Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001560-TA|BGIBMGA001560-PA|IPR000980|SH2 motif,
IPR001452|Src homology-3, IPR001849|Pleckstrin-like, IPR001936|Ras
GTPase-activating protein, IPR000008|C2 calcium-dependent membrane
targeting, IPR008936|Rho GTPase activation protein, IPR008973|C2
calcium/lipid-binding region, CaLB
(932 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q8IR23 Cluster: CG9209-PA, isoform A; n=6; Endopterygot... 1271 0.0
UniRef50_P20936 Cluster: Ras GTPase-activating protein 1; n=50; ... 725 0.0
UniRef50_UPI00015B62FA Cluster: PREDICTED: similar to ras gtpase... 665 0.0
UniRef50_UPI0000E49CFC Cluster: PREDICTED: similar to Ras GTPase... 495 e-138
UniRef50_A7SJB4 Cluster: Predicted protein; n=1; Nematostella ve... 482 e-134
UniRef50_Q4RUN4 Cluster: Chromosome 12 SCAF14993, whole genome s... 412 e-113
UniRef50_UPI0000E4852D Cluster: PREDICTED: similar to Ras GTPase... 252 3e-65
UniRef50_Q54Y08 Cluster: NGAP-like protein; n=1; Dictyostelium d... 196 3e-48
UniRef50_Q8MLZ5 Cluster: Ras GTPase-activating protein gap-2; n=... 162 3e-38
UniRef50_Q5VWQ8 Cluster: Disabled homolog 2-interacting protein;... 161 1e-37
UniRef50_Q55CR5 Cluster: Putative uncharacterized protein; n=1; ... 158 6e-37
UniRef50_Q4TC99 Cluster: Chromosome undetermined SCAF7039, whole... 151 1e-34
UniRef50_UPI0000F1E1DA Cluster: PREDICTED: hypothetical protein;... 149 3e-34
UniRef50_Q54RT3 Cluster: Putative uncharacterized protein; n=1; ... 142 3e-32
UniRef50_UPI0000DB6EB0 Cluster: PREDICTED: similar to CG32560-PA... 141 7e-32
UniRef50_O95294 Cluster: RasGAP-activating-like protein 1; n=25;... 140 1e-31
UniRef50_UPI00015B5738 Cluster: PREDICTED: similar to synaptic r... 138 6e-31
UniRef50_Q14644 Cluster: Ras GTPase-activating protein 3 (GAP1(I... 138 8e-31
UniRef50_Q96PV0 Cluster: Ras GTPase-activating protein SynGAP; n... 136 2e-30
UniRef50_A7RYE3 Cluster: Predicted protein; n=1; Nematostella ve... 136 3e-30
UniRef50_A7SKG2 Cluster: Predicted protein; n=1; Nematostella ve... 135 6e-30
UniRef50_Q8WZX6 Cluster: Related to NEUROFIBROMIN; n=4; Sordario... 135 6e-30
UniRef50_A6R6N8 Cluster: Predicted protein; n=1; Ajellomyces cap... 134 1e-29
UniRef50_Q9P412 Cluster: GTPase activating protein; n=1; Blumeri... 131 1e-28
UniRef50_A2QLJ8 Cluster: Contig An06c0090, complete genome; n=1;... 131 1e-28
UniRef50_A1CU76 Cluster: GTPase activating protein (BUD2/CLA2), ... 131 1e-28
UniRef50_UPI000156148A Cluster: PREDICTED: hypothetical protein;... 129 3e-28
UniRef50_A4RD11 Cluster: Putative uncharacterized protein; n=1; ... 126 2e-27
UniRef50_Q178K3 Cluster: Synaptic ras gtpase activating protein,... 124 1e-26
UniRef50_Q15283 Cluster: Ras GTPase-activating protein 2; n=14; ... 123 2e-26
UniRef50_Q54Q13 Cluster: Putative uncharacterized protein; n=1; ... 122 3e-26
UniRef50_UPI0000DB7F93 Cluster: PREDICTED: similar to RAS p21 pr... 121 8e-26
UniRef50_Q8T498 Cluster: Probable Ras GTPase-activating protein;... 121 1e-25
UniRef50_A4RH06 Cluster: Putative uncharacterized protein; n=2; ... 120 2e-25
UniRef50_Q2GTK6 Cluster: Putative uncharacterized protein; n=1; ... 119 4e-25
UniRef50_Q52KF5 Cluster: Dab2ip protein; n=13; Euteleostomi|Rep:... 118 7e-25
UniRef50_P48423 Cluster: GTPase-activating protein; n=4; Sophoph... 117 2e-24
UniRef50_A7EI47 Cluster: Putative uncharacterized protein; n=1; ... 116 3e-24
UniRef50_A6SKM1 Cluster: Putative uncharacterized protein; n=1; ... 115 5e-24
UniRef50_A7F7G1 Cluster: Putative uncharacterized protein; n=1; ... 114 9e-24
UniRef50_Q0URT8 Cluster: Putative uncharacterized protein; n=1; ... 113 2e-23
UniRef50_Q4SHY4 Cluster: Chromosome 5 SCAF14581, whole genome sh... 112 5e-23
UniRef50_Q7RW81 Cluster: Putative uncharacterized protein NCU038... 111 1e-22
UniRef50_Q8SSU4 Cluster: Similar to Dictyostelium discoideum (Sl... 110 2e-22
UniRef50_Q6C802 Cluster: Yarrowia lipolytica chromosome D of str... 110 2e-22
UniRef50_A2CE77 Cluster: Novel protein similar to vertebrate RAS... 106 2e-21
UniRef50_O43374 Cluster: Ras GTPase-activating protein 4; n=65; ... 105 4e-21
UniRef50_Q7PTK8 Cluster: ENSANGP00000021695; n=2; Culicidae|Rep:... 103 2e-20
UniRef50_Q6CW67 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 103 2e-20
UniRef50_Q54T13 Cluster: Putative uncharacterized protein; n=1; ... 101 1e-19
UniRef50_Q5KFG6 Cluster: Ras GTPase activator, putative; n=2; Fi... 100 2e-19
UniRef50_O01398 Cluster: Neurofibromin; n=12; cellular organisms... 100 2e-19
UniRef50_UPI000049A55D Cluster: Ras GTPase activating protein; n... 100 4e-19
UniRef50_UPI0000499EEB Cluster: Ras GTPase activating protein; n... 97 3e-18
UniRef50_UPI000066100B Cluster: Ras GTPase-activating protein nG... 95 8e-18
UniRef50_UPI000049A289 Cluster: Ras GTPase activating protein; n... 95 1e-17
UniRef50_UPI0000ECAA02 Cluster: RasGAP-activating-like protein 1... 94 1e-17
UniRef50_Q4PF31 Cluster: Putative uncharacterized protein; n=1; ... 93 3e-17
UniRef50_Q22720 Cluster: Ras GTPase-activating protein gap-1; n=... 92 7e-17
UniRef50_A2R7H8 Cluster: Function: sar1 of S. pombe encodes a pr... 91 1e-16
UniRef50_Q5C1M0 Cluster: SJCHGC08700 protein; n=1; Schistosoma j... 88 1e-15
UniRef50_Q0UYR2 Cluster: Putative uncharacterized protein; n=1; ... 88 1e-15
UniRef50_Q54I64 Cluster: RasGTPase-activating protein; n=1; Dict... 87 2e-15
UniRef50_Q4T1K3 Cluster: Chromosome 16 SCAF10562, whole genome s... 85 1e-14
UniRef50_P21359 Cluster: Neurofibromin (Neurofibromatosis-relate... 83 3e-14
UniRef50_Q75DK0 Cluster: ABR021Wp; n=1; Eremothecium gossypii|Re... 83 3e-14
UniRef50_P33314 Cluster: Inhibitory regulator protein BUD2/CLA2;... 83 4e-14
UniRef50_UPI0000E460AA Cluster: PREDICTED: similar to GAP-relate... 82 6e-14
UniRef50_A7TTA0 Cluster: Putative uncharacterized protein; n=1; ... 81 1e-13
UniRef50_Q6CMT2 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 81 2e-13
UniRef50_UPI000049A418 Cluster: Ras GTPase activating protein; n... 80 2e-13
UniRef50_A7S5U4 Cluster: Predicted protein; n=1; Nematostella ve... 80 2e-13
UniRef50_Q6FNM9 Cluster: Candida glabrata strain CBS138 chromoso... 80 2e-13
UniRef50_A5E1X9 Cluster: Putative uncharacterized protein; n=1; ... 80 3e-13
UniRef50_Q55AR6 Cluster: Putative uncharacterized protein; n=2; ... 78 1e-12
UniRef50_P19158 Cluster: Inhibitory regulator protein IRA2; n=2;... 77 2e-12
UniRef50_A7TN87 Cluster: Putative uncharacterized protein; n=1; ... 77 2e-12
UniRef50_Q757I8 Cluster: AER025Cp; n=2; Eukaryota|Rep: AER025Cp ... 73 3e-11
UniRef50_A3GHY3 Cluster: Ras GTPase activating protein RasGAP/ne... 73 3e-11
UniRef50_Q4V9Q1 Cluster: Zgc:109892; n=11; Euteleostomi|Rep: Zgc... 70 3e-10
UniRef50_P18963 Cluster: Inhibitory regulator protein IRA1; n=2;... 70 3e-10
UniRef50_Q6FJ13 Cluster: Candida glabrata strain CBS138 chromoso... 69 4e-10
UniRef50_Q5A3W3 Cluster: Putative uncharacterized protein IRA2; ... 69 4e-10
UniRef50_Q5F3D9 Cluster: Putative uncharacterized protein; n=2; ... 69 8e-10
UniRef50_UPI0000498B16 Cluster: Ras GTPase activating protein; n... 68 1e-09
UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2;... 66 3e-09
UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2;... 66 3e-09
UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to protein-ty... 66 4e-09
UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6; En... 66 4e-09
UniRef50_UPI000058445F Cluster: PREDICTED: similar to SH2/SH3 ad... 66 5e-09
UniRef50_A3LZE1 Cluster: GTPase-activating protein; n=3; Sacchar... 65 7e-09
UniRef50_UPI00015A7910 Cluster: hypothetical protein LOC553596; ... 65 1e-08
UniRef50_Q9VXH3 Cluster: CG4200-PA; n=5; Drosophila|Rep: CG4200-... 65 1e-08
UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21; Bil... 65 1e-08
UniRef50_Q6PE32 Cluster: Zgc:65942; n=2; Danio rerio|Rep: Zgc:65... 64 1e-08
UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monos... 64 2e-08
UniRef50_A7SCW1 Cluster: Predicted protein; n=1; Nematostella ve... 64 2e-08
UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1; n... 64 2e-08
UniRef50_Q4SAX0 Cluster: Chromosome 3 SCAF14679, whole genome sh... 64 2e-08
UniRef50_Q5A506 Cluster: Putative uncharacterized protein BUD2; ... 64 2e-08
UniRef50_UPI00004997E1 Cluster: hypothetical protein 291.t00003;... 63 3e-08
UniRef50_UPI00015A79D6 Cluster: hypothetical protein LOC550452; ... 62 5e-08
UniRef50_Q567F1 Cluster: Zgc:112091; n=2; Euteleostomi|Rep: Zgc:... 62 5e-08
UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa g... 62 5e-08
UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-prote... 62 5e-08
UniRef50_O15815 Cluster: RasGTPase-activating protein; n=3; Dict... 62 7e-08
UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-recept... 61 1e-07
UniRef50_Q6FQA1 Cluster: Candida glabrata strain CBS138 chromoso... 60 2e-07
UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3; ... 60 3e-07
UniRef50_A7TEG6 Cluster: Putative uncharacterized protein; n=1; ... 60 3e-07
UniRef50_Q9UN19 Cluster: Dual adapter for phosphotyrosine and 3-... 60 3e-07
UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew;... 60 3e-07
UniRef50_O75791 Cluster: GRB2-related adapter protein 2; n=22; A... 59 5e-07
UniRef50_Q9XYM0 Cluster: Adapter molecule Crk; n=7; Endopterygot... 59 5e-07
UniRef50_UPI0000F2C9B7 Cluster: PREDICTED: similar to FLJ00412 p... 59 6e-07
UniRef50_Q4T1V0 Cluster: Chromosome undetermined SCAF10467, whol... 58 8e-07
UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome s... 58 8e-07
UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to Tyrosine-p... 58 1e-06
UniRef50_UPI00004989A6 Cluster: Ras GTPase activating protein; n... 58 1e-06
UniRef50_UPI0000660CF8 Cluster: Crk-like protein.; n=3; Euteleos... 58 1e-06
UniRef50_Q4RNX3 Cluster: Chromosome 10 SCAF15009, whole genome s... 58 1e-06
UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep:... 58 1e-06
UniRef50_Q0PIN0 Cluster: Bam32; n=1; Branchiostoma belcheri tsin... 58 1e-06
UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase ... 58 1e-06
UniRef50_UPI0000E478D2 Cluster: PREDICTED: similar to SH2/SH3 ad... 57 2e-06
UniRef50_UPI00015A4B5A Cluster: protein tyrosine phosphatase, no... 57 2e-06
UniRef50_P19174 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 57 2e-06
UniRef50_UPI0000D57912 Cluster: PREDICTED: similar to CG4200-PA;... 56 3e-06
UniRef50_Q7QHE3 Cluster: ENSANGP00000022029; n=2; Anopheles gamb... 56 3e-06
UniRef50_O00899 Cluster: GAPA; n=2; Dictyostelium discoideum|Rep... 56 3e-06
UniRef50_UPI0000E460CB Cluster: PREDICTED: similar to V-crk sarc... 56 4e-06
UniRef50_Q95PW9 Cluster: Temporarily assigned gene name protein ... 56 4e-06
UniRef50_O97034 Cluster: PLC-gammaS; n=1; Ephydatia fluviatilis|... 56 4e-06
UniRef50_A7SXE3 Cluster: Predicted protein; n=1; Nematostella ve... 56 4e-06
UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|R... 56 4e-06
UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome sh... 55 8e-06
UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hyd... 55 8e-06
UniRef50_UPI0000E49A1C Cluster: PREDICTED: similar to Growth fac... 55 1e-05
UniRef50_Q4T6N5 Cluster: Chromosome 9 SCAF8684, whole genome sho... 55 1e-05
UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92... 54 1e-05
UniRef50_A6SJZ0 Cluster: Putative uncharacterized protein; n=1; ... 54 1e-05
UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-recept... 54 1e-05
UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21; Deut... 54 1e-05
UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54; Gnat... 54 1e-05
UniRef50_Q4RP74 Cluster: Chromosome 1 SCAF15008, whole genome sh... 54 2e-05
UniRef50_Q4P2J5 Cluster: Putative uncharacterized protein; n=1; ... 54 2e-05
UniRef50_A5DHJ9 Cluster: Putative uncharacterized protein; n=1; ... 54 2e-05
UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54; Euteleo... 54 2e-05
UniRef50_P33277 Cluster: GTPase-activating protein; n=1; Schizos... 54 2e-05
UniRef50_Q4T2Z8 Cluster: Chromosome 18 SCAF10147, whole genome s... 54 2e-05
UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; H... 54 2e-05
UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27; Fung... 54 2e-05
UniRef50_Q4SS18 Cluster: Chromosome undetermined SCAF14482, whol... 53 4e-05
UniRef50_A2RQD6 Cluster: Bcr-abl1 e6a2 chimeric protein; n=10; E... 53 4e-05
UniRef50_A2RQD3 Cluster: Bcr-abl1 e13a3 chimeric protein; n=21; ... 53 4e-05
UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming pr... 53 4e-05
UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase ... 53 4e-05
UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to protein-ty... 52 5e-05
UniRef50_UPI0000498DA6 Cluster: hypothetical protein 6.t00064; n... 52 5e-05
UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 52 5e-05
UniRef50_A2FB27 Cluster: GTPase-activator protein, putative; n=1... 52 5e-05
UniRef50_Q6CFR5 Cluster: Yarrowia lipolytica chromosome B of str... 52 5e-05
UniRef50_P43405 Cluster: Tyrosine-protein kinase SYK; n=23; Ther... 52 5e-05
UniRef50_UPI00015B564A Cluster: PREDICTED: similar to CRK protei... 52 7e-05
UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2; C... 52 7e-05
UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma m... 52 7e-05
UniRef50_P05433 Cluster: P47(GAG-CRK) protein; n=3; root|Rep: P4... 52 7e-05
UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming pr... 52 7e-05
UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to proto-onco... 52 1e-04
UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN full-le... 52 1e-04
UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole... 51 1e-04
UniRef50_Q7QG48 Cluster: ENSANGP00000010943; n=1; Anopheles gamb... 51 1e-04
UniRef50_Q5DBN4 Cluster: SJCHGC05332 protein; n=1; Schistosoma j... 51 1e-04
UniRef50_UPI00015B636F Cluster: PREDICTED: similar to IQ motif c... 51 2e-04
UniRef50_Q98TP5 Cluster: C-Src protein-tyrosine kinase; n=5; Eut... 51 2e-04
UniRef50_Q7T0U4 Cluster: MGC68984 protein; n=2; Xenopus|Rep: MGC... 50 2e-04
UniRef50_Q1KL02 Cluster: Chimerin 2; n=3; Tetraodontidae|Rep: Ch... 50 2e-04
UniRef50_Q15464 Cluster: SH2 domain-containing adapter protein B... 50 2e-04
UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38; Eut... 50 2e-04
UniRef50_UPI0000F1D8DB Cluster: PREDICTED: hypothetical protein;... 50 3e-04
UniRef50_Q6DEM2 Cluster: V-crk sarcoma virus CT10 oncogene homol... 50 3e-04
UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9; Endopterygot... 50 3e-04
UniRef50_Q5BWZ4 Cluster: SJCHGC04657 protein; n=1; Schistosoma j... 50 3e-04
UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella ve... 50 3e-04
UniRef50_Q0V6E4 Cluster: Putative uncharacterized protein; n=1; ... 50 3e-04
UniRef50_O15357 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 50 4e-04
UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5; Eutel... 50 4e-04
UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA... 49 5e-04
UniRef50_UPI000051A29D Cluster: PREDICTED: similar to SHC-adapto... 49 5e-04
UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase ... 49 5e-04
UniRef50_P08631 Cluster: Tyrosine-protein kinase HCK; n=32; Eute... 49 5e-04
UniRef50_UPI0000E46C42 Cluster: PREDICTED: similar to Grb14; n=2... 49 7e-04
UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio "Ph... 49 7e-04
UniRef50_Q7M4L6 Cluster: Shb-like adapter protein, Shf; n=21; Am... 49 7e-04
UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11; Mammal... 49 7e-04
UniRef50_UPI0000F1F923 Cluster: PREDICTED: similar to SH2 domain... 48 9e-04
UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whol... 48 9e-04
UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome sh... 48 9e-04
UniRef50_Q8WPV5 Cluster: Tyrosine kinase; n=2; Eumetazoa|Rep: Ty... 48 9e-04
UniRef50_Q13576 Cluster: Ras GTPase-activating-like protein IQGA... 48 9e-04
UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosi... 48 0.001
UniRef50_UPI000069F318 Cluster: UPI000069F318 related cluster; n... 48 0.001
UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2; Culicidae... 48 0.001
UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17; Amn... 48 0.001
UniRef50_Q9H788 Cluster: SH2 domain-containing protein 4A (Prote... 48 0.001
UniRef50_UPI0000E48B80 Cluster: PREDICTED: hypothetical protein;... 48 0.002
UniRef50_UPI00004995F7 Cluster: Ras GTPase activating protein; n... 48 0.002
UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP099... 48 0.002
UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase ... 48 0.002
UniRef50_O14492 Cluster: SH2B adapter protein 2; n=7; Tetrapoda|... 48 0.002
UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5; Eumet... 48 0.002
UniRef50_A2AQ87 Cluster: Novel protein (Possible orthologue of h... 47 0.002
UniRef50_Q22070 Cluster: Putative uncharacterized protein plc-3;... 47 0.002
UniRef50_Q9UKW4 Cluster: Protein vav-3; n=96; Euteleostomi|Rep: ... 47 0.002
UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2; Sop... 47 0.002
UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hyd... 47 0.002
UniRef50_Q1ED32 Cluster: Zgc:136231; n=1; Danio rerio|Rep: Zgc:1... 47 0.003
UniRef50_Q9TYT3 Cluster: Putative uncharacterized protein; n=5; ... 47 0.003
UniRef50_UPI00015B496D Cluster: PREDICTED: similar to conserved ... 46 0.004
UniRef50_UPI0000DB713D Cluster: PREDICTED: similar to CG11146-PA... 46 0.004
UniRef50_A1L2D2 Cluster: Zgc:158798; n=7; Clupeocephala|Rep: Zgc... 46 0.004
UniRef50_Q9VYM1 Cluster: CG11146-PA; n=2; Coelomata|Rep: CG11146... 46 0.004
UniRef50_Q9BI25 Cluster: SHK1 protein; n=2; Dictyostelium discoi... 46 0.004
UniRef50_Q965N4 Cluster: Putative uncharacterized protein; n=3; ... 46 0.004
UniRef50_A7RR81 Cluster: Predicted protein; n=1; Nematostella ve... 46 0.004
UniRef50_UPI0000D9EE2E Cluster: PREDICTED: similar to src homolo... 46 0.005
UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 46 0.005
UniRef50_Q13239 Cluster: SRC-like-adapter; n=26; Euteleostomi|Re... 46 0.005
UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein ty... 46 0.006
UniRef50_Q95XA9 Cluster: Putative uncharacterized protein; n=2; ... 46 0.006
UniRef50_Q6CFF4 Cluster: Yarrowia lipolytica chromosome B of str... 46 0.006
UniRef50_Q2I6J0 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 46 0.006
UniRef50_Q56A36 Cluster: Hematopoietic SH2 domain-containing pro... 46 0.006
UniRef50_UPI000065F097 Cluster: Hematopoietic SH2 domain-contain... 45 0.008
UniRef50_Q8T6F8 Cluster: SRC-1; n=3; Caenorhabditis|Rep: SRC-1 -... 45 0.008
UniRef50_P42687 Cluster: Tyrosine-protein kinase SPK-1; n=1; Gir... 45 0.008
UniRef50_P08630 Cluster: Tyrosine-protein kinase Btk29A; n=10; E... 45 0.008
UniRef50_UPI0000DB7727 Cluster: PREDICTED: similar to Tensin-1; ... 45 0.011
UniRef50_Q3ZB94 Cluster: Zgc:113360; n=3; Clupeocephala|Rep: Zgc... 45 0.011
UniRef50_Q1LX18 Cluster: Novel protein similar to vertebrate src... 45 0.011
UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep: Zgc:1... 45 0.011
UniRef50_Q6MGD1 Cluster: Synaptic Ras GTPase activating protein;... 45 0.011
UniRef50_Q7K137 Cluster: LD10453p; n=4; Diptera|Rep: LD10453p - ... 45 0.011
UniRef50_O88890 Cluster: SH2 domain-containing protein 1A; n=8; ... 45 0.011
UniRef50_UPI000155BC71 Cluster: PREDICTED: similar to inositol p... 44 0.014
UniRef50_UPI0000D8C686 Cluster: Breast cancer anti-estrogen resi... 44 0.014
UniRef50_O60880 Cluster: SH2 domain-containing protein 1A; n=18;... 44 0.014
UniRef50_Q14847 Cluster: LIM and SH3 domain protein 1; n=44; Eut... 44 0.014
UniRef50_UPI0000F2E785 Cluster: PREDICTED: hypothetical protein;... 44 0.019
UniRef50_UPI0000F201D0 Cluster: PREDICTED: hypothetical protein;... 44 0.019
UniRef50_UPI0000F1FB23 Cluster: PREDICTED: similar to tyrosine p... 44 0.019
UniRef50_Q4S6Q5 Cluster: Chromosome undetermined SCAF14724, whol... 44 0.019
UniRef50_Q4RQV0 Cluster: Chromosome 2 SCAF15004, whole genome sh... 44 0.019
UniRef50_Q5BXT3 Cluster: SJCHGC03955 protein; n=1; Schistosoma j... 44 0.019
UniRef50_Q92529 Cluster: SHC-transforming protein 3; n=34; Eutel... 44 0.019
UniRef50_Q9D7V1 Cluster: SH2 domain-containing protein 4A; n=4; ... 44 0.019
UniRef50_UPI0000E4625F Cluster: PREDICTED: hypothetical protein;... 44 0.025
UniRef50_UPI0000D554A0 Cluster: PREDICTED: similar to CG11146-PA... 44 0.025
UniRef50_UPI0000519A8B Cluster: PREDICTED: similar to Phosphatid... 44 0.025
UniRef50_Q86F73 Cluster: Clone ZZD1053 mRNA sequence; n=1; Schis... 44 0.025
UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2; Cul... 44 0.025
UniRef50_Q4P4C4 Cluster: Putative uncharacterized protein; n=1; ... 44 0.025
UniRef50_P42680 Cluster: Tyrosine-protein kinase Tec; n=86; Coel... 44 0.025
UniRef50_Q96IW2 Cluster: SH2 domain-containing adapter protein D... 44 0.025
UniRef50_P98077 Cluster: SHC-transforming protein 2; n=15; Tetra... 44 0.025
UniRef50_P52757 Cluster: Beta-chimaerin; n=13; Amniota|Rep: Beta... 44 0.025
UniRef50_UPI000065DBBA Cluster: Nebulin.; n=1; Takifugu rubripes... 43 0.033
UniRef50_Q910A2 Cluster: Spleen protein tyrosine kinase; n=2; Da... 43 0.033
UniRef50_Q4S131 Cluster: Chromosome 1 SCAF14770, whole genome sh... 43 0.033
UniRef50_Q5T185 Cluster: SHC (Src homology 2 domain containing) ... 43 0.033
UniRef50_Q2HFZ4 Cluster: Putative uncharacterized protein; n=1; ... 43 0.033
UniRef50_Q5VZ18 Cluster: SH2 domain-containing adapter protein E... 43 0.033
UniRef50_P29353 Cluster: SHC-transforming protein 1; n=46; Tetra... 43 0.033
UniRef50_Q9YGC1 Cluster: B-cell linker protein; n=10; Amniota|Re... 43 0.033
UniRef50_O75815 Cluster: Breast cancer anti-estrogen resistance ... 43 0.033
UniRef50_UPI00015B5375 Cluster: PREDICTED: similar to tensin; n=... 43 0.044
UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 43 0.044
UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CS... 43 0.044
UniRef50_A2DMS2 Cluster: GTPase-activator protein, putative; n=1... 43 0.044
UniRef50_P43403 Cluster: Tyrosine-protein kinase ZAP-70; n=55; E... 43 0.044
UniRef50_Q9VMJ4 Cluster: CG9098-PA, isoform A; n=5; Diptera|Rep:... 42 0.058
UniRef50_Q7QAK4 Cluster: ENSANGP00000020257; n=1; Anopheles gamb... 42 0.058
UniRef50_P46940 Cluster: Ras GTPase-activating-like protein IQGA... 42 0.058
UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5; Cae... 42 0.058
UniRef50_UPI000065FE19 Cluster: SHC-transforming protein 1 (SH2 ... 42 0.077
UniRef50_Q4RUJ0 Cluster: Chromosome 1 SCAF14995, whole genome sh... 42 0.077
UniRef50_Q9V3C8 Cluster: CG3715-PA; n=7; Endopterygota|Rep: CG37... 42 0.077
UniRef50_Q5BYR6 Cluster: SJCHGC04559 protein; n=1; Schistosoma j... 42 0.077
UniRef50_Q92835 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 42 0.077
UniRef50_UPI0000D555ED Cluster: PREDICTED: similar to CG32406-PA... 42 0.10
UniRef50_UPI00015A3F46 Cluster: UPI00015A3F46 related cluster; n... 42 0.10
UniRef50_Q4SH79 Cluster: Chromosome 8 SCAF14587, whole genome sh... 42 0.10
UniRef50_Q4RL31 Cluster: Chromosome undetermined SCAF15024, whol... 42 0.10
UniRef50_Q7QGU0 Cluster: ENSANGP00000018199; n=1; Anopheles gamb... 42 0.10
UniRef50_A6R4D6 Cluster: Putative uncharacterized protein; n=1; ... 42 0.10
UniRef50_Q8IZW8 Cluster: Tensin-4 precursor; n=17; Eutheria|Rep:... 42 0.10
UniRef50_UPI00015B5EF2 Cluster: PREDICTED: similar to ENSANGP000... 41 0.13
UniRef50_UPI0000E811F8 Cluster: PREDICTED: similar to SH2D3C pro... 41 0.13
UniRef50_UPI000058412C Cluster: PREDICTED: hypothetical protein;... 41 0.13
UniRef50_Q4SXJ3 Cluster: Chromosome 3 SCAF12383, whole genome sh... 41 0.13
UniRef50_Q4SM05 Cluster: Chromosome 13 SCAF14555, whole genome s... 41 0.13
UniRef50_Q4RNL0 Cluster: Chromosome 21 SCAF15012, whole genome s... 41 0.13
UniRef50_Q4RIB1 Cluster: Chromosome 8 SCAF15044, whole genome sh... 41 0.13
UniRef50_Q7Q6Z7 Cluster: ENSANGP00000017664; n=1; Anopheles gamb... 41 0.13
UniRef50_Q8N5H7 Cluster: SH2 domain-containing protein 3C; n=33;... 41 0.13
UniRef50_UPI0000F2B3BE Cluster: PREDICTED: similar to Src-like-a... 41 0.18
UniRef50_UPI0000F1EB7D Cluster: PREDICTED: hypothetical protein;... 41 0.18
UniRef50_UPI0000E218D0 Cluster: PREDICTED: similar to SH2B adapt... 41 0.18
UniRef50_UPI0000D56E93 Cluster: PREDICTED: similar to SH2 domain... 41 0.18
UniRef50_UPI00006A1C31 Cluster: UPI00006A1C31 related cluster; n... 41 0.18
UniRef50_UPI00006A1C30 Cluster: UPI00006A1C30 related cluster; n... 41 0.18
UniRef50_Q8AVM4 Cluster: Sh2d3c-prov protein; n=5; Euteleostomi|... 41 0.18
UniRef50_Q9VHC3 Cluster: CG9379-PA; n=2; Drosophila melanogaster... 41 0.18
UniRef50_Q4JSB7 Cluster: Tensin; n=3; Culicidae|Rep: Tensin - An... 41 0.18
UniRef50_P18106 Cluster: Tyrosine-protein kinase Fps85D; n=12; E... 41 0.18
UniRef50_UPI0000D57904 Cluster: PREDICTED: similar to CG9098-PA,... 40 0.24
UniRef50_Q4RUJ4 Cluster: Chromosome 1 SCAF14995, whole genome sh... 40 0.24
UniRef50_Q4RFY9 Cluster: Chromosome undetermined SCAF15108, whol... 40 0.24
UniRef50_A7RK55 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.24
UniRef50_UPI000049A401 Cluster: hypothetical protein 90.t00015; ... 40 0.31
UniRef50_UPI00004D6B5A Cluster: SH2B adapter protein 3 (Lymphocy... 40 0.31
UniRef50_Q5RJ36 Cluster: Novel protein similar to vertebrate lym... 40 0.31
UniRef50_A4II17 Cluster: Putative uncharacterized protein; n=3; ... 40 0.31
UniRef50_A2RUZ0 Cluster: Zgc:158474 protein; n=4; Euteleostomi|R... 40 0.31
UniRef50_A7ASW0 Cluster: Asparagine rich protein, putative; n=1;... 40 0.31
UniRef50_Q9H6Q3 Cluster: Src-like-adapter 2; n=21; Euteleostomi|... 40 0.31
UniRef50_P08567 Cluster: Pleckstrin; n=32; Euteleostomi|Rep: Ple... 40 0.31
UniRef50_O00459 Cluster: Phosphatidylinositol 3-kinase regulator... 40 0.31
UniRef50_Q8I7C3 Cluster: LIM and SH3 domain protein Lasp; n=3; D... 40 0.31
UniRef50_UPI00015B56EF Cluster: PREDICTED: similar to GA18517-PA... 40 0.41
UniRef50_UPI0000F1F114 Cluster: PREDICTED: similar to pleckstrin... 40 0.41
UniRef50_UPI0000E48882 Cluster: PREDICTED: similar to tensin hom... 40 0.41
UniRef50_UPI0000E47C6E Cluster: PREDICTED: similar to Grb2 adapt... 40 0.41
UniRef50_UPI0000E1FA37 Cluster: PREDICTED: similar to signaling ... 40 0.41
UniRef50_UPI00003A9BD4 Cluster: PREDICTED: similar to SH2 domain... 40 0.41
UniRef50_UPI0000ECA6D9 Cluster: SH2B adapter protein 3 (Lymphocy... 40 0.41
UniRef50_Q08BD5 Cluster: Zgc:153920; n=3; Danio rerio|Rep: Zgc:1... 40 0.41
UniRef50_Q9NH62 Cluster: Tyrosine kinase 5; n=2; Schistosoma man... 40 0.41
UniRef50_Q54GT8 Cluster: Putative uncharacterized protein; n=1; ... 40 0.41
UniRef50_Q17BH3 Cluster: Putative uncharacterized protein; n=1; ... 40 0.41
UniRef50_O44235 Cluster: HrSH2 protein; n=1; Halocynthia roretzi... 40 0.41
UniRef50_A7T8K3 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.41
UniRef50_A7RU23 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.41
UniRef50_Q96JZ2 Cluster: Hematopoietic SH2 domain-containing pro... 40 0.41
UniRef50_Q8WV28 Cluster: B-cell linker protein; n=24; Eutheria|R... 40 0.41
UniRef50_UPI00015B58E2 Cluster: PREDICTED: similar to signal tra... 39 0.54
UniRef50_UPI0000E483A8 Cluster: PREDICTED: similar to plenty of ... 39 0.54
UniRef50_UPI0000D577C3 Cluster: PREDICTED: similar to CG8874-PB,... 39 0.54
UniRef50_UPI0000D56397 Cluster: PREDICTED: similar to Tensin-1; ... 39 0.54
UniRef50_Q6NRD3 Cluster: Posh protein; n=4; Tetrapoda|Rep: Posh ... 39 0.54
UniRef50_Q4SIP6 Cluster: Chromosome 21 SCAF14577, whole genome s... 39 0.54
UniRef50_Q29DT1 Cluster: GA17729-PA; n=1; Drosophila pseudoobscu... 39 0.54
UniRef50_A7T2F6 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 39 0.54
UniRef50_A0E6T7 Cluster: Chromosome undetermined scaffold_80, wh... 39 0.54
UniRef50_Q7Z6J0 Cluster: SH3 domain-containing RING finger prote... 39 0.54
UniRef50_Q9JID9 Cluster: SH2B adapter protein 2; n=16; Euteleost... 39 0.54
UniRef50_UPI0000D8A09F Cluster: myosin light chain kinase; n=1; ... 39 0.72
UniRef50_UPI000051AB4C Cluster: PREDICTED: similar to Plenty of ... 39 0.72
UniRef50_UPI00015A58A4 Cluster: UPI00015A58A4 related cluster; n... 39 0.72
UniRef50_O60880-5 Cluster: Isoform E of O60880 ; n=5; Eutheria|R... 39 0.72
UniRef50_Q9VRR9 Cluster: CG10479-PA; n=2; Sophophora|Rep: CG1047... 39 0.72
UniRef50_Q95ZL4 Cluster: Temporarily assigned gene name protein ... 39 0.72
UniRef50_Q86E31 Cluster: Clone ZZZ288 mRNA sequence; n=1; Schist... 39 0.72
UniRef50_Q5TT79 Cluster: ENSANGP00000027130; n=4; Endopterygota|... 39 0.72
UniRef50_Q5C0L2 Cluster: SJCHGC05893 protein; n=1; Schistosoma j... 39 0.72
UniRef50_Q18865 Cluster: Putative uncharacterized protein; n=5; ... 39 0.72
UniRef50_A7RRM1 Cluster: Predicted protein; n=1; Nematostella ve... 39 0.72
UniRef50_A4F2N7 Cluster: Mt-tensin-b; n=2; Molgula tectiformis|R... 39 0.72
UniRef50_O76041 Cluster: Nebulette; n=29; Tetrapoda|Rep: Nebulet... 39 0.72
UniRef50_UPI00015B5616 Cluster: PREDICTED: similar to suppressor... 38 0.95
UniRef50_UPI0000F1F44E Cluster: PREDICTED: similar to Src-like-a... 38 0.95
UniRef50_UPI00006A0FDA Cluster: Connector enhancer of kinase sup... 38 0.95
UniRef50_Q4SMI9 Cluster: Chromosome 18 SCAF14547, whole genome s... 38 0.95
UniRef50_Q17DJ2 Cluster: Signal transduction protein lnk-realted... 38 0.95
UniRef50_A7RI31 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.95
UniRef50_A5K4P1 Cluster: Asparagine-rich protein, putative; n=1;... 38 0.95
UniRef50_Q2U6I7 Cluster: Predicted protein; n=7; Trichocomaceae|... 38 0.95
UniRef50_Q08881 Cluster: Tyrosine-protein kinase ITK/TSK; n=18; ... 38 0.95
UniRef50_UPI0000F1E8AD Cluster: PREDICTED: hypothetical protein;... 38 1.3
UniRef50_UPI0000E492E7 Cluster: PREDICTED: hypothetical protein;... 38 1.3
UniRef50_UPI0000E45D4F Cluster: PREDICTED: similar to SH2 domain... 38 1.3
UniRef50_Q4SPM1 Cluster: Chromosome 16 SCAF14537, whole genome s... 38 1.3
UniRef50_Q4RKT7 Cluster: Chromosome 1 SCAF15025, whole genome sh... 38 1.3
UniRef50_A2BDR6 Cluster: SH2 domain containing 3C; n=5; Danio re... 38 1.3
UniRef50_Q9JL90 Cluster: Nebulin; n=23; Euteleostomi|Rep: Nebuli... 38 1.3
UniRef50_Q0TE22 Cluster: Putative uncharacterized protein; n=8; ... 38 1.3
UniRef50_Q9W4A9 Cluster: CG3208-PA, isoform A; n=5; Diptera|Rep:... 38 1.3
UniRef50_Q9VRS2 Cluster: CG32406-PA; n=3; Sophophora|Rep: CG3240... 38 1.3
UniRef50_Q380D8 Cluster: ENSANGP00000027059; n=2; Culicidae|Rep:... 38 1.3
UniRef50_Q17AB7 Cluster: Putative uncharacterized protein; n=1; ... 38 1.3
UniRef50_A7RI30 Cluster: Predicted protein; n=1; Nematostella ve... 38 1.3
UniRef50_A0NEZ5 Cluster: ENSANGP00000031260; n=4; Culicidae|Rep:... 38 1.3
UniRef50_Q9NRF3 Cluster: SH2B adaptor protein 1; n=33; Mammalia|... 38 1.3
UniRef50_Q59HB0 Cluster: SHC (Src homology 2 domain containing) ... 38 1.3
UniRef50_Q2MD52 Cluster: B-cell linker protein; n=7; Theria|Rep:... 38 1.3
UniRef50_P52735 Cluster: Protein vav-2; n=28; Euteleostomi|Rep: ... 38 1.3
UniRef50_P20929 Cluster: Nebulin; n=63; Euteleostomi|Rep: Nebuli... 38 1.3
UniRef50_Q6VYH9 Cluster: Hematopoietic SH2 domain-containing pro... 38 1.3
UniRef50_Q60I21 Cluster: TEC family protein tyrosine kinase; n=1... 38 1.7
UniRef50_Q5LQU2 Cluster: Carbon monoxide dehydrogenase F protein... 38 1.7
UniRef50_Q7Z4S9 Cluster: SH2 domain-containing protein 6; n=7; E... 38 1.7
UniRef50_Q5T4P1 Cluster: Phosphoinositide-3-kinase, regulatory s... 38 1.7
UniRef50_A6ND14 Cluster: Uncharacterized protein SH2D6; n=10; Eu... 38 1.7
UniRef50_Q6CQI3 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 38 1.7
UniRef50_Q1DYX0 Cluster: Putative uncharacterized protein; n=1; ... 38 1.7
UniRef50_A5DDC7 Cluster: Putative uncharacterized protein; n=1; ... 38 1.7
UniRef50_Q9NP31 Cluster: SH2 domain-containing protein 2A; n=23;... 38 1.7
UniRef50_UPI0000E479E4 Cluster: PREDICTED: similar to Sh2d3c-pro... 37 2.2
UniRef50_UPI0000499872 Cluster: hypothetical protein 17.t00066; ... 37 2.2
UniRef50_UPI000069FBD8 Cluster: tensin like C1 domain containing... 37 2.2
UniRef50_UPI000069FBD7 Cluster: tensin like C1 domain containing... 37 2.2
UniRef50_UPI000069FBD6 Cluster: tensin like C1 domain containing... 37 2.2
UniRef50_Q8A0S0 Cluster: Transcriptional regulator; n=3; Bactero... 37 2.2
UniRef50_Q55GV3 Cluster: P21-activated protein kinase; n=2; Dict... 37 2.2
UniRef50_Q6L0V3 Cluster: Tricorn protease; n=3; Thermoplasmatale... 37 2.2
UniRef50_P32790 Cluster: Cytoskeleton assembly control protein S... 37 2.2
UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX... 37 2.2
UniRef50_UPI000155BA92 Cluster: PREDICTED: similar to Fyn-relate... 37 2.9
UniRef50_UPI0000E4816C Cluster: PREDICTED: similar to phosphoino... 37 2.9
UniRef50_UPI0000D55E0B Cluster: PREDICTED: similar to CG4909-PA;... 37 2.9
UniRef50_UPI00005A0859 Cluster: PREDICTED: similar to SH2 domain... 37 2.9
UniRef50_UPI00015A734B Cluster: SH3 multiple domains 2 like; n=1... 37 2.9
UniRef50_Q6GP30 Cluster: MGC80721 protein; n=1; Xenopus laevis|R... 37 2.9
UniRef50_A5D8S5 Cluster: Si:dkey-15j16.4 protein; n=10; Euteleos... 37 2.9
UniRef50_Q6NR09 Cluster: RE08107p; n=6; Diptera|Rep: RE08107p - ... 37 2.9
UniRef50_Q9W420 Cluster: Transcription elongation factor SPT6; n... 37 2.9
UniRef50_P50745 Cluster: SH2B adapter protein 3; n=3; Rattus nor... 37 2.9
UniRef50_P34265 Cluster: Probable tyrosine-protein kinase kin-31... 37 2.9
UniRef50_UPI0000F1ED8A Cluster: PREDICTED: similar to TNS1 prote... 36 3.8
UniRef50_UPI00004990D7 Cluster: hypothetical protein 6.t00045; n... 36 3.8
UniRef50_P62993-2 Cluster: Isoform GRB3; n=9; Deuterostomia|Rep:... 36 3.8
UniRef50_Q13322-2 Cluster: Isoform 1 of Q13322 ; n=5; Homo/Pan/G... 36 3.8
UniRef50_Q5U4V8 Cluster: LOC398328 protein; n=5; Xenopus|Rep: LO... 36 3.8
UniRef50_Q4SBL7 Cluster: Chromosome 15 SCAF14667, whole genome s... 36 3.8
UniRef50_Q4S3B2 Cluster: Chromosome 4 SCAF14752, whole genome sh... 36 3.8
UniRef50_A5X5J0 Cluster: Rho guanine nucleotide exchange factor ... 36 3.8
UniRef50_A5C5Y3 Cluster: Putative uncharacterized protein; n=1; ... 36 3.8
UniRef50_Q54JS2 Cluster: Putative uncharacterized protein; n=1; ... 36 3.8
UniRef50_Q21055 Cluster: Protein tyrosine phosphatase protein 2;... 36 3.8
UniRef50_A7RZ47 Cluster: Predicted protein; n=1; Nematostella ve... 36 3.8
UniRef50_A7RXJ8 Cluster: Predicted protein; n=1; Nematostella ve... 36 3.8
UniRef50_A7RGQ1 Cluster: Predicted protein; n=1; Nematostella ve... 36 3.8
UniRef50_Q6CHN0 Cluster: Yarrowia lipolytica chromosome A of str... 36 3.8
UniRef50_Q5A898 Cluster: Putative uncharacterized protein BOI2; ... 36 3.8
UniRef50_Q2U6I5 Cluster: Ras GTPase-activating protein family - ... 36 3.8
UniRef50_Q6L260 Cluster: Putative uncharacterized protein; n=1; ... 36 3.8
UniRef50_Q45FX5 Cluster: Protein vav-1; n=4; Caenorhabditis|Rep:... 36 3.8
UniRef50_Q8TEJ3 Cluster: SH3 multiple domains protein 4 precurso... 36 3.8
UniRef50_Q13322 Cluster: Growth factor receptor-bound protein 10... 36 3.8
UniRef50_Q9NYB9 Cluster: Abl interactor 2; n=103; Euteleostomi|R... 36 3.8
UniRef50_Q8CBW3 Cluster: Abl interactor 1; n=74; Euteleostomi|Re... 36 3.8
UniRef50_UPI0000DB7594 Cluster: PREDICTED: similar to CG9098-PA,... 36 5.1
UniRef50_UPI0000D9C236 Cluster: PREDICTED: abl-interactor 1 isof... 36 5.1
UniRef50_UPI0000D556B9 Cluster: PREDICTED: similar to CG1657-PA;... 36 5.1
UniRef50_UPI000066052F Cluster: UPI000066052F related cluster; n... 36 5.1
UniRef50_Q4SR72 Cluster: Chromosome 11 SCAF14528, whole genome s... 36 5.1
UniRef50_Q4SC98 Cluster: Chromosome undetermined SCAF14659, whol... 36 5.1
UniRef50_A2AHL9 Cluster: Novel protein containing SH3 domains; n... 36 5.1
UniRef50_A6CFF1 Cluster: Polyhydroxyalkanoate synthesis represso... 36 5.1
UniRef50_Q9VX18 Cluster: CG8146-PA; n=1; Drosophila melanogaster... 36 5.1
UniRef50_Q54U31 Cluster: SH2 domain-containing protein; n=1; Dic... 36 5.1
UniRef50_A2FFI6 Cluster: GTPase-activator protein, putative; n=1... 36 5.1
UniRef50_A2E9Q3 Cluster: GTPase-activator protein, putative; n=1... 36 5.1
UniRef50_Q59G41 Cluster: Abl-interactor 1 variant; n=46; Eumetaz... 36 5.1
UniRef50_A6R4G3 Cluster: Predicted protein; n=1; Ajellomyces cap... 36 5.1
UniRef50_UPI0000D9D5A4 Cluster: PREDICTED: similar to putative s... 36 6.7
UniRef50_UPI0000D5645D Cluster: PREDICTED: similar to CG17367-PB... 36 6.7
UniRef50_Q85476 Cluster: (recovered insertion mutant of B77) src... 36 6.7
UniRef50_Q6NV36 Cluster: Baiap2l1a protein; n=7; Danio rerio|Rep... 36 6.7
UniRef50_Q4T639 Cluster: Chromosome undetermined SCAF8942, whole... 36 6.7
UniRef50_Q4SYA1 Cluster: Chromosome undetermined SCAF12132, whol... 36 6.7
UniRef50_Q1LWW1 Cluster: Novel protein similar to vertebrate pho... 36 6.7
UniRef50_Q1L954 Cluster: Novel protein similar to vertebrate G p... 36 6.7
UniRef50_Q968Z2 Cluster: Putative uncharacterized protein; n=2; ... 36 6.7
UniRef50_Q7RTG4 Cluster: Myosin light chain kinase; n=5; Plasmod... 36 6.7
UniRef50_Q7JVF1 Cluster: LP02169p; n=2; Sophophora|Rep: LP02169p... 36 6.7
UniRef50_Q4N248 Cluster: Protein kinase, putative; n=2; Theileri... 36 6.7
UniRef50_Q1DYT2 Cluster: Putative uncharacterized protein; n=1; ... 36 6.7
UniRef50_O60504 Cluster: Vinexin; n=20; Eutheria|Rep: Vinexin - ... 36 6.7
UniRef50_Q63HR2 Cluster: Tensin-like C1 domain-containing phosph... 36 6.7
UniRef50_Q9BRG2 Cluster: SH2 domain-containing protein 3A; n=11;... 36 6.7
UniRef50_O15259 Cluster: Nephrocystin-1; n=23; Euteleostomi|Rep:... 36 6.7
UniRef50_Q12163 Cluster: NAP1-binding protein 2; n=4; Saccharomy... 36 6.7
UniRef50_P34416 Cluster: LIM and SH3 domain protein F42H10.3; n=... 36 6.7
UniRef50_UPI000155CF29 Cluster: PREDICTED: similar to chromosome... 35 8.9
UniRef50_UPI0000F2BE38 Cluster: PREDICTED: similar to IQ motif c... 35 8.9
UniRef50_UPI0000F2115F Cluster: PREDICTED: similar to tensin lik... 35 8.9
UniRef50_UPI0000F2002E Cluster: PREDICTED: hypothetical protein;... 35 8.9
UniRef50_UPI0000DB6CD0 Cluster: PREDICTED: similar to LIM and SH... 35 8.9
UniRef50_UPI00006A0ADF Cluster: Tensin-1.; n=5; Xenopus tropical... 35 8.9
UniRef50_UPI0000F318C3 Cluster: SH2B adapter protein 3 (Lymphocy... 35 8.9
UniRef50_Q4SRP3 Cluster: Chromosome undetermined SCAF14505, whol... 35 8.9
UniRef50_Q4SM94 Cluster: Chromosome 3 SCAF14553, whole genome sh... 35 8.9
UniRef50_Q86SD5 Cluster: Tensin homologue; n=1; Ciona intestinal... 35 8.9
UniRef50_Q7Q350 Cluster: ENSANGP00000004820; n=2; Culicidae|Rep:... 35 8.9
UniRef50_Q54FG5 Cluster: Putative uncharacterized protein; n=1; ... 35 8.9
UniRef50_A2G2R5 Cluster: GTPase-activator protein, putative; n=1... 35 8.9
UniRef50_Q7Z7G1 Cluster: MIST; n=18; Eutheria|Rep: MIST - Homo s... 35 8.9
UniRef50_O15524 Cluster: Suppressor of cytokine signaling 1; n=1... 35 8.9
UniRef50_Q9UQQ2 Cluster: SH2B adapter protein 3; n=15; Tetrapoda... 35 8.9
>UniRef50_Q8IR23 Cluster: CG9209-PA, isoform A; n=6;
Endopterygota|Rep: CG9209-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 954
Score = 1271 bits (3148), Expect = 0.0
Identities = 608/887 (68%), Positives = 710/887 (80%), Gaps = 10/887 (1%)
Query: 52 NGERQAVLAPPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGI 111
NGER A++APPE+EWYHGRLDRY++E RL +SK GSYLVRESDRKPGSYVLSY GRTGI
Sbjct: 70 NGERPAIIAPPESEWYHGRLDRYSAESRLRGSSKLGSYLVRESDRKPGSYVLSYYGRTGI 129
Query: 112 NHFRITAVCGDYYIGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAI 171
NHFRITAVCGD+YIGGRQF SL++LVG+Y+ CSDLLKRERL NDKKRVVAI
Sbjct: 130 NHFRITAVCGDFYIGGRQFISLSDLVGYYTSCSDLLKRERLAIPVAPPEPVNDKKRVVAI 189
Query: 172 LPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNT 231
LPYTKMP+TDEL+FQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELV+DLD SIDPNT
Sbjct: 190 LPYTKMPETDELSFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVDDLDVSIDPNT 249
Query: 232 VFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY 291
VF WFHPNCTK+EAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY
Sbjct: 250 VFPWFHPNCTKNEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY 309
Query: 292 LMGGRTFECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQSTTGAAAEKIYATLREC 351
LMGGRTFECLDAVINRYRKEQIVEGH+L P++ QQ AAEKIYATLREC
Sbjct: 310 LMGGRTFECLDAVINRYRKEQIVEGHSLNHPVVNGIQPEFNQQYVVEKAAEKIYATLREC 369
Query: 352 RDQIGLKKTKGIKHYGYLNKKSDKGAKKWKPLYCVLLQEGTDTHLYFYDSPKRTKPKGLI 411
RDQIGLKK KGIKH+G+LNKKSDK KWK LY L+ +G++T L FYD+PK+TKPKGLI
Sbjct: 370 RDQIGLKKIKGIKHHGHLNKKSDK-TTKWKQLYFALINDGSETQLCFYDNPKKTKPKGLI 428
Query: 412 DLSCAYLYQVHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQ 471
DLSCAYLYQ H+SLWE+ +CFQ+VERALPCL+T T+L A + WI +L+ C Q
Sbjct: 429 DLSCAYLYQCHDSLWERPYCFQIVERALPCLATVTYLCAPSQESYVEWINSLKAQCDSQL 488
Query: 472 ARHQCKVGRVSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDPHWXX 531
+R Q KV R+ + L + L AHRLP +L P P+ + L V +TR + +P+P W
Sbjct: 489 SRAQKKVSRLRELRCLNLHVLEAHRLPFKLVPHPYCSISLNQVKVGKTRVKIAPEPVWEE 548
Query: 532 XXXXXXMPPDVTSLTITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPIGE 591
+PPDV SLTIT+ + GKRGK+SEVAELTI+L++L NG+E E WY L GMTP+GE
Sbjct: 549 EFVLDDVPPDVVSLTITLISRGKRGKDSEVAELTIDLSSLKNGQETEGWYQLTGMTPMGE 608
Query: 592 WGSLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRTDRQPLATSVLNTFAE 651
WGSLRLR+RY+ +L+MP EEY+PL+QLLLE + AVKALA+LC DR PLAT++L F +
Sbjct: 609 WGSLRLRMRYLDDLIMPCEEYSPLQQLLLESELYAVKALAELCHNDRVPLATALLRVFRQ 668
Query: 652 CGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLI 711
R EL R L AEV RE + TLFRGASLAT ++D +MR C FLQ+A+SET+Q+++
Sbjct: 669 EKRETELIRMLCQAEVTRENETTTLFRGASLATTLMDLYMRTECSGFLQSAVSETVQRIL 728
