Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001570-TA|BGIBMGA001570-PA|IPR000842|Phosphoribosyl
pyrophosphate synthetase, IPR005946|Ribose-phosphate
pyrophosphokinase, IPR000836|Phosphoribosyltransferase
(318 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P60891 Cluster: Ribose-phosphate pyrophosphokinase 1; n... 505 e-142
UniRef50_Q9VT33 Cluster: Ribose-phosphate pyrophosphokinase; n=4... 497 e-139
UniRef50_UPI000156094F Cluster: PREDICTED: similar to PRPS2 prot... 451 e-125
UniRef50_Q4P1D3 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 378 e-104
UniRef50_A7M6E2 Cluster: Ribose-phosphate pyrophosphokinase I; n... 323 3e-87
UniRef50_Q75JN8 Cluster: Similar to ribose-phosphate pyrophospho... 314 3e-84
UniRef50_UPI00015B404E Cluster: PREDICTED: similar to ENSANGP000... 300 3e-80
UniRef50_Q8R753 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 294 2e-78
UniRef50_UPI0000EB04C8 Cluster: UPI0000EB04C8 related cluster; n... 292 9e-78
UniRef50_Q89DJ1 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 283 3e-75
UniRef50_Q42581 Cluster: Ribose-phosphate pyrophosphokinase 1; n... 280 4e-74
UniRef50_UPI00005A2C8C Cluster: PREDICTED: similar to Ribose-pho... 276 6e-73
UniRef50_A3ZLP4 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 274 2e-72
UniRef50_Q88Z84 Cluster: Ribose-phosphate pyrophosphokinase 1; n... 273 4e-72
UniRef50_Q9U465 Cluster: Phosphoribosylpyrophosphate synthetase;... 272 8e-72
UniRef50_A4T068 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 270 3e-71
UniRef50_Q5KCA3 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 266 7e-70
UniRef50_Q1AXL6 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 263 5e-69
UniRef50_P65239 Cluster: Ribose-phosphate pyrophosphokinase 1; n... 260 4e-68
UniRef50_Q1GEV9 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 259 6e-68
UniRef50_A0VM43 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 258 2e-67
UniRef50_Q4P9A7 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 258 2e-67
UniRef50_Q83GR1 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 255 1e-66
UniRef50_A5V1W5 Cluster: Ribose-phosphate pyrophosphokinase; n=5... 250 3e-65
UniRef50_Q9RUD2 Cluster: Probable ribose-phosphate pyrophosphoki... 250 5e-65
UniRef50_A4VV92 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 249 6e-65
UniRef50_Q6MAT0 Cluster: Probable phosphoribosyl pyrophosphate s... 248 1e-64
UniRef50_Q7MT83 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 248 1e-64
UniRef50_A4EBQ1 Cluster: Putative uncharacterized protein; n=1; ... 248 2e-64
UniRef50_Q5A4X7 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 248 2e-64
UniRef50_A6R925 Cluster: Ribose-phosphate pyrophosphokinase I; n... 247 3e-64
UniRef50_A5URX1 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 244 2e-63
UniRef50_Q8Y9L8 Cluster: Ribose-phosphate pyrophosphokinase 2; n... 243 5e-63
UniRef50_P32895 Cluster: Ribose-phosphate pyrophosphokinase 1; n... 241 2e-62
UniRef50_A1CDQ3 Cluster: Ribose-phosphate pyrophosphokinase; n=5... 239 7e-62
UniRef50_Q4Q3Z4 Cluster: Phosphoribosylpyrophosphate synthetase,... 239 9e-62
UniRef50_Q1DW45 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 238 2e-61
UniRef50_Q8D2K5 Cluster: PrsA protein; n=1; Wigglesworthia gloss... 236 5e-61
UniRef50_Q3M5L4 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 235 1e-60
UniRef50_A7TNR7 Cluster: Putative uncharacterized protein; n=1; ... 235 1e-60
UniRef50_A0CY99 Cluster: Chromosome undetermined scaffold_31, wh... 232 1e-59
UniRef50_Q8G5P2 Cluster: Ribose-phosphate pyrophosphokinase; n=5... 231 2e-59
UniRef50_P75044 Cluster: Ribose-phosphate pyrophosphokinase; n=6... 231 2e-59
UniRef50_Q4Q0M2 Cluster: Phosphoribosylpyrophosphate synthetase,... 230 3e-59
UniRef50_A7EV32 Cluster: Putative uncharacterized protein; n=1; ... 229 7e-59
UniRef50_Q6CG51 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 227 3e-58
UniRef50_Q4QI56 Cluster: Phosphoribosylpyrophosphate synthetase;... 223 5e-57
UniRef50_Q822W0 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 223 6e-57
UniRef50_Q8EUI1 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 220 4e-56
UniRef50_Q74LT0 Cluster: Phosphoribosylpyrophosphate synthetase;... 220 4e-56
UniRef50_Q03YB5 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 215 1e-54
UniRef50_Q6F241 Cluster: Ribose-phosphate pyrophosphokinase; n=6... 213 5e-54
UniRef50_Q8X022 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 212 9e-54
UniRef50_Q0G092 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 210 4e-53
UniRef50_O62580 Cluster: Phosphoribosyl pyrophosphate synthetase... 207 3e-52
UniRef50_A0E424 Cluster: Chromosome undetermined scaffold_77, wh... 202 7e-51
UniRef50_Q9EWS0 Cluster: Putative ribose-phosphate pyrophosphoki... 200 4e-50
UniRef50_A7ARJ1 Cluster: Ribose-phosphate pyrophosphokinase, put... 199 9e-50
UniRef50_Q4UNC9 Cluster: Ribose-phosphate pyrophosphokinase; n=9... 198 1e-49
UniRef50_Q6MW31 Cluster: Related to ribose-phosphate pyrophospho... 192 8e-48
UniRef50_Q98R83 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 191 2e-47
UniRef50_A7HHV4 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 187 4e-46
UniRef50_Q9PQV0 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 187 4e-46
UniRef50_Q5GTH9 Cluster: Phosphoribosylpyrophosphate synthetase;... 186 7e-46
UniRef50_Q16GA3 Cluster: Ribose-phosphate pyrophosphokinase 1, p... 181 2e-44
UniRef50_A3LVW1 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 180 4e-44
UniRef50_O60256 Cluster: Phosphoribosyl pyrophosphate synthetase... 180 4e-44
UniRef50_Q2S5C7 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 176 7e-43
UniRef50_Q0U4M1 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 172 9e-42
UniRef50_A5DKD0 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 167 4e-40
UniRef50_Q3YQZ8 Cluster: Ribose-phosphate pyrophospho kinase; n=... 165 1e-39
UniRef50_UPI00006CD8E2 Cluster: ribose-phosphate pyrophosphokina... 165 1e-39
UniRef50_A4BQ39 Cluster: Ribose-phosphate pyrophosphokinase; n=9... 161 2e-38
UniRef50_Q2GIZ1 Cluster: Ribose-phosphate pyrophosphokinase; n=6... 158 2e-37
UniRef50_Q2GCV8 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 153 8e-36
UniRef50_A2AAG9 Cluster: Likely ortholog of H. sapiens phosphori... 150 5e-35
UniRef50_Q8KKS6 Cluster: Ribose-phosphate pyrophosphokinase prot... 145 1e-33
UniRef50_O26877 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 143 5e-33
UniRef50_Q4XQD5 Cluster: Ribose-phosphate pyrophosphokinase, put... 138 2e-31
UniRef50_O59586 Cluster: Ribose-phosphate pyrophosphokinase; n=4... 136 7e-31
UniRef50_Q8TUT6 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 136 7e-31
UniRef50_UPI00015BACA3 Cluster: ribose-phosphate pyrophosphokina... 136 9e-31
UniRef50_A3DNX0 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 135 2e-30
UniRef50_Q88JA5 Cluster: Ribose-phosphate pyrophosphokinase fami... 132 9e-30
UniRef50_O83317 Cluster: Phosphoribosyl pyrophosphate synthetase... 132 1e-29
UniRef50_Q660Y0 Cluster: Phosphoribosyl pyrophosphate synthetase... 131 2e-29
UniRef50_Q222A7 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 128 2e-28
UniRef50_A7DQD3 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 125 1e-27
UniRef50_Q58761 Cluster: Ribose-phosphate pyrophosphokinase; n=7... 121 2e-26
UniRef50_Q12265 Cluster: Probable ribose-phosphate pyrophosphoki... 121 2e-26
UniRef50_Q6Z2L5-2 Cluster: Isoform 2 of Q6Z2L5 ; n=1; Oryza sati... 121 3e-26
UniRef50_A3H7E6 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 119 1e-25
UniRef50_Q97Z86 Cluster: Ribose-phosphate pyrophosphokinase; n=5... 119 1e-25
UniRef50_A4WYL1 Cluster: Putative uncharacterized protein; n=1; ... 118 2e-25
UniRef50_A4CGY8 Cluster: Phosphoribosylpyrophosphate synthetase;... 116 6e-25
UniRef50_Q8ZU24 Cluster: Ribose-phosphate pyrophosphokinase; n=4... 115 1e-24
UniRef50_A1ZM86 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 114 2e-24
UniRef50_Q6L0L1 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 114 2e-24
UniRef50_Q8IE40 Cluster: Ribose-phosphate pyrophosphokinase, put... 112 1e-23
UniRef50_O28853 Cluster: Ribose-phosphate pyrophosphokinase 2; n... 111 2e-23
UniRef50_A0RYR1 Cluster: Phosphoribosylpyrophosphate synthetase;... 110 5e-23
UniRef50_Q0W4S8 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 108 2e-22
UniRef50_Q9HLV6 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 107 4e-22
UniRef50_Q5ZWR2 Cluster: Ribose-phosphate pyrophosphokinase; n=4... 105 2e-21
UniRef50_A2BKK7 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 104 3e-21
UniRef50_A1RWZ6 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 104 3e-21
UniRef50_Q9YAW0 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 103 6e-21
UniRef50_A1RX65 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 101 2e-20
UniRef50_Q8PUX3 Cluster: Ribose-phosphate pyrophosphokinase; n=6... 101 3e-20
UniRef50_Q9HN88 Cluster: Ribose-phosphate pyrophosphokinase; n=5... 99 1e-19
UniRef50_A3CS59 Cluster: Ribose-phosphate pyrophosphokinase; n=4... 99 2e-19
UniRef50_A7MKK1 Cluster: Putative uncharacterized protein; n=1; ... 98 3e-19
UniRef50_Q11BI1 Cluster: Ribose-phosphate pyrophosphokinase; n=4... 97 5e-19
UniRef50_Q075L4 Cluster: Plastid ribose-phosphate diphosphokinas... 95 2e-18
UniRef50_Q89QK8 Cluster: Bll3116 protein; n=5; Bradyrhizobiaceae... 95 3e-18
UniRef50_Q2SLU9 Cluster: Phosphoribosylpyrophosphate synthetase;... 94 5e-18
UniRef50_Q12E98 Cluster: Ribose-phosphate pyrophosphokinase; n=3... 91 3e-17
UniRef50_Q1GQ93 Cluster: Ribose-phosphate pyrophosphokinase; n=6... 89 2e-16
UniRef50_Q607P3 Cluster: Ribose-phosphate pyrophosphokinase fami... 87 4e-16
UniRef50_Q4DSS9 Cluster: Ribose-phosphate pyrophosphokinase, put... 87 6e-16
UniRef50_A6BI68 Cluster: Putative uncharacterized protein; n=2; ... 87 7e-16
UniRef50_A1HDW3 Cluster: Ribose-phosphate diphosphokinase; n=3; ... 86 1e-15
UniRef50_A2X0F3 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 85 2e-15
UniRef50_A4XET1 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 85 2e-15
UniRef50_O29666 Cluster: Ribose-phosphate pyrophosphokinase 1; n... 85 2e-15
UniRef50_Q97KU7 Cluster: Phosphoribosylpyrophosphate synthetase;... 85 3e-15
UniRef50_Q1FFM9 Cluster: Ribose-phosphate pyrophosphokinase; n=8... 84 4e-15
UniRef50_Q4QIB8 Cluster: Ribose-phosphate pyrophosphokinase, put... 84 5e-15
UniRef50_Q6KG64 Cluster: Putative uncharacterized protein; n=2; ... 81 4e-14
UniRef50_A3W7X1 Cluster: Phosphoribosylpyrophosphate synthetase;... 80 9e-14
UniRef50_Q21W91 Cluster: Ribose-phosphate pyrophosphokinase; n=2... 78 3e-13
UniRef50_A7B5K6 Cluster: Putative uncharacterized protein; n=1; ... 76 1e-12
UniRef50_A6DTG6 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 75 3e-12
UniRef50_A4FCC2 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 72 2e-11
UniRef50_Q7XZ65 Cluster: Phosphoribosyl pyrophosphate synthetase... 72 2e-11
UniRef50_UPI00004989B9 Cluster: ribose-phosphate pyrophosphokina... 71 3e-11
UniRef50_Q11SD6 Cluster: Phosphoribosylpyrophosphate synthetase;... 70 7e-11
UniRef50_Q93Z66 Cluster: Ribose-phosphate pyrophosphokinase 3; n... 68 3e-10
UniRef50_Q6FDK1 Cluster: Putative ribose-phosphate pyrophosphoki... 66 1e-09
UniRef50_Q8KTQ3 Cluster: Phosphoribosylpyrophosphate synthetase;... 66 1e-09
UniRef50_Q680A5 Cluster: Ribose-phosphate pyrophosphokinase 4; n... 65 3e-09
UniRef50_A6VUG9 Cluster: Ribose-phosphate pyrophosphokinase; n=4... 64 6e-09
UniRef50_A2FHP9 Cluster: Ribose-phosphate pyrophosphokinase fami... 63 8e-09
UniRef50_A6LV64 Cluster: Ribose-phosphate pyrophosphokinase; n=1... 61 3e-08
UniRef50_Q0U4M2 Cluster: Putative uncharacterized protein; n=1; ... 61 3e-08
UniRef50_Q64M76 Cluster: Phosphoribosyl pyrophosphate synthase-l... 59 1e-07
UniRef50_Q7P228 Cluster: Probable ribose-phosphate diphosphokina... 58 3e-07
UniRef50_Q4FCY7 Cluster: Phosphoribosyl pyrophosphate synthetase... 57 7e-07
UniRef50_A2FWD0 Cluster: Ribose-phosphate pyrophosphokinase fami... 56 2e-06
UniRef50_Q8EFJ2 Cluster: Phosphoribosyl transferase domain prote... 54 4e-06
UniRef50_A0CXZ2 Cluster: Chromosome undetermined scaffold_30, wh... 54 5e-06
UniRef50_A7SHY8 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 54 6e-06
UniRef50_A6MK41 Cluster: Phosphoribosyl pyrophosphate synthetase... 51 3e-05
UniRef50_P58860 Cluster: Orotate phosphoribosyltransferase; n=1;... 51 3e-05
UniRef50_A2XQT7 Cluster: Putative uncharacterized protein; n=1; ... 47 6e-04
UniRef50_Q12V34 Cluster: PyrE-like protein; n=2; Methanosarcinac... 46 0.001
UniRef50_Q9K9W3 Cluster: Orotate phosphoribosyltransferase; n=54... 45 0.003
UniRef50_O08359 Cluster: Orotate phosphoribosyltransferase; n=4;... 44 0.004
UniRef50_Q30L82 Cluster: Gp63; n=1; Listeria phage P100|Rep: Gp6... 43 0.012
UniRef50_Q3IJQ7 Cluster: Putative uncharacterized protein; n=2; ... 42 0.016
UniRef50_Q2FPQ2 Cluster: Orotate phosphoribosyltransferase; n=4;... 42 0.016
UniRef50_A4TUN0 Cluster: Orotate phosphoribosyltransferase; n=1;... 42 0.028
UniRef50_A2BJ25 Cluster: Orotate phosphoribosyltransferase; n=1;... 41 0.037
UniRef50_O58855 Cluster: Orotate phosphoribosyltransferase; n=3;... 41 0.048
UniRef50_Q9HM15 Cluster: Orotate phosphoribosyltransferase; n=3;... 40 0.064
UniRef50_A7HHY1 Cluster: Phosphoribosyltransferase; n=2; Anaerom... 40 0.11
UniRef50_Q8PVD0 Cluster: PyrE-like protein; n=5; Methanosarcinal... 39 0.15
UniRef50_A1ZTS6 Cluster: Orotate phosphoribosyltransferase; n=1;... 38 0.26
UniRef50_A0UWY5 Cluster: Phosphoribosyltransferase; n=1; Clostri... 38 0.34
UniRef50_P46534 Cluster: Orotate phosphoribosyltransferase; n=6;... 38 0.34
UniRef50_Q04H27 Cluster: Orotate phosphoribosyltransferase; n=1;... 38 0.45
UniRef50_Q18CV9 Cluster: Amidophosphoribosyltransferase; n=1; Cl... 37 0.60
UniRef50_UPI0000D57455 Cluster: PREDICTED: similar to CG3830-PA;... 36 1.4
UniRef50_Q9V2H4 Cluster: Hypoxanthine guanine phosphoribosyltran... 36 1.4
UniRef50_Q9Y9D8 Cluster: Orotate phosphoribosyltransferase; n=1;... 36 1.4
UniRef50_Q3XYF1 Cluster: Orotate phosphoribosyl transferase; n=3... 36 1.8
UniRef50_Q9HS16 Cluster: PyrE-like protein; n=4; Halobacteriacea... 36 1.8
UniRef50_Q9KFN4 Cluster: ABC transporter; n=22; Firmicutes|Rep: ... 35 2.4
UniRef50_Q7UQ46 Cluster: Hypoxanthine-guanine phosphoribosyltran... 35 2.4
UniRef50_Q0ID76 Cluster: PyrF/pyrE bifunctional enzyme; n=5; Syn... 35 2.4
UniRef50_A0Y8V6 Cluster: Competence protein ComF, putative; n=1;... 35 2.4
UniRef50_Q8RCE2 Cluster: Predicted amidophosphoribosyltransferas... 35 3.2
UniRef50_Q89VW6 Cluster: Blr0929 protein; n=5; Bradyrhizobium|Re... 35 3.2
UniRef50_Q0KT47 Cluster: Putative uncharacterized protein; n=1; ... 35 3.2
UniRef50_Q5CX92 Cluster: YbiN-like RNA methylase; n=3; Cryptospo... 35 3.2
UniRef50_Q45918 Cluster: Orotate phosphoribosyltransferase; n=2;... 35 3.2
UniRef50_Q314R1 Cluster: ComF family protein; n=1; Desulfovibrio... 34 4.2
UniRef50_Q2S305 Cluster: Orotate phosphoribosyltransferase; n=1;... 34 4.2
UniRef50_Q04EC9 Cluster: Predicted amidophosphoribosyltransferas... 34 4.2
UniRef50_A2U7L3 Cluster: Late competence protein; n=1; Bacillus ... 34 4.2
UniRef50_A2G5Q2 Cluster: Putative uncharacterized protein; n=1; ... 34 4.2
UniRef50_Q8YSY4 Cluster: Bifunctional enzyme pyrF/pyrE [Includes... 34 4.2
UniRef50_Q41CE1 Cluster: Late competence protein; n=1; Exiguobac... 34 5.6
UniRef50_A6CB14 Cluster: Putative uncharacterized protein; n=1; ... 34 5.6
UniRef50_Q9NF11 Cluster: Putative uncharacterized protein; n=2; ... 34 5.6
UniRef50_Q8SR76 Cluster: T COMPLEX PROTEIN 1 GAMMA SUBUNIT; n=1;... 34 5.6
UniRef50_A6GFD2 Cluster: Cytochrome P450; n=1; Plesiocystis paci... 33 7.3
UniRef50_A4XK15 Cluster: Phosphoribosyltransferase; n=1; Caldice... 33 7.3
UniRef50_Q9P8F6 Cluster: Cephalosporin C regulator 1; n=1; Acrem... 33 7.3
UniRef50_Q6ABA4 Cluster: Putative uncharacterized protein; n=1; ... 33 9.7
UniRef50_Q67M40 Cluster: Conserved domain protein; n=1; Symbioba... 33 9.7
UniRef50_Q0LJ69 Cluster: Aldehyde dehydrogenase; n=1; Herpetosip... 33 9.7
UniRef50_A7N438 Cluster: Putative uncharacterized protein; n=1; ... 33 9.7
UniRef50_A4FCI4 Cluster: Phosphoribosyltransferase; n=1; Sacchar... 33 9.7
UniRef50_A3DJU7 Cluster: Methyl-accepting chemotaxis sensory tra... 33 9.7
UniRef50_A3DHM1 Cluster: Phosphoribosyltransferase; n=1; Clostri... 33 9.7
UniRef50_A7D3I4 Cluster: Phosphoribosyltransferase; n=1; Halorub... 33 9.7
UniRef50_O27888 Cluster: Orotate phosphoribosyltransferase; n=2;... 33 9.7
>UniRef50_P60891 Cluster: Ribose-phosphate pyrophosphokinase 1;
n=156; Eukaryota|Rep: Ribose-phosphate pyrophosphokinase
1 - Homo sapiens (Human)
Length = 318
Score = 505 bits (1246), Expect = e-142
Identities = 234/317 (73%), Positives = 278/317 (87%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGC 60
MPNIK+F+GSSH D+++ I RLGL LG+ TKKFSN+ET VEIGESVRGEDVYIVQSGC
Sbjct: 1 MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGC 60
Query: 61 GEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAG 120
GEINDNLMEL IMINACKIASASRVTAV+PCFPY+RQDKK+KSRAPI+AKL+AN++SVAG
Sbjct: 61 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAG 120
Query: 121 ADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTG 180
ADH+IT+DLHASQIQGFF+IPVDNLYAEPA+ KWI+ENI EW++ +VSPDAGG KR+T
Sbjct: 121 ADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTS 180
Query: 181 IADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAG 240
IADRL++DFA+IHKER++ANE D VLVGDVK++ AI+VDD+ADTC TI A+ L AG
Sbjct: 181 IADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAG 240
Query: 241 ANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAI 300
A ++YA LTHGIF+G AI +INN+ EA+VVTNTIPQE MK C K+Q IDIS++LAEAI
Sbjct: 241 ATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAI 300
Query: 301 RRTHYAESVSYLFTNVP 317
RRTH ESVSYLF++VP
Sbjct: 301 RRTHNGESVSYLFSHVP 317
>UniRef50_Q9VT33 Cluster: Ribose-phosphate pyrophosphokinase; n=4;
Fungi/Metazoa group|Rep: Ribose-phosphate
pyrophosphokinase - Drosophila melanogaster (Fruit fly)
Length = 388
Score = 497 bits (1226), Expect = e-139
Identities = 240/341 (70%), Positives = 286/341 (83%), Gaps = 23/341 (6%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGC 60
MPNIKVF+G+SHPD+A+ IV RLG++LG+ TKKFSN ET VEIGESVRGEDVYIVQSG
Sbjct: 48 MPNIKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGS 107
Query: 61 GEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEK------------------ 102
GEINDNLMEL IMINACKIASASRVTAV+PCFPY+RQDKK+K
Sbjct: 108 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKLAGSEDNAESKKLAKKNY 167
Query: 103 -----SRAPITAKLLANLISVAGADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKE 157
SRAPI+AKL+AN++SVAGADH+IT+DLHASQIQGFF+IPVDNLYAEPA+ KWIKE
Sbjct: 168 DWKFRSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKE 227
Query: 158 NIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAI 217
NIPEWK+S++VSPDAGG KR+T IADRL+++FA+IHKER++ANE S VLVGDVK+K AI
Sbjct: 228 NIPEWKNSIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDKIAI 287
Query: 218 MVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQ 277
+VDD+ADTC TI+ A+ L EAGA K+YA LTHGIF+G AI +INN+ EA+VVTNTIPQ
Sbjct: 288 LVDDMADTCGTIVHAADRLVEAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQ 347
Query: 278 EKNMKLCPKLQTIDISVMLAEAIRRTHYAESVSYLFTNVPY 318
+ +M+ CPK+Q ID+S+M AEA+RRTH ESVSYLF+NVPY
Sbjct: 348 DGHMRDCPKIQCIDVSMMFAEAVRRTHNGESVSYLFSNVPY 388
>UniRef50_UPI000156094F Cluster: PREDICTED: similar to PRPS2
protein; n=2; Mammalia|Rep: PREDICTED: similar to PRPS2
protein - Equus caballus
Length = 301
Score = 451 bits (1111), Expect = e-125
Identities = 207/281 (73%), Positives = 250/281 (88%)
Query: 37 NKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMINACKIASASRVTAVVPCFPYSR 96
N +T VEIGESVRGEDVYI+QSGCGEINDNLMEL IMINACKIAS+SRVTAV+PCFPY+R
Sbjct: 20 NGKTLVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIPCFPYAR 79
Query: 97 QDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIK 156
QDKK+KSRAPI+AKL+AN++SVAGADH+IT+DLHASQIQGFF+IPVDNLYAEPA+ +WI+
Sbjct: 80 QDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIR 139
Query: 157 ENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTA 216
ENI +WK+ ++VSPDAGG KR+T IADRL++DFA+IHKER++ANE D VLVGDVK++ A
Sbjct: 140 ENIAQWKNCIIVSPDAGGAKRVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVA 199
Query: 217 IMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIP 276
I+VDD+ADTC TI A+ L AGA K+YA LTHGIF+G AI +INN++ EA+VVTNTIP
Sbjct: 200 ILVDDMADTCGTICHAADKLLSAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIP 259
Query: 277 QEKNMKLCPKLQTIDISVMLAEAIRRTHYAESVSYLFTNVP 317
QE M+ C K+Q IDIS++LAEAIRRTH ESVSYLF++VP
Sbjct: 260 QEDKMRHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVP 300
>UniRef50_Q4P1D3 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Ustilago maydis|Rep: Ribose-phosphate pyrophosphokinase
- Ustilago maydis (Smut fungus)
Length = 432
Score = 378 bits (931), Expect = e-104
Identities = 185/324 (57%), Positives = 241/324 (74%), Gaps = 10/324 (3%)
Query: 4 IKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGC--- 60
IKVF+G+SHP++A+ I RLG LG+AT + + E+ V I ESVR DVYI+ + C
Sbjct: 8 IKVFSGTSHPELAELIAKRLGQPLGKATVTRNESGESIVRIAESVREHDVYIINTSCVSP 67
Query: 61 ------GEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLAN 114
N +LMEL IMI+ACK ASA R+TAV+P F Y+RQDKK+KSRAPITAKL+AN
Sbjct: 68 TPTGAAASPNTSLMELLIMIHACKTASAKRITAVIPHFFYARQDKKDKSRAPITAKLIAN 127
Query: 115 LISVAGADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGG 174
++ AG DHVIT+DLHASQIQGFF++PVDNLYAEPA ++I+E + + +V+VSPDAGG
Sbjct: 128 MLENAGCDHVITMDLHASQIQGFFDVPVDNLYAEPAALQYIREMV-DVNKAVIVSPDAGG 186
Query: 175 VKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAE 234
KR T +ADRL++DFA+ HKER+RANE VLVG+V+ K AI+VDD+ADTC T+ A
Sbjct: 187 AKRATSLADRLELDFALFHKERKRANEVSRMVLVGNVEGKVAILVDDMADTCGTLELAAS 246
Query: 235 ALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISV 294
L E GA ++ A +THGI +G A+++I+NS LE ++VTNT+PQ N C K++ IDIS
Sbjct: 247 QLIEYGAERVLAIVTHGILSGPALDRISNSRLEKLIVTNTLPQSHNRSRCTKIEEIDISH 306
Query: 295 MLAEAIRRTHYAESVSYLFTNVPY 318
+LAE IRR+HY ESVS LF +PY
Sbjct: 307 VLAETIRRSHYGESVSVLFNQIPY 330
>UniRef50_A7M6E2 Cluster: Ribose-phosphate pyrophosphokinase I; n=1;
Dugesia ryukyuensis|Rep: Ribose-phosphate
pyrophosphokinase I - Dugesia ryukyuensis
Length = 316
Score = 323 bits (794), Expect = 3e-87
Identities = 152/316 (48%), Positives = 228/316 (72%), Gaps = 2/316 (0%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGC 60
M NI++F+GSS+ + + I R+G+ L A KFSN ET+V+I ESVRG+DV+I+QSG
Sbjct: 1 MLNIRLFSGSSNILLTEKIGERIGIKLSEAILNKFSNNETSVQIKESVRGKDVFILQSGY 60
Query: 61 GEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAG 120
++N++LMEL IMINACK AS++R+TAV+P PYSRQ KK+ +R PITAKL+A+L+ +AG
Sbjct: 61 IDVNNHLMELLIMINACKNASSARITAVLPYMPYSRQSKKDNNRVPITAKLVADLLHIAG 120
Query: 121 ADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTG 180
A+H+IT+DLHASQIQGFFN+PVDNL +E WIK+NI +W+ + S + +R+
Sbjct: 121 ANHIITMDLHASQIQGFFNVPVDNLLSESCHISWIKKNISKWEEITIFSLNVTSAERVAN 180
Query: 181 IADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAG 240
+A+ L + F +I+ E++ A+E +LVGDV ++ A+++ D+ D CD ++ + L+E G
Sbjct: 181 MANTLKVRFGLIYVEKKEASE--QIILVGDVVSRIAVILLDIIDNCDLVISSVKRLKEVG 238
Query: 241 ANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAI 300
A +Y THG+ + ++++++S + +VVTNTI QEK +K K+ +D+SV+ AEAI
Sbjct: 239 AAGVYVIATHGMLSERLMKEVDDSIITKLVVTNTICQEKYVKQSDKIACLDVSVIFAEAI 298
Query: 301 RRTHYAESVSYLFTNV 316
RR HY ESVS L+ N+
Sbjct: 299 RRIHYGESVSCLYNNL 314
>UniRef50_Q75JN8 Cluster: Similar to ribose-phosphate
pyrophosphokinase; n=3; Dictyostelium discoideum|Rep:
Similar to ribose-phosphate pyrophosphokinase -
Dictyostelium discoideum (Slime mold)
Length = 329
Score = 314 bits (770), Expect = 3e-84
Identities = 158/318 (49%), Positives = 221/318 (69%), Gaps = 13/318 (4%)
Query: 6 VFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCG-EIN 64
+ G++HP ++K I + L +G A KF+N ET V I ESVR D+YIVQ C +N
Sbjct: 8 ILHGNAHPKLSKEIASCLNTEVGNALVSKFANSETQVIINESVRDVDLYIVQPTCNPSVN 67
Query: 65 DNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHV 124
D LMEL +M++ K ASA R+TAVVP F Y+RQ KK+KSRAPIT KL+AN++ AG D V
Sbjct: 68 DYLMELLVMVDGAKRASAHRITAVVPFFGYARQSKKDKSRAPITCKLVANMMEAAGIDRV 127
Query: 125 ITIDLHASQIQGFFNIPVDNLYAEPAITKWI-KENIPEW--KSSVMVSPDAGGVKRMTGI 181
IT+DLH+SQIQGFFNIPV+N+Y EP K+I K+ E+ + V+VSP GGVKR I
Sbjct: 128 ITMDLHSSQIQGFFNIPVENVYTEPLFVKYIKKKKKTEFLNQEFVIVSPGVGGVKRAKAI 187
Query: 182 ADRLDIDFAIIHKERQRAN---------EGDSTVLVGDVKNKTAIMVDDLADTCDTILKG 232
+D+L+ + AIIH+ + + + + TVLVGDV K AI++DD+ADTC T+
Sbjct: 188 SDKLESELAIIHRANKEMSLSLSSSFSFDIEETVLVGDVTGKIAIIIDDIADTCKTLKLA 247
Query: 233 AEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDI 292
++AL + GA K+YA +THG+F+ NAI+ IN+SS+ +V+T++IP E N + CPKL+ I I
Sbjct: 248 SKALIKKGAIKVYALVTHGVFSNNAIDIINDSSITELVITDSIPNEHNKEKCPKLKIISI 307
Query: 293 SVMLAEAIRRTHYAESVS 310
+ +L+E +RR H+ ESV+
Sbjct: 308 ASVLSETMRRCHHGESVT 325
>UniRef50_UPI00015B404E Cluster: PREDICTED: similar to
ENSANGP00000018618; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000018618 - Nasonia
vitripennis
Length = 322
Score = 300 bits (736), Expect = 3e-80
Identities = 147/314 (46%), Positives = 211/314 (67%), Gaps = 3/314 (0%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGE 62
+I + G+SHP++A I RLG+ G +N+ET VEIG+SVRG+D+YI+Q+G +
Sbjct: 8 DIVIIAGNSHPELASLIADRLGVKNGGCAVYYKTNRETMVEIGDSVRGKDIYIIQTGTKD 67
Query: 63 INDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGAD 122
+N+N+MEL IM ACK +SA + VVP PYS+Q K K R I +KLLA ++ +G
Sbjct: 68 VNNNIMELLIMAYACKTSSAKSIVGVVPYLPYSKQCKMRK-RGCIVSKLLAKMMCKSGLT 126
Query: 123 HVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIA 182
H+IT+DLH +IQGFF+ PVDNL A P + ++I+E+IP++++SV+V+ + G K+ T A
Sbjct: 127 HLITMDLHQKEIQGFFDCPVDNLRASPFLLQYIQESIPDFRNSVIVARNPGSAKKATSYA 186
Query: 183 DRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGAN 242
+RL + A+IH E+ + E +VGDV + AIMVDD+ D + + AE L+E GA
Sbjct: 187 ERLRLGIAVIHGEQPK--EKPPINVVGDVGGRIAIMVDDMVDDVQSFVAAAEVLKERGAY 244
Query: 243 KIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRR 302
KIY THG+ + +A I S ++ +VVTNTIP E C K++T+DIS++LAEAIRR
Sbjct: 245 KIYVLATHGLLSSDAPRLIEESPIDEVVVTNTIPHELQKMQCHKIKTVDISILLAEAIRR 304
Query: 303 THYAESVSYLFTNV 316
H ES+SYLF NV
Sbjct: 305 IHNKESMSYLFKNV 318
>UniRef50_Q8R753 Cluster: Ribose-phosphate pyrophosphokinase; n=18;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Thermoanaerobacter tengcongensis
Length = 316
Score = 294 bits (722), Expect = 2e-78
Identities = 149/312 (47%), Positives = 211/312 (67%), Gaps = 2/312 (0%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGE 62
++K+FTG+S+P +A I LGL L + FS+ E +V IGESVRG V+++QS C
Sbjct: 7 SLKIFTGNSNPKLASEIAEHLGLKLADSEVGTFSDGEISVRIGESVRGASVFVIQSTCAP 66
Query: 63 INDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGAD 122
+N+NLMEL IMI+A K ASA+ + AV+P + Y+RQD+K K+R PITAKL+A+LI+ AGA
Sbjct: 67 VNNNLMELLIMIDAFKRASAAEINAVIPYYGYARQDRKAKARDPITAKLVADLITAAGAH 126
Query: 123 HVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIA 182
V+T+DLHA QIQG+FNIPVD+L P + K+ + V+VSPD G V R A
Sbjct: 127 RVVTMDLHAPQIQGYFNIPVDHLLGGPILAKYFMDK-ELGDDVVVVSPDHGSVTRARYFA 185
Query: 183 DRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGAN 242
++L+ AII K R +AN + ++GDVK K AI+VDDL DT T+++ AEAL + GA
Sbjct: 186 EKLNAPLAIIDKRRPKANVAEVMNIIGDVKGKKAILVDDLIDTAGTLVQAAEALLDHGAV 245
Query: 243 KIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRR 302
+IYA THG+ +G AIE++ S ++ +V+T+TIP + K+ K++ ++ + AEAI R
Sbjct: 246 EIYACATHGVLSGPAIERLKESPIKEVVITDTIPLPEEKKI-DKIKVRSVAPLFAEAILR 304
Query: 303 THYAESVSYLFT 314
H SVS LFT
Sbjct: 305 IHEGMSVSKLFT 316
>UniRef50_UPI0000EB04C8 Cluster: UPI0000EB04C8 related cluster; n=1;
Canis lupus familiaris|Rep: UPI0000EB04C8 UniRef100
entry - Canis familiaris
Length = 298
Score = 292 bits (716), Expect = 9e-78
Identities = 158/318 (49%), Positives = 222/318 (69%), Gaps = 24/318 (7%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARL-GLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSG 59
+P+I +F+ S H D+++ +A L L L + TKKFSN+ET++E+ + +G+DVY +QSG
Sbjct: 1 VPDIMLFSSSLHQDLSQQDLADLMSLELSKVVTKKFSNQETSLEVSGNRKGKDVYNIQSG 60
Query: 60 CGEINDNLMELFIMINACKIASASRVTAVVPCFPYS-RQDKKEKSRAPITAKLLANLISV 118
GEI +NLM LFIMIN KI ++SRVT+V+PCFPYS + DKK+KS A I+AK +AN++
Sbjct: 61 YGEIKNNLMGLFIMINTDKITASSRVTSVIPCFPYSDKMDKKDKSHALISAKPVANML-- 118
Query: 119 AGADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRM 178
AGADH+IT+DLH SQ+QGFFNIPVDNL EPAI ENI +W++ +++
Sbjct: 119 AGADHIITMDLHDSQVQGFFNIPVDNLSVEPAIL----ENIAKWRNCIII---------Y 165
Query: 179 TGIADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALRE 238
ADR++++F+ IHKER++ANE D VLV +K+ AI+++D+AD C T
Sbjct: 166 LITADRVNMEFSFIHKERKKANEVDWMVLVSGMKDHMAILMEDMADMCST------TCHA 219
Query: 239 AGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAE 298
AGA K YA LTHGIF+G A ++ N++ EA VVT++I Q M+ C K+Q IDI ++LA+
Sbjct: 220 AGATKAYAILTHGIFSGPATSRM-NAAFEAGVVTDSILQGDKMRHCSKIQVIDILMILAK 278
Query: 299 AIRRTHYAESVSYLFTNV 316
AI R H ESV YLF+ +
Sbjct: 279 AIPRKHNGESVFYLFSYI 296
>UniRef50_Q89DJ1 Cluster: Ribose-phosphate pyrophosphokinase; n=310;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Bradyrhizobium japonicum
Length = 317
Score = 283 bits (695), Expect = 3e-75
Identities = 139/311 (44%), Positives = 210/311 (67%), Gaps = 1/311 (0%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGE 62
+IK+ G+S+P +A+ I L L L +A ++F++ E VEI E+VRG D +I+QS
Sbjct: 7 SIKLVAGNSNPALAQAIAQGLHLPLTKAVVRRFADMEIFVEIQENVRGSDAFIIQSTSFP 66
Query: 63 INDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGAD 122
ND+LMEL I+ +A + +SA R+TAV+P F Y+RQD+K SR PI+AKL+ANLI+ AG D
Sbjct: 67 ANDHLMELLIITDALRRSSARRITAVLPYFGYARQDRKSGSRTPISAKLVANLITQAGVD 126
Query: 123 HVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIA 182
V+T+DLHA QIQGFF+IP DNLYA P + + IK+ + ++++SPD GGV R G+A
Sbjct: 127 RVMTLDLHAGQIQGFFDIPTDNLYAAPLMVRDIKDKF-DLSKTMVISPDVGGVARARGLA 185
Query: 183 DRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGAN 242
R++ AI+ K R+R E + ++GDV T I+VDD+ D+ T++ A+AL GA
