: 138 VVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTL-----NGRTGWFPSNYVREVK 192
Query: 1221 SSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+S + + L S T T I+K + Y QN E E
Sbjct: 193 ASEKPVSPKSGTLKSPPKGFDT-TAINK--SYYNVVLQNILETENE 235
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYV 1052
A + + + +L F G+ I V R +G WW G + RTG FPSNYV
Sbjct: 141 AKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV 188
>AL834228-1|CAD38906.1| 812|Homo sapiens hypothetical protein
protein.
Length = 812
Score = 56.4 bits (130), Expect = 6e-07
Identities = 36/97 (37%), Positives = 55/97 (56%), Gaps = 7/97 (7%)
Query: 1212 PASY-VKVLQSSGRTS--GRTTPVLSSKMDALP-TETVIDKVV--ALYPYTAQNADELSF 1265
P+S+ +K S G S RT+ + + +L T+ +++V A + + N DELSF
Sbjct: 155 PSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSF 214
Query: 1266 EKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
K D+I VT R ++ WW+G L G G FPSNYV ++
Sbjct: 215 SKGDVIHVT-RVEEGGWWEGTLNGRTGWFPSNYVREV 250
Score = 54.8 bits (126), Expect = 2e-06
Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
+V+A ++ T+ ++LS KG ++ V + + GWWEG L N + GWFP++YV+ ++
Sbjct: 197 VVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTL-----NGRTGWFPSNYVREVK 251
Query: 1221 SSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+S + + L S T T I+K + Y QN E E
Sbjct: 252 ASEKPVSPKSGTLKSPPKGFDT-TAINK--SYYNVVLQNILETENE 294
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYV 1052
A + + + +L F G+ I V R +G WW G + RTG FPSNYV
Sbjct: 200 AKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV 247
>AF329268-1|AAO13348.1| 404|Homo sapiens SH3-domain kinase binding
protein 1 protein.
Length = 404
Score = 56.4 bits (130), Expect = 6e-07
Identities = 24/57 (42%), Positives = 36/57 (63%), Gaps = 1/57 (1%)
Query: 1247 DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ-DPAWWQGELRGMVGLFPSNYVTKL 1302
D ++PY AQN DEL+ ++ DI+ + ++ D WW+GEL G G+FP N+V L
Sbjct: 9 DYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLL 65
Score = 40.3 bits (90), Expect = 0.044
Identities = 14/48 (29%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query: 1008 YPYSSSEPGDLVFEAGERIEVVRRDG---DWWTGRIGARTGIFPSNYV 1052
+PY + +L + G+ + ++ +D WW G + R G+FP N+V
Sbjct: 15 FPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFV 62
Score = 38.7 bits (86), Expect = 0.14
Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 7/65 (10%)
Query: 1157 RKHEIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKGRNRQVGWFPAS 1214
+ + + + Y A + ++L++ +G ++ + K D GWWEGEL N + G FP +
Sbjct: 6 KSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL-----NGRRGVFPDN 60
Query: 1215 YVKVL 1219
+VK+L
Sbjct: 61 FVKLL 65
>AF329267-1|AAK95587.1| 404|Homo sapiens SH3-domain kinase binding
protein 1 protein.
Length = 404
Score = 56.4 bits (130), Expect = 6e-07
Identities = 24/57 (42%), Positives = 36/57 (63%), Gaps = 1/57 (1%)
Query: 1247 DKVVALYPYTAQNADELSFEKDDIIAVTDRSQ-DPAWWQGELRGMVGLFPSNYVTKL 1302
D ++PY AQN DEL+ ++ DI+ + ++ D WW+GEL G G+FP N+V L
Sbjct: 9 DYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLL 65
Score = 40.3 bits (90), Expect = 0.044
Identities = 14/48 (29%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query: 1008 YPYSSSEPGDLVFEAGERIEVVRRDG---DWWTGRIGARTGIFPSNYV 1052
+PY + +L + G+ + ++ +D WW G + R G+FP N+V
Sbjct: 15 FPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFV 62
Score = 38.7 bits (86), Expect = 0.14
Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 7/65 (10%)
Query: 1157 RKHEIVQALASYTATSPEQLSLMKGQLLVVRKK--ADSGWWEGELQAKGRNRQVGWFPAS 1214
+ + + + Y A + ++L++ +G ++ + K D GWWEGEL N + G FP +
Sbjct: 6 KSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGEL-----NGRRGVFPDN 60
Query: 1215 YVKVL 1219
+VK+L
Sbjct: 61 FVKLL 65
>AB177848-1|BAD66826.1| 691|Homo sapiens KIAA0142 splice variant 1
protein.
Length = 691
Score = 56.4 bits (130), Expect = 6e-07
Identities = 36/97 (37%), Positives = 55/97 (56%), Gaps = 7/97 (7%)
Query: 1212 PASY-VKVLQSSGRTS--GRTTPVLSSKMDALP-TETVIDKVV--ALYPYTAQNADELSF 1265
P+S+ +K S G S RT+ + + +L T+ +++V A + + N DELSF
Sbjct: 124 PSSHRIKSFDSLGSQSLHTRTSKLFQGQYRSLDMTDNSNNQLVVRAKFNFQQTNEDELSF 183
Query: 1266 EKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
K D+I VT R ++ WW+G L G G FPSNYV ++
Sbjct: 184 SKGDVIHVT-RVEEGGWWEGTLNGRTGWFPSNYVREV 219
Score = 54.8 bits (126), Expect = 2e-06
Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
+V+A ++ T+ ++LS KG ++ V + + GWWEG L N + GWFP++YV+ ++
Sbjct: 166 VVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTL-----NGRTGWFPSNYVREVK 220
Query: 1221 SSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+S + + L S T T I+K + Y QN E E
Sbjct: 221 ASEKPVSPKSGTLKSPPKGFDT-TAINK--SYYNVVLQNILETENE 263
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYV 1052
A + + + +L F G+ I V R +G WW G + RTG FPSNYV
Sbjct: 169 AKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV 216
>BC053671-1|AAH53671.1| 1056|Homo sapiens SH3RF1 protein protein.
Length = 1056
Score = 56.0 bits (129), Expect = 8e-07
Identities = 40/137 (29%), Positives = 65/137 (47%), Gaps = 22/137 (16%)
Query: 1163 QALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSS 1222
+AL +Y P L KG ++++R++ D W+ GE+ N G+FP ++V+++
Sbjct: 140 KALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEV-----NGIHGFFPTNFVQII--- 191
Query: 1223 GRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAW 1282
+ P + AL V DK + D L F KDD++ V R D W
Sbjct: 192 -----KPLPQPPPQCKALYDFEVKDK--------EADKDCLPFAKDDVLTVI-RRVDENW 237
Query: 1283 WQGELRGMVGLFPSNYV 1299
+G L +G+FP +YV
Sbjct: 238 AEGMLADKIGIFPISYV 254
Score = 56.0 bits (129), Expect = 8e-07
Identities = 40/137 (29%), Positives = 65/137 (47%), Gaps = 22/137 (16%)
Query: 1163 QALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSS 1222
+AL +Y P L KG ++++R++ D W+ GE+ N G+FP ++V+++
Sbjct: 308 KALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEV-----NGIHGFFPTNFVQII--- 359
Query: 1223 GRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAW 1282
+ P + AL V DK + D L F KDD++ V R D W
Sbjct: 360 -----KPLPQPPPQCKALYDFEVKDK--------EADKDCLPFAKDDVLTVI-RRVDENW 405
Query: 1283 WQGELRGMVGLFPSNYV 1299
+G L +G+FP +YV
Sbjct: 406 AEGMLADKIGIFPISYV 422
Score = 47.2 bits (107), Expect = 4e-04
Identities = 41/144 (28%), Positives = 61/144 (42%), Gaps = 26/144 (18%)
Query: 1176 LSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSS------------G 1223
L K +L V ++ D W EG L K +G FP SYV+ ++ G
Sbjct: 219 LPFAKDDVLTVIRRVDENWAEGMLADK-----IGIFPISYVEFNSAAKQLIEWDKPPVPG 273
Query: 1224 RTSGRTTPVLSSKMDAL------PTETV--IDKVVALYPYTAQNADELSFEKDDIIAVTD 1275
+G + + A P + + ALY Y + +L F K DII +
Sbjct: 274 VDAGECSSAAAQSSTAPKHSWSPPVRGIPQLPCAKALYNYEGKEPGDLKFSKGDII-ILR 332
Query: 1276 RSQDPAWWQGELRGMVGLFPSNYV 1299
R D W+ GE+ G+ G FP+N+V
Sbjct: 333 RQVDENWYHGEVNGIHGFFPTNFV 356
Score = 46.4 bits (105), Expect = 7e-04
Identities = 22/52 (42%), Positives = 31/52 (59%), Gaps = 3/52 (5%)
Query: 1250 VALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGEL--RGMVGLFPSNYV 1299
VA+YPYT + DEL K ++ V +R QD W++G +G+FP NYV
Sbjct: 619 VAIYPYTPRKEDELELRKGEMFLVFERCQD-GWFKGTSMHTSKIGVFPGNYV 669
Score = 46.0 bits (104), Expect = 9e-04
Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 959 KTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDL 1018
++Q +A ++ S GG P V ++ S PV A Y Y EPGDL
Sbjct: 98 RSQSSTVANCSSKDLQSSQGGQQPRV----QSWSPPVRGIPQLPCAKALYNYEGKEPGDL 153
Query: 1019 VFEAGERIEVVRR--DGDWWTGRIGARTGIFPSNYV 1052
F G+ I ++RR D +W+ G + G FP+N+V
Sbjct: 154 KFSKGD-IIILRRQVDENWYHGEVNGIHGFFPTNFV 188
Score = 45.2 bits (102), Expect = 0.002
Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 3/55 (5%)
Query: 1163 QALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
+ + SY S +L L +G ++ V KK + GW++G LQ RN + G FP S+V+
Sbjct: 1003 RVVVSYPPQSEAELELKEGDIVFVHKKREDGWFKGTLQ---RNGKTGLFPGSFVE 1054
Score = 44.8 bits (101), Expect = 0.002
Identities = 40/123 (32%), Positives = 55/123 (44%), Gaps = 15/123 (12%)
Query: 932 GWFPESYVEDLNAPTAFVTEVIETLEPKTQLEGIAEVPEQEATSDLGGALPAVVDPGRTV 991
G FP SYVE +A ++IE +P VP +A A + P +
Sbjct: 247 GIFPISYVEFNSA----AKQLIEWDKPP--------VPGVDAGECSSAAAQSSTAPKHSW 294
Query: 992 SEPVSVEDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRR--DGDWWTGRIGARTGIFPS 1049
S PV A Y Y EPGDL F G+ I ++RR D +W+ G + G FP+
Sbjct: 295 SPPVRGIPQLPCAKALYNYEGKEPGDLKFSKGD-IIILRRQVDENWYHGEVNGIHGFFPT 353
Query: 1050 NYV 1052
N+V
Sbjct: 354 NFV 356
Score = 38.3 bits (85), Expect = 0.18
Identities = 19/53 (35%), Positives = 27/53 (50%), Gaps = 3/53 (5%)
Query: 1004 YIASYPYSSSEPGDLVFEAGERIEVVRRDGDWW---TGRIGARTGIFPSNYVS 1053
Y+A YPY+ + +L GE V R D W T ++ G+FP NYV+
Sbjct: 618 YVAIYPYTPRKEDELELRKGEMFLVFERCQDGWFKGTSMHTSKIGVFPGNYVA 670
Score = 36.7 bits (81), Expect = 0.55
Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Query: 1164 ALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
A+ YT ++L L KG++ +V ++ GW++G ++G FP +YV
Sbjct: 620 AIYPYTPRKEDELELRKGEMFLVFERCQDGWFKG---TSMHTSKIGVFPGNYV 669
>BC041023-1|AAH41023.1| 302|Homo sapiens SH3RF1 protein protein.
