Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001648-TA|BGIBMGA001648-PA|IPR001015|Ferrochelatase
(329 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q967G9 Cluster: Ferrochelatase precursor; n=2; Endopter... 439 e-122
UniRef50_P22830 Cluster: Ferrochelatase, mitochondrial precursor... 359 6e-98
UniRef50_Q4SRE0 Cluster: Ferrochelatase; n=1; Tetraodon nigrovir... 310 3e-83
UniRef50_Q5AVC8 Cluster: Ferrochelatase; n=9; Fungi/Metazoa grou... 298 1e-79
UniRef50_A4RKF0 Cluster: Ferrochelatase; n=14; Pezizomycotina|Re... 287 3e-76
UniRef50_Q54IA8 Cluster: Ferrochelatase; n=1; Dictyostelium disc... 281 2e-74
UniRef50_P16622 Cluster: Ferrochelatase, mitochondrial precursor... 275 1e-72
UniRef50_UPI0001509D16 Cluster: ferrochelatase family protein; n... 255 1e-66
UniRef50_O04921 Cluster: Ferrochelatase-2, chloroplast precursor... 217 4e-55
UniRef50_P42044 Cluster: Ferrochelatase-2, chloroplast precursor... 215 1e-54
UniRef50_Q747F5 Cluster: Ferrochelatase; n=7; Desulfuromonadales... 211 2e-53
UniRef50_P42045 Cluster: Ferrochelatase-2, chloroplast precursor... 209 7e-53
UniRef50_UPI0000E4A92D Cluster: PREDICTED: similar to ferrochela... 204 2e-51
UniRef50_Q9ATG7 Cluster: Ferrochelatase; n=1; Polytomella sp. Pr... 200 3e-50
UniRef50_UPI00015BC7F1 Cluster: UPI00015BC7F1 related cluster; n... 184 2e-45
UniRef50_Q1K4G8 Cluster: Ferrochelatase; n=1; Desulfuromonas ace... 184 3e-45
UniRef50_O67083 Cluster: Ferrochelatase; n=1; Aquifex aeolicus|R... 184 3e-45
UniRef50_Q2RZ44 Cluster: Ferrochelatase; n=1; Salinibacter ruber... 184 4e-45
UniRef50_Q3A6H8 Cluster: Ferrochelatase; n=1; Pelobacter carbino... 183 5e-45
UniRef50_A3EV75 Cluster: Protoheme ferro-lyase; n=1; Leptospiril... 180 6e-44
UniRef50_Q6BFD7 Cluster: Ferrochelatase (EC 4.99.1.1), putative;... 178 2e-43
UniRef50_Q7VD58 Cluster: Ferrochelatase; n=20; Cyanobacteria|Rep... 176 6e-43
UniRef50_Q6APB0 Cluster: Ferrochelatase; n=1; Desulfotalea psych... 176 7e-43
UniRef50_Q2S1S2 Cluster: Ferrochelatase; n=1; Salinibacter ruber... 175 1e-42
UniRef50_Q1V1A3 Cluster: Ferrochelatase; n=2; Candidatus Pelagib... 173 7e-42
UniRef50_Q4UJN9 Cluster: Ferrochelatase; n=16; Rickettsiales|Rep... 171 2e-41
UniRef50_P57777 Cluster: Ferrochelatase; n=12; Alphaproteobacter... 166 6e-40
UniRef50_P56107 Cluster: Ferrochelatase; n=5; Helicobacteraceae|... 156 6e-37
UniRef50_A7H9E2 Cluster: Ferrochelatase; n=2; Anaeromyxobacter|R... 153 6e-36
UniRef50_Q2RN84 Cluster: Ferrochelatase; n=2; Alphaproteobacteri... 152 1e-35
UniRef50_Q0BWA5 Cluster: Ferrochelatase; n=1; Hyphomonas neptuni... 150 6e-35
UniRef50_Q5PA48 Cluster: Ferrochelatase; n=2; Anaplasma|Rep: Fer... 147 4e-34
UniRef50_A6QAW0 Cluster: Ferrochelatase; n=1; Sulfurovum sp. NBC... 146 7e-34
UniRef50_A6Q2Y9 Cluster: Ferrochelatase; n=2; Epsilonproteobacte... 141 3e-32
UniRef50_A7T926 Cluster: Predicted protein; n=1; Nematostella ve... 140 5e-32
UniRef50_Q5GRR7 Cluster: Ferrochelatase; n=1; Wolbachia endosymb... 139 1e-31
UniRef50_Q2GH68 Cluster: Ferrochelatase; n=3; canis group|Rep: F... 139 1e-31
UniRef50_Q2GCY1 Cluster: Ferrochelatase; n=1; Neorickettsia senn... 135 2e-30
UniRef50_Q9RV98 Cluster: Ferrochelatase; n=1; Deinococcus radiod... 124 2e-27
UniRef50_Q833G5 Cluster: Ferrochelatase; n=1; Enterococcus faeca... 121 3e-26
UniRef50_Q7VHH1 Cluster: Ferrochelatase; n=1; Helicobacter hepat... 118 2e-25
UniRef50_Q8GCV0 Cluster: Ferrochelatase; n=1; Leptospira biflexa... 118 3e-25
UniRef50_Q9PI08 Cluster: Ferrochelatase; n=16; Campylobacter|Rep... 118 3e-25
UniRef50_Q1NMT4 Cluster: Ferrochelatase; n=2; delta proteobacter... 116 1e-24
UniRef50_A6VXF8 Cluster: Ferrochelatase; n=1; Marinomonas sp. MW... 116 1e-24
UniRef50_A6DEA9 Cluster: Ferrochelatase; n=1; Caminibacter media... 113 8e-24
UniRef50_A5UU36 Cluster: Ferrochelatase; n=3; Chloroflexi (class... 113 8e-24
UniRef50_P37408 Cluster: Ferrochelatase; n=5; Enterobacteriaceae... 113 8e-24
UniRef50_P57874 Cluster: Ferrochelatase; n=1; Pasteurella multoc... 113 8e-24
UniRef50_UPI0000DAE46A Cluster: hypothetical protein Rgryl_01000... 111 3e-23
UniRef50_Q81TU9 Cluster: Ferrochelatase 2; n=76; Bacillales|Rep:... 111 3e-23
UniRef50_P43868 Cluster: Ferrochelatase; n=40; Bacteria|Rep: Fer... 110 6e-23
UniRef50_Q8FTB1 Cluster: Ferrochelatase; n=24; Actinomycetales|R... 108 2e-22
UniRef50_Q5YU18 Cluster: Ferrochelatase; n=14; Bacteria|Rep: Fer... 107 4e-22
UniRef50_Q5NFT3 Cluster: Ferrochelatase; n=11; Francisella tular... 107 4e-22
UniRef50_Q67T48 Cluster: Ferrochelatase; n=1; Symbiobacterium th... 106 9e-22
UniRef50_P43413 Cluster: Ferrochelatase; n=28; Gammaproteobacter... 105 1e-21
UniRef50_Q5QVZ8 Cluster: Ferrochelatase; n=17; Gammaproteobacter... 103 6e-21
UniRef50_Q5FSJ9 Cluster: Ferrochelatase; n=1; Gluconobacter oxyd... 103 8e-21
UniRef50_Q03Z41 Cluster: Ferrochelatase; n=1; Leuconostoc mesent... 102 1e-20
UniRef50_A5EXB1 Cluster: Ferrochelatase; n=1; Dichelobacter nodo... 102 1e-20
UniRef50_Q8EBZ7 Cluster: Ferrochelatase 2; n=48; Proteobacteria|... 102 1e-20
UniRef50_Q2BIY0 Cluster: Ferrochelatase; n=2; Gammaproteobacteri... 101 2e-20
UniRef50_Q62HD1 Cluster: Ferrochelatase; n=82; cellular organism... 101 3e-20
UniRef50_Q8IFR0 Cluster: Ferrochelatase; n=10; Plasmodium|Rep: F... 101 3e-20
UniRef50_A3QC13 Cluster: Ferrochelatase; n=5; Gammaproteobacteri... 100 4e-20
UniRef50_Q8DFM2 Cluster: Ferrochelatase; n=16; Gammaproteobacter... 98 3e-19
UniRef50_Q6F7N0 Cluster: Ferrochelatase; n=5; Moraxellaceae|Rep:... 97 4e-19
UniRef50_A3TKF4 Cluster: Putative ferrochelatase; n=3; Bacteria|... 94 4e-18
UniRef50_A3U6F4 Cluster: Ferrochelatase; n=14; Bacteroidetes|Rep... 94 5e-18
UniRef50_Q82KJ6 Cluster: Ferrochelatase; n=10; Actinobacteria (c... 93 1e-17
UniRef50_Q1ITV1 Cluster: Ferrochelatase; n=2; Acidobacteria|Rep:... 92 2e-17
UniRef50_Q5P1H1 Cluster: Ferrochelatase; n=3; Betaproteobacteria... 92 2e-17
UniRef50_Q1ZEV1 Cluster: Ferrochelatase; n=1; Psychromonas sp. C... 92 2e-17
UniRef50_Q3AEU4 Cluster: Ferrochelatase; n=1; Carboxydothermus h... 91 3e-17
UniRef50_Q98H61 Cluster: Ferrochelatase; n=31; Alphaproteobacter... 91 4e-17
UniRef50_Q9Z7V1 Cluster: Ferrochelatase; n=12; Chlamydiaceae|Rep... 91 4e-17
UniRef50_A1K8P4 Cluster: Ferrochelatase; n=3; Betaproteobacteria... 91 5e-17
UniRef50_Q72L32 Cluster: Ferrochelatase; n=2; Thermus thermophil... 90 6e-17
UniRef50_Q28VQ2 Cluster: Ferrochelatase; n=9; Rhodobacteraceae|R... 90 8e-17
UniRef50_Q9PFU1 Cluster: Ferrochelatase; n=13; Xanthomonadaceae|... 89 1e-16
UniRef50_Q9K097 Cluster: Ferrochelatase; n=5; Neisseria|Rep: Fer... 89 1e-16
UniRef50_Q97R30 Cluster: Ferrochelatase; n=18; Streptococcus|Rep... 89 2e-16
UniRef50_Q5DEU6 Cluster: SJCHGC05531 protein; n=1; Schistosoma j... 88 3e-16
UniRef50_Q8XW32 Cluster: Ferrochelatase; n=17; Proteobacteria|Re... 88 3e-16
UniRef50_Q82UK8 Cluster: Ferrochelatase; n=2; Betaproteobacteria... 87 6e-16
UniRef50_Q6MAW8 Cluster: Ferrochelatase; n=5; Bacteria|Rep: Ferr... 85 2e-15
UniRef50_Q6MHT3 Cluster: Ferrochelatase; n=1; Bdellovibrio bacte... 85 2e-15
UniRef50_Q8D226 Cluster: Ferrochelatase; n=1; Wigglesworthia glo... 85 3e-15
UniRef50_Q9CFB4 Cluster: Ferrochelatase; n=3; Lactococcus lactis... 84 4e-15
UniRef50_P28602 Cluster: Ferrochelatase; n=19; Proteobacteria|Re... 83 7e-15
UniRef50_A7BBG3 Cluster: Putative uncharacterized protein; n=1; ... 80 7e-14
UniRef50_A0L8B7 Cluster: Ferrochelatase; n=1; Magnetococcus sp. ... 80 7e-14
UniRef50_P57779 Cluster: Ferrochelatase; n=9; Bacteria|Rep: Ferr... 80 9e-14
UniRef50_Q88XC3 Cluster: Ferrochelatase; n=3; Lactobacillus|Rep:... 76 1e-12
UniRef50_P72183 Cluster: Ferrochelatase; n=1; Propionibacterium ... 75 3e-12
UniRef50_A6DTB4 Cluster: Ferrochelatase; n=1; Lentisphaera arane... 71 5e-11
UniRef50_Q5ZYE7 Cluster: Ferrochelatase; n=5; Legionella pneumop... 70 1e-10
UniRef50_O07401 Cluster: Ferrochelatase; n=1; Mycobacterium aviu... 68 4e-10
UniRef50_Q9HVD7 Cluster: Ferrochelatase; n=19; Pseudomonadaceae|... 67 5e-10
UniRef50_Q7MXP4 Cluster: Ferrochelatase; n=1; Porphyromonas ging... 66 1e-09
UniRef50_Q1DC34 Cluster: Ferrochelatase; n=3; Myxococcales|Rep: ... 65 3e-09
UniRef50_Q6AB01 Cluster: Ferrochelatase, HemH; n=1; Propionibact... 64 6e-09
UniRef50_Q83FA4 Cluster: Ferrochelatase; n=4; Coxiella burnetii|... 60 8e-08
UniRef50_A5V0K6 Cluster: Ferrochelatase; n=2; Roseiflexus|Rep: F... 56 1e-06
UniRef50_Q9HLB8 Cluster: Ferrochelatase; n=2; Thermoplasma|Rep: ... 56 1e-06
UniRef50_Q9BHB8 Cluster: Putative uncharacterized protein; n=2; ... 56 2e-06
UniRef50_Q4JSM9 Cluster: Ferrochelatase; n=1; Corynebacterium je... 51 5e-05
UniRef50_Q6L0G9 Cluster: Ferrochelatase; n=2; Thermoplasmatales|... 50 6e-05
UniRef50_A7CZ83 Cluster: Ferrochelatase; n=1; Opitutaceae bacter... 45 0.003
UniRef50_Q8YNF0 Cluster: Alr4616 protein; n=9; Cyanobacteria|Rep... 44 0.004
UniRef50_Q4QE43 Cluster: Ferrochelatase-like protein; n=21; Leis... 42 0.029
UniRef50_A7BEQ8 Cluster: Putative uncharacterized protein; n=1; ... 36 1.1
UniRef50_A6T0P6 Cluster: Patatin-like phospholipase; n=1; Janthi... 36 1.9
UniRef50_A6PNJ6 Cluster: UvrD/REP helicase; n=1; Victivallis vad... 36 1.9
UniRef50_Q9FUU1 Cluster: Ribosomal protein S10; n=1; Daucus caro... 36 1.9
UniRef50_Q9SS89 Cluster: F4P13.20 protein; n=5; Magnoliophyta|Re... 35 2.5
UniRef50_Q91L90 Cluster: ORF162; n=2; Shrimp white spot syndrome... 35 3.3
UniRef50_Q8EY34 Cluster: Ferrochelatase; n=5; Leptospira|Rep: Fe... 35 3.3
UniRef50_A4M8C8 Cluster: TPR repeat-containing protein; n=1; Pet... 35 3.3
UniRef50_A5UYH0 Cluster: Putative uncharacterized protein precur... 34 5.8
UniRef50_A4WPN2 Cluster: Putative uncharacterized protein precur... 34 5.8
UniRef50_Q82BJ3 Cluster: Putative ATP/GTP-binding protein; n=1; ... 33 7.7
UniRef50_Q47PK5 Cluster: CRISPR-associated protein, TM1811 C-ter... 33 7.7
UniRef50_A7RNJ9 Cluster: Predicted protein; n=1; Nematostella ve... 33 7.7
>UniRef50_Q967G9 Cluster: Ferrochelatase precursor; n=2;
Endopterygota|Rep: Ferrochelatase precursor - Chironomus
sp. YKL-2001
Length = 393
Score = 439 bits (1081), Expect = e-122
Identities = 198/304 (65%), Positives = 244/304 (80%)
Query: 18 VKPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVKKKYS 77
++PKTAI+MLNMGGP+T DQVGDYLHRIMTDR+M+QLP Q LGP+IA +RT +V+KKY
Sbjct: 35 LRPKTAILMLNMGGPQTKDQVGDYLHRIMTDREMMQLPFQDTLGPYIARKRTADVQKKYE 94
Query: 78 EIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADR 137
EIGGGSPILKWT QGSLL LDQ+ PE+APHK YV FRYV PFTED +E+ESD +R
Sbjct: 95 EIGGGSPILKWTQLQGSLLCNKLDQVSPETAPHKSYVGFRYVTPFTEDTIKEIESDRVER 154
Query: 138 VIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEK 197
V+IFSQYPQYSCAT+GSS N+I + + +N+K+S+I+RW +H LL K F+ERIKEK
Sbjct: 155 VVIFSQYPQYSCATSGSSFNSIFTHFGGKKPNSNIKWSMIDRWPTHHLLVKTFAERIKEK 214
Query: 198 LDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQSK 257
L +F RDD ++LF+AHSLPLK V RGD YP EV +TV+ M EL NP+ LVWQSK
Sbjct: 215 LAEFSPDKRDDAILLFSAHSLPLKNVRRGDAYPSEVGATVNAVMAELNYCNPYCLVWQSK 274
Query: 258 VGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVAKELRTIS 317
VGPLPWL+P+TDDAIK+YA +G K+ +L+P+AFVNEHIETLHELDIEYC ++AKE++
Sbjct: 275 VGPLPWLEPFTDDAIKMYAAKGKKNFVLIPIAFVNEHIETLHELDIEYCHDLAKEVKVEK 334
Query: 318 ELSA 321
L A
Sbjct: 335 ILRA 338
>UniRef50_P22830 Cluster: Ferrochelatase, mitochondrial precursor;
n=56; Fungi/Metazoa group|Rep: Ferrochelatase,
mitochondrial precursor - Homo sapiens (Human)
Length = 423
Score = 359 bits (883), Expect = 6e-98
Identities = 161/294 (54%), Positives = 220/294 (74%)
Query: 19 KPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVKKKYSE 78
KPKT I+MLNMGGPET V D+L R+ DRD++ LP+Q+KL P+IA RRT +++++Y
Sbjct: 66 KPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRR 125
Query: 79 IGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRV 138
IGGGSPI WT+ QG + + LD++ P +APHK+Y+ FRYV P TE+A E+E DG +R
Sbjct: 126 IGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERA 185
Query: 139 IIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKL 198
I F+QYPQYSC+TTGSSLNAI +Y +K+S I+RW +H LL + F++ I ++L
Sbjct: 186 IAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKEL 245
Query: 199 DKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQSKV 258
D F + R +V+ILF+AHSLP+ V+RGD YP EV++TV + ME L NP+RLVWQSKV
Sbjct: 246 DHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKV 305
Query: 259 GPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVAKE 312
GP+PWL P TD++IK ++G K+++LVP+AF ++HIETL+ELDIEY +AKE
Sbjct: 306 GPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKE 359
>UniRef50_Q4SRE0 Cluster: Ferrochelatase; n=1; Tetraodon
nigroviridis|Rep: Ferrochelatase - Tetraodon
nigroviridis (Green puffer)
Length = 409
Score = 310 bits (761), Expect = 3e-83
Identities = 139/244 (56%), Positives = 185/244 (75%)
Query: 19 KPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVKKKYSE 78
KPKT I+MLNMGGPE + V D+L R+ D D++QLPVQ+KLGP+IA RRT +++++YS+
Sbjct: 2 KPKTGILMLNMGGPEKLEDVHDFLLRLFMDTDLMQLPVQNKLGPFIAKRRTPKIQEQYSK 61
Query: 79 IGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRV 138
IGGGSPI +WT+ QG + + LD+M P++APHK Y+ FRYV P TE+A E+E DG +R
Sbjct: 62 IGGGSPIRRWTSMQGEGMVKLLDEMSPQTAPHKFYIGFRYVHPLTENAIEEMERDGVERA 121
Query: 139 IIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKL 198
+ F+QYPQYSC+TTGSSLNAI +Y NR + +S+I+RW +H LL + F+E I+ +L
Sbjct: 122 VAFTQYPQYSCSTTGSSLNAIYRYYSNRGERPKMSWSVIDRWPTHPLLVECFAEHIQNEL 181
Query: 199 DKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQSKV 258
+F E+ RDDV+ILF+AHSLP+ V+RGD YP EV +TV R ME LG NP+RLVWQSK
Sbjct: 182 LQFPEEKRDDVVILFSAHSLPMAVVNRGDPYPQEVGATVQRVMERLGHCNPYRLVWQSKQ 241
Query: 259 GPLP 262
P P
Sbjct: 242 PPSP 245
>UniRef50_Q5AVC8 Cluster: Ferrochelatase; n=9; Fungi/Metazoa
group|Rep: Ferrochelatase - Emericella nidulans
(Aspergillus nidulans)
Length = 419
Score = 298 bits (731), Expect = 1e-79
Identities = 149/318 (46%), Positives = 214/318 (67%), Gaps = 17/318 (5%)
Query: 6 LPPAFSTASGTAVKPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLP-VQSKLGPWI 64
+PP A+G+ K TA+V LNMGGP TT +V D+L R+ D D+I L +Q+ LGP I
Sbjct: 35 VPPVTQDATGS--KGPTAMVFLNMGGPSTTAEVEDFLSRLFADGDLIPLGRLQNYLGPLI 92
Query: 65 ASRRTEEVKKKYSEIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTE 124
A RRT +++++Y++IGGGSPI KW+ Q + + + LDQ+ PESAPHK YVAFRY P TE
Sbjct: 93 AKRRTPKIQRQYADIGGGSPIRKWSEYQCAEMCKLLDQLSPESAPHKPYVAFRYAAPLTE 152
Query: 125 DAFREVESDG-----ADRVIIFSQYPQYSCATTGSSLNAIADFY-RNRTTPAN------- 171
+ + ++ +DG R + F+QYPQYSC+TTGSSLN + + R AN
Sbjct: 153 EMYAQLLADGFGNGKGGRAVAFTQYPQYSCSTTGSSLNELWKWRTRLEGKRANCDVDATG 212
Query: 172 -VKFSLIERWASHKLLAKVFSERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYP 230
+++S+I+RW +H L + F+ I+++L + E+ R+ V++LF+AHSLP+ V+RGD YP
Sbjct: 213 TIQWSVIDRWPTHPGLIEAFARNIEDQLKTYPEEKRNSVVLLFSAHSLPMSVVNRGDPYP 272
Query: 231 HEVASTVSRTMEELGGRNPHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAF 290
EVA+TV M+ L NP+RL WQS+VGP WL T D ++ Y K+G L+LVP+AF
Sbjct: 273 AEVAATVHAVMQRLNFSNPYRLCWQSQVGPSAWLGAQTSDTVQEYVKRGQTDLVLVPIAF 332
Query: 291 VNEHIETLHELDIEYCDE 308
++HIETL+ELD+E +E
Sbjct: 333 TSDHIETLYELDLEVMEE 350
>UniRef50_A4RKF0 Cluster: Ferrochelatase; n=14; Pezizomycotina|Rep:
Ferrochelatase - Magnaporthe grisea (Rice blast fungus)
(Pyricularia grisea)
Length = 438
Score = 287 bits (704), Expect = 3e-76
Identities = 140/322 (43%), Positives = 209/322 (64%), Gaps = 25/322 (7%)
Query: 6 LPPAFSTASGTAVKPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQL-PVQSKLGPWI 64
+PP A+G+ K TA+V LNMGGP TT++V D+L R+ +D D+I P+Q L WI
Sbjct: 45 VPPVTQDATGS--KGPTAMVFLNMGGPSTTEEVHDFLLRLFSDADLIPFGPLQKYLAQWI 102
Query: 65 ASRRTEEVKKKYSEIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTE 124
+ RRT +++ +Y+ IGGGSPI KW+ Q + + + LD++ PE+APHK YVAFRY P TE
Sbjct: 103 SKRRTPKIQGQYAAIGGGSPIRKWSEHQNAEMCKLLDKISPETAPHKPYVAFRYANPLTE 162
Query: 125 DAFREVESDG-----ADRVIIFSQYPQYSCATTGSSLNAIADFYR--------------- 164
+ + + +DG R + F+QYPQYSC+TTGSSLN + + +
Sbjct: 163 EMYNRLLADGFGNGKGGRAVAFTQYPQYSCSTTGSSLNELWKWRQRLEGKSAEADGGSSA 222
Query: 165 --NRTTPANVKFSLIERWASHKLLAKVFSERIKEKLDKFDEKIRDDVLILFTAHSLPLKA 222
++ +++S+I+RW H L + F++ I+ KL ++ E+ R+ +++F+AHSLP+
Sbjct: 223 ALSKVNDGTIQWSVIDRWPVHAGLVEAFAQNIEAKLAEYPEERRNKAVLMFSAHSLPMTV 282
Query: 223 VSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKH 282
V+RGD YP EVA+TV M+ LG NP+RL WQS+VGP PWL P T +++ Y +G K
Sbjct: 283 VNRGDPYPAEVAATVYGVMQRLGFSNPYRLCWQSQVGPQPWLGPQTSTSVEEYVSKGQKD 342
Query: 283 LILVPVAFVNEHIETLHELDIE 304
++L+P+AF ++HIETL ELD E
Sbjct: 343 IVLIPIAFTSDHIETLFELDQE 364
>UniRef50_Q54IA8 Cluster: Ferrochelatase; n=1; Dictyostelium
discoideum AX4|Rep: Ferrochelatase - Dictyostelium
discoideum AX4
Length = 423
Score = 281 bits (689), Expect = 2e-74
Identities = 141/308 (45%), Positives = 194/308 (62%), Gaps = 23/308 (7%)
Query: 19 KPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVKKKYSE 78
K KT I+MLN+GGP ++V +L R+ TD+++ +LP Q G IA RR+ V K Y
Sbjct: 43 KIKTGILMLNLGGPSKLEEVEPFLTRLFTDKEIFKLPFQKYTGTLIAKRRSNAVMKLYEA 102
Query: 79 IGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRV 138
IGGGSPI KWT QG LL+ +D++ PE+APHKHY+ FRY P D ++E+D +RV
Sbjct: 103 IGGGSPIRKWTEKQGELLSSMMDKISPETAPHKHYIGFRYSDPLIADTLDQMENDNVERV 162
Query: 139 IIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKL 198
+ FSQYPQYSC TTGSSLN + + + K+S+I+RW HK +IK+
Sbjct: 163 VAFSQYPQYSCTTTGSSLNNLWKTLEEKQMQSKFKWSVIDRWQDHKGFIDATIHKIKKAY 222
Query: 199 DKFDEKIR----DDV-----------LILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEE 243
++F+ K+R DDV +++F+AHSLP+ V +GD YP EVA TV R M+
Sbjct: 223 NQFNSKLRELDIDDVDANNNNNNNKPVLVFSAHSLPMSTVEKGDPYPQEVAETVCRVMDG 282
Query: 244 LGGRN-------PHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIE 296
LG R+ + L WQSKVGPLPWL P T I+ AK+G ++ I++P+AF ++HIE
Sbjct: 283 LGIRDEETGKPLEYILAWQSKVGPLPWLSPKTSFVIEQLAKKG-RNAIVIPIAFTSDHIE 341
Query: 297 TLHELDIE 304
TL E+DIE
Sbjct: 342 TLSEIDIE 349
>UniRef50_P16622 Cluster: Ferrochelatase, mitochondrial precursor;
n=11; Ascomycota|Rep: Ferrochelatase, mitochondrial
precursor - Saccharomyces cerevisiae (Baker's yeast)
Length = 393
Score = 275 bits (674), Expect = 1e-72
Identities = 124/284 (43%), Positives = 192/284 (67%), Gaps = 3/284 (1%)
Query: 22 TAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPV--QSKLGPWIASRRTEEVKKKYSEI 79
T IV++NMGGP ++ D+L+++ D D+I + Q + +IA RT +++K+Y EI
Sbjct: 39 TGIVLMNMGGPSKVEETYDFLYQLFADNDLIPISAKYQKTIAKYIAKFRTPKIEKQYREI 98
Query: 80 GGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRVI 139
GGGSPI KW+ Q + + + LD+ PE+APHK YVAFRY P T + ++++ DG + +
Sbjct: 99 GGGSPIRKWSEYQATEVCKILDKTCPETAPHKPYVAFRYAKPLTAETYKQMLKDGVKKAV 158
Query: 140 IFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKLD 199
FSQYP +S +TTGSS+N + + + ++ +S+I+RW +++ L K FSE I +KL
Sbjct: 159 AFSQYPHFSYSTTGSSINELWRQIKALDSERSISWSVIDRWPTNEGLIKAFSENITKKLQ 218
Query: 200 KFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQSKVG 259
+F + +RD V++LF+AHSLP+ V+ GD YP EVA+TV M++L +NP+RLVWQS+VG
Sbjct: 219 EFPQPVRDKVVLLFSAHSLPMDVVNTGDAYPAEVAATVYNIMQKLKFKNPYRLVWQSQVG 278
Query: 260 PLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDI 303
P PWL T + + + V L+ +P+AF ++HIETLHE+D+
Sbjct: 279 PKPWLGAQTAEIAEFLGPK-VDGLMFIPIAFTSDHIETLHEIDL 321
>UniRef50_UPI0001509D16 Cluster: ferrochelatase family protein; n=1;
Tetrahymena thermophila SB210|Rep: ferrochelatase family
protein - Tetrahymena thermophila SB210
