Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001595-TA|BGIBMGA001595-PA|IPR003010|Nitrilase/cyanide
hydratase and apolipoprotein N-acyltransferase
(391 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF169559-1|AAF06739.1| 387|Homo sapiens beta-ureidopropionase p... 461 e-129
CR456375-1|CAG30261.1| 384|Homo sapiens Em:AP000355.2 protein. 460 e-129
BC139843-1|AAI39844.2| 389|Homo sapiens UPB1 protein protein. 460 e-129
BC131703-1|AAI31704.1| 384|Homo sapiens UPB1 protein protein. 460 e-129
AF163312-1|AAF06735.1| 384|Homo sapiens beta-ureidopropionase p... 460 e-129
AB013885-1|BAA88634.1| 384|Homo sapiens beta-ureidopropionase p... 460 e-129
CR541846-1|CAG46644.1| 327|Homo sapiens NIT1 protein. 60 2e-08
CR541814-1|CAG46613.1| 327|Homo sapiens NIT1 protein. 60 2e-08
AL591806-16|CAI15379.1| 327|Homo sapiens nitrilase 1 protein. 60 2e-08
AF069987-1|AAC39907.1| 327|Homo sapiens nitrilase 1 protein. 60 2e-08
AF069984-1|AAC39901.1| 327|Homo sapiens nitrilase homolog 1 pro... 60 2e-08
BC020620-1|AAH20620.1| 276|Homo sapiens nitrilase family, membe... 54 7e-07
BC107890-1|AAI07891.1| 276|Homo sapiens nitrilase family, membe... 54 9e-07
AF284574-1|AAF87103.1| 276|Homo sapiens Nit protein 2 protein. 54 9e-07
AF260334-1|AAG44665.1| 276|Homo sapiens CUA002 protein. 54 9e-07
BC046149-1|AAH46149.1| 243|Homo sapiens NIT1 protein protein. 45 5e-04
AL591806-17|CAI15380.1| 243|Homo sapiens nitrilase 1 protein. 45 5e-04
X61972-1|CAA43964.1| 221|Homo sapiens macropain subunit iota pr... 33 1.7
X59417-1|CAA42052.1| 246|Homo sapiens prosomal P27K protein pro... 33 1.7
CR456944-1|CAG33225.1| 246|Homo sapiens PSMA6 protein. 33 1.7
BC070137-1|AAH70137.1| 246|Homo sapiens proteasome (prosome, ma... 33 1.7
BC023659-1|AAH23659.1| 246|Homo sapiens proteasome (prosome, ma... 33 1.7
BC022354-1|AAH22354.1| 246|Homo sapiens proteasome (prosome, ma... 33 1.7
BC017882-1|AAH17882.1| 246|Homo sapiens proteasome (prosome, ma... 33 1.7
BC002979-1|AAH02979.1| 246|Homo sapiens proteasome (prosome, ma... 33 1.7
>AF169559-1|AAF06739.1| 387|Homo sapiens beta-ureidopropionase
protein.
Length = 387
Score = 461 bits (1136), Expect = e-129
Identities = 220/384 (57%), Positives = 271/384 (70%), Gaps = 2/384 (0%)
Query: 4 ETHSLESIINNNLTGRDLEEFNRIHFGRRNNLEIKLKESSIXXXXXXXXXXXXXXFPAKD 63
E SLE + +L DL+E R+ +G+ ++ L + F A +
Sbjct: 5 EWKSLEECLEKHLPLPDLQEVKRVLYGKELR-KLDLPREAFEAASREDFELQGYAFEAAE 63
Query: 64 EQTRPPRIVKVGIVQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNM 123
EQ R PRIV VG+VQ+ I +P + PV EQ A+ ++K I++VA GVNIICFQE W M
Sbjct: 64 EQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEAWTM 123
Query: 124 PFAFCTREKQPWCEFAESAEDGPTTTFLRELAIKYAMVIVSSILERDEKHSDILWNTAVV 183
PFAFCTREK PW EFAESAEDGPTT F ++LA + MV+VS ILERD +H D+LWNTAVV
Sbjct: 124 PFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWNTAVV 183
Query: 184 ISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFATRYGKIAVNICFGRHHVLNWM 243
IS++G V+GK RKNHIPRVGDFNES YYMEGN GHPVF T++G+IAVNIC+GRHH LNW+
Sbjct: 184 ISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPLNWL 243
Query: 244 MFGQNGAEIVFNPSATI-AGEGGSEYMWNVEARNAAITNCYFTAAINRVGYEEFPNEFTS 302
M+ NGAEI+FNPSATI A SE +W +EARNAAI N FT AINRVG E FPNEFTS
Sbjct: 244 MYSINGAEIIFNPSATIGALRSLSESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFTS 303
Query: 303 ADGKPAHKDLGLFYGSSYFCGPDGVRCPGLSRTRDGLLIAAVDLNLNRQIKDRRCYYMTQ 362
DGK AH+D G FYGSSY PD R PGLSR+RDGLL+A +DLNL +Q+ D + MT
Sbjct: 304 GDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTG 363
Query: 363 RLDMYVNSLSKVLELDYKPQVVHE 386
R +MY L++ ++ +Y P +V E
Sbjct: 364 RYEMYARELAEAVKSNYSPTIVKE 387
>CR456375-1|CAG30261.1| 384|Homo sapiens Em:AP000355.2 protein.
