Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001560-TA|BGIBMGA001560-PA|IPR000980|SH2 motif,
IPR001452|Src homology-3, IPR001849|Pleckstrin-like, IPR001936|Ras
GTPase-activating protein, IPR000008|C2 calcium-dependent membrane
targeting, IPR008936|Rho GTPase activation protein, IPR008973|C2
calcium/lipid-binding region, CaLB
(932 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M23379-1|AAA52517.1| 1047|Homo sapiens GTPase-activating protein... 725 0.0
BC033015-1|AAH33015.1| 1047|Homo sapiens RAS p21 protein activat... 725 0.0
M23612-1|AAA35865.1| 870|Homo sapiens GTPase-activating protein... 718 0.0
AB209106-1|BAD92343.1| 871|Homo sapiens RAS p21 protein activat... 525 e-148
BC020761-1|AAH20761.1| 317|Homo sapiens Unknown (protein for IM... 314 7e-85
BC054891-1|AAH54891.1| 313|Homo sapiens RASA1 protein protein. 313 2e-84
BC110611-1|AAI10612.1| 1262|Homo sapiens RASAL2 protein protein. 173 2e-42
AL499617-1|CAH72349.1| 1269|Homo sapiens RAS protein activator l... 168 7e-41
AL365357-2|CAI22693.1| 1139|Homo sapiens RAS protein activator l... 168 7e-41
AL365357-1|CAI22692.1| 1269|Homo sapiens RAS protein activator l... 168 7e-41
AL160281-1|CAH71462.1| 1269|Homo sapiens RAS protein activator l... 168 7e-41
AL035702-3|CAI21912.1| 1139|Homo sapiens RAS protein activator l... 168 7e-41
AL035702-1|CAI21910.1| 1269|Homo sapiens RAS protein activator l... 168 7e-41
AF047711-1|AAD04814.1| 1139|Homo sapiens nGAP protein. 168 7e-41
AK122587-1|BAC56928.1| 749|Homo sapiens FLJ00412 protein protein. 165 8e-40
AY032952-1|AAK50336.1| 1065|Homo sapiens nGAP-like protein protein. 161 1e-38
AL365274-4|CAH72158.1| 1065|Homo sapiens DAB2 interacting protei... 161 1e-38
AL365274-1|CAH72155.2| 1132|Homo sapiens DAB2 interacting protei... 161 1e-38
AL357936-1|CAI15112.2| 1132|Homo sapiens DAB2 interacting protei... 161 1e-38
AB051530-1|BAB21834.2| 1036|Homo sapiens KIAA1743 protein protein. 161 1e-38
AK024488-1|BAB15778.1| 674|Homo sapiens FLJ00087 protein protein. 157 2e-37
AF367051-1|AAM00371.1| 967|Homo sapiens DOC-2/DAB2 interactive ... 147 2e-34
AB208935-1|BAD92172.1| 818|Homo sapiens RasGAP-activating-like ... 141 1e-32
BC093724-1|AAH93724.1| 804|Homo sapiens RAS protein activator l... 140 2e-32
BC014420-1|AAH14420.1| 776|Homo sapiens RASAL1 protein protein. 140 2e-32
AF086713-1|AAD09006.1| 804|Homo sapiens rasGAP-activating-like ... 140 2e-32
X89399-1|CAA61580.1| 834|Homo sapiens Ins P4-binding protein pr... 138 1e-31
BX537329-1|CAM28365.1| 834|Homo sapiens RAS p21 protein activat... 138 1e-31
BC047242-1|AAH47242.1| 834|Homo sapiens RAS p21 protein activat... 138 1e-31
BC038456-1|AAH38456.1| 834|Homo sapiens RAS p21 protein activat... 138 1e-31
AL161774-1|CAI12864.2| 834|Homo sapiens RAS p21 protein activat... 138 1e-31
BX088650-15|CAM26306.1| 1284|Homo sapiens synaptic Ras GTPase ac... 136 3e-31
BX088650-14|CAM26305.1| 1343|Homo sapiens synaptic Ras GTPase ac... 136 3e-31
BX088650-13|CAM26304.1| 1299|Homo sapiens synaptic Ras GTPase ac... 136 3e-31
AL662799-15|CAM25572.1| 1284|Homo sapiens synaptic Ras GTPase ac... 136 3e-31
AL662799-14|CAI18276.2| 1343|Homo sapiens synaptic Ras GTPase ac... 136 3e-31
AB067525-1|BAB67831.2| 1376|Homo sapiens KIAA1938 protein protein. 136 3e-31
D82880-1|BAA11621.1| 853|Homo sapiens human ras GTPase-activati... 123 3e-27
D78155-1|BAA11230.1| 850|Homo sapiens rasGTPase activating prot... 123 3e-27
AF115573-1|AAD09821.1| 849|Homo sapiens GTPase-activating prote... 123 3e-27
AL713634-1|CAD28452.1| 902|Homo sapiens hypothetical protein pr... 118 1e-25
AC105052-1|AAP22345.1| 724|Homo sapiens unknown protein. 105 6e-22
AB011110-1|BAA25464.2| 816|Homo sapiens KIAA0538 protein protein. 105 6e-22
BC113663-1|AAI13664.1| 803|Homo sapiens RAS p21 protein activat... 105 7e-22
BC110873-1|AAI10874.1| 803|Homo sapiens RAS p21 protein activat... 105 7e-22
AY029206-1|AAK31582.1| 803|Homo sapiens calcium-promoted Ras in... 105 7e-22
U17690-2|AAB48379.1| 840|Homo sapiens neurofibromatosis 1 protein. 94 2e-18
M82814-1|AAA59924.1| 2818|Homo sapiens GAP-related protein protein. 94 2e-18
M61213-1|AAA59923.1| 482|Homo sapiens neurofibromatosis protein... 94 2e-18
M60915-2|AAA59922.1| 378|Homo sapiens neurofibromatosis protein... 94 2e-18
M38107-1|AAB59558.1| 2503|Homo sapiens neurofibromatosis protein... 94 2e-18
M38106-1|AAA74897.1| 2485|Homo sapiens neurofibromatosis type 1 ... 94 2e-18
AY796305-1|AAV50004.1| 2818|Homo sapiens neurofibromin 1 (neurof... 94 2e-18
AB209336-1|BAD92573.1| 968|Homo sapiens neurofibromin variant p... 94 2e-18
U17690-1|AAB48380.1| 861|Homo sapiens neurofibromatosis 1 protein. 83 3e-15
M89914-1|AAA59925.1| 2839|Homo sapiens neurofibromin protein. 83 3e-15
M60915-1|AAA59921.1| 399|Homo sapiens neurofibromatosis protein... 83 3e-15
CR450363-1|CAG29359.1| 217|Homo sapiens GRB2 protein. 69 6e-11
X62852-1|CAA44664.1| 160|Homo sapiens ash protein protein. 66 4e-10
M96995-1|AAA58448.1| 217|Homo sapiens epidermal growth factor r... 66 4e-10
CR541942-1|CAG46740.1| 217|Homo sapiens GRB2 protein. 66 4e-10
BC000631-1|AAH00631.1| 217|Homo sapiens growth factor receptor-... 66 4e-10
AF498925-1|AAM21073.1| 217|Homo sapiens growth factor receptor-... 66 4e-10
AF063618-1|AAC72075.1| 217|Homo sapiens growth factor receptor-... 66 4e-10
U52518-1|AAC50541.1| 217|Homo sapiens Grb2-related adaptor prot... 65 1e-09
CR541966-1|CAG46764.1| 217|Homo sapiens GRAP protein. 65 1e-09
CR541941-1|CAG46739.1| 217|Homo sapiens GRAP protein. 65 1e-09
BT019981-1|AAV38784.1| 217|Homo sapiens GRB2-related adaptor pr... 65 1e-09
BC063035-1|AAH63035.1| 217|Homo sapiens GRB2-related adaptor pr... 65 1e-09
BC035856-1|AAH35856.1| 217|Homo sapiens GRB2-related adaptor pr... 65 1e-09
L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein. 63 4e-09
S71669-1|AAB30995.1| 465|Homo sapiens lsk protein. 63 5e-09
X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein. 62 7e-09
S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated ... 62 7e-09
BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associate... 62 7e-09
BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associate... 62 7e-09
AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein. 62 7e-09
X70766-1|CAA50045.1| 593|Homo sapiens protein-tyrosine phosphat... 61 2e-08
L07527-1|AAA17022.1| 593|Homo sapiens protein-tyrosine phosphat... 61 2e-08
L03535-1|AAA36611.1| 593|Homo sapiens phosphotyrosyl-protein ph... 61 2e-08
D13540-1|BAA02740.2| 593|Homo sapiens protein-tyrosine phosphat... 61 2e-08
BT007106-1|AAP35770.1| 460|Homo sapiens protein tyrosine phosph... 61 2e-08
BC008692-1|AAH08692.1| 460|Homo sapiens PTPN11 protein protein. 61 2e-08
BC012924-1|AAH12924.1| 280|Homo sapiens DAPP1 protein protein. 60 4e-08
AF186022-1|AAF14578.1| 280|Homo sapiens B lymphocyte adapter pr... 60 4e-08
AF178987-1|AAF44351.1| 280|Homo sapiens protein-tyrosine phosph... 60 4e-08
AF163254-1|AAD49697.1| 280|Homo sapiens adaptor protein DAPP1 p... 60 4e-08
Z82206-3|CAI42713.1| 330|Homo sapiens GRB2-related adaptor prot... 59 6e-08
Y18051-1|CAA77021.1| 330|Homo sapiens GADS protein protein. 59 6e-08
CR541849-1|CAG46647.1| 330|Homo sapiens GRAP2 protein. 59 6e-08
CR536524-1|CAG38761.1| 330|Homo sapiens GRAP2 protein. 59 6e-08
CR456498-1|CAG30384.1| 330|Homo sapiens GRAP2 protein. 59 6e-08
BC026002-1|AAH26002.1| 330|Homo sapiens GRAP2 protein protein. 59 6e-08
BC025692-1|AAH25692.1| 330|Homo sapiens GRB2-related adaptor pr... 59 6e-08
AY069959-1|AAL58573.1| 330|Homo sapiens Mona protein. 59 6e-08
AJ011736-1|CAA09757.1| 330|Homo sapiens growth factor receptor ... 59 6e-08
AF236120-1|AAF60320.1| 330|Homo sapiens adapter protein GRID pr... 59 6e-08
AF236119-1|AAF60319.1| 330|Homo sapiens adapter protein GRID pr... 59 6e-08
AF129476-1|AAD41782.1| 330|Homo sapiens hematopoietic cell-asso... 59 6e-08
AF121002-1|AAF31758.1| 330|Homo sapiens SH3-SH2-SH3 adaptor pro... 59 6e-08
AF102694-1|AAD04926.1| 330|Homo sapiens Grb2-related adaptor pr... 59 6e-08
AF090456-1|AAD13027.1| 330|Homo sapiens Grb-2-like protein prot... 59 6e-08
AF042380-1|AAC69273.1| 330|Homo sapiens Grf40 adaptor protein p... 59 6e-08
D78156-1|BAA11231.1| 410|Homo sapiens rasGTPase activating prot... 58 1e-07
J03358-1|AAA61190.1| 822|Homo sapiens FER protein. 58 2e-07
M34667-1|AAA36452.1| 1290|Homo sapiens protein ( Human phospholi... 57 3e-07
DQ297143-1|ABB84466.1| 1291|Homo sapiens phospholipase C, gamma ... 57 3e-07
AL022394-3|CAA18537.1| 1290|Homo sapiens phospholipase C, gamma ... 57 3e-07
AL022394-2|CAM28260.1| 1291|Homo sapiens phospholipase C, gamma ... 57 3e-07
AB210028-1|BAE06110.1| 1412|Homo sapiens PLCG1 variant protein p... 57 3e-07
X59656-1|CAA42199.1| 303|Homo sapiens CRKL protein. 57 3e-07
K03218-1|AAA60584.1| 536|Homo sapiens SRC protein. 57 3e-07
CR456423-1|CAG30309.1| 303|Homo sapiens CRKL protein. 57 3e-07
BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma (Schmidt-... 57 3e-07
BC043500-1|AAH43500.1| 303|Homo sapiens v-crk sarcoma virus CT1... 57 3e-07
BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein. 57 3e-07
AL133293-2|CAC10573.1| 542|Homo sapiens v-src sarcoma (Schmidt-... 57 3e-07
AL133293-1|CAC34523.1| 536|Homo sapiens v-src sarcoma (Schmidt-... 57 3e-07
X17576-1|CAA35599.1| 377|Homo sapiens protein ( Human melanoma ... 56 8e-07
BC006403-1|AAH06403.1| 377|Homo sapiens NCK adaptor protein 1 p... 56 8e-07
X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase p... 54 2e-06
X62055-1|CAA43982.1| 597|Homo sapiens protein-tyrosine phospha... 54 2e-06
X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine... 54 2e-06
X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein. 54 2e-06
X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyros... 54 2e-06
U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase ... 54 2e-06
U47924-18|AAB51323.1| 595|Homo sapiens protein tyrosine phospha... 54 2e-06
U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia... 54 2e-06
M77273-1|AAA36610.1| 595|Homo sapiens tyrosine phosphatase prot... 54 2e-06
M74903-1|AAA35963.1| 595|Homo sapiens hematopoietic cell phopha... 54 2e-06
L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia... 54 2e-06
DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase p... 54 2e-06
CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein. 54 2e-06
BT007390-1|AAP36054.1| 597|Homo sapiens protein tyrosine phosph... 54 2e-06
BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinem... 54 2e-06
BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinem... 54 2e-06
BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase p... 54 2e-06
BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase p... 54 2e-06
BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase p... 54 2e-06
BC007667-1|AAH07667.1| 597|Homo sapiens protein tyrosine phosph... 54 2e-06
BC002523-1|AAH02523.1| 597|Homo sapiens protein tyrosine phosph... 54 2e-06
AL035422-4|CAI42359.1| 483|Homo sapiens Bruton agammaglobulinem... 54 2e-06
AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinem... 54 2e-06
AK223629-1|BAD97349.1| 595|Homo sapiens protein tyrosine phosph... 54 2e-06
AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase v... 54 2e-06
AF178946-1|AAD53317.1| 624|Homo sapiens 70 kDa SHP-1L protein p... 54 2e-06
AB079851-2|BAC81775.1| 595|Homo sapiens protein tyrosine phosph... 54 2e-06
AB079851-1|BAC81774.1| 597|Homo sapiens protein tyrosine phosph... 54 2e-06
BC007195-1|AAH07195.1| 380|Homo sapiens NCK adaptor protein 2 p... 54 2e-06
BC000103-1|AAH00103.1| 380|Homo sapiens NCK adaptor protein 2 p... 54 2e-06
AF047487-1|AAC80284.1| 380|Homo sapiens Nck-2 protein. 54 2e-06
AF043119-1|AAC04831.1| 381|Homo sapiens SH2/SH3 adaptor protein... 54 2e-06
AC009505-1|AAY24332.1| 304|Homo sapiens unknown protein. 54 2e-06
U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase ... 54 3e-06
BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase prot... 54 3e-06
AM491363-1|CAM33013.1| 498|Homo sapiens bcr-abl1 e19a2 chimeric... 54 3e-06
AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase prot... 54 3e-06
AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase prot... 54 3e-06
U47924-17|AAB51322.1| 556|Homo sapiens protein tyrosine phospha... 53 4e-06
U22322-1|AAC50116.1| 505|Homo sapiens Rak protein. 53 4e-06
X73568-1|CAA51970.1| 630|Homo sapiens protein tyrosin kinase pr... 53 5e-06
X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRN... 53 5e-06
U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene tyrosine-p... 53 5e-06
U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene tyrosine-p... 53 5e-06
DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine le... 53 5e-06
BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine le... 53 5e-06
AM491362-1|CAM33012.1| 585|Homo sapiens bcr-abl1 e6a2 chimeric ... 53 5e-06
AM491361-1|CAM33011.1| 313|Homo sapiens bcr-abl1 e1a3 chimeric ... 53 5e-06
AM491360-1|CAM33010.1| 260|Homo sapiens bcr-abl1 e14a3 chimeric... 53 5e-06
AM491359-1|CAM33009.1| 235|Homo sapiens bcr-abl1 e13a3 chimeric... 53 5e-06
AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine l... 53 5e-06
AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine le... 53 5e-06
AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine le... 53 5e-06
AJ131467-1|CAA10377.1| 307|Homo sapiens BCR/ABL chimeric fusion... 53 5e-06
AJ131466-1|CAA10376.1| 332|Homo sapiens BCR/ABL (major breakpoi... 53 5e-06
AF113911-1|AAD04633.1| 359|Homo sapiens BCR-ABL minor breakpoin... 53 5e-06
AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine le... 53 5e-06
Z29630-1|CAA82737.1| 612|Homo sapiens protein-tyrosine kinase p... 52 7e-06
L28824-1|AAA36526.1| 635|Homo sapiens protein tyrosine kinase p... 52 7e-06
BT007277-1|AAP35941.1| 304|Homo sapiens v-crk sarcoma virus CT1... 52 7e-06
BC011399-1|AAH11399.1| 612|Homo sapiens SYK protein protein. 52 7e-06
BC009837-1|AAH09837.1| 204|Homo sapiens v-crk sarcoma virus CT1... 52 7e-06
BC008506-1|AAH08506.1| 304|Homo sapiens v-crk sarcoma virus CT1... 52 7e-06
BC002962-1|AAH02962.1| 635|Homo sapiens spleen tyrosine kinase ... 52 7e-06
BC001718-1|AAH01718.1| 304|Homo sapiens v-crk sarcoma virus CT1... 52 7e-06
BC001645-1|AAH01645.1| 635|Homo sapiens spleen tyrosine kinase ... 52 7e-06
AL354862-3|CAI16875.1| 612|Homo sapiens spleen tyrosine kinase ... 52 7e-06
AL354862-2|CAI16876.1| 635|Homo sapiens spleen tyrosine kinase ... 52 7e-06
D10656-1|BAA01505.1| 304|Homo sapiens CRK-II protein. 52 9e-06
Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to S... 51 2e-05
Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to S... 51 2e-05
Z22641-1|CAA80354.1| 459|Homo sapiens a2-chimaerin protein. 51 2e-05
S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)... 51 2e-05
M19722-1|AAA52451.1| 529|Homo sapiens FGR protein. 51 2e-05
M12724-1|AAA52762.1| 306|Homo sapiens FGR protein. 51 2e-05
BC131536-1|AAI31537.1| 1631|Homo sapiens IQ motif containing GTP... 51 2e-05
BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline ... 51 2e-05
BC011393-1|AAH11393.1| 459|Homo sapiens chimerin (chimaerin) 1 ... 51 2e-05
AY253300-1|AAP06954.1| 1631|Homo sapiens IQGAP3 protein. 51 2e-05
AL365274-3|CAH72156.2| 229|Homo sapiens DAB2 interacting protei... 51 2e-05
AL365181-1|CAI13046.1| 1631|Homo sapiens IQ motif containing GTP... 51 2e-05
AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline ... 51 2e-05
AL031729-2|CAI19617.1| 313|Homo sapiens Gardner-Rasheed feline ... 51 2e-05
AK122653-1|BAC85501.1| 1023|Homo sapiens protein. 51 2e-05
AC020596-1|AAY14940.1| 176|Homo sapiens unknown protein. 51 2e-05
AB105103-1|BAC78211.1| 1631|Homo sapiens IQGAP3 protein. 51 2e-05
U15528-2|AAA82880.1| 595|Homo sapiens protein tyrosine phosphat... 51 2e-05
U15528-1|AAA82879.1| 556|Homo sapiens protein tyrosine phosphat... 51 2e-05
U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinem... 51 2e-05
M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein. 51 2e-05
M16038-1|AAA59540.1| 512|Homo sapiens LYN protein. 51 2e-05
M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like ... 51 2e-05
BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein. 51 2e-05
BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein. 51 2e-05
BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 51 2e-05
BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 51 2e-05
BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein. 51 2e-05
BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein. 51 2e-05
X75342-1|CAA53091.1| 596|Homo sapiens Shb protein. 50 3e-05
U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein. 50 3e-05
M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine ... 50 3e-05
L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein. 50 3e-05
DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine le... 50 3e-05
BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein pr... 50 3e-05
BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein. 50 3e-05
BC018646-1|AAH18646.1| 1265|Homo sapiens PLCG2 protein protein. 50 3e-05
BC014561-1|AAH14561.1| 1265|Homo sapiens PLCG2 protein protein. 50 3e-05
BC011772-1|AAH11772.1| 1265|Homo sapiens PLCG2 protein protein. 50 3e-05
BC007565-1|AAH07565.1| 1265|Homo sapiens PLCG2 protein protein. 50 3e-05
AL583849-1|CAH73120.1| 509|Homo sapiens Src homology 2 domain c... 50 3e-05
AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine le... 50 3e-05
AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine le... 50 3e-05
AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine le... 50 3e-05
AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine le... 50 3e-05
AL161448-1|CAH73192.1| 509|Homo sapiens Src homology 2 domain c... 50 3e-05
AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine le... 50 3e-05
AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine le... 50 3e-05
AL138752-4|CAI13876.1| 509|Homo sapiens Src homology 2 domain c... 50 3e-05
AB208914-1|BAD92151.1| 1278|Homo sapiens 1-phosphatidylinositol-... 50 3e-05
M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein. 50 4e-05
Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to S... 50 5e-05
Z33998-1|CAA83965.1| 505|Homo sapiens Protein-Tyrosine Kinase p... 50 5e-05
Y14385-1|CAA74743.1| 1258|Homo sapiens inositol polyphosphate 5-... 50 5e-05
X14034-1|CAA32194.1| 1252|Homo sapiens protein ( Human mRNA for ... 50 5e-05
S76617-1|AAB33265.1| 505|Homo sapiens blk protein. 50 5e-05
M37238-1|AAA60112.1| 1252|Homo sapiens PLC1 protein. 50 5e-05
M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-... 50 5e-05
BC032496-1|AAH32496.1| 482|Homo sapiens FYN oncogene related to... 50 5e-05
BC032413-1|AAH32413.1| 505|Homo sapiens B lymphoid tyrosine kin... 50 5e-05
BC018703-1|AAH18703.1| 599|Homo sapiens Unknown (protein for IM... 50 5e-05
BC007371-1|AAH07371.1| 505|Homo sapiens B lymphoid tyrosine kin... 50 5e-05
AY364256-1|AAQ76815.1| 1252|Homo sapiens phospholipase C gamma 2... 50 5e-05
M16592-1|AAA52644.1| 505|Homo sapiens HCK protein. 49 7e-05
M16591-1|AAA52643.1| 505|Homo sapiens HCK protein. 49 7e-05
M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1 m... 49 7e-05
BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase... 49 7e-05
BC113854-1|AAI13855.2| 504|Homo sapiens HCK protein protein. 49 7e-05
BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase... 49 7e-05
BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase... 49 7e-05
BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase... 49 7e-05
BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarco... 49 7e-05
BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase... 49 7e-05
AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase... 49 7e-05
AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase... 49 7e-05
AL049539-2|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase... 49 7e-05
AL049539-1|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase... 49 7e-05
X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein. 49 9e-05
U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein... 49 9e-05
BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine k... 49 9e-05
AL121829-13|CAC15525.1| 451|Homo sapiens Ptk6 protein. 49 9e-05
U51903-1|AAB37765.1| 1575|Homo sapiens RasGAP-related protein pr... 48 1e-04
AY351902-1|AAQ81291.1| 1071|Homo sapiens testis specific IQ moti... 48 1e-04
AB208856-1|BAD92093.1| 1155|Homo sapiens IQ motif containing GTP... 48 1e-04
BC082982-1|AAH82982.1| 454|Homo sapiens SH2D4A protein protein. 48 2e-04
BC014525-1|AAH14525.2| 338|Homo sapiens SH2D4A protein protein. 48 2e-04
AY190323-1|AAO41715.1| 298|Homo sapiens SH2A protein. 48 2e-04
AL121829-14|CAC15526.1| 488|Homo sapiens protein ( Human DNA se... 48 2e-04
AK024799-1|BAB15010.1| 454|Homo sapiens protein ( Homo sapiens ... 48 2e-04
AK024620-1|BAB14935.1| 272|Homo sapiens protein ( Homo sapiens ... 48 2e-04
AJ865079-1|CAI23831.1| 516|Homo sapiens proto-oncogene tyrosine... 48 2e-04
AB000520-1|BAA22514.1| 632|Homo sapiens APS protein. 48 2e-04
X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human lymphocyt... 47 3e-04
X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA ... 47 3e-04
X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T cell-sp... 47 3e-04
U23852-1|AAC50287.1| 363|Homo sapiens p56lck protein. 47 3e-04
U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific prote... 47 3e-04
M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific prote... 47 3e-04
BC013200-1|AAH13200.1| 539|Homo sapiens LCK protein protein. 47 3e-04
BC007586-1|AAH07586.1| 233|Homo sapiens SHF protein protein. 47 3e-04
AL591042-2|CAI14458.1| 753|Homo sapiens vav 3 oncogene protein. 47 3e-04
AL591042-1|CAI14457.1| 847|Homo sapiens vav 3 oncogene protein. 47 3e-04
AL513206-2|CAH73196.1| 753|Homo sapiens vav 3 oncogene protein. 47 3e-04
AL513206-1|CAH73195.1| 847|Homo sapiens vav 3 oncogene protein. 47 3e-04
AL391235-1|CAH72458.1| 847|Homo sapiens vav 3 oncogene protein. 47 3e-04
AL353892-1|CAI21786.1| 847|Homo sapiens vav 3 oncogene protein. 47 3e-04
AL121991-3|CAI22321.1| 526|Homo sapiens lymphocyte-specific pro... 47 3e-04
AL121991-2|CAI22320.1| 496|Homo sapiens lymphocyte-specific pro... 47 3e-04
AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK pro... 47 3e-04
AF118887-1|AAD20349.1| 847|Homo sapiens VAV-3 protein protein. 47 3e-04
AF118886-1|AAD20348.1| 753|Homo sapiens VAV-3 protein beta isof... 47 3e-04
AF067817-1|AAC79695.1| 847|Homo sapiens VAV-3 protein protein. 47 3e-04
U44403-1|AAC27662.1| 276|Homo sapiens Src-like adapter protein ... 46 6e-04
U30473-1|AAC50357.1| 276|Homo sapiens src-like adapter protein ... 46 6e-04
D89077-1|BAA13758.1| 276|Homo sapiens Src-like adapter protein ... 46 6e-04
CR536537-1|CAG38774.1| 276|Homo sapiens SLA protein. 46 6e-04
BC007042-1|AAH07042.1| 276|Homo sapiens Src-like-adaptor protein. 46 6e-04
BT019994-1|AAV38797.1| 276|Homo sapiens Src-like-adaptor protein. 45 0.001
X82456-1|CAA57833.1| 261|Homo sapiens LIM and SH3 domain protei... 44 0.002
CR542043-1|CAG46840.1| 128|Homo sapiens yndrome); complete cds,... 44 0.002
CR542031-1|CAG46828.1| 128|Homo sapiens yndrome); complete cds,... 44 0.002
BC026314-1|AAH26314.1| 594|Homo sapiens SHC (Src homology 2 dom... 44 0.002
BC020732-1|AAH20732.1| 128|Homo sapiens SH2 domain protein 1A, ... 44 0.002
AL023657-1|CAA19222.1| 128|Homo sapiens SH2D1A protein. 44 0.002
AL022718-4|CAA18777.1| 128|Homo sapiens SH2 domain protein 1A, ... 44 0.002
