Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001568-TA|BGIBMGA001568-PA|IPR000519|P-type trefoil,
IPR000322|Glycoside hydrolase, family 31
(337 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X55080-1|CAC12967.1| 952|Homo sapiens acid alpha-glucosidase pr... 51 7e-06
M34424-1|AAA52506.1| 952|Homo sapiens GAA protein. 51 7e-06
BC040431-1|AAH40431.1| 952|Homo sapiens glucosidase, alpha; aci... 51 7e-06
Y00839-1|CAA68763.1| 952|Homo sapiens glucan 1, 4-alpha-glucosi... 48 5e-05
DQ907243-1|ABI53718.1| 952|Homo sapiens alpha-glucosidase protein. 48 5e-05
BC120872-1|AAI20873.1| 1857|Homo sapiens maltase-glucoamylase (a... 46 3e-04
AF432202-1|AAL83560.1| 1734|Homo sapiens maltase-glucoamylase pr... 46 3e-04
AF016833-1|AAC39568.2| 1857|Homo sapiens maltase-glucoamylase pr... 46 3e-04
Y00839-2|CAA68764.1| 749|Homo sapiens 70 kD alpha-glucosidase p... 42 0.004
X63597-1|CAA45140.1| 1827|Homo sapiens prosucrose-isomaltase pro... 38 0.038
M22616-1|AAA60551.1| 679|Homo sapiens SI protein. 38 0.038
BC132860-1|AAI32861.1| 1827|Homo sapiens sucrase-isomaltase (alp... 38 0.038
BC132834-1|AAI32835.1| 1827|Homo sapiens sucrase-isomaltase (alp... 38 0.038
BC116452-1|AAI16453.1| 1827|Homo sapiens sucrase-isomaltase (alp... 38 0.038
BC115034-1|AAI15035.1| 1827|Homo sapiens sucrase-isomaltase (alp... 38 0.038
BC111975-1|AAI11976.1| 482|Homo sapiens maltase-glucoamylase-li... 38 0.038
BC111973-1|AAI11974.1| 482|Homo sapiens maltase-glucoamylase-li... 38 0.038
AC073647-1|AAS07445.1| 327|Homo sapiens unknown protein. 37 0.12
U25657-1|AAA83628.1| 80|Homo sapiens intestinal trefoil factor... 33 1.1
L15203-1|AAA59981.1| 80|Homo sapiens secretory protein protein. 33 1.1
L08044-1|AAA36766.1| 74|Homo sapiens intestinal trefoil factor... 33 1.1
BC017859-1|AAH17859.1| 73|Homo sapiens TFF3 protein protein. 33 1.1
AP001746-2|BAA95531.1| 73|Homo sapiens trefoil factor 3, HITF,... 33 1.1
AB038162-3|BAB13731.1| 73|Homo sapiens trefoil factor 3 protein. 33 1.1
AK131337-1|BAD18495.1| 646|Homo sapiens protein ( Homo sapiens ... 33 1.9
>X55080-1|CAC12967.1| 952|Homo sapiens acid alpha-glucosidase
protein.
Length = 952
Score = 50.8 bits (116), Expect = 7e-06
Identities = 66/296 (22%), Positives = 120/296 (40%), Gaps = 38/296 (12%)
Query: 78 CLVARTLRLPCGYAN-VNSEQCHPH-CCY----------DFRSKTCFHRFPSRFSYVMDR 125
C V R C + EQC CCY CF PS SY ++
Sbjct: 82 CDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFP-PSYPSYKLEN 140
Query: 126 VWDEDVVLSARVA-TIPFSFQNSLPRIKLSIDEVSKSHLSLNFYNPAL------VEIPH- 177
+ ++ +A + T P F + ++L + +++ L +PA +E PH
Sbjct: 141 LSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETPHV 200
Query: 178 GNRLEEKNYFYDVASPELNVVVNST--ERMIFNTNRGPLVASQNIWELTFWLTNESMYGL 235
+R Y + + V+V R++ NT PL + +L+ L ++ + GL
Sbjct: 201 HSRAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGL 260
Query: 236 GE--IPLEKTTK----VLYNHN------GGISGI-PLIFA-KSGHSYHGILIEAVAPTVI 281
E PL +T L+N + + G P A + G S HG+ + +
Sbjct: 261 AEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAMDV 320
Query: 282 TIRKENQIVLRSITSLGVKLHLFVGPKPADIMRDVRNLLGVNKRMEYWMFGAHICR 337
++ + RS + + +++F+GP+P +++ +++G YW G H+CR
Sbjct: 321 VLQPSPALSWRSTGGI-LDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCR 375
>M34424-1|AAA52506.1| 952|Homo sapiens GAA protein.