Length = 369
Score = 255 bits (624), Expect = 1e-66
Identities = 130/317 (41%), Positives = 194/317 (61%), Gaps = 6/317 (1%)
Query: 12 TASGTAVKPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRR-TE 70
T S + + KTA+ MLN+GGP + ++V +L R D +I++P LGP I R
Sbjct: 9 TFSSSKQQAKTAVFMLNLGGPNSLEEVSPFLERFFADSTVIRIPFG--LGPKIGKLRGPA 66
Query: 71 EVKKKYSEIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRY-VPPFTEDAFRE 129
+V K+Y IGG SPI WT QG + + LDQ+ P++APH ++ AFRY +P +TE
Sbjct: 67 KVTKQYEAIGGRSPIQDWTRKQGEKMVEKLDQISPDTAPHIYFPAFRYGLPLYTESIKEC 126
Query: 130 VESDGA-DRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAK 188
+E + ++ + FSQYPQYSC T G+++ + + +I+RW +H K
Sbjct: 127 IEKNPTVEKFVFFSQYPQYSCTTAGNNIREALKHLKEQYKNHGKTIHVIDRWYNHPGYVK 186
Query: 189 VFSERIKEKL-DKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGR 247
S + E L + F E+ RD+VLILF+AHSLP V +GDTYP+E+ +T + ++E +
Sbjct: 187 TISRLLSEDLKNNFKEEDRDNVLILFSAHSLPFDFVKQGDTYPYEIGTTANLVIQEAKLK 246
Query: 248 NPHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCD 307
NPHR+VWQSKVG WL P T A++ + QG K++ILVP+ F ++H+ETL+ELD+EY
Sbjct: 247 NPHRVVWQSKVGFQQWLAPNTMHALEQASNQGWKNVILVPLGFTSDHLETLYELDLEYIK 306
Query: 308 EVAKELRTISELSARFL 324
E ++L+ + AR L
Sbjct: 307 ESQEKLKFNKIIRARSL 323
>UniRef50_O04921 Cluster: Ferrochelatase-2, chloroplast precursor;
n=34; cellular organisms|Rep: Ferrochelatase-2,
chloroplast precursor - Arabidopsis thaliana (Mouse-ear
cress)
Length = 512
Score = 217 bits (529), Expect = 4e-55
Identities = 116/306 (37%), Positives = 181/306 (59%), Gaps = 14/306 (4%)
Query: 9 AFSTASGTAVKPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLP-----VQSKLGPW 63
A S++S K +++LN+GGPET D V +L + D D+I+LP +Q L +
Sbjct: 88 AISSSSVITDDAKIGVLLLNLGGPETLDDVQPFLFNLFADPDIIRLPPVFQFLQKPLAQF 147
Query: 64 IASRRTEEVKKKYSEIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFT 123
I+ R + K+ Y+ IGGGSP+ T++Q L + L + ++ P K YV RY PFT
Sbjct: 148 ISVARAPKSKEGYASIGGGSPLRHITDAQAEELRKCLWE---KNVPAKVYVGMRYWHPFT 204
Query: 124 EDAFREVESDGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASH 183
E+A +++ DG ++++ YPQ+S +T+GSSL + +R N++ ++I W
Sbjct: 205 EEAIEQIKRDGITKLVVLPLYPQFSISTSGSSLRLLERIFREDEYLVNMQHTVIPSWYQR 264
Query: 184 KLLAKVFSERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSR-GDTYPHEVASTVSRTME 242
+ K + I+ +L KF + V+I F+AH +PL V GD Y E+ V ME
Sbjct: 265 EGYIKAMANLIQSELGKFGSP--NQVVIFFSAHGVPLAYVEEAGDPYKAEMEECVDLIME 322
Query: 243 ELGGR---NPHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLH 299
EL R N + L +QS+VGP+ WL+PYT++AI K+GV++L+ VP++FV+EHIETL
Sbjct: 323 ELDKRKITNAYTLAYQSRVGPVEWLKPYTEEAITELGKKGVENLLAVPISFVSEHIETLE 382
Query: 300 ELDIEY 305
E+D+EY
Sbjct: 383 EIDVEY 388
>UniRef50_P42044 Cluster: Ferrochelatase-2, chloroplast precursor;
n=3; core eudicotyledons|Rep: Ferrochelatase-2,
chloroplast precursor - Cucumis sativus (Cucumber)
Length = 514
Score = 215 bits (526), Expect = 1e-54
Identities = 111/298 (37%), Positives = 177/298 (59%), Gaps = 14/298 (4%)
Query: 17 AVKPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLP-----VQSKLGPWIASRRTEE 71
AV K +++LN+GGPET D V +L+ + D D+I+LP +Q L I++ R +
Sbjct: 110 AVDDKVGVLLLNLGGPETLDDVQPFLYNLFADPDIIRLPRLFRFLQEPLAKLISTYRAPK 169
Query: 72 VKKKYSEIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVE 131
K+ Y+ IGGGSP+ K T+ Q L AL + ++ YV RY PFTE+A ++++
Sbjct: 170 SKEGYASIGGGSPLRKITDEQAQALKMALAE---KNMSTNVYVGMRYWYPFTEEAIQQIK 226
Query: 132 SDGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFS 191
DG R+++ YPQYS +TTGSS+ + +R +++ S+I+ W + K +
Sbjct: 227 RDGITRLVVLPLYPQYSISTTGSSIRVLQKMFREDAYLSSLPVSIIKSWYQREGYIKSMA 286
Query: 192 ERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSR-GDTYPHEVASTVSRTMEELGGR--- 247
+ ++ +L F +V+I F+AH +P+ V GD Y ++ + M+EL R
Sbjct: 287 DLMQAELKNFANP--QEVMIFFSAHGVPVSYVENAGDPYKDQMEECICLIMQELKARGIG 344
Query: 248 NPHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEY 305
N H L +QS+VGP+ WL+PYTD+ + ++G+K L+ VPV+FV+EHIETL E+D+EY
Sbjct: 345 NEHTLAYQSRVGPVQWLKPYTDEVLVELGQKGIKSLLAVPVSFVSEHIETLEEIDMEY 402
>UniRef50_Q747F5 Cluster: Ferrochelatase; n=7;
Desulfuromonadales|Rep: Ferrochelatase - Geobacter
sulfurreducens
Length = 317
Score = 211 bits (515), Expect = 2e-53
Identities = 118/296 (39%), Positives = 178/296 (60%), Gaps = 18/296 (6%)
Query: 21 KTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLP---VQSKLGPWIASRRTEEVKKKYS 77
KTA+++L MGGP++ D V +L + +DRD+I++ +Q + IA RR+ V++KY
Sbjct: 4 KTAVLLLQMGGPDSLDAVEPFLLNLFSDRDIIRIGPAFLQPFIARLIAKRRSPGVERKYE 63
Query: 78 EIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADR 137
EIGG SPI + T SQ +AL+ +L + ++ +VA RY P T +A + +G R
Sbjct: 64 EIGGKSPIRELTESQA----RALEDVLGDG--YRCFVAMRYWKPSTMEALAAIRREGISR 117
Query: 138 VIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSL--IERWASHKLLAKVFSERIK 195
VI S YP YS ATTGSS+N + + + + V+F + ++R+ H L +E+I+
Sbjct: 118 VIALSLYPHYSRATTGSSVNEL----KRVLSQSGVQFQMMYVDRFFDHPLYIDALAEKIR 173
Query: 196 EKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQ 255
E LD F +V +LF+AHSLP + GD Y + TV ME G H L +Q
Sbjct: 174 EGLDDFHPLA--EVQVLFSAHSLPQSFIDEGDPYLDHIRETVRLVMERFEGVT-HHLAFQ 230
Query: 256 SKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVAK 311
S+ GP+ WL+P TD+ ++ A VK+L++VP++FV++HIETLHE+DIEY E K
Sbjct: 231 SRAGPVKWLEPSTDEMLEHLAAHQVKNLLIVPLSFVSDHIETLHEIDIEYAQEAHK 286
>UniRef50_P42045 Cluster: Ferrochelatase-2, chloroplast precursor;
n=9; cellular organisms|Rep: Ferrochelatase-2,
chloroplast precursor - Hordeum vulgare (Barley)
Length = 484
Score = 209 bits (511), Expect = 7e-53
Identities = 113/301 (37%), Positives = 177/301 (58%), Gaps = 14/301 (4%)
Query: 14 SGTAVKPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLP-----VQSKLGPWIASRR 68
S AV+ K +++LN+GGPET + V +L + D D+I+LP +Q L I++ R
Sbjct: 101 SSHAVEEKVGVLLLNLGGPETLNDVQPFLFNLFADPDIIRLPRLFRFLQRPLAKLISTFR 160
Query: 69 TEEVKKKYSEIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFR 128
+ + Y+ IGGGSP+ K T+ Q + L AL E+ YV RY PFTE+A
Sbjct: 161 APKSNEGYASIGGGSPLRKITDEQANALKVALKSKNLEA---DIYVGMRYWYPFTEEAID 217
Query: 129 EVESDGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAK 188
+++ D ++++ YPQYS +T+GSS+ + + + A + S+IE W + K
Sbjct: 218 QIKKDKITKLVVLPLYPQYSISTSGSSIRVLQNIVKEDPYFAGLPISIIESWYQREGYVK 277
Query: 189 VFSERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVS-RGDTYPHEVASTVSRTMEELGGR 247
++ I+++L F ++V+I F+AH +PL V GD Y ++ ++ MEEL R
Sbjct: 278 SMADLIEKELSVFSNP--EEVMIFFSAHGVPLTYVKDAGDPYRDQMEDCIALIMEELKSR 335
Query: 248 ---NPHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIE 304
N H L +QS+VGP+ WL+PYTD+ + ++GVK L+ VPV+FV+EHIETL E+D+E
Sbjct: 336 GTLNDHTLAYQSRVGPVQWLKPYTDEVLVELGQKGVKSLLAVPVSFVSEHIETLEEIDME 395
Query: 305 Y 305
Y
Sbjct: 396 Y 396
>UniRef50_UPI0000E4A92D Cluster: PREDICTED: similar to
ferrochelatase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to ferrochelatase -
Strongylocentrotus purpuratus
Length = 261
Score = 204 bits (498), Expect = 2e-51
Identities = 101/182 (55%), Positives = 131/182 (71%), Gaps = 5/182 (2%)
Query: 13 ASG--TAVKPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTE 70
ASG T+ K KT I+MLNMGGPE TD+V D+L R+ D+D+I LP QSKL P IA RRT
Sbjct: 27 ASGQETSQKAKTGIMMLNMGGPENTDEVHDFLLRLFMDKDIIPLPAQSKLAPIIARRRTP 86
Query: 71 EVKKKYSEIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREV 130
+++ +Y +IGGGSPI KWT QG L + LD++ PE+APHK+Y+ FRYV P TED ++
Sbjct: 87 KIQAQYKKIGGGSPIKKWTKLQGEGLVKLLDKLSPETAPHKYYIGFRYVNPLTEDTIDQM 146
Query: 131 ESDGADRVIIFSQYPQYSCATTGSSLNAIADFY-RNRTTPAN--VKFSLIERWASHKLLA 187
E DG +R I F+QYPQYSC+TTGSSLNAI Y +N AN +K+S+I+RW + L
Sbjct: 147 ERDGIERAIAFTQYPQYSCSTTGSSLNAIYRHYAKNPEMVANSTMKWSVIDRWPVNAGLV 206
Query: 188 KV 189
+V
Sbjct: 207 EV 208
Score = 51.6 bits (118), Expect = 3e-05
Identities = 22/39 (56%), Positives = 29/39 (74%)
Query: 220 LKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQSKV 258
++ V+RGD YP EV +TV R ME L +P+RLVWQSK+
Sbjct: 206 VEVVNRGDPYPAEVGATVQRVMERLNFSHPYRLVWQSKM 244
>UniRef50_Q9ATG7 Cluster: Ferrochelatase; n=1; Polytomella sp.
Pringsheim 198.80|Rep: Ferrochelatase - Polytomella sp.
Pringsheim 198.80
Length = 440
Score = 200 bits (489), Expect = 3e-50
Identities = 113/302 (37%), Positives = 169/302 (55%), Gaps = 14/302 (4%)
Query: 13 ASGTAVKPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLP-VQSKLGPWIA----SR 67
+S ++ K + +LNMGGP T V +L+ + D D+I++P V + P +A S
Sbjct: 54 SSPSSPNEKLGVFLLNMGGPSTVKDVEPFLYNLFNDPDIIRMPPVANMFQPIVAKIISST 113
Query: 68 RTEEVKKKYSEIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAF 127
R + K Y IGGGSP+ T QG L +L++ K Y+ RY PFTED+
Sbjct: 114 RASKSAKGYESIGGGSPLYPLTKDQGDALQNSLEK---RGISAKMYIGMRYWHPFTEDSI 170
Query: 128 REVESDGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLA 187
+++++DG +++ YPQYS +TTGSSL I D + + + V ++I R++S
Sbjct: 171 KQIKADGITKLVALPLYPQYSISTTGSSLRCIRDEFNSDPYLSQVPLAVISRFSSRPGYI 230
Query: 188 KVFSERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRG-DTYPHEVASTVSRTMEELGG 246
+ ++ ++ +L KF +V I FTAH +P K V+ D Y E+ VS M +L
Sbjct: 231 QSMADLVQLELKKFQNP--SEVHIFFTAHGVPKKYVTDFLDPYQQEMEECVSLIMADLKA 288
Query: 247 R---NPHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDI 303
R N H L +QS+VGP WL+PYT +AI G K L+ VP++FV+EHIETL E+D
Sbjct: 289 RGVSNSHLLAYQSRVGPTEWLKPYTSEAIPALGALGCKGLLAVPISFVSEHIETLDEIDE 348
Query: 304 EY 305
EY
Sbjct: 349 EY 350
>UniRef50_UPI00015BC7F1 Cluster: UPI00015BC7F1 related cluster; n=1;
unknown|Rep: UPI00015BC7F1 UniRef100 entry - unknown
Length = 312
Score = 184 bits (449), Expect = 2e-45
Identities = 108/297 (36%), Positives = 169/297 (56%), Gaps = 22/297 (7%)
Query: 21 KTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLP--VQSKLGPWIASRRTEEVKKKYSE 78
KTA+V+LNMGGP++ + +L+ + +D D++Q+P +Q + I++ R ++ + Y
Sbjct: 3 KTAVVLLNMGGPDSMSAIRPFLYNLFSDHDIVQIPRSIQKPVAFLISTFRAKKTEYYYKI 62
Query: 79 IGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRV 138
+GG SP + T Q + L QAL Q + +A RY PFT +A +E ++
Sbjct: 63 MGGKSPQKEQTILQKNALQQALGQ------DYIVEIAMRYWHPFTAEAISNLEKVKPSKI 116
Query: 139 IIFSQYPQYSCATTGSSLNAIADFYR--NRTTPANVKFSLIERWASHKLLAKVFSERIKE 196
++ YP YS TTGSS +FYR +++ + I + H L K ++E IK
Sbjct: 117 VLLPLYPHYSSTTTGSSFK---EFYRLFKKSSLKDTPVKEIRDYHDHPLFIKAWTENIK- 172
Query: 197 KLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQS 256
+ I D+ ILF+AHSLP K + + D Y ++ +V M+ +N + + +QS
Sbjct: 173 -----NSGIDDEYFILFSAHSLPQKIIDKKDPYKDQIEKSVELIMKNF--KNKYMISYQS 225
Query: 257 KVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVAKEL 313
KVGP+ WL+P TD I+ AKQG+K L LVP++FV+EH ETL+E+D Y +AKEL
Sbjct: 226 KVGPVKWLEPPTDKTIENLAKQGIKKLCLVPISFVSEHSETLYEMDYLY-KNMAKEL 281
>UniRef50_Q1K4G8 Cluster: Ferrochelatase; n=1; Desulfuromonas
acetoxidans DSM 684|Rep: Ferrochelatase - Desulfuromonas
acetoxidans DSM 684
Length = 322
Score = 184 bits (448), Expect = 3e-45
Identities = 103/294 (35%), Positives = 166/294 (56%), Gaps = 16/294 (5%)
Query: 19 KPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLP----VQSKLGPWIASRRTEEVKK 74
+PK A+V+LNMGGP++ + V +L+++ +DRD+IQLP +Q I+ R + V++
Sbjct: 3 EPKKALVLLNMGGPDSVEAVEPFLYQLFSDRDLIQLPLGALLQKPFAKMISHFRAKTVRE 62
Query: 75 KYSEIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDG 134
Y IGG SP+L W+ Q L + + +VA RY P ++ + + + G
Sbjct: 63 NYRRIGGKSPLLHWSRLQAEKTCDKLGE------DWQAFVAMRYWGPRADEVVQRIVAQG 116
Query: 135 ADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPA-NVKFSLIERWASHKLLAKVFSER 193
++ S YP Y+ ATTGSS I DF R + A +++ IE W +E
Sbjct: 117 IKEAVVVSLYPHYTGATTGSS---IKDFKRAVSQHAPDLQCRYIEEWHDQDQYLDALAEC 173
Query: 194 IKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLV 253
+++ L + E R + +LF+AH+LP K + RGD Y V TV+ ME +G P ++
Sbjct: 174 VQDGLAQVPEAKRGKLTLLFSAHALPQKFIDRGDPYQQHVEETVAGVMERVGD-YPCQIG 232
Query: 254 WQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCD 307
+QS+ GP+ W+ P T D I K+ + L+++PV+FV++HIETL E+D+E+ D
Sbjct: 233 YQSRSGPVKWMSPDTLDLIAAAGKER-RSLLVIPVSFVSDHIETLEEVDVEFRD 285
>UniRef50_O67083 Cluster: Ferrochelatase; n=1; Aquifex aeolicus|Rep:
Ferrochelatase - Aquifex aeolicus
Length = 309
Score = 184 bits (448), Expect = 3e-45
Identities = 108/295 (36%), Positives = 168/295 (56%), Gaps = 18/295 (6%)
Query: 21 KTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVKKKYSEIG 80
K ++++N+GGP++ + V +L+ + +D D+ LP Q L IA R ++ + Y +G
Sbjct: 2 KKGVILINLGGPDSLEAVEPFLYNLFSDPDIFSLPFQKVLAKIIAKLRAKKTRHYYELMG 61
Query: 81 GGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRVII 140
G SP + T Q +AL + L E +K V RY P+ +DA E+ +G + VI+
Sbjct: 62 GKSPQYEQTLEQA----KALQERLGED--YKVVVGMRYWKPYIKDALSELLKEGINEVIL 115
Query: 141 FSQYPQYSCATTGSSLNAIADFYRNRTT--PANVKFSLIERWASHKLLAKVFSERIKEKL 198
YPQYS TTGS+ N +F R++ ++K IE + H L K ++E+IK+ +
Sbjct: 116 LPLYPQYSKTTTGSAFN---EFERSKKALKADHIKVKKIEHFYDHPLYIKAWAEQIKQSV 172
Query: 199 DKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQSKV 258
+K +E LF+AHSLP K + GD Y + TV ME + L +QSKV
Sbjct: 173 EKPEE-----YHFLFSAHSLPKKLIEEGDPYQEQTEKTVKLIMENFP-EVEYTLAYQSKV 226
Query: 259 GPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVAKEL 313
G WL+P TD+ I+ K+ VK L+++P++FV+EH ETL+ELD +Y E+A+EL
Sbjct: 227 GFGKWLEPSTDEVIRNLIKKEVKKLLVIPISFVSEHSETLYELDKQY-RELAQEL 280
>UniRef50_Q2RZ44 Cluster: Ferrochelatase; n=1; Salinibacter ruber
DSM 13855|Rep: Ferrochelatase - Salinibacter ruber
(strain DSM 13855)
Length = 394
Score = 184 bits (447), Expect = 4e-45
Identities = 115/310 (37%), Positives = 172/310 (55%), Gaps = 17/310 (5%)
Query: 24 IVMLNMGGPETTDQVGDYLHRIMTDRDMIQLP----------VQSKLGPWIASRRTEEVK 73
+V+LN+GGP+ + V +L+ + D +I V+ I+ R++ V
Sbjct: 9 VVLLNLGGPDGEESVEPFLYNLFMDPAIIDFSEVVYFQARGRVRQAFSKIISYFRSQSVA 68
Query: 74 KKYSEIG--GGSPILKWTNSQGSLLTQAL-DQMLPES-APHKHYVAFRYVPPFTEDAFRE 129
+ Y EI GGSPI T Q L Q L +Q E+ A K Y+A RY PF+EDA +
Sbjct: 69 EDYKEISDDGGSPINPLTRDQADNLEQTLNEQYAAETGATFKTYMAMRYWEPFSEDAAAQ 128
Query: 130 VESDGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKV 189
++ DG D+V++ YPQYS TTG+SL + + PA S+ E +A++ +
Sbjct: 129 MQEDGVDKVVLLPLYPQYSKTTTGASLVYWHELEKAGEIPAWPTTSVFE-YATYPKYIEA 187
Query: 190 FSERIKEKLDKFDEKIRDDVLILFTAHSLPLKAV-SRGDTYPHEVASTVSRTMEELGGRN 248
S+RI E L++F + +RDDV +LF+AH PL + R D Y V STV ME G +
Sbjct: 188 LSDRIDEGLERFPDDVRDDVHLLFSAHGTPLSEMKDRDDPYCCLVHSTVKHLMEHRGFDH 247
Query: 249 PHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDE 308
+QSKVGP WL P TDD ++ A++G + ++++PVAFV +HIET +EL IE ++
Sbjct: 248 DFSTAFQSKVGPSEWLTPATDDTVEELAEEG-EDVLVIPVAFVTDHIETSYELAIEIPED 306
Query: 309 VAKELRTISE 318
+ +E I E
Sbjct: 307 LEEEGAPIPE 316
>UniRef50_Q3A6H8 Cluster: Ferrochelatase; n=1; Pelobacter
carbinolicus DSM 2380|Rep: Ferrochelatase - Pelobacter
carbinolicus (strain DSM 2380 / Gra Bd 1)
Length = 352
Score = 183 bits (446), Expect = 5e-45
Identities = 105/310 (33%), Positives = 170/310 (54%), Gaps = 17/310 (5%)
Query: 21 KTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLP----VQSKLGPWIASRRTEEVKKKY 76
KTA++ LNMGGP+ + V +L + +DR++I+LP +Q +A R + ++ Y
Sbjct: 15 KTALISLNMGGPDRPESVAPFLRNLFSDRELIRLPGGAWLQRPFARLMARLRAPKARRAY 74
Query: 77 SEIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGAD 136
IGG SP+ WT Q T+A+ ++L E + V RY P ++ + +G
Sbjct: 75 EAIGGASPLRIWTECQ----TRAIGRLLGEE--WRTAVIMRYWEPRAKEVLTHLRREGVK 128
Query: 137 RVIIFSQYPQYSCATTGSSLNAIADFYRN--RTTPANVKFSLIERWASHKLLAKVFSERI 194
R ++ S YP ++ AT+GSS+N DF R+ R P + + LI W + +
Sbjct: 129 RAMVLSLYPHFTAATSGSSIN---DFCRHAVRFCP-ELDYRLIHDWFDWPPFLDALAHLV 184
Query: 195 KEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGG-RNPHRLV 253
+E L +FD + R V +LF+AH+LP K + GD Y +V +T+ +E L R+ RL
Sbjct: 185 REALARFDGEQRHRVTLLFSAHALPEKLILEGDPYLDQVRTTMRGVLERLPEYRSRSRLA 244
Query: 254 WQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVAKEL 313
+QS+ GP+ W+ P +A+ +GV+ +++VPV+FV++H+ETLHE+D Y D +
Sbjct: 245 FQSRSGPVRWIGPSVTEALDTLVDEGVREVLVVPVSFVSDHVETLHEIDQGYRDYALRRG 304
Query: 314 RTISELSARF 323
T E A F
Sbjct: 305 MTRFERVAAF 314
>UniRef50_A3EV75 Cluster: Protoheme ferro-lyase; n=1; Leptospirillum
sp. Group II UBA|Rep: Protoheme ferro-lyase -
Leptospirillum sp. Group II UBA
Length = 356
Score = 180 bits (437), Expect = 6e-44
Identities = 113/298 (37%), Positives = 168/298 (56%), Gaps = 19/298 (6%)
Query: 20 PKTA--IVMLNMGGPETTDQVGDYLHRIMTDRDMIQLP--VQSKLGPWIASRRTEEVKKK 75
PKT +++ N+GGPET + V +L + +D D+ ++P +Q L IA RR + ++
Sbjct: 9 PKTTRGVLLFNLGGPETLEDVYPFLLNLFSDPDIFRVPRLIQPLLARIIARRRAPKSREY 68
Query: 76 YSEIGGGSPILKWTNSQGSLLTQALDQMLPESAPH-KHYVAFRYVPPFTEDAFREVESDG 134
Y +IGGGSP+ K T+ Q LL + L++ E+ H K V RY PP T DA RE+ G
Sbjct: 69 YRQIGGGSPLRKITDDQARLLEETLNR--EETNVHWKVRVGMRYAPPRTADALRELVDSG 126
Query: 135 ADRVIIFSQYPQYSCATTGSSL-NAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSER 193
+ ++ YPQ S TTGSS A+A+ R P + I W + K +E
Sbjct: 127 VNDLVFLPLYPQRSRTTTGSSFREALAE--AKRIAP-GLPVRTIPAWPVYPPYIKSLAET 183
Query: 194 IKEKLDKFDEKIRDDVLILFTAHSLPLKAVSR-GDTYPHEVASTVSRTMEELGGRNP--- 249
+ + L + E+ + V ILF+AH +P V+R D Y + +TVS ME L +P
Sbjct: 184 VGDALSRIPEE--ETVHILFSAHGIPEFLVTREKDPYEADTNATVSAAMEALQKFHPQRK 241
Query: 250 --HRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEY 305
H L +QS+VGPL WL P T + A +GV+HL++VP++FV++H ETL+E+DI Y
Sbjct: 242 LLHHLSYQSRVGPLKWLGPETRLELSRLAGEGVRHLVMVPISFVSDHQETLYEMDILY 299
>UniRef50_Q6BFD7 Cluster: Ferrochelatase (EC 4.99.1.1), putative;
n=1; Paramecium tetraurelia|Rep: Ferrochelatase (EC
4.99.1.1), putative - Paramecium tetraurelia
Length = 381
Score = 178 bits (433), Expect = 2e-43
Identities = 107/306 (34%), Positives = 173/306 (56%), Gaps = 20/306 (6%)
Query: 19 KPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRR-TEEVKKKYS 77
K +TAI+MLN+GGP + ++ +L R D +I++P LGP+IA R ++ K+Y
Sbjct: 30 KNQTAILMLNLGGPNSYQEISPFLVRFFEDTTVIRIPFG--LGPYIARLRGPAKINKQYE 87
Query: 78 EIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREV--ESDGA 135
+IGG SP+ KWT QG L+++ P+ + AFRY P EDA +++G
Sbjct: 88 KIGGFSPLFKWTMVQGILMSK------PQGSGF--LPAFRYGLPLQEDAIEYAFEKTEGR 139
Query: 136 -DRVIIFSQYPQYSCATTGSSL-NAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSER 193
+ ++FSQYPQYSC+T G+++ NAI + +T ++ S+I+ W +K +
Sbjct: 140 IQKFLLFSQYPQYSCSTGGNAIRNAIELLQKYKTIQPKLEVSVIDSWHKNKFYISAMATL 199
Query: 194 IKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPH---EVASTVSRTMEELGGRNPH 250
+ K+ K D LILFTAHSLP V G+ YP+ E V ++ +G
Sbjct: 200 LNNKI-KAQNLDPKDTLILFTAHSLPADFVWDGEKYPYYIYESCQLVIDNLKNMGVSITF 258
Query: 251 RLVWQSKVGPLPWLQPYTDDAIKLYAKQG-VKHLILVPVAFVNEHIETLHELDIEYCDEV 309
L +QSKVG WL+P T A+ Y + K++++ P+ F ++H+ETL+ELDI+ +++
Sbjct: 259 DLSYQSKVGLNKWLRPATHHALSQYIRNSKFKNILISPMGFTSDHLETLYELDIQLMEDL 318
Query: 310 AKELRT 315
K++ +
Sbjct: 319 KKDIES 324
>UniRef50_Q7VD58 Cluster: Ferrochelatase; n=20; Cyanobacteria|Rep:
Ferrochelatase - Prochlorococcus marinus
Length = 391
Score = 176 bits (429), Expect = 6e-43
Identities = 97/293 (33%), Positives = 157/293 (53%), Gaps = 13/293 (4%)
Query: 21 KTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPV---QSKLGPWIASRRTEEVKKKYS 77
+ ++++N+GGPE VG +L+ + +D ++I+LP+ Q L +I++ R+ + +K Y
Sbjct: 3 RVGVLLMNLGGPERIKDVGPFLYNLFSDPEIIRLPLPIFQKPLAWFISTLRSSKSQKAYQ 62
Query: 78 EIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADR 137
IGGGSP+ + T Q L AL YVA RY PFTE A ++++D +
Sbjct: 63 AIGGGSPLRRITEQQARELQSALRN---RGINATSYVAMRYWHPFTESAVEDIKADNINE 119
Query: 138 VIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEK 197
V++ YP +S +T+GSS + + I W + +E I+++
Sbjct: 120 VVVLPLYPHFSISTSGSSFRELRRLREVDKEFQKLSIRCIRSWFDNTGYIASMAELIEQE 179
Query: 198 LDKFDEKIRDDVLILFTAHSLPLKAVSR-GDTYPHEVAST----VSRTMEELGGRNPHRL 252