Query: 712 DSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAV 771
+SKQ+AELNPTKMD DDAC NAEFLL ILD +T SIFTSP+ACP+ VR++C CLQ+A +
Sbjct: 729 ESKQSAELNPTKMDVNDDACTNAEFLLQILDLVTQSIFTSPDACPRNVRFICSCLQKAVM 788
Query: 772 AKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLAN 831
AKWP ER VRTRVVSGFIFLRL+CPAL+ PR + LV PP A RSL+MVAKCLQNLAN
Sbjct: 789 AKWPTERLVRTRVVSGFIFLRLLCPALLNPRQFGLVSETPPMAATRSLVMVAKCLQNLAN 848
Query: 832 LVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSP------PNSNVNF-EIAK 884
L+EFG KE YMEVVNPFILKNKERM+VFLDQLS+V DP N P ++N+N + +
Sbjct: 849 LIEFGGKEQYMEVVNPFILKNKERMIVFLDQLSSVNDP-NQPLGMFVEQSTNLNSQDTGR 907
Query: 885 ELATLHHICVAHLTELQGLAKNQPAIRKLVTVTEMLTKHKQKYLEMI 931
ELATLHHICV+H EL L+ N +I+KLVTVT+MLTKHK KY EMI
Sbjct: 908 ELATLHHICVSHSQELHELS-NILSIKKLVTVTDMLTKHKLKYREMI 953
>UniRef50_P20936 Cluster: Ras GTPase-activating protein 1; n=50;
Euteleostomi|Rep: Ras GTPase-activating protein 1 - Homo
sapiens (Human)
Length = 1047
Score = 725 bits (1793), Expect = 0.0
Identities = 376/879 (42%), Positives = 550/879 (62%), Gaps = 24/879 (2%)
Query: 60 APPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGI-NHFRITA 118
APP +WYHG+LDR +EERL A K GSYL+RESDR+PGS+VLS+L + + NHFRI A
Sbjct: 175 APPTNQWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIA 234
Query: 119 VCGDYYIGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMP 178
+CGDYYIGGR+F SL++L+G+YSH S LLK E+L D++RV AILPYTK+P
Sbjct: 235 MCGDYYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEPVEDRRRVRAILPYTKVP 294
Query: 179 DTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHP 238
DTDE++F KGD+F VHN++ DGW+WVT RT EQG+I +LVE++ DP+ WFH
Sbjct: 295 DTDEISFLKGDMFIVHNELEDGWMWVTNLRTDEQGLIVEDLVEEVGREEDPHEGKIWFHG 354
Query: 239 NCTKSEAVDMLVKAGPG-SFLVRPSDNSPGDYSLFFHINNQIQRFRI-EKKGVRYLMGGR 296
+K EA ++L+ G SFLVRPSDN+PGDYSL+F N IQRF+I +++MGGR
Sbjct: 355 KISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKICPTPNNQFMMGGR 414
Query: 297 TFECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQSTTGAAAEKIYATLR-ECRDQI 355
+ + +I+ YRKEQIVEG+ L +P+ + + G ++IY T+R + +D
Sbjct: 415 YYNSIGDIIDHYRKEQIVEGYYLKEPVPMQDQEQVLNDTVDG---KEIYNTIRRKTKDAF 471
Query: 356 GLKKTKGIKHYGYLNKKSDKGAKKWKPLYCVLLQEGTDTHLYFYDSPKR-TKPKGLIDLS 414
K I GYL KK KG K+WK LY +L EG+D L +++S KR TKPKGLIDLS
Sbjct: 472 ----YKNIVKKGYLLKKG-KG-KRWKNLYFIL--EGSDAQLIYFESEKRATKPKGLIDLS 523
Query: 415 CAYLYQVHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARH 474
+Y VH+SL+ + CFQ+V + + A T + W++ L+ C +++
Sbjct: 524 VCSVYVVHDSLFGRPNCFQIVVQHFSEEHYIFYFAGETPEQAEDWMKGLQAFCNLRKSSP 583
Query: 475 QCKVGRVSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDPHWXXXXX 534
R+ V L + AH+LP + P+ + L + VA+T R +P W
Sbjct: 584 GTSNKRLRQVSSLVLHIEEAHKLPVKHFTNPYCNIYLNSVQVAKTHAREGQNPVWSEEFV 643
Query: 535 XXXMPPDVTSLTITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPIG--EW 592
+PPD+ IT+ N K+ K+ ++ + +L+ L G +EW+ L P+ E
Sbjct: 644 FDDLPPDINRFEITLSNKTKKSKDPDILFMRCQLSRLQKGHATDEWFLLSSHIPLKGIEP 703
Query: 593 GSLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRTDRQPLATSVLNTFAEC 652
GSLR+R RY E +MP EEY+ ++L+L+ + V AL+ +C DR LA+ +L F
Sbjct: 704 GSLRVRARYSMEKIMPEEEYSEFKELILQKELHVVYALSHVCGQDRTLLASILLRIFLHE 763
Query: 653 GRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLID 712
+ L L E++ E + TLFR +LA+ +++++M+A F+ A+ ++I K+++
Sbjct: 764 KLESLLLCTLNDREISMEDEATTLFRATTLASTLMEQYMKATATQFVHHALKDSILKIME 823
Query: 713 SKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVA 772
SKQ+ EL+P+K++ +D N LL IL ++ IF + E P +RY+ GCLQ++
Sbjct: 824 SKQSCELSPSKLEKNEDVNTNLTHLLNILSELVEKIFMASEILPPTLRYIYGCLQKSVQH 883
Query: 773 KWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANL 832
KWP +RTRVVSGF+FLRLICPA++ PR + ++ +P P A R+L++VAK +QNLANL
Sbjct: 884 KWPTNTTMRTRVVSGFVFLRLICPAILNPRMFNIISDSPSPIAARTLILVAKSVQNLANL 943
Query: 833 VEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHI 892
VEFGAKEPYME VNPFI NK RM++FLD+L NVP+ ++ +S +++++LA LH I
Sbjct: 944 VEFGAKEPYMEGVNPFIKSNKHRMIMFLDELGNVPELPDTTEHSRT--DLSRDLAALHEI 1001
Query: 893 CVAHLTELQGLAK----NQPAIRKLVTVTEMLTKHKQKY 927
CVAH EL+ L+ Q ++KL+ +TE+L + + +Y
Sbjct: 1002 CVAHSDELRTLSNERGAQQHVLKKLLAITELLQQKQNQY 1040
>UniRef50_UPI00015B62FA Cluster: PREDICTED: similar to ras gtpase
activating protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ras gtpase activating protein -
Nasonia vitripennis
Length = 879
Score = 665 bits (1642), Expect = 0.0
Identities = 311/386 (80%), Positives = 338/386 (87%), Gaps = 4/386 (1%)
Query: 60 APPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAV 119
APPE +WYHGRLDR+T+EERL AS+ GSYLVRESDRKPGSYVLSYLGRTGINHFRITAV
Sbjct: 71 APPENQWYHGRLDRFTAEERLRDASRLGSYLVRESDRKPGSYVLSYLGRTGINHFRITAV 130
Query: 120 CGDYYIGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPD 179
CGDYYIGGRQF+SL +LV +Y+HCSDLLK+ERL NDKKR+VAILPYTKMPD
Sbjct: 131 CGDYYIGGRQFNSLMDLVAYYTHCSDLLKKERLIHPTPPPEPVNDKKRIVAILPYTKMPD 190
Query: 180 TDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPN 239
TDEL+FQKGDIFFVHNDMGDGWLWVTAHRTGEQG+IFRELV+DLD SIDPNTVFSWFHPN
Sbjct: 191 TDELSFQKGDIFFVHNDMGDGWLWVTAHRTGEQGLIFRELVDDLDDSIDPNTVFSWFHPN 250
Query: 240 CTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGGRTFE 299
TKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGGRTFE
Sbjct: 251 VTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGGRTFE 310
Query: 300 CLDAVINRYRKEQIVEGHTLGQPLIAE-GHTIEPQQSTTGAAAEKIYATLRECRDQIGLK 358
CLDAVINRYRKEQIVEGHTL Q ++ E T+ + AEKIYATLRECR+Q G K
Sbjct: 311 CLDAVINRYRKEQIVEGHTLVQAMVTEPDGTVRVNKEV--QHAEKIYATLRECREQSGAK 368
Query: 359 KTKGIKHYGYLNKKSDKGAKKWKPLYCVLLQEGTDTHLYFYDSPKRTKPKGLIDLSCAYL 418
K KGIK GYL KKS+K KKWK LY VL+ + +DTHLY YD+PKRTKPKGLIDLSCAYL
Sbjct: 369 KNKGIKMQGYLEKKSEKN-KKWKALYFVLVVDASDTHLYLYDNPKRTKPKGLIDLSCAYL 427
Query: 419 YQVHESLWEKEFCFQLVERALPCLST 444
YQVHES++++ CFQLVERALPCLST
Sbjct: 428 YQVHESVFDRPHCFQLVERALPCLST 453
Score = 548 bits (1353), Expect = e-154
Identities = 255/398 (64%), Positives = 321/398 (80%), Gaps = 3/398 (0%)
Query: 538 MPPDVTSLTITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPIGEWGSLRL 597
+PPDV S ++T++N GKR K++EVAEL +EL++LANGEE++EWYP G+TPIG+WG+LRL
Sbjct: 482 VPPDVMSFSLTLYNKGKRSKDTEVAELIVELSSLANGEEMDEWYPFAGVTPIGDWGALRL 541
Query: 598 RIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRTDRQPLATSVLNTFAECGRGAE 657
R+RY +L MP EEY+PL+QLLL+P + VKALAD+C DR PLA S+L F R A+
Sbjct: 542 RLRYRHDLAMPPEEYSPLQQLLLDPELHVVKALADVCHLDRIPLANSLLRIFRHEKREAD 601
Query: 658 LARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTA 717
L + L AEV +E + TLFR ASL T ++D +M++ C FL++A+ +TI KLIDSKQ+
Sbjct: 602 LLKSLNQAEVDKEDETPTLFRAASLTTTLMDLYMKSVCTSFLKSALQDTIIKLIDSKQSC 661
Query: 718 ELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNE 777
ELNP+KMDSP+DAC+NAEFLL +LD++TLSIFTSP+ CPK +RY+C CLQRA VAKWP+E
Sbjct: 662 ELNPSKMDSPEDACSNAEFLLQVLDEVTLSIFTSPDMCPKSLRYICCCLQRAVVAKWPHE 721
Query: 778 RFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGA 837
R VRTRVVSGFIFLRL+CPA++ P+++ L+ +P P A RSL+MVAKCLQNLANLVEFG
Sbjct: 722 RLVRTRVVSGFIFLRLLCPAILNPKSFNLIAESPSPAATRSLVMVAKCLQNLANLVEFGG 781
Query: 838 KEPYMEVVNPFILKNKERMVVFLDQLSNV---PDPGNSPPNSNVNFEIAKELATLHHICV 894
KEPYMEVVNPFILKNKERMVVFLDQLSNV P+P P +IAK+LATLHHICV
Sbjct: 782 KEPYMEVVNPFILKNKERMVVFLDQLSNVSDKPEPECISPRGKCILDIAKDLATLHHICV 841
Query: 895 AHLTELQGLAKNQPAIRKLVTVTEMLTKHKQKYLEMIR 932
+HL ELQ L+K QP I++LVTVTEML+ HKQ+Y E +R
Sbjct: 842 SHLKELQILSKQQPTIKRLVTVTEMLSNHKQRYKEKLR 879
>UniRef50_UPI0000E49CFC Cluster: PREDICTED: similar to Ras
GTPase-activating protein 1 (GTPase-activating protein)
(GAP) (Ras p21 protein activator) (p120GAP) (RasGAP);
n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to Ras GTPase-activating protein 1
(GTPase-activating protein) (GAP) (Ras p21 protein
activator) (p120GAP) (RasGAP) - Strongylocentrotus
purpuratus
Length = 628
Score = 495 bits (1222), Expect = e-138
Identities = 259/571 (45%), Positives = 356/571 (62%), Gaps = 19/571 (3%)
Query: 60 APPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAV 119
APPE EWYHG LDR ++E RL AA K GSYLVRES+RKPGSYVLSYLG+ GINHFR+TAV
Sbjct: 62 APPENEWYHGCLDRQSAELRLNAADKPGSYLVRESERKPGSYVLSYLGQRGINHFRVTAV 121
Query: 120 CGDYYIGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPD 179
CGD+Y+GGRQF +L EL+G+Y+H S++LK ERL +DKK+VVA LPY K+PD
Sbjct: 122 CGDFYVGGRQFQTLPELIGYYTHISNILKNERLQYPAPPPEPVDDKKKVVATLPYNKVPD 181
Query: 180 TDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPN 239
TDEL+F G++F VHN++G GWLWVT+ R+GE G+I ++LV+ ++ IDPN WFH N
Sbjct: 182 TDELSFSAGEVFVVHNELGGGWLWVTSQRSGESGIIVQDLVKPVEGEIDPNEGKVWFHGN 241
Query: 240 CTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGGRTF 298
+K EA + L K G G FL+R SD +PGDYSL F N IQRFRI+K+ +Y+MGGR +
Sbjct: 242 VSKEEAAETLWKDGDIGGFLIRNSDKNPGDYSLSFRGPNTIQRFRIQKQQRQYVMGGRYY 301
Query: 299 ECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQSTTGAAAEKIYATLRECRDQ-IGL 357
LDA+++ Y+KE+I++G L P + + Q ++T ++ Y LR R GL
Sbjct: 302 NSLDAIVDHYKKEEIIDGFKLRDPTAPK--KFKNQTTSTEDSSPMNYEELRRRRSSGFGL 359
Query: 358 KKTKG----IKHYGYLNKKSDKGAKKWKPLYCVLLQEGTDTHLYFYDSPKRTKPKGLIDL 413
G I G+L+KKS K KKWK + +L T+ HLY++D+ RTKP+GLIDL
Sbjct: 360 HIMTGMADSIIKQGHLSKKSQK-HKKWKTYFFLL--NATEQHLYYFDNDARTKPRGLIDL 416
Query: 414 SCAYLYQVHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCV----P 469
A +Y VHESL+ + CFQ+V RAL L +L A + E+ W++ LR C
Sbjct: 417 GYASVYAVHESLFARPNCFQIVVRALNDLQVF-YLNAESQELEKEWVQVLRSCCSKAGWT 475
Query: 470 QQARHQCKVGRVSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDPHW 529
Q++ + RV + LR+R L AH + ++ P + V L V RT + +P+P W
Sbjct: 476 TQSQRGSRKRRVKQLKSLRLRILEAHNISSKQIPHAYCVVSLNEVKVGRTPVQQAPNPVW 535
Query: 530 XXXXXXXXMPPDVTSLTITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLV---GM 586
+ S TI + N KR K + V ++ L L NG +EWYPL+
Sbjct: 536 DEEFMFDDFRDESDSFTIEICNGAKRAKPTPVCRTSVLLDRLTNGSVSDEWYPLISAANQ 595
Query: 587 TPIGEWGSLRLRIRYMQELVMPREEYNPLRQ 617
+ E GS+R R +++ E +MP EEY+PL++
Sbjct: 596 SKSVEMGSVRARAQFISETLMPIEEYSPLKE 626
>UniRef50_A7SJB4 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 681
Score = 482 bits (1188), Expect = e-134
Identities = 259/684 (37%), Positives = 407/684 (59%), Gaps = 15/684 (2%)
Query: 255 GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGGRTFECLDAVINRYRKEQIV 314
GSF++RPSD SPGDYSL + + RF I ++G +Y MGGR F +D V+ RY+ E IV
Sbjct: 7 GSFMIRPSDKSPGDYSLSLRYQDGVTRFLIRRQGQQYTMGGRVFCSIDDVVKRYKHEHIV 66
Query: 315 EGHTLGQPLIAEGHTIEPQQSTTGA--AAEKI--YATLRECRDQIGLKKT-KGIKHYGYL 369
EG +L +P++ P + TT + ++++ + + Q+ + T + GYL
Sbjct: 67 EGLSLNEPVLRPSVLEIPNRPTTPSNRCSDQMDGFTFPPQTSGQVSIINTSQQASKRGYL 126
Query: 370 NKKSDKGAKKWKPLYCVLLQEGTDTHLYFYDSPKRTKPKGLIDLSCAYLYQVHESLWEKE 429
KK + KWK ++CVL + + L F+++ KRTKPK L+DL+ + +Y V ES + +
Sbjct: 127 VKKGHRN--KWKRMFCVL--DADEQRLSFFENEKRTKPKMLLDLTFSTVYAVLESFFGRP 182
Query: 430 FCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGRVSWVLWLRV 489
CFQ+V RAL S T+L A+T W++A++ +C ++ V V + L +
Sbjct: 183 NCFQVVVRALG-ESRMTYLCADTPDLANEWMDAVQKICGKSKSLDVIDVD-VKQLRSLEL 240
Query: 490 RCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDPHWXXXXXXXXMPPDVTSLTITV 549
+ AH+LP P+ V L RT+ P W +P DV+S T+++
Sbjct: 241 NVIEAHKLPLNKVSHPYCMVSLNEVKTCRTKTFEGQTPLWNEEFKFNDLPSDVSSFTLSL 300
Query: 550 HNTGKRGKESEVAELTIELANLANGEEIEEWYPLVGMTP-IGEWGSLRLRIRYMQELVMP 608
+N R K+ + + + L L G+ +++WYPL + E G++R+R+++ E++MP
Sbjct: 301 YNKSWRTKDVLIGHVLVPLNKLPKGQTVDDWYPLAAASHGKAEVGNVRIRVKFTHEIIMP 360
Query: 609 REEYNPLRQLLLEPGIPAVKALADLCRTDRQPLATSVLNTFAECGRGAELARELTCAEVA 668
EEY L+++LL+ + AV AL +C+ DR LA+++L F + L + + E+
Sbjct: 361 VEEYEALKEILLDEDLVAVTALGQVCK-DRVVLASTLLKIFRHEKQEIFLLKTMNAREIE 419
Query: 669 REGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPD 728
++ + TLFRGASLAT+++D++M+ P+LQ I + I K+++ KQ+ ELNP KM+
Sbjct: 420 KQDEQATLFRGASLATSLMDQYMKMVAIPYLQHTIKDVILKILECKQSCELNPAKMEKGA 479
Query: 729 DACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGF 788
D N + LL L + +IFTS E CPK +RYL GCLQ+ KW + + VRTRVVSGF
Sbjct: 480 DTVVNLKQLLEFLFEAIDAIFTSAEECPKTLRYLFGCLQQNVKDKWADNQTVRTRVVSGF 539
Query: 789 IFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPF 848
+FLRL CPA++ P+ L+ P A R+L +VAKCLQ LANLVEFGAKE M VNPF
Sbjct: 540 LFLRLFCPAIMNPKTCNLMSELPSATAARTLTLVAKCLQKLANLVEFGAKESCMTPVNPF 599
Query: 849 ILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHICVAHLTELQGLAKNQP 908
+ KN+ERMV F+D+LS+V + + + V+ + A++LA+LH +C+ + EL+ L+ Q
Sbjct: 600 MQKNRERMVSFMDELSDVRECPKT--HEQVSSDPARDLASLHDLCIVYENELKQLSTTQT 657
Query: 909 AIRKLVTVTEMLTKHKQKYLEMIR 932
++KLV+V E L + +Q+Y++ R
Sbjct: 658 DLKKLVSVIEALRRREQQYVQESR 681
Score = 47.6 bits (108), Expect = 0.002
Identities = 22/56 (39%), Positives = 32/56 (57%)
Query: 87 GSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYIGGRQFDSLTELVGFYSH 142
GS+++R SD+ PG Y LS + G+ F I Y +GGR F S+ ++V Y H
Sbjct: 7 GSFMIRPSDKSPGDYSLSLRYQDGVTRFLIRRQGQQYTMGGRVFCSIDDVVKRYKH 62
>UniRef50_Q4RUN4 Cluster: Chromosome 12 SCAF14993, whole genome
shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
Chromosome 12 SCAF14993, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1136
Score = 412 bits (1015), Expect = e-113
Identities = 238/638 (37%), Positives = 359/638 (56%), Gaps = 37/638 (5%)
Query: 299 ECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQSTTGAAAEKIYATL-RECRDQIGL 357
+ +D +I+ Y+KEQIVEG+ L +P+ + + Q +IY T+ R+ +D
Sbjct: 458 DSVDDIIDHYKKEQIVEGYNLKEPVSVQQ---QEQVFADTVDGREIYNTIKRKTKDAF-- 512
Query: 358 KKTKGIKHYGYLNKKSDKGAKKWKPLYCVLLQEGTDTHLYFYDSPKR-TKPKGLIDLSCA 416
K I GYL KG K+WK LY +L EG D L +++S KR TKPKGLIDLS
Sbjct: 513 --YKNIVKKGYLLFNKGKG-KRWKNLYFIL--EGNDAQLIYFESEKRATKPKGLIDLSVC 567
Query: 417 YLYQVHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVP-QQARHQ 475
+Y VH+SL+ + CFQ+V + + A + + W++ L+ LC ++ Q
Sbjct: 568 SVYGVHDSLFGRPNCFQIVVQHFSEEQYIFYFAGEAPEQAQDWMKCLQTLCSNLRKTTQQ 627
Query: 476 CKVGRVSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDPHWXXXXXX 535
R+ V L + AH+LP + P+ + L + VA+T PR +P +
Sbjct: 628 PSNKRLRQVSSLMLYVEEAHKLPVKYFTNPYCNIYLNSVQVAKTHPREGQNPVFTEEFIF 687
Query: 536 XXMPPDVTSLTITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPIG--EWG 593
+ ++ I++ N K+ KES++ + +L L G+ I+EW+PL P+ E G
Sbjct: 688 DDLSSEINRFEISLSNKTKKSKESDILFMRCQLNRLQKGQMIDEWFPLSSHVPLKGIEPG 747
Query: 594 SLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRTDRQPLATSVLNTFAECG 653
SLR+R RY E +MP EEY+ ++++L+ + ALA +C DR LA+ +L F
Sbjct: 748 SLRVRARYSVEKIMPEEEYSEFKEMILQKEFHVIYALAHVCGQDRTLLASLLLKIFRHEK 807
Query: 654 RGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDS 713
A L R L E+ E + TLFR +LA+ +++++M+A PF+ A+ +TI K+++S
Sbjct: 808 AEAPLLRTLNDREINMEDEATTLFRATTLASTLMEQYMKATATPFVHHALKDTILKIMES 867
Query: 714 KQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAK 773
KQ+ ELNP+K++ +D N LL IL ++ IF + E P +R++ GCLQ++ K
Sbjct: 868 KQSCELNPSKLEKNEDVNLNLSHLLNILSELVEKIFMAAEILPPTLRFIYGCLQKSVQQK 927
Query: 774 WPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLV 833
WPN +RTRVVSGF+FLRLICPA++ PR + ++ P A R+L +VAK +QNLANLV
Sbjct: 928 WPNNTTMRTRVVSGFVFLRLICPAILNPRMFNIITDPPSSAAGRTLTLVAKSVQNLANLV 987
Query: 834 EFGAKEPYMEVVNPFILKNKERMVVFLDQLS------------------NVPDPGNSP-- 873
EFGAKEPYME VNPFI NK RM++FLD+L VP N P
Sbjct: 988 EFGAKEPYMEGVNPFIKNNKHRMIMFLDELGVSFAGQTPVMLECFGASVYVPCSQNVPDL 1047
Query: 874 PNSNVNF--EIAKELATLHHICVAHLTELQGLAKNQPA 909
P +F +++++LA LH +CVAH EL+ L+ + A
Sbjct: 1048 PEVTEHFRTDLSRDLAALHEVCVAHSDELRTLSNGRGA 1085
Score = 276 bits (676), Expect = 2e-72
Identities = 134/247 (54%), Positives = 177/247 (71%), Gaps = 8/247 (3%)
Query: 60 APPET-EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGI-NHFRIT 117
+PP WYHG+LDR +EERL A GSYL+RESDR+PGS+VLS+L T + NHFRI
Sbjct: 178 SPPRMPRWYHGKLDRTIAEERLRQARNPGSYLIRESDRRPGSFVLSFLSMTNVVNHFRII 237
Query: 118 AVCGDYYIGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKM 177
A+CGDYYIGGR+F SL++L+G+YS+ S LLK E+L D++RV AILPYTK+
Sbjct: 238 AMCGDYYIGGRRFSSLSDLIGYYSYVSCLLKGEKLLSPVAPPEPVEDRRRVRAILPYTKV 297
Query: 178 PDTDEL----TFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVF 233
PDTDE+ TF +GD+F VHN++ DGW+WV+ RT EQG+I ++LVE++ DP+
Sbjct: 298 PDTDEIRQVSTFLQGDMFIVHNELDDGWMWVSNVRTEEQGLIVKDLVEEVGREEDPHEGK 357
Query: 234 SWFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIE-KKGVRY 291
W+H + TK EA ++L+ G SFLVRPSDN+PGDYSLFF N+ IQRF+I +Y
Sbjct: 358 VWYHGHITKKEAYNLLMTVGQVCSFLVRPSDNTPGDYSLFFRTNDIIQRFKISPTSNNQY 417
Query: 292 LMGGRTF 298
+MGGR +
Sbjct: 418 MMGGRYY 424
Score = 52.0 bits (119), Expect = 7e-05
Identities = 31/92 (33%), Positives = 47/92 (51%), Gaps = 3/92 (3%)
Query: 235 WFHPNCTKSEAVDMLVKA-GPGSFLVRPSDNSPGDYSL-FFHINNQIQRFRIEKKGVRYL 292
W+H ++ A + L +A PGS+L+R SD PG + L F + N + FRI Y
Sbjct: 185 WYHGKLDRTIAEERLRQARNPGSYLIRESDRRPGSFVLSFLSMTNVVNHFRIIAMCGDYY 244
Query: 293 MGGRTFECLDAVINRYRKEQ-IVEGHTLGQPL 323
+GGR F L +I Y +++G L P+
Sbjct: 245 IGGRRFSSLSDLIGYYSYVSCLLKGEKLLSPV 276
Score = 45.2 bits (102), Expect = 0.008
Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGD-YY 124
WYHG + + + L + S+LVR SD PG Y L + I F+I+ + Y
Sbjct: 359 WYHGHITKKEAYNLLMTVGQVCSFLVRPSDNTPGDYSLFFRTNDIIQRFKISPTSNNQYM 418
Query: 125 IGGRQFD 131
+GGR ++
Sbjct: 419 MGGRYYN 425
>UniRef50_UPI0000E4852D Cluster: PREDICTED: similar to Ras
GTPase-activating protein 1 (GTPase-activating protein)
(GAP) (Ras p21 protein activator) (p120GAP) (RasGAP),
partial; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Ras GTPase-activating protein 1
(GTPase-activating protein) (GAP) (Ras p21 protein
activator) (p120GAP) (RasGAP), partial -
Strongylocentrotus purpuratus
Length = 353
Score = 252 bits (617), Expect = 3e-65
Identities = 128/265 (48%), Positives = 174/265 (65%), Gaps = 9/265 (3%)
Query: 667 VAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDS 726
+A + TLFR +LAT ++D +M+ + F+Q A+ I K+++SKQ+ ELNP K +
Sbjct: 82 IAVVAERTTLFRSNTLATTLMDRYMKTTAQKFVQHAVGGVILKIMESKQSCELNPQKFEK 141
Query: 727 PDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVS 786
DA N E LL L I SIF+S ACP+ +RYLC C+Q AKW ++ + R V
Sbjct: 142 GADATENLEHLLGFLKDIIESIFSSTNACPRALRYLCACIQTDVKAKWKDDPVLPARAVG 201
Query: 787 GFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVN 846
GFIFLRLICPA++ PR + +V AP P A R+L+MVAK +QNLAN VEF +KEPYME +N
Sbjct: 202 GFIFLRLICPAVLNPRLFNIVSEAPSPVACRTLMMVAKAIQNLANQVEF-SKEPYMEAIN 260
Query: 847 PFILKNKERMVVFLDQLSNV---PDPGNSPPNSNVNFEIAKELATLHHICVAHLTELQGL 903
PFI+ NK RM+ FL L V P PG+ PP ++A++LA LH +CV HL ELQ L
Sbjct: 261 PFIVINKGRMIHFLTDLCLVNGPPTPGDVPP-----IDLARQLAALHQLCVTHLKELQQL 315
Query: 904 AKNQPAIRKLVTVTEMLTKHKQKYL 928
+ QP+++KL+ VTEML + K Y+
Sbjct: 316 STVQPSLKKLLGVTEMLNQRKIYYV 340
>UniRef50_Q54Y08 Cluster: NGAP-like protein; n=1; Dictyostelium
discoideum AX4|Rep: NGAP-like protein - Dictyostelium
discoideum AX4
Length = 877
Score = 196 bits (477), Expect = 3e-48
Identities = 105/302 (34%), Positives = 176/302 (58%), Gaps = 5/302 (1%)
Query: 591 EWGSLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRTDRQPLATSVLNTFA 650
++G +RL+++Y +E+V+P + Y PL +LL + + + L + + R+ ++ +++ F
Sbjct: 530 KFGDIRLKLKYSEEVVLPLQSYQPLLELLQQENLYTITLLGKVTK-HRESVSNNLIRVFE 588
Query: 651 ECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKL 710
+ G+ L + LT E+ + +FRG SLAT +D FM+ P+L I I+K+
Sbjct: 589 KTGKCLYLLKSLTDHEIDSTNNPDIIFRGNSLATKSVDLFMKLIGIPYLSQTIGPLIKKI 648
Query: 711 IDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAA 770
SK++ E++PTK++ +D N + LL + ++T +I +S CP P+R + +Q
Sbjct: 649 YSSKKSCEIDPTKLEKGEDIKKNCKNLLSWVKKMTTAILSSVNNCPGPLREVFKSIQDKV 708
Query: 771 VAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLA 830
V ++P + R VSGFIFLR CPA++ P+ + L+ P RSL+++AK LQNLA
Sbjct: 709 VQRYPKDEITRYTAVSGFIFLRFFCPAILAPKLFDLMPDHPGIKTTRSLILIAKTLQNLA 768
Query: 831 NLVEFGA-KEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNS-NVNFEIAKELAT 888
N VEFG KE +M+ +N F++ N E M F++ LS V P + PP + + KELA
Sbjct: 769 NQVEFGEYKEDFMKDMNRFVIDNMENMKSFINTLSTV--PADCPPGALQSPIILEKELAC 826
Query: 889 LH 890
L+
Sbjct: 827 LY 828
>UniRef50_Q8MLZ5 Cluster: Ras GTPase-activating protein gap-2; n=11;
Caenorhabditis|Rep: Ras GTPase-activating protein gap-2
- Caenorhabditis elegans
Length = 1207
Score = 162 bits (394), Expect = 3e-38
Identities = 126/493 (25%), Positives = 230/493 (46%), Gaps = 41/493 (8%)
Query: 418 LYQVHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCK 477
L+ VH S++E CF+L T+ + T E W+E LR P+ R Q +
Sbjct: 342 LHPVHPSIFEVPNCFRLAS---------TYYSCRTPLERAKWMENLRKTMNPR--RDQQR 390
Query: 478 VGRVSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDPHWXXXXXXXX 537
S ++W+ L A LPA+ + + + L A+T + D +
Sbjct: 391 RTENSMLIWI----LEAKGLPAKR--KYYCEMTLDKTLYAKTSSKARTDNVFWGENFEFM 444
Query: 538 MPPDVTSLTITV--HNTGKRGKESEVAELTIELANLANGEEIEEWYP------------- 582
M P + + +++ + K+ K++ + +TI + L++ +E WY
Sbjct: 445 MLPKIDEVCVSLFRESDSKKKKDTLIGYVTIGIDQLSSRSPVERWYTVNTSHSDSGTSRI 504
Query: 583 ---LVGMTPIGEWGSLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRT-DR 638
L G + E SLR++ R+ ++P Y+ L + L +P + L + D+
Sbjct: 505 ASALGGKSSSQESPSLRIKARWQSVHILPLRAYDNLLETLCYNYLPLCEQLEPVLNVRDK 564
Query: 639 QPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPF 698
+ LATS++ + E +L EV + + +FRG +LAT ++ FM+ +
Sbjct: 565 EDLATSLVRVMYKHNLAKEFLCDLIMKEVEKLDNDHLMFRGNTLATKAMESFMKLVADDY 624
Query: 699 LQAAISETIQKLIDSKQTAELNPTKMDSPDDAC--NNAEFLLMILDQITLSIFTSPEACP 756
L + +S+ I+ ++ + + E++P K+ + ++ N L+ ++ I + P
Sbjct: 625 LDSTLSDFIKTVLQCEDSCEVDPQKLGNVSNSSLEKNRALLMRYVEVAWTKILNNVHQLP 684
Query: 757 KPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQ 816
K +R + L+ A+ N + ++S IFLR +CPA++ P + LV P P
Sbjct: 685 KNLRDVFSALRCRLEAQ--NREALADTLISSSIFLRFLCPAILSPSLFNLVSEYPSPTNA 742
Query: 817 RSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNS 876
R+L ++AK LQNLAN +FG KEP+ME +N F+ + RM FL ++S+ G N+
Sbjct: 743 RNLTLIAKTLQNLANFSKFGGKEPHMEFMNEFVDREWHRMKDFLLRISSESKSG-PEKNA 801
Query: 877 NVNFEIAKELATL 889
+ + KEL+ +
Sbjct: 802 DAIVDAGKELSLI 814
>UniRef50_Q5VWQ8 Cluster: Disabled homolog 2-interacting protein;
n=88; Euteleostomi|Rep: Disabled homolog 2-interacting
protein - Homo sapiens (Human)
Length = 1189
Score = 161 bits (390), Expect = 1e-37
Identities = 129/494 (26%), Positives = 241/494 (48%), Gaps = 34/494 (6%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
VH S+ +++CF++ S + +A E W+E LR P + + R
Sbjct: 160 VHSSILGQDYCFEVTTS-----SGSKCFSCRSAAERDKWMENLRRAVHPNKDNSR----R 210
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHL-RVLLGAAPVARTRPRPSPDP-HWXXXXXXXXM 538
V +L L V + A LPA+ + +L + L ART + D W +
Sbjct: 211 VEHILKLWV--IEAKDLPAK---KKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNL 265
Query: 539 PPDVTSLTITVH---NTGKRGKE---SEVAELTIELANLANGEEIEEWYPLVGMTPIGEW 592
PP T+TVH T K+ K+ S + +++ A++A + +E+WYP+V P G
Sbjct: 266 PP---LRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPVVTPNPKGGK 322
Query: 593 GS---LRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALAD-LCRTDRQPLATSVLNT 648
G +R++ RY ++P E Y + + + AL L ++ +A+++++
Sbjct: 323 GPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHI 382
Query: 649 FAECGRGAELARELTCAEVAREGDHKTL-FRGASLATAVLDEFMRAHCKPFLQAAISETI 707
G+ + +L +EV R GD++ L FR +LAT ++E+++ + +LQ A+ E I
Sbjct: 383 LQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFI 442
Query: 708 QKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQ 767
+ L +S + E++P+K + D + L M + I S P+ ++ + +
Sbjct: 443 KALYESDENCEVDPSKCSAADLPEHQGN-LKMCCELAFCKIINSYCVFPRELKEVFASWR 501
Query: 768 RAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQ 827
+ ++ + + R++S +FLR +CPA++ P + L+Q P R+L ++AK Q
Sbjct: 502 QECSSRGRPD--ISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTARTLTLIAKVTQ 559
Query: 828 NLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELA 887
NLAN +FG+KE YM +N F+ M FL ++SN P+ ++ ++ +EL+
Sbjct: 560 NLANFAKFGSKEEYMSFMNQFLEHEWTNMQRFLLEISN-PETLSNTAGFEGYIDLGRELS 618
Query: 888 TLHHICVAHLTELQ 901
+LH + +++L+
Sbjct: 619 SLHSLLWEAVSQLE 632
>UniRef50_Q55CR5 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 2044
Score = 158 bits (384), Expect = 6e-37
Identities = 92/294 (31%), Positives = 158/294 (53%), Gaps = 6/294 (2%)
Query: 610 EEYNPLRQLLLEPGIPAVKALADLCRTDRQ-PLATSVLNTFAECGRGAELARELTCAEVA 668
E+YN L ++L P + + + +D+Q P S+ F + + EV
Sbjct: 1723 EQYNGLVEILASPSLQVAQCVVSAAPSDQQSPTIESISRIFESFNKIRPIIHSGIEQEVL 1782
Query: 669 REGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKM-DSP 727
+ TLFR + AT ++ F + P+LQ I+ ++++ID+ E++P K+ +
Sbjct: 1783 STANPSTLFRSNTTATKLMTAFTKLKGMPYLQKHITPLVREIIDNPNGYEVDPAKINEGS 1842
Query: 728 DDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSG 787
++ N L+ I ++ T +I S E P +R + LQ+ V K+P+ ++ V G
Sbjct: 1843 EELMTNMMNLIQICEKFTDAIIDSVENLPASLREISSYLQQEVVKKFPDNKYSS---VGG 1899
Query: 788 FIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNP 847
FIFLR +CP+++ P LV+ P P A R+L+++ K LQNLAN +EFG KE +M VN
Sbjct: 1900 FIFLRFLCPSILAPHTSGLVEEQPGPEATRALVLIGKVLQNLANGIEFGQKESFMIPVNR 1959
Query: 848 FILKNKERMVVFLDQLSNVPDPGNSPPNSNVN-FEIAKELATLHHICVAHLTEL 900
FI+ N R+ + D+L+NVP +S S + E+ K++ +H + V +L++L
Sbjct: 1960 FIIGNVTRLNNYFDKLTNVPMYTSSDSISTTSREEVQKDIRNIHLLIVKNLSKL 2013
>UniRef50_Q4TC99 Cluster: Chromosome undetermined SCAF7039, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF7039, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 978
Score = 151 bits (365), Expect = 1e-34
Identities = 129/494 (26%), Positives = 236/494 (47%), Gaps = 31/494 (6%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
VH SL +++CF++ T F + +A E W+E LR P + + +V
Sbjct: 25 VHSSLLGQDYCFEVTTST----GTKCF-SCRSAAERDKWMENLRRAVHPNKD-NSWRVEN 78
Query: 481 VSWVLWLRVRCLTAH-RLPARL--APRPHLRVLLGAAPVARTRPRPSPDPHWXXXXXXXX 537
V V + + L A R+ A L + R + L + ART + D +
Sbjct: 79 VLMVWVIEAKELPAKKRIVALLQFSSRYFCELCLDDSLYARTSCKLKTDNVFWGERFDFS 138
Query: 538 MPPDVTSLTITVHNTG----KRGKESEVAELTIELANLANGEEIEEWYPLVGMTPIGEWG 593
P ++++T+ ++ K+ K S V + I +A + + +E+WY + TP G
Sbjct: 139 SLPSISAVTLHLYKDTDRKRKKDKSSYVGLVNIPVAMVTGRQLVEKWYTV--STPSSSRG 196
Query: 594 S----LRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKAL-ADLCRTDRQPLATSVLNT 648
LR++ RY L++P E+Y + + + L L ++ LA ++++
Sbjct: 197 KSAPMLRIKARYQSILILPMEQYKEFAEYISSNYLLLCNTLEVSLSLRAKEELAAALVHI 256
Query: 649 FAECGRGAELARELTCAEVAREGDHKTL-FRGASLATAVLDEFMRAHCKPFLQAAISETI 707
G+ + +L +EV R D+ L FR +LAT ++E+++ + +LQ A+ E I
Sbjct: 257 LHSTGKAKDFLTDLMMSEVDRCRDNDQLIFRENTLATKSIEEYLKLIGQKYLQDALGEFI 316
Query: 708 QKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYL-CGCL 766
+ L +S + E++P++ + D + + A L M + I S + P+ ++ +
Sbjct: 317 KALYESDENCEVDPSRCATSDLSEHQAN-LRMCCELAFCKILDSYKVFPRELKEVFASWR 375
Query: 767 QRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCL 826
Q + + P+ + R++S +FLR +CPA++ P + L+Q P + R+L ++AK +
Sbjct: 376 QECSNRRRPD---ISERLISASLFLRFLCPAVMSPSLFDLMQEYPDERSARTLTLIAKVI 432
Query: 827 QNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKEL 886
Q LAN +FG KE YM +N F+ M FL ++SN D N + ++ +EL
Sbjct: 433 QTLANFSKFGTKEEYMLFMNDFVECQWSSMQRFLQEISNA-DGLNHMAGFDGYIDLGREL 491
Query: 887 ATLHHICVAHLTEL 900
++LH + LTEL
Sbjct: 492 SSLHTL----LTEL 501
>UniRef50_UPI0000F1E1DA Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 863
Score = 149 bits (362), Expect = 3e-34
Identities = 136/529 (25%), Positives = 237/529 (44%), Gaps = 41/529 (7%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
VH S+ +++CFQ++ + H F + A +R WIE LR P + C+
Sbjct: 95 VHSSILGEKYCFQVINSE----NNHCFGCTSAAERDR-WIEDLRRTAHPN--KDNCERTE 147
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRP-SPDPHWXXXXXXXXMP 539
S LW+ A LP + R + V L ART R W +P
Sbjct: 148 NSLCLWIN----EAKDLPPK--KRYYCEVHLDGTLFARTSSRAVGKSLFWGEFFELDNLP 201
Query: 540 PDVTSLTITVHN--TGKRGKESE-------VAELTIELANLANGEEIEEWYPLVGMTPIG 590
P VT +T+ + K+ + S + + + LA++ E+WY +V P G
Sbjct: 202 P-VTQITLHLFKGEDPKKKRHSRDDATLHPLGSVALPLADIKGRAYQEKWYRIVAYKPPG 260
Query: 591 E---------WGSLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRT-DRQP 640
S+R++ ++ ++P E Y + + + +L L +++
Sbjct: 261 TSTAKDSVELQASIRVKAKFKNLKILPIERYKEFAEYVTVNYVDMCSSLEPLLNVREKEE 320
Query: 641 LATSVLNTFAECGRGAELARELTCAEVAREGDHKTL-FRGASLATAVLDEFMRAHCKPFL 699
LA ++++ G+ E +L AEV R G+++ L FR +LAT +DE+M+ + +L
Sbjct: 321 LAGALVHVLQSIGKAKEFLIDLGSAEVQRLGENEALIFRENTLATKAIDEYMKLVGQKYL 380
Query: 700 QAAISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPV 759
+ + I +L + + E++P K SP D N L + + I E+ P +
Sbjct: 381 IDTLGDFIARLYNGGENCEVDPLKC-SPSDLPINQRHLKETCEDVVKRITDMQESFPAEL 439
Query: 760 RYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSL 819
+ + ++ + R++S +FLR +CPA++ P + L Q P + R+L
Sbjct: 440 NDIFSSWVSDCEDR--GQQDIGQRLISASLFLRFLCPAILSPSLFGLTQPYPETNTLRTL 497
Query: 820 LMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVN 879
+ AK +QNLAN FG KE YM +N F+ ++ E M FL ++SN P+ + +
Sbjct: 498 TLTAKVIQNLANFTLFGEKEEYMFFMNDFLTQHWEPMRDFLQKVSN-PESEITMSRFDGY 556
Query: 880 FEIAKELATLHHICVAHLTEL-QGLAKN-QPAIRKLVTVTEMLTKHKQK 926
++ LA LH++ V ++ + Q N P R L +TE L Q+
Sbjct: 557 VDLPLRLAVLHNLLVDIISVMKQDQIDNLHPLPRILNQITEFLGHDAQQ 605
>UniRef50_Q54RT3 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 608
Score = 142 bits (345), Expect = 3e-32
Identities = 87/302 (28%), Positives = 152/302 (50%), Gaps = 9/302 (2%)
Query: 602 MQELVMPREE--YNPLRQLLLEPGIPAVKALADLCRTDRQPLATSVLNTFAECGRGAELA 659
+ EL +EE YN L Q+ P + V A+ +D++ + ++ + +
Sbjct: 284 LYELSREKEENKYNELVQIFSSPDLAVVNAICLSAGSDQEAILEDLVRILDAHKQTLPII 343
Query: 660 RELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAEL 719
+ EV +TLFRG S AT ++ F R +P+L A + + KL+ EL
Sbjct: 344 KLGITKEVQSTSSAQTLFRGNSTATKLMTAFTRMTGRPYLVATLKPIVDKLLKDSSGYEL 403
Query: 720 NPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERF 779
+P K + + N E L I + +I+ S ++CP P R + LQ+ V +P +
Sbjct: 404 DPEKTSNTE---GNVERLSQICQEFLYAIYNSLDSCPLPFREMANHLQKEVVKVFPESKH 460
Query: 780 VRTRVVSGFIFLRLICPALVEPRAWTLVQRAP-PPHAQRSLLMVAKCLQNLANLVEFGAK 838
V GFIFLR CP ++ P + A A+R+L++V+K LQN+AN + FG+K
Sbjct: 461 TS---VGGFIFLRFFCPCILSPDTCGVSDSASLTMEARRALILVSKTLQNVANGITFGSK 517
Query: 839 EPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHICVAHLT 898
E YM+ +N F+ N E FLD+++ +P + P S+++ + +L ++H + + +L
Sbjct: 518 ETYMKDMNGFLESNMEGCKDFLDRIAEMPSNTDYQPLSSISEVKSNQLPSIHKLLIKNLE 577
Query: 899 EL 900
++
Sbjct: 578 KI 579
>UniRef50_UPI0000DB6EB0 Cluster: PREDICTED: similar to CG32560-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to
CG32560-PA - Apis mellifera
Length = 1482
Score = 141 bits (342), Expect = 7e-32
Identities = 121/514 (23%), Positives = 225/514 (43%), Gaps = 26/514 (5%)
Query: 408 KGLIDLSCAYLYQVHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLC 467
+ + + A + +H SL + CFQ+ P + + TA E W+ +LR
Sbjct: 366 QAVTSMDLAAVTPLHPSLLGRPHCFQVT----PSTGGPKYFSCRTAHERDQWLHSLRKSV 421
Query: 468 VPQQARHQCKVGRVSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDP 527
P Q + S +WL L A +PA+ R V L + ART + D
Sbjct: 422 QPDA--EQTRRTDNSLQIWL----LEAKGVPAK--KRYFCEVCLDSTLYARTTAKLKADL 473
Query: 528 HWXXXXXXXXMPPDVTSLTITVHNTGKRGKESE----VAELTIELANLANGEEIEEWYPL 583
+ P V ++ + ++ R K+ + + ++I + N+ + E+WY +
Sbjct: 474 CFWGEHFDFHHLPSVNTIQVNLYREADRKKKRDKNVLIGSVSIPVHNVTSRYLTEKWYTV 533
Query: 584 VG-MTPIGEWGSLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRTD-RQPL 641
VG P+ E +LR++ R+ ++P + Y + L + L + ++ +
Sbjct: 534 VGDKGPLKEPPALRVKCRFQSVDILPVQVYQEFLEYLKTDYASLCEKLEPVIGVKAKEDI 593
Query: 642 ATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQA 701
AT+++ + + +L ++ R D + FRG SLAT ++ +++ +LQ
Sbjct: 594 ATALVAVMQREKKAPQFLADLVMMDIHRIDDERLTFRGNSLATKAMEAYLKLTGDRYLQE 653
Query: 702 AISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRY 761
+ ++ ++ E++P K+ S + L ++ I S P +R
Sbjct: 654 TLGAVVRGAVEGGD-CEVDPLKVASVAALHKQQQNLRNAVELAWSRILASHAHFPLELRE 712
Query: 762 LCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLM 821
C + R +A E + ++S IFLR +CPA++ P + + P A R+L +
Sbjct: 713 -CFRIFRERLADMGRED-IADNLISASIFLRFLCPAILSPSLFNITHEYPNEKAARNLTL 770
Query: 822 VAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNF- 880
VAK LQ LAN F KE +ME +N + + M FL QL + P P ++P N+++ F
Sbjct: 771 VAKTLQTLANFTRFQGKENFMEFMNDLLEREAPSMKNFL-QLISSPLPKDAPANNSLEFD 829
Query: 881 ---EIAKELATLHHICVAHLTELQGLAKNQPAIR 911
++ K+L+ LH + L + + + P R
Sbjct: 830 GYIDLGKQLSLLHALLRESLVTITSFSSSLPPSR 863
>UniRef50_O95294 Cluster: RasGAP-activating-like protein 1; n=25;
Euteleostomi|Rep: RasGAP-activating-like protein 1 -
Homo sapiens (Human)
Length = 804
Score = 140 bits (340), Expect = 1e-31
Identities = 124/417 (29%), Positives = 195/417 (46%), Gaps = 41/417 (9%)
Query: 490 RCLTAHRLPAR-LAPR-------PHLRVLLGAAPVARTRPRPSPDPHWXXXXXXXXMPPD 541
RCL H L AR LAPR P RV G+ + + + + PHW MP
Sbjct: 133 RCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHWDEVLELREMPGA 192
Query: 542 VTSLTITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPI-----GEWGSLR 596
+ L + + + GK + + L + + W+ L+ G G+LR
Sbjct: 193 PSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQ-KPPKGWFRLLPFPRAEEDSGGNLGALR 251
Query: 597 LRIRYMQELVMPREEYNPLRQLLLEPGI-PA-------VKALADLCRTD-RQPLATSVLN 647
+++R +++ V+P + Y PL +LL+E PA + L +L D RQ LAT ++
Sbjct: 252 VKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGDCRQDLATKLVK 311
Query: 648 TFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETI 707
F G LT EVAR D TLFR SLA+ +++FM+ P+L + I
Sbjct: 312 LFLGRGLAGHFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGMPYLHEVLKPVI 371
Query: 708 QKLIDSKQTAELNPTKMD-------SPDDACNNAE-------FLLMILDQITLSIFTSPE 753
++ + K+ EL+P KMD S A + + L L I +I S
Sbjct: 372 SRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLGPIVDAIVGSVG 431
Query: 754 ACPKPVRYLCGCLQRAAVAKWP--NERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAP 811
CP +R L R ++P + V+ +SGF+FLR PA++ P+ + L +
Sbjct: 432 RCPPAMRLAFKQLHRRVEERFPQAEHQDVKYLAISGFLFLRFFAPAILTPKLFDLRDQHA 491
Query: 812 PPHAQRSLLMVAKCLQNLANL-VEFG-AKEPYMEVVNPFILKNKERMVVFLDQLSNV 866
P RSLL++AK +Q++ NL + G KE +M ++PF+L+ R+ FLD+L +V
Sbjct: 492 DPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVRDFLDRLVDV 548
>UniRef50_UPI00015B5738 Cluster: PREDICTED: similar to synaptic ras
gtpase activating protein, syngap; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to synaptic ras
gtpase activating protein, syngap - Nasonia vitripennis
Length = 1551
Score = 138 bits (334), Expect = 6e-31
Identities = 114/489 (23%), Positives = 213/489 (43%), Gaps = 21/489 (4%)
Query: 408 KGLIDLSCAYLYQVHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLC 467
+ + + A + +H SL + CFQ+ P + + TA E W+ +LR
Sbjct: 410 QAVTSMDLAAVTPLHPSLLNRPHCFQVT----PSNGGPKYFSCRTAHEREQWMHSLRKSV 465
Query: 468 VPQQARHQCKVGRVSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDP 527
P+ Q + S +WL L A +PA+ R V L + ART + D
Sbjct: 466 QPEA--EQTRRTDNSLQIWL----LEAKGVPAK--KRYFCEVCLDSTLYARTTAKLKADL 517
Query: 528 HWXXXXXXXXMPPDVTSLTITVHNTGKRGKESE----VAELTIELANLANGEEIEEWYPL 583
+ P V ++ + ++ R K+ + + + I + N+ + E+WYP+
Sbjct: 518 CFWGERFDFHHLPAVNTIQVNLYREADRKKKRDKNVLIGSVNIPVNNVTSRYLTEKWYPV 577
Query: 584 VG-MTPIGEWGSLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRTD-RQPL 641
VG P+ E +LR++ R+ ++P + Y+ + L + L + ++ +
Sbjct: 578 VGDKGPLKEPPALRVKCRFQSVDILPVQVYSEFLEYLKTDYAALCEKLEPVIGVKAKEDI 637
Query: 642 ATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQA 701
AT+++ R + +L ++ R D + FRG SLAT ++ +++ +LQ
Sbjct: 638 ATALVAVMQREKRAPQFLADLVMMDIHRIDDERLTFRGNSLATKAMEAYLKLTGDRYLQE 697
Query: 702 AISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRY 761
+ ++ ++ E++P K+ S + L ++ I S P +R
Sbjct: 698 TLGPVVRGAVEGGD-CEVDPLKVASVAALHKQQQNLRAAVELAWSRILASHSHFPVELRE 756
Query: 762 LCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLM 821
C + R + + E ++S IFLR +CPA++ P + + P A R+L +
Sbjct: 757 -CFRIFRERLKEMGREDMA-DNLISASIFLRFLCPAILSPSLFNITHEYPNEKAARNLTL 814
Query: 822 VAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFE 881
VAK LQ LAN F KE +ME +N + + M FL +S+ + N+ + +
Sbjct: 815 VAKTLQTLANFTRFQGKENFMEFMNDVLEREAPSMKTFLQLISSSKETQNNLMEYDGYID 874
Query: 882 IAKELATLH 890
+ K+L+ LH
Sbjct: 875 LGKQLSLLH 883
>UniRef50_Q14644 Cluster: Ras GTPase-activating protein 3
(GAP1(IP4BP)); n=46; Deuterostomia|Rep: Ras
GTPase-activating protein 3 (GAP1(IP4BP)) - Homo sapiens
(Human)
Length = 834
Score = 138 bits (333), Expect = 8e-31
Identities = 99/322 (30%), Positives = 155/322 (48%), Gaps = 18/322 (5%)
Query: 561 VAELTIELANLANGEEIEEWYPLV----GMTPI--GEWGSLRLRIRYMQELVMPREEYNP 614
+ EL I L L E WY L G + + GSLRL + Y ++ V + Y+P
Sbjct: 243 LGELRIPLKVLRQSSSYEAWYFLQPRDNGSKSLKPDDLGSLRLNVVYTEDHVFSSDYYSP 302
Query: 615 LRQLLL-----EP-GIPAVKALADLCRTDRQPLATSVLNTFAECGRGAELARELTCAEVA 668
LR LLL EP A L ++CR ++Q A ++ F GR + AEV
Sbjct: 303 LRDLLLKSADVEPVSASAAHILGEVCR-EKQEAAVPLVRLFLHYGRVVPFISAIASAEVK 361
Query: 669 REGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPD 728
R D T+FRG SLA+ +DE M+ +L + I+++ S + E++P K+ +
Sbjct: 362 RTQDPNTIFRGNSLASKCIDETMKLAGMHYLHVTLKPAIEEICQSHKPCEIDPVKLKDGE 421
Query: 729 DACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGF 788
+ NN E L +D++ +I S +CP + + L+ AA ++ ++ VR VS F
Sbjct: 422 NLENNMENLRQYVDRVFHAITESGVSCPTVMCDIFFSLREAAAKRFQDDPDVRYTAVSSF 481
Query: 789 IFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGA---KEPYMEVV 845
IFLR PA++ P + L P R+L +++K +Q L +L + + KE YM
Sbjct: 482 IFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTVQTLGSLSKSKSASFKESYMATF 541
Query: 846 NPFILKNKERMVV--FLDQLSN 865
F + K V FLD +S+
Sbjct: 542 YEFFNEQKYADAVKNFLDLISS 563
>UniRef50_Q96PV0 Cluster: Ras GTPase-activating protein SynGAP;
n=28; Euteleostomi|Rep: Ras GTPase-activating protein
SynGAP - Homo sapiens (Human)
Length = 1343
Score = 136 bits (330), Expect = 2e-30
Identities = 137/535 (25%), Positives = 239/535 (44%), Gaps = 53/535 (9%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
VH S+ +EFCF++ + T F A +A E WIE L+ P + + R
Sbjct: 209 VHSSILGQEFCFEVTTSS----GTKCF-ACRSAAERDKWIENLQRAVKPNKDNSR----R 259
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRP---SPDPHWXXXXXXXX 537
V VL L + + A LP + R + + L ART +P S D +
Sbjct: 260 VDNVLKLWI--IEARELPPK--KRYYCELCLDDMLYARTTSKPRSASGDTVFWGEHFEFN 315
Query: 538 MPPDVTSLTITVHNTG----KRGKESEVAELTIELANLANGEEIEEWYPLV--------- 584
P V +L + ++ K+ K V +T+ +A LA E+WYP+
Sbjct: 316 NLPAVRALRLHLYRDSDKKRKKDKAGYVGLVTVPVATLAGRHFTEQWYPVTLPTGSGGSG 375
Query: 585 GMTPIGEWGS--------------LRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKAL 630
GM G GS +RL+ RY ++P E Y + + L
Sbjct: 376 GMGSGGGGGSGGGSGGKGKGGCPAVRLKARYQTMSILPMELYKEFAEYVTNHYRMLCAVL 435
Query: 631 ADLCRTD-RQPLATSVLNTFAECGRGAELARELTCAEVAR--EGDHKTLFRGASLATAVL 687
++ +A+++++ G+ + ++ +EV R E +H +FR +LAT +
Sbjct: 436 EPALNVKGKEEVASALVHILQSTGKAKDFLSDMAMSEVDRFMEREH-LIFRENTLATKAI 494
Query: 688 DEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLS 747
+E+MR + +L+ AI E I+ L +S++ E++P K + A + A L M +
Sbjct: 495 EEYMRLIGQKYLKDAIGEFIRALYESEENCEVDPIKCTASSLAEHQAN-LRMCCELALCK 553
Query: 748 IFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLV 807
+ S P+ ++ + + + + + R++S +FLR +CPA++ P + L+
Sbjct: 554 VVNSHCVFPRELKEVFASWRLRCAERGRED--IADRLISASLFLRFLCPAIMSPSLFGLM 611
Query: 808 QRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVP 867
Q P R+L ++AK +QNLAN +F +KE ++ +N F+ M FL ++SN+
Sbjct: 612 QEYPDEQTSRTLTLIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGSMQQFLYEISNLD 671
Query: 868 DPGNSPPNSNVNFEIAKELATLHHICVAHLTEL--QGLAKNQPAIRKLVTVTEML 920
NS ++ +EL+TLH + L +L + L K P R L ++ L
Sbjct: 672 TLTNSSSFEGY-IDLGRELSTLHALLWEVLPQLSKEALLKLGPLPRLLNDISTAL 725
>UniRef50_A7RYE3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 828
Score = 136 bits (329), Expect = 3e-30
Identities = 85/288 (29%), Positives = 145/288 (50%), Gaps = 13/288 (4%)
Query: 590 GEWGSLRLRIRYMQELVMPREEYNPLRQLLLE----PGIPAVKA--LADLCRTDRQPLAT 643
G GSLRL++ Y ++ V P Y PLR+ +LE + A L+++ + D+ A
Sbjct: 271 GSIGSLRLKVCYTEDYVFPSSYYEPLREAILEIEGHKDVTTTPAYILSEIVK-DKLTAAR 329
Query: 644 SVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAI 703
+++ F + + + + EV D TLFRG SL T +DEFM+ +L I
Sbjct: 330 ALVRVFTHHNKVVDFIKAVVDHEVNTTADCNTLFRGNSLGTKAIDEFMKHAGMQYLHETI 389
Query: 704 SETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLC 763
+ ++ + ++ E++P+++ D N L ++++ +I S ACP + +
Sbjct: 390 KTLVDEIYEERKCCEIDPSRLRDGDSLPQNLANLQGYVNKLCAAITCSAMACPTAMSKVF 449
Query: 764 GCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVA 823
++ +AV ++ +E VR VSGF+FLR PA++ P+ + + P P R+L + +
Sbjct: 450 VTIRESAVQRFSDEPDVRYTAVSGFVFLRFFAPAILNPKLFQMRNEHPDPLVARTLTLAS 509
Query: 824 KCLQNLANLVEF----GAKEPYMEVVNPFILKNKERMVV--FLDQLSN 865
K +Q+L NLV KEPYME + IL V FLD +S+
Sbjct: 510 KAIQSLGNLVSSVICGQVKEPYMESLKAMILDQDHITAVKRFLDAISS 557
>UniRef50_A7SKG2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1037
Score = 135 bits (326), Expect = 6e-30
Identities = 119/489 (24%), Positives = 218/489 (44%), Gaps = 30/489 (6%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
+H S+ ++ CFQ+ + + + +A E W+ +++ P AR Q
Sbjct: 12 IHPSILHRQHCFQVTSP-----TEVKYFSCRSAQELNKWVNSIKKSIQP--ARDQQNRMD 64
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDPHWXXXXXXXXMPP 540
+S +W+ A P + R +LL ART + D +
Sbjct: 65 ISLSVWV-CEAKGAMTTPKK---RYFCELLLDKMLYARTTSKTKVDTLFWGENFSFDDLL 120
Query: 541 DVTSLTITVHNT----GKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPIG--EWGS 594
D++++T+ ++ K+ K V + I + +L + +E+E+W+P V MT G + GS
Sbjct: 121 DLSTITVNIYKDLEAKNKKEKRKLVGTVNIPVRDLDSSQEVEKWFP-VDMTTKGNADSGS 179
Query: 595 LRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRTD-RQPLATSVLNTFAECG 653
+RL+I+Y + ++P YN + L + L + + +A +L G
Sbjct: 180 IRLKIKYQKIHILPLTTYNEMLSYLSNNYMHLCGTLESAVSSKVKDEIAGVILRVLQPVG 239
Query: 654 RGAELARELTCAEVAREG--DHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLI 711
+ E ++ EV R G D +FRG S AT +D +M+ + + + +Q +
Sbjct: 240 KAQEFLVDIVMDEVNRLGSADENLVFRGNSFATKAMDTYMKMVGE---SETLGDFVQSVY 296