Length = 952
Score = 50.8 bits (116), Expect = 7e-06
Identities = 66/296 (22%), Positives = 120/296 (40%), Gaps = 38/296 (12%)
Query: 78 CLVARTLRLPCGYAN-VNSEQCHPH-CCY----------DFRSKTCFHRFPSRFSYVMDR 125
C V R C + EQC CCY CF PS SY ++
Sbjct: 82 CDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFP-PSYPSYKLEN 140
Query: 126 VWDEDVVLSARVA-TIPFSFQNSLPRIKLSIDEVSKSHLSLNFYNPAL------VEIPH- 177
+ ++ +A + T P F + ++L + +++ L +PA +E PH
Sbjct: 141 LSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETPHV 200
Query: 178 GNRLEEKNYFYDVASPELNVVVNST--ERMIFNTNRGPLVASQNIWELTFWLTNESMYGL 235
+R Y + + V+V R++ NT PL + +L+ L ++ + GL
Sbjct: 201 HSRAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGL 260
Query: 236 GE--IPLEKTTK----VLYNHN------GGISGI-PLIFA-KSGHSYHGILIEAVAPTVI 281
E PL +T L+N + + G P A + G S HG+ + +
Sbjct: 261 AEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAMDV 320
Query: 282 TIRKENQIVLRSITSLGVKLHLFVGPKPADIMRDVRNLLGVNKRMEYWMFGAHICR 337
++ + RS + + +++F+GP+P +++ +++G YW G H+CR
Sbjct: 321 VLQPSPALSWRSTGGI-LDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCR 375
>BC040431-1|AAH40431.1| 952|Homo sapiens glucosidase, alpha; acid
(Pompe disease, glycogen storage disease type II)
protein.
Length = 952
Score = 50.8 bits (116), Expect = 7e-06
Identities = 66/296 (22%), Positives = 120/296 (40%), Gaps = 38/296 (12%)
Query: 78 CLVARTLRLPCGYAN-VNSEQCHPH-CCY----------DFRSKTCFHRFPSRFSYVMDR 125
C V R C + EQC CCY CF PS SY ++
Sbjct: 82 CDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFP-PSYPSYKLEN 140
Query: 126 VWDEDVVLSARVA-TIPFSFQNSLPRIKLSIDEVSKSHLSLNFYNPAL------VEIPH- 177
+ ++ +A + T P F + ++L + +++ L +PA +E PH
Sbjct: 141 LSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETPHV 200
Query: 178 GNRLEEKNYFYDVASPELNVVVNST--ERMIFNTNRGPLVASQNIWELTFWLTNESMYGL 235
+R Y + + V+V R++ NT PL + +L+ L ++ + GL
Sbjct: 201 HSRAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGL 260
Query: 236 GE--IPLEKTTK----VLYNHN------GGISGI-PLIFA-KSGHSYHGILIEAVAPTVI 281
E PL +T L+N + + G P A + G S HG+ + +
Sbjct: 261 AEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAMDV 320
Query: 282 TIRKENQIVLRSITSLGVKLHLFVGPKPADIMRDVRNLLGVNKRMEYWMFGAHICR 337
++ + RS + + +++F+GP+P +++ +++G YW G H+CR
Sbjct: 321 VLQPSPALSWRSTGGI-LDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCR 375
>Y00839-1|CAA68763.1| 952|Homo sapiens glucan 1,
4-alpha-glucosidase protein.
Length = 952
Score = 48.0 bits (109), Expect = 5e-05
Identities = 65/296 (21%), Positives = 120/296 (40%), Gaps = 38/296 (12%)
Query: 78 CLVARTLRLPCGYAN-VNSEQCHPH-CCY----------DFRSKTCFHRFPSRFSYVMDR 125
C V R C + EQC CCY CF PS SY ++
Sbjct: 82 CDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFP-PSYPSYKLEN 140
Query: 126 VWDEDVVLSARVA-TIPFSFQNSLPRIKLSIDEVSKSHLSLNFYNPAL------VEIPH- 177
+ ++ +A + T P F + ++L + +++ L +PA +E P
Sbjct: 141 LSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETPRV 200
Query: 178 GNRLEEKNYFYDVASPELNVVVNST--ERMIFNTNRGPLVASQNIWELTFWLTNESMYGL 235
+R Y + + V+V+ R++ NT PL + +L+ L ++ + GL
Sbjct: 201 HSRAPSPLYSVEFSEEPFGVIVHRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGL 260
Query: 236 GE--IPLEKTTK----VLYNHN------GGISGI-PLIFA-KSGHSYHGILIEAVAPTVI 281
E PL +T L+N + + G P A + G S HG+ + +
Sbjct: 261 AEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAMDV 320
Query: 282 TIRKENQIVLRSITSLGVKLHLFVGPKPADIMRDVRNLLGVNKRMEYWMFGAHICR 337
++ + RS + + +++F+GP+P +++ +++G YW G H+CR
Sbjct: 321 VLQPSPALSWRSTGGI-LDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCR 375
>DQ907243-1|ABI53718.1| 952|Homo sapiens alpha-glucosidase protein.