Sbjct: 186 KRINTPLAIVDKRRERPGESEVMNVIGDVAGYTCILVDDIVDSGGTLVNAADALIAKGAK 245
Query: 243 KIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRR 302
+YA++THG+ +G A +I NS L+ +V+T++I + P ++T+ I+ ++++AI R
Sbjct: 246 DVYAYITHGVLSGGAAARITNSKLKELVITDSILPTDAVSKAPNIRTLPIASLISDAIAR 305
Query: 303 THYAESVSYLF 313
T ESVS LF
Sbjct: 306 TAAEESVSSLF 316
>UniRef50_Q42581 Cluster: Ribose-phosphate pyrophosphokinase 1;
n=145; cellular organisms|Rep: Ribose-phosphate
pyrophosphokinase 1 - Arabidopsis thaliana (Mouse-ear
cress)
Length = 403
Score = 280 bits (686), Expect = 4e-74
Identities = 143/313 (45%), Positives = 209/313 (66%), Gaps = 6/313 (1%)
Query: 4 IKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEI 63
+K+F+G+++P +A+ I +GL+LG+ K+F++ E V++ ESVRG DVY+VQ C
Sbjct: 93 LKLFSGTANPALAQEIAWYMGLDLGKVNIKRFADGEIYVQLQESVRGCDVYLVQPTCTPT 152
Query: 64 NDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADH 123
N+NLMEL IM++AC+ ASA +VTAV+P F Y+R D+K + R I AKL+ANLI+ AGAD
Sbjct: 153 NENLMELLIMVDACRRASAKKVTAVIPYFGYARADRKTQGRESIAAKLVANLITEAGADR 212
Query: 124 VITIDLHASQIQGFFNIPVDNLYAEPAITKWI-KENIPEWKSSVMVSPDAGGVKRMTGIA 182
V+ DLH+ Q G+F+IPVD++Y +P I ++ ++IP + V+VSPD GGV R A
Sbjct: 213 VLACDLHSGQSMGYFDIPVDHVYCQPVILDYLASKSIPS-EDLVVVSPDVGGVARARAFA 271
Query: 183 DRL-DIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGA 241
+L D AI+ K R N + L+GDV+ K AIMVDD+ DT TI+KGA L + GA
Sbjct: 272 KKLSDAPLAIVDKRRSGHNVAEVMNLIGDVRGKVAIMVDDMIDTAGTIVKGAALLHQEGA 331
Query: 242 NKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIP-QEKNMKLCPKLQTIDISVMLAEAI 300
++YA TH +F+ AIE+++ L+ ++VTNT+P EKN P+L + ++ +L E I
Sbjct: 332 REVYACCTHAVFSPPAIERLSGGLLQEVIVTNTLPVAEKN--YFPQLTILSVANLLGETI 389
Query: 301 RRTHYAESVSYLF 313
R H SVS +F
Sbjct: 390 WRVHDDSSVSSIF 402
>UniRef50_UPI00005A2C8C Cluster: PREDICTED: similar to
Ribose-phosphate pyrophosphokinase I (Phosphoribosyl
pyrophosphate synthetase I) (PRS-I); n=1; Canis lupus
familiaris|Rep: PREDICTED: similar to Ribose-phosphate
pyrophosphokinase I (Phosphoribosyl pyrophosphate
synthetase I) (PRS-I) - Canis familiaris
Length = 339
Score = 276 bits (676), Expect = 6e-73
Identities = 154/310 (49%), Positives = 199/310 (64%), Gaps = 35/310 (11%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGC 60
MP+IK+F GSSH D+++ I LGL L R TKKFS++ET VE+G+S RGED Y VQSGC
Sbjct: 43 MPDIKIFGGSSHQDLSQEIAHHLGLELCRLVTKKFSDQETCVEMGKSERGEDNYTVQSGC 102
Query: 61 GEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAG 120
G +D LMEL IMIN CKIASA VTAV+PCFPY+RQ KK+KSR
Sbjct: 103 GHTSDGLMELLIMINTCKIASAHWVTAVIPCFPYARQGKKDKSRG--------------- 147
Query: 121 ADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPD--AGGVKRM 178
+DLH SQIQGFF+IPVD++ AEPA+ K I+E+I EW++ +VSPD G KR+
Sbjct: 148 ---FTCLDLHTSQIQGFFDIPVDHVRAEPAVLKCIRESISEWRNCTVVSPDRCPWGAKRV 204
Query: 179 TGIADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALRE 238
T DRL++DFA+IHKE+++AN D + N + + + T
Sbjct: 205 TSFTDRLNVDFALIHKEQKKANNMDFR-----LTNFSQLEPPEFTHGNLT---------- 249
Query: 239 AGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAE 298
+ + LTHGI +G AI +IN++ EA+VV N PQE+ MK C K+Q IDIS++LAE
Sbjct: 250 QWSTLTHRILTHGISSGPAIPRINSACFEAVVVMNITPQEEKMKHCSKIQVIDISMILAE 309
Query: 299 AIRRTHYAES 308
AIRRTH ES
Sbjct: 310 AIRRTHNGES 319
>UniRef50_A3ZLP4 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Blastopirellula marina DSM 3645
Length = 328
Score = 274 bits (672), Expect = 2e-72
Identities = 138/315 (43%), Positives = 207/315 (65%), Gaps = 4/315 (1%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGC 60
M IK+F+G ++P +A I L + LGR T +F + E +I E VRG DV+++Q C
Sbjct: 7 MREIKIFSGRANPRLAGDICKFLNIPLGRITLGEFPDGENACKIEEDVRGRDVFLIQPTC 66
Query: 61 GEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAG 120
+N+N+MEL IMI++C+ ASA R+TAV+P F Y+RQD+K++ R PITAKL++++I+ AG
Sbjct: 67 PPVNNNIMELLIMIDSCRRASAERITAVIPYFGYARQDRKDEGRVPITAKLVSDVITAAG 126
Query: 121 ADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKE-NIPEWKSSVMVSPDAGGVKRMT 179
AD V+T+DLHA+QIQGFFN+PVD+LYA P + + + NIPE V+VSPDAG +KR
Sbjct: 127 ADRVLTMDLHAAQIQGFFNVPVDHLYAAPVLNHFFQALNIPE-DELVIVSPDAGSIKRAV 185
Query: 180 GIADRLDIDFAIIHKERQRANE-GDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALRE 238
RL AI K R A++ ++ G V+ +TAI+ DD+ T +I A+ E
Sbjct: 186 SHHRRLGGRLAICDKRRHSASDTTQENIIGGPVEGRTAIIFDDMISTAGSICGAAKTTFE 245
Query: 239 AGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAE 298
AGA +IY THG+ G+AI ++ + ++ I++T+TIP + L P + + ++ +L E
Sbjct: 246 AGAKEIYIAATHGVLCGDAIARLQAAPIKEIILTDTIPHQSG-HLLPNTKILTVAPLLGE 304
Query: 299 AIRRTHYAESVSYLF 313
AI+R H ES+S +F
Sbjct: 305 AIKRIHNDESISAIF 319
>UniRef50_Q88Z84 Cluster: Ribose-phosphate pyrophosphokinase 1;
n=77; Bacteria|Rep: Ribose-phosphate pyrophosphokinase 1
- Lactobacillus plantarum
Length = 326
Score = 273 bits (669), Expect = 4e-72
Identities = 135/314 (42%), Positives = 207/314 (65%), Gaps = 2/314 (0%)
Query: 2 PNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCG 61
P +K+F +S+ +A+ I +G+ LG+ + +FS+ E + I ES+RG+ VYI+QS
Sbjct: 8 PKLKIFALNSNKPLAEKIADAVGVKLGKTSVDRFSDGEIRINIEESIRGDQVYIIQSTSA 67
Query: 62 EINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGA 121
+NDNLMEL IMI+A + ASA + V+P + Y+RQD+K +SR PITAKL+AN++ AGA
Sbjct: 68 PVNDNLMELLIMIDALRRASAKTINVVIPYYGYARQDRKARSREPITAKLVANMLETAGA 127
Query: 122 DHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGI 181
++ +DLHA+QIQGFF+IP+D+L P + + + + +++V+VSPD GGV R +
Sbjct: 128 TRILALDLHAAQIQGFFDIPLDHLMGAPLLADYFLNHHLD-ENAVVVSPDHGGVTRARKL 186
Query: 182 ADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGA 241
A+ L AII K R RAN + ++GDVK K AIM+DD+ DT TI GA+AL +AGA
Sbjct: 187 AEFLKAPIAIIDKRRPRANVAEVMNIIGDVKGKRAIMIDDMIDTAGTITLGAQALVDAGA 246
Query: 242 NKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIR 301
++YA TH + +G AIE+I S ++ +VVT++I + K K++ + + ++ +AI+
Sbjct: 247 TEVYASCTHPVLSGPAIERIEKSPIKKLVVTDSI-ELPAAKRIDKIEQVSVGQLMGQAIK 305
Query: 302 RTHYAESVSYLFTN 315
H + VS LF N
Sbjct: 306 FIHENKPVSPLFKN 319
>UniRef50_Q9U465 Cluster: Phosphoribosylpyrophosphate synthetase;
n=11; cellular organisms|Rep:
Phosphoribosylpyrophosphate synthetase - Plasmodium
falciparum
Length = 323
Score = 272 bits (667), Expect = 8e-72
Identities = 137/321 (42%), Positives = 209/321 (65%), Gaps = 10/321 (3%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGC 60
M N +F+G+S+P ++K + LG +LGR K+F++ E +++ ES+RG+DVYI+Q C
Sbjct: 1 MENAILFSGTSNPLLSKNVADHLGTSLGRVNLKRFADGEVSMQFLESIRGKDVYIIQPTC 60
Query: 61 GEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAG 120
+N+NL+EL +MI+ C+ ASA ++TAV+P + Y+RQD+K SR PI+A +A +I G
Sbjct: 61 PPVNENLIELLLMISTCRRASAKKITAVIPYYGYARQDRKLSSRVPISAADVARMIEAMG 120
Query: 121 ADHVITIDLHASQIQGFF--NIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRM 178
D V+ IDLH+ QIQGFF +PVDNL A+ + + + V+VSPDAGGV R
Sbjct: 121 VDRVVAIDLHSGQIQGFFGPRVPVDNLEAQLIGLDYFTKK--DLYKPVIVSPDAGGVYRA 178
Query: 179 TGIADRL------DIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKG 232
D L D A++ K R + NE + LVG+V + I+VDD+ DT T+ +
Sbjct: 179 RKFQDGLNHRGIGDCGIAMLIKPRTKPNEIEKMDLVGNVYDSDVIIVDDMIDTSGTLCEA 238
Query: 233 AEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDI 292
A+ L++ GA +++AF THG+F+G AI++I S LE +VVT+T+ KN+ C K+ + +
Sbjct: 239 AKQLKKHGARRVFAFATHGLFSGPAIDRIEKSPLEEVVVTDTVKSNKNIDSCKKITKLSV 298
Query: 293 SVMLAEAIRRTHYAESVSYLF 313
SV++A+AIRR H ES++ LF
Sbjct: 299 SVLVADAIRRIHQKESLNDLF 319
>UniRef50_A4T068 Cluster: Ribose-phosphate pyrophosphokinase; n=20;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 321
Score = 270 bits (662), Expect = 3e-71
Identities = 135/312 (43%), Positives = 209/312 (66%), Gaps = 3/312 (0%)
Query: 4 IKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEI 63
+ +FTG+++P +A+ + L L +G+A +FS+ E VEI E+VRG++V ++QS C
Sbjct: 9 LTLFTGNANPVLAEAVAKELKLPMGKAFVGRFSDGEIQVEIQENVRGKNVVVIQSTCAPT 68
Query: 64 NDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKS-RAPITAKLLANLI-SVAGA 121
ND+LMEL IMI+A K ASASR+TAV+P F Y+RQD++ +S R I+A+++AN++ SVAG
Sbjct: 69 NDSLMELMIMIDALKRASASRITAVIPYFGYARQDRRPRSARVAISARIVANMLQSVAGI 128
Query: 122 DHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGI 181
+ V+T+DLHA QIQGFF+IPVDN+YA P + ++ + K ++VSPD GGV R +
Sbjct: 129 ERVLTMDLHADQIQGFFDIPVDNIYASPVLLADLQAQKTQ-KDLIIVSPDIGGVVRARAM 187
Query: 182 ADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGA 241
A +L D AII K R +AN + L+G+V+ + +++DD+ DT T+ K AEAL+E GA
Sbjct: 188 AKQLGTDLAIIDKRRPKANVSEVMHLIGEVEGRHCVIMDDIIDTGGTLCKAAEALKERGA 247
Query: 242 NKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIR 301
+ A+ TH + +G A+ +I S L+ +VVT+TIP K++ + ++ +LAE +
Sbjct: 248 KGVTAYCTHAVLSGGAVARIAASELDELVVTDTIPLTPEAMKVTKIRQLTVAPLLAETLS 307
Query: 302 RTHYAESVSYLF 313
R +SV +F
Sbjct: 308 RISKGDSVMSMF 319
>UniRef50_Q5KCA3 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Filobasidiella neoformans|Rep: Ribose-phosphate
pyrophosphokinase - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 357
Score = 266 bits (651), Expect = 7e-70
Identities = 119/197 (60%), Positives = 165/197 (83%), Gaps = 1/197 (0%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCG- 61
+IK+ TG++HP +A+ + ARLG+ L KF + ET+V+I SVR EDV+I+QS
Sbjct: 7 SIKLLTGNAHPKLAEAVAARLGITLTPCHVSKFRSLETSVQIHSSVRDEDVFIIQSPSPP 66
Query: 62 EINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGA 121
++ND+LMEL IMI+ACK ASA R+TAV+PC+PY+RQDKK+KSRAPIT+KL+ANL++VAGA
Sbjct: 67 DVNDHLMELLIMISACKTASAKRITAVIPCYPYARQDKKDKSRAPITSKLVANLLAVAGA 126
Query: 122 DHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGI 181
DHVIT+DLHASQIQGFF+IPVDNL++EP + ++IK IP W+ +++VSPDAGG KR T +
Sbjct: 127 DHVITMDLHASQIQGFFDIPVDNLFSEPTMMQYIKSEIPGWRDAIIVSPDAGGAKRATAL 186
Query: 182 ADRLDIDFAIIHKERQR 198
AD+L++DFA+I+++R+R
Sbjct: 187 ADQLNLDFALINRKRRR 203
Score = 102 bits (245), Expect = 1e-20
Identities = 48/109 (44%), Positives = 76/109 (69%), Gaps = 1/109 (0%)
Query: 206 VLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSS 265
+LVGDVK K AI++DD+ DT T+ A LRE GA ++YA ++HG+ + +E +++
Sbjct: 243 LLVGDVKGKVAILIDDMIDTGHTVRLAAGVLRENGAKEVYALVSHGLLSDTTMENLSDLP 302
Query: 266 LEAIVVTNTIPQEKNMKLC-PKLQTIDISVMLAEAIRRTHYAESVSYLF 313
++ ++VTN+I Q K + C L+T+DI+ ++AE+IRRTH ES+S LF
Sbjct: 303 VKKLIVTNSIDQTKRVIACNGLLETLDIAPVIAESIRRTHNGESISALF 351
>UniRef50_Q1AXL6 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 331
Score = 263 bits (644), Expect = 5e-69
Identities = 133/311 (42%), Positives = 198/311 (63%), Gaps = 2/311 (0%)
Query: 4 IKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEI 63
+ +F+G +P++A+ I RL L LG +FSN E ESVRG DV+IVQS C +
Sbjct: 15 LMLFSGGGYPELAERIADRLDLELGSVELVQFSNGEVYARYLESVRGSDVFIVQSLCDPV 74
Query: 64 NDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADH 123
N NLMEL +M++A K ASA + AV+P + YSRQD+K K R PITA+L+A ++ VAGAD
Sbjct: 75 NKNLMELLVMVDAAKRASAESIVAVIPWYAYSRQDRKTKPREPITARLVAEMLKVAGADR 134
Query: 124 VITIDLHASQIQGFFNIPVDNLYA-EPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIA 182
++T+DLH QI+GFF+ PVD+L A + ++ E +V+V+PD G VK +A
Sbjct: 135 IMTMDLHVGQIEGFFSFPVDHLTAMHTFVDHFVDEGFQNAPDTVVVAPDTGEVKMAKRLA 194
Query: 183 DRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGAN 242
D L + +AI++K R+ E + T ++G+V + AI++DD+ D T++ AEAL GA
Sbjct: 195 DHLGLPWAIVNKIRRGPGESEVTHVIGEVSGRRAILIDDIIDGGGTMVGAAEALLSEGAT 254
Query: 243 KIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRR 302
++YA TH +F+G A E+I S + +VVT+T+P K K K++T+ I+ +LA IR
Sbjct: 255 EVYAAATHAVFSGRAYERIEESPIREVVVTDTLPL-KPGKPRSKIRTLTIAPILASTIRN 313
Query: 303 THYAESVSYLF 313
+SVS +F
Sbjct: 314 VFTDDSVSAVF 324
>UniRef50_P65239 Cluster: Ribose-phosphate pyrophosphokinase 1;
n=143; Bacteria|Rep: Ribose-phosphate pyrophosphokinase
1 - Streptococcus pneumoniae
Length = 322
Score = 260 bits (636), Expect = 4e-68
Identities = 133/315 (42%), Positives = 205/315 (65%), Gaps = 7/315 (2%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGE 62
++K+F SS+ ++A+ + +G+ LG+++ ++FS+ E V I ES+RG+ V+I+QS
Sbjct: 5 DLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQVNIEESIRGKHVFILQSTSSP 64
Query: 63 INDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGAD 122
+NDNL+E+ IM++A K ASA V V+P + Y+RQD+K ++R PIT+KL+AN++ VAG D
Sbjct: 65 VNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRKARAREPITSKLVANMLEVAGVD 124
Query: 123 HVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIA 182
++TIDLHA+QIQGFF+IPVD+L P I + + V+VSPD GGV R +A
Sbjct: 125 RLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERRGMVGSDYVVVSPDHGGVTRARKLA 184
Query: 183 DRLDIDFAIIHKER--QRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAG 240
+ L AII K R + N + ++G V+ KT I++DD+ DT TI A+AL EAG
Sbjct: 185 EFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGKTCILIDDMIDTAGTICHAADALAEAG 244
Query: 241 ANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTI--PQEKNMKLCPKLQTIDISVMLAE 298
A ++YA TH + +G A + I S+++ +VV +TI P+E +L K++ I I+ +L +
Sbjct: 245 AVEVYASCTHPVLSGPATDNIQKSAIKKLVVLDTIYLPEE---RLIDKIEQISIAHLLGD 301
Query: 299 AIRRTHYAESVSYLF 313
AI R H +S LF
Sbjct: 302 AIVRIHEKRPLSPLF 316
>UniRef50_Q1GEV9 Cluster: Ribose-phosphate pyrophosphokinase; n=11;
Alphaproteobacteria|Rep: Ribose-phosphate
pyrophosphokinase - Silicibacter sp. (strain TM1040)
Length = 340
Score = 259 bits (635), Expect = 6e-68
Identities = 124/316 (39%), Positives = 210/316 (66%), Gaps = 7/316 (2%)
Query: 5 KVFTGSSHPDIAKTIVARLGLNLG------RATTKKFSNKETNVEIGESVRGEDVYIVQS 58
K+ +G+++ +AK+I R+ ++ G A ++F++ E VE+ E+VRGED++I+Q
Sbjct: 8 KLISGNANLPLAKSISRRMSMHRGVDQDLVNARVERFNDGEIFVEVYENVRGEDMFIIQP 67
Query: 59 GCGEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISV 118
NDNLMEL I+ +A + +SA R+TAV+P F Y+RQD++ K+R PI+AK++AN+++
Sbjct: 68 TSNPANDNLMELLIIADALRRSSAQRITAVIPYFGYARQDRRTKARTPISAKMVANMLTG 127
Query: 119 AGADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVM-VSPDAGGVKR 177
AG + V+T+DLHA+QIQGFF+IPVDNLYA P +K + +M VSPD GGV R
Sbjct: 128 AGIERVLTMDLHAAQIQGFFDIPVDNLYASPIFALDVKAQFKDQMDDLMVVSPDVGGVAR 187
Query: 178 MTGIADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALR 237
+A R++ +I+ K R++A E ++GDVK+K ++VDD+ DT T+ K A+ L
Sbjct: 188 ARELAKRINAPLSIVDKRREKAGEIAEMTVIGDVKDKICLIVDDICDTAGTLCKAAQILL 247
Query: 238 EAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLA 297
+ GA +++A+++HG+ +G A+E++ NS ++++V+T++I + + P ++ + + +
Sbjct: 248 DNGAKEVHAYISHGVMSGPAVERVTNSVMKSLVLTDSIQPTQPILDAPNIRIVPTAPLFT 307
Query: 298 EAIRRTHYAESVSYLF 313
+AI + SVS LF
Sbjct: 308 QAILNIWHGTSVSSLF 323
>UniRef50_A0VM43 Cluster: Ribose-phosphate pyrophosphokinase; n=20;
Proteobacteria|Rep: Ribose-phosphate pyrophosphokinase -
Dinoroseobacter shibae DFL 12
Length = 340
Score = 258 bits (631), Expect = 2e-67
Identities = 127/316 (40%), Positives = 208/316 (65%), Gaps = 7/316 (2%)
Query: 5 KVFTGSSHPDIAKTIVARL----GLNLGR--ATTKKFSNKETNVEIGESVRGEDVYIVQS 58
K+ +G+++ ++A I R+ G+ +G A ++F++ E VE+ E+VRGED++I+QS
Sbjct: 8 KIISGNANQELAHAISRRMSAYRGMTVGLVDARVERFNDGEIFVEVFENVRGEDMFIIQS 67
Query: 59 GCGEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISV 118
NDNLMEL IM +A + +SA+R+TA++P F Y+RQD++ K+R PITAKL+AN++
Sbjct: 68 TSNPANDNLMELLIMCDALRRSSAARITAIIPYFGYARQDRRTKARTPITAKLVANMMVE 127
Query: 119 AGADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSV-MVSPDAGGVKR 177
AG + V+T+DLHA+QIQGFF+IPVDNLYA P + N +V +VSPD GGV R
Sbjct: 128 AGIERVLTMDLHAAQIQGFFDIPVDNLYAAPIFALDVMHNFAGRLDNVTVVSPDVGGVAR 187
Query: 178 MTGIADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALR 237
+A R+ AI+ K R + + ++G+V+ +T I+VDD+ DT T+ K A+ L
Sbjct: 188 ARELAQRIGCGLAIVDKRRSQPGVVEEMTVIGEVEGQTCIIVDDICDTAGTLCKAADLLI 247
Query: 238 EAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLA 297
GA+++++++THG+ +G A+E+I S+++++V+T++I +K P ++ + + + A
Sbjct: 248 SEGASEVHSYITHGVLSGPAVERITKSNMKSLVITDSIGATDAVKAAPNIRIVPTAPVFA 307
Query: 298 EAIRRTHYAESVSYLF 313
+AI SVS LF
Sbjct: 308 QAILNIWNGTSVSSLF 323
>UniRef50_Q4P9A7 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Ustilago maydis|Rep: Ribose-phosphate pyrophosphokinase
- Ustilago maydis (Smut fungus)
Length = 458
Score = 258 bits (631), Expect = 2e-67
Identities = 115/199 (57%), Positives = 160/199 (80%), Gaps = 3/199 (1%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCG- 61
+IK+ TG+SHP++A+ + RLG+ L KKF+++ +V IG SVR EDVY++Q+G
Sbjct: 6 SIKLLTGNSHPELAQQVADRLGIPLTPCVCKKFADQSIDVRIGSSVRDEDVYVLQTGNSP 65
Query: 62 --EINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVA 119
+ ND+LMEL I+++ACK ASA R+TAV+P FPYSR DKK+KSRAPITAKL+AN+++VA
Sbjct: 66 YTDPNDSLMELLILLSACKTASARRITAVIPSFPYSRHDKKDKSRAPITAKLVANMLTVA 125
Query: 120 GADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMT 179
GADHVIT+DLHASQIQGFF+IPVDNL +EP++ +WI+ + W+ +++VSPDAGG KR T
Sbjct: 126 GADHVITMDLHASQIQGFFDIPVDNLTSEPSVARWIRSKVENWREAIIVSPDAGGAKRAT 185
Query: 180 GIADRLDIDFAIIHKERQR 198
+AD L +DFA+I++ R+R
Sbjct: 186 ALADSLGVDFALINRNRRR 204
Score = 110 bits (264), Expect = 5e-23
Identities = 53/115 (46%), Positives = 75/115 (65%), Gaps = 1/115 (0%)
Query: 200 NEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIE 259
N +LVGDVK K AI+VDD+ DT T+ A+ L AGA K+YA +THG+ +G +I+
Sbjct: 336 NSSRMEILVGDVKGKVAILVDDMVDTGRTLALAAKTLEAAGAAKVYAIITHGLLSGQSID 395
Query: 260 KINNSSLEAIVVTNTIPQEKNMKLCP-KLQTIDISVMLAEAIRRTHYAESVSYLF 313
+ SLE +VVTNTI + K KL+ +D+S ++ E IRR+H+ ES+S LF
Sbjct: 396 LLRKLSLERLVVTNTIANTEKAKASEGKLEIMDVSAVIGETIRRSHHGESISQLF 450
>UniRef50_Q83GR1 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Actinomycetales|Rep: Ribose-phosphate pyrophosphokinase
- Tropheryma whipplei (strain Twist) (Whipple's
bacillus)
Length = 348
Score = 255 bits (625), Expect = 1e-66
Identities = 131/302 (43%), Positives = 198/302 (65%), Gaps = 8/302 (2%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGC 60
M N+ + G SHPD+A+ LG+ L + + F+N E SVRG+DV+++Q+GC
Sbjct: 31 MRNLVLIAGRSHPDLARATAESLGVGLLQTDIRTFANGEIYTRFNSSVRGKDVFVLQTGC 90
Query: 61 GEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAG 120
+ND L+EL ++I++CK ASA ++AV PC+PYSRQD+K R PI+A+L+A+LI+ AG
Sbjct: 91 DPVNDGLVELLLLIDSCKRASAKHISAVTPCYPYSRQDRKGYGREPISARLVADLIACAG 150
Query: 121 ADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTG 180
AD +IT+DLHASQIQGFFN PVD+L PA+ K +K + +VSPD G VK
Sbjct: 151 ADRIITVDLHASQIQGFFNGPVDHLTGVPALIKHVKS--LRIDNLTIVSPDIGRVKVADV 208
Query: 181 IADRLDIDFAIIHKERQRANEGDSTV--LVGDVKNKTAIMVDDLADTCDTILKGAEALRE 238
+D+L+ AIIHK R + T+ +VGDV+++ ++VDDL DT DT+ K A AL++
Sbjct: 209 WSDKLNAPLAIIHKRRDPRVHNNVTMHEIVGDVRSRVCLVVDDLIDTGDTLAKAAIALKK 268
Query: 239 AGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAE 298
AGA K+ A THGIF+ ++ ++ ++VT+++P K+ +++T+ I+ +LA
Sbjct: 269 AGAVKVIAAATHGIFS-TPERLVSCGEIDHVIVTDSVPAS---KVFDRVKTVSIAPLLAC 324
Query: 299 AI 300
AI
Sbjct: 325 AI 326
>UniRef50_A5V1W5 Cluster: Ribose-phosphate pyrophosphokinase; n=5;
Chloroflexi (class)|Rep: Ribose-phosphate
pyrophosphokinase - Roseiflexus sp. RS-1
Length = 327
Score = 250 bits (613), Expect = 3e-65
Identities = 127/316 (40%), Positives = 197/316 (62%), Gaps = 9/316 (2%)
Query: 4 IKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEI 63
+++ +G+ +P +A+ I RLG+ LG T +F+N+ V + ESVR +DV+++QS +
Sbjct: 8 LRILSGNGNPALAQAICNRLGVRLGDVTITRFANENIFVRLNESVREKDVFVIQSLASPL 67
Query: 64 NDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADH 123
+D ++EL IM++AC+ ASA RVTAVVP + Y R DK+++ R PITA+LLA++I VAGA
Sbjct: 68 SDRILELLIMLDACRRASAGRVTAVVPFYAYGRTDKRDQPRVPITARLLADMIQVAGAQQ 127
Query: 124 VITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIAD 183
++TIDLHA QIQGFF+IPVD L + ++ ++ W V+VS D G KR A+
Sbjct: 128 LVTIDLHAGQIQGFFSIPVDELSCMGLLVRYFRDR--GWDDVVVVSSDIGFAKRARNFAE 185
Query: 184 RLDIDFAIIHKER-QRANE-----GDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALR 237
+L AI+ K RA+ GD+ L+GDV K I+VDD +T +++ AE L
Sbjct: 186 QLGAPLAIVEKRHTARADTDGEEGGDAVSLIGDVAGKRCILVDDEVNTGRSLINAAELLE 245
Query: 238 EAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLA 297
GA ++YA + H + G+ E++ NS++ +V T+T+P K P L+ + ++ +LA
Sbjct: 246 RRGAREVYAAIVHPVLGGDGAERLRNSAIRELVTTDTLPVPAE-KSWPGLRILTVAPLLA 304
Query: 298 EAIRRTHYAESVSYLF 313
E I+R H SV +F
Sbjct: 305 EVIQRIHSGVSVHTIF 320
>UniRef50_Q9RUD2 Cluster: Probable ribose-phosphate
pyrophosphokinase; n=7; Bacteria|Rep: Probable
ribose-phosphate pyrophosphokinase - Deinococcus
radiodurans
Length = 320
Score = 250 bits (611), Expect = 5e-65
Identities = 128/311 (41%), Positives = 193/311 (62%), Gaps = 2/311 (0%)
Query: 6 VFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEIND 65
VF+G S+ +A+ I LG+ LGR+ T+KF+N V ES+R DV+IVQ+ ++D
Sbjct: 10 VFSGQSNRPLAQAICDNLGVPLGRSRTEKFTNDNLIVHYEESLREGDVFIVQTFSTPVSD 69
Query: 66 NLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVI 125
+MEL +MI+A K ASA RVTAV+P + Y+R DKK+ R I +L+A+L+ AGAD V+
Sbjct: 70 AIMELMLMIDAAKSASAGRVTAVIPYYSYARSDKKDSPRISIAGRLVADLLQEAGADRVL 129
Query: 126 TIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRL 185
T+ LH+ Q+ GFF +PVD+L A+ +++ K+ +P+ + V+++PDAG +KR + IA RL
Sbjct: 130 TMTLHSPQVHGFFKVPVDHLSADVVLSQHFKKCVPDAHNGVVLAPDAGSIKRASQIARRL 189
Query: 186 DIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIY 245
D A+I KER E L+GDV KT +VDD T ++++ R GA +Y
Sbjct: 190 DSGLAMIDKERLSDTEVRPRALIGDVDGKTVFIVDDEISTAGSLVETVSIARSMGAKDVY 249
Query: 246 AFLTHGIFAGNAIEKINNSSLEAIVVTNT--IPQEKNMKLCPKLQTIDISVMLAEAIRRT 303
+THG+++G AIE+I + + NT +PQ+K + KL +D++ + A AI
Sbjct: 250 VAVTHGVYSGPAIERIAALDVTQVASCNTVLVPQDKLDRAGGKLAVLDVAPLFASAIANI 309
Query: 304 HYAESVSYLFT 314
H SVS LFT
Sbjct: 310 HTGASVSTLFT 320
>UniRef50_A4VV92 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Streptococcus suis|Rep: Ribose-phosphate
pyrophosphokinase - Streptococcus suis (strain 05ZYH33)
Length = 333
Score = 249 bits (610), Expect = 6e-65
Identities = 134/312 (42%), Positives = 202/312 (64%), Gaps = 5/312 (1%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGE 62
NIK+F+ +S+ DIA+ I G+ LG+ ++++FS+ E + I ESVRG DVYI+QS
Sbjct: 17 NIKLFSLNSNRDIAEKIADSAGIPLGKLSSRQFSDGEIQINIEESVRGVDVYIIQSTSYP 76
Query: 63 INDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGAD 122
+N++L EL IMI+ACK ASA+ +TAV+P F Y+RQD+ R PITAKL+AN++ AG D
Sbjct: 77 VNNHLWELLIMIDACKRASANTITAVIPYFGYARQDRTASPREPITAKLVANMLVKAGVD 136
Query: 123 HVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIA 182
V+T+DLHASQIQGFF+IPVDNL EP + E + V+VSP G+KR IA
Sbjct: 137 RVLTLDLHASQIQGFFDIPVDNLLTEPLFAAYYMEKGLCGEDVVIVSPKNSGIKRARNIA 196
Query: 183 DRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGAN 242
+ L+ AII Q +E ++GDV K AI+VDD+ +T T + ++ ++E GA
Sbjct: 197 EFLNAPIAII-DYAQDDSERSEGYIIGDVAGKKAILVDDILNTGRTFSQASKIVQEGGAT 255
Query: 243 KIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPK-LQTIDISVMLAEAIR 301
+IYA +HG+FAG A + ++ + ++ I+VT+++ ++ PK + + S ++A+AI
Sbjct: 256 EIYAVASHGLFAGTAAQLLDEAPIKEILVTDSVASKEQH---PKNIAFLTASDLIADAIH 312
Query: 302 RTHYAESVSYLF 313
R + +S LF
Sbjct: 313 RIQEHQPLSPLF 324
>UniRef50_Q6MAT0 Cluster: Probable phosphoribosyl pyrophosphate
synthetase; n=1; Candidatus Protochlamydia amoebophila
UWE25|Rep: Probable phosphoribosyl pyrophosphate
synthetase - Protochlamydia amoebophila (strain UWE25)
Length = 313
Score = 248 bits (607), Expect = 1e-64
Identities = 127/307 (41%), Positives = 195/307 (63%), Gaps = 2/307 (0%)
Query: 6 VFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEIND 65
+F GSSHP +A I +L ++LG+ KF + E V++ ESVRG+D +++QS + N
Sbjct: 9 LFAGSSHPILATEIAQQLKISLGQMQLSKFPDGEIGVQLLESVRGKDTFVLQSIALDPNF 68
Query: 66 NLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVI 125
LMEL I+++A K ASA + AV+P + Y RQD+K+K ITAKL+ANL+ AG ++
Sbjct: 69 YLMELLIIVDALKRASARNIVAVIPYYGYCRQDRKDKFDVSITAKLVANLLVEAGITRIL 128
Query: 126 TIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRL 185
T+DLH Q+QGFF+IPVD+L + +++ + +S++V+PD G VK A +L
Sbjct: 129 TMDLHVDQLQGFFDIPVDHLSGRQLLIDELQK--LDLTNSIVVAPDIGSVKTARTFASQL 186
Query: 186 DIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIY 245
+DFAI+ K R+ A E L+GDV K ++ DD+ T T++ A+A +E GAN+I+
Sbjct: 187 SVDFAIVDKHRKSAIEVVDYHLIGDVNGKDVLLADDICSTGATLMSAAKACQEKGANRIF 246
Query: 246 AFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRRTHY 305
A THG+ +++++I NS LE + +TNTIP K +K KL+T+ I+ +L AI+
Sbjct: 247 AAFTHGLLVDDSVKQIENSLLEIVWMTNTIPHTKRLKEASKLKTVSIASLLTHAIQCIVS 306
Query: 306 AESVSYL 312
ES+S L
Sbjct: 307 DESISSL 313
>UniRef50_Q7MT83 Cluster: Ribose-phosphate pyrophosphokinase; n=25;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Porphyromonas gingivalis (Bacteroides gingivalis)
Length = 313
Score = 248 bits (607), Expect = 1e-64
Identities = 126/311 (40%), Positives = 198/311 (63%), Gaps = 5/311 (1%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGE 62
N VF+G++ +A+ I LG LGR + F++ E V ES+RG DV++VQS
Sbjct: 6 NFSVFSGTNSRYLAEKICNSLGCPLGRMNIEHFADGEFAVSYEESIRGRDVFLVQSTFPS 65
Query: 63 INDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGAD 122
+DNLMEL +MI+A K ASA +TAV+P F ++RQD+K+K R I AKL+A+L+S AG
Sbjct: 66 -SDNLMELLLMIDAAKRASAHYITAVIPYFGWARQDRKDKPRVSIGAKLIADLLSKAGIT 124
Query: 123 HVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIA 182
+IT+DLHA QIQGFF++PVD+LY ++I++N+P ++ V+ +PD GG KR A
Sbjct: 125 RLITMDLHADQIQGFFDVPVDHLYGSTVFMEYIRKNMP-LENLVVATPDVGGTKRANSYA 183
Query: 183 DRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGAN 242
L + I HK R +ANE ++GDV++K ++VDD+ DT TI K A+ ++E GA
Sbjct: 184 KHLGVPMVICHKSRLKANEIAEMRIIGDVQDKDVLLVDDIVDTAGTITKAADLMKENGAR 243
Query: 243 KIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRR 302
+ A +H + + A +++ S+L+ ++ T++IP C K++ + ++ + AEAI+R
Sbjct: 244 SVCAIASHAVMSDPASMRVDQSTLKEMIFTDSIPYPHK---CEKVKILSVADLFAEAIKR 300
Query: 303 THYAESVSYLF 313
ES++ L+
Sbjct: 301 VCSHESITTLY 311
>UniRef50_A4EBQ1 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 328
Score = 248 bits (606), Expect = 2e-64
Identities = 131/311 (42%), Positives = 193/311 (62%), Gaps = 5/311 (1%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCG- 61
+I+V++GSS+ +A+ I LG+ L T K+F+N E E+VRG DV+++QS G
Sbjct: 15 SIRVYSGSSNRPLAQKIAEYLGVELSGLTLKQFANGEIYARYDETVRGADVFLIQSVAGG 74
Query: 62 EINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGA 121
+ND LMEL I +A K ASA +TAV+ + Y+RQD+K R PITA+L+ANL+ AG
Sbjct: 75 NVNDMLMELLIATDAAKRASARSITAVITHYGYARQDRKAGPREPITARLVANLLERAGV 134
Query: 122 DHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGI 181
D +IT+DLH QIQGFF+IPV++L A P ++ + + + V+VSPD G K +
Sbjct: 135 DRIITLDLHQGQIQGFFDIPVNHLSALPLFGQYYNDMHFDTDNLVVVSPDVGRAKAAKKL 194
Query: 182 ADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGA 241
+D L D AI HK R R N + ++GD+K KT ++ DD+ DT T+ + L+ GA
Sbjct: 195 SDMLGCDLAIAHKGRPRHNAAEVMGIIGDIKGKTCVINDDMIDTAGTLCANVKELKAMGA 254
Query: 242 NKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIR 301
IY THGIF+G AIE++N++ + VVT+ IP E + K++TI ++ A+AI
Sbjct: 255 GDIYVCATHGIFSGPAIERLNDAPIVECVVTDAIPVE----VGGKIKTISVAEEFAQAIS 310
Query: 302 RTHYAESVSYL 312
++ E VS L
Sbjct: 311 AVYHEEPVSTL 321
>UniRef50_Q5A4X7 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Candida albicans|Rep: Ribose-phosphate pyrophosphokinase
- Candida albicans (Yeast)
Length = 404
Score = 248 bits (606), Expect = 2e-64
Identities = 109/201 (54%), Positives = 156/201 (77%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGC 60
M K+F GSSHP++ + + RLG+ T KKFSN ET+V+IG SVR EDVYI+QSG
Sbjct: 1 MRKCKIFVGSSHPELGQLVCDRLGVEPAPCTLKKFSNGETSVQIGVSVRDEDVYIIQSGS 60
Query: 61 GEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAG 120
IND++MEL I+I+AC+ SA+++TAV+P FPYS+Q K +K R ITA++LANL+ +AG
Sbjct: 61 PHINDHIMELLILISACRGGSANKITAVIPQFPYSKQSKMKKHRGAITARMLANLLVMAG 120
Query: 121 ADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTG 180
ADHV+++DLHASQ+QGFF+ PVDNL+ P + +WI+ +IP+W+++V+VS + GG KR+T
Sbjct: 121 ADHVVSMDLHASQMQGFFSKPVDNLFGAPTLARWIRHHIPDWENAVVVSKNPGGTKRVTA 180
Query: 181 IADRLDIDFAIIHKERQRANE 201
+AD L I+FA+IH +R+R +
Sbjct: 181 LADSLKINFAMIHTDRRRTQD 201
Score = 90.2 bits (214), Expect = 6e-17
Identities = 51/126 (40%), Positives = 74/126 (58%), Gaps = 4/126 (3%)
Query: 195 ERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALR-EAGANKIYAFLTHGIF 253
E ++E LVGDVK+K AI++DD+ D ++ + AE LR GA +Y THG+F
Sbjct: 275 ETTTSSEEKLITLVGDVKDKVAIILDDMIDKPNSFIAAAEHLRLNCGAKAVYVVGTHGVF 334
Query: 254 AGNAIEKINNSS-LEAIVVTNTIPQEKNM--KLCPKLQTIDISVMLAEAIRRTHYAESVS 310
++ + +S ++ IVVTNT P K K KL ID+S + AE IRR H+ ES+S
Sbjct: 335 NDKCLKDLTDSKCIDKIVVTNTYPISKEQIEKHKDKLVVIDVSPIFAECIRRDHFGESIS 394
Query: 311 YLFTNV 316
LF ++
Sbjct: 395 VLFDSL 400
>UniRef50_A6R925 Cluster: Ribose-phosphate pyrophosphokinase I;
n=20; Pezizomycotina|Rep: Ribose-phosphate
pyrophosphokinase I - Ajellomyces capsulatus NAm1
Length = 456
Score = 247 bits (605), Expect = 3e-64
Identities = 113/207 (54%), Positives = 160/207 (77%), Gaps = 4/207 (1%)
Query: 111 LLANLISVAGADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSP 170
L+A+L++ AGADH+IT+DLH Q QGFF+IPVDNLY P + K+I ENIP +K+S++VSP
Sbjct: 247 LVADLLTCAGADHIITMDLHDPQYQGFFDIPVDNLYGRPLLKKYITENIPNYKASIIVSP 306
Query: 171 DAGGVKRMTGIADRLDIDFAIIHKERQRANEGD----STVLVGDVKNKTAIMVDDLADTC 226
DAGG KR T IAD L +DFA+IHKER+ D + +LVGDV +TAI++DDLADT
Sbjct: 307 DAGGAKRATAIADSLGMDFALIHKERRPTKITDRQNATMMLVGDVNGRTAILIDDLADTS 366
Query: 227 DTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPK 286
+TI + A+ L++ GA+++YA +THGI +G+AIE+IN S+L+ +VVTNT+ Q+++ CPK
Sbjct: 367 NTITRAAKLLKKEGASRVYALVTHGILSGDAIERINASALDKVVVTNTVAQDEHRTRCPK 426
Query: 287 LQTIDISVMLAEAIRRTHYAESVSYLF 313
L+ +++ + AEAIRR H+ ES+S LF
Sbjct: 427 LEVLEVGHVFAEAIRRVHHGESISVLF 453
Score = 121 bits (292), Expect = 2e-26
Identities = 59/95 (62%), Positives = 70/95 (73%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGE 62
NI V GSSHP + K I LG+ L KFS ET VEI ESVRG+DVYI+QSG G+
Sbjct: 4 NIIVLGGSSHPHLNKAICEHLGIPLANVLLSKFSVGETRVEINESVRGKDVYIIQSGGGK 63
Query: 63 INDNLMELFIMINACKIASASRVTAVVPCFPYSRQ 97
+ND+LMEL ++I+ACK ASA RVTAV+P FPYSRQ
Sbjct: 64 VNDHLMELLVIISACKTASAKRVTAVLPLFPYSRQ 98
>UniRef50_A5URX1 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Roseiflexus sp. RS-1
Length = 315
Score = 244 bits (598), Expect = 2e-63
Identities = 127/309 (41%), Positives = 194/309 (62%), Gaps = 4/309 (1%)
Query: 6 VFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEIND 65
+F GS P + K I A LG+ G+ +FS V I E+VRG VYIVQS ND
Sbjct: 8 IFPGSGSPKLTKNICAYLGVTPGQCEVLRFSEGNLFVRILENVRGRHVYIVQSTAYPAND 67
Query: 66 NLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVI 125