Length = 384
Score = 460 bits (1135), Expect = e-129
Identities = 219/383 (57%), Positives = 270/383 (70%), Gaps = 3/383 (0%)
Query: 4 ETHSLESIINNNLTGRDLEEFNRIHFGRRNNLEIKLKESSIXXXXXXXXXXXXXXFPAKD 63
E SLE + +L DL+E R+ +G+ ++ L + F A +
Sbjct: 5 EWKSLEECLEKHLPLPDLQEVKRVLYGKELR-KLDLPREAFEAASREDFELQGYAFEAAE 63
Query: 64 EQTRPPRIVKVGIVQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNM 123
EQ R PRIV VG+VQ+ I +P + PV EQ A+ ++K I++VA GVNIICFQE W M
Sbjct: 64 EQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEAWTM 123
Query: 124 PFAFCTREKQPWCEFAESAEDGPTTTFLRELAIKYAMVIVSSILERDEKHSDILWNTAVV 183
PFAFCTREK PW EFAESAEDGPTT F ++LA + MV+VS ILERD +H D+LWNTAVV
Sbjct: 124 PFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWNTAVV 183
Query: 184 ISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFATRYGKIAVNICFGRHHVLNWM 243
IS++G V+GK RKNHIPRVGDFNES YYMEGN GHPVF T++G+IAVNIC+GRHH LNW+
Sbjct: 184 ISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPLNWL 243
Query: 244 MFGQNGAEIVFNPSATIAGEGGSEYMWNVEARNAAITNCYFTAAINRVGYEEFPNEFTSA 303
M+ NGAEI+FNPSATI SE +W +EARNAAI N FT AINRVG E FPNEFTS
Sbjct: 244 MYSINGAEIIFNPSATIGAL--SESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFTSG 301
Query: 304 DGKPAHKDLGLFYGSSYFCGPDGVRCPGLSRTRDGLLIAAVDLNLNRQIKDRRCYYMTQR 363
DGK AH+D G FYGSSY PD R PGLSR+RDGLL+A +DLNL +Q+ D + MT R
Sbjct: 302 DGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTGR 361
Query: 364 LDMYVNSLSKVLELDYKPQVVHE 386
+MY L++ ++ +Y P +V E
Sbjct: 362 YEMYARELAEAVKSNYSPTIVKE 384
>BC139843-1|AAI39844.2| 389|Homo sapiens UPB1 protein protein.
Length = 389
Score = 460 bits (1135), Expect = e-129
Identities = 219/383 (57%), Positives = 270/383 (70%), Gaps = 3/383 (0%)
Query: 4 ETHSLESIINNNLTGRDLEEFNRIHFGRRNNLEIKLKESSIXXXXXXXXXXXXXXFPAKD 63
E SLE + +L DL+E R+ +G+ ++ L + F A +
Sbjct: 5 EWKSLEECLEKHLPLPDLQEVKRVLYGKELR-KLDLPREAFEAASREDFELQGYAFEAAE 63
Query: 64 EQTRPPRIVKVGIVQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNM 123
EQ R PRIV VG+VQ+ I +P + PV EQ A+ ++K I++VA GVNIICFQE W M
Sbjct: 64 EQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEAWTM 123
Query: 124 PFAFCTREKQPWCEFAESAEDGPTTTFLRELAIKYAMVIVSSILERDEKHSDILWNTAVV 183
PFAFCTREK PW EFAESAEDGPTT F ++LA + MV+VS ILERD +H D+LWNTAVV
Sbjct: 124 PFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWNTAVV 183
Query: 184 ISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFATRYGKIAVNICFGRHHVLNWM 243
IS++G V+GK RKNHIPRVGDFNES YYMEGN GHPVF T++G+IAVNIC+GRHH LNW+
Sbjct: 184 ISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPLNWL 243
Query: 244 MFGQNGAEIVFNPSATIAGEGGSEYMWNVEARNAAITNCYFTAAINRVGYEEFPNEFTSA 303
M+ NGAEI+FNPSATI SE +W +EARNAAI N FT AINRVG E FPNEFTS
Sbjct: 244 MYSINGAEIIFNPSATIGAL--SESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFTSG 301
Query: 304 DGKPAHKDLGLFYGSSYFCGPDGVRCPGLSRTRDGLLIAAVDLNLNRQIKDRRCYYMTQR 363
DGK AH+D G FYGSSY PD R PGLSR+RDGLL+A +DLNL +Q+ D + MT R
Sbjct: 302 DGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTGR 361
Query: 364 LDMYVNSLSKVLELDYKPQVVHE 386
+MY L++ ++ +Y P +V E
Sbjct: 362 YEMYARELAEAVKSNYSPTIVKE 384
>BC131703-1|AAI31704.1| 384|Homo sapiens UPB1 protein protein.
