Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001587-TA|BGIBMGA001587-PA|IPR000533|Tropomyosin,
IPR009053|Prefoldin
(284 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M19713-1|AAA61225.1| 284|Homo sapiens TPM1 protein. 242 8e-64
AY640415-1|AAT68295.1| 284|Homo sapiens tropomyosin alpha stria... 242 1e-63
X06825-1|CAA29971.1| 284|Homo sapiens protein ( Human mRNA for ... 239 1e-62
AL133410-4|CAI10977.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 239 1e-62
X04201-1|CAA27798.1| 285|Homo sapiens protein ( Human skeletal ... 238 2e-62
BC008425-1|AAH08425.1| 285|Homo sapiens tropomyosin 3 protein. 238 2e-62
BC008407-1|AAH08407.1| 285|Homo sapiens tropomyosin 3 protein. 238 2e-62
AL590431-11|CAH71269.1| 284|Homo sapiens tropomyosin 3 protein. 238 2e-62
BC007433-1|AAH07433.1| 284|Homo sapiens tropomyosin 1 (alpha) p... 233 4e-61
AL133410-1|CAI10975.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 230 5e-60
AK023385-1|BAB14554.1| 284|Homo sapiens protein ( Homo sapiens ... 229 1e-59
AY640414-1|AAT68294.1| 284|Homo sapiens sarcomeric tropomyosin ... 226 6e-59
M19267-1|AAA36771.1| 284|Homo sapiens protein ( Human tropomyos... 225 1e-58
M75165-1|AAB59509.1| 284|Homo sapiens tropomyosin protein. 223 4e-58
M74817-1|AAA61230.1| 284|Homo sapiens tropomyosin-1 protein. 223 4e-58
M12125-1|AAA36773.1| 284|Homo sapiens protein ( Human fibroblas... 223 4e-58
BC011776-1|AAH11776.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 223 4e-58
AL133410-2|CAI10974.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 223 4e-58
AL133410-3|CAI10976.1| 322|Homo sapiens tropomyosin 2 (beta) pr... 222 1e-57
AK223258-1|BAD96978.1| 284|Homo sapiens tropomyosin 2 (beta) is... 221 2e-57
AF209746-1|AAF17621.1| 257|Homo sapiens beta tropomyosin protein. 214 3e-55
M19714-1|AAA61226.1| 264|Homo sapiens TPM1 protein. 210 6e-54
AK131384-1|BAD18535.1| 326|Homo sapiens protein ( Homo sapiens ... 205 2e-52
AL590431-12|CAH71270.1| 242|Homo sapiens tropomyosin 3 protein. 177 5e-44
AK092690-1|BAC03946.1| 243|Homo sapiens protein ( Homo sapiens ... 177 5e-44
BC053545-1|AAH53545.1| 245|Homo sapiens tropomyosin 1 (alpha) p... 176 6e-44
BC050473-1|AAH50473.1| 287|Homo sapiens TPM1 protein protein. 176 6e-44
AL590431-9|CAH71267.1| 248|Homo sapiens tropomyosin 3 protein. 176 8e-44
AL590431-10|CAH71268.1| 247|Homo sapiens tropomyosin 3 protein. 175 2e-43
AB209041-1|BAD92278.1| 303|Homo sapiens TPM1 protein variant pr... 173 4e-43
X05276-1|CAA28888.1| 248|Homo sapiens protein ( Human mRNA for ... 173 6e-43
BT019634-1|AAV38440.1| 248|Homo sapiens tropomyosin 4 protein. 173 6e-43
BC067225-1|AAH67225.1| 248|Homo sapiens tropomyosin 4 protein. 173 6e-43
BC037576-1|AAH37576.1| 248|Homo sapiens tropomyosin 4 protein. 173 6e-43
M19715-1|AAA61227.1| 229|Homo sapiens TPM1 protein. 173 8e-43
AL590431-5|CAH71266.1| 248|Homo sapiens tropomyosin 3 protein. 173 8e-43
AF474157-1|AAL84570.1| 247|Homo sapiens TPMsk3 protein. 173 8e-43
BC002827-1|AAH02827.1| 248|Homo sapiens tropomyosin 4 protein. 172 1e-42
AF474156-1|AAL84569.1| 203|Homo sapiens TPMsk1 protein. 171 2e-42
DQ424903-1|ABD83668.1| 245|Homo sapiens tropomyosin 1 alpha var... 167 4e-41
Z24727-1|CAA80853.1| 243|Homo sapiens tropomyosin isoform protein. 167 5e-41
X04588-1|CAB37185.1| 248|Homo sapiens protein ( Human 2.5 kb mR... 165 2e-40
BC072428-1|AAH72428.1| 248|Homo sapiens tropomyosin 3 protein. 165 2e-40
BC015403-1|AAH15403.1| 248|Homo sapiens tropomyosin 3 protein. 165 2e-40
BC000771-1|AAH00771.1| 248|Homo sapiens tropomyosin 3 protein. 165 2e-40
AL590431-7|CAH71264.1| 248|Homo sapiens tropomyosin 3 protein. 165 2e-40
AY004867-1|AAF87083.1| 247|Homo sapiens tropomyosin isoform pro... 163 5e-40
X12369-1|CAA30930.1| 227|Homo sapiens tropomyosin (227 AA) prot... 163 6e-40
AF310722-1|AAK17926.1| 320|Homo sapiens tropomyosin 4-anaplasti... 163 8e-40
AF186109-1|AAG17014.1| 237|Homo sapiens TPM4-ALK fusion oncopro... 163 8e-40
DQ120714-1|ABC40673.1| 247|Homo sapiens rcTPM3 protein. 158 2e-38
X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of t... 155 2e-37
AL590431-6|CAH71263.1| 224|Homo sapiens tropomyosin 3 protein. 135 2e-31
AK129882-1|BAC85248.1| 217|Homo sapiens protein ( Homo sapiens ... 134 3e-31
AL590431-8|CAH71265.1| 232|Homo sapiens tropomyosin 3 protein. 129 9e-30
BC062740-1|AAH62740.1| 158|Homo sapiens TPM3 protein protein. 125 2e-28
AL590431-4|CAH71262.1| 158|Homo sapiens tropomyosin 3 protein. 125 2e-28
AL590431-3|CAH71261.1| 158|Homo sapiens tropomyosin 3 protein. 117 4e-26
AF186110-1|AAG17015.1| 227|Homo sapiens TPM4-ALK fusion oncopro... 107 4e-23
AK092712-1|BAC03956.1| 183|Homo sapiens protein ( Homo sapiens ... 96 1e-19
M12126-1|AAA61229.1| 131|Homo sapiens TPM2 protein. 95 3e-19
M12127-1|AAA36774.1| 131|Homo sapiens protein ( Human cytoskele... 90 7e-18
D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heav... 77 9e-14
X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin he... 74 5e-13
BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,... 74 5e-13
BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,... 74 5e-13
BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein. 74 5e-13
AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin he... 74 5e-13
AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin he... 74 5e-13
AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY... 74 5e-13
AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein. 74 5e-13
BX537964-1|CAD97928.1| 898|Homo sapiens hypothetical protein pr... 74 7e-13
BC105632-1|AAI05633.1| 898|Homo sapiens chromosome 10 open read... 74 7e-13
BC103499-1|AAI03500.1| 898|Homo sapiens chromosome 10 open read... 74 7e-13
BC100670-1|AAI00671.1| 1004|Homo sapiens C10orf118 protein protein. 74 7e-13
AF273054-1|AAM44457.1| 613|Homo sapiens CTCL tumor antigen HD-C... 74 7e-13
AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin he... 73 2e-12
AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin he... 73 2e-12
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 70 8e-12
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 69 1e-11
AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated, coiled-... 69 1e-11
M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein. 68 3e-11
BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,... 68 3e-11
BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,... 68 3e-11
BC000280-1|AAH00280.1| 471|Homo sapiens MYH10 protein protein. 68 3e-11
AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein p... 68 3e-11
AF362887-1|AAK51964.1| 142|Homo sapiens tropomyosin 4-anaplasti... 67 8e-11
Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9, no... 66 1e-10
CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein. 66 1e-10
AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein pr... 66 1e-10
AK131080-1|BAC85130.1| 563|Homo sapiens FLJ00279 protein protein. 66 1e-10
AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy... 66 1e-10
M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle... 66 2e-10
X64838-1|CAA46050.1| 1427|Homo sapiens restin protein. 64 5e-10
S67238-1|AAB28950.1| 296|Homo sapiens smooth muscle myosin heav... 64 5e-10
M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protei... 64 5e-10
BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 64 5e-10
BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 64 5e-10
BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein. 64 5e-10
BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein. 64 5e-10
AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain prot... 64 5e-10
AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein. 64 5e-10
S67240-1|AAB28951.1| 330|Homo sapiens smooth muscle myosin heav... 63 9e-10
BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containi... 63 9e-10
D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heav... 63 1e-09
BC129821-1|AAI29822.1| 315|Homo sapiens FLJ36144 protein protein. 63 1e-09
S73840-1|AAC13916.1| 231|Homo sapiens type IIA myosin heavy cha... 62 2e-09
M25142-1|AAA60387.1| 389|Homo sapiens myosin heavy chain alpha-... 62 2e-09
BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2, ... 62 2e-09
AK097432-1|BAC05050.1| 466|Homo sapiens protein ( Homo sapiens ... 62 2e-09
AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa ... 62 2e-09
X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy... 62 2e-09
X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain (... 62 2e-09
X13939-1|CAA32122.1| 328|Homo sapiens laminin B2 protein. 62 2e-09
X06976-1|CAA30039.1| 543|Homo sapiens beta myosin heavy chain (... 62 2e-09
X03741-1|CAA27381.1| 635|Homo sapiens protein ( Human cardiac m... 62 2e-09
M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain p... 62 2e-09
M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain p... 62 2e-09
M55210-1|AAA59492.1| 1609|Homo sapiens laminin B2 chain protein. 62 2e-09
M27654-1|AAA59489.1| 217|Homo sapiens laminin B2 protein. 62 2e-09
M25139-1|AAA60385.1| 611|Homo sapiens myosin heavy chain beta-s... 62 2e-09
M21665-1|AAA36345.1| 524|Homo sapiens protein ( Human beta-myos... 62 2e-09
M17712-1|AAA36343.1| 543|Homo sapiens protein ( Human cardiac m... 62 2e-09
J03202-1|AAA59488.1| 1609|Homo sapiens LAMB2 protein. 62 2e-09
EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7, ... 62 2e-09
BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7, ... 62 2e-09
BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7, ... 62 2e-09
AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antige... 62 2e-09
AL450304-5|CAI14877.1| 1609|Homo sapiens laminin, gamma 1 (forme... 62 2e-09
AL354953-3|CAH70981.1| 1609|Homo sapiens laminin, gamma 1 (forme... 62 2e-09
AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain... 62 2e-09
AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypepti... 62 2e-09
Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein. 62 3e-09
X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal ... 62 3e-09
AK093463-1|BAC04173.1| 650|Homo sapiens protein ( Homo sapiens ... 62 3e-09
Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heav... 61 4e-09
X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein. 61 4e-09
U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein. 61 4e-09
U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein. 61 4e-09
DQ139275-1|ABA43896.1| 1313|Homo sapiens Tax1-binding protein 2 ... 61 4e-09
BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet coiled-... 61 4e-09
BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet coiled-... 61 4e-09
BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6, ... 61 4e-09
BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1, ... 61 4e-09
AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet coiled-... 61 4e-09
AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet coiled-... 61 4e-09
AF527734-1|AAP85633.1| 439|Homo sapiens medulloblastoma antigen... 61 4e-09
AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/... 61 4e-09
AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein. 61 4e-09
AB007914-1|BAA32290.2| 1919|Homo sapiens KIAA0445 protein protein. 61 4e-09
X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain ... 61 5e-09
BC118982-1|AAI18983.1| 553|Homo sapiens KIAA2012 protein protein. 61 5e-09
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 61 5e-09
AB095932-1|BAC23108.1| 555|Homo sapiens KIAA2012 protein protein. 61 5e-09
AB053469-1|BAC54108.1| 720|Homo sapiens ELKS gamma protein. 61 5e-09
AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein. 61 5e-09
AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein. 61 5e-09
AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein. 61 5e-09
BC127816-1|AAI27817.1| 416|Homo sapiens Unknown (protein for IM... 60 7e-09
AK092490-1|BAC03904.1| 280|Homo sapiens protein ( Homo sapiens ... 60 7e-09
X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy ch... 60 9e-09
X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mR... 60 9e-09
X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for ... 60 9e-09
X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 ... 60 9e-09
U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein. 60 9e-09
U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protei... 60 9e-09
M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy ch... 60 9e-09
BC101520-1|AAI01521.1| 1194|Homo sapiens protein tyrosine phosph... 60 9e-09
BC101518-1|AAI01519.1| 1194|Homo sapiens protein tyrosine phosph... 60 9e-09
AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical rhabdomyos... 60 9e-09
AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F, 3... 60 9e-09
AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F, 3... 60 9e-09
AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb ... 60 9e-09
AB014554-1|BAA31629.2| 1267|Homo sapiens KIAA0654 protein protein. 60 9e-09
AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens ... 60 1e-08
X03445-1|CAA27174.1| 572|Homo sapiens protein ( Human mRNA for ... 59 2e-08
X03444-1|CAA27173.1| 702|Homo sapiens protein ( Human mRNA for ... 59 2e-08
M21664-1|AAA36344.1| 532|Homo sapiens protein ( Human alpha-myo... 59 2e-08
M13451-1|AAA36164.1| 572|Homo sapiens protein ( Human lamin C m... 59 2e-08
BC014507-1|AAH14507.1| 664|Homo sapiens lamin A/C protein. 59 2e-08
BC003162-1|AAH03162.1| 572|Homo sapiens lamin A/C protein. 59 2e-08
BC000511-1|AAH00511.1| 572|Homo sapiens lamin A/C protein. 59 2e-08
AY847597-1|AAW32540.1| 664|Homo sapiens lamin A/C transcript va... 59 2e-08
AY847596-1|AAW32539.1| 480|Homo sapiens lamin A/C transcript va... 59 2e-08
AY528714-1|ABB04050.1| 487|Homo sapiens rhabdomyosarcoma antige... 59 2e-08
AY357727-1|AAR29466.1| 614|Homo sapiens progerin protein. 59 2e-08
AL135927-4|CAI15523.1| 614|Homo sapiens lamin A/C protein. 59 2e-08
AL135927-3|CAI15522.1| 664|Homo sapiens lamin A/C protein. 59 2e-08
AL135927-2|CAI15520.1| 465|Homo sapiens lamin A/C protein. 59 2e-08
AL135927-1|CAI15521.1| 572|Homo sapiens lamin A/C protein. 59 2e-08
AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein. 59 2e-08
X98801-1|CAA67333.1| 1263|Homo sapiens dynactin protein. 58 3e-08
X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein. 58 3e-08
L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated prote... 58 3e-08
BC071583-1|AAH71583.1| 1139|Homo sapiens DCTN1 protein protein. 58 3e-08
BC068006-1|AAH68006.1| 627|Homo sapiens ERC1 protein protein. 58 3e-08
AF086947-1|AAD03694.1| 1261|Homo sapiens dynactin 1 protein. 58 3e-08
AF064205-2|AAD55812.1| 1144|Homo sapiens dynactin 1 p135 isoform... 58 3e-08
AF064205-1|AAD55811.1| 1278|Homo sapiens dynactin 1 p150 isoform... 58 3e-08
AB209625-1|BAD92862.1| 459|Homo sapiens dynactin 1 isoform 1 va... 58 3e-08
Z97054-3|CAI42646.1| 1233|Homo sapiens structural maintenance of... 58 5e-08
S78271-1|AAB34405.1| 1233|Homo sapiens SB1.8/DXS423E protein. 58 5e-08
M12128-1|AAA36775.1| 96|Homo sapiens protein ( Human cytoskele... 58 5e-08
D80000-1|BAA11495.2| 1233|Homo sapiens KIAA0178 protein. 58 5e-08
BC112127-1|AAI12128.1| 1233|Homo sapiens SMC1 structural mainten... 58 5e-08
BC064368-1|AAH64368.1| 847|Homo sapiens SMC1A protein protein. 58 5e-08
AL161779-1|CAI42089.1| 1233|Homo sapiens structural maintenance ... 58 5e-08
Z29064-1|CAA82305.1| 896|Homo sapiens AF-1p protein. 57 6e-08
Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein. 57 6e-08
U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein. 57 6e-08
U07707-1|AAA52101.1| 896|Homo sapiens epidermal growth factor r... 57 6e-08
DQ367924-1|ABD34786.1| 896|Homo sapiens epidermal growth factor... 57 6e-08
BC033088-1|AAH33088.1| 465|Homo sapiens LMNA protein protein. 57 6e-08
AL671986-11|CAI13030.1| 896|Homo sapiens epidermal growth facto... 57 6e-08
AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein p... 57 6e-08
X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein. 57 8e-08
D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 prot... 57 8e-08
AF200415-1|AAF08305.2| 1825|Homo sapiens proliferation-related p... 57 8e-08
BC046212-1|AAH46212.1| 364|Homo sapiens Similar to cytomatrix p... 56 1e-07
AY847595-1|AAW32538.1| 664|Homo sapiens lamin A/C transcript va... 56 1e-07
AL138742-1|CAI22698.1| 1325|Homo sapiens KIAA1009 protein. 56 1e-07
AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golg... 56 1e-07
AB023226-1|BAA76853.2| 1345|Homo sapiens KIAA1009 protein protein. 56 1e-07
D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein. 56 1e-07
BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein. 56 1e-07
AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit S... 56 1e-07
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 56 1e-07
AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a varian... 56 1e-07
AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant... 56 1e-07
AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant... 56 1e-07
Z75311-1|CAA99729.1| 1318|Homo sapiens RAD50 homologue hsRAD50 p... 56 2e-07
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 56 2e-07
BC131590-1|AAI31591.1| 754|Homo sapiens EPS15L1 protein protein. 56 2e-07
BC104912-1|AAI04913.1| 1236|Homo sapiens PPFIA2 protein protein. 56 2e-07
BC020921-1|AAH20921.1| 560|Homo sapiens ITSN2 protein protein. 56 2e-07
AL832636-1|CAD89951.1| 546|Homo sapiens hypothetical protein pr... 56 2e-07
AF273047-1|AAG34907.1| 623|Homo sapiens CTCL tumor antigen se20... 56 2e-07
AF110265-1|AAF21930.1| 864|Homo sapiens epidermal growth factor... 56 2e-07
AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein. 56 2e-07
AB210009-1|BAE06091.1| 1258|Homo sapiens PPFIA2 variant protein ... 56 2e-07
AB015346-1|BAA88118.1| 864|Homo sapiens Eps15R protein. 56 2e-07
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 56 2e-07
X04627-1|CAA28300.1| 258|Homo sapiens beta-myosin heavy chain p... 55 2e-07
U80458-1|AAD00355.1| 1604|Homo sapiens microtubule associated pr... 55 2e-07
BC109126-1|AAI09127.1| 872|Homo sapiens chromosome 10 open read... 55 2e-07
BC036225-1|AAH36225.1| 872|Homo sapiens chromosome 10 open read... 55 2e-07
BC028423-1|AAH28423.1| 1022|Homo sapiens PMFBP1 protein protein. 55 2e-07
AL355378-1|CAI15667.1| 872|Homo sapiens novel protein protein. 55 2e-07
AL162742-5|CAI12110.1| 872|Homo sapiens novel protein protein. 55 2e-07
AK093285-1|BAC04121.1| 797|Homo sapiens protein ( Homo sapiens ... 55 2e-07
AK093227-1|BAC04102.1| 550|Homo sapiens protein ( Homo sapiens ... 55 2e-07
AF034799-1|AAC26100.1| 1257|Homo sapiens liprin-alpha2 protein. 55 2e-07
AB019987-1|BAA73535.1| 1288|Homo sapiens chromosome-associated p... 55 2e-07
BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein. 55 3e-07
BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein. 55 3e-07
BC101470-1|AAI01471.1| 1478|Homo sapiens FYVE and coiled-coil do... 55 3e-07
BC101468-1|AAI01469.1| 1478|Homo sapiens FYVE and coiled-coil do... 55 3e-07
BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein. 55 3e-07
AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein. 55 3e-07
AL365436-2|CAI16590.1| 1203|Homo sapiens cingulin protein. 55 3e-07
AL121586-4|CAB89415.1| 2442|Homo sapiens centrosomal protein 250... 55 3e-07
AJ292348-1|CAC33883.1| 1478|Homo sapiens FYVE and coiled-coil do... 55 3e-07
AF263462-1|AAF74498.1| 1203|Homo sapiens cingulin protein. 55 3e-07
AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associ... 55 3e-07
AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome assoc... 55 3e-07
AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein. 55 3e-07
AB037740-1|BAA92557.1| 1208|Homo sapiens KIAA1319 protein protein. 55 3e-07
U93121-1|AAB88727.1| 753|Homo sapiens M-phase phosphoprotein-1 ... 54 4e-07
BC129803-1|AAI29804.1| 638|Homo sapiens MYH14 protein protein. 54 4e-07
BC103824-1|AAI03825.1| 546|Homo sapiens taxilin alpha protein. 54 4e-07
BC103823-1|AAI03824.1| 546|Homo sapiens taxilin alpha protein. 54 4e-07
BC080578-1|AAH80578.1| 546|Homo sapiens taxilin alpha protein. 54 4e-07
BC050434-1|AAH50434.1| 273|Homo sapiens FLJ10154 protein protein. 54 4e-07
BC000676-1|AAH00676.2| 483|Homo sapiens MYH14 protein protein. 54 4e-07
AY739715-1|AAW65984.1| 617|Homo sapiens M-phase phosphoprotein ... 54 4e-07
AY359522-1|AAQ57128.1| 657|Homo sapiens hypothetical protein DK... 54 4e-07
AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein ... 54 4e-07
AY165122-1|AAO39147.1| 1995|Homo sapiens myosin heavy chain prot... 54 4e-07
AL834265-1|CAD38940.1| 505|Homo sapiens hypothetical protein pr... 54 4e-07
AL833308-1|CAD89924.1| 878|Homo sapiens hypothetical protein pr... 54 4e-07
AL445928-1|CAH72248.1| 657|Homo sapiens novel protein protein. 54 4e-07
AL442127-3|CAI13168.1| 273|Homo sapiens RP11-297I6.1 protein. 54 4e-07
AL157400-6|CAI16830.1| 1820|Homo sapiens M-phase phosphoprotein ... 54 4e-07
AL157400-5|CAI16831.1| 1780|Homo sapiens M-phase phosphoprotein ... 54 4e-07
AL157389-3|CAI12887.1| 1780|Homo sapiens M-phase phosphoprotein ... 54 4e-07
AL157389-2|CAI12886.1| 1820|Homo sapiens M-phase phosphoprotein ... 54 4e-07
AL049795-2|CAI22055.1| 546|Homo sapiens novel protein protein. 54 4e-07
AK024959-1|BAB15043.1| 696|Homo sapiens protein ( Homo sapiens ... 54 4e-07
AK023943-1|BAB14735.1| 545|Homo sapiens protein ( Homo sapiens ... 54 4e-07
AK001016-1|BAA91467.1| 273|Homo sapiens protein ( Homo sapiens ... 54 4e-07
AF516206-1|AAO42465.1| 546|Homo sapiens taxilin protein. 54 4e-07
AB111886-1|BAC98374.1| 1571|Homo sapiens KIAA2034 protein protein. 54 4e-07
AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related... 54 4e-07
U22816-1|AAC50173.1| 1202|Homo sapiens LAR-interacting protein 1... 54 6e-07
U22815-1|AAC50172.1| 1185|Homo sapiens LAR-interacting protein 1... 54 6e-07
BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein. 54 6e-07
BC101026-1|AAI01027.1| 490|Homo sapiens SASS6 protein protein. 54 6e-07
BC034046-1|AAH34046.1| 1202|Homo sapiens protein tyrosine phosph... 54 6e-07
AK022532-1|BAB14081.1| 975|Homo sapiens protein ( Homo sapiens ... 54 6e-07
AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein. 54 6e-07
AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein... 54 6e-07
BC007808-1|AAH07808.1| 1006|Homo sapiens MYH7B protein protein. 54 8e-07
AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,... 54 8e-07
AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,... 54 8e-07
AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein. 54 8e-07
U63139-1|AAB07119.1| 1312|Homo sapiens Rad50 protein. 53 1e-06
M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy cha... 53 1e-06
L02320-1|AAA36541.1| 583|Homo sapiens radixin protein. 53 1e-06
BC091490-1|AAH91490.1| 620|Homo sapiens ODF2L protein protein. 53 1e-06
BC060769-1|AAH60769.2| 1107|Homo sapiens chromosome 6 open readi... 53 1e-06
BC049849-1|AAH49849.1| 1374|Homo sapiens Unknown (protein for IM... 53 1e-06
BC013023-1|AAH13023.1| 1193|Homo sapiens NUMA1 protein protein. 53 1e-06
AY014284-1|AAK27309.1| 699|Homo sapiens nucleoporin NYD-SP7 pro... 53 1e-06
AL365275-1|CAI40383.1| 1140|Homo sapiens chromosome 6 open readi... 53 1e-06
AL137009-1|CAI20344.1| 1140|Homo sapiens chromosome 6 open readi... 53 1e-06
AL132874-2|CAI42604.1| 1140|Homo sapiens chromosome 6 open readi... 53 1e-06
AL031283-6|CAI21428.1| 692|Homo sapiens forkhead-associated (FH... 53 1e-06
AK131470-1|BAD18615.1| 458|Homo sapiens protein ( Homo sapiens ... 53 1e-06
AK091682-1|BAC03719.1| 936|Homo sapiens protein ( Homo sapiens ... 53 1e-06
AF057300-1|AAD50326.1| 1173|Homo sapiens truncated RAD50 protein... 53 1e-06
AF057299-1|AAD50325.1| 1312|Homo sapiens RAD50-2 protein protein. 53 1e-06
AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein. 53 1e-06
AB067524-1|BAB67830.1| 704|Homo sapiens KIAA1937 protein protein. 53 1e-06
AB033102-1|BAA86590.1| 1068|Homo sapiens KIAA1276 protein protein. 53 1e-06
AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein. 53 1e-06
Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein. 53 1e-06
X58677-1|CAA41528.1| 608|Homo sapiens hemidesmosomal plaque pr... 53 1e-06
U51587-1|AAB81549.1| 767|Homo sapiens Golgi complex autoantigen... 53 1e-06
U38292-1|AAB41133.1| 2805|Homo sapiens microtubule-associated pr... 53 1e-06
U38291-1|AAB41132.1| 2805|Homo sapiens microtubule-associated pr... 53 1e-06
M61951-1|AAA59486.1| 1786|Homo sapiens laminin B1 protein. 53 1e-06
M61916-1|AAA59482.1| 1786|Homo sapiens laminin B1 protein. 53 1e-06
M55370-1|AAA59485.1| 1786|Homo sapiens laminin B1 protein. 53 1e-06
BC113455-1|AAI13456.1| 1786|Homo sapiens laminin, beta 1 protein. 53 1e-06
BC092419-1|AAH92419.1| 701|Homo sapiens hypothetical LOC550631 ... 53 1e-06
BC039828-1|AAH39828.1| 1091|Homo sapiens structural maintenance ... 53 1e-06
BC032853-1|AAH32853.1| 767|Homo sapiens golgi autoantigen, golg... 53 1e-06
BC026018-1|AAH26018.2| 1083|Homo sapiens LAMB1 protein protein. 53 1e-06
AJ310551-1|CAC39248.1| 1091|Homo sapiens SMC6 protein protein. 53 1e-06
AF265230-1|AAK58539.1| 975|Homo sapiens RING finger protein 20 ... 53 1e-06
AF092564-1|AAC72361.1| 1202|Homo sapiens chromosome-associated p... 53 1e-06
AC097377-2|AAX88851.1| 1091|Homo sapiens unknown protein. 53 1e-06
AC002563-2|AAB71327.1| 1286|Homo sapiens WUGSC:H_127H14.1 protein. 53 1e-06
AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein p... 53 1e-06
AB208858-1|BAD92095.1| 400|Homo sapiens golgin 97 variant protein. 53 1e-06
AB208841-1|BAD92078.1| 1585|Homo sapiens Nuclear mitotic apparat... 53 1e-06
AB023166-1|BAA76793.2| 1559|Homo sapiens KIAA0949 protein protein. 53 1e-06
Z98946-1|CAB46379.1| 577|Homo sapiens moesin protein. 52 2e-06
Z22551-1|CAA80271.1| 1356|Homo sapiens 156 kDa Protein protein. 52 2e-06
S67247-1|AAB28952.1| 226|Homo sapiens smooth muscle myosin heav... 52 2e-06
M69066-1|AAA36322.1| 577|Homo sapiens moesin B protein. 52 2e-06
L25616-1|AAB65853.1| 1300|Homo sapiens kinectin protein. 52 2e-06
D13629-1|BAA02794.2| 1307|Homo sapiens KIAA0004 protein. 52 2e-06
BX538186-1|CAD98058.1| 971|Homo sapiens hypothetical protein pr... 52 2e-06
BC117132-1|AAI17133.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 52 2e-06
BC112337-1|AAI12338.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 52 2e-06
BC110585-1|AAI10586.1| 975|Homo sapiens ring finger protein 20 ... 52 2e-06
BC110584-1|AAI10585.1| 975|Homo sapiens ring finger protein 20 ... 52 2e-06
BC050555-1|AAH50555.1| 873|Homo sapiens KTN1 protein protein. 52 2e-06
BC017293-1|AAH17293.1| 577|Homo sapiens moesin protein. 52 2e-06
BC008345-1|AAH08345.1| 963|Homo sapiens Unknown (protein for IM... 52 2e-06
AY264265-1|AAP20418.1| 1357|Homo sapiens kinectin variant 1 prot... 52 2e-06
AY176045-1|AAO46889.1| 1299|Homo sapiens Grb10 interacting GYF p... 52 2e-06
AL591377-3|CAH69963.1| 977|Homo sapiens ring finger protein 20 ... 52 2e-06
AL451125-2|CAI14346.1| 767|Homo sapiens golgi autoantigen, golg... 52 2e-06
AL451082-2|CAH72276.1| 1194|Homo sapiens protein tyrosine phosph... 52 2e-06
AL354928-1|CAI39632.1| 767|Homo sapiens golgi autoantigen, golg... 52 2e-06
AL353621-9|CAI14618.1| 977|Homo sapiens ring finger protein 20 ... 52 2e-06
AK022300-1|BAB14005.1| 746|Homo sapiens protein ( Homo sapiens ... 52 2e-06
AK001739-1|BAA91873.1| 1100|Homo sapiens protein ( Homo sapiens ... 52 2e-06
AF083322-1|AAC32373.1| 994|Homo sapiens centriole associated pr... 52 2e-06
AB014542-1|BAA31617.2| 1329|Homo sapiens KIAA0642 protein protein. 52 2e-06
Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein. 52 2e-06
X66397-1|CAA47021.1| 2349|Homo sapiens Tpr protein. 52 2e-06
U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein. 52 2e-06
AY536375-1|AAT66048.1| 820|Homo sapiens rhabdomyosarcoma antige... 52 2e-06
AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter r... 52 2e-06
AL137068-7|CAD20123.1| 1007|Homo sapiens centrosomal protein 110... 52 2e-06
AL137068-5|CAI12358.1| 1773|Homo sapiens centrosomal protein 110... 52 2e-06
AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110... 52 2e-06
AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter r... 52 2e-06
AK092201-1|BAC03827.1| 284|Homo sapiens protein ( Homo sapiens ... 52 2e-06
AK074079-1|BAB84905.1| 1793|Homo sapiens FLJ00150 protein protein. 52 2e-06
AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein. 52 2e-06
L01042-1|AAD54608.1| 1093|Homo sapiens TATA element modulatory f... 52 3e-06
BX538286-1|CAD98081.1| 724|Homo sapiens hypothetical protein pr... 52 3e-06
BC126123-1|AAI26124.1| 1093|Homo sapiens TATA element modulatory... 52 3e-06
BC117418-1|AAI17419.1| 1093|Homo sapiens TATA element modulatory... 52 3e-06
BC112391-1|AAI12392.1| 957|Homo sapiens ELKS/RAB6-interacting/C... 52 3e-06
BC111550-1|AAI11551.1| 957|Homo sapiens ERC2 protein protein. 52 3e-06
BC047109-1|AAH47109.1| 583|Homo sapiens radixin protein. 52 3e-06
BC000616-1|AAH00616.1| 585|Homo sapiens SWAP-70 protein protein. 52 3e-06
AY651261-1|AAX35689.1| 1244|Homo sapiens centrosomal protein 1 p... 52 3e-06
AL139421-4|CAI22511.1| 720|Homo sapiens coiled-coil domain cont... 52 3e-06
AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain cont... 52 3e-06
AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain cont... 52 3e-06
AL137068-6|CAI12359.1| 346|Homo sapiens centrosomal protein 110... 52 3e-06
AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens ... 52 3e-06
AF210818-1|AAF24486.1| 585|Homo sapiens SWAP-70 protein. 52 3e-06
AF134894-1|AAF61403.1| 585|Homo sapiens SWAP-70 homolog protein. 52 3e-06
AB209109-1|BAD92346.1| 1096|Homo sapiens TATA element modulatory... 52 3e-06
AB014540-1|BAA31615.1| 603|Homo sapiens KIAA0640 protein protein. 52 3e-06
AB002376-1|BAA20832.2| 970|Homo sapiens KIAA0378 protein. 52 3e-06
BC016175-1|AAH16175.1| 279|Homo sapiens Unknown (protein for IM... 51 4e-06
BC006984-1|AAH06984.1| 512|Homo sapiens Unknown (protein for IM... 51 4e-06
AL832637-1|CAD89952.1| 546|Homo sapiens hypothetical protein pr... 51 4e-06
AK126045-1|BAC86410.1| 978|Homo sapiens galactosaminyltransfera... 51 4e-06
AK027881-1|BAB55428.1| 690|Homo sapiens protein ( Homo sapiens ... 51 4e-06
AK027705-1|BAB55310.1| 965|Homo sapiens protein ( Homo sapiens ... 51 4e-06
M63618-1|AAA35606.1| 2095|Homo sapiens bullous pemphigoid antige... 51 5e-06
L11690-1|AAA52288.1| 2649|Homo sapiens bullous pemphigoid antige... 51 5e-06
BC141866-1|AAI41867.1| 1240|Homo sapiens Unknown (protein for IM... 51 5e-06
BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein. 51 5e-06
AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein. 51 5e-06
AL096710-6|CAI22047.1| 2649|Homo sapiens dystonin protein. 51 5e-06
AK124118-1|BAC85777.1| 157|Homo sapiens protein ( Homo sapiens ... 51 5e-06
AB028997-1|BAA83026.2| 1715|Homo sapiens KIAA1074 protein protein. 51 5e-06
Z22664-1|CAA80377.1| 595|Homo sapiens membrane organizing prote... 50 7e-06
Y18000-2|CAA76993.1| 615|Homo sapiens NF2 protein protein. 50 7e-06
Y18000-1|CAA76992.1| 595|Homo sapiens NF2 protein protein. 50 7e-06
X72655-1|CAA51220.1| 595|Homo sapiens schwannomin protein. 50 7e-06
X65873-1|CAA46703.1| 963|Homo sapiens kinesin heavy chain protein. 50 7e-06
U29343-1|AAC52049.1| 725|Homo sapiens hyaluronan receptor protein. 50 7e-06
L11353-1|AAA36212.1| 595|Homo sapiens moesin-ezrin-radixin-like... 50 7e-06
CR456530-1|CAG30416.1| 595|Homo sapiens NF2 protein. 50 7e-06
BC126281-1|AAI26282.1| 963|Homo sapiens kinesin family member 5... 50 7e-06
BC126279-1|AAI26280.1| 963|Homo sapiens kinesin family member 5... 50 7e-06
BC020257-1|AAH20257.1| 595|Homo sapiens neurofibromin 2 (bilate... 50 7e-06
BC003112-1|AAH03112.2| 507|Homo sapiens neurofibromin 2 (bilate... 50 7e-06
AL161932-2|CAH71618.1| 963|Homo sapiens kinesin family member 5... 50 7e-06
AL021391-1|CAI18928.1| 1235|Homo sapiens structural maintenance ... 50 7e-06
AL008718-2|CAI17945.1| 1235|Homo sapiens structural maintenance ... 50 7e-06
AK128577-1|BAC87508.1| 1080|Homo sapiens protein ( Homo sapiens ... 50 7e-06
AK025690-1|BAB15219.1| 746|Homo sapiens protein ( Homo sapiens ... 50 7e-06
AJ504806-1|CAD43404.2| 1235|Homo sapiens SMC1beta protein protein. 50 7e-06
AF543495-1|AAN40505.1| 453|Homo sapiens melanoma-associated ant... 50 7e-06
AF432208-1|AAL99915.1| 187|Homo sapiens CLL-associated antigen ... 50 7e-06
AF369701-1|AAK54196.1| 590|Homo sapiens neurofibromatosis type ... 50 7e-06
AF369665-1|AAK54166.1| 507|Homo sapiens neurofibromatosis type ... 50 7e-06
AF369664-1|AAK54165.1| 549|Homo sapiens neurofibromatosis type ... 50 7e-06
AF369663-1|AAK54164.1| 548|Homo sapiens neurofibromatosis type ... 50 7e-06
AF369662-1|AAK54163.1| 590|Homo sapiens neurofibromatosis type ... 50 7e-06
AF369661-1|AAK54162.1| 595|Homo sapiens neurofibromatosis type ... 50 7e-06
AF369658-1|AAK54161.1| 590|Homo sapiens neurofibromatosis type ... 50 7e-06
AF369657-1|AAK54160.1| 595|Homo sapiens neurofibromatosis type ... 50 7e-06
Z99496-1|CAI21605.1| 805|Homo sapiens chromosome 6 open reading... 50 9e-06
BC127760-1|AAI27761.1| 658|Homo sapiens Unknown (protein for IM... 50 9e-06
BC126208-1|AAI26209.1| 1161|Homo sapiens SMC1B protein protein. 50 9e-06
BC078168-1|AAH78168.1| 887|Homo sapiens KIAA1212 protein protein. 50 9e-06
BC029425-1|AAH29425.1| 272|Homo sapiens Unknown (protein for IM... 50 9e-06
BC003177-1|AAH03177.1| 691|Homo sapiens calcium binding and coi... 50 9e-06
BC002932-1|AAH02932.1| 850|Homo sapiens CEP110 protein protein. 50 9e-06
AY563137-1|AAT68474.1| 691|Homo sapiens calphoglin protein. 50 9e-06
AY358397-1|AAQ88763.1| 691|Homo sapiens EESP2436 protein. 50 9e-06
AL832009-1|CAD89912.1| 1177|Homo sapiens hypothetical protein pr... 50 9e-06
AL589993-1|CAI16048.1| 805|Homo sapiens chromosome 6 open readi... 50 9e-06
AL589986-1|CAH70024.1| 1943|Homo sapiens trichohyalin protein. 50 9e-06
AL390069-1|CAI14134.1| 805|Homo sapiens chromosome 6 open readi... 50 9e-06
AL137068-4|CAI12357.1| 994|Homo sapiens centrosomal protein 110... 50 9e-06
AL137068-3|CAI12356.1| 828|Homo sapiens centrosomal protein 110... 50 9e-06
AK128098-1|BAC87273.1| 1185|Homo sapiens protein ( Homo sapiens ... 50 9e-06
AF308284-1|AAG48252.1| 546|Homo sapiens serologically defined b... 50 9e-06
AB040969-1|BAA96060.1| 645|Homo sapiens KIAA1536 protein protein. 50 9e-06
X97053-1|CAA65765.1| 566|Homo sapiens plectin protein. 50 1e-05
U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein. 50 1e-05
U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein. 50 1e-05
M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein. 50 1e-05
J05211-1|AAA35766.1| 1752|Homo sapiens protein ( Human desmoplak... 50 1e-05
D63997-1|BAA23661.1| 1530|Homo sapiens GCP170 protein. 50 1e-05
DQ679757-1|ABG74698.1| 1215|Homo sapiens intersectin 1 short for... 50 1e-05
DQ679756-1|ABG74697.1| 1178|Homo sapiens intersectin 1 short for... 50 1e-05
DQ679755-1|ABG74696.1| 1149|Homo sapiens intersectin 1 short for... 50 1e-05
DQ679754-1|ABG74695.1| 1144|Homo sapiens intersectin 1 short for... 50 1e-05
DQ386455-1|ABD72328.1| 1020|Homo sapiens intersectin 1 short for... 50 1e-05
DQ340865-1|ABC69037.1| 1076|Homo sapiens intersectin 1 short for... 50 1e-05
CR533567-1|CAG38598.1| 691|Homo sapiens KIAA1536 protein. 50 1e-05
BX538175-1|CAD98050.1| 627|Homo sapiens hypothetical protein pr... 50 1e-05
BC131515-1|AAI31516.1| 632|Homo sapiens GOLGA6 protein protein. 50 1e-05
BC128578-1|AAI28579.1| 751|Homo sapiens RRBP1 protein protein. 50 1e-05
BC128577-1|AAI28578.1| 934|Homo sapiens RRBP1 protein protein. 50 1e-05
BC126912-1|AAI26913.1| 1132|Homo sapiens CROCC protein protein. 50 1e-05
BC126911-1|AAI26912.1| 1132|Homo sapiens CROCC protein protein. 50 1e-05
BC117560-1|AAI17561.1| 1144|Homo sapiens ITSN1 protein protein. 50 1e-05
BC116186-1|AAI16187.1| 1721|Homo sapiens intersectin 1 (SH3 doma... 50 1e-05
BC116185-1|AAI16186.1| 1716|Homo sapiens ITSN1 protein protein. 50 1e-05
BC114620-1|AAI14621.1| 1756|Homo sapiens periplakin protein. 50 1e-05
BC108904-1|AAI08905.1| 725|Homo sapiens hyaluronan-mediated mot... 50 1e-05
BC073744-1|AAH73744.1| 648|Homo sapiens ITSN1 protein protein. 50 1e-05
BC070281-1|AAH70281.1| 552|Homo sapiens HMMR protein protein. 50 1e-05
BC060826-1|AAH60826.1| 843|Homo sapiens GOLGA3 protein protein. 50 1e-05
BC058925-1|AAH58925.1| 634|Homo sapiens ITSN1 protein protein. 50 1e-05
BC057227-1|AAH57227.1| 318|Homo sapiens Unknown (protein for IM... 50 1e-05
BC054492-1|AAH54492.1| 997|Homo sapiens RABGAP1 protein protein. 50 1e-05
BC040232-1|AAH40232.1| 696|Homo sapiens CCDC88 protein protein. 50 1e-05
AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein. 50 1e-05
AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein. 50 1e-05
AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein. 50 1e-05
AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein. 50 1e-05
AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein. 50 1e-05
AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein. 50 1e-05
>M19713-1|AAA61225.1| 284|Homo sapiens TPM1 protein.
Length = 284
Score = 242 bits (593), Expect = 8e-64
Identities = 123/281 (43%), Positives = 187/281 (66%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
MDAIKKKMQ +KL+K+NA+D+A+ E + A R++++ +E+ LQKKL E++L
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
DE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+R + + K +ELEEELK V N+LKSLE EK +Q+ + +
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LEDEL K +YK++++E+D ++
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDM 281
Score = 69.7 bits (163), Expect = 1e-11
Identities = 45/205 (21%), Positives = 105/205 (51%), Gaps = 7/205 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + + +
Sbjct: 87 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEI 146
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 147 QLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEEELKT 199
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++ ED
Sbjct: 200 VTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDE 259
Query: 183 VKSGDAKISELEEELKVVGNSLKSL 207
+ + K + EEL N + S+
Sbjct: 260 LYAQKLKYKAISEELDHALNDMTSI 284
Score = 32.3 bits (70), Expect = 2.0
Identities = 14/80 (17%), Positives = 40/80 (50%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +++ + + ++D ++ + ++A RAE V +L+K + +E++L
Sbjct: 204 LKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQ 263
Query: 61 KNKLEQANKDLEEKEKQLTA 80
K K + +++L+ +T+
Sbjct: 264 KLKYKAISEELDHALNDMTS 283
>AY640415-1|AAT68295.1| 284|Homo sapiens tropomyosin alpha striated
muscle isoform protein.
Length = 284
Score = 242 bits (592), Expect = 1e-63
Identities = 123/281 (43%), Positives = 186/281 (66%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
MDAIKKKMQ +KL+K+NA+D+A+ E + A R++++ +E+ LQKKL E++L
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
DE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+R + + K +ELEEELK V N LKSLE EK +Q+ + +
Sbjct: 181 ERAELSEGKCAELEEELKTVTNDLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LEDEL K +YK++++E+D ++
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDM 281
Score = 69.3 bits (162), Expect = 1e-11
Identities = 45/205 (21%), Positives = 105/205 (51%), Gaps = 7/205 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + + +
Sbjct: 87 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEI 146
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 147 QLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEEELKT 199
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++ ED
Sbjct: 200 VTNDLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDE 259
Query: 183 VKSGDAKISELEEELKVVGNSLKSL 207
+ + K + EEL N + S+
Sbjct: 260 LYAQKLKYKAISEELDHALNDMTSI 284
Score = 32.3 bits (70), Expect = 2.0
Identities = 14/80 (17%), Positives = 40/80 (50%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +++ + + ++D ++ + ++A RAE V +L+K + +E++L
Sbjct: 204 LKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQ 263
Query: 61 KNKLEQANKDLEEKEKQLTA 80
K K + +++L+ +T+
Sbjct: 264 KLKYKAISEELDHALNDMTS 283
>X06825-1|CAA29971.1| 284|Homo sapiens protein ( Human mRNA for
skeletal beta-tropomyosin. ).
Length = 284
Score = 239 bits (584), Expect = 1e-62
Identities = 117/281 (41%), Positives = 189/281 (67%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+R + ++K +LEEELK+V N+LKSLE +K + + +++
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LEDE+ K +YK++++E+D+ ++
Sbjct: 241 FAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDI 281
Score = 70.1 bits (164), Expect = 8e-12
Identities = 48/205 (23%), Positives = 104/205 (50%), Gaps = 7/205 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + L +
Sbjct: 87 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEM 146
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L++A E+ +++ EVA RK+ +E +LE+SEER+ A+ K + ++
Sbjct: 147 QLKEAKHIAEDSDRKYE----EVA---RKLVILEGELERSEERAEVAESKCGDLEEELKI 199
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
K LE +A + + D+ ++K ++A+ +++ R +A +E ++ ED
Sbjct: 200 VTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDE 259
Query: 183 VKSGDAKISELEEELKVVGNSLKSL 207
V + K + EEL N + SL
Sbjct: 260 VYAQKMKYKAISEELDNALNDITSL 284
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/80 (17%), Positives = 41/80 (51%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +++ + ++D ++ E++ ++A RAE V +L+K + +E+++
Sbjct: 204 LKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQ 263
Query: 61 KNKLEQANKDLEEKEKQLTA 80
K K + +++L+ +T+
Sbjct: 264 KMKYKAISEELDNALNDITS 283
>AL133410-4|CAI10977.1| 284|Homo sapiens tropomyosin 2 (beta)
protein.
Length = 284
Score = 239 bits (584), Expect = 1e-62
Identities = 117/281 (41%), Positives = 189/281 (67%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+R + ++K +LEEELK+V N+LKSLE +K + + +++
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LEDE+ K +YK++++E+D+ ++
Sbjct: 241 FAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDI 281
Score = 70.1 bits (164), Expect = 8e-12
Identities = 48/205 (23%), Positives = 104/205 (50%), Gaps = 7/205 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + L +
Sbjct: 87 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEM 146
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L++A E+ +++ EVA RK+ +E +LE+SEER+ A+ K + ++
Sbjct: 147 QLKEAKHIAEDSDRKYE----EVA---RKLVILEGELERSEERAEVAESKCGDLEEELKI 199
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
K LE +A + + D+ ++K ++A+ +++ R +A +E ++ ED
Sbjct: 200 VTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDE 259
Query: 183 VKSGDAKISELEEELKVVGNSLKSL 207
V + K + EEL N + SL
Sbjct: 260 VYAQKMKYKAISEELDNALNDITSL 284
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/80 (17%), Positives = 41/80 (51%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +++ + ++D ++ E++ ++A RAE V +L+K + +E+++
Sbjct: 204 LKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQ 263
Query: 61 KNKLEQANKDLEEKEKQLTA 80
K K + +++L+ +T+
Sbjct: 264 KMKYKAISEELDNALNDITS 283
>X04201-1|CAA27798.1| 285|Homo sapiens protein ( Human skeletal
muscle 1.3 kb mRNA for tropomyosin. ).
Length = 285
Score = 238 bits (582), Expect = 2e-62
Identities = 120/281 (42%), Positives = 187/281 (66%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M+AIKKKMQ +KL+K+NA+D+A+ E + + A R++++ +E+ +QKKL E++L
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
L+ A + LE EK+ EAEVA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E
Sbjct: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+R + ++K SELEEELK V N+LKSLE EK +Q+ +++
Sbjct: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LEDEL K +YK++++E+D ++
Sbjct: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDM 282
Score = 73.7 bits (173), Expect = 7e-13
Identities = 49/205 (23%), Positives = 106/205 (51%), Gaps = 7/205 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + L +
Sbjct: 88 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEI 147
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L++A EE +++ EVA RK+ IE DLE++EER+ A+ K E ++
Sbjct: 148 QLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESKCSELEEELKN 200
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
K LE +A++ ++ D+ ++K ++A+ +++ R +A +E ++ ED
Sbjct: 201 VTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDE 260
Query: 183 VKSGDAKISELEEELKVVGNSLKSL 207
+ + K + EEL N + S+
Sbjct: 261 LYAQKLKYKAISEELDHALNDMTSI 285
Score = 31.1 bits (67), Expect = 4.6
Identities = 15/94 (15%), Positives = 45/94 (47%)
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
M + ++ + Q + + ++ ++A + A+ +S ++ +LA ++ +L+ ED +
Sbjct: 1 MMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDK 60
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ + +E+L++ E N+R++
Sbjct: 61 YSEALKDAQEKLELAEKKAADAEAEVASLNRRIQ 94
Score = 31.1 bits (67), Expect = 4.6
Identities = 14/80 (17%), Positives = 40/80 (50%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +++ + + ++D ++ + ++A RAE V +L+K + +E++L
Sbjct: 205 LKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQ 264
Query: 61 KNKLEQANKDLEEKEKQLTA 80
K K + +++L+ +T+
Sbjct: 265 KLKYKAISEELDHALNDMTS 284
>BC008425-1|AAH08425.1| 285|Homo sapiens tropomyosin 3 protein.
Length = 285
Score = 238 bits (582), Expect = 2e-62
Identities = 120/281 (42%), Positives = 187/281 (66%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M+AIKKKMQ +KL+K+NA+D+A+ E + + A R++++ +E+ +QKKL E++L
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
L+ A + LE EK+ EAEVA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E
Sbjct: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+R + ++K SELEEELK V N+LKSLE EK +Q+ +++
Sbjct: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LEDEL K +YK++++E+D ++
Sbjct: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDM 282
Score = 73.7 bits (173), Expect = 7e-13
Identities = 49/205 (23%), Positives = 106/205 (51%), Gaps = 7/205 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + L +
Sbjct: 88 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEI 147
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L++A EE +++ EVA RK+ IE DLE++EER+ A+ K E ++
Sbjct: 148 QLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESKCSELEEELKN 200
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
K LE +A++ ++ D+ ++K ++A+ +++ R +A +E ++ ED
Sbjct: 201 VTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDE 260
Query: 183 VKSGDAKISELEEELKVVGNSLKSL 207
+ + K + EEL N + S+
Sbjct: 261 LYAQKLKYKAISEELDHALNDMTSI 285
Score = 31.1 bits (67), Expect = 4.6
Identities = 15/94 (15%), Positives = 45/94 (47%)
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
M + ++ + Q + + ++ ++A + A+ +S ++ +LA ++ +L+ ED +
Sbjct: 1 MMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDK 60
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ + +E+L++ E N+R++
Sbjct: 61 YSEALKDAQEKLELAEKKAADAEAEVASLNRRIQ 94
Score = 31.1 bits (67), Expect = 4.6
Identities = 14/80 (17%), Positives = 40/80 (50%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +++ + + ++D ++ + ++A RAE V +L+K + +E++L
Sbjct: 205 LKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQ 264
Query: 61 KNKLEQANKDLEEKEKQLTA 80
K K + +++L+ +T+
Sbjct: 265 KLKYKAISEELDHALNDMTS 284
>BC008407-1|AAH08407.1| 285|Homo sapiens tropomyosin 3 protein.
Length = 285
Score = 238 bits (582), Expect = 2e-62
Identities = 120/281 (42%), Positives = 187/281 (66%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M+AIKKKMQ +KL+K+NA+D+A+ E + + A R++++ +E+ +QKKL E++L
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
L+ A + LE EK+ EAEVA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E
Sbjct: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+R + ++K SELEEELK V N+LKSLE EK +Q+ +++
Sbjct: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LEDEL K +YK++++E+D ++
Sbjct: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDM 282
Score = 73.7 bits (173), Expect = 7e-13
Identities = 49/205 (23%), Positives = 106/205 (51%), Gaps = 7/205 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + L +
Sbjct: 88 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEI 147
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L++A EE +++ EVA RK+ IE DLE++EER+ A+ K E ++
Sbjct: 148 QLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESKCSELEEELKN 200
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
K LE +A++ ++ D+ ++K ++A+ +++ R +A +E ++ ED
Sbjct: 201 VTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDE 260
Query: 183 VKSGDAKISELEEELKVVGNSLKSL 207
+ + K + EEL N + S+
Sbjct: 261 LYAQKLKYKAISEELDHALNDMTSI 285
Score = 31.1 bits (67), Expect = 4.6
Identities = 15/94 (15%), Positives = 45/94 (47%)
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
M + ++ + Q + + ++ ++A + A+ +S ++ +LA ++ +L+ ED +
Sbjct: 1 MMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDK 60
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ + +E+L++ E N+R++
Sbjct: 61 YSEALKDAQEKLELAEKKAADAEAEVASLNRRIQ 94
Score = 31.1 bits (67), Expect = 4.6
Identities = 14/80 (17%), Positives = 40/80 (50%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +++ + + ++D ++ + ++A RAE V +L+K + +E++L
Sbjct: 205 LKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQ 264
Query: 61 KNKLEQANKDLEEKEKQLTA 80
K K + +++L+ +T+
Sbjct: 265 KLKYKAISEELDHALNDMTS 284
>AL590431-11|CAH71269.1| 284|Homo sapiens tropomyosin 3 protein.
Length = 284
Score = 238 bits (582), Expect = 2e-62
Identities = 120/281 (42%), Positives = 187/281 (66%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M+AIKKKMQ +KL+K+NA+D+A+ E + + A R++++ +E+ +QKKL E++L
Sbjct: 1 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 60
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
L+ A + LE EK+ EAEVA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E
Sbjct: 121 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 180
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+R + ++K SELEEELK V N+LKSLE EK +Q+ +++
Sbjct: 181 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 240
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LEDEL K +YK++++E+D ++
Sbjct: 241 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDM 281
Score = 73.7 bits (173), Expect = 7e-13
Identities = 49/205 (23%), Positives = 106/205 (51%), Gaps = 7/205 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + L +
Sbjct: 87 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEI 146
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L++A EE +++ EVA RK+ IE DLE++EER+ A+ K E ++
Sbjct: 147 QLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESKCSELEEELKN 199
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
K LE +A++ ++ D+ ++K ++A+ +++ R +A +E ++ ED
Sbjct: 200 VTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDE 259
Query: 183 VKSGDAKISELEEELKVVGNSLKSL 207
+ + K + EEL N + S+
Sbjct: 260 LYAQKLKYKAISEELDHALNDMTSI 284
Score = 31.1 bits (67), Expect = 4.6
Identities = 14/80 (17%), Positives = 40/80 (50%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +++ + + ++D ++ + ++A RAE V +L+K + +E++L
Sbjct: 204 LKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQ 263
Query: 61 KNKLEQANKDLEEKEKQLTA 80
K K + +++L+ +T+
Sbjct: 264 KLKYKAISEELDHALNDMTS 283
>BC007433-1|AAH07433.1| 284|Homo sapiens tropomyosin 1 (alpha)
protein.
Length = 284
Score = 233 bits (571), Expect = 4e-61
Identities = 115/281 (40%), Positives = 188/281 (66%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
MDAIKKKMQ +KL+K+NA+D+A+ E + A R++++ +E+ LQKKL E++L
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
DE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+R + + ++ +LEE+L+++ +LK+L +E+K +Q+ + +
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LEDEL K +YK++++E+D ++
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDM 281
Score = 31.5 bits (68), Expect = 3.5
Identities = 14/67 (20%), Positives = 34/67 (50%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 73
++D ++ + ++A RAE V +L+K + +E++L K K + +++L+
Sbjct: 217 KEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDH 276
Query: 74 KEKQLTA 80
+T+
Sbjct: 277 ALNDMTS 283
>AL133410-1|CAI10975.1| 284|Homo sapiens tropomyosin 2 (beta)
protein.
Length = 284
Score = 230 bits (562), Expect = 5e-60
Identities = 116/281 (41%), Positives = 182/281 (64%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+R + ++K +LEEELK+V N+LKSLE +K + + +++
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LE+ L K+ + +D T EL
Sbjct: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLEL 281
>AK023385-1|BAB14554.1| 284|Homo sapiens protein ( Homo sapiens
cDNA FLJ13323 fis, clone OVARC1001731, highly similar to
TROPOMYOSIN ALPHA CHAIN, FIBROBLAST ISOFORM F2. ).
Length = 284
Score = 229 bits (559), Expect = 1e-59
Identities = 120/281 (42%), Positives = 180/281 (64%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M+AIKKKMQ +KL+K+NA+D+A+ E + A + ++V EE+ LQKKL E++L
Sbjct: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
L+ A + LE EK+ + E +VAALNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E ELE AE
Sbjct: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+R + + K +LEEELK V N+LKSLE + EK +++ +++
Sbjct: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+TV KL+K +D LE++L K+ L +D T EL
Sbjct: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNEL 281
Score = 60.5 bits (140), Expect = 7e-09
Identities = 42/205 (20%), Positives = 103/205 (50%), Gaps = 7/205 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A+ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + + +
Sbjct: 87 ALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEM 146
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L++A EE +++ EVA RK+ +E +LE++EER+ ++ K + ++
Sbjct: 147 QLKEAKHIAEEADRKYE----EVA---RKLVILEGELERAEERAEVSELKCGDLEEELKN 199
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
K LE +++ E+ D+ ++K ++A+ +++ R +A +E ++ E++
Sbjct: 200 VTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEK 259
Query: 183 VKSGDAKISELEEELKVVGNSLKSL 207
+ + L + L N L +
Sbjct: 260 LAQAKEENVGLHQTLDQTLNELNCI 284
>AY640414-1|AAT68294.1| 284|Homo sapiens sarcomeric tropomyosin
kappa protein.
Length = 284
Score = 226 bits (553), Expect = 6e-59
Identities = 116/281 (41%), Positives = 180/281 (64%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
MDAIKKKMQ +KL+K+NA+D+A+ E + A R++++ E++ +K L E++
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+L +A L E+ EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
DE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+R + + K +ELEEELK V N LKSLE EK +Q+ + +
Sbjct: 181 ERAELSEGKCAELEEELKTVTNDLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LEDEL K +YK++++E+D ++
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDM 281
Score = 69.3 bits (162), Expect = 1e-11
Identities = 45/205 (21%), Positives = 105/205 (51%), Gaps = 7/205 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + + +
Sbjct: 87 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEI 146
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 147 QLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEEELKT 199
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++ ED
Sbjct: 200 VTNDLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDE 259
Query: 183 VKSGDAKISELEEELKVVGNSLKSL 207
+ + K + EEL N + S+
Sbjct: 260 LYAQKLKYKAISEELDHALNDMTSI 284
Score = 32.3 bits (70), Expect = 2.0
Identities = 14/80 (17%), Positives = 40/80 (50%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +++ + + ++D ++ + ++A RAE V +L+K + +E++L
Sbjct: 204 LKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQ 263
Query: 61 KNKLEQANKDLEEKEKQLTA 80
K K + +++L+ +T+
Sbjct: 264 KLKYKAISEELDHALNDMTS 283
>M19267-1|AAA36771.1| 284|Homo sapiens protein ( Human tropomyosin
mRNA, complete cds. ).
Length = 284
Score = 225 bits (550), Expect = 1e-58
Identities = 113/281 (40%), Positives = 184/281 (65%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
MDAIKKKMQ +KL+K+NA+D+A+ E + A R++++ +E+ LQKKL E++L
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
DE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+R + + ++ +LEE+L+++ +LK+L +E+K +Q+ + +
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LE+++ K+ S+ +D T EL
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
>M75165-1|AAB59509.1| 284|Homo sapiens tropomyosin protein.
Length = 284
Score = 223 bits (546), Expect = 4e-58
Identities = 113/281 (40%), Positives = 181/281 (64%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+R + +++ +LEEEL+ + +LKSL SEE+ + + +++
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LE+ L K+ + +D T EL
Sbjct: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLEL 281
>M74817-1|AAA61230.1| 284|Homo sapiens tropomyosin-1 protein.
Length = 284
Score = 223 bits (546), Expect = 4e-58
Identities = 113/281 (40%), Positives = 181/281 (64%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+R + +++ +LEEEL+ + +LKSL SEE+ + + +++
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LE+ L K+ + +D T EL
Sbjct: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLEL 281
>M12125-1|AAA36773.1| 284|Homo sapiens protein ( Human fibroblast
muscle-type tropomyosin mRNA, complete cds. ).
Length = 284
Score = 223 bits (546), Expect = 4e-58
Identities = 113/281 (40%), Positives = 181/281 (64%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+R + +++ +LEEEL+ + +LKSL SEE+ + + +++
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LE+ L K+ + +D T EL
Sbjct: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLEL 281
>BC011776-1|AAH11776.1| 284|Homo sapiens tropomyosin 2 (beta)
protein.
Length = 284
Score = 223 bits (546), Expect = 4e-58
Identities = 113/281 (40%), Positives = 181/281 (64%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+R + +++ +LEEEL+ + +LKSL SEE+ + + +++
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LE+ L K+ + +D T EL
Sbjct: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLEL 281
>AL133410-2|CAI10974.1| 284|Homo sapiens tropomyosin 2 (beta)
protein.
Length = 284
Score = 223 bits (546), Expect = 4e-58
Identities = 113/281 (40%), Positives = 181/281 (64%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+R + +++ +LEEEL+ + +LKSL SEE+ + + +++
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LE+ L K+ + +D T EL
Sbjct: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLEL 281
>AL133410-3|CAI10976.1| 322|Homo sapiens tropomyosin 2 (beta)
protein.
Length = 322
Score = 222 bits (543), Expect = 1e-57
Identities = 111/262 (42%), Positives = 174/262 (66%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+R + ++K +LEEELK+V N+LKSLE +K + + +++
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 XXXKTVKKLQKEVDRLEDELGI 262
++V KL+K +D LE+ I
Sbjct: 241 FAERSVAKLEKTIDDLEESTSI 262
Score = 46.0 bits (104), Expect = 2e-04
Identities = 36/184 (19%), Positives = 85/184 (46%), Gaps = 14/184 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + L +
Sbjct: 87 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEM 146
Query: 63 KLEQA-------NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+L++A ++ EE ++L E E +++ EE E +E + G +++L
Sbjct: 147 QLKEAKHIAEDSDRKYEEVARKLVILEGE-------LERSEERAEVAESKCGDLEEELKI 199
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
+ + + EE + L +LKEA AE A+ ++ + + +E+
Sbjct: 200 VTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEES 259
Query: 176 LEVA 179
+A
Sbjct: 260 TSIA 263
Score = 45.6 bits (103), Expect = 2e-04
Identities = 35/148 (23%), Positives = 66/148 (44%), Gaps = 3/148 (2%)
Query: 3 AIKKKMQAMKLEKDNAM---DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
A + + MK+ ++ AM +K + E Q ++A AE + + E+ +KL +E +L
Sbjct: 119 AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 178
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
++ + E A + E++L + +L + + +K EE ++KL EA+
Sbjct: 179 SEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETR 238
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQ 147
A+ R LE EE T +
Sbjct: 239 AEFAERSVAKLEKTIDDLEESTSIATTE 266
>AK223258-1|BAD96978.1| 284|Homo sapiens tropomyosin 2 (beta)
isoform 2 variant protein.
Length = 284
Score = 221 bits (541), Expect = 2e-57
Identities = 112/281 (39%), Positives = 181/281 (64%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+++A + LE+ EK+ T EA+VA+L+R++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLSRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+R + +++ +LEEEL+ + +LKSL SEE+ + + +++
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LE+ L K+ + +D T EL
Sbjct: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLEL 281
>AF209746-1|AAF17621.1| 257|Homo sapiens beta tropomyosin protein.
Length = 257
Score = 214 bits (522), Expect = 3e-55
Identities = 107/257 (41%), Positives = 171/257 (66%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+R + +++ +LEEEL+ + +LKSL SEE+ + + +++
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 241 XXXKTVKKLQKEVDRLE 257
++V KL+K +D LE
Sbjct: 241 FAERSVAKLEKTIDDLE 257
>M19714-1|AAA61226.1| 264|Homo sapiens TPM1 protein.
Length = 264
Score = 210 bits (512), Expect = 6e-54
Identities = 108/261 (41%), Positives = 168/261 (64%)
Query: 21 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 80
+A+ E + A R++++ +E+ LQKKL E++L L+ A + LE EK+ T
Sbjct: 1 RAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATD 60
Query: 81 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 140
EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++ADE+ R KV+E+RAQ+DEE+
Sbjct: 61 AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK 120
Query: 141 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 200
M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE+R + + K +ELEEELK V
Sbjct: 121 MEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTV 180
Query: 201 GNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
N+LKSLE EK +Q+ + + ++V KL+K +D LEDEL
Sbjct: 181 TNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDEL 240
Query: 261 GINKDRYKSLADEMDSTFAEL 281
K +YK++++E+D ++
Sbjct: 241 YAQKLKYKAISEELDHALNDM 261
Score = 72.9 bits (171), Expect = 1e-12
Identities = 51/223 (22%), Positives = 105/223 (47%), Gaps = 16/223 (7%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D + K +A+K +A +K + E++A DA +N ++ ++++L + +E L
Sbjct: 35 DELDKYSEALK----DAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATAL 90
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEED---LEKSEERSGTAQQKLL 114
KLE+A K +E E+ + E+ K++ Q++E E ++ + +KL+
Sbjct: 91 QKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLV 150
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
+ + ++ E + + EE + +TN LK AE K D ++ + D
Sbjct: 151 IIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSD 210
Query: 175 ELEVAEDRVKSGDAKISELEEEL-----KVVGNSLKSLEVSEE 212
+L+ AE R + + +++LE+ + ++ LK +SEE
Sbjct: 211 KLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEE 253
Score = 70.9 bits (166), Expect = 5e-12
Identities = 54/216 (25%), Positives = 101/216 (46%), Gaps = 14/216 (6%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
+++KK++ + E D + +++ A +A +V L +++ VEE+L +
Sbjct: 25 SLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQE 84
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L A + LEE EK +E + + + Q+ EE +E E + A+ +A + +E
Sbjct: 85 RLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEE 144
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
R ++E+ ++ EER AE ++GK E+ +L V + L+ E +
Sbjct: 145 VARKLVIIESDLERAEER--------------AELSEGKCAELEEELKTVTNNLKSLEAQ 190
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
+ K EEE+KV+ + LK E E A + V
Sbjct: 191 AEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSV 226
Score = 69.7 bits (163), Expect = 1e-11
Identities = 45/205 (21%), Positives = 105/205 (51%), Gaps = 7/205 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + + +
Sbjct: 67 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEI 126
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 127 QLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEEELKT 179
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++ ED
Sbjct: 180 VTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDE 239
Query: 183 VKSGDAKISELEEELKVVGNSLKSL 207
+ + K + EEL N + S+
Sbjct: 240 LYAQKLKYKAISEELDHALNDMTSM 264
Score = 43.2 bits (97), Expect = 0.001
Identities = 47/188 (25%), Positives = 85/188 (45%), Gaps = 20/188 (10%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNE--EVRELQKKLAQ-VEEDL 57
+D ++++ + + A AD E+ + RA+K E E++E+Q K A+ + ED
Sbjct: 79 LDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 138
Query: 58 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
K E+ + L E L E K ++EE+L ++ T K LEAQ
Sbjct: 139 ---DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEEL-----KTVTNNLKSLEAQ 190
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
+ + + EE + L+++LKEA AE A+ ++ + + +EDEL
Sbjct: 191 ---------AEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELY 241
Query: 178 VAEDRVKS 185
+ + K+
Sbjct: 242 AQKLKYKA 249
Score = 32.3 bits (70), Expect = 2.0
Identities = 14/80 (17%), Positives = 40/80 (50%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +++ + + ++D ++ + ++A RAE V +L+K + +E++L
Sbjct: 184 LKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQ 243
Query: 61 KNKLEQANKDLEEKEKQLTA 80
K K + +++L+ +T+
Sbjct: 244 KLKYKAISEELDHALNDMTS 263
>AK131384-1|BAD18535.1| 326|Homo sapiens protein ( Homo sapiens
cDNA FLJ16459 fis, clone BRCAN2002473, moderately
similar to Tropomyosin, fibroblast isoform 2. ).
Length = 326
Score = 205 bits (500), Expect = 2e-52
Identities = 110/279 (39%), Positives = 170/279 (60%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A +K ++ + E+D +++ E A A K+ +E+ LQKKL E++L
Sbjct: 45 AKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKLEDELVSLQKKLKGTEDELDKYSE 104
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++ADE
Sbjct: 105 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 164
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE+R
Sbjct: 165 SERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEER 224
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXX 242
+ + K +ELEEELK V N+LKSLE EK +Q+ + +
Sbjct: 225 AELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFA 284
Query: 243 XKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LE+++ K+ S+ +D T EL
Sbjct: 285 ERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 323
Score = 110 bits (264), Expect = 6e-24
Identities = 76/287 (26%), Positives = 136/287 (47%), Gaps = 9/287 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
MDAIKKKMQ +KL+K+NA+D+A+ E + A R++++ E++ +K L E++
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+L +A L E+ E E+ +L +K++ E++L+K E AQ+KL A++ A
Sbjct: 61 LEELHKAEDSLLAAEEAAAKLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKA 120
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------E 173
+ L R Q EE +D+ +L A E+A+ +DE R + + E
Sbjct: 121 TDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDE 180
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXX 233
+++E+ E ++K + + + + V L +E E+A +R E
Sbjct: 181 EKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELK 240
Query: 234 XXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
+K ++ DR E+E+ + D+ K E + FAE
Sbjct: 241 TVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEA--ETRAEFAE 285
Score = 71.7 bits (168), Expect = 3e-12
Identities = 46/203 (22%), Positives = 97/203 (47%), Gaps = 11/203 (5%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D + K +A+K +A +K + E++A DA +N ++ ++++L + +E L
Sbjct: 97 DELDKYSEALK----DAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATAL 152
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEED---LEKSEERSGTAQQKLL 114
KLE+A K +E E+ + E+ K++ Q++E E ++ + +KL+
Sbjct: 153 QKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLV 212
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
+ + ++ E + + EE + +TN LK AE K D ++ + D
Sbjct: 213 IIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSD 272
Query: 175 ELEVAEDRVKSGDAKISELEEEL 197
+L+ AE R + + +++LE+ +
Sbjct: 273 KLKEAETRAEFAERSVTKLEKSI 295
Score = 47.2 bits (107), Expect = 7e-05
Identities = 31/140 (22%), Positives = 62/140 (44%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D ++ M+ ++ +K + E Q ++A AE + + E+ +KL +E DL +
Sbjct: 163 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 222
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
+ E + E E++L + +L + ++ + ++ EE KL EA+ A+
Sbjct: 223 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 282
Query: 122 ENNRMCKVLENRAQQDEERM 141
R LE EE++
Sbjct: 283 FAERSVTKLEKSIDDLEEKV 302
Score = 39.5 bits (88), Expect = 0.013
Identities = 44/184 (23%), Positives = 84/184 (45%), Gaps = 20/184 (10%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNE--EVRELQKKLAQ-VEEDL 57
+D ++++ + + A AD E+ + RA+K E E++E+Q K A+ + ED
Sbjct: 141 LDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 200
Query: 58 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
K E+ + L E L E K ++EE+L ++ T K LEAQ
Sbjct: 201 ---DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEEL-----KTVTNNLKSLEAQ 252
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
+ + + EE + L+++LKEA AE A+ ++ + + +E+++
Sbjct: 253 ---------AEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVA 303
Query: 178 VAED 181
A++
Sbjct: 304 HAKE 307
>AL590431-12|CAH71270.1| 242|Homo sapiens tropomyosin 3 protein.
Length = 242
Score = 177 bits (430), Expect = 5e-44
Identities = 94/241 (39%), Positives = 151/241 (62%), Gaps = 3/241 (1%)
Query: 41 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 100
E +++ + L +E+ + + E K EE+ KQL E E+AA+ +K++ E++L+
Sbjct: 2 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQL---EDELAAMQKKLKGTEDELD 58
Query: 101 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+++ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD
Sbjct: 59 RAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR 118
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
K +EV+RKL +E +LE E+R + ++K SELEEELK V N+LKSLE EK +Q+ ++
Sbjct: 119 KYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDK 178
Query: 221 FXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
+ ++V KL+K +D LEDEL K +YK++++E+D +
Sbjct: 179 YEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALND 238
Query: 281 L 281
+
Sbjct: 239 M 239
Score = 102 bits (244), Expect = 2e-21
Identities = 67/231 (29%), Positives = 119/231 (51%), Gaps = 19/231 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M+AIKKKMQ +KL+K+NA+D+A+ E + + A R++++ +E+ +QKKL E++L
Sbjct: 1 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDRA 60
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 61 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 120
Query: 121 DENNRMCKVLENRAQQDEER--------------MDQLTNQLKEARLLAEDADGKSDEVS 166
+E R ++E ++ EER + +TN LK AE K D+
Sbjct: 121 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 180
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEE-----ELKVVGNSLKSLEVSEE 212
++ + D+L+ AE R + + +++LE+ E ++ LK +SEE
Sbjct: 181 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEE 231
Score = 31.1 bits (67), Expect = 4.6
Identities = 14/80 (17%), Positives = 40/80 (50%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +++ + + ++D ++ + ++A RAE V +L+K + +E++L
Sbjct: 162 LKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQ 221
Query: 61 KNKLEQANKDLEEKEKQLTA 80
K K + +++L+ +T+
Sbjct: 222 KLKYKAISEELDHALNDMTS 241
>AK092690-1|BAC03946.1| 243|Homo sapiens protein ( Homo sapiens
cDNA FLJ35371 fis, clone SKMUS2001740, highly similar to
TROPOMYOSIN ALPHA CHAIN, SKELETAL MUSCLE TYPE. ).
Length = 243
Score = 177 bits (430), Expect = 5e-44
Identities = 94/241 (39%), Positives = 151/241 (62%), Gaps = 3/241 (1%)
Query: 41 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 100
E +++ + L +E+ + + E K EE+ KQL E E+AA+ +K++ E++L+
Sbjct: 3 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQL---EDELAAMQKKLKGTEDELD 59
Query: 101 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+++ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD
Sbjct: 60 RAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR 119
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
K +EV+RKL +E +LE E+R + ++K SELEEELK V N+LKSLE EK +Q+ ++
Sbjct: 120 KYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDK 179
Query: 221 FXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
+ ++V KL+K +D LEDEL K +YK++++E+D +
Sbjct: 180 YEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALND 239
Query: 281 L 281
+
Sbjct: 240 M 240
Score = 102 bits (244), Expect = 2e-21
Identities = 67/231 (29%), Positives = 119/231 (51%), Gaps = 19/231 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M+AIKKKMQ +KL+K+NA+D+A+ E + + A R++++ +E+ +QKKL E++L
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDRA 61
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 62 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 121
Query: 121 DENNRMCKVLENRAQQDEER--------------MDQLTNQLKEARLLAEDADGKSDEVS 166
+E R ++E ++ EER + +TN LK AE K D+
Sbjct: 122 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 181
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEE-----ELKVVGNSLKSLEVSEE 212
++ + D+L+ AE R + + +++LE+ E ++ LK +SEE
Sbjct: 182 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEE 232
Score = 31.1 bits (67), Expect = 4.6
Identities = 14/80 (17%), Positives = 40/80 (50%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +++ + + ++D ++ + ++A RAE V +L+K + +E++L
Sbjct: 163 LKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQ 222
Query: 61 KNKLEQANKDLEEKEKQLTA 80
K K + +++L+ +T+
Sbjct: 223 KLKYKAISEELDHALNDMTS 242
>BC053545-1|AAH53545.1| 245|Homo sapiens tropomyosin 1 (alpha)
protein.
Length = 245
Score = 176 bits (429), Expect = 6e-44
Identities = 89/235 (37%), Positives = 147/235 (62%)
Query: 40 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 99
+ + +++K+ ++E + + ++L+ + K EA+VA+LNR++Q +EE+L
Sbjct: 4 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEEL 63
Query: 100 EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 159
++++ER TA QKL EA+++ADE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD
Sbjct: 64 DRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 123
Query: 160 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
K +EV+RKL +E +LE AE+R + + K +ELEEELK V N+LKSLE EK +Q+ +
Sbjct: 124 RKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKED 183
Query: 220 EFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
+ ++V KL+K +D LED+L ++ + L +E+
Sbjct: 184 RYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNEL 238
Score = 65.7 bits (153), Expect = 2e-10
Identities = 44/200 (22%), Positives = 103/200 (51%), Gaps = 7/200 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + + +
Sbjct: 51 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEI 110
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 111 QLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEEELKT 163
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++ ED+
Sbjct: 164 VTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQ 223
Query: 183 VKSGDAKISELEEELKVVGN 202
+ + L ELK+ N
Sbjct: 224 LYQQLEQNRRLTNELKLALN 243
Score = 63.7 bits (148), Expect = 7e-10
Identities = 47/208 (22%), Positives = 91/208 (43%), Gaps = 9/208 (4%)
Query: 80 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 139
A + + A+ RK++ ++E + +EER+GT Q++L ++ + L R Q EE
Sbjct: 2 AGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEE 61
Query: 140 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELEVAEDRVKSGDAKISE 192
+D+ +L A E+A+ +DE R + + E+++E+ E ++K +
Sbjct: 62 ELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAED 121
Query: 193 LEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKE 252
+ + + V L +E E+A +R E +K ++
Sbjct: 122 ADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQK 181
Query: 253 VDRLEDELGINKDRYKSLADEMDSTFAE 280
DR E+E+ + D+ K E + FAE
Sbjct: 182 EDRYEEEIKVLSDKLKEA--ETRAEFAE 207
Score = 51.2 bits (117), Expect = 4e-06
Identities = 35/164 (21%), Positives = 73/164 (44%), Gaps = 6/164 (3%)
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
+ S + R + L+ +A EER L +L R L E A+ ++R++ VE
Sbjct: 1 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 60
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXX 233
+EL+ A++R+ + + +LEE K S + ++V E +A + E+
Sbjct: 61 EELDRAQERLATA---LQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKH 117
Query: 234 XXXXXXXXXXKTVKKL---QKEVDRLEDELGINKDRYKSLADEM 274
+ +KL + +++R E+ +++ + L +E+
Sbjct: 118 IAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEEL 161
Score = 42.7 bits (96), Expect = 0.001
Identities = 48/200 (24%), Positives = 93/200 (46%), Gaps = 22/200 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNE--EVRELQKKLAQ-VEEDL 57
+D ++++ + + A AD E+ + RA+K E E++E+Q K A+ + ED
Sbjct: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 122
Query: 58 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
K E+ + L E L E K ++EE+L ++ T K LEAQ
Sbjct: 123 ---DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEEL-----KTVTNNLKSLEAQ 174
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL- 176
+ + + EE + L+++LKEA AE A+ ++ + + +ED+L
Sbjct: 175 ---------AEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLY 225
Query: 177 -EVAEDRVKSGDAKISELEE 195
++ ++R + + K++ E+
Sbjct: 226 QQLEQNRRLTNELKLALNED 245
>BC050473-1|AAH50473.1| 287|Homo sapiens TPM1 protein protein.
Length = 287
Score = 176 bits (429), Expect = 6e-44
Identities = 89/235 (37%), Positives = 147/235 (62%)
Query: 40 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 99
+ + +++K+ ++E + + ++L+ + K EA+VA+LNR++Q +EE+L
Sbjct: 46 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEEL 105
Query: 100 EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 159
++++ER TA QKL EA+++ADE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD
Sbjct: 106 DRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 165
Query: 160 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
K +EV+RKL +E +LE AE+R + + K +ELEEELK V N+LKSLE EK +Q+ +
Sbjct: 166 RKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKED 225
Query: 220 EFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
+ ++V KL+K +D LED+L ++ + L +E+
Sbjct: 226 RYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNEL 280
Score = 65.7 bits (153), Expect = 2e-10
Identities = 44/200 (22%), Positives = 103/200 (51%), Gaps = 7/200 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + + +
Sbjct: 93 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEI 152
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 153 QLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEEELKT 205
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++ ED+
Sbjct: 206 VTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQ 265
Query: 183 VKSGDAKISELEEELKVVGN 202
+ + L ELK+ N
Sbjct: 266 LYQQLEQNRRLTNELKLALN 285
Score = 63.7 bits (148), Expect = 7e-10
Identities = 47/208 (22%), Positives = 91/208 (43%), Gaps = 9/208 (4%)
Query: 80 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 139
A + + A+ RK++ ++E + +EER+GT Q++L ++ + L R Q EE
Sbjct: 44 AGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEE 103
Query: 140 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELEVAEDRVKSGDAKISE 192
+D+ +L A E+A+ +DE R + + E+++E+ E ++K +
Sbjct: 104 ELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAED 163
Query: 193 LEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKE 252
+ + + V L +E E+A +R E +K ++
Sbjct: 164 ADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQK 223
Query: 253 VDRLEDELGINKDRYKSLADEMDSTFAE 280
DR E+E+ + D+ K E + FAE
Sbjct: 224 EDRYEEEIKVLSDKLKEA--ETRAEFAE 249
Score = 51.2 bits (117), Expect = 4e-06
Identities = 35/164 (21%), Positives = 73/164 (44%), Gaps = 6/164 (3%)
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
+ S + R + L+ +A EER L +L R L E A+ ++R++ VE
Sbjct: 43 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 102
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXX 233
+EL+ A++R+ + + +LEE K S + ++V E +A + E+
Sbjct: 103 EELDRAQERLATA---LQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKH 159
Query: 234 XXXXXXXXXXKTVKKL---QKEVDRLEDELGINKDRYKSLADEM 274
+ +KL + +++R E+ +++ + L +E+
Sbjct: 160 IAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEEL 203
Score = 42.7 bits (96), Expect = 0.001
Identities = 48/200 (24%), Positives = 93/200 (46%), Gaps = 22/200 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNE--EVRELQKKLAQ-VEEDL 57
+D ++++ + + A AD E+ + RA+K E E++E+Q K A+ + ED
Sbjct: 105 LDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 164
Query: 58 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
K E+ + L E L E K ++EE+L ++ T K LEAQ
Sbjct: 165 ---DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEEL-----KTVTNNLKSLEAQ 216
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL- 176
+ + + EE + L+++LKEA AE A+ ++ + + +ED+L
Sbjct: 217 ---------AEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLY 267
Query: 177 -EVAEDRVKSGDAKISELEE 195
++ ++R + + K++ E+
Sbjct: 268 QQLEQNRRLTNELKLALNED 287
>AL590431-9|CAH71267.1| 248|Homo sapiens tropomyosin 3 protein.
Length = 248
Score = 176 bits (428), Expect = 8e-44
Identities = 90/239 (37%), Positives = 149/239 (62%)
Query: 43 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 102
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 103 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 163 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFX 222
+EV+RKL +E +LE E+R + ++K SELEEELK V N+LKSLE EK +Q+ +++
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 186
Query: 223 XXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LED+L K+ + +D T +L
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDL 245
Score = 83.0 bits (196), Expect = 1e-15
Identities = 56/232 (24%), Positives = 112/232 (48%), Gaps = 15/232 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 121 DENNRMCKVLENRAQQDEER--------------MDQLTNQLKEARLLAEDADGKSDEVS 166
+E R ++E ++ EER + +TN LK AE K D+
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 186
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
++ + D+L+ AE R + + +++LE+ + + + LK + E QR+
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTK-EEHLCTQRM 237
>AL590431-10|CAH71268.1| 247|Homo sapiens tropomyosin 3 protein.
Length = 247
Score = 175 bits (425), Expect = 2e-43
Identities = 90/239 (37%), Positives = 151/239 (63%)
Query: 43 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 102
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 103 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 163 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFX 222
+EV+RKL +E +LE E+R + ++K SELEEELK V N+LKSLE EK +Q+ +++
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 186
Query: 223 XXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LE+ L +R + L++E+ T +L
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
Score = 81.4 bits (192), Expect = 3e-15
Identities = 56/218 (25%), Positives = 106/218 (48%), Gaps = 14/218 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+E R ++E ++ EER AE A+ K E+ +L V + L+ E
Sbjct: 127 EEVARKLVIIEGDLERTEER--------------AELAESKCSELEEELKNVTNNLKSLE 172
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
+ + K + EEE+K++ + LK E E A + V
Sbjct: 173 AQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSV 210
Score = 70.5 bits (165), Expect = 6e-12
Identities = 49/202 (24%), Positives = 106/202 (52%), Gaps = 7/202 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + L +
Sbjct: 51 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEI 110
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L++A EE +++ EVA RK+ IE DLE++EER+ A+ K E ++
Sbjct: 111 QLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESKCSELEEELKN 163
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
K LE +A++ ++ D+ ++K ++A+ +++ R +A +E ++ E+R
Sbjct: 164 VTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEER 223
Query: 183 VKSGDAKISELEEELKVVGNSL 204
+ S + L ELK+ + L
Sbjct: 224 LYSQLERNRLLSNELKLTLHDL 245
Score = 32.3 bits (70), Expect = 2.0
Identities = 18/112 (16%), Positives = 49/112 (43%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+ + +K+ ++ + + ++A+ E + + + V ++ L+ + + + +
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 186
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
+++ L+E E + E VA L + + +EE L ER+ +L
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNEL 238
>AB209041-1|BAD92278.1| 303|Homo sapiens TPM1 protein variant
protein.
Length = 303
Score = 173 bits (422), Expect = 4e-43
Identities = 88/235 (37%), Positives = 146/235 (62%)
Query: 40 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 99
+ + +++K+ ++E + + ++L+ + K EA+VA+LNR++Q +EE+L
Sbjct: 62 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEEL 121
Query: 100 EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 159
++++ER TA QKL EA+++AD + R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD
Sbjct: 122 DRAQERLATALQKLEEAEKAADGSERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 181
Query: 160 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
K +EV+RKL +E +LE AE+R + + K +ELEEELK V N+LKSLE EK +Q+ +
Sbjct: 182 RKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKED 241
Query: 220 EFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
+ ++V KL+K +D LED+L ++ + L +E+
Sbjct: 242 RYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNEL 296
Score = 76.6 bits (180), Expect = 9e-14
Identities = 53/231 (22%), Positives = 112/231 (48%), Gaps = 15/231 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+++K+++++ + D A ++A T +++ E +V L +++ VEE+L
Sbjct: 65 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 124
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + Q+ EE +E E + A+ +A +
Sbjct: 125 QERLATALQKLEEAEKAADGSERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 184
Query: 121 DENNRMCKVLENRAQQDEERMD--------------QLTNQLKEARLLAEDADGKSDEVS 166
+E R ++E+ ++ EER + +TN LK AE K D
Sbjct: 185 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 244
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL-KSLEVSEEKANQ 216
++ + D+L+ AE R + + +++LE+ + + + L + LE + N+
Sbjct: 245 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNE 295
Score = 64.5 bits (150), Expect = 4e-10
Identities = 44/200 (22%), Positives = 102/200 (51%), Gaps = 7/200 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A+ ++ ++ + + EE + + +
Sbjct: 109 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADGSERGMKVIESRAQKDEEKMEIQEI 168
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 169 QLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEEELKT 221
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++ ED+
Sbjct: 222 VTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQ 281
Query: 183 VKSGDAKISELEEELKVVGN 202
+ + L ELK+ N
Sbjct: 282 LYQQLEQNRRLTNELKLALN 301
Score = 61.7 bits (143), Expect = 3e-09
Identities = 46/208 (22%), Positives = 92/208 (44%), Gaps = 9/208 (4%)
Query: 80 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL-----LEAQQSAD--ENNRMCKVLEN 132
A + + A+ RK++ ++E + +EER+GT Q++L L AD NR +++E
Sbjct: 60 AGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEE 119
Query: 133 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 192
+ +ER+ +L+EA A+ ++ + + E+++E+ E ++K +
Sbjct: 120 ELDRAQERLATALQKLEEAEKAADGSERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAED 179
Query: 193 LEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKE 252
+ + + V L +E E+A +R E +K ++
Sbjct: 180 ADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQK 239
Query: 253 VDRLEDELGINKDRYKSLADEMDSTFAE 280
DR E+E+ + D+ K E + FAE
Sbjct: 240 EDRYEEEIKVLSDKLKEA--ETRAEFAE 265
Score = 51.2 bits (117), Expect = 4e-06
Identities = 35/164 (21%), Positives = 73/164 (44%), Gaps = 6/164 (3%)
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
+ S + R + L+ +A EER L +L R L E A+ ++R++ VE
Sbjct: 59 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 118
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXX 233
+EL+ A++R+ + + +LEE K S + ++V E +A + E+
Sbjct: 119 EELDRAQERLATA---LQKLEEAEKAADGSERGMKVIESRAQKDEEKMEIQEIQLKEAKH 175
Query: 234 XXXXXXXXXXKTVKKL---QKEVDRLEDELGINKDRYKSLADEM 274
+ +KL + +++R E+ +++ + L +E+
Sbjct: 176 IAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEEL 219
Score = 42.3 bits (95), Expect = 0.002
Identities = 48/200 (24%), Positives = 93/200 (46%), Gaps = 22/200 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNE--EVRELQKKLAQ-VEEDL 57
+D ++++ + + A AD E+ + RA+K E E++E+Q K A+ + ED
Sbjct: 121 LDRAQERLATALQKLEEAEKAADGSERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 180
Query: 58 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
K E+ + L E L E K ++EE+L ++ T K LEAQ
Sbjct: 181 ---DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEEL-----KTVTNNLKSLEAQ 232
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL- 176
+ + + EE + L+++LKEA AE A+ ++ + + +ED+L
Sbjct: 233 ---------AEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLY 283
Query: 177 -EVAEDRVKSGDAKISELEE 195
++ ++R + + K++ E+
Sbjct: 284 QQLEQNRRLTNELKLALNED 303
>X05276-1|CAA28888.1| 248|Homo sapiens protein ( Human mRNA for
fibroblast tropomyosin TM30 (pl). ).
Length = 248
Score = 173 bits (421), Expect = 6e-43
Identities = 89/236 (37%), Positives = 148/236 (62%)
Query: 46 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 105
+++K+ +++ +++ + ++L+ + ++ E +VAALNR++Q +EE+L++++ER
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 69
Query: 106 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 165
TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXX 225
+RKL +E ELE AE+R + + K +LEEELK V N+LKSLE + EK +++ +++
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEI 189
Query: 226 XXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+TV KL+K +D LE++L K+ L +D T EL
Sbjct: 190 KLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNEL 245
Score = 85.8 bits (203), Expect = 2e-16
Identities = 60/227 (26%), Positives = 112/227 (49%), Gaps = 10/227 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+K+K+QA++ + D A D+A +++ R EK +V L +++ VEE+L
Sbjct: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
Query: 121 DENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
+E R +LE ++ EER + L +LK + + S++ S K E
Sbjct: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+E+++ D++K + + +E E + V K+++ EEK Q EE
Sbjct: 187 EEIKLLSDKLKEAETR-AEFAE--RTVAKLEKTIDDLEEKLAQAKEE 230
Score = 60.5 bits (140), Expect = 7e-09
Identities = 42/205 (20%), Positives = 103/205 (50%), Gaps = 7/205 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A+ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + + +
Sbjct: 51 ALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEM 110
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L++A EE +++ EVA RK+ +E +LE++EER+ ++ K + ++
Sbjct: 111 QLKEAKHIAEEADRKYE----EVA---RKLVILEGELERAEERAEVSELKCGDLEEELKN 163
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
K LE +++ E+ D+ ++K ++A+ +++ R +A +E ++ E++
Sbjct: 164 VTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEK 223
Query: 183 VKSGDAKISELEEELKVVGNSLKSL 207
+ + L + L N L +
Sbjct: 224 LAQAKEENVGLHQTLDQTLNELNCI 248
Score = 48.0 bits (109), Expect = 4e-05
Identities = 35/159 (22%), Positives = 73/159 (45%), Gaps = 6/159 (3%)
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
S + R + L+ +A + E+R L +L R E A+G ++R++ VE+EL+
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXX 238
A++R+ + + +LEE K S + ++V E +A + E+
Sbjct: 66 AQERLATA---LQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEA 122
Query: 239 XXXXXKTVKK---LQKEVDRLEDELGINKDRYKSLADEM 274
+ +K L+ E++R E+ +++ + L +E+
Sbjct: 123 DRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEEL 161
>BT019634-1|AAV38440.1| 248|Homo sapiens tropomyosin 4 protein.
Length = 248
Score = 173 bits (421), Expect = 6e-43
Identities = 89/236 (37%), Positives = 148/236 (62%)
Query: 46 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 105
+++K+ +++ +++ + ++L+ + ++ E +VAALNR++Q +EE+L++++ER
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 69
Query: 106 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 165
TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXX 225
+RKL +E ELE AE+R + + K +LEEELK V N+LKSLE + EK +++ +++
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEI 189
Query: 226 XXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+TV KL+K +D LE++L K+ L +D T EL
Sbjct: 190 KLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNEL 245
Score = 85.8 bits (203), Expect = 2e-16
Identities = 60/227 (26%), Positives = 112/227 (49%), Gaps = 10/227 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+K+K+QA++ + D A D+A +++ R EK +V L +++ VEE+L
Sbjct: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
Query: 121 DENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
+E R +LE ++ EER + L +LK + + S++ S K E
Sbjct: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+E+++ D++K + + +E E + V K+++ EEK Q EE
Sbjct: 187 EEIKLLSDKLKEAETR-AEFAE--RTVAKLEKTIDDLEEKLAQAKEE 230
Score = 60.5 bits (140), Expect = 7e-09
Identities = 42/205 (20%), Positives = 103/205 (50%), Gaps = 7/205 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A+ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + + +
Sbjct: 51 ALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEM 110
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L++A EE +++ EVA RK+ +E +LE++EER+ ++ K + ++
Sbjct: 111 QLKEAKHIAEEADRKYE----EVA---RKLVILEGELERAEERAEVSELKCGDLEEELKN 163
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
K LE +++ E+ D+ ++K ++A+ +++ R +A +E ++ E++
Sbjct: 164 VTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEK 223
Query: 183 VKSGDAKISELEEELKVVGNSLKSL 207
+ + L + L N L +
Sbjct: 224 LAQAKEENVGLHQTLDQTLNELNCI 248
Score = 48.0 bits (109), Expect = 4e-05
Identities = 35/159 (22%), Positives = 73/159 (45%), Gaps = 6/159 (3%)
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
S + R + L+ +A + E+R L +L R E A+G ++R++ VE+EL+
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXX 238
A++R+ + + +LEE K S + ++V E +A + E+
Sbjct: 66 AQERLATA---LQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEA 122
Query: 239 XXXXXKTVKK---LQKEVDRLEDELGINKDRYKSLADEM 274
+ +K L+ E++R E+ +++ + L +E+
Sbjct: 123 DRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEEL 161
>BC067225-1|AAH67225.1| 248|Homo sapiens tropomyosin 4 protein.
Length = 248
Score = 173 bits (421), Expect = 6e-43
Identities = 89/236 (37%), Positives = 148/236 (62%)
Query: 46 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 105
+++K+ +++ +++ + ++L+ + ++ E +VAALNR++Q +EE+L++++ER
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 69
Query: 106 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 165
TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXX 225
+RKL +E ELE AE+R + + K +LEEELK V N+LKSLE + EK +++ +++
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEI 189
Query: 226 XXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+TV KL+K +D LE++L K+ L +D T EL
Sbjct: 190 KLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNEL 245
Score = 85.8 bits (203), Expect = 2e-16
Identities = 60/227 (26%), Positives = 112/227 (49%), Gaps = 10/227 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+K+K+QA++ + D A D+A +++ R EK +V L +++ VEE+L
Sbjct: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
Query: 121 DENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
+E R +LE ++ EER + L +LK + + S++ S K E
Sbjct: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+E+++ D++K + + +E E + V K+++ EEK Q EE
Sbjct: 187 EEIKLLSDKLKEAETR-AEFAE--RTVAKLEKTIDDLEEKLAQAKEE 230
Score = 60.5 bits (140), Expect = 7e-09
Identities = 42/205 (20%), Positives = 103/205 (50%), Gaps = 7/205 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A+ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + + +
Sbjct: 51 ALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEM 110
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L++A EE +++ EVA RK+ +E +LE++EER+ ++ K + ++
Sbjct: 111 QLKEAKHIAEEADRKYE----EVA---RKLVILEGELERAEERAEVSELKCGDLEEELKN 163
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
K LE +++ E+ D+ ++K ++A+ +++ R +A +E ++ E++
Sbjct: 164 VTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEK 223
Query: 183 VKSGDAKISELEEELKVVGNSLKSL 207
+ + L + L N L +
Sbjct: 224 LAQAKEENVGLHQTLDQTLNELNCI 248
Score = 48.0 bits (109), Expect = 4e-05
Identities = 35/159 (22%), Positives = 73/159 (45%), Gaps = 6/159 (3%)
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
S + R + L+ +A + E+R L +L R E A+G ++R++ VE+EL+
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXX 238
A++R+ + + +LEE K S + ++V E +A + E+
Sbjct: 66 AQERLATA---LQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEA 122
Query: 239 XXXXXKTVKK---LQKEVDRLEDELGINKDRYKSLADEM 274
+ +K L+ E++R E+ +++ + L +E+
Sbjct: 123 DRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEEL 161
>BC037576-1|AAH37576.1| 248|Homo sapiens tropomyosin 4 protein.
Length = 248
Score = 173 bits (421), Expect = 6e-43
Identities = 89/236 (37%), Positives = 148/236 (62%)
Query: 46 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 105
+++K+ +++ +++ + ++L+ + ++ E +VAALNR++Q +EE+L++++ER
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 69
Query: 106 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 165
TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXX 225
+RKL +E ELE AE+R + + K +LEEELK V N+LKSLE + EK +++ +++
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEI 189
Query: 226 XXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+TV KL+K +D LE++L K+ L +D T EL
Sbjct: 190 KLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNEL 245
Score = 85.8 bits (203), Expect = 2e-16
Identities = 60/227 (26%), Positives = 112/227 (49%), Gaps = 10/227 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+K+K+QA++ + D A D+A +++ R EK +V L +++ VEE+L
Sbjct: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
Query: 121 DENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
+E R +LE ++ EER + L +LK + + S++ S K E
Sbjct: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+E+++ D++K + + +E E + V K+++ EEK Q EE
Sbjct: 187 EEIKLLSDKLKEAETR-AEFAE--RTVAKLEKTIDDLEEKLAQAKEE 230
Score = 60.5 bits (140), Expect = 7e-09
Identities = 42/205 (20%), Positives = 103/205 (50%), Gaps = 7/205 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A+ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + + +
Sbjct: 51 ALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEM 110
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L++A EE +++ EVA RK+ +E +LE++EER+ ++ K + ++
Sbjct: 111 QLKEAKHIAEEADRKYE----EVA---RKLVILEGELERAEERAEVSELKCGDLEEELKN 163
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
K LE +++ E+ D+ ++K ++A+ +++ R +A +E ++ E++
Sbjct: 164 VTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEK 223
Query: 183 VKSGDAKISELEEELKVVGNSLKSL 207
+ + L + L N L +
Sbjct: 224 LAQAKEENVGLHQTLDQTLNELNCI 248
Score = 48.0 bits (109), Expect = 4e-05
Identities = 35/159 (22%), Positives = 73/159 (45%), Gaps = 6/159 (3%)
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
S + R + L+ +A + E+R L +L R E A+G ++R++ VE+EL+
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXX 238
A++R+ + + +LEE K S + ++V E +A + E+
Sbjct: 66 AQERLATA---LQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEA 122
Query: 239 XXXXXKTVKK---LQKEVDRLEDELGINKDRYKSLADEM 274
+ +K L+ E++R E+ +++ + L +E+
Sbjct: 123 DRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEEL 161
>M19715-1|AAA61227.1| 229|Homo sapiens TPM1 protein.
Length = 229
Score = 173 bits (420), Expect = 8e-43
Identities = 86/218 (39%), Positives = 142/218 (65%)
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++ADE+
Sbjct: 9 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 68
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE+R
Sbjct: 69 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA 128
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXX 243
+ + ++ +LEE+L+++ +LK+L +E+K +Q+ + +
Sbjct: 129 ELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAE 188
Query: 244 KTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LE+++ K+ S+ +D T EL
Sbjct: 189 RSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 226
Score = 62.5 bits (145), Expect = 2e-09
Identities = 48/202 (23%), Positives = 94/202 (46%), Gaps = 7/202 (3%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 73
E D + +++ A +A +V L +++ VEE+L + +L A + LEE
Sbjct: 1 ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 60
Query: 74 KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
EK +E + + + Q+ EE +E E + A+ +A + +E R ++E+
Sbjct: 61 AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD 120
Query: 134 AQQDEERMDQLTNQLK--EARLLAEDADGKS-----DEVSRKLAFVEDELEVAEDRVKSG 186
++ EER + Q++ E +L D K+ D+ S+K E+E++V D++K
Sbjct: 121 LERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEA 180
Query: 187 DAKISELEEELKVVGNSLKSLE 208
+ + E + + S+ LE
Sbjct: 181 ETRAEFAERSVTKLEKSIDDLE 202
Score = 59.7 bits (138), Expect = 1e-08
Identities = 45/186 (24%), Positives = 101/186 (54%), Gaps = 14/186 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + + +
Sbjct: 32 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEI 91
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEAQ-QS 119
+L++A E+ +++ EVA RK+ IE DLE++EER+ Q + LE Q +
Sbjct: 92 QLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGQVRQLEEQLRI 144
Query: 120 ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
D+ + E++ Q E+R ++ L+++LKEA AE A+ ++ + + +E++
Sbjct: 145 MDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEK 204
Query: 176 LEVAED 181
+ A++
Sbjct: 205 VAHAKE 210
Score = 47.2 bits (107), Expect = 7e-05
Identities = 32/140 (22%), Positives = 62/140 (44%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D ++ M+ ++ +K + E Q ++A AE + + E+ +KL +E DL +
Sbjct: 66 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 125
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
+ E + + + E+QL + + AL + + ++ EE KL EA+ A+
Sbjct: 126 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 185
Query: 122 ENNRMCKVLENRAQQDEERM 141
R LE EE++
Sbjct: 186 FAERSVTKLEKSIDDLEEKV 205
Score = 40.7 bits (91), Expect = 0.006
Identities = 31/149 (20%), Positives = 67/149 (44%), Gaps = 9/149 (6%)
Query: 139 ERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 198
E + +L+ A A DA+ ++R++ VE+EL+ A++R+ + + +LEE K
Sbjct: 7 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATA---LQKLEEAEK 63
Query: 199 VVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKL---QKEVDR 255
S + ++V E +A + E+ + +KL + +++R
Sbjct: 64 AADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLER 123
Query: 256 LEDELGINKDRYKSLADE---MDSTFAEL 281
E+ +++ + + L ++ MD T L
Sbjct: 124 AEERAELSEGQVRQLEEQLRIMDQTLKAL 152
Score = 32.3 bits (70), Expect = 2.0
Identities = 21/104 (20%), Positives = 51/104 (49%), Gaps = 7/104 (6%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ-------KKLAQVE 54
+ + +K+ ++ + + A ++A+ E Q R + +++ ++ L +K + E
Sbjct: 108 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE 167
Query: 55 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED 98
E++ + +KL++A E E+ +T E + L KV +E+
Sbjct: 168 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 211
>AL590431-5|CAH71266.1| 248|Homo sapiens tropomyosin 3 protein.
Length = 248
Score = 173 bits (420), Expect = 8e-43
Identities = 82/239 (34%), Positives = 153/239 (64%)
Query: 43 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 102
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 103 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 163 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFX 222
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+ +++
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 223 XXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LEDEL K +YK++++E+D ++
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDM 245
Score = 76.2 bits (179), Expect = 1e-13
Identities = 48/215 (22%), Positives = 107/215 (49%), Gaps = 7/215 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFVE 173
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K E
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
+E+++ D++K + + E + + ++ LE
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
Score = 68.9 bits (161), Expect = 2e-11
Identities = 55/212 (25%), Positives = 108/212 (50%), Gaps = 21/212 (9%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + L +
Sbjct: 51 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEI 110
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS--- 119
+L++A EE +++ EVA RK+ IE DLE++EER+ A+ + E +
Sbjct: 111 QLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCREMDEQIRL 163
Query: 120 ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
D+N + E + Q E++ ++ LT++LKEA AE A+ R +A +E
Sbjct: 164 MDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAE-------RSVAKLEKT 216
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSL 207
++ ED + + K + EEL N + S+
Sbjct: 217 IDDLEDELYAQKLKYKAISEELDHALNDMTSI 248
>AF474157-1|AAL84570.1| 247|Homo sapiens TPMsk3 protein.
Length = 247
Score = 173 bits (420), Expect = 8e-43
Identities = 82/239 (34%), Positives = 153/239 (64%)
Query: 43 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 102
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 103 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 163 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFX 222
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+ +++
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 223 XXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LEDEL K +YK++++E+D ++
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDM 245
Score = 76.2 bits (179), Expect = 1e-13
Identities = 48/215 (22%), Positives = 107/215 (49%), Gaps = 7/215 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFVE 173
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K E
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
+E+++ D++K + + E + + ++ LE
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
Score = 68.1 bits (159), Expect = 3e-11
Identities = 55/211 (26%), Positives = 107/211 (50%), Gaps = 21/211 (9%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + L +
Sbjct: 51 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEI 110
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS--- 119
+L++A EE +++ EVA RK+ IE DLE++EER+ A+ + E +
Sbjct: 111 QLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCREMDEQIRL 163
Query: 120 ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
D+N + E + Q E++ ++ LT++LKEA AE A+ R +A +E
Sbjct: 164 MDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAE-------RSVAKLEKT 216
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
++ ED + + K + EEL N + S
Sbjct: 217 IDDLEDELYAQKLKYKAISEELDHALNDMTS 247
>BC002827-1|AAH02827.1| 248|Homo sapiens tropomyosin 4 protein.
Length = 248
Score = 172 bits (418), Expect = 1e-42
Identities = 89/236 (37%), Positives = 147/236 (62%)
Query: 46 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 105
+++K+ +++ +++ + ++L+ + ++ E +VAALNR++Q EE+L++++ER
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLFEEELDRAQER 69
Query: 106 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 165
TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXX 225
+RKL +E ELE AE+R + + K +LEEELK V N+LKSLE + EK +++ +++
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEI 189
Query: 226 XXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+TV KL+K +D LE++L K+ L +D T EL
Sbjct: 190 KLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNEL 245
Score = 83.8 bits (198), Expect = 6e-16
Identities = 59/227 (25%), Positives = 111/227 (48%), Gaps = 10/227 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+K+K+QA++ + D A D+A +++ R EK +V L +++ EE+L
Sbjct: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLFEEELDRA 66
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
Query: 121 DENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
+E R +LE ++ EER + L +LK + + S++ S K E
Sbjct: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+E+++ D++K + + +E E + V K+++ EEK Q EE
Sbjct: 187 EEIKLLSDKLKEAETR-AEFAE--RTVAKLEKTIDDLEEKLAQAKEE 230
Score = 60.1 bits (139), Expect = 9e-09
Identities = 42/205 (20%), Positives = 102/205 (49%), Gaps = 7/205 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A+ +++Q + E D A ++ T Q+ +A A++ ++ ++ + + EE + + +
Sbjct: 51 ALNRRIQLFEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEM 110
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L++A EE +++ EVA RK+ +E +LE++EER+ ++ K + ++
Sbjct: 111 QLKEAKHIAEEADRKYE----EVA---RKLVILEGELERAEERAEVSELKCGDLEEELKN 163
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
K LE +++ E+ D+ ++K ++A+ +++ R +A +E ++ E++
Sbjct: 164 VTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEK 223
Query: 183 VKSGDAKISELEEELKVVGNSLKSL 207
+ + L + L N L +
Sbjct: 224 LAQAKEENVGLHQTLDQTLNELNCI 248
Score = 46.0 bits (104), Expect = 2e-04
Identities = 34/159 (21%), Positives = 72/159 (45%), Gaps = 6/159 (3%)
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
S + R + L+ +A + E+R L +L R E A+G ++R++ E+EL+
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLFEEELDR 65
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXX 238
A++R+ + + +LEE K S + ++V E +A + E+
Sbjct: 66 AQERLATA---LQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEA 122
Query: 239 XXXXXKTVKK---LQKEVDRLEDELGINKDRYKSLADEM 274
+ +K L+ E++R E+ +++ + L +E+
Sbjct: 123 DRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEEL 161
>AF474156-1|AAL84569.1| 203|Homo sapiens TPMsk1 protein.
Length = 203
Score = 171 bits (416), Expect = 2e-42
Identities = 83/203 (40%), Positives = 137/203 (67%)
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV 129
D E K ++ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++ADE+ R KV
Sbjct: 1 DHERKLRETTDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKV 60
Query: 130 LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAK 189
+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE+R + + +
Sbjct: 61 IESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQ 120
Query: 190 ISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKL 249
+ +LEE+L+++ +LK+L +E+K +Q+ + + ++V KL
Sbjct: 121 VRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKL 180
Query: 250 QKEVDRLEDELGINKDRYKSLAD 272
+K +D LEDEL K +YK++++
Sbjct: 181 EKSIDDLEDELYAQKLKYKAISE 203
Score = 63.3 bits (147), Expect = 9e-10
Identities = 48/190 (25%), Positives = 102/190 (53%), Gaps = 14/190 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + + +
Sbjct: 18 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEI 77
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEAQ-QS 119
+L++A E+ +++ EVA RK+ IE DLE++EER+ Q + LE Q +
Sbjct: 78 QLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGQVRQLEEQLRI 130
Query: 120 ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
D+ + E++ Q E+R ++ L+++LKEA AE A+ ++ + + +EDE
Sbjct: 131 MDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDE 190
Query: 176 LEVAEDRVKS 185
L + + K+
Sbjct: 191 LYAQKLKYKA 200
Score = 53.2 bits (122), Expect = 1e-06
Identities = 43/195 (22%), Positives = 84/195 (43%), Gaps = 7/195 (3%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 73
+ + + + E N R + V EE+ Q++LA + KLE+A K +E
Sbjct: 1 DHERKLRETTDAEADVASLNRRIQLVEEELDRAQERLATALQ-------KLEEAEKAADE 53
Query: 74 KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
E+ + E+ K++ E L++++ + A +K E + + E R
Sbjct: 54 SERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEER 113
Query: 134 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 193
A+ E ++ QL QL+ + D+ S+K E+E++V D++K + +
Sbjct: 114 AELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFA 173
Query: 194 EEELKVVGNSLKSLE 208
E + + S+ LE
Sbjct: 174 ERSVTKLEKSIDDLE 188
Score = 45.6 bits (103), Expect = 2e-04
Identities = 31/140 (22%), Positives = 61/140 (43%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D ++ M+ ++ +K + E Q ++A AE + + E+ +KL +E DL +
Sbjct: 52 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 111
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
+ E + + + E+QL + + AL + + ++ EE KL EA+ A+
Sbjct: 112 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 171
Query: 122 ENNRMCKVLENRAQQDEERM 141
R LE E+ +
Sbjct: 172 FAERSVTKLEKSIDDLEDEL 191
>DQ424903-1|ABD83668.1| 245|Homo sapiens tropomyosin 1 alpha
variant 6 protein.
Length = 245
Score = 167 bits (406), Expect = 4e-41
Identities = 81/235 (34%), Positives = 148/235 (62%)
Query: 40 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 99
+ + +++K+ ++E + + ++L+ + K EA+VA+LNR++Q +EE+L
Sbjct: 4 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEEL 63
Query: 100 EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 159
++++ER TA QKL EA+++ADE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD
Sbjct: 64 DRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 123
Query: 160 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
K +EV+RKL +E +LE AE+R + + ++ +LEE+L+++ +LK+L +E+K +Q+ +
Sbjct: 124 RKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKED 183
Query: 220 EFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
+ ++V KL+K +D LED+L ++ + L +E+
Sbjct: 184 RYEEEIKVLSDKPKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNEL 238
Score = 73.3 bits (172), Expect = 9e-13
Identities = 51/215 (23%), Positives = 107/215 (49%), Gaps = 7/215 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+++K+++++ + D A ++A T +++ E +V L +++ VEE+L
Sbjct: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + Q+ EE +E E + A+ +A +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLK--EARLLAEDADGKS-----DEVSRKLAFVE 173
+E R ++E+ ++ EER + Q++ E +L D K+ D+ S+K E
Sbjct: 127 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE 186
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
+E++V D+ K + + E + + S+ LE
Sbjct: 187 EEIKVLSDKPKEAETRAEFAERSVTKLEKSIDDLE 221
Score = 61.3 bits (142), Expect = 4e-09
Identities = 47/208 (22%), Positives = 90/208 (43%), Gaps = 9/208 (4%)
Query: 80 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 139
A + + A+ RK++ ++E + +EER+GT Q++L ++ + L R Q EE
Sbjct: 2 AGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEE 61
Query: 140 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELEVAEDRVKSGDAKISE 192
+D+ +L A E+A+ +DE R + + E+++E+ E ++K +
Sbjct: 62 ELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAED 121
Query: 193 LEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKE 252
+ + + V L +E E+A +R E K ++
Sbjct: 122 ADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQK 181
Query: 253 VDRLEDELGINKDRYKSLADEMDSTFAE 280
DR E+E+ + D+ K E + FAE
Sbjct: 182 EDRYEEEIKVLSDKPKEA--ETRAEFAE 207
Score = 60.1 bits (139), Expect = 9e-09
Identities = 48/202 (23%), Positives = 109/202 (53%), Gaps = 16/202 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + + +
Sbjct: 51 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEI 110
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEAQ-QS 119
+L++A E+ +++ EVA RK+ IE DLE++EER+ Q + LE Q +
Sbjct: 111 QLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGQVRQLEEQLRI 163
Query: 120 ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
D+ + E++ Q E+R ++ L+++ KEA AE A+ ++ + + +ED+
Sbjct: 164 MDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKPKEAETRAEFAERSVTKLEKSIDDLEDQ 223
Query: 176 L--EVAEDRVKSGDAKISELEE 195
L ++ ++R + + K++ E+
Sbjct: 224 LYQQLEQNRRLTNELKLALNED 245
Score = 51.6 bits (118), Expect = 3e-06
Identities = 38/174 (21%), Positives = 77/174 (44%), Gaps = 9/174 (5%)
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
+ S + R + L+ +A EER L +L R L E A+ ++R++ VE
Sbjct: 1 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 60
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXX 233
+EL+ A++R+ + + +LEE K S + ++V E +A + E+
Sbjct: 61 EELDRAQERLATA---LQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKH 117
Query: 234 XXXXXXXXXXKTVKKL---QKEVDRLEDELGINKDRYKSLADE---MDSTFAEL 281
+ +KL + +++R E+ +++ + + L ++ MD T L
Sbjct: 118 IAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKAL 171
Score = 49.6 bits (113), Expect = 1e-05
Identities = 36/157 (22%), Positives = 77/157 (49%), Gaps = 7/157 (4%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D ++ M+ ++ +K + E Q ++A AE + + E+ +KL +E DL +
Sbjct: 85 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 144
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEEDLEKSEERSGTAQQKLL 114
+ E + + + E+QL + + AL ++K + EE+++ ++ A+ +
Sbjct: 145 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKPKEAETRAE 204
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA 151
A++S + + LE++ Q E+ +LTN+LK A
Sbjct: 205 FAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLA 241
>Z24727-1|CAA80853.1| 243|Homo sapiens tropomyosin isoform protein.
Length = 243
Score = 167 bits (405), Expect = 5e-41
Identities = 83/213 (38%), Positives = 140/213 (65%)
Query: 54 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
E++L L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL
Sbjct: 17 EDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKL 76
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
EA+++ADE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E
Sbjct: 77 EEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIE 136
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXX 233
+LE AE+R + + ++ +LEE+L+++ +LK+L +E+K +Q+ + +
Sbjct: 137 SDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLK 196
Query: 234 XXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
++V KL+K +D LE+++ + K +
Sbjct: 197 EAETRAEFAERSVTKLEKSIDDLEEKVLMPKKK 229
Score = 58.4 bits (135), Expect = 3e-08
Identities = 44/181 (24%), Positives = 98/181 (54%), Gaps = 14/181 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + + +
Sbjct: 50 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEI 109
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEAQ-QS 119
+L++A E+ +++ EVA RK+ IE DLE++EER+ Q + LE Q +
Sbjct: 110 QLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGQVRQLEEQLRI 162
Query: 120 ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
D+ + E++ Q E+R ++ L+++LKEA AE A+ ++ + + +E++
Sbjct: 163 MDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEK 222
Query: 176 L 176
+
Sbjct: 223 V 223
Score = 47.2 bits (107), Expect = 7e-05
Identities = 32/140 (22%), Positives = 62/140 (44%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D ++ M+ ++ +K + E Q ++A AE + + E+ +KL +E DL +
Sbjct: 84 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 143
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
+ E + + + E+QL + + AL + + ++ EE KL EA+ A+
Sbjct: 144 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 203
Query: 122 ENNRMCKVLENRAQQDEERM 141
R LE EE++
Sbjct: 204 FAERSVTKLEKSIDDLEEKV 223
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/160 (20%), Positives = 71/160 (44%), Gaps = 9/160 (5%)
Query: 128 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 187
K E+ + E + +L+ A A DA+ ++R++ VE+EL+ A++R+ +
Sbjct: 14 KGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATA- 72
Query: 188 AKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVK 247
+ +LEE K S + ++V E +A + E+ + +
Sbjct: 73 --LQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVAR 130
Query: 248 KL---QKEVDRLEDELGINKDRYKSLADE---MDSTFAEL 281
KL + +++R E+ +++ + + L ++ MD T L
Sbjct: 131 KLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKAL 170
Score = 38.3 bits (85), Expect = 0.030
Identities = 36/164 (21%), Positives = 68/164 (41%), Gaps = 6/164 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNE--EVRELQKKLAQ-VEEDL 57
+D ++++ + + A AD E+ + RA+K E E++E+Q K A+ + ED
Sbjct: 62 LDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 121
Query: 58 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
K E+ + L E L E +V+Q+EE L ++ +
Sbjct: 122 ---DRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYS 178
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
Q D KVL ++ ++ E R + + + +D + K
Sbjct: 179 QKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEK 222
Score = 30.3 bits (65), Expect = 8.0
Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 7/96 (7%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLA---QVEEDLILNKNKLEQANKDLEEKEKQLT--A 80
E A RAE +VR+L+++L Q + L+ ++K Q EE+ K L+
Sbjct: 136 ESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKL 195
Query: 81 TEAEVAA--LNRKVQQIEEDLEKSEERSGTAQQKLL 114
EAE A R V ++E+ ++ EE+ ++K L
Sbjct: 196 KEAETRAEFAERSVTKLEKSIDDLEEKVLMPKKKTL 231
>X04588-1|CAB37185.1| 248|Homo sapiens protein ( Human 2.5 kb mRNA
for cytoskeletal tropomyosin TM30(nm). ).
Length = 248
Score = 165 bits (400), Expect = 2e-40
Identities = 80/239 (33%), Positives = 148/239 (61%)
Query: 43 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 102
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 103 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 163 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFX 222
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+ +++
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 223 XXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LED+L K+ + +D T +L
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDL 245
Score = 76.2 bits (179), Expect = 1e-13
Identities = 48/215 (22%), Positives = 107/215 (49%), Gaps = 7/215 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFVE 173
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K E
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
+E+++ D++K + + E + + ++ LE
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
>BC072428-1|AAH72428.1| 248|Homo sapiens tropomyosin 3 protein.
Length = 248
Score = 165 bits (400), Expect = 2e-40
Identities = 80/239 (33%), Positives = 148/239 (61%)
Query: 43 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 102
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 103 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 163 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFX 222
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+ +++
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 223 XXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LED+L K+ + +D T +L
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDL 245
Score = 76.2 bits (179), Expect = 1e-13
Identities = 48/215 (22%), Positives = 107/215 (49%), Gaps = 7/215 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFVE 173
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K E
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
+E+++ D++K + + E + + ++ LE
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
>BC015403-1|AAH15403.1| 248|Homo sapiens tropomyosin 3 protein.
Length = 248
Score = 165 bits (400), Expect = 2e-40
Identities = 80/239 (33%), Positives = 148/239 (61%)
Query: 43 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 102
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 103 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 163 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFX 222
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+ +++
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 223 XXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LED+L K+ + +D T +L
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDL 245
Score = 76.2 bits (179), Expect = 1e-13
Identities = 48/215 (22%), Positives = 107/215 (49%), Gaps = 7/215 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFVE 173
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K E
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
+E+++ D++K + + E + + ++ LE
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
>BC000771-1|AAH00771.1| 248|Homo sapiens tropomyosin 3 protein.
Length = 248
Score = 165 bits (400), Expect = 2e-40
Identities = 80/239 (33%), Positives = 148/239 (61%)
Query: 43 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 102
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 103 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 163 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFX 222
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+ +++
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 223 XXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LED+L K+ + +D T +L
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDL 245
Score = 76.2 bits (179), Expect = 1e-13
Identities = 48/215 (22%), Positives = 107/215 (49%), Gaps = 7/215 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFVE 173
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K E
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
+E+++ D++K + + E + + ++ LE
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
>AL590431-7|CAH71264.1| 248|Homo sapiens tropomyosin 3 protein.
Length = 248
Score = 165 bits (400), Expect = 2e-40
Identities = 80/239 (33%), Positives = 148/239 (61%)
Query: 43 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 102
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 103 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 163 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFX 222
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+ +++
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 223 XXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LED+L K+ + +D T +L
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDL 245
Score = 76.2 bits (179), Expect = 1e-13
Identities = 48/215 (22%), Positives = 107/215 (49%), Gaps = 7/215 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFVE 173
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K E
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
+E+++ D++K + + E + + ++ LE
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
>AY004867-1|AAF87083.1| 247|Homo sapiens tropomyosin isoform
protein.
Length = 247
Score = 163 bits (397), Expect = 5e-40
Identities = 80/239 (33%), Positives = 150/239 (62%)
Query: 43 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 102
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 103 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 163 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFX 222
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+ +++
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 223 XXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LE+ L +R + L++E+ T +L
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
Score = 76.2 bits (179), Expect = 1e-13
Identities = 48/215 (22%), Positives = 107/215 (49%), Gaps = 7/215 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFVE 173
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K E
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
+E+++ D++K + + E + + ++ LE
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/198 (24%), Positives = 106/198 (53%), Gaps = 16/198 (8%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + L +
Sbjct: 51 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEI 110
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS--- 119
+L++A EE +++ EVA RK+ IE DLE++EER+ A+ + E +
Sbjct: 111 QLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCREMDEQIRL 163
Query: 120 ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
D+N + E + Q E++ ++ LT++LKEA AE A+ ++ + + +E+
Sbjct: 164 MDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEER 223
Query: 176 L--EVAEDRVKSGDAKIS 191
L ++ +R+ S + K++
Sbjct: 224 LYSQLERNRLLSNELKLT 241
Score = 32.7 bits (71), Expect = 1.5
Identities = 24/104 (23%), Positives = 54/104 (51%), Gaps = 7/104 (6%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+ + +K+ ++ + + ++A+ E + R+ + + +++ + K L+ EE +
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNL----KCLSAAEEKYSQKE 182
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 105
+K E+ K L +K K+ T AE A R V ++E+ ++ EER
Sbjct: 183 DKYEEEIKILTDKLKE-AETRAEFA--ERSVAKLEKTIDDLEER 223
>X12369-1|CAA30930.1| 227|Homo sapiens tropomyosin (227 AA)
protein.
Length = 227
Score = 163 bits (396), Expect = 6e-40
Identities = 81/215 (37%), Positives = 141/215 (65%), Gaps = 1/215 (0%)
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
+++ L E++ + TA EA+VA+LNR++Q +EE+L++++ER T QKL EA+++ADE+ R
Sbjct: 11 SSEHLHERKLRETA-EADVASLNRRIQLVEEELDRAQERLATVLQKLEEAEKAADESERG 69
Query: 127 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE+R +
Sbjct: 70 MKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS 129
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTV 246
+ ++ +LEE+L+++ + L+S+ +E+K +Q+ + + ++V
Sbjct: 130 EGQVRQLEEQLRIMDSDLESINAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSV 189
Query: 247 KKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
KL+K +D LE+++ K+ S+ +D T EL
Sbjct: 190 TKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 224
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/186 (24%), Positives = 84/186 (45%), Gaps = 7/186 (3%)
Query: 23 DTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATE 82
+T E N R + V EE+ Q++LA V + KLE+A K +E E+ + E
Sbjct: 22 ETAEADVASLNRRIQLVEEELDRAQERLATVLQ-------KLEEAEKAADESERGMKVIE 74
Query: 83 AEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 142
+ K++ E L++++ + A +K E + + E RA+ E ++
Sbjct: 75 SRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVR 134
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 202
QL QL+ E + D+ S+K E+E++V D++K + + E + +
Sbjct: 135 QLEEQLRIMDSDLESINAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEK 194
Query: 203 SLKSLE 208
S+ LE
Sbjct: 195 SIDDLE 200
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/186 (24%), Positives = 100/186 (53%), Gaps = 14/186 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + + +
Sbjct: 30 SLNRRIQLVEEELDRAQERLATVLQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEI 89
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEAQ-QS 119
+L++A E+ +++ EVA RK+ IE DLE++EER+ Q + LE Q +
Sbjct: 90 QLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGQVRQLEEQLRI 142
Query: 120 ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
D + E++ Q E+R ++ L+++LKEA AE A+ ++ + + +E++
Sbjct: 143 MDSDLESINAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEK 202
Query: 176 LEVAED 181
+ A++
Sbjct: 203 VAHAKE 208
Score = 50.4 bits (115), Expect = 7e-06
Identities = 31/140 (22%), Positives = 65/140 (46%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D ++ M+ ++ +K + E Q ++A AE + + E+ +KL +E DL +
Sbjct: 64 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 123
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
+ E + + + E+QL ++++ ++N + + ++ EE KL EA+ A+
Sbjct: 124 ERAELSEGQVRQLEEQLRIMDSDLESINAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 183
Query: 122 ENNRMCKVLENRAQQDEERM 141
R LE EE++
Sbjct: 184 FAERSVTKLEKSIDDLEEKV 203
Score = 34.7 bits (76), Expect = 0.37
Identities = 24/104 (23%), Positives = 51/104 (49%), Gaps = 7/104 (6%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRA-----EKVNEEVRELQKKLAQVE 54
+ + +K+ ++ + + A ++A+ E Q R + LR E +N + +K + E
Sbjct: 106 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDSDLESINAAEDKYSQKEDRYE 165
Query: 55 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED 98
E++ + +KL++A E E+ +T E + L KV +E+
Sbjct: 166 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 209
>AF310722-1|AAK17926.1| 320|Homo sapiens tropomyosin 4-anaplastic
lymphoma kinase fusion protein protein.
Length = 320
Score = 163 bits (395), Expect = 8e-40
Identities = 82/212 (38%), Positives = 137/212 (64%)
Query: 46 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 105
+++K+ +++ +++ + ++L+ + ++ E +VAALNR++Q +EE+L++++ER
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 69
Query: 106 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 165
TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXX 225
+RKL +E ELE AE+R + + K +LEEELK V N+LKSLE + EK +++ +++
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEI 189
Query: 226 XXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLE 257
+TV KL+K +D LE
Sbjct: 190 KLLSDKLKEAETRAEFAERTVAKLEKTIDDLE 221
Score = 85.0 bits (201), Expect = 3e-16
Identities = 55/220 (25%), Positives = 106/220 (48%), Gaps = 7/220 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+K+K+QA++ + D A D+A +++ R EK +V L +++ VEE+L
Sbjct: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
Query: 121 DENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
+E R +LE ++ EER + L +LK + + S++ S K E
Sbjct: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
+E+++ D++K + + E + + ++ LEV K
Sbjct: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEVYRRK 226
Score = 48.0 bits (109), Expect = 4e-05
Identities = 35/159 (22%), Positives = 73/159 (45%), Gaps = 6/159 (3%)
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
S + R + L+ +A + E+R L +L R E A+G ++R++ VE+EL+
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXX 238
A++R+ + + +LEE K S + ++V E +A + E+
Sbjct: 66 AQERLATA---LQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEA 122
Query: 239 XXXXXKTVKK---LQKEVDRLEDELGINKDRYKSLADEM 274
+ +K L+ E++R E+ +++ + L +E+
Sbjct: 123 DRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEEL 161
Score = 36.3 bits (80), Expect = 0.12
Identities = 46/203 (22%), Positives = 78/203 (38%), Gaps = 23/203 (11%)
Query: 99 LEKSEERSGTAQQKLLEAQQSAD--------ENNRMCK------VLENRAQQDEERMDQL 144
LE + + QQ+ EA+ A E R K L R Q EE +D+
Sbjct: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
Query: 145 TNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELEVAEDRVKSGDAKISELEEEL 197
+L A E+A+ +DE R + + E+++E+ E ++K E + +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
Query: 198 KVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLE 257
+ V L LE E+A +R E +K ++ D+ E
Sbjct: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
Query: 258 DELGINKDRYKSLADEMDSTFAE 280
+E+ + D+ K E + FAE
Sbjct: 187 EEIKLLSDKLKEA--ETRAEFAE 207
>AF186109-1|AAG17014.1| 237|Homo sapiens TPM4-ALK fusion
oncoprotein type 2 protein.
Length = 237
Score = 163 bits (395), Expect = 8e-40
Identities = 82/212 (38%), Positives = 137/212 (64%)
Query: 46 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 105
+++K+ +++ +++ + ++L+ + ++ E +VAALNR++Q +EE+L++++ER
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 69
Query: 106 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 165
TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXX 225
+RKL +E ELE AE+R + + K +LEEELK V N+LKSLE + EK +++ +++
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEI 189
Query: 226 XXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLE 257
+TV KL+K +D LE
Sbjct: 190 KLLSDKLKEAETRAEFAERTVAKLEKTIDDLE 221
Score = 85.0 bits (201), Expect = 3e-16
Identities = 55/220 (25%), Positives = 106/220 (48%), Gaps = 7/220 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+K+K+QA++ + D A D+A +++ R EK +V L +++ VEE+L
Sbjct: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
Query: 121 DENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
+E R +LE ++ EER + L +LK + + S++ S K E
Sbjct: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
+E+++ D++K + + E + + ++ LEV K
Sbjct: 187 EEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEVYRRK 226
Score = 48.0 bits (109), Expect = 4e-05
Identities = 35/159 (22%), Positives = 73/159 (45%), Gaps = 6/159 (3%)
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
S + R + L+ +A + E+R L +L R E A+G ++R++ VE+EL+
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXX 238
A++R+ + + +LEE K S + ++V E +A + E+
Sbjct: 66 AQERLATA---LQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEA 122
Query: 239 XXXXXKTVKK---LQKEVDRLEDELGINKDRYKSLADEM 274
+ +K L+ E++R E+ +++ + L +E+
Sbjct: 123 DRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEEL 161
Score = 36.3 bits (80), Expect = 0.12
Identities = 46/203 (22%), Positives = 78/203 (38%), Gaps = 23/203 (11%)
Query: 99 LEKSEERSGTAQQKLLEAQQSAD--------ENNRMCK------VLENRAQQDEERMDQL 144
LE + + QQ+ EA+ A E R K L R Q EE +D+
Sbjct: 7 LEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRA 66
Query: 145 TNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELEVAEDRVKSGDAKISELEEEL 197
+L A E+A+ +DE R + + E+++E+ E ++K E + +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKY 126
Query: 198 KVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLE 257
+ V L LE E+A +R E +K ++ D+ E
Sbjct: 127 EEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYE 186
Query: 258 DELGINKDRYKSLADEMDSTFAE 280
+E+ + D+ K E + FAE
Sbjct: 187 EEIKLLSDKLKEA--ETRAEFAE 207
>DQ120714-1|ABC40673.1| 247|Homo sapiens rcTPM3 protein.
Length = 247
Score = 158 bits (384), Expect = 2e-38
Identities = 79/239 (33%), Positives = 146/239 (61%)
Query: 43 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 102
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L++
Sbjct: 6 IEAVKRKIQVLQQQADDAEERAERLQQEVEGERRARKQAEAEVASLNRRIQLVEEELDRP 65
Query: 103 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
+ER TA QKL EA+++A E+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 66 QERLATALQKLEEAEKAAGESERGMKVIENRALKDEEKMELQELQLKEAKHIAEEADRKY 125
Query: 163 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFX 222
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+ +++
Sbjct: 126 EEVARKLVTIEGDLERTEERAELTESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 185
Query: 223 XXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LED+L K+ + +D T +L
Sbjct: 186 EEIKIFTDKPKEAETCAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDL 244
Score = 70.9 bits (166), Expect = 5e-12
Identities = 48/215 (22%), Positives = 104/215 (48%), Gaps = 7/215 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+K+K+Q ++ + D+A ++A+ +Q+ ++ EV L +++ VEE+L
Sbjct: 6 IEAVKRKIQVLQQQADDAEERAERLQQEVEGERRARKQAEAEVASLNRRIQLVEEELDRP 65
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 QERLATALQKLEEAEKAAGESERGMKVIENRALKDEEKMELQELQLKEAKHIAEEADRKY 125
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFVE 173
+E R +E ++ EER + ++ +E RL+ ++ ++ S+K E
Sbjct: 126 EEVARKLVTIEGDLERTEERAELTESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 185
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
+E+++ D+ K + E + + ++ LE
Sbjct: 186 EEIKIFTDKPKEAETCAEFAERSVAKLEKTIDDLE 220
Score = 58.4 bits (135), Expect = 3e-08
Identities = 43/186 (23%), Positives = 95/186 (51%), Gaps = 14/186 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D ++ T Q+ +A A + ++ ++ + + EE + L +
Sbjct: 50 SLNRRIQLVEEELDRPQERLATALQKLEEAEKAAGESERGMKVIENRALKDEEKMELQEL 109
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS--- 119
+L++A EE +++ EVA RK+ IE DLE++EER+ + + E +
Sbjct: 110 QLKEAKHIAEEADRKYE----EVA---RKLVTIEGDLERTEERAELTESRCREMDEQIRL 162
Query: 120 ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
D+N + E + Q E++ ++ T++ KEA AE A+ ++ + + +ED+
Sbjct: 163 MDQNLKCLSAAEEKYSQKEDKYEEEIKIFTDKPKEAETCAEFAERSVAKLEKTIDDLEDK 222
Query: 176 LEVAED 181
L+ ++
Sbjct: 223 LKCTKE 228
>X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of trk
oncogene. ).
Length = 641
Score = 155 bits (376), Expect = 2e-37
Identities = 74/216 (34%), Positives = 138/216 (63%)
Query: 43 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 102
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 103 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QL+EA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLEEAKHIAEEADRKY 126
Query: 163 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFX 222
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+ +++
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 223 XXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLED 258
++V KL+K +D LED
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLED 222
Score = 78.6 bits (185), Expect = 2e-14
Identities = 50/227 (22%), Positives = 112/227 (49%), Gaps = 7/227 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLEEAKHIAEEADRKY 126
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFVE 173
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K E
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+E+++ D++K + + E + + ++ LE + + VE+
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDTNSTSGDPVEK 233
Score = 68.5 bits (160), Expect = 2e-11
Identities = 50/192 (26%), Positives = 100/192 (52%), Gaps = 14/192 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE + L +
Sbjct: 51 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEI 110
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS--- 119
+LE+A EE +++ EVA RK+ IE DLE++EER+ A+ + E +
Sbjct: 111 QLEEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCREMDEQIRL 163
Query: 120 ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
D+N + E + Q E++ ++ LT++LKEA AE A+ ++ + + +ED
Sbjct: 164 MDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDT 223
Query: 176 LEVAEDRVKSGD 187
+ D V+ D
Sbjct: 224 NSTSGDPVEKKD 235
>AL590431-6|CAH71263.1| 224|Homo sapiens tropomyosin 3 protein.
Length = 224
Score = 135 bits (326), Expect = 2e-31
Identities = 72/205 (35%), Positives = 121/205 (59%), Gaps = 1/205 (0%)
Query: 77 QLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ 136
Q A +AE A R +++E + E+R TA QKL EA+++ADE+ R KV+ENRA +
Sbjct: 18 QQQADDAEERA-ERLQREVEGERRAREQRLATALQKLEEAEKAADESERGMKVIENRALK 76
Query: 137 DEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 196
DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E+R + +++ E++E+
Sbjct: 77 DEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQ 136
Query: 197 LKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRL 256
++++ +LK L +EEK +Q+ +++ ++V KL+K +D L
Sbjct: 137 IRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDL 196
Query: 257 EDELGINKDRYKSLADEMDSTFAEL 281
ED+L K+ + +D T +L
Sbjct: 197 EDKLKCTKEEHLCTQRMLDQTLLDL 221
Score = 66.9 bits (156), Expect = 8e-11
Identities = 47/199 (23%), Positives = 104/199 (52%), Gaps = 18/199 (9%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTC------EQQARDANL-----RAEKVNEEVRELQKK 49
++A+K+K+Q ++ + D+A ++A+ E++AR+ L + E+ + E ++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQRLATALQKLEEAEKAADESERG 66
Query: 50 LAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 109
+ +E + ++ K+E L+E + + + + RK+ IE DLE++EER+ A
Sbjct: 67 MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELA 126
Query: 110 QQKLLEAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKS 162
+ + E + D+N + E + Q E++ ++ LT++LKEA AE A+
Sbjct: 127 ESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSV 186
Query: 163 DEVSRKLAFVEDELEVAED 181
++ + + +ED+L+ ++
Sbjct: 187 AKLEKTIDDLEDKLKCTKE 205
Score = 60.5 bits (140), Expect = 7e-09
Identities = 48/205 (23%), Positives = 95/205 (46%), Gaps = 11/205 (5%)
Query: 21 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 80
K +QQA DA RAE++ EV E +++ E+ L KLE+A K +E E+ +
Sbjct: 13 KIQVLQQQADDAEERAERLQREV-EGERRAR--EQRLATALQKLEEAEKAADESERGMKV 69
Query: 81 TEAEVAALNRKVQQIEEDL-------EKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
E K++ E L E+++ + +KL+ + + ++ E+R
Sbjct: 70 IENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESR 129
Query: 134 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 193
++ +E++ + LK E K D+ ++ + D+L+ AE R + + +++L
Sbjct: 130 CREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKL 189
Query: 194 EEELKVVGNSLKSLEVSEEKANQRV 218
E+ + + + LK + E QR+
Sbjct: 190 EKTIDDLEDKLKCTK-EEHLCTQRM 213
>AK129882-1|BAC85248.1| 217|Homo sapiens protein ( Homo sapiens
cDNA FLJ26372 fis, clone HRT06233. ).
Length = 217
Score = 134 bits (324), Expect = 3e-31
Identities = 78/217 (35%), Positives = 126/217 (58%), Gaps = 16/217 (7%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
MDAIKKKMQ +KL+K+NA+D+A+ E + A R++++ +E+ LQKKL E++L
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+ S
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAELS- 119
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
E + + EE + +TN LK AE K D ++ + D+L+ AE
Sbjct: 120 ----------EGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAE 169
Query: 181 DRVKSGDAKISELEEEL-----KVVGNSLKSLEVSEE 212
R + + +++LE+ + ++ LK +SEE
Sbjct: 170 TRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEE 206
Score = 91.1 bits (216), Expect = 4e-18
Identities = 59/212 (27%), Positives = 110/212 (51%), Gaps = 17/212 (8%)
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
A+ +K+Q ++ D E + +R+ A+ A+ + + L+ + + E+ +D+ +
Sbjct: 3 AIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
Query: 147 QLKEARL---LAE----DADGKSDEVSRKLAFVEDELEVAEDRVKSG----------DAK 189
LK+A+ LAE DA+ ++R++ VE+EL+ A++R+ + + K
Sbjct: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAELSEGK 122
Query: 190 ISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKL 249
+ELEEELK V N+LKSLE EK +Q+ + + ++V KL
Sbjct: 123 CAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKL 182
Query: 250 QKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+K +D LEDEL K +YK++++E+D ++
Sbjct: 183 EKSIDDLEDELYAQKLKYKAISEELDHALNDM 214
Score = 32.3 bits (70), Expect = 2.0
Identities = 29/148 (19%), Positives = 60/148 (40%), Gaps = 5/148 (3%)
Query: 141 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 200
MD + +++ +L E+A ++++ ED + ED + S K+ E+EL
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 201 GNSLK----SLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRL 256
+LK LE++E+KA + ++KL+ E +
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLE-EAELS 119
Query: 257 EDELGINKDRYKSLADEMDSTFAELAGY 284
E + ++ K++ + + S A+ Y
Sbjct: 120 EGKCAELEEELKTVTNNLKSLEAQAEKY 147
>AL590431-8|CAH71265.1| 232|Homo sapiens tropomyosin 3 protein.
Length = 232
Score = 129 bits (312), Expect = 9e-30
Identities = 70/239 (29%), Positives = 136/239 (56%), Gaps = 16/239 (6%)
Query: 43 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 102
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 103 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
+ER TA QKL EA+++ADE ++M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADE----------------KKMELQEIQLKEAKHIAEEADRKY 110
Query: 163 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFX 222
+EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+ +++
Sbjct: 111 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 170
Query: 223 XXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LED+L K+ + +D T +L
Sbjct: 171 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDL 229
Score = 79.4 bits (187), Expect = 1e-14
Identities = 47/218 (21%), Positives = 111/218 (50%), Gaps = 3/218 (1%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L A + LEE EK A E ++ ++++ + E+++ + +KL+ +
Sbjct: 67 QERLATALQKLEEAEK--AADEKKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDL 124
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ ++ E+R ++ +E++ + LK E K D+ ++ + D+L+ AE
Sbjct: 125 ERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAE 184
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
R + + +++LE+ + + + LK + E QR+
Sbjct: 185 TRAEFAERSVAKLEKTIDDLEDKLKCTK-EEHLCTQRM 221
>BC062740-1|AAH62740.1| 158|Homo sapiens TPM3 protein protein.
Length = 158
Score = 125 bits (302), Expect = 2e-28
Identities = 64/154 (41%), Positives = 97/154 (62%)
Query: 128 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 187
KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E+R + +
Sbjct: 2 KVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAE 61
Query: 188 AKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVK 247
+K SELEEELK V N+LKSLE EK +Q+ +++ ++V
Sbjct: 62 SKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVA 121
Query: 248 KLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
KL+K +D LEDEL K +YK++++E+D ++
Sbjct: 122 KLEKTIDDLEDELYAQKLKYKAISEELDHALNDM 155
Score = 58.8 bits (136), Expect = 2e-08
Identities = 36/155 (23%), Positives = 76/155 (49%)
Query: 53 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
+E + ++ K+E L+E + + + + RK+ IE DLE++EER+ A+ K
Sbjct: 4 IENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESK 63
Query: 113 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 172
E ++ K LE +A++ ++ D+ ++K ++A+ +++ R +A +
Sbjct: 64 CSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKL 123
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSL 207
E ++ ED + + K + EEL N + S+
Sbjct: 124 EKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 158
Score = 47.6 bits (108), Expect = 5e-05
Identities = 29/143 (20%), Positives = 67/143 (46%), Gaps = 5/143 (3%)
Query: 75 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRA 134
E + E ++ ++++ + E+++ + +KL+ + + ++ E++
Sbjct: 5 ENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKC 64
Query: 135 QQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 194
+ EE + +TN LK AE K D+ ++ + D+L+ AE R + + +++LE
Sbjct: 65 SELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLE 124
Query: 195 E-----ELKVVGNSLKSLEVSEE 212
+ E ++ LK +SEE
Sbjct: 125 KTIDDLEDELYAQKLKYKAISEE 147
Score = 41.5 bits (93), Expect = 0.003
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 7/124 (5%)
Query: 95 IEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 154
IE K EE+ + +L EA+ A+E +R + ++ ++ + L+
Sbjct: 4 IENRALKDEEKMELQEIQLKEAKHIAEEADR-------KYEEVARKLVIIEGDLERTEER 56
Query: 155 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
AE A+ K E+ +L V + L+ E + + K + EEE+K++ + LK E E A
Sbjct: 57 AELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFA 116
Query: 215 NQRV 218
+ V
Sbjct: 117 ERSV 120
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/123 (18%), Positives = 60/123 (48%)
Query: 29 ARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL 88
A +A+ + E+V ++ ++ L + EE L ++K + ++L+ L + EA+
Sbjct: 29 AEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKY 88
Query: 89 NRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL 148
++K + EE+++ ++ A+ + A++S + + LE+ + + ++ +L
Sbjct: 89 SQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEEL 148
Query: 149 KEA 151
A
Sbjct: 149 DHA 151
Score = 31.1 bits (67), Expect = 4.6
Identities = 14/80 (17%), Positives = 40/80 (50%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +++ + + ++D ++ + ++A RAE V +L+K + +E++L
Sbjct: 78 LKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQ 137
Query: 61 KNKLEQANKDLEEKEKQLTA 80
K K + +++L+ +T+
Sbjct: 138 KLKYKAISEELDHALNDMTS 157
>AL590431-4|CAH71262.1| 158|Homo sapiens tropomyosin 3 protein.
Length = 158
Score = 125 bits (302), Expect = 2e-28
Identities = 64/154 (41%), Positives = 97/154 (62%)
Query: 128 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 187
KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E+R + +
Sbjct: 2 KVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAE 61
Query: 188 AKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVK 247
+K SELEEELK V N+LKSLE EK +Q+ +++ ++V
Sbjct: 62 SKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVA 121
Query: 248 KLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
KL+K +D LEDEL K +YK++++E+D ++
Sbjct: 122 KLEKTIDDLEDELYAQKLKYKAISEELDHALNDM 155
Score = 58.8 bits (136), Expect = 2e-08
Identities = 36/155 (23%), Positives = 76/155 (49%)
Query: 53 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
+E + ++ K+E L+E + + + + RK+ IE DLE++EER+ A+ K
Sbjct: 4 IENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESK 63
Query: 113 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 172
E ++ K LE +A++ ++ D+ ++K ++A+ +++ R +A +
Sbjct: 64 CSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKL 123
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSL 207
E ++ ED + + K + EEL N + S+
Sbjct: 124 EKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 158
Score = 47.6 bits (108), Expect = 5e-05
Identities = 29/143 (20%), Positives = 67/143 (46%), Gaps = 5/143 (3%)
Query: 75 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRA 134
E + E ++ ++++ + E+++ + +KL+ + + ++ E++
Sbjct: 5 ENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKC 64
Query: 135 QQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 194
+ EE + +TN LK AE K D+ ++ + D+L+ AE R + + +++LE
Sbjct: 65 SELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLE 124
Query: 195 E-----ELKVVGNSLKSLEVSEE 212
+ E ++ LK +SEE
Sbjct: 125 KTIDDLEDELYAQKLKYKAISEE 147
Score = 41.5 bits (93), Expect = 0.003
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 7/124 (5%)
Query: 95 IEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 154
IE K EE+ + +L EA+ A+E +R + ++ ++ + L+
Sbjct: 4 IENRALKDEEKMELQEIQLKEAKHIAEEADR-------KYEEVARKLVIIEGDLERTEER 56
Query: 155 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
AE A+ K E+ +L V + L+ E + + K + EEE+K++ + LK E E A
Sbjct: 57 AELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFA 116
Query: 215 NQRV 218
+ V
Sbjct: 117 ERSV 120
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/123 (18%), Positives = 60/123 (48%)
Query: 29 ARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL 88
A +A+ + E+V ++ ++ L + EE L ++K + ++L+ L + EA+
Sbjct: 29 AEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKY 88
Query: 89 NRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL 148
++K + EE+++ ++ A+ + A++S + + LE+ + + ++ +L
Sbjct: 89 SQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEEL 148
Query: 149 KEA 151
A
Sbjct: 149 DHA 151
Score = 31.1 bits (67), Expect = 4.6
Identities = 14/80 (17%), Positives = 40/80 (50%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +++ + + ++D ++ + ++A RAE V +L+K + +E++L
Sbjct: 78 LKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQ 137
Query: 61 KNKLEQANKDLEEKEKQLTA 80
K K + +++L+ +T+
Sbjct: 138 KLKYKAISEELDHALNDMTS 157
>AL590431-3|CAH71261.1| 158|Homo sapiens tropomyosin 3 protein.
Length = 158
Score = 117 bits (282), Expect = 4e-26
Identities = 62/154 (40%), Positives = 92/154 (59%)
Query: 128 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 187
KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E+R + +
Sbjct: 2 KVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAE 61
Query: 188 AKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVK 247
+K SELEEELK V N+LKSLE EK +Q+ +++ ++V
Sbjct: 62 SKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVA 121
Query: 248 KLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
KL+K +D LED+L K+ + +D T +L
Sbjct: 122 KLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDL 155
Score = 54.0 bits (124), Expect = 6e-07
Identities = 31/132 (23%), Positives = 68/132 (51%)
Query: 53 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
+E + ++ K+E L+E + + + + RK+ IE DLE++EER+ A+ K
Sbjct: 4 IENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESK 63
Query: 113 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 172
E ++ K LE +A++ ++ D+ ++K ++A+ +++ R +A +
Sbjct: 64 CSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKL 123
Query: 173 EDELEVAEDRVK 184
E ++ ED++K
Sbjct: 124 EKTIDDLEDKLK 135
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/144 (19%), Positives = 68/144 (47%), Gaps = 1/144 (0%)
Query: 75 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRA 134
E + E ++ ++++ + E+++ + +KL+ + + ++ E++
Sbjct: 5 ENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKC 64
Query: 135 QQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 194
+ EE + +TN LK AE K D+ ++ + D+L+ AE R + + +++LE
Sbjct: 65 SELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLE 124
Query: 195 EELKVVGNSLKSLEVSEEKANQRV 218
+ + + + LK + E QR+
Sbjct: 125 KTIDDLEDKLKCTK-EEHLCTQRM 147
Score = 41.5 bits (93), Expect = 0.003
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 7/124 (5%)
Query: 95 IEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 154
IE K EE+ + +L EA+ A+E +R + ++ ++ + L+
Sbjct: 4 IENRALKDEEKMELQEIQLKEAKHIAEEADR-------KYEEVARKLVIIEGDLERTEER 56
Query: 155 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
AE A+ K E+ +L V + L+ E + + K + EEE+K++ + LK E E A
Sbjct: 57 AELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFA 116
Query: 215 NQRV 218
+ V
Sbjct: 117 ERSV 120
Score = 35.9 bits (79), Expect = 0.16
Identities = 26/129 (20%), Positives = 62/129 (48%), Gaps = 7/129 (5%)
Query: 29 ARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL 88
A +A+ + E+V ++ ++ L + EE L ++K + ++L+ L + EA+
Sbjct: 29 AEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKY 88
Query: 89 NRKVQQIEED-------LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
++K + EE+ L+++E R+ A++ + + +++ D+ K + + +
Sbjct: 89 SQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRML 148
Query: 142 DQLTNQLKE 150
DQ L E
Sbjct: 149 DQTLLDLNE 157
Score = 35.5 bits (78), Expect = 0.21
Identities = 37/143 (25%), Positives = 65/143 (45%), Gaps = 15/143 (10%)
Query: 40 NEEVRELQK-KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED 98
+EE ELQ+ +L + + K E+ + L E L TE K ++EE+
Sbjct: 11 DEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEE 70
Query: 99 LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA 158
L ++ T K LEAQ + + + EE + LT++LKEA AE A
Sbjct: 71 L-----KNVTNNLKSLEAQ---------AEKYSQKEDKYEEEIKILTDKLKEAETRAEFA 116
Query: 159 DGKSDEVSRKLAFVEDELEVAED 181
+ ++ + + +ED+L+ ++
Sbjct: 117 ERSVAKLEKTIDDLEDKLKCTKE 139
>AF186110-1|AAG17015.1| 227|Homo sapiens TPM4-ALK fusion
oncoprotein type 1 protein.
Length = 227
Score = 107 bits (257), Expect = 4e-23
Identities = 56/130 (43%), Positives = 81/130 (62%)
Query: 128 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 187
KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E ELE AE+R + +
Sbjct: 2 KVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSE 61
Query: 188 AKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVK 247
K +LEEELK V N+LKSLE + EK +++ +++ +TV
Sbjct: 62 LKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVA 121
Query: 248 KLQKEVDRLE 257
KL+K +D LE
Sbjct: 122 KLEKTIDDLE 131
Score = 43.2 bits (97), Expect = 0.001
Identities = 31/145 (21%), Positives = 71/145 (48%), Gaps = 3/145 (2%)
Query: 53 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
+E + ++ K+E L+E + + + + RK+ +E +LE++EER+ ++ K
Sbjct: 4 IENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELK 63
Query: 113 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 172
+ ++ K LE +++ E+ D+ ++K ++A+ +++ R +A +
Sbjct: 64 CGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKL 123
Query: 173 E---DELEVAEDRVKSGDAKISELE 194
E D+LEV + + A EL+
Sbjct: 124 EKTIDDLEVYRRKHQELQAMQMELQ 148
Score = 43.2 bits (97), Expect = 0.001
Identities = 23/123 (18%), Positives = 57/123 (46%)
Query: 75 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRA 134
E + E ++ ++++ + E+++ + +KL+ + + +V E +
Sbjct: 5 ENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKC 64
Query: 135 QQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 194
EE + +TN LK +E K D+ ++ + D+L+ AE R + + +++LE
Sbjct: 65 GDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLE 124
Query: 195 EEL 197
+ +
Sbjct: 125 KTI 127
Score = 40.7 bits (91), Expect = 0.006
Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 95 IEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 154
IE K EE+ + +L EA+ A+E +R + ++ ++ L +L+ A
Sbjct: 4 IENRAMKDEEKMEIQEMQLKEAKHIAEEADR-------KYEEVARKLVILEGELERAEER 56
Query: 155 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
AE ++ K ++ +L V + L+ E + K + EEE+K++ + LK E E A
Sbjct: 57 AEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFA 116
Query: 215 NQRV 218
+ V
Sbjct: 117 ERTV 120
Score = 39.5 bits (88), Expect = 0.013
Identities = 29/133 (21%), Positives = 58/133 (43%), Gaps = 7/133 (5%)
Query: 88 LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD----- 142
+ + + EE +E E + A+ EA + +E R +LE ++ EER +
Sbjct: 4 IENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELK 63
Query: 143 --QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 200
L +LK + + S++ S K E+E+++ D++K + + E + +
Sbjct: 64 CGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKL 123
Query: 201 GNSLKSLEVSEEK 213
++ LEV K
Sbjct: 124 EKTIDDLEVYRRK 136
>AK092712-1|BAC03956.1| 183|Homo sapiens protein ( Homo sapiens
cDNA FLJ35393 fis, clone SKNSH2000971, highly similar to
TROPOMYOSIN, CYTOSKELETAL TYPE. ).
Length = 183
Score = 95.9 bits (228), Expect = 1e-19
Identities = 48/172 (27%), Positives = 95/172 (55%), Gaps = 2/172 (1%)
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
++K+ QQ AD+ + L+ + ++ + ++ QLKEA+ +AE+AD K +EV+RKL
Sbjct: 11 KRKIQVLQQQADDAEERAERLQREVEGEKMELQEI--QLKEAKHIAEEADRKYEEVARKL 68
Query: 170 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXX 229
+E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+ +++
Sbjct: 69 VIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILT 128
Query: 230 XXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++V KL+K +D LED+L K+ + +D T +L
Sbjct: 129 DKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDL 180
Score = 57.6 bits (133), Expect = 5e-08
Identities = 48/168 (28%), Positives = 87/168 (51%), Gaps = 23/168 (13%)
Query: 21 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 80
K +QQA DA RAE++ EV + +L +++ L++A EE +++
Sbjct: 13 KIQVLQQQADDAEERAERLQREVEGEKMELQEIQ---------LKEAKHIAEEADRKYE- 62
Query: 81 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS---ADENNRMCKVLENRAQQD 137
EVA RK+ IE DLE++EER+ A+ + E + D+N + E + Q
Sbjct: 63 ---EVA---RKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQK 116
Query: 138 EERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E++ ++ LT++LKEA AE A+ ++ + + +ED+L+ ++
Sbjct: 117 EDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKE 164
Score = 46.4 bits (105), Expect = 1e-04
Identities = 32/157 (20%), Positives = 75/157 (47%), Gaps = 3/157 (1%)
Query: 64 LEQANKDLEEKEKQLTA-TEAEVAALNR-KVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
L+Q D EE+ ++L E E L ++++ + E+++ + +KL+ + +
Sbjct: 17 LQQQADDAEERAERLQREVEGEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE 76
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
++ E+R ++ +E++ + LK E K D+ ++ + D+L+ AE
Sbjct: 77 RTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAET 136
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
R + + +++LE+ + + + LK + E QR+
Sbjct: 137 RAEFAERSVAKLEKTIDDLEDKLKCTK-EEHLCTQRM 172
>M12126-1|AAA61229.1| 131|Homo sapiens TPM2 protein.
Length = 131
Score = 94.7 bits (225), Expect = 3e-19
Identities = 45/128 (35%), Positives = 78/128 (60%)
Query: 154 LAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
+AED+D K +EV+RKL +E ELE +E+R + ++K +LEEELK+V N+LKSLE +K
Sbjct: 1 IAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADK 60
Query: 214 ANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADE 273
+ + +++ ++V KL+K +D LEDE+ K +YK++++E
Sbjct: 61 YSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEE 120
Query: 274 MDSTFAEL 281
+D+ ++
Sbjct: 121 LDNALNDI 128
Score = 50.0 bits (114), Expect = 9e-06
Identities = 31/118 (26%), Positives = 59/118 (50%)
Query: 90 RKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK 149
RK+ +E +LE+SEER+ A+ K + ++ K LE +A + + D+ ++K
Sbjct: 14 RKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIK 73
Query: 150 EARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSL 207
++A+ +++ R +A +E ++ ED V + K + EEL N + SL
Sbjct: 74 LLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL 131
Score = 46.8 bits (106), Expect = 9e-05
Identities = 29/121 (23%), Positives = 58/121 (47%), Gaps = 5/121 (4%)
Query: 100 EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 159
E S+ + +KL+ + + + +V E++ EE + +TN LK A+
Sbjct: 3 EDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYS 62
Query: 160 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE-----ELKVVGNSLKSLEVSEEKA 214
K D+ ++ +E++L+ AE R + + +++LE+ E +V +K +SEE
Sbjct: 63 TKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELD 122
Query: 215 N 215
N
Sbjct: 123 N 123
Score = 36.7 bits (81), Expect = 0.092
Identities = 25/123 (20%), Positives = 60/123 (48%)
Query: 29 ARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL 88
A D++ + E+V ++ L+ +L + EE + ++K ++L+ L + EA+
Sbjct: 2 AEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKY 61
Query: 89 NRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL 148
+ K + EE+++ EE+ A+ + A++S + + LE+ + + ++ +L
Sbjct: 62 STKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEEL 121
Query: 149 KEA 151
A
Sbjct: 122 DNA 124
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/80 (17%), Positives = 41/80 (51%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +++ + ++D ++ E++ ++A RAE V +L+K + +E+++
Sbjct: 51 LKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQ 110
Query: 61 KNKLEQANKDLEEKEKQLTA 80
K K + +++L+ +T+
Sbjct: 111 KMKYKAISEELDNALNDITS 130
>M12127-1|AAA36774.1| 131|Homo sapiens protein ( Human cytoskeletal
tropomyosin isoform (3.0 kb) mRNA, 3' end. ).
Length = 131
Score = 90.2 bits (214), Expect = 7e-18
Identities = 47/128 (36%), Positives = 73/128 (57%)
Query: 154 LAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
+AE+AD K +EV+RKL +E ELE AE+R + ++K +LEEEL+ V N+LKSLE + EK
Sbjct: 1 IAEEADRKYEEVARKLVILEGELERAEERAEVSESKCGDLEEELRTVTNNLKSLEAASEK 60
Query: 214 ANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADE 273
+++ +++ +TV KL+K +D LE++L K+ L
Sbjct: 61 YSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQT 120
Query: 274 MDSTFAEL 281
+D T EL
Sbjct: 121 LDQTLNEL 128
Score = 42.7 bits (96), Expect = 0.001
Identities = 23/121 (19%), Positives = 56/121 (46%)
Query: 100 EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 159
E+++ + +KL+ + + +V E++ EE + +TN LK +E
Sbjct: 3 EEADRKYEEVARKLVILEGELERAEERAEVSESKCGDLEEELRTVTNNLKSLEAASEKYS 62
Query: 160 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
K D+ ++ + D+L+ AE R + + +++LE+ + + L + +Q ++
Sbjct: 63 EKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLD 122
Query: 220 E 220
+
Sbjct: 123 Q 123
Score = 39.1 bits (87), Expect = 0.017
Identities = 26/108 (24%), Positives = 48/108 (44%)
Query: 36 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI 95
AE+ + + E+ +KL +E +L + + E + + E++L + +L ++
Sbjct: 2 AEEADRKYEEVARKLVILEGELERAEERAEVSESKCGDLEEELRTVTNNLKSLEAASEKY 61
Query: 96 EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQ 143
E +K EE KL EA+ A+ R LE EE++ Q
Sbjct: 62 SEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQ 109
Score = 39.1 bits (87), Expect = 0.017
Identities = 24/118 (20%), Positives = 58/118 (49%)
Query: 90 RKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK 149
RK+ +E +LE++EER+ ++ K + ++ K LE +++ E+ D+ ++K
Sbjct: 14 RKLVILEGELERAEERAEVSESKCGDLEEELRTVTNNLKSLEAASEKYSEKEDKYEEEIK 73
Query: 150 EARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSL 207
++A+ +++ R +A +E ++ E+++ + L + L N L +
Sbjct: 74 LLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI 131
>D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heavy
chain protein.
Length = 1052
Score = 76.6 bits (180), Expect = 9e-14
Identities = 59/255 (23%), Positives = 117/255 (45%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ R+LQ++L + E +L +N+ A ++ E L E +
Sbjct: 689 QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERNERALAAAAKKKLEGDLKDLELQAD 748
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+ + ++ + L K + + Q++L +A+ S DE K E +A+ E + QL
Sbjct: 749 SAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE 808
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
L A + AD + +E++ +LA +D + +A+I++LEEEL+ ++++
Sbjct: 809 DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA 868
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
+ KA Q+ E+ + K+L+ ++ +E G K +
Sbjct: 869 MSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEME---GAVKSK 925
Query: 267 YKSLADEMDSTFAEL 281
+KS +++ A+L
Sbjct: 926 FKSTIAALEAKIAQL 940
Score = 65.3 bits (152), Expect = 2e-10
Identities = 59/291 (20%), Positives = 124/291 (42%), Gaps = 11/291 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQVEEDLILN 60
+AIK+ + KD + D + +RD K NE+ + L+ L Q++EDL
Sbjct: 756 EAIKQLRKLQAQMKDFQRELEDA--RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 813
Query: 61 KNKLEQANKDLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
+ +QA+ + EE ++L A + E L ++ Q+EE+LE+ + ++
Sbjct: 814 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 873
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK-SDEVSRKLAFV 172
+A Q A++ + + AQ++E QL Q KE R + +G + +A +
Sbjct: 874 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAAL 933
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXX 232
E ++ E++V+ + + LK LK + + E + E++
Sbjct: 934 EAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARV 993
Query: 233 XXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAG 283
+ +++ +L+ EL + +++ E+++ ++L G
Sbjct: 994 KQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRG 1044
Score = 60.1 bits (139), Expect = 9e-09
Identities = 54/293 (18%), Positives = 131/293 (44%), Gaps = 21/293 (7%)
Query: 3 AIKKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 58
A KKK++ ++L+ D+A+ + +Q R + + E+ + + ++
Sbjct: 731 AAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAK 790
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------EERSGTAQQ 111
N+ K + DL + ++ L A E + + +++ E+L S ++ +
Sbjct: 791 ENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEA 850
Query: 112 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
++ + ++ +E + + +R ++ ++ +QL+N+L R A+ + ++ R+
Sbjct: 851 RIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE 910
Query: 172 VEDELEVAEDRVKSG--------DAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXX 223
+ +L E VKS +AKI++LEE+++ ++ S ++ +++++E
Sbjct: 911 LRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILL 970
Query: 224 XXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE-LGINKDRYKSLADEMD 275
VK+L+++++ E+E IN +R K L E+D
Sbjct: 971 QVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRK-LQRELD 1022
Score = 59.3 bits (137), Expect = 2e-08
Identities = 64/284 (22%), Positives = 121/284 (42%), Gaps = 25/284 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL- 59
+ A +KKM L+ + ++ E++A L+ EKV E K+ ++E+++++
Sbjct: 55 LQAERKKMAQQMLDLEEQLE-----EEEAARQKLQLEKVTAEA-----KIKKLEDEILVM 104
Query: 60 --NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
NKL + K LEE+ LT AE K + + + K E + +L + +
Sbjct: 105 DDQNNKLSKERKLLEERISDLTTNLAEE---EEKAKNLTKLKNKHESMISELEVRLKKEE 161
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAEDADGKSDEVSRKLAFVEDEL 176
+S E ++ + LE A E++ L Q+ E ++ LA+ K +E+ LA ++DE+
Sbjct: 162 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK----KEEELQAALARLDDEI 217
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXX 236
+ +K KI ELE + + L S + KA ++ +
Sbjct: 218 AQKNNALK----KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 273
Query: 237 XXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
+ K ++EV L+ L +++ EM A+
Sbjct: 274 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQ 317
Score = 53.6 bits (123), Expect = 8e-07
Identities = 49/264 (18%), Positives = 108/264 (40%), Gaps = 12/264 (4%)
Query: 9 QAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQAN 68
+A+KL KD A + Q +D ++ + + KL Q+EE+ +++L++
Sbjct: 416 KAIKLAKDVA-----SLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 470
Query: 69 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
+ + E+ ++ +++ +K+Q +E EE Q+++ Q +E
Sbjct: 471 EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD 530
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE-------DELEVAED 181
LE + ++ +D L L R L + + K + + LA + DE + AE
Sbjct: 531 KLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEA 590
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXX 241
+ + K L L+ + + LE + + +E+
Sbjct: 591 EAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRA 650
Query: 242 XXKTVKKLQKEVDRLEDELGINKD 265
+++++ +++ LEDEL ++D
Sbjct: 651 LETQMEEMKTQLEELEDELQASED 674
Score = 52.4 bits (120), Expect = 2e-06
Identities = 48/272 (17%), Positives = 125/272 (45%), Gaps = 28/272 (10%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQ----QARDANLRAEKVNEEVR-------ELQKKLAQVE 54
++++A+K E ++ +D T ++ + ++ + + ++EE R E+++K AQ
Sbjct: 260 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 319
Query: 55 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
E+L + ++A +L++ ++ L A++A R + Q ++++E ++K L
Sbjct: 320 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEH--------KKKKL 371
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
EAQ E C E + +++ +L N+++ + +A+GK+ ++++ +A +
Sbjct: 372 EAQ--VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 429
Query: 175 ELEVAEDRVK-------SGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXX 227
+L+ ++ ++ + K+ +LEEE + + L +++ + +
Sbjct: 430 QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 489
Query: 228 XXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE 259
+ K+ QKE++ L +
Sbjct: 490 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 521
Score = 50.8 bits (116), Expect = 5e-06
Identities = 37/217 (17%), Positives = 92/217 (42%), Gaps = 2/217 (0%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 455 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 514
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 122
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 515 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 574
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
N K + R + + E ++ T L AR L E + K +E+ R ++ E+E
Sbjct: 575 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 633
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ ELE+ + + ++ ++ E+ ++
Sbjct: 634 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQ 670
Score = 50.4 bits (115), Expect = 7e-06
Identities = 51/217 (23%), Positives = 105/217 (48%), Gaps = 20/217 (9%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED----LIL 59
+K +M+ + KD+ E+ R + E++ ++ EL+ +L Q ED L +
Sbjct: 623 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL-QASEDAKLRLEV 681
Query: 60 NKNKLE-QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL--EKSEERSGTAQQKLLEA 116
N L+ Q +DL+ +++Q E + L R++ + E +L E++E A +K LE
Sbjct: 682 NMQALKGQFERDLQARDEQ---NEEKRRQLQRQLHEYETELEDERNERALAAAAKKKLEG 738
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
D + ++ R ++ +++ +L Q+K+ + EDA DE+ A ++
Sbjct: 739 DLK-DLELQADSAIKGR-EEAIKQLRKLQAQMKDFQRELEDARASRDEI---FATAKEN- 792
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E + KS +A + +L+E+L + K ++ +E+
Sbjct: 793 ---EKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 826
Score = 49.6 bits (113), Expect = 1e-05
Identities = 58/249 (23%), Positives = 106/249 (42%), Gaps = 15/249 (6%)
Query: 33 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 92
NL E++ E EL + ++ L K +LE+ ++E + ++ ++ A +K+
Sbjct: 4 NLLQEQLQAET-ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKM 62
Query: 93 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
Q DLE+ E A+QKL + +A+ K LE+ MD N+L + R
Sbjct: 63 AQQMLDLEEQLEEEEAARQKLQLEKVTAEAK---IKKLEDEILV----MDDQNNKLSKER 115
Query: 153 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
L E+ + +++ LA E++ + ++ ISELE LK S + LE +
Sbjct: 116 KLLEE---RISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 172
Query: 213 KANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLAD 272
K +F K ++LQ + RL+DE+ + K +
Sbjct: 173 KLEGDASDF---HEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR- 228
Query: 273 EMDSTFAEL 281
E++ ++L
Sbjct: 229 ELEGHISDL 237
Score = 46.8 bits (106), Expect = 9e-05
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 6/206 (2%)
Query: 15 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 74
K D A T E + R +K E + + ++ A + L KN+L+Q DL
Sbjct: 491 KKKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 549
Query: 75 EKQLTATEAEVAALNRKVQQI-EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
+ + RK Q+ E+ S + + + EA++ + + + LE
Sbjct: 550 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 609
Query: 134 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 193
+ EE + TN++ +A + ED D+V + + +E E +++ ++ EL
Sbjct: 610 LEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 665
Query: 194 EEELKVVGNSLKSLEVSEEKANQRVE 219
E+EL+ ++ LEV+ + + E
Sbjct: 666 EDELQASEDAKLRLEVNMQALKGQFE 691
Score = 46.4 bits (105), Expect = 1e-04
Identities = 36/178 (20%), Positives = 83/178 (46%), Gaps = 8/178 (4%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
++A++ K + + QQ + +K+ + LQ++L +DL+++ + Q
Sbjct: 501 VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL----DDLVVDLDNQRQL 556
Query: 68 NKDLEEKEKQLTATEAEVAALNRKV----QQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+LE+K+++ AE ++ K + E + + E ++ + + L EA ++ +E
Sbjct: 557 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEEL 616
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
R K+L+ + D + + E + + +E+ +L +EDEL+ +ED
Sbjct: 617 ERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQASED 674
Score = 46.4 bits (105), Expect = 1e-04
Identities = 58/286 (20%), Positives = 113/286 (39%), Gaps = 19/286 (6%)
Query: 16 DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKE 75
D + + + D RAE E LA+ E+ + K +LE+ NK L+ +
Sbjct: 568 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 627
Query: 76 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV------ 129
+ L +++ +V ++++ + LE E T ++L + Q++++ +V
Sbjct: 628 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQASEDAKLRLEVNMQALK 687
Query: 130 ------LENRAQQDEERMDQLTNQLKEARLLAEDADGK---SDEVSRKLAFVEDELEV-A 179
L+ R +Q+EE+ QL QL E ED + + +KL +LE+ A
Sbjct: 688 GQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERNERALAAAAKKKLEGDLKDLELQA 747
Query: 180 EDRVKSGDAKISE---LEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXX 236
+ +K + I + L+ ++K L+ S ++ +E
Sbjct: 748 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQ 807
Query: 237 XXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
+ K+ E + L +EL + +L DE A +A
Sbjct: 808 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 853
Score = 44.0 bits (99), Expect = 6e-04
Identities = 34/196 (17%), Positives = 86/196 (43%), Gaps = 1/196 (0%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E++ + A R + + KK+ ++E + + L+ + EKQ E+
Sbjct: 203 EEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 262
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV-LENRAQQDEERMDQL 144
AL +++ + +E +Q++ +++ DE R + ++ Q+ + +++L
Sbjct: 263 EALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 322
Query: 145 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL 204
T QL++ + + D + ++ A + EL V + + K +LE +++ + +
Sbjct: 323 TEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKC 382
Query: 205 KSLEVSEEKANQRVEE 220
E + + N +V +
Sbjct: 383 SDGERARAELNDKVHK 398
Score = 41.9 bits (94), Expect = 0.002
Identities = 40/259 (15%), Positives = 110/259 (42%), Gaps = 10/259 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+ ++ ++ A K E + + + + ++ D R +++ E +++ +++ +EE L +
Sbjct: 21 EEMRVRLAAKKQELEEILHEMEARLEEEED---RGQQLQAERKKMAQQMLDLEEQLEEEE 77
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ + E ++ E E+ ++ + ++ ++ + EER L E ++ A
Sbjct: 78 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 137
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
++ E+ + E R+ + +E L +G + + ++A ++ ++AE
Sbjct: 138 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ--AQIAEL 195
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXX 241
+++ +++ EEEL+ L + A +++ E
Sbjct: 196 KMQ-----LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNK 250
Query: 242 XXKTVKKLQKEVDRLEDEL 260
K + L +E++ L+ EL
Sbjct: 251 AEKQKRDLGEELEALKTEL 269
>X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin heavy
chain protein.
Length = 881
Score = 74.1 bits (174), Expect = 5e-13
Identities = 58/255 (22%), Positives = 116/255 (45%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ R+LQ++L + E +L + + A ++ E L E +
Sbjct: 484 QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 543
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+ + ++ + L K + + Q++L +A+ S DE K E +A+ E + QL
Sbjct: 544 SAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE 603
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
L A + AD + +E++ +LA +D + +A+I++LEEEL+ ++++
Sbjct: 604 DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA 663
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
+ KA Q+ E+ + K+L+ ++ +E G K +
Sbjct: 664 MSDRVRKATQQAEQLSNELATERSTAQKNESSRQQLERQNKELRSKLHEME---GAVKSK 720
Query: 267 YKSLADEMDSTFAEL 281
+KS +++ A+L
Sbjct: 721 FKSTIAALEAKIAQL 735
Score = 64.5 bits (150), Expect = 4e-10
Identities = 53/229 (23%), Positives = 103/229 (44%), Gaps = 11/229 (4%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQVEEDLILN 60
+AIK+ + KD + D + +RD K NE+ + L+ L Q++EDL
Sbjct: 551 EAIKQLRKLQAQMKDFQRELEDA--RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 608
Query: 61 KNKLEQANKDLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
+ +QA+ + EE ++L A + E L ++ Q+EE+LE+ + ++
Sbjct: 609 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 668
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK-SDEVSRKLAFV 172
+A Q A++ + + AQ++E QL Q KE R + +G + +A +
Sbjct: 669 RKATQQAEQLSNELATERSTAQKNESSRQQLERQNKELRSKLHEMEGAVKSKFKSTIAAL 728
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
E ++ E++V+ + + LK LK + + E + E++
Sbjct: 729 EAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY 777
Score = 55.6 bits (128), Expect = 2e-07
Identities = 45/222 (20%), Positives = 106/222 (47%), Gaps = 11/222 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E ++ +
Sbjct: 643 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNES---SRQQ 698
Query: 64 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 699 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 758
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 759 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 818
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
A + ++ +++ L+ +L+ GN S S +RV E
Sbjct: 819 ATESNEAMGREVNALKSKLR-RGNE-TSFVPSRRSGGRRVIE 858
Score = 54.8 bits (126), Expect = 3e-07
Identities = 56/270 (20%), Positives = 111/270 (41%), Gaps = 14/270 (5%)
Query: 9 QAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQAN 68
+A+KL KD A + Q +D ++ + + KL Q+EE+ +++L++
Sbjct: 211 KAIKLAKDVA-----SLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 265
Query: 69 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
+ + E+ ++ +++ +K+Q +E EE Q+++ Q +E
Sbjct: 266 EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD 325
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD- 187
LE + ++ +D L L R L + + K + + LA +E ++ D
Sbjct: 326 KLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA---EEKNISSKYADERDR 382
Query: 188 AKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVK 247
A+ E+E K + SL + E+A + EE K V
Sbjct: 383 AEAEAREKETKAL-----SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVH 437
Query: 248 KLQKEVDRLEDELGINKDRYKSLADEMDST 277
+L+K LE ++ K + + L DE+ +T
Sbjct: 438 ELEKSKRALETQMEEMKTQLEELEDELQAT 467
Score = 52.4 bits (120), Expect = 2e-06
Identities = 48/272 (17%), Positives = 125/272 (45%), Gaps = 28/272 (10%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQ----QARDANLRAEKVNEEVR-------ELQKKLAQVE 54
++++A+K E ++ +D T ++ + ++ + + ++EE R E+++K AQ
Sbjct: 55 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 114
Query: 55 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
E+L + ++A +L++ ++ L A++A R + Q ++++E ++K L
Sbjct: 115 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEH--------KKKKL 166
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
EAQ E C E + +++ +L N+++ + +A+GK+ ++++ +A +
Sbjct: 167 EAQ--VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 224
Query: 175 ELEVAEDRVK-------SGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXX 227
+L+ ++ ++ + K+ +LEEE + + L +++ + +
Sbjct: 225 QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 284
Query: 228 XXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE 259
+ K+ QKE++ L +
Sbjct: 285 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 316
Score = 52.0 bits (119), Expect = 2e-06
Identities = 65/304 (21%), Positives = 133/304 (43%), Gaps = 32/304 (10%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D K++ A +K D D E QA A E+ +++R+LQ ++ + +L +
Sbjct: 516 DERKQRALAAAAKKKLEGDLKDL-ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 574
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE-----DLEKSEERSGTA------- 109
++ +E EK+ + EA++ L + E DLEK E A
Sbjct: 575 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 634
Query: 110 ----QQKLLEA-----QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+++ LEA ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 635 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 694
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSG--------DAKISELEEELKVVGNSLKSLEVSEE 212
++ R+ + +L E VKS +AKI++LEE+++ ++ S +
Sbjct: 695 SRQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 754
Query: 213 KANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE-LGINKDRYKSLA 271
+ +++++E VK+L+++++ E+E IN +R K L
Sbjct: 755 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRK-LQ 813
Query: 272 DEMD 275
E+D
Sbjct: 814 RELD 817
Score = 50.8 bits (116), Expect = 5e-06
Identities = 37/217 (17%), Positives = 92/217 (42%), Gaps = 2/217 (0%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 250 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 309
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 122
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 310 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 369
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
N K + R + + E ++ T L AR L E + K +E+ R ++ E+E
Sbjct: 370 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 428
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ ELE+ + + ++ ++ E+ ++
Sbjct: 429 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQ 465
Score = 48.8 bits (111), Expect = 2e-05
Identities = 48/216 (22%), Positives = 103/216 (47%), Gaps = 18/216 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 60
+K +M+ + KD+ E+ R + E++ ++ EL+ +L E+ L +N
Sbjct: 418 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 477
Query: 61 KNKLE-QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL--EKSEERSGTAQQKLLEAQ 117
L+ Q +DL+ +++Q E + L R++ + E +L E+ + A +K LE
Sbjct: 478 MQALKGQFERDLQARDEQ---NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD 534
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
D + ++ R ++ +++ +L Q+K+ + EDA DE+ A ++
Sbjct: 535 LK-DLELQADSAIKGR-EEAIKQLRKLQAQMKDFQRELEDARASRDEI---FATAKEN-- 587
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E + KS +A + +L+E+L + K ++ +E+
Sbjct: 588 --EKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 621
Score = 48.4 bits (110), Expect = 3e-05
Identities = 39/188 (20%), Positives = 92/188 (48%), Gaps = 10/188 (5%)
Query: 36 AEKVN--EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 93
A+K N +++REL+ ++ ++EDL E+A ++ EK+K+ E E AL +++
Sbjct: 13 AQKNNALKKIRELEGHISDLQEDL-----DSERAARNKAEKQKRDLGEELE--ALKTELE 65
Query: 94 QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV-LENRAQQDEERMDQLTNQLKEAR 152
+ +E +Q++ +++ DE R + ++ Q+ + +++LT QL++ +
Sbjct: 66 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK 125
Query: 153 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
+ D + ++ A + EL V + + K +LE +++ + + E +
Sbjct: 126 RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 185
Query: 213 KANQRVEE 220
+ N +V +
Sbjct: 186 ELNDKVHK 193
Score = 47.6 bits (108), Expect = 5e-05
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 6/206 (2%)
Query: 15 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 74
K D A T E + R +K E + + ++ A + L KN+L+Q DL
Sbjct: 286 KKKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 344
Query: 75 EKQLTATEAEVAALNRKVQQI-EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
+ + RK Q+ E+ S + + + EA++ + + + LE
Sbjct: 345 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 404
Query: 134 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 193
+ EE + TN++ +A + ED D+V + + +E E +++ ++ EL
Sbjct: 405 LEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 460
Query: 194 EEELKVVGNSLKSLEVSEEKANQRVE 219
E+EL+ ++ LEV+ + + E
Sbjct: 461 EDELQATEDAKLRLEVNMQALKGQFE 486
Score = 46.0 bits (104), Expect = 2e-04
Identities = 36/178 (20%), Positives = 82/178 (46%), Gaps = 8/178 (4%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
++A++ K + + QQ + +K+ + LQ++L +DL+++ + Q
Sbjct: 296 VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL----DDLVVDLDNQRQL 351
Query: 68 NKDLEEKEKQLTATEAEVAALNRKV----QQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+LE+K+++ AE ++ K + E + + E ++ + + L EA ++ +E
Sbjct: 352 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEEL 411
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
R K+L+ + D + + E + + +E+ +L +EDEL+ ED
Sbjct: 412 ERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 469
Score = 45.2 bits (102), Expect = 3e-04
Identities = 63/287 (21%), Positives = 114/287 (39%), Gaps = 21/287 (7%)
Query: 16 DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKE 75
D + + + D RAE E LA+ E+ + K +LE+ NK L+ +
Sbjct: 363 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 422
Query: 76 KQLTATEAEVA-----------ALNRKVQQIEEDLEKSE-ERSGTAQQKL-LEAQQSADE 122
+ L +++ +V AL ++++++ LE+ E E T KL LE A
Sbjct: 423 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA-L 481
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK---SDEVSRKLAFVEDELEV- 178
+ + L+ R +Q+EE+ QL QL E ED + + +KL +LE+
Sbjct: 482 KGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQ 541
Query: 179 AEDRVKSGDAKISE---LEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXX 235
A+ +K + I + L+ ++K L+ S ++ +E
Sbjct: 542 ADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQL 601
Query: 236 XXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
+ K+ E + L +EL + +L DE A +A
Sbjct: 602 QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 648
>BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 74.1 bits (174), Expect = 5e-13
Identities = 58/255 (22%), Positives = 116/255 (45%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ R+LQ++L + E +L + + A ++ E L E +
Sbjct: 1575 QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1634
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+ + ++ + L K + + Q++L +A+ S DE K E +A+ E + QL
Sbjct: 1635 SAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE 1694
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
L A + AD + +E++ +LA +D + +A+I++LEEEL+ ++++
Sbjct: 1695 DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA 1754
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
+ KA Q+ E+ + K+L+ ++ +E G K +
Sbjct: 1755 MSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEME---GAVKSK 1811
Query: 267 YKSLADEMDSTFAEL 281
+KS +++ A+L
Sbjct: 1812 FKSTIAALEAKIAQL 1826
Score = 65.3 bits (152), Expect = 2e-10
Identities = 59/291 (20%), Positives = 124/291 (42%), Gaps = 11/291 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQVEEDLILN 60
+AIK+ + KD + D + +RD K NE+ + L+ L Q++EDL
Sbjct: 1642 EAIKQLRKLQAQMKDFQRELEDA--RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1699
Query: 61 KNKLEQANKDLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
+ +QA+ + EE ++L A + E L ++ Q+EE+LE+ + ++
Sbjct: 1700 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1759
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK-SDEVSRKLAFV 172
+A Q A++ + + AQ++E QL Q KE R + +G + +A +
Sbjct: 1760 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAAL 1819
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXX 232
E ++ E++V+ + + LK LK + + E + E++
Sbjct: 1820 EAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARV 1879
Query: 233 XXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAG 283
+ +++ +L+ EL + +++ E+++ ++L G
Sbjct: 1880 KQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRG 1930
Score = 59.3 bits (137), Expect = 2e-08
Identities = 64/284 (22%), Positives = 121/284 (42%), Gaps = 25/284 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL- 59
+ A +KKM L+ + ++ E++A L+ EKV E K+ ++E+++++
Sbjct: 941 LQAERKKMAQQMLDLEEQLE-----EEEAARQKLQLEKVTAEA-----KIKKLEDEILVM 990
Query: 60 --NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
NKL + K LEE+ LT AE K + + + K E + +L + +
Sbjct: 991 DDQNNKLSKERKLLEERISDLTTNLAEE---EEKAKNLTKLKNKHESMISELEVRLKKEE 1047
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAEDADGKSDEVSRKLAFVEDEL 176
+S E ++ + LE A E++ L Q+ E ++ LA+ K +E+ LA ++DE+
Sbjct: 1048 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK----KEEELQAALARLDDEI 1103
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXX 236
+ +K KI ELE + + L S + KA ++ +
Sbjct: 1104 AQKNNALK----KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1159
Query: 237 XXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
+ K ++EV L+ L +++ EM A+
Sbjct: 1160 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQ 1203
Score = 54.8 bits (126), Expect = 3e-07
Identities = 56/270 (20%), Positives = 111/270 (41%), Gaps = 14/270 (5%)
Query: 9 QAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQAN 68
+A+KL KD A + Q +D ++ + + KL Q+EE+ +++L++
Sbjct: 1302 KAIKLAKDVA-----SLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1356
Query: 69 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
+ + E+ ++ +++ +K+Q +E EE Q+++ Q +E
Sbjct: 1357 EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD 1416
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD- 187
LE + ++ +D L L R L + + K + + LA +E ++ D
Sbjct: 1417 KLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA---EEKNISSKYADERDR 1473
Query: 188 AKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVK 247
A+ E+E K + SL + E+A + EE K V
Sbjct: 1474 AEAEAREKETKAL-----SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVH 1528
Query: 248 KLQKEVDRLEDELGINKDRYKSLADEMDST 277
+L+K LE ++ K + + L DE+ +T
Sbjct: 1529 ELEKSKRALETQMEEMKTQLEELEDELQAT 1558
Score = 53.6 bits (123), Expect = 8e-07
Identities = 66/287 (22%), Positives = 122/287 (42%), Gaps = 24/287 (8%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-------AQVEEDL 57
+++MQA + E ++ E + ++ + ++ EE LQ++L A+ EE
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 58 ILNKNKLEQANKDLEEKEKQLTATE---AEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
+ K ++ + L E E +L E ++ A +K+ Q DLE+ E A+QKL
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
+ +A+ K LE+ MD N+L + R L E+ + +++ LA E+
Sbjct: 971 LEKVTAEAK---IKKLEDEILV----MDDQNNKLSKERKLLEE---RISDLTTNLAEEEE 1020
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXX 234
+ + ++ ISELE LK S + LE + K +F
Sbjct: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF---HEQIADLQAQ 1077
Query: 235 XXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K ++LQ + RL+DE+ + K + E++ ++L
Sbjct: 1078 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR-ELEGHISDL 1123
Score = 52.4 bits (120), Expect = 2e-06
Identities = 48/272 (17%), Positives = 125/272 (45%), Gaps = 28/272 (10%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQ----QARDANLRAEKVNEEVR-------ELQKKLAQVE 54
++++A+K E ++ +D T ++ + ++ + + ++EE R E+++K AQ
Sbjct: 1146 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1205
Query: 55 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
E+L + ++A +L++ ++ L A++A R + Q ++++E ++K L
Sbjct: 1206 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEH--------KKKKL 1257
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
EAQ E C E + +++ +L N+++ + +A+GK+ ++++ +A +
Sbjct: 1258 EAQ--VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1315
Query: 175 ELEVAEDRVK-------SGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXX 227
+L+ ++ ++ + K+ +LEEE + + L +++ + +
Sbjct: 1316 QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 1375
Query: 228 XXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE 259
+ K+ QKE++ L +
Sbjct: 1376 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1407
Score = 51.6 bits (118), Expect = 3e-06
Identities = 65/304 (21%), Positives = 133/304 (43%), Gaps = 32/304 (10%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D K++ A +K D D E QA A E+ +++R+LQ ++ + +L +
Sbjct: 1607 DERKQRALAAAAKKKLEGDLKDL-ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1665
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE-----DLEKSEERSGTA------- 109
++ +E EK+ + EA++ L + E DLEK E A
Sbjct: 1666 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1725
Query: 110 ----QQKLLEA-----QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+++ LEA ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 1726 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1785
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSG--------DAKISELEEELKVVGNSLKSLEVSEE 212
++ R+ + +L E VKS +AKI++LEE+++ ++ S +
Sbjct: 1786 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1845
Query: 213 KANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE-LGINKDRYKSLA 271
+ +++++E VK+L+++++ E+E IN +R K L
Sbjct: 1846 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRK-LQ 1904
Query: 272 DEMD 275
E+D
Sbjct: 1905 RELD 1908
Score = 50.8 bits (116), Expect = 5e-06
Identities = 37/217 (17%), Positives = 92/217 (42%), Gaps = 2/217 (0%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 1341 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1400
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 122
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 1401 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1460
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
N K + R + + E ++ T L AR L E + K +E+ R ++ E+E
Sbjct: 1461 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 1519
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ ELE+ + + ++ ++ E+ ++
Sbjct: 1520 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQ 1556
Score = 48.8 bits (111), Expect = 2e-05
Identities = 48/216 (22%), Positives = 103/216 (47%), Gaps = 18/216 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 60
+K +M+ + KD+ E+ R + E++ ++ EL+ +L E+ L +N
Sbjct: 1509 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1568
Query: 61 KNKLE-QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL--EKSEERSGTAQQKLLEAQ 117
L+ Q +DL+ +++Q E + L R++ + E +L E+ + A +K LE
Sbjct: 1569 MQALKGQFERDLQARDEQ---NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD 1625
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
D + ++ R ++ +++ +L Q+K+ + EDA DE+ A ++
Sbjct: 1626 LK-DLELQADSAIKGR-EEAIKQLRKLQAQMKDFQRELEDARASRDEI---FATAKEN-- 1678
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E + KS +A + +L+E+L + K ++ +E+
Sbjct: 1679 --EKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 1712
Score = 48.4 bits (110), Expect = 3e-05
Identities = 43/240 (17%), Positives = 102/240 (42%), Gaps = 4/240 (1%)
Query: 42 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 101
+V ++++ E++L K + ++A +L+E E++ + E L ++Q E +
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 102 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
+EE K E ++ E + E+R QQ + ++ Q+ + E+ +
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 965
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
++ + E +++ ED + D + ++L +E K++ + L + + ++ +
Sbjct: 966 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K+ ++L+K +LE G D ++ +AD + + AEL
Sbjct: 1026 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE---GDASDFHEQIAD-LQAQIAEL 1081
Score = 47.6 bits (108), Expect = 5e-05
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 6/206 (2%)
Query: 15 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 74
K D A T E + R +K E + + ++ A + L KN+L+Q DL
Sbjct: 1377 KKKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1435
Query: 75 EKQLTATEAEVAALNRKVQQI-EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
+ + RK Q+ E+ S + + + EA++ + + + LE
Sbjct: 1436 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1495
Query: 134 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 193
+ EE + TN++ +A + ED D+V + + +E E +++ ++ EL
Sbjct: 1496 LEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 1551
Query: 194 EEELKVVGNSLKSLEVSEEKANQRVE 219
E+EL+ ++ LEV+ + + E
Sbjct: 1552 EDELQATEDAKLRLEVNMQALKGQFE 1577
Score = 46.0 bits (104), Expect = 2e-04
Identities = 36/178 (20%), Positives = 82/178 (46%), Gaps = 8/178 (4%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
++A++ K + + QQ + +K+ + LQ++L +DL+++ + Q
Sbjct: 1387 VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL----DDLVVDLDNQRQL 1442
Query: 68 NKDLEEKEKQLTATEAEVAALNRKV----QQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+LE+K+++ AE ++ K + E + + E ++ + + L EA ++ +E
Sbjct: 1443 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEEL 1502
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
R K+L+ + D + + E + + +E+ +L +EDEL+ ED
Sbjct: 1503 ERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1560
Score = 45.2 bits (102), Expect = 3e-04
Identities = 63/287 (21%), Positives = 114/287 (39%), Gaps = 21/287 (7%)
Query: 16 DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKE 75
D + + + D RAE E LA+ E+ + K +LE+ NK L+ +
Sbjct: 1454 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1513
Query: 76 KQLTATEAEVA-----------ALNRKVQQIEEDLEKSE-ERSGTAQQKL-LEAQQSADE 122
+ L +++ +V AL ++++++ LE+ E E T KL LE A
Sbjct: 1514 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA-L 1572
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK---SDEVSRKLAFVEDELEV- 178
+ + L+ R +Q+EE+ QL QL E ED + + +KL +LE+
Sbjct: 1573 KGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQ 1632
Query: 179 AEDRVKSGDAKISE---LEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXX 235
A+ +K + I + L+ ++K L+ S ++ +E
Sbjct: 1633 ADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQL 1692
Query: 236 XXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
+ K+ E + L +EL + +L DE A +A
Sbjct: 1693 QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1739
Score = 44.0 bits (99), Expect = 6e-04
Identities = 34/196 (17%), Positives = 86/196 (43%), Gaps = 1/196 (0%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E++ + A R + + KK+ ++E + + L+ + EKQ E+
Sbjct: 1089 EEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1148
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV-LENRAQQDEERMDQL 144
AL +++ + +E +Q++ +++ DE R + ++ Q+ + +++L
Sbjct: 1149 EALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1208
Query: 145 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL 204
T QL++ + + D + ++ A + EL V + + K +LE +++ + +
Sbjct: 1209 TEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKC 1268
Query: 205 KSLEVSEEKANQRVEE 220
E + + N +V +
Sbjct: 1269 SDGERARAELNDKVHK 1284
Score = 41.9 bits (94), Expect = 0.002
Identities = 40/259 (15%), Positives = 110/259 (42%), Gaps = 10/259 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+ ++ ++ A K E + + + + ++ D R +++ E +++ +++ +EE L +
Sbjct: 907 EEMRVRLAAKKQELEEILHEMEARLEEEED---RGQQLQAERKKMAQQMLDLEEQLEEEE 963
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ + E ++ E E+ ++ + ++ ++ + EER L E ++ A
Sbjct: 964 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1023
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
++ E+ + E R+ + +E L +G + + ++A ++ ++AE
Sbjct: 1024 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ--AQIAEL 1081
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXX 241
+++ +++ EEEL+ L + A +++ E
Sbjct: 1082 KMQ-----LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNK 1136
Query: 242 XXKTVKKLQKEVDRLEDEL 260
K + L +E++ L+ EL
Sbjct: 1137 AEKQKRDLGEELEALKTEL 1155
>BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 74.1 bits (174), Expect = 5e-13
Identities = 58/255 (22%), Positives = 116/255 (45%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ R+LQ++L + E +L + + A ++ E L E +
Sbjct: 1575 QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1634
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+ + ++ + L K + + Q++L +A+ S DE K E +A+ E + QL
Sbjct: 1635 SAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE 1694
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
L A + AD + +E++ +LA +D + +A+I++LEEEL+ ++++
Sbjct: 1695 DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA 1754
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
+ KA Q+ E+ + K+L+ ++ +E G K +
Sbjct: 1755 MSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEME---GAVKSK 1811
Query: 267 YKSLADEMDSTFAEL 281
+KS +++ A+L
Sbjct: 1812 FKSTIAALEAKIAQL 1826
Score = 65.3 bits (152), Expect = 2e-10
Identities = 59/291 (20%), Positives = 124/291 (42%), Gaps = 11/291 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQVEEDLILN 60
+AIK+ + KD + D + +RD K NE+ + L+ L Q++EDL
Sbjct: 1642 EAIKQLRKLQAQMKDFQRELEDA--RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1699
Query: 61 KNKLEQANKDLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
+ +QA+ + EE ++L A + E L ++ Q+EE+LE+ + ++
Sbjct: 1700 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1759
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK-SDEVSRKLAFV 172
+A Q A++ + + AQ++E QL Q KE R + +G + +A +
Sbjct: 1760 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAAL 1819
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXX 232
E ++ E++V+ + + LK LK + + E + E++
Sbjct: 1820 EAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARV 1879
Query: 233 XXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAG 283
+ +++ +L+ EL + +++ E+++ ++L G
Sbjct: 1880 KQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRG 1930
Score = 59.3 bits (137), Expect = 2e-08
Identities = 64/284 (22%), Positives = 121/284 (42%), Gaps = 25/284 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL- 59
+ A +KKM L+ + ++ E++A L+ EKV E K+ ++E+++++
Sbjct: 941 LQAERKKMAQQMLDLEEQLE-----EEEAARQKLQLEKVTAEA-----KIKKLEDEILVM 990
Query: 60 --NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
NKL + K LEE+ LT AE K + + + K E + +L + +
Sbjct: 991 DDQNNKLSKERKLLEERISDLTTNLAEE---EEKAKNLTKLKNKHESMISELEVRLKKEE 1047
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAEDADGKSDEVSRKLAFVEDEL 176
+S E ++ + LE A E++ L Q+ E ++ LA+ K +E+ LA ++DE+
Sbjct: 1048 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK----KEEELQAALARLDDEI 1103
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXX 236
+ +K KI ELE + + L S + KA ++ +
Sbjct: 1104 AQKNNALK----KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1159
Query: 237 XXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
+ K ++EV L+ L +++ EM A+
Sbjct: 1160 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQ 1203
Score = 54.8 bits (126), Expect = 3e-07
Identities = 56/270 (20%), Positives = 111/270 (41%), Gaps = 14/270 (5%)
Query: 9 QAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQAN 68
+A+KL KD A + Q +D ++ + + KL Q+EE+ +++L++
Sbjct: 1302 KAIKLAKDVA-----SLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1356
Query: 69 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
+ + E+ ++ +++ +K+Q +E EE Q+++ Q +E
Sbjct: 1357 EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD 1416
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD- 187
LE + ++ +D L L R L + + K + + LA +E ++ D
Sbjct: 1417 KLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA---EEKNISSKYADERDR 1473
Query: 188 AKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVK 247
A+ E+E K + SL + E+A + EE K V
Sbjct: 1474 AEAEAREKETKAL-----SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVH 1528
Query: 248 KLQKEVDRLEDELGINKDRYKSLADEMDST 277
+L+K LE ++ K + + L DE+ +T
Sbjct: 1529 ELEKSKRALETQMEEMKTQLEELEDELQAT 1558
Score = 53.6 bits (123), Expect = 8e-07
Identities = 66/287 (22%), Positives = 122/287 (42%), Gaps = 24/287 (8%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-------AQVEEDL 57
+++MQA + E ++ E + ++ + ++ EE LQ++L A+ EE
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 58 ILNKNKLEQANKDLEEKEKQLTATE---AEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
+ K ++ + L E E +L E ++ A +K+ Q DLE+ E A+QKL
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
+ +A+ K LE+ MD N+L + R L E+ + +++ LA E+
Sbjct: 971 LEKVTAEAK---IKKLEDEILV----MDDQNNKLSKERKLLEE---RISDLTTNLAEEEE 1020
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXX 234
+ + ++ ISELE LK S + LE + K +F
Sbjct: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF---HEQIADLQAQ 1077
Query: 235 XXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K ++LQ + RL+DE+ + K + E++ ++L
Sbjct: 1078 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR-ELEGHISDL 1123
Score = 52.4 bits (120), Expect = 2e-06
Identities = 48/272 (17%), Positives = 125/272 (45%), Gaps = 28/272 (10%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQ----QARDANLRAEKVNEEVR-------ELQKKLAQVE 54
++++A+K E ++ +D T ++ + ++ + + ++EE R E+++K AQ
Sbjct: 1146 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1205
Query: 55 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
E+L + ++A +L++ ++ L A++A R + Q ++++E ++K L
Sbjct: 1206 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEH--------KKKKL 1257
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
EAQ E C E + +++ +L N+++ + +A+GK+ ++++ +A +
Sbjct: 1258 EAQ--VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1315
Query: 175 ELEVAEDRVK-------SGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXX 227
+L+ ++ ++ + K+ +LEEE + + L +++ + +
Sbjct: 1316 QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 1375
Query: 228 XXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE 259
+ K+ QKE++ L +
Sbjct: 1376 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1407
Score = 51.6 bits (118), Expect = 3e-06
Identities = 65/304 (21%), Positives = 133/304 (43%), Gaps = 32/304 (10%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D K++ A +K D D E QA A E+ +++R+LQ ++ + +L +
Sbjct: 1607 DERKQRALAAAAKKKLEGDLKDL-ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1665
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE-----DLEKSEERSGTA------- 109
++ +E EK+ + EA++ L + E DLEK E A
Sbjct: 1666 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1725
Query: 110 ----QQKLLEA-----QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+++ LEA ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 1726 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1785
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSG--------DAKISELEEELKVVGNSLKSLEVSEE 212
++ R+ + +L E VKS +AKI++LEE+++ ++ S +
Sbjct: 1786 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1845
Query: 213 KANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE-LGINKDRYKSLA 271
+ +++++E VK+L+++++ E+E IN +R K L
Sbjct: 1846 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRK-LQ 1904
Query: 272 DEMD 275
E+D
Sbjct: 1905 RELD 1908
Score = 50.8 bits (116), Expect = 5e-06
Identities = 37/217 (17%), Positives = 92/217 (42%), Gaps = 2/217 (0%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 1341 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1400
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 122
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 1401 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1460
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
N K + R + + E ++ T L AR L E + K +E+ R ++ E+E
Sbjct: 1461 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 1519
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ ELE+ + + ++ ++ E+ ++
Sbjct: 1520 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQ 1556
Score = 48.8 bits (111), Expect = 2e-05
Identities = 48/216 (22%), Positives = 103/216 (47%), Gaps = 18/216 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 60
+K +M+ + KD+ E+ R + E++ ++ EL+ +L E+ L +N
Sbjct: 1509 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1568
Query: 61 KNKLE-QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL--EKSEERSGTAQQKLLEAQ 117
L+ Q +DL+ +++Q E + L R++ + E +L E+ + A +K LE
Sbjct: 1569 MQALKGQFERDLQARDEQ---NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD 1625
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
D + ++ R ++ +++ +L Q+K+ + EDA DE+ A ++
Sbjct: 1626 LK-DLELQADSAIKGR-EEAIKQLRKLQAQMKDFQRELEDARASRDEI---FATAKEN-- 1678
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E + KS +A + +L+E+L + K ++ +E+
Sbjct: 1679 --EKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 1712
Score = 48.4 bits (110), Expect = 3e-05
Identities = 43/240 (17%), Positives = 102/240 (42%), Gaps = 4/240 (1%)
Query: 42 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 101
+V ++++ E++L K + ++A +L+E E++ + E L ++Q E +
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 102 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
+EE K E ++ E + E+R QQ + ++ Q+ + E+ +
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 965
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
++ + E +++ ED + D + ++L +E K++ + L + + ++ +
Sbjct: 966 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K+ ++L+K +LE G D ++ +AD + + AEL
Sbjct: 1026 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE---GDASDFHEQIAD-LQAQIAEL 1081
Score = 47.6 bits (108), Expect = 5e-05
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 6/206 (2%)
Query: 15 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 74
K D A T E + R +K E + + ++ A + L KN+L+Q DL
Sbjct: 1377 KKKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1435
Query: 75 EKQLTATEAEVAALNRKVQQI-EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
+ + RK Q+ E+ S + + + EA++ + + + LE
Sbjct: 1436 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1495
Query: 134 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 193
+ EE + TN++ +A + ED D+V + + +E E +++ ++ EL
Sbjct: 1496 LEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 1551
Query: 194 EEELKVVGNSLKSLEVSEEKANQRVE 219
E+EL+ ++ LEV+ + + E
Sbjct: 1552 EDELQATEDAKLRLEVNMQALKGQFE 1577
Score = 46.0 bits (104), Expect = 2e-04
Identities = 36/178 (20%), Positives = 82/178 (46%), Gaps = 8/178 (4%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
++A++ K + + QQ + +K+ + LQ++L +DL+++ + Q
Sbjct: 1387 VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL----DDLVVDLDNQRQL 1442
Query: 68 NKDLEEKEKQLTATEAEVAALNRKV----QQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+LE+K+++ AE ++ K + E + + E ++ + + L EA ++ +E
Sbjct: 1443 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEEL 1502
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
R K+L+ + D + + E + + +E+ +L +EDEL+ ED
Sbjct: 1503 ERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1560
Score = 45.2 bits (102), Expect = 3e-04
Identities = 63/287 (21%), Positives = 114/287 (39%), Gaps = 21/287 (7%)
Query: 16 DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKE 75
D + + + D RAE E LA+ E+ + K +LE+ NK L+ +
Sbjct: 1454 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1513
Query: 76 KQLTATEAEVA-----------ALNRKVQQIEEDLEKSE-ERSGTAQQKL-LEAQQSADE 122
+ L +++ +V AL ++++++ LE+ E E T KL LE A
Sbjct: 1514 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA-L 1572
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK---SDEVSRKLAFVEDELEV- 178
+ + L+ R +Q+EE+ QL QL E ED + + +KL +LE+
Sbjct: 1573 KGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQ 1632
Query: 179 AEDRVKSGDAKISE---LEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXX 235
A+ +K + I + L+ ++K L+ S ++ +E
Sbjct: 1633 ADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQL 1692
Query: 236 XXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
+ K+ E + L +EL + +L DE A +A
Sbjct: 1693 QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1739
Score = 44.0 bits (99), Expect = 6e-04
Identities = 34/196 (17%), Positives = 86/196 (43%), Gaps = 1/196 (0%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E++ + A R + + KK+ ++E + + L+ + EKQ E+
Sbjct: 1089 EEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1148
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV-LENRAQQDEERMDQL 144
AL +++ + +E +Q++ +++ DE R + ++ Q+ + +++L
Sbjct: 1149 EALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1208
Query: 145 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL 204
T QL++ + + D + ++ A + EL V + + K +LE +++ + +
Sbjct: 1209 TEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKC 1268
Query: 205 KSLEVSEEKANQRVEE 220
E + + N +V +
Sbjct: 1269 SDGERARAELNDKVHK 1284
Score = 41.9 bits (94), Expect = 0.002
Identities = 40/259 (15%), Positives = 110/259 (42%), Gaps = 10/259 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+ ++ ++ A K E + + + + ++ D R +++ E +++ +++ +EE L +
Sbjct: 907 EEMRVRLAAKKQELEEILHEMEARLEEEED---RGQQLQAERKKMAQQMLDLEEQLEEEE 963
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ + E ++ E E+ ++ + ++ ++ + EER L E ++ A
Sbjct: 964 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1023
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
++ E+ + E R+ + +E L +G + + ++A ++ ++AE
Sbjct: 1024 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ--AQIAEL 1081
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXX 241
+++ +++ EEEL+ L + A +++ E
Sbjct: 1082 KMQ-----LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNK 1136
Query: 242 XXKTVKKLQKEVDRLEDEL 260
K + L +E++ L+ EL
Sbjct: 1137 AEKQKRDLGEELEALKTEL 1155
>BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein.