N MEL I+A K ASA+ VTAVVP F Y++ DKK++ R I A++ A+ I AGAD ++
Sbjct: 68 NFMELLFWIDAFKRASAASVTAVVPFFSYAKGDKKDEPRVSIRARVCADAIEAAGADRIV 127
Query: 126 TIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRL 185
+DLHA QIQGFF IPVD+LYA P + +++ ++ ++V+PD+G K+ A L
Sbjct: 128 VMDLHAPQIQGFFKIPVDDLYALPVLCDRVRQ--MNLENLIVVAPDSGFAKKARKYARYL 185
Query: 186 DIDFAIIHKERQRANEGDSTV-LVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKI 244
+ A+ KER +E V ++GDV+ KTA++VDD + T+++ AE L GA ++
Sbjct: 186 GVSMAVGDKERVAHDEHAHIVEIIGDVQGKTALIVDDFTISAGTLVEVAEQLLVRGAKEV 245
Query: 245 YAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRRTH 304
YA +THG+FA ++E++ +S + + +T+T+ + + + L P+++ + ++ + EAIRR H
Sbjct: 246 YAAVTHGVFARGSMERLADSPIRRLFITDTV-ETQPITLTPQIEVVSVAPLFGEAIRRIH 304
Query: 305 YAESVSYLF 313
Y ES+S LF
Sbjct: 305 YRESISVLF 313
>UniRef50_Q8Y9L8 Cluster: Ribose-phosphate pyrophosphokinase 2;
n=15; Bacilli|Rep: Ribose-phosphate pyrophosphokinase 2
- Listeria monocytogenes
Length = 311
Score = 243 bits (594), Expect = 5e-63
Identities = 132/310 (42%), Positives = 195/310 (62%), Gaps = 3/310 (0%)
Query: 4 IKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEI 63
+K+F+ +S +A I L + L +KFS+ E + I ES+RG + Y+VQS +
Sbjct: 5 MKLFSVTSERPLATKIADYLDIPLCEVELQKFSDGEVKINIEESIRGTNAYVVQSMNSNV 64
Query: 64 NDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADH 123
N+ LMEL IM++A K AS + ++P + Y+RQD+K +SR PITAKL+ANLI AGA+
Sbjct: 65 NERLMELLIMVDALKRASVHSINIIMPYYGYARQDRKARSREPITAKLMANLIQRAGANR 124
Query: 124 VITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIAD 183
+IT+DLHA+QIQGFFNIP+D+L A P I ++ EN E K V+V+PD GV R IAD
Sbjct: 125 LITVDLHAAQIQGFFNIPIDHLSAIPLIGDYLIENYGE-KDVVVVAPDHSGVVRARRIAD 183
Query: 184 RLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANK 243
RL+ AI+++ + R +E + ++GDVK K AI+VDD+ DT A+ L E GA +
Sbjct: 184 RLNAPIAILNR-KPRPHEDEIMSVIGDVKGKVAIVVDDIIDTGVRATTSADILLEKGAVE 242
Query: 244 IYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRRT 303
+ A TH + AGNA E++ NS+++ ++ +++I ++ K KL TI I +L AI
Sbjct: 243 VIACATHSVMAGNATERLQNSNIKEVITSDSIDLPED-KQFDKLTTISIGRILGRAIEGV 301
Query: 304 HYAESVSYLF 313
S+ LF
Sbjct: 302 QENRSLHPLF 311
>UniRef50_P32895 Cluster: Ribose-phosphate pyrophosphokinase 1;
n=11; Ascomycota|Rep: Ribose-phosphate pyrophosphokinase
1 - Saccharomyces cerevisiae (Baker's yeast)
Length = 427
Score = 241 bits (589), Expect = 2e-62
Identities = 105/201 (52%), Positives = 154/201 (76%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGC 60
M K+F G+SHP++ + RLG+ T KKF+N ET+V+IG SVR EDVY++QSG
Sbjct: 1 MRKCKIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGS 60
Query: 61 GEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAG 120
IND++MEL I+++AC+ SA ++TAV+P FPYS+Q K ++ R ITA++LANL+ +AG
Sbjct: 61 PSINDDIMELLILVSACRGGSARKITAVIPQFPYSKQCKMKRHRGAITARMLANLLVMAG 120
Query: 121 ADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTG 180
ADHV+++DLHASQ+QGFF PVDNLY P++ KWI+EN+ +++ +V+VS + GG KR+T
Sbjct: 121 ADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENVEDYEDAVVVSKNPGGTKRVTA 180
Query: 181 IADRLDIDFAIIHKERQRANE 201
+AD L I+FA+IH +R+R+ +
Sbjct: 181 LADSLKINFAMIHTDRRRSKD 201
Score = 95.1 bits (226), Expect = 2e-18
Identities = 49/113 (43%), Positives = 74/113 (65%), Gaps = 3/113 (2%)
Query: 207 LVGDVKNKTAIMVDDLADTCDTILKGAEAL-REAGANKIYAFLTHGIFAGNAIEKINNS- 264
LVG+V+ ++AI++DD+ D + + AE L + GA K+Y THGIF G+ +E++ S
Sbjct: 312 LVGNVRGRSAIILDDMIDRPGSFISAAEHLVQNCGAKKVYVVATHGIFTGDCLEELEKSD 371
Query: 265 SLEAIVVTNTIP-QEKNMKLCPKLQTIDISVMLAEAIRRTHYAESVSYLFTNV 316
+++ IVVTNT P + + KL TID+S + AE IRR HY ES+S LF ++
Sbjct: 372 AIDTIVVTNTYPISGERIAGSKKLVTIDVSPIFAECIRRDHYGESISVLFDSL 424
>UniRef50_A1CDQ3 Cluster: Ribose-phosphate pyrophosphokinase; n=5;
Pezizomycotina|Rep: Ribose-phosphate pyrophosphokinase -
Aspergillus clavatus
Length = 489
Score = 239 bits (585), Expect = 7e-62
Identities = 118/220 (53%), Positives = 156/220 (70%), Gaps = 5/220 (2%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGC 60
M +++F+G+SHP +A+TI RLG RA KF+N ET V+IG SVR +DVYI+QSG
Sbjct: 1 MRGVQIFSGTSHPVLAETICERLGTLPARALLGKFANGETRVDIGVSVRNQDVYILQSGS 60
Query: 61 GEINDNLMELFIMINACKIASASRVTAV-VPCFPYSRQDKKEKSRAPITAKLLANLISVA 119
+IND++MEL IMI+ACK SA +T FPYSRQ KK+ R ITA++LANL+SVA
Sbjct: 61 QKINDSVMELLIMISACKGGSAKSITGQWTRYFPYSRQSKKKSHRGAITARMLANLLSVA 120
Query: 120 GADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMT 179
G DHVIT+DLHASQ+QGFF PVDNL+AEP I +WI+ N+P WK +V+VS +AGG KR+T
Sbjct: 121 GVDHVITLDLHASQMQGFFGKPVDNLFAEPFIARWIRMNVPGWKEAVVVSKNAGGTKRVT 180
Query: 180 GIADRLDIDFAIIHKERQRANEG----DSTVLVGDVKNKT 215
+AD L ++F I+ +R+R DSTV + + T
Sbjct: 181 SLADTLKLNFGIVTTDRRRPKTAMAMTDSTVFFDSIDDDT 220
Score = 101 bits (243), Expect = 2e-20
Identities = 54/119 (45%), Positives = 77/119 (64%), Gaps = 3/119 (2%)
Query: 198 RANEGDSTV-LVGDVKNKTAIMVDDLADTCDTILKGAEAL-REAGANKIYAFLTHGIFAG 255
R+ E + T+ LVGDV+ +T +VDD+ D + + AE + + GA K+Y THG+F G
Sbjct: 367 RSAEQEKTITLVGDVRGRTVFLVDDMIDKSGSWVAAAETVVKRGGAKKVYCIATHGLFGG 426
Query: 256 NAIEKINN-SSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRRTHYAESVSYLF 313
+E++ ++++ IVVTNT P +M KL TIDIS +LAE+IRR HY ESVS LF
Sbjct: 427 ECLEQMEACAAIDYIVVTNTFPITPHMMKSKKLITIDISSLLAESIRRHHYGESVSALF 485
>UniRef50_Q4Q3Z4 Cluster: Phosphoribosylpyrophosphate synthetase,
putative; n=6; Trypanosomatidae|Rep:
Phosphoribosylpyrophosphate synthetase, putative -
Leishmania major
Length = 356
Score = 239 bits (584), Expect = 9e-62
Identities = 121/321 (37%), Positives = 198/321 (61%), Gaps = 8/321 (2%)
Query: 4 IKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCG-- 61
I++ +G+++PD+ + L ++ R K+F+N E N+++ ++VRG+D +I+Q G
Sbjct: 36 IRLISGTANPDLTDNVAKCLNVDKCRTEIKRFANGELNIKVVDNVRGDDCFIIQPTAGGF 95
Query: 62 --EINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVA 119
++N +MEL ++++ K++SA R+TA+VP + YSRQD+K + R PI+A +A L+
Sbjct: 96 DTDVNTAMMELLLLVHTLKLSSAKRITAIVPYYAYSRQDRKSEPRVPISASAVAQLLQCM 155
Query: 120 GADHVITIDLHASQIQGFF-NIPVDNLYAEPAITKWI-KENIPEWKSSVMVSPDAGGVKR 177
G D V+T+DLH QIQGFF NIPVDNL P ++ ++ + +V+VSPDAGGV+R
Sbjct: 156 GVDRVVTMDLHCGQIQGFFRNIPVDNLLMFPEFATYLTRQPWFDKNQTVVVSPDAGGVER 215
Query: 178 MTGIADRLDIDFAI-IHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEAL 236
+ADR+ + I K R+ A + DS VG+V+ T ++VDD+ DT T+ K + L
Sbjct: 216 ANVLADRIGASHIVTILKRRKEAGKVDSMQTVGNVQGYTCVIVDDMVDTAGTLCKACDLL 275
Query: 237 REAGANKIYAFLTHGIFAGNAIEKINN-SSLEAIVVTNTIPQEKNMKLCPKLQTIDISVM 295
+E GA ++ A +HGI A ++IN +LE +VV+++I Q C KL + + +
Sbjct: 276 KEMGATRVIACASHGILTDPACDRINACEALEEVVVSDSIDQRLTTAKCDKLTVLTTAPL 335
Query: 296 LAEAIRRTHYAESVSYLFTNV 316
LA+A+ H S+S LF +
Sbjct: 336 LAQAVHSLHTEASLSSLFVKL 356
>UniRef50_Q1DW45 Cluster: Ribose-phosphate pyrophosphokinase; n=11;
Ascomycota|Rep: Ribose-phosphate pyrophosphokinase -
Coccidioides immitis
Length = 509
Score = 238 bits (582), Expect = 2e-61
Identities = 109/198 (55%), Positives = 148/198 (74%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGC 60
M +++F+G+SHP + + I RLG + +KFSN ET V IG SVR +DV+IVQSG
Sbjct: 1 MRGVQIFSGTSHPALTEAICERLGTVPAKCELRKFSNGETCVNIGVSVRNQDVFIVQSGS 60
Query: 61 GEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAG 120
+IND++MEL IMI+ACK SA +TAV+P FPYSRQ KK+ R ITA++LANL+S+AG
Sbjct: 61 SKINDSVMELLIMISACKGGSAKSITAVLPYFPYSRQSKKKSHRGAITARMLANLLSIAG 120
Query: 121 ADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTG 180
DHVIT+DLHASQ+QGFF PVDNL+AE I +WI+ N+P W +V+V+ +AGG KR+T
Sbjct: 121 VDHVITVDLHASQMQGFFGKPVDNLFAESLIARWIRINVPRWHEAVVVTKNAGGSKRVTS 180
Query: 181 IADRLDIDFAIIHKERQR 198
+AD L ++F I+ +R+R
Sbjct: 181 LADALKLNFGIVTTDRRR 198
Score = 98.3 bits (234), Expect = 2e-19
Identities = 47/120 (39%), Positives = 77/120 (64%), Gaps = 3/120 (2%)
Query: 197 QRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEAL-REAGANKIYAFLTHGIFAG 255
Q +N + LVGDV++KT +VDD+ D + + AE + ++ GANK+Y THG+F
Sbjct: 386 QNSNHERTITLVGDVRDKTVFIVDDMIDRAGSWIAAAETVVKKGGANKVYCIATHGLFGE 445
Query: 256 NAIEKINNSS-LEAIVVTNTIPQE-KNMKLCPKLQTIDISVMLAEAIRRTHYAESVSYLF 313
N++E++ ++ +V+TNT P + + + KL +D+S +L+E+IRR HY ES+S LF
Sbjct: 446 NSLEQMERCDCIDYVVITNTFPIDPQRARRMKKLVVLDVSALLSESIRRHHYGESISSLF 505
>UniRef50_Q8D2K5 Cluster: PrsA protein; n=1; Wigglesworthia
glossinidia endosymbiont of Glossina brevipalpis|Rep:
PrsA protein - Wigglesworthia glossinidia brevipalpis
Length = 305
Score = 236 bits (578), Expect = 5e-61
Identities = 120/299 (40%), Positives = 189/299 (63%), Gaps = 4/299 (1%)
Query: 4 IKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEI 63
+K+F+GSS+ ++ I LG+++ + KF + E N++I E+VRGE+V+I+QS C +
Sbjct: 1 MKIFSGSSNIKLSNKIANLLGISISNSEINKFQDGEINIKINENVRGEEVFIIQSMCFPV 60
Query: 64 NDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKK-EKSRAPITAKLLANLISVAGAD 122
NDN MEL I +A K ASA ++ AV+P YSRQD++ + PITAK++ANL++ +G
Sbjct: 61 NDNFMELVITADALKRASAKKIIAVIPYLGYSRQDRRVYNEQVPITAKMIANLLAASGIC 120
Query: 123 HVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIA 182
HVI +DLH QIQGFF+I +D++ E I + V+VSPD GG+KR+ I+
Sbjct: 121 HVIIVDLHCEQIQGFFDIILDSITTENIFFNDIISQ--KLNQPVLVSPDFGGMKRVRRIS 178
Query: 183 DRLD-IDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGA 241
L+ D II K R + NE + ++GDV N+ I++DD+ DT T+ K A L++ GA
Sbjct: 179 KMLNHKDIVIIEKYRPKLNESEVIKVIGDVNNRDCILLDDIIDTASTLCKSALCLKKLGA 238
Query: 242 NKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAI 300
+KI + TH +F+ + + I NS ++ +V ++IP N+K K++ + IS +LA+ I
Sbjct: 239 SKIICYATHPVFSKKSYKNIKNSEIDEFIVCDSIPLNVNIKCFNKIRVLTISKILADHI 297
>UniRef50_Q3M5L4 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Anabaena variabilis ATCC 29413|Rep: Ribose-phosphate
pyrophosphokinase - Anabaena variabilis (strain ATCC
29413 / PCC 7937)
Length = 310
Score = 235 bits (574), Expect = 1e-60
Identities = 121/314 (38%), Positives = 195/314 (62%), Gaps = 5/314 (1%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGC 60
M N +F G+++PD+A T+ +L + LG++ ++F + E NV + ESVR + V+I+QS
Sbjct: 1 MDNFILFAGTANPDLAGTVAQKLDIPLGKSAVERFPDGEVNVRLLESVRQKSVFILQSTA 60
Query: 61 GEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAG 120
+ND+L+EL +AC+ A+ASR+TA++P F Y+R DK+ R PITA ++A ++ G
Sbjct: 61 PPVNDHLVELLAFADACRRAAASRITAIIPYFGYARADKRHGRREPITASMVAEVLQAVG 120
Query: 121 ADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTG 180
+HV+T+DLH QI+GFF IPVD+L A P + I+ +P + V+VSPD G V+ T
Sbjct: 121 VNHVVTLDLHTLQIEGFFRIPVDSLTAVPIFCEAIRHYLP--PNFVVVSPDTGRVQMATQ 178
Query: 181 IADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAG 240
A +LD ++HK R E + T +VGDVK +++DD+ T T+ K EAL +A
Sbjct: 179 YAQKLDSSVVVLHKHRTSGTETEVTRVVGDVKGYACLIIDDMISTGGTLAKSIEALLKAE 238
Query: 241 AN-KIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEA 299
A +I THG+F A K+++ S++AI VT+++ ++ +L+ + I+ ++A
Sbjct: 239 ARPEIIIAATHGLFVKEARAKLSHPSVKAIFVTDSVTSKETD--WQQLKIVSIAPLVATT 296
Query: 300 IRRTHYAESVSYLF 313
I+R S+S LF
Sbjct: 297 IQRFKTDGSISDLF 310
>UniRef50_A7TNR7 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 433
Score = 235 bits (574), Expect = 1e-60
Identities = 105/201 (52%), Positives = 152/201 (75%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGC 60
M + KVF G+SHP++ + RLG+ KKF N ET+V+IG SVR EDVY++QS
Sbjct: 1 MRDYKVFIGNSHPELGNLVCQRLGVEPAPCVLKKFVNGETSVQIGVSVRDEDVYVIQSSS 60
Query: 61 GEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAG 120
+ND++MEL IM++A SA +VTAV+P FPYS+Q K +K R ITA++LANL+ +AG
Sbjct: 61 NTLNDHIMELLIMVSAFSGGSAGKVTAVIPMFPYSKQSKMKKHRGAITARMLANLLIMAG 120
Query: 121 ADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTG 180
ADHVI++DLH+SQ+QGFF+ PVDNLY P++ +WIKEN+ +++++V+VS + GG KR+T
Sbjct: 121 ADHVISMDLHSSQMQGFFSKPVDNLYGGPSLARWIKENVEDYENAVVVSKNPGGTKRVTA 180
Query: 181 IADRLDIDFAIIHKERQRANE 201
+AD L I+FA+IH +R+R+ +
Sbjct: 181 LADSLKINFAMIHTDRRRSKD 201
Score = 92.3 bits (219), Expect = 1e-17
Identities = 46/113 (40%), Positives = 74/113 (65%), Gaps = 3/113 (2%)
Query: 207 LVGDVKNKTAIMVDDLADTCDTILKGAEAL-REAGANKIYAFLTHGIFAGNAIEKINNS- 264
LVG V+N +AI++DD+ D + + AE L + GA K+Y THG+F G+ ++++ S
Sbjct: 318 LVGSVENSSAIILDDMIDRPTSFVSAAEHLVQNCGAKKVYVIATHGVFIGDCLQQLEQSE 377
Query: 265 SLEAIVVTNTIPQEK-NMKLCPKLQTIDISVMLAEAIRRTHYAESVSYLFTNV 316
++ IVVTN+ P K ++++ KL+ ID+S + AE IRR H ES+S LF ++
Sbjct: 378 AIHKIVVTNSYPIPKEHIEMSTKLEVIDVSAIFAECIRRDHNGESISVLFDSL 430
>UniRef50_A0CY99 Cluster: Chromosome undetermined scaffold_31, whole
genome shotgun sequence; n=2; Oligohymenophorea|Rep:
Chromosome undetermined scaffold_31, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 394
Score = 232 bits (567), Expect = 1e-59
Identities = 125/322 (38%), Positives = 194/322 (60%), Gaps = 11/322 (3%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGE 62
N + +G+S+ ++A+ I L + LG T +F++ E +++ +++RG+DV+I+QS
Sbjct: 69 NTIILSGNSNKELAEEIAEYLNIKLGSVTIGRFADGECQIQVLDNIRGKDVFIIQSTSPP 128
Query: 63 INDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGAD 122
+NDNLMEL ++++A + ASA ++ VVP + Y+RQD+K R PI+A +A L+ G D
Sbjct: 129 VNDNLMELLLLVSALRRASARKIIVVVPYYGYARQDRKCAPRVPISAADVARLLETVGVD 188
Query: 123 HVITIDLHASQIQGFF--NIPVDNLYAEPAITKWIK-ENIPEWKSSVMVSPDAGGVKRMT 179
+I++DLH QIQGFF +PVDNL A ++ + E+K +VSPDAGGV R
Sbjct: 189 RLISVDLHCGQIQGFFGPRVPVDNLEANLVAQNYLSLQKKYEFKDVAIVSPDAGGVYRAK 248
Query: 180 GIADRLD-------IDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKG 232
++ D A+I K+R+ + S LVG VK K I+VDD+ DT T+ +
Sbjct: 249 KFQEQFDQHHPGMQSHLAMIIKQREGPGKIASMNLVGQVKGKDCIIVDDIIDTAGTLSEA 308
Query: 233 AEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMK-LCPKLQTID 291
A L+E GA +++AF TH +F+G A + L+ I+VTNTIP + + L K+ +
Sbjct: 309 ARVLKEQGAKRVFAFATHALFSGKAFAHLGAPFLDQIIVTNTIPSKPQEEVLGDKICRLS 368
Query: 292 ISVMLAEAIRRTHYAESVSYLF 313
++ +LAEAI R ESVS LF
Sbjct: 369 VAPLLAEAIYRVQKKESVSTLF 390
>UniRef50_Q8G5P2 Cluster: Ribose-phosphate pyrophosphokinase; n=56;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Bifidobacterium longum
Length = 340
Score = 231 bits (565), Expect = 2e-59
Identities = 127/319 (39%), Positives = 187/319 (58%), Gaps = 5/319 (1%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGE 62
N+ + TG HP +A+ + +LG+++ T F+N E V ESVRG DV+++QS
Sbjct: 13 NLILVTGRIHPKLAEDVAEQLGIDVLETTAYDFANGEMYVRYTESVRGADVFVLQSHYKP 72
Query: 63 INDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGAD 122
IN +ME IMI+A K ASA +TAV P YSRQDKK + R PI+ +L+ +L+ AGAD
Sbjct: 73 INKAIMEQLIMIDALKRASARSITAVCPLLGYSRQDKKHRGREPISCRLVFDLLKTAGAD 132
Query: 123 HVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSV-MVSPDAGGVKRMTGI 181
++++DLHA+Q QGFF+ PVD+L A P + +I++ +V +VSPDAG ++
Sbjct: 133 RIMSVDLHAAQSQGFFDGPVDHLVAMPVLVDYIRDRFQGHLDNVAVVSPDAGRIRVAEQW 192
Query: 182 ADRL-DIDFAIIHKERQ--RANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALRE 238
A RL A +HK R R N+ + +VGDV K ++VDDL DT TI L++
Sbjct: 193 AQRLGGGPLAFVHKTRDITRPNQAVANRVVGDVAGKDCVLVDDLIDTAGTIAGACHVLQD 252
Query: 239 AGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAE 298
AGA + THG+ +G A+E++ N +V+T+T+P + K L + I+ +LA
Sbjct: 253 AGAKSVTVVATHGVLSGPAVERLKNCGAREVVLTDTVPIPEE-KRWDGLTVLSIAPLLAS 311
Query: 299 AIRRTHYAESVSYLFTNVP 317
AIR SV+ LF P
Sbjct: 312 AIRAVFEDGSVAELFDTYP 330
>UniRef50_P75044 Cluster: Ribose-phosphate pyrophosphokinase; n=6;
Mycoplasma|Rep: Ribose-phosphate pyrophosphokinase -
Mycoplasma pneumoniae
Length = 328
Score = 231 bits (564), Expect = 2e-59
Identities = 127/316 (40%), Positives = 185/316 (58%), Gaps = 6/316 (1%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGE 62
N VF+ S D+ I +L + +G T +F++ ET + ESVR +DV+I QS C
Sbjct: 5 NHVVFSLSKTHDLVSRICQKLKMPMGLITHNEFADGETYIRFEESVRNKDVFIFQSTCAP 64
Query: 63 INDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGAD 122
+ND+LMEL I I+A K SA +TA++P + Y+RQD+K R PIT+KL+A+L++ AG
Sbjct: 65 VNDSLMELLIAIDALKRGSAKSITAILPYYGYARQDRKTMGREPITSKLVADLLTTAGVS 124
Query: 123 HVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIA 182
V D+H+ Q QGFFNIPVD L E + + K V+VSPD GGVKR IA
Sbjct: 125 RVALTDIHSDQTQGFFNIPVDTLRTYHVFLTRTVELLGK-KDLVVVSPDYGGVKRARLIA 183
Query: 183 DRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGAN 242
L++ AII K R N +S ++G+V NK ++VDD+ DT T++ A+ LRE A
Sbjct: 184 TSLELPLAIIDKRRPAHNVAESINVLGEVANKNCLIVDDMIDTGGTVIAAAKLLREHHAK 243
Query: 243 KIYAFLTHGIFAGNAIEKINNSSLEAIV----VTNTIPQEKNMKLCPKLQTIDISVMLAE 298
K+ THG+F G A ++ + E +V V+N+IPQ K CP+ Q ID++ + E
Sbjct: 244 KVCVMATHGLFNGEAPQRFQKAFNEGLVDYLFVSNSIPQTK-FDQCPQFQVIDLAPLFEE 302
Query: 299 AIRRTHYAESVSYLFT 314
+ S+S ++T
Sbjct: 303 VLLCYANNSSISAIYT 318
>UniRef50_Q4Q0M2 Cluster: Phosphoribosylpyrophosphate synthetase,
putative; n=6; Trypanosomatidae|Rep:
Phosphoribosylpyrophosphate synthetase, putative -
Leishmania major
Length = 358
Score = 230 bits (563), Expect = 3e-59
Identities = 120/315 (38%), Positives = 195/315 (61%), Gaps = 8/315 (2%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGE 62
+++V G+++P +A+ + L + + + F+N ET V+I ES+RG+D++++Q C
Sbjct: 10 SLRVVHGNANPKLAEDVCRYLNIPVTASRVGSFANGETIVKILESIRGDDIFVIQPTCSN 69
Query: 63 -----INDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLIS 117
+N +MEL ++I+ K++SA RV AV+P + Y+RQD+K R PI+A +A +++
Sbjct: 70 SAGTNVNQAVMELLLIIHTLKLSSARRVIAVIPHYGYARQDRKHTGRVPISASAVARMVT 129
Query: 118 VAGADHVITIDLHASQIQGFFN-IPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVK 176
G + V+T+DLH QIQGFF+ PV +L +++K+ + V+V+PDAG V
Sbjct: 130 EMGVNGVVTMDLHCGQIQGFFHGCPVADLSPSSEFAEYVKQKNFTPNNLVVVAPDAGAVN 189
Query: 177 RMTGIADRLDID-FAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEA 235
R + DR+ I K R AN+ DS LVG+V I+VDD+ DT T+ K AE
Sbjct: 190 RARRMCDRIGASRIVTILKRRVVANQVDSMQLVGEVDECVCIIVDDMIDTAGTLCKAAEV 249
Query: 236 LREAGANKIYAFLTHGIFAGNAIEKINN-SSLEAIVVTNTIPQEKNMKLCPKLQTIDISV 294
L+E GA +++A+ THGIF A E++ +L +VVT++IPQE++ + C K++ I I+
Sbjct: 250 LKEYGAKEVHAYATHGIFTDPACERLTQCDALVEVVVTDSIPQEESCQKCKKIKVISIAK 309
Query: 295 MLAEAIRRTHYAESV 309
+LA+AI R H ES+
Sbjct: 310 LLADAIYRMHSEESL 324
>UniRef50_A7EV32 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 526
Score = 229 bits (560), Expect = 7e-59
Identities = 104/198 (52%), Positives = 145/198 (73%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGC 60
M N +F GSS P + I LG+ +F+N ET+V+I S+R +DV++VQSG
Sbjct: 1 MRNTLIFAGSSCPKLTDQICTNLGMAAAPVELTQFANGETSVKIMTSIREKDVFVVQSGS 60
Query: 61 GEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAG 120
+IND++MEL IMI+ACK SA+++TAV+P FPYSRQ KK+ R ITA++LANL+ VAG
Sbjct: 61 SKINDSIMELLIMISACKGGSANKITAVLPYFPYSRQSKKKSHRGAITARMLANLLHVAG 120
Query: 121 ADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTG 180
+HVIT+DLHASQ+QGFF PVDNL+AEP I +WI+ N+PEW +V VS +AGG KR+T
Sbjct: 121 INHVITVDLHASQMQGFFKCPVDNLHAEPLIARWIRRNVPEWNEAVCVSKNAGGTKRVTS 180
Query: 181 IADRLDIDFAIIHKERQR 198
+AD L ++F ++ +++R
Sbjct: 181 LADALKLNFGMVTTDKRR 198
Score = 106 bits (254), Expect = 9e-22
Identities = 55/113 (48%), Positives = 77/113 (68%), Gaps = 5/113 (4%)
Query: 207 LVGDVKNKTAIMVDDLADTCDTILKGAEAL-REAGANKIYAFLTHGIFAGNAIEKINNSS 265
LVGDV+N+T +VDD+ D + + AE + + GA K+Y THG+F GNA+E++ N
Sbjct: 412 LVGDVRNRTVFIVDDMIDKAGSWIAAAETVVKRGGAKKVYCIATHGLFGGNALEELQNCD 471
Query: 266 -LEAIVVTNT--IPQEKNMKLCPKLQTIDISVMLAEAIRRTHYAESVSYLFTN 315
++ IVVTN+ IP EK K KLQ +D+S +L+EAIRR HY ES+S LFT+
Sbjct: 472 CIDMIVVTNSFPIPPEK-AKDAKKLQILDLSKLLSEAIRRNHYGESISALFTH 523
>UniRef50_Q6CG51 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Yarrowia lipolytica|Rep: Ribose-phosphate
pyrophosphokinase - Yarrowia lipolytica (Candida
lipolytica)
Length = 370
Score = 227 bits (555), Expect = 3e-58
Identities = 113/216 (52%), Positives = 156/216 (72%), Gaps = 10/216 (4%)
Query: 111 LLANLISVAGADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSP 170
L+A+L++ AGADH+IT+DLH Q QGFF+IPVDNLY +P + +I IP ++ +V+VSP
Sbjct: 154 LIASLLTCAGADHIITMDLHDPQFQGFFDIPVDNLYGKPLLQHYISTQIPNYQDAVIVSP 213
Query: 171 DAGGVKRMTGIADRLDIDFAIIHKERQRAN-EGD--------STVLVGDVKNKTAIMVDD 221
DAGG KR T IAD L +DFA+IHKER+ GD +T+LVGDV + AI++DD
Sbjct: 214 DAGGAKRATAIADGLCMDFALIHKERRPTKISGDHIAGKHNATTMLVGDVSGRVAILIDD 273
Query: 222 LADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKN- 280
L DT +TI + A+ L++ GA K+YA +THG+F+G+A+EKI S ++ IV TN+ PQ+++
Sbjct: 274 LLDTSNTITRAAKLLKDQGAVKVYALITHGVFSGDAVEKIKKSEIDKIVTTNSTPQDQHA 333
Query: 281 MKLCPKLQTIDISVMLAEAIRRTHYAESVSYLFTNV 316
++L KL IDIS + AEAIRR H ESVS LF +V
Sbjct: 334 VELGEKLDVIDISRVFAEAIRRIHNGESVSMLFDHV 369
Score = 117 bits (282), Expect = 3e-25
Identities = 54/97 (55%), Positives = 69/97 (71%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGC 60
M + +F+GSSHP + + I A L + KF N ET+V I +SVR +DVY+VQSGC
Sbjct: 1 MRSATIFSGSSHPKLVERICANLAIEPSNVDLAKFKNGETSVTIRDSVREKDVYVVQSGC 60
Query: 61 GEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQ 97
G +NDN +EL IMI+ACK ASA +VTAV+P FPYSRQ
Sbjct: 61 GHVNDNFIELLIMISACKTASAKKVTAVMPLFPYSRQ 97
>UniRef50_Q4QI56 Cluster: Phosphoribosylpyrophosphate synthetase;
n=8; Trypanosomatidae|Rep: Phosphoribosylpyrophosphate
synthetase - Leishmania major
Length = 370
Score = 223 bits (545), Expect = 5e-57
Identities = 125/316 (39%), Positives = 189/316 (59%), Gaps = 12/316 (3%)
Query: 8 TGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCG----EI 63
+G+ + +A+ + +G + + ++SN E NV I E V G DVYI+QS G +I
Sbjct: 51 SGNGNRPLAEAVALLMGTHTHHTSVTQYSNGEVNVRINECVLGADVYIIQSTTGNEIIDI 110
Query: 64 NDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADH 123
N LMEL ++I ++++A VT + P F Y+RQD+K R PI+A ++A ++ G +
Sbjct: 111 NTALMELLLLIRKMRLSNAKSVTVIAPFFGYARQDRKTSLRGPISASVVARMVVKMGVNR 170
Query: 124 VITIDLHASQIQGFF-NIPVDNLYAEPAITKWIKENIPEW---KSSVMVSPDAGGVKRMT 179
+ ++DLH++QIQGFF NIPVDNL +++ + W V+VSPDAGGV+R
Sbjct: 171 LASLDLHSNQIQGFFDNIPVDNLLMAHEFARYLHDQ--PWFNVDQMVVVSPDAGGVERAK 228
Query: 180 GIADRLDID-FAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALRE 238
+AD L + I K R A + D+ VG+V T I+VDD+ DT T++K E L+E
Sbjct: 229 QLADILQVGRIVTIVKRRIAAGKVDTMQSVGEVAGFTCIIVDDMIDTGGTLVKACELLKE 288
Query: 239 AGANKIYAFLTHGIFAGNAIEKINN-SSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLA 297
GA ++ A THGI ++INN S+LE +VV+++IPQE++ K PKL + I+ ++A
Sbjct: 289 LGAVRVMACCTHGILTNPCSDRINNCSALEQLVVSDSIPQEEHQKAIPKLTVLTIAPLIA 348
Query: 298 EAIRRTHYAESVSYLF 313
I R ESVS LF
Sbjct: 349 AVIHRYLNEESVSSLF 364
>UniRef50_Q822W0 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
Chlamydophila|Rep: Ribose-phosphate pyrophosphokinase -
Chlamydophila caviae
Length = 301
Score = 223 bits (544), Expect = 6e-57
Identities = 117/296 (39%), Positives = 189/296 (63%), Gaps = 6/296 (2%)
Query: 6 VFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEIND 65
+ +GSS+ +A+ + A L + LGR +F + ET+V++ E VRG DV+I+QS G+ N
Sbjct: 7 LLSGSSNLILAQNVCAELKIKLGRMELNQFPDGETHVKVLEDVRGRDVFIMQSIVGQPNH 66
Query: 66 NLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVI 125
L EL I+ +A K +SA +TA++P Y RQD++ K+ PITAKL+A++++ AG ++I
Sbjct: 67 YLFELLIIADALKRSSAKSITAIIPYLGYCRQDRRNKTGEPITAKLVADVLTTAGITNLI 126
Query: 126 TIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRL 185
T DLHA QI+GF+ VD+L+ + IK I + + ++PD G +K IA L
Sbjct: 127 TCDLHADQIEGFYKTHVDHLHCQQLFVDTIKSCISQ--DCIAIAPDIGSIKIAERIARML 184
Query: 186 DIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIY 245
D A+I KER + E S L+G+V++K +++DDL T +T+++ A ++ GA KI
Sbjct: 185 DTGLAVIKKERLNSFE-VSMQLIGEVQDKNVVIIDDLCSTANTLVEAANLCKQKGAKKII 243
Query: 246 AFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIR 301
A +THG+F G+AI+KI S+LE++ VT+TI ++ C ++T+ + M+A AI+
Sbjct: 244 ATVTHGLFVGDAIQKIETSALESLFVTDTI-HLQSTSTC--IKTLSTAPMIASAIK 296
>UniRef50_Q8EUI1 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Mycoplasma penetrans|Rep: Ribose-phosphate
pyrophosphokinase - Mycoplasma penetrans
Length = 332
Score = 220 bits (537), Expect = 4e-56
Identities = 117/304 (38%), Positives = 182/304 (59%), Gaps = 8/304 (2%)
Query: 16 AKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMIN 75
AK + + + LG T KF++ E V+ +VRG V++ QS C +NDNLMEL I I+
Sbjct: 20 AKEVAEKTNIQLGTIKTSKFADGEILVKSNSTVRGMHVFLFQSTCNPVNDNLMELLIAID 79
Query: 76 ACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQ 135
+ K ASA +T ++P F Y+RQD+K K R PIT KL+AN + AGA VI ID+H+ Q Q
Sbjct: 80 SLKRASAKTITVIIPYFGYARQDRKAKGREPITCKLVANFLEGAGATKVILIDIHSEQTQ 139
Query: 136 GFFNIPVDNLYAEPAITKWIKENIPE-WKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHK 194
GFF+IPVD L A + ++N P K+ +V+PD G VK + I + L+++ AI+ K
Sbjct: 140 GFFDIPVDTLTASCVLFNEFRKNNPSVIKNLTVVAPDYGAVKNVRKITETLNLNLAIMDK 199
Query: 195 ERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFA 254
R + N + + ++GDV + +++DD+ DT TIL+ E L+E G KI+ THG+F+
Sbjct: 200 RRPQPNVVEISNVLGDVMGRDCLLLDDMIDTGGTILQNIELLKERGCKKIFVMATHGVFS 259
Query: 255 GNAIEK----INNSSLEAIVVTNTIPQEKNMKL-CPKLQTIDISVMLAEAIRRTHYAESV 309
A+EK ++ ++ + V +TI E N K+ P ++ + +S AE + +SV
Sbjct: 260 NGALEKFKLALDKGLIDQLYVADTI--EANTKIEHPNIKVVSLSNFYAEILDAQINHKSV 317
Query: 310 SYLF 313
S ++
Sbjct: 318 SKIY 321
>UniRef50_Q74LT0 Cluster: Phosphoribosylpyrophosphate synthetase;
n=5; Lactobacillus|Rep: Phosphoribosylpyrophosphate
synthetase - Lactobacillus johnsonii
Length = 329
Score = 220 bits (537), Expect = 4e-56
Identities = 123/302 (40%), Positives = 179/302 (59%), Gaps = 7/302 (2%)
Query: 15 IAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMI 74
+A+ I A L L + FS+ E V I ESVRG DVY++QS +N+N MEL I++
Sbjct: 24 LAERIAAALDKPLLETAVQHFSDGEIQVNITESVRGCDVYVIQSIQDPVNENFMELMIVL 83
Query: 75 NACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQI 134
+A ASA V V+P YSRQD K +SR PITAKLLANL+ + D +I +DLHASQI
Sbjct: 84 DALHRASAHSVNVVIPYMAYSRQDTKNRSREPITAKLLANLLQLTDIDDLIAVDLHASQI 143
Query: 135 QGFFNIPVDNLYAEPAITKWIKEN---IPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAI 191
QGF+NIPVD+L+A P + ++ +N E V+VSPD G K + D AI
Sbjct: 144 QGFYNIPVDHLHAMPILAQYFLDNGIASKENDDVVVVSPDHSGAKLVRTFGSYFDAPIAI 203
Query: 192 IHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHG 251
+ +R + ++ ++GDVK+KT I+VDDL DT I ++ AGA K+Y TH
Sbjct: 204 V-DQRGARYDAEAHDMIGDVKDKTVIIVDDLIDTGSRIASSTRSVLAAGAKKVYVAATHA 262
Query: 252 IFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRRTHYAESVSY 311
+ + NAI+ +N +E IVVT+TI K+ K ++ + ++ +LA+ I + +S+
Sbjct: 263 LLSQNAIDVLNELPVEQIVVTDTI---KHKKYPDRMVRLSVARLLAKGIDYIYNDKSIHQ 319
Query: 312 LF 313
+F
Sbjct: 320 IF 321
>UniRef50_Q03YB5 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
Lactobacillales|Rep: Ribose-phosphate pyrophosphokinase
- Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 323
Score = 215 bits (525), Expect = 1e-54
Identities = 112/310 (36%), Positives = 180/310 (58%), Gaps = 5/310 (1%)
Query: 2 PNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCG 61
P ++F S+ ++A I LG+ L K F++ E I +VRG +VY++Q
Sbjct: 3 PAYELFNLGSNDELAGEISTILGVPLAPIDIKTFADNEIYERIENTVRGRNVYVIQGITA 62
Query: 62 EINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGA 121
+NDN M+L I I+A + ASA+ + ++P F Y+R D+K +SR PI+A+++AN++ G
Sbjct: 63 PVNDNFMKLMIFIDAARRASANSINVIIPYFGYARSDRKARSREPISARMIANMLESQGV 122
Query: 122 DHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGI 181
V+T+DLHA Q+QGFF+IPVD+L A PA+ + N V+V+PD V R
Sbjct: 123 KRVMTMDLHADQVQGFFDIPVDHLLAMPALGHYFYANDLLGDDLVVVAPDHSSVARARKF 182
Query: 182 ADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGA 241
A L D+A++ + + G+V K AI++DD+ DT +++ +EA AGA
Sbjct: 183 AKLLHADWALVDRRVDSVRPNTPYQITGNVAGKRAILIDDIIDTGTSMVLASEAAANAGA 242
Query: 242 NKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNT--IPQEKNMKLCPKLQTIDISVMLAEA 299
+IYA TH + + NA++ + + ++ +VV NT I + KNM KL+ + ++ AEA
Sbjct: 243 IEIYAVATHAVLSDNAVDHLEKAPIDHVVVANTVEIAEHKNMS---KLKVLSVAESFAEA 299
Query: 300 IRRTHYAESV 309
IRR + ES+
Sbjct: 300 IRRINVFESI 309
>UniRef50_Q6F241 Cluster: Ribose-phosphate pyrophosphokinase; n=6;
Mollicutes|Rep: Ribose-phosphate pyrophosphokinase -
Mesoplasma florum (Acholeplasma florum)
Length = 347
Score = 213 bits (520), Expect = 5e-54
Identities = 117/324 (36%), Positives = 194/324 (59%), Gaps = 12/324 (3%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGE 62
N+ +F + ++A+ I LG+ T KF++ E +E +SVRG++++++QS
Sbjct: 7 NVHIFGLTQGVELAQEICDILGVKRKEVKTLKFADGEILIESLDSVRGKEIFVIQSTSTP 66
Query: 63 INDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGAD 122
+N+++MEL I I+A K SA ++ V+P + Y+RQD+K K R PIT+KL+A+L++ AGAD
Sbjct: 67 VNESIMELLIAIDAFKRGSAEKINVVIPYYGYARQDRKAKGRQPITSKLVADLLTKAGAD 126
Query: 123 HVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIP--EWKSS--VMVSPDAGGVKRM 178
V++ID+H+ Q GFF++P+DN Y + I + I W S ++VSPD GG+ R+
Sbjct: 127 RVMSIDIHSPQSMGFFDVPMDNFYTAQTLATEIIDTIELNNWDPSNCILVSPDYGGMTRV 186
Query: 179 TGI---ADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEA 235
+ + A+I K R N+ + ++GD+K+K ++DD+ DT TI+ A+A
Sbjct: 187 HKVESYTGGVTNGIAVIGKRRPEPNKAEVEFVLGDIKDKHCFIIDDMIDTGGTIINAAKA 246
Query: 236 LREAGANKIYAFLTHGIFAGNAIEK----INNSSLEAIVVTNTIPQEKNMKLCPKLQTID 291
L+E GA ++ F HG+F G A E+ I +E +VVTNTI Q + K L+ I
Sbjct: 247 LKEQGAKDVHIFACHGLFNGPAKERMEAAIKEKIVEEVVVTNTI-QIADEKKFNGLKIIS 305
Query: 292 ISVMLAEAIRRTHYAESVSYLFTN 315
++ +LAE I + ES++ ++ N
Sbjct: 306 VAPLLAEMIDSSISHESLTEVYNN 329
>UniRef50_Q8X022 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
Pezizomycotina|Rep: Ribose-phosphate pyrophosphokinase -
Neurospora crassa
Length = 431
Score = 212 bits (518), Expect = 9e-54
Identities = 106/227 (46%), Positives = 158/227 (69%), Gaps = 24/227 (10%)
Query: 111 LLANLISVAGADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSP 170
L+ANL++ AG DHVIT+DLH Q+QGFF+IPVDNLY +P + ++I+++IP W+ +V++SP
Sbjct: 202 LVANLLTCAGCDHVITMDLHDPQVQGFFDIPVDNLYGQPLLKRYIQQHIPNWRDAVIISP 261
Query: 171 DAGGVKRMTGIADRLDIDFAIIHK-------------------ERQRANEGD----STVL 207
DAGG KR T IAD L ++FA+IHK ER+ D S +L
Sbjct: 262 DAGGAKRATAIADSLGMEFALIHKVNALLQISPPGLPLNQESQERRPTKITDRQNASMML 321
Query: 208 VGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLE 267
VG+V ++ I++DD+ADT +TI + A+ L++ GA IYA LTHG+F+G+AI ++ S+++
Sbjct: 322 VGNVTDRVCILLDDIADTGNTITRAAKLLKKEGATTIYALLTHGVFSGDAISRVKASAID 381
Query: 268 AIVVTNTIPQEKNMK-LCPKLQTIDISVMLAEAIRRTHYAESVSYLF 313
+VVTN++PQ+++ K L KL +DIS + AEA+RR H+ ES+S LF
Sbjct: 382 KLVVTNSVPQDEHKKQLGSKLDVLDISPIFAEAMRRVHHGESISVLF 428
Score = 101 bits (241), Expect = 3e-20
Identities = 52/99 (52%), Positives = 68/99 (68%), Gaps = 4/99 (4%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCG- 61
NI V G+SHP++ ++I LGL KFS+ E+ EI +SVRG+DVYI+Q+G G
Sbjct: 4 NIVVLGGNSHPELVESICGILGLPACSRILTKFSSGESRCEIQDSVRGKDVYIIQTGFGG 63