+ + + I FTAH +P V GD Y E+ + + + LG N + L
Sbjct: 180 ISSCESP--NAAHICFTAHGVPKSYVEEAGDPYKDEIQDCALLIIDKVEKSLGFSNSYTL 237
Query: 253 VWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEY 305
+QS+VGP WL+PYT++ ++ GVK LI+VP++FV+EHIETL E+DIEY
Sbjct: 238 SYQSRVGPEEWLKPYTEEVLEELGANGVKELIVVPISFVSEHIETLQEIDIEY 290
>UniRef50_Q6APB0 Cluster: Ferrochelatase; n=1; Desulfotalea
psychrophila|Rep: Ferrochelatase - Desulfotalea
psychrophila
Length = 320
Score = 176 bits (428), Expect = 7e-43
Identities = 100/293 (34%), Positives = 162/293 (55%), Gaps = 14/293 (4%)
Query: 22 TAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLP---VQSKLGPWIASRRTEEVKKKYSE 78
T +++LNMGGP T V +L+ + +DR++I L +Q L IA RR + Y
Sbjct: 6 TGVILLNMGGPTQTKDVRPFLYNLFSDREIIPLGPRLMQKPLAWLIAKRRAPKSAATYER 65
Query: 79 IGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRV 138
IGGGSP+ + T +Q +AL++ L A RY PP+ ++A + S G +R+
Sbjct: 66 IGGGSPLKQITEAQA----EALEKSLQAHGNFTVTYAMRYWPPYCDEALDYLLSKGVERL 121
Query: 139 IIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKL 198
+ S YP YS ATTGSSL + + + ++ + I W + + IK+ L
Sbjct: 122 VALSLYPHYSKATTGSSLTQLHKTLKKKNI--SLPLTEIPSWPKQRDYIAAIAANIKKGL 179
Query: 199 DKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQSKV 258
F + + I+++AHSLP + GD Y ++ +EE+ G+ RL +QSK
Sbjct: 180 ATFHGEKTE---IVYSAHSLPTSFIEAGDPYVEHTKQSIG-AIEEITGKRG-RLCFQSKS 234
Query: 259 GPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVAK 311
GP+ WL+P T D + A++GVK++++VP++FV++H+ETL+E+DI Y + K
Sbjct: 235 GPVEWLEPSTPDVLIQLAQEGVKNILMVPISFVSDHVETLYEIDILYKKQAKK 287
>UniRef50_Q2S1S2 Cluster: Ferrochelatase; n=1; Salinibacter ruber
DSM 13855|Rep: Ferrochelatase - Salinibacter ruber
(strain DSM 13855)
Length = 447
Score = 175 bits (426), Expect = 1e-42
Identities = 95/291 (32%), Positives = 156/291 (53%), Gaps = 8/291 (2%)
Query: 21 KTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASR----RTEEVKKKY 76
+ +V+ N+GGP T +V +L+R++ D ++ +PV ++ W+A R +++ Y
Sbjct: 34 RVGVVLFNLGGPSTLGEVEPFLYRLLMDPLLLDVPVGGRMRRWLARSVAYLRAGTLREHY 93
Query: 77 SEIGGGSPILKWTNSQGSLLTQALDQML--PESAPHKHYVAFRYVPPFTEDAFREVESDG 134
IGG SP+ + Q ++L LD P + Y A RY PF E ++E+DG
Sbjct: 94 ELIGGASPVPRLAREQATVLQDHLDARYGGPAGVGVRVYSAMRYGRPFPEKVAADMEADG 153
Query: 135 ADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERI 194
D+V++ YPQY+ TTGS+L A R + +++ +A++ + SERI
Sbjct: 154 VDKVVLVPSYPQYAAGTTGSAL-AYWKALGARGERPSWPTTVVPEYAANPKYVQAVSERI 212
Query: 195 KEKLDKFDEKIRDDVLILFTAHSLPLKAVS-RGDTYPHEVASTVSRTMEELGGRNPHRLV 253
E L +F +R++V ++F+AH A R Y V STV R M+ G P R
Sbjct: 213 DEALQRFPRHVREEVALVFSAHGSVFDAQGPRKPPYCCHVHSTVDRVMQHRGRDRPFRTA 272
Query: 254 WQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIE 304
+QS +GP WL P T D I A+QG + +++VP+AFV +H+ ++LD++
Sbjct: 273 FQSLMGPNHWLTPSTPDTIAALAEQGHRAVLVVPIAFVTDHVNVRYDLDVD 323
>UniRef50_Q1V1A3 Cluster: Ferrochelatase; n=2; Candidatus
Pelagibacter ubique|Rep: Ferrochelatase - Candidatus
Pelagibacter ubique HTCC1002
Length = 344
Score = 173 bits (420), Expect = 7e-42
Identities = 102/288 (35%), Positives = 161/288 (55%), Gaps = 12/288 (4%)
Query: 21 KTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLP--VQSKLGPWIASRRTEEVKKKYSE 78
K A+++ N+GGP+ + V +L + D ++ LP ++ L I++RR KK Y E
Sbjct: 2 KKAVILFNLGGPDKIENVEPFLFNLFNDPAILNLPTILRYPLAKLISNRRAPVAKKIYKE 61
Query: 79 IGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRV 138
+GG SPILK T Q L L+Q +S +K ++ R P D ++V+S + +
Sbjct: 62 LGGSSPILKLTMEQSKALETKLNQTEIDSE-YKCFIVMRCWNPRANDVIKDVQSFNPEEI 120
Query: 139 IIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKL 198
I+ YPQYS AT+GSS+ D + +VK + I + + + ++ I +K+
Sbjct: 121 ILMPLYPQYSAATSGSSIKEWRDVCKKNNY--HVKTNTICCYPTDQNFINAHTKEIIKKI 178
Query: 199 DKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLV-WQSK 257
K + ++F+AH LP K + +GD Y +V +V + +E L N ++ +QS+
Sbjct: 179 -----KDLKNFKLIFSAHGLPEKNIKKGDPYQWQVEQSVKKIVENLNIENLDWILSYQSR 233
Query: 258 VGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEY 305
VGPL W+ P T+D I +K G KH++LVP+AFV+EH ETL ELDIEY
Sbjct: 234 VGPLKWIGPSTEDIIIENSKLG-KHIVLVPIAFVSEHSETLVELDIEY 280
>UniRef50_Q4UJN9 Cluster: Ferrochelatase; n=16; Rickettsiales|Rep:
Ferrochelatase - Rickettsia felis (Rickettsia azadi)
Length = 344
Score = 171 bits (416), Expect = 2e-41
Identities = 102/291 (35%), Positives = 164/291 (56%), Gaps = 15/291 (5%)
Query: 18 VKPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSK--LGPWIASRRTEEVKKK 75
+K + AIV+ N+GGP+ + V +L + D+ +I LP + + I++ R + +K
Sbjct: 1 MKKRIAIVLFNLGGPKNLESVKPFLFNLFYDKAIINLPNPFRYIIAKIISTTRERKSQKI 60
Query: 76 YSEIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGA 135
YS IGG S +L+ T Q LT+ L Q++ E ++ RY PF ++ +++
Sbjct: 61 YSLIGGKSSLLQETEEQKLALTEKLKQLIKED--FAIFINMRYSAPFAKEVIDQIKKYNP 118
Query: 136 DRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIK 195
+I+ YPQ+S TTGSS + +F +N ++K I + + K IK
Sbjct: 119 SEIILLPLYPQFSSTTTGSS---VKNFLQNFDIDISIK--TICCYPQEEDFIKSHVSLIK 173
Query: 196 EKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRN-PHRLVW 254
EKL D+ R ILF+AH LP K + GD Y ++ TV ++EL ++ +++ +
Sbjct: 174 EKLYDDDKNFR----ILFSAHGLPEKIIKAGDPYSFQIKETVKAIVKELNIKDLDYKITY 229
Query: 255 QSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEY 305
QS+VGP+ WL+P T+D I+L K K +I+VP++FV+EH+ETL ELDIEY
Sbjct: 230 QSRVGPIEWLKPNTEDEIELAGKLK-KDIIIVPISFVSEHVETLVELDIEY 279
>UniRef50_P57777 Cluster: Ferrochelatase; n=12;
Alphaproteobacteria|Rep: Ferrochelatase - Caulobacter
crescentus (Caulobacter vibrioides)
Length = 347
Score = 166 bits (404), Expect = 6e-40
Identities = 100/295 (33%), Positives = 157/295 (53%), Gaps = 12/295 (4%)
Query: 21 KTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLP--VQSKLGPWIASRRTEEVKKKYSE 78
K A+V+ N+GGP+ D V +L + D +I P ++ L I++ R + K Y+
Sbjct: 4 KLAVVLFNLGGPDGPDAVRPFLFNLFRDPAIIGAPALIRYPLAALISTTREKSAKANYAI 63
Query: 79 IGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRV 138
+GGGSP+L T Q L AL +P K ++A RY P T++ R+V + D+V
Sbjct: 64 MGGGSPLLPETEKQARALEAALALAMP-GVEAKCFIAMRYWHPLTDETARQVAAFAPDQV 122
Query: 139 IIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKL 198
++ YPQ+S TTGSSL A Y+ V + + L + + I+E
Sbjct: 123 VLLPLYPQFSTTTTGSSLKAWKKTYKGSGVQTTVGC-----YPTEGGLIEAHARMIRESW 177
Query: 199 DKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQSKV 258
+K ++ +LF+AH LP K + GD Y +V +T + L + + +QS+V
Sbjct: 178 EKAGSPT--NIRLLFSAHGLPEKVILAGDPYQKQVEATAAAVAAHLPPQIEWTVCYQSRV 235
Query: 259 GPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVAKEL 313
GPL W+ P TDD I+ + K +++ P+AFV+EH+ETL ELD EY E+A+E+
Sbjct: 236 GPLKWIGPSTDDEIRRAGGED-KGVMITPIAFVSEHVETLVELDHEYA-ELAEEV 288
>UniRef50_P56107 Cluster: Ferrochelatase; n=5;
Helicobacteraceae|Rep: Ferrochelatase - Helicobacter
pylori (Campylobacter pylori)
Length = 334
Score = 156 bits (379), Expect = 6e-37
Identities = 96/294 (32%), Positives = 159/294 (54%), Gaps = 23/294 (7%)
Query: 20 PKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLP---VQSKLGPWIASRRTEEVKKKY 76
PK A+++LNMGGP + +VG +L + D ++ + ++ +G I + R E+ KK Y
Sbjct: 19 PKEAVILLNMGGPNSLYEVGVFLKNMFDDPFILTIKNNFMRKMVGKMIVNSRIEKSKKIY 78
Query: 77 SEIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYV-AFRYVPPFTEDAFREVESDGA 135
++GG SP+ +T AL + L + P + Y A RY PP+ +++
Sbjct: 79 EKLGGKSPLTP--------ITFALTERLNKLDPSRFYTYAMRYTPPYASMVLQDLALKEV 130
Query: 136 DRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIK 195
+ ++ FS YPQYS TT SS N + ++ T K +IER+ + K L K+ I
Sbjct: 131 ESLVFFSMYPQYSSTTTLSSFNDAFNALKSLET-FRPKVRVIERFYASKKLNKIILNTI- 188
Query: 196 EKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRN-PHR--- 251
L+ + + D +++F+ H LP + GDTY E VS E + +N P +
Sbjct: 189 --LNTLNNRKSQDFVLIFSVHGLPKSVIDAGDTYQQECEHHVSLLKELMQQKNTPFKEVL 246
Query: 252 LVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEY 305
L +QSK+GP+ WL+P T++ I+ + K H+I+ P+AF ++ ETL+ELD++Y
Sbjct: 247 LSYQSKLGPMKWLEPSTEELIEKHRK---SHIIIYPLAFTIDNSETLYELDMQY 297
>UniRef50_A7H9E2 Cluster: Ferrochelatase; n=2; Anaeromyxobacter|Rep:
Ferrochelatase - Anaeromyxobacter sp. Fw109-5
Length = 319
Score = 153 bits (371), Expect = 6e-36
Identities = 93/285 (32%), Positives = 151/285 (52%), Gaps = 17/285 (5%)
Query: 22 TAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPV---QSKLGPWIASRRTEEVKKKYSE 78
TA+ ++N+GGP + ++V YL+ + +D +I P + + I+ R +KY+
Sbjct: 4 TAVFLMNLGGPRSLEEVEPYLYELFSDPLLITAPFGPFRPLVARLISRLRAPSSAEKYAL 63
Query: 79 IGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRV 138
IGG SPI++ T +Q L +AL P + H +A R P TE+ RE + GA R
Sbjct: 64 IGGKSPIVEGTEAQARALQRALG---PGWSCH---LAMRCGHPSTEEGVREALAAGATRA 117
Query: 139 IIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKL 198
+ YPQY+ ATT SSL + R P + + I W H+ + ++E L
Sbjct: 118 VALPLYPQYANATTRSSLVEL-----RRVWPGELPLAEICTWHDHEGYLDASAAALRETL 172
Query: 199 DKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQSKV 258
+ R L++F+AH LP+ V +GD YP + + T G + R+ +QS+V
Sbjct: 173 EALPASDRASALVVFSAHGLPMSQVRKGDPYPGYIEHSARETARRAGAQE-FRVTYQSRV 231
Query: 259 GPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDI 303
GP WL P T + ++ A+ + ++ VP+AFV+EH+ETL++LD+
Sbjct: 232 GPAKWLGPDTVEFLEANARG--RAVVTVPIAFVSEHLETLYDLDV 274
>UniRef50_Q2RN84 Cluster: Ferrochelatase; n=2;
Alphaproteobacteria|Rep: Ferrochelatase - Rhodospirillum
rubrum (strain ATCC 11170 / NCIB 8255)
Length = 362
Score = 152 bits (368), Expect = 1e-35
Identities = 97/297 (32%), Positives = 159/297 (53%), Gaps = 12/297 (4%)
Query: 21 KTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSK--LGPWIASRRTEEVKKKYSE 78
+ A+V+ N+GGP++ + V +L + D +I+ P ++ L I+ RR ++ Y
Sbjct: 3 RIAVVLFNLGGPDSPEAVRPFLFNLFNDPAIIEGPSLTRWVLARLISWRRAPIAREIYGH 62
Query: 79 IGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRV 138
+GG SP+L+ T Q L +AL + ++ + +A RY P T +A + ++ D+V
Sbjct: 63 LGGRSPLLEQTEGQARALEKALSERGHDA---RCLIAMRYWKPLTREAVKAAKAWNPDQV 119
Query: 139 IIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKL 198
++ YPQ+S T+GSSLN + + +A+ L +ER L
Sbjct: 120 VLLPLYPQFSGTTSGSSLNQWT--VEAEKAGLTAQTHTVCCYATEVGLITALAERTLGGL 177
Query: 199 DKFDEKI--RDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRN-PHRLVWQ 255
++ E +LF+AH LP K V GD Y V +TV+ + + +++ +Q
Sbjct: 178 EQVRESTVGLPAPRVLFSAHGLPRKVVDAGDPYQSHVEATVNAVVAAMAVEGLDYQVCYQ 237
Query: 256 SKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVAKE 312
S+VGPL W+ P T+D I ++G + L++VPVAFV+EH ETL ELDIEY E+A+E
Sbjct: 238 SRVGPLEWIGPSTEDEIAKAGREG-RPLVVVPVAFVSEHSETLVELDIEY-GELAEE 292
>UniRef50_Q0BWA5 Cluster: Ferrochelatase; n=1; Hyphomonas neptunium
ATCC 15444|Rep: Ferrochelatase - Hyphomonas neptunium
(strain ATCC 15444)
Length = 357
Score = 150 bits (363), Expect = 6e-35
Identities = 95/289 (32%), Positives = 155/289 (53%), Gaps = 15/289 (5%)
Query: 21 KTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQ--LPVQSKLGPWIASRRTEEVKKKYS- 77
+ A+V+ N+GGP+T + V +L + D +I+ LPV+ + I++ R VK+ Y+
Sbjct: 4 RIAVVLFNLGGPDTGNDVQPFLKNLFRDPAIIRAPLPVRWLVARLISTLRAPVVKQNYAM 63
Query: 78 -EIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGAD 136
+ GGGSP+L+ T Q L L + LP + ++A RY PFTE+A EV+ GAD
Sbjct: 64 MDAGGGSPLLRETKKQADALQAELAKKLPGDEV-RCFIAMRYWHPFTEEAAAEVQKWGAD 122
Query: 137 RVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKE 196
V++ YPQ+S TTGSSL+A Y+ ++ + E + S + ++I
Sbjct: 123 EVVLLPLYPQFSTTTTGSSLSAWHKAYKGKSRTI-CCYPFEENFVSAHV------DQIMA 175
Query: 197 KLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQS 256
++ +V +L +AH LP V GD Y + + + + +QS
Sbjct: 176 AWERAGRP--GNVNLLLSAHGLPESVVKSGDPYQWQCEALAEMIAGRVPADWEVSVCYQS 233
Query: 257 KVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEY 305
+VGP+ W+ P T++ I + QG +++++ P+AFV+EHIETL EL EY
Sbjct: 234 RVGPMKWIGPPTEEEIARISDQG-RNILIAPIAFVSEHIETLVELGEEY 281
>UniRef50_Q5PA48 Cluster: Ferrochelatase; n=2; Anaplasma|Rep:
Ferrochelatase - Anaplasma marginale (strain St. Maries)
Length = 350
Score = 147 bits (356), Expect = 4e-34
Identities = 99/291 (34%), Positives = 154/291 (52%), Gaps = 14/291 (4%)
Query: 21 KTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKL--GPWIASRRTEEVKKKYSE 78
K A+V+LN+GGP + +V +L + +DR ++ LP ++ I+ R +K YS
Sbjct: 8 KVAVVLLNLGGPGSLCEVEKFLFSLFSDRRILGLPYPLRMLVAMIISKLRARSARKIYSL 67
Query: 79 IGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRV 138
+GG S IL+ T Q S L + L+ +K +V R+ P + +A V + V
Sbjct: 68 MGGKSTILEETEHQASALEKRLNSSAAGKI-YKVFVCMRHSKPGSREALHAVRDYQPEHV 126
Query: 139 IIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFS-LIERWASHKLLAKVFSERIKEK 197
++ YPQYS TT L+AI D+ + + +I + +HK + K
Sbjct: 127 VLLPMYPQYSSTTT---LSAIEDWNNSARKACYAPDTRIICCYHTHK---DYIAAHCKLI 180
Query: 198 LDKFDEKI--RDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRN-PHRLVW 254
LD++++ ILF+AH LP+ V RGD Y ++ +V +E+LG R + + +
Sbjct: 181 LDEYNKAAMGHSSPRILFSAHGLPVHIVKRGDPYQEQIRQSVCAIVEQLGIRALDYSICY 240
Query: 255 QSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEY 305
QSKVGP WL+P T I L AK +++VP++FV+EH ETL ELDIEY
Sbjct: 241 QSKVGPTQWLEPSTQLEI-LRAKDDGVPVVVVPISFVSEHSETLVELDIEY 290
>UniRef50_A6QAW0 Cluster: Ferrochelatase; n=1; Sulfurovum sp.
NBC37-1|Rep: Ferrochelatase - Sulfurovum sp. (strain
NBC37-1)
Length = 316
Score = 146 bits (354), Expect = 7e-34
Identities = 101/302 (33%), Positives = 162/302 (53%), Gaps = 23/302 (7%)
Query: 19 KPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQL-PVQSK-LGPWIASRRTEEVKKKY 76
K K A+++LNMGGP T ++V +L + DR+++ + PV K + I S+R E+VK+ Y
Sbjct: 3 KMKQALLLLNMGGPNTIEEVELFLRNMFADRNILTMNPVMRKFIANIIISKRLEDVKENY 62
Query: 77 SEIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGAD 136
+GG SP+ + T + L LD LP Y A RYVPPF + A + DG +
Sbjct: 63 RLLGGKSPLPELTERLIAKLKTRLD--LPV------YPAMRYVPPFADKALYACQKDGVE 114
Query: 137 RVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKE 196
+I+F YPQYS TT SS+ I + R K ++I+ + + E+I E
Sbjct: 115 ELILFPMYPQYSTTTTLSSIEDIEE--RCEAMGYAPKITVIDPYYDDYTYIEACCEKILE 172
Query: 197 KLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVS--RTMEELGGRNPH--RL 252
+ + K D +L +AH LP+ + GD Y ++V S +T G + H +L
Sbjct: 173 VAEGKETKEYD---LLLSAHGLPMSIIKAGDPYQNQVEGNASAIKTYLACKGVDFHDIKL 229
Query: 253 VWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVAKE 312
V+QSKVG WL+P D ++ + +++ P+AF ++ ET+ ELDIE+ E+A++
Sbjct: 230 VYQSKVGSSAWLEPNLVDVLR---NPTHRKVLIYPLAFTLDNSETVFELDIEH-REIAEK 285
Query: 313 LR 314
++
Sbjct: 286 IK 287
>UniRef50_A6Q2Y9 Cluster: Ferrochelatase; n=2;
Epsilonproteobacteria|Rep: Ferrochelatase -
Nitratiruptor sp. (strain SB155-2)
Length = 309
Score = 141 bits (341), Expect = 3e-32
Identities = 99/298 (33%), Positives = 159/298 (53%), Gaps = 26/298 (8%)
Query: 23 AIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKL-----GPWIASRRTEEVKKKYS 77
AIV+LNMGGP ++V +L + D+++ LP+++ L I R +E + Y
Sbjct: 3 AIVLLNMGGPNNLEEVELFLRNMFNDKNI--LPIRNDLLRKFVAYMITQGRKKEARSNYE 60
Query: 78 EIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADR 137
++GG SP+ +T+ L L + LP+ K A RY PPF ++A +E+
Sbjct: 61 KLGGKSPLNFYTDR----LIAKLQKRLPDVYVTK---AMRYTPPFAKEAIKELMYHNVRE 113
Query: 138 VIIFSQYPQYSCATTGSSLNAIADFYR-NRTTPANVKFSLIERWASHKLLAKVFSERIKE 196
V + YP YS TT SSL DFY + + +F I + ++L + ERI+E
Sbjct: 114 VFLIPLYPHYSTTTTKSSLE---DFYNMAKGVGYHARFHDIANFYENRLYNQAIIERIEE 170
Query: 197 KLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGR-NPHRLVWQ 255
LD D K + ++F+AHSLP K + +GD Y EV V L + + + L +Q
Sbjct: 171 ALDGEDTK---EYELVFSAHSLPQKIIEKGDPYLQEVQEHVKILTSILEEKFSGYHLAFQ 227
Query: 256 SKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVAKEL 313
SK+GP+ WL+P D+ KL +G K +++ P++F ++ ET EL IEY ++A+++
Sbjct: 228 SKLGPVKWLEPGLDE--KLEELKG-KKILVYPISFTLDNSETEFELHIEYA-QIAQKI 281
>UniRef50_A7T926 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 249
Score = 140 bits (339), Expect = 5e-32
Identities = 64/130 (49%), Positives = 88/130 (67%), Gaps = 1/130 (0%)
Query: 20 PKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVKKKYSEI 79
PKT I++LN+GGPE + V +L R+ +D+D+I LP Q +L WIA RRT ++K++Y +I
Sbjct: 1 PKTGILLLNLGGPEKQEDVHGFLLRLFSDKDLIPLPAQKQLAAWIAKRRTPKIKEQYQKI 60
Query: 80 GGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVES-DGADRV 138
GGGSPI WT QG + + LDQ+ PE+APHK YV FRY P TEDA ++E V
Sbjct: 61 GGGSPIKMWTEKQGQGMVELLDQLSPETAPHKFYVGFRYATPLTEDAIEQMERYTLVLEV 120
Query: 139 IIFSQYPQYS 148
+Q+PQ+S
Sbjct: 121 WRNAQFPQWS 130
Score = 128 bits (308), Expect = 3e-28
Identities = 59/94 (62%), Positives = 71/94 (75%)
Query: 220 LKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQSKVGPLPWLQPYTDDAIKLYAKQG 279
L + RGD YP EVA+TV R ME L + +RLVWQSKVGPLPWL P T+DAIK AK
Sbjct: 145 LSRLDRGDPYPQEVAATVQRVMEALDFSHSYRLVWQSKVGPLPWLGPQTEDAIKGLAKNN 204
Query: 280 VKHLILVPVAFVNEHIETLHELDIEYCDEVAKEL 313
K+L+LVP+AF ++HIETLHELDIEY E+A E+
Sbjct: 205 KKNLLLVPIAFTSDHIETLHELDIEYAQELAHEV 238
>UniRef50_Q5GRR7 Cluster: Ferrochelatase; n=1; Wolbachia
endosymbiont strain TRS of Brugia malayi|Rep:
Ferrochelatase - Wolbachia sp. subsp. Brugia malayi
(strain TRS)
Length = 340
Score = 139 bits (336), Expect = 1e-31
Identities = 98/311 (31%), Positives = 157/311 (50%), Gaps = 31/311 (9%)
Query: 21 KTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSK--LGPWIASRRTEEVKKKYSE 78
K A+V+LN+GGP++ V +L + D+ +I LP + L +I+++R +K Y +
Sbjct: 2 KKAVVLLNLGGPDSLSAVRPFLFNLFYDKRIINLPNPFRFFLAKFISAKRENNARKIYEQ 61
Query: 79 IGGGSPILKWTNSQGSLLTQALDQML---PESA---PHKH-----------------YVA 115
IGG SPIL+ T Q L + L++ + P S P K ++
Sbjct: 62 IGGKSPILENTKMQAEALERELNRSVFCHPSSVTLGPRKENWIPVSRIGMTSKLTKVFIC 121
Query: 116 FRYVPPFTEDAFREVESDGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFS 175
RY PF + + V+ D VI+ YPQYS TT SS+ + N K
Sbjct: 122 MRYWHPFANEVVKSVKQFDPDEVILLPLYPQYSTTTTLSSIENWQKNAKQYGIKCNTK-- 179
Query: 176 LIERWASHKLLAKVFSERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVAS 235
+I ++ + + I + E + V LF+AHSLPL + +GD Y +V
Sbjct: 180 IIRHHYDNQDFIEAHANLITKHYKLASEVGKPRV--LFSAHSLPLSVIKKGDPYALQVEE 237
Query: 236 TVSRTMEELGGRN-PHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEH 294
TV +++L ++ + +QSK+GP+ WL+P T+ + L AK ++L+P++FV+EH
Sbjct: 238 TVKLIVKKLHIKDLDWSICYQSKIGPVKWLEPSTESEL-LRAKADGVPVVLLPISFVSEH 296
Query: 295 IETLHELDIEY 305
ETL ELD+EY
Sbjct: 297 SETLVELDMEY 307
>UniRef50_Q2GH68 Cluster: Ferrochelatase; n=3; canis group|Rep:
Ferrochelatase - Ehrlichia chaffeensis (strain Arkansas)
Length = 343
Score = 139 bits (336), Expect = 1e-31
Identities = 96/299 (32%), Positives = 154/299 (51%), Gaps = 12/299 (4%)
Query: 18 VKPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQL--PVQSKLGPWIASRRTEEVKKK 75
V K A+V+ N+GGP++ +V +L + D+++I + P++ L ++ R + +
Sbjct: 6 VSKKVAVVLFNLGGPQSLCEVRPFLFNLFYDKNIINISNPLRFILATLLSFFRKRKAIEI 65
Query: 76 YSEIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGA 135
Y + G SPIL T Q S L L+ +K ++ R+ P + + V
Sbjct: 66 YKHLNGQSPILSETKIQASSLEHILNNH--NENQYKVFIFMRHSKPSAKSTIKSVCQYRP 123
Query: 136 DRVIIFSQYPQYSCATTGSSLNAIADF-YRNRTTPANVKFSLIERWASHKLLAKVFSERI 194
D++I+ YP YS TT L+AI + Y + + + S I + +++ K + I
Sbjct: 124 DKIILIPLYPHYSTTTT---LSAIQHWNYHMKKSRFHCPTSTICCYYNNENYIKAHCQLI 180
Query: 195 KEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELG-GRNPHRLV 253
EK + ILF+AHSLPL V RGD Y H++ TV + L +++
Sbjct: 181 IEKYREAQNY--GSPRILFSAHSLPLSIVQRGDPYQHQIEQTVLLITKSLNISSLDYKIC 238
Query: 254 WQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVAKE 312
+QSKVG + WL+P T AI AKQ ++LVP++FV+E+ ETL ELDIE ++KE
Sbjct: 239 YQSKVGNIKWLEPSTISAIN-QAKQDDVPIVLVPISFVSENSETLVELDIECKKIISKE 296
>UniRef50_Q2GCY1 Cluster: Ferrochelatase; n=1; Neorickettsia
sennetsu str. Miyayama|Rep: Ferrochelatase -