Length = 952
Score = 48.0 bits (109), Expect = 5e-05
Identities = 65/296 (21%), Positives = 120/296 (40%), Gaps = 38/296 (12%)
Query: 78 CLVARTLRLPCGYAN-VNSEQCHPH-CCY----------DFRSKTCFHRFPSRFSYVMDR 125
C V R C + EQC CCY CF PS SY ++
Sbjct: 82 CDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFP-PSYPSYKLEN 140
Query: 126 VWDEDVVLSARVA-TIPFSFQNSLPRIKLSIDEVSKSHLSLNFYNPAL------VEIPH- 177
+ ++ +A + T P F + ++L + +++ L +PA +E P
Sbjct: 141 LSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETPRV 200
Query: 178 GNRLEEKNYFYDVASPELNVVVNST--ERMIFNTNRGPLVASQNIWELTFWLTNESMYGL 235
+R Y + + V+V+ R++ NT PL + +L+ L ++ + GL
Sbjct: 201 HSRAPSPLYSVEFSEEPFGVIVHRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGL 260
Query: 236 GE--IPLEKTTK----VLYNHN------GGISGI-PLIFA-KSGHSYHGILIEAVAPTVI 281
E PL +T L+N + + G P A + G S HG+ + +
Sbjct: 261 AEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAMDV 320
Query: 282 TIRKENQIVLRSITSLGVKLHLFVGPKPADIMRDVRNLLGVNKRMEYWMFGAHICR 337
++ + RS + + +++F+GP+P +++ +++G YW G H+CR
Sbjct: 321 VLQPSPALSWRSTGGI-LDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCR 375
>BC120872-1|AAI20873.1| 1857|Homo sapiens maltase-glucoamylase
(alpha-glucosidase) protein.
Length = 1857
Score = 45.6 bits (103), Expect = 3e-04
Identities = 54/235 (22%), Positives = 104/235 (44%), Gaps = 33/235 (14%)
Query: 134 SARVATIPFS--FQNSLPRIKLSIDEVSKS--HLSLNFYNPALVEIPH-------GNRLE 182
+AR+ +P S F +++ + L+ + + + H L E+PH GN
Sbjct: 152 TARLKNLPSSPVFGSNVDNVLLTAEYQTSNRFHFKLTDQTNNRFEVPHEHVQSFSGNAAA 211
Query: 183 EKNYFYDVASPELNVVVN--STERMIFNTNRGPLVASQNIWELTFWLTNESMYGLGEIPL 240
Y +++ ++ V S R++F+++ GPL+ + +L+ L + ++YGLGE
Sbjct: 212 SLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLLFADQFLQLSTRLPSTNVYGLGEHVH 271
Query: 241 E--------KTTKVLY-----NHNG-GISGIPLIFA----KSGHSYHGILIEAVAPTVIT 282
+ KT + N NG + G F SG S+ L+ + A V+
Sbjct: 272 QQYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQTFFLCLEDASGLSFGVFLMNSNAMEVV- 330
Query: 283 IRKENQIVLRSITSLGVKLHLFVGPKPADIMRDVRNLLGVNKRMEYWMFGAHICR 337
++ I R+I + + ++F+G P ++++ L+G YW G H+ R
Sbjct: 331 LQPAPAITYRTIGGI-LDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSR 384
Score = 33.5 bits (73), Expect = 1.1
Identities = 17/71 (23%), Positives = 33/71 (46%), Gaps = 1/71 (1%)
Query: 267 SYHGILIEAVAPTVITIRKENQIVLRSITSLGVKLHLFVGPKPADIMRDVRNLLGVNKRM 326
S HG+L+ +T + + R+ + + ++F+GP P + + L+G +
Sbjct: 1181 SAHGVLLLNSNAMDVTFQPLPALTYRTTGGV-LDFYVFLGPTPELVTQQYTELIGRPVMV 1239
Query: 327 EYWMFGAHICR 337
YW G +CR
Sbjct: 1240 PYWSLGFQLCR 1250
>AF432202-1|AAL83560.1| 1734|Homo sapiens maltase-glucoamylase
protein.