Query: 62 ---EINDNLMELFIMINACKIASASRVTAVVPCFPYSRQ 97
+ND+ M+L IMI+ACK SA RVTAV+P FPYSRQ
Sbjct: 64 NGSRLNDHFMDLCIMISACKTGSARRVTAVLPLFPYSRQ 102
>UniRef50_Q0G092 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Fulvimarina pelagi HTCC2506|Rep: Ribose-phosphate
pyrophosphokinase - Fulvimarina pelagi HTCC2506
Length = 307
Score = 210 bits (513), Expect = 4e-53
Identities = 106/232 (45%), Positives = 154/232 (66%), Gaps = 2/232 (0%)
Query: 23 LGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMINACKIASA 82
L L +G A ++F+++E VEI E+VRGEDV++VQS ND+LMEL I+I+A + ASA
Sbjct: 5 LELPVGEALVRRFADQEIFVEIQENVRGEDVFVVQSTSYPANDHLMELLIIIDAMRRASA 64
Query: 83 SRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFFNIPV 142
R+TAV+P F Y+RQD+K R PI+AKL+ANLI+ AGAD V+T+DLHA QIQGFF+IP
Sbjct: 65 RRITAVLPYFGYARQDRKAGGRTPISAKLVANLITHAGADRVMTLDLHAGQIQGFFDIPT 124
Query: 143 DNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEG 202
DNL+A P + IKE+ + + +VSPD GGV R +A RLD AI+ K R+R E
Sbjct: 125 DNLFAIPLFARDIKEH-QDLSNLTVVSPDVGGVVRARALAKRLDAQLAIVDKRRERPGES 183
Query: 203 DSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFA 254
+ ++GDV+ + I++DD+ D+ + + + ++THG+ +
Sbjct: 184 EVMNIIGDVEGRNCILIDDIIDSAARSAMRPQP-SSMPVRERFGYITHGVLS 234
>UniRef50_O62580 Cluster: Phosphoribosyl pyrophosphate synthetase;
n=2; Giardia intestinalis|Rep: Phosphoribosyl
pyrophosphate synthetase - Giardia lamblia (Giardia
intestinalis)
Length = 370
Score = 207 bits (506), Expect = 3e-52
Identities = 113/278 (40%), Positives = 169/278 (60%), Gaps = 6/278 (2%)
Query: 33 KKFSNKETNVEIGESVRGEDVYIVQSGCG-EINDNLMELFIMINACKIASASRVTAVVPC 91
K+FS+ E N++ ++RG D++IV + C NDNLMEL + I+A K ASA+ VTA++P
Sbjct: 41 KQFSDGEINLQYESNIRGCDLFIVGAICPPRCNDNLMELLLAIDAAKRASAAHVTAIIPY 100
Query: 92 FPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFF--NIPVDNLYAEP 149
F Y+RQD+K SR PI+AKL+ +L+ +G D V+ D+HA+QIQGFF +IP D++
Sbjct: 101 FGYARQDRKAASRTPISAKLVTDLLIASGVDRVVVQDIHAAQIQGFFPSSIPFDHIDGYL 160
Query: 150 AITKWIKENIPE-WKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLV 208
+ I + E K+ ++VSPDAGG R +A +L D AII K R AN D +V
Sbjct: 161 VFIQAIIDRFEEDIKNLIVVSPDAGGATRCRNLATQLHADIAIIDKRRVVANMCDVMNVV 220
Query: 209 GDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEA 268
GDV K ++ DD+ DT ++ K A+AL+E GA +++A +H + +G A KI S ++
Sbjct: 221 GDVNGKICLLYDDIVDTARSLTKAAQALKEKGAEQVFACASHAVLSGEATRKIKESCIDY 280
Query: 269 IVVTNTIPQEKNM--KLCPKLQTIDISVMLAEAIRRTH 304
I+ +++IP +L KLQ + M A I H
Sbjct: 281 ILFSDSIPLSPKQIEELGEKLQIVSGDFMFANCINCIH 318
>UniRef50_A0E424 Cluster: Chromosome undetermined scaffold_77, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_77,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 371
Score = 202 bits (494), Expect = 7e-51
Identities = 118/324 (36%), Positives = 189/324 (58%), Gaps = 20/324 (6%)
Query: 2 PNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCG 61
P VF+G+S+ +A + LG++LG+ ++F++ E N+++ E+VRG + +I+QS C
Sbjct: 43 PETIVFSGNSNTKLASEVAKCLGISLGKVLLERFADGECNIQVLENVRGRNAFIIQSTCP 102
Query: 62 EINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGA 121
+N+NL+ELF+ I+A + AS +T ++P + YSRQD K I A +A ++ G
Sbjct: 103 PVNENLVELFLFISALRRASVKTITVIIPYYGYSRQDHKLAKTESIAAADIAKILEQTGI 162
Query: 122 DHVITIDLHASQIQGFF--NIPVDNLYAEPAITKWIKENIPEWKSS-----VMVSPDAGG 174
DH+++IDLH Q+QG F ++PVDNL P IT + N K S +VSPD G
Sbjct: 163 DHLVSIDLHRGQLQGAFSTSVPVDNL--SPYITLIYELNNHPLKLSPPNELTLVSPDFNG 220
Query: 175 VKRMTGIADRL------DIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDT 228
V R+ + D L +I+ A+I+K + +E + + LVGDV K ++VDD+ D+ T
Sbjct: 221 VSRVKKVQDELRQELIGNIELAMIYKSKHPVSETEIS-LVGDVNGKNCLIVDDIIDSGRT 279
Query: 229 ILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMK---LCP 285
+ A+ L+ GA + A+ TH +F+G A + S+L I VT+TI Q K++ L
Sbjct: 280 LKNAADILKREGAKTVMAYGTHPVFSGKAALNLGISNLSKIYVTDTI-QVKDLDKQILHE 338
Query: 286 KLQTIDISVMLAEAIRRTHYAESV 309
KL + ++ +LAE I R ES+
Sbjct: 339 KLSVLSVAPLLAETIYRLQKRESL 362
>UniRef50_Q9EWS0 Cluster: Putative ribose-phosphate
pyrophosphokinase; n=9; Actinomycetales|Rep: Putative
ribose-phosphate pyrophosphokinase - Streptomyces
coelicolor
Length = 317
Score = 200 bits (488), Expect = 4e-50
Identities = 111/318 (34%), Positives = 181/318 (56%), Gaps = 4/318 (1%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGC 60
M +I VF+GS+HPD+A+ + A+LG+ L +F+N V++ + R DV++VQ
Sbjct: 1 MRDIAVFSGSAHPDLAEEVCAQLGVPLSPTRVSRFANDCLEVQLMANCRERDVFLVQPLV 60
Query: 61 GEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAG 120
+ ++L+EL +M +A + ASA R+T V+P + Y+R DKK+ R + +L+A+L+ AG
Sbjct: 61 TPVQEHLVELLMMCDAARGASAGRITVVMPHYSYARSDKKDAPRISLGGRLVADLLVAAG 120
Query: 121 ADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTG 180
A V+ + LH+ Q+ GFF++PVD+L+A + ++ + + +VSPD G K
Sbjct: 121 ASRVLAMTLHSPQVHGFFSVPVDHLHALRELAAHFRQY--DLSRATVVSPDLGNAKEAAA 178
Query: 181 IADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAG 240
A L A K+R + + ++GDV + I++DD T+L+ + LRE+G
Sbjct: 179 FARMLGAQVAAGAKQRYADDRVSISSVIGDVAGRDVIVLDDEIAKGSTVLELLDRLRESG 238
Query: 241 ANKIYAFLTHGIFAGNAIEKINNS-SLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEA 299
I THG+FA A+ +++ + IV TNT+P + KL+ + I+ LAEA
Sbjct: 239 PRTIRLACTHGLFAAGALGRLSEQPDVLEIVCTNTVPVPAD-DHTDKLRILSIAPALAEA 297
Query: 300 IRRTHYAESVSYLFTNVP 317
+RR H ESVS LF P
Sbjct: 298 VRRIHNGESVSALFDARP 315
>UniRef50_A7ARJ1 Cluster: Ribose-phosphate pyrophosphokinase,
putative; n=1; Babesia bovis|Rep: Ribose-phosphate
pyrophosphokinase, putative - Babesia bovis
Length = 339
Score = 199 bits (485), Expect = 9e-50
Identities = 109/307 (35%), Positives = 178/307 (57%), Gaps = 13/307 (4%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGE 62
N+ VFTG+ + + + GL LG++ FS+ E V++ E + G DV I+QS
Sbjct: 34 NLLVFTGNWNKCLVNDTCSLSGLTLGKSDVSTFSDGEIKVDLQEEILGCDVVIIQSTSPP 93
Query: 63 INDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGAD 122
+N NL+EL MI+A + + A ++TA++P F Y+RQD+K + I+A +A ++ + G D
Sbjct: 94 VNRNLIELLFMISAARKSGAKQITAIIPYFGYARQDRKPSPGSNISASDVARMLELTGVD 153
Query: 123 HVITIDLHASQIQGFF--NIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTG 180
VI+ DLH++ QGFF + VDNL ++ K +++ + +VSPDAG R
Sbjct: 154 RVISFDLHSAMCQGFFGPRVQVDNL----SVIKIFIDHLVGFNRVAVVSPDAGAYARSIQ 209
Query: 181 IAD-------RLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGA 233
+ D + D+ A+I K+R +ANE S L GDVK++ I+ DD+ DT T+ K A
Sbjct: 210 LYDIFTKKYPQCDVSSAMIFKQRLKANELASAQLCGDVKDRDVIIADDIVDTAGTLCKAA 269
Query: 234 EALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDIS 293
E L GA + A +THGIF+G A+++I S + I+ T++I +++ PK+Q I ++
Sbjct: 270 EILITNGAKSVTAVITHGIFSGPALQRIRESPITRILTTDSIAHSESVLAEPKIQIISLA 329
Query: 294 VMLAEAI 300
L+ +
Sbjct: 330 QELSRVL 336
>UniRef50_Q4UNC9 Cluster: Ribose-phosphate pyrophosphokinase; n=9;
Rickettsia|Rep: Ribose-phosphate pyrophosphokinase -
Rickettsia felis (Rickettsia azadi)
Length = 293
Score = 198 bits (484), Expect = 1e-49
Identities = 114/298 (38%), Positives = 178/298 (59%), Gaps = 8/298 (2%)
Query: 4 IKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEI 63
+K+ GSS+ +A + L + F++ E VEI ES EDV IVQS +
Sbjct: 1 MKILAGSSNKLLASRLAIALNIKYIEPRITYFNDSEIKVEIQESFHNEDVIIVQSTSKPV 60
Query: 64 NDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADH 123
ND L+ELF++++A K A A+R+ V+P F Y+RQD S+ I AKL+A+ + G +H
Sbjct: 61 NDRLIELFLLVDAAKKAVANRIILVMPYFGYARQDNIN-SQNIIPAKLIADFLEKLGVNH 119
Query: 124 VITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIAD 183
VITIDLH+ +I+ FFNIP+ NL EP I +I + + + V+V+PD G + R+ I++
Sbjct: 120 VITIDLHSDKIEKFFNIPISNL--EP-INLYIPF-LRTYSNFVIVAPDKGSINRVQKISN 175
Query: 184 RLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANK 243
L+ID A I+KER N + ++G V+ K I++DD+ D+ +TI+K A L+E A
Sbjct: 176 LLNIDSAYINKERDINNNCEMISIIGSVEGKNCILIDDIIDSGETIVKAARFLKEHSALS 235
Query: 244 IYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIR 301
+ AF+TH + A + +KI NS ++ I VT+TI + L PK I + ++ + +R
Sbjct: 236 VSAFITHAVLATGSKDKIENSVIDKIFVTDTI---EVGDLPPKFYIIPVMPIIVKELR 290
>UniRef50_Q6MW31 Cluster: Related to ribose-phosphate
pyrophosphokinase II; n=3; Sordariales|Rep: Related to
ribose-phosphate pyrophosphokinase II - Neurospora
crassa
Length = 501
Score = 192 bits (469), Expect = 8e-48
Identities = 101/231 (43%), Positives = 152/231 (65%), Gaps = 29/231 (12%)
Query: 111 LLANLISVAGADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSP 170
L+A+L++ AGAD ++T DLH S QGFF+IPVD+L A P + ++I+ +I +K +V+VSP
Sbjct: 266 LIADLLTCAGADRIVTCDLHESTYQGFFDIPVDHLIARPLLKRYIQHHIENYKEAVIVSP 325
Query: 171 DAGGVKRMTGIADRLDIDFAIIHKERQRANEG----DSTVLVGDVKNKTAIMVDDLADTC 226
DAGG KR IAD L + FA+IHKER+R ++ S +LVG+V N+ I+VDDLADT
Sbjct: 326 DAGGAKRAAAIADSLGLQFALIHKERRRPSKTHPNYPSMMLVGNVANRICILVDDLADTV 385
Query: 227 DTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMK---- 282
+TI + A+ L+ GA ++ A +THG+F+G+AI++IN S+L+ +VVTNT+ Q ++++
Sbjct: 386 NTITRAAKLLKREGAVQVVALITHGVFSGDAIQRINASALDRVVVTNTVAQHRHLEAFGA 445
Query: 283 ---------------------LCPKLQTIDISVMLAEAIRRTHYAESVSYL 312
+C KL+ +DI+ AEAIRR + ES+S L
Sbjct: 446 ARAGGTKEMPDKNKNDVDPRVVCGKLEVLDIAPFFAEAIRRIVFGESISML 496
Score = 54.4 bits (125), Expect = 4e-06
Identities = 31/79 (39%), Positives = 40/79 (50%), Gaps = 6/79 (7%)
Query: 19 IVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMINACK 78
I+ G+ R +N N S E ++ +ND +EL IMI+ACK
Sbjct: 56 IIQSFGVGTNRNAANSNNNNNNNDGSSTSATAETGHVT------VNDYFIELCIMISACK 109
Query: 79 IASASRVTAVVPCFPYSRQ 97
SA RVTAV+P FPYSRQ
Sbjct: 110 TGSARRVTAVLPFFPYSRQ 128
Score = 54.0 bits (124), Expect = 5e-06
Identities = 24/56 (42%), Positives = 36/56 (64%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQS 58
N+ V +G+SHP ++ LG+ +KFS+ ET EI +S+RG+DVYI+QS
Sbjct: 4 NVVVLSGNSHPKFVDSVCNYLGIPPASRVLEKFSSGETRCEIRDSIRGKDVYIIQS 59
>UniRef50_Q98R83 Cluster: Ribose-phosphate pyrophosphokinase; n=10;
Mycoplasma|Rep: Ribose-phosphate pyrophosphokinase -
Mycoplasma pulmonis
Length = 321
Score = 191 bits (466), Expect = 2e-47
Identities = 107/301 (35%), Positives = 178/301 (59%), Gaps = 5/301 (1%)
Query: 15 IAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMI 74
+A+ I L + L F++ E + E+VR +DV+IV S N+N+M+L I +
Sbjct: 17 LAQEICDELKMKLHSVNKTIFADGEVLLSSKETVRSKDVFIVASTSHPANNNIMDLLIFV 76
Query: 75 NACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQI 134
++ K ASA + ++ + Y+RQD+K + R PI AKLLA+L+ VAG ++ +DLH I
Sbjct: 77 DSLKRASAKTINVILSYYGYARQDRKAEGRQPIAAKLLADLLQVAGISRIVVVDLHNPSI 136
Query: 135 QGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRL--DIDFAII 192
QGFFNIPVD++ A+ ++K + I + K ++ VSPD GG R +A+ + D+ AII
Sbjct: 137 QGFFNIPVDDIKAQYILSK--EFTIKDEKFTI-VSPDHGGTIRARIMAEIISNDVKIAII 193
Query: 193 HKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGI 252
K R N+ + ++GD+ N+ A++VDD+ DT TI+ AE L++ GA KI +HGI
Sbjct: 194 DKRRVSTNKTEVLGVIGDINNENAVIVDDIIDTGGTIVNAAEVLKKNGAKKISIVASHGI 253
Query: 253 FAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRRTHYAESVSYL 312
F+ + ++ ++VTN+I + K KL+ + ++ L++ IR ++SVS +
Sbjct: 254 FSKGFDIFEDADVIDEVIVTNSIDNYELAKKYKKLKIVSLAPFLSKVIRSIMDSKSVSDI 313
Query: 313 F 313
+
Sbjct: 314 Y 314
>UniRef50_A7HHV4 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Cystobacterineae|Rep: Ribose-phosphate pyrophosphokinase
- Anaeromyxobacter sp. Fw109-5
Length = 311
Score = 187 bits (455), Expect = 4e-46
Identities = 105/298 (35%), Positives = 168/298 (56%), Gaps = 6/298 (2%)
Query: 6 VFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEIND 65
V +GS+HP++ + + RLGL ++F + E V + E VRG +VY+VQ +
Sbjct: 5 VLSGSAHPELTREVAERLGLTSAERVVERFPDGELRVVVKEPVRGAEVYLVQPLSPPADA 64
Query: 66 NLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVI 125
+L+EL + +AC+ A A VTAVVP ++RQD++ P A+L A+LIS A AD V+
Sbjct: 65 HLLELVFLADACRRAGARSVTAVVPYLAWARQDRRRVEGEPHGARLAADLIS-ARADRVV 123
Query: 126 TIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRL 185
++D+H +GFF++P+D+L A PA+ I ++P + +V+V PD G +R L
Sbjct: 124 SVDVHGPAAEGFFSVPLDHLTAAPALAAAIARSVP--RDAVVVGPDLGAARRAALFGRLL 181
Query: 186 DIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGAN-KI 244
+ AI+HK R A E + + G+V + I+VDD+ T TI L AG +I
Sbjct: 182 GLPSAIVHKARLSAREVEVRGVAGEVAGRAPILVDDMISTGATIEAAVRTLLAAGCRPEI 241
Query: 245 YAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRR 302
TH +F +A E++ + IVVT+ +P + L +L+ + ++ +LAEAI R
Sbjct: 242 VVAATHPLFTESAPERLARLPIARIVVTDALPVPRAPGL--ELEVVPLATLLAEAIAR 297
>UniRef50_Q9PQV0 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Ureaplasma parvum|Rep: Ribose-phosphate
pyrophosphokinase - Ureaplasma parvum (Ureaplasma
urealyticum biotype 1)
Length = 330
Score = 187 bits (455), Expect = 4e-46
Identities = 109/298 (36%), Positives = 164/298 (55%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGE 62
+I +F+ S+ +A I L + L KF++ E V VRG V I+QS
Sbjct: 6 DILLFSLSNSHQLANKIANLLKIELSPIRIDKFADGELIVAPQVPVRGRRVIIIQSTSKP 65
Query: 63 INDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGAD 122
+ND+LMEL I I++ K ASA ++ V+P + Y+RQD+K K R PITA+L+A +I AGA
Sbjct: 66 VNDSLMELLIAIDSIKRASAKAISVVIPYYGYARQDRKAKPREPITARLVAKMIESAGAT 125
Query: 123 HVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIA 182
V+T D+H+ Q QGFF+IP D+L A + K + + +VSPD GGVKR I+
Sbjct: 126 SVLTWDIHSLQTQGFFDIPFDSLEAVWVLMKHYFSAYKDSSNITIVSPDYGGVKRAREIS 185
Query: 183 DRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGAN 242
AI+ K R N+ + ++GDVK++ ++VDD+ DT TIL A+ +RE GA
Sbjct: 186 IATGATLAIVDKRRSGKNQVEINNVLGDVKDRDCVIVDDMIDTGGTILGAAKIVREKGAK 245
Query: 243 KIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAI 300
I THG+F NA + + + I+ I + L+ + I+ +A+ I
Sbjct: 246 SITIIATHGLFNNNARQHFQQAIKDRIINKICIADTIENEPFDGLEIVSIAPAIAKCI 303
>UniRef50_Q5GTH9 Cluster: Phosphoribosylpyrophosphate synthetase;
n=6; Wolbachia|Rep: Phosphoribosylpyrophosphate
synthetase - Wolbachia sp. subsp. Brugia malayi (strain
TRS)
Length = 308
Score = 186 bits (453), Expect = 7e-46
Identities = 106/310 (34%), Positives = 176/310 (56%), Gaps = 20/310 (6%)
Query: 4 IKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEI 63
+K+ G++ ++ K I +L + A KF++ N E+ ++ ++VYI+QS +
Sbjct: 1 MKIIIGNASKELGKLIANKLNVQPFSAQVSKFADGAINAEVESNLCSQEVYIIQSISPPV 60
Query: 64 NDNLMELFIMINACKIASASRVTAVVPCFPYSRQD---KKEKSRAPITAKLLANLISVAG 120
ND+LMEL +I+A K + R+T ++P + YSRQD K ++ + AKL+ANLI AG
Sbjct: 61 NDHLMELLFIIDAVKRSGTKRITTIIPYYGYSRQDRIIKNNNMQSALNAKLVANLIQTAG 120
Query: 121 ADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIK-ENIPEWKSSVMVSPDAGGVKRMT 179
A V IDLH+SQI+GFF++P+ NL A I EN+ +V+PD G + R
Sbjct: 121 ASSVAVIDLHSSQIEGFFDVPLTNLSCFEAFADSIHIENL------AIVAPDVGAIGRAR 174
Query: 180 GIADRLDIDFAI--------IHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILK 231
A L+ + I I K R++A ++G+ NK ++VDD+ D+ T+
Sbjct: 175 AFAKTLEKKYEIKLSDKIIIIDKYREKAGTSHVMNVIGEATNKNCVIVDDIVDSGGTLCN 234
Query: 232 GAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTID 291
A AL+ A + + +THG+ +GNAIEKI++SSL+ +V T+TI + ++ K++ +
Sbjct: 235 AALALKNRRARSVISCITHGVLSGNAIEKISSSSLDKLVTTDTIFHK--LEKTDKIEIVS 292
Query: 292 ISVMLAEAIR 301
I+ +L I+
Sbjct: 293 IANILTHFIQ 302
>UniRef50_Q16GA3 Cluster: Ribose-phosphate pyrophosphokinase 1,
putative; n=2; Aedes aegypti|Rep: Ribose-phosphate
pyrophosphokinase 1, putative - Aedes aegypti
(Yellowfever mosquito)
Length = 330
Score = 181 bits (441), Expect = 2e-44
Identities = 85/103 (82%), Positives = 94/103 (91%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGC 60
MPNIKVF+GSSHPD+A IV RLG++LG+ TKKFSN ET VEIGESVRGEDVYIVQSG
Sbjct: 37 MPNIKVFSGSSHPDLASRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGS 96
Query: 61 GEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKS 103
GEINDNLMEL IMINACKIASASRVTAV+PCFPY+RQDKK+K+
Sbjct: 97 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKA 139
>UniRef50_A3LVW1 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Saccharomycetales|Rep: Ribose-phosphate
pyrophosphokinase - Pichia stipitis (Yeast)
Length = 451
Score = 180 bits (438), Expect = 4e-44
Identities = 101/265 (38%), Positives = 152/265 (57%), Gaps = 30/265 (11%)
Query: 79 IASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFF 138
I + S T + P Y + + K L+ANL+ AGAD +IT+DLH Q QGFF
Sbjct: 183 IVTNSASTNLPPVDAYGKTESGYKQWIAQNGTLIANLLVTAGADRLITMDLHDPQFQGFF 242
Query: 139 NIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQR 198
NIPVDNLY+ P + +I + IP ++ V+VSPD+GG KR T +AD + FA+IHKER+
Sbjct: 243 NIPVDNLYSRPLLKHYILDYIPNYQECVIVSPDSGGAKRATAVADAIGCSFALIHKERRA 302
Query: 199 ----------------ANEGDSTVL-VGDVKNKTAIMVDDL-----------ADTCDTIL 230
+T+L + T ++V D+ DT TI
Sbjct: 303 KVAKNPPSTAASSSSVPMSASNTILSSSNTMVATTMLVGDVRDKVCVLIDDLVDTSYTIT 362
Query: 231 KGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKL--CPKLQ 288
+ A+ L++ GA +YA +THG+F+G+AI ++N S+++ ++ TN++PQ + MK+ K +
Sbjct: 363 RAAKLLKDQGAKYVYALVTHGVFSGDAINRVNKSAIDKVITTNSVPQSERMKVLGSDKFE 422
Query: 289 TIDISVMLAEAIRRTHYAESVSYLF 313
+D+S +LAE+IRR H ESVS LF
Sbjct: 423 VLDVSRILAESIRRIHNGESVSMLF 447
Score = 123 bits (297), Expect = 5e-27
Identities = 57/97 (58%), Positives = 74/97 (76%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGC 60
M ++ V GSSHP + +TI L + G +++KFSN ET++EI +SVR +DV+IVQSGC
Sbjct: 1 MRDLVVLGGSSHPSLTRTICRNLTIEQGEVSSRKFSNGETSLEIQDSVREKDVFIVQSGC 60
Query: 61 GEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQ 97
G++NDN +EL IMI ACK ASA RVTAV+P FPYSRQ
Sbjct: 61 GDVNDNFIELLIMIAACKTASAKRVTAVLPLFPYSRQ 97
>UniRef50_O60256 Cluster: Phosphoribosyl pyrophosphate
synthetase-associated protein 2; n=62; Eumetazoa|Rep:
Phosphoribosyl pyrophosphate synthetase-associated
protein 2 - Homo sapiens (Human)
Length = 369
Score = 180 bits (438), Expect = 4e-44
Identities = 86/192 (44%), Positives = 129/192 (67%), Gaps = 1/192 (0%)
Query: 8 TGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNL 67
+ SS +++K I RLG+ +G+ + N+ET V+I ESVRG+DV+I+Q+ ++N +
Sbjct: 27 SNSSCMELSKKIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTI 86
Query: 68 MELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITI 127
MEL IM+ ACK + A + V+P FPYS+Q K K R I +KLLA+++ AG H+IT+
Sbjct: 87 MELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMRK-RGSIVSKLLASMMCKAGLTHLITM 145
Query: 128 DLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDI 187
DLH +IQGFFNIPVDNL A P + ++I+E IP+++++V+V+ KR A+RL +
Sbjct: 146 DLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDYRNAVIVAKSPASAKRAQSFAERLRL 205
Query: 188 DFAIIHKERQRA 199
A+IH E Q A
Sbjct: 206 GIAVIHGEAQDA 217
Score = 121 bits (292), Expect = 2e-26
Identities = 55/110 (50%), Positives = 78/110 (70%)
Query: 207 LVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSL 266
+VGDV + AI+VDD+ D D+ L AE L+E GA KI+ THG+ + +A +I S++
Sbjct: 256 VVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFVMATHGLLSSDAPRRIEESAI 315
Query: 267 EAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRRTHYAESVSYLFTNV 316
+ +VVTNTIP E CPK++T+DIS++L+EAIRR H ES+SYLF N+
Sbjct: 316 DEVVVTNTIPHEVQKLQCPKIKTVDISMILSEAIRRIHNGESMSYLFRNI 365
>UniRef50_Q2S5C7 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Salinibacter ruber DSM 13855|Rep: Ribose-phosphate
pyrophosphokinase - Salinibacter ruber (strain DSM
13855)
Length = 325
Score = 176 bits (428), Expect = 7e-43
Identities = 107/323 (33%), Positives = 168/323 (52%), Gaps = 12/323 (3%)
Query: 1 MPN-IKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSG 59
MP+ +++F S + I + L L + F++ E V +VRG DV++VQS
Sbjct: 1 MPDDLRLFALSESRGFGEAIASALDTELDAHHERTFTDGEHEVRPEVNVRGRDVFVVQSL 60
Query: 60 CGE----INDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANL 115
+ +ND L L M+ A + ASA RVTAV+P Y R+D+K + R P+T + +A L
Sbjct: 61 YADDTWSVNDKLCRLLFMLGALRDASAERVTAVIPYLCYQRKDRKTRPRGPVTTRYVAGL 120
Query: 116 ISVAGADHVITIDLH-ASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGG 174
G D V+T+D+H + +Q F ++L P + + + + +V VSPD GG
Sbjct: 121 FEAVGVDRVLTMDVHNLAVLQNAFQARTEHLLGHPLFVHRLTDVVGAEEVAV-VSPDEGG 179
Query: 175 VKRM----TGIADRLDIDFAIIHKERQRANEG-DSTVLVGDVKNKTAIMVDDLADTCDTI 229
VKR G+ L+ + E+ R ++G LVG V+++TAI+VDD+ T T+
Sbjct: 180 VKRAGKFAEGLGAVLNCEVPTAFVEKMRKDDGVTGGALVGSVEDRTAIVVDDMVSTAGTM 239
Query: 230 LKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQT 289
+ + E GA +YA THG+F G A E++ + L+A+ VTNT+ +LQ
Sbjct: 240 TQAIRSCAEEGAESVYAVATHGLFVGEADERLETAPLDALFVTNTVAPRLTGAAAERLQI 299
Query: 290 IDISVMLAEAIRRTHYAESVSYL 312
+ + A AI+ H SVS L
Sbjct: 300 CNAAPRFAAAIQAVHTETSVSAL 322
>UniRef50_Q0U4M1 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Phaeosphaeria nodorum|Rep: Ribose-phosphate
pyrophosphokinase - Phaeosphaeria nodorum (Septoria
nodorum)
Length = 464
Score = 172 bits (419), Expect = 9e-42
Identities = 76/132 (57%), Positives = 103/132 (78%)
Query: 68 MELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITI 127
MEL IMI+ACK SA +TAV+P FPYSRQ KK++ R ITA+++ANL+ VAG +HVIT+
Sbjct: 1 MELLIMISACKGGSAKSITAVMPYFPYSRQSKKKQHRGAITARMVANLLHVAGVNHVITL 60
Query: 128 DLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDI 187
DLHASQ+QGFF PVDNL AEP +++WI+ N+P W+ +V+VS + GG KR+T +AD L +
Sbjct: 61 DLHASQMQGFFKCPVDNLVAEPLLSRWIRVNVPNWREAVVVSKNPGGTKRVTSLADALKL 120
Query: 188 DFAIIHKERQRA 199
F I+ +R+RA
Sbjct: 121 SFGIVTTDRRRA 132
Score = 91.5 bits (217), Expect = 3e-17
Identities = 47/111 (42%), Positives = 71/111 (63%), Gaps = 4/111 (3%)
Query: 207 LVGDVKNKTAIMVDDLADTCDTILKGAEAL-REAGANKIYAFLTHGIFAGNAIEKINNSS 265
LVG+VKN+ +VDD+ D + + AE + + GA K+Y F THG+F G+ +E++N
Sbjct: 350 LVGNVKNRPVFIVDDMMDKSASWIAAAETVVKRGGATKVYCFATHGLFGGDCLEEMNKCD 409
Query: 266 L-EAIVVTNT--IPQEKNMKLCPKLQTIDISVMLAEAIRRTHYAESVSYLF 313
L E I++TN IP+ K + KL I++ +LAE+IRR H+ ES+S LF
Sbjct: 410 LIEKIIITNAFPIPEYKQDQARNKLVVINVDNLLAESIRRNHHGESMSQLF 460
>UniRef50_A5DKD0 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
Saccharomycetaceae|Rep: Ribose-phosphate
pyrophosphokinase - Pichia guilliermondii (Yeast)
(Candida guilliermondii)
Length = 472
Score = 167 bits (405), Expect = 4e-40
Identities = 102/237 (43%), Positives = 142/237 (59%), Gaps = 34/237 (14%)
Query: 111 LLANLISVAGADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSP 170
L+ANL+ AGAD +T+DLH Q QGFFNIPVDNLY++P + +I + IP ++ V+VSP
Sbjct: 232 LIANLLMTAGADRCVTMDLHDPQFQGFFNIPVDNLYSKPLLKHYIIDYIPNYQQCVIVSP 291
Query: 171 DAGGVKRMTGIADRLDIDFAIIHKERQ-RANEGDSTVLVG--------------DVKN-- 213
D+GG KR T IAD + FA+IHKER+ +AN G V N
Sbjct: 292 DSGGAKRATSIADAIGCQFALIHKERRAKANSSGPPSAPGPLGTRSAGGFSSTSSVNNPN 351
Query: 214 -----KTAIMVDDLAD-TC-------DT---ILKGAEALREAGANKIYAFLTHGIFAGNA 257
T ++V D+ D C DT I + A+ L++ GA +YA +THG+F+G+A
Sbjct: 352 GHQLVATTMLVGDVRDRVCVLVDDLVDTSYTITRAAKLLKDQGALYVYALVTHGVFSGDA 411
Query: 258 IEKINNSSLEAIVVTNTIPQEKNMK-LCPKLQTIDISVMLAEAIRRTHYAESVSYLF 313
I +I SS++ ++ TN+ PQ+ + + L KL ID+S +LAEAIRR H ESVS LF
Sbjct: 412 INRIAKSSIDKLITTNSTPQKTHSEMLGDKLVVIDVSRVLAEAIRRIHNGESVSMLF 468
Score = 109 bits (262), Expect = 9e-23
Identities = 54/97 (55%), Positives = 67/97 (69%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGC 60
M N+ V G+SHPD+ K+I L +FSN ET++EI SVR +DV+I+QSG
Sbjct: 1 MRNLVVLGGTSHPDLTKSICRILTTEESDVNIGRFSNGETSIEIQGSVRDKDVFIIQSGS 60
Query: 61 GEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQ 97
G INDN ++L IMI ACK ASA RVTAV+P FPYSRQ
Sbjct: 61 GHINDNFVQLLIMIAACKTASARRVTAVLPLFPYSRQ 97
>UniRef50_Q3YQZ8 Cluster: Ribose-phosphate pyrophospho kinase; n=1;
Ehrlichia canis str. Jake|Rep: Ribose-phosphate
pyrophospho kinase - Ehrlichia canis (strain Jake)
Length = 318
Score = 165 bits (402), Expect = 1e-39
Identities = 102/314 (32%), Positives = 175/314 (55%), Gaps = 22/314 (7%)
Query: 6 VFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESV--RGEDVYIVQSGCGEI 63
+ +G+S ++A+ I G+ L +FS++E NVE+ E+ + + V ++ S C
Sbjct: 3 ISSGTSSINLARCISKTTGIKLINTCITRFSDQELNVEVQENQDDKNKHVIVINSLCFPA 62
Query: 64 NDNLMELFIMINACKIASA-SRVTAVVPCFPYSRQDKK-----EKSR---APITAKLLAN 114
+DNL+EL ++I+A A S++T +VP Y+RQD+ + S + ++AK++ N
Sbjct: 63 HDNLIELLLLIDATNRALCPSKITLIVPYLCYTRQDRVMYRNLDSSSLMVSALSAKVIIN 122
Query: 115 LISVAGADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGG 174
+ A +++I IDLH++Q+ GFF+ + NL + + I + + V+VSPD G
Sbjct: 123 TLETANINNIIFIDLHSNQLTGFFDTSITNLSSHAIFIEDIAGKY-DMDNLVIVSPDYGA 181
Query: 175 VKRMTGIADRL--------DIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTC 226
+ R A+ L +I A+I K R + + + G+V+NK I++DD+ D+
Sbjct: 182 LNRTRVFANALSRQYKLNNEIQVAVIDKYRAKPGVSEVMNIAGNVENKDCIIIDDIVDSA 241
Query: 227 DTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPK 286
T+ A AL++ GA K+ A++THGI +GNAIEK+ NS L+ + TNTI + PK
Sbjct: 242 GTLCNAASALKDKGALKVSAYVTHGILSGNAIEKVTNSKLDNLTTTNTI--NHSSFNTPK 299
Query: 287 LQTIDISVMLAEAI 300
+Q + I L+ I
Sbjct: 300 IQILSIDKFLSNYI 313
>UniRef50_UPI00006CD8E2 Cluster: ribose-phosphate pyrophosphokinase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
ribose-phosphate pyrophosphokinase family protein -
Tetrahymena thermophila SB210
Length = 447
Score = 165 bits (401), Expect = 1e-39
Identities = 102/310 (32%), Positives = 169/310 (54%), Gaps = 8/310 (2%)
Query: 6 VFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCG-EIN 64
VFTGS + ++AK +V++L + L R + K ET +EI +SVRG+ V+++QS C IN
Sbjct: 101 VFTGSGNRELAKEVVSQLDIQLSRISIHKNPESETEIEILDSVRGKRVFVIQSLCQPSIN 160
Query: 65 DNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKE--KSRAPITAKLLANLISVAGAD 122
DN+MEL++M +A K + A++VT +VP F YSRQ E K R + + ++ G D
Sbjct: 161 DNIMELYLMCSALKRSGAAKVTCIVPYFAYSRQTSAESDKERRSLNGSDICLMLQTMGCD 220
Query: 123 HVITIDLHASQIQGFF--NIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTG 180
VITI+ +++GFF +P+ N+ + ++ E E + + VKR+ G
Sbjct: 221 QVITINYGQIEVKGFFAPRVPILNIDVNEMVVPYLLEKGIENPVLIGAHLRSRNVKRLIG 280
Query: 181 IADRLDI-DFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREA 239
+ ++ D R N + DVKN+ I+ ++L D+ +++ + + L +
Sbjct: 281 LHKIFNLFDQNPSLGFMIRGNAEKIEYIGEDVKNRDCILFENLIDSGNSLQELSLKLHKD 340
Query: 240 GANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEA 299
GA +I+ F HG+F NA + I NS +E +VTNT + K PK+Q + ++ +LAE
Sbjct: 341 GARRIFWFSPHGLFTDNAQKLIKNSFVEECIVTNTCEEVKPQH--PKIQYLSVAKLLAEV 398
Query: 300 IRRTHYAESV 309
I H S+
Sbjct: 399 ISFLHSGHSL 408
>UniRef50_A4BQ39 Cluster: Ribose-phosphate pyrophosphokinase; n=9;
Proteobacteria|Rep: Ribose-phosphate pyrophosphokinase -
Nitrococcus mobilis Nb-231
Length = 362
Score = 161 bits (391), Expect = 2e-38
Identities = 102/311 (32%), Positives = 163/311 (52%), Gaps = 13/311 (4%)
Query: 14 DIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIV----QSGCGEINDNLME 69
+ + + A LG L + F + E E VRG DVY++ Q +ND L+
Sbjct: 46 EYGQQVAACLGGELATHEERAFEDGEHKSRPLEGVRGRDVYVLHSLYQDASEGVNDKLVR 105
Query: 70 LFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDL 129
L + A + A A +TAV+P Y+R+D++ K R P+T + +A L+ G D V+T+D+
Sbjct: 106 LLFFLGALRDAHAGCLTAVIPYLAYARKDRRTKPRDPVTTRYVAQLLEAVGVDRVLTMDV 165
Query: 130 H-ASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRL--- 185
H + + F +PV +L A + + + V+VSPDAGG KR + + L
Sbjct: 166 HNIAAFENAFRVPVVHLEAGALFVRALCRQAGD-SEVVVVSPDAGGYKRAERLRELLAKQ 224
Query: 186 -DIDFAIIHKERQRANEGDS-TVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANK 243
+ E++R+++ S LVG+V + A++VDDL T T++K A A R+AGA
Sbjct: 225 RSSSPGLAFMEKKRSDDVVSGEALVGEVSGRVAVIVDDLISTGGTLVKAAMACRKAGARA 284
Query: 244 IYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMK--LCPKLQTIDISVMLAEAIR 301
+YA THG+F G A + + LE + VT+T+P + L ++ + + +L EAIR
Sbjct: 285 VYAAATHGLFTGAASRVLAGAPLERLFVTDTVPPFRLQAEVLQNRVTLVPTAPLLGEAIR 344
Query: 302 RTHYAESVSYL 312
R H S+S L
Sbjct: 345 RLHTDGSLSEL 355
>UniRef50_Q2GIZ1 Cluster: Ribose-phosphate pyrophosphokinase; n=6;
Anaplasmataceae|Rep: Ribose-phosphate pyrophosphokinase
- Anaplasma phagocytophilum (strain HZ)
Length = 322
Score = 158 bits (384), Expect = 2e-37
Identities = 91/311 (29%), Positives = 173/311 (55%), Gaps = 20/311 (6%)
Query: 6 VFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEI--GESVRGEDVYIVQSGCGEI 63
+ GS+ +AK++ L + + +F++ E N+E+ G + + ++QS
Sbjct: 3 IIPGSTSLALAKSVSGMLDVPMVIPCVSRFADGEINLEVPTGVATGSGHIVLMQSLSAPA 62
Query: 64 NDNLMELFIMINACKIASA-SRVTAVVPCFPYSRQDK-------KEKSRAPITAKLLANL 115
+DNL+EL ++ +A + A R+TAV+P YSRQD+ +E + ++AK++A +
Sbjct: 63 SDNLIELTLLTDAVRRTLAPQRITAVIPYLCYSRQDRVMQRVDSQETFTSALSAKVIARI 122
Query: 116 ISVAGADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKE-NIPEWKSSVMVSPDAGG 174
+S +G DH++T+DLH+ Q GFF++P N+ A ++ N+ E V+VSPD G
Sbjct: 123 LSTSGLDHIVTLDLHSQQAAGFFDVPFTNISAYDVFVDYLSSSNLLE--RLVIVSPDYGA 180
Query: 175 VKRMTGIADRLD-------IDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCD 227
+ R+ L I A+I K R+ + +VG+V+++ ++DD+ D+
Sbjct: 181 LGRVRAFVRMLSSRYNMNSIQVAVIDKYREGPGISEVMHVVGNVQDRHCFILDDIVDSGG 240
Query: 228 TILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKL 287
T+ A AL+ GA +++F+THG+ +G AI+ I + L+++V+T+TI + L K+
Sbjct: 241 TLCNAAAALKTRGAISVHSFITHGVLSGRAIDAIGTAELDSLVITDTIHNPDRVNLPEKI 300
Query: 288 QTIDISVMLAE 298
+ + + +L++
Sbjct: 301 KVLSVDRLLSD 311
>UniRef50_Q2GCV8 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Neorickettsia sennetsu str. Miyayama|Rep:
Ribose-phosphate pyrophosphokinase - Neorickettsia
sennetsu (strain Miyayama)
Length = 305
Score = 153 bits (370), Expect = 8e-36
Identities = 94/305 (30%), Positives = 163/305 (53%), Gaps = 14/305 (4%)
Query: 4 IKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGES--VRGEDVYIVQSGCG 61
+KV GS + + I + L L + RA +F + E++V + + G V ++QS C
Sbjct: 1 MKVLMGSKAGKLGQEIASLLNLAVVRAQANRFPDGESDVLVHHEDVIPGTKVLVIQSLCS 60
Query: 62 EINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGA 121
+ + +ME +++A + V P F Y+R D+ + I+AK++A LI
Sbjct: 61 DAD--IMEFLFIVDALNRLGVRDIALVSPYFGYARADRIVAPGSAISAKVVARLIGER-I 117
Query: 122 DHVITIDLHASQIQGFFNIPVDNLYAEPAITKW--IKENIPEWKSSVMVSPDAGGVKRMT 179
+ +D+H Q +GFF IPV N I W +KE++ + +V+PD G VK++
Sbjct: 118 SLLFVLDVHFPQFEGFFEIPVYN------ILPWTLLKESVHVGHNMALVAPDVGAVKKLK 171
Query: 180 GIADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREA 239
+++ L + I++K R RA + T +VG++ + I+VDD+ T+ A L+E
Sbjct: 172 PLSEELGTNLVIMNKRRPRACLSEVTEVVGEIHGRDCIIVDDIVCGGGTLCNSAAKLKEL 231
Query: 240 GANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEA 299
GA + AF+THG+F+G+A +KI +S ++ IVVTN+IP + K++ I + +LA
Sbjct: 232 GAKSVAAFVTHGVFSGSARQKIMDSQIDRIVVTNSIP-GPGCEAKGKIEIISAADLLARK 290
Query: 300 IRRTH 304
I +
Sbjct: 291 IHSVY 295
>UniRef50_A2AAG9 Cluster: Likely ortholog of H. sapiens
phosphoribosyl pyrophosphate synthetase- associated
protein 1; n=21; Coelomata|Rep: Likely ortholog of H.