Length = 498
Score = 74.1 bits (174), Expect = 5e-13
Identities = 58/255 (22%), Positives = 116/255 (45%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ R+LQ++L + E +L + + A ++ E L E +
Sbjct: 101 QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 160
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+ + ++ + L K + + Q++L +A+ S DE K E +A+ E + QL
Sbjct: 161 SAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE 220
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
L A + AD + +E++ +LA +D + +A+I++LEEEL+ ++++
Sbjct: 221 DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA 280
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
+ KA Q+ E+ + K+L+ ++ +E G K +
Sbjct: 281 MSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEME---GAVKSK 337
Query: 267 YKSLADEMDSTFAEL 281
+KS +++ A+L
Sbjct: 338 FKSTIAALEAKIAQL 352
Score = 64.5 bits (150), Expect = 4e-10
Identities = 53/229 (23%), Positives = 103/229 (44%), Gaps = 11/229 (4%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQVEEDLILN 60
+AIK+ + KD + D + +RD K NE+ + L+ L Q++EDL
Sbjct: 168 EAIKQLRKLQAQMKDFQRELEDA--RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 225
Query: 61 KNKLEQANKDLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
+ +QA+ + EE ++L A + E L ++ Q+EE+LE+ + ++
Sbjct: 226 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 285
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK-SDEVSRKLAFV 172
+A Q A++ + + AQ++E QL Q KE R + +G + +A +
Sbjct: 286 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAAL 345
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
E ++ E++V+ + + LK LK + + E + E++
Sbjct: 346 EAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY 394
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/222 (20%), Positives = 105/222 (47%), Gaps = 11/222 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 260 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 315
Query: 64 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 316 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 375
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 376 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 435
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
A + ++ +++ L+ +L+ GN S S +RV E
Sbjct: 436 ATESNEAMGREVNALKSKLR-RGNE-TSFVPSRRSGGRRVIE 475
Score = 51.6 bits (118), Expect = 3e-06
Identities = 56/289 (19%), Positives = 120/289 (41%), Gaps = 14/289 (4%)
Query: 3 AIKKKMQAMK-LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
A+++ ++A + LE+ N M KA+ D + V + V EL+K +E + K
Sbjct: 17 ALEEALEAKEELERTNKMLKAEM-----EDLVSSKDDVGKNVHELEKSKRALETQMEEMK 71
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ-IEEDLEKSEERSGTAQQKLLEAQQSA 120
+LE+ +L+ E E + AL + ++ ++ E++EE+ Q++L E +
Sbjct: 72 TQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 131
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE--- 177
++ + + ++ E + L Q A E+A + ++ ++ + ELE
Sbjct: 132 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 191
Query: 178 VAEDRV----KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXX 233
+ D + K + K LE +L + L + E + ++A+ EE
Sbjct: 192 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 251
Query: 234 XXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
+ +L++E++ + + DR + + + ELA
Sbjct: 252 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELA 300
Score = 51.6 bits (118), Expect = 3e-06
Identities = 65/304 (21%), Positives = 133/304 (43%), Gaps = 32/304 (10%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D K++ A +K D D E QA A E+ +++R+LQ ++ + +L +
Sbjct: 133 DERKQRALAAAAKKKLEGDLKDL-ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 191
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE-----DLEKSEERSGTA------- 109
++ +E EK+ + EA++ L + E DLEK E A
Sbjct: 192 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 251
Query: 110 ----QQKLLEA-----QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+++ LEA ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 252 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 311
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSG--------DAKISELEEELKVVGNSLKSLEVSEE 212
++ R+ + +L E VKS +AKI++LEE+++ ++ S +
Sbjct: 312 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 371
Query: 213 KANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE-LGINKDRYKSLA 271
+ +++++E VK+L+++++ E+E IN +R K L
Sbjct: 372 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRK-LQ 430
Query: 272 DEMD 275
E+D
Sbjct: 431 RELD 434
Score = 35.5 bits (78), Expect = 0.21
Identities = 24/105 (22%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
EA++ + + + LE + EE + TN++ +A + ED D+V + + +E
Sbjct: 3 EAREKETKALSLARALEEALEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEK 58
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
E +++ ++ ELE+EL+ ++ LEV+ + + E
Sbjct: 59 SKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFE 103
Score = 31.5 bits (68), Expect = 3.5
Identities = 19/86 (22%), Positives = 40/86 (46%)
Query: 96 EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
E + + E ++ + + L EA ++ +E R K+L+ + D + + E
Sbjct: 1 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 60
Query: 156 EDADGKSDEVSRKLAFVEDELEVAED 181
+ + +E+ +L +EDEL+ ED
Sbjct: 61 RALETQMEEMKTQLEELEDELQATED 86
>AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 1945
Score = 74.1 bits (174), Expect = 5e-13
Identities = 58/255 (22%), Positives = 116/255 (45%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ R+LQ++L + E +L + + A ++ E L E +
Sbjct: 1582 QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1641
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+ + ++ + L K + + Q++L +A+ S DE K E +A+ E + QL
Sbjct: 1642 SAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE 1701
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
L A + AD + +E++ +LA +D + +A+I++LEEEL+ ++++
Sbjct: 1702 DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA 1761
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
+ KA Q+ E+ + K+L+ ++ +E G K +
Sbjct: 1762 MSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEME---GAVKSK 1818
Query: 267 YKSLADEMDSTFAEL 281
+KS +++ A+L
Sbjct: 1819 FKSTIAALEAKIAQL 1833
Score = 65.3 bits (152), Expect = 2e-10
Identities = 59/291 (20%), Positives = 124/291 (42%), Gaps = 11/291 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQVEEDLILN 60
+AIK+ + KD + D + +RD K NE+ + L+ L Q++EDL
Sbjct: 1649 EAIKQLRKLQAQMKDFQRELEDA--RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1706
Query: 61 KNKLEQANKDLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
+ +QA+ + EE ++L A + E L ++ Q+EE+LE+ + ++
Sbjct: 1707 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1766
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK-SDEVSRKLAFV 172
+A Q A++ + + AQ++E QL Q KE R + +G + +A +
Sbjct: 1767 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAAL 1826
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXX 232
E ++ E++V+ + + LK LK + + E + E++
Sbjct: 1827 EAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARV 1886
Query: 233 XXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAG 283
+ +++ +L+ EL + +++ E+++ ++L G
Sbjct: 1887 KQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRG 1937
Score = 59.3 bits (137), Expect = 2e-08
Identities = 64/284 (22%), Positives = 121/284 (42%), Gaps = 25/284 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL- 59
+ A +KKM L+ + ++ E++A L+ EKV E K+ ++E+++++
Sbjct: 948 LQAERKKMAQQMLDLEEQLE-----EEEAARQKLQLEKVTAEA-----KIKKLEDEILVM 997
Query: 60 --NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
NKL + K LEE+ LT AE K + + + K E + +L + +
Sbjct: 998 DDQNNKLSKERKLLEERISDLTTNLAEE---EEKAKNLTKLKNKHESMISELEVRLKKEE 1054
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAEDADGKSDEVSRKLAFVEDEL 176
+S E ++ + LE A E++ L Q+ E ++ LA+ K +E+ LA ++DE+
Sbjct: 1055 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK----KEEELQAALARLDDEI 1110
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXX 236
+ +K KI ELE + + L S + KA ++ +
Sbjct: 1111 AQKNNALK----KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1166
Query: 237 XXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
+ K ++EV L+ L +++ EM A+
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQ 1210
Score = 54.8 bits (126), Expect = 3e-07
Identities = 56/270 (20%), Positives = 111/270 (41%), Gaps = 14/270 (5%)
Query: 9 QAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQAN 68
+A+KL KD A + Q +D ++ + + KL Q+EE+ +++L++
Sbjct: 1309 KAIKLAKDVA-----SLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1363
Query: 69 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
+ + E+ ++ +++ +K+Q +E EE Q+++ Q +E
Sbjct: 1364 EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD 1423
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD- 187
LE + ++ +D L L R L + + K + + LA +E ++ D
Sbjct: 1424 KLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA---EEKNISSKYADERDR 1480
Query: 188 AKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVK 247
A+ E+E K + SL + E+A + EE K V
Sbjct: 1481 AEAEAREKETKAL-----SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVH 1535
Query: 248 KLQKEVDRLEDELGINKDRYKSLADEMDST 277
+L+K LE ++ K + + L DE+ +T
Sbjct: 1536 ELEKSKRALETQMEEMKTQLEELEDELQAT 1565
Score = 53.6 bits (123), Expect = 8e-07
Identities = 66/287 (22%), Positives = 122/287 (42%), Gaps = 24/287 (8%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-------AQVEEDL 57
+++MQA + E ++ E + ++ + ++ EE LQ++L A+ EE
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 58 ILNKNKLEQANKDLEEKEKQLTATE---AEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
+ K ++ + L E E +L E ++ A +K+ Q DLE+ E A+QKL
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 977
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
+ +A+ K LE+ MD N+L + R L E+ + +++ LA E+
Sbjct: 978 LEKVTAEAK---IKKLEDEILV----MDDQNNKLSKERKLLEE---RISDLTTNLAEEEE 1027
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXX 234
+ + ++ ISELE LK S + LE + K +F
Sbjct: 1028 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF---HEQIADLQAQ 1084
Query: 235 XXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K ++LQ + RL+DE+ + K + E++ ++L
Sbjct: 1085 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR-ELEGHISDL 1130
Score = 52.4 bits (120), Expect = 2e-06
Identities = 48/272 (17%), Positives = 125/272 (45%), Gaps = 28/272 (10%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQ----QARDANLRAEKVNEEVR-------ELQKKLAQVE 54
++++A+K E ++ +D T ++ + ++ + + ++EE R E+++K AQ
Sbjct: 1153 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1212
Query: 55 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
E+L + ++A +L++ ++ L A++A R + Q ++++E ++K L
Sbjct: 1213 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEH--------KKKKL 1264
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
EAQ E C E + +++ +L N+++ + +A+GK+ ++++ +A +
Sbjct: 1265 EAQ--VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1322
Query: 175 ELEVAEDRVK-------SGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXX 227
+L+ ++ ++ + K+ +LEEE + + L +++ + +
Sbjct: 1323 QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 1382
Query: 228 XXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE 259
+ K+ QKE++ L +
Sbjct: 1383 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1414
Score = 51.6 bits (118), Expect = 3e-06
Identities = 65/304 (21%), Positives = 133/304 (43%), Gaps = 32/304 (10%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D K++ A +K D D E QA A E+ +++R+LQ ++ + +L +
Sbjct: 1614 DERKQRALAAAAKKKLEGDLKDL-ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1672
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE-----DLEKSEERSGTA------- 109
++ +E EK+ + EA++ L + E DLEK E A
Sbjct: 1673 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1732
Query: 110 ----QQKLLEA-----QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+++ LEA ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 1733 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1792
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSG--------DAKISELEEELKVVGNSLKSLEVSEE 212
++ R+ + +L E VKS +AKI++LEE+++ ++ S +
Sbjct: 1793 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1852
Query: 213 KANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE-LGINKDRYKSLA 271
+ +++++E VK+L+++++ E+E IN +R K L
Sbjct: 1853 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRK-LQ 1911
Query: 272 DEMD 275
E+D
Sbjct: 1912 RELD 1915
Score = 50.8 bits (116), Expect = 5e-06
Identities = 37/217 (17%), Positives = 92/217 (42%), Gaps = 2/217 (0%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 1348 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1407
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 122
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 1408 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1467
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
N K + R + + E ++ T L AR L E + K +E+ R ++ E+E
Sbjct: 1468 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 1526
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ ELE+ + + ++ ++ E+ ++
Sbjct: 1527 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQ 1563
Score = 48.8 bits (111), Expect = 2e-05
Identities = 48/216 (22%), Positives = 103/216 (47%), Gaps = 18/216 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 60
+K +M+ + KD+ E+ R + E++ ++ EL+ +L E+ L +N
Sbjct: 1516 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1575
Query: 61 KNKLE-QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL--EKSEERSGTAQQKLLEAQ 117
L+ Q +DL+ +++Q E + L R++ + E +L E+ + A +K LE
Sbjct: 1576 MQALKGQFERDLQARDEQ---NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD 1632
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
D + ++ R ++ +++ +L Q+K+ + EDA DE+ A ++
Sbjct: 1633 LK-DLELQADSAIKGR-EEAIKQLRKLQAQMKDFQRELEDARASRDEI---FATAKEN-- 1685
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E + KS +A + +L+E+L + K ++ +E+
Sbjct: 1686 --EKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 1719
Score = 48.4 bits (110), Expect = 3e-05
Identities = 43/240 (17%), Positives = 102/240 (42%), Gaps = 4/240 (1%)
Query: 42 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 101
+V ++++ E++L K + ++A +L+E E++ + E L ++Q E +
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 102 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
+EE K E ++ E + E+R QQ + ++ Q+ + E+ +
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 972
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
++ + E +++ ED + D + ++L +E K++ + L + + ++ +
Sbjct: 973 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K+ ++L+K +LE G D ++ +AD + + AEL
Sbjct: 1033 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE---GDASDFHEQIAD-LQAQIAEL 1088
Score = 47.6 bits (108), Expect = 5e-05
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 6/206 (2%)
Query: 15 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 74
K D A T E + R +K E + + ++ A + L KN+L+Q DL
Sbjct: 1384 KKKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1442
Query: 75 EKQLTATEAEVAALNRKVQQI-EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
+ + RK Q+ E+ S + + + EA++ + + + LE
Sbjct: 1443 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1502
Query: 134 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 193
+ EE + TN++ +A + ED D+V + + +E E +++ ++ EL
Sbjct: 1503 LEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 1558
Query: 194 EEELKVVGNSLKSLEVSEEKANQRVE 219
E+EL+ ++ LEV+ + + E
Sbjct: 1559 EDELQATEDAKLRLEVNMQALKGQFE 1584
Score = 46.0 bits (104), Expect = 2e-04
Identities = 36/178 (20%), Positives = 82/178 (46%), Gaps = 8/178 (4%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
++A++ K + + QQ + +K+ + LQ++L +DL+++ + Q
Sbjct: 1394 VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL----DDLVVDLDNQRQL 1449
Query: 68 NKDLEEKEKQLTATEAEVAALNRKV----QQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+LE+K+++ AE ++ K + E + + E ++ + + L EA ++ +E
Sbjct: 1450 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEEL 1509
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
R K+L+ + D + + E + + +E+ +L +EDEL+ ED
Sbjct: 1510 ERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1567
Score = 45.2 bits (102), Expect = 3e-04
Identities = 63/287 (21%), Positives = 114/287 (39%), Gaps = 21/287 (7%)
Query: 16 DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKE 75
D + + + D RAE E LA+ E+ + K +LE+ NK L+ +
Sbjct: 1461 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1520
Query: 76 KQLTATEAEVA-----------ALNRKVQQIEEDLEKSE-ERSGTAQQKL-LEAQQSADE 122
+ L +++ +V AL ++++++ LE+ E E T KL LE A
Sbjct: 1521 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA-L 1579
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK---SDEVSRKLAFVEDELEV- 178
+ + L+ R +Q+EE+ QL QL E ED + + +KL +LE+
Sbjct: 1580 KGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQ 1639
Query: 179 AEDRVKSGDAKISE---LEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXX 235
A+ +K + I + L+ ++K L+ S ++ +E
Sbjct: 1640 ADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQL 1699
Query: 236 XXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
+ K+ E + L +EL + +L DE A +A
Sbjct: 1700 QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1746
Score = 44.0 bits (99), Expect = 6e-04
Identities = 34/196 (17%), Positives = 86/196 (43%), Gaps = 1/196 (0%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E++ + A R + + KK+ ++E + + L+ + EKQ E+
Sbjct: 1096 EEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1155
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV-LENRAQQDEERMDQL 144
AL +++ + +E +Q++ +++ DE R + ++ Q+ + +++L
Sbjct: 1156 EALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1215
Query: 145 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL 204
T QL++ + + D + ++ A + EL V + + K +LE +++ + +
Sbjct: 1216 TEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKC 1275
Query: 205 KSLEVSEEKANQRVEE 220
E + + N +V +
Sbjct: 1276 SDGERARAELNDKVHK 1291
Score = 41.9 bits (94), Expect = 0.002
Identities = 40/259 (15%), Positives = 110/259 (42%), Gaps = 10/259 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+ ++ ++ A K E + + + + ++ D R +++ E +++ +++ +EE L +
Sbjct: 914 EEMRVRLAAKKQELEEILHEMEARLEEEED---RGQQLQAERKKMAQQMLDLEEQLEEEE 970
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ + E ++ E E+ ++ + ++ ++ + EER L E ++ A
Sbjct: 971 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1030
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
++ E+ + E R+ + +E L +G + + ++A ++ ++AE
Sbjct: 1031 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ--AQIAEL 1088
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXX 241
+++ +++ EEEL+ L + A +++ E
Sbjct: 1089 KMQ-----LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNK 1143
Query: 242 XXKTVKKLQKEVDRLEDEL 260
K + L +E++ L+ EL
Sbjct: 1144 AEKQKRDLGEELEALKTEL 1162
>AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 1979
Score = 74.1 bits (174), Expect = 5e-13
Identities = 58/255 (22%), Positives = 116/255 (45%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ R+LQ++L + E +L + + A ++ E L E +
Sbjct: 1582 QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1641
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+ + ++ + L K + + Q++L +A+ S DE K E +A+ E + QL
Sbjct: 1642 SAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE 1701
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
L A + AD + +E++ +LA +D + +A+I++LEEEL+ ++++
Sbjct: 1702 DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA 1761
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
+ KA Q+ E+ + K+L+ ++ +E G K +
Sbjct: 1762 MSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEME---GAVKSK 1818
Query: 267 YKSLADEMDSTFAEL 281
+KS +++ A+L
Sbjct: 1819 FKSTIAALEAKIAQL 1833
Score = 64.5 bits (150), Expect = 4e-10
Identities = 53/229 (23%), Positives = 103/229 (44%), Gaps = 11/229 (4%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQVEEDLILN 60
+AIK+ + KD + D + +RD K NE+ + L+ L Q++EDL
Sbjct: 1649 EAIKQLRKLQAQMKDFQRELEDA--RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1706
Query: 61 KNKLEQANKDLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
+ +QA+ + EE ++L A + E L ++ Q+EE+LE+ + ++
Sbjct: 1707 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1766
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK-SDEVSRKLAFV 172
+A Q A++ + + AQ++E QL Q KE R + +G + +A +
Sbjct: 1767 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAAL 1826
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
E ++ E++V+ + + LK LK + + E + E++
Sbjct: 1827 EAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY 1875
Score = 59.3 bits (137), Expect = 2e-08
Identities = 64/284 (22%), Positives = 121/284 (42%), Gaps = 25/284 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL- 59
+ A +KKM L+ + ++ E++A L+ EKV E K+ ++E+++++
Sbjct: 948 LQAERKKMAQQMLDLEEQLE-----EEEAARQKLQLEKVTAEA-----KIKKLEDEILVM 997
Query: 60 --NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
NKL + K LEE+ LT AE K + + + K E + +L + +
Sbjct: 998 DDQNNKLSKERKLLEERISDLTTNLAEE---EEKAKNLTKLKNKHESMISELEVRLKKEE 1054
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAEDADGKSDEVSRKLAFVEDEL 176
+S E ++ + LE A E++ L Q+ E ++ LA+ K +E+ LA ++DE+
Sbjct: 1055 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK----KEEELQAALARLDDEI 1110
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXX 236
+ +K KI ELE + + L S + KA ++ +
Sbjct: 1111 AQKNNALK----KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1166
Query: 237 XXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
+ K ++EV L+ L +++ EM A+
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQ 1210
Score = 54.8 bits (126), Expect = 3e-07
Identities = 56/270 (20%), Positives = 111/270 (41%), Gaps = 14/270 (5%)
Query: 9 QAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQAN 68
+A+KL KD A + Q +D ++ + + KL Q+EE+ +++L++
Sbjct: 1309 KAIKLAKDVA-----SLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1363
Query: 69 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
+ + E+ ++ +++ +K+Q +E EE Q+++ Q +E
Sbjct: 1364 EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD 1423
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD- 187
LE + ++ +D L L R L + + K + + LA +E ++ D
Sbjct: 1424 KLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA---EEKNISSKYADERDR 1480
Query: 188 AKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVK 247
A+ E+E K + SL + E+A + EE K V
Sbjct: 1481 AEAEAREKETKAL-----SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVH 1535
Query: 248 KLQKEVDRLEDELGINKDRYKSLADEMDST 277
+L+K LE ++ K + + L DE+ +T
Sbjct: 1536 ELEKSKRALETQMEEMKTQLEELEDELQAT 1565
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/222 (20%), Positives = 105/222 (47%), Gaps = 11/222 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 1741 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 1796
Query: 64 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 1797 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1856
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 1857 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1916
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
A + ++ +++ L+ +L+ GN S S +RV E
Sbjct: 1917 ATESNEAMGREVNALKSKLR-RGNE-TSFVPSRRSGGRRVIE 1956
Score = 53.6 bits (123), Expect = 8e-07
Identities = 66/287 (22%), Positives = 122/287 (42%), Gaps = 24/287 (8%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-------AQVEEDL 57
+++MQA + E ++ E + ++ + ++ EE LQ++L A+ EE
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 58 ILNKNKLEQANKDLEEKEKQLTATE---AEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
+ K ++ + L E E +L E ++ A +K+ Q DLE+ E A+QKL
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 977
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
+ +A+ K LE+ MD N+L + R L E+ + +++ LA E+
Sbjct: 978 LEKVTAEAK---IKKLEDEILV----MDDQNNKLSKERKLLEE---RISDLTTNLAEEEE 1027
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXX 234
+ + ++ ISELE LK S + LE + K +F
Sbjct: 1028 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF---HEQIADLQAQ 1084
Query: 235 XXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K ++LQ + RL+DE+ + K + E++ ++L
Sbjct: 1085 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR-ELEGHISDL 1130
Score = 52.4 bits (120), Expect = 2e-06
Identities = 48/272 (17%), Positives = 125/272 (45%), Gaps = 28/272 (10%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQ----QARDANLRAEKVNEEVR-------ELQKKLAQVE 54
++++A+K E ++ +D T ++ + ++ + + ++EE R E+++K AQ
Sbjct: 1153 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1212
Query: 55 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
E+L + ++A +L++ ++ L A++A R + Q ++++E ++K L
Sbjct: 1213 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEH--------KKKKL 1264
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
EAQ E C E + +++ +L N+++ + +A+GK+ ++++ +A +
Sbjct: 1265 EAQ--VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1322
Query: 175 ELEVAEDRVK-------SGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXX 227
+L+ ++ ++ + K+ +LEEE + + L +++ + +
Sbjct: 1323 QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 1382
Query: 228 XXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE 259
+ K+ QKE++ L +
Sbjct: 1383 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1414
Score = 51.6 bits (118), Expect = 3e-06
Identities = 65/304 (21%), Positives = 133/304 (43%), Gaps = 32/304 (10%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D K++ A +K D D E QA A E+ +++R+LQ ++ + +L +
Sbjct: 1614 DERKQRALAAAAKKKLEGDLKDL-ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1672
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE-----DLEKSEERSGTA------- 109
++ +E EK+ + EA++ L + E DLEK E A
Sbjct: 1673 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1732
Query: 110 ----QQKLLEA-----QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+++ LEA ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 1733 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1792
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSG--------DAKISELEEELKVVGNSLKSLEVSEE 212
++ R+ + +L E VKS +AKI++LEE+++ ++ S +
Sbjct: 1793 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1852
Query: 213 KANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE-LGINKDRYKSLA 271
+ +++++E VK+L+++++ E+E IN +R K L
Sbjct: 1853 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRK-LQ 1911
Query: 272 DEMD 275
E+D
Sbjct: 1912 RELD 1915
Score = 50.8 bits (116), Expect = 5e-06
Identities = 37/217 (17%), Positives = 92/217 (42%), Gaps = 2/217 (0%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 1348 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1407
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 122
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 1408 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1467
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
N K + R + + E ++ T L AR L E + K +E+ R ++ E+E
Sbjct: 1468 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 1526
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ ELE+ + + ++ ++ E+ ++
Sbjct: 1527 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQ 1563
Score = 48.8 bits (111), Expect = 2e-05
Identities = 48/216 (22%), Positives = 103/216 (47%), Gaps = 18/216 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 60
+K +M+ + KD+ E+ R + E++ ++ EL+ +L E+ L +N
Sbjct: 1516 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1575
Query: 61 KNKLE-QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL--EKSEERSGTAQQKLLEAQ 117
L+ Q +DL+ +++Q E + L R++ + E +L E+ + A +K LE
Sbjct: 1576 MQALKGQFERDLQARDEQ---NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD 1632
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
D + ++ R ++ +++ +L Q+K+ + EDA DE+ A ++
Sbjct: 1633 LK-DLELQADSAIKGR-EEAIKQLRKLQAQMKDFQRELEDARASRDEI---FATAKEN-- 1685
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E + KS +A + +L+E+L + K ++ +E+
Sbjct: 1686 --EKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 1719
Score = 48.4 bits (110), Expect = 3e-05
Identities = 43/240 (17%), Positives = 102/240 (42%), Gaps = 4/240 (1%)
Query: 42 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 101
+V ++++ E++L K + ++A +L+E E++ + E L ++Q E +
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 102 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
+EE K E ++ E + E+R QQ + ++ Q+ + E+ +
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 972
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
++ + E +++ ED + D + ++L +E K++ + L + + ++ +
Sbjct: 973 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K+ ++L+K +LE G D ++ +AD + + AEL
Sbjct: 1033 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE---GDASDFHEQIAD-LQAQIAEL 1088
Score = 47.6 bits (108), Expect = 5e-05
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 6/206 (2%)
Query: 15 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 74
K D A T E + R +K E + + ++ A + L KN+L+Q DL
Sbjct: 1384 KKKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1442
Query: 75 EKQLTATEAEVAALNRKVQQI-EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
+ + RK Q+ E+ S + + + EA++ + + + LE
Sbjct: 1443 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1502
Query: 134 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 193
+ EE + TN++ +A + ED D+V + + +E E +++ ++ EL
Sbjct: 1503 LEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 1558
Query: 194 EEELKVVGNSLKSLEVSEEKANQRVE 219
E+EL+ ++ LEV+ + + E
Sbjct: 1559 EDELQATEDAKLRLEVNMQALKGQFE 1584
Score = 46.0 bits (104), Expect = 2e-04
Identities = 36/178 (20%), Positives = 82/178 (46%), Gaps = 8/178 (4%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
++A++ K + + QQ + +K+ + LQ++L +DL+++ + Q
Sbjct: 1394 VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL----DDLVVDLDNQRQL 1449
Query: 68 NKDLEEKEKQLTATEAEVAALNRKV----QQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+LE+K+++ AE ++ K + E + + E ++ + + L EA ++ +E
Sbjct: 1450 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEEL 1509
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
R K+L+ + D + + E + + +E+ +L +EDEL+ ED
Sbjct: 1510 ERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1567
Score = 45.2 bits (102), Expect = 3e-04
Identities = 63/287 (21%), Positives = 114/287 (39%), Gaps = 21/287 (7%)
Query: 16 DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKE 75
D + + + D RAE E LA+ E+ + K +LE+ NK L+ +
Sbjct: 1461 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1520
Query: 76 KQLTATEAEVA-----------ALNRKVQQIEEDLEKSE-ERSGTAQQKL-LEAQQSADE 122
+ L +++ +V AL ++++++ LE+ E E T KL LE A
Sbjct: 1521 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA-L 1579
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK---SDEVSRKLAFVEDELEV- 178
+ + L+ R +Q+EE+ QL QL E ED + + +KL +LE+
Sbjct: 1580 KGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQ 1639
Query: 179 AEDRVKSGDAKISE---LEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXX 235
A+ +K + I + L+ ++K L+ S ++ +E
Sbjct: 1640 ADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQL 1699
Query: 236 XXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
+ K+ E + L +EL + +L DE A +A
Sbjct: 1700 QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1746
Score = 44.0 bits (99), Expect = 6e-04
Identities = 34/196 (17%), Positives = 86/196 (43%), Gaps = 1/196 (0%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E++ + A R + + KK+ ++E + + L+ + EKQ E+
Sbjct: 1096 EEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1155
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV-LENRAQQDEERMDQL 144
AL +++ + +E +Q++ +++ DE R + ++ Q+ + +++L
Sbjct: 1156 EALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1215
Query: 145 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL 204
T QL++ + + D + ++ A + EL V + + K +LE +++ + +
Sbjct: 1216 TEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKC 1275
Query: 205 KSLEVSEEKANQRVEE 220
E + + N +V +
Sbjct: 1276 SDGERARAELNDKVHK 1291
Score = 41.9 bits (94), Expect = 0.002
Identities = 40/259 (15%), Positives = 110/259 (42%), Gaps = 10/259 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+ ++ ++ A K E + + + + ++ D R +++ E +++ +++ +EE L +
Sbjct: 914 EEMRVRLAAKKQELEEILHEMEARLEEEED---RGQQLQAERKKMAQQMLDLEEQLEEEE 970
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ + E ++ E E+ ++ + ++ ++ + EER L E ++ A
Sbjct: 971 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1030
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
++ E+ + E R+ + +E L +G + + ++A ++ ++AE
Sbjct: 1031 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ--AQIAEL 1088
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXX 241
+++ +++ EEEL+ L + A +++ E
Sbjct: 1089 KMQ-----LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNK 1143
Query: 242 XXKTVKKLQKEVDRLEDEL 260
K + L +E++ L+ EL
Sbjct: 1144 AEKQKRDLGEELEALKTEL 1162
>AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY11)
(5'partial) protein.
Length = 1857
Score = 74.1 bits (174), Expect = 5e-13
Identities = 58/255 (22%), Positives = 116/255 (45%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ R+LQ++L + E +L + + A ++ E L E +
Sbjct: 1460 QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1519
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+ + ++ + L K + + Q++L +A+ S DE K E +A+ E + QL
Sbjct: 1520 SAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE 1579
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
L A + AD + +E++ +LA +D + +A+I++LEEEL+ ++++
Sbjct: 1580 DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA 1639
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
+ KA Q+ E+ + K+L+ ++ +E G K +
Sbjct: 1640 MSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEME---GAVKSK 1696
Query: 267 YKSLADEMDSTFAEL 281
+KS +++ A+L
Sbjct: 1697 FKSTIAALEAKIAQL 1711
Score = 64.5 bits (150), Expect = 4e-10
Identities = 53/229 (23%), Positives = 103/229 (44%), Gaps = 11/229 (4%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQVEEDLILN 60
+AIK+ + KD + D + +RD K NE+ + L+ L Q++EDL
Sbjct: 1527 EAIKQLRKLQAQMKDFQRELEDA--RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1584
Query: 61 KNKLEQANKDLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
+ +QA+ + EE ++L A + E L ++ Q+EE+LE+ + ++
Sbjct: 1585 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1644
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK-SDEVSRKLAFV 172
+A Q A++ + + AQ++E QL Q KE R + +G + +A +
Sbjct: 1645 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAAL 1704
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
E ++ E++V+ + + LK LK + + E + E++
Sbjct: 1705 EAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY 1753
Score = 59.3 bits (137), Expect = 2e-08
Identities = 64/284 (22%), Positives = 121/284 (42%), Gaps = 25/284 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL- 59
+ A +KKM L+ + ++ E++A L+ EKV E K+ ++E+++++
Sbjct: 826 LQAERKKMAQQMLDLEEQLE-----EEEAARQKLQLEKVTAEA-----KIKKLEDEILVM 875
Query: 60 --NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
NKL + K LEE+ LT AE K + + + K E + +L + +
Sbjct: 876 DDQNNKLSKERKLLEERISDLTTNLAEE---EEKAKNLTKLKNKHESMISELEVRLKKEE 932
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAEDADGKSDEVSRKLAFVEDEL 176
+S E ++ + LE A E++ L Q+ E ++ LA+ K +E+ LA ++DE+
Sbjct: 933 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK----KEEELQAALARLDDEI 988
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXX 236
+ +K KI ELE + + L S + KA ++ +
Sbjct: 989 AQKNNALK----KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1044
Query: 237 XXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
+ K ++EV L+ L +++ EM A+
Sbjct: 1045 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQ 1088
Score = 54.8 bits (126), Expect = 3e-07
Identities = 56/270 (20%), Positives = 111/270 (41%), Gaps = 14/270 (5%)
Query: 9 QAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQAN 68
+A+KL KD A + Q +D ++ + + KL Q+EE+ +++L++
Sbjct: 1187 KAIKLAKDVA-----SLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1241
Query: 69 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
+ + E+ ++ +++ +K+Q +E EE Q+++ Q +E
Sbjct: 1242 EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD 1301
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD- 187
LE + ++ +D L L R L + + K + + LA +E ++ D
Sbjct: 1302 KLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA---EEKNISSKYADERDR 1358
Query: 188 AKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVK 247
A+ E+E K + SL + E+A + EE K V
Sbjct: 1359 AEAEAREKETKAL-----SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVH 1413
Query: 248 KLQKEVDRLEDELGINKDRYKSLADEMDST 277
+L+K LE ++ K + + L DE+ +T
Sbjct: 1414 ELEKSKRALETQMEEMKTQLEELEDELQAT 1443
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/222 (20%), Positives = 105/222 (47%), Gaps = 11/222 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 1619 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 1674
Query: 64 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 1675 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1734
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 1735 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1794
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
A + ++ +++ L+ +L+ GN S S +RV E
Sbjct: 1795 ATESNEAMGREVNALKSKLR-RGNE-TSFVPSRRSGGRRVIE 1834
Score = 53.6 bits (123), Expect = 8e-07
Identities = 66/287 (22%), Positives = 122/287 (42%), Gaps = 24/287 (8%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-------AQVEEDL 57
+++MQA + E ++ E + ++ + ++ EE LQ++L A+ EE
Sbjct: 736 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 795
Query: 58 ILNKNKLEQANKDLEEKEKQLTATE---AEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
+ K ++ + L E E +L E ++ A +K+ Q DLE+ E A+QKL
Sbjct: 796 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 855
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
+ +A+ K LE+ MD N+L + R L E+ + +++ LA E+
Sbjct: 856 LEKVTAEAK---IKKLEDEILV----MDDQNNKLSKERKLLEE---RISDLTTNLAEEEE 905
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXX 234
+ + ++ ISELE LK S + LE + K +F
Sbjct: 906 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF---HEQIADLQAQ 962
Query: 235 XXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K ++LQ + RL+DE+ + K + E++ ++L
Sbjct: 963 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR-ELEGHISDL 1008
Score = 52.4 bits (120), Expect = 2e-06
Identities = 48/272 (17%), Positives = 125/272 (45%), Gaps = 28/272 (10%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQ----QARDANLRAEKVNEEVR-------ELQKKLAQVE 54
++++A+K E ++ +D T ++ + ++ + + ++EE R E+++K AQ
Sbjct: 1031 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1090
Query: 55 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
E+L + ++A +L++ ++ L A++A R + Q ++++E ++K L
Sbjct: 1091 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEH--------KKKKL 1142
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
EAQ E C E + +++ +L N+++ + +A+GK+ ++++ +A +
Sbjct: 1143 EAQ--VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1200
Query: 175 ELEVAEDRVK-------SGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXX 227
+L+ ++ ++ + K+ +LEEE + + L +++ + +
Sbjct: 1201 QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 1260
Query: 228 XXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE 259
+ K+ QKE++ L +
Sbjct: 1261 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1292
Score = 51.6 bits (118), Expect = 3e-06
Identities = 65/304 (21%), Positives = 133/304 (43%), Gaps = 32/304 (10%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D K++ A +K D D E QA A E+ +++R+LQ ++ + +L +
Sbjct: 1492 DERKQRALAAAAKKKLEGDLKDL-ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1550
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE-----DLEKSEERSGTA------- 109
++ +E EK+ + EA++ L + E DLEK E A
Sbjct: 1551 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1610
Query: 110 ----QQKLLEA-----QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+++ LEA ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 1611 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1670
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSG--------DAKISELEEELKVVGNSLKSLEVSEE 212
++ R+ + +L E VKS +AKI++LEE+++ ++ S +
Sbjct: 1671 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1730
Query: 213 KANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE-LGINKDRYKSLA 271
+ +++++E VK+L+++++ E+E IN +R K L
Sbjct: 1731 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRK-LQ 1789
Query: 272 DEMD 275
E+D
Sbjct: 1790 RELD 1793
Score = 50.8 bits (116), Expect = 5e-06
Identities = 37/217 (17%), Positives = 92/217 (42%), Gaps = 2/217 (0%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 1226 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1285
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 122
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 1286 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1345
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
N K + R + + E ++ T L AR L E + K +E+ R ++ E+E
Sbjct: 1346 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 1404
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ ELE+ + + ++ ++ E+ ++
Sbjct: 1405 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQ 1441
Score = 48.8 bits (111), Expect = 2e-05
Identities = 48/216 (22%), Positives = 103/216 (47%), Gaps = 18/216 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 60
+K +M+ + KD+ E+ R + E++ ++ EL+ +L E+ L +N
Sbjct: 1394 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1453
Query: 61 KNKLE-QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL--EKSEERSGTAQQKLLEAQ 117
L+ Q +DL+ +++Q E + L R++ + E +L E+ + A +K LE
Sbjct: 1454 MQALKGQFERDLQARDEQ---NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD 1510
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
D + ++ R ++ +++ +L Q+K+ + EDA DE+ A ++
Sbjct: 1511 LK-DLELQADSAIKGR-EEAIKQLRKLQAQMKDFQRELEDARASRDEI---FATAKEN-- 1563
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E + KS +A + +L+E+L + K ++ +E+
Sbjct: 1564 --EKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 1597
Score = 48.4 bits (110), Expect = 3e-05
Identities = 43/240 (17%), Positives = 102/240 (42%), Gaps = 4/240 (1%)
Query: 42 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 101
+V ++++ E++L K + ++A +L+E E++ + E L ++Q E +
Sbjct: 731 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 790
Query: 102 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
+EE K E ++ E + E+R QQ + ++ Q+ + E+ +
Sbjct: 791 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 850
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
++ + E +++ ED + D + ++L +E K++ + L + + ++ +
Sbjct: 851 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 910
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K+ ++L+K +LE G D ++ +AD + + AEL
Sbjct: 911 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE---GDASDFHEQIAD-LQAQIAEL 966
Score = 47.6 bits (108), Expect = 5e-05
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 6/206 (2%)
Query: 15 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 74
K D A T E + R +K E + + ++ A + L KN+L+Q DL
Sbjct: 1262 KKKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1320
Query: 75 EKQLTATEAEVAALNRKVQQI-EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
+ + RK Q+ E+ S + + + EA++ + + + LE
Sbjct: 1321 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1380
Query: 134 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 193
+ EE + TN++ +A + ED D+V + + +E E +++ ++ EL
Sbjct: 1381 LEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 1436
Query: 194 EEELKVVGNSLKSLEVSEEKANQRVE 219
E+EL+ ++ LEV+ + + E
Sbjct: 1437 EDELQATEDAKLRLEVNMQALKGQFE 1462
Score = 46.0 bits (104), Expect = 2e-04
Identities = 36/178 (20%), Positives = 82/178 (46%), Gaps = 8/178 (4%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
++A++ K + + QQ + +K+ + LQ++L +DL+++ + Q
Sbjct: 1272 VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL----DDLVVDLDNQRQL 1327
Query: 68 NKDLEEKEKQLTATEAEVAALNRKV----QQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+LE+K+++ AE ++ K + E + + E ++ + + L EA ++ +E
Sbjct: 1328 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEEL 1387
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
R K+L+ + D + + E + + +E+ +L +EDEL+ ED
Sbjct: 1388 ERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1445
Score = 45.2 bits (102), Expect = 3e-04
Identities = 63/287 (21%), Positives = 114/287 (39%), Gaps = 21/287 (7%)
Query: 16 DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKE 75
D + + + D RAE E LA+ E+ + K +LE+ NK L+ +
Sbjct: 1339 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1398
Query: 76 KQLTATEAEVA-----------ALNRKVQQIEEDLEKSE-ERSGTAQQKL-LEAQQSADE 122
+ L +++ +V AL ++++++ LE+ E E T KL LE A
Sbjct: 1399 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA-L 1457
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK---SDEVSRKLAFVEDELEV- 178
+ + L+ R +Q+EE+ QL QL E ED + + +KL +LE+
Sbjct: 1458 KGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQ 1517
Query: 179 AEDRVKSGDAKISE---LEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXX 235
A+ +K + I + L+ ++K L+ S ++ +E
Sbjct: 1518 ADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQL 1577
Query: 236 XXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
+ K+ E + L +EL + +L DE A +A
Sbjct: 1578 QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1624
Score = 44.0 bits (99), Expect = 6e-04
Identities = 34/196 (17%), Positives = 86/196 (43%), Gaps = 1/196 (0%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E++ + A R + + KK+ ++E + + L+ + EKQ E+
Sbjct: 974 EEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1033
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV-LENRAQQDEERMDQL 144
AL +++ + +E +Q++ +++ DE R + ++ Q+ + +++L
Sbjct: 1034 EALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1093
Query: 145 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL 204
T QL++ + + D + ++ A + EL V + + K +LE +++ + +
Sbjct: 1094 TEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKC 1153
Query: 205 KSLEVSEEKANQRVEE 220
E + + N +V +
Sbjct: 1154 SDGERARAELNDKVHK 1169
Score = 41.9 bits (94), Expect = 0.002
Identities = 40/259 (15%), Positives = 110/259 (42%), Gaps = 10/259 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+ ++ ++ A K E + + + + ++ D R +++ E +++ +++ +EE L +
Sbjct: 792 EEMRVRLAAKKQELEEILHEMEARLEEEED---RGQQLQAERKKMAQQMLDLEEQLEEEE 848
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ + E ++ E E+ ++ + ++ ++ + EER L E ++ A
Sbjct: 849 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 908
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
++ E+ + E R+ + +E L +G + + ++A ++ ++AE
Sbjct: 909 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ--AQIAEL 966
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXX 241
+++ +++ EEEL+ L + A +++ E
Sbjct: 967 KMQ-----LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNK 1021
Query: 242 XXKTVKKLQKEVDRLEDEL 260
K + L +E++ L+ EL
Sbjct: 1022 AEKQKRDLGEELEALKTEL 1040
>AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein.
Length = 1984
Score = 74.1 bits (174), Expect = 5e-13
Identities = 58/255 (22%), Positives = 116/255 (45%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ R+LQ++L + E +L + + A ++ E L E +
Sbjct: 1587 QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1646
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+ + ++ + L K + + Q++L +A+ S DE K E +A+ E + QL
Sbjct: 1647 SAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE 1706
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
L A + AD + +E++ +LA +D + +A+I++LEEEL+ ++++
Sbjct: 1707 DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA 1766
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
+ KA Q+ E+ + K+L+ ++ +E G K +
Sbjct: 1767 MSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEME---GAVKSK 1823
Query: 267 YKSLADEMDSTFAEL 281
+KS +++ A+L
Sbjct: 1824 FKSTIAALEAKIAQL 1838
Score = 64.5 bits (150), Expect = 4e-10
Identities = 53/229 (23%), Positives = 103/229 (44%), Gaps = 11/229 (4%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQVEEDLILN 60
+AIK+ + KD + D + +RD K NE+ + L+ L Q++EDL
Sbjct: 1654 EAIKQLRKLQAQMKDFQRELEDA--RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1711
Query: 61 KNKLEQANKDLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
+ +QA+ + EE ++L A + E L ++ Q+EE+LE+ + ++
Sbjct: 1712 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1771
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK-SDEVSRKLAFV 172
+A Q A++ + + AQ++E QL Q KE R + +G + +A +
Sbjct: 1772 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAAL 1831
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
E ++ E++V+ + + LK LK + + E + E++
Sbjct: 1832 EAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY 1880
Score = 59.3 bits (137), Expect = 2e-08
Identities = 64/284 (22%), Positives = 121/284 (42%), Gaps = 25/284 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL- 59
+ A +KKM L+ + ++ E++A L+ EKV E K+ ++E+++++
Sbjct: 953 LQAERKKMAQQMLDLEEQLE-----EEEAARQKLQLEKVTAEA-----KIKKLEDEILVM 1002
Query: 60 --NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
NKL + K LEE+ LT AE K + + + K E + +L + +
Sbjct: 1003 DDQNNKLSKERKLLEERISDLTTNLAEE---EEKAKNLTKLKNKHESMISELEVRLKKEE 1059
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAEDADGKSDEVSRKLAFVEDEL 176
+S E ++ + LE A E++ L Q+ E ++ LA+ K +E+ LA ++DE+
Sbjct: 1060 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK----KEEELQAALARLDDEI 1115
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXX 236
+ +K KI ELE + + L S + KA ++ +
Sbjct: 1116 AQKNNALK----KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1171
Query: 237 XXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
+ K ++EV L+ L +++ EM A+
Sbjct: 1172 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQ 1215
Score = 54.8 bits (126), Expect = 3e-07
Identities = 56/270 (20%), Positives = 111/270 (41%), Gaps = 14/270 (5%)
Query: 9 QAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQAN 68
+A+KL KD A + Q +D ++ + + KL Q+EE+ +++L++
Sbjct: 1314 KAIKLAKDVA-----SLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEM 1368
Query: 69 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
+ + E+ ++ +++ +K+Q +E EE Q+++ Q +E
Sbjct: 1369 EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD 1428
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD- 187
LE + ++ +D L L R L + + K + + LA +E ++ D
Sbjct: 1429 KLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA---EEKNISSKYADERDR 1485
Query: 188 AKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVK 247
A+ E+E K + SL + E+A + EE K V
Sbjct: 1486 AEAEAREKETKAL-----SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVH 1540
Query: 248 KLQKEVDRLEDELGINKDRYKSLADEMDST 277
+L+K LE ++ K + + L DE+ +T
Sbjct: 1541 ELEKSKRALETQMEEMKTQLEELEDELQAT 1570
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/222 (20%), Positives = 105/222 (47%), Gaps = 11/222 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 1746 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 1801
Query: 64 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 1802 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1861
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 1862 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1921
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
A + ++ +++ L+ +L+ GN S S +RV E
Sbjct: 1922 ATESNEAMGREVNALKSKLR-RGNE-TSFVPSRRSGGRRVIE 1961
Score = 53.6 bits (123), Expect = 8e-07
Identities = 66/287 (22%), Positives = 122/287 (42%), Gaps = 24/287 (8%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-------AQVEEDL 57
+++MQA + E ++ E + ++ + ++ EE LQ++L A+ EE
Sbjct: 863 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 922
Query: 58 ILNKNKLEQANKDLEEKEKQLTATE---AEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
+ K ++ + L E E +L E ++ A +K+ Q DLE+ E A+QKL
Sbjct: 923 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 982
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
+ +A+ K LE+ MD N+L + R L E+ + +++ LA E+
Sbjct: 983 LEKVTAEAK---IKKLEDEILV----MDDQNNKLSKERKLLEE---RISDLTTNLAEEEE 1032
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXX 234
+ + ++ ISELE LK S + LE + K +F
Sbjct: 1033 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF---HEQIADLQAQ 1089
Query: 235 XXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K ++LQ + RL+DE+ + K + E++ ++L
Sbjct: 1090 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR-ELEGHISDL 1135
Score = 52.4 bits (120), Expect = 2e-06
Identities = 48/272 (17%), Positives = 125/272 (45%), Gaps = 28/272 (10%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQ----QARDANLRAEKVNEEVR-------ELQKKLAQVE 54
++++A+K E ++ +D T ++ + ++ + + ++EE R E+++K AQ
Sbjct: 1158 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1217
Query: 55 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
E+L + ++A +L++ ++ L A++A R + Q ++++E ++K L
Sbjct: 1218 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEH--------KKKKL 1269
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
EAQ E C E + +++ +L N+++ + +A+GK+ ++++ +A +
Sbjct: 1270 EAQ--VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1327
Query: 175 ELEVAEDRVK-------SGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXX 227
+L+ ++ ++ + K+ +LEEE + + L +++ + +
Sbjct: 1328 QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 1387
Query: 228 XXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE 259
+ K+ QKE++ L +
Sbjct: 1388 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1419
Score = 51.6 bits (118), Expect = 3e-06
Identities = 65/304 (21%), Positives = 133/304 (43%), Gaps = 32/304 (10%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D K++ A +K D D E QA A E+ +++R+LQ ++ + +L +
Sbjct: 1619 DERKQRALAAAAKKKLEGDLKDL-ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1677
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE-----DLEKSEERSGTA------- 109
++ +E EK+ + EA++ L + E DLEK E A
Sbjct: 1678 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1737
Query: 110 ----QQKLLEA-----QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+++ LEA ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 1738 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1797
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSG--------DAKISELEEELKVVGNSLKSLEVSEE 212
++ R+ + +L E VKS +AKI++LEE+++ ++ S +
Sbjct: 1798 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1857
Query: 213 KANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE-LGINKDRYKSLA 271
+ +++++E VK+L+++++ E+E IN +R K L
Sbjct: 1858 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRK-LQ 1916
Query: 272 DEMD 275
E+D
Sbjct: 1917 RELD 1920
Score = 50.8 bits (116), Expect = 5e-06
Identities = 37/217 (17%), Positives = 92/217 (42%), Gaps = 2/217 (0%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 1353 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1412
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 122
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 1413 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1472
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
N K + R + + E ++ T L AR L E + K +E+ R ++ E+E
Sbjct: 1473 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 1531
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ ELE+ + + ++ ++ E+ ++
Sbjct: 1532 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQ 1568
Score = 48.8 bits (111), Expect = 2e-05
Identities = 48/216 (22%), Positives = 103/216 (47%), Gaps = 18/216 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 60
+K +M+ + KD+ E+ R + E++ ++ EL+ +L E+ L +N
Sbjct: 1521 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 1580
Query: 61 KNKLE-QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL--EKSEERSGTAQQKLLEAQ 117
L+ Q +DL+ +++Q E + L R++ + E +L E+ + A +K LE
Sbjct: 1581 MQALKGQFERDLQARDEQ---NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD 1637
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
D + ++ R ++ +++ +L Q+K+ + EDA DE+ A ++
Sbjct: 1638 LK-DLELQADSAIKGR-EEAIKQLRKLQAQMKDFQRELEDARASRDEI---FATAKEN-- 1690
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E + KS +A + +L+E+L + K ++ +E+
Sbjct: 1691 --EKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 1724
Score = 48.4 bits (110), Expect = 3e-05
Identities = 43/240 (17%), Positives = 102/240 (42%), Gaps = 4/240 (1%)
Query: 42 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 101
+V ++++ E++L K + ++A +L+E E++ + E L ++Q E +
Sbjct: 858 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 917
Query: 102 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
+EE K E ++ E + E+R QQ + ++ Q+ + E+ +
Sbjct: 918 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 977
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
++ + E +++ ED + D + ++L +E K++ + L + + ++ +
Sbjct: 978 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1037
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K+ ++L+K +LE G D ++ +AD + + AEL
Sbjct: 1038 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE---GDASDFHEQIAD-LQAQIAEL 1093
Score = 47.6 bits (108), Expect = 5e-05
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 6/206 (2%)
Query: 15 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 74
K D A T E + R +K E + + ++ A + L KN+L+Q DL
Sbjct: 1389 KKKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1447
Query: 75 EKQLTATEAEVAALNRKVQQI-EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
+ + RK Q+ E+ S + + + EA++ + + + LE
Sbjct: 1448 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 1507
Query: 134 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 193
+ EE + TN++ +A + ED D+V + + +E E +++ ++ EL
Sbjct: 1508 LEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 1563
Query: 194 EEELKVVGNSLKSLEVSEEKANQRVE 219
E+EL+ ++ LEV+ + + E
Sbjct: 1564 EDELQATEDAKLRLEVNMQALKGQFE 1589
Score = 46.0 bits (104), Expect = 2e-04
Identities = 36/178 (20%), Positives = 82/178 (46%), Gaps = 8/178 (4%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
++A++ K + + QQ + +K+ + LQ++L +DL+++ + Q
Sbjct: 1399 VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL----DDLVVDLDNQRQL 1454
Query: 68 NKDLEEKEKQLTATEAEVAALNRKV----QQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+LE+K+++ AE ++ K + E + + E ++ + + L EA ++ +E
Sbjct: 1455 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEEL 1514
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
R K+L+ + D + + E + + +E+ +L +EDEL+ ED
Sbjct: 1515 ERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1572
Score = 45.2 bits (102), Expect = 3e-04
Identities = 63/287 (21%), Positives = 114/287 (39%), Gaps = 21/287 (7%)
Query: 16 DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKE 75
D + + + D RAE E LA+ E+ + K +LE+ NK L+ +
Sbjct: 1466 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1525
Query: 76 KQLTATEAEVA-----------ALNRKVQQIEEDLEKSE-ERSGTAQQKL-LEAQQSADE 122
+ L +++ +V AL ++++++ LE+ E E T KL LE A
Sbjct: 1526 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA-L 1584
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK---SDEVSRKLAFVEDELEV- 178
+ + L+ R +Q+EE+ QL QL E ED + + +KL +LE+
Sbjct: 1585 KGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQ 1644
Query: 179 AEDRVKSGDAKISE---LEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXX 235
A+ +K + I + L+ ++K L+ S ++ +E
Sbjct: 1645 ADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQL 1704
Query: 236 XXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
+ K+ E + L +EL + +L DE A +A
Sbjct: 1705 QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA 1751
Score = 44.0 bits (99), Expect = 6e-04
Identities = 34/196 (17%), Positives = 86/196 (43%), Gaps = 1/196 (0%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E++ + A R + + KK+ ++E + + L+ + EKQ E+
Sbjct: 1101 EEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1160
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV-LENRAQQDEERMDQL 144
AL +++ + +E +Q++ +++ DE R + ++ Q+ + +++L
Sbjct: 1161 EALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1220
Query: 145 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL 204
T QL++ + + D + ++ A + EL V + + K +LE +++ + +
Sbjct: 1221 TEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKC 1280
Query: 205 KSLEVSEEKANQRVEE 220
E + + N +V +
Sbjct: 1281 SDGERARAELNDKVHK 1296
Score = 41.9 bits (94), Expect = 0.002
Identities = 40/259 (15%), Positives = 110/259 (42%), Gaps = 10/259 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+ ++ ++ A K E + + + + ++ D R +++ E +++ +++ +EE L +
Sbjct: 919 EEMRVRLAAKKQELEEILHEMEARLEEEED---RGQQLQAERKKMAQQMLDLEEQLEEEE 975
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ + E ++ E E+ ++ + ++ ++ + EER L E ++ A
Sbjct: 976 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1035
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
++ E+ + E R+ + +E L +G + + ++A ++ ++AE
Sbjct: 1036 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQ--AQIAEL 1093
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXX 241
+++ +++ EEEL+ L + A +++ E
Sbjct: 1094 KMQ-----LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNK 1148
Query: 242 XXKTVKKLQKEVDRLEDEL 260
K + L +E++ L+ EL
Sbjct: 1149 AEKQKRDLGEELEALKTEL 1167
>BX537964-1|CAD97928.1| 898|Homo sapiens hypothetical protein
protein.
Length = 898
Score = 73.7 bits (173), Expect = 7e-13
Identities = 66/281 (23%), Positives = 118/281 (41%), Gaps = 13/281 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M+ KK + + EK+ + K E+++ D LR EK L+KKL ++L N
Sbjct: 294 MEQANKKCEEARQEKEAMVMKYVRGEKESLD--LRKEK-----ETLEKKLRDANKELEKN 346
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
NK++Q +++ + E E L R++ +++ED+ + AQ KL S
Sbjct: 347 TNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSH 406
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKE-ARLLAEDADGKSDEVSRKLAFVEDELE-- 177
E K + Q +E DQ+ ++ + E + KS+E+ KL + ELE
Sbjct: 407 KETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQ 466
Query: 178 --VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXX 235
D+++ AKI ELE+ + + L K +E
Sbjct: 467 MQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEII 526
Query: 236 XXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
+ K+ K D+L+++L K ++L +E++S
Sbjct: 527 NRQKAEIQNLLDKV-KTADQLQEQLQRGKQEIENLKEEVES 566
Score = 51.6 bits (118), Expect = 3e-06
Identities = 43/228 (18%), Positives = 107/228 (46%), Gaps = 15/228 (6%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQQAR---DANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
K+++ +K MD+ T + + D LR E + +E+ + ++L+
Sbjct: 482 KELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVK 541
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG-----TAQQKLLEAQ 117
+Q + L+ ++++ + EV +LN + +++D+E S +R T + AQ
Sbjct: 542 TADQLQEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQ 601
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR-KLAFVEDEL 176
++ N+ + ++ E ++ Q+K+ + E K +E+ + ++ ++ EL
Sbjct: 602 LQSESNSLQSQF--DKVSCSESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAEL 659
Query: 177 EVAEDRVKSGDAKISELEEEL----KVVGNSLKSLEVSEEKANQRVEE 220
+ VK+ ++ EL++EL + +S+K L ++A +++++
Sbjct: 660 ACRQTEVKALSTQVEELKDELVTQRRKHASSIKDLTKQLQQARRKLDQ 707
>BC105632-1|AAI05633.1| 898|Homo sapiens chromosome 10 open reading
frame 118 protein.
Length = 898
Score = 73.7 bits (173), Expect = 7e-13
Identities = 66/281 (23%), Positives = 118/281 (41%), Gaps = 13/281 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M+ KK + + EK+ + K E+++ D LR EK L+KKL ++L N
Sbjct: 294 MEQANKKCEEARQEKEAMVMKYVRGEKESLD--LRKEK-----ETLEKKLRDANKELEKN 346
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
NK++Q +++ + E E L R++ +++ED+ + AQ KL S
Sbjct: 347 TNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSH 406
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKE-ARLLAEDADGKSDEVSRKLAFVEDELE-- 177
E K + Q +E DQ+ ++ + E + KS+E+ KL + ELE
Sbjct: 407 KETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQ 466
Query: 178 --VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXX 235
D+++ AKI ELE+ + + L K +E
Sbjct: 467 MQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEII 526
Query: 236 XXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
+ K+ K D+L+++L K ++L +E++S
Sbjct: 527 NRQKAEIQNLLDKV-KTADQLQEQLQRGKQEIENLKEEVES 566
Score = 51.6 bits (118), Expect = 3e-06
Identities = 43/228 (18%), Positives = 107/228 (46%), Gaps = 15/228 (6%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQQAR---DANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
K+++ +K MD+ T + + D LR E + +E+ + ++L+
Sbjct: 482 KELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVK 541
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG-----TAQQKLLEAQ 117
+Q + L+ ++++ + EV +LN + +++D+E S +R T + AQ
Sbjct: 542 TADQLQEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQ 601
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR-KLAFVEDEL 176
++ N+ + ++ E ++ Q+K+ + E K +E+ + ++ ++ EL
Sbjct: 602 LQSESNSLQSQF--DKVSCSESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAEL 659
Query: 177 EVAEDRVKSGDAKISELEEEL----KVVGNSLKSLEVSEEKANQRVEE 220
+ VK+ ++ EL++EL + +S+K L ++A +++++
Sbjct: 660 ACRQTEVKALSTQVEELKDELVTQRRKHASSIKDLTKQLQQARRKLDQ 707
>BC103499-1|AAI03500.1| 898|Homo sapiens chromosome 10 open reading
frame 118 protein.
Length = 898
Score = 73.7 bits (173), Expect = 7e-13
Identities = 66/281 (23%), Positives = 118/281 (41%), Gaps = 13/281 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M+ KK + + EK+ + K E+++ D LR EK L+KKL ++L N
Sbjct: 294 MEQANKKCEEARQEKEAMVMKYVRGEKESLD--LRKEK-----ETLEKKLRDANKELEKN 346
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
NK++Q +++ + E E L R++ +++ED+ + AQ KL S
Sbjct: 347 TNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSH 406
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKE-ARLLAEDADGKSDEVSRKLAFVEDELE-- 177
E K + Q +E DQ+ ++ + E + KS+E+ KL + ELE
Sbjct: 407 KETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQ 466
Query: 178 --VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXX 235
D+++ AKI ELE+ + + L K +E
Sbjct: 467 MQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEII 526
Query: 236 XXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
+ K+ K D+L+++L K ++L +E++S
Sbjct: 527 NRQKAEIQNLLDKV-KTADQLQEQLQRGKQEIENLKEEVES 566
Score = 51.6 bits (118), Expect = 3e-06
Identities = 43/228 (18%), Positives = 107/228 (46%), Gaps = 15/228 (6%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQQAR---DANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
K+++ +K MD+ T + + D LR E + +E+ + ++L+
Sbjct: 482 KELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVK 541
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG-----TAQQKLLEAQ 117
+Q + L+ ++++ + EV +LN + +++D+E S +R T + AQ
Sbjct: 542 TADQLQEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQ 601
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR-KLAFVEDEL 176
++ N+ + ++ E ++ Q+K+ + E K +E+ + ++ ++ EL
Sbjct: 602 LQSESNSLQSQF--DKVSCSESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAEL 659
Query: 177 EVAEDRVKSGDAKISELEEEL----KVVGNSLKSLEVSEEKANQRVEE 220
+ VK+ ++ EL++EL + +S+K L ++A +++++
Sbjct: 660 ACRQTEVKALSTQVEELKDELVTQRRKHASSIKDLTKQLQQARRKLDQ 707
>BC100670-1|AAI00671.1| 1004|Homo sapiens C10orf118 protein protein.
Length = 1004
Score = 73.7 bits (173), Expect = 7e-13
Identities = 66/281 (23%), Positives = 118/281 (41%), Gaps = 13/281 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M+ KK + + EK+ + K E+++ D LR EK L+KKL ++L N
Sbjct: 400 MEQANKKCEEARQEKEAMVMKYVRGEKESLD--LRKEK-----ETLEKKLRDANKELEKN 452
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
NK++Q +++ + E E L R++ +++ED+ + AQ KL S
Sbjct: 453 TNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSH 512
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKE-ARLLAEDADGKSDEVSRKLAFVEDELE-- 177
E K + Q +E DQ+ ++ + E + KS+E+ KL + ELE
Sbjct: 513 KETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQ 572
Query: 178 --VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXX 235
D+++ AKI ELE+ + + L K +E
Sbjct: 573 MQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEII 632
Query: 236 XXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
+ K+ K D+L+++L K ++L +E++S
Sbjct: 633 NRQKAEIQNLLDKV-KTADQLQEQLQRGKQEIENLKEEVES 672
Score = 51.6 bits (118), Expect = 3e-06
Identities = 43/228 (18%), Positives = 107/228 (46%), Gaps = 15/228 (6%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQQAR---DANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
K+++ +K MD+ T + + D LR E + +E+ + ++L+
Sbjct: 588 KELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVK 647
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG-----TAQQKLLEAQ 117
+Q + L+ ++++ + EV +LN + +++D+E S +R T + AQ
Sbjct: 648 TADQLQEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQ 707
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR-KLAFVEDEL 176
++ N+ + ++ E ++ Q+K+ + E K +E+ + ++ ++ EL
Sbjct: 708 LQSESNSLQSQF--DKVSCSESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAEL 765
Query: 177 EVAEDRVKSGDAKISELEEEL----KVVGNSLKSLEVSEEKANQRVEE 220
+ VK+ ++ EL++EL + +S+K L ++A +++++
Sbjct: 766 ACRQTEVKALSTQVEELKDELVTQRRKHASSIKDLTKQLQQARRKLDQ 813
>AF273054-1|AAM44457.1| 613|Homo sapiens CTCL tumor antigen
HD-CL-01 protein.
Length = 613
Score = 73.7 bits (173), Expect = 7e-13
Identities = 66/281 (23%), Positives = 118/281 (41%), Gaps = 13/281 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M+ KK + + EK+ + K E+++ D LR EK L+KKL ++L N
Sbjct: 111 MEQANKKCEEARQEKEAMVMKYVRGEKESLD--LRKEK-----ETLEKKLRDANKELEKN 163
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
NK++Q +++ + E E L R++ +++ED+ + AQ KL S
Sbjct: 164 TNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSH 223
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKE-ARLLAEDADGKSDEVSRKLAFVEDELE-- 177
E K + Q +E DQ+ ++ + E + KS+E+ KL + ELE
Sbjct: 224 KETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQ 283
Query: 178 --VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXX 235
D+++ AKI ELE+ + + L K +E
Sbjct: 284 MQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEII 343
Query: 236 XXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
+ K+ K D+L+++L K ++L +E++S
Sbjct: 344 NRQKAEIQNLLDKV-KTADQLQEQLQRGKQEIENLKEEVES 383
Score = 51.6 bits (118), Expect = 3e-06
Identities = 43/228 (18%), Positives = 107/228 (46%), Gaps = 15/228 (6%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQQAR---DANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
K+++ +K MD+ T + + D LR E + +E+ + ++L+
Sbjct: 299 KELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVK 358
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG-----TAQQKLLEAQ 117
+Q + L+ ++++ + EV +LN + +++D+E S +R T + AQ
Sbjct: 359 TADQLQEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQ 418
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR-KLAFVEDEL 176
++ N+ + ++ E ++ Q+K+ + E K +E+ + ++ ++ EL
Sbjct: 419 LQSESNSLQSQF--DKVSCSESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAEL 476
Query: 177 EVAEDRVKSGDAKISELEEEL----KVVGNSLKSLEVSEEKANQRVEE 220
+ VK+ ++ EL++EL + +S+K L ++A +++++
Sbjct: 477 ACRQTEVKALSTQVEELKDELVTQRRKHASSIKDLTKQLQQARRKLDQ 524
>AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin heavy
chain SM1 protein.
Length = 622
Score = 72.5 bits (170), Expect = 2e-12
Identities = 57/255 (22%), Positives = 116/255 (45%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ R+LQ++L + E +L + + A ++ E L E +
Sbjct: 225 QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 284
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+ + ++ + + K + + Q++L +A+ S DE K E +A+ E + QL
Sbjct: 285 SAIKGREEAIKHVRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE 344
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
L A + AD + +E++ +LA +D + +A+I++LEEEL+ ++++
Sbjct: 345 DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA 404
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
+ KA Q+ E+ + K+L+ ++ +E G K +
Sbjct: 405 MSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEME---GAVKSK 461
Query: 267 YKSLADEMDSTFAEL 281
+KS +++ A+L
Sbjct: 462 FKSTIAALEAKIAQL 476
Score = 64.1 bits (149), Expect = 5e-10
Identities = 54/231 (23%), Positives = 106/231 (45%), Gaps = 15/231 (6%)
Query: 2 DAIK--KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQVEEDLI 58
+AIK +K+QA + ++ A + +RD K NE+ + L+ L Q++EDL
Sbjct: 292 EAIKHVRKLQAQMKDFQRELEDA----RASRDEIFATAKENEKKAKSLEADLMQLQEDLA 347
Query: 59 LNKNKLEQANKDLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 111
+ +QA+ + EE ++L A + E L ++ Q+EE+LE+ +
Sbjct: 348 AAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSD 407
Query: 112 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK-SDEVSRKLA 170
++ +A Q A++ + + AQ++E QL Q KE R + +G + +A
Sbjct: 408 RVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIA 467
Query: 171 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
+E ++ E++V+ + + LK LK + + E + E++
Sbjct: 468 ALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY 518
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/222 (20%), Positives = 105/222 (47%), Gaps = 11/222 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 384 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 439
Query: 64 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 440 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 499
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 500 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 559
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
A + ++ +++ L+ +L+ GN S S +RV E
Sbjct: 560 ATESNEAMGREVNALKSKLR-RGNE-TSFVPSRRSGGRRVIE 599
Score = 52.8 bits (121), Expect = 1e-06
Identities = 66/304 (21%), Positives = 138/304 (45%), Gaps = 32/304 (10%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE---EDLI 58
D K++ A +K D D E QA A E+ + VR+LQ ++ + ED
Sbjct: 257 DERKQRALAAAAKKKLEGDLKDL-ELQADSAIKGREEAIKHVRKLQAQMKDFQRELEDAR 315
Query: 59 LNKNKLEQANKDLEEKEKQLTA----TEAEVAALNRKVQQIEEDLEKSEERSGTA----- 109
+++++ K+ E+K K L A + ++AA R +Q + + E+ E ++
Sbjct: 316 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 375
Query: 110 ----QQKLLEA-----QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+++ LEA ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 376 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 435
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSG--------DAKISELEEELKVVGNSLKSLEVSEE 212
++ R+ + +L E VKS +AKI++LEE+++ ++ S +
Sbjct: 436 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 495
Query: 213 KANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE-LGINKDRYKSLA 271
+ +++++E VK+L+++++ E+E IN +R K L
Sbjct: 496 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRK-LQ 554
Query: 272 DEMD 275
E+D
Sbjct: 555 RELD 558
Score = 48.0 bits (109), Expect = 4e-05
Identities = 48/216 (22%), Positives = 102/216 (47%), Gaps = 18/216 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 60
+K +M+ + KD+ E+ R + E++ ++ EL+ +L E+ L +N
Sbjct: 159 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 218
Query: 61 KNKLE-QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL--EKSEERSGTAQQKLLEAQ 117
L+ Q +DL+ +++Q E + L R++ + E +L E+ + A +K LE
Sbjct: 219 MQALKGQFERDLQARDEQ---NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD 275
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
D + ++ R ++ + + +L Q+K+ + EDA DE+ A ++
Sbjct: 276 LK-DLELQADSAIKGR-EEAIKHVRKLQAQMKDFQRELEDARASRDEI---FATAKEN-- 328
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E + KS +A + +L+E+L + K ++ +E+
Sbjct: 329 --EKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 362
Score = 47.6 bits (108), Expect = 5e-05
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 6/206 (2%)
Query: 15 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 74
K D A T E + R +K E + + ++ A + L KN+L+Q DL
Sbjct: 27 KKKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 85
Query: 75 EKQLTATEAEVAALNRKVQQI-EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
+ + RK Q+ E+ S + + + EA++ + + + LE
Sbjct: 86 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 145
Query: 134 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 193
+ EE + TN++ +A + ED D+V + + +E E +++ ++ EL
Sbjct: 146 LEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 201
Query: 194 EEELKVVGNSLKSLEVSEEKANQRVE 219
E+EL+ ++ LEV+ + + E
Sbjct: 202 EDELQATEDAKLRLEVNMQALKGQFE 227
Score = 47.2 bits (107), Expect = 7e-05
Identities = 36/202 (17%), Positives = 83/202 (41%), Gaps = 2/202 (0%)
Query: 19 MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQL 78
M+ E+ N++ +++++ + +EE + ++E + EEK
Sbjct: 6 MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAY 65
Query: 79 TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADENNRMCKVLENRAQQD 137
E L +++ + DL+ + ++K + Q A+E N K + R + +
Sbjct: 66 DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 125
Query: 138 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 197
E ++ T L AR L E + K +E+ R ++ E+E + ELE+
Sbjct: 126 AEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 184
Query: 198 KVVGNSLKSLEVSEEKANQRVE 219
+ + ++ ++ E+ ++
Sbjct: 185 RALETQMEEMKTQLEELEDELQ 206
Score = 46.0 bits (104), Expect = 2e-04
Identities = 36/178 (20%), Positives = 82/178 (46%), Gaps = 8/178 (4%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
++A++ K + + QQ + +K+ + LQ++L +DL+++ + Q
Sbjct: 37 VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL----DDLVVDLDNQRQL 92
Query: 68 NKDLEEKEKQLTATEAEVAALNRKV----QQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+LE+K+++ AE ++ K + E + + E ++ + + L EA ++ +E
Sbjct: 93 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEEL 152
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
R K+L+ + D + + E + + +E+ +L +EDEL+ ED
Sbjct: 153 ERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 210
Score = 45.2 bits (102), Expect = 3e-04
Identities = 64/280 (22%), Positives = 110/280 (39%), Gaps = 28/280 (10%)
Query: 16 DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKE 75
D + + + D RAE E LA+ E+ + K +LE+ NK L+ +
Sbjct: 104 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 163
Query: 76 KQLTATEAEVA-----------ALNRKVQQIEEDLEKSE-ERSGTAQQKL-LEAQQSADE 122
+ L +++ +V AL ++++++ LE+ E E T KL LE A
Sbjct: 164 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA-L 222
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
+ + L+ R +Q+EE+ QL QL E ED RK + L A +
Sbjct: 223 KGQFERDLQARDEQNEEKRRQLQRQLHEYETELED--------ERK----QRALAAAAKK 270
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXX 242
GD K EL+ + + G V K ++++F
Sbjct: 271 KLEGDLKDLELQADSAIKGREEAIKHV--RKLQAQMKDFQRELEDARASRDEIFATAKEN 328
Query: 243 XKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
K K L+ ++ +L+++L + K E + ELA
Sbjct: 329 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELA 368
>AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin heavy
chain SM2 protein.
Length = 588
Score = 72.5 bits (170), Expect = 2e-12
Identities = 57/255 (22%), Positives = 116/255 (45%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ R+LQ++L + E +L + + A ++ E L E +
Sbjct: 225 QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 284
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+ + ++ + + K + + Q++L +A+ S DE K E +A+ E + QL
Sbjct: 285 SAIKGREEAIKHVRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE 344
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
L A + AD + +E++ +LA +D + +A+I++LEEEL+ ++++
Sbjct: 345 DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA 404
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
+ KA Q+ E+ + K+L+ ++ +E G K +
Sbjct: 405 MSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEME---GAVKSK 461
Query: 267 YKSLADEMDSTFAEL 281
+KS +++ A+L
Sbjct: 462 FKSTIAALEAKIAQL 476
Score = 64.9 bits (151), Expect = 3e-10
Identities = 60/293 (20%), Positives = 127/293 (43%), Gaps = 15/293 (5%)
Query: 2 DAIK--KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQVEEDLI 58
+AIK +K+QA + ++ A + +RD K NE+ + L+ L Q++EDL
Sbjct: 292 EAIKHVRKLQAQMKDFQRELEDA----RASRDEIFATAKENEKKAKSLEADLMQLQEDLA 347
Query: 59 LNKNKLEQANKDLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 111
+ +QA+ + EE ++L A + E L ++ Q+EE+LE+ +
Sbjct: 348 AAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSD 407
Query: 112 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK-SDEVSRKLA 170
++ +A Q A++ + + AQ++E QL Q KE R + +G + +A
Sbjct: 408 RVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIA 467
Query: 171 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXX 230
+E ++ E++V+ + + LK LK + + E + E++
Sbjct: 468 ALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNA 527
Query: 231 XXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAG 283
+ +++ +L+ EL + +++ E+++ ++L G
Sbjct: 528 RVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRG 580
Score = 52.8 bits (121), Expect = 1e-06
Identities = 66/304 (21%), Positives = 138/304 (45%), Gaps = 32/304 (10%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE---EDLI 58
D K++ A +K D D E QA A E+ + VR+LQ ++ + ED
Sbjct: 257 DERKQRALAAAAKKKLEGDLKDL-ELQADSAIKGREEAIKHVRKLQAQMKDFQRELEDAR 315
Query: 59 LNKNKLEQANKDLEEKEKQLTA----TEAEVAALNRKVQQIEEDLEKSEERSGTA----- 109
+++++ K+ E+K K L A + ++AA R +Q + + E+ E ++
Sbjct: 316 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 375
Query: 110 ----QQKLLEA-----QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+++ LEA ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 376 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 435
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSG--------DAKISELEEELKVVGNSLKSLEVSEE 212
++ R+ + +L E VKS +AKI++LEE+++ ++ S +
Sbjct: 436 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 495
Query: 213 KANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE-LGINKDRYKSLA 271
+ +++++E VK+L+++++ E+E IN +R K L
Sbjct: 496 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRK-LQ 554
Query: 272 DEMD 275
E+D
Sbjct: 555 RELD 558
Score = 48.0 bits (109), Expect = 4e-05
Identities = 48/216 (22%), Positives = 102/216 (47%), Gaps = 18/216 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 60
+K +M+ + KD+ E+ R + E++ ++ EL+ +L E+ L +N
Sbjct: 159 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVN 218
Query: 61 KNKLE-QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL--EKSEERSGTAQQKLLEAQ 117
L+ Q +DL+ +++Q E + L R++ + E +L E+ + A +K LE
Sbjct: 219 MQALKGQFERDLQARDEQ---NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD 275
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
D + ++ R ++ + + +L Q+K+ + EDA DE+ A ++
Sbjct: 276 LK-DLELQADSAIKGR-EEAIKHVRKLQAQMKDFQRELEDARASRDEI---FATAKEN-- 328
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E + KS +A + +L+E+L + K ++ +E+
Sbjct: 329 --EKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 362
Score = 47.6 bits (108), Expect = 5e-05
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 6/206 (2%)
Query: 15 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 74
K D A T E + R +K E + + ++ A + L KN+L+Q DL
Sbjct: 27 KKKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 85
Query: 75 EKQLTATEAEVAALNRKVQQI-EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
+ + RK Q+ E+ S + + + EA++ + + + LE
Sbjct: 86 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEA 145
Query: 134 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 193
+ EE + TN++ +A + ED D+V + + +E E +++ ++ EL
Sbjct: 146 LEAKEEL--ERTNKMLKAEM--EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 201
Query: 194 EEELKVVGNSLKSLEVSEEKANQRVE 219
E+EL+ ++ LEV+ + + E
Sbjct: 202 EDELQATEDAKLRLEVNMQALKGQFE 227
Score = 47.2 bits (107), Expect = 7e-05
Identities = 36/202 (17%), Positives = 83/202 (41%), Gaps = 2/202 (0%)
Query: 19 MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQL 78
M+ E+ N++ +++++ + +EE + ++E + EEK
Sbjct: 6 MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAY 65
Query: 79 TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADENNRMCKVLENRAQQD 137
E L +++ + DL+ + ++K + Q A+E N K + R + +
Sbjct: 66 DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 125
Query: 138 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 197
E ++ T L AR L E + K +E+ R ++ E+E + ELE+
Sbjct: 126 AEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 184
Query: 198 KVVGNSLKSLEVSEEKANQRVE 219
+ + ++ ++ E+ ++
Sbjct: 185 RALETQMEEMKTQLEELEDELQ 206
Score = 46.0 bits (104), Expect = 2e-04
Identities = 36/178 (20%), Positives = 82/178 (46%), Gaps = 8/178 (4%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
++A++ K + + QQ + +K+ + LQ++L +DL+++ + Q
Sbjct: 37 VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL----DDLVVDLDNQRQL 92
Query: 68 NKDLEEKEKQLTATEAEVAALNRKV----QQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+LE+K+++ AE ++ K + E + + E ++ + + L EA ++ +E
Sbjct: 93 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEEL 152
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
R K+L+ + D + + E + + +E+ +L +EDEL+ ED
Sbjct: 153 ERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 210
Score = 45.2 bits (102), Expect = 3e-04
Identities = 64/280 (22%), Positives = 110/280 (39%), Gaps = 28/280 (10%)
Query: 16 DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKE 75
D + + + D RAE E LA+ E+ + K +LE+ NK L+ +
Sbjct: 104 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 163
Query: 76 KQLTATEAEVA-----------ALNRKVQQIEEDLEKSE-ERSGTAQQKL-LEAQQSADE 122
+ L +++ +V AL ++++++ LE+ E E T KL LE A
Sbjct: 164 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQA-L 222
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
+ + L+ R +Q+EE+ QL QL E ED RK + L A +
Sbjct: 223 KGQFERDLQARDEQNEEKRRQLQRQLHEYETELED--------ERK----QRALAAAAKK 270
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXX 242
GD K EL+ + + G V K ++++F
Sbjct: 271 KLEGDLKDLELQADSAIKGREEAIKHV--RKLQAQMKDFQRELEDARASRDEIFATAKEN 328
Query: 243 XKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
K K L+ ++ +L+++L + K E + ELA
Sbjct: 329 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELA 368
>BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated,
coiled-coil containing protein kinase 1 protein.
Length = 1354
Score = 70.1 bits (164), Expect = 8e-12
Identities = 53/234 (22%), Positives = 124/234 (52%), Gaps = 25/234 (10%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-------RELQKKLAQVE 54
++++K + ++ + N M D EQ+ R +N++ +K+ +E+ R L+ ++Q+E
Sbjct: 426 ESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQIE 485
Query: 55 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
++ +L ++++ + + E++ ++ E EV+ L ++ EDL+K + S A +KL
Sbjct: 486 KEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKNQL----EDLKKVSQNSQLANEKLS 541
Query: 115 EAQQSADENNRMCKVLENRA----------QQDEERMDQLTNQLKEARLLAEDADGKSDE 164
+ Q+ +E N + + + A + +++ L +L+E + E++ ++D+
Sbjct: 542 QLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDK 601
Query: 165 VSRKL-AFVEDE-LEVAEDRVKSGD--AKISELEEELKVVGNSLKSLEVSEEKA 214
+L A +E E + D GD A+I+ L+EE+K + ++L+ +E ++A
Sbjct: 602 DYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEA 655
Score = 42.3 bits (95), Expect = 0.002
Identities = 49/233 (21%), Positives = 104/233 (44%), Gaps = 20/233 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K ++ ++ E+ A D + E++ NL + +N +++ LQ++L Q + + K +
Sbjct: 641 LKHNLEKVEGERKEAQDMLNHSEKEKN--NLEID-LNYKLKSLQQRLEQEVNEHKVTKAR 697
Query: 64 LEQANKDLEEK--------EKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
L ++ +EE EK+L EA A NR V QIE+ + +QQKL
Sbjct: 698 LTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVV-QIEKQCSMLDVDLKQSQQKLE 756
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL----- 169
+ + K L + +Q+ + L N+LK A++ G ++ +++
Sbjct: 757 HLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLE 816
Query: 170 --AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+E EL + + + ++ EL+++L+ + ++ + +EE
Sbjct: 817 AKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEE 869
Score = 39.5 bits (88), Expect = 0.013
Identities = 45/200 (22%), Positives = 92/200 (46%), Gaps = 17/200 (8%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 65
KK+Q ++ EK+ + D E +A L + E+ EL + E ++N+ E
Sbjct: 876 KKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQ-----ESKKAASRNRQE 930
Query: 66 QANKD-----LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+KD LEE LT ++ L R+ +++ E ++K+EE +++ + ++A
Sbjct: 931 ITDKDHTVSRLEEANSMLTK---DIEILRRENEELTERMKKAEEEYKLEKEEEISNLKAA 987
Query: 121 DENN-RMCKVLENRA-QQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF-VEDELE 177
E N + L+ +A + E M++ ++ + +D K E +RKL + E E
Sbjct: 988 FEKNINTERTLKTQAVNKLAEIMNRKDFKIDRKKANTQDLRKKEKE-NRKLQLELNQERE 1046
Query: 178 VAEDRVKSGDAKISELEEEL 197
V ++++++ +L
Sbjct: 1047 KFNQMVVKHQKELNDMQAQL 1066
Score = 37.9 bits (84), Expect = 0.040
Identities = 36/184 (19%), Positives = 87/184 (47%), Gaps = 7/184 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D +K + MK E + ++ E + + ++RELQ +L + L K
Sbjct: 798 DNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYK 857
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++++ +++EEK ++ + + ++ + DL +++ S + LLE Q
Sbjct: 858 TQVKELKEEIEEKNRE-NLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYF-- 914
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEAR-LLAEDAD---GKSDEVSRKLAFVEDELE 177
E + K +R +Q+ D ++L+EA +L +D + +++E++ ++ E+E +
Sbjct: 915 ELTQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTERMKKAEEEYK 974
Query: 178 VAED 181
+ ++
Sbjct: 975 LEKE 978
Score = 33.5 bits (73), Expect = 0.86
Identities = 41/273 (15%), Positives = 111/273 (40%), Gaps = 6/273 (2%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M ++KK++ + ++ A ++ E+Q ++ ++ +++ L ++E+++
Sbjct: 713 MCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNL 772
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+LEQ + + +L E L +Q+++++ E + +L + +
Sbjct: 773 TLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQY 832
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
N + L+++ + ++ Q+KE L E+ + K+ E +K+ +++E E
Sbjct: 833 RGNEGQMRELQDQLEAEQYFSTLYKTQVKE---LKEEIEEKNRENLKKIQELQNEKETLA 889
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
++ + K + ++ L +KA R +
Sbjct: 890 TQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRNRQ---EITDKDHTVSRLEEANS 946
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADE 273
K ++ L++E + L + + ++ YK +E
Sbjct: 947 MLTKDIEILRRENEELTERMKKAEEEYKLEKEE 979
Score = 30.7 bits (66), Expect = 6.1
Identities = 32/171 (18%), Positives = 73/171 (42%), Gaps = 8/171 (4%)
Query: 119 SADEN-NRMCKVLENRAQQD-EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
SA+ N NR + Q+ ++ + +L QL L ++ + K + KL + EL
Sbjct: 408 SANPNDNRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKEL 467
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR---VEEFXXXXXXXXXXXX 233
+ ++ ++ ++ +S++E+E ++ + + + E+ N++ VE
Sbjct: 468 DEEGNQRRNLESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKNQLEDLK 527
Query: 234 XXXXXXXXXXKTVKKLQKEVDRLEDELGINKD---RYKSLADEMDSTFAEL 281
+ + +LQK+++ D L D R + EM + ++L
Sbjct: 528 KVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQL 578
>U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-coil
containing protein kinase p160ROCK protein.
Length = 1354
Score = 69.3 bits (162), Expect = 1e-11
Identities = 53/234 (22%), Positives = 124/234 (52%), Gaps = 25/234 (10%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-------RELQKKLAQVE 54
++++K + ++ + N M D EQ+ R +N++ +K+ +E+ R L+ ++Q+E
Sbjct: 426 ESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQIE 485
Query: 55 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
++ +L ++++ + + E++ ++ E EV+ L ++ EDL+K + S A +KL
Sbjct: 486 KEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQL----EDLKKVSQNSQLANEKLS 541
Query: 115 EAQQSADENNRMCKVLENRA----------QQDEERMDQLTNQLKEARLLAEDADGKSDE 164
+ Q+ +E N + + + A + +++ L +L+E + E++ ++D+
Sbjct: 542 QLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDK 601
Query: 165 VSRKL-AFVEDE-LEVAEDRVKSGD--AKISELEEELKVVGNSLKSLEVSEEKA 214
+L A +E E + D GD A+I+ L+EE+K + ++L+ +E ++A
Sbjct: 602 DYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEA 655
Score = 42.3 bits (95), Expect = 0.002
Identities = 49/233 (21%), Positives = 104/233 (44%), Gaps = 20/233 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K ++ ++ E+ A D + E++ NL + +N +++ LQ++L Q + + K +
Sbjct: 641 LKHNLEKVEGERKEAQDMLNHSEKEKN--NLEID-LNYKLKSLQQRLEQEVNEHKVTKAR 697
Query: 64 LEQANKDLEEK--------EKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
L ++ +EE EK+L EA A NR V QIE+ + +QQKL
Sbjct: 698 LTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVV-QIEKQCSMLDVDLKQSQQKLE 756
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL----- 169
+ + K L + +Q+ + L N+LK A++ G ++ +++
Sbjct: 757 HLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLE 816
Query: 170 --AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+E EL + + + ++ EL+++L+ + ++ + +EE
Sbjct: 817 AKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEE 869
Score = 39.9 bits (89), Expect = 0.010
Identities = 45/200 (22%), Positives = 92/200 (46%), Gaps = 17/200 (8%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 65
KK+Q ++ EK+ + D E +A L + E+ EL + E ++N+ E
Sbjct: 876 KKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQ-----ESKKAASRNRQE 930
Query: 66 QANKD-----LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+KD LEE LT ++ L R+ +++ E ++K+EE +++ + ++A
Sbjct: 931 ITDKDHTVSRLEEANSMLTK---DIEILRRENEELTEKMKKAEEEYKLEKEEEISNLKAA 987
Query: 121 DENN-RMCKVLENRA-QQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF-VEDELE 177
E N + L+ +A + E M++ ++ + +D K E +RKL + E E
Sbjct: 988 FEKNINTERTLKTQAVNKLAEIMNRKDFKIDRKKANTQDLRKKEKE-NRKLQLELNQERE 1046
Query: 178 VAEDRVKSGDAKISELEEEL 197
V ++++++ +L
Sbjct: 1047 KFNQMVVKHQKELNDMQAQL 1066
Score = 39.1 bits (87), Expect = 0.017
Identities = 37/184 (20%), Positives = 87/184 (47%), Gaps = 7/184 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D +K + MK E + ++ E + + ++RELQ +L + L K
Sbjct: 798 DNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYK 857
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++++ +++EEK ++ + + ++ + DL +++ S + LLE Q
Sbjct: 858 TQVKELKEEIEEKNRE-NLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYF-- 914
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEAR-LLAEDAD---GKSDEVSRKLAFVEDELE 177
E + K +R +Q+ D ++L+EA +L +D + +++E++ K+ E+E +
Sbjct: 915 ELTQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYK 974
Query: 178 VAED 181
+ ++
Sbjct: 975 LEKE 978
Score = 33.9 bits (74), Expect = 0.65
Identities = 41/273 (15%), Positives = 112/273 (41%), Gaps = 6/273 (2%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M ++KK++ + ++ A ++ E+Q ++ ++ +++ L ++E+++
Sbjct: 713 MCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNL 772
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+LEQ + + +L E L +Q+++++ E + +L + +
Sbjct: 773 TLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQY 832
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
N + L+++ + ++ Q+KE L E+ + K+ E +K+ +++E E
Sbjct: 833 RGNEGQMRELQDQLEAEQYFSTLYKTQVKE---LKEEIEEKNRENLKKIQELQNEKETLA 889
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
++ + K + ++ L +KA R +
Sbjct: 890 TQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRNRQ---EITDKDHTVSRLEEANS 946
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADE 273
K ++ L++E + L +++ ++ YK +E
Sbjct: 947 MLTKDIEILRRENEELTEKMKKAEEEYKLEKEE 979
Score = 30.7 bits (66), Expect = 6.1
Identities = 32/171 (18%), Positives = 73/171 (42%), Gaps = 8/171 (4%)
Query: 119 SADEN-NRMCKVLENRAQQD-EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
SA+ N NR + Q+ ++ + +L QL L ++ + K + KL + EL
Sbjct: 408 SANPNDNRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKEL 467
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR---VEEFXXXXXXXXXXXX 233
+ ++ ++ ++ +S++E+E ++ + + + E+ N++ VE
Sbjct: 468 DEEGNQRRNLESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLK 527
Query: 234 XXXXXXXXXXKTVKKLQKEVDRLEDELGINKD---RYKSLADEMDSTFAEL 281
+ + +LQK+++ D L D R + EM + ++L
Sbjct: 528 KVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQL 578
>AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated,
coiled-coil containing protein kinase 1 variant protein.
Length = 705
Score = 69.3 bits (162), Expect = 1e-11
Identities = 53/234 (22%), Positives = 124/234 (52%), Gaps = 25/234 (10%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-------RELQKKLAQVE 54
++++K + ++ + N M D EQ+ R +N++ +K+ +E+ R L+ ++Q+E
Sbjct: 104 ESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQIE 163
Query: 55 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
++ +L ++++ + + E++ ++ E EV+ L ++ EDL+K + S A +KL
Sbjct: 164 KEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQL----EDLKKVSQNSQLANEKLS 219
Query: 115 EAQQSADENNRMCKVLENRA----------QQDEERMDQLTNQLKEARLLAEDADGKSDE 164
+ Q+ +E N + + + A + +++ L +L+E + E++ ++D+
Sbjct: 220 QLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDK 279
Query: 165 VSRKL-AFVEDE-LEVAEDRVKSGD--AKISELEEELKVVGNSLKSLEVSEEKA 214
+L A +E E + D GD A+I+ L+EE+K + ++L+ +E ++A
Sbjct: 280 DYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEA 333
Score = 42.3 bits (95), Expect = 0.002
Identities = 49/233 (21%), Positives = 104/233 (44%), Gaps = 20/233 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K ++ ++ E+ A D + E++ NL + +N +++ LQ++L Q + + K +
Sbjct: 319 LKHNLEKVEGERKEAQDMLNHSEKEKN--NLEID-LNYKLKSLQQRLEQEVNEHKVTKAR 375
Query: 64 LEQANKDLEEK--------EKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
L ++ +EE EK+L EA A NR V QIE+ + +QQKL
Sbjct: 376 LTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVV-QIEKQCSMLDVDLKQSQQKLE 434
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL----- 169
+ + K L + +Q+ + L N+LK A++ G ++ +++
Sbjct: 435 HLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLE 494
Query: 170 --AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+E EL + + + ++ EL+++L+ + ++ + +EE
Sbjct: 495 AKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEE 547
Score = 39.1 bits (87), Expect = 0.017
Identities = 37/184 (20%), Positives = 87/184 (47%), Gaps = 7/184 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D +K + MK E + ++ E + + ++RELQ +L + L K
Sbjct: 476 DNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYK 535
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++++ +++EEK ++ + + ++ + DL +++ S + LLE Q
Sbjct: 536 TQVKELKEEIEEKNRE-NLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYF-- 592
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEAR-LLAEDAD---GKSDEVSRKLAFVEDELE 177
E + K +R +Q+ D ++L+EA +L +D + +++E++ K+ E+E +
Sbjct: 593 ELTQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYK 652
Query: 178 VAED 181
+ ++
Sbjct: 653 LEKE 656
Score = 37.9 bits (84), Expect = 0.040
Identities = 31/124 (25%), Positives = 59/124 (47%), Gaps = 13/124 (10%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 65
KK+Q ++ EK+ + D E +A L + E+ EL + E ++N+ E
Sbjct: 554 KKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQ-----ESKKAASRNRQE 608
Query: 66 QANKD-----LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+KD LEE LT ++ L R+ +++ E ++K+EE +++ + ++A
Sbjct: 609 ITDKDHTVSRLEEANSMLTK---DIEILRRENEELTEKMKKAEEEYKLEKEEEISNLKAA 665
Query: 121 DENN 124
E N
Sbjct: 666 FEKN 669
Score = 33.9 bits (74), Expect = 0.65
Identities = 41/273 (15%), Positives = 112/273 (41%), Gaps = 6/273 (2%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M ++KK++ + ++ A ++ E+Q ++ ++ +++ L ++E+++
Sbjct: 391 MCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNL 450
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+LEQ + + +L E L +Q+++++ E + +L + +
Sbjct: 451 TLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQY 510
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
N + L+++ + ++ Q+KE L E+ + K+ E +K+ +++E E
Sbjct: 511 RGNEGQMRELQDQLEAEQYFSTLYKTQVKE---LKEEIEEKNRENLKKIQELQNEKETLA 567
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
++ + K + ++ L +KA R +
Sbjct: 568 TQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRNRQ---EITDKDHTVSRLEEANS 624
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADE 273
K ++ L++E + L +++ ++ YK +E
Sbjct: 625 MLTKDIEILRRENEELTEKMKKAEEEYKLEKEE 657
Score = 30.7 bits (66), Expect = 6.1
Identities = 32/171 (18%), Positives = 73/171 (42%), Gaps = 8/171 (4%)
Query: 119 SADEN-NRMCKVLENRAQQD-EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
SA+ N NR + Q+ ++ + +L QL L ++ + K + KL + EL
Sbjct: 86 SANPNDNRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKEL 145
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR---VEEFXXXXXXXXXXXX 233
+ ++ ++ ++ +S++E+E ++ + + + E+ N++ VE
Sbjct: 146 DEEGNQRRNLESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLK 205
Query: 234 XXXXXXXXXXKTVKKLQKEVDRLEDELGINKD---RYKSLADEMDSTFAEL 281
+ + +LQK+++ D L D R + EM + ++L
Sbjct: 206 KVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQL 256
>M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein.
Length = 1976
Score = 68.1 bits (159), Expect = 3e-11
Identities = 55/255 (21%), Positives = 112/255 (43%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ R L K++ ++E +L + + A ++ E L EA++
Sbjct: 1575 QFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIE 1634
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
A N+ ++ + L K + + Q++L EA+ S DE K E + + E + QL
Sbjct: 1635 AANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQE 1694
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
+L + A+ + DE++ ++ D + +A+I++LEEEL+ ++++
Sbjct: 1695 ELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMEL 1754
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
L K +V+ + K+L+ ++ LE G K +
Sbjct: 1755 LNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELE---GAVKSK 1811
Query: 267 YKSLADEMDSTFAEL 281
+K+ +++ +L
Sbjct: 1812 FKATISALEAKIGQL 1826
Score = 60.5 bits (140), Expect = 7e-09
Identities = 59/298 (19%), Positives = 131/298 (43%), Gaps = 17/298 (5%)
Query: 2 DAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
+A +K+ +A+ L + + A++ + E+Q + E + ++ K + ++E+
Sbjct: 1477 EAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRA 1536
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGTAQQKLLE 115
+ ++E+ LEE E +L ATE L +Q Q E DL+ +E++ ++ L++
Sbjct: 1537 LEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIK 1596
Query: 116 AQQSAD---ENNRMCKVLENRAQQDEE-RMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
+ + E+ R + L +++ E + L Q++ A ++ + ++ ++
Sbjct: 1597 QVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKD 1656
Query: 172 VEDELEVAE---DRV----KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXX 224
+ ELE A D + K + K+ LE E+ + L S E + A Q +E
Sbjct: 1657 YQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADE 1716
Query: 225 XXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
+ +L++E++ + + + DR++ ++D+ AELA
Sbjct: 1717 ITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELA 1774
Score = 56.8 bits (131), Expect = 8e-08
Identities = 59/260 (22%), Positives = 108/260 (41%), Gaps = 15/260 (5%)
Query: 22 ADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK----EKQ 77
A + E Q +D ++ + L ++ Q+EE+ KN L++ ++ EE EKQ
Sbjct: 1310 AASLESQLQDTQELLQEETRQKLNLSSRIRQLEEE----KNSLQEQQEEEEEARKNLEKQ 1365
Query: 78 LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQD 137
+ A ++++A +KV +E EE + Q +E LE +
Sbjct: 1366 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL 1425
Query: 138 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 197
++ +D LT L R +A + + K + + LA E++ A + A+ E+E
Sbjct: 1426 QQELDDLTVDLDHQRQVASNLEKKQKKFDQLLA--EEKSISARYAEERDRAEAEAREKET 1483
Query: 198 KVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLE 257
K + SL + E+A + EEF K V +L+K LE
Sbjct: 1484 KAL-----SLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALE 1538
Query: 258 DELGINKDRYKSLADEMDST 277
++ + + + L DE+ +T
Sbjct: 1539 QQVEEMRTQLEELEDELQAT 1558
Score = 54.4 bits (125), Expect = 4e-07
Identities = 38/200 (19%), Positives = 96/200 (48%), Gaps = 9/200 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ ++ ++ E + + + R L+ + +N E+ ++ AQ ++ + +
Sbjct: 1734 LEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAA-ERSAAQKSDNA---RQQ 1789
Query: 64 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
LE+ NK+L+ K ++L +A ++AL K+ Q+EE LE+ + A + + ++
Sbjct: 1790 LERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEK 1849
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
E + A Q +E+M++ ++K+ + E+A+ ++ + ++ EL+
Sbjct: 1850 KLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDD 1909
Query: 179 AEDRVKSGDAKISELEEELK 198
A + + ++S L+ L+
Sbjct: 1910 ATEANEGLSREVSTLKNRLR 1929
Score = 53.6 bits (123), Expect = 8e-07
Identities = 58/285 (20%), Positives = 121/285 (42%), Gaps = 14/285 (4%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D K++ A+ +K +D D E Q AN ++V +++R+LQ ++ + +L +
Sbjct: 1607 DERKQRALAVASKKKMEIDLKDL-EAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEAR 1665
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ +E EK+L + EAE+ Q++E+L SE A+Q+ E
Sbjct: 1666 ASRDEIFAQSKESEKKLKSLEAEIL-------QLQEELASSERARRHAEQERDELADEIT 1718
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
+ L + ++ E R+ QL +L+E + E + + + + ++ + EL
Sbjct: 1719 NSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERS 1778
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+ D +LE + K + L+ LE + K +
Sbjct: 1779 AAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERA 1838
Query: 241 XXXKTVKKLQKEVD----RLEDELGINKDRYKSLADEMDSTFAEL 281
K V++ +K++ ++EDE + D+YK ++ ++ +L
Sbjct: 1839 AANKLVRRTEKKLKEIFMQVEDERR-HADQYKEQMEKANARMKQL 1882
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/224 (20%), Positives = 99/224 (44%), Gaps = 8/224 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++++ + + + +A + D + ++ + +E R L+ ++AQ+EE+L ++
Sbjct: 1692 LQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSN 1751
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+E N + Q+ AE+AA Q+ + ++ E ++ + KL E + +
Sbjct: 1752 MELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSK 1811
Query: 124 NRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV-------SRKLAFVEDE 175
+ LE + Q EE+++Q + A L + K E+ R +++
Sbjct: 1812 FKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQ 1871
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+E A R+K ++ E EEE S + L+ + A + E
Sbjct: 1872 MEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANE 1915
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/217 (20%), Positives = 97/217 (44%), Gaps = 7/217 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A++ ++ K + D+ + ++ E+ + AE +++ + E K LA + L KN
Sbjct: 1368 ALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE--KALAY--DKLEKTKN 1423
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L+Q +L++ L + L +K ++ ++ L + + S ++ A+ A E
Sbjct: 1424 RLQQ---ELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEARE 1480
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
L ++ E ++ Q K+ R ED D+V + + +E E +
Sbjct: 1481 KETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQ 1540
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
V+ ++ ELE+EL+ ++ LEV+ + + E
Sbjct: 1541 VEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFE 1577
Score = 50.4 bits (115), Expect = 7e-06
Identities = 49/278 (17%), Positives = 116/278 (41%), Gaps = 8/278 (2%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
K++ + +L+K ++ E Q +D R EE+ E ++ + + +L NK L
Sbjct: 1171 KREQEVAELKKA-LEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGL 1229
Query: 65 EQANKDLEEKEKQLTATEAEV----AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
E NK+L + K L +AE L+ +VQ++ + + + +K + Q
Sbjct: 1230 ETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNEL 1289
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
D + + + E + + + L +QL++ + L ++ + +S ++ +E+E +
Sbjct: 1290 DNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQ 1349
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
++ + + LE+++ + + L + + +E
Sbjct: 1350 EQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLE 1409
Query: 241 XXXKTVKKLQKEVDRLE---DELGINKDRYKSLADEMD 275
KL+K +RL+ D+L ++ D + +A ++
Sbjct: 1410 EKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLE 1447
Score = 49.6 bits (113), Expect = 1e-05
Identities = 48/219 (21%), Positives = 106/219 (48%), Gaps = 18/219 (8%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
KKKMQA + + +D+ + Q+ L+ EKV E K+ ++EE+++L +++
Sbjct: 945 KKKMQAHIQDLEEQLDEEEGARQK-----LQLEKVTAEA-----KIKKMEEEILLLEDQN 994
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
+ K+ + E ++ +++A K + + + K E +++L + +++ E
Sbjct: 995 SKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELE 1054
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARL-LAEDADGKSDEVSRKLAFVEDEL---EVAE 180
+ + L+ ++++ +L Q+ E +L LA+ K +E+ LA +DE A
Sbjct: 1055 KAKRKLDGETTDLQDQIAELQAQIDELKLQLAK----KEEELQGALARGDDETLHKNNAL 1110
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
V+ A+I+EL+E+ + S E + ++ +E
Sbjct: 1111 KVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELE 1149
Score = 48.4 bits (110), Expect = 3e-05
Identities = 69/282 (24%), Positives = 129/282 (45%), Gaps = 20/282 (7%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQA-RDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +K K + K+E + +++ + QQ + N+ AE++ E EL + ++ L
Sbjct: 860 ELLKVKEKQTKVEGE--LEEMERKHQQLLEEKNILAEQLQAET-ELFAEAEEMRARLAAK 916
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K +LE+ DLE + ++ + +K+Q +DLE+ + A+QKL + +A
Sbjct: 917 KQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTA 976
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE-VA 179
+ K +E E DQ + +KE +L+ ED + E S +LA E++ + +A
Sbjct: 977 EAK---IKKMEEEILLLE---DQNSKFIKEKKLM-ED---RIAECSSQLAEEEEKAKNLA 1026
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
+ R K + IS+LEE LK + + LE ++ K + E
Sbjct: 1027 KIRNKQ-EVMISDLEERLKKEEKTRQELEKAKRKLD---GETTDLQDQIAELQAQIDELK 1082
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K ++LQ + R +DE ++K+ + E+ + AEL
Sbjct: 1083 LQLAKKEEELQGALARGDDET-LHKNNALKVVRELQAQIAEL 1123
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/161 (23%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Query: 38 KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 97
K + L+ K+ Q+EE L + ANK + EK+L +V R Q +E
Sbjct: 1811 KFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKE 1870
Query: 98 DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR---AQQDEERMDQLTNQLKEARLL 154
+EK+ R +++L EA++ A N + L+ A + E + + + LK
Sbjct: 1871 QMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1930
Query: 155 AEDADGKSDEVSRKLAFVED-ELEVAEDRVKSGDAKISELE 194
S R+ +E LE+++D +S + ++E +
Sbjct: 1931 GGPISFSSSRSGRRQLHLEGASLELSDDDTESKTSDVNETQ 1971
Score = 48.0 bits (109), Expect = 4e-05
Identities = 56/265 (21%), Positives = 114/265 (43%), Gaps = 27/265 (10%)
Query: 26 EQQARDANL-----RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 80
E QA+D L + KV E+ E+++K Q+ E+ + +L+ + E E+
Sbjct: 853 ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEM--- 909
Query: 81 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 140
A +AA +++++I DLE E Q L +N + K ++ Q EE+
Sbjct: 910 -RARLAAKKQELEEILHDLESRVEEEEERNQIL--------QNEK--KKMQAHIQDLEEQ 958
Query: 141 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED-------ELEVAEDRVKSGDAKISEL 193
+D+ ++ +L A+ K ++ ++ +ED E ++ EDR+ ++++E
Sbjct: 959 LDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEE 1018
Query: 194 EEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEV 253
EE+ K + EV +R+++ + +LQ ++
Sbjct: 1019 EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQI 1078
Query: 254 DRLEDELGINKDRYK-SLADEMDST 277
D L+ +L ++ + +LA D T
Sbjct: 1079 DELKLQLAKKEEELQGALARGDDET 1103
Score = 46.8 bits (106), Expect = 9e-05
Identities = 50/248 (20%), Positives = 103/248 (41%), Gaps = 14/248 (5%)
Query: 42 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 101
+V +++L +E+L+ K K + +LEE E++ E L ++Q E +
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAE 905
Query: 102 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
+EE K E ++ + LE+R +++EER L N+ K+ + +D + +
Sbjct: 906 AEEMRARLAAKKQELEEILHD-------LESRVEEEEERNQILQNEKKKMQAHIQDLEEQ 958
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE-------ELKVVGNSLKSLEVSEEKA 214
DE ++ E AE ++K + +I LE+ E K++ + + +
Sbjct: 959 LDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEE 1018
Query: 215 NQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
++ + KT ++L+K +L+ E +D+ L ++
Sbjct: 1019 EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQI 1078
Query: 275 DSTFAELA 282
D +LA
Sbjct: 1079 DELKLQLA 1086
Score = 46.4 bits (105), Expect = 1e-04
Identities = 49/249 (19%), Positives = 98/249 (39%), Gaps = 10/249 (4%)
Query: 13 LEKDNAMDKADTCEQQARDA--NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKD 70
L K+NA+ + Q + + +EK + E QK+ + E+L K +LE
Sbjct: 1104 LHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKR--DLSEELEALKTELEDTLDT 1161
Query: 71 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
+++ T E EVA L + +EE+ + E + +Q+ A + E K
Sbjct: 1162 TAAQQELRTKREQEVAELKK---ALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRF 1218
Query: 131 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 190
+ +++++ ++ +L + + +S+ +KL EL +V GD
Sbjct: 1219 KANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHA---KVSEGDRLR 1275
Query: 191 SELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQ 250
EL E+ + N L ++ E+A ++ +F + L
Sbjct: 1276 VELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLS 1335
Query: 251 KEVDRLEDE 259
+ +LE+E
Sbjct: 1336 SRIRQLEEE 1344
Score = 45.2 bits (102), Expect = 3e-04
Identities = 53/288 (18%), Positives = 115/288 (39%), Gaps = 11/288 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEK--VNEEVRELQKK---LAQVEE 55
+D ++ A LEK E+++ A E+ E RE + K LA+ E
Sbjct: 1434 VDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALE 1493
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ + K + E+ NK L + L +++ +V ++++ + LE+ E T ++L +
Sbjct: 1494 EALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELED 1553
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE--ARLLAEDADGKSDEVSRKLAFVE 173
Q+ ++ +V + ER Q ++ E RLL + E+ +L
Sbjct: 1554 ELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQV----RELEAELEDER 1609
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXX 233
+ +A K + + +LE +++ + + K +++++
Sbjct: 1610 KQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRD 1669
Query: 234 XXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K +K L+ E+ +L++EL ++ + E D E+
Sbjct: 1670 EIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEI 1717
Score = 42.7 bits (96), Expect = 0.001
Identities = 42/200 (21%), Positives = 92/200 (46%), Gaps = 17/200 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ-------VEED 56
++K Q ++ + + +Q ++ + +K++ +V+EL K+++ + E
Sbjct: 1222 LEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEK 1281
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+N+L+ + LEE EK+ + A+L ++Q +E L++ + ++
Sbjct: 1282 ASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRI--- 1338
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
+Q +E N L+ + +++EE L Q+ L ++ AD K +V L +E
Sbjct: 1339 RQLEEEKNS----LQEQQEEEEEARKNLEKQV--LALQSQLADTKK-KVDDDLGTIESLE 1391
Query: 177 EVAEDRVKSGDAKISELEEE 196
E + +K +A LEE+
Sbjct: 1392 EAKKKLLKDAEALSQRLEEK 1411
Score = 40.3 bits (90), Expect = 0.007
Identities = 36/204 (17%), Positives = 77/204 (37%), Gaps = 3/204 (1%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 73
EK D+ C Q + +A+ + + + + ++ +EE L + ++ K +
Sbjct: 1000 EKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRK 1059
Query: 74 KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
+ + T + ++A L ++ +++ L K EE Q L N KV+
Sbjct: 1060 LDGETTDLQDQIAELQAQIDELKLQLAKKEEE---LQGALARGDDETLHKNNALKVVREL 1116
Query: 134 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 193
Q E + ++ + S+E+ +ED L+ + + + E+
Sbjct: 1117 QAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEV 1176
Query: 194 EEELKVVGNSLKSLEVSEEKANQR 217
E K + K+ E + QR
Sbjct: 1177 AELKKALEEETKNHEAQIQDMRQR 1200
Score = 38.7 bits (86), Expect = 0.023
Identities = 43/259 (16%), Positives = 104/259 (40%), Gaps = 10/259 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+ ++ ++ A K E + + ++ ++ + N + + E +++Q + +EE L +
Sbjct: 907 EEMRARLAAKKQELEEILHDLESRVEEEEERN---QILQNEKKKMQAHIQDLEEQLDEEE 963
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ + E ++ E E+ L + + ++ + E+R +L E ++ A
Sbjct: 964 GARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAK 1023
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
++ E EER+ + +E DG++ ++ ++A EL+ D
Sbjct: 1024 NLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIA----ELQAQID 1079
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXX 241
+K ++++ EEEL+ + + A + V E
Sbjct: 1080 ELK---LQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNK 1136
Query: 242 XXKTVKKLQKEVDRLEDEL 260
K + L +E++ L+ EL
Sbjct: 1137 AEKQKRDLSEELEALKTEL 1155
Score = 36.7 bits (81), Expect = 0.092
Identities = 29/134 (21%), Positives = 67/134 (50%), Gaps = 10/134 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A+K K +A + + + + EQ ++A RA N+ VR +KKL ++
Sbjct: 1807 AVKSKFKATISALEAKIGQLE--EQLEQEAKERAA-ANKLVRRTEKKLKEIFM------- 1856
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
++E + ++ ++Q+ A + L R++++ EE+ ++ Q++L +A ++ +
Sbjct: 1857 QVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEG 1916
Query: 123 NNRMCKVLENRAQQ 136
+R L+NR ++
Sbjct: 1917 LSREVSTLKNRLRR 1930
>BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 68.1 bits (159), Expect = 3e-11
Identities = 55/255 (21%), Positives = 112/255 (43%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ R L K++ ++E +L + + A ++ E L EA++
Sbjct: 1575 QFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIE 1634
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
A N+ ++ + L K + + Q++L EA+ S DE K E + + E + QL
Sbjct: 1635 AANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQE 1694
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
+L + A+ + DE++ ++ D + +A+I++LEEEL+ ++++
Sbjct: 1695 ELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMEL 1754
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
L K +V+ + K+L+ ++ LE G K +
Sbjct: 1755 LNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELE---GAVKSK 1811
Query: 267 YKSLADEMDSTFAEL 281
+K+ +++ +L
Sbjct: 1812 FKATISALEAKIGQL 1826
Score = 60.5 bits (140), Expect = 7e-09
Identities = 59/298 (19%), Positives = 131/298 (43%), Gaps = 17/298 (5%)
Query: 2 DAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
+A +K+ +A+ L + + A++ + E+Q + E + ++ K + ++E+
Sbjct: 1477 EAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRA 1536
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGTAQQKLLE 115
+ ++E+ LEE E +L ATE L +Q Q E DL+ +E++ ++ L++
Sbjct: 1537 LEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIK 1596
Query: 116 AQQSAD---ENNRMCKVLENRAQQDEE-RMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
+ + E+ R + L +++ E + L Q++ A ++ + ++ ++
Sbjct: 1597 QVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKD 1656
Query: 172 VEDELEVAE---DRV----KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXX 224
+ ELE A D + K + K+ LE E+ + L S E + A Q +E
Sbjct: 1657 YQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADE 1716
Query: 225 XXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
+ +L++E++ + + + DR++ ++D+ AELA
Sbjct: 1717 ITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELA 1774
Score = 56.8 bits (131), Expect = 8e-08
Identities = 59/260 (22%), Positives = 108/260 (41%), Gaps = 15/260 (5%)
Query: 22 ADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK----EKQ 77
A + E Q +D ++ + L ++ Q+EE+ KN L++ ++ EE EKQ
Sbjct: 1310 AASLESQLQDTQELLQEETRQKLNLSSRIRQLEEE----KNSLQEQQEEEEEARKNLEKQ 1365
Query: 78 LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQD 137
+ A ++++A +KV +E EE + Q +E LE +
Sbjct: 1366 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL 1425
Query: 138 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 197
++ +D LT L R +A + + K + + LA E++ A + A+ E+E
Sbjct: 1426 QQELDDLTVDLDHQRQVASNLEKKQKKFDQLLA--EEKSISARYAEERDRAEAEAREKET 1483
Query: 198 KVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLE 257
K + SL + E+A + EEF K V +L+K LE
Sbjct: 1484 KAL-----SLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALE 1538
Query: 258 DELGINKDRYKSLADEMDST 277
++ + + + L DE+ +T
Sbjct: 1539 QQVEEMRTQLEELEDELQAT 1558
Score = 54.4 bits (125), Expect = 4e-07
Identities = 38/200 (19%), Positives = 96/200 (48%), Gaps = 9/200 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ ++ ++ E + + + R L+ + +N E+ ++ AQ ++ + +
Sbjct: 1734 LEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAA-ERSAAQKSDNA---RQQ 1789
Query: 64 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
LE+ NK+L+ K ++L +A ++AL K+ Q+EE LE+ + A + + ++
Sbjct: 1790 LERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEK 1849
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
E + A Q +E+M++ ++K+ + E+A+ ++ + ++ EL+
Sbjct: 1850 KLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDD 1909
Query: 179 AEDRVKSGDAKISELEEELK 198
A + + ++S L+ L+
Sbjct: 1910 ATEANEGLSREVSTLKNRLR 1929
Score = 53.6 bits (123), Expect = 8e-07
Identities = 58/285 (20%), Positives = 121/285 (42%), Gaps = 14/285 (4%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D K++ A+ +K +D D E Q AN ++V +++R+LQ ++ + +L +
Sbjct: 1607 DERKQRALAVASKKKMEIDLKDL-EAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEAR 1665
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ +E EK+L + EAE+ Q++E+L SE A+Q+ E
Sbjct: 1666 ASRDEIFAQSKESEKKLKSLEAEIL-------QLQEELASSERARRHAEQERDELADEIT 1718
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
+ L + ++ E R+ QL +L+E + E + + + + ++ + EL
Sbjct: 1719 NSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERS 1778
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+ D +LE + K + L+ LE + K +
Sbjct: 1779 AAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERA 1838
Query: 241 XXXKTVKKLQKEVD----RLEDELGINKDRYKSLADEMDSTFAEL 281
K V++ +K++ ++EDE + D+YK ++ ++ +L
Sbjct: 1839 AANKLVRRTEKKLKEIFMQVEDERR-HADQYKEQMEKANARMKQL 1882
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/224 (20%), Positives = 99/224 (44%), Gaps = 8/224 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++++ + + + +A + D + ++ + +E R L+ ++AQ+EE+L ++
Sbjct: 1692 LQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSN 1751
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+E N + Q+ AE+AA Q+ + ++ E ++ + KL E + +
Sbjct: 1752 MELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSK 1811
Query: 124 NRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV-------SRKLAFVEDE 175
+ LE + Q EE+++Q + A L + K E+ R +++
Sbjct: 1812 FKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQ 1871
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+E A R+K ++ E EEE S + L+ + A + E
Sbjct: 1872 MEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANE 1915
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/217 (20%), Positives = 97/217 (44%), Gaps = 7/217 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A++ ++ K + D+ + ++ E+ + AE +++ + E K LA + L KN
Sbjct: 1368 ALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE--KALAY--DKLEKTKN 1423
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L+Q +L++ L + L +K ++ ++ L + + S ++ A+ A E
Sbjct: 1424 RLQQ---ELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEARE 1480
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
L ++ E ++ Q K+ R ED D+V + + +E E +
Sbjct: 1481 KETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQ 1540
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
V+ ++ ELE+EL+ ++ LEV+ + + E
Sbjct: 1541 VEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFE 1577
Score = 50.4 bits (115), Expect = 7e-06
Identities = 49/278 (17%), Positives = 116/278 (41%), Gaps = 8/278 (2%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
K++ + +L+K ++ E Q +D R EE+ E ++ + + +L NK L
Sbjct: 1171 KREQEVAELKKA-LEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGL 1229
Query: 65 EQANKDLEEKEKQLTATEAEV----AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
E NK+L + K L +AE L+ +VQ++ + + + +K + Q
Sbjct: 1230 ETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNEL 1289
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
D + + + E + + + L +QL++ + L ++ + +S ++ +E+E +
Sbjct: 1290 DNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQ 1349
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
++ + + LE+++ + + L + + +E
Sbjct: 1350 EQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLE 1409
Query: 241 XXXKTVKKLQKEVDRLE---DELGINKDRYKSLADEMD 275
KL+K +RL+ D+L ++ D + +A ++
Sbjct: 1410 EKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLE 1447
Score = 49.6 bits (113), Expect = 1e-05
Identities = 48/219 (21%), Positives = 106/219 (48%), Gaps = 18/219 (8%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
KKKMQA + + +D+ + Q+ L+ EKV E K+ ++EE+++L +++
Sbjct: 945 KKKMQAHIQDLEEQLDEEEGARQK-----LQLEKVTAEA-----KIKKMEEEILLLEDQN 994
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
+ K+ + E ++ +++A K + + + K E +++L + +++ E
Sbjct: 995 SKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELE 1054
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARL-LAEDADGKSDEVSRKLAFVEDEL---EVAE 180
+ + L+ ++++ +L Q+ E +L LA+ K +E+ LA +DE A
Sbjct: 1055 KAKRKLDGETTDLQDQIAELQAQIDELKLQLAK----KEEELQGALARGDDETLHKNNAL 1110
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
V+ A+I+EL+E+ + S E + ++ +E
Sbjct: 1111 KVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELE 1149
Score = 48.4 bits (110), Expect = 3e-05
Identities = 69/282 (24%), Positives = 129/282 (45%), Gaps = 20/282 (7%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQA-RDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +K K + K+E + +++ + QQ + N+ AE++ E EL + ++ L
Sbjct: 860 ELLKVKEKQTKVEGE--LEEMERKHQQLLEEKNILAEQLQAET-ELFAEAEEMRARLAAK 916
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K +LE+ DLE + ++ + +K+Q +DLE+ + A+QKL + +A
Sbjct: 917 KQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTA 976
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE-VA 179
+ K +E E DQ + +KE +L+ ED + E S +LA E++ + +A
Sbjct: 977 EAK---IKKMEEEILLLE---DQNSKFIKEKKLM-ED---RIAECSSQLAEEEEKAKNLA 1026
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
+ R K + IS+LEE LK + + LE ++ K + E
Sbjct: 1027 KIRNKQ-EVMISDLEERLKKEEKTRQELEKAKRKLD---GETTDLQDQIAELQAQIDELK 1082
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K ++LQ + R +DE ++K+ + E+ + AEL
Sbjct: 1083 LQLAKKEEELQGALARGDDET-LHKNNALKVVRELQAQIAEL 1123
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/161 (23%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Query: 38 KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 97
K + L+ K+ Q+EE L + ANK + EK+L +V R Q +E
Sbjct: 1811 KFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKE 1870
Query: 98 DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR---AQQDEERMDQLTNQLKEARLL 154
+EK+ R +++L EA++ A N + L+ A + E + + + LK
Sbjct: 1871 QMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1930
Query: 155 AEDADGKSDEVSRKLAFVED-ELEVAEDRVKSGDAKISELE 194
S R+ +E LE+++D +S + ++E +
Sbjct: 1931 GGPISFSSSRSGRRQLHLEGASLELSDDDTESKTSDVNETQ 1971
Score = 48.0 bits (109), Expect = 4e-05
Identities = 56/265 (21%), Positives = 114/265 (43%), Gaps = 27/265 (10%)
Query: 26 EQQARDANL-----RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 80
E QA+D L + KV E+ E+++K Q+ E+ + +L+ + E E+
Sbjct: 853 ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEM--- 909
Query: 81 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 140
A +AA +++++I DLE E Q L +N + K ++ Q EE+
Sbjct: 910 -RARLAAKKQELEEILHDLESRVEEEEERNQIL--------QNEK--KKMQAHIQDLEEQ 958
Query: 141 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED-------ELEVAEDRVKSGDAKISEL 193
+D+ ++ +L A+ K ++ ++ +ED E ++ EDR+ ++++E
Sbjct: 959 LDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEE 1018
Query: 194 EEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEV 253
EE+ K + EV +R+++ + +LQ ++
Sbjct: 1019 EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQI 1078
Query: 254 DRLEDELGINKDRYK-SLADEMDST 277
D L+ +L ++ + +LA D T
Sbjct: 1079 DELKLQLAKKEEELQGALARGDDET 1103
Score = 46.8 bits (106), Expect = 9e-05
Identities = 50/248 (20%), Positives = 103/248 (41%), Gaps = 14/248 (5%)
Query: 42 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 101
+V +++L +E+L+ K K + +LEE E++ E L ++Q E +
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAE 905
Query: 102 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
+EE K E ++ + LE+R +++EER L N+ K+ + +D + +
Sbjct: 906 AEEMRARLAAKKQELEEILHD-------LESRVEEEEERNQILQNEKKKMQAHIQDLEEQ 958
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE-------ELKVVGNSLKSLEVSEEKA 214
DE ++ E AE ++K + +I LE+ E K++ + + +
Sbjct: 959 LDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEE 1018
Query: 215 NQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
++ + KT ++L+K +L+ E +D+ L ++
Sbjct: 1019 EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQI 1078
Query: 275 DSTFAELA 282
D +LA
Sbjct: 1079 DELKLQLA 1086
Score = 46.4 bits (105), Expect = 1e-04
Identities = 49/249 (19%), Positives = 98/249 (39%), Gaps = 10/249 (4%)
Query: 13 LEKDNAMDKADTCEQQARDA--NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKD 70
L K+NA+ + Q + + +EK + E QK+ + E+L K +LE
Sbjct: 1104 LHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKR--DLSEELEALKTELEDTLDT 1161
Query: 71 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
+++ T E EVA L + +EE+ + E + +Q+ A + E K
Sbjct: 1162 TAAQQELRTKREQEVAELKK---ALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRF 1218
Query: 131 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 190
+ +++++ ++ +L + + +S+ +KL EL +V GD
Sbjct: 1219 KANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHA---KVSEGDRLR 1275
Query: 191 SELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQ 250
EL E+ + N L ++ E+A ++ +F + L
Sbjct: 1276 VELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLS 1335
Query: 251 KEVDRLEDE 259
+ +LE+E
Sbjct: 1336 SRIRQLEEE 1344
Score = 45.2 bits (102), Expect = 3e-04
Identities = 53/288 (18%), Positives = 115/288 (39%), Gaps = 11/288 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEK--VNEEVRELQKK---LAQVEE 55
+D ++ A LEK E+++ A E+ E RE + K LA+ E
Sbjct: 1434 VDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALE 1493
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ + K + E+ NK L + L +++ +V ++++ + LE+ E T ++L +
Sbjct: 1494 EALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELED 1553
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE--ARLLAEDADGKSDEVSRKLAFVE 173
Q+ ++ +V + ER Q ++ E RLL + E+ +L
Sbjct: 1554 ELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQV----RELEAELEDER 1609
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXX 233
+ +A K + + +LE +++ + + K +++++
Sbjct: 1610 KQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRD 1669
Query: 234 XXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K +K L+ E+ +L++EL ++ + E D E+
Sbjct: 1670 EIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEI 1717
Score = 42.7 bits (96), Expect = 0.001
Identities = 42/200 (21%), Positives = 92/200 (46%), Gaps = 17/200 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ-------VEED 56
++K Q ++ + + +Q ++ + +K++ +V+EL K+++ + E
Sbjct: 1222 LEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEK 1281
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+N+L+ + LEE EK+ + A+L ++Q +E L++ + ++
Sbjct: 1282 ASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRI--- 1338
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
+Q +E N L+ + +++EE L Q+ L ++ AD K +V L +E
Sbjct: 1339 RQLEEEKNS----LQEQQEEEEEARKNLEKQV--LALQSQLADTKK-KVDDDLGTIESLE 1391
Query: 177 EVAEDRVKSGDAKISELEEE 196
E + +K +A LEE+
Sbjct: 1392 EAKKKLLKDAEALSQRLEEK 1411
Score = 40.3 bits (90), Expect = 0.007
Identities = 36/204 (17%), Positives = 77/204 (37%), Gaps = 3/204 (1%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 73
EK D+ C Q + +A+ + + + + ++ +EE L + ++ K +
Sbjct: 1000 EKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRK 1059
Query: 74 KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
+ + T + ++A L ++ +++ L K EE Q L N KV+
Sbjct: 1060 LDGETTDLQDQIAELQAQIDELKLQLAKKEEE---LQGALARGDDETLHKNNALKVVREL 1116
Query: 134 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 193
Q E + ++ + S+E+ +ED L+ + + + E+
Sbjct: 1117 QAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEV 1176
Query: 194 EEELKVVGNSLKSLEVSEEKANQR 217
E K + K+ E + QR
Sbjct: 1177 AELKKALEEETKNHEAQIQDMRQR 1200
Score = 38.7 bits (86), Expect = 0.023
Identities = 43/259 (16%), Positives = 104/259 (40%), Gaps = 10/259 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+ ++ ++ A K E + + ++ ++ + N + + E +++Q + +EE L +
Sbjct: 907 EEMRARLAAKKQELEEILHDLESRVEEEEERN---QILQNEKKKMQAHIQDLEEQLDEEE 963
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ + E ++ E E+ L + + ++ + E+R +L E ++ A
Sbjct: 964 GARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAK 1023
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
++ E EER+ + +E DG++ ++ ++A EL+ D
Sbjct: 1024 NLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIA----ELQAQID 1079
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXX 241
+K ++++ EEEL+ + + A + V E
Sbjct: 1080 ELK---LQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNK 1136
Query: 242 XXKTVKKLQKEVDRLEDEL 260
K + L +E++ L+ EL
Sbjct: 1137 AEKQKRDLSEELEALKTEL 1155
Score = 36.7 bits (81), Expect = 0.092
Identities = 29/134 (21%), Positives = 67/134 (50%), Gaps = 10/134 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A+K K +A + + + + EQ ++A RA N+ VR +KKL ++
Sbjct: 1807 AVKSKFKATISALEAKIGQLE--EQLEQEAKERAA-ANKLVRRTEKKLKEIFM------- 1856
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
++E + ++ ++Q+ A + L R++++ EE+ ++ Q++L +A ++ +
Sbjct: 1857 QVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEG 1916
Query: 123 NNRMCKVLENRAQQ 136
+R L+NR ++
Sbjct: 1917 LSREVSTLKNRLRR 1930
>BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 68.1 bits (159), Expect = 3e-11
Identities = 55/255 (21%), Positives = 112/255 (43%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ R L K++ ++E +L + + A ++ E L EA++
Sbjct: 1575 QFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIE 1634
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
A N+ ++ + L K + + Q++L EA+ S DE K E + + E + QL
Sbjct: 1635 AANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQE 1694
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
+L + A+ + DE++ ++ D + +A+I++LEEEL+ ++++
Sbjct: 1695 ELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMEL 1754
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
L K +V+ + K+L+ ++ LE G K +
Sbjct: 1755 LNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELE---GAVKSK 1811
Query: 267 YKSLADEMDSTFAEL 281
+K+ +++ +L
Sbjct: 1812 FKATISALEAKIGQL 1826
Score = 60.5 bits (140), Expect = 7e-09
Identities = 59/298 (19%), Positives = 131/298 (43%), Gaps = 17/298 (5%)
Query: 2 DAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
+A +K+ +A+ L + + A++ + E+Q + E + ++ K + ++E+
Sbjct: 1477 EAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRA 1536
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGTAQQKLLE 115
+ ++E+ LEE E +L ATE L +Q Q E DL+ +E++ ++ L++
Sbjct: 1537 LEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIK 1596
Query: 116 AQQSAD---ENNRMCKVLENRAQQDEE-RMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
+ + E+ R + L +++ E + L Q++ A ++ + ++ ++
Sbjct: 1597 QVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKD 1656
Query: 172 VEDELEVAE---DRV----KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXX 224
+ ELE A D + K + K+ LE E+ + L S E + A Q +E
Sbjct: 1657 YQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADE 1716
Query: 225 XXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
+ +L++E++ + + + DR++ ++D+ AELA
Sbjct: 1717 ITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELA 1774
Score = 55.2 bits (127), Expect = 2e-07
Identities = 59/260 (22%), Positives = 107/260 (41%), Gaps = 15/260 (5%)
Query: 22 ADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK----EKQ 77
A + E Q +D ++ + L ++ Q+EE+ KN L++ ++ EE EKQ
Sbjct: 1310 AASLESQLQDTQELLQEETRQKLNLSSRIRQLEEE----KNSLQEQQEEEEEARKNLEKQ 1365
Query: 78 LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQD 137
+ A ++++A +KV +E EE + Q +E LE +
Sbjct: 1366 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL 1425
Query: 138 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 197
++ D LT L R +A + + K + + LA E++ A + A+ E+E
Sbjct: 1426 QQEPDDLTVDLDHQRQVASNLEKKQKKFDQLLA--EEKSISARYAEERDRAEAEAREKET 1483
Query: 198 KVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLE 257
K + SL + E+A + EEF K V +L+K LE
Sbjct: 1484 KAL-----SLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALE 1538
Query: 258 DELGINKDRYKSLADEMDST 277
++ + + + L DE+ +T
Sbjct: 1539 QQVEEMRTQLEELEDELQAT 1558
Score = 54.4 bits (125), Expect = 4e-07
Identities = 38/200 (19%), Positives = 96/200 (48%), Gaps = 9/200 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ ++ ++ E + + + R L+ + +N E+ ++ AQ ++ + +
Sbjct: 1734 LEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAA-ERSAAQKSDNA---RQQ 1789
Query: 64 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
LE+ NK+L+ K ++L +A ++AL K+ Q+EE LE+ + A + + ++
Sbjct: 1790 LERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEK 1849
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
E + A Q +E+M++ ++K+ + E+A+ ++ + ++ EL+
Sbjct: 1850 KLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDD 1909
Query: 179 AEDRVKSGDAKISELEEELK 198
A + + ++S L+ L+
Sbjct: 1910 ATEANEGLSREVSTLKNRLR 1929
Score = 53.6 bits (123), Expect = 8e-07
Identities = 58/285 (20%), Positives = 121/285 (42%), Gaps = 14/285 (4%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D K++ A+ +K +D D E Q AN ++V +++R+LQ ++ + +L +
Sbjct: 1607 DERKQRALAVASKKKMEIDLKDL-EAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEAR 1665
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ +E EK+L + EAE+ Q++E+L SE A+Q+ E
Sbjct: 1666 ASRDEIFAQSKESEKKLKSLEAEIL-------QLQEELASSERARRHAEQERDELADEIT 1718
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
+ L + ++ E R+ QL +L+E + E + + + + ++ + EL
Sbjct: 1719 NSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERS 1778
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+ D +LE + K + L+ LE + K +
Sbjct: 1779 AAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERA 1838
Query: 241 XXXKTVKKLQKEVD----RLEDELGINKDRYKSLADEMDSTFAEL 281
K V++ +K++ ++EDE + D+YK ++ ++ +L
Sbjct: 1839 AANKLVRRTEKKLKEIFMQVEDERR-HADQYKEQMEKANARMKQL 1882
Score = 52.4 bits (120), Expect = 2e-06
Identities = 41/187 (21%), Positives = 87/187 (46%), Gaps = 4/187 (2%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT---EAEVAA-LNRKV 92
E+ +++ + + L+Q E+ L +KLE+ L+++ LT + +VA+ L +K
Sbjct: 1391 EEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQEPDDLTVDLDHQRQVASNLEKKQ 1450
Query: 93 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
++ ++ L + + S ++ A+ A E L ++ E ++ Q K+ R
Sbjct: 1451 KKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLR 1510
Query: 153 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
ED D+V + + +E E +V+ ++ ELE+EL+ ++ LEV+ +
Sbjct: 1511 ADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQ 1570
Query: 213 KANQRVE 219
+ E
Sbjct: 1571 AMKAQFE 1577
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/224 (20%), Positives = 99/224 (44%), Gaps = 8/224 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++++ + + + +A + D + ++ + +E R L+ ++AQ+EE+L ++
Sbjct: 1692 LQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSN 1751
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+E N + Q+ AE+AA Q+ + ++ E ++ + KL E + +
Sbjct: 1752 MELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSK 1811
Query: 124 NRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV-------SRKLAFVEDE 175
+ LE + Q EE+++Q + A L + K E+ R +++
Sbjct: 1812 FKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQ 1871
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+E A R+K ++ E EEE S + L+ + A + E
Sbjct: 1872 MEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANE 1915
Score = 50.4 bits (115), Expect = 7e-06
Identities = 49/278 (17%), Positives = 116/278 (41%), Gaps = 8/278 (2%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
K++ + +L+K ++ E Q +D R EE+ E ++ + + +L NK L
Sbjct: 1171 KREQEVAELKKA-LEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGL 1229
Query: 65 EQANKDLEEKEKQLTATEAEV----AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
E NK+L + K L +AE L+ +VQ++ + + + +K + Q
Sbjct: 1230 ETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNEL 1289
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
D + + + E + + + L +QL++ + L ++ + +S ++ +E+E +
Sbjct: 1290 DNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQ 1349
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
++ + + LE+++ + + L + + +E
Sbjct: 1350 EQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLE 1409
Query: 241 XXXKTVKKLQKEVDRLE---DELGINKDRYKSLADEMD 275
KL+K +RL+ D+L ++ D + +A ++
Sbjct: 1410 EKALAYDKLEKTKNRLQQEPDDLTVDLDHQRQVASNLE 1447
Score = 49.6 bits (113), Expect = 1e-05
Identities = 48/219 (21%), Positives = 106/219 (48%), Gaps = 18/219 (8%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
KKKMQA + + +D+ + Q+ L+ EKV E K+ ++EE+++L +++
Sbjct: 945 KKKMQAHIQDLEEQLDEEEGARQK-----LQLEKVTAEA-----KIKKMEEEILLLEDQN 994
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
+ K+ + E ++ +++A K + + + K E +++L + +++ E
Sbjct: 995 SKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELE 1054
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARL-LAEDADGKSDEVSRKLAFVEDEL---EVAE 180
+ + L+ ++++ +L Q+ E +L LA+ K +E+ LA +DE A
Sbjct: 1055 KAKRKLDGETTDLQDQIAELQAQIDELKLQLAK----KEEELQGALARGDDETLHKNNAL 1110
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
V+ A+I+EL+E+ + S E + ++ +E
Sbjct: 1111 KVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELE 1149
Score = 48.4 bits (110), Expect = 3e-05
Identities = 69/282 (24%), Positives = 129/282 (45%), Gaps = 20/282 (7%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQA-RDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +K K + K+E + +++ + QQ + N+ AE++ E EL + ++ L
Sbjct: 860 ELLKVKEKQTKVEGE--LEEMERKHQQLLEEKNILAEQLQAET-ELFAEAEEMRARLAAK 916
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K +LE+ DLE + ++ + +K+Q +DLE+ + A+QKL + +A
Sbjct: 917 KQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTA 976
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE-VA 179
+ K +E E DQ + +KE +L+ ED + E S +LA E++ + +A
Sbjct: 977 EAK---IKKMEEEILLLE---DQNSKFIKEKKLM-ED---RIAECSSQLAEEEEKAKNLA 1026
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
+ R K + IS+LEE LK + + LE ++ K + E
Sbjct: 1027 KIRNKQ-EVMISDLEERLKKEEKTRQELEKAKRKLD---GETTDLQDQIAELQAQIDELK 1082
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K ++LQ + R +DE ++K+ + E+ + AEL
Sbjct: 1083 LQLAKKEEELQGALARGDDET-LHKNNALKVVRELQAQIAEL 1123
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/161 (23%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Query: 38 KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 97
K + L+ K+ Q+EE L + ANK + EK+L +V R Q +E
Sbjct: 1811 KFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKE 1870
Query: 98 DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR---AQQDEERMDQLTNQLKEARLL 154
+EK+ R +++L EA++ A N + L+ A + E + + + LK
Sbjct: 1871 QMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1930
Query: 155 AEDADGKSDEVSRKLAFVED-ELEVAEDRVKSGDAKISELE 194
S R+ +E LE+++D +S + ++E +
Sbjct: 1931 GGPISFSSSRSGRRQLHLEGASLELSDDDTESKTSDVNETQ 1971
Score = 48.0 bits (109), Expect = 4e-05
Identities = 56/265 (21%), Positives = 114/265 (43%), Gaps = 27/265 (10%)
Query: 26 EQQARDANL-----RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 80
E QA+D L + KV E+ E+++K Q+ E+ + +L+ + E E+
Sbjct: 853 ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEM--- 909
Query: 81 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 140
A +AA +++++I DLE E Q L +N + K ++ Q EE+
Sbjct: 910 -RARLAAKKQELEEILHDLESRVEEEEERNQIL--------QNEK--KKMQAHIQDLEEQ 958
Query: 141 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED-------ELEVAEDRVKSGDAKISEL 193
+D+ ++ +L A+ K ++ ++ +ED E ++ EDR+ ++++E
Sbjct: 959 LDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEE 1018
Query: 194 EEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEV 253
EE+ K + EV +R+++ + +LQ ++
Sbjct: 1019 EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQI 1078
Query: 254 DRLEDELGINKDRYK-SLADEMDST 277
D L+ +L ++ + +LA D T
Sbjct: 1079 DELKLQLAKKEEELQGALARGDDET 1103
Score = 46.8 bits (106), Expect = 9e-05
Identities = 50/248 (20%), Positives = 103/248 (41%), Gaps = 14/248 (5%)
Query: 42 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 101
+V +++L +E+L+ K K + +LEE E++ E L ++Q E +
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAE 905
Query: 102 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
+EE K E ++ + LE+R +++EER L N+ K+ + +D + +
Sbjct: 906 AEEMRARLAAKKQELEEILHD-------LESRVEEEEERNQILQNEKKKMQAHIQDLEEQ 958
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE-------ELKVVGNSLKSLEVSEEKA 214
DE ++ E AE ++K + +I LE+ E K++ + + +
Sbjct: 959 LDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEE 1018
Query: 215 NQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
++ + KT ++L+K +L+ E +D+ L ++
Sbjct: 1019 EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQI 1078
Query: 275 DSTFAELA 282
D +LA
Sbjct: 1079 DELKLQLA 1086
Score = 46.4 bits (105), Expect = 1e-04
Identities = 49/249 (19%), Positives = 98/249 (39%), Gaps = 10/249 (4%)
Query: 13 LEKDNAMDKADTCEQQARDA--NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKD 70
L K+NA+ + Q + + +EK + E QK+ + E+L K +LE
Sbjct: 1104 LHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKR--DLSEELEALKTELEDTLDT 1161
Query: 71 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
+++ T E EVA L + +EE+ + E + +Q+ A + E K
Sbjct: 1162 TAAQQELRTKREQEVAELKK---ALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRF 1218
Query: 131 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 190
+ +++++ ++ +L + + +S+ +KL EL +V GD
Sbjct: 1219 KANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHA---KVSEGDRLR 1275
Query: 191 SELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQ 250
EL E+ + N L ++ E+A ++ +F + L
Sbjct: 1276 VELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLS 1335
Query: 251 KEVDRLEDE 259
+ +LE+E
Sbjct: 1336 SRIRQLEEE 1344
Score = 46.0 bits (104), Expect = 2e-04
Identities = 39/178 (21%), Positives = 82/178 (46%), Gaps = 8/178 (4%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
+++++ K + A+ Q+ + L +K+ + LQ Q +DL ++ + Q
Sbjct: 1387 IESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQ----QEPDDLTVDLDHQRQV 1442
Query: 68 NKDLEEKEK---QLTATEAEVAALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+LE+K+K QL A E ++A + + + E + + E ++ + + L EA ++ +E
Sbjct: 1443 ASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEF 1502
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
R K L + D + + E + + +E+ +L +EDEL+ ED
Sbjct: 1503 ERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATED 1560
Score = 45.2 bits (102), Expect = 3e-04
Identities = 53/288 (18%), Positives = 115/288 (39%), Gaps = 11/288 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEK--VNEEVRELQKK---LAQVEE 55
+D ++ A LEK E+++ A E+ E RE + K LA+ E
Sbjct: 1434 VDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALE 1493
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ + K + E+ NK L + L +++ +V ++++ + LE+ E T ++L +
Sbjct: 1494 EALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELED 1553
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE--ARLLAEDADGKSDEVSRKLAFVE 173
Q+ ++ +V + ER Q ++ E RLL + E+ +L
Sbjct: 1554 ELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQV----RELEAELEDER 1609
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXX 233
+ +A K + + +LE +++ + + K +++++
Sbjct: 1610 KQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRD 1669
Query: 234 XXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K +K L+ E+ +L++EL ++ + E D E+
Sbjct: 1670 EIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEI 1717
Score = 42.7 bits (96), Expect = 0.001
Identities = 42/200 (21%), Positives = 92/200 (46%), Gaps = 17/200 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ-------VEED 56
++K Q ++ + + +Q ++ + +K++ +V+EL K+++ + E
Sbjct: 1222 LEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEK 1281
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+N+L+ + LEE EK+ + A+L ++Q +E L++ + ++
Sbjct: 1282 ASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRI--- 1338
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
+Q +E N L+ + +++EE L Q+ L ++ AD K +V L +E
Sbjct: 1339 RQLEEEKNS----LQEQQEEEEEARKNLEKQV--LALQSQLADTKK-KVDDDLGTIESLE 1391
Query: 177 EVAEDRVKSGDAKISELEEE 196
E + +K +A LEE+
Sbjct: 1392 EAKKKLLKDAEALSQRLEEK 1411
Score = 40.3 bits (90), Expect = 0.007
Identities = 36/204 (17%), Positives = 77/204 (37%), Gaps = 3/204 (1%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 73
EK D+ C Q + +A+ + + + + ++ +EE L + ++ K +
Sbjct: 1000 EKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRK 1059
Query: 74 KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
+ + T + ++A L ++ +++ L K EE Q L N KV+
Sbjct: 1060 LDGETTDLQDQIAELQAQIDELKLQLAKKEEE---LQGALARGDDETLHKNNALKVVREL 1116
Query: 134 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 193
Q E + ++ + S+E+ +ED L+ + + + E+
Sbjct: 1117 QAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEV 1176
Query: 194 EEELKVVGNSLKSLEVSEEKANQR 217
E K + K+ E + QR
Sbjct: 1177 AELKKALEEETKNHEAQIQDMRQR 1200
Score = 38.7 bits (86), Expect = 0.023
Identities = 43/259 (16%), Positives = 104/259 (40%), Gaps = 10/259 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+ ++ ++ A K E + + ++ ++ + N + + E +++Q + +EE L +
Sbjct: 907 EEMRARLAAKKQELEEILHDLESRVEEEEERN---QILQNEKKKMQAHIQDLEEQLDEEE 963
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ + E ++ E E+ L + + ++ + E+R +L E ++ A
Sbjct: 964 GARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAK 1023
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
++ E EER+ + +E DG++ ++ ++A EL+ D
Sbjct: 1024 NLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIA----ELQAQID 1079
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXX 241
+K ++++ EEEL+ + + A + V E
Sbjct: 1080 ELK---LQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNK 1136
Query: 242 XXKTVKKLQKEVDRLEDEL 260
K + L +E++ L+ EL
Sbjct: 1137 AEKQKRDLSEELEALKTEL 1155
Score = 36.7 bits (81), Expect = 0.092
Identities = 29/134 (21%), Positives = 67/134 (50%), Gaps = 10/134 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A+K K +A + + + + EQ ++A RA N+ VR +KKL ++
Sbjct: 1807 AVKSKFKATISALEAKIGQLE--EQLEQEAKERAA-ANKLVRRTEKKLKEIFM------- 1856
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
++E + ++ ++Q+ A + L R++++ EE+ ++ Q++L +A ++ +
Sbjct: 1857 QVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEG 1916
Query: 123 NNRMCKVLENRAQQ 136
+R L+NR ++
Sbjct: 1917 LSREVSTLKNRLRR 1930
>BC000280-1|AAH00280.1| 471|Homo sapiens MYH10 protein protein.
Length = 471
Score = 68.1 bits (159), Expect = 3e-11
Identities = 55/255 (21%), Positives = 112/255 (43%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ R L K++ ++E +L + + A ++ E L EA++
Sbjct: 70 QFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIE 129
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
A N+ ++ + L K + + Q++L EA+ S DE K E + + E + QL
Sbjct: 130 AANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQE 189
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
+L + A+ + DE++ ++ D + +A+I++LEEEL+ ++++
Sbjct: 190 ELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMEL 249
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
L K +V+ + K+L+ ++ LE G K +
Sbjct: 250 LNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELE---GAVKSK 306
Query: 267 YKSLADEMDSTFAEL 281
+K+ +++ +L
Sbjct: 307 FKATISALEAKIGQL 321
Score = 59.3 bits (137), Expect = 2e-08
Identities = 59/283 (20%), Positives = 129/283 (45%), Gaps = 21/283 (7%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 60
++ M+ + KD+ E+ R + E++ ++ EL+ +L E+ L +N
Sbjct: 4 LRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVN 63
Query: 61 KNKLE-QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
++ Q +DL+ +++Q E + L ++V+++E +LE +ER Q+ L A +
Sbjct: 64 MQAMKAQFERDLQTRDEQ---NEEKKRLLIKQVRELEAELE--DERK---QRALAVASKK 115
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
E + K LE + + + D++ QL++ + +D + +E + + + +
Sbjct: 116 KMEID--LKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKES 173
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
E ++KS +A+I +L+EE L S E + A Q +E
Sbjct: 174 EKKLKSLEAEILQLQEE-------LASSERARRHAEQERDELADEITNSASGKSALLDEK 226
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
+ +L++E++ + + + DR++ ++D+ AELA
Sbjct: 227 RRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELA 269
Score = 54.4 bits (125), Expect = 4e-07
Identities = 38/200 (19%), Positives = 96/200 (48%), Gaps = 9/200 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ ++ ++ E + + + R L+ + +N E+ ++ AQ ++ + +
Sbjct: 229 LEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAA-ERSAAQKSDNA---RQQ 284
Query: 64 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
LE+ NK+L+ K ++L +A ++AL K+ Q+EE LE+ + A + + ++
Sbjct: 285 LERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEK 344
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
E + A Q +E+M++ ++K+ + E+A+ ++ + ++ EL+
Sbjct: 345 KLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDD 404
Query: 179 AEDRVKSGDAKISELEEELK 198
A + + ++S L+ L+
Sbjct: 405 ATEANEGLSREVSTLKNRLR 424
Score = 53.6 bits (123), Expect = 8e-07
Identities = 58/285 (20%), Positives = 121/285 (42%), Gaps = 14/285 (4%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D K++ A+ +K +D D E Q AN ++V +++R+LQ ++ + +L +
Sbjct: 102 DERKQRALAVASKKKMEIDLKDL-EAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEAR 160
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ +E EK+L + EAE+ Q++E+L SE A+Q+ E
Sbjct: 161 ASRDEIFAQSKESEKKLKSLEAEIL-------QLQEELASSERARRHAEQERDELADEIT 213
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
+ L + ++ E R+ QL +L+E + E + + + + ++ + EL
Sbjct: 214 NSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERS 273
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+ D +LE + K + L+ LE + K +
Sbjct: 274 AAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERA 333
Query: 241 XXXKTVKKLQKEVD----RLEDELGINKDRYKSLADEMDSTFAEL 281
K V++ +K++ ++EDE + D+YK ++ ++ +L
Sbjct: 334 AANKLVRRTEKKLKEIFMQVEDERR-HADQYKEQMEKANARMKQL 377
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/224 (20%), Positives = 99/224 (44%), Gaps = 8/224 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++++ + + + +A + D + ++ + +E R L+ ++AQ+EE+L ++
Sbjct: 187 LQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSN 246
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+E N + Q+ AE+AA Q+ + ++ E ++ + KL E + +
Sbjct: 247 MELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSK 306
Query: 124 NRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV-------SRKLAFVEDE 175
+ LE + Q EE+++Q + A L + K E+ R +++
Sbjct: 307 FKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQ 366
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+E A R+K ++ E EEE S + L+ + A + E
Sbjct: 367 MEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANE 410
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/161 (23%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Query: 38 KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 97
K + L+ K+ Q+EE L + ANK + EK+L +V R Q +E
Sbjct: 306 KFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKE 365
Query: 98 DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR---AQQDEERMDQLTNQLKEARLL 154
+EK+ R +++L EA++ A N + L+ A + E + + + LK
Sbjct: 366 QMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 425
Query: 155 AEDADGKSDEVSRKLAFVED-ELEVAEDRVKSGDAKISELE 194
S R+ +E LE+++D +S + ++E +
Sbjct: 426 GGPISFSSSRSGRRQLHLEGASLELSDDDTESKTSDVNETQ 466
Score = 36.7 bits (81), Expect = 0.092
Identities = 29/134 (21%), Positives = 67/134 (50%), Gaps = 10/134 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A+K K +A + + + + EQ ++A RA N+ VR +KKL ++
Sbjct: 302 AVKSKFKATISALEAKIGQLE--EQLEQEAKERAA-ANKLVRRTEKKLKEIFM------- 351
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
++E + ++ ++Q+ A + L R++++ EE+ ++ Q++L +A ++ +
Sbjct: 352 QVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEG 411
Query: 123 NNRMCKVLENRAQQ 136
+R L+NR ++
Sbjct: 412 LSREVSTLKNRLRR 425
Score = 32.3 bits (70), Expect = 2.0
Identities = 18/71 (25%), Positives = 34/71 (47%)
Query: 149 KEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
K+ R ED D+V + + +E E +V+ ++ ELE+EL+ ++ LE
Sbjct: 2 KQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLE 61
Query: 209 VSEEKANQRVE 219
V+ + + E
Sbjct: 62 VNMQAMKAQFE 72
>AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein
protein.
Length = 2018
Score = 68.1 bits (159), Expect = 3e-11
Identities = 55/255 (21%), Positives = 112/255 (43%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ R L K++ ++E +L + + A ++ E L EA++
Sbjct: 1617 QFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIE 1676
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
A N+ ++ + L K + + Q++L EA+ S DE K E + + E + QL
Sbjct: 1677 AANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQE 1736
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
+L + A+ + DE++ ++ D + +A+I++LEEEL+ ++++
Sbjct: 1737 ELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMEL 1796
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
L K +V+ + K+L+ ++ LE G K +
Sbjct: 1797 LNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELE---GAVKSK 1853
Query: 267 YKSLADEMDSTFAEL 281
+K+ +++ +L
Sbjct: 1854 FKATISALEAKIGQL 1868
Score = 60.5 bits (140), Expect = 7e-09
Identities = 59/298 (19%), Positives = 131/298 (43%), Gaps = 17/298 (5%)
Query: 2 DAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
+A +K+ +A+ L + + A++ + E+Q + E + ++ K + ++E+
Sbjct: 1519 EAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRA 1578
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGTAQQKLLE 115
+ ++E+ LEE E +L ATE L +Q Q E DL+ +E++ ++ L++
Sbjct: 1579 LEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIK 1638
Query: 116 AQQSAD---ENNRMCKVLENRAQQDEE-RMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
+ + E+ R + L +++ E + L Q++ A ++ + ++ ++
Sbjct: 1639 QVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKD 1698
Query: 172 VEDELEVAE---DRV----KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXX 224
+ ELE A D + K + K+ LE E+ + L S E + A Q +E
Sbjct: 1699 YQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADE 1758
Query: 225 XXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
+ +L++E++ + + + DR++ ++D+ AELA
Sbjct: 1759 ITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELA 1816
Score = 56.8 bits (131), Expect = 8e-08
Identities = 59/260 (22%), Positives = 108/260 (41%), Gaps = 15/260 (5%)
Query: 22 ADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK----EKQ 77
A + E Q +D ++ + L ++ Q+EE+ KN L++ ++ EE EKQ
Sbjct: 1352 AASLESQLQDTQELLQEETRQKLNLSSRIRQLEEE----KNSLQEQQEEEEEARKNLEKQ 1407
Query: 78 LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQD 137
+ A ++++A +KV +E EE + Q +E LE +
Sbjct: 1408 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL 1467
Query: 138 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 197
++ +D LT L R +A + + K + + LA E++ A + A+ E+E
Sbjct: 1468 QQELDDLTVDLDHQRQVASNLEKKQKKFDQLLA--EEKSISARYAEERDRAEAEAREKET 1525
Query: 198 KVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLE 257
K + SL + E+A + EEF K V +L+K LE
Sbjct: 1526 KAL-----SLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALE 1580
Query: 258 DELGINKDRYKSLADEMDST 277
++ + + + L DE+ +T
Sbjct: 1581 QQVEEMRTQLEELEDELQAT 1600
Score = 54.4 bits (125), Expect = 4e-07
Identities = 38/200 (19%), Positives = 96/200 (48%), Gaps = 9/200 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ ++ ++ E + + + R L+ + +N E+ ++ AQ ++ + +
Sbjct: 1776 LEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAA-ERSAAQKSDNA---RQQ 1831
Query: 64 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
LE+ NK+L+ K ++L +A ++AL K+ Q+EE LE+ + A + + ++
Sbjct: 1832 LERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEK 1891
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
E + A Q +E+M++ ++K+ + E+A+ ++ + ++ EL+
Sbjct: 1892 KLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDD 1951
Query: 179 AEDRVKSGDAKISELEEELK 198
A + + ++S L+ L+
Sbjct: 1952 ATEANEGLSREVSTLKNRLR 1971
Score = 53.6 bits (123), Expect = 8e-07
Identities = 58/285 (20%), Positives = 121/285 (42%), Gaps = 14/285 (4%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D K++ A+ +K +D D E Q AN ++V +++R+LQ ++ + +L +
Sbjct: 1649 DERKQRALAVASKKKMEIDLKDL-EAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEAR 1707
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ +E EK+L + EAE+ Q++E+L SE A+Q+ E
Sbjct: 1708 ASRDEIFAQSKESEKKLKSLEAEIL-------QLQEELASSERARRHAEQERDELADEIT 1760
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
+ L + ++ E R+ QL +L+E + E + + + + ++ + EL
Sbjct: 1761 NSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERS 1820
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+ D +LE + K + L+ LE + K +
Sbjct: 1821 AAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERA 1880
Query: 241 XXXKTVKKLQKEVD----RLEDELGINKDRYKSLADEMDSTFAEL 281
K V++ +K++ ++EDE + D+YK ++ ++ +L
Sbjct: 1881 AANKLVRRTEKKLKEIFMQVEDERR-HADQYKEQMEKANARMKQL 1924
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/224 (20%), Positives = 99/224 (44%), Gaps = 8/224 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++++ + + + +A + D + ++ + +E R L+ ++AQ+EE+L ++
Sbjct: 1734 LQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSN 1793
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+E N + Q+ AE+AA Q+ + ++ E ++ + KL E + +
Sbjct: 1794 MELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSK 1853
Query: 124 NRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV-------SRKLAFVEDE 175
+ LE + Q EE+++Q + A L + K E+ R +++
Sbjct: 1854 FKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQ 1913
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+E A R+K ++ E EEE S + L+ + A + E
Sbjct: 1914 MEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANE 1957
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/217 (20%), Positives = 97/217 (44%), Gaps = 7/217 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A++ ++ K + D+ + ++ E+ + AE +++ + E K LA + L KN
Sbjct: 1410 ALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE--KALAY--DKLEKTKN 1465
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L+Q +L++ L + L +K ++ ++ L + + S ++ A+ A E
Sbjct: 1466 RLQQ---ELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEARE 1522
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
L ++ E ++ Q K+ R ED D+V + + +E E +
Sbjct: 1523 KETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQ 1582
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
V+ ++ ELE+EL+ ++ LEV+ + + E
Sbjct: 1583 VEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFE 1619
Score = 50.4 bits (115), Expect = 7e-06
Identities = 49/278 (17%), Positives = 116/278 (41%), Gaps = 8/278 (2%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
K++ + +L+K ++ E Q +D R EE+ E ++ + + +L NK L
Sbjct: 1213 KREQEVAELKKA-LEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGL 1271
Query: 65 EQANKDLEEKEKQLTATEAEV----AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
E NK+L + K L +AE L+ +VQ++ + + + +K + Q
Sbjct: 1272 ETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNEL 1331
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
D + + + E + + + L +QL++ + L ++ + +S ++ +E+E +
Sbjct: 1332 DNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQ 1391
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
++ + + LE+++ + + L + + +E
Sbjct: 1392 EQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLE 1451
Query: 241 XXXKTVKKLQKEVDRLE---DELGINKDRYKSLADEMD 275
KL+K +RL+ D+L ++ D + +A ++
Sbjct: 1452 EKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLE 1489
Score = 49.6 bits (113), Expect = 1e-05
Identities = 48/219 (21%), Positives = 106/219 (48%), Gaps = 18/219 (8%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
KKKMQA + + +D+ + Q+ L+ EKV E K+ ++EE+++L +++
Sbjct: 987 KKKMQAHIQDLEEQLDEEEGARQK-----LQLEKVTAEA-----KIKKMEEEILLLEDQN 1036
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
+ K+ + E ++ +++A K + + + K E +++L + +++ E
Sbjct: 1037 SKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELE 1096
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARL-LAEDADGKSDEVSRKLAFVEDEL---EVAE 180
+ + L+ ++++ +L Q+ E +L LA+ K +E+ LA +DE A
Sbjct: 1097 KAKRKLDGETTDLQDQIAELQAQIDELKLQLAK----KEEELQGALARGDDETLHKNNAL 1152
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
V+ A+I+EL+E+ + S E + ++ +E
Sbjct: 1153 KVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELE 1191
Score = 48.4 bits (110), Expect = 3e-05
Identities = 69/282 (24%), Positives = 129/282 (45%), Gaps = 20/282 (7%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQA-RDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +K K + K+E + +++ + QQ + N+ AE++ E EL + ++ L
Sbjct: 902 ELLKVKEKQTKVEGE--LEEMERKHQQLLEEKNILAEQLQAET-ELFAEAEEMRARLAAK 958
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K +LE+ DLE + ++ + +K+Q +DLE+ + A+QKL + +A
Sbjct: 959 KQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTA 1018
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE-VA 179
+ K +E E DQ + +KE +L+ ED + E S +LA E++ + +A
Sbjct: 1019 EAK---IKKMEEEILLLE---DQNSKFIKEKKLM-ED---RIAECSSQLAEEEEKAKNLA 1068
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
+ R K + IS+LEE LK + + LE ++ K + E
Sbjct: 1069 KIRNKQ-EVMISDLEERLKKEEKTRQELEKAKRKLD---GETTDLQDQIAELQAQIDELK 1124
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K ++LQ + R +DE ++K+ + E+ + AEL
Sbjct: 1125 LQLAKKEEELQGALARGDDET-LHKNNALKVVRELQAQIAEL 1165
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/161 (23%), Positives = 70/161 (43%), Gaps = 4/161 (2%)
Query: 38 KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 97
K + L+ K+ Q+EE L + ANK + EK+L +V R Q +E
Sbjct: 1853 KFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKE 1912
Query: 98 DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR---AQQDEERMDQLTNQLKEARLL 154
+EK+ R +++L EA++ A N + L+ A + E + + + LK
Sbjct: 1913 QMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1972
Query: 155 AEDADGKSDEVSRKLAFVED-ELEVAEDRVKSGDAKISELE 194
S R+ +E LE+++D +S + ++E +
Sbjct: 1973 GGPISFSSSRSGRRQLHLEGASLELSDDDTESKTSDVNETQ 2013
Score = 48.0 bits (109), Expect = 4e-05
Identities = 56/265 (21%), Positives = 114/265 (43%), Gaps = 27/265 (10%)
Query: 26 EQQARDANL-----RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 80
E QA+D L + KV E+ E+++K Q+ E+ + +L+ + E E+
Sbjct: 895 ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEM--- 951
Query: 81 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 140
A +AA +++++I DLE E Q L +N + K ++ Q EE+
Sbjct: 952 -RARLAAKKQELEEILHDLESRVEEEEERNQIL--------QNEK--KKMQAHIQDLEEQ 1000
Query: 141 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED-------ELEVAEDRVKSGDAKISEL 193
+D+ ++ +L A+ K ++ ++ +ED E ++ EDR+ ++++E
Sbjct: 1001 LDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEE 1060
Query: 194 EEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEV 253
EE+ K + EV +R+++ + +LQ ++
Sbjct: 1061 EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQI 1120
Query: 254 DRLEDELGINKDRYK-SLADEMDST 277
D L+ +L ++ + +LA D T
Sbjct: 1121 DELKLQLAKKEEELQGALARGDDET 1145
Score = 46.8 bits (106), Expect = 9e-05
Identities = 50/248 (20%), Positives = 103/248 (41%), Gaps = 14/248 (5%)
Query: 42 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 101
+V +++L +E+L+ K K + +LEE E++ E L ++Q E +
Sbjct: 888 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAE 947
Query: 102 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
+EE K E ++ + LE+R +++EER L N+ K+ + +D + +
Sbjct: 948 AEEMRARLAAKKQELEEILHD-------LESRVEEEEERNQILQNEKKKMQAHIQDLEEQ 1000
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE-------ELKVVGNSLKSLEVSEEKA 214
DE ++ E AE ++K + +I LE+ E K++ + + +
Sbjct: 1001 LDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEE 1060
Query: 215 NQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
++ + KT ++L+K +L+ E +D+ L ++
Sbjct: 1061 EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQI 1120
Query: 275 DSTFAELA 282
D +LA
Sbjct: 1121 DELKLQLA 1128
Score = 46.4 bits (105), Expect = 1e-04
Identities = 49/249 (19%), Positives = 98/249 (39%), Gaps = 10/249 (4%)
Query: 13 LEKDNAMDKADTCEQQARDA--NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKD 70
L K+NA+ + Q + + +EK + E QK+ + E+L K +LE
Sbjct: 1146 LHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKR--DLSEELEALKTELEDTLDT 1203
Query: 71 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
+++ T E EVA L + +EE+ + E + +Q+ A + E K
Sbjct: 1204 TAAQQELRTKREQEVAELKK---ALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRF 1260
Query: 131 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 190
+ +++++ ++ +L + + +S+ +KL EL +V GD
Sbjct: 1261 KANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHA---KVSEGDRLR 1317
Query: 191 SELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQ 250
EL E+ + N L ++ E+A ++ +F + L
Sbjct: 1318 VELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLS 1377
Query: 251 KEVDRLEDE 259
+ +LE+E
Sbjct: 1378 SRIRQLEEE 1386
Score = 45.2 bits (102), Expect = 3e-04
Identities = 53/288 (18%), Positives = 115/288 (39%), Gaps = 11/288 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEK--VNEEVRELQKK---LAQVEE 55
+D ++ A LEK E+++ A E+ E RE + K LA+ E
Sbjct: 1476 VDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALE 1535
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ + K + E+ NK L + L +++ +V ++++ + LE+ E T ++L +
Sbjct: 1536 EALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELED 1595
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE--ARLLAEDADGKSDEVSRKLAFVE 173
Q+ ++ +V + ER Q ++ E RLL + E+ +L
Sbjct: 1596 ELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQV----RELEAELEDER 1651
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXX 233
+ +A K + + +LE +++ + + K +++++
Sbjct: 1652 KQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRD 1711
Query: 234 XXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K +K L+ E+ +L++EL ++ + E D E+
Sbjct: 1712 EIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEI 1759
Score = 42.7 bits (96), Expect = 0.001
Identities = 42/200 (21%), Positives = 92/200 (46%), Gaps = 17/200 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ-------VEED 56
++K Q ++ + + +Q ++ + +K++ +V+EL K+++ + E
Sbjct: 1264 LEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEK 1323
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+N+L+ + LEE EK+ + A+L ++Q +E L++ + ++
Sbjct: 1324 ASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRI--- 1380
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
+Q +E N L+ + +++EE L Q+ L ++ AD K +V L +E
Sbjct: 1381 RQLEEEKNS----LQEQQEEEEEARKNLEKQV--LALQSQLADTKK-KVDDDLGTIESLE 1433
Query: 177 EVAEDRVKSGDAKISELEEE 196
E + +K +A LEE+
Sbjct: 1434 EAKKKLLKDAEALSQRLEEK 1453
Score = 40.3 bits (90), Expect = 0.007
Identities = 36/204 (17%), Positives = 77/204 (37%), Gaps = 3/204 (1%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 73
EK D+ C Q + +A+ + + + + ++ +EE L + ++ K +
Sbjct: 1042 EKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRK 1101
Query: 74 KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
+ + T + ++A L ++ +++ L K EE Q L N KV+
Sbjct: 1102 LDGETTDLQDQIAELQAQIDELKLQLAKKEEE---LQGALARGDDETLHKNNALKVVREL 1158
Query: 134 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 193
Q E + ++ + S+E+ +ED L+ + + + E+
Sbjct: 1159 QAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEV 1218
Query: 194 EEELKVVGNSLKSLEVSEEKANQR 217
E K + K+ E + QR
Sbjct: 1219 AELKKALEEETKNHEAQIQDMRQR 1242
Score = 38.7 bits (86), Expect = 0.023
Identities = 43/259 (16%), Positives = 104/259 (40%), Gaps = 10/259 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+ ++ ++ A K E + + ++ ++ + N + + E +++Q + +EE L +
Sbjct: 949 EEMRARLAAKKQELEEILHDLESRVEEEEERN---QILQNEKKKMQAHIQDLEEQLDEEE 1005
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ + E ++ E E+ L + + ++ + E+R +L E ++ A
Sbjct: 1006 GARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAK 1065
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
++ E EER+ + +E DG++ ++ ++A EL+ D
Sbjct: 1066 NLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIA----ELQAQID 1121
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXX 241
+K ++++ EEEL+ + + A + V E
Sbjct: 1122 ELK---LQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNK 1178
Query: 242 XXKTVKKLQKEVDRLEDEL 260
K + L +E++ L+ EL
Sbjct: 1179 AEKQKRDLSEELEALKTEL 1197
Score = 36.7 bits (81), Expect = 0.092
Identities = 29/134 (21%), Positives = 67/134 (50%), Gaps = 10/134 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A+K K +A + + + + EQ ++A RA N+ VR +KKL ++
Sbjct: 1849 AVKSKFKATISALEAKIGQLE--EQLEQEAKERAA-ANKLVRRTEKKLKEIFM------- 1898
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
++E + ++ ++Q+ A + L R++++ EE+ ++ Q++L +A ++ +
Sbjct: 1899 QVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEG 1958
Query: 123 NNRMCKVLENRAQQ 136
+R L+NR ++
Sbjct: 1959 LSREVSTLKNRLRR 1972
>AF362887-1|AAK51964.1| 142|Homo sapiens tropomyosin 4-anaplastic
lymphoma kinase fusion protein minor isoform protein.
Length = 142
Score = 66.9 bits (156), Expect = 8e-11
Identities = 34/111 (30%), Positives = 61/111 (54%)
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
+++ R E A+ + ++R++ VE+EL+ A++R + + K +LEEELK V N+LKS
Sbjct: 2 EVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERAEVSELKCGDLEEELKNVTNNLKS 61
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLE 257
LE + EK +++ +++ +TV KL+K +D LE
Sbjct: 62 LEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLE 112
Score = 56.0 bits (129), Expect = 1e-07
Identities = 30/113 (26%), Positives = 66/113 (58%), Gaps = 3/113 (2%)
Query: 69 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
+++E + + EAEVA+LNR++Q +EE+L++++ER+ ++ K + ++ K
Sbjct: 1 REVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERAEVSELKCGDLEEELKNVTNNLK 60
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE---DELEV 178
LE +++ E+ D+ ++K ++A+ +++ R +A +E D+LEV
Sbjct: 61 SLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEV 113
>Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9,
non-muscle protein.
Length = 1960
Score = 66.1 bits (154), Expect = 1e-10
Identities = 52/255 (20%), Positives = 115/255 (45%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ ++L +++ ++E +L + + A ++ E L EA +
Sbjct: 1568 QFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 1627
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+ N+ + + L K + + ++L + + S +E K E + + E M QL
Sbjct: 1628 SANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQE 1687
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
+L A A + DE++ ++A + +A + + +A+I++LEEEL+ + +
Sbjct: 1688 ELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTEL 1747
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
+ +KAN ++++ + K+L+ ++ +E G K +
Sbjct: 1748 INDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEME---GTVKSK 1804
Query: 267 YKSLADEMDSTFAEL 281
YK+ +++ A+L
Sbjct: 1805 YKASITALEAKIAQL 1819
Score = 63.7 bits (148), Expect = 7e-10
Identities = 50/207 (24%), Positives = 108/207 (52%), Gaps = 23/207 (11%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ ++ ++ E + + + + ANL+ +++N ++ L++ AQ E+ + +
Sbjct: 1727 LEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLN-LERSHAQKNENA---RQQ 1782
Query: 64 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLE-KSEERSGTAQQ------ 111
LE+ NK+L+ K +++ T +A + AL K+ Q+EE L+ +++ER +Q
Sbjct: 1783 LERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEK 1842
Query: 112 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
KL + D+ R + +++A + R+ QL QL+EA A+ A+ ++ R+L
Sbjct: 1843 KLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQREL-- 1900
Query: 172 VEDELEVAEDRVKSGDAKISELEEELK 198
ED E A+ + + ++S L+ +L+
Sbjct: 1901 -EDATETAD----AMNREVSSLKNKLR 1922
Score = 61.7 bits (143), Expect = 3e-09
Identities = 59/252 (23%), Positives = 106/252 (42%), Gaps = 7/252 (2%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E Q +D ++ N + L KL QVE++ + +LE+ + EKQ+ A+V
Sbjct: 1307 ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQV 1366
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
A + +K++ LE +EE Q+ L Q +E LE + ++ +D L
Sbjct: 1367 ADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLL 1426
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
L R A + + K + + LA E++ A+ + A+ E+E K +
Sbjct: 1427 VDLDHQRQSACNLEKKQKKFDQLLA--EEKTISAKYAEERDRAEAEAREKETKAL----- 1479
Query: 206 SLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKD 265
SL + E+A ++ E K+V +L+K LE ++ K
Sbjct: 1480 SLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKT 1539
Query: 266 RYKSLADEMDST 277
+ + L DE+ +T
Sbjct: 1540 QLEELEDELQAT 1551
Score = 55.2 bits (127), Expect = 2e-07
Identities = 45/224 (20%), Positives = 97/224 (43%), Gaps = 7/224 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M +++++ A + K A + D + +++ + EE R L+ ++AQ+EE+L
Sbjct: 1682 MIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEE 1741
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ E N L++ Q+ ++ Q+ E ++ E ++ + KL E + +
Sbjct: 1742 QGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTV 1801
Query: 121 DENNR-MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+ LE + Q EE++D N+ KE + + ++ L V+DE A
Sbjct: 1802 KSKYKASITALEAKIAQLEEQLD---NETKERQAACKQVRRTEKKLKDVLLQVDDERRNA 1858
Query: 180 E---DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
E D+ ++ +L+ +L+ + S K + +E+
Sbjct: 1859 EQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELED 1902
Score = 54.8 bits (126), Expect = 3e-07
Identities = 56/254 (22%), Positives = 109/254 (42%), Gaps = 13/254 (5%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 73
E+D A +A E +A E+ E+ EL++ Q ++ + + K + E
Sbjct: 1463 ERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHE 1522
Query: 74 KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
EK A E +V + +++++E++L+ +E+ + L+A ++ E + L+ R
Sbjct: 1523 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVN-LQAMKAQFERD-----LQGR 1576
Query: 134 AQQDEERMDQLTNQLKEARL-LAEDADGKSDEVS--RKLAFVEDELEVAEDRV-KSGDAK 189
+Q EE+ QL Q++E L ++ +S V+ +KL +LE D K+ D
Sbjct: 1577 DEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEA 1636
Query: 190 ISE---LEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTV 246
I + L+ ++K L S E+ + +E +
Sbjct: 1637 IKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAK 1696
Query: 247 KKLQKEVDRLEDEL 260
++ Q+E D L DE+
Sbjct: 1697 RQAQQERDELADEI 1710
Score = 53.6 bits (123), Expect = 8e-07
Identities = 56/236 (23%), Positives = 111/236 (47%), Gaps = 30/236 (12%)
Query: 3 AIKKKMQAMK-LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
A K + +A+K L K A K C ++ D E++ + +E +KKL +E ++I +
Sbjct: 1629 ANKNRDEAIKQLRKLQAQMK--DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQ 1686
Query: 62 NKL---EQANKDLEEKEKQLTATEA-----------EVAALNRKVQQIEEDLEKSEERSG 107
+L E+A + +++ +L A E L ++ Q+EE+LE+ + +
Sbjct: 1687 EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTE 1746
Query: 108 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG--KS--- 162
+L +A D+ N + + AQ++E QL Q KE ++ ++ +G KS
Sbjct: 1747 LINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYK 1806
Query: 163 ---DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
+ K+A +E++L+ ++ ++ E++LK V L+V +E+ N
Sbjct: 1807 ASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDV-----LLQVDDERRN 1857
Score = 53.2 bits (122), Expect = 1e-06
Identities = 55/274 (20%), Positives = 116/274 (42%), Gaps = 15/274 (5%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN-- 62
+++ Q ++ EK E+Q + +K+ E + KL ++EE+ I+ ++
Sbjct: 928 EERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQN 987
Query: 63 -KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
KL + K LE++ + T E ++ + +++ K E +++L ++
Sbjct: 988 CKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLK---NKHEAMITDLEERLRREEKQRQ 1044
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAEDADGKSDEVSRKLAFVEDELEVAE 180
E + + LE + +++ +L Q+ E ++ LA+ K +E+ LA VE+E
Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAK----KEEELQAALARVEEEAAQKN 1100
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+K KI ELE ++ + L+S S KA ++ +
Sbjct: 1101 MALK----KIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA 1156
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
+ K ++EV+ L+ L +++ EM
Sbjct: 1157 AQQELRSKREQEVNILKKTLEEEAKTHEAQIQEM 1190
Score = 50.4 bits (115), Expect = 7e-06
Identities = 43/214 (20%), Positives = 98/214 (45%), Gaps = 4/214 (1%)
Query: 9 QAMKLEKDNAMDKA--DTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
Q +L++D ++A + E+Q RD E + E+ + A +E + ++
Sbjct: 1112 QISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNI 1171
Query: 67 ANKDLEEKEKQLTATEAEVAALNRK-VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
K LEE+ K A E+ + + V+++ E LE+++ ++ + E
Sbjct: 1172 LKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELAN 1231
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
KVL E + ++ QL+E ++ + + E++ K+ ++ EL+ +
Sbjct: 1232 EVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQ 1291
Query: 186 GDAKISELEEELKVVGNSLK-SLEVSEEKANQRV 218
D+K S+L ++ + + L+ + E+ +E+ Q++
Sbjct: 1292 SDSKSSKLTKDFSALESQLQDTQELLQEENRQKL 1325
Score = 49.6 bits (113), Expect = 1e-05
Identities = 45/189 (23%), Positives = 90/189 (47%), Gaps = 6/189 (3%)
Query: 36 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT--EAEVAALNRKVQ 93
AE+V ++++ + L+Q E+ + +KLE+ L+++ L +A N + +
Sbjct: 1383 AEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKK 1442
Query: 94 QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQ---LTNQLKE 150
Q + D +EE++ +A+ + A+ + K L + A+ EE M+Q L K+
Sbjct: 1443 QKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKAL-SLARALEEAMEQKAELERLNKQ 1501
Query: 151 ARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVS 210
R ED D+V + + +E E +V+ ++ ELE+EL+ ++ LEV+
Sbjct: 1502 FRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVN 1561
Query: 211 EEKANQRVE 219
+ + E
Sbjct: 1562 LQAMKAQFE 1570
Score = 48.4 bits (110), Expect = 3e-05
Identities = 44/228 (19%), Positives = 96/228 (42%), Gaps = 8/228 (3%)
Query: 49 KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 108
++++ EE+++ + +L + + E +LT E + L + Q++E L+ E
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAE 898
Query: 109 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
A++ E +C LE R +++EER L + K+ + ++ + + +E
Sbjct: 899 AEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEES- 957
Query: 169 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXX 228
+L++ ++V + +AK+ +LEEE ++ + L ++ R+ EF
Sbjct: 958 ---ARQKLQL--EKVTT-EAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE 1011
Query: 229 XXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE-LGINKDRYKSLADEMD 275
+ L++ + R E + + K R K D D
Sbjct: 1012 EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTD 1059
Score = 48.4 bits (110), Expect = 3e-05
Identities = 61/275 (22%), Positives = 113/275 (41%), Gaps = 14/275 (5%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
K++ +L +N + + +T + Q L+ ++ + EL + ++ L K +LE+
Sbjct: 856 KVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEE 915
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
DLE + ++ + A +K+QQ ++LE+ E +A+QKL Q
Sbjct: 916 ICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKL---QLEKVTTEAK 972
Query: 127 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
K LE ++ DQ KE +LL ED + E + L E++ +
Sbjct: 973 LKKLE---EEQIILEDQNCKLAKEKKLL-ED---RIAEFTTNLTEEEEKSKSLAKLKNKH 1025
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTV 246
+A I++LEE L+ + LE + K + K
Sbjct: 1026 EAMITDLEERLRREEKQRQELEKTRRKLE---GDSTDLSDQIAELQAQIAELKMQLAKKE 1082
Query: 247 KKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++LQ + R+E+E K + E++S +EL
Sbjct: 1083 EELQAALARVEEEAAQKNMALKKIR-ELESQISEL 1116
Score = 48.4 bits (110), Expect = 3e-05
Identities = 46/231 (19%), Positives = 105/231 (45%), Gaps = 13/231 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ + + + KLE++ + + C+ A++ L +++ E L ++ + + L
Sbjct: 964 LEKVTTEAKLKKLEEEQIILEDQNCKL-AKEKKLLEDRIAEFTTNLTEE-EEKSKSLAKL 1021
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK--SEERSGTAQQKLLEAQQ 118
KNK E DLEE+ ++ E+ RK++ DL +E ++ A+ K+ A++
Sbjct: 1022 KNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKK 1081
Query: 119 SADENNRMCKVLENRAQQD---------EERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
+ + +V E AQ++ E ++ +L L+ R A+ + ++ +L
Sbjct: 1082 EEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEEL 1141
Query: 170 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
++ ELE D + S+ E+E+ ++ +L+ + E Q + +
Sbjct: 1142 EALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQ 1192
Score = 47.6 bits (108), Expect = 5e-05
Identities = 51/220 (23%), Positives = 101/220 (45%), Gaps = 21/220 (9%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE----KVNEEVRELQKKLAQVEEDLIL 59
+K K +AM + + + + + Q+ + E +++++ ELQ ++A+++ L
Sbjct: 1021 LKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAK 1080
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
+ +L+ A +EE+ Q ++ L ++ +++EDLE SE S +K Q
Sbjct: 1081 KEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLE-SERASRNKAEK-----QK 1134
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
D + + LE + E+ +D Q +E R E EV+ +E+E +
Sbjct: 1135 RD----LGEELEALKTELEDTLDSTAAQ-QELRSKREQ------EVNILKKTLEEEAKTH 1183
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
E +++ K S+ EEL K ++ + EKA Q +E
Sbjct: 1184 EAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLE 1223
Score = 46.8 bits (106), Expect = 9e-05
Identities = 42/184 (22%), Positives = 86/184 (46%), Gaps = 8/184 (4%)
Query: 41 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 100
++V +LQ +L V L + +K + KD E QL T+ + NR+ + L+
Sbjct: 1273 DKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLK 1332
Query: 101 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA----RLLAE 156
+ E+ + +++L E +++ + L + +++M+ L+ A R L +
Sbjct: 1333 QVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQK 1392
Query: 157 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
D +G S K+A D+LE + R++ ++ +L +L S +LE ++K +Q
Sbjct: 1393 DLEGLSQRHEEKVA-AYDKLEKTKTRLQQ---ELDDLLVDLDHQRQSACNLEKKQKKFDQ 1448
Query: 217 RVEE 220
+ E
Sbjct: 1449 LLAE 1452
Score = 46.0 bits (104), Expect = 2e-04
Identities = 33/150 (22%), Positives = 67/150 (44%), Gaps = 4/150 (2%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A K + +LE+ N K + Q + +++ K + L+ K+AQ+EE L
Sbjct: 1773 AQKNENARQQLERQNKELKV---KLQEMEGTVKS-KYKASITALEAKIAQLEEQLDNETK 1828
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+ + A K + EK+L +V R +Q ++ +K+ R +++L EA++ A
Sbjct: 1829 ERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQR 1888
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
N + L+ + E D + ++ +
Sbjct: 1889 ANASRRKLQRELEDATETADAMNREVSSLK 1918
Score = 42.7 bits (96), Expect = 0.001
Identities = 48/220 (21%), Positives = 95/220 (43%), Gaps = 7/220 (3%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
+Q +K + K E + + E+ E L+K++A + + K K+E +
Sbjct: 1317 LQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDS 1376
Query: 68 NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD-ENNRM 126
LE E+ + ++ L+++ ++ +K E+ QQ+L + D +
Sbjct: 1377 VGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSA 1436
Query: 127 CKVLENRAQQDEERMDQLTNQLKEA----RLLAEDADGKSDEVSRKLAFVEDELEVAE-D 181
C + + + + D+ ++ T K A R AE + ++ +S A E + AE +
Sbjct: 1437 CNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELE 1496
Query: 182 RV-KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
R+ K ++ +L VG S+ LE S+ Q+VEE
Sbjct: 1497 RLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEE 1536
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/138 (23%), Positives = 68/138 (49%), Gaps = 5/138 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K K+Q M+ + KA +A+ A L E+++ E +E Q QV K+
Sbjct: 1790 LKVKLQEMEGTVKSKY-KASITALEAKIAQLE-EQLDNETKERQAACKQVRRTEKKLKDV 1847
Query: 64 LEQAN---KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
L Q + ++ E+ + Q + L R++++ EE+ +++ Q++L +A ++A
Sbjct: 1848 LLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETA 1907
Query: 121 DENNRMCKVLENRAQQDE 138
D NR L+N+ ++ +
Sbjct: 1908 DAMNREVSSLKNKLRRGD 1925
Score = 40.3 bits (90), Expect = 0.007
Identities = 41/225 (18%), Positives = 98/225 (43%), Gaps = 9/225 (4%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ K++ ++ EK++ ++ + E+ + + ++ +V +++KK+ L +
Sbjct: 1326 SLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEE 1385
Query: 63 KLEQANKDLE----EKEKQLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLE 115
+ KDLE E+++ A + R Q++++ DL+ + + ++K +
Sbjct: 1386 VKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKK 1445
Query: 116 AQQ-SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
Q A+E K E R + + E ++ T L AR L E + K+ E+ R
Sbjct: 1446 FDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKA-ELERLNKQFRT 1504
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
E+E + ELE+ + + ++ ++ E+ ++
Sbjct: 1505 EMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQ 1549
Score = 39.9 bits (89), Expect = 0.010
Identities = 46/223 (20%), Positives = 97/223 (43%), Gaps = 13/223 (5%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ---VEEDLI-- 58
++K Q ++ E+ ++ Q D+ + +KV +++ELQ K + V +L
Sbjct: 1215 LEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADK 1274
Query: 59 LNKNKLEQANKD--LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+ K ++E N L + + + + + +AL ++Q +E L++ + + KL +
Sbjct: 1275 VTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQV 1334
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG---KSDEVSRKLAFVE 173
+ + + E E+++ L Q+ + + ED+ G ++EV RKL +
Sbjct: 1335 EDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKL---Q 1391
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
+LE R + A +LE+ + L L V + Q
Sbjct: 1392 KDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQ 1434
Score = 33.1 bits (72), Expect = 1.1
Identities = 35/183 (19%), Positives = 82/183 (44%), Gaps = 22/183 (12%)
Query: 34 LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 93
L+ + EE+ +++L +V E + +N+L + +E + QL A + ++ +
Sbjct: 838 LQVSRQEEEMMAKEEELVKVREKQLAAENRLTE----METLQSQLMAEKLQLQEQLQAET 893
Query: 94 QIEEDLEKSEERSGTAQQKLLEA----QQSADENNRMC-------KVLENRAQQDEERMD 142
++ + E+ R +Q+L E + +E C K ++ Q+ EE+++
Sbjct: 894 ELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLE 953
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVED-------ELEVAEDRVKSGDAKISELEE 195
+ + ++ +L + K ++ + +ED E ++ EDR+ ++E EE
Sbjct: 954 EEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEE 1013
Query: 196 ELK 198
+ K
Sbjct: 1014 KSK 1016
Score = 31.9 bits (69), Expect = 2.6
Identities = 20/103 (19%), Positives = 44/103 (42%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D K+ QA + K Q D AE+ ++ + +L Q++ L
Sbjct: 1823 LDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEA 1882
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 103
+ + ++AN + +++L A+NR+V ++ L + +
Sbjct: 1883 EEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGD 1925
>CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein.