AF100541-1|AAC79714.1| 125|Homo sapiens SH2 domain protein 1A i... 44 0.002
AF100539-1|AAC79712.1| 76|Homo sapiens SH2 domain protein 1A i... 44 0.002
AF073019-1|AAC62631.1| 128|Homo sapiens T cell signal transduct... 44 0.002
AF072930-1|AAC62630.1| 128|Homo sapiens T cell signal transduct... 44 0.002
U50041-1|AAC50454.1| 1179|Homo sapiens signaling inositol polyph... 44 0.003
D84361-2|BAA12323.1| 474|Homo sapiens p52 isoform of N-Shc prot... 44 0.003
D84361-1|BAA12322.1| 594|Homo sapiens p64 isoform of N-Shc prot... 44 0.003
BC033907-1|AAH33907.1| 630|Homo sapiens SHC (Src homology 2 dom... 44 0.003
AY464565-1|AAR19363.1| 630|Homo sapiens rai-like protein RaLP p... 44 0.003
AY358250-1|AAQ88617.1| 387|Homo sapiens LPAL6438 protein. 44 0.003
AL353150-2|CAI16865.1| 594|Homo sapiens SHC (Src homology 2 dom... 44 0.003
AL160054-4|CAI41366.1| 594|Homo sapiens SHC (Src homology 2 dom... 44 0.003
AF100540-1|AAC79713.1| 58|Homo sapiens SH2 domain protein 1A i... 44 0.003
U28926-1|AAA86528.1| 468|Homo sapiens beta2-chimaerin protein. 44 0.003
U07223-1|AAA16836.1| 466|Homo sapiens beta2-chimaerin protein. 44 0.003
L29126-1|AAA19191.1| 466|Homo sapiens beta2-chimaerin protein. 44 0.003
D29767-1|BAA06171.1| 631|Homo sapiens Tec protein-tyrosine kina... 44 0.003
BC112155-1|AAI12156.1| 468|Homo sapiens chimerin (chimaerin) 2 ... 44 0.003
BC101713-1|AAI01714.1| 631|Homo sapiens tec protein tyrosine ki... 44 0.003
BC101711-1|AAI01712.1| 631|Homo sapiens tec protein tyrosine ki... 44 0.003
BC007206-1|AAH07206.1| 340|Homo sapiens Src homology 2 domain c... 44 0.003
AL390078-1|CAB98202.1| 247|Homo sapiens similar to (NP_033194.1... 44 0.003
AL360254-1|CAB96175.1| 392|Homo sapiens SCK protein. 44 0.003
AK055673-1|BAB70981.1| 340|Homo sapiens protein ( Homo sapiens ... 44 0.003
AK026432-1|BAB15482.1| 505|Homo sapiens protein ( Homo sapiens ... 44 0.003
AC004417-1|AAC06177.1| 175|Homo sapiens unknown protein. 44 0.003
AB001451-1|BAA25798.1| 540|Homo sapiens Sck protein. 44 0.003
Y09847-1|CAA70977.1| 583|Homo sapiens shc p66 protein. 43 0.004
X68148-1|CAA48251.1| 473|Homo sapiens SHC transforming protein ... 43 0.004
U92715-1|AAC39777.1| 825|Homo sapiens breast cancer antiestroge... 43 0.004
U73377-1|AAB49972.1| 583|Homo sapiens p66shc protein. 43 0.004
BC117210-1|AAI17211.1| 495|Homo sapiens Src homology 2 domain c... 43 0.004
BC039895-1|AAH39895.1| 825|Homo sapiens breast cancer anti-estr... 43 0.004
BC033925-1|AAH33925.1| 369|Homo sapiens SHC1 protein protein. 43 0.004
BC014158-1|AAH14158.1| 474|Homo sapiens SHC (Src homology 2 dom... 43 0.004
AL451085-17|CAI13254.1| 384|Homo sapiens SHC (Src homology 2 do... 43 0.004
AL451085-14|CAI13250.1| 583|Homo sapiens SHC (Src homology 2 do... 43 0.004
AL451085-13|CAI13249.1| 473|Homo sapiens SHC (Src homology 2 do... 43 0.004
AL451085-12|CAI13251.1| 584|Homo sapiens SHC (Src homology 2 do... 43 0.004
AL451085-11|CAI13248.1| 474|Homo sapiens SHC (Src homology 2 do... 43 0.004
AL359820-1|CAH73975.1| 825|Homo sapiens breast cancer anti-estr... 43 0.004
AL162591-2|CAH72851.1| 495|Homo sapiens Src homology 2 domain c... 43 0.004
AL109613-2|CAI18951.1| 734|Homo sapiens breast cancer anti-estr... 43 0.004
AL109613-1|CAI18950.1| 825|Homo sapiens breast cancer anti-estr... 43 0.004
AK074067-1|BAB84893.1| 309|Homo sapiens FLJ00138 protein protein. 43 0.004
AF124250-1|AAD28245.1| 825|Homo sapiens SH2-containing protein ... 43 0.004
BC053878-1|AAH53878.1| 619|Homo sapiens zeta-chain (TCR) associ... 43 0.006
BC039039-1|AAH39039.1| 493|Homo sapiens ZAP70 protein protein. 43 0.006
AF100543-1|AAC79716.1| 62|Homo sapiens SH2 domain protein 1A i... 43 0.006
AC016699-1|AAX93187.1| 493|Homo sapiens unknown protein. 43 0.006
L33075-1|AAA59187.1| 1657|Homo sapiens ras GTPase-activating-lik... 42 0.008
D29640-1|BAA06123.2| 1678|Homo sapiens KIAA0051 protein. 42 0.008
BC139731-1|AAI39732.1| 1657|Homo sapiens IQ motif containing GTP... 42 0.008
X98429-1|CAA67071.1| 1188|Homo sapiens inositol polyphosphate 5-... 42 0.010
U84400-1|AAB49680.1| 1189|Homo sapiens SH2 containing inositol-5... 42 0.010
U57650-1|AAB53573.1| 1188|Homo sapiens SH2-containing inositol 5... 42 0.010
U53470-1|AAD00081.1| 1189|Homo sapiens signaling inositol polyph... 42 0.010
BC113582-1|AAI13583.1| 1188|Homo sapiens inositol polyphosphate-... 42 0.010
BC113580-1|AAI13581.1| 1188|Homo sapiens inositol polyphosphate-... 42 0.010
BC099920-1|AAH99920.1| 1188|Homo sapiens inositol polyphosphate-... 42 0.010
BC026233-1|AAH26233.1| 64|Homo sapiens LOC400581 protein protein. 42 0.010
X83931-1|CAA58783.1| 539|Homo sapiens VAV protein. 42 0.013
BC018706-1|AAH18706.1| 480|Homo sapiens TNS4 protein protein. 42 0.013
BC013361-1|AAH13361.2| 790|Homo sapiens VAV1 protein protein. 42 0.013
AK027856-1|BAB55413.1| 480|Homo sapiens protein ( Homo sapiens ... 42 0.013
AF417488-1|AAN32666.1| 715|Homo sapiens C-terminal tensin-like ... 42 0.013
AF030227-1|AAC25011.1| 845|Homo sapiens vav protein protein. 42 0.013
BC032365-1|AAH32365.1| 860|Homo sapiens SH2 domain containing 3... 41 0.018
BC027962-1|AAH27962.1| 703|Homo sapiens SH2D3C protein protein. 41 0.018
AY358440-1|AAQ89948.1| 703|Homo sapiens NSP3 protein. 41 0.018
AY358089-1|AAQ88456.1| 688|Homo sapiens NSP3 protein. 41 0.018
AL162586-7|CAI39766.1| 860|Homo sapiens SH2 domain containing 3... 41 0.018
AL162586-4|CAI39763.1| 703|Homo sapiens SH2 domain containing 3... 41 0.018
AL162586-3|CAI39762.1| 324|Homo sapiens SH2 domain containing 3... 41 0.018
AL162586-2|CAI39761.1| 702|Homo sapiens SH2 domain containing 3... 41 0.018
AL162586-1|CAI39760.1| 196|Homo sapiens SH2 domain containing 3... 41 0.018
AL162426-7|CAI41182.1| 860|Homo sapiens SH2 domain containing 3... 41 0.018
AL162426-4|CAI41179.1| 703|Homo sapiens SH2 domain containing 3... 41 0.018
AL162426-3|CAI41178.1| 324|Homo sapiens SH2 domain containing 3... 41 0.018
AL162426-2|CAI41177.1| 702|Homo sapiens SH2 domain containing 3... 41 0.018
AL162426-1|CAI41176.1| 196|Homo sapiens SH2 domain containing 3... 41 0.018
AF124251-1|AAD28246.1| 703|Homo sapiens SH2-containing protein ... 41 0.018
BC012460-1|AAH12460.1| 261|Homo sapiens LASP1 protein protein. 40 0.031
X80907-1|CAA56868.1| 728|Homo sapiens p85 beta subunit of phosp... 40 0.041
D43772-1|BAA07827.1| 532|Homo sapiens GRB-7 SH2 domain protein ... 40 0.041
CR542079-1|CAG46876.1| 350|Homo sapiens PLEK protein. 40 0.041
CR542056-1|CAG46853.1| 350|Homo sapiens PLEK protein. 40 0.041
BT006686-1|AAP35332.1| 532|Homo sapiens growth factor receptor-... 40 0.041
BC090249-1|AAH90249.1| 728|Homo sapiens phosphoinositide-3-kina... 40 0.041
BC070082-1|AAH70082.1| 728|Homo sapiens phosphoinositide-3-kina... 40 0.041
BC067117-1|AAH67117.1| 380|Homo sapiens SH2D4A protein protein. 40 0.041
BC042041-1|AAH42041.1| 261|Homo sapiens Src-like-adaptor 2 prot... 40 0.041
BC018549-1|AAH18549.1| 350|Homo sapiens pleckstrin protein. 40 0.041
BC014170-1|AAH14170.2| 324|Homo sapiens PIK3R2 protein protein. 40 0.041
BC011917-1|AAH11917.2| 388|Homo sapiens PIK3R2 protein protein. 40 0.041
BC006535-1|AAH06535.1| 532|Homo sapiens growth factor receptor-... 40 0.041
AL050318-2|CAI23504.1| 261|Homo sapiens Src-like-adaptor 2 prot... 40 0.041
AL031662-2|CAI21397.1| 261|Homo sapiens Src-like-adaptor 2 prot... 40 0.041
AK222870-1|BAD96590.1| 532|Homo sapiens growth factor receptor-... 40 0.041
AK222849-1|BAD96569.1| 532|Homo sapiens growth factor receptor-... 40 0.041
AK025645-1|BAB15201.1| 261|Homo sapiens protein ( Homo sapiens ... 40 0.041
AF326353-1|AAL29204.1| 261|Homo sapiens Src-like adapter protei... 40 0.041
AF290985-1|AAL38197.1| 261|Homo sapiens Src-like adaptor protei... 40 0.041
AF274875-1|AAG25938.1| 532|Homo sapiens growth factor receptor-... 40 0.041
AC015969-2|AAX93121.1| 350|Homo sapiens unknown protein. 40 0.041
AC007192-2|AAD22671.1| 728|Homo sapiens P85B_HUMAN protein. 40 0.041
AB208967-1|BAD92204.1| 308|Homo sapiens PLEK protein variant pr... 40 0.041
AB008789-1|BAA29059.1| 532|Homo sapiens grb7 protein protein. 40 0.041
BC025237-1|AAH25237.1| 352|Homo sapiens hematopoietic SH2 domai... 40 0.054
BC018906-1|AAH18906.1| 456|Homo sapiens B-cell linker protein. 40 0.054
AY319652-1|AAQ81285.1| 352|Homo sapiens ALX protein. 40 0.054
AK027792-1|BAB55372.1| 352|Homo sapiens protein ( Homo sapiens ... 40 0.054
AF180756-2|AAF20383.1| 433|Homo sapiens B cell linker protein B... 40 0.054
AF180756-1|AAF20382.1| 456|Homo sapiens B cell linker protein B... 40 0.054
AF068181-1|AAC39937.1| 433|Homo sapiens B cell linker protein B... 40 0.054
AF068180-1|AAC39936.1| 456|Homo sapiens B cell linker protein B... 40 0.054
X07743-1|CAA30564.1| 350|Homo sapiens protein ( Human mRNA for ... 39 0.072
BC053671-1|AAH53671.1| 1056|Homo sapiens SH3RF1 protein protein. 39 0.072
AB040927-1|BAA96018.1| 638|Homo sapiens KIAA1494 protein protein. 39 0.072
Y16241-1|CAA76130.1| 1014|Homo sapiens nebulette protein. 39 0.095
BC126134-1|AAI26135.1| 270|Homo sapiens nebulette protein. 39 0.095
BC126132-1|AAI26133.1| 270|Homo sapiens nebulette protein. 39 0.095
BC110453-1|AAI10454.1| 1014|Homo sapiens nebulette protein. 39 0.095
AL731547-1|CAI15775.1| 270|Homo sapiens nebulette protein. 39 0.095
AL359175-1|CAH71371.1| 270|Homo sapiens nebulette protein. 39 0.095
AL157398-4|CAC19642.1| 1014|Homo sapiens nebulette protein. 39 0.095
AL157398-1|CAI41189.1| 270|Homo sapiens nebulette protein. 39 0.095
AK096540-1|BAC04812.1| 234|Homo sapiens protein ( Homo sapiens ... 39 0.095
AJ580772-1|CAE45323.1| 270|Homo sapiens LIM-nebulette protein. 39 0.095
AF100542-1|AAC79715.1| 76|Homo sapiens SH2 domain protein 1A i... 39 0.095
AF047368-1|AAF24858.1| 1011|Homo sapiens nebulette protein. 39 0.095
AB209311-1|BAD92548.1| 345|Homo sapiens nebulette non-muscle is... 39 0.095
S65186-1|AAB28072.2| 620|Homo sapiens EMT protein. 38 0.13
L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein. 38 0.13
D13720-1|BAA02873.1| 620|Homo sapiens ITK protein. 38 0.13
BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell ki... 38 0.13
BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell ki... 38 0.13
AY763100-1|AAV34675.1| 371|Homo sapiens SH2 domain containing a... 38 0.13
AY763098-1|AAV34673.1| 361|Homo sapiens SH2 domain containing a... 38 0.13
AB209622-1|BAD92859.1| 376|Homo sapiens IL2-inducible T-cell ki... 38 0.13
X83957-1|CAA58788.1| 6669|Homo sapiens nebulin protein. 38 0.17
X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein. 38 0.17
X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein. 38 0.17
U35637-1|AAB02622.1| 3007|Homo sapiens nebulin protein. 38 0.17
S76992-1|AAB34377.1| 878|Homo sapiens VAV2 protein. 38 0.17
BX640754-1|CAE45861.1| 801|Homo sapiens hypothetical protein pr... 38 0.17
BC132967-1|AAI32968.1| 839|Homo sapiens vav 2 oncogene protein. 38 0.17
BC132965-1|AAI32966.1| 839|Homo sapiens vav 2 oncogene protein. 38 0.17
BC128448-1|AAI28449.1| 474|Homo sapiens VAV2 protein protein. 38 0.17
BC063136-1|AAH63136.1| 538|Homo sapiens NEB protein protein. 38 0.17
BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene... 38 0.17
BC033187-1|AAH33187.1| 369|Homo sapiens VAV2 protein protein. 38 0.17
AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes va... 38 0.17
AM180334-1|CAJ55328.1| 433|Homo sapiens B-cell linker protein p... 38 0.17
AM180333-1|CAJ55327.1| 433|Homo sapiens B-cell linker protein p... 38 0.17
AL590710-7|CAI12279.1| 878|Homo sapiens vav 2 oncogene protein. 38 0.17
AL590710-6|CAI12278.1| 868|Homo sapiens vav 2 oncogene protein. 38 0.17
AL590710-5|CAI12280.1| 839|Homo sapiens vav 2 oncogene protein. 38 0.17
AL451085-8|CAI13245.1| 296|Homo sapiens SHC (Src homology 2 dom... 38 0.17
AL445931-3|CAI13723.1| 868|Homo sapiens vav 2 oncogene protein. 38 0.17
AL445931-2|CAI13722.1| 878|Homo sapiens vav 2 oncogene protein. 38 0.17
AL445931-1|CAI13724.1| 839|Homo sapiens vav 2 oncogene protein. 38 0.17
AL357934-3|CAI15781.1| 868|Homo sapiens vav 2 oncogene protein. 38 0.17
AL357934-2|CAI15783.1| 878|Homo sapiens vav 2 oncogene protein. 38 0.17
AL357934-1|CAI15782.1| 839|Homo sapiens vav 2 oncogene protein. 38 0.17
AL049924-1|CAB43208.1| 540|Homo sapiens hypothetical protein pr... 38 0.17
AK056994-1|BAB71337.1| 500|Homo sapiens protein ( Homo sapiens ... 38 0.17
AK027488-1|BAB55148.1| 426|Homo sapiens protein ( Homo sapiens ... 38 0.17
AF227969-1|AAF73914.1| 683|Homo sapiens SH2-B gamma signaling p... 38 0.17
AF227968-1|AAF73913.1| 671|Homo sapiens SH2-B beta signaling pr... 38 0.17
AF227967-1|AAF73912.1| 756|Homo sapiens SH2-B alpha signaling p... 38 0.17
AF117675-1|AAD20347.1| 977|Homo sapiens nebulin protein. 38 0.17
AC009497-1|AAY14651.1| 2802|Homo sapiens unknown protein. 38 0.17
AB208849-1|BAD92086.1| 377|Homo sapiens SHC (Src homology 2 dom... 38 0.17
AB037720-1|BAA92537.1| 730|Homo sapiens KIAA1299 protein protein. 38 0.17
D88532-1|BAA13636.1| 461|Homo sapiens p55pik protein. 38 0.22
BX537388-1|CAD97630.1| 494|Homo sapiens hypothetical protein pr... 38 0.22
BC021622-1|AAH21622.1| 461|Homo sapiens phosphoinositide-3-kina... 38 0.22
BC012107-1|AAH12107.1| 389|Homo sapiens SH2 domain protein 2A p... 38 0.22
BC005381-1|AAH05381.1| 283|Homo sapiens Unknown (protein for IM... 38 0.22
AL590666-2|CAI16337.1| 389|Homo sapiens SH2 domain protein 2A p... 38 0.22
AL590666-1|CAI16336.1| 371|Homo sapiens SH2 domain protein 2A p... 38 0.22
AL358075-3|CAI21703.1| 402|Homo sapiens phosphoinositide-3-kina... 38 0.22
AL358075-2|CAI21702.1| 461|Homo sapiens phosphoinositide-3-kina... 38 0.22
AL358075-1|CAI21701.1| 206|Homo sapiens phosphoinositide-3-kina... 38 0.22
AL158169-2|CAH70008.1| 371|Homo sapiens SH2 domain protein 2A p... 38 0.22
>M23379-1|AAA52517.1| 1047|Homo sapiens GTPase-activating protein
protein.
Length = 1047
Score = 725 bits (1793), Expect = 0.0
Identities = 376/879 (42%), Positives = 550/879 (62%), Gaps = 24/879 (2%)
Query: 60 APPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGI-NHFRITA 118
APP +WYHG+LDR +EERL A K GSYL+RESDR+PGS+VLS+L + + NHFRI A
Sbjct: 175 APPTNQWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIA 234
Query: 119 VCGDYYIGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMP 178
+CGDYYIGGR+F SL++L+G+YSH S LLK E+L D++RV AILPYTK+P
Sbjct: 235 MCGDYYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEPVEDRRRVRAILPYTKVP 294
Query: 179 DTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHP 238
DTDE++F KGD+F VHN++ DGW+WVT RT EQG+I +LVE++ DP+ WFH
Sbjct: 295 DTDEISFLKGDMFIVHNELEDGWMWVTNLRTDEQGLIVEDLVEEVGREEDPHEGKIWFHG 354
Query: 239 NCTKSEAVDMLVKAGPG-SFLVRPSDNSPGDYSLFFHINNQIQRFRI-EKKGVRYLMGGR 296
+K EA ++L+ G SFLVRPSDN+PGDYSL+F N IQRF+I +++MGGR
Sbjct: 355 KISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKICPTPNNQFMMGGR 414
Query: 297 TFECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQSTTGAAAEKIYATLR-ECRDQI 355
+ + +I+ YRKEQIVEG+ L +P+ + + G ++IY T+R + +D
Sbjct: 415 YYNSIGDIIDHYRKEQIVEGYYLKEPVPMQDQEQVLNDTVDG---KEIYNTIRRKTKDAF 471
Query: 356 GLKKTKGIKHYGYLNKKSDKGAKKWKPLYCVLLQEGTDTHLYFYDSPKR-TKPKGLIDLS 414
K I GYL KK KG K+WK LY +L EG+D L +++S KR TKPKGLIDLS
Sbjct: 472 ----YKNIVKKGYLLKKG-KG-KRWKNLYFIL--EGSDAQLIYFESEKRATKPKGLIDLS 523
Query: 415 CAYLYQVHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARH 474
+Y VH+SL+ + CFQ+V + + A T + W++ L+ C +++
Sbjct: 524 VCSVYVVHDSLFGRPNCFQIVVQHFSEEHYIFYFAGETPEQAEDWMKGLQAFCNLRKSSP 583
Query: 475 QCKVGRVSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDPHWXXXXX 534
R+ V L + AH+LP + P+ + L + VA+T R +P W
Sbjct: 584 GTSNKRLRQVSSLVLHIEEAHKLPVKHFTNPYCNIYLNSVQVAKTHAREGQNPVWSEEFV 643
Query: 535 XXXMPPDVTSLTITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPIG--EW 592
+PPD+ IT+ N K+ K+ ++ + +L+ L G +EW+ L P+ E
Sbjct: 644 FDDLPPDINRFEITLSNKTKKSKDPDILFMRCQLSRLQKGHATDEWFLLSSHIPLKGIEP 703
Query: 593 GSLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRTDRQPLATSVLNTFAEC 652
GSLR+R RY E +MP EEY+ ++L+L+ + V AL+ +C DR LA+ +L F
Sbjct: 704 GSLRVRARYSMEKIMPEEEYSEFKELILQKELHVVYALSHVCGQDRTLLASILLRIFLHE 763
Query: 653 GRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLID 712
+ L L E++ E + TLFR +LA+ +++++M+A F+ A+ ++I K+++
Sbjct: 764 KLESLLLCTLNDREISMEDEATTLFRATTLASTLMEQYMKATATQFVHHALKDSILKIME 823
Query: 713 SKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVA 772
SKQ+ EL+P+K++ +D N LL IL ++ IF + E P +RY+ GCLQ++
Sbjct: 824 SKQSCELSPSKLEKNEDVNTNLTHLLNILSELVEKIFMASEILPPTLRYIYGCLQKSVQH 883
Query: 773 KWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANL 832
KWP +RTRVVSGF+FLRLICPA++ PR + ++ +P P A R+L++VAK +QNLANL
Sbjct: 884 KWPTNTTMRTRVVSGFVFLRLICPAILNPRMFNIISDSPSPIAARTLILVAKSVQNLANL 943
Query: 833 VEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHI 892
VEFGAKEPYME VNPFI NK RM++FLD+L NVP+ ++ +S +++++LA LH I
Sbjct: 944 VEFGAKEPYMEGVNPFIKSNKHRMIMFLDELGNVPELPDTTEHSRT--DLSRDLAALHEI 1001
Query: 893 CVAHLTELQGLAK----NQPAIRKLVTVTEMLTKHKQKY 927
CVAH EL+ L+ Q ++KL+ +TE+L + + +Y
Sbjct: 1002 CVAHSDELRTLSNERGAQQHVLKKLLAITELLQQKQNQY 1040
>BC033015-1|AAH33015.1| 1047|Homo sapiens RAS p21 protein activator
(GTPase activating protein) 1 protein.
Length = 1047
Score = 725 bits (1793), Expect = 0.0
Identities = 376/879 (42%), Positives = 550/879 (62%), Gaps = 24/879 (2%)
Query: 60 APPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGI-NHFRITA 118
APP +WYHG+LDR +EERL A K GSYL+RESDR+PGS+VLS+L + + NHFRI A
Sbjct: 175 APPTNQWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIA 234
Query: 119 VCGDYYIGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMP 178
+CGDYYIGGR+F SL++L+G+YSH S LLK E+L D++RV AILPYTK+P
Sbjct: 235 MCGDYYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEPVEDRRRVRAILPYTKVP 294
Query: 179 DTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHP 238
DTDE++F KGD+F VHN++ DGW+WVT RT EQG+I +LVE++ DP+ WFH
Sbjct: 295 DTDEISFLKGDMFIVHNELEDGWMWVTNLRTDEQGLIVEDLVEEVGREEDPHEGKIWFHG 354
Query: 239 NCTKSEAVDMLVKAGPG-SFLVRPSDNSPGDYSLFFHINNQIQRFRI-EKKGVRYLMGGR 296
+K EA ++L+ G SFLVRPSDN+PGDYSL+F N IQRF+I +++MGGR
Sbjct: 355 KISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKICPTPNNQFMMGGR 414
Query: 297 TFECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQSTTGAAAEKIYATLR-ECRDQI 355
+ + +I+ YRKEQIVEG+ L +P+ + + G ++IY T+R + +D
Sbjct: 415 YYNSIGDIIDHYRKEQIVEGYYLKEPVPMQDQEQVLNDTVDG---KEIYNTIRRKTKDAF 471
Query: 356 GLKKTKGIKHYGYLNKKSDKGAKKWKPLYCVLLQEGTDTHLYFYDSPKR-TKPKGLIDLS 414
K I GYL KK KG K+WK LY +L EG+D L +++S KR TKPKGLIDLS
Sbjct: 472 ----YKNIVKKGYLLKKG-KG-KRWKNLYFIL--EGSDAQLIYFESEKRATKPKGLIDLS 523
Query: 415 CAYLYQVHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARH 474
+Y VH+SL+ + CFQ+V + + A T + W++ L+ C +++
Sbjct: 524 VCSVYVVHDSLFGRPNCFQIVVQHFSEEHYIFYFAGETPEQAEDWMKGLQAFCNLRKSSP 583
Query: 475 QCKVGRVSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDPHWXXXXX 534
R+ V L + AH+LP + P+ + L + VA+T R +P W
Sbjct: 584 GTSNKRLRQVSSLVLHIEEAHKLPVKHFTNPYCNIYLNSVQVAKTHAREGQNPVWSEEFV 643
Query: 535 XXXMPPDVTSLTITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPIG--EW 592
+PPD+ IT+ N K+ K+ ++ + +L+ L G +EW+ L P+ E
Sbjct: 644 FDDLPPDINRFEITLSNKTKKSKDPDILFMRCQLSRLQKGHATDEWFLLSSHIPLKGIEP 703
Query: 593 GSLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRTDRQPLATSVLNTFAEC 652
GSLR+R RY E +MP EEY+ ++L+L+ + V AL+ +C DR LA+ +L F
Sbjct: 704 GSLRVRARYSMEKIMPEEEYSEFKELILQKELHVVYALSHVCGQDRTLLASILLRIFLHE 763
Query: 653 GRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLID 712
+ L L E++ E + TLFR +LA+ +++++M+A F+ A+ ++I K+++
Sbjct: 764 KLESLLLCTLNDREISMEDEATTLFRATTLASTLMEQYMKATATQFVHHALKDSILKIME 823
Query: 713 SKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVA 772
SKQ+ EL+P+K++ +D N LL IL ++ IF + E P +RY+ GCLQ++
Sbjct: 824 SKQSCELSPSKLEKNEDVNTNLTHLLNILSELVEKIFMASEILPPTLRYIYGCLQKSVQH 883
Query: 773 KWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANL 832
KWP +RTRVVSGF+FLRLICPA++ PR + ++ +P P A R+L++VAK +QNLANL
Sbjct: 884 KWPTNTTMRTRVVSGFVFLRLICPAILNPRMFNIISDSPSPIAARTLILVAKSVQNLANL 943
Query: 833 VEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHI 892
VEFGAKEPYME VNPFI NK RM++FLD+L NVP+ ++ +S +++++LA LH I
Sbjct: 944 VEFGAKEPYMEGVNPFIKSNKHRMIMFLDELGNVPELPDTTEHSRT--DLSRDLAALHEI 1001
Query: 893 CVAHLTELQGLAK----NQPAIRKLVTVTEMLTKHKQKY 927
CVAH EL+ L+ Q ++KL+ +TE+L + + +Y
Sbjct: 1002 CVAHSDELRTLSNERGAQQHVLKKLLAITELLQQKQNQY 1040
>M23612-1|AAA35865.1| 870|Homo sapiens GTPase-activating protein
protein.
Length = 870
Score = 718 bits (1774), Expect = 0.0
Identities = 373/873 (42%), Positives = 546/873 (62%), Gaps = 24/873 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGI-NHFRITAVCGDYY 124
WYHG+LDR +EERL A K GSYL+RESDR+PGS+VLS+L + + NHFRI A+CGDYY
Sbjct: 4 WYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDYY 63
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTDELT 184
IGGR+F SL++L+G+YSH S LLK E+L D++RV AILPYTK+PDTDE++
Sbjct: 64 IGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEPVEDRRRVRAILPYTKVPDTDEIS 123
Query: 185 FQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNCTKSE 244
F KGD+F VHN++ DGW+WVT RT EQG+I +LVE++ DP+ WFH +K E
Sbjct: 124 FLKGDMFIVHNELEDGWMWVTNLRTDEQGLIVEDLVEEVGREEDPHEGKIWFHGKISKQE 183
Query: 245 AVDMLVKAGPG-SFLVRPSDNSPGDYSLFFHINNQIQRFRI-EKKGVRYLMGGRTFECLD 302
A ++L+ G SFLVRPSDN+PGDYSL+F N IQRF+I +++MGGR + +
Sbjct: 184 AYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKICPTPNNQFMMGGRYYNSIG 243
Query: 303 AVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQSTTGAAAEKIYATLR-ECRDQIGLKKTK 361
+I+ YRKEQIVEG+ L +P+ + + G ++IY T+R + +D K
Sbjct: 244 DIIDHYRKEQIVEGYYLKEPVPMQDQEQVLNDTVDG---KEIYNTIRRKTKDAF----YK 296
Query: 362 GIKHYGYLNKKSDKGAKKWKPLYCVLLQEGTDTHLYFYDSPKR-TKPKGLIDLSCAYLYQ 420
I GYL KK KG K+WK LY +L EG+D L +++S KR TKPKGLIDLS +Y
Sbjct: 297 NIVKKGYLLKKG-KG-KRWKNLYFIL--EGSDAQLIYFESEKRATKPKGLIDLSVCSVYV 352
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
VH+SL+ + CFQ+V + + A T + W++ L+ C +++ R
Sbjct: 353 VHDSLFGRPNCFQIVVQHFSEEHYIFYFAGETPEQAEDWMKGLQAFCNLRKSSPGTSNKR 412
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDPHWXXXXXXXXMPP 540
+ V L + AH+LP + P+ + L + VA+T R +P W +PP
Sbjct: 413 LRQVSSLVLHIEEAHKLPVKHFTNPYCNIYLNSVQVAKTHAREGQNPVWSEEFVFDDLPP 472
Query: 541 DVTSLTITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPIG--EWGSLRLR 598
D+ IT+ N K+ K+ ++ + +L+ L G +EW+ L P+ E GSLR+R
Sbjct: 473 DINRFEITLSNKTKKSKDPDILFMRCQLSRLQKGHATDEWFLLSSHIPLKGIEPGSLRVR 532
Query: 599 IRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRTDRQPLATSVLNTFAECGRGAEL 658
RY E +MP EEY+ ++L+L+ + V AL+ +C DR LA+ +L F + L
Sbjct: 533 ARYSMEKIMPEEEYSEFKELILQKELHVVYALSHVCGQDRTLLASILLRIFLHEKLESLL 592
Query: 659 ARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAE 718
L E++ E + TLFR +LA+ +++++M+A F+ A+ ++I K+++SKQ+ E
Sbjct: 593 LCTLNDREISMEDEATTLFRATTLASTLMEQYMKATATQFVHHALKDSILKIMESKQSCE 652
Query: 719 LNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNER 778
L+P+K++ +D N LL IL ++ IF + E P +RY+ GCLQ++ KWP
Sbjct: 653 LSPSKLEKNEDVNTNLTHLLNILSELVEKIFMASEILPPTLRYIYGCLQKSVQHKWPTNT 712
Query: 779 FVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAK 838
+RTRVVSGF+FLRLICPA++ PR + ++ +P P A R+L++VAK +QNLANLVEFGAK
Sbjct: 713 TMRTRVVSGFVFLRLICPAILNPRMFNIISDSPSPIAARTLILVAKSVQNLANLVEFGAK 772
Query: 839 EPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHICVAHLT 898
EPYME VNPFI NK RM++FLD+L NVP+ ++ +S +++++LA LH ICVAH
Sbjct: 773 EPYMEGVNPFIKSNKHRMIMFLDELGNVPELPDTTEHSRT--DLSRDLAALHEICVAHSD 830
Query: 899 ELQGLAK----NQPAIRKLVTVTEMLTKHKQKY 927
EL+ L+ Q ++KL+ +TE+L + + +Y
Sbjct: 831 ELRTLSNERGAQQHVLKKLLAITELLQQKQNQY 863
>AB209106-1|BAD92343.1| 871|Homo sapiens RAS p21 protein activator
1 isoform 1 variant protein.