Length = 302
Score = 56.0 bits (129), Expect = 8e-07
Identities = 40/137 (29%), Positives = 65/137 (47%), Gaps = 22/137 (16%)
Query: 1163 QALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSS 1222
+AL +Y P L KG ++++R++ D W+ GE+ N G+FP ++V+++
Sbjct: 1 KALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEV-----NGIHGFFPTNFVQII--- 52
Query: 1223 GRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAW 1282
+ P + AL V DK + D L F KDD++ V R D W
Sbjct: 53 -----KPLPQPPPQCKALYDFEVKDK--------EADKDCLPFAKDDVLTVI-RRVDENW 98
Query: 1283 WQGELRGMVGLFPSNYV 1299
+G L +G+FP +YV
Sbjct: 99 AEGMLADKIGIFPISYV 115
Score = 43.2 bits (97), Expect = 0.006
Identities = 21/49 (42%), Positives = 29/49 (59%), Gaps = 3/49 (6%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVRR--DGDWWTGRIGARTGIFPSNYV 1052
A Y Y EPGDL F G+ I ++RR D +W+ G + G FP+N+V
Sbjct: 2 ALYNYEGKEPGDLKFSKGD-IIILRRQVDENWYHGEVNGIHGFFPTNFV 49
>AL390754-5|CAM13628.1| 646|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 646
Score = 56.0 bits (129), Expect = 8e-07
Identities = 26/54 (48%), Positives = 34/54 (62%), Gaps = 1/54 (1%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
V A + + N DELSF K D+I VT R ++ WW+G L G G FPSNYV ++
Sbjct: 11 VRAKFNFQQTNEDELSFSKGDVIHVT-RVEEGGWWEGTLNGRTGWFPSNYVREV 63
Score = 54.8 bits (126), Expect = 2e-06
Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
+V+A ++ T+ ++LS KG ++ V + + GWWEG L N + GWFP++YV+ ++
Sbjct: 10 VVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTL-----NGRTGWFPSNYVREVK 64
Query: 1221 SSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+S + + L S T T I+K + Y QN E E
Sbjct: 65 ASEKPVSPKSGTLKSPPKGFDT-TAINK--SYYNVVLQNILETENE 107
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYV 1052
A + + + +L F G+ I V R +G WW G + RTG FPSNYV
Sbjct: 13 AKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV 60
>AL390754-4|CAI12463.1| 705|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 705
Score = 56.0 bits (129), Expect = 8e-07
Identities = 26/54 (48%), Positives = 34/54 (62%), Gaps = 1/54 (1%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
V A + + N DELSF K D+I VT R ++ WW+G L G G FPSNYV ++
Sbjct: 11 VRAKFNFQQTNEDELSFSKGDVIHVT-RVEEGGWWEGTLNGRTGWFPSNYVREV 63
Score = 54.8 bits (126), Expect = 2e-06
Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
+V+A ++ T+ ++LS KG ++ V + + GWWEG L N + GWFP++YV+ ++
Sbjct: 10 VVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTL-----NGRTGWFPSNYVREVK 64
Query: 1221 SSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+S + + L S T T I+K + Y QN E E
Sbjct: 65 ASEKPVSPKSGTLKSPPKGFDT-TAINK--SYYNVVLQNILETENE 107
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYV 1052
A + + + +L F G+ I V R +G WW G + RTG FPSNYV
Sbjct: 13 AKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV 60
>AL390754-3|CAI12462.1| 66|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 66
Score = 56.0 bits (129), Expect = 8e-07
Identities = 26/54 (48%), Positives = 34/54 (62%), Gaps = 1/54 (1%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
V A + + N DELSF K D+I VT R ++ WW+G L G G FPSNYV ++
Sbjct: 11 VRAKFNFQQTNEDELSFSKGDVIHVT-RVEEGGWWEGTLNGRTGWFPSNYVREV 63
Score = 52.0 bits (119), Expect = 1e-05
Identities = 22/62 (35%), Positives = 40/62 (64%), Gaps = 5/62 (8%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
+V+A ++ T+ ++LS KG ++ V + + GWWEG L N + GWFP++YV+ ++
Sbjct: 10 VVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTL-----NGRTGWFPSNYVREVK 64
Query: 1221 SS 1222
+S
Sbjct: 65 AS 66
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYV 1052
A + + + +L F G+ I V R +G WW G + RTG FPSNYV
Sbjct: 13 AKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV 60
>AL390754-2|CAI12461.1| 625|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 625
Score = 56.0 bits (129), Expect = 8e-07
Identities = 26/54 (48%), Positives = 34/54 (62%), Gaps = 1/54 (1%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
V A + + N DELSF K D+I VT R ++ WW+G L G G FPSNYV ++
Sbjct: 11 VRAKFNFQQTNEDELSFSKGDVIHVT-RVEEGGWWEGTLNGRTGWFPSNYVREV 63
Score = 54.8 bits (126), Expect = 2e-06
Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
+V+A ++ T+ ++LS KG ++ V + + GWWEG L N + GWFP++YV+ ++
Sbjct: 10 VVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTL-----NGRTGWFPSNYVREVK 64
Query: 1221 SSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+S + + L S T T I+K + Y QN E E
Sbjct: 65 ASEKPVSPKSGTLKSPPKGFDT-TAINK--SYYNVVLQNILETENE 107
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYV 1052
A + + + +L F G+ I V R +G WW G + RTG FPSNYV
Sbjct: 13 AKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV 60
>AL390754-1|CAI12460.1| 123|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 123
Score = 56.0 bits (129), Expect = 8e-07
Identities = 26/54 (48%), Positives = 34/54 (62%), Gaps = 1/54 (1%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
V A + + N DELSF K D+I VT R ++ WW+G L G G FPSNYV ++
Sbjct: 11 VRAKFNFQQTNEDELSFSKGDVIHVT-RVEEGGWWEGTLNGRTGWFPSNYVREV 63
Score = 54.8 bits (126), Expect = 2e-06
Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
+V+A ++ T+ ++LS KG ++ V + + GWWEG L N + GWFP++YV+ ++
Sbjct: 10 VVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTL-----NGRTGWFPSNYVREVK 64
Query: 1221 SSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+S + + L S T T I+K + Y QN E E
Sbjct: 65 ASEKPVSPKSGTLKSPPKGFDT-TAINK--SYYNVVLQNILETENE 107
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYV 1052
A + + + +L F G+ I V R +G WW G + RTG FPSNYV
Sbjct: 13 AKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV 60
>AL139086-4|CAM20788.1| 646|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 646
Score = 56.0 bits (129), Expect = 8e-07
Identities = 26/54 (48%), Positives = 34/54 (62%), Gaps = 1/54 (1%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
V A + + N DELSF K D+I VT R ++ WW+G L G G FPSNYV ++
Sbjct: 11 VRAKFNFQQTNEDELSFSKGDVIHVT-RVEEGGWWEGTLNGRTGWFPSNYVREV 63
Score = 54.8 bits (126), Expect = 2e-06
Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
+V+A ++ T+ ++LS KG ++ V + + GWWEG L N + GWFP++YV+ ++
Sbjct: 10 VVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTL-----NGRTGWFPSNYVREVK 64
Query: 1221 SSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+S + + L S T T I+K + Y QN E E
Sbjct: 65 ASEKPVSPKSGTLKSPPKGFDT-TAINK--SYYNVVLQNILETENE 107
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYV 1052
A + + + +L F G+ I V R +G WW G + RTG FPSNYV
Sbjct: 13 AKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV 60
>AL139086-3|CAI14672.1| 705|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 705
Score = 56.0 bits (129), Expect = 8e-07
Identities = 26/54 (48%), Positives = 34/54 (62%), Gaps = 1/54 (1%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
V A + + N DELSF K D+I VT R ++ WW+G L G G FPSNYV ++
Sbjct: 11 VRAKFNFQQTNEDELSFSKGDVIHVT-RVEEGGWWEGTLNGRTGWFPSNYVREV 63
Score = 54.8 bits (126), Expect = 2e-06
Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
+V+A ++ T+ ++LS KG ++ V + + GWWEG L N + GWFP++YV+ ++
Sbjct: 10 VVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTL-----NGRTGWFPSNYVREVK 64
Query: 1221 SSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+S + + L S T T I+K + Y QN E E
Sbjct: 65 ASEKPVSPKSGTLKSPPKGFDT-TAINK--SYYNVVLQNILETENE 107
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYV 1052
A + + + +L F G+ I V R +G WW G + RTG FPSNYV
Sbjct: 13 AKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV 60
>AL139086-2|CAI14671.1| 625|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 625
Score = 56.0 bits (129), Expect = 8e-07
Identities = 26/54 (48%), Positives = 34/54 (62%), Gaps = 1/54 (1%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
V A + + N DELSF K D+I VT R ++ WW+G L G G FPSNYV ++
Sbjct: 11 VRAKFNFQQTNEDELSFSKGDVIHVT-RVEEGGWWEGTLNGRTGWFPSNYVREV 63
Score = 54.8 bits (126), Expect = 2e-06
Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
+V+A ++ T+ ++LS KG ++ V + + GWWEG L N + GWFP++YV+ ++
Sbjct: 10 VVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTL-----NGRTGWFPSNYVREVK 64
Query: 1221 SSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+S + + L S T T I+K + Y QN E E
Sbjct: 65 ASEKPVSPKSGTLKSPPKGFDT-TAINK--SYYNVVLQNILETENE 107
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYV 1052
A + + + +L F G+ I V R +G WW G + RTG FPSNYV
Sbjct: 13 AKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV 60
>AL139086-1|CAI14670.1| 123|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 123
Score = 56.0 bits (129), Expect = 8e-07
Identities = 26/54 (48%), Positives = 34/54 (62%), Gaps = 1/54 (1%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
V A + + N DELSF K D+I VT R ++ WW+G L G G FPSNYV ++
Sbjct: 11 VRAKFNFQQTNEDELSFSKGDVIHVT-RVEEGGWWEGTLNGRTGWFPSNYVREV 63
Score = 54.8 bits (126), Expect = 2e-06
Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
+V+A ++ T+ ++LS KG ++ V + + GWWEG L N + GWFP++YV+ ++
Sbjct: 10 VVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTL-----NGRTGWFPSNYVREVK 64
Query: 1221 SSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+S + + L S T T I+K + Y QN E E
Sbjct: 65 ASEKPVSPKSGTLKSPPKGFDT-TAINK--SYYNVVLQNILETENE 107
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYV 1052
A + + + +L F G+ I V R +G WW G + RTG FPSNYV
Sbjct: 13 AKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV 60
>AK021429-1|BAB13822.1| 712|Homo sapiens protein ( Homo sapiens cDNA
FLJ11367 fis, clone HEMBA1000303, highly similar to Mus
musculus Plenty of SH3s (POSH) mRNA. ).