Length = 1960
Score = 66.1 bits (154), Expect = 1e-10
Identities = 52/255 (20%), Positives = 115/255 (45%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ ++L +++ ++E +L + + A ++ E L EA +
Sbjct: 1568 QFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 1627
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+ N+ + + L K + + ++L + + S +E K E + + E M QL
Sbjct: 1628 SANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQE 1687
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
+L A A + DE++ ++A + +A + + +A+I++LEEEL+ + +
Sbjct: 1688 ELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTEL 1747
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
+ +KAN ++++ + K+L+ ++ +E G K +
Sbjct: 1748 INDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEME---GTVKSK 1804
Query: 267 YKSLADEMDSTFAEL 281
YK+ +++ A+L
Sbjct: 1805 YKASITALEAKIAQL 1819
Score = 63.7 bits (148), Expect = 7e-10
Identities = 50/207 (24%), Positives = 108/207 (52%), Gaps = 23/207 (11%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ ++ ++ E + + + + ANL+ +++N ++ L++ AQ E+ + +
Sbjct: 1727 LEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLN-LERSHAQKNENA---RQQ 1782
Query: 64 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLE-KSEERSGTAQQ------ 111
LE+ NK+L+ K +++ T +A + AL K+ Q+EE L+ +++ER +Q
Sbjct: 1783 LERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEK 1842
Query: 112 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
KL + D+ R + +++A + R+ QL QL+EA A+ A+ ++ R+L
Sbjct: 1843 KLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQREL-- 1900
Query: 172 VEDELEVAEDRVKSGDAKISELEEELK 198
ED E A+ + + ++S L+ +L+
Sbjct: 1901 -EDATETAD----AMNREVSSLKNKLR 1922
Score = 61.7 bits (143), Expect = 3e-09
Identities = 59/252 (23%), Positives = 106/252 (42%), Gaps = 7/252 (2%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E Q +D ++ N + L KL QVE++ + +LE+ + EKQ+ A+V
Sbjct: 1307 ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQV 1366
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
A + +K++ LE +EE Q+ L Q +E LE + ++ +D L
Sbjct: 1367 ADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLL 1426
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
L R A + + K + + LA E++ A+ + A+ E+E K +
Sbjct: 1427 VDLDHQRQSACNLEKKQKKFDQLLA--EEKTISAKYAEERDRAEAEAREKETKAL----- 1479
Query: 206 SLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKD 265
SL + E+A ++ E K+V +L+K LE ++ K
Sbjct: 1480 SLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKT 1539
Query: 266 RYKSLADEMDST 277
+ + L DE+ +T
Sbjct: 1540 QLEELEDELQAT 1551
Score = 55.2 bits (127), Expect = 2e-07
Identities = 45/224 (20%), Positives = 97/224 (43%), Gaps = 7/224 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M +++++ A + K A + D + +++ + EE R L+ ++AQ+EE+L
Sbjct: 1682 MIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEE 1741
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ E N L++ Q+ ++ Q+ E ++ E ++ + KL E + +
Sbjct: 1742 QGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTV 1801
Query: 121 DENNR-MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+ LE + Q EE++D N+ KE + + ++ L V+DE A
Sbjct: 1802 KSKYKASITALEAKIAQLEEQLD---NETKERQAACKQVRRTEKKLKDVLLQVDDERRNA 1858
Query: 180 E---DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
E D+ ++ +L+ +L+ + S K + +E+
Sbjct: 1859 EQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELED 1902
Score = 54.8 bits (126), Expect = 3e-07
Identities = 56/254 (22%), Positives = 109/254 (42%), Gaps = 13/254 (5%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 73
E+D A +A E +A E+ E+ EL++ Q ++ + + K + E
Sbjct: 1463 ERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHE 1522
Query: 74 KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
EK A E +V + +++++E++L+ +E+ + L+A ++ E + L+ R
Sbjct: 1523 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVN-LQAMKAQFERD-----LQGR 1576
Query: 134 AQQDEERMDQLTNQLKEARL-LAEDADGKSDEVS--RKLAFVEDELEVAEDRV-KSGDAK 189
+Q EE+ QL Q++E L ++ +S V+ +KL +LE D K+ D
Sbjct: 1577 DEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEA 1636
Query: 190 ISE---LEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTV 246
I + L+ ++K L S E+ + +E +
Sbjct: 1637 IKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAK 1696
Query: 247 KKLQKEVDRLEDEL 260
++ Q+E D L DE+
Sbjct: 1697 RQAQQERDELADEI 1710
Score = 53.6 bits (123), Expect = 8e-07
Identities = 56/236 (23%), Positives = 111/236 (47%), Gaps = 30/236 (12%)
Query: 3 AIKKKMQAMK-LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
A K + +A+K L K A K C ++ D E++ + +E +KKL +E ++I +
Sbjct: 1629 ANKNRDEAIKQLRKLQAQMK--DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQ 1686
Query: 62 NKL---EQANKDLEEKEKQLTATEA-----------EVAALNRKVQQIEEDLEKSEERSG 107
+L E+A + +++ +L A E L ++ Q+EE+LE+ + +
Sbjct: 1687 EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTE 1746
Query: 108 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG--KS--- 162
+L +A D+ N + + AQ++E QL Q KE ++ ++ +G KS
Sbjct: 1747 LINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYK 1806
Query: 163 ---DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
+ K+A +E++L+ ++ ++ E++LK V L+V +E+ N
Sbjct: 1807 ASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDV-----LLQVDDERRN 1857
Score = 53.2 bits (122), Expect = 1e-06
Identities = 55/274 (20%), Positives = 116/274 (42%), Gaps = 15/274 (5%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN-- 62
+++ Q ++ EK E+Q + +K+ E + KL ++EE+ I+ ++
Sbjct: 928 EERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQN 987
Query: 63 -KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
KL + K LE++ + T E ++ + +++ K E +++L ++
Sbjct: 988 CKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLK---NKHEAMITDLEERLRREEKQRQ 1044
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAEDADGKSDEVSRKLAFVEDELEVAE 180
E + + LE + +++ +L Q+ E ++ LA+ K +E+ LA VE+E
Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAK----KEEELQAALARVEEEAAQKN 1100
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+K KI ELE ++ + L+S S KA ++ +
Sbjct: 1101 MALK----KIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA 1156
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
+ K ++EV+ L+ L +++ EM
Sbjct: 1157 AQQELRSKREQEVNILKKTLEEEAKTHEAQIQEM 1190
Score = 50.4 bits (115), Expect = 7e-06
Identities = 43/214 (20%), Positives = 98/214 (45%), Gaps = 4/214 (1%)
Query: 9 QAMKLEKDNAMDKA--DTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
Q +L++D ++A + E+Q RD E + E+ + A +E + ++
Sbjct: 1112 QISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNI 1171
Query: 67 ANKDLEEKEKQLTATEAEVAALNRK-VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
K LEE+ K A E+ + + V+++ E LE+++ ++ + E
Sbjct: 1172 LKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELAN 1231
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
KVL E + ++ QL+E ++ + + E++ K+ ++ EL+ +
Sbjct: 1232 EVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQ 1291
Query: 186 GDAKISELEEELKVVGNSLK-SLEVSEEKANQRV 218
D+K S+L ++ + + L+ + E+ +E+ Q++
Sbjct: 1292 SDSKSSKLTKDFSALESQLQDTQELLQEENRQKL 1325
Score = 49.6 bits (113), Expect = 1e-05
Identities = 45/189 (23%), Positives = 90/189 (47%), Gaps = 6/189 (3%)
Query: 36 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT--EAEVAALNRKVQ 93
AE+V ++++ + L+Q E+ + +KLE+ L+++ L +A N + +
Sbjct: 1383 AEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKK 1442
Query: 94 QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQ---LTNQLKE 150
Q + D +EE++ +A+ + A+ + K L + A+ EE M+Q L K+
Sbjct: 1443 QKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKAL-SLARALEEAMEQKAELERLNKQ 1501
Query: 151 ARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVS 210
R ED D+V + + +E E +V+ ++ ELE+EL+ ++ LEV+
Sbjct: 1502 FRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVN 1561
Query: 211 EEKANQRVE 219
+ + E
Sbjct: 1562 LQAMKAQFE 1570
Score = 48.4 bits (110), Expect = 3e-05
Identities = 44/228 (19%), Positives = 96/228 (42%), Gaps = 8/228 (3%)
Query: 49 KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 108
++++ EE+++ + +L + + E +LT E + L + Q++E L+ E
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAE 898
Query: 109 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
A++ E +C LE R +++EER L + K+ + ++ + + +E
Sbjct: 899 AEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEES- 957
Query: 169 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXX 228
+L++ ++V + +AK+ +LEEE ++ + L ++ R+ EF
Sbjct: 958 ---ARQKLQL--EKVTT-EAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE 1011
Query: 229 XXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE-LGINKDRYKSLADEMD 275
+ L++ + R E + + K R K D D
Sbjct: 1012 EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTD 1059
Score = 48.4 bits (110), Expect = 3e-05
Identities = 61/275 (22%), Positives = 113/275 (41%), Gaps = 14/275 (5%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
K++ +L +N + + +T + Q L+ ++ + EL + ++ L K +LE+
Sbjct: 856 KVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEE 915
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
DLE + ++ + A +K+QQ ++LE+ E +A+QKL Q
Sbjct: 916 ICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKL---QLEKVTTEAK 972
Query: 127 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
K LE ++ DQ KE +LL ED + E + L E++ +
Sbjct: 973 LKKLE---EEQIILEDQNCKLAKEKKLL-ED---RIAEFTTNLTEEEEKSKSLAKLKNKH 1025
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTV 246
+A I++LEE L+ + LE + K + K
Sbjct: 1026 EAMITDLEERLRREEKQRQELEKTRRKLE---GDSTDLSDQIAELQAQIAELKMQLAKKE 1082
Query: 247 KKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++LQ + R+E+E K + E++S +EL
Sbjct: 1083 EELQAALARVEEEAAQKNMALKKIR-ELESQISEL 1116
Score = 48.4 bits (110), Expect = 3e-05
Identities = 46/231 (19%), Positives = 105/231 (45%), Gaps = 13/231 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ + + + KLE++ + + C+ A++ L +++ E L ++ + + L
Sbjct: 964 LEKVTTEAKLKKLEEEQIILEDQNCKL-AKEKKLLEDRIAEFTTNLTEE-EEKSKSLAKL 1021
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK--SEERSGTAQQKLLEAQQ 118
KNK E DLEE+ ++ E+ RK++ DL +E ++ A+ K+ A++
Sbjct: 1022 KNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKK 1081
Query: 119 SADENNRMCKVLENRAQQD---------EERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
+ + +V E AQ++ E ++ +L L+ R A+ + ++ +L
Sbjct: 1082 EEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEEL 1141
Query: 170 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
++ ELE D + S+ E+E+ ++ +L+ + E Q + +
Sbjct: 1142 EALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQ 1192
Score = 47.6 bits (108), Expect = 5e-05
Identities = 51/220 (23%), Positives = 101/220 (45%), Gaps = 21/220 (9%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE----KVNEEVRELQKKLAQVEEDLIL 59
+K K +AM + + + + + Q+ + E +++++ ELQ ++A+++ L
Sbjct: 1021 LKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAK 1080
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
+ +L+ A +EE+ Q ++ L ++ +++EDLE SE S +K Q
Sbjct: 1081 KEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLE-SERASRNKAEK-----QK 1134
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
D + + LE + E+ +D Q +E R E EV+ +E+E +
Sbjct: 1135 RD----LGEELEALKTELEDTLDSTAAQ-QELRSKREQ------EVNILKKTLEEEAKTH 1183
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
E +++ K S+ EEL K ++ + EKA Q +E
Sbjct: 1184 EAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLE 1223
Score = 46.8 bits (106), Expect = 9e-05
Identities = 42/184 (22%), Positives = 86/184 (46%), Gaps = 8/184 (4%)
Query: 41 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 100
++V +LQ +L V L + +K + KD E QL T+ + NR+ + L+
Sbjct: 1273 DKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLK 1332
Query: 101 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA----RLLAE 156
+ E+ + +++L E +++ + L + +++M+ L+ A R L +
Sbjct: 1333 QVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQK 1392
Query: 157 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
D +G S K+A D+LE + R++ ++ +L +L S +LE ++K +Q
Sbjct: 1393 DLEGLSQRHEEKVA-AYDKLEKTKTRLQQ---ELDDLLVDLDHQRQSACNLEKKQKKFDQ 1448
Query: 217 RVEE 220
+ E
Sbjct: 1449 LLAE 1452
Score = 46.0 bits (104), Expect = 2e-04
Identities = 33/150 (22%), Positives = 67/150 (44%), Gaps = 4/150 (2%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A K + +LE+ N K + Q + +++ K + L+ K+AQ+EE L
Sbjct: 1773 AQKNENARQQLERQNKELKV---KLQEMEGTVKS-KYKASITALEAKIAQLEEQLDNETK 1828
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+ + A K + EK+L +V R +Q ++ +K+ R +++L EA++ A
Sbjct: 1829 ERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQR 1888
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
N + L+ + E D + ++ +
Sbjct: 1889 ANASRRKLQRELEDATETADAMNREVSSLK 1918
Score = 42.7 bits (96), Expect = 0.001
Identities = 48/220 (21%), Positives = 95/220 (43%), Gaps = 7/220 (3%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
+Q +K + K E + + E+ E L+K++A + + K K+E +
Sbjct: 1317 LQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDS 1376
Query: 68 NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD-ENNRM 126
LE E+ + ++ L+++ ++ +K E+ QQ+L + D +
Sbjct: 1377 VGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSA 1436
Query: 127 CKVLENRAQQDEERMDQLTNQLKEA----RLLAEDADGKSDEVSRKLAFVEDELEVAE-D 181
C + + + + D+ ++ T K A R AE + ++ +S A E + AE +
Sbjct: 1437 CNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELE 1496
Query: 182 RV-KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
R+ K ++ +L VG S+ LE S+ Q+VEE
Sbjct: 1497 RLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEE 1536
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/138 (23%), Positives = 68/138 (49%), Gaps = 5/138 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K K+Q M+ + KA +A+ A L E+++ E +E Q QV K+
Sbjct: 1790 LKVKLQEMEGTVKSKY-KASITALEAKIAQLE-EQLDNETKERQAACKQVRRTEKKLKDV 1847
Query: 64 LEQAN---KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
L Q + ++ E+ + Q + L R++++ EE+ +++ Q++L +A ++A
Sbjct: 1848 LLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETA 1907
Query: 121 DENNRMCKVLENRAQQDE 138
D NR L+N+ ++ +
Sbjct: 1908 DAMNREVSSLKNKLRRGD 1925
Score = 40.3 bits (90), Expect = 0.007
Identities = 41/225 (18%), Positives = 98/225 (43%), Gaps = 9/225 (4%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ K++ ++ EK++ ++ + E+ + + ++ +V +++KK+ L +
Sbjct: 1326 SLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEE 1385
Query: 63 KLEQANKDLE----EKEKQLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLE 115
+ KDLE E+++ A + R Q++++ DL+ + + ++K +
Sbjct: 1386 VKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKK 1445
Query: 116 AQQ-SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
Q A+E K E R + + E ++ T L AR L E + K+ E+ R
Sbjct: 1446 FDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKA-ELERLNKQFRT 1504
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
E+E + ELE+ + + ++ ++ E+ ++
Sbjct: 1505 EMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQ 1549
Score = 39.9 bits (89), Expect = 0.010
Identities = 46/223 (20%), Positives = 97/223 (43%), Gaps = 13/223 (5%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ---VEEDLI-- 58
++K Q ++ E+ ++ Q D+ + +KV +++ELQ K + V +L
Sbjct: 1215 LEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADK 1274
Query: 59 LNKNKLEQANKD--LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+ K ++E N L + + + + + +AL ++Q +E L++ + + KL +
Sbjct: 1275 VTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQV 1334
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG---KSDEVSRKLAFVE 173
+ + + E E+++ L Q+ + + ED+ G ++EV RKL +
Sbjct: 1335 EDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKL---Q 1391
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
+LE R + A +LE+ + L L V + Q
Sbjct: 1392 KDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQ 1434
Score = 33.1 bits (72), Expect = 1.1
Identities = 35/183 (19%), Positives = 82/183 (44%), Gaps = 22/183 (12%)
Query: 34 LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 93
L+ + EE+ +++L +V E + +N+L + +E + QL A + ++ +
Sbjct: 838 LQVSRQEEEMMAKEEELVKVREKQLAAENRLTE----METLQSQLMAEKLQLQEQLQAET 893
Query: 94 QIEEDLEKSEERSGTAQQKLLEA----QQSADENNRMC-------KVLENRAQQDEERMD 142
++ + E+ R +Q+L E + +E C K ++ Q+ EE+++
Sbjct: 894 ELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLE 953
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVED-------ELEVAEDRVKSGDAKISELEE 195
+ + ++ +L + K ++ + +ED E ++ EDR+ ++E EE
Sbjct: 954 EEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEE 1013
Query: 196 ELK 198
+ K
Sbjct: 1014 KSK 1016
Score = 31.9 bits (69), Expect = 2.6
Identities = 20/103 (19%), Positives = 44/103 (42%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D K+ QA + K Q D AE+ ++ + +L Q++ L
Sbjct: 1823 LDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEA 1882
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 103
+ + ++AN + +++L A+NR+V ++ L + +
Sbjct: 1883 EEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGD 1925
>AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein
protein.
Length = 1331
Score = 66.1 bits (154), Expect = 1e-10
Identities = 52/255 (20%), Positives = 115/255 (45%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ ++L +++ ++E +L + + A ++ E L EA +
Sbjct: 990 QFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 1049
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+ N+ + + L K + + ++L + + S +E K E + + E M QL
Sbjct: 1050 SANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQE 1109
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
+L A A + DE++ ++A + +A + + +A+I++LEEEL+ + +
Sbjct: 1110 ELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTEL 1169
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
+ +KAN ++++ + K+L+ ++ +E G K +
Sbjct: 1170 INDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEME---GTVKSK 1226
Query: 267 YKSLADEMDSTFAEL 281
YK+ +++ A+L
Sbjct: 1227 YKASITALEAKIAQL 1241
Score = 57.2 bits (132), Expect = 6e-08
Identities = 41/167 (24%), Positives = 87/167 (52%), Gaps = 16/167 (9%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ ++ ++ E + + + + ANL+ +++N ++ L++ AQ E+ + +
Sbjct: 1149 LEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLN-LERSHAQKNENA---RQQ 1204
Query: 64 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLE-KSEERSGTAQQ------ 111
LE+ NK+L+ K +++ T +A + AL K+ Q+EE L+ +++ER +Q
Sbjct: 1205 LERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEK 1264
Query: 112 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA 158
KL + D+ R + +++A + R+ QL QL+EA A+ A
Sbjct: 1265 KLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRA 1311
Score = 53.6 bits (123), Expect = 8e-07
Identities = 55/219 (25%), Positives = 104/219 (47%), Gaps = 24/219 (10%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ A KKKMQ E + +++ ++ Q+ L+ EKV E + KKL + +DL+++
Sbjct: 798 LQAEKKKMQQNIQELEEQLEEEESARQK-----LQLEKVTTEAK--LKKLEEELDDLLVD 850
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ Q+ +LE+K+K+ AE ++ K E D ++E R + K L ++
Sbjct: 851 LDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAG-ERDRAEAEARE--KETKALSLARAL 907
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+E +E +A+ ER++ K+ R ED D+V + + +E E
Sbjct: 908 EE------AMEQKAEL--ERLN------KQFRTEMEDLMSSKDDVGKSVHELEKSKRALE 953
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+V+ ++ ELE EL+ ++ LEV+ + + E
Sbjct: 954 QQVEEMKTQLEELEGELQATEDAKLRLEVNLQAMKAQFE 992
Score = 53.6 bits (123), Expect = 8e-07
Identities = 56/236 (23%), Positives = 111/236 (47%), Gaps = 30/236 (12%)
Query: 3 AIKKKMQAMK-LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
A K + +A+K L K A K C ++ D E++ + +E +KKL +E ++I +
Sbjct: 1051 ANKNRDEAIKQLRKLQAQMK--DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQ 1108
Query: 62 NKL---EQANKDLEEKEKQLTATEA-----------EVAALNRKVQQIEEDLEKSEERSG 107
+L E+A + +++ +L A E L ++ Q+EE+LE+ + +
Sbjct: 1109 EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTE 1168
Query: 108 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG--KS--- 162
+L +A D+ N + + AQ++E QL Q KE ++ ++ +G KS
Sbjct: 1169 LINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYK 1228
Query: 163 ---DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
+ K+A +E++L+ ++ ++ E++LK V L+V +E+ N
Sbjct: 1229 ASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDV-----LLQVDDERRN 1279
Score = 51.6 bits (118), Expect = 3e-06
Identities = 55/261 (21%), Positives = 112/261 (42%), Gaps = 7/261 (2%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
K++ +L +N + + +T + Q L+ ++ + EL + ++ L K +LE+
Sbjct: 720 KVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEE 779
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL-LEAQQSADENNR 125
DLE + ++ + A +K+QQ ++LE+ E +A+QKL LE + + +
Sbjct: 780 ICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKK 839
Query: 126 MCKVLEN-RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
+ + L++ D +R + K+ + A+ K+ +S K A D E AE R K
Sbjct: 840 LEEELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKT--ISAKYAGERDRAE-AEAREK 896
Query: 185 SGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXK 244
+ K L L+ LE ++ +E+ +
Sbjct: 897 --ETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQ 954
Query: 245 TVKKLQKEVDRLEDELGINKD 265
V++++ +++ LE EL +D
Sbjct: 955 QVEEMKTQLEELEGELQATED 975
Score = 50.8 bits (116), Expect = 5e-06
Identities = 57/297 (19%), Positives = 117/297 (39%), Gaps = 17/297 (5%)
Query: 2 DAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
+A +K+ +A+ L + + AM++ E+ + E + ++ K + ++E+
Sbjct: 892 EAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRA 951
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGTAQQKL-- 113
+ ++E+ LEE E +L ATE L +Q Q E DL+ +E+S +++L
Sbjct: 952 LEQQVEEMKTQLEELEGELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVR 1011
Query: 114 ----LEAQQSADENNRMC-----KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 164
+EA+ + R K LE + E +D EA + +
Sbjct: 1012 QVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKD 1071
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXX 224
R+L E + K + K+ +E E+ + L + E ++ +A Q +E
Sbjct: 1072 CMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADE 1131
Query: 225 XXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ +L++E++ + + DR K ++D +L
Sbjct: 1132 IANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDL 1188
Score = 50.8 bits (116), Expect = 5e-06
Identities = 42/202 (20%), Positives = 90/202 (44%), Gaps = 7/202 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M +++++ A + K A + D + +++ + EE R L+ ++AQ+EE+L
Sbjct: 1104 MIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEE 1163
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ E N L++ Q+ ++ Q+ E ++ E ++ + KL E + +
Sbjct: 1164 QGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTV 1223
Query: 121 DENNR-MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+ LE + Q EE++D N+ KE + + ++ L V+DE A
Sbjct: 1224 KSKYKASITALEAKIAQLEEQLD---NETKERQAACKQVRRTEKKLKDVLLQVDDERRNA 1280
Query: 180 E---DRVKSGDAKISELEEELK 198
E D+ ++ +L+ +L+
Sbjct: 1281 EQYKDQADKASTRLKQLKRQLE 1302
Score = 49.6 bits (113), Expect = 1e-05
Identities = 56/271 (20%), Positives = 115/271 (42%), Gaps = 24/271 (8%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 73
E+D A +A E +A E+ E+ EL++ Q ++ + + K + E
Sbjct: 885 ERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHE 944
Query: 74 KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
EK A E +V + +++++E +L+ +E+ + L +A ++ E + L+ R
Sbjct: 945 LEKSKRALEQQVEEMKTQLEELEGELQATEDAKLRLEVNL-QAMKAQFERD-----LQGR 998
Query: 134 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISEL 193
+Q EE+ QL Q++E ED + +E +L+ E + S + E
Sbjct: 999 DEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEA 1058
Query: 194 EEELKVVGNSLKSL--EVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQK 251
++L+ + +K E+ + +A++ EE K +K ++
Sbjct: 1059 IKQLRKLQAQMKDCMRELDDTRASR--EEILAQAKENE--------------KKLKSMEA 1102
Query: 252 EVDRLEDELGINKDRYKSLADEMDSTFAELA 282
E+ +L++EL + + E D E+A
Sbjct: 1103 EMIQLQEELAAAERAKRQAQQERDELADEIA 1133
Score = 48.8 bits (111), Expect = 2e-05
Identities = 37/180 (20%), Positives = 89/180 (49%), Gaps = 15/180 (8%)
Query: 10 AMKLEKDNAMD-KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN---KLE 65
A+ LE+ ++ + E++ + E +N+ +++ ++ Q+ DL L ++ K E
Sbjct: 1140 ALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNE 1199
Query: 66 QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA-QQKLLEAQQSADENN 124
A + LE + K+L K+Q++E ++ + S TA + K+ + ++ D
Sbjct: 1200 NARQQLERQNKELKV----------KLQEMEGTVKSKYKASITALEAKIAQLEEQLDNET 1249
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
+ + + ++ E+++ + Q+ + R AE ++D+ S +L ++ +LE AE+ +
Sbjct: 1250 KERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQ 1309
Score = 45.2 bits (102), Expect = 3e-04
Identities = 33/149 (22%), Positives = 73/149 (48%), Gaps = 7/149 (4%)
Query: 49 KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 108
++++ EE+++ + +L + + E +LT E + L + Q++E L+ E
Sbjct: 703 QVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAE 762
Query: 109 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
A++ E +C LE R +++EER L + K+ + ++ + + +E
Sbjct: 763 AEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEES- 821
Query: 169 LAFVEDELEVAEDRVKSGDAKISELEEEL 197
+L++ ++V + +AK+ +LEEEL
Sbjct: 822 ---ARQKLQL--EKVTT-EAKLKKLEEEL 844
Score = 39.1 bits (87), Expect = 0.017
Identities = 29/118 (24%), Positives = 56/118 (47%), Gaps = 4/118 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A K + +LE+ N K + Q + +++ K + L+ K+AQ+EE L
Sbjct: 1195 AQKNENARQQLERQNKELKV---KLQEMEGTVKS-KYKASITALEAKIAQLEEQLDNETK 1250
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ + A K + EK+L +V R +Q ++ +K+ R +++L EA++ A
Sbjct: 1251 ERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEA 1308
>AK131080-1|BAC85130.1| 563|Homo sapiens FLJ00279 protein protein.
Length = 563
Score = 66.1 bits (154), Expect = 1e-10
Identities = 52/255 (20%), Positives = 115/255 (45%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ ++L +++ ++E +L + + A ++ E L EA +
Sbjct: 171 QFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 230
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+ N+ + + L K + + ++L + + S +E K E + + E M QL
Sbjct: 231 SANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQE 290
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
+L A A + DE++ ++A + +A + + +A+I++LEEEL+ + +
Sbjct: 291 ELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTEL 350
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
+ +KAN ++++ + K+L+ ++ +E G K +
Sbjct: 351 INDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEME---GTVKSK 407
Query: 267 YKSLADEMDSTFAEL 281
YK+ +++ A+L
Sbjct: 408 YKASITALEAKIAQL 422
Score = 63.7 bits (148), Expect = 7e-10
Identities = 50/207 (24%), Positives = 108/207 (52%), Gaps = 23/207 (11%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ ++ ++ E + + + + ANL+ +++N ++ L++ AQ E+ + +
Sbjct: 330 LEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLN-LERSHAQKNENA---RQQ 385
Query: 64 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLE-KSEERSGTAQQ------ 111
LE+ NK+L+ K +++ T +A + AL K+ Q+EE L+ +++ER +Q
Sbjct: 386 LERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEK 445
Query: 112 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
KL + D+ R + +++A + R+ QL QL+EA A+ A+ ++ R+L
Sbjct: 446 KLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQREL-- 503
Query: 172 VEDELEVAEDRVKSGDAKISELEEELK 198
ED E A+ + + ++S L+ +L+
Sbjct: 504 -EDATETAD----AMNREVSSLKNKLR 525
Score = 55.2 bits (127), Expect = 2e-07
Identities = 45/224 (20%), Positives = 97/224 (43%), Gaps = 7/224 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M +++++ A + K A + D + +++ + EE R L+ ++AQ+EE+L
Sbjct: 285 MIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEE 344
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ E N L++ Q+ ++ Q+ E ++ E ++ + KL E + +
Sbjct: 345 QGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTV 404
Query: 121 DENNR-MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+ LE + Q EE++D N+ KE + + ++ L V+DE A
Sbjct: 405 KSKYKASITALEAKIAQLEEQLD---NETKERQAACKQVRRTEKKLKDVLLQVDDERRNA 461
Query: 180 E---DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
E D+ ++ +L+ +L+ + S K + +E+
Sbjct: 462 EQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELED 505
Score = 53.6 bits (123), Expect = 8e-07
Identities = 56/236 (23%), Positives = 111/236 (47%), Gaps = 30/236 (12%)
Query: 3 AIKKKMQAMK-LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
A K + +A+K L K A K C ++ D E++ + +E +KKL +E ++I +
Sbjct: 232 ANKNRDEAIKQLRKLQAQMK--DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQ 289
Query: 62 NKL---EQANKDLEEKEKQLTATEA-----------EVAALNRKVQQIEEDLEKSEERSG 107
+L E+A + +++ +L A E L ++ Q+EE+LE+ + +
Sbjct: 290 EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTE 349
Query: 108 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG--KS--- 162
+L +A D+ N + + AQ++E QL Q KE ++ ++ +G KS
Sbjct: 350 LINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYK 409
Query: 163 ---DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
+ K+A +E++L+ ++ ++ E++LK V L+V +E+ N
Sbjct: 410 ASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDV-----LLQVDDERRN 460
Score = 48.8 bits (111), Expect = 2e-05
Identities = 54/281 (19%), Positives = 122/281 (43%), Gaps = 21/281 (7%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
+ +M+ + KD+ E+ R + E++ ++ EL+ +L E+ + + L
Sbjct: 106 RTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNL 165
Query: 65 E----QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ Q +DL+ +++Q +E + L R+V+++E +LE +ER Q+ + A +
Sbjct: 166 QAMKAQFERDLQGRDEQ---SEEKKKQLVRQVREMEAELE--DERK---QRSMAVAARKK 217
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
E + K LE + D+ QL++ + +D + D+ + + + E
Sbjct: 218 LEMD--LKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENE 275
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
++KS +A++ +L+EE L + E ++ +A Q +E
Sbjct: 276 KKLKSMEAEMIQLQEE-------LAAAERAKRQAQQERDELADEIANSSGKGALALEEKR 328
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ +L++E++ + + DR K ++D +L
Sbjct: 329 RLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDL 369
Score = 48.4 bits (110), Expect = 3e-05
Identities = 52/243 (21%), Positives = 106/243 (43%), Gaps = 27/243 (11%)
Query: 42 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 101
E+ L K+ EDL+ +K + K + E EK A E +V + +++++E++L+
Sbjct: 97 ELERLNKQFRTEMEDLMSSK---DDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQA 153
Query: 102 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
+E+ + L +A ++ E + L+ R +Q EE+ QL Q++E ED +
Sbjct: 154 TEDAKLRLEVNL-QAMKAQFERD-----LQGRDEQSEEKKKQLVRQVREMEAELEDERKQ 207
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSL--EVSEEKANQRVE 219
+E +L+ E + S + E ++L+ + +K E+ + +A++ E
Sbjct: 208 RSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASR--E 265
Query: 220 EFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFA 279
E K +K ++ E+ +L++EL + + E D
Sbjct: 266 EILAQAKENE--------------KKLKSMEAEMIQLQEELAAAERAKRQAQQERDELAD 311
Query: 280 ELA 282
E+A
Sbjct: 312 EIA 314
Score = 46.0 bits (104), Expect = 2e-04
Identities = 33/150 (22%), Positives = 67/150 (44%), Gaps = 4/150 (2%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A K + +LE+ N K + Q + +++ K + L+ K+AQ+EE L
Sbjct: 376 AQKNENARQQLERQNKELKV---KLQEMEGTVKS-KYKASITALEAKIAQLEEQLDNETK 431
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+ + A K + EK+L +V R +Q ++ +K+ R +++L EA++ A
Sbjct: 432 ERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQR 491
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
N + L+ + E D + ++ +
Sbjct: 492 ANASRRKLQRELEDATETADAMNREVSSLK 521
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/138 (23%), Positives = 68/138 (49%), Gaps = 5/138 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K K+Q M+ + KA +A+ A L E+++ E +E Q QV K+
Sbjct: 393 LKVKLQEMEGTVKSKY-KASITALEAKIAQLE-EQLDNETKERQAACKQVRRTEKKLKDV 450
Query: 64 LEQAN---KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
L Q + ++ E+ + Q + L R++++ EE+ +++ Q++L +A ++A
Sbjct: 451 LLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETA 510
Query: 121 DENNRMCKVLENRAQQDE 138
D NR L+N+ ++ +
Sbjct: 511 DAMNREVSSLKNKLRRGD 528
Score = 33.9 bits (74), Expect = 0.65
Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Query: 138 EERMDQ---LTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 194
EE M+Q L K+ R ED D+V + + +E E +V+ ++ ELE
Sbjct: 89 EEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELE 148
Query: 195 EELKVVGNSLKSLEVSEEKANQRVE 219
+EL+ ++ LEV+ + + E
Sbjct: 149 DELQATEDAKLRLEVNLQAMKAQFE 173
Score = 31.9 bits (69), Expect = 2.6
Identities = 20/103 (19%), Positives = 44/103 (42%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D K+ QA + K Q D AE+ ++ + +L Q++ L
Sbjct: 426 LDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEA 485
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 103
+ + ++AN + +++L A+NR+V ++ L + +
Sbjct: 486 EEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGD 528
>AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy
polypeptide 9 protein.
Length = 1960
Score = 66.1 bits (154), Expect = 1e-10
Identities = 52/255 (20%), Positives = 115/255 (45%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ ++L +++ ++E +L + + A ++ E L EA +
Sbjct: 1568 QFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 1627
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+ N+ + + L K + + ++L + + S +E K E + + E M QL
Sbjct: 1628 SANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQE 1687
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
+L A A + DE++ ++A + +A + + +A+I++LEEEL+ + +
Sbjct: 1688 ELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTEL 1747
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
+ +KAN ++++ + K+L+ ++ +E G K +
Sbjct: 1748 INDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEME---GTVKSK 1804
Query: 267 YKSLADEMDSTFAEL 281
YK+ +++ A+L
Sbjct: 1805 YKASITALEAKIAQL 1819
Score = 63.7 bits (148), Expect = 7e-10
Identities = 50/207 (24%), Positives = 108/207 (52%), Gaps = 23/207 (11%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ ++ ++ E + + + + ANL+ +++N ++ L++ AQ E+ + +
Sbjct: 1727 LEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLN-LERSHAQKNENA---RQQ 1782
Query: 64 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLE-KSEERSGTAQQ------ 111
LE+ NK+L+ K +++ T +A + AL K+ Q+EE L+ +++ER +Q
Sbjct: 1783 LERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEK 1842
Query: 112 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
KL + D+ R + +++A + R+ QL QL+EA A+ A+ ++ R+L
Sbjct: 1843 KLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQREL-- 1900
Query: 172 VEDELEVAEDRVKSGDAKISELEEELK 198
ED E A+ + + ++S L+ +L+
Sbjct: 1901 -EDATETAD----AMNREVSSLKNKLR 1922
Score = 61.7 bits (143), Expect = 3e-09
Identities = 59/252 (23%), Positives = 106/252 (42%), Gaps = 7/252 (2%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E Q +D ++ N + L KL QVE++ + +LE+ + EKQ+ A+V
Sbjct: 1307 ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQV 1366
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
A + +K++ LE +EE Q+ L Q +E LE + ++ +D L
Sbjct: 1367 ADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLL 1426
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
L R A + + K + + LA E++ A+ + A+ E+E K +
Sbjct: 1427 VDLDHQRQSACNLEKKQKKFDQLLA--EEKTISAKYAEERDRAEAEAREKETKAL----- 1479
Query: 206 SLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKD 265
SL + E+A ++ E K+V +L+K LE ++ K
Sbjct: 1480 SLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKT 1539
Query: 266 RYKSLADEMDST 277
+ + L DE+ +T
Sbjct: 1540 QLEELEDELQAT 1551
Score = 55.2 bits (127), Expect = 2e-07
Identities = 45/224 (20%), Positives = 97/224 (43%), Gaps = 7/224 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M +++++ A + K A + D + +++ + EE R L+ ++AQ+EE+L
Sbjct: 1682 MIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEE 1741
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ E N L++ Q+ ++ Q+ E ++ E ++ + KL E + +
Sbjct: 1742 QGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTV 1801
Query: 121 DENNR-MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+ LE + Q EE++D N+ KE + + ++ L V+DE A
Sbjct: 1802 KSKYKASITALEAKIAQLEEQLD---NETKERQAACKQVRRTEKKLKDVLLQVDDERRNA 1858
Query: 180 E---DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
E D+ ++ +L+ +L+ + S K + +E+
Sbjct: 1859 EQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELED 1902
Score = 54.8 bits (126), Expect = 3e-07
Identities = 56/254 (22%), Positives = 109/254 (42%), Gaps = 13/254 (5%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 73
E+D A +A E +A E+ E+ EL++ Q ++ + + K + E
Sbjct: 1463 ERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHE 1522
Query: 74 KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
EK A E +V + +++++E++L+ +E+ + L+A ++ E + L+ R
Sbjct: 1523 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVN-LQAMKAQFERD-----LQGR 1576
Query: 134 AQQDEERMDQLTNQLKEARL-LAEDADGKSDEVS--RKLAFVEDELEVAEDRV-KSGDAK 189
+Q EE+ QL Q++E L ++ +S V+ +KL +LE D K+ D
Sbjct: 1577 DEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEA 1636
Query: 190 ISE---LEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTV 246
I + L+ ++K L S E+ + +E +
Sbjct: 1637 IKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAK 1696
Query: 247 KKLQKEVDRLEDEL 260
++ Q+E D L DE+
Sbjct: 1697 RQAQQERDELADEI 1710
Score = 53.6 bits (123), Expect = 8e-07
Identities = 56/236 (23%), Positives = 111/236 (47%), Gaps = 30/236 (12%)
Query: 3 AIKKKMQAMK-LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
A K + +A+K L K A K C ++ D E++ + +E +KKL +E ++I +
Sbjct: 1629 ANKNRDEAIKQLRKLQAQMK--DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQ 1686
Query: 62 NKL---EQANKDLEEKEKQLTATEA-----------EVAALNRKVQQIEEDLEKSEERSG 107
+L E+A + +++ +L A E L ++ Q+EE+LE+ + +
Sbjct: 1687 EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTE 1746
Query: 108 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG--KS--- 162
+L +A D+ N + + AQ++E QL Q KE ++ ++ +G KS
Sbjct: 1747 LINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYK 1806
Query: 163 ---DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
+ K+A +E++L+ ++ ++ E++LK V L+V +E+ N
Sbjct: 1807 ASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDV-----LLQVDDERRN 1857
Score = 53.2 bits (122), Expect = 1e-06
Identities = 55/274 (20%), Positives = 116/274 (42%), Gaps = 15/274 (5%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN-- 62
+++ Q ++ EK E+Q + +K+ E + KL ++EE+ I+ ++
Sbjct: 928 EERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQN 987
Query: 63 -KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
KL + K LE++ + T E ++ + +++ K E +++L ++
Sbjct: 988 CKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLK---NKHEAMITDLEERLRREEKQRQ 1044
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAEDADGKSDEVSRKLAFVEDELEVAE 180
E + + LE + +++ +L Q+ E ++ LA+ K +E+ LA VE+E
Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAK----KEEELQAALARVEEEAAQKN 1100
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+K KI ELE ++ + L+S S KA ++ +
Sbjct: 1101 MALK----KIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA 1156
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
+ K ++EV+ L+ L +++ EM
Sbjct: 1157 AQQELRSKREQEVNILKKTLEEEAKTHEAQIQEM 1190
Score = 50.4 bits (115), Expect = 7e-06
Identities = 43/214 (20%), Positives = 98/214 (45%), Gaps = 4/214 (1%)
Query: 9 QAMKLEKDNAMDKA--DTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
Q +L++D ++A + E+Q RD E + E+ + A +E + ++
Sbjct: 1112 QISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNI 1171
Query: 67 ANKDLEEKEKQLTATEAEVAALNRK-VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
K LEE+ K A E+ + + V+++ E LE+++ ++ + E
Sbjct: 1172 LKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELAN 1231
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
KVL E + ++ QL+E ++ + + E++ K+ ++ EL+ +
Sbjct: 1232 EVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQ 1291
Query: 186 GDAKISELEEELKVVGNSLK-SLEVSEEKANQRV 218
D+K S+L ++ + + L+ + E+ +E+ Q++
Sbjct: 1292 SDSKSSKLTKDFSALESQLQDTQELLQEENRQKL 1325
Score = 49.6 bits (113), Expect = 1e-05
Identities = 45/189 (23%), Positives = 90/189 (47%), Gaps = 6/189 (3%)
Query: 36 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT--EAEVAALNRKVQ 93
AE+V ++++ + L+Q E+ + +KLE+ L+++ L +A N + +
Sbjct: 1383 AEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKK 1442
Query: 94 QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQ---LTNQLKE 150
Q + D +EE++ +A+ + A+ + K L + A+ EE M+Q L K+
Sbjct: 1443 QKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKAL-SLARALEEAMEQKAELERLNKQ 1501
Query: 151 ARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVS 210
R ED D+V + + +E E +V+ ++ ELE+EL+ ++ LEV+
Sbjct: 1502 FRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVN 1561
Query: 211 EEKANQRVE 219
+ + E
Sbjct: 1562 LQAMKAQFE 1570
Score = 48.4 bits (110), Expect = 3e-05
Identities = 44/228 (19%), Positives = 96/228 (42%), Gaps = 8/228 (3%)
Query: 49 KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 108
++++ EE+++ + +L + + E +LT E + L + Q++E L+ E
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAE 898
Query: 109 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
A++ E +C LE R +++EER L + K+ + ++ + + +E
Sbjct: 899 AEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEES- 957
Query: 169 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXX 228
+L++ ++V + +AK+ +LEEE ++ + L ++ R+ EF
Sbjct: 958 ---ARQKLQL--EKVTT-EAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE 1011
Query: 229 XXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE-LGINKDRYKSLADEMD 275
+ L++ + R E + + K R K D D
Sbjct: 1012 EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTD 1059
Score = 48.4 bits (110), Expect = 3e-05
Identities = 61/275 (22%), Positives = 113/275 (41%), Gaps = 14/275 (5%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
K++ +L +N + + +T + Q L+ ++ + EL + ++ L K +LE+
Sbjct: 856 KVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEE 915
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
DLE + ++ + A +K+QQ ++LE+ E +A+QKL Q
Sbjct: 916 ICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKL---QLEKVTTEAK 972
Query: 127 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
K LE ++ DQ KE +LL ED + E + L E++ +
Sbjct: 973 LKKLE---EEQIILEDQNCKLAKEKKLL-ED---RIAEFTTNLTEEEEKSKSLAKLKNKH 1025
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTV 246
+A I++LEE L+ + LE + K + K
Sbjct: 1026 EAMITDLEERLRREEKQRQELEKTRRKLE---GDSTDLSDQIAELQAQIAELKMQLAKKE 1082
Query: 247 KKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++LQ + R+E+E K + E++S +EL
Sbjct: 1083 EELQAALARVEEEAAQKNMALKKIR-ELESQISEL 1116
Score = 48.4 bits (110), Expect = 3e-05
Identities = 46/231 (19%), Positives = 105/231 (45%), Gaps = 13/231 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ + + + KLE++ + + C+ A++ L +++ E L ++ + + L
Sbjct: 964 LEKVTTEAKLKKLEEEQIILEDQNCKL-AKEKKLLEDRIAEFTTNLTEE-EEKSKSLAKL 1021
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK--SEERSGTAQQKLLEAQQ 118
KNK E DLEE+ ++ E+ RK++ DL +E ++ A+ K+ A++
Sbjct: 1022 KNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKK 1081
Query: 119 SADENNRMCKVLENRAQQD---------EERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
+ + +V E AQ++ E ++ +L L+ R A+ + ++ +L
Sbjct: 1082 EEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEEL 1141
Query: 170 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
++ ELE D + S+ E+E+ ++ +L+ + E Q + +
Sbjct: 1142 EALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQ 1192
Score = 47.6 bits (108), Expect = 5e-05
Identities = 51/220 (23%), Positives = 101/220 (45%), Gaps = 21/220 (9%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE----KVNEEVRELQKKLAQVEEDLIL 59
+K K +AM + + + + + Q+ + E +++++ ELQ ++A+++ L
Sbjct: 1021 LKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAK 1080
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
+ +L+ A +EE+ Q ++ L ++ +++EDLE SE S +K Q
Sbjct: 1081 KEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLE-SERASRNKAEK-----QK 1134
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
D + + LE + E+ +D Q +E R E EV+ +E+E +
Sbjct: 1135 RD----LGEELEALKTELEDTLDSTAAQ-QELRSKREQ------EVNILKKTLEEEAKTH 1183
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
E +++ K S+ EEL K ++ + EKA Q +E
Sbjct: 1184 EAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLE 1223
Score = 46.8 bits (106), Expect = 9e-05
Identities = 42/184 (22%), Positives = 86/184 (46%), Gaps = 8/184 (4%)
Query: 41 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 100
++V +LQ +L V L + +K + KD E QL T+ + NR+ + L+
Sbjct: 1273 DKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLK 1332
Query: 101 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA----RLLAE 156
+ E+ + +++L E +++ + L + +++M+ L+ A R L +
Sbjct: 1333 QVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQK 1392
Query: 157 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
D +G S K+A D+LE + R++ ++ +L +L S +LE ++K +Q
Sbjct: 1393 DLEGLSQRHEEKVA-AYDKLEKTKTRLQQ---ELDDLLVDLDHQRQSACNLEKKQKKFDQ 1448
Query: 217 RVEE 220
+ E
Sbjct: 1449 LLAE 1452
Score = 46.0 bits (104), Expect = 2e-04
Identities = 33/150 (22%), Positives = 67/150 (44%), Gaps = 4/150 (2%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A K + +LE+ N K + Q + +++ K + L+ K+AQ+EE L
Sbjct: 1773 AQKNENARQQLERQNKELKV---KLQEMEGTVKS-KYKASITALEAKIAQLEEQLDNETK 1828
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+ + A K + EK+L +V R +Q ++ +K+ R +++L EA++ A
Sbjct: 1829 ERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQR 1888
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
N + L+ + E D + ++ +
Sbjct: 1889 ANASRRKLQRELEDATETADAMNREVSSLK 1918
Score = 42.7 bits (96), Expect = 0.001
Identities = 48/220 (21%), Positives = 95/220 (43%), Gaps = 7/220 (3%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
+Q +K + K E + + E+ E L+K++A + + K K+E +
Sbjct: 1317 LQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDS 1376
Query: 68 NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD-ENNRM 126
LE E+ + ++ L+++ ++ +K E+ QQ+L + D +
Sbjct: 1377 VGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSA 1436
Query: 127 CKVLENRAQQDEERMDQLTNQLKEA----RLLAEDADGKSDEVSRKLAFVEDELEVAE-D 181
C + + + + D+ ++ T K A R AE + ++ +S A E + AE +
Sbjct: 1437 CNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELE 1496
Query: 182 RV-KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
R+ K ++ +L VG S+ LE S+ Q+VEE
Sbjct: 1497 RLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEE 1536
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/138 (23%), Positives = 68/138 (49%), Gaps = 5/138 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K K+Q M+ + KA +A+ A L E+++ E +E Q QV K+
Sbjct: 1790 LKVKLQEMEGTVKSKY-KASITALEAKIAQLE-EQLDNETKERQAACKQVRRTEKKLKDV 1847
Query: 64 LEQAN---KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
L Q + ++ E+ + Q + L R++++ EE+ +++ Q++L +A ++A
Sbjct: 1848 LLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETA 1907
Query: 121 DENNRMCKVLENRAQQDE 138
D NR L+N+ ++ +
Sbjct: 1908 DAMNREVSSLKNKLRRGD 1925
Score = 40.3 bits (90), Expect = 0.007
Identities = 41/225 (18%), Positives = 98/225 (43%), Gaps = 9/225 (4%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ K++ ++ EK++ ++ + E+ + + ++ +V +++KK+ L +
Sbjct: 1326 SLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEE 1385
Query: 63 KLEQANKDLE----EKEKQLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLE 115
+ KDLE E+++ A + R Q++++ DL+ + + ++K +
Sbjct: 1386 VKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKK 1445
Query: 116 AQQ-SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
Q A+E K E R + + E ++ T L AR L E + K+ E+ R
Sbjct: 1446 FDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKA-ELERLNKQFRT 1504
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
E+E + ELE+ + + ++ ++ E+ ++
Sbjct: 1505 EMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQ 1549
Score = 39.9 bits (89), Expect = 0.010
Identities = 46/223 (20%), Positives = 97/223 (43%), Gaps = 13/223 (5%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ---VEEDLI-- 58
++K Q ++ E+ ++ Q D+ + +KV +++ELQ K + V +L
Sbjct: 1215 LEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADK 1274
Query: 59 LNKNKLEQANKD--LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+ K ++E N L + + + + + +AL ++Q +E L++ + + KL +
Sbjct: 1275 VTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQV 1334
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG---KSDEVSRKLAFVE 173
+ + + E E+++ L Q+ + + ED+ G ++EV RKL +
Sbjct: 1335 EDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKL---Q 1391
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
+LE R + A +LE+ + L L V + Q
Sbjct: 1392 KDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQ 1434
Score = 33.1 bits (72), Expect = 1.1
Identities = 35/183 (19%), Positives = 82/183 (44%), Gaps = 22/183 (12%)
Query: 34 LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 93
L+ + EE+ +++L +V E + +N+L + +E + QL A + ++ +
Sbjct: 838 LQVSRQEEEMMAKEEELVKVREKQLAAENRLTE----METLQSQLMAEKLQLQEQLQAET 893
Query: 94 QIEEDLEKSEERSGTAQQKLLEA----QQSADENNRMC-------KVLENRAQQDEERMD 142
++ + E+ R +Q+L E + +E C K ++ Q+ EE+++
Sbjct: 894 ELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLE 953
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVED-------ELEVAEDRVKSGDAKISELEE 195
+ + ++ +L + K ++ + +ED E ++ EDR+ ++E EE
Sbjct: 954 EEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEE 1013
Query: 196 ELK 198
+ K
Sbjct: 1014 KSK 1016
Score = 31.9 bits (69), Expect = 2.6
Identities = 20/103 (19%), Positives = 44/103 (42%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D K+ QA + K Q D AE+ ++ + +L Q++ L
Sbjct: 1823 LDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEA 1882
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 103
+ + ++AN + +++L A+NR+V ++ L + +
Sbjct: 1883 EEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGD 1925
>M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle
myosin heavy chain (NMHC) mRNA, 3' end. ).
Length = 1247
Score = 65.7 bits (153), Expect = 2e-10
Identities = 52/255 (20%), Positives = 115/255 (45%), Gaps = 3/255 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q RD R E+ E+ ++L +++ ++E +L + + A ++ E L EA +
Sbjct: 855 QFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 914
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+ N+ + + L K + + ++L + + S +E K E + + E M QL
Sbjct: 915 SANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQE 974
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
+L A A + DE++ ++A + +A + + +A+I++LEEEL+ + +
Sbjct: 975 ELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTEL 1034
Query: 207 LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
+ +KAN ++++ + K+L+ ++ +E G K +
Sbjct: 1035 INDRLKKANLQIDQINADLNLERGHAQKNENARQQLERQNKELKVKLQEME---GTVKSK 1091
Query: 267 YKSLADEMDSTFAEL 281
YK+ +++ A+L
Sbjct: 1092 YKASITALEAKIAQL 1106
Score = 62.9 bits (146), Expect = 1e-09
Identities = 50/207 (24%), Positives = 108/207 (52%), Gaps = 23/207 (11%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ ++ ++ E + + + + ANL+ +++N ++ L++ AQ E+ + +
Sbjct: 1014 LEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINADLN-LERGHAQKNENA---RQQ 1069
Query: 64 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLE-KSEERSGTAQQ------ 111
LE+ NK+L+ K +++ T +A + AL K+ Q+EE L+ +++ER +Q
Sbjct: 1070 LERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEK 1129
Query: 112 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
KL + D+ R + +++A + R+ QL QL+EA A+ A+ ++ R+L
Sbjct: 1130 KLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQREL-- 1187
Query: 172 VEDELEVAEDRVKSGDAKISELEEELK 198
ED E A+ + + ++S L+ +L+
Sbjct: 1188 -EDATETAD----AMNREVSSLKNKLR 1209
Score = 60.5 bits (140), Expect = 7e-09
Identities = 59/253 (23%), Positives = 108/253 (42%), Gaps = 8/253 (3%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK-EKQLTATEAE 84
E Q +D ++ N + L KL QVE++ + +LE+ ++ + EKQ+ A+
Sbjct: 593 ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEEAKHNLEKQIATLHAQ 652
Query: 85 VAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQL 144
VA + +K++ LE +EE Q+ L Q +E LE + ++ +D L
Sbjct: 653 VADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDL 712
Query: 145 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL 204
L R A + + K + + LA E++ A+ + A+ E+E K +
Sbjct: 713 LVDLDHQRQSACNLEKKQKKFDQLLA--EEKTISAKYAEERDRAEAEAREKETKAL---- 766
Query: 205 KSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINK 264
SL + E+A ++ E K+V +L+K LE ++ K
Sbjct: 767 -SLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMK 825
Query: 265 DRYKSLADEMDST 277
+ + L DE+ +T
Sbjct: 826 TQLEELEDELQAT 838
Score = 56.4 bits (130), Expect = 1e-07
Identities = 46/224 (20%), Positives = 98/224 (43%), Gaps = 7/224 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M +++++ A + K A + D + +++ + EE R L+ ++AQ+EE+L
Sbjct: 969 MIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEE 1028
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ E N L++ Q+ A++ Q+ E ++ E ++ + KL E + +
Sbjct: 1029 QGNTELINDRLKKANLQIDQINADLNLERGHAQKNENARQQLERQNKELKVKLQEMEGTV 1088
Query: 121 DENNR-MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+ LE + Q EE++D N+ KE + + ++ L V+DE A
Sbjct: 1089 KSKYKASITALEAKIAQLEEQLD---NETKERQAACKQVRRTEKKLKDVLLQVDDERRNA 1145
Query: 180 E---DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
E D+ ++ +L+ +L+ + S K + +E+
Sbjct: 1146 EQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELED 1189
Score = 54.8 bits (126), Expect = 3e-07
Identities = 56/254 (22%), Positives = 109/254 (42%), Gaps = 13/254 (5%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 73
E+D A +A E +A E+ E+ EL++ Q ++ + + K + E
Sbjct: 750 ERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHE 809
Query: 74 KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
EK A E +V + +++++E++L+ +E+ + L+A ++ E + L+ R
Sbjct: 810 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVN-LQAMKAQFERD-----LQGR 863
Query: 134 AQQDEERMDQLTNQLKEARL-LAEDADGKSDEVS--RKLAFVEDELEVAEDRV-KSGDAK 189
+Q EE+ QL Q++E L ++ +S V+ +KL +LE D K+ D
Sbjct: 864 DEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEA 923
Query: 190 ISE---LEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTV 246
I + L+ ++K L S E+ + +E +
Sbjct: 924 IKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAK 983
Query: 247 KKLQKEVDRLEDEL 260
++ Q+E D L DE+
Sbjct: 984 RQAQQERDELADEI 997
Score = 53.2 bits (122), Expect = 1e-06
Identities = 55/274 (20%), Positives = 116/274 (42%), Gaps = 15/274 (5%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN-- 62
+++ Q ++ EK E+Q + +K+ E + KL ++EE+ I+ ++
Sbjct: 214 EERYQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQN 273
Query: 63 -KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
KL + K LE++ + T E ++ + +++ K E +++L ++
Sbjct: 274 CKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLK---NKHEAMITDLEERLRREEKQRQ 330
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAEDADGKSDEVSRKLAFVEDELEVAE 180
E + + LE + +++ +L Q+ E ++ LA+ K +E+ LA VE+E
Sbjct: 331 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAK----KEEELQAALARVEEEAAQKN 386
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+K KI ELE ++ + L+S S KA ++ +
Sbjct: 387 MALK----KIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA 442
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
+ K ++EV+ L+ L +++ EM
Sbjct: 443 AQQELRSKREQEVNILKKTLEEEAKTHEAQIQEM 476
Score = 52.0 bits (119), Expect = 2e-06
Identities = 43/214 (20%), Positives = 99/214 (46%), Gaps = 4/214 (1%)
Query: 9 QAMKLEKDNAMDKA--DTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
Q +L++D ++A + E+Q RD E + E+ + A +E + ++
Sbjct: 398 QISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNI 457
Query: 67 ANKDLEEKEKQLTATEAEVAALNRK-VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
K LEE+ K A E+ + + V+++ E LE+++ ++ + E
Sbjct: 458 LKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELAN 517
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
KVL + E + ++ QL+E ++ + + E++ K+ ++ EL+ +
Sbjct: 518 EVKVLLQGGRDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQ 577
Query: 186 GDAKISELEEELKVVGNSLK-SLEVSEEKANQRV 218
D+K S+L ++ + + L+ + E+ +E+ Q++
Sbjct: 578 SDSKSSKLTKDFSALESQLQDTQELLQEENRQKL 611
Score = 49.6 bits (113), Expect = 1e-05
Identities = 45/189 (23%), Positives = 90/189 (47%), Gaps = 6/189 (3%)
Query: 36 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT--EAEVAALNRKVQ 93
AE+V ++++ + L+Q E+ + +KLE+ L+++ L +A N + +
Sbjct: 670 AEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKK 729
Query: 94 QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQ---LTNQLKE 150
Q + D +EE++ +A+ + A+ + K L + A+ EE M+Q L K+
Sbjct: 730 QKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKAL-SLARALEEAMEQKAELERLNKQ 788
Query: 151 ARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVS 210
R ED D+V + + +E E +V+ ++ ELE+EL+ ++ LEV+
Sbjct: 789 FRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVN 848
Query: 211 EEKANQRVE 219
+ + E
Sbjct: 849 LQAMKAQFE 857
Score = 48.4 bits (110), Expect = 3e-05
Identities = 61/275 (22%), Positives = 113/275 (41%), Gaps = 14/275 (5%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
K++ +L +N + + +T + Q L+ ++ + EL + ++ L K +LE+
Sbjct: 142 KVREKQLAAENRLMEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEE 201
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
DLE + ++ + A +K+QQ ++LE+ E +A+QKL Q
Sbjct: 202 ICHDLEARVEEEEERYQHLQAEKKKMQQNIQELEEQLEEEESARQKL---QLEKVTTEAK 258
Query: 127 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
K LE ++ DQ KE +LL ED + E + L E++ +
Sbjct: 259 LKKLE---EEQIILEDQNCKLAKEKKLL-ED---RIAEFTTNLTEEEEKSKSLAKLKNKH 311
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTV 246
+A I++LEE L+ + LE + K + K
Sbjct: 312 EAMITDLEERLRREEKQRQELEKTRRKLE---GDSTDLSDQIAELQAQIAELKMQLAKKE 368
Query: 247 KKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++LQ + R+E+E K + E++S +EL
Sbjct: 369 EELQAALARVEEEAAQKNMALKKIR-ELESQISEL 402
Score = 48.4 bits (110), Expect = 3e-05
Identities = 46/231 (19%), Positives = 105/231 (45%), Gaps = 13/231 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ + + + KLE++ + + C+ A++ L +++ E L ++ + + L
Sbjct: 250 LEKVTTEAKLKKLEEEQIILEDQNCKL-AKEKKLLEDRIAEFTTNLTEE-EEKSKSLAKL 307
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK--SEERSGTAQQKLLEAQQ 118
KNK E DLEE+ ++ E+ RK++ DL +E ++ A+ K+ A++
Sbjct: 308 KNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKK 367
Query: 119 SADENNRMCKVLENRAQQD---------EERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
+ + +V E AQ++ E ++ +L L+ R A+ + ++ +L
Sbjct: 368 EEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEEL 427
Query: 170 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
++ ELE D + S+ E+E+ ++ +L+ + E Q + +
Sbjct: 428 EALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQ 478
Score = 47.6 bits (108), Expect = 5e-05
Identities = 51/220 (23%), Positives = 101/220 (45%), Gaps = 21/220 (9%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE----KVNEEVRELQKKLAQVEEDLIL 59
+K K +AM + + + + + Q+ + E +++++ ELQ ++A+++ L
Sbjct: 307 LKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAK 366
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
+ +L+ A +EE+ Q ++ L ++ +++EDLE SE S +K Q
Sbjct: 367 KEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLE-SERASRNKAEK-----QK 420
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
D + + LE + E+ +D Q +E R E EV+ +E+E +
Sbjct: 421 RD----LGEELEALKTELEDTLDSTAAQ-QELRSKREQ------EVNILKKTLEEEAKTH 469
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
E +++ K S+ EEL K ++ + EKA Q +E
Sbjct: 470 EAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLE 509
Score = 47.6 bits (108), Expect = 5e-05
Identities = 49/224 (21%), Positives = 102/224 (45%), Gaps = 14/224 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++K Q ++ E+ ++ Q RD+ + +KV +++ELQ K + E +K
Sbjct: 501 LEKAKQTLENERGELANEVKVLLQGGRDSEHKRKKVEAQLQELQVKFNEGERVRTELADK 560
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE-RSGTAQQKL---LEAQQS 119
+ + +L+ L+ ++++ + L + +E L+ ++E +QKL + +Q
Sbjct: 561 VTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQV 620
Query: 120 ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADG---KSDEVSRKLAFV 172
DE N + LE ++ + +++ L Q+ + + ED+ G ++EV RKL
Sbjct: 621 EDEKNSFREQLEEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKL--- 677
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
+ +LE R + A +LE+ + L L V + Q
Sbjct: 678 QKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQ 721
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/228 (18%), Positives = 95/228 (41%), Gaps = 8/228 (3%)
Query: 49 KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 108
++++ EE+++ + +L + + E +L E + L + Q++E L+ E
Sbjct: 125 QVSRQEEEMMAKEEELVKVREKQLAAENRLMEMETLQSQLMAEKLQLQEQLQAETELCAE 184
Query: 109 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
A++ E +C LE R +++EER L + K+ + ++ + + +E
Sbjct: 185 AEELRARLTAKKQELEEICHDLEARVEEEEERYQHLQAEKKKMQQNIQELEEQLEEEES- 243
Query: 169 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXX 228
+L++ ++V + +AK+ +LEEE ++ + L ++ R+ EF
Sbjct: 244 ---ARQKLQL--EKVTT-EAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE 297
Query: 229 XXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE-LGINKDRYKSLADEMD 275
+ L++ + R E + + K R K D D
Sbjct: 298 EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTD 345
Score = 46.0 bits (104), Expect = 2e-04
Identities = 33/150 (22%), Positives = 67/150 (44%), Gaps = 4/150 (2%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A K + +LE+ N K + Q + +++ K + L+ K+AQ+EE L
Sbjct: 1060 AQKNENARQQLERQNKELKV---KLQEMEGTVKS-KYKASITALEAKIAQLEEQLDNETK 1115
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+ + A K + EK+L +V R +Q ++ +K+ R +++L EA++ A
Sbjct: 1116 ERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQR 1175
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
N + L+ + E D + ++ +
Sbjct: 1176 ANASRRKLQRELEDATETADAMNREVSSLK 1205
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/240 (15%), Positives = 94/240 (39%)
Query: 21 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 80
K E+ D R E+ E + LQ + ++++++ + +LE+ ++ + +
Sbjct: 195 KKQELEEICHDLEARVEEEEERYQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVT 254
Query: 81 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 140
TEA++ L + +E+ K + + ++ E + E K L + E
Sbjct: 255 TEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAM 314
Query: 141 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 200
+ L +L+ ++ + ++ + D++ + ++ ++++ EEEL+
Sbjct: 315 ITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAA 374
Query: 201 GNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
++ + A +++ E K + L +E++ L+ EL
Sbjct: 375 LARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTEL 434
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/138 (23%), Positives = 68/138 (49%), Gaps = 5/138 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K K+Q M+ + KA +A+ A L E+++ E +E Q QV K+
Sbjct: 1077 LKVKLQEMEGTVKSKY-KASITALEAKIAQLE-EQLDNETKERQAACKQVRRTEKKLKDV 1134
Query: 64 LEQAN---KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
L Q + ++ E+ + Q + L R++++ EE+ +++ Q++L +A ++A
Sbjct: 1135 LLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETA 1194
Query: 121 DENNRMCKVLENRAQQDE 138
D NR L+N+ ++ +
Sbjct: 1195 DAMNREVSSLKNKLRRGD 1212
Score = 31.9 bits (69), Expect = 2.6
Identities = 36/183 (19%), Positives = 83/183 (45%), Gaps = 22/183 (12%)
Query: 34 LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 93
L+ + EE+ +++L +V E + +N+L ++E + QL A + ++ +
Sbjct: 124 LQVSRQEEEMMAKEEELVKVREKQLAAENRL----MEMETLQSQLMAEKLQLQEQLQAET 179
Query: 94 QIEEDLEKSEERSGTAQQKL------LEAQQSADENNRMC-----KVLENRAQQDEERMD 142
++ + E+ R +Q+L LEA+ +E K ++ Q+ EE+++
Sbjct: 180 ELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERYQHLQAEKKKMQQNIQELEEQLE 239
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVED-------ELEVAEDRVKSGDAKISELEE 195
+ + ++ +L + K ++ + +ED E ++ EDR+ ++E EE
Sbjct: 240 EEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEE 299
Query: 196 ELK 198
+ K
Sbjct: 300 KSK 302
Score = 31.9 bits (69), Expect = 2.6
Identities = 20/103 (19%), Positives = 44/103 (42%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D K+ QA + K Q D AE+ ++ + +L Q++ L
Sbjct: 1110 LDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEA 1169
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 103
+ + ++AN + +++L A+NR+V ++ L + +
Sbjct: 1170 EEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGD 1212
>X64838-1|CAA46050.1| 1427|Homo sapiens restin protein.
Length = 1427
Score = 64.1 bits (149), Expect = 5e-10
Identities = 47/213 (22%), Positives = 108/213 (50%), Gaps = 15/213 (7%)
Query: 11 MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKD 70
+K ++ +D D + + + +K+ +++ +K++ +E + +K ++
Sbjct: 755 LKATEEKLLD-LDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRE 813
Query: 71 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
L+ +E +LT + ++ +V Q++E LEK + ++K EA + A R +
Sbjct: 814 LQGRELKLTNLQENLS----EVSQVKETLEKELQ---ILKEKFAEASEEAVSVQRSMQET 866
Query: 131 ENRAQQDEERMDQLTNQLKEARLLAEDADGK---SDEVSRKLAFVEDELE--VAEDRVKS 185
N+ Q EE+ + L++ L++ R D + K DE +L +++LE +AE S
Sbjct: 867 VNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMS 926
Query: 186 GD--AKISELEEELKVVGNSLKSLEVSEEKANQ 216
GD ++++++ +EL++ ++ L++ KAN+
Sbjct: 927 GDNSSQLTKMNDELRLKERDVEELQLKLTKANE 959
Score = 60.5 bits (140), Expect = 7e-09
Identities = 44/228 (19%), Positives = 103/228 (45%), Gaps = 8/228 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A +K+++ +++EK+ KA + ++ + L+ + E + E+ + +E++L +
Sbjct: 786 LEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQIL 845
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K K +A+++ ++ + T ++ + + DLEK E + K E +
Sbjct: 846 KEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDERE 905
Query: 121 DENNRMCKVLENR----AQQDEERMDQLTNQLKEARLLAEDADG---KSDEVSRKLAFVE 173
++ + + LEN + + QLT E RL D + K + + +F++
Sbjct: 906 EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQ 965
Query: 174 DELEVAEDRVKSGDAKISEL-EEELKVVGNSLKSLEVSEEKANQRVEE 220
+E + + + ++ EEE K + L LE E ++ + +E
Sbjct: 966 KSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQE 1013
Score = 56.0 bits (129), Expect = 1e-07
Identities = 46/223 (20%), Positives = 97/223 (43%), Gaps = 14/223 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQAR----DANLRAEKVNEEVRELQK---KLAQV 53
+DA++K K E + + E+Q + + N + K + RELQ KL +
Sbjct: 765 LDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNL 824
Query: 54 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
+E+L E K+L+ +++ E ++ R +Q+ L + EE+ L
Sbjct: 825 QENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDL 884
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
+ +++ + + + R +Q + ++L N + E ++ D S +L +
Sbjct: 885 EKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDN-------SSQLTKMN 937
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
DEL + E V+ K+++ E + S++ + V E++ Q
Sbjct: 938 DELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQ 980
Score = 54.0 bits (124), Expect = 6e-07
Identities = 51/274 (18%), Positives = 113/274 (41%), Gaps = 14/274 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M+A++ K+ + EK+N+++ + +A D +L ++ + + +LQ+ +V+E +L
Sbjct: 681 MEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHL--VEMEDTLNKLQEAEIKVKELEVL- 737
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ K + K ++ QL ATE ++ ++ D + G ++ K L Q A
Sbjct: 738 QAKCNEQTKVIDNFTSQLKATEEKL---------LDLDALRKASSEGKSEMKKLRQQLEA 788
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
E + K LE + + +T +L+ L + EVS+ +E EL++ +
Sbjct: 789 AE--KQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILK 846
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
++ + ++ ++ N L E + +E+
Sbjct: 847 EKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREE 906
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
K +KL+ ++ + G N + + DE+
Sbjct: 907 QLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDEL 940
Score = 46.4 bits (105), Expect = 1e-04
Identities = 44/214 (20%), Positives = 88/214 (41%), Gaps = 7/214 (3%)
Query: 12 KLEKDNA--MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
KLE D A M + Q N +V ELQ KL + E+ + +E
Sbjct: 914 KLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTV 973
Query: 70 DLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
E+ +++ E E L RK+ +E+ +E S + + + A +++ + +
Sbjct: 974 KAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERA--TSETKTKHEE 1031
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADG--KSDEVSRKLAFVEDELEVAEDRVKSG 186
+L+N + + D+L +E L ++ + K + ++ ED +++ E K
Sbjct: 1032 ILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEK 1091
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
++ LE+ + L+ +E + VEE
Sbjct: 1092 TETLASLEDTKQTNAKLQNELDTLKENNLKNVEE 1125
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/224 (19%), Positives = 105/224 (46%), Gaps = 16/224 (7%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAE--------KVNEEVRELQKKLAQVEED 56
++ ++ ++L+ A + A ++ D ++AE K EE +EL++KL+ +E+
Sbjct: 944 ERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKK 1003
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAA-LNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ + N+ ++ E + E+ L + + E+ L+ + E + Q+L E
Sbjct: 1004 METSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEE 1063
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL-AFVED 174
++ AD+ K + A+ + M+Q+T + E ED + ++ +L E+
Sbjct: 1064 LRKQADK----AKAAQT-AEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKEN 1118
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
L+ E+ KS + E ++++ +++L+ + + +Q++
Sbjct: 1119 NLKNVEELNKSKELLTVE-NQKMEEFRKEIETLKQAAAQKSQQL 1161
Score = 44.8 bits (101), Expect = 3e-04
Identities = 44/249 (17%), Positives = 105/249 (42%), Gaps = 8/249 (3%)
Query: 42 EVRELQKKLAQVEEDLILNKNKLE-QANKDLEEKEKQLTATEAEVAALNRK----VQQIE 96
E EL+ ++ ++ D L+ Q + + K++ A A++ + ++ ++ I
Sbjct: 644 EFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIR 703
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK--EARLL 154
L+K+E++ + L Q A+ + +VL+ + + + +D T+QLK E +LL
Sbjct: 704 SKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLL 763
Query: 155 AEDADGK-SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
DA K S E ++ + +LE AE ++K + + + + + L+ E+
Sbjct: 764 DLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTN 823
Query: 214 ANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADE 273
+ + E + +Q+ + ++L ++++ L+ +
Sbjct: 824 LQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSD 883
Query: 274 MDSTFAELA 282
++ LA
Sbjct: 884 LEKLRENLA 892
Score = 42.3 bits (95), Expect = 0.002
Identities = 39/185 (21%), Positives = 85/185 (45%), Gaps = 9/185 (4%)
Query: 20 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 79
DKA Q A DA E++ +E E L ++ +N+L+ ++ + ++L
Sbjct: 1069 DKAKAA-QTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELN 1127
Query: 80 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS----ADENNRMCKVLENRAQ 135
++ + N+K+++ +++E ++ + Q+L Q+ A+E R + + +
Sbjct: 1128 KSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQK 1187
Query: 136 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 195
+EER L NQL E + +DE + A ++ + + + DA++ +L
Sbjct: 1188 LEEER-SVLNNQLLEMKKRESKFIKDADE---EKASLQKSISITSALLTEKDAELEKLRN 1243
Query: 196 ELKVV 200
E+ V+
Sbjct: 1244 EVTVL 1248
Score = 41.9 bits (94), Expect = 0.002
Identities = 42/211 (19%), Positives = 94/211 (44%), Gaps = 7/211 (3%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
M+ M EK + + +Q + + E + ++L + +E L + K+E+
Sbjct: 1084 MEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEF 1143
Query: 68 NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMC 127
K++E ++ +++AL + ++ E+L +S + T+ QKL E + +
Sbjct: 1144 RKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEV-TSHQKLEEERSVLNNQLLEM 1202
Query: 128 KVLENRAQQD-EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
K E++ +D +E L + L + D + +++ ++ + E A KS
Sbjct: 1203 KKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASA----KSL 1258
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQR 217
+ + LE + + +K+LE+ + K N+R
Sbjct: 1259 HSVVQTLESDKVKLELKVKNLEL-QLKENKR 1288
Score = 39.5 bits (88), Expect = 0.013
Identities = 47/196 (23%), Positives = 89/196 (45%), Gaps = 20/196 (10%)
Query: 35 RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 94
R E +E++ L ++ ++ K+KLE ANK E + ++++ QQ
Sbjct: 569 REETHQKEIKALYTATEKLSKENESLKSKLEHANK---ENSDVIALWKSKLETAIASHQQ 625
Query: 95 IEEDLEKSEERS-GTAQQKLLEAQQSADENNRMCK-VLEN-RAQQDEERMDQLTN-QLKE 150
E+L+ S + GT + E + ++ + +EN + QQD ER +
Sbjct: 626 AMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALR 685
Query: 151 ARLL--AEDADGKSDEVSRKLAFVED----ELEVAEDRVKSGDAKISELE-------EEL 197
A+L+ ++ + + + KL ED E+E ++++ + K+ ELE E+
Sbjct: 686 AKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQT 745
Query: 198 KVVGNSLKSLEVSEEK 213
KV+ N L+ +EEK
Sbjct: 746 KVIDNFTSQLKATEEK 761
Score = 36.3 bits (80), Expect = 0.12
Identities = 37/159 (23%), Positives = 69/159 (43%), Gaps = 14/159 (8%)
Query: 76 KQLTATEAEVAALNRKVQQIEE-----DLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
++++ T A AL K Q IE+ DLE++E T+ +E + + + VL
Sbjct: 345 RKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVL 404
Query: 131 ENRAQQDE-----ERMD----QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E A+ D+ E D +L NQL+E + ED + +E S +E + ++
Sbjct: 405 ELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHA 464
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
R+K + + + + + L+ V+ R+ E
Sbjct: 465 RIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIME 503
Score = 31.5 bits (68), Expect = 3.5
Identities = 30/168 (17%), Positives = 86/168 (51%), Gaps = 5/168 (2%)
Query: 12 KLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDL 71
++E++ A+ + D +Q + + +++ V ++ ++ L K K+E +
Sbjct: 387 EIEQELALAR-DGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRV 445
Query: 72 EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ-QSADENNRMCKVL 130
EE+ E + + +++++E+ L + ++ Q++L + + + E +R+ ++
Sbjct: 446 EEESITKGDLETQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELE 505
Query: 131 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
++ A + +E + +L +L E+ A D D S + ++++ ++++LEV
Sbjct: 506 KDLALRVQE-VAELRRRL-ESNKPAGDVD-MSLSLLQEISSLQEKLEV 550
>S67238-1|AAB28950.1| 296|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 296
Score = 64.1 bits (149), Expect = 5e-10
Identities = 59/290 (20%), Positives = 122/290 (42%), Gaps = 11/290 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQVEEDLILNK 61
AIK+ + KD + D + +RD K NE+ + L+ L Q++EDL +
Sbjct: 1 AIKQLRKLQAQMKDFQRELEDA--RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE 58
Query: 62 NKLEQANKDLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
+QA+ + EE ++L A + E L ++ Q+EE+LE+ + ++
Sbjct: 59 RARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 118
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK-SDEVSRKLAFVE 173
+A Q A++ + AQ++E QL Q KE R + +G + +A +E
Sbjct: 119 KATQQAEQLSNELATERTTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 178
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXX 233
++ E++V+ + + LK LK + + E + E++
Sbjct: 179 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAGVK 238
Query: 234 XXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAG 283
+ +++ +L+ EL + +++ E+++ ++L G
Sbjct: 239 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRG 288
>M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker
protein-170 alpha-2 protein.
Length = 1392
Score = 64.1 bits (149), Expect = 5e-10
Identities = 47/213 (22%), Positives = 108/213 (50%), Gaps = 15/213 (7%)
Query: 11 MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKD 70
+K ++ +D D + + + +K+ +++ +K++ +E + +K ++
Sbjct: 720 LKATEEKLLD-LDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRE 778
Query: 71 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
L+ +E +LT + ++ +V Q++E LEK + ++K EA + A R +
Sbjct: 779 LQGRELKLTNLQENLS----EVSQVKETLEKELQ---ILKEKFAEASEEAVSVQRSMQET 831
Query: 131 ENRAQQDEERMDQLTNQLKEARLLAEDADGK---SDEVSRKLAFVEDELE--VAEDRVKS 185
N+ Q EE+ + L++ L++ R D + K DE +L +++LE +AE S
Sbjct: 832 VNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMS 891
Query: 186 GD--AKISELEEELKVVGNSLKSLEVSEEKANQ 216
GD ++++++ +EL++ ++ L++ KAN+
Sbjct: 892 GDNSSQLTKMNDELRLKERDVEELQLKLTKANE 924
Score = 60.5 bits (140), Expect = 7e-09
Identities = 44/228 (19%), Positives = 103/228 (45%), Gaps = 8/228 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A +K+++ +++EK+ KA + ++ + L+ + E + E+ + +E++L +
Sbjct: 751 LEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQIL 810
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K K +A+++ ++ + T ++ + + DLEK E + K E +
Sbjct: 811 KEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDERE 870
Query: 121 DENNRMCKVLENR----AQQDEERMDQLTNQLKEARLLAEDADG---KSDEVSRKLAFVE 173
++ + + LEN + + QLT E RL D + K + + +F++
Sbjct: 871 EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQ 930
Query: 174 DELEVAEDRVKSGDAKISEL-EEELKVVGNSLKSLEVSEEKANQRVEE 220
+E + + + ++ EEE K + L LE E ++ + +E
Sbjct: 931 KSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQE 978
Score = 56.0 bits (129), Expect = 1e-07
Identities = 46/223 (20%), Positives = 97/223 (43%), Gaps = 14/223 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQAR----DANLRAEKVNEEVRELQK---KLAQV 53
+DA++K K E + + E+Q + + N + K + RELQ KL +
Sbjct: 730 LDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNL 789
Query: 54 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
+E+L E K+L+ +++ E ++ R +Q+ L + EE+ L
Sbjct: 790 QENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDL 849
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
+ +++ + + + R +Q + ++L N + E ++ D S +L +
Sbjct: 850 EKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDN-------SSQLTKMN 902
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
DEL + E V+ K+++ E + S++ + V E++ Q
Sbjct: 903 DELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQ 945
Score = 54.0 bits (124), Expect = 6e-07
Identities = 51/274 (18%), Positives = 113/274 (41%), Gaps = 14/274 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M+A++ K+ + EK+N+++ + +A D +L ++ + + +LQ+ +V+E +L
Sbjct: 646 MEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHL--VEMEDTLNKLQEAEIKVKELEVL- 702
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ K + K ++ QL ATE ++ ++ D + G ++ K L Q A
Sbjct: 703 QAKCNEQTKVIDNFTSQLKATEEKL---------LDLDALRKASSEGKSEMKKLRQQLEA 753
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
E + K LE + + +T +L+ L + EVS+ +E EL++ +
Sbjct: 754 AE--KQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILK 811
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
++ + ++ ++ N L E + +E+
Sbjct: 812 EKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREE 871
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
K +KL+ ++ + G N + + DE+
Sbjct: 872 QLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDEL 905
Score = 47.6 bits (108), Expect = 5e-05
Identities = 45/214 (21%), Positives = 88/214 (41%), Gaps = 7/214 (3%)
Query: 12 KLEKDNA--MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
KLE D A M + Q N +V ELQ KL + E+ + +E
Sbjct: 879 KLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTV 938
Query: 70 DLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
E+ +++ E E L RK+ +E+ +E S + + + A +++ + +
Sbjct: 939 KAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERA--TSETKTKHEE 996
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADG--KSDEVSRKLAFVEDELEVAEDRVKSG 186
+L+N + + D+L +E L ++ + K E ++ ED +++ E K
Sbjct: 997 ILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAKAAQTAEDAMQIMEQMTKEK 1056
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
++ LE+ + L+ +E + VEE
Sbjct: 1057 TETLASLEDTKQTNAKLQNELDTLKENNLKNVEE 1090
Score = 44.8 bits (101), Expect = 3e-04
Identities = 44/249 (17%), Positives = 105/249 (42%), Gaps = 8/249 (3%)
Query: 42 EVRELQKKLAQVEEDLILNKNKLE-QANKDLEEKEKQLTATEAEVAALNRK----VQQIE 96
E EL+ ++ ++ D L+ Q + + K++ A A++ + ++ ++ I
Sbjct: 609 EFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIR 668
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK--EARLL 154
L+K+E++ + L Q A+ + +VL+ + + + +D T+QLK E +LL
Sbjct: 669 SKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLL 728
Query: 155 AEDADGK-SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
DA K S E ++ + +LE AE ++K + + + + + L+ E+
Sbjct: 729 DLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTN 788
Query: 214 ANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADE 273
+ + E + +Q+ + ++L ++++ L+ +
Sbjct: 789 LQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSD 848
Query: 274 MDSTFAELA 282
++ LA
Sbjct: 849 LEKLRENLA 857
Score = 44.4 bits (100), Expect = 5e-04
Identities = 42/224 (18%), Positives = 105/224 (46%), Gaps = 16/224 (7%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAE--------KVNEEVRELQKKLAQVEED 56
++ ++ ++L+ A + A ++ D ++AE K EE +EL++KL+ +E+
Sbjct: 909 ERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKK 968
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAA-LNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ + N+ ++ E + E+ L + + E+ L+ + E + Q+L E
Sbjct: 969 METSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEE 1028
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL-AFVED 174
++ A++ K + A+ + M+Q+T + E ED + ++ +L E+
Sbjct: 1029 LRKQAEK----AKAAQT-AEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKEN 1083
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
L+ E+ KS + E ++++ +++L+ + + +Q++
Sbjct: 1084 NLKNVEELNKSKELLTVE-NQKMEEFRKEIETLKQAAAQKSQQL 1126
Score = 41.9 bits (94), Expect = 0.002
Identities = 42/211 (19%), Positives = 94/211 (44%), Gaps = 7/211 (3%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
M+ M EK + + +Q + + E + ++L + +E L + K+E+
Sbjct: 1049 MEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEF 1108
Query: 68 NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMC 127
K++E ++ +++AL + ++ E+L +S + T+ QKL E + +
Sbjct: 1109 RKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEV-TSHQKLEEERSVLNNQLLEM 1167
Query: 128 KVLENRAQQD-EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
K E++ +D +E L + L + D + +++ ++ + E A KS
Sbjct: 1168 KKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASA----KSL 1223
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQR 217
+ + LE + + +K+LE+ + K N+R
Sbjct: 1224 HSVVQTLESDKVKLELKVKNLEL-QLKENKR 1253
Score = 41.1 bits (92), Expect = 0.004
Identities = 36/178 (20%), Positives = 82/178 (46%), Gaps = 8/178 (4%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q A DA E++ +E E L ++ +N+L+ ++ + ++L ++ +
Sbjct: 1040 QTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLT 1099
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS----ADENNRMCKVLENRAQQDEERMD 142
N+K+++ +++E ++ + Q+L Q+ A+E R + + + +EER
Sbjct: 1100 VENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEER-S 1158
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 200
L NQL E + +DE + A ++ + + + DA++ +L E+ V+
Sbjct: 1159 VLNNQLLEMKKRESKFIKDADE---EKASLQKSISITSALLTEKDAELEKLRNEVTVL 1213
Score = 37.5 bits (83), Expect = 0.053
Identities = 41/136 (30%), Positives = 65/136 (47%), Gaps = 21/136 (15%)
Query: 76 KQLTATEAEVAALNRKVQQIEE-----DLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
++++ T A AL K Q IE+ DLE++E T+ +E + + + VL
Sbjct: 345 RKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVL 404
Query: 131 ENRAQQDE-----ERMD----QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E A+ D+ E D +L NQL+E + ED + +E S + +LEVA
Sbjct: 405 ELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEES----ITKGDLEVATV 460
Query: 182 RVKSGDAKISELEEEL 197
KS +I ELE++L
Sbjct: 461 SEKS---RIMELEKDL 473
Score = 34.3 bits (75), Expect = 0.49
Identities = 40/212 (18%), Positives = 93/212 (43%), Gaps = 7/212 (3%)
Query: 12 KLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDL 71
++E++ A+ + D +Q + + +++ V ++ ++ L K K+E +
Sbjct: 387 EIEQELALAR-DGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRV 445
Query: 72 EEKEKQLTATEAEVAALNRK--VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV 129
EE+ +T + EVA ++ K + ++E+DL + +++ LE+ + A + + +
Sbjct: 446 EEES--ITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRR-LESNKPAGDVDMSLSL 502
Query: 130 LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAK 189
L+ + E+ T+ +E L E + + +++ + E +S +K
Sbjct: 503 LQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSK 562
Query: 190 ISELEEELKVVGNSLKS-LEVSEEKANQRVEE 220
+ +E V KS LE + Q +EE
Sbjct: 563 LEHANKENSDVIALWKSKLETAIASHQQAMEE 594
>BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 64.1 bits (149), Expect = 5e-10
Identities = 52/281 (18%), Positives = 117/281 (41%), Gaps = 8/281 (2%)
Query: 11 MKLEKDNAMDKA-DTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
MK K ++M++ E++ + EE E K++ KNK+EQ +
Sbjct: 386 MKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKE 445
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV 129
+L KE Q + + A L ++ Q++++L + + Q KL ++ + +V
Sbjct: 446 ELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEV 505
Query: 130 LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED-------ELEVAEDR 182
L+ E+R L ++ RL E+ + ++ ++++ + + E+ +D
Sbjct: 506 LKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDM 565
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXX 242
+ + K++ L+++++ + L+ E +RV+
Sbjct: 566 LDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEK 625
Query: 243 XKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAG 283
+T+++L+++ DR E E D YK ++ + L G
Sbjct: 626 ERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQG 666
Score = 61.3 bits (142), Expect = 4e-09
Identities = 47/224 (20%), Positives = 101/224 (45%), Gaps = 5/224 (2%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++K+ ++ + +N ++ E+Q R + + + L +EE L
Sbjct: 566 LDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEK 625
Query: 61 KNKL----EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+ + EQ ++D EK++++ + ++ L KV ++ DL + E ++
Sbjct: 626 ERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSL 685
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
S + + K LE +Q +E ++ +QLK+A A +A S E+S ++ +E E+
Sbjct: 686 ASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARA-SPEMSDRIQHLEREI 744
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+D A++ L E LK V N + + ++V++
Sbjct: 745 TRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKD 788
Score = 48.8 bits (111), Expect = 2e-05
Identities = 51/210 (24%), Positives = 97/210 (46%), Gaps = 15/210 (7%)
Query: 13 LEKDNAMDKADTCEQQARDANLRA--EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKD 70
LE++ K ++ + QA L ++V E + KK+A++E + ++NK K
Sbjct: 740 LEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQ-VKDQNKKVANLKH 798
Query: 71 LEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
E+ EK+ +A E A LN QQ+++ L K ++R ++ L E+ Q E
Sbjct: 799 KEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREM 858
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
+ E+ E+++++L +++ + E K + LA E E + R +
Sbjct: 859 VLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLA--EKETHLTNLRAE- 915
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKAN 215
+ LEE L++ +L + +SE+ AN
Sbjct: 916 ---RRKHLEEVLEMKQEALLAA-ISEKDAN 941
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/241 (16%), Positives = 104/241 (43%), Gaps = 14/241 (5%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
E + ++ +++ L +EE++ + K+ + ++ EE+ KQ+ + + KV+Q++
Sbjct: 385 EMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLK 444
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
E+L E + ++K Q + + + + +++ LTNQ +++ E
Sbjct: 445 EELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIE 504
Query: 157 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
++ A ++ E++ R++ + +++ ++++ +++EEK Q
Sbjct: 505 VLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQ---------DMAEEKGTQ 555
Query: 217 RVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
E K ++ LQ+++ E ++ K+R KSL + +
Sbjct: 556 AGE-----IHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTN 610
Query: 277 T 277
T
Sbjct: 611 T 611
Score = 45.6 bits (103), Expect = 2e-04
Identities = 44/227 (19%), Positives = 91/227 (40%), Gaps = 11/227 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K+++ E K +T Q D+ E + E + +++ A ++ ++ + +
Sbjct: 471 VKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLR 530
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
LE+ L +K KQ+ E ++ +++ L+ E + Q+K+ Q+ +
Sbjct: 531 LEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDK 590
Query: 124 NRMCKVLENRA---QQDEERMDQLTNQLKEA--------RLLAEDADGKSDEVSRKLAFV 172
+ L+ R Q D D L+EA L E D E ++
Sbjct: 591 EKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNY 650
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ +L+ +++V +SE E L + SL S K + R++
Sbjct: 651 KKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLK 697
Score = 41.9 bits (94), Expect = 0.002
Identities = 46/261 (17%), Positives = 112/261 (42%), Gaps = 13/261 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D KK ++ +K EK + + + D E++A +L+ + L+K ++ L
Sbjct: 647 IDNYKKDLKDLK-EKVSLL-QGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALE 704
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAA-LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
+ K E + + K+ A EA + ++ ++Q +E ++ + ++ S AQ ++
Sbjct: 705 QKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEV------ 758
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
D + K +EN ++++ +L Q+K+ + K +K A + +E
Sbjct: 759 -DRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRR 817
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
ED + +L++ L+ + ++ LE + ++ Q E
Sbjct: 818 EDNLNDSS---QQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQV 874
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
++K+++E++ ++ +L
Sbjct: 875 EELLMAMEKVKQELESMKAKL 895
Score = 39.9 bits (89), Expect = 0.010
Identities = 46/206 (22%), Positives = 87/206 (42%), Gaps = 9/206 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D + + ++ ++ EK++ K E+Q +D N + + + + +KK AQ+ E+
Sbjct: 758 VDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRR 817
Query: 61 KNKLEQANKDLEEK-EKQLTATEAEVAALNRKVQ-QIEEDLEKSEERSGTAQ-----QKL 113
++ L +++ L++ K+ E AL VQ E ++ ++E S ++L
Sbjct: 818 EDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEEL 877
Query: 114 LEAQQSADENNRMCKVLENRAQQD-EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 172
L A + + K + QQ E+ LTN E R E+ E + A
Sbjct: 878 LMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQE-ALLAAIS 936
Query: 173 EDELEVAEDRVKSGDAKISELEEELK 198
E + +A + S K E LK
Sbjct: 937 EKDANIALLELSSSKKKTQEEVAALK 962
Score = 38.7 bits (86), Expect = 0.023
Identities = 31/170 (18%), Positives = 77/170 (45%), Gaps = 3/170 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q +A R + +N+ ++LQ L + ++ + + L ++ + E+E L E+
Sbjct: 809 QMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESART 868
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
++V+++ +EK ++ + + KL QQS E L ++ E + ++
Sbjct: 869 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQ 928
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 196
+ A + +DA+ E+S ++E+ + + D + +L+++
Sbjct: 929 EALLAAISEKDANIALLELSSSKKKTQEEVAALK---REKDRLVQQLKQQ 975
Score = 37.1 bits (82), Expect = 0.070
Identities = 44/185 (23%), Positives = 86/185 (46%), Gaps = 23/185 (12%)
Query: 36 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI 95
AE E + L + + ++L L + K LEE E ++ E + LN + + I
Sbjct: 260 AELTEENFQRLHAEHERQAKELFLLR-------KTLEEMELRI---ETQKQTLNARDESI 309
Query: 96 EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL-KEARLL 154
++ LE Q K L A+ + +++ R ++ E A+ ++ L Q KE +L
Sbjct: 310 KKLLE-------MLQSKGLSAKATEEDHERTRRLAE--AEMHVHHLESLLEQKEKENSML 360
Query: 155 AEDADGKSDEV--SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV-GNSLKSLEVSE 211
E+ + + S K ++ +E+ + ++ S + + +LEEE++++ N S E E
Sbjct: 361 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE 420
Query: 212 EKANQ 216
E+ Q
Sbjct: 421 EEMKQ 425
>BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 64.1 bits (149), Expect = 5e-10
Identities = 52/281 (18%), Positives = 117/281 (41%), Gaps = 8/281 (2%)
Query: 11 MKLEKDNAMDKA-DTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
MK K ++M++ E++ + EE E K++ KNK+EQ +
Sbjct: 386 MKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKE 445
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV 129
+L KE Q + + A L ++ Q++++L + + Q KL ++ + +V
Sbjct: 446 ELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEV 505
Query: 130 LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED-------ELEVAEDR 182
L+ E+R L ++ RL E+ + ++ ++++ + + E+ +D
Sbjct: 506 LKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDM 565
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXX 242
+ + K++ L+++++ + L+ E +RV+
Sbjct: 566 LDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEK 625
Query: 243 XKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAG 283
+T+++L+++ DR E E D YK ++ + L G
Sbjct: 626 ERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQG 666
Score = 61.3 bits (142), Expect = 4e-09
Identities = 47/224 (20%), Positives = 101/224 (45%), Gaps = 5/224 (2%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++K+ ++ + +N ++ E+Q R + + + L +EE L
Sbjct: 566 LDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEK 625
Query: 61 KNKL----EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+ + EQ ++D EK++++ + ++ L KV ++ DL + E ++
Sbjct: 626 ERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSL 685
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
S + + K LE +Q +E ++ +QLK+A A +A S E+S ++ +E E+
Sbjct: 686 ASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARA-SPEMSDRIQHLEREI 744
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+D A++ L E LK V N + + ++V++
Sbjct: 745 TRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKD 788
Score = 48.8 bits (111), Expect = 2e-05
Identities = 51/210 (24%), Positives = 97/210 (46%), Gaps = 15/210 (7%)
Query: 13 LEKDNAMDKADTCEQQARDANLRA--EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKD 70
LE++ K ++ + QA L ++V E + KK+A++E + ++NK K
Sbjct: 740 LEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQ-VKDQNKKVANLKH 798
Query: 71 LEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
E+ EK+ +A E A LN QQ+++ L K ++R ++ L E+ Q E
Sbjct: 799 KEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREM 858
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
+ E+ E+++++L +++ + E K + LA E E + R +
Sbjct: 859 VLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLA--EKETHLTNLRAE- 915
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKAN 215
+ LEE L++ +L + +SE+ AN
Sbjct: 916 ---RRKHLEEVLEMKQEALLAA-ISEKDAN 941
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/241 (16%), Positives = 104/241 (43%), Gaps = 14/241 (5%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
E + ++ +++ L +EE++ + K+ + ++ EE+ KQ+ + + KV+Q++
Sbjct: 385 EMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLK 444
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
E+L E + ++K Q + + + + +++ LTNQ +++ E
Sbjct: 445 EELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIE 504
Query: 157 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
++ A ++ E++ R++ + +++ ++++ +++EEK Q
Sbjct: 505 VLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQ---------DMAEEKGTQ 555
Query: 217 RVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
E K ++ LQ+++ E ++ K+R KSL + +
Sbjct: 556 AGE-----IHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTN 610
Query: 277 T 277
T
Sbjct: 611 T 611
Score = 45.6 bits (103), Expect = 2e-04
Identities = 44/227 (19%), Positives = 91/227 (40%), Gaps = 11/227 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K+++ E K +T Q D+ E + E + +++ A ++ ++ + +
Sbjct: 471 VKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLR 530
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
LE+ L +K KQ+ E ++ +++ L+ E + Q+K+ Q+ +
Sbjct: 531 LEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDK 590
Query: 124 NRMCKVLENRA---QQDEERMDQLTNQLKEA--------RLLAEDADGKSDEVSRKLAFV 172
+ L+ R Q D D L+EA L E D E ++
Sbjct: 591 EKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNY 650
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ +L+ +++V +SE E L + SL S K + R++
Sbjct: 651 KKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLK 697
Score = 41.9 bits (94), Expect = 0.002
Identities = 46/261 (17%), Positives = 112/261 (42%), Gaps = 13/261 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D KK ++ +K EK + + + D E++A +L+ + L+K ++ L
Sbjct: 647 IDNYKKDLKDLK-EKVSLL-QGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALE 704
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAA-LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
+ K E + + K+ A EA + ++ ++Q +E ++ + ++ S AQ ++
Sbjct: 705 QKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEV------ 758
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
D + K +EN ++++ +L Q+K+ + K +K A + +E
Sbjct: 759 -DRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRR 817
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
ED + +L++ L+ + ++ LE + ++ Q E
Sbjct: 818 EDNLNDSS---QQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQV 874
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
++K+++E++ ++ +L
Sbjct: 875 EELLMAMEKVKQELESMKAKL 895
Score = 39.9 bits (89), Expect = 0.010
Identities = 46/206 (22%), Positives = 87/206 (42%), Gaps = 9/206 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D + + ++ ++ EK++ K E+Q +D N + + + + +KK AQ+ E+
Sbjct: 758 VDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRR 817
Query: 61 KNKLEQANKDLEEK-EKQLTATEAEVAALNRKVQ-QIEEDLEKSEERSGTAQ-----QKL 113
++ L +++ L++ K+ E AL VQ E ++ ++E S ++L
Sbjct: 818 EDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEEL 877
Query: 114 LEAQQSADENNRMCKVLENRAQQD-EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 172
L A + + K + QQ E+ LTN E R E+ E + A
Sbjct: 878 LMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQE-ALLAAIS 936
Query: 173 EDELEVAEDRVKSGDAKISELEEELK 198
E + +A + S K E LK
Sbjct: 937 EKDANIALLELSSSKKKTQEEVAALK 962
Score = 38.7 bits (86), Expect = 0.023
Identities = 31/170 (18%), Positives = 77/170 (45%), Gaps = 3/170 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q +A R + +N+ ++LQ L + ++ + + L ++ + E+E L E+
Sbjct: 809 QMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESART 868
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
++V+++ +EK ++ + + KL QQS E L ++ E + ++
Sbjct: 869 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQ 928
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 196
+ A + +DA+ E+S ++E+ + + D + +L+++
Sbjct: 929 EALLAAISEKDANIALLELSSSKKKTQEEVAALK---REKDRLVQQLKQQ 975
Score = 37.1 bits (82), Expect = 0.070
Identities = 44/185 (23%), Positives = 86/185 (46%), Gaps = 23/185 (12%)
Query: 36 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI 95
AE E + L + + ++L L + K LEE E ++ E + LN + + I
Sbjct: 260 AELTEENFQRLHAEHERQAKELFLLR-------KTLEEMELRI---ETQKQTLNARDESI 309
Query: 96 EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL-KEARLL 154
++ LE Q K L A+ + +++ R ++ E A+ ++ L Q KE +L
Sbjct: 310 KKLLE-------MLQSKGLSAKATEEDHERTRRLAE--AEMHVHHLESLLEQKEKENSML 360
Query: 155 AEDADGKSDEV--SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV-GNSLKSLEVSE 211
E+ + + S K ++ +E+ + ++ S + + +LEEE++++ N S E E
Sbjct: 361 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE 420
Query: 212 EKANQ 216
E+ Q
Sbjct: 421 EEMKQ 425
>BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 64.1 bits (149), Expect = 5e-10
Identities = 47/213 (22%), Positives = 108/213 (50%), Gaps = 15/213 (7%)
Query: 11 MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKD 70
+K ++ +D D + + + +K+ +++ +K++ +E + +K ++
Sbjct: 766 LKATEEKLLD-LDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRE 824
Query: 71 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
L+ +E +LT + ++ +V Q++E LEK + ++K EA + A R +
Sbjct: 825 LQGRELKLTNLQENLS----EVSQVKETLEKELQ---ILKEKFAEASEEAVSVQRSMQET 877
Query: 131 ENRAQQDEERMDQLTNQLKEARLLAEDADGK---SDEVSRKLAFVEDELE--VAEDRVKS 185
N+ Q EE+ + L++ L++ R D + K DE +L +++LE +AE S
Sbjct: 878 VNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMS 937
Query: 186 GD--AKISELEEELKVVGNSLKSLEVSEEKANQ 216
GD ++++++ +EL++ ++ L++ KAN+
Sbjct: 938 GDNSSQLTKMNDELRLKERDVEELQLKLTKANE 970
Score = 60.5 bits (140), Expect = 7e-09
Identities = 44/228 (19%), Positives = 103/228 (45%), Gaps = 8/228 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A +K+++ +++EK+ KA + ++ + L+ + E + E+ + +E++L +
Sbjct: 797 LEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQIL 856
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K K +A+++ ++ + T ++ + + DLEK E + K E +
Sbjct: 857 KEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDERE 916
Query: 121 DENNRMCKVLENR----AQQDEERMDQLTNQLKEARLLAEDADG---KSDEVSRKLAFVE 173
++ + + LEN + + QLT E RL D + K + + +F++
Sbjct: 917 EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQ 976
Query: 174 DELEVAEDRVKSGDAKISEL-EEELKVVGNSLKSLEVSEEKANQRVEE 220
+E + + + ++ EEE K + L LE E ++ + +E
Sbjct: 977 KSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQE 1024
Score = 56.0 bits (129), Expect = 1e-07
Identities = 46/223 (20%), Positives = 97/223 (43%), Gaps = 14/223 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQAR----DANLRAEKVNEEVRELQK---KLAQV 53
+DA++K K E + + E+Q + + N + K + RELQ KL +
Sbjct: 776 LDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNL 835
Query: 54 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
+E+L E K+L+ +++ E ++ R +Q+ L + EE+ L
Sbjct: 836 QENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDL 895
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
+ +++ + + + R +Q + ++L N + E ++ D S +L +
Sbjct: 896 EKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDN-------SSQLTKMN 948
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
DEL + E V+ K+++ E + S++ + V E++ Q
Sbjct: 949 DELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQ 991
Score = 54.0 bits (124), Expect = 6e-07
Identities = 51/274 (18%), Positives = 113/274 (41%), Gaps = 14/274 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M+A++ K+ + EK+N+++ + +A D +L ++ + + +LQ+ +V+E +L
Sbjct: 692 MEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHL--VEMEDTLNKLQEAEIKVKELEVL- 748
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ K + K ++ QL ATE ++ ++ D + G ++ K L Q A
Sbjct: 749 QAKCNEQTKVIDNFTSQLKATEEKL---------LDLDALRKASSEGKSEMKKLRQQLEA 799
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
E + K LE + + +T +L+ L + EVS+ +E EL++ +
Sbjct: 800 AE--KQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILK 857
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
++ + ++ ++ N L E + +E+
Sbjct: 858 EKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREE 917
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
K +KL+ ++ + G N + + DE+
Sbjct: 918 QLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDEL 951
Score = 46.4 bits (105), Expect = 1e-04
Identities = 44/214 (20%), Positives = 88/214 (41%), Gaps = 7/214 (3%)
Query: 12 KLEKDNA--MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
KLE D A M + Q N +V ELQ KL + E+ + +E
Sbjct: 925 KLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTV 984
Query: 70 DLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
E+ +++ E E L RK+ +E+ +E S + + + A +++ + +
Sbjct: 985 KAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERA--TSETKTKHEE 1042
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADG--KSDEVSRKLAFVEDELEVAEDRVKSG 186
+L+N + + D+L +E L ++ + K + ++ ED +++ E K
Sbjct: 1043 ILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEK 1102
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
++ LE+ + L+ +E + VEE
Sbjct: 1103 TETLASLEDTKQTNAKLQNELDTLKENNLKNVEE 1136
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/224 (19%), Positives = 105/224 (46%), Gaps = 16/224 (7%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAE--------KVNEEVRELQKKLAQVEED 56
++ ++ ++L+ A + A ++ D ++AE K EE +EL++KL+ +E+
Sbjct: 955 ERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKK 1014
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAA-LNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ + N+ ++ E + E+ L + + E+ L+ + E + Q+L E
Sbjct: 1015 METSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEE 1074
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL-AFVED 174
++ AD+ K + A+ + M+Q+T + E ED + ++ +L E+
Sbjct: 1075 LRKQADK----AKAAQT-AEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKEN 1129
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
L+ E+ KS + E ++++ +++L+ + + +Q++
Sbjct: 1130 NLKNVEELNKSKELLTVE-NQKMEEFRKEIETLKQAAAQKSQQL 1172
Score = 44.8 bits (101), Expect = 3e-04
Identities = 44/249 (17%), Positives = 105/249 (42%), Gaps = 8/249 (3%)
Query: 42 EVRELQKKLAQVEEDLILNKNKLE-QANKDLEEKEKQLTATEAEVAALNRK----VQQIE 96
E EL+ ++ ++ D L+ Q + + K++ A A++ + ++ ++ I
Sbjct: 655 EFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIR 714
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK--EARLL 154
L+K+E++ + L Q A+ + +VL+ + + + +D T+QLK E +LL
Sbjct: 715 SKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLL 774
Query: 155 AEDADGK-SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
DA K S E ++ + +LE AE ++K + + + + + L+ E+
Sbjct: 775 DLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTN 834
Query: 214 ANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADE 273
+ + E + +Q+ + ++L ++++ L+ +
Sbjct: 835 LQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSD 894
Query: 274 MDSTFAELA 282
++ LA
Sbjct: 895 LEKLRENLA 903
Score = 42.3 bits (95), Expect = 0.002
Identities = 40/140 (28%), Positives = 67/140 (47%), Gaps = 18/140 (12%)
Query: 76 KQLTATEAEVAALNRKVQQIEE-----DLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
++++ T A AL K Q IE+ DLE++E T+ +E + + + VL
Sbjct: 345 RKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVL 404
Query: 131 ENRAQQDE-----ERMD----QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E A+ D+ E D +L NQL+E + ED + +E S +E + +++ED
Sbjct: 405 ELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQISED 464
Query: 182 ----RVKSGDAKISELEEEL 197
+ K A+I ELE+ L
Sbjct: 465 PENTQTKLEHARIKELEQSL 484
Score = 42.3 bits (95), Expect = 0.002
Identities = 39/185 (21%), Positives = 85/185 (45%), Gaps = 9/185 (4%)
Query: 20 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 79
DKA Q A DA E++ +E E L ++ +N+L+ ++ + ++L
Sbjct: 1080 DKAKAA-QTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELN 1138
Query: 80 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS----ADENNRMCKVLENRAQ 135
++ + N+K+++ +++E ++ + Q+L Q+ A+E R + + +
Sbjct: 1139 KSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQK 1198
Query: 136 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 195
+EER L NQL E + +DE + A ++ + + + DA++ +L
Sbjct: 1199 LEEER-SVLNNQLLEMKKRESKFIKDADE---EKASLQKSISITSALLTEKDAELEKLRN 1254
Query: 196 ELKVV 200
E+ V+
Sbjct: 1255 EVTVL 1259
Score = 41.9 bits (94), Expect = 0.002
Identities = 42/211 (19%), Positives = 94/211 (44%), Gaps = 7/211 (3%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
M+ M EK + + +Q + + E + ++L + +E L + K+E+
Sbjct: 1095 MEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEF 1154
Query: 68 NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMC 127
K++E ++ +++AL + ++ E+L +S + T+ QKL E + +
Sbjct: 1155 RKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEV-TSHQKLEEERSVLNNQLLEM 1213
Query: 128 KVLENRAQQD-EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
K E++ +D +E L + L + D + +++ ++ + E A KS
Sbjct: 1214 KKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASA----KSL 1269
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQR 217
+ + LE + + +K+LE+ + K N+R
Sbjct: 1270 HSVVQTLESDKVKLELKVKNLEL-QLKENKR 1299
Score = 39.5 bits (88), Expect = 0.013
Identities = 47/196 (23%), Positives = 89/196 (45%), Gaps = 20/196 (10%)
Query: 35 RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 94
R E +E++ L ++ ++ K+KLE ANK E + ++++ QQ
Sbjct: 580 REETHQKEIKALYTATEKLSKENESLKSKLEHANK---ENSDVIALWKSKLETAIASHQQ 636
Query: 95 IEEDLEKSEERS-GTAQQKLLEAQQSADENNRMCK-VLEN-RAQQDEERMDQLTN-QLKE 150
E+L+ S + GT + E + ++ + +EN + QQD ER +
Sbjct: 637 AMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALR 696
Query: 151 ARLL--AEDADGKSDEVSRKLAFVED----ELEVAEDRVKSGDAKISELE-------EEL 197
A+L+ ++ + + + KL ED E+E ++++ + K+ ELE E+
Sbjct: 697 AKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQT 756
Query: 198 KVVGNSLKSLEVSEEK 213
KV+ N L+ +EEK
Sbjct: 757 KVIDNFTSQLKATEEK 772
Score = 32.3 bits (70), Expect = 2.0
Identities = 31/148 (20%), Positives = 71/148 (47%), Gaps = 12/148 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
IK+ Q++ EK KAD +++ D + + EL+K LA +++ + +
Sbjct: 477 IKELEQSLLFEKT----KADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRR 532
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
LE +NK + + L+ + E+++L K++ D +R T+ ++ A++ + +
Sbjct: 533 LE-SNKPAGDVDMSLSLLQ-EISSLQEKLEVTRTD----HQREITSLKEHFGARE--ETH 584
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEA 151
+ K L ++ + + L ++L+ A
Sbjct: 585 QKEIKALYTATEKLSKENESLKSKLEHA 612
>BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 64.1 bits (149), Expect = 5e-10
Identities = 47/213 (22%), Positives = 108/213 (50%), Gaps = 15/213 (7%)
Query: 11 MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKD 70
+K ++ +D D + + + +K+ +++ +K++ +E + +K ++
Sbjct: 766 LKATEEKLLD-LDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRE 824
Query: 71 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
L+ +E +LT + ++ +V Q++E LEK + ++K EA + A R +
Sbjct: 825 LQGRELKLTNLQENLS----EVSQVKETLEKELQ---ILKEKFAEASEEAVSVQRSMQET 877
Query: 131 ENRAQQDEERMDQLTNQLKEARLLAEDADGK---SDEVSRKLAFVEDELE--VAEDRVKS 185
N+ Q EE+ + L++ L++ R D + K DE +L +++LE +AE S
Sbjct: 878 VNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMS 937
Query: 186 GD--AKISELEEELKVVGNSLKSLEVSEEKANQ 216
GD ++++++ +EL++ ++ L++ KAN+
Sbjct: 938 GDNPSQLTKMNDELRLKERDVEELQLKLTKANE 970
Score = 60.1 bits (139), Expect = 9e-09
Identities = 44/228 (19%), Positives = 103/228 (45%), Gaps = 8/228 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A +K+++ +++EK+ KA + ++ + L+ + E + E+ + +E++L +
Sbjct: 797 LEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQIL 856
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K K +A+++ ++ + T ++ + + DLEK E + K E +
Sbjct: 857 KEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDERE 916
Query: 121 DENNRMCKVLENR----AQQDEERMDQLTNQLKEARLLAEDADG---KSDEVSRKLAFVE 173
++ + + LEN + + QLT E RL D + K + + +F++
Sbjct: 917 EQLIKAKEKLENDIAEIMKMSGDNPSQLTKMNDELRLKERDVEELQLKLTKANENASFLQ 976
Query: 174 DELEVAEDRVKSGDAKISEL-EEELKVVGNSLKSLEVSEEKANQRVEE 220
+E + + + ++ EEE K + L LE E ++ + +E
Sbjct: 977 KSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQE 1024
Score = 54.8 bits (126), Expect = 3e-07
Identities = 46/223 (20%), Positives = 97/223 (43%), Gaps = 14/223 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQAR----DANLRAEKVNEEVRELQK---KLAQV 53
+DA++K K E + + E+Q + + N + K + RELQ KL +
Sbjct: 776 LDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNL 835
Query: 54 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
+E+L E K+L+ +++ E ++ R +Q+ L + EE+ L
Sbjct: 836 QENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDL 895
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
+ +++ + + + R +Q + ++L N + A ++ D S +L +
Sbjct: 896 EKLRENLADMEAKFREKDEREEQLIKAKEKLENDI--AEIMKMSGDNPS-----QLTKMN 948
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
DEL + E V+ K+++ E + S++ + V E++ Q
Sbjct: 949 DELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQ 991
Score = 53.6 bits (123), Expect = 8e-07
Identities = 51/274 (18%), Positives = 113/274 (41%), Gaps = 14/274 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M+A++ K+ + EK+N+++ + +A D +L ++ + + +LQ+ +V+E +L
Sbjct: 692 MEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHL--VEMEDTLNKLQEAEIKVKELEVL- 748
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ K + K ++ QL ATE ++ ++ D + G ++ K L Q A
Sbjct: 749 QAKCNEQTKVIDNFTSQLKATEEKL---------LDLDALRKASSEGKSEMKKLRQQLEA 799
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
E + K LE + + +T +L+ L + EVS+ +E EL++ +
Sbjct: 800 AE--KQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILK 857
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
++ + ++ ++ N L E + +E+
Sbjct: 858 EKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREE 917
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
K +KL+ ++ + G N + + DE+
Sbjct: 918 QLIKAKEKLENDIAEIMKMSGDNPSQLTKMNDEL 951
Score = 47.2 bits (107), Expect = 7e-05
Identities = 45/214 (21%), Positives = 88/214 (41%), Gaps = 7/214 (3%)
Query: 12 KLEKDNA--MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
KLE D A M + Q N +V ELQ KL + E+ + +E
Sbjct: 925 KLENDIAEIMKMSGDNPSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTV 984
Query: 70 DLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
E+ +++ E E L RK+ +E+ +E S + + + A +++ + +
Sbjct: 985 KAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERA--TSETKTKHEE 1042
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADG--KSDEVSRKLAFVEDELEVAEDRVKSG 186
+L+N + + D+L +E L ++ + K E ++ ED +++ E K
Sbjct: 1043 ILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAKAAQTAEDAMQIMEQMTKEK 1102
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
++ LE+ + L+ +E + VEE
Sbjct: 1103 TETLASLEDTKQTNAKLQNELDTLKENNLKNVEE 1136
Score = 44.8 bits (101), Expect = 3e-04
Identities = 44/249 (17%), Positives = 105/249 (42%), Gaps = 8/249 (3%)
Query: 42 EVRELQKKLAQVEEDLILNKNKLE-QANKDLEEKEKQLTATEAEVAALNRK----VQQIE 96
E EL+ ++ ++ D L+ Q + + K++ A A++ + ++ ++ I
Sbjct: 655 EFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIR 714
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK--EARLL 154
L+K+E++ + L Q A+ + +VL+ + + + +D T+QLK E +LL
Sbjct: 715 SKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLL 774
Query: 155 AEDADGK-SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
DA K S E ++ + +LE AE ++K + + + + + L+ E+
Sbjct: 775 DLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTN 834
Query: 214 ANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADE 273
+ + E + +Q+ + ++L ++++ L+ +
Sbjct: 835 LQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSD 894
Query: 274 MDSTFAELA 282
++ LA
Sbjct: 895 LEKLRENLA 903
Score = 44.4 bits (100), Expect = 5e-04
Identities = 42/224 (18%), Positives = 105/224 (46%), Gaps = 16/224 (7%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAE--------KVNEEVRELQKKLAQVEED 56
++ ++ ++L+ A + A ++ D ++AE K EE +EL++KL+ +E+
Sbjct: 955 ERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKK 1014
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAA-LNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ + N+ ++ E + E+ L + + E+ L+ + E + Q+L E
Sbjct: 1015 METSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEE 1074
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL-AFVED 174
++ A++ K + A+ + M+Q+T + E ED + ++ +L E+
Sbjct: 1075 LRKQAEK----AKAAQT-AEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKEN 1129
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
L+ E+ KS + E ++++ +++L+ + + +Q++
Sbjct: 1130 NLKNVEELNKSKELLTVE-NQKMEEFRKEIETLKQAAAQKSQQL 1172
Score = 42.3 bits (95), Expect = 0.002
Identities = 40/140 (28%), Positives = 67/140 (47%), Gaps = 18/140 (12%)
Query: 76 KQLTATEAEVAALNRKVQQIEE-----DLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
++++ T A AL K Q IE+ DLE++E T+ +E + + + VL
Sbjct: 345 RKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVL 404
Query: 131 ENRAQQDE-----ERMD----QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E A+ D+ E D +L NQL+E + ED + +E S +E + +++ED
Sbjct: 405 ELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQISED 464
Query: 182 ----RVKSGDAKISELEEEL 197
+ K A+I ELE+ L
Sbjct: 465 PENTQTKLEHARIKELEQSL 484
Score = 41.9 bits (94), Expect = 0.002
Identities = 42/211 (19%), Positives = 94/211 (44%), Gaps = 7/211 (3%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
M+ M EK + + +Q + + E + ++L + +E L + K+E+
Sbjct: 1095 MEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEF 1154
Query: 68 NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMC 127
K++E ++ +++AL + ++ E+L +S + T+ QKL E + +
Sbjct: 1155 RKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEV-TSHQKLEEERSVLNNQLLEM 1213
Query: 128 KVLENRAQQD-EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
K E++ +D +E L + L + D + +++ ++ + E A KS
Sbjct: 1214 KKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASA----KSL 1269
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQR 217
+ + LE + + +K+LE+ + K N+R
Sbjct: 1270 HSVVQTLESDKVKLELKVKNLEL-QLKENKR 1299
Score = 41.1 bits (92), Expect = 0.004
Identities = 36/178 (20%), Positives = 82/178 (46%), Gaps = 8/178 (4%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q A DA E++ +E E L ++ +N+L+ ++ + ++L ++ +
Sbjct: 1086 QTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLT 1145
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS----ADENNRMCKVLENRAQQDEERMD 142
N+K+++ +++E ++ + Q+L Q+ A+E R + + + +EER
Sbjct: 1146 VENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEER-S 1204
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 200
L NQL E + +DE + A ++ + + + DA++ +L E+ V+
Sbjct: 1205 VLNNQLLEMKKRESKFIKDADE---EKASLQKSISITSALLTEKDAELEKLRNEVTVL 1259
Score = 39.5 bits (88), Expect = 0.013
Identities = 47/196 (23%), Positives = 89/196 (45%), Gaps = 20/196 (10%)
Query: 35 RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 94
R E +E++ L ++ ++ K+KLE ANK E + ++++ QQ
Sbjct: 580 REETHQKEIKALYTATEKLSKENESLKSKLEHANK---ENSDVIALWKSKLETAIASHQQ 636
Query: 95 IEEDLEKSEERS-GTAQQKLLEAQQSADENNRMCK-VLEN-RAQQDEERMDQLTN-QLKE 150
E+L+ S + GT + E + ++ + +EN + QQD ER +
Sbjct: 637 AMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALR 696
Query: 151 ARLL--AEDADGKSDEVSRKLAFVED----ELEVAEDRVKSGDAKISELE-------EEL 197
A+L+ ++ + + + KL ED E+E ++++ + K+ ELE E+
Sbjct: 697 AKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQT 756
Query: 198 KVVGNSLKSLEVSEEK 213
KV+ N L+ +EEK
Sbjct: 757 KVIDNFTSQLKATEEK 772
Score = 32.3 bits (70), Expect = 2.0
Identities = 31/148 (20%), Positives = 71/148 (47%), Gaps = 12/148 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
IK+ Q++ EK KAD +++ D + + EL+K LA +++ + +
Sbjct: 477 IKELEQSLLFEKT----KADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRR 532
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
LE +NK + + L+ + E+++L K++ D +R T+ ++ A++ + +
Sbjct: 533 LE-SNKPAGDVDMSLSLLQ-EISSLQEKLEVTRTD----HQREITSLKEHFGARE--ETH 584
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEA 151
+ K L ++ + + L ++L+ A
Sbjct: 585 QKEIKALYTATEKLSKENESLKSKLEHA 612
>AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain protein.
Length = 1938
Score = 64.1 bits (149), Expect = 5e-10
Identities = 50/209 (23%), Positives = 111/209 (53%), Gaps = 17/209 (8%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKK++A + E +N++ ++ E++A+ A A + EE+++ Q A +E +
Sbjct: 1731 KKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 1787
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
KN LEQ KDL+ + + A + + +++Q++E + + E Q++ EA + A
Sbjct: 1788 KN-LEQTVKDLQHRLDE--AEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGA 1844
Query: 121 DENNRMCKVLENRAQQD-------EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
+ R K + +A++D ++ +D+L ++K + AE+A+ +++ + V+
Sbjct: 1845 HKYERKVKEMTYQAEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQ 1904
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGN 202
ELE A +R ++++++L + + VG+
Sbjct: 1905 HELEEAAERADIAESQVNKLRAKSRDVGS 1933
Score = 60.9 bits (141), Expect = 5e-09
Identities = 50/216 (23%), Positives = 103/216 (47%), Gaps = 14/216 (6%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL---NKNKLEQANKD 70
+K N DK + ++ D L KV +E + K+ + E++ N +KL + K
Sbjct: 943 KKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKS 1002
Query: 71 LEEKEKQ----LTATEAEVAAL---NRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L+E +Q L E +V L N K++Q +DLE S E+ + L A++ + +
Sbjct: 1003 LQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGD 1062
Query: 124 NRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+M + LEN QQ EE++ + +L + + +D S + +K+ ++ +E
Sbjct: 1063 LKMSQESIMDLENEKQQIEEKLKKKEFELSQLQARIDDEQVHSLQFQKKIKELQARIEEL 1122
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
E+ +++ +++E++ + L+ + E+A+
Sbjct: 1123 EEEIEAEHTLRAKIEKQRSDLARELEEISERLEEAS 1158
Score = 59.7 bits (138), Expect = 1e-08
Identities = 51/274 (18%), Positives = 121/274 (44%), Gaps = 12/274 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKK---LAQVEEDLILN 60
++K+ +K+E D+ + + + V ++ E++ K Q+ DL +
Sbjct: 1221 LEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQ 1280
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K +L+ N +L + ++ + +++ + + Q E+L++ E A+ + A QS+
Sbjct: 1281 KARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSS 1340
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ C +L + ++++E +L L +A +E A K+ + + E ELE A+
Sbjct: 1341 RHD---CDLLREQYEEEQEAKAELQRALSKAN--SEVAQWKTKYETDAIQRTE-ELEEAK 1394
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
++ ++ E EE+ + + SLE ++++ VE+
Sbjct: 1395 KKLAQ---RLQEAEEKTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQR 1451
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
K + + ++++D + EL + +SL+ E+
Sbjct: 1452 NFDKVLAEWKQKLDESQAELEAAQKESRSLSTEL 1485
Score = 53.6 bits (123), Expect = 8e-07
Identities = 55/262 (20%), Positives = 109/262 (41%), Gaps = 20/262 (7%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA----NK 69
E +N MD + CE + L KV E L+++ ++ +L+ K LE +
Sbjct: 898 ETENLMDAEERCEGLIKSKILLEAKVKELTERLEEE-EEMNSELVAKKRNLEDKCSSLKR 956
Query: 70 DLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEK--SEERS--GTAQQKLLEAQQ 118
D+++ E LT ATE +V L+ ++ +EE++ K E++S QQ L + Q
Sbjct: 957 DIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQV 1016
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
D+ N + K+ QQ D L L++ + L D + ++ L ++ +
Sbjct: 1017 EEDKVNGLIKINAKLEQQ----TDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMD 1072
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXX 238
E+ + + K+ + E EL + + +V + ++++E
Sbjct: 1073 LENEKQQIEEKLKKKEFELSQLQARIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTL 1132
Query: 239 XXXXXKTVKKLQKEVDRLEDEL 260
K L +E++ + + L
Sbjct: 1133 RAKIEKQRSDLARELEEISERL 1154
Score = 49.6 bits (113), Expect = 1e-05
Identities = 47/284 (16%), Positives = 121/284 (42%), Gaps = 1/284 (0%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+A++ + A +++A+ E + ++ N ++ E Q+ L V+ L ++
Sbjct: 1599 EALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQRHLRTVQGQLKDSQ 1658
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
L+ A + E+ ++QL E L ++++++ LE++E ++Q+LL+A
Sbjct: 1659 LHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQ 1718
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
+ L N ++ E + Q +++ + + +A+ K+ + A + +EL+ +D
Sbjct: 1719 LLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQD 1778
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+ LE+ +K + + L E ++ + +++++
Sbjct: 1779 TSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGA 1838
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K K +++V + + ++ L D +D A++ Y
Sbjct: 1839 EALKGAHKYERKVKEMTYQAEEDRKNILRLQDLVDKLQAKVKSY 1882
Score = 48.8 bits (111), Expect = 2e-05
Identities = 53/227 (23%), Positives = 102/227 (44%), Gaps = 17/227 (7%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
IK +++ + EK+ A K D ++ ++ R+E +E+ E L Q + DL L +
Sbjct: 840 IKPLLKSAEAEKEMATMKEDF--ERTKEELARSEARRKELEEKMVSLLQEKNDLQL---Q 894
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
++ ++L + E++ L KV+++ E LE+ EE + K +
Sbjct: 895 VQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSL 954
Query: 124 NRMCKVLE---NRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE----DEL 176
R LE + ++++ + L E E+ K + + L D+L
Sbjct: 955 KRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDL 1014
Query: 177 EVAEDRVKSGDAKI-SELEEELKVVGNSL---KSLEVSEEKANQRVE 219
+V ED+V +G KI ++LE++ + SL K L E+A +++E
Sbjct: 1015 QVEEDKV-NGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLE 1060
Score = 48.8 bits (111), Expect = 2e-05
Identities = 38/212 (17%), Positives = 92/212 (43%), Gaps = 7/212 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M A+++ + + EK + + +Q D + +KVN ++ + KL Q +DL
Sbjct: 986 MTALEENISKLTKEKKSLQEAH---QQTLDDLQVEEDKVNGLIK-INAKLEQQTDDL--- 1038
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ LEQ K + E+ E ++ + +E + ++ EE+ + +L + Q
Sbjct: 1039 EGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENEKQQIEEKLKKKEFELSQLQARI 1098
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
D+ + + ++ + R+++L +++ L + + +++R+L + + LE A
Sbjct: 1099 DDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEAS 1158
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
+ + E E + + L+ + E
Sbjct: 1159 GATSAQIEMNKKREAEFQKMRRDLEEATLQHE 1190
Score = 48.4 bits (110), Expect = 3e-05
Identities = 36/182 (19%), Positives = 76/182 (41%), Gaps = 1/182 (0%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
QQ + + E+ + + L D L + + E+ + E ++ L+ +EVA
Sbjct: 1314 QQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVA 1373
Query: 87 ALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
K + + E+ EE Q+L EA++ + N C LE Q+ + ++ L
Sbjct: 1374 QWKTKYETDAIQRTEELEEAKKKLAQRLQEAEEKTETANSKCASLEKTKQRLQGEVEDLM 1433
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
L+ + D K + LA + +L+ ++ +++ + L EL + N+ +
Sbjct: 1434 RDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYE 1493
Query: 206 SL 207
+
Sbjct: 1494 EV 1495
Score = 45.6 bits (103), Expect = 2e-04
Identities = 34/171 (19%), Positives = 75/171 (43%), Gaps = 3/171 (1%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
E+ + L KK ++ L K KL+++ +LE +K+ + E+ + +++
Sbjct: 1437 ERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVV 1496
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
+ LE + Q+++ + + E + + E + E+ L L+E E
Sbjct: 1497 DQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLE 1556
Query: 157 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSL 207
+ K V +L+ V+ EL + +V D +I +L+ + +L+S+
Sbjct: 1557 HEESKILRVQLELSQVKSEL---DRKVIEKDEEIEQLKRNSQRAAEALQSV 1604
Score = 44.8 bits (101), Expect = 3e-04
Identities = 43/200 (21%), Positives = 100/200 (50%), Gaps = 29/200 (14%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
++ ++ M+ + +D+ +T ++ ++ + E++ E K L + E+ L +
Sbjct: 1480 SLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQ 1539
Query: 63 K-------LEQANKDLEEKEKQLTATEAEV----AALNRKVQQIEEDLE---KSEERSGT 108
+ LE+ LE +E ++ + E+ + L+RKV + +E++E ++ +R+
Sbjct: 1540 EKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAE 1599
Query: 109 AQQKLLEAQ-QSADENNRMCKVLE-------------NRAQQDEER-MDQLTNQLKEARL 153
A Q +L+A+ +S ++ R+ K +E NR + +R + + QLK+++L
Sbjct: 1600 ALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQRHLRTVQGQLKDSQL 1659
Query: 154 LAEDADGKSDEVSRKLAFVE 173
+DA ++++ +LA VE
Sbjct: 1660 HLDDALRSNEDLKEQLAIVE 1679
Score = 44.0 bits (99), Expect = 6e-04
Identities = 49/208 (23%), Positives = 90/208 (43%), Gaps = 11/208 (5%)
Query: 9 QAMKLEKDNAMDKADT-CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
Q K E A+ KA++ Q A + EE+ E +KKLAQ ++ + K E A
Sbjct: 1355 QEAKAELQRALSKANSEVAQWKTKYETDAIQRTEELEEAKKKLAQRLQEA---EEKTETA 1411
Query: 68 NKDLEEKEKQLTATEAEVAALNRKVQQIEE---DLEKSEERSGTA----QQKLLEAQQSA 120
N EK + EV L R +++ L+K + +QKL E+Q
Sbjct: 1412 NSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAEL 1471
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ + + L + +++ +QL+ R ++ + +++ ++A L+ AE
Sbjct: 1472 EAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAE 1531
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE 208
K + + S+L+ L+ V SL+ E
Sbjct: 1532 KTKKLVEQEKSDLQVALEEVEGSLEHEE 1559
Score = 41.5 bits (93), Expect = 0.003
Identities = 42/223 (18%), Positives = 104/223 (46%), Gaps = 8/223 (3%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQ-QARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
A+++ + +L + +D +D + +++ +L K E ++ + A+VE + ++
Sbjct: 1695 ALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEA-DIAQCQAEVENSIQESR 1753
Query: 62 NKLEQANK---DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA-- 116
N E+A K D ++L + A L R + +E+ ++ + R A+Q L+
Sbjct: 1754 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1813
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
+Q NR+ + LEN +++R + + ++ +++E + + ++D +
Sbjct: 1814 KQIQKLENRV-RELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDRKNILRLQDLV 1872
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ + +VKS + E EE+ + + ++ E+A +R +
Sbjct: 1873 DKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERAD 1915
Score = 38.3 bits (85), Expect = 0.030
Identities = 49/237 (20%), Positives = 110/237 (46%), Gaps = 27/237 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRAEKVNEEVRELQKKLAQVEEDLI 58
MD +K Q +E+ + + + QAR D + + + ++++ELQ ++ ++EE++
Sbjct: 1071 MDLENEKQQ---IEEKLKKKEFELSQLQARIDDEQVHSLQFQKKIKELQARIEELEEEIE 1127
Query: 59 LN---KNKLEQANKDL--------EEKEKQLTATEAEVAALNRK----VQQIEEDLEKSE 103
+ K+E+ DL E E+ AT A++ +N+K Q++ DLE++
Sbjct: 1128 AEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIE-MNKKREAEFQKMRRDLEEAT 1186
Query: 104 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 163
+ L + Q AD + + ++N Q+ ++++++ ++LK + +D +
Sbjct: 1187 LQHEATAATLRKKQ--ADSVAELGEQIDN-LQRVKQKLEKEKSELK---MEIDDMASNIE 1240
Query: 164 EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+S+ + +E ED+ AK + + + + L+ + + RVEE
Sbjct: 1241 ALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEE 1297
Score = 31.5 bits (68), Expect = 3.5
Identities = 44/212 (20%), Positives = 84/212 (39%), Gaps = 19/212 (8%)
Query: 73 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 132
E EK++ A + ++ +E+L +SE R ++K++ Q ++ +
Sbjct: 848 EAEKEM-------ATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETE 900
Query: 133 RAQQDEERMDQLTNQ--LKEARL--LAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDA 188
EER + L L EA++ L E + + +E++ +L + L ED+ S
Sbjct: 901 NLMDAEERCEGLIKSKILLEAKVKELTERLE-EEEEMNSELVAKKRNL---EDKCSSLKR 956
Query: 189 KISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKK 248
I +LE L V K +E K EE +T+
Sbjct: 957 DIDDLELTLTKVE---KEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDD 1013
Query: 249 LQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
LQ E D++ + IN + + D+++ + +
Sbjct: 1014 LQVEEDKVNGLIKINA-KLEQQTDDLEGSLEQ 1044
>AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein.
Length = 1116
Score = 64.1 bits (149), Expect = 5e-10
Identities = 52/281 (18%), Positives = 117/281 (41%), Gaps = 8/281 (2%)
Query: 11 MKLEKDNAMDKA-DTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
MK K ++M++ E++ + EE E K++ KNK+EQ +
Sbjct: 386 MKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKE 445
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV 129
+L KE Q + + A L ++ Q++++L + + Q KL ++ + +V
Sbjct: 446 ELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEV 505
Query: 130 LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED-------ELEVAEDR 182
L+ E+R L ++ RL E+ + ++ ++++ + + E+ +D
Sbjct: 506 LKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDM 565
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXX 242
+ + K++ L+++++ + L+ E +RV+
Sbjct: 566 LDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEK 625
Query: 243 XKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAG 283
+T+++L+++ DR E E D YK ++ + L G
Sbjct: 626 ERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQG 666
Score = 61.3 bits (142), Expect = 4e-09
Identities = 47/224 (20%), Positives = 101/224 (45%), Gaps = 5/224 (2%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++K+ ++ + +N ++ E+Q R + + + L +EE L
Sbjct: 566 LDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEK 625
Query: 61 KNKL----EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+ + EQ ++D EK++++ + ++ L KV ++ DL + E ++
Sbjct: 626 ERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSL 685
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
S + + K LE +Q +E ++ +QLK+A A +A S E+S ++ +E E+
Sbjct: 686 ASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARA-SPEMSDRIQHLEREI 744
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+D A++ L E LK V N + + ++V++
Sbjct: 745 TRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKD 788
Score = 48.8 bits (111), Expect = 2e-05
Identities = 51/210 (24%), Positives = 97/210 (46%), Gaps = 15/210 (7%)
Query: 13 LEKDNAMDKADTCEQQARDANLRA--EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKD 70
LE++ K ++ + QA L ++V E + KK+A++E + ++NK K
Sbjct: 740 LEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQ-VKDQNKKVANLKH 798
Query: 71 LEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
E+ EK+ +A E A LN QQ+++ L K ++R ++ L E+ Q E
Sbjct: 799 KEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREM 858
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
+ E+ E+++++L +++ + E K + LA E E + R +
Sbjct: 859 VLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLA--EKETHLTNLRAE- 915
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKAN 215
+ LEE L++ +L + +SE+ AN
Sbjct: 916 ---RRKHLEEVLEMKQEALLAA-ISEKDAN 941
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/241 (16%), Positives = 104/241 (43%), Gaps = 14/241 (5%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
E + ++ +++ L +EE++ + K+ + ++ EE+ KQ+ + + KV+Q++
Sbjct: 385 EMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLK 444
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
E+L E + ++K Q + + + + +++ LTNQ +++ E
Sbjct: 445 EELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIE 504
Query: 157 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
++ A ++ E++ R++ + +++ ++++ +++EEK Q
Sbjct: 505 VLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQ---------DMAEEKGTQ 555
Query: 217 RVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
E K ++ LQ+++ E ++ K+R KSL + +
Sbjct: 556 AGE-----IHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTN 610
Query: 277 T 277
T
Sbjct: 611 T 611
Score = 45.6 bits (103), Expect = 2e-04
Identities = 44/227 (19%), Positives = 91/227 (40%), Gaps = 11/227 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K+++ E K +T Q D+ E + E + +++ A ++ ++ + +
Sbjct: 471 VKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLR 530
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
LE+ L +K KQ+ E ++ +++ L+ E + Q+K+ Q+ +
Sbjct: 531 LEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDK 590
Query: 124 NRMCKVLENRA---QQDEERMDQLTNQLKEA--------RLLAEDADGKSDEVSRKLAFV 172
+ L+ R Q D D L+EA L E D E ++
Sbjct: 591 EKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNY 650
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ +L+ +++V +SE E L + SL S K + R++
Sbjct: 651 KKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLK 697
Score = 41.9 bits (94), Expect = 0.002
Identities = 46/261 (17%), Positives = 112/261 (42%), Gaps = 13/261 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D KK ++ +K EK + + + D E++A +L+ + L+K ++ L
Sbjct: 647 IDNYKKDLKDLK-EKVSLL-QGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALE 704
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAA-LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
+ K E + + K+ A EA + ++ ++Q +E ++ + ++ S AQ ++
Sbjct: 705 QKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEV------ 758
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
D + K +EN ++++ +L Q+K+ + K +K A + +E
Sbjct: 759 -DRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRR 817
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
ED + +L++ L+ + ++ LE + ++ Q E
Sbjct: 818 EDNLNDSS---QQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQV 874
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
++K+++E++ ++ +L
Sbjct: 875 EELLMAMEKVKQELESMKAKL 895
Score = 39.9 bits (89), Expect = 0.010
Identities = 46/206 (22%), Positives = 87/206 (42%), Gaps = 9/206 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D + + ++ ++ EK++ K E+Q +D N + + + + +KK AQ+ E+
Sbjct: 758 VDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRR 817
Query: 61 KNKLEQANKDLEEK-EKQLTATEAEVAALNRKVQ-QIEEDLEKSEERSGTAQ-----QKL 113
++ L +++ L++ K+ E AL VQ E ++ ++E S ++L
Sbjct: 818 EDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEEL 877
Query: 114 LEAQQSADENNRMCKVLENRAQQD-EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 172
L A + + K + QQ E+ LTN E R E+ E + A
Sbjct: 878 LMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQE-ALLAAIS 936
Query: 173 EDELEVAEDRVKSGDAKISELEEELK 198
E + +A + S K E LK
Sbjct: 937 EKDANIALLELSSSKKKTQEEVAALK 962
Score = 38.7 bits (86), Expect = 0.023
Identities = 31/170 (18%), Positives = 77/170 (45%), Gaps = 3/170 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q +A R + +N+ ++LQ L + ++ + + L ++ + E+E L E+
Sbjct: 809 QMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESART 868
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
++V+++ +EK ++ + + KL QQS E L ++ E + ++
Sbjct: 869 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQ 928
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 196
+ A + +DA+ E+S ++E+ + + D + +L+++
Sbjct: 929 EALLAAISEKDANIALLELSSSKKKTQEEVAALK---REKDRLVQQLKQQ 975
Score = 37.1 bits (82), Expect = 0.070
Identities = 44/185 (23%), Positives = 86/185 (46%), Gaps = 23/185 (12%)
Query: 36 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI 95
AE E + L + + ++L L + K LEE E ++ E + LN + + I
Sbjct: 260 AELTEENFQRLHAEHERQAKELFLLR-------KTLEEMELRI---ETQKQTLNARDESI 309
Query: 96 EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL-KEARLL 154
++ LE Q K L A+ + +++ R ++ E A+ ++ L Q KE +L
Sbjct: 310 KKLLE-------MLQSKGLSAKATEEDHERTRRLAE--AEMHVHHLESLLEQKEKENSML 360
Query: 155 AEDADGKSDEV--SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV-GNSLKSLEVSE 211
E+ + + S K ++ +E+ + ++ S + + +LEEE++++ N S E E
Sbjct: 361 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE 420
Query: 212 EKANQ 216
E+ Q
Sbjct: 421 EEMKQ 425
>S67240-1|AAB28951.1| 330|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 330
Score = 63.3 bits (147), Expect = 9e-10
Identities = 53/228 (23%), Positives = 101/228 (44%), Gaps = 11/228 (4%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQVEEDLILNK 61
AIK+ + KD + D + +RD K NE+ + L+ L Q++EDL +
Sbjct: 1 AIKQLRKLQAQMKDFQRELEDA--RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE 58
Query: 62 NKLEQANKDLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
+QA+ + EE ++L A + E L ++ Q+EE+LE+ + ++
Sbjct: 59 RARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 118
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK-SDEVSRKLAFVE 173
+A Q A++ + AQ++E QL Q KE R + +G + +A +E
Sbjct: 119 KATQQAEQLSNELATERTTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 178
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
++ E++V+ + + LK LK + + E + E++
Sbjct: 179 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY 226
Score = 58.0 bits (134), Expect = 3e-08
Identities = 42/185 (22%), Positives = 84/185 (45%), Gaps = 3/185 (1%)
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
+ L K + + Q++L +A+ S DE K E +A+ E + QL L A +
Sbjct: 3 KQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 62
Query: 157 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
AD + +E++ +LA +D + +A+I++LEEEL+ +++++ KA Q
Sbjct: 63 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 122
Query: 217 RVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
+ E+ + K+L+ ++ +E G K ++KS +++
Sbjct: 123 QAEQLSNELATERTTAQKNESARQQLERQNKELRSKLHEME---GAVKSKFKSTIAALEA 179
Query: 277 TFAEL 281
A+L
Sbjct: 180 KIAQL 184
Score = 53.2 bits (122), Expect = 1e-06
Identities = 45/222 (20%), Positives = 104/222 (46%), Gaps = 11/222 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 92 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERTTAQKNESA---RQQ 147
Query: 64 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 148 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 207
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
E + A+Q +E+ ++ +K+ + E+A+ +S ++ ++ EL+
Sbjct: 208 KLKEILLQVEDERKMAEQYKEQAEKGNAGVKQLKRQLEEAEEESQRINANRRKLQRELDE 267
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
A + ++ +++ L+ +L+ GN S S +RV E
Sbjct: 268 ATESNEAMGREVNALKSKLR-RGNE-TSFVPSRRSGGRRVIE 307
>BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containing
linker protein 1 protein.
Length = 1392
Score = 63.3 bits (147), Expect = 9e-10
Identities = 47/212 (22%), Positives = 107/212 (50%), Gaps = 15/212 (7%)
Query: 12 KLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDL 71
K ++ +D D + + + +K+ +++ +K++ +E + +K ++L
Sbjct: 721 KATEEKLLD-LDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITREL 779
Query: 72 EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE 131
+ +E +LT + ++ +V Q++E LEK + ++K EA + A R +
Sbjct: 780 QGRELKLTNLQENLS----EVSQVKETLEKELQ---ILKEKFAEASEEAVSVQRSMQETV 832
Query: 132 NRAQQDEERMDQLTNQLKEARLLAEDADGK---SDEVSRKLAFVEDELE--VAEDRVKSG 186
N+ Q EE+ + L++ L++ R D + K DE +L +++LE +AE SG
Sbjct: 833 NKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSG 892
Query: 187 D--AKISELEEELKVVGNSLKSLEVSEEKANQ 216
D ++++++ +EL++ ++ L++ KAN+
Sbjct: 893 DNSSQLTKMNDELRLKERDVEELQLKLTKANE 924
Score = 60.5 bits (140), Expect = 7e-09
Identities = 44/228 (19%), Positives = 103/228 (45%), Gaps = 8/228 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A +K+++ +++EK+ KA + ++ + L+ + E + E+ + +E++L +
Sbjct: 751 LEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQIL 810
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K K +A+++ ++ + T ++ + + DLEK E + K E +
Sbjct: 811 KEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDERE 870
Query: 121 DENNRMCKVLENR----AQQDEERMDQLTNQLKEARLLAEDADG---KSDEVSRKLAFVE 173
++ + + LEN + + QLT E RL D + K + + +F++
Sbjct: 871 EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQ 930
Query: 174 DELEVAEDRVKSGDAKISEL-EEELKVVGNSLKSLEVSEEKANQRVEE 220
+E + + + ++ EEE K + L LE E ++ + +E
Sbjct: 931 KSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQE 978
Score = 56.0 bits (129), Expect = 1e-07
Identities = 46/223 (20%), Positives = 97/223 (43%), Gaps = 14/223 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQAR----DANLRAEKVNEEVRELQK---KLAQV 53
+DA++K K E + + E+Q + + N + K + RELQ KL +
Sbjct: 730 LDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNL 789
Query: 54 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
+E+L E K+L+ +++ E ++ R +Q+ L + EE+ L
Sbjct: 790 QENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDL 849
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
+ +++ + + + R +Q + ++L N + E ++ D S +L +
Sbjct: 850 EKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDN-------SSQLTKMN 902
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
DEL + E V+ K+++ E + S++ + V E++ Q
Sbjct: 903 DELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQ 945
Score = 51.2 bits (117), Expect = 4e-06
Identities = 50/274 (18%), Positives = 112/274 (40%), Gaps = 14/274 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M+A++ K+ + EK+N+++ + +A D +L ++ + + +LQ+ +V+E +L
Sbjct: 646 MEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHL--VEMEDTLNKLQEAEIKVKELEVL- 702
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ K + K ++ Q ATE ++ ++ D + G ++ K L Q A
Sbjct: 703 QAKCNEQTKVIDNFTSQPKATEEKL---------LDLDALRKASSEGKSEMKKLRQQLEA 753
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
E + K LE + + +T +L+ L + EVS+ +E EL++ +
Sbjct: 754 AE--KQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILK 811
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
++ + ++ ++ N L E + +E+
Sbjct: 812 EKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREE 871
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
K +KL+ ++ + G N + + DE+
Sbjct: 872 QLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDEL 905
Score = 46.4 bits (105), Expect = 1e-04
Identities = 44/214 (20%), Positives = 88/214 (41%), Gaps = 7/214 (3%)
Query: 12 KLEKDNA--MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
KLE D A M + Q N +V ELQ KL + E+ + +E
Sbjct: 879 KLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTV 938
Query: 70 DLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
E+ +++ E E L RK+ +E+ +E S + + + A +++ + +
Sbjct: 939 KAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERA--TSETKTKHEE 996
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADG--KSDEVSRKLAFVEDELEVAEDRVKSG 186
+L+N + + D+L +E L ++ + K + ++ ED +++ E K
Sbjct: 997 ILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEK 1056
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
++ LE+ + L+ +E + VEE
Sbjct: 1057 TETLASLEDTKQTNAKLQNELDTLKENNLKNVEE 1090
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/224 (19%), Positives = 105/224 (46%), Gaps = 16/224 (7%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAE--------KVNEEVRELQKKLAQVEED 56
++ ++ ++L+ A + A ++ D ++AE K EE +EL++KL+ +E+
Sbjct: 909 ERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKK 968
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAA-LNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ + N+ ++ E + E+ L + + E+ L+ + E + Q+L E
Sbjct: 969 METSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEE 1028
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL-AFVED 174
++ AD+ K + A+ + M+Q+T + E ED + ++ +L E+
Sbjct: 1029 LRKQADK----AKAAQT-AEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKEN 1083
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
L+ E+ KS + E ++++ +++L+ + + +Q++
Sbjct: 1084 NLKNVEELNKSKELLTVE-NQKMEEFRKEIETLKQAAAQKSQQL 1126
Score = 44.0 bits (99), Expect = 6e-04
Identities = 44/249 (17%), Positives = 104/249 (41%), Gaps = 8/249 (3%)
Query: 42 EVRELQKKLAQVEEDLILNKNKLE-QANKDLEEKEKQLTATEAEVAALNRK----VQQIE 96
E EL+ ++ ++ D L+ Q N + K++ A A++ + ++ ++ I
Sbjct: 609 EFAELKTQIEKMRLDYQHEIENLQNQQNSERAAHAKEMEALRAKLMKVIKEKENSLEAIR 668
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK--EARLL 154
L+K+E++ + L Q A+ + +VL+ + + + +D T+Q K E +LL
Sbjct: 669 SKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQPKATEEKLL 728
Query: 155 AEDADGK-SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
DA K S E ++ + +LE AE ++K + + + + + L+ E+
Sbjct: 729 DLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTN 788
Query: 214 ANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADE 273
+ + E + +Q+ + ++L ++++ L+ +
Sbjct: 789 LQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSD 848
Query: 274 MDSTFAELA 282
++ LA
Sbjct: 849 LEKLRENLA 857
Score = 42.3 bits (95), Expect = 0.002
Identities = 39/185 (21%), Positives = 85/185 (45%), Gaps = 9/185 (4%)
Query: 20 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 79
DKA Q A DA E++ +E E L ++ +N+L+ ++ + ++L
Sbjct: 1034 DKAKAA-QTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELN 1092
Query: 80 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS----ADENNRMCKVLENRAQ 135
++ + N+K+++ +++E ++ + Q+L Q+ A+E R + + +
Sbjct: 1093 KSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQK 1152
Query: 136 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 195
+EER L NQL E + +DE + A ++ + + + DA++ +L
Sbjct: 1153 LEEER-SVLNNQLLEMKKRESKFIKDADE---EKASLQKSISITSALLTEKDAELEKLRN 1208
Query: 196 ELKVV 200
E+ V+
Sbjct: 1209 EVTVL 1213
Score = 41.9 bits (94), Expect = 0.002
Identities = 42/211 (19%), Positives = 94/211 (44%), Gaps = 7/211 (3%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
M+ M EK + + +Q + + E + ++L + +E L + K+E+
Sbjct: 1049 MEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEF 1108
Query: 68 NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMC 127
K++E ++ +++AL + ++ E+L +S + T+ QKL E + +
Sbjct: 1109 RKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEV-TSHQKLEEERSVLNNQLLEM 1167
Query: 128 KVLENRAQQD-EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
K E++ +D +E L + L + D + +++ ++ + E A KS
Sbjct: 1168 KKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASA----KSL 1223
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQR 217
+ + LE + + +K+LE+ + K N+R
Sbjct: 1224 HSVVQTLESDKVKLELKVKNLEL-QLKENKR 1253
Score = 37.5 bits (83), Expect = 0.053
Identities = 41/136 (30%), Positives = 65/136 (47%), Gaps = 21/136 (15%)
Query: 76 KQLTATEAEVAALNRKVQQIEE-----DLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
++++ T A AL K Q IE+ DLE++E T+ +E + + + VL
Sbjct: 345 RKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVL 404
Query: 131 ENRAQQDE-----ERMD----QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E A+ D+ E D +L NQL+E + ED + +E S + +LEVA
Sbjct: 405 ELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEES----ITKGDLEVATV 460
Query: 182 RVKSGDAKISELEEEL 197
KS +I ELE++L
Sbjct: 461 SEKS---RIMELEKDL 473
Score = 35.5 bits (78), Expect = 0.21
Identities = 50/274 (18%), Positives = 116/274 (42%), Gaps = 11/274 (4%)
Query: 12 KLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDL 71
++E++ A+ + D +Q + + +++ V ++ ++ L K K+E +
Sbjct: 387 EIEQELALAR-DGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRV 445
Query: 72 EEKEKQLTATEAEVAALNRK--VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV 129
EE+ +T + EVA ++ K + ++E+DL + +++ LE+ + A + + +
Sbjct: 446 EEES--ITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRR-LESNKPAGDVDMSLSL 502
Query: 130 LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAK 189
L+ + E+ T+ +E L E + + +++ + E +S +K
Sbjct: 503 LQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSK 562
Query: 190 ISELEEELKVVGNSLKS-LEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVK- 247
+ +E V KS LE + Q +EE + ++
Sbjct: 563 LEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGAETAEFAELKTQIEKMRL 622
Query: 248 KLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
Q E++ L+++ N +R + A EM++ A+L
Sbjct: 623 DYQHEIENLQNQQ--NSER-AAHAKEMEALRAKL 653
>D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 62.9 bits (146), Expect = 1e-09
Identities = 68/294 (23%), Positives = 125/294 (42%), Gaps = 24/294 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN----EEVRELQKKLAQVE-- 54
+ +K+K++ K E +D + +Q A EKV+ ++ E + KL + +
Sbjct: 1212 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRS 1271
Query: 55 -EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQ 110
D + KL+ N +L +QL EA ++ L R Q EDL++ E G A+
Sbjct: 1272 LNDFTTQRAKLQTENGEL---SRQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAK 1328
Query: 111 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKS 162
L A QSA + C +L + +++ E +L L +A +A+ DA ++
Sbjct: 1329 NALAHALQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQCRTKYETDAIQRT 1385
Query: 163 DEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFX 222
+E+ + L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1386 EELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALD 1445
Query: 223 XXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
++ QKE L EL K+ Y+ + +++
Sbjct: 1446 KKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1499
Score = 62.5 bits (145), Expect = 2e-09
Identities = 48/210 (22%), Positives = 110/210 (52%), Gaps = 13/210 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKKM A ++ E + A+ + E++A+ A A + EE+++ Q A +E +
Sbjct: 1729 KKKMDADLSQLQSEVEEAVQECRNAEEKAKKAITHAAMMAEELKKEQDTSAHLER---MK 1785
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E +LE ++R+ + + + +
Sbjct: 1786 KN-MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRK 1844
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
+++ E + + + ++ +D+L ++K + AE+A+ +++ K V+ E
Sbjct: 1845 SERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 1904
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLK 205
L+ AE+R ++++++L + + +G K
Sbjct: 1905 LDEAEERADIAESQVNKLRAKSRDIGAKQK 1934
Score = 56.8 bits (131), Expect = 8e-08
Identities = 56/276 (20%), Positives = 118/276 (42%), Gaps = 19/276 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 59
++ ++K+++ KLE +A+++A+ + LRA+ + N+ E+++KLA+ +E++
Sbjct: 1528 LEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 1587
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGTAQQK--- 112
K ++ L+ T + EV + +K++ ++E L + + AQ++
Sbjct: 1588 AKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS 1647
Query: 113 ----LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED-------ADGK 161
L + Q D+ R L+ E R + L +L+E R + E AD +
Sbjct: 1648 LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADRE 1707
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
E S ++ + + ++ K DA +S+L+ E++ ++ E +KA
Sbjct: 1708 LIETSERVQLLHSQNTSLINQKKKMDADLSQLQSEVEEAVQECRNAEEKAKKAITHAAMM 1767
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLE 257
+T+K LQ +D E
Sbjct: 1768 AEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 1803
Score = 54.0 bits (124), Expect = 6e-07
Identities = 45/214 (21%), Positives = 99/214 (46%), Gaps = 12/214 (5%)
Query: 11 MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE----Q 66
++ E+DN D + C+Q ++ ++ E +E+ E + ++ +L K KLE +
Sbjct: 893 VQAEQDNLNDAEERCDQLIKN-KIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSE 951
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
KD+++ E L E E A KV+ + E++ +E KL + +++ E ++
Sbjct: 952 LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDE----IIAKLTKEKKALQEAHQ- 1006
Query: 127 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
+ L++ Q +E++++ L+ + +D +G ++ + +E E +K
Sbjct: 1007 -QALDD-LQAEEDKVNTLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLT 1064
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
I +LE + + LK E + N ++E+
Sbjct: 1065 QESIMDLENDKLQLEEKLKKKEFDINQQNSKIED 1098
Score = 52.8 bits (121), Expect = 1e-06
Identities = 42/192 (21%), Positives = 86/192 (44%), Gaps = 4/192 (2%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1424 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1483
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
L ++ E LE + + Q+++ + + E + LE +Q E +L
Sbjct: 1484 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQ 1543
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
+ L+EA E +GK + +L F + + E+ E ++ D ++ + + + V +SL+
Sbjct: 1544 SALEEAEASLEHEEGKI--LRAQLEFNQIKAEI-ERKLAEKDEEMEQAKRNHQRVVDSLQ 1600
Query: 206 -SLEVSEEKANQ 216
SL+ N+
Sbjct: 1601 TSLDAETRSRNE 1612
Score = 52.0 bits (119), Expect = 2e-06
Identities = 60/274 (21%), Positives = 115/274 (41%), Gaps = 20/274 (7%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDA---NLRAE-KVNEEVRELQKKLAQVEEDLIL 59
IK +++ EKD M++A Q+ D+ +L AE + EV ++KK+ E DL
Sbjct: 1570 IKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKM---EGDLNE 1626
Query: 60 NKNKLEQANKDLEEKEKQLTA-------TEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
+ +L AN+ E +KQ+ + T+ ++ R ++E++ E R+ Q +
Sbjct: 1627 MEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 1686
Query: 113 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 172
L E + ++ R K+ + + ER+ L +Q + D ++ ++
Sbjct: 1687 LEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQSEVEEA 1746
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXX 232
E AE++ K + + EELK ++ LE ++ Q +++
Sbjct: 1747 VQECRNAEEKAKKAITHAAMMAEELKKEQDTSAHLERMKKNMEQTIKDL------QHRLD 1800
Query: 233 XXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
K ++KL+ V LE EL + R
Sbjct: 1801 EAEQIALKGGKKQLQKLEARVRELEGELEAEQKR 1834
Score = 50.8 bits (116), Expect = 5e-06
Identities = 38/170 (22%), Positives = 83/170 (48%), Gaps = 7/170 (4%)
Query: 45 ELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 104
E +K++A ++E+ K LE++ +E E+++ + E L +VQ +++L +EE
Sbjct: 846 ETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEE 905
Query: 105 RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 164
R + ++ + E N R + +EE +LT + ++ + D+
Sbjct: 906 RCDQLIKNKIQLEAKVKEMNE-------RLEDEEEMNAELTAKKRKLEDECSELKKDIDD 958
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
+ LA VE E E++VK+ +++ L+E + + K+L+ + ++A
Sbjct: 959 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 1008
Score = 50.4 bits (115), Expect = 7e-06
Identities = 45/261 (17%), Positives = 110/261 (42%), Gaps = 8/261 (3%)
Query: 5 KKKMQAMKLEKDNAMDKADT-CEQQARDANLRAEKVNEEVRELQK---KLAQVEEDLILN 60
+ K + +++ +++A Q+ +DA E VN + L+K +L EDL+++
Sbjct: 1374 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1433
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ A L++K++ AE +K ++ + +LE S++ + + +L + + +
Sbjct: 1434 VERSNAAAAALDKKQRNFDKILAE---WKQKYEESQSELESSQKEARSLSTELFKLKNAY 1490
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+E+ + + + +E + LT QL E + + ++ + ++ LE AE
Sbjct: 1491 EESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAE 1550
Query: 181 DRVKSGDAKISELEEELKVVGNSL-KSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
++ + KI + E + + + L +E+ Q
Sbjct: 1551 ASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSR 1610
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
+ KK++ +++ +E +L
Sbjct: 1611 NEVLRVKKKMEGDLNEMEIQL 1631
Score = 50.0 bits (114), Expect = 9e-06
Identities = 59/293 (20%), Positives = 131/293 (44%), Gaps = 20/293 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++ + ++ EK +K ++ + K+ +E + LQ+ Q +DL
Sbjct: 956 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE 1015
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
++K+ +K + E+Q+ E + + +++ DLE++ +R KL +
Sbjct: 1016 EDKVNTLSKSKVKLEQQVDDLEGSL----EQEKKVRMDLERA-KRKLEGDLKLTQESIMD 1070
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
EN+++ LE + ++ E ++Q +++++ ++LA K E ++ +E+ELE AE
Sbjct: 1071 LENDKL--QLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELE-AE 1127
Query: 181 DRVKSGDAKI-SELEEELKVVGNSLK----SLEVSEEKANQRVEEFXXXXXXXXXXXXXX 235
++ K+ S+L EL+ + L+ + V E +R EF
Sbjct: 1128 RTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQH 1187
Query: 236 XXXXXXXXK----TVKKLQKEVD---RLEDELGINKDRYKSLADEMDSTFAEL 281
K +V +L +++D R++ +L K +K D++ S ++
Sbjct: 1188 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQI 1240
Score = 48.8 bits (111), Expect = 2e-05
Identities = 53/261 (20%), Positives = 117/261 (44%), Gaps = 15/261 (5%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++KM ++ EK++ + + DA R +++ + +L+ K+ ++ E L
Sbjct: 875 LEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERL----ED 930
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE-AQQSADE 122
E+ N +L K+++L E E + L + + +E L K E+ + K+ ++ A
Sbjct: 931 EEEMNAELTAKKRKL---EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 987
Query: 123 NNRMCKVL-ENRAQQD--EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+ + K+ E +A Q+ ++ +D L + + L++ +V +E E +V
Sbjct: 988 DEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLSKSKVKLEQQVDDLEGSLEQEKKVR 1047
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + AK +LE +LK+ S+ LE + + +++++
Sbjct: 1048 MDLER---AK-RKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLA 1103
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
K +K+ Q ++ LE+EL
Sbjct: 1104 LQLQKKLKENQARIEELEEEL 1124
Score = 39.5 bits (88), Expect = 0.013
Identities = 27/184 (14%), Positives = 88/184 (47%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K++ ++ +LQ ++ + ++ + K ++A ++L + A L R + +E
Sbjct: 1730 KKMDADLSQLQSEVEEAVQECRNAEEKAKKAITHAAMMAEELKKEQDTSAHLERMKKNME 1789
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LE + +++R + ++++
Sbjct: 1790 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRI 1849
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + L ++D ++ + +VK+ + E EE+ + + ++ ++A
Sbjct: 1850 KELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAE 1909
Query: 216 QRVE 219
+R +
Sbjct: 1910 ERAD 1913
Score = 31.1 bits (67), Expect = 4.6
Identities = 50/271 (18%), Positives = 107/271 (39%), Gaps = 26/271 (9%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNE--EVRELQKKLAQVEEDLILNKN 62
K++ + K+ +D +++A T + +A A LR + + E+ E L +V++ L K+
Sbjct: 1168 KREAEFQKMRRD--LEEA-TLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1224
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSAD 121
+ + D+ +Q+ +A + ++R ++ Q E K EE + + +
Sbjct: 1225 EFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQT 1284
Query: 122 ENNRMCKVLENRAQ----------QDEERMDQLTNQLKEARLLAEDADGKS-DEVSRKLA 170
EN + + LE + ++M+ L QL+E +GK+ + ++ L
Sbjct: 1285 ENGELSRQLEEKEALISQLTRGKLSYTQQMEDLKRQLEE--------EGKAKNALAHALQ 1336
Query: 171 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVS-EEKANQRVEEFXXXXXXXX 229
+ ++ ++ + +EL+ L + + E A QR EE
Sbjct: 1337 SARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQCRTKYETDAIQRTEELEEAKKKLA 1396
Query: 230 XXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
L+K RL++E+
Sbjct: 1397 QRLQDAEEAVEAVNAKCSSLEKTKHRLQNEI 1427
>BC129821-1|AAI29822.1| 315|Homo sapiens FLJ36144 protein protein.
Length = 315
Score = 62.9 bits (146), Expect = 1e-09
Identities = 41/174 (23%), Positives = 94/174 (54%), Gaps = 6/174 (3%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E++ R+ + + E++ +K+L + E++L + +L + K+L E+E+Q+ E ++
Sbjct: 26 EERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELRE-QKELREQEEQMQEQEEKM 84
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS-ADENNRMCKVLENRAQQDEERMDQL 144
K+++ EE + + EER ++++ E +Q D+ RM + + R ++ EERM +
Sbjct: 85 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWE-QDERLREKEERMREQ 143
Query: 145 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 198
++ + E+ K E +K E++++ E+R++ + K+ E EE ++
Sbjct: 144 EKMWEQVEKMREEK--KMQEQEKKTRDQEEKMQ-EEERIREREKKMREEEETMR 194
Score = 54.4 bits (125), Expect = 4e-07
Identities = 42/203 (20%), Positives = 95/203 (46%), Gaps = 11/203 (5%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E++ R+ + K E++ +++L + E + + K+ + K L E+EK+L E E+
Sbjct: 5 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKEL 64
Query: 86 ---AALNRKVQQIEEDLEK---SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 139
L + +Q++E EK EE+ ++K+ ++ E + + E + + EE
Sbjct: 65 REQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 124
Query: 140 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE---LEEE 196
RM + +L+E + + ++V + E +++ E + + + K+ E + E
Sbjct: 125 RMWEQDERLREKEERMREQEKMWEQVEKMRE--EKKMQEQEKKTRDQEEKMQEEERIRER 182
Query: 197 LKVVGNSLKSLEVSEEKANQRVE 219
K + +++ EEK ++ E
Sbjct: 183 EKKMREEEETMREQEEKMQKQEE 205
Score = 52.8 bits (121), Expect = 1e-06
Identities = 35/181 (19%), Positives = 88/181 (48%), Gaps = 6/181 (3%)
Query: 41 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 100
EE+RE +KK+ + EE + + +L + + E+E+++ E + +++++ E++L
Sbjct: 6 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELR 65
Query: 101 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+ +E ++++ E ++ E + E + + EER+ + Q++E D +
Sbjct: 66 EQKELR-EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 124
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE-KANQRVE 219
+ E +L E+ + E + ++ ++ EE K+ K+ + E+ + +R+
Sbjct: 125 RMWEQDERLREKEERMREQEKMWE----QVEKMREEKKMQEQEKKTRDQEEKMQEEERIR 180
Query: 220 E 220
E
Sbjct: 181 E 181
Score = 48.0 bits (109), Expect = 4e-05
Identities = 42/197 (21%), Positives = 94/197 (47%), Gaps = 8/197 (4%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKV----NEEVRELQKKLAQVEEDLILN 60
K + Q K+ + + E + ++ LR +K E+++E ++K+ + EE +
Sbjct: 35 KMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQ 94
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ K+ + + L E+EKQ+ E ++ ++ + +E L + EER Q+K+ E +
Sbjct: 95 EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM-REQEKMWEQVEKM 153
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
E +M + E + + EE+M Q +++E + + E K+ E+ + E
Sbjct: 154 REEKKM-QEQEKKTRDQEEKM-QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 211
Query: 181 DRVKSGDAKISELEEEL 197
++ + ++ E +E+L
Sbjct: 212 EK-EWQQQRLPEQKEKL 227
Score = 46.8 bits (106), Expect = 9e-05
Identities = 40/179 (22%), Positives = 91/179 (50%), Gaps = 6/179 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-QKKLAQVEEDLILNKN 62
++++ Q M+ +++ M + D ++ + EK+ E+V ++ ++K Q +E ++
Sbjct: 112 MREQEQKMR-DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQE 170
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+ Q + + E+EK++ E + K+Q+ EE++ + EE+ QQ+L E ++ E
Sbjct: 171 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE-WQQQRLPEQKEKLWE 229
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
+M + E +Q+E+ DQ +E ++ ++ + ++V A +D E ED
Sbjct: 230 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDVG---AGGDDAREGGED 285
>S73840-1|AAC13916.1| 231|Homo sapiens type IIA myosin heavy chain
protein.
Length = 231
Score = 62.5 bits (145), Expect = 2e-09
Identities = 50/213 (23%), Positives = 110/213 (51%), Gaps = 13/213 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKK++ M+ E ++ + +A E++A+ A A + EE+++ Q A +E +
Sbjct: 23 KKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 79
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E ++E ++R+ A + L +
Sbjct: 80 KN-MEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRK 138
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
++ E + + ++ +D+L ++K + AE+A+ +S+ K ++ E
Sbjct: 139 HERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHE 198
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
LE AE+R ++++++L + + V + S E
Sbjct: 199 LEEAEERADIAESQVNKLRVKSREVHTKVISEE 231
Score = 43.2 bits (97), Expect = 0.001
Identities = 30/184 (16%), Positives = 86/184 (46%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K+ ++ ++Q ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 24 KKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 83
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LE + +++R + L++
Sbjct: 84 QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRV 143
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + + ++D ++ + +VKS + E EE+ + L+ E+A
Sbjct: 144 KELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAE 203
Query: 216 QRVE 219
+R +
Sbjct: 204 ERAD 207
>M25142-1|AAA60387.1| 389|Homo sapiens myosin heavy chain
alpha-subunit protein.
Length = 389
Score = 62.5 bits (145), Expect = 2e-09
Identities = 48/210 (22%), Positives = 111/210 (52%), Gaps = 13/210 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKKM+A ++ E + A+ + E++A+ A A + EE+++ Q A +E +
Sbjct: 179 KKKMEADLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 235
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E +LE ++R+ + + + +
Sbjct: 236 KN-IEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRK 294
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
+++ E + + + ++ +D+L ++K + AE+A+ +++ K V+ E
Sbjct: 295 SERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 354
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLK 205
L+ AE+R ++++++L + + +G K
Sbjct: 355 LDEAEERADIAESQVNKLRAKSRDIGAKQK 384
Score = 48.8 bits (111), Expect = 2e-05
Identities = 49/281 (17%), Positives = 120/281 (42%), Gaps = 9/281 (3%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
+ + + ++++K D + E Q AN A + ++V+ LQ L +D + +
Sbjct: 58 RSRNEVLRVKKKMEGD-LNEMEIQLSHANRMAAEAQKQVKSLQSLL----KDTQIQLDDA 112
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
+AN DL+E + E L +++++ +E++E A ++L+E + +
Sbjct: 113 VRANDDLKE---NIAIVERRNNLLQAELEELRAVVEQTERSRKLADRELIETSERVQLLH 169
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
L N+ ++ E + QL ++++EA +A+ K+ + A + +EL+ +D
Sbjct: 170 SQNTSLINQKKKMEADLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSA 229
Query: 185 SGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXX 243
+ +E+ +K + + L E ++ + +++++
Sbjct: 230 HLERMKKNIEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESV 289
Query: 244 KTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K ++ + L + +K L D +D ++ Y
Sbjct: 290 KGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAY 330
Score = 48.4 bits (110), Expect = 3e-05
Identities = 42/266 (15%), Positives = 105/266 (39%), Gaps = 8/266 (3%)
Query: 18 AMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQ 77
A + + + +D ++ + +L++ +A VE L + +LE+ +E+ E+
Sbjct: 91 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 150
Query: 78 LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQD 137
+ E+ + +VQ + + + L + Q +E + C+ E +A++
Sbjct: 151 RKLADRELIETSERVQLLHSQNTSLINQKKKMEADLTQLQSEVEEAVQECRNAEEKAKKA 210
Query: 138 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED-RVKSG-------DAK 189
+ +LK+ + + + + + + ++ L+ AE +K G +A+
Sbjct: 211 ITDAAMMAEELKKEQDTSAHLERMKKNIEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 270
Query: 190 ISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKL 249
+ ELE EL+ K+ +R++E VK
Sbjct: 271 VRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAY 330
Query: 250 QKEVDRLEDELGINKDRYKSLADEMD 275
+++ + E++ N +++ + E+D
Sbjct: 331 KRQAEEAEEQANTNLSKFRKVQHELD 356
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/184 (15%), Positives = 88/184 (47%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K+ ++ +LQ ++ + ++ + K ++A D ++L + A L R + IE
Sbjct: 180 KKMEADLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNIE 239
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LE + +++R + ++++
Sbjct: 240 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRI 299
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + L ++D ++ + +VK+ + E EE+ + + ++ ++A
Sbjct: 300 KELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAE 359
Query: 216 QRVE 219
+R +
Sbjct: 360 ERAD 363
Score = 39.5 bits (88), Expect = 0.013
Identities = 38/162 (23%), Positives = 80/162 (49%), Gaps = 8/162 (4%)
Query: 54 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
EE IL + +LE N+ E E++L + E+ R Q++ + L+ S + ++ ++
Sbjct: 6 EEGKIL-RAQLE-FNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEV 63
Query: 114 LEAQQSADEN-NRMCKVLE--NR-AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
L ++ + + N M L NR A + ++++ L + LK+ ++ +DA +D++ +
Sbjct: 64 LRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENI 123
Query: 170 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSE 211
A VE + + ++ A + + E K+ L +E SE
Sbjct: 124 AIVERRNNLLQAELEELRAVVEQTERSRKLADREL--IETSE 163
>BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2,
skeletal muscle, adult protein.
Length = 1941
Score = 62.5 bits (145), Expect = 2e-09
Identities = 50/213 (23%), Positives = 110/213 (51%), Gaps = 13/213 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKK++ M+ E ++ + +A E++A+ A A + EE+++ Q A +E +
Sbjct: 1733 KKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 1789
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E ++E ++R+ A + L +
Sbjct: 1790 KN-MEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRK 1848
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
++ E + + ++ +D+L ++K + AE+A+ +S+ K ++ E
Sbjct: 1849 HERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHE 1908
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
LE AE+R ++++++L + + V + S E
Sbjct: 1909 LEEAEERADIAESQVNKLRVKSREVHTKVISEE 1941
Score = 58.4 bits (135), Expect = 3e-08
Identities = 50/226 (22%), Positives = 110/226 (48%), Gaps = 10/226 (4%)
Query: 4 IKKKMQA---MKLEKDNAMDKAD-TCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDL 57
IK K+Q +K + A D+ + E A+ L E ++ +++ +L+ LA+VE++
Sbjct: 915 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 974
Query: 58 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
+NK++ +++ ++ + E AL QQ +DL+ E++ T + ++ +
Sbjct: 975 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLE 1034
Query: 118 QSADENNRMCKVLENRAQQDEERMD-QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
Q D+ + E + + D ER +L LK A+ D + + ++ KL E E+
Sbjct: 1035 QQVDDLEGSLE-QEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEI 1093
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSL--EVSEEKANQRVEE 220
+ +++ A +L++++K + ++ L E+ E+A++ E
Sbjct: 1094 SNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAE 1139
Score = 50.4 bits (115), Expect = 7e-06
Identities = 51/226 (22%), Positives = 109/226 (48%), Gaps = 12/226 (5%)
Query: 1 MDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
++ K+K++ +KL +++ MD + E+Q D L+ ++ E+ LQ K+ + I
Sbjct: 1054 LERAKRKLEGDLKLAQESIMDIEN--EKQQLDEKLKKKEF--EISNLQSKIEDEQALGIQ 1109
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER---SGTAQQKLLEA 116
+ K+++ +EE E+++ A A A ++ + +LE+ ER +G A +E
Sbjct: 1110 LQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEM 1169
Query: 117 QQSAD-ENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVED 174
+ + E +M + LE Q E L + ++ L E D V +KL +
Sbjct: 1170 NKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQID-NLQRVKQKLEKEKS 1228
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
E+++ D + S +S+ + L+ + +L+ ++SE K+ + ++
Sbjct: 1229 EMKMEIDDLASNVETVSKAKGNLEKMCRTLED-QLSELKSKEEEQQ 1273
Score = 49.2 bits (112), Expect = 2e-05
Identities = 47/209 (22%), Positives = 99/209 (47%), Gaps = 15/209 (7%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+Q+ D + + + + EL+K QVE++ + LE+A LE +E ++ + E+
Sbjct: 1512 QQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLEL 1571
Query: 86 ----AALNRKVQQIEED---LEKSEERSGTAQQKLLEAQ-QSADENNRMCKVLENRAQQD 137
+ ++RK+ + +E+ L+++ R + Q L+A+ +S ++ R+ K +E +
Sbjct: 1572 NQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEM 1631
Query: 138 EERMDQLTNQLKEA-------RLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 190
E +++ EA + + +D D+ R ++++L + E R A+I
Sbjct: 1632 EIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEI 1691
Query: 191 SELEEELKVVGNSLKSLEVSEEKANQRVE 219
EL L+ S K E A++RV+
Sbjct: 1692 EELRATLEQTERSRKIAEQELLDASERVQ 1720
Score = 47.2 bits (107), Expect = 7e-05
Identities = 30/165 (18%), Positives = 79/165 (47%)
Query: 49 KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 108
K A+ E+++ K + ++ +L + E + E ++ L ++ ++ ++ E
Sbjct: 847 KSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906
Query: 109 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
A+++ + ++ + K + RA+ +EE +LT + ++ + D++
Sbjct: 907 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 966
Query: 169 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
LA VE E E++VK+ +++ L+E + + K+L+ + ++
Sbjct: 967 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQ 1011
Score = 46.8 bits (106), Expect = 9e-05
Identities = 68/291 (23%), Positives = 123/291 (42%), Gaps = 35/291 (12%)
Query: 12 KLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK-- 69
KLEK+ + K + D E V++ L+K +E+ L K+K E+ +
Sbjct: 1222 KLEKEKSEMK-----MEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLI 1276
Query: 70 -DLE-----------EKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQQKL 113
DL E +QL EA V+ L+R QQIEE L++ E A+ L
Sbjct: 1277 NDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE-LKRQLEEEIKAKNAL 1335
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEV 165
A QS+ + C +L + ++++E +L L +A +A+ DA +++E+
Sbjct: 1336 AHALQSSRHD---CDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEEL 1392
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXX 225
+ L+ AE+ V++ +AK + LE+ + + N ++ L + E+ N
Sbjct: 1393 EEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQ 1452
Query: 226 XXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
++ QKE L EL K+ Y+ D++++
Sbjct: 1453 RNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLET 1503
Score = 45.6 bits (103), Expect = 2e-04
Identities = 37/205 (18%), Positives = 94/205 (45%), Gaps = 7/205 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++ + ++ EK +K ++ + K+ +E + LQ+ Q +DL
Sbjct: 960 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAE 1019
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
++K+ K + E+Q+ E + + +++ DLE+++ + + L AQ+S
Sbjct: 1020 EDKVNTLTKAKIKLEQQVDDLEGSL----EQEKKLRMDLERAKRK---LEGDLKLAQESI 1072
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ + L+ + ++ E + L +++++ + L K E+ ++ +E+E+E
Sbjct: 1073 MDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAER 1132
Query: 181 DRVKSGDAKISELEEELKVVGNSLK 205
+ + S+L EL+ + L+
Sbjct: 1133 ASRAKAEKQRSDLSRELEEISERLE 1157
Score = 43.2 bits (97), Expect = 0.001
Identities = 30/184 (16%), Positives = 86/184 (46%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K+ ++ ++Q ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 1734 KKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1793
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LE + +++R + L++
Sbjct: 1794 QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRV 1853
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + + ++D ++ + +VKS + E EE+ + L+ E+A
Sbjct: 1854 KELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAE 1913
Query: 216 QRVE 219
+R +
Sbjct: 1914 ERAD 1917
Score = 40.3 bits (90), Expect = 0.007
Identities = 52/222 (23%), Positives = 100/222 (45%), Gaps = 29/222 (13%)
Query: 21 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILNKNKLE---QAN----KD 70
K+ E++ +K+ +E+ + + K ++EE L+ KN L+ QA D
Sbjct: 847 KSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906
Query: 71 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
EE+ QL T+ ++ A K++++ E E EE + K + + E + L
Sbjct: 907 AEERCDQLIKTKIQLEA---KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 963
Query: 131 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR----KLAFVE------DELEVAE 180
E + E+ N++K L E+ G + +++ K A E D+L+ E
Sbjct: 964 ELTLAKVEKEKHATENKVKN---LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020
Query: 181 DRVKSGDAKISELEEELKVVGNSL---KSLEVSEEKANQRVE 219
D+V + +LE+++ + SL K L + E+A +++E
Sbjct: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLE 1062
Score = 39.5 bits (88), Expect = 0.013
Identities = 49/256 (19%), Positives = 98/256 (38%), Gaps = 10/256 (3%)
Query: 12 KLEKDNAMDKADTCEQQA--RDANLRAEKVNEEVRELQKKLAQVEEDL---ILNKN-KLE 65
+LEK + + CE QA +A E ++ +Q +L QV+ ++ I K+ +++
Sbjct: 1531 ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEID 1590
Query: 66 QANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
Q ++ + E + +AE+ + N R +++E DL + E + A + EA ++
Sbjct: 1591 QLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYR 1650
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
+ K + + L QL A + +E+ L E ++AE
Sbjct: 1651 NTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQ 1710
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXX 241
+ ++ L + + N+ K LE + +E+
Sbjct: 1711 ELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAM 1770
Query: 242 XXKTVKKLQKEVDRLE 257
+ +KK Q LE
Sbjct: 1771 MAEELKKEQDTSAHLE 1786
>AK097432-1|BAC05050.1| 466|Homo sapiens protein ( Homo sapiens
cDNA FLJ40113 fis, clone TESTI2008621. ).
Length = 466
Score = 62.5 bits (145), Expect = 2e-09
Identities = 49/215 (22%), Positives = 108/215 (50%), Gaps = 5/215 (2%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTC-EQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
++++ +++QA ++E + + + E++ R+ R + E +RE +++L + EE L
Sbjct: 173 LESVGRQLQA-EVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLHEQEERLCE 231
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
+ +L + + L E E++L E + ++ + EE L + EER +++L E ++
Sbjct: 232 QEERLCEQEERLREHEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLCEQEER 291
Query: 120 -ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
++ R+C+ E R ++ EER+ + +L+E + + + E +L E+ L
Sbjct: 292 LCEQEERLCEQ-EERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLRE 350
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E+R+ + K+ E L+ V L+ EE+
Sbjct: 351 QEERLCEQE-KLPGQERLLEEVEKLLEQERRQEEQ 384
Score = 60.5 bits (140), Expect = 7e-09
Identities = 42/178 (23%), Positives = 86/178 (48%), Gaps = 5/178 (2%)
Query: 26 EQQARDANLRAEKVNEEV-----RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 80
E ++ L+AE N ++ R +++L + EE L + +L + + L E+E++L
Sbjct: 172 ELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLHEQEERLCE 231
Query: 81 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 140
E + ++++ EE L + EER +++L E ++ E + E R + EER
Sbjct: 232 QEERLCEQEERLREHEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLCEQEER 291
Query: 141 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 198
+ + +L E + + + E +L E+ L E+R++ + ++ E EE L+
Sbjct: 292 LCEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLR 349
Score = 59.7 bits (138), Expect = 1e-08
Identities = 46/218 (21%), Positives = 107/218 (49%), Gaps = 3/218 (1%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++K+++++ + ++ R R + E +RE +++L + EE L + +
Sbjct: 169 LRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLHEQEER 228
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS-ADE 122
L + + L E+E++L E + ++++ EE L + EER +++L E ++ ++
Sbjct: 229 LCEQEERLCEQEERLREHEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLCEQ 288
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
R+C+ E R + EER+ + +L E + + + E +L E+ L E+R
Sbjct: 289 EERLCEQ-EERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEER 347
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
++ + ++ E +E+L L+ +E E+ ++ E+
Sbjct: 348 LREQEERLCE-QEKLPGQERLLEEVEKLLEQERRQEEQ 384
Score = 57.2 bits (132), Expect = 6e-08
Identities = 38/165 (23%), Positives = 80/165 (48%), Gaps = 2/165 (1%)
Query: 35 RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 94
+ E++ +E L+K+L V L + + +E++L E + ++++
Sbjct: 158 KVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLRE 217
Query: 95 IEEDLEKSEERSGTAQQKLLEAQQSADENN-RMCKVLENRAQQDEERMDQLTNQLKEARL 153
EE L + EER +++L E ++ E+ R+C+ E R ++ EER+ + +L E
Sbjct: 218 QEERLHEQEERLCEQEERLCEQEERLREHEERLCEQ-EERLREHEERLCEQEERLCEQEE 276
Query: 154 LAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 198
+ + + E +L E+ L E+R++ + ++ E EE L+
Sbjct: 277 RLREQEERLCEQEERLCEQEERLCEQEERLREQEERLCEQEERLR 321
Score = 48.0 bits (109), Expect = 4e-05
Identities = 38/161 (23%), Positives = 74/161 (45%), Gaps = 2/161 (1%)
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+++ K+LE +QL A L+ ++ EE L + EER +++L E ++
Sbjct: 163 QDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERL 222
Query: 121 -DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
++ R+C+ E R + EER+ + +L E + + + E +L E+ L
Sbjct: 223 HEQEERLCE-QEERLCEQEERLREHEERLCEQEERLREHEERLCEQEERLCEQEERLREQ 281
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
E+R+ + ++ E EE L L+ E + +R+ E
Sbjct: 282 EERLCEQEERLCEQEERLCEQEERLREQEERLCEQEERLRE 322
Score = 46.8 bits (106), Expect = 9e-05
Identities = 45/192 (23%), Positives = 89/192 (46%), Gaps = 9/192 (4%)
Query: 25 CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAE 84
CEQ+ R LR + E + E +++L + EE L + +L + + L E+E++L E
Sbjct: 251 CEQEER---LREHE--ERLCEQEERLCEQEERLREQEERLCEQEERLCEQEERLCEQEER 305
Query: 85 VAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQL 144
+ ++ + EE L + EER +++L E ++ E + E R ++E++
Sbjct: 306 LREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERL-CEQEKLPGQ 364
Query: 145 TNQLKEARLLAEDADGKSDE---VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 201
L+E L E + ++ + R+ E E + ++R + ++ E E L+ V
Sbjct: 365 ERLLEEVEKLLEQERRQEEQERLLERERLLEEVEKLLEQERRQEEQERLLERERLLEEVE 424
Query: 202 NSLKSLEVSEEK 213
L+ EE+
Sbjct: 425 KLLEQERRQEEQ 436
Score = 44.4 bits (100), Expect = 5e-04
Identities = 35/173 (20%), Positives = 78/173 (45%), Gaps = 2/173 (1%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQ-VEEDLILNKNKLEQANKDLEEKEKQLTATEAE 84
E++ + +L +K+ + +L+ + A+ + + +K+EQ + K+L + +
Sbjct: 121 EEKKHEIHL-VQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179
Query: 85 VAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQL 144
+ A Q + + EER +++L E ++ E E R + EER+ +
Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLHEQEERLCEQEERLCEQ 239
Query: 145 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 197
+L+E + + + E +L E+ L E+R++ + ++ E EE L
Sbjct: 240 EERLREHEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLCEQEERL 292
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/118 (27%), Positives = 62/118 (52%), Gaps = 9/118 (7%)
Query: 25 CEQQARDANLRAEKVNEEVREL--QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATE 82
CEQ+ E++ EEV +L Q++ + +E L+ + LE+ K LE++ +Q +
Sbjct: 356 CEQEKLPGQ---ERLLEEVEKLLEQERRQEEQERLLERERLLEEVEKLLEQERRQ--EEQ 410
Query: 83 AEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 140
+ R ++++E+ LE +ER Q++LLE ++ DE + +E +Q+ R
Sbjct: 411 ERLLERERLLEEVEKLLE--QERRQEEQERLLERERLLDEVEELLDEVEELLEQERLR 466
>AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa
protein.
Length = 1941
Score = 62.5 bits (145), Expect = 2e-09
Identities = 50/213 (23%), Positives = 110/213 (51%), Gaps = 13/213 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKK++ M+ E ++ + +A E++A+ A A + EE+++ Q A +E +
Sbjct: 1733 KKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 1789
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E ++E ++R+ A + L +
Sbjct: 1790 KN-MEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRK 1848
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
++ E + + ++ +D+L ++K + AE+A+ +S+ K ++ E
Sbjct: 1849 HERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHE 1908
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
LE AE+R ++++++L + + V + S E
Sbjct: 1909 LEEAEERADIAESQVNKLRVKSREVHTKVISEE 1941
Score = 58.4 bits (135), Expect = 3e-08
Identities = 50/226 (22%), Positives = 110/226 (48%), Gaps = 10/226 (4%)
Query: 4 IKKKMQA---MKLEKDNAMDKAD-TCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDL 57
IK K+Q +K + A D+ + E A+ L E ++ +++ +L+ LA+VE++
Sbjct: 915 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 974
Query: 58 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
+NK++ +++ ++ + E AL QQ +DL+ E++ T + ++ +
Sbjct: 975 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLE 1034
Query: 118 QSADENNRMCKVLENRAQQDEERMD-QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
Q D+ + E + + D ER +L LK A+ D + + ++ KL E E+
Sbjct: 1035 QQVDDLEGSLE-QEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEI 1093
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSL--EVSEEKANQRVEE 220
+ +++ A +L++++K + ++ L E+ E+A++ E
Sbjct: 1094 SNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAE 1139
Score = 50.4 bits (115), Expect = 7e-06
Identities = 51/226 (22%), Positives = 109/226 (48%), Gaps = 12/226 (5%)
Query: 1 MDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
++ K+K++ +KL +++ MD + E+Q D L+ ++ E+ LQ K+ + I
Sbjct: 1054 LERAKRKLEGDLKLAQESIMDIEN--EKQQLDEKLKKKEF--EISNLQSKIEDEQALGIQ 1109
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER---SGTAQQKLLEA 116
+ K+++ +EE E+++ A A A ++ + +LE+ ER +G A +E
Sbjct: 1110 LQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEM 1169
Query: 117 QQSAD-ENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVED 174
+ + E +M + LE Q E L + ++ L E D V +KL +
Sbjct: 1170 NKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQID-NLQRVKQKLEKEKS 1228
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
E+++ D + S +S+ + L+ + +L+ ++SE K+ + ++
Sbjct: 1229 EMKMEIDDLASNVETVSKAKGNLEKMCRTLED-QLSELKSKEEEQQ 1273
Score = 49.2 bits (112), Expect = 2e-05
Identities = 47/209 (22%), Positives = 99/209 (47%), Gaps = 15/209 (7%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+Q+ D + + + + EL+K QVE++ + LE+A LE +E ++ + E+
Sbjct: 1512 QQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLEL 1571
Query: 86 ----AALNRKVQQIEED---LEKSEERSGTAQQKLLEAQ-QSADENNRMCKVLENRAQQD 137
+ ++RK+ + +E+ L+++ R + Q L+A+ +S ++ R+ K +E +
Sbjct: 1572 NQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEM 1631
Query: 138 EERMDQLTNQLKEA-------RLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 190
E +++ EA + + +D D+ R ++++L + E R A+I
Sbjct: 1632 EIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEI 1691
Query: 191 SELEEELKVVGNSLKSLEVSEEKANQRVE 219
EL L+ S K E A++RV+
Sbjct: 1692 EELRATLEQTERSRKIAEQELLDASERVQ 1720
Score = 47.2 bits (107), Expect = 7e-05
Identities = 30/165 (18%), Positives = 79/165 (47%)
Query: 49 KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 108
K A+ E+++ K + ++ +L + E + E ++ L ++ ++ ++ E
Sbjct: 847 KSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906
Query: 109 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
A+++ + ++ + K + RA+ +EE +LT + ++ + D++
Sbjct: 907 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 966
Query: 169 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
LA VE E E++VK+ +++ L+E + + K+L+ + ++
Sbjct: 967 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQ 1011
Score = 46.8 bits (106), Expect = 9e-05
Identities = 68/291 (23%), Positives = 123/291 (42%), Gaps = 35/291 (12%)
Query: 12 KLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK-- 69
KLEK+ + K + D E V++ L+K +E+ L K+K E+ +
Sbjct: 1222 KLEKEKSEMK-----MEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLI 1276
Query: 70 -DLE-----------EKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQQKL 113
DL E +QL EA V+ L+R QQIEE L++ E A+ L
Sbjct: 1277 NDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE-LKRQLEEEIKAKNAL 1335
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEV 165
A QS+ + C +L + ++++E +L L +A +A+ DA +++E+
Sbjct: 1336 AHALQSSRHD---CDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEEL 1392
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXX 225
+ L+ AE+ V++ +AK + LE+ + + N ++ L + E+ N
Sbjct: 1393 EEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQ 1452
Query: 226 XXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
++ QKE L EL K+ Y+ D++++
Sbjct: 1453 RNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLET 1503
Score = 45.6 bits (103), Expect = 2e-04
Identities = 37/205 (18%), Positives = 94/205 (45%), Gaps = 7/205 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++ + ++ EK +K ++ + K+ +E + LQ+ Q +DL
Sbjct: 960 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAE 1019
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
++K+ K + E+Q+ E + + +++ DLE+++ + + L AQ+S
Sbjct: 1020 EDKVNTLTKAKIKLEQQVDDLEGSL----EQEKKLRMDLERAKRK---LEGDLKLAQESI 1072
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ + L+ + ++ E + L +++++ + L K E+ ++ +E+E+E
Sbjct: 1073 MDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAER 1132
Query: 181 DRVKSGDAKISELEEELKVVGNSLK 205
+ + S+L EL+ + L+
Sbjct: 1133 ASRAKAEKQRSDLSRELEEISERLE 1157
Score = 43.2 bits (97), Expect = 0.001
Identities = 30/184 (16%), Positives = 86/184 (46%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K+ ++ ++Q ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 1734 KKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1793
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LE + +++R + L++
Sbjct: 1794 QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRV 1853
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + + ++D ++ + +VKS + E EE+ + L+ E+A
Sbjct: 1854 KELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAE 1913
Query: 216 QRVE 219
+R +
Sbjct: 1914 ERAD 1917
Score = 40.3 bits (90), Expect = 0.007
Identities = 52/222 (23%), Positives = 100/222 (45%), Gaps = 29/222 (13%)
Query: 21 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILNKNKLE---QAN----KD 70
K+ E++ +K+ +E+ + + K ++EE L+ KN L+ QA D
Sbjct: 847 KSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906
Query: 71 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
EE+ QL T+ ++ A K++++ E E EE + K + + E + L
Sbjct: 907 AEERCDQLIKTKIQLEA---KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 963
Query: 131 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR----KLAFVE------DELEVAE 180
E + E+ N++K L E+ G + +++ K A E D+L+ E
Sbjct: 964 ELTLAKVEKEKHATENKVKN---LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020
Query: 181 DRVKSGDAKISELEEELKVVGNSL---KSLEVSEEKANQRVE 219
D+V + +LE+++ + SL K L + E+A +++E
Sbjct: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLE 1062
Score = 39.5 bits (88), Expect = 0.013
Identities = 49/256 (19%), Positives = 98/256 (38%), Gaps = 10/256 (3%)
Query: 12 KLEKDNAMDKADTCEQQA--RDANLRAEKVNEEVRELQKKLAQVEEDL---ILNKN-KLE 65
+LEK + + CE QA +A E ++ +Q +L QV+ ++ I K+ +++
Sbjct: 1531 ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEID 1590
Query: 66 QANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
Q ++ + E + +AE+ + N R +++E DL + E + A + EA ++
Sbjct: 1591 QLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYR 1650
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
+ K + + L QL A + +E+ L E ++AE
Sbjct: 1651 NTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQ 1710
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXX 241
+ ++ L + + N+ K LE + +E+
Sbjct: 1711 ELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAM 1770
Query: 242 XXKTVKKLQKEVDRLE 257
+ +KK Q LE
Sbjct: 1771 MAEELKKEQDTSAHLE 1786
>X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy
chain protein.
Length = 1934
Score = 62.1 bits (144), Expect = 2e-09
Identities = 47/206 (22%), Positives = 108/206 (52%), Gaps = 13/206 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKKM A ++ E + A+ + E++A+ A A + EE+++ Q A +E +
Sbjct: 1726 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 1782
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E +LE ++R+ + + + +
Sbjct: 1783 KN-MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRK 1841
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
+++ E + + ++ +D+L ++K + AE+A+ +++ K V+ E
Sbjct: 1842 SERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 1901
Query: 176 LEVAEDRVKSGDAKISELEEELKVVG 201
L+ AE+R ++++++L + + +G
Sbjct: 1902 LDEAEERADIAESQVNKLRAKSRDIG 1927
Score = 59.3 bits (137), Expect = 2e-08
Identities = 48/220 (21%), Positives = 103/220 (46%), Gaps = 7/220 (3%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
K K +LE + M+ T ++ R+ ++ ++ +L+ LA+VE++ +NK+
Sbjct: 918 KVKEMNERLEDEEEMNAELTAKK--RNVEDECSELKRDIDDLELTLAKVEKEKHATENKV 975
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
+ +++ ++ + E AL QQ +DL+ E++ T + ++ +Q D+
Sbjct: 976 KNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLE 1035
Query: 125 RMCKVLENRAQQDEERMD-QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
+ E + + D ER +L LK + D + ++ +L + EL R+
Sbjct: 1036 GSLE-QEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 1094
Query: 184 KSGDAKISELEEELKVVGNSLKSLE---VSEEKANQRVEE 220
+ A S+L+++LK + ++ LE +E A +VE+
Sbjct: 1095 EDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEK 1134
Score = 57.2 bits (132), Expect = 6e-08
Identities = 67/295 (22%), Positives = 126/295 (42%), Gaps = 26/295 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEK----VNEEVRELQKKLAQVE-- 54
+ +K+K++ K E +D + +Q A EK + +++ E + K + +
Sbjct: 1210 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRS 1269
Query: 55 -EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTA 109
DL + KL+ N +L +QL EA ++ L R QQ+ EDL++ E A
Sbjct: 1270 VNDLTSQRAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKA 1325
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGK 161
+ L A QSA + C +L + +++ E +L L +A +A+ DA +
Sbjct: 1326 KNALAHALQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQR 1382
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
++E+ + L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1383 TEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL 1442
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
++ QKE L EL K+ Y+ + +++
Sbjct: 1443 DKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1497
Score = 54.8 bits (126), Expect = 3e-07
Identities = 68/279 (24%), Positives = 129/279 (46%), Gaps = 25/279 (8%)
Query: 5 KKKMQAMKLE---KDNAMDKADTCEQQARD--ANLRAEK--VNEEVRELQKKLAQVEE-- 55
+K+M +MK E A++K++ ++ + +L EK + +V+ Q LA EE
Sbjct: 846 EKEMASMKEEFTALKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERC 905
Query: 56 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
LI NK +LE K++ E+ + AE+ A R V+ +L++ + K +
Sbjct: 906 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRNVEDECSELKRDIDDLELTLAK-V 964
Query: 115 EAQQSADENNRMCKVLENRAQQDE--ERMDQLTNQLKEARLLA-EDADGKSDEVSR---- 167
E ++ A E N++ + E A DE ++ + L+EA A +D + D+V+
Sbjct: 965 EKEKHATE-NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKA 1023
Query: 168 --KLAFVEDELEVAEDRVKSGDAKIS----ELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
KL D+LE + ++ K + +LE +LK+ S+ LE +++ ++R+++
Sbjct: 1024 KVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKK 1083
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
K +K+LQ ++ LE+EL
Sbjct: 1084 DFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1122
Score = 54.4 bits (125), Expect = 4e-07
Identities = 63/282 (22%), Positives = 125/282 (44%), Gaps = 32/282 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 59
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1582
Query: 60 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 115
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1583 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 116 AQQSADENNRMCK----VLEN--RAQQD-------EERMDQLTNQLKEARLLAED----- 157
AQ+ + K L++ RA D ER + L +L+E R + E
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLQAELEELRAVVEQTERSR 1698
Query: 158 --ADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
AD + E S ++ + + ++ K DA +S+L+ E++ ++ E +KA
Sbjct: 1699 KLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAI 1758
Query: 216 QRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLE 257
+T+K LQ +D E
Sbjct: 1759 TDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 1800
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 146 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 193
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 194 EEELKVVGNSLKSLEVSEEKANQ 216
+ E + +L+ + E N+
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLNE 1624
Score = 52.4 bits (120), Expect = 2e-06
Identities = 51/211 (24%), Positives = 101/211 (47%), Gaps = 18/211 (8%)
Query: 5 KKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI-LNK- 61
+++M A + +K N D+ ++ D L KV +E + K+ + E++ L++
Sbjct: 929 EEEMNAELTAKKRNVEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEI 988
Query: 62 -NKLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQQKL 113
KL + K L+E +Q L A E +V L + K++Q +DLE S E+ + L
Sbjct: 989 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 1048
Query: 114 LEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
A++ + + ++ + LEN QQ +ER+ + +L ED ++ +KL
Sbjct: 1049 ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKL 1108
Query: 170 AFVEDELEVAEDRV---KSGDAKISELEEEL 197
++ +E E+ + ++ AK+ +L +L
Sbjct: 1109 KELQARIEELEEELEAERTARAKVEKLRSDL 1139
Score = 52.0 bits (119), Expect = 2e-06
Identities = 38/170 (22%), Positives = 82/170 (48%), Gaps = 7/170 (4%)
Query: 45 ELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 104
E +K++A ++E+ K LE++ +E E+++ + E L +VQ +++L +EE
Sbjct: 844 EREKEMASMKEEFTALKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 903
Query: 105 RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 164
R + ++ + E N R + +EE +LT + + + D+
Sbjct: 904 RCDQLIKNKIQLEAKVKEMNE-------RLEDEEEMNAELTAKKRNVEDECSELKRDIDD 956
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
+ LA VE E E++VK+ +++ L+E + + K+L+ + ++A
Sbjct: 957 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 1006
Score = 52.0 bits (119), Expect = 2e-06
Identities = 44/260 (16%), Positives = 101/260 (38%), Gaps = 10/260 (3%)
Query: 11 MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ E+DN D + C+Q + ++ N R E E EL K VE++
Sbjct: 891 VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRNVEDECSEL 950
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K ++ L + EK+ ATE +V L ++ ++E + K + Q+ +A
Sbjct: 951 KRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDL 1010
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
L + E+++D L L++ + + D + ++ L ++ + E
Sbjct: 1011 QAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLE 1070
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+ + D ++ + + EL + ++ + + ++++E
Sbjct: 1071 NDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARA 1130
Query: 241 XXXKTVKKLQKEVDRLEDEL 260
K L +E++ + + L
Sbjct: 1131 KVEKLRSDLSRELEEISERL 1150
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/201 (22%), Positives = 87/201 (43%), Gaps = 4/201 (1%)
Query: 24 TCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 83
T QQ D + E+ + L L D L + + E+ + E ++ L+ +
Sbjct: 1307 TYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANS 1366
Query: 84 EVAALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 142
EVA K + + E+ EE Q+L EA+++ + N C LE + + ++
Sbjct: 1367 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE 1426
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 202
L ++ + A D K + LA + + E ++ ++S + L EL + N
Sbjct: 1427 DLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKN 1486
Query: 203 SL-KSLEVSE--EKANQRVEE 220
+ +SLE E ++ N+ ++E
Sbjct: 1487 AYEESLEHLETFKRENKNLQE 1507
Score = 46.4 bits (105), Expect = 1e-04
Identities = 33/153 (21%), Positives = 72/153 (47%), Gaps = 3/153 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1004 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 1061 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 1120
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+L+ R + ++SR+L + + LE A
Sbjct: 1121 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 1153
Score = 45.6 bits (103), Expect = 2e-04
Identities = 56/293 (19%), Positives = 127/293 (43%), Gaps = 20/293 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++ + ++ EK +K ++ + K+ +E + LQ+ Q +DL
Sbjct: 954 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE 1013
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
++K+ K + E+Q+ E + + +++ DLE++ +R KL +
Sbjct: 1014 EDKVNTLTKAKVKLEQQVDDLEGSL----EQEKKVRMDLERA-KRKLEGDLKLTQESIMD 1068
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
EN++ + L+ R ++ + ++ L ++++ + L K E+ ++ +E+ELE AE
Sbjct: 1069 LENDK--QQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELE-AE 1125
Query: 181 DRVKSGDAKI-SELEEELKVVGNSLK----SLEVSEEKANQRVEEFXXXXXXXXXXXXXX 235
++ K+ S+L EL+ + L+ + E +R EF
Sbjct: 1126 RTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKREAEFQKMRRDLEEATLQH 1185
Query: 236 XXXXXXXXK----TVKKLQKEVD---RLEDELGINKDRYKSLADEMDSTFAEL 281
K +V +L +++D R++ +L K +K D++ S ++
Sbjct: 1186 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQI 1238
Score = 45.6 bits (103), Expect = 2e-04
Identities = 57/273 (20%), Positives = 115/273 (42%), Gaps = 19/273 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDA---NLRAE-KVNEEVRELQKKLAQVEEDLIL 59
IK +++ EKD M++A + D+ +L AE + E ++KK+ E DL
Sbjct: 1568 IKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKM---EGDLNE 1624
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ---QIEEDLEKS---EERSGTAQQKL 113
+ +L AN+ E +KQ+ + ++ + ++ + +DL+++ ER Q +L
Sbjct: 1625 MEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLQAEL 1684
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
E + ++ R K+ + + ER+ L +Q + D ++ ++
Sbjct: 1685 EELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAV 1744
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXX 233
E AE++ K + + EELK ++ LE ++ Q +++
Sbjct: 1745 QECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDL------QHRLDE 1798
Query: 234 XXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
K ++KL+ V LE+EL + R
Sbjct: 1799 AEQIALKGGKKQLQKLEARVRELENELEAEQKR 1831
Score = 44.0 bits (99), Expect = 6e-04
Identities = 29/184 (15%), Positives = 90/184 (48%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K++ ++ +LQ ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 1727 KKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1786
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LEN + +++R + ++++
Sbjct: 1787 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRI 1846
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + L ++D ++ + +VK+ + E EE+ + + ++ ++A
Sbjct: 1847 KELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAE 1906
Query: 216 QRVE 219
+R +
Sbjct: 1907 ERAD 1910
Score = 41.5 bits (93), Expect = 0.003
Identities = 49/227 (21%), Positives = 102/227 (44%), Gaps = 19/227 (8%)
Query: 12 KLEKDNAMDKADTCEQQAR-----DANLRAEKVNEEVRELQKKLAQVEEDL--------I 58
K E + KA++ Q R DA R E++ E ++L ++L + EE +
Sbjct: 1354 KAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSS 1413
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
L K K + ++E+ + + A AAL++K + ++ L + +++ +Q +L +Q+
Sbjct: 1414 LEKTK-HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQK 1472
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD---GKSDEVSRKLAFVEDE 175
A + L+N ++ E ++ + K + D G S + +L V +
Sbjct: 1473 EARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQ 1532
Query: 176 LEVAEDRVKSG--DAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
LE + ++S +A+ S EE K++ L+ ++ E + E+
Sbjct: 1533 LEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEK 1579
Score = 39.9 bits (89), Expect = 0.010
Identities = 35/166 (21%), Positives = 72/166 (43%), Gaps = 19/166 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTC-----EQQARDANLRAEKVNEEVRELQKKLAQVEE 55
++ +KK M+ + + +D+A+ ++Q + R ++ E+ QK+ A+ +
Sbjct: 1778 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVK 1837
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ ++ ++++ EE K L + V L KV+ + E++EE++ T K +
Sbjct: 1838 GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRK 1897
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
Q DE EER D +Q+ + R + D K
Sbjct: 1898 VQHELDEA--------------EERADIAESQVNKLRAKSRDIGTK 1929
Score = 31.5 bits (68), Expect = 3.5
Identities = 38/179 (21%), Positives = 78/179 (43%), Gaps = 10/179 (5%)
Query: 19 MDKADTCEQQARDANLRAEKVNEEVRE--LQKKLAQVEEDLILNKNKLEQANKDLEEKEK 76
M+K E Q +L + E L+KK A +L + L++ + LE+++
Sbjct: 1163 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1222
Query: 77 QLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ 136
+ + E+ + ++QI + E+ T + ++ E + A+E R L ++ +
Sbjct: 1223 EF---KLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAK 1279
Query: 137 DEERMDQLTNQLKEAR-LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 194
+ +L+ QL E L+++ GK + +ED E+ VK+ +A L+
Sbjct: 1280 LQTENGELSRQLDEKEALISQLTRGKLTYTQQ----LEDLKRQLEEEVKAKNALAHALQ 1334
>X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain (1151
AA) protein.