Length = 1734
Score = 45.6 bits (103), Expect = 3e-04
Identities = 54/235 (22%), Positives = 104/235 (44%), Gaps = 33/235 (14%)
Query: 134 SARVATIPFS--FQNSLPRIKLSIDEVSKS--HLSLNFYNPALVEIPH-------GNRLE 182
+AR+ +P S F +++ + L+ + + + H L E+PH GN
Sbjct: 29 TARLKNLPSSPVFGSNVDNVLLTAEYQTSNRFHFKLTDQTNNRFEVPHEHVQSFSGNAAA 88
Query: 183 EKNYFYDVASPELNVVVN--STERMIFNTNRGPLVASQNIWELTFWLTNESMYGLGEIPL 240
Y +++ ++ V S R++F+++ GPL+ + +L+ L + ++YGLGE
Sbjct: 89 SLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLLFADQFLQLSTRLPSTNVYGLGEHVH 148
Query: 241 E--------KTTKVLY-----NHNG-GISGIPLIFA----KSGHSYHGILIEAVAPTVIT 282
+ KT + N NG + G F SG S+ L+ + A V+
Sbjct: 149 QQYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQTFFLCLEDASGLSFGVFLMNSNAMEVV- 207
Query: 283 IRKENQIVLRSITSLGVKLHLFVGPKPADIMRDVRNLLGVNKRMEYWMFGAHICR 337
++ I R+I + + ++F+G P ++++ L+G YW G H+ R
Sbjct: 208 LQPAPAITYRTIGGI-LDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSR 261
Score = 33.5 bits (73), Expect = 1.1
Identities = 17/71 (23%), Positives = 33/71 (46%), Gaps = 1/71 (1%)
Query: 267 SYHGILIEAVAPTVITIRKENQIVLRSITSLGVKLHLFVGPKPADIMRDVRNLLGVNKRM 326
S HG+L+ +T + + R+ + + ++F+GP P + + L+G +
Sbjct: 1058 SAHGVLLLNSNAMDVTFQPLPALTYRTTGGV-LDFYVFLGPTPELVTQQYTELIGRPVMV 1116
Query: 327 EYWMFGAHICR 337
YW G +CR
Sbjct: 1117 PYWSLGFQLCR 1127
>AF016833-1|AAC39568.2| 1857|Homo sapiens maltase-glucoamylase
protein.
Length = 1857
Score = 45.6 bits (103), Expect = 3e-04
Identities = 54/235 (22%), Positives = 104/235 (44%), Gaps = 33/235 (14%)
Query: 134 SARVATIPFS--FQNSLPRIKLSIDEVSKS--HLSLNFYNPALVEIPH-------GNRLE 182
+AR+ +P S F +++ + L+ + + + H L E+PH GN
Sbjct: 152 TARLKNLPSSPVFGSNVDNVLLTAEYQTSNRFHFKLTDQTNNRFEVPHEHVQSFSGNAAA 211
Query: 183 EKNYFYDVASPELNVVVN--STERMIFNTNRGPLVASQNIWELTFWLTNESMYGLGEIPL 240
Y +++ ++ V S R++F+++ GPL+ + +L+ L + ++YGLGE
Sbjct: 212 SLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLLFADQFLQLSTRLPSTNVYGLGEHVH 271
Query: 241 E--------KTTKVLY-----NHNG-GISGIPLIFA----KSGHSYHGILIEAVAPTVIT 282
+ KT + N NG + G F SG S+ L+ + A V+
Sbjct: 272 QQYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQTFFLCLEDASGLSFGVFLMNSNAMEVV- 330
Query: 283 IRKENQIVLRSITSLGVKLHLFVGPKPADIMRDVRNLLGVNKRMEYWMFGAHICR 337
++ I R+I + + ++F+G P ++++ L+G YW G H+ R
Sbjct: 331 LQPAPAITYRTIGGI-LDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSR 384
Score = 33.5 bits (73), Expect = 1.1
Identities = 17/71 (23%), Positives = 33/71 (46%), Gaps = 1/71 (1%)
Query: 267 SYHGILIEAVAPTVITIRKENQIVLRSITSLGVKLHLFVGPKPADIMRDVRNLLGVNKRM 326
S HG+L+ +T + + R+ + + ++F+GP P + + L+G +
Sbjct: 1181 SAHGVLLLNSNAMDVTFQPLPALTYRTTGGV-LDFYVFLGPTPELVTQQYTELIGRPVMV 1239
Query: 327 EYWMFGAHICR 337
YW G +CR
Sbjct: 1240 PYWSLGFQLCR 1250
>Y00839-2|CAA68764.1| 749|Homo sapiens 70 kD alpha-glucosidase
protein.