Length = 712
Score = 56.0 bits (129), Expect = 8e-07
Identities = 40/137 (29%), Positives = 65/137 (47%), Gaps = 22/137 (16%)
Query: 1163 QALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSS 1222
+AL +Y P L KG ++++R++ D W+ GE+ N G+FP ++V+++
Sbjct: 140 KALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEV-----NGIHGFFPTNFVQII--- 191
Query: 1223 GRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAW 1282
+ P + AL V DK + D L F KDD++ V R D W
Sbjct: 192 -----KPLPQPPPQCKALYDFEVKDK--------EADKDCLPFAKDDVLTVI-RRVDENW 237
Query: 1283 WQGELRGMVGLFPSNYV 1299
+G L +G+FP +YV
Sbjct: 238 AEGMLADKIGIFPISYV 254
Score = 46.4 bits (105), Expect = 7e-04
Identities = 22/52 (42%), Positives = 31/52 (59%), Gaps = 3/52 (5%)
Query: 1250 VALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGEL--RGMVGLFPSNYV 1299
VA+YPYT + DEL K ++ V +R QD W++G +G+FP NYV
Sbjct: 451 VAIYPYTPRKEDELELRKGEMFLVFERCQD-GWFKGTSMHTSKIGVFPGNYV 501
Score = 46.0 bits (104), Expect = 9e-04
Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 959 KTQLEGIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGEFYIASYPYSSSEPGDL 1018
++Q +A ++ S GG P V ++ S PV A Y Y EPGDL
Sbjct: 98 RSQSSTVANCSSKDLQSSQGGQQPRV----QSWSPPVRGIPQLPCAKALYNYEGKEPGDL 153
Query: 1019 VFEAGERIEVVRR--DGDWWTGRIGARTGIFPSNYV 1052
F G+ I ++RR D +W+ G + G FP+N+V
Sbjct: 154 KFSKGD-IIILRRQVDENWYHGEVNGIHGFFPTNFV 188
Score = 38.3 bits (85), Expect = 0.18
Identities = 19/53 (35%), Positives = 27/53 (50%), Gaps = 3/53 (5%)
Query: 1004 YIASYPYSSSEPGDLVFEAGERIEVVRRDGDWW---TGRIGARTGIFPSNYVS 1053
Y+A YPY+ + +L GE V R D W T ++ G+FP NYV+
Sbjct: 450 YVAIYPYTPRKEDELELRKGEMFLVFERCQDGWFKGTSMHTSKIGVFPGNYVA 502
Score = 36.7 bits (81), Expect = 0.55
Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 3/53 (5%)
Query: 1164 ALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
A+ YT ++L L KG++ +V ++ GW++G ++G FP +YV
Sbjct: 452 AIYPYTPRKEDELELRKGEMFLVFERCQDGWFKG---TSMHTSKIGVFPGNYV 501
>AB177849-1|BAD66827.1| 680|Homo sapiens KIAA0142 splice variant 2
protein.
Length = 680
Score = 56.0 bits (129), Expect = 8e-07
Identities = 26/54 (48%), Positives = 34/54 (62%), Gaps = 1/54 (1%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
V A + + N DELSF K D+I VT R ++ WW+G L G G FPSNYV ++
Sbjct: 45 VRAKFNFQQTNEDELSFSKGDVIHVT-RVEEGGWWEGTLNGRTGWFPSNYVREV 97
Score = 54.8 bits (126), Expect = 2e-06
Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 1161 IVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQ 1220
+V+A ++ T+ ++LS KG ++ V + + GWWEG L N + GWFP++YV+ ++
Sbjct: 44 VVRAKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTL-----NGRTGWFPSNYVREVK 98
Query: 1221 SSGRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFE 1266
+S + + L S T T I+K + Y QN E E
Sbjct: 99 ASEKPVSPKSGTLKSPPKGFDT-TAINK--SYYNVVLQNILETENE 141
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYV 1052
A + + + +L F G+ I V R +G WW G + RTG FPSNYV
Sbjct: 47 AKFNFQQTNEDELSFSKGDVIHVTRVEEGGWWEGTLNGRTGWFPSNYV 94
>Y10388-1|CAA71414.2| 759|Homo sapiens Graf protein protein.
Length = 759
Score = 55.6 bits (128), Expect = 1e-06
Identities = 27/69 (39%), Positives = 34/69 (49%)
Query: 1231 PVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGM 1290
P S+ D+ P T K ALY A++ ELSF + SQ+P W +G L G
Sbjct: 688 PTSSTSSDSSPVSTPFRKAKALYACKAEHDSELSFTAGTVFDNVHPSQEPGWLEGTLNGK 747
Query: 1291 VGLFPSNYV 1299
GL P NYV
Sbjct: 748 TGLIPENYV 756
>BC068555-1|AAH68555.1| 759|Homo sapiens ARHGAP26 protein protein.
Length = 759
Score = 55.6 bits (128), Expect = 1e-06
Identities = 27/69 (39%), Positives = 34/69 (49%)
Query: 1231 PVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGM 1290
P S+ D+ P T K ALY A++ ELSF + SQ+P W +G L G
Sbjct: 688 PTSSTSSDSSPVSTPFRKAKALYACKAEHDSELSFTAGTVFDNVHPSQEPGWLEGTLNGK 747
Query: 1291 VGLFPSNYV 1299
GL P NYV
Sbjct: 748 TGLIPENYV 756
>BC028740-1|AAH28740.1| 525|Homo sapiens signal transducing adaptor
molecule (SH3 domain and ITAM motif) 2 protein.
Length = 525
Score = 55.6 bits (128), Expect = 1e-06
Identities = 29/60 (48%), Positives = 38/60 (63%), Gaps = 1/60 (1%)
Query: 1245 VIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
V KV ALY + A +EL+F+ +II V D S D WW+GE +GLFPSN+VT +N
Sbjct: 203 VARKVRALYDFEAVEDNELTFKHGEIIIVLDDS-DANWWKGENHRGIGLFPSNFVTTNLN 261
Score = 41.1 bits (92), Expect = 0.025
Identities = 17/55 (30%), Positives = 33/55 (60%), Gaps = 5/55 (9%)
Query: 1162 VQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
V+AL + A +L+ G++++V +D+ WW+GE +R +G FP+++V
Sbjct: 207 VRALYDFEAVEDNELTFKHGEIIIVLDDSDANWWKGE-----NHRGIGLFPSNFV 256
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYVS 1053
A Y + + E +L F+ GE I V+ D +WW G G+FPSN+V+
Sbjct: 209 ALYDFEAVEDNELTFKHGEIIIVLDDSDANWWKGENHRGIGLFPSNFVT 257
>AF042274-1|AAC63964.1| 342|Homo sapiens signal transducing adaptor
molecule 2B protein.
Length = 342
Score = 55.6 bits (128), Expect = 1e-06
Identities = 29/60 (48%), Positives = 38/60 (63%), Gaps = 1/60 (1%)
Query: 1245 VIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
V KV ALY + A +EL+F+ +II V D S D WW+GE +GLFPSN+VT +N
Sbjct: 203 VARKVRALYDFEAVEDNELTFKHGEIIIVLDDS-DANWWKGENHRGIGLFPSNFVTTNLN 261
Score = 41.1 bits (92), Expect = 0.025
Identities = 17/55 (30%), Positives = 33/55 (60%), Gaps = 5/55 (9%)
Query: 1162 VQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
V+AL + A +L+ G++++V +D+ WW+GE +R +G FP+++V
Sbjct: 207 VRALYDFEAVEDNELTFKHGEIIIVLDDSDANWWKGE-----NHRGIGLFPSNFV 256
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYVS 1053
A Y + + E +L F+ GE I V+ D +WW G G+FPSN+V+
Sbjct: 209 ALYDFEAVEDNELTFKHGEIIIVLDDSDANWWKGENHRGIGLFPSNFVT 257
>AF042273-1|AAC63963.1| 525|Homo sapiens signal transducing adaptor
molecule 2A protein.
Length = 525
Score = 55.6 bits (128), Expect = 1e-06
Identities = 29/60 (48%), Positives = 38/60 (63%), Gaps = 1/60 (1%)
Query: 1245 VIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
V KV ALY + A +EL+F+ +II V D S D WW+GE +GLFPSN+VT +N
Sbjct: 203 VARKVRALYDFEAVEDNELTFKHGEIIIVLDDS-DANWWKGENHRGIGLFPSNFVTTNLN 261
Score = 41.1 bits (92), Expect = 0.025
Identities = 17/55 (30%), Positives = 33/55 (60%), Gaps = 5/55 (9%)
Query: 1162 VQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
V+AL + A +L+ G++++V +D+ WW+GE +R +G FP+++V
Sbjct: 207 VRALYDFEAVEDNELTFKHGEIIIVLDDSDANWWKGE-----NHRGIGLFPSNFV 256
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYVS 1053
A Y + + E +L F+ GE I V+ D +WW G G+FPSN+V+
Sbjct: 209 ALYDFEAVEDNELTFKHGEIIIVLDDSDANWWKGENHRGIGLFPSNFVT 257
>AC079790-2|AAY14712.1| 525|Homo sapiens unknown protein.