Length = 1151
Score = 62.1 bits (144), Expect = 2e-09
Identities = 47/206 (22%), Positives = 108/206 (52%), Gaps = 13/206 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKKM A ++ E + A+ + E++A+ A A + EE+++ Q A +E +
Sbjct: 943 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 999
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E +LE ++R+ + + + +
Sbjct: 1000 KN-MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRK 1058
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
+++ E + + ++ +D+L ++K + AE+A+ +++ K V+ E
Sbjct: 1059 SERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 1118
Query: 176 LEVAEDRVKSGDAKISELEEELKVVG 201
L+ AE+R ++++++L + + +G
Sbjct: 1119 LDEAEERADIAESQVNKLRAKSRDIG 1144
Score = 57.2 bits (132), Expect = 6e-08
Identities = 67/295 (22%), Positives = 126/295 (42%), Gaps = 26/295 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEK----VNEEVRELQKKLAQVE-- 54
+ +K+K++ K E +D + +Q A EK + +++ E + K + +
Sbjct: 426 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRS 485
Query: 55 -EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTA 109
DL + KL+ N +L +QL EA ++ L R QQ+ EDL++ E A
Sbjct: 486 VNDLTSQRAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKA 541
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGK 161
+ L A QSA + C +L + +++ E +L L +A +A+ DA +
Sbjct: 542 KNALAHALQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQR 598
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
++E+ + L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 599 TEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL 658
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
++ QKE L EL K+ Y+ + +++
Sbjct: 659 DKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 713
Score = 55.2 bits (127), Expect = 2e-07
Identities = 68/279 (24%), Positives = 129/279 (46%), Gaps = 25/279 (8%)
Query: 5 KKKMQAMKLE---KDNAMDKADTCEQQARD--ANLRAEK--VNEEVRELQKKLAQVEE-- 55
+K+M +MK E A++K++ ++ + +L EK + +V+ Q LA EE
Sbjct: 62 EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERC 121
Query: 56 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
LI NK +LE K++ E+ + AE+ A RK++ +L++ + K +
Sbjct: 122 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAK-V 180
Query: 115 EAQQSADENNRMCKVLENRAQQDE--ERMDQLTNQLKEARLLA-EDADGKSDEVSR---- 167
E ++ A E N++ + E A DE ++ + L+EA A +D + D+V+
Sbjct: 181 EKEKHATE-NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKA 239
Query: 168 --KLAFVEDELEVAEDRVKSGDAKIS----ELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
KL D+LE + ++ K + +LE +LK+ S+ LE +++ +R+++
Sbjct: 240 KVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLEERLKKK 299
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
K +K+LQ ++ LE+EL
Sbjct: 300 DFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 338
Score = 54.8 bits (126), Expect = 3e-07
Identities = 56/230 (24%), Positives = 115/230 (50%), Gaps = 23/230 (10%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 59
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 742 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 798
Query: 60 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 115
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 799 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 854
Query: 116 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 166
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 855 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 914
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
RKLA ++EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 915 RKLA--DEELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 962
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 638 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 697
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 698 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 757
Query: 146 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 193
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 758 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 817
Query: 194 EEELKVVGNSLKSLEVSEEKANQ 216
+ E + +L+ + E N+
Sbjct: 818 DAETRSRNEALRVKKKMEGDLNE 840
Score = 52.0 bits (119), Expect = 2e-06
Identities = 69/310 (22%), Positives = 135/310 (43%), Gaps = 33/310 (10%)
Query: 5 KKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI-LNK- 61
+++M A + +K D+ ++ D L KV +E + K+ + E++ L++
Sbjct: 145 EEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEI 204
Query: 62 -NKLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQQKL 113
KL + K L+E +Q L A E +V L + K++Q +DLE S E+ + L
Sbjct: 205 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 264
Query: 114 LEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
A++ + + ++ + LEN QQ EER+ + +L ED ++ +KL
Sbjct: 265 ERAKRKLEGDLKLTQESIMDLENDKQQLEERLKKKDFELNALNARIEDEQALGSQLQKKL 324
Query: 170 AFVEDELEVAEDRV---KSGDAKI----SELEEELKVVGNSLK----SLEVSEEKANQRV 218
++ +E E+ + ++ AK+ S+L EL+ + L+ + V E +R
Sbjct: 325 KELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKRE 384
Query: 219 EEFXXXXXXXXXXXXXXXXXXXXXXK----TVKKLQKEVD---RLEDELGINKDRYKSLA 271
EF K +V +L +++D R++ +L K +K
Sbjct: 385 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 444
Query: 272 DEMDSTFAEL 281
D++ S ++
Sbjct: 445 DDVTSNMEQI 454
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/201 (22%), Positives = 87/201 (43%), Gaps = 4/201 (1%)
Query: 24 TCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 83
T QQ D + E+ + L L D L + + E+ + E ++ L+ +
Sbjct: 523 TYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANS 582
Query: 84 EVAALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 142
EVA K + + E+ EE Q+L EA+++ + N C LE + + ++
Sbjct: 583 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE 642
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 202
L ++ + A D K + LA + + E ++ ++S + L EL + N
Sbjct: 643 DLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKN 702
Query: 203 SL-KSLEVSE--EKANQRVEE 220
+ +SLE E ++ N+ ++E
Sbjct: 703 AYEESLEHLETFKRENKNLQE 723
Score = 51.6 bits (118), Expect = 3e-06
Identities = 38/170 (22%), Positives = 83/170 (48%), Gaps = 7/170 (4%)
Query: 45 ELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 104
E +K++A ++E+ K LE++ +E E+++ + E L +VQ +++L +EE
Sbjct: 60 EREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 119
Query: 105 RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 164
R + ++ + E N R + +EE +LT + ++ + D+
Sbjct: 120 RCDQLIKNKIQLEAKVKEMNE-------RLEDEEEMNAELTAKKRKLEDECSELKRDIDD 172
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
+ LA VE E E++VK+ +++ L+E + + K+L+ + ++A
Sbjct: 173 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 222
Score = 48.4 bits (110), Expect = 3e-05
Identities = 51/264 (19%), Positives = 107/264 (40%), Gaps = 8/264 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRE-LQKKLAQVEEDLILNKN 62
+ +K + M+ K N + D+ Q + DA R+ V++ ++ L ++E L
Sbjct: 792 LAEKDEEMEQAKRNHLRVVDSL-QTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANR 850
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+A K ++ + L T+ ++ R ++E++ E R+ Q +L E + ++
Sbjct: 851 MAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 910
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
R K+ + + ER+ L +Q + D ++ ++ E AE++
Sbjct: 911 TERSRKLADEELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEK 970
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXX 242
K + + EELK ++ LE ++ Q +++
Sbjct: 971 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDL------QHRLDEAEQIALKGG 1024
Query: 243 XKTVKKLQKEVDRLEDELGINKDR 266
K ++KL+ V LE+EL + R
Sbjct: 1025 KKQLQKLEARVRELENELEAEQKR 1048
Score = 44.0 bits (99), Expect = 6e-04
Identities = 29/184 (15%), Positives = 90/184 (48%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K++ ++ +LQ ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 944 KKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1003
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LEN + +++R + ++++
Sbjct: 1004 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRI 1063
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + L ++D ++ + +VK+ + E EE+ + + ++ ++A
Sbjct: 1064 KELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAE 1123
Query: 216 QRVE 219
+R +
Sbjct: 1124 ERAD 1127
Score = 41.5 bits (93), Expect = 0.003
Identities = 49/227 (21%), Positives = 102/227 (44%), Gaps = 19/227 (8%)
Query: 12 KLEKDNAMDKADTCEQQAR-----DANLRAEKVNEEVRELQKKLAQVEEDL--------I 58
K E + KA++ Q R DA R E++ E ++L ++L + EE +
Sbjct: 570 KAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSS 629
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
L K K + ++E+ + + A AAL++K + ++ L + +++ +Q +L +Q+
Sbjct: 630 LEKTK-HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQK 688
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD---GKSDEVSRKLAFVEDE 175
A + L+N ++ E ++ + K + D G S + +L V +
Sbjct: 689 EARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQ 748
Query: 176 LEVAEDRVKSG--DAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
LE + ++S +A+ S EE K++ L+ ++ E + E+
Sbjct: 749 LEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEK 795
Score = 39.9 bits (89), Expect = 0.010
Identities = 35/166 (21%), Positives = 72/166 (43%), Gaps = 19/166 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTC-----EQQARDANLRAEKVNEEVRELQKKLAQVEE 55
++ +KK M+ + + +D+A+ ++Q + R ++ E+ QK+ A+ +
Sbjct: 995 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVK 1054
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ ++ ++++ EE K L + V L KV+ + E++EE++ T K +
Sbjct: 1055 GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRK 1114
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
Q DE EER D +Q+ + R + D K
Sbjct: 1115 VQHELDEA--------------EERADIAESQVNKLRAKSRDIGTK 1146
Score = 31.5 bits (68), Expect = 3.5
Identities = 38/179 (21%), Positives = 78/179 (43%), Gaps = 10/179 (5%)
Query: 19 MDKADTCEQQARDANLRAEKVNEEVRE--LQKKLAQVEEDLILNKNKLEQANKDLEEKEK 76
M+K E Q +L + E L+KK A +L + L++ + LE+++
Sbjct: 379 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 438
Query: 77 QLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ 136
+ + E+ + ++QI + E+ T + ++ E + A+E R L ++ +
Sbjct: 439 EF---KLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAK 495
Query: 137 DEERMDQLTNQLKEAR-LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 194
+ +L+ QL E L+++ GK + +ED E+ VK+ +A L+
Sbjct: 496 LQTENGELSRQLDEKEALISQLTRGKLTYTQQ----LEDLKRQLEEEVKAKNALAHALQ 550
>X13939-1|CAA32122.1| 328|Homo sapiens laminin B2 protein.
Length = 328
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 6/172 (3%)
Query: 33 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 92
N + NE+ RE Q+ L D KNK +A + +K T+T+AE +V
Sbjct: 114 NQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEV 173
Query: 93 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
++ ++ ++ A+++L Q AD++ M + AQ+ E + N +
Sbjct: 174 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 233
Query: 153 LLAED---ADGKSDEVS-RKLAFVEDELEVAEDRVKSG--DAKISELEEELK 198
+ D G+ D V KL +E L A+D +K D K+S+LE E K
Sbjct: 234 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAK 285
Score = 45.2 bits (102), Expect = 3e-04
Identities = 41/178 (23%), Positives = 72/178 (40%), Gaps = 7/178 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++ M+ +LE N ++K T +Q A RA+ E KK D + N
Sbjct: 29 LREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKK----GRDTLQEAND 84
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ KD + + T AE A RK+ I + + ++ E++ AQQ L A A E
Sbjct: 85 ILNNLKDFDRRVND-NKTAAEEAL--RKIPAINQTITEANEKTREAQQALGSAAADATEA 141
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E A ++ + + D D + + + ++L E EL+ +D
Sbjct: 142 KNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKRKQD 199
Score = 32.3 bits (70), Expect = 2.0
Identities = 41/216 (18%), Positives = 82/216 (37%), Gaps = 13/216 (6%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D + + A K + A K Q+A D + + V + + + +
Sbjct: 55 DQLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAIN 114
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT-----AQQKLLEA 116
+ +AN+ E ++ L + A+ K + E + + +++ T A++ E
Sbjct: 115 QTITEANEKTREAQQALGSAAADATEAKNKAHEAER-IASAVQKNATSTKAEAERTFAEV 173
Query: 117 QQSADENNRMCKVLE------NRAQQDEERMDQLTNQLKEARLLAE-DADGKSDEVSRKL 169
+E N M K L+ R Q D ++ + +A AE +A + V+ L
Sbjct: 174 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 233
Query: 170 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
+ + D LE K++E+E L + +K
Sbjct: 234 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMK 269
Score = 30.3 bits (65), Expect = 8.0
Identities = 26/199 (13%), Positives = 65/199 (32%)
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+N+ + E E+ + + L ++ E +++ E+ T QQ + A
Sbjct: 2 ENEANNIKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARA 61
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
D + + + + + + + N LK+ D ++E RK+ + + A
Sbjct: 62 DAAKALAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAINQTITEAN 121
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
++ + + + N E +
Sbjct: 122 EKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVN 181
Query: 241 XXXKTVKKLQKEVDRLEDE 259
K +++ +KE+ R +D+
Sbjct: 182 NMLKQLQEAEKELKRKQDD 200
>X06976-1|CAA30039.1| 543|Homo sapiens beta myosin heavy chain (
544 AA) protein.
Length = 543
Score = 62.1 bits (144), Expect = 2e-09
Identities = 47/206 (22%), Positives = 108/206 (52%), Gaps = 13/206 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKKM A ++ E + A+ + E++A+ A A + EE+++ Q A +E +
Sbjct: 335 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 391
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E +LE ++R+ + + + +
Sbjct: 392 KN-MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRK 450
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
+++ E + + ++ +D+L ++K + AE+A+ +++ K V+ E
Sbjct: 451 SERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 510
Query: 176 LEVAEDRVKSGDAKISELEEELKVVG 201
L+ AE+R ++++++L + + +G
Sbjct: 511 LDEAEERADIAESQVNKLRAKSRDIG 536
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 30 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 89
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 90 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 149
Query: 146 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 193
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 150 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 209
Query: 194 EEELKVVGNSLKSLEVSEEKANQ 216
+ E + +L+ + E N+
Sbjct: 210 DAETRSRNEALRVKKKMEGDLNE 232
Score = 54.0 bits (124), Expect = 6e-07
Identities = 51/276 (18%), Positives = 120/276 (43%), Gaps = 19/276 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDL-I 58
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E++
Sbjct: 134 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 193
Query: 59 LNKNKLE-----QANKDLEEK------------EKQLTATEAEVAALNRKVQQIEEDLEK 101
+N L Q + D E + E L E +++ NR + ++ ++
Sbjct: 194 AKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS 253
Query: 102 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
+ Q +L +A ++ D+ ++E R + +++L +++ + AD +
Sbjct: 254 LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADRE 313
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
E S ++ + + ++ K DA +S+L+ E++ ++ E +KA
Sbjct: 314 LIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMM 373
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLE 257
+T+K LQ +D E
Sbjct: 374 AEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 409
Score = 48.4 bits (110), Expect = 3e-05
Identities = 41/238 (17%), Positives = 100/238 (42%), Gaps = 7/238 (2%)
Query: 27 QQARDANLRAEKVNEEVRELQK---KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 83
Q+ ++A E VN + L+K +L EDL+++ + A L++K++ A
Sbjct: 3 QRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILA 62
Query: 84 EVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQ 143
E +K ++ + +LE S++ + + +L + + + +E+ + + + +E +
Sbjct: 63 E---WKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISD 119
Query: 144 LTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNS 203
LT QL + + + ++ + ++ LE AE ++ + KI + E +
Sbjct: 120 LTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAE 179
Query: 204 L-KSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
+ + L +E+ Q + KK++ +++ +E +L
Sbjct: 180 IERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQL 237
Score = 48.4 bits (110), Expect = 3e-05
Identities = 51/264 (19%), Positives = 107/264 (40%), Gaps = 8/264 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRE-LQKKLAQVEEDLILNKN 62
+ +K + M+ K N + D+ Q + DA R+ V++ ++ L ++E L
Sbjct: 184 LAEKDEEMEQAKRNHLRVVDSL-QTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANR 242
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+A K ++ + L T+ ++ R ++E++ E R+ Q +L E + ++
Sbjct: 243 MAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 302
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
R K+ + + ER+ L +Q + D ++ ++ E AE++
Sbjct: 303 TERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEK 362
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXX 242
K + + EELK ++ LE ++ Q +++
Sbjct: 363 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDL------QHRLDEAEQIALKGG 416
Query: 243 XKTVKKLQKEVDRLEDELGINKDR 266
K ++KL+ V LE+EL + R
Sbjct: 417 KKQLQKLEARVRELENELEAEQKR 440
Score = 44.0 bits (99), Expect = 6e-04
Identities = 29/184 (15%), Positives = 90/184 (48%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K++ ++ +LQ ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 336 KKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 395
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LEN + +++R + ++++
Sbjct: 396 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRI 455
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + L ++D ++ + +VK+ + E EE+ + + ++ ++A
Sbjct: 456 KELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAE 515
Query: 216 QRVE 219
+R +
Sbjct: 516 ERAD 519
Score = 39.9 bits (89), Expect = 0.010
Identities = 35/166 (21%), Positives = 72/166 (43%), Gaps = 19/166 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTC-----EQQARDANLRAEKVNEEVRELQKKLAQVEE 55
++ +KK M+ + + +D+A+ ++Q + R ++ E+ QK+ A+ +
Sbjct: 387 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVK 446
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ ++ ++++ EE K L + V L KV+ + E++EE++ T K +
Sbjct: 447 GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRK 506
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
Q DE EER D +Q+ + R + D K
Sbjct: 507 VQHELDEA--------------EERADIAESQVNKLRAKSRDIGTK 538
Score = 32.3 bits (70), Expect = 2.0
Identities = 38/188 (20%), Positives = 84/188 (44%), Gaps = 14/188 (7%)
Query: 46 LQKKLAQVEEDL--------ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 97
L ++L + EE + L K K + ++E+ + + A AAL++K + ++
Sbjct: 1 LAQRLQEAEEAVEAVNAKCSSLEKTK-HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDK 59
Query: 98 DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 157
L + +++ +Q +L +Q+ A + L+N ++ E ++ + K + D
Sbjct: 60 ILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISD 119
Query: 158 AD---GKSDEVSRKLAFVEDELEVAEDRVKSG--DAKISELEEELKVVGNSLKSLEVSEE 212
G S + +L V +LE + ++S +A+ S EE K++ L+ ++ E
Sbjct: 120 LTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAE 179
Query: 213 KANQRVEE 220
+ E+
Sbjct: 180 IERKLAEK 187
>X03741-1|CAA27381.1| 635|Homo sapiens protein ( Human cardiac mRNA
for myosin heavy chain light meromyosin region. ).
Length = 635
Score = 62.1 bits (144), Expect = 2e-09
Identities = 47/206 (22%), Positives = 108/206 (52%), Gaps = 13/206 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKKM A ++ E + A+ + E++A+ A A + EE+++ Q A +E +
Sbjct: 427 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 483
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E +LE ++R+ + + + +
Sbjct: 484 KN-MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRK 542
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
+++ E + + ++ +D+L ++K + AE+A+ +++ K V+ E
Sbjct: 543 SERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 602
Query: 176 LEVAEDRVKSGDAKISELEEELKVVG 201
L+ AE+R ++++++L + + +G
Sbjct: 603 LDEAEERADIAESQVNKLRAKSRDIG 628
Score = 55.6 bits (128), Expect = 2e-07
Identities = 40/191 (20%), Positives = 80/191 (41%), Gaps = 2/191 (1%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 122 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 181
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 182 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 241
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
+ L+EA E +GK + +L F + + E+ R + + L+VV +
Sbjct: 242 SALEEAEASLEHEEGKI--LRAQLEFNQIKAEIERKRQEKDEEMEQAKRNHLRVVDSLQT 299
Query: 206 SLEVSEEKANQ 216
SL+ N+
Sbjct: 300 SLDAETRSRNE 310
Score = 51.6 bits (118), Expect = 3e-06
Identities = 42/285 (14%), Positives = 120/285 (42%), Gaps = 1/285 (0%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D+++ + A ++ A+ E + ++ N E QK++ ++ L
Sbjct: 294 VDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDT 353
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L+ A + ++ ++ + E L +++++ +E++E A+Q+L+E +
Sbjct: 354 QIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERV 413
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L N+ ++ + + QL +++EA +A+ K+ + A + +EL+ +
Sbjct: 414 QLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQ 473
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + +E+ +K + + L E ++ + +++++
Sbjct: 474 DTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRN 533
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K ++ + L + ++ L D +D ++ Y
Sbjct: 534 AESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 578
Score = 50.8 bits (116), Expect = 5e-06
Identities = 55/230 (23%), Positives = 112/230 (48%), Gaps = 23/230 (10%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 59
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++K + +E+
Sbjct: 226 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKRQEKDEE--- 282
Query: 60 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 115
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 283 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 338
Query: 116 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 166
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 339 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 398
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
RKLA E EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 399 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 446
Score = 47.6 bits (108), Expect = 5e-05
Identities = 42/261 (16%), Positives = 110/261 (42%), Gaps = 8/261 (3%)
Query: 5 KKKMQAMKLEKDNAMDKADT-CEQQARDANLRAEKVNEEVRELQK---KLAQVEEDLILN 60
+ K + +++ +++A Q+ ++A E VN + L+K +L EDL+++
Sbjct: 72 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 131
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ A L++K++ AE +K ++ + +LE S++ + + +L + + +
Sbjct: 132 VERSNAAAAALDKKQRNFDKILAE---WKQKYEESQSELESSQKEARSLSTELFKLKNAY 188
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+E+ + + + +E + LT QL + + + ++ + ++ LE AE
Sbjct: 189 EESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAE 248
Query: 181 DRVKSGDAKISELEEELKVVGNSL-KSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
++ + KI + E + + + + +E+ Q
Sbjct: 249 ASLEHEEGKILRAQLEFNQIKAEIERKRQEKDEEMEQAKRNHLRVVDSLQTSLDAETRSR 308
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
+ KK++ +++ +E +L
Sbjct: 309 NEALRVKKKMEGDLNEMEIQL 329
Score = 46.0 bits (104), Expect = 2e-04
Identities = 47/208 (22%), Positives = 101/208 (48%), Gaps = 24/208 (11%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+++ D + + + EL+K Q+E + + ++ LE+A LE +E ++ + E
Sbjct: 206 QEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEF 265
Query: 86 ----AALNRKVQQIEEDLEKSEE---RSGTAQQKLLEAQ-QSADENNRMCKVLE------ 131
A + RK Q+ +E++E+++ R + Q L+A+ +S +E R+ K +E
Sbjct: 266 NQIKAEIERKRQEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEM 325
Query: 132 -------NR-AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
NR A + ++++ L + LK+ ++ +DA +D++ +A VE + + +
Sbjct: 326 EIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAEL 385
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSE 211
+ A + + E K+ L +E SE
Sbjct: 386 EELRAVVEQTERSRKLAEQEL--IETSE 411
Score = 45.6 bits (103), Expect = 2e-04
Identities = 42/197 (21%), Positives = 83/197 (42%), Gaps = 4/197 (2%)
Query: 28 QARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAA 87
Q D + E+ + L L D L + + E+ + + L+ +EVA
Sbjct: 11 QLGDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKARLQGDLSKANSEVAQ 70
Query: 88 LNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
K + + E+ EE Q+L EA+++ + N C LE + + ++ L
Sbjct: 71 WRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMV 130
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL-K 205
++ + A D K + LA + + E ++ ++S + L EL + N+ +
Sbjct: 131 DVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 190
Query: 206 SLEVSE--EKANQRVEE 220
SLE E ++ N+ ++E
Sbjct: 191 SLEHLETFKRENKNLQE 207
Score = 44.0 bits (99), Expect = 6e-04
Identities = 29/184 (15%), Positives = 90/184 (48%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K++ ++ +LQ ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 428 KKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 487
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LEN + +++R + ++++
Sbjct: 488 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRI 547
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + L ++D ++ + +VK+ + E EE+ + + ++ ++A
Sbjct: 548 KELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAE 607
Query: 216 QRVE 219
+R +
Sbjct: 608 ERAD 611
Score = 39.9 bits (89), Expect = 0.010
Identities = 35/166 (21%), Positives = 72/166 (43%), Gaps = 19/166 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTC-----EQQARDANLRAEKVNEEVRELQKKLAQVEE 55
++ +KK M+ + + +D+A+ ++Q + R ++ E+ QK+ A+ +
Sbjct: 479 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVK 538
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ ++ ++++ EE K L + V L KV+ + E++EE++ T K +
Sbjct: 539 GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRK 598
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
Q DE EER D +Q+ + R + D K
Sbjct: 599 VQHELDEA--------------EERADIAESQVNKLRAKSRDIGTK 630
>M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 62.1 bits (144), Expect = 2e-09
Identities = 47/206 (22%), Positives = 108/206 (52%), Gaps = 13/206 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKKM A ++ E + A+ + E++A+ A A + EE+++ Q A +E +
Sbjct: 1727 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 1783
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E +LE ++R+ + + + +
Sbjct: 1784 KN-MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRK 1842
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
+++ E + + ++ +D+L ++K + AE+A+ +++ K V+ E
Sbjct: 1843 SERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 1902
Query: 176 LEVAEDRVKSGDAKISELEEELKVVG 201
L+ AE+R ++++++L + + +G
Sbjct: 1903 LDEAEERADIAESQVNKLRAKSRDIG 1928
Score = 57.2 bits (132), Expect = 6e-08
Identities = 67/295 (22%), Positives = 126/295 (42%), Gaps = 26/295 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEK----VNEEVRELQKKLAQVE-- 54
+ +K+K++ K E +D + +Q A EK + +++ E + K + +
Sbjct: 1210 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRS 1269
Query: 55 -EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTA 109
DL + KL+ N +L +QL EA ++ L R QQ+ EDL++ E A
Sbjct: 1270 VNDLTSQRAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKA 1325
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGK 161
+ L A QSA + C +L + +++ E +L L +A +A+ DA +
Sbjct: 1326 KNALAHALQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQR 1382
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
++E+ + L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1383 TEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL 1442
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
++ QKE L EL K+ Y+ + +++
Sbjct: 1443 DKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1497
Score = 55.6 bits (128), Expect = 2e-07
Identities = 68/279 (24%), Positives = 130/279 (46%), Gaps = 25/279 (8%)
Query: 5 KKKMQAMKLE---KDNAMDKADTCEQQARD--ANLRAEK--VNEEVRELQKKLAQVEE-- 55
+K+M +MK E A++K++ ++ + +L EK + +V+ Q LA EE
Sbjct: 846 EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERC 905
Query: 56 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
LI NK +LE K++ E+ + AE+ A RK++ +L++ + K +
Sbjct: 906 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAK-V 964
Query: 115 EAQQSADENNRMCKVLENRAQQDE--ERMDQLTNQLKEARLLA-EDADGKSDEVSR---- 167
E ++ A E N++ + E A DE ++ + L+EA A +D + D+V+
Sbjct: 965 EKEKHATE-NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKA 1023
Query: 168 --KLAFVEDELEVAEDRVKSGDAKIS----ELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
KL D+LE + ++ K + +LE +LK+ S+ LE +++ ++R+++
Sbjct: 1024 KVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKK 1083
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
K +K+LQ ++ LE+EL
Sbjct: 1084 DFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1122
Score = 55.2 bits (127), Expect = 2e-07
Identities = 57/230 (24%), Positives = 114/230 (49%), Gaps = 23/230 (10%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 59
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1582
Query: 60 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 115
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1583 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 116 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 166
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
RKLA E EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 1699 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 1746
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 146 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 193
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 194 EEELKVVGNSLKSLEVSEEKANQ 216
+ E + +L+ + E N+
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLNE 1624
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/201 (22%), Positives = 87/201 (43%), Gaps = 4/201 (1%)
Query: 24 TCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 83
T QQ D + E+ + L L D L + + E+ + E ++ L+ +
Sbjct: 1307 TYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANS 1366
Query: 84 EVAALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 142
EVA K + + E+ EE Q+L EA+++ + N C LE + + ++
Sbjct: 1367 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE 1426
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 202
L ++ + A D K + LA + + E ++ ++S + L EL + N
Sbjct: 1427 DLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKN 1486
Query: 203 SL-KSLEVSE--EKANQRVEE 220
+ +SLE E ++ N+ ++E
Sbjct: 1487 AYEESLEHLETFKRENKNLQE 1507
Score = 51.6 bits (118), Expect = 3e-06
Identities = 38/170 (22%), Positives = 83/170 (48%), Gaps = 7/170 (4%)
Query: 45 ELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 104
E +K++A ++E+ K LE++ +E E+++ + E L +VQ +++L +EE
Sbjct: 844 EREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 903
Query: 105 RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 164
R + ++ + E N R + +EE +LT + ++ + D+
Sbjct: 904 RCDQLIKNKIQLEAKVKEMNE-------RLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
+ LA VE E E++VK+ +++ L+E + + K+L+ + ++A
Sbjct: 957 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 1006
Score = 51.6 bits (118), Expect = 3e-06
Identities = 69/310 (22%), Positives = 135/310 (43%), Gaps = 33/310 (10%)
Query: 5 KKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI-LNK- 61
+++M A + +K D+ ++ D L KV +E + K+ + E++ L++
Sbjct: 929 EEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEI 988
Query: 62 -NKLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQQKL 113
KL + K L+E +Q L A E +V L + K++Q +DLE S E+ + L
Sbjct: 989 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 1048
Query: 114 LEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
A++ + + ++ + LEN QQ +ER+ + +L ED ++ +KL
Sbjct: 1049 ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKL 1108
Query: 170 AFVEDELEVAEDRVKS---GDAKI----SELEEELKVVGNSLK----SLEVSEEKANQRV 218
++ +E E+ ++S AK+ S+L EL+ + L+ + V E +R
Sbjct: 1109 KELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKRE 1168
Query: 219 EEFXXXXXXXXXXXXXXXXXXXXXXK----TVKKLQKEVD---RLEDELGINKDRYKSLA 271
EF K +V +L +++D R++ +L K +K
Sbjct: 1169 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1228
Query: 272 DEMDSTFAEL 281
D++ S ++
Sbjct: 1229 DDVTSNMEQI 1238
Score = 51.6 bits (118), Expect = 3e-06
Identities = 42/285 (14%), Positives = 120/285 (42%), Gaps = 1/285 (0%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D+++ + A ++ A+ E + ++ N E QK++ ++ L
Sbjct: 1594 VDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDT 1653
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L+ A + ++ ++ + E L +++++ +E++E A+Q+L+E +
Sbjct: 1654 QIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERV 1713
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L N+ ++ + + QL +++EA +A+ K+ + A + +EL+ +
Sbjct: 1714 QLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQ 1773
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + +E+ +K + + L E ++ + +++++
Sbjct: 1774 DTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRN 1833
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K ++ + L + ++ L D +D ++ Y
Sbjct: 1834 AESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1878
Score = 51.2 bits (117), Expect = 4e-06
Identities = 43/260 (16%), Positives = 102/260 (39%), Gaps = 10/260 (3%)
Query: 11 MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ E+DN D + C+Q + ++ N R E E EL K ++E++
Sbjct: 891 VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSEL 950
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K ++ L + EK+ ATE +V L ++ ++E + K + Q+ +A
Sbjct: 951 KRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDL 1010
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
L + E+++D L L++ + + D + ++ L ++ + E
Sbjct: 1011 QAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLE 1070
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+ + D ++ + + EL + ++ + + ++++E
Sbjct: 1071 NDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELESERTARA 1130
Query: 241 XXXKTVKKLQKEVDRLEDEL 260
K L +E++ + + L
Sbjct: 1131 KVEKLRSDLSRELEEISERL 1150
Score = 44.0 bits (99), Expect = 6e-04
Identities = 29/184 (15%), Positives = 90/184 (48%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K++ ++ +LQ ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 1728 KKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1787
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LEN + +++R + ++++
Sbjct: 1788 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRI 1847
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + L ++D ++ + +VK+ + E EE+ + + ++ ++A
Sbjct: 1848 KELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAE 1907
Query: 216 QRVE 219
+R +
Sbjct: 1908 ERAD 1911
Score = 41.5 bits (93), Expect = 0.003
Identities = 49/227 (21%), Positives = 102/227 (44%), Gaps = 19/227 (8%)
Query: 12 KLEKDNAMDKADTCEQQAR-----DANLRAEKVNEEVRELQKKLAQVEEDL--------I 58
K E + KA++ Q R DA R E++ E ++L ++L + EE +
Sbjct: 1354 KAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSS 1413
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
L K K + ++E+ + + A AAL++K + ++ L + +++ +Q +L +Q+
Sbjct: 1414 LEKTK-HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQK 1472
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD---GKSDEVSRKLAFVEDE 175
A + L+N ++ E ++ + K + D G S + +L V +
Sbjct: 1473 EARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQ 1532
Query: 176 LEVAEDRVKSG--DAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
LE + ++S +A+ S EE K++ L+ ++ E + E+
Sbjct: 1533 LEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEK 1579
Score = 39.9 bits (89), Expect = 0.010
Identities = 35/166 (21%), Positives = 72/166 (43%), Gaps = 19/166 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTC-----EQQARDANLRAEKVNEEVRELQKKLAQVEE 55
++ +KK M+ + + +D+A+ ++Q + R ++ E+ QK+ A+ +
Sbjct: 1779 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVK 1838
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ ++ ++++ EE K L + V L KV+ + E++EE++ T K +
Sbjct: 1839 GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRK 1898
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
Q DE EER D +Q+ + R + D K
Sbjct: 1899 VQHELDEA--------------EERADIAESQVNKLRAKSRDIGTK 1930
Score = 31.5 bits (68), Expect = 3.5
Identities = 38/179 (21%), Positives = 78/179 (43%), Gaps = 10/179 (5%)
Query: 19 MDKADTCEQQARDANLRAEKVNEEVRE--LQKKLAQVEEDLILNKNKLEQANKDLEEKEK 76
M+K E Q +L + E L+KK A +L + L++ + LE+++
Sbjct: 1163 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1222
Query: 77 QLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ 136
+ + E+ + ++QI + E+ T + ++ E + A+E R L ++ +
Sbjct: 1223 EF---KLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAK 1279
Query: 137 DEERMDQLTNQLKEAR-LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 194
+ +L+ QL E L+++ GK + +ED E+ VK+ +A L+
Sbjct: 1280 LQTENGELSRQLDEKEALISQLTRGKLTYTQQ----LEDLKRQLEEEVKAKNALAHALQ 1334
>M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 62.1 bits (144), Expect = 2e-09
Identities = 47/206 (22%), Positives = 108/206 (52%), Gaps = 13/206 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKKM A ++ E + A+ + E++A+ A A + EE+++ Q A +E +
Sbjct: 1727 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 1783
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E +LE ++R+ + + + +
Sbjct: 1784 KN-MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRK 1842
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
+++ E + + ++ +D+L ++K + AE+A+ +++ K V+ E
Sbjct: 1843 SERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 1902
Query: 176 LEVAEDRVKSGDAKISELEEELKVVG 201
L+ AE+R ++++++L + + +G
Sbjct: 1903 LDEAEERADIAESQVNKLRAKSRDIG 1928
Score = 57.2 bits (132), Expect = 6e-08
Identities = 67/295 (22%), Positives = 126/295 (42%), Gaps = 26/295 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEK----VNEEVRELQKKLAQVE-- 54
+ +K+K++ K E +D + +Q A EK + +++ E + K + +
Sbjct: 1210 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRS 1269
Query: 55 -EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTA 109
DL + KL+ N +L +QL EA ++ L R QQ+ EDL++ E A
Sbjct: 1270 VNDLTSQRAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKA 1325
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGK 161
+ L A QSA + C +L + +++ E +L L +A +A+ DA +
Sbjct: 1326 KNALAHALQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQR 1382
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
++E+ + L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1383 TEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL 1442
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
++ QKE L EL K+ Y+ + +++
Sbjct: 1443 DKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1497
Score = 55.6 bits (128), Expect = 2e-07
Identities = 68/279 (24%), Positives = 130/279 (46%), Gaps = 25/279 (8%)
Query: 5 KKKMQAMKLE---KDNAMDKADTCEQQARD--ANLRAEK--VNEEVRELQKKLAQVEE-- 55
+K+M +MK E A++K++ ++ + +L EK + +V+ Q LA EE
Sbjct: 846 EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERC 905
Query: 56 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
LI NK +LE K++ E+ + AE+ A RK++ +L++ + K +
Sbjct: 906 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAK-V 964
Query: 115 EAQQSADENNRMCKVLENRAQQDE--ERMDQLTNQLKEARLLA-EDADGKSDEVSR---- 167
E ++ A E N++ + E A DE ++ + L+EA A +D + D+V+
Sbjct: 965 EKEKHATE-NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKA 1023
Query: 168 --KLAFVEDELEVAEDRVKSGDAKIS----ELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
KL D+LE + ++ K + +LE +LK+ S+ LE +++ ++R+++
Sbjct: 1024 KVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKK 1083
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
K +K+LQ ++ LE+EL
Sbjct: 1084 DFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1122
Score = 55.2 bits (127), Expect = 2e-07
Identities = 57/230 (24%), Positives = 114/230 (49%), Gaps = 23/230 (10%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 59
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1582
Query: 60 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 115
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1583 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 116 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 166
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
RKLA E EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 1699 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 1746
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 146 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 193
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 194 EEELKVVGNSLKSLEVSEEKANQ 216
+ E + +L+ + E N+
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLNE 1624
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/201 (22%), Positives = 87/201 (43%), Gaps = 4/201 (1%)
Query: 24 TCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 83
T QQ D + E+ + L L D L + + E+ + E ++ L+ +
Sbjct: 1307 TYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANS 1366
Query: 84 EVAALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 142
EVA K + + E+ EE Q+L EA+++ + N C LE + + ++
Sbjct: 1367 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE 1426
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 202
L ++ + A D K + LA + + E ++ ++S + L EL + N
Sbjct: 1427 DLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKN 1486
Query: 203 SL-KSLEVSE--EKANQRVEE 220
+ +SLE E ++ N+ ++E
Sbjct: 1487 AYEESLEHLETFKRENKNLQE 1507
Score = 51.6 bits (118), Expect = 3e-06
Identities = 38/170 (22%), Positives = 83/170 (48%), Gaps = 7/170 (4%)
Query: 45 ELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 104
E +K++A ++E+ K LE++ +E E+++ + E L +VQ +++L +EE
Sbjct: 844 EREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 903
Query: 105 RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 164
R + ++ + E N R + +EE +LT + ++ + D+
Sbjct: 904 RCDQLIKNKIQLEAKVKEMNE-------RLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
+ LA VE E E++VK+ +++ L+E + + K+L+ + ++A
Sbjct: 957 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 1006
Score = 51.6 bits (118), Expect = 3e-06
Identities = 69/310 (22%), Positives = 135/310 (43%), Gaps = 33/310 (10%)
Query: 5 KKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI-LNK- 61
+++M A + +K D+ ++ D L KV +E + K+ + E++ L++
Sbjct: 929 EEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEI 988
Query: 62 -NKLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQQKL 113
KL + K L+E +Q L A E +V L + K++Q +DLE S E+ + L
Sbjct: 989 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 1048
Query: 114 LEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
A++ + + ++ + LEN QQ +ER+ + +L ED ++ +KL
Sbjct: 1049 ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKL 1108
Query: 170 AFVEDELEVAEDRVKS---GDAKI----SELEEELKVVGNSLK----SLEVSEEKANQRV 218
++ +E E+ ++S AK+ S+L EL+ + L+ + V E +R
Sbjct: 1109 KELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKRE 1168
Query: 219 EEFXXXXXXXXXXXXXXXXXXXXXXK----TVKKLQKEVD---RLEDELGINKDRYKSLA 271
EF K +V +L +++D R++ +L K +K
Sbjct: 1169 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1228
Query: 272 DEMDSTFAEL 281
D++ S ++
Sbjct: 1229 DDVTSNMEQI 1238
Score = 51.6 bits (118), Expect = 3e-06
Identities = 42/285 (14%), Positives = 120/285 (42%), Gaps = 1/285 (0%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D+++ + A ++ A+ E + ++ N E QK++ ++ L
Sbjct: 1594 VDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDT 1653
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L+ A + ++ ++ + E L +++++ +E++E A+Q+L+E +
Sbjct: 1654 QIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERV 1713
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L N+ ++ + + QL +++EA +A+ K+ + A + +EL+ +
Sbjct: 1714 QLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQ 1773
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + +E+ +K + + L E ++ + +++++
Sbjct: 1774 DTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRN 1833
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K ++ + L + ++ L D +D ++ Y
Sbjct: 1834 AESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1878
Score = 51.2 bits (117), Expect = 4e-06
Identities = 43/260 (16%), Positives = 102/260 (39%), Gaps = 10/260 (3%)
Query: 11 MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ E+DN D + C+Q + ++ N R E E EL K ++E++
Sbjct: 891 VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSEL 950
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K ++ L + EK+ ATE +V L ++ ++E + K + Q+ +A
Sbjct: 951 KRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDL 1010
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
L + E+++D L L++ + + D + ++ L ++ + E
Sbjct: 1011 QAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLE 1070
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+ + D ++ + + EL + ++ + + ++++E
Sbjct: 1071 NDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELESERTARA 1130
Query: 241 XXXKTVKKLQKEVDRLEDEL 260
K L +E++ + + L
Sbjct: 1131 KVEKLRSDLSRELEEISERL 1150
Score = 44.0 bits (99), Expect = 6e-04
Identities = 29/184 (15%), Positives = 90/184 (48%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K++ ++ +LQ ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 1728 KKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1787
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LEN + +++R + ++++
Sbjct: 1788 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRI 1847
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + L ++D ++ + +VK+ + E EE+ + + ++ ++A
Sbjct: 1848 KELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAE 1907
Query: 216 QRVE 219
+R +
Sbjct: 1908 ERAD 1911
Score = 41.5 bits (93), Expect = 0.003
Identities = 49/227 (21%), Positives = 102/227 (44%), Gaps = 19/227 (8%)
Query: 12 KLEKDNAMDKADTCEQQAR-----DANLRAEKVNEEVRELQKKLAQVEEDL--------I 58
K E + KA++ Q R DA R E++ E ++L ++L + EE +
Sbjct: 1354 KAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSS 1413
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
L K K + ++E+ + + A AAL++K + ++ L + +++ +Q +L +Q+
Sbjct: 1414 LEKTK-HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQK 1472
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD---GKSDEVSRKLAFVEDE 175
A + L+N ++ E ++ + K + D G S + +L V +
Sbjct: 1473 EARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQ 1532
Query: 176 LEVAEDRVKSG--DAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
LE + ++S +A+ S EE K++ L+ ++ E + E+
Sbjct: 1533 LEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEK 1579
Score = 39.9 bits (89), Expect = 0.010
Identities = 35/166 (21%), Positives = 72/166 (43%), Gaps = 19/166 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTC-----EQQARDANLRAEKVNEEVRELQKKLAQVEE 55
++ +KK M+ + + +D+A+ ++Q + R ++ E+ QK+ A+ +
Sbjct: 1779 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVK 1838
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ ++ ++++ EE K L + V L KV+ + E++EE++ T K +
Sbjct: 1839 GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRK 1898
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
Q DE EER D +Q+ + R + D K
Sbjct: 1899 VQHELDEA--------------EERADIAESQVNKLRAKSRDIGTK 1930
Score = 31.5 bits (68), Expect = 3.5
Identities = 38/179 (21%), Positives = 78/179 (43%), Gaps = 10/179 (5%)
Query: 19 MDKADTCEQQARDANLRAEKVNEEVRE--LQKKLAQVEEDLILNKNKLEQANKDLEEKEK 76
M+K E Q +L + E L+KK A +L + L++ + LE+++
Sbjct: 1163 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1222
Query: 77 QLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ 136
+ + E+ + ++QI + E+ T + ++ E + A+E R L ++ +
Sbjct: 1223 EF---KLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAK 1279
Query: 137 DEERMDQLTNQLKEAR-LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 194
+ +L+ QL E L+++ GK + +ED E+ VK+ +A L+
Sbjct: 1280 LQTENGELSRQLDEKEALISQLTRGKLTYTQQ----LEDLKRQLEEEVKAKNALAHALQ 1334
>M55210-1|AAA59492.1| 1609|Homo sapiens laminin B2 chain protein.
Length = 1609
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 6/172 (3%)
Query: 33 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 92
N + NE+ RE Q+ L D KNK +A + +K T+T+AE +V
Sbjct: 1395 NQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEV 1454
Query: 93 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
++ ++ ++ A+++L Q AD++ M + AQ+ E + N +
Sbjct: 1455 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 1514
Query: 153 LLAED---ADGKSDEVS-RKLAFVEDELEVAEDRVKSG--DAKISELEEELK 198
+ D G+ D V KL +E L A+D +K D K+S+LE E K
Sbjct: 1515 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAK 1566
Score = 45.2 bits (102), Expect = 3e-04
Identities = 41/178 (23%), Positives = 72/178 (40%), Gaps = 7/178 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++ M+ +LE N ++K T +Q A RA+ E KK D + N
Sbjct: 1310 LREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKK----GRDTLQEAND 1365
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ KD + + T AE A RK+ I + + ++ E++ AQQ L A A E
Sbjct: 1366 ILNNLKDFDRRVND-NKTAAEEAL--RKIPAINQTITEANEKTREAQQALGSAAADATEA 1422
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E A ++ + + D D + + + ++L E EL+ +D
Sbjct: 1423 KNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKRKQD 1480
Score = 39.1 bits (87), Expect = 0.017
Identities = 35/254 (13%), Positives = 91/254 (35%), Gaps = 1/254 (0%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE-DLILNKNKLE 65
+++ + + + A + + E+QA + A++ ++ E+ +AQ+ D +N+
Sbjct: 1228 EIEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLENEAN 1287
Query: 66 QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
+ E E+ + + L ++ E +++ E+ T QQ + AD
Sbjct: 1288 NIKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKA 1347
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
+ + + + + + + N LK+ D ++E RK+ + + A ++ +
Sbjct: 1348 LAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAINQTITEANEKTRE 1407
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKT 245
+ + N E + K
Sbjct: 1408 AQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQ 1467
Query: 246 VKKLQKEVDRLEDE 259
+++ +KE+ R +D+
Sbjct: 1468 LQEAEKELKRKQDD 1481
Score = 37.5 bits (83), Expect = 0.053
Identities = 29/141 (20%), Positives = 57/141 (40%), Gaps = 4/141 (2%)
Query: 20 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 79
D+ E++ D A+ V + + L +L +V L ++L+ +EE
Sbjct: 1073 DRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAE 1132
Query: 80 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR--AQQD 137
A V R ++ +LEK+ + A + + + + D NN E R A++
Sbjct: 1133 QARAHVENTERLIEIASRELEKA--KVAAANVSVTQPESTGDPNNMTLLAEEARKLAERH 1190
Query: 138 EERMDQLTNQLKEARLLAEDA 158
++ D + K A + +A
Sbjct: 1191 KQEADDIVRVAKTANDTSTEA 1211
Score = 37.5 bits (83), Expect = 0.053
Identities = 45/207 (21%), Positives = 91/207 (43%), Gaps = 17/207 (8%)
Query: 31 DANL--RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEK--QLTATE---A 83
D NL R ++VN + +L + + N EQA +E E+ ++ + E A
Sbjct: 1096 DQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAEQARAHVENTERLIEIASRELEKA 1155
Query: 84 EVAALNRKVQQIEEDLEKSE-ERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERM 141
+VAA N V Q E + + +KL E +Q AD+ R+ K + + + +
Sbjct: 1156 KVAAANVSVTQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLL 1215
Query: 142 -------DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 194
+Q +++E E A S ++ ++ A V +E + A D+ A +++L
Sbjct: 1216 LRTLAGENQTAFEIEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLS 1275
Query: 195 E-ELKVVGNSLKSLEVSEEKANQRVEE 220
+ + + N ++++ E Q +++
Sbjct: 1276 PLDSETLENEANNIKMEAENLEQLIDQ 1302
Score = 32.3 bits (70), Expect = 2.0
Identities = 41/216 (18%), Positives = 82/216 (37%), Gaps = 13/216 (6%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D + + A K + A K Q+A D + + V + + + +
Sbjct: 1336 DQLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAIN 1395
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT-----AQQKLLEA 116
+ +AN+ E ++ L + A+ K + E + + +++ T A++ E
Sbjct: 1396 QTITEANEKTREAQQALGSAAADATEAKNKAHEAER-IASAVQKNATSTKAEAERTFAEV 1454
Query: 117 QQSADENNRMCKVLE------NRAQQDEERMDQLTNQLKEARLLAE-DADGKSDEVSRKL 169
+E N M K L+ R Q D ++ + +A AE +A + V+ L
Sbjct: 1455 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 1514
Query: 170 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
+ + D LE K++E+E L + +K
Sbjct: 1515 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMK 1550
>M27654-1|AAA59489.1| 217|Homo sapiens laminin B2 protein.
Length = 217
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 6/172 (3%)
Query: 33 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 92
N + NE+ RE Q+ L D KNK +A + +K T+T+AE +V
Sbjct: 3 NQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEV 62
Query: 93 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
++ ++ ++ A+++L Q AD++ M + AQ+ E + N +
Sbjct: 63 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 122
Query: 153 LLAED---ADGKSDEVS-RKLAFVEDELEVAEDRVKSG--DAKISELEEELK 198
+ D G+ D V KL +E L A+D +K D K+S+LE E K
Sbjct: 123 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAK 174
Score = 31.1 bits (67), Expect = 4.6
Identities = 23/123 (18%), Positives = 56/123 (45%), Gaps = 4/123 (3%)
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
A+N+ + + E ++++ G+A EA+ A E R+ ++ A + ++
Sbjct: 1 AINQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFA 60
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL--KVVGNSL 204
++ + + + E ++L +D+ + +D + +G A + E E+ + NS+
Sbjct: 61 EVTDLDNEVNNMLKQLQEAEKELKRKQDDAD--QDMMMAGMASQAAQEAEINARKAKNSV 118
Query: 205 KSL 207
SL
Sbjct: 119 TSL 121
>M25139-1|AAA60385.1| 611|Homo sapiens myosin heavy chain
beta-subunit protein.
Length = 611
Score = 62.1 bits (144), Expect = 2e-09
Identities = 47/206 (22%), Positives = 108/206 (52%), Gaps = 13/206 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKKM A ++ E + A+ + E++A+ A A + EE+++ Q A +E +
Sbjct: 403 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 459
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E +LE ++R+ + + + +
Sbjct: 460 KN-MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRK 518
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
+++ E + + ++ +D+L ++K + AE+A+ +++ K V+ E
Sbjct: 519 SERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 578
Query: 176 LEVAEDRVKSGDAKISELEEELKVVG 201
L+ AE+R ++++++L + + +G
Sbjct: 579 LDEAEERADIAESQVNKLRAKSRDIG 604
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 98 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 157
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 158 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 217
Query: 146 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 193
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 218 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 277
Query: 194 EEELKVVGNSLKSLEVSEEKANQ 216
+ E + +L+ + E N+
Sbjct: 278 DAETRSRNEALRVKKKMEGDLNE 300
Score = 54.0 bits (124), Expect = 6e-07
Identities = 51/276 (18%), Positives = 120/276 (43%), Gaps = 19/276 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDL-I 58
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E++
Sbjct: 202 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 261
Query: 59 LNKNKLE-----QANKDLEEK------------EKQLTATEAEVAALNRKVQQIEEDLEK 101
+N L Q + D E + E L E +++ NR + ++ ++
Sbjct: 262 AKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS 321
Query: 102 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
+ Q +L +A ++ D+ ++E R + +++L +++ + AD +
Sbjct: 322 LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADRE 381
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
E S ++ + + ++ K DA +S+L+ E++ ++ E +KA
Sbjct: 382 LIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMM 441
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLE 257
+T+K LQ +D E
Sbjct: 442 AEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 477
Score = 48.4 bits (110), Expect = 3e-05
Identities = 51/264 (19%), Positives = 107/264 (40%), Gaps = 8/264 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRE-LQKKLAQVEEDLILNKN 62
+ +K + M+ K N + D+ Q + DA R+ V++ ++ L ++E L
Sbjct: 252 LAEKDEEMEQAKRNHLRVVDSL-QTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANR 310
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+A K ++ + L T+ ++ R ++E++ E R+ Q +L E + ++
Sbjct: 311 MAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 370
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
R K+ + + ER+ L +Q + D ++ ++ E AE++
Sbjct: 371 TERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEK 430
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXX 242
K + + EELK ++ LE ++ Q +++
Sbjct: 431 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDL------QHRLDEAEQIALKGG 484
Query: 243 XKTVKKLQKEVDRLEDELGINKDR 266
K ++KL+ V LE+EL + R
Sbjct: 485 KKQLQKLEARVRELENELEAEQKR 508
Score = 47.2 bits (107), Expect = 7e-05
Identities = 40/179 (22%), Positives = 79/179 (44%), Gaps = 4/179 (2%)
Query: 46 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ-QIEEDLEKSEE 104
L L D L + + E+ + E ++ L+ +EVA K + + E+ EE
Sbjct: 5 LAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEE 64
Query: 105 RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 164
Q+L EA+++ + N C LE + + ++ L ++ + A D K
Sbjct: 65 AKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRN 124
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL-KSLEVSE--EKANQRVEE 220
+ LA + + E ++ ++S + L EL + N+ +SLE E ++ N+ ++E
Sbjct: 125 FDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQE 183
Score = 44.0 bits (99), Expect = 6e-04
Identities = 29/184 (15%), Positives = 90/184 (48%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K++ ++ +LQ ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 404 KKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 463
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LEN + +++R + ++++
Sbjct: 464 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRI 523
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + L ++D ++ + +VK+ + E EE+ + + ++ ++A
Sbjct: 524 KELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAE 583
Query: 216 QRVE 219
+R +
Sbjct: 584 ERAD 587
Score = 41.5 bits (93), Expect = 0.003
Identities = 49/227 (21%), Positives = 102/227 (44%), Gaps = 19/227 (8%)
Query: 12 KLEKDNAMDKADTCEQQAR-----DANLRAEKVNEEVRELQKKLAQVEEDL--------I 58
K E + KA++ Q R DA R E++ E ++L ++L + EE +
Sbjct: 30 KAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSS 89
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
L K K + ++E+ + + A AAL++K + ++ L + +++ +Q +L +Q+
Sbjct: 90 LEKTK-HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQK 148
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD---GKSDEVSRKLAFVEDE 175
A + L+N ++ E ++ + K + D G S + +L V +
Sbjct: 149 EARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQ 208
Query: 176 LEVAEDRVKSG--DAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
LE + ++S +A+ S EE K++ L+ ++ E + E+
Sbjct: 209 LEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEK 255
Score = 39.9 bits (89), Expect = 0.010
Identities = 35/166 (21%), Positives = 72/166 (43%), Gaps = 19/166 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTC-----EQQARDANLRAEKVNEEVRELQKKLAQVEE 55
++ +KK M+ + + +D+A+ ++Q + R ++ E+ QK+ A+ +
Sbjct: 455 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVK 514
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ ++ ++++ EE K L + V L KV+ + E++EE++ T K +
Sbjct: 515 GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRK 574
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
Q DE EER D +Q+ + R + D K
Sbjct: 575 VQHELDEA--------------EERADIAESQVNKLRAKSRDIGTK 606
>M21665-1|AAA36345.1| 524|Homo sapiens protein ( Human beta-myosin
heavy chain mRNA, 3' end. ).
Length = 524
Score = 62.1 bits (144), Expect = 2e-09
Identities = 47/206 (22%), Positives = 108/206 (52%), Gaps = 13/206 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKKM A ++ E + A+ + E++A+ A A + EE+++ Q A +E +
Sbjct: 316 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 372
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E +LE ++R+ + + + +
Sbjct: 373 KN-MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRK 431
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
+++ E + + ++ +D+L ++K + AE+A+ +++ K V+ E
Sbjct: 432 SERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 491
Query: 176 LEVAEDRVKSGDAKISELEEELKVVG 201
L+ AE+R ++++++L + + +G
Sbjct: 492 LDEAEERADIAESQVNKLRAKSRDIG 517
Score = 54.0 bits (124), Expect = 6e-07
Identities = 39/191 (20%), Positives = 80/191 (41%), Gaps = 2/191 (1%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 11 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 70
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 71 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 130
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
+ L+EA E +GK + +L F + + E+ + + + L+VV +
Sbjct: 131 SALEEAEASLEHEEGKI--LRAQLEFNQIKAEIERNVAEKDEEMEQAKRNHLRVVDSLQT 188
Query: 206 SLEVSEEKANQ 216
SL+ N+
Sbjct: 189 SLDAETRSRNE 199
Score = 52.0 bits (119), Expect = 2e-06
Identities = 55/230 (23%), Positives = 113/230 (49%), Gaps = 23/230 (10%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 59
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++ +A+ +E+
Sbjct: 115 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERNVAEKDEE--- 171
Query: 60 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 115
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 172 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 227
Query: 116 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 166
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 228 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 287
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
RKLA E EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 288 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 335
Score = 51.6 bits (118), Expect = 3e-06
Identities = 42/285 (14%), Positives = 120/285 (42%), Gaps = 1/285 (0%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D+++ + A ++ A+ E + ++ N E QK++ ++ L
Sbjct: 183 VDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDT 242
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L+ A + ++ ++ + E L +++++ +E++E A+Q+L+E +
Sbjct: 243 QIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERV 302
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L N+ ++ + + QL +++EA +A+ K+ + A + +EL+ +
Sbjct: 303 QLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQ 362
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + +E+ +K + + L E ++ + +++++
Sbjct: 363 DTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRN 422
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K ++ + L + ++ L D +D ++ Y
Sbjct: 423 AESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 467
Score = 44.0 bits (99), Expect = 6e-04
Identities = 29/184 (15%), Positives = 90/184 (48%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K++ ++ +LQ ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 317 KKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 376
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LEN + +++R + ++++
Sbjct: 377 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRI 436
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + L ++D ++ + +VK+ + E EE+ + + ++ ++A
Sbjct: 437 KELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAE 496
Query: 216 QRVE 219
+R +
Sbjct: 497 ERAD 500
Score = 39.9 bits (89), Expect = 0.010
Identities = 35/166 (21%), Positives = 72/166 (43%), Gaps = 19/166 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTC-----EQQARDANLRAEKVNEEVRELQKKLAQVEE 55
++ +KK M+ + + +D+A+ ++Q + R ++ E+ QK+ A+ +
Sbjct: 368 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVK 427
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ ++ ++++ EE K L + V L KV+ + E++EE++ T K +
Sbjct: 428 GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRK 487
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
Q DE EER D +Q+ + R + D K
Sbjct: 488 VQHELDEA--------------EERADIAESQVNKLRAKSRDIGTK 519
>M17712-1|AAA36343.1| 543|Homo sapiens protein ( Human cardiac
myosin heavy chain mRNA, 3' end. ).
Length = 543
Score = 62.1 bits (144), Expect = 2e-09
Identities = 47/206 (22%), Positives = 108/206 (52%), Gaps = 13/206 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKKM A ++ E + A+ + E++A+ A A + EE+++ Q A +E +
Sbjct: 335 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 391
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E +LE ++R+ + + + +
Sbjct: 392 KN-MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRK 450
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
+++ E + + ++ +D+L ++K + AE+A+ +++ K V+ E
Sbjct: 451 SERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 510
Query: 176 LEVAEDRVKSGDAKISELEEELKVVG 201
L+ AE+R ++++++L + + +G
Sbjct: 511 LDEAEERADIAESQVNKLRAKSRDIG 536
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 30 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 89
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 90 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 149
Query: 146 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 193
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 150 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 209
Query: 194 EEELKVVGNSLKSLEVSEEKANQ 216
+ E + +L+ + E N+
Sbjct: 210 DAETRSRNEALRVKKKMEGDLNE 232
Score = 54.0 bits (124), Expect = 6e-07
Identities = 51/276 (18%), Positives = 120/276 (43%), Gaps = 19/276 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDL-I 58
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E++
Sbjct: 134 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 193
Query: 59 LNKNKLE-----QANKDLEEK------------EKQLTATEAEVAALNRKVQQIEEDLEK 101
+N L Q + D E + E L E +++ NR + ++ ++
Sbjct: 194 AKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS 253
Query: 102 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
+ Q +L +A ++ D+ ++E R + +++L +++ + AD +
Sbjct: 254 LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADRE 313
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
E S ++ + + ++ K DA +S+L+ E++ ++ E +KA
Sbjct: 314 LIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMM 373
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLE 257
+T+K LQ +D E
Sbjct: 374 AEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 409
Score = 48.4 bits (110), Expect = 3e-05
Identities = 41/238 (17%), Positives = 100/238 (42%), Gaps = 7/238 (2%)
Query: 27 QQARDANLRAEKVNEEVRELQK---KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 83
Q+ ++A E VN + L+K +L EDL+++ + A L++K++ A
Sbjct: 3 QRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILA 62
Query: 84 EVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQ 143
E +K ++ + +LE S++ + + +L + + + +E+ + + + +E +
Sbjct: 63 E---WKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISD 119
Query: 144 LTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNS 203
LT QL + + + ++ + ++ LE AE ++ + KI + E +
Sbjct: 120 LTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAE 179
Query: 204 L-KSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
+ + L +E+ Q + KK++ +++ +E +L
Sbjct: 180 IERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQL 237
Score = 48.4 bits (110), Expect = 3e-05
Identities = 51/264 (19%), Positives = 107/264 (40%), Gaps = 8/264 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRE-LQKKLAQVEEDLILNKN 62
+ +K + M+ K N + D+ Q + DA R+ V++ ++ L ++E L
Sbjct: 184 LAEKDEEMEQAKRNHLRVVDSL-QTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANR 242
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+A K ++ + L T+ ++ R ++E++ E R+ Q +L E + ++
Sbjct: 243 MAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 302
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
R K+ + + ER+ L +Q + D ++ ++ E AE++
Sbjct: 303 TERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEK 362
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXX 242
K + + EELK ++ LE ++ Q +++
Sbjct: 363 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDL------QHRLDEAEQIALKGG 416
Query: 243 XKTVKKLQKEVDRLEDELGINKDR 266
K ++KL+ V LE+EL + R
Sbjct: 417 KKQLQKLEARVRELENELEAEQKR 440
Score = 44.0 bits (99), Expect = 6e-04
Identities = 29/184 (15%), Positives = 90/184 (48%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K++ ++ +LQ ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 336 KKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 395
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LEN + +++R + ++++
Sbjct: 396 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRI 455
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + L ++D ++ + +VK+ + E EE+ + + ++ ++A
Sbjct: 456 KELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAE 515
Query: 216 QRVE 219
+R +
Sbjct: 516 ERAD 519
Score = 39.9 bits (89), Expect = 0.010
Identities = 35/166 (21%), Positives = 72/166 (43%), Gaps = 19/166 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTC-----EQQARDANLRAEKVNEEVRELQKKLAQVEE 55
++ +KK M+ + + +D+A+ ++Q + R ++ E+ QK+ A+ +
Sbjct: 387 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVK 446
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ ++ ++++ EE K L + V L KV+ + E++EE++ T K +
Sbjct: 447 GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRK 506
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
Q DE EER D +Q+ + R + D K
Sbjct: 507 VQHELDEA--------------EERADIAESQVNKLRAKSRDIGTK 538
Score = 32.3 bits (70), Expect = 2.0
Identities = 38/188 (20%), Positives = 84/188 (44%), Gaps = 14/188 (7%)
Query: 46 LQKKLAQVEEDL--------ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 97
L ++L + EE + L K K + ++E+ + + A AAL++K + ++
Sbjct: 1 LAQRLQEAEEAVEAVNAKCSSLEKTK-HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDK 59
Query: 98 DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 157
L + +++ +Q +L +Q+ A + L+N ++ E ++ + K + D
Sbjct: 60 ILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISD 119
Query: 158 AD---GKSDEVSRKLAFVEDELEVAEDRVKSG--DAKISELEEELKVVGNSLKSLEVSEE 212
G S + +L V +LE + ++S +A+ S EE K++ L+ ++ E
Sbjct: 120 LTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAE 179
Query: 213 KANQRVEE 220
+ E+
Sbjct: 180 IERKLAEK 187
>J03202-1|AAA59488.1| 1609|Homo sapiens LAMB2 protein.
Length = 1609
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 6/172 (3%)
Query: 33 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 92
N + NE+ RE Q+ L D KNK +A + +K T+T+AE +V
Sbjct: 1395 NQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEV 1454
Query: 93 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
++ ++ ++ A+++L Q AD++ M + AQ+ E + N +
Sbjct: 1455 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 1514
Query: 153 LLAED---ADGKSDEVS-RKLAFVEDELEVAEDRVKSG--DAKISELEEELK 198
+ D G+ D V KL +E L A+D +K D K+S+LE E K
Sbjct: 1515 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAK 1566
Score = 45.2 bits (102), Expect = 3e-04
Identities = 41/178 (23%), Positives = 72/178 (40%), Gaps = 7/178 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++ M+ +LE N ++K T +Q A RA+ E KK D + N
Sbjct: 1310 LREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKK----GRDTLQEAND 1365
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ KD + + T AE A RK+ I + + ++ E++ AQQ L A A E
Sbjct: 1366 ILNNLKDFDRRVND-NKTAAEEAL--RKIPAINQTITEANEKTREAQQALGSAAADATEA 1422
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E A ++ + + D D + + + ++L E EL+ +D
Sbjct: 1423 KNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKRKQD 1480
Score = 39.1 bits (87), Expect = 0.017
Identities = 35/254 (13%), Positives = 91/254 (35%), Gaps = 1/254 (0%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE-DLILNKNKLE 65
+++ + + + A + + E+QA + A++ ++ E+ +AQ+ D +N+
Sbjct: 1228 EIEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLENEAN 1287
Query: 66 QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
+ E E+ + + L ++ E +++ E+ T QQ + AD
Sbjct: 1288 NIKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKA 1347
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
+ + + + + + + N LK+ D ++E RK+ + + A ++ +
Sbjct: 1348 LAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAINQTITEANEKTRE 1407
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKT 245
+ + N E + K
Sbjct: 1408 AQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQ 1467
Query: 246 VKKLQKEVDRLEDE 259
+++ +KE+ R +D+
Sbjct: 1468 LQEAEKELKRKQDD 1481
Score = 37.5 bits (83), Expect = 0.053
Identities = 29/141 (20%), Positives = 57/141 (40%), Gaps = 4/141 (2%)
Query: 20 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 79
D+ E++ D A+ V + + L +L +V L ++L+ +EE
Sbjct: 1073 DRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAE 1132
Query: 80 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR--AQQD 137
A V R ++ +LEK+ + A + + + + D NN E R A++
Sbjct: 1133 QARAHVENTERLIEIASRELEKA--KVAAANVSVTQPESTGDPNNMTLLAEEARKLAERH 1190
Query: 138 EERMDQLTNQLKEARLLAEDA 158
++ D + K A + +A
Sbjct: 1191 KQEADDIVRVAKTANDTSTEA 1211
Score = 37.5 bits (83), Expect = 0.053
Identities = 45/207 (21%), Positives = 91/207 (43%), Gaps = 17/207 (8%)
Query: 31 DANL--RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEK--QLTATE---A 83
D NL R ++VN + +L + + N EQA +E E+ ++ + E A
Sbjct: 1096 DQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAEQARAHVENTERLIEIASRELEKA 1155
Query: 84 EVAALNRKVQQIEEDLEKSE-ERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERM 141
+VAA N V Q E + + +KL E +Q AD+ R+ K + + + +
Sbjct: 1156 KVAAANVSVTQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLL 1215
Query: 142 -------DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 194
+Q +++E E A S ++ ++ A V +E + A D+ A +++L
Sbjct: 1216 LRTLAGENQTAFEIEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLS 1275
Query: 195 E-ELKVVGNSLKSLEVSEEKANQRVEE 220
+ + + N ++++ E Q +++
Sbjct: 1276 PLDSETLENEANNIKMEAENLEQLIDQ 1302
Score = 32.3 bits (70), Expect = 2.0
Identities = 41/216 (18%), Positives = 82/216 (37%), Gaps = 13/216 (6%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D + + A K + A K Q+A D + + V + + + +
Sbjct: 1336 DQLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAIN 1395
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT-----AQQKLLEA 116
+ +AN+ E ++ L + A+ K + E + + +++ T A++ E
Sbjct: 1396 QTITEANEKTREAQQALGSAAADATEAKNKAHEAER-IASAVQKNATSTKAEAERTFAEV 1454
Query: 117 QQSADENNRMCKVLE------NRAQQDEERMDQLTNQLKEARLLAE-DADGKSDEVSRKL 169
+E N M K L+ R Q D ++ + +A AE +A + V+ L
Sbjct: 1455 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 1514
Query: 170 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
+ + D LE K++E+E L + +K
Sbjct: 1515 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMK 1550
>EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 62.1 bits (144), Expect = 2e-09
Identities = 47/206 (22%), Positives = 108/206 (52%), Gaps = 13/206 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKKM A ++ E + A+ + E++A+ A A + EE+++ Q A +E +
Sbjct: 1727 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 1783
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E +LE ++R+ + + + +
Sbjct: 1784 KN-MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRK 1842
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
+++ E + + ++ +D+L ++K + AE+A+ +++ K V+ E
Sbjct: 1843 SERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 1902
Query: 176 LEVAEDRVKSGDAKISELEEELKVVG 201
L+ AE+R ++++++L + + +G
Sbjct: 1903 LDEAEERADIAESQVNKLRAKSRDIG 1928
Score = 57.2 bits (132), Expect = 6e-08
Identities = 67/295 (22%), Positives = 126/295 (42%), Gaps = 26/295 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEK----VNEEVRELQKKLAQVE-- 54
+ +K+K++ K E +D + +Q A EK + +++ E + K + +
Sbjct: 1210 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRS 1269
Query: 55 -EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTA 109
DL + KL+ N +L +QL EA ++ L R QQ+ EDL++ E A
Sbjct: 1270 VNDLTSQRAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKA 1325
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGK 161
+ L A QSA + C +L + +++ E +L L +A +A+ DA +
Sbjct: 1326 KNALAHALQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQR 1382
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
++E+ + L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1383 TEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL 1442
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
++ QKE L EL K+ Y+ + +++
Sbjct: 1443 DKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1497
Score = 55.6 bits (128), Expect = 2e-07
Identities = 68/279 (24%), Positives = 130/279 (46%), Gaps = 25/279 (8%)
Query: 5 KKKMQAMKLE---KDNAMDKADTCEQQARD--ANLRAEK--VNEEVRELQKKLAQVEE-- 55
+K+M +MK E A++K++ ++ + +L EK + +V+ Q LA EE
Sbjct: 846 EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERC 905
Query: 56 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
LI NK +LE K++ E+ + AE+ A RK++ +L++ + K +
Sbjct: 906 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAK-V 964
Query: 115 EAQQSADENNRMCKVLENRAQQDE--ERMDQLTNQLKEARLLA-EDADGKSDEVSR---- 167
E ++ A E N++ + E A DE ++ + L+EA A +D + D+V+
Sbjct: 965 EKEKHATE-NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKA 1023
Query: 168 --KLAFVEDELEVAEDRVKSGDAKIS----ELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
KL D+LE + ++ K + +LE +LK+ S+ LE +++ ++R+++
Sbjct: 1024 KVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKK 1083
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
K +K+LQ ++ LE+EL
Sbjct: 1084 DFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1122
Score = 55.2 bits (127), Expect = 2e-07
Identities = 57/230 (24%), Positives = 114/230 (49%), Gaps = 23/230 (10%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 59
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1582
Query: 60 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 115
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1583 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 116 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 166
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
RKLA E EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 1699 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 1746
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 146 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 193
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 194 EEELKVVGNSLKSLEVSEEKANQ 216
+ E + +L+ + E N+
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLNE 1624
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/201 (22%), Positives = 87/201 (43%), Gaps = 4/201 (1%)
Query: 24 TCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 83
T QQ D + E+ + L L D L + + E+ + E ++ L+ +
Sbjct: 1307 TYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANS 1366
Query: 84 EVAALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 142
EVA K + + E+ EE Q+L EA+++ + N C LE + + ++
Sbjct: 1367 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE 1426
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 202
L ++ + A D K + LA + + E ++ ++S + L EL + N
Sbjct: 1427 DLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKN 1486
Query: 203 SL-KSLEVSE--EKANQRVEE 220
+ +SLE E ++ N+ ++E
Sbjct: 1487 AYEESLEHLETFKRENKNLQE 1507
Score = 51.6 bits (118), Expect = 3e-06
Identities = 38/170 (22%), Positives = 83/170 (48%), Gaps = 7/170 (4%)
Query: 45 ELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 104
E +K++A ++E+ K LE++ +E E+++ + E L +VQ +++L +EE
Sbjct: 844 EREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 903
Query: 105 RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 164
R + ++ + E N R + +EE +LT + ++ + D+
Sbjct: 904 RCDQLIKNKIQLEAKVKEMNE-------RLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
+ LA VE E E++VK+ +++ L+E + + K+L+ + ++A
Sbjct: 957 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 1006
Score = 51.6 bits (118), Expect = 3e-06
Identities = 42/285 (14%), Positives = 120/285 (42%), Gaps = 1/285 (0%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D+++ + A ++ A+ E + ++ N E QK++ ++ L
Sbjct: 1594 VDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDT 1653
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L+ A + ++ ++ + E L +++++ +E++E A+Q+L+E +
Sbjct: 1654 QIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERV 1713
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L N+ ++ + + QL +++EA +A+ K+ + A + +EL+ +
Sbjct: 1714 QLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQ 1773
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + +E+ +K + + L E ++ + +++++
Sbjct: 1774 DTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRN 1833
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K ++ + L + ++ L D +D ++ Y
Sbjct: 1834 AESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1878
Score = 51.2 bits (117), Expect = 4e-06
Identities = 43/260 (16%), Positives = 102/260 (39%), Gaps = 10/260 (3%)
Query: 11 MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ E+DN D + C+Q + ++ N R E E EL K ++E++
Sbjct: 891 VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSEL 950
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K ++ L + EK+ ATE +V L ++ ++E + K + Q+ +A
Sbjct: 951 KRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDL 1010
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
L + E+++D L L++ + + D + ++ L ++ + E
Sbjct: 1011 QAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLE 1070
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+ + D ++ + + EL + ++ + + ++++E
Sbjct: 1071 NDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARA 1130
Query: 241 XXXKTVKKLQKEVDRLEDEL 260
K L +E++ + + L
Sbjct: 1131 KVEKLRSDLSRELEEISERL 1150
Score = 50.8 bits (116), Expect = 5e-06
Identities = 68/310 (21%), Positives = 135/310 (43%), Gaps = 33/310 (10%)
Query: 5 KKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI-LNK- 61
+++M A + +K D+ ++ D L KV +E + K+ + E++ L++
Sbjct: 929 EEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEI 988
Query: 62 -NKLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQQKL 113
KL + K L+E +Q L A E +V L + K++Q +DLE S E+ + L
Sbjct: 989 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 1048
Query: 114 LEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
A++ + + ++ + LEN QQ +ER+ + +L ED ++ +KL
Sbjct: 1049 ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKL 1108
Query: 170 AFVEDELEVAEDRV---KSGDAKI----SELEEELKVVGNSLK----SLEVSEEKANQRV 218
++ +E E+ + ++ AK+ S+L EL+ + L+ + V E +R
Sbjct: 1109 KELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKRE 1168
Query: 219 EEFXXXXXXXXXXXXXXXXXXXXXXK----TVKKLQKEVD---RLEDELGINKDRYKSLA 271
EF K +V +L +++D R++ +L K +K
Sbjct: 1169 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1228
Query: 272 DEMDSTFAEL 281
D++ S ++
Sbjct: 1229 DDVTSNMEQI 1238
Score = 44.0 bits (99), Expect = 6e-04
Identities = 29/184 (15%), Positives = 90/184 (48%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K++ ++ +LQ ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 1728 KKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1787
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LEN + +++R + ++++
Sbjct: 1788 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRI 1847
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + L ++D ++ + +VK+ + E EE+ + + ++ ++A
Sbjct: 1848 KELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAE 1907
Query: 216 QRVE 219
+R +
Sbjct: 1908 ERAD 1911
Score = 41.5 bits (93), Expect = 0.003
Identities = 49/227 (21%), Positives = 102/227 (44%), Gaps = 19/227 (8%)
Query: 12 KLEKDNAMDKADTCEQQAR-----DANLRAEKVNEEVRELQKKLAQVEEDL--------I 58
K E + KA++ Q R DA R E++ E ++L ++L + EE +
Sbjct: 1354 KAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSS 1413
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
L K K + ++E+ + + A AAL++K + ++ L + +++ +Q +L +Q+
Sbjct: 1414 LEKTK-HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQK 1472
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD---GKSDEVSRKLAFVEDE 175
A + L+N ++ E ++ + K + D G S + +L V +
Sbjct: 1473 EARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQ 1532
Query: 176 LEVAEDRVKSG--DAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
LE + ++S +A+ S EE K++ L+ ++ E + E+
Sbjct: 1533 LEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEK 1579
Score = 39.9 bits (89), Expect = 0.010
Identities = 35/166 (21%), Positives = 72/166 (43%), Gaps = 19/166 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTC-----EQQARDANLRAEKVNEEVRELQKKLAQVEE 55
++ +KK M+ + + +D+A+ ++Q + R ++ E+ QK+ A+ +
Sbjct: 1779 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVK 1838
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ ++ ++++ EE K L + V L KV+ + E++EE++ T K +
Sbjct: 1839 GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRK 1898
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
Q DE EER D +Q+ + R + D K
Sbjct: 1899 VQHELDEA--------------EERADIAESQVNKLRAKSRDIGTK 1930
Score = 31.5 bits (68), Expect = 3.5
Identities = 38/179 (21%), Positives = 78/179 (43%), Gaps = 10/179 (5%)
Query: 19 MDKADTCEQQARDANLRAEKVNEEVRE--LQKKLAQVEEDLILNKNKLEQANKDLEEKEK 76
M+K E Q +L + E L+KK A +L + L++ + LE+++
Sbjct: 1163 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1222
Query: 77 QLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ 136
+ + E+ + ++QI + E+ T + ++ E + A+E R L ++ +
Sbjct: 1223 EF---KLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAK 1279
Query: 137 DEERMDQLTNQLKEAR-LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 194
+ +L+ QL E L+++ GK + +ED E+ VK+ +A L+
Sbjct: 1280 LQTENGELSRQLDEKEALISQLTRGKLTYTQQ----LEDLKRQLEEEVKAKNALAHALQ 1334
>BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 62.1 bits (144), Expect = 2e-09
Identities = 47/206 (22%), Positives = 108/206 (52%), Gaps = 13/206 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKKM A ++ E + A+ + E++A+ A A + EE+++ Q A +E +
Sbjct: 1727 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 1783
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E +LE ++R+ + + + +
Sbjct: 1784 KN-MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRK 1842
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
+++ E + + ++ +D+L ++K + AE+A+ +++ K V+ E
Sbjct: 1843 SERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 1902
Query: 176 LEVAEDRVKSGDAKISELEEELKVVG 201
L+ AE+R ++++++L + + +G
Sbjct: 1903 LDEAEERADIAESQVNKLRAKSRDIG 1928
Score = 57.2 bits (132), Expect = 6e-08
Identities = 67/295 (22%), Positives = 126/295 (42%), Gaps = 26/295 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEK----VNEEVRELQKKLAQVE-- 54
+ +K+K++ K E +D + +Q A EK + +++ E + K + +
Sbjct: 1210 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRS 1269
Query: 55 -EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTA 109
DL + KL+ N +L +QL EA ++ L R QQ+ EDL++ E A
Sbjct: 1270 VNDLTSQRAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKA 1325
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGK 161
+ L A QSA + C +L + +++ E +L L +A +A+ DA +
Sbjct: 1326 KNALAHALQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQR 1382
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
++E+ + L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1383 TEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL 1442
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
++ QKE L EL K+ Y+ + +++
Sbjct: 1443 DKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1497
Score = 55.6 bits (128), Expect = 2e-07
Identities = 68/279 (24%), Positives = 130/279 (46%), Gaps = 25/279 (8%)
Query: 5 KKKMQAMKLE---KDNAMDKADTCEQQARD--ANLRAEK--VNEEVRELQKKLAQVEE-- 55
+K+M +MK E A++K++ ++ + +L EK + +V+ Q LA EE
Sbjct: 846 EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERC 905
Query: 56 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
LI NK +LE K++ E+ + AE+ A RK++ +L++ + K +
Sbjct: 906 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAK-V 964
Query: 115 EAQQSADENNRMCKVLENRAQQDE--ERMDQLTNQLKEARLLA-EDADGKSDEVSR---- 167
E ++ A E N++ + E A DE ++ + L+EA A +D + D+V+
Sbjct: 965 EKEKHATE-NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKA 1023
Query: 168 --KLAFVEDELEVAEDRVKSGDAKIS----ELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
KL D+LE + ++ K + +LE +LK+ S+ LE +++ ++R+++
Sbjct: 1024 KVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKK 1083
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
K +K+LQ ++ LE+EL
Sbjct: 1084 DFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1122
Score = 55.2 bits (127), Expect = 2e-07
Identities = 57/230 (24%), Positives = 114/230 (49%), Gaps = 23/230 (10%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 59
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1582
Query: 60 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 115
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1583 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 116 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 166
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
RKLA E EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 1699 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 1746
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 146 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 193
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 194 EEELKVVGNSLKSLEVSEEKANQ 216
+ E + +L+ + E N+
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLNE 1624
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/201 (22%), Positives = 87/201 (43%), Gaps = 4/201 (1%)
Query: 24 TCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 83
T QQ D + E+ + L L D L + + E+ + E ++ L+ +
Sbjct: 1307 TYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANS 1366
Query: 84 EVAALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 142
EVA K + + E+ EE Q+L EA+++ + N C LE + + ++
Sbjct: 1367 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE 1426
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 202
L ++ + A D K + LA + + E ++ ++S + L EL + N
Sbjct: 1427 DLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKN 1486
Query: 203 SL-KSLEVSE--EKANQRVEE 220
+ +SLE E ++ N+ ++E
Sbjct: 1487 AYEESLEHLETFKRENKNLQE 1507
Score = 51.6 bits (118), Expect = 3e-06
Identities = 38/170 (22%), Positives = 83/170 (48%), Gaps = 7/170 (4%)
Query: 45 ELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 104
E +K++A ++E+ K LE++ +E E+++ + E L +VQ +++L +EE
Sbjct: 844 EREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 903
Query: 105 RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 164
R + ++ + E N R + +EE +LT + ++ + D+
Sbjct: 904 RCDQLIKNKIQLEAKVKEMNE-------RLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
+ LA VE E E++VK+ +++ L+E + + K+L+ + ++A
Sbjct: 957 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 1006
Score = 51.6 bits (118), Expect = 3e-06
Identities = 42/285 (14%), Positives = 120/285 (42%), Gaps = 1/285 (0%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D+++ + A ++ A+ E + ++ N E QK++ ++ L
Sbjct: 1594 VDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDT 1653
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L+ A + ++ ++ + E L +++++ +E++E A+Q+L+E +
Sbjct: 1654 QIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERV 1713
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L N+ ++ + + QL +++EA +A+ K+ + A + +EL+ +
Sbjct: 1714 QLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQ 1773
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + +E+ +K + + L E ++ + +++++
Sbjct: 1774 DTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRN 1833
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K ++ + L + ++ L D +D ++ Y
Sbjct: 1834 AESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1878
Score = 51.2 bits (117), Expect = 4e-06
Identities = 43/260 (16%), Positives = 102/260 (39%), Gaps = 10/260 (3%)
Query: 11 MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ E+DN D + C+Q + ++ N R E E EL K ++E++
Sbjct: 891 VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSEL 950
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K ++ L + EK+ ATE +V L ++ ++E + K + Q+ +A
Sbjct: 951 KRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDL 1010
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
L + E+++D L L++ + + D + ++ L ++ + E
Sbjct: 1011 QAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLE 1070
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+ + D ++ + + EL + ++ + + ++++E
Sbjct: 1071 NDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARA 1130
Query: 241 XXXKTVKKLQKEVDRLEDEL 260
K L +E++ + + L
Sbjct: 1131 KVEKLRSDLSRELEEISERL 1150
Score = 50.8 bits (116), Expect = 5e-06
Identities = 68/310 (21%), Positives = 135/310 (43%), Gaps = 33/310 (10%)
Query: 5 KKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI-LNK- 61
+++M A + +K D+ ++ D L KV +E + K+ + E++ L++
Sbjct: 929 EEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEI 988
Query: 62 -NKLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQQKL 113
KL + K L+E +Q L A E +V L + K++Q +DLE S E+ + L
Sbjct: 989 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 1048
Query: 114 LEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
A++ + + ++ + LEN QQ +ER+ + +L ED ++ +KL
Sbjct: 1049 ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKL 1108
Query: 170 AFVEDELEVAEDRV---KSGDAKI----SELEEELKVVGNSLK----SLEVSEEKANQRV 218
++ +E E+ + ++ AK+ S+L EL+ + L+ + V E +R
Sbjct: 1109 KELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKRE 1168
Query: 219 EEFXXXXXXXXXXXXXXXXXXXXXXK----TVKKLQKEVD---RLEDELGINKDRYKSLA 271
EF K +V +L +++D R++ +L K +K
Sbjct: 1169 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1228
Query: 272 DEMDSTFAEL 281
D++ S ++
Sbjct: 1229 DDVTSNMEQI 1238
Score = 44.0 bits (99), Expect = 6e-04
Identities = 29/184 (15%), Positives = 90/184 (48%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K++ ++ +LQ ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 1728 KKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1787
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LEN + +++R + ++++
Sbjct: 1788 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRI 1847
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + L ++D ++ + +VK+ + E EE+ + + ++ ++A
Sbjct: 1848 KELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAE 1907
Query: 216 QRVE 219
+R +
Sbjct: 1908 ERAD 1911
Score = 41.5 bits (93), Expect = 0.003
Identities = 49/227 (21%), Positives = 102/227 (44%), Gaps = 19/227 (8%)
Query: 12 KLEKDNAMDKADTCEQQAR-----DANLRAEKVNEEVRELQKKLAQVEEDL--------I 58
K E + KA++ Q R DA R E++ E ++L ++L + EE +
Sbjct: 1354 KAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSS 1413
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
L K K + ++E+ + + A AAL++K + ++ L + +++ +Q +L +Q+
Sbjct: 1414 LEKTK-HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQK 1472
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD---GKSDEVSRKLAFVEDE 175
A + L+N ++ E ++ + K + D G S + +L V +
Sbjct: 1473 EARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQ 1532
Query: 176 LEVAEDRVKSG--DAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
LE + ++S +A+ S EE K++ L+ ++ E + E+
Sbjct: 1533 LEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEK 1579
Score = 39.9 bits (89), Expect = 0.010
Identities = 35/166 (21%), Positives = 72/166 (43%), Gaps = 19/166 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTC-----EQQARDANLRAEKVNEEVRELQKKLAQVEE 55
++ +KK M+ + + +D+A+ ++Q + R ++ E+ QK+ A+ +
Sbjct: 1779 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVK 1838
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ ++ ++++ EE K L + V L KV+ + E++EE++ T K +
Sbjct: 1839 GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRK 1898
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
Q DE EER D +Q+ + R + D K
Sbjct: 1899 VQHELDEA--------------EERADIAESQVNKLRAKSRDIGTK 1930
Score = 31.5 bits (68), Expect = 3.5
Identities = 38/179 (21%), Positives = 78/179 (43%), Gaps = 10/179 (5%)
Query: 19 MDKADTCEQQARDANLRAEKVNEEVRE--LQKKLAQVEEDLILNKNKLEQANKDLEEKEK 76
M+K E Q +L + E L+KK A +L + L++ + LE+++
Sbjct: 1163 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1222
Query: 77 QLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ 136
+ + E+ + ++QI + E+ T + ++ E + A+E R L ++ +
Sbjct: 1223 EF---KLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAK 1279
Query: 137 DEERMDQLTNQLKEAR-LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 194
+ +L+ QL E L+++ GK + +ED E+ VK+ +A L+
Sbjct: 1280 LQTENGELSRQLDEKEALISQLTRGKLTYTQQ----LEDLKRQLEEEVKAKNALAHALQ 1334
>BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 62.1 bits (144), Expect = 2e-09
Identities = 47/206 (22%), Positives = 108/206 (52%), Gaps = 13/206 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKKM A ++ E + A+ + E++A+ A A + EE+++ Q A +E +
Sbjct: 1727 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 1783
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E +LE ++R+ + + + +
Sbjct: 1784 KN-MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRK 1842
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
+++ E + + ++ +D+L ++K + AE+A+ +++ K V+ E
Sbjct: 1843 SERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 1902
Query: 176 LEVAEDRVKSGDAKISELEEELKVVG 201
L+ AE+R ++++++L + + +G
Sbjct: 1903 LDEAEERADIAESQVNKLRAKSRDIG 1928
Score = 57.2 bits (132), Expect = 6e-08
Identities = 67/295 (22%), Positives = 126/295 (42%), Gaps = 26/295 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEK----VNEEVRELQKKLAQVE-- 54
+ +K+K++ K E +D + +Q A EK + +++ E + K + +
Sbjct: 1210 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRS 1269
Query: 55 -EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTA 109
DL + KL+ N +L +QL EA ++ L R QQ+ EDL++ E A
Sbjct: 1270 VNDLTSQRAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKA 1325
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGK 161
+ L A QSA + C +L + +++ E +L L +A +A+ DA +
Sbjct: 1326 KNALAHALQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQR 1382
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
++E+ + L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1383 TEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL 1442
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
++ QKE L EL K+ Y+ + +++
Sbjct: 1443 DKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1497
Score = 55.6 bits (128), Expect = 2e-07
Identities = 68/279 (24%), Positives = 130/279 (46%), Gaps = 25/279 (8%)
Query: 5 KKKMQAMKLE---KDNAMDKADTCEQQARD--ANLRAEK--VNEEVRELQKKLAQVEE-- 55
+K+M +MK E A++K++ ++ + +L EK + +V+ Q LA EE
Sbjct: 846 EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERC 905
Query: 56 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
LI NK +LE K++ E+ + AE+ A RK++ +L++ + K +
Sbjct: 906 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAK-V 964
Query: 115 EAQQSADENNRMCKVLENRAQQDE--ERMDQLTNQLKEARLLA-EDADGKSDEVSR---- 167
E ++ A E N++ + E A DE ++ + L+EA A +D + D+V+
Sbjct: 965 EKEKHATE-NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKA 1023
Query: 168 --KLAFVEDELEVAEDRVKSGDAKIS----ELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
KL D+LE + ++ K + +LE +LK+ S+ LE +++ ++R+++
Sbjct: 1024 KVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKK 1083
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
K +K+LQ ++ LE+EL
Sbjct: 1084 DFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1122
Score = 55.2 bits (127), Expect = 2e-07
Identities = 57/230 (24%), Positives = 114/230 (49%), Gaps = 23/230 (10%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 59
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1582
Query: 60 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 115
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1583 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 116 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 166
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
RKLA E EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 1699 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 1746
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 146 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 193
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 194 EEELKVVGNSLKSLEVSEEKANQ 216
+ E + +L+ + E N+
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLNE 1624
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/201 (22%), Positives = 87/201 (43%), Gaps = 4/201 (1%)
Query: 24 TCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 83
T QQ D + E+ + L L D L + + E+ + E ++ L+ +
Sbjct: 1307 TYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANS 1366
Query: 84 EVAALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 142
EVA K + + E+ EE Q+L EA+++ + N C LE + + ++
Sbjct: 1367 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE 1426
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 202
L ++ + A D K + LA + + E ++ ++S + L EL + N
Sbjct: 1427 DLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKN 1486
Query: 203 SL-KSLEVSE--EKANQRVEE 220
+ +SLE E ++ N+ ++E
Sbjct: 1487 AYEESLEHLETFKRENKNLQE 1507
Score = 51.6 bits (118), Expect = 3e-06
Identities = 38/170 (22%), Positives = 83/170 (48%), Gaps = 7/170 (4%)
Query: 45 ELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 104
E +K++A ++E+ K LE++ +E E+++ + E L +VQ +++L +EE
Sbjct: 844 EREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 903
Query: 105 RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 164
R + ++ + E N R + +EE +LT + ++ + D+
Sbjct: 904 RCDQLIKNKIQLEAKVKEMNE-------RLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
+ LA VE E E++VK+ +++ L+E + + K+L+ + ++A
Sbjct: 957 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 1006
Score = 51.6 bits (118), Expect = 3e-06
Identities = 42/285 (14%), Positives = 120/285 (42%), Gaps = 1/285 (0%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D+++ + A ++ A+ E + ++ N E QK++ ++ L
Sbjct: 1594 VDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDT 1653
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L+ A + ++ ++ + E L +++++ +E++E A+Q+L+E +
Sbjct: 1654 QIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERV 1713
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L N+ ++ + + QL +++EA +A+ K+ + A + +EL+ +
Sbjct: 1714 QLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQ 1773
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + +E+ +K + + L E ++ + +++++
Sbjct: 1774 DTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRN 1833
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K ++ + L + ++ L D +D ++ Y
Sbjct: 1834 AESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1878
Score = 51.2 bits (117), Expect = 4e-06
Identities = 43/260 (16%), Positives = 102/260 (39%), Gaps = 10/260 (3%)
Query: 11 MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ E+DN D + C+Q + ++ N R E E EL K ++E++
Sbjct: 891 VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSEL 950
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K ++ L + EK+ ATE +V L ++ ++E + K + Q+ +A
Sbjct: 951 KRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDL 1010
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
L + E+++D L L++ + + D + ++ L ++ + E
Sbjct: 1011 QAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLE 1070
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+ + D ++ + + EL + ++ + + ++++E
Sbjct: 1071 NDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARA 1130
Query: 241 XXXKTVKKLQKEVDRLEDEL 260
K L +E++ + + L
Sbjct: 1131 KVEKLRSDLSRELEEISERL 1150
Score = 50.8 bits (116), Expect = 5e-06
Identities = 68/310 (21%), Positives = 135/310 (43%), Gaps = 33/310 (10%)
Query: 5 KKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI-LNK- 61
+++M A + +K D+ ++ D L KV +E + K+ + E++ L++
Sbjct: 929 EEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEI 988
Query: 62 -NKLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQQKL 113
KL + K L+E +Q L A E +V L + K++Q +DLE S E+ + L
Sbjct: 989 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 1048
Query: 114 LEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
A++ + + ++ + LEN QQ +ER+ + +L ED ++ +KL
Sbjct: 1049 ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKL 1108
Query: 170 AFVEDELEVAEDRV---KSGDAKI----SELEEELKVVGNSLK----SLEVSEEKANQRV 218
++ +E E+ + ++ AK+ S+L EL+ + L+ + V E +R
Sbjct: 1109 KELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKRE 1168
Query: 219 EEFXXXXXXXXXXXXXXXXXXXXXXK----TVKKLQKEVD---RLEDELGINKDRYKSLA 271
EF K +V +L +++D R++ +L K +K
Sbjct: 1169 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1228
Query: 272 DEMDSTFAEL 281
D++ S ++
Sbjct: 1229 DDVTSNMEQI 1238
Score = 44.0 bits (99), Expect = 6e-04
Identities = 29/184 (15%), Positives = 90/184 (48%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K++ ++ +LQ ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 1728 KKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1787
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LEN + +++R + ++++
Sbjct: 1788 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRI 1847
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + L ++D ++ + +VK+ + E EE+ + + ++ ++A
Sbjct: 1848 KELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAE 1907
Query: 216 QRVE 219
+R +
Sbjct: 1908 ERAD 1911
Score = 41.5 bits (93), Expect = 0.003
Identities = 49/227 (21%), Positives = 102/227 (44%), Gaps = 19/227 (8%)
Query: 12 KLEKDNAMDKADTCEQQAR-----DANLRAEKVNEEVRELQKKLAQVEEDL--------I 58
K E + KA++ Q R DA R E++ E ++L ++L + EE +
Sbjct: 1354 KAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSS 1413
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
L K K + ++E+ + + A AAL++K + ++ L + +++ +Q +L +Q+
Sbjct: 1414 LEKTK-HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQK 1472
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD---GKSDEVSRKLAFVEDE 175
A + L+N ++ E ++ + K + D G S + +L V +
Sbjct: 1473 EARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQ 1532
Query: 176 LEVAEDRVKSG--DAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
LE + ++S +A+ S EE K++ L+ ++ E + E+
Sbjct: 1533 LEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEK 1579
Score = 39.9 bits (89), Expect = 0.010
Identities = 35/166 (21%), Positives = 72/166 (43%), Gaps = 19/166 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTC-----EQQARDANLRAEKVNEEVRELQKKLAQVEE 55
++ +KK M+ + + +D+A+ ++Q + R ++ E+ QK+ A+ +
Sbjct: 1779 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVK 1838
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ ++ ++++ EE K L + V L KV+ + E++EE++ T K +
Sbjct: 1839 GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRK 1898
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
Q DE EER D +Q+ + R + D K
Sbjct: 1899 VQHELDEA--------------EERADIAESQVNKLRAKSRDIGTK 1930
Score = 31.5 bits (68), Expect = 3.5
Identities = 38/179 (21%), Positives = 78/179 (43%), Gaps = 10/179 (5%)
Query: 19 MDKADTCEQQARDANLRAEKVNEEVRE--LQKKLAQVEEDLILNKNKLEQANKDLEEKEK 76
M+K E Q +L + E L+KK A +L + L++ + LE+++
Sbjct: 1163 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1222
Query: 77 QLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ 136
+ + E+ + ++QI + E+ T + ++ E + A+E R L ++ +
Sbjct: 1223 EF---KLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAK 1279
Query: 137 DEERMDQLTNQLKEAR-LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 194
+ +L+ QL E L+++ GK + +ED E+ VK+ +A L+
Sbjct: 1280 LQTENGELSRQLDEKEALISQLTRGKLTYTQQ----LEDLKRQLEEEVKAKNALAHALQ 1334
>AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antigen
MU-RMS-40.7B protein.
Length = 1179
Score = 62.1 bits (144), Expect = 2e-09
Identities = 47/206 (22%), Positives = 108/206 (52%), Gaps = 13/206 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKKM A ++ E + A+ + E++A+ A A + EE+++ Q A +E +
Sbjct: 971 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 1027
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E +LE ++R+ + + + +
Sbjct: 1028 KN-MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRK 1086
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
+++ E + + ++ +D+L ++K + AE+A+ +++ K V+ E
Sbjct: 1087 SERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 1146
Query: 176 LEVAEDRVKSGDAKISELEEELKVVG 201
L+ AE+R ++++++L + + +G
Sbjct: 1147 LDEAEERADIAESQVNKLRAKSRDIG 1172
Score = 56.8 bits (131), Expect = 8e-08
Identities = 67/295 (22%), Positives = 126/295 (42%), Gaps = 26/295 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEK----VNEEVRELQKKLAQVE-- 54
+ +K+K++ K E +D + +Q A EK + +++ E + K + +
Sbjct: 454 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRS 513
Query: 55 -EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTA 109
DL + KL+ N +L +QL EA ++ L R QQ+ EDL++ E A
Sbjct: 514 VNDLTSQQAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKA 569
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGK 161
+ L A QSA + C +L + +++ E +L L +A +A+ DA +
Sbjct: 570 KNALAHALQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQR 626
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
++E+ + L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 627 TEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL 686
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
++ QKE L EL K+ Y+ + +++
Sbjct: 687 DKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 741
Score = 55.6 bits (128), Expect = 2e-07
Identities = 68/279 (24%), Positives = 130/279 (46%), Gaps = 25/279 (8%)
Query: 5 KKKMQAMKLE---KDNAMDKADTCEQQARD--ANLRAEK--VNEEVRELQKKLAQVEE-- 55
+K+M +MK E A++K++ ++ + +L EK + +V+ Q LA EE
Sbjct: 90 EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERC 149
Query: 56 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
LI NK +LE K++ E+ + AE+ A RK++ +L++ + K +
Sbjct: 150 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAK-V 208
Query: 115 EAQQSADENNRMCKVLENRAQQDE--ERMDQLTNQLKEARLLA-EDADGKSDEVSR---- 167
E ++ A E N++ + E A DE ++ + L+EA A +D + D+V+
Sbjct: 209 EKEKHATE-NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKA 267
Query: 168 --KLAFVEDELEVAEDRVKSGDAKIS----ELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
KL D+LE + ++ K + +LE +LK+ S+ LE +++ ++R+++
Sbjct: 268 KVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKK 327
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
K +K+LQ ++ LE+EL
Sbjct: 328 DFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 366
Score = 55.2 bits (127), Expect = 2e-07
Identities = 57/230 (24%), Positives = 114/230 (49%), Gaps = 23/230 (10%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 59
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 770 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 826
Query: 60 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 115
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 827 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 882
Query: 116 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 166
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 883 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 942
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
RKLA E EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 943 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 990
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 666 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 725
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 726 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 785
Query: 146 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 193
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 786 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 845
Query: 194 EEELKVVGNSLKSLEVSEEKANQ 216
+ E + +L+ + E N+
Sbjct: 846 DAETRSRNEALRVKKKMEGDLNE 868
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/201 (22%), Positives = 87/201 (43%), Gaps = 4/201 (1%)
Query: 24 TCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 83
T QQ D + E+ + L L D L + + E+ + E ++ L+ +
Sbjct: 551 TYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANS 610
Query: 84 EVAALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 142
EVA K + + E+ EE Q+L EA+++ + N C LE + + ++
Sbjct: 611 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE 670
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 202
L ++ + A D K + LA + + E ++ ++S + L EL + N
Sbjct: 671 DLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKN 730
Query: 203 SL-KSLEVSE--EKANQRVEE 220
+ +SLE E ++ N+ ++E
Sbjct: 731 AYEESLEHLETFKRENKNLQE 751
Score = 51.6 bits (118), Expect = 3e-06
Identities = 38/170 (22%), Positives = 83/170 (48%), Gaps = 7/170 (4%)
Query: 45 ELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 104
E +K++A ++E+ K LE++ +E E+++ + E L +VQ +++L +EE
Sbjct: 88 EREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 147
Query: 105 RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 164
R + ++ + E N R + +EE +LT + ++ + D+
Sbjct: 148 RCDQLIKNKIQLEAKVKEMNE-------RLEDEEEMNAELTAKKRKLEDECSELKRDIDD 200
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
+ LA VE E E++VK+ +++ L+E + + K+L+ + ++A
Sbjct: 201 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 250
Score = 51.6 bits (118), Expect = 3e-06
Identities = 42/285 (14%), Positives = 120/285 (42%), Gaps = 1/285 (0%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D+++ + A ++ A+ E + ++ N E QK++ ++ L
Sbjct: 838 VDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDT 897
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L+ A + ++ ++ + E L +++++ +E++E A+Q+L+E +
Sbjct: 898 QIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERV 957
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L N+ ++ + + QL +++EA +A+ K+ + A + +EL+ +
Sbjct: 958 QLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQ 1017
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + +E+ +K + + L E ++ + +++++
Sbjct: 1018 DTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRN 1077
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K ++ + L + ++ L D +D ++ Y
Sbjct: 1078 AESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1122
Score = 51.2 bits (117), Expect = 4e-06
Identities = 43/260 (16%), Positives = 102/260 (39%), Gaps = 10/260 (3%)
Query: 11 MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ E+DN D + C+Q + ++ N R E E EL K ++E++
Sbjct: 135 VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSEL 194
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K ++ L + EK+ ATE +V L ++ ++E + K + Q+ +A
Sbjct: 195 KRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDL 254
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
L + E+++D L L++ + + D + ++ L ++ + E
Sbjct: 255 QAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLE 314
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+ + D ++ + + EL + ++ + + ++++E
Sbjct: 315 NDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARA 374
Query: 241 XXXKTVKKLQKEVDRLEDEL 260
K L +E++ + + L
Sbjct: 375 KVEKLRSDLSRELEEISERL 394
Score = 50.8 bits (116), Expect = 5e-06
Identities = 68/310 (21%), Positives = 135/310 (43%), Gaps = 33/310 (10%)
Query: 5 KKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI-LNK- 61
+++M A + +K D+ ++ D L KV +E + K+ + E++ L++
Sbjct: 173 EEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEI 232
Query: 62 -NKLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQQKL 113
KL + K L+E +Q L A E +V L + K++Q +DLE S E+ + L
Sbjct: 233 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 292
Query: 114 LEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
A++ + + ++ + LEN QQ +ER+ + +L ED ++ +KL
Sbjct: 293 ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKL 352
Query: 170 AFVEDELEVAEDRV---KSGDAKI----SELEEELKVVGNSLK----SLEVSEEKANQRV 218
++ +E E+ + ++ AK+ S+L EL+ + L+ + V E +R
Sbjct: 353 KELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKRE 412
Query: 219 EEFXXXXXXXXXXXXXXXXXXXXXXK----TVKKLQKEVD---RLEDELGINKDRYKSLA 271
EF K +V +L +++D R++ +L K +K
Sbjct: 413 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 472
Query: 272 DEMDSTFAEL 281
D++ S ++
Sbjct: 473 DDVTSNMEQI 482
Score = 44.0 bits (99), Expect = 6e-04
Identities = 29/184 (15%), Positives = 90/184 (48%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K++ ++ +LQ ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 972 KKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1031
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LEN + +++R + ++++
Sbjct: 1032 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRI 1091
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + L ++D ++ + +VK+ + E EE+ + + ++ ++A
Sbjct: 1092 KELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAE 1151
Query: 216 QRVE 219
+R +
Sbjct: 1152 ERAD 1155
Score = 41.5 bits (93), Expect = 0.003
Identities = 49/227 (21%), Positives = 102/227 (44%), Gaps = 19/227 (8%)
Query: 12 KLEKDNAMDKADTCEQQAR-----DANLRAEKVNEEVRELQKKLAQVEEDL--------I 58
K E + KA++ Q R DA R E++ E ++L ++L + EE +
Sbjct: 598 KAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSS 657
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
L K K + ++E+ + + A AAL++K + ++ L + +++ +Q +L +Q+
Sbjct: 658 LEKTK-HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQK 716
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD---GKSDEVSRKLAFVEDE 175
A + L+N ++ E ++ + K + D G S + +L V +
Sbjct: 717 EARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQ 776
Query: 176 LEVAEDRVKSG--DAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
LE + ++S +A+ S EE K++ L+ ++ E + E+
Sbjct: 777 LEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEK 823
Score = 39.9 bits (89), Expect = 0.010
Identities = 35/166 (21%), Positives = 72/166 (43%), Gaps = 19/166 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTC-----EQQARDANLRAEKVNEEVRELQKKLAQVEE 55
++ +KK M+ + + +D+A+ ++Q + R ++ E+ QK+ A+ +
Sbjct: 1023 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVK 1082
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ ++ ++++ EE K L + V L KV+ + E++EE++ T K +
Sbjct: 1083 GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRK 1142
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
Q DE EER D +Q+ + R + D K
Sbjct: 1143 VQHELDEA--------------EERADIAESQVNKLRAKSRDIGTK 1174
Score = 31.5 bits (68), Expect = 3.5
Identities = 38/179 (21%), Positives = 78/179 (43%), Gaps = 10/179 (5%)
Query: 19 MDKADTCEQQARDANLRAEKVNEEVRE--LQKKLAQVEEDLILNKNKLEQANKDLEEKEK 76
M+K E Q +L + E L+KK A +L + L++ + LE+++
Sbjct: 407 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 466
Query: 77 QLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ 136
+ + E+ + ++QI + E+ T + ++ E + A+E R L ++ +
Sbjct: 467 EF---KLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQQAK 523
Query: 137 DEERMDQLTNQLKEAR-LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 194
+ +L+ QL E L+++ GK + +ED E+ VK+ +A L+
Sbjct: 524 LQTENGELSRQLDEKEALISQLTRGKLTYTQQ----LEDLKRQLEEEVKAKNALAHALQ 578
>AL450304-5|CAI14877.1| 1609|Homo sapiens laminin, gamma 1 (formerly
LAMB2) protein.
Length = 1609
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 6/172 (3%)
Query: 33 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 92
N + NE+ RE Q+ L D KNK +A + +K T+T+AE +V
Sbjct: 1395 NQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEV 1454
Query: 93 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
++ ++ ++ A+++L Q AD++ M + AQ+ E + N +
Sbjct: 1455 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 1514
Query: 153 LLAED---ADGKSDEVS-RKLAFVEDELEVAEDRVKSG--DAKISELEEELK 198
+ D G+ D V KL +E L A+D +K D K+S+LE E K
Sbjct: 1515 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAK 1566
Score = 45.2 bits (102), Expect = 3e-04
Identities = 41/178 (23%), Positives = 72/178 (40%), Gaps = 7/178 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++ M+ +LE N ++K T +Q A RA+ E KK D + N
Sbjct: 1310 LREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKK----GRDTLQEAND 1365
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ KD + + T AE A RK+ I + + ++ E++ AQQ L A A E
Sbjct: 1366 ILNNLKDFDRRVND-NKTAAEEAL--RKIPAINQTITEANEKTREAQQALGSAAADATEA 1422
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E A ++ + + D D + + + ++L E EL+ +D
Sbjct: 1423 KNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKRKQD 1480
Score = 39.1 bits (87), Expect = 0.017
Identities = 35/254 (13%), Positives = 91/254 (35%), Gaps = 1/254 (0%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE-DLILNKNKLE 65
+++ + + + A + + E+QA + A++ ++ E+ +AQ+ D +N+
Sbjct: 1228 EIEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLENEAN 1287
Query: 66 QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
+ E E+ + + L ++ E +++ E+ T QQ + AD
Sbjct: 1288 NIKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKA 1347
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
+ + + + + + + N LK+ D ++E RK+ + + A ++ +
Sbjct: 1348 LAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAINQTITEANEKTRE 1407
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKT 245
+ + N E + K
Sbjct: 1408 AQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQ 1467
Query: 246 VKKLQKEVDRLEDE 259
+++ +KE+ R +D+
Sbjct: 1468 LQEAEKELKRKQDD 1481
Score = 37.5 bits (83), Expect = 0.053
Identities = 29/141 (20%), Positives = 57/141 (40%), Gaps = 4/141 (2%)
Query: 20 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 79
D+ E++ D A+ V + + L +L +V L ++L+ +EE
Sbjct: 1073 DRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAE 1132
Query: 80 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR--AQQD 137
A V R ++ +LEK+ + A + + + + D NN E R A++
Sbjct: 1133 QARAHVENTERLIEIASRELEKA--KVAAANVSVTQPESTGDPNNMTLLAEEARKLAERH 1190
Query: 138 EERMDQLTNQLKEARLLAEDA 158
++ D + K A + +A
Sbjct: 1191 KQEADDIVRVAKTANDTSTEA 1211
Score = 37.5 bits (83), Expect = 0.053
Identities = 45/207 (21%), Positives = 91/207 (43%), Gaps = 17/207 (8%)
Query: 31 DANL--RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEK--QLTATE---A 83
D NL R ++VN + +L + + N EQA +E E+ ++ + E A
Sbjct: 1096 DQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAEQARAHVENTERLIEIASRELEKA 1155
Query: 84 EVAALNRKVQQIEEDLEKSE-ERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERM 141
+VAA N V Q E + + +KL E +Q AD+ R+ K + + + +
Sbjct: 1156 KVAAANVSVTQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLL 1215
Query: 142 -------DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 194
+Q +++E E A S ++ ++ A V +E + A D+ A +++L
Sbjct: 1216 LRTLAGENQTAFEIEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLS 1275
Query: 195 E-ELKVVGNSLKSLEVSEEKANQRVEE 220
+ + + N ++++ E Q +++
Sbjct: 1276 PLDSETLENEANNIKMEAENLEQLIDQ 1302
Score = 32.3 bits (70), Expect = 2.0
Identities = 41/216 (18%), Positives = 82/216 (37%), Gaps = 13/216 (6%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D + + A K + A K Q+A D + + V + + + +
Sbjct: 1336 DQLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAIN 1395
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT-----AQQKLLEA 116
+ +AN+ E ++ L + A+ K + E + + +++ T A++ E
Sbjct: 1396 QTITEANEKTREAQQALGSAAADATEAKNKAHEAER-IASAVQKNATSTKAEAERTFAEV 1454
Query: 117 QQSADENNRMCKVLE------NRAQQDEERMDQLTNQLKEARLLAE-DADGKSDEVSRKL 169
+E N M K L+ R Q D ++ + +A AE +A + V+ L
Sbjct: 1455 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 1514
Query: 170 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
+ + D LE K++E+E L + +K
Sbjct: 1515 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMK 1550
>AL354953-3|CAH70981.1| 1609|Homo sapiens laminin, gamma 1 (formerly
LAMB2) protein.
Length = 1609
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 6/172 (3%)
Query: 33 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 92
N + NE+ RE Q+ L D KNK +A + +K T+T+AE +V
Sbjct: 1395 NQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEV 1454
Query: 93 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
++ ++ ++ A+++L Q AD++ M + AQ+ E + N +
Sbjct: 1455 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 1514
Query: 153 LLAED---ADGKSDEVS-RKLAFVEDELEVAEDRVKSG--DAKISELEEELK 198
+ D G+ D V KL +E L A+D +K D K+S+LE E K
Sbjct: 1515 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAK 1566
Score = 45.2 bits (102), Expect = 3e-04
Identities = 41/178 (23%), Positives = 72/178 (40%), Gaps = 7/178 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++ M+ +LE N ++K T +Q A RA+ E KK D + N
Sbjct: 1310 LREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKK----GRDTLQEAND 1365
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ KD + + T AE A RK+ I + + ++ E++ AQQ L A A E
Sbjct: 1366 ILNNLKDFDRRVND-NKTAAEEAL--RKIPAINQTITEANEKTREAQQALGSAAADATEA 1422
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E A ++ + + D D + + + ++L E EL+ +D
Sbjct: 1423 KNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKRKQD 1480
Score = 39.1 bits (87), Expect = 0.017
Identities = 35/254 (13%), Positives = 91/254 (35%), Gaps = 1/254 (0%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE-DLILNKNKLE 65
+++ + + + A + + E+QA + A++ ++ E+ +AQ+ D +N+
Sbjct: 1228 EIEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLENEAN 1287
Query: 66 QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
+ E E+ + + L ++ E +++ E+ T QQ + AD
Sbjct: 1288 NIKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKA 1347
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
+ + + + + + + N LK+ D ++E RK+ + + A ++ +
Sbjct: 1348 LAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAINQTITEANEKTRE 1407
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKT 245
+ + N E + K
Sbjct: 1408 AQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQ 1467
Query: 246 VKKLQKEVDRLEDE 259
+++ +KE+ R +D+
Sbjct: 1468 LQEAEKELKRKQDD 1481
Score = 37.5 bits (83), Expect = 0.053
Identities = 29/141 (20%), Positives = 57/141 (40%), Gaps = 4/141 (2%)
Query: 20 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 79
D+ E++ D A+ V + + L +L +V L ++L+ +EE
Sbjct: 1073 DRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAE 1132
Query: 80 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR--AQQD 137
A V R ++ +LEK+ + A + + + + D NN E R A++
Sbjct: 1133 QARAHVENTERLIEIASRELEKA--KVAAANVSVTQPESTGDPNNMTLLAEEARKLAERH 1190
Query: 138 EERMDQLTNQLKEARLLAEDA 158
++ D + K A + +A
Sbjct: 1191 KQEADDIVRVAKTANDTSTEA 1211
Score = 37.5 bits (83), Expect = 0.053
Identities = 45/207 (21%), Positives = 91/207 (43%), Gaps = 17/207 (8%)
Query: 31 DANL--RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEK--QLTATE---A 83
D NL R ++VN + +L + + N EQA +E E+ ++ + E A
Sbjct: 1096 DQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAEQARAHVENTERLIEIASRELEKA 1155
Query: 84 EVAALNRKVQQIEEDLEKSE-ERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERM 141
+VAA N V Q E + + +KL E +Q AD+ R+ K + + + +
Sbjct: 1156 KVAAANVSVTQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLL 1215
Query: 142 -------DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 194
+Q +++E E A S ++ ++ A V +E + A D+ A +++L
Sbjct: 1216 LRTLAGENQTAFEIEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLS 1275
Query: 195 E-ELKVVGNSLKSLEVSEEKANQRVEE 220
+ + + N ++++ E Q +++
Sbjct: 1276 PLDSETLENEANNIKMEAENLEQLIDQ 1302
Score = 32.3 bits (70), Expect = 2.0
Identities = 41/216 (18%), Positives = 82/216 (37%), Gaps = 13/216 (6%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D + + A K + A K Q+A D + + V + + + +
Sbjct: 1336 DQLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAIN 1395
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT-----AQQKLLEA 116
+ +AN+ E ++ L + A+ K + E + + +++ T A++ E
Sbjct: 1396 QTITEANEKTREAQQALGSAAADATEAKNKAHEAER-IASAVQKNATSTKAEAERTFAEV 1454
Query: 117 QQSADENNRMCKVLE------NRAQQDEERMDQLTNQLKEARLLAE-DADGKSDEVSRKL 169
+E N M K L+ R Q D ++ + +A AE +A + V+ L
Sbjct: 1455 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 1514
Query: 170 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
+ + D LE K++E+E L + +K
Sbjct: 1515 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMK 1550
>AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 62.1 bits (144), Expect = 2e-09
Identities = 47/206 (22%), Positives = 108/206 (52%), Gaps = 13/206 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKKM A ++ E + A+ + E++A+ A A + EE+++ Q A +E +
Sbjct: 1727 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 1783
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E +LE ++R+ + + + +
Sbjct: 1784 KN-MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRK 1842
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
+++ E + + ++ +D+L ++K + AE+A+ +++ K V+ E
Sbjct: 1843 SERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 1902
Query: 176 LEVAEDRVKSGDAKISELEEELKVVG 201
L+ AE+R ++++++L + + +G
Sbjct: 1903 LDEAEERADIAESQVNKLRAKSRDIG 1928
Score = 57.2 bits (132), Expect = 6e-08
Identities = 67/295 (22%), Positives = 126/295 (42%), Gaps = 26/295 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEK----VNEEVRELQKKLAQVE-- 54
+ +K+K++ K E +D + +Q A EK + +++ E + K + +
Sbjct: 1210 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRS 1269
Query: 55 -EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTA 109
DL + KL+ N +L +QL EA ++ L R QQ+ EDL++ E A
Sbjct: 1270 VNDLTSQRAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKA 1325
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGK 161
+ L A QSA + C +L + +++ E +L L +A +A+ DA +
Sbjct: 1326 KNALAHALQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQR 1382
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
++E+ + L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1383 TEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL 1442
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
++ QKE L EL K+ Y+ + +++
Sbjct: 1443 DKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1497
Score = 55.6 bits (128), Expect = 2e-07
Identities = 68/279 (24%), Positives = 130/279 (46%), Gaps = 25/279 (8%)
Query: 5 KKKMQAMKLE---KDNAMDKADTCEQQARD--ANLRAEK--VNEEVRELQKKLAQVEE-- 55
+K+M +MK E A++K++ ++ + +L EK + +V+ Q LA EE
Sbjct: 846 EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERC 905
Query: 56 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
LI NK +LE K++ E+ + AE+ A RK++ +L++ + K +
Sbjct: 906 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAK-V 964
Query: 115 EAQQSADENNRMCKVLENRAQQDE--ERMDQLTNQLKEARLLA-EDADGKSDEVSR---- 167
E ++ A E N++ + E A DE ++ + L+EA A +D + D+V+
Sbjct: 965 EKEKHATE-NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKA 1023
Query: 168 --KLAFVEDELEVAEDRVKSGDAKIS----ELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
KL D+LE + ++ K + +LE +LK+ S+ LE +++ ++R+++
Sbjct: 1024 KVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKK 1083
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
K +K+LQ ++ LE+EL
Sbjct: 1084 DFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1122
Score = 55.2 bits (127), Expect = 2e-07
Identities = 57/230 (24%), Positives = 114/230 (49%), Gaps = 23/230 (10%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 59
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1582
Query: 60 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 115
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1583 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 116 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 166
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
RKLA E EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 1699 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 1746
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 146 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 193
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 194 EEELKVVGNSLKSLEVSEEKANQ 216
+ E + +L+ + E N+
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLNE 1624
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/201 (22%), Positives = 87/201 (43%), Gaps = 4/201 (1%)
Query: 24 TCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 83
T QQ D + E+ + L L D L + + E+ + E ++ L+ +
Sbjct: 1307 TYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANS 1366
Query: 84 EVAALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 142
EVA K + + E+ EE Q+L EA+++ + N C LE + + ++
Sbjct: 1367 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE 1426
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 202
L ++ + A D K + LA + + E ++ ++S + L EL + N
Sbjct: 1427 DLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKN 1486
Query: 203 SL-KSLEVSE--EKANQRVEE 220
+ +SLE E ++ N+ ++E
Sbjct: 1487 AYEESLEHLETFKRENKNLQE 1507
Score = 51.6 bits (118), Expect = 3e-06
Identities = 38/170 (22%), Positives = 83/170 (48%), Gaps = 7/170 (4%)
Query: 45 ELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 104
E +K++A ++E+ K LE++ +E E+++ + E L +VQ +++L +EE
Sbjct: 844 EREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 903
Query: 105 RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 164
R + ++ + E N R + +EE +LT + ++ + D+
Sbjct: 904 RCDQLIKNKIQLEAKVKEMNE-------RLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
+ LA VE E E++VK+ +++ L+E + + K+L+ + ++A
Sbjct: 957 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 1006
Score = 51.6 bits (118), Expect = 3e-06
Identities = 42/285 (14%), Positives = 120/285 (42%), Gaps = 1/285 (0%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D+++ + A ++ A+ E + ++ N E QK++ ++ L
Sbjct: 1594 VDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDT 1653
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L+ A + ++ ++ + E L +++++ +E++E A+Q+L+E +
Sbjct: 1654 QIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERV 1713
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L N+ ++ + + QL +++EA +A+ K+ + A + +EL+ +
Sbjct: 1714 QLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQ 1773
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + +E+ +K + + L E ++ + +++++
Sbjct: 1774 DTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRN 1833
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K ++ + L + ++ L D +D ++ Y
Sbjct: 1834 AESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1878
Score = 51.2 bits (117), Expect = 4e-06
Identities = 43/260 (16%), Positives = 102/260 (39%), Gaps = 10/260 (3%)
Query: 11 MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ E+DN D + C+Q + ++ N R E E EL K ++E++
Sbjct: 891 VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSEL 950
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K ++ L + EK+ ATE +V L ++ ++E + K + Q+ +A
Sbjct: 951 KRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDL 1010
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
L + E+++D L L++ + + D + ++ L ++ + E
Sbjct: 1011 QAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLE 1070
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+ + D ++ + + EL + ++ + + ++++E
Sbjct: 1071 NDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARA 1130
Query: 241 XXXKTVKKLQKEVDRLEDEL 260
K L +E++ + + L
Sbjct: 1131 KVEKLRSDLSRELEEISERL 1150
Score = 49.6 bits (113), Expect = 1e-05
Identities = 50/211 (23%), Positives = 100/211 (47%), Gaps = 18/211 (8%)
Query: 5 KKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI-LNK- 61
+++M A + +K D+ ++ D L KV +E + K+ + E++ L++
Sbjct: 929 EEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEI 988
Query: 62 -NKLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQQKL 113
KL + K L+E +Q L A E +V L + K++Q +DLE S E+ + L
Sbjct: 989 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 1048
Query: 114 LEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
A++ + + ++ + LEN QQ +ER+ + +L ED ++ +KL
Sbjct: 1049 ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKL 1108
Query: 170 AFVEDELEVAEDRV---KSGDAKISELEEEL 197
++ +E E+ + ++ AK+ +L +L
Sbjct: 1109 KELQARIEELEEELEAERTARAKVEKLRSDL 1139
Score = 46.4 bits (105), Expect = 1e-04
Identities = 33/153 (21%), Positives = 72/153 (47%), Gaps = 3/153 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1004 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 1061 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 1120
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+L+ R + ++SR+L + + LE A
Sbjct: 1121 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 1153
Score = 45.6 bits (103), Expect = 2e-04
Identities = 56/293 (19%), Positives = 127/293 (43%), Gaps = 20/293 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++ + ++ EK +K ++ + K+ +E + LQ+ Q +DL
Sbjct: 954 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE 1013
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
++K+ K + E+Q+ E + + +++ DLE++ +R KL +
Sbjct: 1014 EDKVNTLTKAKVKLEQQVDDLEGSL----EQEKKVRMDLERA-KRKLEGDLKLTQESIMD 1068
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
EN++ + L+ R ++ + ++ L ++++ + L K E+ ++ +E+ELE AE
Sbjct: 1069 LENDK--QQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELE-AE 1125
Query: 181 DRVKSGDAKI-SELEEELKVVGNSLK----SLEVSEEKANQRVEEFXXXXXXXXXXXXXX 235
++ K+ S+L EL+ + L+ + E +R EF
Sbjct: 1126 RTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKREAEFQKMRRDLEEATLQH 1185
Query: 236 XXXXXXXXK----TVKKLQKEVD---RLEDELGINKDRYKSLADEMDSTFAEL 281
K +V +L +++D R++ +L K +K D++ S ++
Sbjct: 1186 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQI 1238
Score = 44.0 bits (99), Expect = 6e-04
Identities = 29/184 (15%), Positives = 90/184 (48%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K++ ++ +LQ ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 1728 KKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1787
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LEN + +++R + ++++
Sbjct: 1788 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRI 1847
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + L ++D ++ + +VK+ + E EE+ + + ++ ++A
Sbjct: 1848 KELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAE 1907
Query: 216 QRVE 219
+R +
Sbjct: 1908 ERAD 1911
Score = 41.5 bits (93), Expect = 0.003
Identities = 49/227 (21%), Positives = 102/227 (44%), Gaps = 19/227 (8%)
Query: 12 KLEKDNAMDKADTCEQQAR-----DANLRAEKVNEEVRELQKKLAQVEEDL--------I 58
K E + KA++ Q R DA R E++ E ++L ++L + EE +
Sbjct: 1354 KAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSS 1413
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
L K K + ++E+ + + A AAL++K + ++ L + +++ +Q +L +Q+
Sbjct: 1414 LEKTK-HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQK 1472
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD---GKSDEVSRKLAFVEDE 175
A + L+N ++ E ++ + K + D G S + +L V +
Sbjct: 1473 EARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQ 1532
Query: 176 LEVAEDRVKSG--DAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
LE + ++S +A+ S EE K++ L+ ++ E + E+
Sbjct: 1533 LEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEK 1579
Score = 39.9 bits (89), Expect = 0.010
Identities = 35/166 (21%), Positives = 72/166 (43%), Gaps = 19/166 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTC-----EQQARDANLRAEKVNEEVRELQKKLAQVEE 55
++ +KK M+ + + +D+A+ ++Q + R ++ E+ QK+ A+ +
Sbjct: 1779 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVK 1838
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ ++ ++++ EE K L + V L KV+ + E++EE++ T K +
Sbjct: 1839 GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRK 1898
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
Q DE EER D +Q+ + R + D K
Sbjct: 1899 VQHELDEA--------------EERADIAESQVNKLRAKSRDIGTK 1930
Score = 31.5 bits (68), Expect = 3.5
Identities = 38/179 (21%), Positives = 78/179 (43%), Gaps = 10/179 (5%)
Query: 19 MDKADTCEQQARDANLRAEKVNEEVRE--LQKKLAQVEEDLILNKNKLEQANKDLEEKEK 76
M+K E Q +L + E L+KK A +L + L++ + LE+++
Sbjct: 1163 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1222
Query: 77 QLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ 136
+ + E+ + ++QI + E+ T + ++ E + A+E R L ++ +
Sbjct: 1223 EF---KLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAK 1279
Query: 137 DEERMDQLTNQLKEAR-LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 194
+ +L+ QL E L+++ GK + +ED E+ VK+ +A L+
Sbjct: 1280 LQTENGELSRQLDEKEALISQLTRGKLTYTQQ----LEDLKRQLEEEVKAKNALAHALQ 1334
>AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypeptide 7,
cardiac muscle, beta variant protein.
Length = 1574
Score = 62.1 bits (144), Expect = 2e-09
Identities = 47/206 (22%), Positives = 108/206 (52%), Gaps = 13/206 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKKM A ++ E + A+ + E++A+ A A + EE+++ Q A +E +
Sbjct: 1366 KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 1422
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E +LE ++R+ + + + +
Sbjct: 1423 KN-MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRK 1481
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
+++ E + + ++ +D+L ++K + AE+A+ +++ K V+ E
Sbjct: 1482 SERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 1541
Query: 176 LEVAEDRVKSGDAKISELEEELKVVG 201
L+ AE+R ++++++L + + +G
Sbjct: 1542 LDEAEERADIAESQVNKLRAKSRDIG 1567
Score = 57.2 bits (132), Expect = 6e-08
Identities = 67/295 (22%), Positives = 126/295 (42%), Gaps = 26/295 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEK----VNEEVRELQKKLAQVE-- 54
+ +K+K++ K E +D + +Q A EK + +++ E + K + +
Sbjct: 849 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRS 908
Query: 55 -EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTA 109
DL + KL+ N +L +QL EA ++ L R QQ+ EDL++ E A
Sbjct: 909 VNDLTSQRAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKA 964
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGK 161
+ L A QSA + C +L + +++ E +L L +A +A+ DA +
Sbjct: 965 KNALAHALQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQR 1021
Query: 162 SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
++E+ + L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1022 TEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL 1081
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
++ QKE L EL K+ Y+ + +++
Sbjct: 1082 DKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1136
Score = 55.6 bits (128), Expect = 2e-07
Identities = 68/279 (24%), Positives = 130/279 (46%), Gaps = 25/279 (8%)
Query: 5 KKKMQAMKLE---KDNAMDKADTCEQQARD--ANLRAEK--VNEEVRELQKKLAQVEE-- 55
+K+M +MK E A++K++ ++ + +L EK + +V+ Q LA EE
Sbjct: 485 EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERC 544
Query: 56 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
LI NK +LE K++ E+ + AE+ A RK++ +L++ + K +
Sbjct: 545 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAK-V 603
Query: 115 EAQQSADENNRMCKVLENRAQQDE--ERMDQLTNQLKEARLLA-EDADGKSDEVSR---- 167
E ++ A E N++ + E A DE ++ + L+EA A +D + D+V+
Sbjct: 604 EKEKHATE-NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKA 662
Query: 168 --KLAFVEDELEVAEDRVKSGDAKIS----ELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
KL D+LE + ++ K + +LE +LK+ S+ LE +++ ++R+++
Sbjct: 663 KVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKK 722
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
K +K+LQ ++ LE+EL
Sbjct: 723 DFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 761
Score = 55.2 bits (127), Expect = 2e-07
Identities = 57/230 (24%), Positives = 114/230 (49%), Gaps = 23/230 (10%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 59
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1165 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1221
Query: 60 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 115
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1222 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1277
Query: 116 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 166
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1278 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1337
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
RKLA E EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 1338 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 1385
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/203 (21%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1061 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1120
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1121 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1180
Query: 146 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISEL 193
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1181 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1240
Query: 194 EEELKVVGNSLKSLEVSEEKANQ 216
+ E + +L+ + E N+
Sbjct: 1241 DAETRSRNEALRVKKKMEGDLNE 1263
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/201 (22%), Positives = 87/201 (43%), Gaps = 4/201 (1%)
Query: 24 TCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 83
T QQ D + E+ + L L D L + + E+ + E ++ L+ +
Sbjct: 946 TYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANS 1005
Query: 84 EVAALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 142
EVA K + + E+ EE Q+L EA+++ + N C LE + + ++
Sbjct: 1006 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE 1065
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 202
L ++ + A D K + LA + + E ++ ++S + L EL + N
Sbjct: 1066 DLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKN 1125
Query: 203 SL-KSLEVSE--EKANQRVEE 220
+ +SLE E ++ N+ ++E
Sbjct: 1126 AYEESLEHLETFKRENKNLQE 1146
Score = 51.6 bits (118), Expect = 3e-06
Identities = 38/170 (22%), Positives = 83/170 (48%), Gaps = 7/170 (4%)
Query: 45 ELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 104
E +K++A ++E+ K LE++ +E E+++ + E L +VQ +++L +EE
Sbjct: 483 EREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 542
Query: 105 RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 164
R + ++ + E N R + +EE +LT + ++ + D+
Sbjct: 543 RCDQLIKNKIQLEAKVKEMNE-------RLEDEEEMNAELTAKKRKLEDECSELKRDIDD 595
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
+ LA VE E E++VK+ +++ L+E + + K+L+ + ++A
Sbjct: 596 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 645
Score = 51.6 bits (118), Expect = 3e-06
Identities = 42/285 (14%), Positives = 120/285 (42%), Gaps = 1/285 (0%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D+++ + A ++ A+ E + ++ N E QK++ ++ L
Sbjct: 1233 VDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDT 1292
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L+ A + ++ ++ + E L +++++ +E++E A+Q+L+E +
Sbjct: 1293 QIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERV 1352
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L N+ ++ + + QL +++EA +A+ K+ + A + +EL+ +
Sbjct: 1353 QLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQ 1412
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + +E+ +K + + L E ++ + +++++
Sbjct: 1413 DTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRN 1472
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K ++ + L + ++ L D +D ++ Y
Sbjct: 1473 AESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1517
Score = 51.2 bits (117), Expect = 4e-06
Identities = 43/260 (16%), Positives = 102/260 (39%), Gaps = 10/260 (3%)
Query: 11 MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ E+DN D + C+Q + ++ N R E E EL K ++E++
Sbjct: 530 VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSEL 589
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K ++ L + EK+ ATE +V L ++ ++E + K + Q+ +A
Sbjct: 590 KRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDL 649
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
L + E+++D L L++ + + D + ++ L ++ + E
Sbjct: 650 QAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLE 709
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+ + D ++ + + EL + ++ + + ++++E
Sbjct: 710 NDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARA 769
Query: 241 XXXKTVKKLQKEVDRLEDEL 260
K L +E++ + + L
Sbjct: 770 KVEKLRSDLSRELEEISERL 789
Score = 50.8 bits (116), Expect = 5e-06
Identities = 68/310 (21%), Positives = 135/310 (43%), Gaps = 33/310 (10%)
Query: 5 KKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI-LNK- 61
+++M A + +K D+ ++ D L KV +E + K+ + E++ L++
Sbjct: 568 EEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEI 627
Query: 62 -NKLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQQKL 113
KL + K L+E +Q L A E +V L + K++Q +DLE S E+ + L
Sbjct: 628 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 687
Query: 114 LEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
A++ + + ++ + LEN QQ +ER+ + +L ED ++ +KL
Sbjct: 688 ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKL 747
Query: 170 AFVEDELEVAEDRV---KSGDAKI----SELEEELKVVGNSLK----SLEVSEEKANQRV 218
++ +E E+ + ++ AK+ S+L EL+ + L+ + V E +R
Sbjct: 748 KELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKRE 807
Query: 219 EEFXXXXXXXXXXXXXXXXXXXXXXK----TVKKLQKEVD---RLEDELGINKDRYKSLA 271
EF K +V +L +++D R++ +L K +K
Sbjct: 808 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 867
Query: 272 DEMDSTFAEL 281
D++ S ++
Sbjct: 868 DDVTSNMEQI 877
Score = 44.0 bits (99), Expect = 6e-04
Identities = 29/184 (15%), Positives = 90/184 (48%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K++ ++ +LQ ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 1367 KKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1426
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LEN + +++R + ++++
Sbjct: 1427 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRI 1486
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + L ++D ++ + +VK+ + E EE+ + + ++ ++A
Sbjct: 1487 KELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAE 1546
Query: 216 QRVE 219
+R +
Sbjct: 1547 ERAD 1550
Score = 41.5 bits (93), Expect = 0.003
Identities = 49/227 (21%), Positives = 102/227 (44%), Gaps = 19/227 (8%)
Query: 12 KLEKDNAMDKADTCEQQAR-----DANLRAEKVNEEVRELQKKLAQVEEDL--------I 58
K E + KA++ Q R DA R E++ E ++L ++L + EE +
Sbjct: 993 KAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSS 1052
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
L K K + ++E+ + + A AAL++K + ++ L + +++ +Q +L +Q+
Sbjct: 1053 LEKTK-HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQK 1111
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD---GKSDEVSRKLAFVEDE 175
A + L+N ++ E ++ + K + D G S + +L V +
Sbjct: 1112 EARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQ 1171
Query: 176 LEVAEDRVKSG--DAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
LE + ++S +A+ S EE K++ L+ ++ E + E+
Sbjct: 1172 LEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEK 1218
Score = 39.9 bits (89), Expect = 0.010
Identities = 35/166 (21%), Positives = 72/166 (43%), Gaps = 19/166 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTC-----EQQARDANLRAEKVNEEVRELQKKLAQVEE 55
++ +KK M+ + + +D+A+ ++Q + R ++ E+ QK+ A+ +
Sbjct: 1418 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVK 1477
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ ++ ++++ EE K L + V L KV+ + E++EE++ T K +
Sbjct: 1478 GMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRK 1537
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
Q DE EER D +Q+ + R + D K
Sbjct: 1538 VQHELDEA--------------EERADIAESQVNKLRAKSRDIGTK 1569
Score = 31.5 bits (68), Expect = 3.5
Identities = 38/179 (21%), Positives = 78/179 (43%), Gaps = 10/179 (5%)
Query: 19 MDKADTCEQQARDANLRAEKVNEEVRE--LQKKLAQVEEDLILNKNKLEQANKDLEEKEK 76
M+K E Q +L + E L+KK A +L + L++ + LE+++
Sbjct: 802 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 861
Query: 77 QLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ 136
+ + E+ + ++QI + E+ T + ++ E + A+E R L ++ +
Sbjct: 862 EF---KLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAK 918
Query: 137 DEERMDQLTNQLKEAR-LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 194
+ +L+ QL E L+++ GK + +ED E+ VK+ +A L+
Sbjct: 919 LQTENGELSRQLDEKEALISQLTRGKLTYTQQ----LEDLKRQLEEEVKAKNALAHALQ 973
>Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein.
Length = 1937
Score = 61.7 bits (143), Expect = 3e-09
Identities = 60/277 (21%), Positives = 125/277 (45%), Gaps = 18/277 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++K+ +K+E D+ A+ + + + ++V EL+ K + E+ ++N
Sbjct: 1220 LEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTK--EEEQQRLINDLT 1277
Query: 64 LEQANKDLE--EKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQQKLLEAQ 117
++A E E +QL +A V+ L+R QQIEE + EE + A+ L A
Sbjct: 1278 AQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEET-KAKNALAHAL 1336
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
QS+ + C +L + ++++E +L L +A +E A ++ + + E ELE
Sbjct: 1337 QSSRHD---CDLLREQYEEEQEGKAELQRALSKAN--SEVAQWRTKYETDAIQRTE-ELE 1390
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXX 237
A+ ++ ++ E EE ++ V SLE ++++ VE+
Sbjct: 1391 EAKKKLAQ---RLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDK 1447
Query: 238 XXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
K + + +++ + + EL ++ +SL+ E+
Sbjct: 1448 KQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTEL 1484
Score = 60.9 bits (141), Expect = 5e-09
Identities = 44/208 (21%), Positives = 106/208 (50%), Gaps = 9/208 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ + ++ E + + ++ E++A+ A A + EE+++ Q A +E + KN
Sbjct: 1733 LENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MKKN- 1788
Query: 64 LEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
LEQ KDL E ++ L + ++ L +V+++E ++E ++R+ A + L + ++
Sbjct: 1789 LEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHER 1848
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
E + + ++ +D+L ++K + AE+A+ +S+ K ++ ELE
Sbjct: 1849 RVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEE 1908
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKS 206
AE+R ++++++L + + V + +
Sbjct: 1909 AEERAHIAESQVNKLRVKSREVHTKISA 1936
Score = 56.0 bits (129), Expect = 1e-07
Identities = 54/262 (20%), Positives = 114/262 (43%), Gaps = 20/262 (7%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE----QANK 69
E D+ D + CEQ ++ ++ E +EV E ++ ++ +L K KLE + K
Sbjct: 897 EADSLADAEERCEQLIKN-KIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKK 955
Query: 70 DLEEKE-------KQLTATEAEVAALNRKVQQIEEDLEK-SEERSG---TAQQKLLEAQQ 118
D+++ E K+ ATE +V L ++ ++E + K S+E+ T QQ L + Q
Sbjct: 956 DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQA 1015
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
D+ N +L + E+++D L L++ + L D + ++ L ++
Sbjct: 1016 EEDKVN----ILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMD 1071
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXX 238
E+ + D K+ + E E+ + + ++ + E + ++++E
Sbjct: 1072 MENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERAS 1131
Query: 239 XXXXXKTVKKLQKEVDRLEDEL 260
K L +E++ + + L
Sbjct: 1132 RAKAEKQRSDLSRELEEISERL 1153
Score = 51.6 bits (118), Expect = 3e-06
Identities = 52/261 (19%), Positives = 113/261 (43%), Gaps = 15/261 (5%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++KM + EK++ + + DA R E++ + +L+ K+ +V E +
Sbjct: 876 LEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTE----RAEE 931
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK---LLEAQQSA 120
E+ N +L K+++L E E + L + + +E L K E+ + K L E
Sbjct: 932 EEEINAELTAKKRKL---EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 988
Query: 121 DEN-NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
DE ++ K + + ++ +D L + + +L + +V +E E ++
Sbjct: 989 DETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLR 1048
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + AK +LE +LK+ S +E +++ ++++E+
Sbjct: 1049 MDLER---AK-RKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVE 1104
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
K +K+LQ ++ L +E+
Sbjct: 1105 IQLQKKIKELQARIEELGEEI 1125
Score = 51.6 bits (118), Expect = 3e-06
Identities = 47/285 (16%), Positives = 118/285 (41%), Gaps = 1/285 (0%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ ++ + A +++A+ E + ++ N E + + L
Sbjct: 1597 VETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKET 1656
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ L+ A + E+ ++QL E L +++++ LE++E A+Q+LL+A +
Sbjct: 1657 QLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERV 1716
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L N ++ E + QL ++++E + +A+ K+ + A + +EL+ +
Sbjct: 1717 QLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQ 1776
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + LE+ +K + + L E ++ + +++++
Sbjct: 1777 DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRN 1836
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K ++ V L + ++ L D +D A++ Y
Sbjct: 1837 AEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSY 1881
Score = 49.2 bits (112), Expect = 2e-05
Identities = 29/165 (17%), Positives = 80/165 (48%)
Query: 49 KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 108
K A+ E+++ K + ++ +L + E + E ++ L ++ ++ ++ +
Sbjct: 844 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 903
Query: 109 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
A+++ + ++ + K + RA+++EE +LT + ++ + D++
Sbjct: 904 AEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELT 963
Query: 169 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
LA VE E E++VK+ +++ L+E + + K+L+ + ++
Sbjct: 964 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQ 1008
Score = 47.6 bits (108), Expect = 5e-05
Identities = 33/182 (18%), Positives = 87/182 (47%), Gaps = 1/182 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K+ +V +LQ ++ +V ++ + K ++A D ++L + A L R + +E
Sbjct: 1731 KKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLE 1790
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LE + +++R + L++
Sbjct: 1791 QTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRV 1850
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + + ++D ++ + +VKS + E EE+ + + L+ E+A
Sbjct: 1851 KELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAE 1910
Query: 216 QR 217
+R
Sbjct: 1911 ER 1912
Score = 46.4 bits (105), Expect = 1e-04
Identities = 54/232 (23%), Positives = 113/232 (48%), Gaps = 24/232 (10%)
Query: 1 MDAIKKKMQA-MKLEKDNAMDKADTCEQ--------QARDANLRAEKVNEEVRE--LQKK 49
++ K+K++ +KL +++ MD + +Q + +NL ++ +E+ E LQKK
Sbjct: 1051 LERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKK 1110
Query: 50 LAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 109
+ +++ ++E+ +++E + E + + L+R++++I E LE E T+
Sbjct: 1111 IKELQA-------RIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLE--EAGGATS 1161
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAEDADGKSDEVSRK 168
Q L ++ A E ++ + LE Q E + L + ++ L E D V +K
Sbjct: 1162 AQVELNKKREA-EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQID-NLQRVKQK 1219
Query: 169 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
L + EL++ D + S IS+ + L+ + SL+ +VSE K + ++
Sbjct: 1220 LEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLED-QVSELKTKEEEQQ 1270
Score = 45.6 bits (103), Expect = 2e-04
Identities = 46/209 (22%), Positives = 97/209 (46%), Gaps = 15/209 (7%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+Q+ D + + +++ EL+K QVE++ + LE+A LE +E ++ + E+
Sbjct: 1509 QQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLEL 1568
Query: 86 ----AALNRKVQQIEED---LEKSEERSGTAQQKLLEAQ-QSADENNRMCKVLENRAQQD 137
+ ++RK+ + +E+ L+++ R Q L+A+ +S ++ R+ K +E +
Sbjct: 1569 NQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEM 1628
Query: 138 EERMDQLTNQLKEARLLAEDADG-------KSDEVSRKLAFVEDELEVAEDRVKSGDAKI 190
E +++ E+ + G D+ R ++++L + E R A+I
Sbjct: 1629 EIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEI 1688
Query: 191 SELEEELKVVGNSLKSLEVSEEKANQRVE 219
EL L+ S K E A++RV+
Sbjct: 1689 EELWATLEQTERSRKIAEQELLDASERVQ 1717
Score = 44.4 bits (100), Expect = 5e-04
Identities = 36/177 (20%), Positives = 71/177 (40%), Gaps = 1/177 (0%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
QQ + + E+ + L L D L + + E+ + E ++ L+ +EVA
Sbjct: 1313 QQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVA 1372
Query: 87 ALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
K + + E+ EE Q+L EA++ + N C LE Q+ + ++ L
Sbjct: 1373 QWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLM 1432
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 202
++ + D K + L+ + + E + +++ + L EL V N
Sbjct: 1433 LDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKN 1489
Score = 42.3 bits (95), Expect = 0.002
Identities = 35/205 (17%), Positives = 94/205 (45%), Gaps = 7/205 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++ + ++ EK +K ++ + K+++E + LQ+ Q +DL
Sbjct: 957 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAE 1016
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
++K+ K + E+Q+ E + + +++ DLE+++ + + L AQ+S
Sbjct: 1017 EDKVNILTKAKTKLEQQVDDLEGSL----EQEKKLRMDLERAKRK---LEGDLKLAQEST 1069
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ + L+ + ++ E + L +++++ + + K E+ ++ + +E+E
Sbjct: 1070 MDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAER 1129
Query: 181 DRVKSGDAKISELEEELKVVGNSLK 205
+ + S+L EL+ + L+
Sbjct: 1130 ASRAKAEKQRSDLSRELEEISERLE 1154
Score = 42.3 bits (95), Expect = 0.002
Identities = 34/190 (17%), Positives = 85/190 (44%), Gaps = 4/190 (2%)
Query: 23 DTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATE 82
+T +Q D +KVN + + + KL Q +DL + + ++ DLE +++L E
Sbjct: 1004 ETHQQTLDDLQAEEDKVNI-LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKL---E 1059
Query: 83 AEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 142
++ +E D ++ +E+ + ++ ++ + L+ + ++ + R++
Sbjct: 1060 GDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIE 1119
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 202
+L +++ R A+ + ++SR+L + + LE A + + E E + +
Sbjct: 1120 ELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRR 1179
Query: 203 SLKSLEVSEE 212
L+ + E
Sbjct: 1180 DLEEATLQHE 1189
Score = 38.7 bits (86), Expect = 0.023
Identities = 51/259 (19%), Positives = 100/259 (38%), Gaps = 10/259 (3%)
Query: 9 QAMKLEKDNAMDKADTCEQQA--RDANLRAEKVNEEVRELQKKLAQVEEDL---ILNKN- 62
Q +LEK + + CE QA +A E ++ +Q +L QV+ ++ I K+
Sbjct: 1525 QIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE 1584
Query: 63 KLEQANKDLEEKEKQLTAT-EAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
+++Q ++ + + +T +AE+ + N R +++E DL + E + A + E+ +
Sbjct: 1585 EIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLR 1644
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
+ + K + + L QL A + +E+ L E ++
Sbjct: 1645 NYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKI 1704
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXX 238
AE + ++ L + + N+ K LE + VEE
Sbjct: 1705 AEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITD 1764
Query: 239 XXXXXKTVKKLQKEVDRLE 257
+ +KK Q LE
Sbjct: 1765 AAMMAEELKKEQDTSAHLE 1783
Score = 38.3 bits (85), Expect = 0.030
Identities = 48/219 (21%), Positives = 96/219 (43%), Gaps = 23/219 (10%)
Query: 21 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILNKNKLE---QANKD-LEE 73
K+ E++ +K +E+ + + K ++EE L+ KN L+ Q+ D L +
Sbjct: 844 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 903
Query: 74 KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
E++ L K++++ E E+ EE + K + + E + LE
Sbjct: 904 AEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELT 963
Query: 134 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR----KLAFVE------DELEVAEDRV 183
+ E+ N++K L E+ G + +++ K A E D+L+ ED+V
Sbjct: 964 LAKVEKEKHATENKVKN---LTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKV 1020
Query: 184 KSGDAKISELEEELKVVGNSL---KSLEVSEEKANQRVE 219
++LE+++ + SL K L + E+A +++E
Sbjct: 1021 NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLE 1059
Score = 35.1 bits (77), Expect = 0.28
Identities = 57/280 (20%), Positives = 117/280 (41%), Gaps = 28/280 (10%)
Query: 14 EKDNAMDKADT-CEQQARD--ANLRAEK-----VNEEVRELQKKLAQVEEDLILNKNKLE 65
+K N + KA T EQQ D +L EK + R+L+ L +E + +N +
Sbjct: 1018 DKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQ 1077
Query: 66 QANKDLEEKEKQLT----ATEAEVAA---LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
Q ++ LE+KE +++ E E A L +K+++++ +E+ E + +A++
Sbjct: 1078 QLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEK 1137
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL--AFVEDEL 176
+ L ++ ER+++ L + + + ++ R L A ++ E
Sbjct: 1138 QRSD-------LSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEA 1190
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXX 236
VA R K D+ ++EL E++ + + LE + + ++
Sbjct: 1191 MVAALRKKHADS-MAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLE 1249
Query: 237 XXXXXXXKTVKKL---QKEVDRLEDELGINKDRYKSLADE 273
V +L ++E RL ++L + R ++ A E
Sbjct: 1250 KMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGE 1289
Score = 30.3 bits (65), Expect = 8.0
Identities = 34/146 (23%), Positives = 67/146 (45%), Gaps = 18/146 (12%)
Query: 14 EKDNAMDKA-DTCEQQARDANLRAEKVNEEVRELQKKLAQVE---EDLILNKNKLEQANK 69
+K DK +Q+ + E +E R L +L +V+ E+ + L + NK
Sbjct: 1447 KKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENK 1506
Query: 70 DLEEKEKQLTATEAE----VAALNRKVQQIEED-------LEKSEERSGTAQQKLLEAQQ 118
+L+++ LT AE + L + +Q+E++ LE++E + K+L Q
Sbjct: 1507 NLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQL 1566
Query: 119 SADENNRMCKVLENRAQQDEERMDQL 144
E N++ ++ + + +E +DQL
Sbjct: 1567 ---ELNQVKSEVDRKIAEKDEEIDQL 1589
>X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal
mRNA for myosin heavy chain light meromyosin region. ).
Length = 876
Score = 61.7 bits (143), Expect = 3e-09
Identities = 48/202 (23%), Positives = 106/202 (52%), Gaps = 13/202 (6%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 73
E ++ + +A E++A+ A A + EE+++ Q A +E + KN LEQ KDL+
Sbjct: 681 EMEDIIKEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MKKN-LEQTVKDLQH 736
Query: 74 KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
+ + A + + +++Q++E + + E + Q++ +EA + ++ R K L +
Sbjct: 737 RLDE--AEQLALKGGKKQIQKLEAKVRELEGEVESEQKRNVEAVKGLHKHERKVKELTYQ 794
Query: 134 AQQD-------EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
++D ++ +D+L ++K + AE+A+ +S+ K ++ ELE AE+R
Sbjct: 795 TEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIA 854
Query: 187 DAKISELEEELKVVGNSLKSLE 208
++++++L + + V + S E
Sbjct: 855 ESQVNKLRVKSREVHTKIISEE 876
Score = 56.4 bits (130), Expect = 1e-07
Identities = 52/284 (18%), Positives = 121/284 (42%), Gaps = 14/284 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 60
++K+ MK+E D+ +T + + + +++ E++ K + + DL
Sbjct: 158 LEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQ 217
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L+Q + + + E +++ + Q E+L++ E A+ L A QS+
Sbjct: 218 RARLQQNQVEYSRQLDEKDTLETQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSS 277
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRKLAFV 172
+ C +L + ++++E +L + +A +A+ DA +++E+ +
Sbjct: 278 RHD---CDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 334
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXX 232
L+ AE+ V++ +AK + LE+ + + N ++ L + E+ N
Sbjct: 335 AQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQTNFDKIL 394
Query: 233 XXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
++ QKE L EL K+ Y+ D++++
Sbjct: 395 AEWKQKCEETHAVLESFQKESRSLSTELFKIKNAYEESLDQLET 438
Score = 52.8 bits (121), Expect = 1e-06
Identities = 54/282 (19%), Positives = 122/282 (43%), Gaps = 9/282 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
I+ + A++L+K D + E Q AN A E++R Q A +++ +
Sbjct: 546 IRSRNDAIRLKKKMEGD-LNEMEIQLNHANRMAA---EDLRNYQNTQAILKDTQL----H 597
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L+ A + E+ ++QL E L +++++ LE++E A+Q+LL+A +
Sbjct: 598 LDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLL 657
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
+ L N ++ E + Q+ ++++ A +A+ K+ + A + +EL+ +D
Sbjct: 658 HTQNTSLINTKKKLETDISQIQGEMEDIIKEARNAEEKAKKAITDAAMMAEELKKEQDTS 717
Query: 184 KSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXX 242
+ LE+ +K + + L E ++ + +++++
Sbjct: 718 AHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEAKVRELEGEVESEQKRNVEA 777
Query: 243 XKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K + K +++V L + ++ L D +D A++ Y
Sbjct: 778 VKGLHKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSY 819
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/261 (17%), Positives = 115/261 (44%), Gaps = 8/261 (3%)
Query: 5 KKKMQAMKLEKDNAMDKADT-CEQQARDANLRAEKVNEEVRELQK---KLAQVEEDLILN 60
+ K + +++ +++A Q+ +DA E VN + L+K +L EDL+++
Sbjct: 313 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMID 372
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+E+ N +K+ T + +A +K ++ LE ++ S + +L + + +
Sbjct: 373 ---VERTNAACAALDKKQTNFDKILAEWKQKCEETHAVLESFQKESRSLSTELFKIKNAY 429
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+E+ + L+ + ++ + LT Q+ E + + +V ++ + ++ LE AE
Sbjct: 430 EESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAE 489
Query: 181 DRVKSGDAKISELEEELKVVGNSL-KSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
++ + KI ++ E+ V + + + + +E+ +Q
Sbjct: 490 ASLEHEEGKILRIQLEVNQVKSEVDRKIAEKDEEIDQMKRNHIRIEESMQSTLNAEIRSR 549
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
+ KK++ +++ +E +L
Sbjct: 550 NDAIRLKKKMEGDLNEMEIQL 570
Score = 44.4 bits (100), Expect = 5e-04
Identities = 30/184 (16%), Positives = 87/184 (47%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K+ ++ ++Q ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 669 KKLETDISQIQGEMEDIIKEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLE 728
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LE + +++R + L +
Sbjct: 729 QTVKDLQHRLDEAEQLALKGGKKQIQKLEAKVRELEGEVESEQKRNVEAVKGLHKHERKV 788
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + + ++D ++ + +VKS + E EE+ V + + ++ E+A
Sbjct: 789 KELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAE 848
Query: 216 QRVE 219
+R +
Sbjct: 849 ERAD 852
Score = 41.1 bits (92), Expect = 0.004
Identities = 47/218 (21%), Positives = 102/218 (46%), Gaps = 14/218 (6%)
Query: 12 KLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDL 71
KL +++AMD + ++Q D L+ ++ E+ LQ K+ + + + K+++ +
Sbjct: 1 KLAQESAMDIEN--DKQQLDEKLKKKEF--EMSGLQSKIEDEQALGMQLQKKIKELQARI 56
Query: 72 EEKEKQLTA---TEAEVAALNRKV-QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMC 127
EE E+++ A + A+ L + +++EE E+ EE G ++ ++ E +M
Sbjct: 57 EELEEEIEAERTSRAKAEKLRSDLSRELEEISERLEEAVGATSTQIEMNKKREAEFQKMR 116
Query: 128 KVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
+ LE Q E L + ++ L E D V +KL + E+++ D + S
Sbjct: 117 RDLEEATLQHEATAATLRKKHADSVAELGEQID-NLQRVKQKLEKEKSEMKMEIDDLASN 175
Query: 187 DAKISE----LEEELKVVGNSLKSLEVSEEKANQRVEE 220
+S+ LE+ + + + L ++ EE+ + + +
Sbjct: 176 METVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLIND 213
Score = 39.9 bits (89), Expect = 0.010
Identities = 30/161 (18%), Positives = 83/161 (51%), Gaps = 9/161 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ +KK ++ + + +D+A+ + + + +K+ +VREL+ +VE + N
Sbjct: 720 LERMKKNLEQTVKDLQHRLDEAE--QLALKGGKKQIQKLEAKVRELE---GEVESEQKRN 774
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
++ +K E K K+LT E + + ++++ ++K + + + +++ EA++ +
Sbjct: 775 VEAVKGLHKH-ERKVKELTYQTEED---RKNILRLQDLVDKLQAKVKSYKRQAEEAEEQS 830
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
+ N + +++ ++ EER D +Q+ + R+ + + K
Sbjct: 831 NVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVHTK 871
Score = 35.9 bits (79), Expect = 0.16
Identities = 49/228 (21%), Positives = 93/228 (40%), Gaps = 14/228 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQ--QARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
++ + A L K +A A+ EQ + + EK E++ LA E + K
Sbjct: 124 LQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAK 183
Query: 62 NKLEQANKDLEEKEKQLTATEAE-------VAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
LE+ + LE++ ++ E E + A ++QQ + + + + T + +L
Sbjct: 184 GNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQQNQVEYSRQLDEKDTLETQLS 243
Query: 115 EAQQS-ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD-EVSRKLAFV 172
+Q+ + + + LE + L + + LL E + + + + + A
Sbjct: 244 RGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMS 303
Query: 173 EDELEVAEDRVK-SGDA--KISELEEELKVVGNSLKSLEVSEEKANQR 217
+ EVA+ R K DA + ELEE K + L+ E E N +
Sbjct: 304 KANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAK 351
>AK093463-1|BAC04173.1| 650|Homo sapiens protein ( Homo sapiens
cDNA FLJ36144 fis, clone TESTI2025022, weakly similar to
TRICHOHYALIN. ).
Length = 650
Score = 61.7 bits (143), Expect = 3e-09
Identities = 41/174 (23%), Positives = 93/174 (53%), Gaps = 6/174 (3%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E++ R+ + + E++ +K+L + E++L + +L + K L E+E+Q+ E ++
Sbjct: 299 EERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKK-LREQEEQMQEQEEKM 357
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA-DENNRMCKVLENRAQQDEERMDQL 144
K+++ EE + + EER ++++ E +Q D+ RM + + R ++ EERM +
Sbjct: 358 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ-DERLREKEERMREQ 416
Query: 145 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 198
++ + E+ K E +K E++++ E+R++ + K+ E EE ++
Sbjct: 417 EKMWEQVEKMREEK--KMQEQEKKTRDQEEKMQ-EEERIREREKKMREEEETMR 467
Score = 56.4 bits (130), Expect = 1e-07
Identities = 43/217 (19%), Positives = 105/217 (48%), Gaps = 9/217 (4%)
Query: 12 KLEKDNA--MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE-----EDLILNKNKL 64
+L+K NA +K E + + L +++ ++ + L QV+ E++ + +L
Sbjct: 222 ELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEEL 281
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
+ K + ++E+++ E + K+++ EE + + E+R +++L E ++ E
Sbjct: 282 REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQK 341
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
++ + E + Q+ EE+M + +++E + + E +++ E ++ E+R+
Sbjct: 342 KL-REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW 400
Query: 185 SGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEE 220
D ++ E EE ++ + +E + EEK Q E+
Sbjct: 401 EQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEK 437
Score = 55.2 bits (127), Expect = 2e-07
Identities = 41/219 (18%), Positives = 104/219 (47%), Gaps = 8/219 (3%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDLILNKN 62
K ++Q E +++A Q + L+ E + EE+RE +KK+ + EE + +
Sbjct: 241 KSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEE 300
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+L + + E+E+++ E + +++++ E++L + +++ ++++ E ++ E
Sbjct: 301 RLREQEGKMREQEEKMWRQEKRLREQEKELREQEKEL-REQKKLREQEEQMQEQEEKMWE 359
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
+ E + + EER+ + Q++E D + + E +L E+ + E
Sbjct: 360 QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKM 419
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEE-KANQRVEE 220
+ ++ ++ EE K+ K+ + E+ + +R+ E
Sbjct: 420 WE----QVEKMREEKKMQEQEKKTRDQEEKMQEEERIRE 454
Score = 54.4 bits (125), Expect = 4e-07
Identities = 43/191 (22%), Positives = 98/191 (51%), Gaps = 4/191 (2%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-QKKLAQVEEDLILNKN 62
++++ Q M+ +++ M + D ++ + EK+ E+V ++ ++K Q +E ++
Sbjct: 385 MREQEQKMR-DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQE 443
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+ Q + + E+EK++ E + K+Q+ EE++ + EE+ QQ+L E ++ E
Sbjct: 444 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE-WQQQRLPEQKEKLWE 502
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR-KLAFVEDELEVAED 181
+M + E +Q+E+ DQ +E ++ E+ +E+ R K + D+ E ++
Sbjct: 503 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWQEEKMWGQEEMMREKEERIRDQKEKMQE 562
Query: 182 RVKSGDAKISE 192
R+ + + SE
Sbjct: 563 RLPEHEERCSE 573
Score = 48.0 bits (109), Expect = 4e-05
Identities = 42/197 (21%), Positives = 94/197 (47%), Gaps = 8/197 (4%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKV----NEEVRELQKKLAQVEEDLILN 60
K + Q K+ + + E + ++ LR +K E+++E ++K+ + EE +
Sbjct: 308 KMREQEEKMWRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQ 367
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ K+ + + L E+EKQ+ E ++ ++ + +E L + EER Q+K+ E +
Sbjct: 368 EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM-REQEKMWEQVEKM 426
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
E +M + E + + EE+M Q +++E + + E K+ E+ + E
Sbjct: 427 REEKKM-QEQEKKTRDQEEKM-QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 484
Query: 181 DRVKSGDAKISELEEEL 197
++ + ++ E +E+L
Sbjct: 485 EK-EWQQQRLPEQKEKL 500
Score = 47.2 bits (107), Expect = 7e-05
Identities = 38/200 (19%), Positives = 94/200 (47%), Gaps = 7/200 (3%)
Query: 27 QQARDA-NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
Q+A A + R +K + + EL K+ + +L N E+ K E +++L E+E
Sbjct: 182 QRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEK 241
Query: 86 AALNRKVQQIEEDLEKS-----EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 140
+ + V++++ LE++ + ++ T Q+++ ++ E + + E + + EER
Sbjct: 242 SEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEER 301
Query: 141 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 200
+ + +++E + + E ++L E EL + +++ + ++ E EE++
Sbjct: 302 LREQEGKMREQEEKMWRQEKRLREQEKELREQEKELR-EQKKLREQEEQMQEQEEKMWEQ 360
Query: 201 GNSLKSLEVSEEKANQRVEE 220
++ E + +R+ E
Sbjct: 361 EEKMREQEEKMWRQEERLWE 380
>Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 61.3 bits (142), Expect = 4e-09
Identities = 47/210 (22%), Positives = 111/210 (52%), Gaps = 13/210 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKKM++ ++ E + A+ + E++A+ A A + EE+++ Q A +E +
Sbjct: 1729 KKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 1785
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E +LE ++R+ + + + +
Sbjct: 1786 KN-MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRK 1844
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
+++ E + + + ++ +D+L ++K + AE+A+ +++ K V+ E
Sbjct: 1845 SERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 1904
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLK 205
L+ AE+R ++++++L + + +G K
Sbjct: 1905 LDEAEERADIAESQVNKLRAKSRDIGAKQK 1934
Score = 56.0 bits (129), Expect = 1e-07
Identities = 54/226 (23%), Positives = 109/226 (48%), Gaps = 15/226 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 59
++ ++K+++ KLE +A+++A+ + LRA+ + N+ E+++KLA+ +E++
Sbjct: 1528 LEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 1587
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
K ++ L+ T + EV + +K +E DL + E + A + EAQ+
Sbjct: 1588 AKRNHQRVVDSLQTSLDAETRSRNEVLRVKKK---MEGDLNEMEIQLSHANRMAAEAQKQ 1644
Query: 120 ADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVSRKLA 170
+ K L++ + +++ + + N L +A L A + E SRKLA
Sbjct: 1645 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1704
Query: 171 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
E EL +RV+ ++ + L + K + + L L+ E+A Q
Sbjct: 1705 --EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQ 1748
Score = 54.0 bits (124), Expect = 6e-07
Identities = 45/214 (21%), Positives = 99/214 (46%), Gaps = 12/214 (5%)
Query: 11 MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE----Q 66
++ E+DN D + C+Q ++ ++ E +E+ E + ++ +L K KLE +
Sbjct: 893 VQAEQDNLNDAEERCDQLIKN-KIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSE 951
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
KD+++ E L E E A KV+ + E++ +E KL + +++ E ++
Sbjct: 952 LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDE----IIAKLTKEKKALQEAHQ- 1006
Query: 127 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
+ L++ Q +E++++ L+ + +D +G ++ + +E E +K
Sbjct: 1007 -QALDD-LQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLT 1064
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
I +LE + + LK E + N ++E+
Sbjct: 1065 QESIMDLENDKLQLEEKLKKKEFDINQQNSKIED 1098
Score = 52.8 bits (121), Expect = 1e-06
Identities = 42/192 (21%), Positives = 86/192 (44%), Gaps = 4/192 (2%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1424 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1483
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
L ++ E LE + + Q+++ + + E + LE +Q E +L
Sbjct: 1484 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQ 1543
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
+ L+EA E +GK + +L F + + E+ E ++ D ++ + + + V +SL+
Sbjct: 1544 SALEEAEASLEHEEGKI--LRAQLEFNQIKAEI-ERKLAEKDEEMEQAKRNHQRVVDSLQ 1600
Query: 206 -SLEVSEEKANQ 216
SL+ N+
Sbjct: 1601 TSLDAETRSRNE 1612
Score = 52.8 bits (121), Expect = 1e-06
Identities = 43/285 (15%), Positives = 120/285 (42%), Gaps = 1/285 (0%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D+++ + A ++ + E + ++ N E QK++ ++ L
Sbjct: 1596 VDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDT 1655
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L+ A + ++ ++ + E L +++++ +E++E A+Q+L+E +
Sbjct: 1656 QIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERV 1715
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L N+ ++ E + QL ++++EA +A+ K+ + A + +EL+ +
Sbjct: 1716 QLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQ 1775
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + +E+ +K + + L E ++ + +++++
Sbjct: 1776 DTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRN 1835
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K ++ + L + +K L D +D ++ Y
Sbjct: 1836 AESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAY 1880
Score = 51.2 bits (117), Expect = 4e-06
Identities = 41/178 (23%), Positives = 88/178 (49%), Gaps = 9/178 (5%)
Query: 45 ELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 104
E +K++A ++E+ K LE++ +E E+++ + E L +VQ +++L +EE
Sbjct: 846 ETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEE 905
Query: 105 RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 164
R + ++ + E N R + +EE +LT + ++ + D+
Sbjct: 906 RCDQLIKNKIQLEAKVKEMNE-------RLEDEEEMNAELTAKKRKLEDECSELKKDIDD 958
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA--NQRVEE 220
+ LA VE E E++VK+ +++ L+E + + K+L+ + ++A + +VEE
Sbjct: 959 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEE 1016
Score = 50.4 bits (115), Expect = 7e-06
Identities = 59/293 (20%), Positives = 131/293 (44%), Gaps = 20/293 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++ + ++ EK +K ++ + K+ +E + LQ+ Q +DL +
Sbjct: 956 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVE 1015
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
++K+ +K + E+Q+ E + + +++ DLE++ +R KL +
Sbjct: 1016 EDKVNSLSKSKVKLEQQVDDLEGSL----EQEKKVRMDLERA-KRKLEGDLKLTQESIMD 1070
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
EN+++ LE + ++ E ++Q +++++ + LA K E ++ +E+ELE AE
Sbjct: 1071 LENDKL--QLEEKLKKKEFDINQQNSKIEDEQALALQLQKKLKENQARIEELEEELE-AE 1127
Query: 181 DRVKSGDAKI-SELEEELKVVGNSLK----SLEVSEEKANQRVEEFXXXXXXXXXXXXXX 235
++ K+ S+L EL+ + L+ + V E +R EF
Sbjct: 1128 RTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQH 1187
Query: 236 XXXXXXXXK----TVKKLQKEVD---RLEDELGINKDRYKSLADEMDSTFAEL 281
K +V +L +++D R++ +L K +K D++ S ++
Sbjct: 1188 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQI 1240
Score = 50.4 bits (115), Expect = 7e-06
Identities = 66/290 (22%), Positives = 118/290 (40%), Gaps = 33/290 (11%)
Query: 12 KLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDL 71
KLEK+ + K + D E++ + L+K +E+ + KLE+A + L
Sbjct: 1218 KLEKEKSEFKLEL-----DDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSL 1272
Query: 72 E--------------EKEKQLTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQQKLL 114
E +QL EA ++ L R Q EDL++ E G A+ L
Sbjct: 1273 NDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALA 1332
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVS 166
A QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 1333 HALQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE 1389
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXX 226
+ L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1390 EAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR 1449
Query: 227 XXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
++ QKE L EL K+ Y+ + +++
Sbjct: 1450 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1499
Score = 50.4 bits (115), Expect = 7e-06
Identities = 45/261 (17%), Positives = 110/261 (42%), Gaps = 8/261 (3%)
Query: 5 KKKMQAMKLEKDNAMDKADT-CEQQARDANLRAEKVNEEVRELQK---KLAQVEEDLILN 60
+ K + +++ +++A Q+ +DA E VN + L+K +L EDL+++
Sbjct: 1374 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1433
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ A L++K++ AE +K ++ + +LE S++ + + +L + + +
Sbjct: 1434 VERSNAAAAALDKKQRNFDKILAE---WKQKYEESQSELESSQKEARSLSTELFKLKNAY 1490
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+E+ + + + +E + LT QL E + + ++ + ++ LE AE
Sbjct: 1491 EESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAE 1550
Query: 181 DRVKSGDAKISELEEELKVVGNSL-KSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
++ + KI + E + + + L +E+ Q
Sbjct: 1551 ASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSR 1610
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
+ KK++ +++ +E +L
Sbjct: 1611 NEVLRVKKKMEGDLNEMEIQL 1631
Score = 48.4 bits (110), Expect = 3e-05
Identities = 53/261 (20%), Positives = 117/261 (44%), Gaps = 15/261 (5%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++KM ++ EK++ + + DA R +++ + +L+ K+ ++ E L
Sbjct: 875 LEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERL----ED 930
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE-AQQSADE 122
E+ N +L K+++L E E + L + + +E L K E+ + K+ ++ A
Sbjct: 931 EEEMNAELTAKKRKL---EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 987
Query: 123 NNRMCKVL-ENRAQQD--EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+ + K+ E +A Q+ ++ +D L + + L++ +V +E E +V
Sbjct: 988 DEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVR 1047
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + AK +LE +LK+ S+ LE + + +++++
Sbjct: 1048 MDLER---AK-RKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQALA 1103
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
K +K+ Q ++ LE+EL
Sbjct: 1104 LQLQKKLKENQARIEELEEEL 1124
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/184 (15%), Positives = 88/184 (47%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K+ ++ +LQ ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 1730 KKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1789
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LE + +++R + ++++
Sbjct: 1790 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRI 1849
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + L ++D ++ + +VK+ + E EE+ + + ++ ++A
Sbjct: 1850 KELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAE 1909
Query: 216 QRVE 219
+R +
Sbjct: 1910 ERAD 1913
Score = 31.1 bits (67), Expect = 4.6
Identities = 50/271 (18%), Positives = 107/271 (39%), Gaps = 26/271 (9%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNE--EVRELQKKLAQVEEDLILNKN 62
K++ + K+ +D +++A T + +A A LR + + E+ E L +V++ L K+
Sbjct: 1168 KREAEFQKMRRD--LEEA-TLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1224
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSAD 121
+ + D+ +Q+ +A + ++R ++ Q E K EE + + +
Sbjct: 1225 EFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQT 1284
Query: 122 ENNRMCKVLENRAQ----------QDEERMDQLTNQLKEARLLAEDADGKS-DEVSRKLA 170
EN + + LE + ++M+ L QL+E +GK+ + ++ L
Sbjct: 1285 ENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEE--------EGKAKNALAHALQ 1336
Query: 171 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVS-EEKANQRVEEFXXXXXXXX 229
+ ++ ++ + +EL+ L + + E A QR EE
Sbjct: 1337 SARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1396
Query: 230 XXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
L+K RL++E+
Sbjct: 1397 QRLQDAEEAVEAVNAKCSSLEKTKHRLQNEI 1427
>X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein.
Length = 2185
Score = 61.3 bits (142), Expect = 4e-09
Identities = 53/223 (23%), Positives = 111/223 (49%), Gaps = 14/223 (6%)
Query: 5 KKKMQAMKLEKDNAMDKADT-CEQQARDANLRAEKVN---EEVRELQKKLAQVEEDLILN 60
KKK Q+ + N + + E ++++A + E++N EE+ + K+ ++ ++ +
Sbjct: 1446 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDD 1505
Query: 61 KNKLEQANKDLEEKEKQLTAT----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
K+K+E+ +LE + K TA E + +++ + E L+ ++ ++L++
Sbjct: 1506 KSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQK 1565
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
Q E + + +NR ++ EE++ L NQ+ + E + + V+ + E+EL
Sbjct: 1566 LQHFQE---LGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEEL 1622
Query: 177 EVAEDRVKS-GDAKISELEE--ELKVVGNSLKSLEVSEEKANQ 216
+ EDR++S AK++EL+ E K+ + L EEK Q
Sbjct: 1623 KALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQ 1665
Score = 56.4 bits (130), Expect = 1e-07
Identities = 63/292 (21%), Positives = 128/292 (43%), Gaps = 21/292 (7%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQA---RDANLRAE-KVNEEVRELQKKLAQVEED--LI 58
K++ + EK+ ++ D Q+ +D ++ + K+ ++R+ + + Q+E+D ++
Sbjct: 306 KEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMV 365
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
+ + K Q ++ LE KE+++ + + + + +++ E EKSE + +K L Q
Sbjct: 366 IAETK-RQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQ 424
Query: 119 SADENNRMCKV-----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE--VSRKLAF 171
+E R K ++ + EE L +L + D KS E +++
Sbjct: 425 KTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKL 484
Query: 172 VEDELEVAEDRV-KSGDAKISELEEELKVVGNSLKS--LEVSEEKANQR---VEEFXXXX 225
E EL E + K + E +E++KV +S L++S+EK Q +EE
Sbjct: 485 HEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQK 544
Query: 226 XXXXXXXXXXXXXXXXXXKTVKKLQKEVD-RLEDELGINKDRYKSLADEMDS 276
+T + E++ LE L NK++ K LA +++
Sbjct: 545 KAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEA 596
Score = 50.0 bits (114), Expect = 9e-06
Identities = 41/237 (17%), Positives = 109/237 (45%), Gaps = 8/237 (3%)
Query: 43 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 102
V EL+ +L Q+ E+ +QA LEEKE Q+ + +A++ +L + + ++++
Sbjct: 1271 VSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQ 1330
Query: 103 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
++ + + + + ++ EN +++ ++ + + L+ QL + + +++ S
Sbjct: 1331 QQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLS 1390
Query: 163 DE----VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
++ S + + E++ E+ D+V+ K+ L +E K+ ++L+ ++ K ++
Sbjct: 1391 EKEAAISSLRKQYDEEKCELL-DQVQDLSFKVDTLSKE-KI--SALEQVDDWSNKFSEWK 1446
Query: 219 EEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMD 275
++ K + ++++ L++EL R+ L EM+
Sbjct: 1447 KKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEME 1503
Score = 48.0 bits (109), Expect = 4e-05
Identities = 49/217 (22%), Positives = 99/217 (45%), Gaps = 12/217 (5%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
+K+ A LE A + A + +R + E++ E + E+ ++ ++ + + + + KL
Sbjct: 996 EKQFNAKMLEMAQA-NSAGISDAVSRLETNQKEQI-ESLTEVHRR--ELNDVISIWEKKL 1051
Query: 65 EQANKDLEE-KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
Q ++L+E E QL E EVA L +K+ EK E K +Q N
Sbjct: 1052 NQQAEELQEIHEIQLQEKEQEVAELKQKILLF--GCEKEEMNKEITWLKEEGVKQDTTLN 1109
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
L+ + +Q ++ L + + E + ++ ++ F++++L +
Sbjct: 1110 E-----LQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLA 1164
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ K+SEL +LK +SL+ S EK+N+ +E+
Sbjct: 1165 EEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLED 1201
Score = 43.6 bits (98), Expect = 8e-04
Identities = 38/226 (16%), Positives = 99/226 (43%), Gaps = 9/226 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K+K+ EK+ + +++ + ++ E++++ + + +D K
Sbjct: 1076 LKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAH 1135
Query: 64 LEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEEDLEKSEERSGTAQQKLLEA 116
LE+ DL + K+ T + ++ L RKV ++ L+ ++E + + ++
Sbjct: 1136 LEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKS 1195
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL--LAEDADGKSDEVSRKLAFVED 174
+S ++ + K L + + T L EA+ L + K++ + +++ +
Sbjct: 1196 NKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQH 1255
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
++ + +SELE +L+ + +L +S ++A ++EE
Sbjct: 1256 RTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEE 1301
Score = 42.7 bits (96), Expect = 0.001
Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 22/218 (10%)
Query: 2 DAIKKKMQAMKLEKD-NAMDKADT-CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
D K K KLE D N K +T ++Q + + AE+ +V EL KL +E+
Sbjct: 1128 DETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQS 1187
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
K+ E++NK LE+K + E+A Q++ +K+E LLEA+ +
Sbjct: 1188 LKSSHEKSNKSLEDKSLEFKKLSEELAI------QLDICCKKTE--------ALLEAKTN 1233
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
N K N T ++KEA L+ + + R+L ++ L ++
Sbjct: 1234 ELINISSSKT--NAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNIS 1291
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 217
+ ++ E E ++K + ++SL V+E++A Q+
Sbjct: 1292 ---FQQATHQLEEKENQIKSMKADIESL-VTEKEALQK 1325
Score = 42.7 bits (96), Expect = 0.001
Identities = 41/194 (21%), Positives = 82/194 (42%), Gaps = 13/194 (6%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E Q D + E ++L K++ ++++DL + + + +Q +LE +K+ E
Sbjct: 1922 EAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQ---ELEILKKEYDQEREE- 1977
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
K++Q +EDLE + + Q + E + E + E + L
Sbjct: 1978 -----KIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLE 2032
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL- 204
+ +E L + K D++ R E+ L+ E+ + AK+ +L+ +L+ +
Sbjct: 2033 SHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEM---TAKVRDLQTQLEELQKKYQ 2089
Query: 205 KSLEVSEEKANQRV 218
+ LE E N V
Sbjct: 2090 QKLEQEENPGNDNV 2103
Score = 40.7 bits (91), Expect = 0.006
Identities = 37/187 (19%), Positives = 89/187 (47%), Gaps = 15/187 (8%)
Query: 48 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 107
K L +++ + +N L++ + ++ ++Q T +E AL ++ + ++LEK ++
Sbjct: 279 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHM 338
Query: 108 TAQQKLLEAQQSAD------ENNRMCKVLENRAQ------QDEERMDQLTNQLKEARLLA 155
+ KL+ + A E ++ + E + Q EE + QL +++K+
Sbjct: 339 AEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQG 398
Query: 156 EDADGKSDEVSRKLAF--VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E+ + E S + AF +E L A+ ++ +E++E++K + + + +S ++
Sbjct: 399 EEL-REQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQ 457
Query: 214 ANQRVEE 220
RV++
Sbjct: 458 ELSRVKQ 464
Score = 40.3 bits (90), Expect = 0.007
Identities = 43/217 (19%), Positives = 97/217 (44%), Gaps = 13/217 (5%)
Query: 4 IKKKMQAMKLEKDNAMDKA---DTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ + + A+ L K+ +K + +Q D N++ + + + E + ++ + +
Sbjct: 1348 LSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQN-SISLSEKEAAISSLRKQYDEE 1406
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K +L +DL K T ++ +++AL +Q+++ K E AQ + + Q +
Sbjct: 1407 KCELLDQVQDLSFKVD--TLSKEKISAL----EQVDDWSNKFSEWKKKAQSRFTQHQNTV 1460
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
E ++ A + +E+++ L +L + + G+ ++ K+ E LE
Sbjct: 1461 KELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLET-- 1518
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 217
+KS A+I ELE+ + ++SL + NQ+
Sbjct: 1519 -ELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQ 1554
Score = 38.7 bits (86), Expect = 0.023
Identities = 38/216 (17%), Positives = 93/216 (43%), Gaps = 7/216 (3%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
+ ++++MK + ++ + + + +++ + A + + +L+K+L++ + L K +L
Sbjct: 1303 ENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEEL 1362
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
++ ++ KQLT + L + E++ S R ++K Q D +
Sbjct: 1363 KEKKVEISSLSKQLTDLNVQ---LQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSF 1419
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
++ L E++D +N+ E + A+ + ++L +LE+
Sbjct: 1420 KV-DTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQI---QLELKSKEAY 1475
Query: 185 SGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
D +I+ L+EEL L+ E ++E+
Sbjct: 1476 EKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEK 1511
Score = 38.3 bits (85), Expect = 0.030
Identities = 44/199 (22%), Positives = 86/199 (43%), Gaps = 23/199 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +K + MK E + MD+ QQ D+ ++ +V+ ++ +K L
Sbjct: 707 LSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS--IQRTEKAL---------- 754
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K+++ Q L+E++K L +A V+ +E D+++SE A KL Q
Sbjct: 755 KDQINQLELLLKERDKHLKEHQAH-------VENLEADIKRSEGELQQASAKLDVFQSYQ 807
Query: 121 DENNRMCKVLENR-AQQDEERMDQLTNQLKEARLLAEDADGKSD---EVSRKLAFVEDEL 176
+ K E + AQ ++ +D T ++ + +AE K D E+ V+D +
Sbjct: 808 SATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLM 867
Query: 177 EVAEDRVKSGDAKISELEE 195
+ E + + K+ L +
Sbjct: 868 QQLEKQNSEMEQKVKSLTQ 886
Score = 36.7 bits (81), Expect = 0.092
Identities = 38/212 (17%), Positives = 96/212 (45%), Gaps = 6/212 (2%)
Query: 4 IKKKMQAMKLEKDNAM-DKADTCEQQARDANLRA-EKVNEEVRELQKKLAQVEEDLILNK 61
++K + + EK+ + DK + + N + EK++ + EL+ +++ E ++ +
Sbjct: 642 MEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSE-VLKAR 700
Query: 62 NKLEQANKDLEEK-EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+KLE+ L+++ +K EA++ QQ + + K E S +K L+ Q
Sbjct: 701 HKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQ--I 758
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
++ + K + ++ + ++ L +K + + A K D + ++ + E
Sbjct: 759 NQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYE 818
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
+++ K+ +LE E ++ + +E ++
Sbjct: 819 EQLAQLQQKLLDLETERILLTKQVAEVEAQKK 850
Score = 36.7 bits (81), Expect = 0.092
Identities = 56/223 (25%), Positives = 103/223 (46%), Gaps = 23/223 (10%)
Query: 3 AIKKKMQAMK--LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++K +++ K LE N K+ E +A + L +E ++ EL++K Q + +
Sbjct: 1596 SMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESA-AKLAELKRKAEQ--KIAAIK 1652
Query: 61 KNKLEQANKDLEEKEKQLT-ATEAEVAALNRKVQQIEEDLEKSEER---SGTAQQKLLEA 116
K L Q +EEKE+Q TE+ ++ LN K+Q+ E ++ EE+ ++Q + L
Sbjct: 1653 KQLLSQ----MEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIV 1708
Query: 117 QQSADENNRMCKVLENRAQ-----QDEERMDQLTNQLKE-ARLLAEDADGKSDEVSRKLA 170
+SA + E +Q EE++ L L E +LL K + VS +
Sbjct: 1709 PRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVS---S 1765
Query: 171 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E + E +K A+ + E++ ++G+ + LE +K
Sbjct: 1766 HFEMRCQYQERLIKLEHAEAKQHEDQ-SMIGHLQEELEEKNKK 1807
Score = 36.3 bits (80), Expect = 0.12
Identities = 34/186 (18%), Positives = 90/186 (48%), Gaps = 2/186 (1%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK-EKQLTATEAEVAALNRKVQQI 95
E ++ E+ E+ K ++EE+L + K++ ++ ++LE K ++Q + +V ++ ++ +
Sbjct: 687 ESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS 746
Query: 96 EEDLEKS-EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 154
+ EK+ +++ + L E + E+ + LE ++ E + Q + +L +
Sbjct: 747 IQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSY 806
Query: 155 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
++ +LA ++ +L E +++E+E + K V L + ++ +
Sbjct: 807 QSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDL 866
Query: 215 NQRVEE 220
Q++E+
Sbjct: 867 MQQLEK 872
Score = 35.1 bits (77), Expect = 0.28
Identities = 57/287 (19%), Positives = 127/287 (44%), Gaps = 22/287 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED------ 56
++++++ +K E + M K+ EQ A+ L +++ + +EL KKL E +
Sbjct: 454 SLQQELSRVKQEVVDVMKKSSE-EQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMK 512
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV-QQIEEDLEKSEERSGTAQQKLLE 115
+ L K++ E K +EKE+Q + E+ + + + E L ++ + T + ++LE
Sbjct: 513 VALEKSQSEYL-KISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILE 571
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQL-KEARLLAEDADGKSDEVSRKL-AFVE 173
+ S +++ + K N+++ ++ N+ KE ++ E + + + + A
Sbjct: 572 LESSLEKSLQENK---NQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWT 628
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXX 233
++L+V + + ++ K+ E E+ K LK E+ + +EE
Sbjct: 629 EKLQVLKQQYQTEMEKLREKCEQEKET--LLKDKEIIFQA---HIEEMNEKTLEKLDVKQ 683
Query: 234 XXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
V K + +LE+EL + KD+ + E+++ E
Sbjct: 684 TELESLSSELSEVLKARH---KLEEELSVLKDQTDKMKQELEAKMDE 727
Score = 31.1 bits (67), Expect = 4.6
Identities = 47/278 (16%), Positives = 102/278 (36%), Gaps = 17/278 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+ ++ + + A + + E Q + E + E LQK+ ++ ++
Sbjct: 1281 LTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESC 1340
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ Q K+L E +T + E+ ++ + + L ++ Q S +
Sbjct: 1341 ITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLN----------VQLQNSISLS 1390
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
+ + R Q DEE+ +L +Q+++ L+ D S E L V+D +
Sbjct: 1391 EKEAAISSLRKQYDEEKC-ELLDQVQD---LSFKVDTLSKEKISALEQVDDWSNKFSEWK 1446
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXX 243
K ++ ++ + +K + LE+ ++A ++ E+
Sbjct: 1447 KKAQSRFTQHQNTVKEL---QIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEME 1503
Query: 244 KTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K++K+ LE EL R L D + E+
Sbjct: 1504 DDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEI 1541
>U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein.