Length = 871
Score = 525 bits (1296), Expect = e-148
Identities = 278/673 (41%), Positives = 410/673 (60%), Gaps = 18/673 (2%)
Query: 60 APPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGI-NHFRITA 118
APP +WYHG+LDR +EERL A K GSYL+RESDR+PGS+VLS+L + + NHFRI A
Sbjct: 208 APPTNQWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIA 267
Query: 119 VCGDYYIGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMP 178
+CGDYYIGGR+F SL++L+G+YSH S LLK E+L D++RV AILPYTK+P
Sbjct: 268 MCGDYYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEPVEDRRRVRAILPYTKVP 327
Query: 179 DTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHP 238
DTDE++F KGD+F VHN++ DGW+WVT RT EQG+I +LVE++ DP+ WFH
Sbjct: 328 DTDEISFLKGDMFIVHNELEDGWMWVTNLRTDEQGLIVEDLVEEVGREEDPHEGKIWFHG 387
Query: 239 NCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRI-EKKGVRYLMGGR 296
+K EA ++L+ G SFLVRPSDN+PGDYSL+F N IQRF+I +++MGGR
Sbjct: 388 KISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKICPTPNNQFMMGGR 447
Query: 297 TFECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQSTTGAAAEKIYATL-RECRDQI 355
+ + +I+ YRKEQIVEG+ L +P+ + + Q ++IY T+ R+ +D
Sbjct: 448 YYNSIGDIIDHYRKEQIVEGYYLKEPVPMQD---QEQVLNDTVDGKEIYNTIRRKTKDAF 504
Query: 356 GLKKTKGIKHYGYLNKKSDKGAKKWKPLYCVLLQEGTDTHLYFYDSPKR-TKPKGLIDLS 414
K I GYL KK KG K+WK LY +L EG+D L +++S KR TKPKGLIDLS
Sbjct: 505 ----YKNIVKKGYLLKKG-KG-KRWKNLYFIL--EGSDAQLIYFESEKRATKPKGLIDLS 556
Query: 415 CAYLYQVHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARH 474
+Y VH+SL+ + CFQ+V + + A T + W++ L+ C +++
Sbjct: 557 VCSVYVVHDSLFGRPNCFQIVVQHFSEEHYIFYFAGETPEQAEDWMKGLQAFCNLRKSSP 616
Query: 475 QCKVGRVSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDPHWXXXXX 534
R+ V L + AH+LP + P+ + L + VA+T R +P W
Sbjct: 617 GTSNKRLRQVSSLVLHIEEAHKLPVKHFTNPYCNIYLNSVQVAKTHAREGQNPVWSEEFV 676
Query: 535 XXXMPPDVTSLTITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPIG--EW 592
+PPD+ IT+ N K+ K+ ++ + +L+ L G +EW+ L P+ E
Sbjct: 677 FDDLPPDINRFEITLSNKTKKSKDPDILFMRCQLSRLQKGHATDEWFLLSSHIPLKGIEP 736
Query: 593 GSLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRTDRQPLATSVLNTFAEC 652
GSLR+R RY E +MP EEY+ ++L+L+ + V AL+ +C DR LA+ +L F
Sbjct: 737 GSLRVRARYSMEKIMPEEEYSEFKELILQKELHVVYALSHVCGQDRTLLASILLRIFLHE 796
Query: 653 GRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLID 712
+ L L E++ E + TLFR +LA+ +++++M+A F+ A+ ++I K+++
Sbjct: 797 KLESLLLCTLNDREISMEDEATTLFRATTLASTLMEQYMKATATQFVHHALKDSILKIME 856
Query: 713 SKQTAELNPTKMD 725
SKQ+ EL+P+K++
Sbjct: 857 SKQSCELSPSKLE 869
>BC020761-1|AAH20761.1| 317|Homo sapiens Unknown (protein for
IMAGE:4733187) protein.
Length = 317
Score = 314 bits (772), Expect = 7e-85
Identities = 160/320 (50%), Positives = 215/320 (67%), Gaps = 11/320 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGI-NHFRITAVCGDYY 124
WYHG+LDR +EERL A K GSYL+RESDR+PGS+VLS+L + + NHFRI A+CGDYY
Sbjct: 4 WYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDYY 63
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTDELT 184
IGGR+F SL++L+G+YSH S LLK E+L D++RV AILPYTK+PDTDE++
Sbjct: 64 IGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEPVEDRRRVRAILPYTKVPDTDEIS 123
Query: 185 FQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNCTKSE 244
F KGD+F VHN++ DGW+WVT RT EQG+I +LVE++ DP+ WFH +K E
Sbjct: 124 FLKGDMFIVHNELEDGWMWVTNLRTDEQGLIVEDLVEEVGREEDPHEGKIWFHGKISKQE 183
Query: 245 AVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRI-EKKGVRYLMGGRTFECLD 302
A ++L+ G SFLVRPSDN+PGDYSL+F N IQRF+I +++MGGR + +
Sbjct: 184 AYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKICPTPNNQFMMGGRYYNSIG 243
Query: 303 AVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQSTTGAAAEKIYATL-RECRDQIGLKKTK 361
+I+ YRKEQIVEG+ L +P+ + + Q ++IY T+ R+ +D K
Sbjct: 244 DIIDHYRKEQIVEGYYLKEPVPMQD---QEQVLNDTVDGKEIYNTIRRKTKDAF----YK 296
Query: 362 GIKHYGYLNKKSDKGAKKWK 381
I GYL K++ K KK K
Sbjct: 297 NIVKKGYLLKEAKKKKKKKK 316
>BC054891-1|AAH54891.1| 313|Homo sapiens RASA1 protein protein.
Length = 313
Score = 313 bits (768), Expect = 2e-84
Identities = 159/317 (50%), Positives = 212/317 (66%), Gaps = 11/317 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGI-NHFRITAVCGDYY 124
WYHG+LDR +EERL A K GSYL+RESDR+PGS+VLS+L + + NHFRI A+CGDYY
Sbjct: 4 WYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDYY 63
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTDELT 184
IGGR+F SL++L+G+YSH S LLK E+L D++RV AILPYTK+PDTDE++
Sbjct: 64 IGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEPVEDRRRVRAILPYTKVPDTDEIS 123
Query: 185 FQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNCTKSE 244
F KGD+F VHN++ DGW+WVT RT EQG+I +LVE++ DP+ WFH +K E
Sbjct: 124 FLKGDMFIVHNELEDGWMWVTNLRTDEQGLIVEDLVEEVGREEDPHEGKIWFHGKISKQE 183
Query: 245 AVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRI-EKKGVRYLMGGRTFECLD 302
A ++L+ G SFLVRPSDN+PGDYSL+F N IQRF+I +++MGGR + +
Sbjct: 184 AYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKICPTPNNQFMMGGRYYNSIG 243
Query: 303 AVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQSTTGAAAEKIYATL-RECRDQIGLKKTK 361
+I+ YRKEQIVEG+ L +P+ + + Q ++IY T+ R+ +D K
Sbjct: 244 DIIDHYRKEQIVEGYYLKEPVPMQD---QEQVLNDTVDGKEIYNTIRRKTKDAF----YK 296
Query: 362 GIKHYGYLNKKSDKGAK 378
I GYL KK K K
Sbjct: 297 NIVKKGYLLKKKKKKKK 313
>BC110611-1|AAI10612.1| 1262|Homo sapiens RASAL2 protein protein.
Length = 1262
Score = 173 bits (422), Expect = 2e-42
Identities = 131/513 (25%), Positives = 247/513 (48%), Gaps = 30/513 (5%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
+H S+ ++FCF++ LS + N+A+E W+E LR P + C+
Sbjct: 246 LHSSILGQDFCFEVTY-----LSGSKCFSCNSASERDKWMENLRRTVQPN--KDNCRRAE 298
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDP-HWXXXXXXXXMP 539
LW+ + A L + + + L ART + D W +P
Sbjct: 299 NVLRLWI----IEAKDLAPK--KKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFFSLP 352
Query: 540 PDVTSLTITVHNT----GKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPI-GEWG- 593
P + S+T+ ++ K+ K + V + I A++ + +E+WYP+ TP G+ G
Sbjct: 353 P-LHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGG 411
Query: 594 -SLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRT-DRQPLATSVLNTFAE 651
S+R++ R+ ++P E+Y + + L + +++ LA ++++
Sbjct: 412 PSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELACALVHILQS 471
Query: 652 CGRGAELARELTCAEVAREGDHKTL-FRGASLATAVLDEFMRAHCKPFLQAAISETIQKL 710
GR + +L +EV R G+H L FR ++AT ++E+++ + +L A+ E I+ L
Sbjct: 472 TGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKAL 531
Query: 711 IDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAA 770
+S + E++P+K S + ++ L M + I S P+ ++ + ++
Sbjct: 532 YESDENCEVDPSKCSS-SELIDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQC 590
Query: 771 VAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLA 830
+ + + + R++S +FLR +CPA++ P + L+Q P R+L ++AK +QNLA
Sbjct: 591 LNRGKQD--ISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLA 648
Query: 831 NLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLH 890
N +FG KE YM +N F+ M FL ++SN PD ++ P + ++ +EL+ LH
Sbjct: 649 NFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISN-PDTISNTPGFDGYIDLGRELSVLH 707
Query: 891 HICVAHLTELQ--GLAKNQPAIRKLVTVTEMLT 921
+ +++L +AK P R L +T+ LT
Sbjct: 708 SLLWEVVSQLDKATVAKLGPLPRVLADITKSLT 740
>AL499617-1|CAH72349.1| 1269|Homo sapiens RAS protein activator like
2 protein.
Length = 1269
Score = 168 bits (409), Expect = 7e-41
Identities = 134/520 (25%), Positives = 249/520 (47%), Gaps = 37/520 (7%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
+H S+ ++FCF++ LS + N+A+E W+E LR P + C+
Sbjct: 246 LHSSILGQDFCFEVTY-----LSGSKCFSCNSASERDKWMENLRRTVQPN--KDNCRRAE 298
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDP-HWXXXXXXXXMP 539
LW+ + A L + + + L ART + D W +P
Sbjct: 299 NVLRLWI----IEAKDLAPK--KKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFFSLP 352
Query: 540 PDVTSLTITVHNT----GKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPI-GEWG- 593
P + S+T+ ++ K+ K + V + I A++ + +E+WYP+ TP G+ G
Sbjct: 353 P-LHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGG 411
Query: 594 -SLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRT-DRQPLATSVLNTFAE 651
S+R++ R+ ++P E+Y + + L + +++ LA ++++
Sbjct: 412 PSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELACALVHILQS 471
Query: 652 CGRGAELARELTCAEVAREGDHKTL-FRGASLATAVLDEFMRAHCKPFLQAAISETIQKL 710
GR + +L +EV R G+H L FR ++AT ++E+++ + +L A+ E I+ L
Sbjct: 472 TGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKAL 531
Query: 711 IDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAA 770
+S + E++P+K S + ++ L M + I S P+ ++ + ++
Sbjct: 532 YESDENCEVDPSKCSS-SELIDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQC 590
Query: 771 VAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLA 830
+ + + + R++S +FLR +CPA++ P + L+Q P R+L ++AK +QNLA
Sbjct: 591 LNRGKQD--ISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLA 648
Query: 831 NLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLH 890
N +FG KE YM +N F+ M FL ++SN PD ++ P + ++ +EL+ LH
Sbjct: 649 NFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISN-PDTISNTPGFDGYIDLGRELSVLH 707
Query: 891 HI---CVAHLTE-----LQG-LAKNQPAIRKLVTVTEMLT 921
+ V+ L + LQ +AK P R L +T+ LT
Sbjct: 708 SLLWEVVSQLDKGENSFLQATVAKLGPLPRVLADITKSLT 747
>AL365357-2|CAI22693.1| 1139|Homo sapiens RAS protein activator like
2 protein.
Length = 1139
Score = 168 bits (409), Expect = 7e-41
Identities = 134/520 (25%), Positives = 249/520 (47%), Gaps = 37/520 (7%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
+H S+ ++FCF++ LS + N+A+E W+E LR P + C+
Sbjct: 116 LHSSILGQDFCFEVTY-----LSGSKCFSCNSASERDKWMENLRRTVQPN--KDNCRRAE 168
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDP-HWXXXXXXXXMP 539
LW+ + A L + + + L ART + D W +P
Sbjct: 169 NVLRLWI----IEAKDLAPK--KKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFFSLP 222
Query: 540 PDVTSLTITVHNT----GKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPI-GEWG- 593
P + S+T+ ++ K+ K + V + I A++ + +E+WYP+ TP G+ G
Sbjct: 223 P-LHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGG 281
Query: 594 -SLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRT-DRQPLATSVLNTFAE 651
S+R++ R+ ++P E+Y + + L + +++ LA ++++
Sbjct: 282 PSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELACALVHILQS 341
Query: 652 CGRGAELARELTCAEVAREGDHKTL-FRGASLATAVLDEFMRAHCKPFLQAAISETIQKL 710
GR + +L +EV R G+H L FR ++AT ++E+++ + +L A+ E I+ L
Sbjct: 342 TGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKAL 401
Query: 711 IDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAA 770
+S + E++P+K S + ++ L M + I S P+ ++ + ++
Sbjct: 402 YESDENCEVDPSKCSS-SELIDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQC 460
Query: 771 VAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLA 830
+ + + + R++S +FLR +CPA++ P + L+Q P R+L ++AK +QNLA
Sbjct: 461 LNRGKQD--ISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLA 518
Query: 831 NLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLH 890
N +FG KE YM +N F+ M FL ++SN PD ++ P + ++ +EL+ LH
Sbjct: 519 NFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISN-PDTISNTPGFDGYIDLGRELSVLH 577
Query: 891 HI---CVAHLTE-----LQG-LAKNQPAIRKLVTVTEMLT 921
+ V+ L + LQ +AK P R L +T+ LT
Sbjct: 578 SLLWEVVSQLDKGENSFLQATVAKLGPLPRVLADITKSLT 617
>AL365357-1|CAI22692.1| 1269|Homo sapiens RAS protein activator like
2 protein.
Length = 1269
Score = 168 bits (409), Expect = 7e-41
Identities = 134/520 (25%), Positives = 249/520 (47%), Gaps = 37/520 (7%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
+H S+ ++FCF++ LS + N+A+E W+E LR P + C+
Sbjct: 246 LHSSILGQDFCFEVTY-----LSGSKCFSCNSASERDKWMENLRRTVQPN--KDNCRRAE 298
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDP-HWXXXXXXXXMP 539
LW+ + A L + + + L ART + D W +P
Sbjct: 299 NVLRLWI----IEAKDLAPK--KKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFFSLP 352
Query: 540 PDVTSLTITVHNT----GKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPI-GEWG- 593
P + S+T+ ++ K+ K + V + I A++ + +E+WYP+ TP G+ G
Sbjct: 353 P-LHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGG 411
Query: 594 -SLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRT-DRQPLATSVLNTFAE 651
S+R++ R+ ++P E+Y + + L + +++ LA ++++
Sbjct: 412 PSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELACALVHILQS 471
Query: 652 CGRGAELARELTCAEVAREGDHKTL-FRGASLATAVLDEFMRAHCKPFLQAAISETIQKL 710
GR + +L +EV R G+H L FR ++AT ++E+++ + +L A+ E I+ L
Sbjct: 472 TGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKAL 531
Query: 711 IDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAA 770
+S + E++P+K S + ++ L M + I S P+ ++ + ++
Sbjct: 532 YESDENCEVDPSKCSS-SELIDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQC 590
Query: 771 VAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLA 830
+ + + + R++S +FLR +CPA++ P + L+Q P R+L ++AK +QNLA
Sbjct: 591 LNRGKQD--ISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLA 648
Query: 831 NLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLH 890
N +FG KE YM +N F+ M FL ++SN PD ++ P + ++ +EL+ LH
Sbjct: 649 NFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISN-PDTISNTPGFDGYIDLGRELSVLH 707
Query: 891 HI---CVAHLTE-----LQG-LAKNQPAIRKLVTVTEMLT 921
+ V+ L + LQ +AK P R L +T+ LT
Sbjct: 708 SLLWEVVSQLDKGENSFLQATVAKLGPLPRVLADITKSLT 747
>AL160281-1|CAH71462.1| 1269|Homo sapiens RAS protein activator like
2 protein.
Length = 1269
Score = 168 bits (409), Expect = 7e-41
Identities = 134/520 (25%), Positives = 249/520 (47%), Gaps = 37/520 (7%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
+H S+ ++FCF++ LS + N+A+E W+E LR P + C+
Sbjct: 246 LHSSILGQDFCFEVTY-----LSGSKCFSCNSASERDKWMENLRRTVQPN--KDNCRRAE 298
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDP-HWXXXXXXXXMP 539
LW+ + A L + + + L ART + D W +P
Sbjct: 299 NVLRLWI----IEAKDLAPK--KKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFFSLP 352
Query: 540 PDVTSLTITVHNT----GKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPI-GEWG- 593
P + S+T+ ++ K+ K + V + I A++ + +E+WYP+ TP G+ G
Sbjct: 353 P-LHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGG 411
Query: 594 -SLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRT-DRQPLATSVLNTFAE 651
S+R++ R+ ++P E+Y + + L + +++ LA ++++
Sbjct: 412 PSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELACALVHILQS 471
Query: 652 CGRGAELARELTCAEVAREGDHKTL-FRGASLATAVLDEFMRAHCKPFLQAAISETIQKL 710
GR + +L +EV R G+H L FR ++AT ++E+++ + +L A+ E I+ L
Sbjct: 472 TGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKAL 531
Query: 711 IDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAA 770
+S + E++P+K S + ++ L M + I S P+ ++ + ++
Sbjct: 532 YESDENCEVDPSKCSS-SELIDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQC 590
Query: 771 VAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLA 830
+ + + + R++S +FLR +CPA++ P + L+Q P R+L ++AK +QNLA
Sbjct: 591 LNRGKQD--ISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLA 648
Query: 831 NLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLH 890
N +FG KE YM +N F+ M FL ++SN PD ++ P + ++ +EL+ LH
Sbjct: 649 NFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISN-PDTISNTPGFDGYIDLGRELSVLH 707
Query: 891 HI---CVAHLTE-----LQG-LAKNQPAIRKLVTVTEMLT 921
+ V+ L + LQ +AK P R L +T+ LT
Sbjct: 708 SLLWEVVSQLDKGENSFLQATVAKLGPLPRVLADITKSLT 747
>AL035702-3|CAI21912.1| 1139|Homo sapiens RAS protein activator like
2 protein.
Length = 1139
Score = 168 bits (409), Expect = 7e-41
Identities = 134/520 (25%), Positives = 249/520 (47%), Gaps = 37/520 (7%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
+H S+ ++FCF++ LS + N+A+E W+E LR P + C+
Sbjct: 116 LHSSILGQDFCFEVTY-----LSGSKCFSCNSASERDKWMENLRRTVQPN--KDNCRRAE 168
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDP-HWXXXXXXXXMP 539
LW+ + A L + + + L ART + D W +P
Sbjct: 169 NVLRLWI----IEAKDLAPK--KKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFFSLP 222
Query: 540 PDVTSLTITVHNT----GKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPI-GEWG- 593
P + S+T+ ++ K+ K + V + I A++ + +E+WYP+ TP G+ G
Sbjct: 223 P-LHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGG 281
Query: 594 -SLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRT-DRQPLATSVLNTFAE 651
S+R++ R+ ++P E+Y + + L + +++ LA ++++
Sbjct: 282 PSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELACALVHILQS 341
Query: 652 CGRGAELARELTCAEVAREGDHKTL-FRGASLATAVLDEFMRAHCKPFLQAAISETIQKL 710
GR + +L +EV R G+H L FR ++AT ++E+++ + +L A+ E I+ L
Sbjct: 342 TGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKAL 401
Query: 711 IDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAA 770
+S + E++P+K S + ++ L M + I S P+ ++ + ++
Sbjct: 402 YESDENCEVDPSKCSS-SELIDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQC 460
Query: 771 VAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLA 830
+ + + + R++S +FLR +CPA++ P + L+Q P R+L ++AK +QNLA
Sbjct: 461 LNRGKQD--ISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLA 518
Query: 831 NLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLH 890
N +FG KE YM +N F+ M FL ++SN PD ++ P + ++ +EL+ LH
Sbjct: 519 NFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISN-PDTISNTPGFDGYIDLGRELSVLH 577
Query: 891 HI---CVAHLTE-----LQG-LAKNQPAIRKLVTVTEMLT 921
+ V+ L + LQ +AK P R L +T+ LT
Sbjct: 578 SLLWEVVSQLDKGENSFLQATVAKLGPLPRVLADITKSLT 617
>AL035702-1|CAI21910.1| 1269|Homo sapiens RAS protein activator like
2 protein.
Length = 1269
Score = 168 bits (409), Expect = 7e-41
Identities = 134/520 (25%), Positives = 249/520 (47%), Gaps = 37/520 (7%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
+H S+ ++FCF++ LS + N+A+E W+E LR P + C+
Sbjct: 246 LHSSILGQDFCFEVTY-----LSGSKCFSCNSASERDKWMENLRRTVQPN--KDNCRRAE 298
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDP-HWXXXXXXXXMP 539
LW+ + A L + + + L ART + D W +P
Sbjct: 299 NVLRLWI----IEAKDLAPK--KKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFFSLP 352
Query: 540 PDVTSLTITVHNT----GKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPI-GEWG- 593
P + S+T+ ++ K+ K + V + I A++ + +E+WYP+ TP G+ G
Sbjct: 353 P-LHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGG 411
Query: 594 -SLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRT-DRQPLATSVLNTFAE 651
S+R++ R+ ++P E+Y + + L + +++ LA ++++
Sbjct: 412 PSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELACALVHILQS 471
Query: 652 CGRGAELARELTCAEVAREGDHKTL-FRGASLATAVLDEFMRAHCKPFLQAAISETIQKL 710
GR + +L +EV R G+H L FR ++AT ++E+++ + +L A+ E I+ L
Sbjct: 472 TGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKAL 531
Query: 711 IDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAA 770
+S + E++P+K S + ++ L M + I S P+ ++ + ++
Sbjct: 532 YESDENCEVDPSKCSS-SELIDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQC 590
Query: 771 VAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLA 830
+ + + + R++S +FLR +CPA++ P + L+Q P R+L ++AK +QNLA
Sbjct: 591 LNRGKQD--ISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLA 648
Query: 831 NLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLH 890
N +FG KE YM +N F+ M FL ++SN PD ++ P + ++ +EL+ LH
Sbjct: 649 NFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISN-PDTISNTPGFDGYIDLGRELSVLH 707
Query: 891 HI---CVAHLTE-----LQG-LAKNQPAIRKLVTVTEMLT 921
+ V+ L + LQ +AK P R L +T+ LT
Sbjct: 708 SLLWEVVSQLDKGENSFLQATVAKLGPLPRVLADITKSLT 747
>AF047711-1|AAD04814.1| 1139|Homo sapiens nGAP protein.
Length = 1139
Score = 168 bits (409), Expect = 7e-41
Identities = 134/520 (25%), Positives = 249/520 (47%), Gaps = 37/520 (7%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
+H S+ ++FCF++ LS + N+A+E W+E LR P + C+
Sbjct: 116 LHSSILGQDFCFEVTY-----LSGSKCFSCNSASERDKWMENLRRTVQPN--KDNCRRAE 168
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDP-HWXXXXXXXXMP 539
LW+ + A L + + + L ART + D W +P
Sbjct: 169 NVLRLWI----IEAKDLAPK--KKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFFSLP 222
Query: 540 PDVTSLTITVHNT----GKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPI-GEWG- 593
P + S+T+ ++ K+ K + V + I A++ + +E+WYP+ TP G+ G
Sbjct: 223 P-LHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGG 281
Query: 594 -SLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRT-DRQPLATSVLNTFAE 651
S+R++ R+ ++P E+Y + + L + +++ LA ++++
Sbjct: 282 PSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELACALVHILQS 341
Query: 652 CGRGAELARELTCAEVAREGDHKTL-FRGASLATAVLDEFMRAHCKPFLQAAISETIQKL 710
GR + +L +EV R G+H L FR ++AT ++E+++ + +L A+ E I+ L
Sbjct: 342 TGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKAL 401
Query: 711 IDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAA 770
+S + E++P+K S + ++ L M + I S P+ ++ + ++
Sbjct: 402 YESDENCEVDPSKCSS-SELIDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQC 460
Query: 771 VAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLA 830
+ + + + R++S +FLR +CPA++ P + L+Q P R+L ++AK +QNLA
Sbjct: 461 LNRGKQD--ISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLA 518
Query: 831 NLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLH 890
N +FG KE YM +N F+ M FL ++SN PD ++ P + ++ +EL+ LH
Sbjct: 519 NFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISN-PDTISNTPGFDGYIDLGRELSVLH 577
Query: 891 HI---CVAHLTE-----LQG-LAKNQPAIRKLVTVTEMLT 921
+ V+ L + LQ +AK P R L +T+ LT
Sbjct: 578 SLLWEVVSQLDKGENSFLQATVAKLGPLPRVLADITKSLT 617
>AK122587-1|BAC56928.1| 749|Homo sapiens FLJ00412 protein protein.
Length = 749
Score = 165 bits (400), Expect = 8e-40
Identities = 142/480 (29%), Positives = 221/480 (46%), Gaps = 26/480 (5%)
Query: 418 LYQVHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCK 477
++ +H SL + CFQ+ + F + A +R WIE LR P Q
Sbjct: 275 IWPLHPSLLGEPHCFQVTWTG----GSRCFSCRSAAERDR-WIEDLRRQFQPTQDN---- 325
Query: 478 VGRVSWVLWLRVRCLTAHRLPARLAPRPHLR--VLLGAAPVARTRPRPSPDP-HWXXXXX 534
V R WL V A LP A P +R + L A +ART PR P W
Sbjct: 326 VEREE--TWLSVWVHEAKGLPRAAAGAPGVRAELWLDGALLARTAPRAGPGQLFWAERFH 383
Query: 535 XXXMPPDVTSLTITVHNTGKRGKESEVAELTIEL--ANLANGEEIEEWYPLVGMTPIGEW 592
+PP L++ + G L +E A A +E W+PL+G P G
Sbjct: 384 FEALPP-ARRLSLRLRGLGPGSAVLGRVALALEELDAPRAPAAGLERWFPLLG-APAG-- 439
Query: 593 GSLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALAD-LCRTDRQPLATSVLNTFAE 651
+LR RIR + V+P E Y L + L AL L ++ LA +++
Sbjct: 440 AALRARIRARRLRVLPSERYKELAEFLTFHYARLCGALEPALPAQAKEELAAAMVRVLRA 499
Query: 652 CGRGAELARELTCAEVAREGDHKTL-FRGASLATAVLDEFMRAHCKPFLQAAISETIQKL 710
GR L +L AE+AR G + L FR +LAT +DE+M+ + +LQ + + +++L
Sbjct: 500 TGRAQALVTDLGTAELARCGGREALLFRENTLATKAIDEYMKLVAQDYLQETLGQVVRRL 559
Query: 711 IDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAA 770
S + E++P+K + + + A L +++ +I S + P + + + A
Sbjct: 560 CASTEDCEVDPSKCPASELPEHQAR-LRNSCEEVFETIIHSYDWFPAELGIVFSSWREAC 618
Query: 771 VAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLA 830
K + R+V +FLRL+CPA++ P + L P P R+L ++AK +QNLA
Sbjct: 619 --KERGSEVLGPRLVCASLFLRLLCPAILAPSLFGLAPDHPAPGPARTLTLIAKVIQNLA 676
Query: 831 NLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLH 890
N FG KE YM +N F+ ++ M FLDQ++ V D +P + ++A +LA LH
Sbjct: 677 NRAPFGEKEAYMGFMNSFLEEHGPAMQCFLDQVAMV-DVDAAPSGYQGSGDLALQLAVLH 735
>AY032952-1|AAK50336.1| 1065|Homo sapiens nGAP-like protein protein.
Length = 1065
Score = 161 bits (390), Expect = 1e-38
Identities = 129/494 (26%), Positives = 241/494 (48%), Gaps = 34/494 (6%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
VH S+ +++CF++ S + +A E W+E LR P + + R
Sbjct: 36 VHSSILGQDYCFEVTTS-----SGSKCFSCRSAAERDKWMENLRRAVHPNKDNSR----R 86
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHL-RVLLGAAPVARTRPRPSPDP-HWXXXXXXXXM 538
V +L L V + A LPA+ + +L + L ART + D W +
Sbjct: 87 VEHILKLWV--IEAKDLPAK---KKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNL 141
Query: 539 PPDVTSLTITVH---NTGKRGKE---SEVAELTIELANLANGEEIEEWYPLVGMTPIGEW 592
PP T+TVH T K+ K+ S + +++ A++A + +E+WYP+V P G
Sbjct: 142 PP---LRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPVVTPNPKGGK 198
Query: 593 GS---LRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALAD-LCRTDRQPLATSVLNT 648
G +R++ RY ++P E Y + + + AL L ++ +A+++++
Sbjct: 199 GPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHI 258
Query: 649 FAECGRGAELARELTCAEVAREGDHKTL-FRGASLATAVLDEFMRAHCKPFLQAAISETI 707
G+ + +L +EV R GD++ L FR +LAT ++E+++ + +LQ A+ E I
Sbjct: 259 LQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFI 318
Query: 708 QKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQ 767
+ L +S + E++P+K + D + L M + I S P+ ++ + +
Sbjct: 319 KALYESDENCEVDPSKCSAADLPEHQGN-LKMCCELAFCKIINSYCVFPRELKEVFASWR 377
Query: 768 RAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQ 827
+ ++ + + R++S +FLR +CPA++ P + L+Q P R+L ++AK Q
Sbjct: 378 QECSSRGRPD--ISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTARTLTLIAKVTQ 435
Query: 828 NLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELA 887
NLAN +FG+KE YM +N F+ M FL ++SN P+ ++ ++ +EL+
Sbjct: 436 NLANFAKFGSKEEYMSFMNQFLEHEWTNMQRFLLEISN-PETLSNTAGFEGYIDLGRELS 494
Query: 888 TLHHICVAHLTELQ 901
+LH + +++L+
Sbjct: 495 SLHSLLWEAVSQLE 508
>AL365274-4|CAH72158.1| 1065|Homo sapiens DAB2 interacting protein
protein.