Neorickettsia sennetsu (strain Miyayama)
Length = 325
Score = 135 bits (326), Expect = 2e-30
Identities = 97/289 (33%), Positives = 147/289 (50%), Gaps = 23/289 (7%)
Query: 21 KTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSK--LGPWIASRRTEEVKKKYSE 78
K A+V+LN+GGP++ D V +L + DR +I LP + L WI+ +R E K YS+
Sbjct: 3 KVAVVLLNLGGPDSLDAVRPFLFNLFCDRRIINLPNPFRFCLAWWISRKRFREACKIYSK 62
Query: 79 IGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRV 138
+GG S IL TN Q LL L P+ ++ +VA R+ PF + + + +
Sbjct: 63 MGGKSSILPETNMQAKLLGDLLG---PQ---YEVFVAMRHWHPFIQQSATRINGGEFAKA 116
Query: 139 IIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKL 198
I+ YPQ+S T+ SS+ R T ++ + ++L + E I L
Sbjct: 117 ILLPLYPQFSTTTSLSSIEQCLKVLRIPT-------QVVCCYYDNQLFIEAHVETI---L 166
Query: 199 DKFDEKIR-DDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRN-PHRLVWQS 256
+ E +ILF+AH LPL + GD Y +V V R + L N L +QS
Sbjct: 167 PIYAEACAFGKPIILFSAHGLPLSVIKAGDPYKFQVEEFVRRVVAALKIENLDWELCYQS 226
Query: 257 KVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEY 305
+VG WL P T I+ ++++ + ++VP+AFV+EH ET ELDIEY
Sbjct: 227 RVGKAKWLCPDTASTIQSHSERPI---VVVPIAFVSEHSETRVELDIEY 272
>UniRef50_Q9RV98 Cluster: Ferrochelatase; n=1; Deinococcus
radiodurans|Rep: Ferrochelatase - Deinococcus
radiodurans
Length = 316
Score = 124 bits (300), Expect = 2e-27
Identities = 84/302 (27%), Positives = 145/302 (48%), Gaps = 26/302 (8%)
Query: 16 TAVKPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVKKK 75
T KP ++ + GGPE ++ YL I R Q + +E+
Sbjct: 5 TNQKP-LGVLFMAYGGPENLGEMPGYLADIRAGRVTSQAIL-------------DEITNN 50
Query: 76 YSEIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGA 135
Y IGG SP+ ++T +Q + ++Q+ P K Y+ R+ P+ EDA RE+ DG
Sbjct: 51 YRLIGGKSPLPEFTRAQ---VEATMEQLASTGRPLKAYIGMRHWSPWIEDAVREMLDDGI 107
Query: 136 DRVIIFSQYPQYSCATTGSSLNAI-ADFYRNRTTPANVKFSLIERWASHKLLAKVFSERI 194
++ I PQYS + I A N ++ F+ I+ + + ++R+
Sbjct: 108 EQAIAIVLAPQYSSLSVAKYQKKIKAALEMNH---GHIDFAYIDNYHTEPGYITALADRV 164
Query: 195 KEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVW 254
+ + +F E RDDV ++ +AHSLP++ + GD Y ++ T +R + G + W
Sbjct: 165 RIGIQEFPEDERDDVHVILSAHSLPVRIIKEGDPYADQLHET-ARLVAAQAGLTDEQWSW 223
Query: 255 QSKV---GPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVAK 311
+ P PWL P D+ ++ +QG+K ++ + + FV++H+E L ++DI EVA
Sbjct: 224 SYQSAGRSPEPWLGPQLDEHLRDLNEQGIKKVVSIAIGFVSDHVEILFDIDIA-AQEVAH 282
Query: 312 EL 313
EL
Sbjct: 283 EL 284
>UniRef50_Q833G5 Cluster: Ferrochelatase; n=1; Enterococcus
faecalis|Rep: Ferrochelatase - Enterococcus faecalis
(Streptococcus faecalis)
Length = 313
Score = 121 bits (291), Expect = 3e-26
Identities = 86/291 (29%), Positives = 150/291 (51%), Gaps = 22/291 (7%)
Query: 21 KTAIVMLNMGGPETTD--QVGDYLHRIMTDRDMIQL-PVQSK--LGPWIASRRTEEVKKK 75
+T I+++N+G P+ + +V YL ++DR +I++ P+ K L I + R ++ K
Sbjct: 3 RTGILLVNLGTPKDSSKTEVRKYLKTFLSDRRVIKIHPIIWKPILNGIILNIRPKKSAKL 62
Query: 76 YSEI--GGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESD 133
Y +I G P+L++T Q + L + PE + + Y P E A + S
Sbjct: 63 YQKICTENGFPLLEYTEKQ----MENLKNICPEV---EVTIGMSYSEPSIETALDTLLSK 115
Query: 134 GADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSER 193
+ + + YPQYS T GS +++ +++ ++KF I + ++ FS++
Sbjct: 116 EIEELNVIPMYPQYSGTTVGSVFDSVMNYFIKSDRIVDIKF--IRSFYNNPQYIDYFSKK 173
Query: 194 IKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLV 253
I E L+ E D I+F+ H +P+ V GD YP E T M++LG ++
Sbjct: 174 INEALN---ESPID--AIVFSYHGIPMSYVKDGDNYPKECTKTTKLIMDKLGDIRYYQ-T 227
Query: 254 WQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIE 304
+QSK GP WL+P TDD +K +G+K++++V FV + +ET+ EL+ E
Sbjct: 228 YQSKFGPSEWLKPATDDTLKKLPSKGIKNILIVAPGFVVDCLETIEELEHE 278
>UniRef50_Q7VHH1 Cluster: Ferrochelatase; n=1; Helicobacter
hepaticus|Rep: Ferrochelatase - Helicobacter hepaticus
Length = 311
Score = 118 bits (284), Expect = 2e-25
Identities = 90/293 (30%), Positives = 140/293 (47%), Gaps = 25/293 (8%)
Query: 29 MGGPETTDQVGDYLHRIMTDRDMIQLP---VQSKLGPWIASRRTEEVKKKYSEIGGGSPI 85
MG P + +V +L + D ++ + + L +I R EE KK Y IGG SP+
Sbjct: 1 MGSPNSLFEVESFLKNMFNDPLILGIKNTFARKMLASFITHSRVEETKKNYQAIGGKSPL 60
Query: 86 LKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRVIIFSQYP 145
T + LT L+++ + A RY PPF ++++ G V++FS YP
Sbjct: 61 TAHTLN----LTNKLNEL---DCKRFYTYAMRYTPPFAYQVLEDIKTQGIQSVVLFSLYP 113
Query: 146 QYSCATTGSSL-NAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKLDKFDEK 204
Q+S +T SSL +A A + TP + I + +H ERIKE L +
Sbjct: 114 QFSYSTIASSLIDAKAALQKLAFTPTLYE---ISSYHTHPDYISCIIERIKESLGADNP- 169
Query: 205 IRDDVLILFTAHSLPLKAVSRGDTYP---HEVASTVSRTMEELG-GRNPHRLVWQSKVGP 260
++ ++L +AHSLP + GD Y E + + +E G L +QSKVG
Sbjct: 170 --NEFVLLLSAHSLPQSRIDEGDPYQKQCEENKEVIQKALESEGIVFKKIALAYQSKVGR 227
Query: 261 LPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVAKEL 313
+ W+ P T + I Y K +I+ P++F ++ ET +EL I Y +AKEL
Sbjct: 228 MKWIGPSTKETITKYKKH---KMIIFPLSFTLDNSETEYELKILYA-SLAKEL 276
>UniRef50_Q8GCV0 Cluster: Ferrochelatase; n=1; Leptospira
biflexa|Rep: Ferrochelatase - Leptospira biflexa
Length = 362
Score = 118 bits (283), Expect = 3e-25
Identities = 93/310 (30%), Positives = 153/310 (49%), Gaps = 30/310 (9%)
Query: 19 KPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQS----KLGPWIASRRTEEVKK 74
K KT ++++N+GGP T ++ +L + +D + LP+ +L +IA +R +V+K
Sbjct: 5 KVKT-LILVNLGGPRTPSEIEVFLRDLFSDPFVFDLPLPEFLRLRLARFIAKKRAPKVQK 63
Query: 75 KYSEIG--GGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVES 132
Y +G GGSP+++ T Q L AL++ E K +A Y P + F +
Sbjct: 64 SYESMGFGGGSPLVEETAKQAHALELALNERSSEQWNVKVAMACGY-PNMRDIEFGKPNQ 122
Query: 133 DGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPAN---VKFSLIERWASHKLLAKV 189
D + YPQ+S +T S+L + + + F L + H + AK
Sbjct: 123 D----TVYLPLYPQFSRSTVLSTLAILETKFGECPVGSGGYVPHFGLDPNF--HSISAKF 176
Query: 190 FSERIKEKLDKF------DEKIRDD---VLILFTAHSLPLKAVSRGDTYPHEVASTVSRT 240
E +L K +EK D + ++F+AH +P++ + +GD Y EV +V
Sbjct: 177 IYEFFTNQLPKDQYLHYPEEKPNCDWRNLDLVFSAHGVPMRLIHKGDRYMEEVELSVKGI 236
Query: 241 MEEL---GGRNPHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIET 297
+EL G + +QSKVGP W +P T I AKQG KH+ + P++FV++HIET
Sbjct: 237 ADELSKFGFNGGVHISYQSKVGPAKWTEPSTIQMISSLAKQG-KHIAVYPISFVSDHIET 295
Query: 298 LHELDIEYCD 307
L E+ ++ D
Sbjct: 296 LEEIGEQFKD 305
>UniRef50_Q9PI08 Cluster: Ferrochelatase; n=16; Campylobacter|Rep:
Ferrochelatase - Campylobacter jejuni
Length = 303
Score = 118 bits (283), Expect = 3e-25
Identities = 85/286 (29%), Positives = 138/286 (48%), Gaps = 22/286 (7%)
Query: 24 IVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQ--SKLGPWIASR-RTEEVKKKYSEIG 80
++ LNMGG +L + D ++ + + K WI ++ R + +++ Y ++G
Sbjct: 4 VLFLNMGGATNLQDCEVFLKNMFNDPYILGIKNRFLRKFVAWIITKARVKAMQENYKKMG 63
Query: 81 GGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRVII 140
G SP+ + T S L D+ K YVPPF + ++ + +D +I+
Sbjct: 64 GKSPLNELTQSLCDKLNLKQDEF-------KFDFVNLYVPPFATEILQKYTLNASDEIIL 116
Query: 141 FSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKLDK 200
F YP +SC T SSL + + + A VK I+ + ++L ++ I K K
Sbjct: 117 FPLYPHHSCTTVTSSLEVLQNEISKQKIQAKVK--TIDIFYKNELYNEMIVSHILAKKSK 174
Query: 201 FDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGR-NPHRLVWQSKVG 259
FD KI ++F+AHSLP + +GD Y V V E+L + L +QSK+G
Sbjct: 175 FDAKI-----LIFSAHSLPQSIIDKGDLYEKHVNDHVEILKEKLKDHFDEFILAYQSKLG 229
Query: 260 PLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEY 305
P+ WL+P T D + A K LI P++F + ET+ EL +EY
Sbjct: 230 PVKWLEPNTSDVL---ANLNDKALI-YPISFCIDCSETIFELGMEY 271
>UniRef50_Q1NMT4 Cluster: Ferrochelatase; n=2; delta proteobacterium
MLMS-1|Rep: Ferrochelatase - delta proteobacterium
MLMS-1
Length = 388
Score = 116 bits (278), Expect = 1e-24
Identities = 69/201 (34%), Positives = 110/201 (54%), Gaps = 12/201 (5%)
Query: 115 AFRYVPPFTEDAFREVESDGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKF 174
A RY PF ++A E G +++ YP +S ATTGSSLN D R T + F
Sbjct: 167 AMRYWHPFVDEALAEFRQAGVRQLLALPLYPHFSRATTGSSLN---DLRRALATHDDF-F 222
Query: 175 SL--IERWASHKLLAKVFSERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHE 232
+ I W + SE I++ F ++ +L++AHSLP+ + GD Y
Sbjct: 223 TCREINAWPAQPDYLAALSETIEQGAAAFGT---EEYTLLYSAHSLPVSFIEDGDPYLEH 279
Query: 233 VASTVSRTMEELGGRNPHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVN 292
+ T++ LG L +QS+ GP+ WL P T + + A +GVK+++LVP++FV+
Sbjct: 280 IKKTIAGLEARLGRSG--ELCFQSRSGPVRWLSPSTPEMLAQLAGRGVKNVLLVPISFVS 337
Query: 293 EHIETLHELDIEYCDEVAKEL 313
+H+ETL+E+D++Y E+A+ L
Sbjct: 338 DHVETLYEIDLQY-HELARGL 357
Score = 58.4 bits (135), Expect = 2e-07
Identities = 29/85 (34%), Positives = 48/85 (56%), Gaps = 4/85 (4%)
Query: 21 KTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLP----VQSKLGPWIASRRTEEVKKKY 76
+ +V+LNMGGPE D+V +L + DR++I+L +Q + I +R + ++ Y
Sbjct: 32 RIGVVLLNMGGPEKLDEVEPFLRNLFNDREIIRLGPFPWLQKLIAGRIVKKRAPKSREAY 91
Query: 77 SEIGGGSPILKWTNSQGSLLTQALD 101
IGGGSP+ + + QG L L+
Sbjct: 92 RRIGGGSPLARISAEQGRALAARLN 116
>UniRef50_A6VXF8 Cluster: Ferrochelatase; n=1; Marinomonas sp.
MWYL1|Rep: Ferrochelatase - Marinomonas sp. MWYL1
Length = 330
Score = 116 bits (278), Expect = 1e-24
Identities = 82/293 (27%), Positives = 141/293 (48%), Gaps = 16/293 (5%)
Query: 24 IVMLNMGGPET--TDQVGDYLHRIMTDRDMIQL-PVQSK--LGPWIASRRTEEVKKKYSE 78
++M+N+G P+ T +V YL ++D ++ L P+ K L I + R +V K Y +
Sbjct: 9 VLMMNLGTPDAPQTPEVRRYLREFLSDSRVVDLNPLIWKPILNLIILTIRPPKVAKIYQQ 68
Query: 79 I--GGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGAD 136
+ GSP+L + + +AL + ++ P + +A Y P E A ++ G
Sbjct: 69 VWMDEGSPLLVLSERLKEKVKEALSEKKGQTVPVE--LAMTYGNPSVEVAANKLREQGVK 126
Query: 137 RVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKE 196
+I+ YPQ+S TT ++ + + +N P L+ +A H + K S ++
Sbjct: 127 NIIVIPMYPQFSATTTAAAYDRLMKSLKN--CPHWPSLQLLHDYADHPMYIKALSNSVRA 184
Query: 197 KLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELG-GRNPHRLVWQ 255
+ DK E+ ++ + H +P + V+ GD Y +T EEL G + V+Q
Sbjct: 185 QWDKQGERRH----LVLSYHGIPKRYVTNGDPYARRCETTSRLVAEELELGDHEWTHVYQ 240
Query: 256 SKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDE 308
S+ G WL+PY D +K GVK + ++ AF + IETL E+ +E DE
Sbjct: 241 SRFGREEWLKPYADATLKALPSMGVKKINIISPAFSIDCIETLEEVTLELGDE 293
>UniRef50_A6DEA9 Cluster: Ferrochelatase; n=1; Caminibacter
mediatlanticus TB-2|Rep: Ferrochelatase - Caminibacter
mediatlanticus TB-2
Length = 298
Score = 113 bits (271), Expect = 8e-24
Identities = 82/292 (28%), Positives = 144/292 (49%), Gaps = 29/292 (9%)
Query: 21 KTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVKKKYSEIG 80
K AI++ NMGG D++ ++L + D+ ++ P + + P IA+ R ++V + Y +IG
Sbjct: 2 KRAIILHNMGGARNKDELREFLLNMFKDKRILNSPFRKIIAPIIANLRYKKVWENYKKIG 61
Query: 81 GGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRVII 140
G S+ +T+ L + + ++ A RY P+ + E +I
Sbjct: 62 G---------SRIYTITENLCNEMQKYTDYEVVYAMRYTKPYLNKIIHKYEE-----IIF 107
Query: 141 FSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKLDK 200
YP YS T S L D +N VK +I + ++ ++ E I +++D
Sbjct: 108 LPLYPHYSFTTFESCL----DDLKNTNFKGKVK--IINPFFENEKFNEIIKENILKEVDN 161
Query: 201 FDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQSKVGP 260
E ++F+AH +P K +++GD Y + S V ++L L +QS+ GP
Sbjct: 162 PKEWN-----LIFSAHGIPKKLINKGDKYYSHILSHVEILKKKLSEFKSINLAFQSRFGP 216
Query: 261 LPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVAKE 312
L WL+PY ++ +K Y + V ++ P++F+ ++ ET EL IEY E+AKE
Sbjct: 217 LEWLKPYLNEELKKYKNENV---LVYPLSFMIDNSETDLELSIEY-KELAKE 264
>UniRef50_A5UU36 Cluster: Ferrochelatase; n=3; Chloroflexi
(class)|Rep: Ferrochelatase - Roseiflexus sp. RS-1
Length = 313
Score = 113 bits (271), Expect = 8e-24
Identities = 85/305 (27%), Positives = 137/305 (44%), Gaps = 22/305 (7%)
Query: 16 TAVKPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVKKK 75
T P + +L G PE+ D V Y I R K P E ++++
Sbjct: 2 THTSPPVGVFLLAYGTPESLDDVEPYFTHIRGGR---------KPSP----EAVENLRER 48
Query: 76 YSEIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGA 135
Y +GG +P+ T + L LD P ++ YV ++ PF + + +DG
Sbjct: 49 YRLVGGRTPLKDLTFATADKLQARLDAEAP--GRYRVYVGMKHWHPFIAETMPHIAADGV 106
Query: 136 DRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIK 195
V+ P YS + G + + N T ++ + IERW H ++ ++RI
Sbjct: 107 RDVVALVLAPHYSRMSVGGYRRYVDE--ANATLEQPLQITFIERWHDHPGFRRLIADRIV 164
Query: 196 EKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQ 255
+ + D L+LF+AHSLP + +S D YP E+ + + + L G RL +Q
Sbjct: 165 AARAELPPDLHDQALVLFSAHSLPERILSWNDPYPDELRESAA-GIAGLLGLTDWRLCYQ 223
Query: 256 SK-VGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVAK--- 311
S + PWL P D ++ +GV+ +I P FV +H+E L ++D E D+ A+
Sbjct: 224 SAGMTGEPWLGPDILDYLEELHSEGVRAVISAPFGFVADHLEVLWDIDREAQDKAAELGM 283
Query: 312 ELRTI 316
ELR I
Sbjct: 284 ELRRI 288
>UniRef50_P37408 Cluster: Ferrochelatase; n=5;
Enterobacteriaceae|Rep: Ferrochelatase - Salmonella
typhimurium
Length = 320
Score = 113 bits (271), Expect = 8e-24
Identities = 84/291 (28%), Positives = 137/291 (47%), Gaps = 25/291 (8%)
Query: 21 KTAIVMLNMGGPE--TTDQVGDYLHRIMTDRDMIQLPVQ---SKLGPWIASRRTEEVKKK 75
KT I++ N+G P+ T + V YL + ++DR ++ P L I R+ V K
Sbjct: 5 KTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTPRLLWWPLLRGVILPLRSPRVAKL 64
Query: 76 YSEI--GGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESD 133
Y I GGSP++ ++ Q QAL LP++ + Y P E A E+ +
Sbjct: 65 YQSIWMDGGSPLMVYSREQ----QQALAARLPDTPVA---LGMSYGSPSLESAVDELLAS 117
Query: 134 GADRVIIFSQYPQYSCATTGSSLNAIADFY-RNRTTPANVKFSLIERWASHKLLAKVFSE 192
D +++ YPQYSC+T G+ + + R R P S I +A ++
Sbjct: 118 DVDHIVVLPLYPQYSCSTVGAVWDELGRILARKRRIPG---ISFIRDYADDGAYIDALAK 174
Query: 193 RIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRL 252
+E + E DVL+L + H +P + GD YP T + LG P ++
Sbjct: 175 SARESFARHGEP---DVLLL-SYHGIPQRYADEGDDYPQRCRDTTRELVSALG-LPPEKV 229
Query: 253 V--WQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHEL 301
+ +QS+ G PWL PYTD+ +K+ ++G H+ ++ F + +ETL E+
Sbjct: 230 MMTFQSRFGREPWLTPYTDETLKMLGEKGTGHIQVMCPGFAADCLETLEEI 280
>UniRef50_P57874 Cluster: Ferrochelatase; n=1; Pasteurella
multocida|Rep: Ferrochelatase - Pasteurella multocida
Length = 326
Score = 113 bits (271), Expect = 8e-24
Identities = 83/294 (28%), Positives = 134/294 (45%), Gaps = 20/294 (6%)
Query: 19 KPKTAIVMLNMGGPE--TTDQVGDYLHRIMTDRDMIQLPVQS---KLGPWIASRRTEEVK 73
K KT ++++N+G PE T + YL + +TD ++ LP L I R + V
Sbjct: 3 KAKTGVLLVNLGTPESPTPKAISRYLWQFLTDPRVVDLPRYKWFPLLKGIILPLRAKRVA 62
Query: 74 KKYSEIGG--GSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVE 131
K Y+ I GSP+L T Q L Q VA Y P + A + +
Sbjct: 63 KNYASIWTEQGSPLLTITREQQHALQTYFKQQEKNIVVE---VAMTYGEPSIKSAMQRLS 119
Query: 132 SDGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFS 191
+ D +I+F YPQYS +TTG+ +A A +T + F I + +++
Sbjct: 120 TQQVDNLIVFPLYPQYSSSTTGAVFDAFAQVL--KTQRGVLPFDFIHSYHTNE------- 170
Query: 192 ERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELG-GRNPH 250
+ I + E + D +LF+ H +P++ + GD Y TV ++ LG N
Sbjct: 171 DYIAALVTTIQEHFQPDEFLLFSFHGIPVRYENMGDYYREHCKQTVLAVIDRLGLTENQW 230
Query: 251 RLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIE 304
L +QS+ G WLQPYTD + Q ++ + ++ F + +ETL E++ E
Sbjct: 231 GLSFQSRFGKEEWLQPYTDQFLAQAPSQNIQKMAVICPGFAADCLETLEEIEEE 284
>UniRef50_UPI0000DAE46A Cluster: hypothetical protein
Rgryl_01000362; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01000362 - Rickettsiella
grylli
Length = 318
Score = 111 bits (266), Expect = 3e-23
Identities = 77/293 (26%), Positives = 137/293 (46%), Gaps = 20/293 (6%)
Query: 21 KTAIVMLNMGGPE--TTDQVGDYLHRIMTDRDMIQLPV---QSKLGPWIASRRTEEVKKK 75
K ++++N+G P TT V YL ++DR +++ P Q L +I +R + K
Sbjct: 2 KQGVLLVNLGTPSQPTTQAVRRYLSEFLSDRRVVEYPQWLWQIVLKLFILPKRARYLAKL 61
Query: 76 YSEI--GGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESD 133
Y I GSP+ T LT+ + L ++ ++ RY P E + + +
Sbjct: 62 YQTIWMDEGSPLAVITQR----LTEKMQTYLGDN--YQLIGVMRYGTPTIESGLKTLLAQ 115
Query: 134 GADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSER 193
G + I YPQYS TT S + I+ F++ ++K W + + + +
Sbjct: 116 GVTTITILPLYPQYSATTTASCFDQISQFFQTSRVIPHIK------WITSYFDQRWYIKA 169
Query: 194 IKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELG-GRNPHRL 252
I ++ K K +LF+ H LP + + GD Y STV E+L ++ +++
Sbjct: 170 IVSQIKKMRAKQSQPSYLLFSFHGLPQRYIENGDPYQQHCFSTVRLIAEQLQLTKDTYQV 229
Query: 253 VWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEY 305
V+QS+ G WL+PY D ++ +G+K++ ++ F + +ETL E+ Y
Sbjct: 230 VFQSRFGKTAWLKPYCDRVLQTLPARGIKNVTIICPGFAVDCLETLEEISKRY 282
>UniRef50_Q81TU9 Cluster: Ferrochelatase 2; n=76; Bacillales|Rep:
Ferrochelatase 2 - Bacillus anthracis
Length = 319
Score = 111 bits (266), Expect = 3e-23
Identities = 83/297 (27%), Positives = 135/297 (45%), Gaps = 23/297 (7%)
Query: 19 KPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVKKKYSE 78
K K ++++ G P++ D+V Y I R + +Q +G +Y
Sbjct: 3 KKKIGLLVMAYGTPDSLDEVEAYYTHIRHGRKPSEEALQDLIG-------------RYKA 49
Query: 79 IGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRV 138
IGG SP+ K T Q LT +++ M E Y+ ++ PF EDA E++ DG ++
Sbjct: 50 IGGISPLAKITKEQAHKLTDSMNNMFTEYE-FNCYLGLKHTAPFIEDAVEEMKRDGIEQA 108
Query: 139 IIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKL 198
I P YS + + N A R I++W ++++IKE
Sbjct: 109 ISIVLAPHYSTFSI-KAYNERA--IRLSEEIGGPVIKPIDQWYDEPKFISYWADQIKETF 165
Query: 199 DKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQSKV 258
K ++K + +++F+AHSLP K ++ GD Y ++ T +N + + WQS
Sbjct: 166 TKIEDK--EKAVVIFSAHSLPEKIIAAGDPYVEQLQHTADLIAAAANIQN-YTIGWQSAG 222
Query: 259 G-PLPWLQPYTDDAIK-LYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVAKEL 313
P PW+ P D + L+ + + I PV FV EH+E L++ D E C V EL
Sbjct: 223 NTPDPWIGPDVQDLTRDLFEEYRYESFIYCPVGFVAEHLEVLYDNDYE-CKVVTDEL 278
>UniRef50_P43868 Cluster: Ferrochelatase; n=40; Bacteria|Rep:
Ferrochelatase - Haemophilus influenzae
Length = 323
Score = 110 bits (264), Expect = 6e-23
Identities = 80/296 (27%), Positives = 141/296 (47%), Gaps = 23/296 (7%)
Query: 19 KP-KTAIVMLNMGGPE--TTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIAS----RRTEE 71
KP K +++ N+G P+ T + YL + +TD ++ LP + K P + + R++
Sbjct: 3 KPAKIGVLLANLGTPDSPTPKSISRYLWQFLTDPRVVDLP-RCKWYPLLKAIILPLRSKR 61
Query: 72 VKKKYSEIGG--GSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFRE 129
+ K Y I GSP+L + Q L LD ++ + +A Y P + A +
Sbjct: 62 IAKNYQAIWTEQGSPLLAISRQQKDALQAYLDN---QNIDTQVEIAMTYGNPSMQSAVKN 118
Query: 130 VESDGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKV 189
+ + +R+I+ YPQYS +TTG+ +A A+ + + F I + +
Sbjct: 119 LLKNQVERIIVLPLYPQYSSSTTGAVFDAFANALKEER--GLLPFDFIHSYHIDENYINA 176
Query: 190 FSERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELG-GRN 248
++ IK +L + D +LF+ H +PL+ GD Y T + +LG N
Sbjct: 177 LADSIKVRL-------KSDEFLLFSYHGIPLRYEKMGDYYREHCKQTTIAVVNKLGLTEN 229
Query: 249 PHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIE 304
R+ +QS+ G WLQPYTD ++ A Q ++ + ++ F + +ET+ E+D E
Sbjct: 230 QWRMTFQSRFGREEWLQPYTDKFLESAAAQNIQKIAVICPGFSVDCLETIEEIDEE 285
>UniRef50_Q8FTB1 Cluster: Ferrochelatase; n=24; Actinomycetales|Rep:
Ferrochelatase - Corynebacterium efficiens
Length = 377
Score = 108 bits (260), Expect = 2e-22
Identities = 78/310 (25%), Positives = 138/310 (44%), Gaps = 30/310 (9%)
Query: 23 AIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVKKKYSEIGGG 82
A+++L+ GGPE ++V +L + R I R +EV Y GG
Sbjct: 15 ALLVLSFGGPEGPEEVRPFLENVTRGRG-------------IPPERLDEVGAHYYHFGGV 61
Query: 83 SPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRVIIF- 141
SP+ + ++ ++ Y R PF +A ++ +DG ++F
Sbjct: 62 SPLNRLNKE---IIANVKAELAARGYDIPVYFGNRNWKPFDNEAAEQMAADGIRNALVFA 118