Length = 2230
Score = 61.3 bits (142), Expect = 4e-09
Identities = 53/223 (23%), Positives = 111/223 (49%), Gaps = 14/223 (6%)
Query: 5 KKKMQAMKLEKDNAMDKADT-CEQQARDANLRAEKVN---EEVRELQKKLAQVEEDLILN 60
KKK Q+ + N + + E ++++A + E++N EE+ + K+ ++ ++ +
Sbjct: 1446 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDD 1505
Query: 61 KNKLEQANKDLEEKEKQLTAT----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
K+K+E+ +LE + K TA E + +++ + E L+ ++ ++L++
Sbjct: 1506 KSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQK 1565
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
Q E + + +NR ++ EE++ L NQ+ + E + + V+ + E+EL
Sbjct: 1566 LQHFQE---LGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEEL 1622
Query: 177 EVAEDRVKS-GDAKISELEE--ELKVVGNSLKSLEVSEEKANQ 216
+ EDR++S AK++EL+ E K+ + L EEK Q
Sbjct: 1623 KALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQ 1665
Score = 56.4 bits (130), Expect = 1e-07
Identities = 63/292 (21%), Positives = 128/292 (43%), Gaps = 21/292 (7%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQA---RDANLRAE-KVNEEVRELQKKLAQVEED--LI 58
K++ + EK+ ++ D Q+ +D ++ + K+ ++R+ + + Q+E+D ++
Sbjct: 306 KEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMV 365
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
+ + K Q ++ LE KE+++ + + + + +++ E EKSE + +K L Q
Sbjct: 366 IAETK-RQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQ 424
Query: 119 SADENNRMCKV-----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE--VSRKLAF 171
+E R K ++ + EE L +L + D KS E +++
Sbjct: 425 KTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKL 484
Query: 172 VEDELEVAEDRV-KSGDAKISELEEELKVVGNSLKS--LEVSEEKANQR---VEEFXXXX 225
E EL E + K + E +E++KV +S L++S+EK Q +EE
Sbjct: 485 HEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQK 544
Query: 226 XXXXXXXXXXXXXXXXXXKTVKKLQKEVD-RLEDELGINKDRYKSLADEMDS 276
+T + E++ LE L NK++ K LA +++
Sbjct: 545 KAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEA 596
Score = 50.0 bits (114), Expect = 9e-06
Identities = 41/237 (17%), Positives = 109/237 (45%), Gaps = 8/237 (3%)
Query: 43 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 102
V EL+ +L Q+ E+ +QA LEEKE Q+ + +A++ +L + + ++++
Sbjct: 1271 VSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQ 1330
Query: 103 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
++ + + + + ++ EN +++ ++ + + L+ QL + + +++ S
Sbjct: 1331 QQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLS 1390
Query: 163 DE----VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
++ S + + E++ E+ D+V+ K+ L +E K+ ++L+ ++ K ++
Sbjct: 1391 EKEAAISSLRKQYDEEKCELL-DQVQDLSFKVDTLSKE-KI--SALEQVDDWSNKFSEWK 1446
Query: 219 EEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMD 275
++ K + ++++ L++EL R+ L EM+
Sbjct: 1447 KKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEME 1503
Score = 48.0 bits (109), Expect = 4e-05
Identities = 49/217 (22%), Positives = 99/217 (45%), Gaps = 12/217 (5%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
+K+ A LE A + A + +R + E++ E + E+ ++ ++ + + + + KL
Sbjct: 996 EKQFNAKMLEMAQA-NSAGISDAVSRLETNQKEQI-ESLTEVHRR--ELNDVISIWEKKL 1051
Query: 65 EQANKDLEE-KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
Q ++L+E E QL E EVA L +K+ EK E K +Q N
Sbjct: 1052 NQQAEELQEIHEIQLQEKEQEVAELKQKILLF--GCEKEEMNKEITWLKEEGVKQDTTLN 1109
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
L+ + +Q ++ L + + E + ++ ++ F++++L +
Sbjct: 1110 E-----LQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLA 1164
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ K+SEL +LK +SL+ S EK+N+ +E+
Sbjct: 1165 EEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLED 1201
Score = 43.6 bits (98), Expect = 8e-04
Identities = 38/226 (16%), Positives = 99/226 (43%), Gaps = 9/226 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K+K+ EK+ + +++ + ++ E++++ + + +D K
Sbjct: 1076 LKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAH 1135
Query: 64 LEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEEDLEKSEERSGTAQQKLLEA 116
LE+ DL + K+ T + ++ L RKV ++ L+ ++E + + ++
Sbjct: 1136 LEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKS 1195
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL--LAEDADGKSDEVSRKLAFVED 174
+S ++ + K L + + T L EA+ L + K++ + +++ +
Sbjct: 1196 NKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQH 1255
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
++ + +SELE +L+ + +L +S ++A ++EE
Sbjct: 1256 RTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEE 1301
Score = 42.7 bits (96), Expect = 0.001
Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 22/218 (10%)
Query: 2 DAIKKKMQAMKLEKD-NAMDKADT-CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
D K K KLE D N K +T ++Q + + AE+ +V EL KL +E+
Sbjct: 1128 DETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQS 1187
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
K+ E++NK LE+K + E+A Q++ +K+E LLEA+ +
Sbjct: 1188 LKSSHEKSNKSLEDKSLEFKKLSEELAI------QLDICCKKTE--------ALLEAKTN 1233
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
N K N T ++KEA L+ + + R+L ++ L ++
Sbjct: 1234 ELINISSSKT--NAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNIS 1291
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 217
+ ++ E E ++K + ++SL V+E++A Q+
Sbjct: 1292 ---FQQATHQLEEKENQIKSMKADIESL-VTEKEALQK 1325
Score = 42.7 bits (96), Expect = 0.001
Identities = 41/194 (21%), Positives = 82/194 (42%), Gaps = 13/194 (6%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E Q D + E ++L K++ ++++DL + + + +Q +LE +K+ E
Sbjct: 1922 EAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQ---ELEILKKEYDQEREE- 1977
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
K++Q +EDLE + + Q + E + E + E + L
Sbjct: 1978 -----KIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLE 2032
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL- 204
+ +E L + K D++ R E+ L+ E+ + AK+ +L+ +L+ +
Sbjct: 2033 SHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEM---TAKVRDLQTQLEELQKKYQ 2089
Query: 205 KSLEVSEEKANQRV 218
+ LE E N V
Sbjct: 2090 QKLEQEENPGNDNV 2103
Score = 40.7 bits (91), Expect = 0.006
Identities = 37/187 (19%), Positives = 89/187 (47%), Gaps = 15/187 (8%)
Query: 48 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 107
K L +++ + +N L++ + ++ ++Q T +E AL ++ + ++LEK ++
Sbjct: 279 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHM 338
Query: 108 TAQQKLLEAQQSAD------ENNRMCKVLENRAQ------QDEERMDQLTNQLKEARLLA 155
+ KL+ + A E ++ + E + Q EE + QL +++K+
Sbjct: 339 AEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQG 398
Query: 156 EDADGKSDEVSRKLAF--VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E+ + E S + AF +E L A+ ++ +E++E++K + + + +S ++
Sbjct: 399 EEL-REQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQ 457
Query: 214 ANQRVEE 220
RV++
Sbjct: 458 ELSRVKQ 464
Score = 40.3 bits (90), Expect = 0.007
Identities = 43/217 (19%), Positives = 97/217 (44%), Gaps = 13/217 (5%)
Query: 4 IKKKMQAMKLEKDNAMDKA---DTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ + + A+ L K+ +K + +Q D N++ + + + E + ++ + +
Sbjct: 1348 LSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQN-SISLSEKEAAISSLRKQYDEE 1406
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K +L +DL K T ++ +++AL +Q+++ K E AQ + + Q +
Sbjct: 1407 KCELLDQVQDLSFKVD--TLSKEKISAL----EQVDDWSNKFSEWKKKAQSRFTQHQNTV 1460
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
E ++ A + +E+++ L +L + + G+ ++ K+ E LE
Sbjct: 1461 KELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLET-- 1518
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 217
+KS A+I ELE+ + ++SL + NQ+
Sbjct: 1519 -ELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQ 1554
Score = 38.7 bits (86), Expect = 0.023
Identities = 38/216 (17%), Positives = 93/216 (43%), Gaps = 7/216 (3%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
+ ++++MK + ++ + + + +++ + A + + +L+K+L++ + L K +L
Sbjct: 1303 ENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEEL 1362
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
++ ++ KQLT + L + E++ S R ++K Q D +
Sbjct: 1363 KEKKVEISSLSKQLTDLNVQ---LQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSF 1419
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
++ L E++D +N+ E + A+ + ++L +LE+
Sbjct: 1420 KV-DTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQI---QLELKSKEAY 1475
Query: 185 SGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
D +I+ L+EEL L+ E ++E+
Sbjct: 1476 EKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEK 1511
Score = 38.3 bits (85), Expect = 0.030
Identities = 44/199 (22%), Positives = 86/199 (43%), Gaps = 23/199 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +K + MK E + MD+ QQ D+ ++ +V+ ++ +K L
Sbjct: 707 LSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS--IQRTEKAL---------- 754
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K+++ Q L+E++K L +A V+ +E D+++SE A KL Q
Sbjct: 755 KDQINQLELLLKERDKHLKEHQAH-------VENLEADIKRSEGELQQASAKLDVFQSYQ 807
Query: 121 DENNRMCKVLENR-AQQDEERMDQLTNQLKEARLLAEDADGKSD---EVSRKLAFVEDEL 176
+ K E + AQ ++ +D T ++ + +AE K D E+ V+D +
Sbjct: 808 SATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLM 867
Query: 177 EVAEDRVKSGDAKISELEE 195
+ E + + K+ L +
Sbjct: 868 QQLEKQNSEMEQKVKSLTQ 886
Score = 36.7 bits (81), Expect = 0.092
Identities = 38/212 (17%), Positives = 96/212 (45%), Gaps = 6/212 (2%)
Query: 4 IKKKMQAMKLEKDNAM-DKADTCEQQARDANLRA-EKVNEEVRELQKKLAQVEEDLILNK 61
++K + + EK+ + DK + + N + EK++ + EL+ +++ E ++ +
Sbjct: 642 MEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSE-VLKAR 700
Query: 62 NKLEQANKDLEEK-EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+KLE+ L+++ +K EA++ QQ + + K E S +K L+ Q
Sbjct: 701 HKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQ--I 758
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
++ + K + ++ + ++ L +K + + A K D + ++ + E
Sbjct: 759 NQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYE 818
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
+++ K+ +LE E ++ + +E ++
Sbjct: 819 EQLAQLQQKLLDLETERILLTKQVAEVEAQKK 850
Score = 36.7 bits (81), Expect = 0.092
Identities = 56/223 (25%), Positives = 103/223 (46%), Gaps = 23/223 (10%)
Query: 3 AIKKKMQAMK--LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++K +++ K LE N K+ E +A + L +E ++ EL++K Q + +
Sbjct: 1596 SMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESA-AKLAELKRKAEQ--KIAAIK 1652
Query: 61 KNKLEQANKDLEEKEKQLT-ATEAEVAALNRKVQQIEEDLEKSEER---SGTAQQKLLEA 116
K L Q +EEKE+Q TE+ ++ LN K+Q+ E ++ EE+ ++Q + L
Sbjct: 1653 KQLLSQ----MEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIV 1708
Query: 117 QQSADENNRMCKVLENRAQ-----QDEERMDQLTNQLKE-ARLLAEDADGKSDEVSRKLA 170
+SA + E +Q EE++ L L E +LL K + VS +
Sbjct: 1709 PRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVS---S 1765
Query: 171 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E + E +K A+ + E++ ++G+ + LE +K
Sbjct: 1766 HFEMRCQYQERLIKLEHAEAKQHEDQ-SMIGHLQEELEEKNKK 1807
Score = 36.3 bits (80), Expect = 0.12
Identities = 34/186 (18%), Positives = 90/186 (48%), Gaps = 2/186 (1%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK-EKQLTATEAEVAALNRKVQQI 95
E ++ E+ E+ K ++EE+L + K++ ++ ++LE K ++Q + +V ++ ++ +
Sbjct: 687 ESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS 746
Query: 96 EEDLEKS-EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 154
+ EK+ +++ + L E + E+ + LE ++ E + Q + +L +
Sbjct: 747 IQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSY 806
Query: 155 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
++ +LA ++ +L E +++E+E + K V L + ++ +
Sbjct: 807 QSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDL 866
Query: 215 NQRVEE 220
Q++E+
Sbjct: 867 MQQLEK 872
Score = 35.1 bits (77), Expect = 0.28
Identities = 57/287 (19%), Positives = 127/287 (44%), Gaps = 22/287 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED------ 56
++++++ +K E + M K+ EQ A+ L +++ + +EL KKL E +
Sbjct: 454 SLQQELSRVKQEVVDVMKKSSE-EQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMK 512
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV-QQIEEDLEKSEERSGTAQQKLLE 115
+ L K++ E K +EKE+Q + E+ + + + E L ++ + T + ++LE
Sbjct: 513 VALEKSQSEYL-KISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILE 571
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQL-KEARLLAEDADGKSDEVSRKL-AFVE 173
+ S +++ + K N+++ ++ N+ KE ++ E + + + + A
Sbjct: 572 LESSLEKSLQENK---NQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWT 628
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXX 233
++L+V + + ++ K+ E E+ K LK E+ + +EE
Sbjct: 629 EKLQVLKQQYQTEMEKLREKCEQEKET--LLKDKEIIFQA---HIEEMNEKTLEKLDVKQ 683
Query: 234 XXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
V K + +LE+EL + KD+ + E+++ E
Sbjct: 684 TELESLSSELSEVLKARH---KLEEELSVLKDQTDKMKQELEAKMDE 727
Score = 31.1 bits (67), Expect = 4.6
Identities = 47/278 (16%), Positives = 102/278 (36%), Gaps = 17/278 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+ ++ + + A + + E Q + E + E LQK+ ++ ++
Sbjct: 1281 LTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESC 1340
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ Q K+L E +T + E+ ++ + + L ++ Q S +
Sbjct: 1341 ITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLN----------VQLQNSISLS 1390
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
+ + R Q DEE+ +L +Q+++ L+ D S E L V+D +
Sbjct: 1391 EKEAAISSLRKQYDEEKC-ELLDQVQD---LSFKVDTLSKEKISALEQVDDWSNKFSEWK 1446
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXX 243
K ++ ++ + +K + LE+ ++A ++ E+
Sbjct: 1447 KKAQSRFTQHQNTVKEL---QIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEME 1503
Query: 244 KTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K++K+ LE EL R L D + E+
Sbjct: 1504 DDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEI 1541
>U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein.
Length = 2083
Score = 61.3 bits (142), Expect = 4e-09
Identities = 53/223 (23%), Positives = 111/223 (49%), Gaps = 14/223 (6%)
Query: 5 KKKMQAMKLEKDNAMDKADT-CEQQARDANLRAEKVN---EEVRELQKKLAQVEEDLILN 60
KKK Q+ + N + + E ++++A + E++N EE+ + K+ ++ ++ +
Sbjct: 1301 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDD 1360
Query: 61 KNKLEQANKDLEEKEKQLTAT----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
K+K+E+ +LE + K TA E + +++ + E L+ ++ ++L++
Sbjct: 1361 KSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQK 1420
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
Q E + + +NR ++ EE++ L NQ+ + E + + V+ + E+EL
Sbjct: 1421 LQHFQE---LGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEEL 1477
Query: 177 EVAEDRVKS-GDAKISELEE--ELKVVGNSLKSLEVSEEKANQ 216
+ EDR++S AK++EL+ E K+ + L EEK Q
Sbjct: 1478 KALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQ 1520
Score = 54.8 bits (126), Expect = 3e-07
Identities = 62/292 (21%), Positives = 128/292 (43%), Gaps = 21/292 (7%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQA---RDANLRAE-KVNEEVRELQKKLAQVEED--LI 58
K++ + EK+ ++ D Q+ +D ++ + K+ ++R+ + + Q+E+D ++
Sbjct: 161 KEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMV 220
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
+ + K Q ++ LE KE+++ + + + + +++ E EKSE + +K L Q
Sbjct: 221 IAETK-RQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQ 279
Query: 119 SADENNRMCKV-----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE--VSRKLAF 171
+E R K ++ + EE L +L + D KS E +++
Sbjct: 280 KTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKL 339
Query: 172 VEDELEVAEDRV-KSGDAKISELEEELKVVGNSLKS--LEVSEEKANQR---VEEFXXXX 225
E EL E + K + E +E++KV +S L++S+EK Q +EE
Sbjct: 340 HEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQK 399
Query: 226 XXXXXXXXXXXXXXXXXXKTVKKLQKEVD-RLEDELGINKDRYKSLADEMDS 276
+T + E++ LE L N+++ K LA +++
Sbjct: 400 KAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENENQSKDLAVHLEA 451
Score = 50.0 bits (114), Expect = 9e-06
Identities = 41/237 (17%), Positives = 109/237 (45%), Gaps = 8/237 (3%)
Query: 43 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 102
V EL+ +L Q+ E+ +QA LEEKE Q+ + +A++ +L + + ++++
Sbjct: 1126 VSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQ 1185
Query: 103 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
++ + + + + ++ EN +++ ++ + + L+ QL + + +++ S
Sbjct: 1186 QQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLS 1245
Query: 163 DE----VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
++ S + + E++ E+ D+V+ K+ L +E K+ ++L+ ++ K ++
Sbjct: 1246 EKEAAISSLRKQYDEEKCELL-DQVQDLSFKVDTLSKE-KI--SALEQVDDWSNKFSEWK 1301
Query: 219 EEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMD 275
++ K + ++++ L++EL R+ L EM+
Sbjct: 1302 KKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEME 1358
Score = 48.0 bits (109), Expect = 4e-05
Identities = 49/217 (22%), Positives = 99/217 (45%), Gaps = 12/217 (5%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
+K+ A LE A + A + +R + E++ E + E+ ++ ++ + + + + KL
Sbjct: 851 EKQFNAKMLEMAQA-NSAGISDAVSRLETNQKEQI-ESLTEVHRR--ELNDVISIWEKKL 906
Query: 65 EQANKDLEE-KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
Q ++L+E E QL E EVA L +K+ EK E K +Q N
Sbjct: 907 NQQAEELQEIHEIQLQEKEQEVAELKQKILLF--GCEKEEMNKEITWLKEEGVKQDTTLN 964
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
L+ + +Q ++ L + + E + ++ ++ F++++L +
Sbjct: 965 E-----LQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLA 1019
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ K+SEL +LK +SL+ S EK+N+ +E+
Sbjct: 1020 EEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLED 1056
Score = 43.6 bits (98), Expect = 8e-04
Identities = 38/226 (16%), Positives = 99/226 (43%), Gaps = 9/226 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K+K+ EK+ + +++ + ++ E++++ + + +D K
Sbjct: 931 LKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAH 990
Query: 64 LEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEEDLEKSEERSGTAQQKLLEA 116
LE+ DL + K+ T + ++ L RKV ++ L+ ++E + + ++
Sbjct: 991 LEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKS 1050
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL--LAEDADGKSDEVSRKLAFVED 174
+S ++ + K L + + T L EA+ L + K++ + +++ +
Sbjct: 1051 NKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQH 1110
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
++ + +SELE +L+ + +L +S ++A ++EE
Sbjct: 1111 RTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEE 1156
Score = 42.7 bits (96), Expect = 0.001
Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 22/218 (10%)
Query: 2 DAIKKKMQAMKLEKD-NAMDKADT-CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
D K K KLE D N K +T ++Q + + AE+ +V EL KL +E+
Sbjct: 983 DETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQS 1042
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
K+ E++NK LE+K + E+A Q++ +K+E LLEA+ +
Sbjct: 1043 LKSSHEKSNKSLEDKSLEFKKLSEELAI------QLDICCKKTE--------ALLEAKTN 1088
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
N K N T ++KEA L+ + + R+L ++ L ++
Sbjct: 1089 ELINISSSKT--NAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNIS 1146
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 217
+ ++ E E ++K + ++SL V+E++A Q+
Sbjct: 1147 ---FQQATHQLEEKENQIKSMKADIESL-VTEKEALQK 1180
Score = 42.7 bits (96), Expect = 0.001
Identities = 41/194 (21%), Positives = 82/194 (42%), Gaps = 13/194 (6%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E Q D + E ++L K++ ++++DL + + + +Q +LE +K+ E
Sbjct: 1777 EAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQ---ELEILKKEYDQEREE- 1832
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
K++Q +EDLE + + Q + E + E + E + L
Sbjct: 1833 -----KIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLE 1887
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL- 204
+ +E L + K D++ R E+ L+ E+ + AK+ +L+ +L+ +
Sbjct: 1888 SHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEM---TAKVRDLQTQLEELQKKYQ 1944
Query: 205 KSLEVSEEKANQRV 218
+ LE E N V
Sbjct: 1945 QKLEQEENPGNDNV 1958
Score = 40.7 bits (91), Expect = 0.006
Identities = 37/187 (19%), Positives = 89/187 (47%), Gaps = 15/187 (8%)
Query: 48 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 107
K L +++ + +N L++ + ++ ++Q T +E AL ++ + ++LEK ++
Sbjct: 134 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHM 193
Query: 108 TAQQKLLEAQQSAD------ENNRMCKVLENRAQ------QDEERMDQLTNQLKEARLLA 155
+ KL+ + A E ++ + E + Q EE + QL +++K+
Sbjct: 194 AEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQG 253
Query: 156 EDADGKSDEVSRKLAF--VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E+ + E S + AF +E L A+ ++ +E++E++K + + + +S ++
Sbjct: 254 EEL-REQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQ 312
Query: 214 ANQRVEE 220
RV++
Sbjct: 313 ELSRVKQ 319
Score = 40.3 bits (90), Expect = 0.007
Identities = 43/217 (19%), Positives = 97/217 (44%), Gaps = 13/217 (5%)
Query: 4 IKKKMQAMKLEKDNAMDKA---DTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ + + A+ L K+ +K + +Q D N++ + + + E + ++ + +
Sbjct: 1203 LSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQN-SISLSEKEAAISSLRKQYDEE 1261
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K +L +DL K T ++ +++AL +Q+++ K E AQ + + Q +
Sbjct: 1262 KCELLDQVQDLSFKVD--TLSKEKISAL----EQVDDWSNKFSEWKKKAQSRFTQHQNTV 1315
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
E ++ A + +E+++ L +L + + G+ ++ K+ E LE
Sbjct: 1316 KELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLET-- 1373
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 217
+KS A+I ELE+ + ++SL + NQ+
Sbjct: 1374 -ELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQ 1409
Score = 38.7 bits (86), Expect = 0.023
Identities = 38/216 (17%), Positives = 93/216 (43%), Gaps = 7/216 (3%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
+ ++++MK + ++ + + + +++ + A + + +L+K+L++ + L K +L
Sbjct: 1158 ENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEEL 1217
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
++ ++ KQLT + L + E++ S R ++K Q D +
Sbjct: 1218 KEKKVEISSLSKQLTDLNVQ---LQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSF 1274
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
++ L E++D +N+ E + A+ + ++L +LE+
Sbjct: 1275 KV-DTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQI---QLELKSKEAY 1330
Query: 185 SGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
D +I+ L+EEL L+ E ++E+
Sbjct: 1331 EKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEK 1366
Score = 38.3 bits (85), Expect = 0.030
Identities = 44/199 (22%), Positives = 86/199 (43%), Gaps = 23/199 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +K + MK E + MD+ QQ D+ ++ +V+ ++ +K L
Sbjct: 562 LSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS--IQRTEKAL---------- 609
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K+++ Q L+E++K L +A V+ +E D+++SE A KL Q
Sbjct: 610 KDQINQLELLLKERDKHLKEHQAH-------VENLEADIKRSEGELQQASAKLDVFQSYQ 662
Query: 121 DENNRMCKVLENR-AQQDEERMDQLTNQLKEARLLAEDADGKSD---EVSRKLAFVEDEL 176
+ K E + AQ ++ +D T ++ + +AE K D E+ V+D +
Sbjct: 663 SATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLM 722
Query: 177 EVAEDRVKSGDAKISELEE 195
+ E + + K+ L +
Sbjct: 723 QQLEKQNSEMEQKVKSLTQ 741
Score = 37.5 bits (83), Expect = 0.053
Identities = 58/287 (20%), Positives = 127/287 (44%), Gaps = 22/287 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED------ 56
++++++ +K E + M K+ EQ A+ L +++ + +EL KKL E +
Sbjct: 309 SLQQELSRVKQEVVDVMKKSSE-EQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMK 367
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV-QQIEEDLEKSEERSGTAQQKLLE 115
+ L K++ E K +EKE+Q + E+ + + + E L ++ + T + ++LE
Sbjct: 368 VALEKSQSEYL-KISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILE 426
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQL-KEARLLAEDADGKSDEVSRKL-AFVE 173
+ S +++ + EN+++ ++ N+ KE ++ E + + + + A
Sbjct: 427 LESSLEKS---LQENENQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWA 483
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXX 233
+EL+V + + ++ K+ E E+ K LK E+ + +EE
Sbjct: 484 EELQVLKQQYQTEMEKLREKCEQEKET--LLKDKEIIFQA---HIEEMNEKTLEKLDVNQ 538
Query: 234 XXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
V K + +LE+EL + KD+ + E+++ E
Sbjct: 539 TELESLSSELSEVLKARH---KLEEELSVLKDQTDKMKQELEAKMDE 582
Score = 36.7 bits (81), Expect = 0.092
Identities = 56/223 (25%), Positives = 103/223 (46%), Gaps = 23/223 (10%)
Query: 3 AIKKKMQAMK--LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++K +++ K LE N K+ E +A + L +E ++ EL++K Q + +
Sbjct: 1451 SMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESA-AKLAELKRKAEQ--KIAAIK 1507
Query: 61 KNKLEQANKDLEEKEKQLT-ATEAEVAALNRKVQQIEEDLEKSEER---SGTAQQKLLEA 116
K L Q +EEKE+Q TE+ ++ LN K+Q+ E ++ EE+ ++Q + L
Sbjct: 1508 KQLLSQ----MEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIV 1563
Query: 117 QQSADENNRMCKVLENRAQ-----QDEERMDQLTNQLKE-ARLLAEDADGKSDEVSRKLA 170
+SA + E +Q EE++ L L E +LL K + VS +
Sbjct: 1564 PRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVS---S 1620
Query: 171 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E + E +K A+ + E++ ++G+ + LE +K
Sbjct: 1621 HFEMRCQYQERLIKLEHAEAKQHEDQ-SMIGHLQEELEEKNKK 1662
Score = 36.3 bits (80), Expect = 0.12
Identities = 38/212 (17%), Positives = 95/212 (44%), Gaps = 6/212 (2%)
Query: 4 IKKKMQAMKLEKDNAM-DKADTCEQQARDANLRA-EKVNEEVRELQKKLAQVEEDLILNK 61
++K + + EK+ + DK + + N + EK++ EL+ +++ E ++ +
Sbjct: 497 MEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVNQTELESLSSELSE-VLKAR 555
Query: 62 NKLEQANKDLEEK-EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+KLE+ L+++ +K EA++ QQ + + K E S +K L+ Q
Sbjct: 556 HKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQ--I 613
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
++ + K + ++ + ++ L +K + + A K D + ++ + E
Sbjct: 614 NQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYE 673
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
+++ K+ +LE E ++ + +E ++
Sbjct: 674 EQLAQLQQKLLDLETERILLTKQVAEVEAQKK 705
Score = 36.3 bits (80), Expect = 0.12
Identities = 34/186 (18%), Positives = 90/186 (48%), Gaps = 2/186 (1%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK-EKQLTATEAEVAALNRKVQQI 95
E ++ E+ E+ K ++EE+L + K++ ++ ++LE K ++Q + +V ++ ++ +
Sbjct: 542 ESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS 601
Query: 96 EEDLEKS-EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 154
+ EK+ +++ + L E + E+ + LE ++ E + Q + +L +
Sbjct: 602 IQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSY 661
Query: 155 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
++ +LA ++ +L E +++E+E + K V L + ++ +
Sbjct: 662 QSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDL 721
Query: 215 NQRVEE 220
Q++E+
Sbjct: 722 MQQLEK 727
Score = 31.1 bits (67), Expect = 4.6
Identities = 47/278 (16%), Positives = 102/278 (36%), Gaps = 17/278 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+ ++ + + A + + E Q + E + E LQK+ ++ ++
Sbjct: 1136 LTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESC 1195
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ Q K+L E +T + E+ ++ + + L ++ Q S +
Sbjct: 1196 ITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLN----------VQLQNSISLS 1245
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
+ + R Q DEE+ +L +Q+++ L+ D S E L V+D +
Sbjct: 1246 EKEAAISSLRKQYDEEKC-ELLDQVQD---LSFKVDTLSKEKISALEQVDDWSNKFSEWK 1301
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXX 243
K ++ ++ + +K + LE+ ++A ++ E+
Sbjct: 1302 KKAQSRFTQHQNTVKEL---QIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEME 1358
Query: 244 KTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K++K+ LE EL R L D + E+
Sbjct: 1359 DDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEI 1396
>DQ139275-1|ABA43896.1| 1313|Homo sapiens Tax1-binding protein 2
protein.
Length = 1313
Score = 61.3 bits (142), Expect = 4e-09
Identities = 44/190 (23%), Positives = 91/190 (47%), Gaps = 2/190 (1%)
Query: 20 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 79
D+ D+ ++Q D+ ++A + V L LA+VEE ++K+ + L + L
Sbjct: 987 DRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLN 1046
Query: 80 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 139
+T + L + + E D + +ER A+Q L EA++ + + L E
Sbjct: 1047 STRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLEL 1106
Query: 140 RMDQLTNQLKEAR-LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 198
+ + QL++ R +L + +G++ ++ + ++DE + ++R+ S +++LE E +
Sbjct: 1107 QRVEAEGQLQQLREVLRQRQEGEAAALN-TVQKLQDERRLLQERLGSLQRALAQLEAEKR 1165
Query: 199 VVGNSLKSLE 208
V S LE
Sbjct: 1166 EVERSALRLE 1175
Score = 55.2 bits (127), Expect = 2e-07
Identities = 48/197 (24%), Positives = 97/197 (49%), Gaps = 17/197 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++K + A + ++ ++ D Q +A ++ + E+V+ L+ ++A +E + + +
Sbjct: 1055 LQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQ 1114
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L+Q + L +++ E E AALN VQ+++++ +ER G+ Q+ L + + E
Sbjct: 1115 LQQLREVLRQRQ------EGEAAALN-TVQKLQDERRLLQERLGSLQRALAQLEAEKREV 1167
Query: 124 NRMCKVLEN-----RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
R LE R D+ ++L + RL AE G+ D R L E EL
Sbjct: 1168 ERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAE--KGRLD---RTLTGAELELAE 1222
Query: 179 AEDRVKSGDAKISELEE 195
A+ +++ +A++ LE+
Sbjct: 1223 AQRQIQQLEAQVVVLEQ 1239
Score = 53.6 bits (123), Expect = 8e-07
Identities = 53/223 (23%), Positives = 105/223 (47%), Gaps = 20/223 (8%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 65
+++++ + E+D + +Q + + R+LQK +A+ EE +L
Sbjct: 819 QELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLS 878
Query: 66 --QANKDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
QA L+E+ E++ AT +VA L R +Q E +L S+E+ ++ K E +
Sbjct: 879 GVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEK--ISKMKANETKL 936
Query: 119 SADENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
D+ R+ +VL E+R + E + L +L+ +RL G SD ++ A ++D
Sbjct: 937 EGDK-RRLKEVLDASESRTVKLELQRRSLEGELQRSRL------GLSDREAQAQA-LQDR 988
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
++ + +V + K L+ ++ + +L +E SE +V
Sbjct: 989 VDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKV 1031
Score = 46.4 bits (105), Expect = 1e-04
Identities = 43/196 (21%), Positives = 90/196 (45%), Gaps = 14/196 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A+ +++ M+ E+D+A +A ++ ++ V+ + +Q +LA EE + ++
Sbjct: 837 ALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSER 896
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQI---EEDLEKSEER------SGTAQQKL 113
+ + E+ L ATE+E+ A K+ ++ E LE + R + ++
Sbjct: 897 ERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVK 956
Query: 114 LEAQQSADENNRMCKVL-----ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
LE Q+ + E L E +AQ ++R+D L Q+ ++ + A + ++
Sbjct: 957 LELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGA 1016
Query: 169 LAFVEDELEVAEDRVK 184
LA VE+ D+V+
Sbjct: 1017 LAKVEESEGALRDKVR 1032
Score = 45.2 bits (102), Expect = 3e-04
Identities = 52/230 (22%), Positives = 107/230 (46%), Gaps = 18/230 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQA-RDANLRAEKVNEEV--RELQKKLAQVEEDLIL 59
++ K++ A KL + +A EQ+A + +L+ + +E REL+ + AQ++ L
Sbjct: 266 SLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQR 325
Query: 60 NKNKL-EQANKDLEEKEKQLTATEAEV-AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
+ +L + + EE +++ A + E L + ++ L E +KL+ +
Sbjct: 326 EQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTR 385
Query: 118 QSAD----ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
S E R + ++R +QD ++ LT++L++ R E+A + R+L
Sbjct: 386 HSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQ--- 442
Query: 174 DELEVAEDRVKSGDAKISELEE---ELKVVGNSLKSLEVSEEKANQRVEE 220
E A D K D+ + E EE +L+++ ++ L +A +++ E
Sbjct: 443 ---EQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRE 489
Score = 44.4 bits (100), Expect = 5e-04
Identities = 52/221 (23%), Positives = 97/221 (43%), Gaps = 21/221 (9%)
Query: 8 MQAMKLEKDNAMDKADT--CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 65
+QA K E A+ KA+ E + LRAE+ + +++ KL+ + E L +K L
Sbjct: 2 LQAEKAEVAEALTKAEAGRVELELSMTKLRAEEAS--LQDSLSKLSALNESLAQDKLDLN 59
Query: 66 QANKDLEEKEKQLTA----TEAEVAALNRKVQQIEE-DLEKSEERSGTAQQKLLEAQQSA 120
+ LEE++ L E E + +++EE LE+ R G + L A+Q+
Sbjct: 60 RLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQG-LEGSLRVAEQAQ 118
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ + L + Q +E++ QL+ QL G+ E+ + + ++E E
Sbjct: 119 EALEQQLPTLRHERSQLQEQLAQLSRQL----------SGREQELEQARREAQRQVEALE 168
Query: 181 DRVKSGDAKISE-LEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ +A E +++V + +SEE R+E+
Sbjct: 169 RAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEK 209
Score = 43.6 bits (98), Expect = 8e-04
Identities = 45/199 (22%), Positives = 88/199 (44%), Gaps = 11/199 (5%)
Query: 26 EQQARDANLRAEK----VNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT 81
E+Q RDA R E+ VN EL+ AQ EE + ++ + + + KQ +
Sbjct: 396 ERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSC 455
Query: 82 EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
E L +++ +E+ + AQ+KL E+Q+ + + L + +
Sbjct: 456 LREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKER 515
Query: 142 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 201
+ L +E R + A+ S+ +S KLA + E ++A ++ + + EL+
Sbjct: 516 EALRRSNEELRSAVKKAE--SERISLKLANEDKEQKLA--LLEEARTAVGKEAGELR--- 568
Query: 202 NSLKSLEVSEEKANQRVEE 220
L+ +E S +A + ++E
Sbjct: 569 TGLQEVERSRLEARRELQE 587
Score = 41.1 bits (92), Expect = 0.004
Identities = 40/219 (18%), Positives = 102/219 (46%), Gaps = 10/219 (4%)
Query: 5 KKKMQAMKLEKDNA---MDKADTCEQQARDA-NLRAEKVNEEVRELQKKLAQVEEDLILN 60
+++++ ++LE++ A ++ + +QA++A + + E +LQ++LAQ+ L
Sbjct: 90 QERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGR 149
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +LEQA ++ + + + L E AL ++ + L +E T ++ +
Sbjct: 150 EQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEK 209
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ ++ + Q E R +QL + + L E G+ + +++ +++ + +
Sbjct: 210 EALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDK 269
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ + K+ + E E + SL+ + E+ QR++
Sbjct: 270 ELMAQ---KLVQAEREAQA---SLREQRAAHEEDLQRLQ 302
Score = 39.5 bits (88), Expect = 0.013
Identities = 42/245 (17%), Positives = 100/245 (40%), Gaps = 4/245 (1%)
Query: 14 EKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 72
E + A+ DK + ++ ++ LQK L E D + + +L+ A + L
Sbjct: 1022 ESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALS 1081
Query: 73 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 132
E KQ ++ +V L +V +E ++E + ++ L + Q+ + L++
Sbjct: 1082 EARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQD 1141
Query: 133 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE-VAEDRVKSGDAKIS 191
+ +ER+ L L + + + + + + + L+ V ++++S + +
Sbjct: 1142 ERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTV- 1200
Query: 192 ELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQK 251
L E + +L E+ +A +++++ + + +LQ+
Sbjct: 1201 RLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQL-ELQQ 1259
Query: 252 EVDRL 256
EV+RL
Sbjct: 1260 EVERL 1264
Score = 37.9 bits (84), Expect = 0.040
Identities = 52/227 (22%), Positives = 106/227 (46%), Gaps = 19/227 (8%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+A+ K+ + ++ A + T ++A L E + + E+Q++LAQ+E +
Sbjct: 175 EALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLE----ARR 230
Query: 62 NKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIEEDL-EKSEERSGTAQQKLLEA 116
+LE + L E +L ++ A K +E + +K + AQ L E
Sbjct: 231 EQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQ 290
Query: 117 QQSADEN-NRMCKVLENRAQQDEERMDQLTNQL-KEARLLAEDADGKSDEVSRKLAFVED 174
+ + +E+ R+ + E ++ E QL +QL +E L + + +E+S ++A ++
Sbjct: 291 RAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQ 350
Query: 175 E----LEVAE-DRVKSGDAKISE---LEEELKVVGNSLKSLEVSEEK 213
E L +AE ++ ++ K SE L E+L +SL ++ + E+
Sbjct: 351 ERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMER 397
Score = 37.1 bits (82), Expect = 0.070
Identities = 28/119 (23%), Positives = 56/119 (47%), Gaps = 5/119 (4%)
Query: 38 KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 97
++ E RE+++ ++E+D + + L++ ++ + AE L+R + E
Sbjct: 1159 QLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAEL 1218
Query: 98 DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
+L +++ + QQ LEAQ E + LE AQQ + + Q +L+ A+ E
Sbjct: 1219 ELAEAQRQ---IQQ--LEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTE 1272
Score = 36.3 bits (80), Expect = 0.12
Identities = 44/217 (20%), Positives = 97/217 (44%), Gaps = 19/217 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++ + ++++ A + + + A++ + NEE+R KK E + I
Sbjct: 487 LRESQEGREVQRQEAGELRRSLGEGAKEREA-LRRSNEELRSAVKK---AESERI----S 538
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L+ AN+D KE++L E A+ ++ ++ L++ E + LEA++ E
Sbjct: 539 LKLANED---KEQKLALLEEARTAVGKEAGELRTGLQEVE-------RSRLEARRELQEL 588
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
R K+L++ + + +L +L +++ ++ + ++L E LEV +
Sbjct: 589 RRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQEL 648
Query: 184 KSGDAKISELEEELKV-VGNSLKSLEVSEEKANQRVE 219
+ K+ E E E + L SLE + Q+++
Sbjct: 649 QVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLD 685
Score = 36.3 bits (80), Expect = 0.12
Identities = 31/166 (18%), Positives = 69/166 (41%), Gaps = 4/166 (2%)
Query: 47 QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS 106
++KLA +EE + + L+E E+ E+ L R+++ ++ + +
Sbjct: 547 EQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGREL 606
Query: 107 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 166
Q +L +++ E+ R L R + E ++ + +L+ A+ ++ +G+
Sbjct: 607 AELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRE 666
Query: 167 RKLAFVEDELEVAE----DRVKSGDAKISELEEELKVVGNSLKSLE 208
R+L +E E D + + K+ E +G L + E
Sbjct: 667 RRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAE 712
>BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet coiled-coil,
rootletin protein.
Length = 1898
Score = 61.3 bits (142), Expect = 4e-09
Identities = 44/190 (23%), Positives = 91/190 (47%), Gaps = 2/190 (1%)
Query: 20 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 79
D+ D+ ++Q D+ ++A + V L LA+VEE ++K+ + L + L
Sbjct: 1565 DRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLN 1624
Query: 80 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 139
+T + L + + E D + +ER A+Q L EA++ + + L E
Sbjct: 1625 STRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLEL 1684
Query: 140 RMDQLTNQLKEAR-LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 198
+ + QL++ R +L + +G++ ++ + ++DE + ++R+ S +++LE E +
Sbjct: 1685 QRVEAEGQLQQLREVLRQRQEGEAAALN-TVQKLQDERRLLQERLGSLQRALAQLEAEKR 1743
Query: 199 VVGNSLKSLE 208
V S LE
Sbjct: 1744 EVERSALRLE 1753
Score = 55.6 bits (128), Expect = 2e-07
Identities = 58/263 (22%), Positives = 121/263 (46%), Gaps = 23/263 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++K + A + ++ ++ D Q +A ++ + E+V+ L+ ++A +E + + +
Sbjct: 1633 LQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQ 1692
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L+Q + L +++ E E AALN VQ+++++ +ER G+ Q+ L + + E
Sbjct: 1693 LQQLREVLRQRQ------EGEAAALN-TVQKLQDERRLLQERLGSLQRALAQLEAEKREV 1745
Query: 124 NRMCKVLEN-----RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
R LE R D+ ++L + RL AE G+ D R L E EL
Sbjct: 1746 ERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAE--KGRLD---RTLTGAELELAE 1800
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEV-SEEKANQRVEEFXXXXXXXXXXXXXXXX 237
A+ +++ +A++ LE+ +S LEV ++++ + +E
Sbjct: 1801 AQRQIQQLEAQVVVLEQ-----SHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEA 1855
Query: 238 XXXXXXKTVKKLQKEVDRLEDEL 260
+ V+ L+++V L+ +L
Sbjct: 1856 RERAHRQRVRGLEEQVSTLKGQL 1878
Score = 53.6 bits (123), Expect = 8e-07
Identities = 53/223 (23%), Positives = 105/223 (47%), Gaps = 20/223 (8%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 65
+++++ + E+D + +Q + + R+LQK +A+ EE +L
Sbjct: 1397 QELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLS 1456
Query: 66 --QANKDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
QA L+E+ E++ AT +VA L R +Q E +L S+E+ ++ K E +
Sbjct: 1457 GVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEK--ISKMKANETKL 1514
Query: 119 SADENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
D+ R+ +VL E+R + E + L +L+ +RL G SD ++ A ++D
Sbjct: 1515 EGDK-RRLKEVLDASESRTVKLELQRRSLEGELQRSRL------GLSDREAQAQA-LQDR 1566
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
++ + +V + K L+ ++ + +L +E SE +V
Sbjct: 1567 VDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKV 1609
Score = 49.6 bits (113), Expect = 1e-05
Identities = 41/216 (18%), Positives = 91/216 (42%), Gaps = 4/216 (1%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ + + EK N +QQA + EK+ EL+++ ++EE+
Sbjct: 475 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 534
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ ++LE +QL E + + L +++ ++ E L ++ + Q + E ++ +
Sbjct: 535 GARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKA 594
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
LE + L + L + L E +++R +A +E+E + R
Sbjct: 595 EAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQ 654
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ + + + EE + L+ L + +E A Q +E
Sbjct: 655 RQAEQEATVAREEQE----RLEELRLEQEVARQGLE 686
Score = 47.2 bits (107), Expect = 7e-05
Identities = 52/218 (23%), Positives = 94/218 (43%), Gaps = 9/218 (4%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL---AQVEEDLILNKNK 63
++Q M+ + + D T +Q D+ + E+++ L+ K Q ED +
Sbjct: 415 QVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQR 474
Query: 64 LEQANKDLEEKEKQLTATEAEVAALN-RKVQQIEEDLEKSEERSGTAQQKLLEAQQSA-D 121
L AN +L +EK A +VA +++Q E L+ ++E + +L E Q+ A
Sbjct: 475 LRSAN-ELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQ 533
Query: 122 ENNRMCKVLE---NRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
+ R+ + LE + +Q E + L +L E R A + D + + A V + L
Sbjct: 534 DGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTK 593
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
AE + +++L E + +SL L E Q
Sbjct: 594 AEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQ 631
Score = 46.4 bits (105), Expect = 1e-04
Identities = 43/196 (21%), Positives = 90/196 (45%), Gaps = 14/196 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A+ +++ M+ E+D+A +A ++ ++ V+ + +Q +LA EE + ++
Sbjct: 1415 ALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSER 1474
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQI---EEDLEKSEER------SGTAQQKL 113
+ + E+ L ATE+E+ A K+ ++ E LE + R + ++
Sbjct: 1475 ERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVK 1534
Query: 114 LEAQQSADENNRMCKVL-----ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
LE Q+ + E L E +AQ ++R+D L Q+ ++ + A + ++
Sbjct: 1535 LELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGA 1594
Query: 169 LAFVEDELEVAEDRVK 184
LA VE+ D+V+
Sbjct: 1595 LAKVEESEGALRDKVR 1610
Score = 45.2 bits (102), Expect = 3e-04
Identities = 52/230 (22%), Positives = 107/230 (46%), Gaps = 18/230 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQA-RDANLRAEKVNEEV--RELQKKLAQVEEDLIL 59
++ K++ A KL + +A EQ+A + +L+ + +E REL+ + AQ++ L
Sbjct: 844 SLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQR 903
Query: 60 NKNKL-EQANKDLEEKEKQLTATEAEV-AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
+ +L + + EE +++ A + E L + ++ L E +KL+ +
Sbjct: 904 EQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTR 963
Query: 118 QSAD----ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
S E R + ++R +QD ++ LT++L++ R E+A + R+L
Sbjct: 964 HSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQ--- 1020
Query: 174 DELEVAEDRVKSGDAKISELEE---ELKVVGNSLKSLEVSEEKANQRVEE 220
E A D K D+ + E EE +L+++ ++ L +A +++ E
Sbjct: 1021 ---EQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRE 1067
Score = 44.4 bits (100), Expect = 5e-04
Identities = 52/221 (23%), Positives = 97/221 (43%), Gaps = 21/221 (9%)
Query: 8 MQAMKLEKDNAMDKADT--CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 65
+QA K E A+ KA+ E + LRAE+ + +++ KL+ + E L +K L
Sbjct: 580 LQAEKAEVAEALTKAEAGRVELELSMTKLRAEEAS--LQDSLSKLSALNESLAQDKLDLN 637
Query: 66 QANKDLEEKEKQLTA----TEAEVAALNRKVQQIEE-DLEKSEERSGTAQQKLLEAQQSA 120
+ LEE++ L E E + +++EE LE+ R G + L A+Q+
Sbjct: 638 RLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQG-LEGSLRVAEQAQ 696
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ + L + Q +E++ QL+ QL G+ E+ + + ++E E
Sbjct: 697 EALEQQLPTLRHERSQLQEQLAQLSRQL----------SGREQELEQARREAQRQVEALE 746
Query: 181 DRVKSGDAKISE-LEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ +A E +++V + +SEE R+E+
Sbjct: 747 RAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEK 787
Score = 43.6 bits (98), Expect = 8e-04
Identities = 45/199 (22%), Positives = 88/199 (44%), Gaps = 11/199 (5%)
Query: 26 EQQARDANLRAEK----VNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT 81
E+Q RDA R E+ VN EL+ AQ EE + ++ + + + KQ +
Sbjct: 974 ERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSC 1033
Query: 82 EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
E L +++ +E+ + AQ+KL E+Q+ + + L + +
Sbjct: 1034 LREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKER 1093
Query: 142 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 201
+ L +E R + A+ S+ +S KLA + E ++A ++ + + EL+
Sbjct: 1094 EALRRSNEELRSAVKKAE--SERISLKLANEDKEQKLA--LLEEARTAVGKEAGELR--- 1146
Query: 202 NSLKSLEVSEEKANQRVEE 220
L+ +E S +A + ++E
Sbjct: 1147 TGLQEVERSRLEARRELQE 1165
Score = 41.1 bits (92), Expect = 0.004
Identities = 40/219 (18%), Positives = 102/219 (46%), Gaps = 10/219 (4%)
Query: 5 KKKMQAMKLEKDNA---MDKADTCEQQARDA-NLRAEKVNEEVRELQKKLAQVEEDLILN 60
+++++ ++LE++ A ++ + +QA++A + + E +LQ++LAQ+ L
Sbjct: 668 QERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGR 727
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +LEQA ++ + + + L E AL ++ + L +E T ++ +
Sbjct: 728 EQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEK 787
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ ++ + Q E R +QL + + L E G+ + +++ +++ + +
Sbjct: 788 EALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDK 847
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ + K+ + E E + SL+ + E+ QR++
Sbjct: 848 ELMAQ---KLVQAEREAQA---SLREQRAAHEEDLQRLQ 880
Score = 40.7 bits (91), Expect = 0.006
Identities = 42/210 (20%), Positives = 88/210 (41%), Gaps = 13/210 (6%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+ ++++ + ++ ++ + D E++ DA +V E+ ++L Q+E +
Sbjct: 501 EELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLA 560
Query: 62 NKLEQANKDLEEKEKQ---LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
+L + + L Q L A +AEVA K + +LE S KL +
Sbjct: 561 KELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELS-------MTKLRAEEA 613
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
S ++ L QD+ +++L QL+E + + G+ + ++ +E E
Sbjct: 614 SLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQ---GRQRQAEQEATVAREEQER 670
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLE 208
E+ + LE L+V + ++LE
Sbjct: 671 LEELRLEQEVARQGLEGSLRVAEQAQEALE 700
Score = 39.5 bits (88), Expect = 0.013
Identities = 42/245 (17%), Positives = 100/245 (40%), Gaps = 4/245 (1%)
Query: 14 EKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 72
E + A+ DK + ++ ++ LQK L E D + + +L+ A + L
Sbjct: 1600 ESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALS 1659
Query: 73 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 132
E KQ ++ +V L +V +E ++E + ++ L + Q+ + L++
Sbjct: 1660 EARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQD 1719
Query: 133 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE-VAEDRVKSGDAKIS 191
+ +ER+ L L + + + + + + + L+ V ++++S + +
Sbjct: 1720 ERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTV- 1778
Query: 192 ELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQK 251
L E + +L E+ +A +++++ + + +LQ+
Sbjct: 1779 RLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQL-ELQQ 1837
Query: 252 EVDRL 256
EV+RL
Sbjct: 1838 EVERL 1842
Score = 37.9 bits (84), Expect = 0.040
Identities = 52/227 (22%), Positives = 106/227 (46%), Gaps = 19/227 (8%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+A+ K+ + ++ A + T ++A L E + + E+Q++LAQ+E +
Sbjct: 753 EALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLE----ARR 808
Query: 62 NKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIEEDL-EKSEERSGTAQQKLLEA 116
+LE + L E +L ++ A K +E + +K + AQ L E
Sbjct: 809 EQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQ 868
Query: 117 QQSADEN-NRMCKVLENRAQQDEERMDQLTNQL-KEARLLAEDADGKSDEVSRKLAFVED 174
+ + +E+ R+ + E ++ E QL +QL +E L + + +E+S ++A ++
Sbjct: 869 RAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQ 928
Query: 175 E----LEVAE-DRVKSGDAKISE---LEEELKVVGNSLKSLEVSEEK 213
E L +AE ++ ++ K SE L E+L +SL ++ + E+
Sbjct: 929 ERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMER 975
Score = 37.5 bits (83), Expect = 0.053
Identities = 38/166 (22%), Positives = 82/166 (49%), Gaps = 11/166 (6%)
Query: 46 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 105
L K+ QV++ + + E + L KQL+ +E+E AL ++Q++ + + + +
Sbjct: 409 LHKRQLQVQD----MRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQA 464
Query: 106 SGTAQ---QKLLEAQQ--SADENN--RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA 158
AQ Q+L A + S +++N +V + +A++ + ++L +E R +
Sbjct: 465 HEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRL 524
Query: 159 DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL 204
+ + ++ + A V ELE + +++ + K S L +EL V +L
Sbjct: 525 EEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREAL 570
Score = 36.3 bits (80), Expect = 0.12
Identities = 44/217 (20%), Positives = 97/217 (44%), Gaps = 19/217 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++ + ++++ A + + + A++ + NEE+R KK E + I
Sbjct: 1065 LRESQEGREVQRQEAGELRRSLGEGAKEREA-LRRSNEELRSAVKK---AESERI----S 1116
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L+ AN+D KE++L E A+ ++ ++ L++ E + LEA++ E
Sbjct: 1117 LKLANED---KEQKLALLEEARTAVGKEAGELRTGLQEVE-------RSRLEARRELQEL 1166
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
R K+L++ + + +L +L +++ ++ + ++L E LEV +
Sbjct: 1167 RRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQEL 1226
Query: 184 KSGDAKISELEEELKV-VGNSLKSLEVSEEKANQRVE 219
+ K+ E E E + L SLE + Q+++
Sbjct: 1227 QVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLD 1263
Score = 36.3 bits (80), Expect = 0.12
Identities = 31/166 (18%), Positives = 69/166 (41%), Gaps = 4/166 (2%)
Query: 47 QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS 106
++KLA +EE + + L+E E+ E+ L R+++ ++ + +
Sbjct: 1125 EQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGREL 1184
Query: 107 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 166
Q +L +++ E+ R L R + E ++ + +L+ A+ ++ +G+
Sbjct: 1185 AELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRE 1244
Query: 167 RKLAFVEDELEVAE----DRVKSGDAKISELEEELKVVGNSLKSLE 208
R+L +E E D + + K+ E +G L + E
Sbjct: 1245 RRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAE 1290
>BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet coiled-coil,
rootletin protein.
Length = 2017
Score = 61.3 bits (142), Expect = 4e-09
Identities = 44/190 (23%), Positives = 91/190 (47%), Gaps = 2/190 (1%)
Query: 20 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 79
D+ D+ ++Q D+ ++A + V L LA+VEE ++K+ + L + L
Sbjct: 1684 DRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLN 1743
Query: 80 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 139
+T + L + + E D + +ER A+Q L EA++ + + L E
Sbjct: 1744 STRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLEL 1803
Query: 140 RMDQLTNQLKEAR-LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 198
+ + QL++ R +L + +G++ ++ + ++DE + ++R+ S +++LE E +
Sbjct: 1804 QRVEAEGQLQQLREVLRQRQEGEAAALN-TVQKLQDERRLLQERLGSLQRALAQLEAEKR 1862
Query: 199 VVGNSLKSLE 208
V S LE
Sbjct: 1863 EVERSALRLE 1872
Score = 55.6 bits (128), Expect = 2e-07
Identities = 58/263 (22%), Positives = 121/263 (46%), Gaps = 23/263 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++K + A + ++ ++ D Q +A ++ + E+V+ L+ ++A +E + + +
Sbjct: 1752 LQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQ 1811
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L+Q + L +++ E E AALN VQ+++++ +ER G+ Q+ L + + E
Sbjct: 1812 LQQLREVLRQRQ------EGEAAALN-TVQKLQDERRLLQERLGSLQRALAQLEAEKREV 1864
Query: 124 NRMCKVLEN-----RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
R LE R D+ ++L + RL AE G+ D R L E EL
Sbjct: 1865 ERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAE--KGRLD---RTLTGAELELAE 1919
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEV-SEEKANQRVEEFXXXXXXXXXXXXXXXX 237
A+ +++ +A++ LE+ +S LEV ++++ + +E
Sbjct: 1920 AQRQIQQLEAQVVVLEQ-----SHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEA 1974
Query: 238 XXXXXXKTVKKLQKEVDRLEDEL 260
+ V+ L+++V L+ +L
Sbjct: 1975 RERAHRQRVRGLEEQVSTLKGQL 1997
Score = 53.6 bits (123), Expect = 8e-07
Identities = 53/223 (23%), Positives = 105/223 (47%), Gaps = 20/223 (8%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 65
+++++ + E+D + +Q + + R+LQK +A+ EE +L
Sbjct: 1516 QELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLS 1575
Query: 66 --QANKDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
QA L+E+ E++ AT +VA L R +Q E +L S+E+ ++ K E +
Sbjct: 1576 GVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEK--ISKMKANETKL 1633
Query: 119 SADENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
D+ R+ +VL E+R + E + L +L+ +RL G SD ++ A ++D
Sbjct: 1634 EGDK-RRLKEVLDASESRTVKLELQRRSLEGELQRSRL------GLSDREAQAQA-LQDR 1685
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
++ + +V + K L+ ++ + +L +E SE +V
Sbjct: 1686 VDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKV 1728
Score = 49.6 bits (113), Expect = 1e-05
Identities = 41/216 (18%), Positives = 91/216 (42%), Gaps = 4/216 (1%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ + + EK N +QQA + EK+ EL+++ ++EE+
Sbjct: 594 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 653
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ ++LE +QL E + + L +++ ++ E L ++ + Q + E ++ +
Sbjct: 654 GARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKA 713
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
LE + L + L + L E +++R +A +E+E + R
Sbjct: 714 EAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQ 773
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ + + + EE + L+ L + +E A Q +E
Sbjct: 774 RQAEQEATVAREEQE----RLEELRLEQEVARQGLE 805
Score = 47.2 bits (107), Expect = 7e-05
Identities = 52/218 (23%), Positives = 94/218 (43%), Gaps = 9/218 (4%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL---AQVEEDLILNKNK 63
++Q M+ + + D T +Q D+ + E+++ L+ K Q ED +
Sbjct: 534 QVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQR 593
Query: 64 LEQANKDLEEKEKQLTATEAEVAALN-RKVQQIEEDLEKSEERSGTAQQKLLEAQQSA-D 121
L AN +L +EK A +VA +++Q E L+ ++E + +L E Q+ A
Sbjct: 594 LRSAN-ELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQ 652
Query: 122 ENNRMCKVLE---NRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
+ R+ + LE + +Q E + L +L E R A + D + + A V + L
Sbjct: 653 DGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTK 712
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
AE + +++L E + +SL L E Q
Sbjct: 713 AEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQ 750
Score = 46.4 bits (105), Expect = 1e-04
Identities = 43/196 (21%), Positives = 90/196 (45%), Gaps = 14/196 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A+ +++ M+ E+D+A +A ++ ++ V+ + +Q +LA EE + ++
Sbjct: 1534 ALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSER 1593
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQI---EEDLEKSEER------SGTAQQKL 113
+ + E+ L ATE+E+ A K+ ++ E LE + R + ++
Sbjct: 1594 ERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVK 1653
Query: 114 LEAQQSADENNRMCKVL-----ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
LE Q+ + E L E +AQ ++R+D L Q+ ++ + A + ++
Sbjct: 1654 LELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGA 1713
Query: 169 LAFVEDELEVAEDRVK 184
LA VE+ D+V+
Sbjct: 1714 LAKVEESEGALRDKVR 1729
Score = 45.2 bits (102), Expect = 3e-04
Identities = 52/230 (22%), Positives = 107/230 (46%), Gaps = 18/230 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQA-RDANLRAEKVNEEV--RELQKKLAQVEEDLIL 59
++ K++ A KL + +A EQ+A + +L+ + +E REL+ + AQ++ L
Sbjct: 963 SLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQR 1022
Query: 60 NKNKL-EQANKDLEEKEKQLTATEAEV-AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
+ +L + + EE +++ A + E L + ++ L E +KL+ +
Sbjct: 1023 EQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTR 1082
Query: 118 QSAD----ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
S E R + ++R +QD ++ LT++L++ R E+A + R+L
Sbjct: 1083 HSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQ--- 1139
Query: 174 DELEVAEDRVKSGDAKISELEE---ELKVVGNSLKSLEVSEEKANQRVEE 220
E A D K D+ + E EE +L+++ ++ L +A +++ E
Sbjct: 1140 ---EQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRE 1186
Score = 44.4 bits (100), Expect = 5e-04
Identities = 52/221 (23%), Positives = 97/221 (43%), Gaps = 21/221 (9%)
Query: 8 MQAMKLEKDNAMDKADT--CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 65
+QA K E A+ KA+ E + LRAE+ + +++ KL+ + E L +K L
Sbjct: 699 LQAEKAEVAEALTKAEAGRVELELSMTKLRAEEAS--LQDSLSKLSALNESLAQDKLDLN 756
Query: 66 QANKDLEEKEKQLTA----TEAEVAALNRKVQQIEE-DLEKSEERSGTAQQKLLEAQQSA 120
+ LEE++ L E E + +++EE LE+ R G + L A+Q+
Sbjct: 757 RLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQG-LEGSLRVAEQAQ 815
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ + L + Q +E++ QL+ QL G+ E+ + + ++E E
Sbjct: 816 EALEQQLPTLRHERSQLQEQLAQLSRQL----------SGREQELEQARREAQRQVEALE 865
Query: 181 DRVKSGDAKISE-LEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ +A E +++V + +SEE R+E+
Sbjct: 866 RAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEK 906
Score = 43.6 bits (98), Expect = 8e-04
Identities = 45/199 (22%), Positives = 88/199 (44%), Gaps = 11/199 (5%)
Query: 26 EQQARDANLRAEK----VNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT 81
E+Q RDA R E+ VN EL+ AQ EE + ++ + + + KQ +
Sbjct: 1093 ERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSC 1152
Query: 82 EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
E L +++ +E+ + AQ+KL E+Q+ + + L + +
Sbjct: 1153 LREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKER 1212
Query: 142 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 201
+ L +E R + A+ S+ +S KLA + E ++A ++ + + EL+
Sbjct: 1213 EALRRSNEELRSAVKKAE--SERISLKLANEDKEQKLA--LLEEARTAVGKEAGELR--- 1265
Query: 202 NSLKSLEVSEEKANQRVEE 220
L+ +E S +A + ++E
Sbjct: 1266 TGLQEVERSRLEARRELQE 1284
Score = 41.1 bits (92), Expect = 0.004
Identities = 40/219 (18%), Positives = 102/219 (46%), Gaps = 10/219 (4%)
Query: 5 KKKMQAMKLEKDNA---MDKADTCEQQARDA-NLRAEKVNEEVRELQKKLAQVEEDLILN 60
+++++ ++LE++ A ++ + +QA++A + + E +LQ++LAQ+ L
Sbjct: 787 QERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGR 846
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +LEQA ++ + + + L E AL ++ + L +E T ++ +
Sbjct: 847 EQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEK 906
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ ++ + Q E R +QL + + L E G+ + +++ +++ + +
Sbjct: 907 EALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDK 966
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ + K+ + E E + SL+ + E+ QR++
Sbjct: 967 ELMAQ---KLVQAEREAQA---SLREQRAAHEEDLQRLQ 999
Score = 40.7 bits (91), Expect = 0.006
Identities = 42/210 (20%), Positives = 88/210 (41%), Gaps = 13/210 (6%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+ ++++ + ++ ++ + D E++ DA +V E+ ++L Q+E +
Sbjct: 620 EELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLA 679
Query: 62 NKLEQANKDLEEKEKQ---LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
+L + + L Q L A +AEVA K + +LE S KL +
Sbjct: 680 KELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELS-------MTKLRAEEA 732
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
S ++ L QD+ +++L QL+E + + G+ + ++ +E E
Sbjct: 733 SLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQ---GRQRQAEQEATVAREEQER 789
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLE 208
E+ + LE L+V + ++LE
Sbjct: 790 LEELRLEQEVARQGLEGSLRVAEQAQEALE 819
Score = 39.5 bits (88), Expect = 0.013
Identities = 42/245 (17%), Positives = 100/245 (40%), Gaps = 4/245 (1%)
Query: 14 EKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 72
E + A+ DK + ++ ++ LQK L E D + + +L+ A + L
Sbjct: 1719 ESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALS 1778
Query: 73 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 132
E KQ ++ +V L +V +E ++E + ++ L + Q+ + L++
Sbjct: 1779 EARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQD 1838
Query: 133 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE-VAEDRVKSGDAKIS 191
+ +ER+ L L + + + + + + + L+ V ++++S + +
Sbjct: 1839 ERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTV- 1897
Query: 192 ELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQK 251
L E + +L E+ +A +++++ + + +LQ+
Sbjct: 1898 RLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQL-ELQQ 1956
Query: 252 EVDRL 256
EV+RL
Sbjct: 1957 EVERL 1961
Score = 37.9 bits (84), Expect = 0.040
Identities = 52/227 (22%), Positives = 106/227 (46%), Gaps = 19/227 (8%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+A+ K+ + ++ A + T ++A L E + + E+Q++LAQ+E +
Sbjct: 872 EALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLE----ARR 927
Query: 62 NKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIEEDL-EKSEERSGTAQQKLLEA 116
+LE + L E +L ++ A K +E + +K + AQ L E
Sbjct: 928 EQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQ 987
Query: 117 QQSADEN-NRMCKVLENRAQQDEERMDQLTNQL-KEARLLAEDADGKSDEVSRKLAFVED 174
+ + +E+ R+ + E ++ E QL +QL +E L + + +E+S ++A ++
Sbjct: 988 RAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQ 1047
Query: 175 E----LEVAE-DRVKSGDAKISE---LEEELKVVGNSLKSLEVSEEK 213
E L +AE ++ ++ K SE L E+L +SL ++ + E+
Sbjct: 1048 ERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMER 1094
Score = 37.5 bits (83), Expect = 0.053
Identities = 38/166 (22%), Positives = 82/166 (49%), Gaps = 11/166 (6%)
Query: 46 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 105
L K+ QV++ + + E + L KQL+ +E+E AL ++Q++ + + + +
Sbjct: 528 LHKRQLQVQD----MRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQA 583
Query: 106 SGTAQ---QKLLEAQQ--SADENN--RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA 158
AQ Q+L A + S +++N +V + +A++ + ++L +E R +
Sbjct: 584 HEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRL 643
Query: 159 DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL 204
+ + ++ + A V ELE + +++ + K S L +EL V +L
Sbjct: 644 EEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREAL 689
Score = 36.3 bits (80), Expect = 0.12
Identities = 34/171 (19%), Positives = 78/171 (45%), Gaps = 3/171 (1%)
Query: 11 MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE-QANK 69
+ L+++N + + + + A RAE+ +E + ++E+ L L +LE Q +
Sbjct: 77 LSLQEENQLLQQELSRVEDLLAQSRAER-DELAIKYNAVSERLEQALRLEPGELETQEPR 135
Query: 70 DLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
L + +L + E A+ RK+Q +E ++ + Q K+L+ ++ E +
Sbjct: 136 GLVRQSVELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLL 195
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+Q R + + L+ A + E+ +S +++ A + ++L+ A
Sbjct: 196 ERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQVNAMLREQLDQA 246
Score = 36.3 bits (80), Expect = 0.12
Identities = 44/217 (20%), Positives = 97/217 (44%), Gaps = 19/217 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++ + ++++ A + + + A++ + NEE+R KK E + I
Sbjct: 1184 LRESQEGREVQRQEAGELRRSLGEGAKEREA-LRRSNEELRSAVKK---AESERI----S 1235
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L+ AN+D KE++L E A+ ++ ++ L++ E + LEA++ E
Sbjct: 1236 LKLANED---KEQKLALLEEARTAVGKEAGELRTGLQEVE-------RSRLEARRELQEL 1285
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
R K+L++ + + +L +L +++ ++ + ++L E LEV +
Sbjct: 1286 RRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQEL 1345
Query: 184 KSGDAKISELEEELKV-VGNSLKSLEVSEEKANQRVE 219
+ K+ E E E + L SLE + Q+++
Sbjct: 1346 QVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLD 1382
Score = 36.3 bits (80), Expect = 0.12
Identities = 31/166 (18%), Positives = 69/166 (41%), Gaps = 4/166 (2%)
Query: 47 QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS 106
++KLA +EE + + L+E E+ E+ L R+++ ++ + +
Sbjct: 1244 EQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGREL 1303
Query: 107 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 166
Q +L +++ E+ R L R + E ++ + +L+ A+ ++ +G+
Sbjct: 1304 AELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRE 1363
Query: 167 RKLAFVEDELEVAE----DRVKSGDAKISELEEELKVVGNSLKSLE 208
R+L +E E D + + K+ E +G L + E
Sbjct: 1364 RRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAE 1409
>BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6,
cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)
protein.
Length = 1939
Score = 61.3 bits (142), Expect = 4e-09
Identities = 47/210 (22%), Positives = 111/210 (52%), Gaps = 13/210 (6%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKKM++ ++ E + A+ + E++A+ A A + EE+++ Q A +E +
Sbjct: 1729 KKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 1785
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN +EQ KDL E ++ L + ++ L +V+++E +LE ++R+ + + + +
Sbjct: 1786 KN-MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRK 1844
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
+++ E + + + ++ +D+L ++K + AE+A+ +++ K V+ E
Sbjct: 1845 SERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 1904
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLK 205
L+ AE+R ++++++L + + +G K
Sbjct: 1905 LDEAEERADIAESQVNKLRAKSRDIGAKQK 1934
Score = 56.0 bits (129), Expect = 1e-07
Identities = 54/226 (23%), Positives = 109/226 (48%), Gaps = 15/226 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 59
++ ++K+++ KLE +A+++A+ + LRA+ + N+ E+++KLA+ +E++
Sbjct: 1528 LEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 1587
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
K ++ L+ T + EV + +K +E DL + E + A + EAQ+
Sbjct: 1588 AKRNHQRVVDSLQTSLDAETRSRNEVLRVKKK---MEGDLNEMEIQLSHANRMAAEAQKQ 1644
Query: 120 ADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVSRKLA 170
+ K L++ + +++ + + N L +A L A + E SRKLA
Sbjct: 1645 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1704
Query: 171 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
E EL +RV+ ++ + L + K + + L L+ E+A Q
Sbjct: 1705 --EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQ 1748
Score = 54.0 bits (124), Expect = 6e-07
Identities = 45/214 (21%), Positives = 99/214 (46%), Gaps = 12/214 (5%)
Query: 11 MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE----Q 66
++ E+DN D + C+Q ++ ++ E +E+ E + ++ +L K KLE +
Sbjct: 893 VQAEQDNLNDAEERCDQLIKN-KIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSE 951
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
KD+++ E L E E A KV+ + E++ +E KL + +++ E ++
Sbjct: 952 LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDE----IIAKLTKEKKALQEAHQ- 1006
Query: 127 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
+ L++ Q +E++++ L+ + +D +G ++ + +E E +K
Sbjct: 1007 -QALDD-LQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLT 1064
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
I +LE + + LK E + N ++E+
Sbjct: 1065 QESIMDLENDKLQLEEKLKKKEFDINQQNSKIED 1098
Score = 52.8 bits (121), Expect = 1e-06
Identities = 42/192 (21%), Positives = 86/192 (44%), Gaps = 4/192 (2%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1424 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1483
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
L ++ E LE + + Q+++ + + E + LE +Q E +L
Sbjct: 1484 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQ 1543
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
+ L+EA E +GK + +L F + + E+ E ++ D ++ + + + V +SL+
Sbjct: 1544 SALEEAEASLEHEEGKI--LRAQLEFNQIKAEI-ERKLAEKDEEMEQAKRNHQRVVDSLQ 1600
Query: 206 -SLEVSEEKANQ 216
SL+ N+
Sbjct: 1601 TSLDAETRSRNE 1612
Score = 52.8 bits (121), Expect = 1e-06
Identities = 43/285 (15%), Positives = 120/285 (42%), Gaps = 1/285 (0%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D+++ + A ++ + E + ++ N E QK++ ++ L
Sbjct: 1596 VDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDT 1655
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L+ A + ++ ++ + E L +++++ +E++E A+Q+L+E +
Sbjct: 1656 QIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERV 1715
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L N+ ++ E + QL ++++EA +A+ K+ + A + +EL+ +
Sbjct: 1716 QLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQ 1775
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + +E+ +K + + L E ++ + +++++
Sbjct: 1776 DTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRN 1835
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K ++ + L + +K L D +D ++ Y
Sbjct: 1836 AESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAY 1880
Score = 51.2 bits (117), Expect = 4e-06
Identities = 41/178 (23%), Positives = 88/178 (49%), Gaps = 9/178 (5%)
Query: 45 ELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 104
E +K++A ++E+ K LE++ +E E+++ + E L +VQ +++L +EE
Sbjct: 846 ETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEE 905
Query: 105 RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 164
R + ++ + E N R + +EE +LT + ++ + D+
Sbjct: 906 RCDQLIKNKIQLEAKVKEMNE-------RLEDEEEMNAELTAKKRKLEDECSELKKDIDD 958
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA--NQRVEE 220
+ LA VE E E++VK+ +++ L+E + + K+L+ + ++A + +VEE
Sbjct: 959 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEE 1016
Score = 51.2 bits (117), Expect = 4e-06
Identities = 59/293 (20%), Positives = 132/293 (45%), Gaps = 20/293 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++ + ++ EK +K ++ + K+ +E + LQ+ Q +DL +
Sbjct: 956 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVE 1015
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
++K+ +K + E+Q+ E + + +++ DLE++ +R KL +
Sbjct: 1016 EDKVNSLSKSKVKLEQQVDDLEGSL----EQEKKVRMDLERA-KRKLEGDLKLTQESIMD 1070
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
EN+++ LE + ++ E ++Q +++++ ++LA K E ++ +E+ELE AE
Sbjct: 1071 LENDKL--QLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELE-AE 1127
Query: 181 DRVKSGDAKI-SELEEELKVVGNSLK----SLEVSEEKANQRVEEFXXXXXXXXXXXXXX 235
++ K+ S+L EL+ + L+ + V E +R EF
Sbjct: 1128 RTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQH 1187
Query: 236 XXXXXXXXK----TVKKLQKEVD---RLEDELGINKDRYKSLADEMDSTFAEL 281
K +V +L +++D R++ +L K +K D++ S ++
Sbjct: 1188 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQI 1240
Score = 50.4 bits (115), Expect = 7e-06
Identities = 66/290 (22%), Positives = 118/290 (40%), Gaps = 33/290 (11%)
Query: 12 KLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDL 71
KLEK+ + K + D E++ + L+K +E+ + KLE+A + L
Sbjct: 1218 KLEKEKSEFKLEL-----DDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSL 1272
Query: 72 E--------------EKEKQLTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQQKLL 114
E +QL EA ++ L R Q EDL++ E G A+ L
Sbjct: 1273 NDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALA 1332
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVS 166
A QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 1333 HALQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE 1389
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXX 226
+ L+ AE+ V++ +AK S LE+ + N ++ L V E++N
Sbjct: 1390 EAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR 1449
Query: 227 XXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
++ QKE L EL K+ Y+ + +++
Sbjct: 1450 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLET 1499
Score = 50.4 bits (115), Expect = 7e-06
Identities = 45/261 (17%), Positives = 110/261 (42%), Gaps = 8/261 (3%)
Query: 5 KKKMQAMKLEKDNAMDKADT-CEQQARDANLRAEKVNEEVRELQK---KLAQVEEDLILN 60
+ K + +++ +++A Q+ +DA E VN + L+K +L EDL+++
Sbjct: 1374 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1433
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ A L++K++ AE +K ++ + +LE S++ + + +L + + +
Sbjct: 1434 VERSNAAAAALDKKQRNFDKILAE---WKQKYEESQSELESSQKEARSLSTELFKLKNAY 1490
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+E+ + + + +E + LT QL E + + ++ + ++ LE AE
Sbjct: 1491 EESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAE 1550
Query: 181 DRVKSGDAKISELEEELKVVGNSL-KSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
++ + KI + E + + + L +E+ Q
Sbjct: 1551 ASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSR 1610
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
+ KK++ +++ +E +L
Sbjct: 1611 NEVLRVKKKMEGDLNEMEIQL 1631
Score = 48.0 bits (109), Expect = 4e-05
Identities = 53/261 (20%), Positives = 117/261 (44%), Gaps = 15/261 (5%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++KM ++ EK++ + + DA R +++ + +L+ K+ ++ E L
Sbjct: 875 LEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERL----ED 930
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE-AQQSADE 122
E+ N +L K+++L E E + L + + +E L K E+ + K+ ++ A
Sbjct: 931 EEEMNAELTAKKRKL---EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 987
Query: 123 NNRMCKVL-ENRAQQD--EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+ + K+ E +A Q+ ++ +D L + + L++ +V +E E +V
Sbjct: 988 DEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVR 1047
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + AK +LE +LK+ S+ LE + + +++++
Sbjct: 1048 MDLER---AK-RKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLA 1103
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
K +K+ Q ++ LE+EL
Sbjct: 1104 LQLQKKLKENQARIEELEEEL 1124
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/184 (15%), Positives = 88/184 (47%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K+ ++ +LQ ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 1730 KKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1789
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LE + +++R + ++++
Sbjct: 1790 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRI 1849
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + L ++D ++ + +VK+ + E EE+ + + ++ ++A
Sbjct: 1850 KELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAE 1909
Query: 216 QRVE 219
+R +
Sbjct: 1910 ERAD 1913
Score = 31.1 bits (67), Expect = 4.6
Identities = 50/271 (18%), Positives = 107/271 (39%), Gaps = 26/271 (9%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNE--EVRELQKKLAQVEEDLILNKN 62
K++ + K+ +D +++A T + +A A LR + + E+ E L +V++ L K+
Sbjct: 1168 KREAEFQKMRRD--LEEA-TLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1224
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSAD 121
+ + D+ +Q+ +A + ++R ++ Q E K EE + + +
Sbjct: 1225 EFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQT 1284
Query: 122 ENNRMCKVLENRAQ----------QDEERMDQLTNQLKEARLLAEDADGKS-DEVSRKLA 170
EN + + LE + ++M+ L QL+E +GK+ + ++ L
Sbjct: 1285 ENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEE--------EGKAKNALAHALQ 1336
Query: 171 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVS-EEKANQRVEEFXXXXXXXX 229
+ ++ ++ + +EL+ L + + E A QR EE
Sbjct: 1337 SARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1396
Query: 230 XXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
L+K RL++E+
Sbjct: 1397 QRLQDAEEAVEAVNAKCSSLEKTKHRLQNEI 1427
>BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1,
skeletal muscle, adult protein.
Length = 1939
Score = 61.3 bits (142), Expect = 4e-09
Identities = 48/202 (23%), Positives = 106/202 (52%), Gaps = 13/202 (6%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 73
E ++ + +A E++A+ A A + EE+++ Q A +E + KN LEQ KDL+
Sbjct: 1744 EMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MKKN-LEQTVKDLQH 1799
Query: 74 KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
+ + A + + +++Q++E + + E + Q++ +EA + ++ R K L +
Sbjct: 1800 RLDE--AEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQ 1857
Query: 134 AQQD-------EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
++D ++ +D+L ++K + AE+A+ +S+ K ++ ELE AE+R
Sbjct: 1858 TEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIA 1917
Query: 187 DAKISELEEELKVVGNSLKSLE 208
++++++L + + V + S E
Sbjct: 1918 ESQVNKLRVKSREVHTKIISEE 1939
Score = 58.4 bits (135), Expect = 3e-08
Identities = 50/226 (22%), Positives = 109/226 (48%), Gaps = 10/226 (4%)
Query: 4 IKKKMQA---MKLEKDNAMDKAD-TCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDL 57
IK K+Q +K + A D+ + E A+ L E ++ +++ +L+ LA+VE++
Sbjct: 913 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 972
Query: 58 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
+NK++ +++ ++ + E AL QQ +DL+ E++ T + ++ +
Sbjct: 973 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLE 1032
Query: 118 QSADENNRMCKVLENRAQQDEERMD-QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
Q D+ + E + + D ER +L LK A+ D + ++ KL E E+
Sbjct: 1033 QQVDDLEGSLE-QEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEM 1091
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSL--EVSEEKANQRVEE 220
+ +++ A +L++++K + ++ L E+ E+A++ E
Sbjct: 1092 SGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAE 1137
Score = 56.4 bits (130), Expect = 1e-07
Identities = 47/261 (18%), Positives = 115/261 (44%), Gaps = 8/261 (3%)
Query: 5 KKKMQAMKLEKDNAMDKADT-CEQQARDANLRAEKVNEEVRELQK---KLAQVEEDLILN 60
+ K + +++ +++A Q+ +DA E VN + L+K +L EDL+++
Sbjct: 1376 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMID 1435
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ A L++K++ AE +K ++ +LE S++ S + +L + + +
Sbjct: 1436 VERTNAACAALDKKQRNFDKILAE---WKQKCEETHAELEASQKESRSLSTELFKIKNAY 1492
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+E+ + L+ + ++ + LT Q+ E + +V ++ + ++ LE AE
Sbjct: 1493 EESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELKKIKKQVEQEKSELQAALEEAE 1552
Query: 181 DRVKSGDAKISELEEELKVVGNSL-KSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
++ + KI ++ EL V + + + + +E+ +Q
Sbjct: 1553 ASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSR 1612
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
+ KK++ +++ +E +L
Sbjct: 1613 NDAIRLKKKMEGDLNEMEIQL 1633
Score = 53.2 bits (122), Expect = 1e-06
Identities = 57/286 (19%), Positives = 124/286 (43%), Gaps = 10/286 (3%)
Query: 1 MDA-IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
+DA I+ + A++L+K D + E Q AN A + R Q L +D L
Sbjct: 1605 LDAEIRSRNDAIRLKKKMEGD-LNEMEIQLNHANRMAAEALRNYRNTQAIL----KDTQL 1659
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
+ L+ A + E+ ++QL E L +++++ LE++E A+Q+LL+A +
Sbjct: 1660 H---LDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASER 1716
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+ L N ++ E + Q+ ++++ A +A+ K+ + A + +EL+
Sbjct: 1717 VQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKE 1776
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXX 238
+D + LE+ +K + + L E ++ + +++++
Sbjct: 1777 QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKR 1836
Query: 239 XXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K +++V L + ++ L D +D A++ Y
Sbjct: 1837 NVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSY 1882
Score = 49.6 bits (113), Expect = 1e-05
Identities = 51/261 (19%), Positives = 115/261 (44%), Gaps = 15/261 (5%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++KM + EK++ + DA R +++ + +L+ K+ +V E
Sbjct: 877 LEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTE----RAED 932
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE-AQQSADE 122
E+ N +L K+++L E E + L + + +E L K E+ + K+ ++ A
Sbjct: 933 EEEINAELTAKKRKL---EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 989
Query: 123 NNRMCKVL-ENRAQQD--EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+ + K+ E +A Q+ ++ +D L + + L + +V +E E ++
Sbjct: 990 DETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIR 1049
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + AK +LE +LK+ S +E +++ ++++++
Sbjct: 1050 MDLER---AK-RKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALG 1105
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
K +K+LQ ++ LE+E+
Sbjct: 1106 MQLQKKIKELQARIEELEEEI 1126
Score = 48.0 bits (109), Expect = 4e-05
Identities = 40/205 (19%), Positives = 94/205 (45%), Gaps = 7/205 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++ + ++ EK +K ++ + K+ +E + LQ+ Q +DL
Sbjct: 958 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAE 1017
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
++K+ K + E+Q+ E + + ++I DLE++ +R KL +
Sbjct: 1018 EDKVNTLTKAKIKLEQQVDDLEGSL----EQEKKIRMDLERA-KRKLEGDLKLAQESTMD 1072
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
EN++ + L+ + ++ E M L +++++ + L K E+ ++ +E+E+E
Sbjct: 1073 IENDK--QQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAER 1130
Query: 181 DRVKSGDAKISELEEELKVVGNSLK 205
+ + S+L EL+ + L+
Sbjct: 1131 ASRAKAEKQRSDLSRELEEISERLE 1155
Score = 47.6 bits (108), Expect = 5e-05
Identities = 30/165 (18%), Positives = 80/165 (48%)
Query: 49 KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 108
K A+ E+++ K + E+ ++L + E + E ++ L ++ ++ ++ +
Sbjct: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLAD 904
Query: 109 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
A+++ + ++ + K + RA+ +EE +LT + ++ + D++
Sbjct: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
Query: 169 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
LA VE E E++VK+ +++ L+E + + K+L+ + ++
Sbjct: 965 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQ 1009
Score = 47.6 bits (108), Expect = 5e-05
Identities = 36/186 (19%), Positives = 84/186 (45%), Gaps = 3/186 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
QQ D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1008 QQTLD-DLQAEE--DKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLK 1064
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
IE D ++ +E+ + ++ Q ++ + L+ + ++ + R+++L
Sbjct: 1065 LAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEE 1124
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
+++ R A+ + ++SR+L + + LE A + + E E + + L+
Sbjct: 1125 EIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE 1184
Query: 207 LEVSEE 212
+ E
Sbjct: 1185 ATLQHE 1190
Score = 46.8 bits (106), Expect = 9e-05
Identities = 49/230 (21%), Positives = 108/230 (46%), Gaps = 15/230 (6%)
Query: 1 MDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
++ K+K++ +KL +++ MD + ++Q D L+ ++ E+ LQ K+ + +
Sbjct: 1052 LERAKRKLEGDLKLAQESTMDIEN--DKQQLDEKLKKKEF--EMSGLQSKIEDEQALGMQ 1107
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER---SGTAQQKLLEA 116
+ K+++ +EE E+++ A A A ++ + +LE+ ER +G A +E
Sbjct: 1108 LQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEM 1167
Query: 117 QQSAD-ENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVED 174
+ + E +M + LE Q E L + ++ L E D V +KL +
Sbjct: 1168 NKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQID-NLQRVKQKLEKEKS 1226
Query: 175 ELEVAEDRVKSGDAKISE----LEEELKVVGNSLKSLEVSEEKANQRVEE 220
E+++ D + S +S+ LE+ + + + L ++ EE+ + + +
Sbjct: 1227 EMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLIND 1276
Score = 46.0 bits (104), Expect = 2e-04
Identities = 30/184 (16%), Positives = 88/184 (47%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K+ ++ ++Q ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 1732 KKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLE 1791
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LE + +++R + L++
Sbjct: 1792 QTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKV 1851
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + + ++D ++ + +VKS + E EE+ V + + ++ E+A
Sbjct: 1852 KELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAE 1911
Query: 216 QRVE 219
+R +
Sbjct: 1912 ERAD 1915
Score = 43.2 bits (97), Expect = 0.001
Identities = 54/274 (19%), Positives = 118/274 (43%), Gaps = 22/274 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++K +A++ + K + ++ D + ++ E E ++L + ++ L+ ++
Sbjct: 1249 LEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDE-KDTLVSQLSR 1307
Query: 64 LEQA-NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+QA + +EE ++QL +AL +Q D + E+ Q+ E Q++ +
Sbjct: 1308 GKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSK 1367
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
N +V + R + + + + Q T +L+EA+ +KLA L+ AE+
Sbjct: 1368 AN--SEVAQWRTKYETDAI-QRTEELEEAK--------------KKLA---QRLQDAEEH 1407
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXX 242
V++ +AK + LE+ + + N ++ L + E+ N
Sbjct: 1408 VEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEET 1467
Query: 243 XKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
++ QKE L EL K+ Y+ D++++
Sbjct: 1468 HAELEASQKESRSLSTELFKIKNAYEESLDQLET 1501
Score = 41.9 bits (94), Expect = 0.002
Identities = 53/221 (23%), Positives = 101/221 (45%), Gaps = 31/221 (14%)
Query: 24 TCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDLIL---NKNKLE---QAN----KDL 71
+ E + AN++ E K EE+ + + K ++EE ++ KN L+ QA D
Sbjct: 846 SAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADA 905
Query: 72 EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE 131
EE+ QL T+ ++ A K++++ E E EE + K + + E + LE
Sbjct: 906 EERCDQLIKTKIQLEA---KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 962
Query: 132 NRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR----KLAFVE------DELEVAED 181
+ E+ N++K L E+ G + +++ K A E D+L+ ED
Sbjct: 963 LTLAKVEKEKHATENKVKN---LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEED 1019
Query: 182 RVKSGDAKISELEEELKVVGNSL---KSLEVSEEKANQRVE 219
+V + +LE+++ + SL K + + E+A +++E
Sbjct: 1020 KVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLE 1060
Score = 39.1 bits (87), Expect = 0.017
Identities = 30/161 (18%), Positives = 81/161 (50%), Gaps = 9/161 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ +KK ++ + + +D+A+ + + + +K+ VREL+ +VE + N
Sbjct: 1783 LERMKKNLEQTVKDLQHRLDEAE--QLALKGGKKQIQKLEARVRELE---GEVESEQKRN 1837
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
++ K E K K+LT E + + ++++ ++K + + + +++ EA++ +
Sbjct: 1838 VEAVKGLRKH-ERKVKELTYQTEED---RKNILRLQDLVDKLQAKVKSYKRQAEEAEEQS 1893
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
+ N + +++ ++ EER D +Q+ + R+ + + K
Sbjct: 1894 NVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVHTK 1934
>AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet coiled-coil,
rootletin protein.
Length = 1898
Score = 61.3 bits (142), Expect = 4e-09
Identities = 44/190 (23%), Positives = 91/190 (47%), Gaps = 2/190 (1%)
Query: 20 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 79
D+ D+ ++Q D+ ++A + V L LA+VEE ++K+ + L + L
Sbjct: 1565 DRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLN 1624
Query: 80 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 139
+T + L + + E D + +ER A+Q L EA++ + + L E
Sbjct: 1625 STRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLEL 1684
Query: 140 RMDQLTNQLKEAR-LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 198
+ + QL++ R +L + +G++ ++ + ++DE + ++R+ S +++LE E +
Sbjct: 1685 QRVEAEGQLQQLREVLRQRQEGEAAALN-TVQKLQDERRLLQERLGSLQRALAQLEAEKR 1743
Query: 199 VVGNSLKSLE 208
V S LE
Sbjct: 1744 EVERSALRLE 1753
Score = 55.6 bits (128), Expect = 2e-07
Identities = 58/263 (22%), Positives = 121/263 (46%), Gaps = 23/263 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++K + A + ++ ++ D Q +A ++ + E+V+ L+ ++A +E + + +
Sbjct: 1633 LQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQ 1692
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L+Q + L +++ E E AALN VQ+++++ +ER G+ Q+ L + + E
Sbjct: 1693 LQQLREVLRQRQ------EGEAAALN-TVQKLQDERRLLQERLGSLQRALAQLEAEKREV 1745
Query: 124 NRMCKVLEN-----RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
R LE R D+ ++L + RL AE G+ D R L E EL
Sbjct: 1746 ERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAE--KGRLD---RTLTGAELELAE 1800
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEV-SEEKANQRVEEFXXXXXXXXXXXXXXXX 237
A+ +++ +A++ LE+ +S LEV ++++ + +E
Sbjct: 1801 AQRQIQQLEAQVVVLEQ-----SHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEA 1855
Query: 238 XXXXXXKTVKKLQKEVDRLEDEL 260
+ V+ L+++V L+ +L
Sbjct: 1856 RERAHRQRVRGLEEQVSTLKGQL 1878
Score = 53.6 bits (123), Expect = 8e-07
Identities = 53/223 (23%), Positives = 105/223 (47%), Gaps = 20/223 (8%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 65
+++++ + E+D + +Q + + R+LQK +A+ EE +L
Sbjct: 1397 QELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLS 1456
Query: 66 --QANKDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
QA L+E+ E++ AT +VA L R +Q E +L S+E+ ++ K E +
Sbjct: 1457 GVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEK--ISKMKANETKL 1514
Query: 119 SADENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
D+ R+ +VL E+R + E + L +L+ +RL G SD ++ A ++D
Sbjct: 1515 EGDK-RRLKEVLDASESRTVKLELQRRSLEGELQRSRL------GLSDREAQAQA-LQDR 1566
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
++ + +V + K L+ ++ + +L +E SE +V
Sbjct: 1567 VDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKV 1609
Score = 49.6 bits (113), Expect = 1e-05
Identities = 41/216 (18%), Positives = 91/216 (42%), Gaps = 4/216 (1%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ + + EK N +QQA + EK+ EL+++ ++EE+
Sbjct: 475 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 534
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ ++LE +QL E + + L +++ ++ E L ++ + Q + E ++ +
Sbjct: 535 GARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKA 594
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
LE + L + L + L E +++R +A +E+E + R
Sbjct: 595 EAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQ 654
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ + + + EE + L+ L + +E A Q +E
Sbjct: 655 RQAEQEATVAREEQE----RLEELRLEQEVARQGLE 686
Score = 47.2 bits (107), Expect = 7e-05
Identities = 52/218 (23%), Positives = 94/218 (43%), Gaps = 9/218 (4%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL---AQVEEDLILNKNK 63
++Q M+ + + D T +Q D+ + E+++ L+ K Q ED +
Sbjct: 415 QVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQR 474
Query: 64 LEQANKDLEEKEKQLTATEAEVAALN-RKVQQIEEDLEKSEERSGTAQQKLLEAQQSA-D 121
L AN +L +EK A +VA +++Q E L+ ++E + +L E Q+ A
Sbjct: 475 LRSAN-ELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQ 533
Query: 122 ENNRMCKVLE---NRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
+ R+ + LE + +Q E + L +L E R A + D + + A V + L
Sbjct: 534 DGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTK 593
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
AE + +++L E + +SL L E Q
Sbjct: 594 AEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQ 631
Score = 46.4 bits (105), Expect = 1e-04
Identities = 43/196 (21%), Positives = 90/196 (45%), Gaps = 14/196 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A+ +++ M+ E+D+A +A ++ ++ V+ + +Q +LA EE + ++
Sbjct: 1415 ALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSER 1474
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQI---EEDLEKSEER------SGTAQQKL 113
+ + E+ L ATE+E+ A K+ ++ E LE + R + ++
Sbjct: 1475 ERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVK 1534
Query: 114 LEAQQSADENNRMCKVL-----ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
LE Q+ + E L E +AQ ++R+D L Q+ ++ + A + ++
Sbjct: 1535 LELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGA 1594
Query: 169 LAFVEDELEVAEDRVK 184
LA VE+ D+V+
Sbjct: 1595 LAKVEESEGALRDKVR 1610
Score = 45.2 bits (102), Expect = 3e-04
Identities = 52/230 (22%), Positives = 107/230 (46%), Gaps = 18/230 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQA-RDANLRAEKVNEEV--RELQKKLAQVEEDLIL 59
++ K++ A KL + +A EQ+A + +L+ + +E REL+ + AQ++ L
Sbjct: 844 SLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQR 903
Query: 60 NKNKL-EQANKDLEEKEKQLTATEAEV-AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
+ +L + + EE +++ A + E L + ++ L E +KL+ +
Sbjct: 904 EQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTR 963
Query: 118 QSAD----ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
S E R + ++R +QD ++ LT++L++ R E+A + R+L
Sbjct: 964 HSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQ--- 1020
Query: 174 DELEVAEDRVKSGDAKISELEE---ELKVVGNSLKSLEVSEEKANQRVEE 220
E A D K D+ + E EE +L+++ ++ L +A +++ E
Sbjct: 1021 ---EQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRE 1067
Score = 44.4 bits (100), Expect = 5e-04
Identities = 52/221 (23%), Positives = 97/221 (43%), Gaps = 21/221 (9%)
Query: 8 MQAMKLEKDNAMDKADT--CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 65
+QA K E A+ KA+ E + LRAE+ + +++ KL+ + E L +K L
Sbjct: 580 LQAEKAEVAEALTKAEAGRVELELSMTKLRAEEAS--LQDSLSKLSALNESLAQDKLDLN 637
Query: 66 QANKDLEEKEKQLTA----TEAEVAALNRKVQQIEE-DLEKSEERSGTAQQKLLEAQQSA 120
+ LEE++ L E E + +++EE LE+ R G + L A+Q+
Sbjct: 638 RLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQG-LEGSLRVAEQAQ 696
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ + L + Q +E++ QL+ QL G+ E+ + + ++E E
Sbjct: 697 EALEQQLPTLRHERSQLQEQLAQLSRQL----------SGREQELEQARREAQRQVEALE 746
Query: 181 DRVKSGDAKISE-LEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ +A E +++V + +SEE R+E+
Sbjct: 747 RAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEK 787
Score = 43.6 bits (98), Expect = 8e-04
Identities = 45/199 (22%), Positives = 88/199 (44%), Gaps = 11/199 (5%)
Query: 26 EQQARDANLRAEK----VNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT 81
E+Q RDA R E+ VN EL+ AQ EE + ++ + + + KQ +
Sbjct: 974 ERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSC 1033
Query: 82 EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
E L +++ +E+ + AQ+KL E+Q+ + + L + +
Sbjct: 1034 LREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKER 1093
Query: 142 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 201
+ L +E R + A+ S+ +S KLA + E ++A ++ + + EL+
Sbjct: 1094 EALRRSNEELRSAVKKAE--SERISLKLANEDKEQKLA--LLEEARTAVGKEAGELR--- 1146
Query: 202 NSLKSLEVSEEKANQRVEE 220
L+ +E S +A + ++E
Sbjct: 1147 TGLQEVERSRLEARRELQE 1165
Score = 41.1 bits (92), Expect = 0.004
Identities = 40/219 (18%), Positives = 102/219 (46%), Gaps = 10/219 (4%)
Query: 5 KKKMQAMKLEKDNA---MDKADTCEQQARDA-NLRAEKVNEEVRELQKKLAQVEEDLILN 60
+++++ ++LE++ A ++ + +QA++A + + E +LQ++LAQ+ L
Sbjct: 668 QERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGR 727
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +LEQA ++ + + + L E AL ++ + L +E T ++ +
Sbjct: 728 EQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEK 787
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ ++ + Q E R +QL + + L E G+ + +++ +++ + +
Sbjct: 788 EALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDK 847
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ + K+ + E E + SL+ + E+ QR++
Sbjct: 848 ELMAQ---KLVQAEREAQA---SLREQRAAHEEDLQRLQ 880
Score = 40.7 bits (91), Expect = 0.006
Identities = 42/210 (20%), Positives = 88/210 (41%), Gaps = 13/210 (6%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+ ++++ + ++ ++ + D E++ DA +V E+ ++L Q+E +
Sbjct: 501 EELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLA 560
Query: 62 NKLEQANKDLEEKEKQ---LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
+L + + L Q L A +AEVA K + +LE S KL +
Sbjct: 561 KELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELS-------MTKLRAEEA 613
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
S ++ L QD+ +++L QL+E + + G+ + ++ +E E
Sbjct: 614 SLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQ---GRQRQAEQEATVAREEQER 670
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLE 208
E+ + LE L+V + ++LE
Sbjct: 671 LEELRLEQEVARQGLEGSLRVAEQAQEALE 700
Score = 39.5 bits (88), Expect = 0.013
Identities = 42/245 (17%), Positives = 100/245 (40%), Gaps = 4/245 (1%)
Query: 14 EKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 72
E + A+ DK + ++ ++ LQK L E D + + +L+ A + L
Sbjct: 1600 ESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALS 1659
Query: 73 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 132
E KQ ++ +V L +V +E ++E + ++ L + Q+ + L++
Sbjct: 1660 EARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQD 1719
Query: 133 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE-VAEDRVKSGDAKIS 191
+ +ER+ L L + + + + + + + L+ V ++++S + +
Sbjct: 1720 ERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTV- 1778
Query: 192 ELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQK 251
L E + +L E+ +A +++++ + + +LQ+
Sbjct: 1779 RLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQL-ELQQ 1837
Query: 252 EVDRL 256
EV+RL
Sbjct: 1838 EVERL 1842
Score = 37.9 bits (84), Expect = 0.040
Identities = 52/227 (22%), Positives = 106/227 (46%), Gaps = 19/227 (8%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+A+ K+ + ++ A + T ++A L E + + E+Q++LAQ+E +
Sbjct: 753 EALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLE----ARR 808
Query: 62 NKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIEEDL-EKSEERSGTAQQKLLEA 116
+LE + L E +L ++ A K +E + +K + AQ L E
Sbjct: 809 EQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQ 868
Query: 117 QQSADEN-NRMCKVLENRAQQDEERMDQLTNQL-KEARLLAEDADGKSDEVSRKLAFVED 174
+ + +E+ R+ + E ++ E QL +QL +E L + + +E+S ++A ++
Sbjct: 869 RAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQ 928
Query: 175 E----LEVAE-DRVKSGDAKISE---LEEELKVVGNSLKSLEVSEEK 213
E L +AE ++ ++ K SE L E+L +SL ++ + E+
Sbjct: 929 ERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMER 975
Score = 37.5 bits (83), Expect = 0.053
Identities = 38/166 (22%), Positives = 82/166 (49%), Gaps = 11/166 (6%)
Query: 46 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 105
L K+ QV++ + + E + L KQL+ +E+E AL ++Q++ + + + +
Sbjct: 409 LHKRQLQVQD----MRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQA 464
Query: 106 SGTAQ---QKLLEAQQ--SADENN--RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA 158
AQ Q+L A + S +++N +V + +A++ + ++L +E R +
Sbjct: 465 HEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRL 524
Query: 159 DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL 204
+ + ++ + A V ELE + +++ + K S L +EL V +L
Sbjct: 525 EEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREAL 570
Score = 36.3 bits (80), Expect = 0.12
Identities = 44/217 (20%), Positives = 97/217 (44%), Gaps = 19/217 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++ + ++++ A + + + A++ + NEE+R KK E + I
Sbjct: 1065 LRESQEGREVQRQEAGELRRSLGEGAKEREA-LRRSNEELRSAVKK---AESERI----S 1116
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L+ AN+D KE++L E A+ ++ ++ L++ E + LEA++ E
Sbjct: 1117 LKLANED---KEQKLALLEEARTAVGKEAGELRTGLQEVE-------RSRLEARRELQEL 1166
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
R K+L++ + + +L +L +++ ++ + ++L E LEV +
Sbjct: 1167 RRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQEL 1226
Query: 184 KSGDAKISELEEELKV-VGNSLKSLEVSEEKANQRVE 219
+ K+ E E E + L SLE + Q+++
Sbjct: 1227 QVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLD 1263
Score = 36.3 bits (80), Expect = 0.12
Identities = 31/166 (18%), Positives = 69/166 (41%), Gaps = 4/166 (2%)
Query: 47 QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS 106
++KLA +EE + + L+E E+ E+ L R+++ ++ + +
Sbjct: 1125 EQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGREL 1184
Query: 107 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 166
Q +L +++ E+ R L R + E ++ + +L+ A+ ++ +G+
Sbjct: 1185 AELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRE 1244
Query: 167 RKLAFVEDELEVAE----DRVKSGDAKISELEEELKVVGNSLKSLE 208
R+L +E E D + + K+ E +G L + E
Sbjct: 1245 RRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAE 1290
>AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet coiled-coil,
rootletin protein.
Length = 2017
Score = 61.3 bits (142), Expect = 4e-09
Identities = 44/190 (23%), Positives = 91/190 (47%), Gaps = 2/190 (1%)
Query: 20 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 79
D+ D+ ++Q D+ ++A + V L LA+VEE ++K+ + L + L
Sbjct: 1684 DRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLN 1743
Query: 80 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 139
+T + L + + E D + +ER A+Q L EA++ + + L E
Sbjct: 1744 STRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLEL 1803
Query: 140 RMDQLTNQLKEAR-LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 198
+ + QL++ R +L + +G++ ++ + ++DE + ++R+ S +++LE E +
Sbjct: 1804 QRVEAEGQLQQLREVLRQRQEGEAAALN-TVQKLQDERRLLQERLGSLQRALAQLEAEKR 1862
Query: 199 VVGNSLKSLE 208
V S LE
Sbjct: 1863 EVERSALRLE 1872
Score = 55.6 bits (128), Expect = 2e-07
Identities = 58/263 (22%), Positives = 121/263 (46%), Gaps = 23/263 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++K + A + ++ ++ D Q +A ++ + E+V+ L+ ++A +E + + +
Sbjct: 1752 LQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQ 1811
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L+Q + L +++ E E AALN VQ+++++ +ER G+ Q+ L + + E
Sbjct: 1812 LQQLREVLRQRQ------EGEAAALN-TVQKLQDERRLLQERLGSLQRALAQLEAEKREV 1864
Query: 124 NRMCKVLEN-----RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
R LE R D+ ++L + RL AE G+ D R L E EL
Sbjct: 1865 ERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAE--KGRLD---RTLTGAELELAE 1919
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEV-SEEKANQRVEEFXXXXXXXXXXXXXXXX 237
A+ +++ +A++ LE+ +S LEV ++++ + +E
Sbjct: 1920 AQRQIQQLEAQVVVLEQ-----SHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEA 1974
Query: 238 XXXXXXKTVKKLQKEVDRLEDEL 260
+ V+ L+++V L+ +L
Sbjct: 1975 RERAHRQRVRGLEEQVSTLKGQL 1997
Score = 53.6 bits (123), Expect = 8e-07
Identities = 53/223 (23%), Positives = 105/223 (47%), Gaps = 20/223 (8%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 65
+++++ + E+D + +Q + + R+LQK +A+ EE +L
Sbjct: 1516 QELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLS 1575
Query: 66 --QANKDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
QA L+E+ E++ AT +VA L R +Q E +L S+E+ ++ K E +
Sbjct: 1576 GVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEK--ISKMKANETKL 1633
Query: 119 SADENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
D+ R+ +VL E+R + E + L +L+ +RL G SD ++ A ++D
Sbjct: 1634 EGDK-RRLKEVLDASESRTVKLELQRRSLEGELQRSRL------GLSDREAQAQA-LQDR 1685
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
++ + +V + K L+ ++ + +L +E SE +V
Sbjct: 1686 VDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKV 1728
Score = 49.6 bits (113), Expect = 1e-05
Identities = 41/216 (18%), Positives = 91/216 (42%), Gaps = 4/216 (1%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ + + EK N +QQA + EK+ EL+++ ++EE+
Sbjct: 594 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 653
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ ++LE +QL E + + L +++ ++ E L ++ + Q + E ++ +
Sbjct: 654 GARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKA 713
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
LE + L + L + L E +++R +A +E+E + R
Sbjct: 714 EAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQ 773
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ + + + EE + L+ L + +E A Q +E
Sbjct: 774 RQAEQEATVAREEQE----RLEELRLEQEVARQGLE 805
Score = 47.2 bits (107), Expect = 7e-05
Identities = 52/218 (23%), Positives = 94/218 (43%), Gaps = 9/218 (4%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL---AQVEEDLILNKNK 63
++Q M+ + + D T +Q D+ + E+++ L+ K Q ED +
Sbjct: 534 QVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQR 593
Query: 64 LEQANKDLEEKEKQLTATEAEVAALN-RKVQQIEEDLEKSEERSGTAQQKLLEAQQSA-D 121
L AN +L +EK A +VA +++Q E L+ ++E + +L E Q+ A
Sbjct: 594 LRSAN-ELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQ 652
Query: 122 ENNRMCKVLE---NRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
+ R+ + LE + +Q E + L +L E R A + D + + A V + L
Sbjct: 653 DGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTK 712
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
AE + +++L E + +SL L E Q
Sbjct: 713 AEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQ 750
Score = 46.4 bits (105), Expect = 1e-04
Identities = 43/196 (21%), Positives = 90/196 (45%), Gaps = 14/196 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A+ +++ M+ E+D+A +A ++ ++ V+ + +Q +LA EE + ++
Sbjct: 1534 ALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSER 1593
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQI---EEDLEKSEER------SGTAQQKL 113
+ + E+ L ATE+E+ A K+ ++ E LE + R + ++
Sbjct: 1594 ERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVK 1653
Query: 114 LEAQQSADENNRMCKVL-----ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
LE Q+ + E L E +AQ ++R+D L Q+ ++ + A + ++
Sbjct: 1654 LELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGA 1713
Query: 169 LAFVEDELEVAEDRVK 184
LA VE+ D+V+
Sbjct: 1714 LAKVEESEGALRDKVR 1729
Score = 45.2 bits (102), Expect = 3e-04
Identities = 52/230 (22%), Positives = 107/230 (46%), Gaps = 18/230 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQA-RDANLRAEKVNEEV--RELQKKLAQVEEDLIL 59
++ K++ A KL + +A EQ+A + +L+ + +E REL+ + AQ++ L
Sbjct: 963 SLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQR 1022
Query: 60 NKNKL-EQANKDLEEKEKQLTATEAEV-AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
+ +L + + EE +++ A + E L + ++ L E +KL+ +
Sbjct: 1023 EQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTR 1082
Query: 118 QSAD----ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
S E R + ++R +QD ++ LT++L++ R E+A + R+L
Sbjct: 1083 HSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQ--- 1139
Query: 174 DELEVAEDRVKSGDAKISELEE---ELKVVGNSLKSLEVSEEKANQRVEE 220
E A D K D+ + E EE +L+++ ++ L +A +++ E
Sbjct: 1140 ---EQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRE 1186
Score = 44.4 bits (100), Expect = 5e-04
Identities = 52/221 (23%), Positives = 97/221 (43%), Gaps = 21/221 (9%)
Query: 8 MQAMKLEKDNAMDKADT--CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 65
+QA K E A+ KA+ E + LRAE+ + +++ KL+ + E L +K L
Sbjct: 699 LQAEKAEVAEALTKAEAGRVELELSMTKLRAEEAS--LQDSLSKLSALNESLAQDKLDLN 756
Query: 66 QANKDLEEKEKQLTA----TEAEVAALNRKVQQIEE-DLEKSEERSGTAQQKLLEAQQSA 120
+ LEE++ L E E + +++EE LE+ R G + L A+Q+
Sbjct: 757 RLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQG-LEGSLRVAEQAQ 815
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ + L + Q +E++ QL+ QL G+ E+ + + ++E E
Sbjct: 816 EALEQQLPTLRHERSQLQEQLAQLSRQL----------SGREQELEQARREAQRQVEALE 865
Query: 181 DRVKSGDAKISE-LEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ +A E +++V + +SEE R+E+
Sbjct: 866 RAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEK 906
Score = 43.6 bits (98), Expect = 8e-04
Identities = 45/199 (22%), Positives = 88/199 (44%), Gaps = 11/199 (5%)
Query: 26 EQQARDANLRAEK----VNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT 81
E+Q RDA R E+ VN EL+ AQ EE + ++ + + + KQ +
Sbjct: 1093 ERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSC 1152
Query: 82 EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
E L +++ +E+ + AQ+KL E+Q+ + + L + +
Sbjct: 1153 LREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKER 1212
Query: 142 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 201
+ L +E R + A+ S+ +S KLA + E ++A ++ + + EL+
Sbjct: 1213 EALRRSNEELRSAVKKAE--SERISLKLANEDKEQKLA--LLEEARTAVGKEAGELR--- 1265
Query: 202 NSLKSLEVSEEKANQRVEE 220
L+ +E S +A + ++E
Sbjct: 1266 TGLQEVERSRLEARRELQE 1284
Score = 41.1 bits (92), Expect = 0.004
Identities = 40/219 (18%), Positives = 102/219 (46%), Gaps = 10/219 (4%)
Query: 5 KKKMQAMKLEKDNA---MDKADTCEQQARDA-NLRAEKVNEEVRELQKKLAQVEEDLILN 60
+++++ ++LE++ A ++ + +QA++A + + E +LQ++LAQ+ L
Sbjct: 787 QERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGR 846
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +LEQA ++ + + + L E AL ++ + L +E T ++ +
Sbjct: 847 EQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEK 906
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ ++ + Q E R +QL + + L E G+ + +++ +++ + +
Sbjct: 907 EALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDK 966
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ + K+ + E E + SL+ + E+ QR++
Sbjct: 967 ELMAQ---KLVQAEREAQA---SLREQRAAHEEDLQRLQ 999
Score = 40.7 bits (91), Expect = 0.006
Identities = 42/210 (20%), Positives = 88/210 (41%), Gaps = 13/210 (6%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+ ++++ + ++ ++ + D E++ DA +V E+ ++L Q+E +
Sbjct: 620 EELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLA 679
Query: 62 NKLEQANKDLEEKEKQ---LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
+L + + L Q L A +AEVA K + +LE S KL +
Sbjct: 680 KELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELS-------MTKLRAEEA 732
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
S ++ L QD+ +++L QL+E + + G+ + ++ +E E
Sbjct: 733 SLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQ---GRQRQAEQEATVAREEQER 789
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLE 208
E+ + LE L+V + ++LE
Sbjct: 790 LEELRLEQEVARQGLEGSLRVAEQAQEALE 819
Score = 39.5 bits (88), Expect = 0.013
Identities = 42/245 (17%), Positives = 100/245 (40%), Gaps = 4/245 (1%)
Query: 14 EKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 72
E + A+ DK + ++ ++ LQK L E D + + +L+ A + L
Sbjct: 1719 ESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALS 1778
Query: 73 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 132
E KQ ++ +V L +V +E ++E + ++ L + Q+ + L++
Sbjct: 1779 EARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQD 1838
Query: 133 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE-VAEDRVKSGDAKIS 191
+ +ER+ L L + + + + + + + L+ V ++++S + +
Sbjct: 1839 ERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTV- 1897
Query: 192 ELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQK 251
L E + +L E+ +A +++++ + + +LQ+
Sbjct: 1898 RLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQL-ELQQ 1956
Query: 252 EVDRL 256
EV+RL
Sbjct: 1957 EVERL 1961
Score = 37.9 bits (84), Expect = 0.040
Identities = 52/227 (22%), Positives = 106/227 (46%), Gaps = 19/227 (8%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+A+ K+ + ++ A + T ++A L E + + E+Q++LAQ+E +
Sbjct: 872 EALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLE----ARR 927
Query: 62 NKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIEEDL-EKSEERSGTAQQKLLEA 116
+LE + L E +L ++ A K +E + +K + AQ L E
Sbjct: 928 EQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQ 987
Query: 117 QQSADEN-NRMCKVLENRAQQDEERMDQLTNQL-KEARLLAEDADGKSDEVSRKLAFVED 174
+ + +E+ R+ + E ++ E QL +QL +E L + + +E+S ++A ++
Sbjct: 988 RAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQ 1047
Query: 175 E----LEVAE-DRVKSGDAKISE---LEEELKVVGNSLKSLEVSEEK 213
E L +AE ++ ++ K SE L E+L +SL ++ + E+
Sbjct: 1048 ERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMER 1094
Score = 37.5 bits (83), Expect = 0.053
Identities = 38/166 (22%), Positives = 82/166 (49%), Gaps = 11/166 (6%)
Query: 46 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 105
L K+ QV++ + + E + L KQL+ +E+E AL ++Q++ + + + +
Sbjct: 528 LHKRQLQVQD----MRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQA 583
Query: 106 SGTAQ---QKLLEAQQ--SADENN--RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA 158
AQ Q+L A + S +++N +V + +A++ + ++L +E R +
Sbjct: 584 HEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRL 643
Query: 159 DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL 204
+ + ++ + A V ELE + +++ + K S L +EL V +L
Sbjct: 644 EEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREAL 689
Score = 36.3 bits (80), Expect = 0.12
Identities = 34/171 (19%), Positives = 78/171 (45%), Gaps = 3/171 (1%)
Query: 11 MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE-QANK 69
+ L+++N + + + + A RAE+ +E + ++E+ L L +LE Q +
Sbjct: 77 LSLQEENQLLQQELSRVEDLLAQSRAER-DELAIKYNAVSERLEQALRLEPGELETQEPR 135
Query: 70 DLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
L + +L + E A+ RK+Q +E ++ + Q K+L+ ++ E +
Sbjct: 136 GLVRQSVELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLL 195
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+Q R + + L+ A + E+ +S +++ A + ++L+ A
Sbjct: 196 ERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQVNAMLREQLDQA 246
Score = 36.3 bits (80), Expect = 0.12
Identities = 44/217 (20%), Positives = 97/217 (44%), Gaps = 19/217 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++ + ++++ A + + + A++ + NEE+R KK E + I
Sbjct: 1184 LRESQEGREVQRQEAGELRRSLGEGAKEREA-LRRSNEELRSAVKK---AESERI----S 1235
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L+ AN+D KE++L E A+ ++ ++ L++ E + LEA++ E
Sbjct: 1236 LKLANED---KEQKLALLEEARTAVGKEAGELRTGLQEVE-------RSRLEARRELQEL 1285
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
R K+L++ + + +L +L +++ ++ + ++L E LEV +
Sbjct: 1286 RRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQEL 1345
Query: 184 KSGDAKISELEEELKV-VGNSLKSLEVSEEKANQRVE 219
+ K+ E E E + L SLE + Q+++
Sbjct: 1346 QVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLD 1382
Score = 36.3 bits (80), Expect = 0.12
Identities = 31/166 (18%), Positives = 69/166 (41%), Gaps = 4/166 (2%)
Query: 47 QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS 106
++KLA +EE + + L+E E+ E+ L R+++ ++ + +
Sbjct: 1244 EQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGREL 1303
Query: 107 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 166
Q +L +++ E+ R L R + E ++ + +L+ A+ ++ +G+
Sbjct: 1304 AELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRE 1363
Query: 167 RKLAFVEDELEVAE----DRVKSGDAKISELEEELKVVGNSLKSLE 208
R+L +E E D + + K+ E +G L + E
Sbjct: 1364 RRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAE 1409
>AF527734-1|AAP85633.1| 439|Homo sapiens medulloblastoma antigen
MU-MB-2.42 protein.
Length = 439
Score = 61.3 bits (142), Expect = 4e-09
Identities = 44/190 (23%), Positives = 91/190 (47%), Gaps = 2/190 (1%)
Query: 20 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 79
D+ D+ ++Q D+ ++A + V L LA+VEE ++K+ + L + L
Sbjct: 113 DRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLN 172
Query: 80 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 139
+T + L + + E D + +ER A+Q L EA++ + + L E
Sbjct: 173 STRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLEL 232
Query: 140 RMDQLTNQLKEAR-LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 198
+ + QL++ R +L + +G++ ++ + ++DE + ++R+ S +++LE E +
Sbjct: 233 QRVEAEGQLQQLREVLRQRQEGEAAALN-TVQKLQDERRLLQERLGSLQRALAQLEAEKR 291
Query: 199 VVGNSLKSLE 208
V S LE
Sbjct: 292 EVERSALRLE 301
Score = 55.2 bits (127), Expect = 2e-07
Identities = 48/197 (24%), Positives = 97/197 (49%), Gaps = 17/197 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++K + A + ++ ++ D Q +A ++ + E+V+ L+ ++A +E + + +
Sbjct: 181 LQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQ 240
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L+Q + L +++ E E AALN VQ+++++ +ER G+ Q+ L + + E
Sbjct: 241 LQQLREVLRQRQ------EGEAAALN-TVQKLQDERRLLQERLGSLQRALAQLEAEKREV 293
Query: 124 NRMCKVLEN-----RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
R LE R D+ ++L + RL AE G+ D R L E EL
Sbjct: 294 ERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAE--KGRLD---RTLTGAELELAE 348
Query: 179 AEDRVKSGDAKISELEE 195
A+ +++ +A++ LE+
Sbjct: 349 AQRQIQQLEAQVVVLEQ 365
Score = 48.0 bits (109), Expect = 4e-05
Identities = 54/257 (21%), Positives = 110/257 (42%), Gaps = 13/257 (5%)
Query: 9 QAMKLEKDNAMDKADTCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
Q LE+ +++ Q + + ++A K+ + R L++ L E + + +
Sbjct: 30 QVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRS 89
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
+L+ L+ EA+ AL +V ++ + SE ++GT Q L ++ N +
Sbjct: 90 LEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQ---LTVERL---NGAL 143
Query: 127 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
KV E+ +++ LT L ++ K+ + + L E + +V ++R+ +
Sbjct: 144 AKVEESEGAL-RDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAA 202
Query: 187 DAKISELEEELKVVGNSLKSL--EVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXK 244
+SE ++ +G +++L EV++ + QRVE
Sbjct: 203 RQALSEARKQSSSLGEQVQTLRGEVADLEL-QRVEA-EGQLQQLREVLRQRQEGEAAALN 260
Query: 245 TVKKLQKEVDRLEDELG 261
TV+KLQ E L++ LG
Sbjct: 261 TVQKLQDERRLLQERLG 277
Score = 39.5 bits (88), Expect = 0.013
Identities = 42/245 (17%), Positives = 100/245 (40%), Gaps = 4/245 (1%)
Query: 14 EKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 72
E + A+ DK + ++ ++ LQK L E D + + +L+ A + L
Sbjct: 148 ESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALS 207
Query: 73 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 132
E KQ ++ +V L +V +E ++E + ++ L + Q+ + L++
Sbjct: 208 EARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQD 267
Query: 133 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE-VAEDRVKSGDAKIS 191
+ +ER+ L L + + + + + + + L+ V ++++S + +
Sbjct: 268 ERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTV- 326
Query: 192 ELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQK 251
L E + +L E+ +A +++++ + + +LQ+
Sbjct: 327 RLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQL-ELQQ 385
Query: 252 EVDRL 256
EV+RL
Sbjct: 386 EVERL 390
Score = 37.1 bits (82), Expect = 0.070
Identities = 28/119 (23%), Positives = 56/119 (47%), Gaps = 5/119 (4%)
Query: 38 KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 97
++ E RE+++ ++E+D + + L++ ++ + AE L+R + E
Sbjct: 285 QLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAEL 344
Query: 98 DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
+L +++ + QQ LEAQ E + LE AQQ + + Q +L+ A+ E
Sbjct: 345 ELAEAQRQ---IQQ--LEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTE 398
>AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/d
protein.
Length = 1939
Score = 61.3 bits (142), Expect = 4e-09
Identities = 48/202 (23%), Positives = 106/202 (52%), Gaps = 13/202 (6%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 73
E ++ + +A E++A+ A A + EE+++ Q A +E + KN LEQ KDL+
Sbjct: 1744 EMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MKKN-LEQTVKDLQH 1799
Query: 74 KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
+ + A + + +++Q++E + + E + Q++ +EA + ++ R K L +
Sbjct: 1800 RLDE--AEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQ 1857
Query: 134 AQQD-------EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
++D ++ +D+L ++K + AE+A+ +S+ K ++ ELE AE+R
Sbjct: 1858 TEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIA 1917
Query: 187 DAKISELEEELKVVGNSLKSLE 208
++++++L + + V + S E
Sbjct: 1918 ESQVNKLRVKSREVHTKIISEE 1939
Score = 60.1 bits (139), Expect = 9e-09
Identities = 51/226 (22%), Positives = 110/226 (48%), Gaps = 10/226 (4%)
Query: 4 IKKKMQA---MKLEKDNAMDKAD-TCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDL 57
IK K+Q +K + A D+ + E A+ L E ++ +++ +L+ LA+VE++
Sbjct: 913 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 972
Query: 58 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
+NK++ +++ ++ + E AL QQ +DL+ E++ T + ++ +
Sbjct: 973 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLE 1032
Query: 118 QSADENNRMCKVLENRAQQDEERMD-QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
Q D+ + E + + D ER +L LK A+ A D + ++ KL E E+
Sbjct: 1033 QQVDDLEGSLE-QEKKIRMDLERAKRKLEGDLKLAQESAMDIENDKQQLDEKLKKKEFEM 1091
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSL--EVSEEKANQRVEE 220
+ +++ A +L++++K + ++ L E+ E+A++ E
Sbjct: 1092 SGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAE 1137
Score = 57.6 bits (133), Expect = 5e-08
Identities = 47/261 (18%), Positives = 116/261 (44%), Gaps = 8/261 (3%)
Query: 5 KKKMQAMKLEKDNAMDKADT-CEQQARDANLRAEKVNEEVRELQK---KLAQVEEDLILN 60
+ K + +++ +++A Q+ +DA E VN + L+K +L EDL+++
Sbjct: 1376 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMID 1435
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ A L++K++ AE +K ++ +LE S++ S + +L + + +
Sbjct: 1436 VERTNAACAALDKKQRNFDKILAE---WKQKCEETHAELEASQKESRSLSTELFKIKNAY 1492
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+E+ + L+ + ++ + LT Q+ E + + +V ++ + ++ LE AE
Sbjct: 1493 EESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAE 1552
Query: 181 DRVKSGDAKISELEEELKVVGNSL-KSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
++ + KI ++ EL V + + + + +E+ +Q
Sbjct: 1553 ASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSR 1612
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
+ KK++ +++ +E +L
Sbjct: 1613 NDAIRLKKKMEGDLNEMEIQL 1633
Score = 53.2 bits (122), Expect = 1e-06
Identities = 57/286 (19%), Positives = 124/286 (43%), Gaps = 10/286 (3%)
Query: 1 MDA-IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
+DA I+ + A++L+K D + E Q AN A + R Q L +D L
Sbjct: 1605 LDAEIRSRNDAIRLKKKMEGD-LNEMEIQLNHANRMAAEALRNYRNTQAIL----KDTQL 1659
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
+ L+ A + E+ ++QL E L +++++ LE++E A+Q+LL+A +
Sbjct: 1660 H---LDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASER 1716
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+ L N ++ E + Q+ ++++ A +A+ K+ + A + +EL+
Sbjct: 1717 VQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKE 1776
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXX 238
+D + LE+ +K + + L E ++ + +++++
Sbjct: 1777 QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKR 1836
Query: 239 XXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K +++V L + ++ L D +D A++ Y
Sbjct: 1837 NVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSY 1882
Score = 49.6 bits (113), Expect = 1e-05
Identities = 51/261 (19%), Positives = 115/261 (44%), Gaps = 15/261 (5%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++KM + EK++ + DA R +++ + +L+ K+ +V E
Sbjct: 877 LEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTE----RAED 932
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE-AQQSADE 122
E+ N +L K+++L E E + L + + +E L K E+ + K+ ++ A
Sbjct: 933 EEEINAELTAKKRKL---EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 989
Query: 123 NNRMCKVL-ENRAQQD--EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+ + K+ E +A Q+ ++ +D L + + L + +V +E E ++
Sbjct: 990 DETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIR 1049
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + AK +LE +LK+ S +E +++ ++++++
Sbjct: 1050 MDLER---AK-RKLEGDLKLAQESAMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALG 1105
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
K +K+LQ ++ LE+E+
Sbjct: 1106 MQLQKKIKELQARIEELEEEI 1126
Score = 49.2 bits (112), Expect = 2e-05
Identities = 40/205 (19%), Positives = 95/205 (46%), Gaps = 7/205 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++ + ++ EK +K ++ + K+ +E + LQ+ Q +DL
Sbjct: 958 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAE 1017
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
++K+ K + E+Q+ E + + ++I DLE+++ + + L AQ+SA
Sbjct: 1018 EDKVNTLTKAKIKLEQQVDDLEGSL----EQEKKIRMDLERAKRK---LEGDLKLAQESA 1070
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ + L+ + ++ E M L +++++ + L K E+ ++ +E+E+E
Sbjct: 1071 MDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAER 1130
Query: 181 DRVKSGDAKISELEEELKVVGNSLK 205
+ + S+L EL+ + L+
Sbjct: 1131 ASRAKAEKQRSDLSRELEEISERLE 1155
Score = 48.4 bits (110), Expect = 3e-05
Identities = 50/230 (21%), Positives = 109/230 (47%), Gaps = 15/230 (6%)
Query: 1 MDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
++ K+K++ +KL +++AMD + ++Q D L+ ++ E+ LQ K+ + +
Sbjct: 1052 LERAKRKLEGDLKLAQESAMDIEN--DKQQLDEKLKKKEF--EMSGLQSKIEDEQALGMQ 1107
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER---SGTAQQKLLEA 116
+ K+++ +EE E+++ A A A ++ + +LE+ ER +G A +E
Sbjct: 1108 LQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEM 1167
Query: 117 QQSAD-ENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVED 174
+ + E +M + LE Q E L + ++ L E D V +KL +
Sbjct: 1168 NKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQID-NLQRVKQKLEKEKS 1226
Query: 175 ELEVAEDRVKSGDAKISE----LEEELKVVGNSLKSLEVSEEKANQRVEE 220
E+++ D + S +S+ LE+ + + + L ++ EE+ + + +
Sbjct: 1227 EMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLIND 1276
Score = 47.6 bits (108), Expect = 5e-05
Identities = 30/165 (18%), Positives = 80/165 (48%)
Query: 49 KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 108
K A+ E+++ K + E+ ++L + E + E ++ L ++ ++ ++ +
Sbjct: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLAD 904
Query: 109 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
A+++ + ++ + K + RA+ +EE +LT + ++ + D++
Sbjct: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
Query: 169 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
LA VE E E++VK+ +++ L+E + + K+L+ + ++
Sbjct: 965 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQ 1009
Score = 47.6 bits (108), Expect = 5e-05
Identities = 36/186 (19%), Positives = 84/186 (45%), Gaps = 3/186 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
QQ D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1008 QQTLD-DLQAEE--DKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLK 1064
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
IE D ++ +E+ + ++ Q ++ + L+ + ++ + R+++L
Sbjct: 1065 LAQESAMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEE 1124
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
+++ R A+ + ++SR+L + + LE A + + E E + + L+
Sbjct: 1125 EIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE 1184
Query: 207 LEVSEE 212
+ E
Sbjct: 1185 ATLQHE 1190
Score = 46.0 bits (104), Expect = 2e-04
Identities = 30/184 (16%), Positives = 88/184 (47%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K+ ++ ++Q ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 1732 KKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLE 1791
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LE + +++R + L++
Sbjct: 1792 QTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKV 1851
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + + ++D ++ + +VKS + E EE+ V + + ++ E+A
Sbjct: 1852 KELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAE 1911
Query: 216 QRVE 219
+R +
Sbjct: 1912 ERAD 1915
Score = 43.2 bits (97), Expect = 0.001
Identities = 54/274 (19%), Positives = 118/274 (43%), Gaps = 22/274 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++K +A++ + K + ++ D + ++ E E ++L + ++ L+ ++
Sbjct: 1249 LEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDE-KDTLVSQLSR 1307
Query: 64 LEQA-NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+QA + +EE ++QL +AL +Q D + E+ Q+ E Q++ +
Sbjct: 1308 GKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSK 1367
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
N +V + R + + + + Q T +L+EA+ +KLA L+ AE+
Sbjct: 1368 AN--SEVAQWRTKYETDAI-QRTEELEEAK--------------KKLA---QRLQDAEEH 1407
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXX 242
V++ +AK + LE+ + + N ++ L + E+ N
Sbjct: 1408 VEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEET 1467
Query: 243 XKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
++ QKE L EL K+ Y+ D++++
Sbjct: 1468 HAELEASQKESRSLSTELFKIKNAYEESLDQLET 1501
Score = 41.9 bits (94), Expect = 0.002
Identities = 53/221 (23%), Positives = 101/221 (45%), Gaps = 31/221 (14%)
Query: 24 TCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDLIL---NKNKLE---QAN----KDL 71
+ E + AN++ E K EE+ + + K ++EE ++ KN L+ QA D
Sbjct: 846 SAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADA 905
Query: 72 EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE 131
EE+ QL T+ ++ A K++++ E E EE + K + + E + LE
Sbjct: 906 EERCDQLIKTKIQLEA---KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 962
Query: 132 NRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR----KLAFVE------DELEVAED 181
+ E+ N++K L E+ G + +++ K A E D+L+ ED
Sbjct: 963 LTLAKVEKEKHATENKVKN---LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEED 1019
Query: 182 RVKSGDAKISELEEELKVVGNSL---KSLEVSEEKANQRVE 219
+V + +LE+++ + SL K + + E+A +++E
Sbjct: 1020 KVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLE 1060
Score = 39.1 bits (87), Expect = 0.017
Identities = 30/161 (18%), Positives = 81/161 (50%), Gaps = 9/161 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ +KK ++ + + +D+A+ + + + +K+ VREL+ +VE + N
Sbjct: 1783 LERMKKNLEQTVKDLQHRLDEAE--QLALKGGKKQIQKLEARVRELE---GEVESEQKRN 1837
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
++ K E K K+LT E + + ++++ ++K + + + +++ EA++ +
Sbjct: 1838 VEAVKGLRKH-ERKVKELTYQTEED---RKNILRLQDLVDKLQAKVKSYKRQAEEAEEQS 1893
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
+ N + +++ ++ EER D +Q+ + R+ + + K
Sbjct: 1894 NVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVHTK 1934
>AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein.
Length = 1088
Score = 61.3 bits (142), Expect = 4e-09
Identities = 47/224 (20%), Positives = 101/224 (45%), Gaps = 5/224 (2%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++K+ ++ + +N ++ E+Q R + + + L +EE L
Sbjct: 538 LDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEK 597
Query: 61 KNKL----EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+ + EQ ++D EK++++ + ++ L KV ++ DL + E ++
Sbjct: 598 ERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSL 657
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
S + + K LE +Q +E ++ +QLK+A A +A S E+S ++ +E E+
Sbjct: 658 ASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARA-SPEMSDRIQHLEREI 716
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+D A++ L E LK V N + + ++V++
Sbjct: 717 TRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKD 760
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/254 (16%), Positives = 110/254 (43%), Gaps = 7/254 (2%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
E + ++ +++ L +EE++ + K+ + ++ EE+ KQ+ + + K+ Q++
Sbjct: 385 EMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVK 444
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
++L + + Q KL ++ + +VL+ E+R L ++ RL E
Sbjct: 445 QELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE 504
Query: 157 DADGKSDEVSRKLAFVED-------ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 209
+ + ++ ++++ + + E+ +D + + K++ L+++++ + L+ E
Sbjct: 505 EKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEK 564
Query: 210 SEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKS 269
+RV+ +T+++L+++ DR E E D YK
Sbjct: 565 QMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKK 624
Query: 270 LADEMDSTFAELAG 283
++ + L G
Sbjct: 625 DLKDLKEKVSLLQG 638
Score = 48.8 bits (111), Expect = 2e-05
Identities = 51/210 (24%), Positives = 97/210 (46%), Gaps = 15/210 (7%)
Query: 13 LEKDNAMDKADTCEQQARDANLRA--EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKD 70
LE++ K ++ + QA L ++V E + KK+A++E + ++NK K
Sbjct: 712 LEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQ-VKDQNKKVANLKH 770
Query: 71 LEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
E+ EK+ +A E A LN QQ+++ L K ++R ++ L E+ Q E
Sbjct: 771 KEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREM 830
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
+ E+ E+++++L +++ + E K + LA E E + R +
Sbjct: 831 VLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLA--EKETHLTNLRAE- 887
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKAN 215
+ LEE L++ +L + +SE+ AN
Sbjct: 888 ---RRKHLEEVLEMKQEALLAA-ISEKDAN 913
Score = 45.6 bits (103), Expect = 2e-04
Identities = 44/227 (19%), Positives = 91/227 (40%), Gaps = 11/227 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K+++ E K +T Q D+ E + E + +++ A ++ ++ + +
Sbjct: 443 VKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLR 502
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
LE+ L +K KQ+ E ++ +++ L+ E + Q+K+ Q+ +
Sbjct: 503 LEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDK 562
Query: 124 NRMCKVLENRA---QQDEERMDQLTNQLKEA--------RLLAEDADGKSDEVSRKLAFV 172
+ L+ R Q D D L+EA L E D E ++
Sbjct: 563 EKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNY 622
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ +L+ +++V +SE E L + SL S K + R++
Sbjct: 623 KKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLK 669
Score = 41.9 bits (94), Expect = 0.002
Identities = 46/261 (17%), Positives = 112/261 (42%), Gaps = 13/261 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D KK ++ +K EK + + + D E++A +L+ + L+K ++ L
Sbjct: 619 IDNYKKDLKDLK-EKVSLL-QGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALE 676
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAA-LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
+ K E + + K+ A EA + ++ ++Q +E ++ + ++ S AQ ++
Sbjct: 677 QKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEV------ 730
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
D + K +EN ++++ +L Q+K+ + K +K A + +E
Sbjct: 731 -DRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRR 789
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
ED + +L++ L+ + ++ LE + ++ Q E
Sbjct: 790 EDNLNDSS---QQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQV 846
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
++K+++E++ ++ +L
Sbjct: 847 EELLMAMEKVKQELESMKAKL 867
Score = 39.9 bits (89), Expect = 0.010
Identities = 46/206 (22%), Positives = 87/206 (42%), Gaps = 9/206 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D + + ++ ++ EK++ K E+Q +D N + + + + +KK AQ+ E+
Sbjct: 730 VDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRR 789
Query: 61 KNKLEQANKDLEEK-EKQLTATEAEVAALNRKVQ-QIEEDLEKSEERSGTAQ-----QKL 113
++ L +++ L++ K+ E AL VQ E ++ ++E S ++L
Sbjct: 790 EDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEEL 849
Query: 114 LEAQQSADENNRMCKVLENRAQQD-EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 172
L A + + K + QQ E+ LTN E R E+ E + A
Sbjct: 850 LMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQE-ALLAAIS 908
Query: 173 EDELEVAEDRVKSGDAKISELEEELK 198
E + +A + S K E LK
Sbjct: 909 EKDANIALLELSSSKKKTQEEVAALK 934
Score = 38.7 bits (86), Expect = 0.023
Identities = 31/170 (18%), Positives = 77/170 (45%), Gaps = 3/170 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q +A R + +N+ ++LQ L + ++ + + L ++ + E+E L E+
Sbjct: 781 QMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESART 840
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
++V+++ +EK ++ + + KL QQS E L ++ E + ++
Sbjct: 841 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQ 900
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 196
+ A + +DA+ E+S ++E+ + + D + +L+++
Sbjct: 901 EALLAAISEKDANIALLELSSSKKKTQEEVAALK---REKDRLVQQLKQQ 947
Score = 37.1 bits (82), Expect = 0.070
Identities = 44/185 (23%), Positives = 86/185 (46%), Gaps = 23/185 (12%)
Query: 36 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI 95
AE E + L + + ++L L + K LEE E ++ E + LN + + I
Sbjct: 260 AELTEENFQRLHAEHERQAKELFLLR-------KTLEEMELRI---ETQKQTLNARDESI 309
Query: 96 EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL-KEARLL 154
++ LE Q K L A+ + +++ R ++ E A+ ++ L Q KE +L
Sbjct: 310 KKLLE-------MLQSKGLSAKATEEDHERTRRLAE--AEMHVHHLESLLEQKEKENSML 360
Query: 155 AEDADGKSDEV--SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV-GNSLKSLEVSE 211
E+ + + S K ++ +E+ + ++ S + + +LEEE++++ N S E E
Sbjct: 361 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE 420
Query: 212 EKANQ 216
E+ Q
Sbjct: 421 EEMKQ 425
>AB007914-1|BAA32290.2| 1919|Homo sapiens KIAA0445 protein protein.
Length = 1919
Score = 61.3 bits (142), Expect = 4e-09
Identities = 44/190 (23%), Positives = 91/190 (47%), Gaps = 2/190 (1%)
Query: 20 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 79
D+ D+ ++Q D+ ++A + V L LA+VEE ++K+ + L + L
Sbjct: 1586 DRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLN 1645
Query: 80 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 139
+T + L + + E D + +ER A+Q L EA++ + + L E
Sbjct: 1646 STRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLEL 1705
Query: 140 RMDQLTNQLKEAR-LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 198
+ + QL++ R +L + +G++ ++ + ++DE + ++R+ S +++LE E +
Sbjct: 1706 QRVEAEGQLQQLREVLRQRQEGEAAALN-TVQKLQDERRLLQERLGSLQRALAQLEAEKR 1764
Query: 199 VVGNSLKSLE 208
V S LE
Sbjct: 1765 EVERSALRLE 1774
Score = 55.6 bits (128), Expect = 2e-07
Identities = 58/263 (22%), Positives = 121/263 (46%), Gaps = 23/263 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++K + A + ++ ++ D Q +A ++ + E+V+ L+ ++A +E + + +
Sbjct: 1654 LQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQ 1713
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L+Q + L +++ E E AALN VQ+++++ +ER G+ Q+ L + + E
Sbjct: 1714 LQQLREVLRQRQ------EGEAAALN-TVQKLQDERRLLQERLGSLQRALAQLEAEKREV 1766
Query: 124 NRMCKVLEN-----RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
R LE R D+ ++L + RL AE G+ D R L E EL
Sbjct: 1767 ERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAE--KGRLD---RTLTGAELELAE 1821
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEV-SEEKANQRVEEFXXXXXXXXXXXXXXXX 237
A+ +++ +A++ LE+ +S LEV ++++ + +E
Sbjct: 1822 AQRQIQQLEAQVVVLEQ-----SHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEA 1876
Query: 238 XXXXXXKTVKKLQKEVDRLEDEL 260
+ V+ L+++V L+ +L
Sbjct: 1877 RERAHRQRVRGLEEQVSTLKGQL 1899
Score = 53.6 bits (123), Expect = 8e-07
Identities = 53/223 (23%), Positives = 105/223 (47%), Gaps = 20/223 (8%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 65
+++++ + E+D + +Q + + R+LQK +A+ EE +L
Sbjct: 1418 QELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLS 1477
Query: 66 --QANKDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
QA L+E+ E++ AT +VA L R +Q E +L S+E+ ++ K E +
Sbjct: 1478 GVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEK--ISKMKANETKL 1535
Query: 119 SADENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
D+ R+ +VL E+R + E + L +L+ +RL G SD ++ A ++D
Sbjct: 1536 EGDK-RRLKEVLDASESRTVKLELQRRSLEGELQRSRL------GLSDREAQAQA-LQDR 1587
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
++ + +V + K L+ ++ + +L +E SE +V
Sbjct: 1588 VDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKV 1630
Score = 49.6 bits (113), Expect = 1e-05
Identities = 41/216 (18%), Positives = 91/216 (42%), Gaps = 4/216 (1%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ + + EK N +QQA + EK+ EL+++ ++EE+
Sbjct: 496 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 555
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ ++LE +QL E + + L +++ ++ E L ++ + Q + E ++ +
Sbjct: 556 GARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKA 615
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
LE + L + L + L E +++R +A +E+E + R
Sbjct: 616 EAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQ 675
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ + + + EE + L+ L + +E A Q +E
Sbjct: 676 RQAEQEATVAREEQE----RLEELRLEQEVARQGLE 707
Score = 47.2 bits (107), Expect = 7e-05
Identities = 52/218 (23%), Positives = 94/218 (43%), Gaps = 9/218 (4%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL---AQVEEDLILNKNK 63
++Q M+ + + D T +Q D+ + E+++ L+ K Q ED +
Sbjct: 436 QVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQR 495
Query: 64 LEQANKDLEEKEKQLTATEAEVAALN-RKVQQIEEDLEKSEERSGTAQQKLLEAQQSA-D 121
L AN +L +EK A +VA +++Q E L+ ++E + +L E Q+ A
Sbjct: 496 LRSAN-ELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQ 554
Query: 122 ENNRMCKVLE---NRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
+ R+ + LE + +Q E + L +L E R A + D + + A V + L
Sbjct: 555 DGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTK 614
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
AE + +++L E + +SL L E Q
Sbjct: 615 AEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQ 652
Score = 46.4 bits (105), Expect = 1e-04
Identities = 43/196 (21%), Positives = 90/196 (45%), Gaps = 14/196 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A+ +++ M+ E+D+A +A ++ ++ V+ + +Q +LA EE + ++
Sbjct: 1436 ALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSER 1495
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQI---EEDLEKSEER------SGTAQQKL 113
+ + E+ L ATE+E+ A K+ ++ E LE + R + ++
Sbjct: 1496 ERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVK 1555
Query: 114 LEAQQSADENNRMCKVL-----ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
LE Q+ + E L E +AQ ++R+D L Q+ ++ + A + ++
Sbjct: 1556 LELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGA 1615
Query: 169 LAFVEDELEVAEDRVK 184
LA VE+ D+V+
Sbjct: 1616 LAKVEESEGALRDKVR 1631
Score = 45.2 bits (102), Expect = 3e-04
Identities = 52/230 (22%), Positives = 107/230 (46%), Gaps = 18/230 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQA-RDANLRAEKVNEEV--RELQKKLAQVEEDLIL 59
++ K++ A KL + +A EQ+A + +L+ + +E REL+ + AQ++ L
Sbjct: 865 SLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQR 924
Query: 60 NKNKL-EQANKDLEEKEKQLTATEAEV-AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
+ +L + + EE +++ A + E L + ++ L E +KL+ +
Sbjct: 925 EQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTR 984
Query: 118 QSAD----ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
S E R + ++R +QD ++ LT++L++ R E+A + R+L
Sbjct: 985 HSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQ--- 1041
Query: 174 DELEVAEDRVKSGDAKISELEE---ELKVVGNSLKSLEVSEEKANQRVEE 220
E A D K D+ + E EE +L+++ ++ L +A +++ E
Sbjct: 1042 ---EQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRE 1088
Score = 44.4 bits (100), Expect = 5e-04
Identities = 52/221 (23%), Positives = 97/221 (43%), Gaps = 21/221 (9%)
Query: 8 MQAMKLEKDNAMDKADT--CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 65
+QA K E A+ KA+ E + LRAE+ + +++ KL+ + E L +K L
Sbjct: 601 LQAEKAEVAEALTKAEAGRVELELSMTKLRAEEAS--LQDSLSKLSALNESLAQDKLDLN 658
Query: 66 QANKDLEEKEKQLTA----TEAEVAALNRKVQQIEE-DLEKSEERSGTAQQKLLEAQQSA 120
+ LEE++ L E E + +++EE LE+ R G + L A+Q+
Sbjct: 659 RLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQG-LEGSLRVAEQAQ 717
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ + L + Q +E++ QL+ QL G+ E+ + + ++E E
Sbjct: 718 EALEQQLPTLRHERSQLQEQLAQLSRQL----------SGREQELEQARREAQRQVEALE 767
Query: 181 DRVKSGDAKISE-LEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ +A E +++V + +SEE R+E+
Sbjct: 768 RAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEK 808
Score = 43.6 bits (98), Expect = 8e-04
Identities = 45/199 (22%), Positives = 88/199 (44%), Gaps = 11/199 (5%)
Query: 26 EQQARDANLRAEK----VNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT 81
E+Q RDA R E+ VN EL+ AQ EE + ++ + + + KQ +
Sbjct: 995 ERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSC 1054
Query: 82 EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
E L +++ +E+ + AQ+KL E+Q+ + + L + +
Sbjct: 1055 LREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKER 1114
Query: 142 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 201
+ L +E R + A+ S+ +S KLA + E ++A ++ + + EL+
Sbjct: 1115 EALRRSNEELRSAVKKAE--SERISLKLANEDKEQKLA--LLEEARTAVGKEAGELR--- 1167
Query: 202 NSLKSLEVSEEKANQRVEE 220
L+ +E S +A + ++E
Sbjct: 1168 TGLQEVERSRLEARRELQE 1186
Score = 41.1 bits (92), Expect = 0.004
Identities = 40/219 (18%), Positives = 102/219 (46%), Gaps = 10/219 (4%)
Query: 5 KKKMQAMKLEKDNA---MDKADTCEQQARDA-NLRAEKVNEEVRELQKKLAQVEEDLILN 60
+++++ ++LE++ A ++ + +QA++A + + E +LQ++LAQ+ L
Sbjct: 689 QERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGR 748
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +LEQA ++ + + + L E AL ++ + L +E T ++ +
Sbjct: 749 EQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEK 808
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ ++ + Q E R +QL + + L E G+ + +++ +++ + +
Sbjct: 809 EALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDK 868
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ + K+ + E E + SL+ + E+ QR++
Sbjct: 869 ELMAQ---KLVQAEREAQA---SLREQRAAHEEDLQRLQ 901
Score = 40.7 bits (91), Expect = 0.006
Identities = 42/210 (20%), Positives = 88/210 (41%), Gaps = 13/210 (6%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+ ++++ + ++ ++ + D E++ DA +V E+ ++L Q+E +
Sbjct: 522 EELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLA 581
Query: 62 NKLEQANKDLEEKEKQ---LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
+L + + L Q L A +AEVA K + +LE S KL +
Sbjct: 582 KELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELS-------MTKLRAEEA 634
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
S ++ L QD+ +++L QL+E + + G+ + ++ +E E
Sbjct: 635 SLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQ---GRQRQAEQEATVAREEQER 691
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLE 208
E+ + LE L+V + ++LE
Sbjct: 692 LEELRLEQEVARQGLEGSLRVAEQAQEALE 721
Score = 39.5 bits (88), Expect = 0.013
Identities = 42/245 (17%), Positives = 100/245 (40%), Gaps = 4/245 (1%)
Query: 14 EKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 72
E + A+ DK + ++ ++ LQK L E D + + +L+ A + L
Sbjct: 1621 ESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALS 1680
Query: 73 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 132
E KQ ++ +V L +V +E ++E + ++ L + Q+ + L++
Sbjct: 1681 EARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQD 1740
Query: 133 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE-VAEDRVKSGDAKIS 191
+ +ER+ L L + + + + + + + L+ V ++++S + +
Sbjct: 1741 ERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTV- 1799
Query: 192 ELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQK 251
L E + +L E+ +A +++++ + + +LQ+
Sbjct: 1800 RLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQL-ELQQ 1858
Query: 252 EVDRL 256
EV+RL
Sbjct: 1859 EVERL 1863
Score = 37.9 bits (84), Expect = 0.040
Identities = 52/227 (22%), Positives = 106/227 (46%), Gaps = 19/227 (8%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+A+ K+ + ++ A + T ++A L E + + E+Q++LAQ+E +
Sbjct: 774 EALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLE----ARR 829
Query: 62 NKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIEEDL-EKSEERSGTAQQKLLEA 116
+LE + L E +L ++ A K +E + +K + AQ L E
Sbjct: 830 EQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQ 889
Query: 117 QQSADEN-NRMCKVLENRAQQDEERMDQLTNQL-KEARLLAEDADGKSDEVSRKLAFVED 174
+ + +E+ R+ + E ++ E QL +QL +E L + + +E+S ++A ++
Sbjct: 890 RAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQ 949
Query: 175 E----LEVAE-DRVKSGDAKISE---LEEELKVVGNSLKSLEVSEEK 213
E L +AE ++ ++ K SE L E+L +SL ++ + E+
Sbjct: 950 ERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMER 996
Score = 37.5 bits (83), Expect = 0.053
Identities = 38/166 (22%), Positives = 82/166 (49%), Gaps = 11/166 (6%)
Query: 46 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 105
L K+ QV++ + + E + L KQL+ +E+E AL ++Q++ + + + +
Sbjct: 430 LHKRQLQVQD----MRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQA 485
Query: 106 SGTAQ---QKLLEAQQ--SADENN--RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA 158
AQ Q+L A + S +++N +V + +A++ + ++L +E R +
Sbjct: 486 HEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRL 545
Query: 159 DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL 204
+ + ++ + A V ELE + +++ + K S L +EL V +L
Sbjct: 546 EEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREAL 591
Score = 36.3 bits (80), Expect = 0.12
Identities = 44/217 (20%), Positives = 97/217 (44%), Gaps = 19/217 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++ + ++++ A + + + A++ + NEE+R KK E + I
Sbjct: 1086 LRESQEGREVQRQEAGELRRSLGEGAKEREA-LRRSNEELRSAVKK---AESERI----S 1137
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L+ AN+D KE++L E A+ ++ ++ L++ E + LEA++ E
Sbjct: 1138 LKLANED---KEQKLALLEEARTAVGKEAGELRTGLQEVE-------RSRLEARRELQEL 1187
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
R K+L++ + + +L +L +++ ++ + ++L E LEV +
Sbjct: 1188 RRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQEL 1247
Query: 184 KSGDAKISELEEELKV-VGNSLKSLEVSEEKANQRVE 219
+ K+ E E E + L SLE + Q+++
Sbjct: 1248 QVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLD 1284
Score = 36.3 bits (80), Expect = 0.12
Identities = 31/166 (18%), Positives = 69/166 (41%), Gaps = 4/166 (2%)
Query: 47 QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS 106
++KLA +EE + + L+E E+ E+ L R+++ ++ + +
Sbjct: 1146 EQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGREL 1205
Query: 107 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 166
Q +L +++ E+ R L R + E ++ + +L+ A+ ++ +G+
Sbjct: 1206 AELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRE 1265
Query: 167 RKLAFVEDELEVAE----DRVKSGDAKISELEEELKVVGNSLKSLE 208
R+L +E E D + + K+ E +G L + E
Sbjct: 1266 RRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAE 1311
Score = 33.5 bits (73), Expect = 0.86
Identities = 27/130 (20%), Positives = 60/130 (46%), Gaps = 2/130 (1%)
Query: 52 QVEEDLILNKNKLE-QANKDLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTA 109
++E+ L L +LE Q + L + +L + E A+ RK+Q +E ++ +
Sbjct: 19 RLEQALRLEPGELETQEPRGLVRQSVELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQRL 78
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
Q K+L+ ++ E + +Q R + + L+ A + E+ +S +++
Sbjct: 79 QGKILQYKKRCSELEQQLLERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQVN 138
Query: 170 AFVEDELEVA 179
A + ++L+ A
Sbjct: 139 AMLREQLDQA 148
>X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain (1437
AA) protein.
Length = 1437
Score = 60.9 bits (141), Expect = 5e-09
Identities = 44/208 (21%), Positives = 106/208 (50%), Gaps = 9/208 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ + ++ E + + ++ E++A+ A A + EE+++ Q A +E + KN
Sbjct: 1233 LENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MKKN- 1288
Query: 64 LEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
LEQ KDL E ++ L + ++ L +V+++E ++E ++R+ A + L + ++
Sbjct: 1289 LEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHER 1348
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
E + + ++ +D+L ++K + AE+A+ +S+ K ++ ELE
Sbjct: 1349 RVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEE 1408
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKS 206
AE+R ++++++L + + V + +
Sbjct: 1409 AEERADIAESQVNKLRVKSREVHTKISA 1436
Score = 58.0 bits (134), Expect = 3e-08
Identities = 60/278 (21%), Positives = 127/278 (45%), Gaps = 19/278 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEK-VNEEVRELQKKLAQVEEDLILNKN 62
++K+ +K+E D+ A+ + + + + ++V EL+ K + E+ ++N
Sbjct: 719 LEKEKSELKMETDDLSSNAEAISKAKGNLEKDGGRSLEDQVSELKTK--EEEQQRLINDL 776
Query: 63 KLEQANKDLE--EKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQQKLLEA 116
++A E E +QL +A V+ L+R QQIEE + EE + A+ L A
Sbjct: 777 TAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEET-KAKNALAHA 835
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
QS+ + C +L + ++++E +L L +A +E A +++ + + E EL
Sbjct: 836 LQSSRHD---CDLLREQYEEEQEGKAELQRALSKAN--SEVAQWRTNTETDAIQRTE-EL 889
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXX 236
E A+ ++ ++ E EE ++ V SLE ++++ VE+
Sbjct: 890 EEAKKKLAQ---RLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALD 946
Query: 237 XXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
K + + +++ + + EL ++ +SL+ E+
Sbjct: 947 KKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTEL 984
Score = 55.6 bits (128), Expect = 2e-07
Identities = 54/262 (20%), Positives = 114/262 (43%), Gaps = 20/262 (7%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE----QANK 69
E D+ D + CEQ ++ ++ E +EV E ++ ++ +L K KLE + K
Sbjct: 396 EADSLADAEERCEQLIKN-KIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKK 454
Query: 70 DLEEKE-------KQLTATEAEVAALNRKVQQIEEDLEK-SEERSG---TAQQKLLEAQQ 118
D+++ E K+ ATE +V L ++ ++E + K S+E+ T QQ L + Q
Sbjct: 455 DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQA 514
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
D+ N +L + E+++D L L++ + L D + ++ L ++
Sbjct: 515 EEDKVN----ILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMD 570
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXX 238
E+ + D K+ + E E+ + + ++ + E + ++++E
Sbjct: 571 NENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERAS 630
Query: 239 XXXXXKTVKKLQKEVDRLEDEL 260
K L +E++ + + L
Sbjct: 631 RAKAEKQRSDLSRELEEISERL 652
Score = 51.6 bits (118), Expect = 3e-06
Identities = 47/285 (16%), Positives = 118/285 (41%), Gaps = 1/285 (0%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ ++ + A +++A+ E + ++ N E + + L
Sbjct: 1097 VETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKET 1156
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ L+ A + E+ ++QL E L +++++ LE++E A+Q+LL+A +
Sbjct: 1157 QLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERV 1216
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L N ++ E + QL ++++E + +A+ K+ + A + +EL+ +
Sbjct: 1217 QLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQ 1276
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + LE+ +K + + L E ++ + +++++
Sbjct: 1277 DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRN 1336
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K ++ V L + ++ L D +D A++ Y
Sbjct: 1337 AEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSY 1381
Score = 49.2 bits (112), Expect = 2e-05
Identities = 29/165 (17%), Positives = 80/165 (48%)
Query: 49 KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 108
K A+ E+++ K + ++ +L + E + E ++ L ++ ++ ++ +
Sbjct: 343 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 402
Query: 109 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
A+++ + ++ + K + RA+++EE +LT + ++ + D++
Sbjct: 403 AEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELT 462
Query: 169 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
LA VE E E++VK+ +++ L+E + + K+L+ + ++
Sbjct: 463 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQ 507
Score = 48.4 bits (110), Expect = 3e-05
Identities = 33/184 (17%), Positives = 88/184 (47%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K+ +V +LQ ++ +V ++ + K ++A D ++L + A L R + +E
Sbjct: 1231 KKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLE 1290
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LE + +++R + L++
Sbjct: 1291 QTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRV 1350
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + + ++D ++ + +VKS + E EE+ + + L+ E+A
Sbjct: 1351 KELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAE 1410
Query: 216 QRVE 219
+R +
Sbjct: 1411 ERAD 1414
Score = 47.2 bits (107), Expect = 7e-05
Identities = 62/279 (22%), Positives = 121/279 (43%), Gaps = 25/279 (8%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ-------KKLAQVE--- 54
+K+M MK E D+ E + ++ + + +E +LQ LA E
Sbjct: 348 EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERC 407
Query: 55 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
E LI NK +LE K++ E+ ++ AE+ A RK++ +L+K + K +
Sbjct: 408 EQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAK-V 466
Query: 115 EAQQSADENNRMCKVLENRAQQDE--ERMDQLTNQLKEA-RLLAEDADGKSDEVS----- 166
E ++ A E N++ + E A DE ++ + L+E + +D + D+V+
Sbjct: 467 EKEKHATE-NKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKA 525
Query: 167 -RKLAFVEDELEVAEDRVKSGDAKIS----ELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
KL D+LE + ++ K + +LE +LK+ S E +++ ++++E+
Sbjct: 526 KTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDNENDKQQLDEKLEKK 585
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
K +K+LQ ++ L +E+
Sbjct: 586 EFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEI 624
Score = 45.6 bits (103), Expect = 2e-04
Identities = 36/205 (17%), Positives = 95/205 (46%), Gaps = 7/205 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++ + ++ EK +K ++ + K+++E + LQ+ Q +DL
Sbjct: 456 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAE 515
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
++K+ K + E+Q+ E + + +++ DLE+++ + + L AQ+S
Sbjct: 516 EDKVNILTKAKTKLEQQVDDLEGSL----EQEKKLRMDLERAKRK---LEGDLKLAQEST 568
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+N + L+ + ++ E + L +++++ + + K E+ ++ + +E+E
Sbjct: 569 MDNENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAER 628
Query: 181 DRVKSGDAKISELEEELKVVGNSLK 205
+ + S+L EL+ + L+
Sbjct: 629 ASRAKAEKQRSDLSRELEEISERLE 653
Score = 45.6 bits (103), Expect = 2e-04
Identities = 46/209 (22%), Positives = 97/209 (46%), Gaps = 15/209 (7%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+Q+ D + + +++ EL+K QVE++ + LE+A LE +E ++ + E+
Sbjct: 1009 QQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLEL 1068
Query: 86 ----AALNRKVQQIEED---LEKSEERSGTAQQKLLEAQ-QSADENNRMCKVLENRAQQD 137
+ ++RK+ + +E+ L+++ R Q L+A+ +S ++ R+ K +E +
Sbjct: 1069 NQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEM 1128
Query: 138 EERMDQLTNQLKEARLLAEDADG-------KSDEVSRKLAFVEDELEVAEDRVKSGDAKI 190
E +++ E+ + G D+ R ++++L + E R A+I
Sbjct: 1129 EIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEI 1188
Query: 191 SELEEELKVVGNSLKSLEVSEEKANQRVE 219
EL L+ S K E A++RV+
Sbjct: 1189 EELWATLEQTERSRKIAEQELLDASERVQ 1217
Score = 43.6 bits (98), Expect = 8e-04
Identities = 37/178 (20%), Positives = 72/178 (40%), Gaps = 3/178 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
QQ + + E+ + L L D L + + E+ + E ++ L+ +EVA
Sbjct: 813 QQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVA 872
Query: 87 A--LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQL 144
N + I+ E+ EE Q+L EA++ + N C LE Q+ + ++ L
Sbjct: 873 QWRTNTETDAIQRT-EELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDL 931
Query: 145 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 202
++ + D K + L+ + + E + +++ + L EL V N
Sbjct: 932 MLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKN 989
Score = 42.3 bits (95), Expect = 0.002
Identities = 46/209 (22%), Positives = 95/209 (45%), Gaps = 14/209 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+ K+ +A++ +D E + K+ ++V +L+ L Q E+ L ++
Sbjct: 494 LSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQ-EKKLRMD--- 549
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
LE+A + LE K A E+ + N K QQ++E LEK E K+ E +Q+ +
Sbjct: 550 LERAKRKLEGDLK--LAQESTMDNENDK-QQLDEKLEKKEFEISNLISKI-EDEQAVEIQ 605
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
L+ + ++ + R+++L +++ R A+ + ++SR+L + + LE A
Sbjct: 606 ------LQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 659
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEE 212
+ + E E + + L+ + E
Sbjct: 660 SAQVELNKKREAEFQKLRRDLEEATLQHE 688
Score = 41.5 bits (93), Expect = 0.003
Identities = 47/216 (21%), Positives = 102/216 (47%), Gaps = 13/216 (6%)
Query: 14 EKDNAMDKADT-CEQQARD--ANLRAEK-----VNEEVRELQKKLAQVEEDLILNKNKLE 65
+K N + KA T EQQ D +L EK + R+L+ L +E + N+N +
Sbjct: 517 DKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDNENDKQ 576
Query: 66 QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
Q ++ LE+KE +++ +++ Q+++ +++ + R +++ + S + +
Sbjct: 577 QLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEK 636
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL--AFVEDELEVAEDRV 183
L ++ ER+++ L + + + ++ R L A ++ E VA R
Sbjct: 637 QRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRK 696
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
K D+ ++EL E++ + + LE +EK+ ++E
Sbjct: 697 KHADS-MAELGEQIDNLQRVKQKLE--KEKSELKME 729
Score = 38.7 bits (86), Expect = 0.023
Identities = 51/259 (19%), Positives = 100/259 (38%), Gaps = 10/259 (3%)
Query: 9 QAMKLEKDNAMDKADTCEQQA--RDANLRAEKVNEEVRELQKKLAQVEEDL---ILNKN- 62
Q +LEK + + CE QA +A E ++ +Q +L QV+ ++ I K+
Sbjct: 1025 QIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE 1084
Query: 63 KLEQANKDLEEKEKQLTAT-EAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
+++Q ++ + + +T +AE+ + N R +++E DL + E + A + E+ +
Sbjct: 1085 EIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLR 1144
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
+ + K + + L QL A + +E+ L E ++
Sbjct: 1145 NYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKI 1204
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXX 238
AE + ++ L + + N+ K LE + VEE
Sbjct: 1205 AEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITD 1264
Query: 239 XXXXXKTVKKLQKEVDRLE 257
+ +KK Q LE
Sbjct: 1265 AAMMAEELKKEQDTSAHLE 1283
Score = 38.3 bits (85), Expect = 0.030
Identities = 48/219 (21%), Positives = 96/219 (43%), Gaps = 23/219 (10%)
Query: 21 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILNKNKLE---QANKD-LEE 73
K+ E++ +K +E+ + + K ++EE L+ KN L+ Q+ D L +
Sbjct: 343 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 402
Query: 74 KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
E++ L K++++ E E+ EE + K + + E + LE
Sbjct: 403 AEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELT 462
Query: 134 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR----KLAFVE------DELEVAEDRV 183
+ E+ N++K L E+ G + +++ K A E D+L+ ED+V
Sbjct: 463 LAKVEKEKHATENKVKN---LTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKV 519
Query: 184 KSGDAKISELEEELKVVGNSL---KSLEVSEEKANQRVE 219
++LE+++ + SL K L + E+A +++E
Sbjct: 520 NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLE 558
Score = 30.3 bits (65), Expect = 8.0
Identities = 34/146 (23%), Positives = 67/146 (45%), Gaps = 18/146 (12%)
Query: 14 EKDNAMDKA-DTCEQQARDANLRAEKVNEEVRELQKKLAQVE---EDLILNKNKLEQANK 69
+K DK +Q+ + E +E R L +L +V+ E+ + L + NK
Sbjct: 947 KKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENK 1006
Query: 70 DLEEKEKQLTATEAE----VAALNRKVQQIEED-------LEKSEERSGTAQQKLLEAQQ 118
+L+++ LT AE + L + +Q+E++ LE++E + K+L Q
Sbjct: 1007 NLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQL 1066
Query: 119 SADENNRMCKVLENRAQQDEERMDQL 144
E N++ ++ + + +E +DQL
Sbjct: 1067 ---ELNQVKSEVDRKIAEKDEEIDQL 1089
>BC118982-1|AAI18983.1| 553|Homo sapiens KIAA2012 protein protein.
Length = 553
Score = 60.9 bits (141), Expect = 5e-09
Identities = 54/186 (29%), Positives = 92/186 (49%), Gaps = 14/186 (7%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+++A LRAE+ E++KK + EE L + +LE+A K EE E + E+
Sbjct: 353 QEKASWDRLRAERAEMRWLEVEKKRREQEEQRQLQQEQLERAKKMEEELELEQQRRTEEI 412
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLE--AQQSADENNRMCKVLENRAQQDE----- 138
+++Q+ E+ ++ EER + K + A+Q +E R + L+ + QQ+E
Sbjct: 413 RLRKQRLQE-EQQRQEEEERKQQLRLKAAQERARQQQEEFRRKLRELQRKKQQEEAERAE 471
Query: 139 ---ERMDQLTNQL-KEARLLAEDADGKSDEVSRKLAFVEDE--LEVAEDRVKSGDAKISE 192
+R ++L QL +E + L E A+ + E R+ E++ LE E R K +A
Sbjct: 472 AEKQRQEELEMQLEEEQKHLMEMAEEERLEYQRRKQEAEEKARLEAEERRQKEEEAARLA 531
Query: 193 LEEELK 198
LEE K
Sbjct: 532 LEEATK 537
Score = 44.0 bits (99), Expect = 6e-04
Identities = 44/178 (24%), Positives = 84/178 (47%), Gaps = 23/178 (12%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN---------EEVRELQKKLAQVEE 55
++++Q +LE+ M++ EQQ R +R K EE R+ Q +L +E
Sbjct: 383 QRQLQQEQLERAKKMEEELELEQQRRTEEIRLRKQRLQEEQQRQEEEERKQQLRLKAAQE 442
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER-SGTAQQKLL 114
+ + + ++L+ K++Q A AE A ++ +++E LE+ ++ A+++ L
Sbjct: 443 RARQQQEEFRRKLRELQRKKQQEEAERAE--AEKQRQEELEMQLEEEQKHLMEMAEEERL 500
Query: 115 EAQQSADENNRMCKV-LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
E Q+ E ++ E R Q++EE ARL E+A ++ E +R F
Sbjct: 501 EYQRRKQEAEEKARLEAEERRQKEEEA----------ARLALEEATKQAQEQARYWIF 548
Score = 42.7 bits (96), Expect = 0.001
Identities = 37/182 (20%), Positives = 90/182 (49%), Gaps = 11/182 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++KK + + ++ ++ + ++ + L ++ EE+R L+K+ Q E+ + +
Sbjct: 373 VEKKRREQEEQRQLQQEQLERAKKMEEELELEQQRRTEEIR-LRKQRLQEEQ----QRQE 427
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE-ERSGTAQQKLLEAQQSADE 122
E+ + L K Q A + + RK+++++ ++ E ER+ +Q+ E + +E
Sbjct: 428 EEERKQQLRLKAAQERARQQQ-EEFRRKLRELQRKKQQEEAERAEAEKQRQEELEMQLEE 486
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
+ + + + +R Q + +ARL AE+ K +E +R LA +E+ + A+++
Sbjct: 487 EQKHLMEMAEEERLEYQRRKQEAEE--KARLEAEERRQKEEEAAR-LA-LEEATKQAQEQ 542
Query: 183 VK 184
+
Sbjct: 543 AR 544
>AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein.
Length = 2069
Score = 60.9 bits (141), Expect = 5e-09
Identities = 54/217 (24%), Positives = 106/217 (48%), Gaps = 19/217 (8%)
Query: 7 KMQAMKLEKD--NAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
++ +LE+D +A ++D E + R++ L AE+ + E Q KL + ++ K ++
Sbjct: 565 RLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKATECQHKLLKAKDQ---GKPEV 621
Query: 65 -EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
E A + E+QL K+Q+++E LEK+ + S A + L +Q+ +
Sbjct: 622 GEYAKLEKINAEQQL------------KIQELQEKLEKAVKASTEATELLQNIRQAKERA 669
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
R + L+NR E +L + +E R E+ + + + R+ ++D+++ ++
Sbjct: 670 ERELEKLQNREDSSEGIRKKLV-EAEERRHSLENKVKRLETMERRENRLKDDIQTKSQQI 728
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ KI ELEE+ + S + LEV ++ Q EE
Sbjct: 729 QQMADKILELEEKHREAQVSAQHLEVHLKQKEQHYEE 765
Score = 56.0 bits (129), Expect = 1e-07
Identities = 54/227 (23%), Positives = 102/227 (44%), Gaps = 12/227 (5%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
+++KK+ E ++ DK EQ+ + R +V + + + +L E L +
Sbjct: 446 SMEKKLLIKSKELQDSQDKCHKMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQ 505
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
L + ++ L EV+ + K Q+ D+ + + +++ +AQ +E
Sbjct: 506 DLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQ--VEE 563
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE--LEVAE 180
M LE R D ++L+E+RL AE+ K+ E KL +D+ EV E
Sbjct: 564 MRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKATECQHKLLKAKDQGKPEVGE 623
Query: 181 ----DRVKS-GDAKISELEEEL-KVVGNSLKSLEVSE--EKANQRVE 219
+++ + KI EL+E+L K V S ++ E+ + +A +R E
Sbjct: 624 YAKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAE 670
Score = 54.4 bits (125), Expect = 4e-07
Identities = 52/204 (25%), Positives = 95/204 (46%), Gaps = 23/204 (11%)
Query: 12 KLEKD-NAMDKADTCEQQARDANLRAEKVNEEVRE-------LQKKLAQVEEDLILNKNK 63
KLEK A +A Q R A RAE+ E+++ ++KKL + EE ++
Sbjct: 644 KLEKAVKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEE----RRHS 699
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL----EKSEERSGTAQQKLLEAQQS 119
LE K LE E++ + ++ ++++QQ+ + + EK E +AQ + +Q
Sbjct: 700 LENKVKRLETMERRENRLKDDIQTKSQQIQQMADKILELEEKHREAQVSAQHLEVHLKQK 759
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
KVL+N+ ++D + L N ++ E+A K +S + A +
Sbjct: 760 EQHYEEKIKVLDNQIKKDLADKETLENMMQRHE---EEAHEKGKILSEQKAMI----NAM 812
Query: 180 EDRVKSGDAKISELEEELKVVGNS 203
+ +++S + +I EL E K+ NS
Sbjct: 813 DSKIRSLEQRIVELSEANKLAANS 836
Score = 52.8 bits (121), Expect = 1e-06
Identities = 60/239 (25%), Positives = 106/239 (44%), Gaps = 21/239 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-------VRELQKKLAQV 53
M A ++ + ++ +K +A E Q R + EK++ + + EL+ +L +V
Sbjct: 844 MKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREV 903
Query: 54 ----EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 109
EE + K +L + L+E+E QLTA +A AAL +++Q + +LE++ +
Sbjct: 904 SLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEE 963
Query: 110 QQKLL----EAQQSADENNRMCKV---LENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
Q L E Q+ D C V LE + Q E +L NQ ++A G +
Sbjct: 964 IQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGAN 1023
Query: 163 DEVSRKLAFVED-ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
DE+ + + V+ E+ E ++ K + E LK L+ + E N + E
Sbjct: 1024 DEIVQLRSEVDHLRREITEREMQLTSQK--QTMEALKTTCTMLEEQVMDLEALNDELLE 1080
Score = 45.6 bits (103), Expect = 2e-04
Identities = 57/263 (21%), Positives = 113/263 (42%), Gaps = 23/263 (8%)
Query: 11 MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE--DLILNKNKLEQAN 68
M+ ++ A +K +Q N ++ ++R L++++ ++ E L N + Q N
Sbjct: 788 MQRHEEEAHEKGKILSEQKAMINA----MDSKIRSLEQRIVELSEANKLAANSSLFTQRN 843
Query: 69 KDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+E+ +Q E + L + +++EE LEK + + + +LLE + E
Sbjct: 844 MKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREV 903
Query: 124 NRMCKVLENRAQQDEERMD----QLTNQLKEARLLAEDADGKSDEVSRKLA--FVEDELE 177
+ LE+ Q+ E + QL+ Q +E++L A A + E + A +E+
Sbjct: 904 S-----LEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTA 958
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXX 237
AE+ +++ A E++ + + NS + EE+ NQ E+
Sbjct: 959 EAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDE 1018
Query: 238 XXXXXXKTVKKLQKEVDRLEDEL 260
+ V +L+ EVD L E+
Sbjct: 1019 ASGANDEIV-QLRSEVDHLRREI 1040
Score = 44.4 bits (100), Expect = 5e-04
Identities = 42/190 (22%), Positives = 91/190 (47%), Gaps = 11/190 (5%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV---RELQKKL----AQVEE 55
A+++ ++ KL+ ++ DK + E++ + A + +++ REL+++L A++++
Sbjct: 1144 ALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQ 1203
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE--EDLEKSEERSGTAQQ-K 112
+ L KN + + + L+E + + E + L +++ I+ EK + +QQ K
Sbjct: 1204 QMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTK 1263
Query: 113 LLE-AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
L++ Q D+ + K L +R ++D Q+ Q E +L E + E+ L
Sbjct: 1264 LIDFLQAKMDQPAKKKKGLFSRRKEDPALPTQVPLQYNELKLALEKEKARCAELEEALQK 1323
Query: 172 VEDELEVAED 181
EL A +
Sbjct: 1324 TRIELRSARE 1333
Score = 40.3 bits (90), Expect = 0.007
Identities = 42/207 (20%), Positives = 93/207 (44%), Gaps = 10/207 (4%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D + +++ +L + KA C+ + A + + E +L+K A+ + + +
Sbjct: 583 DLYESELRESRLAAEEFKRKATECQHKLLKAKDQGKPEVGEYAKLEKINAEQQLKIQELQ 642
Query: 62 NKLEQANKDLEEKEKQLT-------ATEAEVAAL-NRK--VQQIEEDLEKSEERSGTAQQ 111
KLE+A K E + L E E+ L NR+ + I + L ++EER + +
Sbjct: 643 EKLEKAVKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEERRHSLEN 702
Query: 112 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
K+ + NR+ ++ ++QQ ++ D++ ++ R A + +K
Sbjct: 703 KVKRLETMERRENRLKDDIQTKSQQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQH 762
Query: 172 VEDELEVAEDRVKSGDAKISELEEELK 198
E++++V ++++K A LE ++
Sbjct: 763 YEEKIKVLDNQIKKDLADKETLENMMQ 789
Score = 36.3 bits (80), Expect = 0.12
Identities = 47/206 (22%), Positives = 99/206 (48%), Gaps = 20/206 (9%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ----ANKDLEEKEKQLTAT 81
+Q ++ L+AE +++++ +L+KK A +E + + KLE + LEE+ K
Sbjct: 1146 QQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQM 1205
Query: 82 EAEVAALNRKVQQIEEDLEKSE----ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQD 137
+ + + R Q ++E L++++ ERS Q LE Q + ++ +E Q
Sbjct: 1206 DLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQ--LENIQVLYSHEKV--KMEGTISQQ 1261
Query: 138 EERMDQLTNQLKEARLLAEDADGKSDE---VSRKLAFVEDELEVAEDRVKSGDAKISELE 194
+ +D L ++ + + + E + ++ +EL++A ++ K A+ +ELE
Sbjct: 1262 TKLIDFLQAKMDQPAKKKKGLFSRRKEDPALPTQVPLQYNELKLALEKEK---ARCAELE 1318
Query: 195 EELKVVGNSLKSLEVSEEKANQRVEE 220
E L+ L+S EE A+++ +
Sbjct: 1319 EALQKTRIELRS--AREEAAHRKATD 1342
Score = 35.5 bits (78), Expect = 0.21
Identities = 39/194 (20%), Positives = 73/194 (37%), Gaps = 4/194 (2%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E Q R A E+ E E + L +++ + L + + + E+QL +
Sbjct: 943 ESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDN 1002
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
A LN + + + L+ E SG A ++++ + D R E + ++ M+ L
Sbjct: 1003 AELNNQNFYLSKQLD---EASG-ANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALK 1058
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
D + +DE+ K E V D + ++ EL+ L S
Sbjct: 1059 TTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRA 1118
Query: 206 SLEVSEEKANQRVE 219
+ ++ Q VE
Sbjct: 1119 RADQRITESRQVVE 1132
>AB095932-1|BAC23108.1| 555|Homo sapiens KIAA2012 protein protein.
Length = 555
Score = 60.9 bits (141), Expect = 5e-09
Identities = 54/186 (29%), Positives = 92/186 (49%), Gaps = 14/186 (7%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+++A LRAE+ E++KK + EE L + +LE+A K EE E + E+
Sbjct: 355 QEKASWDRLRAERAEMRWLEVEKKRREQEEQRQLQQEQLERAKKMEEELELEQQRRTEEI 414
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLE--AQQSADENNRMCKVLENRAQQDE----- 138
+++Q+ E+ ++ EER + K + A+Q +E R + L+ + QQ+E
Sbjct: 415 RLRKQRLQE-EQQRQEEEERKQQLRLKAAQERARQQQEEFRRKLRELQRKKQQEEAERAE 473
Query: 139 ---ERMDQLTNQL-KEARLLAEDADGKSDEVSRKLAFVEDE--LEVAEDRVKSGDAKISE 192
+R ++L QL +E + L E A+ + E R+ E++ LE E R K +A
Sbjct: 474 AEKQRQEELEMQLEEEQKHLMEMAEEERLEYQRRKQEAEEKARLEAEERRQKEEEAARLA 533
Query: 193 LEEELK 198
LEE K
Sbjct: 534 LEEATK 539
Score = 44.0 bits (99), Expect = 6e-04
Identities = 44/178 (24%), Positives = 84/178 (47%), Gaps = 23/178 (12%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN---------EEVRELQKKLAQVEE 55
++++Q +LE+ M++ EQQ R +R K EE R+ Q +L +E
Sbjct: 385 QRQLQQEQLERAKKMEEELELEQQRRTEEIRLRKQRLQEEQQRQEEEERKQQLRLKAAQE 444
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER-SGTAQQKLL 114
+ + + ++L+ K++Q A AE A ++ +++E LE+ ++ A+++ L
Sbjct: 445 RARQQQEEFRRKLRELQRKKQQEEAERAE--AEKQRQEELEMQLEEEQKHLMEMAEEERL 502
Query: 115 EAQQSADENNRMCKV-LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
E Q+ E ++ E R Q++EE ARL E+A ++ E +R F
Sbjct: 503 EYQRRKQEAEEKARLEAEERRQKEEEA----------ARLALEEATKQAQEQARYWIF 550
Score = 42.7 bits (96), Expect = 0.001
Identities = 37/182 (20%), Positives = 90/182 (49%), Gaps = 11/182 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++KK + + ++ ++ + ++ + L ++ EE+R L+K+ Q E+ + +
Sbjct: 375 VEKKRREQEEQRQLQQEQLERAKKMEEELELEQQRRTEEIR-LRKQRLQEEQ----QRQE 429
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE-ERSGTAQQKLLEAQQSADE 122
E+ + L K Q A + + RK+++++ ++ E ER+ +Q+ E + +E
Sbjct: 430 EEERKQQLRLKAAQERARQQQ-EEFRRKLRELQRKKQQEEAERAEAEKQRQEELEMQLEE 488
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
+ + + + +R Q + +ARL AE+ K +E +R LA +E+ + A+++
Sbjct: 489 EQKHLMEMAEEERLEYQRRKQEAEE--KARLEAEERRQKEEEAAR-LA-LEEATKQAQEQ 544
Query: 183 VK 184
+
Sbjct: 545 AR 546
>AB053469-1|BAC54108.1| 720|Homo sapiens ELKS gamma protein.
Length = 720
Score = 60.9 bits (141), Expect = 5e-09
Identities = 46/206 (22%), Positives = 94/206 (45%), Gaps = 5/206 (2%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++K+ ++ + +N ++ E+Q R + + + L +EE L
Sbjct: 266 LDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEK 325
Query: 61 KNKL----EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+ + EQ ++D EK++++ + ++ L KV ++ DL + E ++
Sbjct: 326 ERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSL 385
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
S + + K LE +Q +E ++ +QLK+A A +A S E+S ++ +E E+
Sbjct: 386 ASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARA-SPEMSDRIQHLEREI 444
Query: 177 EVAEDRVKSGDAKISELEEELKVVGN 202
+D A++ L E LK V N
Sbjct: 445 TRYKDESSKAQAEVDRLLEILKEVEN 470
Score = 50.4 bits (115), Expect = 7e-06
Identities = 58/280 (20%), Positives = 119/280 (42%), Gaps = 21/280 (7%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
+ ++ A++L + + +Q +D E+ +L+ L E + + + K+
Sbjct: 221 ENQVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKI 280
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
E + L +KEKQ+ ++L +V+ ++ D ++ T ++ L E +++ +
Sbjct: 281 ENLQEQLRDKEKQM-------SSLKERVKSLQADTTNTDTALTTLEEALAEKERTIE--- 330
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
++ E R + + E+ +++ N K+ + L E ++S K A + D E A
Sbjct: 331 ---RLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLAS 387
Query: 185 SG---DAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXX 241
SG D+++ LE L+ +E +KA++ E
Sbjct: 388 SGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRY 447
Query: 242 XXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
++ K Q EVDRL L I K+ ++ ++ D AEL
Sbjct: 448 KDES-SKAQAEVDRL---LEILKE-VENEKNDKDKKIAEL 482
Score = 45.6 bits (103), Expect = 2e-04
Identities = 51/213 (23%), Positives = 97/213 (45%), Gaps = 17/213 (7%)
Query: 13 LEKDNAMDKADTCEQQARDANLRA--EKVNEEVRELQKKLAQVEE---DLILNKNKLEQA 67
LE++ K ++ + QA L ++V E + KK+A++E + ++NK
Sbjct: 440 LEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVAN 499
Query: 68 NKDLEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
K E+ EK+ +A E A LN QQ+++ L K ++R ++ L E+ Q E
Sbjct: 500 LKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAE 559
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
+ E+ E+++++L +++ + E K + LA E E + R
Sbjct: 560 REMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLA--EKETHLTNLR 617
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
+ + LEE L++ +L + +SE+ AN
Sbjct: 618 AE----RRKHLEEVLEMKQEALLAA-ISEKDAN 645
Score = 45.2 bits (102), Expect = 3e-04
Identities = 42/214 (19%), Positives = 107/214 (50%), Gaps = 17/214 (7%)
Query: 13 LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 72
L+KD+ + + +Q ++ L+ E ++ E + A+ ++ ++++ +++
Sbjct: 390 LKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALE-ARASPEM---SDRIQHLEREIT 445
Query: 73 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 132
+ + + +AEV L ++++E EK+++ A+ + L ++Q D+N ++ L++
Sbjct: 446 RYKDESSKAQAEVDRLLEILKEVEN--EKNDKDKKIAELESLTSRQVKDQNKKVAN-LKH 502
Query: 133 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 192
+ Q ++++ Q+ L+EAR ++ + S ++ L +D +E E+ ++ +E
Sbjct: 503 KEQVEKKKSAQM---LEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAE 559
Query: 193 ----LEEELKVVGNSLKSLE---VSEEKANQRVE 219
L +E N+ K +E ++ EK Q +E
Sbjct: 560 REMVLAQEESARTNAEKQVEELLMAMEKVKQELE 593
Score = 41.1 bits (92), Expect = 0.004
Identities = 44/232 (18%), Positives = 97/232 (41%), Gaps = 14/232 (6%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADT--CEQQARDANLRAEKVNE-EVRELQKKLAQVEEDLI 58
D ++K ++ + + ++M+ T + ++ LR ++ ++ + + Q ++ Q E +
Sbjct: 166 DLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQVD 225
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
+ +LE+ L +K KQ+ E ++ +++ L+ E + Q+K+ Q+
Sbjct: 226 ALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQE 285
Query: 119 SADENNRMCKVLENRA---QQDEERMDQLTNQLKEA--------RLLAEDADGKSDEVSR 167
+ + L+ R Q D D L+EA L E D E
Sbjct: 286 QLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQE 345
Query: 168 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
++ + +L+ +++V +SE E L + SL S K + R++
Sbjct: 346 EIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLK 397
Score = 38.7 bits (86), Expect = 0.023
Identities = 31/170 (18%), Positives = 77/170 (45%), Gaps = 3/170 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q +A R + +N+ ++LQ L + ++ + + L ++ + E+E L E+
Sbjct: 513 QMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESART 572
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
++V+++ +EK ++ + + KL QQS E L ++ E + ++
Sbjct: 573 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQ 632
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 196
+ A + +DA+ E+S ++E+ + + D + +L+++
Sbjct: 633 EALLAAISEKDANIALLELSSSKKKTQEEVAALK---REKDRLVQQLKQQ 679
Score = 37.1 bits (82), Expect = 0.070
Identities = 44/223 (19%), Positives = 110/223 (49%), Gaps = 23/223 (10%)
Query: 4 IKKKMQAMKLEKDNAMDKADTC-EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
I K+++ K +KD + + ++ +Q +D N + + + + +KK AQ+ E+ ++
Sbjct: 464 ILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRRED 523
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
L +++ L++ ++ + +++++EE L +S + TA+++++ AQ+ +
Sbjct: 524 NLNDSSQQLQDSLRKK----------DDRIEELEEALRESVQI--TAEREMVLAQEESAR 571
Query: 123 NNRMCKVLE-----NRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
N +V E + +Q+ E M + +++ LAE ++ + + +E+ LE
Sbjct: 572 TNAEKQVEELLMAMEKVKQELESMKAKLSSTQQS--LAEKETHLTNLRAERRKHLEEVLE 629
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ ++ + A ISE + + ++ S + EE A + E+
Sbjct: 630 MKQEALL---AAISEKDANIALLELSSSKKKTQEEVAALKREK 669
Score = 37.1 bits (82), Expect = 0.070
Identities = 25/107 (23%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 2 DAIKKKMQAMKLEK-----DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 56
+ ++KK A LE+ DN D + + R + R E++ E +RE + A+ E
Sbjct: 504 EQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMV 563
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 103
L ++ A K +EE + + E+ ++ K+ ++ L + E
Sbjct: 564 LAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKE 610
Score = 36.7 bits (81), Expect = 0.092
Identities = 24/104 (23%), Positives = 56/104 (53%), Gaps = 7/104 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M+ +K+++++MK + + + E++ NLRAE+ R+ +++ +++++ +L
Sbjct: 585 MEKVKQELESMKAKLSST--QQSLAEKETHLTNLRAER-----RKHLEEVLEMKQEALLA 637
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 104
+ AN L E T+ EVAAL R+ ++ + L++ +
Sbjct: 638 AISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQ 681
>AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein.
Length = 992
Score = 60.9 bits (141), Expect = 5e-09
Identities = 46/206 (22%), Positives = 94/206 (45%), Gaps = 5/206 (2%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++K+ ++ + +N ++ E+Q R + + + L +EE L
Sbjct: 538 LDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEK 597
Query: 61 KNKL----EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+ + EQ ++D EK++++ + ++ L KV ++ DL + E ++
Sbjct: 598 ERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSL 657
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
S + + K LE +Q +E ++ +QLK+A A +A S E+S ++ +E E+
Sbjct: 658 ASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARA-SPEMSDRIQHLEREI 716
Query: 177 EVAEDRVKSGDAKISELEEELKVVGN 202
+D A++ L E LK V N
Sbjct: 717 TRYKDESSKAQAEVDRLLEILKEVEN 742
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/254 (16%), Positives = 110/254 (43%), Gaps = 7/254 (2%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
E + ++ +++ L +EE++ + K+ + ++ EE+ KQ+ + + K+ Q++
Sbjct: 385 EMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVK 444
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
++L + + Q KL ++ + +VL+ E+R L ++ RL E
Sbjct: 445 QELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE 504
Query: 157 DADGKSDEVSRKLAFVED-------ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 209
+ + ++ ++++ + + E+ +D + + K++ L+++++ + L+ E
Sbjct: 505 EKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEK 564
Query: 210 SEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKS 269
+RV+ +T+++L+++ DR E E D YK
Sbjct: 565 QMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKK 624
Query: 270 LADEMDSTFAELAG 283
++ + L G
Sbjct: 625 DLKDLKEKVSLLQG 638
Score = 45.6 bits (103), Expect = 2e-04
Identities = 44/227 (19%), Positives = 91/227 (40%), Gaps = 11/227 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K+++ E K +T Q D+ E + E + +++ A ++ ++ + +
Sbjct: 443 VKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLR 502
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
LE+ L +K KQ+ E ++ +++ L+ E + Q+K+ Q+ +
Sbjct: 503 LEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDK 562
Query: 124 NRMCKVLENRA---QQDEERMDQLTNQLKEA--------RLLAEDADGKSDEVSRKLAFV 172
+ L+ R Q D D L+EA L E D E ++
Sbjct: 563 EKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNY 622
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ +L+ +++V +SE E L + SL S K + R++
Sbjct: 623 KKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLK 669
Score = 45.6 bits (103), Expect = 2e-04
Identities = 51/213 (23%), Positives = 97/213 (45%), Gaps = 17/213 (7%)
Query: 13 LEKDNAMDKADTCEQQARDANLRA--EKVNEEVRELQKKLAQVEE---DLILNKNKLEQA 67
LE++ K ++ + QA L ++V E + KK+A++E + ++NK
Sbjct: 712 LEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVAN 771
Query: 68 NKDLEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
K E+ EK+ +A E A LN QQ+++ L K ++R ++ L E+ Q E
Sbjct: 772 LKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAE 831
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
+ E+ E+++++L +++ + E K + LA E E + R
Sbjct: 832 REMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLA--EKETHLTNLR 889
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
+ + LEE L++ +L + +SE+ AN
Sbjct: 890 AE----RRKHLEEVLEMKQEALLAA-ISEKDAN 917
Score = 45.2 bits (102), Expect = 3e-04
Identities = 42/214 (19%), Positives = 107/214 (50%), Gaps = 17/214 (7%)
Query: 13 LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 72
L+KD+ + + +Q ++ L+ E ++ E + A+ ++ ++++ +++
Sbjct: 662 LKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALE-ARASPEM---SDRIQHLEREIT 717
Query: 73 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 132
+ + + +AEV L ++++E EK+++ A+ + L ++Q D+N ++ L++
Sbjct: 718 RYKDESSKAQAEVDRLLEILKEVEN--EKNDKDKKIAELESLTSRQVKDQNKKVAN-LKH 774
Query: 133 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 192
+ Q ++++ Q+ L+EAR ++ + S ++ L +D +E E+ ++ +E
Sbjct: 775 KEQVEKKKSAQM---LEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAE 831
Query: 193 ----LEEELKVVGNSLKSLE---VSEEKANQRVE 219
L +E N+ K +E ++ EK Q +E
Sbjct: 832 REMVLAQEESARTNAEKQVEELLMAMEKVKQELE 865
Score = 38.7 bits (86), Expect = 0.023
Identities = 31/170 (18%), Positives = 77/170 (45%), Gaps = 3/170 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q +A R + +N+ ++LQ L + ++ + + L ++ + E+E L E+
Sbjct: 785 QMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESART 844
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
++V+++ +EK ++ + + KL QQS E L ++ E + ++
Sbjct: 845 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQ 904
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 196
+ A + +DA+ E+S ++E+ + + D + +L+++
Sbjct: 905 EALLAAISEKDANIALLELSSSKKKTQEEVAALK---REKDRLVQQLKQQ 951
Score = 37.1 bits (82), Expect = 0.070
Identities = 44/185 (23%), Positives = 86/185 (46%), Gaps = 23/185 (12%)
Query: 36 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI 95
AE E + L + + ++L L + K LEE E ++ E + LN + + I
Sbjct: 260 AELTEENFQRLHAEHERQAKELFLLR-------KTLEEMELRI---ETQKQTLNARDESI 309
Query: 96 EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL-KEARLL 154
++ LE Q K L A+ + +++ R ++ E A+ ++ L Q KE +L
Sbjct: 310 KKLLE-------MLQSKGLSAKATEEDHERTRRLAE--AEMHVHHLESLLEQKEKENSML 360
Query: 155 AEDADGKSDEV--SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV-GNSLKSLEVSE 211
E+ + + S K ++ +E+ + ++ S + + +LEEE++++ N S E E
Sbjct: 361 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE 420
Query: 212 EKANQ 216
E+ Q
Sbjct: 421 EEMKQ 425
Score = 37.1 bits (82), Expect = 0.070
Identities = 44/223 (19%), Positives = 110/223 (49%), Gaps = 23/223 (10%)
Query: 4 IKKKMQAMKLEKDNAMDKADTC-EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
I K+++ K +KD + + ++ +Q +D N + + + + +KK AQ+ E+ ++
Sbjct: 736 ILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRRED 795
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
L +++ L++ ++ + +++++EE L +S + TA+++++ AQ+ +
Sbjct: 796 NLNDSSQQLQDSLRKK----------DDRIEELEEALRESVQI--TAEREMVLAQEESAR 843
Query: 123 NNRMCKVLE-----NRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
N +V E + +Q+ E M + +++ LAE ++ + + +E+ LE
Sbjct: 844 TNAEKQVEELLMAMEKVKQELESMKAKLSSTQQS--LAEKETHLTNLRAERRKHLEEVLE 901
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ ++ + A ISE + + ++ S + EE A + E+
Sbjct: 902 MKQEALL---AAISEKDANIALLELSSSKKKTQEEVAALKREK 941
Score = 37.1 bits (82), Expect = 0.070
Identities = 25/107 (23%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 2 DAIKKKMQAMKLEK-----DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 56
+ ++KK A LE+ DN D + + R + R E++ E +RE + A+ E
Sbjct: 776 EQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMV 835
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 103
L ++ A K +EE + + E+ ++ K+ ++ L + E
Sbjct: 836 LAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKE 882
Score = 36.7 bits (81), Expect = 0.092
Identities = 24/104 (23%), Positives = 56/104 (53%), Gaps = 7/104 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M+ +K+++++MK + + + E++ NLRAE+ R+ +++ +++++ +L
Sbjct: 857 MEKVKQELESMKAKLSST--QQSLAEKETHLTNLRAER-----RKHLEEVLEMKQEALLA 909
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 104
+ AN L E T+ EVAAL R+ ++ + L++ +
Sbjct: 910 AISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQ 953
>AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein.
Length = 1003
Score = 60.9 bits (141), Expect = 5e-09
Identities = 46/206 (22%), Positives = 94/206 (45%), Gaps = 5/206 (2%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++K+ ++ + +N ++ E+Q R + + + L +EE L
Sbjct: 549 LDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEK 608
Query: 61 KNKL----EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+ + EQ ++D EK++++ + ++ L KV ++ DL + E ++
Sbjct: 609 ERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSL 668
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
S + + K LE +Q +E ++ +QLK+A A +A S E+S ++ +E E+
Sbjct: 669 ASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARA-SPEMSDRIQHLEREI 727
Query: 177 EVAEDRVKSGDAKISELEEELKVVGN 202
+D A++ L E LK V N
Sbjct: 728 TRYKDESSKAQAEVDRLLEILKEVEN 753
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/254 (16%), Positives = 110/254 (43%), Gaps = 7/254 (2%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
E + ++ +++ L +EE++ + K+ + ++ EE+ KQ+ + + K+ Q++
Sbjct: 396 EMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVK 455
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
++L + + Q KL ++ + +VL+ E+R L ++ RL E
Sbjct: 456 QELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE 515
Query: 157 DADGKSDEVSRKLAFVED-------ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 209
+ + ++ ++++ + + E+ +D + + K++ L+++++ + L+ E
Sbjct: 516 EKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEK 575
Query: 210 SEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKS 269
+RV+ +T+++L+++ DR E E D YK
Sbjct: 576 QMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKK 635
Query: 270 LADEMDSTFAELAG 283
++ + L G
Sbjct: 636 DLKDLKEKVSLLQG 649
Score = 45.6 bits (103), Expect = 2e-04
Identities = 44/227 (19%), Positives = 91/227 (40%), Gaps = 11/227 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K+++ E K +T Q D+ E + E + +++ A ++ ++ + +
Sbjct: 454 VKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLR 513
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
LE+ L +K KQ+ E ++ +++ L+ E + Q+K+ Q+ +
Sbjct: 514 LEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDK 573
Query: 124 NRMCKVLENRA---QQDEERMDQLTNQLKEA--------RLLAEDADGKSDEVSRKLAFV 172
+ L+ R Q D D L+EA L E D E ++
Sbjct: 574 EKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNY 633
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ +L+ +++V +SE E L + SL S K + R++
Sbjct: 634 KKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLK 680
Score = 45.6 bits (103), Expect = 2e-04
Identities = 51/213 (23%), Positives = 97/213 (45%), Gaps = 17/213 (7%)
Query: 13 LEKDNAMDKADTCEQQARDANLRA--EKVNEEVRELQKKLAQVEE---DLILNKNKLEQA 67
LE++ K ++ + QA L ++V E + KK+A++E + ++NK
Sbjct: 723 LEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVAN 782
Query: 68 NKDLEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
K E+ EK+ +A E A LN QQ+++ L K ++R ++ L E+ Q E
Sbjct: 783 LKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAE 842
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
+ E+ E+++++L +++ + E K + LA E E + R
Sbjct: 843 REMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLA--EKETHLTNLR 900
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
+ + LEE L++ +L + +SE+ AN
Sbjct: 901 AE----RRKHLEEVLEMKQEALLAA-ISEKDAN 928
Score = 45.2 bits (102), Expect = 3e-04
Identities = 42/214 (19%), Positives = 107/214 (50%), Gaps = 17/214 (7%)
Query: 13 LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 72
L+KD+ + + +Q ++ L+ E ++ E + A+ ++ ++++ +++
Sbjct: 673 LKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALE-ARASPEM---SDRIQHLEREIT 728
Query: 73 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 132
+ + + +AEV L ++++E EK+++ A+ + L ++Q D+N ++ L++
Sbjct: 729 RYKDESSKAQAEVDRLLEILKEVEN--EKNDKDKKIAELESLTSRQVKDQNKKVAN-LKH 785
Query: 133 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 192
+ Q ++++ Q+ L+EAR ++ + S ++ L +D +E E+ ++ +E
Sbjct: 786 KEQVEKKKSAQM---LEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAE 842
Query: 193 ----LEEELKVVGNSLKSLE---VSEEKANQRVE 219
L +E N+ K +E ++ EK Q +E
Sbjct: 843 REMVLAQEESARTNAEKQVEELLMAMEKVKQELE 876
Score = 38.7 bits (86), Expect = 0.023
Identities = 31/170 (18%), Positives = 77/170 (45%), Gaps = 3/170 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q +A R + +N+ ++LQ L + ++ + + L ++ + E+E L E+
Sbjct: 796 QMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESART 855
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
++V+++ +EK ++ + + KL QQS E L ++ E + ++
Sbjct: 856 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQ 915
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 196
+ A + +DA+ E+S ++E+ + + D + +L+++
Sbjct: 916 EALLAAISEKDANIALLELSSSKKKTQEEVAALK---REKDRLVQQLKQQ 962
Score = 37.1 bits (82), Expect = 0.070
Identities = 44/185 (23%), Positives = 86/185 (46%), Gaps = 23/185 (12%)
Query: 36 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI 95
AE E + L + + ++L L + K LEE E ++ E + LN + + I
Sbjct: 271 AELTEENFQRLHAEHERQAKELFLLR-------KTLEEMELRI---ETQKQTLNARDESI 320
Query: 96 EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL-KEARLL 154
++ LE Q K L A+ + +++ R ++ E A+ ++ L Q KE +L
Sbjct: 321 KKLLE-------MLQSKGLSAKATEEDHERTRRLAE--AEMHVHHLESLLEQKEKENSML 371
Query: 155 AEDADGKSDEV--SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV-GNSLKSLEVSE 211
E+ + + S K ++ +E+ + ++ S + + +LEEE++++ N S E E
Sbjct: 372 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE 431
Query: 212 EKANQ 216
E+ Q
Sbjct: 432 EEMKQ 436
Score = 37.1 bits (82), Expect = 0.070
Identities = 44/223 (19%), Positives = 110/223 (49%), Gaps = 23/223 (10%)
Query: 4 IKKKMQAMKLEKDNAMDKADTC-EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
I K+++ K +KD + + ++ +Q +D N + + + + +KK AQ+ E+ ++
Sbjct: 747 ILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRRED 806
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
L +++ L++ ++ + +++++EE L +S + TA+++++ AQ+ +
Sbjct: 807 NLNDSSQQLQDSLRKK----------DDRIEELEEALRESVQI--TAEREMVLAQEESAR 854
Query: 123 NNRMCKVLE-----NRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
N +V E + +Q+ E M + +++ LAE ++ + + +E+ LE
Sbjct: 855 TNAEKQVEELLMAMEKVKQELESMKAKLSSTQQS--LAEKETHLTNLRAERRKHLEEVLE 912
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ ++ + A ISE + + ++ S + EE A + E+
Sbjct: 913 MKQEALL---AAISEKDANIALLELSSSKKKTQEEVAALKREK 952
Score = 37.1 bits (82), Expect = 0.070
Identities = 25/107 (23%), Positives = 49/107 (45%), Gaps = 5/107 (4%)
Query: 2 DAIKKKMQAMKLEK-----DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 56
+ ++KK A LE+ DN D + + R + R E++ E +RE + A+ E
Sbjct: 787 EQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMV 846
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 103
L ++ A K +EE + + E+ ++ K+ ++ L + E
Sbjct: 847 LAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKE 893
Score = 36.7 bits (81), Expect = 0.092
Identities = 24/104 (23%), Positives = 56/104 (53%), Gaps = 7/104 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M+ +K+++++MK + + + E++ NLRAE+ R+ +++ +++++ +L
Sbjct: 868 MEKVKQELESMKAKLSST--QQSLAEKETHLTNLRAER-----RKHLEEVLEMKQEALLA 920
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 104
+ AN L E T+ EVAAL R+ ++ + L++ +
Sbjct: 921 AISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQ 964
>AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein.