Length = 525
Score = 55.6 bits (128), Expect = 1e-06
Identities = 29/60 (48%), Positives = 38/60 (63%), Gaps = 1/60 (1%)
Query: 1245 VIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
V KV ALY + A +EL+F+ +II V D S D WW+GE +GLFPSN+VT +N
Sbjct: 203 VARKVRALYDFEAVEDNELTFKHGEIIIVLDDS-DANWWKGENHRGIGLFPSNFVTTNLN 261
Score = 41.1 bits (92), Expect = 0.025
Identities = 17/55 (30%), Positives = 33/55 (60%), Gaps = 5/55 (9%)
Query: 1162 VQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
V+AL + A +L+ G++++V +D+ WW+GE +R +G FP+++V
Sbjct: 207 VRALYDFEAVEDNELTFKHGEIIIVLDDSDANWWKGE-----NHRGIGLFPSNFV 256
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVVR-RDGDWWTGRIGARTGIFPSNYVS 1053
A Y + + E +L F+ GE I V+ D +WW G G+FPSN+V+
Sbjct: 209 ALYDFEAVEDNELTFKHGEIIIVLDDSDANWWKGENHRGIGLFPSNFVT 257
>Z82206-3|CAI42713.1| 330|Homo sapiens GRB2-related adaptor protein 2
protein.
Length = 330
Score = 55.2 bits (127), Expect = 1e-06
Identities = 23/52 (44%), Positives = 32/52 (61%), Gaps = 1/52 (1%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
ALY + A DEL F +++ V D S +P+WW G L +GLFP+NYV +
Sbjct: 278 ALYDFEALEDDELGFHSGEVVEVLD-SSNPSWWTGRLHNKLGLFPANYVAPM 328
Score = 49.6 bits (113), Expect = 7e-05
Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 4/93 (4%)
Query: 964 GIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGE--FYIASYPYSSSEPGDLVFE 1021
G ++ + + LG + A + R ++PV ++ G + A Y + + E +L F
Sbjct: 235 GSLDINDGHCGTGLGSEMNAAL-MHRRHTDPVQLQAAGRVRWARALYDFEALEDDELGFH 293
Query: 1022 AGERIEVVRRDG-DWWTGRIGARTGIFPSNYVS 1053
+GE +EV+ WWTGR+ + G+FP+NYV+
Sbjct: 294 SGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVA 326
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/52 (30%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+ VA + +TA DELSF D++ + ++ W++ EL G P N++
Sbjct: 2 EAVAKFDFTASGEDELSFHTGDVLKILSNQEE--WFKAELGSQEGYVPKNFI 51
Score = 35.5 bits (78), Expect = 1.3
Identities = 10/48 (20%), Positives = 28/48 (58%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIFPSNYV 1052
+A + +++S +L F G+ ++++ +W+ +G++ G P N++
Sbjct: 4 VAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFI 51
>Y18051-1|CAA77021.1| 330|Homo sapiens GADS protein protein.
Length = 330
Score = 55.2 bits (127), Expect = 1e-06
Identities = 23/52 (44%), Positives = 32/52 (61%), Gaps = 1/52 (1%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
ALY + A DEL F +++ V D S +P+WW G L +GLFP+NYV +
Sbjct: 278 ALYDFEALEDDELGFHSGEVVEVLD-SSNPSWWTGRLHNKLGLFPANYVAPM 328
Score = 49.6 bits (113), Expect = 7e-05
Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 4/93 (4%)
Query: 964 GIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGE--FYIASYPYSSSEPGDLVFE 1021
G ++ + + LG + A + R ++PV ++ G + A Y + + E +L F
Sbjct: 235 GSLDINDGHCGTGLGSEMNAAL-MHRRHTDPVQLQAAGRVRWARALYDFEALEDDELGFH 293
Query: 1022 AGERIEVVRRDG-DWWTGRIGARTGIFPSNYVS 1053
+GE +EV+ WWTGR+ + G+FP+NYV+
Sbjct: 294 SGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVA 326
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/52 (30%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+ VA + +TA DELSF D++ + ++ W++ EL G P N++
Sbjct: 2 EAVAKFDFTASGEDELSFHTGDVLKILSNQEE--WFKAELGSQEGYVPKNFI 51
Score = 35.5 bits (78), Expect = 1.3
Identities = 10/48 (20%), Positives = 28/48 (58%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIFPSNYV 1052
+A + +++S +L F G+ ++++ +W+ +G++ G P N++
Sbjct: 4 VAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFI 51
>X62852-1|CAA44664.1| 160|Homo sapiens ash protein protein.
Length = 160
Score = 55.2 bits (127), Expect = 1e-06
Identities = 25/52 (48%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVT 1300
V AL+ + Q EL F + D I V D S DP WW+G G G+FP NYVT
Sbjct: 104 VQALFDFDPQEDGELGFRRGDFIHVMDNS-DPNWWKGACHGQTGMFPRNYVT 154
Score = 43.2 bits (97), Expect = 0.006
Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVV-RRDGDWWTGRIGARTGIFPSNYVS 1053
A + + E G+L F G+ I V+ D +WW G +TG+FP NYV+
Sbjct: 106 ALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVT 154
Score = 33.9 bits (74), Expect = 3.8
Identities = 17/55 (30%), Positives = 24/55 (43%), Gaps = 5/55 (9%)
Query: 1162 VQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
VQAL + +L +G + V +D WW+G Q G FP +YV
Sbjct: 104 VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHG-----QTGMFPRNYV 153
>U87166-1|AAC39757.1| 508|Homo sapiens spectrin SH3 domain binding
protein 1 protein.
Length = 508
Score = 55.2 bits (127), Expect = 1e-06
Identities = 26/59 (44%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
I+KVVA+Y YT DELSF + II V ++ D W++G + GLFP NYV +++
Sbjct: 448 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD-GWYEGVCNRVTGLFPGNYVESIMH 505
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS M+G ++ V KK D GW+EG NR G FP +YV+
Sbjct: 449 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 501
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 1002 EFYIASYPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYV 1052
E +A Y Y+ + +L F G I V++++ D W+ G TG+FP NYV
Sbjct: 449 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYV 500
>M96995-1|AAA58448.1| 217|Homo sapiens epidermal growth factor
receptor-binding protein GRB2 protein.
Length = 217
Score = 55.2 bits (127), Expect = 1e-06
Identities = 25/52 (48%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVT 1300
V AL+ + Q EL F + D I V D S DP WW+G G G+FP NYVT
Sbjct: 161 VQALFDFDPQEDGELGFRRGDFIHVMDNS-DPNWWKGACHGQTGMFPRNYVT 211
Score = 48.0 bits (109), Expect = 2e-04
Identities = 20/52 (38%), Positives = 30/52 (57%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+ +A Y + A DELSF++ DI+ V + D W++ EL G G P NY+
Sbjct: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYI 53
Score = 43.2 bits (97), Expect = 0.006
Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVV-RRDGDWWTGRIGARTGIFPSNYVS 1053
A + + E G+L F G+ I V+ D +WW G +TG+FP NYV+
Sbjct: 163 ALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVT 211
Score = 35.9 bits (79), Expect = 0.95
Identities = 14/56 (25%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDGD--WWTGRIGARTGIFPSNYVSREAAP 1058
IA Y + ++ +L F+ G+ ++V+ + D W+ + + G P NY+ + P
Sbjct: 4 IAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHP 59
Score = 33.9 bits (74), Expect = 3.8
Identities = 17/55 (30%), Positives = 24/55 (43%), Gaps = 5/55 (9%)
Query: 1162 VQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
VQAL + +L +G + V +D WW+G Q G FP +YV
Sbjct: 161 VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHG-----QTGMFPRNYV 210
>L29511-1|AAC37549.1| 176|Homo sapiens growth factor receptor-bound
protein 3 protein.
Length = 176
Score = 55.2 bits (127), Expect = 1e-06
Identities = 25/52 (48%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVT 1300
V AL+ + Q EL F + D I V D S DP WW+G G G+FP NYVT
Sbjct: 120 VQALFDFDPQEDGELGFRRGDFIHVMDNS-DPNWWKGACHGQTGMFPRNYVT 170
Score = 48.0 bits (109), Expect = 2e-04
Identities = 20/52 (38%), Positives = 30/52 (57%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+ +A Y + A DELSF++ DI+ V + D W++ EL G G P NY+
Sbjct: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYI 53
Score = 43.2 bits (97), Expect = 0.006
Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVV-RRDGDWWTGRIGARTGIFPSNYVS 1053
A + + E G+L F G+ I V+ D +WW G +TG+FP NYV+
Sbjct: 122 ALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVT 170
Score = 35.9 bits (79), Expect = 0.95
Identities = 14/56 (25%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDGD--WWTGRIGARTGIFPSNYVSREAAP 1058
IA Y + ++ +L F+ G+ ++V+ + D W+ + + G P NY+ + P
Sbjct: 4 IAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHP 59
Score = 33.9 bits (74), Expect = 3.8
Identities = 17/55 (30%), Positives = 24/55 (43%), Gaps = 5/55 (9%)
Query: 1162 VQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
VQAL + +L +G + V +D WW+G Q G FP +YV
Sbjct: 120 VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHG-----QTGMFPRNYV 169
>CR541942-1|CAG46740.1| 217|Homo sapiens GRB2 protein.
Length = 217
Score = 55.2 bits (127), Expect = 1e-06
Identities = 25/52 (48%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVT 1300
V AL+ + Q EL F + D I V D S DP WW+G G G+FP NYVT
Sbjct: 161 VQALFDFDPQEDGELGFRRGDFIHVMDNS-DPNWWKGACHGQTGMFPRNYVT 211
Score = 48.0 bits (109), Expect = 2e-04
Identities = 20/52 (38%), Positives = 30/52 (57%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+ +A Y + A DELSF++ DI+ V + D W++ EL G G P NY+
Sbjct: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYI 53
Score = 43.2 bits (97), Expect = 0.006
Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVV-RRDGDWWTGRIGARTGIFPSNYVS 1053
A + + E G+L F G+ I V+ D +WW G +TG+FP NYV+
Sbjct: 163 ALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVT 211
Score = 35.9 bits (79), Expect = 0.95
Identities = 14/56 (25%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDGD--WWTGRIGARTGIFPSNYVSREAAP 1058
IA Y + ++ +L F+ G+ ++V+ + D W+ + + G P NY+ + P
Sbjct: 4 IAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHP 59
Score = 33.9 bits (74), Expect = 3.8
Identities = 17/55 (30%), Positives = 24/55 (43%), Gaps = 5/55 (9%)
Query: 1162 VQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
VQAL + +L +G + V +D WW+G Q G FP +YV
Sbjct: 161 VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHG-----QTGMFPRNYV 210
>CR541849-1|CAG46647.1| 330|Homo sapiens GRAP2 protein.