sapiens phosphoribosyl pyrophosphate synthetase-
associated protein 1 - Mus musculus (Mouse)
Length = 175
Score = 150 bits (363), Expect = 5e-35
Identities = 74/153 (48%), Positives = 106/153 (69%), Gaps = 3/153 (1%)
Query: 22 RLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMINACKIAS 81
RLG LG++ + +N ET VEI ESVRG+D++I+Q+ ++N +MEL IM A K A
Sbjct: 22 RLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTAC 81
Query: 82 ASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFFNIP 141
A + V+P FPYS+Q K K R I KLLA++++ AG H+IT+DLH +IQGFF+ P
Sbjct: 82 ARNIIGVIPYFPYSKQSKMRK-RGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFP 140
Query: 142 VDNLYAEPAITKWIKENIPEWKSSVMV--SPDA 172
VDNL A P + ++I+E IP ++++V+V SPDA
Sbjct: 141 VDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDA 173
>UniRef50_Q8KKS6 Cluster: Ribose-phosphate pyrophosphokinase
protein; n=1; Rhizobium etli CFN 42|Rep:
Ribose-phosphate pyrophosphokinase protein - Rhizobium
etli (strain CFN 42 / ATCC 51251)
Length = 313
Score = 145 bits (352), Expect = 1e-33
Identities = 85/271 (31%), Positives = 140/271 (51%), Gaps = 5/271 (1%)
Query: 32 TKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMINACKIASASRVTAVVPC 91
T+ FSN + V + G +V +VQ+ ++D L ELF+ + A + +TAV+P
Sbjct: 45 TQVFSNGQMAVTPRDGGLGGNVVVVQTFPDSVHDRLFELFLALGAVRARGPRTITAVLPY 104
Query: 92 FPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFFNIPVDNLYAEPAI 151
PYSR D+ P+ ++LA +I G D +IT +LH Q+ F PV NL PA+
Sbjct: 105 LPYSRSDRPAFDGGPVPVRILAGIIETLGIDRLITFELHVPQLCAAFACPVVNLQFAPAL 164
Query: 152 TKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANE-GDSTVLVGD 210
+ + + ++VSPD GG KR +A L FA++ K R+ ++ +S ++GD
Sbjct: 165 VRHLGSAAVD--GDMVVSPDFGGAKRAEHLAALLGCPFAVMRKHRRDDDDFRESVEILGD 222
Query: 211 VKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIV 270
V +T I++DD ++ T A L+ AGA KI H IF + E S ++ IV
Sbjct: 223 VAGRTIILIDDEINSGQTAFSAAAHLKAAGARKITLAAAHAIFTPSLNENWGRSQIDRIV 282
Query: 271 VTNTIPQEKNMKLCPKLQTIDISVMLAEAIR 301
VT+++ + N ++ + I +A A++
Sbjct: 283 VTDSVGRTDNFP--DSVEVVSIGNEIAGALQ 311
>UniRef50_O26877 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Methanobacteriaceae|Rep: Ribose-phosphate
pyrophosphokinase - Methanobacterium thermoautotrophicum
Length = 285
Score = 143 bits (347), Expect = 5e-33
Identities = 86/269 (31%), Positives = 143/269 (53%), Gaps = 5/269 (1%)
Query: 10 SSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLME 69
S+ +A ++ L L T+KF + E + + E V GE V +VQS ++NLME
Sbjct: 6 SASQKLAASVADLLDEPLCPVETRKFPDGERYIRVKEEVEGE-VTVVQSTGYPQDENLME 64
Query: 70 LFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDL 129
L MI K A V A +P F Y RQ+++ KS ++AK++A+L+ AGAD ++T++L
Sbjct: 65 LLFMIENLKDLGADYVRAAIPYFGYGRQERRFKSGEAVSAKIVAHLLEAAGADEIVTVNL 124
Query: 130 HASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDF 189
H + + FF +PV L A P I E+I V+++PD G + ++D L +
Sbjct: 125 HENCLSEFFRVPVRELSAMPLIA----EHISFLDDPVIIAPDKGALGHAREVSDILGCEC 180
Query: 190 AIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLT 249
+ K R ++ V DV+ K A++VDD+ T TI+ A L + GA+ I
Sbjct: 181 DYMEKVRISPEVVETRVSDLDVEGKDAVVVDDIISTGGTIVNAAGILGKCGASSITVCCV 240
Query: 250 HGIFAGNAIEKINNSSLEAIVVTNTIPQE 278
H + +A+ KI ++ +E ++ T+T+ +
Sbjct: 241 HPVLVEDALLKIFSAGVERVIATDTLKSD 269
>UniRef50_Q4XQD5 Cluster: Ribose-phosphate pyrophosphokinase,
putative; n=1; Plasmodium chabaudi|Rep: Ribose-phosphate
pyrophosphokinase, putative - Plasmodium chabaudi
Length = 465
Score = 138 bits (333), Expect = 2e-31
Identities = 102/352 (28%), Positives = 185/352 (52%), Gaps = 50/352 (14%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQS---G 59
N+++F+ +SH ++A I + LG++LGRA K+S+ E ++I + VRG DVYI+ S G
Sbjct: 102 NMQIFSSNSHHELANEICSNLGISLGRAYIGKYSDGEITLQIMDEVRGRDVYIIHSTPAG 161
Query: 60 CGEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKE---KSRAPITAKLLANLI 116
+++ LMELF+ ++ + +SA +V V+P YSRQ+K+ + + A +A L+
Sbjct: 162 GKDVHSRLMELFLFVSTLRRSSAKKVIVVLPYLNYSRQNKQTGYFNNMHSLGAPEIAILL 221
Query: 117 SVAGADHVITIDLHASQIQGF------FNIPVDNLYAEPAITKWIKENIPEWKSSVMVSP 170
GAD +I +DL+ +I+GF F P+ N+ + +++K+ + + V+V
Sbjct: 222 QTCGADSIIAVDLNNPRIEGFSTDQKLFQPPLMNINPQSLAVEYLKKK--KLHNPVIVPI 279
Query: 171 DAGGVKRMTGIADRL-----DIDFAII---------HKERQRANEG-DSTVLVGDVKNKT 215
+ G ++ R+ D+ F + + +NE DS+ ++ + +N T
Sbjct: 280 NIDGAEKAKEFWVRMKKHSNDVGFTTLVSSTYDGTSTRGEAPSNESKDSSKMLTNKQNNT 339
Query: 216 -------AIMVDDLADTCDTIL------------KGAEALREAGANKIYAFLTHGIFAGN 256
+V D+ D CD I+ K A L+ AGA KIY + TH I +
Sbjct: 340 NSLENEKITIVGDIKD-CDCIIVNDILDTGEKSKKVAALLKNAGARKIYLYATHAILSDG 398
Query: 257 AIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRRTHYAES 308
+ KIN+S ++ +V TNTI +++ C K+ + ++ ++AE I+R + +S
Sbjct: 399 CVSKINDSCIDEVVTTNTIHIPRDV-CCEKMHILSVAKLVAEGIKRFNNEQS 449
>UniRef50_O59586 Cluster: Ribose-phosphate pyrophosphokinase; n=4;
Thermococcaceae|Rep: Ribose-phosphate pyrophosphokinase
- Pyrococcus horikoshii
Length = 287
Score = 136 bits (329), Expect = 7e-31
Identities = 77/256 (30%), Positives = 144/256 (56%), Gaps = 8/256 (3%)
Query: 33 KKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMINACKIASASRVTAVVPCF 92
KKF + E V I E GE+V +VQS +++L+E I+ +A K A ++ VVP
Sbjct: 30 KKFPDGEKYVRILE--HGEEVIVVQSTYRPQDEHLIETIIIGDALKEAGFEKLKLVVPYL 87
Query: 93 PYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFFNIPVDNLYAEPAIT 152
YSRQD+ K PI+ + + ++ + D + D+H + FF N+Y I
Sbjct: 88 AYSRQDRVTKEGEPISVRAIMKMLGLY-YDELYVFDIHNPKTLDFFPGKAVNIYPAKVIA 146
Query: 153 KWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVGDVK 212
++ ++ + ++ ++++PD G ++R +A+ L ++++ KER E T + +VK
Sbjct: 147 EYFRDKL---ENGLVLAPDRGALERAKEVANILGLEYSHFEKERISPTEVKMTPVDVNVK 203
Query: 213 NKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVT 272
+ ++VDD+ T T+++ AE L++ GA K++ THG+FA AIE++ + +++ + VT
Sbjct: 204 GRNVLIVDDIISTGGTMIRAAEILKDLGAEKVFVVATHGVFAEGAIERV-SKAVDELAVT 262
Query: 273 NTIPQE-KNMKLCPKL 287
NTIP + + + P++
Sbjct: 263 NTIPTKVSKISIVPEI 278
>UniRef50_Q8TUT6 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Methanopyrus kandleri|Rep: Ribose-phosphate
pyrophosphokinase - Methanopyrus kandleri
Length = 291
Score = 136 bits (329), Expect = 7e-31
Identities = 78/271 (28%), Positives = 140/271 (51%), Gaps = 3/271 (1%)
Query: 6 VFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEIND 65
V S + + + L L +F + E V + + G V +V S ++
Sbjct: 3 VLATSEGVKLGRRLAEELDAELAPVEEDRFPDGEQIVRVPPELDGT-VVVVHSMSPPQDE 61
Query: 66 NLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVI 125
NL++ I ++A + A V A+VP YSRQD++ + P++ + +A +S A AD +I
Sbjct: 62 NLVKAIITLDAARENGAEEVIAIVPYMAYSRQDRRFEPGEPVSFRAVARAVS-ANADALI 120
Query: 126 TIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRL 185
T+DLH +F++P +N+ A + K++ E E + V++ PD G + +A
Sbjct: 121 TVDLHEPGTLKYFDVPAENVSAAEELGKYLAERF-EGEDLVVIGPDEGARELAREVASIC 179
Query: 186 DIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIY 245
+++ + K+R +E + DV+ +T ++VDD+ DT T+++ A ALR+ GA +Y
Sbjct: 180 GVEYDHLEKKRLSGDEVEIHPKELDVEGRTVVLVDDMIDTGGTMVEAARALRDQGAGTLY 239
Query: 246 AFLTHGIFAGNAIEKINNSSLEAIVVTNTIP 276
A TH + NA ++ S E I+ T+T+P
Sbjct: 240 AACTHALLTRNAATRLLASGFEDIIATDTVP 270
>UniRef50_UPI00015BACA3 Cluster: ribose-phosphate pyrophosphokinase;
n=1; Ignicoccus hospitalis KIN4/I|Rep: ribose-phosphate
pyrophosphokinase - Ignicoccus hospitalis KIN4/I
Length = 298
Score = 136 bits (328), Expect = 9e-31
Identities = 74/262 (28%), Positives = 135/262 (51%), Gaps = 6/262 (2%)
Query: 19 IVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMINACK 78
+VA L KKF + E+ V I V GEDV +V +G + ND ++E+ + I+ K
Sbjct: 17 LVASLNAEAHFIERKKFPDGESYVRIPIPVSGEDVLVVHTGFPDQNDRVIEVLLTIDTLK 76
Query: 79 IASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFF 138
A VT ++P PY+RQD++ + P++ K L +S D+++ +D+H F
Sbjct: 77 DLGAESVTLLMPYMPYARQDRRFREGEPVSIKTLLKTLSNLDLDYLVVVDIHKEYSLSEF 136
Query: 139 NIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQR 198
N+ P + + IK+ + + ++++PD G R +A L + + K R R
Sbjct: 137 GGGAFNVSVLPYLAEKIKDEV---EDPLVLAPDRGATARAKSVASVLKAPWDYLEKRRDR 193
Query: 199 ANEGDSTVLVGDV--KNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGN 256
G+ T+ ++ + KT I+VDD+ T T+ A+ L+ AGA ++ A + H + G+
Sbjct: 194 VT-GEVTIRPKEISAEGKTVIIVDDMVSTGSTLALAAKQLKAAGAKRVLALVAHALMVGD 252
Query: 257 AIEKINNSSLEAIVVTNTIPQE 278
A K+ + +E ++ NT+ ++
Sbjct: 253 AENKLREAGVERVITANTLARD 274
>UniRef50_A3DNX0 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Staphylothermus marinus F1|Rep: Ribose-phosphate
pyrophosphokinase - Staphylothermus marinus (strain ATCC
43588 / DSM 3639 / F1)
Length = 304
Score = 135 bits (326), Expect = 2e-30
Identities = 81/303 (26%), Positives = 152/303 (50%), Gaps = 11/303 (3%)
Query: 6 VFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIG--ESVRGEDVYIVQSGCGEI 63
V G ++ A+ + LG L TK F + E V I E + G V I+ +
Sbjct: 7 VIAGKNYETFAEKYASLLGYELVDIQTKIFPDGEYYVRIKKPELISGNKVVIINTMYPRQ 66
Query: 64 NDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADH 123
ND+L+E ++I+A + + A + ++P Y+RQDK P+TA ++ +I GA+
Sbjct: 67 NDSLLETLMLIDAARRSGAKDIVVIIPYLAYARQDKVFLEGEPVTASIVVKMIRTIGANA 126
Query: 124 VITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIAD 183
++ +D+H+ + FN N+ + +++ + ++++PD G + R A+
Sbjct: 127 LVVVDIHSVKTLEDFNGKTLNILVSDEL---VEKALSILNDPIVIAPDKGALHRARYAAE 183
Query: 184 RLDIDFAIIHKERQRANEGDSTVLVGDVK--NKTAIMVDDLADTCDTILKGAEALREAGA 241
R +++ + K+R R G+ +++ +++ + +++DD+ T TI LR GA
Sbjct: 184 RHGLEYDYLIKKRDRIT-GEISMMPKELRIDGRDIVIIDDIISTGGTIANATRILRSHGA 242
Query: 242 NKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIR 301
KI THG+F GNA EKI ++ +E I V NT+ P ++T+D+S + +R
Sbjct: 243 RKIVVAATHGLFIGNAFEKIRSAGVEKIYVANTLGITHKE---PLIETVDVSEKVVTEMR 299
Query: 302 RTH 304
+
Sbjct: 300 NNN 302
>UniRef50_Q88JA5 Cluster: Ribose-phosphate pyrophosphokinase family
protein; n=3; Pseudomonas|Rep: Ribose-phosphate
pyrophosphokinase family protein - Pseudomonas putida
(strain KT2440)
Length = 319
Score = 132 bits (320), Expect = 9e-30
Identities = 92/307 (29%), Positives = 148/307 (48%), Gaps = 15/307 (4%)
Query: 6 VFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEIN- 64
+F D + RLG L + + + E GESV G V + S G+ +
Sbjct: 8 LFALQGSQDYGNAVAQRLGRKLSAHEERDYEDGEHKCWPGESVDGRSVIVFHSLYGDAHH 67
Query: 65 ---DNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGA 121
D L L A K A+A +VTAV P Y R+D+K + + I + +A L+ G
Sbjct: 68 SAHDKLCRLLFFCGALKDAAARQVTAVTPYLCYGRKDRKVEFQDAIITRHVARLMESCGV 127
Query: 122 DHVITIDLH-ASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTG 180
D ++ +D+H S + IP NL + + + E ++ +VSPD GGVKR
Sbjct: 128 DRIVALDVHNPSAFDNAYRIPSWNLQCTQLFAQRLAPLLGE-QAVTVVSPDIGGVKRAEQ 186
Query: 181 IADRL------DIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAE 234
L + A++ K RQ+A LVG+V T I+ DDL T T+L+ A+
Sbjct: 187 FRQALAHLLARPVSVAMMEKHRQQAGLSGEH-LVGNVAGSTVIVFDDLISTGQTLLRAAQ 245
Query: 235 ALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTI-PQEKNMKLCPKLQTIDIS 293
A R+AGA+++ A THG+F E ++ + E ++V ++I P ++ +L +D S
Sbjct: 246 ACRQAGASRMLAAATHGLFTTGG-ELFDSGAFERVLVADSIAPFRLPVRCLEQLDIVDTS 304
Query: 294 VMLAEAI 300
++AE +
Sbjct: 305 ALVAELL 311
>UniRef50_O83317 Cluster: Phosphoribosyl pyrophosphate synthetase;
n=2; Treponema|Rep: Phosphoribosyl pyrophosphate
synthetase - Treponema pallidum
Length = 421
Score = 132 bits (319), Expect = 1e-29
Identities = 100/309 (32%), Positives = 163/309 (52%), Gaps = 33/309 (10%)
Query: 35 FSNKETNVEIGESVRGEDVYIVQ-----------SGCGE----INDNLMELFIMINACKI 79
F N E +I E +RG+DV+I Q +G + +ND++M L + I+A +
Sbjct: 92 FLNGELKTQINECIRGKDVFIFQDVENHQPVLVNNGKSKKIFSVNDHVMMLIVTIDAVRH 151
Query: 80 ASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFFN 139
A A RVT V+P +PYSRQ KK R +TA LL ++ G H++T+DLH+ +I+ F+
Sbjct: 152 AGAGRVTLVLPTYPYSRQHKK-CGREGLTAGLLGSVYEYLGVSHIVTLDLHSREIENAFH 210
Query: 140 -IPVDNLYAEPAITKWIK--ENIPEWKSS-VMVSPDAGGVKRMTGIADRLDIDFAIIHKE 195
++NL+A I + + EN+ + V+V+PD+G V+R + L A+I+K
Sbjct: 211 RTRLENLHASYQIIRELAKIENLSDPDIPFVVVAPDSGAVERNKFYSSGLKKPLAMIYKV 270
Query: 196 RQRA----NEGDSTV----LVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAF 247
R + N S + L+GDV+ KTA + DD+ + T+LK E L+ GA ++ A
Sbjct: 271 RDYSVVAQNAKQSNIVEINLLGDVEGKTAFIADDMLGSGGTMLKAMEFLKSRGAKQVIAA 330
Query: 248 LTHGIFAGNAIEKINNS----SLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRRT 303
++ F GNA+E + + I+ TN + + +T D+S + A I R
Sbjct: 331 VSLPFFTGNALELFDEAYEKRYFSRIIGTNAVFHTQLSHKQWYTET-DVSGLFARVIARI 389
Query: 304 HYAESVSYL 312
H+ +S+S L
Sbjct: 390 HHNQSLSSL 398
>UniRef50_Q660Y0 Cluster: Phosphoribosyl pyrophosphate synthetase;
n=3; Borrelia burgdorferi group|Rep: Phosphoribosyl
pyrophosphate synthetase - Borrelia garinii
Length = 406
Score = 131 bits (317), Expect = 2e-29
Identities = 93/295 (31%), Positives = 149/295 (50%), Gaps = 29/295 (9%)
Query: 34 KFSNKETNVEIGESVRGEDVYIVQSGCGE--------------INDNLMELFIMINACKI 79
KF+N E EI +++R +D++IVQ +ND++M L I+AC
Sbjct: 87 KFANGEFKTEILKTIRNKDIFIVQDVANTYEVEINSSEKIIMTVNDHIMNLMTTIDACMQ 146
Query: 80 ASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFF- 138
A A+ V+ ++P +PYSRQDKK SR +TA L+ + G H++T+D+H+ I+ F
Sbjct: 147 AKANSVSVIIPSYPYSRQDKKH-SRECLTASLIGRFLEELGIRHILTLDIHSKAIENVFR 205
Query: 139 NIPVDNLYAEPAITKWIKENIPEWKSS-VMVSPDAGGVKRMTGIADRLDIDFAIIHKERQ 197
+ +NL I K + + I S+ V+VSPD G V R A L A+++KER
Sbjct: 206 KVYFENLNVSYEIFKSLGDLIDIRDSNLVIVSPDTGAVSRNKFFASSLKSPLALLYKERD 265
Query: 198 RA----NEGDS----TVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLT 249
+ + DS T L+GDV+ K M DD+ T T++K + L+ GA KI ++
Sbjct: 266 YSRVSNDVADSNISVTKLLGDVEGKNVFMSDDMLATGGTLIKAMKLLKSMGAKKIICGIS 325
Query: 250 HGIFAGNAIEKINNSSLEA----IVVTNTIPQEKNMKLCPKLQTIDISVMLAEAI 300
F G+AI+ + + E I+ TN + + P +++ + A AI
Sbjct: 326 LPFFNGDAIKYFDKAYEEGYFYKIIGTNAVCHNDELINKPWYHETNVAHLFANAI 380
>UniRef50_Q222A7 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Rhodoferax ferrireducens T118|Rep: Ribose-phosphate
pyrophosphokinase - Rhodoferax ferrireducens (strain DSM
15236 / ATCC BAA-621 / T118)
Length = 328
Score = 128 bits (309), Expect = 2e-28
Identities = 83/310 (26%), Positives = 153/310 (49%), Gaps = 15/310 (4%)
Query: 6 VFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEI-- 63
+++ S A+ + A LG+ L ++F + E + RG D ++V S G+
Sbjct: 12 LYSLDSDDTFAQGLAASLGVKLAPHEYRRFEDGEHKLRPLLDPRGSDTFVVHSLHGDAQN 71
Query: 64 --NDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGA 121
+D L +L + I + A+RV AVVP Y+R+D++ K P++ + +A L G
Sbjct: 72 SPHDKLCQLLMFIATLREHGAARVAAVVPYLAYARKDRQTKPFDPVSLRYVAQLFEAVGT 131
Query: 122 DHVITIDLH-ASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTG 180
++ ++ H + Q F P +L A A E + + +V SPD GGVKR
Sbjct: 132 TQLMVLEAHNVAAFQNAFRCPTMHLEAHQAFNAMALELAGDARLAV-ASPDPGGVKRAQL 190
Query: 181 IADRLD------IDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAE 234
+ L+ + FA++ K R ++ G+V +++DDL + +T+ + A
Sbjct: 191 WRESLETTLLRPVGFAMVDKRRSAGVVSSENLVAGEVDGMRVLLLDDLIASGETMRRAAL 250
Query: 235 ALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCP---KLQTID 291
ALR++GA ++ A + HG+F G+A + + + S+ I++T+++P + C KL
Sbjct: 251 ALRQSGAREVLACVAHGLFTGSAAQVLTDDSIARIIITDSVPPFRLPLACAARRKLSIAS 310
Query: 292 ISVMLAEAIR 301
+ A+AI+
Sbjct: 311 AVPLFAQAIK 320
>UniRef50_A7DQD3 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Ribose-phosphate pyrophosphokinase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 292
Score = 125 bits (302), Expect = 1e-27
Identities = 80/298 (26%), Positives = 148/298 (49%), Gaps = 12/298 (4%)
Query: 4 IKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEI 63
+ V G S D+ K + ++ NL ++ + F + E+ + + ++ +VQS +
Sbjct: 5 LSVICGKSSEDLGKKLARKIKANLVKSEVRIFPDGESKITLKGNISKRKSIVVQSIYPPV 64
Query: 64 NDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADH 123
+ NL++ +I+ K S S V V+P Y+RQD++ +T K+LA L AGA
Sbjct: 65 DTNLIQALSLISKAKETS-SEVIVVIPYMGYARQDREFLPGEIVTMKVLAKLFKGAGASK 123
Query: 124 VITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIAD 183
+I +D+H+ +F I N+ A P + + K+ K+ ++VSPD GG +R A
Sbjct: 124 LIAVDIHSLIGLKYFTIKSKNVSAVPDLAAYFKK--LSLKNPLVVSPDQGGKERAKEFAK 181
Query: 184 RLDIDFAIIHKERQR-ANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGAN 242
+ I+F + K+R R + +V + I+VDD+ T +I+ + L++
Sbjct: 182 EMGIEFIALQKKRDRKTGKVQIKTKQANVIGRDLILVDDMISTGGSIVNATKFLKKEKCK 241
Query: 243 KIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAI 300
+++ TH + +A +KI S + I+ NTIP ++ +D+S +A+AI
Sbjct: 242 RVFVACTHALLMNDAEKKIKKSGVTKIISANTIPGNTSI--------VDVSNTIAKAI 291
>UniRef50_Q58761 Cluster: Ribose-phosphate pyrophosphokinase; n=7;
Methanococcales|Rep: Ribose-phosphate pyrophosphokinase
- Methanococcus jannaschii
Length = 284
Score = 121 bits (292), Expect = 2e-26
Identities = 73/273 (26%), Positives = 136/273 (49%), Gaps = 5/273 (1%)
Query: 6 VFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEIND 65
V +GS ++A + L L R K+F + E V I + + ++ I+ + + ND
Sbjct: 3 VVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVIINTQKNQ-ND 61
Query: 66 NLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVI 125
++E ++ +A + ++T V P Y+RQDKK I+ + LA + S D +I
Sbjct: 62 AIVETILLCDALRDEGVKKITLVAPYLAYARQDKKFNPGEAISIRALAKIYSNI-VDKLI 120
Query: 126 TIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRL 185
TI+ H + I+ FF IP A P + +++K+ + + ++++PD G ++ + L
Sbjct: 121 TINPHETHIKDFFTIPFIYGDAVPKLAEYVKDKLND---PIVLAPDKGALEFAKTASKIL 177
Query: 186 DIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIY 245
+ ++ + K R E D K++ +VDD+ T T+ + L+E GA KI
Sbjct: 178 NAEYDYLEKTRLSPTEIQIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKKII 237
Query: 246 AFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQE 278
A H + G+A+ K+ ++ +E +V T+T E
Sbjct: 238 AACVHPVLIGDALNKLYSAGVEEVVGTDTYLSE 270
>UniRef50_Q12265 Cluster: Probable ribose-phosphate
pyrophosphokinase 5; n=6; Saccharomycetales|Rep:
Probable ribose-phosphate pyrophosphokinase 5 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 496
Score = 121 bits (292), Expect = 2e-26
Identities = 52/112 (46%), Positives = 84/112 (75%), Gaps = 2/112 (1%)
Query: 204 STVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINN 263
+T+LVGDV+NK I+VDDL DT TI + A+ L++ G+ K+YA +THG+F+G+A+E+I
Sbjct: 381 TTMLVGDVRNKVCIIVDDLVDTSYTITRAAKLLKDQGSTKVYALITHGVFSGDALERIGQ 440
Query: 264 SSLEAIVVTNTIPQEKNMKLCPK--LQTIDISVMLAEAIRRTHYAESVSYLF 313
SS++ ++++NT+PQ++ ++ K + ID+S ++ EAIRR H ES+S LF
Sbjct: 441 SSIDKLIISNTVPQDRTLQYLGKDRVDVIDVSCIIGEAIRRIHNGESISMLF 492
Score = 118 bits (285), Expect = 2e-25
Identities = 52/87 (59%), Positives = 69/87 (79%)
Query: 111 LLANLISVAGADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSP 170
L+A+L+S AGADHVIT+DLH Q GFF+IPVDNLY +P +I+ IP+++ +V+VSP
Sbjct: 225 LIAHLLSAAGADHVITMDLHDPQFPGFFDIPVDNLYCKPIAQNYIQHRIPDYQDAVIVSP 284
Query: 171 DAGGVKRMTGIADRLDIDFAIIHKERQ 197
DAGG KR T IAD L++ FA+IHKER+
Sbjct: 285 DAGGAKRATAIADALELSFALIHKERR 311
Score = 114 bits (275), Expect = 2e-24
Identities = 54/97 (55%), Positives = 69/97 (71%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGC 60
M NI VF G SHP++ I L ++ + KFSN ETN+ + ESVR +DVYI+QSGC
Sbjct: 3 MSNIVVFGGDSHPELVTKICENLDIHPSKVELGKFSNGETNIALRESVREKDVYIIQSGC 62
Query: 61 GEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQ 97
G++ND M+L I+I+ACK ASASRVTAV+P YSRQ
Sbjct: 63 GQVNDTFMQLLILISACKSASASRVTAVMPYLCYSRQ 99
>UniRef50_Q6Z2L5-2 Cluster: Isoform 2 of Q6Z2L5 ; n=1; Oryza sativa
(japonica cultivar-group)|Rep: Isoform 2 of Q6Z2L5 -
Oryza sativa subsp. japonica (Rice)
Length = 365
Score = 121 bits (291), Expect = 3e-26
Identities = 55/121 (45%), Positives = 87/121 (71%)
Query: 4 IKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEI 63
+++F+G+++P +++ I + LGL LG+ K+F++ E V++ ESVRG DV++VQ C
Sbjct: 80 LRIFSGTANPSLSQEIASYLGLELGKINIKRFADGEIYVQLQESVRGCDVFLVQPTCPPA 139
Query: 64 NDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADH 123
N+NLMEL IMI+AC+ ASA +TAV+P F Y+R D+K + R I AKL+AN+I+ D+
Sbjct: 140 NENLMELLIMIDACRRASAKNITAVIPYFGYARADRKSQGRESIAAKLVANMITPVILDY 199
Query: 124 V 124
+
Sbjct: 200 L 200
Score = 118 bits (285), Expect = 2e-25
Identities = 60/147 (40%), Positives = 91/147 (61%), Gaps = 2/147 (1%)
Query: 166 VMVSPDAGGVKRMTGIADRL-DIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLAD 224
V+VSPD GGV R A +L D AI+ K R N + L+GDV+ K A+M+DD+ D
Sbjct: 211 VVVSPDVGGVARARAFAKKLSDAPLAIVDKRRHGHNVAEVMNLIGDVRGKVAVMMDDMID 270
Query: 225 TCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLC 284
T TI KGAE L + GA ++YA TH +F+ AIE++++ + +++TNTIP +++ K
Sbjct: 271 TAGTIAKGAELLHQEGAREVYACCTHAVFSPPAIERLSSGLFQEVIITNTIPLKED-KSF 329
Query: 285 PKLQTIDISVMLAEAIRRTHYAESVSY 311
P+L + ++ +L E I R H SV +
Sbjct: 330 PQLTILSVANLLGETIWRVHDDCSVGH 356
>UniRef50_A3H7E6 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Caldivirga maquilingensis IC-167|Rep: Ribose-phosphate
pyrophosphokinase - Caldivirga maquilingensis IC-167
Length = 286
Score = 119 bits (286), Expect = 1e-25
Identities = 75/267 (28%), Positives = 130/267 (48%), Gaps = 15/267 (5%)
Query: 14 DIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIM 73
D+ + +R+G T K F + E + + +V+G DV V + L+ + ++
Sbjct: 13 DLGPNVASRIGAEAREITRKVFPDGEQYIRVEANVKGSDVLYVTRLYPNQDQGLIRVMLL 72
Query: 74 INACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQ 133
++A K A+RV +P PY+RQD++ PI+ ++ N++ G D++ +D+H Q
Sbjct: 73 LDAVKGLGAARVGLFIPYMPYARQDRRFLEGEPISINVILNVLKGLGVDYLYVVDIHKPQ 132
Query: 134 ----IQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDF 189
GF N+ LYA E + V++SPD G + R +A L +++
Sbjct: 133 SLEGYPGFINLKPFKLYA---------EGLGGLSKPVVISPDLGSLWRAEELAKALGVEY 183
Query: 190 AIIHKERQR-ANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFL 248
+ K R R + E T+ +VK K +++DD+ T TI+ A LR GA I
Sbjct: 184 DYLEKHRDRYSGEVSFTLRNLNVKGKDVVIIDDIISTGGTIIGAAGMLRSMGATSINVIA 243
Query: 249 THGIFAGNAIEKINNSSLEAIVVTNTI 275
TH I G+A K+ +++ I +N+I
Sbjct: 244 THCIMIGDAEAKL-TKAVDKIHCSNSI 269
>UniRef50_Q97Z86 Cluster: Ribose-phosphate pyrophosphokinase; n=5;
Sulfolobaceae|Rep: Ribose-phosphate pyrophosphokinase -
Sulfolobus solfataricus
Length = 291
Score = 119 bits (286), Expect = 1e-25
Identities = 74/293 (25%), Positives = 150/293 (51%), Gaps = 8/293 (2%)
Query: 6 VFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEIND 65
+ GS+ I +++ L + L + K F + E+ + + S+R E+V +VQ+ +
Sbjct: 3 IIGGSATNGIDESLSKILSIPLVKVENKIFPDGESYIRVPSSIRDEEVLLVQTTDYPQDK 62
Query: 66 NLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVI 125
+L+ELF++ + A ++TA+VP YSRQD++ K I+ K + +++S G + ++
Sbjct: 63 HLIELFLIAETIRDLGAKKLTAIVPYLAYSRQDRRFKDGEAISIKTILHILSEVGVNTLV 122
Query: 126 TIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRL 185
++ H + +F + ++ I + IKE I + +++PD G + R IA+ +
Sbjct: 123 VVEPHKPEELSYFKGELKIVHPYHQIARKIKEII---EDPFILAPDRGALDRARKIAEEI 179
Query: 186 DIDFAIIHKERQRANEGDSTVLVG---DVKNKTAIMVDDLADTCDTILKGAEALREAGAN 242
+ ++ I KER R G+ + ++K K +++DD+ T TI++ GA
Sbjct: 180 NAPYSYIEKERDRTT-GEVRIKEAPNINLKGKDVVIIDDIISTGGTIVQATRLAYSLGAK 238
Query: 243 KIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTI-PQEKNMKLCPKLQTIDISV 294
+ A H + G A E++ ++ ++ TNTI +K++ Q+I +S+
Sbjct: 239 SVTAAAIHLLLVGGAKERLREVGVKTLIGTNTINVNDKDIITIDVSQSIALSL 291
>UniRef50_A4WYL1 Cluster: Putative uncharacterized protein; n=1;
Rhodobacter sphaeroides ATCC 17025|Rep: Putative
uncharacterized protein - Rhodobacter sphaeroides ATCC
17025
Length = 347
Score = 118 bits (284), Expect = 2e-25
Identities = 84/306 (27%), Positives = 152/306 (49%), Gaps = 20/306 (6%)
Query: 11 SHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVY---IVQSG-CGEINDN 66
SHP + + R GL++ + FS E + SVRG +V ++ +G G +ND
Sbjct: 34 SHP-LGHAVARRAGLSVAMHEARAFSGGEHKLRPLVSVRGHEVCLFSVLHAGEVGSVNDA 92
Query: 67 LMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVIT 126
L+ L + C+ A+RV V P PY R+D++ K+R P+ +A LI G D +IT
Sbjct: 93 LVRLLLFAACCRTNGAARVLIVSPWLPYMRKDRQTKARDPVNTAGVARLIEAVGVDGLIT 152
Query: 127 IDLH-ASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRL 185
+++H + Q F +L I + +VSPD GGVKR + D +
Sbjct: 153 LEVHNLAAFQNAFRCATVHLDTCRLFATEILSR-SAGRPLCLVSPDGGGVKRAALLRDAV 211
Query: 186 D------IDFAIIHKER-QRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALRE 238
+ + F + K R + GD + G+V+ +T +VDD+ ++ T+L+ A A E
Sbjct: 212 EQVSTRPVGFGFMEKHRSEGVVSGD--LFAGEVEGRTVWIVDDMIESGGTLLRAARACAE 269
Query: 239 AGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAE 298
GA +++ TH + A A+ ++ + S+ ++ VT++ + + P+L + ++ ++
Sbjct: 270 RGAAEVHLVATHLVDAA-AVVRLADPSVGSLTVTDS---AVSAEPTPQLHCLSVAPLIGA 325
Query: 299 AIRRTH 304
A+ + H
Sbjct: 326 ALAQIH 331
>UniRef50_A4CGY8 Cluster: Phosphoribosylpyrophosphate synthetase;
n=1; Robiginitalea biformata HTCC2501|Rep:
Phosphoribosylpyrophosphate synthetase - Robiginitalea
biformata HTCC2501
Length = 297
Score = 116 bits (280), Expect = 6e-25
Identities = 72/279 (25%), Positives = 139/279 (49%), Gaps = 9/279 (3%)
Query: 6 VFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEIND 65
+F+ + ++ + + ++ +G +KF + E+ I V+G+ V +V + E +
Sbjct: 5 LFSLPGNQELTELLAKKMNAEIGECAIRKFPDGESYTRILSDVKGKCVVLVCT-LHEPDV 63
Query: 66 NLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVI 125
L+ L+ + + K A V P Y RQDK +++ LIS AD +
Sbjct: 64 KLLPLYFLSHTAKSLGAMCTCLVAPYLAYMRQDKVFNDGEGVSSTYFGKLIS-GFADSIT 122
Query: 126 TIDLHASQIQGF---FNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIA 182
T+D H +I ++IP ++A AI+K+I ENI + V++ PD+ + ++ +A
Sbjct: 123 TVDPHLHRISSLGEVYDIPNRVIHAADAISKYINENI---HNPVLIGPDSESEQWVSDVA 179
Query: 183 DRLDIDFAIIHKERQRANEGDSTVL-VGDVKNKTAIMVDDLADTCDTILKGAEALREAGA 241
+ ++ F ++ K R + + +V V K T ++VDD+ T T+++ E L+ AG
Sbjct: 180 KKAEVPFTVLQKVRHGDRDVEVSVPNVAKYKVSTPVLVDDIISTAQTMIETTEHLKNAGM 239
Query: 242 NKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKN 280
H +F+GNA + + ++ ++ I+ NTIP + N
Sbjct: 240 KPAICIGIHAVFSGNAYQDLWDAHVKDIITCNTIPHQSN 278
>UniRef50_Q8ZU24 Cluster: Ribose-phosphate pyrophosphokinase; n=4;
Pyrobaculum|Rep: Ribose-phosphate pyrophosphokinase -
Pyrobaculum aerophilum
Length = 284
Score = 115 bits (277), Expect = 1e-24
Identities = 76/248 (30%), Positives = 131/248 (52%), Gaps = 14/248 (5%)
Query: 35 FSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMINACKIASASRVTAVVPCFPY 94
F + E V + E+ RGE V +V +NDNL++LF+ I+A A AS++ V+P PY
Sbjct: 29 FPDGEVLVRLPEA-RGE-VAVVARLYPAVNDNLIKLFLTIDALNDAGASKIILVIPYMPY 86
Query: 95 SRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFF-NIPVDNLYAEPAITK 153
+RQD++ + PI++K + L++ +IT+DLH + + + + NLY K
Sbjct: 87 ARQDRRFRPGEPISSKTVLKLLAHLNVFGIITVDLHKGYVAEYAPRLVIKNLYPAEEFAK 146
Query: 154 WIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVG---D 210
+ V++SPD G V R +A L + + K R R+ G T++ D
Sbjct: 147 AL------GGVDVVLSPDFGSVHRAEAVARLLQVPYTYFEKYRDRST-GAITLIPRQDVD 199
Query: 211 VKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIV 270
++NK +VDD+ T T++ +A + GA ++YA +TH +A E++ S ++ I+
Sbjct: 200 LRNKRVAIVDDILSTGGTLVDACKAAKTLGAAEVYAAITHCQLLKDARERV-RSCVDKII 258
Query: 271 VTNTIPQE 278
T+T+ E
Sbjct: 259 CTDTVLNE 266
>UniRef50_A1ZM86 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Microscilla marina ATCC 23134|Rep: Ribose-phosphate
pyrophosphokinase - Microscilla marina ATCC 23134
Length = 306
Score = 114 bits (275), Expect = 2e-24
Identities = 86/284 (30%), Positives = 139/284 (48%), Gaps = 14/284 (4%)
Query: 28 GRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDN-LMELFIMINACKIASASRVT 86
G + F + E I V G+DV IV G I D+ +ELF M A + +T
Sbjct: 27 GATEVRFFPDGERYQRILSDVNGKDVVIVG---GTIADSDTLELFDMACAIEKYGGKTLT 83
Query: 87 AVVPCFPYSRQDKKEKSRAPITAKLLANLIS---VAG-ADHVITIDLHASQIQGFF--NI 140
V+P F YS ++ K +T K A L+S + G + V+ DLH S +Q +F NI
Sbjct: 84 LVIPYFGYSTMERAVKPGEVVTGKSRARLLSAIPITGRGNQVLLFDLHTSGLQHYFEGNI 143
Query: 141 PVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRAN 200
++Y + + + +E E ++ D G K + +A+ + I A + K R A
Sbjct: 144 RPVHIYCKDLVIEAARELGGE--DFILACTDTGRAKWVESLANDMGIFAAFVFKRRISAE 201
Query: 201 EGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEK 260
T + DVK K ++ DD+ T +++ A+A ++AGA KI A THGIF NA+E+
Sbjct: 202 NTQITGINADVKGKNVVIYDDMIRTGGSLINAAQAYKDAGATKISAITTHGIFPNNAMER 261
Query: 261 INNSSL-EAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRRT 303
+ S L E +V T++ P ++ P L+ I ++ + + T
Sbjct: 262 LQKSGLFECVVSTDSHPNAVKVE-SPLLKIKSIDRLIIDKLEGT 304
>UniRef50_Q6L0L1 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
Thermoplasmatales|Rep: Ribose-phosphate
pyrophosphokinase - Picrophilus torridus
Length = 288
Score = 114 bits (275), Expect = 2e-24
Identities = 69/270 (25%), Positives = 137/270 (50%), Gaps = 8/270 (2%)
Query: 6 VFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEIND 65
+ SS + ++ ++L + T K+F + E V I ++ DV ++ G +
Sbjct: 4 IVPSSSSMKLTSSLASKLNAEIANVTRKRFPDGEMYVRIETDLKDRDVIVL--GNTSHDS 61
Query: 66 NLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVI 125
+L+E +++NA + + AV+P F Y+RQ + P+++K+ I AD ++
Sbjct: 62 DLIEYLLLLNAAYEEKPATLNAVIPYFGYARQHMRYNPGEPVSSKVFTKAIENF-ADSIM 120
Query: 126 TIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRL 185
+++H + F P N+ +I + K + ++ ++SPD GG +R IA L
Sbjct: 121 AVEIHDEETLKFSAKPFTNVKVYDSIADYHKNHDIDY----VISPDDGGYERAKSIAKYL 176
Query: 186 DIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIY 245
+D I K+R + + + D +N+ ++VDD+ T T++K + L+++GA KIY
Sbjct: 177 KVDAYYIEKKRIDSRTVEMKMPDIDSRNRNILIVDDMISTGGTVIKASRILKDSGAKKIY 236
Query: 246 AFLTHGIFAGNAIEKINNSSLEAIVVTNTI 275
HG+F+ N+ I +++ + V++TI
Sbjct: 237 VSAVHGVFSLNSAANI-MENVDDLSVSDTI 265
>UniRef50_Q8IE40 Cluster: Ribose-phosphate pyrophosphokinase,
putative; n=4; Plasmodium|Rep: Ribose-phosphate
pyrophosphokinase, putative - Plasmodium falciparum
(isolate 3D7)
Length = 560
Score = 112 bits (269), Expect = 1e-23
Identities = 65/186 (34%), Positives = 109/186 (58%), Gaps = 13/186 (6%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQS---G 59
N+++F+ +SH ++A I + LG+ LGRA KFS+ E ++I + VRG D+YI+ S G
Sbjct: 175 NMQIFSSNSHHELANEICSNLGIGLGRAYVGKFSDGEIALQIMDEVRGRDIYIIHSTPAG 234
Query: 60 CGEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSR---APITAKLLANLI 116
+++ LMELF+ I+ + +SA +VTAV+P YSRQ K + A +A L+
Sbjct: 235 GKDVHSRLMELFLFISTLRRSSAKKVTAVIPYLNYSRQTKHLDDHNYVHSLGAPEIAILL 294
Query: 117 SVAGADHVITIDLHASQIQGF-----FNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPD 171
G D +I++DLH ++I+GF F P+ N+ + ++ K+ + ++ V+VS D
Sbjct: 295 QACGVDSIISVDLHNARIEGFSTGKKFQPPLMNINPQSLAVEYFKKK--KLRNPVVVSID 352
Query: 172 AGGVKR 177
G +R
Sbjct: 353 NEGAER 358
Score = 94.7 bits (225), Expect = 3e-18
Identities = 47/122 (38%), Positives = 72/122 (59%), Gaps = 1/122 (0%)
Query: 191 IIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTH 250
I+ K+ + + +VGD+K I+VDD+ DT + K A L+ AGA KIY + TH
Sbjct: 428 IVDKKENDMYDKEKFTIVGDIKGCDCILVDDIIDTGEKSQKVAAILKNAGARKIYLYATH 487
Query: 251 GIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRRTHYAESVS 310
I + IEKINNS ++ +V TNTI N+ C KL + ++ ++AE I+R H +S++
Sbjct: 488 AILSDGCIEKINNSCIDEVVTTNTIHIPSNI-CCEKLHILSVAKLVAEGIKRAHNEQSLN 546
Query: 311 YL 312
L
Sbjct: 547 AL 548
>UniRef50_O28853 Cluster: Ribose-phosphate pyrophosphokinase 2; n=1;
Archaeoglobus fulgidus|Rep: Ribose-phosphate
pyrophosphokinase 2 - Archaeoglobus fulgidus
Length = 271
Score = 111 bits (268), Expect = 2e-23
Identities = 78/272 (28%), Positives = 136/272 (50%), Gaps = 18/272 (6%)
Query: 4 IKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEI 63
+K+ S P +A+ + G+ +G A KKF + E V + E E V + G I
Sbjct: 1 MKIIPCPSSPLLARRVAEAAGIEIGGAVFKKFPDGELYVRVMEK---EGVVV-----GSI 52
Query: 64 NDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADH 123
N N +L +I A + ++ AVVP Y+RQDK + ++ K++A ++ + AD
Sbjct: 53 NSN-EDLIALIFALDVLENAK--AVVPYMGYARQDKVFQEGEAVSIKIVAEMLE-SRADE 108
Query: 124 VITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIAD 183
V+T+++H+S F+ + NL A P + ++ K VM+SPD G ++R+ A
Sbjct: 109 VVTVNIHSSDAASHFS-KLKNLDAMPLVGEYFAG-----KDVVMISPDKGSMERVKTAAK 162
Query: 184 RLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANK 243
++ + K R A + T DV+ + ++VDD+ T T+ + A L GA
Sbjct: 163 HAGCEWDYMEKRRIDATTVEITPKTIDVEGRDVVIVDDIISTGGTVAEAARILYGLGAKS 222
Query: 244 IYAFLTHGIFAGNAIEKINNSSLEAIVVTNTI 275
+ A H + A NA K+ N+ ++ I+ T+T+
Sbjct: 223 VSAACVHAVLAENAAIKLFNAGIKDIIATDTV 254
>UniRef50_A0RYR1 Cluster: Phosphoribosylpyrophosphate synthetase;
n=1; Cenarchaeum symbiosum|Rep:
Phosphoribosylpyrophosphate synthetase - Cenarchaeum
symbiosum
Length = 283
Score = 110 bits (264), Expect = 5e-23
Identities = 71/243 (29%), Positives = 118/243 (48%), Gaps = 5/243 (2%)
Query: 35 FSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMINACKIASASRVTAVVPCFPY 94
F++ E+ + + R +VQS + NL++ ++++ A +V AVVP Y
Sbjct: 4 FADGESRLTLDAPRRRGTAVVVQSTQPPADTNLLQALLLVHKAGCI-ADKVVAVVPYMGY 62
Query: 95 SRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFFNIPVDNLYAEPAITKW 154
+RQD++ +T +++A L AGA V +D+H+ G F N+ A PA+ +
Sbjct: 63 ARQDREFLRGEIVTIEVVAGLFRAAGARRVYIVDMHSMAGLGLFGGLAVNVPAAPALAEH 122
Query: 155 IKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVG--DVK 212
K ++VSPDAGG R A L A + K R R + G D +
Sbjct: 123 FGRM--RLKDPLVVSPDAGGTARAAEFAGLLGTGHAALEKRRNRRTGSIAVSGPGLPDTE 180
Query: 213 NKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVT 272
N+ ++VDD+ + +I+K A L+ G +IY TH + +A +I + +E IV T
Sbjct: 181 NRDVVLVDDMISSGGSIIKAAGFLKGRGCGRIYVACTHALLVNDAERRIAEAGVEKIVGT 240
Query: 273 NTI 275
NT+
Sbjct: 241 NTV 243
>UniRef50_Q0W4S8 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
uncultured methanogenic archaeon RC-I|Rep:
Ribose-phosphate pyrophosphokinase - Uncultured
methanogenic archaeon RC-I
Length = 298
Score = 108 bits (259), Expect = 2e-22
Identities = 69/282 (24%), Positives = 132/282 (46%), Gaps = 9/282 (3%)
Query: 6 VFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEIND 65
+ GSS P +AK+I R+G + +KF + E +V G+ + V VQ+ ND
Sbjct: 5 IIAGSSVPGLAKSIARRMGTKAHFPSIEKFPDGEIHVVEGDYTPAQTVVYVQTMHPHPND 64
Query: 66 NLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVI 125
L+E+ + ++ K A RV AV+P Y RQD + + + + ++ AG + ++
Sbjct: 65 MLVEMMLTVDLLKELGAERVIAVIPYVGYMRQDARHVKGEAVAIRTMLKMLDFAGVNDIV 124
Query: 126 TIDLH-----ASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTG 180
+D+H ++ F I + + A + + + + ++V PD+ +
Sbjct: 125 GVDMHLHRLGIEELASFSRIKIHEVSAVELLAARAGKGL---TTPLVVGPDSESERWAAA 181
Query: 181 IADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAG 240
A L D+ ++ K R A E + VK + +++DD+ T TI ++L+ G
Sbjct: 182 AARVLGTDYDVLEKHRLSAREIEHRPRSMAVKGRDVLIIDDIVSTGGTIKDVIKSLKAQG 241
Query: 241 ANKIYAFLTHGIFAG-NAIEKINNSSLEAIVVTNTIPQEKNM 281
A ++ TH + + +++ + + +E IV TNTI E +
Sbjct: 242 AGQVNVACTHAVLSDIDSLTGLYRTGMEEIVSTNTINNESGI 283
>UniRef50_Q9HLV6 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
Thermoplasma|Rep: Ribose-phosphate pyrophosphokinase -
Thermoplasma acidophilum
Length = 286
Score = 107 bits (257), Expect = 4e-22
Identities = 66/272 (24%), Positives = 138/272 (50%), Gaps = 8/272 (2%)
Query: 4 IKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEI 63
+K+ S +A+ + +L L ++F + E V + GEDV+I+ G
Sbjct: 1 MKIIGLQSSSSLARKVAEQLHSELVLPEERRFPDGELYVRYDADLNGEDVFII--GNTHT 58
Query: 64 NDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADH 123
+ ++E+ + ++A + V + P + Y+RQ ++ + PI++++ + + + +
Sbjct: 59 DAEIIEMILSLSAVRDYQVKSVNIIAPYYGYARQHQRYRRGEPISSQIFTEIFA-SYSTS 117
Query: 124 VITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIAD 183
+ T+D+H Q + + +L+A+ +I + + ++ +VSPD GG++R+ +A+
Sbjct: 118 IATVDIHDEQTLSYSKVRFTDLHADRSIIDFYRHVDIDY----VVSPDDGGLQRVKHVAE 173
Query: 184 RLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANK 243
L + I K+R + D+ K +++DD+ T TI K + LR+ GA+K
Sbjct: 174 ALGKKYFYIEKKRIDDRTVEMKAPDIDLNGKKVLILDDIISTGGTIAKSSSILRQKGASK 233
Query: 244 IYAFLTHGIFAGNAIEKINNSSLEAIVVTNTI 275
IY HG+F ++ KI ++ + I VT+T+
Sbjct: 234 IYVSAIHGLFVNSSESKILENA-DEIHVTDTV 264
>UniRef50_Q5ZWR2 Cluster: Ribose-phosphate pyrophosphokinase; n=4;
Legionella pneumophila|Rep: Ribose-phosphate
pyrophosphokinase - Legionella pneumophila subsp.