Query: 142 -SQYPQYS-CATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKLD 199
S + YS C + + P V F+ + ++ H + ++ ++E D
Sbjct: 119 TSAWGGYSGCRQYHEDIQGMRAHLEEIGAP-EVTFTKLRQFYDHPRFVRTMAQYVRESFD 177
Query: 200 KFDEKIRDDVLILFTAHSLPLKAVSR------GDTYPHEVASTVSRTMEELGGRNPHRLV 253
K E +RD+ ++FTAHS+PL + G Y +V + + E G + +V
Sbjct: 178 KLPEDLRDEARLVFTAHSIPLNSKDADGNPIDGSIYSRQVEESSALIARE-AGIDDFDVV 236
Query: 254 WQSKVGP--LPWLQP-YTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVA 310
WQS+ G +PWL+P D A++L G K L++ PV F+++H+E + +LD E DE
Sbjct: 237 WQSRSGSPHVPWLEPDIVDHAVELNENNGQKALVVCPVGFISDHMEVIWDLDSELMDEAT 296
Query: 311 KELRTISELS 320
+ I ++
Sbjct: 297 RRGMVIERVA 306
>UniRef50_Q5YU18 Cluster: Ferrochelatase; n=14; Bacteria|Rep:
Ferrochelatase - Nocardia farcinica
Length = 352
Score = 107 bits (257), Expect = 4e-22
Identities = 85/301 (28%), Positives = 137/301 (45%), Gaps = 33/301 (10%)
Query: 23 AIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVKKKYSEIGGG 82
A+++L+ GGPE + V +L + R + R EEV + Y GG
Sbjct: 5 ALLLLSFGGPERPEDVMPFLENVTRGRG-------------VPRARLEEVAQHYLHFGGV 51
Query: 83 SPILKWTNSQGSLLTQALDQMLPESAPHKH-YVAFRYVPPFTEDAFREVESDGADRVIIF 141
SPI N+ + +++ L E+ Y R P ED E+ DG ++F
Sbjct: 52 SPI----NALNRDIIAGVERELDEAGIDLPVYFGNRNWHPMVEDTVAEMARDGVTGALVF 107
Query: 142 SQYPQYSCATTGSSLNAIADFYRNRTT--PANVKFSLIERWASHKLLAKVFSERIKEKLD 199
P + D R R PA + + ++ H LL + F++ I+ L+
Sbjct: 108 ---PTSAWGGYSGCRQYHEDIERARAAVGPAAPHLTKLRQYFDHPLLIEAFADAIRAALE 164
Query: 200 KFDEKIRDDVLILFTAHSLPLKA-------VSRGDTYPHEVASTVSRTMEELGGRNPHRL 252
+ RD ++FTAHS+P+ A G+ Y +VA +R G H L
Sbjct: 165 RLPADRRDRARLVFTAHSVPVAADAAAGPPADGGELYSRQVADA-ARLCAAATGFADHDL 223
Query: 253 VWQSKVGP--LPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVA 310
VWQS+ GP +PWL+P D ++ A +GV +++ PV FV++H+E + +LD E D+ A
Sbjct: 224 VWQSRSGPPQVPWLEPDIVDHLEDLAGRGVDAVVVCPVGFVSDHLEVIWDLDNEAKDKAA 283
Query: 311 K 311
+
Sbjct: 284 E 284
>UniRef50_Q5NFT3 Cluster: Ferrochelatase; n=11; Francisella
tularensis|Rep: Ferrochelatase - Francisella tularensis
subsp. tularensis
Length = 333
Score = 107 bits (257), Expect = 4e-22
Identities = 86/304 (28%), Positives = 139/304 (45%), Gaps = 25/304 (8%)
Query: 21 KTAIVMLNMGGPETTD--QVGDYLHRIMTDRDMIQL-PVQSKLG------PWIASRRTEE 71
K AI+++N+G P+ D + YL ++D +I+ PV K+ P A +
Sbjct: 10 KQAILLVNLGTPDNYDTKSIKRYLKEFLSDPRVIEANPVLWKIILNLIILPIRAKKNVHT 69
Query: 72 VKKKYSEIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVE 131
K +++ SP+L +T + L + LD + + A RY P E + ++
Sbjct: 70 YKTVWNKQHNKSPLLFYTENLADKLDKKLDNYIVD-------YAMRYGNPSIESKIKSLQ 122
Query: 132 SDGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFS 191
GA +IIF YPQYS TT + + + +K I + +K + S
Sbjct: 123 DQGATEIIIFPLYPQYSATTTATVYDEVYRVLSKLRWQPTIKG--INPYYDNKFHIQTIS 180
Query: 192 ERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPH- 250
++IKE L K D D +LF+ H LP + +GD Y T EEL P+
Sbjct: 181 QQIKEHLKKLDS--TPDT-VLFSFHGLPKEYFDKGDPYYCHCYKTYRLVKEELQNEYPNI 237
Query: 251 --RLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDE 308
L +QS+ GP WL+PYT ++ + KQ K ++++ F + +ETL EL I +
Sbjct: 238 DFELSFQSRFGPKKWLEPYTTVKLEEFTKQN-KSVVVIAPGFSADCLETLEELAISEKEN 296
Query: 309 VAKE 312
K+
Sbjct: 297 FIKK 300
>UniRef50_Q67T48 Cluster: Ferrochelatase; n=1; Symbiobacterium
thermophilum|Rep: Ferrochelatase - Symbiobacterium
thermophilum
Length = 320
Score = 106 bits (254), Expect = 9e-22
Identities = 87/299 (29%), Positives = 137/299 (45%), Gaps = 21/299 (7%)
Query: 21 KTAIVMLNMGGPETT--DQVGDYLHRIMTDRDMIQLPVQSKLGPW---IASRRTEEVKKK 75
KTA++++N+G P D V YL + D +I P L I R V K
Sbjct: 3 KTAVLLVNLGTPSAPEPDAVRPYLAEFLGDWWVIDKPRWQWLPILHGIILRVRPPRVAKI 62
Query: 76 YSEIG--GGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESD 133
Y +I GSP+L ++ Q + L Q L+ PE + + Y P + A E+
Sbjct: 63 YQKIWLPEGSPLLHYSRLQQAALQQRLE---PEGI--RVALGMTYGQPSVKSALEELRGW 117
Query: 134 GADRVIIFSQYPQYSCATTGSSLNAIADFYRN-RTTPANVKFSLIERWASHKLLAKVFSE 192
G R+++ +PQYS TT + + + R P + I + +H +E
Sbjct: 118 GVRRLLVLPLFPQYSSTTTAAVWSKVQKALDGWRDLPEQI---FIRDFPTHPKYLAFLTE 174
Query: 193 RIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRL 252
RI + EK R D L+L + HS+P + GD Y + ST + +
Sbjct: 175 RISGYIA---EKGRPDALVL-SYHSIPQAYTASGDDYAAQCESTTDAVRDRFPDLKIV-M 229
Query: 253 VWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVAK 311
+QSK G PWL+P TD+ ++ + G +H+ ++ F + IETLHEL++EY +E K
Sbjct: 230 GYQSKFGNDPWLEPATDEVLRELVRTGHRHVAVMAPGFAADCIETLHELEVEYAEEFVK 288
>UniRef50_P43413 Cluster: Ferrochelatase; n=28;
Gammaproteobacteria|Rep: Ferrochelatase - Yersinia
enterocolitica
Length = 322
Score = 105 bits (253), Expect = 1e-21
Identities = 78/289 (26%), Positives = 133/289 (46%), Gaps = 21/289 (7%)
Query: 21 KTAIVMLNMGGPE--TTDQVGDYLHRIMTDRDMIQLPVQ---SKLGPWIASRRTEEVKKK 75
K ++M+N+G P+ T V YL ++DR ++ L I R+ V K
Sbjct: 5 KLGVLMVNLGTPDAPTPQAVKRYLAEFLSDRRVVDTSPWLWWPLLRGVILPIRSPRVAKL 64
Query: 76 YSEI--GGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESD 133
Y + GSP+L ++ Q +AL + +PE + Y P DA ++ +
Sbjct: 65 YQSVWMDEGSPLLVYSRRQ----QKALAERMPEIPVE---LGMSYGSPNLPDAIDKLLAQ 117
Query: 134 GADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSER 193
G ++++ YPQYSC+T+ + +A+A + ++ F I +A H +
Sbjct: 118 GVTKLVVLPLYPQYSCSTSAAVWDAVARILKGYRRLPSISF--IRDYAEHPAYISALKQS 175
Query: 194 IKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELG-GRNPHRL 252
++ + F + + D L+L + H +P + GD YP T E+ +
Sbjct: 176 VE---NSFVQHGKPDRLVL-SFHGIPKRYAQLGDDYPQRCEDTSRALRAEIALPAEQIMM 231
Query: 253 VWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHEL 301
+QS+ G PWL PYTD+ +K QGVKH+ L+ F + +ETL E+
Sbjct: 232 TYQSRFGREPWLTPYTDETLKSLPSQGVKHIQLICPGFSADCLETLEEI 280
>UniRef50_Q5QVZ8 Cluster: Ferrochelatase; n=17;
Gammaproteobacteria|Rep: Ferrochelatase - Idiomarina
loihiensis
Length = 364
Score = 103 bits (247), Expect = 6e-21
Identities = 84/294 (28%), Positives = 139/294 (47%), Gaps = 20/294 (6%)
Query: 21 KTAIVMLNMGGPE--TTDQVGDYLHRIMTDRDMIQLPVQSK---LGPWIASRRTEEVKKK 75
K +++ N+G PE T + YL ++D ++++P L I R + +
Sbjct: 16 KIGVLVTNLGTPEAPTKKALKPYLKEFLSDPRVVEVPRLLWFLILNGVILRFRPKRSAEA 75
Query: 76 YSEI--GGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESD 133
Y + GSP+L T Q S + L Q ++ A RY P + ++
Sbjct: 76 YKTVWTDRGSPLLFHTQDQASAIEAKLKQTWGDNIVVDF--AMRYGNPALSEVVEKMMQK 133
Query: 134 GADRVIIFSQYPQYSCATTGSSLNAIA-DFYRNRTTPANVKFSLIERWASHKLLAKVFSE 192
G ++++ YPQYS +TT S+ +A+A DF + R P R+ +H F E
Sbjct: 134 GVRKLLVLPLYPQYSASTTASTFDALAKDFTKRRWLPEL-------RFITHYHDFSPFIE 186
Query: 193 RIKEKLDK-FDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELG-GRNPH 250
++++K +D R D L LF+ H +PL+ + GD Y E T E LG G++ +
Sbjct: 187 AAAQRIEKHWDAHGRADKL-LFSYHGIPLRYLKNGDPYHCECYKTSRLLAERLGLGKDEY 245
Query: 251 RLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIE 304
+QS+ G WLQPYTD +K +GVK + + F ++ +ET+ E+ E
Sbjct: 246 LTTFQSRFGREEWLQPYTDMTMKALPGKGVKSVQVFCPGFSSDCLETVEEIGEE 299
>UniRef50_Q5FSJ9 Cluster: Ferrochelatase; n=1; Gluconobacter
oxydans|Rep: Ferrochelatase - Gluconobacter oxydans
(Gluconobacter suboxydans)
Length = 343
Score = 103 bits (246), Expect = 8e-21
Identities = 82/299 (27%), Positives = 134/299 (44%), Gaps = 22/299 (7%)
Query: 21 KTAIVMLNMGGPETTD--QVGDYLHRIMTDRDMIQLPV---QSKLGPWIASRRTEEVKKK 75
+T I+++N+G P+ T V YL ++DR +I+ P Q L I ++R
Sbjct: 17 RTGILLINLGTPDDTGYFSVRRYLSEFLSDRRVIESPPLIWQPILQSIILTKRPFASGAN 76
Query: 76 YSEIG----GGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVE 131
Y+ I SP+ +T Q L + L + P + RY P A +
Sbjct: 77 YARIWHKEENASPLRVYTRRQAEGLAERLRA---DGVPVEW--GMRYGCPSVAKAVESLM 131
Query: 132 SDGADRVIIFSQYPQYSCATTGSSLNAI-ADFYRNRTTPANVKFSLIERWASHKLLAKVF 190
G DR+I + YPQYS TT ++ + + R R PA + + + H +
Sbjct: 132 DQGCDRIISIALYPQYSATTTATANDQLFRALMRLRRQPAVLT---VPSFPDHPAFIRAL 188
Query: 191 SERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELG-GRNP 249
+++ L K + I+ + H LP + +GDTY E T+S + LG
Sbjct: 189 ETSVQDTLAGLSFKPQQ---IVASFHGLPKTCIEKGDTYRDECERTISALRQALGLSEEQ 245
Query: 250 HRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDE 308
L +QS+ GPL W+QPYT +K QG+ + ++ F+ + +ETL E+ E +E
Sbjct: 246 MPLTFQSRFGPLEWVQPYTAPFVKALPAQGITKIAVIMPGFMVDCLETLDEIGNELREE 304
>UniRef50_Q03Z41 Cluster: Ferrochelatase; n=1; Leuconostoc
mesenteroides subsp. mesenteroides ATCC 8293|Rep:
Ferrochelatase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 315
Score = 102 bits (245), Expect = 1e-20
Identities = 77/296 (26%), Positives = 143/296 (48%), Gaps = 29/296 (9%)
Query: 21 KTAIVMLNMGGPETT--DQVGDYLHRIMTDRDMIQLPV---QSKLGPWIASRRTEEVKKK 75
K ++++N+G P++ D V YL ++D ++IQ+P Q L I +R+ + +
Sbjct: 3 KKGLLLVNLGTPDSPHPDDVKAYLKEFLSDTNVIQMPRLLWQPILRGKILPKRSFKSAEL 62
Query: 76 YSEIG--GGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESD 133
Y +I GSP++ + Q + + Q+ P A Y P + +E+
Sbjct: 63 YQKIWRKDGSPLMVYAKKQ----VEQVQQLQPNWIVR---CAMTYRKPNIAETLKEMRLA 115
Query: 134 GADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSER 193
GAD +++ +PQYS +T S ++ + R N+ ++++ + + + + +
Sbjct: 116 GADDIVVLPLFPQYSVTSTQSVIDQV------RKADKNI--NIVKSFYNDEAYLDLLARD 167
Query: 194 IKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRL- 252
I+E K D D LI+ + H +P V RGD Y +T +E +G P
Sbjct: 168 IREAWAKNDY----DRLII-SYHGVPESYVRRGDPYVDHCTATTQGVLERVGPLTPDNTH 222
Query: 253 -VWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCD 307
V+QS+ GP W++PY D ++ QG+K +++ AFV + +ET+ E+ +E D
Sbjct: 223 QVFQSRFGPTEWVKPYLSDTLRSLPSQGIKRVLVATPAFVADCLETIEEIHVENHD 278
>UniRef50_A5EXB1 Cluster: Ferrochelatase; n=1; Dichelobacter nodosus
VCS1703A|Rep: Ferrochelatase - Dichelobacter nodosus
(strain VCS1703A)
Length = 345
Score = 102 bits (245), Expect = 1e-20
Identities = 74/293 (25%), Positives = 139/293 (47%), Gaps = 22/293 (7%)
Query: 24 IVMLNMGGPETTDQVG--DYLHRIMTDRDMIQLPVQSKLGPW---IASRRTEEVKKKYSE 78
++++N+G P++++ + YL + ++D+ +I +P L I R + V K+Y
Sbjct: 13 VLLVNLGSPKSSNTIAVWQYLAQFLSDKRIIDIPRWRWLPILYGAILPLRAKRVAKRYRL 72
Query: 79 IG--GGSPILKWTNSQGSLLTQALDQMLPESAPHKHYV---AFRYVPPFTEDAFREVESD 133
I G+P++ T Q TQAL +L ++ H++ V A RY P A + +++
Sbjct: 73 IWTENGAPLVDITQQQ----TQALKILLAKTG-HQNIVVDYAMRYGVPSISSALQRLQAQ 127
Query: 134 GADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSER 193
++++ YPQY+ ATT S +A+A ++F + W HK +
Sbjct: 128 NVRQLLVIPMYPQYAEATTASVFDAVAAALEKTRALPEIRF--VHHWHDHKNYLDALAAA 185
Query: 194 IKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPH-RL 252
+ L K L+L + H +P ++ GD Y T + + H ++
Sbjct: 186 FQHYLSKNGAP----QLLLLSFHGVPKSVITEGDPYYDFCLETADLFAKRVHFPKEHIKV 241
Query: 253 VWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEY 305
++QS+ G PWL+PY D+ I K+G+ + ++ F + +ETL E+ + Y
Sbjct: 242 IFQSRFGRKPWLEPYADEIIADLPKRGITKIAVMCPGFSADCLETLDEIALRY 294
>UniRef50_Q8EBZ7 Cluster: Ferrochelatase 2; n=48;
Proteobacteria|Rep: Ferrochelatase 2 - Shewanella
oneidensis
Length = 327
Score = 102 bits (245), Expect = 1e-20
Identities = 79/296 (26%), Positives = 139/296 (46%), Gaps = 19/296 (6%)
Query: 15 GTAVKPKTAIVMLNMGGPE--TTDQVGDYLHRIMTDRDMIQLPV---QSKLGPWIASRRT 69
G A + K +++LN+G P+ T V YL ++D ++++P L + R
Sbjct: 2 GHAARGKVGVLLLNLGTPDAPTASAVRRYLAEFLSDPRVVEIPKLLWMLILYGIVLRVRP 61
Query: 70 EEVKKKYSEIG--GGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAF 127
+ Y ++ GSP++ + Q + L+ D++ + ++A RY P
Sbjct: 62 AKSAALYQKVWTEAGSPLMDISLRQTAKLS---DKLTADGHQVSVHLAMRYGNPSVASTL 118
Query: 128 REVESDGADRVIIFSQYPQYSCATTGSSLNAIA-DFYRNRTTPANVKFSLIERWASHKLL 186
RE+ G D++++ YPQY+ TTGS+ +AIA + + R P+ I + +
Sbjct: 119 REMHKQGIDKLVVLPLYPQYAAPTTGSAFDAIAKELSQWRYLPS---LHFINTYHDNPDF 175
Query: 187 AKVFSERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELG- 245
I+ D FD+ + L+L + H +P + + GD Y T E+LG
Sbjct: 176 IAALVNSIR---DDFDKHGKPQKLVL-SYHGMPERNLHLGDPYYCFCMKTTRLVAEQLGL 231
Query: 246 GRNPHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHEL 301
++ + +QS+ G WLQPYTD + QGV+ + +V AF + +ETL E+
Sbjct: 232 SKDEFAITFQSRFGKAKWLQPYTDATMAALPSQGVRDVAIVCPAFSADCLETLEEI 287
>UniRef50_Q2BIY0 Cluster: Ferrochelatase; n=2;
Gammaproteobacteria|Rep: Ferrochelatase - Neptuniibacter
caesariensis
Length = 336
Score = 101 bits (243), Expect = 2e-20
Identities = 81/291 (27%), Positives = 138/291 (47%), Gaps = 17/291 (5%)
Query: 21 KTAIVMLNMGGPETTDQ--VGDYLHRIMTDRDMIQ------LPVQSKLGPWIASRRTEEV 72
KTA+V++N+G P+ ++ V YL ++D +++ L S L I + R +V
Sbjct: 6 KTAVVLVNLGTPDKAEKGAVRRYLKEFLSDDRVVEGKGLRRLLWLSVLNGIILNVRPGKV 65
Query: 73 KKKYSEIGG-GSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVE 131
K Y+ I SP+ + Q S L L E +P + A Y P ++
Sbjct: 66 AKAYASIWEEDSPMRIILDKQVSELQLVLQSHHGEHSPDV-FAAMTYGKPGLTPLLHKLS 124
Query: 132 SDGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFS 191
G ++V++ YPQYS TT + +A F + +V+ ++ + H + +
Sbjct: 125 DTGYEKVLLIPMYPQYSATTTAPVYDQVAKFQLQQRRVLDVR--IVNSYYDHPKYVEALA 182
Query: 192 ERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHR 251
++ + +E + D LIL + H +P + +GD YP + T E+LG +
Sbjct: 183 NQVANFRAE-NESV--DKLIL-SYHGIPKEYADKGDPYPLQCHKTSELLAEKLGLADTEW 238
Query: 252 LV-WQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHEL 301
+ +QS+ GP WLQPYTD ++ +QGVK L + AF + +ETL E+
Sbjct: 239 MTTFQSRFGPAEWLQPYTDKTLEKLPEQGVKKLQIACPAFSADCLETLEEI 289
>UniRef50_Q62HD1 Cluster: Ferrochelatase; n=82; cellular
organisms|Rep: Ferrochelatase - Burkholderia mallei
(Pseudomonas mallei)
Length = 367
Score = 101 bits (242), Expect = 3e-20
Identities = 83/303 (27%), Positives = 141/303 (46%), Gaps = 26/303 (8%)
Query: 21 KTAIVMLNMGGPE--TTDQVGDYLHRIMTDRDMIQLPV---QSKLGPWIASRRTEEVKKK 75
+ A++++N+G P+ T V YL + ++D ++++P Q L I R KK
Sbjct: 28 RVAVLLVNLGTPDAPTPRAVRRYLAQFLSDPRVVEIPQLVWQVILCTLILPLRGRASAKK 87
Query: 76 YSEIG--GGSPILKWTNSQGSLLTQALDQMLPESAPHKHYV----AFRYVPPFTEDAFRE 129
Y+ + GSP+ +T Q ++ + P A + + V A RY P D +
Sbjct: 88 YAAVWLPEGSPLRVYTERQ-------VESVKPLFAANGYRVIVDYAMRYGTPSIADVLAQ 140
Query: 130 VESDGADRVIIFSQYPQYSCATTGSSLNA-IADFYRNRTTPANVKFSLIERWASHKLLAK 188
++ GA+RV++ YPQYS +TT ++ +A A R R P + + +A H
Sbjct: 141 LKRAGAERVLLLPMYPQYSSSTTATAFDAAFAALGRMRNQP---EVRTVRHYADHPAYIH 197
Query: 189 VFSERIKEKLDKFDEKIRD--DVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGG 246
+E++++ D D L+L + H +P + + GD Y + T + M LG
Sbjct: 198 ALAEQVRQYWAAHGRPAFDAGDKLVL-SFHGVPKRTLDLGDPYHDQCQQTAALLMSALGL 256
Query: 247 RNPH-RLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEY 305
R+ +QS+ G WLQPYT +K GV+ + F + +ET+ E+ IE
Sbjct: 257 TTFECRVTFQSRFGKAEWLQPYTAPTLKELGAAGVRRADVFCPGFTADCLETIEEIGIEV 316
Query: 306 CDE 308
DE
Sbjct: 317 RDE 319
>UniRef50_Q8IFR0 Cluster: Ferrochelatase; n=10; Plasmodium|Rep:
Ferrochelatase - Plasmodium falciparum
Length = 350
Score = 101 bits (241), Expect = 3e-20
Identities = 78/297 (26%), Positives = 145/297 (48%), Gaps = 20/297 (6%)
Query: 19 KPKTAIVMLNMGGPE--TTDQVGDYLHRIMTDRDMIQLPV---QSKLGPWIASRRTEEVK 73
K K I++ N+G PE T + YL +TD +++L L ++ R+ +V
Sbjct: 24 KSKIGILITNLGSPEKLTYWSLYKYLSEFLTDPRVVKLNRFLWLPILYTFVLPFRSGKVL 83
Query: 74 KKYSEIG--GGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAF--RYVPPFTEDAFRE 129
KY I GSP+ T++Q AL ++L E +K +++ RY +
Sbjct: 84 SKYKSIWIKDGSPLCVNTHNQ----CLALKKILNEKYNNKVVISYGMRYGERSIKKGLEY 139
Query: 130 VESDGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKV 189
++ + +++++ YPQ + T S+L+ I +N + ++F S L +
Sbjct: 140 LQKENINKLLVLPLYPQSAECTVSSTLDCIGKNLKNWSNVPELRF------ISGYCLKDI 193
Query: 190 FSERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELG-GRN 248
F +KE ++ + E ++ + HSLP++ V +GD YP + + ++ L ++
Sbjct: 194 FINTMKENIENYWELYGKSKKLIISYHSLPIRNVIQGDLYPFFCIESTKKLVKSLNLNKD 253
Query: 249 PHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEY 305
+ LV+QSK+ W++P +D I AKQG K + +V +F ++ +ETL E+ I Y
Sbjct: 254 DYILVFQSKIKGQQWVKPCIEDTIIRLAKQGYKQIDIVSPSFSSDCLETLEEIKIHY 310
>UniRef50_A3QC13 Cluster: Ferrochelatase; n=5;
Gammaproteobacteria|Rep: Ferrochelatase - Shewanella
loihica (strain BAA-1088 / PV-4)
Length = 355
Score = 100 bits (240), Expect = 4e-20
Identities = 82/302 (27%), Positives = 143/302 (47%), Gaps = 19/302 (6%)
Query: 15 GTAVKPKTAIVMLNMGGPE--TTDQVGDYLHRIMTDRDMIQLP--VQSKLGPWIASR-RT 69
G + KT ++++N+G P+ TT V YL ++D ++++P V + I R R
Sbjct: 30 GHGGRGKTTVLLMNLGTPDAPTTGAVRRYLAEFLSDPRVVEIPKLVWMLILHGIILRIRP 89
Query: 70 EEVKKKYSEIGG--GSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAF 127
+ Y I GSP++ T +Q L Q L + + RY P ++
Sbjct: 90 AKSAALYQSIWTEQGSPLMAITQAQRDKLAQKLSE---NGSDVNVDFCMRYGEPSVKETL 146
Query: 128 REVESDGADRVIIFSQYPQYSCATTGSSLNAIA-DFYRNRTTPANVKFSLIERWASHKLL 186
R + S+G D++I+ YPQY+ TT S+ +A+ + R P+ I + H
Sbjct: 147 RRLHSEGTDKLIVLPLYPQYAAPTTASAFDALTKELISWRYLPS---LHFINSYHDHPDY 203
Query: 187 AKVFSERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGG 246
++ I + F++ + L+L + H +P + ++ GD Y T +E LG
Sbjct: 204 IAALADSIAKD---FEQHGKPKKLVL-SYHGMPERNLNLGDPYYCLCQKTTRLVVERLGL 259
Query: 247 RNPHRLV-WQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEY 305
+ + +QS+ G WL PYTD +++ AK+GV + +V AF + +ETL E++ E
Sbjct: 260 TDDDYITTFQSRFGKAKWLGPYTDASLEALAKEGVDDVAIVCPAFSADCLETLEEIEHEN 319
Query: 306 CD 307
D
Sbjct: 320 RD 321
>UniRef50_Q8DFM2 Cluster: Ferrochelatase; n=16;
Gammaproteobacteria|Rep: Ferrochelatase - Vibrio
vulnificus
Length = 319
Score = 97.9 bits (233), Expect = 3e-19
Identities = 78/289 (26%), Positives = 135/289 (46%), Gaps = 22/289 (7%)
Query: 21 KTAIVMLNMGGPE--TTDQVGDYLHRIMTDR---DMIQLPVQSKLGPWIASRRTEEVKKK 75
K ++++N+G PE T V +L + + D+ DM + L I R+ +V K
Sbjct: 6 KRGVLLVNLGTPEEATAPAVKRFLSQFLHDQRVVDMTRWLWCPILHGIILPIRSPKVAKL 65
Query: 76 YSEIG--GGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESD 133
Y + GSP++ ++ Q L L+ P + + Y P D ++++
Sbjct: 66 YQTVWMKEGSPLMVYSKRQQVELQAKLN------CPVE--IGMTYGTPSVLDGVNKLQAQ 117
Query: 134 GADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSER 193
G D + + YPQYS TTG++ +A+A R +++F I + H L K +E
Sbjct: 118 GVDEICVLPLYPQYSGTTTGAAYDALAHALRKVAVVPSIQF--IRDYHDHPLYIKALAES 175
Query: 194 IKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELG-GRNPHRL 252
+++ + + + D L L + H +P + GD YP T ELG ++
Sbjct: 176 VRQS---WQVQGKGDYL-LCSYHGIPQRYADNGDVYPLHCEMTTELLRLELGLDKSQIGT 231
Query: 253 VWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHEL 301
+QS+ G WLQPYTD ++ +G+K L ++ AF + +ETL E+
Sbjct: 232 TYQSRFGREEWLQPYTDKTLESLPAKGIKSLDVITPAFSVDCLETLEEI 280
>UniRef50_Q6F7N0 Cluster: Ferrochelatase; n=5; Moraxellaceae|Rep:
Ferrochelatase - Acinetobacter sp. (strain ADP1)
Length = 340
Score = 97.5 bits (232), Expect = 4e-19
Identities = 70/294 (23%), Positives = 140/294 (47%), Gaps = 16/294 (5%)
Query: 19 KPKTAIVMLNMGGPE--TTDQVGDYLHRIMTDRDMIQLPV---QSKLGPWIASRRTEEVK 73
KPK +++ N+G P+ T V +L + ++D+ +I++P + L ++ R + V
Sbjct: 6 KPKVTVILANLGTPDVPTASAVRAFLKQFLSDQRVIEIPKLLWKIILYSFVLPFRPKRVA 65
Query: 74 KKYSEIGG-GSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVES 132
Y+ + G SP+ + +Q L + L P+ A Y P + +++ +
Sbjct: 66 HAYASVWGQDSPMREILFAQTDALKRQLISHYPQ-LDLNIVPAMTYGNPGVQHILKDLAA 124
Query: 133 DGADRVIIFSQYPQYSCATTGSSLNAIADFY-RNRTTPANVKFSLIERWASHKLLAKVFS 191
+ VI+ +PQYS +T +A A++ + R P ++I+ + H VF
Sbjct: 125 SPQEHVILLPLFPQYSATSTAPLYDAFANWIPKQRHLPG---LTIIKDYYRHP----VFI 177
Query: 192 ERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELG-GRNPH 250
+ + + +F ++ +L + H +P +GD Y T ++LG +
Sbjct: 178 QALVSSVQRFQQQHGKPQKLLMSFHGIPQPYADKGDPYADRCRETARLVAKQLGLTPDDW 237
Query: 251 RLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIE 304
+ +QS+ G W++PYTD+ + +A G+K + ++ AF + +ETL EL+I+
Sbjct: 238 AISFQSRFGKQEWVKPYTDELLTTWAANGIKSVQILSPAFSADCLETLEELEIQ 291
>UniRef50_A3TKF4 Cluster: Putative ferrochelatase; n=3;
Bacteria|Rep: Putative ferrochelatase - Janibacter sp.