Length = 384
Score = 460 bits (1135), Expect = e-129
Identities = 219/383 (57%), Positives = 270/383 (70%), Gaps = 3/383 (0%)
Query: 4 ETHSLESIINNNLTGRDLEEFNRIHFGRRNNLEIKLKESSIXXXXXXXXXXXXXXFPAKD 63
E SLE + +L DL+E R+ +G+ ++ L + F A +
Sbjct: 5 EWKSLEECLEKHLPLPDLQEVKRVLYGKELR-KLDLPREAFEAASREDFELQGYAFEAAE 63
Query: 64 EQTRPPRIVKVGIVQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNM 123
EQ R PRIV VG+VQ+ I +P + PV EQ A+ ++K I++VA GVNIICFQE W M
Sbjct: 64 EQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEAWTM 123
Query: 124 PFAFCTREKQPWCEFAESAEDGPTTTFLRELAIKYAMVIVSSILERDEKHSDILWNTAVV 183
PFAFCTREK PW EFAESAEDGPTT F ++LA + MV+VS ILERD +H D+LWNTAVV
Sbjct: 124 PFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWNTAVV 183
Query: 184 ISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFATRYGKIAVNICFGRHHVLNWM 243
IS++G V+GK RKNHIPRVGDFNES YYMEGN GHPVF T++G+IAVNIC+GRHH LNW+
Sbjct: 184 ISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPLNWL 243
Query: 244 MFGQNGAEIVFNPSATIAGEGGSEYMWNVEARNAAITNCYFTAAINRVGYEEFPNEFTSA 303
M+ NGAEI+FNPSATI SE +W +EARNAAI N FT AINRVG E FPNEFTS
Sbjct: 244 MYSINGAEIIFNPSATIGAL--SESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFTSG 301
Query: 304 DGKPAHKDLGLFYGSSYFCGPDGVRCPGLSRTRDGLLIAAVDLNLNRQIKDRRCYYMTQR 363
DGK AH+D G FYGSSY PD R PGLSR+RDGLL+A +DLNL +Q+ D + MT R
Sbjct: 302 DGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTGR 361
Query: 364 LDMYVNSLSKVLELDYKPQVVHE 386
+MY L++ ++ +Y P +V E
Sbjct: 362 YEMYARELAEAVKSNYSPTIVKE 384
>AF163312-1|AAF06735.1| 384|Homo sapiens beta-ureidopropionase
protein.
Length = 384
Score = 460 bits (1135), Expect = e-129
Identities = 219/383 (57%), Positives = 270/383 (70%), Gaps = 3/383 (0%)
Query: 4 ETHSLESIINNNLTGRDLEEFNRIHFGRRNNLEIKLKESSIXXXXXXXXXXXXXXFPAKD 63
E SLE + +L DL+E R+ +G+ ++ L + F A +
Sbjct: 5 EWKSLEECLEKHLPLPDLQEVKRVLYGKELR-KLDLPREAFEAASREDFELQGYAFEAAE 63
Query: 64 EQTRPPRIVKVGIVQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNM 123
EQ R PRIV VG+VQ+ I +P + PV EQ A+ ++K I++VA GVNIICFQE W M
Sbjct: 64 EQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEAWTM 123
Query: 124 PFAFCTREKQPWCEFAESAEDGPTTTFLRELAIKYAMVIVSSILERDEKHSDILWNTAVV 183
PFAFCTREK PW EFAESAEDGPTT F ++LA + MV+VS ILERD +H D+LWNTAVV
Sbjct: 124 PFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWNTAVV 183
Query: 184 ISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFATRYGKIAVNICFGRHHVLNWM 243
IS++G V+GK RKNHIPRVGDFNES YYMEGN GHPVF T++G+IAVNIC+GRHH LNW+
Sbjct: 184 ISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPLNWL 243
Query: 244 MFGQNGAEIVFNPSATIAGEGGSEYMWNVEARNAAITNCYFTAAINRVGYEEFPNEFTSA 303
M+ NGAEI+FNPSATI SE +W +EARNAAI N FT AINRVG E FPNEFTS
Sbjct: 244 MYSINGAEIIFNPSATIGAL--SESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFTSG 301
Query: 304 DGKPAHKDLGLFYGSSYFCGPDGVRCPGLSRTRDGLLIAAVDLNLNRQIKDRRCYYMTQR 363
DGK AH+D G FYGSSY PD R PGLSR+RDGLL+A +DLNL +Q+ D + MT R
Sbjct: 302 DGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTGR 361
Query: 364 LDMYVNSLSKVLELDYKPQVVHE 386
+MY L++ ++ +Y P +V E
Sbjct: 362 YEMYARELAEAVKSNYSPTIVKE 384
>AB013885-1|BAA88634.1| 384|Homo sapiens beta-ureidopropionase
protein.