pneumophila (strain Philadelphia 1 /ATCC 33152 / DSM
7513)
Length = 303
Score = 105 bits (251), Expect = 2e-21
Identities = 66/266 (24%), Positives = 130/266 (48%), Gaps = 9/266 (3%)
Query: 14 DIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIM 73
+IA + L + +G T +F + E ++I V + +V S + ++ ++ L
Sbjct: 13 EIAGRLQESLQVEVGDVTFHRFPDTEWYLKINSEVNNRSLMVVDS-LNQPDEKILPLLFF 71
Query: 74 INACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQ 133
K A +V + P Y RQDK+ IT++ A+++S + D ++TID H +
Sbjct: 72 AKTAKELGARKVGLIAPYLSYLRQDKRFHEGEGITSRYFADILSTS-FDWLMTIDPHLHR 130
Query: 134 ---IQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFA 190
+ ++IP L+A I WIK ++P+ +++ PD + + IA++ +A
Sbjct: 131 YHSLDEIYSIPTFVLHATSMIATWIKHHVPK---PILIGPDMESEQWVADIAEKGSFSYA 187
Query: 191 IIHKERQRANEGDSTV-LVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLT 249
I+ K R+ E +V + ++++ T ++VDD+ T T+++ + L +AG I
Sbjct: 188 ILEKIRRGDKEVTISVPTIPELESSTLVLVDDIISTARTMVETVKHLHQAGGKSIVCIGV 247
Query: 250 HGIFAGNAIEKINNSSLEAIVVTNTI 275
H +FA +A ++ ++ NTI
Sbjct: 248 HALFAEDAYSLLSEMKGVQVITCNTI 273
>UniRef50_A2BKK7 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Hyperthermus butylicus DSM 5456|Rep: Ribose-phosphate
pyrophosphokinase - Hyperthermus butylicus (strain DSM
5456 / JCM 9403)
Length = 222
Score = 104 bits (250), Expect = 3e-21
Identities = 55/185 (29%), Positives = 99/185 (53%), Gaps = 3/185 (1%)
Query: 93 PYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFFNIPVDNLYAEPAIT 152
PY+RQD++ P++ + L ++ +GA+ +T+D+H + +F P N+ PA
Sbjct: 6 PYARQDRRFLRGEPVSVRALFYSLAASGAEAFVTVDIHKTVSLQWFPGPAVNVDPAPAFA 65
Query: 153 KWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTV--LVGD 210
+ ++ + + +++PD G V R +A+RL F + K R R G+ + + D
Sbjct: 66 EKLRPLLEGREKVYVIAPDQGAVGRAKSLAERLGAPFDYLEKVRDRVT-GEIVLRPKLVD 124
Query: 211 VKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIV 270
V +++DD+ T T+ K A L E GA + A THG+FAG A+EK+ + + I+
Sbjct: 125 VSGAAVVLIDDIVSTGGTMAKAARMLYEQGAEVVIAAATHGLFAGEALEKMRKAGIVHIL 184
Query: 271 VTNTI 275
V +T+
Sbjct: 185 VADTV 189
>UniRef50_A1RWZ6 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Thermofilum pendens Hrk 5|Rep: Ribose-phosphate
pyrophosphokinase - Thermofilum pendens (strain Hrk 5)
Length = 276
Score = 104 bits (250), Expect = 3e-21
Identities = 67/247 (27%), Positives = 122/247 (49%), Gaps = 8/247 (3%)
Query: 33 KKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMINACKIASASRVTAVVPCF 92
K F + E V + G + +V S L+EL + + A + V AVVP
Sbjct: 11 KVFPDGEIYVRVPSKPSGVAI-VVSSTHPPQERRLLELLLTVEALSSYAQGSVIAVVPYL 69
Query: 93 PYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQI-QGFFNIPVDNLYAEPAI 151
Y+RQDK+ PI+ K++ + AGA ++ +D+H ++ + +IP N+ I
Sbjct: 70 AYARQDKRFLEGEPISIKVVLKALEAAGASGLLAVDVHQPRVLSEWLSIPSKNVLPFEDI 129
Query: 152 TKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVG-- 209
++ + K++V+++PD G ++R +A+ + DF + KER R G+ V
Sbjct: 130 AGYLYGKV---KNAVVLAPDMGALERARRVAELIGADFDYLVKERDRVT-GEVRVQPKSL 185
Query: 210 DVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAI 269
+V + ++VDD+ T TI A++ GA+ + A TH + A++ + S + +
Sbjct: 186 EVNGRDVVIVDDIISTGKTIALAAKSALAQGASSVTAVCTHAVMVQGALDLLYYSGVREV 245
Query: 270 VVTNTIP 276
V T+T+P
Sbjct: 246 VATDTVP 252
>UniRef50_Q9YAW0 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Aeropyrum pernix|Rep: Ribose-phosphate pyrophosphokinase
- Aeropyrum pernix
Length = 309
Score = 103 bits (247), Expect = 6e-21
Identities = 70/274 (25%), Positives = 134/274 (48%), Gaps = 7/274 (2%)
Query: 9 GSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRG-EDVYIVQSGCGEINDNL 67
GS+ + ++ + +GL L + K F ++E V I + G +VQS + +L
Sbjct: 14 GSASAEFSEGLSRNMGLKLVKPVFKLFPDEEEYVRIEGDISGFTGAIVVQSFERPASRSL 73
Query: 68 MELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITI 127
+ ++ +A K A R+ + P Y+RQD+ P++ + + ++ +G + + +I
Sbjct: 74 VYSLLIADALKEAGVGRIVLMAPYMGYTRQDRVFLPGEPVSVRAVMRALASSGYNALASI 133
Query: 128 DLHASQIQGFFNIPVDNLYAEPAITKWIKEN-IPEWKSSVMVSPDAGGVKRMTGIADRLD 186
++H + +F+ N++ T +KE I ++++V+PD G + R+ +A
Sbjct: 134 EVHKEYVLDYFDGSTLNIFP---FTYMLKETGISCGDNTIIVAPDKGSLPRVERLARETG 190
Query: 187 I-DFAIIHKERQR-ANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKI 244
+ + KER R E D + K AI+VDD+ T TI ++ L E GAN +
Sbjct: 191 CRSYGYLVKERDRITGEVRLAKSTVDPRGKNAIVVDDIISTGGTIALASQWLLENGANSV 250
Query: 245 YAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQE 278
+ H + GNA EK+ + + +V NT+P++
Sbjct: 251 FVLAAHYLGIGNAEEKMMKAGVSRVVTGNTLPRK 284
>UniRef50_A1RX65 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Thermofilum pendens Hrk 5|Rep: Ribose-phosphate
pyrophosphokinase - Thermofilum pendens (strain Hrk 5)
Length = 275
Score = 101 bits (243), Expect = 2e-20
Identities = 73/259 (28%), Positives = 129/259 (49%), Gaps = 14/259 (5%)
Query: 23 LGLNLGRATTKKFSNKETNVEIGESVRGEDV-YIVQSGCGEINDNLMELFIMINACKIAS 81
LGL A + F + E V + + ++ E+V Y+V G N+ L E + + +
Sbjct: 2 LGLKYEVARVRSFPDGELYVRLPQGLKDEEVAYVVCYG-RRPNEALAETVLAVEGLREKG 60
Query: 82 ASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQG---FF 138
A +V V P PY RQD + ++++++A L++ D +IT+D H +I+ F
Sbjct: 61 AEKVVLVAPYLPYLRQDAEFTPGEVVSSRVIARLLAKLDVDALITVDPHLHRIRSLSELF 120
Query: 139 NIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQR 198
P + A P + + ++ E + V+V+PD + AD + + + K+R
Sbjct: 121 PFPAIEVSAMPLLAAFFQK---EHGTGVVVAPDEEAERWAKTFADTIGAPYFVFEKQRM- 176
Query: 199 ANEGDSTVLV-GDVK-NKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGN 256
GD V V G VK +TA++VDD+ T T+ + A+ L EAG IYA +TH + +
Sbjct: 177 ---GDEIVSVTGAVKRGETAVIVDDIVSTGGTLGEVAQKLLEAGFRDIYACVTHALLVQD 233
Query: 257 AIEKINNSSLEAIVVTNTI 275
A +I S ++ + T+++
Sbjct: 234 AEARIFGSGVKEFISTDSV 252
>UniRef50_Q8PUX3 Cluster: Ribose-phosphate pyrophosphokinase; n=6;
Euryarchaeota|Rep: Ribose-phosphate pyrophosphokinase -
Methanosarcina mazei (Methanosarcina frisia)
Length = 295
Score = 101 bits (241), Expect = 3e-20
Identities = 74/286 (25%), Positives = 135/286 (47%), Gaps = 16/286 (5%)
Query: 4 IKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEI 63
+K+ G + +A LG +F + E + I E + E V ++QS
Sbjct: 13 LKIIGGPASQLLASRTARALGTEPVLCEFNRFPDGELYLRIAEEIENEKVTLIQST--PT 70
Query: 64 NDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADH 123
+ + + L +I+AC+ A+ + V+P Y+RQDKK KS P++A+ +A I+ AD
Sbjct: 71 DSDFVALLQLIDACE--GAAEINVVIPYMGYARQDKKFKSGEPVSARAIARCIN---ADR 125
Query: 124 VITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIAD 183
V TI++H + F P +NL A I ++ E ++V+PD G + +A
Sbjct: 126 VFTINIHEKSVLEHFPCPAENLDAAALIGSYVAGFGLE--RPMLVAPDEGARGLVKNVAS 183
Query: 184 RLDIDFAIIHKERQRANEGDSTVLVG---DVKNKTAIMVDDLADTCDTILKGAEALREAG 240
D + K R GD+ V+ DV + ++VDD+ T T+ + L+ G
Sbjct: 184 GHGFDHDHLQKTRL---SGDTVVIKTKNLDVTGRHVVLVDDMIATGGTMAESIRMLKSQG 240
Query: 241 ANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQ-EKNMKLCP 285
A ++ H + NA ++ ++ ++ I+ T+T+ + E + + P
Sbjct: 241 AIDVHLACVHPVLTRNAALRLFHAGVKDIIGTDTLEKAESKLSVAP 286
>UniRef50_Q9HN88 Cluster: Ribose-phosphate pyrophosphokinase; n=5;
Halobacteriaceae|Rep: Ribose-phosphate pyrophosphokinase
- Halobacterium salinarium (Halobacterium halobium)
Length = 281
Score = 99.1 bits (236), Expect = 1e-19
Identities = 72/272 (26%), Positives = 129/272 (47%), Gaps = 11/272 (4%)
Query: 6 VFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEIND 65
+ +GSS +A + A G LG T F + E V + +V GE IV S +D
Sbjct: 2 LLSGSSSQSLAAALAAATGERLGDVTYDSFPDGEQLVTVPPAVDGERAVIVAST--PTSD 59
Query: 66 NLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVI 125
+E+ + +A + A AS + V+P Y+RQD P++A+ +A IS G D V+
Sbjct: 60 AHIEVLQLQDAARDAGASEIITVLPYMGYARQDDAFDPGQPVSARAVARAIS-TGTDRVL 118
Query: 126 TIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRL 185
T++ H + F++P + A P + + ++ + V +SPD G T + D
Sbjct: 119 TVNPHEDGVLECFDVPAAGVDAAPQLAAPLPADLTD---PVFLSPDHGATDLATSVRDAY 175
Query: 186 DIDFAIIHKERQRANEGDSTVLVGDVK--NKTAIMVDDLADTCDTILKGAEALREAGANK 243
H ++ R + D TV +++ + ++ DD+ T T+ + AL + +
Sbjct: 176 GTG-VTDHFQKVRHSGSDVTVEPSEIQTAGRDVVVTDDIVATGTTMSEAITALDDPA--R 232
Query: 244 IYAFLTHGIFAGNAIEKINNSSLEAIVVTNTI 275
++ H + AG+A K+ + +EA+ T+TI
Sbjct: 233 VFVATVHPLLAGSARLKLARAGVEAVYGTDTI 264
>UniRef50_A3CS59 Cluster: Ribose-phosphate pyrophosphokinase; n=4;
Methanomicrobia|Rep: Ribose-phosphate pyrophosphokinase
- Methanoculleus marisnigri (strain ATCC 35101 / DSM
1498 / JR1)
Length = 285
Score = 98.7 bits (235), Expect = 2e-19
Identities = 69/260 (26%), Positives = 124/260 (47%), Gaps = 10/260 (3%)
Query: 15 IAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMI 74
+A + +LG L +F + E ++ E +D ++ S + ND M+ + I
Sbjct: 12 LAARVAEKLGAPLVETKFTRFPDGELYLKCREL---DDETLIVSSIVD-NDMFMQTLLAI 67
Query: 75 NACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQI 134
+A A S+ T VVP YSRQDK+ PI+A+ +A +S AG + V +++H +
Sbjct: 68 DA---ADQSKNTLVVPYLGYSRQDKRFSPGEPISARAVARALS-AGIERVYVVNIHDPGV 123
Query: 135 QGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHK 194
G F +P N+ PA+ ++ + K+ ++++PD G + + +A D + K
Sbjct: 124 LGHFGVPAKNVTIAPAVGGYVGDL--RLKNPLVLAPDEGAIGFASDVAAVGGWDCDHLEK 181
Query: 195 ERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFA 254
R E D + ++VDD+ T T+ A LRE GA I+A HG+
Sbjct: 182 TRLSGEEVRIAPKTIDAAGRDVVIVDDIISTGGTLATAACMLREQGAASIHAACVHGVLT 241
Query: 255 GNAIEKINNSSLEAIVVTNT 274
A ++ + + ++V ++T
Sbjct: 242 SGAYTRLRAAGVSSVVSSDT 261
>UniRef50_A7MKK1 Cluster: Putative uncharacterized protein; n=1;
Enterobacter sakazakii ATCC BAA-894|Rep: Putative
uncharacterized protein - Enterobacter sakazakii ATCC
BAA-894
Length = 285
Score = 97.9 bits (233), Expect = 3e-19
Identities = 71/260 (27%), Positives = 133/260 (51%), Gaps = 17/260 (6%)
Query: 45 GESVRGEDVYIVQSGCGEINDNLMELFIMINACKIASASRVTAV-VPCFPYSRQDKKEKS 103
GE R + +++ + D+ M L + +A + R + + +P PY+RQD+ +
Sbjct: 31 GELPRVASLMRIRAAAMKTMDDFMLLAQLTDAVRQHCDVRFSHLELPWLPYARQDRHMQP 90
Query: 104 RAPITAKLLANLISVAGADHVITIDLH----ASQIQGFFNIPVDNLYAEPAITKWIKENI 159
K+ A ++ G D VI +D H A+ I+ IP + + +K ++ +
Sbjct: 91 GDSFALKVFARQLNTLGFDKVIVLDPHSEAAAAAIENLVAIPQERCLLQ---SKTLERAL 147
Query: 160 PEWKSSVMVSPDAGGVKRMTGIADRLDI-DFAIIHKERQRANEGDST---VLVGDVKNKT 215
+ ++V+PDAG +K++ +A + +FAI+ K+R A G+ T ++ GDVK K
Sbjct: 148 KAGEL-MLVAPDAGALKKIHAVAQAAGVHEFAILTKQRNVAT-GELTGFRLVDGDVKGKA 205
Query: 216 AIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTI 275
++VDDL D T + A+ LR+AGA+ + ++THG+F+ +NN + T+
Sbjct: 206 VLIVDDLCDAGGTFIGSAQVLRDAGASSVSLYVTHGVFSKGVENLLNNGIDKLYTTTSFA 265
Query: 276 PQEKNMKLCPKLQTIDISVM 295
P E + +++ IDI+ +
Sbjct: 266 PAELAQE---RVEMIDINTI 282
>UniRef50_Q11BI1 Cluster: Ribose-phosphate pyrophosphokinase; n=4;
Proteobacteria|Rep: Ribose-phosphate pyrophosphokinase -
Mesorhizobium sp. (strain BNC1)
Length = 326
Score = 97.1 bits (231), Expect = 5e-19
Identities = 65/263 (24%), Positives = 128/263 (48%), Gaps = 14/263 (5%)
Query: 24 GLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMINACKIASAS 83
G LG T++F + ET V I V+ + V +V S +D + L + +A + A
Sbjct: 22 GWELGALATRRFPDGETYVRILSDVKDKAVDLV-STLARPDDGFLRLIFVADAARSLGAR 80
Query: 84 RVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQ---IQGFFNI 140
V + P Y RQD++ + IT++ A L+S + D ++T+D H + + + I
Sbjct: 81 EVNLIAPYLSYMRQDRRFQPGEAITSRSFARLVS-SSFDRLVTVDPHLHRYPALSALYTI 139
Query: 141 PVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRAN 200
P L+A P + WI + + ++V PD + ++ IA R+ A++ K R
Sbjct: 140 PTITLHAAPLLADWIASAV---EKPLIVGPDEESEQWVSAIAARIGAPHAVLRKVRH--G 194
Query: 201 EGDSTVLVGDV---KNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNA 257
+ + + + D+ + + ++ DD+A + T+++ A L G + + H IFA ++
Sbjct: 195 DRNVEIALPDLTGWRGRQPVLADDIASSGHTLIEAARQLPLQGFARPVVAVVHAIFAEDS 254
Query: 258 IEKINNSSLEAIVVTNTIPQEKN 280
+++ + IV ++++P E N
Sbjct: 255 FQRL-APLCDRIVSSDSVPHESN 276
>UniRef50_Q075L4 Cluster: Plastid ribose-phosphate diphosphokinase;
n=1; Prototheca wickerhamii|Rep: Plastid
ribose-phosphate diphosphokinase - Prototheca
wickerhamii
Length = 213
Score = 95.5 bits (227), Expect = 2e-18
Identities = 41/96 (42%), Positives = 70/96 (72%)
Query: 4 IKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEI 63
+++F+G+++P +++ +V LGL LG + K+F++ E V++GES+RG DV+++Q +
Sbjct: 118 LRIFSGTANPGLSQEVVCYLGLELGAISIKRFADGEIYVQVGESIRGCDVFLIQPTAPPV 177
Query: 64 NDNLMELFIMINACKIASASRVTAVVPCFPYSRQDK 99
ND L+EL I I+AC+ ASA +TAV+P F Y+R D+
Sbjct: 178 NDALVELLITIDACRRASARSITAVLPYFGYARADE 213
>UniRef50_Q89QK8 Cluster: Bll3116 protein; n=5;
Bradyrhizobiaceae|Rep: Bll3116 protein - Bradyrhizobium
japonicum
Length = 306
Score = 94.7 bits (225), Expect = 3e-18
Identities = 73/276 (26%), Positives = 129/276 (46%), Gaps = 18/276 (6%)
Query: 14 DIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIM 73
+ AK + ARLGL T +F + E V + + D I+ + + ND L+ L
Sbjct: 14 EAAKRLAARLGLASDEMTLHRFPDGELRVTVAPAA---DTTILYAALDQPNDKLIALLFA 70
Query: 74 INACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQ 133
A + A R+ V P Y RQD + I+ + + L++ D V+T+D H +
Sbjct: 71 AEALRRGGAKRLVLVAPYLCYMRQDIAFHAGEAISQRAMGTLLATI-VDRVVTVDAHLHR 129
Query: 134 IQG----FFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDF 189
F I +NL A PAI + + ++V++ PDA + +A RLD+
Sbjct: 130 TPDIAAVFPGIEAENLSAMPAIANALVAAGID-PATVVIGPDAESEPWVRDLAGRLDLQH 188
Query: 190 AIIHKERQ--RANE---GDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKI 244
+ K R+ R+ E D+ +L G + A+MVDD+ + T++ A+ LR GA+ +
Sbjct: 189 TVARKLRRGDRSVEIDFADAALLAG----RPALMVDDIVSSGTTLMVAAKTLRAMGASAV 244
Query: 245 YAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKN 280
+ +TH +F ++ + +I ++++P N
Sbjct: 245 DSVVTHALFPPAMSAAFADAGIRSIRSSDSVPHPTN 280
>UniRef50_Q2SLU9 Cluster: Phosphoribosylpyrophosphate synthetase;
n=1; Hahella chejuensis KCTC 2396|Rep:
Phosphoribosylpyrophosphate synthetase - Hahella
chejuensis (strain KCTC 2396)
Length = 290
Score = 93.9 bits (223), Expect = 5e-18
Identities = 73/279 (26%), Positives = 133/279 (47%), Gaps = 23/279 (8%)
Query: 12 HPDIAKTIVARLGLNLGRATTKKFSNKETNVEI-GESVRGEDVYIVQSGCGEINDNLMEL 70
HP +A+ + A G+++G ++F + ET + I GE+ + IV + + ++ +
Sbjct: 10 HP-VAERLAAAPGMDVGNYQLRQFPDGETYIRIEGEA---PNKAIVCADLSSPDQKILPV 65
Query: 71 FIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLH 130
+ + +T V P PY RQD + IT++ A +IS A D ++T+D H
Sbjct: 66 LLFAATLRDLGVEHITLVAPYLPYMRQDIRFHPGEGITSRYFARMIS-AHFDRLLTVDPH 124
Query: 131 ASQ---IQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDI 187
+ + ++IP +L A PAI WI+ ++ + V+V PD+ + ++ +A+
Sbjct: 125 LHRYHSLDELYSIPARSLAAAPAIADWIRTHLDK---PVIVGPDSESDQWVSHVAELAGC 181
Query: 188 DFAIIHKERQRANEGDSTVLVGDVKNK------TAIMVDDLADTCDTILKGAEALREAGA 241
D + K R GD V++ D +N + +MVDD+ T T+++ A L AG
Sbjct: 182 DRLVFSKTRL----GDKDVII-DARNAEKYREYSPVMVDDIISTGRTMIEAAAELAAAGL 236
Query: 242 NKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKN 280
++ H +FA +A I + + V NT+ N
Sbjct: 237 HQPVCIGVHAVFADDAYHAIQAAPIARTVSCNTVIHATN 275
>UniRef50_Q12E98 Cluster: Ribose-phosphate pyrophosphokinase; n=3;
Comamonadaceae|Rep: Ribose-phosphate pyrophosphokinase -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 301
Score = 91.1 bits (216), Expect = 3e-17
Identities = 65/266 (24%), Positives = 123/266 (46%), Gaps = 10/266 (3%)
Query: 34 KFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMINACKIASASRVTAVVPCFP 93
+F + ET V I V G V + S + + + L +A + ASRV V P
Sbjct: 31 RFPDGETLVRIDAPVMGRCVVLAGS-LNQPDGKTLPLLFAADAARELGASRVGLVAPYLA 89
Query: 94 YSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQ---IQGFFNIPVDNLYAEPA 150
Y RQD + + +T++ A L+S A D ++T+D H + + + I + A P
Sbjct: 90 YMRQDHRFNAGEAVTSRSYARLLS-ASLDFLVTVDPHLHRWRNLGDIYPIRTQAVAAAPM 148
Query: 151 ITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVGD 210
I +W++ ++ +++ PD + + +A D + ++ K R + T+ G
Sbjct: 149 IARWLRSHVDH---PLVIGPDQESGQWVAEVARLTDAPWTVLGKTRLGDRDVQVTLADGG 205
Query: 211 V-KNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAI 269
KT +++DD+ T T++ A AL +AG H +F A++++ ++ + +
Sbjct: 206 PWPGKTPVLLDDIISTGQTLVAAATALTQAGMAAPLCIGVHALFDSGALQRLQDAGVTRV 265
Query: 270 VVTNTIPQEKN-MKLCPKLQTIDISV 294
V +TI N ++L P L ++V
Sbjct: 266 VTCDTISHTSNAIRLAPLLARAVLAV 291
>UniRef50_Q1GQ93 Cluster: Ribose-phosphate pyrophosphokinase; n=6;
Bacteria|Rep: Ribose-phosphate pyrophosphokinase -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 299
Score = 88.6 bits (210), Expect = 2e-16
Identities = 66/264 (25%), Positives = 127/264 (48%), Gaps = 14/264 (5%)
Query: 23 LGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMINACKIASA 82
LG +GR T++F + ET + + V G D+ +V + + L+ L I +A + A
Sbjct: 23 LGGEVGRIETRRFPDGETYLRLLSEVAGRDIVLVCT-LDRPDTKLVSLLIAADAARELGA 81
Query: 83 SRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHA---SQIQGFFN 139
V V P Y RQD++ ++ I+++ A IS A D ++T D H + + ++
Sbjct: 82 FSVGLVAPYLAYMRQDRRFQNGEAISSRSFARRISGA-VDWLVTADPHLHRYASLGDIYD 140
Query: 140 IPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRA 199
I + ++A I+ WI+ ++ + +++ PD+ + + IA R A+ K R
Sbjct: 141 IRAEAVHAAAPISDWIRTHV---ERPLIIGPDSESEQWASAIARRAGAPHAVCSK--LRL 195
Query: 200 NEGDSTVLVGDVK---NKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGN 256
+ D + + D+ +T ++VDD+A + T+++ A + EAG + H +FA
Sbjct: 196 GDRDVRIALPDLSAHTGRTPVLVDDIASSARTLIEAARGIGEAGFPPPECVIVHPLFARG 255
Query: 257 AIEKINNSSLEAIVVTNTIPQEKN 280
A + ++ IV T+ + N
Sbjct: 256 AFAAL-SAEAGRIVSTDAVAHSSN 278
>UniRef50_Q607P3 Cluster: Ribose-phosphate pyrophosphokinase family
protein; n=2; Proteobacteria|Rep: Ribose-phosphate
pyrophosphokinase family protein - Methylococcus
capsulatus
Length = 289
Score = 87.4 bits (207), Expect = 4e-16
Identities = 69/288 (23%), Positives = 131/288 (45%), Gaps = 12/288 (4%)
Query: 16 AKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMIN 75
++ + LG +F + E+ V + VRG V V ND L+EL +
Sbjct: 10 SQELAGALGCPWRAIEVHRFPDGESRVRVPPDVRGTGV--VHRSLDRPNDKLVELVLAAE 67
Query: 76 ACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQ 135
+ R+ V P Y RQD ++ ++ K++ NL++ D +IT+D H +I
Sbjct: 68 TLRGQGCDRLVLVAPYLCYMRQDIAFQAGEAVSQKVVGNLLA-RYFDALITVDPHLHRID 126
Query: 136 GFFN-IPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHK 194
+P+ + + + T + + K +++ PD + + IA + + A+ K
Sbjct: 127 RLEQAVPLKRVLSVSSATLVSRYLATDRKEWLLLGPDQESRQWVEAIAAQAGLPCAVASK 186
Query: 195 ERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFA 254
R E ++ K ++VDD+A T T+ + A L AG +I +TH +F
Sbjct: 187 RRLGDREVGISLPQEAGAFKGVVLVDDIASTGTTLAETARLLARAGVARIDVIVTHALFT 246
Query: 255 GNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRR 302
G+A ++ + + AI T++I N ++C ++ +LA+A+R+
Sbjct: 247 GDAWSRLKQAGVGAIASTDSISHPTN-RMC-------LAPLLADAVRK 286
>UniRef50_Q4DSS9 Cluster: Ribose-phosphate pyrophosphokinase,
putative; n=3; Trypanosoma|Rep: Ribose-phosphate
pyrophosphokinase, putative - Trypanosoma cruzi
Length = 705
Score = 87.0 bits (206), Expect = 6e-16
Identities = 49/162 (30%), Positives = 92/162 (56%), Gaps = 18/162 (11%)
Query: 34 KFSNKETNVEIGESVRGEDVYIVQS--GCGEI----NDNLMELFIMINACKIASASRVTA 87
+F N E NV + ++RG+DV+++QS C + + MEL +M++ +++SA+R+TA
Sbjct: 302 QFPNGEINVSLSRTLRGDDVFVLQSLVRCDHLGLSHSGTFMELALMLHTARLSSAARITA 361
Query: 88 VVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFFNIPVDNLYA 147
V+P Y+ S + A+LL + G HVIT+D+ + Q++G F++P++N+ A
Sbjct: 362 VIPYLAYA----DSVSSVAVVAELLEKM----GCQHVITVDMSSEQVEGMFSVPLENISA 413
Query: 148 EPAITKWIKENIP----EWKSSVMVSPDAGGVKRMTGIADRL 185
++I +++ ++++ +VSP V R AD L
Sbjct: 414 RYEFVRFIAKHLTNEGHDFRNITVVSPSGTSVSRAKYFADAL 455
Score = 71.7 bits (168), Expect = 2e-11
Identities = 43/127 (33%), Positives = 66/127 (51%), Gaps = 3/127 (2%)
Query: 190 AIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLT 249
AI + D LVGDVK + I+VD D I + A L EAGA++I T
Sbjct: 577 AICEDRADNPAQTDGVALVGDVKGRLCIIVDTTIDEAIKICRTAWKLHEAGASRIILIAT 636
Query: 250 HGIFAGNAIEKINNSSLEAIVVTNTIPQE---KNMKLCPKLQTIDISVMLAEAIRRTHYA 306
H I + A E++ S ++ IVVT+++ Q+ K KL+ + I+ +LA AI + H
Sbjct: 637 HLILSAGAEERLVKSPIDLIVVTDSVNQDVVFKKPLFAQKLRLLPIAPLLARAIEKMHTE 696
Query: 307 ESVSYLF 313
+++ LF
Sbjct: 697 NTLATLF 703
>UniRef50_A6BI68 Cluster: Putative uncharacterized protein; n=2;
Clostridiales|Rep: Putative uncharacterized protein -
Dorea longicatena DSM 13814
Length = 395
Score = 86.6 bits (205), Expect = 7e-16
Identities = 80/318 (25%), Positives = 145/318 (45%), Gaps = 35/318 (11%)
Query: 30 ATTKKFSNKETNVEIGESVRGEDVYIVQSGC---------GEIN----DNLMELFIMINA 76
A +F + E I ESVRG+D+Y++ C G IN D+ + I A
Sbjct: 66 AKVPRFGSGEAKGIINESVRGKDLYLMVDVCNYNLTYSLTGNINHMSPDDHYQNLKRIIA 125
Query: 77 CKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQG 136
R+ ++P SRQ K+ + A L L+ + G D++IT D H ++Q
Sbjct: 126 AVGGKGRRINVIMPFLYESRQHKRSSRESLDCALALQELVRM-GVDNIITFDAHDPRVQN 184
Query: 137 FFNIPVDNLYAEPAITKWIKENIPEWKS-------SVMVSPDAGGVKRMTGIADRLDIDF 189
IP++ +++K + +K + +SPD G R +A+ L++D
Sbjct: 185 A--IPLNGFETIRPTYQFVKGLLRTFKDLQIDSDHMMAISPDEGATGRAIYLANVLNLDM 242
Query: 190 AIIHKERQ--RANEGDSTVLVGD-----VKNKTAIMVDDLADTCDTILKGAEALREAGAN 242
+ +K R R +G + ++ + V+ K I++DD+ + D++L A L++ A
Sbjct: 243 GMFYKRRDFSRVVDGRNPIVAHEFLGSSVEGKDVIILDDMISSGDSMLDVARQLKQRKAK 302
Query: 243 KIYAFLTHGIFAGNAIEKINNS----SLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAE 298
+I+ T G+F N +EK + + L+A++ TN I Q + P D+S +A
Sbjct: 303 RIFCAATFGLFT-NGLEKFDQAYEEGILDAVLTTNLIYQTPELLERPYYINCDMSKYIAL 361
Query: 299 AIRRTHYAESVSYLFTNV 316
I ++ S+S + +
Sbjct: 362 VIDTLNHDGSISSILNPI 379
>UniRef50_A1HDW3 Cluster: Ribose-phosphate diphosphokinase; n=3;
Ralstonia|Rep: Ribose-phosphate diphosphokinase -
Ralstonia pickettii 12J
Length = 313
Score = 86.2 bits (204), Expect = 1e-15
Identities = 69/261 (26%), Positives = 119/261 (45%), Gaps = 9/261 (3%)
Query: 23 LGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMINACKIASA 82
L LG A F + E+ V + V G +V IV + ++ L+ L + A + A
Sbjct: 31 LRAELGHAAVTHFPDGESYVRLYTPVHGAEVAIVCT-LDHPDEKLLPLLWLAIAARQGGA 89
Query: 83 SRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHA---SQIQGFFN 139
RV + P PY RQD + A+ A L++ D ++T+D H S++ +
Sbjct: 90 RRVGLIAPYLPYMRQDVIFNAGEIRAAEHFAALLNPV-FDWLVTVDPHLHRISRLSEVYR 148
Query: 140 IPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRA 199
+P + A PAI +WI+ ++ ++ ++ PD + + +A +A + K R A
Sbjct: 149 VPTVAVEAAPAIAEWIQTHV---QAPFLIGPDEESRQWVEQVAGMCGAPWAALTKTRHSA 205
Query: 200 NEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIE 259
+ T L ++VDD+ T T+L A L+ AG + H +FA +A
Sbjct: 206 WHVEVTELPNIPPRCVPVLVDDIISTGRTMLAAAGLLQRAGKPQPVCVGVHAVFAADAYS 265
Query: 260 KINNSSLEAIVVTNTIPQEKN 280
++ +S E +V +TIP N
Sbjct: 266 QLCAASAE-VVTCDTIPHPSN 285
>UniRef50_A2X0F3 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
Oryza sativa|Rep: Ribose-phosphate pyrophosphokinase -
Oryza sativa subsp. indica (Rice)
Length = 330
Score = 85.4 bits (202), Expect = 2e-15
Identities = 38/75 (50%), Positives = 55/75 (73%)
Query: 74 INACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQ 133
IN + ASA +TAV+P F Y+R D+K + R I AKL+AN+I+ AGA+ V+ DLH+SQ
Sbjct: 124 INIKRRASAKNITAVIPYFGYARADRKSQGRESIAAKLVANMITEAGANRVLVCDLHSSQ 183
Query: 134 IQGFFNIPVDNLYAE 148
G+F+IPVD++Y +
Sbjct: 184 AMGYFDIPVDHVYGQ 198
Score = 80.2 bits (189), Expect = 6e-14
Identities = 44/121 (36%), Positives = 71/121 (58%), Gaps = 17/121 (14%)
Query: 207 LVGDVKNKTAIMVDDLADTCD----------------TILKGAEALREAGANKIYAFLTH 250
L+GDV+ K A+M+DD+ DT D TI KGAE L + GA ++YA TH
Sbjct: 202 LIGDVRGKVAVMMDDMIDTADISLPNINILMKPIKLGTIAKGAELLHQEGAREVYACCTH 261
Query: 251 GIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRRTHYAESVS 310
+F+ AIE++++ + +++TNTIP +++ K P+L + ++ +L E I R H SV
Sbjct: 262 AVFSPPAIERLSSGLFQEVIITNTIPLKED-KSFPQLTILSVANLLGETIWRVHDDCSVG 320
Query: 311 Y 311
+
Sbjct: 321 H 321
>UniRef50_A4XET1 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Novosphingobium aromaticivorans DSM 12444|Rep:
Ribose-phosphate pyrophosphokinase - Novosphingobium
aromaticivorans (strain DSM 12444)
Length = 298
Score = 85.0 bits (201), Expect = 2e-15
Identities = 77/298 (25%), Positives = 136/298 (45%), Gaps = 27/298 (9%)
Query: 17 KTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMINA 76
+ + A LG+ +F + E+ V + R IV + N L+EL + A
Sbjct: 18 EALAAALGIPALPVEVHRFPDGESRVRLHPPAR---TAIVLRPLNDPNARLIELLLAAAA 74
Query: 77 CKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQG 136
+ A+RV V P Y RQD + ++ +++ NLI+ A D +IT+D H ++
Sbjct: 75 LRDGGAARVILVAPYLGYMRQDMAFRPGEAVSQRVIGNLIA-AHFDGLITVDPHLHRVSS 133
Query: 137 FFN----IPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAII 192
IP ++ A P + + + +V+V PD+ + IA L +D +
Sbjct: 134 LAEVAPGIPALSISAAPVLAAELAPGLDP--RTVLVGPDSESRPWVESIASPLGLDVLVG 191
Query: 193 HKERQRANEGDSTV---LVGD--VKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAF 247
K R GD V L G + + AI+VDD+ + T+++ A LR AGA + A
Sbjct: 192 EKVRH----GDRAVRIELPGKEALHGRPAILVDDVISSGTTLIECARILRAAGATSVEAV 247
Query: 248 LTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRRTHY 305
THG+ +++I + + + T++I +I ++ +LA+A+RR H+
Sbjct: 248 ATHGLARMQDLQRIAAAGVFRVRTTDSIAAHPG--------SIPLAPILAQALRRQHW 297
>UniRef50_O29666 Cluster: Ribose-phosphate pyrophosphokinase 1; n=2;
Archaeoglobus fulgidus|Rep: Ribose-phosphate
pyrophosphokinase 1 - Archaeoglobus fulgidus
Length = 284
Score = 85.0 bits (201), Expect = 2e-15
Identities = 65/273 (23%), Positives = 119/273 (43%), Gaps = 12/273 (4%)
Query: 6 VFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEIND 65
+ G ++ +A + GL L + ++ + E ++ GEDV I S ++
Sbjct: 3 ILVGGTNGLMALKVAKISGLPLCYSHVDRYPDGEKYFRFASNIDGEDVVIFNSMHPNPDE 62
Query: 66 NLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVI 125
+ E ++ A VT V P F Y+R K A + K + ++ AG +I
Sbjct: 63 IIFETLLIAETAYSNGARSVTCVFPYFAYARSLDTVKGEA-LPIKTVVKVLKAAGVKKII 121
Query: 126 TIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRL 185
T+D H + F + +L + ++ E + S +++PD A +
Sbjct: 122 TVDFHLQE--NVFGVEHVDLTGMEKLAEYCLEEFSD--SFTVLAPDEKAAFWAEKFAAKA 177
Query: 186 DIDFAIIHKERQRANEGDSTVLVGDVKNKT---AIMVDDLADTCDTILKGAEALREAGAN 242
+ D + K R A V++ D++ ++VDD+ T T+ + A + AGA
Sbjct: 178 NCDVVALRKIRIDAEN----VIIDDLRTGVEGDVVIVDDIVSTGGTVCQAARIAKRAGAR 233
Query: 243 KIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTI 275
+++ TH I A +A+ +I S +E IV T+TI
Sbjct: 234 RVFVACTHAILARDAMMRILESGIEDIVSTDTI 266
>UniRef50_Q97KU7 Cluster: Phosphoribosylpyrophosphate synthetase;
n=5; Clostridium|Rep: Phosphoribosylpyrophosphate
synthetase - Clostridium acetobutylicum
Length = 371
Score = 84.6 bits (200), Expect = 3e-15
Identities = 78/307 (25%), Positives = 146/307 (47%), Gaps = 33/307 (10%)
Query: 34 KFSNKETNVEIGESVRGEDVYIV----QSGC-----GEIN-----DNLMELFIMINACKI 79
+FSN E V++ ESVRG+D+YI+ C G N ++ ++ ++A +
Sbjct: 50 RFSNGEGKVKLSESVRGKDIYILCDVGNYSCTYNMFGIENHKGPDEHFQDIKRTVSAIR- 108
Query: 80 ASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFFN 139
A R+T ++P SRQ ++ K R + L + G V+T D H +Q
Sbjct: 109 GKARRITVIMPLLYESRQHRR-KGRESLDCALALQELERLGVQEVLTFDAHDPNVQNAIP 167
Query: 140 I-PVDNLYAEPAITKWI---KENIPEWKSSVMV-SPDAGGVKRMTGIADRLDIDFAIIHK 194
+ +NLY I K I ++NI K+S++V SPD G + R + L +D + +K
Sbjct: 168 LMSFENLYPTYDIVKTIIMEEKNIEVNKNSMLVISPDTGAMDRAIYYSSVLGVDVGLFYK 227
Query: 195 ERQRAN--EGDSTVL----VG-DVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAF 247
R + G + ++ +G DV+N+ ++VDD+ + +++L A+ L+ A IY
Sbjct: 228 RRDHSTIVNGKNPIVKHEYMGRDVENQDVLIVDDMIASGESVLDIAKELKARKARNIYVA 287
Query: 248 LTHGIFAGNAIEKI----NNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRRT 303
T F +EK +++ + + TN ++ + +D+S +++ I +
Sbjct: 288 TTFAFFT-EGLEKFQKYYDDNIISRVYSTNLTYIPPELEKTEWFRKVDMSELISRIIHKL 346
Query: 304 HYAESVS 310
+ ES++
Sbjct: 347 NKDESIA 353
>UniRef50_Q1FFM9 Cluster: Ribose-phosphate pyrophosphokinase; n=8;
Clostridiales|Rep: Ribose-phosphate pyrophosphokinase -
Clostridium phytofermentans ISDg
Length = 390
Score = 84.2 bits (199), Expect = 4e-15
Identities = 72/307 (23%), Positives = 142/307 (46%), Gaps = 32/307 (10%)
Query: 34 KFSNKETNVEIGESVRGEDVYIVQSGCGEIN--------------DNLMELFIMINACKI 79
+F E I E++RG D++++ N D+ +L +I A KI
Sbjct: 67 RFGTGEAKAVINETIRGCDLFLIADVTNYTNHYMMFGEDSMKSPDDHFQDLKRVIAAAKI 126
Query: 80 ASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFFN 139
+ RV ++P RQ ++K + A L L S G +++IT D H +IQ
Sbjct: 127 SKVKRVNVILPFLYEGRQHHRDKLESLDCANALQEL-SEMGVENIITFDAHDPRIQNAIP 185
Query: 140 IP-VDNLYAEPAITK---WIKENIPEWKSSVMV-SPDAGGVKRMTGIADRLDIDFAIIHK 194
I DN Y + +I++++ K +MV SPD GG+ R A+ L ++ + +K
Sbjct: 186 IRGFDNFYTSLQFIRELLFIEKDLVIDKDHLMVISPDEGGMTRAVYYANVLGVEMGMFYK 245
Query: 195 ERQRAN--EGDSTVLVGD-----VKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAF 247
R + +G + ++ + ++ K +VDD+ + D+I+ A+ L+ A +++
Sbjct: 246 RRDYSTIIDGRNPIVAHEFLGSSLEGKDVFIVDDIISSGDSIIDVAKELKRRKAGRVFIA 305
Query: 248 LTHGIFAGNAIEKINN----SSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRRT 303
T G+F N +E+++ ++ I TN + + + P + +D+S ++ +
Sbjct: 306 ATFGLFC-NGLERVDEYYEAGYIDRIYTTNLVYNNEELLKRPYYRNVDLSRYISLIVDTL 364
Query: 304 HYAESVS 310
++ SV+
Sbjct: 365 NHDTSVN 371
>UniRef50_Q4QIB8 Cluster: Ribose-phosphate pyrophosphokinase,
putative; n=3; Leishmania|Rep: Ribose-phosphate
pyrophosphokinase, putative - Leishmania major
Length = 836
Score = 83.8 bits (198), Expect = 5e-15
Identities = 50/162 (30%), Positives = 94/162 (58%), Gaps = 18/162 (11%)
Query: 34 KFSNKETNVEIGESVRGEDVYIVQSGCGEINDNL------MELFIMINACKIASASRVTA 87
+F+N E +V + VRG+DV++VQS ++NL MEL +++++ ++A+A+R+TA
Sbjct: 368 RFANGEVSVNLQAPVRGDDVFVVQSMVALESENLSNAGALMELALLVHSAQLAAAARITA 427
Query: 88 VVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFFNIPVDNLYA 147
V+P Y+ + A I+A +A +I + G HVIT+D+H+ Q++G F+IP+++ A
Sbjct: 428 VIPYLAYT------SNVASISA--VAEMIELVGCHHVITVDMHSDQVEGMFSIPIESASA 479