HTCC2649
Length = 372
Score = 94.3 bits (224), Expect = 4e-18
Identities = 84/310 (27%), Positives = 133/310 (42%), Gaps = 36/310 (11%)
Query: 12 TASGTAVKPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEE 71
T A+ P A+++L+ GGPE D+V +L R+ RD + R EE
Sbjct: 4 TPDEDALAPYDAVLLLSFGGPEAPDEVVPFLRRVTAGRD-------------VPEERLEE 50
Query: 72 VKKKYSEIGGGSPILKWTNSQGSLLTQALD-QMLPESAPHKHYVAFRYVPPFTEDAFREV 130
V K Y GG SPI N Q L AL+ +++ + R PF D R
Sbjct: 51 VAKHYHHFGGVSPI----NGQNRELLAALEAELVRRGSAVPVLWGNRNSAPFVTDTLRAA 106
Query: 131 ESDGADR--VIIFSQYPQYS-CATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLA 187
+ G R V++ S Y YS C L A + ++ + +A H
Sbjct: 107 RAQGQLRICVVVTSAYSSYSGCRQYREDLAAATE--ELGLAAVDLDIDKVRPYALHPGFT 164
Query: 188 KVFSERIKEKLDKFDEKIRDDVLILFTAHSLPL-------KAVSRGDTYPHE---VASTV 237
V +E + + + D +LF HS+P S G+ Y + +
Sbjct: 165 AVNTEHLVDSVSTIDASKLPTTRLLFVTHSIPEAMDDTSGPGDSDGNLYVEQHLRAGYLI 224
Query: 238 SRTM-EELGGRNPHRLVWQSKVGP--LPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEH 294
++ + E G P LV+ S+ G PWL+P +D I+ A +GV ++L P+ FV++H
Sbjct: 225 AQGLTERTGVTLPQELVFCSRSGSPRTPWLEPDVNDRIEELAAEGVTTVVLAPIGFVSDH 284
Query: 295 IETLHELDIE 304
+E +++LD E
Sbjct: 285 MEVVNDLDRE 294
>UniRef50_A3U6F4 Cluster: Ferrochelatase; n=14; Bacteroidetes|Rep:
Ferrochelatase - Croceibacter atlanticus HTCC2559
Length = 354
Score = 93.9 bits (223), Expect = 5e-18
Identities = 88/333 (26%), Positives = 156/333 (46%), Gaps = 49/333 (14%)
Query: 24 IVMLNMGGPETTD--QVGDYLHRIMTDRDMIQLPVQSK---LGPWIASRRTEEVKKKYSE 78
++++N+G PE+TD V YL + D +I +P + + + + R ++ + YS+
Sbjct: 5 VLLVNLGSPESTDPKDVKKYLDEFLMDPRVIDVPYWFRAFLVKGIVLNTRPKKSAEAYSK 64
Query: 79 IGG--GSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGAD 136
I GSP++ +L++ L + + +A RY E A + + G +
Sbjct: 65 IWWEEGSPLI--------VLSERLQDKIQKQTEIPVDLAMRYGSMTIEKALKRLTDKGVN 116
Query: 137 RVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKE 196
+++ YPQ++ ATT ++ +A+ R P VK + + + + +V S IKE
Sbjct: 117 DILLVPLYPQFAMATT-ETIEVLAEKLRKEKFP-QVKLTSLAPFYNKPDYIEVLSRSIKE 174
Query: 197 KLDKFDEKIRDDVLILFTAHSLPLKAVSRGDT----------------------YPHEVA 234
KLD + +LF+ H +P + + + D Y H+
Sbjct: 175 KLDTTNYDH-----LLFSYHGVPERHIRKSDITNSHCQIDGSCCKAQSDAHRFCYRHQCY 229
Query: 235 STVSRTMEELGGR-NPHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNE 293
T EELG + +QS++G PWLQPYTD I+ K+G+K++ +V AFV++
Sbjct: 230 ETTRLVGEELGLKPGTFSTSFQSRLGFDPWLQPYTDRTIERMGKEGIKNMAIVTPAFVSD 289
Query: 294 HIETLHELDIE----YCDEVAKELRTISELSAR 322
+ETL E+ +E + + KE TI L+ R
Sbjct: 290 CLETLEEIAMEGEEIFHEVGGKEFTTIPCLNDR 322
>UniRef50_Q82KJ6 Cluster: Ferrochelatase; n=10; Actinobacteria
(class)|Rep: Ferrochelatase - Streptomyces avermitilis
Length = 375
Score = 92.7 bits (220), Expect = 1e-17
Identities = 86/305 (28%), Positives = 135/305 (44%), Gaps = 39/305 (12%)
Query: 20 PKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVKKKYSEI 79
P A+++L+ GGPE D V +L + R I R +EV + Y
Sbjct: 9 PYDALLLLSFGGPEGPDDVVPFLENVTRGRG-------------IPRERLKEVGQHYFLF 55
Query: 80 GGGSPILKWTNSQGSLLTQALDQMLPESAPHKH-YVAFRYVPPFTEDAFREVESDGADRV 138
GG SPI N Q L AL + E + Y R P+ D RE+ +DG R+
Sbjct: 56 GGISPI----NDQNRALLDALRKDFAEHGLNLPVYWGNRNWAPYLTDTLREMAADGRRRI 111
Query: 139 IIF--SQYPQYS-CATTGSSL-NAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERI 194
++ S Y YS C +L A+A V + + +H + +E +
Sbjct: 112 LVLATSAYASYSGCRQYRENLAGALATLEAEGLEVPRV--DKLRHYFNHPGFVEPMTEGV 169
Query: 195 KEKLDKFDEKIRDDVLILFTAHSLPLKAV-SRGDTYPH-----------EVASTVSRTM- 241
L + E +R I FT HS+P A + G H +VA ++ +
Sbjct: 170 LRSLAELPEDVRPGAHIAFTTHSIPTAAADTSGPVEEHGDGGAYVKQHLDVARLIADAVR 229
Query: 242 EELGGRNPHRLVWQSKVGP--LPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLH 299
EE G +P +LV+QS+ G +PWL+P D ++ GV +++ P+ FV++H+E L+
Sbjct: 230 EETGIDHPWQLVYQSRSGAPHIPWLEPDICDHLQELHGAGVPAVVMAPIGFVSDHMEVLY 289
Query: 300 ELDIE 304
+LD E
Sbjct: 290 DLDTE 294
>UniRef50_Q1ITV1 Cluster: Ferrochelatase; n=2; Acidobacteria|Rep:
Ferrochelatase - Acidobacteria bacterium (strain
Ellin345)
Length = 303
Score = 92.3 bits (219), Expect = 2e-17
Identities = 54/201 (26%), Positives = 97/201 (48%), Gaps = 8/201 (3%)
Query: 113 YVAFRYVPPFTEDAFREVESDGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANV 172
Y+ R PF D +++ DG + + PQ S + G A+ + + P V
Sbjct: 73 YIGMRNWHPFVADTIEQMKQDGIEHCVALCLAPQNSRTSVGLYRKALME----KNPPFTV 128
Query: 173 KFSLIERWASHKLLAKVFSERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHE 232
F +E W H LL + F+E + +K + D+ +FTAHS+P + ++ GD Y +
Sbjct: 129 DF--VESWHDHPLLIQAFAENHRAGYEKARAEASHDLPRIFTAHSVPERTITEGDPYEAQ 186
Query: 233 VASTVSRTMEELGGRNP-HRLVWQSK-VGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAF 290
T + + LG ++ R +QS+ + W P + ++ AK+G + + P+ F
Sbjct: 187 TRETAALVAKGLGLKDAVWRFAFQSQGMSGGTWRGPTVESTLEGLAKEGHRGVFFQPIGF 246
Query: 291 VNEHIETLHELDIEYCDEVAK 311
V +H+E L+++DI + D K
Sbjct: 247 VCDHVEVLYDIDIGFRDFAEK 267
>UniRef50_Q5P1H1 Cluster: Ferrochelatase; n=3;
Betaproteobacteria|Rep: Ferrochelatase - Azoarcus sp.
(strain EbN1) (Aromatoleum aromaticum (strain EbN1))
Length = 365
Score = 91.9 bits (218), Expect = 2e-17
Identities = 71/293 (24%), Positives = 133/293 (45%), Gaps = 18/293 (6%)
Query: 21 KTAIVMLNMGGPE--TTDQVGDYLHRIMTDRDMIQLPVQ---SKLGPWIASRRTEEVKKK 75
+T I+++N+G P T V YL ++D ++++P L I + R ++ +K
Sbjct: 17 RTGILLVNLGTPAAPTAAAVRPYLKEFLSDPRVVEIPRAIWWPILNGVILNLRPKKSAEK 76
Query: 76 YSEI--GGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESD 133
Y+ I GSP+ T Q LL L S A RY P D ++++
Sbjct: 77 YAAIWSDAGSPLKVHTERQAKLLAGYLGHAGVTSVVVDW--AMRYGAPSISDILGRMKAE 134
Query: 134 GADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSER 193
G R+++ YPQY+ +TT S ++ +A +++ + + H +
Sbjct: 135 GCSRILVVPLYPQYAASTTASVIDEVAGCLTRWRNLPEIRY--VRNFHDHPGYVGALARS 192
Query: 194 IKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHR-- 251
+++ K E D +++ F H +P +++ GD Y H +R + P R
Sbjct: 193 VRDHWAKHGEP--DQLVMSF--HGIPKRSLDLGDPY-HCECHVTARLLAAKLDLPPERWQ 247
Query: 252 LVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIE 304
L +QS+ G WL+PYT ++ ++G + ++ F ++ +ETL E+ +E
Sbjct: 248 LTFQSRFGKAEWLKPYTQPTLEALGRKGTGRVDVICPGFASDCLETLEEIALE 300
>UniRef50_Q1ZEV1 Cluster: Ferrochelatase; n=1; Psychromonas sp.
CNPT3|Rep: Ferrochelatase - Psychromonas sp. CNPT3
Length = 325
Score = 91.9 bits (218), Expect = 2e-17
Identities = 72/292 (24%), Positives = 131/292 (44%), Gaps = 19/292 (6%)
Query: 21 KTAIVMLNMGGPE--TTDQVGDYLHRIMTDRDMIQLPVQSKLGPW---IASRRTEEVKKK 75
K A++++N+G PE TT V +L + D+ ++ +P L I R V K
Sbjct: 10 KRAVLLVNLGTPEQATTKSVRAFLKSFLLDKRVVDMPRLFWLPILYLVILPFRAPRVSKL 69
Query: 76 YSEIGG--GSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESD 133
Y +I GSP+ + S + AL E K +A Y P + +++ +
Sbjct: 70 YQKIWEKKGSPLRILSESLNEKVALAL-----EKDNVKCVLAMTYGAPSIANTLQKLSDE 124
Query: 134 GADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSER 193
G + I YPQYS +TT + + F + + + F + H L +
Sbjct: 125 GITELTIIPLYPQYSVSTTAPVFDQVGRFIKGQINFPGITFK--NNYHDHPLYIDALCQS 182
Query: 194 IKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLV 253
I+ + ++F+ H +P + V +GD Y + +V+ +++LG + L+
Sbjct: 183 IQAHWLNHGRAEK----LIFSFHGIPQRYVEKGDPYQWQCEQSVALVVKQLGLNSQDYLI 238
Query: 254 -WQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIE 304
+QS++G WL PY D +K A +G + ++ AF + +ETL E+ ++
Sbjct: 239 AYQSRMGREAWLMPYVDLELKSMANEGCSSVDIICPAFATDCLETLEEMAMQ 290
>UniRef50_Q3AEU4 Cluster: Ferrochelatase; n=1; Carboxydothermus
hydrogenoformans Z-2901|Rep: Ferrochelatase -
Carboxydothermus hydrogenoformans (strain Z-2901 / DSM
6008)
Length = 292
Score = 91.5 bits (217), Expect = 3e-17
Identities = 83/284 (29%), Positives = 128/284 (45%), Gaps = 31/284 (10%)
Query: 23 AIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVKKKYSEIGGG 82
A+V++ G P+ + +G ++ RIM + P + + V+ +Y +IGG
Sbjct: 3 AVVLVAFGCPDCLENIGPFMERIMG-----RTPPPALIAA---------VRSRYEKIGGK 48
Query: 83 SPILKWTNSQGSLLTQAL-DQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRVIIF 141
SP+ + T+ Q L L + L + A Y +R P E F V+ GA +
Sbjct: 49 SPLTEITSQQARALKTLLGSEFLVDFA----YQYWR--PEIPEVVFNLVQK-GAKTIYFL 101
Query: 142 SQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKLDKF 201
S +TG+ I + P +KF A + + + L F
Sbjct: 102 PMSAFNSQVSTGAYQKTIKNL--EEKFP-EIKFYFKGGLAEEPYFIEAHRQLLTTALQPF 158
Query: 202 DEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQSK-VGP 260
K + I+FTAH+LP KA+ +GD Y E TV P R +QSK
Sbjct: 159 SPK---NTGIIFTAHNLPKKAIEQGDPYFAEFLKTVEAIARTFPF--PWRYAFQSKGKSG 213
Query: 261 LPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIE 304
WL+P DD I + QGV+++I+ P+ FV +HIETL++LDIE
Sbjct: 214 EEWLKPEVDDVIISWQNQGVENIIINPIGFVADHIETLYDLDIE 257
>UniRef50_Q98H61 Cluster: Ferrochelatase; n=31;
Alphaproteobacteria|Rep: Ferrochelatase - Rhizobium loti
(Mesorhizobium loti)
Length = 353
Score = 91.1 bits (216), Expect = 4e-17
Identities = 78/309 (25%), Positives = 134/309 (43%), Gaps = 21/309 (6%)
Query: 7 PPAFSTASGTAVKPKTAIVMLNMGGPETTD--QVGDYLHRIMTDRDMIQLPVQ---SKLG 61
P + A K ++++N+G P+ T+ + YL ++D +I+L L
Sbjct: 14 PVGVTAGHAPAGAGKVGVLLVNLGTPDGTEFKPMWRYLREFLSDPRVIELNKAIWYPILY 73
Query: 62 PWIASRRTEEVKKKYSEIGGG----SPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFR 117
+ + R ++ Y+ I SP+ +T +Q L +AL LP+ A R
Sbjct: 74 GLVLTTRPKKSGANYARIWNQERNESPLRTYTRAQSEKLAEALGD-LPDVTVDW---AMR 129
Query: 118 YVPPFTEDAFREVESDGADRVIIFSQYPQYSCATTGSSLNAI-ADFYRNRTTPANVKFSL 176
Y P T + + G DR++ F YPQYS TT ++ + + + R PA
Sbjct: 130 YGNPSTASVAERLVAQGCDRILSFPLYPQYSATTTATANDQLFRALMKLRRAPA---IRS 186
Query: 177 IERWASHKLLAKVFSERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVAST 236
+ + + + + + I+ L D + +++ + H +P +GD Y T
Sbjct: 187 VPPYYAEPVYIEALASSIERHLATLDF---EPEVVITSYHGIPKPYSDKGDPYQAHCLET 243
Query: 237 VSRTMEELGGRNPHRLV-WQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHI 295
E+LG + +QS+ G WLQPYTD ++ K GVK + +V F + I
Sbjct: 244 TRLLREKLGWDEKKLITTFQSRFGAQEWLQPYTDKTVEKLGKDGVKSIAIVNPGFSVDCI 303
Query: 296 ETLHELDIE 304
ETL E+ E
Sbjct: 304 ETLDEIGRE 312
>UniRef50_Q9Z7V1 Cluster: Ferrochelatase; n=12; Chlamydiaceae|Rep:
Ferrochelatase - Chlamydia pneumoniae (Chlamydophila
pneumoniae)
Length = 327
Score = 91.1 bits (216), Expect = 4e-17
Identities = 74/287 (25%), Positives = 132/287 (45%), Gaps = 21/287 (7%)
Query: 23 AIVMLNMGGPETTDQVGDYLHRIMTDRDMIQ--LP--VQSKLGPWIASRRTEEVKKKYSE 78
A ++ N GGP + ++L ++TDRD+ LP + L +IA +R +V +Y
Sbjct: 5 AYLLANFGGPRHAKDLQEFLISLLTDRDVTGTFLPRVLHRHLFTFIAKKRVPKVLPQYQS 64
Query: 79 IGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRV 138
+ SPI T + L + L ++L H RY+P E + + V
Sbjct: 65 LQNWSPIYFDTET----LAKTLSEILRAPVIPFH----RYLPSTHEKTLLALRTLHTRHV 116
Query: 139 IIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKL 198
I +P ++ + TGS I F+ + S I ++ S + + I++ L
Sbjct: 117 IGIPLFPHFTYSVTGS----IVRFFMKHVP--EIPISWIPQFGSDSKFVSLITCHIRDFL 170
Query: 199 DKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQSKV 258
K + + LF+ H LP++ +S+GD Y + + S ++ + L +QSK
Sbjct: 171 QKLGI-LEKECCFLFSVHGLPVRYISQGDPYSKQCYESFSAITTNFK-QSENFLCFQSKF 228
Query: 259 GPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEY 305
GP WL P T + ++I+VP F+++H+ETL+E++ +Y
Sbjct: 229 GPGKWLSPSTAQLCQ-NIDTDKPNVIVVPFGFISDHLETLYEIERDY 274
>UniRef50_A1K8P4 Cluster: Ferrochelatase; n=3;
Betaproteobacteria|Rep: Ferrochelatase - Azoarcus sp.
(strain BH72)
Length = 363
Score = 90.6 bits (215), Expect = 5e-17
Identities = 73/293 (24%), Positives = 132/293 (45%), Gaps = 20/293 (6%)
Query: 21 KTAIVMLNMGGP--ETTDQVGDYLHRIMTDRDMIQLPVQ---SKLGPWIASRRTEEVKKK 75
+T I+++N+G P T + YL + ++D ++++P L I + R + K
Sbjct: 17 RTGILLVNLGTPVAPTAAALRPYLQQFLSDPRVVEIPRAVWLPLLNGVILNTRPRKSAAK 76
Query: 76 YSEI--GGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESD 133
Y+ I GSP+ T Q L+ A RY P D + +
Sbjct: 77 YASIWTDEGSPLAVHTRRQAELIAARFASRDDVRVDW----AMRYGAPAVADKLGALRAA 132
Query: 134 GADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSER 193
G R+++ YPQY+ +TT S ++ +A ++ ++F + + +
Sbjct: 133 GCTRILVVPMYPQYAASTTASVMDEVARCLQHWRNLPELRF--VRSFHDDPGYIGALAAS 190
Query: 194 IKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLV 253
++E + + R +L + H LP + RGD Y E T +R + E G P R++
Sbjct: 191 VREHWTRHGQPDR----LLMSFHGLPRYTLERGDPYHCECHRT-ARLLAESLGLAPERVI 245
Query: 254 --WQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIE 304
+QS+ G WL+PYT ++ A+ GV + ++ FV + +ETL E+ +E
Sbjct: 246 VSFQSRFGRTRWLEPYTQPTLEALARDGVGRVDVMCPGFVADCLETLEEIAME 298
>UniRef50_Q72L32 Cluster: Ferrochelatase; n=2; Thermus
thermophilus|Rep: Ferrochelatase - Thermus thermophilus
(strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 317
Score = 90.2 bits (214), Expect = 6e-17
Identities = 56/212 (26%), Positives = 97/212 (45%), Gaps = 8/212 (3%)
Query: 105 PESAPH---KHYVAFRYVPPFTEDAFREVESDGADRVIIFSQYPQYSCATTGSSLNAIAD 161
P APH + YV ++ P +A + DG R + P YS + +
Sbjct: 81 PPRAPHGPARVYVGTKHWHPSIGEAVAAMHEDGVRRAVAIVAAPHYSLRSVAEYREKVDS 140
Query: 162 FYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKLDKFDEKIRDDVLILFTAHSLPLK 221
+ T P + F +E + +H L ++ R++E + + K +FTAHS+PL
Sbjct: 141 ALK--TLPEPIDFVWVESYEAHPGLIAAYARRLEEVIWRL--KNPGKAAYVFTAHSIPLS 196
Query: 222 AVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVK 281
AV +GD YP +V T ++L H + P PWL P ++ ++ ++G +
Sbjct: 197 AVEKGDPYPRQVEKTAELIAKKLALPRFHVAYQSAGRTPEPWLGPDINELLRTLKEEGYE 256
Query: 282 HLILVPVAFVNEHIETLHELDIEYCDEVAKEL 313
+ + V F +H+E ++LD+E A+EL
Sbjct: 257 EVAVQAVGFPADHLEVFYDLDLE-AQATAREL 287
>UniRef50_Q28VQ2 Cluster: Ferrochelatase; n=9; Rhodobacteraceae|Rep:
Ferrochelatase - Jannaschia sp. (strain CCS1)
Length = 370
Score = 89.8 bits (213), Expect = 8e-17
Identities = 75/295 (25%), Positives = 135/295 (45%), Gaps = 19/295 (6%)
Query: 21 KTAIVMLNMGGPETTD--QVGDYLHRIMTDRDMIQLPV---QSKLGPWIASRRTEEVKKK 75
K +++ N+G P+ D + YL+ ++D+ +I Q L I S+R
Sbjct: 42 KVGVLLANLGTPDNYDYWSMRRYLNEFLSDKRVIDYSPWIWQPLLQLVILSKRPFSSGAA 101
Query: 76 YSEI----GGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVE 131
Y I G SP+ T Q + + + + + RY P T+ E+
Sbjct: 102 YKSIWNHEAGESPLATITKDQTAKMKALMADRYGDDVVVDY--CMRYGNPSTKSKVDELV 159
Query: 132 SDGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFS 191
+ G +++ F YPQY+ AT+ ++ + N V+ +E + ++ L +
Sbjct: 160 AQGCTKILFFPLYPQYAGATSATACDQFFRSLENIKWQPQVR--TVEPYYANPLYIDALA 217
Query: 192 ERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHR 251
+ I+ D ++ D+L+ + H +P + + GD Y H SR ++E G + +
Sbjct: 218 QSIERAYAAMD--VKPDLLVT-SYHGVPKRYLMEGDPY-HCQCQKTSRLLKERLGWDDTQ 273
Query: 252 LV--WQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIE 304
+V +QSK GP WLQPYT + + A++G K + + AF + IETL E++ E
Sbjct: 274 IVTTFQSKFGPEEWLQPYTVEEVARLAEKGKKRIAVCAPAFSADCIETLEEINEE 328
>UniRef50_Q9PFU1 Cluster: Ferrochelatase; n=13;
Xanthomonadaceae|Rep: Ferrochelatase - Xylella
fastidiosa
Length = 320
Score = 89.0 bits (211), Expect = 1e-16
Identities = 76/297 (25%), Positives = 133/297 (44%), Gaps = 22/297 (7%)
Query: 22 TAIVMLNMGGPE--TTDQVGDYLHRIMTDRDMIQLPV---QSKLGPWIASRRTEEVKKKY 76
TA++++N+G PE T V YL ++DR ++ +P + L I R KY
Sbjct: 7 TALLIVNLGTPEAPTAAAVRRYLGEFLSDRRVVSIPPLFWKPLLHMVILPIRGPRSASKY 66
Query: 77 SEIG--GGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDG 134
+++ GSP+ +T + + L Q LP+ + A RY P A +++
Sbjct: 67 AKVWLQEGSPLSVYTRR----IAEGLTQHLPD---WRVAWAMRYGAPALTKALDALQAQQ 119
Query: 135 ADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERI 194
R++I YPQYS TT +S+ + + + RT V+ I+ +A + I
Sbjct: 120 VRRIVILPLYPQYSTTTT-ASVQDVVEAWCKRTPQVQVE--CIQDYAEDSAWVAAVAASI 176
Query: 195 KEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELG-GRNPHRLV 253
+ + ++F+ H LP + + GD YP + S L + L
Sbjct: 177 RRHWQAHGRSEK----LMFSFHGLPQRVANNGDPYPQRCQVSASLIAAALDLNESEWVLG 232
Query: 254 WQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVA 310
+QS+ G WLQPY + + A+ G++ LV F + +ETL E+ + + + +A
Sbjct: 233 YQSRFGAERWLQPYAEPTLWALAESGIRRFDLVCPGFSVDCLETLEEVALGFSETLA 289
>UniRef50_Q9K097 Cluster: Ferrochelatase; n=5; Neisseria|Rep:
Ferrochelatase - Neisseria meningitidis serogroup B
Length = 336
Score = 89.0 bits (211), Expect = 1e-16
Identities = 75/289 (25%), Positives = 133/289 (46%), Gaps = 21/289 (7%)
Query: 21 KTAIVMLNMGGPE--TTDQVGDYLHRIMTDRDMIQLPV---QSKLGPWIASRRTEEVKKK 75
+TA+++LN+G P+ T V YL +TDR +++LP L + + R ++
Sbjct: 17 RTAVLLLNLGTPDAPTAQAVRPYLKSFLTDRRVVELPKWLWYPILHGLVLTLRPKKSAHA 76
Query: 76 YSEIG--GGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESD 133
Y +I GSP+ +T Q + L + + ++ +H A Y P D E+++
Sbjct: 77 YEKIWFKEGSPLEVYTARQAAALAKRMPDLIV-----RH--AMTYGNPSVADVLSELKAQ 129
Query: 134 GADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSER 193
GA R+++ YPQY+ +++G++++ + + + +V+ + R+
Sbjct: 130 GAGRLLVIPMYPQYAASSSGAAVDKVCEQLLLQRNQMSVR--TVSRFYDDTGYIDAMKNH 187
Query: 194 IKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLV 253
I L + E R L+L + H +P K GD YP E T E L +V
Sbjct: 188 I---LRYWAEHGRGKKLML-SFHGVPQKHHDLGDPYPDECRHTAKLLAEALELTEDQYVV 243
Query: 254 -WQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHEL 301
+QS+ G W+ P T D KQGV L + F+ + +ET+ E+
Sbjct: 244 SFQSQFGRAKWVTPSTQDLFGKLPKQGVTELDVFCPGFLADCLETMEEI 292
>UniRef50_Q97R30 Cluster: Ferrochelatase; n=18; Streptococcus|Rep:
Ferrochelatase - Streptococcus pneumoniae
Length = 364
Score = 88.6 bits (210), Expect = 2e-16
Identities = 62/235 (26%), Positives = 118/235 (50%), Gaps = 22/235 (9%)
Query: 81 GGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRVII 140
GG+P+ K T + +L+ L + + Y A ++ PF D ++E+DG ++ I
Sbjct: 50 GGTPLQKITRQEVALVEARL------GSEYSVYFANKFSSPFIPDVIGQMEADGIEQCIC 103
Query: 141 FSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKLDK 200
P YS S+ F ++ ++F +I+ W + L +++ I + L
Sbjct: 104 LILEPHYSFY----SVMGYEKFLESK----QIQFLVIKDWYQEEALLNYWADEIAKILK- 154
Query: 201 FDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELG-GRNPHRLVWQSK-- 257
+E +D ++F+AHS+P+ A+ GD Y ++ E+LG + WQS+
Sbjct: 155 -EEVKQDSFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESD 213
Query: 258 VGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVAKE 312
+G +PW++P + ++ + H I VP++F++EHIE L + D+E C ++ +E
Sbjct: 214 IG-IPWIKPDVLEYLREQTEHP-DHYIFVPISFISEHIEVLFDNDVE-CYDLCQE 265
>UniRef50_Q5DEU6 Cluster: SJCHGC05531 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC05531 protein - Schistosoma
japonicum (Blood fluke)
Length = 152
Score = 88.2 bits (209), Expect = 3e-16
Identities = 38/72 (52%), Positives = 52/72 (72%)
Query: 241 MEELGGRNPHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHE 300
M++L P+RL WQSKVGP WL P T D++ ++ G +H IL+PVAF +HIETL+E
Sbjct: 1 MKQLNFSWPYRLTWQSKVGPAAWLGPSTADSLYGLSRLGYRHAILIPVAFTLDHIETLYE 60
Query: 301 LDIEYCDEVAKE 312
+D+EYC EVA +
Sbjct: 61 MDVEYCTEVASK 72
>UniRef50_Q8XW32 Cluster: Ferrochelatase; n=17; Proteobacteria|Rep:
Ferrochelatase - Ralstonia solanacearum (Pseudomonas
solanacearum)
Length = 371
Score = 87.8 bits (208), Expect = 3e-16
Identities = 74/300 (24%), Positives = 134/300 (44%), Gaps = 24/300 (8%)
Query: 21 KTAIVMLNMGGPETTD--QVGDYLHRIMTDRDMIQLPVQSK---LGPWIASRRTEEVKKK 75
+TAI+++N+G P+ T +VG YL + ++D ++++P + L I R+ K
Sbjct: 16 RTAILLVNLGTPDGTSPREVGRYLRQFLSDPRVVEIPRAAWWFILNVLILPLRSRASAHK 75
Query: 76 YSEIG------GGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFRE 129
Y + GSP+L ++ Q L Q LD + A RY P +
Sbjct: 76 YETVWLREANMTGSPLLVYSERQAHALQQLLDAQGHDVVVA---CAMRYGNPSIPSVMQT 132
Query: 130 VESDGADRVIIFSQYPQYSCATTGSSLNAIADFY-RNRTTPANVKFSLIERWASHKLLAK 188
+ G +R+++ YPQYS TT ++ + + + R P + L++ + H
Sbjct: 133 LRKQGVERILVLPMYPQYSGTTTATAFDEVFRVMGQMRNQP---ELRLVKHFHDHPAYIN 189
Query: 189 VFSERIKEKLDKF--DEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGG 246
+++ + + R D L+L + H +P + + GD Y H R + E G
Sbjct: 190 ALHQQVGAYWAQHGAPDFARGDKLLL-SFHGVPRRTLELGDPY-HCACLKTGRLLGEALG 247
Query: 247 RNP--HRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIE 304
P + + +QS+ G WLQPYT ++ + G + + F + +ETL E+ +E
Sbjct: 248 LQPGQYLVTFQSRFGRAEWLQPYTAPTLEELGRVGTGRVDVFCPGFPADCLETLEEIAME 307
>UniRef50_Q82UK8 Cluster: Ferrochelatase; n=2;
Betaproteobacteria|Rep: Ferrochelatase - Nitrosomonas
europaea
Length = 364
Score = 87.0 bits (206), Expect = 6e-16
Identities = 69/292 (23%), Positives = 136/292 (46%), Gaps = 16/292 (5%)
Query: 21 KTAIVMLNMGGPE--TTDQVGDYLHRIMTDRDMIQLPVQSK---LGPWIASRRTEEVKKK 75
K ++M+N+G P+ T + YL + +++ +++ P L I + R + KK
Sbjct: 17 KIGVLMINLGTPDAPTAKALRAYLKQFLSEPRIVEFPRWLWWFILNGIILNVRPAKSAKK 76
Query: 76 YSEI--GGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESD 133
Y +I GSP+ T Q +L+ L+Q S ++ A P + ++++
Sbjct: 77 YEQIWTSEGSPLRVHTARQTALVAALLEQQADSSLVVEY--AMIIGNPSIAEKLQQMKVQ 134
Query: 134 GADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSER 193
G DR+++ +PQY+ ++TG L+ + R +++ + + ++
Sbjct: 135 GCDRILVLPLFPQYAASSTGCVLDGVFSELRKMRNIPDIR--TVRHYHDDPGYIAALAQN 192
Query: 194 IKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELG-GRNPHRL 252
+++ +K + D ++I F H +P K + GD Y E T E L + +++
Sbjct: 193 VRDYWEKHGQP--DKLIISF--HGVPRKTLEMGDPYHCECQKTGRLLAEALELADDRYQI 248
Query: 253 VWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIE 304
+QS+ G WL PYT + + KQ + +V FV++ +ETL E+ +E
Sbjct: 249 CFQSRFGFAQWLGPYTAEILAELGKQKTGRVDVVCPGFVSDCLETLEEIALE 300
>UniRef50_Q6MAW8 Cluster: Ferrochelatase; n=5; Bacteria|Rep:
Ferrochelatase - Protochlamydia amoebophila (strain
UWE25)
Length = 347
Score = 85.4 bits (202), Expect = 2e-15
Identities = 88/317 (27%), Positives = 140/317 (44%), Gaps = 44/317 (13%)
Query: 21 KTAIVMLNMGGPETT--DQVGDYLHRIMTDRDMIQLPV---QSKLGPWIASRRTEEVKKK 75
+T I+++N+G P+T V YL+ +TD +I LP Q + I R ++
Sbjct: 4 RTGILLVNLGTPKTPRPKDVYRYLNEFLTDGRVIDLPWLKRQLLVRCIIVPFRYKQSSML 63
Query: 76 YSEI--GGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESD 133
Y ++ GSP+L G + L +L ES + +A RY P E+ ++
Sbjct: 64 YQKLWTAEGSPLLV----HGIAVQTKLQMILGESFQVE--LAMRYQNPSIEEGLERLKLA 117
Query: 134 GADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSER 193
++IF +PQY+ ATTGS + + + F I + H L F ER
Sbjct: 118 NVKEIVIFPLFPQYASATTGSVHQEVMKHLQQWQNIPTLTF--INSYPDHPGLVGAFCER 175
Query: 194 IKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDT--------------------YPHEV 233
K+ +D I D LF+ H LP + + +GD+ Y +
Sbjct: 176 AKQ----YDLSIYD--YFLFSFHGLPERQIRKGDSTGKCLTENCCQVICSDNAFCYKAQC 229
Query: 234 ASTVSRTMEELGGR-NPHRLVWQSKVGPLPWLQPYTDDAIK-LYAKQGVKHLILVPVAFV 291
T +L + + + +QS++G W+QPYT D +K AK K L+ P AFV
Sbjct: 230 YRTAKAIASKLRIKLEQYTVCFQSRLGKETWIQPYTSDLLKDCLAKNRKKILVFCP-AFV 288
Query: 292 NEHIETLHELDIEYCDE 308
+ +ET E+ IEY +E
Sbjct: 289 CDCLETTCEVSIEYAEE 305
>UniRef50_Q6MHT3 Cluster: Ferrochelatase; n=1; Bdellovibrio
bacteriovorus|Rep: Ferrochelatase - Bdellovibrio
bacteriovorus
Length = 335
Score = 85.4 bits (202), Expect = 2e-15
Identities = 76/303 (25%), Positives = 139/303 (45%), Gaps = 27/303 (8%)
Query: 21 KTAIVMLNMGGPET--TDQVGDYLHRIMTDRDMIQLPVQSK---LGPWIASRRTEEVKKK 75
K ++++N+G P++ + V YL + D D+I LP + + I RR +
Sbjct: 3 KKGLLLINIGSPKSYQVNDVKKYLSEFLMDEDVITLPYVLRWPLVNLLIVPRRAPFSAEN 62
Query: 76 YSEIG--GGSPILKWTNSQGSLLTQAL-DQMLPESAPHKHYVAFRYVPPFTEDAFREVES 132
Y ++ GSPI +T +LL + L DQ + + V +Y P E A ++++
Sbjct: 63 YKKVWMKEGSPIAVYTRRFAALLQEELKDQFVVK-------VGLQYSEPSVESALKDLQQ 115
Query: 133 DGADRVIIFSQYPQYSCATTGSSLNAIADFYR--NRTTPANVKFSLIERWASHKLLAKVF 190
G D +++ +PQY+ AT GSS + + T P + + + K+
Sbjct: 116 AGVDEILVAPMFPQYAEATNGSSFKLAERMAKKLHLTAPLRRLPAFFDDASFVGTSVKLV 175
Query: 191 SERIKEK-LDKF--------DEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTM 241
E +++K +D + + +R L T K + Y + +T +
Sbjct: 176 EETLQDKEVDHYLFSFHGLPESHVRKIPGCLTTEDCCFEKNACAKNCYRAQCFATATAIA 235
Query: 242 EELGGRNPH-RLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHE 300
E L H + +QS++G WL+P TD ++++ AK G K++ ++ +FV + IETL E
Sbjct: 236 ESLNLAPSHWSVAFQSRLGRAEWLKPATDHSLEVLAKTGKKNIAVICPSFVADCIETLEE 295
Query: 301 LDI 303
+ I
Sbjct: 296 IGI 298
>UniRef50_Q8D226 Cluster: Ferrochelatase; n=1; Wigglesworthia
glossinidia endosymbiont of Glossina brevipalpis|Rep:
Ferrochelatase - Wigglesworthia glossinidia brevipalpis
Length = 321
Score = 84.6 bits (200), Expect = 3e-15
Identities = 74/295 (25%), Positives = 136/295 (46%), Gaps = 20/295 (6%)
Query: 18 VKPKTAIVMLNMGGPETTDQ--VGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVK-K 74
+K I++ N+G P ++ V YL ++D+ +I + S+ WI + K
Sbjct: 1 MKNNIGIIISNVGTPSHPNKKSVKKYLSEFLSDKRVIDI---SRFF-WIPYLHLYFLPLK 56
Query: 75 KYSEIGGGSPILKWTNSQGSLLTQALDQM--LPESAPH-KHYVAFRYVPPFTEDAFRE-V 130
Y + I W L+ +L+Q L P+ K + RY P A ++ +
Sbjct: 57 SYKSVNLYKKI--WEKDGSPLMINSLNQRNYLINKFPNFKIELGMRYGDPSICVAIKKMI 114
Query: 131 ESDGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVF 190
+ +++II YPQYSC TT S L+++ + + ++ F I +A +
Sbjct: 115 KIYNVNKLIILPMYPQYSCTTTASVLDSVCEVIKKYRNIPSIIF--IRDYADNINYINAI 172
Query: 191 SERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELG-GRNP 249
+ IK+ +K I + +++ F H +P K + GD Y T + +L R
Sbjct: 173 TNSIKKSFNK--NGIPEMLIMSF--HGIPKKYIKDGDDYLKRCNVTKKLVLSKLNFSRKK 228
Query: 250 HRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIE 304
+ +QSK G +PW+ P T + I K+G+K++ ++ F ++ +ETL E+ I+
Sbjct: 229 VIMSFQSKFGNIPWITPITSEVISFLPKKGIKNIQVICPGFSSDCLETLEEIKIQ 283
>UniRef50_Q9CFB4 Cluster: Ferrochelatase; n=3; Lactococcus
lactis|Rep: Ferrochelatase - Lactococcus lactis subsp.