Query: 712 DSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAV 771
+ E++P K + +N E L ++ I S P ++ ++ ++
Sbjct: 297 AMSEDCEVDPAKSVN-GSIQSNQENLKAFAEKAWNHILCSSCIFPCDLQDTFHEFRQRSI 355
Query: 772 AKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLAN 831
R + +++S IFLR +CPA++ P + LVQ P R+L ++AK +QNLAN
Sbjct: 356 N---GSRDLSNKLISASIFLRFLCPAIMSPSLFHLVQEYPNERILRTLTLIAKVIQNLAN 412
Query: 832 LVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHH 891
+FG KE YM +N F+ ++M F+ +S+ P G + + +ELA L++
Sbjct: 413 FTKFGGKEDYMGFMNDFVQNEFDKMREFVATISS-PSVGRE-NRFEGSIDHGRELALLYN 470
Query: 892 ICVAHLTEL 900
I L L
Sbjct: 471 ILKDQLGRL 479
>UniRef50_Q8WZX6 Cluster: Related to NEUROFIBROMIN; n=4;
Sordariomycetes|Rep: Related to NEUROFIBROMIN -
Neurospora crassa
Length = 2735
Score = 135 bits (326), Expect = 6e-30
Identities = 98/327 (29%), Positives = 161/327 (49%), Gaps = 12/327 (3%)
Query: 610 EEYNPLRQLLLEPGIPAVKALADLCRTDR-QPLATSVLNTFAECGRGAELARELTCAEVA 668
E+Y+ L LL A+ A+ +C + L ++L+ + G+ L L E+
Sbjct: 1275 EKYDELLSLLTTDTTLAM-AMGAVCPSHEVDELTIALLSIYESRGQSFVLLEALIKQEIE 1333
Query: 669 REGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQ--TAELNPTKMDS 726
+ L R + +AT +L + + +L+A + + + +L+ + + EL+PT++ S
Sbjct: 1334 ETENESELLRRSCVATKMLSIYAKWKGAGYLKATLQKVLDRLMQTSKDLNLELDPTRVSS 1393
Query: 727 PDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVS 786
P++ NA L ++ + I S P R +C + A + ++ ++ V
Sbjct: 1394 PEELQKNALQLEIVANVFIDDICASSARIPPSFRKICSIIAAAVMPRFSEAKYT---AVG 1450
Query: 787 GFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVN 846
FIFLR CPA+V P LV AP +R LL++AK +QNLAN V FGAKEP+M +N
Sbjct: 1451 AFIFLRFFCPAIVAPEVEGLVATAPSKEMRRGLLLIAKVIQNLANNVLFGAKEPFMFPLN 1510
Query: 847 PFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHICVAHLTEL-QGLAK 905
F+ KN R+ FL ++S P+ PNS+ +F+ +LH I H ++ Q LA
Sbjct: 1511 DFLTKNIYRVTTFLREISVEPET-MERPNSDESFDFG-SCVSLHRILYDHWDQVRQRLAS 1568
Query: 906 NQPAIRKLVTVTEMLTKHKQKYLEMIR 932
+ R LV T+ K LE +R
Sbjct: 1569 IER--RDLVRSPCEPTRGKPNLLEPLR 1593
>UniRef50_A6R6N8 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 1390
Score = 134 bits (323), Expect = 1e-29
Identities = 70/211 (33%), Positives = 118/211 (55%), Gaps = 3/211 (1%)
Query: 660 RELTCAEVAREG--DHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTA 717
RE+ ++ R + LFRG SL T LD MR + +L+ I ++ + +S
Sbjct: 907 REVLVRDLGRSATVEANLLFRGNSLLTKALDLHMRRLGQEYLEETIGSKLRDIDESDPDC 966
Query: 718 ELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNE 777
E++P ++ P+D N L+++ + SI S CP +R++ ++ A ++ +
Sbjct: 967 EIDPNRVQRPEDLERNWRNLIILTSSVWTSIAASSARCPAELRHIFRHIRACAEDRYGDF 1026
Query: 778 -RFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFG 836
R V VSGF+FLR CPA++ P+ + L++ P P AQR+L ++AK LQ LANL FG
Sbjct: 1027 LRSVTYSSVSGFLFLRFFCPAILNPKLFGLLKEHPRPRAQRTLTLIAKALQGLANLTTFG 1086
Query: 837 AKEPYMEVVNPFILKNKERMVVFLDQLSNVP 867
KEP+ME +N F++ ++ F+D + ++P
Sbjct: 1087 NKEPWMEPMNKFLISHRVEFKEFVDSICSIP 1117
>UniRef50_Q9P412 Cluster: GTPase activating protein; n=1; Blumeria
graminis f. sp. hordei|Rep: GTPase activating protein -
Erysiphe graminis subsp. hordei (Grass mildew) (Blumeria
graminissubsp. hordei)
Length = 1047
Score = 131 bits (316), Expect = 1e-28
Identities = 70/193 (36%), Positives = 113/193 (58%), Gaps = 1/193 (0%)
Query: 676 LFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACNNAE 735
LFRG SL T LD MR K +L+ +SE I K+ E++P+++ + +D+ N
Sbjct: 624 LFRGNSLLTQALDLHMRRVGKEYLEDVLSEKILKINSMNPDCEVDPSRISNSNDSDKNWT 683
Query: 736 FLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNE-RFVRTRVVSGFIFLRLI 794
+ + ++ SI +S CP +R + ++ A ++ N R V VSGF+FLR
Sbjct: 684 LIFSLTTEVWDSIASSATRCPPELRQILKYIRAVAEDRYGNFLRTVTYTSVSGFLFLRFF 743
Query: 795 CPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKE 854
CPAL+ P+++ L++ P P AQR+L ++AK LQ LANL +FG KE +ME +N F+ +++
Sbjct: 744 CPALLNPKSFGLLRDHPQPKAQRTLTLIAKSLQALANLSKFGKKEAWMERMNQFLATHRQ 803
Query: 855 RMVVFLDQLSNVP 867
M F+D + +P
Sbjct: 804 GMKDFIDMICAIP 816
>UniRef50_A2QLJ8 Cluster: Contig An06c0090, complete genome; n=1;
Aspergillus niger|Rep: Contig An06c0090, complete genome
- Aspergillus niger
Length = 1082
Score = 131 bits (316), Expect = 1e-28
Identities = 72/217 (33%), Positives = 120/217 (55%), Gaps = 3/217 (1%)
Query: 660 RELTCAEVAREG--DHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTA 717
RE+ ++ R + LFRG SL T LD MR K +L+ I E ++ + ++
Sbjct: 612 REVLVRDMGRTATVEANLLFRGNSLLTKALDYHMRRLGKEYLEETIGERLRDIDETDPEC 671
Query: 718 ELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNE 777
E++P+++ DD N L+ + + SI +S CP +R + ++ A ++ +
Sbjct: 672 EVDPSRVHRSDDLDRNWRNLVSLSTGVWKSIASSASRCPAELRLIFRHIRACAEDRYGDF 731
Query: 778 -RFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFG 836
R V VSGF+FLR CPA++ P+ + L++ P P AQR+L ++AK LQ LAN+ FG
Sbjct: 732 LRSVTYSSVSGFLFLRFFCPAILNPKLFGLLKDHPRPRAQRTLTLIAKALQGLANMTTFG 791
Query: 837 AKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSP 873
+KEP+ME +N F++ N+ F+D + +P +P
Sbjct: 792 SKEPWMEPMNKFLVSNRADFKQFVDSICAIPADRPAP 828
>UniRef50_A1CU76 Cluster: GTPase activating protein (BUD2/CLA2),
putative; n=7; Eurotiomycetidae|Rep: GTPase activating
protein (BUD2/CLA2), putative - Aspergillus clavatus
Length = 1267
Score = 131 bits (316), Expect = 1e-28
Identities = 72/217 (33%), Positives = 121/217 (55%), Gaps = 3/217 (1%)
Query: 660 RELTCAEVAREG--DHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTA 717
RE+ ++ R + LFRG SL T LD MR K +L+ I E ++++ +S
Sbjct: 794 REVLVRDLGRTATVEANLLFRGNSLLTKALDLHMRRLGKEYLEETIGERLREIDESDPDC 853
Query: 718 ELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNE 777
E++P+++ DD N L+ + + SI +S CP +R + ++ A ++ +
Sbjct: 854 EVDPSRVHRADDLERNWRSLIALTTSVWKSIASSASRCPPELRLIFRHIRACAEDRYGDF 913
Query: 778 -RFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFG 836
R V VSGF+FLR CPA++ P+ + L++ P P AQR+L ++AK LQ LAN+ FG
Sbjct: 914 LRTVTYSSVSGFLFLRFFCPAILNPKLFGLLKDHPRPRAQRTLTLIAKALQGLANMTTFG 973
Query: 837 AKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSP 873
+KEP+ME +N F++ ++ F+D + +P +P
Sbjct: 974 SKEPWMEPMNKFLVGSRLEFRQFVDSICAIPADRPTP 1010
>UniRef50_UPI000156148A Cluster: PREDICTED: hypothetical protein;
n=1; Equus caballus|Rep: PREDICTED: hypothetical protein
- Equus caballus
Length = 785
Score = 129 bits (312), Expect = 3e-28
Identities = 90/297 (30%), Positives = 150/297 (50%), Gaps = 6/297 (2%)
Query: 595 LRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRTDRQPLATSVLNTFAECGR 654
LR R R ++ELV R+ + +LL G+ L ++ LA +++ R
Sbjct: 401 LRKRARRLRELVSFRKYKQVVFLILLYKGLGGGLE-CKLSAQAKEELAAAMVRLLQATDR 459
Query: 655 GAELARELTCAEVAREGDHKTL-FRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDS 713
L +L AE+AR G + L FR +LAT +DE+M+ + +LQ + + +++L S
Sbjct: 460 AQALVTDLGTAELARSGGREALLFRENTLATKAIDEYMKLVAQDYLQETLGQIVRRLCAS 519
Query: 714 KQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAK 773
+ E++P+K S + + A L +++ SI S + P + + + A A+
Sbjct: 520 SEDCEVDPSKCQSAELPQHQAR-LQNSCEEVFQSIVRSHDWFPAELGTVFSGWREACKAR 578
Query: 774 WPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLV 833
+ R+V +FLRL+CPA++ P + L P P R+L ++AK +QNLAN
Sbjct: 579 --GSEALGPRLVCASLFLRLLCPAILAPSLFGLAPEHPAPGPARALTLIAKVIQNLANRA 636
Query: 834 EFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLH 890
FG KE YM +N F+ + M FLDQ++ V D +P + ++A +LA LH
Sbjct: 637 PFGEKEAYMTFMNSFLEDHGPAMQRFLDQVAMV-DVDAAPSGYQGSSDLALQLAVLH 692
>UniRef50_A4RD11 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 2487
Score = 126 bits (305), Expect = 2e-27
Identities = 79/259 (30%), Positives = 129/259 (49%), Gaps = 6/259 (2%)
Query: 610 EEYNPLRQLLLEPGIPAVKALADLCRTDRQPLATSVLNTFAECGRGAELARELTCAEVAR 669
E+Y+ L LL AV + ++ L ++LN F G EL L EV
Sbjct: 1179 EKYDKLLNLLTRDTTLAVAMSSSCPSSEVDELTIALLNIFERRGLSFELIEALIKQEVED 1238
Query: 670 EGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKL-IDSKQ-TAELNPTKMDSP 727
+ L R S+AT +L + + +L+A + + +++L + SK EL+P ++D
Sbjct: 1239 TENESELLRRTSVATKMLSVYAKWKGAAYLKATLQKVVERLMLTSKDLNLELDPQRVDQS 1298
Query: 728 DDACNNAEFLLMILDQITLS-IFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVS 786
+ N L I+ ++ + I S P R +C + A++ + ++ V
Sbjct: 1299 KEELNKNALQLRIVAKVFIEDICASKANIPDSFRKICSIISNTVTARFHDSKYT---AVG 1355
Query: 787 GFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVN 846
F+FLR CPA+V P LV + P +R LL++AK +QNLAN V FGAKEPYM +N
Sbjct: 1356 AFVFLRFFCPAIVAPEVEGLVNKQPTREMRRGLLLIAKIIQNLANNVLFGAKEPYMFPLN 1415
Query: 847 PFILKNKERMVVFLDQLSN 865
F+ +N ++ FL ++S+
Sbjct: 1416 DFLTQNIYKVTTFLREISD 1434
>UniRef50_Q178K3 Cluster: Synaptic ras gtpase activating protein,
syngap; n=1; Aedes aegypti|Rep: Synaptic ras gtpase
activating protein, syngap - Aedes aegypti (Yellowfever
mosquito)
Length = 1317
Score = 124 bits (298), Expect = 1e-26
Identities = 129/535 (24%), Positives = 224/535 (41%), Gaps = 40/535 (7%)
Query: 411 IDLSCAY---LYQVHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLC 467
IDLSC + VH S+ + CFQ+ R P + + + E WI +LR
Sbjct: 87 IDLSCIGAIGVVPVHASVLGRRHCFQV--RGGP--RGERYYSCGSRQERDLWIYSLRKSI 142
Query: 468 VPQQARHQCKVGRVSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDP 527
P A + + S +W+ A LP + + + L RT + +
Sbjct: 143 APN-AENTRRTDN-SLKMWV----YEAKALPPK--KKYFCEINLDKTLYGRTSVKLRTEL 194
Query: 528 HWXXXXXXXXMPPDVTSLTITVHNTG----KRGKESEVAELTIELANLANGEEIEEWYPL 583
+ PD+ +T+ V+ G KR K + V + I + + + E+WYP+
Sbjct: 195 LFWGEYFDFPDVPDINVITVNVYREGEKKKKRDKHALVGSVKIPIHEVTSRTFSEDWYPI 254
Query: 584 VG--MTPIGEWGS------LRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCR 635
+ I + S LR++ R+ ++P Y L E + L +
Sbjct: 255 ISDKHDSISKNSSKEPIPTLRIKCRFQSIDILPFGVYQDFMDYLKENYKKVCEMLEPVIG 314
Query: 636 TD-RQPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAH 694
++ + +++ G A ++ ++ R GD + FRG SLAT ++ F++
Sbjct: 315 VKAKEDIGQALVLLMHAQGMAAAFLTDVVALDLLRVGDQRLTFRGNSLATKSMEAFLKLT 374
Query: 695 CKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEA 754
+ +LQ +S I ++I S + E++P K + + L + SI S ++
Sbjct: 375 GEQYLQDTLSSPISEIISSDRDCEVDPLKANG--SLSRQQQALRNAVKTAWNSIADSSKS 432
Query: 755 CPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPH 814
P +R C R + E ++S IFLR +CPA++ P + + P
Sbjct: 433 FPTQLRD-CFSTFRERLQMLDREDMA-DNLISASIFLRFLCPAILSPSLFNITNELPSAR 490
Query: 815 AQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPP 874
A R+L +VAK LQ LAN F KE +ME +N F+ RM FL +S + N
Sbjct: 491 ATRNLTLVAKTLQTLANFTRFQGKENFMEFLNDFLENEAPRMKQFLHDISTRSE--NPMQ 548
Query: 875 NSNVNF----EIAKELATLHHICVAHLTELQGLAKNQPAIRKLVTVTEMLTKHKQ 925
S +++ + K+L+ LH + + +L A Q + L + E +T K+
Sbjct: 549 ESILDWAGYIDQGKQLSILHTLLAESIQKLP--ASKQIDLHPLPNILESITAAKE 601
>UniRef50_Q15283 Cluster: Ras GTPase-activating protein 2; n=14;
Eutheria|Rep: Ras GTPase-activating protein 2 - Homo
sapiens (Human)
Length = 849
Score = 123 bits (297), Expect = 2e-26
Identities = 81/299 (27%), Positives = 145/299 (48%), Gaps = 13/299 (4%)
Query: 545 LTITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLVGM------TPIGEWGSLRLR 598
+ I + N G ++ + E+ + + L + WY L + + GSLRL
Sbjct: 253 IRIDLWNNGNLVQDVFLGEIKVPVNVLRTDSSHQAWYLLQPRDNGNKSSKTDDLGSLRLN 312
Query: 599 IRYMQELVMPREEYNPLRQLLLE-PGIPAVKA-----LADLCRTDRQPLATSVLNTFAEC 652
I Y ++ V+P E Y PL+ LLL+ P + + A L+++CR D+ ++
Sbjct: 313 ICYTEDYVLPSEYYGPLKTLLLKSPDVQPISASAAYILSEICR-DKNDAVLPLVRLLLHH 371
Query: 653 GRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLID 712
+ A + ++ D T+FRG SLAT LDE M+ +L+ + + ++ D
Sbjct: 372 DKLVPFATAVAELDLKDTQDANTIFRGNSLATRCLDEMMKIVGGHYLKVTLKPILDEICD 431
Query: 713 SKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVA 772
S ++ E++P K+ D+ NN E L +D++ +I S +CP + + L++ A
Sbjct: 432 SSKSCEIDPIKLKEGDNVENNKENLRYYVDKLFNTIVKSSMSCPTVMCDIFYSLRQMATQ 491
Query: 773 KWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLAN 831
++PN+ V+ VS F+FLR A+V P + L P R+L +++K +Q L +
Sbjct: 492 RFPNDPHVQYSAVSSFVFLRFFAVAVVSPHTFHLRPHHPDAQTIRTLTLISKTIQTLGS 550
>UniRef50_Q54Q13 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1056
Score = 122 bits (295), Expect = 3e-26
Identities = 86/269 (31%), Positives = 133/269 (49%), Gaps = 16/269 (5%)
Query: 611 EYNPLRQLLLEPGIPAVKALADLCRTDRQPLATSV-----LNTFAE--CG-RGAELAREL 662
+Y+ + LLL P + V +L R+ + SV L F E C + + + +
Sbjct: 50 KYSDIIDLLLSPDLEIVSSLCSTTLV-RETVPNSVHISEYLIVFFEYHCNLKSSYILKWA 108
Query: 663 TCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPT 722
E+ + TLFRG S AT ++ F + + +L+ + + L + E++P
Sbjct: 109 IDKEIENTSNSATLFRGLSTATRLISAFYKRVGESYLKYLLQPFVIDLCSRNFSFEIDPE 168
Query: 723 KMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRT 782
K + N E L+ I Q+ I S + CP P+R + Q ++ + ++T
Sbjct: 169 KAGKGVNIQANLEKLITITQQLLDKILDSVDQCPLPIRQILNHTQEKVEKRF---KSMKT 225
Query: 783 RVVSGFIFLRLICPALVEPRAWTLVQR--APPPHAQRSLLMVAKCLQNLANLVEFGA--K 838
VV GFIFLR ICPA+V P A+ L+ R P +R L++V+K LQNLAN + FG+ K
Sbjct: 226 TVVGGFIFLRFICPAIVAPEAFGLIPREEEPTSETRRGLVLVSKLLQNLANEMPFGSGIK 285
Query: 839 EPYMEVVNPFILKNKERMVVFLDQLSNVP 867
E YM +N FI N R+ VF D L+ P
Sbjct: 286 EEYMSYLNDFITNNSTRIHVFFDSLAQDP 314
>UniRef50_UPI0000DB7F93 Cluster: PREDICTED: similar to RAS p21
protein activator 3; n=2; Endopterygota|Rep: PREDICTED:
similar to RAS p21 protein activator 3 - Apis mellifera
Length = 952
Score = 121 bits (292), Expect = 8e-26
Identities = 79/265 (29%), Positives = 134/265 (50%), Gaps = 13/265 (4%)
Query: 593 GSLRLRIRYMQELVMPREEYNPLRQLLLEP------GIPAVKALADLCRTDRQPLATSVL 646
GSLRL+I Y + V P Y+ LR LLL+ AV L ++ + + A ++
Sbjct: 293 GSLRLKIHYTADHVFPSAMYDRLRNLLLQSVNIQPITSSAVYILGEIV-SSKMEAAQPLV 351
Query: 647 NTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISET 706
G+ + R L E+++ D T+FRG +L + ++DE MR +L + +
Sbjct: 352 RVLVHYGQLVSVMRALASHEISKLTDPTTIFRGNTLVSKMMDEGMRLAGLHYLHSTLRPA 411
Query: 707 IQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCL 766
++++ K++ E++PT++ + N L ++++ +I TS CP + + CL
Sbjct: 412 MKQVFLEKKSCEIDPTRVKDANTIQTNLTNLKEYVERVFTAITTSGVRCPSLMCEMFWCL 471
Query: 767 QRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCL 826
+ A +P + VR V+SGFIFLR PA++ PR + + R+L +++K +
Sbjct: 472 KELAATHFPKNKEVRYSVISGFIFLRFFAPAILGPRLFDITTEQIDSQTNRTLTLISKTI 531
Query: 827 QNLANLVEF--GA----KEPYMEVV 845
Q+L NLV GA KE YME V
Sbjct: 532 QSLGNLVSCRGGAGSVCKEEYMECV 556
>UniRef50_Q8T498 Cluster: Probable Ras GTPase-activating protein;
n=5; Eukaryota|Rep: Probable Ras GTPase-activating
protein - Drosophila melanogaster (Fruit fly)
Length = 1556
Score = 121 bits (291), Expect = 1e-25
Identities = 128/521 (24%), Positives = 220/521 (42%), Gaps = 47/521 (9%)
Query: 411 IDLSCAY---LYQVHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLC 467
IDLSC + VH+S+ + CFQ+ R P + + + E WI +LR
Sbjct: 211 IDLSCTGAVGVAPVHQSVLGRRHCFQV--RGGP--RGERYYSCGSRQERDLWIYSLRKSI 266
Query: 468 VPQQARHQCKVGRVSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDP 527
P A H + S +W+ A LP + R + L RT + D
Sbjct: 267 APN-AEHTRRTDN-SLKMWV----YEAKNLPPK--KRYFCELQLDKTLYGRTSVKLQTDL 318
Query: 528 HWXXXXXXXXMPPDVTSLTITVHNT----GKRGKESEVAELTIELANLANGEEIEEWYPL 583
+ P++ +T+ V KR K V + I + ++ + E+WYP+
Sbjct: 319 LFWGEHFDFPDIPEINVITVNVFREVDKKKKRDKYQFVGSVKIPVHDVTSRLPCEQWYPI 378
Query: 584 V--------GMTPIG---------EWGSLRLRIRYMQELVMPREEYNPLRQLLLEPGIPA 626
+ G T G + +LR++ R+ ++P Y L E
Sbjct: 379 LSDKAGDSLGRTSGGGGSGSKDKEQLPTLRIKCRFQSTDILPINVYGNFLTYLKENYKRV 438
Query: 627 VKALADLCRTD-RQPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATA 685
+ L + ++ + +++ G ++ ++ R GD + FRG SLAT
Sbjct: 439 CETLEPVIGVKAKEDIGQALVLLMHAQGLAGAFLTDVVALDLLRVGDQRLTFRGNSLATK 498
Query: 686 VLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMD--SPDDACNNAEFLLMILDQ 743
++ F++ + +LQ +S I +LI S++ E++PTK S L +
Sbjct: 499 SMEAFLKLTGEQYLQDTLSAPINELIQSERDCEVDPTKTSGSSAGSLQRQQAALRGAVRG 558
Query: 744 ITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRA 803
IF S + P +R C R + + + ++S IFLR +CPA++ P
Sbjct: 559 AWQCIFESHKHFPAQLRN-CFATFRERLQQLGRQDMA-DNLISASIFLRFLCPAILSPSL 616
Query: 804 WTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQL 863
+ + P A R+L +VAK LQ LAN F KE +ME +N F+ + RM FL+ +
Sbjct: 617 FNITSELPSARATRNLTLVAKTLQTLANFTRFQGKENFMEFLNDFLEQEAARMQQFLEII 676
Query: 864 SNVPDPGNSPPNSNVNF----EIAKELATLHHICVAHLTEL 900
S P+ + P+S +++ + K+L+ LH + L +L
Sbjct: 677 STRPE--HPAPDSILDWAGYIDQGKQLSILHSLLSESLAKL 715
>UniRef50_A4RH06 Cluster: Putative uncharacterized protein; n=2;
Sordariomycetes|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 1376
Score = 120 bits (289), Expect = 2e-25
Identities = 80/249 (32%), Positives = 129/249 (51%), Gaps = 4/249 (1%)
Query: 671 GDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDA 730
G+ LFRG SL T L+ MR FL + E I ++ + E++P K+ S +D
Sbjct: 885 GEANLLFRGNSLLTQALEFHMRRLGNEFLIEVLREKIFEINEINANCEVDPGKLQSGEDL 944
Query: 731 CNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNE-RFVRTRVVSGFI 789
+ L+ +I I TS P +R + ++ A ++ + R V VSGF+
Sbjct: 945 QTHWRQLIQYTTEIWECIATSTSKFPSELRQILKYVRAVAEDRYGDFLRTVSYTSVSGFL 1004
Query: 790 FLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFI 849
FLR ICPA++ P+ L++ P P AQR+L ++AK LQ +ANL G KE ++E +N FI
Sbjct: 1005 FLRFICPAILNPKLNGLLRDLPRPRAQRTLTLIAKGLQAMANLSTIGRKETWLEPMNKFI 1064
Query: 850 LKNKERMVVFLDQLSNVPDPGNS---PPNSNVNFEIAKELATLHHICVAHLTELQGLAKN 906
+++ + F+D + +VP ++ PP+ + IA L T + L L +++N
Sbjct: 1065 ASHRQSVKDFIDAICSVPAERSNPILPPSYSTPNTIASRLPTTGREGLPSLPYLIDMSRN 1124
Query: 907 QPAIRKLVT 915
A+ KL T
Sbjct: 1125 FAALIKLWT 1133
Score = 42.7 bits (96), Expect = 0.044
Identities = 35/125 (28%), Positives = 55/125 (44%), Gaps = 3/125 (2%)
Query: 554 KRGKESEV--AELTIELANLANGEEIEEWYPLVGMTPIGEWGSLRLRIRYMQELVMPREE 611
K G EV + I L NLA+G++ EEW+ + GSL ++R+ + V+ E
Sbjct: 728 KTGNILEVMCGSVDIPLTNLASGKDHEEWFQIYDSQQ-QSIGSLFAKVRHEELAVLRARE 786
Query: 612 YNPLRQLLLEPGIPAVKALADLCRTDRQPLATSVLNTFAECGRGAELARELTCAEVAREG 671
YNPL LL ++ + + LA LN F G +E L E+ G
Sbjct: 787 YNPLSDLLHNFSSGLTVQISSALPGNLRRLAEIFLNIFQVSGTTSEWLMTLVEDEIDGIG 846
Query: 672 DHKTL 676
+ ++
Sbjct: 847 NQGSM 851
>UniRef50_Q2GTK6 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 1119
Score = 119 bits (286), Expect = 4e-25
Identities = 66/199 (33%), Positives = 111/199 (55%), Gaps = 1/199 (0%)
Query: 670 EGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDD 729
+G+ LFRG SL T L+ MR K +L +++ IQ++ +S + E++P+K+ +D
Sbjct: 614 QGEANLLFRGNSLLTQALEFHMRRLGKEYLIDTLADRIQEINESDYSCEVDPSKVPHGED 673
Query: 730 ACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNE-RFVRTRVVSGF 788
+ L+ I I +S P +R++ ++ A ++ + R V VSGF
Sbjct: 674 VQQHWNHLIQFTTDIWDCIVSSAARLPPELRHILKYIRAVAEDRYGDFLRTVTYTSVSGF 733
Query: 789 IFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPF 848
+FLR +CPA++ P+ + L++ P P AQR+L ++AK LQ LANL G KE +ME +N F
Sbjct: 734 LFLRFLCPAILNPKLFGLLRDHPQPRAQRTLTLIAKSLQALANLSSIGKKETWMEPMNRF 793
Query: 849 ILKNKERMVVFLDQLSNVP 867
+ ++ FLD + +P
Sbjct: 794 LPSQRQSFKDFLDDVCAIP 812
>UniRef50_Q52KF5 Cluster: Dab2ip protein; n=13; Euteleostomi|Rep:
Dab2ip protein - Mus musculus (Mouse)
Length = 712
Score = 118 bits (284), Expect = 7e-25
Identities = 72/260 (27%), Positives = 139/260 (53%), Gaps = 5/260 (1%)
Query: 642 ATSVLNTFAECGRGAELARELTCAEVAREGDHKTL-FRGASLATAVLDEFMRAHCKPFLQ 700
A+++++ G+ + +L +EV R GD++ L FR +LAT ++E+++ + +LQ
Sbjct: 1 ASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQ 60
Query: 701 AAISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVR 760
A+ E I+ L +S + E++P+K S D + L M + I S P+ ++
Sbjct: 61 DALGEFIKALYESDENCEVDPSKCSSADLPEHQGN-LKMCCELAFCKIINSYCVFPRELK 119
Query: 761 YLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLL 820
+ ++ ++ + + R++S +FLR +CPA++ P + L+Q P R+L
Sbjct: 120 EVFASWRQECSSRGRPD--ISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTARTLT 177
Query: 821 MVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNF 880
++AK QNLAN +FG+KE YM +N F+ M FL ++SN P+ ++
Sbjct: 178 LIAKVTQNLANFAKFGSKEEYMSFMNQFLEHEWTNMQRFLLEISN-PETLSNTAGFEGYI 236
Query: 881 EIAKELATLHHICVAHLTEL 900
++ +EL++LH + +++L
Sbjct: 237 DLGRELSSLHSLLWEAVSQL 256
>UniRef50_P48423 Cluster: GTPase-activating protein; n=4;
Sophophora|Rep: GTPase-activating protein - Drosophila
melanogaster (Fruit fly)
Length = 1163
Score = 117 bits (281), Expect = 2e-24
Identities = 73/247 (29%), Positives = 124/247 (50%), Gaps = 7/247 (2%)
Query: 593 GSLRLRIRYMQELVMPREEYNPLRQLLLEP------GIPAVKALADLCRTDRQPLATSVL 646
GSLRL + Y + V P Y+ L LLLE + AV L +L + + +A ++
Sbjct: 455 GSLRLNLNYTADHVFPLATYDDLMNLLLESVDQRPITVSAVSILGELV-SGKTEVAQPLV 513
Query: 647 NTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISET 706
F R A + + L E++ D T+FRG +L + ++DE MR +L +
Sbjct: 514 RLFTHTERIAPIIKALADHEISHLTDPTTIFRGNTLVSKMMDEAMRLSGLHYLHQTLRPV 573
Query: 707 IQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCL 766
+ +++ K+ E++P+K+ N L ++++ +I S + CPK + + L
Sbjct: 574 LSQIVAEKKPCEIDPSKIKDRSAVDTNLHNLQDYVERVFEAITKSADRCPKVLCQIFHDL 633
Query: 767 QRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCL 826
+ A +P+ R VR VVSGFIFLR PA++ P+ + L R+L +++K +
Sbjct: 634 RECAGEHFPSNREVRYSVVSGFIFLRFFAPAILGPKLFDLTTERLDAQTSRTLTLISKTI 693
Query: 827 QNLANLV 833
Q+L NLV
Sbjct: 694 QSLGNLV 700
>UniRef50_A7EI47 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 756
Score = 116 bits (279), Expect = 3e-24
Identities = 68/198 (34%), Positives = 109/198 (55%), Gaps = 2/198 (1%)
Query: 676 LFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACNNAE 735
LFRG SL T LD MR K +L + + I+ + + E++P+++D+ + N E
Sbjct: 232 LFRGNSLLTQALDFHMRRVGKEYLSEILGDQIRTINNINPDCEVDPSRIDNDNAFDKNWE 291
Query: 736 FLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNE-RFVRTRVVSGFIFLRLI 794
L+ + + SI S CP +R + ++ A ++ + R V VSGFIFLR
Sbjct: 292 SLIALTTDVWRSIADSATRCPPELRQIFKYIRAVAEDRYGDFLRTVAYTSVSGFIFLRFF 351
Query: 795 CPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKE 854
CPA++ P+ + L+ P AQR+ ++AK LQ LANL FG KE +ME +N F+ ++++
Sbjct: 352 CPAILNPKLFGLLPDHPQQKAQRTFTLIAKSLQALANLSSFGQKESWMEPMNKFLYQHRQ 411
Query: 855 RMVVFLDQLSNV-PDPGN 871
+ FLD + + PD N
Sbjct: 412 GVKDFLDAICAIAPDRTN 429
Score = 41.5 bits (93), Expect = 0.10
Identities = 22/104 (21%), Positives = 52/104 (50%), Gaps = 1/104 (0%)
Query: 564 LTIELANLANGEEIEEWYPLVGMTPIGEWGSLRLRIRYMQELVMPREEYNPLRQLLLEPG 623
+ I + L G++ E W+P++ + G + +++R+ + +V+ ++Y P+ QLL
Sbjct: 82 IEIPVDKLERGKDNEAWWPILDQNQ-EQVGEMLMKVRHDEVVVLLAKDYQPISQLLHNFN 140
Query: 624 IPAVKALADLCRTDRQPLATSVLNTFAECGRGAELARELTCAEV 667
++ + + + L+ ++N F G G+E + L E+
Sbjct: 141 SGLTLQISQVIPNNLRQLSEILINIFQVSGNGSEWLKALVEDEI 184
>UniRef50_A6SKM1 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 1943
Score = 115 bits (277), Expect = 5e-24
Identities = 74/231 (32%), Positives = 119/231 (51%), Gaps = 8/231 (3%)
Query: 668 AREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLI-DSKQT-AELNPTKMD 725
+RE + + L R +AT +L + + +L+A + + +++L+ SK EL+P +
Sbjct: 611 SRENEAELLRRNC-VATKLLSVYAKWKGAAYLKATLQKVLERLVLTSKDLDLELDPARTT 669
Query: 726 SPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVV 785
SP++ NA L ++ I S P R +C + + ++P+ +F V
Sbjct: 670 SPEELQKNALQLRVVTKVFIDDICNSASRIPVSFRKICNIISSCVMRRFPDAKFT---AV 726
Query: 786 SGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVV 845
FIFLR CPA+V P A L+ P +R LL++AK +QNLAN V FGAKEPYM +
Sbjct: 727 GAFIFLRFFCPAIVAPDAEGLIASPPSKEMRRGLLLIAKVVQNLANNVLFGAKEPYMYPL 786
Query: 846 NPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHICVAH 896
N F+ +N R+ FL ++S P+ + S +F+ +A LH H
Sbjct: 787 NDFLTQNIYRVTTFLREISAPPNVRETLAESE-SFDFGSCVA-LHRFLYDH 835
>UniRef50_A7F7G1 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 2561
Score = 114 bits (275), Expect = 9e-24
Identities = 72/223 (32%), Positives = 114/223 (51%), Gaps = 7/223 (3%)
Query: 676 LFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLI-DSKQT-AELNPTKMDSPDDACNN 733
L R +AT +L + + +L+A + + +++L+ SK EL+P + SP++ N
Sbjct: 1264 LLRRNCVATKLLSVYAKWKGAAYLKATLQKVLERLVLTSKDLDLELDPARTTSPEELQKN 1323
Query: 734 AEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRL 793
A L ++ I S P R +C + + ++P+ +F V FIFLR
Sbjct: 1324 ALQLRVVTKVFIDDICNSASRIPVSFRKICNIISSCVMRRFPDAKFT---AVGAFIFLRF 1380
Query: 794 ICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNK 853
CPA+V P A L+ P +R LL++AK +QNLAN V FGAKEPYM +N F+ +N
Sbjct: 1381 FCPAIVAPDAEGLIASPPSKEMRRGLLLIAKVVQNLANNVLFGAKEPYMYPLNDFLTQNI 1440
Query: 854 ERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHICVAH 896
R+ FL ++S P+ + S +F+ +A LH H
Sbjct: 1441 YRVTTFLREISAPPNVRETLAESE-SFDFGSCVA-LHRFLYDH 1481
>UniRef50_Q0URT8 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 1428
Score = 113 bits (272), Expect = 2e-23
Identities = 60/192 (31%), Positives = 108/192 (56%), Gaps = 1/192 (0%)
Query: 676 LFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACNNAE 735
LFRG +L T LD M+ K +L+ +SE ++++ + E++P K+ S + N
Sbjct: 811 LFRGNTLLTKSLDLHMKRLGKEYLEETLSEKLKEINEKDPECEVDPNKVTSQHELDRNWR 870
Query: 736 FLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNE-RFVRTRVVSGFIFLRLI 794
L+ +++ +I+ S CP+ +R + ++ A ++ + R V VSGF+FLR
Sbjct: 871 RLINCTEEVWRAIYNSISRCPQELRLIFRHIRACAEDRYGDYLRTVAYSSVSGFLFLRFF 930
Query: 795 CPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKE 854
PA++ P+ + L++ P P A+R+ ++AK LQ LAN+ FG KE +ME +N F+ ++
Sbjct: 931 VPAVLNPKLFGLLKDHPKPRARRTFTLIAKSLQGLANMSSFGTKEAWMEPMNTFLTSHRL 990
Query: 855 RMVVFLDQLSNV 866
+LD + +V
Sbjct: 991 EFKKYLDDICSV 1002
Score = 39.9 bits (89), Expect = 0.31
Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 5/115 (4%)
Query: 558 ESEVAELTIELANLANGEEIEEWYPLVGMTPIGEWGSLRLRIRYMQELVMPREEYNPLRQ 617
+ V + I L +L +E E+W+PLV M G + +++ + ++ +Y PL +
Sbjct: 648 DQTVGKTDIYLDDLGPNQETEKWWPLVNMYG-NSVGEVLVKVSSEECAILMARDYYPLSE 706
Query: 618 LLLEPGIPAVKALADLCRTDRQPLATSVLNTFAECGRGAELARELTCAEVAREGD 672
LL +A + D + L+ +LN F G A E CA V E D
Sbjct: 707 LLHRFSNSLTLQIAQMNTNDLKKLSEYLLNIFQVSG----AAGEWLCALVEEEID 757
>UniRef50_Q4SHY4 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 5 SCAF14581, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 717
Score = 112 bits (269), Expect = 5e-23
Identities = 91/340 (26%), Positives = 150/340 (44%), Gaps = 14/340 (4%)
Query: 556 GKESEVAELTIELANLANGEEIEEWYPLVGMTPIGEW--GSLRLRIRYMQELVMPREEYN 613
GK +V EL N+ E+ +P TP+ + S + +R PRE +
Sbjct: 76 GKSVKVEELGSLRLNIVYTED--HVFPSEHYTPLRDLLLHSADVGVRADSATGGPRESFA 133
Query: 614 PLRQLLLEP-GIPAVKALADLCRTDRQPLATSVLNTFAECGRGAELARELTCAEVAREGD 672
P L +P L ++CR ++Q A ++ F G+ + AE+ R D
Sbjct: 134 PCLLLSRQPVSASTAHILGEVCR-EKQEAAIPLVRLFLHYGKIVPFISAIAHAEINRTQD 192
Query: 673 HKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACN 732
T+FRG SL + +DE M+ +LQ + I ++ + E++P K+ ++
Sbjct: 193 PNTIFRGNSLTSKCIDETMKLAGMHYLQVTLKPIIDEICTEHKPCEIDPVKLKESENLET 252
Query: 733 NAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLR 792
N E L +D I I TS CP + + L+ +A ++ + VR VS FIFLR
Sbjct: 253 NRENLRHYVDHIFRVITTSGVRCPTVMCDIFFSLRESAAIRFQVDPDVRFTAVSSFIFLR 312
Query: 793 LICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGA---KEPYMEVVNPFI 849
PA++ P + L P P R+L +++K +Q L +L + + KE YM +
Sbjct: 313 FFAPAILSPNLFHLRPHHPDPATSRTLTLISKTIQTLGSLAKSRSANFKESYMAAFYDYF 372
Query: 850 LKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATL 889
+ K + D + NV G+S F I ++TL
Sbjct: 373 NEKK-----YADAVKNVSVSGSSRWGFMSWFHICASISTL 407
>UniRef50_Q7RW81 Cluster: Putative uncharacterized protein NCU03852.1;
n=1; Neurospora crassa|Rep: Putative uncharacterized
protein NCU03852.1 - Neurospora crassa
Length = 1405
Score = 111 bits (266), Expect = 1e-22
Identities = 75/251 (29%), Positives = 126/251 (50%), Gaps = 10/251 (3%)
Query: 671 GDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDA 730
G+ LFRG SL T + +MR K +L+ ++ I+++ + E++P++M + DD
Sbjct: 929 GEASLLFRGNSLLTQAFEIYMRRLGKEYLEETLAAKIREINELDLDCEVDPSRMQNGDDI 988
Query: 731 CNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRV-----V 785
+ L+ + + I +S P +R++ ++ AVA+ F+RT V
Sbjct: 989 QQHWAKLIELTSAVWRCIASSAHRLPSEIRHVLKYIR--AVAEDRYGHFIRTATAVYTSV 1046
Query: 786 SGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVV 845
SGF+FLR +CPA++ P+ + L++ P P AQR+L ++AK +Q LANL KE +ME +
Sbjct: 1047 SGFLFLRFLCPAILNPKLFGLLRDHPKPRAQRTLTLIAKTIQALANLNISSKKETWMEPM 1106
Query: 846 NPFILKNKERMVVFLDQLSNVPDPGNS---PPNSNVNFEIAKELATLHHICVAHLTELQG 902
F+ K ++ F D + +P S P + I L+ L L L
Sbjct: 1107 TEFLQKQRQPFKDFADAVCAIPAESTSNSVPAPYSTPLTILGRLSPLAREGFPSLPYLVD 1166
Query: 903 LAKNQPAIRKL 913
A+N A+ KL
Sbjct: 1167 HARNFAALAKL 1177
Score = 39.5 bits (88), Expect = 0.41
Identities = 28/112 (25%), Positives = 52/112 (46%), Gaps = 2/112 (1%)
Query: 546 TITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPIGEWGSLRLRIRYMQEL 605
T+ + TG+ E+ + I L L G++ E+W + G++ L++ + + +
Sbjct: 767 TLGLPKTGQLS-EALCGAVDIPLHLLERGKDHEQWLQVYDARQ-QSIGTMLLKVHHEEVV 824
Query: 606 VMPREEYNPLRQLLLEPGIPAVKALADLCRTDRQPLATSVLNTFAECGRGAE 657
V+ EY PL +LL G +AD+ + + LA +N F G+ E
Sbjct: 825 VLQSREYQPLSELLHRFGSGLTTQIADVMPGNLRKLAEIFVNIFQVSGKATE 876
>UniRef50_Q8SSU4 Cluster: Similar to Dictyostelium discoideum (Slime
mold). Nucleotide exchange factor RasGEF P; n=2;
Dictyostelium discoideum|Rep: Similar to Dictyostelium
discoideum (Slime mold). Nucleotide exchange factor
RasGEF P - Dictyostelium discoideum (Slime mold)
Length = 1728
Score = 110 bits (264), Expect = 2e-22
Identities = 78/268 (29%), Positives = 129/268 (48%), Gaps = 7/268 (2%)
Query: 602 MQELVMPREEYNPLRQLLLEPGIPAVKALAD-LCRTDRQPLATSVLNTFAECGRGAELAR 660
M L + + L L++ + V ++ D + T Q LA S+++ F + L +
Sbjct: 529 MHNLARIKSYHKELLDLIVTSKLGLVHSICDSIDITAAQMLAKSLVDVFHTHHKLLHLLK 588
Query: 661 ELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELN 720
EV++ D TLFR S+A ++ + + +LQ ++ + L +S + E++
Sbjct: 589 SFIKKEVSQCHDPGTLFRSNSVAMKMVVAYGLKSAQHYLQQTLTPLVVDLCNSPLSLEVD 648
Query: 721 PTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFV 780
P K+ +D N + L ++ + I S E CPK + +C ++ K+P
Sbjct: 649 PIKLSPGEDIEMNIKNLKIVSQKFFDRIINSIEQCPKSIIEICYYFKKIVSRKFPTH--- 705
Query: 781 RTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQ-RSLLMVAKCLQNLANLVEFGAKE 839
V GFIFLRL CPA V P ++ + RSL++VAKCLQNL+N V F +
Sbjct: 706 WKSAVGGFIFLRLFCPACVSPEGQAIISPGRVGITERRSLILVAKCLQNLSNQVLF--NQ 763
Query: 840 PYMEVVNPFILKNKERMVVFLDQLSNVP 867
PYME +N FI N + F + ++ P
Sbjct: 764 PYMETINDFIHNNLPALDDFFMKCASRP 791
>UniRef50_Q6C802 Cluster: Yarrowia lipolytica chromosome D of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome D of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 1139
Score = 110 bits (264), Expect = 2e-22
Identities = 77/314 (24%), Positives = 154/314 (49%), Gaps = 21/314 (6%)
Query: 571 LANGEEIEEWYPLVGMTPIGEWGSLRLRIRYMQELVMPREEYNPLRQLLLEPG--IPAVK 628
L G +E+W + + G + ++I Y V+ +Y L +L + + A
Sbjct: 552 LVQGPAVEQWVKIYDVNDGSTLGDVCIKISYFGSNVLAPHQYEHLEAMLKDTDSRLSAKI 611
Query: 629 ALADLCRTDRQPLATSVLNTFAEC---------GRGAELARELTCAEVAREGDHKTLFRG 679
+ A + + + + + C G +LA ++T + +++ + LFRG
Sbjct: 612 SEARMSLPEYTDMFVKIYSCLGICDQWLMSLIDGEIGKLADKVTANDRSKQVSN-LLFRG 670
Query: 680 ASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMD-----SPDDA---C 731
+L T ++++M+ +L+ + + +++++D + EL+P+++D +P+
Sbjct: 671 NTLMTKAIEKYMQLTAHSYLRDLVGKVVRQVLDRDEKLELDPSRLDDGHGITPEIEQLKV 730
Query: 732 NNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFL 791
+N E L+ + I ++I + P+ + + L++ +E V + SGF+FL
Sbjct: 731 HNQERLMAHAETIWVNIRNTIADIPQSLVVVFQYLRQQLEGLHQDEEVVFNGI-SGFLFL 789
Query: 792 RLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILK 851
R ICPAL+ P+ + LV +P P QR+L ++AK +Q+ AN F AKE +M + PFI
Sbjct: 790 RFICPALLSPKLFGLVHNSPQPEVQRTLTLLAKLMQSFANRANFTAKESFMIPLTPFIEN 849
Query: 852 NKERMVVFLDQLSN 865
NK+ + + +SN
Sbjct: 850 NKKELCQYFRVISN 863
>UniRef50_A2CE77 Cluster: Novel protein similar to vertebrate RAS
p21 protein activator 4; n=9; Euteleostomi|Rep: Novel
protein similar to vertebrate RAS p21 protein activator
4 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 800
Score = 106 bits (255), Expect = 2e-21
Identities = 79/297 (26%), Positives = 140/297 (47%), Gaps = 21/297 (7%)
Query: 590 GEWGSLRLRIRYMQELVMPREEYNPLRQLLLEPGI-PAVKALADLCRT--DRQPLATSVL 646
G GSLRL +R E+V+P Y PL +LL + G P L D T RQ +A +++
Sbjct: 248 GTLGSLRLHLRLRDEVVLPSSHYKPLTELLSQSGNWPDFIMLIDETTTAESRQEVANNLV 307
Query: 647 NTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISET 706
F G E L E+ + + TLFR SLA+ ++ F++ +L +
Sbjct: 308 KLFLGQGLVKEFLDVLFKLELDKTTEPNTLFRSNSLASKSMESFLKVAGMQYLHRLLGPI 367
Query: 707 IQKLIDSKQTAELNPTKMDSPDDAC--------------NNAEFLLMILDQITLSIFTSP 752
I ++ + K+ EL+P+K++ + C ++ L L ++ SI S
Sbjct: 368 INRIFEEKKYVELDPSKVELKEAGCAGLHRQQTESDVIQQSSSLLQSYLSELLTSILQSA 427
Query: 753 EACPKPVRYLCGCLQRAAVAKWPNERF--VRTRVVSGFIFLRLICPALVEPRAWTLVQRA 810
CP + + L ++P+ + V+ V+ F+ LR I PA++ P+ + L ++
Sbjct: 428 SYCPLLICQVFHQLYLRVQERFPDPEYRKVKFIAVTSFLCLRFISPAIMSPKLFHLREKH 487
Query: 811 PPPHAQRSLLMVAKCLQNLANLVEFG--AKEPYMEVVNPFILKNKERMVVFLDQLSN 865
R+LL++AK +Q + N+ +KEP+M + P I + ++ F+ +L N
Sbjct: 488 ADARTSRTLLLLAKAVQTIGNMDTLACCSKEPWMVRLQPAIQQGITQLKDFITRLVN 544
>UniRef50_O43374 Cluster: Ras GTPase-activating protein 4; n=65;
Eumetazoa|Rep: Ras GTPase-activating protein 4 - Homo
sapiens (Human)
Length = 803
Score = 105 bits (253), Expect = 4e-21
Identities = 83/306 (27%), Positives = 144/306 (47%), Gaps = 28/306 (9%)
Query: 590 GEWGSLRLRIRYMQELVMPREEYNPLRQLLLE--------PGIPAVKALADLCRTD-RQP 640
G GSL+L +R E V+P Y PL LL PG + + + T+ RQ
Sbjct: 247 GNLGSLQLEVRLRDETVLPSSYYQPLVHLLCHEVKLGMQGPG-QLIPLIEETTSTECRQD 305
Query: 641 LATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQ 700
+AT++L F G + L E++R + TLFR SLA+ ++ F++ +L
Sbjct: 306 VATNLLKLFLGQGLAKDFLDLLFQLELSRTSETNTLFRSNSLASKSMESFLKVAGMQYLH 365
Query: 701 AAISETIQKLIDSKQTAELNPTKMDSPDDACN--------------NAEFLLMILDQITL 746
+ I K+ + K+ EL+P+K++ D C+ +A+ L L +
Sbjct: 366 GVLGPIINKVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLS 425
Query: 747 SIFTSPEACPKPVRYLCGCLQRAAVAKWPNERF--VRTRVVSGFIFLRLICPALVEPRAW 804
++ S ACP VR L R ++P + V V+ F+ LR PA++ P+ +
Sbjct: 426 ALSRSVRACPAVVRATFRQLFRRVRERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPKLF 485
Query: 805 TLVQRAPPPHAQRSLLMVAKCLQNLANL--VEFGAKEPYMEVVNPFILKNKERMVVFLDQ 862
L +R R+LL++AK +QN+ N+ AKE +ME + P + + ++ F+ +
Sbjct: 486 HLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVRQGVAQLKDFITK 545
Query: 863 LSNVPD 868
L ++ +
Sbjct: 546 LVDIEE 551
>UniRef50_Q7PTK8 Cluster: ENSANGP00000021695; n=2; Culicidae|Rep:
ENSANGP00000021695 - Anopheles gambiae str. PEST
Length = 929
Score = 103 bits (248), Expect = 2e-20
Identities = 76/293 (25%), Positives = 141/293 (48%), Gaps = 14/293 (4%)
Query: 593 GSLRLRIRYMQELVMPREEYNPLRQLLLEP------GIPAVKALADLCRTDRQPLATSVL 646
GSLRL++ Y + V P Y+ L +L++ AV L ++ ++ +A ++
Sbjct: 389 GSLRLKLNYTSDHVFPLATYDQLYNVLIQSIEQKPITASAVHILGEISH-NKTEVAQPLV 447
Query: 647 NTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISET 706
F A + + L E+++ D T+FRG +L + ++DE MR +L A +
Sbjct: 448 RLFTHTNVIAPMIKALADHEISKLTDPTTIFRGNTLVSKMMDEAMRLSGLHYLHATLRPI 507
Query: 707 IQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCL 766
++++ ++ E++P+++ N L + ++ +I S CP + + L
Sbjct: 508 VEQIFAERKPCEIDPSRVKDVGAIEGNLHNLQDYVGKVFEAITQSAVKCPAILCEIFHNL 567
Query: 767 QRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCL 826
+ A +P + VR VVSGFIFLR PA++ P+ + L R+L +++K +
Sbjct: 568 RECAAKYFPQNKEVRYSVVSGFIFLRFFAPAILGPKLFDLTTEPGDDQINRTLTLISKTI 627
Query: 827 QNLANLV-----EFGAKEPYME-VVNPFIL-KNKERMVVFLDQLSNVPDPGNS 872
Q++ NLV + KE Y E + F ++ E + FL+ +S V G+S
Sbjct: 628 QSMGNLVSSRSAQHPCKEKYTEQLYKKFCTEQHVEAIKHFLEVISTVGATGDS 680
>UniRef50_Q6CW67 Cluster: Kluyveromyces lactis strain NRRL Y-1140
chromosome B of strain NRRL Y- 1140 of Kluyveromyces
lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
lactis strain NRRL Y-1140 chromosome B of strain NRRL Y-
1140 of Kluyveromyces lactis - Kluyveromyces lactis
(Yeast) (Candida sphaerica)
Length = 1046
Score = 103 bits (248), Expect = 2e-20
Identities = 55/201 (27%), Positives = 111/201 (55%), Gaps = 9/201 (4%)
Query: 673 HKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACN 732
+ TLFRG S+ T ++ + + +L I I++L++ ++ E++P ++ +
Sbjct: 576 YNTLFRGNSILTKTMETYCYRVGQEYLDKCIGTVIRQLVEEDESYEIDPNRIKESELTEK 635
Query: 733 ------NAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRV-- 784
N + LL + ++ IF + P+ ++ C ++ P+E+ +
Sbjct: 636 EKIIETNFQKLLSLAERTWKLIFETSNDLPQGIKTQLKCFRKKLEIIEPDEKISSKSLLN 695
Query: 785 -VSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYME 843
+SGF+FLR CP ++ P+ + V+ P +A+RSL ++AK + NL+ L EFG+KEP+M+
Sbjct: 696 CISGFLFLRFFCPVILNPKIFNFVEHHPGENARRSLTLLAKVVMNLSTLTEFGSKEPWMK 755
Query: 844 VVNPFILKNKERMVVFLDQLS 864
+N FI +K +++ +LD+++
Sbjct: 756 RMNSFIDDHKGQLLDYLDKIT 776
>UniRef50_Q54T13 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 464
Score = 101 bits (241), Expect = 1e-19
Identities = 84/354 (23%), Positives = 156/354 (44%), Gaps = 17/354 (4%)
Query: 526 DPHWXXXXXXXXMPPDVTSLTITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLVG 585
+P W + + ++I +++ K K+ + + I + + + W PL G
Sbjct: 50 NPVWKDEEFVFDVIENSQIISILMYDEDKFSKDDFMGLVRINIDEYKTKGQRDIWIPLEG 109
Query: 586 MTPIGEWGSLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRTDRQPLATSV 645
P + + + R + + + L L++ + L+ +D ++
Sbjct: 110 KNP-----NKKAKKRGDIHIQLCYYSFTSLTNYLIKNNHSLIIKLSKQLISD--DFGKAI 162
Query: 646 LNTFAECGR-GAEL---ARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQA 701
+ F+ C G EL R+L E+ + D K LFR SL+T V+ + +L+
Sbjct: 163 MYYFSNCSESGKELIDIVRDLASIEIEQTNDAKVLFRTDSLSTKVIVSIFKTIGFGYLKE 222
Query: 702 AISETIQKLIDSKQTAELNPTKMDSPD-DACNNAEFLLMILDQITLSIFTS-PEACPKPV 759
A+ I +I + E++P+K + + NA L +I S + P +
Sbjct: 223 ALCPLIMSMIKNDINLEVDPSKGGITEAEVEQNAIQLSFFCSSFITAIKASLADQLPIEI 282
Query: 760 RYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSL 819
R +C + + K+PN+ + V GF FLR + PA+ P A L+ AP + +R+L
Sbjct: 283 RQICQIINQLVEKKYPNDNI---KSVGGFFFLRFVNPAIFSPEALGLISVAPNSNVRRTL 339
Query: 820 LMVAKCLQNLANLVEFGA-KEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNS 872
+V+K LQN++N V F + KE Y+ N FI + + L ++S+ D N+
Sbjct: 340 TLVSKILQNISNQVTFSSGKEEYLSSFNNFISSRFDDFKIILQEVSSFNDNNNN 393
>UniRef50_Q5KFG6 Cluster: Ras GTPase activator, putative; n=2;
Filobasidiella neoformans|Rep: Ras GTPase activator,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 2665
Score = 100 bits (240), Expect = 2e-19
Identities = 76/267 (28%), Positives = 122/267 (45%), Gaps = 12/267 (4%)
Query: 605 LVMPREEYNPLRQL--LLEPGIPAVKALADLCR---TDRQPLATSVLNTFAECGRGAELA 659
L R Y P L L P + A+ D+C + L+T + F G L
Sbjct: 1263 LAAKRISYAPKLYLEGLTNPNLALALAMVDVCPQTGAEVDELSTLLFRVFEGKGTLLGLM 1322
Query: 660 RELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLID--SKQTA 717
R L EV LFR S+ ++ F + + ++A + I L + ++ +
Sbjct: 1323 RVLIEREVTMTNHESELFRANSITMRMITIFAKTYGYNHVRATLQPLILSLAEKPAECSF 1382
Query: 718 ELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNE 777
EL+P K DD N++ L ++ + I +S P R +C + ++P+
Sbjct: 1383 ELDPRKAAPGDDIERNSDHLRLMCQALLDLICSSTPRVPLMFRAVCHHIWEVVDDRFPDS 1442
Query: 778 RFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGA 837
R V FIFLR CPA+V P + L +R+LL++ K +QNLAN V F
Sbjct: 1443 RH---SAVGSFIFLRFFCPAIVSPESIDLDVNPDTRETRRALLLITKVIQNLANNVVF-- 1497
Query: 838 KEPYMEVVNPFILKNKERMVVFLDQLS 864
KEP+M+V+NPF+ N +++ FL ++
Sbjct: 1498 KEPHMKVLNPFLSDNIKQVTKFLSDIA 1524
>UniRef50_O01398 Cluster: Neurofibromin; n=12; cellular organisms|Rep:
Neurofibromin - Drosophila melanogaster (Fruit fly)
Length = 2802
Score = 100 bits (239), Expect = 2e-19
Identities = 73/276 (26%), Positives = 133/276 (48%), Gaps = 5/276 (1%)
Query: 624 IPAVKALADLCRTDRQPLATSVLNTFAECGRG-AELARELTCAEVAREGDHKTLFRGASL 682
+P ALA++ T + VL T + + L + EV +TLFRG SL
Sbjct: 1265 LPIAMALANVVTTSQMDELARVLVTLFDAKHLLSPLLWNMFYREVEVSDCMQTLFRGNSL 1324
Query: 683 ATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTA--ELNPTKMDSPDDACNNAEFLLMI 740
+ ++ + + +LQ + I+ L+D ++ E++P ++D +D + L+ +
Sbjct: 1325 GSKIMAFCFKIYGASYLQMLLEPLIRPLLDEEEETCFEVDPARLDPTEDIEQHRNNLIAL 1384
Query: 741 LDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVE 800
++ +I S + P +R +C CL + ++PN V IFLR I PA+V
Sbjct: 1385 TQKVFDAIINSSDRLPPQLRSMCHCLYQVLSKRFPNLLQNNIGAVGTVIFLRFINPAIVS 1444
Query: 801 PRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFL 860
P+ +V + A+R L++++K LQN+AN VEF +KE +M N F+ + E F
Sbjct: 1445 PQELGIVDKQVHSSAKRGLMLMSKILQNIANHVEF-SKEQHMLCFNDFLRDHFEAGRRFF 1503
Query: 861 DQLSNVPDPGNSPPNSNVNFEIAKELATLHHICVAH 896
Q+++ + + +S ++F + LH + H
Sbjct: 1504 IQIASDCETVDQTSHS-MSFISDANVLALHRLLWTH 1538
>UniRef50_UPI000049A55D Cluster: Ras GTPase activating protein; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: Ras GTPase
activating protein - Entamoeba histolytica HM-1:IMSS
Length = 769
Score = 99.5 bits (237), Expect = 4e-19
Identities = 61/201 (30%), Positives = 101/201 (50%), Gaps = 3/201 (1%)
Query: 645 VLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAIS 704
V+ F R + L E + LFR +L T +L + R K FL +
Sbjct: 79 VIQVFTMNDRILPFIKFLINREFEESRSREELFRQNTLCTRILTAYARITSKKFLSTTLK 138
Query: 705 ETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCG 764
++ K++++ Q+ E++ K+ +N L +I +I TS P +R +C
Sbjct: 139 NSVLKMVNTNQSFEIDELKILPGQILGSNLAALQSTCKEILENISTSRCDVPIEIRTICN 198
Query: 765 CLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTL--VQRAPPPHAQRSLLMV 822
CL + + N++ + +++V GF+FLRL CPA+ P + L V+ P A+R+L++V
Sbjct: 199 CLWENCLKYFKNDKELPSQIVGGFLFLRLFCPAIASPENFGLLGVESKVSPKARRNLILV 258
Query: 823 AKCLQNLANLVEFGAKEPYME 843
K LQN+AN V AKE Y+E
Sbjct: 259 TKVLQNIANQVT-TAKEKYLE 278
>UniRef50_UPI0000499EEB Cluster: Ras GTPase activating protein; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: Ras GTPase
activating protein - Entamoeba histolytica HM-1:IMSS
Length = 944
Score = 96.7 bits (230), Expect = 3e-18
Identities = 59/211 (27%), Positives = 102/211 (48%), Gaps = 5/211 (2%)