Length = 1065
Score = 161 bits (390), Expect = 1e-38
Identities = 129/494 (26%), Positives = 241/494 (48%), Gaps = 34/494 (6%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
VH S+ +++CF++ S + +A E W+E LR P + + R
Sbjct: 36 VHSSILGQDYCFEVTTS-----SGSKCFSCRSAAERDKWMENLRRAVHPNKDNSR----R 86
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHL-RVLLGAAPVARTRPRPSPDP-HWXXXXXXXXM 538
V +L L V + A LPA+ + +L + L ART + D W +
Sbjct: 87 VEHILKLWV--IEAKDLPAK---KKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNL 141
Query: 539 PPDVTSLTITVH---NTGKRGKE---SEVAELTIELANLANGEEIEEWYPLVGMTPIGEW 592
PP T+TVH T K+ K+ S + +++ A++A + +E+WYP+V P G
Sbjct: 142 PP---LRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPVVTPNPKGGK 198
Query: 593 GS---LRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALAD-LCRTDRQPLATSVLNT 648
G +R++ RY ++P E Y + + + AL L ++ +A+++++
Sbjct: 199 GPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHI 258
Query: 649 FAECGRGAELARELTCAEVAREGDHKTL-FRGASLATAVLDEFMRAHCKPFLQAAISETI 707
G+ + +L +EV R GD++ L FR +LAT ++E+++ + +LQ A+ E I
Sbjct: 259 LQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFI 318
Query: 708 QKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQ 767
+ L +S + E++P+K + D + L M + I S P+ ++ + +
Sbjct: 319 KALYESDENCEVDPSKCSAADLPEHQGN-LKMCCELAFCKIINSYCVFPRELKEVFASWR 377
Query: 768 RAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQ 827
+ ++ + + R++S +FLR +CPA++ P + L+Q P R+L ++AK Q
Sbjct: 378 QECSSRGRPD--ISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTARTLTLIAKVTQ 435
Query: 828 NLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELA 887
NLAN +FG+KE YM +N F+ M FL ++SN P+ ++ ++ +EL+
Sbjct: 436 NLANFAKFGSKEEYMSFMNQFLEHEWTNMQRFLLEISN-PETLSNTAGFEGYIDLGRELS 494
Query: 888 TLHHICVAHLTELQ 901
+LH + +++L+
Sbjct: 495 SLHSLLWEAVSQLE 508
>AL365274-1|CAH72155.2| 1132|Homo sapiens DAB2 interacting protein
protein.
Length = 1132
Score = 161 bits (390), Expect = 1e-38
Identities = 129/494 (26%), Positives = 241/494 (48%), Gaps = 34/494 (6%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
VH S+ +++CF++ S + +A E W+E LR P + + R
Sbjct: 132 VHSSILGQDYCFEVTTS-----SGSKCFSCRSAAERDKWMENLRRAVHPNKDNSR----R 182
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHL-RVLLGAAPVARTRPRPSPDP-HWXXXXXXXXM 538
V +L L V + A LPA+ + +L + L ART + D W +
Sbjct: 183 VEHILKLWV--IEAKDLPAK---KKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNL 237
Query: 539 PPDVTSLTITVH---NTGKRGKE---SEVAELTIELANLANGEEIEEWYPLVGMTPIGEW 592
PP T+TVH T K+ K+ S + +++ A++A + +E+WYP+V P G
Sbjct: 238 PP---LRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPVVTPNPKGGK 294
Query: 593 GS---LRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALAD-LCRTDRQPLATSVLNT 648
G +R++ RY ++P E Y + + + AL L ++ +A+++++
Sbjct: 295 GPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHI 354
Query: 649 FAECGRGAELARELTCAEVAREGDHKTL-FRGASLATAVLDEFMRAHCKPFLQAAISETI 707
G+ + +L +EV R GD++ L FR +LAT ++E+++ + +LQ A+ E I
Sbjct: 355 LQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFI 414
Query: 708 QKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQ 767
+ L +S + E++P+K + D + L M + I S P+ ++ + +
Sbjct: 415 KALYESDENCEVDPSKCSAADLPEHQGN-LKMCCELAFCKIINSYCVFPRELKEVFASWR 473
Query: 768 RAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQ 827
+ ++ + + R++S +FLR +CPA++ P + L+Q P R+L ++AK Q
Sbjct: 474 QECSSRGRPD--ISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTARTLTLIAKVTQ 531
Query: 828 NLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELA 887
NLAN +FG+KE YM +N F+ M FL ++SN P+ ++ ++ +EL+
Sbjct: 532 NLANFAKFGSKEEYMSFMNQFLEHEWTNMQRFLLEISN-PETLSNTAGFEGYIDLGRELS 590
Query: 888 TLHHICVAHLTELQ 901
+LH + +++L+
Sbjct: 591 SLHSLLWEAVSQLE 604
>AL357936-1|CAI15112.2| 1132|Homo sapiens DAB2 interacting protein
protein.
Length = 1132
Score = 161 bits (390), Expect = 1e-38
Identities = 129/494 (26%), Positives = 241/494 (48%), Gaps = 34/494 (6%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
VH S+ +++CF++ S + +A E W+E LR P + + R
Sbjct: 132 VHSSILGQDYCFEVTTS-----SGSKCFSCRSAAERDKWMENLRRAVHPNKDNSR----R 182
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHL-RVLLGAAPVARTRPRPSPDP-HWXXXXXXXXM 538
V +L L V + A LPA+ + +L + L ART + D W +
Sbjct: 183 VEHILKLWV--IEAKDLPAK---KKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNL 237
Query: 539 PPDVTSLTITVH---NTGKRGKE---SEVAELTIELANLANGEEIEEWYPLVGMTPIGEW 592
PP T+TVH T K+ K+ S + +++ A++A + +E+WYP+V P G
Sbjct: 238 PP---LRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPVVTPNPKGGK 294
Query: 593 GS---LRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALAD-LCRTDRQPLATSVLNT 648
G +R++ RY ++P E Y + + + AL L ++ +A+++++
Sbjct: 295 GPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHI 354
Query: 649 FAECGRGAELARELTCAEVAREGDHKTL-FRGASLATAVLDEFMRAHCKPFLQAAISETI 707
G+ + +L +EV R GD++ L FR +LAT ++E+++ + +LQ A+ E I
Sbjct: 355 LQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFI 414
Query: 708 QKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQ 767
+ L +S + E++P+K + D + L M + I S P+ ++ + +
Sbjct: 415 KALYESDENCEVDPSKCSAADLPEHQGN-LKMCCELAFCKIINSYCVFPRELKEVFASWR 473
Query: 768 RAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQ 827
+ ++ + + R++S +FLR +CPA++ P + L+Q P R+L ++AK Q
Sbjct: 474 QECSSRGRPD--ISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTARTLTLIAKVTQ 531
Query: 828 NLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELA 887
NLAN +FG+KE YM +N F+ M FL ++SN P+ ++ ++ +EL+
Sbjct: 532 NLANFAKFGSKEEYMSFMNQFLEHEWTNMQRFLLEISN-PETLSNTAGFEGYIDLGRELS 590
Query: 888 TLHHICVAHLTELQ 901
+LH + +++L+
Sbjct: 591 SLHSLLWEAVSQLE 604
>AB051530-1|BAB21834.2| 1036|Homo sapiens KIAA1743 protein protein.
Length = 1036
Score = 161 bits (390), Expect = 1e-38
Identities = 129/494 (26%), Positives = 241/494 (48%), Gaps = 34/494 (6%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
VH S+ +++CF++ S + +A E W+E LR P + + R
Sbjct: 36 VHSSILGQDYCFEVTTS-----SGSKCFSCRSAAERDKWMENLRRAVHPNKDNSR----R 86
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHL-RVLLGAAPVARTRPRPSPDP-HWXXXXXXXXM 538
V +L L V + A LPA+ + +L + L ART + D W +
Sbjct: 87 VEHILKLWV--IEAKDLPAK---KKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNL 141
Query: 539 PPDVTSLTITVH---NTGKRGKE---SEVAELTIELANLANGEEIEEWYPLVGMTPIGEW 592
PP T+TVH T K+ K+ S + +++ A++A + +E+WYP+V P G
Sbjct: 142 PP---LRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPVVTPNPKGGK 198
Query: 593 GS---LRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALAD-LCRTDRQPLATSVLNT 648
G +R++ RY ++P E Y + + + AL L ++ +A+++++
Sbjct: 199 GPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHI 258
Query: 649 FAECGRGAELARELTCAEVAREGDHKTL-FRGASLATAVLDEFMRAHCKPFLQAAISETI 707
G+ + +L +EV R GD++ L FR +LAT ++E+++ + +LQ A+ E I
Sbjct: 259 LQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFI 318
Query: 708 QKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQ 767
+ L +S + E++P+K + D + L M + I S P+ ++ + +
Sbjct: 319 KALYESDENCEVDPSKCSAADLPEHQGN-LKMCCELAFCKIINSYCVFPRELKEVFASWR 377
Query: 768 RAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQ 827
+ ++ + + R++S +FLR +CPA++ P + L+Q P R+L ++AK Q
Sbjct: 378 QECSSRGRPD--ISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTARTLTLIAKVTQ 435
Query: 828 NLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELA 887
NLAN +FG+KE YM +N F+ M FL ++SN P+ ++ ++ +EL+
Sbjct: 436 NLANFAKFGSKEEYMSFMNQFLEHEWTNMQRFLLEISN-PETLSNTAGFEGYIDLGRELS 494
Query: 888 TLHHICVAHLTELQ 901
+LH + +++L+
Sbjct: 495 SLHSLLWEAVSQLE 508
>AK024488-1|BAB15778.1| 674|Homo sapiens FLJ00087 protein protein.
Length = 674
Score = 157 bits (381), Expect = 2e-37
Identities = 124/412 (30%), Positives = 195/412 (47%), Gaps = 15/412 (3%)
Query: 486 WLRVRCLTAHRLPARLAPRPHLR--VLLGAAPVARTRPRPSPDP-HWXXXXXXXXMPPDV 542
WL V A LP A P +R + L A +ART PR P W +PP
Sbjct: 36 WLSVWVHEAKGLPRAAAGAPGVRAELWLDGALLARTAPRAGPGQLFWAERFHFEALPP-A 94
Query: 543 TSLTITVHNTGKRGKESEVAELTIEL--ANLANGEEIEEWYPLVGMTPIGEWGSLRLRIR 600
L++ + G L +E A A +E W+PL+G P G +LR RIR
Sbjct: 95 RRLSLRLRGLGPGSAVLGRVALALEELDAPRAPAAGLERWFPLLG-APAG--AALRARIR 151
Query: 601 YMQELVMPREEYNPLRQLLLEPGIPAVKALAD-LCRTDRQPLATSVLNTFAECGRGAELA 659
+ V+P E Y L + L AL L ++ LA +++ GR L
Sbjct: 152 ARRLRVLPSERYKELAEFLTFHYARLCGALEPALPAQAKEELAAAMVRVLRATGRAQALV 211
Query: 660 RELTCAEVAREGDHKTL-FRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAE 718
+L AE+AR G + L FR +LAT +DE+M+ + +LQ + + +++L S + E
Sbjct: 212 TDLGTAELARCGGREALLFRENTLATKAIDEYMKLVAQDYLQETLGQVVRRLCASTEDCE 271
Query: 719 LNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNER 778
++P+K + + + A L +++ +I S + P + + + A K
Sbjct: 272 VDPSKCPASELPEHQAR-LRNSCEEVFETIIHSYDWFPAELGIVFSSWREAC--KERGSE 328
Query: 779 FVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAK 838
+ R+V +FLRL+CPA++ P + L P P R+L ++AK +QNLAN FG K
Sbjct: 329 VLGPRLVCASLFLRLLCPAILAPSLFGLAPDHPAPGPARTLTLIAKVIQNLANRAPFGEK 388
Query: 839 EPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLH 890
E YM +N F+ ++ M FLDQ++ V D +P + ++A +LA LH
Sbjct: 389 EAYMGFMNSFLEEHGPAMQCFLDQVAMV-DVDAAPSGYQGSGDLALQLAVLH 439
>AF367051-1|AAM00371.1| 967|Homo sapiens DOC-2/DAB2 interactive
protein protein.
Length = 967
Score = 147 bits (356), Expect = 2e-34
Identities = 104/397 (26%), Positives = 199/397 (50%), Gaps = 19/397 (4%)
Query: 517 ARTRPRPSPDP-HWXXXXXXXXMPPDVTSLTITVH---NTGKRGKE---SEVAELTIELA 569
ART + D W +PP T+TVH T K+ K+ S + +++ A
Sbjct: 50 ARTTGKLKTDNVFWGEHFEFHNLPP---LRTVTVHLYRETDKKKKKERNSYLGLVSLPAA 106
Query: 570 NLANGEEIEEWYPLVGMTPIGEWGS---LRLRIRYMQELVMPREEYNPLRQLLLEPGIPA 626
++A + +E+WYP+V P G G +R++ RY ++P E Y + + +
Sbjct: 107 SVAGRQFVEKWYPVVTPNPKGGKGPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGL 166
Query: 627 VKALAD-LCRTDRQPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTL-FRGASLAT 684
AL L ++ +A+++++ G+ + +L +EV R GD++ L FR +LAT
Sbjct: 167 CAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLAT 226
Query: 685 AVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQI 744
++E+++ + +LQ A+ E I+ L +S + E++P+K + D + L M +
Sbjct: 227 KAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCSAADLPEHQGN-LKMCCELA 285
Query: 745 TLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAW 804
S P+ ++ + ++ ++ + + R++S +FLR +CPA++ P +
Sbjct: 286 FCKTINSYCVFPRELKEVFASWRQECSSRGRPD--ISERLISASLFLRFLCPAIMSPSLF 343
Query: 805 TLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLS 864
L+Q P R+L ++AK QNLAN +FG+KE YM +N F+ M FL ++S
Sbjct: 344 NLLQEYPDDRTARTLTLIAKVTQNLANFAKFGSKEEYMSFMNQFLEHEWTNMQRFLLEIS 403
Query: 865 NVPDPGNSPPNSNVNFEIAKELATLHHICVAHLTELQ 901
N P+ ++ ++ +EL++LH + +++L+
Sbjct: 404 N-PETLSNTAGFEGYIDLGRELSSLHSLLWEAVSQLE 439
>AB208935-1|BAD92172.1| 818|Homo sapiens RasGAP-activating-like
protein 1 variant protein.
Length = 818
Score = 141 bits (341), Expect = 1e-32
Identities = 124/418 (29%), Positives = 197/418 (47%), Gaps = 42/418 (10%)
Query: 490 RCLTAHRLPAR-LAPR-------PHLRVLLGAAPVARTRPRPSPDPHWXXXXXXXXMPPD 541
RCL H L AR LAPR P RV G+ + + + + PHW MP
Sbjct: 145 RCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHWDEVLELREMPGA 204
Query: 542 VTSLTITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPI-----GEWGSLR 596
+ L + + + GK + + L + + W+ L+ G G+LR
Sbjct: 205 PSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQ-KPPKGWFRLLPFPRAEEDSGGNLGALR 263
Query: 597 LRIRYMQELVMPREEYNPLRQLLLEPGI-PA-------VKALADLCRTD-RQPLATSVLN 647
+++R +++ V+P + Y PL +LL+E PA + L +L D RQ LAT ++
Sbjct: 264 VKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGDCRQDLATKLVK 323
Query: 648 TFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETI 707
F G LT EVAR D TLFR SLA+ +++FM+ P+L + I
Sbjct: 324 LFLGRGLAGHFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGMPYLHEVLKPVI 383
Query: 708 QKLIDSKQTAELNPTKMD-------SPDDACNNAE-------FLLMILDQITLSIFTSPE 753
++ + K+ EL+P KMD S A + + L L I +I S
Sbjct: 384 SRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLGPIVDAIVGSVG 443
Query: 754 ACPKPVRYLCGCLQRAAVAKWP---NERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRA 810
CP +R L R ++P +++ V+ +SGF+FLR PA++ P+ + L +
Sbjct: 444 RCPPAMRLAFKQLHRRVEERFPQAEHQQDVKYLAISGFLFLRFFAPAILTPKLFDLRDQH 503
Query: 811 PPPHAQRSLLMVAKCLQNLANL-VEFG-AKEPYMEVVNPFILKNKERMVVFLDQLSNV 866
P RSLL++AK +Q++ NL + G KE +M ++PF+L+ R+ FLD+L +V
Sbjct: 504 ADPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVRDFLDRLVDV 561
>BC093724-1|AAH93724.1| 804|Homo sapiens RAS protein activator like
1 (GAP1 like) protein.
Length = 804
Score = 140 bits (340), Expect = 2e-32
Identities = 124/417 (29%), Positives = 195/417 (46%), Gaps = 41/417 (9%)
Query: 490 RCLTAHRLPAR-LAPR-------PHLRVLLGAAPVARTRPRPSPDPHWXXXXXXXXMPPD 541
RCL H L AR LAPR P RV G+ + + + + PHW MP
Sbjct: 133 RCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHWDEVLELREMPGA 192
Query: 542 VTSLTITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPI-----GEWGSLR 596
+ L + + + GK + + L + + W+ L+ G G+LR
Sbjct: 193 PSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQ-KPPKGWFRLLPFPRAEEDSGGNLGALR 251
Query: 597 LRIRYMQELVMPREEYNPLRQLLLEPGI-PA-------VKALADLCRTD-RQPLATSVLN 647
+++R +++ V+P + Y PL +LL+E PA + L +L D RQ LAT ++
Sbjct: 252 VKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGDCRQDLATKLVK 311
Query: 648 TFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETI 707
F G LT EVAR D TLFR SLA+ +++FM+ P+L + I
Sbjct: 312 LFLGRGLAGHFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGMPYLHEVLKPVI 371
Query: 708 QKLIDSKQTAELNPTKMD-------SPDDACNNAE-------FLLMILDQITLSIFTSPE 753
++ + K+ EL+P KMD S A + + L L I +I S
Sbjct: 372 SRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLGPIVDAIVGSVG 431
Query: 754 ACPKPVRYLCGCLQRAAVAKWP--NERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAP 811
CP +R L R ++P + V+ +SGF+FLR PA++ P+ + L +
Sbjct: 432 RCPPAMRLAFKQLHRRVEERFPQAEHQDVKYLAISGFLFLRFFAPAILTPKLFDLRDQHA 491
Query: 812 PPHAQRSLLMVAKCLQNLANL-VEFG-AKEPYMEVVNPFILKNKERMVVFLDQLSNV 866
P RSLL++AK +Q++ NL + G KE +M ++PF+L+ R+ FLD+L +V
Sbjct: 492 DPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVRDFLDRLVDV 548
>BC014420-1|AAH14420.1| 776|Homo sapiens RASAL1 protein protein.
Length = 776
Score = 140 bits (340), Expect = 2e-32
Identities = 124/417 (29%), Positives = 195/417 (46%), Gaps = 41/417 (9%)
Query: 490 RCLTAHRLPAR-LAPR-------PHLRVLLGAAPVARTRPRPSPDPHWXXXXXXXXMPPD 541
RCL H L AR LAPR P RV G+ + + + + PHW MP
Sbjct: 133 RCLRCHVLQARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHWDEVLELREMPGA 192
Query: 542 VTSLTITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPI-----GEWGSLR 596
+ L + + + GK + + L + + W+ L+ G G+LR
Sbjct: 193 PSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQ-KPPKGWFRLLPFPRAEEDSGGNLGALR 251
Query: 597 LRIRYMQELVMPREEYNPLRQLLLEPGI-PA-------VKALADLCRTD-RQPLATSVLN 647
+++R +++ V+P + Y PL +LL+E PA + L +L D RQ LAT ++
Sbjct: 252 VKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGDCRQDLATKLVK 311
Query: 648 TFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETI 707
F G LT EVAR D TLFR SLA+ +++FM+ P+L + I
Sbjct: 312 LFLGRGLAGHFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGMPYLHEVLKPVI 371
Query: 708 QKLIDSKQTAELNPTKMD-------SPDDACNNAE-------FLLMILDQITLSIFTSPE 753
++ + K+ EL+P KMD S A + + L L I +I S
Sbjct: 372 SRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLGPIVDAIVGSVG 431
Query: 754 ACPKPVRYLCGCLQRAAVAKWP--NERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAP 811
CP +R L R ++P + V+ +SGF+FLR PA++ P+ + L +
Sbjct: 432 RCPPAMRLAFKQLHRRVEERFPQAEHQDVKYLAISGFLFLRFFAPAILTPKLFDLRDQHA 491
Query: 812 PPHAQRSLLMVAKCLQNLANL-VEFG-AKEPYMEVVNPFILKNKERMVVFLDQLSNV 866
P RSLL++AK +Q++ NL + G KE +M ++PF+L+ R+ FLD+L +V
Sbjct: 492 DPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVRDFLDRLVDV 548
>AF086713-1|AAD09006.1| 804|Homo sapiens rasGAP-activating-like
protein protein.
Length = 804
Score = 140 bits (339), Expect = 2e-32
Identities = 124/417 (29%), Positives = 195/417 (46%), Gaps = 41/417 (9%)
Query: 490 RCLTAHRLPAR-LAPR-------PHLRVLLGAAPVARTRPRPSPDPHWXXXXXXXXMPPD 541
RCL H L AR LAPR P RV G+ + + + + PHW MP
Sbjct: 133 RCLRCHVLHARDLAPRDISGTSDPFARVFWGSQSLETSTIKKTRFPHWDEVLELREMPGA 192
Query: 542 VTSLTITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPI-----GEWGSLR 596
+ L + + + GK + + L + + W+ L+ G G+LR
Sbjct: 193 PSPLRVELWDWDMVGKNDFLGMVEFSPKTLQQ-KPPKGWFRLLPFPRAEEDSGGNLGALR 251
Query: 597 LRIRYMQELVMPREEYNPLRQLLLEPGI-PA-------VKALADLCRTD-RQPLATSVLN 647
+++R +++ V+P + Y PL +LL+E PA + L +L D RQ LAT ++
Sbjct: 252 VKVRLIEDRVLPSQCYQPLMELLMESVQGPAEEDTASPLALLEELTLGDCRQDLATKLVK 311
Query: 648 TFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETI 707
F G LT EVAR D TLFR SLA+ +++FM+ P+L + I
Sbjct: 312 LFLGRGLAGHFLDYLTRREVARTMDPNTLFRSNSLASKSMEQFMKLVGMPYLHEVLKPVI 371
Query: 708 QKLIDSKQTAELNPTKMD-------SPDDACNNAE-------FLLMILDQITLSIFTSPE 753
++ + K+ EL+P KMD S A + + L L I +I S
Sbjct: 372 SRVFEEKKYMELDPCKMDLGRTRRISFKGALSEEQMRETSLGLLTGYLGPIVDAIVGSVG 431
Query: 754 ACPKPVRYLCGCLQRAAVAKWP--NERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAP 811
CP +R L R ++P + V+ +SGF+FLR PA++ P+ + L +
Sbjct: 432 RCPPAMRLAFKQLHRRVEERFPQAEHQDVKYLAISGFLFLRFFAPAILTPKLFDLRDQHA 491
Query: 812 PPHAQRSLLMVAKCLQNLANL-VEFG-AKEPYMEVVNPFILKNKERMVVFLDQLSNV 866
P RSLL++AK +Q++ NL + G KE +M ++PF+L+ R+ FLD+L +V
Sbjct: 492 DPQTSRSLLLLAKAVQSIGNLGQQLGQGKELWMAPLHPFLLQCVSRVRDFLDRLVDV 548
>X89399-1|CAA61580.1| 834|Homo sapiens Ins P4-binding protein
protein.
Length = 834
Score = 138 bits (333), Expect = 1e-31
Identities = 99/322 (30%), Positives = 155/322 (48%), Gaps = 18/322 (5%)
Query: 561 VAELTIELANLANGEEIEEWYPLV----GMTPI--GEWGSLRLRIRYMQELVMPREEYNP 614
+ EL I L L E WY L G + + GSLRL + Y ++ V + Y+P
Sbjct: 243 LGELRIPLKVLRQSSSYEAWYFLQPRDNGSKSLKPDDLGSLRLNVVYTEDHVFSSDYYSP 302
Query: 615 LRQLLL-----EP-GIPAVKALADLCRTDRQPLATSVLNTFAECGRGAELARELTCAEVA 668
LR LLL EP A L ++CR ++Q A ++ F GR + AEV
Sbjct: 303 LRDLLLKSADVEPVSASAAHILGEVCR-EKQEAAVPLVRLFLHYGRVVPFISAIASAEVK 361
Query: 669 REGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPD 728
R D T+FRG SLA+ +DE M+ +L + I+++ S + E++P K+ +
Sbjct: 362 RTQDPNTIFRGNSLASKCIDETMKLAGMHYLHVTLKPAIEEICQSHKPCEIDPVKLKDGE 421
Query: 729 DACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGF 788
+ NN E L +D++ +I S +CP + + L+ AA ++ ++ VR VS F
Sbjct: 422 NLENNMENLRQYVDRVFHAITESGVSCPTVMCDIFFSLREAAAKRFQDDPDVRYTAVSSF 481
Query: 789 IFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGA---KEPYMEVV 845
IFLR PA++ P + L P R+L +++K +Q L +L + + KE YM
Sbjct: 482 IFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTVQTLGSLSKSKSASFKESYMATF 541
Query: 846 NPFILKNKERMVV--FLDQLSN 865
F + K V FLD +S+
Sbjct: 542 YEFFNEQKYADAVKNFLDLISS 563
>BX537329-1|CAM28365.1| 834|Homo sapiens RAS p21 protein activator
3 protein.
Length = 834
Score = 138 bits (333), Expect = 1e-31
Identities = 99/322 (30%), Positives = 155/322 (48%), Gaps = 18/322 (5%)
Query: 561 VAELTIELANLANGEEIEEWYPLV----GMTPI--GEWGSLRLRIRYMQELVMPREEYNP 614
+ EL I L L E WY L G + + GSLRL + Y ++ V + Y+P
Sbjct: 243 LGELRIPLKVLRQSSSYEAWYFLQPRDNGSKSLKPDDLGSLRLNVVYTEDHVFSSDYYSP 302
Query: 615 LRQLLL-----EP-GIPAVKALADLCRTDRQPLATSVLNTFAECGRGAELARELTCAEVA 668
LR LLL EP A L ++CR ++Q A ++ F GR + AEV
Sbjct: 303 LRDLLLKSADVEPVSASAAHILGEVCR-EKQEAAVPLVRLFLHYGRVVPFISAIASAEVK 361
Query: 669 REGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPD 728
R D T+FRG SLA+ +DE M+ +L + I+++ S + E++P K+ +
Sbjct: 362 RTQDPNTIFRGNSLASKCIDETMKLAGMHYLHVTLKPAIEEICQSHKPCEIDPVKLKDGE 421
Query: 729 DACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGF 788
+ NN E L +D++ +I S +CP + + L+ AA ++ ++ VR VS F
Sbjct: 422 NLENNMENLRQYVDRVFHAITESGVSCPTVMCDIFFSLREAAAKRFQDDPDVRYTAVSSF 481
Query: 789 IFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGA---KEPYMEVV 845
IFLR PA++ P + L P R+L +++K +Q L +L + + KE YM
Sbjct: 482 IFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTVQTLGSLSKSKSASFKESYMATF 541
Query: 846 NPFILKNKERMVV--FLDQLSN 865
F + K V FLD +S+
Sbjct: 542 YEFFNEQKYADAVKNFLDLISS 563
>BC047242-1|AAH47242.1| 834|Homo sapiens RAS p21 protein activator
3 protein.
Length = 834
Score = 138 bits (333), Expect = 1e-31
Identities = 99/322 (30%), Positives = 155/322 (48%), Gaps = 18/322 (5%)
Query: 561 VAELTIELANLANGEEIEEWYPLV----GMTPI--GEWGSLRLRIRYMQELVMPREEYNP 614
+ EL I L L E WY L G + + GSLRL + Y ++ V + Y+P
Sbjct: 243 LGELRIPLKVLRQSSSYEAWYFLQPRDNGSKSLKPDDLGSLRLNVVYTEDHVFSSDYYSP 302
Query: 615 LRQLLL-----EP-GIPAVKALADLCRTDRQPLATSVLNTFAECGRGAELARELTCAEVA 668
LR LLL EP A L ++CR ++Q A ++ F GR + AEV
Sbjct: 303 LRDLLLKSADVEPVSASAAHILGEVCR-EKQEAAVPLVRLFLHYGRVVPFISAIASAEVK 361
Query: 669 REGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPD 728
R D T+FRG SLA+ +DE M+ +L + I+++ S + E++P K+ +
Sbjct: 362 RTQDPNTIFRGNSLASKCIDETMKLAGMHYLHVTLKPAIEEICQSHKPCEIDPVKLKDGE 421
Query: 729 DACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGF 788
+ NN E L +D++ +I S +CP + + L+ AA ++ ++ VR VS F
Sbjct: 422 NLENNMENLRQYVDRVFHAITESGVSCPTVMCDIFFSLREAAAKRFQDDPDVRYTAVSSF 481
Query: 789 IFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGA---KEPYMEVV 845
IFLR PA++ P + L P R+L +++K +Q L +L + + KE YM
Sbjct: 482 IFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTVQTLGSLSKSKSASFKESYMATF 541
Query: 846 NPFILKNKERMVV--FLDQLSN 865
F + K V FLD +S+
Sbjct: 542 YEFFNEQKYADAVKNFLDLISS 563
>BC038456-1|AAH38456.1| 834|Homo sapiens RAS p21 protein activator
3 protein.
Length = 834
Score = 138 bits (333), Expect = 1e-31
Identities = 99/322 (30%), Positives = 155/322 (48%), Gaps = 18/322 (5%)
Query: 561 VAELTIELANLANGEEIEEWYPLV----GMTPI--GEWGSLRLRIRYMQELVMPREEYNP 614
+ EL I L L E WY L G + + GSLRL + Y ++ V + Y+P
Sbjct: 243 LGELRIPLKVLRQSSSYEAWYFLQPRDNGSKSLKPDDLGSLRLNVVYTEDHVFSSDYYSP 302
Query: 615 LRQLLL-----EP-GIPAVKALADLCRTDRQPLATSVLNTFAECGRGAELARELTCAEVA 668
LR LLL EP A L ++CR ++Q A ++ F GR + AEV
Sbjct: 303 LRDLLLKSADVEPVSASAAHILGEVCR-EKQEAAVPLVRLFLHYGRVVPFISAIASAEVK 361
Query: 669 REGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPD 728
R D T+FRG SLA+ +DE M+ +L + I+++ S + E++P K+ +
Sbjct: 362 RTQDPNTIFRGNSLASKCIDETMKLAGMHYLHVTLKPAIEEICQSHKPCEIDPVKLKDGE 421
Query: 729 DACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGF 788
+ NN E L +D++ +I S +CP + + L+ AA ++ ++ VR VS F
Sbjct: 422 NLENNMENLRQYVDRVFHAITESGVSCPTVMCDIFFSLREAAAKRFQDDPDVRYTAVSSF 481
Query: 789 IFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGA---KEPYMEVV 845
IFLR PA++ P + L P R+L +++K +Q L +L + + KE YM
Sbjct: 482 IFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTVQTLGSLSKSKSASFKESYMATF 541
Query: 846 NPFILKNKERMVV--FLDQLSN 865
F + K V FLD +S+
Sbjct: 542 YEFFNEQKYADAVKNFLDLISS 563
>AL161774-1|CAI12864.2| 834|Homo sapiens RAS p21 protein activator
3 protein.