Length = 948
Score = 60.9 bits (141), Expect = 5e-09
Identities = 46/206 (22%), Positives = 94/206 (45%), Gaps = 5/206 (2%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++K+ ++ + +N ++ E+Q R + + + L +EE L
Sbjct: 538 LDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEK 597
Query: 61 KNKL----EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+ + EQ ++D EK++++ + ++ L KV ++ DL + E ++
Sbjct: 598 ERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSL 657
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
S + + K LE +Q +E ++ +QLK+A A +A S E+S ++ +E E+
Sbjct: 658 ASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARA-SPEMSDRIQHLEREI 716
Query: 177 EVAEDRVKSGDAKISELEEELKVVGN 202
+D A++ L E LK V N
Sbjct: 717 TRYKDESSKAQAEVDRLLEILKEVEN 742
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/254 (16%), Positives = 110/254 (43%), Gaps = 7/254 (2%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
E + ++ +++ L +EE++ + K+ + ++ EE+ KQ+ + + K+ Q++
Sbjct: 385 EMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVK 444
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
++L + + Q KL ++ + +VL+ E+R L ++ RL E
Sbjct: 445 QELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE 504
Query: 157 DADGKSDEVSRKLAFVED-------ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 209
+ + ++ ++++ + + E+ +D + + K++ L+++++ + L+ E
Sbjct: 505 EKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEK 564
Query: 210 SEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKS 269
+RV+ +T+++L+++ DR E E D YK
Sbjct: 565 QMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKK 624
Query: 270 LADEMDSTFAELAG 283
++ + L G
Sbjct: 625 DLKDLKEKVSLLQG 638
Score = 45.6 bits (103), Expect = 2e-04
Identities = 44/227 (19%), Positives = 91/227 (40%), Gaps = 11/227 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K+++ E K +T Q D+ E + E + +++ A ++ ++ + +
Sbjct: 443 VKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLR 502
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
LE+ L +K KQ+ E ++ +++ L+ E + Q+K+ Q+ +
Sbjct: 503 LEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDK 562
Query: 124 NRMCKVLENRA---QQDEERMDQLTNQLKEA--------RLLAEDADGKSDEVSRKLAFV 172
+ L+ R Q D D L+EA L E D E ++
Sbjct: 563 EKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNY 622
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ +L+ +++V +SE E L + SL S K + R++
Sbjct: 623 KKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLK 669
Score = 37.1 bits (82), Expect = 0.070
Identities = 44/185 (23%), Positives = 86/185 (46%), Gaps = 23/185 (12%)
Query: 36 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI 95
AE E + L + + ++L L + K LEE E ++ E + LN + + I
Sbjct: 260 AELTEENFQRLHAEHERQAKELFLLR-------KTLEEMELRI---ETQKQTLNARDESI 309
Query: 96 EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL-KEARLL 154
++ LE Q K L A+ + +++ R ++ E A+ ++ L Q KE +L
Sbjct: 310 KKLLE-------MLQSKGLSAKATEEDHERTRRLAE--AEMHVHHLESLLEQKEKENSML 360
Query: 155 AEDADGKSDEV--SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV-GNSLKSLEVSE 211
E+ + + S K ++ +E+ + ++ S + + +LEEE++++ N S E E
Sbjct: 361 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE 420
Query: 212 EKANQ 216
E+ Q
Sbjct: 421 EEMKQ 425
Score = 36.7 bits (81), Expect = 0.092
Identities = 24/104 (23%), Positives = 56/104 (53%), Gaps = 7/104 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M+ +K+++++MK + + + E++ NLRAE+ R+ +++ +++++ +L
Sbjct: 813 MEKVKQELESMKAKLSST--QQSLAEKETHLTNLRAER-----RKHLEEVLEMKQEALLA 865
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 104
+ AN L E T+ EVAAL R+ ++ + L++ +
Sbjct: 866 AISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQ 909
Score = 35.5 bits (78), Expect = 0.21
Identities = 44/222 (19%), Positives = 107/222 (48%), Gaps = 29/222 (13%)
Query: 13 LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 72
L+KD+ + + +Q ++ L+ E ++ E + A+ ++ ++++ +++
Sbjct: 662 LKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALE-ARASPEM---SDRIQHLEREIT 717
Query: 73 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 132
+ + + +AEV L ++++E EK+++ A+ + L ++Q D+N ++ L++
Sbjct: 718 RYKDESSKAQAEVDRLLEILKEVEN--EKNDKDKKIAELESLTSRQVKDQNKKVAN-LKH 774
Query: 133 RAQQDEERMDQLTNQLKEARLLAEDADGKS-----DEVSRKLAFVEDELEVAEDRVKSGD 187
+ Q ++++ Q+ L+EAR ++ + S +E+ + V+ ELE + ++ S
Sbjct: 775 KEQVEKKKSAQM---LEEARRREDNLNDSSQQLQVEELLMAMEKVKQELESMKAKLSSTQ 831
Query: 188 AKISELEEEL-KVVGNSLKSLE-------------VSEEKAN 215
++E E L + K LE +SE+ AN
Sbjct: 832 QSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDAN 873
Score = 32.7 bits (71), Expect = 1.5
Identities = 20/103 (19%), Positives = 53/103 (51%), Gaps = 3/103 (2%)
Query: 4 IKKKMQAMKLEKDNAMDKADTC-EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
I K+++ K +KD + + ++ +Q +D N + + + + +KK AQ+ E+ ++
Sbjct: 736 ILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRRED 795
Query: 63 KLEQANKDLEEKE--KQLTATEAEVAALNRKVQQIEEDLEKSE 103
L +++ L+ +E + + E+ ++ K+ ++ L + E
Sbjct: 796 NLNDSSQQLQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKE 838
Score = 31.9 bits (69), Expect = 2.6
Identities = 33/196 (16%), Positives = 85/196 (43%), Gaps = 12/196 (6%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKV----NEEVRELQKKLAQVEEDLILN 60
K + + E D ++ E + D + + ++ + +V++ KK+A ++ +
Sbjct: 720 KDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVE 779
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K K Q ++ +E L + ++ +V+++ +EK ++ + + KL QQS
Sbjct: 780 KKKSAQMLEEARRREDNLNDSSQQL-----QVEELLMAMEKVKQELESMKAKLSSTQQSL 834
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
E L ++ E + ++ + A + +DA+ E+S ++E+ +
Sbjct: 835 AEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALK 894
Query: 181 DRVKSGDAKISELEEE 196
+ D + +L+++
Sbjct: 895 ---REKDRLVQQLKQQ 907
>BC127816-1|AAI27817.1| 416|Homo sapiens Unknown (protein for
IMAGE:40131779) protein.
Length = 416
Score = 60.5 bits (140), Expect = 7e-09
Identities = 38/197 (19%), Positives = 101/197 (51%), Gaps = 4/197 (2%)
Query: 4 IKKKMQAMKLEKDNAMD-KADTCEQQARDANLRAEKVNEEVRELQKKL-AQVEEDLILNK 61
+K+K++ KL + +AD ++ + + + + EE EL +L Q EE + +
Sbjct: 205 LKRKLERAKLLLPQQLQAEADHLGKELQSVSAKLQAQVEE-NELWNRLNQQQEEKMWRQE 263
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
K+++ + ++E+E+++ E ++ +Q+ EE + + EE+ Q+K+ ++
Sbjct: 264 EKIQEWEEKIQEQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM-QEQEKMRRQEEKIR 322
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E + + + ++ EE++ + +++E + ++ + K E K+ E++++ E+
Sbjct: 323 EQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 382
Query: 182 RVKSGDAKISELEEELK 198
+++ + K+ E E L+
Sbjct: 383 KMRRQEEKMWEQEVRLR 399
Score = 55.6 bits (128), Expect = 2e-07
Identities = 36/197 (18%), Positives = 98/197 (49%), Gaps = 8/197 (4%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D + K++Q++ + +++ + + + + + E+++E ++K+ + EE + +
Sbjct: 225 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 284
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
K+ + + ++E+E+++ E ++ K+++ EE + + EE+ ++K+ E ++
Sbjct: 285 EKIREQEEMMQEQEEKMGEQEEKMQE-QEKMRRQEEKIREQEEKIREQKEKIREQEEKIW 343
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E + E Q+ EE+M + ++ E + K E K+ E+++ E
Sbjct: 344 EQEEKIREQEEMMQEQEEKMWEQEEKMCE-------QEEKMQEQEEKMRRQEEKMWEQEV 396
Query: 182 RVKSGDAKISELEEELK 198
R++ + K+ E +E L+
Sbjct: 397 RLRQQEEKMQEHQEHLE 413
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/154 (17%), Positives = 77/154 (50%), Gaps = 1/154 (0%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E++ ++ + ++ E++RE ++K+ + EE + + K+ + + ++E+EK + E ++
Sbjct: 263 EEKIQEWEEKIQEQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK-MRRQEEKI 321
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
K+++ +E + + EE+ ++K+ E ++ E E + + EE+M +
Sbjct: 322 REQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 381
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+++ + + + + K+ ++ LE A
Sbjct: 382 EKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 415
Score = 49.6 bits (113), Expect = 1e-05
Identities = 28/150 (18%), Positives = 74/150 (49%), Gaps = 5/150 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+ I+++ + ++ +++ ++ + ++Q + EK+ E Q+K+ + EE + +
Sbjct: 271 EKIQEQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE-----QEKMRRQEEKIREQE 325
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
K+ + + + E+E+++ E ++ +Q+ EE + + EE+ ++K+ E ++
Sbjct: 326 EKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 385
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEA 151
E R +Q EE+M + L+ A
Sbjct: 386 RQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 415
Score = 42.7 bits (96), Expect = 0.001
Identities = 41/202 (20%), Positives = 90/202 (44%), Gaps = 9/202 (4%)
Query: 22 ADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT 81
A EQ + +K + + EL K+ + +L N E+ + + +++L
Sbjct: 132 AGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLV 191
Query: 82 EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
E+E + + V++++ LE++ + QQ EA E + L+ AQ +E +
Sbjct: 192 ESEKSEIQLNVKELKRKLERA--KLLLPQQLQAEADHLGKELQSVSAKLQ--AQVEENEL 247
Query: 142 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 201
NQ +E ++ ++ K E K+ E+++ E++++ + + E EE++
Sbjct: 248 WNRLNQQQEEKMWRQEE--KIQEWEEKIQEQEEKIREQEEKIREQEEMMQEQEEKMGEQE 305
Query: 202 NSLKSLEV---SEEKANQRVEE 220
++ E EEK ++ E+
Sbjct: 306 EKMQEQEKMRRQEEKIREQEEK 327
>AK092490-1|BAC03904.1| 280|Homo sapiens protein ( Homo sapiens
cDNA FLJ35171 fis, clone PLACE6013220, weakly similar to
TRICHOHYALIN. ).
Length = 280
Score = 60.5 bits (140), Expect = 7e-09
Identities = 42/188 (22%), Positives = 92/188 (48%), Gaps = 1/188 (0%)
Query: 33 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 92
+L + E +RE +++L + EE +++L + + L E+E++L E + ++
Sbjct: 3 SLLNRRQEERLREQEERLREQEERQREQEDRLHEQEERLREQEERLCEQEERLCEQEERL 62
Query: 93 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
++ EE L + EER +++L E ++ E + E R + EER+ + +L E
Sbjct: 63 REHEERLCEQEERLCEQEERLREQEERLHEQEERLREQEERLCEQEERLREHEERLCEQE 122
Query: 153 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
+ + + E +L E+ L E+R++ + ++ E +E+L L+ +E E
Sbjct: 123 ERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCE-QEKLPGQERLLEEVEKLLE 181
Query: 213 KANQRVEE 220
+ ++ E+
Sbjct: 182 QERRQEEQ 189
Score = 57.6 bits (133), Expect = 5e-08
Identities = 43/188 (22%), Positives = 90/188 (47%), Gaps = 4/188 (2%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E++ R+ R + + + E +++L + EE L + +L + + L E E++L E +
Sbjct: 17 EERLREQEERQREQEDRLHEQEERLREQEERLCEQEERLCEQEERLREHEERLCEQEERL 76
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN-RMCKVLENRAQQDEERMDQL 144
++++ EE L + EER +++L E ++ E+ R+C+ E R ++ EER+ +
Sbjct: 77 CEQEERLREQEERLHEQEERLREQEERLCEQEERLREHEERLCEQ-EERLREQEERLCEQ 135
Query: 145 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL 204
+L+E + + + E +L E E ++R+ K+ E E + L
Sbjct: 136 EERLREQEERLCEQEERLREQEERLC--EQEKLPGQERLLEEVEKLLEQERRQEEQERLL 193
Query: 205 KSLEVSEE 212
+ + EE
Sbjct: 194 ERERLLEE 201
Score = 54.4 bits (125), Expect = 4e-07
Identities = 41/172 (23%), Positives = 78/172 (45%), Gaps = 2/172 (1%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E++ R+ R + E RE + +L + EE L + +L + + L E+E++L E +
Sbjct: 10 EERLREQEERLREQEERQREQEDRLHEQEERLREQEERLCEQEERLCEQEERLREHEERL 69
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
++ + EE L + EER +++L E ++ E + E R + EER+ +
Sbjct: 70 CEQEERLCEQEERLREQEERLHEQEERLREQEERLCEQEERLREHEERLCEQEERLREQE 129
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 197
+L E + + + E +L E E + E G ++ E E+L
Sbjct: 130 ERLCEQEERLREQEERLCEQEERLR--EQEERLCEQEKLPGQERLLEEVEKL 179
Score = 52.4 bits (120), Expect = 2e-06
Identities = 44/194 (22%), Positives = 89/194 (45%), Gaps = 6/194 (3%)
Query: 25 CEQQAR--DANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATE 82
CEQ+ R + R + E + E +++L + EE L + +L + + L E+E++L E
Sbjct: 49 CEQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLREQEERLCEQE 108
Query: 83 AEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 142
+ ++ + EE L + EER +++L E ++ E + E R ++E++
Sbjct: 109 ERLREHEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERL-CEQEKLP 167
Query: 143 QLTNQLKEARLLAEDADGKSDE---VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKV 199
L+E L E + ++ + R+ E E + ++R + ++ E E L+
Sbjct: 168 GQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEKLLEQERQQEEQERLLERERLLEE 227
Query: 200 VGNSLKSLEVSEEK 213
V L+ EE+
Sbjct: 228 VEKLLEQERRQEEQ 241
Score = 52.0 bits (119), Expect = 2e-06
Identities = 40/179 (22%), Positives = 86/179 (48%), Gaps = 3/179 (1%)
Query: 20 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 79
D+ E++ R+ R + E + E +++L + EE L + +L + + L E+E++L
Sbjct: 32 DRLHEQEERLREQEERLCEQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLH 91
Query: 80 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 139
E + ++ + EE L + EER +++L E ++ E + E R + EE
Sbjct: 92 EQEERLREQEERLCEQEERLREHEERLCEQEERLREQEERLCEQEERLREQEERLCEQEE 151
Query: 140 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 198
R+ + +L E L + +EV + L ++ + ++R+ + + E+E+ L+
Sbjct: 152 RLREQEERLCEQEKL-PGQERLLEEVEKLLE--QERRQEEQERLLERERLLEEVEKLLE 207
Score = 43.2 bits (97), Expect = 0.001
Identities = 32/117 (27%), Positives = 63/117 (53%), Gaps = 7/117 (5%)
Query: 25 CEQQARDANLRAEKVNEEVREL-QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 83
CEQ+ E++ EEV +L +++ Q E++ +L + +L + + L E+E+Q E
Sbjct: 161 CEQEKLPGQ---ERLLEEVEKLLEQERRQEEQERLLERERLLEEVEKLLEQERQQEEQE- 216
Query: 84 EVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 140
+ R ++++E+ LE +ER Q++LLE ++ DE + +E +Q+ R
Sbjct: 217 RLLERERLLEEVEKLLE--QERRQEEQERLLERERLLDEVEELLDEVEELLEQERLR 271
>X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy chain
(1085 AA) protein.
Length = 1085
Score = 60.1 bits (139), Expect = 9e-09
Identities = 50/217 (23%), Positives = 110/217 (50%), Gaps = 13/217 (5%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKK++ ++ E ++A A E++A+ A A + EE+++ Q A +E +
Sbjct: 873 KKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 929
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN LEQ KDL E ++ L + ++ L +++++E +LE ++++ + + L +
Sbjct: 930 KN-LEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRK 988
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
++ E + + ++ +D+L ++K + AE+AD +++ K + E
Sbjct: 989 YERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHE 1048
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
LE AE+R ++++++L + + +S + SEE
Sbjct: 1049 LEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESEE 1085
Score = 58.4 bits (135), Expect = 3e-08
Identities = 56/254 (22%), Positives = 114/254 (44%), Gaps = 26/254 (10%)
Query: 11 MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE----Q 66
++ E +N +D + C+Q + A + E +EV E + ++ +L K KLE +
Sbjct: 37 VQAESENLLDAEERCDQLIK-AKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE 95
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
KD+++ E L E E A KV+ + E+L +E KL +++ E ++
Sbjct: 96 LKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIA----KLTREKKALQEAHQ- 150
Query: 127 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
+ L++ Q +E++++ L + ED + ++ E +L V +R K
Sbjct: 151 -QALDD-LQAEEDKVNSLNKTKSKLEQQVEDLESSLEQ--------EKKLRVDLERNK-- 198
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTV 246
+LE +LK+ S+ LE +++ ++R+++ K +
Sbjct: 199 ----RKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKI 254
Query: 247 KKLQKEVDRLEDEL 260
K+LQ ++ LE+E+
Sbjct: 255 KELQARIEELEEEI 268
Score = 55.6 bits (128), Expect = 2e-07
Identities = 49/285 (17%), Positives = 119/285 (41%), Gaps = 1/285 (0%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ ++ + A + A+ E + ++ N + E K L V+ L
Sbjct: 740 VETMQSALDAEVRRANEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDT 799
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ L+ A + E+ ++QL E L +V+++ LE++E A+Q+LL++ +
Sbjct: 800 QLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERV 859
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L + ++ E + QL +++++A A +A+ K+ + A + +EL+ +
Sbjct: 860 QLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQ 919
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + LE+ +K + + L E ++ + +++++
Sbjct: 920 DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKN 979
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K ++ V L + ++ L D +D ++ Y
Sbjct: 980 TESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSY 1024
Score = 53.6 bits (123), Expect = 8e-07
Identities = 45/261 (17%), Positives = 115/261 (44%), Gaps = 8/261 (3%)
Query: 5 KKKMQAMKLEKDNAMDKADT-CEQQARDANLRAEKVNEEVRELQKKLAQVE---EDLILN 60
+ K + +++ +++A Q+ +D+ + E VN + L+K +++ EDL+++
Sbjct: 518 RTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVD 577
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ L++K++ AE K ++ + +LE S + S + +L + + +
Sbjct: 578 VERANSLAAALDKKQRNFDKVLAE---WKTKCEESQAELEASLKESRSLSTELFKLKNAY 634
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+E + ++ + E+ + LT Q+ E + + ++ + A ++ LE AE
Sbjct: 635 EEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAE 694
Query: 181 DRVKSGDAKISELEEELKVVGNSL-KSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
++ +AKI ++ EL V + + + + +E+ Q +
Sbjct: 695 AALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRRA 754
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
+ KK++ +++ +E +L
Sbjct: 755 NEAIRLKKKMEGDLNEIEIQL 775
Score = 52.4 bits (120), Expect = 2e-06
Identities = 47/281 (16%), Positives = 115/281 (40%), Gaps = 8/281 (2%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D + M+++ K N T E Q +A + E++ + EL + ++++ +
Sbjct: 374 IDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEA--- 430
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ ++ LEEKE ++ A ++ ++++ LE+ + L ++
Sbjct: 431 ----GELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALGHALQSSRHDC 486
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE-DADGKSDEVSRKLAFVEDELEVA 179
D + + + + + + +++ + R E DA +++E+ + L+ +
Sbjct: 487 DLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDS 546
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
E++V++ +AK + LE+ + + ++ L V E+AN
Sbjct: 547 EEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKC 606
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
++ KE L EL K+ Y+ D++++ E
Sbjct: 607 EESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRE 647
Score = 48.4 bits (110), Expect = 3e-05
Identities = 52/293 (17%), Positives = 129/293 (44%), Gaps = 18/293 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++ + ++ EK +K ++ + K+ E + LQ+ Q +DL
Sbjct: 100 IDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAE 159
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
++K+ NK + E+Q+ E+ + + +E + K E AQ+ +L+
Sbjct: 160 EDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDL---- 215
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
EN++ + L+ R ++ + QL +++++ + L K E+ ++ +E+E+E
Sbjct: 216 -ENDK--QQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAER 272
Query: 181 ------DRVKSGDAK-ISELEEELKVVGN-SLKSLEVSEEKANQRVEEFXXXXXXXXXXX 232
++ +S A+ + EL E L+ G + +E+++++ + ++
Sbjct: 273 ATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHE 332
Query: 233 XXXXXXXXXXXKTVKKLQKEVD---RLEDELGINKDRYKSLADEMDSTFAELA 282
+V +L +++D R++ +L K +K D++ S+ ++
Sbjct: 333 AMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVS 385
Score = 47.2 bits (107), Expect = 7e-05
Identities = 46/201 (22%), Positives = 96/201 (47%), Gaps = 22/201 (10%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
EQ+ D + + + + EL+K Q+E + + LE+A LE +E ++ + E+
Sbjct: 652 EQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLEL 711
Query: 86 ----AALNRKVQQIEEDLE---KSEERSGTAQQKLLEAQ-QSADENNRMCKVLE------ 131
+ ++RK+ + +E++E ++ +R+ Q L+A+ + A+E R+ K +E
Sbjct: 712 TQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRRANEAIRLKKKMEGDLNEI 771
Query: 132 -------NR-AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
NR A + + + + QLK+ +L +DA +++ +LA VE + + V
Sbjct: 772 EIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEV 831
Query: 184 KSGDAKISELEEELKVVGNSL 204
+ A + + E K+ L
Sbjct: 832 EELRATLEQTERARKLAEQEL 852
Score = 46.0 bits (104), Expect = 2e-04
Identities = 38/154 (24%), Positives = 76/154 (49%), Gaps = 7/154 (4%)
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K++L ++ +E E++L E L +VQ E+L +EER +L++A+
Sbjct: 6 KDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERC----DQLIKAKFQL 61
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ K + RA+ +EE +LT + ++ + D++ LA VE E E
Sbjct: 62 EAK---IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 118
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
++VK+ ++S L+E + + K+L+ + ++A
Sbjct: 119 NKVKNLTEELSGLDETIAKLTREKKALQEAHQQA 152
Score = 44.8 bits (101), Expect = 3e-04
Identities = 44/209 (21%), Positives = 98/209 (46%), Gaps = 15/209 (7%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDL---EEKEKQLTATE 82
EQ+ D+N R + ++ + L ++E DL+ ++++E A++D EEK K+
Sbjct: 849 EQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDA 908
Query: 83 AEVAALNRKVQQIEEDLEKS----EERSGTAQQKLLEAQQSADENNR-MCKVLENRAQQ- 136
A +A +K Q LE+ E+ Q +L EA+Q A + + + LE R ++
Sbjct: 909 AMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIREL 968
Query: 137 ------DEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 190
++++ + L++ ++ +S+E + + ++D ++ + +VKS +
Sbjct: 969 EFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQA 1028
Query: 191 SELEEELKVVGNSLKSLEVSEEKANQRVE 219
E +E+ + + E+A +R +
Sbjct: 1029 EEADEQANAHLTKFRKAQHELEEAEERAD 1057
Score = 42.7 bits (96), Expect = 0.001
Identities = 48/202 (23%), Positives = 96/202 (47%), Gaps = 21/202 (10%)
Query: 37 EKVNEEVRELQKKLAQVEEDLIL---NKNKLE---QANK----DLEEKEKQLTATEAEVA 86
+K +E+ + + K ++EE L+ KN L+ QA D EE+ QL + ++
Sbjct: 3 QKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLE 62
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKL----LEAQQSADENNRMCKVLENRAQQDEERMD 142
A ++V + ED E+ ++KL E ++ D+ +E E ++
Sbjct: 63 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 122
Query: 143 QLTNQLK--EARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 200
LT +L + + + K+ + + + A D+L+ ED+V S + S+LE++++ +
Sbjct: 123 NLTEELSGLDETIAKLTREKKALQEAHQQAL--DDLQAEEDKVNSLNKTKSKLEQQVEDL 180
Query: 201 GNSL---KSLEVSEEKANQRVE 219
+SL K L V E+ +++E
Sbjct: 181 ESSLEQEKKLRVDLERNKRKLE 202
Score = 41.9 bits (94), Expect = 0.002
Identities = 39/201 (19%), Positives = 81/201 (40%), Gaps = 10/201 (4%)
Query: 93 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN------ 146
Q+ +++L KSE + ++KL+ Q ++ + EER DQL
Sbjct: 3 QKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLE 62
Query: 147 -QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
++KE AED + + E++ K +EDE + + + ++++E+E N +K
Sbjct: 63 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 122
Query: 206 SLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLE---DELGI 262
+L ++ + + V L K +LE ++L
Sbjct: 123 NLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLES 182
Query: 263 NKDRYKSLADEMDSTFAELAG 283
+ ++ K L +++ +L G
Sbjct: 183 SLEQEKKLRVDLERNKRKLEG 203
Score = 41.9 bits (94), Expect = 0.002
Identities = 41/198 (20%), Positives = 95/198 (47%), Gaps = 12/198 (6%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+++ ++ R E++ EE+ + A+ E+ +LE+ ++ LEE +T+T+ E
Sbjct: 251 QKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGG-VTSTQIE- 308
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEA---QQSADENNRMCKVLENRAQQDEERMD 142
LN+K + L + E + T Q + + A ++ AD + + ++N Q+ +++++
Sbjct: 309 --LNKKREAEFLKLRRDLEEA-TLQHEAMVATLRKKHADSVAELGEQIDN-LQRVKQKLE 364
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 202
+ + E +L +D + VS+ A +E ED++ K E++ L +
Sbjct: 365 K---EKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTT 421
Query: 203 SLKSLEVSEEKANQRVEE 220
L+ + ++++EE
Sbjct: 422 QKSRLQTEAGELSRQLEE 439
>X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mRNA
for embryonic myosin heavy chain (SMHCE). ).
Length = 1085
Score = 60.1 bits (139), Expect = 9e-09
Identities = 50/217 (23%), Positives = 110/217 (50%), Gaps = 13/217 (5%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKK++ ++ E ++A A E++A+ A A + EE+++ Q A +E +
Sbjct: 873 KKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 929
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN LEQ KDL E ++ L + ++ L +++++E +LE ++++ + + L +
Sbjct: 930 KN-LEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRK 988
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
++ E + + ++ +D+L ++K + AE+AD +++ K + E
Sbjct: 989 YERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHE 1048
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
LE AE+R ++++++L + + +S + SEE
Sbjct: 1049 LEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESEE 1085
Score = 58.4 bits (135), Expect = 3e-08
Identities = 56/254 (22%), Positives = 114/254 (44%), Gaps = 26/254 (10%)
Query: 11 MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE----Q 66
++ E +N +D + C+Q + A + E +EV E + ++ +L K KLE +
Sbjct: 37 VQAESENLLDAEERCDQLIK-AKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE 95
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
KD+++ E L E E A KV+ + E+L +E KL +++ E ++
Sbjct: 96 LKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIA----KLTREKKALQEAHQ- 150
Query: 127 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
+ L++ Q +E++++ L + ED + ++ E +L V +R K
Sbjct: 151 -QALDD-LQAEEDKVNSLNKTKSKLEQQVEDLESSLEQ--------EKKLRVDLERNK-- 198
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTV 246
+LE +LK+ S+ LE +++ ++R+++ K +
Sbjct: 199 ----RKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKI 254
Query: 247 KKLQKEVDRLEDEL 260
K+LQ ++ LE+E+
Sbjct: 255 KELQARIEELEEEI 268
Score = 56.8 bits (131), Expect = 8e-08
Identities = 49/285 (17%), Positives = 120/285 (42%), Gaps = 1/285 (0%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ ++ + A ++ A+ E + ++ N + E K L V+ L
Sbjct: 740 VETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDT 799
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ L+ A + E+ ++QL E L +V+++ LE++E A+Q+LL++ +
Sbjct: 800 QLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERV 859
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L + ++ E + QL +++++A A +A+ K+ + A + +EL+ +
Sbjct: 860 QLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQ 919
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + LE+ +K + + L E ++ + +++++
Sbjct: 920 DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKN 979
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K ++ V L + ++ L D +D ++ Y
Sbjct: 980 TESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSY 1024
Score = 53.6 bits (123), Expect = 8e-07
Identities = 45/261 (17%), Positives = 115/261 (44%), Gaps = 8/261 (3%)
Query: 5 KKKMQAMKLEKDNAMDKADT-CEQQARDANLRAEKVNEEVRELQKKLAQVE---EDLILN 60
+ K + +++ +++A Q+ +D+ + E VN + L+K +++ EDL+++
Sbjct: 518 RTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVD 577
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ L++K++ AE K ++ + +LE S + S + +L + + +
Sbjct: 578 VERANSLAAALDKKQRNFDKVLAE---WKTKCEESQAELEASLKESRSLSTELFKLKNAY 634
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+E + ++ + E+ + LT Q+ E + + ++ + A ++ LE AE
Sbjct: 635 EEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAE 694
Query: 181 DRVKSGDAKISELEEELKVVGNSL-KSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
++ +AKI ++ EL V + + + + +E+ Q +
Sbjct: 695 AALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSR 754
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
+ KK++ +++ +E +L
Sbjct: 755 NEAIRLKKKMEGDLNEIEIQL 775
Score = 53.2 bits (122), Expect = 1e-06
Identities = 55/288 (19%), Positives = 124/288 (43%), Gaps = 22/288 (7%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D + M+++ K N T E Q +A + E++ + EL + ++++ +
Sbjct: 374 IDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEA--- 430
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ ++ LEEKE ++ A ++ ++++ LE+ + A+ L A QS+
Sbjct: 431 ----GELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENK----AKNALAHALQSS 482
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRKLAFV 172
+ C +L + ++++E +L L +A +A+ DA +++E+ +
Sbjct: 483 RHD---CDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 539
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXX 232
L+ +E++V++ +AK + LE+ + + ++ L V E+AN
Sbjct: 540 AQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVL 599
Query: 233 XXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
++ KE L EL K+ Y+ D++++ E
Sbjct: 600 AEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRE 647
Score = 48.4 bits (110), Expect = 3e-05
Identities = 52/293 (17%), Positives = 129/293 (44%), Gaps = 18/293 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++ + ++ EK +K ++ + K+ E + LQ+ Q +DL
Sbjct: 100 IDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAE 159
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
++K+ NK + E+Q+ E+ + + +E + K E AQ+ +L+
Sbjct: 160 EDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDL---- 215
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
EN++ + L+ R ++ + QL +++++ + L K E+ ++ +E+E+E
Sbjct: 216 -ENDK--QQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAER 272
Query: 181 ------DRVKSGDAK-ISELEEELKVVGN-SLKSLEVSEEKANQRVEEFXXXXXXXXXXX 232
++ +S A+ + EL E L+ G + +E+++++ + ++
Sbjct: 273 ATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHE 332
Query: 233 XXXXXXXXXXXKTVKKLQKEVD---RLEDELGINKDRYKSLADEMDSTFAELA 282
+V +L +++D R++ +L K +K D++ S+ ++
Sbjct: 333 AMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVS 385
Score = 46.0 bits (104), Expect = 2e-04
Identities = 38/154 (24%), Positives = 76/154 (49%), Gaps = 7/154 (4%)
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K++L ++ +E E++L E L +VQ E+L +EER +L++A+
Sbjct: 6 KDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERC----DQLIKAKFQL 61
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ K + RA+ +EE +LT + ++ + D++ LA VE E E
Sbjct: 62 EAK---IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 118
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
++VK+ ++S L+E + + K+L+ + ++A
Sbjct: 119 NKVKNLTEELSGLDETIAKLTREKKALQEAHQQA 152
Score = 44.8 bits (101), Expect = 3e-04
Identities = 44/209 (21%), Positives = 98/209 (46%), Gaps = 15/209 (7%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDL---EEKEKQLTATE 82
EQ+ D+N R + ++ + L ++E DL+ ++++E A++D EEK K+
Sbjct: 849 EQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDA 908
Query: 83 AEVAALNRKVQQIEEDLEKS----EERSGTAQQKLLEAQQSADENNR-MCKVLENRAQQ- 136
A +A +K Q LE+ E+ Q +L EA+Q A + + + LE R ++
Sbjct: 909 AMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIREL 968
Query: 137 ------DEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 190
++++ + L++ ++ +S+E + + ++D ++ + +VKS +
Sbjct: 969 EFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQA 1028
Query: 191 SELEEELKVVGNSLKSLEVSEEKANQRVE 219
E +E+ + + E+A +R +
Sbjct: 1029 EEADEQANAHLTKFRKAQHELEEAEERAD 1057
Score = 42.7 bits (96), Expect = 0.001
Identities = 48/202 (23%), Positives = 96/202 (47%), Gaps = 21/202 (10%)
Query: 37 EKVNEEVRELQKKLAQVEEDLIL---NKNKLE---QANK----DLEEKEKQLTATEAEVA 86
+K +E+ + + K ++EE L+ KN L+ QA D EE+ QL + ++
Sbjct: 3 QKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLE 62
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKL----LEAQQSADENNRMCKVLENRAQQDEERMD 142
A ++V + ED E+ ++KL E ++ D+ +E E ++
Sbjct: 63 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 122
Query: 143 QLTNQLK--EARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 200
LT +L + + + K+ + + + A D+L+ ED+V S + S+LE++++ +
Sbjct: 123 NLTEELSGLDETIAKLTREKKALQEAHQQAL--DDLQAEEDKVNSLNKTKSKLEQQVEDL 180
Query: 201 GNSL---KSLEVSEEKANQRVE 219
+SL K L V E+ +++E
Sbjct: 181 ESSLEQEKKLRVDLERNKRKLE 202
Score = 41.9 bits (94), Expect = 0.002
Identities = 39/201 (19%), Positives = 81/201 (40%), Gaps = 10/201 (4%)
Query: 93 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN------ 146
Q+ +++L KSE + ++KL+ Q ++ + EER DQL
Sbjct: 3 QKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLE 62
Query: 147 -QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
++KE AED + + E++ K +EDE + + + ++++E+E N +K
Sbjct: 63 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 122
Query: 206 SLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLE---DELGI 262
+L ++ + + V L K +LE ++L
Sbjct: 123 NLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLES 182
Query: 263 NKDRYKSLADEMDSTFAELAG 283
+ ++ K L +++ +L G
Sbjct: 183 SLEQEKKLRVDLERNKRKLEG 203
Score = 41.9 bits (94), Expect = 0.002
Identities = 41/198 (20%), Positives = 95/198 (47%), Gaps = 12/198 (6%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+++ ++ R E++ EE+ + A+ E+ +LE+ ++ LEE +T+T+ E
Sbjct: 251 QKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGG-VTSTQIE- 308
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEA---QQSADENNRMCKVLENRAQQDEERMD 142
LN+K + L + E + T Q + + A ++ AD + + ++N Q+ +++++
Sbjct: 309 --LNKKREAEFLKLRRDLEEA-TLQHEAMVATLRKKHADSVAELGEQIDN-LQRVKQKLE 364
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 202
+ + E +L +D + VS+ A +E ED++ K E++ L +
Sbjct: 365 K---EKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTT 421
Query: 203 SLKSLEVSEEKANQRVEE 220
L+ + ++++EE
Sbjct: 422 QKSRLQTEAGELSRQLEE 439
>X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for
embryonic myosin heavy chain. ).
Length = 1940
Score = 60.1 bits (139), Expect = 9e-09
Identities = 50/217 (23%), Positives = 110/217 (50%), Gaps = 13/217 (5%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKK++ ++ E ++A A E++A+ A A + EE+++ Q A +E +
Sbjct: 1728 KKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 1784
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN LEQ KDL E ++ L + ++ L +++++E +LE ++++ + + L +
Sbjct: 1785 KN-LEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRK 1843
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
++ E + + ++ +D+L ++K + AE+AD +++ K + E
Sbjct: 1844 YERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHE 1903
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
LE AE+R ++++++L + + +S + SEE
Sbjct: 1904 LEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESEE 1940
Score = 58.4 bits (135), Expect = 3e-08
Identities = 56/254 (22%), Positives = 114/254 (44%), Gaps = 26/254 (10%)
Query: 11 MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE----Q 66
++ E +N +D + C+Q + A + E +EV E + ++ +L K KLE +
Sbjct: 892 VQAESENLLDAEERCDQLIK-AKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE 950
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
KD+++ E L E E A KV+ + E+L +E KL +++ E ++
Sbjct: 951 LKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIA----KLTREKKALQEAHQ- 1005
Query: 127 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
+ L++ Q +E++++ L + ED + ++ E +L V +R K
Sbjct: 1006 -QALDD-LQAEEDKVNSLNKTKSKLEQQVEDLESSLEQ--------EKKLRVDLERNK-- 1053
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTV 246
+LE +LK+ S+ LE +++ ++R+++ K +
Sbjct: 1054 ----RKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKI 1109
Query: 247 KKLQKEVDRLEDEL 260
K+LQ ++ LE+E+
Sbjct: 1110 KELQARIEELEEEI 1123
Score = 56.8 bits (131), Expect = 8e-08
Identities = 49/285 (17%), Positives = 120/285 (42%), Gaps = 1/285 (0%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ ++ + A ++ A+ E + ++ N + E K L V+ L
Sbjct: 1595 VETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDT 1654
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ L+ A + E+ ++QL E L +V+++ LE++E A+Q+LL++ +
Sbjct: 1655 QLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERV 1714
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L + ++ E + QL +++++A A +A+ K+ + A + +EL+ +
Sbjct: 1715 QLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQ 1774
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + LE+ +K + + L E ++ + +++++
Sbjct: 1775 DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKN 1834
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K ++ V L + ++ L D +D ++ Y
Sbjct: 1835 TESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSY 1879
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/261 (17%), Positives = 116/261 (44%), Gaps = 8/261 (3%)
Query: 5 KKKMQAMKLEKDNAMDKA-DTCEQQARDANLRAEKVNEEVRELQKKLAQVE---EDLILN 60
+ K + +++ +++A + Q+ +D+ + E VN + L+K +++ EDL+++
Sbjct: 1373 RTKYETDAIQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVD 1432
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ L++K++ AE K ++ + +LE S + S + +L + + +
Sbjct: 1433 VERANSLAAALDKKQRNFDKVLAE---WKTKCEESQAELEASLKESRSLSTELFKLKNAY 1489
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+E + ++ + E+ + LT Q+ E + + ++ + A ++ LE AE
Sbjct: 1490 EEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAE 1549
Query: 181 DRVKSGDAKISELEEELKVVGNSL-KSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
++ +AKI ++ EL V + + + + +E+ Q +
Sbjct: 1550 AALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSR 1609
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
+ KK++ +++ +E +L
Sbjct: 1610 NEAIRLKKKMEGDLNEIEIQL 1630
Score = 54.4 bits (125), Expect = 4e-07
Identities = 42/170 (24%), Positives = 86/170 (50%), Gaps = 7/170 (4%)
Query: 45 ELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 104
E +K++A ++E+ K++L ++ +E E++L E L +VQ E+L +EE
Sbjct: 845 ETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEE 904
Query: 105 RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 164
R +L++A+ + K + RA+ +EE +LT + ++ + D+
Sbjct: 905 RC----DQLIKAKFQLEAK---IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 957
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
+ LA VE E E++VK+ ++S L+E + + K+L+ + ++A
Sbjct: 958 LELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQA 1007
Score = 53.6 bits (123), Expect = 8e-07
Identities = 51/274 (18%), Positives = 121/274 (44%), Gaps = 20/274 (7%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D + M+++ K N T E Q +A + E++ + EL + ++++ +
Sbjct: 1229 IDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEA--- 1285
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ ++ LEEKE ++ A ++ ++++ LE+ + A+ L A QS+
Sbjct: 1286 ----GELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENK----AKNALAHALQSS 1337
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ C +L + ++++E +L L +A +E A ++ + + E ELE A+
Sbjct: 1338 RHD---CDLLREQYEEEQEGKAELQRALSKAN--SEVAQWRTKYETDAIQRTE-ELEEAQ 1391
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+++ ++ + EE+++ V SLE ++++ VE+
Sbjct: 1392 EKLAQ---RLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQR 1448
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
K + + + + + + EL + +SL+ E+
Sbjct: 1449 NFDKVLAEWKTKCEESQAELEASLKESRSLSTEL 1482
Score = 48.4 bits (110), Expect = 3e-05
Identities = 52/293 (17%), Positives = 129/293 (44%), Gaps = 18/293 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++ + ++ EK +K ++ + K+ E + LQ+ Q +DL
Sbjct: 955 IDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAE 1014
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
++K+ NK + E+Q+ E+ + + +E + K E AQ+ +L+
Sbjct: 1015 EDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDL---- 1070
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
EN++ + L+ R ++ + QL +++++ + L K E+ ++ +E+E+E
Sbjct: 1071 -ENDK--QQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAER 1127
Query: 181 ------DRVKSGDAK-ISELEEELKVVGN-SLKSLEVSEEKANQRVEEFXXXXXXXXXXX 232
++ +S A+ + EL E L+ G + +E+++++ + ++
Sbjct: 1128 ATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHE 1187
Query: 233 XXXXXXXXXXXKTVKKLQKEVD---RLEDELGINKDRYKSLADEMDSTFAELA 282
+V +L +++D R++ +L K +K D++ S+ ++
Sbjct: 1188 AMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVS 1240
Score = 44.8 bits (101), Expect = 3e-04
Identities = 44/209 (21%), Positives = 98/209 (46%), Gaps = 15/209 (7%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDL---EEKEKQLTATE 82
EQ+ D+N R + ++ + L ++E DL+ ++++E A++D EEK K+
Sbjct: 1704 EQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDA 1763
Query: 83 AEVAALNRKVQQIEEDLEKS----EERSGTAQQKLLEAQQSADENNR-MCKVLENRAQQ- 136
A +A +K Q LE+ E+ Q +L EA+Q A + + + LE R ++
Sbjct: 1764 AMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIREL 1823
Query: 137 ------DEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 190
++++ + L++ ++ +S+E + + ++D ++ + +VKS +
Sbjct: 1824 EFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQA 1883
Query: 191 SELEEELKVVGNSLKSLEVSEEKANQRVE 219
E +E+ + + E+A +R +
Sbjct: 1884 EEADEQANAHLTKFRKAQHELEEAEERAD 1912
Score = 43.2 bits (97), Expect = 0.001
Identities = 50/218 (22%), Positives = 101/218 (46%), Gaps = 21/218 (9%)
Query: 21 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL---NKNKLE---QANK----D 70
K+ E++ +K +E+ + + K ++EE L+ KN L+ QA D
Sbjct: 842 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLD 901
Query: 71 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL----LEAQQSADENNRM 126
EE+ QL + ++ A ++V + ED E+ ++KL E ++ D+
Sbjct: 902 AEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 961
Query: 127 CKVLENRAQQDEERMDQLTNQLK--EARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
+E E ++ LT +L + + + K+ + + + A D+L+ ED+V
Sbjct: 962 LAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQAL--DDLQAEEDKVN 1019
Query: 185 SGDAKISELEEELKVVGNSL---KSLEVSEEKANQRVE 219
S + S+LE++++ + +SL K L V E+ +++E
Sbjct: 1020 SLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLE 1057
Score = 41.9 bits (94), Expect = 0.002
Identities = 41/198 (20%), Positives = 95/198 (47%), Gaps = 12/198 (6%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+++ ++ R E++ EE+ + A+ E+ +LE+ ++ LEE +T+T+ E
Sbjct: 1106 QKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGG-VTSTQIE- 1163
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEA---QQSADENNRMCKVLENRAQQDEERMD 142
LN+K + L + E + T Q + + A ++ AD + + ++N Q+ +++++
Sbjct: 1164 --LNKKREAEFLKLRRDLEEA-TLQHEAMVATLRKKHADSVAELGEQIDN-LQRVKQKLE 1219
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 202
+ + E +L +D + VS+ A +E ED++ K E++ L +
Sbjct: 1220 K---EKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTT 1276
Query: 203 SLKSLEVSEEKANQRVEE 220
L+ + ++++EE
Sbjct: 1277 QKSRLQTEAGELSRQLEE 1294
>X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 AA)
protein.
Length = 1167
Score = 60.1 bits (139), Expect = 9e-09
Identities = 50/217 (23%), Positives = 110/217 (50%), Gaps = 13/217 (5%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKK++ ++ E ++A A E++A+ A A + EE+++ Q A +E +
Sbjct: 955 KKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 1011
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN LEQ KDL E ++ L + ++ L +++++E +LE ++++ + + L +
Sbjct: 1012 KN-LEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRK 1070
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
++ E + + ++ +D+L ++K + AE+AD +++ K + E
Sbjct: 1071 YERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHE 1130
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
LE AE+R ++++++L + + +S + SEE
Sbjct: 1131 LEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESEE 1167
Score = 58.4 bits (135), Expect = 3e-08
Identities = 56/254 (22%), Positives = 114/254 (44%), Gaps = 26/254 (10%)
Query: 11 MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE----Q 66
++ E +N +D + C+Q + A + E +EV E + ++ +L K KLE +
Sbjct: 119 VQAESENLLDAEERCDQLIK-AKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE 177
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
KD+++ E L E E A KV+ + E+L +E KL +++ E ++
Sbjct: 178 LKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIA----KLTREKKALQEAHQ- 232
Query: 127 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
+ L++ Q +E++++ L + ED + ++ E +L V +R K
Sbjct: 233 -QALDD-LQAEEDKVNSLNKTKSKLEQQVEDLESSLEQ--------EKKLRVDLERNK-- 280
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTV 246
+LE +LK+ S+ LE +++ ++R+++ K +
Sbjct: 281 ----RKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKI 336
Query: 247 KKLQKEVDRLEDEL 260
K+LQ ++ LE+E+
Sbjct: 337 KELQARIEELEEEI 350
Score = 56.4 bits (130), Expect = 1e-07
Identities = 49/285 (17%), Positives = 120/285 (42%), Gaps = 1/285 (0%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ ++ + A ++ A+ E + ++ N + E K L V+ L
Sbjct: 822 VETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDT 881
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ L+ A + E+ ++QL E L +V+++ LE++E A+Q+LL++ +
Sbjct: 882 QLHLDDALQTQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERV 941
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L + ++ E + QL +++++A A +A+ K+ + A + +EL+ +
Sbjct: 942 QLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQ 1001
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + LE+ +K + + L E ++ + +++++
Sbjct: 1002 DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKN 1061
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K ++ V L + ++ L D +D ++ Y
Sbjct: 1062 TESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSY 1106
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/261 (17%), Positives = 116/261 (44%), Gaps = 8/261 (3%)
Query: 5 KKKMQAMKLEKDNAMDKA-DTCEQQARDANLRAEKVNEEVRELQKKLAQVE---EDLILN 60
+ K + +++ +++A + Q+ +D+ + E VN + L+K +++ EDL+++
Sbjct: 600 RTKYETDAIQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVD 659
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ L++K++ AE K ++ + +LE S + S + +L + + +
Sbjct: 660 VERANSLAAALDKKQRNFDKVLAE---WKTKCEESQAELEASLKESRSLSTELFKLKNAY 716
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+E + ++ + E+ + LT Q+ E + + ++ + A ++ LE AE
Sbjct: 717 EEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAE 776
Query: 181 DRVKSGDAKISELEEELKVVGNSL-KSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
++ +AKI ++ EL V + + + + +E+ Q +
Sbjct: 777 AALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSR 836
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
+ KK++ +++ +E +L
Sbjct: 837 NEAIRLKKKMEGDLNEIEIQL 857
Score = 54.4 bits (125), Expect = 4e-07
Identities = 42/170 (24%), Positives = 86/170 (50%), Gaps = 7/170 (4%)
Query: 45 ELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 104
E +K++A ++E+ K++L ++ +E E++L E L +VQ E+L +EE
Sbjct: 72 ETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEE 131
Query: 105 RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 164
R +L++A+ + K + RA+ +EE +LT + ++ + D+
Sbjct: 132 RC----DQLIKAKFQLEAK---IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 184
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
+ LA VE E E++VK+ ++S L+E + + K+L+ + ++A
Sbjct: 185 LELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQA 234
Score = 53.6 bits (123), Expect = 8e-07
Identities = 51/274 (18%), Positives = 121/274 (44%), Gaps = 20/274 (7%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D + M+++ K N T E Q +A + E++ + EL + ++++ +
Sbjct: 456 IDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEA--- 512
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ ++ LEEKE ++ A ++ ++++ LE+ + A+ L A QS+
Sbjct: 513 ----GELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENK----AKNALAHALQSS 564
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ C +L + ++++E +L L +A +E A ++ + + E ELE A+
Sbjct: 565 RHD---CDLLREQYEEEQEGKAELQRALSKAN--SEVAQWRTKYETDAIQRTE-ELEEAQ 618
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
+++ ++ + EE+++ V SLE ++++ VE+
Sbjct: 619 EKLAQ---RLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQR 675
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
K + + + + + + EL + +SL+ E+
Sbjct: 676 NFDKVLAEWKTKCEESQAELEASLKESRSLSTEL 709
Score = 48.4 bits (110), Expect = 3e-05
Identities = 52/293 (17%), Positives = 129/293 (44%), Gaps = 18/293 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++ + ++ EK +K ++ + K+ E + LQ+ Q +DL
Sbjct: 182 IDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAE 241
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
++K+ NK + E+Q+ E+ + + +E + K E AQ+ +L+
Sbjct: 242 EDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDL---- 297
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
EN++ + L+ R ++ + QL +++++ + L K E+ ++ +E+E+E
Sbjct: 298 -ENDK--QQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAER 354
Query: 181 ------DRVKSGDAK-ISELEEELKVVGN-SLKSLEVSEEKANQRVEEFXXXXXXXXXXX 232
++ +S A+ + EL E L+ G + +E+++++ + ++
Sbjct: 355 ATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHE 414
Query: 233 XXXXXXXXXXXKTVKKLQKEVD---RLEDELGINKDRYKSLADEMDSTFAELA 282
+V +L +++D R++ +L K +K D++ S+ ++
Sbjct: 415 AMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVS 467
Score = 44.8 bits (101), Expect = 3e-04
Identities = 44/209 (21%), Positives = 98/209 (46%), Gaps = 15/209 (7%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDL---EEKEKQLTATE 82
EQ+ D+N R + ++ + L ++E DL+ ++++E A++D EEK K+
Sbjct: 931 EQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDA 990
Query: 83 AEVAALNRKVQQIEEDLEKS----EERSGTAQQKLLEAQQSADENNR-MCKVLENRAQQ- 136
A +A +K Q LE+ E+ Q +L EA+Q A + + + LE R ++
Sbjct: 991 AMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIREL 1050
Query: 137 ------DEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 190
++++ + L++ ++ +S+E + + ++D ++ + +VKS +
Sbjct: 1051 EFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQA 1110
Query: 191 SELEEELKVVGNSLKSLEVSEEKANQRVE 219
E +E+ + + E+A +R +
Sbjct: 1111 EEADEQANAHLTKFRKAQHELEEAEERAD 1139
Score = 43.2 bits (97), Expect = 0.001
Identities = 50/218 (22%), Positives = 101/218 (46%), Gaps = 21/218 (9%)
Query: 21 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL---NKNKLE---QANK----D 70
K+ E++ +K +E+ + + K ++EE L+ KN L+ QA D
Sbjct: 69 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLD 128
Query: 71 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL----LEAQQSADENNRM 126
EE+ QL + ++ A ++V + ED E+ ++KL E ++ D+
Sbjct: 129 AEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 188
Query: 127 CKVLENRAQQDEERMDQLTNQLK--EARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
+E E ++ LT +L + + + K+ + + + A D+L+ ED+V
Sbjct: 189 LAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQAL--DDLQAEEDKVN 246
Query: 185 SGDAKISELEEELKVVGNSL---KSLEVSEEKANQRVE 219
S + S+LE++++ + +SL K L V E+ +++E
Sbjct: 247 SLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLE 284
Score = 41.9 bits (94), Expect = 0.002
Identities = 41/198 (20%), Positives = 95/198 (47%), Gaps = 12/198 (6%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+++ ++ R E++ EE+ + A+ E+ +LE+ ++ LEE +T+T+ E
Sbjct: 333 QKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGG-VTSTQIE- 390
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEA---QQSADENNRMCKVLENRAQQDEERMD 142
LN+K + L + E + T Q + + A ++ AD + + ++N Q+ +++++
Sbjct: 391 --LNKKREAEFLKLRRDLEEA-TLQHEAMVATLRKKHADSVAELGEQIDN-LQRVKQKLE 446
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 202
+ + E +L +D + VS+ A +E ED++ K E++ L +
Sbjct: 447 K---EKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTT 503
Query: 203 SLKSLEVSEEKANQRVEE 220
L+ + ++++EE
Sbjct: 504 QKSRLQTEAGELSRQLEE 521
>U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein.
Length = 3113
Score = 60.1 bits (139), Expect = 9e-09
Identities = 49/276 (17%), Positives = 120/276 (43%), Gaps = 7/276 (2%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D +K +++ ++ E + A + +A ++ E + ++ + + L +E D++ +
Sbjct: 2331 DLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIR 2390
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ E +L++++++++ E ++ +Q+ E++ + +E+S TA + L Q
Sbjct: 2391 SEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEML---QTQLK 2447
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E N L N + + + L++Q++ L DE ++ +
Sbjct: 2448 ELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQ 2507
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXX 241
V+ G K+ + +EE+ + N ++ E K +Q E
Sbjct: 2508 EVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELE-- 2565
Query: 242 XXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDST 277
+ ++ LQ + L+D L + + YK+L +E++ T
Sbjct: 2566 --QKIQVLQSKNASLQDTLEVLQSSYKNLENELELT 2599
Score = 56.8 bits (131), Expect = 8e-08
Identities = 46/222 (20%), Positives = 101/222 (45%), Gaps = 14/222 (6%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-------QKKLAQVE 54
+ +K+K Q ++ + + E + ++ + ++ +V EL Q+KL +E
Sbjct: 1981 EKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLE 2040
Query: 55 ED---LILNK----NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 107
+D L L K N++ Q NK+ E K+ + +A ++ + + + + LE + G
Sbjct: 2041 KDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKG 2100
Query: 108 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 167
+L Q+ + R + L R + DE++ + +LKE + K + + R
Sbjct: 2101 EFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLER 2160
Query: 168 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 209
+L E+ E+ ++ A++ L+ +++ + SLK E+
Sbjct: 2161 ELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFEL 2202
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/218 (17%), Positives = 96/218 (44%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D++K K++ ++ E + + + A ++ E + ++ E+ + L E DL+ +
Sbjct: 2149 DSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 2208
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ E K ++EK+ QL+ + +++ +++ E+ + +E S TA + L + +
Sbjct: 2209 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELN 2268
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E + + E+ +D + + R E + + +K V +L+ +E
Sbjct: 2269 EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEH 2328
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
++ LE EL++ + + + E + VE
Sbjct: 2329 HADLLKGRVENLERELEIARTNQEHAALEAENSKGEVE 2366
Score = 54.0 bits (124), Expect = 6e-07
Identities = 56/278 (20%), Positives = 116/278 (41%), Gaps = 9/278 (3%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 65
+K + +EK+ ++K C + + ++ + + L++KL ++ EDL + E
Sbjct: 323 EKAKVELIEKEKVLNK---CRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAE 379
Query: 66 QANKDLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
A LE+K K+ + E++ R Q ++++ + + R Q+L +A+ +
Sbjct: 380 SARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKAR---LTQELQQAKNMHNVLQ 436
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
L + QQ E +++ +L A + + K +E+ R + ++ E + + +
Sbjct: 437 AELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSE 496
Query: 185 SGDAKISELEEELKVVGNSL-KSLEVSEE-KANQRVEEFXXXXXXXXXXXXXXXXXXXXX 242
++ LE ELK + L +S +EE KA +E
Sbjct: 497 QKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKL 556
Query: 243 XKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
V L+K+ D +D L + + L D++ T E
Sbjct: 557 KLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKE 594
Score = 54.0 bits (124), Expect = 6e-07
Identities = 52/282 (18%), Positives = 117/282 (41%), Gaps = 11/282 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED---L 57
+D + KK A+ + +K E + + EV+E + L + D L
Sbjct: 1966 LDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSEL 2025
Query: 58 ILNKNKLEQANKDLEEKEKQLTATEAE----VAALNRKVQQIEEDLEKSEERSGTAQQKL 113
+ +K L++ + LE+ + L+ T+ E +A LN++ + + ++ E + R + +
Sbjct: 2026 LKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEK 2085
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
L ++ + R +E + QL +++ R+ E + K ++ KL E
Sbjct: 2086 LNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERE 2145
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXX 233
E + +D+V++ + ++ EE ++V ++ + E ++EE
Sbjct: 2146 RENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLV 2205
Query: 234 XXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMD 275
K +++ Q ++ L+ L +KSL +E +
Sbjct: 2206 TLRSEKENLTKQIQEKQGQLSELDKLL----SSFKSLLEEKE 2243
Score = 46.8 bits (106), Expect = 9e-05
Identities = 41/223 (18%), Positives = 98/223 (43%), Gaps = 4/223 (1%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
++++ ++ EK N + + + LR EEV +L++ + ++ + ++
Sbjct: 2072 ESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADE 2131
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
K + L+E+E++ + + +V L R++Q EE+ E + ++ ++ + +
Sbjct: 2132 KKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIE 2191
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED-ELEVAE 180
E R KV E + LT Q++E + + D L E E+++ E
Sbjct: 2192 EMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKE 2251
Query: 181 D---RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ V+ ++ EL E + + + ++ +E+ + +EE
Sbjct: 2252 ESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEE 2294
Score = 46.4 bits (105), Expect = 1e-04
Identities = 45/223 (20%), Positives = 96/223 (43%), Gaps = 15/223 (6%)
Query: 65 EQANKDLEEKEKQLTATEA--EVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
EQ + E E +L A ++ A L +V +E LE ++ + Q++ E Q E
Sbjct: 802 EQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGE 861
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED---ELEVA 179
+ EN + ++ + + L ED + V+ L+ +E+ EL++
Sbjct: 862 ------IEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLL 915
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D+V++ A+I EL++ ++ +SLK L++ E + +E
Sbjct: 916 NDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQEN 975
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
T+K++ +++ + L + + + DE + + +EL+
Sbjct: 976 G----TLKEINASLNQEKMNLIQKSESFANYIDEREKSISELS 1014
Score = 44.0 bits (99), Expect = 6e-04
Identities = 46/258 (17%), Positives = 97/258 (37%), Gaps = 9/258 (3%)
Query: 16 DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKE 75
DN D+ +++ D ++ E ++ + +E DL + + + KD E K+
Sbjct: 1883 DNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQ 1942
Query: 76 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 135
K + E E++ + + Q+ +L+ T +K Q +++ + LE+
Sbjct: 1943 KVIVCLEEELSVVTSERNQLRGELD-------TMSKKTTALDQLSEKMKEKTQELESHQS 1995
Query: 136 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 195
+ + ++KE L + E+ + ++++L+ E ++ ELE
Sbjct: 1996 ECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELEN 2055
Query: 196 ELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDR 255
++ + + L E R+ E + Q+EV +
Sbjct: 2056 QIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQ 2115
Query: 256 LEDELGINKDRYKSLADE 273
L GI K R + ADE
Sbjct: 2116 L--RRGIEKLRVRIEADE 2131
Score = 40.7 bits (91), Expect = 0.006
Identities = 40/189 (21%), Positives = 80/189 (42%), Gaps = 3/189 (1%)
Query: 33 NLRAEKVNEEVRELQKKLAQVEEDLILNKNK-LEQANKDLEEKEKQLTATEAEVAALNRK 91
+L EK E++ ++ VE ++ N+ K L +A L ++ + ATE + +
Sbjct: 2237 SLLEEKEQAEIQIKEESKTAVE--MLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEE 2294
Query: 92 VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA 151
Q+ +EK R ++K L Q E+ +L+ R + E ++ + A
Sbjct: 2295 EHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHA 2354
Query: 152 RLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSE 211
L AE++ G+ + + K+ + L E V + ++ L EL+ + LE+
Sbjct: 2355 ALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIIN 2414
Query: 212 EKANQRVEE 220
++E
Sbjct: 2415 SSFENILQE 2423
Score = 39.9 bits (89), Expect = 0.010
Identities = 28/120 (23%), Positives = 57/120 (47%), Gaps = 3/120 (2%)
Query: 99 LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL---A 155
L+K +E G + E QQ + + + + + Q+ E + TN +E + L
Sbjct: 17 LQKIQELEGQLDKLKKEKQQRQFQLDSLEAAPQKQTQKVENEKTEGTNLKRENQRLMEIC 76
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
E + ++S +L E ++ E ++ SG +I +LE+ELK + L+ + + + A+
Sbjct: 77 ESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSAD 136
Score = 39.9 bits (89), Expect = 0.010
Identities = 33/127 (25%), Positives = 67/127 (52%), Gaps = 11/127 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D +KK+ Q + + D+ +A +Q + N + E N + RE Q+ L ++ E L
Sbjct: 27 LDKLKKEKQQRQFQLDSL--EAAPQKQTQKVENEKTEGTNLK-RENQR-LMEICESLEKT 82
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K K+ +L+ KE Q+ E ++ + ++++++E++L++ + +QQ A QSA
Sbjct: 83 KQKISH---ELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQ----AAQSA 135
Query: 121 DENNRMC 127
D + C
Sbjct: 136 DVSLNPC 142
Score = 37.5 bits (83), Expect = 0.053
Identities = 52/216 (24%), Positives = 102/216 (47%), Gaps = 38/216 (17%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE-------EKEK-------QLTATE 82
+++ ++ EL+ +L E+++ NK ++ LE EKEK +L T
Sbjct: 288 QELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTT 347
Query: 83 AE-------VAALNRKVQQIEEDL----EKSEERSGTAQQKLLEAQQS-ADENNRMCKVL 130
A+ AL +K++++ EDL + +E + +QK+ E ++ +E +R +
Sbjct: 348 AQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSF 407
Query: 131 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV-------AEDRV 183
+ Q+ + +LT +L++A+ + + D+++ +E+ LE AE
Sbjct: 408 QTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAF 467
Query: 184 KSGDAKISELE---EELKVVGNSLKSLEVSEEKANQ 216
++ K +EL EE+K N LKS SE+KA +
Sbjct: 468 QASQIKENELRRSMEEMKKENNLLKS--HSEQKARE 501
Score = 37.5 bits (83), Expect = 0.053
Identities = 40/176 (22%), Positives = 84/176 (47%), Gaps = 15/176 (8%)
Query: 41 EEVRELQKKLAQVEEDL-ILNKNKLEQANKDLEE-KEKQLTATEAEVAALNRKVQQIEED 98
++++EL + +++++ L ++K+++E+ K EE E QL EAE +K Q + D
Sbjct: 2661 DQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAE-----KKHQALLLD 2715
Query: 99 LEKSEE-RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 157
K E T ++KL ++ +L++ ++ L N LK + E+
Sbjct: 2716 TNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEE-------LNNSLKATTQILEE 2768
Query: 158 ADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
+ + + ++ E E A+ ++K +LEEE +++ L L+ ++EK
Sbjct: 2769 LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEK 2824
Score = 37.1 bits (82), Expect = 0.070
Identities = 41/183 (22%), Positives = 87/183 (47%), Gaps = 17/183 (9%)
Query: 34 LRAEKVNEE-VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 92
++AE++++ V E +++++++ED ++N + + LE KEK E+ LN KV
Sbjct: 867 MKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEK-------ELQLLNDKV 919
Query: 93 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
+ + ++++ ++ + + L E Q ++ + K + + ++ +++LT +E
Sbjct: 920 ETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELT---QENG 976
Query: 153 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
L E + E + E ++R KS ISEL ++ K L L+ EE
Sbjct: 977 TLKEINASLNQEKMNLIQKSESFANYIDEREKS----ISELSDQYK--QEKLILLQRCEE 1030
Query: 213 KAN 215
N
Sbjct: 1031 TGN 1033
Score = 36.7 bits (81), Expect = 0.092
Identities = 50/183 (27%), Positives = 91/183 (49%), Gaps = 20/183 (10%)
Query: 6 KKMQAMKLEKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
++M+A ++ + D + QQ + +L EK+ V +L+K+ ++ L ++ +
Sbjct: 524 EEMKAKNTSQETMLRDLQEKINQQ--ENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHI 581
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ-QKLLEAQQSADEN 123
EQ N L + EK+ ++A ++AL K ++ E EK+ ++ +KLL +S EN
Sbjct: 582 EQLNDKLSKTEKE---SKALLSALELKKKEYELKEEKTLFSCWKSENEKLLTQMESEKEN 638
Query: 124 -----NRM--C-KVLENRAQQDEERMDQL----TNQLKEARLLAEDADGKSDEV-SRKLA 170
N + C K + ++ + ER+ L N E R L D KS EV ++KLA
Sbjct: 639 LQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLA 698
Query: 171 FVE 173
++E
Sbjct: 699 YME 701
Score = 36.7 bits (81), Expect = 0.092
Identities = 57/269 (21%), Positives = 104/269 (38%), Gaps = 25/269 (9%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
++K+Q MK + AM+ T ++ + E + ++ L+ E L L K +L
Sbjct: 2426 QEKVQ-MKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQL 2484
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
Q L+E + ++ V L ++V+ ++ LEK +E + ++ + +Q
Sbjct: 2485 LQG---LDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQ------ 2535
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
L ++ Q E Q E R L + + K + K A ++D LEV + K
Sbjct: 2536 -----LVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYK 2590
Query: 185 SGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXK 244
+ LE EL++ S EK N+ +
Sbjct: 2591 N-------LENELELTKMDKMSF---VEKVNKMTAKETELQREMHEMAQKTAELQEELSG 2640
Query: 245 TVKKLQKEVDRLEDELGINKDRYKSLADE 273
+L E+ L +E+ +KD+ K L E
Sbjct: 2641 EKNRLAGELQLLLEEIKSSKDQLKELTLE 2669
Score = 36.3 bits (80), Expect = 0.12
Identities = 45/215 (20%), Positives = 87/215 (40%), Gaps = 8/215 (3%)
Query: 13 LEKDNA-MDKADTC-EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKD 70
LEKDN K C E++ ++ E+ + KK +++ K K ++
Sbjct: 1934 LEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESH 1993
Query: 71 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
E + EAEV +Q + D+ + + Q+KL ++ + + L
Sbjct: 1994 QSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCEL 2053
Query: 131 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 190
EN+ Q + + L + + + ++D + VS+ L E R+ S ++
Sbjct: 2054 ENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEV 2113
Query: 191 SELE---EELKV--VGNSLKSLEVSEEKANQRVEE 220
+L E+L+V + K L ++ EK +R E
Sbjct: 2114 HQLRRGIEKLRVRIEADEKKQLHIA-EKLKERERE 2147
Score = 35.9 bits (79), Expect = 0.16
Identities = 33/139 (23%), Positives = 54/139 (38%)
Query: 82 EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
E EV +Q + D S + ++ L + + E LE R Q E+ M
Sbjct: 249 EQEVTPSRSTLQIGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEM 308
Query: 142 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 201
N+ +E +L E A + E + L DEL + K + LE++LK +
Sbjct: 309 KGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLT 368
Query: 202 NSLKSLEVSEEKANQRVEE 220
L + E A +E+
Sbjct: 369 EDLSCQRQNAESARCSLEQ 387
Score = 35.1 bits (77), Expect = 0.28
Identities = 47/276 (17%), Positives = 115/276 (41%), Gaps = 10/276 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ +++ K++K + ++K + + + ++ ++ ELQ++L+ + L
Sbjct: 2592 LENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQL 2651
Query: 64 LEQANKDLEEKEKQLTATEAEV-AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS--- 119
L + K +++ K+LT +E+ +L+ + E K E Q +L EA++
Sbjct: 2652 LLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQA 2711
Query: 120 --ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
D N + ++ ++ + + L++Q E LL + ++ + +E+ +
Sbjct: 2712 LLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKK 2771
Query: 178 VAEDRVKSGDAKISELEE---ELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXX 234
D +K + E E ++K++ S K LE +E + + +
Sbjct: 2772 TKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVM 2831
Query: 235 XXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSL 270
+ +K+L++ ++ E D+Y SL
Sbjct: 2832 DTKVDELTTE-IKELKETLEEKTKEADEYLDKYCSL 2866
Score = 34.7 bits (76), Expect = 0.37
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 8/134 (5%)
Query: 42 EVRELQKKLAQVEE-DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 100
E+ EL ++ ++E + LN+ K+ K E + E ++ L+ + +Q + L
Sbjct: 967 EIEELTQENGTLKEINASLNQEKMNLIQKS-ESFANYIDEREKSISELSDQYKQEKLILL 1025
Query: 101 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+ E +G A + L + ++A E N + L N E QLKEA A++
Sbjct: 1026 QRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEA--FAKE--- 1080
Query: 161 KSDEVSRKLAFVED 174
E KLAF E+
Sbjct: 1081 -HQEFLTKLAFAEE 1093
Score = 32.3 bits (70), Expect = 2.0
Identities = 53/238 (22%), Positives = 112/238 (47%), Gaps = 20/238 (8%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARD---ANLRAEK--VNEEVRELQKKLAQVEED 56
D +K K ++ +D+ +Q A AN+ E+ + E E + + Q ++
Sbjct: 764 DLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSERSECRLEADQSPKN 823
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE--RSGTAQ--QK 112
+ +N+++ LE +++ + + + L + +IEE+L K+E+ +S A+ Q+
Sbjct: 824 SAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQR 883
Query: 113 LLEAQQ--SADEN--NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
+ + Q+ SA +N LEN+ ++ + D++ + E + L + D + ++
Sbjct: 884 ISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSL-KE 942
Query: 169 LAFVEDELEVAEDRVKSGDAKISELE-EELKVVGNSLKSLEVS--EEKAN--QRVEEF 221
L + + L + E + S +++ E EEL +LK + S +EK N Q+ E F
Sbjct: 943 LQLLSETLSL-EKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESF 999
Score = 31.9 bits (69), Expect = 2.6
Identities = 30/159 (18%), Positives = 71/159 (44%), Gaps = 3/159 (1%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
+K + M+ EK+N K + E + +++ + NE VR L+ + ++ N L
Sbjct: 626 EKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVL 685
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ + ++E ++ + + ++K Q +IE K+ + +G + + Q ++E
Sbjct: 686 DSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEI 745
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
+ ++ + E D L + K+A L+ + +S
Sbjct: 746 MDKDRCYQDLHAEYESLRDLLKS--KDASLVTNEDHQRS 782
Score = 31.5 bits (68), Expect = 3.5
Identities = 22/96 (22%), Positives = 52/96 (54%), Gaps = 4/96 (4%)
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-EERSGTAQQKLLEAQQSADEN 123
E + LE+ E+++ E++ N+++Q++E+ L +E +Q L E +Q +
Sbjct: 1556 EVYRQSLEKLEEKM---ESQGIMKNKEIQELEQLLSSERQELDCLRKQYLSENEQWQQKL 1612
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 159
+ +E++ ++++ +QL+ +L+ ARL + D
Sbjct: 1613 TSVTLEMESKLAAEKKQTEQLSLELEVARLQLQGLD 1648
Score = 31.5 bits (68), Expect = 3.5
Identities = 21/107 (19%), Positives = 53/107 (49%), Gaps = 6/107 (5%)
Query: 40 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT-ATEAEVAALNRKVQQIEED 98
N+E++EL++ L+ ++L + + N+ ++K +T E+++AA ++ +Q+ +
Sbjct: 1577 NKEIQELEQLLSSERQELDCLRKQYLSENEQWQQKLTSVTLEMESKLAAEKKQTEQLSLE 1636
Query: 99 LEKSE---ERSGTAQQKLL--EAQQSADENNRMCKVLENRAQQDEER 140
LE + + + + LL + + + N C + + + ER
Sbjct: 1637 LEVARLQLQGLDLSSRSLLGIDTEDAIQGRNESCDISKEHTSETTER 1683
Score = 31.5 bits (68), Expect = 3.5
Identities = 41/208 (19%), Positives = 90/208 (43%), Gaps = 27/208 (12%)
Query: 31 DANLRAEKVNEEVRELQKKL--------AQVEEDLILNK--NKLEQANKDLEEKEKQLTA 80
D + + E + E++EL KL ++E + L K +L++ N DL EK + +
Sbjct: 1791 DRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSC 1850
Query: 81 TEAEVAALNRKVQQIEEDLE-----KSEERSGTAQQKLLEA--QQSADENNRMCKVLENR 133
E+ + + DLE S E G K+ ++ ++ D N + ++ +
Sbjct: 1851 DHQELLQRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVENELSRIRSEK 1910
Query: 134 AQQDEERMD-QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 192
A + E + + ++ + L + D ++ + + + +E+EL V ++ ++
Sbjct: 1911 ASIEHEALYLEADLEVVQTEKLCLEKDNENKQ--KVIVCLEEELSVV-------TSERNQ 1961
Query: 193 LEEELKVVGNSLKSLEVSEEKANQRVEE 220
L EL + +L+ EK ++ +E
Sbjct: 1962 LRGELDTMSKKTTALDQLSEKMKEKTQE 1989
Score = 30.3 bits (65), Expect = 8.0
Identities = 40/184 (21%), Positives = 84/184 (45%), Gaps = 18/184 (9%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ-----KKLAQVEE 55
M +K K + LE + + E + N + + ++ EV+E+ +L Q+E
Sbjct: 1156 MKVMKTKHECQNLESEPIRNSVKERESERNQCNFKPQ-MDLEVKEISLDSYNAQLVQLEA 1214
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE-----DLE-KSEERSGTA 109
L + KL+++ K+ E + +L ++ N + Q +E D E +EE+ +
Sbjct: 1215 MLRNKELKLQESEKEKECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYISG 1274
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQQDE-ERMDQLTNQLKEARLLAEDADGKSD--EVS 166
+L +Q D + C + + +E E++ ++ Q ++ L+ E D +S+ +
Sbjct: 1275 PHELSTSQN--DNAHLQCSLQTTMNKLNELEKICEIL-QAEKYELVTELNDSRSECITAT 1331
Query: 167 RKLA 170
RK+A
Sbjct: 1332 RKMA 1335
>U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protein
protein.
Length = 3210
Score = 60.1 bits (139), Expect = 9e-09
Identities = 49/276 (17%), Positives = 120/276 (43%), Gaps = 7/276 (2%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D +K +++ ++ E + A + +A ++ E + ++ + + L +E D++ +
Sbjct: 2428 DLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIR 2487
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ E +L++++++++ E ++ +Q+ E++ + +E+S TA + L Q
Sbjct: 2488 SEKEDLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEML---QTQLK 2544
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E N L N + + + L++Q++ L DE ++ +
Sbjct: 2545 ELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQ 2604
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXX 241
V+ G K+ + +EE+ + N ++ E K +Q E
Sbjct: 2605 EVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELE-- 2662
Query: 242 XXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDST 277
+ ++ LQ + L+D L + + YK+L +E++ T
Sbjct: 2663 --QKIQVLQSKNASLQDTLEVLQSSYKNLENELELT 2696
Score = 56.8 bits (131), Expect = 8e-08
Identities = 46/222 (20%), Positives = 101/222 (45%), Gaps = 14/222 (6%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-------QKKLAQVE 54
+ +K+K Q ++ + + E + ++ + ++ +V EL Q+KL +E
Sbjct: 2078 EKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLE 2137
Query: 55 ED---LILNK----NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 107
+D L L K N++ Q NK+ E K+ + +A ++ + + + + LE + G
Sbjct: 2138 KDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKG 2197
Query: 108 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 167
+L Q+ + R + L R + DE++ + +LKE + K + + R
Sbjct: 2198 EFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLER 2257
Query: 168 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 209
+L E+ E+ ++ A++ L+ +++ + SLK E+
Sbjct: 2258 ELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFEL 2299
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/218 (17%), Positives = 96/218 (44%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D++K K++ ++ E + + + A ++ E + ++ E+ + L E DL+ +
Sbjct: 2246 DSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 2305
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ E K ++EK+ QL+ + +++ +++ E+ + +E S TA + L + +
Sbjct: 2306 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELN 2365
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E + + E+ +D + + R E + + +K V +L+ +E
Sbjct: 2366 EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEH 2425
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
++ LE EL++ + + + E + VE
Sbjct: 2426 HADLLKGRVENLERELEIARTNQEHAALEAENSKGEVE 2463
Score = 54.0 bits (124), Expect = 6e-07
Identities = 56/278 (20%), Positives = 116/278 (41%), Gaps = 9/278 (3%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 65
+K + +EK+ ++K C + + ++ + + L++KL ++ EDL + E
Sbjct: 323 EKAKVELIEKEKVLNK---CRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAE 379
Query: 66 QANKDLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
A LE+K K+ + E++ R Q ++++ + + R Q+L +A+ +
Sbjct: 380 SARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKAR---LTQELQQAKNMHNVLQ 436
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
L + QQ E +++ +L A + + K +E+ R + ++ E + + +
Sbjct: 437 AELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSE 496
Query: 185 SGDAKISELEEELKVVGNSL-KSLEVSEE-KANQRVEEFXXXXXXXXXXXXXXXXXXXXX 242
++ LE ELK + L +S +EE KA +E
Sbjct: 497 QKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKL 556
Query: 243 XKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
V L+K+ D +D L + + L D++ T E
Sbjct: 557 KLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKE 594
Score = 54.0 bits (124), Expect = 6e-07
Identities = 52/282 (18%), Positives = 117/282 (41%), Gaps = 11/282 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED---L 57
+D + KK A+ + +K E + + EV+E + L + D L
Sbjct: 2063 LDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSEL 2122
Query: 58 ILNKNKLEQANKDLEEKEKQLTATEAE----VAALNRKVQQIEEDLEKSEERSGTAQQKL 113
+ +K L++ + LE+ + L+ T+ E +A LN++ + + ++ E + R + +
Sbjct: 2123 LKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEK 2182
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
L ++ + R +E + QL +++ R+ E + K ++ KL E
Sbjct: 2183 LNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERE 2242
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXX 233
E + +D+V++ + ++ EE ++V ++ + E ++EE
Sbjct: 2243 RENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLV 2302
Query: 234 XXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMD 275
K +++ Q ++ L+ L +KSL +E +
Sbjct: 2303 TLRSEKENLTKQIQEKQGQLSELDKLL----SSFKSLLEEKE 2340
Score = 46.8 bits (106), Expect = 9e-05
Identities = 41/223 (18%), Positives = 98/223 (43%), Gaps = 4/223 (1%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
++++ ++ EK N + + + LR EEV +L++ + ++ + ++
Sbjct: 2169 ESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADE 2228
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
K + L+E+E++ + + +V L R++Q EE+ E + ++ ++ + +
Sbjct: 2229 KKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIE 2288
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED-ELEVAE 180
E R KV E + LT Q++E + + D L E E+++ E
Sbjct: 2289 EMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKE 2348
Query: 181 D---RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ V+ ++ EL E + + + ++ +E+ + +EE
Sbjct: 2349 ESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEE 2391
Score = 46.4 bits (105), Expect = 1e-04
Identities = 45/223 (20%), Positives = 96/223 (43%), Gaps = 15/223 (6%)
Query: 65 EQANKDLEEKEKQLTATEA--EVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
EQ + E E +L A ++ A L +V +E LE ++ + Q++ E Q E
Sbjct: 803 EQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGE 862
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED---ELEVA 179
+ EN + ++ + + L ED + V+ L+ +E+ EL++
Sbjct: 863 ------IEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLL 916
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D+V++ A+I EL++ ++ +SLK L++ E + +E
Sbjct: 917 NDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQEN 976
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
T+K++ +++ + L + + + DE + + +EL+
Sbjct: 977 G----TLKEINASLNQEKMNLIQKSESFANYIDEREKSISELS 1015
Score = 44.0 bits (99), Expect = 6e-04
Identities = 46/258 (17%), Positives = 97/258 (37%), Gaps = 9/258 (3%)
Query: 16 DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKE 75
DN D+ +++ D ++ E ++ + +E DL + + + KD E K+
Sbjct: 1980 DNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQ 2039
Query: 76 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 135
K + E E++ + + Q+ +L+ T +K Q +++ + LE+
Sbjct: 2040 KVIVCLEEELSVVTSERNQLRGELD-------TMSKKTTALDQLSEKMKEKTQELESHQS 2092
Query: 136 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 195
+ + ++KE L + E+ + ++++L+ E ++ ELE
Sbjct: 2093 ECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELEN 2152
Query: 196 ELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDR 255
++ + + L E R+ E + Q+EV +
Sbjct: 2153 QIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQ 2212
Query: 256 LEDELGINKDRYKSLADE 273
L GI K R + ADE
Sbjct: 2213 L--RRGIEKLRVRIEADE 2228
Score = 41.5 bits (93), Expect = 0.003
Identities = 40/189 (21%), Positives = 81/189 (42%), Gaps = 3/189 (1%)
Query: 33 NLRAEKVNEEVRELQKKLAQVEEDLILNKNK-LEQANKDLEEKEKQLTATEAEVAALNRK 91
+L EK E++ ++ VE ++ N+ K L +A L ++ + ATE + +
Sbjct: 2334 SLLEEKEQAEIQIKEESKTAVE--MLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEE 2391
Query: 92 VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA 151
Q+ +EK R ++K L Q E+ +L+ R + E ++ + A
Sbjct: 2392 EHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHA 2451
Query: 152 RLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSE 211
L AE++ G+ + + K+ + L E V + ++ +L EL+ + LE+
Sbjct: 2452 ALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKEDLTNELQKEQERISELEIIN 2511
Query: 212 EKANQRVEE 220
++E
Sbjct: 2512 SSFENILQE 2520
Score = 39.9 bits (89), Expect = 0.010
Identities = 28/120 (23%), Positives = 57/120 (47%), Gaps = 3/120 (2%)
Query: 99 LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL---A 155
L+K +E G + E QQ + + + + + Q+ E + TN +E + L
Sbjct: 17 LQKIQELEGQLDKLKKEKQQRQFQLDSLEAAPQKQTQKVENEKTEGTNLKRENQRLMEIC 76
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
E + ++S +L E ++ E ++ SG +I +LE+ELK + L+ + + + A+
Sbjct: 77 ESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSAD 136
Score = 39.9 bits (89), Expect = 0.010
Identities = 33/127 (25%), Positives = 67/127 (52%), Gaps = 11/127 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D +KK+ Q + + D+ +A +Q + N + E N + RE Q+ L ++ E L
Sbjct: 27 LDKLKKEKQQRQFQLDSL--EAAPQKQTQKVENEKTEGTNLK-RENQR-LMEICESLEKT 82
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K K+ +L+ KE Q+ E ++ + ++++++E++L++ + +QQ A QSA
Sbjct: 83 KQKISH---ELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQ----AAQSA 135
Query: 121 DENNRMC 127
D + C
Sbjct: 136 DVSLNPC 142
Score = 37.5 bits (83), Expect = 0.053
Identities = 52/216 (24%), Positives = 102/216 (47%), Gaps = 38/216 (17%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE-------EKEK-------QLTATE 82
+++ ++ EL+ +L E+++ NK ++ LE EKEK +L T
Sbjct: 288 QELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTT 347
Query: 83 AE-------VAALNRKVQQIEEDL----EKSEERSGTAQQKLLEAQQS-ADENNRMCKVL 130
A+ AL +K++++ EDL + +E + +QK+ E ++ +E +R +
Sbjct: 348 AQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSF 407
Query: 131 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV-------AEDRV 183
+ Q+ + +LT +L++A+ + + D+++ +E+ LE AE
Sbjct: 408 QTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAF 467
Query: 184 KSGDAKISELE---EELKVVGNSLKSLEVSEEKANQ 216
++ K +EL EE+K N LKS SE+KA +
Sbjct: 468 QASQIKENELRRSMEEMKKENNLLKS--HSEQKARE 501
Score = 37.5 bits (83), Expect = 0.053
Identities = 51/184 (27%), Positives = 91/184 (49%), Gaps = 21/184 (11%)
Query: 6 KKMQAMKLEKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
++M+A ++ + D + QQ + +L EK+ V +L+K+ ++ L ++ +
Sbjct: 524 EEMKAKNTSQETMLRDLQEKINQQ--ENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHI 581
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEAQQSADE 122
EQ N L + EK+ ++A ++AL K ++ EE E+ S + +KLL +S E
Sbjct: 582 EQLNDKLSKTEKE---SKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKE 638
Query: 123 N-----NRM--C-KVLENRAQQDEERMDQL----TNQLKEARLLAEDADGKSDEV-SRKL 169
N N + C K + ++ + ER+ L N E R L D KS EV ++KL
Sbjct: 639 NLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKL 698
Query: 170 AFVE 173
A++E
Sbjct: 699 AYME 702
Score = 37.5 bits (83), Expect = 0.053
Identities = 40/176 (22%), Positives = 84/176 (47%), Gaps = 15/176 (8%)
Query: 41 EEVRELQKKLAQVEEDL-ILNKNKLEQANKDLEE-KEKQLTATEAEVAALNRKVQQIEED 98
++++EL + +++++ L ++K+++E+ K EE E QL EAE +K Q + D
Sbjct: 2758 DQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAE-----KKHQALLLD 2812
Query: 99 LEKSEE-RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 157
K E T ++KL ++ +L++ ++ L N LK + E+
Sbjct: 2813 TNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEE-------LNNSLKATTQILEE 2865
Query: 158 ADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
+ + + ++ E E A+ ++K +LEEE +++ L L+ ++EK
Sbjct: 2866 LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEK 2921
Score = 37.1 bits (82), Expect = 0.070
Identities = 41/183 (22%), Positives = 87/183 (47%), Gaps = 17/183 (9%)
Query: 34 LRAEKVNEE-VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 92
++AE++++ V E +++++++ED ++N + + LE KEK E+ LN KV
Sbjct: 868 MKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEK-------ELQLLNDKV 920
Query: 93 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
+ + ++++ ++ + + L E Q ++ + K + + ++ +++LT +E
Sbjct: 921 ETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELT---QENG 977
Query: 153 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
L E + E + E ++R KS ISEL ++ K L L+ EE
Sbjct: 978 TLKEINASLNQEKMNLIQKSESFANYIDEREKS----ISELSDQYK--QEKLILLQRCEE 1031
Query: 213 KAN 215
N
Sbjct: 1032 TGN 1034
Score = 36.7 bits (81), Expect = 0.092
Identities = 57/269 (21%), Positives = 104/269 (38%), Gaps = 25/269 (9%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
++K+Q MK + AM+ T ++ + E + ++ L+ E L L K +L
Sbjct: 2523 QEKVQ-MKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQL 2581
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
Q L+E + ++ V L ++V+ ++ LEK +E + ++ + +Q
Sbjct: 2582 LQG---LDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQ------ 2632
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
L ++ Q E Q E R L + + K + K A ++D LEV + K
Sbjct: 2633 -----LVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYK 2687
Query: 185 SGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXK 244
+ LE EL++ S EK N+ +
Sbjct: 2688 N-------LENELELTKMDKMSF---VEKVNKMTAKETELQREMHEMAQKTAELQEELSG 2737
Query: 245 TVKKLQKEVDRLEDELGINKDRYKSLADE 273
+L E+ L +E+ +KD+ K L E
Sbjct: 2738 EKNRLAGELQLLLEEIKSSKDQLKELTLE 2766
Score = 36.3 bits (80), Expect = 0.12
Identities = 45/215 (20%), Positives = 87/215 (40%), Gaps = 8/215 (3%)
Query: 13 LEKDNA-MDKADTC-EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKD 70
LEKDN K C E++ ++ E+ + KK +++ K K ++
Sbjct: 2031 LEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESH 2090
Query: 71 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
E + EAEV +Q + D+ + + Q+KL ++ + + L
Sbjct: 2091 QSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCEL 2150
Query: 131 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 190
EN+ Q + + L + + + ++D + VS+ L E R+ S ++
Sbjct: 2151 ENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEV 2210
Query: 191 SELE---EELKV--VGNSLKSLEVSEEKANQRVEE 220
+L E+L+V + K L ++ EK +R E
Sbjct: 2211 HQLRRGIEKLRVRIEADEKKQLHIA-EKLKERERE 2244
Score = 35.9 bits (79), Expect = 0.16
Identities = 33/139 (23%), Positives = 54/139 (38%)
Query: 82 EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
E EV +Q + D S + ++ L + + E LE R Q E+ M
Sbjct: 249 ELEVTPSRSTLQIGKRDANSSFFGNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEM 308
Query: 142 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 201
N+ +E +L E A + E + L DEL + K + LE++LK +
Sbjct: 309 KGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLT 368
Query: 202 NSLKSLEVSEEKANQRVEE 220
L + E A +E+
Sbjct: 369 EDLSCQRQNAESARCSLEQ 387
Score = 35.1 bits (77), Expect = 0.28
Identities = 47/276 (17%), Positives = 115/276 (41%), Gaps = 10/276 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ +++ K++K + ++K + + + ++ ++ ELQ++L+ + L
Sbjct: 2689 LENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQL 2748
Query: 64 LEQANKDLEEKEKQLTATEAEV-AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS--- 119
L + K +++ K+LT +E+ +L+ + E K E Q +L EA++
Sbjct: 2749 LLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQA 2808
Query: 120 --ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
D N + ++ ++ + + L++Q E LL + ++ + +E+ +
Sbjct: 2809 LLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKK 2868
Query: 178 VAEDRVKSGDAKISELEE---ELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXX 234
D +K + E E ++K++ S K LE +E + + +
Sbjct: 2869 TKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVM 2928
Query: 235 XXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSL 270
+ +K+L++ ++ E D+Y SL
Sbjct: 2929 DTKVDELTTE-IKELKETLEEKTKEADEYLDKYCSL 2963
Score = 34.7 bits (76), Expect = 0.37
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 8/134 (5%)
Query: 42 EVRELQKKLAQVEE-DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 100
E+ EL ++ ++E + LN+ K+ K E + E ++ L+ + +Q + L
Sbjct: 968 EIEELTQENGTLKEINASLNQEKMNLIQKS-ESFANYIDEREKSISELSDQYKQEKLILL 1026
Query: 101 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+ E +G A + L + ++A E N + L N E QLKEA A++
Sbjct: 1027 QRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEA--FAKE--- 1081
Query: 161 KSDEVSRKLAFVED 174
E KLAF E+
Sbjct: 1082 -HQEFLTKLAFAEE 1094
Score = 32.3 bits (70), Expect = 2.0
Identities = 53/238 (22%), Positives = 112/238 (47%), Gaps = 20/238 (8%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARD---ANLRAEK--VNEEVRELQKKLAQVEED 56
D +K K ++ +D+ +Q A AN+ E+ + E E + + Q ++
Sbjct: 765 DLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSERSECRLEADQSPKN 824
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE--RSGTAQ--QK 112
+ +N+++ LE +++ + + + L + +IEE+L K+E+ +S A+ Q+
Sbjct: 825 SAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQR 884
Query: 113 LLEAQQ--SADEN--NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
+ + Q+ SA +N LEN+ ++ + D++ + E + L + D + ++
Sbjct: 885 ISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSL-KE 943
Query: 169 LAFVEDELEVAEDRVKSGDAKISELE-EELKVVGNSLKSLEVS--EEKAN--QRVEEF 221
L + + L + E + S +++ E EEL +LK + S +EK N Q+ E F
Sbjct: 944 LQLLSETLSL-EKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESF 1000
Score = 31.9 bits (69), Expect = 2.6
Identities = 30/159 (18%), Positives = 71/159 (44%), Gaps = 3/159 (1%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
+K + M+ EK+N K + E + +++ + NE VR L+ + ++ N L
Sbjct: 627 EKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVL 686
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ + ++E ++ + + ++K Q +IE K+ + +G + + Q ++E
Sbjct: 687 DSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEI 746
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
+ ++ + E D L + K+A L+ + +S
Sbjct: 747 MDKDRCYQDLHAEYESLRDLLKS--KDASLVTNEDHQRS 783
Score = 31.5 bits (68), Expect = 3.5
Identities = 22/96 (22%), Positives = 52/96 (54%), Gaps = 4/96 (4%)
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-EERSGTAQQKLLEAQQSADEN 123
E + LE+ E+++ E++ N+++Q++E+ L +E +Q L E +Q +
Sbjct: 1653 EVYRQSLEKLEEKM---ESQGIMKNKEIQELEQLLSSERQELDCLRKQYLSENEQWQQKL 1709
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 159
+ +E++ ++++ +QL+ +L+ ARL + D
Sbjct: 1710 TSVTLEMESKLAAEKKQTEQLSLELEVARLQLQGLD 1745
Score = 31.5 bits (68), Expect = 3.5
Identities = 21/107 (19%), Positives = 53/107 (49%), Gaps = 6/107 (5%)
Query: 40 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT-ATEAEVAALNRKVQQIEED 98
N+E++EL++ L+ ++L + + N+ ++K +T E+++AA ++ +Q+ +
Sbjct: 1674 NKEIQELEQLLSSERQELDCLRKQYLSENEQWQQKLTSVTLEMESKLAAEKKQTEQLSLE 1733
Query: 99 LEKSE---ERSGTAQQKLL--EAQQSADENNRMCKVLENRAQQDEER 140
LE + + + + LL + + + N C + + + ER
Sbjct: 1734 LEVARLQLQGLDLSSRSLLGIDTEDAIQGRNESCDISKEHTSETTER 1780
Score = 31.5 bits (68), Expect = 3.5
Identities = 41/208 (19%), Positives = 90/208 (43%), Gaps = 27/208 (12%)
Query: 31 DANLRAEKVNEEVRELQKKL--------AQVEEDLILNK--NKLEQANKDLEEKEKQLTA 80
D + + E + E++EL KL ++E + L K +L++ N DL EK + +
Sbjct: 1888 DRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSC 1947
Query: 81 TEAEVAALNRKVQQIEEDLE-----KSEERSGTAQQKLLEA--QQSADENNRMCKVLENR 133
E+ + + DLE S E G K+ ++ ++ D N + ++ +
Sbjct: 1948 DHQELLQRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVENELSRIRSEK 2007
Query: 134 AQQDEERMD-QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 192
A + E + + ++ + L + D ++ + + + +E+EL V ++ ++
Sbjct: 2008 ASIEHEALYLEADLEVVQTEKLCLEKDNENKQ--KVIVCLEEELSVV-------TSERNQ 2058
Query: 193 LEEELKVVGNSLKSLEVSEEKANQRVEE 220
L EL + +L+ EK ++ +E
Sbjct: 2059 LRGELDTMSKKTTALDQLSEKMKEKTQE 2086
Score = 30.3 bits (65), Expect = 8.0
Identities = 40/184 (21%), Positives = 84/184 (45%), Gaps = 18/184 (9%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ-----KKLAQVEE 55
M +K K + LE + + E + N + + ++ EV+E+ +L Q+E
Sbjct: 1157 MKVMKTKHECQNLESEPIRNSVKERESERNQCNFKPQ-MDLEVKEISLDSYNAQLVQLEA 1215
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE-----DLE-KSEERSGTA 109
L + KL+++ K+ E + +L ++ N + Q +E D E +EE+ +
Sbjct: 1216 MLRNKELKLQESEKEKECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYISG 1275
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQQDE-ERMDQLTNQLKEARLLAEDADGKSD--EVS 166
+L +Q D + C + + +E E++ ++ Q ++ L+ E D +S+ +
Sbjct: 1276 PHELSTSQN--DNAHLQCSLQTTMNKLNELEKICEIL-QAEKYELVTELNDSRSECITAT 1332
Query: 167 RKLA 170
RK+A
Sbjct: 1333 RKMA 1336
>M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy chain
protein.
Length = 1937
Score = 60.1 bits (139), Expect = 9e-09
Identities = 44/208 (21%), Positives = 105/208 (50%), Gaps = 9/208 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ + ++ E + + ++ E++A+ A A + EE+++ Q A +E + KN
Sbjct: 1733 LENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MKKN- 1788
Query: 64 LEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
LEQ KDL E ++ L + ++ L +V+++E ++E ++R+ A + L + +
Sbjct: 1789 LEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHDR 1848
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
E + + ++ +D+L ++K + AE+A+ +S+ K ++ ELE
Sbjct: 1849 RVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEE 1908
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKS 206
AE+R ++++++L + + V + +
Sbjct: 1909 AEERADIAESQVNKLRVKSREVHTKISA 1936
Score = 58.0 bits (134), Expect = 3e-08
Identities = 59/277 (21%), Positives = 123/277 (44%), Gaps = 18/277 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++K+ +K+E D+ A+ + + ++V L+ K + E+ ++N
Sbjct: 1220 LEKEKSELKMETDDLSSNAEAISKAKGHLEKMCRSLEDQVSGLKTK--EEEQQRLINDLT 1277
Query: 64 LEQANKDLE--EKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQQKLLEAQ 117
++A E E +QL +A V+ L+R QQIEE + EE + A+ L A
Sbjct: 1278 AQRARLQTEAGEYSRQLDEQDALVSQLSRSKQASTQQIEELKHQLEEET-KAKNALAHAL 1336
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
QS+ + C +L + ++++E +L L +A +E A ++ + + E ELE
Sbjct: 1337 QSSRHD---CDLLREQYEEEQEGKAELQRALSKAN--SEVAQWRTKYETDAIQRTE-ELE 1390
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXX 237
A+ ++ ++ E EE ++ V SLE ++++ VE+
Sbjct: 1391 EAKKKLAQ---RLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDK 1447
Query: 238 XXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
K + + +++ + + EL ++ +SL+ E+
Sbjct: 1448 KQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTEL 1484
Score = 57.2 bits (132), Expect = 6e-08
Identities = 55/262 (20%), Positives = 114/262 (43%), Gaps = 20/262 (7%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE----QANK 69
E D+ D + CEQ ++ ++ E +EV E ++ ++ +L K KLE + K
Sbjct: 897 EADSLADAEERCEQLIKN-KIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKK 955
Query: 70 DLEEKE-------KQLTATEAEVAALNRKVQQIEEDLEK-SEERSG---TAQQKLLEAQQ 118
D+++ E KQ ATE +V L ++ ++E + K S+E+ T QQ L + Q
Sbjct: 956 DIDDLELTLAKVEKQKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQA 1015
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
D+ N +L + E+++D L L++ + L D + ++ L ++
Sbjct: 1016 EEDKVN----ILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMD 1071
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXX 238
E+ + D K+ + E E+ + + ++ + E + ++++E
Sbjct: 1072 MENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERAS 1131
Query: 239 XXXXXKTVKKLQKEVDRLEDEL 260
K L +E++ + + L
Sbjct: 1132 RAKAEKQRSDLSRELEEISERL 1153
Score = 52.0 bits (119), Expect = 2e-06
Identities = 52/261 (19%), Positives = 114/261 (43%), Gaps = 15/261 (5%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+++KM + EK++ + + DA R E++ + +L+ K+ +V E +
Sbjct: 876 LEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTE----RAEE 931
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK---LLEAQQSA 120
E+ N +L K+++L E E + L + + +E L K E++ + K L E
Sbjct: 932 EEEINAELTAKKRKL---EDECSELKKDIDDLELTLAKVEKQKHATENKVKNLTEEMAGL 988
Query: 121 DEN-NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
DE ++ K + + ++ +D L + + +L + +V +E E ++
Sbjct: 989 DETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLR 1048
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + AK +LE +LK+ S +E +++ ++++E+
Sbjct: 1049 MDLER---AK-RKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVE 1104
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
K +K+LQ ++ L +E+
Sbjct: 1105 IQLQKKIKELQARIEELGEEI 1125
Score = 50.8 bits (116), Expect = 5e-06
Identities = 47/285 (16%), Positives = 117/285 (41%), Gaps = 1/285 (0%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ ++ + A +++A+ E + ++ N E + + L
Sbjct: 1597 VETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKET 1656
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ L+ A + E+ ++QL E L +++++ LE++E A+Q+LL+A +
Sbjct: 1657 QLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERV 1716
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L N ++ E + QL ++++E + +A+ K+ + A + +EL+ +
Sbjct: 1717 QLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQ 1776
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + LE+ +K + + L E ++ + +++++
Sbjct: 1777 DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRN 1836
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K + V L + ++ L D +D A++ Y
Sbjct: 1837 AEAVKGLRKHDRRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSY 1881
Score = 48.0 bits (109), Expect = 4e-05
Identities = 28/165 (16%), Positives = 80/165 (48%)
Query: 49 KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 108
K A+ E+++ K + ++ +L + E + E ++ L ++ ++ ++ +
Sbjct: 844 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 903
Query: 109 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
A+++ + ++ + K + RA+++EE +LT + ++ + D++
Sbjct: 904 AEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELT 963
Query: 169 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
LA VE + E++VK+ +++ L+E + + K+L+ + ++
Sbjct: 964 LAKVEKQKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQ 1008
Score = 47.6 bits (108), Expect = 5e-05
Identities = 33/184 (17%), Positives = 88/184 (47%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K+ +V +LQ ++ +V ++ + K ++A D ++L + A L R + +E
Sbjct: 1731 KKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLE 1790
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R A+Q L+ ++ + + LE + +++R + L++
Sbjct: 1791 QTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHDRRV 1850
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + + ++D ++ + +VKS + E EE+ + + L+ E+A
Sbjct: 1851 KELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAE 1910
Query: 216 QRVE 219
+R +
Sbjct: 1911 ERAD 1914
Score = 45.6 bits (103), Expect = 2e-04
Identities = 46/209 (22%), Positives = 97/209 (46%), Gaps = 15/209 (7%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+Q+ D + + +++ EL+K QVE++ + LE+A LE +E ++ + E+
Sbjct: 1509 QQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLEL 1568
Query: 86 ----AALNRKVQQIEED---LEKSEERSGTAQQKLLEAQ-QSADENNRMCKVLENRAQQD 137
+ ++RK+ + +E+ L+++ R Q L+A+ +S ++ R+ K +E +
Sbjct: 1569 NQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEM 1628
Query: 138 EERMDQLTNQLKEARLLAEDADG-------KSDEVSRKLAFVEDELEVAEDRVKSGDAKI 190
E +++ E+ + G D+ R ++++L + E R A+I
Sbjct: 1629 EIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEI 1688
Query: 191 SELEEELKVVGNSLKSLEVSEEKANQRVE 219
EL L+ S K E A++RV+
Sbjct: 1689 EELWATLEQTERSRKIAEQELLDASERVQ 1717
Score = 44.4 bits (100), Expect = 5e-04
Identities = 36/177 (20%), Positives = 71/177 (40%), Gaps = 1/177 (0%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
QQ + + E+ + L L D L + + E+ + E ++ L+ +EVA
Sbjct: 1313 QQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVA 1372
Query: 87 ALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
K + + E+ EE Q+L EA++ + N C LE Q+ + ++ L
Sbjct: 1373 QWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLM 1432
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 202
++ + D K + L+ + + E + +++ + L EL V N
Sbjct: 1433 LDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKN 1489
Score = 43.6 bits (98), Expect = 8e-04
Identities = 53/232 (22%), Positives = 112/232 (48%), Gaps = 24/232 (10%)
Query: 1 MDAIKKKMQA-MKLEKDNAMDKADTCEQ--------QARDANLRAEKVNEEVRE--LQKK 49
++ K+K++ +KL +++ MD + +Q + +NL ++ +E+ E LQKK
Sbjct: 1051 LERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKK 1110
Query: 50 LAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 109
+ +++ ++E+ +++E + E + + L+R++++I E LE E T+
Sbjct: 1111 IKELQA-------RIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLE--EAGGATS 1161
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAEDADGKSDEVSRK 168
Q L ++ A E ++ + LE Q E + L + ++ L E D V +K
Sbjct: 1162 AQVELNKKREA-EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQID-NLQRVKQK 1219
Query: 169 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
L + EL++ D + S IS+ + L+ + SL+ +VS K + ++
Sbjct: 1220 LEKEKSELKMETDDLSSNAEAISKAKGHLEKMCRSLED-QVSGLKTKEEEQQ 1270
Score = 42.3 bits (95), Expect = 0.002
Identities = 34/190 (17%), Positives = 85/190 (44%), Gaps = 4/190 (2%)
Query: 23 DTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATE 82
+T +Q D +KVN + + + KL Q +DL + + ++ DLE +++L E
Sbjct: 1004 ETHQQTLDDLQAEEDKVNI-LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKL---E 1059
Query: 83 AEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 142
++ +E D ++ +E+ + ++ ++ + L+ + ++ + R++
Sbjct: 1060 GDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIE 1119
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 202
+L +++ R A+ + ++SR+L + + LE A + + E E + +
Sbjct: 1120 ELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRR 1179
Query: 203 SLKSLEVSEE 212
L+ + E
Sbjct: 1180 DLEEATLQHE 1189
Score = 41.1 bits (92), Expect = 0.004
Identities = 34/205 (16%), Positives = 94/205 (45%), Gaps = 7/205 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++ + ++ +K +K ++ + K+++E + LQ+ Q +DL
Sbjct: 957 IDDLELTLAKVEKQKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAE 1016
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
++K+ K + E+Q+ E + + +++ DLE+++ + + L AQ+S
Sbjct: 1017 EDKVNILTKAKTKLEQQVDDLEGSL----EQEKKLRMDLERAKRK---LEGDLKLAQEST 1069
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ + L+ + ++ E + L +++++ + + K E+ ++ + +E+E
Sbjct: 1070 MDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAER 1129
Query: 181 DRVKSGDAKISELEEELKVVGNSLK 205
+ + S+L EL+ + L+
Sbjct: 1130 ASRAKAEKQRSDLSRELEEISERLE 1154
Score = 38.7 bits (86), Expect = 0.023
Identities = 48/219 (21%), Positives = 97/219 (44%), Gaps = 23/219 (10%)
Query: 21 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILNKNKLE---QANKD-LEE 73
K+ E++ +K +E+ + + K ++EE L+ KN L+ Q+ D L +
Sbjct: 844 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 903
Query: 74 KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 133
E++ L K++++ E E+ EE + K + + E + LE
Sbjct: 904 AEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELT 963
Query: 134 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR----KLAFVE------DELEVAEDRV 183
+ E++ N++K L E+ G + +++ K A E D+L+ ED+V
Sbjct: 964 LAKVEKQKHATENKVKN---LTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKV 1020
Query: 184 KSGDAKISELEEELKVVGNSL---KSLEVSEEKANQRVE 219
++LE+++ + SL K L + E+A +++E
Sbjct: 1021 NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLE 1059
Score = 38.7 bits (86), Expect = 0.023
Identities = 51/259 (19%), Positives = 100/259 (38%), Gaps = 10/259 (3%)
Query: 9 QAMKLEKDNAMDKADTCEQQA--RDANLRAEKVNEEVRELQKKLAQVEEDL---ILNKN- 62
Q +LEK + + CE QA +A E ++ +Q +L QV+ ++ I K+
Sbjct: 1525 QIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE 1584
Query: 63 KLEQANKDLEEKEKQLTAT-EAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
+++Q ++ + + +T +AE+ + N R +++E DL + E + A + E+ +
Sbjct: 1585 EIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLR 1644
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
+ + K + + L QL A + +E+ L E ++
Sbjct: 1645 NYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKI 1704
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXX 238
AE + ++ L + + N+ K LE + VEE
Sbjct: 1705 AEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITD 1764
Query: 239 XXXXXKTVKKLQKEVDRLE 257
+ +KK Q LE
Sbjct: 1765 AAMMAEELKKEQDTSAHLE 1783
Score = 34.7 bits (76), Expect = 0.37
Identities = 51/223 (22%), Positives = 103/223 (46%), Gaps = 27/223 (12%)
Query: 14 EKDNAMDKADT-CEQQARD--ANLRAEK-----VNEEVRELQKKLAQVEEDLILNKNKLE 65
+K N + KA T EQQ D +L EK + R+L+ L +E + +N +
Sbjct: 1018 DKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQ 1077
Query: 66 QANKDLEEKEKQLT----ATEAEVAA---LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
Q ++ LE+KE +++ E E A L +K+++++ +E+ E + +A++
Sbjct: 1078 QLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEK 1137
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL--AFVEDEL 176
+ L ++ ER+++ L + + + ++ R L A ++ E
Sbjct: 1138 QRSD-------LSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEA 1190
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
VA R K D+ ++EL E++ + + LE +EK+ ++E
Sbjct: 1191 MVAALRKKHADS-MAELGEQIDNLQRVKQKLE--KEKSELKME 1230
Score = 30.3 bits (65), Expect = 8.0
Identities = 34/146 (23%), Positives = 68/146 (46%), Gaps = 18/146 (12%)
Query: 14 EKDNAMDKA-DTCEQQARDANLRAEKVNEEVRELQKKLAQVE---EDLILNKNKLEQANK 69
+K DK +Q+ + E +E R L +L +V+ E+ + L +A+K
Sbjct: 1447 KKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRAHK 1506
Query: 70 DLEEKEKQLTATEAE----VAALNRKVQQIEED-------LEKSEERSGTAQQKLLEAQQ 118
+L+++ LT AE + L + +Q+E++ LE++E + K+L Q
Sbjct: 1507 NLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQL 1566
Query: 119 SADENNRMCKVLENRAQQDEERMDQL 144
E N++ ++ + + +E +DQL
Sbjct: 1567 ---ELNQVKSEVDRKIAEKDEEIDQL 1589
>BC101520-1|AAI01521.1| 1194|Homo sapiens protein tyrosine
phosphatase, receptor type, f polypeptide (PTPRF),
interacting protein.
Length = 1194
Score = 60.1 bits (139), Expect = 9e-09
Identities = 61/270 (22%), Positives = 119/270 (44%), Gaps = 17/270 (6%)
Query: 31 DANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR 90
D+N R ++ E + + ++ Q+ E L + ++ Q ++L ++L E + L R
Sbjct: 230 DSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQR 289
Query: 91 KVQQIEEDLEKSEERSGTAQQKLLEAQQSA----DENNRMCKVL---ENRAQQDEERMDQ 143
+++ E EER T +++ L AQ+ A D N+++ L E+ +Q EE+ Q
Sbjct: 290 DLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQ 349
Query: 144 LTNQLKEARLLAEDADGKSD---EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 200
L L +A+ + K++ E+ +LA L AE+R + + ++ +LE +L+
Sbjct: 350 LAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEK 409
Query: 201 GNSL---KSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVK-KLQKEV--- 253
L + E + N+R+ E K L +E+
Sbjct: 410 NQELQRARQREKMNDDHNKRLSETVDKLLSESNERLQLHLKERMGALEEKNSLSEEIANM 469
Query: 254 DRLEDELGINKDRYKSLADEMDSTFAELAG 283
+L+DEL +NK++ + + M +L G
Sbjct: 470 KKLQDELLLNKEQLLAEMERMQMEIDQLRG 499
Score = 35.1 bits (77), Expect = 0.28
Identities = 56/277 (20%), Positives = 109/277 (39%), Gaps = 37/277 (13%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILN-------KNKLEQANKDLEEKEKQ-----LTATEAE 84
EKV E +R +++A +EE+L L+ + +L + LEE K L
Sbjct: 168 EKVRERLRMALERVAVLEEELELSNQETLNLREQLSRRRSGLEEPGKDGDGQTLANGLGP 227
Query: 85 VAALNRKVQQIEEDLEKS---------------------EERSGTAQQKLLEAQQSADEN 123
NR+ ++EE LE+ EE GTA ++L +A+++ +
Sbjct: 228 GGDSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKL 287
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
R K + + EER+ L + A+ A +D++ +LA E +E++
Sbjct: 288 QRDLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKS 347
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXX 243
+ + + +++L+ ++L E + QRV
Sbjct: 348 RQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRV----AALNKAEERHGNFEERLRQLE 403
Query: 244 KTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
+++ +E+ R +N D K L++ +D +E
Sbjct: 404 AQLEEKNQELQRARQREKMNDDHNKRLSETVDKLLSE 440
Score = 31.5 bits (68), Expect = 3.5
Identities = 41/223 (18%), Positives = 95/223 (42%), Gaps = 35/223 (15%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M +++++ E A + ++ ++A + E + E + L+K+ + +
Sbjct: 263 MSQLEEELGTAHRELGKAEEANSKLQRDLKEALAQREDMEERITTLEKRYLSAQREATSL 322
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEED--------------- 98
+ ++ +L KE +E + L +K+QQ +
Sbjct: 323 HDANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRV 382
Query: 99 --LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA--RLL 154
L K+EER G +++L + + +E N+ + RA+Q E+ D +L E +LL
Sbjct: 383 AALNKAEERHGNFEERLRQLEAQLEEKNQELQ----RARQREKMNDDHNKRLSETVDKLL 438
Query: 155 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 197
+E + + ++ +E++ ++E+ A + +L++EL
Sbjct: 439 SESNERLQLHLKERMGALEEKNSLSEE-----IANMKKLQDEL 476
>BC101518-1|AAI01519.1| 1194|Homo sapiens protein tyrosine
phosphatase, receptor type, f polypeptide (PTPRF),
interacting protein.
Length = 1194
Score = 60.1 bits (139), Expect = 9e-09
Identities = 61/270 (22%), Positives = 119/270 (44%), Gaps = 17/270 (6%)
Query: 31 DANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR 90
D+N R ++ E + + ++ Q+ E L + ++ Q ++L ++L E + L R
Sbjct: 230 DSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQR 289
Query: 91 KVQQIEEDLEKSEERSGTAQQKLLEAQQSA----DENNRMCKVL---ENRAQQDEERMDQ 143
+++ E EER T +++ L AQ+ A D N+++ L E+ +Q EE+ Q
Sbjct: 290 DLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQ 349
Query: 144 LTNQLKEARLLAEDADGKSD---EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 200
L L +A+ + K++ E+ +LA L AE+R + + ++ +LE +L+
Sbjct: 350 LAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEK 409
Query: 201 GNSL---KSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVK-KLQKEV--- 253
L + E + N+R+ E K L +E+
Sbjct: 410 NQELQRARQREKMNDDHNKRLSETVDKLLSESNERLQLHLKERMGALEEKNSLSEEIANM 469
Query: 254 DRLEDELGINKDRYKSLADEMDSTFAELAG 283
+L+DEL +NK++ + + M +L G
Sbjct: 470 KKLQDELLLNKEQLLAEMERMQMEIDQLRG 499
Score = 35.1 bits (77), Expect = 0.28
Identities = 56/277 (20%), Positives = 109/277 (39%), Gaps = 37/277 (13%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILN-------KNKLEQANKDLEEKEKQ-----LTATEAE 84
EKV E +R +++A +EE+L L+ + +L + LEE K L
Sbjct: 168 EKVRERLRMALERVAVLEEELELSNQETLNLREQLSRRRSGLEEPGKDGDGQTLANGLGP 227
Query: 85 VAALNRKVQQIEEDLEKS---------------------EERSGTAQQKLLEAQQSADEN 123
NR+ ++EE LE+ EE GTA ++L +A+++ +
Sbjct: 228 GGDSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKL 287
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
R K + + EER+ L + A+ A +D++ +LA E +E++
Sbjct: 288 QRDLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKS 347
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXX 243
+ + + +++L+ ++L E + QRV
Sbjct: 348 RQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRV----AALNKAEERHGNFEERLRQLE 403
Query: 244 KTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
+++ +E+ R +N D K L++ +D +E
Sbjct: 404 AQLEEKNQELQRARQREKMNDDHNKRLSETVDKLLSE 440
Score = 31.5 bits (68), Expect = 3.5
Identities = 41/223 (18%), Positives = 95/223 (42%), Gaps = 35/223 (15%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M +++++ E A + ++ ++A + E + E + L+K+ + +
Sbjct: 263 MSQLEEELGTAHRELGKAEEANSKLQRDLKEALAQREDMEERITTLEKRYLSAQREATSL 322
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEED--------------- 98
+ ++ +L KE +E + L +K+QQ +
Sbjct: 323 HDANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRV 382
Query: 99 --LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA--RLL 154
L K+EER G +++L + + +E N+ + RA+Q E+ D +L E +LL
Sbjct: 383 AALNKAEERHGNFEERLRQLEAQLEEKNQELQ----RARQREKMNDDHNKRLSETVDKLL 438
Query: 155 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 197
+E + + ++ +E++ ++E+ A + +L++EL
Sbjct: 439 SESNERLQLHLKERMGALEEKNSLSEE-----IANMKKLQDEL 476
>AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical
rhabdomyosarcoma antigen MU-RMS-40.3 protein.
Length = 941
Score = 60.1 bits (139), Expect = 9e-09
Identities = 50/217 (23%), Positives = 110/217 (50%), Gaps = 13/217 (5%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKK++ ++ E ++A A E++A+ A A + EE+++ Q A +E +
Sbjct: 729 KKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 785
Query: 61 KNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
KN LEQ KDL E ++ L + ++ L +++++E +LE ++++ + + L +
Sbjct: 786 KN-LEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRK 844
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
++ E + + ++ +D+L ++K + AE+AD +++ K + E
Sbjct: 845 YERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHE 904
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
LE AE+R ++++++L + + +S + SEE
Sbjct: 905 LEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESEE 941
Score = 56.8 bits (131), Expect = 8e-08
Identities = 49/285 (17%), Positives = 120/285 (42%), Gaps = 1/285 (0%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ ++ + A ++ A+ E + ++ N + E K L V+ L
Sbjct: 596 VETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDT 655
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ L+ A + E+ ++QL E L +V+++ LE++E A+Q+LL++ +
Sbjct: 656 QLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERV 715
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L + ++ E + QL +++++A A +A+ K+ + A + +EL+ +
Sbjct: 716 QLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQ 775
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + LE+ +K + + L E ++ + +++++
Sbjct: 776 DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKN 835
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K ++ V L + ++ L D +D ++ Y
Sbjct: 836 TESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSY 880
Score = 53.6 bits (123), Expect = 8e-07
Identities = 45/261 (17%), Positives = 115/261 (44%), Gaps = 8/261 (3%)
Query: 5 KKKMQAMKLEKDNAMDKADT-CEQQARDANLRAEKVNEEVRELQKKLAQVE---EDLILN 60
+ K + +++ +++A Q+ +D+ + E VN + L+K +++ EDL+++
Sbjct: 374 RTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVD 433
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ L++K++ AE K ++ + +LE S + S + +L + + +
Sbjct: 434 VERANSLAAALDKKQRNFDKVLAE---WKTKCEESQAELEASLKESRSLSTELFKLKNAY 490
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+E + ++ + E+ + LT Q+ E + + ++ + A ++ LE AE
Sbjct: 491 EEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAE 550
Query: 181 DRVKSGDAKISELEEELKVVGNSL-KSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
++ +AKI ++ EL V + + + + +E+ Q +
Sbjct: 551 AALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSR 610
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
+ KK++ +++ +E +L
Sbjct: 611 NEAIRLKKKMEGDLNEIEIQL 631
Score = 53.2 bits (122), Expect = 1e-06
Identities = 55/288 (19%), Positives = 124/288 (43%), Gaps = 22/288 (7%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D + M+++ K N T E Q +A + E++ + EL + ++++ +
Sbjct: 230 IDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEA--- 286
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ ++ LEEKE ++ A ++ ++++ LE+ + A+ L A QS+
Sbjct: 287 ----GELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENK----AKNALAHALQSS 338
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRKLAFV 172
+ C +L + ++++E +L L +A +A+ DA +++E+ +
Sbjct: 339 RHD---CDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 395
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXX 232
L+ +E++V++ +AK + LE+ + + ++ L V E+AN
Sbjct: 396 AQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVL 455
Query: 233 XXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
++ KE L EL K+ Y+ D++++ E
Sbjct: 456 AEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRE 503
Score = 45.6 bits (103), Expect = 2e-04
Identities = 30/153 (19%), Positives = 74/153 (48%), Gaps = 3/153 (1%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
QQA D +L+AE+ ++V L K +++E+ + ++ LEQ K + E+ E ++
Sbjct: 6 QQALD-DLQAEE--DKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLK 62
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+ +E D ++ +ER + + Q ++ + + + ++ + R+++L
Sbjct: 63 LAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEE 122
Query: 147 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+++ R + + + +R+L + + LE A
Sbjct: 123 EIEAERATRAKTEKQRSDYARELEELSERLEEA 155
Score = 44.8 bits (101), Expect = 3e-04
Identities = 44/209 (21%), Positives = 98/209 (46%), Gaps = 15/209 (7%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDL---EEKEKQLTATE 82
EQ+ D+N R + ++ + L ++E DL+ ++++E A++D EEK K+
Sbjct: 705 EQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDA 764
Query: 83 AEVAALNRKVQQIEEDLEKS----EERSGTAQQKLLEAQQSADENNR-MCKVLENRAQQ- 136
A +A +K Q LE+ E+ Q +L EA+Q A + + + LE R ++
Sbjct: 765 AMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIREL 824
Query: 137 ------DEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 190
++++ + L++ ++ +S+E + + ++D ++ + +VKS +
Sbjct: 825 EFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQA 884
Query: 191 SELEEELKVVGNSLKSLEVSEEKANQRVE 219
E +E+ + + E+A +R +
Sbjct: 885 EEADEQANAHLTKFRKAQHELEEAEERAD 913
Score = 41.9 bits (94), Expect = 0.002
Identities = 46/222 (20%), Positives = 105/222 (47%), Gaps = 13/222 (5%)
Query: 5 KKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
K+K++ +KL +++ +D E + + R +K + E +LQ K+ + + + K
Sbjct: 54 KRKLEGDLKLAQESILD----LENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKK 109
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQQKLLEAQQS 119
+++ +EE E+++ A A A ++ +++EE E+ EE G ++ ++
Sbjct: 110 IKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKR 169
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVEDELEV 178
E ++ + LE Q E + L + ++ L E D V +KL + E ++
Sbjct: 170 EAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQID-NLQRVKQKLEKEKSEFKL 228
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA-NQRVE 219
D + S +S+ + L+ + +L+ ++SE + N+ ++
Sbjct: 229 EIDDLSSSMESVSKSKANLEKICRTLED-QLSEARGKNEEIQ 269
Score = 41.9 bits (94), Expect = 0.002
Identities = 41/198 (20%), Positives = 95/198 (47%), Gaps = 12/198 (6%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+++ ++ R E++ EE+ + A+ E+ +LE+ ++ LEE +T+T+ E
Sbjct: 107 QKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGG-VTSTQIE- 164
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEA---QQSADENNRMCKVLENRAQQDEERMD 142
LN+K + L + E + T Q + + A ++ AD + + ++N Q+ +++++
Sbjct: 165 --LNKKREAEFLKLRRDLEEA-TLQHEAMVATLRKKHADSVAELGEQIDN-LQRVKQKLE 220
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGN 202
+ + E +L +D + VS+ A +E ED++ K E++ L +
Sbjct: 221 K---EKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTT 277
Query: 203 SLKSLEVSEEKANQRVEE 220
L+ + ++++EE
Sbjct: 278 QKSRLQTEAGELSRQLEE 295
Score = 41.1 bits (92), Expect = 0.004
Identities = 46/248 (18%), Positives = 111/248 (44%), Gaps = 18/248 (7%)
Query: 46 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 105
LQ+ Q +DL ++K+ NK + E+Q+ E+ + + +E + K E
Sbjct: 1 LQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGD 60
Query: 106 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 165
AQ+ +L+ EN++ + L+ R ++ + QL +++++ + L K E+
Sbjct: 61 LKLAQESILDL-----ENDK--QQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKEL 113
Query: 166 SRKLAFVEDELEVAE------DRVKSGDAK-ISELEEELKVVGN-SLKSLEVSEEKANQR 217
++ +E+E+E ++ +S A+ + EL E L+ G + +E+++++ +
Sbjct: 114 QARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEF 173
Query: 218 VEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVD---RLEDELGINKDRYKSLADEM 274
++ +V +L +++D R++ +L K +K D++
Sbjct: 174 LKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDL 233
Query: 275 DSTFAELA 282
S+ ++
Sbjct: 234 SSSMESVS 241
>AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 60.1 bits (139), Expect = 9e-09
Identities = 49/276 (17%), Positives = 120/276 (43%), Gaps = 7/276 (2%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D +K +++ ++ E + A + +A ++ E + ++ + + L +E D++ +
Sbjct: 2332 DLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIR 2391
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ E +L++++++++ E ++ +Q+ E++ + +E+S TA + L Q
Sbjct: 2392 SEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEML---QTQLK 2448
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E N L N + + + L++Q++ L DE ++ +
Sbjct: 2449 ELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQ 2508
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXX 241
V+ G K+ + +EE+ + N ++ E K +Q E
Sbjct: 2509 EVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELE-- 2566
Query: 242 XXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDST 277
+ ++ LQ + L+D L + + YK+L +E++ T
Sbjct: 2567 --QKIQVLQSKNASLQDTLEVLQSSYKNLENELELT 2600
Score = 56.8 bits (131), Expect = 8e-08
Identities = 46/222 (20%), Positives = 101/222 (45%), Gaps = 14/222 (6%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-------QKKLAQVE 54
+ +K+K Q ++ + + E + ++ + ++ +V EL Q+KL +E
Sbjct: 1982 EKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLE 2041
Query: 55 ED---LILNK----NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 107
+D L L K N++ Q NK+ E K+ + +A ++ + + + + LE + G
Sbjct: 2042 KDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKG 2101
Query: 108 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 167
+L Q+ + R + L R + DE++ + +LKE + K + + R
Sbjct: 2102 EFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLER 2161
Query: 168 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 209
+L E+ E+ ++ A++ L+ +++ + SLK E+
Sbjct: 2162 ELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFEL 2203
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/218 (17%), Positives = 96/218 (44%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D++K K++ ++ E + + + A ++ E + ++ E+ + L E DL+ +
Sbjct: 2150 DSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 2209
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ E K ++EK+ QL+ + +++ +++ E+ + +E S TA + L + +
Sbjct: 2210 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELN 2269
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E + + E+ +D + + R E + + +K V +L+ +E
Sbjct: 2270 EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEH 2329
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
++ LE EL++ + + + E + VE
Sbjct: 2330 HADLLKGRVENLERELEIARTNQEHAALEAENSKGEVE 2367
Score = 54.0 bits (124), Expect = 6e-07
Identities = 56/278 (20%), Positives = 116/278 (41%), Gaps = 9/278 (3%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 65
+K + +EK+ ++K C + + ++ + + L++KL ++ EDL + E
Sbjct: 323 EKAKVELIEKEKVLNK---CRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAE 379
Query: 66 QANKDLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
A LE+K K+ + E++ R Q ++++ + + R Q+L +A+ +
Sbjct: 380 SARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKAR---LTQELQQAKNMHNVLQ 436
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
L + QQ E +++ +L A + + K +E+ R + ++ E + + +
Sbjct: 437 AELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSE 496
Query: 185 SGDAKISELEEELKVVGNSL-KSLEVSEE-KANQRVEEFXXXXXXXXXXXXXXXXXXXXX 242
++ LE ELK + L +S +EE KA +E
Sbjct: 497 QKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKL 556
Query: 243 XKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
V L+K+ D +D L + + L D++ T E
Sbjct: 557 KLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKE 594
Score = 54.0 bits (124), Expect = 6e-07
Identities = 52/282 (18%), Positives = 117/282 (41%), Gaps = 11/282 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED---L 57
+D + KK A+ + +K E + + EV+E + L + D L
Sbjct: 1967 LDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSEL 2026
Query: 58 ILNKNKLEQANKDLEEKEKQLTATEAE----VAALNRKVQQIEEDLEKSEERSGTAQQKL 113
+ +K L++ + LE+ + L+ T+ E +A LN++ + + ++ E + R + +
Sbjct: 2027 LKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEK 2086
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
L ++ + R +E + QL +++ R+ E + K ++ KL E
Sbjct: 2087 LNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERE 2146
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXX 233
E + +D+V++ + ++ EE ++V ++ + E ++EE
Sbjct: 2147 RENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLV 2206
Query: 234 XXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMD 275
K +++ Q ++ L+ L +KSL +E +
Sbjct: 2207 TLRSEKENLTKQIQEKQGQLSELDKLL----SSFKSLLEEKE 2244
Score = 46.8 bits (106), Expect = 9e-05
Identities = 41/223 (18%), Positives = 98/223 (43%), Gaps = 4/223 (1%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
++++ ++ EK N + + + LR EEV +L++ + ++ + ++
Sbjct: 2073 ESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADE 2132
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
K + L+E+E++ + + +V L R++Q EE+ E + ++ ++ + +
Sbjct: 2133 KKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIE 2192
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED-ELEVAE 180
E R KV E + LT Q++E + + D L E E+++ E
Sbjct: 2193 EMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKE 2252
Query: 181 D---RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ V+ ++ EL E + + + ++ +E+ + +EE
Sbjct: 2253 ESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEE 2295
Score = 46.4 bits (105), Expect = 1e-04
Identities = 45/223 (20%), Positives = 96/223 (43%), Gaps = 15/223 (6%)
Query: 65 EQANKDLEEKEKQLTATEA--EVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
EQ + E E +L A ++ A L +V +E LE ++ + Q++ E Q E
Sbjct: 803 EQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGE 862
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED---ELEVA 179
+ EN + ++ + + L ED + V+ L+ +E+ EL++
Sbjct: 863 ------IEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLL 916
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D+V++ A+I EL++ ++ +SLK L++ E + +E
Sbjct: 917 NDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQEN 976
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
T+K++ +++ + L + + + DE + + +EL+
Sbjct: 977 G----TLKEINASLNQEKMNLIQKSESFANYIDEREKSISELS 1015
Score = 44.0 bits (99), Expect = 6e-04
Identities = 46/258 (17%), Positives = 97/258 (37%), Gaps = 9/258 (3%)
Query: 16 DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKE 75
DN D+ +++ D ++ E ++ + +E DL + + + KD E K+
Sbjct: 1884 DNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQ 1943
Query: 76 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 135
K + E E++ + + Q+ +L+ T +K Q +++ + LE+
Sbjct: 1944 KVIVCLEEELSVVTSERNQLRGELD-------TMSKKTTALDQLSEKMKEKTQELESHQS 1996
Query: 136 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 195
+ + ++KE L + E+ + ++++L+ E ++ ELE
Sbjct: 1997 ECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELEN 2056
Query: 196 ELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDR 255
++ + + L E R+ E + Q+EV +
Sbjct: 2057 QIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQ 2116
Query: 256 LEDELGINKDRYKSLADE 273
L GI K R + ADE
Sbjct: 2117 L--RRGIEKLRVRIEADE 2132
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/120 (24%), Positives = 58/120 (48%), Gaps = 3/120 (2%)
Query: 99 LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL---A 155
L+K +E G + E QQ + + + L+ + Q+ E + TN +E + L
Sbjct: 17 LQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEIC 76
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
E + ++S +L E ++ E ++ SG +I +LE+ELK + L+ + + + A+
Sbjct: 77 ESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSAD 136
Score = 40.7 bits (91), Expect = 0.006
Identities = 33/127 (25%), Positives = 68/127 (53%), Gaps = 11/127 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D +KK+ Q + + D+ +A +Q+ + N + E N + RE Q+ L ++ E L
Sbjct: 27 LDKLKKEKQQRQFQLDSL--EAALQKQKQKVENEKTEGTNLK-RENQR-LMEICESLEKT 82
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K K+ +L+ KE Q+ E ++ + ++++++E++L++ + +QQ A QSA
Sbjct: 83 KQKISH---ELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQ----AAQSA 135
Query: 121 DENNRMC 127
D + C
Sbjct: 136 DVSLNPC 142
Score = 40.7 bits (91), Expect = 0.006
Identities = 40/189 (21%), Positives = 80/189 (42%), Gaps = 3/189 (1%)
Query: 33 NLRAEKVNEEVRELQKKLAQVEEDLILNKNK-LEQANKDLEEKEKQLTATEAEVAALNRK 91
+L EK E++ ++ VE ++ N+ K L +A L ++ + ATE + +
Sbjct: 2238 SLLEEKEQAEIQIKEESKTAVE--MLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEE 2295
Query: 92 VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA 151
Q+ +EK R ++K L Q E+ +L+ R + E ++ + A
Sbjct: 2296 EHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHA 2355
Query: 152 RLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSE 211
L AE++ G+ + + K+ + L E V + ++ L EL+ + LE+
Sbjct: 2356 ALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIIN 2415
Query: 212 EKANQRVEE 220
++E
Sbjct: 2416 SSFENILQE 2424
Score = 37.5 bits (83), Expect = 0.053
Identities = 52/216 (24%), Positives = 102/216 (47%), Gaps = 38/216 (17%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE-------EKEK-------QLTATE 82
+++ ++ EL+ +L E+++ NK ++ LE EKEK +L T
Sbjct: 288 QELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTT 347
Query: 83 AE-------VAALNRKVQQIEEDL----EKSEERSGTAQQKLLEAQQS-ADENNRMCKVL 130
A+ AL +K++++ EDL + +E + +QK+ E ++ +E +R +
Sbjct: 348 AQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSF 407
Query: 131 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV-------AEDRV 183
+ Q+ + +LT +L++A+ + + D+++ +E+ LE AE
Sbjct: 408 QTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAF 467
Query: 184 KSGDAKISELE---EELKVVGNSLKSLEVSEEKANQ 216
++ K +EL EE+K N LKS SE+KA +
Sbjct: 468 QASQIKENELRRSMEEMKKENNLLKS--HSEQKARE 501
Score = 37.5 bits (83), Expect = 0.053
Identities = 51/184 (27%), Positives = 91/184 (49%), Gaps = 21/184 (11%)
Query: 6 KKMQAMKLEKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
++M+A ++ + D + QQ + +L EK+ V +L+K+ ++ L ++ +
Sbjct: 524 EEMKAKNTSQETMLRDLQEKINQQ--ENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHI 581
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEAQQSADE 122
EQ N L + EK+ ++A ++AL K ++ EE E+ S + +KLL +S E
Sbjct: 582 EQLNDKLSKTEKE---SKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKE 638
Query: 123 N-----NRM--C-KVLENRAQQDEERMDQL----TNQLKEARLLAEDADGKSDEV-SRKL 169
N N + C K + ++ + ER+ L N E R L D KS EV ++KL
Sbjct: 639 NLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKL 698
Query: 170 AFVE 173
A++E
Sbjct: 699 AYME 702
Score = 37.5 bits (83), Expect = 0.053
Identities = 40/176 (22%), Positives = 84/176 (47%), Gaps = 15/176 (8%)
Query: 41 EEVRELQKKLAQVEEDL-ILNKNKLEQANKDLEE-KEKQLTATEAEVAALNRKVQQIEED 98
++++EL + +++++ L ++K+++E+ K EE E QL EAE +K Q + D
Sbjct: 2662 DQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAE-----KKHQALLLD 2716
Query: 99 LEKSEE-RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 157
K E T ++KL ++ +L++ ++ L N LK + E+
Sbjct: 2717 TNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEE-------LNNSLKATTQILEE 2769
Query: 158 ADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
+ + + ++ E E A+ ++K +LEEE +++ L L+ ++EK
Sbjct: 2770 LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEK 2825
Score = 37.1 bits (82), Expect = 0.070
Identities = 41/183 (22%), Positives = 87/183 (47%), Gaps = 17/183 (9%)
Query: 34 LRAEKVNEE-VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 92
++AE++++ V E +++++++ED ++N + + LE KEK E+ LN KV
Sbjct: 868 MKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEK-------ELQLLNDKV 920
Query: 93 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
+ + ++++ ++ + + L E Q ++ + K + + ++ +++LT +E
Sbjct: 921 ETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELT---QENG 977
Query: 153 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
L E + E + E ++R KS ISEL ++ K L L+ EE
Sbjct: 978 TLKEINASLNQEKMNLIQKSESFANYIDEREKS----ISELSDQYK--QEKLILLQRCEE 1031
Query: 213 KAN 215
N
Sbjct: 1032 TGN 1034
Score = 36.7 bits (81), Expect = 0.092
Identities = 57/269 (21%), Positives = 104/269 (38%), Gaps = 25/269 (9%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
++K+Q MK + AM+ T ++ + E + ++ L+ E L L K +L
Sbjct: 2427 QEKVQ-MKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQL 2485
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
Q L+E + ++ V L ++V+ ++ LEK +E + ++ + +Q
Sbjct: 2486 LQG---LDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQ------ 2536
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
L ++ Q E Q E R L + + K + K A ++D LEV + K
Sbjct: 2537 -----LVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYK 2591
Query: 185 SGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXK 244
+ LE EL++ S EK N+ +
Sbjct: 2592 N-------LENELELTKMDKMSF---VEKVNKMTAKETELQREMHEMAQKTAELQEELSG 2641
Query: 245 TVKKLQKEVDRLEDELGINKDRYKSLADE 273
+L E+ L +E+ +KD+ K L E
Sbjct: 2642 EKNRLAGELQLLLEEIKSSKDQLKELTLE 2670
Score = 36.3 bits (80), Expect = 0.12
Identities = 45/215 (20%), Positives = 87/215 (40%), Gaps = 8/215 (3%)
Query: 13 LEKDNA-MDKADTC-EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKD 70
LEKDN K C E++ ++ E+ + KK +++ K K ++
Sbjct: 1935 LEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESH 1994
Query: 71 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
E + EAEV +Q + D+ + + Q+KL ++ + + L
Sbjct: 1995 QSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCEL 2054
Query: 131 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 190
EN+ Q + + L + + + ++D + VS+ L E R+ S ++
Sbjct: 2055 ENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEV 2114
Query: 191 SELE---EELKV--VGNSLKSLEVSEEKANQRVEE 220
+L E+L+V + K L ++ EK +R E
Sbjct: 2115 HQLRRGIEKLRVRIEADEKKQLHIA-EKLKERERE 2148
Score = 35.9 bits (79), Expect = 0.16
Identities = 33/139 (23%), Positives = 54/139 (38%)
Query: 82 EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
E EV +Q + D S + ++ L + + E LE R Q E+ M
Sbjct: 249 EQEVTPSRSTLQIGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEM 308
Query: 142 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 201
N+ +E +L E A + E + L DEL + K + LE++LK +
Sbjct: 309 KGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLT 368
Query: 202 NSLKSLEVSEEKANQRVEE 220
L + E A +E+
Sbjct: 369 EDLSCQRQNAESARCSLEQ 387
Score = 35.1 bits (77), Expect = 0.28
Identities = 47/276 (17%), Positives = 115/276 (41%), Gaps = 10/276 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ +++ K++K + ++K + + + ++ ++ ELQ++L+ + L
Sbjct: 2593 LENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQL 2652
Query: 64 LEQANKDLEEKEKQLTATEAEV-AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS--- 119
L + K +++ K+LT +E+ +L+ + E K E Q +L EA++
Sbjct: 2653 LLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQA 2712
Query: 120 --ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
D N + ++ ++ + + L++Q E LL + ++ + +E+ +
Sbjct: 2713 LLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKK 2772
Query: 178 VAEDRVKSGDAKISELEE---ELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXX 234
D +K + E E ++K++ S K LE +E + + +
Sbjct: 2773 TKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVM 2832
Query: 235 XXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSL 270
+ +K+L++ ++ E D+Y SL
Sbjct: 2833 DTKVDELTTE-IKELKETLEEKTKEADEYLDKYCSL 2867
Score = 34.7 bits (76), Expect = 0.37
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 8/134 (5%)
Query: 42 EVRELQKKLAQVEE-DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 100
E+ EL ++ ++E + LN+ K+ K E + E ++ L+ + +Q + L
Sbjct: 968 EIEELTQENGTLKEINASLNQEKMNLIQKS-ESFANYIDEREKSISELSDQYKQEKLILL 1026
Query: 101 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+ E +G A + L + ++A E N + L N E QLKEA A++
Sbjct: 1027 QRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEA--FAKE--- 1081
Query: 161 KSDEVSRKLAFVED 174
E KLAF E+
Sbjct: 1082 -HQEFLTKLAFAEE 1094
Score = 32.3 bits (70), Expect = 2.0
Identities = 53/238 (22%), Positives = 112/238 (47%), Gaps = 20/238 (8%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARD---ANLRAEK--VNEEVRELQKKLAQVEED 56
D +K K ++ +D+ +Q A AN+ E+ + E E + + Q ++
Sbjct: 765 DLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSERSECRLEADQSPKN 824
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE--RSGTAQ--QK 112
+ +N+++ LE +++ + + + L + +IEE+L K+E+ +S A+ Q+
Sbjct: 825 SAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQR 884
Query: 113 LLEAQQ--SADEN--NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
+ + Q+ SA +N LEN+ ++ + D++ + E + L + D + ++
Sbjct: 885 ISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSL-KE 943
Query: 169 LAFVEDELEVAEDRVKSGDAKISELE-EELKVVGNSLKSLEVS--EEKAN--QRVEEF 221
L + + L + E + S +++ E EEL +LK + S +EK N Q+ E F
Sbjct: 944 LQLLSETLSL-EKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESF 1000
Score = 31.9 bits (69), Expect = 2.6
Identities = 33/166 (19%), Positives = 68/166 (40%), Gaps = 14/166 (8%)
Query: 66 QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
+A + ++E E QL + E ++ +E L+K +++ + + E EN R
Sbjct: 15 RALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQK---VENEKTEGTNLKRENQR 71
Query: 126 M---CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
+ C+ LE Q+ + +Q+ + +++ ++L + ELE ++
Sbjct: 72 LMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQA 131
Query: 183 VKSGDAKISELEEELKVVGNSL--------KSLEVSEEKANQRVEE 220
+S D ++ K+ L E +EK N+ VEE
Sbjct: 132 AQSADVSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEE 177
Score = 31.9 bits (69), Expect = 2.6
Identities = 30/159 (18%), Positives = 71/159 (44%), Gaps = 3/159 (1%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
+K + M+ EK+N K + E + +++ + NE VR L+ + ++ N L
Sbjct: 627 EKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVL 686
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ + ++E ++ + + ++K Q +IE K+ + +G + + Q ++E
Sbjct: 687 DSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEI 746
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
+ ++ + E D L + K+A L+ + +S
Sbjct: 747 MDKDRCYQDLHAEYESLRDLLKS--KDASLVTNEDHQRS 783
Score = 31.5 bits (68), Expect = 3.5
Identities = 22/96 (22%), Positives = 52/96 (54%), Gaps = 4/96 (4%)
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-EERSGTAQQKLLEAQQSADEN 123
E + LE+ E+++ E++ N+++Q++E+ L +E +Q L E +Q +
Sbjct: 1557 EVYRQSLEKLEEKM---ESQGIMKNKEIQELEQLLSSERQELDCLRKQYLSENEQWQQKL 1613
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 159
+ +E++ ++++ +QL+ +L+ ARL + D
Sbjct: 1614 TSVTLEMESKLAAEKKQTEQLSLELEVARLQLQGLD 1649
Score = 31.5 bits (68), Expect = 3.5
Identities = 21/107 (19%), Positives = 53/107 (49%), Gaps = 6/107 (5%)
Query: 40 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT-ATEAEVAALNRKVQQIEED 98
N+E++EL++ L+ ++L + + N+ ++K +T E+++AA ++ +Q+ +
Sbjct: 1578 NKEIQELEQLLSSERQELDCLRKQYLSENEQWQQKLTSVTLEMESKLAAEKKQTEQLSLE 1637
Query: 99 LEKSE---ERSGTAQQKLL--EAQQSADENNRMCKVLENRAQQDEER 140
LE + + + + LL + + + N C + + + ER
Sbjct: 1638 LEVARLQLQGLDLSSRSLLGIDTEDAIQGRNESCDISKEHTSETTER 1684
Score = 31.5 bits (68), Expect = 3.5
Identities = 41/208 (19%), Positives = 90/208 (43%), Gaps = 27/208 (12%)
Query: 31 DANLRAEKVNEEVRELQKKL--------AQVEEDLILNK--NKLEQANKDLEEKEKQLTA 80
D + + E + E++EL KL ++E + L K +L++ N DL EK + +
Sbjct: 1792 DRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSC 1851
Query: 81 TEAEVAALNRKVQQIEEDLE-----KSEERSGTAQQKLLEA--QQSADENNRMCKVLENR 133
E+ + + DLE S E G K+ ++ ++ D N + ++ +
Sbjct: 1852 DHQELLQRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVENELSRIRSEK 1911
Query: 134 AQQDEERMD-QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 192
A + E + + ++ + L + D ++ + + + +E+EL V ++ ++
Sbjct: 1912 ASIEHEALYLEADLEVVQTEKLCLEKDNENKQ--KVIVCLEEELSVV-------TSERNQ 1962
Query: 193 LEEELKVVGNSLKSLEVSEEKANQRVEE 220
L EL + +L+ EK ++ +E
Sbjct: 1963 LRGELDTMSKKTTALDQLSEKMKEKTQE 1990
Score = 30.3 bits (65), Expect = 8.0
Identities = 40/184 (21%), Positives = 84/184 (45%), Gaps = 18/184 (9%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ-----KKLAQVEE 55
M +K K + LE + + E + N + + ++ EV+E+ +L Q+E
Sbjct: 1157 MKVMKTKHECQNLESEPIRNSVKERESERNQCNFKPQ-MDLEVKEISLDSYNAQLVQLEA 1215
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE-----DLE-KSEERSGTA 109
L + KL+++ K+ E + +L ++ N + Q +E D E +EE+ +
Sbjct: 1216 MLRNKELKLQESEKEKECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYISG 1275
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQQDE-ERMDQLTNQLKEARLLAEDADGKSD--EVS 166
+L +Q D + C + + +E E++ ++ Q ++ L+ E D +S+ +
Sbjct: 1276 PHELSTSQN--DNAHLQCSLQTTMNKLNELEKICEIL-QAEKYELVTELNDSRSECITAT 1332
Query: 167 RKLA 170
RK+A
Sbjct: 1333 RKMA 1336
>AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 60.1 bits (139), Expect = 9e-09
Identities = 49/276 (17%), Positives = 120/276 (43%), Gaps = 7/276 (2%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D +K +++ ++ E + A + +A ++ E + ++ + + L +E D++ +
Sbjct: 2332 DLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIR 2391
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ E +L++++++++ E ++ +Q+ E++ + +E+S TA + L Q
Sbjct: 2392 SEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEML---QTQLK 2448
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E N L N + + + L++Q++ L DE ++ +
Sbjct: 2449 ELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQ 2508
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXX 241
V+ G K+ + +EE+ + N ++ E K +Q E
Sbjct: 2509 EVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELE-- 2566
Query: 242 XXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDST 277
+ ++ LQ + L+D L + + YK+L +E++ T
Sbjct: 2567 --QKIQVLQSKNASLQDTLEVLQSSYKNLENELELT 2600
Score = 56.8 bits (131), Expect = 8e-08
Identities = 46/222 (20%), Positives = 101/222 (45%), Gaps = 14/222 (6%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-------QKKLAQVE 54
+ +K+K Q ++ + + E + ++ + ++ +V EL Q+KL +E
Sbjct: 1982 EKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLE 2041
Query: 55 ED---LILNK----NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 107
+D L L K N++ Q NK+ E K+ + +A ++ + + + + LE + G
Sbjct: 2042 KDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKG 2101
Query: 108 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 167
+L Q+ + R + L R + DE++ + +LKE + K + + R
Sbjct: 2102 EFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLER 2161
Query: 168 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 209
+L E+ E+ ++ A++ L+ +++ + SLK E+
Sbjct: 2162 ELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFEL 2203
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/218 (17%), Positives = 96/218 (44%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D++K K++ ++ E + + + A ++ E + ++ E+ + L E DL+ +
Sbjct: 2150 DSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 2209
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ E K ++EK+ QL+ + +++ +++ E+ + +E S TA + L + +
Sbjct: 2210 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELN 2269
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E + + E+ +D + + R E + + +K V +L+ +E
Sbjct: 2270 EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEH 2329
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
++ LE EL++ + + + E + VE
Sbjct: 2330 HADLLKGRVENLERELEIARTNQEHAALEAENSKGEVE 2367
Score = 54.0 bits (124), Expect = 6e-07
Identities = 56/278 (20%), Positives = 116/278 (41%), Gaps = 9/278 (3%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 65
+K + +EK+ ++K C + + ++ + + L++KL ++ EDL + E
Sbjct: 323 EKAKVELIEKEKVLNK---CRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAE 379
Query: 66 QANKDLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
A LE+K K+ + E++ R Q ++++ + + R Q+L +A+ +
Sbjct: 380 SARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKAR---LTQELQQAKNMHNVLQ 436
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
L + QQ E +++ +L A + + K +E+ R + ++ E + + +
Sbjct: 437 AELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSE 496
Query: 185 SGDAKISELEEELKVVGNSL-KSLEVSEE-KANQRVEEFXXXXXXXXXXXXXXXXXXXXX 242
++ LE ELK + L +S +EE KA +E
Sbjct: 497 QKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKL 556
Query: 243 XKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
V L+K+ D +D L + + L D++ T E
Sbjct: 557 KLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKE 594
Score = 54.0 bits (124), Expect = 6e-07
Identities = 52/282 (18%), Positives = 117/282 (41%), Gaps = 11/282 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED---L 57
+D + KK A+ + +K E + + EV+E + L + D L
Sbjct: 1967 LDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSEL 2026
Query: 58 ILNKNKLEQANKDLEEKEKQLTATEAE----VAALNRKVQQIEEDLEKSEERSGTAQQKL 113
+ +K L++ + LE+ + L+ T+ E +A LN++ + + ++ E + R + +
Sbjct: 2027 LKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEK 2086
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
L ++ + R +E + QL +++ R+ E + K ++ KL E
Sbjct: 2087 LNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERE 2146
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXX 233
E + +D+V++ + ++ EE ++V ++ + E ++EE
Sbjct: 2147 RENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLV 2206
Query: 234 XXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMD 275
K +++ Q ++ L+ L +KSL +E +
Sbjct: 2207 TLRSEKENLTKQIQEKQGQLSELDKLL----SSFKSLLEEKE 2244
Score = 46.8 bits (106), Expect = 9e-05
Identities = 41/223 (18%), Positives = 98/223 (43%), Gaps = 4/223 (1%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
++++ ++ EK N + + + LR EEV +L++ + ++ + ++
Sbjct: 2073 ESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADE 2132
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
K + L+E+E++ + + +V L R++Q EE+ E + ++ ++ + +
Sbjct: 2133 KKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIE 2192
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED-ELEVAE 180
E R KV E + LT Q++E + + D L E E+++ E
Sbjct: 2193 EMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKE 2252
Query: 181 D---RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ V+ ++ EL E + + + ++ +E+ + +EE
Sbjct: 2253 ESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEE 2295
Score = 46.4 bits (105), Expect = 1e-04
Identities = 45/223 (20%), Positives = 96/223 (43%), Gaps = 15/223 (6%)
Query: 65 EQANKDLEEKEKQLTATEA--EVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
EQ + E E +L A ++ A L +V +E LE ++ + Q++ E Q E
Sbjct: 803 EQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGE 862
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED---ELEVA 179
+ EN + ++ + + L ED + V+ L+ +E+ EL++
Sbjct: 863 ------IEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLL 916
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D+V++ A+I EL++ ++ +SLK L++ E + +E
Sbjct: 917 NDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQEN 976
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
T+K++ +++ + L + + + DE + + +EL+
Sbjct: 977 G----TLKEINASLNQEKMNLIQKSESFANYIDEREKSISELS 1015
Score = 44.0 bits (99), Expect = 6e-04
Identities = 46/258 (17%), Positives = 97/258 (37%), Gaps = 9/258 (3%)
Query: 16 DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKE 75
DN D+ +++ D ++ E ++ + +E DL + + + KD E K+
Sbjct: 1884 DNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQ 1943
Query: 76 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 135
K + E E++ + + Q+ +L+ T +K Q +++ + LE+
Sbjct: 1944 KVIVCLEEELSVVTSERNQLRGELD-------TMSKKTTALDQLSEKMKEKTQELESHQS 1996
Query: 136 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 195
+ + ++KE L + E+ + ++++L+ E ++ ELE
Sbjct: 1997 ECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELEN 2056
Query: 196 ELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDR 255
++ + + L E R+ E + Q+EV +
Sbjct: 2057 QIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQ 2116
Query: 256 LEDELGINKDRYKSLADE 273
L GI K R + ADE
Sbjct: 2117 L--RRGIEKLRVRIEADE 2132
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/120 (24%), Positives = 58/120 (48%), Gaps = 3/120 (2%)
Query: 99 LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL---A 155
L+K +E G + E QQ + + + L+ + Q+ E + TN +E + L
Sbjct: 17 LQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEIC 76
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
E + ++S +L E ++ E ++ SG +I +LE+ELK + L+ + + + A+
Sbjct: 77 ESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSAD 136
Score = 40.7 bits (91), Expect = 0.006
Identities = 33/127 (25%), Positives = 68/127 (53%), Gaps = 11/127 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D +KK+ Q + + D+ +A +Q+ + N + E N + RE Q+ L ++ E L
Sbjct: 27 LDKLKKEKQQRQFQLDSL--EAALQKQKQKVENEKTEGTNLK-RENQR-LMEICESLEKT 82
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K K+ +L+ KE Q+ E ++ + ++++++E++L++ + +QQ A QSA
Sbjct: 83 KQKISH---ELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQ----AAQSA 135
Query: 121 DENNRMC 127
D + C
Sbjct: 136 DVSLNPC 142
Score = 40.7 bits (91), Expect = 0.006
Identities = 40/189 (21%), Positives = 80/189 (42%), Gaps = 3/189 (1%)
Query: 33 NLRAEKVNEEVRELQKKLAQVEEDLILNKNK-LEQANKDLEEKEKQLTATEAEVAALNRK 91
+L EK E++ ++ VE ++ N+ K L +A L ++ + ATE + +
Sbjct: 2238 SLLEEKEQAEIQIKEESKTAVE--MLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEE 2295
Query: 92 VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA 151
Q+ +EK R ++K L Q E+ +L+ R + E ++ + A
Sbjct: 2296 EHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHA 2355
Query: 152 RLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSE 211
L AE++ G+ + + K+ + L E V + ++ L EL+ + LE+
Sbjct: 2356 ALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIIN 2415
Query: 212 EKANQRVEE 220
++E
Sbjct: 2416 SSFENILQE 2424
Score = 37.5 bits (83), Expect = 0.053
Identities = 52/216 (24%), Positives = 102/216 (47%), Gaps = 38/216 (17%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE-------EKEK-------QLTATE 82
+++ ++ EL+ +L E+++ NK ++ LE EKEK +L T
Sbjct: 288 QELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTT 347
Query: 83 AE-------VAALNRKVQQIEEDL----EKSEERSGTAQQKLLEAQQS-ADENNRMCKVL 130
A+ AL +K++++ EDL + +E + +QK+ E ++ +E +R +
Sbjct: 348 AQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSF 407
Query: 131 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV-------AEDRV 183
+ Q+ + +LT +L++A+ + + D+++ +E+ LE AE
Sbjct: 408 QTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAF 467
Query: 184 KSGDAKISELE---EELKVVGNSLKSLEVSEEKANQ 216
++ K +EL EE+K N LKS SE+KA +
Sbjct: 468 QASQIKENELRRSMEEMKKENNLLKS--HSEQKARE 501
Score = 37.5 bits (83), Expect = 0.053
Identities = 51/184 (27%), Positives = 91/184 (49%), Gaps = 21/184 (11%)
Query: 6 KKMQAMKLEKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
++M+A ++ + D + QQ + +L EK+ V +L+K+ ++ L ++ +
Sbjct: 524 EEMKAKNTSQETMLRDLQEKINQQ--ENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHI 581
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEAQQSADE 122
EQ N L + EK+ ++A ++AL K ++ EE E+ S + +KLL +S E
Sbjct: 582 EQLNDKLSKTEKE---SKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKE 638
Query: 123 N-----NRM--C-KVLENRAQQDEERMDQL----TNQLKEARLLAEDADGKSDEV-SRKL 169
N N + C K + ++ + ER+ L N E R L D KS EV ++KL
Sbjct: 639 NLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKL 698
Query: 170 AFVE 173
A++E
Sbjct: 699 AYME 702
Score = 37.5 bits (83), Expect = 0.053
Identities = 40/176 (22%), Positives = 84/176 (47%), Gaps = 15/176 (8%)
Query: 41 EEVRELQKKLAQVEEDL-ILNKNKLEQANKDLEE-KEKQLTATEAEVAALNRKVQQIEED 98
++++EL + +++++ L ++K+++E+ K EE E QL EAE +K Q + D
Sbjct: 2662 DQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAE-----KKHQALLLD 2716
Query: 99 LEKSEE-RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 157
K E T ++KL ++ +L++ ++ L N LK + E+
Sbjct: 2717 TNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEE-------LNNSLKATTQILEE 2769
Query: 158 ADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
+ + + ++ E E A+ ++K +LEEE +++ L L+ ++EK
Sbjct: 2770 LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEK 2825
Score = 37.1 bits (82), Expect = 0.070
Identities = 41/183 (22%), Positives = 87/183 (47%), Gaps = 17/183 (9%)
Query: 34 LRAEKVNEE-VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 92
++AE++++ V E +++++++ED ++N + + LE KEK E+ LN KV
Sbjct: 868 MKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEK-------ELQLLNDKV 920
Query: 93 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
+ + ++++ ++ + + L E Q ++ + K + + ++ +++LT +E
Sbjct: 921 ETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELT---QENG 977
Query: 153 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
L E + E + E ++R KS ISEL ++ K L L+ EE
Sbjct: 978 TLKEINASLNQEKMNLIQKSESFANYIDEREKS----ISELSDQYK--QEKLILLQRCEE 1031
Query: 213 KAN 215
N
Sbjct: 1032 TGN 1034
Score = 36.7 bits (81), Expect = 0.092
Identities = 57/269 (21%), Positives = 104/269 (38%), Gaps = 25/269 (9%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
++K+Q MK + AM+ T ++ + E + ++ L+ E L L K +L
Sbjct: 2427 QEKVQ-MKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQL 2485
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
Q L+E + ++ V L ++V+ ++ LEK +E + ++ + +Q
Sbjct: 2486 LQG---LDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQ------ 2536
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
L ++ Q E Q E R L + + K + K A ++D LEV + K
Sbjct: 2537 -----LVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYK 2591
Query: 185 SGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXK 244
+ LE EL++ S EK N+ +
Sbjct: 2592 N-------LENELELTKMDKMSF---VEKVNKMTAKETELQREMHEMAQKTAELQEELSG 2641
Query: 245 TVKKLQKEVDRLEDELGINKDRYKSLADE 273
+L E+ L +E+ +KD+ K L E
Sbjct: 2642 EKNRLAGELQLLLEEIKSSKDQLKELTLE 2670
Score = 36.3 bits (80), Expect = 0.12
Identities = 45/215 (20%), Positives = 87/215 (40%), Gaps = 8/215 (3%)
Query: 13 LEKDNA-MDKADTC-EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKD 70
LEKDN K C E++ ++ E+ + KK +++ K K ++
Sbjct: 1935 LEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESH 1994
Query: 71 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
E + EAEV +Q + D+ + + Q+KL ++ + + L
Sbjct: 1995 QSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCEL 2054
Query: 131 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 190
EN+ Q + + L + + + ++D + VS+ L E R+ S ++
Sbjct: 2055 ENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEV 2114
Query: 191 SELE---EELKV--VGNSLKSLEVSEEKANQRVEE 220
+L E+L+V + K L ++ EK +R E
Sbjct: 2115 HQLRRGIEKLRVRIEADEKKQLHIA-EKLKERERE 2148
Score = 35.9 bits (79), Expect = 0.16
Identities = 33/139 (23%), Positives = 54/139 (38%)
Query: 82 EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
E EV +Q + D S + ++ L + + E LE R Q E+ M
Sbjct: 249 EQEVTPSRSTLQIGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEM 308
Query: 142 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 201
N+ +E +L E A + E + L DEL + K + LE++LK +
Sbjct: 309 KGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLT 368
Query: 202 NSLKSLEVSEEKANQRVEE 220
L + E A +E+
Sbjct: 369 EDLSCQRQNAESARCSLEQ 387
Score = 35.1 bits (77), Expect = 0.28
Identities = 47/276 (17%), Positives = 115/276 (41%), Gaps = 10/276 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ +++ K++K + ++K + + + ++ ++ ELQ++L+ + L
Sbjct: 2593 LENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQL 2652
Query: 64 LEQANKDLEEKEKQLTATEAEV-AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS--- 119
L + K +++ K+LT +E+ +L+ + E K E Q +L EA++
Sbjct: 2653 LLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQA 2712
Query: 120 --ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
D N + ++ ++ + + L++Q E LL + ++ + +E+ +
Sbjct: 2713 LLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKK 2772
Query: 178 VAEDRVKSGDAKISELEE---ELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXX 234
D +K + E E ++K++ S K LE +E + + +
Sbjct: 2773 TKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVM 2832
Query: 235 XXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSL 270
+ +K+L++ ++ E D+Y SL
Sbjct: 2833 DTKVDELTTE-IKELKETLEEKTKEADEYLDKYCSL 2867
Score = 34.7 bits (76), Expect = 0.37
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 8/134 (5%)
Query: 42 EVRELQKKLAQVEE-DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 100
E+ EL ++ ++E + LN+ K+ K E + E ++ L+ + +Q + L
Sbjct: 968 EIEELTQENGTLKEINASLNQEKMNLIQKS-ESFANYIDEREKSISELSDQYKQEKLILL 1026
Query: 101 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+ E +G A + L + ++A E N + L N E QLKEA A++
Sbjct: 1027 QRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEA--FAKE--- 1081
Query: 161 KSDEVSRKLAFVED 174
E KLAF E+
Sbjct: 1082 -HQEFLTKLAFAEE 1094
Score = 32.3 bits (70), Expect = 2.0
Identities = 53/238 (22%), Positives = 112/238 (47%), Gaps = 20/238 (8%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARD---ANLRAEK--VNEEVRELQKKLAQVEED 56
D +K K ++ +D+ +Q A AN+ E+ + E E + + Q ++
Sbjct: 765 DLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSERSECRLEADQSPKN 824
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE--RSGTAQ--QK 112
+ +N+++ LE +++ + + + L + +IEE+L K+E+ +S A+ Q+
Sbjct: 825 SAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQR 884
Query: 113 LLEAQQ--SADEN--NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
+ + Q+ SA +N LEN+ ++ + D++ + E + L + D + ++
Sbjct: 885 ISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSL-KE 943
Query: 169 LAFVEDELEVAEDRVKSGDAKISELE-EELKVVGNSLKSLEVS--EEKAN--QRVEEF 221
L + + L + E + S +++ E EEL +LK + S +EK N Q+ E F
Sbjct: 944 LQLLSETLSL-EKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESF 1000
Score = 31.9 bits (69), Expect = 2.6
Identities = 33/166 (19%), Positives = 68/166 (40%), Gaps = 14/166 (8%)
Query: 66 QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
+A + ++E E QL + E ++ +E L+K +++ + + E EN R
Sbjct: 15 RALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQK---VENEKTEGTNLKRENQR 71
Query: 126 M---CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
+ C+ LE Q+ + +Q+ + +++ ++L + ELE ++
Sbjct: 72 LMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQA 131
Query: 183 VKSGDAKISELEEELKVVGNSL--------KSLEVSEEKANQRVEE 220
+S D ++ K+ L E +EK N+ VEE
Sbjct: 132 AQSADVSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEE 177
Score = 31.9 bits (69), Expect = 2.6
Identities = 30/159 (18%), Positives = 71/159 (44%), Gaps = 3/159 (1%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
+K + M+ EK+N K + E + +++ + NE VR L+ + ++ N L
Sbjct: 627 EKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVL 686
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ + ++E ++ + + ++K Q +IE K+ + +G + + Q ++E
Sbjct: 687 DSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEI 746
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
+ ++ + E D L + K+A L+ + +S
Sbjct: 747 MDKDRCYQDLHAEYESLRDLLKS--KDASLVTNEDHQRS 783
Score = 31.5 bits (68), Expect = 3.5
Identities = 22/96 (22%), Positives = 52/96 (54%), Gaps = 4/96 (4%)
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-EERSGTAQQKLLEAQQSADEN 123
E + LE+ E+++ E++ N+++Q++E+ L +E +Q L E +Q +
Sbjct: 1557 EVYRQSLEKLEEKM---ESQGIMKNKEIQELEQLLSSERQELDCLRKQYLSENEQWQQKL 1613
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 159
+ +E++ ++++ +QL+ +L+ ARL + D
Sbjct: 1614 TSVTLEMESKLAAEKKQTEQLSLELEVARLQLQGLD 1649
Score = 31.5 bits (68), Expect = 3.5
Identities = 21/107 (19%), Positives = 53/107 (49%), Gaps = 6/107 (5%)
Query: 40 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT-ATEAEVAALNRKVQQIEED 98
N+E++EL++ L+ ++L + + N+ ++K +T E+++AA ++ +Q+ +
Sbjct: 1578 NKEIQELEQLLSSERQELDCLRKQYLSENEQWQQKLTSVTLEMESKLAAEKKQTEQLSLE 1637
Query: 99 LEKSE---ERSGTAQQKLL--EAQQSADENNRMCKVLENRAQQDEER 140
LE + + + + LL + + + N C + + + ER
Sbjct: 1638 LEVARLQLQGLDLSSRSLLGIDTEDAIQGRNESCDISKEHTSETTER 1684
Score = 31.5 bits (68), Expect = 3.5
Identities = 41/208 (19%), Positives = 90/208 (43%), Gaps = 27/208 (12%)
Query: 31 DANLRAEKVNEEVRELQKKL--------AQVEEDLILNK--NKLEQANKDLEEKEKQLTA 80
D + + E + E++EL KL ++E + L K +L++ N DL EK + +
Sbjct: 1792 DRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSC 1851
Query: 81 TEAEVAALNRKVQQIEEDLE-----KSEERSGTAQQKLLEA--QQSADENNRMCKVLENR 133
E+ + + DLE S E G K+ ++ ++ D N + ++ +
Sbjct: 1852 DHQELLQRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVENELSRIRSEK 1911
Query: 134 AQQDEERMD-QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 192
A + E + + ++ + L + D ++ + + + +E+EL V ++ ++
Sbjct: 1912 ASIEHEALYLEADLEVVQTEKLCLEKDNENKQ--KVIVCLEEELSVV-------TSERNQ 1962
Query: 193 LEEELKVVGNSLKSLEVSEEKANQRVEE 220
L EL + +L+ EK ++ +E
Sbjct: 1963 LRGELDTMSKKTTALDQLSEKMKEKTQE 1990
Score = 30.3 bits (65), Expect = 8.0
Identities = 40/184 (21%), Positives = 84/184 (45%), Gaps = 18/184 (9%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ-----KKLAQVEE 55
M +K K + LE + + E + N + + ++ EV+E+ +L Q+E
Sbjct: 1157 MKVMKTKHECQNLESEPIRNSVKERESERNQCNFKPQ-MDLEVKEISLDSYNAQLVQLEA 1215
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE-----DLE-KSEERSGTA 109
L + KL+++ K+ E + +L ++ N + Q +E D E +EE+ +
Sbjct: 1216 MLRNKELKLQESEKEKECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYISG 1275
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQQDE-ERMDQLTNQLKEARLLAEDADGKSD--EVS 166
+L +Q D + C + + +E E++ ++ Q ++ L+ E D +S+ +
Sbjct: 1276 PHELSTSQN--DNAHLQCSLQTTMNKLNELEKICEIL-QAEKYELVTELNDSRSECITAT 1332
Query: 167 RKLA 170
RK+A
Sbjct: 1333 RKMA 1336
>AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb
protein.
Length = 1939
Score = 60.1 bits (139), Expect = 9e-09
Identities = 53/205 (25%), Positives = 106/205 (51%), Gaps = 19/205 (9%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 73
E ++ + +A E++A+ A A + EE+++ Q A +E + KN +EQ KDL
Sbjct: 1744 EMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MKKN-MEQTVKDL-- 1797
Query: 74 KEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
QL EAE AL +++Q++E + + E + Q+ +EA + ++ R K L
Sbjct: 1798 ---QLRLGEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKEL 1854
Query: 131 ENRAQQD-------EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
+ ++D ++ +D+L ++K + AE+A+ +S+ K ++ ELE AE+R
Sbjct: 1855 TYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAEERA 1914
Query: 184 KSGDAKISELEEELKVVGNSLKSLE 208
++++++L + + V + S E
Sbjct: 1915 DIAESQVNKLRVKSREVHTKVISEE 1939
Score = 57.6 bits (133), Expect = 5e-08
Identities = 47/225 (20%), Positives = 105/225 (46%), Gaps = 8/225 (3%)
Query: 4 IKKKMQA---MKLEKDNAMDKAD-TCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDL 57
IK K+Q +K + A D+ + E A+ L E ++ +++ +L+ LA+VE++
Sbjct: 913 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 972
Query: 58 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
+NK++ +++ ++ + E AL QQ +DL+ E++ T + + +
Sbjct: 973 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLE 1032
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
Q D+ + + E +L LK A+ D + +++ KL E E+
Sbjct: 1033 QQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMS 1092
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSL--EVSEEKANQRVEE 220
+ +++ A +L++++K + ++ L E+ E+A++ E
Sbjct: 1093 NLQGKIEDEQALAMQLQKKIKELQARIEELEEEIEAERASRAKAE 1137
Score = 57.6 bits (133), Expect = 5e-08
Identities = 56/277 (20%), Positives = 127/277 (45%), Gaps = 18/277 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++K+ +K+E ++ +T + + + +++ E++ K + E+ ++N+
Sbjct: 1221 LEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTK--EEEQQRLINELS 1278
Query: 64 LEQANKDLEEKE--KQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQQKLLEAQ 117
++A E E +QL +A V+ L+R QQIEE L++ E A+ L A
Sbjct: 1279 AQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEE-LKRQLEEETKAKSTLAHAL 1337
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
QSA + C +L + ++++E +L + +A +E A ++ + + E ELE
Sbjct: 1338 QSARHD---CDLLREQYEEEQEAKAELQRGMSKAN--SEVAQWRTKYETDAIQRTE-ELE 1391
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXX 237
A+ ++ ++ + EE ++ V + SLE ++++ VE+
Sbjct: 1392 EAKKKLAQ---RLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDK 1448
Query: 238 XXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
K + + +++ + + EL ++ +SL+ E+
Sbjct: 1449 KQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTEL 1485
Score = 56.8 bits (131), Expect = 8e-08
Identities = 46/261 (17%), Positives = 116/261 (44%), Gaps = 8/261 (3%)
Query: 5 KKKMQAMKLEKDNAMDKADT-CEQQARDANLRAEKVNEEVRELQK---KLAQVEEDLILN 60
+ K + +++ +++A Q+ +DA E VN + L+K +L EDL+++
Sbjct: 1376 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMID 1435
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ A L++K++ AE +K ++ + +LE S++ S + +L + + +
Sbjct: 1436 VERSNAACIALDKKQRNFDKVLAE---WKQKYEETQAELEASQKESRSLSTELFKVKNAY 1492
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+E+ + L+ + ++ + LT Q+ E + + ++ + + ++ LE AE
Sbjct: 1493 EESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAE 1552
Query: 181 DRVKSGDAKISELEEELKVVGNSL-KSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
++ + KI ++ EL V + + + + +E+ +Q
Sbjct: 1553 ASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSR 1612
Query: 240 XXXXKTVKKLQKEVDRLEDEL 260
+ KK++ +++ +E +L
Sbjct: 1613 NDALRIKKKMEGDLNEMEIQL 1633
Score = 50.0 bits (114), Expect = 9e-06
Identities = 39/205 (19%), Positives = 90/205 (43%), Gaps = 7/205 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++ + ++ EK +K ++ + K+ +E + LQ+ Q +DL +
Sbjct: 958 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQME 1017
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
++K+ K + E+Q+ E + + +E K E AQ+ ++
Sbjct: 1018 EDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDT---- 1073
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
EN++ + L + ++ E M L ++++ + LA K E+ ++ +E+E+E
Sbjct: 1074 -ENDK--QQLNEKLKKKEFEMSNLQGKIEDEQALAMQLQKKIKELQARIEELEEEIEAER 1130
Query: 181 DRVKSGDAKISELEEELKVVGNSLK 205
+ + S+L EL+ + L+
Sbjct: 1131 ASRAKAEKQRSDLSRELEEISERLE 1155
Score = 50.0 bits (114), Expect = 9e-06
Identities = 44/285 (15%), Positives = 118/285 (41%), Gaps = 1/285 (0%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+++++ + A +++A+ E + ++ N + E + L + L
Sbjct: 1598 VESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDT 1657
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ L+ A + ++ ++QL E + +V+++ LE++E A+Q+LL+A +
Sbjct: 1658 QLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERV 1717
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L N ++ E + Q+ ++++ A +A+ K+ + A + +EL+ +
Sbjct: 1718 QLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQ 1777
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE-VSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
D + +E+ +K + L E ++ + +++++
Sbjct: 1778 DTSAHLERMKKNMEQTVKDLQLRLGEAEQLALKGGKKQIQKLEARVRELESEVESEQKHN 1837
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAGY 284
K ++K ++ V L + ++ L D +D ++ Y
Sbjct: 1838 VEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAY 1882
Score = 49.2 bits (112), Expect = 2e-05
Identities = 45/239 (18%), Positives = 97/239 (40%), Gaps = 8/239 (3%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E + ++ RAE E EL K ++E++ K ++ L + EK+ ATE +V
Sbjct: 920 EAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 979
Query: 86 AALNRKVQQIEEDLEK-SEERSG---TAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
L ++ ++E + K ++E+ QQ L + Q D+ N + K QQ +
Sbjct: 980 KNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQ----V 1035
Query: 142 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 201
D L L++ + L D + ++ L ++ E+ + + K+ + E E+ +
Sbjct: 1036 DDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQ 1095
Query: 202 NSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
++ + + ++++E K L +E++ + + L
Sbjct: 1096 GKIEDEQALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERL 1154
Score = 48.0 bits (109), Expect = 4e-05
Identities = 49/250 (19%), Positives = 101/250 (40%), Gaps = 13/250 (5%)
Query: 12 KLEKDN-AMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKD 70
KL K+ A+ +A +Q D + +KVN + + + KL Q +DL + LEQ K
Sbjct: 995 KLTKEKKALQEAH--QQTLDDLQMEEDKVNT-LTKAKTKLEQQVDDL---EGSLEQEKKL 1048
Query: 71 LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
+ E+ E ++ E D ++ E+ + ++ Q ++ + L
Sbjct: 1049 CMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAMQL 1108
Query: 131 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 190
+ + ++ + R+++L +++ R A+ + ++SR+L + + LE ++G A
Sbjct: 1109 QKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLE------EAGGATS 1162
Query: 191 SELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQ 250
+++E K K EE Q + +KL+
Sbjct: 1163 AQIELNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGKQIDSLQRVKQKLE 1222
Query: 251 KEVDRLEDEL 260
KE L+ E+
Sbjct: 1223 KEKSELKMEI 1232
Score = 47.6 bits (108), Expect = 5e-05
Identities = 30/165 (18%), Positives = 80/165 (48%)
Query: 49 KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 108
K A+ E+++ K + E+ ++L + E + E ++ L ++ ++ ++ +
Sbjct: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALAD 904
Query: 109 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
A+++ + ++ + K + RA+ +EE +LT + ++ + D++
Sbjct: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
Query: 169 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
LA VE E E++VK+ +++ L+E + + K+L+ + ++
Sbjct: 965 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQ 1009
Score = 45.2 bits (102), Expect = 3e-04
Identities = 30/184 (16%), Positives = 88/184 (47%), Gaps = 1/184 (0%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+K+ ++ ++Q ++ + ++ + K ++A D ++L + A L R + +E
Sbjct: 1732 KKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1791
Query: 97 EDLEKSEERSGTAQQKLLEA-QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
+ ++ + R G A+Q L+ ++ + + LE+ + +++ + L++
Sbjct: 1792 QTVKDLQLRLGEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRV 1851
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
++ +++E + + ++D ++ + +VK+ + E EE+ V + L+ E+A
Sbjct: 1852 KELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAE 1911
Query: 216 QRVE 219
+R +
Sbjct: 1912 ERAD 1915
Score = 43.2 bits (97), Expect = 0.001
Identities = 53/221 (23%), Positives = 102/221 (46%), Gaps = 31/221 (14%)
Query: 24 TCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDLIL---NKNKLE-------QANKDL 71
+ E + AN++ E K EE+ + + K ++EE ++ KN L+ A D
Sbjct: 846 SAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADA 905
Query: 72 EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE 131
EE+ QL T+ ++ A K++++ E E EE + K + + E + LE
Sbjct: 906 EERCDQLIKTKIQLEA---KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 962
Query: 132 NRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR----KLAFVE------DELEVAED 181
+ E+ N++K L E+ G + +++ K A E D+L++ ED
Sbjct: 963 LTLAKVEKEKHATENKVKN---LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEED 1019
Query: 182 RVKSGDAKISELEEELKVVGNSL---KSLEVSEEKANQRVE 219
+V + ++LE+++ + SL K L + E+A +++E
Sbjct: 1020 KVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLE 1060
Score = 39.9 bits (89), Expect = 0.010
Identities = 42/198 (21%), Positives = 82/198 (41%), Gaps = 13/198 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 60
+ K+ +A++ +D E + K+ ++V +L+ L Q ++ DL
Sbjct: 996 LTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERA 1055
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K KLE DL+ ++ TE + LN K L+K E Q K+ + Q A
Sbjct: 1056 KRKLEG---DLKLAQESTMDTENDKQQLNEK-------LKKKEFEMSNLQGKIEDEQALA 1105
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ + K L+ R ++ EE ++ +A D + +E+S +L
Sbjct: 1106 MQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQI 1165
Query: 181 DRVKSGDAKISELEEELK 198
+ K +A+ ++ +L+
Sbjct: 1166 ELNKKREAEFQKMRRDLE 1183
Score = 30.3 bits (65), Expect = 8.0
Identities = 17/109 (15%), Positives = 55/109 (50%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
KK++Q ++ + ++ ++ +A K V+EL + + ++++ ++ +
Sbjct: 1813 KKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLV 1872
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
++ ++ ++Q E + K ++++ +LE++EER+ A+ ++
Sbjct: 1873 DKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAEERADIAESQV 1921
>AB014554-1|BAA31629.2| 1267|Homo sapiens KIAA0654 protein protein.
Length = 1267
Score = 60.1 bits (139), Expect = 9e-09
Identities = 61/270 (22%), Positives = 119/270 (44%), Gaps = 17/270 (6%)
Query: 31 DANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR 90
D+N R ++ E + + ++ Q+ E L + ++ Q ++L ++L E + L R
Sbjct: 303 DSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQR 362
Query: 91 KVQQIEEDLEKSEERSGTAQQKLLEAQQSA----DENNRMCKVL---ENRAQQDEERMDQ 143
+++ E EER T +++ L AQ+ A D N+++ L E+ +Q EE+ Q
Sbjct: 363 DLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQ 422
Query: 144 LTNQLKEARLLAEDADGKSD---EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 200
L L +A+ + K++ E+ +LA L AE+R + + ++ +LE +L+
Sbjct: 423 LAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEK 482
Query: 201 GNSL---KSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVK-KLQKEV--- 253
L + E + N+R+ E K L +E+
Sbjct: 483 NQELQRARQREKMNDDHNKRLSETVDKLLSESNERLQLHLKERMGALEEKNSLSEEIANM 542
Query: 254 DRLEDELGINKDRYKSLADEMDSTFAELAG 283
+L+DEL +NK++ + + M +L G
Sbjct: 543 KKLQDELLLNKEQLLAEMERMQMEIDQLRG 572
Score = 35.1 bits (77), Expect = 0.28
Identities = 56/277 (20%), Positives = 109/277 (39%), Gaps = 37/277 (13%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILN-------KNKLEQANKDLEEKEKQ-----LTATEAE 84
EKV E +R +++A +EE+L L+ + +L + LEE K L
Sbjct: 241 EKVRERLRMALERVAVLEEELELSNQETLNLREQLSRRRSGLEEPGKDGDGQTLANGLGP 300
Query: 85 VAALNRKVQQIEEDLEKS---------------------EERSGTAQQKLLEAQQSADEN 123
NR+ ++EE LE+ EE GTA ++L +A+++ +
Sbjct: 301 GGDSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKL 360
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
R K + + EER+ L + A+ A +D++ +LA E +E++
Sbjct: 361 QRDLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKS 420
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXX 243
+ + + +++L+ ++L E + QRV
Sbjct: 421 RQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRV----AALNKAEERHGNFEERLRQLE 476
Query: 244 KTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
+++ +E+ R +N D K L++ +D +E
Sbjct: 477 AQLEEKNQELQRARQREKMNDDHNKRLSETVDKLLSE 513
Score = 31.5 bits (68), Expect = 3.5
Identities = 41/223 (18%), Positives = 95/223 (42%), Gaps = 35/223 (15%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M +++++ E A + ++ ++A + E + E + L+K+ + +
Sbjct: 336 MSQLEEELGTAHRELGKAEEANSKLQRDLKEALAQREDMEERITTLEKRYLSAQREATSL 395
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEED--------------- 98
+ ++ +L KE +E + L +K+QQ +
Sbjct: 396 HDANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRV 455
Query: 99 --LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA--RLL 154
L K+EER G +++L + + +E N+ + RA+Q E+ D +L E +LL
Sbjct: 456 AALNKAEERHGNFEERLRQLEAQLEEKNQELQ----RARQREKMNDDHNKRLSETVDKLL 511
Query: 155 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 197
+E + + ++ +E++ ++E+ A + +L++EL
Sbjct: 512 SESNERLQLHLKERMGALEEKNSLSEE-----IANMKKLQDEL 549
>AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens
cDNA FLJ40198 fis, clone TESTI2019975, weakly similar to
TRICHOHYALIN. ).
Length = 621
Score = 59.7 bits (138), Expect = 1e-08
Identities = 35/201 (17%), Positives = 101/201 (50%), Gaps = 7/201 (3%)
Query: 5 KKKMQAMKL--EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
K++ Q K+ +++ ++ + +Q + + EK++E+ + +++ Q +E++ +
Sbjct: 404 KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 463
Query: 63 KLEQANKDLEEKEK-----QLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
K+ + + +KEK ++ E +V K+ EE + + EE+ ++K+ E +
Sbjct: 464 KIREQEEIWRQKEKMHEQEKIWKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQE 523
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
+ E + + + ++ EE++ + +++E + ++ + K E K+ E++++
Sbjct: 524 EKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 583
Query: 178 VAEDRVKSGDAKISELEEELK 198
E++++ + K+ E E L+
Sbjct: 584 EQEEKMRRQEEKMWEQEVRLR 604
Score = 52.4 bits (120), Expect = 2e-06
Identities = 31/167 (18%), Positives = 84/167 (50%), Gaps = 3/167 (1%)
Query: 34 LRAEKVNEEVREL--QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK 91
+R E+ +E E+ Q++ + +E++ K K+ + K +++EK + E ++ K
Sbjct: 446 IREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIWKQEEK-VWRQEEKMHDQEEK 504
Query: 92 VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA 151
+++ EE + + EE+ ++K+ E ++ E + E + + EE++ + ++E
Sbjct: 505 IREQEEKMWRQEEKIREQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQ 564
Query: 152 RLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELK 198
+ + K E K+ E+++ E+++ + ++ + EE+++
Sbjct: 565 EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 611
Score = 51.2 bits (117), Expect = 4e-06
Identities = 43/221 (19%), Positives = 105/221 (47%), Gaps = 12/221 (5%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE--VRELQKKLAQVEEDLILNKNK 63
++++ M EK+ + + + + + EK EE +RE +K+ Q E + + K
Sbjct: 360 RRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ-EAKMWRQEEK 418
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE----ERSGTAQQKLLEAQQS 119
+ + + + E+EK++ E ++ K+++ E+ E+ E E Q+++ ++
Sbjct: 419 IREQEEKIREQEKKMWRQEEKIHE-QEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 477
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
E ++ K E + + EE+M +++E + K E K+ E+++
Sbjct: 478 MHEQEKIWK-QEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQ 536
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+++++ + KI E EE+++ + ++ EEK ++ E+
Sbjct: 537 KEKIREQEEKIWEQEEKIR---EQEEMMQEQEEKMWEQEEK 574
Score = 50.0 bits (114), Expect = 9e-06
Identities = 40/223 (17%), Positives = 104/223 (46%), Gaps = 6/223 (2%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRA--EKVNEEVRELQKKLAQVEEDLILNK 61
+++K+Q ++ EK +++ A L +++ E L K+L V L
Sbjct: 220 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 279
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
+ E N+ +++E+++ E ++ K+Q+ EE + + EE+ ++K+ ++
Sbjct: 280 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 339
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQL--KEARLL-AEDADGKSDEVSRKLAFVEDELEV 178
E + E + EE+M +L + KE ++ E+ + +++ + ++E ++
Sbjct: 340 EKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 399
Query: 179 AE-DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
E ++ + +AK+ EE+++ ++ E + +++ E
Sbjct: 400 REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE 442
Score = 50.0 bits (114), Expect = 9e-06
Identities = 27/145 (18%), Positives = 74/145 (51%), Gaps = 1/145 (0%)
Query: 41 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 100
E++ E Q+K+ + EE + + K+ + + E+E+++ E ++ K+++ EE +
Sbjct: 476 EKMHE-QEKIWKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIR 534
Query: 101 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+ +E+ ++K+ E ++ E M + E + + EE+M + +++E +
Sbjct: 535 EQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 594
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKS 185
K E +L E++++ ++ +++
Sbjct: 595 KMWEQEVRLRQQEEKMQEHQEHLEA 619
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/126 (19%), Positives = 61/126 (48%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E++ D + + E++ ++K+ + EE + + K+ + + + E+E+++ E ++
Sbjct: 495 EEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQKEKIREQEEKIWEQEEKI 554
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
+Q+ EE + + EE+ ++K+ E ++ E R +Q EE+M +
Sbjct: 555 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 614
Query: 146 NQLKEA 151
L+ A
Sbjct: 615 EHLEAA 620
Score = 48.0 bits (109), Expect = 4e-05
Identities = 24/123 (19%), Positives = 62/123 (50%)
Query: 20 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 79
+K E++ R+ + + E++RE ++K+ + EE + K K+ + + + E+E+++
Sbjct: 496 EKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIR 555
Query: 80 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 139
E + K+ + EE + + EE+ ++K+ ++ E + E + Q+ +E
Sbjct: 556 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 615
Query: 140 RMD 142
++
Sbjct: 616 HLE 618
Score = 47.6 bits (108), Expect = 5e-05
Identities = 26/128 (20%), Positives = 65/128 (50%), Gaps = 2/128 (1%)
Query: 38 KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 97
K E+V ++K+ EE + + K+ + + + E+E+++ E ++ K+++ EE
Sbjct: 486 KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQKEKIREQEE 545
Query: 98 DLEKSEERSGTAQQKLLEAQQSA-DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
+ + EE+ ++ + E ++ ++ +MC+ E + Q+ EE+M + ++ E +
Sbjct: 546 KIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQ-EEKMQEQEEKMRRQEEKMWEQEVRLR 604
Query: 157 DADGKSDE 164
+ K E
Sbjct: 605 QQEEKMQE 612
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/199 (17%), Positives = 96/199 (48%), Gaps = 9/199 (4%)
Query: 6 KKMQAMKLEKDNAMDKADTC--EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ + M EK+ M + + E++ + L EK++E+ + +++ + EE+ I + K
Sbjct: 346 RRQEEMMWEKEEKMRRLEEMMWEKEEKIRELE-EKMHEQEKIREQEEKRQEEEKIREQEK 404
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS----EERSGTAQQKLLEAQQS 119
++ + +E+++ E ++ +K+ + EE + + EE Q+++ ++
Sbjct: 405 RQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK 464
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
E + + E +Q++ + +E ++ D + K E K+ E+++
Sbjct: 465 IREQEEIWRQKEKMHEQEKIWKQEEKVWRQEEKM--HDQEEKIREQEEKMWRQEEKIREQ 522
Query: 180 EDRVKSGDAKISELEEELK 198
E++++ + KI E +E+++
Sbjct: 523 EEKIREQEEKIREQKEKIR 541
Score = 43.2 bits (97), Expect = 0.001
Identities = 22/139 (15%), Positives = 67/139 (48%)
Query: 41 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 100
E++ + ++K+ + EE + + K+ + + + +E+++ E ++ K+++ +E +
Sbjct: 482 EKIWKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQKEKIR 541
Query: 101 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+ EE+ ++K+ E ++ E E + + EE+M + +++ + +
Sbjct: 542 EQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 601
Query: 161 KSDEVSRKLAFVEDELEVA 179
+ + K+ ++ LE A
Sbjct: 602 RLRQQEEKMQEHQEHLEAA 620
Score = 41.1 bits (92), Expect = 0.004
Identities = 41/202 (20%), Positives = 90/202 (44%), Gaps = 8/202 (3%)
Query: 22 ADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT 81
A EQ + +K + + EL K+ + +L N E+ + + +++L
Sbjct: 168 AGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLV 227
Query: 82 EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
E+E + + V++++ LE+++ QQ EA E + L+ AQ +E +
Sbjct: 228 ESEKSEIQLNVKELKRKLERAKLLL-PQQQLQAEADHLGKELQSVSAKLQ--AQVEENEL 284
Query: 142 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 201
NQ +E ++ ++ K E K+ E+++ E++++ + K+ EE +
Sbjct: 285 WNRLNQQQEEKMWRQEE--KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 342
Query: 202 NSLKSLEV---SEEKANQRVEE 220
++ E +E+ +R+EE
Sbjct: 343 EKMRRQEEMMWEKEEKMRRLEE 364
>X03445-1|CAA27174.1| 572|Homo sapiens protein ( Human mRNA for
nuclear envelope protein lamin C precursor. ).
Length = 572
Score = 59.3 bits (137), Expect = 2e-08
Identities = 67/276 (24%), Positives = 110/276 (39%), Gaps = 11/276 (3%)
Query: 10 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
A + E +A D+ ++ L KV EE +EL+ + + E DLI + +L+
Sbjct: 80 AYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEA 139
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL-EAQQSADENNRMCK 128
L KE L+ +E L ++ + + K E G A+++L E + D NR+
Sbjct: 140 LLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQT 199
Query: 129 VLENRAQQDEERMDQL--TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA-EDRVKS 185
+ E Q ++L T + E RL+ D +GK E +LA EL ED+V+
Sbjct: 200 MKEELDFQKNIYSEELRETKRRHETRLVEID-NGKQREFESRLADALQELRAQHEDQVEQ 258
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKT 245
ELE K L + S E+ + V K
Sbjct: 259 YK---KELE---KTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQ 312
Query: 246 VKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ + ++ LED L +D + L E + AE+
Sbjct: 313 LAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEM 348
Score = 34.3 bits (75), Expect = 0.49
Identities = 51/223 (22%), Positives = 98/223 (43%), Gaps = 33/223 (14%)
Query: 1 MDAIKKKMQAMKLEK-DNAMDKAD-------TCEQQARDANLRAEKVNEEVRELQKKLAQ 52
++ KK+++ K DNA A+ ++ + + +R + ++ ++ +LQK+LA
Sbjct: 256 VEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAA 315
Query: 53 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
E L ++ + ++ + + L E E+A + ++QQ ++ Q+
Sbjct: 316 KEAKL---RDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY-----------QE 361
Query: 113 LLEAQQSAD-ENNRMCKVLENRAQQDEERM---DQLTNQLKEARLLAEDAD---GKSDEV 165
LL+ + + D E + K+LE +EER+ T+Q R + + G S
Sbjct: 362 LLDIKLALDMEIHAYRKLLEG----EEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTK 417
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
RKL E ++ SG + E++EE K V KS E
Sbjct: 418 KRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNE 460
>X03444-1|CAA27173.1| 702|Homo sapiens protein ( Human mRNA for
nuclear envelope protein lamin A precursor. ).
Length = 702
Score = 59.3 bits (137), Expect = 2e-08
Identities = 67/276 (24%), Positives = 110/276 (39%), Gaps = 11/276 (3%)
Query: 10 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
A + E +A D+ ++ L KV EE +EL+ + + E DLI + +L+
Sbjct: 80 AYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEA 139
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL-EAQQSADENNRMCK 128
L KE L+ +E L ++ + + K E G A+++L E + D NR+
Sbjct: 140 LLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQT 199
Query: 129 VLENRAQQDEERMDQL--TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA-EDRVKS 185
+ E Q ++L T + E RL+ D +GK E +LA EL ED+V+
Sbjct: 200 MKEELDFQKNIYSEELRETKRRHETRLVEID-NGKQREFESRLADALQELRAQHEDQVEQ 258
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKT 245
ELE K L + S E+ + V K
Sbjct: 259 YK---KELE---KTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQ 312
Query: 246 VKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ + ++ LED L +D + L E + AE+
Sbjct: 313 LAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEM 348
Score = 34.3 bits (75), Expect = 0.49
Identities = 51/223 (22%), Positives = 98/223 (43%), Gaps = 33/223 (14%)
Query: 1 MDAIKKKMQAMKLEK-DNAMDKAD-------TCEQQARDANLRAEKVNEEVRELQKKLAQ 52
++ KK+++ K DNA A+ ++ + + +R + ++ ++ +LQK+LA
Sbjct: 256 VEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAA 315
Query: 53 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
E L ++ + ++ + + L E E+A + ++QQ ++ Q+
Sbjct: 316 KEAKL---RDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY-----------QE 361
Query: 113 LLEAQQSAD-ENNRMCKVLENRAQQDEERM---DQLTNQLKEARLLAEDAD---GKSDEV 165
LL+ + + D E + K+LE +EER+ T+Q R + + G S
Sbjct: 362 LLDIKLALDMEIHAYRKLLEG----EEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTK 417
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
RKL E ++ SG + E++EE K V KS E
Sbjct: 418 KRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNE 460
>M21664-1|AAA36344.1| 532|Homo sapiens protein ( Human alpha-myosin
heavy chain mRNA, 3' end. ).
Length = 532
Score = 59.3 bits (137), Expect = 2e-08
Identities = 50/208 (24%), Positives = 108/208 (51%), Gaps = 17/208 (8%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKKM A ++ E + A+ + E++A+ A A + EE+++ Q A +E +
Sbjct: 323 KKKMDADLSQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MK 379
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
KN +EQ KDL+ + + A + + +++Q++E + + E Q++ E+ +
Sbjct: 380 KN-MEQTIKDLQHRLDE--AEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGM 436
Query: 121 DENNRMCKVLENRAQQDEE---RMDQLTNQL----KEARLLAEDADGKSDEVSRKLAFVE 173
++ R K L + ++D++ R+ L N+L K + AE+A+ +++ K V+
Sbjct: 437 RKSERRIKELTYQTEEDKKNLLRLQDLVNKLQLKVKAYKGQAEEAEERANTNLSKFRKVQ 496
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVG 201
EL+ AE+R ++++++L + + +G
Sbjct: 497 HELDEAEERADIAESQVNKLRAKSRDIG 524
Score = 53.2 bits (122), Expect = 1e-06
Identities = 43/192 (22%), Positives = 84/192 (43%), Gaps = 4/192 (2%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 18 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 77
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
L ++ E LE + + Q+++ + + E + LE Q E +L
Sbjct: 78 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRNQLEVEKMELQ 137
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
+ L+EA E +GK + +L F + + E+ E V D ++ + + + V +SL+
Sbjct: 138 SALEEAEASLEHEEGKI--LRAQLEFNQIKAEI-ERNVAEKDEEMEQAKRNHQRVVDSLQ 194
Query: 206 -SLEVSEEKANQ 216
SL+ N+
Sbjct: 195 TSLDAETRSRNE 206
Score = 52.8 bits (121), Expect = 1e-06
Identities = 61/274 (22%), Positives = 115/274 (41%), Gaps = 20/274 (7%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDA---NLRAE-KVNEEVRELQKKLAQVEEDLIL 59
IK +++ EKD M++A Q+ D+ +L AE + EV ++KK+ E DL
Sbjct: 164 IKAEIERNVAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKM---EGDLNE 220
Query: 60 NKNKLEQANKDLEEKEKQLTA-------TEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
+ +L AN+ E +KQ+ + T+ ++ R ++E++ E R+ Q +
Sbjct: 221 MEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 280
Query: 113 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 172
L E + ++ R K+ E + ER+ L +Q + D ++ ++
Sbjct: 281 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQSEVEEA 340
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXX 232
E AE++ K + + EELK ++ LE ++ Q +++
Sbjct: 341 VQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDL------QHRLD 394
Query: 233 XXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDR 266
K ++KL+ V LE EL + R
Sbjct: 395 EAEQIALKGGKKQLQKLEARVRELEGELEAEQKR 428
Score = 49.6 bits (113), Expect = 1e-05
Identities = 50/226 (22%), Positives = 106/226 (46%), Gaps = 15/226 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 59
++ ++ +++ K+E +A+++A+ + LRA+ + N+ E+++ +A+ +E++
Sbjct: 122 LEKVRNQLEVEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERNVAEKDEEMEQ 181
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
K ++ L+ T + EV + +K +E DL + E + A + EAQ+
Sbjct: 182 AKRNHQRVVDSLQTSLDAETRSRNEVLRVKKK---MEGDLNEMEIQLSHANRMAAEAQKQ 238
Query: 120 ADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVSRKLA 170
+ K L++ + +++ + + N L +A L A + E SRKLA
Sbjct: 239 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 298
Query: 171 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
E EL +RV+ ++ + L + K + L L+ E+A Q
Sbjct: 299 --EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQSEVEEAVQ 342
Score = 49.6 bits (113), Expect = 1e-05
Identities = 34/208 (16%), Positives = 94/208 (45%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D+++ + A ++ + E + ++ N E QK++ ++ L
Sbjct: 190 VDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDT 249
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ +L+ A + ++ ++ + E L +++++ +E++E A+Q+L+E +
Sbjct: 250 QIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERV 309
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+ L N+ ++ + + QL ++++EA +A+ K+ + A + +EL+ +
Sbjct: 310 QLLHSQNTSLINQKKKMDADLSQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQ 369
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLE 208
D + +E+ +K + + L E
Sbjct: 370 DTSAHLERMKKNMEQTIKDLQHRLDEAE 397
Score = 41.1 bits (92), Expect = 0.004
Identities = 36/166 (21%), Positives = 73/166 (43%), Gaps = 19/166 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTC-----EQQARDANLRAEKVNEEVRELQKKLAQVEE 55
++ +KK M+ + + +D+A+ ++Q + R ++ E+ QK+ A+ +
Sbjct: 375 LERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVK 434
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ ++ ++++ EE +K L + V L KV+ + E++EER+ T K +
Sbjct: 435 GMRKSERRIKELTYQTEEDKKNLLRLQDLVNKLQLKVKAYKGQAEEAEERANTNLSKFRK 494
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
Q DE EER D +Q+ + R + D K
Sbjct: 495 VQHELDEA--------------EERADIAESQVNKLRAKSRDIGAK 526
>M13451-1|AAA36164.1| 572|Homo sapiens protein ( Human lamin C
mRNA, complete cds. ).
Length = 572
Score = 59.3 bits (137), Expect = 2e-08
Identities = 67/276 (24%), Positives = 110/276 (39%), Gaps = 11/276 (3%)
Query: 10 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
A + E +A D+ ++ L KV EE +EL+ + + E DLI + +L+
Sbjct: 80 AYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEA 139
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL-EAQQSADENNRMCK 128
L KE L+ +E L ++ + + K E G A+++L E + D NR+
Sbjct: 140 LLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQT 199
Query: 129 VLENRAQQDEERMDQL--TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA-EDRVKS 185
+ E Q ++L T + E RL+ D +GK E +LA EL ED+V+
Sbjct: 200 MKEELDFQKNIYSEELRETKRRHETRLVEID-NGKQREFESRLADALQELRAQHEDQVEQ 258
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKT 245
ELE K L + S E+ + V K
Sbjct: 259 YK---KELE---KTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQ 312
Query: 246 VKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ + ++ LED L +D + L E + AE+
Sbjct: 313 LAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEM 348
Score = 34.3 bits (75), Expect = 0.49
Identities = 51/223 (22%), Positives = 98/223 (43%), Gaps = 33/223 (14%)
Query: 1 MDAIKKKMQAMKLEK-DNAMDKAD-------TCEQQARDANLRAEKVNEEVRELQKKLAQ 52
++ KK+++ K DNA A+ ++ + + +R + ++ ++ +LQK+LA
Sbjct: 256 VEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAA 315
Query: 53 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
E L ++ + ++ + + L E E+A + ++QQ ++ Q+
Sbjct: 316 KEAKL---RDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY-----------QE 361
Query: 113 LLEAQQSAD-ENNRMCKVLENRAQQDEERM---DQLTNQLKEARLLAEDAD---GKSDEV 165
LL+ + + D E + K+LE +EER+ T+Q R + + G S
Sbjct: 362 LLDIKLALDMEIHAYRKLLEG----EEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTK 417
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
RKL E ++ SG + E++EE K V KS E
Sbjct: 418 KRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNE 460
>BC014507-1|AAH14507.1| 664|Homo sapiens lamin A/C protein.