Query: 666 EVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMD 725
E + TLFR +L + ++ F ++ C+PFL+ + I ++ E++ K
Sbjct: 75 EFDKSNSEGTLFRSNNLCSRMMTHFAKSSCRPFLRTTLKNVINEINVCPHLLEIDTQKDP 134
Query: 726 S--PDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTR 783
S P N E L + SI ++ P + +C L R + K+P + +
Sbjct: 135 SLTPQLIAKNTELLQAYTTKFIRSIESNLHNLPVQIIEICKQLYRHSQNKFPQSKLLPFT 194
Query: 784 VVSGFIFLRLICPALVEPRAWTLVQRAP-PPHAQRSLLMVAKCLQNLANLVEFGAKEPYM 842
+V GF+FLR+ICP+L P A + P P+ +R+L+++ K +QN+AN V KEPY
Sbjct: 195 MVGGFLFLRVICPSLAAPEASGIEMTHPIQPNCRRNLILITKIIQNIANNVT-STKEPYF 253
Query: 843 EVVNPFILKNKERMVVFLDQLSNVPDPGNSP 873
+ PF ++ ++ ++ L NSP
Sbjct: 254 KQTIPFTIEMSAKLNNDIEMLC-TKTSSNSP 283
>UniRef50_UPI000066100B Cluster: Ras GTPase-activating protein nGAP
(RAS protein activator-like 1).; n=2; Euteleostomi|Rep:
Ras GTPase-activating protein nGAP (RAS protein
activator-like 1). - Takifugu rubripes
Length = 705
Score = 95.1 bits (226), Expect = 8e-18
Identities = 65/222 (29%), Positives = 113/222 (50%), Gaps = 14/222 (6%)
Query: 661 ELTCAEVAREGDHKTL-FRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAEL 719
+L +EV R DH L FR +LAT ++E+++ F++A L +S++ E+
Sbjct: 6 DLVMSEVDRCADHDVLIFRENTLATKAIEEYLKLVGXEFIKA--------LYESEENCEV 57
Query: 720 NPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYL-CGCLQRAAVAKWPNER 778
+P++ S + L M + I S P+ ++ + Q+ ++ P +
Sbjct: 58 DPSRC-SAAKLPEHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCSLGGHPPD- 115
Query: 779 FVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAK 838
+ R++S +FLR +CPA++ P + L+Q P R+L ++AK +QNLAN FG K
Sbjct: 116 -IGRRLISSSLFLRFLCPAIMSPSLFRLMQEYPDDRTSRTLTLIAKVIQNLANFTRFGTK 174
Query: 839 EPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNF 880
E YM +N F+ M+ FL ++S+ PD +S P +F
Sbjct: 175 EEYMTFMNDFLEHEWAGMLRFLTEISD-PDALSSSPGGENSF 215
>UniRef50_UPI000049A289 Cluster: Ras GTPase activating protein; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: Ras GTPase
activating protein - Entamoeba histolytica HM-1:IMSS
Length = 727
Score = 94.7 bits (225), Expect = 1e-17
Identities = 70/241 (29%), Positives = 114/241 (47%), Gaps = 17/241 (7%)
Query: 675 TLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDS-------- 726
TLFR SL T V + R C+ F+ IQK+I + EL+P K+ +
Sbjct: 95 TLFRTNSLCTKVQTAYARKECQNFMMEVFQPIIQKVI-AMPPLELDPIKLQTLYPNKTEE 153
Query: 727 --PDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRV 784
++A N+ + L + D++ ++ P P+ +C ++ + ++ + +
Sbjct: 154 QLTEEANNSLQKLEDLSDEVIATLRRHLRNTPTPLSVMCHQIRESCFLYHTDDPDIALSL 213
Query: 785 VSGFIFLRLICPALVEPRAWTLVQRA-PPPHAQRSLLMVAKCLQNLANLVEFGAKEPYME 843
+ GF+FLRL CPAL P L A PP A+R+L+++ K LQN+AN V KEP+M
Sbjct: 214 IGGFVFLRLFCPALAAPEGSNLCGTAIVPPTARRTLILLTKILQNIANNVR-ETKEPWMT 272
Query: 844 VVNPFILKNKERMVVFLDQLSNVPDPGNSP----PNSNVNFEIAKELATLHHICVAHLTE 899
P+++ + +L LSN P S +N + EL L + V +LT
Sbjct: 273 NSLPYVMSRGPALQAYLKALSNAGIIKTKPTIIFEASQINPPLVIELHRLLNEAVPNLTT 332
Query: 900 L 900
L
Sbjct: 333 L 333
>UniRef50_UPI0000ECAA02 Cluster: RasGAP-activating-like protein 1.;
n=2; Gallus gallus|Rep: RasGAP-activating-like protein
1. - Gallus gallus
Length = 514
Score = 94.3 bits (224), Expect = 1e-17
Identities = 64/211 (30%), Positives = 110/211 (52%), Gaps = 16/211 (7%)
Query: 672 DHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMD------ 725
D TLFR SLA+ +++F++A P+L A + + ++ + K+ EL+P KM+
Sbjct: 241 DPNTLFRSNSLASKSVEQFLKAVGLPYLHAVLKPVVNRIFEEKKYVELDPCKMELSRSRR 300
Query: 726 -----SPDDAC---NNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNE 777
S +A ++ E L L +I S + CP +R L+R ++P+
Sbjct: 301 ISFKGSLSEAQVRESSLELLQGYLGDTVDAIVGSVDKCPLLMRVAFKRLRRRVEERFPSP 360
Query: 778 RF--VRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEF 835
+ V+ +SGF+FLR PA++ P+ + L ++ P R+LL++AK LQ++ NL
Sbjct: 361 QHEEVQYFAISGFLFLRFFAPAVLTPKLFGLREQHAEPRTGRTLLLLAKALQSIGNLGLQ 420
Query: 836 GAKEPYMEVVNPFILKNKERMVVFLDQLSNV 866
KEP+M ++ +L + R+ FLD L V
Sbjct: 421 PGKEPWMAPLHTVLLPSITRVRAFLDSLIEV 451
>UniRef50_Q4PF31 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 3023
Score = 93.1 bits (221), Expect = 3e-17
Identities = 67/260 (25%), Positives = 121/260 (46%), Gaps = 8/260 (3%)
Query: 615 LRQLLLEPGIPAVKALADLCR-TDRQPLATSVLNTFAECGRGAELARELTCAEVAREGDH 673
L L+ + + A+ +C + +P++ +L+ F G + E+ R
Sbjct: 1577 LLDLVCQNNLQLALAICQVCPGREVEPMSVLLLSVFDAKGGLIRFLKAAVEEEIQRTATE 1636
Query: 674 KTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQ--TAELNPTKMDSPDDAC 731
+ +FR S T +L F R H +L++ ++ I + E++P++++ A
Sbjct: 1637 EMVFRSNSFCTTLLSTFARTHGYDYLRSIMAPLITDFARKPAGFSVEMDPSRVEPGGSAL 1696
Query: 732 NNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFL 791
N L I +I +S P +R LC ++ A++P R+ + V G +FL
Sbjct: 1697 KNQTALEEIAQAFIDAICSSAHRVPAVLRELCRHIRNVLDARFPASRY---QGVGGLMFL 1753
Query: 792 RLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGA-KEPYMEVVNPFIL 850
R I PA+V P + P +R L++++K L LA+ F + KEP+M +N F+
Sbjct: 1754 RFISPAVVSPHMIDINLTGPSRDLRRGLVLISKILITLASNNLFSSHKEPFMTGLNDFLK 1813
Query: 851 KNKERMVVFLDQLSNV-PDP 869
N ++ FLDQ+S+ DP
Sbjct: 1814 SNVWKVTAFLDQVSDARTDP 1833
>UniRef50_Q22720 Cluster: Ras GTPase-activating protein gap-1; n=2;
Caenorhabditis|Rep: Ras GTPase-activating protein gap-1
- Caenorhabditis elegans
Length = 629
Score = 91.9 bits (218), Expect = 7e-17
Identities = 72/291 (24%), Positives = 132/291 (45%), Gaps = 13/291 (4%)
Query: 590 GEWGSLRLRIRYMQELVMPREEYNPLRQLLLEPG------IPAVKALADLCRTDRQPLAT 643
G+ G +++ Y + ++ + Y PL LL G V + L + + P++
Sbjct: 114 GDIGDATVKVTYQIDHILRMQVYKPLLDLLFLAGDVQPLTASLVAVIEALPKVELGPVSR 173
Query: 644 SVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAI 703
S++ A+ R + L + + D TLFRG SL+ +L E + + K +L +
Sbjct: 174 SLVELMAQSDRIRPVLSSLYVNSILKCQDENTLFRGQSLSGKMLFEILTTYGKMYLITTL 233
Query: 704 SETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLC 763
+ K+ ++ E++P ++ N LL+ + + TS CP ++ L
Sbjct: 234 KPVVDKIYKERKNCEVDPARVAVGASLEKNRNNLLVYFQMLFERVTTSSTNCPHLIKQLL 293
Query: 764 GCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVA 823
L R V + V+ VS F+ +R A++ P+A+ + + P R+LL+++
Sbjct: 294 YDL-RNVVGTHSSRSGVQRLAVSSFVIMRFFAAAILNPKAFEIRKDQPDLRVSRTLLLLS 352
Query: 824 KCLQNLANL-VEFG---AKEPYMEVVNPFIL--KNKERMVVFLDQLSNVPD 868
K LQ L+N V G +KE ++ V + ++K M FLD +S V D
Sbjct: 353 KLLQRLSNCSVSEGPLSSKEIWLNGVFETVTSEQHKSVMASFLDNISLVGD 403
>UniRef50_A2R7H8 Cluster: Function: sar1 of S. pombe encodes a
product capable of regulating ras1 function; n=19;
Dikarya|Rep: Function: sar1 of S. pombe encodes a
product capable of regulating ras1 function -
Aspergillus niger
Length = 780
Score = 91.1 bits (216), Expect = 1e-16
Identities = 49/123 (39%), Positives = 77/123 (62%), Gaps = 4/123 (3%)
Query: 748 IFTSPEACPKPVRYLCGCLQRAAVAKWPN--ERFVRTRVVSGFIFLRLICPALVEPRAWT 805
I S E P +R++C ++ + K+P+ ++ + T ++ GF FLR I PA+V PR++
Sbjct: 318 IIESVEETPYGIRWICKQIRSLSRRKYPDAQDQTICT-LIGGFFFLRFINPAIVTPRSYM 376
Query: 806 LVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSN 865
L++ P +R+L ++AK LQNLAN + AKEPYM + PFI +NKER+ F+ L +
Sbjct: 377 LIESTPTEKPRRTLTLIAKMLQNLANKPSY-AKEPYMAKLQPFIQQNKERVNKFMLDLCD 435
Query: 866 VPD 868
V D
Sbjct: 436 VQD 438
>UniRef50_Q5C1M0 Cluster: SJCHGC08700 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC08700 protein - Schistosoma
japonicum (Blood fluke)
Length = 223
Score = 87.8 bits (208), Expect = 1e-15
Identities = 70/221 (31%), Positives = 104/221 (47%), Gaps = 14/221 (6%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGS------YVLSYLGRT-GINH 113
P ++YHG +DR +E+RL + SYL+R S GS YVLSYL H
Sbjct: 7 PSLEQYYHGYIDRAEAEKRLQSFGISNSYLLRLSRADHGSDTWEDIYVLSYLSSALACFH 66
Query: 114 FRITAVCGDYYIGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXND--KKRVVAI 171
FR+ + +GGR FDS+ + Y + D++ ERL + +R+ A+
Sbjct: 67 FRLIPRFNCFQLGGRFFDSIDGCLSRY-YTRDIMTGERLKHPIPPTSLPIEYHTQRLRAV 125
Query: 172 LPYTKMPDTDELTFQKGDIFF-VHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPN 230
+ D L D F ++ D WL T+ ++ G + + VE P I
Sbjct: 126 QDFEPENAYDRLGCAVDDRFLLIYEDPNSDWLLATSLKSRHSGYLPKSCVEKEYPEIIER 185
Query: 231 TVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSL 271
F FHP+ T ++L KAGP S+L+RP D+ PG Y+L
Sbjct: 186 LEF--FHPDPTPHPK-ELLKKAGPFSYLLRPCDSRPGLYTL 223
>UniRef50_Q0UYR2 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 536
Score = 87.8 bits (208), Expect = 1e-15
Identities = 49/134 (36%), Positives = 78/134 (58%), Gaps = 4/134 (2%)
Query: 737 LLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPN--ERFVRTRVVSGFIFLRLI 794
L+ I + +I E P +R++C ++ + K+P+ ++ + T ++ GF FLR I
Sbjct: 84 LMEIANNFLTTIIKGLEETPYGIRWICKQIRSLSRRKYPDAQDQTICT-LIGGFFFLRFI 142
Query: 795 CPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKE 854
PA+V PR++ L+ P + +R L +AK LQNLAN + AKEPYM + PF+ +NK+
Sbjct: 143 NPAIVTPRSYMLIDATPAENPKRVLTYIAKMLQNLANKPSY-AKEPYMAKLQPFVHQNKD 201
Query: 855 RMVVFLDQLSNVPD 868
R+ FL L V D
Sbjct: 202 RINKFLLDLCEVQD 215
>UniRef50_Q54I64 Cluster: RasGTPase-activating protein; n=1;
Dictyostelium discoideum AX4|Rep: RasGTPase-activating
protein - Dictyostelium discoideum AX4
Length = 817
Score = 87.0 bits (206), Expect = 2e-15
Identities = 51/132 (38%), Positives = 79/132 (59%), Gaps = 2/132 (1%)
Query: 737 LLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRT-RVVSGFIFLRLIC 795
L+ I DQ SI +S +A P +R++C ++ K+P +T ++ GF LR I
Sbjct: 297 LIEIGDQFLDSILSSVDAVPYGIRWICKQIRELVKQKFPQATRAQTCGLIGGFFLLRYIN 356
Query: 796 PALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEF-GAKEPYMEVVNPFILKNKE 854
PA+V P+A+ LV + +R+L AK LQNLAN + F G KE +ME +N F+ +NK+
Sbjct: 357 PAVVTPQAFMLVDAKLSNNTKRNLTFPAKMLQNLANNIMFGGVKEFFMEPLNVFLDRNKD 416
Query: 855 RMVVFLDQLSNV 866
R+ FL+ L++V
Sbjct: 417 RLNDFLESLTDV 428
>UniRef50_Q4T1K3 Cluster: Chromosome 16 SCAF10562, whole genome
shotgun sequence; n=4; Euteleostomi|Rep: Chromosome 16
SCAF10562, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1724
Score = 84.6 bits (200), Expect = 1e-14
Identities = 71/281 (25%), Positives = 134/281 (47%), Gaps = 27/281 (9%)
Query: 624 IPAVKALADLCRTDR-QPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASL 682
+P ALA++ + LA ++ F +L + EV +TLFRG SL
Sbjct: 1307 LPIAMALANVVPGSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSL 1366
Query: 683 ATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQ--TAELNPTKMDSPDDACNNAEFLLMI 740
A+ ++ + + +LQ + ++ +I + + E++PT+++ ++ N LL I
Sbjct: 1367 ASKIMTFCFKVYGAAYLQKLLEPLLRGVITTPDHISFEVDPTRLEQGENLEENQSNLLQI 1426
Query: 741 LDQITLSIFTSPEACPKPVRYLCGCLQRAA----------------VAKWPNERFVRTRV 784
++ +I S P +R +C CL +A +AK ++RF + +
Sbjct: 1427 TERFFQAIIGSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENMAKVVSQRFPQNSI 1486
Query: 785 --VSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYM 842
V +FLR + PA+V P ++++ P P +R L +++K LQ++AN V F KE +M
Sbjct: 1487 GAVGSAMFLRFVNPAIVSPYEAGILEKKPLPRIERGLKLMSKILQSIANHVLF-TKEEHM 1545
Query: 843 EVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIA 883
N F+ N + F +++ +SPP+ +VN ++
Sbjct: 1546 RPFNDFVKSNFDAARRFFLDIAS-----DSPPSDSVNHSLS 1581
>UniRef50_P21359 Cluster: Neurofibromin (Neurofibromatosis-related
protein NF-1) [Contains: Neurofibromin truncated]; n=58;
Deuterostomia|Rep: Neurofibromin
(Neurofibromatosis-related protein NF-1) [Contains:
Neurofibromin truncated] - Homo sapiens (Human)
Length = 2839
Score = 83.4 bits (197), Expect = 3e-14
Identities = 77/293 (26%), Positives = 134/293 (45%), Gaps = 27/293 (9%)
Query: 624 IPAVKALADLCRTDR-QPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASL 682
+P ALA++ + LA ++ F +L + EV +TLFRG SL
Sbjct: 1221 LPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSL 1280
Query: 683 ATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQ----TAELNPTKMDSPDDACNNAEFLL 738
A+ ++ + + +LQ + ++ +I S + E++PT+++ + N LL
Sbjct: 1281 ASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLEPSESLEENQRNLL 1340
Query: 739 MILDQITLSIFTSPEACPKPVRYLCGCLQRA--------AVAKWPNE--------RFVRT 782
+ ++ +I +S P +R +C CL +A A K E RF +
Sbjct: 1341 QMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQN 1400
Query: 783 RV--VSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEP 840
+ V +FLR I PA+V P ++ + PPP +R L +++K LQ++AN V F KE
Sbjct: 1401 SIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLF-TKEE 1459
Query: 841 YMEVVNPFILKNKE-RMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHI 892
+M N F+ N + FLD S+ P + N +++F + LH +
Sbjct: 1460 HMRPFNDFVKSNFDAARRFFLDIASDCPT--SDAVNHSLSFISDGNVLALHRL 1510
>UniRef50_Q75DK0 Cluster: ABR021Wp; n=1; Eremothecium gossypii|Rep:
ABR021Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 1084
Score = 83.0 bits (196), Expect = 3e-14
Identities = 61/248 (24%), Positives = 119/248 (47%), Gaps = 19/248 (7%)
Query: 673 HKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACN 732
+ +LFRG S+ + ++++ + +L +I I++++ + EL+P ++ PD+
Sbjct: 607 YNSLFRGNSILSKSIEKYFNRIGQEYLDKSIGGIIRRIVAEEDMCELDPARIKEPDEIKK 666
Query: 733 ------NAEFLLMILDQITLSIFTSPEACPKPVRY-LCGCLQRAAVAKWPNERFVRTRVV 785
N L+ +I I+ + P ++ L ++ + + +
Sbjct: 667 RVILETNQAKLISWAKEIWHIIYKTSNDLPDAIKVQLTHIRKKLEIVCGDSNLKTVLNCI 726
Query: 786 SGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLL--MVAKCLQNLANLVEFGAKEPYME 843
SGF+FLR CP L+ P+ + R Q+ L ++ K L NL+ L FG KEP+M
Sbjct: 727 SGFLFLRFFCPVLLNPKLFQHYVRKNHSDEQKRRLFTLLTKVLMNLSTLTMFGPKEPWMN 786
Query: 844 VVNPFILKNKERMVVFLDQLSNVP-DPGN---------SPPNSNVNFEIAKELATLHHIC 893
+N FI ++K+ +V ++D+++ D N + P ++N EI +ELAT ++
Sbjct: 787 NMNHFIQEHKDELVDYIDKVTQRKLDFNNKILKLSNTVARPKLDMNKEIMRELATNPYLI 846
Query: 894 VAHLTELQ 901
+L E +
Sbjct: 847 ERYLRETE 854
>UniRef50_P33314 Cluster: Inhibitory regulator protein BUD2/CLA2;
n=2; Saccharomyces cerevisiae|Rep: Inhibitory regulator
protein BUD2/CLA2 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 1104
Score = 82.6 bits (195), Expect = 4e-14
Identities = 47/197 (23%), Positives = 103/197 (52%), Gaps = 7/197 (3%)
Query: 675 TLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDA---- 730
+LFRG S+ T ++++ +L A+S ++++I+S ++ EL+P ++ D+
Sbjct: 558 SLFRGNSILTKSIEQYFFRVGNEYLSKALSAILKEIIESNKSCELDPARVKEKDEVKKRK 617
Query: 731 --CNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCL-QRAAVAKWPNERFVRTRVVSG 787
+N + L + +I ++ + P +R + Q+ + + + +SG
Sbjct: 618 IIADNYKRLYSWVTKIWKRLYATSNDLPIEIRNVLKIFRQKLEIICIDDTLQIILNGISG 677
Query: 788 FIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNP 847
+FLR CP ++ P+ + V + A+R+L +++K L NL+ L +F KEP++ +N
Sbjct: 678 LLFLRFFCPVILNPKLFKYVSQNLNETARRNLTLISKVLLNLSTLTQFANKEPWLMKMNN 737
Query: 848 FILKNKERMVVFLDQLS 864
FI K ++ ++D+++
Sbjct: 738 FIDKRHNDLLDYIDKMT 754
>UniRef50_UPI0000E460AA Cluster: PREDICTED: similar to GAP-related
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to GAP-related protein -
Strongylocentrotus purpuratus
Length = 2248
Score = 82.2 bits (194), Expect = 6e-14
Identities = 65/249 (26%), Positives = 118/249 (47%), Gaps = 13/249 (5%)
Query: 624 IPAVKALADLCRTDRQP-LATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASL 682
+P ALA++ + + LA + F +L + EV +TLFRG SL
Sbjct: 645 LPIAMALANVIASSQMDELARVYVTLFDAKHLLYQLLWNMFSKEVELADCMQTLFRGNSL 704
Query: 683 ATAVLDEFMRAHCKPFLQAAISETIQKLID---SKQTAELNPTKMDSPDDACNNAEF--- 736
A+ ++ + + + +L+ + +Q+++ S E++ +M++ ++ N E+
Sbjct: 705 ASKIMAACFKMYGQNYLKLLLHPLVQEMMTGPTSHVRYEVDTARMEAHEEE-NLPEYQAS 763
Query: 737 LLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICP 796
L+ + + +I S + P +R +C CL ++P V IFLR I P
Sbjct: 764 LMQLAKKFFKAIINSVDQFPPQLRSVCHCLNEVVAQRFPMNSL---GAVGSAIFLRFINP 820
Query: 797 ALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERM 856
A+V P +V P QR L +V+K +QN+AN V+F KE +M N F+ +N R
Sbjct: 821 AIVSPYEHGIVNMKPSLKVQRGLKLVSKIMQNVANQVQF--KEQHMMHFNKFLSENAGRA 878
Query: 857 VVFLDQLSN 865
+ F +++
Sbjct: 879 IRFFQDIAS 887
>UniRef50_A7TTA0 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 874
Score = 81.0 bits (191), Expect = 1e-13
Identities = 71/301 (23%), Positives = 144/301 (47%), Gaps = 29/301 (9%)
Query: 591 EWGSLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALA---DLCRTDR-QPLATSVL 646
E G+L ++I L++P + ++L E +P + +A +C R + ++ +L
Sbjct: 463 EVGTLCVKISSSMNLILPPVNFKKFEKILRELPLPKIADIAYSDTICSNLRLEDVSEILL 522
Query: 647 NTFAECGRGAE-----LARELT-----CAEVAREG---DH--KTLFRGASLATAVLDEFM 691
+ F R + L +EL +E G +H ++FR S+ T L+ +
Sbjct: 523 DFFQSYNREDDWFVTLLNKELLDLNKKSSESLENGSGSNHILNSIFRSNSILTKSLERYF 582
Query: 692 RAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDAC------NNAEFLLMILDQIT 745
+ +L AAI + +++++ S E++ +K++ D+ N L+ + +I
Sbjct: 583 YRIGEEYLNAAIGDILREIVISDDYCEIDASKININDNIKLTEILEENRLKLIGWVTKIW 642
Query: 746 LSIFTSPEACPKPVRYLCGCLQRAAVAKWP--NERFVRT--RVVSGFIFLRLICPALVEP 801
+I+T+ P ++ L++ +P NE R + VS +FLR CP ++ P
Sbjct: 643 NAIYTTNSDLPFLIKSQLKNLRKKLDLIYPDRNEEMDRIILKSVSSILFLRFFCPVILNP 702
Query: 802 RAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLD 861
+ + ++ P + +R+ ++ K L NL+ L F KEP+M +N FI ++E M+ ++D
Sbjct: 703 KLFNFIETLPNENTRRTFTLITKTLLNLSTLTRFETKEPWMRPMNEFIDAHREEMLDYVD 762
Query: 862 Q 862
+
Sbjct: 763 K 763
>UniRef50_Q6CMT2 Cluster: Kluyveromyces lactis strain NRRL Y-1140
chromosome E of strain NRRL Y- 1140 of Kluyveromyces
lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
lactis strain NRRL Y-1140 chromosome E of strain NRRL Y-
1140 of Kluyveromyces lactis - Kluyveromyces lactis
(Yeast) (Candida sphaerica)
Length = 2889
Score = 80.6 bits (190), Expect = 2e-13
Identities = 71/290 (24%), Positives = 130/290 (44%), Gaps = 19/290 (6%)
Query: 636 TDRQPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHC 695
+D LA+S++ F + EL E+ H + R S AT L R
Sbjct: 1507 SDIDALASSIVYFFDVKNAAHIIVTELVREEIGNATRHMEILRRNSCATRALSMLARLKG 1566
Query: 696 KPFLQAAISETIQKLIDSKQ---TAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSP 752
+L + +++LI+SK+ +L+P +D+P + +++ ++D IT S+
Sbjct: 1567 MDYLSNILKPILEELINSKECFDVEKLDPNDVDAPRNLMLFKKYMTKVVDAITGSV---- 1622
Query: 753 EACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPP 812
++ P +C + +A ++P + V F+FLR CPALV P + +V +
Sbjct: 1623 DSFPPQFFVICQAIHSSASERFPEYADI---AVGSFLFLRFFCPALVSPDSEEIVD-SLT 1678
Query: 813 PHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNS 872
P A++S + +AK +QN+AN K +E + F+ ++ FL +S+ N
Sbjct: 1679 PKARKSSMSLAKVIQNIANGSVNSIKWKILESESEFLKNCSNKIFEFLSVVSD----KNR 1734
Query: 873 PPNSNVNFE---IAKELATLHHICVAHLTELQ-GLAKNQPAIRKLVTVTE 918
N+ + + E + LH H E++ L ++ + L TV E
Sbjct: 1735 KVKINLRMQNRVLPNEFSFLHKFLYYHGLEMRNALIEDIKSFDDLATVRE 1784
>UniRef50_UPI000049A418 Cluster: Ras GTPase activating protein; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: Ras GTPase
activating protein - Entamoeba histolytica HM-1:IMSS
Length = 660
Score = 80.2 bits (189), Expect = 2e-13
Identities = 56/239 (23%), Positives = 105/239 (43%), Gaps = 4/239 (1%)
Query: 627 VKALADLCRTDRQPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAV 686
V ++ C D P ++ N L ++ EV D LFR T +
Sbjct: 50 VSSIIRTCGVDAVPFWDAIRNCLDSDAVLIYLLKQHITEEVRNTKDKAQLFRANGGFTHL 109
Query: 687 LDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITL 746
+ FM+ K L+ I+ I+ + + E++ TK+ S + N E LL IL +
Sbjct: 110 MSSFMKKEGKKILEEYINPIIKVVNEQPNELEVDNTKV-SQEVVDKNIETLLTILKEHVC 168
Query: 747 SIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTL 806
+ Y+ +++ + KWP + + GF+FLR I PA+V P +
Sbjct: 169 KFDILSKLISPDFSYIFNVIKKEVMKKWPENALI---AIGGFLFLRFINPAIVSPHRFGS 225
Query: 807 VQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSN 865
P + R+L++++K +Q++AN +E M+ + ++L + + FL+ +S+
Sbjct: 226 NMLLPNDNGHRTLILISKVVQSIANQPLCPFREECMQPFSDYVLSQYDHVNQFLNIISS 284
>UniRef50_A7S5U4 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 765
Score = 80.2 bits (189), Expect = 2e-13
Identities = 44/124 (35%), Positives = 71/124 (57%), Gaps = 3/124 (2%)
Query: 748 IFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTR-VVSGFIFLRLICPALVEPRAWTL 806
I +S P +++LC ++ A+ K+P + ++ GF LR I PA+V P A+ L
Sbjct: 254 IISSLSQVPYGIQWLCRAIKELAMEKFPEATPEQINAMIGGFFLLRFINPAIVTPTAYML 313
Query: 807 VQRAPPPHAQRSLLMVAKCLQNLA--NLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLS 864
V + P +R+L ++AK LQ++A N+V KE YM+ + PF + + + M FL LS
Sbjct: 314 VNKQPTYTMRRNLTLIAKILQSMANKNVVSSHFKEEYMQPLQPFAINHVDLMQSFLSDLS 373
Query: 865 NVPD 868
+VPD
Sbjct: 374 SVPD 377
>UniRef50_Q6FNM9 Cluster: Candida glabrata strain CBS138 chromosome
J complete sequence; n=1; Candida glabrata|Rep: Candida
glabrata strain CBS138 chromosome J complete sequence -
Candida glabrata (Yeast) (Torulopsis glabrata)
Length = 1068
Score = 80.2 bits (189), Expect = 2e-13
Identities = 47/198 (23%), Positives = 103/198 (52%), Gaps = 9/198 (4%)
Query: 675 TLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDA---- 730
+LFRG S+ T L+ + + +L+ A I+ L++ + + E++P ++ + DD
Sbjct: 575 SLFRGNSILTKTLELYFLRIGREYLEKAFGTLIRNLLNEEVSFEMDPMRISAKDDIERRQ 634
Query: 731 --CNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRA--AVAKWPNERFVRTRVVS 786
+N+E L + I I + PK ++ L++ + ++ + +S
Sbjct: 635 IIQHNSEDLKQWVCTIWNRIIETSNDLPKKIKKQLHELRKGFEIICLEKGQQSI-LNCIS 693
Query: 787 GFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVN 846
F+FLR CP ++ P+ + + R++L++ K LQN++ L FG KE +++ +N
Sbjct: 694 AFLFLRFFCPLILNPKLFKFTESHLTMKQTRNMLLITKVLQNISTLNPFGVKEQWLQPLN 753
Query: 847 PFILKNKERMVVFLDQLS 864
PF+ +E+++ ++D+++
Sbjct: 754 PFVEGFREQVIEYVDKVT 771
>UniRef50_A5E1X9 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 2712
Score = 79.8 bits (188), Expect = 3e-13
Identities = 54/191 (28%), Positives = 92/191 (48%), Gaps = 10/191 (5%)
Query: 641 LATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQ 700
LA+S+ + FA L +EL C E++ LFR S T +L + + + +L
Sbjct: 1351 LASSLYSVFAYTHNLEGLFKELLCDEISNLTRASDLFRRNSTLTRLLFNITQEYGQNYLN 1410
Query: 701 AAISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVR 760
I +++++D++ E+ K ++ +D+ F + IT S+ PEA +
Sbjct: 1411 KTICPIVKEIVDTEVYFEVE--KRETTEDSAKFIHFFEQTVQLITDSLEDLPEA----FK 1464
Query: 761 YLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLL 820
Y+C + AK+ N V F+FLR ICPA++ P + + P +RSL+
Sbjct: 1465 YVCHVISETVSAKFEN---AALSAVGSFLFLRFICPAVISPEQFFKIP-VENPKTKRSLM 1520
Query: 821 MVAKCLQNLAN 831
+ K LQN+AN
Sbjct: 1521 QIVKVLQNIAN 1531
>UniRef50_Q55AR6 Cluster: Putative uncharacterized protein; n=2;
Dictyostelium discoideum|Rep: Putative uncharacterized
protein - Dictyostelium discoideum AX4
Length = 920
Score = 78.2 bits (184), Expect = 1e-12
Identities = 70/247 (28%), Positives = 115/247 (46%), Gaps = 28/247 (11%)
Query: 644 SVLNTFAECGRGAELARELTCAE----VAREGDHKTLFRGASLATAVLDEFMRAHCKPFL 699
+++N F + L ++L E V EG+ L RG S+ + ++R +L
Sbjct: 54 NIVNIFTTANKTLPLIKDLIYNEFNTKVLAEGEGSIL-RGNSIVNKIEGAYVRLIGANYL 112
Query: 700 QAAISETIQKLI-DSKQTAELNPTKM-DSPDDAC------------NNAEFLLMILDQIT 745
+ +S+ + K++ DS E++P K+ D +D +N + L I Q
Sbjct: 113 RFVLSDLVTKVVLDSDLKLEIDPRKLNDYYEDKIEFEKKVAEVELRDNQKSLHNIAQQF- 171
Query: 746 LSIFTSPEAC---PKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPR 802
L T P P+ +R + +A+ P +V GFI LR PA+V P
Sbjct: 172 LDRITDPSVVVEMPREIRAIADYTAESALRYAPESL---APLVGGFIMLRFFSPAIVTPE 228
Query: 803 AWTLVQR--APPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFL 860
L+ AP A+R+L+++AK LQN +N V FG KE +M +N FI+ NKE+M +
Sbjct: 229 YSKLLSSEVAPSKRAKRNLVLLAKVLQNASNGVLFGGKEEFMTCMNDFIIGNKEKMSAYF 288
Query: 861 DQLSNVP 867
+ + P
Sbjct: 289 NLICKDP 295
>UniRef50_P19158 Cluster: Inhibitory regulator protein IRA2; n=2;
Saccharomyces cerevisiae|Rep: Inhibitory regulator
protein IRA2 - Saccharomyces cerevisiae (Baker's yeast)
Length = 3079
Score = 77.4 bits (182), Expect = 2e-12
Identities = 54/228 (23%), Positives = 103/228 (45%), Gaps = 5/228 (2%)
Query: 636 TDRQPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHC 695
+D A ++N F + +L E+ + + R S AT L R+
Sbjct: 1700 SDIDAYAAGLINAFETRNATHIVVAQLIKNEIEKSSRPTDILRRNSCATRSLSMLARSKG 1759
Query: 696 KPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEAC 755
+L + ++K+I ++ E+ K + DA E + ++++ SI S
Sbjct: 1760 NEYLIRTLQPLLKKIIQNRDFFEIEKLKPED-SDAERQIELFVKYMNELLESISNSVSYF 1818
Query: 756 PKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHA 815
P P+ Y+C + + A K+P+ + F+FLR CPALV P + ++ +
Sbjct: 1819 PPPLFYICQNIYKVACEKFPDHAII---AAGSFVFLRFFCPALVSPDSENIIDISHLSE- 1874
Query: 816 QRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQL 863
+R+ + +AK +QN+AN E ++ P + F+ + +R+ FL +L
Sbjct: 1875 KRTFISLAKVIQNIANGSENFSRWPALCSQKDFLKECSDRIFRFLAEL 1922
>UniRef50_A7TN87 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 3034
Score = 77.0 bits (181), Expect = 2e-12
Identities = 57/220 (25%), Positives = 98/220 (44%), Gaps = 5/220 (2%)
Query: 658 LARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTA 717
L +L E+ H + R S+AT L + R+ +L I ++++++ K
Sbjct: 1674 LITQLVKDEIQDSIRHMDILRRNSVATRALSLYSRSKGNEYLVKIIGPVLEQMVEDKAYF 1733
Query: 718 ELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNE 777
E+ ++D P+ A + + + +I S + P + +C + K+P
Sbjct: 1734 EVEKLQLDDPN-ASEQLDLFEKYMKILIDAIIGSIDCFPVELFVVCQVIYSEVRKKFPEY 1792
Query: 778 RFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGA 837
V V F+FLR ICPALV P ++ P +RSL+ +AK +QN+AN +
Sbjct: 1793 SLV---AVGSFVFLRFICPALVSPETENII-GVTPLKEKRSLIQMAKVIQNMANGSDNLL 1848
Query: 838 KEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSN 877
K P + F+ K + + FL +LS P NS+
Sbjct: 1849 KWPSLATKLDFLKKCNDDIFEFLAELSRTDRVIKIPLNSS 1888
>UniRef50_Q757I8 Cluster: AER025Cp; n=2; Eukaryota|Rep: AER025Cp -
Ashbya gossypii (Yeast) (Eremothecium gossypii)
Length = 2911
Score = 73.3 bits (172), Expect = 3e-11
Identities = 63/261 (24%), Positives = 115/261 (44%), Gaps = 11/261 (4%)
Query: 610 EEYNPLRQLLLEPGIPAVKALADLCRT----DRQPLATSVLNTFAECGRGAELARELTCA 665
EE + + LL+ + K L+ R D LA S + + + EL
Sbjct: 1506 EERSAAIETLLDRAVEDPKLLSKAARVCPANDIDSLAGSFVTLYDIKNAAHLIVIELIID 1565
Query: 666 EVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMD 725
E++R + + R S AT L F R +L + +++++ + +T ++ + D
Sbjct: 1566 EISRATRYMDVLRRNSCATRSLSMFSRLKGGAYLINVLKPVLEEVVATGETFDVEKIEPD 1625
Query: 726 SPDDACN-NAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRV 784
PD C + + L+++ SI S P +C + + +P+ +
Sbjct: 1626 DPD--CQIHVDLFCKYLNKLVDSIVGSVADFPPEFFVICQSIYSSVKENFPDSAEI---A 1680
Query: 785 VSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEV 844
V FIFLR CPALV P + + P A+RS +++AK +QN+AN K P ++
Sbjct: 1681 VGSFIFLRFFCPALVSPDSEGITDPLYPK-ARRSFMILAKVIQNIANGSVSSLKWPALQS 1739
Query: 845 VNPFILKNKERMVVFLDQLSN 865
F+ +R+ +L ++S+
Sbjct: 1740 EVEFLKTISDRIFCYLKEISD 1760
>UniRef50_A3GHY3 Cluster: Ras GTPase activating protein
RasGAP/neurofibromin; n=1; Pichia stipitis|Rep: Ras
GTPase activating protein RasGAP/neurofibromin - Pichia
stipitis (Yeast)
Length = 2643
Score = 73.3 bits (172), Expect = 3e-11
Identities = 51/204 (25%), Positives = 97/204 (47%), Gaps = 12/204 (5%)
Query: 629 ALADLCR-TDRQPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVL 687
A+A++ T+ LA+S+ F+ + L + L EV +FR S+ T +L
Sbjct: 1280 AIAEVASSTEHNLLASSLFGIFSYTKKLDNLFKVLLYDEVNTVSRSTDIFRRNSVLTRLL 1339
Query: 688 DEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLS 747
+ R H +L+ + I+ +++++ E+ K+D D + +++ S
Sbjct: 1340 SNYARDHGLDYLENTLKPVIEDIVNNEVIFEVE--KVDQGDSVV-----FMKYFNKLVDS 1392
Query: 748 IFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLV 807
I S E+ P +++C + R K+ + + V F+FLR +CPA++ P A+ +
Sbjct: 1393 IVLSAESLPDSFKFICAEVYRCVQKKFEDAALI---AVGSFVFLRFLCPAIISPEAFFGI 1449
Query: 808 QRAPPPHAQRSLLMVAKCLQNLAN 831
P +R+L+ + K LQN AN
Sbjct: 1450 -NVTNPKVKRTLMQLVKVLQNTAN 1472
>UniRef50_Q4V9Q1 Cluster: Zgc:109892; n=11; Euteleostomi|Rep:
Zgc:109892 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 214
Score = 70.1 bits (164), Expect = 3e-10
Identities = 42/142 (29%), Positives = 76/142 (53%), Gaps = 10/142 (7%)
Query: 179 DTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHP 238
+ DEL+FQKG+I V N M D W TA G +G + + + ++ P+T WF
Sbjct: 13 ECDELSFQKGEILKVTN-MDDDPNWYTAELLGRRGYVPKNYI-----NVRPHT---WFVG 63
Query: 239 NCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV-RYLMGGRT 297
++ A + L G+FL+R S+++PG++S+ + +Q F++ K G+ +Y +
Sbjct: 64 GISRQAAENRLRPLECGAFLIRESESTPGEFSVSVSYGDHVQHFKVLKDGLGQYFIWDEV 123
Query: 298 FECLDAVINRYRKEQIVEGHTL 319
F L+ +++ YR I + T+
Sbjct: 124 FSSLNQLVDFYRINSIAKERTV 145
Score = 54.4 bits (125), Expect = 1e-05
Identities = 47/163 (28%), Positives = 72/163 (44%), Gaps = 8/163 (4%)
Query: 62 PETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VC 120
P T W+ G + R +E RL + G++L+RES+ PG + +S + HF++
Sbjct: 57 PHT-WFVGGISRQAAENRL-RPLECGAFLIRESESTPGEFSVSVSYGDHVQHFKVLKDGL 114
Query: 121 GDYYIGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDT 180
G Y+I F SL +LV FY S + +ER + AI +T T
Sbjct: 115 GQYFIWDEVFSSLNQLVDFYRINS--IAKERTVFLRDPEGSLARPRHAHAIFDFTSNHVT 172
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDL 223
L F +GD+ + D D W R G G+ E V+ +
Sbjct: 173 -HLCFLRGDVIDL-LDCSDAQCWRGRCR-GRVGIFPPEYVQPI 212
>UniRef50_P18963 Cluster: Inhibitory regulator protein IRA1; n=2;
Saccharomyces cerevisiae|Rep: Inhibitory regulator
protein IRA1 - Saccharomyces cerevisiae (Baker's yeast)
Length = 3092
Score = 69.7 bits (163), Expect = 3e-10
Identities = 54/226 (23%), Positives = 102/226 (45%), Gaps = 5/226 (2%)
Query: 642 ATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQA 701
A LN F L EL E+ R + R S AT L + R+ +L
Sbjct: 1714 AGGFLNAFDTRNASHILVTELLKQEIKRAARSDDILRRNSCATRALSLYTRSRGNKYLIK 1773
Query: 702 AISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRY 761
+ +Q ++D+K++ E++ K S +++ + + ++ +I +S + P +
Sbjct: 1774 TLRPVLQGIVDNKESFEIDKMKPGS-ENSEKMLDLFEKYMTRLIDAITSSIDDFPIELVD 1832
Query: 762 LCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLM 821
+C + AA +P ++ V F+FLR I PALV P + ++ H ++ +
Sbjct: 1833 ICKTIYNAASVNFPEYAYI---AVGSFVFLRFIGPALVSPDSENII-IVTHAHDRKPFIT 1888
Query: 822 VAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVP 867
+AK +Q+LAN E K+ + F+ +++ FL +L +P
Sbjct: 1889 LAKVIQSLANGRENIFKKDILVSKEEFLKTCSDKIFNFLSELCKIP 1934
>UniRef50_Q6FJ13 Cluster: Candida glabrata strain CBS138 chromosome M
complete sequence; n=2; Eukaryota|Rep: Candida glabrata
strain CBS138 chromosome M complete sequence - Candida
glabrata (Yeast) (Torulopsis glabrata)
Length = 3124
Score = 69.3 bits (162), Expect = 4e-10
Identities = 58/257 (22%), Positives = 108/257 (42%), Gaps = 5/257 (1%)
Query: 615 LRQLLLEPGIPAVKALADLCRTDRQPLATSVLNTFAECGRGAELARELTCAEVAREGDHK 674
L Q L+E A +A +D ++N F L +L E+ R +
Sbjct: 1724 LVQYLIEHPHLAFQAGIICPASDVDAFVAGLVNGFDSRNASHILVTQLIKDEIDRASRYA 1783
Query: 675 TLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACNNA 734
+ R S AT L + R+ + +L + + + +S+ + E+ D P+ A N
Sbjct: 1784 DVLRRNSCATRALSLYARSKGQSYLVRTLKPVLDEFFESRDSFEIEKILPDDPE-AEKNV 1842
Query: 735 EFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLI 794
+ + + ++ +I S + P + +C + + K+P+ F+ V F+FLR +
Sbjct: 1843 DMFIHYMSKLINAITESVDYFPPELINICQTIFHSVKEKFPDYSFI---AVGSFVFLRFL 1899
Query: 795 CPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKE 854
PA+V P A ++ +R L+ +AK LQN+AN E + P +
Sbjct: 1900 GPAIVSPDAENII-LISQTRDKRPLITLAKVLQNMANGSENLTRWPILNKKLDIFKDFSN 1958
Query: 855 RMVVFLDQLSNVPDPGN 871
R+ FL ++ + N
Sbjct: 1959 RIFEFLSKICTIDSKPN 1975
>UniRef50_Q5A3W3 Cluster: Putative uncharacterized protein IRA2; n=2;
Candida albicans|Rep: Putative uncharacterized protein
IRA2 - Candida albicans (Yeast)
Length = 2643
Score = 69.3 bits (162), Expect = 4e-10
Identities = 52/191 (27%), Positives = 86/191 (45%), Gaps = 10/191 (5%)
Query: 641 LATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQ 700
LA++ F+ G+ L L EVA LFR S T L + + + +L
Sbjct: 1283 LASAFFEVFSYTGKLNNLFNVLLNTEVALSSRSTDLFRRNSTLTKFLSFYAQTNGVDYLN 1342
Query: 701 AAISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVR 760
+ I++L+D+ E+ K D+ D A+ ++ L +I SI S + P +
Sbjct: 1343 EVLLPVIKELVDNDVQFEVE--KQDNSD----TADLFILYLSRIIDSIVNSTDKLPHAFK 1396
Query: 761 YLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLL 820
+ + + K+P VS F+FLR +CPA++ P + P +RSL+
Sbjct: 1397 SVSKAIYDSVSNKFPEAALT---AVSSFVFLRFLCPAIISPEQHFKLP-INNPKVKRSLM 1452
Query: 821 MVAKCLQNLAN 831
+ K LQN+AN
Sbjct: 1453 QLVKVLQNMAN 1463
>UniRef50_Q5F3D9 Cluster: Putative uncharacterized protein; n=2;
Gallus gallus|Rep: Putative uncharacterized protein -
Gallus gallus (Chicken)
Length = 558
Score = 68.5 bits (160), Expect = 8e-10
Identities = 66/261 (25%), Positives = 112/261 (42%), Gaps = 19/261 (7%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
VH S+ ++FCFQ++ + +F ++ A +R WIE LR P + C+
Sbjct: 297 VHGSIVGEKFCFQIITGG----HSRSFGCSSLAERDR-WIENLRRTVQPN--KDNCERLE 349
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPR---PSPDPHWXXXXXXXX 537
++ LW+ A LP R R HL L ART + P + W
Sbjct: 350 LALSLWV----YEARDLPPRRRLRCHLH--LDGTLFARTTAKVAGPDGELFWGELFQLAA 403
Query: 538 MPPDVTSLTITVHNTGKRGKESEVAELTIELANLANGEE-IEEWYPLVGMTPIGEWGSLR 596
+PP +LT+++ + VA +T+ L LA + +E WYPL G ++R
Sbjct: 404 LPPS-RALTLSLCRDDQGHPSQTVASVTVPLTELAAARQPLERWYPLSGHGGNERAPAVR 462
Query: 597 LRIRYMQELVMPREEYNPLRQLL-LEPGIPAVKALADLCRTDRQPLATSVLNTFAECGRG 655
+R RY + V+P Y L + + + + ++ LA +++ G+
Sbjct: 463 VRGRYREVRVLPIVRYKELAEFITFHYRELCARLEPTIAVRHKEELAGALVRVLQSTGKA 522
Query: 656 AELARELTCAEVAREGDHKTL 676
E +L AE+ R D ++L
Sbjct: 523 KEFLIDLGVAELDRFDDRESL 543
>UniRef50_UPI0000498B16 Cluster: Ras GTPase activating protein; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: Ras GTPase
activating protein - Entamoeba histolytica HM-1:IMSS
Length = 604
Score = 67.7 bits (158), Expect = 1e-09
Identities = 53/198 (26%), Positives = 94/198 (47%), Gaps = 11/198 (5%)
Query: 670 EGDHKTLFRGASLATAVLDEF-MRAHCKPFLQAAISETIQKLIDSK-QTAELNPTKMDSP 727
+ ++ T+FRG S + L + + ++ + + E + K++ + + E+NP P
Sbjct: 64 KSENGTMFRGNSFCSRCLTVYTLMTMSNQYVISFLEEPMTKVLKGEYKNLEINPDFAIGP 123
Query: 728 DDACNNAEFLLMILDQITLS-IFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVS 786
D + F L + QI ++ I + P+ RYLC L + + VS
Sbjct: 124 ID---ESIFKLKEIVQIFITRIIDTINLWPESYRYLCYSLYSECEKTTTLQPL---QCVS 177
Query: 787 GFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVN 846
GF+ LR+ICPA+++P P R L+M+ K +QN+AN EPYM+ ++
Sbjct: 178 GFLVLRVICPAIMQPHKTGFCNEKPNNDIMRGLIMICKVIQNIANGTL--PHEPYMKCLS 235
Query: 847 PFILKNKERMVVFLDQLS 864
FI K + L+++S
Sbjct: 236 EFISKETIALQFALEKIS 253
>UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2;
n=3; Mammalia|Rep: Growth factor receptor bound protein
2 - Mus musculus (Mouse)
Length = 203
Score = 66.5 bits (155), Expect = 3e-09
Identities = 45/147 (30%), Positives = 76/147 (51%), Gaps = 12/147 (8%)
Query: 170 AILPYT-KMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
AI Y K DEL+F++GDI V N+ D W A G+ G I + +E +
Sbjct: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQ-NWYKAELNGKDGFIPKNYIE-----MK 56
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKK 287
P+ WF +++A +ML K G+FL+R S+++PGD+SL N +Q F++ +
Sbjct: 57 PHP---WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRD 113
Query: 288 GV-RYLMGGRTFECLDAVINRYRKEQI 313
G +Y + F L+ +++ +R +
Sbjct: 114 GAGKYFLWVVKFNSLNELVDYHRSTSV 140
Score = 57.6 bits (133), Expect = 1e-06
Identities = 44/164 (26%), Positives = 75/164 (45%), Gaps = 22/164 (13%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDYY 124
W+ G++ R +EE L G++L+RES+ PG + LS + HF++ G Y+
Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTD-EL 183
+ +F+SL ELV + H S + R + + + +MP D EL
Sbjct: 120 LWVVKFNSLNELVDY--HRSTSVSR----------------NQQIFLRDIEQMPQEDGEL 161
Query: 184 TFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
F++GD V ++ W H G+ GM R V ++ ++
Sbjct: 162 GFRRGDFIHVMDNSDPNWWKGACH--GQTGMFPRNYVTPVNRNV 203
>UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2;
n=26; Euteleostomi|Rep: Growth factor receptor-bound
protein 2 - Homo sapiens (Human)
Length = 217
Score = 66.5 bits (155), Expect = 3e-09
Identities = 45/147 (30%), Positives = 76/147 (51%), Gaps = 12/147 (8%)
Query: 170 AILPYT-KMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
AI Y K DEL+F++GDI V N+ D W A G+ G I + +E +
Sbjct: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQ-NWYKAELNGKDGFIPKNYIE-----MK 56
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKK 287
P+ WF +++A +ML K G+FL+R S+++PGD+SL N +Q F++ +
Sbjct: 57 PHP---WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRD 113
Query: 288 GV-RYLMGGRTFECLDAVINRYRKEQI 313
G +Y + F L+ +++ +R +
Sbjct: 114 GAGKYFLWVVKFNSLNELVDYHRSTSV 140
Score = 66.5 bits (155), Expect = 3e-09
Identities = 44/163 (26%), Positives = 74/163 (45%), Gaps = 6/163 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDYY 124
W+ G++ R +EE L G++L+RES+ PG + LS + HF++ G Y+
Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTDELT 184
+ +F+SL ELV + H S + R + V A+ + D EL
Sbjct: 120 LWVVKFNSLNELVDY--HRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQED-GELG 176
Query: 185 FQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
F++GD V ++ W H G+ GM R V ++ ++
Sbjct: 177 FRRGDFIHVMDNSDPNWWKGACH--GQTGMFPRNYVTPVNRNV 217
>UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to
protein-tyrosine phosphatase; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to protein-tyrosine
phosphatase - Strongylocentrotus purpuratus
Length = 533
Score = 66.1 bits (154), Expect = 4e-09
Identities = 34/81 (41%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVC 120
P W+HG + +E+ L K GSYLVRES KPG YVLS + H I
Sbjct: 107 PTNERWFHGHITGKEAEKSLVDKGKNGSYLVRESHSKPGDYVLSVRTEDKVTHVMIRCQD 166
Query: 121 GDYYI-GGRQFDSLTELVGFY 140
Y + GG QF++LT+LV Y
Sbjct: 167 TKYDVGGGEQFETLTDLVDHY 187
Score = 58.8 bits (136), Expect = 6e-07
Identities = 32/83 (38%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFH + T EA LV G GS+LVR S + PGDY L +++ I + +Y +
Sbjct: 112 WFHGHITGKEAEKSLVDKGKNGSYLVRESHSKPGDYVLSVRTEDKVTHVMIRCQDTKYDV 171
Query: 293 MGGRTFECLDAVINRYRKEQIVE 315
GG FE L +++ YRK +VE
Sbjct: 172 GGGEQFETLTDLVDHYRKNPMVE 194
Score = 57.2 bits (132), Expect = 2e-06
Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFHPN + EA +L+ G G FL RPS ++PGD++L N ++ +I+ G + L
Sbjct: 6 WFHPNISGMEAEQLLLNNGFDGCFLCRPSKSNPGDFTLSVRRNGEVTHIKIQNTGDFFDL 65
Query: 293 MGGRTFECLDAVINRY 308
GG F L ++ Y
Sbjct: 66 YGGEKFATLAELVQHY 81
Score = 45.2 bits (102), Expect = 0.008
Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H + +E+ L G +L R S PG + LS + H +I GD++
Sbjct: 6 WFHPNISGMEAEQLLLNNGFDGCFLCRPSKSNPGDFTLSVRRNGEVTHIKIQNT-GDFFD 64
Query: 125 -IGGRQFDSLTELVGFYSHCSDLLK 148
GG +F +L ELV Y+ + LK
Sbjct: 65 LYGGEKFATLAELVQHYTEGRNQLK 89
>UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6;
Endopterygota|Rep: Tyrosine-protein kinase Src64B -
Drosophila melanogaster (Fruit fly)
Length = 552
Score = 66.1 bits (154), Expect = 4e-09
Identities = 52/166 (31%), Positives = 80/166 (48%), Gaps = 13/166 (7%)
Query: 166 KRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDP 225
KRVV L K D +L+F KGD V +D W V T ++G+I V + +
Sbjct: 97 KRVVVALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAE-ER 155
Query: 226 SIDPNTVFSWFHPNCTKSEAVDMLV-KAGP-GSFLVRPSDNSPGDYSLFFH-----INNQ 278
S++ WF N + EA +L+ + P G+FLVRPS+++P YSL
Sbjct: 156 SVNSE---DWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYH 212
Query: 279 IQRFRIE--KKGVRYLMGGRTFECLDAVINRYRKEQIVEGHTLGQP 322
++ +RI+ G Y+ +TF L A++ Y K + H L +P
Sbjct: 213 VKHYRIKPLDNGGYYIATNQTFPSLQALVMAYSKNALGLCHILSRP 258
>UniRef50_UPI000058445F Cluster: PREDICTED: similar to SH2/SH3
adaptor protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to SH2/SH3 adaptor protein -
Strongylocentrotus purpuratus
Length = 389
Score = 65.7 bits (153), Expect = 5e-09
Identities = 28/78 (35%), Positives = 46/78 (58%)
Query: 63 ETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGD 122
+ +W+HGR+ R SE+ L + G +L+RES+ PG + +S + HF++T
Sbjct: 288 DRDWFHGRITRQDSEKILGCPGESGLFLIRESETMPGDFAVSVKAPERVKHFKVTRSDKK 347
Query: 123 YYIGGRQFDSLTELVGFY 140
+ IG R+F+SL +LV Y
Sbjct: 348 FCIGQRKFESLDDLVDHY 365
Score = 55.6 bits (128), Expect = 6e-06
Identities = 23/80 (28%), Positives = 46/80 (57%), Gaps = 1/80 (1%)
Query: 235 WFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLM 293
WFH T+ ++ +L G G FL+R S+ PGD+++ +++ F++ + ++ +
Sbjct: 291 WFHGRITRQDSEKILGCPGESGLFLIRESETMPGDFAVSVKAPERVKHFKVTRSDKKFCI 350
Query: 294 GGRTFECLDAVINRYRKEQI 313
G R FE LD +++ Y++ I
Sbjct: 351 GQRKFESLDDLVDHYKRSPI 370
>UniRef50_A3LZE1 Cluster: GTPase-activating protein; n=3;
Saccharomycetaceae|Rep: GTPase-activating protein -
Pichia stipitis (Yeast)
Length = 1165
Score = 65.3 bits (152), Expect = 7e-09
Identities = 37/135 (27%), Positives = 72/135 (53%), Gaps = 2/135 (1%)
Query: 732 NNAEFLLMILDQITLSIFTSPEACPKPVRY-LCGCLQRAAVAKWPNERFVRTRVVSGFIF 790
+N E L ++++ I+ + P ++ L + +A P+++ +S FIF
Sbjct: 748 DNFENLYDYVEEVWHKIYITSNDLPAQIKIQLKNFRTKVELACDPDDKTTPLNCLSAFIF 807
Query: 791 LRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGA-KEPYMEVVNPFI 849
LR CPA++ P+ + L + QR+L ++AK L N AN EF KEP++ +N F+
Sbjct: 808 LRFFCPAILNPKLFYLTKNHQSGTTQRTLTLIAKILLNFANRQEFTKHKEPHLLRMNKFL 867
Query: 850 LKNKERMVVFLDQLS 864
K+++ + + D+++
Sbjct: 868 KKHRKEIYDYFDKIT 882
>UniRef50_UPI00015A7910 Cluster: hypothetical protein LOC553596;
n=2; Danio rerio|Rep: hypothetical protein LOC553596 -
Danio rerio
Length = 283
Score = 64.9 bits (151), Expect = 1e-08
Identities = 40/142 (28%), Positives = 75/142 (52%), Gaps = 10/142 (7%)
Query: 179 DTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHP 238
++DEL+FQKGD+ + N M D W TA +G + + + S+ P+ +WF
Sbjct: 13 ESDELSFQKGDVLKITN-MEDDPNWYTAEFVNRKGYVPKNYI-----SLRPH---AWFAG 63
Query: 239 NCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK-KGVRYLMGGRT 297
++ A + L + GSFLVR S+++PG++S+ + +Q F++ K + Y +
Sbjct: 64 RISRHVAENRLHQRDCGSFLVRESESAPGEFSMSVSYGDHVQHFKVLKDREGYYFVWEEI 123
Query: 298 FECLDAVINRYRKEQIVEGHTL 319
F L+ +++ Y+ I + T+
Sbjct: 124 FPSLNQLVDYYKTNSIAKERTV 145