lactis (Streptococcus lactis)
Length = 314
Score = 84.2 bits (199), Expect = 4e-15
Identities = 78/294 (26%), Positives = 134/294 (45%), Gaps = 31/294 (10%)
Query: 21 KTAIVMLNMGGPET--TDQVGDYLHRIMTDRDMIQ------LPVQSKLGPWIASRRTEEV 72
K I+++ +G P + D V DYL + D +IQ LP+ + + + +++ E+
Sbjct: 4 KKGILLVALGTPRSCEADDVRDYLKEFLGDPLVIQKPRWLWLPILNGIILKVRPQKSAEM 63
Query: 73 KKKYSEIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVES 132
KK GSP++ +T +Q L Q + E + A Y P + E++
Sbjct: 64 YKKIWT-DEGSPLMIYTVAQAKQL-----QDMREDFDVRF--AMTYGEPRIDKVIAEMKE 115
Query: 133 DGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSE 192
G + + + YPQYS T + + + K +I + + + + +E
Sbjct: 116 SGVEEITVLPLYPQYSLTTVEPVIQQVKKI--------DDKIKVIRDFHKVESYSDLLAE 167
Query: 193 RIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRG-DTYPHEVASTVSRTMEELGGRNP-H 250
I+EK D D L+L + H +PL V++ D Y + T + +LG R +
Sbjct: 168 SIREKWQANDY----DKLVL-SYHGIPLSYVTKKKDAYEEQCKETTRLVVSKLGLREEEY 222
Query: 251 RLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIE 304
+QSK GP WL+P T D + K+ K +++ AFV + +ETL EL+IE
Sbjct: 223 EHTYQSKFGPEKWLEPATIDRVAELPKENAKKVLICSPAFVADCLETLFELEIE 276
>UniRef50_P28602 Cluster: Ferrochelatase; n=19; Proteobacteria|Rep:
Ferrochelatase - Bradyrhizobium japonicum
Length = 345
Score = 83.4 bits (197), Expect = 7e-15
Identities = 77/295 (26%), Positives = 125/295 (42%), Gaps = 27/295 (9%)
Query: 21 KTAIVMLNMGGPETTDQVGD--YLHRIMTDRDMIQ---LPVQSKLGPWIASRRTEEVKKK 75
+ ++++N+G P+T D G YL ++D +I+ L + L I R
Sbjct: 20 RVGVLLVNLGTPDTADAPGVRVYLKEFLSDARVIEDQGLVWKVVLNGIILRSRPRTKALD 79
Query: 76 YSEIGGG----SPILKWTNSQGSLLTQALDQMLPESAPHKHYV---AFRYVPPFTEDAFR 128
Y +I SP+ T SQ L AL H V A RY P +
Sbjct: 80 YQKIWNNEKNESPLKTITRSQSDKLAAALSD-------RDHVVVDWAMRYGNPSIKSGID 132
Query: 129 EVESDGADRVIIFSQYPQYSCATTGSSLNAIADFY-RNRTTPANVKFSLIERWASHKLLA 187
+ ++G DR++ YPQYS +T+ + + + R R P + + +
Sbjct: 133 ALIAEGCDRILAVPLYPQYSASTSATVCDEVFRVLARLRAQPT---LRVTPPYYEDEAYI 189
Query: 188 KVFSERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELG-G 246
+ + I+ L K LI+ + H +P V +GD Y +T LG
Sbjct: 190 EALAVSIETHLATLPFKPE---LIVASFHGMPKSYVDKGDPYQEHCIATTEALRRRLGVD 246
Query: 247 RNPHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHEL 301
+ L +QS+ G WLQPYTD ++ AK+GV+ + +V F + +ETL E+
Sbjct: 247 ASKLLLTFQSRFGNDEWLQPYTDKTMERLAKEGVRRIAVVTPGFAADCLETLEEI 301
>UniRef50_A7BBG3 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 347
Score = 80.2 bits (189), Expect = 7e-14
Identities = 84/291 (28%), Positives = 134/291 (46%), Gaps = 22/291 (7%)
Query: 23 AIVMLNMGGPETTDQ--VGDYLHRIMTDRDMIQL-PVQSK--LGPWIASRRTEEVKKKYS 77
A+V++N+G P + V +L ++DR +I++ P+ K L I R EV KY
Sbjct: 25 ALVLVNLGTPTAPEPGPVRAFLREFLSDRRVIEMSPLLWKPILEGIILRVRPREVAGKYR 84
Query: 78 EI--GGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGA 135
I GSP++ +T Q LL + L + E VA RY P + ++G
Sbjct: 85 SIWMDEGSPLMHYTREQARLLGERLPGVRVE-------VAMRYGQPSIGSVLDRLHAEGV 137
Query: 136 DRVIIFSQYPQYSCATTGSSLNAIADFY-RNRT-TPANVKFSLIERWASHKLLAKVFSER 193
RV I YPQY+ +T + +A+A + RNR + S A + LA ER
Sbjct: 138 RRVAILPAYPQYAASTVTTINDAVAQWIGRNRDGFELRLHRSFPAAPAYIEALATAL-ER 196
Query: 194 IKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELG-GRNPHRL 252
E++ + + D +++ F HS+P+ GD Y E TV+ LG
Sbjct: 197 HWERVGRPNFLTGDRIVVSF--HSIPVAMDEAGDPYRAECRHTVAALESRLGLAMGSLTA 254
Query: 253 VWQSKVGPLPWLQPYT-DDAIKLYAKQGVKHLILVPVAFVNEHIETLHELD 302
+QS G WL P T ++ +L A + + ++ P F+ + +ETL E+D
Sbjct: 255 TFQSVFGRAEWLGPQTIEEMAELGAAKCPRVDVICP-GFMADCLETLEEID 304
>UniRef50_A0L8B7 Cluster: Ferrochelatase; n=1; Magnetococcus sp.
MC-1|Rep: Ferrochelatase - Magnetococcus sp. (strain
MC-1)
Length = 335
Score = 80.2 bits (189), Expect = 7e-14
Identities = 77/291 (26%), Positives = 130/291 (44%), Gaps = 20/291 (6%)
Query: 21 KTAIVMLNMGGPE--TTDQVGDYLHRIMTDR---DMIQLPVQSKLGPWIASRRTEEVKKK 75
+TAI+++ +G P+ T + V YL + ++DR DM +L L I R + K
Sbjct: 5 ETAILLVQLGTPDQPTEEAVRRYLRQFLSDRRVVDMNRLLWWPLLHGIILRSRPSKSAKL 64
Query: 76 YSEIGGG---SPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVES 132
Y +I SP+L +T + + + S+ + A RY P +
Sbjct: 65 YKKIWRDDKTSPLLHYTRALQQEMARRFQGR--HSSGVRVDFAMRYGNPGLRCKVGSLVR 122
Query: 133 DGADRVIIFSQYPQYSCATTGSSLNAI-ADFYRNRTTPANVKFSLIERWASHKLLAKVFS 191
+G R++I +PQY+ AT S ++ + + +R P R + +
Sbjct: 123 EGVRRLLIVPLFPQYAGATVASVMDEVMRPMHIHRLMPT-------LRVMTPYYAQDAYI 175
Query: 192 ERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHR 251
+ + L+ D D L+L + H LP + V GD Y + +T EEL R+
Sbjct: 176 DALVASLEGVDLSEPDHRLLL-SYHGLPKRHVDEGDPYENHCQTTTLLLTEELDLRHDQW 234
Query: 252 LV-WQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHEL 301
++ +QS+ G PWL+P TD K QG+K L ++ F + +ETL E+
Sbjct: 235 MMSYQSRFGSEPWLEPNTDMLFKTLPSQGIKKLTVMCPGFAADCLETLEEI 285
>UniRef50_P57779 Cluster: Ferrochelatase; n=9; Bacteria|Rep:
Ferrochelatase - Zymomonas mobilis
Length = 334
Score = 79.8 bits (188), Expect = 9e-14
Identities = 69/294 (23%), Positives = 133/294 (45%), Gaps = 21/294 (7%)
Query: 18 VKPKTAIVMLNMGGPETTDQ--VGDYLHRIMTDRDMIQLPV---QSKLGPWIASRRTEEV 72
+ K ++++N+G P+ + + YL + ++D+ +I+LP Q L I R
Sbjct: 10 ISEKIGVLLVNLGTPDAPNAKALRRYLGQFLSDQRVIELPAVFWQIILRGIILPFRAPRS 69
Query: 73 KKKYSEI--GGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREV 130
+ Y +I GSP+ T Q Q L + +P A RY P ++
Sbjct: 70 ARAYQKIWTNEGSPLAAITKKQA----QGLQKRMPNITVD---YAMRYGTPSISSRLEKL 122
Query: 131 ESDGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVF 190
+ G R+++ YPQYS A+T + + + + N++ +E + +H +
Sbjct: 123 IASGCRRILLAPLYPQYSAASTATVQDEAYRYLQKIRWQPNLR--SLEPYYTHPAYIQTL 180
Query: 191 SERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPH 250
+ I++++ D + D L+L + H +P+K GD Y + +T S+ + L P
Sbjct: 181 KKNIEDQIKALD--FKPDSLLL-SYHGMPVKTRELGDPYYFQCQAT-SQALSSLLD-IPV 235
Query: 251 RLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIE 304
+QS+ G W P TD +K + +++L + F + +ETL E+ ++
Sbjct: 236 ITSFQSRFGSQKWFTPATDMTLKELPSKNIRNLAVAMPGFSADCLETLEEIALQ 289
>UniRef50_Q88XC3 Cluster: Ferrochelatase; n=3; Lactobacillus|Rep:
Ferrochelatase - Lactobacillus plantarum
Length = 324
Score = 76.2 bits (179), Expect = 1e-12
Identities = 63/286 (22%), Positives = 127/286 (44%), Gaps = 29/286 (10%)
Query: 24 IVMLNMGGPET--TDQVGDYLHRIMTDRDMIQLPV---QSKLGPWIASRRTEEVKKKYSE 78
++++N+G P + T V YL ++D +I++P Q L I R+ Y +
Sbjct: 5 LLLVNLGSPASPRTKDVKAYLQEFLSDPSVIEMPAALWQPLLRGIILPTRSWRSATFYQD 64
Query: 79 --IGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGAD 136
+ GSP++ ++ + + Q + LP+ +A Y P + + +DG +
Sbjct: 65 SWLPQGSPLIVYSQA----ICQQVQAALPDWNVR---LAMTYGQPDIGATLKAMVADGCE 117
Query: 137 RVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKE 196
+ II +PQY+ +T G + + + I+ + + + ++ +
Sbjct: 118 KPIILPLFPQYTQSTHGG--------IHRQVEATGLPHTFIDSFYDQPTYIHLLATKVWQ 169
Query: 197 KLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLV--W 254
++F+ HS+P V GD Y E +T + E +++ +
Sbjct: 170 SYQAHHYDA-----VIFSYHSIPTAMVRHGDPYQRECEATTKAVLAERPELPADKVITAY 224
Query: 255 QSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHE 300
QSK GP+PWL+PY + + + G +++++V +FV + +ETL E
Sbjct: 225 QSKFGPMPWLKPYLKNELMQLVELGKRNVLVVTPSFVVDCLETLEE 270
>UniRef50_P72183 Cluster: Ferrochelatase; n=1; Propionibacterium
freudenreichii subsp. freudenreichii|Rep: Ferrochelatase
- Propionibacterium freudenreichii subsp. freudenreichii
Length = 352
Score = 74.5 bits (175), Expect = 3e-12
Identities = 78/295 (26%), Positives = 127/295 (43%), Gaps = 38/295 (12%)
Query: 23 AIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVKKKYSEIGGG 82
A+++ GGPE+ +V D+L R+ G I R EV+ Y+ GG
Sbjct: 6 ALLVAGFGGPESMAEVPDFLQRVS--------------GGHIPPDRLAEVEHHYARFGGV 51
Query: 83 SPILKWTNSQGSLLTQALDQMLPESAPHKHYV-AFRYVPPFTEDAFREVESDGADRVIIF 141
SP+ N+Q L AL + L A R+ P+ + A +++S G RV+
Sbjct: 52 SPV----NAQHRALAAALGEALVARGIDVPIANANRHSMPYMDQALADLQSRGIRRVLTL 107
Query: 142 --SQYPQYS-CATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKL 198
+ Y YS C L A + PA ++ ++ +A L + ++ L
Sbjct: 108 VPTPYASYSGCRAYREELLA-GTRIDDEGRPA-LQVVKLDPYADLPALVTAQVQLLRAAL 165
Query: 199 DKFDEKIRDDVLILFTAHSLPLKAVS----RGDTYPHEVASTVSRTMEEL---GGRNPHR 251
D ++FT HS+P G+ Y + + + M EL G R
Sbjct: 166 AD-----HPDAHLVFTTHSIPTAMAETSGPHGNAYIPQHLALIDAVMAELAALGLRPSWE 220
Query: 252 LVWQSKVGP--LPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIE 304
L +QS+ G PWL+P +D I A +GV+ +I P+ F+ +H+E + +LD E
Sbjct: 221 LAYQSRSGSPRTPWLEPDINDVITRLAGEGVRDVICSPIGFLTDHMEVVWDLDTE 275
>UniRef50_A6DTB4 Cluster: Ferrochelatase; n=1; Lentisphaera araneosa
HTCC2155|Rep: Ferrochelatase - Lentisphaera araneosa
HTCC2155
Length = 807
Score = 70.5 bits (165), Expect = 5e-11
Identities = 66/290 (22%), Positives = 126/290 (43%), Gaps = 17/290 (5%)
Query: 21 KTAIVMLNMGGPET--TDQVGDYLHRIMTDR---DMIQLPVQSKLGPWIASRRTEEVKKK 75
KT I+++ +G P + V YL ++D D + L +I R+ + +
Sbjct: 3 KTGILLIQLGSPASPAVPDVKSYLSEFLSDPRVVDQQNFAWKIILNCFILPSRSPKSAEA 62
Query: 76 YSEIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGA 135
Y++I G + N++ T L + + + Y ++ P + ++ + G
Sbjct: 63 YAKIWEGDTFPLFRNTES--FTAKLQEQIDDENILIEY-SYILSKPNVPHQYGKLMAAGC 119
Query: 136 DRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIK 195
+ + + +PQY ATT S + + N++F +E + + + I
Sbjct: 120 ETIRVIPLFPQYCEATTLSCKDMLEKGIAEHGKCKNIEF--VEDFHNSPSYINNVARLIS 177
Query: 196 EKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHR--LV 253
E L +LF+ H P++ V GD Y + T +++ G + L
Sbjct: 178 EDL-----ATNPPEKLLFSFHGYPIRRVRGGDPYFAQCTETGHLIADQVTGIDKENILLT 232
Query: 254 WQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDI 303
+QSK G PWL P T++ + A +G+K++ + AFV +++ETL E+ I
Sbjct: 233 FQSKFGREPWLTPGTEETLIELAHKGIKNVAVTCPAFVVDNLETLEEVGI 282
>UniRef50_Q5ZYE7 Cluster: Ferrochelatase; n=5; Legionella
pneumophila|Rep: Ferrochelatase - Legionella pneumophila
subsp. pneumophila (strain Philadelphia 1 /ATCC 33152 /
DSM 7513)
Length = 331
Score = 69.7 bits (163), Expect = 1e-10
Identities = 77/309 (24%), Positives = 139/309 (44%), Gaps = 43/309 (13%)
Query: 21 KTAIVMLNMGGPETTD--QVGDYLHRIMTDRDMIQLPVQSK---LGPWIASRRTEEVKKK 75
+ +++LN+G P D V YL +TD+ +I LP + + I R+ + +
Sbjct: 2 RRGLLLLNLGTPNNADIRAVKLYLREFLTDKRVIDLPTIPRYILVYCLILPFRSPKSAQA 61
Query: 76 YSEIGG--GSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESD 133
Y I GSP+L +SQ +L+T+ + E +K + RY P A E++
Sbjct: 62 YQSIWTEKGSPLLY--HSQ-NLVTKLQSALKDE---YKIALGMRYGTPSITTALAELKD- 114
Query: 134 GADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSER 193
+ I +PQYS A TGS++ N+ ++K +I + E
Sbjct: 115 -CHSLTILPLFPQYSSAATGSAIEKTLSHLANQEIIPSIK--IIRDFYQRP-------EY 164
Query: 194 IKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRG--DT----------------YPHEVAS 235
I+ + I+D+ +LF+ H +P + + + DT Y +
Sbjct: 165 IQAQAKIMKPYIKDNFHLLFSYHGIPERHIHKSGCDTLCPQTCTPIYDKNQACYRAQCYQ 224
Query: 236 TVSRTMEELG-GRNPHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEH 294
T +EL G + + +QS++G PW++PYTD+ +G+K++++ +FV +
Sbjct: 225 TSLLLAKELQLGTHQYTTAFQSRLGKTPWIKPYTDEIFAELISKGIKNIVVSCPSFVADC 284
Query: 295 IETLHELDI 303
+ETL E+ I
Sbjct: 285 LETLEEIGI 293
>UniRef50_O07401 Cluster: Ferrochelatase; n=1; Mycobacterium
avium|Rep: Ferrochelatase - Mycobacterium avium
Length = 335
Score = 67.7 bits (158), Expect = 4e-10
Identities = 38/105 (36%), Positives = 59/105 (56%), Gaps = 5/105 (4%)
Query: 204 KIRDDVLILFTAHSLPLKAVSR--GDTYPHEVASTVSRTMEELGGRNPHRLVWQSKVGP- 260
K+ ++FTAHS+P+ A R Y +VA +R + G H LVWQS+ GP
Sbjct: 159 KVPAGARLVFTAHSVPVAADERLGPRLYSRQVAYA-ARLVAAAAGYAEHDLVWQSRSGPP 217
Query: 261 -LPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIE 304
+ WL+P D ++ A+ G + +I+ P+ FV +HIE + +LD E
Sbjct: 218 QVRWLEPDVADHLRALAESGTRAVIVCPIGFVADHIEVVWDLDEE 262
>UniRef50_Q9HVD7 Cluster: Ferrochelatase; n=19;
Pseudomonadaceae|Rep: Ferrochelatase - Pseudomonas
aeruginosa
Length = 340
Score = 67.3 bits (157), Expect = 5e-10
Identities = 81/311 (26%), Positives = 140/311 (45%), Gaps = 46/311 (14%)
Query: 21 KTAIVMLNMGGPETT--DQVGDYLHRIMTDRDMIQLP--VQSKLGPWIASRRTEEVKKKY 76
+ A+++LN+G P++T + V YL + + D ++ LP ++ L I +R E Y
Sbjct: 3 ENALLLLNLGSPDSTRVEDVRRYLDQFLMDPYVVDLPWPLRRLLVSLILIKRPAESAHAY 62
Query: 77 SEI--GGGSPILKWTNSQGSLLTQALDQMLPESAPHKHY-VAFRYVPPFTEDAFREVESD 133
S I GSP++ +L++ L + + PH +A RY P E ++
Sbjct: 63 SSIWWDEGSPLI--------VLSRRLQEAMKPHWPHGPVELAMRYGQPAIEKVLLDLARR 114
Query: 134 GADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSER 193
G RV + YPQ++ +TT ++ + R A + L V+ +
Sbjct: 115 GIRRVTLAPLYPQFADSTTTTAEQEV------RRVIAAHRLGLEVSTLPPFYDQPVYLDA 168
Query: 194 IKEKLDKFDEKIRDDVLILFTAHSLP--------------LKAVSRGDTYPHEVA----S 235
+ E + + ++ D +L+ F H LP L A + + P +A S
Sbjct: 169 LVESVRPYLQQPHDHLLLSF--HGLPERHIRKLVKDPAHDLLAENSRNVSPEALALCYRS 226
Query: 236 TVSRTME---ELGGRNPHR--LVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAF 290
RT E E G R + +QS++G W++PYTD + ++GVK L+++ AF
Sbjct: 227 QCLRTAEAFAERAGLEQGRWSVSFQSRLGRAKWIEPYTDAKLDELVQRGVKRLLVMCPAF 286
Query: 291 VNEHIETLHEL 301
V + IETL E+
Sbjct: 287 VADCIETLEEI 297
>UniRef50_Q7MXP4 Cluster: Ferrochelatase; n=1; Porphyromonas
gingivalis|Rep: Ferrochelatase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 345
Score = 66.1 bits (154), Expect = 1e-09
Identities = 73/304 (24%), Positives = 141/304 (46%), Gaps = 33/304 (10%)
Query: 21 KTAIVMLNMGGPETTDQ--VGDYLHRIMTDRDMIQLPV---QSKLGPWIASRRTEEVKKK 75
+ +++LN+G P++ ++ V YL+ +TDR +I LP Q + I R + +K
Sbjct: 14 REVVLLLNIGSPDSPEEKDVARYLNSFLTDRRIITLPFLLRQLLVRGIITPFRKKSSAQK 73
Query: 76 YSEIGGGSPILKWTNSQGSLL-TQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDG 134
Y + S T S + T+A+ + L + H VA RY P D +E+
Sbjct: 74 YRTVWDES-----TRSFPLISHTKAIARALAHTGREVH-VAMRYGKPAVADVLKELPHGR 127
Query: 135 ADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERI 194
+ +++ +P Y+ ++ +++ R R P N+ F +++ + +H+ +V ++ I
Sbjct: 128 S--LVVLPLFPHYAMSSYETAVEHCKAEIR-RLCP-NLSFRVVQPFYAHEAYIRVLADNI 183
Query: 195 KEKLDK-FDEKIRD------DVLILFTAHSLPLK----AVSRGD-----TYPHEVASTVS 238
+ L K FD+ I D L T +L L+ + D Y ++ T +
Sbjct: 184 RPYLTKPFDKLILSYHGIPRDHLDKTTRQALNLRHPEGCCTEEDPTANVCYRYQTYRTTA 243
Query: 239 RTMEELG-GRNPHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIET 297
E LG V+QS+VG WL+PY + + + ++ K +++ +FV + +E+
Sbjct: 244 LIREALGLAEEQVEQVFQSRVGHTEWLRPYLIERLSAWPQEETKRILIACPSFVCDCLES 303
Query: 298 LHEL 301
L E+
Sbjct: 304 LEEV 307
>UniRef50_Q1DC34 Cluster: Ferrochelatase; n=3; Myxococcales|Rep:
Ferrochelatase - Myxococcus xanthus (strain DK 1622)
Length = 364
Score = 64.9 bits (151), Expect = 3e-09
Identities = 79/318 (24%), Positives = 135/318 (42%), Gaps = 53/318 (16%)
Query: 21 KTAIVMLNMGGPET--TDQVGDYLHRIMTDRDMIQLPVQSKLGPW------IASRRTEEV 72
K ++++N+G P+ T V YL + D +I + LG W I R +
Sbjct: 7 KRGLLLVNLGTPDAPQTGPVRRYLREFLNDPRVIDI---HPLGRWALLNFIILPMRPAKS 63
Query: 73 KKKYSEIG--GGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREV 130
+ Y +I GSP+L ++ + L Q +++ E ++ +A RY P D +
Sbjct: 64 AEAYRKIWMKEGSPLLVYSQA---LAAQVAERLAGE---YEVVLAMRYGSPSIPDGIAAL 117
Query: 131 ESDGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKF-SLIERWASHKLLAKV 189
++ G + YPQ + ++T SSL A Y +V F + + H
Sbjct: 118 KARGVSEFTVLPLYPQEAASSTASSL---ARTYEVLAQSWDVPFVRAVPAFFEHPGFLDA 174
Query: 190 FSERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNP 249
F+ + +D R D +LF+ H LP + + + D ST S + + N
Sbjct: 175 FTAVARPVIDD----ARADY-VLFSFHGLPERHMRKSDPTGTHCLSTAS-CCDAMTDANR 228
Query: 250 H------------------------RLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLIL 285
H + +QS++G PW++PYTD + AK+GVK L +
Sbjct: 229 HCYRAQSYATARGLAQRLGLPAEGWSVSFQSRLGRTPWVKPYTDVVLPELAKKGVKRLAV 288
Query: 286 VPVAFVNEHIETLHELDI 303
+ AFV + +ETL E+ +
Sbjct: 289 MCPAFVADCLETLEEIGL 306
>UniRef50_Q6AB01 Cluster: Ferrochelatase, HemH; n=1;
Propionibacterium acnes|Rep: Ferrochelatase, HemH -
Propionibacterium acnes
Length = 683
Score = 63.7 bits (148), Expect = 6e-09
Identities = 73/308 (23%), Positives = 131/308 (42%), Gaps = 37/308 (12%)
Query: 20 PKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVKKKYSEI 79
P +A+++++ GGP + ++V +L R+ R I R +V + Y
Sbjct: 15 PYSAVLVVSFGGPRSPEEVMPFLRRVSHGR--------------IPEERLADVARHYDRF 60
Query: 80 GGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYV-AFRYVPPFTEDAFREVESDGADRV 138
GG SPI N + A+ L + R PF E+A ++ + G RV
Sbjct: 61 GGVSPI----NDATDVFVNAIGNELRRHGVRVPVLLGNRNGTPFLEEALTDMHAHGVRRV 116
Query: 139 --IIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKE 196
++ S Y YS A A + T +++ + + + +E + +
Sbjct: 117 LAVVTSAYASYSGCRQYREEIATALAHAGIT---DMQVDKVPPFNEAPGFIRANAEALMQ 173
Query: 197 KLDKFDEKIRDDVLILFTAHSLPLK------AVSRGDTY--PHE-VASTVSRTMEELGGR 247
+ + ++F HS+P A G Y H+ V V+ + ++ G
Sbjct: 174 AFMRIPPTPLEATRVVFVTHSIPDSMQDASGAGQPGTDYISQHKAVCERVAGQVRQVFGN 233
Query: 248 NPH-RLVWQSKVG-PL-PWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIE 304
P L + S+ G P PWL+P D ++ +QGV+ +++ P+ FV +H+E +++LD E
Sbjct: 234 MPQWDLAYCSRSGRPSDPWLEPDIIDHLRSLPEQGVQSVVVAPIGFVADHMEVVNDLDYE 293
Query: 305 YCDEVAKE 312
E AKE
Sbjct: 294 -AAEAAKE 300
>UniRef50_Q83FA4 Cluster: Ferrochelatase; n=4; Coxiella
burnetii|Rep: Ferrochelatase - Coxiella burnetii
Length = 343
Score = 60.1 bits (139), Expect = 8e-08
Identities = 72/315 (22%), Positives = 139/315 (44%), Gaps = 52/315 (16%)
Query: 21 KTAIVMLNMGGPE--TTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASR------RTEEV 72
K ++++N+G P+ + V YL + ++D +I +P L WI R +
Sbjct: 8 KIGVLLINLGTPDEPSVPAVRRYLRQFLSDPKVIDVP---SLVRWIIVHLCILPFRPKRS 64
Query: 73 KKKYSEIG--GGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREV 130
