Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001650-TA|BGIBMGA001650-PA|IPR001577|Peptidase M8,
leishmanolysin
(568 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ312398-1|CAC42882.1| 640|Homo sapiens leishmanolysin-like pep... 485 e-136
AJ312399-1|CAC42883.1| 655|Homo sapiens leishmanolysin-like pep... 259 2e-68
AF471206-1|AAQ05381.1| 119|Homo sapiens Ig heavy chain variable... 35 0.89
BC128390-1|AAI28391.1| 1682|Homo sapiens ADAMTSL3 protein protein. 32 4.7
BC128389-1|AAI28390.1| 1691|Homo sapiens ADAMTS-like 3 protein. 32 4.7
AF237652-1|AAK15041.1| 766|Homo sapiens a disintegrin-like and ... 32 4.7
AB033059-1|BAA86547.1| 1023|Homo sapiens KIAA1233 protein protein. 32 4.7
U53446-1|AAA98975.1| 770|Homo sapiens DOC-2 protein. 31 8.3
U39050-1|AAC50824.1| 770|Homo sapiens DOC-2 protein. 31 8.3
BC003064-1|AAH03064.1| 770|Homo sapiens disabled homolog 2, mit... 31 8.3
AF205890-1|AAF23161.1| 770|Homo sapiens disabled-2 protein. 31 8.3
AF188298-1|AAF05540.1| 749|Homo sapiens disabled 2 p93 protein. 31 8.3
>AJ312398-1|CAC42882.1| 640|Homo sapiens leishmanolysin-like
peptidase, variant 2 protein.
Length = 640
Score = 485 bits (1195), Expect = e-136
Identities = 227/482 (47%), Positives = 307/482 (63%), Gaps = 17/482 (3%)
Query: 82 GVKDTDFMLYVSAVETERCRRGLTVAYASHCQQESALDRPVAGHANFCPAELSTKYRDLP 141
G+ D DF+LYV A+ TERC ++YA++CQQE+ +DRP+AG+AN CP +ST+ ++
Sbjct: 153 GISDADFVLYVGALATERCSHENIISYAAYCQQEANMDRPIAGYANLCPNMISTQPQEFV 212
Query: 142 SVLSTVKHEMLHALGFSVSLFAFYRDDNGEPLTERRPDTGNPPLDEELQIHKWSDRVVRN 201
+LSTVKHE++HALGFS LFAFY D +G PLT R D G PP + L +++WSD+VVR
Sbjct: 213 GMLSTVKHEVIHALGFSAGLFAFYHDKDGNPLTSRFAD-GLPPFNYSLGLYQWSDKVVRK 271
Query: 202 VTRKNWMIRGGYMER-TFHMMVTPRVVKEVREHFNCSELEGAELEDQGGDGTAMTHWEKR 260
V R W +R + R T +++VTPRVV+E R+HF+C LEG ELE+QGG GT + HWEKR
Sbjct: 272 VERL-WDVRDNKIVRHTVYLLVTPRVVEEARKHFDCPVLEGMELENQGGVGTELNHWEKR 330
Query: 261 VFENEAMTGTHTQNSVFSRITLAMMEDTGWYRADYSHATPLDWGKGLGCKFAMSSCKQWM 320
+ ENEAMTG+HTQN V SRITLA+MEDTGWY+A+YS A LDWG+G+GC F SCK W+
Sbjct: 331 LLENEAMTGSHTQNRVLSRITLALMEDTGWYKANYSMAEKLDWGRGMGCDFVRKSCKFWI 390
Query: 321 NLQRLRRRNPAPFCERIKGNPLRTECSPRRSAVVLCNLVRHDNLLPRAYQHFDILPNVPP 380
+ QR +R+ +P+C+ ++ NPL+ C + AV +CNL + LP+ YQ+FD L +P
Sbjct: 391 DQQRQKRQMLSPYCDTLRSNPLQLTCRQDQRAVAVCNLQKFPKPLPQEYQYFDELSGIPA 450
Query: 381 GQEAYYGGSVSLADYCPYLQEFTWRHKSVLIRGSRCSYEENTPKIDLNFALENYGQHSKC 440
YYGGSV +ADYCP+ QEF+W R S C EN P+I N+ E YG HS C
Sbjct: 451 EDLPYYGGSVEIADYCPFSQEFSWHLSGEYQRSSDCRILENQPEIFKNYGAEKYGPHSVC 510
Query: 441 FEHSDKVWEQKSCRQIREWQHWGSGCYKYKCDSGRLHIVVGNYTYTCFHAGQLLHIRIIK 500
+ + C + + WGSGCY+ C L + V + +Y C AGQ+L + I
Sbjct: 511 LIQK-SAFVMEKCEKKLSYPDWGSGCYQVSCSPQGLKVWVQDTSYLCSRAGQVLPVSIQM 569
Query: 501 NGWLHRGGVVCPPCRQVCGAEFAARSEYCKPGEEPLPPNL---YPNDFLACRASVIRPAI 557
NGW+H G ++CP C C E C P +P NL P D +C +S++
Sbjct: 570 NGWIHDGNLLCPSCWDFC--------ELCPPETDPPATNLTRALPLDLCSCSSSLV--VT 619
Query: 558 LW 559
LW
Sbjct: 620 LW 621
>AJ312399-1|CAC42883.1| 655|Homo sapiens leishmanolysin-like
peptidase, variant 1 protein.