Score = 51.2 bits (117), Expect = 1e-04
Identities = 27/76 (35%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVC-GDYY 124
W+ GR+ R+ +E RL GS+LVRES+ PG + +S + HF++ G Y+
Sbjct: 60 WFAGRISRHVAENRLHQRDC-GSFLVRESESAPGEFSMSVSYGDHVQHFKVLKDREGYYF 118
Query: 125 IGGRQFDSLTELVGFY 140
+ F SL +LV +Y
Sbjct: 119 VWEEIFPSLNQLVDYY 134
>UniRef50_Q9VXH3 Cluster: CG4200-PA; n=5; Drosophila|Rep: CG4200-PA
- Drosophila melanogaster (Fruit fly)
Length = 1236
Score = 64.9 bits (151), Expect = 1e-08
Identities = 35/92 (38%), Positives = 49/92 (53%)
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMG 294
WFHPN TK +A L + GSFLVRPS S + + F IN +I+ RI ++G Y +
Sbjct: 701 WFHPNTTKEQAEQGLYRLEIGSFLVRPSVQSINAFVISFTINRKIKHCRIMQEGRLYGID 760
Query: 295 GRTFECLDAVINRYRKEQIVEGHTLGQPLIAE 326
FE L ++IN Y + + L P+ E
Sbjct: 761 TMNFESLVSLINYYTRNPLYRNVKLSHPVSQE 792
Score = 43.2 bits (97), Expect = 0.033
Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
Query: 63 ETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGD 122
+ EW+H + +E+ L+ + GS+LVR S + ++V+S+ I H RI
Sbjct: 698 DQEWFHPNTTKEQAEQGLYRL-EIGSFLVRPSVQSINAFVISFTINRKIKHCRIMQEGRL 756
Query: 123 YYIGGRQFDSLTELVGFYS 141
Y I F+SL L+ +Y+
Sbjct: 757 YGIDTMNFESLVSLINYYT 775
Score = 42.7 bits (96), Expect = 0.044
Identities = 33/90 (36%), Positives = 44/90 (48%), Gaps = 10/90 (11%)
Query: 234 SWFHPNCT--KSEAVDMLVKA---GPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKG 288
+WFH + EA D+L K G G+FLVR S GDYSL F N+ RI+ K
Sbjct: 588 NWFHGKLEGGRKEADDLLKKYKHFGDGTFLVRESATFVGDYSLSFWRRNRPNHCRIKLKH 647
Query: 289 VR-----YLMGGRTFECLDAVINRYRKEQI 313
YL+ F+ L ++I YRK +
Sbjct: 648 ENGSIKYYLVENFVFDSLYSLIVYYRKNML 677
Score = 37.9 bits (84), Expect = 1.3
Identities = 28/84 (33%), Positives = 41/84 (48%), Gaps = 9/84 (10%)
Query: 66 WYHGRLD--RYTSEERL--WAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI----- 116
W+HG+L+ R +++ L + G++LVRES G Y LS+ R NH RI
Sbjct: 589 WFHGKLEGGRKEADDLLKKYKHFGDGTFLVRESATFVGDYSLSFWRRNRPNHCRIKLKHE 648
Query: 117 TAVCGDYYIGGRQFDSLTELVGFY 140
Y + FDSL L+ +Y
Sbjct: 649 NGSIKYYLVENFVFDSLYSLIVYY 672
>UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21;
Bilateria|Rep: GRB2-related adapter protein - Homo
sapiens (Human)
Length = 217
Score = 64.9 bits (151), Expect = 1e-08
Identities = 44/157 (28%), Positives = 69/157 (43%), Gaps = 4/157 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDYY 124
WY GR+ R +EE L + G++L+RES+ PG + +S + HF++ G Y+
Sbjct: 60 WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYF 119
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTDELT 184
+ +F+SL ELV FY + KR+ A ++ D +L+
Sbjct: 120 LWEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEPLLKSPGACFAQAQFDFSAQ-DPSQLS 178
Query: 185 FQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVE 221
F++GDI V W W G G R V+
Sbjct: 179 FRRGDIIEVLERPDPHW-W-RGRSCGRVGFFPRSYVQ 213
Score = 62.5 bits (145), Expect = 5e-08
Identities = 38/139 (27%), Positives = 73/139 (52%), Gaps = 11/139 (7%)
Query: 179 DTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHP 238
++DEL F KGD + N M D W A G +G I + + + P+ W+
Sbjct: 13 ESDELAFNKGDTLKILN-MEDDQNWYKAELRGVEGFIPKNYIR-----VKPHP---WYSG 63
Query: 239 NCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV-RYLMGGR 296
++ A ++L+K G+FL+R S++SPG++S+ + +Q+Q F++ ++ +Y +
Sbjct: 64 RISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFLWEE 123
Query: 297 TFECLDAVINRYRKEQIVE 315
F L+ +++ YR I +
Sbjct: 124 KFNSLNELVDFYRTTTIAK 142
>UniRef50_Q6PE32 Cluster: Zgc:65942; n=2; Danio rerio|Rep: Zgc:65942
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 249
Score = 64.5 bits (150), Expect = 1e-08
Identities = 39/135 (28%), Positives = 67/135 (49%), Gaps = 14/135 (10%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNC 240
DEL+F+KGD+ + D W A G +G + R + PS W+ N
Sbjct: 15 DELSFRKGDVIKILGTNDD---WFRAEINGMEGFVPRNYIVTTFPS--------WYKENT 63
Query: 241 TKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGGRTF 298
++ A D L+ G+F++R S +SPGD+S+ N +Q F++ +++G RY + F
Sbjct: 64 SRQSAQDELMCQPIGAFIIRGSQSSPGDFSISVRHENDVQHFKVMRDRQG-RYYLWSEMF 122
Query: 299 ECLDAVINRYRKEQI 313
L+ +++ Y I
Sbjct: 123 TSLNKLVDYYTHNSI 137
Score = 48.4 bits (110), Expect = 9e-04
Identities = 24/88 (27%), Positives = 45/88 (51%), Gaps = 3/88 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVC-GDYY 124
WY R ++++ L G++++R S PG + +S + HF++ G YY
Sbjct: 58 WYKENTSRQSAQDELMC-QPIGAFIIRGSQSSPGDFSISVRHENDVQHFKVMRDRQGRYY 116
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERL 152
+ F SL +LV +Y+H + + K+ R+
Sbjct: 117 LWSEMFTSLNKLVDYYTH-NSISKQSRV 143
>UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monosiga
ovata|Rep: Protein tyrosine kinase CSK - Monosiga ovata
Length = 468
Score = 64.1 bits (149), Expect = 2e-08
Identities = 42/159 (26%), Positives = 70/159 (44%), Gaps = 12/159 (7%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFS------ 234
++L F+KGDI + N D W+ +TG GMI VE +
Sbjct: 36 EDLPFKKGDILTIENPTEDPNWWLVRDKTGRTGMIPANYVELIGSDTKKTGTLPRDASGQ 95
Query: 235 -----WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV 289
WFH ++ A +L+ G FLVR S + PGDY+L +Q+ +R++ K
Sbjct: 96 LIPMPWFHGKISRELAESLLMPREDGLFLVRESAHFPGDYTLCVCFQDQVDHYRMQGKNG 155
Query: 290 RYLMGGRT-FECLDAVINRYRKEQIVEGHTLGQPLIAEG 327
+ + F L+ ++ Y K+ L +P++ +G
Sbjct: 156 KLTIDEEVYFSSLEELVQHYEKDADGLCTRLRKPVVKQG 194
Score = 47.6 bits (108), Expect = 0.002
Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
W+HG++ R +E L + G +LVRES PG Y L + ++H+R+ G I
Sbjct: 101 WFHGKISRELAESLLMPR-EDGLFLVRESAHFPGDYTLCVCFQDQVDHYRMQGKNGKLTI 159
Query: 126 GGR-QFDSLTELVGFYSHCSD 145
F SL ELV Y +D
Sbjct: 160 DEEVYFSSLEELVQHYEKDAD 180
>UniRef50_A7SCW1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 64.1 bits (149), Expect = 2e-08
Identities = 50/159 (31%), Positives = 69/159 (43%), Gaps = 10/159 (6%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
WYHG L R +E L G +LVR+S PG YVLS ++H+ I Y I
Sbjct: 9 WYHGVLKRVETEGIL-NGKPPGVWLVRDSTTIPGDYVLSVSESGKVSHYIINNKGTMYTI 67
Query: 126 GGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRV-VAILPYTKMPDTDELT 184
G + F L ++ FY K+ L N + + V L D ++L
Sbjct: 68 GDQTFPDLPSIIEFY-------KKHFLDTTTLKEHVPNSECNIKVKALYAFPGKDDEDLP 120
Query: 185 FQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDL 223
F+KGDI V + D W W G +GMI + V+ L
Sbjct: 121 FKKGDILTVISKEEDNW-WKARDSAGREGMIPKPYVQVL 158
Score = 52.8 bits (121), Expect = 4e-05
Identities = 26/76 (34%), Positives = 39/76 (51%)
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMG 294
W+H + E +L PG +LVR S PGDY L + ++ + I KG Y +G
Sbjct: 9 WYHGVLKRVETEGILNGKPPGVWLVRDSTTIPGDYVLSVSESGKVSHYIINNKGTMYTIG 68
Query: 295 GRTFECLDAVINRYRK 310
+TF L ++I Y+K
Sbjct: 69 DQTFPDLPSIIEFYKK 84
>UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1;
n=11; Metazoa|Rep: Tyrosine-protein kinase isoform SRK1
- Spongilla lacustris (Freshwater sponge)
Length = 505
Score = 64.1 bits (149), Expect = 2e-08
Identities = 40/136 (29%), Positives = 72/136 (52%), Gaps = 9/136 (6%)
Query: 181 DELTFQKGDIFFV-HNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPN 239
D+L+F+KGD+ ++ D GD W + G++G I V + S+D WF
Sbjct: 71 DDLSFKKGDLMYIISTDEGDWWFARSKDTAGKEGYIPSNYVAEYK-SLDAE---EWFLGK 126
Query: 240 CTKSEAVDMLVKA--GPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK--KGVRYLMGG 295
+ EA ML ++ GSFL+R S+ +PGD+SL ++++ +R+ + G ++
Sbjct: 127 IKRVEAEKMLNQSFNQVGSFLIRDSETTPGDFSLSVKDQDRVRHYRVRRLEDGSLFVTRR 186
Query: 296 RTFECLDAVINRYRKE 311
TF+ L +++ Y+ E
Sbjct: 187 STFQILHELVDHYKIE 202
Score = 46.4 bits (105), Expect = 0.004
Identities = 26/79 (32%), Positives = 44/79 (55%), Gaps = 3/79 (3%)
Query: 65 EWYHGRLDRYTSEERLWAASKQ-GSYLVRESDRKPGSYVLSYLGRTGINHFRITAV-CGD 122
EW+ G++ R +E+ L + Q GS+L+R+S+ PG + LS + + H+R+ + G
Sbjct: 121 EWFLGKIKRVEAEKMLNQSFNQVGSFLIRDSETTPGDFSLSVKDQDRVRHYRVRRLEDGS 180
Query: 123 YYIGGRQ-FDSLTELVGFY 140
++ R F L ELV Y
Sbjct: 181 LFVTRRSTFQILHELVDHY 199
>UniRef50_Q4SAX0 Cluster: Chromosome 3 SCAF14679, whole genome
shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 3
SCAF14679, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 283
Score = 63.7 bits (148), Expect = 2e-08
Identities = 37/134 (27%), Positives = 68/134 (50%), Gaps = 14/134 (10%)
Query: 182 ELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNCT 241
EL+F+KGDI + + D W A G++G + + +E P WF N +
Sbjct: 16 ELSFRKGDILKILSPEDD---WFKAEMNGQEGYVPQNYIEIQTPR--------WFQENAS 64
Query: 242 KSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGGRTFE 299
+S A ++L G G F++R +SPG++S+ + +Q F++ + +G +Y + F
Sbjct: 65 RSAAEELLRHKGVGEFVIRGCQSSPGEFSISVRHESDVQHFKVMRDSRG-QYFLWSEKFT 123
Query: 300 CLDAVINRYRKEQI 313
L+ +++ YR I
Sbjct: 124 SLNKLVDFYRTSSI 137
Score = 42.7 bits (96), Expect = 0.044
Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVC-GDYY 124
W+ R +EE L G +++R PG + +S + + HF++ G Y+
Sbjct: 58 WFQENASRSAAEELL-RHKGVGEFVIRGCQSSPGEFSISVRHESDVQHFKVMRDSRGQYF 116
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRE 150
+ +F SL +LV FY S RE
Sbjct: 117 LWSEKFTSLNKLVDFYRTSSISKTRE 142
>UniRef50_Q5A506 Cluster: Putative uncharacterized protein BUD2;
n=1; Candida albicans|Rep: Putative uncharacterized
protein BUD2 - Candida albicans (Yeast)
Length = 1237
Score = 63.7 bits (148), Expect = 2e-08
Identities = 31/91 (34%), Positives = 51/91 (56%), Gaps = 1/91 (1%)
Query: 775 PNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVE 834
P ++ +S FIFLR CPA++ P+ + L + QR+L ++AK L N AN E
Sbjct: 816 PEDKVTSLNCLSAFIFLRFFCPAILNPKLFYLAKNHQTGSTQRTLTLIAKILLNFANRQE 875
Query: 835 FGA-KEPYMEVVNPFILKNKERMVVFLDQLS 864
F KEP++ +N F+ K+ + + D+L+
Sbjct: 876 FSPHKEPHLVRMNVFLRKHTPEIYDYFDKLT 906
>UniRef50_UPI00004997E1 Cluster: hypothetical protein 291.t00003;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
protein 291.t00003 - Entamoeba histolytica HM-1:IMSS
Length = 497
Score = 63.3 bits (147), Expect = 3e-08
Identities = 57/222 (25%), Positives = 99/222 (44%), Gaps = 9/222 (4%)
Query: 644 SVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAI 703
S+ + E G+ + E E++ + + L R S AT +L MR L+ +
Sbjct: 69 SIRDLLEESGQIYRILSEELQYEISNTSEEQFLLRSNSGATHLLSSVMRRDLTSLLEKHM 128
Query: 704 SETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTS-PEACPKPVRYL 762
+ IQ + + T +++ +DS DD + L L + S F S P+ ++Y+
Sbjct: 129 NPIIQSV--NHITDQIS---LDSKDDNYTKSITTLSELLHLHCSRFLSLGNDFPQGIKYI 183
Query: 763 CGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMV 822
L+ A K+P+ R ++ IF RLI PALV P + P +A++ L+++
Sbjct: 184 LATLRNAVSEKFPDSAI---RSIAIIIFHRLITPALVSPANYNSCLIEPTENAKKILVIL 240
Query: 823 AKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLS 864
K Q+ E P + N +++ E M FLD +S
Sbjct: 241 TKIYQSFIPQGETPLTNPQLIPFNTYVVSMYESMNKFLDSIS 282
>UniRef50_UPI00015A79D6 Cluster: hypothetical protein LOC550452;
n=1; Danio rerio|Rep: hypothetical protein LOC550452 -
Danio rerio
Length = 250
Score = 62.5 bits (145), Expect = 5e-08
Identities = 38/134 (28%), Positives = 65/134 (48%), Gaps = 12/134 (8%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNC 240
DEL+F+KGD + D W A G +G + + V+ PS WF +
Sbjct: 15 DELSFRKGDTLKILGSQDD---WFKAELHGHEGYVPKNYVDRQIPS--------WFKESA 63
Query: 241 TKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK-KGVRYLMGGRTFE 299
++ A + L+ G+FL+R S +SPGD+S+ + +Q F++ K K Y + F
Sbjct: 64 SRGSAEETLMSREVGAFLIRGSQSSPGDFSISVRHDYDVQHFKVMKDKSGHYYLWTEKFT 123
Query: 300 CLDAVINRYRKEQI 313
L+ +++ Y+ I
Sbjct: 124 SLNKLVDFYKTTSI 137
Score = 46.8 bits (106), Expect = 0.003
Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDYY 124
W+ R ++EE L + + G++L+R S PG + +S + HF++ G YY
Sbjct: 58 WFKESASRGSAEETLMSR-EVGAFLIRGSQSSPGDFSISVRHDYDVQHFKVMKDKSGHYY 116
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRE 150
+ +F SL +LV FY S ++E
Sbjct: 117 LWTEKFTSLNKLVDFYKTTSISKQKE 142
>UniRef50_Q567F1 Cluster: Zgc:112091; n=2; Euteleostomi|Rep:
Zgc:112091 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 284
Score = 62.5 bits (145), Expect = 5e-08
Identities = 38/134 (28%), Positives = 65/134 (48%), Gaps = 12/134 (8%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNC 240
DEL+F+KGD + D W A G +G + + V+ PS WF +
Sbjct: 15 DELSFRKGDTLKILGSQDD---WFKAELHGHEGYVPKNYVDRQIPS--------WFKESA 63
Query: 241 TKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK-KGVRYLMGGRTFE 299
++ A + L+ G+FL+R S +SPGD+S+ + +Q F++ K K Y + F
Sbjct: 64 SRGSAEETLMSREVGAFLIRGSQSSPGDFSISVRHDYDVQHFKVMKDKSGHYYLWTEKFT 123
Query: 300 CLDAVINRYRKEQI 313
L+ +++ Y+ I
Sbjct: 124 SLNKLVDFYKTTSI 137
Score = 46.8 bits (106), Expect = 0.003
Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDYY 124
W+ R ++EE L + + G++L+R S PG + +S + HF++ G YY
Sbjct: 58 WFKESASRGSAEETLMSR-EVGAFLIRGSQSSPGDFSISVRHDYDVQHFKVMKDKSGHYY 116
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRE 150
+ +F SL +LV FY S ++E
Sbjct: 117 LWTEKFTSLNKLVDFYKTTSISKQKE 142
>UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa
group|Rep: Src family kinase - Asterina miniata (Bat
star) (Patiria miniata)
Length = 563
Score = 62.5 bits (145), Expect = 5e-08
Identities = 43/140 (30%), Positives = 66/140 (47%), Gaps = 13/140 (9%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNC 240
D+LTF+KG+I + N W T+ T +G + R +E P+ D WF
Sbjct: 133 DDLTFRKGEILIITNKTDPNWWLATSMLTKREGYVPRNYIE---PA-DVLQAEDWFFEKM 188
Query: 241 TKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVR-------Y 291
T+ EA L AG G+FL+R S+ SPG YSL ++ + F ++ +R Y
Sbjct: 189 TRKEAEKQLQLAGNSRGTFLIRGSETSPGAYSLSVLDHDDARGFNVKHYRIRTLDNDGYY 248
Query: 292 LMGGRTFECLDAVINRYRKE 311
+ TF L ++N Y +
Sbjct: 249 ISTRITFHTLHDLVNHYTSQ 268
Score = 48.0 bits (109), Expect = 0.001
Identities = 29/89 (32%), Positives = 50/89 (56%), Gaps = 8/89 (8%)
Query: 65 EWYHGRLDRYTSEERLW-AASKQGSYLVRESDRKPGSYVLSYLGRT-----GINHFRITA 118
+W+ ++ R +E++L A + +G++L+R S+ PG+Y LS L + H+RI
Sbjct: 182 DWFFEKMTRKEAEKQLQLAGNSRGTFLIRGSETSPGAYSLSVLDHDDARGFNVKHYRIRT 241
Query: 119 VCGD-YYIGGR-QFDSLTELVGFYSHCSD 145
+ D YYI R F +L +LV Y+ +D
Sbjct: 242 LDNDGYYISTRITFHTLHDLVNHYTSQAD 270
>UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-protein
kinase; n=38; Euteleostomi|Rep: Megakaryocyte-associated
tyrosine-protein kinase - Homo sapiens (Human)
Length = 507
Score = 62.5 bits (145), Expect = 5e-08
Identities = 39/139 (28%), Positives = 63/139 (45%), Gaps = 4/139 (2%)
Query: 178 PDTDELTFQKGDIFFVHNDMGD-GWLWVTAHRTGEQGMIFRELVEDLDP-SIDPN-TVFS 234
P EL F+KGD+ + + W V H +G++G++ + + + S DP ++
Sbjct: 62 PKPGELAFRKGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALREREALSADPKLSLMP 121
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMG 294
WFH + EAV L G FLVR S PGDY L + +R+ + +
Sbjct: 122 WFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTID 181
Query: 295 GRTFEC-LDAVINRYRKEQ 312
F C L ++ Y K++
Sbjct: 182 EAVFFCNLMDMVEHYSKDK 200
Score = 44.8 bits (101), Expect = 0.011
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 5/92 (5%)
Query: 54 ERQAVLAPPETE---WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTG 110
ER+A+ A P+ W+HG++ + ++L + G +LVRES R PG YVL
Sbjct: 107 EREALSADPKLSLMPWFHGKISGQEAVQQL-QPPEDGLFLVRESARHPGDYVLCVSFGRD 165
Query: 111 INHFRITAVCGDYYIGGRQ-FDSLTELVGFYS 141
+ H+R+ G I F +L ++V YS
Sbjct: 166 VIHYRVLHRDGHLTIDEAVFFCNLMDMVEHYS 197
>UniRef50_O15815 Cluster: RasGTPase-activating protein; n=3;
Dictyostelium discoideum|Rep: RasGTPase-activating
protein - Dictyostelium discoideum (Slime mold)
Length = 822
Score = 62.1 bits (144), Expect = 7e-08
Identities = 38/134 (28%), Positives = 68/134 (50%), Gaps = 1/134 (0%)
Query: 737 LLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRT-RVVSGFIFLRLIC 795
L+ I +Q I +S P +R++C + + A + T +V+ FI+ R I
Sbjct: 350 LISICEQFLDGIISSLNRLPYGIRWICKQIYQIAEKNFTKSTQDETLKVIGYFIYYRFIQ 409
Query: 796 PALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKER 855
A+V P + LV R P A+++L+ V+K LQ L N +FG+ E + +N +I +
Sbjct: 410 VAMVSPEEYDLVGREIHPTARKNLINVSKVLQALFNFAQFGSSEKHFIPLNGWITSHMGD 469
Query: 856 MVVFLDQLSNVPDP 869
+ +L ++ V +P
Sbjct: 470 IKNYLQEIIEVGEP 483
>UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-receptor
type 11; n=73; Bilateria|Rep: Tyrosine-protein
phosphatase non-receptor type 11 - Homo sapiens (Human)
Length = 597
Score = 61.3 bits (142), Expect = 1e-07
Identities = 31/76 (40%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFHPN T EA ++L+ G GSFL RPS ++PGD++L N + +I+ G Y L
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDL 65
Query: 293 MGGRTFECLDAVINRY 308
GG F L ++ Y
Sbjct: 66 YGGEKFATLAELVQYY 81
Score = 55.2 bits (127), Expect = 8e-06
Identities = 34/91 (37%), Positives = 45/91 (49%), Gaps = 11/91 (12%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYL----------GRTG 110
P W+HG L +E+ L K GS+LVRES PG +VLS G++
Sbjct: 107 PTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSK 166
Query: 111 INHFRITAVCGDYYI-GGRQFDSLTELVGFY 140
+ H I Y + GG +FDSLT+LV Y
Sbjct: 167 VTHVMIRCQELKYDVGGGERFDSLTDLVEHY 197
Score = 52.4 bits (120), Expect = 5e-05
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 3/87 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H + +E L GS+L R S PG + LS + H +I GDYY
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNT-GDYYD 64
Query: 125 -IGGRQFDSLTELVGFYSHCSDLLKRE 150
GG +F +L ELV +Y LK +
Sbjct: 65 LYGGEKFATLAELVQYYMEHHGQLKEK 91
Score = 46.0 bits (104), Expect = 0.005
Identities = 42/135 (31%), Positives = 62/135 (45%), Gaps = 20/135 (14%)
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK 286
DP T WFH + + EA +L + G GSFLVR S + PGD+ L + K
Sbjct: 106 DP-TSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGK 164
Query: 287 KGVRYLM-----------GGRTFECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQS 335
V ++M GG F+ L ++ Y+K +VE TLG L ++ +
Sbjct: 165 SKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVE--TLGTVL-----QLKQPLN 217
Query: 336 TTGAAAEKIYATLRE 350
TT A +I + +RE
Sbjct: 218 TTRINAAEIESRVRE 232
>UniRef50_Q6FQA1 Cluster: Candida glabrata strain CBS138 chromosome I
complete sequence; n=1; Candida glabrata|Rep: Candida
glabrata strain CBS138 chromosome I complete sequence -
Candida glabrata (Yeast) (Torulopsis glabrata)
Length = 3036
Score = 60.5 bits (140), Expect = 2e-07
Identities = 54/206 (26%), Positives = 94/206 (45%), Gaps = 11/206 (5%)
Query: 661 ELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELN 720
+L AE+ + + R S+AT L R +L + T+ LI +++ E+
Sbjct: 1677 QLIDAEIEQSTRSTDILRRNSVATRALSMLARLKGNKYLIKTLQPTLLDLIRNQEVFEVE 1736
Query: 721 PTKMDSPD---DACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNE 777
+K + D +++ ILD IT S+ P + Y+C + + K+P+
Sbjct: 1737 KSKPPGENYERDVALFKKYMNKILDSITDSL----SYMPPELFYICQGIYQNVKEKFPDY 1792
Query: 778 RFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGA 837
V V +FLR ICPALV P + LV ++S + +AK +QN+AN E
Sbjct: 1793 ALV---AVGSCMFLRFICPALVSPESENLVNTISIKE-KKSFISLAKVIQNIANGSENYV 1848
Query: 838 KEPYMEVVNPFILKNKERMVVFLDQL 863
K ++ F + K+++ FL ++
Sbjct: 1849 KWESLKDECQFFDECKKKIFDFLAEV 1874
>UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3;
Gallus gallus|Rep: Putative uncharacterized protein -
Gallus gallus (Chicken)
Length = 431
Score = 60.1 bits (139), Expect = 3e-07
Identities = 30/80 (37%), Positives = 46/80 (57%), Gaps = 2/80 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFHPN + EA +L+ G GSFL RPS ++PGD++L N+++ +I+ G Y L
Sbjct: 4 WFHPNISGIEAEKLLLTRGVHGSFLARPSKSNPGDFTLSVRRNDEVTHIKIQNTGDYYDL 63
Query: 293 MGGRTFECLDAVINRYRKEQ 312
GG F ++ Y ++Q
Sbjct: 64 YGGEKFARKPELVQYYTEQQ 83
Score = 51.6 bits (118), Expect = 1e-04
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H + +E+ L GS+L R S PG + LS + H +I GDYY
Sbjct: 4 WFHPNISGIEAEKLLLTRGVHGSFLARPSKSNPGDFTLSVRRNDEVTHIKIQNT-GDYYD 62
Query: 125 -IGGRQFDSLTELVGFYSHCSDLLKRE 150
GG +F ELV +Y+ LL+ +
Sbjct: 63 LYGGEKFARKPELVQYYTEQQGLLREK 89
Score = 50.0 bits (114), Expect = 3e-04
Identities = 23/46 (50%), Positives = 27/46 (58%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYL 106
P WYHG L +E+ L K GS+LVRES KPG +VLS L
Sbjct: 105 PTSERWYHGHLTGKEAEKLLTEKGKPGSFLVRESQSKPGDFVLSVL 150
Score = 42.3 bits (95), Expect = 0.058
Identities = 22/45 (48%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSL 271
DP T W+H + T EA +L + G PGSFLVR S + PGD+ L
Sbjct: 104 DP-TSERWYHGHLTGKEAEKLLTEKGKPGSFLVRESQSKPGDFVL 147
>UniRef50_A7TEG6 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 3030
Score = 60.1 bits (139), Expect = 3e-07
Identities = 47/228 (20%), Positives = 94/228 (41%), Gaps = 5/228 (2%)
Query: 642 ATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQA 701
A+ + F + E+ ++ + + R + T+ L + R +L
Sbjct: 1656 ASGFMTLFENSSGVTTMVNEMLRDDIRKTSRPTNILRRNNCVTSALSIYTRKVGHEYLVK 1715
Query: 702 AISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRY 761
+S +LI+ + ++ D+ + N +D++ SI S P
Sbjct: 1716 TLSTVFMELIELDEHFDIERIG-DNEVEIERNIRLFKKYMDKVITSIEKSITYFPPDFFS 1774
Query: 762 LCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLM 821
+C + + K+P + V F FLR +CPA+V P + ++ ++SL+
Sbjct: 1775 ICQNIHTTTLEKFPEHAII---AVGSFFFLRFLCPAVVSPESENIIPIVELKF-RKSLIA 1830
Query: 822 VAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDP 869
+AK +Q+LAN ++ K +E F+ R+ FL ++S + P
Sbjct: 1831 LAKVIQSLANGIDNRIKWQLLERETEFLKNCSIRIFAFLIEISKLDRP 1878
>UniRef50_Q9UN19 Cluster: Dual adapter for phosphotyrosine and
3-phosphotyrosine and 3- phosphoinositide; n=25;
Euteleostomi|Rep: Dual adapter for phosphotyrosine and
3-phosphotyrosine and 3- phosphoinositide - Homo sapiens
(Human)
Length = 280
Score = 60.1 bits (139), Expect = 3e-07
Identities = 57/234 (24%), Positives = 100/234 (42%), Gaps = 17/234 (7%)
Query: 235 WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLM 293
W+H N T+ A +L+ G GS+L+R S+ + G YSL + ++ F +E G +
Sbjct: 35 WYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKF 94
Query: 294 GGRTFECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQSTTGAAAEKIYATLRECRD 353
G F L + + + ++ G G ++ + + + + +++ ++ R
Sbjct: 95 GFNEFSSLKDFVKHFANQPLI-GSETGTLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRT 153
Query: 354 QIGLKKTK---GIKHYGYLNKKSDKGAKKWKPLYCVLLQEGTDTHLYFYDSPKRTKPKGL 410
+ L T G K GYL K+ K WK + L + L ++ +P +
Sbjct: 154 EDDLVPTAPSLGTKE-GYLTKQGGL-VKTWKTRWFTLHR----NELKYFKDQMSPEPIRI 207
Query: 411 IDLSCAYLYQVHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALR 464
+DL+ Q S E+ CF LV P + +L A T E WI+ LR
Sbjct: 208 LDLTECSAVQFDYS-QERVNCFCLV---FPFRT--FYLCAKTGVEADEWIKILR 255
Score = 55.6 bits (128), Expect = 6e-06
Identities = 25/77 (32%), Positives = 40/77 (51%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
WYHG L R+ +E L + GSYL+R+S+ G Y LS + + HF + +
Sbjct: 35 WYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKF 94
Query: 126 GGRQFDSLTELVGFYSH 142
G +F SL + V +++
Sbjct: 95 GFNEFSSLKDFVKHFAN 111
>UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew;
n=15; Eumetazoa|Rep: Tyrosine-protein phosphatase
corkscrew - Drosophila melanogaster (Fruit fly)
Length = 845
Score = 60.1 bits (139), Expect = 3e-07
Identities = 33/85 (38%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
Query: 58 VLAPPETE-WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI 116
+ A P TE W+HG L +E+ + K GS+LVRES KPG +VLS + H I
Sbjct: 102 ICAEPTTERWFHGNLSGKEAEKLILERGKNGSFLVRESQSKPGDFVLSVRTDDKVTHVMI 161
Query: 117 TAVCGDYYI-GGRQFDSLTELVGFY 140
Y + GG F +L+EL+ Y
Sbjct: 162 RWQDKKYDVGGGESFGTLSELIDHY 186
Score = 56.0 bits (129), Expect = 4e-06
Identities = 29/87 (33%), Positives = 49/87 (56%), Gaps = 2/87 (2%)
Query: 231 TVFSWFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV 289
T WFH N + EA ++++ G GSFLVR S + PGD+ L ++++ I +
Sbjct: 107 TTERWFHGNLSGKEAEKLILERGKNGSFLVRESQSKPGDFVLSVRTDDKVTHVMIRWQDK 166
Query: 290 RY-LMGGRTFECLDAVINRYRKEQIVE 315
+Y + GG +F L +I+ Y++ +VE
Sbjct: 167 KYDVGGGESFGTLSELIDHYKRNPMVE 193
Score = 54.4 bits (125), Expect = 1e-05
Identities = 39/119 (32%), Positives = 58/119 (48%), Gaps = 9/119 (7%)
Query: 235 WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFHP + EA +L + G GSFL R S ++PG ++L N++ +I+ G + L
Sbjct: 6 WFHPTISGIEAEKLLQEQGFDGSFLARLSSSNPGAFTLSVRRGNEVTHIKIQNNGDFFDL 65
Query: 293 MGGRTFECLDAVINRYR-----KEQIVEGHTLGQPLIAEGHTIEP--QQSTTGAAAEKI 344
GG F L ++ Y KE+ + L QPLI T E + +G AEK+
Sbjct: 66 YGGEKFATLPELVQYYMENGELKEKNGQAIELKQPLICAEPTTERWFHGNLSGKEAEKL 124
Score = 46.8 bits (106), Expect = 0.003
Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H + +E+ L GS+L R S PG++ LS + H +I GD++
Sbjct: 6 WFHPTISGIEAEKLLQEQGFDGSFLARLSSSNPGAFTLSVRRGNEVTHIKIQN-NGDFFD 64
Query: 125 -IGGRQFDSLTELVGFYSHCSDLLKR 149
GG +F +L ELV +Y +L ++
Sbjct: 65 LYGGEKFATLPELVQYYMENGELKEK 90
>UniRef50_O75791 Cluster: GRB2-related adapter protein 2; n=22;
Amniota|Rep: GRB2-related adapter protein 2 - Homo
sapiens (Human)
Length = 330
Score = 59.3 bits (137), Expect = 5e-07
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 14/135 (10%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNC 240
DEL+F GD+ + ++ + W A ++G + + ++ P WFH
Sbjct: 15 DELSFHTGDVLKILSNQEE---WFKAELGSQEGYVPKNFIDIQFPK--------WFHEGL 63
Query: 241 TKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGGRTF 298
++ +A ++L+ G F++R S +SPGD+S+ + +Q F++ + KG Y + F
Sbjct: 64 SRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKG-NYFLWTEKF 122
Query: 299 ECLDAVINRYRKEQI 313
L+ +++ YR I
Sbjct: 123 PSLNKLVDYYRTNSI 137
Score = 46.8 bits (106), Expect = 0.003
Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDY 123
+W+H L R+ +E L + G +++R S PG + +S + HF++ G+Y
Sbjct: 57 KWFHEGLSRHQAENLLMG-KEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115
Query: 124 YIGGRQFDSLTELVGFY 140
++ +F SL +LV +Y
Sbjct: 116 FLWTEKFPSLNKLVDYY 132
>UniRef50_Q9XYM0 Cluster: Adapter molecule Crk; n=7;
Endopterygota|Rep: Adapter molecule Crk - Drosophila
melanogaster (Fruit fly)
Length = 271
Score = 59.3 bits (137), Expect = 5e-07
Identities = 45/172 (26%), Positives = 79/172 (45%), Gaps = 15/172 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGD--- 122
WY G + R + E L ++G +LVR+S+ G YVL T ++++ I V
Sbjct: 12 WYFGPMSRQDATEVLMNERERGVFLVRDSNSIAGDYVLCVREDTKVSNYIINKVQQQDQI 71
Query: 123 -YYIGGRQFDSLTELVGFYS-HCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDT 180
Y IG + FD+L +L+ FY+ H D +R ++V+ + D
Sbjct: 72 VYRIGDQSFDNLPKLLTFYTLHYLDTTPLKR--------PACRRVEKVIGKFDFVG-SDQ 122
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTV 232
D+L FQ+G++ + D W W + +G+ G I ++ D +D + +
Sbjct: 123 DDLPFQRGEVLTIVRKDEDQW-WTARNSSGKIGQIPVPYIQQYDDYMDEDAI 173
>UniRef50_UPI0000F2C9B7 Cluster: PREDICTED: similar to FLJ00412
protein; n=1; Monodelphis domestica|Rep: PREDICTED:
similar to FLJ00412 protein - Monodelphis domestica
Length = 752
Score = 58.8 bits (136), Expect = 6e-07
Identities = 58/202 (28%), Positives = 84/202 (41%), Gaps = 20/202 (9%)
Query: 418 LYQVHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCK 477
++ +H SL + +CFQ+ P S + +A E WIE LR P Q + K
Sbjct: 148 VWPLHPSLLGEPYCFQVT---WP--SGSRCFSCGSAVERDRWIEDLRQSLQPHQESQERK 202
Query: 478 VGRVSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDPHWXXXXXXXX 537
WL V A LP + + + L A +ART RP P W
Sbjct: 203 E------TWLSVWIHEAKELPQGSSQGLRVELWLDGALLARTAARPGPH-FWAERFHFEA 255
Query: 538 MPPDVTSLTITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPIGEWGSLRL 597
+PP L++ + G R + LT EL + G +E W+PL G P +LR
Sbjct: 256 LPP-AHHLSLRLCQ-GDRNLGNVSLALT-ELGQMGGG--LERWFPLEGGPP---GAALRA 307
Query: 598 RIRYMQELVMPREEYNPLRQLL 619
R+R ++P E Y L + L
Sbjct: 308 RVRARCLRILPTERYKELAEFL 329
>UniRef50_Q4T1V0 Cluster: Chromosome undetermined SCAF10467, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF10467, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 767
Score = 58.4 bits (135), Expect = 8e-07
Identities = 31/89 (34%), Positives = 54/89 (60%), Gaps = 2/89 (2%)
Query: 780 VRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANL-VEFG-A 837
V+ +SGF FLR PA++ P+ + L ++ R+LL++AK LQ++ NL ++ G
Sbjct: 430 VKYLAISGFFFLRFFAPAILTPKLFQLREQHADTRTSRTLLLLAKALQSVGNLGLQLGQG 489
Query: 838 KEPYMEVVNPFILKNKERMVVFLDQLSNV 866
KE +ME ++P I + + FLD+L ++
Sbjct: 490 KEQWMEPLHPIIRLSVASVKEFLDRLIDI 518
Score = 55.6 bits (128), Expect = 6e-06
Identities = 40/149 (26%), Positives = 72/149 (48%), Gaps = 14/149 (9%)
Query: 590 GEWGSLRLRIRYMQELVMPREEYNPLRQLLLEPGI--------PAVKALADLCRTD-RQP 640
G G+LRL++R +++ ++P Y PL LL+E + A+ L ++ + RQ
Sbjct: 182 GNLGALRLKVRLIEDHILPSVYYQPLIHLLVESVVAPAEVEDSSALTMLEEVTTVESRQD 241
Query: 641 LATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRA----HC- 695
+A +++ + L EV D TLFR SLA+ +++FM+ H
Sbjct: 242 VAMTLVKIYLGQRLVVPFLDYLNTREVQHTTDPNTLFRSNSLASKAMEQFMKVSRGMHVG 301
Query: 696 KPFLQAAISETIQKLIDSKQTAELNPTKM 724
P+L + I ++ D ++ EL+P K+
Sbjct: 302 MPYLHEVLKPIINRIFDERKYIELDPCKI 330
>UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome
shotgun sequence; n=2; Euteleostei|Rep: Chromosome 13
SCAF14566, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1249
Score = 58.4 bits (135), Expect = 8e-07
Identities = 31/113 (27%), Positives = 59/113 (52%), Gaps = 2/113 (1%)
Query: 216 FRELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFH 274
F + D P P+ WF+ + ++ +A D L++ G+FL+R + P +++ F
Sbjct: 613 FELRLTDAVPQPSPHLNEGWFYSDLSRGQAEDYLMRIPRDGAFLIRQREGEPDSFAITFK 672
Query: 275 INNQIQRFRIEKKGVRYLMGGRT-FECLDAVINRYRKEQIVEGHTLGQPLIAE 326
+ +++ RI+K+G RYL+G T FE L +++ +R + L P+ E
Sbjct: 673 GDGKVKHCRIQKEGTRYLLGTTTYFESLVELVSYFRNRPLYRKIKLRYPVTPE 725
Score = 48.0 bits (109), Expect = 0.001
Identities = 22/76 (28%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
W++ L R +E+ L + G++L+R+ + +P S+ +++ G + H RI Y +
Sbjct: 632 WFYSDLSRGQAEDYLMRIPRDGAFLIRQREGEPDSFAITFKGDGKVKHCRIQKEGTRYLL 691
Query: 126 G-GRQFDSLTELVGFY 140
G F+SL ELV ++
Sbjct: 692 GTTTYFESLVELVSYF 707
Score = 35.9 bits (79), Expect = 5.1
Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 5/64 (7%)
Query: 255 GSFLVRPSDNSPGDYSLFFHINNQIQ--RFRIEKKGVR---YLMGGRTFECLDAVINRYR 309
G+FLVRPSD Y+L F N ++Q R R+ +G R +L F L ++I YR
Sbjct: 545 GTFLVRPSDRVVLSYTLSFWRNGRVQHCRVRVGNQGGRPYYFLTANLHFPSLISLIQHYR 604
Query: 310 KEQI 313
+ +
Sbjct: 605 ENPL 608
>UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to
Tyrosine-protein kinase Src64B (Dsrc64) isoform 2; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to
Tyrosine-protein kinase Src64B (Dsrc64) isoform 2 -
Tribolium castaneum
Length = 473
Score = 58.0 bits (134), Expect = 1e-06
Identities = 46/153 (30%), Positives = 76/153 (49%), Gaps = 13/153 (8%)
Query: 165 KKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLD 224
K RVV L + D+ +++F+KGD V +D WL V T QG I V +
Sbjct: 69 KGRVVVALYNYEARDSSDVSFKKGDRMEVIDDSEGDWLNVIHLITKVQGYIPGNFVA-AE 127
Query: 225 PSIDPNTVFSWFHPNCTKSEAVDMLV-KAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRF 282
S++ WF N ++ EA +L+ + P G+FLVRPS+++P YSL +I+ +
Sbjct: 128 LSVESE---DWFFENVSRKEAEKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEEIREY 184
Query: 283 RIEKKGVR-------YLMGGRTFECLDAVINRY 308
++ ++ Y+ +TF L ++N Y
Sbjct: 185 HVKHYKIKPLDNGGFYISTNKTFLTLVELVNAY 217
>UniRef50_UPI00004989A6 Cluster: Ras GTPase activating protein; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: Ras GTPase
activating protein - Entamoeba histolytica HM-1:IMSS
Length = 411
Score = 58.0 bits (134), Expect = 1e-06
Identities = 46/190 (24%), Positives = 91/190 (47%), Gaps = 5/190 (2%)
Query: 676 LFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACNNAE 735
LFR T V R + L I+ ++++ + E++ +K+ + A N E
Sbjct: 49 LFRSNKGVTYVTAAMCRRLTEDLLVEYINPLLEEINSYTEPLEIDNSKVGD-EKAKKNIE 107
Query: 736 FLLMILDQITLSIFT-SPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLI 794
++ ++++ ++ T S + CP+ + Y+ ++ A ++ +E ++ +V F+FLRLI
Sbjct: 108 IVVNYVNKLFDTVTTLSKKFCPE-LTYIFTKVRLAVKERYGDEESLK--IVGAFVFLRLI 164
Query: 795 CPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKE 854
P L+ P ++ P P + RSL++V K Q+ N +E YM + + L
Sbjct: 165 NPVLLTPLKFSSKLTKPSPSSLRSLIIVTKITQSCVNQSSTPFQEKYMLPITDYALGKYS 224
Query: 855 RMVVFLDQLS 864
+ LD +S
Sbjct: 225 FVTNLLDSVS 234
>UniRef50_UPI0000660CF8 Cluster: Crk-like protein.; n=3;
Euteleostomi|Rep: Crk-like protein. - Takifugu rubripes
Length = 314
Score = 58.0 bits (134), Expect = 1e-06
Identities = 46/167 (27%), Positives = 72/167 (43%), Gaps = 11/167 (6%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGD-YY 124
WY G + R+ ++ RL K G +LVR+S G YVLS + ++H+ I ++ +
Sbjct: 14 WYFGPVSRHEAQNRL-QGQKHGIFLVRDSSTCHGDYVLSVSENSKVSHYIINSLPNKRFK 72
Query: 125 IGGRQFDSLTELVGFYS-HCSDLL-------KRERLXXXXXXXXXXNDKKRVVAILPYTK 176
IG R+F+ L L+ FY H D + D V L
Sbjct: 73 IGDREFEHLPALLEFYKYHYLDTTTLIEPASRYPSTLSCPVQPAGPEDNLEYVRTLYDFT 132
Query: 177 MPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDL 223
D ++L F+KG++ + + W W ++ G GMI VE L
Sbjct: 133 GSDAEDLPFKKGEVLVILEKPEEQW-WSARNKDGRVGMIPVPYVEKL 178
Score = 41.5 bits (93), Expect = 0.10
Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 2/90 (2%)
Query: 234 SWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK-KGVRYL 292
+W+ ++ EA + L G FLVR S GDY L N+++ + I R+
Sbjct: 13 AWYFGPVSRHEAQNRLQGQKHGIFLVRDSSTCHGDYVLSVSENSKVSHYIINSLPNKRFK 72
Query: 293 MGGRTFECLDAVINRYRKEQIVEGHTLGQP 322
+G R FE L A++ Y K ++ TL +P
Sbjct: 73 IGDREFEHLPALLEFY-KYHYLDTTTLIEP 101
>UniRef50_Q4RNX3 Cluster: Chromosome 10 SCAF15009, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 10 SCAF15009, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 466
Score = 58.0 bits (134), Expect = 1e-06
Identities = 45/152 (29%), Positives = 71/152 (46%), Gaps = 14/152 (9%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
VVAI Y D D L F+KGD + N W + TG++G I + ++
Sbjct: 55 VVAIYSYNPKHDGD-LGFEKGDKLKIINKDDSEWYLAESLTTGQRGYIPYNFI-----AM 108
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSL----FFHINNQIQR 281
+WF N +++EA L+ G GSFLVR S+ +PG YSL F + + ++
Sbjct: 109 STMETEAWFFKNISRNEATRRLMAPGNTQGSFLVRESETTPGSYSLSMRDFDNNGDGVKH 168
Query: 282 FRIEK--KGVRYLMGGRTFECLDAVINRYRKE 311
+RI G Y+ +F L ++ Y ++
Sbjct: 169 YRIRNMDNGGFYITTKISFNSLKELVQHYSRD 200
Score = 55.6 bits (128), Expect = 6e-06
Identities = 39/91 (42%), Positives = 51/91 (56%), Gaps = 8/91 (8%)
Query: 63 ETE-WYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSYL----GRTGINHFRI 116
ETE W+ + R + RL A + QGS+LVRES+ PGSY LS G+ H+RI
Sbjct: 112 ETEAWFFKNISRNEATRRLMAPGNTQGSFLVRESETTPGSYSLSMRDFDNNGDGVKHYRI 171
Query: 117 TAV-CGDYYIGGR-QFDSLTELVGFYSHCSD 145
+ G +YI + F+SL ELV YS SD
Sbjct: 172 RNMDNGGFYITTKISFNSLKELVQHYSRDSD 202
>UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep:
ENSANGP00000020137 - Anopheles gambiae str. PEST
Length = 185
Score = 57.6 bits (133), Expect = 1e-06
Identities = 36/138 (26%), Positives = 70/138 (50%), Gaps = 8/138 (5%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDY 123
+WY+GR+ R E+L + +G++L+R S+ PG + LS G+ HF++ G +
Sbjct: 33 DWYYGRITR-ADAEKLLSNKHEGAFLIRISESSPGDFSLSVKCSDGVQHFKVLRDAQGKF 91
Query: 124 YIGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTDEL 183
++ +F+SL ELV ++ S + R + ++ V A+ + ++ EL
Sbjct: 92 FLWVVKFNSLNELVDYHRTAS--VSRSQ---DVKLRDMVPEEMLVQALYDFVAQ-ESGEL 145
Query: 184 TFQKGDIFFVHNDMGDGW 201
F++GD+ V + + W
Sbjct: 146 DFRRGDVITVTDRSDEHW 163
Score = 49.2 bits (112), Expect = 5e-04
Identities = 28/119 (23%), Positives = 60/119 (50%), Gaps = 9/119 (7%)
Query: 196 DMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPG 255
+M D W A G++G+I +E + W++ T+++A +L G
Sbjct: 3 NMEDDMNWYRAELDGKEGLIPSNYIEMKN--------HDWYYGRITRADAEKLLSNKHEG 54
Query: 256 SFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV-RYLMGGRTFECLDAVINRYRKEQI 313
+FL+R S++SPGD+SL ++ +Q F++ + ++ + F L+ +++ +R +
Sbjct: 55 AFLIRISESSPGDFSLSVKCSDGVQHFKVLRDAQGKFFLWVVKFNSLNELVDYHRTASV 113
>UniRef50_Q0PIN0 Cluster: Bam32; n=1; Branchiostoma belcheri
tsingtauense|Rep: Bam32 - Branchiostoma belcheri
tsingtauense
Length = 250
Score = 57.6 bits (133), Expect = 1e-06
Identities = 29/80 (36%), Positives = 43/80 (53%)
Query: 63 ETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGD 122
+ +WYHG L R+ +E L A ++ GSYL+R S + G Y LS + + HF+I
Sbjct: 11 QLDWYHGDLSRHMAEALLMANAEDGSYLLRSSATRVGEYSLSVKCKDSVKHFQIGWDGKQ 70
Query: 123 YYIGGRQFDSLTELVGFYSH 142
Y G F SL E V +++
Sbjct: 71 YQFGMGVFQSLQEFVEHFAN 90
Score = 45.2 bits (102), Expect = 0.008
Identities = 22/85 (25%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
Query: 235 WFHPNCTKSEAVDMLV-KAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLM 293
W+H + ++ A +L+ A GS+L+R S G+YSL + ++ F+I G +Y
Sbjct: 14 WYHGDLSRHMAEALLMANAEDGSYLLRSSATRVGEYSLSVKCKDSVKHFQIGWDGKQYQF 73
Query: 294 GGRTFECLDAVINRYRKEQIVEGHT 318
G F+ L + + + ++ G +
Sbjct: 74 GMGVFQSLQEFVEHFANQPLIGGES 98
>UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase
FER; n=109; root|Rep: Proto-oncogene tyrosine-protein
kinase FER - Homo sapiens (Human)
Length = 822
Score = 57.6 bits (133), Expect = 1e-06
Identities = 31/75 (41%), Positives = 40/75 (53%), Gaps = 3/75 (4%)
Query: 63 ETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGD 122
E +WYHG + R ++E L KQG +LVRES KPG YVLS HF I V
Sbjct: 457 EQDWYHGAIPRIEAQELL---KKQGDFLVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNM 513
Query: 123 YYIGGRQFDSLTELV 137
Y G F ++ +L+
Sbjct: 514 YRFEGTGFSNIPQLI 528
Score = 41.5 bits (93), Expect = 0.10
Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 3/81 (3%)
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMG 294
W+H + EA ++L K G FLVR S PG+Y L + + Q + F I+ Y
Sbjct: 460 WYHGAIPRIEAQELLKKQG--DFLVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFE 517
Query: 295 GRTFECLDAVI-NRYRKEQIV 314
G F + +I + Y +Q++
Sbjct: 518 GTGFSNIPQLIDHHYTTKQVI 538
>UniRef50_UPI0000E478D2 Cluster: PREDICTED: similar to SH2/SH3
adaptor Grb2; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to SH2/SH3 adaptor Grb2 -
Strongylocentrotus purpuratus
Length = 241
Score = 57.2 bits (132), Expect = 2e-06
Identities = 45/177 (25%), Positives = 81/177 (45%), Gaps = 17/177 (9%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKP--GSYVLSYLGRTGINHFRI-TAVCGD 122
WY G++ R +EE L + G++++R+S+ P G++ LS R + HF+I T + G
Sbjct: 62 WYVGKISRKVAEEYLMSMPSDGAFMIRDSESNPDSGNFSLSVKFRDQVQHFKILTDLAGK 121
Query: 123 YYIGGRQFDSLTELVGFY-----SHCSDLLKRERLXXXXX-------XXXXXNDKKRVVA 170
Y++ +F S+ +LV ++ S +++ E ++ + V
Sbjct: 122 YFLWVVKFTSINDLVDYHKDNSVSRTQEIVLNEPCVPIEDANQRPQPAMQQSRERLQQVK 181
Query: 171 ILPYTKMPDTDELTFQKGDIF-FVHNDMGDGWLWVTAHRTGEQGMIF-RELVEDLDP 225
L + D ELTF++ D+ D W TG + IF + V++LDP
Sbjct: 182 ALYNFESDDAQELTFKQNDVITLTGRPHADWWEGEIRAPTGTRRGIFPKNYVKELDP 238
Score = 42.3 bits (95), Expect = 0.058
Identities = 29/109 (26%), Positives = 57/109 (52%), Gaps = 12/109 (11%)
Query: 179 DTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHP 238
+ DEL F+KG++ V WL AH+ +QG++ ++ ++ S W+
Sbjct: 15 EQDELAFKKGEVLKVIKREDRHWL--LAHQGAKQGLVPENYLK-IEKS------HPWYVG 65
Query: 239 NCTKSEAVDMLVK-AGPGSFLVRPSDNSP--GDYSLFFHINNQIQRFRI 284
++ A + L+ G+F++R S+++P G++SL +Q+Q F+I
Sbjct: 66 KISRKVAEEYLMSMPSDGAFMIRDSESNPDSGNFSLSVKFRDQVQHFKI 114
>UniRef50_UPI00015A4B5A Cluster: protein tyrosine phosphatase,
non-receptor type 11 (Noonan syndrome 1); n=1; Danio
rerio|Rep: protein tyrosine phosphatase, non-receptor
type 11 (Noonan syndrome 1) - Danio rerio
Length = 564
Score = 57.2 bits (132), Expect = 2e-06
Identities = 26/62 (41%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
Query: 231 TVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV 289
+V+ WFHPN T EA ++L+ G GSFL RPS ++PGD++L N + +I+ G
Sbjct: 2 SVYRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGD 61
Query: 290 RY 291
Y
Sbjct: 62 YY 63
Score = 39.9 bits (89), Expect = 0.31
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
W+H + +E L GS+L R S PG + LS + H +I GDYY
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNT-GDYY 63
>UniRef50_P19174 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
phosphodiesterase gamma-1; n=65; Eumetazoa|Rep:
1-phosphatidylinositol-4,5-bisphosphate
phosphodiesterase gamma-1 - Homo sapiens (Human)
Length = 1290
Score = 57.2 bits (132), Expect = 2e-06
Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
EWYH L R +E L + G++LVR+ + +P SY +S+ I H R+
Sbjct: 667 EWYHASLTRAQAEHMLMRVPRDGAFLVRKRN-EPNSYAISFRAEGKIKHCRVQQEGQTVM 725
Query: 125 IGGRQFDSLTELVGFY 140
+G +FDSL +L+ +Y
Sbjct: 726 LGNSEFDSLVDLISYY 741
Score = 54.0 bits (124), Expect = 2e-05
Identities = 28/103 (27%), Positives = 53/103 (51%), Gaps = 2/103 (1%)
Query: 225 PSIDPNTVFSWFHPNCTKSEAVDMLVKA-GPGSFLVRPSDNSPGDYSLFFHINNQIQRFR 283
P + + W+H + T+++A ML++ G+FLVR N P Y++ F +I+ R
Sbjct: 658 PQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGKIKHCR 716
Query: 284 IEKKGVRYLMGGRTFECLDAVINRYRKEQIVEGHTLGQPLIAE 326
++++G ++G F+ L +I+ Y K + L P+ E
Sbjct: 717 VQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEE 759
Score = 35.5 bits (78), Expect = 6.7
Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 15/91 (16%)
Query: 65 EWYHGRL----------DRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHF 114
+W+HG+L +R +E + + GS+LVRES+ G Y LS+ + H
Sbjct: 549 KWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHC 608
Query: 115 RI----TAVCGDYYI-GGRQFDSLTELVGFY 140
RI A +++ FDSL +L+ Y
Sbjct: 609 RIHSRQDAGTPKFFLTDNLVFDSLYDLITHY 639
Score = 35.5 bits (78), Expect = 6.7
Identities = 17/36 (47%), Positives = 22/36 (61%)
Query: 252 AGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKK 287
A GSFLVR S+ GDY+L F N ++Q RI +
Sbjct: 578 APDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSR 613
>UniRef50_UPI0000D57912 Cluster: PREDICTED: similar to CG4200-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG4200-PA - Tribolium castaneum
Length = 1233
Score = 56.4 bits (130), Expect = 3e-06
Identities = 30/93 (32%), Positives = 49/93 (52%), Gaps = 1/93 (1%)
Query: 235 WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLM 293
W+H + K +A ++L + G+FLVRPS+N Y++ F + +I+ RI+ +G Y +