Length = 749
Score = 41.5 bits (93), Expect = 0.004
Identities = 35/148 (23%), Positives = 68/148 (45%), Gaps = 15/148 (10%)
Query: 204 RMIFNTNRGPLVASQNIWELTFWLTNESMYGLGE--IPLEKTTK----VLYNHN------ 251
R++ NT PL + +L+ L ++ + GL E PL +T L+N +
Sbjct: 26 RVLLNTTVAPLFFADQFLQLSTSLPSQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPG 85
Query: 252 GGISGI-PLIFA-KSGHSYHGILIEAVAPTVITIRKENQIVLRSITSLGVKLHLFVGPKP 309
+ G P A + G S HG+ + + ++ + RS + + +++F+GP+P
Sbjct: 86 ANLYGSHPFYLALEDGGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGI-LDVYIFLGPEP 144
Query: 310 ADIMRDVRNLLGVNKRMEYWMFGAHICR 337
+++ +++G YW G H+CR
Sbjct: 145 KSVVQQYLDVVGYPFMPPYWGLGFHLCR 172
>X63597-1|CAA45140.1| 1827|Homo sapiens prosucrose-isomaltase
protein.
Length = 1827
Score = 38.3 bits (85), Expect = 0.038
Identities = 34/161 (21%), Positives = 70/161 (43%), Gaps = 20/161 (12%)
Query: 195 LNVVVNSTERMIFNTNRGPLVASQNIWELTFWLTNESMYGLGE--------------IPL 240
+ V+ S + +F+T+ GPLV S +++ L ++ +YG+GE P+
Sbjct: 201 IQVIRKSNGKTLFDTSIGPLVYSDQYLQISARLPSDYIYGIGEQVHKRFRHDLSWKTWPI 260
Query: 241 EKTTKVLYNHNGGISGIPLIFA----KSGHSYHGILIEAVAPTVITIRKENQIVLRSITS 296
++ ++N + G F SG S+ L+ + A + + IV +T
Sbjct: 261 FTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSNAMEIFI--QPTPIVTYRVTG 318
Query: 297 LGVKLHLFVGPKPADIMRDVRNLLGVNKRMEYWMFGAHICR 337
+ ++ +G P +++ + L+G+ YW G + R
Sbjct: 319 GILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSR 359
Score = 31.5 bits (68), Expect = 4.4
Identities = 14/69 (20%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 269 HGILIEAVAPTVITIRKENQIVLRSITSLGVKLHLFVGPKPADIMRDVRNLLGVNKRMEY 328
HG+ + +T + + R++ + + ++F+GP P + ++G Y
Sbjct: 1163 HGVFLLNSNAMDVTFQPTPALTYRTVGGI-LDFYMFLGPTPQVATKQYHEVIGHPVMPAY 1221
Query: 329 WMFGAHICR 337
W G +CR
Sbjct: 1222 WALGFQLCR 1230
>M22616-1|AAA60551.1| 679|Homo sapiens SI protein.
Length = 679
Score = 38.3 bits (85), Expect = 0.038
Identities = 34/161 (21%), Positives = 70/161 (43%), Gaps = 20/161 (12%)
Query: 195 LNVVVNSTERMIFNTNRGPLVASQNIWELTFWLTNESMYGLGE--------------IPL 240
+ V+ S + +F+T+ GPLV S +++ L ++ +YG+GE P+
Sbjct: 201 IQVIRKSNGKTLFDTSIGPLVYSDQYLQISARLPSDYIYGIGEQVHKRFRHDLSWKTWPI 260
Query: 241 EKTTKVLYNHNGGISGIPLIFA----KSGHSYHGILIEAVAPTVITIRKENQIVLRSITS 296
++ ++N + G F SG S+ L+ + A + + IV +T
Sbjct: 261 FTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSNAMEIFI--QPTPIVTYRVTG 318
Query: 297 LGVKLHLFVGPKPADIMRDVRNLLGVNKRMEYWMFGAHICR 337
+ ++ +G P +++ + L+G+ YW G + R
Sbjct: 319 GILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSR 359
>BC132860-1|AAI32861.1| 1827|Homo sapiens sucrase-isomaltase
(alpha-glucosidase) protein.