Length = 834
Score = 138 bits (333), Expect = 1e-31
Identities = 99/322 (30%), Positives = 155/322 (48%), Gaps = 18/322 (5%)
Query: 561 VAELTIELANLANGEEIEEWYPLV----GMTPI--GEWGSLRLRIRYMQELVMPREEYNP 614
+ EL I L L E WY L G + + GSLRL + Y ++ V + Y+P
Sbjct: 243 LGELRIPLKVLRQSSSYEAWYFLQPRDNGSKSLKPDDLGSLRLNVVYTEDHVFSSDYYSP 302
Query: 615 LRQLLL-----EP-GIPAVKALADLCRTDRQPLATSVLNTFAECGRGAELARELTCAEVA 668
LR LLL EP A L ++CR ++Q A ++ F GR + AEV
Sbjct: 303 LRDLLLKSADVEPVSASAAHILGEVCR-EKQEAAVPLVRLFLHYGRVVPFISAIASAEVK 361
Query: 669 REGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPD 728
R D T+FRG SLA+ +DE M+ +L + I+++ S + E++P K+ +
Sbjct: 362 RTQDPNTIFRGNSLASKCIDETMKLAGMHYLHVTLKPAIEEICQSHKPCEIDPVKLKDGE 421
Query: 729 DACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGF 788
+ NN E L +D++ +I S +CP + + L+ AA ++ ++ VR VS F
Sbjct: 422 NLENNMENLRQYVDRVFHAITESGVSCPTVMCDIFFSLREAAAKRFQDDPDVRYTAVSSF 481
Query: 789 IFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGA---KEPYMEVV 845
IFLR PA++ P + L P R+L +++K +Q L +L + + KE YM
Sbjct: 482 IFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTVQTLGSLSKSKSASFKESYMATF 541
Query: 846 NPFILKNKERMVV--FLDQLSN 865
F + K V FLD +S+
Sbjct: 542 YEFFNEQKYADAVKNFLDLISS 563
>BX088650-15|CAM26306.1| 1284|Homo sapiens synaptic Ras GTPase
activating protein 1 homolog (rat) protein.
Length = 1284
Score = 136 bits (330), Expect = 3e-31
Identities = 137/535 (25%), Positives = 239/535 (44%), Gaps = 53/535 (9%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
VH S+ +EFCF++ + T F A +A E WIE L+ P + + R
Sbjct: 150 VHSSILGQEFCFEVTTSS----GTKCF-ACRSAAERDKWIENLQRAVKPNKDNSR----R 200
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRP---SPDPHWXXXXXXXX 537
V VL L + + A LP + R + + L ART +P S D +
Sbjct: 201 VDNVLKLWI--IEARELPPK--KRYYCELCLDDMLYARTTSKPRSASGDTVFWGEHFEFN 256
Query: 538 MPPDVTSLTITVHNTG----KRGKESEVAELTIELANLANGEEIEEWYPLV--------- 584
P V +L + ++ K+ K V +T+ +A LA E+WYP+
Sbjct: 257 NLPAVRALRLHLYRDSDKKRKKDKAGYVGLVTVPVATLAGRHFTEQWYPVTLPTGSGGSG 316
Query: 585 GMTPIGEWGS--------------LRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKAL 630
GM G GS +RL+ RY ++P E Y + + L
Sbjct: 317 GMGSGGGGGSGGGSGGKGKGGCPAVRLKARYQTMSILPMELYKEFAEYVTNHYRMLCAVL 376
Query: 631 ADLCRTD-RQPLATSVLNTFAECGRGAELARELTCAEVAR--EGDHKTLFRGASLATAVL 687
++ +A+++++ G+ + ++ +EV R E +H +FR +LAT +
Sbjct: 377 EPALNVKGKEEVASALVHILQSTGKAKDFLSDMAMSEVDRFMEREH-LIFRENTLATKAI 435
Query: 688 DEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLS 747
+E+MR + +L+ AI E I+ L +S++ E++P K + A + A L M +
Sbjct: 436 EEYMRLIGQKYLKDAIGEFIRALYESEENCEVDPIKCTASSLAEHQAN-LRMCCELALCK 494
Query: 748 IFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLV 807
+ S P+ ++ + + + + + R++S +FLR +CPA++ P + L+
Sbjct: 495 VVNSHCVFPRELKEVFASWRLRCAERGRED--IADRLISASLFLRFLCPAIMSPSLFGLM 552
Query: 808 QRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVP 867
Q P R+L ++AK +QNLAN +F +KE ++ +N F+ M FL ++SN+
Sbjct: 553 QEYPDEQTSRTLTLIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGSMQQFLYEISNLD 612
Query: 868 DPGNSPPNSNVNFEIAKELATLHHICVAHLTEL--QGLAKNQPAIRKLVTVTEML 920
NS ++ +EL+TLH + L +L + L K P R L ++ L
Sbjct: 613 TLTNSSSFEGY-IDLGRELSTLHALLWEVLPQLSKEALLKLGPLPRLLNDISTAL 666
>BX088650-14|CAM26305.1| 1343|Homo sapiens synaptic Ras GTPase
activating protein 1 homolog (rat) protein.
Length = 1343
Score = 136 bits (330), Expect = 3e-31
Identities = 137/535 (25%), Positives = 239/535 (44%), Gaps = 53/535 (9%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
VH S+ +EFCF++ + T F A +A E WIE L+ P + + R
Sbjct: 209 VHSSILGQEFCFEVTTSS----GTKCF-ACRSAAERDKWIENLQRAVKPNKDNSR----R 259
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRP---SPDPHWXXXXXXXX 537
V VL L + + A LP + R + + L ART +P S D +
Sbjct: 260 VDNVLKLWI--IEARELPPK--KRYYCELCLDDMLYARTTSKPRSASGDTVFWGEHFEFN 315
Query: 538 MPPDVTSLTITVHNTG----KRGKESEVAELTIELANLANGEEIEEWYPLV--------- 584
P V +L + ++ K+ K V +T+ +A LA E+WYP+
Sbjct: 316 NLPAVRALRLHLYRDSDKKRKKDKAGYVGLVTVPVATLAGRHFTEQWYPVTLPTGSGGSG 375
Query: 585 GMTPIGEWGS--------------LRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKAL 630
GM G GS +RL+ RY ++P E Y + + L
Sbjct: 376 GMGSGGGGGSGGGSGGKGKGGCPAVRLKARYQTMSILPMELYKEFAEYVTNHYRMLCAVL 435
Query: 631 ADLCRTD-RQPLATSVLNTFAECGRGAELARELTCAEVAR--EGDHKTLFRGASLATAVL 687
++ +A+++++ G+ + ++ +EV R E +H +FR +LAT +
Sbjct: 436 EPALNVKGKEEVASALVHILQSTGKAKDFLSDMAMSEVDRFMEREH-LIFRENTLATKAI 494
Query: 688 DEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLS 747
+E+MR + +L+ AI E I+ L +S++ E++P K + A + A L M +
Sbjct: 495 EEYMRLIGQKYLKDAIGEFIRALYESEENCEVDPIKCTASSLAEHQAN-LRMCCELALCK 553
Query: 748 IFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLV 807
+ S P+ ++ + + + + + R++S +FLR +CPA++ P + L+
Sbjct: 554 VVNSHCVFPRELKEVFASWRLRCAERGRED--IADRLISASLFLRFLCPAIMSPSLFGLM 611
Query: 808 QRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVP 867
Q P R+L ++AK +QNLAN +F +KE ++ +N F+ M FL ++SN+
Sbjct: 612 QEYPDEQTSRTLTLIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGSMQQFLYEISNLD 671
Query: 868 DPGNSPPNSNVNFEIAKELATLHHICVAHLTEL--QGLAKNQPAIRKLVTVTEML 920
NS ++ +EL+TLH + L +L + L K P R L ++ L
Sbjct: 672 TLTNSSSFEGY-IDLGRELSTLHALLWEVLPQLSKEALLKLGPLPRLLNDISTAL 725
>BX088650-13|CAM26304.1| 1299|Homo sapiens synaptic Ras GTPase
activating protein 1 homolog (rat) protein.
Length = 1299
Score = 136 bits (330), Expect = 3e-31
Identities = 137/535 (25%), Positives = 239/535 (44%), Gaps = 53/535 (9%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
VH S+ +EFCF++ + T F A +A E WIE L+ P + + R
Sbjct: 209 VHSSILGQEFCFEVTTSS----GTKCF-ACRSAAERDKWIENLQRAVKPNKDNSR----R 259
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRP---SPDPHWXXXXXXXX 537
V VL L + + A LP + R + + L ART +P S D +
Sbjct: 260 VDNVLKLWI--IEARELPPK--KRYYCELCLDDMLYARTTSKPRSASGDTVFWGEHFEFN 315
Query: 538 MPPDVTSLTITVHNTG----KRGKESEVAELTIELANLANGEEIEEWYPLV--------- 584
P V +L + ++ K+ K V +T+ +A LA E+WYP+
Sbjct: 316 NLPAVRALRLHLYRDSDKKRKKDKAGYVGLVTVPVATLAGRHFTEQWYPVTLPTGSGGSG 375
Query: 585 GMTPIGEWGS--------------LRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKAL 630
GM G GS +RL+ RY ++P E Y + + L
Sbjct: 376 GMGSGGGGGSGGGSGGKGKGGCPAVRLKARYQTMSILPMELYKEFAEYVTNHYRMLCAVL 435
Query: 631 ADLCRTD-RQPLATSVLNTFAECGRGAELARELTCAEVAR--EGDHKTLFRGASLATAVL 687
++ +A+++++ G+ + ++ +EV R E +H +FR +LAT +
Sbjct: 436 EPALNVKGKEEVASALVHILQSTGKAKDFLSDMAMSEVDRFMEREH-LIFRENTLATKAI 494
Query: 688 DEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLS 747
+E+MR + +L+ AI E I+ L +S++ E++P K + A + A L M +
Sbjct: 495 EEYMRLIGQKYLKDAIGEFIRALYESEENCEVDPIKCTASSLAEHQAN-LRMCCELALCK 553
Query: 748 IFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLV 807
+ S P+ ++ + + + + + R++S +FLR +CPA++ P + L+
Sbjct: 554 VVNSHCVFPRELKEVFASWRLRCAERGRED--IADRLISASLFLRFLCPAIMSPSLFGLM 611
Query: 808 QRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVP 867
Q P R+L ++AK +QNLAN +F +KE ++ +N F+ M FL ++SN+
Sbjct: 612 QEYPDEQTSRTLTLIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGSMQQFLYEISNLD 671
Query: 868 DPGNSPPNSNVNFEIAKELATLHHICVAHLTEL--QGLAKNQPAIRKLVTVTEML 920
NS ++ +EL+TLH + L +L + L K P R L ++ L
Sbjct: 672 TLTNSSSFEGY-IDLGRELSTLHALLWEVLPQLSKEALLKLGPLPRLLNDISTAL 725
>AL662799-15|CAM25572.1| 1284|Homo sapiens synaptic Ras GTPase
activating protein 1 homolog (rat) protein.
Length = 1284
Score = 136 bits (330), Expect = 3e-31
Identities = 137/535 (25%), Positives = 239/535 (44%), Gaps = 53/535 (9%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
VH S+ +EFCF++ + T F A +A E WIE L+ P + + R
Sbjct: 150 VHSSILGQEFCFEVTTSS----GTKCF-ACRSAAERDKWIENLQRAVKPNKDNSR----R 200
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRP---SPDPHWXXXXXXXX 537
V VL L + + A LP + R + + L ART +P S D +
Sbjct: 201 VDNVLKLWI--IEARELPPK--KRYYCELCLDDMLYARTTSKPRSASGDTVFWGEHFEFN 256
Query: 538 MPPDVTSLTITVHNTG----KRGKESEVAELTIELANLANGEEIEEWYPLV--------- 584
P V +L + ++ K+ K V +T+ +A LA E+WYP+
Sbjct: 257 NLPAVRALRLHLYRDSDKKRKKDKAGYVGLVTVPVATLAGRHFTEQWYPVTLPTGSGGSG 316
Query: 585 GMTPIGEWGS--------------LRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKAL 630
GM G GS +RL+ RY ++P E Y + + L
Sbjct: 317 GMGSGGGGGSGGGSGGKGKGGCPAVRLKARYQTMSILPMELYKEFAEYVTNHYRMLCAVL 376
Query: 631 ADLCRTD-RQPLATSVLNTFAECGRGAELARELTCAEVAR--EGDHKTLFRGASLATAVL 687
++ +A+++++ G+ + ++ +EV R E +H +FR +LAT +
Sbjct: 377 EPALNVKGKEEVASALVHILQSTGKAKDFLSDMAMSEVDRFMEREH-LIFRENTLATKAI 435
Query: 688 DEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLS 747
+E+MR + +L+ AI E I+ L +S++ E++P K + A + A L M +
Sbjct: 436 EEYMRLIGQKYLKDAIGEFIRALYESEENCEVDPIKCTASSLAEHQAN-LRMCCELALCK 494
Query: 748 IFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLV 807
+ S P+ ++ + + + + + R++S +FLR +CPA++ P + L+
Sbjct: 495 VVNSHCVFPRELKEVFASWRLRCAERGRED--IADRLISASLFLRFLCPAIMSPSLFGLM 552
Query: 808 QRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVP 867
Q P R+L ++AK +QNLAN +F +KE ++ +N F+ M FL ++SN+
Sbjct: 553 QEYPDEQTSRTLTLIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGSMQQFLYEISNLD 612
Query: 868 DPGNSPPNSNVNFEIAKELATLHHICVAHLTEL--QGLAKNQPAIRKLVTVTEML 920
NS ++ +EL+TLH + L +L + L K P R L ++ L
Sbjct: 613 TLTNSSSFEGY-IDLGRELSTLHALLWEVLPQLSKEALLKLGPLPRLLNDISTAL 666
>AL662799-14|CAI18276.2| 1343|Homo sapiens synaptic Ras GTPase
activating protein 1 homolog (rat) protein.
Length = 1343
Score = 136 bits (330), Expect = 3e-31
Identities = 137/535 (25%), Positives = 239/535 (44%), Gaps = 53/535 (9%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
VH S+ +EFCF++ + T F A +A E WIE L+ P + + R
Sbjct: 209 VHSSILGQEFCFEVTTSS----GTKCF-ACRSAAERDKWIENLQRAVKPNKDNSR----R 259
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRP---SPDPHWXXXXXXXX 537
V VL L + + A LP + R + + L ART +P S D +
Sbjct: 260 VDNVLKLWI--IEARELPPK--KRYYCELCLDDMLYARTTSKPRSASGDTVFWGEHFEFN 315
Query: 538 MPPDVTSLTITVHNTG----KRGKESEVAELTIELANLANGEEIEEWYPLV--------- 584
P V +L + ++ K+ K V +T+ +A LA E+WYP+
Sbjct: 316 NLPAVRALRLHLYRDSDKKRKKDKAGYVGLVTVPVATLAGRHFTEQWYPVTLPTGSGGSG 375
Query: 585 GMTPIGEWGS--------------LRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKAL 630
GM G GS +RL+ RY ++P E Y + + L
Sbjct: 376 GMGSGGGGGSGGGSGGKGKGGCPAVRLKARYQTMSILPMELYKEFAEYVTNHYRMLCAVL 435
Query: 631 ADLCRTD-RQPLATSVLNTFAECGRGAELARELTCAEVAR--EGDHKTLFRGASLATAVL 687
++ +A+++++ G+ + ++ +EV R E +H +FR +LAT +
Sbjct: 436 EPALNVKGKEEVASALVHILQSTGKAKDFLSDMAMSEVDRFMEREH-LIFRENTLATKAI 494
Query: 688 DEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLS 747
+E+MR + +L+ AI E I+ L +S++ E++P K + A + A L M +
Sbjct: 495 EEYMRLIGQKYLKDAIGEFIRALYESEENCEVDPIKCTASSLAEHQAN-LRMCCELALCK 553
Query: 748 IFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLV 807
+ S P+ ++ + + + + + R++S +FLR +CPA++ P + L+
Sbjct: 554 VVNSHCVFPRELKEVFASWRLRCAERGRED--IADRLISASLFLRFLCPAIMSPSLFGLM 611
Query: 808 QRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVP 867
Q P R+L ++AK +QNLAN +F +KE ++ +N F+ M FL ++SN+
Sbjct: 612 QEYPDEQTSRTLTLIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGSMQQFLYEISNLD 671
Query: 868 DPGNSPPNSNVNFEIAKELATLHHICVAHLTEL--QGLAKNQPAIRKLVTVTEML 920
NS ++ +EL+TLH + L +L + L K P R L ++ L
Sbjct: 672 TLTNSSSFEGY-IDLGRELSTLHALLWEVLPQLSKEALLKLGPLPRLLNDISTAL 725
>AB067525-1|BAB67831.2| 1376|Homo sapiens KIAA1938 protein protein.
Length = 1376
Score = 136 bits (330), Expect = 3e-31
Identities = 137/535 (25%), Positives = 239/535 (44%), Gaps = 53/535 (9%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
VH S+ +EFCF++ + T F A +A E WIE L+ P + + R
Sbjct: 242 VHSSILGQEFCFEVTTSS----GTKCF-ACRSAAERDKWIENLQRAVKPNKDNSR----R 292
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRP---SPDPHWXXXXXXXX 537
V VL L + + A LP + R + + L ART +P S D +
Sbjct: 293 VDNVLKLWI--IEARELPPK--KRYYCELCLDDMLYARTTSKPRSASGDTVFWGEHFEFN 348
Query: 538 MPPDVTSLTITVHNTG----KRGKESEVAELTIELANLANGEEIEEWYPLV--------- 584
P V +L + ++ K+ K V +T+ +A LA E+WYP+
Sbjct: 349 NLPAVRALRLHLYRDSDKKRKKDKAGYVGLVTVPVATLAGRHFTEQWYPVTLPTGSGGSG 408
Query: 585 GMTPIGEWGS--------------LRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKAL 630
GM G GS +RL+ RY ++P E Y + + L
Sbjct: 409 GMGSGGGGGSGGGSGGKGKGGCPAVRLKARYQTMSILPMELYKEFAEYVTNHYRMLCAVL 468
Query: 631 ADLCRTD-RQPLATSVLNTFAECGRGAELARELTCAEVAR--EGDHKTLFRGASLATAVL 687
++ +A+++++ G+ + ++ +EV R E +H +FR +LAT +
Sbjct: 469 EPALNVKGKEEVASALVHILQSTGKAKDFLSDMAMSEVDRFMEREH-LIFRENTLATKAI 527
Query: 688 DEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLS 747
+E+MR + +L+ AI E I+ L +S++ E++P K + A + A L M +
Sbjct: 528 EEYMRLIGQKYLKDAIGEFIRALYESEENCEVDPIKCTASSLAEHQAN-LRMCCELALCK 586
Query: 748 IFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLV 807
+ S P+ ++ + + + + + R++S +FLR +CPA++ P + L+
Sbjct: 587 VVNSHCVFPRELKEVFASWRLRCAERGRED--IADRLISASLFLRFLCPAIMSPSLFGLM 644
Query: 808 QRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVP 867
Q P R+L ++AK +QNLAN +F +KE ++ +N F+ M FL ++SN+
Sbjct: 645 QEYPDEQTSRTLTLIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGSMQQFLYEISNLD 704
Query: 868 DPGNSPPNSNVNFEIAKELATLHHICVAHLTEL--QGLAKNQPAIRKLVTVTEML 920
NS ++ +EL+TLH + L +L + L K P R L ++ L
Sbjct: 705 TLTNSSSFEGY-IDLGRELSTLHALLWEVLPQLSKEALLKLGPLPRLLNDISTAL 758
>D82880-1|BAA11621.1| 853|Homo sapiens human ras GTPase-activating
protein, Gap1m protein.
Length = 853
Score = 123 bits (297), Expect = 3e-27
Identities = 81/299 (27%), Positives = 145/299 (48%), Gaps = 13/299 (4%)
Query: 545 LTITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLVGM------TPIGEWGSLRLR 598
+ I + N G ++ + E+ + + L + WY L + + GSLRL
Sbjct: 253 IRIDLWNNGNLVQDVFLGEIKVPVNVLRTDSSHQAWYLLQPRDNGNKSSKTDDLGSLRLN 312
Query: 599 IRYMQELVMPREEYNPLRQLLLE-PGIPAVKA-----LADLCRTDRQPLATSVLNTFAEC 652
I Y ++ V+P E Y PL+ LLL+ P + + A L+++CR D+ ++
Sbjct: 313 ICYTEDYVLPSEYYGPLKTLLLKSPDVQPISASAAYILSEICR-DKNDAVLPLVRLLLHH 371
Query: 653 GRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLID 712
+ A + ++ D T+FRG SLAT LDE M+ +L+ + + ++ D
Sbjct: 372 DKLVPFATAVAELDLKDTQDANTIFRGNSLATRCLDEMMKIVGGHYLKVTLKPILDEICD 431
Query: 713 SKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVA 772
S ++ E++P K+ D+ NN E L +D++ +I S +CP + + L++ A
Sbjct: 432 SSKSCEIDPIKLKEGDNVENNKENLRYYVDKLFNTIVKSSMSCPTVMCDIFYSLRQMATQ 491
Query: 773 KWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLAN 831
++PN+ V+ VS F+FLR A+V P + L P R+L +++K +Q L +
Sbjct: 492 RFPNDPHVQYSAVSSFVFLRFFAVAVVSPHTFHLRPHHPDAQTIRTLTLISKTIQTLGS 550
>D78155-1|BAA11230.1| 850|Homo sapiens rasGTPase activating protein
protein.
Length = 850
Score = 123 bits (297), Expect = 3e-27
Identities = 81/299 (27%), Positives = 145/299 (48%), Gaps = 13/299 (4%)
Query: 545 LTITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLVGM------TPIGEWGSLRLR 598
+ I + N G ++ + E+ + + L + WY L + + GSLRL
Sbjct: 253 IRIDLWNNGNLVQDVFLGEIKVPVNVLRTDSSHQAWYLLQPRDNGNKSSKTDDLGSLRLN 312
Query: 599 IRYMQELVMPREEYNPLRQLLLE-PGIPAVKA-----LADLCRTDRQPLATSVLNTFAEC 652
I Y ++ V+P E Y PL+ LLL+ P + + A L+++CR D+ ++
Sbjct: 313 ICYTEDYVLPSEYYGPLKTLLLKSPDVQPISASAAYILSEICR-DKNDAVLPLVRLLLHH 371
Query: 653 GRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLID 712
+ A + ++ D T+FRG SLAT LDE M+ +L+ + + ++ D
Sbjct: 372 DKLVPFATAVAELDLKDTQDANTIFRGNSLATRCLDEMMKIVGGHYLKVTLKPILDEICD 431
Query: 713 SKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVA 772
S ++ E++P K+ D+ NN E L +D++ +I S +CP + + L++ A
Sbjct: 432 SSKSCEIDPIKLKEGDNVENNKENLRYYVDKLFNTIVKSSMSCPTVMCDIFYSLRQMATQ 491
Query: 773 KWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLAN 831
++PN+ V+ VS F+FLR A+V P + L P R+L +++K +Q L +
Sbjct: 492 RFPNDPHVQYSAVSSFVFLRFFAVAVVSPHTFHLRPHHPDAQTIRTLTLISKTIQTLGS 550
>AF115573-1|AAD09821.1| 849|Homo sapiens GTPase-activating protein
GAP1m protein.
Length = 849
Score = 123 bits (297), Expect = 3e-27
Identities = 81/299 (27%), Positives = 145/299 (48%), Gaps = 13/299 (4%)
Query: 545 LTITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLVGM------TPIGEWGSLRLR 598
+ I + N G ++ + E+ + + L + WY L + + GSLRL
Sbjct: 253 IRIDLWNNGNLVQDVFLGEIKVPVNVLRTDSSHQAWYLLQPRDNGNKSSKTDDLGSLRLN 312
Query: 599 IRYMQELVMPREEYNPLRQLLLE-PGIPAVKA-----LADLCRTDRQPLATSVLNTFAEC 652
I Y ++ V+P E Y PL+ LLL+ P + + A L+++CR D+ ++
Sbjct: 313 ICYTEDYVLPSEYYGPLKTLLLKSPDVQPISASAAYILSEICR-DKNDAVLPLVRLLLHH 371
Query: 653 GRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLID 712
+ A + ++ D T+FRG SLAT LDE M+ +L+ + + ++ D
Sbjct: 372 DKLVPFATAVAELDLKDTQDANTIFRGNSLATRCLDEMMKIVGGHYLKVTLKPILDEICD 431
Query: 713 SKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVA 772
S ++ E++P K+ D+ NN E L +D++ +I S +CP + + L++ A
Sbjct: 432 SSKSCEIDPIKLKEGDNVENNKENLRYYVDKLFNTIVKSSMSCPTVMCDIFYSLRQMATQ 491
Query: 773 KWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLAN 831
++PN+ V+ VS F+FLR A+V P + L P R+L +++K +Q L +
Sbjct: 492 RFPNDPHVQYSAVSSFVFLRFFAVAVVSPHTFHLRPHHPDAQTIRTLTLISKTIQTLGS 550
>AL713634-1|CAD28452.1| 902|Homo sapiens hypothetical protein
protein.
Length = 902
Score = 118 bits (284), Expect = 1e-25
Identities = 85/332 (25%), Positives = 162/332 (48%), Gaps = 10/332 (3%)
Query: 594 SLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRTD-RQPLATSVLNTFAEC 652
++RL+ RY ++P E Y + + L ++ +A+++++
Sbjct: 16 AVRLKARYQTMSILPMELYKEFAEYVTNHYRMLCAVLEPALNVKGKEEVASALVHILQST 75
Query: 653 GRGAELARELTCAEVAR--EGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKL 710
G+ + ++ +EV R E +H +FR +LAT ++E+MR + +L+ AI E I+ L
Sbjct: 76 GKAKDFLSDMAMSEVDRFMEREH-LIFRENTLATKAIEEYMRLIGQKYLKDAIGEFIRAL 134
Query: 711 IDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAA 770
+S++ E++P K + A + A L M + + S P+ ++ + +
Sbjct: 135 YESEENCEVDPIKCTASSLAEHQAN-LRMCCELALCKVVNSHCVFPRELKEVFASWRLRC 193
Query: 771 VAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLA 830
+ + + R++S +FLR +CPA++ P + L+Q P R+L ++AK +QNLA
Sbjct: 194 AERGRED--IADRLISASLFLRFLCPAIMSPSLFGLMQEYPDEQTSRTLTLIAKVIQNLA 251
Query: 831 NLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLH 890
N +F +KE ++ +N F+ M FL ++SN+ NS ++ +EL+TLH
Sbjct: 252 NFSKFTSKEDFLGFMNEFLELEWGSMQQFLYEISNLDTLTNSSSFEGY-IDLGRELSTLH 310
Query: 891 HICVAHLTEL--QGLAKNQPAIRKLVTVTEML 920
+ L +L + L K P R L ++ L
Sbjct: 311 ALLWEVLPQLSKEALLKLGPLPRLLNDISTAL 342
>AC105052-1|AAP22345.1| 724|Homo sapiens unknown protein.
Length = 724
Score = 105 bits (253), Expect = 6e-22
Identities = 83/306 (27%), Positives = 144/306 (47%), Gaps = 28/306 (9%)
Query: 590 GEWGSLRLRIRYMQELVMPREEYNPLRQLLLE--------PGIPAVKALADLCRTD-RQP 640
G GSL+L +R E V+P Y PL LL PG + + + T+ RQ
Sbjct: 270 GNLGSLQLEVRLRDETVLPSSYYQPLVHLLCHEVKLGMQGPG-QLIPLIEETTSTECRQD 328
Query: 641 LATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQ 700
+AT++L F G + L E++R + TLFR SLA+ ++ F++ +L
Sbjct: 329 VATNLLKLFLGQGLAKDFLDLLFQLELSRTSETNTLFRSNSLASKSMESFLKVAGMQYLH 388
Query: 701 AAISETIQKLIDSKQTAELNPTKMDSPDDACN--------------NAEFLLMILDQITL 746
+ I K+ + K+ EL+P+K++ D C+ +A+ L L +
Sbjct: 389 GVLGPIINKVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLS 448
Query: 747 SIFTSPEACPKPVRYLCGCLQRAAVAKWPNERF--VRTRVVSGFIFLRLICPALVEPRAW 804
++ S ACP VR L R ++P + V V+ F+ LR PA++ P+ +
Sbjct: 449 ALSRSVRACPAVVRATFRQLFRRVRERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPKLF 508
Query: 805 TLVQRAPPPHAQRSLLMVAKCLQNLANL--VEFGAKEPYMEVVNPFILKNKERMVVFLDQ 862
L +R R+LL++AK +QN+ N+ AKE +ME + P + + ++ F+ +
Sbjct: 509 HLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVRQGVAQLKDFITK 568
Query: 863 LSNVPD 868
L ++ +
Sbjct: 569 LVDIEE 574
>AB011110-1|BAA25464.2| 816|Homo sapiens KIAA0538 protein protein.