Query: 148 EPAITKWIKENIPE----WKSSVMVSPDAGGVKRMTGIADRL 185
++I + +++ +V+P + R AD L
Sbjct: 480 MYEFVRYISNLLESEGNTFENITVVAPSGEFLGRAKEYADAL 521
Score = 81.0 bits (191), Expect = 4e-14
Identities = 43/127 (33%), Positives = 73/127 (57%), Gaps = 3/127 (2%)
Query: 190 AIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLT 249
A+I ++ +NE VLVGDVK++ I+++ + D I A L+E GA +I T
Sbjct: 707 ALIMRKETASNEYKKYVLVGDVKDRLCIIIESVIDEAINITNVARCLQEHGAERIILVAT 766
Query: 250 HGIFAGNAIEKINNSSLEAIVVTNTIPQE---KNMKLCPKLQTIDISVMLAEAIRRTHYA 306
H + +G AI + S +E ++VT+++ Q+ KN L KL+ + I+ +LA AI + H
Sbjct: 767 HAVMSGKAIHLLVESPIELVLVTDSVNQDELMKNPALARKLRVVPIAPLLARAIEKIHTE 826
Query: 307 ESVSYLF 313
+++ LF
Sbjct: 827 NTLATLF 833
>UniRef50_Q6KG64 Cluster: Putative uncharacterized protein; n=2;
Enterobacteria phage Felix 01|Rep: Putative
uncharacterized protein - Enterobacteria phage Felix 01
Length = 298
Score = 81.0 bits (191), Expect = 4e-14
Identities = 52/201 (25%), Positives = 103/201 (51%), Gaps = 9/201 (4%)
Query: 86 TAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFFNIPVDNL 145
T V P +R D+ K+ ANL++ G D V +D H++ + F ++
Sbjct: 92 TVVFGFLPNARYDRHMFKGDAAALKVFANLVNAMGFDAVCALDPHSNVAENLFKC-FQSM 150
Query: 146 YAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQ-RANEGDS 204
+ + + + ++ +V+PDAG K++ A +D + + K R + E
Sbjct: 151 KQKDVAVHYANDPLIDY----LVAPDAGASKKIAETAKEVDKPYITMSKVRNLKTGEITG 206
Query: 205 TVLVGDVK--NKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKIN 262
++ DV +KT +++DD+ D T ++ A+ LREAGA ++ ++THGIF+ + +E +
Sbjct: 207 MRILDDVDLTDKTVMILDDICDGGRTFVEAAKHLREAGAKRVELYVTHGIFSKD-VENLL 265
Query: 263 NSSLEAIVVTNTIPQEKNMKL 283
++ ++ I TN++ + K+ L
Sbjct: 266 DNGIDHIYTTNSLGEAKDRGL 286
>UniRef50_A3W7X1 Cluster: Phosphoribosylpyrophosphate synthetase;
n=2; Roseovarius|Rep: Phosphoribosylpyrophosphate
synthetase - Roseovarius sp. 217
Length = 315
Score = 79.8 bits (188), Expect = 9e-14
Identities = 61/270 (22%), Positives = 120/270 (44%), Gaps = 9/270 (3%)
Query: 15 IAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMI 74
+A+ + LG +L F + E+ + + + G DV + + + + + L
Sbjct: 12 LAEDLAPALGADLLTLDWHHFPDGESLISLPGDLDGADVAFLAT-LRDPDRLALPLRFAA 70
Query: 75 NACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQI 134
+ A RV + P Y RQD++ + ++A L A + + D ++++D H +I
Sbjct: 71 ATAREMGARRVGLIAPYLGYMRQDRRFERGQAVSAPLFAQFLGES-FDWLVSVDPHLHRI 129
Query: 135 ---QGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAI 191
Q F +P + P + WI N+P+ +V++ PD+ + + +A + +
Sbjct: 130 ARLQDVFPMPAIRAVSAPLLATWISTNLPD---AVLLGPDSESQQWVAEVARLAGRPYEV 186
Query: 192 IHKERQRANEGDSTVLVGD-VKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTH 250
+ K R D +V ++ T +++DD+A + T+ + E L AG H
Sbjct: 187 LRKVRSGDRSVDVSVPESAALREGTPVILDDIASSGVTMARAVERLLAAGTAAPVCLAIH 246
Query: 251 GIFAGNAIEKINNSSLEAIVVTNTIPQEKN 280
+FA A + I ++ I+ T+TIP N
Sbjct: 247 AVFAHGAQDAILSAGAARIITTDTIPHPTN 276
>UniRef50_Q21W91 Cluster: Ribose-phosphate pyrophosphokinase; n=2;
Proteobacteria|Rep: Ribose-phosphate pyrophosphokinase -
Rhodoferax ferrireducens (strain DSM 15236 / ATCC
BAA-621 / T118)
Length = 301
Score = 77.8 bits (183), Expect = 3e-13
Identities = 64/270 (23%), Positives = 119/270 (44%), Gaps = 12/270 (4%)
Query: 16 AKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMIN 75
A I G +L R +F + E + + ++ D ++ + N+ L+EL +
Sbjct: 17 AARIAQVAGHHLVRIDRHRFPDGELKLRLPPTL--PDHVVILRTLNDPNEKLVELLLTAQ 74
Query: 76 ACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGA-DHVITIDLHASQI 134
+ A +T V P Y RQD + I+ +++ + AG D VIT+D H ++
Sbjct: 75 TARDLGARHLTLVAPYLGYMRQDVAFQPGEAISQRIVGRFL--AGLFDAVITVDPHLHRV 132
Query: 135 QGFFN-IPVDN---LYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFA 190
+PV N L A P ++ I P+ ++++ PD + + A R D+A
Sbjct: 133 ATLQQAVPVANAVVLSAAPLLSDLIVTQRPK---ALLLGPDEESAQWLALAASRHGFDYA 189
Query: 191 IIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTH 250
+ K R+ D + V + +++DD+ T T+ + L AGA + +TH
Sbjct: 190 VCRKVRRGDRAVDIALPDILVSGRQVVLLDDVVSTGHTLAQATRQLLAAGAASVDVAVTH 249
Query: 251 GIFAGNAIEKINNSSLEAIVVTNTIPQEKN 280
+F G+A + I N+ + + T+ + N
Sbjct: 250 ALFVGDAWQMILNAGVREVWSTDCVKHASN 279
>UniRef50_A7B5K6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus gnavus ATCC 29149|Rep: Putative
uncharacterized protein - Ruminococcus gnavus ATCC 29149
Length = 420
Score = 76.2 bits (179), Expect = 1e-12
Identities = 66/269 (24%), Positives = 121/269 (44%), Gaps = 31/269 (11%)
Query: 34 KFSNKETNVEIGESVRGEDVYIVQSGC---------GEIN----DNLMELFIMINACKIA 80
+F + E I E++RG D++I+ C G +N D+ + + A
Sbjct: 98 RFGSGEAKGVIKETIRGTDLFIMSDVCNYSLTYSVNGHLNHMSPDDHFQDIKRVIAASTG 157
Query: 81 SASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFFNI 140
A RV ++P SRQ K+ K R + L + G +++T D H ++Q +
Sbjct: 158 KAHRVNVIMPFLYESRQHKRTK-RESLDCALALEELKDMGVANILTFDAHDPRVQNAIPL 216
Query: 141 P-VDNLYAEPAITKWIKENIPEWKSS----VMVSPDAGGVKRMTGIADRLDIDFAIIHKE 195
DN + K + +P+ K S ++VSPD G + R ++ L +D + +K
Sbjct: 217 SGFDNFTPQYQFMKALFRAVPDLKVSKDHLMIVSPDEGAMHRAVYFSNVLGVDMGMFYKR 276
Query: 196 RQRAN--EGDSTVLV-----GDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFL 248
R + G + ++ DV K I+VDD+ + +++L A+ L++ A +++
Sbjct: 277 RDYSTIVNGKNPIVAHEFLGDDVAGKDVIIVDDMISSGESMLDVAKKLKDRNAARVFVCT 336
Query: 249 THGIFAGNAIEKIN----NSSLEAIVVTN 273
T G+F + EK + L+ +V TN
Sbjct: 337 TFGLFT-DGFEKFDEYYKKGYLDKVVTTN 364
>UniRef50_A6DTG6 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Ribose-phosphate
pyrophosphokinase - Lentisphaera araneosa HTCC2155
Length = 390
Score = 74.5 bits (175), Expect = 3e-12
Identities = 76/278 (27%), Positives = 127/278 (45%), Gaps = 35/278 (12%)
Query: 34 KFSNKETNVE-IGESVRGEDVYIV--QSGCGEINDNLMELFIMINACKIASASRVTAVVP 90
+F N ET E IG ++G+ V IV QS N M ++ A K A +V + P
Sbjct: 46 RFINDETAFEDIGYYLKGKTVVIVSTQSLTFSRNSLSMRNLVIARAAKDNGAEQVILMEP 105
Query: 91 CFPYSRQDK----------KEKSRA--------PITAKLLANLISVAGADHVITIDLHAS 132
YS QD+ +E+S P TA L A L+S+AG D TI H+
Sbjct: 106 DLFYSCQDRGPRHEHSFFNEERSAEIRKKFDGQPFTALLYAQLLSLAGVDQAFTIHNHSF 165
Query: 133 QIQGFFNIPVDNLYAE----PAITKWIKEN-IPEWKSSVMVSPDAGGVKRMTGIADRLD- 186
Q F ++ + + ++ + I + +++ +PD G V + I D +
Sbjct: 166 STQNLFQKELNGYFHNYVPCDIFSHYLASSGIVDPGKTILCAPDKGAVPFVQMIKDEMSH 225
Query: 187 IDFAIIHKERQRANEG--------DSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALRE 238
++ I+ ++ R+ E DS + + D++ K I+ DD+ T TI+K L++
Sbjct: 226 LNPPILKMDKVRSGERAIEMEPSEDSDIGMEDIEGKDVIVFDDMVRTGTTIVKCCRILKQ 285
Query: 239 AGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIP 276
+I +TH + + EK+ + S++ IV TNTIP
Sbjct: 286 YKPRRIIFCVTHFHSSAESREKLADHSIDEIVTTNTIP 323
>UniRef50_A4FCC2 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
Ribose-phosphate pyrophosphokinase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 165
Score = 72.1 bits (169), Expect = 2e-11
Identities = 49/148 (33%), Positives = 75/148 (50%), Gaps = 3/148 (2%)
Query: 166 VMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADT 225
V+V+PD G VK A L A++ K RQ + + LVGDV++K ++VDD+ T
Sbjct: 16 VVVAPDLGAVKLAEHCAAPLRAPVAVVRKTRQTGSTVRAEELVGDVESKPVLIVDDMIST 75
Query: 226 CDTILKGAEALREAGA-NKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNMKLC 284
TI A L E GA + I HG+ A +++ L ++ VT+++ Q +
Sbjct: 76 GGTIEAAAHVLLEHGALSGITVVAAHGLLVDPAADRLAALPLRSLFVTDSLAQRASAAF- 134
Query: 285 PKLQTIDISVMLAEAIRRTHYAESVSYL 312
L+ I+ +LA+AI R H SV L
Sbjct: 135 -PLEVHSIAPLLADAIGRLHQNLSVDDL 161
>UniRef50_Q7XZ65 Cluster: Phosphoribosyl pyrophosphate synthetase;
n=1; Griffithsia japonica|Rep: Phosphoribosyl
pyrophosphate synthetase - Griffithsia japonica (Red
alga)
Length = 92
Score = 71.7 bits (168), Expect = 2e-11
Identities = 37/90 (41%), Positives = 54/90 (60%), Gaps = 1/90 (1%)
Query: 227 DTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKNM-KLCP 285
+ + K A AL E GA + A H + +G A+++IN S ++ +V+TN+I + M K P
Sbjct: 2 EALTKAAVALSENGAKSVRACCIHAVLSGPAVDRINASCIKELVITNSIAHSEEMRKKLP 61
Query: 286 KLQTIDISVMLAEAIRRTHYAESVSYLFTN 315
L T+ I ++AE IRR H ESVS LF N
Sbjct: 62 CLTTLSIGNVMAETIRRVHREESVSTLFDN 91
>UniRef50_UPI00004989B9 Cluster: ribose-phosphate pyrophosphokinase;
n=2; Entamoeba histolytica HM-1:IMSS|Rep:
ribose-phosphate pyrophosphokinase - Entamoeba
histolytica HM-1:IMSS
Length = 337
Score = 71.3 bits (167), Expect = 3e-11
Identities = 68/286 (23%), Positives = 132/286 (46%), Gaps = 23/286 (8%)
Query: 33 KKFSNKET----NVEIGESVRGEDVYIVQSGCGEINDN-LMELFIM-INACKIASASRVT 86
K+FS+ E ++ S+ G+DV IV C ++D L+EL + + ++ + RV
Sbjct: 37 KQFSDGELYYKFTIQNKTSLIGKDVLIV---CSMVDDQELLELIRLGLELSELGTRRRVF 93
Query: 87 AVVPCFPYSRQDKKEKSRAPITAKLLANL---ISVAGADHV-ITIDLHASQIQGFFN-IP 141
V+P Y ++ +T K + IS G ++ + +DLH S I +F
Sbjct: 94 -VIPYLLYQTMNRASLPGEVVTCKSTVRMLSSISTCGLGNLYLLLDLHTSGIIHYFEKTQ 152
Query: 142 VDNLYAEPAITKWIKENIPEWKSSVMV-SPDAGGVKRMTGIADRLDIDFAIIHKERQRAN 200
LYA+ + I + + V+ + D G K + ++ + + R+ N
Sbjct: 153 AMELYAQKPLYNAIAKEVDFQNEDVVFGTTDLGRPKWVETYSNLFGVGIVLCRAPRE-LN 211
Query: 201 EGDSTVL---VGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTH-GIFAGN 256
E ++ +G+ K K ++ DD+ + T + AE GA K+ ++H + +
Sbjct: 212 ENSPEIMKEPIGECKGKHVVLYDDIIRSGKTAIAAAENYLRHGATKVTCVISHFAVTKES 271
Query: 257 AIEKINNSSLEAIVVTNT--IPQEKNMKLCPKLQTIDISVMLAEAI 300
I+++ S ++ I++TN+ Q +KLC K++ +D+S + E I
Sbjct: 272 IIQRLEQSPIDKIIITNSHINSQLLAVKLCKKIRIVDVSCVFVEQI 317
>UniRef50_Q11SD6 Cluster: Phosphoribosylpyrophosphate synthetase;
n=2; Bacteroidetes|Rep: Phosphoribosylpyrophosphate
synthetase - Cytophaga hutchinsonii (strain ATCC 33406 /
NCIMB 9469)
Length = 289
Score = 70.1 bits (164), Expect = 7e-11
Identities = 60/250 (24%), Positives = 109/250 (43%), Gaps = 12/250 (4%)
Query: 35 FSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMINACKIASASRVTAVVPCFPY 94
FS E +++I V V ND + L + ++A + ++ +P FP
Sbjct: 34 FSGGEPHIKIRPDVDTNQPITVTHRLNSFNDVGL-LLVAVDALRRMHVDKINLFIPYFPA 92
Query: 95 SRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFFNIPVDNLYAEPAITKW 154
+RQD+ P+T K+ A LI+ V D H+ N N A + ++
Sbjct: 93 ARQDRVMVKGEPLTVKVYAELINALQLSKVTVFDAHSEVTPALLN----NCEA-VSNHRF 147
Query: 155 IKENIP-EWKSSVMVSPDAGGVKRMTGIADRL-DIDFAIIHKERQ--RANEGDSTVLVGD 210
I++ + +++SPD G +K++ +++ L I K R V D
Sbjct: 148 IQQVLKITGNDCLLISPDGGALKKIYKVSEYLGGIQVVECSKSRDVTTGKLKGFKVYADD 207
Query: 211 VKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIV 270
++ K ++VDD+ D T + AE L++ IY ++HGIF+ EK + + + I
Sbjct: 208 LQGKDCLIVDDICDGGGTFIGLAEELKKKNCGAIYLAVSHGIFS-QGFEKF-SPAFKRIF 265
Query: 271 VTNTIPQEKN 280
T++ +N
Sbjct: 266 TTDSFQNIEN 275
>UniRef50_Q93Z66 Cluster: Ribose-phosphate pyrophosphokinase 3; n=9;
Magnoliophyta|Rep: Ribose-phosphate pyrophosphokinase 3
- Arabidopsis thaliana (Mouse-ear cress)
Length = 411
Score = 68.1 bits (159), Expect = 3e-10
Identities = 65/257 (25%), Positives = 115/257 (44%), Gaps = 14/257 (5%)
Query: 6 VFTGSSHPDIAKTIVARLG-LNLGRATTKKFSNKETNVEI--GESVRGEDVYIVQSGCGE 62
+F D+A+ IVA+ + L KKF + N+ I + +RG+ V + S
Sbjct: 103 LFHSDETRDLAERIVAKSDCIELRSINWKKFDDGFPNLFIQNAQGIRGQHVAFLASFSSP 162
Query: 63 INDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISV---- 118
+ E +I A S T V+P FP ++ E TA LA ++S
Sbjct: 163 AV--IFEQLSVIYALPKLFVSSFTLVLPFFPTGTSERMEDEGDVATAFTLARILSNIPTS 220
Query: 119 -AGADHVITIDLHASQIQGFFNIPVDNLYAEPA-ITKWIKENIPEWKSSVMVSPDAGGVK 176
G ++T D+HA Q + +F + + + K +++P+ + + PD G K
Sbjct: 221 RGGPTSLVTFDIHALQERFYFGDTILPCFESGIPLLKSRLQSLPDSDNISIAFPDDGAWK 280
Query: 177 RMTGIADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEAL 236
R +L I+ + + ++ + GD + + ++VDDL + T+++ + L
Sbjct: 281 RFH---KQLQHYPTIVCNKVRMGDKRIVRIKEGDAEGRHVVIVDDLVQSGGTLIECQKVL 337
Query: 237 REAGANKIYAFLTHGIF 253
GA KI A++THGIF
Sbjct: 338 AAHGAAKISAYVTHGIF 354
>UniRef50_Q6FDK1 Cluster: Putative ribose-phosphate
pyrophosphokinase; n=2; Acinetobacter|Rep: Putative
ribose-phosphate pyrophosphokinase - Acinetobacter sp.
(strain ADP1)
Length = 293
Score = 66.1 bits (154), Expect = 1e-09
Identities = 61/245 (24%), Positives = 113/245 (46%), Gaps = 33/245 (13%)
Query: 64 NDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADH 123
+D++++ ++ N I + +P FPY+RQD+ + + + +L+++ H
Sbjct: 49 SDDILDYLLLENVL-IQHRKNIEVEIPYFPYARQDRVCATGQAFSLDVFCHLLNINIEKH 107
Query: 124 V-----ITI-DLHASQIQGFFN-----------IPVDNLYAEPAITKWIKENIPEWKSSV 166
IT+ D H++ I N PV+ + PA+T+ +++ + +V
Sbjct: 108 TSIRRRITLWDAHSNVIGQLLNGYSSHLDLYQVEPVEIIKTSPALTELLQQ-----QHTV 162
Query: 167 MVSPDAGGVKRMTGIAD----RLDIDFAIIHKERQRA-NEG---DSTVLVGDVKNKTAIM 218
+V PD G R IA + AIIH ++ R G S V G + KTA++
Sbjct: 163 LVCPDRGAKARTAAIAQYFNPKRSQQIAIIHCDKTREPTTGKITSSVVKTGSLAGKTAVI 222
Query: 219 VDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQE 278
DD+ D T + A+ LR+ I ++THGIF+ + + ++ I +N+ PQ+
Sbjct: 223 TDDICDGGATFIGIAKELRKLQCEHIILYVTHGIFSRGL--DVFDGLIDQIFTSNSRPQQ 280
Query: 279 KNMKL 283
+ L
Sbjct: 281 FHKNL 285
>UniRef50_Q8KTQ3 Cluster: Phosphoribosylpyrophosphate synthetase;
n=4; Candidatus Tremblaya princeps|Rep:
Phosphoribosylpyrophosphate synthetase - Tremblaya
princeps
Length = 199
Score = 65.7 bits (153), Expect = 1e-09
Identities = 47/168 (27%), Positives = 87/168 (51%), Gaps = 17/168 (10%)
Query: 9 GSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLM 68
G+ +A+ I G+ +G ++++ E +I ++VR D ++ + C +N
Sbjct: 8 GTGTIGLARRISRHCGIRVGLMECGRYADGERYGDIAQNVRNNDELLLHTLCSPVNS--- 64
Query: 69 ELFIMINACKIASASRVTAVVPCFPYSRQDKKEK-SRAPITAKLLANLISVAGADHVITI 127
I +A AS VT V+P Y RQ+K + +RA ++A+ +A+++S +++ +
Sbjct: 65 -----IGEIILAQASGVTLVLPYVAYGRQEKHAQGTRATLSARCVASVLS----RNLVAM 115
Query: 128 DLHASQIQGFFNIPVDNLYAEPAITKWIKENIP-EWKSSVMVSPDAGG 174
DLH S+ FF++P L A ++ +P +S+ VSPDAGG
Sbjct: 116 DLHLSKRHVFFDVPTQLLSMRHAFDEY---RLPGSARSTARVSPDAGG 160
>UniRef50_Q680A5 Cluster: Ribose-phosphate pyrophosphokinase 4;
n=13; Viridiplantae|Rep: Ribose-phosphate
pyrophosphokinase 4 - Arabidopsis thaliana (Mouse-ear
cress)
Length = 337
Score = 64.9 bits (151), Expect = 3e-09
Identities = 61/261 (23%), Positives = 123/261 (47%), Gaps = 18/261 (6%)
Query: 14 DIAKTIVARLG-LNLGRATTKKFSNKETNVEIGES--VRGEDV-YIVQSGCGEINDNLME 69
++A+ I A + L + F++ N+ I + +RG+ V ++ + +
Sbjct: 38 ELARNIAAESDHITLQSINWRSFADGFPNLFINNAHDIRGQHVAFLASFSSPAVIFEQIS 97
Query: 70 LFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPIT-AKLLANL-ISVAGADHVITI 127
+ ++ +AS + V P + R +++ T A++++N+ IS G V+
Sbjct: 98 VIYLLPRLFVASFTLVLPFFPTGSFERMEEEGDVATAFTMARIVSNIPISRGGPTSVVIY 157
Query: 128 DLHASQIQGFFNIPVDNLYAE--PAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRL 185
D+HA Q + +F V L+ P +TK +++ +PE + ++ PD G KR + D
Sbjct: 158 DIHALQERFYFADQVLPLFETGIPLLTKRLQQ-LPETEKVIVAFPDDGAWKRFHKLLDHY 216
Query: 186 DIDFAIIHKERQRANEGDSTVL---VGDVKNKTAIMVDDLADTCDTILKGAEALREAGAN 242
+ K R EGD ++ G+ ++VDDL + T+++ + L GA
Sbjct: 217 PT--VVCTKVR----EGDKRIVRLKEGNPAGCHVVIVDDLVQSGGTLIECQKVLAAHGAV 270
Query: 243 KIYAFLTHGIFAGNAIEKINN 263
K+ A++THG+F ++ E+ +
Sbjct: 271 KVSAYVTHGVFPKSSWERFTH 291
>UniRef50_A6VUG9 Cluster: Ribose-phosphate pyrophosphokinase; n=4;
Gammaproteobacteria|Rep: Ribose-phosphate
pyrophosphokinase - Marinomonas sp. MWYL1
Length = 403
Score = 63.7 bits (148), Expect = 6e-09
Identities = 75/332 (22%), Positives = 139/332 (41%), Gaps = 45/332 (13%)
Query: 12 HPDIAKTIVARLGLNLGRATTKKFSNKETNVE-IGESVRGEDVYIVQSGCG--EINDNLM 68
H DIA I + +N +F + E + + IG ++G+ V IV +G + M
Sbjct: 33 HEDIADLISMKQFMN--SEFCPRFISDEADFDNIGRKLKGKSVIIVSTGSHVKSRQELAM 90
Query: 69 ELFIMINACKIASASRVTAVVPCFPYSRQDK------------------KEKSRAPITAK 110
I+ A K A RV V P YS QD+ K+ P TAK
Sbjct: 91 ANLIIARAAKENGADRVILVEPDLFYSAQDRGPHQSLGETSFERDIQDVKKFDGQPFTAK 150
Query: 111 LLANLISVAGADHVITIDLHASQIQ---------GFFNIPVDNLYAEPAITKWIKENIPE 161
L A L+ ++G D V+TI H+ +Q F N+ +YA + I +
Sbjct: 151 LYAQLLKLSGVDTVMTIHNHSDSVQKMFTEVFEGDFHNLIPYEIYAHYLLNSNILNYGED 210
Query: 162 WKSSVMVSPDAGG---VKRMTGIADRLDIDFAIIHKERQRANEGDSTV------LVGDVK 212
+ V+ +PD G VK M F ++ K+R + + T+ +
Sbjct: 211 GEGLVLCAPDKGARDFVKEMFKTLGLSKAKFIMLDKDRTAERKVEITLHKESEHTFDGLD 270
Query: 213 NKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVT 272
+ ++ DD+ T T++K + L++ ++ ++H + E++ + ++ I+
Sbjct: 271 GASIVLFDDMVRTGSTVVKSCQFLQQINPERMVFAVSHFYASDEGRERMAHPAIGEILTL 330
Query: 273 NTIP----QEKNMKLCPKLQTIDISVMLAEAI 300
NT+P +++ +L K+ + + LA+ +
Sbjct: 331 NTLPTILNRDEQGRLRKKMVVLKVEKWLAQEL 362
>UniRef50_A2FHP9 Cluster: Ribose-phosphate pyrophosphokinase family
protein; n=1; Trichomonas vaginalis G3|Rep:
Ribose-phosphate pyrophosphokinase family protein -
Trichomonas vaginalis G3
Length = 333
Score = 63.3 bits (147), Expect = 8e-09
Identities = 51/223 (22%), Positives = 97/223 (43%), Gaps = 11/223 (4%)
Query: 88 VVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADH----VITIDLHASQIQGFFN---I 140
V+P YS D+ + +K+ L S GA + +DLH + + +F +
Sbjct: 98 VIPFLAYSSNDRAISPGEVVVSKINHTLFSSLGATDEGNVFVFLDLHTAGLLHYFEGSCL 157
Query: 141 PVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRAN 200
++ LY + A+ I + V+ +P+ K + A + A + +
Sbjct: 158 RIE-LYGQRALCDAIYSAGFDMSKVVIGAPNLRDSKWVNSYASEFKVPIAFVTQNSTLEE 216
Query: 201 EGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTH-GIFAGNAIE 259
++++GDV+ K I+ DL + ++ + AGA+ + L+H I N I+
Sbjct: 217 NSPGSLVIGDVQGKHVIVYSDLIRSSSAVINVTKTYLNAGASSVDFMLSHFAIVDENQIK 276
Query: 260 KINNSSLEAIVVTNTIP--QEKNMKLCPKLQTIDISVMLAEAI 300
+I +S + I TN+ P Q + ++ PK IDI+ A +
Sbjct: 277 EIADSPVSGIYATNSHPITQTELVRSSPKFHIIDIAPYFARCL 319
>UniRef50_A6LV64 Cluster: Ribose-phosphate pyrophosphokinase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
Ribose-phosphate pyrophosphokinase - Clostridium
beijerinckii NCIMB 8052
Length = 266
Score = 61.3 bits (142), Expect = 3e-08
Identities = 74/267 (27%), Positives = 119/267 (44%), Gaps = 18/267 (6%)
Query: 25 LNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEINDNLMELFIMINACKIASASR 84
LN KKF N E+ + E E V ++ ND +F+ + ++ +
Sbjct: 4 LNDKEIEVKKFPNGESLINSQELNIKEWVNTIKLKFESDNDITHLIFLKDHLDELNI--K 61
Query: 85 VTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFFN-IPVD 143
++P PYSR D+ E T K L LI+ + V + H+ + + V
Sbjct: 62 CNLIIPYMPYSRMDRTEGFTV-FTLKHLCRLINNLNFEEVSIYEPHSDVCVALLDRVKVI 120
Query: 144 NLYAEPAITKWIKENIPEWKSSV-MVSPDAGGVKRMTGIADRLDIDFAIIHKERQ-RANE 201
N+ A + K + E + + K SV +V PDAG KR I A +KER +
Sbjct: 121 NMSA--ILAKNLLEKVDDKKDSVYLVYPDAGAAKRYGKQIQYEKILTA--NKERDFKTGF 176
Query: 202 GDSTVLVGDVKNKT--AIMVDDLADTCDTILKGAEALREAGANKIYAFLTH---GIFAGN 256
+ + G V++K AI+VDDL T + A+ L+E GA +IY +TH IF G
Sbjct: 177 INKLEINGTVESKKFKAIIVDDLCSKGGTFILTAKKLKEMGATEIYLVVTHCEDTIFDG- 235
Query: 257 AIEKINNSSLEAIVVTNTIPQEKNMKL 283
E + + + T++I +++ KL
Sbjct: 236 --EILKTDLITKVFTTSSILSKEHEKL 260
>UniRef50_Q0U4M2 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 89
Score = 61.3 bits (142), Expect = 3e-08
Identities = 30/54 (55%), Positives = 36/54 (66%)
Query: 6 VFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSG 59
VF GSSHP + + I RLG G AT KF N ET+V I S+R +DV+IVQSG
Sbjct: 28 VFAGSSHPKLVEGICDRLGTKQGSATLGKFKNGETSVTIHTSIRNKDVFIVQSG 81
>UniRef50_Q64M76 Cluster: Phosphoribosyl pyrophosphate
synthase-like; n=2; Oryza sativa|Rep: Phosphoribosyl
pyrophosphate synthase-like - Oryza sativa subsp.
japonica (Rice)
Length = 183
Score = 59.3 bits (137), Expect = 1e-07
Identities = 28/72 (38%), Positives = 49/72 (68%), Gaps = 7/72 (9%)
Query: 4 IKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRGEDVYIVQSGCGEI 63
+++F+G+++P +A+ + LG+ LGR K+F++ G SVRG D+++VQ+ C
Sbjct: 104 LRIFSGTANPTLAQEVAFYLGMELGRVKIKRFTD-------GGSVRGCDMFLVQATCPPP 156
Query: 64 NDNLMELFIMIN 75
N+N+MEL IMI+
Sbjct: 157 NENMMELLIMID 168
>UniRef50_Q7P228 Cluster: Probable ribose-phosphate diphosphokinase;
n=1; Chromobacterium violaceum|Rep: Probable
ribose-phosphate diphosphokinase - Chromobacterium
violaceum
Length = 270
Score = 58.0 bits (134), Expect = 3e-07
Identities = 48/173 (27%), Positives = 84/173 (48%), Gaps = 13/173 (7%)
Query: 89 VPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFFN-IPVDNLYA 147
+P PY+RQD+ ++AK+ LI+ G V D H+ + + + V++
Sbjct: 76 LPYVPYARQDRVANPGEALSAKVFCGLINQQGYSRVRIQDPHSDVVTALLDRVEVED--P 133
Query: 148 EPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVL 207
PA+ + ++ P + +V+PDAG KR+ +A +L K R S +
Sbjct: 134 LPALRRALEAIGP----ATLVAPDAGARKRVLKLAQQLGCGAVCADKARDTVTGKISGIE 189
Query: 208 V-GDVKNKTAIMVDDLADTCDTILKGAEAL--REAGANK---IYAFLTHGIFA 254
V G + ++VDD+ D T + AEA+ R+A + +Y ++THGIF+
Sbjct: 190 VHGALPAGPLLVVDDICDGGGTFVGLAEAIAARQAAEGQSAPLYLYVTHGIFS 242
>UniRef50_Q4FCY7 Cluster: Phosphoribosyl pyrophosphate synthetase
2; n=2; Bovinae|Rep: Phosphoribosyl pyrophosphate
synthetase 2 - Bos taurus (Bovine)
Length = 82
Score = 56.8 bits (131), Expect = 7e-07
Identities = 24/40 (60%), Positives = 32/40 (80%)
Query: 1 MPNIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKET 40
MPNI +F+GSSH D+++ + RLGL LG+ TKKFSN+ET
Sbjct: 43 MPNIVLFSGSSHQDLSQRVADRLGLELGKVITKKFSNQET 82
>UniRef50_A2FWD0 Cluster: Ribose-phosphate pyrophosphokinase family
protein; n=2; Trichomonas vaginalis G3|Rep:
Ribose-phosphate pyrophosphokinase family protein -
Trichomonas vaginalis G3
Length = 327
Score = 55.6 bits (128), Expect = 2e-06
Identities = 58/245 (23%), Positives = 103/245 (42%), Gaps = 17/245 (6%)
Query: 64 NDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADH 123
+D+++E++ + + R ++P YS ++ +TAK ++S G+
Sbjct: 71 DDDILEVYRVGSTLVQYGVRRRVFIIPFLGYSTMERAVLPGEVVTAKCTIQMLSSIGSGS 130
Query: 124 ----VITIDLHASQIQGFFNIPVDNL--YAEPAITKWIKENIPEWKSSVMVSPDAGGVKR 177
+ DLH + + +F P L Y + A+ K + + + + S D G
Sbjct: 131 NGNVFLLFDLHTAGLLHYFEGPCLRLELYGQKALLKSLPLIGFDPATFMFASADLGRTAW 190
Query: 178 MTGIADRLDIDFAIIHKERQRA---NEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAE 234
+ A A I K R ++ + ++GDVK K ++ DD+ + T++ AE
Sbjct: 191 VNAFARESGTPVAFIRKVRTMVGSISQSQAFEVIGDVKGKHVVIYDDMTRSGGTLVHAAE 250
Query: 235 ALREAGANKIYAFLTHGIFAGNAIEKIN---NSSLEAIVVTNTIP--QEKNMKLCP-KLQ 288
GA + ++H F N + +N NS L IV NT P Q +K P K
Sbjct: 251 KYLSVGALSVDVCVSH--FLPNDKKVLNYLINSPLRKIVALNTHPATQTAQIKAHPEKFV 308
Query: 289 TIDIS 293
+D S
Sbjct: 309 IVDCS 313
>UniRef50_Q8EFJ2 Cluster: Phosphoribosyl transferase domain protein;
n=4; Shewanella|Rep: Phosphoribosyl transferase domain
protein - Shewanella oneidensis
Length = 301
Score = 54.4 bits (125), Expect = 4e-06
Identities = 45/190 (23%), Positives = 88/190 (46%), Gaps = 11/190 (5%)
Query: 66 NLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVI 125
++M+L ++ +A + A ++ ++P P +RQD+ ++ K+ A+LI+ V
Sbjct: 72 SIMQLLLLTDALRRNGAEQIDLLLPYMPGARQDRVCNVGEALSVKVYASLINQQQYASVS 131
Query: 126 TIDLHASQIQGFFN--IPVDNLYAEPAITKWIKENIPEWKSSVMVSPDAGGVKRMTGIAD 183
D H+ + +DN AI + + V+VSPDAG K++ G+A
Sbjct: 132 VFDPHSDVTAALLDRVQVIDNHSFVAAIAAQLTGEL------VLVSPDAGANKKVFGLAK 185
Query: 184 RLD---IDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAG 240
L + A H++ + + V D+ KT ++VDD+ T ++ A L++
Sbjct: 186 ALQGMPVIRADKHRDVVNGHIIATEVFCDDLSGKTCLIVDDICAGGRTFIELAIKLKQKR 245
Query: 241 ANKIYAFLTH 250
A + ++H
Sbjct: 246 AQSVILIVSH 255
>UniRef50_A0CXZ2 Cluster: Chromosome undetermined scaffold_30, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_30,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 340
Score = 54.0 bits (124), Expect = 5e-06
Identities = 23/69 (33%), Positives = 43/69 (62%)
Query: 217 IMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIP 276
I+VDD+ DT T+ + ++ L+E GA +++AF TH +F+G +++ SL+ I+V +P
Sbjct: 184 IIVDDMIDTASTLSEVSKVLKEQGAIRVFAFATHALFSGKEFINLSSPSLDQIIVIIYLP 243
Query: 277 QEKNMKLCP 285
+ + P
Sbjct: 244 FNYYINIIP 252
>UniRef50_A7SHY8 Cluster: Predicted protein; n=2; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 227
Score = 53.6 bits (123), Expect = 6e-06
Identities = 47/197 (23%), Positives = 89/197 (45%), Gaps = 14/197 (7%)
Query: 111 LLANLISVAGADHVITIDLHASQIQGFF-NIPVDNLYAEPAITKWIKENIPEWKSSVMVS 169
L A ++ G ++ D+HA Q + +F + + L + + + N E K ++
Sbjct: 30 LSATPLTARGPTQIVIFDIHALQERFYFGDFVIPRLESAIPLLLRVLSNFQE-KVNIAF- 87
Query: 170 PDAGGVKRMTGIADRLD----IDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADT 225
PD G KR + I K + EG T K I+VDDL T
Sbjct: 88 PDEGAYKRFHTMFQAFPNITCIKIRDGDKRIVKVKEGKFTP-----KGSHVIIVDDLVMT 142
Query: 226 CDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSL--EAIVVTNTIPQEKNMKL 283
T++ A+AL+ AGA+KI A++TH +F + ++ + + E +T+++P K++
Sbjct: 143 GGTLIMCAKALKAAGASKISAYVTHAVFPQESWKRFTSRDVPFEKFYITDSLPHAKDIAS 202
Query: 284 CPKLQTIDISVMLAEAI 300
+ + +++E +
Sbjct: 203 NSPFHLLSLCDVISETL 219
>UniRef50_A6MK41 Cluster: Phosphoribosyl pyrophosphate
synthetase-associated 1-like protein; n=5;
Euteleostomi|Rep: Phosphoribosyl pyrophosphate
synthetase-associated 1-like protein - Callithrix
jacchus (Common marmoset)
Length = 39
Score = 51.2 bits (117), Expect = 3e-05
Identities = 20/33 (60%), Positives = 29/33 (87%)
Query: 284 CPKLQTIDISVMLAEAIRRTHYAESVSYLFTNV 316
CPK++T+DIS++L+EAIRR H ES++YLF N+
Sbjct: 3 CPKIKTVDISLILSEAIRRIHNGESMAYLFRNI 35
>UniRef50_P58860 Cluster: Orotate phosphoribosyltransferase; n=1;
Methanopyrus kandleri|Rep: Orotate
phosphoribosyltransferase - Methanopyrus kandleri
Length = 183
Score = 51.2 bits (117), Expect = 3e-05
Identities = 26/91 (28%), Positives = 52/91 (57%), Gaps = 4/91 (4%)
Query: 150 AITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVG 209
A+T + E +P+ V+ P+ G V ++ ++ + + AI+ K ++ G+ +VG
Sbjct: 49 ALTDALLEVLPD--GDVLAGPELGAVPLVSVLSVKAGLPMAIVRKRKKEYGTGER--IVG 104
Query: 210 DVKNKTAIMVDDLADTCDTILKGAEALREAG 240
DV+ + ++VDD+A T ++L+ EA+ E G
Sbjct: 105 DVRGRKVVLVDDVATTGGSLLEALEAIEEEG 135
>UniRef50_A2XQT7 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (indica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. indica
(Rice)
Length = 165
Score = 47.2 bits (107), Expect = 6e-04
Identities = 28/79 (35%), Positives = 42/79 (53%), Gaps = 5/79 (6%)
Query: 14 DIAKTIVARLGLNLGRATTKKFSNKETNV----EIGESVRGEDVYIVQSGCGEINDNLME 69
+I V R+ L + +F E + +RG DV++VQ C +N+NLM+
Sbjct: 47 NIKNDTVLRIVLGTANPSLSQFVTFEKQIVSSFRFTRKLRGYDVFLVQPTC-PVNENLMD 105
Query: 70 LFIMINACKIASASRVTAV 88
L IM +AC ASA+ +TAV
Sbjct: 106 LLIMTDACMRASANSITAV 124
>UniRef50_Q12V34 Cluster: PyrE-like protein; n=2;
Methanosarcinaceae|Rep: PyrE-like protein -
Methanococcoides burtonii (strain DSM 6242)
Length = 203
Score = 46.4 bits (105), Expect = 0.001
Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 4/110 (3%)
Query: 164 SSVMVSPDAGGVKRMTGIADRLDIDFAIIHK---ERQRANE-GDSTVLVGDVKNKTAIMV 219
+ +++ G+ T +A+ L+IDFAI H ++ + N+ G + DV+ K I+V
Sbjct: 90 ADLVIGIGLSGIPIATMMAEELEIDFAIFHDYDDQKGKTNQRGIFSRNFADVEGKKCIIV 149
Query: 220 DDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAI 269
DD+ + T+ AE LRE GA I + + I + SSL I
Sbjct: 150 DDVVSSGATVTDVAEQLREVGATPIAVAVIVDKMNADMIANVPMSSLVRI 199
>UniRef50_Q9K9W3 Cluster: Orotate phosphoribosyltransferase; n=54;
Bacilli|Rep: Orotate phosphoribosyltransferase -
Bacillus halodurans
Length = 210
Score = 44.8 bits (101), Expect = 0.003
Identities = 29/122 (23%), Positives = 63/122 (51%), Gaps = 9/122 (7%)
Query: 155 IKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVGDVKNK 214
I+ + PE +V+ G+ ++DRL + + + G + G + +K
Sbjct: 58 IRSHFPE--VTVVAGTATAGIPHAAWVSDRLQAPMVYVRSKSK--GHGKQNQIEGKLSSK 113
Query: 215 T-AIMVDDLADTCDTILKGAEALREAGAN--KIYAFLTHGIFAGNAIEKINNSSLEAIVV 271
++++DL T ++++ A+ALREAGA+ + A T+G+ G +++ ++L + V+
Sbjct: 114 DRVVIIEDLISTGGSVIQAADALREAGADVLGVVAIFTYGLEKGQ--DQLEAANLPSYVL 171
Query: 272 TN 273
T+
Sbjct: 172 TD 173
>UniRef50_O08359 Cluster: Orotate phosphoribosyltransferase; n=4;
Sulfolobaceae|Rep: Orotate phosphoribosyltransferase -
Sulfolobus acidocaldarius
Length = 197
Score = 44.4 bits (100), Expect = 0.004
Identities = 32/99 (32%), Positives = 49/99 (49%), Gaps = 3/99 (3%)
Query: 173 GGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKG 232
GGV + IA +L+ I E++ G +L DV K I+VDD+A T +ILK
Sbjct: 67 GGVPFASFIACKLNKPMGYIRAEKK--GHGTERLLEADVDGKKVIVVDDVATTGGSILKA 124
Query: 233 AEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVV 271
E +R+AG +A + G A EK+ + + + V
Sbjct: 125 VEEVRKAGGKVEHALVIVDREEG-AFEKLESVGIRLLSV 162
>UniRef50_Q30L82 Cluster: Gp63; n=1; Listeria phage P100|Rep: Gp63 -
Listeria phage P100
Length = 304
Score = 42.7 bits (96), Expect = 0.012
Identities = 70/303 (23%), Positives = 128/303 (42%), Gaps = 37/303 (12%)
Query: 23 LGLNLGRATTKKFSNKETNVEIGESV---RGEDVYIVQSGCGEINDNLMELFIMINACKI 79
L +N + F N E N+ E++ E I G ++L+ + +++N+ +
Sbjct: 3 LYMNGKKVHESTFPNGEINIMPDENLWVLEEEKAEITWQYSGNGAEDLLAVRLLVNSIRE 62
Query: 80 ASASR--VTAVVPCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVITIDLHASQIQGF 137
+ + V PYSR D+ + ++ P + LL D + ++ H+
Sbjct: 63 HNKKHNSINLTVLYMPYSRMDRLQGNQ-PFS--LLEYFKMFPQVDKLEIVEPHSDVTGSI 119
Query: 138 FNIPVDN--LYAEP-AITKWIKENIPE-----WKSSVMVSPDAGGVKRMTGIADRLDIDF 189
+D+ Y+E A + + E + E W V+V PD G R +A D F
Sbjct: 120 ARKLIDSGTYYSERFATVEMLPEVLAEELSNTWWEPVLVYPDKGAKDRYDKLATDSDYSF 179
Query: 190 AIIHKERQ-----RANEGD-----STVLVGDV---KNKTAIMVDDLADTCDTILKGAEAL 236
+ R+ + + D S LVG+ K TAI+VDDL T +K A
Sbjct: 180 RRATENRRVLFGNKVRDFDTGRIKSLELVGEPPTRKGWTAIIVDDLTSYGGTFVKTATEA 239
Query: 237 REAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTI-----PQE-KNMKLCPKLQTI 290
+ GA+++ + H G+A + S++ + TN++ P+E K ++ KL +
Sbjct: 240 IKLGASRVVLLVAH--MEGSATKGELFESIDKVYTTNSMEASYTPEELKEVERYKKLGLL 297
Query: 291 DIS 293
D++
Sbjct: 298 DVT 300
>UniRef50_Q3IJQ7 Cluster: Putative uncharacterized protein; n=2;
Alteromonadales|Rep: Putative uncharacterized protein -
Pseudoalteromonas haloplanktis (strain TAC 125)
Length = 225
Score = 42.3 bits (95), Expect = 0.016
Identities = 19/56 (33%), Positives = 33/56 (58%)
Query: 194 KERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLT 249