Length = 664
Score = 59.3 bits (137), Expect = 2e-08
Identities = 67/276 (24%), Positives = 110/276 (39%), Gaps = 11/276 (3%)
Query: 10 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
A + E +A D+ ++ L KV EE +EL+ + + E DLI + +L+
Sbjct: 80 AYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEA 139
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL-EAQQSADENNRMCK 128
L KE L+ +E L ++ + + K E G A+++L E + D NR+
Sbjct: 140 LLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQT 199
Query: 129 VLENRAQQDEERMDQL--TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA-EDRVKS 185
+ E Q ++L T + E RL+ D +GK E +LA EL ED+V+
Sbjct: 200 MKEELDFQKNIYSEELRETKRRHETRLVEID-NGKQREFESRLADALQELRAQHEDQVEQ 258
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKT 245
ELE K L + S E+ + V K
Sbjct: 259 YK---KELE---KTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQ 312
Query: 246 VKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ + ++ LED L +D + L E + AE+
Sbjct: 313 LAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEM 348
Score = 34.3 bits (75), Expect = 0.49
Identities = 51/223 (22%), Positives = 98/223 (43%), Gaps = 33/223 (14%)
Query: 1 MDAIKKKMQAMKLEK-DNAMDKAD-------TCEQQARDANLRAEKVNEEVRELQKKLAQ 52
++ KK+++ K DNA A+ ++ + + +R + ++ ++ +LQK+LA
Sbjct: 256 VEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAA 315
Query: 53 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
E L ++ + ++ + + L E E+A + ++QQ ++ Q+
Sbjct: 316 KEAKL---RDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY-----------QE 361
Query: 113 LLEAQQSAD-ENNRMCKVLENRAQQDEERM---DQLTNQLKEARLLAEDAD---GKSDEV 165
LL+ + + D E + K+LE +EER+ T+Q R + + G S
Sbjct: 362 LLDIKLALDMEIHAYRKLLEG----EEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTK 417
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
RKL E ++ SG + E++EE K V KS E
Sbjct: 418 KRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNE 460
>BC003162-1|AAH03162.1| 572|Homo sapiens lamin A/C protein.
Length = 572
Score = 59.3 bits (137), Expect = 2e-08
Identities = 67/276 (24%), Positives = 110/276 (39%), Gaps = 11/276 (3%)
Query: 10 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
A + E +A D+ ++ L KV EE +EL+ + + E DLI + +L+
Sbjct: 80 AYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEA 139
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL-EAQQSADENNRMCK 128
L KE L+ +E L ++ + + K E G A+++L E + D NR+
Sbjct: 140 LLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQT 199
Query: 129 VLENRAQQDEERMDQL--TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA-EDRVKS 185
+ E Q ++L T + E RL+ D +GK E +LA EL ED+V+
Sbjct: 200 MKEELDFQKNIYSEELRETKRRHETRLVEID-NGKQREFESRLADALQELRAQHEDQVEQ 258
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKT 245
ELE K L + S E+ + V K
Sbjct: 259 YK---KELE---KTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQ 312
Query: 246 VKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ + ++ LED L +D + L E + AE+
Sbjct: 313 LAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEM 348
Score = 34.3 bits (75), Expect = 0.49
Identities = 51/223 (22%), Positives = 98/223 (43%), Gaps = 33/223 (14%)
Query: 1 MDAIKKKMQAMKLEK-DNAMDKAD-------TCEQQARDANLRAEKVNEEVRELQKKLAQ 52
++ KK+++ K DNA A+ ++ + + +R + ++ ++ +LQK+LA
Sbjct: 256 VEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAA 315
Query: 53 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
E L ++ + ++ + + L E E+A + ++QQ ++ Q+
Sbjct: 316 KEAKL---RDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY-----------QE 361
Query: 113 LLEAQQSAD-ENNRMCKVLENRAQQDEERM---DQLTNQLKEARLLAEDAD---GKSDEV 165
LL+ + + D E + K+LE +EER+ T+Q R + + G S
Sbjct: 362 LLDIKLALDMEIHAYRKLLEG----EEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTK 417
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
RKL E ++ SG + E++EE K V KS E
Sbjct: 418 KRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNE 460
>BC000511-1|AAH00511.1| 572|Homo sapiens lamin A/C protein.
Length = 572
Score = 59.3 bits (137), Expect = 2e-08
Identities = 67/276 (24%), Positives = 110/276 (39%), Gaps = 11/276 (3%)
Query: 10 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
A + E +A D+ ++ L KV EE +EL+ + + E DLI + +L+
Sbjct: 80 AYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEA 139
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL-EAQQSADENNRMCK 128
L KE L+ +E L ++ + + K E G A+++L E + D NR+
Sbjct: 140 LLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQT 199
Query: 129 VLENRAQQDEERMDQL--TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA-EDRVKS 185
+ E Q ++L T + E RL+ D +GK E +LA EL ED+V+
Sbjct: 200 MKEELDFQKNIYSEELRETKRRHETRLVEID-NGKQREFESRLADALQELRAQHEDQVEQ 258
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKT 245
ELE K L + S E+ + V K
Sbjct: 259 YK---KELE---KTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQ 312
Query: 246 VKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ + ++ LED L +D + L E + AE+
Sbjct: 313 LAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEM 348
Score = 34.3 bits (75), Expect = 0.49
Identities = 51/223 (22%), Positives = 98/223 (43%), Gaps = 33/223 (14%)
Query: 1 MDAIKKKMQAMKLEK-DNAMDKAD-------TCEQQARDANLRAEKVNEEVRELQKKLAQ 52
++ KK+++ K DNA A+ ++ + + +R + ++ ++ +LQK+LA
Sbjct: 256 VEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAA 315
Query: 53 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
E L ++ + ++ + + L E E+A + ++QQ ++ Q+
Sbjct: 316 KEAKL---RDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY-----------QE 361
Query: 113 LLEAQQSAD-ENNRMCKVLENRAQQDEERM---DQLTNQLKEARLLAEDAD---GKSDEV 165
LL+ + + D E + K+LE +EER+ T+Q R + + G S
Sbjct: 362 LLDIKLALDMEIHAYRKLLEG----EEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTK 417
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
RKL E ++ SG + E++EE K V KS E
Sbjct: 418 KRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNE 460
>AY847597-1|AAW32540.1| 664|Homo sapiens lamin A/C transcript
variant 1 protein.
Length = 664
Score = 59.3 bits (137), Expect = 2e-08
Identities = 67/276 (24%), Positives = 110/276 (39%), Gaps = 11/276 (3%)
Query: 10 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
A + E +A D+ ++ L KV EE +EL+ + + E DLI + +L+
Sbjct: 80 AYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEA 139
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL-EAQQSADENNRMCK 128
L KE L+ +E L ++ + + K E G A+++L E + D NR+
Sbjct: 140 LLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQT 199
Query: 129 VLENRAQQDEERMDQL--TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA-EDRVKS 185
+ E Q ++L T + E RL+ D +GK E +LA EL ED+V+
Sbjct: 200 MKEELDFQKNIYSEELRETKRRHETRLVEID-NGKQREFESRLADALQELRAQHEDQVEQ 258
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKT 245
ELE K L + S E+ + V K
Sbjct: 259 YK---KELE---KTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQ 312
Query: 246 VKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ + ++ LED L +D + L E + AE+
Sbjct: 313 LAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEM 348
Score = 34.3 bits (75), Expect = 0.49
Identities = 51/223 (22%), Positives = 98/223 (43%), Gaps = 33/223 (14%)
Query: 1 MDAIKKKMQAMKLEK-DNAMDKAD-------TCEQQARDANLRAEKVNEEVRELQKKLAQ 52
++ KK+++ K DNA A+ ++ + + +R + ++ ++ +LQK+LA
Sbjct: 256 VEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAA 315
Query: 53 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
E L ++ + ++ + + L E E+A + ++QQ ++ Q+
Sbjct: 316 KEAKL---RDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY-----------QE 361
Query: 113 LLEAQQSAD-ENNRMCKVLENRAQQDEERM---DQLTNQLKEARLLAEDAD---GKSDEV 165
LL+ + + D E + K+LE +EER+ T+Q R + + G S
Sbjct: 362 LLDIKLALDMEIHAYRKLLEG----EEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTK 417
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
RKL E ++ SG + E++EE K V KS E
Sbjct: 418 KRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNE 460
>AY847596-1|AAW32539.1| 480|Homo sapiens lamin A/C transcript
variant 1 protein.
Length = 480
Score = 59.3 bits (137), Expect = 2e-08
Identities = 67/276 (24%), Positives = 110/276 (39%), Gaps = 11/276 (3%)
Query: 10 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
A + E +A D+ ++ L KV EE +EL+ + + E DLI + +L+
Sbjct: 80 AYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEA 139
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL-EAQQSADENNRMCK 128
L KE L+ +E L ++ + + K E G A+++L E + D NR+
Sbjct: 140 LLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQT 199
Query: 129 VLENRAQQDEERMDQL--TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA-EDRVKS 185
+ E Q ++L T + E RL+ D +GK E +LA EL ED+V+
Sbjct: 200 MKEELDFQKNIYSEELRETKRRHETRLVEID-NGKQREFESRLADALQELRAQHEDQVEQ 258
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKT 245
ELE K L + S E+ + V K
Sbjct: 259 YK---KELE---KTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQ 312
Query: 246 VKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ + ++ LED L +D + L E + AE+
Sbjct: 313 LAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEM 348
Score = 34.3 bits (75), Expect = 0.49
Identities = 51/223 (22%), Positives = 98/223 (43%), Gaps = 33/223 (14%)
Query: 1 MDAIKKKMQAMKLEK-DNAMDKAD-------TCEQQARDANLRAEKVNEEVRELQKKLAQ 52
++ KK+++ K DNA A+ ++ + + +R + ++ ++ +LQK+LA
Sbjct: 256 VEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAA 315
Query: 53 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
E L ++ + ++ + + L E E+A + ++QQ ++ Q+
Sbjct: 316 KEAKL---RDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY-----------QE 361
Query: 113 LLEAQQSAD-ENNRMCKVLENRAQQDEERM---DQLTNQLKEARLLAEDAD---GKSDEV 165
LL+ + + D E + K+LE +EER+ T+Q R + + G S
Sbjct: 362 LLDIKLALDMEIHAYRKLLEG----EEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTK 417
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
RKL E ++ SG + E++EE K V KS E
Sbjct: 418 KRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNE 460
>AY528714-1|ABB04050.1| 487|Homo sapiens rhabdomyosarcoma antigen
MU-RMS-40.12 protein.
Length = 487
Score = 59.3 bits (137), Expect = 2e-08
Identities = 67/276 (24%), Positives = 110/276 (39%), Gaps = 11/276 (3%)
Query: 10 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
A + E +A D+ ++ L KV EE +EL+ + + E DLI + +L+
Sbjct: 80 AYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEA 139
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL-EAQQSADENNRMCK 128
L KE L+ +E L ++ + + K E G A+++L E + D NR+
Sbjct: 140 LLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQT 199
Query: 129 VLENRAQQDEERMDQL--TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA-EDRVKS 185
+ E Q ++L T + E RL+ D +GK E +LA EL ED+V+
Sbjct: 200 MKEELDFQKNIYSEELRETKRRHETRLVEID-NGKQREFESRLADALQELRAQHEDQVEQ 258
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKT 245
ELE K L + S E+ + V K
Sbjct: 259 YK---KELE---KTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQ 312
Query: 246 VKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ + ++ LED L +D + L E + AE+
Sbjct: 313 LAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEM 348
>AY357727-1|AAR29466.1| 614|Homo sapiens progerin protein.
Length = 614
Score = 59.3 bits (137), Expect = 2e-08
Identities = 67/276 (24%), Positives = 110/276 (39%), Gaps = 11/276 (3%)
Query: 10 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
A + E +A D+ ++ L KV EE +EL+ + + E DLI + +L+
Sbjct: 80 AYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEA 139
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL-EAQQSADENNRMCK 128
L KE L+ +E L ++ + + K E G A+++L E + D NR+
Sbjct: 140 LLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQT 199
Query: 129 VLENRAQQDEERMDQL--TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA-EDRVKS 185
+ E Q ++L T + E RL+ D +GK E +LA EL ED+V+
Sbjct: 200 MKEELDFQKNIYSEELRETKRRHETRLVEID-NGKQREFESRLADALQELRAQHEDQVEQ 258
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKT 245
ELE K L + S E+ + V K
Sbjct: 259 YK---KELE---KTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQ 312
Query: 246 VKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ + ++ LED L +D + L E + AE+
Sbjct: 313 LAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEM 348
Score = 34.3 bits (75), Expect = 0.49
Identities = 51/223 (22%), Positives = 98/223 (43%), Gaps = 33/223 (14%)
Query: 1 MDAIKKKMQAMKLEK-DNAMDKAD-------TCEQQARDANLRAEKVNEEVRELQKKLAQ 52
++ KK+++ K DNA A+ ++ + + +R + ++ ++ +LQK+LA
Sbjct: 256 VEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAA 315
Query: 53 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
E L ++ + ++ + + L E E+A + ++QQ ++ Q+
Sbjct: 316 KEAKL---RDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY-----------QE 361
Query: 113 LLEAQQSAD-ENNRMCKVLENRAQQDEERM---DQLTNQLKEARLLAEDAD---GKSDEV 165
LL+ + + D E + K+LE +EER+ T+Q R + + G S
Sbjct: 362 LLDIKLALDMEIHAYRKLLEG----EEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTK 417
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
RKL E ++ SG + E++EE K V KS E
Sbjct: 418 KRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNE 460
>AL135927-4|CAI15523.1| 614|Homo sapiens lamin A/C protein.
Length = 614
Score = 59.3 bits (137), Expect = 2e-08
Identities = 67/276 (24%), Positives = 110/276 (39%), Gaps = 11/276 (3%)
Query: 10 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
A + E +A D+ ++ L KV EE +EL+ + + E DLI + +L+
Sbjct: 80 AYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEA 139
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL-EAQQSADENNRMCK 128
L KE L+ +E L ++ + + K E G A+++L E + D NR+
Sbjct: 140 LLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQT 199
Query: 129 VLENRAQQDEERMDQL--TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA-EDRVKS 185
+ E Q ++L T + E RL+ D +GK E +LA EL ED+V+
Sbjct: 200 MKEELDFQKNIYSEELRETKRRHETRLVEID-NGKQREFESRLADALQELRAQHEDQVEQ 258
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKT 245
ELE K L + S E+ + V K
Sbjct: 259 YK---KELE---KTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQ 312
Query: 246 VKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ + ++ LED L +D + L E + AE+
Sbjct: 313 LAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEM 348
Score = 34.3 bits (75), Expect = 0.49
Identities = 51/223 (22%), Positives = 98/223 (43%), Gaps = 33/223 (14%)
Query: 1 MDAIKKKMQAMKLEK-DNAMDKAD-------TCEQQARDANLRAEKVNEEVRELQKKLAQ 52
++ KK+++ K DNA A+ ++ + + +R + ++ ++ +LQK+LA
Sbjct: 256 VEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAA 315
Query: 53 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
E L ++ + ++ + + L E E+A + ++QQ ++ Q+
Sbjct: 316 KEAKL---RDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY-----------QE 361
Query: 113 LLEAQQSAD-ENNRMCKVLENRAQQDEERM---DQLTNQLKEARLLAEDAD---GKSDEV 165
LL+ + + D E + K+LE +EER+ T+Q R + + G S
Sbjct: 362 LLDIKLALDMEIHAYRKLLEG----EEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTK 417
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
RKL E ++ SG + E++EE K V KS E
Sbjct: 418 KRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNE 460
>AL135927-3|CAI15522.1| 664|Homo sapiens lamin A/C protein.
Length = 664
Score = 59.3 bits (137), Expect = 2e-08
Identities = 67/276 (24%), Positives = 110/276 (39%), Gaps = 11/276 (3%)
Query: 10 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
A + E +A D+ ++ L KV EE +EL+ + + E DLI + +L+
Sbjct: 80 AYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEA 139
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL-EAQQSADENNRMCK 128
L KE L+ +E L ++ + + K E G A+++L E + D NR+
Sbjct: 140 LLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQT 199
Query: 129 VLENRAQQDEERMDQL--TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA-EDRVKS 185
+ E Q ++L T + E RL+ D +GK E +LA EL ED+V+
Sbjct: 200 MKEELDFQKNIYSEELRETKRRHETRLVEID-NGKQREFESRLADALQELRAQHEDQVEQ 258
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKT 245
ELE K L + S E+ + V K
Sbjct: 259 YK---KELE---KTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQ 312
Query: 246 VKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ + ++ LED L +D + L E + AE+
Sbjct: 313 LAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEM 348
Score = 34.3 bits (75), Expect = 0.49
Identities = 51/223 (22%), Positives = 98/223 (43%), Gaps = 33/223 (14%)
Query: 1 MDAIKKKMQAMKLEK-DNAMDKAD-------TCEQQARDANLRAEKVNEEVRELQKKLAQ 52
++ KK+++ K DNA A+ ++ + + +R + ++ ++ +LQK+LA
Sbjct: 256 VEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAA 315
Query: 53 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
E L ++ + ++ + + L E E+A + ++QQ ++ Q+
Sbjct: 316 KEAKL---RDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY-----------QE 361
Query: 113 LLEAQQSAD-ENNRMCKVLENRAQQDEERM---DQLTNQLKEARLLAEDAD---GKSDEV 165
LL+ + + D E + K+LE +EER+ T+Q R + + G S
Sbjct: 362 LLDIKLALDMEIHAYRKLLEG----EEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTK 417
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
RKL E ++ SG + E++EE K V KS E
Sbjct: 418 KRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNE 460
>AL135927-2|CAI15520.1| 465|Homo sapiens lamin A/C protein.
Length = 465
Score = 59.3 bits (137), Expect = 2e-08
Identities = 67/276 (24%), Positives = 110/276 (39%), Gaps = 11/276 (3%)
Query: 10 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
A + E +A D+ ++ L KV EE +EL+ + + E DLI + +L+
Sbjct: 80 AYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEA 139
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL-EAQQSADENNRMCK 128
L KE L+ +E L ++ + + K E G A+++L E + D NR+
Sbjct: 140 LLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQT 199
Query: 129 VLENRAQQDEERMDQL--TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA-EDRVKS 185
+ E Q ++L T + E RL+ D +GK E +LA EL ED+V+
Sbjct: 200 MKEELDFQKNIYSEELRETKRRHETRLVEID-NGKQREFESRLADALQELRAQHEDQVEQ 258
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKT 245
ELE K L + S E+ + V K
Sbjct: 259 YK---KELE---KTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQ 312
Query: 246 VKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ + ++ LED L +D + L E + AE+
Sbjct: 313 LAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEM 348
>AL135927-1|CAI15521.1| 572|Homo sapiens lamin A/C protein.
Length = 572
Score = 59.3 bits (137), Expect = 2e-08
Identities = 67/276 (24%), Positives = 110/276 (39%), Gaps = 11/276 (3%)
Query: 10 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
A + E +A D+ ++ L KV EE +EL+ + + E DLI + +L+
Sbjct: 80 AYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEA 139
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL-EAQQSADENNRMCK 128
L KE L+ +E L ++ + + K E G A+++L E + D NR+
Sbjct: 140 LLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQT 199
Query: 129 VLENRAQQDEERMDQL--TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA-EDRVKS 185
+ E Q ++L T + E RL+ D +GK E +LA EL ED+V+
Sbjct: 200 MKEELDFQKNIYSEELRETKRRHETRLVEID-NGKQREFESRLADALQELRAQHEDQVEQ 258
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKT 245
ELE K L + S E+ + V K
Sbjct: 259 YK---KELE---KTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQ 312
Query: 246 VKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ + ++ LED L +D + L E + AE+
Sbjct: 313 LAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEM 348
Score = 34.3 bits (75), Expect = 0.49
Identities = 51/223 (22%), Positives = 98/223 (43%), Gaps = 33/223 (14%)
Query: 1 MDAIKKKMQAMKLEK-DNAMDKAD-------TCEQQARDANLRAEKVNEEVRELQKKLAQ 52
++ KK+++ K DNA A+ ++ + + +R + ++ ++ +LQK+LA
Sbjct: 256 VEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAA 315
Query: 53 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
E L ++ + ++ + + L E E+A + ++QQ ++ Q+
Sbjct: 316 KEAKL---RDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY-----------QE 361
Query: 113 LLEAQQSAD-ENNRMCKVLENRAQQDEERM---DQLTNQLKEARLLAEDAD---GKSDEV 165
LL+ + + D E + K+LE +EER+ T+Q R + + G S
Sbjct: 362 LLDIKLALDMEIHAYRKLLEG----EEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTK 417
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
RKL E ++ SG + E++EE K V KS E
Sbjct: 418 KRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNE 460
>AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein.
Length = 1956
Score = 58.8 bits (136), Expect = 2e-08
Identities = 50/228 (21%), Positives = 109/228 (47%), Gaps = 33/228 (14%)
Query: 5 KKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KKK++A M+ E + + + E++A+ A + A ++EE+++ Q +A +E
Sbjct: 1749 KKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENM 1808
Query: 61 KNKLEQANKDLEEKEKQ-LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
+ + K L E E+ L + ++ L +V+++E +LE RS EAQ+
Sbjct: 1809 EQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSA-------EAQRG 1861
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
A R K L +A++D++ + ++ Q+ D++ K+ + ++EVA
Sbjct: 1862 ARRLERCIKELTYQAEEDKKNLSRMQTQM--------------DKLQLKVQNYKQQVEVA 1907
Query: 180 E-------DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
E + K +++E++E +V + + L++ + ++V+E
Sbjct: 1908 ETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAREFGKKVQE 1955
Score = 56.0 bits (129), Expect = 1e-07
Identities = 61/269 (22%), Positives = 118/269 (43%), Gaps = 24/269 (8%)
Query: 5 KKKMQAMKLEKDNAMD---KADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLILN 60
K +++ EKD ++ + C + ++L +E K EV L+KK+ EEDL
Sbjct: 1591 KAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKM---EEDLNEM 1647
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ---QIEEDLEK----SEERSGTAQQKL 113
+ +L AN+ + E K L + ++ L ++ Q+ DL++ +E R+ Q +L
Sbjct: 1648 ELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSEL 1707
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD--EVSRKLAF 171
+ + ++ R ++ E + ER++ Q LL++ ++D + ++
Sbjct: 1708 EDLRSLQEQTERGRRLSEEELLEATERINLFYTQ--NTSLLSQKKKLEADVARMQKEAEE 1765
Query: 172 VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXX 231
V E + AE++ K + + L EELK +++ LE + E Q + +
Sbjct: 1766 VVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDL------QKRL 1819
Query: 232 XXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
K ++KL+ V LE EL
Sbjct: 1820 AEAEQMALMGSRKQIQKLESRVRELEGEL 1848
Score = 54.0 bits (124), Expect = 6e-07
Identities = 41/212 (19%), Positives = 95/212 (44%), Gaps = 8/212 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
IK K+Q K+ + ++ + E+ + R K+ +E EL+K++ +E L+ ++ +
Sbjct: 931 IKSKIQLEARVKELS-ERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKE 989
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE-------DLEKSEERSGTAQQKLLEA 116
++ +++ +++ LNR + ++E DL EE+ + + L+
Sbjct: 990 KRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKL 1049
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
+Q DE + E + +L LK R E+ + ++ +L E EL
Sbjct: 1050 EQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELEL 1109
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
+V++ +++L++ +K + +K L+
Sbjct: 1110 SQMNSKVENEKGLVAQLQKTVKELQTQIKDLK 1141
Score = 47.6 bits (108), Expect = 5e-05
Identities = 49/212 (23%), Positives = 100/212 (47%), Gaps = 15/212 (7%)
Query: 12 KLEKDNAMDKADTCEQQARDANL-RAEKVNEEV----RELQKKLAQVEEDLILNKNKLEQ 66
K E+ A+ A E QA L + + EE L+++ ++E++ N++ +
Sbjct: 1481 KHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVRE 1540
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN-NR 125
K+L E EK E E + +++ E LE++E + Q +LLEA+ + +
Sbjct: 1541 GTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSE 1600
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD-EVSRKLAFVEDELEVAEDRVK 184
+ +EN ++ + +D L + L D++ KS EV+R +E++L E ++
Sbjct: 1601 KDEEIENFRRKQQCTIDSLQSSL--------DSEAKSRIEVTRLKKKMEEDLNEMELQLS 1652
Query: 185 SGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
+ ++SE + L + +K L++ + + Q
Sbjct: 1653 CANRQVSEATKSLGQLQIQIKDLQMQLDDSTQ 1684
Score = 44.4 bits (100), Expect = 5e-04
Identities = 47/230 (20%), Positives = 107/230 (46%), Gaps = 10/230 (4%)
Query: 1 MDAIKKKMQAMK---LEKDNAMDKADTCEQQAR--DANLRAEKVN--EEVRELQKKLAQV 53
+DA +K++QA+ L+ N +++ ++ R + NL+ E N +VRE K L ++
Sbjct: 1489 LDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEM 1548
Query: 54 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
E+ L + + + LEE E L E+++ ++ + + +LE+ +
Sbjct: 1549 EKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENF 1608
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERM-DQLTNQLKEARLLAEDADGKSDEVSRKLAFV 172
QQ ++ + E +++ + R+ ++ L E L A+ + E ++ L +
Sbjct: 1609 RRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQL 1668
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVV--GNSLKSLEVSEEKANQRVEE 220
+ +++ + ++ S+L+E++ V NSL E+ + ++ Q E
Sbjct: 1669 QIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTE 1718
Score = 44.0 bits (99), Expect = 6e-04
Identities = 41/240 (17%), Positives = 96/240 (40%), Gaps = 7/240 (2%)
Query: 49 KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 108
K ++V E++ K + Q K LE+ E Q +A+ +L ++ + L+ +E
Sbjct: 863 KSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLAN 922
Query: 109 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 168
+++ +S + K L R +++EE +LT + ++ + + D++
Sbjct: 923 VEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETM 982
Query: 169 LAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA-------NQRVEEF 221
L E E E +VK+ ++ L E++ + + K ++ + ++ +++
Sbjct: 983 LVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSL 1042
Query: 222 XXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
K ++E+ +LE L +N++ ++L EL
Sbjct: 1043 SKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEEL 1102
Score = 44.0 bits (99), Expect = 6e-04
Identities = 61/287 (21%), Positives = 119/287 (41%), Gaps = 32/287 (11%)
Query: 28 QARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT----EA 83
Q + A ++E EE++ Q L Q + DLIL ++ ++EE+ + L + EA
Sbjct: 880 QLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEA 939
Query: 84 EVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQ 143
V L+ +V++ EE + R + + E ++ D+ M E + E ++
Sbjct: 940 RVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKN 999
Query: 144 LT----------NQLKEARLLAEDA-----------DGKSDEVSR---KLAFVEDELEVA 179
LT ++L A + ++A + K +S+ KL DELE A
Sbjct: 1000 LTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGA 1059
Query: 180 EDRVKSG----DAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXX 235
++ + + ++ +LE LK+ S+++LE S+ + + +
Sbjct: 1060 LEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENE 1119
Query: 236 XXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
KTVK+LQ ++ L+++L + + E +LA
Sbjct: 1120 KGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLA 1166
Score = 42.3 bits (95), Expect = 0.002
Identities = 50/213 (23%), Positives = 92/213 (43%), Gaps = 22/213 (10%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDAN----LRAEKVNEEVRELQKKLAQVEEDLIL 59
++K ++LE D+ + + + + +A L E+++E +L K + Q+ DL
Sbjct: 1239 LEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDK-VTQLANDLAA 1297
Query: 60 NKNKLEQANKD----LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 115
K KL + + LEEKE + E + R+++ + LEK + +Q L
Sbjct: 1298 QKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETK----SQSALAH 1353
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
A Q A R C +L + ++++E +L L +++ AE + + + ED
Sbjct: 1354 ALQKA---QRDCDLLREQYEEEQEVKAELHRTL--SKVNAEMVQWRMKYENNVIQRTED- 1407
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
ED K ++ E E + V SLE
Sbjct: 1408 ---LEDAKKELAIRLQEAAEAMGVANARNASLE 1437
Score = 39.9 bits (89), Expect = 0.010
Identities = 44/222 (19%), Positives = 100/222 (45%), Gaps = 17/222 (7%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D ++ + + EK K ++ N K+N + +Q+ Q +DL +
Sbjct: 976 IDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHME 1035
Query: 61 KNK---LEQANKDLEEKEKQLT-ATEAE-VAALN--RKVQQIEEDLEKSEERSGTAQQKL 113
+ K L +AN LE++ +L A E E A +N R++ ++E +L+ + E +
Sbjct: 1036 EEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQ 1095
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD-EVSRKLAFV 172
+ + + ++ + ++ + QL +KE + +D K + E + +
Sbjct: 1096 RHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKME 1155
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVV-GNSLKSLEVSEEK 213
+ ++ +D +++L E L+ V G+SL LE+++++
Sbjct: 1156 RERADLTQD--------LADLNERLEEVGGSSLAQLEITKKQ 1189
Score = 39.9 bits (89), Expect = 0.010
Identities = 33/179 (18%), Positives = 81/179 (45%), Gaps = 8/179 (4%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
+++ ++++ D++ ++Q A R + E+ +L+ Q E L++ +L +
Sbjct: 1671 QIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLE 1730
Query: 67 ANKDLEEKEKQLTAT-------EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
A + + Q T+ EA+VA + ++ +++ ++ + +EE++ A + +
Sbjct: 1731 ATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEE 1790
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS-DEVSRKLAFVEDELE 177
+ LE + E+ + L +L EA +A K ++ ++ +E ELE
Sbjct: 1791 LKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELE 1849
Score = 39.1 bits (87), Expect = 0.017
Identities = 36/217 (16%), Positives = 99/217 (45%), Gaps = 14/217 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+KK++ ++ + + T E + ++ E +NE++ +L + V+E
Sbjct: 972 LKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQE-------A 1024
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+Q DL +E++L++ L ++V ++E LE+ + +++L + + + N
Sbjct: 1025 HQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLN 1084
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
+ LE+ + E + + +L + E+ G ++ + + ++ +++ ++++
Sbjct: 1085 RESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKL 1144
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
++ +++E E + L L N+R+EE
Sbjct: 1145 EAERTTRAKMERERADLTQDLADL-------NERLEE 1174
Score = 34.7 bits (76), Expect = 0.37
Identities = 41/224 (18%), Positives = 95/224 (42%), Gaps = 14/224 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN-------EEVRELQKKLAQVEED 56
+K+K++A + + + Q D N R E+V E ++ + K+ ++ D
Sbjct: 1140 LKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKIQKLHRD 1199
Query: 57 LILNKNKLEQANKDLEEKEKQ-LTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQQK 112
+ E + L+++ L E +V L + K+++ + DL+ + T ++
Sbjct: 1200 MEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQ 1259
Query: 113 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 172
+ A+ +A+ ++C + E R + ++D++T + +S E R+L
Sbjct: 1260 MTRAKANAE---KLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEK 1316
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
E + + +I +L +L+ S +L + +KA +
Sbjct: 1317 EALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQR 1360
>X98801-1|CAA67333.1| 1263|Homo sapiens dynactin protein.
Length = 1263
Score = 58.4 bits (135), Expect = 3e-08
Identities = 57/232 (24%), Positives = 106/232 (45%), Gaps = 17/232 (7%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANL---RAEKVNEEVRELQKKLAQVEEDLILNK 61
K+ ++A + + D AD E D + RAE + +EV L++++ ++ DL + K
Sbjct: 269 KEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILK 328
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ-QSA 120
++E+ D QL E + A L + ++ DL SE++ QKL+E + Q
Sbjct: 329 AEIEEKGSDGAASSYQLKQLEEQNARLKDALVRM-RDLSSSEKQEHVKLQKLMEKKNQEL 387
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE-------DADGKSDEVSRKLAFVE 173
+ + + L+ Q E +D+L Q+ +A L AE D + +E R+L
Sbjct: 388 EVVRQQRERLQEELSQAESTIDELKEQV-DAALGAEEMVEMLTDRNLNLEEKVRELRETV 446
Query: 174 DELEV---AEDRVKSGDAKIS-ELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
+LE D ++ + EL E+L + G ++ + E A + V ++
Sbjct: 447 GDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADY 498
Score = 43.6 bits (98), Expect = 8e-04
Identities = 47/215 (21%), Positives = 99/215 (46%), Gaps = 11/215 (5%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN-EEVRELQKKLAQVEEDLILNKNKLE 65
+ Q LE+ + E +A+ L K+ E+V+E + K+ + + DL + +L+
Sbjct: 206 RAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADL---QRRLK 262
Query: 66 QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
+A K+ +E + E+A ++ D E +EER+ + QQ++ ++ DE
Sbjct: 263 EARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTT 322
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
++L +A+ +E+ D + + +L ++A K D + R E ++ VK
Sbjct: 323 DLEIL--KAEIEEKGSDGAASSYQLKQLEEQNARLK-DALVRMRDLSSSE---KQEHVKL 376
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ + +EL+VV + L+ +A ++E
Sbjct: 377 -QKLMEKKNQELEVVRQQRERLQEELSQAESTIDE 410
Score = 43.6 bits (98), Expect = 8e-04
Identities = 43/229 (18%), Positives = 112/229 (48%), Gaps = 14/229 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++++++ + E A++ + ++ D E + +++ +++++ K +
Sbjct: 257 LQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKER 316
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED-------LEKSEERSGTAQQKLLEA 116
+++ DLE + ++ ++ AA + +++Q+EE L + + S + +Q+ ++
Sbjct: 317 VDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKL 376
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
Q+ ++ N+ +V+ + ++ +E + Q + + E + + A G ++E+ L L
Sbjct: 377 QKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALG-AEEMVEMLTDRNLNL 435
Query: 177 E--VAEDRVKSGDAK-ISELEEELKVVGNSLKSLEVSE--EKANQRVEE 220
E V E R GD + ++E+ +EL+ + LE+ E + A RV E
Sbjct: 436 EEKVRELRETVGDLEAMNEMNDELQENARETE-LELREQLDMAGARVRE 483
Score = 43.2 bits (97), Expect = 0.001
Identities = 35/208 (16%), Positives = 89/208 (42%)
Query: 69 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
+DLEEK + L AE A +++++ + LE+ +E Q++ + Q+ E + K
Sbjct: 210 RDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAK 269
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDA 188
++ E M + ++ A L E A+ +++ + +++ +++ ++ ++ A
Sbjct: 270 EALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKA 329
Query: 189 KISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKK 248
+I E + LK LE + + + ++
Sbjct: 330 EIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEV 389
Query: 249 LQKEVDRLEDELGINKDRYKSLADEMDS 276
++++ +RL++EL + L +++D+
Sbjct: 390 VRQQRERLQEELSQAESTIDELKEQVDA 417
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/143 (23%), Positives = 67/143 (46%), Gaps = 4/143 (2%)
Query: 78 LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQD 137
L + E L +V+ +EE LE + + KL E ++ ++ +V E +++
Sbjct: 195 LPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEK---HKIQLEQVQEWKSKMQ 251
Query: 138 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 197
E++ D L +LKEAR A++A + ++A D +E+A + + + L++E+
Sbjct: 252 EQQAD-LQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEV 310
Query: 198 KVVGNSLKSLEVSEEKANQRVEE 220
+ + + L E +EE
Sbjct: 311 EALKERVDELTTDLEILKAEIEE 333
Score = 35.1 bits (77), Expect = 0.28
Identities = 32/152 (21%), Positives = 71/152 (46%), Gaps = 15/152 (9%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
K+Q + +K+ ++ ++ ++ +AE +E++E Q A E+++ L
Sbjct: 375 KLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKE-QVDAALGAEEMV---EMLTD 430
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE-----------ERSGTAQQKLLE 115
N +LEEK ++L T ++ A+N +++E+ ++E R AQ+++
Sbjct: 431 RNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEA 490
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQ 147
AQ++ + + K ++ +LTNQ
Sbjct: 491 AQETVADYQQTIKKYRQLTAHLQDVNRELTNQ 522
Score = 32.7 bits (71), Expect = 1.5
Identities = 31/139 (22%), Positives = 63/139 (45%), Gaps = 11/139 (7%)
Query: 57 LILNKNKL----EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
LI NKL ++ D E + E AAL ++ E K E+R ++
Sbjct: 881 LISTMNKLATAMQEGEYDAERPPSKPPPVELRAAALRAEITDAEGLGLKLEDRETVIKEL 940
Query: 113 L----LEAQQSADENNRMC---KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 165
++ ++ ++ N R+ K L++ A+ +ER++++ +L+E + L + + +E
Sbjct: 941 KKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLRKKEKEFEET 1000
Query: 166 SRKLAFVEDELEVAEDRVK 184
L D+LE + +K
Sbjct: 1001 MDALQADIDQLEAEKAELK 1019
Score = 32.7 bits (71), Expect = 1.5
Identities = 26/105 (24%), Positives = 49/105 (46%), Gaps = 8/105 (7%)
Query: 29 ARDANLRAEKVNEEVRELQK-------KLAQVEEDLILNKNKLEQANKDLEEK-EKQLTA 80
A L+ E ++EL+K +L++ L L + KL+ A KD +E+ EK T
Sbjct: 923 AEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTR 982
Query: 81 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
E A L +K ++ EE ++ + + + E +Q + ++
Sbjct: 983 LEETQALLRKKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSK 1027
>X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein.
Length = 1411
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/223 (20%), Positives = 99/223 (44%), Gaps = 8/223 (3%)
Query: 5 KKKMQAMKLEKD----NAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KK +QA +KD + E ++ + E ++L+++L++VE
Sbjct: 332 KKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHL 391
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS----EERSGTAQQKLLEA 116
K + +Q + EEKE+ ++E+ L+ K+ + E L ++ +E+ + +KL++
Sbjct: 392 KAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDK 451
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
+Q + LE + ++ +L +QL + + ++ + KL +++L
Sbjct: 452 EQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDL 511
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
E ++ D KI LE L+ ++ LE E +++
Sbjct: 512 EQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQ 554
Score = 55.2 bits (127), Expect = 2e-07
Identities = 47/215 (21%), Positives = 101/215 (46%), Gaps = 15/215 (6%)
Query: 16 DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKE 75
D A + +Q+ + ++V ++++ Q+ +Q+E L K K + EE E
Sbjct: 670 DTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELE 729
Query: 76 KQLTATEAEVAALNRKVQQIEEDLEKSE------ERSGTAQQKLLEAQQSADENNRMCKV 129
Q+ EA+ + +Q +DL++ E T K LE ++ + R+
Sbjct: 730 GQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRL--D 787
Query: 130 LENRAQQDEERMDQLTNQLKEARLLAEDADGKS-------DEVSRKLAFVEDELEVAEDR 182
L+ +++ E +LT Q +E ++L +D + S +E++ ++ EL+ +
Sbjct: 788 LQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKME 847
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 217
++ ++S ++++L V +SLK+ + EK NQ+
Sbjct: 848 KEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQK 882
Score = 53.6 bits (123), Expect = 8e-07
Identities = 44/213 (20%), Positives = 101/213 (47%), Gaps = 11/213 (5%)
Query: 19 MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQL 78
+D TC++ ++ E +E +EL+K L + +E K +L + L + + L
Sbjct: 888 LDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTL 947
Query: 79 TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL-LEAQQSADENNRMCKVLENRAQQ- 136
E E L + ++++ E+ +++ Q +L + Q + N++ + L AQ+
Sbjct: 948 KQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQEL 1007
Query: 137 --DEERMDQLTNQLKEA----RLLAEDADGKSDEV---SRKLAFVEDELEVAEDRVKSGD 187
++E++ L N +++ + L D G+ E+ + L VE++L +A++ + S
Sbjct: 1008 AAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNR 1067
Query: 188 AKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+I + ++ + + +LE K Q+++E
Sbjct: 1068 NQIGNQNKLIQELKTAKATLEQDSAKKEQQLQE 1100
Score = 51.2 bits (117), Expect = 4e-06
Identities = 35/184 (19%), Positives = 79/184 (42%)
Query: 15 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 74
K ++ K E + + + E +LQ++L Q ++L K K+ + E+
Sbjct: 965 KQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKS 1024
Query: 75 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRA 134
++ +++ ++ +DL+ EE+ AQ+ L+ + N++ + L+
Sbjct: 1025 QETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAK 1084
Query: 135 QQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 194
E+ + QL+E +D + ++L + +L E+ + +I++L
Sbjct: 1085 ATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLN 1144
Query: 195 EELK 198
EELK
Sbjct: 1145 EELK 1148
Score = 48.4 bits (110), Expect = 3e-05
Identities = 53/274 (19%), Positives = 121/274 (44%), Gaps = 12/274 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+++IK+K+ + EK +T Q+ + ++ E++N ++ +L +V+ +
Sbjct: 795 LESIKQKLTKQEEEKQILKQDFETLSQETK---IQHEELNNRIQTTVTELQKVKMEKEAL 851
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+L L + L +++E N+K + DLEK+ + Q ++ + +
Sbjct: 852 MTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKE--LKHQLQVQMENTL 909
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
E + K LE + + +L N ++E + A++ ++++ ++L +EL+ +
Sbjct: 910 KEQKELKKSLEKEKEASHQLKLEL-NSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSS 968
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
++ K +I L+ ELK+ L+ E+ E K Q++ +
Sbjct: 969 EQKKK---QIEALQGELKIA--VLQKTEL-ENKLQQQLTQAAQELAAEKEKISVLQNNYE 1022
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
+T K+LQ + E EL + KS+ +++
Sbjct: 1023 KSQETFKQLQSDFYGRESELLATRQDLKSVEEKL 1056
Score = 47.2 bits (107), Expect = 7e-05
Identities = 50/214 (23%), Positives = 93/214 (43%), Gaps = 12/214 (5%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL-ILNKNKLEQ 66
MQ ++ N + + + EQQ + N+ K + E ++ Q + Q E + +L K +LE
Sbjct: 936 MQEQLIQAQNTLKQNEKEEQQLQ-GNINELKQSSEQKKKQIEALQGELKIAVLQKTELE- 993
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
NK ++QLT E+AA K+ ++ + EKS+E Q + +
Sbjct: 994 -NK----LQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQD 1048
Query: 127 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS- 185
K +E + +E + NQ+ L ++ + + A E +L ++R K+
Sbjct: 1049 LKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQL---QERCKAL 1105
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
D + + +E ++V K E+ E K Q E
Sbjct: 1106 QDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKE 1139
Score = 46.8 bits (106), Expect = 9e-05
Identities = 45/217 (20%), Positives = 94/217 (43%), Gaps = 11/217 (5%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEK---VNEEVRELQKKLAQVEEDLILNK 61
K+ + ++ E+++ K E + N EK + E+V +L +KL E +K
Sbjct: 536 KENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSES---HK 592
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
E + ++E++ L A + V +L V ++ L +S+E+ ++ +A+
Sbjct: 593 QAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQI-KAKTELL 651
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
+ K + Q+ +D N L++ + + D+V+ KL ++ E
Sbjct: 652 LSAEAAKTAQRADLQNH--LDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLES 709
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVS--EEKANQ 216
+K K LE++ + + +K LE E KA++
Sbjct: 710 HLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASK 746
Score = 46.4 bits (105), Expect = 1e-04
Identities = 48/282 (17%), Positives = 116/282 (41%), Gaps = 9/282 (3%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKV---NEEVRELQKKLAQVEEDLILNKNK 63
++ + LE + + +A ++ R L +EK+ ++V +LQ KL+++EE L
Sbjct: 418 QLHSKLLETERQLGEAHGRLKEQRQ--LSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTN 475
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ L++ ++Q +A + K+++ + DLE+ + G QK+ + ++
Sbjct: 476 STELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKS 535
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
+LE + ++ + L E ++V++ ++++ E +
Sbjct: 536 KENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQ 595
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF--XXXXXXXXXXXXXXXXXXXX 241
++ ++ E + L+ + + SLE S + N ++ E
Sbjct: 596 ENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAE 655
Query: 242 XXKTVKK--LQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
KT ++ LQ +D ++ L + + ++D A+L
Sbjct: 656 AAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKL 697
Score = 44.4 bits (100), Expect = 5e-04
Identities = 36/192 (18%), Positives = 86/192 (44%), Gaps = 7/192 (3%)
Query: 36 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI 95
+EK+ +E ++LQ + A E + +++L + +++ ++L ++ V L +K Q +
Sbjct: 248 SEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTL 307
Query: 96 -------EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL 148
E+D K EE+ Q + + + C+ L++R E + ++ +L
Sbjct: 308 TENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVEL 367
Query: 149 KEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
E + + EV K ++ E + + + + + +L+ E+ + + L E
Sbjct: 368 SEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETE 427
Query: 209 VSEEKANQRVEE 220
+A+ R++E
Sbjct: 428 RQLGEAHGRLKE 439
Score = 43.6 bits (98), Expect = 8e-04
Identities = 37/166 (22%), Positives = 73/166 (43%), Gaps = 11/166 (6%)
Query: 5 KKKMQAMKLEKDNAMDKADTC-EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
K+ + KLE D EQ+ R+ + ++V +E EL+K+ + E L
Sbjct: 1165 KQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKL------ 1218
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ +++EKE + E A L ++ + E+L ++ ++Q+++ E ++ D+
Sbjct: 1219 ----HSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDL 1274
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
VLE Q +++ L + + E K E+ RKL
Sbjct: 1275 RGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKL 1320
Score = 43.2 bits (97), Expect = 0.001
Identities = 54/285 (18%), Positives = 117/285 (41%), Gaps = 11/285 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ A + + + +E + +++ + + + + E ++LQ++ + E+ +
Sbjct: 353 LSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQL 412
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL--LEAQ- 117
++++ Q + L E E+QL EA L + Q E L E++ Q KL LE Q
Sbjct: 413 QSEINQLHSKLLETERQL--GEAH-GRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQL 469
Query: 118 -QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
+ + + L+ QQ +E+ Q Q A+L +A ++V R++ + ++
Sbjct: 470 KEKVTNSTELQHQLDKTKQQHQEQ--QALQQSTTAKL--REAQNDLEQVLRQIGDKDQKI 525
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXX 236
+ E ++ IS LE+E + + +++ E NQ E+
Sbjct: 526 QNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLK 585
Query: 237 XXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ + L +V + L +DR SL ++ ++L
Sbjct: 586 NQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQL 630
Score = 42.3 bits (95), Expect = 0.002
Identities = 34/189 (17%), Positives = 81/189 (42%), Gaps = 4/189 (2%)
Query: 28 QARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAA 87
Q D + +++ Q++L ++ L KL+ + + E L + + +
Sbjct: 661 QRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLS 720
Query: 88 LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQ 147
L +K +++E ++K E S + +A Q + ++ LE RA + ++++
Sbjct: 721 LEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEI 780
Query: 148 LKEARLLAEDADGKSDEVSRKLAFVEDELEVAED--RVKSGDAKI--SELEEELKVVGNS 203
+ RL + + + +KL E+E ++ + S + KI EL ++
Sbjct: 781 VSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTE 840
Query: 204 LKSLEVSEE 212
L+ +++ +E
Sbjct: 841 LQKVKMEKE 849
Score = 41.5 bits (93), Expect = 0.003
Identities = 45/225 (20%), Positives = 96/225 (42%), Gaps = 12/225 (5%)
Query: 6 KKMQAMKLE----KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
KK++A LE K+ A+ Q D LRA ++++++ ++ ++ DL
Sbjct: 733 KKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKS 792
Query: 62 NKLEQANKDL--EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL-LEAQQ 118
LE + L +E+EKQ+ + E + K+Q E+L + + T QK+ +E +
Sbjct: 793 EALESIKQKLTKQEEEKQILKQDFETLSQETKIQ--HEELNNRIQTTVTELQKVKMEKEA 850
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
E + + L + + + + ++ + D + E+ +L +
Sbjct: 851 LMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLK 910
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE---KANQRVEE 220
+ +K K E +LK+ NS++ + + K N++ E+
Sbjct: 911 EQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQ 955
Score = 40.7 bits (91), Expect = 0.006
Identities = 35/231 (15%), Positives = 105/231 (45%), Gaps = 11/231 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ ++++++ + D +QQ ++ + ++RE Q L QV +
Sbjct: 462 LSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDK 521
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED---LEKSEERSGTAQQ---KLL 114
K++ L++ ++ ++ E E L K+Q E + L + +E++ T Q+ +L
Sbjct: 522 DQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLT 581
Query: 115 EAQQSADENNRMCKV-LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
E ++ E+++ + L ++ Q+ + + +++ + + + +E K++ ++
Sbjct: 582 EKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLD 641
Query: 174 DELEVAEDRVKSGD----AKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+++ + + S + A+ ++L+ L N+L+ + K ++++
Sbjct: 642 IQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQ 692
Score = 34.3 bits (75), Expect = 0.49
Identities = 34/195 (17%), Positives = 86/195 (44%), Gaps = 8/195 (4%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
EQQ +A + + ++K AQ+ ++ K+K ++ E E+++T E
Sbjct: 141 EQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEE- 199
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
LN++ I++ + +R G +L+ E ++ +++N + E ++L
Sbjct: 200 --LNKEATVIQDLKTELLQRPGIEDVAVLK-----KELVQVQTLMDNMTLERERESEKLK 252
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
++ K+ + ++ ++ +LA E+ V ++ + ++EL ++ + + +L
Sbjct: 253 DECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLL 312
Query: 206 SLEVSEEKANQRVEE 220
E K ++ E
Sbjct: 313 KKEQDYTKLEEKHNE 327
>L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated protein
protein.
Length = 1410
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/223 (20%), Positives = 99/223 (44%), Gaps = 8/223 (3%)
Query: 5 KKKMQAMKLEKD----NAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
KK +QA +KD + E ++ + E ++L+++L++VE
Sbjct: 332 KKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHL 391
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS----EERSGTAQQKLLEA 116
K + +Q + EEKE+ ++E+ L+ K+ + E L ++ +E+ + +KL++
Sbjct: 392 KAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDK 451
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
+Q + LE + ++ +L +QL + + ++ + KL +++L
Sbjct: 452 EQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDL 511
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
E ++ D KI LE L+ ++ LE E +++
Sbjct: 512 EQVLRQIGEKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQ 554
Score = 54.4 bits (125), Expect = 4e-07
Identities = 47/215 (21%), Positives = 100/215 (46%), Gaps = 15/215 (6%)
Query: 16 DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKE 75
D A + Q+ + ++V ++++ Q+ +Q+E L K K + EE E
Sbjct: 670 DTAQNALQDKHQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELE 729
Query: 76 KQLTATEAEVAALNRKVQQIEEDLEKSE------ERSGTAQQKLLEAQQSADENNRMCKV 129
Q+ EA+ + +Q +DL++ E T K LE ++ + R+
Sbjct: 730 GQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRL--D 787
Query: 130 LENRAQQDEERMDQLTNQLKEARLLAEDADGKS-------DEVSRKLAFVEDELEVAEDR 182
L+ +++ E +LT Q +E ++L +D + S +E++ ++ EL+ +
Sbjct: 788 LQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKME 847
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 217
++ ++S ++++L V +SLK+ + EK NQ+
Sbjct: 848 KEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQK 882
Score = 53.6 bits (123), Expect = 8e-07
Identities = 44/213 (20%), Positives = 101/213 (47%), Gaps = 11/213 (5%)
Query: 19 MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQL 78
+D TC++ ++ E +E +EL+K L + +E K +L + L + + L
Sbjct: 888 LDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTL 947
Query: 79 TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL-LEAQQSADENNRMCKVLENRAQQ- 136
E E L + ++++ E+ +++ Q +L + Q + N++ + L AQ+
Sbjct: 948 KQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQEL 1007
Query: 137 --DEERMDQLTNQLKEA----RLLAEDADGKSDEV---SRKLAFVEDELEVAEDRVKSGD 187
++E++ L N +++ + L D G+ E+ + L VE++L +A++ + S
Sbjct: 1008 AAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNR 1067
Query: 188 AKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+I + ++ + + +LE K Q+++E
Sbjct: 1068 NQIGNQNKLIQELKTAKATLEQDSAKKEQQLQE 1100
Score = 51.2 bits (117), Expect = 4e-06
Identities = 35/184 (19%), Positives = 79/184 (42%)
Query: 15 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 74
K ++ K E + + + E +LQ++L Q ++L K K+ + E+
Sbjct: 965 KQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKS 1024
Query: 75 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRA 134
++ +++ ++ +DL+ EE+ AQ+ L+ + N++ + L+
Sbjct: 1025 QETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAK 1084
Query: 135 QQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELE 194
E+ + QL+E +D + ++L + +L E+ + +I++L
Sbjct: 1085 ATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLN 1144
Query: 195 EELK 198
EELK
Sbjct: 1145 EELK 1148
Score = 49.6 bits (113), Expect = 1e-05
Identities = 51/282 (18%), Positives = 115/282 (40%), Gaps = 9/282 (3%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKV---NEEVRELQKKLAQVEEDLILNKNK 63
++ + LE + + +A ++ R L +EK+ ++V +LQ KL+++EE L
Sbjct: 418 QLHSKLLETERQLGEAHGRLKEQRQ--LSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTN 475
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ L++ ++Q +A + K+++ + DLE+ + G QK+ + ++
Sbjct: 476 STELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGEKDQKIQNLEALLQKS 535
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
+LE + ++ + L E DEV++ V+++ E +
Sbjct: 536 KENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQDEVTQLTENVKNQSESHKQAQ 595
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF--XXXXXXXXXXXXXXXXXXXX 241
++ ++ E + L+ + + SLE S + N ++ E
Sbjct: 596 ENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAE 655
Query: 242 XXKTVKK--LQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
KT ++ LQ +D ++ L + ++D A+L
Sbjct: 656 AAKTAQRADLQNHLDTAQNALQDKHQELNKITTQLDQVTAKL 697
Score = 48.4 bits (110), Expect = 3e-05
Identities = 53/274 (19%), Positives = 121/274 (44%), Gaps = 12/274 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+++IK+K+ + EK +T Q+ + ++ E++N ++ +L +V+ +
Sbjct: 795 LESIKQKLTKQEEEKQILKQDFETLSQETK---IQHEELNNRIQTTVTELQKVKMEKEAL 851
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+L L + L +++E N+K + DLEK+ + Q ++ + +
Sbjct: 852 MTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKE--LKHQLQVQMENTL 909
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
E + K LE + + +L N ++E + A++ ++++ ++L +EL+ +
Sbjct: 910 KEQKELKKSLEKEKEASHQLKLEL-NSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSS 968
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXX 240
++ K +I L+ ELK+ L+ E+ E K Q++ +
Sbjct: 969 EQKKK---QIEALQGELKIA--VLQKTEL-ENKLQQQLTQAAQELAAEKEKISVLQNNYE 1022
Query: 241 XXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
+T K+LQ + E EL + KS+ +++
Sbjct: 1023 KSQETFKQLQSDFYGRESELLATRQDLKSVEEKL 1056
Score = 47.2 bits (107), Expect = 7e-05
Identities = 50/214 (23%), Positives = 93/214 (43%), Gaps = 12/214 (5%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL-ILNKNKLEQ 66
MQ ++ N + + + EQQ + N+ K + E ++ Q + Q E + +L K +LE
Sbjct: 936 MQEQLIQAQNTLKQNEKEEQQLQ-GNINELKQSSEQKKKQIEALQGELKIAVLQKTELE- 993
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
NK ++QLT E+AA K+ ++ + EKS+E Q + +
Sbjct: 994 -NK----LQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQD 1048
Query: 127 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS- 185
K +E + +E + NQ+ L ++ + + A E +L ++R K+
Sbjct: 1049 LKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQL---QERCKAL 1105
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
D + + +E ++V K E+ E K Q E
Sbjct: 1106 QDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKE 1139
Score = 43.6 bits (98), Expect = 8e-04
Identities = 37/166 (22%), Positives = 73/166 (43%), Gaps = 11/166 (6%)
Query: 5 KKKMQAMKLEKDNAMDKADTC-EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
K+ + KLE D EQ+ R+ + ++V +E EL+K+ + E L
Sbjct: 1165 KQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKL------ 1218
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ +++EKE + E A L ++ + E+L ++ ++Q+++ E ++ D+
Sbjct: 1219 ----HSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDL 1274
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
VLE Q +++ L + + E K E+ RKL
Sbjct: 1275 RGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKL 1320
Score = 43.2 bits (97), Expect = 0.001
Identities = 54/285 (18%), Positives = 117/285 (41%), Gaps = 11/285 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ A + + + +E + +++ + + + + E ++LQ++ + E+ +
Sbjct: 353 LSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQL 412
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL--LEAQ- 117
++++ Q + L E E+QL EA L + Q E L E++ Q KL LE Q
Sbjct: 413 QSEINQLHSKLLETERQL--GEAH-GRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQL 469
Query: 118 -QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
+ + + L+ QQ +E+ Q Q A+L +A ++V R++ + ++
Sbjct: 470 KEKVTNSTELQHQLDKTKQQHQEQ--QALQQSTTAKL--REAQNDLEQVLRQIGEKDQKI 525
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXX 236
+ E ++ IS LE+E + + +++ E NQ E+
Sbjct: 526 QNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQDEVTQLTENVK 585
Query: 237 XXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ + L +V + L +DR SL ++ ++L
Sbjct: 586 NQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQL 630
Score = 43.2 bits (97), Expect = 0.001
Identities = 41/214 (19%), Positives = 89/214 (41%), Gaps = 5/214 (2%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
K+ + ++ E+++ K E + N EK + E+ + V+ +K
Sbjct: 536 KENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQDEVTQLTENVKNQSESHKQAQ 595
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
E + ++E++ L A + V +L V ++ L +S+E+ ++ +A+ +
Sbjct: 596 ENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQI-KAKTELLLSA 654
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
K + Q+ +D N L++ + D+V+ KL ++ E +K
Sbjct: 655 EAAKTAQRADLQNH--LDTAQNALQDKHQELNKITTQLDQVTAKLQDKQEHCSQLESHLK 712
Query: 185 SGDAKISELEEELKVVGNSLKSLEVS--EEKANQ 216
K LE++ + + +K LE E KA++
Sbjct: 713 EYKEKYLSLEQKTEELEGQIKKLEADSLEVKASK 746
Score = 41.9 bits (94), Expect = 0.002
Identities = 34/192 (17%), Positives = 85/192 (44%), Gaps = 7/192 (3%)
Query: 36 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI 95
+EK+ +E ++ + + A E + +++L + +++ ++L ++ V L +K Q +
Sbjct: 248 SEKLKDESKKFESQYASSEATISQLRSELSKGPQEVRVYVQELQKLKSSVNELTQKNQTL 307
Query: 96 -------EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL 148
E+D K EE+ Q + + + C+ L++R E + ++ +L
Sbjct: 308 TENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVEL 367
Query: 149 KEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
E + + EV K ++ E + + + + + +L+ E+ + + L E
Sbjct: 368 SEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETE 427
Query: 209 VSEEKANQRVEE 220
+A+ R++E
Sbjct: 428 RQLGEAHGRLKE 439
Score = 41.5 bits (93), Expect = 0.003
Identities = 45/225 (20%), Positives = 96/225 (42%), Gaps = 12/225 (5%)
Query: 6 KKMQAMKLE----KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
KK++A LE K+ A+ Q D LRA ++++++ ++ ++ DL
Sbjct: 733 KKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKS 792
Query: 62 NKLEQANKDL--EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL-LEAQQ 118
LE + L +E+EKQ+ + E + K+Q E+L + + T QK+ +E +
Sbjct: 793 EALESIKQKLTKQEEEKQILKQDFETLSQETKIQ--HEELNNRIQTTVTELQKVKMEKEA 850
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
E + + L + + + + ++ + D + E+ +L +
Sbjct: 851 LMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLK 910
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE---KANQRVEE 220
+ +K K E +LK+ NS++ + + K N++ E+
Sbjct: 911 EQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQ 955
Score = 40.3 bits (90), Expect = 0.007
Identities = 33/189 (17%), Positives = 80/189 (42%), Gaps = 4/189 (2%)
Query: 28 QARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAA 87
Q D + +++ ++L ++ L KL+ + + E L + + +
Sbjct: 661 QRADLQNHLDTAQNALQDKHQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLS 720
Query: 88 LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQ 147
L +K +++E ++K E S + +A Q + ++ LE RA + ++++
Sbjct: 721 LEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEI 780
Query: 148 LKEARLLAEDADGKSDEVSRKLAFVEDELEVAED--RVKSGDAKI--SELEEELKVVGNS 203
+ RL + + + +KL E+E ++ + S + KI EL ++
Sbjct: 781 VSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTE 840
Query: 204 LKSLEVSEE 212
L+ +++ +E
Sbjct: 841 LQKVKMEKE 849
Score = 39.1 bits (87), Expect = 0.017
Identities = 34/200 (17%), Positives = 88/200 (44%), Gaps = 13/200 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ ++++++ + D +QQ ++ + ++RE Q L QV +
Sbjct: 462 LSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGEK 521
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED---LEKSEERSGTAQQKLLEAQ 117
K++ L++ ++ ++ E E L K+Q E + L + +E++ T Q
Sbjct: 522 DQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQ------- 574
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
DE ++ + ++N+++ ++ + L +Q++E + A + + + + +L
Sbjct: 575 ---DEVTQLTENVKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLN 631
Query: 178 VAEDRVKSGDAKISELEEEL 197
++++V D +I E L
Sbjct: 632 ESKEKVSQLDIQIKAKTELL 651
Score = 32.3 bits (70), Expect = 2.0
Identities = 33/195 (16%), Positives = 85/195 (43%), Gaps = 8/195 (4%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
EQQ +A + + ++K AQ+ ++ K+K ++ E E+++T E
Sbjct: 141 EQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEE- 199
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
LN++ I++ + +R G +L+ E ++ +++N + E ++L
Sbjct: 200 --LNKEATVIQDLKTELLQRPGIEDVAVLK-----KELVQVQTLMDNMTLERERESEKLK 252
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
++ K+ ++ ++ +L+ E+ V ++ + ++EL ++ + + +L
Sbjct: 253 DESKKFESQYASSEATISQLRSELSKGPQEVRVYVQELQKLKSSVNELTQKNQTLTENLL 312
Query: 206 SLEVSEEKANQRVEE 220
E K ++ E
Sbjct: 313 KKEQDYTKLEEKHNE 327
>BC071583-1|AAH71583.1| 1139|Homo sapiens DCTN1 protein protein.
Length = 1139
Score = 58.4 bits (135), Expect = 3e-08
Identities = 57/232 (24%), Positives = 106/232 (45%), Gaps = 17/232 (7%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANL---RAEKVNEEVRELQKKLAQVEEDLILNK 61
K+ ++A + + D AD E D + RAE + +EV L++++ ++ DL + K
Sbjct: 150 KEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILK 209
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ-QSA 120
++E+ D QL E + A L + ++ DL SE++ QKL+E + Q
Sbjct: 210 AEIEEKGSDGAASSYQLKQLEEQNARLKDALVRM-RDLSSSEKQEHVKLQKLMEKKNQEL 268
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE-------DADGKSDEVSRKLAFVE 173
+ + + L+ Q E +D+L Q+ +A L AE D + +E R+L
Sbjct: 269 EVVRQQRERLQEELSQAESTIDELKEQV-DAALGAEEMVEMLTDRNLNLEEKVRELRETV 327
Query: 174 DELEV---AEDRVKSGDAKIS-ELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
+LE D ++ + EL E+L + G ++ + E A + V ++
Sbjct: 328 GDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADY 379
Score = 43.6 bits (98), Expect = 8e-04
Identities = 47/215 (21%), Positives = 99/215 (46%), Gaps = 11/215 (5%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN-EEVRELQKKLAQVEEDLILNKNKLE 65
+ Q LE+ + E +A+ L K+ E+V+E + K+ + + DL + +L+
Sbjct: 87 RAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADL---QRRLK 143
Query: 66 QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
+A K+ +E + E+A ++ D E +EER+ + QQ++ ++ DE
Sbjct: 144 EARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTT 203
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
++L +A+ +E+ D + + +L ++A K D + R E ++ VK
Sbjct: 204 DLEIL--KAEIEEKGSDGAASSYQLKQLEEQNARLK-DALVRMRDLSSSE---KQEHVKL 257
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ + +EL+VV + L+ +A ++E
Sbjct: 258 -QKLMEKKNQELEVVRQQRERLQEELSQAESTIDE 291
Score = 43.6 bits (98), Expect = 8e-04
Identities = 43/229 (18%), Positives = 112/229 (48%), Gaps = 14/229 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++++++ + E A++ + ++ D E + +++ +++++ K +
Sbjct: 138 LQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKER 197
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED-------LEKSEERSGTAQQKLLEA 116
+++ DLE + ++ ++ AA + +++Q+EE L + + S + +Q+ ++
Sbjct: 198 VDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKL 257
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
Q+ ++ N+ +V+ + ++ +E + Q + + E + + A G ++E+ L L
Sbjct: 258 QKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALG-AEEMVEMLTDRNLNL 316
Query: 177 E--VAEDRVKSGDAK-ISELEEELKVVGNSLKSLEVSE--EKANQRVEE 220
E V E R GD + ++E+ +EL+ + LE+ E + A RV E
Sbjct: 317 EEKVRELRETVGDLEAMNEMNDELQENARETE-LELREQLDMAGARVRE 364
Score = 43.2 bits (97), Expect = 0.001
Identities = 35/208 (16%), Positives = 89/208 (42%)
Query: 69 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
+DLEEK + L AE A +++++ + LE+ +E Q++ + Q+ E + K
Sbjct: 91 RDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAK 150
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDA 188
++ E M + ++ A L E A+ +++ + +++ +++ ++ ++ A
Sbjct: 151 EALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKA 210
Query: 189 KISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKK 248
+I E + LK LE + + + ++
Sbjct: 211 EIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEV 270
Query: 249 LQKEVDRLEDELGINKDRYKSLADEMDS 276
++++ +RL++EL + L +++D+
Sbjct: 271 VRQQRERLQEELSQAESTIDELKEQVDA 298
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/143 (23%), Positives = 67/143 (46%), Gaps = 4/143 (2%)
Query: 78 LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQD 137
L + E L +V+ +EE LE + + KL E ++ ++ +V E +++
Sbjct: 76 LPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEK---HKIQLEQVQEWKSKMQ 132
Query: 138 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 197
E++ D L +LKEAR A++A + ++A D +E+A + + + L++E+
Sbjct: 133 EQQAD-LQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEV 191
Query: 198 KVVGNSLKSLEVSEEKANQRVEE 220
+ + + L E +EE
Sbjct: 192 EALKERVDELTTDLEILKAEIEE 214
Score = 35.1 bits (77), Expect = 0.28
Identities = 32/152 (21%), Positives = 71/152 (46%), Gaps = 15/152 (9%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
K+Q + +K+ ++ ++ ++ +AE +E++E Q A E+++ L
Sbjct: 256 KLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKE-QVDAALGAEEMV---EMLTD 311
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE-----------ERSGTAQQKLLE 115
N +LEEK ++L T ++ A+N +++E+ ++E R AQ+++
Sbjct: 312 RNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEA 371
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQ 147
AQ++ + + K ++ +LTNQ
Sbjct: 372 AQETVADYQQTIKKYRQLTANLQDVNRELTNQ 403
Score = 32.7 bits (71), Expect = 1.5
Identities = 31/139 (22%), Positives = 63/139 (45%), Gaps = 11/139 (7%)
Query: 57 LILNKNKL----EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
LI NKL ++ D E + E AAL ++ E K E+R ++
Sbjct: 762 LISTMNKLATAMQEGEYDAERPPSKPPPVELRAAALRAEITDAEGLGLKLEDRETVIKEL 821
Query: 113 L----LEAQQSADENNRMC---KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 165
++ ++ ++ N R+ K L++ A+ +ER++++ +L+E + L + + +E
Sbjct: 822 KKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLRKKEKEFEET 881
Query: 166 SRKLAFVEDELEVAEDRVK 184
L D+LE + +K
Sbjct: 882 MDALQADIDQLEAEKAELK 900
Score = 32.7 bits (71), Expect = 1.5
Identities = 26/105 (24%), Positives = 49/105 (46%), Gaps = 8/105 (7%)
Query: 29 ARDANLRAEKVNEEVRELQK-------KLAQVEEDLILNKNKLEQANKDLEEK-EKQLTA 80
A L+ E ++EL+K +L++ L L + KL+ A KD +E+ EK T
Sbjct: 804 AEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTR 863
Query: 81 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
E A L +K ++ EE ++ + + + E +Q + ++
Sbjct: 864 LEETQALLRKKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSK 908
>BC068006-1|AAH68006.1| 627|Homo sapiens ERC1 protein protein.
Length = 627
Score = 58.4 bits (135), Expect = 3e-08
Identities = 40/239 (16%), Positives = 105/239 (43%), Gaps = 7/239 (2%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
E + ++ +++ L +EE++ + K+ + ++ EE+ KQ+ + + K+ Q++
Sbjct: 385 EMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVK 444
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
++L + + Q KL ++ + +VL+ E+R L ++ RL E
Sbjct: 445 QELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE 504
Query: 157 DADGKSDEVSRKLAFVED-------ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 209
+ + ++ ++++ + + E+ +D + + K++ L+++++ + L+ E
Sbjct: 505 EKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEK 564
Query: 210 SEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYK 268
+RV+ +T+++L+++ DR E E D YK
Sbjct: 565 QMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYK 623
Score = 44.0 bits (99), Expect = 6e-04
Identities = 44/287 (15%), Positives = 128/287 (44%), Gaps = 21/287 (7%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRAEKVNEEVRELQKKLAQVEEDLIL 59
++IKK ++ ++ + +A + E+ R +A + + + + +K+ + + E++
Sbjct: 307 ESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEM-- 364
Query: 60 NKNKLEQANKDLEEKEKQ--LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
+ E A + K Q + +++++++ R ++ +EE+++ + + ++ E
Sbjct: 365 -HRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEM 423
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
+ + K ++N+ Q ++ + + K+ LLA K + ++ + + + +E
Sbjct: 424 KQMEVYRSHSKFMKNKIGQVKQELSR-----KDTELLALQT--KLETLTNQFSDSKQHIE 476
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXX 237
V ++ + + + + + L+ E+ + L+ E K +++++
Sbjct: 477 VLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKD 536
Query: 238 XXXXXXKTVKKLQKEVDRLEDELGIN-------KDRYKSLADEMDST 277
+ V LQK+++ L+++L K+R KSL + +T
Sbjct: 537 MLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNT 583
Score = 41.1 bits (92), Expect = 0.004
Identities = 29/151 (19%), Positives = 63/151 (41%), Gaps = 3/151 (1%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K+++ E K +T Q D+ E + E + +++ A ++ ++ + +
Sbjct: 443 VKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLR 502
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
LE+ L +K KQ+ E ++ +++ L+ E + Q+K+ Q+ +
Sbjct: 503 LEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDK 562
Query: 124 NRMCKVLENRA---QQDEERMDQLTNQLKEA 151
+ L+ R Q D D L+EA
Sbjct: 563 EKQMSSLKERVKSLQADTTNTDTALTTLEEA 593
Score = 37.1 bits (82), Expect = 0.070
Identities = 44/185 (23%), Positives = 86/185 (46%), Gaps = 23/185 (12%)
Query: 36 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI 95
AE E + L + + ++L L + K LEE E ++ E + LN + + I
Sbjct: 260 AELTEENFQRLHAEHERQAKELFLLR-------KTLEEMELRI---ETQKQTLNARDESI 309
Query: 96 EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL-KEARLL 154
++ LE Q K L A+ + +++ R ++ E A+ ++ L Q KE +L
Sbjct: 310 KKLLE-------MLQSKGLSAKATEEDHERTRRLAE--AEMHVHHLESLLEQKEKENSML 360
Query: 155 AEDADGKSDEV--SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV-GNSLKSLEVSE 211
E+ + + S K ++ +E+ + ++ S + + +LEEE++++ N S E E
Sbjct: 361 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE 420
Query: 212 EKANQ 216
E+ Q
Sbjct: 421 EEMKQ 425
Score = 36.3 bits (80), Expect = 0.12
Identities = 26/149 (17%), Positives = 70/149 (46%), Gaps = 13/149 (8%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ ++ A++L + + +Q +D E+ +L+ L E + + + K
Sbjct: 492 LQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKK 551
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+E + L +KEKQ+ ++L +V+ ++ D ++ T ++ L E +++ +
Sbjct: 552 IENLQEQLRDKEKQM-------SSLKERVKSLQADTTNTDTALTTLEEALAEKERTIE-- 602
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEAR 152
++ E R + + E+ +++ N K+ +
Sbjct: 603 ----RLKEQRDRDEREKQEEIDNYKKKKK 627
>AF086947-1|AAD03694.1| 1261|Homo sapiens dynactin 1 protein.
Length = 1261
Score = 58.4 bits (135), Expect = 3e-08
Identities = 57/232 (24%), Positives = 106/232 (45%), Gaps = 17/232 (7%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANL---RAEKVNEEVRELQKKLAQVEEDLILNK 61
K+ ++A + + D AD E D + RAE + +EV L++++ ++ DL + K
Sbjct: 267 KEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILK 326
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ-QSA 120
++E+ D QL E + A L + ++ DL SE++ QKL+E + Q
Sbjct: 327 AEIEEKGSDGAASSYQLKQLEEQNARLKDALVRM-RDLSSSEKQEHVKLQKLMEKKNQEL 385
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE-------DADGKSDEVSRKLAFVE 173
+ + + L+ Q E +D+L Q+ +A L AE D + +E R+L
Sbjct: 386 EVVRQQRERLQEELSQAESTIDELKEQV-DAALGAEEMVEMLTDRNLNLEEKVRELRETV 444
Query: 174 DELEV---AEDRVKSGDAKIS-ELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
+LE D ++ + EL E+L + G ++ + E A + V ++
Sbjct: 445 GDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADY 496
Score = 43.6 bits (98), Expect = 8e-04
Identities = 47/215 (21%), Positives = 99/215 (46%), Gaps = 11/215 (5%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN-EEVRELQKKLAQVEEDLILNKNKLE 65
+ Q LE+ + E +A+ L K+ E+V+E + K+ + + DL + +L+
Sbjct: 204 RAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADL---QRRLK 260
Query: 66 QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
+A K+ +E + E+A ++ D E +EER+ + QQ++ ++ DE
Sbjct: 261 EARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTT 320
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
++L +A+ +E+ D + + +L ++A K D + R E ++ VK
Sbjct: 321 DLEIL--KAEIEEKGSDGAASSYQLKQLEEQNARLK-DALVRMRDLSSSE---KQEHVKL 374
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ + +EL+VV + L+ +A ++E
Sbjct: 375 -QKLMEKKNQELEVVRQQRERLQEELSQAESTIDE 408
Score = 43.6 bits (98), Expect = 8e-04
Identities = 43/229 (18%), Positives = 112/229 (48%), Gaps = 14/229 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++++++ + E A++ + ++ D E + +++ +++++ K +
Sbjct: 255 LQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKER 314
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED-------LEKSEERSGTAQQKLLEA 116
+++ DLE + ++ ++ AA + +++Q+EE L + + S + +Q+ ++
Sbjct: 315 VDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKL 374
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
Q+ ++ N+ +V+ + ++ +E + Q + + E + + A G ++E+ L L
Sbjct: 375 QKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALG-AEEMVEMLTDRNLNL 433
Query: 177 E--VAEDRVKSGDAK-ISELEEELKVVGNSLKSLEVSE--EKANQRVEE 220
E V E R GD + ++E+ +EL+ + LE+ E + A RV E
Sbjct: 434 EEKVRELRETVGDLEAMNEMNDELQENARETE-LELREQLDMAGARVRE 481
Score = 43.2 bits (97), Expect = 0.001
Identities = 35/208 (16%), Positives = 89/208 (42%)
Query: 69 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
+DLEEK + L AE A +++++ + LE+ +E Q++ + Q+ E + K
Sbjct: 208 RDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAK 267
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDA 188
++ E M + ++ A L E A+ +++ + +++ +++ ++ ++ A
Sbjct: 268 EALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKA 327
Query: 189 KISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKK 248
+I E + LK LE + + + ++
Sbjct: 328 EIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEV 387
Query: 249 LQKEVDRLEDELGINKDRYKSLADEMDS 276
++++ +RL++EL + L +++D+
Sbjct: 388 VRQQRERLQEELSQAESTIDELKEQVDA 415
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/143 (23%), Positives = 67/143 (46%), Gaps = 4/143 (2%)
Query: 78 LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQD 137
L + E L +V+ +EE LE + + KL E ++ ++ +V E +++
Sbjct: 193 LPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEK---HKIQLEQVQEWKSKMQ 249
Query: 138 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 197
E++ D L +LKEAR A++A + ++A D +E+A + + + L++E+
Sbjct: 250 EQQAD-LQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEV 308
Query: 198 KVVGNSLKSLEVSEEKANQRVEE 220
+ + + L E +EE
Sbjct: 309 EALKERVDELTTDLEILKAEIEE 331
Score = 35.1 bits (77), Expect = 0.28
Identities = 32/152 (21%), Positives = 71/152 (46%), Gaps = 15/152 (9%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
K+Q + +K+ ++ ++ ++ +AE +E++E Q A E+++ L
Sbjct: 373 KLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKE-QVDAALGAEEMV---EMLTD 428
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE-----------ERSGTAQQKLLE 115
N +LEEK ++L T ++ A+N +++E+ ++E R AQ+++
Sbjct: 429 RNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEA 488
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQ 147
AQ++ + + K ++ +LTNQ
Sbjct: 489 AQETVADYQQTIKKYRQLTAHLQDVNRELTNQ 520
Score = 32.7 bits (71), Expect = 1.5
Identities = 31/139 (22%), Positives = 63/139 (45%), Gaps = 11/139 (7%)
Query: 57 LILNKNKL----EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
LI NKL ++ D E + E AAL ++ E K E+R ++
Sbjct: 879 LISTMNKLATAMQEGEYDAERPPSKPPPVELRAAALRAEITDAEGLGLKLEDRETVIKEL 938
Query: 113 L----LEAQQSADENNRMC---KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 165
++ ++ ++ N R+ K L++ A+ +ER++++ +L+E + L + + +E
Sbjct: 939 KKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLRKKEKEFEET 998
Query: 166 SRKLAFVEDELEVAEDRVK 184
L D+LE + +K
Sbjct: 999 MDALQADIDQLEAEKAELK 1017
Score = 32.7 bits (71), Expect = 1.5
Identities = 26/105 (24%), Positives = 49/105 (46%), Gaps = 8/105 (7%)
Query: 29 ARDANLRAEKVNEEVRELQK-------KLAQVEEDLILNKNKLEQANKDLEEK-EKQLTA 80
A L+ E ++EL+K +L++ L L + KL+ A KD +E+ EK T
Sbjct: 921 AEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTR 980
Query: 81 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
E A L +K ++ EE ++ + + + E +Q + ++
Sbjct: 981 LEETQALLRKKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSK 1025
>AF064205-2|AAD55812.1| 1144|Homo sapiens dynactin 1 p135 isoform
protein.
Length = 1144
Score = 58.4 bits (135), Expect = 3e-08
Identities = 57/232 (24%), Positives = 106/232 (45%), Gaps = 17/232 (7%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANL---RAEKVNEEVRELQKKLAQVEEDLILNK 61
K+ ++A + + D AD E D + RAE + +EV L++++ ++ DL + K
Sbjct: 150 KEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILK 209
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ-QSA 120
++E+ D QL E + A L + ++ DL SE++ QKL+E + Q
Sbjct: 210 AEIEEKGSDGAASSYQLKQLEEQNARLKDALVRM-RDLSSSEKQEHVKLQKLMEKKNQEL 268
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE-------DADGKSDEVSRKLAFVE 173
+ + + L+ Q E +D+L Q+ +A L AE D + +E R+L
Sbjct: 269 EVVRQQRERLQEELSQAESTIDELKEQV-DAALGAEEMVEMLTDRNLNLEEKVRELRETV 327
Query: 174 DELEV---AEDRVKSGDAKIS-ELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
+LE D ++ + EL E+L + G ++ + E A + V ++
Sbjct: 328 GDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADY 379
Score = 43.6 bits (98), Expect = 8e-04
Identities = 47/215 (21%), Positives = 99/215 (46%), Gaps = 11/215 (5%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN-EEVRELQKKLAQVEEDLILNKNKLE 65
+ Q LE+ + E +A+ L K+ E+V+E + K+ + + DL + +L+
Sbjct: 87 RAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADL---QRRLK 143
Query: 66 QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
+A K+ +E + E+A ++ D E +EER+ + QQ++ ++ DE
Sbjct: 144 EARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTT 203
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
++L +A+ +E+ D + + +L ++A K D + R E ++ VK
Sbjct: 204 DLEIL--KAEIEEKGSDGAASSYQLKQLEEQNARLK-DALVRMRDLSSSE---KQEHVKL 257
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ + +EL+VV + L+ +A ++E
Sbjct: 258 -QKLMEKKNQELEVVRQQRERLQEELSQAESTIDE 291
Score = 43.6 bits (98), Expect = 8e-04
Identities = 43/229 (18%), Positives = 112/229 (48%), Gaps = 14/229 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++++++ + E A++ + ++ D E + +++ +++++ K +
Sbjct: 138 LQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKER 197
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED-------LEKSEERSGTAQQKLLEA 116
+++ DLE + ++ ++ AA + +++Q+EE L + + S + +Q+ ++
Sbjct: 198 VDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKL 257
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
Q+ ++ N+ +V+ + ++ +E + Q + + E + + A G ++E+ L L
Sbjct: 258 QKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALG-AEEMVEMLTDRNLNL 316
Query: 177 E--VAEDRVKSGDAK-ISELEEELKVVGNSLKSLEVSE--EKANQRVEE 220
E V E R GD + ++E+ +EL+ + LE+ E + A RV E
Sbjct: 317 EEKVRELRETVGDLEAMNEMNDELQENARETE-LELREQLDMAGARVRE 364
Score = 43.2 bits (97), Expect = 0.001
Identities = 35/208 (16%), Positives = 89/208 (42%)
Query: 69 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
+DLEEK + L AE A +++++ + LE+ +E Q++ + Q+ E + K
Sbjct: 91 RDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAK 150
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDA 188
++ E M + ++ A L E A+ +++ + +++ +++ ++ ++ A
Sbjct: 151 EALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKA 210
Query: 189 KISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKK 248
+I E + LK LE + + + ++
Sbjct: 211 EIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEV 270
Query: 249 LQKEVDRLEDELGINKDRYKSLADEMDS 276
++++ +RL++EL + L +++D+
Sbjct: 271 VRQQRERLQEELSQAESTIDELKEQVDA 298
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/143 (23%), Positives = 67/143 (46%), Gaps = 4/143 (2%)
Query: 78 LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQD 137
L + E L +V+ +EE LE + + KL E ++ ++ +V E +++
Sbjct: 76 LPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEK---HKIQLEQVQEWKSKMQ 132
Query: 138 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 197
E++ D L +LKEAR A++A + ++A D +E+A + + + L++E+
Sbjct: 133 EQQAD-LQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEV 191
Query: 198 KVVGNSLKSLEVSEEKANQRVEE 220
+ + + L E +EE
Sbjct: 192 EALKERVDELTTDLEILKAEIEE 214
Score = 35.1 bits (77), Expect = 0.28
Identities = 32/152 (21%), Positives = 71/152 (46%), Gaps = 15/152 (9%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
K+Q + +K+ ++ ++ ++ +AE +E++E Q A E+++ L
Sbjct: 256 KLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKE-QVDAALGAEEMV---EMLTD 311
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE-----------ERSGTAQQKLLE 115
N +LEEK ++L T ++ A+N +++E+ ++E R AQ+++
Sbjct: 312 RNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEA 371
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQ 147
AQ++ + + K ++ +LTNQ
Sbjct: 372 AQETVADYQQTIKKYRQLTAHLQDVNRELTNQ 403
Score = 32.7 bits (71), Expect = 1.5
Identities = 31/139 (22%), Positives = 63/139 (45%), Gaps = 11/139 (7%)
Query: 57 LILNKNKL----EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
LI NKL ++ D E + E AAL ++ E K E+R ++
Sbjct: 762 LISTMNKLATAMQEGEYDAERPPSKPPPVELRAAALRAEITDAEGLGLKLEDRETVIKEL 821
Query: 113 L----LEAQQSADENNRMC---KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 165
++ ++ ++ N R+ K L++ A+ +ER++++ +L+E + L + + +E
Sbjct: 822 KKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLRKKEKEFEET 881
Query: 166 SRKLAFVEDELEVAEDRVK 184
L D+LE + +K
Sbjct: 882 MDALQADIDQLEAEKAELK 900
Score = 32.7 bits (71), Expect = 1.5
Identities = 26/105 (24%), Positives = 49/105 (46%), Gaps = 8/105 (7%)
Query: 29 ARDANLRAEKVNEEVRELQK-------KLAQVEEDLILNKNKLEQANKDLEEK-EKQLTA 80
A L+ E ++EL+K +L++ L L + KL+ A KD +E+ EK T
Sbjct: 804 AEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTR 863
Query: 81 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
E A L +K ++ EE ++ + + + E +Q + ++
Sbjct: 864 LEETQALLRKKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSK 908
>AF064205-1|AAD55811.1| 1278|Homo sapiens dynactin 1 p150 isoform
protein.
Length = 1278
Score = 58.4 bits (135), Expect = 3e-08
Identities = 57/232 (24%), Positives = 106/232 (45%), Gaps = 17/232 (7%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANL---RAEKVNEEVRELQKKLAQVEEDLILNK 61
K+ ++A + + D AD E D + RAE + +EV L++++ ++ DL + K
Sbjct: 284 KEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILK 343
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ-QSA 120
++E+ D QL E + A L + ++ DL SE++ QKL+E + Q
Sbjct: 344 AEIEEKGSDGAASSYQLKQLEEQNARLKDALVRM-RDLSSSEKQEHVKLQKLMEKKNQEL 402
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE-------DADGKSDEVSRKLAFVE 173
+ + + L+ Q E +D+L Q+ +A L AE D + +E R+L
Sbjct: 403 EVVRQQRERLQEELSQAESTIDELKEQV-DAALGAEEMVEMLTDRNLNLEEKVRELRETV 461
Query: 174 DELEV---AEDRVKSGDAKIS-ELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
+LE D ++ + EL E+L + G ++ + E A + V ++
Sbjct: 462 GDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADY 513
Score = 43.6 bits (98), Expect = 8e-04
Identities = 47/215 (21%), Positives = 99/215 (46%), Gaps = 11/215 (5%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN-EEVRELQKKLAQVEEDLILNKNKLE 65
+ Q LE+ + E +A+ L K+ E+V+E + K+ + + DL + +L+
Sbjct: 221 RAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADL---QRRLK 277
Query: 66 QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
+A K+ +E + E+A ++ D E +EER+ + QQ++ ++ DE
Sbjct: 278 EARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTT 337
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
++L +A+ +E+ D + + +L ++A K D + R E ++ VK
Sbjct: 338 DLEIL--KAEIEEKGSDGAASSYQLKQLEEQNARLK-DALVRMRDLSSSE---KQEHVKL 391
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ + +EL+VV + L+ +A ++E
Sbjct: 392 -QKLMEKKNQELEVVRQQRERLQEELSQAESTIDE 425
Score = 43.6 bits (98), Expect = 8e-04
Identities = 43/229 (18%), Positives = 112/229 (48%), Gaps = 14/229 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++++++ + E A++ + ++ D E + +++ +++++ K +
Sbjct: 272 LQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKER 331
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED-------LEKSEERSGTAQQKLLEA 116
+++ DLE + ++ ++ AA + +++Q+EE L + + S + +Q+ ++
Sbjct: 332 VDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKL 391
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
Q+ ++ N+ +V+ + ++ +E + Q + + E + + A G ++E+ L L
Sbjct: 392 QKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALG-AEEMVEMLTDRNLNL 450
Query: 177 E--VAEDRVKSGDAK-ISELEEELKVVGNSLKSLEVSE--EKANQRVEE 220
E V E R GD + ++E+ +EL+ + LE+ E + A RV E
Sbjct: 451 EEKVRELRETVGDLEAMNEMNDELQENARETE-LELREQLDMAGARVRE 498
Score = 43.2 bits (97), Expect = 0.001
Identities = 35/208 (16%), Positives = 89/208 (42%)
Query: 69 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
+DLEEK + L AE A +++++ + LE+ +E Q++ + Q+ E + K
Sbjct: 225 RDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAK 284
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDA 188
++ E M + ++ A L E A+ +++ + +++ +++ ++ ++ A
Sbjct: 285 EALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKA 344
Query: 189 KISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKK 248
+I E + LK LE + + + ++
Sbjct: 345 EIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEV 404
Query: 249 LQKEVDRLEDELGINKDRYKSLADEMDS 276
++++ +RL++EL + L +++D+
Sbjct: 405 VRQQRERLQEELSQAESTIDELKEQVDA 432
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/143 (23%), Positives = 67/143 (46%), Gaps = 4/143 (2%)
Query: 78 LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQD 137
L + E L +V+ +EE LE + + KL E ++ ++ +V E +++
Sbjct: 210 LPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEK---HKIQLEQVQEWKSKMQ 266
Query: 138 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 197
E++ D L +LKEAR A++A + ++A D +E+A + + + L++E+
Sbjct: 267 EQQAD-LQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEV 325
Query: 198 KVVGNSLKSLEVSEEKANQRVEE 220
+ + + L E +EE
Sbjct: 326 EALKERVDELTTDLEILKAEIEE 348
Score = 35.1 bits (77), Expect = 0.28
Identities = 32/152 (21%), Positives = 71/152 (46%), Gaps = 15/152 (9%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
K+Q + +K+ ++ ++ ++ +AE +E++E Q A E+++ L
Sbjct: 390 KLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKE-QVDAALGAEEMV---EMLTD 445
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE-----------ERSGTAQQKLLE 115
N +LEEK ++L T ++ A+N +++E+ ++E R AQ+++
Sbjct: 446 RNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEA 505
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQ 147
AQ++ + + K ++ +LTNQ
Sbjct: 506 AQETVADYQQTIKKYRQLTAHLQDVNRELTNQ 537
Score = 32.7 bits (71), Expect = 1.5
Identities = 31/139 (22%), Positives = 63/139 (45%), Gaps = 11/139 (7%)
Query: 57 LILNKNKL----EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
LI NKL ++ D E + E AAL ++ E K E+R ++
Sbjct: 896 LISTMNKLATAMQEGEYDAERPPSKPPPVELRAAALRAEITDAEGLGLKLEDRETVIKEL 955
Query: 113 L----LEAQQSADENNRMC---KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 165
++ ++ ++ N R+ K L++ A+ +ER++++ +L+E + L + + +E
Sbjct: 956 KKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLRKKEKEFEET 1015
Query: 166 SRKLAFVEDELEVAEDRVK 184
L D+LE + +K
Sbjct: 1016 MDALQADIDQLEAEKAELK 1034
Score = 32.7 bits (71), Expect = 1.5
Identities = 26/105 (24%), Positives = 49/105 (46%), Gaps = 8/105 (7%)
Query: 29 ARDANLRAEKVNEEVRELQK-------KLAQVEEDLILNKNKLEQANKDLEEK-EKQLTA 80
A L+ E ++EL+K +L++ L L + KL+ A KD +E+ EK T
Sbjct: 938 AEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTR 997
Query: 81 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
E A L +K ++ EE ++ + + + E +Q + ++
Sbjct: 998 LEETQALLRKKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSK 1042
>AB209625-1|BAD92862.1| 459|Homo sapiens dynactin 1 isoform 1
variant protein.
Length = 459
Score = 58.4 bits (135), Expect = 3e-08
Identities = 57/232 (24%), Positives = 106/232 (45%), Gaps = 17/232 (7%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANL---RAEKVNEEVRELQKKLAQVEEDLILNK 61
K+ ++A + + D AD E D + RAE + +EV L++++ ++ DL + K
Sbjct: 109 KEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILK 168
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ-QSA 120
++E+ D QL E + A L + ++ DL SE++ QKL+E + Q
Sbjct: 169 AEIEEKGSDGAASSYQLKQLEEQNARLKDALVRM-RDLSSSEKQEHVKLQKLMEKKNQEL 227
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE-------DADGKSDEVSRKLAFVE 173
+ + + L+ Q E +D+L Q+ +A L AE D + +E R+L
Sbjct: 228 EVVRQQRERLQEELSQAESTIDELKEQV-DAALGAEEMVEMLTDRNLNLEEKVRELRETV 286
Query: 174 DELEV---AEDRVKSGDAKIS-ELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
+LE D ++ + EL E+L + G ++ + E A + V ++
Sbjct: 287 GDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADY 338
Score = 43.6 bits (98), Expect = 8e-04
Identities = 47/215 (21%), Positives = 99/215 (46%), Gaps = 11/215 (5%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN-EEVRELQKKLAQVEEDLILNKNKLE 65
+ Q LE+ + E +A+ L K+ E+V+E + K+ + + DL + +L+
Sbjct: 46 RAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADL---QRRLK 102
Query: 66 QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
+A K+ +E + E+A ++ D E +EER+ + QQ++ ++ DE
Sbjct: 103 EARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTT 162
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
++L +A+ +E+ D + + +L ++A K D + R E ++ VK
Sbjct: 163 DLEIL--KAEIEEKGSDGAASSYQLKQLEEQNARLK-DALVRMRDLSSSE---KQEHVKL 216
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ + +EL+VV + L+ +A ++E
Sbjct: 217 -QKLMEKKNQELEVVRQQRERLQEELSQAESTIDE 250
Score = 43.6 bits (98), Expect = 8e-04
Identities = 43/229 (18%), Positives = 112/229 (48%), Gaps = 14/229 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++++++ + E A++ + ++ D E + +++ +++++ K +
Sbjct: 97 LQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKER 156
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED-------LEKSEERSGTAQQKLLEA 116
+++ DLE + ++ ++ AA + +++Q+EE L + + S + +Q+ ++
Sbjct: 157 VDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKL 216
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
Q+ ++ N+ +V+ + ++ +E + Q + + E + + A G ++E+ L L
Sbjct: 217 QKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALG-AEEMVEMLTDRNLNL 275
Query: 177 E--VAEDRVKSGDAK-ISELEEELKVVGNSLKSLEVSE--EKANQRVEE 220
E V E R GD + ++E+ +EL+ + LE+ E + A RV E
Sbjct: 276 EEKVRELRETVGDLEAMNEMNDELQENARETE-LELREQLDMAGARVRE 323
Score = 43.2 bits (97), Expect = 0.001
Identities = 35/208 (16%), Positives = 89/208 (42%)
Query: 69 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
+DLEEK + L AE A +++++ + LE+ +E Q++ + Q+ E + K
Sbjct: 50 RDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAK 109
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDA 188
++ E M + ++ A L E A+ +++ + +++ +++ ++ ++ A
Sbjct: 110 EALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKA 169
Query: 189 KISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKK 248
+I E + LK LE + + + ++
Sbjct: 170 EIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEV 229
Query: 249 LQKEVDRLEDELGINKDRYKSLADEMDS 276
++++ +RL++EL + L +++D+
Sbjct: 230 VRQQRERLQEELSQAESTIDELKEQVDA 257
Score = 41.5 bits (93), Expect = 0.003
Identities = 32/137 (23%), Positives = 65/137 (47%), Gaps = 4/137 (2%)
Query: 84 EVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQ 143
E L +V+ +EE LE + + KL E ++ ++ +V E +++ E++ D
Sbjct: 41 EEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEK---HKIQLEQVQEWKSKMQEQQAD- 96
Query: 144 LTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNS 203
L +LKEAR A++A + ++A D +E+A + + + L++E++ +
Sbjct: 97 LQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKER 156
Query: 204 LKSLEVSEEKANQRVEE 220
+ L E +EE
Sbjct: 157 VDELTTDLEILKAEIEE 173
Score = 35.1 bits (77), Expect = 0.28
Identities = 32/152 (21%), Positives = 71/152 (46%), Gaps = 15/152 (9%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
K+Q + +K+ ++ ++ ++ +AE +E++E Q A E+++ L
Sbjct: 215 KLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKE-QVDAALGAEEMV---EMLTD 270
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE-----------ERSGTAQQKLLE 115
N +LEEK ++L T ++ A+N +++E+ ++E R AQ+++
Sbjct: 271 RNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEA 330
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQ 147
AQ++ + + K ++ +LTNQ
Sbjct: 331 AQETVADYQQTIKKYRQLTAHLQDVNRELTNQ 362
>Z97054-3|CAI42646.1| 1233|Homo sapiens structural maintenance of
chromosomes 1A protein.
Length = 1233
Score = 57.6 bits (133), Expect = 5e-08
Identities = 42/159 (26%), Positives = 86/159 (54%), Gaps = 8/159 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQ-QARDANLRAEKVNEEVR---ELQKKLAQVEED 56
MD ++K+M +++ + ++ + Q Q RD L +V + R E K+ A + ++
Sbjct: 333 MDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQE 392
Query: 57 LI-LNKN-KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
L N++ K +Q DLEE++K TEA++ R++++ ++ +EK EE T++Q L
Sbjct: 393 LEKFNRDQKADQDRLDLEERKK--VETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLE 450
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 153
E ++ E ++ + R + + ++Q+ QL +AR+
Sbjct: 451 EQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARI 489
Score = 53.6 bits (123), Expect = 8e-07
Identities = 44/201 (21%), Positives = 93/201 (46%), Gaps = 7/201 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE-EDLIL 59
++A KK +Q + D E++ L EK +E E ++ +Q + DL L
Sbjct: 312 LEAAKKSLQNAQKHYKKRKGDMDELEKEM----LSVEKARQEFEERMEEESQSQGRDLTL 367
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
+N++++ ++ EE K+ E+ NR + ++ L+ E + + K+ + +
Sbjct: 368 EENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLRE 427
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+EN + + LE ++ +++ E E A + DE++++L V ++L A
Sbjct: 428 IEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDA 487
Query: 180 E-DRVKSG-DAKISELEEELK 198
DR +S + +E+ E +K
Sbjct: 488 RIDRQESSRQQRKAEIMESIK 508
Score = 50.0 bits (114), Expect = 9e-06
Identities = 65/291 (22%), Positives = 129/291 (44%), Gaps = 37/291 (12%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAE------KV--NE-EVRELQKKLAQVEE 55
KK + A + E ++AD Q+ +D +RA+ K+ NE E+ +L K+LA +
Sbjct: 189 KKNIAAERKEAKQEKEEADRY-QRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNK 247
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-------KSEERSGT 108
++ +K ++++ +L+EK+K+L E + +++++ + +L K++E +
Sbjct: 248 EIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSH 307
Query: 109 AQQKLLEAQQS--------------ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 154
+KL A++S DE + +E Q+ EERM++ + L
Sbjct: 308 KIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTL 367
Query: 155 AEDADGK----SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVS 210
E+ K +E S++ A + ELE +R + D +LEE KV + ++
Sbjct: 368 EENQVKKYHRLKEEASKRAATLAQELE-KFNRDQKADQDRLDLEERKKVETEAKIKQKLR 426
Query: 211 EEKANQ-RVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
E + NQ R+E+ + V+ ++ +D + EL
Sbjct: 427 EIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKEL 477
Score = 40.7 bits (91), Expect = 0.006
Identities = 50/222 (22%), Positives = 96/222 (43%), Gaps = 27/222 (12%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-------VRELQKKLAQVEED 56
I+ + +L++D DK EQ + EK+ +E + E +L ++
Sbjct: 819 IQLDFEKNQLKEDQ--DKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQ 876
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+ K+++ N ++EE K+L E+ L ++V IE LE ++RS + LL+A
Sbjct: 877 HLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLE--QKRSD--RHNLLQA 932
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
CK+ + + + MD ++ + E ED+ S +S + + L
Sbjct: 933 ----------CKMQDIKLPLSKGTMDDISQE--EGSSQGEDSVSGSQRISS--IYAREAL 978
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
+ D K ++ EEE+K N+L+ ++ QR+
Sbjct: 979 IEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRI 1020
Score = 33.5 bits (73), Expect = 0.86
Identities = 28/162 (17%), Positives = 75/162 (46%), Gaps = 10/162 (6%)
Query: 26 EQQARDANLRAEKVNEEV-----RELQ-KKLAQVEEDLILNKNKLEQANKDLEEKEK--- 76
E++ +D + +V +EV RE+ + + + EE+ + +N++ + + E ++
Sbjct: 759 EREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLG 818
Query: 77 -QLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 135
QL + ++ KV E+ ++K E +++ + DE + L+N+
Sbjct: 819 IQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHL 878
Query: 136 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
+ ++ ++++E R A+ + + +++ +E +LE
Sbjct: 879 AKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLE 920
Score = 32.7 bits (71), Expect = 1.5
Identities = 45/217 (20%), Positives = 89/217 (41%), Gaps = 21/217 (9%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-------AQV 53
++ +KK+ Q D M + + Q N E+ E++KKL +
Sbjct: 849 IEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHL 908
Query: 54 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI--EEDLEKSEER-SGTAQ 110
++++ + KLEQ D + + ++ + I EE + E+ SG+ +
Sbjct: 909 QKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGSSQGEDSVSGSQR 968
Query: 111 QKLLEAQQSADE--NNRMCKVLENRAQQDE--ERMDQLTNQLKE-----ARLLAED--AD 159
+ A+++ E +C+ L++ ++E + M+ L +L E R+ A + A
Sbjct: 969 ISSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAM 1028
Query: 160 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 196
K + V K DE E A R K ++++E
Sbjct: 1029 EKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKE 1065
Score = 31.5 bits (68), Expect = 3.5
Identities = 26/132 (19%), Positives = 55/132 (41%), Gaps = 3/132 (2%)
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
E+ KDL+EK Q+ E V+ I E E+ +R +K LE +
Sbjct: 759 EREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLG 818
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
+N+ ++D++++ +K+ + + E R + +++ + +D
Sbjct: 819 IQLDFEKNQLKEDQDKVHMWEQTVKKDE---NEIEKLKKEEQRHMKIIDETMAQLQDLKN 875
Query: 185 SGDAKISELEEE 196
AK SE+ ++
Sbjct: 876 QHLAKKSEVNDK 887
>S78271-1|AAB34405.1| 1233|Homo sapiens SB1.8/DXS423E protein.
Length = 1233
Score = 57.6 bits (133), Expect = 5e-08
Identities = 42/159 (26%), Positives = 86/159 (54%), Gaps = 8/159 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQ-QARDANLRAEKVNEEVR---ELQKKLAQVEED 56
MD ++K+M +++ + ++ + Q Q RD L +V + R E K+ A + ++
Sbjct: 333 MDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQE 392
Query: 57 LI-LNKN-KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
L N++ K +Q DLEE++K TEA++ R++++ ++ +EK EE T++Q L
Sbjct: 393 LEKFNRDQKADQDRLDLEERKK--VETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLE 450
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 153
E ++ E ++ + R + + ++Q+ QL +AR+
Sbjct: 451 EQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARI 489
Score = 53.6 bits (123), Expect = 8e-07
Identities = 44/201 (21%), Positives = 93/201 (46%), Gaps = 7/201 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE-EDLIL 59
++A KK +Q + D E++ L EK +E E ++ +Q + DL L
Sbjct: 312 LEAAKKSLQNAQKHYKKRKGDMDELEKEM----LSVEKARQEFEERMEEESQSQGRDLTL 367
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
+N++++ ++ EE K+ E+ NR + ++ L+ E + + K+ + +
Sbjct: 368 EENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLRE 427
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+EN + + LE ++ +++ E E A + DE++++L V ++L A
Sbjct: 428 IEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDA 487
Query: 180 E-DRVKSG-DAKISELEEELK 198
DR +S + +E+ E +K
Sbjct: 488 RIDRQESSRQQRKAEIMESIK 508
Score = 50.0 bits (114), Expect = 9e-06
Identities = 65/291 (22%), Positives = 129/291 (44%), Gaps = 37/291 (12%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAE------KV--NE-EVRELQKKLAQVEE 55
KK + A + E ++AD Q+ +D +RA+ K+ NE E+ +L K+LA +
Sbjct: 189 KKNIAAERKEAKQEKEEADRY-QRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNK 247
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-------KSEERSGT 108
++ +K ++++ +L+EK+K+L E + +++++ + +L K++E +
Sbjct: 248 EIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSH 307
Query: 109 AQQKLLEAQQS--------------ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 154
+KL A++S DE + +E Q+ EERM++ + L
Sbjct: 308 KIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTL 367
Query: 155 AEDADGK----SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVS 210
E+ K +E S++ A + ELE +R + D +LEE KV + ++
Sbjct: 368 EENQVKKYHRLKEEASKRAATLAQELE-KFNRDQKADQDRLDLEERKKVETEAKIKQKLR 426
Query: 211 EEKANQ-RVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
E + NQ R+E+ + V+ ++ +D + EL
Sbjct: 427 EIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKEL 477
Score = 40.7 bits (91), Expect = 0.006
Identities = 50/222 (22%), Positives = 96/222 (43%), Gaps = 27/222 (12%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-------VRELQKKLAQVEED 56
I+ + +L++D DK EQ + EK+ +E + E +L ++
Sbjct: 819 IQLDFEKNQLKEDQ--DKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQ 876
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+ K+++ N ++EE K+L E+ L ++V IE LE ++RS + LL+A
Sbjct: 877 HLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLE--QKRSD--RHNLLQA 932
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
CK+ + + + MD ++ + E ED+ S +S + + L
Sbjct: 933 ----------CKMQDIKLPLSKGTMDDISQE--EGSSQGEDSVSGSQRISS--IYAREAL 978
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
+ D K ++ EEE+K N+L+ ++ QR+
Sbjct: 979 IEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRI 1020
Score = 33.5 bits (73), Expect = 0.86
Identities = 28/162 (17%), Positives = 75/162 (46%), Gaps = 10/162 (6%)
Query: 26 EQQARDANLRAEKVNEEV-----RELQ-KKLAQVEEDLILNKNKLEQANKDLEEKEK--- 76
E++ +D + +V +EV RE+ + + + EE+ + +N++ + + E ++
Sbjct: 759 EREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLG 818
Query: 77 -QLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 135
QL + ++ KV E+ ++K E +++ + DE + L+N+
Sbjct: 819 IQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHL 878
Query: 136 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
+ ++ ++++E R A+ + + +++ +E +LE
Sbjct: 879 AKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLE 920
Score = 32.7 bits (71), Expect = 1.5
Identities = 45/217 (20%), Positives = 89/217 (41%), Gaps = 21/217 (9%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-------AQV 53
++ +KK+ Q D M + + Q N E+ E++KKL +
Sbjct: 849 IEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHL 908
Query: 54 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI--EEDLEKSEER-SGTAQ 110
++++ + KLEQ D + + ++ + I EE + E+ SG+ +
Sbjct: 909 QKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGSSQGEDSVSGSQR 968
Query: 111 QKLLEAQQSADE--NNRMCKVLENRAQQDE--ERMDQLTNQLKE-----ARLLAED--AD 159
+ A+++ E +C+ L++ ++E + M+ L +L E R+ A + A
Sbjct: 969 ISSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAM 1028
Query: 160 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 196
K + V K DE E A R K ++++E
Sbjct: 1029 EKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKE 1065
Score = 31.5 bits (68), Expect = 3.5
Identities = 26/132 (19%), Positives = 55/132 (41%), Gaps = 3/132 (2%)
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
E+ KDL+EK Q+ E V+ I E E+ +R +K LE +
Sbjct: 759 EREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLG 818
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
+N+ ++D++++ +K+ + + E R + +++ + +D
Sbjct: 819 IQLDFEKNQLKEDQDKVHMWEQTVKKDE---NEIEKLKKEEQRHMKIIDETMAQLQDLKN 875
Query: 185 SGDAKISELEEE 196
AK SE+ ++
Sbjct: 876 QHLAKKSEVNDK 887
>M12128-1|AAA36775.1| 96|Homo sapiens protein ( Human cytoskeletal
tropomyosin isoform (2.5 kb) mRNA, 3' end. ).
Length = 96
Score = 57.6 bits (133), Expect = 5e-08
Identities = 26/96 (27%), Positives = 53/96 (55%)
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
K +EV+RKL +E +LE E+R + +++ E++E+++++ +LK L +EEK +Q+ ++
Sbjct: 1 KYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDK 60
Query: 221 FXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRL 256
+ ++V KL+K +D L
Sbjct: 61 YEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDL 96
Score = 40.7 bits (91), Expect = 0.006
Identities = 26/77 (33%), Positives = 43/77 (55%), Gaps = 7/77 (9%)
Query: 90 RKVQQIEEDLEKSEERSGTAQQKLLEAQQS---ADENNRMCKVLENRAQQDEERMDQ--- 143
RK+ IE DLE++EER+ A+ + E + D+N + E + Q E++ ++
Sbjct: 7 RKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIK 66
Query: 144 -LTNQLKEARLLAEDAD 159
LT++LKEA AE A+
Sbjct: 67 ILTDKLKEAETRAEFAE 83
Score = 35.1 bits (77), Expect = 0.28
Identities = 17/87 (19%), Positives = 43/87 (49%)
Query: 111 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 170
+KL+ + + ++ E+R ++ +E++ + LK E K D+ ++
Sbjct: 7 RKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIK 66
Query: 171 FVEDELEVAEDRVKSGDAKISELEEEL 197
+ D+L+ AE R + + +++LE+ +
Sbjct: 67 ILTDKLKEAETRAEFAERSVAKLEKTI 93
>D80000-1|BAA11495.2| 1233|Homo sapiens KIAA0178 protein.
Length = 1233
Score = 57.6 bits (133), Expect = 5e-08
Identities = 42/159 (26%), Positives = 86/159 (54%), Gaps = 8/159 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQ-QARDANLRAEKVNEEVR---ELQKKLAQVEED 56
MD ++K+M +++ + ++ + Q Q RD L +V + R E K+ A + ++
Sbjct: 333 MDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQE 392
Query: 57 LI-LNKN-KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
L N++ K +Q DLEE++K TEA++ R++++ ++ +EK EE T++Q L
Sbjct: 393 LEKFNRDQKADQDRLDLEERKK--VETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLE 450
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 153
E ++ E ++ + R + + ++Q+ QL +AR+
Sbjct: 451 EQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARI 489
Score = 53.6 bits (123), Expect = 8e-07
Identities = 44/201 (21%), Positives = 93/201 (46%), Gaps = 7/201 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE-EDLIL 59
++A KK +Q + D E++ L EK +E E ++ +Q + DL L
Sbjct: 312 LEAAKKSLQNAQKHYKKRKGDMDELEKEM----LSVEKARQEFEERMEEESQSQGRDLTL 367
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
+N++++ ++ EE K+ E+ NR + ++ L+ E + + K+ + +
Sbjct: 368 EENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLRE 427
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+EN + + LE ++ +++ E E A + DE++++L V ++L A
Sbjct: 428 IEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDA 487
Query: 180 E-DRVKSG-DAKISELEEELK 198
DR +S + +E+ E +K
Sbjct: 488 RIDRQESSRQQRKAEIMESIK 508
Score = 50.0 bits (114), Expect = 9e-06
Identities = 65/291 (22%), Positives = 129/291 (44%), Gaps = 37/291 (12%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAE------KV--NE-EVRELQKKLAQVEE 55
KK + A + E ++AD Q+ +D +RA+ K+ NE E+ +L K+LA +
Sbjct: 189 KKNIAAERKEAKQEKEEADRY-QRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNK 247
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-------KSEERSGT 108
++ +K ++++ +L+EK+K+L E + +++++ + +L K++E +
Sbjct: 248 EIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSH 307
Query: 109 AQQKLLEAQQS--------------ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 154
+KL A++S DE + +E Q+ EERM++ + L
Sbjct: 308 KIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTL 367
Query: 155 AEDADGK----SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVS 210
E+ K +E S++ A + ELE +R + D +LEE KV + ++
Sbjct: 368 EENQVKKYHRLKEEASKRAATLAQELE-KFNRDQKADQDRLDLEERKKVETEAKIKQKLR 426
Query: 211 EEKANQ-RVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
E + NQ R+E+ + V+ ++ +D + EL
Sbjct: 427 EIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKEL 477
Score = 40.7 bits (91), Expect = 0.006
Identities = 50/222 (22%), Positives = 96/222 (43%), Gaps = 27/222 (12%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-------VRELQKKLAQVEED 56
I+ + +L++D DK EQ + EK+ +E + E +L ++
Sbjct: 819 IQLDFEKNQLKEDQ--DKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQ 876
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+ K+++ N ++EE K+L E+ L ++V IE LE ++RS + LL+A
Sbjct: 877 HLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLE--QKRSD--RHNLLQA 932
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
CK+ + + + MD ++ + E ED+ S +S + + L
Sbjct: 933 ----------CKMQDIKLPLSKGTMDDISQE--EGSSQGEDSVSGSQRISS--IYAREAL 978
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
+ D K ++ EEE+K N+L+ ++ QR+
Sbjct: 979 IEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRI 1020
Score = 33.5 bits (73), Expect = 0.86
Identities = 28/162 (17%), Positives = 75/162 (46%), Gaps = 10/162 (6%)
Query: 26 EQQARDANLRAEKVNEEV-----RELQ-KKLAQVEEDLILNKNKLEQANKDLEEKEK--- 76
E++ +D + +V +EV RE+ + + + EE+ + +N++ + + E ++
Sbjct: 759 EREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLG 818
Query: 77 -QLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 135
QL + ++ KV E+ ++K E +++ + DE + L+N+
Sbjct: 819 IQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHL 878
Query: 136 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
+ ++ ++++E R A+ + + +++ +E +LE
Sbjct: 879 AKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLE 920
Score = 32.7 bits (71), Expect = 1.5
Identities = 45/217 (20%), Positives = 89/217 (41%), Gaps = 21/217 (9%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-------AQV 53
++ +KK+ Q D M + + Q N E+ E++KKL +
Sbjct: 849 IEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHL 908
Query: 54 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI--EEDLEKSEER-SGTAQ 110
++++ + KLEQ D + + ++ + I EE + E+ SG+ +
Sbjct: 909 QKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGSSQGEDSVSGSQR 968
Query: 111 QKLLEAQQSADE--NNRMCKVLENRAQQDE--ERMDQLTNQLKE-----ARLLAED--AD 159
+ A+++ E +C+ L++ ++E + M+ L +L E R+ A + A
Sbjct: 969 ISSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAM 1028
Query: 160 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 196
K + V K DE E A R K ++++E
Sbjct: 1029 EKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKE 1065
Score = 31.5 bits (68), Expect = 3.5
Identities = 26/132 (19%), Positives = 55/132 (41%), Gaps = 3/132 (2%)
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
E+ KDL+EK Q+ E V+ I E E+ +R +K LE +
Sbjct: 759 EREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLG 818
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
+N+ ++D++++ +K+ + + E R + +++ + +D
Sbjct: 819 IQLDFEKNQLKEDQDKVHMWEQTVKKDE---NEIEKLKKEEQRHMKIIDETMAQLQDLKN 875
Query: 185 SGDAKISELEEE 196
AK SE+ ++
Sbjct: 876 QHLAKKSEVNDK 887
>BC112127-1|AAI12128.1| 1233|Homo sapiens SMC1 structural
maintenance of chromosomes 1-like 1 protein.
Length = 1233
Score = 57.6 bits (133), Expect = 5e-08
Identities = 42/159 (26%), Positives = 86/159 (54%), Gaps = 8/159 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQ-QARDANLRAEKVNEEVR---ELQKKLAQVEED 56
MD ++K+M +++ + ++ + Q Q RD L +V + R E K+ A + ++
Sbjct: 333 MDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQE 392
Query: 57 LI-LNKN-KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
L N++ K +Q DLEE++K TEA++ R++++ ++ +EK EE T++Q L
Sbjct: 393 LEKFNRDQKADQDRLDLEERKK--VETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLE 450
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 153
E ++ E ++ + R + + ++Q+ QL +AR+
Sbjct: 451 EQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARI 489
Score = 53.6 bits (123), Expect = 8e-07
Identities = 44/201 (21%), Positives = 93/201 (46%), Gaps = 7/201 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE-EDLIL 59
++A KK +Q + D E++ L EK +E E ++ +Q + DL L
Sbjct: 312 LEAAKKSLQNAQKHYKKRKGDMDELEKEM----LSVEKARQEFEERMEEESQSQGRDLTL 367
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
+N++++ ++ EE K+ E+ NR + ++ L+ E + + K+ + +
Sbjct: 368 EENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLRE 427
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+EN + + LE ++ +++ E E A + DE++++L V ++L A
Sbjct: 428 IEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDA 487
Query: 180 E-DRVKSG-DAKISELEEELK 198
DR +S + +E+ E +K
Sbjct: 488 RIDRQESSRQQRKAEIMESIK 508
Score = 50.0 bits (114), Expect = 9e-06
Identities = 65/291 (22%), Positives = 129/291 (44%), Gaps = 37/291 (12%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAE------KV--NE-EVRELQKKLAQVEE 55
KK + A + E ++AD Q+ +D +RA+ K+ NE E+ +L K+LA +
Sbjct: 189 KKNIAAERKEAKQEKEEADRY-QRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNK 247
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-------KSEERSGT 108
++ +K ++++ +L+EK+K+L E + +++++ + +L K++E +
Sbjct: 248 EIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSH 307
Query: 109 AQQKLLEAQQS--------------ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 154
+KL A++S DE + +E Q+ EERM++ + L
Sbjct: 308 KIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTL 367
Query: 155 AEDADGK----SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVS 210
E+ K +E S++ A + ELE +R + D +LEE KV + ++
Sbjct: 368 EENQVKKYHRLKEEASKRAATLAQELE-KFNRDQKADQDRLDLEERKKVETEAKIKQKLR 426
Query: 211 EEKANQ-RVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
E + NQ R+E+ + V+ ++ +D + EL
Sbjct: 427 EIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKEL 477
Score = 40.7 bits (91), Expect = 0.006
Identities = 50/222 (22%), Positives = 96/222 (43%), Gaps = 27/222 (12%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-------VRELQKKLAQVEED 56
I+ + +L++D DK EQ + EK+ +E + E +L ++
Sbjct: 819 IQLDFEKNQLKEDQ--DKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQ 876
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+ K+++ N ++EE K+L E+ L ++V IE LE ++RS + LL+A
Sbjct: 877 HLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLE--QKRSD--RHNLLQA 932
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
CK+ + + + MD ++ + E ED+ S +S + + L
Sbjct: 933 ----------CKMQDIKLPLSKGTMDDISQE--EGSSQGEDSVSGSQRISS--IYAREAL 978
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
+ D K ++ EEE+K N+L+ ++ QR+
Sbjct: 979 IEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRI 1020
Score = 33.5 bits (73), Expect = 0.86
Identities = 28/162 (17%), Positives = 75/162 (46%), Gaps = 10/162 (6%)
Query: 26 EQQARDANLRAEKVNEEV-----RELQ-KKLAQVEEDLILNKNKLEQANKDLEEKEK--- 76
E++ +D + +V +EV RE+ + + + EE+ + +N++ + + E ++
Sbjct: 759 EREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLG 818
Query: 77 -QLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 135
QL + ++ KV E+ ++K E +++ + DE + L+N+
Sbjct: 819 IQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHL 878
Query: 136 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
+ ++ ++++E R A+ + + +++ +E +LE
Sbjct: 879 AKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLE 920
Score = 32.7 bits (71), Expect = 1.5
Identities = 45/217 (20%), Positives = 89/217 (41%), Gaps = 21/217 (9%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-------AQV 53
++ +KK+ Q D M + + Q N E+ E++KKL +
Sbjct: 849 IEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHL 908
Query: 54 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI--EEDLEKSEER-SGTAQ 110
++++ + KLEQ D + + ++ + I EE + E+ SG+ +
Sbjct: 909 QKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGSSQGEDSVSGSQR 968
Query: 111 QKLLEAQQSADE--NNRMCKVLENRAQQDE--ERMDQLTNQLKE-----ARLLAED--AD 159
+ A+++ E +C+ L++ ++E + M+ L +L E R+ A + A
Sbjct: 969 ISSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAM 1028
Query: 160 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 196
K + V K DE E A R K ++++E
Sbjct: 1029 EKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKE 1065
Score = 31.5 bits (68), Expect = 3.5
Identities = 26/132 (19%), Positives = 55/132 (41%), Gaps = 3/132 (2%)
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
E+ KDL+EK Q+ E V+ I E E+ +R +K LE +
Sbjct: 759 EREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLG 818
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
+N+ ++D++++ +K+ + + E R + +++ + +D
Sbjct: 819 IQLDFEKNQLKEDQDKVHMWEQTVKKDE---NEIEKLKKEEQRHMKIIDETMAQLQDLKN 875
Query: 185 SGDAKISELEEE 196
AK SE+ ++
Sbjct: 876 QHLAKKSEVNDK 887
>BC064368-1|AAH64368.1| 847|Homo sapiens SMC1A protein protein.
Length = 847
Score = 57.6 bits (133), Expect = 5e-08
Identities = 42/159 (26%), Positives = 86/159 (54%), Gaps = 8/159 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQ-QARDANLRAEKVNEEVR---ELQKKLAQVEED 56
MD ++K+M +++ + ++ + Q Q RD L +V + R E K+ A + ++
Sbjct: 333 MDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQE 392
Query: 57 LI-LNKN-KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
L N++ K +Q DLEE++K TEA++ R++++ ++ +EK EE T++Q L
Sbjct: 393 LEKFNRDQKADQDRLDLEERKK--VETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLE 450
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 153
E ++ E ++ + R + + ++Q+ QL +AR+
Sbjct: 451 EQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARI 489
Score = 53.6 bits (123), Expect = 8e-07
Identities = 44/201 (21%), Positives = 93/201 (46%), Gaps = 7/201 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE-EDLIL 59
++A KK +Q + D E++ L EK +E E ++ +Q + DL L
Sbjct: 312 LEAAKKSLQNAQKHYKKRKGDMDELEKEM----LSVEKARQEFEERMEEESQSQGRDLTL 367
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
+N++++ ++ EE K+ E+ NR + ++ L+ E + + K+ + +
Sbjct: 368 EENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLRE 427
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+EN + + LE ++ +++ E E A + DE++++L V ++L A
Sbjct: 428 IEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDA 487
Query: 180 E-DRVKSG-DAKISELEEELK 198
DR +S + +E+ E +K
Sbjct: 488 RIDRQESSRQQRKAEIMESIK 508
Score = 50.0 bits (114), Expect = 9e-06
Identities = 65/291 (22%), Positives = 129/291 (44%), Gaps = 37/291 (12%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAE------KV--NE-EVRELQKKLAQVEE 55
KK + A + E ++AD Q+ +D +RA+ K+ NE E+ +L K+LA +
Sbjct: 189 KKNIAAERKEAKQEKEEADRY-QRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNK 247
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-------KSEERSGT 108
++ +K ++++ +L+EK+K+L E + +++++ + +L K++E +
Sbjct: 248 EIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSH 307
Query: 109 AQQKLLEAQQS--------------ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 154
+KL A++S DE + +E Q+ EERM++ + L
Sbjct: 308 KIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTL 367
Query: 155 AEDADGK----SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVS 210
E+ K +E S++ A + ELE +R + D +LEE KV + ++
Sbjct: 368 EENQVKKYHRLKEEASKRAATLAQELE-KFNRDQKADQDRLDLEERKKVETEAKIKQKLR 426
Query: 211 EEKANQ-RVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
E + NQ R+E+ + V+ ++ +D + EL
Sbjct: 427 EIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKEL 477
>AL161779-1|CAI42089.1| 1233|Homo sapiens structural maintenance of
chromosomes 1A protein.
Length = 1233
Score = 57.6 bits (133), Expect = 5e-08
Identities = 42/159 (26%), Positives = 86/159 (54%), Gaps = 8/159 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQ-QARDANLRAEKVNEEVR---ELQKKLAQVEED 56
MD ++K+M +++ + ++ + Q Q RD L +V + R E K+ A + ++
Sbjct: 333 MDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQE 392
Query: 57 LI-LNKN-KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
L N++ K +Q DLEE++K TEA++ R++++ ++ +EK EE T++Q L
Sbjct: 393 LEKFNRDQKADQDRLDLEERKK--VETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLE 450
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 153
E ++ E ++ + R + + ++Q+ QL +AR+
Sbjct: 451 EQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARI 489
Score = 53.6 bits (123), Expect = 8e-07
Identities = 44/201 (21%), Positives = 93/201 (46%), Gaps = 7/201 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE-EDLIL 59
++A KK +Q + D E++ L EK +E E ++ +Q + DL L
Sbjct: 312 LEAAKKSLQNAQKHYKKRKGDMDELEKEM----LSVEKARQEFEERMEEESQSQGRDLTL 367
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
+N++++ ++ EE K+ E+ NR + ++ L+ E + + K+ + +
Sbjct: 368 EENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLRE 427
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+EN + + LE ++ +++ E E A + DE++++L V ++L A
Sbjct: 428 IEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDA 487
Query: 180 E-DRVKSG-DAKISELEEELK 198
DR +S + +E+ E +K
Sbjct: 488 RIDRQESSRQQRKAEIMESIK 508
Score = 50.0 bits (114), Expect = 9e-06
Identities = 65/291 (22%), Positives = 129/291 (44%), Gaps = 37/291 (12%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAE------KV--NE-EVRELQKKLAQVEE 55
KK + A + E ++AD Q+ +D +RA+ K+ NE E+ +L K+LA +
Sbjct: 189 KKNIAAERKEAKQEKEEADRY-QRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNK 247
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-------KSEERSGT 108
++ +K ++++ +L+EK+K+L E + +++++ + +L K++E +
Sbjct: 248 EIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSH 307
Query: 109 AQQKLLEAQQS--------------ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 154
+KL A++S DE + +E Q+ EERM++ + L
Sbjct: 308 KIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTL 367
Query: 155 AEDADGK----SDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVS 210
E+ K +E S++ A + ELE +R + D +LEE KV + ++
Sbjct: 368 EENQVKKYHRLKEEASKRAATLAQELE-KFNRDQKADQDRLDLEERKKVETEAKIKQKLR 426
Query: 211 EEKANQ-RVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
E + NQ R+E+ + V+ ++ +D + EL
Sbjct: 427 EIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKEL 477
Score = 40.7 bits (91), Expect = 0.006
Identities = 50/222 (22%), Positives = 96/222 (43%), Gaps = 27/222 (12%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-------VRELQKKLAQVEED 56
I+ + +L++D DK EQ + EK+ +E + E +L ++
Sbjct: 819 IQLDFEKNQLKEDQ--DKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQ 876
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+ K+++ N ++EE K+L E+ L ++V IE LE ++RS + LL+A
Sbjct: 877 HLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLE--QKRSD--RHNLLQA 932
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
CK+ + + + MD ++ + E ED+ S +S + + L
Sbjct: 933 ----------CKMQDIKLPLSKGTMDDISQE--EGSSQGEDSVSGSQRISS--IYAREAL 978
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
+ D K ++ EEE+K N+L+ ++ QR+
Sbjct: 979 IEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRI 1020
Score = 33.5 bits (73), Expect = 0.86
Identities = 28/162 (17%), Positives = 75/162 (46%), Gaps = 10/162 (6%)
Query: 26 EQQARDANLRAEKVNEEV-----RELQ-KKLAQVEEDLILNKNKLEQANKDLEEKEK--- 76
E++ +D + +V +EV RE+ + + + EE+ + +N++ + + E ++
Sbjct: 759 EREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLG 818
Query: 77 -QLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 135
QL + ++ KV E+ ++K E +++ + DE + L+N+
Sbjct: 819 IQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHL 878
Query: 136 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
+ ++ ++++E R A+ + + +++ +E +LE
Sbjct: 879 AKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLE 920
Score = 32.7 bits (71), Expect = 1.5
Identities = 45/217 (20%), Positives = 89/217 (41%), Gaps = 21/217 (9%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-------AQV 53
++ +KK+ Q D M + + Q N E+ E++KKL +
Sbjct: 849 IEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHL 908
Query: 54 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI--EEDLEKSEER-SGTAQ 110
++++ + KLEQ D + + ++ + I EE + E+ SG+ +
Sbjct: 909 QKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGSSQGEDSVSGSQR 968
Query: 111 QKLLEAQQSADE--NNRMCKVLENRAQQDE--ERMDQLTNQLKE-----ARLLAED--AD 159
+ A+++ E +C+ L++ ++E + M+ L +L E R+ A + A
Sbjct: 969 ISSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAM 1028
Query: 160 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 196
K + V K DE E A R K ++++E
Sbjct: 1029 EKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKE 1065
Score = 31.5 bits (68), Expect = 3.5
Identities = 26/132 (19%), Positives = 55/132 (41%), Gaps = 3/132 (2%)
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
E+ KDL+EK Q+ E V+ I E E+ +R +K LE +
Sbjct: 759 EREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLG 818
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
+N+ ++D++++ +K+ + + E R + +++ + +D
Sbjct: 819 IQLDFEKNQLKEDQDKVHMWEQTVKKDE---NEIEKLKKEEQRHMKIIDETMAQLQDLKN 875
Query: 185 SGDAKISELEEE 196
AK SE+ ++
Sbjct: 876 QHLAKKSEVNDK 887
>Z29064-1|CAA82305.1| 896|Homo sapiens AF-1p protein.
Length = 896
Score = 57.2 bits (132), Expect = 6e-08
Identities = 35/173 (20%), Positives = 88/173 (50%), Gaps = 14/173 (8%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+ +N E+ +LQ++ VE+DL ++ ++Q ++++ + ++ + L + QQ++
Sbjct: 336 DTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQ 395
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
E L++ +E+ +++L E ++ E ++ L+ E ++ +L +AR
Sbjct: 396 ELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAR---- 451
Query: 157 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 209
+E+SR ++ E E+ V+SG A++ L++ L+ + S+++
Sbjct: 452 ------EELSR----LQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQM 494
Score = 56.0 bits (129), Expect = 1e-07
Identities = 31/149 (20%), Positives = 73/149 (48%), Gaps = 4/149 (2%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K+K +K D D E Q + NL +K+ + +++Q+ L +++E + +
Sbjct: 356 LKEKEDTIKQRTSEVQDLQD--EVQRENTNL--QKLQAQKQQVQELLDELDEQKAQLEEQ 411
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L++ K E+ + +++ +AE+ + ++ EE+L K+ E QQ+ E ++S +
Sbjct: 412 LKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESG 471
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEAR 152
+ L+ Q ++ + + +L E +
Sbjct: 472 KAQLEPLQQHLQDSQQEISSMQMKLMEMK 500
Score = 54.4 bits (125), Expect = 4e-07
Identities = 31/144 (21%), Positives = 68/144 (47%)
Query: 76 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 135
K+L E+ L R+ +E+DL++ E+ ++ + Q N + L+ + Q
Sbjct: 333 KELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQ 392
Query: 136 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 195
Q +E +D+L Q + ++ K E ++ ++ ++ EL E ++ + + ++++ E
Sbjct: 393 QVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKARE 452
Query: 196 ELKVVGNSLKSLEVSEEKANQRVE 219
EL + LE S E ++E
Sbjct: 453 ELSRLQQETAELEESVESGKAQLE 476
Score = 46.8 bits (106), Expect = 9e-05
Identities = 34/156 (21%), Positives = 77/156 (49%), Gaps = 8/156 (5%)
Query: 1 MDAIKKKMQAMKLEKDNA----MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 56
+D + ++ ++ EK+N +K DT +Q+ + ++V E LQK AQ ++
Sbjct: 335 LDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQV 394
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
L ++L++ LEE+ K++ AE A L + ++ +L E + T +++L +A
Sbjct: 395 QEL-LDELDEQKAQLEEQLKEVRKKCAEEAQL---ISSLKAELTSQESQISTYEEELAKA 450
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
++ + LE + + +++ L L++++
Sbjct: 451 REELSRLQQETAELEESVESGKAQLEPLQQHLQDSQ 486
>Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein.
Length = 2663
Score = 57.2 bits (132), Expect = 6e-08
Identities = 49/222 (22%), Positives = 112/222 (50%), Gaps = 17/222 (7%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M + K++Q E + + D ++ ++++ E ++E+ K + EE+L +
Sbjct: 1423 MLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVA 1482
Query: 61 ----KNKLEQANK---DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
K + E N+ +L EKE +++ + ++ A+N K+Q +++ + EE+ Q +
Sbjct: 1483 HCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQLNIKQ--I 1540
Query: 114 LEAQQSADENNRMC---KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 170
E Q++ +E + K ++ Q E +M +LTN+L+E++ + + +E+ R
Sbjct: 1541 SEVQENVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKR--- 1597
Query: 171 FVEDELEVAEDRVKSGDAKI-SELEEELKVVGNSLKSLEVSE 211
V++ L++ D++K +I ++++E + LK V+E
Sbjct: 1598 -VQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNE 1638
Score = 48.8 bits (111), Expect = 2e-05
Identities = 50/197 (25%), Positives = 96/197 (48%), Gaps = 16/197 (8%)
Query: 26 EQQARDANLRAEK--VNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 83
E Q D++L A K ++ + +ELQ+K +V+E L N++EQ + LE ++ L E
Sbjct: 853 EAQKFDSSLGALKTELSYKTQELQEKTREVQERL----NEMEQLKEQLENRDSPLQTVER 908
Query: 84 EVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQ 143
E + K+QQ E+++ + +Q L E+ Q E +++ + + + + +Q
Sbjct: 909 EKTLITEKLQQTLEEVKTLTQEKDDLKQ-LQESLQI--ERDQLKSDIHDTVNMNIDTQEQ 965
Query: 144 LTNQLKEARLLAEDADGK----SDEVSRKLAFVEDELEVAED--RVKSGDAKISELE-EE 196
L N L+ + E + S+EVSR L E+ E ++ + G K +LE +
Sbjct: 966 LRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKN 1025
Query: 197 LKVVGNSLKSLEVSEEK 213
+ + +K E+ E++
Sbjct: 1026 TQTLTADVKDNEIIEQQ 1042
Score = 48.4 bits (110), Expect = 3e-05
Identities = 53/260 (20%), Positives = 109/260 (41%), Gaps = 17/260 (6%)
Query: 26 EQQARDANLRAE--KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 83
+ + A LR+E ++ E+++EL Q+E D+ L +++LE K + EK+L +
Sbjct: 636 DAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFN 695
Query: 84 EVAALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE-RM 141
E+ L + ++ +DL + E G K+ + Q+ ++ +V EN A ++E +
Sbjct: 696 EITKLTSLIDGKVPKDLLCNLELEG----KITDLQKELNK-----EVEENEALREEVILL 746
Query: 142 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 201
+L + E L ++ KS+E L + E + V ++++ L EE+
Sbjct: 747 SELKSLPSEVERLRKEIQDKSEE----LHIITSEKDKLFSEVVHKESRVQGLLEEIGKTK 802
Query: 202 NSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELG 261
+ L + + + + +Q + F + + L KE + + LG
Sbjct: 803 DDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLG 862
Query: 262 INKDRYKSLADEMDSTFAEL 281
K E+ E+
Sbjct: 863 ALKTELSYKTQELQEKTREV 882
Score = 48.4 bits (110), Expect = 3e-05
Identities = 53/286 (18%), Positives = 133/286 (46%), Gaps = 14/286 (4%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK--N 62
+++++++ E+DN + E + L+ E + E + ++Q+ ++ E+ L + + N
Sbjct: 1341 QEEIKSLTKERDNLKTIKEALE--VKHDQLK-EHIRETLAKIQESQSKQEQSLNMKEKDN 1397
Query: 63 KLEQANKDLEE---KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
+ + ++E+ K+ L E E+ L++++Q+ +++ KS + Q+L E QS
Sbjct: 1398 ETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEM-KSVAKEKDDLQRLQEVLQS 1456
Query: 120 -ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
+D+ K + + + EE + LKE + E +++ ++ +LE
Sbjct: 1457 ESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEA 1516
Query: 179 AEDRVKSGDAKISELEEEL--KVVGNSLKSL-EVSEEKANQRVEEFX-XXXXXXXXXXXX 234
D++++ +I E EE+L K + +++ E+ + K +++ ++
Sbjct: 1517 INDKLQNKIQEIYEKEEQLNIKQISEVQENVNELKQFKEHRKAKDSALQSIESKMLELTN 1576
Query: 235 XXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
+ + K ++E+ R+++ L I +D+ K E+ + E
Sbjct: 1577 RLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKE 1622
Score = 47.2 bits (107), Expect = 7e-05
Identities = 41/217 (18%), Positives = 107/217 (49%), Gaps = 12/217 (5%)
Query: 10 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
A+K + ++ ++ +K+ V E KL+ +++DL + KL++ +
Sbjct: 1764 ALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQ 1823
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE----AQQSADENNR 125
+L+ E QL + +V +KV ++E+ ++ +++S T + +E AQ+ +
Sbjct: 1824 ELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQELHENLEE 1883
Query: 126 MCKVLENR--AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
M V++ R ++ EE + +QLKE+ ++ + E+ ++L + ++++
Sbjct: 1884 MKSVMKERDNLRRVEETLKLERDQLKES---LQETKARDLEIQQEL---KTARMLSKEHK 1937
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
++ D ++ E+ + + K L+ S+++ ++++E
Sbjct: 1938 ETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQE 1974
Score = 46.8 bits (106), Expect = 9e-05
Identities = 23/103 (22%), Positives = 58/103 (56%), Gaps = 1/103 (0%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D +K+ +Q K + T +++ +K+ E++ E +++ +++DL +K
Sbjct: 1906 DQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSK 1965
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 104
++L++ ++L++KE QL + +V ++K+ ++E+ L+K E
Sbjct: 1966 DELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQ-LKKQFE 2007
Score = 45.2 bits (102), Expect = 3e-04
Identities = 42/205 (20%), Positives = 97/205 (47%), Gaps = 10/205 (4%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+Q E++ +++E + + +E+L L ++L++ + + +++ E E+
Sbjct: 1056 QQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGEL 1115
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE---NRAQQDEERMD 142
+ ++ ++EE L++ ++ QQ+LL Q+ E + +E N + E ++
Sbjct: 1116 SRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLE 1175
Query: 143 QL-TNQLKEARLLAED-ADGKSDEVSRK-LAFVEDELEVAEDRVKSGDAKIS----ELEE 195
+ T +L+ A+ L E+ + KS RK L ++ E D ++ +I + +E
Sbjct: 1176 HMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKE 1235
Query: 196 ELKVVGNSLKSLEVSEEKANQRVEE 220
ELK+ LK + + ++ + V E
Sbjct: 1236 ELKIAHIHLKEHQETIDELRRSVSE 1260
Score = 43.2 bits (97), Expect = 0.001
Identities = 43/214 (20%), Positives = 99/214 (46%), Gaps = 14/214 (6%)
Query: 20 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK---LEQANKDLEEKEK 76
+K QQ ++ + V EE+ E+QKK+ ++E KNK LE + E +
Sbjct: 1127 EKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQ 1186
Query: 77 QLTATEAEVAALNRKVQQIEEDLEKS-EERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 135
+L EV ++ K +++ ++L+KS E + + E + + + K+ +
Sbjct: 1187 KLNENYEEVKSIT-KERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLK 1245
Query: 136 QDEERMDQLTNQLKE--ARLL-AEDADGKSDEVSRKLAFVEDELEVAED--RVKSGDAKI 190
+ +E +D+L + E A+++ +D + ++ ++ + +E E+ + +V +
Sbjct: 1246 EHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKKVSETQETM 1305
Query: 191 SEL----EEELKVVGNSLKSLEVSEEKANQRVEE 220
+EL E+ +L +E+ + N++ +E
Sbjct: 1306 NELELLTEQSTTKDSTTLARIEMERLRLNEKFQE 1339
Score = 39.9 bits (89), Expect = 0.010
Identities = 48/213 (22%), Positives = 104/213 (48%), Gaps = 29/213 (13%)
Query: 33 NLRAE-KVNEEVRELQKKLAQVE---EDLILNK------NKLEQANKDLEEKEKQL---T 79
NL E K+ + +EL K++ + E E++IL +++E+ K++++K ++L T
Sbjct: 715 NLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIIT 774
Query: 80 ATE----AEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 135
+ + +EV +VQ + E++ K+++ T Q Q + E + +
Sbjct: 775 SEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYK 834
Query: 136 ---QDEERMDQ-LTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS 191
++ ERM+Q + N KEA+ E+S K ++++ ++R+ ++
Sbjct: 835 MVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLN----EME 890
Query: 192 ELEEELKVVGNSLKSLE----VSEEKANQRVEE 220
+L+E+L+ + L+++E + EK Q +EE
Sbjct: 891 QLKEQLENRDSPLQTVEREKTLITEKLQQTLEE 923
Score = 39.1 bits (87), Expect = 0.017
Identities = 60/284 (21%), Positives = 115/284 (40%), Gaps = 27/284 (9%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQK-KLAQVEEDLILNKNK 63
+K+ Q +K+ N + CE + +K+N E E + +L Q+ + +
Sbjct: 1625 EKEYQFLKMTAVNETQEK-MCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRS 1683
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD-- 121
+ + DL E+ L ++ R+ I DLEK EE L E Q++ D
Sbjct: 1684 VTKERDDLRSVEETLKVERDQLKENLRET--ITRDLEKQEELK-IVHMHLKEHQETIDKL 1740
Query: 122 ---------ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 172
E + M K LE+ + + ++ +L+ A + ++ D++ ++
Sbjct: 1741 RGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEK 1800
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXX 232
D+L + +++ +AK+ E +ELK + L +L+ + ++V E
Sbjct: 1801 TDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQS 1860
Query: 233 XXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDS 276
T+ KL+ E L EL N + KS+ E D+
Sbjct: 1861 L-----------TLSKLEIENLNLAQELHENLEEMKSVMKERDN 1893
Score = 38.3 bits (85), Expect = 0.030
Identities = 32/156 (20%), Positives = 73/156 (46%), Gaps = 7/156 (4%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
E++N+E+ L K+ + + L K +L ++L+EK +++ E+ L +++ +
Sbjct: 841 ERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRD 900
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
L+ E +KL QQ+ +E + + ++ +Q +E + +QLK
Sbjct: 901 SPLQTVEREKTLITEKL---QQTLEEVKTLTQEKDD-LKQLQESLQIERDQLKSD---IH 953
Query: 157 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 192
D + + +L + L+ ++ + + +KISE
Sbjct: 954 DTVNMNIDTQEQLRNALESLKQHQETINTLKSKISE 989
Score = 38.3 bits (85), Expect = 0.030
Identities = 45/229 (19%), Positives = 98/229 (42%), Gaps = 13/229 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL------QKKLAQVE 54
M ++KK+ ++ K+ +K T E + A+K+NE E+ +K L +++
Sbjct: 1150 MSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQ 1209
Query: 55 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV-QQIEEDLEKSEERSGTAQQKL 113
+ ++ L +++E Q T E ++A ++ K Q+ ++L +S
Sbjct: 1210 KSFETERDHLRGYIREIEATGLQ-TKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINT 1268
Query: 114 LEAQQSADENNRMCKVL--ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
+ ++S + VL E + +++ + + E LL E + K S LA
Sbjct: 1269 QDLEKSHTKLQEEIPVLHEEQELLPNVKKVSETQETMNELELLTEQSTTKD---STTLAR 1325
Query: 172 VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+E E ++ + +I L +E + ++LEV ++ + + E
Sbjct: 1326 IEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRE 1374
Score = 36.7 bits (81), Expect = 0.092
Identities = 38/224 (16%), Positives = 103/224 (45%), Gaps = 14/224 (6%)
Query: 6 KKMQAMKLEKDNAMD-------KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 58
++M+++ E+DN + D ++ ++ R ++ +E++ + + +E +
Sbjct: 1882 EEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVD 1941
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
+ K+ + + + +K L ++ E+ +++Q+ E L + +E + +K+ E +Q
Sbjct: 1942 KLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQ 2001
Query: 119 --SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
E N +CK + Q + +L L+E R++A++ D + + L D+
Sbjct: 2002 LKKQFEPNYLCKCEMDNFQLTK----KLHESLEEIRIVAKERD-ELRRIKESLKMERDQF 2056
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ + D + +++ E +++ + + L S + R++E
Sbjct: 2057 IATLREMIARDRQNHQVKPEKRLLSDGQQHLMESLREKCSRIKE 2100
Score = 35.1 bits (77), Expect = 0.28
Identities = 29/160 (18%), Positives = 67/160 (41%), Gaps = 1/160 (0%)
Query: 40 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 99
N + + + + EE + EQ K L+EK ++L + Q+
Sbjct: 2266 NNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTT 2325
Query: 100 EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 159
+ ++ T++ L ++ + N + + E+ A E ++ ++ +L+ +
Sbjct: 2326 QDNKNPHVTSRATQLTTEKIRELENSLHEAKES-AMHKESKIIKMQKELEVTNDIIAKLQ 2384
Query: 160 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKV 199
K E ++ L ++ ++V +D+V G E E+LK+
Sbjct: 2385 AKVHESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDLKM 2424
Score = 34.7 bits (76), Expect = 0.37
Identities = 37/174 (21%), Positives = 76/174 (43%), Gaps = 15/174 (8%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
EK+ +++ ++ QV N + N+ E +E+ T ++ + ++ ++
Sbjct: 2245 EKLKNGIQKENDRICQVNN--FFNNRIIAIMNESTEFEERSATISKE----WEQDLKSLK 2298
Query: 97 EDLEKSEERSGTAQQKLLEAQQ--SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 154
E EK + T + L Q ++N+ V Q E++ +L N L EA+
Sbjct: 2299 EKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAK-- 2356
Query: 155 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
E A K ++ + ++ ELEV D + AK+ E + L+ +++ L+
Sbjct: 2357 -ESAMHKESKIIK----MQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQ 2405
Score = 31.5 bits (68), Expect = 3.5
Identities = 34/179 (18%), Positives = 82/179 (45%), Gaps = 6/179 (3%)
Query: 5 KKKMQAMKLEKD--NAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE-DLILNK 61
+K +Q ++KD + D+ Q+ + L+ +V E+V KK+ ++E+
Sbjct: 1949 EKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEP 2008
Query: 62 NKLEQANKDLEEKEKQL--TATEAEVAALNR-KVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
N L + D + K+L + E + A R ++++I+E L+ ++ ++++ +
Sbjct: 2009 NYLCKCEMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDR 2068
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
+ ++L + Q E + + +++KE + D + ++R +E E+E
Sbjct: 2069 QNHQVKPEKRLLSDGQQHLMESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIE 2127
>U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein.
Length = 1017
Score = 57.2 bits (132), Expect = 6e-08
Identities = 48/278 (17%), Positives = 123/278 (44%), Gaps = 11/278 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D +K +++ ++ E + A + +A ++ E + ++ + + L +E D++ +
Sbjct: 235 DLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIR 294
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ E +L++++++++ E ++ +Q+ E++ + +E+S TA + L +S+
Sbjct: 295 SEKEDLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKSSM 354
Query: 122 ENNRMCKVLENRAQQDEERMDQLTN--QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
+ C + + E+ + +L++A+LL DE ++ +
Sbjct: 355 REWQPCIMTKKPVSAKEQNLSSQVECLELEKAQLLQG-----LDEAKNNYIVLQSSVNGL 409
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
V+ G K+ + +EE+ + N ++ E K +Q E
Sbjct: 410 IQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELE 469
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDST 277
+ ++ LQ + L+D L + + YK+L +E++ T
Sbjct: 470 ----QKIQVLQSKNASLQDTLEVLQSSYKNLENELELT 503
Score = 56.0 bits (129), Expect = 1e-07
Identities = 39/218 (17%), Positives = 97/218 (44%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D++K K++ ++ E + + + A ++ E + ++ E+ + L E DL+ +
Sbjct: 53 DSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 112
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
++ E K ++EK+ QL+ + +++ ++++ E+ + +E S TA + L + +
Sbjct: 113 SEKENLTKQIQEKQGQLSELDKLLSSFKSQLEEKEQAEIQIKEESKTAVEMLQNQLKELN 172
Query: 122 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E + + E+ +D + + R E + + +K V +L+ +E
Sbjct: 173 EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEH 232
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
++ LE EL++ + + + E + VE
Sbjct: 233 HADLLKGRVENLERELEIARTNQEHAALEAENSKGEVE 270
Score = 43.6 bits (98), Expect = 8e-04
Identities = 40/217 (18%), Positives = 88/217 (40%), Gaps = 7/217 (3%)
Query: 11 MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKD 70
++ EK+N + + Q + + ++ E ++ Q++E+ L+ K+
Sbjct: 111 LRSEKENLTKQIQEKQGQLSELDKLLSSFKSQLEEKEQAEIQIKEESKTAVEMLQNQLKE 170
Query: 71 LEEK-------EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L E ++ + ATE + + Q+ +EK R ++K L Q E+
Sbjct: 171 LNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKES 230
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
+L+ R + E ++ + A L AE++ G+ + + K+ + L E V
Sbjct: 231 EHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDV 290
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ ++ +L EL+ + LE+ ++E
Sbjct: 291 VTIRSEKEDLTNELQKEQERISELEIINSSFENILQE 327
Score = 41.9 bits (94), Expect = 0.002
Identities = 54/257 (21%), Positives = 110/257 (42%), Gaps = 24/257 (9%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE----------EKE 75
EQ NL E + ++++ LQ K A +++ L + ++ + +LE EK
Sbjct: 456 EQNLELRNLTVE-LEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKV 514
Query: 76 KQLTATEAEVAA----LNRKVQQIEEDLEKSEER-SGTAQQKLLEAQQSAD-------EN 123
++TA E E+ + +K +++E+L + R +G Q L E + S D EN
Sbjct: 515 NKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLEN 574
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL-AFVEDELEVAEDR 182
+ + K L+ + E+ ++ ++ E +L +A+ K + E E++ ++
Sbjct: 575 SELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREK 634
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXX 242
+ S + +S + E+ ++ +S + L S + Q +EE
Sbjct: 635 LTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERA 694
Query: 243 XKTVKKLQKEVDRLEDE 259
+K L K +LE+E
Sbjct: 695 QGKMKLLIKSCKQLEEE 711
Score = 37.5 bits (83), Expect = 0.053
Identities = 40/176 (22%), Positives = 84/176 (47%), Gaps = 15/176 (8%)
Query: 41 EEVRELQKKLAQVEEDL-ILNKNKLEQANKDLEE-KEKQLTATEAEVAALNRKVQQIEED 98
++++EL + +++++ L ++K+++E+ K EE E QL EAE +K Q + D
Sbjct: 565 DQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAE-----KKHQALLLD 619
Query: 99 LEKSEE-RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 157
K E T ++KL ++ +L++ ++ L N LK + E+
Sbjct: 620 TNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEE-------LNNSLKATTQILEE 672
Query: 158 ADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
+ + + ++ E E A+ ++K +LEEE +++ L L+ ++EK
Sbjct: 673 LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEK 728
Score = 37.1 bits (82), Expect = 0.070
Identities = 39/181 (21%), Positives = 87/181 (48%), Gaps = 17/181 (9%)
Query: 34 LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 93
LR EEV +L++ + ++ + ++ K + L+E++ E +L KV+
Sbjct: 8 LRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERD-------GENDSLKDKVE 60
Query: 94 QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE-RMDQLTNQLKEAR 152
+E +L+ SEE + +L+A+ S E + +E A+ + +D +T + ++
Sbjct: 61 NLERELQMSEENQ---ELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKEN 117
Query: 153 LL--AEDADGKSDEVSRKLAFVEDEL---EVAEDRVK-SGDAKISELEEELKVVGNSLKS 206
L ++ G+ E+ + L+ + +L E AE ++K + L+ +LK + ++ +
Sbjct: 118 LTKQIQEKQGQLSELDKLLSSFKSQLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAA 177
Query: 207 L 207
L
Sbjct: 178 L 178
Score = 35.1 bits (77), Expect = 0.28
Identities = 21/98 (21%), Positives = 46/98 (46%)
Query: 112 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
+L Q+ + R + L R + DE++ + +LKE + K + + R+L
Sbjct: 9 RLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERDGENDSLKDKVENLERELQM 68
Query: 172 VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 209
E+ E+ ++ A++ L+ +++ + SLK E+
Sbjct: 69 SEENQELVILDAENSKAEVETLKTQIEEMARSLKVFEL 106
Score = 35.1 bits (77), Expect = 0.28
Identities = 47/276 (17%), Positives = 115/276 (41%), Gaps = 10/276 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ +++ K++K + ++K + + + ++ ++ ELQ++L+ + L
Sbjct: 496 LENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQL 555
Query: 64 LEQANKDLEEKEKQLTATEAEV-AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS--- 119
L + K +++ K+LT +E+ +L+ + E K E Q +L EA++
Sbjct: 556 LLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQA 615
Query: 120 --ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
D N + ++ ++ + + L++Q E LL + ++ + +E+ +
Sbjct: 616 LLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKK 675
Query: 178 VAEDRVKSGDAKISELEE---ELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXX 234
D +K + E E ++K++ S K LE +E + + +
Sbjct: 676 TKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVM 735
Query: 235 XXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSL 270
+ +K+L++ ++ E D+Y SL
Sbjct: 736 DTKVDELTTE-IKELKETLEEKTKEADEYLDKYCSL 770
Score = 33.5 bits (73), Expect = 0.86
Identities = 49/225 (21%), Positives = 93/225 (41%), Gaps = 19/225 (8%)
Query: 6 KKMQAMKLEKDNAMDKADTCE-QQARDANLRAEKVNEEVRELQKKLAQV---EEDLIL-- 59
+K++A +LE D +K C QQ +++ A+ + V L+++L +E L
Sbjct: 207 EKLRA-RLEAD---EKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEA 262
Query: 60 --NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
+K ++E +E + L E +V + + + + +L+K +ER LE
Sbjct: 263 ENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKEDLTNELQKEQERISE-----LEII 317
Query: 118 QSADENNRMCKVLE--NRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 175
S+ EN K E ++ M+ L QLK + + VS K + +
Sbjct: 318 NSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKSSMREWQPCIMTKKPVSAKEQNLSSQ 377
Query: 176 LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+E E + E + V+ +S+ L E Q++E+
Sbjct: 378 VECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEK 422
Score = 32.7 bits (71), Expect = 1.5
Identities = 57/269 (21%), Positives = 103/269 (38%), Gaps = 25/269 (9%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
++K+Q MK + AM+ T + + + V ++ L+ E L L K +L
Sbjct: 330 QEKVQ-MKEKSSTAMEMLQTQLKSSMREWQPCIMTKKPVSAKEQNLSSQVECLELEKAQL 388
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
Q L+E + ++ V L ++V+ ++ LEK +E + ++ + +Q
Sbjct: 389 LQG---LDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQ------ 439
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
L ++ Q E Q E R L + + K + K A ++D LEV + K
Sbjct: 440 -----LVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYK 494
Query: 185 SGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXK 244
+ LE EL++ S EK N+ +
Sbjct: 495 N-------LENELELTKMDKMSF---VEKVNKMTAKETELQREMHEMAQKTAELQEELSG 544
Query: 245 TVKKLQKEVDRLEDELGINKDRYKSLADE 273
+L E+ L +E+ +KD+ K L E
Sbjct: 545 EKNRLAGELQLLLEEIKSSKDQLKELTLE 573
Score = 31.1 bits (67), Expect = 4.6
Identities = 23/134 (17%), Positives = 55/134 (41%)
Query: 133 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 192
R +E + QL +++ R+ E + K ++ KL + E + +D+V++ + ++
Sbjct: 9 RLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERDGENDSLKDKVENLERELQM 68
Query: 193 LEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKE 252
EE ++V ++ + E ++EE K +++ Q +
Sbjct: 69 SEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQ 128
Query: 253 VDRLEDELGINKDR 266
+ L+ L K +
Sbjct: 129 LSELDKLLSSFKSQ 142
>U07707-1|AAA52101.1| 896|Homo sapiens epidermal growth factor
receptor substrate protein.
Length = 896
Score = 57.2 bits (132), Expect = 6e-08
Identities = 35/173 (20%), Positives = 88/173 (50%), Gaps = 14/173 (8%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+ +N E+ +LQ++ VE+DL ++ ++Q ++++ + ++ + L + QQ++
Sbjct: 336 DTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQ 395
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
E L++ +E+ +++L E ++ E ++ L+ E ++ +L +AR
Sbjct: 396 ELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAR---- 451
Query: 157 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 209
+E+SR ++ E E+ V+SG A++ L++ L+ + S+++
Sbjct: 452 ------EELSR----LQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQM 494
Score = 56.0 bits (129), Expect = 1e-07
Identities = 31/149 (20%), Positives = 73/149 (48%), Gaps = 4/149 (2%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K+K +K D D E Q + NL +K+ + +++Q+ L +++E + +
Sbjct: 356 LKEKEDTIKQRTSEVQDLQD--EVQRENTNL--QKLQAQKQQVQELLDELDEQKAQLEEQ 411
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L++ K E+ + +++ +AE+ + ++ EE+L K+ E QQ+ E ++S +
Sbjct: 412 LKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESG 471
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEAR 152
+ L+ Q ++ + + +L E +
Sbjct: 472 KAQLEPLQQHLQDSQQEISSMQMKLMEMK 500
Score = 54.4 bits (125), Expect = 4e-07
Identities = 31/144 (21%), Positives = 68/144 (47%)
Query: 76 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 135
K+L E+ L R+ +E+DL++ E+ ++ + Q N + L+ + Q
Sbjct: 333 KELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQ 392
Query: 136 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 195
Q +E +D+L Q + ++ K E ++ ++ ++ EL E ++ + + ++++ E
Sbjct: 393 QVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKARE 452
Query: 196 ELKVVGNSLKSLEVSEEKANQRVE 219
EL + LE S E ++E
Sbjct: 453 ELSRLQQETAELEESVESGKAQLE 476
Score = 46.8 bits (106), Expect = 9e-05
Identities = 34/156 (21%), Positives = 77/156 (49%), Gaps = 8/156 (5%)
Query: 1 MDAIKKKMQAMKLEKDNA----MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 56
+D + ++ ++ EK+N +K DT +Q+ + ++V E LQK AQ ++
Sbjct: 335 LDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQV 394
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
L ++L++ LEE+ K++ AE A L + ++ +L E + T +++L +A
Sbjct: 395 QEL-LDELDEQKAQLEEQLKEVRKKCAEEAQL---ISSLKAELTSQESQISTYEEELAKA 450
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
++ + LE + + +++ L L++++
Sbjct: 451 REELSRLQQETAELEESVESGKAQLEPLQQHLQDSQ 486
>DQ367924-1|ABD34786.1| 896|Homo sapiens epidermal growth factor
receptor pathway substrate 15 protein.
Length = 896
Score = 57.2 bits (132), Expect = 6e-08
Identities = 35/173 (20%), Positives = 88/173 (50%), Gaps = 14/173 (8%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+ +N E+ +LQ++ VE+DL ++ ++Q ++++ + ++ + L + QQ++
Sbjct: 336 DTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQ 395
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
E L++ +E+ +++L E ++ E ++ L+ E ++ +L +AR
Sbjct: 396 ELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAR---- 451
Query: 157 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 209
+E+SR ++ E E+ V+SG A++ L++ L+ + S+++
Sbjct: 452 ------EELSR----LQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQM 494
Score = 56.0 bits (129), Expect = 1e-07
Identities = 31/149 (20%), Positives = 73/149 (48%), Gaps = 4/149 (2%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K+K +K D D E Q + NL +K+ + +++Q+ L +++E + +
Sbjct: 356 LKEKEDTIKQRTSEVQDLQD--EVQRENTNL--QKLQAQKQQVQELLDELDEQKAQLEEQ 411
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L++ K E+ + +++ +AE+ + ++ EE+L K+ E QQ+ E ++S +
Sbjct: 412 LKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESG 471
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEAR 152
+ L+ Q ++ + + +L E +
Sbjct: 472 KAQLEPLQQHLQDSQQEISSMQMKLMEMK 500
Score = 54.4 bits (125), Expect = 4e-07
Identities = 31/144 (21%), Positives = 68/144 (47%)
Query: 76 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 135
K+L E+ L R+ +E+DL++ E+ ++ + Q N + L+ + Q
Sbjct: 333 KELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQ 392
Query: 136 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 195
Q +E +D+L Q + ++ K E ++ ++ ++ EL E ++ + + ++++ E
Sbjct: 393 QVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKARE 452
Query: 196 ELKVVGNSLKSLEVSEEKANQRVE 219
EL + LE S E ++E
Sbjct: 453 ELSRLQQETAELEESVESGKAQLE 476
Score = 46.8 bits (106), Expect = 9e-05
Identities = 34/156 (21%), Positives = 77/156 (49%), Gaps = 8/156 (5%)
Query: 1 MDAIKKKMQAMKLEKDNA----MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 56
+D + ++ ++ EK+N +K DT +Q+ + ++V E LQK AQ ++
Sbjct: 335 LDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQV 394
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
L ++L++ LEE+ K++ AE A L + ++ +L E + T +++L +A
Sbjct: 395 QEL-LDELDEQKAQLEEQLKEVRKKCAEEAQL---ISSLKAELTSQESQISTYEEELAKA 450
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
++ + LE + + +++ L L++++
Sbjct: 451 REELSRLQQETAELEESVESGKAQLEPLQQHLQDSQ 486
>BC033088-1|AAH33088.1| 465|Homo sapiens LMNA protein protein.
Length = 465
Score = 57.2 bits (132), Expect = 6e-08
Identities = 67/276 (24%), Positives = 109/276 (39%), Gaps = 11/276 (3%)
Query: 10 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
A + E +A D+ ++ L KV EE +EL+ + E DLI + +L+
Sbjct: 80 AYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKACNTKKEGDLIAAQARLKDLEA 139
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL-EAQQSADENNRMCK 128
L KE L+ +E L ++ + + K E G A+++L E + D NR+
Sbjct: 140 LLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQT 199
Query: 129 VLENRAQQDEERMDQL--TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA-EDRVKS 185
+ E Q ++L T + E RL+ D +GK E +LA EL ED+V+
Sbjct: 200 MKEELDFQKNIYSEELRETKRRHETRLVEID-NGKQREFESRLADALQELRAQHEDQVEQ 258
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKT 245
ELE K L + S E+ + V K
Sbjct: 259 YK---KELE---KTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQ 312
Query: 246 VKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ + ++ LED L +D + L E + AE+
Sbjct: 313 LAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEM 348
>AL671986-11|CAI13030.1| 896|Homo sapiens epidermal growth factor
receptor pathway substrate 15 protein.
Length = 896
Score = 57.2 bits (132), Expect = 6e-08
Identities = 35/173 (20%), Positives = 88/173 (50%), Gaps = 14/173 (8%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+ +N E+ +LQ++ VE+DL ++ ++Q ++++ + ++ + L + QQ++
Sbjct: 336 DTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQ 395
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
E L++ +E+ +++L E ++ E ++ L+ E ++ +L +AR
Sbjct: 396 ELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAR---- 451
Query: 157 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 209
+E+SR ++ E E+ V+SG A++ L++ L+ + S+++
Sbjct: 452 ------EELSR----LQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQM 494
Score = 56.0 bits (129), Expect = 1e-07
Identities = 31/149 (20%), Positives = 73/149 (48%), Gaps = 4/149 (2%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K+K +K D D E Q + NL +K+ + +++Q+ L +++E + +
Sbjct: 356 LKEKEDTIKQRTSEVQDLQD--EVQRENTNL--QKLQAQKQQVQELLDELDEQKAQLEEQ 411
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L++ K E+ + +++ +AE+ + ++ EE+L K+ E QQ+ E ++S +
Sbjct: 412 LKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESG 471
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEAR 152
+ L+ Q ++ + + +L E +
Sbjct: 472 KAQLEPLQQHLQDSQQEISSMQMKLMEMK 500
Score = 54.4 bits (125), Expect = 4e-07
Identities = 31/144 (21%), Positives = 68/144 (47%)
Query: 76 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 135
K+L E+ L R+ +E+DL++ E+ ++ + Q N + L+ + Q
Sbjct: 333 KELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQ 392
Query: 136 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 195
Q +E +D+L Q + ++ K E ++ ++ ++ EL E ++ + + ++++ E
Sbjct: 393 QVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKARE 452
Query: 196 ELKVVGNSLKSLEVSEEKANQRVE 219
EL + LE S E ++E
Sbjct: 453 ELSRLQQETAELEESVESGKAQLE 476
Score = 46.8 bits (106), Expect = 9e-05
Identities = 34/156 (21%), Positives = 77/156 (49%), Gaps = 8/156 (5%)
Query: 1 MDAIKKKMQAMKLEKDNA----MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 56
+D + ++ ++ EK+N +K DT +Q+ + ++V E LQK AQ ++
Sbjct: 335 LDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQV 394
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
L ++L++ LEE+ K++ AE A L + ++ +L E + T +++L +A
Sbjct: 395 QEL-LDELDEQKAQLEEQLKEVRKKCAEEAQL---ISSLKAELTSQESQISTYEEELAKA 450
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
++ + LE + + +++ L L++++
Sbjct: 451 REELSRLQQETAELEESVESGKAQLEPLQQHLQDSQ 486
>AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein
protein.
Length = 2585
Score = 57.2 bits (132), Expect = 6e-08
Identities = 49/220 (22%), Positives = 109/220 (49%), Gaps = 13/220 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M + K++Q E + + D ++ ++++ E ++E+ K + EE+L +
Sbjct: 1403 MLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVA 1462
Query: 61 ----KNKLEQANK---DLEEKEKQLTATEAEVAALNRKVQ-QIEEDLEKSEERSGTAQQK 112
K + E N+ +L EKE +++ + ++ A+N K+Q +I+E EK E+ + +
Sbjct: 1463 HCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISE 1522
Query: 113 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 172
+ E + K ++ Q E +M +LTN+L+E++ + + +E+ R V
Sbjct: 1523 VQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKR----V 1578
Query: 173 EDELEVAEDRVKSGDAKI-SELEEELKVVGNSLKSLEVSE 211
++ L++ D++K +I ++++E + LK V+E
Sbjct: 1579 QEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNE 1618
Score = 51.6 bits (118), Expect = 3e-06
Identities = 55/239 (23%), Positives = 112/239 (46%), Gaps = 17/239 (7%)
Query: 36 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQ----ANKDLEEKEKQLTATEAEVAALNRK 91
+EK NE + +QK L + L K+++ A+ L+E+++ + V+ K
Sbjct: 1725 SEKTNE-ISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDK 1783
Query: 92 VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA 151
+ +++DLE S + Q+K+ E + + + + K + N Q+ M+QL Q+K+
Sbjct: 1784 LSNMQKDLENSNAK---LQEKIQELKANEHQLITLKKDV-NETQKKVSEMEQLKKQIKDQ 1839
Query: 152 RLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK-SLEVS 210
L + ++ +++KL + LE + +K D + +EE LK+ + LK SL+ +
Sbjct: 1840 SLTLSKLEIENLNLAQKL---HENLEEMKSVMKERD-NLRRVEETLKLERDQLKESLQET 1895
Query: 211 EEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXX-KTVK--KLQKEVDRLEDELGINKDR 266
+ + + +E KT++ +QK++D+ +DEL +DR
Sbjct: 1896 KARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKQDR 1954
Score = 48.8 bits (111), Expect = 2e-05
Identities = 50/197 (25%), Positives = 96/197 (48%), Gaps = 16/197 (8%)
Query: 26 EQQARDANLRAEK--VNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 83
E Q D++L A K ++ + +ELQ+K +V+E L N++EQ + LE ++ L E
Sbjct: 833 EAQKFDSSLGALKTELSYKTQELQEKTREVQERL----NEMEQLKEQLENRDSTLQTVER 888
Query: 84 EVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQ 143
E + K+QQ E+++ + +Q L E+ Q E +++ + + + + +Q
Sbjct: 889 EKTLITEKLQQTLEEVKTLTQEKDDLKQ-LQESLQI--ERDQLKSDIHDTVNMNIDTQEQ 945
Query: 144 LTNQLKEARLLAEDADGK----SDEVSRKLAFVEDELEVAED--RVKSGDAKISELE-EE 196
L N L+ + E + S+EVSR L E+ E ++ + G K +LE +
Sbjct: 946 LRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKN 1005
Query: 197 LKVVGNSLKSLEVSEEK 213
+ + +K E+ E++
Sbjct: 1006 TQTLTADVKDNEIIEQQ 1022
Score = 48.4 bits (110), Expect = 3e-05
Identities = 53/260 (20%), Positives = 109/260 (41%), Gaps = 17/260 (6%)
Query: 26 EQQARDANLRAE--KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 83
+ + A LR+E ++ E+++EL Q+E D+ L +++LE K + EK+L +
Sbjct: 616 DAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFN 675
Query: 84 EVAALNRKVQ-QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE-RM 141
E+ L + ++ +DL + E G K+ + Q+ ++ +V EN A ++E +
Sbjct: 676 EITKLTSLIDGKVPKDLLCNLELEG----KITDLQKELNK-----EVEENEALREEVILL 726
Query: 142 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 201
+L + E L ++ KS+E L + E + V ++++ L EE+
Sbjct: 727 SELKSLPSEVERLRKEIQDKSEE----LHIITSEKDKLFSEVVHKESRVQGLLEEIGKTK 782
Query: 202 NSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELG 261
+ L + + + + +Q + F + + L KE + + LG
Sbjct: 783 DDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLG 842
Query: 262 INKDRYKSLADEMDSTFAEL 281
K E+ E+
Sbjct: 843 ALKTELSYKTQELQEKTREV 862
Score = 47.6 bits (108), Expect = 5e-05
Identities = 44/218 (20%), Positives = 106/218 (48%), Gaps = 15/218 (6%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK--N 62
+++++++ E+DN + E + L+ E + E + ++Q+ ++ E+ L + + N
Sbjct: 1321 QEEIKSLTKERDNLKTIKEALE--VKHDQLK-EHIRETLAKIQESQSKQEQSLNMKEKDN 1377
Query: 63 KLEQANKDLEE---KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
+ + ++E+ K+ L E E+ L++++Q+ +++ KS + Q+L E QS
Sbjct: 1378 ETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEM-KSVAKEKDDLQRLQEVLQS 1436
Query: 120 -ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
+D+ K + + + EE + LKE + E +++ ++ +LE
Sbjct: 1437 ESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEA 1496
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
D++++ +I E EE+ ++K + +EK N+
Sbjct: 1497 INDKLQNKIQEIYEKEEQF-----NIKQISEVQEKVNE 1529
Score = 46.8 bits (106), Expect = 9e-05
Identities = 45/220 (20%), Positives = 108/220 (49%), Gaps = 13/220 (5%)
Query: 10 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
A+K + ++ ++ +K+ V E KL+ +++DL + KL++ +
Sbjct: 1744 ALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQ 1803
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE----AQQSADENNR 125
+L+ E QL + +V +KV ++E+ ++ +++S T + +E AQ+ +
Sbjct: 1804 ELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEE 1863
Query: 126 MCKVLENR--AQQDEERMDQLTNQLKEA--RLLAEDADGKSD-EVSRKLAFVEDE-LEVA 179
M V++ R ++ EE + +QLKE+ A D + + + + +R L+ E ++
Sbjct: 1864 MKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKL 1923
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+++ +IS+++++L S L+ +++ N +V+
Sbjct: 1924 REKISEKTIQISDIQKDL---DKSKDELQKKQDRQNHQVK 1960
Score = 45.2 bits (102), Expect = 3e-04
Identities = 42/205 (20%), Positives = 97/205 (47%), Gaps = 10/205 (4%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
+Q E++ +++E + + +E+L L ++L++ + + +++ E E+
Sbjct: 1036 QQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGEL 1095
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE---NRAQQDEERMD 142
+ ++ ++EE L++ ++ QQ+LL Q+ E + +E N + E ++
Sbjct: 1096 SRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLE 1155
Query: 143 QL-TNQLKEARLLAED-ADGKSDEVSRK-LAFVEDELEVAEDRVKSGDAKIS----ELEE 195
+ T +L+ A+ L E+ + KS RK L ++ E D ++ +I + +E
Sbjct: 1156 HMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKE 1215
Query: 196 ELKVVGNSLKSLEVSEEKANQRVEE 220
ELK+ LK + + ++ + V E
Sbjct: 1216 ELKIAHIHLKEHQETIDELRRSVSE 1240
Score = 44.0 bits (99), Expect = 6e-04
Identities = 58/257 (22%), Positives = 108/257 (42%), Gaps = 30/257 (11%)
Query: 20 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 79
+K QQ ++ + V EE+ E+QKK+ N++E +L+ KE L
Sbjct: 1107 EKLKEKSQQLQEKQQQLLNVQEEMSEMQKKI-----------NEIENLKNELKNKELTLE 1155
Query: 80 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 139
E E L Q++ E+ E E +S T ++K+L+ Q + E R L ++ E
Sbjct: 1156 HMETERLEL---AQKLNENYE--EVKSITKERKVLKELQKSFETER--DHLRGYIREIEA 1208
Query: 140 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKV 199
Q +LK A + ++ DE+ R ++ ++ +D KS ++L+EE+ V
Sbjct: 1209 TGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSH----TKLQEEIPV 1264
Query: 200 VGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDE 259
+ E++ V+E T+ +++ E RL ++
Sbjct: 1265 LH--------EEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEK 1316
Query: 260 LGINKDRYKSLADEMDS 276
+++ KSL E D+
Sbjct: 1317 FQESQEEIKSLTKERDN 1333
Score = 40.7 bits (91), Expect = 0.006
Identities = 48/213 (22%), Positives = 105/213 (49%), Gaps = 29/213 (13%)
Query: 33 NLRAE-KVNEEVRELQKKLAQVE---EDLILNK------NKLEQANKDLEEKEKQL---T 79
NL E K+ + +EL K++ + E E++IL +++E+ K++++K ++L T
Sbjct: 695 NLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIIT 754
Query: 80 ATE----AEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 135
+ + +EV +VQ + E++ K+++ T Q Q + E + +
Sbjct: 755 SEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYK 814
Query: 136 ---QDEERMDQ-LTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS 191
++ ERM+Q + N KEA+ E+S K ++++ ++R+ ++
Sbjct: 815 MVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLN----EME 870
Query: 192 ELEEELKVVGNSLKSLE----VSEEKANQRVEE 220
+L+E+L+ ++L+++E + EK Q +EE
Sbjct: 871 QLKEQLENRDSTLQTVEREKTLITEKLQQTLEE 903
Score = 38.7 bits (86), Expect = 0.023
Identities = 48/228 (21%), Positives = 98/228 (42%), Gaps = 16/228 (7%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQK-KLAQVEEDLILNKNK 63
+K+ Q +K+ N + CE + +K+N E E + +L Q+ + +
Sbjct: 1605 EKEYQFLKMTAVNETQEK-MCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRS 1663
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD-- 121
+ + DL E+ L ++ R+ I DLEK EE L E Q++ D
Sbjct: 1664 VTKERDDLRSVEETLKVERDQLKENLRET--ITRDLEKQEELK-IVHMHLKEHQETIDKL 1720
Query: 122 ---------ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 172
E + M K LE+ + + ++ +L+ A + ++ D++ ++
Sbjct: 1721 RGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEK 1780
Query: 173 EDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
D+L + +++ +AK+ E +ELK + L +L+ + ++V E
Sbjct: 1781 TDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSE 1828
Score = 38.3 bits (85), Expect = 0.030
Identities = 32/156 (20%), Positives = 73/156 (46%), Gaps = 7/156 (4%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
E++N+E+ L K+ + + L K +L ++L+EK +++ E+ L +++ +
Sbjct: 821 ERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRD 880
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
L+ E +KL QQ+ +E + + ++ +Q +E + +QLK
Sbjct: 881 STLQTVEREKTLITEKL---QQTLEEVKTLTQEKDD-LKQLQESLQIERDQLKSD---IH 933
Query: 157 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISE 192
D + + +L + L+ ++ + + +KISE
Sbjct: 934 DTVNMNIDTQEQLRNALESLKQHQETINTLKSKISE 969
Score = 37.5 bits (83), Expect = 0.053
Identities = 45/229 (19%), Positives = 97/229 (42%), Gaps = 13/229 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL------QKKLAQVE 54
M ++KK+ ++ K+ +K T E + A+K+NE E+ +K L +++
Sbjct: 1130 MSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQ 1189
Query: 55 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV-QQIEEDLEKSEERSGTAQQKL 113
+ ++ L +++E Q T E ++A ++ K Q+ ++L +S
Sbjct: 1190 KSFETERDHLRGYIREIEATGLQ-TKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINT 1248
Query: 114 LEAQQSADENNRMCKVL--ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
+ ++S + VL E + + + + + E LL E + K S LA
Sbjct: 1249 QDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKD---STTLAR 1305
Query: 172 VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+E E ++ + +I L +E + ++LEV ++ + + E
Sbjct: 1306 IEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRE 1354
Score = 35.1 bits (77), Expect = 0.28
Identities = 29/160 (18%), Positives = 67/160 (41%), Gaps = 1/160 (0%)
Query: 40 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 99
N + + + + EE + EQ K L+EK ++L + Q+
Sbjct: 2188 NNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTT 2247
Query: 100 EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 159
+ ++ T++ L ++ + N + + E+ A E ++ ++ +L+ +
Sbjct: 2248 QDNKNPHVTSRATQLTTEKIRELENSLHEAKES-AMHKESKIIKMQKELEVTNDIIAKLQ 2306
Query: 160 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKV 199
K E ++ L ++ ++V +D+V G E E+LK+
Sbjct: 2307 AKVHESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDLKM 2346
Score = 34.7 bits (76), Expect = 0.37
Identities = 37/174 (21%), Positives = 76/174 (43%), Gaps = 15/174 (8%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
EK+ +++ ++ QV N + N+ E +E+ T ++ + ++ ++
Sbjct: 2167 EKLKNGIQKENDRICQVNN--FFNNRIIAIMNESTEFEERSATISKE----WEQDLKSLK 2220
Query: 97 EDLEKSEERSGTAQQKLLEAQQ--SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 154
E EK + T + L Q ++N+ V Q E++ +L N L EA+
Sbjct: 2221 EKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAK-- 2278
Query: 155 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
E A K ++ + ++ ELEV D + AK+ E + L+ +++ L+
Sbjct: 2279 -ESAMHKESKIIK----MQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQ 2327
Score = 31.9 bits (69), Expect = 2.6
Identities = 30/146 (20%), Positives = 69/146 (47%), Gaps = 8/146 (5%)
Query: 2 DAIKKKMQAMKLEKDNAMD-----KADTCE--QQARDANLRAEKVNEEVRELQKKLAQVE 54
D +++ + +KLE+D + KA E Q+ + A + +++ E V +L++K+++
Sbjct: 1872 DNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKT 1931
Query: 55 EDLILNKNKLEQANKDLEEK-EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
+ + L+++ +L++K ++Q + E L+ Q + E L + R ++
Sbjct: 1932 IQISDIQKDLDKSKDELQKKQDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRY 1991
Query: 114 LEAQQSADENNRMCKVLENRAQQDEE 139
E + NR+ LE + +E
Sbjct: 1992 SEMDDHYECLNRLSLDLEKEIEFQKE 2017
>X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein.
Length = 3259
Score = 56.8 bits (131), Expect = 8e-08
Identities = 50/234 (21%), Positives = 119/234 (50%), Gaps = 20/234 (8%)
Query: 4 IKKKMQAMKLE-KDNAMDKADTCE---QQARDANLRAEK-VNEEVRELQKKLAQVEEDLI 58
+KK++Q+ K K K + E +QA + +L+ +K + E++ L+++ +EE +
Sbjct: 2101 LKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIG 2160
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
+ L + +K++++ ++ L +T ++AA + + +++D ++ + + ++K +A Q
Sbjct: 2161 EIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQ 2220
Query: 119 SADENNRM----CKVLENRAQQDEERMDQLT---NQLKEARLLAEDADGKSDEVSRKLAF 171
S +E R+ C VL+++ +Q M++L ++L+ + + E ++ +K+
Sbjct: 2221 SKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCD 2280
Query: 172 --------VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 217
+ +LE S ++++LE ELK + + L L S EK ++
Sbjct: 2281 TLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQ 2334
Score = 54.8 bits (126), Expect = 3e-07
Identities = 66/298 (22%), Positives = 124/298 (41%), Gaps = 29/298 (9%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN----EEVRELQKKLAQVEE-- 55
DAI+ K + ++L++DN D Q + ++ K+N E +++ + AQ E
Sbjct: 2217 DAIQSKEEEIRLKEDNCSVLKDQLRQMS--IHMEELKINISRLEHDKQIWESKAQTEVQL 2274
Query: 56 -----DLILNKNK-----LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 105
D + +NK LE+ + +L E+E+ +L ++ + LEK +E+
Sbjct: 2275 QQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQ 2334
Query: 106 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 165
G + + QQ AD N K + + D + +LT++L E+ + K ++
Sbjct: 2335 KGNLEG--IIRQQEADIQN--SKFSYEQLETDLQASRELTSRLH------EEINMKEQKI 2384
Query: 166 SRKLAFVEDELEVAEDRVK-SGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXX 224
L+ E+ ++VA ++ D +I ELE L LE +KA + +
Sbjct: 2385 ISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMET 2444
Query: 225 XXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
K++ LQ + DR+ + ++R+ S+ E D E A
Sbjct: 2445 LKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAA 2502
Score = 52.0 bits (119), Expect = 2e-06
Identities = 42/197 (21%), Positives = 93/197 (47%), Gaps = 8/197 (4%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
+++++K A A++ +Q+ + L+ + E +RELQ KL ++++ + + +
Sbjct: 1352 EIESLKTVSHEAEVHAESLQQKLESSQLQIAGL-EHLRELQPKLDELQKLISKKEEDVSY 1410
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+ L EKE LT + E+ ++ Q+E ++ +ER Q +L E +Q +E
Sbjct: 1411 LSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEE 1470
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED---ADGKSDEVSRKLAFVEDELEVA 179
+ + ++ + + LKE + L E+ A G + +++ LA VE ++
Sbjct: 1471 IGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQ 1530
Query: 180 EDRVKSGDAKISELEEE 196
+ +++ L+EE
Sbjct: 1531 NKEKDTVLGRLALLQEE 1547
Score = 49.6 bits (113), Expect = 1e-05
Identities = 58/265 (21%), Positives = 116/265 (43%), Gaps = 21/265 (7%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKK--LAQVEEDLI 58
M +KK + ++ EK + + E + R L EK+ +E K +++E L
Sbjct: 1958 MKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYL--EKIQGAQKEPGNKSHAKELQELLK 2015
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
+ +++Q KD +++++A E V AL + ++DLE ++E A +E ++
Sbjct: 2016 EKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQA----VEHRK 2071
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
A KVL + Q + R+ L + LK + L + + ++ +K +E LE
Sbjct: 2072 KAQAELASFKVLLDDTQSEAARV--LADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQ 2129
Query: 179 AEDR----VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXX 234
AE++ K+ K+ L E + ++ ++V+ K ++ V++
Sbjct: 2130 AEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQL-------QENLDS 2182
Query: 235 XXXXXXXXXKTVKKLQKEVDRLEDE 259
K++ LQ + DR+ DE
Sbjct: 2183 TVTQLAAFTKSMSSLQDDRDRVIDE 2207
Score = 46.8 bits (106), Expect = 9e-05
Identities = 42/222 (18%), Positives = 111/222 (50%), Gaps = 16/222 (7%)
Query: 2 DAIKKKMQAMKLEKDNAMD-KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
D+ +K++ ++L+++ ++ K E++ +++ E+ NE++R L + ++DL
Sbjct: 2548 DSQQKQLLEVQLQQNKELENKYAKLEEKLKES----EEANEDLRRSFNALQEEKQDL--- 2600
Query: 61 KNKLEQANKDLEEKEKQLTATEAE--VAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
++E + + +Q+TA + E + + +++ EE++ + ++Q+++ E ++
Sbjct: 2601 SKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEE 2660
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
+C V + A++ E D+L +LK A +++ ++A + +L
Sbjct: 2661 EL-----VC-VQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVE 2714
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
E ++ + L +++ G S+ SL+ S + AN+ ++E
Sbjct: 2715 MEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDE 2756
Score = 44.4 bits (100), Expect = 5e-04
Identities = 51/220 (23%), Positives = 99/220 (45%), Gaps = 21/220 (9%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+ +++Q M+ E + + T E + ++ + EK+ EV E + ++E++ +
Sbjct: 292 LSQQLQQMEAEHNTLRN---TVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQ 348
Query: 64 LEQANKDLEEKEKQLTATEAE-VAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
EQA + E E + +A E + A + K I S +++G Q +A + D+
Sbjct: 349 FEQAGQAQAELESRYSALEQKHKAEMEEKTSHI-----LSLQKTGQELQSACDALK--DQ 401
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQL----KEARLLAEDADGKSDEVSRKLAFV----ED 174
N+++ + +A Q + + QL +QL KE + E + + +F E
Sbjct: 402 NSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEG 461
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
V E+ + S ++ ELE E + L S+E+ E KA
Sbjct: 462 TQAVTEENIASLQKRVVELENEKGAL--LLSSIELEELKA 499
Score = 43.6 bits (98), Expect = 8e-04
Identities = 40/218 (18%), Positives = 98/218 (44%), Gaps = 5/218 (2%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+ +++ ++ +E + K + + + D L+ + + +R LQ +L E +++ +
Sbjct: 794 LTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAER 853
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ + +EE + L+ E E+ +++ + + + D+E ++ Q++ E S E
Sbjct: 854 VRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTE- 912
Query: 124 NRMCKVLENRAQQDEE--RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
+M ++ E + E + + N L A ++ + +EVS L DE+ A
Sbjct: 913 -KMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQ 971
Query: 182 RVKSG-DAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
K + L++E + L++ ++ ++ QRV
Sbjct: 972 ISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRV 1009
Score = 40.3 bits (90), Expect = 0.007
Identities = 42/207 (20%), Positives = 94/207 (45%), Gaps = 16/207 (7%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVR--ELQKKLAQVEEDLILNKNKLEQANKDL 71
+KD + K + + +AE + +V + Q + A+V D + K +L Q+NK
Sbjct: 2053 QKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKEL-QSNK-- 2109
Query: 72 EEKEKQLTATEAEVAALNRKVQQIEE----DLEKSEERSGTAQQKLLEAQQSADENNRMC 127
E + Q+ + + L R+++Q EE + + +E+ +++ + +++ E
Sbjct: 2110 ESVKSQMKQKDED---LERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTL 2166
Query: 128 KVLENRAQQDEERMDQLTNQL----KEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
+ QQ +E +D QL K L +D D DE + D ++ E+ +
Sbjct: 2167 NKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEI 2226
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVS 210
+ + S L+++L+ + ++ L+++
Sbjct: 2227 RLKEDNCSVLKDQLRQMSIHMEELKIN 2253
Score = 38.7 bits (86), Expect = 0.023
Identities = 48/209 (22%), Positives = 99/209 (47%), Gaps = 23/209 (11%)
Query: 21 KADTCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQL 78
+A+ E + + ++ +E K +EEV +LQ+++ + ++ K +A E +++L
Sbjct: 1315 EAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKL 1374
Query: 79 TATEAEVAALNR------KVQQIEEDLEKSEE----RSGTAQQK---LLEAQQSADENNR 125
+++ ++A L K+ ++++ + K EE SG +K L + Q E
Sbjct: 1375 ESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQED 1434
Query: 126 MCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
+ K LE +A++ +ER+ QL +L E + E+ E SR ++ +L+ A
Sbjct: 1435 LIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEI----GEESRAKQQIQRKLQAALI 1490
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVS 210
K + L+EEL + +++ L S
Sbjct: 1491 SRKEALKENKSLQEELSLARGTIERLTKS 1519
Score = 38.7 bits (86), Expect = 0.023
Identities = 59/287 (20%), Positives = 124/287 (43%), Gaps = 29/287 (10%)
Query: 1 MDAIKKKMQAMK-LEKDNAMDKA--DTCEQQARDANLRAEKVNEEVRELQKKLAQV--EE 55
+D + M+ +K ++K+N KA D+ + +++ + ++L+++ + E+
Sbjct: 2435 VDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEK 2494
Query: 56 DLILNKNKLEQANKDLEEKEKQLTA----TEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 111
D ++ + E N L+E+ + L + +E A L+ ++ Q EDL + + Q+
Sbjct: 2495 DQLIQEAAAE--NNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQK 2552
Query: 112 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
+LLE Q + K LEN+ + EE+ LKE+ ED + + +
Sbjct: 2553 QLLEVQLQQN------KELENKYAKLEEK-------LKESEEANEDLRRSFNALQEEKQD 2599
Query: 172 VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXX 231
+ E+E + + +++ L+EE +G L+V EE+ ++ F
Sbjct: 2600 LSKEIESLKVSISQLTRQVTALQEE-GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAEL 2658
Query: 232 XXXXXXXXXXXXKTV----KKLQKEVDRLEDELGINKDRYKSLADEM 274
K V KL+KE+ L + GI ++ ++ + +
Sbjct: 2659 EEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERV 2705
Score = 38.3 bits (85), Expect = 0.030
Identities = 48/222 (21%), Positives = 95/222 (42%), Gaps = 14/222 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLR--AEKVNEEVRELQKKLAQVEEDLI 58
+D +K+K A K+ A K + RDA L A +N L ++ + L+
Sbjct: 2754 LDELKRKYDASL--KELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLL 2811
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
+L + LE+ Q+ + +A+L + + +LEK + Q+ +
Sbjct: 2812 SKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPST 2871
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
S E + K + + Q D +R+ LKE + L + + E++ +L ++ +L+
Sbjct: 2872 SPAEVQSLKKAMSS-LQNDRDRL------LKELKNLQQQYLQINQEIT-ELHPLKAQLQE 2923
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+D+ K+ EL +E + L L + EK++ + E
Sbjct: 2924 YQDKTKAFQIMQEELRQENLSWQHELHQLRM--EKSSWEIHE 2963
Score = 37.9 bits (84), Expect = 0.040
Identities = 39/165 (23%), Positives = 79/165 (47%), Gaps = 15/165 (9%)
Query: 3 AIKKKMQAMKLEKDNAMD--KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
A+ K+M +K N +D +A+ E QA L + + +A V+E ++++
Sbjct: 1092 ALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGD---SVALVKETVVIS 1148
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI----EEDLEKSEERSGTAQQKLLEA 116
+ E E+++ A E E L +K+Q+ + L+K++E+ +++L
Sbjct: 1149 PPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREEL--- 1205
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
+Q D+ NR+ + + +++++E DQL + R E DGK
Sbjct: 1206 KQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVR---ESIDGK 1247
Score = 37.5 bits (83), Expect = 0.053
Identities = 35/234 (14%), Positives = 115/234 (49%), Gaps = 23/234 (9%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ +++++K + + + + C++Q + + +++ + Q+E DL ++
Sbjct: 2310 LESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASREL 2369
Query: 64 LEQANKDLEEKEKQL--------TATEAEVAAL----NRKVQQIEEDLEKSEERSGTAQQ 111
+ ++++ KE+++ A + +A L +++++++E L + EE + ++
Sbjct: 2370 TSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEE 2429
Query: 112 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD---GKSDEV-SR 167
E +++ D+ N++ + L+ +++ ++ QL + +K L D D G ++ R
Sbjct: 2430 ---ENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEER 2486
Query: 168 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
L+ + ++ + ++ A+ ++L+EE++ + + + L K + + ++
Sbjct: 2487 HLSIILEK----DQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQY 2536
Score = 36.7 bits (81), Expect = 0.092
Identities = 57/265 (21%), Positives = 117/265 (44%), Gaps = 36/265 (13%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDL--ILNKNKLEQANKDLE--EKEKQLTAT 81
E + R L+A +N +EL ++++++EE+L + +++K E + E E E+
Sbjct: 987 ENEQRKRKLQAALINR--KELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENK 1044
Query: 82 EAEVAALNRKVQQIEEDLEKS-EERSGTAQ--QKLLEAQQSADEN-NRMCKVLENRAQQD 137
E + K Q+IE L+++ E+ Q +K LE + +A+E + K + Q
Sbjct: 1045 EYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDK 1104
Query: 138 EERMDQLTNQLKEARLLAEDADGKSDEVSR--KLAFVEDELEVAEDRVKSGDAKISELEE 195
++D L ++ E + + + + + S +A V++ + ++ S + ELEE
Sbjct: 1105 TNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEE 1164
Query: 196 ELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDR 255
++ +LE +E+ ++++E +KK Q++
Sbjct: 1165 KIL-------ALEKEKEQLQKKLQE-----------------ALTSRKAILKKAQEKERH 1200
Query: 256 LEDELGINKDRYKSLADEMDSTFAE 280
L +EL KD Y L ++ D E
Sbjct: 1201 LREELKQQKDDYNRLQEQFDEQSKE 1225
Score = 35.9 bits (79), Expect = 0.16
Identities = 39/186 (20%), Positives = 81/186 (43%), Gaps = 11/186 (5%)
Query: 41 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALN----RKVQQIE 96
E++ + K + E ++ K+KL++ + + + QLT +AE A + + ++
Sbjct: 130 EQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMK 189
Query: 97 EDLEKSEERSGTAQQKL--LEAQQSADENNRMCKV-LENRAQQDEERMDQLTNQLKEARL 153
+ L++ EE T Q +L +A+Q+A + R E + + E+ + QL Q
Sbjct: 190 QQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQAD---- 245
Query: 154 LAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
+ + K + RKL E+ L V +++ E+ +++ L+ +E
Sbjct: 246 VETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNT 305
Query: 214 ANQRVE 219
VE
Sbjct: 306 LRNTVE 311
Score = 35.5 bits (78), Expect = 0.21
Identities = 20/93 (21%), Positives = 50/93 (53%), Gaps = 3/93 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++K++Q ++ N +D A Q+ + +++ EE+RE Q+ ++ ++ L + +
Sbjct: 3093 LEKQVQELQAGPLN-IDVAPGAPQEKNGVHRKSDP--EELREPQQSFSEAQQQLCNTRQE 3149
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+ + K LEE+ Q A E ++ +++++E
Sbjct: 3150 VNELRKLLEEERDQRVAAENALSVAEEQIRRLE 3182
Score = 34.7 bits (76), Expect = 0.37
Identities = 45/235 (19%), Positives = 106/235 (45%), Gaps = 24/235 (10%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQ---------ARDANLRAEKVNEEVRELQKKLA 51
+D +K+++ ++ EK + + T E + +D L+ + EEV ++
Sbjct: 1842 IDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKM--LQEEVTKMNLLNQ 1899
Query: 52 QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 111
Q++E+L E A ++ ++ E++L ++A LN + +D+ ++ ++ +
Sbjct: 1900 QIQEELSRVTKLKETAEEEKDDLEERLM---NQLAELNGSIGNYCQDVTDAQIKNELLES 1956
Query: 112 KLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS--DEVSRK 168
++ ++ E ++++ + + + E + +++ A+ ++ KS E+
Sbjct: 1957 EMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQ---KEPGNKSHAKELQEL 2013
Query: 169 LAFVEDELEVAEDRVKSGDAKISELEEELK----VVGNSLKSLEVSEEKANQRVE 219
L + E++ + KIS LE +K V S K LE+++E Q VE
Sbjct: 2014 LKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVE 2068
Score = 34.3 bits (75), Expect = 0.49
Identities = 49/252 (19%), Positives = 108/252 (42%), Gaps = 19/252 (7%)
Query: 41 EEVRELQKKLAQVEEDLILNK-------NKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 93
+++ +L++++A +EE+ NK N+ + K+ +L + EV +N Q
Sbjct: 1840 QQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQ 1899
Query: 94 QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD-QLTNQLKEAR 152
QI+E+L + + TA+++ + ++ N++ ++ + ++ D Q+ N+L E+
Sbjct: 1900 QIQEELSRVTKLKETAEEEKDDLEERL--MNQLAELNGSIGNYCQDVTDAQIKNELLESE 1957
Query: 153 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
+ S+ K V+++ +V + K KI ++E ++ + E+ +E
Sbjct: 1958 -MKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKE 2016
Query: 213 KANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLAD 272
K Q V++ +TVK L+ + +L I K+ +
Sbjct: 2017 K-QQEVKQL-------QKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVE 2068
Query: 273 EMDSTFAELAGY 284
AELA +
Sbjct: 2069 HRKKAQAELASF 2080
Score = 33.9 bits (74), Expect = 0.65
Identities = 42/227 (18%), Positives = 102/227 (44%), Gaps = 11/227 (4%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTC--EQQARDANLRAEKVN-EEVRELQKKLAQVEEDLI 58
D + ++ ++ E+D + + D E Q+ ++ + K+ E + E ++KL V+E
Sbjct: 1535 DTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKL--VKEIES 1592
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
L +K+ ++ + +EK K+L + V E ++ E +Q+L +
Sbjct: 1593 LKSSKIAEST-EWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLR 1651
Query: 119 SADENNRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
S + N + K L+ Q+ EE +++ K + + + ++D + ++ D +
Sbjct: 1652 STEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAK 1711
Query: 178 VAEDRVKSGDAKISELEEELKV----VGNSLKSLEVSEEKANQRVEE 220
+ + S +A + E E +K+ + +SL ++ ++ V++
Sbjct: 1712 ECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQD 1758
Score = 33.9 bits (74), Expect = 0.65
Identities = 53/240 (22%), Positives = 107/240 (44%), Gaps = 25/240 (10%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQ----ARDANLRAEKVNEEVRELQKKLAQVEE-- 55
D +KK+++ + + ++ +T E++ ARD +K+ +E + AQ++
Sbjct: 2678 DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFG 2737
Query: 56 -DLILNKNKLEQANKDLEEKEKQLTATEAEVA------ALNRK----VQQIEEDLEKSEE 104
+ +N + AN++L+E +++ A+ E+A LNR+ + + + +EE
Sbjct: 2738 RSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEE 2797
Query: 105 RSGTAQQKLLEAQQSADEN-NRMCKVLE---NRAQQDEERMDQLTNQLKEARLLAEDADG 160
S + +KL + S DE + LE N+ Q + M L N+ L E
Sbjct: 2798 NSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNE--RDHLWNELEKF 2855
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ E ++ + + AE V+S +S L+ + + LK+L+ + NQ + E
Sbjct: 2856 RKSEEGKQRSAAQPSTSPAE--VQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITE 2913
Score = 32.3 bits (70), Expect = 2.0
Identities = 45/209 (21%), Positives = 96/209 (45%), Gaps = 21/209 (10%)
Query: 23 DTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATE 82
D Q A++ E + +++R LQ+KL + EE L+ + DL ++E LTA E
Sbjct: 235 DELLQLVTQADVETE-MQQKLRVLQRKLEEHEESLVGRAQVV-----DLLQQE--LTAAE 286
Query: 83 AEVAALNRKVQQIEED-------LEKSEERSGTAQQKL-LEAQQSADENNRMCKVLENRA 134
L++++QQ+E + +E E S +K+ LE + + + + + +
Sbjct: 287 QRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLL 346
Query: 135 QQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE---DELEVAEDRVKSGDAKIS 191
+Q E+ L + + +E + + ++ EL+ A D +K ++K+
Sbjct: 347 EQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLL 406
Query: 192 ELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ + E V S ++++ E++ Q+ +E
Sbjct: 407 QDKNEQAV--QSAQTIQQLEDQLQQKSKE 433
Score = 31.9 bits (69), Expect = 2.6
Identities = 39/188 (20%), Positives = 82/188 (43%), Gaps = 20/188 (10%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE------DLILN 60
K+Q + D + + L ++N+ ++E+ +K ++++ L+
Sbjct: 3002 KVQYQRQASPETSASPDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLEE 3061
Query: 61 KNKLE----QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
KN L ++ L E ++ A L ++VQ+++ + G Q+K
Sbjct: 3062 KNTLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQELQAGPLNIDVAPGAPQEKNGVH 3121
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
++S E R + + AQQ Q N+L+ +LL E+ D +++A E+ L
Sbjct: 3122 RKSDPEELREPQQSFSEAQQQLCNTRQEVNELR--KLLEEERD-------QRVA-AENAL 3171
Query: 177 EVAEDRVK 184
VAE++++
Sbjct: 3172 SVAEEQIR 3179
>D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 protein.