Length = 816
Score = 105 bits (253), Expect = 6e-22
Identities = 83/306 (27%), Positives = 144/306 (47%), Gaps = 28/306 (9%)
Query: 590 GEWGSLRLRIRYMQELVMPREEYNPLRQLLLE--------PGIPAVKALADLCRTD-RQP 640
G GSL+L +R E V+P Y PL LL PG + + + T+ RQ
Sbjct: 260 GNLGSLQLEVRLRDETVLPSSYYQPLVHLLCHEVKLGMQGPG-QLIPLIEETTSTECRQD 318
Query: 641 LATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQ 700
+AT++L F G + L E++R + TLFR SLA+ ++ F++ +L
Sbjct: 319 VATNLLKLFLGQGLAKDFLDLLFQLELSRTSETNTLFRSNSLASKSMESFLKVAGMQYLH 378
Query: 701 AAISETIQKLIDSKQTAELNPTKMDSPDDACN--------------NAEFLLMILDQITL 746
+ I K+ + K+ EL+P+K++ D C+ +A+ L L +
Sbjct: 379 GVLGPIINKVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLS 438
Query: 747 SIFTSPEACPKPVRYLCGCLQRAAVAKWPNERF--VRTRVVSGFIFLRLICPALVEPRAW 804
++ S ACP VR L R ++P + V V+ F+ LR PA++ P+ +
Sbjct: 439 ALSRSVRACPAVVRATFRQLFRRVRERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPKLF 498
Query: 805 TLVQRAPPPHAQRSLLMVAKCLQNLANL--VEFGAKEPYMEVVNPFILKNKERMVVFLDQ 862
L +R R+LL++AK +QN+ N+ AKE +ME + P + + ++ F+ +
Sbjct: 499 HLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVRQGVAQLKDFITK 558
Query: 863 LSNVPD 868
L ++ +
Sbjct: 559 LVDIEE 564
>BC113663-1|AAI13664.1| 803|Homo sapiens RAS p21 protein activator
4 protein.
Length = 803
Score = 105 bits (252), Expect = 7e-22
Identities = 83/306 (27%), Positives = 144/306 (47%), Gaps = 28/306 (9%)
Query: 590 GEWGSLRLRIRYMQELVMPREEYNPLRQLLLE--------PGIPAVKALADLCRTD-RQP 640
G GSL+L +R E V+P Y PL LL PG + + + T+ RQ
Sbjct: 247 GNLGSLQLEVRLRDETVLPSSYYQPLVHLLCHEVKLGMQGPG-QLIPLIEETTSTECRQD 305
Query: 641 LATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQ 700
+AT++L F G + L E++R + TLFR SLA+ ++ F++ +L
Sbjct: 306 VATNLLKLFLGQGLAKDFLDLLFQLELSRTSETNTLFRSNSLASKSVESFLKVAGMQYLH 365
Query: 701 AAISETIQKLIDSKQTAELNPTKMDSPDDACN--------------NAEFLLMILDQITL 746
+ I K+ + K+ EL+P+K++ D C+ +A+ L L +
Sbjct: 366 GVLGPIINKVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLS 425
Query: 747 SIFTSPEACPKPVRYLCGCLQRAAVAKWPNERF--VRTRVVSGFIFLRLICPALVEPRAW 804
++ S ACP VR L R ++P + V V+ F+ LR PA++ P+ +
Sbjct: 426 ALSRSVRACPAVVRATFRQLFRRVRERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPKLF 485
Query: 805 TLVQRAPPPHAQRSLLMVAKCLQNLANL--VEFGAKEPYMEVVNPFILKNKERMVVFLDQ 862
L +R R+LL++AK +QN+ N+ AKE +ME + P + + ++ F+ +
Sbjct: 486 HLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVRQGVAQLKDFITK 545
Query: 863 LSNVPD 868
L ++ +
Sbjct: 546 LVDIEE 551
>BC110873-1|AAI10874.1| 803|Homo sapiens RAS p21 protein activator
4 protein.
Length = 803
Score = 105 bits (252), Expect = 7e-22
Identities = 83/306 (27%), Positives = 144/306 (47%), Gaps = 28/306 (9%)
Query: 590 GEWGSLRLRIRYMQELVMPREEYNPLRQLLLE--------PGIPAVKALADLCRTD-RQP 640
G GSL+L +R E V+P Y PL LL PG + + + T+ RQ
Sbjct: 247 GNLGSLQLEVRLRDETVLPSSYYQPLVHLLCHEVKLGMQGPG-QLIPLIEETTSTECRQD 305
Query: 641 LATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQ 700
+AT++L F G + L E++R + TLFR SLA+ ++ F++ +L
Sbjct: 306 VATNLLKLFLGQGLAKDFLDLLFQLELSRTSETNTLFRSNSLASKSVESFLKVAGMQYLH 365
Query: 701 AAISETIQKLIDSKQTAELNPTKMDSPDDACN--------------NAEFLLMILDQITL 746
+ I K+ + K+ EL+P+K++ D C+ +A+ L L +
Sbjct: 366 GVLGPIINKVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLS 425
Query: 747 SIFTSPEACPKPVRYLCGCLQRAAVAKWPNERF--VRTRVVSGFIFLRLICPALVEPRAW 804
++ S ACP VR L R ++P + V V+ F+ LR PA++ P+ +
Sbjct: 426 ALSRSVRACPAVVRATFRQLFRRVRERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPKLF 485
Query: 805 TLVQRAPPPHAQRSLLMVAKCLQNLANL--VEFGAKEPYMEVVNPFILKNKERMVVFLDQ 862
L +R R+LL++AK +QN+ N+ AKE +ME + P + + ++ F+ +
Sbjct: 486 HLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVRQGVAQLKDFITK 545
Query: 863 LSNVPD 868
L ++ +
Sbjct: 546 LVDIEE 551
>AY029206-1|AAK31582.1| 803|Homo sapiens calcium-promoted Ras
inactivator protein.
Length = 803
Score = 105 bits (252), Expect = 7e-22
Identities = 83/306 (27%), Positives = 144/306 (47%), Gaps = 28/306 (9%)
Query: 590 GEWGSLRLRIRYMQELVMPREEYNPLRQLLLE--------PGIPAVKALADLCRTD-RQP 640
G GSL+L +R E V+P Y PL LL PG + + + T+ RQ
Sbjct: 247 GNLGSLQLEVRLRDETVLPSSYYQPLVHLLCHEVKLGMQGPG-QLIPLIEETTSTECRQD 305
Query: 641 LATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQ 700
+AT++L F G + L E++R + TLFR SLA+ ++ F++ +L
Sbjct: 306 VATNLLKLFLGQGLAKDFLDLLFQLELSRTSETNTLFRSNSLASKSVESFLKVAGMQYLH 365
Query: 701 AAISETIQKLIDSKQTAELNPTKMDSPDDACN--------------NAEFLLMILDQITL 746
+ I K+ + K+ EL+P+K++ D C+ +A+ L L +
Sbjct: 366 GVLGPIINKVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLS 425
Query: 747 SIFTSPEACPKPVRYLCGCLQRAAVAKWPNERF--VRTRVVSGFIFLRLICPALVEPRAW 804
++ S ACP VR L R ++P + V V+ F+ LR PA++ P+ +
Sbjct: 426 ALSRSVRACPAVVRATFRQLFRRVRERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPKLF 485
Query: 805 TLVQRAPPPHAQRSLLMVAKCLQNLANL--VEFGAKEPYMEVVNPFILKNKERMVVFLDQ 862
L +R R+LL++AK +QN+ N+ AKE +ME + P + + ++ F+ +
Sbjct: 486 HLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVRQGVAQLKDFITK 545
Query: 863 LSNVPD 868
L ++ +
Sbjct: 546 LVDIEE 551
>U17690-2|AAB48379.1| 840|Homo sapiens neurofibromatosis 1 protein.
Length = 840
Score = 93.9 bits (223), Expect = 2e-18
Identities = 72/275 (26%), Positives = 129/275 (46%), Gaps = 12/275 (4%)
Query: 624 IPAVKALADLCRTDR-QPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASL 682
+P ALA++ + LA ++ F +L + EV +TLFRG SL
Sbjct: 471 LPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSL 530
Query: 683 ATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQ----TAELNPTKMDSPDDACNNAEFLL 738
A+ ++ + + +LQ + ++ +I S + E++PT+++ + N LL
Sbjct: 531 ASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLEPSESLEENQRNLL 590
Query: 739 MILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPAL 798
+ ++ +I +S P +R +C CL + ++P V +FLR I PA+
Sbjct: 591 QMTEKFFHAIISSSSEFPPQLRSVCHCLYQVVSQRFPQNSI---GAVGSAMFLRFINPAI 647
Query: 799 VEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKE-RMV 857
V P ++ + PPP +R L +++K LQ++AN V F KE +M N F+ N +
Sbjct: 648 VSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLF-TKEEHMRPFNDFVKSNFDAARR 706
Query: 858 VFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHI 892
FLD S+ P + N +++F + LH +
Sbjct: 707 FFLDIASDCPT--SDAVNHSLSFISDGNVLALHRL 739
>M82814-1|AAA59924.1| 2818|Homo sapiens GAP-related protein protein.
Length = 2818
Score = 93.9 bits (223), Expect = 2e-18
Identities = 72/275 (26%), Positives = 129/275 (46%), Gaps = 12/275 (4%)
Query: 624 IPAVKALADLCRTDR-QPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASL 682
+P ALA++ + LA ++ F +L + EV +TLFRG SL
Sbjct: 1221 LPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSL 1280
Query: 683 ATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQ----TAELNPTKMDSPDDACNNAEFLL 738
A+ ++ + + +LQ + ++ +I S + E++PT+++ + N LL
Sbjct: 1281 ASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLEPSESLEENQRNLL 1340
Query: 739 MILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPAL 798
+ ++ +I +S P +R +C CL + ++P V +FLR I PA+
Sbjct: 1341 QMTEKFFHAIISSSSEFPPQLRSVCHCLYQVVSQRFPQNSI---GAVGSAMFLRFINPAI 1397
Query: 799 VEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKE-RMV 857
V P ++ + PPP +R L +++K LQ++AN V F KE +M N F+ N +
Sbjct: 1398 VSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLF-TKEEHMRPFNDFVKSNFDAARR 1456
Query: 858 VFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHI 892
FLD S+ P + N +++F + LH +
Sbjct: 1457 FFLDIASDCPT--SDAVNHSLSFISDGNVLALHRL 1489
>M61213-1|AAA59923.1| 482|Homo sapiens neurofibromatosis protein
type 1 protein.
Length = 482
Score = 93.9 bits (223), Expect = 2e-18
Identities = 72/275 (26%), Positives = 129/275 (46%), Gaps = 12/275 (4%)
Query: 624 IPAVKALADLCRTDR-QPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASL 682
+P ALA++ + LA ++ F +L + EV +TLFRG SL
Sbjct: 126 LPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSL 185
Query: 683 ATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQ----TAELNPTKMDSPDDACNNAEFLL 738
A+ ++ + + +LQ + ++ +I S + E++PT+++ + N LL
Sbjct: 186 ASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLEPSESLEENQRNLL 245
Query: 739 MILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPAL 798
+ ++ +I +S P +R +C CL + ++P V +FLR I PA+
Sbjct: 246 QMTEKFFHAIISSSSEFPPQLRSVCHCLYQVVSQRFPQNSI---GAVGSAMFLRFINPAI 302
Query: 799 VEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKE-RMV 857
V P ++ + PPP +R L +++K LQ++AN V F KE +M N F+ N +
Sbjct: 303 VSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLF-TKEEHMRPFNDFVKSNFDAARR 361
Query: 858 VFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHI 892
FLD S+ P + N +++F + LH +
Sbjct: 362 FFLDIASDCPT--SDAVNHSLSFISDGNVLALHRL 394
>M60915-2|AAA59922.1| 378|Homo sapiens neurofibromatosis protein
type 1 protein.
Length = 378
Score = 93.9 bits (223), Expect = 2e-18
Identities = 72/275 (26%), Positives = 129/275 (46%), Gaps = 12/275 (4%)
Query: 624 IPAVKALADLCRTDR-QPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASL 682
+P ALA++ + LA ++ F +L + EV +TLFRG SL
Sbjct: 54 LPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSL 113
Query: 683 ATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQ----TAELNPTKMDSPDDACNNAEFLL 738
A+ ++ + + +LQ + ++ +I S + E++PT+++ + N LL
Sbjct: 114 ASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLEPSESLEENQRNLL 173
Query: 739 MILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPAL 798
+ ++ +I +S P +R +C CL + ++P V +FLR I PA+
Sbjct: 174 QMTEKFFHAIISSSSEFPPQLRSVCHCLYQVVSQRFPQNSI---GAVGSAMFLRFINPAI 230
Query: 799 VEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKE-RMV 857
V P ++ + PPP +R L +++K LQ++AN V F KE +M N F+ N +
Sbjct: 231 VSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLF-TKEEHMRPFNDFVKSNFDAARR 289
Query: 858 VFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHI 892
FLD S+ P + N +++F + LH +
Sbjct: 290 FFLDIASDCPT--SDAVNHSLSFISDGNVLALHRL 322
>M38107-1|AAB59558.1| 2503|Homo sapiens neurofibromatosis protein type
1 protein.
Length = 2503
Score = 93.9 bits (223), Expect = 2e-18
Identities = 72/275 (26%), Positives = 129/275 (46%), Gaps = 12/275 (4%)
Query: 624 IPAVKALADLCRTDR-QPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASL 682
+P ALA++ + LA ++ F +L + EV +TLFRG SL
Sbjct: 887 LPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSL 946
Query: 683 ATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQ----TAELNPTKMDSPDDACNNAEFLL 738
A+ ++ + + +LQ + ++ +I S + E++PT+++ + N LL
Sbjct: 947 ASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLEPSESLEENQRNLL 1006
Query: 739 MILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPAL 798
+ ++ +I +S P +R +C CL + ++P V +FLR I PA+
Sbjct: 1007 QMTEKFFHAIISSSSEFPPQLRSVCHCLYQVVSQRFPQNSI---GAVGSAMFLRFINPAI 1063
Query: 799 VEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKE-RMV 857
V P ++ + PPP +R L +++K LQ++AN V F KE +M N F+ N +
Sbjct: 1064 VSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLF-TKEEHMRPFNDFVKSNFDAARR 1122
Query: 858 VFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHI 892
FLD S+ P + N +++F + LH +
Sbjct: 1123 FFLDIASDCPT--SDAVNHSLSFISDGNVLALHRL 1155
>M38106-1|AAA74897.1| 2485|Homo sapiens neurofibromatosis type 1
protein protein.
Length = 2485
Score = 93.9 bits (223), Expect = 2e-18
Identities = 72/275 (26%), Positives = 129/275 (46%), Gaps = 12/275 (4%)
Query: 624 IPAVKALADLCRTDR-QPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASL 682
+P ALA++ + LA ++ F +L + EV +TLFRG SL
Sbjct: 887 LPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSL 946
Query: 683 ATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQ----TAELNPTKMDSPDDACNNAEFLL 738
A+ ++ + + +LQ + ++ +I S + E++PT+++ + N LL
Sbjct: 947 ASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLEPSESLEENQRNLL 1006
Query: 739 MILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPAL 798
+ ++ +I +S P +R +C CL + ++P V +FLR I PA+
Sbjct: 1007 QMTEKFFHAIISSSSEFPPQLRSVCHCLYQVVSQRFPQNSI---GAVGSAMFLRFINPAI 1063
Query: 799 VEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKE-RMV 857
V P ++ + PPP +R L +++K LQ++AN V F KE +M N F+ N +
Sbjct: 1064 VSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLF-TKEEHMRPFNDFVKSNFDAARR 1122
Query: 858 VFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHI 892
FLD S+ P + N +++F + LH +
Sbjct: 1123 FFLDIASDCPT--SDAVNHSLSFISDGNVLALHRL 1155
>AY796305-1|AAV50004.1| 2818|Homo sapiens neurofibromin 1
(neurofibromatosis, von Recklinghausen disease, Watson
disease) protein.
Length = 2818
Score = 93.9 bits (223), Expect = 2e-18
Identities = 72/275 (26%), Positives = 129/275 (46%), Gaps = 12/275 (4%)
Query: 624 IPAVKALADLCRTDR-QPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASL 682
+P ALA++ + LA ++ F +L + EV +TLFRG SL
Sbjct: 1221 LPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSL 1280
Query: 683 ATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQ----TAELNPTKMDSPDDACNNAEFLL 738
A+ ++ + + +LQ + ++ +I S + E++PT+++ + N LL
Sbjct: 1281 ASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLEPSESLEENQRNLL 1340
Query: 739 MILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPAL 798
+ ++ +I +S P +R +C CL + ++P V +FLR I PA+
Sbjct: 1341 QMTEKFFHAIISSSSEFPPQLRSVCHCLYQVVSQRFPQNSI---GAVGSAMFLRFINPAI 1397
Query: 799 VEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKE-RMV 857
V P ++ + PPP +R L +++K LQ++AN V F KE +M N F+ N +
Sbjct: 1398 VSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLF-TKEEHMRPFNDFVKSNFDAARR 1456
Query: 858 VFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHI 892
FLD S+ P + N +++F + LH +
Sbjct: 1457 FFLDIASDCPT--SDAVNHSLSFISDGNVLALHRL 1489
>AB209336-1|BAD92573.1| 968|Homo sapiens neurofibromin variant
protein.
Length = 968
Score = 93.9 bits (223), Expect = 2e-18
Identities = 72/275 (26%), Positives = 129/275 (46%), Gaps = 12/275 (4%)
Query: 624 IPAVKALADLCRTDR-QPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASL 682
+P ALA++ + LA ++ F +L + EV +TLFRG SL
Sbjct: 271 LPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSL 330
Query: 683 ATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQ----TAELNPTKMDSPDDACNNAEFLL 738
A+ ++ + + +LQ + ++ +I S + E++PT+++ + N LL
Sbjct: 331 ASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLEPSESLEENQRNLL 390
Query: 739 MILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPAL 798
+ ++ +I +S P +R +C CL + ++P V +FLR I PA+
Sbjct: 391 QMTEKFFHAIISSSSEFPPQLRSVCHCLYQVVSQRFPQNSI---GAVGSAMFLRFINPAI 447
Query: 799 VEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKE-RMV 857
V P ++ + PPP +R L +++K LQ++AN V F KE +M N F+ N +
Sbjct: 448 VSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLF-TKEEHMRPFNDFVKSNFDAARR 506
Query: 858 VFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHI 892
FLD S+ P + N +++F + LH +
Sbjct: 507 FFLDIASDCPT--SDAVNHSLSFISDGNVLALHRL 539
>U17690-1|AAB48380.1| 861|Homo sapiens neurofibromatosis 1 protein.
Length = 861
Score = 83.4 bits (197), Expect = 3e-15
Identities = 77/293 (26%), Positives = 134/293 (45%), Gaps = 27/293 (9%)
Query: 624 IPAVKALADLCRTDR-QPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASL 682
+P ALA++ + LA ++ F +L + EV +TLFRG SL
Sbjct: 471 LPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSL 530
Query: 683 ATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQ----TAELNPTKMDSPDDACNNAEFLL 738
A+ ++ + + +LQ + ++ +I S + E++PT+++ + N LL
Sbjct: 531 ASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLEPSESLEENQRNLL 590
Query: 739 MILDQITLSIFTSPEACPKPVRYLCGCLQRA--------AVAKWPNE--------RFVRT 782
+ ++ +I +S P +R +C CL +A A K E RF +
Sbjct: 591 QMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQN 650
Query: 783 RV--VSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEP 840
+ V +FLR I PA+V P ++ + PPP +R L +++K LQ++AN V F KE
Sbjct: 651 SIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLF-TKEE 709
Query: 841 YMEVVNPFILKNKE-RMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHI 892
+M N F+ N + FLD S+ P + N +++F + LH +
Sbjct: 710 HMRPFNDFVKSNFDAARRFFLDIASDCPT--SDAVNHSLSFISDGNVLALHRL 760
>M89914-1|AAA59925.1| 2839|Homo sapiens neurofibromin protein.
Length = 2839
Score = 83.4 bits (197), Expect = 3e-15
Identities = 77/293 (26%), Positives = 134/293 (45%), Gaps = 27/293 (9%)
Query: 624 IPAVKALADLCRTDR-QPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASL 682
+P ALA++ + LA ++ F +L + EV +TLFRG SL
Sbjct: 1221 LPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSL 1280
Query: 683 ATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQ----TAELNPTKMDSPDDACNNAEFLL 738
A+ ++ + + +LQ + ++ +I S + E++PT+++ + N LL
Sbjct: 1281 ASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLEPSESLEENQRNLL 1340
Query: 739 MILDQITLSIFTSPEACPKPVRYLCGCLQRA--------AVAKWPNE--------RFVRT 782
+ ++ +I +S P +R +C CL +A A K E RF +
Sbjct: 1341 QMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQN 1400
Query: 783 RV--VSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEP 840
+ V +FLR I PA+V P ++ + PPP +R L +++K LQ++AN V F KE
Sbjct: 1401 SIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLF-TKEE 1459
Query: 841 YMEVVNPFILKNKE-RMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHI 892
+M N F+ N + FLD S+ P + N +++F + LH +
Sbjct: 1460 HMRPFNDFVKSNFDAARRFFLDIASDCPT--SDAVNHSLSFISDGNVLALHRL 1510
>M60915-1|AAA59921.1| 399|Homo sapiens neurofibromatosis protein
type 1 protein.
Length = 399
Score = 83.4 bits (197), Expect = 3e-15
Identities = 77/293 (26%), Positives = 134/293 (45%), Gaps = 27/293 (9%)
Query: 624 IPAVKALADLCRTDR-QPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASL 682
+P ALA++ + LA ++ F +L + EV +TLFRG SL
Sbjct: 54 LPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSL 113
Query: 683 ATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQ----TAELNPTKMDSPDDACNNAEFLL 738
A+ ++ + + +LQ + ++ +I S + E++PT+++ + N LL
Sbjct: 114 ASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLEPSESLEENQRNLL 173
Query: 739 MILDQITLSIFTSPEACPKPVRYLCGCLQRA--------AVAKWPNE--------RFVRT 782
+ ++ +I +S P +R +C CL +A A K E RF +
Sbjct: 174 QMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQN 233
Query: 783 RV--VSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEP 840
+ V +FLR I PA+V P ++ + PPP +R L +++K LQ++AN V F KE
Sbjct: 234 SIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLF-TKEE 292
Query: 841 YMEVVNPFILKNKE-RMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHI 892
+M N F+ N + FLD S+ P + N +++F + LH +
Sbjct: 293 HMRPFNDFVKSNFDAARRFFLDIASDCPT--SDAVNHSLSFISDGNVLALHRL 343
>CR450363-1|CAG29359.1| 217|Homo sapiens GRB2 protein.
Length = 217
Score = 69.3 bits (162), Expect = 6e-11
Identities = 45/163 (27%), Positives = 75/163 (46%), Gaps = 6/163 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDYY 124
W+ G++ R +EE L G++L+RES+ PG + LS + HF++ G Y+
Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTDELT 184
+ +F+SL ELV + H S + R + V A+ + D EL
Sbjct: 120 LWVVKFNSLNELVDY--HRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQED-GELG 176
Query: 185 FQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
F++GD V ++ G W H G+ GM R V ++ ++
Sbjct: 177 FRRGDFIHVMDNSGPNWWKGACH--GQTGMFPRNYVTPVNRNV 217
Score = 66.5 bits (155), Expect = 4e-10
Identities = 45/147 (30%), Positives = 76/147 (51%), Gaps = 12/147 (8%)
Query: 170 AILPYT-KMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
AI Y K DEL+F++GDI V N+ D W A G+ G I + +E +
Sbjct: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQ-NWYKAELNGKDGFIPKNYIE-----MK 56
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKK 287
P+ WF +++A +ML K G+FL+R S+++PGD+SL N +Q F++ +
Sbjct: 57 PHP---WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRD 113
Query: 288 GV-RYLMGGRTFECLDAVINRYRKEQI 313
G +Y + F L+ +++ +R +
Sbjct: 114 GAGKYFLWVVKFNSLNELVDYHRSTSV 140
>X62852-1|CAA44664.1| 160|Homo sapiens ash protein protein.
Length = 160
Score = 66.5 bits (155), Expect = 4e-10
Identities = 44/163 (26%), Positives = 74/163 (45%), Gaps = 6/163 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDYY 124
W+ G++ R +EE L G++L+RES+ PG + LS + HF++ G Y+
Sbjct: 3 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 62
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTDELT 184
+ +F+SL ELV + H S + R + V A+ + D EL
Sbjct: 63 LWVVKFNSLNELVDY--HRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQED-GELG 119
Query: 185 FQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
F++GD V ++ W H G+ GM R V ++ ++
Sbjct: 120 FRRGDFIHVMDNSDPNWWKGACH--GQTGMFPRNYVTPVNRNV 160
Score = 50.8 bits (116), Expect = 2e-05
Identities = 24/81 (29%), Positives = 46/81 (56%), Gaps = 2/81 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV-RYL 292
WF +++A +ML K G+FL+R S+++PGD+SL N +Q F++ + G +Y
Sbjct: 3 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 62
Query: 293 MGGRTFECLDAVINRYRKEQI 313
+ F L+ +++ +R +
Sbjct: 63 LWVVKFNSLNELVDYHRSTSV 83
>M96995-1|AAA58448.1| 217|Homo sapiens epidermal growth factor
receptor-binding protein GRB2 protein.
Length = 217
Score = 66.5 bits (155), Expect = 4e-10
Identities = 45/147 (30%), Positives = 76/147 (51%), Gaps = 12/147 (8%)
Query: 170 AILPYT-KMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
AI Y K DEL+F++GDI V N+ D W A G+ G I + +E +
Sbjct: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQ-NWYKAELNGKDGFIPKNYIE-----MK 56
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKK 287
P+ WF +++A +ML K G+FL+R S+++PGD+SL N +Q F++ +
Sbjct: 57 PHP---WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRD 113
Query: 288 GV-RYLMGGRTFECLDAVINRYRKEQI 313
G +Y + F L+ +++ +R +
Sbjct: 114 GAGKYFLWVVKFNSLNELVDYHRSTSV 140
Score = 66.5 bits (155), Expect = 4e-10
Identities = 44/163 (26%), Positives = 74/163 (45%), Gaps = 6/163 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDYY 124
W+ G++ R +EE L G++L+RES+ PG + LS + HF++ G Y+
Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTDELT 184
+ +F+SL ELV + H S + R + V A+ + D EL
Sbjct: 120 LWVVKFNSLNELVDY--HRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQED-GELG 176
Query: 185 FQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
F++GD V ++ W H G+ GM R V ++ ++
Sbjct: 177 FRRGDFIHVMDNSDPNWWKGACH--GQTGMFPRNYVTPVNRNV 217
>CR541942-1|CAG46740.1| 217|Homo sapiens GRB2 protein.
Length = 217
Score = 66.5 bits (155), Expect = 4e-10
Identities = 45/147 (30%), Positives = 76/147 (51%), Gaps = 12/147 (8%)
Query: 170 AILPYT-KMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
AI Y K DEL+F++GDI V N+ D W A G+ G I + +E +
Sbjct: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQ-NWYKAELNGKDGFIPKNYIE-----MK 56
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKK 287
P+ WF +++A +ML K G+FL+R S+++PGD+SL N +Q F++ +
Sbjct: 57 PHP---WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRD 113
Query: 288 GV-RYLMGGRTFECLDAVINRYRKEQI 313
G +Y + F L+ +++ +R +
Sbjct: 114 GAGKYFLWVVKFNSLNELVDYHRSTSV 140
Score = 66.5 bits (155), Expect = 4e-10
Identities = 44/163 (26%), Positives = 74/163 (45%), Gaps = 6/163 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDYY 124
W+ G++ R +EE L G++L+RES+ PG + LS + HF++ G Y+
Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTDELT 184
+ +F+SL ELV + H S + R + V A+ + D EL
Sbjct: 120 LWVVKFNSLNELVDY--HRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQED-GELG 176
Query: 185 FQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
F++GD V ++ W H G+ GM R V ++ ++
Sbjct: 177 FRRGDFIHVMDNSDPNWWKGACH--GQTGMFPRNYVTPVNRNV 217
>BC000631-1|AAH00631.1| 217|Homo sapiens growth factor
receptor-bound protein 2 protein.
Length = 217
Score = 66.5 bits (155), Expect = 4e-10
Identities = 45/147 (30%), Positives = 76/147 (51%), Gaps = 12/147 (8%)
Query: 170 AILPYT-KMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
AI Y K DEL+F++GDI V N+ D W A G+ G I + +E +
Sbjct: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQ-NWYKAELNGKDGFIPKNYIE-----MK 56
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKK 287
P+ WF +++A +ML K G+FL+R S+++PGD+SL N +Q F++ +
Sbjct: 57 PHP---WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRD 113
Query: 288 GV-RYLMGGRTFECLDAVINRYRKEQI 313
G +Y + F L+ +++ +R +
Sbjct: 114 GAGKYFLWVVKFNSLNELVDYHRSTSV 140
Score = 66.5 bits (155), Expect = 4e-10
Identities = 44/163 (26%), Positives = 74/163 (45%), Gaps = 6/163 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDYY 124
W+ G++ R +EE L G++L+RES+ PG + LS + HF++ G Y+
Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTDELT 184
+ +F+SL ELV + H S + R + V A+ + D EL
Sbjct: 120 LWVVKFNSLNELVDY--HRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQED-GELG 176
Query: 185 FQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
F++GD V ++ W H G+ GM R V ++ ++
Sbjct: 177 FRRGDFIHVMDNSDPNWWKGACH--GQTGMFPRNYVTPVNRNV 217
>AF498925-1|AAM21073.1| 217|Homo sapiens growth factor
receptor-bound protein 2 protein.
Length = 217
Score = 66.5 bits (155), Expect = 4e-10
Identities = 45/147 (30%), Positives = 76/147 (51%), Gaps = 12/147 (8%)
Query: 170 AILPYT-KMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
AI Y K DEL+F++GDI V N+ D W A G+ G I + +E +
Sbjct: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQ-NWYKAELNGKDGFIPKNYIE-----MK 56
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKK 287
P+ WF +++A +ML K G+FL+R S+++PGD+SL N +Q F++ +
Sbjct: 57 PHP---WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRD 113
Query: 288 GV-RYLMGGRTFECLDAVINRYRKEQI 313
G +Y + F L+ +++ +R +
Sbjct: 114 GAGKYFLWVVKFNSLNELVDYHRSTSV 140
Score = 66.5 bits (155), Expect = 4e-10
Identities = 44/163 (26%), Positives = 74/163 (45%), Gaps = 6/163 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDYY 124
W+ G++ R +EE L G++L+RES+ PG + LS + HF++ G Y+
Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTDELT 184
+ +F+SL ELV + H S + R + V A+ + D EL
Sbjct: 120 LWVVKFNSLNELVDY--HRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQED-GELG 176
Query: 185 FQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
F++GD V ++ W H G+ GM R V ++ ++
Sbjct: 177 FRRGDFIHVMDNSDPNWWKGACH--GQTGMFPRNYVTPVNRNV 217
>AF063618-1|AAC72075.1| 217|Homo sapiens growth factor
receptor-bound protein 2 protein.