K ++ N D+ + D+ KT +VDD+ T T+ +AL++AGA +++AF T
Sbjct: 165 KAKRVKNLKDAFICTADMSGKTVAIVDDIMTTGATLNAATQALKQAGAKQVWAFTT 220
>UniRef50_Q2FPQ2 Cluster: Orotate phosphoribosyltransferase; n=4;
Methanomicrobiales|Rep: Orotate
phosphoribosyltransferase - Methanospirillum hungatei
(strain JF-1 / DSM 864)
Length = 172
Score = 42.3 bits (95), Expect = 0.016
Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 4/104 (3%)
Query: 140 IPVDNLYAEPAITKWIKENIPEWKSS--VMVSPDAGGVKRMTGIADRLDIDFAIIHKERQ 197
I + PAI K I + + + GGV ++ D + II KE++
Sbjct: 33 IDIKKAITSPAILKKIAAEVLTHSTDFDAVAGVAVGGVPLAVSVSLASDKPYVIIRKEQK 92
Query: 198 RANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGA 241
G +++++GDV K ++V+D+ + + + G E LR AGA
Sbjct: 93 --GHGLASLIIGDVAGKRILLVEDVTTSGGSAVFGIEQLRSAGA 134
>UniRef50_A4TUN0 Cluster: Orotate phosphoribosyltransferase; n=1;
Magnetospirillum gryphiswaldense|Rep: Orotate
phosphoribosyltransferase - Magnetospirillum
gryphiswaldense
Length = 277
Score = 41.5 bits (93), Expect = 0.028
Identities = 29/106 (27%), Positives = 54/106 (50%), Gaps = 6/106 (5%)
Query: 171 DAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKT-AIMVDDLADTCDTI 229
+ G+ I+DRL + + K+ + G + + G+ N ++V+DLA +
Sbjct: 134 ETAGIPYAAWISDRLMVPMLYVRKKPK--GFGRNAQIEGEFANGARVVLVEDLASDGASK 191
Query: 230 LKGAEALREAGANKIYAFLT--HGIFAGNAIEKINNSSLEAIVVTN 273
+ ALREAGA +AF+ +G+F G A++ +N + +E + N
Sbjct: 192 VNFCNALREAGAEVSHAFVVFFYGVFPG-ALKALNETGVELSYLCN 236
>UniRef50_A2BJ25 Cluster: Orotate phosphoribosyltransferase; n=1;
Hyperthermus butylicus DSM 5456|Rep: Orotate
phosphoribosyltransferase - Hyperthermus butylicus
(strain DSM 5456 / JCM 9403)
Length = 201
Score = 41.1 bits (92), Expect = 0.037
Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Query: 166 VMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADT 225
V+V G+ TG+A + A + +R+ G V+ G V+ + ++VDD+A T
Sbjct: 66 VVVGVATAGIIWATGLALLSEKPLAYVRPKRKE--HGLQRVVEGIVEGRRVLVVDDVATT 123
Query: 226 CDTILKGAEALREAGANKIYAFL 248
++ E+LREAGA + A +
Sbjct: 124 GSSLASAVESLREAGAEPVAAMV 146
>UniRef50_O58855 Cluster: Orotate phosphoribosyltransferase; n=3;
Thermococcaceae|Rep: Orotate phosphoribosyltransferase -
Pyrococcus horikoshii
Length = 186
Score = 40.7 bits (91), Expect = 0.048
Identities = 29/110 (26%), Positives = 54/110 (49%), Gaps = 5/110 (4%)
Query: 142 VDNLYAEPAITKWIKENIPEWKSSV--MVSPDAGGVKRMTGIADRLDIDFAIIHKERQRA 199
+ N A I K IKE E + + P+ G V T ++ + I+ K+++
Sbjct: 40 ITNPKALRIIAKLIKEKAEELNLNYDKIAGPELGAVPIATALSLETNKPLLIVRKKKKE- 98
Query: 200 NEGDSTVLVGDV-KNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFL 248
G V+ G+V K ++V+D+ T ++++ A+ LRE GA+ + F+
Sbjct: 99 -HGTGKVIEGNVQKGDKVLLVEDVTTTGGSVIRAAKILREHGADVVGIFV 147
>UniRef50_Q9HM15 Cluster: Orotate phosphoribosyltransferase; n=3;
Thermoplasmatales|Rep: Orotate phosphoribosyltransferase
- Thermoplasma acidophilum
Length = 171
Score = 40.3 bits (90), Expect = 0.064
Identities = 26/106 (24%), Positives = 52/106 (49%), Gaps = 5/106 (4%)
Query: 138 FNIPVDNLYAEPAITKWIKENIPEW-KSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKER 196
+ + + +P++ + I +SS + + G V + A ++ I + I+ KER
Sbjct: 29 YYVDIKEAATDPSVLRKIASEFSGMIRSSKIAGMELGAVPLIVATALQMSIPYIIVRKER 88
Query: 197 QRANEGDSTVLVGDVKNKTAI-MVDDLADTCDTILKGAEALREAGA 241
+ G ++LVG + I +++D+ T +++LK LRE GA
Sbjct: 89 ---SHGTMSLLVGKFEKGEEIDVIEDVVTTGNSVLKAVNTLRENGA 131
>UniRef50_A7HHY1 Cluster: Phosphoribosyltransferase; n=2;
Anaeromyxobacter|Rep: Phosphoribosyltransferase -
Anaeromyxobacter sp. Fw109-5
Length = 251
Score = 39.5 bits (88), Expect = 0.11
Identities = 24/86 (27%), Positives = 44/86 (51%), Gaps = 3/86 (3%)
Query: 162 WKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEG---DSTVLVGDVKNKTAIM 218
++ V+V GGV +A L +DF + E++R + + V + D+ K ++
Sbjct: 118 FRPDVVVGVAKGGVFVGGALAAALGVDFYPVRIEKRRRDAAPLPEPVVELPDLSRKKVLV 177
Query: 219 VDDLADTCDTILKGAEALREAGANKI 244
VDD+A + T+ K R+AGA ++
Sbjct: 178 VDDVASSGATLAKARAVARKAGAREV 203
>UniRef50_Q8PVD0 Cluster: PyrE-like protein; n=5;
Methanosarcinales|Rep: PyrE-like protein -
Methanosarcina mazei (Methanosarcina frisia)
Length = 204
Score = 39.1 bits (87), Expect = 0.15
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 5/81 (6%)
Query: 166 VMVSPDAGGVKRMTGIADRLDIDFAIIHKER-----QRANEGDSTVLVGDVKNKTAIMVD 220
V+V A G+ + +A+ L DFA+ H + Q +G + G V K ++VD
Sbjct: 92 VVVGVAASGIPLASMMANELGADFALYHSRKGQDMVQPGQKGTISRNFGSVAGKNCVIVD 151
Query: 221 DLADTCDTILKGAEALREAGA 241
D+ T T ++ E LRE A
Sbjct: 152 DVITTGSTTMEVIEQLREMDA 172
>UniRef50_A1ZTS6 Cluster: Orotate phosphoribosyltransferase; n=1;
Microscilla marina ATCC 23134|Rep: Orotate
phosphoribosyltransferase - Microscilla marina ATCC
23134
Length = 218
Score = 38.3 bits (85), Expect = 0.26
Identities = 27/100 (27%), Positives = 50/100 (50%), Gaps = 7/100 (7%)
Query: 155 IKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVGDV-KN 213
IK+ P ++ V+ G+ + IAD L++ F + + + G ++ G + K
Sbjct: 64 IKKEYPTVEAIAGVA--TAGIPQGAMIADELELPFLYVRSKAK--GHGKENLVEGKLTKG 119
Query: 214 KTAIMVDDLADTCDTILKGAEALREAGAN--KIYAFLTHG 251
+ ++++D+ T + +K EALREAG I A T+G
Sbjct: 120 QKVVVIEDVLSTGGSSIKAVEALREAGVEVLGIVAMFTYG 159
>UniRef50_A0UWY5 Cluster: Phosphoribosyltransferase; n=1;
Clostridium cellulolyticum H10|Rep:
Phosphoribosyltransferase - Clostridium cellulolyticum
H10
Length = 220
Score = 37.9 bits (84), Expect = 0.34
Identities = 19/59 (32%), Positives = 34/59 (57%), Gaps = 2/59 (3%)
Query: 190 AIIHKERQRANEGDSTVLVGD--VKNKTAIMVDDLADTCDTILKGAEALREAGANKIYA 246
+I+ K + N D+ V + + NK +++DD+ T T+ + +AL+EAGA K+ A
Sbjct: 153 SILKKNERLLNLQDAFVAINQRMIVNKNILLIDDILTTGSTVNQCCKALKEAGAGKVIA 211
>UniRef50_P46534 Cluster: Orotate phosphoribosyltransferase; n=6;
Bacillaceae|Rep: Orotate phosphoribosyltransferase -
Bacillus caldolyticus
Length = 206
Score = 37.9 bits (84), Expect = 0.34
Identities = 23/106 (21%), Positives = 53/106 (50%), Gaps = 8/106 (7%)
Query: 150 AITKWIKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVG 209
A+ + I+ + P+ + +++ A G+ +++RL++ + + +R +G + G
Sbjct: 53 ALAELIRTHFPK---ADLIAGTAAGIPHAAWVSERLELPMCYVRSQAKRHGKGKQ--IEG 107
Query: 210 DVK-NKTAIMVDDLADTCDTILKGAEALREAGAN--KIYAFLTHGI 252
+ + ++++DL T T L AL+EAG + A T+G+
Sbjct: 108 QARPGQRVVVIEDLISTGGTSLAAVRALKEAGCEVLGVAAIFTYGL 153
>UniRef50_Q04H27 Cluster: Orotate phosphoribosyltransferase; n=1;
Oenococcus oeni PSU-1|Rep: Orotate
phosphoribosyltransferase - Oenococcus oeni (strain
BAA-331 / PSU-1)
Length = 211
Score = 37.5 bits (83), Expect = 0.45
Identities = 25/98 (25%), Positives = 48/98 (48%), Gaps = 11/98 (11%)
Query: 155 IKENIPEWKSSVMVS--PDA--------GGVKRMTGIADRLDIDFAIIHKERQRANEGDS 204
I++NI + S +++S PD G+ ++DR++ + + + R +
Sbjct: 50 IRKNIADGLSELIISNYPDVEIIGGVATAGIPHAAFVSDRMNKPMIYV-RSKARDHGSKH 108
Query: 205 TVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGAN 242
+ V NK +++DDL T ++L A ++EAGAN
Sbjct: 109 QIEGAQVDNKKLVLIDDLISTGGSVLAAARTVQEAGAN 146
>UniRef50_Q18CV9 Cluster: Amidophosphoribosyltransferase; n=1;
Clostridium difficile 630|Rep:
Amidophosphoribosyltransferase - Clostridium difficile
(strain 630)
Length = 455
Score = 37.1 bits (82), Expect = 0.60
Identities = 33/130 (25%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Query: 171 DAGGVKRMTGIADRLDIDFAII---HKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCD 227
+A G+K G+ + I +ER+ A + L +K K+ I+VDD
Sbjct: 295 NASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPLSTIIKGKSIILVDDSIVRGT 354
Query: 228 TILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAIVV-TNTIPQEKNMKLCPK 286
T + ++LREAGA +I+ +T A + I+ + ++ +N + + + C
Sbjct: 355 TSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPNRSKLIASSNNVEEMREYIGCDS 414
Query: 287 LQTIDISVML 296
L+ +DI ML
Sbjct: 415 LKFLDIEGML 424
>UniRef50_UPI0000D57455 Cluster: PREDICTED: similar to CG3830-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG3830-PA - Tribolium castaneum
Length = 567
Score = 35.9 bits (79), Expect = 1.4
Identities = 17/63 (26%), Positives = 31/63 (49%)
Query: 181 IADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAG 240
I+D D D +++ +++ + G ST ++K DD+ DT+L + L E
Sbjct: 125 ISDDSDDDIQVVNVDKKTSTAGTSTSTATSNESKAEATEDDIMHLIDTVLDNSNQLNETA 184
Query: 241 ANK 243
AN+
Sbjct: 185 ANQ 187
>UniRef50_Q9V2H4 Cluster: Hypoxanthine guanine
phosphoribosyltransferase; n=4; Thermococcaceae|Rep:
Hypoxanthine guanine phosphoribosyltransferase -
Pyrococcus abyssi
Length = 153
Score = 35.9 bits (79), Expect = 1.4
Identities = 26/97 (26%), Positives = 51/97 (52%), Gaps = 7/97 (7%)
Query: 155 IKENIPEWKSSVMVSPDAGGVKRMTGIADRL-DIDFAIIHKE-----RQRANEGDSTVLV 208
+ E + E+K V+V GG+ ++ L D+ +I + +RA + T+ +
Sbjct: 18 LAEKLREYKPDVIVGVARGGLIPAVRLSHILNDVPLKVIDVKFYKGIDERAEKPVITIPI 77
Query: 209 -GDVKNKTAIMVDDLADTCDTILKGAEALREAGANKI 244
GD+K K ++VDD++DT T+ + +++ GA +I
Sbjct: 78 HGDLKGKKVVIVDDVSDTGKTLEVVIDEVKKLGAKEI 114
>UniRef50_Q9Y9D8 Cluster: Orotate phosphoribosyltransferase; n=1;
Aeropyrum pernix|Rep: Orotate phosphoribosyltransferase
- Aeropyrum pernix
Length = 186
Score = 35.9 bits (79), Expect = 1.4
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 2/78 (2%)
Query: 163 KSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDL 222
+SS ++ GG+ +A RL + ER+ G + + GD ++VDD+
Sbjct: 66 RSSAVIGVATGGLPWAAMLALRLSKPLGYVRPERK--GHGTLSQVEGDPPKGRVVVVDDV 123
Query: 223 ADTCDTILKGAEALREAG 240
A T +I K E LR G
Sbjct: 124 ATTGTSIAKSIEVLRSNG 141
>UniRef50_Q3XYF1 Cluster: Orotate phosphoribosyl transferase; n=3;
Bacilli|Rep: Orotate phosphoribosyl transferase -
Enterococcus faecium DO
Length = 209
Score = 35.5 bits (78), Expect = 1.8
Identities = 28/122 (22%), Positives = 58/122 (47%), Gaps = 9/122 (7%)
Query: 155 IKENIPEWKSSVMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVGDV-KN 213
IKE PE + V+ G+ +A+ LD+ I + + +G+ + G + +
Sbjct: 60 IKEAYPEVQ--VIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDHGKGNQ--IEGRIFEG 115
Query: 214 KTAIMVDDLADTCDTILKGAEALREAGAN--KIYAFLTHGIFAGNAIEKINNSSLEAIVV 271
+ ++++DL T ++L+ AEA + GA+ + A T+ + G A + + + +
Sbjct: 116 QKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGKA--NFEKAEIPLMTL 173
Query: 272 TN 273
TN
Sbjct: 174 TN 175
>UniRef50_Q9HS16 Cluster: PyrE-like protein; n=4;
Halobacteriaceae|Rep: PyrE-like protein - Halobacterium
salinarium (Halobacterium halobium)
Length = 212
Score = 35.5 bits (78), Expect = 1.8
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 7/86 (8%)
Query: 166 VMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVGD-------VKNKTAIM 218
++V + GV T A+ L D A + + +EGD L G V+++ +
Sbjct: 94 LVVGIEKAGVPLATATANELGTDLATYTPRKHQWDEGDMADLGGSFSRNFASVEDRDCFV 153
Query: 219 VDDLADTCDTILKGAEALREAGANKI 244
VDD + TI + +A+REAG +
Sbjct: 154 VDDTVTSGTTITETIQAVREAGGTPV 179
>UniRef50_Q9KFN4 Cluster: ABC transporter; n=22; Firmicutes|Rep: ABC
transporter - Bacillus halodurans
Length = 306
Score = 35.1 bits (77), Expect = 2.4
Identities = 19/73 (26%), Positives = 35/73 (47%), Gaps = 5/73 (6%)
Query: 3 NIKVFTGSSHPDIAKTIVARLGLNLGRATTKKFSNKETNVEIGESVRG-----EDVYIVQ 57
N K+F +SHP++A TI+ G+N+ N ++ EI + V+ DVY +
Sbjct: 227 NRKIFLSTSHPEVAATILQERGINVDTQARGLVMNDRSDEEIAQLVKAFVEKDIDVYRIS 286
Query: 58 SGCGEINDNLMEL 70
+ + ++L
Sbjct: 287 DETSSLEEIFLQL 299
>UniRef50_Q7UQ46 Cluster: Hypoxanthine-guanine
phosphoribosyltransferase; n=2; Planctomycetaceae|Rep:
Hypoxanthine-guanine phosphoribosyltransferase -
Rhodopirellula baltica
Length = 177
Score = 35.1 bits (77), Expect = 2.4
Identities = 17/44 (38%), Positives = 30/44 (68%), Gaps = 1/44 (2%)
Query: 201 EGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKI 244
E DS +L+ DV+N+ ++VDD+ DT T+ K + A+ + GA+ +
Sbjct: 74 EIDSKMLI-DVQNRDVLLVDDIYDTGATLTKLSGAIADMGASSV 116
>UniRef50_Q0ID76 Cluster: PyrF/pyrE bifunctional enzyme; n=5;
Synechococcus|Rep: PyrF/pyrE bifunctional enzyme -
Synechococcus sp. (strain CC9311)
Length = 484
Score = 35.1 bits (77), Expect = 2.4
Identities = 27/109 (24%), Positives = 55/109 (50%), Gaps = 8/109 (7%)
Query: 173 GGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVGDVKN-KTAIMVDDLADTCDTILK 231
G + TG++ L + +I+ ++ G ++ G+ K +T +VDD+ T ++++
Sbjct: 355 GSLPTATGLS--LQLHKPLIYPRKEVKAHGTRRMVEGEFKKGETVAVVDDILITGGSVME 412
Query: 232 GAEALREAGAN--KIYAFLTH-GIFAGNAIEKINNS--SLEAIVVTNTI 275
G L +G N + FL H GI A +++ + L+A++ +TI
Sbjct: 413 GISKLESSGLNVRDVVVFLDHGGIHDLRAKQRLQSHGVKLQAVLTLDTI 461
>UniRef50_A0Y8V6 Cluster: Competence protein ComF, putative; n=1;
marine gamma proteobacterium HTCC2143|Rep: Competence
protein ComF, putative - marine gamma proteobacterium
HTCC2143
Length = 243
Score = 35.1 bits (77), Expect = 2.4
Identities = 15/51 (29%), Positives = 31/51 (60%)
Query: 195 ERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIY 245
+++R+N + + GDV K +VDD+ T T+ + ++ L +AGA +++
Sbjct: 185 DQRRSNMKGAFQMCGDVAGKLVAVVDDVMTTGTTVSEASQCLLKAGATEVH 235
>UniRef50_Q8RCE2 Cluster: Predicted amidophosphoribosyltransferases;
n=3; Thermoanaerobacter|Rep: Predicted
amidophosphoribosyltransferases - Thermoanaerobacter
tengcongensis
Length = 228
Score = 34.7 bits (76), Expect = 3.2
Identities = 19/56 (33%), Positives = 34/56 (60%), Gaps = 2/56 (3%)
Query: 192 IHKERQRAN-EGDSTVLVGD-VKNKTAIMVDDLADTCDTILKGAEALREAGANKIY 245
+H+E + N +G V D ++ K ++VDD+ T T+ + A+AL+E GA ++Y
Sbjct: 164 LHREERMENVKGAFKVTYKDTIEGKNVLLVDDVLTTGATLDECAKALKENGAKEVY 219
>UniRef50_Q89VW6 Cluster: Blr0929 protein; n=5; Bradyrhizobium|Rep:
Blr0929 protein - Bradyrhizobium japonicum
Length = 563
Score = 34.7 bits (76), Expect = 3.2
Identities = 35/115 (30%), Positives = 50/115 (43%), Gaps = 4/115 (3%)
Query: 66 NLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAPITAKLLANL--ISVAGADH 123
NL+ L I A + A R AVV S D+ KS I +L+A + + A D
Sbjct: 409 NLLALNATIEAARAGEAGRGFAVVAAEVKSLSDQTAKSTEEI-GRLIAEIQASTQAAVDA 467
Query: 124 VITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVM-VSPDAGGVKR 177
V T+ H +I G + + + A T+ I +I E S+ VS G V R
Sbjct: 468 VETMGGHIVEIDGVASSVAAAMEQQDAATREIARSISESASAAKEVSAKIGNVSR 522
>UniRef50_Q0KT47 Cluster: Putative uncharacterized protein; n=1;
Shewanella baltica OS195|Rep: Putative uncharacterized
protein - Shewanella baltica OS195
Length = 589
Score = 34.7 bits (76), Expect = 3.2
Identities = 34/116 (29%), Positives = 48/116 (41%), Gaps = 11/116 (9%)
Query: 19 IVARLGLNLGR-ATTKKFSNKETNVEIGES-VRGEDVYIVQSGCGEINDNLMELFIMINA 76
IV LG NL A KFS + V + S +RG D+Y + DNL +LF++ +
Sbjct: 225 IVESLGENLSEFAIDNKFSKSDKEVYLKVSGLRGLDIYTAREKAERKLDNLSDLFMIFSH 284
Query: 77 CKIASASRVTAVVPCF---------PYSRQDKKEKSRAPITAKLLANLISVAGADH 123
S + T V C P S +K SR + +K L I +H
Sbjct: 285 KTQISWNEKTLVTQCCRDSPIVIGKPRSSMEKGFDSRPQVASKKLNTFIRKFRVNH 340
>UniRef50_Q5CX92 Cluster: YbiN-like RNA methylase; n=3;
Cryptosporidium|Rep: YbiN-like RNA methylase -
Cryptosporidium parvum Iowa II
Length = 348
Score = 34.7 bits (76), Expect = 3.2
Identities = 35/119 (29%), Positives = 59/119 (49%), Gaps = 11/119 (9%)
Query: 207 LVGDVKNKTAIMVDDLADTC--DTILKGAEALR---EAGANKIYAFLTHGIFAGNAIEKI 261
L D+K KT I + D C + I +G + L GAN I++ L + I++ N I
Sbjct: 114 LRNDLKTKTCI--EGGTDVCFSELIPRGKQVLGFDIGIGANCIFSLLCNKIYSWNMIG-- 169
Query: 262 NNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAIRRTHYAESVSYLFT--NVPY 318
++ S+E++ V++TI ++ N+ C KL + + I E + + FT N PY
Sbjct: 170 SDISIESLSVSDTIIKKNNLCGCIKLLHQEKPEYILFGILDKTEIEDLKFSFTICNPPY 228
>UniRef50_Q45918 Cluster: Orotate phosphoribosyltransferase; n=2;
Coxiella burnetii|Rep: Orotate phosphoribosyltransferase
- Coxiella burnetii
Length = 209
Score = 34.7 bits (76), Expect = 3.2
Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 3/76 (3%)
Query: 166 VMVSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVGDV-KNKTAIMVDDLAD 224
++ G+ IADRLD+ +I+ + G + G + K + A++V+DL
Sbjct: 69 IVAGTATAGIPHAAWIADRLDLP--MIYVRAKAKTHGKQNQIEGRIRKGQRALIVEDLIS 126
Query: 225 TCDTILKGAEALREAG 240
T + L ALRE G
Sbjct: 127 TGKSALAAGLALREKG 142
>UniRef50_Q314R1 Cluster: ComF family protein; n=1; Desulfovibrio
desulfuricans G20|Rep: ComF family protein -
Desulfovibrio desulfuricans (strain G20)
Length = 251
Score = 34.3 bits (75), Expect = 4.2
Identities = 18/53 (33%), Positives = 30/53 (56%)
Query: 194 KERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYA 246
KE +R N D+ V+ + ++VDD+ T T+ A+AL AGA +++A
Sbjct: 184 KEERRRNLRDAFEADSCVRGRNVLLVDDVMTTGATLEHCAQALYHAGAQQVHA 236
>UniRef50_Q2S305 Cluster: Orotate phosphoribosyltransferase; n=1;
Salinibacter ruber DSM 13855|Rep: Orotate
phosphoribosyltransferase - Salinibacter ruber (strain
DSM 13855)
Length = 225
Score = 34.3 bits (75), Expect = 4.2
Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Query: 174 GVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILKGA 233
G+ +ADR++ A + + +G ++V+DL T + L A
Sbjct: 88 GIPHAAWLADRIEAPMAYVRDSAKGHGQGRRIEGARPGAGDEVVVVEDLISTGRSALNAA 147
Query: 234 EALREAGAN--KIYAFLTHGIFA 254
A+RE GAN + A ++G+ A
Sbjct: 148 AAVRETGANVSAVLAIFSYGLDA 170
>UniRef50_Q04EC9 Cluster: Predicted amidophosphoribosyltransferase;
n=2; Oenococcus oeni|Rep: Predicted
amidophosphoribosyltransferase - Oenococcus oeni (strain
BAA-331 / PSU-1)
Length = 226
Score = 34.3 bits (75), Expect = 4.2
Identities = 18/50 (36%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Query: 196 RQRANEGDSTVLVGD-VKNKTAIMVDDLADTCDTILKGAEALREAGANKI 244
RQR + + L G ++NK+ +++DD+ T T+ + A L EAGA K+
Sbjct: 170 RQRLKKENLFYLTGSSIENKSVLLLDDVYTTGTTLHQTAAVLYEAGAKKV 219
>UniRef50_A2U7L3 Cluster: Late competence protein; n=1; Bacillus
coagulans 36D1|Rep: Late competence protein - Bacillus
coagulans 36D1
Length = 235
Score = 34.3 bits (75), Expect = 4.2
Identities = 14/34 (41%), Positives = 23/34 (67%)
Query: 211 VKNKTAIMVDDLADTCDTILKGAEALREAGANKI 244
++ ++ ++VDD+ T T+ A+ LREAGA KI
Sbjct: 194 IEGRSVLLVDDIYTTGSTVRHAAKVLREAGARKI 227
>UniRef50_A2G5Q2 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 323
Score = 34.3 bits (75), Expect = 4.2
Identities = 28/123 (22%), Positives = 55/123 (44%), Gaps = 6/123 (4%)
Query: 164 SSVMVSPDAGGVKRMTGIADRLDID-FAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDL 222
+ + V P + R I + + D F K+ + ++G +L N+T ++DL
Sbjct: 70 NQIAVGPPESNIFRTLMIGKKNEADRFEDFAKKISKIHQGQVLILKDGAFNQTVSFINDL 129
Query: 223 ADTCDTILKGAEALREA--GANKIYAFLTHGIFAGNAIEKINNSSLEAIVVTNTIPQEKN 280
+ I + E ++E+ NK Y L +F ++I N + +A + T+ EK+
Sbjct: 130 NLLKNNIYRQLEVVKESIRSYNKHYKKLEQTVFQAKGTQQIANETKKAAL---TVLNEKS 186
Query: 281 MKL 283
+ L
Sbjct: 187 VAL 189
>UniRef50_Q8YSY4 Cluster: Bifunctional enzyme pyrF/pyrE [Includes:
Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) (OMP
decarboxylase) (OMPDCase) (OMPdecase); Orotate
phosphoribosyltransferase (EC 2.4.2.10) (OPRT)
(OPRTase)]; n=7; Cyanobacteria|Rep: Bifunctional enzyme
pyrF/pyrE [Includes: Orotidine 5'-phosphate
decarboxylase (EC 4.1.1.23) (OMP decarboxylase)
(OMPDCase) (OMPdecase); Orotate
phosphoribosyltransferase (EC 2.4.2.10) (OPRT)
(OPRTase)] - Anabaena sp. (strain PCC 7120)
Length = 477
Score = 34.3 bits (75), Expect = 4.2
Identities = 22/81 (27%), Positives = 42/81 (51%), Gaps = 5/81 (6%)
Query: 173 GGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVGDVKN-KTAIMVDDLADTCDTILK 231
G + TG+A RL+ KE + G ++ G+ + + ++VDD+ + ++++
Sbjct: 354 GSLPTATGLALRLNCPMIFPRKEVKA--HGTRRLIEGNFRTGEVVVVVDDILISGKSVME 411
Query: 232 GAEALREAGAN--KIYAFLTH 250
GA+ L+ AG N I F+ H
Sbjct: 412 GADKLKSAGLNVHDIVVFIDH 432
>UniRef50_Q41CE1 Cluster: Late competence protein; n=1;
Exiguobacterium sibiricum 255-15|Rep: Late competence
protein - Exiguobacterium sibiricum 255-15
Length = 215
Score = 33.9 bits (74), Expect = 5.6
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 1/58 (1%)
Query: 190 AIIHKERQRANEGDSTV-LVGDVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYA 246
A H+ R E D+ ++ V KT ++VDD+ T T+ + A L EAGA +I A
Sbjct: 151 AFSHQTRHERLERDNPYHVMQPVTGKTILLVDDVYTTGTTLHQAASRLYEAGAKEISA 208
>UniRef50_A6CB14 Cluster: Putative uncharacterized protein; n=1;
Planctomyces maris DSM 8797|Rep: Putative
uncharacterized protein - Planctomyces maris DSM 8797
Length = 666
Score = 33.9 bits (74), Expect = 5.6
Identities = 19/86 (22%), Positives = 46/86 (53%), Gaps = 2/86 (2%)
Query: 103 SRAPITAKLLANLISVAGADHVITIDLHASQIQGFFNIPVDNLYAEPAITKWIKENIPEW 162
S+ + A++ + IS+ + I + A Q + I VD + + P + W++ ++ E+
Sbjct: 382 SQMKVDARIHESKISMINQGLPVDIRVDAFPEQLYRGI-VDQVSSVPISSNWMRPDLKEY 440
Query: 163 KSSVMVSPDAGGVKRM-TGIADRLDI 187
K+++ + PD G + ++ G+ ++I
Sbjct: 441 KATIRILPDNGDITKLKPGLTAEIEI 466
>UniRef50_Q9NF11 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 214
Score = 33.9 bits (74), Expect = 5.6
Identities = 17/68 (25%), Positives = 34/68 (50%), Gaps = 4/68 (5%)
Query: 185 LDIDFAIIHKERQRANEGDSTVL----VGDVKNKTAIMVDDLADTCDTILKGAEALREAG 240
+ +DF + + + G ++ + ++K K+ ++VDD++DT T+ K L E G
Sbjct: 90 MTVDFIRVKSYEDQMSTGQIQIMGLSNLDELKGKSVLVVDDISDTGRTLAKLLSTLHETG 149
Query: 241 ANKIYAFL 248
K + L
Sbjct: 150 VEKTWTAL 157
>UniRef50_Q8SR76 Cluster: T COMPLEX PROTEIN 1 GAMMA SUBUNIT; n=1;
Encephalitozoon cuniculi|Rep: T COMPLEX PROTEIN 1 GAMMA
SUBUNIT - Encephalitozoon cuniculi
Length = 519
Score = 33.9 bits (74), Expect = 5.6
Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
Query: 131 ASQIQGFFNIPVDNLYAEPAITKWIKE-NIPEWKSSVMVSPDAGGVKRMTGIADRLDIDF 189
AS+I +P+ NL E ++KE N + K+++ V GG + + D + I+
Sbjct: 158 ASKICNILKVPIGNLALEAVKKVYVKEENKCDLKNNMKVEKVLGGNLMESEVVDGVLINK 217
Query: 190 AIIHKERQRANEGDSTVLV 208
IIH + +R E V++
Sbjct: 218 DIIHPQMRRVIENPRIVII 236
>UniRef50_A6GFD2 Cluster: Cytochrome P450; n=1; Plesiocystis
pacifica SIR-1|Rep: Cytochrome P450 - Plesiocystis
pacifica SIR-1
Length = 403
Score = 33.5 bits (73), Expect = 7.3
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 8/86 (9%)
Query: 101 EKSRAPITAKLLANLISVAGADHVITIDLHASQIQGFFNIP--VDNLYAEPAITKWIKEN 158
EK ++LAN + + A H T +L A+ F+ P ++ L AEP +T E
Sbjct: 222 EKEEQISAEEILANCVLLLFAGHETTANLIANGTVALFDHPEQLERLRAEPELTANAVEE 281
Query: 159 IPEWKSSVMVSPDAGGVKRMTGIADR 184
+ W+ AG RM G A R
Sbjct: 282 MLRWEG------PAGSTMRMNGAAPR 301
>UniRef50_A4XK15 Cluster: Phosphoribosyltransferase; n=1;
Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
Phosphoribosyltransferase - Caldicellulosiruptor
saccharolyticus (strain ATCC 43494 / DSM 8903)
Length = 232
Score = 33.5 bits (73), Expect = 7.3
Identities = 15/35 (42%), Positives = 24/35 (68%)
Query: 211 VKNKTAIMVDDLADTCDTILKGAEALREAGANKIY 245
VK KT ++VDD+ T T + ++ L ++GANK+Y
Sbjct: 186 VKGKTVLLVDDIFTTGATADECSKVLLKSGANKVY 220
>UniRef50_Q9P8F6 Cluster: Cephalosporin C regulator 1; n=1;
Acremonium chrysogenum|Rep: Cephalosporin C regulator 1
- Cephalosporium acremonium (Acremonium chrysogenum)
Length = 830
Score = 33.5 bits (73), Expect = 7.3
Identities = 40/145 (27%), Positives = 64/145 (44%), Gaps = 19/145 (13%)
Query: 90 PCFPYSRQDKKEKSRAPITAKLLANLISVAGADHVIT----IDLHASQIQGFFNIPVDNL 145
P P+ + + A + A A L S+A A I L+ S G +PV L
Sbjct: 416 PIDPFLPPHTDKDAAASLVALYRAQLTSLAEAFRYIRDKSFFHLYTS-FHGTLTMPVQKL 474
Query: 146 YAEPAITKWIKE-------NIPE--WKSSVMVSPDAGGVKRMTGIADRL---DIDFAIIH 193
+A P+I WI+E + + + S++V P+ + RM IADRL +D H
Sbjct: 475 FAHPSIAPWIEECDLVLYQRLTKFAFTMSLVVVPNV-YLNRMRSIADRLVPHIVDVFGGH 533
Query: 194 KER-QRANEGDSTVLVGDVKNKTAI 217
E +A G + + VG ++ T +
Sbjct: 534 PEHVVQAKAGPAAIFVGILERMTRV 558
>UniRef50_Q6ABA4 Cluster: Putative uncharacterized protein; n=1;
Propionibacterium acnes|Rep: Putative uncharacterized
protein - Propionibacterium acnes
Length = 240
Score = 33.1 bits (72), Expect = 9.7
Identities = 25/94 (26%), Positives = 45/94 (47%), Gaps = 5/94 (5%)
Query: 47 SVRGEDVYIVQSGCGEINDNLMELFIMINACKIASASRVTAVVPCFPYSRQDKKEKSRAP 106
S G D + QS G + + + + ++ ++R+ +V RQ K KS+
Sbjct: 92 SPAGCDAALRQSSLGLTSHEISDTLVAVSD---KPSTRI--IVTTAMSDRQKKAYKSQEE 146
Query: 107 ITAKLLANLISVAGADHVITIDLHASQIQGFFNI 140
T+K +S G +H + I++ AS I+G+ NI
Sbjct: 147 QTSKCGHTTLSTQGVNHGLEINIKASPIKGYENI 180
>UniRef50_Q67M40 Cluster: Conserved domain protein; n=1;
Symbiobacterium thermophilum|Rep: Conserved domain
protein - Symbiobacterium thermophilum
Length = 928
Score = 33.1 bits (72), Expect = 9.7
Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 5/81 (6%)
Query: 172 AGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVGDVKNKTAIMVDDLADTCDTILK 231
A GV++ T LD++F ++ R RA E S V + V A +L
Sbjct: 801 ARGVEKSTA----LDLEFGKTYQVRMRAGETHSYRFVAQKGDTAGFTVSSDAPVSLYLLD 856
Query: 232 GA-EALREAGANKIYAFLTHG 251
+ L + GAN+IYAF G
Sbjct: 857 ASGRLLADVGANRIYAFTAEG 877
>UniRef50_Q0LJ69 Cluster: Aldehyde dehydrogenase; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Aldehyde dehydrogenase -
Herpetosiphon aurantiacus ATCC 23779
Length = 537
Score = 33.1 bits (72), Expect = 9.7
Identities = 23/88 (26%), Positives = 45/88 (51%), Gaps = 7/88 (7%)
Query: 100 KEKSRAPITAKLLANLISVA-GADHVITIDLHASQIQGFFNIPVDNLY--AEPAITKWIK 156
+ R P TA+++AN+I+ A +HV ++ + ++P D+++ P I +++
Sbjct: 205 RPSERMPHTAQVVANIIATAFKPEHVTSVVGDVDTAEALLDLPFDHIFFTGSPRIGQYVM 264
Query: 157 ENIPEWKSSVMVSPDAGGVKRMTGIADR 184
+ E SSV + + GG + I DR
Sbjct: 265 QRAAEHFSSVTL--ELGG--KSPAIVDR 288
>UniRef50_A7N438 Cluster: Putative uncharacterized protein; n=1;
Vibrio harveyi ATCC BAA-1116|Rep: Putative
uncharacterized protein - Vibrio harveyi ATCC BAA-1116
Length = 432
Score = 33.1 bits (72), Expect = 9.7
Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 4/54 (7%)
Query: 250 HGI---FAGNAIEKINNSSLEAIVVTNTIPQEKNMKLCPKLQTIDISVMLAEAI 300
HGI AG+AI + NS +EAI V T P+ K+ L TID + +A+
Sbjct: 132 HGIDVTLAGSAINNLKNSDVEAIEVP-TAPKALRKKIAEILSTIDNQIDATQAL 184
>UniRef50_A4FCI4 Cluster: Phosphoribosyltransferase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
Phosphoribosyltransferase - Saccharopolyspora erythraea
(strain NRRL 23338)
Length = 209
Score = 33.1 bits (72), Expect = 9.7
Identities = 23/95 (24%), Positives = 45/95 (47%), Gaps = 5/95 (5%)
Query: 210 DVKNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFLTHGIFAGNAIEKINNSSLEAI 269
DV+ +TAI+VDD T T E GA ++ L + A+E++ + E +
Sbjct: 103 DVRGRTAIVVDDGIRTGSTAHTACRVAHELGAAEV--VLAVPVAPPQALERLEEVTDEQV 160
Query: 270 VVTNTIPQE---KNMKLCPKLQTIDISVMLAEAIR 301
+ P E ++ + P ++ ++S +L A++
Sbjct: 161 CLATVGPAEPISRSYRCFPPVRDAEVSRLLRRAVQ 195
>UniRef50_A3DJU7 Cluster: Methyl-accepting chemotaxis sensory
transducer precursor; n=2; Clostridium|Rep:
Methyl-accepting chemotaxis sensory transducer precursor
- Clostridium thermocellum (strain ATCC 27405 / DSM
1237)
Length = 832
Score = 33.1 bits (72), Expect = 9.7
Identities = 35/106 (33%), Positives = 47/106 (44%), Gaps = 7/106 (6%)
Query: 131 ASQIQGFFNIPVDNLYAEPAITKWIKENIPEWKSSVMVSPDA--GGVKRMT-GIADRLDI 187
A + G FN+ V NL I + E K V + +A GG K + GI LD
Sbjct: 410 AGDLTGAFNVMVTNLKQLKNEIDSITMAVEEGKLGVRGNEEAFKGGWKELLKGINKTLDA 469
Query: 188 DFAIIHKER---QRANEGDSTVLV-GDVKNKTAIMVDDLADTCDTI 229
A I + Q +G+ V V GD K + AI+ D+L T D I
Sbjct: 470 VIAPIREASLVLQEVAKGNLNVAVTGDYKGENAIIKDNLNMTIDNI 515
>UniRef50_A3DHM1 Cluster: Phosphoribosyltransferase; n=1;
Clostridium thermocellum ATCC 27405|Rep:
Phosphoribosyltransferase - Clostridium thermocellum
(strain ATCC 27405 / DSM 1237)
Length = 220
Score = 33.1 bits (72), Expect = 9.7
Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 7/96 (7%)
Query: 156 KENIPEWKSSVMVSPDAG---GVKRMTGIADRLDIDFA--IIHKERQRANEGDSTVLV-- 208
+E + S +++ + G G+K I R+ ++ ++ KE + N D+ +
Sbjct: 115 RERSRGYNQSYLIARELGRELGIKNEAKILKRVRNTYSQSLLKKEDRLVNVKDAFRITDR 174
Query: 209 GDVKNKTAIMVDDLADTCDTILKGAEALREAGANKI 244
V+ K +VDD+ T T+ + + L+EAGA KI
Sbjct: 175 SKVEGKAMFLVDDILTTGTTLNECSRVLKEAGAKKI 210
>UniRef50_A7D3I4 Cluster: Phosphoribosyltransferase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Phosphoribosyltransferase
- Halorubrum lacusprofundi ATCC 49239
Length = 225
Score = 33.1 bits (72), Expect = 9.7
Identities = 21/84 (25%), Positives = 38/84 (45%), Gaps = 7/84 (8%)
Query: 168 VSPDAGGVKRMTGIADRLDIDFAIIHKERQRANEGDSTVLVGD-------VKNKTAIMVD 220
V + G T +A++LD D + + +EGD G ++N+ +VD
Sbjct: 110 VGIEKAGAPLATAVANQLDTDLGTYAPAKHQWDEGDIDEQGGGFSRNFAAIRNRDCYVVD 169
Query: 221 DLADTCDTILKGAEALREAGANKI 244
D+ + T+ + +A+RE G I
Sbjct: 170 DIITSGTTMRESIDAIREQGGEPI 193
>UniRef50_O27888 Cluster: Orotate phosphoribosyltransferase; n=2;
Euryarchaeota|Rep: Orotate phosphoribosyltransferase -
Methanobacterium thermoautotrophicum
Length = 180
Score = 33.1 bits (72), Expect = 9.7
Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 5/114 (4%)
Query: 138 FNIPVDNLYAEPAITKWIKENIPEWKSSV--MVSPDAGGVKRMTGIADRLDIDFAIIHKE 195
+ + + EPA+ I I + V + P G V T ++ +I KE
Sbjct: 38 YYVDIKRAVTEPAVLDVIARLIADAAGEVDRIAGPALGAVPIATAVSLYSRKPLLMIRKE 97
Query: 196 RQRANEGDSTVLVGDV-KNKTAIMVDDLADTCDTILKGAEALREAGANKIYAFL 248
++ G S ++ GD+ K +V+D+ T ++LK A++E G AF+
Sbjct: 98 KK--GYGTSKLIEGDLQKGDRVAVVEDVTTTGGSLLKAVRAIQENGGIVEKAFV 149
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.133 0.377
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 316,912,689
Number of Sequences: 1657284
Number of extensions: 12067211
Number of successful extensions: 31512
Number of sequences better than 10.0: 208
Number of HSP's better than 10.0 without gapping: 161
Number of HSP's successfully gapped in prelim test: 47
Number of HSP's that attempted gapping in prelim test: 31031
Number of HSP's gapped (non-prelim): 248
length of query: 318
length of database: 575,637,011
effective HSP length: 101
effective length of query: 217
effective length of database: 408,251,327
effective search space: 88590537959
effective search space used: 88590537959
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 72 (33.1 bits)
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