Length = 330
Score = 55.2 bits (127), Expect = 1e-06
Identities = 23/52 (44%), Positives = 32/52 (61%), Gaps = 1/52 (1%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
ALY + A DEL F +++ V D S +P+WW G L +GLFP+NYV +
Sbjct: 278 ALYDFEALEDDELGFHSGEVVEVLD-SSNPSWWTGRLHNKLGLFPANYVAPM 328
Score = 49.6 bits (113), Expect = 7e-05
Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 4/93 (4%)
Query: 964 GIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGE--FYIASYPYSSSEPGDLVFE 1021
G ++ + + LG + A + R ++PV ++ G + A Y + + E +L F
Sbjct: 235 GSLDINDGHCGTGLGSEMNAAL-MHRRHTDPVQLQAAGRVRWARALYDFEALEDDELGFH 293
Query: 1022 AGERIEVVRRDG-DWWTGRIGARTGIFPSNYVS 1053
+GE +EV+ WWTGR+ + G+FP+NYV+
Sbjct: 294 SGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVA 326
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/52 (30%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+ VA + +TA DELSF D++ + ++ W++ EL G P N++
Sbjct: 2 EAVAKFDFTASGEDELSFHTGDVLKILSNQEE--WFKAELGSQEGYVPKNFI 51
Score = 35.5 bits (78), Expect = 1.3
Identities = 10/48 (20%), Positives = 28/48 (58%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIFPSNYV 1052
+A + +++S +L F G+ ++++ +W+ +G++ G P N++
Sbjct: 4 VAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFI 51
>CR536524-1|CAG38761.1| 330|Homo sapiens GRAP2 protein.
Length = 330
Score = 55.2 bits (127), Expect = 1e-06
Identities = 23/52 (44%), Positives = 32/52 (61%), Gaps = 1/52 (1%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
ALY + A DEL F +++ V D S +P+WW G L +GLFP+NYV +
Sbjct: 278 ALYDFEALEDDELGFHSGEVVEVLD-SSNPSWWTGRLHNKLGLFPANYVAPM 328
Score = 49.6 bits (113), Expect = 7e-05
Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 4/93 (4%)
Query: 964 GIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGE--FYIASYPYSSSEPGDLVFE 1021
G ++ + + LG + A + R ++PV ++ G + A Y + + E +L F
Sbjct: 235 GSLDINDGHCGTGLGSEMNAAL-MHRRHTDPVQLQAAGRVRWARALYDFEALEDDELGFH 293
Query: 1022 AGERIEVVRRDG-DWWTGRIGARTGIFPSNYVS 1053
+GE +EV+ WWTGR+ + G+FP+NYV+
Sbjct: 294 SGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVA 326
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/52 (30%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+ VA + +TA DELSF D++ + ++ W++ EL G P N++
Sbjct: 2 EAVAKFDFTASGEDELSFHTGDVLKILSNQEE--WFKAELGSQEGYVPKNFI 51
Score = 35.5 bits (78), Expect = 1.3
Identities = 10/48 (20%), Positives = 28/48 (58%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIFPSNYV 1052
+A + +++S +L F G+ ++++ +W+ +G++ G P N++
Sbjct: 4 VAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFI 51
>CR456498-1|CAG30384.1| 330|Homo sapiens GRAP2 protein.
Length = 330
Score = 55.2 bits (127), Expect = 1e-06
Identities = 23/52 (44%), Positives = 32/52 (61%), Gaps = 1/52 (1%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
ALY + A DEL F +++ V D S +P+WW G L +GLFP+NYV +
Sbjct: 278 ALYDFEALEDDELGFHSGEVVEVLD-SSNPSWWTGRLHNKLGLFPANYVAPM 328
Score = 49.6 bits (113), Expect = 7e-05
Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 4/93 (4%)
Query: 964 GIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGE--FYIASYPYSSSEPGDLVFE 1021
G ++ + + LG + A + R ++PV ++ G + A Y + + E +L F
Sbjct: 235 GSLDINDGHCGTGLGSEMNAAL-MHRRHTDPVQLQAAGRVRWARALYDFEALEDDELGFH 293
Query: 1022 AGERIEVVRRDG-DWWTGRIGARTGIFPSNYVS 1053
+GE +EV+ WWTGR+ + G+FP+NYV+
Sbjct: 294 SGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVA 326
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/52 (30%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+ VA + +TA DELSF D++ + ++ W++ EL G P N++
Sbjct: 2 EAVAKFDFTASGEDELSFHTGDVLKILSNQEE--WFKAELGSQEGYVPKNFI 51
Score = 35.5 bits (78), Expect = 1.3
Identities = 10/48 (20%), Positives = 28/48 (58%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIFPSNYV 1052
+A + +++S +L F G+ ++++ +W+ +G++ G P N++
Sbjct: 4 VAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFI 51
>BC125107-1|AAI25108.1| 729|Homo sapiens SH3 domain containing ring
finger 2 protein.
Length = 729
Score = 55.2 bits (127), Expect = 1e-06
Identities = 42/137 (30%), Positives = 68/137 (49%), Gaps = 20/137 (14%)
Query: 1163 QALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSS 1222
+AL +Y +P L KG ++++R++ D W++GE+ N G FPAS V+V++
Sbjct: 131 KALCNYRGQNPGDLRFNKGDIILLRRQLDENWYQGEI-----NGISGNFPASSVEVIKQL 185
Query: 1223 GRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAW 1282
+ + + + DK ++N D L+F KDDII V R D W
Sbjct: 186 PQPPPLCRALYNFDLRGK------DK--------SENQDCLTFLKDDIITVISR-VDENW 230
Query: 1283 WQGELRGMVGLFPSNYV 1299
+G+L VG+FP +V
Sbjct: 231 AEGKLGDKVGIFPILFV 247
Score = 44.8 bits (101), Expect = 0.002
Identities = 27/72 (37%), Positives = 37/72 (51%), Gaps = 7/72 (9%)
Query: 1228 RTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGEL 1287
R P + MD +P + AL Y QN +L F K DII + R D W+QGE+
Sbjct: 115 RLVPNVRIHMDGVP------RAKALCNYRGQNPGDLRFNKGDIILLR-RQLDENWYQGEI 167
Query: 1288 RGMVGLFPSNYV 1299
G+ G FP++ V
Sbjct: 168 NGISGNFPASSV 179
Score = 43.6 bits (98), Expect = 0.005
Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 7/78 (8%)
Query: 982 PAVVDPGRT---VSEPVSVED-DGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWW- 1036
PA V PG + VS P S + ++A + YS+ P +L + GE + V+ + D W
Sbjct: 359 PAPVSPGHSTAVVSLPGSQQHLSANMFVALHSYSAHGPDELDLQKGEGVRVLGKCQDGWL 418
Query: 1037 --TGRIGARTGIFPSNYV 1052
+ R GIFP+NYV
Sbjct: 419 RGVSLVTGRVGIFPNNYV 436
Score = 43.2 bits (97), Expect = 0.006
Identities = 22/52 (42%), Positives = 32/52 (61%), Gaps = 3/52 (5%)
Query: 1250 VALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGE--LRGMVGLFPSNYV 1299
VAL+ Y+A DEL +K + + V + QD W +G + G VG+FP+NYV
Sbjct: 386 VALHSYSAHGPDELDLQKGEGVRVLGKCQD-GWLRGVSLVTGRVGIFPNNYV 436
Score = 41.5 bits (93), Expect = 0.019
Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 6/68 (8%)
Query: 1152 SVTGRRKH---EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQV 1208
S+ G ++H + AL SY+A P++L L KG+ + V K GW G GR V
Sbjct: 372 SLPGSQQHLSANMFVALHSYSAHGPDELDLQKGEGVRVLGKCQDGWLRGVSLVTGR---V 428
Query: 1209 GWFPASYV 1216
G FP +YV
Sbjct: 429 GIFPNNYV 436
Score = 34.3 bits (75), Expect = 2.9
Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 1010 YSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
Y PGDL F G+ I + R+ D +W+ G I +G FP++ V
Sbjct: 136 YRGQNPGDLRFNKGDIILLRRQLDENWYQGEINGISGNFPASSV 179
>BC125106-1|AAI25107.1| 729|Homo sapiens SH3 domain containing ring
finger 2 protein.
Length = 729
Score = 55.2 bits (127), Expect = 1e-06
Identities = 42/137 (30%), Positives = 68/137 (49%), Gaps = 20/137 (14%)
Query: 1163 QALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSS 1222
+AL +Y +P L KG ++++R++ D W++GE+ N G FPAS V+V++
Sbjct: 131 KALCNYRGQNPGDLRFNKGDIILLRRQLDENWYQGEI-----NGISGNFPASSVEVIKQL 185
Query: 1223 GRTSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAW 1282
+ + + + DK ++N D L+F KDDII V R D W
Sbjct: 186 PQPPPLCRALYNFDLRGK------DK--------SENQDCLTFLKDDIITVISR-VDENW 230
Query: 1283 WQGELRGMVGLFPSNYV 1299
+G+L VG+FP +V
Sbjct: 231 AEGKLGDKVGIFPILFV 247
Score = 44.8 bits (101), Expect = 0.002
Identities = 27/72 (37%), Positives = 37/72 (51%), Gaps = 7/72 (9%)
Query: 1228 RTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGEL 1287
R P + MD +P + AL Y QN +L F K DII + R D W+QGE+
Sbjct: 115 RLVPNVRIHMDGVP------RAKALCNYRGQNPGDLRFNKGDIILLR-RQLDENWYQGEI 167
Query: 1288 RGMVGLFPSNYV 1299
G+ G FP++ V
Sbjct: 168 NGISGNFPASSV 179
Score = 43.6 bits (98), Expect = 0.005
Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 7/78 (8%)
Query: 982 PAVVDPGRT---VSEPVSVED-DGEFYIASYPYSSSEPGDLVFEAGERIEVVRRDGDWW- 1036
PA V PG + VS P S + ++A + YS+ P +L + GE + V+ + D W
Sbjct: 359 PAPVSPGHSTAVVSLPGSQQHLSANMFVALHSYSAHGPDELDLQKGEGVRVLGKCQDGWL 418
Query: 1037 --TGRIGARTGIFPSNYV 1052
+ R GIFP+NYV
Sbjct: 419 RGVSLVTGRVGIFPNNYV 436
Score = 43.2 bits (97), Expect = 0.006
Identities = 22/52 (42%), Positives = 32/52 (61%), Gaps = 3/52 (5%)
Query: 1250 VALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGE--LRGMVGLFPSNYV 1299
VAL+ Y+A DEL +K + + V + QD W +G + G VG+FP+NYV
Sbjct: 386 VALHSYSAHGPDELDLQKGEGVRVLGKCQD-GWLRGVSLVTGRVGIFPNNYV 436
Score = 41.5 bits (93), Expect = 0.019
Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 6/68 (8%)
Query: 1152 SVTGRRKH---EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQV 1208
S+ G ++H + AL SY+A P++L L KG+ + V K GW G GR V
Sbjct: 372 SLPGSQQHLSANMFVALHSYSAHGPDELDLQKGEGVRVLGKCQDGWLRGVSLVTGR---V 428
Query: 1209 GWFPASYV 1216
G FP +YV
Sbjct: 429 GIFPNNYV 436
Score = 34.3 bits (75), Expect = 2.9
Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 1010 YSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
Y PGDL F G+ I + R+ D +W+ G I +G FP++ V
Sbjct: 136 YRGQNPGDLRFNKGDIILLRRQLDENWYQGEINGISGNFPASSV 179
>BC032468-1|AAH32468.1| 104|Homo sapiens DKFZp434D0215 protein
protein.