Length = 655
Score = 259 bits (635), Expect = 2e-68
Identities = 120/209 (57%), Positives = 157/209 (75%), Gaps = 3/209 (1%)
Query: 82 GVKDTDFMLYVSAVETERCRRGLTVAYASHCQQESALDRPVAGHANFCPAELSTKYRDLP 141
G+ D DF+LYV A+ TERC ++YA++CQQE+ +DRP+AG+AN CP +ST+ ++
Sbjct: 205 GISDADFVLYVGALATERCSHENIISYAAYCQQEANMDRPIAGYANLCPNMISTQPQEFV 264
Query: 142 SVLSTVKHEMLHALGFSVSLFAFYRDDNGEPLTERRPDTGNPPLDEELQIHKWSDRVVRN 201
+LSTVKHE++HALGFS LFAFY D +G PLT R D G PP + L +++WSD+VVR
Sbjct: 265 GMLSTVKHEVIHALGFSAGLFAFYHDKDGNPLTSRFAD-GLPPFNYSLGLYQWSDKVVRK 323
Query: 202 VTRKNWMIRGGYMER-TFHMMVTPRVVKEVREHFNCSELEGAELEDQGGDGTAMTHWEKR 260
V R W +R + R T +++VTPRVV+E R+HF+C LEG ELE+QGG GT + HWEKR
Sbjct: 324 VERL-WDVRDNKIVRHTVYLLVTPRVVEEARKHFDCPVLEGMELENQGGVGTELNHWEKR 382
Query: 261 VFENEAMTGTHTQNSVFSRITLAMMEDTG 289
+ ENEAMTG+HTQN V SRITLA+MEDTG
Sbjct: 383 LLENEAMTGSHTQNRVLSRITLALMEDTG 411
Score = 177 bits (432), Expect = 6e-44
Identities = 87/236 (36%), Positives = 123/236 (52%), Gaps = 14/236 (5%)
Query: 327 RRNPAPFCERIKGNPLRTECSPRRSAVVLCNLVRHDNLLPRAYQHFDILPNVPPGQEAYY 386
R+ +P+C+ ++ NPL+ C + AV +CNL + LP+ YQ+FD L +P YY
Sbjct: 412 RQMLSPYCDTLRSNPLQLTCRQDQRAVAVCNLQKFPKPLPQEYQYFDELSGIPAEDLPYY 471
Query: 387 GGSVSLADYCPYLQEFTWRHKSVLIRGSRCSYEENTPKIDLNFALENYGQHSKCFEHSDK 446
GGSV +ADYCP+ QEF+W R S C EN P+I N+ E YG HS C
Sbjct: 472 GGSVEIADYCPFSQEFSWHLSGEYQRSSDCRILENQPEIFKNYGAEKYGPHSVCLIQK-S 530
Query: 447 VWEQKSCRQIREWQHWGSGCYKYKCDSGRLHIVVGNYTYTCFHAGQLLHIRIIKNGWLHR 506
+ + C + + WGSGCY+ C L + V + +Y C AGQ+L + I NGW+H
Sbjct: 531 AFVMEKCEKKLSYPDWGSGCYQVSCSPQGLKVWVQDTSYLCSRAGQVLPVSIQMNGWIHD 590
Query: 507 GGVVCPPCRQVCGAEFAARSEYCKPGEEPLPPNL---YPNDFLACRASVIRPAILW 559
G ++CP C C E C P +P NL P D +C +S++ LW
Sbjct: 591 GNLLCPSCWDFC--------ELCPPETDPPATNLTRALPLDLCSCSSSLV--VTLW 636
>AF471206-1|AAQ05381.1| 119|Homo sapiens Ig heavy chain variable
region, VH3 family protein.