Sbjct: 687 WYHKHTGKMQADEILRRVKMEGAFLVRPSENDANCYTISFRADKKIKHCRIKLEGRLYTI 746
Query: 294 GGRTFECLDAVINRYRKEQIVEGHTLGQPLIAE 326
G FE L +IN Y + L P+ E
Sbjct: 747 GNVEFESLVELINYYENHPLYRRVKLSYPISEE 779
Score = 55.2 bits (127), Expect = 8e-06
Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 1/88 (1%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
EWYH + ++E L +G++LVR S+ Y +S+ I H RI Y
Sbjct: 686 EWYHKHTGKMQADEILRRVKMEGAFLVRPSENDANCYTISFRADKKIKHCRIKLEGRLYT 745
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERL 152
IG +F+SL EL+ +Y + L +R +L
Sbjct: 746 IGNVEFESLVELINYYEN-HPLYRRVKL 772
Score = 44.0 bits (99), Expect = 0.019
Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 13/102 (12%)
Query: 235 WFHPNCTKS-EAVDMLVKA----GPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV 289
WFH E + L+KA G G+FLVR S G+Y L F N Q+ RI K
Sbjct: 575 WFHGKLANGREEAEQLLKAYSHLGDGTFLVRASVTFVGEYCLSFWRNGQVNHCRIRSKPD 634
Query: 290 R-----YLMGGRTFECLDAVINRYRKEQIVEGH---TLGQPL 323
+ YL + F+ L ++I YR +V TL +P+
Sbjct: 635 KQHTRYYLTDAKYFDSLYSLITHYRNCPLVTAEFSITLQEPV 676
Score = 43.2 bits (97), Expect = 0.033
Identities = 31/88 (35%), Positives = 45/88 (51%), Gaps = 9/88 (10%)
Query: 65 EWYHGRL--DRYTSEERLWAASK--QGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVC 120
+W+HG+L R +E+ L A S G++LVR S G Y LS+ +NH RI +
Sbjct: 574 KWFHGKLANGREEAEQLLKAYSHLGDGTFLVRASVTFVGEYCLSFWRNGQVNHCRIRSKP 633
Query: 121 GD----YYI-GGRQFDSLTELVGFYSHC 143
YY+ + FDSL L+ Y +C
Sbjct: 634 DKQHTRYYLTDAKYFDSLYSLITHYRNC 661
>UniRef50_Q7QHE3 Cluster: ENSANGP00000022029; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000022029 - Anopheles gambiae
str. PEST
Length = 1230
Score = 56.4 bits (130), Expect = 3e-06
Identities = 29/77 (37%), Positives = 42/77 (54%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
EWYH R SE L + G++LVR S++ ++V+S+ H RI Y
Sbjct: 681 EWYHQTTTREQSEIVLNQIPQDGAFLVRPSEKGTKAFVISFRAHGKFKHCRIRVEGRLYE 740
Query: 125 IGGRQFDSLTELVGFYS 141
+GG +F+SL +LV FYS
Sbjct: 741 MGGMEFESLVDLVNFYS 757
Score = 52.8 bits (121), Expect = 4e-05
Identities = 30/103 (29%), Positives = 50/103 (48%), Gaps = 1/103 (0%)
Query: 225 PSIDPNTVFSWFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFR 283
P + + W+H T+ ++ +L + G+FLVRPS+ + + F + + + R
Sbjct: 672 PQPNKHETKEWYHQTTTREQSEIVLNQIPQDGAFLVRPSEKGTKAFVISFRAHGKFKHCR 731
Query: 284 IEKKGVRYLMGGRTFECLDAVINRYRKEQIVEGHTLGQPLIAE 326
I +G Y MGG FE L ++N Y K + TL P+ E
Sbjct: 732 IRVEGRLYEMGGMEFESLVDLVNFYSKHPLYRKVTLTYPIPRE 774
Score = 38.3 bits (85), Expect = 0.95
Identities = 32/90 (35%), Positives = 44/90 (48%), Gaps = 10/90 (11%)
Query: 234 SWFHPNCT--KSEAVDMLVK---AGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI---E 285
+WFH + + EA +L + G G+FLVR S GDY L F + RI +
Sbjct: 569 NWFHGKLSGGREEAEKLLQQFSHLGDGTFLVRESVTFVGDYCLSFWRQGKPNHCRIKLKQ 628
Query: 286 KKGVR--YLMGGRTFECLDAVINRYRKEQI 313
KGV YLM FE L ++I YR+ +
Sbjct: 629 DKGVTKYYLMENVLFESLYSLIMYYRQNAL 658
Score = 36.3 bits (80), Expect = 3.8
Identities = 29/84 (34%), Positives = 41/84 (48%), Gaps = 9/84 (10%)
Query: 66 WYHGRLD--RYTSEERLWAASK--QGSYLVRESDRKPGSYVLSYLGRTGINHFRI----- 116
W+HG+L R +E+ L S G++LVRES G Y LS+ + NH RI
Sbjct: 570 WFHGKLSGGREEAEKLLQQFSHLGDGTFLVRESVTFVGDYCLSFWRQGKPNHCRIKLKQD 629
Query: 117 TAVCGDYYIGGRQFDSLTELVGFY 140
V Y + F+SL L+ +Y
Sbjct: 630 KGVTKYYLMENVLFESLYSLIMYY 653
>UniRef50_O00899 Cluster: GAPA; n=2; Dictyostelium discoideum|Rep:
GAPA - Dictyostelium discoideum (Slime mold)
Length = 860
Score = 56.4 bits (130), Expect = 3e-06
Identities = 36/137 (26%), Positives = 68/137 (49%), Gaps = 2/137 (1%)
Query: 735 EFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLI 794
E + I ++ I S P +R++C +Q A + ++ +V+ F++ R I
Sbjct: 385 EKCIQICERFFTGIIQSLNRLPYGIRWICKQIQSIAQKNFDSKPDEIAKVIGYFVYYRFI 444
Query: 795 CPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEF--GAKEPYMEVVNPFILKN 852
A+V P A+ ++ + ++++L+ +AK LQNL L F E +M+ +N +IL
Sbjct: 445 NLAIVTPDAFEILDKELSITSRKNLVNIAKVLQNLFTLKTFQNQGSERWMQPLNKWILSK 504
Query: 853 KERMVVFLDQLSNVPDP 869
+ +L+ L V DP
Sbjct: 505 TSIVRQYLEDLIQVTDP 521
>UniRef50_UPI0000E460CB Cluster: PREDICTED: similar to V-crk sarcoma
virus CT10 oncogene homolog (avian)-like; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
V-crk sarcoma virus CT10 oncogene homolog (avian)-like -
Strongylocentrotus purpuratus
Length = 305
Score = 56.0 bits (129), Expect = 4e-06
Identities = 29/89 (32%), Positives = 48/89 (53%), Gaps = 1/89 (1%)
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
+D P D N W T+SE ++L++ PG+FLVR S PGD L N+++
Sbjct: 5 DDKAPFDDSNKHL-WHFGGITRSETDNLLIQKRPGTFLVRDSRTCPGDSVLCVSENSKVS 63
Query: 281 RFRIEKKGVRYLMGGRTFECLDAVINRYR 309
+ I +K ++++G + F L ++N YR
Sbjct: 64 HYIITRKADQFVIGDQIFSTLPDILNFYR 92
Score = 45.6 bits (103), Expect = 0.006
Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
W+ G + R + + L + G++LVR+S PG VL + ++H+ IT + I
Sbjct: 18 WHFGGITR-SETDNLLIQKRPGTFLVRDSRTCPGDSVLCVSENSKVSHYIITRKADQFVI 76
Query: 126 GGRQFDSLTELVGFY 140
G + F +L +++ FY
Sbjct: 77 GDQIFSTLPDILNFY 91
>UniRef50_Q95PW9 Cluster: Temporarily assigned gene name protein 22,
isoform a; n=3; Caenorhabditis|Rep: Temporarily assigned
gene name protein 22, isoform a - Caenorhabditis elegans
Length = 395
Score = 56.0 bits (129), Expect = 4e-06
Identities = 43/171 (25%), Positives = 76/171 (44%), Gaps = 22/171 (12%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELVE---- 221
VVA+ + ++EL+F+KG+ + H + W W+ + +G G++ R +E
Sbjct: 216 VVALYSFDAS-SSEELSFKKGERLEIVDHPEHDPDW-WMARNASGTTGLVPRNYIEVVND 273
Query: 222 ---------DLDPSIDPNTVFS-----WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPG 267
D P N W+ ++ A D+L+ G FLVR S+++PG
Sbjct: 274 SSSSKASHQDFAPQYSGNGEIPMEQQPWYFGRISRERAEDLLLHGREGEFLVRDSESNPG 333
Query: 268 DYSLFFHINNQIQRFRIEKKGVRYLMGGRTFECLDAVINRYRKEQIVEGHT 318
D S+ + + F+++ +G RTF ++A+IN Y I T
Sbjct: 334 DLSISMRGIERNKHFKVQNVDGLLKIGNRTFVDMNALINHYTTSPIFSSPT 384
Score = 52.0 bits (119), Expect = 7e-05
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
WY GR+ R +E+ L ++G +LVR+S+ PG +S G HF++ V G I
Sbjct: 301 WYFGRISRERAEDLL-LHGREGEFLVRDSESNPGDLSISMRGIERNKHFKVQNVDGLLKI 359
Query: 126 GGRQFDSLTELVGFYS 141
G R F + L+ Y+
Sbjct: 360 GNRTFVDMNALINHYT 375
>UniRef50_O97034 Cluster: PLC-gammaS; n=1; Ephydatia
fluviatilis|Rep: PLC-gammaS - Ephydatia fluviatilis
Length = 1283
Score = 56.0 bits (129), Expect = 4e-06
Identities = 35/92 (38%), Positives = 49/92 (53%), Gaps = 6/92 (6%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDR--KPG--SYVLSYLGRTGINHFRITA-VC 120
W+H L R +EE L G++L+R S++ K G +Y +S+ + H RI
Sbjct: 655 WFHENLSRSEAEEMLKKVRMDGAFLIRPSEQNTKAGQKNYAISFRAEGKVKHCRIEVDES 714
Query: 121 GDYYIGGRQFDSLTELVGFYSHCSDLLKRERL 152
G Y IG FDSLTELV +Y + L +R RL
Sbjct: 715 GQYCIGSAIFDSLTELVQYY-EANPLYRRMRL 745
Score = 49.6 bits (113), Expect = 4e-04
Identities = 28/99 (28%), Positives = 54/99 (54%), Gaps = 6/99 (6%)
Query: 216 FRELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNS----PGDYS 270
F +++ + P + + +WFH N ++SEA +ML K G+FL+RPS+ + +Y+
Sbjct: 636 FEQVLAEPVPQQNSHLGKAWFHENLSRSEAEEMLKKVRMDGAFLIRPSEQNTKAGQKNYA 695
Query: 271 LFFHINNQIQRFRIE-KKGVRYLMGGRTFECLDAVINRY 308
+ F +++ RIE + +Y +G F+ L ++ Y
Sbjct: 696 ISFRAEGKVKHCRIEVDESGQYCIGSAIFDSLTELVQYY 734
Score = 39.1 bits (87), Expect = 0.54
Identities = 31/84 (36%), Positives = 42/84 (50%), Gaps = 8/84 (9%)
Query: 65 EWYHGRL--DRYTSEERLWAASK-QGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVC 120
+W+HG+L R +E+ L G++LVRES G Y LS++ NH RI T
Sbjct: 543 KWFHGKLAGGRVAAEKLLTDYKDVNGAFLVRESTTFTGDYSLSFVRDGKYNHCRIHTKSE 602
Query: 121 GD----YYIGGRQFDSLTELVGFY 140
G Y I FDS+ EL+ Y
Sbjct: 603 GGKTRFYLIDQTLFDSIYELIMHY 626
>UniRef50_A7SXE3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 794
Score = 56.0 bits (129), Expect = 4e-06
Identities = 40/140 (28%), Positives = 69/140 (49%), Gaps = 9/140 (6%)
Query: 737 LLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPN---ERFVRTRVVSGFIFLRL 793
L+ D+ SI S E P +RY+ L+ A K+PN E ++ VV ++ R
Sbjct: 226 LIQATDKFLNSIVQSVEKIPYGMRYVAMTLRLALTEKFPNLSEEEIIK--VVGNLVYYRY 283
Query: 794 ICPALVEPRAWTLV----QRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFI 849
+ PA+V P A+ +V +R P +R+L +AK LQ A+ + + ++ +N +I
Sbjct: 284 MNPAIVAPDAFDIVSISVERGLQPEQRRNLGTIAKLLQFAASNKMYADENAHLSELNGYI 343
Query: 850 LKNKERMVVFLDQLSNVPDP 869
+ ++ F +S V DP
Sbjct: 344 AEAHKKFKKFFLDVSTVEDP 363
>UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|Rep:
Phospholipase C gamma - Chaetopterus pergamentaceus
Length = 1322
Score = 56.0 bits (129), Expect = 4e-06
Identities = 28/75 (37%), Positives = 40/75 (53%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
WYH +LDR +E+ L G++LVR++ SY +S+ I H I + I
Sbjct: 672 WYHEKLDRTRAEDMLKRIPSDGAFLVRQNGVDTNSYAISFRAEGKIKHCIIKQEGRLFTI 731
Query: 126 GGRQFDSLTELVGFY 140
G QF+SL ELV +Y
Sbjct: 732 GNAQFESLVELVNYY 746
Score = 50.8 bits (116), Expect = 2e-04
Identities = 27/109 (24%), Positives = 54/109 (49%), Gaps = 1/109 (0%)
Query: 216 FRELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKA-GPGSFLVRPSDNSPGDYSLFFH 274
F++++++ P + W+H ++ A DML + G+FLVR + Y++ F
Sbjct: 653 FQQILKEPVPQPQSHHGKPWYHEKLDRTRAEDMLKRIPSDGAFLVRQNGVDTNSYAISFR 712
Query: 275 INNQIQRFRIEKKGVRYLMGGRTFECLDAVINRYRKEQIVEGHTLGQPL 323
+I+ I+++G + +G FE L ++N Y K+ + L P+
Sbjct: 713 AEGKIKHCIIKQEGRLFTIGNAQFESLVELVNYYEKKPLYRKMKLKHPV 761
Score = 44.0 bits (99), Expect = 0.019
Identities = 29/85 (34%), Positives = 45/85 (52%), Gaps = 9/85 (10%)
Query: 65 EWYHGRLD--RYTSEERL--WAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-- 118
+W+HG+L+ R +E+ L ++ G++LVRESD G + LS+ + +NH RI +
Sbjct: 559 KWFHGKLEGGRRKAEDLLKEYSYLGDGTFLVRESDTFVGDFSLSFWRKDSVNHCRIRSKQ 618
Query: 119 ---VCGDYYIGGRQFDSLTELVGFY 140
Y I FDSL L+ Y
Sbjct: 619 ERGQTKYYLIDNLAFDSLYSLITHY 643
Score = 44.0 bits (99), Expect = 0.019
Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 10/86 (11%)
Query: 235 WFHPNCT--KSEAVDMLVK---AGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV 289
WFH + +A D+L + G G+FLVR SD GD+SL F + + RI K
Sbjct: 560 WFHGKLEGGRRKAEDLLKEYSYLGDGTFLVRESDTFVGDFSLSFWRKDSVNHCRIRSKQE 619
Query: 290 R-----YLMGGRTFECLDAVINRYRK 310
R YL+ F+ L ++I Y+K
Sbjct: 620 RGQTKYYLIDNLAFDSLYSLITHYQK 645
>UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 6
SCAF14737, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 393
Score = 55.2 bits (127), Expect = 8e-06
Identities = 25/76 (32%), Positives = 43/76 (56%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
EWY+G++ R+ +E L +G +L+R+S+ P + +S ++ HF++ Y
Sbjct: 296 EWYYGKVTRHQAEVALNQRGVEGDFLIRDSESSPHDFSISLKAQSKNKHFKVQLKESLYC 355
Query: 125 IGGRQFDSLTELVGFY 140
IG R+F S+ ELV Y
Sbjct: 356 IGQRKFHSMEELVEHY 371
Score = 52.0 bits (119), Expect = 7e-05
Identities = 41/171 (23%), Positives = 78/171 (45%), Gaps = 26/171 (15%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIF-FVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLD-- 224
V A+ P++ + +EL F+KG++ V D W G+ G++ + V LD
Sbjct: 207 VQALYPFSS-DNAEELNFEKGEVMEVVEKPENDPEWWKCRKADGQLGLVPKNYVTVLDSV 265
Query: 225 -----------PSIDPNTVF----------SWFHPNCTKSEAVDMLVKAG-PGSFLVRPS 262
P+ D + + W++ T+ +A L + G G FL+R S
Sbjct: 266 AHKQAAGPAGPPTPDCDYISPSGSGRFAGKEWYYGKVTRHQAEVALNQRGVEGDFLIRDS 325
Query: 263 DNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGGRTFECLDAVINRYRKEQI 313
++SP D+S+ ++ + F+++ K Y +G R F ++ ++ Y+K I
Sbjct: 326 ESSPHDFSISLKAQSKNKHFKVQLKESLYCIGQRKFHSMEELVEHYKKAPI 376
>UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hydra
vulgaris|Rep: Protein-tyrosine kinase HTK98 - Hydra
attenuata (Hydra) (Hydra vulgaris)
Length = 624
Score = 55.2 bits (127), Expect = 8e-06
Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDYY 124
W+HG + R +E RL + S+ G +L+RE GSYV+ + G+ H+ + G
Sbjct: 161 WFHGVIPRTEAERRLKSLSETGMFLIRERGSPRGSYVIGLFYQGGVYHYLFESNNQGQLS 220
Query: 125 I-GGRQFDSLTELVGFYSHCSD 145
I GR FD+L +V FYS S+
Sbjct: 221 IKSGRSFDNLMAVVNFYSQKSE 242
Score = 41.5 bits (93), Expect = 0.10
Identities = 30/84 (35%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQ--GSYLVRESDRKPGSYVLSYLGRTGINHFRI-T 117
P W+HGR+ R +E L + G+YL+RES + GSYVLS + H+ I
Sbjct: 4 PSLLRWFHGRITRDIAENCLQTTTSMDDGTYLLRESASEIGSYVLSVCKDKKVIHYAIQR 63
Query: 118 AVCGDYYIG-GRQFDSLTELVGFY 140
G I G QF ELV +
Sbjct: 64 QPSGMVGIADGPQFPGPVELVNHH 87
Score = 35.1 bits (77), Expect = 8.9
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 3/80 (3%)
Query: 235 WFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDY--SLFFHINNQIQRFRIEKKGVRY 291
WFH ++EA L G FL+R + G Y LF+ F +G
Sbjct: 161 WFHGVIPRTEAERRLKSLSETGMFLIRERGSPRGSYVIGLFYQGGVYHYLFESNNQGQLS 220
Query: 292 LMGGRTFECLDAVINRYRKE 311
+ GR+F+ L AV+N Y ++
Sbjct: 221 IKSGRSFDNLMAVVNFYSQK 240
>UniRef50_UPI0000E49A1C Cluster: PREDICTED: similar to Growth factor
receptor-bound protein 2; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Growth factor
receptor-bound protein 2 - Strongylocentrotus purpuratus
Length = 176
Score = 54.8 bits (126), Expect = 1e-05
Identities = 29/86 (33%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI-EKK 287
P +WF P T+ A +L++ G+FLVR S++S G YSL N +Q FRI +
Sbjct: 8 PEIAMAWFFPTITRKNAELLLMQERNGAFLVRRSESSEGLYSLSVKYNESVQHFRILQDT 67
Query: 288 GVRYLMGGRTFECLDAVINRYRKEQI 313
++ + F LDA+++ YR +
Sbjct: 68 AGKFHLWIVKFPSLDALVDYYRTTSV 93
Score = 53.6 bits (123), Expect = 2e-05
Identities = 41/147 (27%), Positives = 63/147 (42%), Gaps = 6/147 (4%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDYY 124
W+ + R +E L + G++LVR S+ G Y LS + HFRI G ++
Sbjct: 14 WFFPTITRKNAE-LLLMQERNGAFLVRRSESSEGLYSLSVKYNESVQHFRILQDTAGKFH 72
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTDELT 184
+ +F SL LV +Y S + RE + +R+ A+ + + EL
Sbjct: 73 LWIVKFPSLDALVDYYRTTS--VTRENQVSTQSVEQWSRNPQRLQALYDFDP-EEEGELC 129
Query: 185 FQKGDIF-FVHNDMGDGWLWVTAHRTG 210
F+KGDI + D W RTG
Sbjct: 130 FRKGDIITLIDKPTKDWWRGTVDGRTG 156
>UniRef50_Q4T6N5 Cluster: Chromosome 9 SCAF8684, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 9 SCAF8684, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 966
Score = 54.8 bits (126), Expect = 1e-05
Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
EWYH L R +E L + G++LVR+ +P S+ +S+ I H R+
Sbjct: 746 EWYHANLSRSQAENMLMRVPRDGAFLVRKR-AEPNSFAISFRAEGKIKHCRVQQEGQTVV 804
Query: 125 IGGRQFDSLTELVGFY 140
+G +FDSL +L+ +Y
Sbjct: 805 LGTSEFDSLVDLISYY 820
Score = 50.0 bits (114), Expect = 3e-04
Identities = 26/100 (26%), Positives = 52/100 (52%), Gaps = 2/100 (2%)
Query: 225 PSIDPNTVFSWFHPNCTKSEAVDMLVKA-GPGSFLVRPSDNSPGDYSLFFHINNQIQRFR 283
P + + W+H N ++S+A +ML++ G+FLVR P +++ F +I+ R
Sbjct: 737 PQTNAHESKEWYHANLSRSQAENMLMRVPRDGAFLVR-KRAEPNSFAISFRAEGKIKHCR 795
Query: 284 IEKKGVRYLMGGRTFECLDAVINRYRKEQIVEGHTLGQPL 323
++++G ++G F+ L +I+ Y K + L P+
Sbjct: 796 VQQEGQTVVLGTSEFDSLVDLISYYEKHPLYRKMKLRYPI 835
Score = 39.5 bits (88), Expect = 0.41
Identities = 24/64 (37%), Positives = 34/64 (53%), Gaps = 5/64 (7%)
Query: 252 AGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVR-----YLMGGRTFECLDAVIN 306
A GSFLVR S+ GDY+L F + ++Q RI + YL F+ L A+IN
Sbjct: 657 APDGSFLVRESETFVGDYTLSFWRSGRVQHCRIHSRQEAGSPKFYLTDNLVFDTLFALIN 716
Query: 307 RYRK 310
Y++
Sbjct: 717 HYQQ 720
Score = 36.3 bits (80), Expect = 3.8
Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 15/91 (16%)
Query: 65 EWYHGRL----------DRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHF 114
+W+HG+L +R SE + + GS+LVRES+ G Y LS+ + H
Sbjct: 628 KWFHGKLGAGRDGRQIAERLLSEYCMETGAPDGSFLVRESETFVGDYTLSFWRSGRVQHC 687
Query: 115 RITA--VCGD---YYIGGRQFDSLTELVGFY 140
RI + G Y FD+L L+ Y
Sbjct: 688 RIHSRQEAGSPKFYLTDNLVFDTLFALINHY 718
>UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92124
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 510
Score = 54.4 bits (125), Expect = 1e-05
Identities = 43/156 (27%), Positives = 75/156 (48%), Gaps = 15/156 (9%)
Query: 165 KKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLD 224
+K VVA+ PY + D+L F+KG+ + + G+ W + T ++G I V + D
Sbjct: 63 EKIVVALYPYEAI-HADDLGFKKGEKLKIIEEHGEWWK-ARSLTTRKEGFIPSNYVAEAD 120
Query: 225 PSIDPNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFH-INNQ--- 278
WF+ + T+ +A L+ PGS+L+R S+ S G YSL ++ Q
Sbjct: 121 TM----ETEEWFYKDITRKDAERQLLAPANKPGSYLIRESETSKGSYSLSIRDVDAQGQD 176
Query: 279 -IQRFRIEK--KGVRYLMGGRTFECLDAVINRYRKE 311
++ ++I G Y+ TF + ++I Y K+
Sbjct: 177 VVKHYKIRSLDNGGYYISPKITFSDISSMIKHYHKQ 212
Score = 51.2 bits (117), Expect = 1e-04
Identities = 33/94 (35%), Positives = 53/94 (56%), Gaps = 8/94 (8%)
Query: 65 EWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSY-----LGRTGINHFRITA 118
EW++ + R +E +L A A+K GSYL+RES+ GSY LS G+ + H++I +
Sbjct: 126 EWFYKDITRKDAERQLLAPANKPGSYLIRESETSKGSYSLSIRDVDAQGQDVVKHYKIRS 185
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSDLLKRE 150
+ G YYI + F ++ ++ Y SD L R+
Sbjct: 186 LDNGGYYISPKITFSDISSMIKHYHKQSDGLCRK 219
>UniRef50_A6SJZ0 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 1632
Score = 54.4 bits (125), Expect = 1e-05
Identities = 37/152 (24%), Positives = 71/152 (46%), Gaps = 1/152 (0%)
Query: 740 ILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNE-RFVRTRVVSGFIFLRLICPAL 798
I D L++ + P VR++C + ++P E + + +VV + F + PAL
Sbjct: 1134 ISDLFMLALESLLHRMPYGVRFICQQIFEGLCQQFPREPQLILLQVVGNWFFKFYLYPAL 1193
Query: 799 VEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVV 858
P + +V+R P +R+L VAK L +++ FG + +++ +N ++ R+
Sbjct: 1194 TTPESMGVVERQLTPLQKRNLGEVAKVLGQISSGRLFGGENMFLQPLNAYVTDAITRITE 1253
Query: 859 FLDQLSNVPDPGNSPPNSNVNFEIAKELATLH 890
+ +VPD N+ N A+ TL+
Sbjct: 1254 IFSNIISVPDAENTFDIDEFNDLYARTKPTLY 1285
>UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-receptor
type 6; n=39; Chordata|Rep: Tyrosine-protein phosphatase
non-receptor type 6 - Homo sapiens (Human)
Length = 595
Score = 54.4 bits (125), Expect = 1e-05
Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFH + + +A +L G GSFL RPS + GD+SL + +Q+ RI+ G Y L
Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDL 63
Query: 293 MGGRTFECLDAVINRYRKEQ 312
GG F L ++ Y ++Q
Sbjct: 64 YGGEKFATLTELVEYYTQQQ 83
Score = 53.2 bits (122), Expect = 3e-05
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 10/87 (11%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLG---RTG------I 111
P WYHG + +E L A + ++LVRES +PG +VLS L + G +
Sbjct: 105 PTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRV 164
Query: 112 NHFRITAVCGDYYIGGRQ-FDSLTELV 137
H ++ G Y +GG + FDSLT+LV
Sbjct: 165 THIKVMCEGGRYTVGGLETFDSLTDLV 191
Score = 48.8 bits (111), Expect = 7e-04
Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H L +E L GS+L R S + G + LS + H RI GD+Y
Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQN-SGDFYD 62
Query: 125 -IGGRQFDSLTELVGFYSHCSDLLK 148
GG +F +LTELV +Y+ +L+
Sbjct: 63 LYGGEKFATLTELVEYYTQQQGVLQ 87
Score = 39.1 bits (87), Expect = 0.54
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 12/99 (12%)
Query: 228 DPNTVFSWFHPNCTKSEAVDML-VKAGPGSFLVRPSDNSPGDYSLFFHINN--------- 277
DP T W+H + + +A +L K P +FLVR S + PGD+ L +
Sbjct: 104 DP-TSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 162
Query: 278 QIQRFRIEKKGVRYLMGG-RTFECLDAVINRYRKEQIVE 315
++ ++ +G RY +GG TF+ L ++ ++K I E
Sbjct: 163 RVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEE 201
>UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21;
Deuterostomia|Rep: Tyrosine-protein kinase CSK - Homo
sapiens (Human)
Length = 450
Score = 54.4 bits (125), Expect = 1e-05
Identities = 40/150 (26%), Positives = 67/150 (44%), Gaps = 5/150 (3%)
Query: 182 ELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFS---WFHP 238
+L F KGD+ + D + ++ G +G+I V+ + + T S WFH
Sbjct: 27 DLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKRE-GVKAGTKLSLMPWFHG 85
Query: 239 NCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGGRT- 297
T+ +A +L G FLVR S N PGDY+L + +++ +RI + +
Sbjct: 86 KITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSIDEEVY 145
Query: 298 FECLDAVINRYRKEQIVEGHTLGQPLIAEG 327
FE L ++ Y + L +P + EG
Sbjct: 146 FENLMQLVEHYTSDADGLCTRLIKPKVMEG 175
Score = 44.4 bits (100), Expect = 0.014
Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
W+HG++ R +E RL + G +LVRES PG Y L + H+RI I
Sbjct: 82 WFHGKITREQAE-RLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSI 140
Query: 126 GGR-QFDSLTELVGFYSHCSD 145
F++L +LV Y+ +D
Sbjct: 141 DEEVYFENLMQLVEHYTSDAD 161
>UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54;
Gnathostomata|Rep: Tyrosine-protein kinase BTK - Homo
sapiens (Human)
Length = 659
Score = 54.4 bits (125), Expect = 1e-05
Identities = 32/110 (29%), Positives = 61/110 (55%), Gaps = 7/110 (6%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVED 222
++ K+VVA+ Y M + ++L +KGD +F+ + W W + G++G I V +
Sbjct: 214 SELKKVVALYDYMPM-NANDLQLRKGDEYFILEESNLPW-WRARDKNGQEGYIPSNYVTE 271
Query: 223 LDPSIDPNTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSL 271
+ SI+ ++ W+ + T+S+A +L + G G F+VR S + G Y++
Sbjct: 272 AEDSIE---MYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKA-GKYTV 317
Score = 41.9 bits (94), Expect = 0.077
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 9/88 (10%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGR-TG-----INHFRITA 118
EWY + R +E+ L K+G ++VR+S K G Y +S + TG I H+ + +
Sbjct: 280 EWYSKHMTRSQAEQLLKQEGKEGGFIVRDSS-KAGKYTVSVFAKSTGDPQGVIRHYVVCS 338
Query: 119 V-CGDYYIGGRQ-FDSLTELVGFYSHCS 144
YY+ + F ++ EL+ ++ H S
Sbjct: 339 TPQSQYYLAEKHLFSTIPELINYHQHNS 366
>UniRef50_Q4RP74 Cluster: Chromosome 1 SCAF15008, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 1
SCAF15008, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 968
Score = 54.0 bits (124), Expect = 2e-05
Identities = 26/64 (40%), Positives = 36/64 (56%)
Query: 53 GERQAVLAPPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGIN 112
G R + A WYH + R +EE L A K GSYLVR+S+ PG+Y L L + ++
Sbjct: 1 GPRSTLTAMATAVWYHRDISRVQAEELLARAGKDGSYLVRDSESVPGAYALCLLFQRHVH 60
Query: 113 HFRI 116
+RI
Sbjct: 61 TYRI 64
Score = 42.3 bits (95), Expect = 0.058
Identities = 18/51 (35%), Positives = 32/51 (62%), Gaps = 1/51 (1%)
Query: 235 WFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRI 284
W+H + ++ +A ++L +AG GS+LVR S++ PG Y+L + +RI
Sbjct: 14 WYHRDISRVQAEELLARAGKDGSYLVRDSESVPGAYALCLLFQRHVHTYRI 64
>UniRef50_Q4P2J5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1774
Score = 54.0 bits (124), Expect = 2e-05
Identities = 32/115 (27%), Positives = 60/115 (52%), Gaps = 1/115 (0%)
Query: 747 SIFTSPEACPKPVRYLCGCLQRAAVAKWPNE-RFVRTRVVSGFIFLRLICPALVEPRAWT 805
+I +S P VRY+ + RA +K+P+E + +VV ++ R + PA+V P +
Sbjct: 1238 AILSSTRKMPYGVRYIAREVFRALQSKFPDEPQDALIKVVGHLVYYRYLNPAIVAPEGFD 1297
Query: 806 LVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFL 860
+V+ P +++L V+K L +A F + PY++ +N ++ ER +L
Sbjct: 1298 VVETLVGPVQRKNLAEVSKMLTQIAVGRLFNDENPYLQPLNDYVSHASERFTKWL 1352
>UniRef50_A5DHJ9 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 1413
Score = 54.0 bits (124), Expect = 2e-05
Identities = 39/181 (21%), Positives = 80/181 (44%), Gaps = 9/181 (4%)
Query: 625 PAVKALADLCR-TDRQPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLA 683
P A+A + T+ LA+S F + +L + L E+ +FR S
Sbjct: 1233 PLAGAIAQVASSTEHNMLASSFFGVFGYTKKLDKLFQVLLDEEIKHVSRSSDIFRRNSTL 1292
Query: 684 TAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQ 743
T L F + + +L++ + + ++I++ + E+ + + D+ C E + +
Sbjct: 1293 TKFLLNFTKENGFEYLESTLKPFLTEIIENDVSFEIERNEYN--DEDC---EVFVTYFTK 1347
Query: 744 ITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRA 803
+ +I S + PK ++C + ++ +++ V V FIFLR CPA++ P
Sbjct: 1348 LVDTIVNSIDRAPKSFFFICSAIYQSVKSRFEESALV---AVGSFIFLRFFCPAIISPET 1404
Query: 804 W 804
+
Sbjct: 1405 F 1405
>UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54;
Euteleostomi|Rep: Cytoplasmic protein NCK2 - Homo
sapiens (Human)
Length = 380
Score = 54.0 bits (124), Expect = 2e-05
Identities = 39/166 (23%), Positives = 77/166 (46%), Gaps = 21/166 (12%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIF-FVHNDMGDGWLWVTAHRTGEQGMIFRELV------ 220
V + P++ + + +EL F+KG+ + D W + G+ G++ + V
Sbjct: 200 VQTLYPFSSVTE-EELNFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYVVVLSDG 258
Query: 221 EDLDPSIDPNTVFS------------WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPG 267
L P+ P ++ W++ N T+ +A L + G G FL+R S++SP
Sbjct: 259 PALHPAHAPQISYTGPSSSGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPS 318
Query: 268 DYSLFFHINNQIQRFRIEKKGVRYLMGGRTFECLDAVINRYRKEQI 313
D+S+ + + + F+++ Y +G R F +D ++ Y+K I
Sbjct: 319 DFSVSLKASGKNKHFKVQLVDNVYCIGQRRFHTMDELVEHYKKAPI 364
Score = 54.0 bits (124), Expect = 2e-05
Identities = 25/76 (32%), Positives = 41/76 (53%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
EWY+G + R+ +E L +G +L+R+S+ P + +S HF++ V Y
Sbjct: 284 EWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVYC 343
Query: 125 IGGRQFDSLTELVGFY 140
IG R+F ++ ELV Y
Sbjct: 344 IGQRRFHTMDELVEHY 359
>UniRef50_P33277 Cluster: GTPase-activating protein; n=1;
Schizosaccharomyces pombe|Rep: GTPase-activating protein
- Schizosaccharomyces pombe (Fission yeast)
Length = 766
Score = 54.0 bits (124), Expect = 2e-05
Identities = 31/134 (23%), Positives = 70/134 (52%), Gaps = 4/134 (2%)
Query: 737 LLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPN-ERFVRTRVVSGFIFLRLIC 795
LL++ + ++ S + P +R++C ++ +P+ ++ GF FLR +
Sbjct: 284 LLLLTKRFLDAVLNSIDEIPYGIRWVCKLIRNLTNRLFPSISDSTICSLIGGFFFLRFVN 343
Query: 796 PALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEV-VNPFILKNKE 854
PA++ P+ L+ P + +++L +AK +Q++AN + + +++V P + + +E
Sbjct: 344 PAIISPQTSMLLDSCPSDNVRKTLATIAKIIQSVAN--GTSSTKTHLDVSFQPMLKEYEE 401
Query: 855 RMVVFLDQLSNVPD 868
++ L +L NV D
Sbjct: 402 KVHNLLRKLGNVGD 415
>UniRef50_Q4T2Z8 Cluster: Chromosome 18 SCAF10147, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 18 SCAF10147, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 279
Score = 53.6 bits (123), Expect = 2e-05
Identities = 34/93 (36%), Positives = 52/93 (55%), Gaps = 9/93 (9%)
Query: 179 DTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHP 238
+ DELTFQ+GD+ V +M D W TA G++G I + + S+ P + WF
Sbjct: 13 EADELTFQEGDVIKV-TEMEDDSGWFTAEIQGKRGYIPQNYI-----SLLP---YPWFVG 63
Query: 239 NCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSL 271
++ EA L PG FLVR S+++PG++S+
Sbjct: 64 RVSRLEAEKRLRWQDPGVFLVRESESAPGEFSV 96
>UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; Homo
sapiens|Rep: Bcr-abl1 e19a2 chimeric protein - Homo
sapiens (Human)
Length = 498
Score = 53.6 bits (123), Expect = 2e-05
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 379 WYHGPVSR-NAAEHLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 435
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 436 LYVSSESRFNTLAELVHHHSTVAD 459
Score = 46.8 bits (106), Expect = 0.003
Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
ND VA+ + D + L+ KG+ V +N G+ W A QG + +
Sbjct: 313 NDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNHNGE---WCEAQTKNGQGWVPSNYI 368
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H +++ A +L GSFLVR S++SPG S+ ++
Sbjct: 369 TPVN-SLEKH---SWYHGPVSRNAAEHLLSSGINGSFLVRESESSPGQRSISLRYEGRVY 424
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 425 HYRINTASDGKLYVSSESRFNTLAELVHHH 454
>UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27;
Fungi/Metazoa group|Rep: Tyrosine-protein kinase FRK -
Homo sapiens (Human)
Length = 505
Score = 53.6 bits (123), Expect = 2e-05
Identities = 28/83 (33%), Positives = 50/83 (60%), Gaps = 3/83 (3%)
Query: 66 WYHGRLDRYTSEERL-WAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVC-GDY 123
W+ G + R +E++L ++ +K GS+L+RES+ + G + LS L + H+RI + G +
Sbjct: 116 WFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRIKRLDEGGF 175
Query: 124 YIGGRQ-FDSLTELVGFYSHCSD 145
++ R+ F +L E V Y+ SD
Sbjct: 176 FLTRRRIFSTLNEFVSHYTKTSD 198
Score = 46.0 bits (104), Expect = 0.005
Identities = 47/169 (27%), Positives = 78/169 (46%), Gaps = 20/169 (11%)
Query: 169 VAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAH----RTGE----QGMIFRELV 220
VA+ Y + ++L+F+ GD V + + +GW W H R G QG I V
Sbjct: 48 VALFDY-QARTAEDLSFRAGDKLQVLDTLHEGW-WFARHLEKRRDGSSQQLQGYIPSNYV 105
Query: 221 -EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINN 277
ED +P WF +S+A L+ + GSFL+R S++ G++SL
Sbjct: 106 AEDRSLQAEP-----WFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGA 160
Query: 278 QIQRFRIEK--KGVRYLMGGRTFECLDAVINRYRKEQIVEGHTLGQPLI 324
++ +RI++ +G +L R F L+ ++ Y K LG+P +
Sbjct: 161 VVKHYRIKRLDEGGFFLTRRRIFSTLNEFVSHYTKTSDGLCVKLGKPCL 209
>UniRef50_Q4SS18 Cluster: Chromosome undetermined SCAF14482, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14482, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 621
Score = 52.8 bits (121), Expect = 4e-05
Identities = 35/95 (36%), Positives = 50/95 (52%), Gaps = 4/95 (4%)
Query: 54 ERQAVLAPPETEWYHGRLDRYTSEERLWAASK-QGSYLVRESDRKPGSYVLSYLGRTGIN 112
+R A+ A W+HG + R SE RL S+ G +LVR+ D GSY L L +
Sbjct: 151 KRIAITAHERMVWFHGAITREGSEPRLQNGSRINGRFLVRQRDTN-GSYALCLLHEGQVM 209
Query: 113 HFRITA-VCGDYYI-GGRQFDSLTELVGFYSHCSD 145
H+R+ G I G++FD+L +LV YS+ D
Sbjct: 210 HYRVDRDQAGKLSIPEGKKFDTLWQLVEHYSYKPD 244
>UniRef50_A2RQD6 Cluster: Bcr-abl1 e6a2 chimeric protein; n=10;
Euteleostomi|Rep: Bcr-abl1 e6a2 chimeric protein - Homo
sapiens (Human)
Length = 585
Score = 52.8 bits (121), Expect = 4e-05
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 466 WYHGPVSR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 522
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 523 LYVSSESRFNTLAELVHHHSTVAD 546
Score = 46.0 bits (104), Expect = 0.005
Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
ND VA+ + D + L+ KG+ V +N G+ W A QG + +
Sbjct: 400 NDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNHNGE---WCEAQTKNGQGWVPSNYI 455
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H +++ A +L GSFLVR S++SPG S+ ++
Sbjct: 456 TPVN-SLEKH---SWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY 511
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 512 HYRINTASDGKLYVSSESRFNTLAELVHHH 541
>UniRef50_A2RQD3 Cluster: Bcr-abl1 e13a3 chimeric protein; n=21;
Eumetazoa|Rep: Bcr-abl1 e13a3 chimeric protein - Homo
sapiens (Human)
Length = 235
Score = 52.8 bits (121), Expect = 4e-05
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 116 WYHGPVSR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 172
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 173 LYVSSESRFNTLAELVHHHSTVAD 196
Score = 41.5 bits (93), Expect = 0.10
Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 234 SWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIE--KKGVRY 291
SW+H +++ A +L GSFLVR S++SPG S+ ++ +RI G Y
Sbjct: 115 SWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY 174
Query: 292 LMGGRTFECLDAVINRY 308
+ F L +++ +
Sbjct: 175 VSSESRFNTLAELVHHH 191
>UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming
protein Abl; n=15; root|Rep: Tyrosine-protein kinase
transforming protein Abl - Abelson murine leukemia virus
Length = 746
Score = 52.8 bits (121), Expect = 4e-05
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 13 WYHGPVSR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 69
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 70 LYVSSESRFNTLAELVHHHSTVAD 93
Score = 41.5 bits (93), Expect = 0.10
Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 234 SWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIE--KKGVRY 291
SW+H +++ A +L GSFLVR S++SPG S+ ++ +RI G Y
Sbjct: 12 SWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY 71
Query: 292 LMGGRTFECLDAVINRY 308
+ F L +++ +
Sbjct: 72 VSSESRFNTLAELVHHH 88
>UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase
ABL1; n=35; root|Rep: Proto-oncogene tyrosine-protein
kinase ABL1 - Homo sapiens (Human)
Length = 1130
Score = 52.8 bits (121), Expect = 4e-05
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 127 WYHGPVSR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 183
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 184 LYVSSESRFNTLAELVHHHSTVAD 207
Score = 46.0 bits (104), Expect = 0.005
Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
ND VA+ + D + L+ KG+ V +N G+ W A QG + +
Sbjct: 61 NDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNHNGE---WCEAQTKNGQGWVPSNYI 116
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H +++ A +L GSFLVR S++SPG S+ ++
Sbjct: 117 TPVN-SLEKH---SWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY 172
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 173 HYRINTASDGKLYVSSESRFNTLAELVHHH 202
>UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to
protein-tyrosine kinase; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to protein-tyrosine
kinase - Strongylocentrotus purpuratus
Length = 837
Score = 52.4 bits (120), Expect = 5e-05
Identities = 28/82 (34%), Positives = 42/82 (51%), Gaps = 2/82 (2%)
Query: 66 WYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
W+HG +DR + E + +K G +L+R S KP + VLS + +F I +Y
Sbjct: 351 WFHGSMDRKKALESIQKHGAKDGQFLLRSSANKPDTMVLSMAANGTVFNFEINTKMESFY 410
Query: 125 I-GGRQFDSLTELVGFYSHCSD 145
I G FD+L +L+ YS D
Sbjct: 411 IDDGPYFDTLEQLIDHYSRYDD 432
Score = 51.6 bits (118), Expect = 1e-04
Identities = 29/79 (36%), Positives = 44/79 (55%), Gaps = 5/79 (6%)
Query: 66 WYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
W+HGR+ R T+ L S +G++LVRES + G YV+S + HF+I + GD+Y
Sbjct: 76 WFHGRITRDTAVHVLKGNGSGEGTFLVRESTSRSGDYVVSIMHNGLPQHFQIQCM-GDFY 134
Query: 125 I---GGRQFDSLTELVGFY 140
G F L +L+ +Y
Sbjct: 135 YKIDNGPLFQGLDQLINYY 153
Score = 51.2 bits (117), Expect = 1e-04
Identities = 33/95 (34%), Positives = 48/95 (50%), Gaps = 4/95 (4%)
Query: 219 LVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVK--AGPGSFLVRPSDNSPGDYSLFFHIN 276
L+ D+ + + WFH T+ AV +L +G G+FLVR S + GDY + N
Sbjct: 60 LINDVAAAKEEEKDLLWFHGRITRDTAVHVLKGNGSGEGTFLVRESTSRSGDYVVSIMHN 119
Query: 277 NQIQRFRIEKKGVRY--LMGGRTFECLDAVINRYR 309
Q F+I+ G Y + G F+ LD +IN YR
Sbjct: 120 GLPQHFQIQCMGDFYYKIDNGPLFQGLDQLINYYR 154
Score = 40.7 bits (91), Expect = 0.18
Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 235 WFHPNCTKSEAVDMLVKAGP--GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVR-Y 291
WFH + + +A++ + K G G FL+R S N P L N + F I K Y
Sbjct: 351 WFHGSMDRKKALESIQKHGAKDGQFLLRSSANKPDTMVLSMAANGTVFNFEINTKMESFY 410
Query: 292 LMGGRTFECLDAVINRYRK 310
+ G F+ L+ +I+ Y +
Sbjct: 411 IDDGPYFDTLEQLIDHYSR 429
>UniRef50_UPI0000498DA6 Cluster: hypothetical protein 6.t00064; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
protein 6.t00064 - Entamoeba histolytica HM-1:IMSS
Length = 449
Score = 52.4 bits (120), Expect = 5e-05
Identities = 44/159 (27%), Positives = 73/159 (45%), Gaps = 8/159 (5%)
Query: 645 VLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAIS 704
+L F G+ L L+ E+ + LFRG S+ T V E+++ +C FLQ IS
Sbjct: 128 LLKFFKSRGKLTHLITNLSDIEIETTNYNNELFRGNSVFTRVFSEYLKNYCNEFLQLIIS 187
Query: 705 ETIQKLIDSKQTAELNPTKMDSPDDACNN---AEFLLMILDQITLSIFTSPEACPKPVRY 761
IQ++I K+ N + + DD+ N A + +L+++ +SI + P +RY
Sbjct: 188 -PIQEII--KEVKTKNQPSILTGDDSLNGLLLACTIKDVLEKMAVSITKNTCLLPPHLRY 244
Query: 762 LCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVE 800
+ + + E V+ IFLR I P L +
Sbjct: 245 ILRHIYNSVYLIRGEE--ASKHVLETLIFLRFILPPLAQ 281
>UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 485
Score = 52.4 bits (120), Expect = 5e-05
Identities = 25/79 (31%), Positives = 43/79 (54%), Gaps = 2/79 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK--KGVRYL 292
WFH ++ +A +L G FLVR S N PGDY+L + +++ +R+ + KG+ +
Sbjct: 109 WFHGRISREDAEKLLTPPKNGRFLVRESQNYPGDYTLCVSYDGRVENYRVRRNEKGLVTV 168
Query: 293 MGGRTFECLDAVINRYRKE 311
F+ L ++ Y+KE
Sbjct: 169 DDDEYFDNLIKLVEHYQKE 187
Score = 44.4 bits (100), Expect = 0.014
Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVL--SYLGRTGINHFRITA-VCGD 122
W+HGR+ R +E +L K G +LVRES PG Y L SY GR + ++R+ G
Sbjct: 109 WFHGRISREDAE-KLLTPPKNGRFLVRESQNYPGDYTLCVSYDGR--VENYRVRRNEKGL 165
Query: 123 YYIGGRQ-FDSLTELVGFYSHCSD 145
+ + FD+L +LV Y +D
Sbjct: 166 VTVDDDEYFDNLIKLVEHYQKEAD 189
>UniRef50_A2FB27 Cluster: GTPase-activator protein, putative; n=1;
Trichomonas vaginalis G3|Rep: GTPase-activator protein,
putative - Trichomonas vaginalis G3
Length = 2146
Score = 52.4 bits (120), Expect = 5e-05
Identities = 43/188 (22%), Positives = 77/188 (40%), Gaps = 7/188 (3%)
Query: 657 ELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQK---LIDS 713
EL E + TLFRG + V +++ +L ++ I+K L +S
Sbjct: 1014 ELTNSTIVYATEEELNRTTLFRGNGTPSKVFSAYIQMVANEWLLGLMTPIIRKVTLLAES 1073
Query: 714 KQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAK 773
+ ++ T++D ++ N E + + E P+ + L + V +
Sbjct: 1074 GVSFHIDQTRLDPHENINENREQFRQVFSDFVNQFENNIETMPRGLIKAAQILYNSIVNQ 1133
Query: 774 WPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLV 833
+FV + ++ FIFLR ICP L+EP + A P + L+ ++ L A
Sbjct: 1134 ---SQFVAVQAIASFIFLRFICPTLIEPTRAGYTE-AIPEQTRTCLVHLSSLLMVAAVRN 1189
Query: 834 EFGAKEPY 841
AK P+
Sbjct: 1190 RVDAKRPH 1197
>UniRef50_Q6CFR5 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 1367
Score = 52.4 bits (120), Expect = 5e-05
Identities = 53/209 (25%), Positives = 95/209 (45%), Gaps = 9/209 (4%)
Query: 733 NAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLR 792
N + L + + +I +S P VRY+ R+ +P+E R V G + +
Sbjct: 827 NLQRLRELTSEFLHTIESSVLQLPYHVRYVARECYRSVQKTFPHESEDRHLAVIGVVLVS 886
Query: 793 L-ICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILK 851
L + P +V P + + + A P +R+L VAK L +A+L F + Y++ +N +I +
Sbjct: 887 LFVIPPIVAPDDYGVCESAIGPAQRRNLGEVAKMLAQIASLRLFSRENVYLQPLNDYIKQ 946
Query: 852 NKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATL----HHICVAH---LTELQGLA 904
+ R+ L + +V DP S + A + TL + I V H E++ +A
Sbjct: 947 TQPRVRAMLKLVVDVCDPEQYYETSTTDDVTATKRPTLFLRTNDIFVIHNLICREIETVA 1006
Query: 905 KN-QPAIRKLVTVTEMLTKHKQKYLEMIR 932
+ + +R++VT L + L M R
Sbjct: 1007 PDAKDPLREVVTDMGALPSSATEVLNMAR 1035
>UniRef50_P43405 Cluster: Tyrosine-protein kinase SYK; n=23;
Theria|Rep: Tyrosine-protein kinase SYK - Homo sapiens
(Human)
Length = 635
Score = 52.4 bits (120), Expect = 5e-05
Identities = 35/96 (36%), Positives = 51/96 (53%), Gaps = 4/96 (4%)
Query: 57 AVLAPPETEWYHGRLDRYTSEERLWAASK-QGSYLVRESDRKPGSYVLSYLGRTGINHFR 115
A A + W+HG++ R SE+ + SK G +L+R D GSY L L + H+R
Sbjct: 159 ATTAHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNN-GSYALCLLHEGKVLHYR 217
Query: 116 ITA-VCGDYYI-GGRQFDSLTELVGFYSHCSDLLKR 149
I G I G++FD+L +LV YS+ +D L R
Sbjct: 218 IDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLR 253
>UniRef50_UPI00015B564A Cluster: PREDICTED: similar to CRK protein;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to CRK
protein - Nasonia vitripennis
Length = 298
Score = 52.0 bits (119), Expect = 7e-05
Identities = 40/157 (25%), Positives = 70/157 (44%), Gaps = 13/157 (8%)
Query: 63 ETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAV-CG 121
++ WY G + R + + L + + G +LVR+S G +VL + ++H+ I + G
Sbjct: 10 KSSWYFGAMSRQDASDLLMSEKEGGVFLVRDSISIQGDFVLCVREDSKVSHYIINKIQQG 69
Query: 122 D---YYIGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMP 178
D Y IG + F + L+ FY K L +RV+A +
Sbjct: 70 DQIRYRIGDQIFPDIPNLLAFY-------KLHYLDTTPLIRPAPRKIQRVIARYDFDG-N 121
Query: 179 DTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMI 215
D D+L F+KG+I + + + W W + G+ G +
Sbjct: 122 DPDDLPFRKGEILTIISKDEEQW-WTAKNSLGQTGSV 157
Score = 36.7 bits (81), Expect = 2.9
Identities = 24/89 (26%), Positives = 46/89 (51%), Gaps = 5/89 (5%)
Query: 226 SIDPNTVFSWFHPNCTKSEAVDMLVKAGPGS-FLVRPSDNSPGDYSLFFHINNQIQRFRI 284
+ D N SW+ ++ +A D+L+ G FLVR S + GD+ L ++++ + I
Sbjct: 4 TFDQNDKSSWYFGAMSRQDASDLLMSEKEGGVFLVRDSISIQGDFVLCVREDSKVSHYII 63
Query: 285 EK--KG--VRYLMGGRTFECLDAVINRYR 309
K +G +RY +G + F + ++ Y+
Sbjct: 64 NKIQQGDQIRYRIGDQIFPDIPNLLAFYK 92
>UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2;
Caenorhabditis|Rep: C-terminal src kinase protein 1 -
Caenorhabditis elegans
Length = 539
Score = 52.0 bits (119), Expect = 7e-05
Identities = 29/112 (25%), Positives = 54/112 (48%), Gaps = 2/112 (1%)
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMG 294
WFH ++ +L G+FLVR S N PGD++L + +++ +RIE+ L
Sbjct: 151 WFHSMISRENTEKLLRGKPDGTFLVRESTNFPGDFTLCMSFHGKVEHYRIEQTSGGQLTC 210
Query: 295 GRT--FECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQSTTGAAAEKI 344
+ F L +++ Y+++ H L P+I E T S++ ++ +
Sbjct: 211 DKEEYFSNLTQLVSHYKRDADGLCHRLVTPIICETATFSSNGSSSFGSSSTV 262
Score = 46.4 bits (105), Expect = 0.004
Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
W+H + R +E +L G++LVRES PG + L + H+RI G
Sbjct: 151 WFHSMISRENTE-KLLRGKPDGTFLVRESTNFPGDFTLCMSFHGKVEHYRIEQTSGGQLT 209
Query: 126 GGRQ--FDSLTELVGFYSHCSD 145
++ F +LT+LV Y +D
Sbjct: 210 CDKEEYFSNLTQLVSHYKRDAD 231
>UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma
mansoni|Rep: Src tyrosine kinase - Schistosoma mansoni
(Blood fluke)
Length = 647
Score = 52.0 bits (119), Expect = 7e-05
Identities = 46/170 (27%), Positives = 74/170 (43%), Gaps = 15/170 (8%)
Query: 169 VAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
VA+ Y K D D+L KG IF + ++ W + TG +G + + + + S++
Sbjct: 161 VALHDYVKRVD-DDLNMTKGQIFNILDNSHCDWWYAECVSTGNRGYVPKNHLAAVT-SLE 218
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAGP--GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK 286
N W+ + EA L G GSFLVR S++ +YSL N ++ +RI
Sbjct: 219 SN---EWYFGELKRIEAEHYLQLPGNDHGSFLVRISESQSSEYSLSVREENTVKHYRIRS 275
Query: 287 KGVR--------YLMGGRTFECLDAVINRYRKEQIVEGHTLGQPLIAEGH 328
+ R Y+ F + ++N Y + Q LG+P I H
Sbjct: 276 RYSRTDPTLKRFYISRQLPFVNIQQLVNHYLENQSGLCCRLGKPCIRPTH 325
Score = 39.9 bits (89), Expect = 0.31
Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 57 AVLAPPETEWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSYLGRTGINHFR 115