Length = 104
Score = 55.2 bits (127), Expect = 1e-06
Identities = 41/114 (35%), Positives = 56/114 (49%), Gaps = 19/114 (16%)
Query: 1186 VRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGRTSGRTTPVLSSKMDALPTETV 1245
+ ++ DS W G LQ +R+ G FPA +V R P + M A+ +
Sbjct: 4 ILERLDSDWCRGRLQ----DRE-GIFPAVFV-----------RPCPAEAKSMLAIVPKG- 46
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
K ALY + +N DELSF+ DII + S D W GEL G G+FP NY+
Sbjct: 47 -RKAKALYDFRGENEDELSFKAGDIITELE-SVDDDWMSGELMGKSGIFPKNYI 98
Score = 41.1 bits (92), Expect = 0.025
Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 976 DLGGALPAV-VDPGRTVSEPV-SVEDDGEFYIASYPYSSSEPGDLVFEAGERI-EVVRRD 1032
D G PAV V P ++ + ++ G A Y + +L F+AG+ I E+ D
Sbjct: 19 DREGIFPAVFVRPCPAEAKSMLAIVPKGRKAKALYDFRGENEDELSFKAGDIITELESVD 78
Query: 1033 GDWWTGRIGARTGIFPSNYV 1052
DW +G + ++GIFP NY+
Sbjct: 79 DDWMSGELMGKSGIFPKNYI 98
>BC026002-1|AAH26002.1| 330|Homo sapiens GRAP2 protein protein.
Length = 330
Score = 55.2 bits (127), Expect = 1e-06
Identities = 23/52 (44%), Positives = 32/52 (61%), Gaps = 1/52 (1%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
ALY + A DEL F +++ V D S +P+WW G L +GLFP+NYV +
Sbjct: 278 ALYDFEALEDDELGFHSGEVVEVLD-SSNPSWWTGRLHNKLGLFPANYVAPM 328
Score = 49.6 bits (113), Expect = 7e-05
Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 4/93 (4%)
Query: 964 GIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGE--FYIASYPYSSSEPGDLVFE 1021
G ++ + + LG + A + R ++PV ++ G + A Y + + E +L F
Sbjct: 235 GSLDINDGHCGTGLGSEMNAAL-MHRRHTDPVQLQAAGRVRWARALYDFEALEDDELGFH 293
Query: 1022 AGERIEVVRRDG-DWWTGRIGARTGIFPSNYVS 1053
+GE +EV+ WWTGR+ + G+FP+NYV+
Sbjct: 294 SGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVA 326
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/52 (30%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+ VA + +TA DELSF D++ + ++ W++ EL G P N++
Sbjct: 2 EAVAKFDFTASGEDELSFHTGDVLKILSNQEE--WFKAELGSQEGYVPKNFI 51
Score = 35.5 bits (78), Expect = 1.3
Identities = 10/48 (20%), Positives = 28/48 (58%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIFPSNYV 1052
+A + +++S +L F G+ ++++ +W+ +G++ G P N++
Sbjct: 4 VAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFI 51
>BC025692-1|AAH25692.1| 330|Homo sapiens GRB2-related adaptor protein
2 protein.
Length = 330
Score = 55.2 bits (127), Expect = 1e-06
Identities = 23/52 (44%), Positives = 32/52 (61%), Gaps = 1/52 (1%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
ALY + A DEL F +++ V D S +P+WW G L +GLFP+NYV +
Sbjct: 278 ALYDFEALEDDELGFHSGEVVEVLD-SSNPSWWTGRLHNKLGLFPANYVAPM 328
Score = 49.6 bits (113), Expect = 7e-05
Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 4/93 (4%)
Query: 964 GIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGE--FYIASYPYSSSEPGDLVFE 1021
G ++ + + LG + A + R ++PV ++ G + A Y + + E +L F
Sbjct: 235 GSLDINDGHCGTGLGSEMNAAL-MHRRHTDPVQLQAAGRVRWARALYDFEALEDDELGFH 293
Query: 1022 AGERIEVVRRDG-DWWTGRIGARTGIFPSNYVS 1053
+GE +EV+ WWTGR+ + G+FP+NYV+
Sbjct: 294 SGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVA 326
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/52 (30%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+ VA + +TA DELSF D++ + ++ W++ EL G P N++
Sbjct: 2 EAVAKFDFTASGEDELSFHTGDVLKILSNQEE--WFKAELGSQEGYVPKNFI 51
Score = 35.5 bits (78), Expect = 1.3
Identities = 10/48 (20%), Positives = 28/48 (58%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIFPSNYV 1052
+A + +++S +L F G+ ++++ +W+ +G++ G P N++
Sbjct: 4 VAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFI 51
>BC024254-1|AAH24254.1| 476|Homo sapiens abl-interactor 1 protein.
Length = 476
Score = 55.2 bits (127), Expect = 1e-06
Identities = 26/59 (44%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
I+KVVA+Y YT DELSF + II V ++ D W++G + GLFP NYV +++
Sbjct: 416 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD-GWYEGVCNRVTGLFPGNYVESIMH 473
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS M+G ++ V KK D GW+EG NR G FP +YV+
Sbjct: 417 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 469
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 1002 EFYIASYPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYV 1052
E +A Y Y+ + +L F G I V++++ D W+ G TG+FP NYV
Sbjct: 417 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYV 468
>BC000631-1|AAH00631.1| 217|Homo sapiens growth factor receptor-bound
protein 2 protein.
Length = 217
Score = 55.2 bits (127), Expect = 1e-06
Identities = 25/52 (48%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Query: 1249 VVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVT 1300
V AL+ + Q EL F + D I V D S DP WW+G G G+FP NYVT
Sbjct: 161 VQALFDFDPQEDGELGFRRGDFIHVMDNS-DPNWWKGACHGQTGMFPRNYVT 211
Score = 48.0 bits (109), Expect = 2e-04
Identities = 20/52 (38%), Positives = 30/52 (57%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+ +A Y + A DELSF++ DI+ V + D W++ EL G G P NY+
Sbjct: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYI 53
Score = 43.2 bits (97), Expect = 0.006
Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 1006 ASYPYSSSEPGDLVFEAGERIEVV-RRDGDWWTGRIGARTGIFPSNYVS 1053
A + + E G+L F G+ I V+ D +WW G +TG+FP NYV+
Sbjct: 163 ALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVT 211
Score = 35.9 bits (79), Expect = 0.95
Identities = 14/56 (25%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDGD--WWTGRIGARTGIFPSNYVSREAAP 1058
IA Y + ++ +L F+ G+ ++V+ + D W+ + + G P NY+ + P
Sbjct: 4 IAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHP 59
Score = 33.9 bits (74), Expect = 3.8
Identities = 17/55 (30%), Positives = 24/55 (43%), Gaps = 5/55 (9%)
Query: 1162 VQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYV 1216
VQAL + +L +G + V +D WW+G Q G FP +YV
Sbjct: 161 VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHG-----QTGMFPRNYV 210
>AY196211-1|AAP34307.1| 1577|Homo sapiens TUBA protein.
Length = 1577
Score = 55.2 bits (127), Expect = 1e-06
Identities = 39/138 (28%), Positives = 69/138 (50%), Gaps = 9/138 (6%)
Query: 1165 LASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGR 1224
+ +T+ + L L +G L+++ +GW +G R G+FP+S V+ L S +
Sbjct: 74 ICEFTSQELDNLPLHRGDLVILDGIPTAGWLQGRSCWGAR----GFFPSSCVRELCLSSQ 129
Query: 1225 TSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQ 1284
+ + S + +P E + + AL +AQ +EL F + D+I + +P W++
Sbjct: 130 SRQWHS---QSALFQIP-EYSMGQARALMGLSAQLDEELDFREGDVITIIG-VPEPGWFE 184
Query: 1285 GELRGMVGLFPSNYVTKL 1302
GEL G G+FP +V L
Sbjct: 185 GELEGRRGIFPEGFVELL 202
Score = 53.2 bits (122), Expect = 6e-06
Identities = 44/153 (28%), Positives = 73/153 (47%), Gaps = 22/153 (14%)
Query: 1163 QALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVL--- 1219
+AL +A E+L +G ++ + + GW+EGEL+ GR G FP +V++L
Sbjct: 151 RALMGLSAQLDEELDFREGDVITIIGVPEPGWFEGELE--GRR---GIFPEGFVELLGPL 205
Query: 1220 ---QSSGRTSGRTTPVLSSKMDALPTETVI----DKV------VALYPYTAQNADELSFE 1266
S + + +++ ++D E I D+ VALY + A +EL FE
Sbjct: 206 RTVDESVSSGNQDDCIVNGEVDTPVGEEEIGPDEDEEEPGTYGVALYRFQALEPNELDFE 265
Query: 1267 KDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
D I + +D W +G L+G G+FP +V
Sbjct: 266 VGDKIRILATLED-GWLEGSLKGRTGIFPYRFV 297
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/56 (35%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 998 EDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
E+ G + +A Y + + EP +L FE G++I ++ + W G + RTGIFP +V
Sbjct: 242 EEPGTYGVALYRFQALEPNELDFEVGDKIRILATLEDGWLEGSLKGRTGIFPYRFV 297
Score = 40.7 bits (91), Expect = 0.034
Identities = 18/69 (26%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
Query: 992 SEPVSVEDDG-EFYIASYPYSSSEPGDLVFEAGERIEV-----VRRDGDWWTGRIGARTG 1045
+EP E +G + Y A Y + + P +L A +++++ V + +WW + + G
Sbjct: 1505 TEPDGSEAEGNQVYFAVYTFKARNPNELSVSANQKLKILEFKDVTGNTEWWLAEVNGKKG 1564
Query: 1046 IFPSNYVSR 1054
PSNY+ +
Sbjct: 1565 YVPSNYIRK 1573
Score = 40.7 bits (91), Expect = 0.034
Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 3/54 (5%)
Query: 1251 ALYPYTAQNADELSF---EKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
A+Y + A+N +ELS +K I+ D + + WW E+ G G PSNY+ K
Sbjct: 1520 AVYTFKARNPNELSVSANQKLKILEFKDVTGNTEWWLAEVNGKKGYVPSNYIRK 1573
>AY069959-1|AAL58573.1| 330|Homo sapiens Mona protein.