Length = 384
Score = 460 bits (1135), Expect = e-129
Identities = 219/383 (57%), Positives = 270/383 (70%), Gaps = 3/383 (0%)
Query: 4 ETHSLESIINNNLTGRDLEEFNRIHFGRRNNLEIKLKESSIXXXXXXXXXXXXXXFPAKD 63
E SLE + +L DL+E R+ +G+ ++ L + F A +
Sbjct: 5 EWKSLEECLEKHLPLPDLQEVKRVLYGKELR-KLDLPREAFEAASREDFELQGYAFEAAE 63
Query: 64 EQTRPPRIVKVGIVQHSIAVPTDRPVNEQKKAIFNKVKKIIDVAGQEGVNIICFQELWNM 123
EQ R PRIV VG+VQ+ I +P + PV EQ A+ ++K I++VA GVNIICFQE W M
Sbjct: 64 EQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEAWTM 123
Query: 124 PFAFCTREKQPWCEFAESAEDGPTTTFLRELAIKYAMVIVSSILERDEKHSDILWNTAVV 183
PFAFCTREK PW EFAESAEDGPTT F ++LA + MV+VS ILERD +H D+LWNTAVV
Sbjct: 124 PFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWNTAVV 183
Query: 184 ISDTGNVIGKHRKNHIPRVGDFNESNYYMEGNTGHPVFATRYGKIAVNICFGRHHVLNWM 243
IS++G V+GK RKNHIPRVGDFNES YYMEGN GHPVF T++G+IAVNIC+GRHH LNW+
Sbjct: 184 ISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPLNWL 243
Query: 244 MFGQNGAEIVFNPSATIAGEGGSEYMWNVEARNAAITNCYFTAAINRVGYEEFPNEFTSA 303
M+ NGAEI+FNPSATI SE +W +EARNAAI N FT AINRVG E FPNEFTS
Sbjct: 244 MYSINGAEIIFNPSATIGAL--SESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFTSG 301
Query: 304 DGKPAHKDLGLFYGSSYFCGPDGVRCPGLSRTRDGLLIAAVDLNLNRQIKDRRCYYMTQR 363
DGK AH+D G FYGSSY PD R PGLSR+RDGLL+A +DLNL +Q+ D + MT R
Sbjct: 302 DGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTGR 361
Query: 364 LDMYVNSLSKVLELDYKPQVVHE 386
+MY L++ ++ +Y P +V E
Sbjct: 362 YEMYARELAEAVKSNYSPTIVKE 384
>CR541846-1|CAG46644.1| 327|Homo sapiens NIT1 protein.
Length = 327
Score = 59.7 bits (138), Expect = 2e-08
Identities = 60/207 (28%), Positives = 89/207 (42%), Gaps = 25/207 (12%)
Query: 169 RDEKHSDILWNTAVVISDTGNVIGKHRKNH-----IPRVGDFNESNYYMEGNTGHPVFAT 223
+D + + ++N V+++ G V+ +RK H IP G ESN M G + +T
Sbjct: 134 QDWEQTQKIYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVST 193
Query: 224 RYGKIAVNICFGRHHVLNWMMFGQNGAEIVFNPSATIAGEGGSEYMWNVEARNAAI-TNC 282
GKI + +C+ + Q GAEI+ PSA + G + W V R AI T C
Sbjct: 194 PAGKIGLAVCYDMRFPELSLALAQAGAEILTYPSAFGSITGPAH--WEVLLRARAIETQC 251
Query: 283 YFTAAINRVGYEEFPNEFTSADGKPAHKDLGLFYGSSYFCGPDGVRCPGLSRTRDGLLIA 342
Y AA + G+ H + YG S P G S GL +A
Sbjct: 252 YVVAA--------------AQCGR--HHEKRASYGHSMVVDPWGTVVARCSE-GPGLCLA 294
Query: 343 AVDLNLNRQIKDRRCYYMTQRLDMYVN 369
+DLN RQ++ + +R D+Y N
Sbjct: 295 RIDLNYLRQLRRHLPVFQHRRPDLYGN 321
>CR541814-1|CAG46613.1| 327|Homo sapiens NIT1 protein.
Length = 327
Score = 59.7 bits (138), Expect = 2e-08
Identities = 60/207 (28%), Positives = 89/207 (42%), Gaps = 25/207 (12%)
Query: 169 RDEKHSDILWNTAVVISDTGNVIGKHRKNH-----IPRVGDFNESNYYMEGNTGHPVFAT 223
+D + + ++N V+++ G V+ +RK H IP G ESN M G + +T
Sbjct: 134 QDWEQTQKIYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVST 193
Query: 224 RYGKIAVNICFGRHHVLNWMMFGQNGAEIVFNPSATIAGEGGSEYMWNVEARNAAI-TNC 282
GKI + +C+ + Q GAEI+ PSA + G + W V R AI T C
Sbjct: 194 PAGKIGLAVCYDMRFPELSLALAQAGAEILTYPSAFGSITGPAH--WEVLLRARAIETQC 251
Query: 283 YFTAAINRVGYEEFPNEFTSADGKPAHKDLGLFYGSSYFCGPDGVRCPGLSRTRDGLLIA 342
Y AA + G+ H + YG S P G S GL +A
Sbjct: 252 YVVAA--------------AQCGR--HHEKRASYGHSMVVDPWGTVVARCSE-GPGLCLA 294
Query: 343 AVDLNLNRQIKDRRCYYMTQRLDMYVN 369
+DLN RQ++ + +R D+Y N
Sbjct: 295 RIDLNYLRQLRRHLPVFQHRRPDLYGN 321
>AL591806-16|CAI15379.1| 327|Homo sapiens nitrilase 1 protein.