Length = 1827
Score = 38.3 bits (85), Expect = 0.038
Identities = 34/161 (21%), Positives = 70/161 (43%), Gaps = 20/161 (12%)
Query: 195 LNVVVNSTERMIFNTNRGPLVASQNIWELTFWLTNESMYGLGE--------------IPL 240
+ V+ S + +F+T+ GPLV S +++ L ++ +YG+GE P+
Sbjct: 201 IQVIRKSNGKTLFDTSIGPLVYSDQYLQISTRLPSDYIYGIGEQVHKRFRHDLSWKTWPI 260
Query: 241 EKTTKVLYNHNGGISGIPLIFA----KSGHSYHGILIEAVAPTVITIRKENQIVLRSITS 296
++ ++N + G F SG S+ L+ + A + + IV +T
Sbjct: 261 FTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSNAMEIFI--QPTPIVTYRVTG 318
Query: 297 LGVKLHLFVGPKPADIMRDVRNLLGVNKRMEYWMFGAHICR 337
+ ++ +G P +++ + L+G+ YW G + R
Sbjct: 319 GILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSR 359
Score = 31.5 bits (68), Expect = 4.4
Identities = 14/69 (20%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 269 HGILIEAVAPTVITIRKENQIVLRSITSLGVKLHLFVGPKPADIMRDVRNLLGVNKRMEY 328
HG+ + +T + + R++ + + ++F+GP P + ++G Y
Sbjct: 1163 HGVFLLNSNAMDVTFQPTPALTYRTVGGI-LDFYMFLGPTPEVATKQYHEVIGHPVMPAY 1221
Query: 329 WMFGAHICR 337
W G +CR
Sbjct: 1222 WALGFQLCR 1230
>BC132834-1|AAI32835.1| 1827|Homo sapiens sucrase-isomaltase
(alpha-glucosidase) protein.
Length = 1827
Score = 38.3 bits (85), Expect = 0.038
Identities = 34/161 (21%), Positives = 70/161 (43%), Gaps = 20/161 (12%)
Query: 195 LNVVVNSTERMIFNTNRGPLVASQNIWELTFWLTNESMYGLGE--------------IPL 240
+ V+ S + +F+T+ GPLV S +++ L ++ +YG+GE P+
Sbjct: 201 IQVIRKSNGKTLFDTSIGPLVYSDQYLQISTRLPSDYIYGIGEQVHKRFRHDLSWKTWPI 260
Query: 241 EKTTKVLYNHNGGISGIPLIFA----KSGHSYHGILIEAVAPTVITIRKENQIVLRSITS 296
++ ++N + G F SG S+ L+ + A + + IV +T
Sbjct: 261 FTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSNAMEIFI--QPTPIVTYRVTG 318
Query: 297 LGVKLHLFVGPKPADIMRDVRNLLGVNKRMEYWMFGAHICR 337
+ ++ +G P +++ + L+G+ YW G + R
Sbjct: 319 GILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSR 359
Score = 31.5 bits (68), Expect = 4.4
Identities = 14/69 (20%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 269 HGILIEAVAPTVITIRKENQIVLRSITSLGVKLHLFVGPKPADIMRDVRNLLGVNKRMEY 328
HG+ + +T + + R++ + + ++F+GP P + ++G Y
Sbjct: 1163 HGVFLLNSNAMDVTFQPTPALTYRTVGGI-LDFYMFLGPTPEVATKQYHEVIGHPVMPAY 1221
Query: 329 WMFGAHICR 337
W G +CR
Sbjct: 1222 WALGFQLCR 1230
>BC116452-1|AAI16453.1| 1827|Homo sapiens sucrase-isomaltase
(alpha-glucosidase) protein.
Length = 1827
Score = 38.3 bits (85), Expect = 0.038
Identities = 34/161 (21%), Positives = 70/161 (43%), Gaps = 20/161 (12%)
Query: 195 LNVVVNSTERMIFNTNRGPLVASQNIWELTFWLTNESMYGLGE--------------IPL 240
+ V+ S + +F+T+ GPLV S +++ L ++ +YG+GE P+
Sbjct: 201 IQVIRKSNGKTLFDTSIGPLVYSDQYLQISARLPSDYIYGIGEQVHKRFRHDLSWKTWPI 260
Query: 241 EKTTKVLYNHNGGISGIPLIFA----KSGHSYHGILIEAVAPTVITIRKENQIVLRSITS 296
++ ++N + G F SG S+ L+ + A + + IV +T
Sbjct: 261 FTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSDAMEIFI--QPTPIVTYRVTG 318
Query: 297 LGVKLHLFVGPKPADIMRDVRNLLGVNKRMEYWMFGAHICR 337
+ ++ +G P +++ + L+G+ YW G + R
Sbjct: 319 GILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSR 359
Score = 31.5 bits (68), Expect = 4.4
Identities = 14/69 (20%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 269 HGILIEAVAPTVITIRKENQIVLRSITSLGVKLHLFVGPKPADIMRDVRNLLGVNKRMEY 328
HG+ + +T + + R++ + + ++F+GP P + ++G Y
Sbjct: 1163 HGVFLLNSNAMDVTFQPTPALTYRTVGGI-LDFYMFLGPTPEVATKQYHEVIGHPVMPAY 1221
Query: 329 WMFGAHICR 337
W G +CR
Sbjct: 1222 WALGFQLCR 1230
>BC115034-1|AAI15035.1| 1827|Homo sapiens sucrase-isomaltase
(alpha-glucosidase) protein.