AV + EWY G L R +E L + GS+LVR S+ + Y LS + H+R
Sbjct: 213 AVTSLESNEWYFGELKRIEAEHYLQLPGNDHGSFLVRISESQSSEYSLSVREENTVKHYR 272
Query: 116 I 116
I
Sbjct: 273 I 273
>UniRef50_P05433 Cluster: P47(GAG-CRK) protein; n=3; root|Rep:
P47(GAG-CRK) protein - Avian sarcoma virus (strain CT10)
Length = 440
Score = 52.0 bits (119), Expect = 7e-05
Identities = 51/184 (27%), Positives = 78/184 (42%), Gaps = 25/184 (13%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAV--CGD- 122
WY GRL R + L + G++LVR+S PG +VLS + ++H+ + ++ G
Sbjct: 248 WYWGRLSRGDAVSLL-QGQRHGTFLVRDSGSIPGDFVLSVSESSRVSHYIVNSLGPAGGR 306
Query: 123 ----------------YYIGGRQFDSLTELVGFYS-HCSD---LLKRERLXXXXXXXXXX 162
+ IG + FDSL L+ FY H D L++
Sbjct: 307 RAGGEGPGAPGLNPTRFLIGDQVFDSLPSLLEFYKIHYLDTTTLIEPVSRSRQNSGVILR 366
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVED 222
++ V L K D +L F+KGDI + + + W W G++GMI VE
Sbjct: 367 QEEVEYVRALFDFKGNDDGDLPFKKGDILKIRDKPEEQW-WNAEDMDGKRGMIPVPYVEK 425
Query: 223 LDPS 226
PS
Sbjct: 426 CRPS 429
Score = 36.3 bits (80), Expect = 3.8
Identities = 16/55 (29%), Positives = 30/55 (54%)
Query: 234 SWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKG 288
SW+ ++ +AV +L G+FLVR S + PGD+ L ++++ + + G
Sbjct: 247 SWYWGRLSRGDAVSLLQGQRHGTFLVRDSGSIPGDFVLSVSESSRVSHYIVNSLG 301
>UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming
protein Abl; n=57; root|Rep: Tyrosine-protein kinase
transforming protein Abl - Feline sarcoma virus (strain
Hardy-Zuckerman 2)
Length = 439
Score = 52.0 bits (119), Expect = 7e-05
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 76 WYHGPVSR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 132
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 133 LYVSPESRFNTLAELVHHHSTVAD 156
Score = 45.2 bits (102), Expect = 0.008
Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
ND VA+ + D + L+ KG+ V +N G+ W A QG + +
Sbjct: 10 NDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNHNGE---WCEAQTKNGQGWVPSNYI 65
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H +++ A +L GSFLVR S++SPG S+ ++
Sbjct: 66 TPVN-SLEKH---SWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY 121
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 122 HYRINTASDGKLYVSPESRFNTLAELVHHH 151
>UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to
proto-oncogene tyrosine-protein kinase abl1; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to
proto-oncogene tyrosine-protein kinase abl1 - Nasonia
vitripennis
Length = 1522
Score = 51.6 bits (118), Expect = 1e-04
Identities = 46/139 (33%), Positives = 66/139 (47%), Gaps = 18/139 (12%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRITAVC-GD 122
WYHGR+ R + E L ++ GS+LVRES+ PG S L Y GR + H+RI G
Sbjct: 175 WYHGRISR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINEDSDGK 231
Query: 123 YYIGGRQ-FDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTD 181
Y+ F++L ELV +S +D L + L K+ + P + P+ D
Sbjct: 232 MYVTTESIFNTLAELVHHHSMLADGLITQLLYPA--------PKRNKPTVFPLS--PEPD 281
Query: 182 ELTFQKGDIFFVHNDMGDG 200
E + DI H +G G
Sbjct: 282 EWEINRTDIVMRHK-LGGG 299
Score = 44.8 bits (101), Expect = 0.011
Identities = 34/133 (25%), Positives = 66/133 (49%), Gaps = 12/133 (9%)
Query: 181 DELTFQKGDIFFV--HNDMGDGWLWVTAHRT-GEQGMIFRELVEDLDPSIDPNTVFSWFH 237
++L +KG+ + +N G+ W AH + G+ G + V ++ S++ + SW+H
Sbjct: 125 NQLGLKKGEQVRILSYNKSGE---WCEAHSSSGQVGWVPSNYVTPVN-SLEKH---SWYH 177
Query: 238 PNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGG 295
+++ A +L GSFLVR S++SPG S+ ++ +RI + G Y+
Sbjct: 178 GRISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDSDGKMYVTTE 237
Query: 296 RTFECLDAVINRY 308
F L +++ +
Sbjct: 238 SIFNTLAELVHHH 250
>UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN
full-length enriched library, clone:9930020J04
product:similar to epidermal growth factor-receptor-
binding protein GRB-4; n=5; Eutheria|Rep: Adult female
vagina cDNA, RIKEN full-length enriched library,
clone:9930020J04 product:similar to epidermal growth
factor-receptor- binding protein GRB-4 - Mus musculus
(Mouse)
Length = 123
Score = 51.6 bits (118), Expect = 1e-04
Identities = 23/80 (28%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Query: 235 WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLM 293
W++ T+ +A L + G G FL+R S++SP D+S+ + + F+++ K Y +
Sbjct: 28 WYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYCI 87
Query: 294 GGRTFECLDAVINRYRKEQI 313
G R F ++ ++ Y+K I
Sbjct: 88 GQRKFSTMEELVEHYKKAPI 107
Score = 51.6 bits (118), Expect = 1e-04
Identities = 23/75 (30%), Positives = 41/75 (54%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
WY+G++ R+ +E L +G +L+R+S+ P + +S + HF++ Y I
Sbjct: 28 WYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYCI 87
Query: 126 GGRQFDSLTELVGFY 140
G R+F ++ ELV Y
Sbjct: 88 GQRKFSTMEELVEHY 102
>UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole
genome shotgun sequence; n=3; Tetraodontidae|Rep:
Chromosome undetermined SCAF5507, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1116
Score = 51.2 bits (117), Expect = 1e-04
Identities = 28/78 (35%), Positives = 45/78 (57%), Gaps = 3/78 (3%)
Query: 66 WYHGRLDRYTSEERLWAA-SKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDY 123
WY+G ++R +E+ L A+ +K GS+LVR S+ Y +S + HFRI + G Y
Sbjct: 250 WYYGNINRVKAEKLLLASQNKDGSFLVRISESHSDEYTISARSEGKVFHFRIQRSSIGAY 309
Query: 124 YIGGR-QFDSLTELVGFY 140
++ R F +L EL+ +Y
Sbjct: 310 FVSDRISFATLGELISYY 327
Score = 49.6 bits (113), Expect = 4e-04
Identities = 30/93 (32%), Positives = 51/93 (54%), Gaps = 7/93 (7%)
Query: 59 LAPPET----EWYHGRLDRYTSEERLWAA-SKQGSYLVRESDRKPGSYVLSYLGRTGINH 113
LAP E+ W+ G L+R ++ L A + +G++L+R S++ YVLS + H
Sbjct: 58 LAPAESGQTQPWFFGTLNRLQAQSHLLAPENSEGAFLIRVSEKDNVGYVLSVRSGDQVKH 117
Query: 114 FRITAVCGD-YYI-GGRQFDSLTELVGFYSHCS 144
+++ + +Y+ GR+F SL ELV +Y S
Sbjct: 118 YKVLQTDQNRFYVEPGRRFSSLAELVDYYQKTS 150
Score = 42.7 bits (96), Expect = 0.044
Identities = 37/149 (24%), Positives = 66/149 (44%), Gaps = 11/149 (7%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRE-LVED--LDPSIDPNTVFSWFH 237
+ L+F++GD+F V + D W + R G + LV L P+ T WF
Sbjct: 16 EHLSFREGDLFRVLSRRDDWW---SVRRIDASGRVLDSGLVPGNYLAPAESGQTQ-PWFF 71
Query: 238 PNCTKSEAVDMLV--KAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVR--YLM 293
+ +A L+ + G+FL+R S+ Y L +Q++ +++ + Y+
Sbjct: 72 GTLNRLQAQSHLLAPENSEGAFLIRVSEKDNVGYVLSVRSGDQVKHYKVLQTDQNRFYVE 131
Query: 294 GGRTFECLDAVINRYRKEQIVEGHTLGQP 322
GR F L +++ Y+K + LG P
Sbjct: 132 PGRRFSSLAELVDYYQKTSLNNAGPLGNP 160
Score = 39.5 bits (88), Expect = 0.41
Identities = 20/63 (31%), Positives = 36/63 (57%), Gaps = 2/63 (3%)
Query: 84 SKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGD-YYI-GGRQFDSLTELVGFYS 141
+ +G++L+R S++ YVLS + H+++ + +Y+ GR+F SL ELV +Y
Sbjct: 733 NSEGAFLIRVSEKDNVGYVLSVRSGDQVKHYKVLQTDQNRFYVEPGRRFSSLAELVDYYQ 792
Query: 142 HCS 144
S
Sbjct: 793 KTS 795
Score = 38.7 bits (86), Expect = 0.72
Identities = 24/92 (26%), Positives = 48/92 (52%), Gaps = 4/92 (4%)
Query: 235 WFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV-RY 291
W++ N + +A +L+ + GSFLVR S++ +Y++ ++ FRI++ + Y
Sbjct: 250 WYYGNINRVKAEKLLLASQNKDGSFLVRISESHSDEYTISARSEGKVFHFRIQRSSIGAY 309
Query: 292 LMGGR-TFECLDAVINRYRKEQIVEGHTLGQP 322
+ R +F L +I+ Y++ G L +P
Sbjct: 310 FVSDRISFATLGELISYYQRNNRSLGVLLEEP 341
>UniRef50_Q7QG48 Cluster: ENSANGP00000010943; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000010943 - Anopheles gambiae
str. PEST
Length = 256
Score = 51.2 bits (117), Expect = 1e-04
Identities = 39/157 (24%), Positives = 67/157 (42%), Gaps = 14/157 (8%)
Query: 64 TEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAV---- 119
+ WY G + R + + L + G +LVR+S G +VL + ++H+ I +
Sbjct: 10 SSWYFGAMSRQDATDLLLNERESGVFLVRDSTTIVGDFVLCVREDSKVSHYIINKLPSGD 69
Query: 120 -CGDYYIGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMP 178
C Y IG + F L +L+ FY K L ++V+ +
Sbjct: 70 ECFVYRIGDQTFADLPDLLSFY-------KLHYLDTTPLRRPMVRRLEKVIGKFDFDG-S 121
Query: 179 DTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMI 215
D D+L F+KG+I + + + W W + G+ G I
Sbjct: 122 DPDDLPFKKGEILHIISKDEEQW-WTARNGAGQTGQI 157
>UniRef50_Q5DBN4 Cluster: SJCHGC05332 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC05332 protein - Schistosoma
japonicum (Blood fluke)
Length = 312
Score = 51.2 bits (117), Expect = 1e-04
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 22/156 (14%)
Query: 170 AILPYTKMP-DTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
AI Y P + DEL F+KG + M + W A + ++GM+ + S+
Sbjct: 3 AIANYAFSPTEPDELGFEKGSTLCIVG-MEEDPNWYKARQGNQEGMVPANYI-----SLC 56
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAGP---------GSFLVRPSDNSPGDYSLFFHINNQI 279
P+ W+ P C++ EA L++ P G+F++R S+N PG +S+ + +
Sbjct: 57 PHP---WYIPKCSRREAEARLLETDPNTHRDVQPDGAFVLRQSENDPGHFSISVKEGSSV 113
Query: 280 QRFRI--EKKGVRYLMGGRTFECLDAVINRYRKEQI 313
FRI + G +Y + F ++A+I+ +R + I
Sbjct: 114 LHFRIFFDPSG-KYYIWTNKFSSINALIDYHRHQTI 148
Score = 41.1 bits (92), Expect = 0.13
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 9/86 (10%)
Query: 66 WYHGRLDRYTSEERLWAASKQ--------GSYLVRESDRKPGSYVLSYLGRTGINHFRI- 116
WY + R +E RL G++++R+S+ PG + +S + + HFRI
Sbjct: 60 WYIPKCSRREAEARLLETDPNTHRDVQPDGAFVLRQSENDPGHFSISVKEGSSVLHFRIF 119
Query: 117 TAVCGDYYIGGRQFDSLTELVGFYSH 142
G YYI +F S+ L+ ++ H
Sbjct: 120 FDPSGKYYIWTNKFSSINALIDYHRH 145
>UniRef50_UPI00015B636F Cluster: PREDICTED: similar to IQ motif
containing GTPase activating protein 2; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to IQ motif
containing GTPase activating protein 2 - Nasonia
vitripennis
Length = 1533
Score = 50.8 bits (116), Expect = 2e-04
Identities = 36/133 (27%), Positives = 63/133 (47%), Gaps = 5/133 (3%)
Query: 732 NNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRT-RVVSGFIF 790
N L + ++ SI TS + P + Y+ L + K+P+E +VV I+
Sbjct: 1020 NGIRLLQRTVLELLRSIITSRDLIPYGMLYMSKVLNDTLIEKFPDELEKNILKVVGNLIY 1079
Query: 791 LRLICPALVEPRAWTLV----QRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVN 846
I A+V P A+ ++ +R +R+L +AK LQ A+ FG + ++ +N
Sbjct: 1080 YHFINAAIVAPDAFEIITLPIERTLSNDQRRNLASIAKILQFAASKKGFGEEAAHLVCLN 1139
Query: 847 PFILKNKERMVVF 859
PFI++ E+ F
Sbjct: 1140 PFIIECHEKFKKF 1152
>UniRef50_Q98TP5 Cluster: C-Src protein-tyrosine kinase; n=5;
Euteleostomi|Rep: C-Src protein-tyrosine kinase -
Platichthys flesus (European flounder)
Length = 120
Score = 50.8 bits (116), Expect = 2e-04
Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 1/98 (1%)
Query: 231 TVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFR-IEKKGV 289
++ WFH T+++A +L G FLVR S N PGDY+L + +++ +R I G
Sbjct: 14 SLMPWFHGKITRNQAEQLLCPPETGLFLVRESTNFPGDYTLCVSCDGKVEHYRIIYHNGK 73
Query: 290 RYLMGGRTFECLDAVINRYRKEQIVEGHTLGQPLIAEG 327
+ FE L ++ Y K+ L +P + EG
Sbjct: 74 LTIDEEEYFENLMQLVEHYTKDADGLCTRLLKPKVEEG 111
Score = 46.0 bits (104), Expect = 0.005
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
W+HG++ R +E+ L + G +LVRES PG Y L + H+RI G I
Sbjct: 18 WFHGKITRNQAEQLL-CPPETGLFLVRESTNFPGDYTLCVSCDGKVEHYRIIYHNGKLTI 76
Query: 126 GGRQ-FDSLTELVGFYSHCSD 145
+ F++L +LV Y+ +D
Sbjct: 77 DEEEYFENLMQLVEHYTKDAD 97
>UniRef50_Q7T0U4 Cluster: MGC68984 protein; n=2; Xenopus|Rep:
MGC68984 protein - Xenopus laevis (African clawed frog)
Length = 266
Score = 50.4 bits (115), Expect = 2e-04
Identities = 32/88 (36%), Positives = 50/88 (56%), Gaps = 8/88 (9%)
Query: 66 WYHGRLDRYTSEERLWAAS-KQGSYLVRESDRKPGSYVLS-----YLGRTGINHFRITAV 119
W + ++R +EE L S + GS+L+RES+ + GSY LS + R I H+RI +
Sbjct: 89 WLYKGINREKAEELLMVNSNRSGSFLIRESETRSGSYTLSIRKTNHTSRDSIKHYRIHQL 148
Query: 120 -CGDYYIGGR-QFDSLTELVGFYSHCSD 145
G +YI R F +L ++V +YS +D
Sbjct: 149 DNGWFYIAPRLTFATLQDMVDYYSEVAD 176
Score = 35.5 bits (78), Expect = 6.7
Identities = 42/174 (24%), Positives = 77/174 (44%), Gaps = 23/174 (13%)
Query: 164 DKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDL 223
DK VA+ + TD L+ G+ + ++ GD WL V++ TG++ + V +
Sbjct: 28 DKCIFVALYNFPLSGQTD-LSIHFGEQLNILSEDGD-WLKVSSASTGQECYLPTNYVAKV 85
Query: 224 DPSIDPNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINN---- 277
W + + +A ++L+ GSFL+R S+ G Y+L N
Sbjct: 86 --------CNRWLYKGINREKAEELLMVNSNRSGSFLIRESETRSGSYTLSIRKTNHTSR 137
Query: 278 -QIQRFRIEK--KGVRYLMGGRTFECLDAVINRYRKEQIVEG--HTLGQPLIAE 326
I+ +RI + G Y+ TF L +++ Y ++ +G TL +P + +
Sbjct: 138 DSIKHYRIHQLDNGWFYIAPRLTFATLQDMVDYY--SEVADGICCTLTEPCVVQ 189
>UniRef50_Q1KL02 Cluster: Chimerin 2; n=3; Tetraodontidae|Rep:
Chimerin 2 - Fugu rubripes (Japanese pufferfish)
(Takifugu rubripes)
Length = 676
Score = 50.4 bits (115), Expect = 2e-04
Identities = 27/72 (37%), Positives = 49/72 (68%), Gaps = 5/72 (6%)
Query: 67 YHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSY-LGRTGINHFRITAVCGDYYI 125
+HGR+ R ++E L A+ +G+YL+RES R+PGS+ L+ G +N +R+ G +++
Sbjct: 7 FHGRISREYADELL--ATAEGAYLIRESQRQPGSHTLALRFGHQTLN-YRL-FYDGKHFV 62
Query: 126 GGRQFDSLTELV 137
G ++F+S+ +LV
Sbjct: 63 GEKRFESVHDLV 74
Score = 37.1 bits (82), Expect = 2.2
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 7/85 (8%)
Query: 236 FHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGG 295
FH ++ E D L+ G++L+R S PG ++L +Q +R+ G ++ +G
Sbjct: 7 FHGRISR-EYADELLATAEGAYLIRESQRQPGSHTLALRFGHQTLNYRLFYDG-KHFVGE 64
Query: 296 RTFECL-----DAVINRYRKEQIVE 315
+ FE + DA+I Y + + E
Sbjct: 65 KRFESVHDLVTDALITLYIETKAAE 89
>UniRef50_Q15464 Cluster: SH2 domain-containing adapter protein B;
n=29; Euteleostomi|Rep: SH2 domain-containing adapter
protein B - Homo sapiens (Human)
Length = 509
Score = 50.4 bits (115), Expect = 2e-04
Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Query: 53 GERQAVLAPPETE-WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGI 111
GER P E + WYHG + R +E L K+ SYLVR S Y LS G
Sbjct: 396 GERVDPAVPLEKQIWYHGAISRGDAENLL-RLCKECSYLVRNSQTSKHDYSLSLRSNQGF 454
Query: 112 NHFRITAVCGDYYIGGRQ--FDSLTELVGFYS 141
H ++ Y +G FDS+ E++ +Y+
Sbjct: 455 MHMKLAKTKEKYVLGQNSPPFDSVPEVIHYYT 486
Score = 44.0 bits (99), Expect = 0.019
Identities = 27/97 (27%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 219 LVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQ 278
L E +DP++ P W+H ++ +A ++L S+LVR S S DYSL N
Sbjct: 395 LGERVDPAV-PLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYSLSLRSNQG 453
Query: 279 IQRFRIEKKGVRYLMGGRT--FECLDAVINRYRKEQI 313
++ K +Y++G + F+ + VI+ Y ++
Sbjct: 454 FMHMKLAKTKEKYVLGQNSPPFDSVPEVIHYYTTRKL 490
>UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38;
Euteleostomi|Rep: Tyrosine-protein kinase ABL2 - Homo
sapiens (Human)
Length = 1182
Score = 50.4 bits (115), Expect = 2e-04
Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDYY 124
WYHG + R ++ E L ++ GS+LVRES+ PG +S + H+RI T G Y
Sbjct: 173 WYHGPVSR-SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVY 231
Query: 125 IGGR-QFDSLTELVGFYSHCSD 145
+ +F +L ELV +S +D
Sbjct: 232 VTAESRFSTLAELVHHHSTVAD 253
Score = 42.7 bits (96), Expect = 0.044
Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
+D VA+ + D + L+ KG+ V +N G+ W QG + +
Sbjct: 107 SDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNQNGE---WSEVRSKNGQGWVPSNYI 162
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H ++S A +L GSFLVR S++SPG S+ ++
Sbjct: 163 TPVN-SLEKH---SWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVY 218
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 219 HYRINTTADGKVYVTAESRFSTLAELVHHH 248
>UniRef50_UPI0000F1D8DB Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 321
Score = 50.0 bits (114), Expect = 3e-04
Identities = 33/93 (35%), Positives = 45/93 (48%), Gaps = 5/93 (5%)
Query: 53 GERQAVLAPPETE-WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGI 111
GER + P E + WYHG L R + E L K+ SYLVR+S Y LS G
Sbjct: 207 GERVDPMLPLEKQVWYHGALTR-SEAESLLTLCKECSYLVRKSQTSRNDYSLSLRSCHGF 265
Query: 112 NHFRITAVCGDYYIGGRQ---FDSLTELVGFYS 141
H + + +I G FDS+ E++ FY+
Sbjct: 266 MHMKFSQSRDGKFILGENSPPFDSIPEVIHFYT 298
Score = 39.5 bits (88), Expect = 0.41
Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 4/98 (4%)
Query: 219 LVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQ 278
L E +DP + P W+H T+SEA +L S+LVR S S DYSL +
Sbjct: 206 LGERVDPML-PLEKQVWYHGALTRSEAESLLTLCKECSYLVRKSQTSRNDYSLSLRSCHG 264
Query: 279 IQRFRI-EKKGVRYLMGGRT--FECLDAVINRYRKEQI 313
+ + + ++++G + F+ + VI+ Y ++
Sbjct: 265 FMHMKFSQSRDGKFILGENSPPFDSIPEVIHFYTTNKL 302
>UniRef50_Q6DEM2 Cluster: V-crk sarcoma virus CT10 oncogene homolog;
n=5; Clupeocephala|Rep: V-crk sarcoma virus CT10
oncogene homolog - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 311
Score = 50.0 bits (114), Expect = 3e-04
Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 27/185 (14%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGD--- 122
WY GRL R + L + G +LVR+S PG YVLS + ++H+ I ++ +
Sbjct: 13 WYWGRLSRQEAVSLL-QGQRHGVFLVRDSITIPGDYVLSVSENSKVSHYIINSISSNRQS 71
Query: 123 --------YYIGGRQFDSLTELVGFYS-HCSDL------LKRERLXXXXXXXXXXN---- 163
+ IG ++FD+L L+ FY H D + + +
Sbjct: 72 GPGLAPPRFRIGDQEFDALPALLEFYKIHYLDTTTLIEPISKSKHSSFISVNAGTGGAPP 131
Query: 164 --DKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVE 221
+++ V A+ + D D L F+KGD+ V + W W + G GMI VE
Sbjct: 132 RLEEEYVRALFDFPGNDDED-LPFRKGDVLRVLEKPEEQW-WNAQNSEGRVGMIPVPYVE 189
Query: 222 DLDPS 226
P+
Sbjct: 190 KYRPA 194
Score = 41.5 bits (93), Expect = 0.10
Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 14/119 (11%)
Query: 234 SWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK------- 286
SW+ ++ EAV +L G FLVR S PGDY L N+++ + I
Sbjct: 12 SWYWGRLSRQEAVSLLQGQRHGVFLVRDSITIPGDYVLSVSENSKVSHYIINSISSNRQS 71
Query: 287 -KGV---RYLMGGRTFECLDAVINRYRKEQIVEGHTLGQPLIAEGHT--IEPQQSTTGA 339
G+ R+ +G + F+ L A++ Y K ++ TL +P+ H+ I T GA
Sbjct: 72 GPGLAPPRFRIGDQEFDALPALLEFY-KIHYLDTTTLIEPISKSKHSSFISVNAGTGGA 129
>UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9;
Endopterygota|Rep: CG3727-PB, isoform B - Drosophila
melanogaster (Fruit fly)
Length = 548
Score = 50.0 bits (114), Expect = 3e-04
Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Query: 234 SWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYL 292
SW++ T+S+ +L G G FL+R S+ + GDYS+ + + FR+ + Y
Sbjct: 447 SWYYGAITRSQCDTVLNGHGHDGDFLIRDSETNMGDYSVSLKAPGRNKHFRVHVEQNMYC 506
Query: 293 MGGRTFECLDAVINRYRKEQI 313
+G R F LD +++ Y++ I
Sbjct: 507 IGQRKFHSLDQLVDHYQRAPI 527
Score = 48.4 bits (110), Expect = 9e-04
Identities = 25/75 (33%), Positives = 36/75 (48%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
WY+G + R + L G +L+R+S+ G Y +S HFR+ Y I
Sbjct: 448 WYYGAITRSQCDTVLNGHGHDGDFLIRDSETNMGDYSVSLKAPGRNKHFRVHVEQNMYCI 507
Query: 126 GGRQFDSLTELVGFY 140
G R+F SL +LV Y
Sbjct: 508 GQRKFHSLDQLVDHY 522
>UniRef50_Q5BWZ4 Cluster: SJCHGC04657 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04657 protein - Schistosoma
japonicum (Blood fluke)
Length = 153
Score = 50.0 bits (114), Expect = 3e-04
Identities = 20/37 (54%), Positives = 27/37 (72%)
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSL 271
WFHP+ T+SEA +++ GSFLVRPS+ P D+SL
Sbjct: 55 WFHPSLTRSEAEELIRNEPEGSFLVRPSETCPNDFSL 91
Score = 37.5 bits (83), Expect = 1.7
Identities = 24/82 (29%), Positives = 44/82 (53%), Gaps = 5/82 (6%)
Query: 63 ETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCG 121
E W+H L R +EE L +GS+LVR S+ P + L+ +T + H +IT G
Sbjct: 52 EQPWFHPSLTRSEAEE-LIRNEPEGSFLVRPSETCPNDFSLTIKHKTFL-HMKITRNNAG 109
Query: 122 DYYIG--GRQFDSLTELVGFYS 141
+ +G + + S+++++ Y+
Sbjct: 110 QFILGEYSQPYSSVSQMIYHYA 131
>UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 983
Score = 50.0 bits (114), Expect = 3e-04
Identities = 29/90 (32%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Query: 52 NGERQAVLAPPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGI 111
N + Q + T + G++DR +E+ S G++LVRES + G Y LS R
Sbjct: 646 NKQNQGLSIRTGTTGFAGKMDRTEAEQETMGRS-DGTFLVRESANRAGEYALSVRFRNAT 704
Query: 112 NHFRITAVCGDYYI-GGRQFDSLTELVGFY 140
H +I G + + + FDS+ ELV +Y
Sbjct: 705 KHIKIPYEDGTFCLTQSKVFDSIPELVAYY 734
Score = 35.9 bits (79), Expect = 5.1
Identities = 27/122 (22%), Positives = 49/122 (40%), Gaps = 1/122 (0%)
Query: 242 KSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIE-KKGVRYLMGGRTFEC 300
++EA + G+FLVR S N G+Y+L N + +I + G L + F+
Sbjct: 667 RTEAEQETMGRSDGTFLVRESANRAGEYALSVRFRNATKHIKIPYEDGTFCLTQSKVFDS 726
Query: 301 LDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQSTTGAAAEKIYATLRECRDQIGLKKT 360
+ ++ YR+ + T + G + G E + T R ++G +
Sbjct: 727 IPELVAYYRENTLGVSFTGLDTTLRCGLNEDQDNREVGWRTEVSWRTEVSWRTEVGWRTE 786
Query: 361 KG 362
G
Sbjct: 787 VG 788
>UniRef50_Q0V6E4 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 1636
Score = 50.0 bits (114), Expect = 3e-04
Identities = 37/136 (27%), Positives = 63/136 (46%), Gaps = 1/136 (0%)
Query: 756 PKPVRYLCGCLQRAAVAKWPNERFVRTRVVSG-FIFLRLICPALVEPRAWTLVQRAPPPH 814
P VRYL + ++P E + V+ G +++ I PAL++P+ W +V R P
Sbjct: 1182 PYGVRYLAQQMFEELRLQFPYEAQEQLLVIVGHWVWKAYIQPALIQPQHWGVVDRGLSPV 1241
Query: 815 AQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPP 874
R+L V K L +A FG ++ Y++ +N +I + +R+ + NV D
Sbjct: 1242 MNRNLGAVNKVLGQVAAGKLFGGEDLYLQPLNSYIAEAIDRVQEIWSNMINVRDAETQFE 1301
Query: 875 NSNVNFEIAKELATLH 890
N A+ TL+
Sbjct: 1302 IDEFNDLFARTKPTLY 1317
>UniRef50_O15357 Cluster: Phosphatidylinositol-3,4,5-trisphosphate
5-phosphatase 2; n=24; Euteleostomi|Rep:
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2
- Homo sapiens (Human)
Length = 1258
Score = 49.6 bits (113), Expect = 4e-04
Identities = 29/83 (34%), Positives = 45/83 (54%), Gaps = 7/83 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-------TA 118
WYH L R +EE L A + GS+LVR+S+ G++ L L + ++ +RI A
Sbjct: 21 WYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCVLYQKHVHTYRILPDGEDFLA 80
Query: 119 VCGDYYIGGRQFDSLTELVGFYS 141
V + R+F +L EL+G Y+
Sbjct: 81 VQTSQGVPVRRFQTLGELIGLYA 103
Score = 41.1 bits (92), Expect = 0.13
Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 234 SWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYL 292
SW+H + +++ A ++L +AG GSFLVR S++ G ++L + +RI G +L
Sbjct: 20 SWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCVLYQKHVHTYRILPDGEDFL 79
>UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5;
Euteleostomi|Rep: Tyrosine-protein kinase BLK - Homo
sapiens (Human)
Length = 505
Score = 49.6 bits (113), Expect = 4e-04
Identities = 48/156 (30%), Positives = 73/156 (46%), Gaps = 14/156 (8%)
Query: 164 DKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDL 223
DK VVA+ YT M D D L KG+ V GD WL + TG +G + V +
Sbjct: 59 DKHFVVALYDYTAMNDRD-LQMLKGEKLQVLKGTGDWWL-ARSLVTGREGYVPSNFVARV 116
Query: 224 DPSIDPNTVFSWFHPNCTKSEAVDMLVKA--GPGSFLVRPSDNSPGDYSLFF-HINNQ-- 278
+ S++ WF + + EA L+ GSFL+R S+ + G +SL + Q
Sbjct: 117 E-SLEMER---WFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTTQGE 172
Query: 279 -IQRFRIE--KKGVRYLMGGRTFECLDAVINRYRKE 311
I+ ++I +G Y+ TF L A++ Y K+
Sbjct: 173 LIKHYKIRCLDEGGYYISPRITFPSLQALVQHYSKK 208
Score = 41.9 bits (94), Expect = 0.077
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 7/87 (8%)
Query: 66 WYHGRLDRYTSEERLWAA-SKQGSYLVRESDRKPGSYVLSYLGRTG----INHFRITAVC 120
W+ R +E +L A +K GS+L+RES+ G++ LS T I H++I +
Sbjct: 124 WFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTTQGELIKHYKIRCLD 183
Query: 121 -GDYYIGGR-QFDSLTELVGFYSHCSD 145
G YYI R F SL LV YS D
Sbjct: 184 EGGYYISPRITFPSLQALVQHYSKKGD 210
>UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG18247-PA - Tribolium castaneum
Length = 725
Score = 49.2 bits (112), Expect = 5e-04
Identities = 23/52 (44%), Positives = 32/52 (61%), Gaps = 1/52 (1%)
Query: 66 WYHGRLDRYTSEERLWAASK-QGSYLVRESDRKPGSYVLSYLGRTGINHFRI 116
WYHG+L R +E L + GS+LVRES+ G +VLS L ++HF+I
Sbjct: 9 WYHGKLSREATENLLKEEGRPDGSFLVRESNSSTGDFVLSVLHNNEVSHFQI 60
Score = 41.1 bits (92), Expect = 0.13
Identities = 26/82 (31%), Positives = 43/82 (52%), Gaps = 3/82 (3%)
Query: 66 WYHGRLDRYTSEERL-WAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
WYHG LDR+ +E + ++K G++LVR SDR VL+ + + ++ I +
Sbjct: 286 WYHGTLDRHEAETTIKQFSTKDGTFLVRWSDRNK-ERVLTLINESLFYNYIIRKQDDYLF 344
Query: 125 I-GGRQFDSLTELVGFYSHCSD 145
I G +SL ++ +YS D
Sbjct: 345 IDNGPYLESLEHIIEYYSFIPD 366
Score = 40.7 bits (91), Expect = 0.18
Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 2/54 (3%)
Query: 235 WFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK 286
W+H ++ ++L + G GSFLVR S++S GD+ L NN++ F+I +
Sbjct: 9 WYHGKLSREATENLLKEEGRPDGSFLVRESNSSTGDFVLSVLHNNEVSHFQIRR 62
>UniRef50_UPI000051A29D Cluster: PREDICTED: similar to SHC-adaptor
protein CG3715-PA; n=2; Apocrita|Rep: PREDICTED: similar
to SHC-adaptor protein CG3715-PA - Apis mellifera
Length = 443
Score = 49.2 bits (112), Expect = 5e-04
Identities = 28/82 (34%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
W+HG + R +E L ++ G +LVRES PG YVL+ + H + G
Sbjct: 346 WFHGSVSRAEAESML---TRDGDFLVRESQGSPGQYVLTGMNNNTPKHLLLIDPEGVVRT 402
Query: 126 GGRQFDSLTELVGFYSHCSDLL 147
R FDS++ LV HC ++L
Sbjct: 403 KDRVFDSVSHLVN--HHCDNVL 422
Score = 41.1 bits (92), Expect = 0.13
Identities = 26/75 (34%), Positives = 39/75 (52%), Gaps = 4/75 (5%)
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQR-FRIEKKGVRYLM 293
WFH + +++EA ML + G FLVR S SPG Y L NN + I+ +GV
Sbjct: 346 WFHGSVSRAEAESMLTR--DGDFLVRESQGSPGQYVLTGMNNNTPKHLLLIDPEGV-VRT 402
Query: 294 GGRTFECLDAVINRY 308
R F+ + ++N +
Sbjct: 403 KDRVFDSVSHLVNHH 417
>UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase
Yes; n=422; root|Rep: Proto-oncogene tyrosine-protein
kinase Yes - Homo sapiens (Human)
Length = 543
Score = 49.2 bits (112), Expect = 5e-04
Identities = 33/89 (37%), Positives = 48/89 (53%), Gaps = 8/89 (8%)
Query: 65 EWYHGRLDRYTSEERLWAASKQ-GSYLVRESDRKPGSYVLSY-----LGRTGINHFRITA 118
EWY G++ R +E L Q G +LVRES+ G+Y LS + + H++I
Sbjct: 157 EWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEIRGDNVKHYKIRK 216
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSD 145
+ G YYI R QFD+L +LV Y+ +D
Sbjct: 217 LDNGGYYITTRAQFDTLQKLVKHYTEHAD 245
Score = 46.0 bits (104), Expect = 0.005
Identities = 37/129 (28%), Positives = 61/129 (47%), Gaps = 7/129 (5%)
Query: 169 VAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
VA+ Y + T++L+F+KG+ F + N+ W + TG+ G I V D SI
Sbjct: 97 VALYDY-EARTTEDLSFKKGERFQIINNTEGDWWEARSIATGKNGYIPSNYVAPAD-SIQ 154
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK 286
W+ + +A +L+ G G FLVR S+ + G YSL ++I+ ++
Sbjct: 155 AE---EWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEIRGDNVKH 211
Query: 287 KGVRYLMGG 295
+R L G
Sbjct: 212 YKIRKLDNG 220
>UniRef50_P08631 Cluster: Tyrosine-protein kinase HCK; n=32;
Euteleostomi|Rep: Tyrosine-protein kinase HCK - Homo
sapiens (Human)
Length = 526
Score = 49.2 bits (112), Expect = 5e-04
Identities = 42/152 (27%), Positives = 71/152 (46%), Gaps = 15/152 (9%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
VVA+ Y + D L+FQKGD V + G+ W + T ++G I V +D S+
Sbjct: 83 VVALYDYEAIHHED-LSFQKGDQMVVLEESGEWWK-ARSLATRKEGYIPSNYVARVD-SL 139
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKAGP--GSFLVRPSDNSPGDYSLFF-----HINNQIQ 280
+ WF ++ +A L+ G GSF++R S+ + G YSL + ++
Sbjct: 140 ETE---EWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVK 196
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRYRK 310
++I G Y+ TF L +++ Y+K
Sbjct: 197 HYKIRTLDNGGFYISPRSTFSTLQELVDHYKK 228
Score = 45.2 bits (102), Expect = 0.008
Identities = 32/89 (35%), Positives = 47/89 (52%), Gaps = 8/89 (8%)
Query: 65 EWYHGRLDRYTSEERLWAASKQ-GSYLVRESDRKPGSYVLS---YLGRTG--INHFRI-T 117
EW+ + R +E +L A GS+++R+S+ GSY LS Y R G + H++I T
Sbjct: 143 EWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRT 202
Query: 118 AVCGDYYIGGRQ-FDSLTELVGFYSHCSD 145
G +YI R F +L ELV Y +D
Sbjct: 203 LDNGGFYISPRSTFSTLQELVDHYKKGND 231
>UniRef50_UPI0000E46C42 Cluster: PREDICTED: similar to Grb14; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
Grb14 - Strongylocentrotus purpuratus
Length = 756
Score = 48.8 bits (111), Expect = 7e-04
Identities = 31/80 (38%), Positives = 43/80 (53%), Gaps = 6/80 (7%)
Query: 66 WYHGRLDRYTSEERLWAASKQ--GSYLVRESDRKPGSYVLSYLGRTGINHFRITAV-CGD 122
W+H L R L+A G +L+RES R PG++VLS+ + H++I V G
Sbjct: 660 WFHSGLTR-DETHALFAKQGMVDGMFLIRESQRIPGAFVLSFSHNQKVKHYQINMVEDGV 718
Query: 123 YYI--GGRQFDSLTELVGFY 140
Y I GG +F L +LV FY
Sbjct: 719 YTIDDGGTRFTDLIQLVEFY 738
Score = 39.9 bits (89), Expect = 0.31
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 5/80 (6%)
Query: 235 WFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIE--KKGVR 290
WFH T+ E + K G G FL+R S PG + L F N +++ ++I + GV
Sbjct: 660 WFHSGLTRDETHALFAKQGMVDGMFLIRESQRIPGAFVLSFSHNQKVKHYQINMVEDGVY 719
Query: 291 YL-MGGRTFECLDAVINRYR 309
+ GG F L ++ Y+
Sbjct: 720 TIDDGGTRFTDLIQLVEFYQ 739
>UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio
"Phospholipase C gamma 1.; n=1; Takifugu rubripes|Rep:
Homolog of Brachydanio rerio "Phospholipase C gamma 1. -
Takifugu rubripes
Length = 1071
Score = 48.8 bits (111), Expect = 7e-04
Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
EWYH L R +E L + G++LVR+ + SY +S+ I H RI +
Sbjct: 618 EWYHSSLSRVQAEHMLMRVPRDGAFLVRKRS-ESHSYAISFRAEGKIKHCRIQQEGRLFM 676
Query: 125 IG-GRQFDSLTELVGFY 140
+G +F+SL +LV +Y
Sbjct: 677 LGSSAEFESLVDLVNYY 693
>UniRef50_Q7M4L6 Cluster: Shb-like adapter protein, Shf; n=21;
Amniota|Rep: Shb-like adapter protein, Shf - Homo
sapiens (Human)
Length = 480
Score = 48.8 bits (111), Expect = 7e-04
Identities = 30/93 (32%), Positives = 44/93 (47%), Gaps = 5/93 (5%)
Query: 53 GERQAVLAPPETE-WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGI 111
GE P E + WYHG + R T E L K+ SYLVR S+ + LS G
Sbjct: 366 GEWTDPALPLENQVWYHGAISR-TDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQGF 424
Query: 112 NHFRITAVCGDYYIGGRQ---FDSLTELVGFYS 141
H +++ + Y+ G+ F S+ E+V Y+
Sbjct: 425 MHMKLSRTKNNKYVLGQNSPPFSSVPEIVHHYA 457
Score = 37.9 bits (84), Expect = 1.3
Identities = 23/98 (23%), Positives = 49/98 (50%), Gaps = 4/98 (4%)
Query: 219 LVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQ 278
L E DP++ P W+H ++++A ++L S+LVR S+ S D+SL +
Sbjct: 365 LGEWTDPAL-PLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQG 423
Query: 279 IQRFRIEK-KGVRYLMGGRT--FECLDAVINRYRKEQI 313
++ + K +Y++G + F + +++ Y ++
Sbjct: 424 FMHMKLSRTKNNKYVLGQNSPPFSSVPEIVHHYASRKL 461
>UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11;
Mammalia|Rep: Tyrosine-protein kinase 6 - Homo sapiens
(Human)
Length = 451
Score = 48.8 bits (111), Expect = 7e-04
Identities = 44/158 (27%), Positives = 70/158 (44%), Gaps = 11/158 (6%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFS--WFHP 238
+EL+F+ GD+F V + W W T E G + + + TV S WF
Sbjct: 25 EELSFRAGDVFHVARKE-EQWWWATL--LDEAGGAVAQGYVPHNYLAERETVESEPWFFG 81
Query: 239 NCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKK--GVRYLMG 294
++SEAV L G G+FL+R S+ DY L ++ ++I ++ G +L
Sbjct: 82 CISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQAVRHYKIWRRAGGRLHLNE 141
Query: 295 GRTFECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEP 332
+F L ++N +R + + G L P H EP
Sbjct: 142 AVSFLSLPELVNYHRAQSLSHGLRLAAP--CRKHEPEP 177
Score = 39.5 bits (88), Expect = 0.41
Identities = 27/90 (30%), Positives = 44/90 (48%), Gaps = 6/90 (6%)
Query: 54 ERQAVLAPPETEWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSYLGRTGIN 112
ER+ V + P W+ G + R + RL A + G++L+R S++ YVLS +
Sbjct: 69 ERETVESEP---WFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQAVR 125
Query: 113 HFRITAVCGD--YYIGGRQFDSLTELVGFY 140
H++I G + F SL ELV ++
Sbjct: 126 HYKIWRRAGGRLHLNEAVSFLSLPELVNYH 155
>UniRef50_UPI0000F1F923 Cluster: PREDICTED: similar to SH2 domain
containing 4B; n=2; Danio rerio|Rep: PREDICTED: similar
to SH2 domain containing 4B - Danio rerio
Length = 266
Score = 48.4 bits (110), Expect = 9e-04
Identities = 32/79 (40%), Positives = 44/79 (55%), Gaps = 7/79 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+HG + R SE L A+ GS+LVR S+R G Y LSY +G HF I A GDYY
Sbjct: 160 WFHGIISREDSETLLMNAAV-GSFLVRVSERIWG-YTLSYRTASGFKHFLIDA-SGDYYS 216
Query: 125 ---IGGRQFDSLTELVGFY 140
+ + +L +L+ F+
Sbjct: 217 FLGVDQNRHATLADLIDFH 235
Score = 41.1 bits (92), Expect = 0.13
Identities = 35/138 (25%), Positives = 61/138 (44%), Gaps = 10/138 (7%)
Query: 199 DGWLWVTAHRTGEQGMIFRELVEDLDPSI-----DPNTVFSWFHPNCTKSEAVDMLVKAG 253
D W+ R G + ++ E+ P + + WFH ++ ++ +L+ A
Sbjct: 119 DSPAWLQTPRPGSRELVILWFNEEQKPKQAGYERNGKAIAPWFHGIISREDSETLLMNAA 178
Query: 254 PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGG--RTFECLDAVINRYRKE 311
GSFLVR S+ G Y+L + + + F I+ G Y G + A + + KE
Sbjct: 179 VGSFLVRVSERIWG-YTLSYRTASGFKHFLIDASGDYYSFLGVDQNRHATLADLIDFHKE 237
Query: 312 QIVEGHTLGQPLIAEGHT 329
+I+ T G+ L+ E T
Sbjct: 238 EIIT--TTGKELLLEACT 253
>UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whole
genome shotgun sequence; n=2; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF13726,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1377
Score = 48.4 bits (110), Expect = 9e-04
Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
EWYH L R +E L + G++LVR+ + SY +S+ I H RI +
Sbjct: 686 EWYHSSLTRVQAEHMLMRVPRDGAFLVRKRS-EHNSYAISFRAEGKIKHCRIQQEGRLFM 744
Query: 125 IG-GRQFDSLTELVGFY 140
+G +F+SL +LV +Y
Sbjct: 745 LGSSAEFESLMDLVSYY 761
Score = 35.1 bits (77), Expect = 8.9
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 14/89 (15%)
Query: 66 WYHGRLD-----RYTSEERLW----AASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI 116
W+HG+L R +E+ L +K G++LVRES+ G Y LS+ + H RI
Sbjct: 570 WFHGKLGGGRDGRQVAEKLLQEYCEGGAKDGTFLVRESETFVGDYTLSFWRSGRVQHCRI 629
Query: 117 -----TAVCGDYYIGGRQFDSLTELVGFY 140
+ Y FDSL L+ Y
Sbjct: 630 HSRQESGSTRFYLTDNLVFDSLYRLICHY 658
>UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 921
Score = 48.4 bits (110), Expect = 9e-04
Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 5/86 (5%)
Query: 56 QAVLAPPETE-WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHF 114
Q V P E + WYHG + R ++ L +K G +LVR+S KPG YVLS HF
Sbjct: 517 QEVERPLEQQTWYHGAIPRLEVQQLL---TKDGDFLVRKSQEKPG-YVLSVHWSGACKHF 572
Query: 115 RITAVCGDYYIGGRQFDSLTELVGFY 140
+ Y + G F ++ +L+ Y
Sbjct: 573 LVQNKDNMYCLDGESFHTIPQLIQQY 598
Score = 47.2 bits (107), Expect = 0.002
Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 6/100 (6%)
Query: 213 GMIFRELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLF 272
G++ + ++++ ++ T W+H + E +L K G FLVR S PG Y L
Sbjct: 509 GLVLSPVGQEVERPLEQQT---WYHGAIPRLEVQQLLTK--DGDFLVRKSQEKPG-YVLS 562
Query: 273 FHINNQIQRFRIEKKGVRYLMGGRTFECLDAVINRYRKEQ 312
H + + F ++ K Y + G +F + +I +Y+ Q
Sbjct: 563 VHWSGACKHFLVQNKDNMYCLDGESFHTIPQLIQQYQTSQ 602
>UniRef50_Q8WPV5 Cluster: Tyrosine kinase; n=2; Eumetazoa|Rep:
Tyrosine kinase - Schistosoma mansoni (Blood fluke)
Length = 1264
Score = 48.4 bits (110), Expect = 9e-04
Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 3/82 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQ-GSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
WYH + RY +E RL + Q G++LVR ++ +YVLS + H+RI +
Sbjct: 202 WYHHTIRRYEAESRLASEGNQDGAFLVRYR-KEDRTYVLSLTSQNEPKHYRIEEYLSRWS 260
Query: 125 I-GGRQFDSLTELVGFYSHCSD 145
I GG+ F+++ EL+ Y D
Sbjct: 261 IEGGQYFETIMELIDHYHFRQD 282
Score = 37.1 bits (82), Expect = 2.2
Identities = 25/85 (29%), Positives = 46/85 (54%), Gaps = 6/85 (7%)
Query: 61 PPE-TEWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRIT- 117
PPE T +++G++ R +EE L+ + +G +L+RES + + + +LGR ++H+ +
Sbjct: 43 PPESTNYFYGKITREQAEELLFTNGANEGLFLLRESVNRNYAVSICHLGR--VHHYNVER 100
Query: 118 -AVCGDYYIGGRQFDSLTELVGFYS 141
C G +F ELV +S
Sbjct: 101 HTDCSYRIQTGHKFIGPVELVQHHS 125
>UniRef50_Q13576 Cluster: Ras GTPase-activating-like protein IQGAP2;
n=24; Euteleostomi|Rep: Ras GTPase-activating-like
protein IQGAP2 - Homo sapiens (Human)
Length = 1575
Score = 48.4 bits (110), Expect = 9e-04
Identities = 32/140 (22%), Positives = 67/140 (47%), Gaps = 5/140 (3%)
Query: 735 EFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPN-ERFVRTRVVSGFIFLRL 793
E L + D++ SI +S + P +RY+ L+ + K+P+ ++V ++ R
Sbjct: 1049 ENLRRVTDKVLNSIISSLDLLPYGLRYIAKVLKNSIHEKFPDATEDELLKIVGNLLYYRY 1108
Query: 794 ICPALVEPRAWTLVQRAP----PPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFI 849
+ PA+V P + ++ +R+L VAK LQ+ A+ F + ++ +N ++
Sbjct: 1109 MNPAIVAPDGFDIIDMTAGGQINSDQRRNLGSVAKVLQHAASNKLFEGENEHLSSMNNYL 1168
Query: 850 LKNKERMVVFLDQLSNVPDP 869
+ + + + NVP+P
Sbjct: 1169 SETYQEFRKYFKEACNVPEP 1188
>UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosine
kinase CG4032-PA; n=1; Apis mellifera|Rep: PREDICTED:
similar to Abl tyrosine kinase CG4032-PA - Apis
mellifera
Length = 1439
Score = 48.0 bits (109), Expect = 0.001
Identities = 33/84 (39%), Positives = 48/84 (57%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRITAVC-GD 122
WYHGR+ R + E L ++ GS+LVRES+ PG S L Y GR + H+RI G
Sbjct: 174 WYHGRICR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINEDSEGK 230
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
++ +F++L ELV +S +D
Sbjct: 231 MFVTTESKFNTLAELVHHHSMLAD 254
Score = 46.0 bits (104), Expect = 0.005
Identities = 34/133 (25%), Positives = 67/133 (50%), Gaps = 12/133 (9%)
Query: 181 DELTFQKGDIFFV--HNDMGDGWLWVTAHR-TGEQGMIFRELVEDLDPSIDPNTVFSWFH 237
++L+ +KG+ + +N G+ W AH TG+ G + V ++ S++ + SW+H
Sbjct: 124 NQLSLKKGEQVRILSYNKSGE---WCEAHSSTGQVGWVPSNYVTPVN-SLEKH---SWYH 176
Query: 238 PNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGG 295
++ A +L GSFLVR S++SPG S+ ++ +RI + +G ++
Sbjct: 177 GRICRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDSEGKMFVTTE 236
Query: 296 RTFECLDAVINRY 308
F L +++ +
Sbjct: 237 SKFNTLAELVHHH 249
>UniRef50_UPI000069F318 Cluster: UPI000069F318 related cluster; n=1;
Xenopus tropicalis|Rep: UPI000069F318 UniRef100 entry -
Xenopus tropicalis
Length = 402
Score = 48.0 bits (109), Expect = 0.001
Identities = 63/276 (22%), Positives = 122/276 (44%), Gaps = 26/276 (9%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
+H S+ + +CF+++ S+ F A ++ E WIE LR + P + + +
Sbjct: 147 LHSSILGERYCFEIITAE----SSRCF-ACSSLQERDRWIENLRRIVQPDKDNFERQESS 201
Query: 481 VSWVLWLR-VRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDPHWXXXXXXXXMP 539
+S LW+ + L +R V L RT + +P+ +
Sbjct: 202 LS--LWIHEAKGLPVSGPGSRSCY--FCEVQLDGCLYGRTSSK-APEAGVVFWGESFNLR 256
Query: 540 PDVTSLT--ITVHNTGKRGKESE-VAELTIELANLANGEEIEEWYPLVGMTPIGEWGSLR 596
D++S+ + +H + GKE+ V +T+ L + +G E +W PL G +LR
Sbjct: 257 -DLSSVQGHMALHLL-QEGKETTGVGTVTLALEGMKDGAE--KWVPLGGEM------ALR 306
Query: 597 LRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALAD-LCRTDRQPLATSVLNTFAECGRG 655
+R RY + V+P +Y + L + +A+ L +++ L S++ G+
Sbjct: 307 VRGRYRKLSVLPVMQYKEFAEYLTWRYMELSRAMEPILSAREKEELGRSLVYVLQSTGKA 366
Query: 656 AELARELTCAEVAR-EGDHKTLFRGASLATAVLDEF 690
E +L AE++R +G +FR ++ T ++E+
Sbjct: 367 KEFLVDLGVAEISRHDGQDSLIFRENTIVTKAIEEY 402
>UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2;
Culicidae|Rep: Tyrosine-protein kinase - Aedes aegypti
(Yellowfever mosquito)
Length = 747
Score = 48.0 bits (109), Expect = 0.001
Identities = 21/51 (41%), Positives = 30/51 (58%)
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIE 285
WFH + EA ++L G FLVR S N PGDY+L N +++ +RI+
Sbjct: 378 WFHGRIKREEAENLLKPREDGLFLVRESTNFPGDYTLCVCFNEKVEHYRIK 428
Score = 47.6 bits (108), Expect = 0.002
Identities = 29/81 (35%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
W+HGR+ R +E L + G +LVRES PG Y L + H+RI I
Sbjct: 378 WFHGRIKREEAENLL-KPREDGLFLVRESTNFPGDYTLCVCFNEKVEHYRIKYAENKLTI 436
Query: 126 GGRQ-FDSLTELVGFYSHCSD 145
+ FD+L +LV Y+ SD
Sbjct: 437 DDDEYFDNLGQLVEHYTLDSD 457
>UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17;
Amniota|Rep: Tyrosine-protein kinase Srms - Homo sapiens
(Human)
Length = 488
Score = 48.0 bits (109), Expect = 0.001
Identities = 27/96 (28%), Positives = 50/96 (52%), Gaps = 4/96 (4%)
Query: 235 WFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIE--KKGVR 290
W+ ++++A +L+ PG+FL+RPS++S G YSL ++ +R+ G
Sbjct: 120 WYFSGVSRTQAQQLLLSPPNEPGAFLIRPSESSLGGYSLSVRAQAKVCHYRVSMAADGSL 179
Query: 291 YLMGGRTFECLDAVINRYRKEQIVEGHTLGQPLIAE 326
YL GR F L+ ++ Y+ + + L QP + +
Sbjct: 180 YLQKGRLFPGLEELLTYYKANWKLIQNPLLQPCMPQ 215
Score = 44.0 bits (99), Expect = 0.019
Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 7/88 (7%)
Query: 60 APPET----EWYHGRLDRYTSEERLWAASKQ-GSYLVRESDRKPGSYVLSYLGRTGINHF 114
A PET WY + R +++ L + + G++L+R S+ G Y LS + + H+
Sbjct: 110 ASPETLSDQPWYFSGVSRTQAQQLLLSPPNEPGAFLIRPSESSLGGYSLSVRAQAKVCHY 169
Query: 115 RIT-AVCGDYYI-GGRQFDSLTELVGFY 140
R++ A G Y+ GR F L EL+ +Y
Sbjct: 170 RVSMAADGSLYLQKGRLFPGLEELLTYY 197
>UniRef50_Q9H788 Cluster: SH2 domain-containing protein 4A (Protein
SH(2)A); n=23; Euteleostomi|Rep: SH2 domain-containing
protein 4A (Protein SH(2)A) - Homo sapiens (Human)
Length = 454
Score = 48.0 bits (109), Expect = 0.001
Identities = 29/78 (37%), Positives = 41/78 (52%), Gaps = 4/78 (5%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDY-Y 124
W+HG L + E L + GS+L+R S+R G Y LSYL G HF I A Y +
Sbjct: 347 WFHGILTLKKANELLLSTGMPGSFLIRVSERIKG-YALSYLSEDGCKHFLIDASADAYSF 405
Query: 125 IGGRQFD--SLTELVGFY 140
+G Q +L +LV ++
Sbjct: 406 LGVDQLQHATLADLVEYH 423
Score = 38.3 bits (85), Expect = 0.95
Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 6/98 (6%)
Query: 230 NTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKG 288
+T+ WFH T +A ++L+ G PGSFL+R S+ G Y+L + + + F I+
Sbjct: 342 DTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKG-YALSYLSEDGCKHFLIDASA 400
Query: 289 VRYLMGG--RTFECLDAVINRYRKEQIVEGHTLGQPLI 324
Y G + A + Y KE+ + +LG+ L+
Sbjct: 401 DAYSFLGVDQLQHATLADLVEYHKEEPIT--SLGKELL 436
>UniRef50_UPI0000E48B80 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 936
Score = 47.6 bits (108), Expect = 0.002
Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDYY 124
WY+GR+ R E + + K YLVR+S + G +LS L + ++H+ I T +
Sbjct: 836 WYYGRMLRQECEYLMLSQGKSKQYLVRDSSHRAGDLMLSVLYGSKVHHYVIQTTDDKKFQ 895