Length = 327
Score = 59.7 bits (138), Expect = 2e-08
Identities = 60/207 (28%), Positives = 89/207 (42%), Gaps = 25/207 (12%)
Query: 169 RDEKHSDILWNTAVVISDTGNVIGKHRKNH-----IPRVGDFNESNYYMEGNTGHPVFAT 223
+D + + ++N V+++ G V+ +RK H IP G ESN M G + +T
Sbjct: 134 QDWEQTQKIYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVST 193
Query: 224 RYGKIAVNICFGRHHVLNWMMFGQNGAEIVFNPSATIAGEGGSEYMWNVEARNAAI-TNC 282
GKI + +C+ + Q GAEI+ PSA + G + W V R AI T C
Sbjct: 194 PAGKIGLAVCYDMRFPELSLALAQAGAEILTYPSAFGSITGPAH--WEVLLRARAIETQC 251
Query: 283 YFTAAINRVGYEEFPNEFTSADGKPAHKDLGLFYGSSYFCGPDGVRCPGLSRTRDGLLIA 342
Y AA + G+ H + YG S P G S GL +A
Sbjct: 252 YVVAA--------------AQCGR--HHEKRASYGHSMVVDPWGTVVARCSE-GPGLCLA 294
Query: 343 AVDLNLNRQIKDRRCYYMTQRLDMYVN 369
+DLN RQ++ + +R D+Y N
Sbjct: 295 RIDLNYLRQLRRHLPVFQHRRPDLYGN 321
>AF069987-1|AAC39907.1| 327|Homo sapiens nitrilase 1 protein.
Length = 327
Score = 59.7 bits (138), Expect = 2e-08
Identities = 60/207 (28%), Positives = 89/207 (42%), Gaps = 25/207 (12%)
Query: 169 RDEKHSDILWNTAVVISDTGNVIGKHRKNH-----IPRVGDFNESNYYMEGNTGHPVFAT 223
+D + + ++N V+++ G V+ +RK H IP G ESN M G + +T
Sbjct: 134 QDWEQTQKIYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVST 193
Query: 224 RYGKIAVNICFGRHHVLNWMMFGQNGAEIVFNPSATIAGEGGSEYMWNVEARNAAI-TNC 282
GKI + +C+ + Q GAEI+ PSA + G + W V R AI T C
Sbjct: 194 PAGKIGLAVCYDMRFPELSLALAQAGAEILTYPSAFGSITGPAH--WEVLLRARAIETQC 251
Query: 283 YFTAAINRVGYEEFPNEFTSADGKPAHKDLGLFYGSSYFCGPDGVRCPGLSRTRDGLLIA 342
Y AA + G+ H + YG S P G S GL +A
Sbjct: 252 YVVAA--------------AQCGR--HHEKRASYGHSMVVDPWGTVVARCSE-GPGLCLA 294
Query: 343 AVDLNLNRQIKDRRCYYMTQRLDMYVN 369
+DLN RQ++ + +R D+Y N
Sbjct: 295 RIDLNYLRQLRRHLPVFQHRRPDLYGN 321
>AF069984-1|AAC39901.1| 327|Homo sapiens nitrilase homolog 1
protein.
Length = 327
Score = 59.7 bits (138), Expect = 2e-08
Identities = 60/207 (28%), Positives = 89/207 (42%), Gaps = 25/207 (12%)
Query: 169 RDEKHSDILWNTAVVISDTGNVIGKHRKNH-----IPRVGDFNESNYYMEGNTGHPVFAT 223
+D + + ++N V+++ G V+ +RK H IP G ESN M G + +T
Sbjct: 134 QDWEQTQKIYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVST 193
Query: 224 RYGKIAVNICFGRHHVLNWMMFGQNGAEIVFNPSATIAGEGGSEYMWNVEARNAAI-TNC 282
GKI + +C+ + Q GAEI+ PSA + G + W V R AI T C
Sbjct: 194 PAGKIGLAVCYDMRFPELSLALAQAGAEILTYPSAFGSITGPAH--WEVLLRARAIETQC 251
Query: 283 YFTAAINRVGYEEFPNEFTSADGKPAHKDLGLFYGSSYFCGPDGVRCPGLSRTRDGLLIA 342
Y AA + G+ H + YG S P G S GL +A
Sbjct: 252 YVVAA--------------AQCGR--HHEKRASYGHSMVVDPWGTVVARCSE-GPGLCLA 294
Query: 343 AVDLNLNRQIKDRRCYYMTQRLDMYVN 369
+DLN RQ++ + +R D+Y N
Sbjct: 295 RIDLNYLRQLRRHLPVFQHRRPDLYGN 321
>BC020620-1|AAH20620.1| 276|Homo sapiens nitrilase family, member 2
protein.