Length = 3225
Score = 56.8 bits (131), Expect = 8e-08
Identities = 50/234 (21%), Positives = 119/234 (50%), Gaps = 20/234 (8%)
Query: 4 IKKKMQAMKLE-KDNAMDKADTCE---QQARDANLRAEK-VNEEVRELQKKLAQVEEDLI 58
+KK++Q+ K K K + E +QA + +L+ +K + E++ L+++ +EE +
Sbjct: 2067 LKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIG 2126
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
+ L + +K++++ ++ L +T ++AA + + +++D ++ + + ++K +A Q
Sbjct: 2127 EIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQ 2186
Query: 119 SADENNRM----CKVLENRAQQDEERMDQLT---NQLKEARLLAEDADGKSDEVSRKLAF 171
S +E R+ C VL+++ +Q M++L ++L+ + + E ++ +K+
Sbjct: 2187 SKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCD 2246
Query: 172 --------VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQR 217
+ +LE S ++++LE ELK + + L L S EK ++
Sbjct: 2247 TLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQ 2300
Score = 54.8 bits (126), Expect = 3e-07
Identities = 66/298 (22%), Positives = 124/298 (41%), Gaps = 29/298 (9%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN----EEVRELQKKLAQVEE-- 55
DAI+ K + ++L++DN D Q + ++ K+N E +++ + AQ E
Sbjct: 2183 DAIQSKEEEIRLKEDNCSVLKDQLRQMS--IHMEELKINISRLEHDKQIWESKAQTEVQL 2240
Query: 56 -----DLILNKNK-----LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 105
D + +NK LE+ + +L E+E+ +L ++ + LEK +E+
Sbjct: 2241 QQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQ 2300
Query: 106 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 165
G + + QQ AD N K + + D + +LT++L E+ + K ++
Sbjct: 2301 KGNLEG--IIRQQEADIQN--SKFSYEQLETDLQASRELTSRLH------EEINMKEQKI 2350
Query: 166 SRKLAFVEDELEVAEDRVK-SGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXX 224
L+ E+ ++VA ++ D +I ELE L LE +KA + +
Sbjct: 2351 ISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMET 2410
Query: 225 XXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
K++ LQ + DR+ + ++R+ S+ E D E A
Sbjct: 2411 LKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAA 2468
Score = 52.0 bits (119), Expect = 2e-06
Identities = 42/197 (21%), Positives = 93/197 (47%), Gaps = 8/197 (4%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
+++++K A A++ +Q+ + L+ + E +RELQ KL ++++ + + +
Sbjct: 1318 EIESLKTVSHEAEVHAESLQQKLESSQLQIAGL-EHLRELQPKLDELQKLISKKEEDVSY 1376
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+ L EKE LT + E+ ++ Q+E ++ +ER Q +L E +Q +E
Sbjct: 1377 LSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEE 1436
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED---ADGKSDEVSRKLAFVEDELEVA 179
+ + ++ + + LKE + L E+ A G + +++ LA VE ++
Sbjct: 1437 IGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQ 1496
Query: 180 EDRVKSGDAKISELEEE 196
+ +++ L+EE
Sbjct: 1497 NKEKDTVLGRLALLQEE 1513
Score = 49.6 bits (113), Expect = 1e-05
Identities = 58/265 (21%), Positives = 116/265 (43%), Gaps = 21/265 (7%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKK--LAQVEEDLI 58
M +KK + ++ EK + + E + R L EK+ +E K +++E L
Sbjct: 1924 MKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYL--EKIQGAQKEPGNKSHAKELQELLK 1981
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
+ +++Q KD +++++A E V AL + ++DLE ++E A +E ++
Sbjct: 1982 EKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQA----VEHRK 2037
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
A KVL + Q + R+ L + LK + L + + ++ +K +E LE
Sbjct: 2038 KAQAELASFKVLLDDTQSEAARV--LADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQ 2095
Query: 179 AEDR----VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXX 234
AE++ K+ K+ L E + ++ ++V+ K ++ V++
Sbjct: 2096 AEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQL-------QENLDS 2148
Query: 235 XXXXXXXXXKTVKKLQKEVDRLEDE 259
K++ LQ + DR+ DE
Sbjct: 2149 TVTQLAAFTKSMSSLQDDRDRVIDE 2173
Score = 47.2 bits (107), Expect = 7e-05
Identities = 44/202 (21%), Positives = 100/202 (49%), Gaps = 8/202 (3%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E++ + L+A+ + + + ++EE ++ K +L++ + + + QL+ T+AE
Sbjct: 116 EKEELISTLQAQLTQAQAEQPAQSSTEMEE-FVMMKQQLQEKEEFISTLQAQLSQTQAEQ 174
Query: 86 AALNRKVQQIEEDLE-KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQL 144
AA +QQ+ + + + E + + +LL+ AD M + L ++ EE + L
Sbjct: 175 AAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESL 234
Query: 145 TNQLKEARLLAED---ADGKSDEVSRKLAFVEDELEVAEDRVKS--GDAKISELEEELKV 199
+ + LL ++ A+ ++ +S++L +E E + V++ ++KI + EL+V
Sbjct: 235 VGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEV 294
Query: 200 VGNSLKSLEVSEEKANQRVEEF 221
L S +E+ + +E+F
Sbjct: 295 AERKL-SFHNLQEEMHHLLEQF 315
Score = 46.8 bits (106), Expect = 9e-05
Identities = 42/222 (18%), Positives = 111/222 (50%), Gaps = 16/222 (7%)
Query: 2 DAIKKKMQAMKLEKDNAMD-KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
D+ +K++ ++L+++ ++ K E++ +++ E+ NE++R L + ++DL
Sbjct: 2514 DSQQKQLLEVQLQQNKELENKYAKLEEKLKES----EEANEDLRRSFNALQEEKQDL--- 2566
Query: 61 KNKLEQANKDLEEKEKQLTATEAE--VAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
++E + + +Q+TA + E + + +++ EE++ + ++Q+++ E ++
Sbjct: 2567 SKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEE 2626
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
+C V + A++ E D+L +LK A +++ ++A + +L
Sbjct: 2627 EL-----VC-VQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVE 2680
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
E ++ + L +++ G S+ SL+ S + AN+ ++E
Sbjct: 2681 MEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDE 2722
Score = 44.4 bits (100), Expect = 5e-04
Identities = 51/220 (23%), Positives = 99/220 (45%), Gaps = 21/220 (9%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+ +++Q M+ E + + T E + ++ + EK+ EV E + ++E++ +
Sbjct: 258 LSQQLQQMEAEHNTLRN---TVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQ 314
Query: 64 LEQANKDLEEKEKQLTATEAE-VAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
EQA + E E + +A E + A + K I S +++G Q +A + D+
Sbjct: 315 FEQAGQAQAELESRYSALEQKHKAEMEEKTSHI-----LSLQKTGQELQSACDALK--DQ 367
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQL----KEARLLAEDADGKSDEVSRKLAFV----ED 174
N+++ + +A Q + + QL +QL KE + E + + +F E
Sbjct: 368 NSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEG 427
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
V E+ + S ++ ELE E + L S+E+ E KA
Sbjct: 428 TQAVTEENIASLQKRVVELENEKGAL--LLSSIELEELKA 465
Score = 43.6 bits (98), Expect = 8e-04
Identities = 40/218 (18%), Positives = 98/218 (44%), Gaps = 5/218 (2%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+ +++ ++ +E + K + + + D L+ + + +R LQ +L E +++ +
Sbjct: 760 LTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAER 819
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+ + +EE + L+ E E+ +++ + + + D+E ++ Q++ E S E
Sbjct: 820 VRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTE- 878
Query: 124 NRMCKVLENRAQQDEE--RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
+M ++ E + E + + N L A ++ + +EVS L DE+ A
Sbjct: 879 -KMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQ 937
Query: 182 RVKSG-DAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
K + L++E + L++ ++ ++ QRV
Sbjct: 938 ISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRV 975
Score = 40.3 bits (90), Expect = 0.007
Identities = 42/207 (20%), Positives = 94/207 (45%), Gaps = 16/207 (7%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVR--ELQKKLAQVEEDLILNKNKLEQANKDL 71
+KD + K + + +AE + +V + Q + A+V D + K +L Q+NK
Sbjct: 2019 QKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKEL-QSNK-- 2075
Query: 72 EEKEKQLTATEAEVAALNRKVQQIEE----DLEKSEERSGTAQQKLLEAQQSADENNRMC 127
E + Q+ + + L R+++Q EE + + +E+ +++ + +++ E
Sbjct: 2076 ESVKSQMKQKDED---LERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTL 2132
Query: 128 KVLENRAQQDEERMDQLTNQL----KEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
+ QQ +E +D QL K L +D D DE + D ++ E+ +
Sbjct: 2133 NKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEI 2192
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVS 210
+ + S L+++L+ + ++ L+++
Sbjct: 2193 RLKEDNCSVLKDQLRQMSIHMEELKIN 2219
Score = 38.7 bits (86), Expect = 0.023
Identities = 48/209 (22%), Positives = 99/209 (47%), Gaps = 23/209 (11%)
Query: 21 KADTCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQL 78
+A+ E + + ++ +E K +EEV +LQ+++ + ++ K +A E +++L
Sbjct: 1281 EAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKL 1340
Query: 79 TATEAEVAALNR------KVQQIEEDLEKSEE----RSGTAQQK---LLEAQQSADENNR 125
+++ ++A L K+ ++++ + K EE SG +K L + Q E
Sbjct: 1341 ESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQED 1400
Query: 126 MCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
+ K LE +A++ +ER+ QL +L E + E+ E SR ++ +L+ A
Sbjct: 1401 LIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEI----GEESRAKQQIQRKLQAALI 1456
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVS 210
K + L+EEL + +++ L S
Sbjct: 1457 SRKEALKENKSLQEELSLARGTIERLTKS 1485
Score = 38.7 bits (86), Expect = 0.023
Identities = 59/287 (20%), Positives = 124/287 (43%), Gaps = 29/287 (10%)
Query: 1 MDAIKKKMQAMK-LEKDNAMDKA--DTCEQQARDANLRAEKVNEEVRELQKKLAQV--EE 55
+D + M+ +K ++K+N KA D+ + +++ + ++L+++ + E+
Sbjct: 2401 VDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEK 2460
Query: 56 DLILNKNKLEQANKDLEEKEKQLTA----TEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 111
D ++ + E N L+E+ + L + +E A L+ ++ Q EDL + + Q+
Sbjct: 2461 DQLIQEAAAE--NNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQK 2518
Query: 112 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
+LLE Q + K LEN+ + EE+ LKE+ ED + + +
Sbjct: 2519 QLLEVQLQQN------KELENKYAKLEEK-------LKESEEANEDLRRSFNALQEEKQD 2565
Query: 172 VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXX 231
+ E+E + + +++ L+EE +G L+V EE+ ++ F
Sbjct: 2566 LSKEIESLKVSISQLTRQVTALQEE-GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAEL 2624
Query: 232 XXXXXXXXXXXXKTV----KKLQKEVDRLEDELGINKDRYKSLADEM 274
K V KL+KE+ L + GI ++ ++ + +
Sbjct: 2625 EEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERV 2671
Score = 38.3 bits (85), Expect = 0.030
Identities = 35/161 (21%), Positives = 78/161 (48%), Gaps = 7/161 (4%)
Query: 41 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALN----RKVQQIE 96
E++ + K + E ++ K+KL++ + + + QLT +AE A + + ++
Sbjct: 91 EQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMK 150
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
+ L++ EE T Q +L +Q A++ ++ + + ++D Q+ E L
Sbjct: 151 QQLQEKEEFISTLQAQL--SQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVT 208
Query: 157 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 197
AD ++ E+ +KL ++ +LE E+ + + L++EL
Sbjct: 209 QADVET-EMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQEL 248
Score = 38.3 bits (85), Expect = 0.030
Identities = 48/222 (21%), Positives = 95/222 (42%), Gaps = 14/222 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLR--AEKVNEEVRELQKKLAQVEEDLI 58
+D +K+K A K+ A K + RDA L A +N L ++ + L+
Sbjct: 2720 LDELKRKYDASL--KELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLL 2777
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
+L + LE+ Q+ + +A+L + + +LEK + Q+ +
Sbjct: 2778 SKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPST 2837
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
S E + K + + Q D +R+ LKE + L + + E++ +L ++ +L+
Sbjct: 2838 SPAEVQSLKKAMSS-LQNDRDRL------LKELKNLQQQYLQINQEIT-ELHPLKAQLQE 2889
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+D+ K+ EL +E + L L + EK++ + E
Sbjct: 2890 YQDKTKAFQIMQEELRQENLSWQHELDQLRM--EKSSWEIHE 2929
Score = 37.9 bits (84), Expect = 0.040
Identities = 39/165 (23%), Positives = 79/165 (47%), Gaps = 15/165 (9%)
Query: 3 AIKKKMQAMKLEKDNAMD--KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
A+ K+M +K N +D +A+ E QA L + + +A V+E ++++
Sbjct: 1058 ALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGD---SVALVKETVVIS 1114
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI----EEDLEKSEERSGTAQQKLLEA 116
+ E E+++ A E E L +K+Q+ + L+K++E+ +++L
Sbjct: 1115 PPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREEL--- 1171
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 161
+Q D+ NR+ + + +++++E DQL + R E DGK
Sbjct: 1172 KQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVR---ESIDGK 1213
Score = 37.5 bits (83), Expect = 0.053
Identities = 35/234 (14%), Positives = 115/234 (49%), Gaps = 23/234 (9%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ +++++K + + + + C++Q + + +++ + Q+E DL ++
Sbjct: 2276 LESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASREL 2335
Query: 64 LEQANKDLEEKEKQL--------TATEAEVAAL----NRKVQQIEEDLEKSEERSGTAQQ 111
+ ++++ KE+++ A + +A L +++++++E L + EE + ++
Sbjct: 2336 TSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEE 2395
Query: 112 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD---GKSDEV-SR 167
E +++ D+ N++ + L+ +++ ++ QL + +K L D D G ++ R
Sbjct: 2396 ---ENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEER 2452
Query: 168 KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
L+ + ++ + ++ A+ ++L+EE++ + + + L K + + ++
Sbjct: 2453 HLSIILEK----DQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQY 2502
Score = 36.7 bits (81), Expect = 0.092
Identities = 57/265 (21%), Positives = 117/265 (44%), Gaps = 36/265 (13%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDL--ILNKNKLEQANKDLE--EKEKQLTAT 81
E + R L+A +N +EL ++++++EE+L + +++K E + E E E+
Sbjct: 953 ENEQRKRKLQAALINR--KELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENK 1010
Query: 82 EAEVAALNRKVQQIEEDLEKS-EERSGTAQ--QKLLEAQQSADEN-NRMCKVLENRAQQD 137
E + K Q+IE L+++ E+ Q +K LE + +A+E + K + Q
Sbjct: 1011 EYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDK 1070
Query: 138 EERMDQLTNQLKEARLLAEDADGKSDEVSR--KLAFVEDELEVAEDRVKSGDAKISELEE 195
++D L ++ E + + + + + S +A V++ + ++ S + ELEE
Sbjct: 1071 TNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEE 1130
Query: 196 ELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDR 255
++ +LE +E+ ++++E +KK Q++
Sbjct: 1131 KIL-------ALEKEKEQLQKKLQE-----------------ALTSRKAILKKAQEKERH 1166
Query: 256 LEDELGINKDRYKSLADEMDSTFAE 280
L +EL KD Y L ++ D E
Sbjct: 1167 LREELKQQKDDYNRLQEQFDEQSKE 1191
Score = 35.5 bits (78), Expect = 0.21
Identities = 20/93 (21%), Positives = 50/93 (53%), Gaps = 3/93 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++K++Q ++ N +D A Q+ + +++ EE+RE Q+ ++ ++ L + +
Sbjct: 3059 LEKQVQELQAGPLN-IDVAPGAPQEKNGVHRKSDP--EELREPQQSFSEAQQQLCNTRQE 3115
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+ + K LEE+ Q A E ++ +++++E
Sbjct: 3116 VNELRKLLEEERDQRVAAENALSVAEEQIRRLE 3148
Score = 34.7 bits (76), Expect = 0.37
Identities = 45/235 (19%), Positives = 106/235 (45%), Gaps = 24/235 (10%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQ---------ARDANLRAEKVNEEVRELQKKLA 51
+D +K+++ ++ EK + + T E + +D L+ + EEV ++
Sbjct: 1808 IDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKM--LQEEVTKMNLLNQ 1865
Query: 52 QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 111
Q++E+L E A ++ ++ E++L ++A LN + +D+ ++ ++ +
Sbjct: 1866 QIQEELSRVTKLKETAEEEKDDLEERLM---NQLAELNGSIGNYCQDVTDAQIKNELLES 1922
Query: 112 KLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS--DEVSRK 168
++ ++ E ++++ + + + E + +++ A+ ++ KS E+
Sbjct: 1923 EMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQ---KEPGNKSHAKELQEL 1979
Query: 169 LAFVEDELEVAEDRVKSGDAKISELEEELK----VVGNSLKSLEVSEEKANQRVE 219
L + E++ + KIS LE +K V S K LE+++E Q VE
Sbjct: 1980 LKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVE 2034
Score = 34.3 bits (75), Expect = 0.49
Identities = 49/252 (19%), Positives = 108/252 (42%), Gaps = 19/252 (7%)
Query: 41 EEVRELQKKLAQVEEDLILNK-------NKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 93
+++ +L++++A +EE+ NK N+ + K+ +L + EV +N Q
Sbjct: 1806 QQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQ 1865
Query: 94 QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD-QLTNQLKEAR 152
QI+E+L + + TA+++ + ++ N++ ++ + ++ D Q+ N+L E+
Sbjct: 1866 QIQEELSRVTKLKETAEEEKDDLEERL--MNQLAELNGSIGNYCQDVTDAQIKNELLESE 1923
Query: 153 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
+ S+ K V+++ +V + K KI ++E ++ + E+ +E
Sbjct: 1924 -MKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKE 1982
Query: 213 KANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLAD 272
K Q V++ +TVK L+ + +L I K+ +
Sbjct: 1983 K-QQEVKQL-------QKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVE 2034
Query: 273 EMDSTFAELAGY 284
AELA +
Sbjct: 2035 HRKKAQAELASF 2046
Score = 33.9 bits (74), Expect = 0.65
Identities = 42/227 (18%), Positives = 102/227 (44%), Gaps = 11/227 (4%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTC--EQQARDANLRAEKVN-EEVRELQKKLAQVEEDLI 58
D + ++ ++ E+D + + D E Q+ ++ + K+ E + E ++KL V+E
Sbjct: 1501 DTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKL--VKEIES 1558
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
L +K+ ++ + +EK K+L + V E ++ E +Q+L +
Sbjct: 1559 LKSSKIAEST-EWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLR 1617
Query: 119 SADENNRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
S + N + K L+ Q+ EE +++ K + + + ++D + ++ D +
Sbjct: 1618 STEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAK 1677
Query: 178 VAEDRVKSGDAKISELEEELKV----VGNSLKSLEVSEEKANQRVEE 220
+ + S +A + E E +K+ + +SL ++ ++ V++
Sbjct: 1678 ECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQD 1724
Score = 33.9 bits (74), Expect = 0.65
Identities = 53/240 (22%), Positives = 107/240 (44%), Gaps = 25/240 (10%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQ----ARDANLRAEKVNEEVRELQKKLAQVEE-- 55
D +KK+++ + + ++ +T E++ ARD +K+ +E + AQ++
Sbjct: 2644 DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFG 2703
Query: 56 -DLILNKNKLEQANKDLEEKEKQLTATEAEVA------ALNRK----VQQIEEDLEKSEE 104
+ +N + AN++L+E +++ A+ E+A LNR+ + + + +EE
Sbjct: 2704 RSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEE 2763
Query: 105 RSGTAQQKLLEAQQSADEN-NRMCKVLE---NRAQQDEERMDQLTNQLKEARLLAEDADG 160
S + +KL + S DE + LE N+ Q + M L N+ L E
Sbjct: 2764 NSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNE--RDHLWNELEKF 2821
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ E ++ + + AE V+S +S L+ + + LK+L+ + NQ + E
Sbjct: 2822 RKSEEGKQRSAAQPSTSPAE--VQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITE 2879
Score = 31.9 bits (69), Expect = 2.6
Identities = 39/188 (20%), Positives = 82/188 (43%), Gaps = 20/188 (10%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE------DLILN 60
K+Q + D + + L ++N+ ++E+ +K ++++ L+
Sbjct: 2968 KVQYQRQASPETSASPDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLEE 3027
Query: 61 KNKLE----QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
KN L ++ L E ++ A L ++VQ+++ + G Q+K
Sbjct: 3028 KNTLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQELQAGPLNIDVAPGAPQEKNGVH 3087
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
++S E R + + AQQ Q N+L+ +LL E+ D +++A E+ L
Sbjct: 3088 RKSDPEELREPQQSFSEAQQQLCNTRQEVNELR--KLLEEERD-------QRVA-AENAL 3137
Query: 177 EVAEDRVK 184
VAE++++
Sbjct: 3138 SVAEEQIR 3145
>AF200415-1|AAF08305.2| 1825|Homo sapiens proliferation-related
protein P80 protein.
Length = 1825
Score = 56.8 bits (131), Expect = 8e-08
Identities = 56/200 (28%), Positives = 98/200 (49%), Gaps = 11/200 (5%)
Query: 13 LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 72
LE ++ DT Q +D L + NE V++ K L Q DL LEQ +K LE
Sbjct: 1374 LEHKEVVEPKDTAIYQ-KDEALHVK--NEAVKQQDKALEQKGRDLEQKDTALEQKDKALE 1430
Query: 73 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN-NRMCKVLE 131
K+K L E + AL +K +I E+ +K+ E+ TA ++ +A + D++ + +VLE
Sbjct: 1431 PKDKDL---EEKDKALEQK-DKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLE 1486
Query: 132 NRAQQDEERMDQLTNQLKEARLLA-ED--ADGKSDEVSRKLAFVEDELEVAEDRVKSGDA 188
+ + EE+ L +++ A ED A+ K ++ + E + + E + K +
Sbjct: 1487 QKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEK 1546
Query: 189 KISELEEELKVVGNSLKSLE 208
K LE++ +G ++LE
Sbjct: 1547 KDQALEQKYWALGQKDEALE 1566
Score = 52.0 bits (119), Expect = 2e-06
Identities = 46/221 (20%), Positives = 107/221 (48%), Gaps = 5/221 (2%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE-DLIL-N 60
AI +K +A+ ++ + + EQ+ RD + + ++ + L+ K +EE D L
Sbjct: 1386 AIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQ 1445
Query: 61 KNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
K+K+ E+ +K LE+K+ L + + ++ ++Q + LE+ +E+ + K L+ +
Sbjct: 1446 KDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQ-KEKIPEEKDKALDQKVR 1504
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE-VSRKLAFVEDELEV 178
+ E+ + +D E+ D+ Q +A+ + K D+ + +K + + E
Sbjct: 1505 SVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEA 1564
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
E +++ + E+E V + + ++ EEK+ ++V+
Sbjct: 1565 LEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVK 1605
Score = 39.9 bits (89), Expect = 0.010
Identities = 35/156 (22%), Positives = 80/156 (51%), Gaps = 8/156 (5%)
Query: 47 QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE---KSE 103
QKK + +++++ K+K + + +E K+ + + + N V+Q ++ LE +
Sbjct: 1356 QKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDL 1415
Query: 104 ERSGTAQQKLLEAQQSADEN-NRMCKVLENRAQQDEERMDQLTNQLKEARLLAED--ADG 160
E+ TA ++ +A + D++ K LE + + EE+ D+ Q K+ L +D +
Sbjct: 1416 EQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEK-DKALEQ-KDTALEQKDKALEP 1473
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 196
K ++ +K +E + ++ E++ K+ D K+ +E +
Sbjct: 1474 KDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHK 1509
>BC046212-1|AAH46212.1| 364|Homo sapiens Similar to cytomatrix
protein p110 protein.
Length = 364
Score = 56.4 bits (130), Expect = 1e-07
Identities = 65/291 (22%), Positives = 124/291 (42%), Gaps = 21/291 (7%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQVEEDLILNKN 62
+K ++++++ + N T E+ + E++ E+ R+ +++L ++E NK+
Sbjct: 36 LKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKD 95
Query: 63 KLEQANK---DLEEKEKQLT-----ATEAEVAALNR--KVQQIEEDLE-KSEERSGTAQQ 111
E+ N +L EKE L A+ A L R K++ +E +E K EE S Q
Sbjct: 96 LKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQ 155
Query: 112 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
+A+Q ++ +E+ ++ + E DQ+ KEA ++ EV R L
Sbjct: 156 LKKQAEQLFNQMYNPAHNIEDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEVDRLLEI 215
Query: 172 VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXX 231
+++ E+ D KI+ELE +K ++ +V+ K NQ++E+
Sbjct: 216 LKE----VENEKNDKDKKIAELERHMKD-----QNKKVANLKHNQQLEKKKNAQLLEEVR 266
Query: 232 XXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELA 282
+++L +++ EL K R S + A LA
Sbjct: 267 RREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLA 317
Score = 48.0 bits (109), Expect = 4e-05
Identities = 48/218 (22%), Positives = 92/218 (42%), Gaps = 20/218 (9%)
Query: 48 KKLAQVEEDLI-LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS 106
K + +V+E I + + K+E + L +K+KQLT L +V+ ++ D ++
Sbjct: 2 KDMLEVKERKINVLQKKIENLQEQLRDKDKQLT-------NLKDRVKSLQTDSSNTDTAL 54
Query: 107 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 166
T ++ L E ++ + ++ E R + D ER++++ + KE + L E + E++
Sbjct: 55 ATLEEALSEKERIIE------RLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELT 108
Query: 167 RKLAFVEDELEVAEDRVKSG---DAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXX 223
K + + D E A +G D+K+ LE ++ LE +K + E+
Sbjct: 109 EKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKK---QAEQLFN 165
Query: 224 XXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELG 261
+K+L KE DE G
Sbjct: 166 QMYNPAHNIEDDSRMNPEFADQIKQLDKEASYYRDECG 203
Score = 37.9 bits (84), Expect = 0.040
Identities = 26/139 (18%), Positives = 62/139 (44%), Gaps = 6/139 (4%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 73
E D ++ E + D + + ++ +++ KK+A ++ + L K K Q +++
Sbjct: 208 EVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRR 267
Query: 74 KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS-ADENNRMCKVLEN 132
+E + + +++++ LEK+ + + +L QQS A++ + +
Sbjct: 268 REDSMADNSQHL-----QIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIE 322
Query: 133 RAQQDEERMDQLTNQLKEA 151
R +Q EE ++ L A
Sbjct: 323 RRKQLEEILEMKQEALLAA 341
Score = 33.1 bits (72), Expect = 1.1
Identities = 26/129 (20%), Positives = 62/129 (48%), Gaps = 9/129 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D + + ++ ++ EK++ K E+ +D N + + + +KK AQ+ E++
Sbjct: 209 VDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRR 268
Query: 61 KN---------KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 111
++ ++E+ LE+ ++L AT+A +A+ + + + E L +
Sbjct: 269 EDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLE 328
Query: 112 KLLEAQQSA 120
++LE +Q A
Sbjct: 329 EILEMKQEA 337
>AY847595-1|AAW32538.1| 664|Homo sapiens lamin A/C transcript
variant 1 protein.
Length = 664
Score = 56.4 bits (130), Expect = 1e-07
Identities = 66/276 (23%), Positives = 109/276 (39%), Gaps = 11/276 (3%)
Query: 10 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
A + E +A D+ ++ L KV EE +EL+ + + E DLI + +L+
Sbjct: 80 AYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEA 139
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL-EAQQSADENNRMCK 128
L KE L+ +E L ++ + + K E G A+++L E + NR+
Sbjct: 140 LLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVGAENRLQT 199
Query: 129 VLENRAQQDEERMDQL--TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA-EDRVKS 185
+ E Q ++L T + E RL+ D +GK E +LA EL ED+V+
Sbjct: 200 MKEELDFQKNIYSEELRETKRRHETRLVEID-NGKQREFESRLADALQELRAQHEDQVEQ 258
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKT 245
ELE K L + S E+ + V K
Sbjct: 259 YK---KELE---KTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQ 312
Query: 246 VKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ + ++ LED L +D + L E + AE+
Sbjct: 313 LAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEM 348
Score = 34.3 bits (75), Expect = 0.49
Identities = 51/223 (22%), Positives = 98/223 (43%), Gaps = 33/223 (14%)
Query: 1 MDAIKKKMQAMKLEK-DNAMDKAD-------TCEQQARDANLRAEKVNEEVRELQKKLAQ 52
++ KK+++ K DNA A+ ++ + + +R + ++ ++ +LQK+LA
Sbjct: 256 VEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAA 315
Query: 53 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
E L ++ + ++ + + L E E+A + ++QQ ++ Q+
Sbjct: 316 KEAKL---RDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY-----------QE 361
Query: 113 LLEAQQSAD-ENNRMCKVLENRAQQDEERM---DQLTNQLKEARLLAEDAD---GKSDEV 165
LL+ + + D E + K+LE +EER+ T+Q R + + G S
Sbjct: 362 LLDIKLALDMEIHAYRKLLEG----EEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTK 417
Query: 166 SRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
RKL E ++ SG + E++EE K V KS E
Sbjct: 418 KRKLESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNE 460
>AL138742-1|CAI22698.1| 1325|Homo sapiens KIAA1009 protein.
Length = 1325
Score = 56.4 bits (130), Expect = 1e-07
Identities = 60/269 (22%), Positives = 115/269 (42%), Gaps = 8/269 (2%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN-EEVRELQKKLAQVEEDLILNKNK 63
K+K KLE+ + + + + L+A+ + EE + Q+ L E + K
Sbjct: 565 KEKELENKLEELKKQQEKELFKLNQDNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEK 624
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L+Q K+++E+E L + E L +V+ ++E +K+EER Q L S E
Sbjct: 625 LKQIQKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQSLFSEVASLKEQ 684
Query: 124 NRMCKVLENRAQQDEERMDQ-LTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
+ L + E +Q T+ L E R+ ++ D +++ R L + LEV ++
Sbjct: 685 MHKSRFLSQVVEDSEPTRNQNFTDLLAELRMAQKEKDSLLEDIKR-LKQDKQALEVDFEK 743
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ---RVEEFXXXXXXXXXXXXXXXXXX 239
+K + ++ V G L +++ EE Q R+++
Sbjct: 744 MKK--ERDQAKDQIAYVTGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDALRL 801
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYK 268
+ ++KL+ E+++L+ E G R K
Sbjct: 802 REANEEIEKLKLEIEKLKAESGNPSIRQK 830
>AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golgin
subfamily a, 4 variant protein.
Length = 1310
Score = 56.4 bits (130), Expect = 1e-07
Identities = 63/292 (21%), Positives = 128/292 (43%), Gaps = 21/292 (7%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQA---RDANLRAE-KVNEEVRELQKKLAQVEED--LI 58
K++ + EK+ ++ D Q+ +D ++ + K+ ++R+ + + Q+E+D ++
Sbjct: 337 KEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMV 396
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
+ + K Q ++ LE KE+++ + + + + +++ E EKSE + +K L Q
Sbjct: 397 IAETK-RQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQ 455
Query: 119 SADENNRMCKV-----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE--VSRKLAF 171
+E R K ++ + EE L +L + D KS E +++
Sbjct: 456 KTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKL 515
Query: 172 VEDELEVAEDRV-KSGDAKISELEEELKVVGNSLKS--LEVSEEKANQR---VEEFXXXX 225
E EL E + K + E +E++KV +S L++S+EK Q +EE
Sbjct: 516 HEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQK 575
Query: 226 XXXXXXXXXXXXXXXXXXKTVKKLQKEVD-RLEDELGINKDRYKSLADEMDS 276
+T + E++ LE L NK++ K LA +++
Sbjct: 576 KAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEA 627
Score = 48.0 bits (109), Expect = 4e-05
Identities = 49/217 (22%), Positives = 99/217 (45%), Gaps = 12/217 (5%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
+K+ A LE A + A + +R + E++ E + E+ ++ ++ + + + + KL
Sbjct: 1027 EKQFNAKMLEMAQA-NSAGISDAVSRLETNQKEQI-ESLTEVHRR--ELNDVISIWEKKL 1082
Query: 65 EQANKDLEE-KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
Q ++L+E E QL E EVA L +K+ EK E K +Q N
Sbjct: 1083 NQQAEELQEIHEIQLQEKEQEVAELKQKILLF--GCEKEEMNKEITWLKEEGVKQDTTLN 1140
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
L+ + +Q ++ L + + E + ++ ++ F++++L +
Sbjct: 1141 E-----LQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLA 1195
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ K+SEL +LK +SL+ S EK+N+ +E+
Sbjct: 1196 EEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLED 1232
Score = 40.7 bits (91), Expect = 0.006
Identities = 37/187 (19%), Positives = 89/187 (47%), Gaps = 15/187 (8%)
Query: 48 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 107
K L +++ + +N L++ + ++ ++Q T +E AL ++ + ++LEK ++
Sbjct: 310 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHM 369
Query: 108 TAQQKLLEAQQSAD------ENNRMCKVLENRAQ------QDEERMDQLTNQLKEARLLA 155
+ KL+ + A E ++ + E + Q EE + QL +++K+
Sbjct: 370 AEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQG 429
Query: 156 EDADGKSDEVSRKLAF--VEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E+ + E S + AF +E L A+ ++ +E++E++K + + + +S ++
Sbjct: 430 EEL-REQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQ 488
Query: 214 ANQRVEE 220
RV++
Sbjct: 489 ELSRVKQ 495
Score = 39.9 bits (89), Expect = 0.010
Identities = 28/87 (32%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
Query: 2 DAIKKKMQAMKLEKD-NAMDKADT-CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
D K K KLE D N K +T ++Q + + AE+ +V EL KL +E+
Sbjct: 1159 DETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQS 1218
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVA 86
K+ E++NK LE+K + E+A
Sbjct: 1219 LKSSHEKSNKSLEDKSLEFKKLSEELA 1245
Score = 38.3 bits (85), Expect = 0.030
Identities = 44/199 (22%), Positives = 86/199 (43%), Gaps = 23/199 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +K + MK E + MD+ QQ D+ ++ +V+ ++ +K L
Sbjct: 738 LSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS--IQRTEKAL---------- 785
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K+++ Q L+E++K L +A V+ +E D+++SE A KL Q
Sbjct: 786 KDQINQLELLLKERDKHLKEHQAH-------VENLEADIKRSEGELQQASAKLDVFQSYQ 838
Query: 121 DENNRMCKVLENR-AQQDEERMDQLTNQLKEARLLAEDADGKSD---EVSRKLAFVEDEL 176
+ K E + AQ ++ +D T ++ + +AE K D E+ V+D +
Sbjct: 839 SATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLM 898
Query: 177 EVAEDRVKSGDAKISELEE 195
+ E + + K+ L +
Sbjct: 899 QQLEKQNSEMEQKVKSLTQ 917
Score = 36.7 bits (81), Expect = 0.092
Identities = 38/212 (17%), Positives = 96/212 (45%), Gaps = 6/212 (2%)
Query: 4 IKKKMQAMKLEKDNAM-DKADTCEQQARDANLRA-EKVNEEVRELQKKLAQVEEDLILNK 61
++K + + EK+ + DK + + N + EK++ + EL+ +++ E ++ +
Sbjct: 673 MEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSE-VLKAR 731
Query: 62 NKLEQANKDLEEK-EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+KLE+ L+++ +K EA++ QQ + + K E S +K L+ Q
Sbjct: 732 HKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQ--I 789
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
++ + K + ++ + ++ L +K + + A K D + ++ + E
Sbjct: 790 NQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYE 849
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
+++ K+ +LE E ++ + +E ++
Sbjct: 850 EQLAQLQQKLLDLETERILLTKQVAEVEAQKK 881
Score = 36.3 bits (80), Expect = 0.12
Identities = 34/186 (18%), Positives = 90/186 (48%), Gaps = 2/186 (1%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK-EKQLTATEAEVAALNRKVQQI 95
E ++ E+ E+ K ++EE+L + K++ ++ ++LE K ++Q + +V ++ ++ +
Sbjct: 718 ESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS 777
Query: 96 EEDLEKS-EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 154
+ EK+ +++ + L E + E+ + LE ++ E + Q + +L +
Sbjct: 778 IQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSY 837
Query: 155 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
++ +LA ++ +L E +++E+E + K V L + ++ +
Sbjct: 838 QSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDL 897
Query: 215 NQRVEE 220
Q++E+
Sbjct: 898 MQQLEK 903
Score = 35.1 bits (77), Expect = 0.28
Identities = 57/287 (19%), Positives = 127/287 (44%), Gaps = 22/287 (7%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED------ 56
++++++ +K E + M K+ EQ A+ L +++ + +EL KKL E +
Sbjct: 485 SLQQELSRVKQEVVDVMKKSSE-EQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMK 543
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV-QQIEEDLEKSEERSGTAQQKLLE 115
+ L K++ E K +EKE+Q + E+ + + + E L ++ + T + ++LE
Sbjct: 544 VALEKSQSEYL-KISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILE 602
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQL-KEARLLAEDADGKSDEVSRKL-AFVE 173
+ S +++ + K N+++ ++ N+ KE ++ E + + + + A
Sbjct: 603 LESSLEKSLQENK---NQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWT 659
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXX 233
++L+V + + ++ K+ E E+ K LK E+ + +EE
Sbjct: 660 EKLQVLKQQYQTEMEKLREKCEQEKET--LLKDKEIIFQA---HIEEMNEKTLEKLDVKQ 714
Query: 234 XXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
V K + +LE+EL + KD+ + E+++ E
Sbjct: 715 TELESLSSELSEVLKARH---KLEEELSVLKDQTDKMKQELEAKMDE 758
Score = 34.3 bits (75), Expect = 0.49
Identities = 33/204 (16%), Positives = 87/204 (42%), Gaps = 9/204 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K+K+ EK+ + +++ + ++ E++++ + + +D K
Sbjct: 1107 LKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAH 1166
Query: 64 LEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEEDLEKSEERSGTAQQKLLEA 116
LE+ DL + K+ T + ++ L RKV ++ L+ ++E + + ++
Sbjct: 1167 LEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKS 1226
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL--LAEDADGKSDEVSRKLAFVED 174
+S ++ + K L + + T L EA+ L + K++ + +++ +
Sbjct: 1227 NKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQH 1286
Query: 175 ELEVAEDRVKSGDAKISELEEELK 198
++ + +SELE +L+
Sbjct: 1287 RTTKVKEALLIKTCTVSELEAQLR 1310
>AB023226-1|BAA76853.2| 1345|Homo sapiens KIAA1009 protein protein.
Length = 1345
Score = 56.4 bits (130), Expect = 1e-07
Identities = 60/269 (22%), Positives = 115/269 (42%), Gaps = 8/269 (2%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN-EEVRELQKKLAQVEEDLILNKNK 63
K+K KLE+ + + + + L+A+ + EE + Q+ L E + K
Sbjct: 585 KEKELENKLEELKKQQEKELFKLNQDNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEK 644
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L+Q K+++E+E L + E L +V+ ++E +K+EER Q L S E
Sbjct: 645 LKQIQKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQSLFSEVASLKEQ 704
Query: 124 NRMCKVLENRAQQDEERMDQ-LTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
+ L + E +Q T+ L E R+ ++ D +++ R L + LEV ++
Sbjct: 705 MHKSRFLSQVVEDSEPTRNQNFTDLLAELRMAQKEKDSLLEDIKR-LKQDKQALEVDFEK 763
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ---RVEEFXXXXXXXXXXXXXXXXXX 239
+K + ++ V G L +++ EE Q R+++
Sbjct: 764 MKK--ERDQAKDQIAYVTGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDALRL 821
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRYK 268
+ ++KL+ E+++L+ E G R K
Sbjct: 822 REANEEIEKLKLEIEKLKAESGNPSIRQK 850
Score = 34.3 bits (75), Expect = 0.49
Identities = 46/210 (21%), Positives = 92/210 (43%), Gaps = 10/210 (4%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL-EQANKDLE 72
+K + D+C Q D+ L N+E + L K Q ED L EQ
Sbjct: 525 KKSENPTETDSCIQFQTDS-LGYCGENKEKKLLMFKRVQEAEDKWRGAQALIEQIKATFS 583
Query: 73 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 132
EKEK+L E ++ L + Q E++L K + + Q KL +++ ++ R E
Sbjct: 584 EKEKEL---ENKLEELKK---QQEKELFKLNQDNYILQAKLSSFEET-NKKQRWLHFGEA 636
Query: 133 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV-KSGDAKIS 191
E++ Q+ +++E L + +++ + ++ ++++ + E+R+ K + S
Sbjct: 637 ADPVTGEKLKQIQKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQSLFS 696
Query: 192 ELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
E+ + + S +V E+ R + F
Sbjct: 697 EVASLKEQMHKSRFLSQVVEDSEPTRNQNF 726
Score = 30.7 bits (66), Expect = 6.1
Identities = 38/169 (22%), Positives = 69/169 (40%), Gaps = 9/169 (5%)
Query: 34 LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 93
L+ +K ++ V E++++ A+ + L + L + LE E L +E ++L +
Sbjct: 9 LKTKKTSQPVMEIEEESAEKIQFLKSSGTSLLSTDS-LETNE--LVVSELNHSSLGVGLD 65
Query: 94 QIEEDLEKSE-----ERSGTAQQKLLEAQQSADENNRM-CKVLENRAQQDEERMDQLTNQ 147
+EE EK + E+ T+ + D N+ K L E D+ N+
Sbjct: 66 TLEEQEEKEQFFARLEKGLTSSIDYSRLNKELDSNDSTHFKALHINQANAELTDDEHENE 125
Query: 148 LKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 196
K L +D DE +DE +++ KS + + EEE
Sbjct: 126 SKHEELAENYSDDFEDEYVGAPLTTKDEEMPSKENSKSEKISVPKQEEE 174
>D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein.
Length = 2067
Score = 56.0 bits (129), Expect = 1e-07
Identities = 44/180 (24%), Positives = 81/180 (45%), Gaps = 8/180 (4%)
Query: 48 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI-------EEDLE 100
K A + ++ KN+LE++ K A E E+ L+ ++ I EE L
Sbjct: 1689 KNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1748
Query: 101 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+ + Q +L E Q+ +E + K +A +D +++ L QL+EA ++
Sbjct: 1749 RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQE 1808
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
K + ++ F+E + V + V +AKI ELE L+ +K LE + + +E+
Sbjct: 1809 KLQALQSQVEFLEQSM-VDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEK 1867
Score = 54.0 bits (124), Expect = 6e-07
Identities = 51/218 (23%), Positives = 106/218 (48%), Gaps = 14/218 (6%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR--ELQKKLAQVEEDLILN---- 60
++Q KL + + E++ R + + +EE + +LQ++ Q E+D++L
Sbjct: 1451 ELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS 1510
Query: 61 -KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
K +LE+ + D+ +++ + EAE+ ++ + + E L K +++ + K+ + ++
Sbjct: 1511 LKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEE 1570
Query: 120 ADENNRMCKVLEN---RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
DE ++LE R + + ERM Q ++ E+R E+ + +KL +E +L
Sbjct: 1571 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESR--DEEVEEARQSCQKKLKQMEVQL 1628
Query: 177 EVA-EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E ED+ K K ELE +L + + + + EK
Sbjct: 1629 EEEYEDKQKVLREK-RELEGKLATLSDQVNRRDFESEK 1665
Score = 53.2 bits (122), Expect = 1e-06
Identities = 56/228 (24%), Positives = 105/228 (46%), Gaps = 11/228 (4%)
Query: 2 DAIKKKMQAMKL--EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
+A ++K+Q KL EKD + +A + +QQ + ++ ++V L+ +L +
Sbjct: 1486 EAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESK 1545
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLEA 116
++ L + K L + E ++ E E+ +Q +E+ LE ER K +E+
Sbjct: 1546 DEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMES 1605
Query: 117 Q-QSADENNRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
+ + +E + C K L+ Q EE + L+E R L SD+V+R+ E
Sbjct: 1606 RDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRR--DFES 1663
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKS-LEVSEEKANQRVEEF 221
E + +D +K A +++ + L + NS S E+++ K EF
Sbjct: 1664 EKRLRKD-LKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEF 1710
Score = 52.8 bits (121), Expect = 1e-06
Identities = 57/281 (20%), Positives = 132/281 (46%), Gaps = 24/281 (8%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL--ILN 60
A K +AM++E ++ + D + + ++ E E+Q +L + +ED+ ++
Sbjct: 1714 AAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMK 1773
Query: 61 KNK--LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE-----------ERSG 107
K+K + QA++DL Q+ +A++ N++ Q+++E L+ + ++S
Sbjct: 1774 KHKAAVAQASRDLA----QINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSL 1829
Query: 108 TAQQ--KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE- 164
++Q K+ E + + K LE+ A + +E M++LT + ++ R+ AE+ + + ++
Sbjct: 1830 VSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-RDQRIAAENREKEQNKR 1888
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXX 224
+ R+L ++E+ + K ELE +L+ + + +SL+ + A +R+ +
Sbjct: 1889 LQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDL-QA 1947
Query: 225 XXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKD 265
V K QK ++LE + ++ +
Sbjct: 1948 AIEDEMESDENEDLINSLQDMVTKYQKRKNKLEGDSDVDSE 1988
Score = 46.0 bits (104), Expect = 2e-04
Identities = 50/226 (22%), Positives = 102/226 (45%), Gaps = 20/226 (8%)
Query: 2 DAIKKKMQAMKLEKDNA-MDKADTCEQQARDAN------LRAEKVNEEVRELQKKLAQVE 54
DA+KK+M+ M++E A + +A + D + L+ E+ EV +K+L Q
Sbjct: 1347 DALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEF 1406
Query: 55 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
ED K ++EQ NK + E++L +A+ R +QQ++ +K + + Q L
Sbjct: 1407 ED----KLEVEQQNK--RQLERRLGDLQADSEESQRALQQLK---KKCQRLTAELQDTKL 1457
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
+ N+ LE + ++ + + Q + + +L E + D + + ++
Sbjct: 1458 HLEGQQVRNHE----LEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ 1513
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+LE + + K+ LE EL+ + + E S K +++ +
Sbjct: 1514 QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRD 1559
Score = 45.2 bits (102), Expect = 3e-04
Identities = 42/198 (21%), Positives = 88/198 (44%), Gaps = 12/198 (6%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
QQ + L E+ N+ R+L+++L ++ D ++ L+Q K + +L T+ +
Sbjct: 1403 QQEFEDKLEVEQQNK--RQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLE 1460
Query: 87 ALNRKVQQIEE-----DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
+ ++E+ D E S+ ++KL + +++ + + + Q +E+ M
Sbjct: 1461 GQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDM 1520
Query: 142 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 201
D K L AE D S E E L + +++ +AK+ + EEEL
Sbjct: 1521 DIAGFTQKVVSLEAELQDISSQESKD-----EASLAKVKKQLRDLEAKVKDQEEELDEQA 1575
Query: 202 NSLKSLEVSEEKANQRVE 219
+++ LE ++ + +E
Sbjct: 1576 GTIQMLEQAKLRLEMEME 1593
Score = 41.9 bits (94), Expect = 0.002
Identities = 36/191 (18%), Positives = 85/191 (44%), Gaps = 4/191 (2%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
++ KL + M++ + +++ R E+V E + QKKL Q+E L ++
Sbjct: 1581 LEQAKLRLEMEMERMR--QTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKV 1638
Query: 68 NKDLEEKEKQLTATEAEVAALN-RKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
++ E E +L +V + +++ +DL++++ AQ L + SA +
Sbjct: 1639 LREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREI 1698
Query: 127 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
+ L+N+ ++ E K + ED + D++++ +E++L +
Sbjct: 1699 AQ-LKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEI 1757
Query: 187 DAKISELEEEL 197
++ E +E++
Sbjct: 1758 QNRLEEDQEDM 1768
Score = 39.5 bits (88), Expect = 0.013
Identities = 33/141 (23%), Positives = 67/141 (47%), Gaps = 9/141 (6%)
Query: 28 QARDANLRAE-KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
+ RD + AE + E+ + LQ++L +E++ E A K+ E K+ E ++
Sbjct: 1870 EERDQRIAAENREKEQNKRLQRQLRDTKEEMG------ELARKEAEASRKK-HELEMDLE 1922
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+L Q ++ DL+ + +R G Q + E + +DEN + L++ + ++R ++L
Sbjct: 1923 SLEAANQSLQADLKLAFKRIGDLQAAI-EDEMESDENEDLINSLQDMVTKYQKRKNKLEG 1981
Query: 147 QLKEARLLAEDADGKSDEVSR 167
L + DG +S+
Sbjct: 1982 DSDVDSELEDRVDGVKSWLSK 2002
Score = 38.3 bits (85), Expect = 0.030
Identities = 55/239 (23%), Positives = 111/239 (46%), Gaps = 29/239 (12%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRA--EKVNEEVRELQKKLAQVEEDLI 58
+D KK++Q + E +++ + + + R +L+A E+ +++L+KK ++ +L
Sbjct: 1395 VDFTKKRLQ-QEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ 1453
Query: 59 LNKNKLE---QANKDLEEKEKQLTA------TEAEVAALNRKVQQIEEDLEKSEERSGTA 109
K LE N +LE+K+++ + EA+ L R+ Q E+D+ +E S
Sbjct: 1454 DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS--L 1511
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQ-------QDEERMDQLTNQLKEARLLAEDADGKS 162
+Q+L E + LE Q +DE + ++ QL++ +D + +
Sbjct: 1512 KQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEEL 1571
Query: 163 DEVSRKLAFVED---ELEVAEDRV-----KSGDAKISELEEELKVVGNSLKSLEVSEEK 213
DE + + +E LE+ +R+ K +++ E+EE + LK +EV E+
Sbjct: 1572 DEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1630
Score = 33.1 bits (72), Expect = 1.1
Identities = 38/220 (17%), Positives = 98/220 (44%), Gaps = 9/220 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQVEEDLILNKN 62
++ K++ + E++ +D E +R + L +E +E E +L E L
Sbjct: 1279 LRSKLEKAEKERNELRLNSDRLE--SRISELTSELTDERNTGESASQLLDAETAERLRAE 1336
Query: 63 K-LEQANKDLEEKEKQLTATEAEVAALNR-KVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K +++ + +KQ+ E EV + +I +++ ++ G + K A +
Sbjct: 1337 KEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVD-DDDAGGEWRLKYERAVREV 1395
Query: 121 D-ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
D R+ + E++ + +++ QL +L + + +E++ ++ +K + EL+
Sbjct: 1396 DFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDT 1455
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ ++ + ELE++ + + L + EE ++++
Sbjct: 1456 KLHLEGQQVRNHELEKKQRRFDSELS--QAHEEAQREKLQ 1493
>BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein.
Length = 2002
Score = 56.0 bits (129), Expect = 1e-07
Identities = 44/180 (24%), Positives = 81/180 (45%), Gaps = 8/180 (4%)
Query: 48 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI-------EEDLE 100
K A + ++ KN+LE++ K A E E+ L+ ++ I EE L
Sbjct: 1639 KNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1698
Query: 101 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+ + Q +L E Q+ +E + K +A +D +++ L QL+EA ++
Sbjct: 1699 RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQE 1758
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
K + ++ F+E + V + V +AKI ELE L+ +K LE + + +E+
Sbjct: 1759 KLQALQSQVEFLEQSM-VDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEK 1817
Score = 55.6 bits (128), Expect = 2e-07
Identities = 60/290 (20%), Positives = 136/290 (46%), Gaps = 24/290 (8%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL--ILN 60
A K +AM++E ++ + D + + ++ E E+Q +L + +ED+ ++
Sbjct: 1664 AAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMK 1723
Query: 61 KNK--LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE-----------ERSG 107
K+K + QA++DL Q+ +A++ N++ Q+++E L+ + ++S
Sbjct: 1724 KHKAAVAQASRDLA----QINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSL 1779
Query: 108 TAQQ--KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE- 164
++Q K+ E + + K LE+ A + +E M++LT + ++ R+ AE+ + + ++
Sbjct: 1780 VSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-RDQRIAAENREKEQNKR 1838
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXX 224
+ R+L ++E+ + K ELE +L+ + + +SL+ + A +R+ +
Sbjct: 1839 LQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAA 1898
Query: 225 XXXXXXXXXXXXXXXXXXXKTV-KKLQKEVDRLEDELGINKDRYKSLADE 273
V +L+ VD ++ L NK K+ +D+
Sbjct: 1899 IEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSKAASDD 1948
Score = 51.6 bits (118), Expect = 3e-06
Identities = 52/226 (23%), Positives = 108/226 (47%), Gaps = 14/226 (6%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR--ELQKKLAQVEEDLILN---- 60
++Q KL + + E++ R + + +EE + +LQ++ Q E+D++L
Sbjct: 1438 ELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS 1497
Query: 61 -KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
K +LE+ + D+ +++ + EAE+ ++ + + E L K +++ + K+ + ++
Sbjct: 1498 LKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEE 1557
Query: 120 ADENNRMCKVLENRAQQD---EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
DE ++LE Q + EE + L+E R L SD+V+R+ E E
Sbjct: 1558 LDEQAGTIQMLEQLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRR--DFESEK 1615
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKS-LEVSEEKANQRVEEF 221
+ +D +K A +++ + L + NS S E+++ K EF
Sbjct: 1616 RLRKD-LKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEF 1660
Score = 47.2 bits (107), Expect = 7e-05
Identities = 50/233 (21%), Positives = 107/233 (45%), Gaps = 16/233 (6%)
Query: 2 DAIKKKMQAMKL--EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
+A ++K+Q KL EKD + +A + +QQ + ++ ++V L+ +L +
Sbjct: 1473 EAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESK 1532
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE--DLEKSEERSGTAQQKLLEAQ 117
++ L + K L + E ++ E E+ +Q +E+ +E E +QK+L +
Sbjct: 1533 DEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQLKQMEVQLEEEYEDKQKVLREK 1592
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV------SRKLAF 171
+ + ++ + + ++D E +L LK + L DA D + R++A
Sbjct: 1593 RELE--GKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQ 1650
Query: 172 VEDELEVAE----DRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
++++LE +E VK+ A E+E+ + + K+ EE+ ++ E
Sbjct: 1651 LKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1703
Score = 46.8 bits (106), Expect = 9e-05
Identities = 44/200 (22%), Positives = 89/200 (44%), Gaps = 12/200 (6%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
QQ + L E+ N+ R+L+++L ++ D ++ L+Q K + +L T+ +
Sbjct: 1390 QQEFEDKLEVEQQNK--RQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLE 1447
Query: 87 ALNRKVQQIEE-----DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
+ ++E+ D E S+ ++KL + +++ + + + Q +E+ M
Sbjct: 1448 GQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDM 1507
Query: 142 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 201
D K L AE D S E E L + +++ +AK+ + EEEL
Sbjct: 1508 DIAGFTQKVVSLEAELQDISSQESKD-----EASLAKVKKQLRDLEAKVKDQEEELDEQA 1562
Query: 202 NSLKSLEVSEEKANQRVEEF 221
+++ LE ++ Q EE+
Sbjct: 1563 GTIQMLEQLKQMEVQLEEEY 1582
Score = 46.0 bits (104), Expect = 2e-04
Identities = 50/226 (22%), Positives = 102/226 (45%), Gaps = 20/226 (8%)
Query: 2 DAIKKKMQAMKLEKDNA-MDKADTCEQQARDAN------LRAEKVNEEVRELQKKLAQVE 54
DA+KK+M+ M++E A + +A + D + L+ E+ EV +K+L Q
Sbjct: 1334 DALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEF 1393
Query: 55 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
ED K ++EQ NK + E++L +A+ R +QQ++ +K + + Q L
Sbjct: 1394 ED----KLEVEQQNK--RQLERRLGDLQADSEESQRALQQLK---KKCQRLTAELQDTKL 1444
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
+ N+ LE + ++ + + Q + + +L E + D + + ++
Sbjct: 1445 HLEGQQVRNHE----LEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ 1500
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+LE + + K+ LE EL+ + + E S K +++ +
Sbjct: 1501 QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRD 1546
Score = 37.5 bits (83), Expect = 0.053
Identities = 35/180 (19%), Positives = 83/180 (46%), Gaps = 10/180 (5%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
++Q RD + + EE+ E Q Q+ E L + +LE+ +D ++ ++ E ++
Sbjct: 1541 KKQLRDLEAKVKDQEEELDE-QAGTIQMLEQLKQMEVQLEEEYEDKQKVLREKRELEGKL 1599
Query: 86 AALNRKV--------QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQD 137
A L+ +V +++ +DL++++ AQ L + SA + + L+N+ ++
Sbjct: 1600 ATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQ-LKNQLEES 1658
Query: 138 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 197
E K + ED + D++++ +E++L + ++ E +E++
Sbjct: 1659 EFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDM 1718
Score = 33.1 bits (72), Expect = 1.1
Identities = 38/220 (17%), Positives = 98/220 (44%), Gaps = 9/220 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQVEEDLILNKN 62
++ K++ + E++ +D E +R + L +E +E E +L E L
Sbjct: 1266 LRSKLEKAEKERNELRLNSDRLE--SRISELTSELTDERNTGESASQLLDAETAERLRAE 1323
Query: 63 K-LEQANKDLEEKEKQLTATEAEVAALNR-KVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K +++ + +KQ+ E EV + +I +++ ++ G + K A +
Sbjct: 1324 KEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVD-DDDAGGEWRLKYERAVREV 1382
Query: 121 D-ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
D R+ + E++ + +++ QL +L + + +E++ ++ +K + EL+
Sbjct: 1383 DFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDT 1442
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ ++ + ELE++ + + L + EE ++++
Sbjct: 1443 KLHLEGQQVRNHELEKKQRRFDSELS--QAHEEAQREKLQ 1480
>AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit
SP-R210 alphaS protein.
Length = 1581
Score = 56.0 bits (129), Expect = 1e-07
Identities = 44/180 (24%), Positives = 81/180 (45%), Gaps = 8/180 (4%)
Query: 48 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI-------EEDLE 100
K A + ++ KN+LE++ K A E E+ L+ ++ I EE L
Sbjct: 1218 KNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1277
Query: 101 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+ + Q +L E Q+ +E + K +A +D +++ L QL+EA ++
Sbjct: 1278 RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQE 1337
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
K + ++ F+E + V + V +AKI ELE L+ +K LE + + +E+
Sbjct: 1338 KLQALQSQVEFLEQSM-VDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEK 1396
Score = 55.6 bits (128), Expect = 2e-07
Identities = 60/290 (20%), Positives = 136/290 (46%), Gaps = 24/290 (8%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL--ILN 60
A K +AM++E ++ + D + + ++ E E+Q +L + +ED+ ++
Sbjct: 1243 AAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMK 1302
Query: 61 KNK--LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE-----------ERSG 107
K+K + QA++DL Q+ +A++ N++ Q+++E L+ + ++S
Sbjct: 1303 KHKAAVAQASRDLA----QINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSL 1358
Query: 108 TAQQ--KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE- 164
++Q K+ E + + K LE+ A + +E M++LT + ++ R+ AE+ + + ++
Sbjct: 1359 VSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-RDQRIAAENREKEQNKR 1417
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXX 224
+ R+L ++E+ + K ELE +L+ + + +SL+ + A +R+ +
Sbjct: 1418 LQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAA 1477
Query: 225 XXXXXXXXXXXXXXXXXXXKTV-KKLQKEVDRLEDELGINKDRYKSLADE 273
V +L+ VD ++ L NK K+ +D+
Sbjct: 1478 IEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSKAASDD 1527
Score = 54.0 bits (124), Expect = 6e-07
Identities = 51/218 (23%), Positives = 106/218 (48%), Gaps = 14/218 (6%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR--ELQKKLAQVEEDLILN---- 60
++Q KL + + E++ R + + +EE + +LQ++ Q E+D++L
Sbjct: 980 ELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS 1039
Query: 61 -KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
K +LE+ + D+ +++ + EAE+ ++ + + E L K +++ + K+ + ++
Sbjct: 1040 LKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEE 1099
Query: 120 ADENNRMCKVLEN---RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
DE ++LE R + + ERM Q ++ E+R E+ + +KL +E +L
Sbjct: 1100 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESR--DEEVEEARQSCQKKLKQMEVQL 1157
Query: 177 EVA-EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E ED+ K K ELE +L + + + + EK
Sbjct: 1158 EEEYEDKQKVLREK-RELEGKLATLSDQVNRRDFESEK 1194
Score = 53.2 bits (122), Expect = 1e-06
Identities = 56/228 (24%), Positives = 105/228 (46%), Gaps = 11/228 (4%)
Query: 2 DAIKKKMQAMKL--EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
+A ++K+Q KL EKD + +A + +QQ + ++ ++V L+ +L +
Sbjct: 1015 EAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESK 1074
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLEA 116
++ L + K L + E ++ E E+ +Q +E+ LE ER K +E+
Sbjct: 1075 DEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMES 1134
Query: 117 Q-QSADENNRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
+ + +E + C K L+ Q EE + L+E R L SD+V+R+ E
Sbjct: 1135 RDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRR--DFES 1192
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKS-LEVSEEKANQRVEEF 221
E + +D +K A +++ + L + NS S E+++ K EF
Sbjct: 1193 EKRLRKD-LKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEF 1239
Score = 46.0 bits (104), Expect = 2e-04
Identities = 50/226 (22%), Positives = 102/226 (45%), Gaps = 20/226 (8%)
Query: 2 DAIKKKMQAMKLEKDNA-MDKADTCEQQARDAN------LRAEKVNEEVRELQKKLAQVE 54
DA+KK+M+ M++E A + +A + D + L+ E+ EV +K+L Q
Sbjct: 876 DALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEF 935
Query: 55 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
ED K ++EQ NK + E++L +A+ R +QQ++ +K + + Q L
Sbjct: 936 ED----KLEVEQQNK--RQLERRLGDLQADSEESQRALQQLK---KKCQRLTAELQDTKL 986
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
+ N+ LE + ++ + + Q + + +L E + D + + ++
Sbjct: 987 HLEGQQVRNHE----LEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ 1042
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+LE + + K+ LE EL+ + + E S K +++ +
Sbjct: 1043 QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRD 1088
Score = 45.2 bits (102), Expect = 3e-04
Identities = 42/198 (21%), Positives = 88/198 (44%), Gaps = 12/198 (6%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
QQ + L E+ N+ R+L+++L ++ D ++ L+Q K + +L T+ +
Sbjct: 932 QQEFEDKLEVEQQNK--RQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLE 989
Query: 87 ALNRKVQQIEE-----DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
+ ++E+ D E S+ ++KL + +++ + + + Q +E+ M
Sbjct: 990 GQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDM 1049
Query: 142 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 201
D K L AE D S E E L + +++ +AK+ + EEEL
Sbjct: 1050 DIAGFTQKVVSLEAELQDISSQESKD-----EASLAKVKKQLRDLEAKVKDQEEELDEQA 1104
Query: 202 NSLKSLEVSEEKANQRVE 219
+++ LE ++ + +E
Sbjct: 1105 GTIQMLEQAKLRLEMEME 1122
Score = 41.9 bits (94), Expect = 0.002
Identities = 36/191 (18%), Positives = 85/191 (44%), Gaps = 4/191 (2%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
++ KL + M++ + +++ R E+V E + QKKL Q+E L ++
Sbjct: 1110 LEQAKLRLEMEMERMR--QTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKV 1167
Query: 68 NKDLEEKEKQLTATEAEVAALN-RKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
++ E E +L +V + +++ +DL++++ AQ L + SA +
Sbjct: 1168 LREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREI 1227
Query: 127 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
+ L+N+ ++ E K + ED + D++++ +E++L +
Sbjct: 1228 AQ-LKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEI 1286
Query: 187 DAKISELEEEL 197
++ E +E++
Sbjct: 1287 QNRLEEDQEDM 1297
Score = 38.3 bits (85), Expect = 0.030
Identities = 55/239 (23%), Positives = 111/239 (46%), Gaps = 29/239 (12%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRA--EKVNEEVRELQKKLAQVEEDLI 58
+D KK++Q + E +++ + + + R +L+A E+ +++L+KK ++ +L
Sbjct: 924 VDFTKKRLQ-QEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ 982
Query: 59 LNKNKLE---QANKDLEEKEKQLTA------TEAEVAALNRKVQQIEEDLEKSEERSGTA 109
K LE N +LE+K+++ + EA+ L R+ Q E+D+ +E S
Sbjct: 983 DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS--L 1040
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQ-------QDEERMDQLTNQLKEARLLAEDADGKS 162
+Q+L E + LE Q +DE + ++ QL++ +D + +
Sbjct: 1041 KQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEEL 1100
Query: 163 DEVSRKLAFVED---ELEVAEDRV-----KSGDAKISELEEELKVVGNSLKSLEVSEEK 213
DE + + +E LE+ +R+ K +++ E+EE + LK +EV E+
Sbjct: 1101 DEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1159
Score = 33.1 bits (72), Expect = 1.1
Identities = 38/220 (17%), Positives = 98/220 (44%), Gaps = 9/220 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQVEEDLILNKN 62
++ K++ + E++ +D E +R + L +E +E E +L E L
Sbjct: 808 LRSKLEKAEKERNELRLNSDRLE--SRISELTSELTDERNTGESASQLLDAETAERLRAE 865
Query: 63 K-LEQANKDLEEKEKQLTATEAEVAALNR-KVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K +++ + +KQ+ E EV + +I +++ ++ G + K A +
Sbjct: 866 KEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVD-DDDAGGEWRLKYERAVREV 924
Query: 121 D-ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
D R+ + E++ + +++ QL +L + + +E++ ++ +K + EL+
Sbjct: 925 DFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDT 984
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ ++ + ELE++ + + L + EE ++++
Sbjct: 985 KLHLEGQQVRNHELEKKQRRFDSELS--QAHEEAQREKLQ 1022
>AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting citron
kinase protein.
Length = 2027
Score = 56.0 bits (129), Expect = 1e-07
Identities = 54/227 (23%), Positives = 102/227 (44%), Gaps = 12/227 (5%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
+++KK+ E ++ DK EQ+ + R +V + + + +L E L +
Sbjct: 446 SMEKKLLIKSKELQDSQDKCHKMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQ 505
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
L + ++ L EV+ + K Q+ D+ + + +++ +AQ +E
Sbjct: 506 DLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQ--VEE 563
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE--LEVAE 180
M LE R D ++L+E+RL AE+ K+ E KL +D+ EV E
Sbjct: 564 MRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKATECQHKLLKAKDQGKPEVGE 623
Query: 181 ----DRVKS-GDAKISELEEEL-KVVGNSLKSLEVSE--EKANQRVE 219
+++ + KI EL+E+L K V S ++ E+ + +A +R E
Sbjct: 624 YAKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAE 670
Score = 52.8 bits (121), Expect = 1e-06
Identities = 60/239 (25%), Positives = 106/239 (44%), Gaps = 21/239 (8%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-------VRELQKKLAQV 53
M A ++ + ++ +K +A E Q R + EK++ + + EL+ +L +V
Sbjct: 802 MKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREV 861
Query: 54 ----EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 109
EE + K +L + L+E+E QLTA +A AAL +++Q + +LE++ +
Sbjct: 862 SLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEE 921
Query: 110 QQKLL----EAQQSADENNRMCKV---LENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
Q L E Q+ D C V LE + Q E +L NQ ++A G +
Sbjct: 922 IQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGAN 981
Query: 163 DEVSRKLAFVED-ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
DE+ + + V+ E+ E ++ K + E LK L+ + E N + E
Sbjct: 982 DEIVQLRSEVDHLRREITEREMQLTSQK--QTMEALKTTCTMLEEQVMDLEALNDELLE 1038
Score = 46.4 bits (105), Expect = 1e-04
Identities = 47/198 (23%), Positives = 94/198 (47%), Gaps = 21/198 (10%)
Query: 7 KMQAMKLEKD--NAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
++ +LE+D +A ++D E + R++ L AE+ + E Q KL + ++ K ++
Sbjct: 565 RLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKATECQHKLLKAKDQ---GKPEV 621
Query: 65 -EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
E A + E+QL K+Q+++E LEK+ + S A + L +Q+ +
Sbjct: 622 GEYAKLEKINAEQQL------------KIQELQEKLEKAVKASTEATELLQNIRQAKERA 669
Query: 124 NRMCKVLENRAQQDEERMDQL--TNQLKEARLLAE-DADGKSDEVSRKLAFVEDELEVAE 180
R + L+NR E +L +L+E A+ A + +K E++++V +
Sbjct: 670 ERELEKLQNREDSSEGIRKKLVEAEELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLD 729
Query: 181 DRVKSGDAKISELEEELK 198
+++K A LE ++
Sbjct: 730 NQIKKDLADKETLENMMQ 747
Score = 45.6 bits (103), Expect = 2e-04
Identities = 57/263 (21%), Positives = 113/263 (42%), Gaps = 23/263 (8%)
Query: 11 MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE--DLILNKNKLEQAN 68
M+ ++ A +K +Q N ++ ++R L++++ ++ E L N + Q N
Sbjct: 746 MQRHEEEAHEKGKILSEQKAMINA----MDSKIRSLEQRIVELSEANKLAANSSLFTQRN 801
Query: 69 KDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
+E+ +Q E + L + +++EE LEK + + + +LLE + E
Sbjct: 802 MKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREV 861
Query: 124 NRMCKVLENRAQQDEERMD----QLTNQLKEARLLAEDADGKSDEVSRKLA--FVEDELE 177
+ LE+ Q+ E + QL+ Q +E++L A A + E + A +E+
Sbjct: 862 S-----LEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTA 916
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXX 237
AE+ +++ A E++ + + NS + EE+ NQ E+
Sbjct: 917 EAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDE 976
Query: 238 XXXXXXKTVKKLQKEVDRLEDEL 260
+ V +L+ EVD L E+
Sbjct: 977 ASGANDEIV-QLRSEVDHLRREI 998
Score = 44.4 bits (100), Expect = 5e-04
Identities = 42/190 (22%), Positives = 91/190 (47%), Gaps = 11/190 (5%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV---RELQKKL----AQVEE 55
A+++ ++ KL+ ++ DK + E++ + A + +++ REL+++L A++++
Sbjct: 1102 ALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQ 1161
Query: 56 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE--EDLEKSEERSGTAQQ-K 112
+ L KN + + + L+E + + E + L +++ I+ EK + +QQ K
Sbjct: 1162 QMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTK 1221
Query: 113 LLE-AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
L++ Q D+ + K L +R ++D Q+ Q E +L E + E+ L
Sbjct: 1222 LIDFLQAKMDQPAKKKKGLFSRRKEDPALPTQVPLQYNELKLALEKEKARCAELEEALQK 1281
Query: 172 VEDELEVAED 181
EL A +
Sbjct: 1282 TRIELRSARE 1291
Score = 43.6 bits (98), Expect = 8e-04
Identities = 47/217 (21%), Positives = 97/217 (44%), Gaps = 20/217 (9%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
D + +++ +L + KA C+ + A + + E +L+K A+ + + +
Sbjct: 583 DLYESELRESRLAAEEFKRKATECQHKLLKAKDQGKPEVGEYAKLEKINAEQQLKIQELQ 642
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 121
KLE+A K E + L + + ++ E L+ E+ S ++KL+EA++ +
Sbjct: 643 EKLEKAVKASTEATELL----QNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEE-LE 697
Query: 122 ENNRMCKV--------LENRAQQDEERMDQLTNQLK----EARLLAEDADGKSDEVSRKL 169
E +R +V L+ + Q EE++ L NQ+K + L +E K
Sbjct: 698 EKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEEAHEKG 757
Query: 170 AFVEDE---LEVAEDRVKSGDAKISELEEELKVVGNS 203
+ ++ + + +++S + +I EL E K+ NS
Sbjct: 758 KILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANS 794
Score = 36.3 bits (80), Expect = 0.12
Identities = 47/206 (22%), Positives = 99/206 (48%), Gaps = 20/206 (9%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ----ANKDLEEKEKQLTAT 81
+Q ++ L+AE +++++ +L+KK A +E + + KLE + LEE+ K
Sbjct: 1104 QQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQM 1163
Query: 82 EAEVAALNRKVQQIEEDLEKSE----ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQD 137
+ + + R Q ++E L++++ ERS Q LE Q + ++ +E Q
Sbjct: 1164 DLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQ--LENIQVLYSHEKV--KMEGTISQQ 1219
Query: 138 EERMDQLTNQLKEARLLAEDADGKSDE---VSRKLAFVEDELEVAEDRVKSGDAKISELE 194
+ +D L ++ + + + E + ++ +EL++A ++ K A+ +ELE
Sbjct: 1220 TKLIDFLQAKMDQPAKKKKGLFSRRKEDPALPTQVPLQYNELKLALEKEK---ARCAELE 1276
Query: 195 EELKVVGNSLKSLEVSEEKANQRVEE 220
E L+ L+S EE A+++ +
Sbjct: 1277 EALQKTRIELRS--AREEAAHRKATD 1300
Score = 35.5 bits (78), Expect = 0.21
Identities = 39/194 (20%), Positives = 73/194 (37%), Gaps = 4/194 (2%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
E Q R A E+ E E + L +++ + L + + + E+QL +
Sbjct: 901 ESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDN 960
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 145
A LN + + + L+ E SG A ++++ + D R E + ++ M+ L
Sbjct: 961 AELNNQNFYLSKQLD---EASG-ANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALK 1016
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
D + +DE+ K E V D + ++ EL+ L S
Sbjct: 1017 TTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRA 1076
Query: 206 SLEVSEEKANQRVE 219
+ ++ Q VE
Sbjct: 1077 RADQRITESRQVVE 1090
>AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a variant
protein.
Length = 1065
Score = 56.0 bits (129), Expect = 1e-07
Identities = 53/227 (23%), Positives = 111/227 (48%), Gaps = 14/227 (6%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR-ELQKKLAQVEEDLILNK 61
AI QAM+ K + T + + + EK+ + + E++ Q + + +
Sbjct: 370 AIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHA 429
Query: 62 NKLEQAN----KDLEEKEKQLTATEAEV-AALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
++E K ++EKE L A +++ A ++ + ++E+ L K +E ++K EA
Sbjct: 430 KEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAE-IKKEKFAEA 488
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK---SDEVSRKLAFVE 173
+ A R + N+ Q EE+ + L++ L++ R D + K DE +L +
Sbjct: 489 SEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAK 548
Query: 174 DELE--VAEDRVKSGD--AKISELEEELKVVGNSLKSLEVSEEKANQ 216
++LE +AE SGD ++++++ +EL++ ++ L++ KAN+
Sbjct: 549 EKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANE 595
Score = 55.6 bits (128), Expect = 2e-07
Identities = 44/231 (19%), Positives = 109/231 (47%), Gaps = 12/231 (5%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANL--RAEKVN--EEVRELQKKLAQVEED 56
M+A++ K+ + EK+N+++ + +A D +L + +N +E ++K A+ E+
Sbjct: 432 MEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKKEKFAEASEE 491
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG---TAQQKL 113
+ + +++ L +KE+Q +++ L + +E + +ER A++KL
Sbjct: 492 AVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKL 551
Query: 114 ----LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
E + + +N+ + + + E +++L +L +A A ++++ K
Sbjct: 552 ENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKA 611
Query: 170 AFVEDE-LEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ E + E+ K + K+S+LE++++ N + L+ E+A +
Sbjct: 612 EQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETK 662
Score = 48.4 bits (110), Expect = 3e-05
Identities = 53/250 (21%), Positives = 103/250 (41%), Gaps = 21/250 (8%)
Query: 12 KLEKDNAMDKADTCEQQARDANL--RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
KL ++ A +A E+ R+ L EK+ ++ E+ K L ++L +
Sbjct: 522 KLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKER 581
Query: 70 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV 129
D+EE + +LT + L + ++ + E+S+ Q++A ++ K
Sbjct: 582 DVEELQLKLTKANENASFLQKSIEDMTVKAEQSQ-------------QEAAKKHEEEKKE 628
Query: 130 LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK-LAFVEDELEVAEDRVKSGDA 188
LE + E++M+ NQ +E + E A ++ + L ++ L ED++K
Sbjct: 629 LERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGARE 688
Query: 189 KISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKK 248
+ S L +EL+ + + + KA Q E+ +T K
Sbjct: 689 ENSGLLQELEELRK-----QAEKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAK 743
Query: 249 LQKEVDRLED 258
LQ E+D L++
Sbjct: 744 LQNELDTLKE 753
Score = 47.6 bits (108), Expect = 5e-05
Identities = 45/214 (21%), Positives = 88/214 (41%), Gaps = 7/214 (3%)
Query: 12 KLEKDNA--MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 69
KLE D A M + Q N +V ELQ KL + E+ + +E
Sbjct: 550 KLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTV 609
Query: 70 DLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
E+ +++ E E L RK+ +E+ +E S + + + A +++ + +
Sbjct: 610 KAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERA--TSETKTKHEE 667
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADG--KSDEVSRKLAFVEDELEVAEDRVKSG 186
+L+N + + D+L +E L ++ + K E ++ ED +++ E K
Sbjct: 668 ILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAKAAQTAEDAMQIMEQMTKEK 727
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
++ LE+ + L+ +E + VEE
Sbjct: 728 TETLASLEDTKQTNAKLQNELDTLKENNLKNVEE 761
Score = 44.4 bits (100), Expect = 5e-04
Identities = 42/224 (18%), Positives = 105/224 (46%), Gaps = 16/224 (7%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAE--------KVNEEVRELQKKLAQVEED 56
++ ++ ++L+ A + A ++ D ++AE K EE +EL++KL+ +E+
Sbjct: 580 ERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKK 639
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAA-LNRKVQQIEEDLEKSEERSGTAQQKLLE 115
+ + N+ ++ E + E+ L + + E+ L+ + E + Q+L E
Sbjct: 640 METSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEE 699
Query: 116 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL-AFVED 174
++ A++ K + A+ + M+Q+T + E ED + ++ +L E+
Sbjct: 700 LRKQAEK----AKAAQT-AEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKEN 754
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRV 218
L+ E+ KS + E ++++ +++L+ + + +Q++
Sbjct: 755 NLKNVEELNKSKELLTVE-NQKMEEFRKEIETLKQAAAQKSQQL 797
Score = 41.9 bits (94), Expect = 0.002
Identities = 42/211 (19%), Positives = 94/211 (44%), Gaps = 7/211 (3%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
M+ M EK + + +Q + + E + ++L + +E L + K+E+
Sbjct: 720 MEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEF 779
Query: 68 NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMC 127
K++E ++ +++AL + ++ E+L +S + T+ QKL E + +
Sbjct: 780 RKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEV-TSHQKLEEERSVLNNQLLEM 838
Query: 128 KVLENRAQQD-EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
K E++ +D +E L + L + D + +++ ++ + E A KS
Sbjct: 839 KKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASA----KSL 894
Query: 187 DAKISELEEELKVVGNSLKSLEVSEEKANQR 217
+ + LE + + +K+LE+ + K N+R
Sbjct: 895 HSVVQTLESDKVKLELKVKNLEL-QLKENKR 924
Score = 41.1 bits (92), Expect = 0.004
Identities = 36/178 (20%), Positives = 82/178 (46%), Gaps = 8/178 (4%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
Q A DA E++ +E E L ++ +N+L+ ++ + ++L ++ +
Sbjct: 711 QTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLT 770
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS----ADENNRMCKVLENRAQQDEERMD 142
N+K+++ +++E ++ + Q+L Q+ A+E R + + + +EER
Sbjct: 771 VENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEER-S 829
Query: 143 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVV 200
L NQL E + +DE + A ++ + + + DA++ +L E+ V+
Sbjct: 830 VLNNQLLEMKKRESKFIKDADE---EKASLQKSISITSALLTEKDAELEKLRNEVTVL 884
Score = 37.5 bits (83), Expect = 0.053
Identities = 46/234 (19%), Positives = 107/234 (45%), Gaps = 32/234 (13%)
Query: 15 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED----LILNKNKLEQA--- 67
K++ + +T +++ + EK+++E L+ KL ++ + L K+KLE A
Sbjct: 314 KEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIAS 373
Query: 68 -NKDLEEKE----KQLTATEAEVAALNRKVQQIE-------EDLEKSEERSGTAQQKLLE 115
+ +EE + K L AE A L +++++ E+L+ ++ A K +E
Sbjct: 374 HQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEME 433
Query: 116 AQQSA-----DENNRMCKVLENRAQQDEER----MDQLTNQLKEARLLAEDADGKSDEVS 166
A ++ E + + ++ + E++ M+ N+L+EA + E K E S
Sbjct: 434 ALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKKE----KFAEAS 489
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+ V+ ++ +++ + + + L +L+ + +L +E + ++R E+
Sbjct: 490 EEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQ 543
Score = 36.3 bits (80), Expect = 0.12
Identities = 37/159 (23%), Positives = 69/159 (43%), Gaps = 14/159 (8%)
Query: 76 KQLTATEAEVAALNRKVQQIEE-----DLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 130
++++ T A AL K Q IE+ DLE++E T+ +E + + + VL
Sbjct: 96 RKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVL 155
Query: 131 ENRAQQDE-----ERMD----QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 181
E A+ D+ E D +L NQL+E + ED + +E S +E + ++
Sbjct: 156 ELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHA 215
Query: 182 RVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
R+K + + + + + L+ V+ R+ E
Sbjct: 216 RIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIME 254
Score = 34.3 bits (75), Expect = 0.49
Identities = 42/197 (21%), Positives = 89/197 (45%), Gaps = 13/197 (6%)
Query: 35 RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 94
R E +E++ L ++ ++ K+KLE ANK E + ++++ QQ
Sbjct: 320 REETHQKEIKALYTATEKLSKENESLKSKLEHANK---ENSDVIALWKSKLETAIASHQQ 376
Query: 95 IEEDLEKSEERS-GTAQQKLLEAQQSADENNRMCK-VLEN-RAQQDEERMDQLTN-QLKE 150
E+L+ S + GT + E + ++ + +EN + QQD ER +
Sbjct: 377 AMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALR 436
Query: 151 ARLL--AEDADGKSDEVSRKLAFVED----ELEVAEDRVKSGDAKISELEEELKVVGNSL 204
A+L+ ++ + + + KL ED E+E ++++ + K + E + +
Sbjct: 437 AKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKKEKFAEASEEAVSVQ 496
Query: 205 KSLEVSEEKANQRVEEF 221
+S++ + K +Q+ E+F
Sbjct: 497 RSMQETVNKLHQKEEQF 513
Score = 31.5 bits (68), Expect = 3.5
Identities = 30/168 (17%), Positives = 86/168 (51%), Gaps = 5/168 (2%)
Query: 12 KLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDL 71
++E++ A+ + D +Q + + +++ V ++ ++ L K K+E +
Sbjct: 138 EIEQELALAR-DGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRV 196
Query: 72 EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ-QSADENNRMCKVL 130
EE+ E + + +++++E+ L + ++ Q++L + + + E +R+ ++
Sbjct: 197 EEESITKGDLETQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELE 256
Query: 131 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
++ A + +E + +L +L E+ A D D S + ++++ ++++LEV
Sbjct: 257 KDLALRVQE-VAELRRRL-ESNKPAGDVD-MSLSLLQEISSLQEKLEV 301
>AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant 2
protein.
Length = 1715
Score = 56.0 bits (129), Expect = 1e-07
Identities = 44/180 (24%), Positives = 81/180 (45%), Gaps = 8/180 (4%)
Query: 48 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI-------EEDLE 100
K A + ++ KN+LE++ K A E E+ L+ ++ I EE L
Sbjct: 1352 KNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1411
Query: 101 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+ + Q +L E Q+ +E + K +A +D +++ L QL+EA ++
Sbjct: 1412 RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQE 1471
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
K + ++ F+E + V + V +AKI ELE L+ +K LE + + +E+
Sbjct: 1472 KLQALQSQVEFLEQSM-VDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEK 1530
Score = 55.6 bits (128), Expect = 2e-07
Identities = 60/290 (20%), Positives = 136/290 (46%), Gaps = 24/290 (8%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL--ILN 60
A K +AM++E ++ + D + + ++ E E+Q +L + +ED+ ++
Sbjct: 1377 AAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMK 1436
Query: 61 KNK--LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE-----------ERSG 107
K+K + QA++DL Q+ +A++ N++ Q+++E L+ + ++S
Sbjct: 1437 KHKAAVAQASRDLA----QINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSL 1492
Query: 108 TAQQ--KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE- 164
++Q K+ E + + K LE+ A + +E M++LT + ++ R+ AE+ + + ++
Sbjct: 1493 VSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-RDQRIAAENREKEQNKR 1551
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXX 224
+ R+L ++E+ + K ELE +L+ + + +SL+ + A +R+ +
Sbjct: 1552 LQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAA 1611
Query: 225 XXXXXXXXXXXXXXXXXXXKTV-KKLQKEVDRLEDELGINKDRYKSLADE 273
V +L+ VD ++ L NK K+ +D+
Sbjct: 1612 IEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSKAASDD 1661
Score = 54.0 bits (124), Expect = 6e-07
Identities = 51/218 (23%), Positives = 106/218 (48%), Gaps = 14/218 (6%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR--ELQKKLAQVEEDLILN---- 60
++Q KL + + E++ R + + +EE + +LQ++ Q E+D++L
Sbjct: 1114 ELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS 1173
Query: 61 -KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
K +LE+ + D+ +++ + EAE+ ++ + + E L K +++ + K+ + ++
Sbjct: 1174 LKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEE 1233
Query: 120 ADENNRMCKVLEN---RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
DE ++LE R + + ERM Q ++ E+R E+ + +KL +E +L
Sbjct: 1234 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESR--DEEVEEARQSCQKKLKQMEVQL 1291
Query: 177 EVA-EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E ED+ K K ELE +L + + + + EK
Sbjct: 1292 EEEYEDKQKVLREK-RELEGKLATLSDQVNRRDFESEK 1328
Score = 53.2 bits (122), Expect = 1e-06
Identities = 56/228 (24%), Positives = 105/228 (46%), Gaps = 11/228 (4%)
Query: 2 DAIKKKMQAMKL--EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
+A ++K+Q KL EKD + +A + +QQ + ++ ++V L+ +L +
Sbjct: 1149 EAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESK 1208
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLEA 116
++ L + K L + E ++ E E+ +Q +E+ LE ER K +E+
Sbjct: 1209 DEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMES 1268
Query: 117 Q-QSADENNRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
+ + +E + C K L+ Q EE + L+E R L SD+V+R+ E
Sbjct: 1269 RDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRR--DFES 1326
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKS-LEVSEEKANQRVEEF 221
E + +D +K A +++ + L + NS S E+++ K EF
Sbjct: 1327 EKRLRKD-LKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEF 1373
Score = 46.0 bits (104), Expect = 2e-04
Identities = 50/226 (22%), Positives = 102/226 (45%), Gaps = 20/226 (8%)
Query: 2 DAIKKKMQAMKLEKDNA-MDKADTCEQQARDAN------LRAEKVNEEVRELQKKLAQVE 54
DA+KK+M+ M++E A + +A + D + L+ E+ EV +K+L Q
Sbjct: 1010 DALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEF 1069
Query: 55 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
ED K ++EQ NK + E++L +A+ R +QQ++ +K + + Q L
Sbjct: 1070 ED----KLEVEQQNK--RQLERRLGDLQADSEESQRALQQLK---KKCQRLTAELQDTKL 1120
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
+ N+ LE + ++ + + Q + + +L E + D + + ++
Sbjct: 1121 HLEGQQVRNHE----LEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ 1176
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+LE + + K+ LE EL+ + + E S K +++ +
Sbjct: 1177 QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRD 1222
Score = 45.2 bits (102), Expect = 3e-04
Identities = 42/198 (21%), Positives = 88/198 (44%), Gaps = 12/198 (6%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
QQ + L E+ N+ R+L+++L ++ D ++ L+Q K + +L T+ +
Sbjct: 1066 QQEFEDKLEVEQQNK--RQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLE 1123
Query: 87 ALNRKVQQIEE-----DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
+ ++E+ D E S+ ++KL + +++ + + + Q +E+ M
Sbjct: 1124 GQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDM 1183
Query: 142 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 201
D K L AE D S E E L + +++ +AK+ + EEEL
Sbjct: 1184 DIAGFTQKVVSLEAELQDISSQESKD-----EASLAKVKKQLRDLEAKVKDQEEELDEQA 1238
Query: 202 NSLKSLEVSEEKANQRVE 219
+++ LE ++ + +E
Sbjct: 1239 GTIQMLEQAKLRLEMEME 1256
Score = 41.9 bits (94), Expect = 0.002
Identities = 36/191 (18%), Positives = 85/191 (44%), Gaps = 4/191 (2%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
++ KL + M++ + +++ R E+V E + QKKL Q+E L ++
Sbjct: 1244 LEQAKLRLEMEMERMR--QTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKV 1301
Query: 68 NKDLEEKEKQLTATEAEVAALN-RKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
++ E E +L +V + +++ +DL++++ AQ L + SA +
Sbjct: 1302 LREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREI 1361
Query: 127 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
+ L+N+ ++ E K + ED + D++++ +E++L +
Sbjct: 1362 AQ-LKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEI 1420
Query: 187 DAKISELEEEL 197
++ E +E++
Sbjct: 1421 QNRLEEDQEDM 1431
Score = 38.3 bits (85), Expect = 0.030
Identities = 55/239 (23%), Positives = 111/239 (46%), Gaps = 29/239 (12%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRA--EKVNEEVRELQKKLAQVEEDLI 58
+D KK++Q + E +++ + + + R +L+A E+ +++L+KK ++ +L
Sbjct: 1058 VDFTKKRLQ-QEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ 1116
Query: 59 LNKNKLE---QANKDLEEKEKQLTA------TEAEVAALNRKVQQIEEDLEKSEERSGTA 109
K LE N +LE+K+++ + EA+ L R+ Q E+D+ +E S
Sbjct: 1117 DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS--L 1174
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQ-------QDEERMDQLTNQLKEARLLAEDADGKS 162
+Q+L E + LE Q +DE + ++ QL++ +D + +
Sbjct: 1175 KQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEEL 1234
Query: 163 DEVSRKLAFVED---ELEVAEDRV-----KSGDAKISELEEELKVVGNSLKSLEVSEEK 213
DE + + +E LE+ +R+ K +++ E+EE + LK +EV E+
Sbjct: 1235 DEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1293
Score = 33.1 bits (72), Expect = 1.1
Identities = 38/220 (17%), Positives = 98/220 (44%), Gaps = 9/220 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQVEEDLILNKN 62
++ K++ + E++ +D E +R + L +E +E E +L E L
Sbjct: 942 LRSKLEKAEKERNELRLNSDRLE--SRISELTSELTDERNTGESASQLLDAETAERLRAE 999
Query: 63 K-LEQANKDLEEKEKQLTATEAEVAALNR-KVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K +++ + +KQ+ E EV + +I +++ ++ G + K A +
Sbjct: 1000 KEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVD-DDDAGGEWRLKYERAVREV 1058
Query: 121 D-ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
D R+ + E++ + +++ QL +L + + +E++ ++ +K + EL+
Sbjct: 1059 DFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDT 1118
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ ++ + ELE++ + + L + EE ++++
Sbjct: 1119 KLHLEGQQVRNHELEKKQRRFDSELS--QAHEEAQREKLQ 1156
>AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant 1
protein.
Length = 2046
Score = 56.0 bits (129), Expect = 1e-07
Identities = 44/180 (24%), Positives = 81/180 (45%), Gaps = 8/180 (4%)
Query: 48 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI-------EEDLE 100
K A + ++ KN+LE++ K A E E+ L+ ++ I EE L
Sbjct: 1668 KNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1727
Query: 101 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 160
+ + Q +L E Q+ +E + K +A +D +++ L QL+EA ++
Sbjct: 1728 RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQE 1787
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
K + ++ F+E + V + V +AKI ELE L+ +K LE + + +E+
Sbjct: 1788 KLQALQSQVEFLEQSM-VDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEK 1846
Score = 54.0 bits (124), Expect = 6e-07
Identities = 51/218 (23%), Positives = 106/218 (48%), Gaps = 14/218 (6%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR--ELQKKLAQVEEDLILN---- 60
++Q KL + + E++ R + + +EE + +LQ++ Q E+D++L
Sbjct: 1430 ELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS 1489
Query: 61 -KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
K +LE+ + D+ +++ + EAE+ ++ + + E L K +++ + K+ + ++
Sbjct: 1490 LKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEE 1549
Query: 120 ADENNRMCKVLEN---RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
DE ++LE R + + ERM Q ++ E+R E+ + +KL +E +L
Sbjct: 1550 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESR--DEEVEEARQSCQKKLKQMEVQL 1607
Query: 177 EVA-EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
E ED+ K K ELE +L + + + + EK
Sbjct: 1608 EEEYEDKQKVLREK-RELEGKLATLSDQVNRRDFESEK 1644
Score = 53.2 bits (122), Expect = 1e-06
Identities = 56/228 (24%), Positives = 105/228 (46%), Gaps = 11/228 (4%)
Query: 2 DAIKKKMQAMKL--EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
+A ++K+Q KL EKD + +A + +QQ + ++ ++V L+ +L +
Sbjct: 1465 EAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESK 1524
Query: 60 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLEA 116
++ L + K L + E ++ E E+ +Q +E+ LE ER K +E+
Sbjct: 1525 DEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMES 1584
Query: 117 Q-QSADENNRMC-KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
+ + +E + C K L+ Q EE + L+E R L SD+V+R+ E
Sbjct: 1585 RDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRR--DFES 1642
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKS-LEVSEEKANQRVEEF 221
E + +D +K A +++ + L + NS S E+++ K EF
Sbjct: 1643 EKRLRKD-LKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEF 1689
Score = 52.8 bits (121), Expect = 1e-06
Identities = 57/281 (20%), Positives = 132/281 (46%), Gaps = 24/281 (8%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL--ILN 60
A K +AM++E ++ + D + + ++ E E+Q +L + +ED+ ++
Sbjct: 1693 AAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMK 1752
Query: 61 KNK--LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE-----------ERSG 107
K+K + QA++DL Q+ +A++ N++ Q+++E L+ + ++S
Sbjct: 1753 KHKAAVAQASRDLA----QINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSL 1808
Query: 108 TAQQ--KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE- 164
++Q K+ E + + K LE+ A + +E M++LT + ++ R+ AE+ + + ++
Sbjct: 1809 VSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-RDQRIAAENREKEQNKR 1867
Query: 165 VSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXX 224
+ R+L ++E+ + K ELE +L+ + + +SL+ + A +R+ +
Sbjct: 1868 LQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDL-QA 1926
Query: 225 XXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKD 265
V K QK ++LE + ++ +
Sbjct: 1927 AIEDEMESDENEDLINSLQDMVTKYQKRKNKLEGDSDVDSE 1967
Score = 46.0 bits (104), Expect = 2e-04
Identities = 50/226 (22%), Positives = 102/226 (45%), Gaps = 20/226 (8%)
Query: 2 DAIKKKMQAMKLEKDNA-MDKADTCEQQARDAN------LRAEKVNEEVRELQKKLAQVE 54
DA+KK+M+ M++E A + +A + D + L+ E+ EV +K+L Q
Sbjct: 1326 DALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEF 1385
Query: 55 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 114
ED K ++EQ NK + E++L +A+ R +QQ++ +K + + Q L
Sbjct: 1386 ED----KLEVEQQNK--RQLERRLGDLQADSEESQRALQQLK---KKCQRLTAELQDTKL 1436
Query: 115 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 174
+ N+ LE + ++ + + Q + + +L E + D + + ++
Sbjct: 1437 HLEGQQVRNHE----LEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ 1492
Query: 175 ELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
+LE + + K+ LE EL+ + + E S K +++ +
Sbjct: 1493 QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRD 1538
Score = 45.2 bits (102), Expect = 3e-04
Identities = 42/198 (21%), Positives = 88/198 (44%), Gaps = 12/198 (6%)
Query: 27 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
QQ + L E+ N+ R+L+++L ++ D ++ L+Q K + +L T+ +
Sbjct: 1382 QQEFEDKLEVEQQNK--RQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLE 1439
Query: 87 ALNRKVQQIEE-----DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
+ ++E+ D E S+ ++KL + +++ + + + Q +E+ M
Sbjct: 1440 GQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDM 1499
Query: 142 DQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVG 201
D K L AE D S E E L + +++ +AK+ + EEEL
Sbjct: 1500 DIAGFTQKVVSLEAELQDISSQESKD-----EASLAKVKKQLRDLEAKVKDQEEELDEQA 1554
Query: 202 NSLKSLEVSEEKANQRVE 219
+++ LE ++ + +E
Sbjct: 1555 GTIQMLEQAKLRLEMEME 1572
Score = 41.9 bits (94), Expect = 0.002
Identities = 36/191 (18%), Positives = 85/191 (44%), Gaps = 4/191 (2%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
++ KL + M++ + +++ R E+V E + QKKL Q+E L ++
Sbjct: 1560 LEQAKLRLEMEMERMR--QTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKV 1617
Query: 68 NKDLEEKEKQLTATEAEVAALN-RKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
++ E E +L +V + +++ +DL++++ AQ L + SA +
Sbjct: 1618 LREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREI 1677
Query: 127 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 186
+ L+N+ ++ E K + ED + D++++ +E++L +
Sbjct: 1678 AQ-LKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEI 1736
Query: 187 DAKISELEEEL 197
++ E +E++
Sbjct: 1737 QNRLEEDQEDM 1747
Score = 39.5 bits (88), Expect = 0.013
Identities = 33/141 (23%), Positives = 67/141 (47%), Gaps = 9/141 (6%)
Query: 28 QARDANLRAE-KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 86
+ RD + AE + E+ + LQ++L +E++ E A K+ E K+ E ++
Sbjct: 1849 EERDQRIAAENREKEQNKRLQRQLRDTKEEMG------ELARKEAEASRKK-HELEMDLE 1901
Query: 87 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 146
+L Q ++ DL+ + +R G Q + E + +DEN + L++ + ++R ++L
Sbjct: 1902 SLEAANQSLQADLKLAFKRIGDLQAAI-EDEMESDENEDLINSLQDMVTKYQKRKNKLEG 1960
Query: 147 QLKEARLLAEDADGKSDEVSR 167
L + DG +S+
Sbjct: 1961 DSDVDSELEDRVDGVKSWLSK 1981
Score = 38.3 bits (85), Expect = 0.030
Identities = 55/239 (23%), Positives = 111/239 (46%), Gaps = 29/239 (12%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRA--EKVNEEVRELQKKLAQVEEDLI 58
+D KK++Q + E +++ + + + R +L+A E+ +++L+KK ++ +L
Sbjct: 1374 VDFTKKRLQ-QEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ 1432
Query: 59 LNKNKLE---QANKDLEEKEKQLTA------TEAEVAALNRKVQQIEEDLEKSEERSGTA 109
K LE N +LE+K+++ + EA+ L R+ Q E+D+ +E S
Sbjct: 1433 DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS--L 1490
Query: 110 QQKLLEAQQSADENNRMCKVLENRAQ-------QDEERMDQLTNQLKEARLLAEDADGKS 162
+Q+L E + LE Q +DE + ++ QL++ +D + +
Sbjct: 1491 KQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEEL 1550
Query: 163 DEVSRKLAFVED---ELEVAEDRV-----KSGDAKISELEEELKVVGNSLKSLEVSEEK 213
DE + + +E LE+ +R+ K +++ E+EE + LK +EV E+
Sbjct: 1551 DEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1609
Score = 33.1 bits (72), Expect = 1.1
Identities = 38/220 (17%), Positives = 98/220 (44%), Gaps = 9/220 (4%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQVEEDLILNKN 62
++ K++ + E++ +D E +R + L +E +E E +L E L
Sbjct: 1258 LRSKLEKAEKERNELRLNSDRLE--SRISELTSELTDERNTGESASQLLDAETAERLRAE 1315
Query: 63 K-LEQANKDLEEKEKQLTATEAEVAALNR-KVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K +++ + +KQ+ E EV + +I +++ ++ G + K A +
Sbjct: 1316 KEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVD-DDDAGGEWRLKYERAVREV 1374
Query: 121 D-ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 179
D R+ + E++ + +++ QL +L + + +E++ ++ +K + EL+
Sbjct: 1375 DFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDT 1434
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ ++ + ELE++ + + L + EE ++++
Sbjct: 1435 KLHLEGQQVRNHELEKKQRRFDSELS--QAHEEAQREKLQ 1472
>Z75311-1|CAA99729.1| 1318|Homo sapiens RAD50 homologue hsRAD50
protein.
Length = 1318
Score = 55.6 bits (128), Expect = 2e-07
Identities = 42/190 (22%), Positives = 90/190 (47%), Gaps = 8/190 (4%)
Query: 28 QARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAA 87
Q D + ++VN+E +E Q KL V + LN+ ++ + ++ + ++E
Sbjct: 823 QGIDLDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQ 882
Query: 88 LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQ 147
++ +Q+ ++ E++ E S Q E + + ++ + + LE Q+ EE L N+
Sbjct: 883 ISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEKEE----LINK 938
Query: 148 LKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG-DAKISELEEELKVVGNSLKS 206
+ +A+D K +++ K+ + ++ E+ ++ G D + + E EL V L
Sbjct: 939 KNTSNKIAQD---KLNDIKEKVKNIHGYMKDIENHIQDGKDDYMKQKETELNKVIAQLSE 995
Query: 207 LEVSEEKANQ 216
E +EK N+
Sbjct: 996 CEKHKEKINE 1005
Score = 52.8 bits (121), Expect = 1e-06
Identities = 42/191 (21%), Positives = 94/191 (49%), Gaps = 14/191 (7%)
Query: 40 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL------NRKVQ 93
++E+ + + +LA++ ++L ++ N +LE KE+QL++ E ++ + +
Sbjct: 590 SKEINQTRDRLAKLNKELASSEQNKNHINNELERKEEQLSSYEDKLFDVCGSQDFESDLD 649
Query: 94 QIEEDLEKS-EERSGTAQQKLLEAQ---QSADENNRMCKVLENRAQQDEERMDQLTNQLK 149
+++E++EKS ++R+ A + +Q Q DEN C V + Q + E + +++
Sbjct: 650 RLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEAISDLQS 709
Query: 150 EARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEV 209
+ RL + E+ +K ++ L +A R D K E+E+ + N L+++
Sbjct: 710 KLRLAPDKLKSTESELKKKEKRRDEMLGLAPMRQSIIDLK----EKEIPELRNKLQNVNR 765
Query: 210 SEEKANQRVEE 220
++ +EE
Sbjct: 766 DIQRLKNDIEE 776
Score = 45.2 bits (102), Expect = 3e-04
Identities = 47/193 (24%), Positives = 96/193 (49%), Gaps = 16/193 (8%)
Query: 34 LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 93
L +K+ EL+KK + D +L + Q+ DL KEK++ ++ +NR +Q
Sbjct: 713 LAPDKLKSTESELKKK--EKRRDEMLGLAPMRQSIIDL--KEKEIPELRNKLQNVNRDIQ 768
Query: 94 QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 153
+++ D+E+ E GT ++ ++SA ++E R Q + + +++ Q + A+L
Sbjct: 769 RLKNDIEEQETLLGT----IMPEEESAKVCLTDVTIME-RFQMELKDVERKIAQ-QAAKL 822
Query: 154 LAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE---LKVVGNSLKS--LE 208
D D +V+++ + +L+ +++ I + +E+ LK N LKS L+
Sbjct: 823 QGIDLDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQ 882
Query: 209 VSEE-KANQRVEE 220
+S + Q++EE
Sbjct: 883 ISTNLQRRQQLEE 895
Score = 40.7 bits (91), Expect = 0.006
Identities = 44/235 (18%), Positives = 103/235 (43%), Gaps = 20/235 (8%)
Query: 35 RAEKVNEEVRELQKKLAQVEEDLI---LNKNKLEQ----ANKDLEEKEKQLTATEAEVAA 87
+A+K +E++R+++ + + L+ NK +LE +K++ + +L E+A+
Sbjct: 551 KADK-DEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELAS 609
Query: 88 LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER--MDQLT 145
+ I +LE+ EE+ + + KL + S D + + ++ E + ++R + T
Sbjct: 610 SEQNKNHINNELERKEEQLSSYEDKLFDVCGSQDFESDLDRLKEEIEKSSKQRAMLAGAT 669
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
+ D + V +++ E EL+ A IS+L+ +L++ + LK
Sbjct: 670 AVYSQFITQLTDENQSCCPVCQRVFQTEAELQEA----------ISDLQSKLRLAPDKLK 719
Query: 206 SLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
S E +K +R +E ++ + +++ RL++++
Sbjct: 720 STESELKKKEKRRDEMLGLAPMRQSIIDLKEKEIPELRNKLQNVNRDIQRLKNDI 774
Score = 34.3 bits (75), Expect = 0.49
Identities = 46/284 (16%), Positives = 113/284 (39%), Gaps = 22/284 (7%)
Query: 18 AMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQ 77
A DK + E + + R +++ Q + E+++ +NKL+ N+D++ +
Sbjct: 714 APDKLKSTESELKKKEKRRDEMLGLAPMRQSIIDLKEKEIPELRNKLQNVNRDIQRLKND 773
Query: 78 LTATEAEVAALNRKVQQIEEDL------EKSEERSGTAQQKLLE--AQQSADENNRMCKV 129
+ E + + + + + L E+ + ++K+ + A+ + +R +
Sbjct: 774 IEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGIDLDRTVQQ 833
Query: 130 LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV-SRKLAFVEDELEVA--------- 179
+ Q+ + ++D ++++++ R L +D + + S ++L+++
Sbjct: 834 VNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQRRQQL 893
Query: 180 EDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXX 239
E++ ++ L E+K + LE + EK Q EE
Sbjct: 894 EEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKLNDI 953
Query: 240 XXXXKTVKKLQKEVDRLEDELGINKDRY-KSLADEMDSTFAELA 282
K + K++ E+ + KD Y K E++ A+L+
Sbjct: 954 KEKVKNIHGYMKDI---ENHIQDGKDDYMKQKETELNKVIAQLS 994
Score = 33.9 bits (74), Expect = 0.65
Identities = 24/113 (21%), Positives = 55/113 (48%), Gaps = 4/113 (3%)
Query: 38 KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 97
K E +R++++ Q E+ + L+Q + E Q+T+ EA++ + V+ E
Sbjct: 193 KALETLRQVRQTQGQKVEEYQMELKYLKQYKEKACEIRDQITSKEAQLTSSKEIVKSYEN 252
Query: 98 DLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE 150
+L+ + R + L + + +E K L++R +Q E+ +L ++++
Sbjct: 253 ELDPLKNRLKEIEHNLSKIMKLDNE----IKALDSRKKQMEKDNSELEEKMEK 301
Score = 33.9 bits (74), Expect = 0.65
Identities = 31/171 (18%), Positives = 85/171 (49%), Gaps = 11/171 (6%)
Query: 35 RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 94
+A ++ +++ + +L +E + +N+L+ L+E E L+ ++ L+ +++
Sbjct: 225 KACEIRDQITSKEAQLTSSKEIVKSYENELDPLKNRLKEIEHNLS----KIMKLDNEIKA 280
Query: 95 IEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 154
++ ++ E+ + ++K+ + Q DE ++ + N + E+ +L + +E L
Sbjct: 281 LDSRKKQMEKDNSELEEKMEKVFQGTDE--QLNDLYHNHQRTVREKERKLVDCHRELEKL 338
Query: 155 AEDADGKSDEVSRKLAFVEDELEVAEDR----VKSGDAKISELEEELKVVG 201
+++ + E S +L + L++ DR +++ D+ I L +L++ G
Sbjct: 339 NKESRLLNQEKS-ELLVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDG 388
Score = 30.3 bits (65), Expect = 8.0
Identities = 36/216 (16%), Positives = 105/216 (48%), Gaps = 24/216 (11%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
++++ KL+ + + E+Q + + + + E+++ +++++ +E L K +Q
Sbjct: 875 ELKSEKLQISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTL----EKFQQ 930
Query: 67 ANKDL-EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
++L +K + ++ + KV+ I ++ E + + +Q E N+
Sbjct: 931 EKEELINKKNTSNKIAQDKLNDIKEKVKNIHGYMKDIENHIQDGKDDYM--KQKETELNK 988
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
+ L + ++ +E++++ + RL+ +D D + ++ + +++D L ++
Sbjct: 989 VIAQL-SECEKHKEKINE------DMRLMRQDID--TQKIQER--WLQDNL-----TLRK 1032
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKA-NQRVEE 220
+ ++ E+EEE K + ++V + K+ +Q++EE
Sbjct: 1033 RNEELKEVEEEGKQHLKEMGQMQVLQMKSEHQKLEE 1068
>D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein.
Length = 1388
Score = 55.6 bits (128), Expect = 2e-07
Identities = 64/274 (23%), Positives = 130/274 (47%), Gaps = 28/274 (10%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDL----ILNKNKLEQANKDLEEKEKQLTAT 81
E+ ++ + KV E R+LQ++ +E++ I +L+ + LE++E + AT
Sbjct: 652 EEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKAT 711
Query: 82 EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE---AQQSAD----ENNRMCKVLENRA 134
+A +A N+ + IEE KSE ++KLLE +Q + E + C +L+
Sbjct: 712 KARLADKNKIYESIEE--AKSEAMK-EMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDL 768
Query: 135 QQDEERMDQLTNQLKEARLLAEDADG---KSDEVSRKLAFVEDELEVAEDRVKSGDAKIS 191
+Q ++++++L LK+ +L ED K ++ ++K +++L++ +V + K+S
Sbjct: 769 KQSQQKINEL---LKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNT--LKMS 823
Query: 192 ELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQK 251
E++LK N L ++++ EK N + + K +
Sbjct: 824 --EKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVR 881
Query: 252 EV-DRLEDELGINKD---RYKSLADEMDSTFAEL 281
E+ + E++ + K+ + + L DE DS A+L
Sbjct: 882 ELKEECEEKTKLGKELQQKKQELQDERDSLAAQL 915
Score = 54.4 bits (125), Expect = 4e-07
Identities = 46/185 (24%), Positives = 88/185 (47%), Gaps = 9/185 (4%)
Query: 40 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQL-TATEAEVAALNRKV---QQI 95
NEE +E+QKKL +EE L N++ QA ++LE+K K + T E L ++ + +
Sbjct: 439 NEESQEIQKKLYTLEEHL---SNEM-QAKEELEQKCKSVNTRLEKTAKELEEEITLRKSV 494
Query: 96 EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
E L + E Q K E Q+ AD + LEN +++++ L + + +++
Sbjct: 495 ESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQIST 554
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
E + ++ A + E + A R++ A+ S+ ++L+ L+ E A
Sbjct: 555 EKVNQLQRQLDETNALLRTESDTAA-RLRKTQAESSKQIQQLESNNRDLQDKNCLLETAK 613
Query: 216 QRVEE 220
++E+
Sbjct: 614 LKLEK 618
Score = 50.0 bits (114), Expect = 9e-06
Identities = 34/162 (20%), Positives = 70/162 (43%), Gaps = 3/162 (1%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRE---LQKKLAQVEEDLILN 60
I+KK+ ++ N M + EQ+ + N R EK +E+ E L+K + L
Sbjct: 445 IQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEITLRKSVESALRQLERE 504
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K L+ N + + K + + ++ EDL+K + S + +K+ + Q+
Sbjct: 505 KALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQL 564
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
DE N + + + A + + + + Q+++ D K+
Sbjct: 565 DETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKN 606
Score = 48.4 bits (110), Expect = 3e-05
Identities = 47/223 (21%), Positives = 101/223 (45%), Gaps = 15/223 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADT----CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
+K+K++ + LE + D +Q+ + + + +NE+VR L K+ Q + L
Sbjct: 746 LKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCL 805
Query: 60 NKNKLE---QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+N L+ Q L+ EKQL + + +++ +L K E + Q K L+
Sbjct: 806 TQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRK-ERQDADGQMKELQD 864
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
Q A++ + + + ++ +E ++ T KE + ++ + D ++ +L +
Sbjct: 865 QLEAEQ--YFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKA 922
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ + + + S+LE+E K+ +K LE+ E A + E
Sbjct: 923 DSEQLARSIAEEQYSDLEKE-KI----MKELEIKEMMARHKQE 960
Score = 46.8 bits (106), Expect = 9e-05
Identities = 59/284 (20%), Positives = 108/284 (38%), Gaps = 16/284 (5%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRA--EKVNEEVRELQKKLA------QVEEDLI 58
K+ LE++ A KA ++ + E +E ++E++KKL Q E+L+
Sbjct: 695 KVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLL 754
Query: 59 LNKNK-LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
L K + DL++ ++++ + LN V+ + +E+ ++ Q L
Sbjct: 755 LEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQT 814
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
Q + K L+ E L Q E R +DADG+ E ++D+LE
Sbjct: 815 QQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKE-------LQDQLE 867
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXX 237
+ ++ EL+EE + K L+ +++ +
Sbjct: 868 AEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQL 927
Query: 238 XXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ L+KE E E+ R+K E D+T A L
Sbjct: 928 ARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASL 971
Score = 31.5 bits (68), Expect = 3.5
Identities = 41/218 (18%), Positives = 89/218 (40%), Gaps = 8/218 (3%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
K + ++ + ++ D+ + +++ +++ + EKVN+ LQ++L + L + +
Sbjct: 525 KKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQ----LQRQLDETNALLRTESDTAAR 580
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
K E KQ+ E+ L K +E K E+ Q L ++ + +
Sbjct: 581 LRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEI 640
Query: 127 CKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
L+ R EE + L E R L E E S + +L+V +
Sbjct: 641 INDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQS 700
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
++ +A+ + L +S+E ++ +A + +E+
Sbjct: 701 LEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEK 738
>BC131590-1|AAI31591.1| 754|Homo sapiens EPS15L1 protein protein.
Length = 754
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/144 (21%), Positives = 68/144 (47%)
Query: 76 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 135
K+L E+A L R+ +E+D+ + EE ++ E Q D + LE + Q
Sbjct: 384 KELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQ 443
Query: 136 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 195
++R+D++ Q + R + D K + ++ ++ ++ +++ E +KS + ++ +
Sbjct: 444 DAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKS 503
Query: 196 ELKVVGNSLKSLEVSEEKANQRVE 219
EL + LE S + ++E
Sbjct: 504 ELNRLQQEETQLEQSIQAGRVQLE 527
Score = 53.2 bits (122), Expect = 1e-06
Identities = 33/179 (18%), Positives = 83/179 (46%), Gaps = 7/179 (3%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+ +++E+ +LQ++ +E+D+ + + Q +++E + L + + L + Q +
Sbjct: 387 DDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQ 446
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA----- 151
+ L++ +++ + L + +Q + +M L+ + Q E + + L A
Sbjct: 447 DRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSELN 506
Query: 152 RLLAEDAD-GKSDEVSR-KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
RL E+ +S + R +L + L+ +D + +K+S+L E + SL+ +
Sbjct: 507 RLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYD 565
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/167 (20%), Positives = 81/167 (48%), Gaps = 12/167 (7%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D +Q ++ +K +A D+ D +QQ K+ + + ++++K + +
Sbjct: 428 LDRETSSLQELEAQKQDAQDRLDEMDQQKA-------KLRDMLSDVRQKCQDETQMISSL 480
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K +++ DL+ +E L ++E+ L ++ Q+E+ ++ + T + L Q
Sbjct: 481 KTQIQSQESDLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEI 540
Query: 121 DE-NNRMCKVLENR--AQQDEERMDQLTNQLKEARL--LAEDADGKS 162
++ +++ ++ E+R A + E+ DQ+ + A L LA ++G S
Sbjct: 541 NQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSEGVS 587
Score = 37.5 bits (83), Expect = 0.053
Identities = 38/195 (19%), Positives = 94/195 (48%), Gaps = 28/195 (14%)
Query: 41 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 100
+E+ ++ +++AQ++ + K LEQ D+ EKE+ + +EV Q+++ DL+
Sbjct: 384 KELDDISQEIAQLQRE----KYSLEQ---DIREKEEAIRQKTSEV-------QELQNDLD 429
Query: 101 KS-------EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL--KEA 151
+ E + AQ +L E Q + M + + Q + + + L Q+ +E+
Sbjct: 430 RETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQES 489
Query: 152 RLLAEDAD---GKSD--EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
L +++ D KS+ + ++ +E ++ ++++ + ++E+ + L
Sbjct: 490 DLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQ 549
Query: 207 LEVSEEKANQRVEEF 221
L S ++A++ +E++
Sbjct: 550 LHESRQEAHRSLEQY 564
Score = 36.3 bits (80), Expect = 0.12
Identities = 31/118 (26%), Positives = 57/118 (48%), Gaps = 4/118 (3%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
EQ R+ + EV+ELQ L + L + + + A L+E ++Q +
Sbjct: 404 EQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDML 463
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQ 143
+ + +K Q E + S + +Q+ L++Q+ D+ NR L NR QQ+E +++Q
Sbjct: 464 SDVRQKCQD-ETQMISSLKTQIQSQESDLKSQE--DDLNRAKSEL-NRLQQEETQLEQ 517
Score = 34.7 bits (76), Expect = 0.37
Identities = 29/161 (18%), Positives = 73/161 (45%), Gaps = 6/161 (3%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE-EDLILNKNKLEQANKDLE 72
EK+ A+ + T E Q +L E + + E QK+ AQ +++ K KL D+
Sbjct: 409 EKEEAI-RQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVR 467
Query: 73 EK----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
+K + +++ + ++ + ++ E+DL +++ QQ+ + +QS +
Sbjct: 468 QKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGRVQLE 527
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
+ + ++ ++Q ++L + ++A ++ + L
Sbjct: 528 TIIKSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYDQVL 568
>BC104912-1|AAI04913.1| 1236|Homo sapiens PPFIA2 protein protein.
Length = 1236
Score = 55.6 bits (128), Expect = 2e-07
Identities = 44/181 (24%), Positives = 82/181 (45%), Gaps = 4/181 (2%)
Query: 41 EEVRELQK-KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 99
+E+ E Q ++AQ++E L +++ + ++ E K L TE R +++
Sbjct: 274 QELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQK 333
Query: 100 EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDE---ERMDQLTNQLKEARLLAE 156
E EER T +++ L AQ+ + + M LEN E +M++ QL+E LAE
Sbjct: 334 EDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAE 393
Query: 157 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
++ + L VE EL + + + +EE ++ + L+ ++A Q
Sbjct: 394 QKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQ 453
Query: 217 R 217
R
Sbjct: 454 R 454
Score = 39.1 bits (87), Expect = 0.017
Identities = 33/203 (16%), Positives = 80/203 (39%), Gaps = 2/203 (0%)
Query: 18 AMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQ 77
++++ E++ AN + E+ +Q+K+A E LE + EK+
Sbjct: 198 SLERVSALEEELAAANQEIVALREQNVHIQRKMASSEGST--ESEHLEGMEPGQKVHEKR 255
Query: 78 LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQD 137
L+ + ++ +++E LEK +++L E + + +
Sbjct: 256 LSNGSIDSTDETSQIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKT 315
Query: 138 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 197
EE + ++EA ED + + + ++ + E D + +++ E L
Sbjct: 316 EEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAIL 375
Query: 198 KVVGNSLKSLEVSEEKANQRVEE 220
+ + + L+ E A Q++++
Sbjct: 376 RQMEEKNRQLQERLELAEQKLQQ 398
Score = 39.1 bits (87), Expect = 0.017
Identities = 48/264 (18%), Positives = 103/264 (39%), Gaps = 13/264 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M +K+++ A+ +A+T + K ++RE + +EE +
Sbjct: 284 MAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTL 343
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ + A ++ E E+A ++Q+EE + +ER A+QKL + + A
Sbjct: 344 EKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKA 403
Query: 121 DENNRMCKVLENR---AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
+ + L R + EER + +++ E+ + + ++ E+ +
Sbjct: 404 ETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNK 463
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXX 237
D V D ++E E L++ LK + E+ N ++E
Sbjct: 464 RLSDTV---DRLLTESNERLQL---HLKERMAALEEKNVLIQE----SETFRKNLEESLH 513
Query: 238 XXXXXXKTVKKLQKEVDRLEDELG 261
+ ++KL+ E+D+L+ G
Sbjct: 514 DKERLAEEIEKLRSELDQLKMRTG 537
>BC020921-1|AAH20921.1| 560|Homo sapiens ITSN2 protein protein.
Length = 560
Score = 55.6 bits (128), Expect = 2e-07
Identities = 51/207 (24%), Positives = 98/207 (47%), Gaps = 11/207 (5%)
Query: 6 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 65
+KMQ + +K + D + N+ EK + + E Q++ + E K + E
Sbjct: 347 QKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQR--EAERKAQKEKEEWE 404
Query: 66 QANKDLEEKE-KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
+ ++L+E+E K+ E + +Q EE+ K ER A+Q+L ++ E
Sbjct: 405 RKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERI 464
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELE 177
R ++L N+ +++E + +L ++ K L E +GK ++S +L V + ELE
Sbjct: 465 RRQELL-NQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELE 523
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSL 204
V + + +I +L++EL+ N L
Sbjct: 524 VLDKQCDLEIMEIKQLQQELQEYQNKL 550
>AL832636-1|CAD89951.1| 546|Homo sapiens hypothetical protein
protein.
Length = 546
Score = 55.6 bits (128), Expect = 2e-07
Identities = 47/213 (22%), Positives = 103/213 (48%), Gaps = 13/213 (6%)
Query: 8 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 67
+Q + E++ + + D L+ E+ NE +L+++ ++ E L K +EQ
Sbjct: 260 VQRAREEEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQENMELAERL---KKLIEQY 316
Query: 68 NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMC 127
E +K + + ++ K+QQ +E L+++EER + LL + A E+ RMC
Sbjct: 317 ELREEHIDKVFKHKDLQQQLVDAKLQQAQEMLKEAEERHQREKDFLL---KEAVESQRMC 373
Query: 128 KVL---ENRAQQD----EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
+++ E +Q E+ ++ N L ++ + + + +++++K+ +E E +
Sbjct: 374 ELMKQQETHLKQQLALYTEKFEEFQNTLSKSSEVFTTFEQEMEKMTKKIKKLEKETTMYR 433
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEEK 213
R +S + + E+ EE V L+ L+V ++
Sbjct: 434 SRWESSNKALLEMAEEKTVRDKELEGLQVKIQR 466
Score = 38.3 bits (85), Expect = 0.030
Identities = 57/280 (20%), Positives = 106/280 (37%), Gaps = 28/280 (10%)
Query: 5 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 64
+K+M+ ++ ++ + + D + A L K+ RELQ+ ++E+ +
Sbjct: 207 QKQMKLLQKKQSQLVQEKDHLRGEHSKAVLARSKLESLCRELQRHNRSLKEEGV------ 260
Query: 65 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 124
Q ++ EEK K++T + +V + I+ +E+ ER+ +Q EN
Sbjct: 261 -QRAREEEEKRKEVT-SHFQVT-----LNDIQLQMEQHNERNSKLRQ----------ENM 303
Query: 125 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 184
+ + L+ +Q E R + + K L + D K + L E+ + +D +
Sbjct: 304 ELAERLKKLIEQYELREEHIDKVFKHKDLQQQLVDAKLQQAQEMLKEAEERHQREKDFLL 363
Query: 185 SGDAKISELEEELKVVGNSLK-SLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXX 243
+ + E +K LK L + EK EEF
Sbjct: 364 KEAVESQRMCELMKQQETHLKQQLALYTEK----FEEFQNTLSKSSEVFTTFEQEMEKMT 419
Query: 244 KTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAELAG 283
K +KKL+KE + +A+E EL G
Sbjct: 420 KKIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEG 459
Score = 38.3 bits (85), Expect = 0.030
Identities = 15/57 (26%), Positives = 37/57 (64%)
Query: 41 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 97
+E+ ++ KK+ ++E++ + +++ E +NK L E ++ T + E+ L K+Q++E+
Sbjct: 413 QEMEKMTKKIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEGLQVKIQRLEK 469
>AF273047-1|AAG34907.1| 623|Homo sapiens CTCL tumor antigen se20-7
protein.
Length = 623
Score = 55.6 bits (128), Expect = 2e-07
Identities = 57/255 (22%), Positives = 111/255 (43%), Gaps = 17/255 (6%)
Query: 38 KVNEEVRELQKKLAQVEED--LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI 95
K+ ++R+ + + Q+E+D +++ + K Q ++ LE KE+++ + + + + +++
Sbjct: 6 KLITQLRDAKNLIEQLEQDKGMVIAETK-RQMHETLEMKEEEIAQLRSRIKQMTTQGEEL 64
Query: 96 EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV-----LENRAQQDEERMDQLTNQLKE 150
E EKSE + +K L Q +E R K ++ + EE L +L
Sbjct: 65 REQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSR 124
Query: 151 ARLLAEDADGKSDE--VSRKLAFVEDELEVAEDRV-KSGDAKISELEEELKVVGNSLKS- 206
+ D KS E +++ E EL E + K + E +E++KV +S
Sbjct: 125 VKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSE 184
Query: 207 -LEVSEEKANQR---VEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVD-RLEDELG 261
L++S+EK Q +EE +T + E++ LE L
Sbjct: 185 YLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQ 244
Query: 262 INKDRYKSLADEMDS 276
NK++ K LA +++
Sbjct: 245 ENKNQSKDLAVHLEA 259
Score = 48.4 bits (110), Expect = 3e-05
Identities = 46/201 (22%), Positives = 105/201 (52%), Gaps = 12/201 (5%)
Query: 12 KLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDL 71
+LE+D M A+T Q ++ E++ ++R K++ E+L K K E+A
Sbjct: 20 QLEQDKGMVIAETKRQMHETLEMKEEEI-AQLRSRIKQMTTQGEELREQKEKSERA--AF 76
Query: 72 EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE 131
EE EK L+ + A + +++E ++ E+ T++++ + QQ + +V++
Sbjct: 77 EELEKALSTAQKTEEARRKLKAEMDEQIKTIEK---TSEEERISLQQELSRVKQ--EVVD 131
Query: 132 NRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS 191
+ EE++ +L +L E L ++ + +R+ F +++++VA ++ +S KIS
Sbjct: 132 VMKKSSEEQIAKL-QKLHEKELARKEQELTKKLQTREREF-QEQMKVALEKSQSEYLKIS 189
Query: 192 ELEEELKVVGNSLKSLEVSEE 212
+ +E+ + + +L+ LE+ ++
Sbjct: 190 QEKEQQESL--ALEELELQKK 208
Score = 38.3 bits (85), Expect = 0.030
Identities = 44/199 (22%), Positives = 86/199 (43%), Gaps = 23/199 (11%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+ +K + MK E + MD+ QQ D+ ++ +V+ ++ +K L
Sbjct: 370 LSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS--IQRTEKAL---------- 417
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K+++ Q L+E++K L +A V+ +E D+++SE A KL Q
Sbjct: 418 KDQINQLELLLKERDKHLKEHQAH-------VENLEADIKRSEGELQQASAKLDVFQSYQ 470
Query: 121 DENNRMCKVLENR-AQQDEERMDQLTNQLKEARLLAEDADGKSD---EVSRKLAFVEDEL 176
+ K E + AQ ++ +D T ++ + +AE K D E+ V+D +
Sbjct: 471 SATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLM 530
Query: 177 EVAEDRVKSGDAKISELEE 195
+ E + + K+ L +
Sbjct: 531 QQLEKQNSEMEQKVKSLTQ 549
Score = 36.7 bits (81), Expect = 0.092
Identities = 38/212 (17%), Positives = 96/212 (45%), Gaps = 6/212 (2%)
Query: 4 IKKKMQAMKLEKDNAM-DKADTCEQQARDANLRA-EKVNEEVRELQKKLAQVEEDLILNK 61
++K + + EK+ + DK + + N + EK++ + EL+ +++ E ++ +
Sbjct: 305 MEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSE-VLKAR 363
Query: 62 NKLEQANKDLEEK-EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+KLE+ L+++ +K EA++ QQ + + K E S +K L+ Q
Sbjct: 364 HKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQ--I 421
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 180
++ + K + ++ + ++ L +K + + A K D + ++ + E
Sbjct: 422 NQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYE 481
Query: 181 DRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
+++ K+ +LE E ++ + +E ++
Sbjct: 482 EQLAQLQQKLLDLETERILLTKQVAEVEAQKK 513
Score = 36.3 bits (80), Expect = 0.12
Identities = 34/186 (18%), Positives = 90/186 (48%), Gaps = 2/186 (1%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK-EKQLTATEAEVAALNRKVQQI 95
E ++ E+ E+ K ++EE+L + K++ ++ ++LE K ++Q + +V ++ ++ +
Sbjct: 350 ESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS 409
Query: 96 EEDLEKS-EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 154
+ EK+ +++ + L E + E+ + LE ++ E + Q + +L +
Sbjct: 410 IQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSY 469
Query: 155 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKA 214
++ +LA ++ +L E +++E+E + K V L + ++ +
Sbjct: 470 QSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDL 529
Query: 215 NQRVEE 220
Q++E+
Sbjct: 530 MQQLEK 535
Score = 35.1 bits (77), Expect = 0.28
Identities = 58/290 (20%), Positives = 125/290 (43%), Gaps = 28/290 (9%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED------ 56
++++++ +K E + M K+ EQ A+ L +++ + +EL KKL E +
Sbjct: 117 SLQQELSRVKQEVVDVMKKSSE-EQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMK 175
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV-QQIEEDLEKSEERSGTAQQKLLE 115
+ L K++ E K +EKE+Q + E+ + + + E L ++ + T + ++LE
Sbjct: 176 VALEKSQSEYL-KISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILE 234
Query: 116 AQQSAD----ENNRMCKVLENRAQQDEERMD-QLTNQLKEARLLAEDADGKSDEVSRKLA 170
+ S + EN K L + ++ + + ++T +++ + E + D A
Sbjct: 235 LESSLEKSLQENKNQSKDLAVHLEAEKNKHNMEITVMVEKHKTELESLKHQQD------A 288
Query: 171 FVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXX 230
++L+V + + ++ K+ E E+ K LK E+ + +EE
Sbjct: 289 LWTEKLQVLKQQYQTEMEKLREKCEQEKET--LLKDKEIIFQA---HIEEMNEKTLEKLD 343
Query: 231 XXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAE 280
V K + +LE+EL + KD+ + E+++ E
Sbjct: 344 VKQTELESLSSELSEVLKARH---KLEEELSVLKDQTDKMKQELEAKMDE 390
>AF110265-1|AAF21930.1| 864|Homo sapiens epidermal growth factor
receptor substrate EPS15R protein.
Length = 864
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/144 (21%), Positives = 68/144 (47%)
Query: 76 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 135
K+L E+A L R+ +E+D+ + EE ++ E Q D + LE + Q
Sbjct: 384 KELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQ 443
Query: 136 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 195
++R+D++ Q + R + D K + ++ ++ ++ +++ E +KS + ++ +
Sbjct: 444 DAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKS 503
Query: 196 ELKVVGNSLKSLEVSEEKANQRVE 219
EL + LE S + ++E
Sbjct: 504 ELNRLQQEETQLEQSIQAGRVQLE 527
Score = 53.2 bits (122), Expect = 1e-06
Identities = 33/179 (18%), Positives = 83/179 (46%), Gaps = 7/179 (3%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+ +++E+ +LQ++ +E+D+ + + Q +++E + L + + L + Q +
Sbjct: 387 DDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQ 446
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA----- 151
+ L++ +++ + L + +Q + +M L+ + Q E + + L A
Sbjct: 447 DRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSELN 506
Query: 152 RLLAEDAD-GKSDEVSR-KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
RL E+ +S + R +L + L+ +D + +K+S+L E + SL+ +
Sbjct: 507 RLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYD 565
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/167 (20%), Positives = 81/167 (48%), Gaps = 12/167 (7%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D +Q ++ +K +A D+ D +QQ K+ + + ++++K + +
Sbjct: 428 LDRETSSLQELEAQKQDAQDRLDEMDQQKA-------KLRDMLSDVRQKCQDETQMISSL 480
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K +++ DL+ +E L ++E+ L ++ Q+E+ ++ + T + L Q
Sbjct: 481 KTQIQSQESDLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEI 540
Query: 121 DE-NNRMCKVLENR--AQQDEERMDQLTNQLKEARL--LAEDADGKS 162
++ +++ ++ E+R A + E+ DQ+ + A L LA ++G S
Sbjct: 541 NQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSEGVS 587
Score = 37.5 bits (83), Expect = 0.053
Identities = 38/195 (19%), Positives = 94/195 (48%), Gaps = 28/195 (14%)
Query: 41 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 100
+E+ ++ +++AQ++ + K LEQ D+ EKE+ + +EV Q+++ DL+
Sbjct: 384 KELDDISQEIAQLQRE----KYSLEQ---DIREKEEAIRQKTSEV-------QELQNDLD 429
Query: 101 KS-------EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL--KEA 151
+ E + AQ +L E Q + M + + Q + + + L Q+ +E+
Sbjct: 430 RETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQES 489
Query: 152 RLLAEDAD---GKSD--EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
L +++ D KS+ + ++ +E ++ ++++ + ++E+ + L
Sbjct: 490 DLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQ 549
Query: 207 LEVSEEKANQRVEEF 221
L S ++A++ +E++
Sbjct: 550 LHESRQEAHRSLEQY 564
Score = 36.3 bits (80), Expect = 0.12
Identities = 31/118 (26%), Positives = 57/118 (48%), Gaps = 4/118 (3%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
EQ R+ + EV+ELQ L + L + + + A L+E ++Q +
Sbjct: 404 EQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDML 463
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQ 143
+ + +K Q E + S + +Q+ L++Q+ D+ NR L NR QQ+E +++Q
Sbjct: 464 SDVRQKCQD-ETQMISSLKTQIQSQESDLKSQE--DDLNRAKSEL-NRLQQEETQLEQ 517
Score = 34.7 bits (76), Expect = 0.37
Identities = 29/161 (18%), Positives = 73/161 (45%), Gaps = 6/161 (3%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE-EDLILNKNKLEQANKDLE 72
EK+ A+ + T E Q +L E + + E QK+ AQ +++ K KL D+
Sbjct: 409 EKEEAI-RQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVR 467
Query: 73 EK----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
+K + +++ + ++ + ++ E+DL +++ QQ+ + +QS +
Sbjct: 468 QKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGRVQLE 527
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
+ + ++ ++Q ++L + ++A ++ + L
Sbjct: 528 TIIKSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYDQVL 568
>AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein.
Length = 1337
Score = 55.6 bits (128), Expect = 2e-07
Identities = 64/274 (23%), Positives = 130/274 (47%), Gaps = 28/274 (10%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDL----ILNKNKLEQANKDLEEKEKQLTAT 81
E+ ++ + KV E R+LQ++ +E++ I +L+ + LE++E + AT
Sbjct: 601 EEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKAT 660
Query: 82 EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE---AQQSAD----ENNRMCKVLENRA 134
+A +A N+ + IEE KSE ++KLLE +Q + E + C +L+
Sbjct: 661 KARLADKNKIYESIEE--AKSEAMK-EMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDL 717
Query: 135 QQDEERMDQLTNQLKEARLLAEDADG---KSDEVSRKLAFVEDELEVAEDRVKSGDAKIS 191
+Q ++++++L LK+ +L ED K ++ ++K +++L++ +V + K+S
Sbjct: 718 KQSQQKINEL---LKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNT--LKMS 772
Query: 192 ELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQK 251
E++LK N L ++++ EK N + + K +
Sbjct: 773 --EKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVR 830
Query: 252 EV-DRLEDELGINKD---RYKSLADEMDSTFAEL 281
E+ + E++ + K+ + + L DE DS A+L
Sbjct: 831 ELKEECEEKTKLGKELQQKKQELQDERDSLAAQL 864
Score = 50.0 bits (114), Expect = 9e-06
Identities = 34/162 (20%), Positives = 70/162 (43%), Gaps = 3/162 (1%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRE---LQKKLAQVEEDLILN 60
I+KK+ ++ N M + EQ+ + N R EK +E+ E L+K + L
Sbjct: 394 IQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEITLRKSVESALRQLERE 453
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K L+ N + + K + + ++ EDL+K + S + +K+ + Q+
Sbjct: 454 KALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQL 513
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
DE N + + + A + + + + Q+++ D K+
Sbjct: 514 DETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKN 555
Score = 49.6 bits (113), Expect = 1e-05
Identities = 43/188 (22%), Positives = 86/188 (45%), Gaps = 9/188 (4%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQL-TATEAEVAALNRKV--- 92
+ + E+QKKL +EE L N++ QA ++LE+K K + T E L ++
Sbjct: 385 DSIQSRKNEIQKKLYTLEEHL---SNEM-QAKEELEQKCKSVNTRLEKTAKELEEEITLR 440
Query: 93 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 152
+ +E L + E Q K E Q+ AD + LEN +++++ L + + ++
Sbjct: 441 KSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQ 500
Query: 153 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEE 212
+ E + ++ A + E + A R++ A+ S+ ++L+ L+ E
Sbjct: 501 ISTEKVNQLQRQLDETNALLRTESDTAA-RLRKTQAESSKQIQQLESNNRDLQDKNCLLE 559
Query: 213 KANQRVEE 220
A ++E+
Sbjct: 560 TAKLKLEK 567
Score = 48.4 bits (110), Expect = 3e-05
Identities = 47/223 (21%), Positives = 101/223 (45%), Gaps = 15/223 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADT----CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
+K+K++ + LE + D +Q+ + + + +NE+VR L K+ Q + L
Sbjct: 695 LKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCL 754
Query: 60 NKNKLE---QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+N L+ Q L+ EKQL + + +++ +L K E + Q K L+
Sbjct: 755 TQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRK-ERQDADGQMKELQD 813
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
Q A++ + + + ++ +E ++ T KE + ++ + D ++ +L +
Sbjct: 814 QLEAEQ--YFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKA 871
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ + + + S+LE+E K+ +K LE+ E A + E
Sbjct: 872 DSEQLARSIAEEQYSDLEKE-KI----MKELEIKEMMARHKQE 909
Score = 46.8 bits (106), Expect = 9e-05
Identities = 59/284 (20%), Positives = 108/284 (38%), Gaps = 16/284 (5%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRA--EKVNEEVRELQKKLA------QVEEDLI 58
K+ LE++ A KA ++ + E +E ++E++KKL Q E+L+
Sbjct: 644 KVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLL 703
Query: 59 LNKNK-LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
L K + DL++ ++++ + LN V+ + +E+ ++ Q L
Sbjct: 704 LEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQT 763
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
Q + K L+ E L Q E R +DADG+ E ++D+LE
Sbjct: 764 QQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKE-------LQDQLE 816
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXX 237
+ ++ EL+EE + K L+ +++ +
Sbjct: 817 AEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQL 876
Query: 238 XXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ L+KE E E+ R+K E D+T A L
Sbjct: 877 ARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASL 920
Score = 31.5 bits (68), Expect = 3.5
Identities = 41/218 (18%), Positives = 89/218 (40%), Gaps = 8/218 (3%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
K + ++ + ++ D+ + +++ +++ + EKVN+ LQ++L + L + +
Sbjct: 474 KKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQ----LQRQLDETNALLRTESDTAAR 529
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
K E KQ+ E+ L K +E K E+ Q L ++ + +
Sbjct: 530 LRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEI 589
Query: 127 CKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
L+ R EE + L E R L E E S + +L+V +
Sbjct: 590 INDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQS 649
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
++ +A+ + L +S+E ++ +A + +E+
Sbjct: 650 LEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEK 687
>AB210009-1|BAE06091.1| 1258|Homo sapiens PPFIA2 variant protein
protein.
Length = 1258
Score = 55.6 bits (128), Expect = 2e-07
Identities = 44/181 (24%), Positives = 82/181 (45%), Gaps = 4/181 (2%)
Query: 41 EEVRELQK-KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 99
+E+ E Q ++AQ++E L +++ + ++ E K L TE R +++
Sbjct: 285 QELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQK 344
Query: 100 EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDE---ERMDQLTNQLKEARLLAE 156
E EER T +++ L AQ+ + + M LEN E +M++ QL+E LAE
Sbjct: 345 EDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAE 404
Query: 157 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
++ + L VE EL + + + +EE ++ + L+ ++A Q
Sbjct: 405 QKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQ 464
Query: 217 R 217
R
Sbjct: 465 R 465
Score = 39.1 bits (87), Expect = 0.017
Identities = 33/203 (16%), Positives = 80/203 (39%), Gaps = 2/203 (0%)
Query: 18 AMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQ 77
++++ E++ AN + E+ +Q+K+A E LE + EK+
Sbjct: 209 SLERVSALEEELAAANQEIVALREQNVHIQRKMASSEGST--ESEHLEGMEPGQKVHEKR 266
Query: 78 LTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQD 137
L+ + ++ +++E LEK +++L E + + +
Sbjct: 267 LSNGSIDSTDETSQIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKT 326
Query: 138 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEEL 197
EE + ++EA ED + + + ++ + E D + +++ E L
Sbjct: 327 EEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAIL 386
Query: 198 KVVGNSLKSLEVSEEKANQRVEE 220
+ + + L+ E A Q++++
Sbjct: 387 RQMEEKNRQLQERLELAEQKLQQ 409
Score = 39.1 bits (87), Expect = 0.017
Identities = 48/264 (18%), Positives = 103/264 (39%), Gaps = 13/264 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
M +K+++ A+ +A+T + K ++RE + +EE +
Sbjct: 295 MAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTL 354
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
+ + A ++ E E+A ++Q+EE + +ER A+QKL + + A
Sbjct: 355 EKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKA 414
Query: 121 DENNRMCKVLENR---AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
+ + L R + EER + +++ E+ + + ++ E+ +
Sbjct: 415 ETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNK 474
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXX 237
D V D ++E E L++ LK + E+ N ++E
Sbjct: 475 RLSDTV---DRLLTESNERLQL---HLKERMAALEEKNVLIQE----SETFRKNLEESLH 524
Query: 238 XXXXXXKTVKKLQKEVDRLEDELG 261
+ ++KL+ E+D+L+ G
Sbjct: 525 DKERLAEEIEKLRSELDQLKMRTG 548
>AB015346-1|BAA88118.1| 864|Homo sapiens Eps15R protein.
Length = 864
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/144 (21%), Positives = 68/144 (47%)
Query: 76 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 135
K+L E+A L R+ +E+D+ + EE ++ E Q D + LE + Q
Sbjct: 384 KELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQ 443
Query: 136 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 195
++R+D++ Q + R + D K + ++ ++ ++ +++ E +KS + ++ +
Sbjct: 444 DAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKS 503
Query: 196 ELKVVGNSLKSLEVSEEKANQRVE 219
EL + LE S + ++E
Sbjct: 504 ELNRLQQEETQLEQSIQAGRVQLE 527
Score = 53.2 bits (122), Expect = 1e-06
Identities = 33/179 (18%), Positives = 83/179 (46%), Gaps = 7/179 (3%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+ +++E+ +LQ++ +E+D+ + + Q +++E + L + + L + Q +
Sbjct: 387 DDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQ 446
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA----- 151
+ L++ +++ + L + +Q + +M L+ + Q E + + L A
Sbjct: 447 DRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSELN 506
Query: 152 RLLAEDAD-GKSDEVSR-KLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
RL E+ +S + R +L + L+ +D + +K+S+L E + SL+ +
Sbjct: 507 RLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYD 565
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/167 (20%), Positives = 81/167 (48%), Gaps = 12/167 (7%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
+D +Q ++ +K +A D+ D +QQ K+ + + ++++K + +
Sbjct: 428 LDRETSSLQELEAQKQDAQDRLDEMDQQKA-------KLRDMLSDVRQKCQDETQMISSL 480
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K +++ DL+ +E L ++E+ L ++ Q+E+ ++ + T + L Q
Sbjct: 481 KTQIQSQESDLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEI 540
Query: 121 DE-NNRMCKVLENR--AQQDEERMDQLTNQLKEARL--LAEDADGKS 162
++ +++ ++ E+R A + E+ DQ+ + A L LA ++G S
Sbjct: 541 NQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSEGVS 587
Score = 37.5 bits (83), Expect = 0.053
Identities = 38/195 (19%), Positives = 94/195 (48%), Gaps = 28/195 (14%)
Query: 41 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 100
+E+ ++ +++AQ++ + K LEQ D+ EKE+ + +EV Q+++ DL+
Sbjct: 384 KELDDISQEIAQLQRE----KYSLEQ---DIREKEEAIRQKTSEV-------QELQNDLD 429
Query: 101 KS-------EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL--KEA 151
+ E + AQ +L E Q + M + + Q + + + L Q+ +E+
Sbjct: 430 RETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQES 489
Query: 152 RLLAEDAD---GKSD--EVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKS 206
L +++ D KS+ + ++ +E ++ ++++ + ++E+ + L
Sbjct: 490 DLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQ 549
Query: 207 LEVSEEKANQRVEEF 221
L S ++A++ +E++
Sbjct: 550 LHESRQEAHRSLEQY 564
Score = 36.3 bits (80), Expect = 0.12
Identities = 31/118 (26%), Positives = 57/118 (48%), Gaps = 4/118 (3%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 85
EQ R+ + EV+ELQ L + L + + + A L+E ++Q +
Sbjct: 404 EQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDML 463
Query: 86 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQ 143
+ + +K Q E + S + +Q+ L++Q+ D+ NR L NR QQ+E +++Q
Sbjct: 464 SDVRQKCQD-ETQMISSLKTQIQSQESDLKSQE--DDLNRAKSEL-NRLQQEETQLEQ 517
Score = 34.7 bits (76), Expect = 0.37
Identities = 29/161 (18%), Positives = 73/161 (45%), Gaps = 6/161 (3%)
Query: 14 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE-EDLILNKNKLEQANKDLE 72
EK+ A+ + T E Q +L E + + E QK+ AQ +++ K KL D+
Sbjct: 409 EKEEAI-RQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVR 467
Query: 73 EK----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
+K + +++ + ++ + ++ E+DL +++ QQ+ + +QS +
Sbjct: 468 QKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGRVQLE 527
Query: 129 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 169
+ + ++ ++Q ++L + ++A ++ + L
Sbjct: 528 TIIKSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYDQVL 568
>AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein.
Length = 1428
Score = 55.6 bits (128), Expect = 2e-07
Identities = 64/274 (23%), Positives = 130/274 (47%), Gaps = 28/274 (10%)
Query: 26 EQQARDANLRAEKVNEEVRELQKKLAQVEEDL----ILNKNKLEQANKDLEEKEKQLTAT 81
E+ ++ + KV E R+LQ++ +E++ I +L+ + LE++E + AT
Sbjct: 692 EEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKAT 751
Query: 82 EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE---AQQSAD----ENNRMCKVLENRA 134
+A +A N+ + IEE KSE ++KLLE +Q + E + C +L+
Sbjct: 752 KARLADKNKIYESIEE--AKSEAMK-EMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDL 808
Query: 135 QQDEERMDQLTNQLKEARLLAEDADG---KSDEVSRKLAFVEDELEVAEDRVKSGDAKIS 191
+Q ++++++L LK+ +L ED K ++ ++K +++L++ +V + K+S
Sbjct: 809 KQSQQKINEL---LKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNT--LKMS 863
Query: 192 ELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQK 251
E++LK N L ++++ EK N + + K +
Sbjct: 864 --EKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVR 921
Query: 252 EV-DRLEDELGINKD---RYKSLADEMDSTFAEL 281
E+ + E++ + K+ + + L DE DS A+L
Sbjct: 922 ELKEECEEKTKLGKELQQKKQELQDERDSLAAQL 955
Score = 54.4 bits (125), Expect = 4e-07
Identities = 46/185 (24%), Positives = 88/185 (47%), Gaps = 9/185 (4%)
Query: 40 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQL-TATEAEVAALNRKV---QQI 95
NEE +E+QKKL +EE L N++ QA ++LE+K K + T E L ++ + +
Sbjct: 479 NEESQEIQKKLYTLEEHL---SNEM-QAKEELEQKCKSVNTRLEKTAKELEEEITLRKSV 534
Query: 96 EEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLA 155
E L + E Q K E Q+ AD + LEN +++++ L + + +++
Sbjct: 535 ESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQIST 594
Query: 156 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKAN 215
E + ++ A + E + A R++ A+ S+ ++L+ L+ E A
Sbjct: 595 EKVNQLQRQLDETNALLRTESDTAA-RLRKTQAESSKQIQQLESNNRDLQDKNCLLETAK 653
Query: 216 QRVEE 220
++E+
Sbjct: 654 LKLEK 658
Score = 50.0 bits (114), Expect = 9e-06
Identities = 34/162 (20%), Positives = 70/162 (43%), Gaps = 3/162 (1%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRE---LQKKLAQVEEDLILN 60
I+KK+ ++ N M + EQ+ + N R EK +E+ E L+K + L
Sbjct: 485 IQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEITLRKSVESALRQLERE 544
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K L+ N + + K + + ++ EDL+K + S + +K+ + Q+
Sbjct: 545 KALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQL 604
Query: 121 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 162
DE N + + + A + + + + Q+++ D K+
Sbjct: 605 DETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKN 646
Score = 48.4 bits (110), Expect = 3e-05
Identities = 47/223 (21%), Positives = 101/223 (45%), Gaps = 15/223 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADT----CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 59
+K+K++ + LE + D +Q+ + + + +NE+VR L K+ Q + L
Sbjct: 786 LKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCL 845
Query: 60 NKNKLE---QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
+N L+ Q L+ EKQL + + +++ +L K E + Q K L+
Sbjct: 846 TQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRK-ERQDADGQMKELQD 904
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
Q A++ + + + ++ +E ++ T KE + ++ + D ++ +L +
Sbjct: 905 QLEAEQ--YFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKA 962
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
+ + + + S+LE+E K+ +K LE+ E A + E
Sbjct: 963 DSEQLARSIAEEQYSDLEKE-KI----MKELEIKEMMARHKQE 1000
Score = 46.8 bits (106), Expect = 9e-05
Identities = 59/284 (20%), Positives = 108/284 (38%), Gaps = 16/284 (5%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRA--EKVNEEVRELQKKLA------QVEEDLI 58
K+ LE++ A KA ++ + E +E ++E++KKL Q E+L+
Sbjct: 735 KVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLL 794
Query: 59 LNKNK-LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 117
L K + DL++ ++++ + LN V+ + +E+ ++ Q L
Sbjct: 795 LEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQT 854
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 177
Q + K L+ E L Q E R +DADG+ E ++D+LE
Sbjct: 855 QQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKE-------LQDQLE 907
Query: 178 VAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEFXXXXXXXXXXXXXXXX 237
+ ++ EL+EE + K L+ +++ +
Sbjct: 908 AEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQL 967
Query: 238 XXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMDSTFAEL 281
+ L+KE E E+ R+K E D+T A L
Sbjct: 968 ARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASL 1011
Score = 31.5 bits (68), Expect = 3.5
Identities = 41/218 (18%), Positives = 89/218 (40%), Gaps = 8/218 (3%)
Query: 7 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 66
K + ++ + ++ D+ + +++ +++ + EKVN+ LQ++L + L + +
Sbjct: 565 KKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQ----LQRQLDETNALLRTESDTAAR 620
Query: 67 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 126
K E KQ+ E+ L K +E K E+ Q L ++ + +
Sbjct: 621 LRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEI 680
Query: 127 CKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
L+ R EE + L E R L E E S + +L+V +
Sbjct: 681 INDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQS 740
Query: 183 VKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
++ +A+ + L +S+E ++ +A + +E+
Sbjct: 741 LEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEK 778
>X04627-1|CAA28300.1| 258|Homo sapiens beta-myosin heavy chain
protein.
Length = 258
Score = 55.2 bits (127), Expect = 2e-07
Identities = 43/203 (21%), Positives = 103/203 (50%), Gaps = 19/203 (9%)
Query: 2 DAIKKKMQAMKLEKD--NAMDKADT-CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 58
+A ++ + ++ E+D N + KA EQQ D E+ + +L++ ++E DL
Sbjct: 65 EAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 124
Query: 59 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 118
L + + D ++ +++L + E+ ALN +++ E+ G+ QK L+ Q
Sbjct: 125 LTQESIMDLENDKQQLDERLKKKDFELNALNARIED--------EQALGSQLQKKLKELQ 176
Query: 119 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 178
+ ++ + ++ ++ +D+L ++K + AE+A+ +++ K V+ EL+
Sbjct: 177 TEEDRKNLLRL--------QDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDE 228
Query: 179 AEDRVKSGDAKISELEEELKVVG 201
AE+R ++++++L + + +G
Sbjct: 229 AEERADIAESQVNKLRAKSRDIG 251
Score = 54.0 bits (124), Expect = 6e-07
Identities = 51/197 (25%), Positives = 99/197 (50%), Gaps = 17/197 (8%)
Query: 31 DANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALN 89
D R + + EE+ L + +A++ ++ + +QA DL+ E++K T T+A+V
Sbjct: 34 DFRQRVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV---- 89
Query: 90 RKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLT 145
K++Q +DLE S E+ + L A++ + + ++ + LEN QQ +ER+ +
Sbjct: 90 -KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKD 148
Query: 146 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLK 205
+L ED ++ +KL EL+ EDR ++ +L ++L++ + K
Sbjct: 149 FELNALNARIEDEQALGSQLQKKL----KELQTEEDR--KNLLRLQDLVDKLQLKVKAYK 202
Query: 206 -SLEVSEEKANQRVEEF 221
E +EE+AN + +F
Sbjct: 203 RQAEEAEEQANTNLSKF 219
>U80458-1|AAD00355.1| 1604|Homo sapiens microtubule associated protein
1A protein.
Length = 1604
Score = 55.2 bits (127), Expect = 2e-07
Identities = 55/200 (27%), Positives = 97/200 (48%), Gaps = 11/200 (5%)
Query: 13 LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 72
LE ++ DT Q +D L + NE V++ K L Q DL LEQ +K LE
Sbjct: 1291 LEHKEVVEPKDTAIYQ-KDEALHVK--NEAVKQQDKALEQKGRDLEQKDTALEQKDKALE 1347
Query: 73 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN-NRMCKVLE 131
K+K L E + AL +K +I E+ +K+ E+ TA ++ + + D++ + +VLE
Sbjct: 1348 PKDKDL---EEKDKALEQK-DKIPEEKDKALEQKDTALEQKDKTLEPKDKDLEQKDRVLE 1403
Query: 132 NRAQQDEERMDQLTNQLKEARLLA-ED--ADGKSDEVSRKLAFVEDELEVAEDRVKSGDA 188
+ + EE+ L +++ A ED A+ K ++ + E + + E + K +
Sbjct: 1404 QKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEK 1463
Query: 189 KISELEEELKVVGNSLKSLE 208
K LE++ +G ++LE
Sbjct: 1464 KDQALEQKYWALGQKDEALE 1483
Score = 52.0 bits (119), Expect = 2e-06
Identities = 46/221 (20%), Positives = 107/221 (48%), Gaps = 5/221 (2%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE-DLIL-N 60
AI +K +A+ ++ + + EQ+ RD + + ++ + L+ K +EE D L
Sbjct: 1303 AIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQ 1362
Query: 61 KNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 119
K+K+ E+ +K LE+K+ L + + ++ ++Q + LE+ +E+ + K L+ +
Sbjct: 1363 KDKIPEEKDKALEQKDTALEQKDKTLEPKDKDLEQKDRVLEQ-KEKIPEEKDKALDQKVR 1421
Query: 120 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE-VSRKLAFVEDELEV 178
+ E+ + +D E+ D+ Q +A+ + K D+ + +K + + E
Sbjct: 1422 SVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEA 1481
Query: 179 AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
E +++ + E+E V + + ++ EEK+ ++V+
Sbjct: 1482 LEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVK 1522
Score = 40.3 bits (90), Expect = 0.007
Identities = 35/156 (22%), Positives = 80/156 (51%), Gaps = 8/156 (5%)
Query: 47 QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE---KSE 103
QKK + +++++ K+K + + +E K+ + + + N V+Q ++ LE +
Sbjct: 1273 QKKEPEPKDEVLTQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDL 1332
Query: 104 ERSGTAQQKLLEAQQSADEN-NRMCKVLENRAQQDEERMDQLTNQLKEARLLAED--ADG 160
E+ TA ++ +A + D++ K LE + + EE+ D+ Q K+ L +D +
Sbjct: 1333 EQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEK-DKALEQ-KDTALEQKDKTLEP 1390
Query: 161 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEE 196
K ++ +K +E + ++ E++ K+ D K+ +E +
Sbjct: 1391 KDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHK 1426
>BC109126-1|AAI09127.1| 872|Homo sapiens chromosome 10 open reading
frame 80 protein.
Length = 872
Score = 55.2 bits (127), Expect = 2e-07
Identities = 44/202 (21%), Positives = 103/202 (50%), Gaps = 9/202 (4%)
Query: 22 ADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT 81
A T EQQ ++ E+ + + Q+++ Q + + K E+ K+L++ + + +
Sbjct: 177 AQTTEQQ-QETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSR 235
Query: 82 EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
+ E+ AL + VQ+ +E+L+K E++ +QK+L +++A E + ++ + QQ+ E+
Sbjct: 236 QTEIKALQQYVQKSKEELQKLEQQ--LKEQKILN-ERAAKELEQF-QMRNAKLQQENEQH 291
Query: 142 DQLTNQL-KEARLLAEDADGKSDEVSRKLAFVEDELEVAED---RVKSGDAKISELEEEL 197
+ QL +E + A + K +EV + + ++ E ++ + + +E+E+
Sbjct: 292 SLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHK 351
Query: 198 KVVGNSLKSLEVSEEKANQRVE 219
+ + N + LE E + ++ E
Sbjct: 352 ETLKNQIVGLEREVEASKKQAE 373
Score = 48.8 bits (111), Expect = 2e-05
Identities = 45/210 (21%), Positives = 97/210 (46%), Gaps = 14/210 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ---KKLAQVEEDL 57
MD+ + +++A++ + ++ EQQ ++ + E+ +E+ + Q KL Q E
Sbjct: 232 MDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQH 291
Query: 58 ILNKNKLEQANK----DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
L +L Q N+ +L+ KE+++ ++ LN+ +QI + L +E++ +Q
Sbjct: 292 SLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHK 351
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQ---LKEARLLAEDADGKSDEV----S 166
+ R + + +A+ D + MD+L + L + L A +A K ++
Sbjct: 352 ETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHE 411
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEEE 196
+ +E E++ +D + I LE+E
Sbjct: 412 QAKRNLEGEIQNYKDEAQKQRKIIFHLEKE 441
Score = 44.0 bits (99), Expect = 6e-04
Identities = 42/239 (17%), Positives = 93/239 (38%), Gaps = 14/239 (5%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+++ EV +L++ LAQ E +E E+ E ++ +++QQ +
Sbjct: 163 DQLLSEVVKLRESLAQTTE--------------QQQETERSKEEAEHAISQFQQEIQQRQ 208
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
+ + + +++L + Q D K L+ Q+ +E + +L QLKE ++L E
Sbjct: 209 NEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNE 268
Query: 157 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
A + ++ + A ++ E E + + + ELK + + + K N+
Sbjct: 269 RAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNK 328
Query: 217 RVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMD 275
E+ + L++EV+ + + +++ L E D
Sbjct: 329 IREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERD 387
Score = 41.9 bits (94), Expect = 0.002
Identities = 47/216 (21%), Positives = 100/216 (46%), Gaps = 23/216 (10%)
Query: 29 ARDANLRAE-KVNEEVRELQKKLAQVEEDLILN-KNKLEQANK------DLEEKEKQ-LT 79
A+ L AE VN KL+Q ++ I + K ++E+A K D E+K K+ +
Sbjct: 62 AKCRELNAEIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETIL 121
Query: 80 ATEAEVAALNRKVQQ-----------IEEDLEKSEERSGTAQQKLLEA---QQSADENNR 125
A + E+ L + V+Q I + L EE + Q L E ++S +
Sbjct: 122 ALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTE 181
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
+ E ++ E + Q ++++ + A K +++ ++L ++ +++ + +K+
Sbjct: 182 QQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKA 241
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
+ + +EEL+ + LK ++ E+A + +E+F
Sbjct: 242 LQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQF 277
Score = 40.3 bits (90), Expect = 0.007
Identities = 34/153 (22%), Positives = 67/153 (43%), Gaps = 6/153 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADT--CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+K ++ ++EK+ KA+ QQA + EK E R+L + +A+ + + + K
Sbjct: 541 VKLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAEADGERLRQK 600
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL----LEAQ 117
+L+Q + + QL E+A L K++ + L K E + + + LE +
Sbjct: 601 KELDQVISERDILGSQLVRRNDELALLYEKIKIQQSVLNKGESQYNQRLEDMRILRLEIK 660
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKE 150
+ E + + + N + +E LKE
Sbjct: 661 KLRREKGILARSMANVEELRQEFFHMQRELLKE 693
Score = 38.3 bits (85), Expect = 0.030
Identities = 45/226 (19%), Positives = 93/226 (41%), Gaps = 9/226 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ--VEEDLIL 59
+ I KK+ + +K +T + Q E ++ EL +K + E IL
Sbjct: 331 EQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQA-ELDRKAMDELLRERDIL 389
Query: 60 NKNKLEQANK-----DLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
NKN L+ N DL + +Q E E+ + Q+ + + E+ +
Sbjct: 390 NKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQA 449
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
+ Q N KV E + +++ + +LK+ + L E + S+ L +
Sbjct: 450 SDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVEAQ 509
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
DE+ + ++K ++ EL+E++ ++L L + +++ + E
Sbjct: 510 DEITDMKRKLKIMIHQVDELKEDISAKESALVKLHLEQQRIEKEKE 555
Score = 38.3 bits (85), Expect = 0.030
Identities = 38/227 (16%), Positives = 102/227 (44%), Gaps = 7/227 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A KK+ + + D + + D + A +K + V+ ++ +E ++
Sbjct: 365 VEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNY 424
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K++ ++ K + EK+ + + L +KV ED++ E + ++K+ E++
Sbjct: 425 KDEAQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKL 484
Query: 121 DENNRMCKVLEN----RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK-LAFVEDE 175
+ + + + + ++ E D++T+ ++ +++ D +++S K A V+
Sbjct: 485 KQQQNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESALVKLH 544
Query: 176 LEV--AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
LE E ++ A++ +L ++ + ++ E E K + + E
Sbjct: 545 LEQQRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAE 591
Score = 35.9 bits (79), Expect = 0.16
Identities = 40/202 (19%), Positives = 99/202 (49%), Gaps = 26/202 (12%)
Query: 11 MKLEKDNAMDKADTCEQQARDANL--RAEKVNEEVRELQKKLAQVEE---DLILNKNKLE 65
+KL++ + +A ++ NL +++ + R+L+ + QV+E D+ ++ L
Sbjct: 482 IKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESALV 541
Query: 66 QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
+ + + + EK+ +AE+ L ++ + + +EK E ++KLL AD
Sbjct: 542 KLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQE----AEERKLLRIIAEAD---- 593
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
R +Q +E +DQ+ + E +L ++DE LA + +++++ + +
Sbjct: 594 -----GERLRQKKE-LDQV---ISERDILGSQLVRRNDE----LALLYEKIKIQQSVLNK 640
Query: 186 GDAKISELEEELKVVGNSLKSL 207
G+++ ++ E+++++ +K L
Sbjct: 641 GESQYNQRLEDMRILRLEIKKL 662
>BC036225-1|AAH36225.1| 872|Homo sapiens chromosome 10 open reading
frame 80 protein.
Length = 872
Score = 55.2 bits (127), Expect = 2e-07
Identities = 44/202 (21%), Positives = 103/202 (50%), Gaps = 9/202 (4%)
Query: 22 ADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT 81
A T EQQ ++ E+ + + Q+++ Q + + K E+ K+L++ + + +
Sbjct: 177 AQTTEQQ-QETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSR 235
Query: 82 EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
+ E+ AL + VQ+ +E+L+K E++ +QK+L +++A E + ++ + QQ+ E+
Sbjct: 236 QTEIKALQQYVQKSKEELQKLEQQ--LKEQKILN-ERAAKELEQF-QMRNAKLQQENEQH 291
Query: 142 DQLTNQL-KEARLLAEDADGKSDEVSRKLAFVEDELEVAED---RVKSGDAKISELEEEL 197
+ QL +E + A + K +EV + + ++ E ++ + + +E+E+
Sbjct: 292 SLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHK 351
Query: 198 KVVGNSLKSLEVSEEKANQRVE 219
+ + N + LE E + ++ E
Sbjct: 352 ETLKNQIVGLEREVEASKKQAE 373
Score = 48.8 bits (111), Expect = 2e-05
Identities = 45/210 (21%), Positives = 97/210 (46%), Gaps = 14/210 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ---KKLAQVEEDL 57
MD+ + +++A++ + ++ EQQ ++ + E+ +E+ + Q KL Q E
Sbjct: 232 MDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQH 291
Query: 58 ILNKNKLEQANK----DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
L +L Q N+ +L+ KE+++ ++ LN+ +QI + L +E++ +Q
Sbjct: 292 SLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHK 351
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQ---LKEARLLAEDADGKSDEV----S 166
+ R + + +A+ D + MD+L + L + L A +A K ++
Sbjct: 352 ETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHE 411
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEEE 196
+ +E E++ +D + I LE+E
Sbjct: 412 QAKRNLEGEIQNYKDEAQKQRKIIFHLEKE 441
Score = 44.0 bits (99), Expect = 6e-04
Identities = 42/239 (17%), Positives = 93/239 (38%), Gaps = 14/239 (5%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+++ EV +L++ LAQ E +E E+ E ++ +++QQ +
Sbjct: 163 DQLLSEVVKLRESLAQTTE--------------QQQETERSKEEAEHAISQFQQEIQQRQ 208
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
+ + + +++L + Q D K L+ Q+ +E + +L QLKE ++L E
Sbjct: 209 NEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNE 268
Query: 157 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
A + ++ + A ++ E E + + + ELK + + + K N+
Sbjct: 269 RAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNK 328
Query: 217 RVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMD 275
E+ + L++EV+ + + +++ L E D
Sbjct: 329 IREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERD 387
Score = 41.9 bits (94), Expect = 0.002
Identities = 47/216 (21%), Positives = 100/216 (46%), Gaps = 23/216 (10%)
Query: 29 ARDANLRAE-KVNEEVRELQKKLAQVEEDLILN-KNKLEQANK------DLEEKEKQ-LT 79
A+ L AE VN KL+Q ++ I + K ++E+A K D E+K K+ +
Sbjct: 62 AKCRELNAEIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETIL 121
Query: 80 ATEAEVAALNRKVQQ-----------IEEDLEKSEERSGTAQQKLLEA---QQSADENNR 125
A + E+ L + V+Q I + L EE + Q L E ++S +
Sbjct: 122 ALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTE 181
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
+ E ++ E + Q ++++ + A K +++ ++L ++ +++ + +K+
Sbjct: 182 QQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKA 241
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
+ + +EEL+ + LK ++ E+A + +E+F
Sbjct: 242 LQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQF 277
Score = 40.3 bits (90), Expect = 0.007
Identities = 34/153 (22%), Positives = 67/153 (43%), Gaps = 6/153 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADT--CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+K ++ ++EK+ KA+ QQA + EK E R+L + +A+ + + + K
Sbjct: 541 VKLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAEADGERLRQK 600
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL----LEAQ 117
+L+Q + + QL E+A L K++ + L K E + + + LE +
Sbjct: 601 KELDQVISERDILGSQLVRRNDELALLYEKIKIQQSVLNKGESQYNQRLEDMRILRLEIK 660
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKE 150
+ E + + + N + +E LKE
Sbjct: 661 KLRREKGILARSMANVEELRQEFFHMQRELLKE 693
Score = 38.3 bits (85), Expect = 0.030
Identities = 45/226 (19%), Positives = 93/226 (41%), Gaps = 9/226 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ--VEEDLIL 59
+ I KK+ + +K +T + Q E ++ EL +K + E IL
Sbjct: 331 EQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQA-ELDRKAMDELLRERDIL 389
Query: 60 NKNKLEQANK-----DLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
NKN L+ N DL + +Q E E+ + Q+ + + E+ +
Sbjct: 390 NKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQA 449
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
+ Q N KV E + +++ + +LK+ + L E + S+ L +
Sbjct: 450 SDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVEAQ 509
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
DE+ + ++K ++ EL+E++ ++L L + +++ + E
Sbjct: 510 DEITDMKRKLKIMIHQVDELKEDISAKESALVKLHLEQQRIEKEKE 555
Score = 38.3 bits (85), Expect = 0.030
Identities = 38/227 (16%), Positives = 102/227 (44%), Gaps = 7/227 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A KK+ + + D + + D + A +K + V+ ++ +E ++
Sbjct: 365 VEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNY 424
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K++ ++ K + EK+ + + L +KV ED++ E + ++K+ E++
Sbjct: 425 KDEAQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKL 484
Query: 121 DENNRMCKVLEN----RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK-LAFVEDE 175
+ + + + + ++ E D++T+ ++ +++ D +++S K A V+
Sbjct: 485 KQQQNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESALVKLH 544
Query: 176 LEV--AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
LE E ++ A++ +L ++ + ++ E E K + + E
Sbjct: 545 LEQQRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAE 591
Score = 35.9 bits (79), Expect = 0.16
Identities = 40/202 (19%), Positives = 99/202 (49%), Gaps = 26/202 (12%)
Query: 11 MKLEKDNAMDKADTCEQQARDANL--RAEKVNEEVRELQKKLAQVEE---DLILNKNKLE 65
+KL++ + +A ++ NL +++ + R+L+ + QV+E D+ ++ L
Sbjct: 482 IKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESALV 541
Query: 66 QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
+ + + + EK+ +AE+ L ++ + + +EK E ++KLL AD
Sbjct: 542 KLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQE----AEERKLLRIIAEAD---- 593
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
R +Q +E +DQ+ + E +L ++DE LA + +++++ + +
Sbjct: 594 -----GERLRQKKE-LDQV---ISERDILGSQLVRRNDE----LALLYEKIKIQQSVLNK 640
Query: 186 GDAKISELEEELKVVGNSLKSL 207
G+++ ++ E+++++ +K L
Sbjct: 641 GESQYNQRLEDMRILRLEIKKL 662
>BC028423-1|AAH28423.1| 1022|Homo sapiens PMFBP1 protein protein.
Length = 1022
Score = 55.2 bits (127), Expect = 2e-07
Identities = 41/205 (20%), Positives = 97/205 (47%), Gaps = 1/205 (0%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
+K+ + ++ E +N + C Q + + + +++L K++A +E L+ + +
Sbjct: 656 LKENSRKLEEENENLRAELQCCSTQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQ 715
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
L++A + E+ Q T T+ AL+RK ++DL ++ E+ + QQS +
Sbjct: 716 LDKALQK-EKHYLQTTITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQT 774
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
LE EERM +L +L++ R ++++ + +KL + ++ + +
Sbjct: 775 QEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQH 834
Query: 184 KSGDAKISELEEELKVVGNSLKSLE 208
++ ++ EE+L+ + +L+
Sbjct: 835 QNDLKMLAAKEEQLREFQEEMAALK 859
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/217 (20%), Positives = 103/217 (47%), Gaps = 8/217 (3%)
Query: 12 KLEKDNAMDK--ADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE-DLILNKNKLEQAN 68
KL+K +DK ADT ++ R+ + ++ + +E +VEE L L++ + N
Sbjct: 511 KLQKGLLLDKQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSEALRKLEN 570
Query: 69 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 128
D E+++ Q T E ++ +N + +I+ + ++ L EA + ++ K
Sbjct: 571 SDKEKRQLQKTVAEQDM-KMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLK 629
Query: 129 VLENRAQQDEERMDQLTNQLKEA-RLLAEDA---DGKSDEVSRKLAFVEDELEVAEDRVK 184
+ + E ++ L + K+ + L E++ + +++ + +L +LE + ++
Sbjct: 630 KSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCSTQLESSLNKYN 689
Query: 185 SGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
+ I +L +E+ + SL SL+ +KA Q+ + +
Sbjct: 690 TSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHY 726
Score = 49.2 bits (112), Expect = 2e-05
Identities = 62/293 (21%), Positives = 128/293 (43%), Gaps = 36/293 (12%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
IKK ++ ++ +KD+ + + +D + E V+E+ R + K + ++E DL + +
Sbjct: 304 IKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSEQKRNIMKDMMKLELDLHGLREE 363
Query: 64 ----LEQANKD-------LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 112
+E+ +KD L+E + + T T+ ++ +Q+ +E L++ E++ Q
Sbjct: 364 TSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNS 423
Query: 113 LLEAQQSADENNRMCKVLE---NRAQQDEER----------MDQLTNQLKEA----RLLA 155
LL+ ++ ++ M LE A+QD+ + + +L N L+EA RL
Sbjct: 424 LLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQERLAG 483
Query: 156 E-DADGKSDEVSRKLAFVEDELEVAEDRVKSG---DAK----ISELEEELKVVGNSLKSL 207
E A ++ + + A LE + +++ G D + I EL+ EL+++
Sbjct: 484 EAPAAQQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSMA 543
Query: 208 EVSEEKANQRVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDEL 260
E + +RVEE KTV + +++ + D +
Sbjct: 544 EKEQTSNRKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMNDMLDRI 596
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/139 (19%), Positives = 69/139 (49%), Gaps = 8/139 (5%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
DA+ +K A + + A++K + + + + + + + Q+K AQ+EE++I +
Sbjct: 737 DALSRKSAACQDDLTQALEKLNHVTSETKS-------LQQSLTQTQEKKAQLEEEIIAYE 789
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE-EDLEKSEERSGTAQQKLLEAQQSA 120
++++ N +L + +E EV A ++K++++ + L+ ++ + + +Q
Sbjct: 790 ERMKKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLR 849
Query: 121 DENNRMCKVLENRAQQDEE 139
+ M + EN + D+E
Sbjct: 850 EFQEEMAALKENLLEDDKE 868
Score = 35.1 bits (77), Expect = 0.28
Identities = 36/212 (16%), Positives = 92/212 (43%), Gaps = 13/212 (6%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
++ K + +K K++ E ++ + + + E R+L+++ + +L +
Sbjct: 621 LEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCSTQ 680
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
LE + ++ + E+A + ++ L+K+ ++ Q + +++ D
Sbjct: 681 LESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTI-TKEAYDAL 739
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
+R ++ Q E+++ +T++ K + + K A +E+E+ E+R+
Sbjct: 740 SRKSAACQDDLTQALEKLNHVTSETKSLQ-------QSLTQTQEKKAQLEEEIIAYEERM 792
Query: 184 KSGDAKISEL-----EEELKVVGNSLKSLEVS 210
K + ++ +L E EL+V K E+S
Sbjct: 793 KKLNTELRKLRGFHQESELEVHAFDKKLEEMS 824
Score = 35.1 bits (77), Expect = 0.28
Identities = 39/212 (18%), Positives = 92/212 (43%), Gaps = 9/212 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ + + ++++ +K E++ R +K+N E+R+L+ + E ++
Sbjct: 757 LNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQESELEVHAF 816
Query: 61 KNKLEQANKDLEEKEKQ-------LTATEAEVAALNRKVQQIEED-LEKSEERSGTAQQK 112
KLE+ + + + +KQ L A E ++ ++ ++E+ LE +E Q
Sbjct: 817 DKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQEEMAALKENLLEDDKEPCCLPQWS 876
Query: 113 L-LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
+ + + N+++ LE A+Q + ++L NQL+E G+ D + +
Sbjct: 877 VPKDTCRLYRGNDQIMTNLEQWAKQQKVANEKLGNQLREQVKYIAKLSGEKDHLHSVMVH 936
Query: 172 VEDELEVAEDRVKSGDAKISELEEELKVVGNS 203
++ E + + ++ K K +G S
Sbjct: 937 LQQENKKLKKEIEEKKMKAENTRLCTKALGPS 968
Score = 33.5 bits (73), Expect = 0.86
Identities = 38/165 (23%), Positives = 75/165 (45%), Gaps = 13/165 (7%)
Query: 41 EEVRELQKKLAQV------EEDLILN-KNKLEQANKDLEEKEKQLTATEAEVA---ALNR 90
+E +E QK+L++V ++DLI +NKL +N + E+EK L +A+ A A +R
Sbjct: 233 QEHQETQKRLSEVWQKVSQQDDLIQELRNKLACSNALVLEREKALIKLQADFASCTATHR 292
Query: 91 KVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE 150
E+ E ++ Q++ +E + K L + E Q N +K+
Sbjct: 293 YPPSSSEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSE---QKRNIMKD 349
Query: 151 ARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEE 195
L D G +E S + + ++ + + R++ + +E ++
Sbjct: 350 MMKLELDLHGLREETSAHIERKDKDITILQCRLQELQLEFTETQK 394
>AL355378-1|CAI15667.1| 872|Homo sapiens novel protein protein.
Length = 872
Score = 55.2 bits (127), Expect = 2e-07
Identities = 44/202 (21%), Positives = 103/202 (50%), Gaps = 9/202 (4%)
Query: 22 ADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT 81
A T EQQ ++ E+ + + Q+++ Q + + K E+ K+L++ + + +
Sbjct: 177 AQTTEQQ-QETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSR 235
Query: 82 EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
+ E+ AL + VQ+ +E+L+K E++ +QK+L +++A E + ++ + QQ+ E+
Sbjct: 236 QTEIKALQQYVQKSKEELQKLEQQ--LKEQKILN-ERAAKELEQF-QMRNAKLQQENEQH 291
Query: 142 DQLTNQL-KEARLLAEDADGKSDEVSRKLAFVEDELEVAED---RVKSGDAKISELEEEL 197
+ QL +E + A + K +EV + + ++ E ++ + + +E+E+
Sbjct: 292 SLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHK 351
Query: 198 KVVGNSLKSLEVSEEKANQRVE 219
+ + N + LE E + ++ E
Sbjct: 352 ETLKNQIVGLEREVEASKKQAE 373
Score = 48.8 bits (111), Expect = 2e-05
Identities = 45/210 (21%), Positives = 97/210 (46%), Gaps = 14/210 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ---KKLAQVEEDL 57
MD+ + +++A++ + ++ EQQ ++ + E+ +E+ + Q KL Q E
Sbjct: 232 MDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQH 291
Query: 58 ILNKNKLEQANK----DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
L +L Q N+ +L+ KE+++ ++ LN+ +QI + L +E++ +Q
Sbjct: 292 SLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHK 351
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQ---LKEARLLAEDADGKSDEV----S 166
+ R + + +A+ D + MD+L + L + L A +A K ++
Sbjct: 352 ETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHE 411
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEEE 196
+ +E E++ +D + I LE+E
Sbjct: 412 QAKRNLEGEIQNYKDEAQKQRKIIFHLEKE 441
Score = 44.0 bits (99), Expect = 6e-04
Identities = 42/239 (17%), Positives = 93/239 (38%), Gaps = 14/239 (5%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+++ EV +L++ LAQ E +E E+ E ++ +++QQ +
Sbjct: 163 DQLLSEVVKLRESLAQTTE--------------QQQETERSKEEAEHAISQFQQEIQQRQ 208
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
+ + + +++L + Q D K L+ Q+ +E + +L QLKE ++L E
Sbjct: 209 NEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNE 268
Query: 157 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
A + ++ + A ++ E E + + + ELK + + + K N+
Sbjct: 269 RAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNK 328
Query: 217 RVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMD 275
E+ + L++EV+ + + +++ L E D
Sbjct: 329 IREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERD 387
Score = 41.9 bits (94), Expect = 0.002
Identities = 47/216 (21%), Positives = 100/216 (46%), Gaps = 23/216 (10%)
Query: 29 ARDANLRAE-KVNEEVRELQKKLAQVEEDLILN-KNKLEQANK------DLEEKEKQ-LT 79
A+ L AE VN KL+Q ++ I + K ++E+A K D E+K K+ +
Sbjct: 62 AKCRELNAEIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETIL 121
Query: 80 ATEAEVAALNRKVQQ-----------IEEDLEKSEERSGTAQQKLLEA---QQSADENNR 125
A + E+ L + V+Q I + L EE + Q L E ++S +
Sbjct: 122 ALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTE 181
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
+ E ++ E + Q ++++ + A K +++ ++L ++ +++ + +K+
Sbjct: 182 QQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKA 241
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
+ + +EEL+ + LK ++ E+A + +E+F
Sbjct: 242 LQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQF 277
Score = 40.3 bits (90), Expect = 0.007
Identities = 34/153 (22%), Positives = 67/153 (43%), Gaps = 6/153 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADT--CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+K ++ ++EK+ KA+ QQA + EK E R+L + +A+ + + + K
Sbjct: 541 VKLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAEADGERLRQK 600
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL----LEAQ 117
+L+Q + + QL E+A L K++ + L K E + + + LE +
Sbjct: 601 KELDQVISERDILGSQLVRRNDELALLYEKIKIQQSVLNKGESQYNQRLEDMRILRLEIK 660
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKE 150
+ E + + + N + +E LKE
Sbjct: 661 KLRREKGILARSMANVEELRQEFFHMQRELLKE 693
Score = 38.3 bits (85), Expect = 0.030
Identities = 45/226 (19%), Positives = 93/226 (41%), Gaps = 9/226 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ--VEEDLIL 59
+ I KK+ + +K +T + Q E ++ EL +K + E IL
Sbjct: 331 EQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQA-ELDRKAMDELLRERDIL 389
Query: 60 NKNKLEQANK-----DLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
NKN L+ N DL + +Q E E+ + Q+ + + E+ +
Sbjct: 390 NKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQA 449
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
+ Q N KV E + +++ + +LK+ + L E + S+ L +
Sbjct: 450 SDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVEAQ 509
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
DE+ + ++K ++ EL+E++ ++L L + +++ + E
Sbjct: 510 DEITDMKRKLKIMIHQVDELKEDISAKESALVKLHLEQQRIEKEKE 555
Score = 38.3 bits (85), Expect = 0.030
Identities = 38/227 (16%), Positives = 102/227 (44%), Gaps = 7/227 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A KK+ + + D + + D + A +K + V+ ++ +E ++
Sbjct: 365 VEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNY 424
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K++ ++ K + EK+ + + L +KV ED++ E + ++K+ E++
Sbjct: 425 KDEAQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKL 484
Query: 121 DENNRMCKVLEN----RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK-LAFVEDE 175
+ + + + + ++ E D++T+ ++ +++ D +++S K A V+
Sbjct: 485 KQQQNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESALVKLH 544
Query: 176 LEV--AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
LE E ++ A++ +L ++ + ++ E E K + + E
Sbjct: 545 LEQQRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAE 591
Score = 35.9 bits (79), Expect = 0.16
Identities = 40/202 (19%), Positives = 99/202 (49%), Gaps = 26/202 (12%)
Query: 11 MKLEKDNAMDKADTCEQQARDANL--RAEKVNEEVRELQKKLAQVEE---DLILNKNKLE 65
+KL++ + +A ++ NL +++ + R+L+ + QV+E D+ ++ L
Sbjct: 482 IKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESALV 541
Query: 66 QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
+ + + + EK+ +AE+ L ++ + + +EK E ++KLL AD
Sbjct: 542 KLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQE----AEERKLLRIIAEAD---- 593
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
R +Q +E +DQ+ + E +L ++DE LA + +++++ + +
Sbjct: 594 -----GERLRQKKE-LDQV---ISERDILGSQLVRRNDE----LALLYEKIKIQQSVLNK 640
Query: 186 GDAKISELEEELKVVGNSLKSL 207
G+++ ++ E+++++ +K L
Sbjct: 641 GESQYNQRLEDMRILRLEIKKL 662
>AL162742-5|CAI12110.1| 872|Homo sapiens novel protein protein.
Length = 872
Score = 55.2 bits (127), Expect = 2e-07
Identities = 44/202 (21%), Positives = 103/202 (50%), Gaps = 9/202 (4%)
Query: 22 ADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT 81
A T EQQ ++ E+ + + Q+++ Q + + K E+ K+L++ + + +
Sbjct: 177 AQTTEQQ-QETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSR 235
Query: 82 EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERM 141
+ E+ AL + VQ+ +E+L+K E++ +QK+L +++A E + ++ + QQ+ E+
Sbjct: 236 QTEIKALQQYVQKSKEELQKLEQQ--LKEQKILN-ERAAKELEQF-QMRNAKLQQENEQH 291
Query: 142 DQLTNQL-KEARLLAEDADGKSDEVSRKLAFVEDELEVAED---RVKSGDAKISELEEEL 197
+ QL +E + A + K +EV + + ++ E ++ + + +E+E+
Sbjct: 292 SLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHK 351
Query: 198 KVVGNSLKSLEVSEEKANQRVE 219
+ + N + LE E + ++ E
Sbjct: 352 ETLKNQIVGLEREVEASKKQAE 373
Score = 48.8 bits (111), Expect = 2e-05
Identities = 45/210 (21%), Positives = 97/210 (46%), Gaps = 14/210 (6%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ---KKLAQVEEDL 57
MD+ + +++A++ + ++ EQQ ++ + E+ +E+ + Q KL Q E
Sbjct: 232 MDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQH 291
Query: 58 ILNKNKLEQANK----DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
L +L Q N+ +L+ KE+++ ++ LN+ +QI + L +E++ +Q
Sbjct: 292 SLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHK 351
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQ---LKEARLLAEDADGKSDEV----S 166
+ R + + +A+ D + MD+L + L + L A +A K ++
Sbjct: 352 ETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHE 411
Query: 167 RKLAFVEDELEVAEDRVKSGDAKISELEEE 196
+ +E E++ +D + I LE+E
Sbjct: 412 QAKRNLEGEIQNYKDEAQKQRKIIFHLEKE 441
Score = 44.0 bits (99), Expect = 6e-04
Identities = 42/239 (17%), Positives = 93/239 (38%), Gaps = 14/239 (5%)
Query: 37 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 96
+++ EV +L++ LAQ E +E E+ E ++ +++QQ +
Sbjct: 163 DQLLSEVVKLRESLAQTTE--------------QQQETERSKEEAEHAISQFQQEIQQRQ 208
Query: 97 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 156
+ + + +++L + Q D K L+ Q+ +E + +L QLKE ++L E
Sbjct: 209 NEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNE 268
Query: 157 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQ 216
A + ++ + A ++ E E + + + ELK + + + K N+
Sbjct: 269 RAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNK 328
Query: 217 RVEEFXXXXXXXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEMD 275
E+ + L++EV+ + + +++ L E D
Sbjct: 329 IREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERD 387
Score = 41.9 bits (94), Expect = 0.002
Identities = 47/216 (21%), Positives = 100/216 (46%), Gaps = 23/216 (10%)
Query: 29 ARDANLRAE-KVNEEVRELQKKLAQVEEDLILN-KNKLEQANK------DLEEKEKQ-LT 79
A+ L AE VN KL+Q ++ I + K ++E+A K D E+K K+ +
Sbjct: 62 AKCRELNAEIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETIL 121
Query: 80 ATEAEVAALNRKVQQ-----------IEEDLEKSEERSGTAQQKLLEA---QQSADENNR 125
A + E+ L + V+Q I + L EE + Q L E ++S +
Sbjct: 122 ALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTE 181
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
+ E ++ E + Q ++++ + A K +++ ++L ++ +++ + +K+
Sbjct: 182 QQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKA 241
Query: 186 GDAKISELEEELKVVGNSLKSLEVSEEKANQRVEEF 221
+ + +EEL+ + LK ++ E+A + +E+F
Sbjct: 242 LQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQF 277
Score = 40.3 bits (90), Expect = 0.007
Identities = 34/153 (22%), Positives = 67/153 (43%), Gaps = 6/153 (3%)
Query: 4 IKKKMQAMKLEKDNAMDKADT--CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
+K ++ ++EK+ KA+ QQA + EK E R+L + +A+ + + + K
Sbjct: 541 VKLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAEADGERLRQK 600
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL----LEAQ 117
+L+Q + + QL E+A L K++ + L K E + + + LE +
Sbjct: 601 KELDQVISERDILGSQLVRRNDELALLYEKIKIQQSVLNKGESQYNQRLEDMRILRLEIK 660
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKE 150
+ E + + + N + +E LKE
Sbjct: 661 KLRREKGILARSMANVEELRQEFFHMQRELLKE 693
Score = 38.3 bits (85), Expect = 0.030
Identities = 45/226 (19%), Positives = 93/226 (41%), Gaps = 9/226 (3%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ--VEEDLIL 59
+ I KK+ + +K +T + Q E ++ EL +K + E IL
Sbjct: 331 EQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQA-ELDRKAMDELLRERDIL 389
Query: 60 NKNKLEQANK-----DLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 113
NKN L+ N DL + +Q E E+ + Q+ + + E+ +
Sbjct: 390 NKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQA 449
Query: 114 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 173
+ Q N KV E + +++ + +LK+ + L E + S+ L +
Sbjct: 450 SDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVEAQ 509
Query: 174 DELEVAEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVE 219
DE+ + ++K ++ EL+E++ ++L L + +++ + E
Sbjct: 510 DEITDMKRKLKIMIHQVDELKEDISAKESALVKLHLEQQRIEKEKE 555
Score = 38.3 bits (85), Expect = 0.030
Identities = 38/227 (16%), Positives = 102/227 (44%), Gaps = 7/227 (3%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++A KK+ + + D + + D + A +K + V+ ++ +E ++
Sbjct: 365 VEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNY 424
Query: 61 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 120
K++ ++ K + EK+ + + L +KV ED++ E + ++K+ E++
Sbjct: 425 KDEAQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKL 484
Query: 121 DENNRMCKVLEN----RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK-LAFVEDE 175
+ + + + + ++ E D++T+ ++ +++ D +++S K A V+
Sbjct: 485 KQQQNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESALVKLH 544
Query: 176 LEV--AEDRVKSGDAKISELEEELKVVGNSLKSLEVSEEKANQRVEE 220
LE E ++ A++ +L ++ + ++ E E K + + E
Sbjct: 545 LEQQRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAE 591
Score = 35.9 bits (79), Expect = 0.16
Identities = 40/202 (19%), Positives = 99/202 (49%), Gaps = 26/202 (12%)
Query: 11 MKLEKDNAMDKADTCEQQARDANL--RAEKVNEEVRELQKKLAQVEE---DLILNKNKLE 65
+KL++ + +A ++ NL +++ + R+L+ + QV+E D+ ++ L
Sbjct: 482 IKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESALV 541
Query: 66 QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNR 125
+ + + + EK+ +AE+ L ++ + + +EK E ++KLL AD
Sbjct: 542 KLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQE----AEERKLLRIIAEAD---- 593
Query: 126 MCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 185
R +Q +E +DQ+ + E +L ++DE LA + +++++ + +
Sbjct: 594 -----GERLRQKKE-LDQV---ISERDILGSQLVRRNDE----LALLYEKIKIQQSVLNK 640
Query: 186 GDAKISELEEELKVVGNSLKSL 207
G+++ ++ E+++++ +K L
Sbjct: 641 GESQYNQRLEDMRILRLEIKKL 662
>AK093285-1|BAC04121.1| 797|Homo sapiens protein ( Homo sapiens
cDNA FLJ35966 fis, clone TESTI2012628, moderately
similar to Mus musculus STAP mRNA for sperm tail
associated protein. ).
Length = 797
Score = 55.2 bits (127), Expect = 2e-07
Identities = 49/212 (23%), Positives = 99/212 (46%), Gaps = 8/212 (3%)
Query: 5 KKKMQAMKLE---KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLA-----QVEED 56
K++ A +LE K+ DK+ E +A A ++ K + E + Q++LA Q +E+
Sbjct: 433 KQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQERLAAQQAAQCKEE 492
Query: 57 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 116
L LE + L++ Q T T+ AL+RK ++DL ++ E+ +
Sbjct: 493 AALAGCHLEDTQRKLQKHYLQTTITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSL 552
Query: 117 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 176
QQS + LE EERM +L +L++ R ++++ + +KL + ++
Sbjct: 553 QQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQV 612
Query: 177 EVAEDRVKSGDAKISELEEELKVVGNSLKSLE 208
+ + ++ ++ EE+L+ + +L+
Sbjct: 613 LQWQKQHQNDLKMLAAKEEQLREFQEEMAALK 644
Score = 47.2 bits (107), Expect = 7e-05
Identities = 36/210 (17%), Positives = 95/210 (45%), Gaps = 4/210 (1%)
Query: 4 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 63
IKK ++ ++ +KD+ + + +D + E V+E+ R + K + ++E DL
Sbjct: 304 IKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSEQKRNIMKDMMKLELDL---HGL 360
Query: 64 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 123
E+ + +E K+K +T + + L + + ++ K ++ + L E ++ +
Sbjct: 361 REETSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQV 420
Query: 124 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 183
E ++ + +L +KEA+ + + + + ++ +++ LE A+ +
Sbjct: 421 QNSLLKKEKELEKQQCMATELEMTVKEAK-QDKSKEAECKALQAEVQKLKNSLEEAKQQE 479
Query: 184 KSGDAKISELEEELKVVGNSLKSLEVSEEK 213
+ + ++ +EE + G L+ + +K
Sbjct: 480 RLAAQQAAQCKEEAALAGCHLEDTQRKLQK 509
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/139 (19%), Positives = 69/139 (49%), Gaps = 8/139 (5%)
Query: 2 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 61
DA+ +K A + + A++K + + + + + + + Q+K AQ+EE++I +
Sbjct: 522 DALSRKSAACQDDLTQALEKLNHVTSETKS-------LQQSLTQTQEKKAQLEEEIIAYE 574
Query: 62 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE-EDLEKSEERSGTAQQKLLEAQQSA 120
++++ N +L + +E EV A ++K++++ + L+ ++ + + +Q
Sbjct: 575 ERMKKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLR 634
Query: 121 DENNRMCKVLENRAQQDEE 139
+ M + EN + D+E
Sbjct: 635 EFQEEMAALKENLLEDDKE 653
Score = 36.7 bits (81), Expect = 0.092
Identities = 28/194 (14%), Positives = 80/194 (41%)
Query: 3 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 62
A++ ++Q +K + A + QQA A + + Q+KL + + K
Sbjct: 460 ALQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHLEDTQRKLQKHYLQTTITKE 519
Query: 63 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 122
+ ++ + LT ++ + + + +++ L +++E+ +++++ ++ +
Sbjct: 520 AYDALSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKK 579
Query: 123 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 182
N + L Q+ E + +L+E + + LA E++L ++
Sbjct: 580 LNTELRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQEE 639
Query: 183 VKSGDAKISELEEE 196
+ + + E ++E
Sbjct: 640 MAALKENLLEDDKE 653
Score = 35.1 bits (77), Expect = 0.28
Identities = 39/212 (18%), Positives = 92/212 (43%), Gaps = 9/212 (4%)
Query: 1 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 60
++ + + ++++ +K E++ R +K+N E+R+L+ + E ++
Sbjct: 542 LNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQESELEVHAF 601
Query: 61 KNKLEQANKDLEEKEKQ-------LTATEAEVAALNRKVQQIEED-LEKSEERSGTAQQK 112
KLE+ + + + +KQ L A E ++ ++ ++E+ LE +E Q
Sbjct: 602 DKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQEEMAALKENLLEDDKEPCCLPQWS 661
Query: 113 L-LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 171
+ + + N+++ LE A+Q + ++L NQL+E G+ D + +
Sbjct: 662 VPKDTCRLYRGNDQIMTNLEQWAKQQKVANEKLGNQLREQVKYIAKLSGEKDHLHSVMVH 721
Query: 172 VEDELEVAEDRVKSGDAKISELEEELKVVGNS 203
++ E + + ++ K K +G S
Sbjct: 722 LQQENKKLKKEIEEKKMKAENTRLCTKALGPS 753
Score = 31.1 bits (67), Expect = 4.6
Identities = 47/288 (16%), Positives = 119/288 (41%), Gaps = 26/288 (9%)
Query: 9 QAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQAN 68
+AM D +A E+ + + ++++L+KKL ++++L + +L+ +
Sbjct: 49 EAMNSSHDKKQAQALAFEESEVEFGSSKQCHLRQLQQLKKKLLVLQQELEFHTEELQTSY 108
Query: 69 KDLEEKEKQLTATEAEVAALNR-------KVQQIEEDLEKSEERSG----TAQQKLLEAQ 117
L + + L +++ L+ +V EE++ E +G AQ++L A
Sbjct: 109 YSLRQYQSILEKQTSDLVLLHHHCKLKEDEVILYEEEMGNHNENTGEKLHLAQEQLALAG 168
Query: 118 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR-----LLAEDADGKSDEVSRKL--- 169
R + ++ Q ++ L Q+K + ++ ++ + K D ++
Sbjct: 169 DKIASLERSLNLYRDKYQSSLSNIELLECQVKMLQGELGGIMGQEPENKGDHSKVRIYTS 228
Query: 170 AFVEDELEVAEDRVKSGDAKISELEEELKVVGNSL---KSLEVSEEKANQRVEEFXXXXX 226
+ E + A+ R+ K+S+ ++ ++ + N L +L + EKA +++
Sbjct: 229 PCMIQEHQEAQKRLSEVWQKVSQQDDLIQELRNKLACSNALVLEREKALIKLQ----ADF 284
Query: 227 XXXXXXXXXXXXXXXXXKTVKKLQKEVDRLEDELGINKDRYKSLADEM 274
+ +KK+ K + +D ++ + Y++L ++
Sbjct: 285 ASCTATHRYPPSSSEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDL 332
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.303 0.121 0.298
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 28,782,131
Number of Sequences: 224733
Number of extensions: 1167281
Number of successful extensions: 34043
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 1687
Number of HSP's successfully gapped in prelim test: 2113
Number of HSP's that attempted gapping in prelim test: 10942
Number of HSP's gapped (non-prelim): 15398
length of query: 284
length of database: 73,234,838
effective HSP length: 89
effective length of query: 195
effective length of database: 53,233,601
effective search space: 10380552195
effective search space used: 10380552195
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 43 (21.8 bits)
S2: 65 (30.3 bits)
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