Length = 119
Score = 34.7 bits (76), Expect = 0.89
Identities = 22/61 (36%), Positives = 31/61 (50%), Gaps = 4/61 (6%)
Query: 249 GDGTAMTHWEKRVFENEAMTGTHTQNSVFSRITLAMMEDTGWY--RADYSHATPLD-WGK 305
GDG+A ++ V ++ + QNSVF ++ EDT Y D SH P D WG+
Sbjct: 53 GDGSAK-YYVNSVRGRFTISRDNAQNSVFLQMNSLRAEDTAMYFCTRDPSHVVPFDYWGQ 111
Query: 306 G 306
G
Sbjct: 112 G 112
>BC128390-1|AAI28391.1| 1682|Homo sapiens ADAMTSL3 protein protein.
Length = 1682
Score = 32.3 bits (70), Expect = 4.7
Identities = 13/27 (48%), Positives = 13/27 (48%), Gaps = 1/27 (3%)
Query: 513 PCRQVCGAEFAARSEYC-KPGEEPLPP 538
PC CG R YC PGE P PP
Sbjct: 714 PCSATCGVGIQTRDVYCLHPGETPAPP 740
>BC128389-1|AAI28390.1| 1691|Homo sapiens ADAMTS-like 3 protein.
Length = 1691
Score = 32.3 bits (70), Expect = 4.7
Identities = 13/27 (48%), Positives = 13/27 (48%), Gaps = 1/27 (3%)
Query: 513 PCRQVCGAEFAARSEYC-KPGEEPLPP 538
PC CG R YC PGE P PP
Sbjct: 714 PCSATCGVGIQTRDVYCLHPGETPAPP 740
>AF237652-1|AAK15041.1| 766|Homo sapiens a disintegrin-like and
metalloprotease domain with thrombospondin type I motifs
protein.
Length = 766
Score = 32.3 bits (70), Expect = 4.7
Identities = 13/27 (48%), Positives = 13/27 (48%), Gaps = 1/27 (3%)
Query: 513 PCRQVCGAEFAARSEYC-KPGEEPLPP 538
PC CG R YC PGE P PP
Sbjct: 714 PCSATCGVGIQTRDVYCLHPGETPAPP 740
>AB033059-1|BAA86547.1| 1023|Homo sapiens KIAA1233 protein protein.
Length = 1023
Score = 32.3 bits (70), Expect = 4.7
Identities = 13/27 (48%), Positives = 13/27 (48%), Gaps = 1/27 (3%)
Query: 513 PCRQVCGAEFAARSEYC-KPGEEPLPP 538
PC CG R YC PGE P PP
Sbjct: 46 PCSATCGVGIQTRDVYCLHPGETPAPP 72
>U53446-1|AAA98975.1| 770|Homo sapiens DOC-2 protein.
Length = 770
Score = 31.5 bits (68), Expect = 8.3
Identities = 24/95 (25%), Positives = 41/95 (43%), Gaps = 4/95 (4%)
Query: 51 QPPPDDEPATEVSENNLDERSDVIDEDSEPVGVKDTDFMLY----VSAVETERCRRGLTV 106
QPPP P ++S + + D++ + V DF L V A + E+ G
Sbjct: 621 QPPPRAGPPKDISSDAFTALDPLGDKEIKDVKEMFKDFQLRQPPAVPARKGEQTSSGTLS 680
Query: 107 AYASHCQQESALDRPVAGHANFCPAELSTKYRDLP 141
A+AS+ + + + A H +F +L K + P
Sbjct: 681 AFASYFNSKVGIPQENADHDDFDANQLLNKINEPP 715
>U39050-1|AAC50824.1| 770|Homo sapiens DOC-2 protein.