Length = 276
Score = 54.4 bits (125), Expect = 7e-07
Identities = 58/272 (21%), Positives = 115/272 (42%), Gaps = 32/272 (11%)
Query: 107 AGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIKYAMVIVSSI 166
A +G I+ E +N P+ + + E+AE G +T L E+A + ++ ++
Sbjct: 31 AATQGAKIVSLPECFNSPYG-----AKYFPEYAEKIP-GESTQKLSEVAKECSIYLIGGS 84
Query: 167 LERDEKHSDILWNTAVVISDTGNVIGKHRKNH-----IPRVGDFNESNYYMEGNTGHPVF 221
+ E+ + L+NT V G ++ K+RK H +P F ES G++ F
Sbjct: 85 IP--EEDAGKLYNTCAVFGPDGTLLAKYRKIHLFDIDVPGKITFQESKTLSPGDS-FSTF 141
Query: 222 ATRYGKIAVNICFGRHHVLNWMMFGQNGAEIVFNPSATIAGEGGSEYMWNVEARNAAITN 281
T Y ++ + IC+ ++ Q G +++ P A G + W + R+ A+ N
Sbjct: 142 DTPYCRVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFNLTTGPAH--WELLQRSRAVDN 199
Query: 282 CYFTAAINRVGYEEFPNEFTSADGKPAHKDLGLFYGSSYFCGPDGVRCPGLSRTRDGLLI 341
+ A + + D K ++ + +G S P G + T + ++
Sbjct: 200 QVYVATAS-----------PARDDKASY----VAWGHSTVVNPWG-EALAKAGTEEAIVY 243
Query: 342 AAVDLNLNRQIKDRRCYYMTQRLDMYVNSLSK 373
+ +DL +I+ + + +R D+Y + K
Sbjct: 244 SDIDLKKLAEIRQQIPVFRQKRSDLYAVEMKK 275
>BC107890-1|AAI07891.1| 276|Homo sapiens nitrilase family, member 2
protein.
Length = 276
Score = 54.0 bits (124), Expect = 9e-07
Identities = 58/272 (21%), Positives = 115/272 (42%), Gaps = 32/272 (11%)
Query: 107 AGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIKYAMVIVSSI 166
A +G I+ E +N P+ + + E+AE G +T L E+A + ++ ++
Sbjct: 31 AATQGAKIVSLPECFNSPYG-----AKYFPEYAEKIP-GESTQKLSEVAKECSIYLIGGS 84
Query: 167 LERDEKHSDILWNTAVVISDTGNVIGKHRKNH-----IPRVGDFNESNYYMEGNTGHPVF 221
+ E+ + L+NT V G ++ K+RK H +P F ES G++ F
Sbjct: 85 IP--EEDAGKLYNTCAVFGPDGTLLAKYRKIHLFDIDVPGKITFQESKTLSPGDS-FSTF 141
Query: 222 ATRYGKIAVNICFGRHHVLNWMMFGQNGAEIVFNPSATIAGEGGSEYMWNVEARNAAITN 281
T Y ++ + IC+ ++ Q G +++ P A G + W + R+ A+ N
Sbjct: 142 DTPYCRVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFNLTTGPAH--WELLQRSRAVDN 199
Query: 282 CYFTAAINRVGYEEFPNEFTSADGKPAHKDLGLFYGSSYFCGPDGVRCPGLSRTRDGLLI 341
+ A + + D K ++ + +G S P G + T + ++
Sbjct: 200 QVYVATAS-----------PARDDKASY----VAWGHSTVVNPWG-EVLAKAGTEEAIVY 243
Query: 342 AAVDLNLNRQIKDRRCYYMTQRLDMYVNSLSK 373
+ +DL +I+ + + +R D+Y + K
Sbjct: 244 SDIDLKKLAEIRQQIPVFRQKRSDLYAVEMKK 275
>AF284574-1|AAF87103.1| 276|Homo sapiens Nit protein 2 protein.