Length = 330
Score = 55.2 bits (127), Expect = 1e-06
Identities = 23/52 (44%), Positives = 32/52 (61%), Gaps = 1/52 (1%)
Query: 1251 ALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKL 1302
ALY + A DEL F +++ V D S +P+WW G L +GLFP+NYV +
Sbjct: 278 ALYDFEALEDDELGFHSGEVVEVLD-SSNPSWWTGRLHNKLGLFPANYVAPM 328
Score = 49.6 bits (113), Expect = 7e-05
Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 4/93 (4%)
Query: 964 GIAEVPEQEATSDLGGALPAVVDPGRTVSEPVSVEDDGE--FYIASYPYSSSEPGDLVFE 1021
G ++ + + LG + A + R ++PV ++ G + A Y + + E +L F
Sbjct: 235 GSLDINDGHCGTGLGSEMNAAL-MHRRHTDPVQLQAAGRVRWARALYDFEALEDDELGFH 293
Query: 1022 AGERIEVVRRDG-DWWTGRIGARTGIFPSNYVS 1053
+GE +EV+ WWTGR+ + G+FP+NYV+
Sbjct: 294 SGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVA 326
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/52 (30%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 1248 KVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
+ VA + +TA DELSF D++ + ++ W++ EL G P N++
Sbjct: 2 EAVAKFDFTASGEDELSFHTGDVLKILSNQEE--WFKAELGSQEGYVPKNFI 51
Score = 35.5 bits (78), Expect = 1.3
Identities = 10/48 (20%), Positives = 28/48 (58%)
Query: 1005 IASYPYSSSEPGDLVFEAGERIEVVRRDGDWWTGRIGARTGIFPSNYV 1052
+A + +++S +L F G+ ++++ +W+ +G++ G P N++
Sbjct: 4 VAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFI 51
>AL627434-2|CAI13197.1| 1601|Homo sapiens novel protein protein.
Length = 1601
Score = 55.2 bits (127), Expect = 1e-06
Identities = 39/138 (28%), Positives = 69/138 (50%), Gaps = 9/138 (6%)
Query: 1165 LASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGR 1224
+ +T+ + L L +G L+++ +GW +G R G+FP+S V+ L S +
Sbjct: 74 ICEFTSQELDNLPLHRGDLVILDGIPTAGWLQGRSCWGAR----GFFPSSCVRELCLSSQ 129
Query: 1225 TSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQ 1284
+ + S + +P E + + AL +AQ +EL F + D+I + +P W++
Sbjct: 130 SRQWHS---QSALFQIP-EYSMGQARALMGLSAQLDEELDFREGDVITIIG-VPEPGWFE 184
Query: 1285 GELRGMVGLFPSNYVTKL 1302
GEL G G+FP +V L
Sbjct: 185 GELEGRRGIFPEGFVELL 202
Score = 53.2 bits (122), Expect = 6e-06
Identities = 44/153 (28%), Positives = 73/153 (47%), Gaps = 22/153 (14%)
Query: 1163 QALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVL--- 1219
+AL +A E+L +G ++ + + GW+EGEL+ GR G FP +V++L
Sbjct: 151 RALMGLSAQLDEELDFREGDVITIIGVPEPGWFEGELE--GRR---GIFPEGFVELLGPL 205
Query: 1220 ---QSSGRTSGRTTPVLSSKMDALPTETVI----DKV------VALYPYTAQNADELSFE 1266
S + + +++ ++D E I D+ VALY + A +EL FE
Sbjct: 206 RTVDESVSSGNQDDCIVNGEVDTPVGEEEIGPDEDEEEPGTYGVALYRFQALEPNELDFE 265
Query: 1267 KDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
D I + +D W +G L+G G+FP +V
Sbjct: 266 VGDKIRILATLED-GWLEGSLKGRTGIFPYRFV 297
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/56 (35%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 998 EDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
E+ G + +A Y + + EP +L FE G++I ++ + W G + RTGIFP +V
Sbjct: 242 EEPGTYGVALYRFQALEPNELDFEVGDKIRILATLEDGWLEGSLKGRTGIFPYRFV 297
Score = 40.7 bits (91), Expect = 0.034
Identities = 18/69 (26%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
Query: 992 SEPVSVEDDG-EFYIASYPYSSSEPGDLVFEAGERIEV-----VRRDGDWWTGRIGARTG 1045
+EP E +G + Y A Y + + P +L A +++++ V + +WW + + G
Sbjct: 1529 TEPDGSEAEGNQVYFAVYTFKARNPNELSVSANQKLKILEFKDVTGNTEWWLAEVNGKKG 1588
Query: 1046 IFPSNYVSR 1054
PSNY+ +
Sbjct: 1589 YVPSNYIRK 1597
Score = 40.7 bits (91), Expect = 0.034
Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 3/54 (5%)
Query: 1251 ALYPYTAQNADELSF---EKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
A+Y + A+N +ELS +K I+ D + + WW E+ G G PSNY+ K
Sbjct: 1544 AVYTFKARNPNELSVSANQKLKILEFKDVTGNTEWWLAEVNGKKGYVPSNYIRK 1597
>AL441886-1|CAI13076.1| 1601|Homo sapiens novel protein protein.
Length = 1601
Score = 55.2 bits (127), Expect = 1e-06
Identities = 39/138 (28%), Positives = 69/138 (50%), Gaps = 9/138 (6%)
Query: 1165 LASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGR 1224
+ +T+ + L L +G L+++ +GW +G R G+FP+S V+ L S +
Sbjct: 74 ICEFTSQELDNLPLHRGDLVILDGIPTAGWLQGRSCWGAR----GFFPSSCVRELCLSSQ 129
Query: 1225 TSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQ 1284
+ + S + +P E + + AL +AQ +EL F + D+I + +P W++
Sbjct: 130 SRQWHS---QSALFQIP-EYSMGQARALMGLSAQLDEELDFREGDVITIIG-VPEPGWFE 184
Query: 1285 GELRGMVGLFPSNYVTKL 1302
GEL G G+FP +V L
Sbjct: 185 GELEGRRGIFPEGFVELL 202
Score = 53.2 bits (122), Expect = 6e-06
Identities = 44/153 (28%), Positives = 73/153 (47%), Gaps = 22/153 (14%)
Query: 1163 QALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVL--- 1219
+AL +A E+L +G ++ + + GW+EGEL+ GR G FP +V++L
Sbjct: 151 RALMGLSAQLDEELDFREGDVITIIGVPEPGWFEGELE--GRR---GIFPEGFVELLGPL 205
Query: 1220 ---QSSGRTSGRTTPVLSSKMDALPTETVI----DKV------VALYPYTAQNADELSFE 1266
S + + +++ ++D E I D+ VALY + A +EL FE
Sbjct: 206 RTVDESVSSGNQDDCIVNGEVDTPVGEEEIGPDEDEEEPGTYGVALYRFQALEPNELDFE 265
Query: 1267 KDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
D I + +D W +G L+G G+FP +V
Sbjct: 266 VGDKIRILATLED-GWLEGSLKGRTGIFPYRFV 297
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/56 (35%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 998 EDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
E+ G + +A Y + + EP +L FE G++I ++ + W G + RTGIFP +V
Sbjct: 242 EEPGTYGVALYRFQALEPNELDFEVGDKIRILATLEDGWLEGSLKGRTGIFPYRFV 297
Score = 40.7 bits (91), Expect = 0.034
Identities = 18/69 (26%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
Query: 992 SEPVSVEDDG-EFYIASYPYSSSEPGDLVFEAGERIEV-----VRRDGDWWTGRIGARTG 1045
+EP E +G + Y A Y + + P +L A +++++ V + +WW + + G
Sbjct: 1529 TEPDGSEAEGNQVYFAVYTFKARNPNELSVSANQKLKILEFKDVTGNTEWWLAEVNGKKG 1588
Query: 1046 IFPSNYVSR 1054
PSNY+ +
Sbjct: 1589 YVPSNYIRK 1597
Score = 40.7 bits (91), Expect = 0.034
Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 3/54 (5%)
Query: 1251 ALYPYTAQNADELSF---EKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
A+Y + A+N +ELS +K I+ D + + WW E+ G G PSNY+ K
Sbjct: 1544 AVYTFKARNPNELSVSANQKLKILEFKDVTGNTEWWLAEVNGKKGYVPSNYIRK 1597
>AL392107-2|CAI11009.1| 1601|Homo sapiens novel protein protein.
Length = 1601
Score = 55.2 bits (127), Expect = 1e-06
Identities = 39/138 (28%), Positives = 69/138 (50%), Gaps = 9/138 (6%)
Query: 1165 LASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVLQSSGR 1224
+ +T+ + L L +G L+++ +GW +G R G+FP+S V+ L S +
Sbjct: 74 ICEFTSQELDNLPLHRGDLVILDGIPTAGWLQGRSCWGAR----GFFPSSCVRELCLSSQ 129
Query: 1225 TSGRTTPVLSSKMDALPTETVIDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQ 1284
+ + S + +P E + + AL +AQ +EL F + D+I + +P W++
Sbjct: 130 SRQWHS---QSALFQIP-EYSMGQARALMGLSAQLDEELDFREGDVITIIG-VPEPGWFE 184
Query: 1285 GELRGMVGLFPSNYVTKL 1302
GEL G G+FP +V L
Sbjct: 185 GELEGRRGIFPEGFVELL 202
Score = 53.2 bits (122), Expect = 6e-06
Identities = 44/153 (28%), Positives = 73/153 (47%), Gaps = 22/153 (14%)
Query: 1163 QALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVKVL--- 1219
+AL +A E+L +G ++ + + GW+EGEL+ GR G FP +V++L
Sbjct: 151 RALMGLSAQLDEELDFREGDVITIIGVPEPGWFEGELE--GRR---GIFPEGFVELLGPL 205
Query: 1220 ---QSSGRTSGRTTPVLSSKMDALPTETVI----DKV------VALYPYTAQNADELSFE 1266
S + + +++ ++D E I D+ VALY + A +EL FE
Sbjct: 206 RTVDESVSSGNQDDCIVNGEVDTPVGEEEIGPDEDEEEPGTYGVALYRFQALEPNELDFE 265
Query: 1267 KDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYV 1299
D I + +D W +G L+G G+FP +V
Sbjct: 266 VGDKIRILATLED-GWLEGSLKGRTGIFPYRFV 297
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/56 (35%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 998 EDDGEFYIASYPYSSSEPGDLVFEAGERIEVVRR-DGDWWTGRIGARTGIFPSNYV 1052
E+ G + +A Y + + EP +L FE G++I ++ + W G + RTGIFP +V
Sbjct: 242 EEPGTYGVALYRFQALEPNELDFEVGDKIRILATLEDGWLEGSLKGRTGIFPYRFV 297
Score = 40.7 bits (91), Expect = 0.034
Identities = 18/69 (26%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
Query: 992 SEPVSVEDDG-EFYIASYPYSSSEPGDLVFEAGERIEV-----VRRDGDWWTGRIGARTG 1045
+EP E +G + Y A Y + + P +L A +++++ V + +WW + + G
Sbjct: 1529 TEPDGSEAEGNQVYFAVYTFKARNPNELSVSANQKLKILEFKDVTGNTEWWLAEVNGKKG 1588
Query: 1046 IFPSNYVSR 1054
PSNY+ +
Sbjct: 1589 YVPSNYIRK 1597
Score = 40.7 bits (91), Expect = 0.034
Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 3/54 (5%)
Query: 1251 ALYPYTAQNADELSF---EKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTK 1301
A+Y + A+N +ELS +K I+ D + + WW E+ G G PSNY+ K
Sbjct: 1544 AVYTFKARNPNELSVSANQKLKILEFKDVTGNTEWWLAEVNGKKGYVPSNYIRK 1597
>AL390961-8|CAI17274.1| 476|Homo sapiens spectrin SH3 domain binding
protein 1 protein.