Length = 770
Score = 31.5 bits (68), Expect = 8.3
Identities = 24/95 (25%), Positives = 41/95 (43%), Gaps = 4/95 (4%)
Query: 51 QPPPDDEPATEVSENNLDERSDVIDEDSEPVGVKDTDFMLY----VSAVETERCRRGLTV 106
QPPP P ++S + + D++ + V DF L V A + E+ G
Sbjct: 621 QPPPRAGPPKDISSDAFTALDPLGDKEIKDVKEMFKDFQLRQPPAVPARKGEQTSSGTLS 680
Query: 107 AYASHCQQESALDRPVAGHANFCPAELSTKYRDLP 141
A+AS+ + + + A H +F +L K + P
Sbjct: 681 AFASYFNSKVGIPQENADHDDFDANQLLNKINEPP 715
>BC003064-1|AAH03064.1| 770|Homo sapiens disabled homolog 2,
mitogen-responsive phosphoprotein (Drosophila) protein.
Length = 770
Score = 31.5 bits (68), Expect = 8.3
Identities = 24/95 (25%), Positives = 41/95 (43%), Gaps = 4/95 (4%)
Query: 51 QPPPDDEPATEVSENNLDERSDVIDEDSEPVGVKDTDFMLY----VSAVETERCRRGLTV 106
QPPP P ++S + + D++ + V DF L V A + E+ G
Sbjct: 621 QPPPRAGPPKDISSDAFTALDPLGDKEIKDVKEMFKDFQLRQPPAVPARKGEQTSSGTLS 680
Query: 107 AYASHCQQESALDRPVAGHANFCPAELSTKYRDLP 141
A+AS+ + + + A H +F +L K + P
Sbjct: 681 AFASYFNSKVGIPQENADHDDFDANQLLNKINEPP 715
>AF205890-1|AAF23161.1| 770|Homo sapiens disabled-2 protein.
Length = 770
Score = 31.5 bits (68), Expect = 8.3
Identities = 24/95 (25%), Positives = 41/95 (43%), Gaps = 4/95 (4%)
Query: 51 QPPPDDEPATEVSENNLDERSDVIDEDSEPVGVKDTDFMLY----VSAVETERCRRGLTV 106
QPPP P ++S + + D++ + V DF L V A + E+ G
Sbjct: 621 QPPPRAGPPKDISSDAFTALDPLGDKEIKDVKEMFKDFQLRQPPAVPARKGEQTSSGTLS 680
Query: 107 AYASHCQQESALDRPVAGHANFCPAELSTKYRDLP 141
A+AS+ + + + A H +F +L K + P
Sbjct: 681 AFASYFNSKVGIPQENADHDDFDANQLLNKINEPP 715
>AF188298-1|AAF05540.1| 749|Homo sapiens disabled 2 p93 protein.
Length = 749
Score = 31.5 bits (68), Expect = 8.3
Identities = 24/95 (25%), Positives = 41/95 (43%), Gaps = 4/95 (4%)
Query: 51 QPPPDDEPATEVSENNLDERSDVIDEDSEPVGVKDTDFMLY----VSAVETERCRRGLTV 106
QPPP P ++S + + D++ + V DF L V A + E+ G
Sbjct: 600 QPPPRAGPPKDISSDAFTALDPLGDKEIKDVKEMFKDFQLRQPPAVPARKGEQTSSGTLS 659
Query: 107 AYASHCQQESALDRPVAGHANFCPAELSTKYRDLP 141
A+AS+ + + + A H +F +L K + P
Sbjct: 660 AFASYFNSKVGIPQENADHDDFDANQLLNKINEPP 694
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.136 0.444
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 98,692,936
Number of Sequences: 224733
Number of extensions: 4572242
Number of successful extensions: 8825
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 8808
Number of HSP's gapped (non-prelim): 16
length of query: 568
length of database: 73,234,838
effective HSP length: 94
effective length of query: 474
effective length of database: 52,109,936
effective search space: 24700109664
effective search space used: 24700109664
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 68 (31.5 bits)
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