Length = 1827
Score = 38.3 bits (85), Expect = 0.038
Identities = 34/161 (21%), Positives = 70/161 (43%), Gaps = 20/161 (12%)
Query: 195 LNVVVNSTERMIFNTNRGPLVASQNIWELTFWLTNESMYGLGE--------------IPL 240
+ V+ S + +F+T+ GPLV S +++ L ++ +YG+GE P+
Sbjct: 201 IQVIRKSNGKTLFDTSIGPLVYSDQYLQISARLPSDYIYGIGEQVHKRFRHDLSWKTWPI 260
Query: 241 EKTTKVLYNHNGGISGIPLIFA----KSGHSYHGILIEAVAPTVITIRKENQIVLRSITS 296
++ ++N + G F SG S+ L+ + A + + IV +T
Sbjct: 261 FTRDQLPGDNNNNLYGHQTFFMCIEDTSGKSFGVFLMNSNAMEIFI--QPTPIVTYRVTG 318
Query: 297 LGVKLHLFVGPKPADIMRDVRNLLGVNKRMEYWMFGAHICR 337
+ ++ +G P +++ + L+G+ YW G + R
Sbjct: 319 GILDFYILLGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSR 359
Score = 32.3 bits (70), Expect = 2.5
Identities = 15/79 (18%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Query: 259 LIFAKSGHSYHGILIEAVAPTVITIRKENQIVLRSITSLGVKLHLFVGPKPADIMRDVRN 318
++ + G++ HG+ + +T + + R++ + + ++F+GP P +
Sbjct: 1154 MVLEEEGNA-HGVFLLNSNAMDVTFQPTPALTYRTVGGI-LDFYMFLGPTPEVATKQYHE 1211
Query: 319 LLGVNKRMEYWMFGAHICR 337
++G YW G +CR
Sbjct: 1212 VIGHPVMPAYWALGFQLCR 1230
>BC111975-1|AAI11976.1| 482|Homo sapiens maltase-glucoamylase-like
protein.
Length = 482
Score = 38.3 bits (85), Expect = 0.038
Identities = 40/173 (23%), Positives = 78/173 (45%), Gaps = 22/173 (12%)
Query: 185 NYFYDVASPELNVVV--NSTERMIFNTNRGPLVASQNIWELTFWLTNESMYGLGEIPLE- 241
+Y+ +V ++ + S R++ +T+ GPL +Q +L+F L + ++YGLGE +
Sbjct: 169 SYYVEVTDKPFSIKIMRTSNRRVLLDTSIGPLQFAQQYLQLSFRLPSANVYGLGEHVHQQ 228
Query: 242 -------KT----------TKVLYNHNGGISGIPLIFAKSGHSYHGILIEAVAPTVITIR 284
KT T+ + N G + + G S+ L+ + A V T++
Sbjct: 229 YRHNMTWKTWPIFTRDATPTEGMINLYGAHTFFLCLEDARGSSFGVFLMNSNAMEV-TLQ 287
Query: 285 KENQIVLRSITSLGVKLHLFVGPKPADIMRDVRNLLGVNKRMEYWMFGAHICR 337
I R+I + + ++F+G P ++++ L+G YW G + R
Sbjct: 288 PAPAITYRTIGGI-LDFYVFLGNTPEQVVQEYLELVGRPFLPPYWSLGFQLSR 339
>BC111973-1|AAI11974.1| 482|Homo sapiens maltase-glucoamylase-like
protein.
Length = 482
Score = 38.3 bits (85), Expect = 0.038
Identities = 40/173 (23%), Positives = 78/173 (45%), Gaps = 22/173 (12%)
Query: 185 NYFYDVASPELNVVV--NSTERMIFNTNRGPLVASQNIWELTFWLTNESMYGLGEIPLE- 241
+Y+ +V ++ + S R++ +T+ GPL +Q +L+F L + ++YGLGE +
Sbjct: 169 SYYVEVTDKPFSIKIMRTSNRRVLLDTSIGPLQFAQQYLQLSFRLPSANVYGLGEHVHQQ 228
Query: 242 -------KT----------TKVLYNHNGGISGIPLIFAKSGHSYHGILIEAVAPTVITIR 284
KT T+ + N G + + G S+ L+ + A V T++
Sbjct: 229 YRHNMTWKTWPIFTRDATPTEGMINLYGAHTFFLCLEDARGSSFGVFLMNSNAMEV-TLQ 287
Query: 285 KENQIVLRSITSLGVKLHLFVGPKPADIMRDVRNLLGVNKRMEYWMFGAHICR 337
I R+I + + ++F+G P ++++ L+G YW G + R
Sbjct: 288 PAPAITYRTIGGI-LDFYVFLGNTPEQVVQEYLELVGRPFLPPYWSLGFQLSR 339
>AC073647-1|AAS07445.1| 327|Homo sapiens unknown protein.