K Y +I GSP+L ++ +L + + + L + + RY P E A +++
Sbjct: 65 AKLYQKIWMPEGSPLLVYSE----MLRERVGETLGDDFCVA--LGMRYGKPSIETALKKL 118
Query: 131 ESDGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVF 190
+ ++I+ +PQYS +TT S+L + R + + ++I+R+
Sbjct: 119 QEAQCRQLIVLPLFPQYSTSTTASALEEV------RAKNSFKEMTVIDRFFEEPHYIDSM 172
Query: 191 SERIKEKLDKFDEKIRDDVLILFTAHSLPLK---------------------AVSRGDTY 229
+ I E L++F LF+ H LP + + S + Y
Sbjct: 173 TTLIHENLNEFQPD-----YFLFSYHGLPERHLVKSGCQLAICNRKNNCSPISSSNENCY 227
Query: 230 PHEVASTVSRTMEELG-GRNPHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPV 288
+ T ++L + + +QS++G W++PYTD + +K+G+K L++V
Sbjct: 228 RAQCFETSRLIAKKLNLTDQQYGVAFQSRLGRAKWIEPYTDKYLIELSKKGIKKLMVVCP 287
Query: 289 AFVNEHIETLHELDI 303
+F + +ETL E+ I
Sbjct: 288 SFPVDCLETLEEIGI 302
>UniRef50_A5V0K6 Cluster: Ferrochelatase; n=2; Roseiflexus|Rep:
Ferrochelatase - Roseiflexus sp. RS-1
Length = 314
Score = 56.4 bits (130), Expect = 1e-06
Identities = 51/223 (22%), Positives = 85/223 (38%), Gaps = 5/223 (2%)
Query: 90 NSQGSLLTQALDQMLPESAPHKHYVAF--RYVPPFTEDAFREVESDGADRVIIFSQYPQY 147
+S L ALD L + + V R+ P DA + G V++ P
Sbjct: 60 DSAARRLAAALDDELRQRYGSRFQVVLGARHWHPTVADALAHLVQTGIQYVLVLPLSPVA 119
Query: 148 SCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKLDKFDEKIRD 207
S + S + P V+ LI W + L++ + R
Sbjct: 120 SQMSLRSYQETLEHAQTEVAQP--VRLHLIPDWPDLPGYRSALTINATLALERLPDCDRS 177
Query: 208 DVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQSKVGPLPWLQPY 267
+L AHS+ A Y + T+ R + LG + L + GP WL P
Sbjct: 178 RTALLAIAHSVAESARKPETEYQWRLRQTMQRLVSTLGCGAGY-LAYYGAGGPGQWLGPD 236
Query: 268 TDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVA 310
A+ A+ G++H++ VP+ V +++E +ELD+ + A
Sbjct: 237 VLSALDEIARAGLRHVLAVPINTVYDNVEVCYELDVRMAERAA 279
>UniRef50_Q9HLB8 Cluster: Ferrochelatase; n=2; Thermoplasma|Rep:
Ferrochelatase - Thermoplasma acidophilum
Length = 308
Score = 56.0 bits (129), Expect = 1e-06
Identities = 67/285 (23%), Positives = 119/285 (41%), Gaps = 38/285 (13%)
Query: 21 KTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVKKKYSEIG 80
K+A+++L+ G PE + + +YL I + PV + EE +KY G
Sbjct: 2 KSALLLLSYGSPERIEDLDEYLKNIFNGK-----PVPESV--------REENLRKYEMFG 48
Query: 81 GGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRVII 140
G SP + S L + + + +KH+ P E+A + + S D ++
Sbjct: 49 GRSPSNRIIESIARKLHEKIGDDMDVILAYKHW------NPSIEEAVKGLGS--YDNIVA 100
Query: 141 FSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKLDK 200
+ YS S LN + R ++F + A+ L +++ I E
Sbjct: 101 IPLFSFYSQNVKDSYLNPLESALRRYGFSPRLEF--VNGLANSDLFLPMWANIISEDAS- 157
Query: 201 FDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQSKVGP 260
+D LF AHSLP A R + Y + + + + LG R + + G
Sbjct: 158 ------EDSFYLFDAHSLP--APDREEDYLFWLRYSTYKISQILG---LSRSDFGFQGGH 206
Query: 261 LPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEY 305
L WL P D + + + ++P++F+ +H+E L++LD E+
Sbjct: 207 LGWLGPSIYDVLN---RIDASKITVIPISFLYDHLEILYDLDYEF 248
>UniRef50_Q9BHB8 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 374
Score = 55.6 bits (128), Expect = 2e-06
Identities = 72/305 (23%), Positives = 119/305 (39%), Gaps = 34/305 (11%)
Query: 17 AVKPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVKKKY 76
A P+T I++L+ G P ++L +++P + E +K
Sbjct: 25 ARSPQTEIILLHAGQPWNEFHAKEFLKNQSAQSMRLRMPNFVHTLIANGKLKNENLKGCI 84
Query: 77 SEIGGGSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGAD 136
+ + + G + ++LD ++PE P K F++ ED +E++S +
Sbjct: 85 AAYKNVPSLESQVDRLGKKIEESLDTVVPEHGPFKVSRLFQFDEVSFEDQLKEIKSHRSQ 144
Query: 137 RVIIFSQYPQYSCATTGSSLNAIADFYRNRTTP-----ANVKFSLIE------------- 178
I YP +S + + L A ++P N+ S IE
Sbjct: 145 HYIFMPLYPHFSAIDSETLLVKSAKIIEQTSSPLVQGNKNITSSRIEQNSDYSYDVSAIW 204
Query: 179 RWASHKLLAKVFSERIKEKLDKFDEKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVS 238
RW +H +LA +S +IKE L K D ++F A P K Y V ++
Sbjct: 205 RWNNHPILADYWSSKIKEVLPKLDG-------VVFAA---PRKFTC---NY-GPVFASCE 250
Query: 239 RTMEELGGRNPHRLVWQSKVG--PLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIE 296
RTM +LG P RL + S LP +Q K+ + +VP+ V E
Sbjct: 251 RTMNQLGDLIPWRLGFYSSWDSFDLPSMQGVASQVQKIRKTSESGKVAVVPITDVIETFN 310
Query: 297 TLHEL 301
TL+ L
Sbjct: 311 TLYTL 315
>UniRef50_Q4JSM9 Cluster: Ferrochelatase; n=1; Corynebacterium
jeikeium K411|Rep: Ferrochelatase - Corynebacterium
jeikeium (strain K411)
Length = 424
Score = 50.8 bits (116), Expect = 5e-05
Identities = 26/63 (41%), Positives = 38/63 (60%), Gaps = 3/63 (4%)
Query: 252 LVWQSKVGP--LPWLQPYTDDAIKLYAKQG-VKHLILVPVAFVNEHIETLHELDIEYCDE 308
LVWQS+ G +PWL+P D I+ A+ G + ++L PV F+ +H+E +LD E D
Sbjct: 285 LVWQSRSGSPHVPWLEPDVCDHIEARAEAGNTRAIVLCPVGFITDHMEVKWDLDTEARDA 344
Query: 309 VAK 311
AK
Sbjct: 345 AAK 347
Score = 48.8 bits (111), Expect = 2e-04
Identities = 53/220 (24%), Positives = 92/220 (41%), Gaps = 26/220 (11%)
Query: 11 STASGTAVKPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTE 70
++A A+ P + +++L+ GGPE + V +L + R I R E
Sbjct: 3 TSAETPAIAPDSGLLLLSFGGPEKAEDVVPFLENVTRGRG-------------IPRARLE 49
Query: 71 EVKKKYSEIGGGSPILKWTNSQGSLLTQALD-QMLPESAPHKHYVAFRYVPPFTEDAFRE 129
+V + Y +GG SPI N Q L + ++ ++ Y R P+ EDA ++
Sbjct: 50 KVGEHYFALGGRSPI----NDQNKQLIRNIEAELARRDIDLPVYFGNRNWEPYVEDALQQ 105
Query: 130 VESDGADRVIIF--SQYPQYS-CATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLL 186
+ DG V +F S + YS C+ L A K + ++ H
Sbjct: 106 MARDGIRHVYVFATSAWGGYSGCSQYQEDLRRAIAACEEAGLEA-PKVERLPQFHRHPTF 164
Query: 187 AKVFSERI---KEKL-DKFDEKIRDDVLILFTAHSLPLKA 222
F+ + +E+L + E++ ++FTAHS+P A
Sbjct: 165 IAEFARAVDAAREQLRAEHGEEVAAQADLVFTAHSVPTVA 204
>UniRef50_Q6L0G9 Cluster: Ferrochelatase; n=2;
Thermoplasmatales|Rep: Ferrochelatase - Picrophilus
torridus
Length = 287
Score = 50.4 bits (115), Expect = 6e-05
Identities = 65/282 (23%), Positives = 118/282 (41%), Gaps = 34/282 (12%)
Query: 24 IVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVKKKYSEIGGGS 83
+++L+ G PE+ D++G+YL + G + R E +KKY G S
Sbjct: 4 LILLSYGSPESIDELGEYLSMVF-------------YGNPVPERIYNENRKKYELYNGRS 50
Query: 84 PILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVESDGADRVIIFSQ 143
P +N + + L + L E A+++ P E+ + S D +
Sbjct: 51 P----SNDILKCIEEKLKKALREY-DFDVTQAYKHWKPGIENIVED--SKDFDEIFAIPL 103
Query: 144 YPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASHKLLAKVFSERIKEKLDKFDE 203
+P + S + + A V+F + +LL + E+I + ++E
Sbjct: 104 FPFSTNNVKNSYEKPFNEALKKYNVTARVRF--LNGLEDQELLYSAWIEKISGHM--YNE 159
Query: 204 KIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQSKVGPLPW 263
LF AHSLPL S TY + + +T +R + ++ + + S+ W
Sbjct: 160 SP-----FLFAAHSLPL--YSDESTYENLIINT-ARRLSNTFLKDDYFYGFYSQGEHGKW 211
Query: 264 LQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEY 305
L P D I + + ++P+ F+ EH+E L++LDIE+
Sbjct: 212 LYPSIYDYIDKLKEYN--SVTVIPIGFIYEHLEILYDLDIEF 251
>UniRef50_A7CZ83 Cluster: Ferrochelatase; n=1; Opitutaceae bacterium
TAV2|Rep: Ferrochelatase - Opitutaceae bacterium TAV2
Length = 205
Score = 44.8 bits (101), Expect = 0.003
Identities = 37/149 (24%), Positives = 64/149 (42%), Gaps = 18/149 (12%)
Query: 21 KTAIVMLNMGGPETT--DQVGDYLHRIMTDRDMIQLPVQS----KLGPWIASRRTEEVKK 74
K A++++N+G P++T V YL + D +I P Q + I R +
Sbjct: 3 KRAVLLVNLGSPDSTRVSDVRRYLREFLGDERVIDKPAQPFRWLLVNGIITPFRAPKSAH 62
Query: 75 KYSEIG--GGSPILKWTNSQGSLLTQALDQMLPE----------SAPHKHYVAFRYVPPF 122
Y +I GSP++ + S L +AL P +AP ++A RY P
Sbjct: 63 AYQQIWTKSGSPLVVTSESVQKKLVEALRASPPSPPPANNDADPAAPPLVFLAMRYGRPS 122
Query: 123 TEDAFREVESDGADRVIIFSQYPQYSCAT 151
+ G + +++F QYP Y+ ++
Sbjct: 123 IASVLETIIKAGVEELLLFPQYPHYAMSS 151
>UniRef50_Q8YNF0 Cluster: Alr4616 protein; n=9; Cyanobacteria|Rep:
Alr4616 protein - Anabaena sp. (strain PCC 7120)
Length = 349
Score = 44.4 bits (100), Expect = 0.004
Identities = 49/202 (24%), Positives = 85/202 (42%), Gaps = 13/202 (6%)
Query: 113 YVAFRYVPPFTED-AFREVESDGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPAN 171
+ AF + PF + E++S G D+++I+ S T+G ++ + + N
Sbjct: 90 FKAFNFCAPFLPNQVLAEIKSQGFDKILIYPLLVVDSIFTSGIAIEQVNNALTETNDGEN 149
Query: 172 ---VKFSLIERWASHKLLAKVFSERIKEKL--DKFDEKIRDDVLILFTAHSLPLKAVSRG 226
I + + + + ++EK+ D + + I+ H P KA +G
Sbjct: 150 HWLKALRYIPSFYNEPEYIHLMAHLVEEKINADLATAYLPSQIGIVLMNHGCPHKA--KG 207
Query: 227 DTYPH-EVASTVSRTMEELGGRNPHRLV-WQSKVGPL-PWLQPYTDDAIKLYAKQGVKHL 283
T E + EEL + P V W + PL W QP + A K + G K +
Sbjct: 208 FTSGIVESQALYDLVREELIYKYPLISVGWLNHDTPLIEWTQPNAEQAAKNLIQLGAKVI 267
Query: 284 ILVPVAFVNEHIETLHELDIEY 305
I +P+ F E+ ETL LD+ +
Sbjct: 268 IFMPIGFATENHETL--LDVHH 287
>UniRef50_Q4QE43 Cluster: Ferrochelatase-like protein; n=21;
Leishmania|Rep: Ferrochelatase-like protein - Leishmania
major
Length = 385
Score = 41.5 bits (93), Expect = 0.029
Identities = 58/287 (20%), Positives = 112/287 (39%), Gaps = 42/287 (14%)
Query: 20 PKTAIVMLNMGGPE--TTDQVGDYLHRIMTDRDMIQLPV---QSKLGPWIASRRTEEVKK 74
P AI+++N+G T V +L ++DR +I +P S L +I R +
Sbjct: 7 PTKAILLVNLGTTTAPTAPAVRRFLREFLSDRRVIDVPRFLWYSALYGFILPFRPRRITP 66
Query: 75 KYSEI----------GG---GSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPP 121
Y I G GSP+ ++ S + + ++++ + +H A RY
Sbjct: 67 LYKGIWIKSDSGVVINGKTEGSPLTLYSESLVAKVQASVEKTSGGAVVARH--AMRYGVN 124
Query: 122 FTEDAFREVESDGAD--RVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIER 179
+ + + A +++ +PQY+ T+ S + + FY + + I
Sbjct: 125 NIPSTLKALHDEFATLRELVVLPLFPQYTSTTSASIYDEVFKFYTDTQRRSIPSLRTIRD 184
Query: 180 WASHKLLAKVFSERIKEKLDK-----------FDEKIRD---DVLILFTAHSLPLKAVSR 225
+A H + + + + + + D ++ I+ T HS+P++ V
Sbjct: 185 YAEHPVYVEALGSSLLSSIKAHVTAKAGAAKDWKSALADQLPEIGIIITYHSIPVRYVEE 244
Query: 226 GDTYPHEVASTVSRTMEELGGRNPHRL------VWQSKVGPLPWLQP 266
D YP +T + + + L V+QS+ G PWL P
Sbjct: 245 HDDYPQRCEATTAAIKAYIEAESGISLSDCLVHVYQSQFGNQPWLGP 291
>UniRef50_A7BEQ8 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 734
Score = 36.3 bits (80), Expect = 1.1
Identities = 22/87 (25%), Positives = 46/87 (52%), Gaps = 6/87 (6%)
Query: 231 HEVASTVSRTMEELGGRN--PHRLVWQSKVGPLP--WLQPYTDDAIKLYAKQG--VKHLI 284
H + + ++ + GR + LV+ S+ GP WL+P +D ++ A + +
Sbjct: 256 HALIEAIMPELQRVLGRAYLGYDLVYCSRSGPPQSRWLEPDINDFLEEIAADANPLTGAV 315
Query: 285 LVPVAFVNEHIETLHELDIEYCDEVAK 311
+VP+ F+ +H+E +++LD E + A+
Sbjct: 316 VVPIGFICDHMEVVYDLDTEAKETAAR 342
>UniRef50_A6T0P6 Cluster: Patatin-like phospholipase; n=1;
Janthinobacterium sp. Marseille|Rep: Patatin-like
phospholipase - Janthinobacterium sp. (strain Marseille)
(Minibacterium massiliensis)
Length = 730
Score = 35.5 bits (78), Expect = 1.9
Identities = 33/127 (25%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 40 DYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVKKKYSEIGGGSPILKWTNSQGSLLTQA 99
D + R +T + I + + +GPW R ++ +E+ GSPIL S G L
Sbjct: 498 DQVARYLTQQFRIGVDLGVSMGPWGDVRAGPLYRRINAEVNTGSPILPDFKSNGGGLRAR 557
Query: 100 --LDQMLPESAPHKHY-VAFRYVPPFTEDAFREVESDGADRVIIFSQYPQYSCATTGSSL 156
LDQ+ P + Y ++ F +DA+ ++E A V F ++ A GS+L
Sbjct: 558 FFLDQLDRAFLPREGYALSMNAERWFDKDAYNKLEG-RATYVKSFGEHTVSLTAAGGSNL 616
Query: 157 NAIADFY 163
++
Sbjct: 617 GTEIPYF 623
>UniRef50_A6PNJ6 Cluster: UvrD/REP helicase; n=1; Victivallis vadensis
ATCC BAA-548|Rep: UvrD/REP helicase - Victivallis
vadensis ATCC BAA-548
Length = 1235
Score = 35.5 bits (78), Expect = 1.9
Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 116 FRYVPPFTEDAFREVESDGADRVIIFSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFS 175
F + F E+ D A+R F+ +P+++ G LN D R T + ++S
Sbjct: 1071 FGFGRKFRTGEIAELLGDYAEREFRFTDWPEWNTPVDGGFLNGFIDLVFRRRTASGDRYS 1130
Query: 176 LIERWASHKL 185
L++ W +++L
Sbjct: 1131 LVD-WKTNRL 1139
>UniRef50_Q9FUU1 Cluster: Ribosomal protein S10; n=1; Daucus
carota|Rep: Ribosomal protein S10 - Daucus carota
(Carrot)
Length = 230
Score = 35.5 bits (78), Expect = 1.9
Identities = 21/72 (29%), Positives = 32/72 (44%)
Query: 10 FSTASGTAVKPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRT 69
F+++ TA P T N+ + D L + R + Q+P+ S L I RR
Sbjct: 22 FASSLFTAASPSTLFNTNNLSPVRRAFPLSDVLDPMSATRSLSQIPLASPLSNGIGGRRG 81
Query: 70 EEVKKKYSEIGG 81
EV + YS + G
Sbjct: 82 WEVNRSYSTLLG 93
>UniRef50_Q9SS89 Cluster: F4P13.20 protein; n=5; Magnoliophyta|Rep:
F4P13.20 protein - Arabidopsis thaliana (Mouse-ear
cress)
Length = 273
Score = 35.1 bits (77), Expect = 2.5
Identities = 13/43 (30%), Positives = 22/43 (51%)
Query: 141 FSQYPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWASH 183
F YP++ S ++++ + YRNR P + L+ W SH
Sbjct: 66 FYSYPRFVNHVDDSFISSLTELYRNRLRPGSTVLDLMSSWVSH 108
>UniRef50_Q91L90 Cluster: ORF162; n=2; Shrimp white spot syndrome
virus|Rep: ORF162 - White spot syndrome virus (WSSV)
Length = 283
Score = 34.7 bits (76), Expect = 3.3
Identities = 12/34 (35%), Positives = 23/34 (67%)
Query: 11 STASGTAVKPKTAIVMLNMGGPETTDQVGDYLHR 44
ST +G +PK+ +++ N+ +++D +GDYL R
Sbjct: 203 STFAGIVNRPKSVVILSNLRNSDSSDNIGDYLKR 236
>UniRef50_Q8EY34 Cluster: Ferrochelatase; n=5; Leptospira|Rep:
Ferrochelatase - Leptospira interrogans
Length = 98
Score = 34.7 bits (76), Expect = 3.3
Identities = 12/25 (48%), Positives = 21/25 (84%)
Query: 277 KQGVKHLILVPVAFVNEHIETLHEL 301
K+GVK + + P++FV++H+ETL E+
Sbjct: 7 KKGVKRVAVYPISFVSDHLETLEEI 31
>UniRef50_A4M8C8 Cluster: TPR repeat-containing protein; n=1;
Petrotoga mobilis SJ95|Rep: TPR repeat-containing
protein - Petrotoga mobilis SJ95
Length = 1055
Score = 34.7 bits (76), Expect = 3.3
Identities = 22/88 (25%), Positives = 38/88 (43%), Gaps = 8/88 (9%)
Query: 144 YPQYSCATTGSSLNAIADFYRNRTTPANVKFSLIERWA--------SHKLLAKVFSERIK 195
Y Q+ C L + DF+ N + FS+I++W S+ + + I+
Sbjct: 351 YGQFHCLLNMKDLEKVYDFFLNHSELLIKDFSIIKKWLDLIPTSFFSNNIELYYYRGVIE 410
Query: 196 EKLDKFDEKIRDDVLILFTAHSLPLKAV 223
EK FDE + D L+ H + K++
Sbjct: 411 EKYSMFDEALSDYRLVKDNIHKISNKSI 438
>UniRef50_A5UYH0 Cluster: Putative uncharacterized protein
precursor; n=2; Roseiflexus|Rep: Putative
uncharacterized protein precursor - Roseiflexus sp. RS-1
Length = 445
Score = 33.9 bits (74), Expect = 5.8
Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Query: 12 TASGTAVKPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEE 71
TA+G +KP+ V L G ++ +Y R+ + LPV +GPW
Sbjct: 64 TANGHIIKPRDRFVALPSWGVLSSRNGYEYQVRVTYRDRSVVLPVWD-VGPWNTHDDYWS 122
Query: 72 VKKKYSEIGGGSPILKWTNSQG 93
++YS++ G P+ + QG
Sbjct: 123 PDRRYSDLPPGLPMAQAARQQG 144
>UniRef50_A4WPN2 Cluster: Putative uncharacterized protein
precursor; n=1; Rhodobacter sphaeroides ATCC 17025|Rep:
Putative uncharacterized protein precursor - Rhodobacter
sphaeroides ATCC 17025
Length = 754
Score = 33.9 bits (74), Expect = 5.8
Identities = 17/66 (25%), Positives = 31/66 (46%)
Query: 233 VASTVSRTMEELGGRNPHRLVWQSKVGPLPWLQPYTDDAIKLYAKQGVKHLILVPVAFVN 292
V+ +SRT + +GG ++VWQ+ P WL+ T + + + + L PV
Sbjct: 462 VSRVLSRTAQHVGGAGFEQIVWQAAPEPTAWLRLGTGELVAMVYDPDEEVLGWAPVPVAG 521
Query: 293 EHIETL 298
++ L
Sbjct: 522 GFVDAL 527
>UniRef50_Q82BJ3 Cluster: Putative ATP/GTP-binding protein; n=1;
Streptomyces avermitilis|Rep: Putative ATP/GTP-binding
protein - Streptomyces avermitilis
Length = 1314
Score = 33.5 bits (73), Expect = 7.7
Identities = 33/145 (22%), Positives = 58/145 (40%), Gaps = 17/145 (11%)
Query: 14 SGTAVKPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDMIQLPVQSKLGPWIASRRTEEVK 73
SG +V + +GG T +Y+HR M D D++ W ++ + V
Sbjct: 511 SGMSVVLPQPQALTGLGGVGKTQVALEYVHRFMADYDLVW---------WTSAESVDNVV 561
Query: 74 KKYSEIGG--GSPILKWTNSQGSLLTQALDQMLPESAPHKHYVAFRYVPPFTEDAFREVE 131
+E+G G+P +L+++ QML P K ++ E R
Sbjct: 562 ASLAELGARIGAP----GGEDMALVSRETVQMLARGVPTKRWILIFDNADNPEQLTRYFP 617
Query: 132 SDGADRVIIFSQYPQYSCATTGSSL 156
+ G +++ S+ + AT G SL
Sbjct: 618 AGGGGHILVTSR--NQAWATQGQSL 640
>UniRef50_Q47PK5 Cluster: CRISPR-associated protein, TM1811
C-terminal; n=1; Thermobifida fusca YX|Rep:
CRISPR-associated protein, TM1811 C-terminal -
Thermobifida fusca (strain YX)
Length = 594
Score = 33.5 bits (73), Expect = 7.7
Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 2/50 (4%)
Query: 7 PPAFSTASGTAVKPKTAIVMLNMGGPETTDQVGDYLHRIMTDRDM-IQLP 55
P + G A P V+ N+ P+ T+QV DYLH+++ D D I +P
Sbjct: 201 PYGIPSTYGIASAPFRIEVLKNINDPDVTEQV-DYLHQVVQDEDTGIHIP 249
>UniRef50_A7RNJ9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 366
Score = 33.5 bits (73), Expect = 7.7
Identities = 29/124 (23%), Positives = 54/124 (43%), Gaps = 8/124 (6%)
Query: 203 EKIRDDVLILFTAHSLPLKAVSRGDTYPHEVASTVSRTMEELGGRNPHRLVWQSKVGPLP 262
+ +R +I+F SLP + +T ++V V + M+EL +NP + K+
Sbjct: 112 DSVRGLSIIIFLDLSLPNELWHTMETLLNQVKKRVHKVMDELAAKNPSAV---QKLRNDA 168
Query: 263 WLQPYTDDAIKLYAKQGVKHLILVPVAFVNEHIETLHELDIEYCDEVAKELRTISELSAR 322
W + TD K + + +P+A V + + D E +++ LR I+ +
Sbjct: 169 WEKFGTDHPDKSFVEP-----FPIPLAIVGGKYDIYQDFDPEKRKMISRALRFIAHCNGA 223
Query: 323 FLTF 326
L F
Sbjct: 224 HLQF 227
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.397
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 376,373,026
Number of Sequences: 1657284
Number of extensions: 15750108
Number of successful extensions: 39581
Number of sequences better than 10.0: 125
Number of HSP's better than 10.0 without gapping: 109
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 39152
Number of HSP's gapped (non-prelim): 163
length of query: 329
length of database: 575,637,011
effective HSP length: 101
effective length of query: 228
effective length of database: 408,251,327
effective search space: 93081302556
effective search space used: 93081302556
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 73 (33.5 bits)
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