Length = 276
Score = 54.0 bits (124), Expect = 9e-07
Identities = 58/272 (21%), Positives = 115/272 (42%), Gaps = 32/272 (11%)
Query: 107 AGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIKYAMVIVSSI 166
A +G I+ E +N P+ + + E+AE G +T L E+A + ++ ++
Sbjct: 31 AATQGAKIVSLPECFNSPYG-----AKYFPEYAEKIP-GESTQKLSEVAKECSIYLIGGS 84
Query: 167 LERDEKHSDILWNTAVVISDTGNVIGKHRKNH-----IPRVGDFNESNYYMEGNTGHPVF 221
+ E+ + L+NT V G ++ K+RK H +P F ES G++ F
Sbjct: 85 IP--EEDAGKLYNTCAVFGPDGTLLAKYRKIHLFDIDVPGKITFQESKTLSPGDS-FSTF 141
Query: 222 ATRYGKIAVNICFGRHHVLNWMMFGQNGAEIVFNPSATIAGEGGSEYMWNVEARNAAITN 281
T Y ++ + IC+ ++ Q G +++ P A G + W + R+ A+ N
Sbjct: 142 DTPYCRVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFNLTTGPAH--WELLQRSRAVDN 199
Query: 282 CYFTAAINRVGYEEFPNEFTSADGKPAHKDLGLFYGSSYFCGPDGVRCPGLSRTRDGLLI 341
+ A + + D K ++ + +G S P G + T + ++
Sbjct: 200 QVYVATAS-----------PARDDKASY----VAWGHSTVVNPWG-EVLAKAGTEEAIVY 243
Query: 342 AAVDLNLNRQIKDRRCYYMTQRLDMYVNSLSK 373
+ +DL +I+ + + +R D+Y + K
Sbjct: 244 SDIDLKKLAEIRQQIPVFRQKRSDLYAVEMKK 275
>AF260334-1|AAG44665.1| 276|Homo sapiens CUA002 protein.
Length = 276
Score = 54.0 bits (124), Expect = 9e-07
Identities = 58/272 (21%), Positives = 115/272 (42%), Gaps = 32/272 (11%)
Query: 107 AGQEGVNIICFQELWNMPFAFCTREKQPWCEFAESAEDGPTTTFLRELAIKYAMVIVSSI 166
A +G I+ E +N P+ + + E+AE G +T L E+A + ++ ++
Sbjct: 31 AATQGAKIVSLPECFNSPYG-----AKYFPEYAEKIP-GESTQKLSEVAKECSIYLIGGS 84
Query: 167 LERDEKHSDILWNTAVVISDTGNVIGKHRKNH-----IPRVGDFNESNYYMEGNTGHPVF 221
+ E+ + L+NT V G ++ K+RK H +P F ES G++ F
Sbjct: 85 IP--EEDAGKLYNTCAVFGPDGTLLAKYRKIHLFDIDVPGKITFQESKTLSPGDS-FSTF 141
Query: 222 ATRYGKIAVNICFGRHHVLNWMMFGQNGAEIVFNPSATIAGEGGSEYMWNVEARNAAITN 281
T Y ++ + IC+ ++ Q G +++ P A G + W + R+ A+ N
Sbjct: 142 DTPYCRVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFNLTTGPAH--WELLQRSRAVDN 199
Query: 282 CYFTAAINRVGYEEFPNEFTSADGKPAHKDLGLFYGSSYFCGPDGVRCPGLSRTRDGLLI 341
+ A + + D K ++ + +G S P G + T + ++
Sbjct: 200 QVYVATAS-----------PARDDKASY----VAWGHSTVVNPWG-EVLAKAGTEEAIVY 243
Query: 342 AAVDLNLNRQIKDRRCYYMTQRLDMYVNSLSK 373
+ +DL +I+ + + +R D+Y + K
Sbjct: 244 SDIDLKKLAEIRQQIPVFRQKRSDLYAVEMKK 275
>BC046149-1|AAH46149.1| 243|Homo sapiens NIT1 protein protein.
Length = 243
Score = 44.8 bits (101), Expect = 5e-04
Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 5/95 (5%)
Query: 169 RDEKHSDILWNTAVVISDTGNVIGKHRKNH-----IPRVGDFNESNYYMEGNTGHPVFAT 223
+D + + ++N V+++ G V+ +RK H IP G ESN M G + +T
Sbjct: 134 QDWEQTQKIYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVST 193
Query: 224 RYGKIAVNICFGRHHVLNWMMFGQNGAEIVFNPSA 258
GKI + +C+ + Q GAEI+ PSA
Sbjct: 194 PAGKIGLAVCYDMRFPELSLALAQAGAEILTYPSA 228
>AL591806-17|CAI15380.1| 243|Homo sapiens nitrilase 1 protein.
Length = 243
Score = 44.8 bits (101), Expect = 5e-04
Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 5/95 (5%)
Query: 169 RDEKHSDILWNTAVVISDTGNVIGKHRKNH-----IPRVGDFNESNYYMEGNTGHPVFAT 223
+D + + ++N V+++ G V+ +RK H IP G ESN M G + +T
Sbjct: 134 QDWEQTQKIYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVST 193
Query: 224 RYGKIAVNICFGRHHVLNWMMFGQNGAEIVFNPSA 258
GKI + +C+ + Q GAEI+ PSA
Sbjct: 194 PAGKIGLAVCYDMRFPELSLALAQAGAEILTYPSA 228
>X61972-1|CAA43964.1| 221|Homo sapiens macropain subunit iota
protein.
Length = 221
Score = 33.1 bits (72), Expect = 1.7
Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 1/65 (1%)
Query: 320 YFCGPDGVRCPGLSRTRDGLLIAAVDLNLNRQIKDRRCYYMTQRLDMYVNSLSKVLELDY 379
Y C P G C G T G+ L +++K + + Q ++ + LS VL +D+
Sbjct: 127 YKCDPAGYYC-GFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDF 185
Query: 380 KPQVV 384
KP +
Sbjct: 186 KPSEI 190
>X59417-1|CAA42052.1| 246|Homo sapiens prosomal P27K protein
protein.