Query: 125 IGGRQFDSLTELVGFY 140
I FDS+ ++ FY
Sbjct: 896 IAHHDFDSVEAILDFY 911
>UniRef50_UPI00004995F7 Cluster: Ras GTPase activating protein; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: Ras GTPase
activating protein - Entamoeba histolytica HM-1:IMSS
Length = 1177
Score = 47.6 bits (108), Expect = 0.002
Identities = 52/235 (22%), Positives = 99/235 (42%), Gaps = 8/235 (3%)
Query: 635 RTDRQPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAH 694
R + LA +VLN + ++ E D +LFR + AT V F+
Sbjct: 229 RDKAEELADAVLNLTYSKRLALDFVSQMLKEEFETHTDSHSLFRENTSATRVAKSFLAKV 288
Query: 695 CKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEA 754
+ +L +Q++I S + E++ + + N + L ++ + S +
Sbjct: 289 GRKYLLDIYKPFVQEIIHSDISFEIDDHRETDKEKLETNKQNLFEACRKLFDLVIDSFDL 348
Query: 755 CPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQ--RAPP 812
+ + AA R + FI LR I PA+ P + +V +
Sbjct: 349 LLLEIFN-----EYAAQFFGELSDDSRNSLTGSFIMLRYINPAIFSPEKYGIVDDPKEIS 403
Query: 813 PHAQRSLLMVAKCLQNLANLVEF-GAKEPYMEVVNPFILKNKERMVVFLDQLSNV 866
+R+L++++K LQNL+N V+F KEP+M +N + + ++ + ++ NV
Sbjct: 404 MSGRRNLILLSKVLQNLSNGVKFIQEKEPFMLPLNVILDEYLDKFKRYFRRIVNV 458
>UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP09923p
- Drosophila melanogaster (Fruit fly)
Length = 847
Score = 47.6 bits (108), Expect = 0.002
Identities = 20/51 (39%), Positives = 31/51 (60%)
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIE 285
WFH + T+ EA +L G FLVR S N PGDY+L ++++ +R++
Sbjct: 479 WFHGSITRDEAEHLLQPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVK 529
Score = 45.2 bits (102), Expect = 0.008
Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
W+HG + R E L + G +LVRES PG Y L ++ + H+R+ + I
Sbjct: 479 WFHGSITR-DEAEHLLQPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLENKLTI 537
Query: 126 GGRQ-FDSLTELVGFYSHCSD 145
+ F++L +LV Y +D
Sbjct: 538 DDEEYFENLGQLVAHYEADAD 558
>UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase
LCK; n=11; Coelomata|Rep: Proto-oncogene
tyrosine-protein kinase LCK - Homo sapiens (Human)
Length = 516
Score = 47.6 bits (108), Expect = 0.002
Identities = 44/160 (27%), Positives = 74/160 (46%), Gaps = 17/160 (10%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
V+A+ Y D D L F+KG+ + G+ W + TG++G I V + S+
Sbjct: 124 VIALHSYEPSHDGD-LGFEKGEQLRILEQSGEWWK-AQSLTTGQEGFIPFNFVAKAN-SL 180
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKAGP--GSFLVRPSDNSPGDYSLFFHINNQ-----IQ 280
+P WF N ++ +A L+ G GSFL+R S+++ G +SL +Q ++
Sbjct: 181 EPEP---WFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVK 237
Query: 281 RFRIEK--KGVRYLMGGRTFECLDAVINRYRKEQIVEGHT 318
++I G Y+ TF L ++ Y + GHT
Sbjct: 238 HYKIRNLDNGGFYISPRITFPGLHELVRHYTR--YYNGHT 275
Score = 37.9 bits (84), Expect = 1.3
Identities = 29/84 (34%), Positives = 44/84 (52%), Gaps = 8/84 (9%)
Query: 66 WYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLS---YLGRTG--INHFRITAV 119
W+ L R +E +L A + GS+L+RES+ GS+ LS + G + H++I +
Sbjct: 185 WFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNL 244
Query: 120 -CGDYYIGGR-QFDSLTELVGFYS 141
G +YI R F L ELV Y+
Sbjct: 245 DNGGFYISPRITFPGLHELVRHYT 268
>UniRef50_O14492 Cluster: SH2B adapter protein 2; n=7;
Tetrapoda|Rep: SH2B adapter protein 2 - Homo sapiens
(Human)
Length = 632
Score = 47.6 bits (108), Expect = 0.002
Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 7/86 (8%)
Query: 206 AHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGP---GSFLVRPS 262
++ TGEQG E + +P ++ + + WFH ++ +A +++ GP G F++R S
Sbjct: 392 SNNTGEQGA---ETDPEAEPELELSD-YPWFHGTLSRVKAAQLVLAGGPRNHGLFVIRQS 447
Query: 263 DNSPGDYSLFFHINNQIQRFRIEKKG 288
+ PG+Y L F+ + + R+ G
Sbjct: 448 ETRPGEYVLTFNFQGKAKHLRLSLNG 473
Score = 41.9 bits (94), Expect = 0.077
Identities = 24/96 (25%), Positives = 51/96 (53%), Gaps = 4/96 (4%)
Query: 51 TNGERQAVLAPPETEWYHGRLDRYTSEERLWAASKQ--GSYLVRESDRKPGSYVLSYLGR 108
T+ E + L + W+HG L R + + + A + G +++R+S+ +PG YVL++ +
Sbjct: 402 TDPEAEPELELSDYPWFHGTLSRVKAAQLVLAGGPRNHGLFVIRQSETRPGEYVLTFNFQ 461
Query: 109 TGINHFRITA-VCGDYYIGGRQFDSLTELV-GFYSH 142
H R++ G ++ F S+ +++ F++H
Sbjct: 462 GKAKHLRLSLNGHGQCHVQHLWFQSVLDMLRHFHTH 497
>UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5;
Eumetazoa|Rep: Tyrosine-protein kinase Abl - Drosophila
melanogaster (Fruit fly)
Length = 1620
Score = 47.6 bits (108), Expect = 0.002
Identities = 40/149 (26%), Positives = 73/149 (48%), Gaps = 14/149 (9%)
Query: 181 DELTFQKGDIFFV--HNDMGDGWLWVTAHR-TGEQGMIFRELVEDLDPSIDPNTVFSWFH 237
++L+ +KG+ + +N G+ W AH +G G + V L+ S++ + SW+H
Sbjct: 204 NQLSLKKGEQVRILSYNKSGE---WCEAHSDSGNVGWVPSNYVTPLN-SLEKH---SWYH 256
Query: 238 PNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGG 295
+++ A +L GSFLVR S++SPG S+ ++ +RI + G ++
Sbjct: 257 GPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRISEDPDGKVFVTQE 316
Query: 296 RTFECLDAVINRYRKEQIVEGHTLGQPLI 324
F L +++ + EGH L PL+
Sbjct: 317 AKFNTLAELVHHHSVPH--EGHGLITPLL 343
Score = 44.8 bits (101), Expect = 0.011
Identities = 31/80 (38%), Positives = 46/80 (57%), Gaps = 7/80 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRITA-VCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI+ G
Sbjct: 254 WYHGPISR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRISEDPDGK 310
Query: 123 YYIGGR-QFDSLTELVGFYS 141
++ +F++L ELV +S
Sbjct: 311 VFVTQEAKFNTLAELVHHHS 330
>UniRef50_A2AQ87 Cluster: Novel protein (Possible orthologue of
human Src homology 2 domain containing F (SHF)); n=10;
Euteleostomi|Rep: Novel protein (Possible orthologue of
human Src homology 2 domain containing F (SHF)) - Mus
musculus (Mouse)
Length = 446
Score = 47.2 bits (107), Expect = 0.002
Identities = 30/93 (32%), Positives = 43/93 (46%), Gaps = 5/93 (5%)
Query: 53 GERQAVLAPPETE-WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGI 111
GE P E + WYHG + R T E L K+ SYLVR S+ + LS G
Sbjct: 332 GEWTDPALPLENQVWYHGAISR-TDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQGF 390
Query: 112 NHFRITAVCGDYYIGGRQ---FDSLTELVGFYS 141
H +++ Y+ G+ F S+ E+V Y+
Sbjct: 391 MHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYA 423
Score = 37.1 bits (82), Expect = 2.2
Identities = 23/98 (23%), Positives = 49/98 (50%), Gaps = 4/98 (4%)
Query: 219 LVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQ 278
L E DP++ P W+H ++++A ++L S+LVR S+ S D+SL +
Sbjct: 331 LGEWTDPAL-PLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQG 389
Query: 279 IQRFRIEK-KGVRYLMGGRT--FECLDAVINRYRKEQI 313
++ + K +Y++G + F + +++ Y ++
Sbjct: 390 FMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKL 427
>UniRef50_Q22070 Cluster: Putative uncharacterized protein plc-3;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein plc-3 - Caenorhabditis elegans
Length = 1299
Score = 47.2 bits (107), Expect = 0.002
Identities = 24/100 (24%), Positives = 48/100 (48%), Gaps = 1/100 (1%)
Query: 225 PSIDPNTVFSWFHPNCTKSEAVDML-VKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFR 283
P P+ WF K +A ++L + G+FL+R S Y L ++ + +R
Sbjct: 654 PQPQPHLNQPWFSATADKEKAEELLSLVPEDGAFLIRTSSTDSSVYVLSLKVDGEFWHYR 713
Query: 284 IEKKGVRYLMGGRTFECLDAVINRYRKEQIVEGHTLGQPL 323
+++ G +++ + FE L+ ++ Y + V G +L P+
Sbjct: 714 LKRDGRIFVVNQKVFENLNQIVEFYANREFVRGISLRFPV 753
Score = 46.0 bits (104), Expect = 0.005
Identities = 25/84 (29%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGS--YLVRESDRKPGSYVLSYLGRTGINHFRITAVCGD 122
EW+HGR +R +++R+ ++G+ +++R+S+ G + LS L ++H RI + D
Sbjct: 553 EWFHGRCERDEAKKRILEHKEKGNGLFMIRDSNLFIGDFSLSILHDGKVHHVRIRSKIID 612
Query: 123 -----YYIGGRQFDSLTELVGFYS 141
Y++ + D+L ELV +Y+
Sbjct: 613 KEKKYYFMDNKVCDTLYELVSYYT 636
Score = 40.3 bits (90), Expect = 0.24
Identities = 20/77 (25%), Positives = 38/77 (49%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
W+ D+ +EE L + G++L+R S YVLS H+R+ + +
Sbjct: 664 WFSATADKEKAEELLSLVPEDGAFLIRTSSTDSSVYVLSLKVDGEFWHYRLKRDGRIFVV 723
Query: 126 GGRQFDSLTELVGFYSH 142
+ F++L ++V FY++
Sbjct: 724 NQKVFENLNQIVEFYAN 740
Score = 39.5 bits (88), Expect = 0.41
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 8/91 (8%)
Query: 235 WFHPNCTKSEAVDMLVK---AGPGSFLVRPSDNSPGDYSLFFHINNQIQRFR-----IEK 286
WFH C + EA +++ G G F++R S+ GD+SL + ++ R I+K
Sbjct: 554 WFHGRCERDEAKKRILEHKEKGNGLFMIRDSNLFIGDFSLSILHDGKVHHVRIRSKIIDK 613
Query: 287 KGVRYLMGGRTFECLDAVINRYRKEQIVEGH 317
+ Y M + + L +++ Y + + H
Sbjct: 614 EKKYYFMDNKVCDTLYELVSYYTRHYLTTAH 644
>UniRef50_Q9UKW4 Cluster: Protein vav-3; n=96; Euteleostomi|Rep:
Protein vav-3 - Homo sapiens (Human)
Length = 847
Score = 47.2 bits (107), Expect = 0.002
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
WY G ++R +E L +YLVR ++ G Y +S H +I G ++I
Sbjct: 672 WYAGAMERLQAETEL-INRVNSTYLVRHRTKESGEYAISIKYNNEAKHIKILTRDGFFHI 730
Query: 126 G-GRQFDSLTELVGFYSHCS 144
R+F SL ELV +Y H S
Sbjct: 731 AENRKFKSLMELVEYYKHHS 750
Score = 35.1 bits (77), Expect = 8.9
Identities = 18/83 (21%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI-EKKGVRYLM 293
W+ + +A L+ ++LVR G+Y++ NN+ + +I + G ++
Sbjct: 672 WYAGAMERLQAETELINRVNSTYLVRHRTKESGEYAISIKYNNEAKHIKILTRDGFFHIA 731
Query: 294 GGRTFECLDAVINRYRKEQIVEG 316
R F+ L ++ Y+ + EG
Sbjct: 732 ENRKFKSLMELVEYYKHHSLKEG 754
>UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2;
Sophophora|Rep: Tyrosine-protein kinase shark -
Drosophila melanogaster (Fruit fly)
Length = 939
Score = 47.2 bits (107), Expect = 0.002
Identities = 20/52 (38%), Positives = 32/52 (61%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI 116
+WYHG L R ++E L + G++LVRES G +VLS L + + H+++
Sbjct: 9 KWYHGNLSREAADELLKQGYEDGTFLVRESSTAAGDFVLSLLCQGEVCHYQV 60
Score = 39.1 bits (87), Expect = 0.54
Identities = 19/56 (33%), Positives = 32/56 (57%), Gaps = 3/56 (5%)
Query: 235 WFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKG 288
W+H N ++ EA D L+K G G+FLVR S + GD+ L ++ +++ + G
Sbjct: 10 WYHGNLSR-EAADELLKQGYEDGTFLVRESSTAAGDFVLSLLCQGEVCHYQVRRHG 64
>UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hydra
vulgaris|Rep: Tyrosine-protein kinase HTK16 - Hydra
attenuata (Hydra) (Hydra vulgaris)
Length = 757
Score = 47.2 bits (107), Expect = 0.002
Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 3/83 (3%)
Query: 66 WYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
WYHG++ R + + L + G +L+R+ P YVLS + R+ I HF+I + + +
Sbjct: 10 WYHGKITREVAVQVLLRKGGRDGFFLIRDCGNAPEDYVLSMMFRSQILHFQINCLGDNKF 69
Query: 125 I--GGRQFDSLTELVGFYSHCSD 145
G F L L+ +Y SD
Sbjct: 70 SIDNGPIFQGLDMLISYYKVISD 92
Score = 46.0 bits (104), Expect = 0.005
Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 4/79 (5%)
Query: 235 WFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVR-- 290
W+H T+ AV +L++ G G FL+R N+P DY L +QI F+I G
Sbjct: 10 WYHGKITREVAVQVLLRKGGRDGFFLIRDCGNAPEDYVLSMMFRSQILHFQINCLGDNKF 69
Query: 291 YLMGGRTFECLDAVINRYR 309
+ G F+ LD +I+ Y+
Sbjct: 70 SIDNGPIFQGLDMLISYYK 88
Score = 40.7 bits (91), Expect = 0.18
Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 3/85 (3%)
Query: 64 TEWYHGRLDRYTSEERLWAASK-QGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGD 122
T+W H LDR + L AS GS+L+R S + G YVL+ + HF+I +
Sbjct: 285 TQWLHQNLDRNGALIILQNASMADGSFLIRSSIKCHGYYVLTLVYEKKTYHFQIKSRADR 344
Query: 123 -YYI-GGRQFDSLTELVGFYSHCSD 145
+YI G F++L LV Y +D
Sbjct: 345 WFYIDDGPLFETLPHLVDHYMQYAD 369
Score = 38.7 bits (86), Expect = 0.72
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 5/89 (5%)
Query: 225 PSIDPNT-VFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINNQIQR 281
P P T + W H N ++ A+ +L A GSFL+R S G Y L +
Sbjct: 276 PVNQPKTSITQWLHQNLDRNGALIILQNASMADGSFLIRSSIKCHGYYVLTLVYEKKTYH 335
Query: 282 FRIEKKGVR--YLMGGRTFECLDAVINRY 308
F+I+ + R Y+ G FE L +++ Y
Sbjct: 336 FQIKSRADRWFYIDDGPLFETLPHLVDHY 364
>UniRef50_Q1ED32 Cluster: Zgc:136231; n=1; Danio rerio|Rep:
Zgc:136231 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 222
Score = 46.8 bits (106), Expect = 0.003
Identities = 32/84 (38%), Positives = 46/84 (54%), Gaps = 8/84 (9%)
Query: 66 WYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSYLGRTG-----INHFRITAV 119
W+ ++R +E L A +K GS+LVRES+ G++ LS T + H++I A+
Sbjct: 104 WFFKDMNRRDTERLLLAPGNKPGSFLVRESETTKGAFSLSIRDSTPEQGDVVKHYKIRAL 163
Query: 120 -CGDYYIG-GRQFDSLTELVGFYS 141
G YYI F SL ELV +YS
Sbjct: 164 DNGGYYISPSTSFSSLQELVKYYS 187
Score = 44.4 bits (100), Expect = 0.014
Identities = 41/159 (25%), Positives = 68/159 (42%), Gaps = 15/159 (9%)
Query: 163 NDKKRVVAILPYTKMPDTD-ELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVE 221
N++ V I Y P ++ +L F+KGD + + G+ WL + TG +G I V
Sbjct: 36 NNQDEDVVIAQYDFQPASENDLQFKKGDRLRIIKENGEWWL-AKSLVTGYEGFIPSTYVA 94
Query: 222 DLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINNQI 279
V WF + + + +L+ G PGSFLVR S+ + G +SL +
Sbjct: 95 RAQTL----QVERWFFKDMNRRDTERLLLAPGNKPGSFLVRESETTKGAFSLSIRDSTPE 150
Query: 280 Q-------RFRIEKKGVRYLMGGRTFECLDAVINRYRKE 311
Q + R G Y+ +F L ++ Y ++
Sbjct: 151 QGDVVKHYKIRALDNGGYYISPSTSFSSLQELVKYYSRK 189
>UniRef50_Q9TYT3 Cluster: Putative uncharacterized protein; n=5;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 46.8 bits (106), Expect = 0.003
Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 8/78 (10%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDY-- 123
WYHG L R ++ L +G +LVR+SD PG YVLS GRT N + + ++
Sbjct: 211 WYHGNLSREDAQALL---KTEGDFLVRQSDHTPGKYVLS--GRTAENEHKHLILLDNHNR 265
Query: 124 -YIGGRQFDSLTELVGFY 140
R F +++EL+ ++
Sbjct: 266 VRTRDRTFSNISELIDYH 283
Score = 35.1 bits (77), Expect = 8.9
Identities = 17/37 (45%), Positives = 24/37 (64%), Gaps = 2/37 (5%)
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSL 271
W+H N ++ +A L+K G FLVR SD++PG Y L
Sbjct: 211 WYHGNLSREDA-QALLKT-EGDFLVRQSDHTPGKYVL 245
>UniRef50_UPI00015B496D Cluster: PREDICTED: similar to conserved
hypothetical protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to conserved hypothetical protein -
Nasonia vitripennis
Length = 1182
Score = 46.4 bits (105), Expect = 0.004
Identities = 29/80 (36%), Positives = 39/80 (48%), Gaps = 5/80 (6%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI--TAVCGDY 123
WYHG + R +E L ++GSYLVR S+ Y LS G H RI Y
Sbjct: 1081 WYHGSITRIEAEAVL-RLLREGSYLVRNSESTKQDYSLSLKSARGFMHMRIQKNEELNAY 1139
Query: 124 YIG--GRQFDSLTELVGFYS 141
+G + FDS+ E+V +S
Sbjct: 1140 ILGQFSKPFDSIPEMVRHFS 1159
Score = 37.9 bits (84), Expect = 1.3
Identities = 22/78 (28%), Positives = 39/78 (50%), Gaps = 4/78 (5%)
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV--RYL 292
W+H + T+ EA +L GS+LVR S+++ DYSL RI+K Y+
Sbjct: 1081 WYHGSITRIEAEAVLRLLREGSYLVRNSESTKQDYSLSLKSARGFMHMRIQKNEELNAYI 1140
Query: 293 MG--GRTFECLDAVINRY 308
+G + F+ + ++ +
Sbjct: 1141 LGQFSKPFDSIPEMVRHF 1158
>UniRef50_UPI0000DB713D Cluster: PREDICTED: similar to CG11146-PA
isoform 2; n=1; Apis mellifera|Rep: PREDICTED: similar to
CG11146-PA isoform 2 - Apis mellifera
Length = 1122
Score = 46.4 bits (105), Expect = 0.004
Identities = 29/80 (36%), Positives = 39/80 (48%), Gaps = 5/80 (6%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI--TAVCGDY 123
WYHG + R +E L ++GSYLVR S+ Y LS G H RI Y
Sbjct: 1021 WYHGSITRIEAEAVL-RLLREGSYLVRNSESTKQDYSLSLKSARGFMHMRIQKNEELNAY 1079
Query: 124 YIG--GRQFDSLTELVGFYS 141
+G + FDS+ E+V +S
Sbjct: 1080 ILGQFSKPFDSIPEMVRHFS 1099
Score = 38.3 bits (85), Expect = 0.95
Identities = 27/100 (27%), Positives = 48/100 (48%), Gaps = 8/100 (8%)
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV--RYL 292
W+H + T+ EA +L GS+LVR S+++ DYSL RI+K Y+
Sbjct: 1021 WYHGSITRIEAEAVLRLLREGSYLVRNSESTKQDYSLSLKSARGFMHMRIQKNEELNAYI 1080
Query: 293 MG--GRTFECLDAVINRYRKEQI----VEGHTLGQPLIAE 326
+G + F+ + ++ + ++ E L P+IA+
Sbjct: 1081 LGQFSKPFDSIPEMVRHFSVNRLPIRGAEHMCLLHPVIAQ 1120
>UniRef50_A1L2D2 Cluster: Zgc:158798; n=7; Clupeocephala|Rep:
Zgc:158798 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 391
Score = 46.4 bits (105), Expect = 0.004
Identities = 31/93 (33%), Positives = 45/93 (48%), Gaps = 5/93 (5%)
Query: 53 GERQAVLAPPETE-WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGI 111
GER P E + WYHG L R + E L K+ SYLVR S+ Y LS G
Sbjct: 277 GERVDPSLPLEKQVWYHGSLSR-SEAESLLTLCKECSYLVRNSETSRLDYSLSLRSCQGF 335
Query: 112 NHFRITAVCGDYYIGGRQ---FDSLTELVGFYS 141
H + + YI G+ F+++ E++ +Y+
Sbjct: 336 MHMKFSQCKDGRYILGQNSPPFETIPEVIHYYT 368
Score = 44.4 bits (100), Expect = 0.014
Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
E +DPS+ P W+H + ++SEA +L S+LVR S+ S DYSL
Sbjct: 278 ERVDPSL-PLEKQVWYHGSLSRSEAESLLTLCKECSYLVRNSETSRLDYSLSLRSCQGFM 336
Query: 281 RFRIEK-KGVRYLMGGRT--FECLDAVINRYRKEQI 313
+ + K RY++G + FE + VI+ Y ++
Sbjct: 337 HMKFSQCKDGRYILGQNSPPFETIPEVIHYYTTHKL 372
>UniRef50_Q9VYM1 Cluster: CG11146-PA; n=2; Coelomata|Rep: CG11146-PA -
Drosophila melanogaster (Fruit fly)
Length = 1416
Score = 46.4 bits (105), Expect = 0.004
Identities = 30/84 (35%), Positives = 42/84 (50%), Gaps = 5/84 (5%)
Query: 58 VLAPPETE-WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI 116
V P E + WYHG + R +E L S +GS+LVR + Y LS G G H RI
Sbjct: 1307 VTIPLERQGWYHGAITRIEAETTLRPLS-EGSFLVRNCESTKQDYSLSLKGAKGFMHMRI 1365
Query: 117 TA-VCGDYYIG--GRQFDSLTELV 137
G Y +G R F+++ E++
Sbjct: 1366 QRNETGQYILGQFSRPFETVPEMI 1389
Score = 39.9 bits (89), Expect = 0.31
Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 7/99 (7%)
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV-RYLM 293
W+H T+ EA L GSFLVR +++ DYSL RI++ +Y++
Sbjct: 1316 WYHGAITRIEAETTLRPLSEGSFLVRNCESTKQDYSLSLKGAKGFMHMRIQRNETGQYIL 1375
Query: 294 G--GRTFECLDAVINRYRKEQI----VEGHTLGQPLIAE 326
G R FE + +I + ++ E L +P+IA+
Sbjct: 1376 GQFSRPFETVPEMIRHFCLNRLPVRGAEHMCLIEPVIAQ 1414
>UniRef50_Q9BI25 Cluster: SHK1 protein; n=2; Dictyostelium
discoideum|Rep: SHK1 protein - Dictyostelium discoideum
(Slime mold)
Length = 527
Score = 46.4 bits (105), Expect = 0.004
Identities = 25/76 (32%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 63 ETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRT-GINHFRITAVCG 121
E W+HG + SE RL +G++LVR S + G+Y +S + + GI+H RI G
Sbjct: 421 ECAWFHGDISTSESENRL-RQKPEGTFLVRFSTSEYGAYTISKVSKNGGISHQRIHRPQG 479
Query: 122 DYYIGGRQFDSLTELV 137
+ + ++ S+ EL+
Sbjct: 480 KFQVNNSKYLSVKELI 495
>UniRef50_Q965N4 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 427
Score = 46.4 bits (105), Expect = 0.004
Identities = 30/90 (33%), Positives = 51/90 (56%), Gaps = 9/90 (10%)
Query: 67 YHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYIG 126
+HG +DR +E+ L A +GSYLVRES+R + L + + ++++ G +Y+G
Sbjct: 51 FHGLIDRNEAEKMLLEAG-EGSYLVRESNRSRDACTLCMIFDAKVMNYKL-YYDGQFYVG 108
Query: 127 GRQFDSLTELV--GFYS-----HCSDLLKR 149
++FD++ LV G S H +D +KR
Sbjct: 109 EKRFDTMDLLVADGLISMFVDLHAADYIKR 138
Score = 40.3 bits (90), Expect = 0.24
Identities = 20/70 (28%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
Query: 236 FHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGG 295
FH ++EA ML++AG GS+LVR S+ S +L + ++ +++ G ++ +G
Sbjct: 51 FHGLIDRNEAEKMLLEAGEGSYLVRESNRSRDACTLCMIFDAKVMNYKLYYDG-QFYVGE 109
Query: 296 RTFECLDAVI 305
+ F+ +D ++
Sbjct: 110 KRFDTMDLLV 119
>UniRef50_A7RR81 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 473
Score = 46.4 bits (105), Expect = 0.004
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
+WYHG + R +E L +G +LVRES +PG YVLS + H + G
Sbjct: 378 DWYHGPISRGEAELLL---EDEGDFLVRESKSQPGQYVLSGIKDKQARHLLLVDPQGQVR 434
Query: 125 IGGRQFDSLTELVGFY 140
+ F+++ +L+ F+
Sbjct: 435 TRDKVFENVDQLISFH 450
>UniRef50_UPI0000D9EE2E Cluster: PREDICTED: similar to src homology
2 domain-containing transforming protein D; n=1; Macaca
mulatta|Rep: PREDICTED: similar to src homology 2
domain-containing transforming protein D - Macaca
mulatta
Length = 221
Score = 46.0 bits (104), Expect = 0.005
Identities = 32/95 (33%), Positives = 44/95 (46%), Gaps = 4/95 (4%)
Query: 50 STNGERQAVLAPPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRT 109
STN + P W+HG L+R +E L + K+GSYLVR S+ P LS
Sbjct: 105 STNTPGDTLCCCPIYGWFHGPLNRADAESLL-SLCKEGSYLVRLSETSPQDCSLSLRSSQ 163
Query: 110 GINHFRITAVCGDYYIGGRQ---FDSLTELVGFYS 141
G H + + + G+ F S+ ELV YS
Sbjct: 164 GFLHLKFARTRENQVVLGQHSGPFPSVPELVLHYS 198
Score = 37.1 bits (82), Expect = 2.2
Identities = 16/40 (40%), Positives = 24/40 (60%)
Query: 232 VFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSL 271
++ WFH +++A +L GS+LVR S+ SP D SL
Sbjct: 118 IYGWFHGPLNRADAESLLSLCKEGSYLVRLSETSPQDCSL 157
>UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 743
Score = 46.0 bits (104), Expect = 0.005
Identities = 26/80 (32%), Positives = 40/80 (50%), Gaps = 5/80 (6%)
Query: 66 WYHGRLDRYTSEERLWAAS---KQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGD 122
WYHG++ R + + ++G +LVRES R PGSYVL+ + + F+I
Sbjct: 10 WYHGKITRENAAHLVSQGPITRREGLFLVRESTRTPGSYVLTLWAKGNVQQFQIMGHGEG 69
Query: 123 YYI--GGRQFDSLTELVGFY 140
++ G F L EL+ Y
Sbjct: 70 WFSVDNGPLFQGLDELIHHY 89
Score = 43.6 bits (98), Expect = 0.025
Identities = 28/82 (34%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 235 WFHPNCTKSEAVDMLVKAGP-----GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV 289
W+H T+ A LV GP G FLVR S +PG Y L +Q+F+I G
Sbjct: 10 WYHGKITRENAAH-LVSQGPITRREGLFLVRESTRTPGSYVLTLWAKGNVQQFQIMGHGE 68
Query: 290 RYLM--GGRTFECLDAVINRYR 309
+ G F+ LD +I+ Y+
Sbjct: 69 GWFSVDNGPLFQGLDELIHHYQ 90
Score = 42.7 bits (96), Expect = 0.044
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Query: 65 EWYHGRLDRYTSEERLWAAS-KQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDY 123
++ H +DR + E L GS+L+R + RKPGSY L+ + + H+ + +
Sbjct: 291 DFLHKAIDRNNAVETLKQKGLSDGSFLIRPNSRKPGSYALTLVYKQTPYHYEVVCESDCW 350
Query: 124 YI--GGRQFDSLTELVGFYSHCSD 145
Y G FD+L +V Y+ +D
Sbjct: 351 YFIDDGPLFDTLPAVVDHYTIFAD 374
Score = 37.1 bits (82), Expect = 2.2
Identities = 22/78 (28%), Positives = 37/78 (47%), Gaps = 4/78 (5%)
Query: 235 WFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVR 290
+ H ++ AV+ L + G GSFL+RP+ PG Y+L + + E
Sbjct: 292 FLHKAIDRNNAVETLKQKGLSDGSFLIRPNSRKPGSYALTLVYKQTPYHYEVVCESDCWY 351
Query: 291 YLMGGRTFECLDAVINRY 308
++ G F+ L AV++ Y
Sbjct: 352 FIDDGPLFDTLPAVVDHY 369
>UniRef50_Q13239 Cluster: SRC-like-adapter; n=26; Euteleostomi|Rep:
SRC-like-adapter - Homo sapiens (Human)
Length = 276
Score = 46.0 bits (104), Expect = 0.005
Identities = 32/83 (38%), Positives = 44/83 (53%), Gaps = 4/83 (4%)
Query: 66 WYHGRLDRYTSEERLWAA-SKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGD-Y 123
W L R +EE L +K GS+++RES+ K G Y LS R + H+RI + + Y
Sbjct: 84 WLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHRQ-VKHYRIFRLPNNWY 142
Query: 124 YIGGR-QFDSLTELVGFYSHCSD 145
YI R F L +LV YS +D
Sbjct: 143 YISPRLTFQCLEDLVNHYSEVAD 165
Score = 44.4 bits (100), Expect = 0.014
Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 16/145 (11%)
Query: 169 VAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
+A+L PD F++G+ V +D G GW + TG + I P I
Sbjct: 27 LAVLSDYPSPDISPPIFRRGEKLRVISDEG-GWWKAISLSTGRESYI---------PGIC 76
Query: 229 PNTVF-SWFHPNCTKSEAVDMLVKAGP--GSFLVRPSDNSPGDYSLFFHINNQIQRFRIE 285
V+ W + +A ++L GSF++R S+ G YSL + Q++ +RI
Sbjct: 77 VARVYHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVR-HRQVKHYRIF 135
Query: 286 K--KGVRYLMGGRTFECLDAVINRY 308
+ Y+ TF+CL+ ++N Y
Sbjct: 136 RLPNNWYYISPRLTFQCLEDLVNHY 160
>UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein
tyrosine kinase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to protein tyrosine kinase - Nasonia
vitripennis
Length = 739
Score = 45.6 bits (103), Expect = 0.006
Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 5/82 (6%)
Query: 235 WFHPNCTKSEAVDMLVKAGP--GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYL 292
WFH N ++ +A +L++ G G+FLVR S +S GDY L + ++ ++I K G
Sbjct: 9 WFHGNLSREDAESLLLEDGRDNGTFLVRESSSSLGDYVLSVLHDGEVAHYQIRKHGEDAF 68
Query: 293 MG---GRTFECLDAVINRYRKE 311
T L+ +I Y+KE
Sbjct: 69 FSIDDETTIHGLETLIEYYQKE 90
Score = 41.5 bits (93), Expect = 0.10
Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 66 WYHGRLDRYTSEERLWAASKQ-GSYLVRESDRKPGSYVLSYLGRTGINHFRI 116
W+HG L R +E L + G++LVRES G YVLS L + H++I
Sbjct: 9 WFHGNLSREDAESLLLEDGRDNGTFLVRESSSSLGDYVLSVLHDGEVAHYQI 60
Score = 40.3 bits (90), Expect = 0.24
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 235 WFHPNCTKSEAVDMLVKAGP--GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK-KGVRY 291
W+H + EA+++L K G GSFLVR S+ G L N F+I+K + +
Sbjct: 283 WYHGTLDRMEAINLLHKNGDLDGSFLVRLSERHDGIRVLTVMYNKTPYHFQIQKRRNFLF 342
Query: 292 LMGGRTFECLDAVINRYR 309
+ G L+ VI YR
Sbjct: 343 IDNGPYLPSLEHVIEHYR 360
Score = 37.9 bits (84), Expect = 1.3
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 2/79 (2%)
Query: 64 TEWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGD 122
++WYHG LDR + L GS+LVR S+R G VL+ + HF+I
Sbjct: 281 SDWYHGTLDRMEAINLLHKNGDLDGSFLVRLSERHDGIRVLTVMYNKTPYHFQIQKRRNF 340
Query: 123 YYI-GGRQFDSLTELVGFY 140
+I G SL ++ Y
Sbjct: 341 LFIDNGPYLPSLEHVIEHY 359
>UniRef50_Q95XA9 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 346
Score = 45.6 bits (103), Expect = 0.006
Identities = 56/263 (21%), Positives = 102/263 (38%), Gaps = 13/263 (4%)
Query: 62 PETEWYHGRLDRYTSEERLWAA-----SKQGSYLVRESDRKPGSYVLSYLGR-TGINHFR 115
P WYHG L+ + + L + K G + G+ ++L R TG F
Sbjct: 37 PNDVWYHGELNEHDANHLLQVSFAKNYKKNGKKWQKTGKTFQGTSPGAFLVRQTGQTRFY 96
Query: 116 ITAVCGDYYIGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYT 175
++ + D Y LT F+ R+ + + + + + +
Sbjct: 97 LSILDQDGYPKHLPIRQLTPPHYFFEGKRFETLRDIVDAYQLAVIPEIQETKYLCVRRFE 156
Query: 176 KMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSW 235
+ + DE+ + GDI V GW+ +G G+I R +E L + + +
Sbjct: 157 QR-EIDEMNSEIGDILSVCETDETGWMLGRNETSGSVGIILRSHLEPLITEVADLSDLPY 215
Query: 236 FHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHIN-NQIQRFRIEKKGVR-YLM 293
F+ + + DM+ + G+FL+R S Y+L + +++F I R + +
Sbjct: 216 FY----DTVSTDMVQYSPIGTFLLRRSSKGTDTYALLVKTQFDLVEKFLIVGCPSRGFSL 271
Query: 294 GGRTFECLDAVINRYRKEQIVEG 316
GR F + V+ RY I G
Sbjct: 272 AGRPFPTIGHVLTRYCDRAISGG 294
>UniRef50_Q6CFF4 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 2545
Score = 45.6 bits (103), Expect = 0.006
Identities = 22/50 (44%), Positives = 28/50 (56%)
Query: 782 TRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLAN 831
T V FIFLR CPA+V P + LV ++ L +AK LQN+AN
Sbjct: 1304 TSAVGAFIFLRFFCPAIVSPESEGLVTAKLTGETRKECLQLAKLLQNMAN 1353
>UniRef50_Q2I6J0 Cluster: Phosphatidylinositol-3,4,5-trisphosphate
5-phosphatase 2B; n=6; Euteleostomi|Rep:
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase
2B - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 1226
Score = 45.6 bits (103), Expect = 0.006
Identities = 21/51 (41%), Positives = 31/51 (60%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI 116
WYH + R +EE L A GS+LVR+S+ PG+Y L L + ++ +RI
Sbjct: 6 WYHRDISRVRAEELLAHAGIDGSFLVRDSESVPGAYALCLLFQRHVHTYRI 56
Score = 41.5 bits (93), Expect = 0.10
Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 1/51 (1%)
Query: 235 WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRI 284
W+H + ++ A ++L AG GSFLVR S++ PG Y+L + +RI
Sbjct: 6 WYHRDISRVRAEELLAHAGIDGSFLVRDSESVPGAYALCLLFQRHVHTYRI 56
>UniRef50_Q56A36 Cluster: Hematopoietic SH2 domain-containing
protein homolog; n=3; Danio rerio|Rep: Hematopoietic SH2
domain-containing protein homolog - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 365
Score = 45.6 bits (103), Expect = 0.006
Identities = 31/91 (34%), Positives = 44/91 (48%), Gaps = 5/91 (5%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAV-CGDY 123
EW+HG + R +EE L G +L+R S+ + G Y LSY HF I + +
Sbjct: 33 EWFHGIISRKAAEEML-MCKPAGYFLIRVSESRVG-YTLSYRAEDRCRHFMINVLPDNQF 90
Query: 124 YIGGRQ--FDSLTELVGFYSHCSDLLKRERL 152
I G + + SL +LV F+ C L E L
Sbjct: 91 MIVGEKTVYCSLHDLVAFHRRCPILPYNELL 121
>UniRef50_UPI000065F097 Cluster: Hematopoietic SH2 domain-containing
protein (Hematopoietic SH2 protein) (Adaptor in
lymphocytes of unknown function X).; n=1; Takifugu
rubripes|Rep: Hematopoietic SH2 domain-containing
protein (Hematopoietic SH2 protein) (Adaptor in
lymphocytes of unknown function X). - Takifugu rubripes
Length = 266
Score = 45.2 bits (102), Expect = 0.008
Identities = 29/81 (35%), Positives = 43/81 (53%), Gaps = 5/81 (6%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAV-CGDY 123
+W+HG + R +EE L A +G +L+R S+ + G Y LSY HF I + G +
Sbjct: 22 DWFHGIITRKAAEE-LLAPRPRGCFLIRVSESRAG-YTLSYRAEDRCKHFMIDVMEDGCF 79
Query: 124 YIGG--RQFDSLTELVGFYSH 142
I G R+ L +LV F+ H
Sbjct: 80 IIVGEKRRHQFLQDLVDFHRH 100
Score = 35.5 bits (78), Expect = 6.7
Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Query: 223 LDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRF 282
L S + WFH T+ A ++L G FL+R S++ G Y+L + ++ + F
Sbjct: 11 LRSSFSTGAIPDWFHGIITRKAAEELLAPRPRGCFLIRVSESRAG-YTLSYRAEDRCKHF 69
Query: 283 RIE 285
I+
Sbjct: 70 MID 72
>UniRef50_Q8T6F8 Cluster: SRC-1; n=3; Caenorhabditis|Rep: SRC-1 -
Caenorhabditis elegans
Length = 533
Score = 45.2 bits (102), Expect = 0.008
Identities = 28/108 (25%), Positives = 54/108 (50%), Gaps = 3/108 (2%)
Query: 164 DKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDL 223
+++ +VA+ PY D D L+FQKGD ++ + W +V RTG+ G + R V
Sbjct: 72 ERETLVALYPYDSRADGD-LSFQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFVAK- 129
Query: 224 DPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSL 271
+I+ ++ P ++E + + G+FL+R + +++L
Sbjct: 130 QQTIESEEWYAGKIPR-NRAERLVLSSHLPKGTFLIREREADTREFAL 176
Score = 37.9 bits (84), Expect = 1.3
Identities = 28/91 (30%), Positives = 48/91 (52%), Gaps = 10/91 (10%)
Query: 65 EWYHGRLDRYTSEERLWAAS-KQGSYLVRESDRKPGSYVLSYLG----RTG--INHFRIT 117
EWY G++ R +E + ++ +G++L+RE + + L+ R G + H++I
Sbjct: 137 EWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGGTVKHYKIK 196
Query: 118 AVCGD--YYIGGRQ-FDSLTELVGFYSHCSD 145
+ D Y+I R+ F SL ELV +YS D
Sbjct: 197 RLDHDQGYFITTRRTFRSLQELVRYYSDVPD 227
>UniRef50_P42687 Cluster: Tyrosine-protein kinase SPK-1; n=1;
Girardia tigrina|Rep: Tyrosine-protein kinase SPK-1 -
Dugesia tigrina (Planarian)
Length = 497
Score = 45.2 bits (102), Expect = 0.008
Identities = 39/160 (24%), Positives = 72/160 (45%), Gaps = 14/160 (8%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
V A Y DTD ++F++ +I +V + WL V + ++G++ V D S
Sbjct: 38 VKAKYKYAASGDTD-ISFEEKEIMYVLEQFDEFWLKVVKQKDNKEGLVPSNYVSKQDGS- 95
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQ------IQR 281
P +V +W ++E M + G++++RPS Y+L ++ ++
Sbjct: 96 -PQSVEAWREIQRWEAEKSLMKIGLQKGTYIIRPS-RKENSYALSVRDFDEKKKICIVKH 153
Query: 282 FRI----EKKGVRYLMGGRTFECLDAVINRYRKEQIVEGH 317
F+I ++KG+ Y + R F + +I Y K I H
Sbjct: 154 FQIKTLQDEKGISYSVNIRNFPNILTLIQFYEKNGIGNTH 193
>UniRef50_P08630 Cluster: Tyrosine-protein kinase Btk29A; n=10;
Endopterygota|Rep: Tyrosine-protein kinase Btk29A -
Drosophila melanogaster (Fruit fly)
Length = 786
Score = 45.2 bits (102), Expect = 0.008
Identities = 30/102 (29%), Positives = 54/102 (52%), Gaps = 8/102 (7%)
Query: 49 PSTNGERQAVLAPPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSY--- 105
PS + +A+L EWY G + R +E L K+G ++VR+S K G Y LS
Sbjct: 393 PSNYVKPKALLGLERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKSSTK-GLYTLSLHTK 451
Query: 106 LGRTGINHFRI--TAVCGDYYIGGRQ-FDSLTELVGFYSHCS 144
+ ++ + H+ I A C +YY+ + +++ +L+ ++ H S
Sbjct: 452 VPQSHVKHYHIKQNARC-EYYLSEKHCCETIPDLINYHRHNS 492
>UniRef50_UPI0000DB7727 Cluster: PREDICTED: similar to Tensin-1; n=1;
Apis mellifera|Rep: PREDICTED: similar to Tensin-1 - Apis
mellifera
Length = 1847
Score = 44.8 bits (101), Expect = 0.011
Identities = 19/52 (36%), Positives = 32/52 (61%)
Query: 220 VEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSL 271
V D++ +T W+ PN ++ +A+ ML A PG+F+VR S++ PG + L
Sbjct: 1294 VADVNVKFVRDTSRIWYKPNISREQAISMLKDAAPGTFVVRDSNSFPGAFGL 1345
>UniRef50_Q3ZB94 Cluster: Zgc:113360; n=3; Clupeocephala|Rep:
Zgc:113360 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 271
Score = 44.8 bits (101), Expect = 0.011
Identities = 30/83 (36%), Positives = 43/83 (51%), Gaps = 4/83 (4%)
Query: 66 WYHGRLDRYTSEERL-WAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGD-Y 123
W + R +EE L + GS+L+RES R+ G Y LS R+ + H++I + Y
Sbjct: 84 WLFEGVSRQKAEELLSLPGNSAGSFLIRESPRERGLYSLSVRHRS-VKHYKIFRLTNSWY 142
Query: 124 YIGGR-QFDSLTELVGFYSHCSD 145
YI R F L ++V YS SD
Sbjct: 143 YISPRLTFQCLEDMVNHYSDSSD 165
Score = 36.3 bits (80), Expect = 3.8
Identities = 22/78 (28%), Positives = 39/78 (50%), Gaps = 5/78 (6%)
Query: 235 WFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK--KGVR 290
W ++ +A ++L G GSFL+R S G YSL + ++ ++I +
Sbjct: 84 WLFEGVSRQKAEELLSLPGNSAGSFLIRESPRERGLYSLSVR-HRSVKHYKIFRLTNSWY 142
Query: 291 YLMGGRTFECLDAVINRY 308
Y+ TF+CL+ ++N Y
Sbjct: 143 YISPRLTFQCLEDMVNHY 160
>UniRef50_Q1LX18 Cluster: Novel protein similar to vertebrate src
homology 2 domain containing transforming protein C3;
n=1; Danio rerio|Rep: Novel protein similar to
vertebrate src homology 2 domain containing transforming
protein C3 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 501
Score = 44.8 bits (101), Expect = 0.011
Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 8/91 (8%)
Query: 55 RQAVLAPPETE-----WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRT 109
R+A +AP E + WYHGR+ R +E L + G +LVR+S PG YVL+ +
Sbjct: 390 RRAPVAPTEDQLRREMWYHGRMSRRDAENLL---GRDGDFLVRDSATNPGQYVLTGMQCG 446
Query: 110 GINHFRITAVCGDYYIGGRQFDSLTELVGFY 140
H + G F+S++ L+ ++
Sbjct: 447 LPKHLLLVDPEGVVRTKDMLFESISHLINYH 477
>UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep:
Zgc:153964 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 511
Score = 44.8 bits (101), Expect = 0.011
Identities = 40/152 (26%), Positives = 64/152 (42%), Gaps = 6/152 (3%)
Query: 176 KMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSW 235
K + EL+F+ GD F + + GD W TA++ G + V + D W
Sbjct: 78 KARNDQELSFKAGDKFEITDRSGDWW---TANKKDIFGRVTTGFVPYNYLARDSVESQPW 134
Query: 236 FHPNCTKSEAVDMLV--KAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLM 293
F + AV L+ + GSFLVR S++ Y L + F+I + G ++ +
Sbjct: 135 FFGKMNRVGAVSHLMSDENNYGSFLVRVSESDDMGYVLSVRTKENAKHFKIFQTGDQFYV 194
Query: 294 GGR-TFECLDAVINRYRKEQIVEGHTLGQPLI 324
F + VI Y+ + G L +P I
Sbjct: 195 DALFKFSSIVEVIEHYQSHPLSIGDLLSEPCI 226
Score = 41.9 bits (94), Expect = 0.077
Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 66 WYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
W+ G+++R + L + + GS+LVR S+ YVLS + HF+I +Y
Sbjct: 134 WFFGKMNRVGAVSHLMSDENNYGSFLVRVSESDDMGYVLSVRTKENAKHFKIFQTGDQFY 193
Query: 125 IGGR-QFDSLTELVGFY-SH 142
+ +F S+ E++ Y SH
Sbjct: 194 VDALFKFSSIVEVIEHYQSH 213
>UniRef50_Q6MGD1 Cluster: Synaptic Ras GTPase activating protein;
n=4; Eutheria|Rep: Synaptic Ras GTPase activating
protein - Rattus norvegicus (Rat)
Length = 392
Score = 44.8 bits (101), Expect = 0.011
Identities = 51/181 (28%), Positives = 77/181 (42%), Gaps = 22/181 (12%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
VH S+ +EFCF++ + T F A +A E WIE L+ P + + R
Sbjct: 194 VHSSILGQEFCFEVTTSS----GTKCF-ACRSAAERDKWIENLQRAVKPNKDNSR----R 244
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRP---SPDPHWXXXXXXXX 537
V VL L + + A LP + R + + L ART +P S D +
Sbjct: 245 VDNVLKLWI--IEARELPPK--KRYYCELCLDDMLYARTTSKPRSASGDTVFWGEHFEFN 300
Query: 538 MPPDVTSLTITVHNTG----KRGKESEVAELTIELANLANGEEIEEWYPLVGMTPIGEWG 593
P V +L + ++ K+ K V +T+ +A LA E+WYP+ P G G
Sbjct: 301 NLPAVRALRLHLYRDSDKKRKKDKAGYVGLVTVPVATLAGRHFTEQWYPVT--LPTGSGG 358
Query: 594 S 594
S
Sbjct: 359 S 359
>UniRef50_Q7K137 Cluster: LD10453p; n=4; Diptera|Rep: LD10453p -
Drosophila melanogaster (Fruit fly)
Length = 723
Score = 44.8 bits (101), Expect = 0.011
Identities = 25/63 (39%), Positives = 36/63 (57%), Gaps = 5/63 (7%)
Query: 231 TVFSWFHPNCTKSEAVDMLVK---AGPGSFLVRPSDNSPGDYSLFFHINNQIQRFR--IE 285
+VF WFH T+SEA M++ AG G FLVR S+ G++ L F+ + + R I
Sbjct: 438 SVFPWFHGTLTRSEAARMVLHSDAAGHGYFLVRQSETRRGEFVLTFNFQGRAKHLRLTIS 497
Query: 286 KKG 288
+KG
Sbjct: 498 EKG 500
Score = 37.5 bits (83), Expect = 1.7
Identities = 22/80 (27%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 66 WYHGRLDRYTSEERLWA--ASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRIT-AVCGD 122
W+HG L R + + A+ G +LVR+S+ + G +VL++ + H R+T + G
Sbjct: 442 WFHGTLTRSEAARMVLHSDAAGHGYFLVRQSETRRGEFVLTFNFQGRAKHLRLTISEKGQ 501
Query: 123 YYIGGRQFDSLTELVGFYSH 142
+ F S+ E++ + H
Sbjct: 502 CRVQHLWFPSIQEMLEHFRH 521
>UniRef50_O88890 Cluster: SH2 domain-containing protein 1A; n=8;
Eutheria|Rep: SH2 domain-containing protein 1A - Mus
musculus (Mouse)
Length = 126
Score = 44.8 bits (101), Expect = 0.011
Identities = 21/51 (41%), Positives = 31/51 (60%)
Query: 67 YHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRIT 117
YHG++ R T E+ L A GSYL+R+S+ PG Y L L + I +R++
Sbjct: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYQGYIYTYRVS 57
>UniRef50_UPI000155BC71 Cluster: PREDICTED: similar to inositol
polyphosphate 5- phosphatase; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to inositol
polyphosphate 5- phosphatase - Ornithorhynchus anatinus
Length = 1019
Score = 44.4 bits (100), Expect = 0.014
Identities = 33/90 (36%), Positives = 49/90 (54%), Gaps = 8/90 (8%)
Query: 232 VFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRI-----E 285
V W H N T+S+A ++L K G GSFLVR S++ Y+L +N + +RI E
Sbjct: 2 VHCWNHGNITRSKAEELLSKTGKDGSFLVRASESISRAYALCVLYHNCVYTYRILPNDDE 61
Query: 286 KKGVRYLMG--GRTFECLDAVINRYRKEQI 313
K V+ G R F L+ +I+ Y+KE +
Sbjct: 62 KFTVQASEGVPMRFFTSLEQLIDFYKKENM 91
Score = 39.5 bits (88), Expect = 0.41
Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 7/82 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRIT-------A 118
W HG + R +EE L K GS+LVR S+ +Y L L + +RI
Sbjct: 5 WNHGNITRSKAEELLSKTGKDGSFLVRASESISRAYALCVLYHNCVYTYRILPNDDEKFT 64
Query: 119 VCGDYYIGGRQFDSLTELVGFY 140
V + R F SL +L+ FY
Sbjct: 65 VQASEGVPMRFFTSLEQLIDFY 86
>UniRef50_UPI0000D8C686 Cluster: Breast cancer anti-estrogen
resistance protein 3 (SH2 domain- containing protein 3B)
(Novel SH2-containing protein 2).; n=1; Danio rerio|Rep:
Breast cancer anti-estrogen resistance protein 3 (SH2
domain- containing protein 3B) (Novel SH2-containing
protein 2). - Danio rerio
Length = 628
Score = 44.4 bits (100), Expect = 0.014
Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 15/120 (12%)
Query: 217 RELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHIN 276
REL E+L S + +W+H + A +++ + G FL+R S +SPG+Y L
Sbjct: 28 RELEEELKLSSEEPRSHAWYHGAIPRQVAENLVQR--DGDFLIRDSLSSPGNYVLTCQWK 85
Query: 277 NQIQRFRIEKK---------GVRYLMGGRTFECLDAVINRY--RKEQIVE--GHTLGQPL 323
N Q F+I K+ V+YL F+ + A++ Y +E + E G + QP+
Sbjct: 86 NSPQHFKINKRVVAMNEAYSRVQYLFEKEGFDSIPALVRYYVGNREPVSEVIGAIIFQPI 145
Score = 43.2 bits (97), Expect = 0.033
Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 12/89 (13%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHF----RI 116
P WYHG + R +E + + G +L+R+S PG+YVL+ + HF R+
Sbjct: 41 PRSHAWYHGAIPRQVAENLV---QRDGDFLIRDSLSSPGNYVLTCQWKNSPQHFKINKRV 97
Query: 117 TAVCGDY----YIGGRQ-FDSLTELVGFY 140
A+ Y Y+ ++ FDS+ LV +Y
Sbjct: 98 VAMNEAYSRVQYLFEKEGFDSIPALVRYY 126
>UniRef50_O60880 Cluster: SH2 domain-containing protein 1A; n=18;
Euteleostomi|Rep: SH2 domain-containing protein 1A -
Homo sapiens (Human)
Length = 128
Score = 44.4 bits (100), Expect = 0.014
Identities = 21/51 (41%), Positives = 30/51 (58%)
Query: 67 YHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRIT 117
YHG++ R T E+ L A GSYL+R+S+ PG Y L L I +R++
Sbjct: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVS 57
>UniRef50_Q14847 Cluster: LIM and SH3 domain protein 1; n=44;
Euteleostomi|Rep: LIM and SH3 domain protein 1 - Homo
sapiens (Human)
Length = 261
Score = 44.4 bits (100), Expect = 0.014
Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
Query: 166 KRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVE 221
KR A+ Y+ D DE++FQ GD + DGW++ T RTG+ GM+ VE
Sbjct: 205 KRYRAVYDYSAA-DEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVE 259
>UniRef50_UPI0000F2E785 Cluster: PREDICTED: hypothetical protein;
n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
protein - Monodelphis domestica
Length = 197
Score = 44.0 bits (99), Expect = 0.019
Identities = 21/51 (41%), Positives = 30/51 (58%)
Query: 67 YHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRIT 117
YHG + R T E+ L A GSYL+R+S+ PG Y L L + I +R++
Sbjct: 7 YHGNISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYQGYIYTYRVS 57
>UniRef50_UPI0000F201D0 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 475
Score = 44.0 bits (99), Expect = 0.019
Identities = 20/54 (37%), Positives = 31/54 (57%), Gaps = 3/54 (5%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAV 119
WYHG+L R +E+ L + G +LVR+S G YVL+ + + HF+I +
Sbjct: 27 WYHGQLQREATEQLL---GRDGEFLVRDSSTSAGDYVLTCMWKNQPMHFKIIRI 77
Score = 39.1 bits (87), Expect = 0.54
Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Query: 217 RELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHIN 276
+EL E+L S + +W+H + EA + L+ G FLVR S S GDY L
Sbjct: 9 KELEEELKLSTEDLRSQAWYHGQLQR-EATEQLL-GRDGEFLVRDSSTSAGDYVLTCMWK 66
Query: 277 NQIQRFRIEKKGVRYLMG 294
NQ F+I + +R G
Sbjct: 67 NQPMHFKIIRITLRPKQG 84
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.321 0.136 0.422
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,051,366,976
Number of Sequences: 1657284
Number of extensions: 44365626
Number of successful extensions: 93755
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 253
Number of HSP's successfully gapped in prelim test: 249
Number of HSP's that attempted gapping in prelim test: 92689
Number of HSP's gapped (non-prelim): 989
length of query: 932
length of database: 575,637,011
effective HSP length: 108
effective length of query: 824
effective length of database: 396,650,339
effective search space: 326839879336
effective search space used: 326839879336
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 77 (35.1 bits)
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