Length = 476
Score = 55.2 bits (127), Expect = 1e-06
Identities = 26/59 (44%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
I+KVVA+Y YT DELSF + II V ++ D W++G + GLFP NYV +++
Sbjct: 416 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD-GWYEGVCNRVTGLFPGNYVESIMH 473
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS M+G ++ V KK D GW+EG NR G FP +YV+
Sbjct: 417 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 469
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 1002 EFYIASYPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYV 1052
E +A Y Y+ + +L F G I V++++ D W+ G TG+FP NYV
Sbjct: 417 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYV 468
>AL390961-7|CAI17277.1| 480|Homo sapiens spectrin SH3 domain binding
protein 1 protein.
Length = 480
Score = 55.2 bits (127), Expect = 1e-06
Identities = 26/59 (44%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
I+KVVA+Y YT DELSF + II V ++ D W++G + GLFP NYV +++
Sbjct: 420 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD-GWYEGVCNRVTGLFPGNYVESIMH 477
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS M+G ++ V KK D GW+EG NR G FP +YV+
Sbjct: 421 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 473
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 1002 EFYIASYPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYV 1052
E +A Y Y+ + +L F G I V++++ D W+ G TG+FP NYV
Sbjct: 421 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYV 472
>AL390961-6|CAI17276.1| 481|Homo sapiens spectrin SH3 domain binding
protein 1 protein.
Length = 481
Score = 55.2 bits (127), Expect = 1e-06
Identities = 26/59 (44%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
I+KVVA+Y YT DELSF + II V ++ D W++G + GLFP NYV +++
Sbjct: 421 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD-GWYEGVCNRVTGLFPGNYVESIMH 478
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS M+G ++ V KK D GW+EG NR G FP +YV+
Sbjct: 422 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 474
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 1002 EFYIASYPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYV 1052
E +A Y Y+ + +L F G I V++++ D W+ G TG+FP NYV
Sbjct: 422 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYV 473
>AL390961-5|CAI17275.1| 508|Homo sapiens spectrin SH3 domain binding
protein 1 protein.
Length = 508
Score = 55.2 bits (127), Expect = 1e-06
Identities = 26/59 (44%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
I+KVVA+Y YT DELSF + II V ++ D W++G + GLFP NYV +++
Sbjct: 448 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD-GWYEGVCNRVTGLFPGNYVESIMH 505
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS M+G ++ V KK D GW+EG NR G FP +YV+
Sbjct: 449 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 501
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 1002 EFYIASYPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYV 1052
E +A Y Y+ + +L F G I V++++ D W+ G TG+FP NYV
Sbjct: 449 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYV 500
>AL390961-4|CAI17273.1| 475|Homo sapiens spectrin SH3 domain binding
protein 1 protein.
Length = 475
Score = 55.2 bits (127), Expect = 1e-06
Identities = 26/59 (44%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
I+KVVA+Y YT DELSF + II V ++ D W++G + GLFP NYV +++
Sbjct: 415 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD-GWYEGVCNRVTGLFPGNYVESIMH 472
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS M+G ++ V KK D GW+EG NR G FP +YV+
Sbjct: 416 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 468
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 1002 EFYIASYPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYV 1052
E +A Y Y+ + +L F G I V++++ D W+ G TG+FP NYV
Sbjct: 416 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYV 467
>AL390961-3|CAI17272.1| 446|Homo sapiens spectrin SH3 domain binding
protein 1 protein.
Length = 446
Score = 55.2 bits (127), Expect = 1e-06
Identities = 26/59 (44%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
I+KVVA+Y YT DELSF + II V ++ D W++G + GLFP NYV +++
Sbjct: 386 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD-GWYEGVCNRVTGLFPGNYVESIMH 443
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS M+G ++ V KK D GW+EG NR G FP +YV+
Sbjct: 387 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 439
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 1002 EFYIASYPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYV 1052
E +A Y Y+ + +L F G I V++++ D W+ G TG+FP NYV
Sbjct: 387 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYV 438
>AL390961-2|CAI17279.1| 451|Homo sapiens spectrin SH3 domain binding
protein 1 protein.
Length = 451
Score = 55.2 bits (127), Expect = 1e-06
Identities = 26/59 (44%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
I+KVVA+Y YT DELSF + II V ++ D W++G + GLFP NYV +++
Sbjct: 391 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD-GWYEGVCNRVTGLFPGNYVESIMH 448
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS M+G ++ V KK D GW+EG NR G FP +YV+
Sbjct: 392 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 444
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 1002 EFYIASYPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYV 1052
E +A Y Y+ + +L F G I V++++ D W+ G TG+FP NYV
Sbjct: 392 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYV 443
>AL390961-1|CAI17278.1| 452|Homo sapiens spectrin SH3 domain binding
protein 1 protein.
Length = 452
Score = 55.2 bits (127), Expect = 1e-06
Identities = 26/59 (44%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
I+KVVA+Y YT DELSF + II V ++ D W++G + GLFP NYV +++
Sbjct: 392 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD-GWYEGVCNRVTGLFPGNYVESIMH 449
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS M+G ++ V KK D GW+EG NR G FP +YV+
Sbjct: 393 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 445
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 1002 EFYIASYPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYV 1052
E +A Y Y+ + +L F G I V++++ D W+ G TG+FP NYV
Sbjct: 393 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYV 444
>AL139404-8|CAH73116.1| 452|Homo sapiens spectrin SH3 domain binding
protein 1 protein.
Length = 452
Score = 55.2 bits (127), Expect = 1e-06
Identities = 26/59 (44%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
I+KVVA+Y YT DELSF + II V ++ D W++G + GLFP NYV +++
Sbjct: 392 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD-GWYEGVCNRVTGLFPGNYVESIMH 449
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS M+G ++ V KK D GW+EG NR G FP +YV+
Sbjct: 393 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 445
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 1002 EFYIASYPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYV 1052
E +A Y Y+ + +L F G I V++++ D W+ G TG+FP NYV
Sbjct: 393 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYV 444
>AL139404-7|CAH73115.1| 476|Homo sapiens spectrin SH3 domain binding
protein 1 protein.
Length = 476
Score = 55.2 bits (127), Expect = 1e-06
Identities = 26/59 (44%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
I+KVVA+Y YT DELSF + II V ++ D W++G + GLFP NYV +++
Sbjct: 416 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD-GWYEGVCNRVTGLFPGNYVESIMH 473
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS M+G ++ V KK D GW+EG NR G FP +YV+
Sbjct: 417 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 469
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 1002 EFYIASYPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYV 1052
E +A Y Y+ + +L F G I V++++ D W+ G TG+FP NYV
Sbjct: 417 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYV 468
>AL139404-6|CAH73114.1| 480|Homo sapiens spectrin SH3 domain binding
protein 1 protein.
Length = 480
Score = 55.2 bits (127), Expect = 1e-06
Identities = 26/59 (44%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
I+KVVA+Y YT DELSF + II V ++ D W++G + GLFP NYV +++
Sbjct: 420 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD-GWYEGVCNRVTGLFPGNYVESIMH 477
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS M+G ++ V KK D GW+EG NR G FP +YV+
Sbjct: 421 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 473
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 1002 EFYIASYPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYV 1052
E +A Y Y+ + +L F G I V++++ D W+ G TG+FP NYV
Sbjct: 421 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYV 472
>AL139404-5|CAH73113.1| 481|Homo sapiens spectrin SH3 domain binding
protein 1 protein.
Length = 481
Score = 55.2 bits (127), Expect = 1e-06
Identities = 26/59 (44%), Positives = 37/59 (62%), Gaps = 1/59 (1%)
Query: 1246 IDKVVALYPYTAQNADELSFEKDDIIAVTDRSQDPAWWQGELRGMVGLFPSNYVTKLVN 1304
I+KVVA+Y YT DELSF + II V ++ D W++G + GLFP NYV +++
Sbjct: 421 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD-GWYEGVCNRVTGLFPGNYVESIMH 478
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/58 (41%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 1160 EIVQALASYTATSPEQLSLMKGQLLVVRKKADSGWWEGELQAKGRNRQVGWFPASYVK 1217
E V A+ YT ++LS M+G ++ V KK D GW+EG NR G FP +YV+
Sbjct: 422 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVC-----NRVTGLFPGNYVE 474
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 1002 EFYIASYPYSSSEPGDLVFEAGERIEVVRRDGD-WWTGRIGARTGIFPSNYV 1052
E +A Y Y+ + +L F G I V++++ D W+ G TG+FP NYV
Sbjct: 422 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYV 473
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.313 0.129 0.378
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 176,195,419
Number of Sequences: 224733
Number of extensions: 7388903
Number of successful extensions: 33015
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 643
Number of HSP's successfully gapped in prelim test: 724
Number of HSP's that attempted gapping in prelim test: 26946
Number of HSP's gapped (non-prelim): 5428
length of query: 1304
length of database: 73,234,838
effective HSP length: 99
effective length of query: 1205
effective length of database: 50,986,271
effective search space: 61438456555
effective search space used: 61438456555
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.9 bits)
S2: 71 (32.7 bits)
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