Length = 217
Score = 66.5 bits (155), Expect = 4e-10
Identities = 45/147 (30%), Positives = 76/147 (51%), Gaps = 12/147 (8%)
Query: 170 AILPYT-KMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
AI Y K DEL+F++GDI V N+ D W A G+ G I + +E +
Sbjct: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQ-NWYKAELNGKDGFIPKNYIE-----MK 56
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKK 287
P+ WF +++A +ML K G+FL+R S+++PGD+SL N +Q F++ +
Sbjct: 57 PHP---WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRD 113
Query: 288 GV-RYLMGGRTFECLDAVINRYRKEQI 313
G +Y + F L+ +++ +R +
Sbjct: 114 GAGKYFLWVVKFNSLNELVDYHRSTSV 140
Score = 66.5 bits (155), Expect = 4e-10
Identities = 44/163 (26%), Positives = 74/163 (45%), Gaps = 6/163 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDYY 124
W+ G++ R +EE L G++L+RES+ PG + LS + HF++ G Y+
Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTDELT 184
+ +F+SL ELV + H S + R + V A+ + D EL
Sbjct: 120 LWVVKFNSLNELVDY--HRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQED-GELG 176
Query: 185 FQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
F++GD V ++ W H G+ GM R V ++ ++
Sbjct: 177 FRRGDFIHVMDNSDPNWWKGACH--GQTGMFPRNYVTPVNRNV 217
>U52518-1|AAC50541.1| 217|Homo sapiens Grb2-related adaptor protein
protein.
Length = 217
Score = 64.9 bits (151), Expect = 1e-09
Identities = 44/157 (28%), Positives = 69/157 (43%), Gaps = 4/157 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDYY 124
WY GR+ R +EE L + G++L+RES+ PG + +S + HF++ G Y+
Sbjct: 60 WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYF 119
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTDELT 184
+ +F+SL ELV FY + KR+ A ++ D +L+
Sbjct: 120 LWEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEPLLKSPGACFAQAQFDFSAQ-DPSQLS 178
Query: 185 FQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVE 221
F++GDI V W W G G R V+
Sbjct: 179 FRRGDIIEVLERPDPHW-W-RGRSCGRVGFFPRSYVQ 213
Score = 62.5 bits (145), Expect = 7e-09
Identities = 38/139 (27%), Positives = 73/139 (52%), Gaps = 11/139 (7%)
Query: 179 DTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHP 238
++DEL F KGD + N M D W A G +G I + + + P+ W+
Sbjct: 13 ESDELAFNKGDTLKILN-MEDDQNWYKAELRGVEGFIPKNYIR-----VKPHP---WYSG 63
Query: 239 NCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV-RYLMGGR 296
++ A ++L+K G+FL+R S++SPG++S+ + +Q+Q F++ ++ +Y +
Sbjct: 64 RISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFLWEE 123
Query: 297 TFECLDAVINRYRKEQIVE 315
F L+ +++ YR I +
Sbjct: 124 KFNSLNELVDFYRTTTIAK 142
>CR541966-1|CAG46764.1| 217|Homo sapiens GRAP protein.
Length = 217
Score = 64.9 bits (151), Expect = 1e-09
Identities = 44/157 (28%), Positives = 69/157 (43%), Gaps = 4/157 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDYY 124
WY GR+ R +EE L + G++L+RES+ PG + +S + HF++ G Y+
Sbjct: 60 WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYF 119
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTDELT 184
+ +F+SL ELV FY + KR+ A ++ D +L+
Sbjct: 120 LWEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEPLLKSPGACFAQAQFDFSAQ-DPSQLS 178
Query: 185 FQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVE 221
F++GDI V W W G G R V+
Sbjct: 179 FRRGDIIEVLERPDPHW-W-RGRSCGRVGFFPRSYVQ 213
Score = 62.5 bits (145), Expect = 7e-09
Identities = 38/139 (27%), Positives = 73/139 (52%), Gaps = 11/139 (7%)
Query: 179 DTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHP 238
++DEL F KGD + N M D W A G +G I + + + P+ W+
Sbjct: 13 ESDELAFNKGDTLKILN-MEDDQNWYKAELRGVEGFIPKNYIR-----VKPHP---WYSG 63
Query: 239 NCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV-RYLMGGR 296
++ A ++L+K G+FL+R S++SPG++S+ + +Q+Q F++ ++ +Y +
Sbjct: 64 RISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFLWEE 123
Query: 297 TFECLDAVINRYRKEQIVE 315
F L+ +++ YR I +
Sbjct: 124 KFNSLNELVDFYRTTTIAK 142
>CR541941-1|CAG46739.1| 217|Homo sapiens GRAP protein.
Length = 217
Score = 64.9 bits (151), Expect = 1e-09
Identities = 44/157 (28%), Positives = 69/157 (43%), Gaps = 4/157 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDYY 124
WY GR+ R +EE L + G++L+RES+ PG + +S + HF++ G Y+
Sbjct: 60 WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYF 119
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTDELT 184
+ +F+SL ELV FY + KR+ A ++ D +L+
Sbjct: 120 LWEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEPLLKSPGACFAQAQFDFSAQ-DPSQLS 178
Query: 185 FQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVE 221
F++GDI V W W G G R V+
Sbjct: 179 FRRGDIIEVLERPDPHW-W-RGRSCGRVGFFPRSYVQ 213
Score = 62.5 bits (145), Expect = 7e-09
Identities = 38/139 (27%), Positives = 73/139 (52%), Gaps = 11/139 (7%)
Query: 179 DTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHP 238
++DEL F KGD + N M D W A G +G I + + + P+ W+
Sbjct: 13 ESDELAFNKGDTLKILN-MEDDQNWYKAELRGVEGFIPKNYIR-----VKPHP---WYSG 63
Query: 239 NCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV-RYLMGGR 296
++ A ++L+K G+FL+R S++SPG++S+ + +Q+Q F++ ++ +Y +
Sbjct: 64 RISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFLWEE 123
Query: 297 TFECLDAVINRYRKEQIVE 315
F L+ +++ YR I +
Sbjct: 124 KFNSLNELVDFYRTTTIAK 142
>BT019981-1|AAV38784.1| 217|Homo sapiens GRB2-related adaptor
protein protein.
Length = 217
Score = 64.9 bits (151), Expect = 1e-09
Identities = 44/157 (28%), Positives = 69/157 (43%), Gaps = 4/157 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDYY 124
WY GR+ R +EE L + G++L+RES+ PG + +S + HF++ G Y+
Sbjct: 60 WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYF 119
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTDELT 184
+ +F+SL ELV FY + KR+ A ++ D +L+
Sbjct: 120 LWEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEPLLKSPGACFAQAQFDFSAQ-DPSQLS 178
Query: 185 FQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVE 221
F++GDI V W W G G R V+
Sbjct: 179 FRRGDIIEVLERPDPHW-W-RGRSCGRVGFFPRSYVQ 213
Score = 62.5 bits (145), Expect = 7e-09
Identities = 38/139 (27%), Positives = 73/139 (52%), Gaps = 11/139 (7%)
Query: 179 DTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHP 238
++DEL F KGD + N M D W A G +G I + + + P+ W+
Sbjct: 13 ESDELAFNKGDTLKILN-MEDDQNWYKAELRGVEGFIPKNYIR-----VKPHP---WYSG 63
Query: 239 NCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV-RYLMGGR 296
++ A ++L+K G+FL+R S++SPG++S+ + +Q+Q F++ ++ +Y +
Sbjct: 64 RISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFLWEE 123
Query: 297 TFECLDAVINRYRKEQIVE 315
F L+ +++ YR I +
Sbjct: 124 KFNSLNELVDFYRTTTIAK 142
>BC063035-1|AAH63035.1| 217|Homo sapiens GRB2-related adaptor
protein protein.
Length = 217
Score = 64.9 bits (151), Expect = 1e-09
Identities = 44/157 (28%), Positives = 69/157 (43%), Gaps = 4/157 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDYY 124
WY GR+ R +EE L + G++L+RES+ PG + +S + HF++ G Y+
Sbjct: 60 WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYF 119
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTDELT 184
+ +F+SL ELV FY + KR+ A ++ D +L+
Sbjct: 120 LWEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEPLLKSPGACFAQAQFDFSAQ-DPSQLS 178
Query: 185 FQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVE 221
F++GDI V W W G G R V+
Sbjct: 179 FRRGDIIEVLERPDPHW-W-RGRSCGRVGFFPRSYVQ 213
Score = 62.5 bits (145), Expect = 7e-09
Identities = 38/139 (27%), Positives = 73/139 (52%), Gaps = 11/139 (7%)
Query: 179 DTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHP 238
++DEL F KGD + N M D W A G +G I + + + P+ W+
Sbjct: 13 ESDELAFNKGDTLKILN-MEDDQNWYKAELRGVEGFIPKNYIR-----VKPHP---WYSG 63
Query: 239 NCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV-RYLMGGR 296
++ A ++L+K G+FL+R S++SPG++S+ + +Q+Q F++ ++ +Y +
Sbjct: 64 RISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFLWEE 123
Query: 297 TFECLDAVINRYRKEQIVE 315
F L+ +++ YR I +
Sbjct: 124 KFNSLNELVDFYRTTTIAK 142
>BC035856-1|AAH35856.1| 217|Homo sapiens GRB2-related adaptor
protein protein.
Length = 217
Score = 64.9 bits (151), Expect = 1e-09
Identities = 44/157 (28%), Positives = 69/157 (43%), Gaps = 4/157 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDYY 124
WY GR+ R +EE L + G++L+RES+ PG + +S + HF++ G Y+
Sbjct: 60 WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYF 119
Query: 125 IGGRQFDSLTELVGFYSHCSDLLKRERLXXXXXXXXXXNDKKRVVAILPYTKMPDTDELT 184
+ +F+SL ELV FY + KR+ A ++ D +L+
Sbjct: 120 LWEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEPLLKSPGACFAQAQFDFSAQ-DPSQLS 178
Query: 185 FQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVE 221
F++GDI V W W G G R V+
Sbjct: 179 FRRGDIIEVLERPDPHW-W-RGRSCGRVGFFPRSYVQ 213
Score = 62.5 bits (145), Expect = 7e-09
Identities = 38/139 (27%), Positives = 73/139 (52%), Gaps = 11/139 (7%)
Query: 179 DTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHP 238
++DEL F KGD + N M D W A G +G I + + + P+ W+
Sbjct: 13 ESDELAFNKGDTLKILN-MEDDQNWYKAELRGVEGFIPKNYIR-----VKPHP---WYSG 63
Query: 239 NCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV-RYLMGGR 296
++ A ++L+K G+FL+R S++SPG++S+ + +Q+Q F++ ++ +Y +
Sbjct: 64 RISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFLWEE 123
Query: 297 TFECLDAVINRYRKEQIVE 315
F L+ +++ YR I +
Sbjct: 124 KFNSLNELVDFYRTTTIAK 142
>L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 63.3 bits (147), Expect = 4e-09
Identities = 40/139 (28%), Positives = 63/139 (45%), Gaps = 4/139 (2%)
Query: 178 PDTDELTFQKGDIFFVHNDMGD-GWLWVTAHRTGEQGMIFRELVEDLDP-SIDPN-TVFS 234
P EL F+KGD+ + + W V H +G++G++ + D + S DP ++
Sbjct: 62 PKPGELAFRKGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALRDGEALSADPKLSLMP 121
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMG 294
WFH + EAV L G FLVR S PGDY L + +R+ + +
Sbjct: 122 WFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTID 181
Query: 295 GRTFEC-LDAVINRYRKEQ 312
F C L ++ Y K++
Sbjct: 182 EAVFFCNLMDMVEHYSKDK 200
Score = 40.7 bits (91), Expect = 0.023
Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
W+HG++ + ++L + G +LVRES R PG YVL + H+R+ G I
Sbjct: 122 WFHGKISGQEAVQQL-QPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTI 180
Query: 126 GGRQ-FDSLTELVGFYS 141
F +L ++V YS
Sbjct: 181 DEAVFFCNLMDMVEHYS 197
>S71669-1|AAB30995.1| 465|Homo sapiens lsk protein.
Length = 465
Score = 62.9 bits (146), Expect = 5e-09
Identities = 54/206 (26%), Positives = 86/206 (41%), Gaps = 8/206 (3%)
Query: 178 PDTDELTFQKGDIFFVHNDMGD-GWLWVTAHRTGEQGMIFRELVEDLDP-SIDPN-TVFS 234
P EL F+KGD+ + + W V H +G++G++ + + + S DP ++
Sbjct: 21 PKPGELAFRKGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALREREALSADPKLSLMP 80
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMG 294
WFH + EAV L G FLVR S PGDY L + +R+ + +
Sbjct: 81 WFHGKISGQEAVQQLQPPEDGLFLVRESGGHPGDYVLCVTFGRDVIHYRVLHRDGHLTID 140
Query: 295 GRTFEC-LDAVINRYRKEQIVEGHTLGQPLIAEG-HTIEPQQSTTGAAAEKIYATLRECR 352
F C L ++ Y K++ L +P G + E + + G + TL
Sbjct: 141 EAVFFCNLMDMVEHYSKDKGAICTKLVRPKRKHGTKSAEEELARAGWLLNLQHLTLGA-- 198
Query: 353 DQIGLKKTKGIKHYGYLNKKSDKGAK 378
QIG + + YL +K K K
Sbjct: 199 -QIGEGEFGAVLQGEYLGQKCVKNIK 223
Score = 42.7 bits (96), Expect = 0.006
Identities = 29/92 (31%), Positives = 46/92 (50%), Gaps = 5/92 (5%)
Query: 54 ERQAVLAPPETE---WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTG 110
ER+A+ A P+ W+HG++ + ++L + G +LVRES PG YVL
Sbjct: 66 EREALSADPKLSLMPWFHGKISGQEAVQQL-QPPEDGLFLVRESGGHPGDYVLCVTFGRD 124
Query: 111 INHFRITAVCGDYYIGGRQ-FDSLTELVGFYS 141
+ H+R+ G I F +L ++V YS
Sbjct: 125 VIHYRVLHRDGHLTIDEAVFFCNLMDMVEHYS 156
>X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein.
Length = 507
Score = 62.5 bits (145), Expect = 7e-09
Identities = 39/139 (28%), Positives = 63/139 (45%), Gaps = 4/139 (2%)
Query: 178 PDTDELTFQKGDIFFVHNDMGD-GWLWVTAHRTGEQGMIFRELVEDLDP-SIDPN-TVFS 234
P EL F+KGD+ + + W V H +G++G++ + + + S DP ++
Sbjct: 62 PKPGELAFRKGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALREREALSADPKLSLMP 121
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMG 294
WFH + EAV L G FLVR S PGDY L + +R+ + +
Sbjct: 122 WFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTID 181
Query: 295 GRTFEC-LDAVINRYRKEQ 312
F C L ++ Y K++
Sbjct: 182 EAVFFCNLMDMVEHYSKDK 200
Score = 44.8 bits (101), Expect = 0.001
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 5/92 (5%)
Query: 54 ERQAVLAPPETE---WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTG 110
ER+A+ A P+ W+HG++ + ++L + G +LVRES R PG YVL
Sbjct: 107 EREALSADPKLSLMPWFHGKISGQEAVQQL-QPPEDGLFLVRESARHPGDYVLCVSFGRD 165
Query: 111 INHFRITAVCGDYYIGGRQ-FDSLTELVGFYS 141
+ H+R+ G I F +L ++V YS
Sbjct: 166 VIHYRVLHRDGHLTIDEAVFFCNLMDMVEHYS 197
>S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 62.5 bits (145), Expect = 7e-09
Identities = 39/139 (28%), Positives = 63/139 (45%), Gaps = 4/139 (2%)
Query: 178 PDTDELTFQKGDIFFVHNDMGD-GWLWVTAHRTGEQGMIFRELVEDLDP-SIDPN-TVFS 234
P EL F+KGD+ + + W V H +G++G++ + + + S DP ++
Sbjct: 62 PKPGELAFRKGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALREREALSADPKLSLMP 121
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMG 294
WFH + EAV L G FLVR S PGDY L + +R+ + +
Sbjct: 122 WFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTID 181
Query: 295 GRTFEC-LDAVINRYRKEQ 312
F C L ++ Y K++
Sbjct: 182 EAVFFCNLMDMVEHYSKDK 200
Score = 44.8 bits (101), Expect = 0.001
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 5/92 (5%)
Query: 54 ERQAVLAPPETE---WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTG 110
ER+A+ A P+ W+HG++ + ++L + G +LVRES R PG YVL
Sbjct: 107 EREALSADPKLSLMPWFHGKISGQEAVQQL-QPPEDGLFLVRESARHPGDYVLCVSFGRD 165
Query: 111 INHFRITAVCGDYYIGGRQ-FDSLTELVGFYS 141
+ H+R+ G I F +L ++V YS
Sbjct: 166 VIHYRVLHRDGHLTIDEAVFFCNLMDMVEHYS 197
>BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 62.5 bits (145), Expect = 7e-09
Identities = 39/139 (28%), Positives = 63/139 (45%), Gaps = 4/139 (2%)
Query: 178 PDTDELTFQKGDIFFVHNDMGD-GWLWVTAHRTGEQGMIFRELVEDLDP-SIDPN-TVFS 234
P EL F+KGD+ + + W V H +G++G++ + + + S DP ++
Sbjct: 62 PKPGELAFRKGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALREREALSADPKLSLMP 121
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMG 294
WFH + EAV L G FLVR S PGDY L + +R+ + +
Sbjct: 122 WFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTID 181
Query: 295 GRTFEC-LDAVINRYRKEQ 312
F C L ++ Y K++
Sbjct: 182 EAVFFCNLMDMVEHYSKDK 200
Score = 44.8 bits (101), Expect = 0.001
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 5/92 (5%)
Query: 54 ERQAVLAPPETE---WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTG 110
ER+A+ A P+ W+HG++ + ++L + G +LVRES R PG YVL
Sbjct: 107 EREALSADPKLSLMPWFHGKISGQEAVQQL-QPPEDGLFLVRESARHPGDYVLCVSFGRD 165
Query: 111 INHFRITAVCGDYYIGGRQ-FDSLTELVGFYS 141
+ H+R+ G I F +L ++V YS
Sbjct: 166 VIHYRVLHRDGHLTIDEAVFFCNLMDMVEHYS 197
>BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 62.5 bits (145), Expect = 7e-09
Identities = 39/139 (28%), Positives = 63/139 (45%), Gaps = 4/139 (2%)
Query: 178 PDTDELTFQKGDIFFVHNDMGD-GWLWVTAHRTGEQGMIFRELVEDLDP-SIDPN-TVFS 234
P EL F+KGD+ + + W V H +G++G++ + + + S DP ++
Sbjct: 62 PKPGELAFRKGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALREREALSADPKLSLMP 121
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMG 294
WFH + EAV L G FLVR S PGDY L + +R+ + +
Sbjct: 122 WFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTID 181
Query: 295 GRTFEC-LDAVINRYRKEQ 312
F C L ++ Y K++
Sbjct: 182 EAVFFCNLMDMVEHYSKDK 200
Score = 44.8 bits (101), Expect = 0.001
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 5/92 (5%)
Query: 54 ERQAVLAPPETE---WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTG 110
ER+A+ A P+ W+HG++ + ++L + G +LVRES R PG YVL
Sbjct: 107 EREALSADPKLSLMPWFHGKISGQEAVQQL-QPPEDGLFLVRESARHPGDYVLCVSFGRD 165
Query: 111 INHFRITAVCGDYYIGGRQ-FDSLTELVGFYS 141
+ H+R+ G I F +L ++V YS
Sbjct: 166 VIHYRVLHRDGHLTIDEAVFFCNLMDMVEHYS 197
>AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein.
Length = 507
Score = 62.5 bits (145), Expect = 7e-09
Identities = 39/139 (28%), Positives = 63/139 (45%), Gaps = 4/139 (2%)
Query: 178 PDTDELTFQKGDIFFVHNDMGD-GWLWVTAHRTGEQGMIFRELVEDLDP-SIDPN-TVFS 234
P EL F+KGD+ + + W V H +G++G++ + + + S DP ++
Sbjct: 62 PKPGELAFRKGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALREREALSADPKLSLMP 121
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMG 294
WFH + EAV L G FLVR S PGDY L + +R+ + +
Sbjct: 122 WFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTID 181
Query: 295 GRTFEC-LDAVINRYRKEQ 312
F C L ++ Y K++
Sbjct: 182 EAVFFCNLMDMVEHYSKDK 200
Score = 44.8 bits (101), Expect = 0.001
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 5/92 (5%)
Query: 54 ERQAVLAPPETE---WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTG 110
ER+A+ A P+ W+HG++ + ++L + G +LVRES R PG YVL
Sbjct: 107 EREALSADPKLSLMPWFHGKISGQEAVQQL-QPPEDGLFLVRESARHPGDYVLCVSFGRD 165
Query: 111 INHFRITAVCGDYYIGGRQ-FDSLTELVGFYS 141
+ H+R+ G I F +L ++V YS
Sbjct: 166 VIHYRVLHRDGHLTIDEAVFFCNLMDMVEHYS 197
>X70766-1|CAA50045.1| 593|Homo sapiens protein-tyrosine phosphatase
protein.
Length = 593
Score = 61.3 bits (142), Expect = 2e-08
Identities = 31/76 (40%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFHPN T EA ++L+ G GSFL RPS ++PGD++L N + +I+ G Y L
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDL 65
Query: 293 MGGRTFECLDAVINRY 308
GG F L ++ Y
Sbjct: 66 YGGEKFATLAELVQYY 81
Score = 55.2 bits (127), Expect = 1e-06
Identities = 34/91 (37%), Positives = 45/91 (49%), Gaps = 11/91 (12%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYL----------GRTG 110
P W+HG L +E+ L K GS+LVRES PG +VLS G++
Sbjct: 107 PTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSK 166
Query: 111 INHFRITAVCGDYYI-GGRQFDSLTELVGFY 140
+ H I Y + GG +FDSLT+LV Y
Sbjct: 167 VTHVMIRCQELKYDVGGGERFDSLTDLVEHY 197
Score = 52.4 bits (120), Expect = 7e-06
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 3/87 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H + +E L GS+L R S PG + LS + H +I GDYY
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNT-GDYYD 64
Query: 125 -IGGRQFDSLTELVGFYSHCSDLLKRE 150
GG +F +L ELV +Y LK +
Sbjct: 65 LYGGEKFATLAELVQYYMEHHGQLKEK 91
Score = 46.0 bits (104), Expect = 6e-04
Identities = 42/135 (31%), Positives = 62/135 (45%), Gaps = 20/135 (14%)
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK 286
DP T WFH + + EA +L + G GSFLVR S + PGD+ L + K
Sbjct: 106 DP-TSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGK 164
Query: 287 KGVRYLM-----------GGRTFECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQS 335
V ++M GG F+ L ++ Y+K +VE TLG L ++ +
Sbjct: 165 SKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVE--TLGTVL-----QLKQPLN 217
Query: 336 TTGAAAEKIYATLRE 350
TT A +I + +RE
Sbjct: 218 TTRINAAEIESRVRE 232
>L07527-1|AAA17022.1| 593|Homo sapiens protein-tyrosine phosphatase
protein.
Length = 593
Score = 61.3 bits (142), Expect = 2e-08
Identities = 31/76 (40%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFHPN T EA ++L+ G GSFL RPS ++PGD++L N + +I+ G Y L
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDL 65
Query: 293 MGGRTFECLDAVINRY 308
GG F L ++ Y
Sbjct: 66 YGGEKFATLAELVQYY 81
Score = 55.2 bits (127), Expect = 1e-06
Identities = 34/91 (37%), Positives = 45/91 (49%), Gaps = 11/91 (12%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYL----------GRTG 110
P W+HG L +E+ L K GS+LVRES PG +VLS G++
Sbjct: 107 PTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSK 166
Query: 111 INHFRITAVCGDYYI-GGRQFDSLTELVGFY 140
+ H I Y + GG +FDSLT+LV Y
Sbjct: 167 VTHVMIRCQELKYDVGGGERFDSLTDLVEHY 197
Score = 52.4 bits (120), Expect = 7e-06
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 3/87 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H + +E L GS+L R S PG + LS + H +I GDYY
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNT-GDYYD 64
Query: 125 -IGGRQFDSLTELVGFYSHCSDLLKRE 150
GG +F +L ELV +Y LK +
Sbjct: 65 LYGGEKFATLAELVQYYMEHHGQLKEK 91
Score = 46.0 bits (104), Expect = 6e-04
Identities = 42/135 (31%), Positives = 62/135 (45%), Gaps = 20/135 (14%)
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK 286
DP T WFH + + EA +L + G GSFLVR S + PGD+ L + K
Sbjct: 106 DP-TSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGK 164
Query: 287 KGVRYLM-----------GGRTFECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQS 335
V ++M GG F+ L ++ Y+K +VE TLG L ++ +
Sbjct: 165 SKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVE--TLGTVL-----QLKQPLN 217
Query: 336 TTGAAAEKIYATLRE 350
TT A +I + +RE
Sbjct: 218 TTRINAAEIESRVRE 232
>L03535-1|AAA36611.1| 593|Homo sapiens phosphotyrosyl-protein
phosphatase protein.
Length = 593
Score = 61.3 bits (142), Expect = 2e-08
Identities = 31/76 (40%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFHPN T EA ++L+ G GSFL RPS ++PGD++L N + +I+ G Y L
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDL 65
Query: 293 MGGRTFECLDAVINRY 308
GG F L ++ Y
Sbjct: 66 YGGEKFATLAELVQYY 81
Score = 55.2 bits (127), Expect = 1e-06
Identities = 34/91 (37%), Positives = 45/91 (49%), Gaps = 11/91 (12%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYL----------GRTG 110
P W+HG L +E+ L K GS+LVRES PG +VLS G++
Sbjct: 107 PTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSK 166
Query: 111 INHFRITAVCGDYYI-GGRQFDSLTELVGFY 140
+ H I Y + GG +FDSLT+LV Y
Sbjct: 167 VTHVMIRCQELKYDVGGGERFDSLTDLVEHY 197
Score = 52.4 bits (120), Expect = 7e-06
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 3/87 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H + +E L GS+L R S PG + LS + H +I GDYY
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNT-GDYYD 64
Query: 125 -IGGRQFDSLTELVGFYSHCSDLLKRE 150
GG +F +L ELV +Y LK +
Sbjct: 65 LYGGEKFATLAELVQYYMEHHGQLKEK 91
Score = 46.0 bits (104), Expect = 6e-04
Identities = 42/135 (31%), Positives = 62/135 (45%), Gaps = 20/135 (14%)
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK 286
DP T WFH + + EA +L + G GSFLVR S + PGD+ L + K
Sbjct: 106 DP-TSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGK 164
Query: 287 KGVRYLM-----------GGRTFECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQS 335
V ++M GG F+ L ++ Y+K +VE TLG L ++ +
Sbjct: 165 SKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVE--TLGTVL-----QLKQPLN 217
Query: 336 TTGAAAEKIYATLRE 350
TT A +I + +RE
Sbjct: 218 TTRINAAEIESRVRE 232
>D13540-1|BAA02740.2| 593|Homo sapiens protein-tyrosine phosphatase
protein.
Length = 593
Score = 61.3 bits (142), Expect = 2e-08
Identities = 31/76 (40%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFHPN T EA ++L+ G GSFL RPS ++PGD++L N + +I+ G Y L
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDL 65
Query: 293 MGGRTFECLDAVINRY 308
GG F L ++ Y
Sbjct: 66 YGGEKFATLAELVQYY 81
Score = 55.2 bits (127), Expect = 1e-06
Identities = 34/91 (37%), Positives = 45/91 (49%), Gaps = 11/91 (12%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYL----------GRTG 110
P W+HG L +E+ L K GS+LVRES PG +VLS G++
Sbjct: 107 PTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSK 166
Query: 111 INHFRITAVCGDYYI-GGRQFDSLTELVGFY 140
+ H I Y + GG +FDSLT+LV Y
Sbjct: 167 VTHVMIRCQELKYDVGGGERFDSLTDLVEHY 197
Score = 52.4 bits (120), Expect = 7e-06
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 3/87 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H + +E L GS+L R S PG + LS + H +I GDYY
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNT-GDYYD 64
Query: 125 -IGGRQFDSLTELVGFYSHCSDLLKRE 150
GG +F +L ELV +Y LK +
Sbjct: 65 LYGGEKFATLAELVQYYMEHHGQLKEK 91
Score = 46.0 bits (104), Expect = 6e-04
Identities = 42/135 (31%), Positives = 62/135 (45%), Gaps = 20/135 (14%)
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK 286
DP T WFH + + EA +L + G GSFLVR S + PGD+ L + K
Sbjct: 106 DP-TSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGK 164
Query: 287 KGVRYLM-----------GGRTFECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQS 335
V ++M GG F+ L ++ Y+K +VE TLG L ++ +
Sbjct: 165 SKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVE--TLGTVL-----QLKQPLN 217
Query: 336 TTGAAAEKIYATLRE 350
TT A +I + +RE
Sbjct: 218 TTRINAAEIESRVRE 232
>BT007106-1|AAP35770.1| 460|Homo sapiens protein tyrosine
phosphatase, non-receptor type 11 (Noonan syndrome 1)
protein.
Length = 460
Score = 61.3 bits (142), Expect = 2e-08
Identities = 31/76 (40%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFHPN T EA ++L+ G GSFL RPS ++PGD++L N + +I+ G Y L
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDL 65
Query: 293 MGGRTFECLDAVINRY 308
GG F L ++ Y
Sbjct: 66 YGGEKFATLAELVQYY 81
Score = 55.2 bits (127), Expect = 1e-06
Identities = 34/91 (37%), Positives = 45/91 (49%), Gaps = 11/91 (12%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYL----------GRTG 110
P W+HG L +E+ L K GS+LVRES PG +VLS G++
Sbjct: 107 PTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSK 166
Query: 111 INHFRITAVCGDYYI-GGRQFDSLTELVGFY 140
+ H I Y + GG +FDSLT+LV Y
Sbjct: 167 VTHVMIRCQELKYDVGGGERFDSLTDLVEHY 197
Score = 52.4 bits (120), Expect = 7e-06
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 3/87 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H + +E L GS+L R S PG + LS + H +I GDYY
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNT-GDYYD 64
Query: 125 -IGGRQFDSLTELVGFYSHCSDLLKRE 150
GG +F +L ELV +Y LK +
Sbjct: 65 LYGGEKFATLAELVQYYMEHHGQLKEK 91
Score = 46.0 bits (104), Expect = 6e-04
Identities = 42/135 (31%), Positives = 62/135 (45%), Gaps = 20/135 (14%)
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK 286
DP T WFH + + EA +L + G GSFLVR S + PGD+ L + K
Sbjct: 106 DP-TSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGK 164
Query: 287 KGVRYLM-----------GGRTFECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQS 335
V ++M GG F+ L ++ Y+K +VE TLG L ++ +
Sbjct: 165 SKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVE--TLGTVL-----QLKQPLN 217
Query: 336 TTGAAAEKIYATLRE 350
TT A +I + +RE
Sbjct: 218 TTRINAAEIESRVRE 232
>BC008692-1|AAH08692.1| 460|Homo sapiens PTPN11 protein protein.