Length = 246
Score = 33.1 bits (72), Expect = 1.7
Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 1/65 (1%)
Query: 320 YFCGPDGVRCPGLSRTRDGLLIAAVDLNLNRQIKDRRCYYMTQRLDMYVNSLSKVLELDY 379
Y C P G C G T G+ L +++K + + Q ++ + LS VL +D+
Sbjct: 152 YKCDPAGYYC-GFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDF 210
Query: 380 KPQVV 384
KP +
Sbjct: 211 KPSEI 215
>CR456944-1|CAG33225.1| 246|Homo sapiens PSMA6 protein.
Length = 246
Score = 33.1 bits (72), Expect = 1.7
Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 1/65 (1%)
Query: 320 YFCGPDGVRCPGLSRTRDGLLIAAVDLNLNRQIKDRRCYYMTQRLDMYVNSLSKVLELDY 379
Y C P G C G T G+ L +++K + + Q ++ + LS VL +D+
Sbjct: 152 YKCDPAGYYC-GFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDF 210
Query: 380 KPQVV 384
KP +
Sbjct: 211 KPSEI 215
>BC070137-1|AAH70137.1| 246|Homo sapiens proteasome (prosome,
macropain) subunit, alpha type, 6 protein.
Length = 246
Score = 33.1 bits (72), Expect = 1.7
Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 1/65 (1%)
Query: 320 YFCGPDGVRCPGLSRTRDGLLIAAVDLNLNRQIKDRRCYYMTQRLDMYVNSLSKVLELDY 379
Y C P G C G T G+ L +++K + + Q ++ + LS VL +D+
Sbjct: 152 YKCDPAGYYC-GFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDF 210
Query: 380 KPQVV 384
KP +
Sbjct: 211 KPSEI 215
>BC023659-1|AAH23659.1| 246|Homo sapiens proteasome (prosome,
macropain) subunit, alpha type, 6 protein.
Length = 246
Score = 33.1 bits (72), Expect = 1.7
Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 1/65 (1%)
Query: 320 YFCGPDGVRCPGLSRTRDGLLIAAVDLNLNRQIKDRRCYYMTQRLDMYVNSLSKVLELDY 379
Y C P G C G T G+ L +++K + + Q ++ + LS VL +D+
Sbjct: 152 YKCDPAGYYC-GFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDF 210
Query: 380 KPQVV 384
KP +
Sbjct: 211 KPSEI 215
>BC022354-1|AAH22354.1| 246|Homo sapiens proteasome (prosome,
macropain) subunit, alpha type, 6 protein.
Length = 246
Score = 33.1 bits (72), Expect = 1.7
Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 1/65 (1%)
Query: 320 YFCGPDGVRCPGLSRTRDGLLIAAVDLNLNRQIKDRRCYYMTQRLDMYVNSLSKVLELDY 379
Y C P G C G T G+ L +++K + + Q ++ + LS VL +D+
Sbjct: 152 YKCDPAGYYC-GFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDF 210
Query: 380 KPQVV 384
KP +
Sbjct: 211 KPSEI 215
>BC017882-1|AAH17882.1| 246|Homo sapiens proteasome (prosome,
macropain) subunit, alpha type, 6 protein.
Length = 246
Score = 33.1 bits (72), Expect = 1.7
Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 1/65 (1%)
Query: 320 YFCGPDGVRCPGLSRTRDGLLIAAVDLNLNRQIKDRRCYYMTQRLDMYVNSLSKVLELDY 379
Y C P G C G T G+ L +++K + + Q ++ + LS VL +D+
Sbjct: 152 YKCDPAGYYC-GFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDF 210
Query: 380 KPQVV 384
KP +
Sbjct: 211 KPSEI 215
>BC002979-1|AAH02979.1| 246|Homo sapiens proteasome (prosome,
macropain) subunit, alpha type, 6 protein.
Length = 246
Score = 33.1 bits (72), Expect = 1.7
Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 1/65 (1%)
Query: 320 YFCGPDGVRCPGLSRTRDGLLIAAVDLNLNRQIKDRRCYYMTQRLDMYVNSLSKVLELDY 379
Y C P G C G T G+ L +++K + + Q ++ + LS VL +D+
Sbjct: 152 YKCDPAGYYC-GFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDF 210
Query: 380 KPQVV 384
KP +
Sbjct: 211 KPSEI 215
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.136 0.416
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 57,517,323
Number of Sequences: 224733
Number of extensions: 2413894
Number of successful extensions: 3540
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 3501
Number of HSP's gapped (non-prelim): 38
length of query: 391
length of database: 73,234,838
effective HSP length: 91
effective length of query: 300
effective length of database: 52,784,135
effective search space: 15835240500
effective search space used: 15835240500
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 66 (30.7 bits)
- SilkBase 1999-2023 -