Length = 327
Score = 36.7 bits (81), Expect = 0.12
Identities = 28/117 (23%), Positives = 57/117 (48%), Gaps = 13/117 (11%)
Query: 134 SARVATIPFS--FQNSLPRIKLSIDEVSKS--HLSLNFYNPALVEIPH-------GNRLE 182
+AR+ +P S F +++ + L+ + + + H L E+PH GN
Sbjct: 152 TARLKNLPSSPVFGSNVDNVLLTAEYQTSNRFHFKLTDQTNNRFEVPHEHVQSFSGNAAA 211
Query: 183 EKNYFYDVASPELNVVVN--STERMIFNTNRGPLVASQNIWELTFWLTNESMYGLGE 237
Y +++ ++ V S R++F+++ GPL+ + +L+ L + ++YGLGE
Sbjct: 212 SLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLLFADQFLQLSTRLPSTNVYGLGE 268
>U25657-1|AAA83628.1| 80|Homo sapiens intestinal trefoil factor
protein.
Length = 80
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 72 GFSFGSCLVARTLRLPCGYANVNSEQCHPH-CCYDFR 107
G S C V R+ CGY +V ++C+ CC+D R
Sbjct: 26 GLSANQCAVPAKDRVDCGYPHVTPKECNNRGCCFDSR 62
>L15203-1|AAA59981.1| 80|Homo sapiens secretory protein protein.
Length = 80
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 72 GFSFGSCLVARTLRLPCGYANVNSEQCHPH-CCYDFR 107
G S C V R+ CGY +V ++C+ CC+D R
Sbjct: 26 GLSANQCAVPAKDRVDCGYPHVTPKECNNRGCCFDSR 62
>L08044-1|AAA36766.1| 74|Homo sapiens intestinal trefoil factor
protein.
Length = 74
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 72 GFSFGSCLVARTLRLPCGYANVNSEQCHPH-CCYDFR 107
G S C V R+ CGY +V ++C+ CC+D R
Sbjct: 19 GLSANQCAVPAKDRVDCGYPHVTPKECNNRGCCFDSR 55
>BC017859-1|AAH17859.1| 73|Homo sapiens TFF3 protein protein.
Length = 73
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 72 GFSFGSCLVARTLRLPCGYANVNSEQCHPH-CCYDFR 107
G S C V R+ CGY +V ++C+ CC+D R
Sbjct: 19 GLSANQCAVPAKDRVDCGYPHVTPKECNNRGCCFDSR 55
>AP001746-2|BAA95531.1| 73|Homo sapiens trefoil factor 3, HITF,
human intestinal trefoil factor protein.
Length = 73
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 72 GFSFGSCLVARTLRLPCGYANVNSEQCHPH-CCYDFR 107
G S C V R+ CGY +V ++C+ CC+D R
Sbjct: 19 GLSANQCAVPAKDRVDCGYPHVTPKECNNRGCCFDSR 55
>AB038162-3|BAB13731.1| 73|Homo sapiens trefoil factor 3 protein.
Length = 73
Score = 33.5 bits (73), Expect = 1.1
Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 72 GFSFGSCLVARTLRLPCGYANVNSEQCHPH-CCYDFR 107
G S C V R+ CGY +V ++C+ CC+D R
Sbjct: 19 GLSANQCAVPAKDRVDCGYPHVTPKECNNRGCCFDSR 55
>AK131337-1|BAD18495.1| 646|Homo sapiens protein ( Homo sapiens
cDNA FLJ16351 fis, clone TESTI2039060, moderately
similar to Maltase-glucoamylase, intestinal. ).
Length = 646
Score = 32.7 bits (71), Expect = 1.9
Identities = 16/71 (22%), Positives = 33/71 (46%), Gaps = 1/71 (1%)
Query: 267 SYHGILIEAVAPTVITIRKENQIVLRSITSLGVKLHLFVGPKPADIMRDVRNLLGVNKRM 326
S HG+L+ +T++ + R+ + + ++ +GP P + + L+G +
Sbjct: 64 SAHGVLLLNSNAMDVTLQPTPALTYRTTGGI-LDFYIVLGPTPELVTQQYTELIGRPAMI 122
Query: 327 EYWMFGAHICR 337
YW G H+ R
Sbjct: 123 PYWALGFHLSR 133
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.323 0.139 0.436
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 49,044,812
Number of Sequences: 224733
Number of extensions: 1868152
Number of successful extensions: 6064
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 6021
Number of HSP's gapped (non-prelim): 44
length of query: 337
length of database: 73,234,838
effective HSP length: 90
effective length of query: 247
effective length of database: 53,008,868
effective search space: 13093190396
effective search space used: 13093190396
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (22.0 bits)
S2: 66 (30.7 bits)
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