Length = 460
Score = 61.3 bits (142), Expect = 2e-08
Identities = 31/76 (40%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFHPN T EA ++L+ G GSFL RPS ++PGD++L N + +I+ G Y L
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDL 65
Query: 293 MGGRTFECLDAVINRY 308
GG F L ++ Y
Sbjct: 66 YGGEKFATLAELVQYY 81
Score = 55.2 bits (127), Expect = 1e-06
Identities = 34/91 (37%), Positives = 45/91 (49%), Gaps = 11/91 (12%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYL----------GRTG 110
P W+HG L +E+ L K GS+LVRES PG +VLS G++
Sbjct: 107 PTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSK 166
Query: 111 INHFRITAVCGDYYI-GGRQFDSLTELVGFY 140
+ H I Y + GG +FDSLT+LV Y
Sbjct: 167 VTHVMIRCQELKYDVGGGERFDSLTDLVEHY 197
Score = 52.4 bits (120), Expect = 7e-06
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 3/87 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H + +E L GS+L R S PG + LS + H +I GDYY
Sbjct: 6 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNT-GDYYD 64
Query: 125 -IGGRQFDSLTELVGFYSHCSDLLKRE 150
GG +F +L ELV +Y LK +
Sbjct: 65 LYGGEKFATLAELVQYYMEHHGQLKEK 91
Score = 46.0 bits (104), Expect = 6e-04
Identities = 42/135 (31%), Positives = 62/135 (45%), Gaps = 20/135 (14%)
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK 286
DP T WFH + + EA +L + G GSFLVR S + PGD+ L + K
Sbjct: 106 DP-TSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGK 164
Query: 287 KGVRYLM-----------GGRTFECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQS 335
V ++M GG F+ L ++ Y+K +VE TLG L ++ +
Sbjct: 165 SKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVE--TLGTVL-----QLKQPLN 217
Query: 336 TTGAAAEKIYATLRE 350
TT A +I + +RE
Sbjct: 218 TTRINAAEIESRVRE 232
>BC012924-1|AAH12924.1| 280|Homo sapiens DAPP1 protein protein.
Length = 280
Score = 60.1 bits (139), Expect = 4e-08
Identities = 57/234 (24%), Positives = 100/234 (42%), Gaps = 17/234 (7%)
Query: 235 WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLM 293
W+H N T+ A +L+ G GS+L+R S+ + G YSL + ++ F +E G +
Sbjct: 35 WYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKF 94
Query: 294 GGRTFECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQSTTGAAAEKIYATLRECRD 353
G F L + + + ++ G G ++ + + + + +++ ++ R
Sbjct: 95 GFNEFSSLKDFVKHFANQPLI-GSETGTLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRT 153
Query: 354 QIGLKKTK---GIKHYGYLNKKSDKGAKKWKPLYCVLLQEGTDTHLYFYDSPKRTKPKGL 410
+ L T G K GYL K+ K WK + L + L ++ +P +
Sbjct: 154 EDDLVPTAPSLGTKE-GYLTKQGGL-VKTWKTRWFTLHR----NELKYFKDQMSPEPIRI 207
Query: 411 IDLSCAYLYQVHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALR 464
+DL+ Q S E+ CF LV P + +L A T E WI+ LR
Sbjct: 208 LDLTECSAVQFDYS-QERVNCFCLV---FPFRT--FYLCAKTGVEADEWIKILR 255
Score = 55.6 bits (128), Expect = 8e-07
Identities = 25/77 (32%), Positives = 40/77 (51%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
WYHG L R+ +E L + GSYL+R+S+ G Y LS + + HF + +
Sbjct: 35 WYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKF 94
Query: 126 GGRQFDSLTELVGFYSH 142
G +F SL + V +++
Sbjct: 95 GFNEFSSLKDFVKHFAN 111
>AF186022-1|AAF14578.1| 280|Homo sapiens B lymphocyte adapter
protein BAM32 protein.
Length = 280
Score = 60.1 bits (139), Expect = 4e-08
Identities = 57/234 (24%), Positives = 100/234 (42%), Gaps = 17/234 (7%)
Query: 235 WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLM 293
W+H N T+ A +L+ G GS+L+R S+ + G YSL + ++ F +E G +
Sbjct: 35 WYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKF 94
Query: 294 GGRTFECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQSTTGAAAEKIYATLRECRD 353
G F L + + + ++ G G ++ + + + + +++ ++ R
Sbjct: 95 GFNEFSSLKDFVKHFANQPLI-GSETGTLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRT 153
Query: 354 QIGLKKTK---GIKHYGYLNKKSDKGAKKWKPLYCVLLQEGTDTHLYFYDSPKRTKPKGL 410
+ L T G K GYL K+ K WK + L + L ++ +P +
Sbjct: 154 EDDLVPTAPSLGTKE-GYLTKQGGL-VKTWKTRWFTLHR----NELKYFKDQMSPEPIRI 207
Query: 411 IDLSCAYLYQVHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALR 464
+DL+ Q S E+ CF LV P + +L A T E WI+ LR
Sbjct: 208 LDLTECSAVQFDYS-QERVNCFCLV---FPFRT--FYLCAKTGVEADEWIKILR 255
Score = 55.6 bits (128), Expect = 8e-07
Identities = 25/77 (32%), Positives = 40/77 (51%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
WYHG L R+ +E L + GSYL+R+S+ G Y LS + + HF + +
Sbjct: 35 WYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKF 94
Query: 126 GGRQFDSLTELVGFYSH 142
G +F SL + V +++
Sbjct: 95 GFNEFSSLKDFVKHFAN 111
>AF178987-1|AAF44351.1| 280|Homo sapiens protein-tyrosine
phosphatase D protein.
Length = 280
Score = 60.1 bits (139), Expect = 4e-08
Identities = 57/234 (24%), Positives = 100/234 (42%), Gaps = 17/234 (7%)
Query: 235 WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLM 293
W+H N T+ A +L+ G GS+L+R S+ + G YSL + ++ F +E G +
Sbjct: 35 WYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKF 94
Query: 294 GGRTFECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQSTTGAAAEKIYATLRECRD 353
G F L + + + ++ G G ++ + + + + +++ ++ R
Sbjct: 95 GFNEFSSLKDFVKHFANQPLI-GSETGTLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRT 153
Query: 354 QIGLKKTK---GIKHYGYLNKKSDKGAKKWKPLYCVLLQEGTDTHLYFYDSPKRTKPKGL 410
+ L T G K GYL K+ K WK + L + L ++ +P +
Sbjct: 154 EDDLVPTAPSLGTKE-GYLTKQGGL-VKTWKTRWFTLHR----NELKYFKDQMSPEPIRI 207
Query: 411 IDLSCAYLYQVHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALR 464
+DL+ Q S E+ CF LV P + +L A T E WI+ LR
Sbjct: 208 LDLTECSAVQFDYS-QERVNCFCLV---FPFRT--FYLCAKTGVEADEWIKILR 255
Score = 55.6 bits (128), Expect = 8e-07
Identities = 25/77 (32%), Positives = 40/77 (51%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
WYHG L R+ +E L + GSYL+R+S+ G Y LS + + HF + +
Sbjct: 35 WYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKF 94
Query: 126 GGRQFDSLTELVGFYSH 142
G +F SL + V +++
Sbjct: 95 GFNEFSSLKDFVKHFAN 111
>AF163254-1|AAD49697.1| 280|Homo sapiens adaptor protein DAPP1
protein.
Length = 280
Score = 60.1 bits (139), Expect = 4e-08
Identities = 57/234 (24%), Positives = 100/234 (42%), Gaps = 17/234 (7%)
Query: 235 WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLM 293
W+H N T+ A +L+ G GS+L+R S+ + G YSL + ++ F +E G +
Sbjct: 35 WYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKF 94
Query: 294 GGRTFECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQSTTGAAAEKIYATLRECRD 353
G F L + + + ++ G G ++ + + + + +++ ++ R
Sbjct: 95 GFNEFSSLKDFVKHFANQPLI-GSETGTLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRT 153
Query: 354 QIGLKKTK---GIKHYGYLNKKSDKGAKKWKPLYCVLLQEGTDTHLYFYDSPKRTKPKGL 410
+ L T G K GYL K+ K WK + L + L ++ +P +
Sbjct: 154 EDDLVPTAPSLGTKE-GYLTKQGGL-VKTWKTRWFTLHR----NELKYFKDQMSPEPIRI 207
Query: 411 IDLSCAYLYQVHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALR 464
+DL+ Q S E+ CF LV P + +L A T E WI+ LR
Sbjct: 208 LDLTECSAVQFDYS-QERVNCFCLV---FPFRT--FYLCAKTGVEADEWIKILR 255
Score = 55.6 bits (128), Expect = 8e-07
Identities = 25/77 (32%), Positives = 40/77 (51%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
WYHG L R+ +E L + GSYL+R+S+ G Y LS + + HF + +
Sbjct: 35 WYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKF 94
Query: 126 GGRQFDSLTELVGFYSH 142
G +F SL + V +++
Sbjct: 95 GFNEFSSLKDFVKHFAN 111
>Z82206-3|CAI42713.1| 330|Homo sapiens GRB2-related adaptor protein
2 protein.
Length = 330
Score = 59.3 bits (137), Expect = 6e-08
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 14/135 (10%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNC 240
DEL+F GD+ + ++ + W A ++G + + ++ P WFH
Sbjct: 15 DELSFHTGDVLKILSNQEE---WFKAELGSQEGYVPKNFIDIQFPK--------WFHEGL 63
Query: 241 TKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGGRTF 298
++ +A ++L+ G F++R S +SPGD+S+ + +Q F++ + KG Y + F
Sbjct: 64 SRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKG-NYFLWTEKF 122
Query: 299 ECLDAVINRYRKEQI 313
L+ +++ YR I
Sbjct: 123 PSLNKLVDYYRTNSI 137
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDY 123
+W+H L R+ +E L + G +++R S PG + +S + HF++ G+Y
Sbjct: 57 KWFHEGLSRHQAENLLMG-KEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115
Query: 124 YIGGRQFDSLTELVGFY 140
++ +F SL +LV +Y
Sbjct: 116 FLWTEKFPSLNKLVDYY 132
>Y18051-1|CAA77021.1| 330|Homo sapiens GADS protein protein.
Length = 330
Score = 59.3 bits (137), Expect = 6e-08
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 14/135 (10%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNC 240
DEL+F GD+ + ++ + W A ++G + + ++ P WFH
Sbjct: 15 DELSFHTGDVLKILSNQEE---WFKAELGSQEGYVPKNFIDIQFPK--------WFHEGL 63
Query: 241 TKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGGRTF 298
++ +A ++L+ G F++R S +SPGD+S+ + +Q F++ + KG Y + F
Sbjct: 64 SRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKG-NYFLWTEKF 122
Query: 299 ECLDAVINRYRKEQI 313
L+ +++ YR I
Sbjct: 123 PSLNKLVDYYRTNSI 137
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDY 123
+W+H L R+ +E L + G +++R S PG + +S + HF++ G+Y
Sbjct: 57 KWFHEGLSRHQAENLLMG-KEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115
Query: 124 YIGGRQFDSLTELVGFY 140
++ +F SL +LV +Y
Sbjct: 116 FLWTEKFPSLNKLVDYY 132
>CR541849-1|CAG46647.1| 330|Homo sapiens GRAP2 protein.
Length = 330
Score = 59.3 bits (137), Expect = 6e-08
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 14/135 (10%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNC 240
DEL+F GD+ + ++ + W A ++G + + ++ P WFH
Sbjct: 15 DELSFHTGDVLKILSNQEE---WFKAELGSQEGYVPKNFIDIQFPK--------WFHEGL 63
Query: 241 TKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGGRTF 298
++ +A ++L+ G F++R S +SPGD+S+ + +Q F++ + KG Y + F
Sbjct: 64 SRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKG-NYFLWTEKF 122
Query: 299 ECLDAVINRYRKEQI 313
L+ +++ YR I
Sbjct: 123 PSLNKLVDYYRTNSI 137
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDY 123
+W+H L R+ +E L + G +++R S PG + +S + HF++ G+Y
Sbjct: 57 KWFHEGLSRHQAENLLMG-KEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115
Query: 124 YIGGRQFDSLTELVGFY 140
++ +F SL +LV +Y
Sbjct: 116 FLWTEKFPSLNKLVDYY 132
>CR536524-1|CAG38761.1| 330|Homo sapiens GRAP2 protein.
Length = 330
Score = 59.3 bits (137), Expect = 6e-08
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 14/135 (10%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNC 240
DEL+F GD+ + ++ + W A ++G + + ++ P WFH
Sbjct: 15 DELSFHTGDVLKILSNQEE---WFKAELGSQEGYVPKNFIDIQFPK--------WFHEGL 63
Query: 241 TKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGGRTF 298
++ +A ++L+ G F++R S +SPGD+S+ + +Q F++ + KG Y + F
Sbjct: 64 SRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKG-NYFLWTEKF 122
Query: 299 ECLDAVINRYRKEQI 313
L+ +++ YR I
Sbjct: 123 PSLNKLVDYYRTNSI 137
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDY 123
+W+H L R+ +E L + G +++R S PG + +S + HF++ G+Y
Sbjct: 57 KWFHEGLSRHQAENLLMG-KEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115
Query: 124 YIGGRQFDSLTELVGFY 140
++ +F SL +LV +Y
Sbjct: 116 FLWTEKFPSLNKLVDYY 132
>CR456498-1|CAG30384.1| 330|Homo sapiens GRAP2 protein.
Length = 330
Score = 59.3 bits (137), Expect = 6e-08
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 14/135 (10%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNC 240
DEL+F GD+ + ++ + W A ++G + + ++ P WFH
Sbjct: 15 DELSFHTGDVLKILSNQEE---WFKAELGSQEGYVPKNFIDIQFPK--------WFHEGL 63
Query: 241 TKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGGRTF 298
++ +A ++L+ G F++R S +SPGD+S+ + +Q F++ + KG Y + F
Sbjct: 64 SRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKG-NYFLWTEKF 122
Query: 299 ECLDAVINRYRKEQI 313
L+ +++ YR I
Sbjct: 123 PSLNKLVDYYRTNSI 137
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDY 123
+W+H L R+ +E L + G +++R S PG + +S + HF++ G+Y
Sbjct: 57 KWFHEGLSRHQAENLLMG-KEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115
Query: 124 YIGGRQFDSLTELVGFY 140
++ +F SL +LV +Y
Sbjct: 116 FLWTEKFPSLNKLVDYY 132
>BC026002-1|AAH26002.1| 330|Homo sapiens GRAP2 protein protein.
Length = 330
Score = 59.3 bits (137), Expect = 6e-08
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 14/135 (10%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNC 240
DEL+F GD+ + ++ + W A ++G + + ++ P WFH
Sbjct: 15 DELSFHTGDVLKILSNQEE---WFKAELGSQEGYVPKNFIDIQFPK--------WFHEGL 63
Query: 241 TKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGGRTF 298
++ +A ++L+ G F++R S +SPGD+S+ + +Q F++ + KG Y + F
Sbjct: 64 SRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKG-NYFLWTEKF 122
Query: 299 ECLDAVINRYRKEQI 313
L+ +++ YR I
Sbjct: 123 PSLNKLVDYYRTNSI 137
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDY 123
+W+H L R+ +E L + G +++R S PG + +S + HF++ G+Y
Sbjct: 57 KWFHEGLSRHQAENLLMG-KEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115
Query: 124 YIGGRQFDSLTELVGFY 140
++ +F SL +LV +Y
Sbjct: 116 FLWTEKFPSLNKLVDYY 132
>BC025692-1|AAH25692.1| 330|Homo sapiens GRB2-related adaptor
protein 2 protein.
Length = 330
Score = 59.3 bits (137), Expect = 6e-08
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 14/135 (10%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNC 240
DEL+F GD+ + ++ + W A ++G + + ++ P WFH
Sbjct: 15 DELSFHTGDVLKILSNQEE---WFKAELGSQEGYVPKNFIDIQFPK--------WFHEGL 63
Query: 241 TKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGGRTF 298
++ +A ++L+ G F++R S +SPGD+S+ + +Q F++ + KG Y + F
Sbjct: 64 SRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKG-NYFLWTEKF 122
Query: 299 ECLDAVINRYRKEQI 313
L+ +++ YR I
Sbjct: 123 PSLNKLVDYYRTNSI 137
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDY 123
+W+H L R+ +E L + G +++R S PG + +S + HF++ G+Y
Sbjct: 57 KWFHEGLSRHQAENLLMG-KEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115
Query: 124 YIGGRQFDSLTELVGFY 140
++ +F SL +LV +Y
Sbjct: 116 FLWTEKFPSLNKLVDYY 132
>AY069959-1|AAL58573.1| 330|Homo sapiens Mona protein.
Length = 330
Score = 59.3 bits (137), Expect = 6e-08
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 14/135 (10%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNC 240
DEL+F GD+ + ++ + W A ++G + + ++ P WFH
Sbjct: 15 DELSFHTGDVLKILSNQEE---WFKAELGSQEGYVPKNFIDIQFPK--------WFHEGL 63
Query: 241 TKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGGRTF 298
++ +A ++L+ G F++R S +SPGD+S+ + +Q F++ + KG Y + F
Sbjct: 64 SRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKG-NYFLWTEKF 122
Query: 299 ECLDAVINRYRKEQI 313
L+ +++ YR I
Sbjct: 123 PSLNKLVDYYRTNSI 137
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDY 123
+W+H L R+ +E L + G +++R S PG + +S + HF++ G+Y
Sbjct: 57 KWFHEGLSRHQAENLLMG-KEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115
Query: 124 YIGGRQFDSLTELVGFY 140
++ +F SL +LV +Y
Sbjct: 116 FLWTEKFPSLNKLVDYY 132
>AJ011736-1|CAA09757.1| 330|Homo sapiens growth factor receptor
binding protein (GRBLG) protein.
Length = 330
Score = 59.3 bits (137), Expect = 6e-08
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 14/135 (10%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNC 240
DEL+F GD+ + ++ + W A ++G + + ++ P WFH
Sbjct: 15 DELSFHTGDVLKILSNQEE---WFKAELGSQEGYVPKNFIDIQFPK--------WFHEGL 63
Query: 241 TKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGGRTF 298
++ +A ++L+ G F++R S +SPGD+S+ + +Q F++ + KG Y + F
Sbjct: 64 SRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKG-NYFLWTEKF 122
Query: 299 ECLDAVINRYRKEQI 313
L+ +++ YR I
Sbjct: 123 PSLNKLVDYYRTNSI 137
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDY 123
+W+H L R+ +E L + G +++R S PG + +S + HF++ G+Y
Sbjct: 57 KWFHEGLSRHQAENLLMG-KEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115
Query: 124 YIGGRQFDSLTELVGFY 140
++ +F SL +LV +Y
Sbjct: 116 FLWTEKFPSLNKLVDYY 132
>AF236120-1|AAF60320.1| 330|Homo sapiens adapter protein GRID
protein.
Length = 330
Score = 59.3 bits (137), Expect = 6e-08
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 14/135 (10%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNC 240
DEL+F GD+ + ++ + W A ++G + + ++ P WFH
Sbjct: 15 DELSFHTGDVLKILSNQEE---WFKAELGSQEGYVPKNFIDIQFPK--------WFHEGL 63
Query: 241 TKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGGRTF 298
++ +A ++L+ G F++R S +SPGD+S+ + +Q F++ + KG Y + F
Sbjct: 64 SRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKG-NYFLWTEKF 122
Query: 299 ECLDAVINRYRKEQI 313
L+ +++ YR I
Sbjct: 123 PSLNKLVDYYRTNSI 137
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDY 123
+W+H L R+ +E L + G +++R S PG + +S + HF++ G+Y
Sbjct: 57 KWFHEGLSRHQAENLLMG-KEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115
Query: 124 YIGGRQFDSLTELVGFY 140
++ +F SL +LV +Y
Sbjct: 116 FLWTEKFPSLNKLVDYY 132
>AF236119-1|AAF60319.1| 330|Homo sapiens adapter protein GRID
protein.
Length = 330
Score = 59.3 bits (137), Expect = 6e-08
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 14/135 (10%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNC 240
DEL+F GD+ + ++ + W A ++G + + ++ P WFH
Sbjct: 15 DELSFHTGDVLKILSNQEE---WFKAELGSQEGYVPKNFIDIQFPK--------WFHEGL 63
Query: 241 TKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGGRTF 298
++ +A ++L+ G F++R S +SPGD+S+ + +Q F++ + KG Y + F
Sbjct: 64 SRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKG-NYFLWTEKF 122
Query: 299 ECLDAVINRYRKEQI 313
L+ +++ YR I
Sbjct: 123 PSLNKLVDYYRTNSI 137
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDY 123
+W+H L R+ +E L + G +++R S PG + +S + HF++ G+Y
Sbjct: 57 KWFHEGLSRHQAENLLMG-KEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115
Query: 124 YIGGRQFDSLTELVGFY 140
++ +F SL +LV +Y
Sbjct: 116 FLWTEKFPSLNKLVDYY 132
>AF129476-1|AAD41782.1| 330|Homo sapiens hematopoietic
cell-associated adaptor protein GrpL protein.
Length = 330
Score = 59.3 bits (137), Expect = 6e-08
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 14/135 (10%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNC 240
DEL+F GD+ + ++ + W A ++G + + ++ P WFH
Sbjct: 15 DELSFHTGDVLKILSNQEE---WFKAELGSQEGYVPKNFIDIQFPK--------WFHEGL 63
Query: 241 TKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGGRTF 298
++ +A ++L+ G F++R S +SPGD+S+ + +Q F++ + KG Y + F
Sbjct: 64 SRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKG-NYFLWTEKF 122
Query: 299 ECLDAVINRYRKEQI 313
L+ +++ YR I
Sbjct: 123 PSLNKLVDYYRTNSI 137
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDY 123
+W+H L R+ +E L + G +++R S PG + +S + HF++ G+Y
Sbjct: 57 KWFHEGLSRHQAENLLMG-KEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115
Query: 124 YIGGRQFDSLTELVGFY 140
++ +F SL +LV +Y
Sbjct: 116 FLWTEKFPSLNKLVDYY 132
>AF121002-1|AAF31758.1| 330|Homo sapiens SH3-SH2-SH3 adaptor
protein.
Length = 330
Score = 59.3 bits (137), Expect = 6e-08
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 14/135 (10%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNC 240
DEL+F GD+ + ++ + W A ++G + + ++ P WFH
Sbjct: 15 DELSFHTGDVLKILSNQEE---WFKAELGSQEGYVPKNFIDIQFPK--------WFHEGL 63
Query: 241 TKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGGRTF 298
++ +A ++L+ G F++R S +SPGD+S+ + +Q F++ + KG Y + F
Sbjct: 64 SRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKG-NYFLWTEKF 122
Query: 299 ECLDAVINRYRKEQI 313
L+ +++ YR I
Sbjct: 123 PSLNKLVDYYRTNSI 137
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDY 123
+W+H L R+ +E L + G +++R S PG + +S + HF++ G+Y
Sbjct: 57 KWFHEGLSRHQAENLLMG-KEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115
Query: 124 YIGGRQFDSLTELVGFY 140
++ +F SL +LV +Y
Sbjct: 116 FLWTEKFPSLNKLVDYY 132
>AF102694-1|AAD04926.1| 330|Homo sapiens Grb2-related adaptor
protein 2 protein.
Length = 330
Score = 59.3 bits (137), Expect = 6e-08
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 14/135 (10%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNC 240
DEL+F GD+ + ++ + W A ++G + + ++ P WFH
Sbjct: 15 DELSFHTGDVLKILSNQEE---WFKAELGSQEGYVPKNFIDIQFPK--------WFHEGL 63
Query: 241 TKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGGRTF 298
++ +A ++L+ G F++R S +SPGD+S+ + +Q F++ + KG Y + F
Sbjct: 64 SRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKG-NYFLWTEKF 122
Query: 299 ECLDAVINRYRKEQI 313
L+ +++ YR I
Sbjct: 123 PSLNKLVDYYRTNSI 137
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDY 123
+W+H L R+ +E L + G +++R S PG + +S + HF++ G+Y
Sbjct: 57 KWFHEGLSRHQAENLLMG-KEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115
Query: 124 YIGGRQFDSLTELVGFY 140
++ +F SL +LV +Y
Sbjct: 116 FLWTEKFPSLNKLVDYY 132
>AF090456-1|AAD13027.1| 330|Homo sapiens Grb-2-like protein
protein.
Length = 330
Score = 59.3 bits (137), Expect = 6e-08
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 14/135 (10%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNC 240
DEL+F GD+ + ++ + W A ++G + + ++ P WFH
Sbjct: 15 DELSFHTGDVLKILSNQEE---WFKAELGSQEGYVPKNFIDIQFPK--------WFHEGL 63
Query: 241 TKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGGRTF 298
++ +A ++L+ G F++R S +SPGD+S+ + +Q F++ + KG Y + F
Sbjct: 64 SRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKG-NYFLWTEKF 122
Query: 299 ECLDAVINRYRKEQI 313
L+ +++ YR I
Sbjct: 123 PSLNKLVDYYRTNSI 137
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDY 123
+W+H L R+ +E L + G +++R S PG + +S + HF++ G+Y
Sbjct: 57 KWFHEGLSRHQAENLLMG-KEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115
Query: 124 YIGGRQFDSLTELVGFY 140
++ +F SL +LV +Y
Sbjct: 116 FLWTEKFPSLNKLVDYY 132
>AF042380-1|AAC69273.1| 330|Homo sapiens Grf40 adaptor protein
protein.
Length = 330
Score = 59.3 bits (137), Expect = 6e-08
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 14/135 (10%)
Query: 181 DELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNC 240
DEL+F GD+ + ++ + W A ++G + + ++ P WFH
Sbjct: 15 DELSFHTGDVLKILSNQEE---WFKAELGSQEGYVPKNFIDIQFPK--------WFHEGL 63
Query: 241 TKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRI--EKKGVRYLMGGRTF 298
++ +A ++L+ G F++R S +SPGD+S+ + +Q F++ + KG Y + F
Sbjct: 64 SRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKG-NYFLWTEKF 122
Query: 299 ECLDAVINRYRKEQI 313
L+ +++ YR I
Sbjct: 123 PSLNKLVDYYRTNSI 137
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA-VCGDY 123
+W+H L R+ +E L + G +++R S PG + +S + HF++ G+Y
Sbjct: 57 KWFHEGLSRHQAENLLMG-KEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115
Query: 124 YIGGRQFDSLTELVGFY 140
++ +F SL +LV +Y
Sbjct: 116 FLWTEKFPSLNKLVDYY 132
>D78156-1|BAA11231.1| 410|Homo sapiens rasGTPase activating protein
protein.
Length = 410
Score = 58.4 bits (135), Expect = 1e-07
Identities = 32/109 (29%), Positives = 56/109 (51%)
Query: 723 KMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRT 782
K+ D+ NN E L +D++ +I S +CP + + L++ A ++PN+ V+
Sbjct: 2 KLKEGDNVENNKENLRYYVDKLFNTIVKSSMSCPTVMCDIFYSLRQMATQRFPNDPHVQY 61
Query: 783 RVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLAN 831
VS F+FLR A+V P + L P R+L +++K +Q L +
Sbjct: 62 SAVSSFVFLRFFAVAVVSPHTFHLRPHHPDAQTIRTLTLISKTIQTLGS 110
>J03358-1|AAA61190.1| 822|Homo sapiens FER protein.
Length = 822
Score = 57.6 bits (133), Expect = 2e-07
Identities = 31/75 (41%), Positives = 40/75 (53%), Gaps = 3/75 (4%)
Query: 63 ETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGD 122
E +WYHG + R ++E L KQG +LVRES KPG YVLS HF I V
Sbjct: 457 EQDWYHGAIPRIEAQELL---KKQGDFLVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNM 513
Query: 123 YYIGGRQFDSLTELV 137
Y G F ++ +L+
Sbjct: 514 YRFEGTGFSNIPQLI 528
Score = 41.5 bits (93), Expect = 0.013
Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 3/81 (3%)
Query: 235 WFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMG 294
W+H + EA ++L K G FLVR S PG+Y L + + Q + F I+ Y
Sbjct: 460 WYHGAIPRIEAQELLKKQG--DFLVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFE 517
Query: 295 GRTFECLDAVI-NRYRKEQIV 314
G F + +I + Y +Q++
Sbjct: 518 GTGFSNIPQLIDHHYTTKQVI 538
>M34667-1|AAA36452.1| 1290|Homo sapiens protein ( Human
phospholipase C-gamma mRNA, complete cds. ).
Length = 1290
Score = 57.2 bits (132), Expect = 3e-07
Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
EWYH L R +E L + G++LVR+ + +P SY +S+ I H R+
Sbjct: 667 EWYHASLTRAQAEHMLMRVPRDGAFLVRKRN-EPNSYAISFRAEGKIKHCRVQQEGQTVM 725
Query: 125 IGGRQFDSLTELVGFY 140
+G +FDSL +L+ +Y
Sbjct: 726 LGNSEFDSLVDLISYY 741
Score = 54.0 bits (124), Expect = 2e-06
Identities = 28/103 (27%), Positives = 53/103 (51%), Gaps = 2/103 (1%)
Query: 225 PSIDPNTVFSWFHPNCTKSEAVDMLVKA-GPGSFLVRPSDNSPGDYSLFFHINNQIQRFR 283
P + + W+H + T+++A ML++ G+FLVR N P Y++ F +I+ R
Sbjct: 658 PQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGKIKHCR 716
Query: 284 IEKKGVRYLMGGRTFECLDAVINRYRKEQIVEGHTLGQPLIAE 326
++++G ++G F+ L +I+ Y K + L P+ E
Sbjct: 717 VQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEE 759
Score = 35.5 bits (78), Expect = 0.88
Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 15/91 (16%)
Query: 65 EWYHGRL----------DRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHF 114
+W+HG+L +R +E + + GS+LVRES+ G Y LS+ + H
Sbjct: 549 KWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHC 608
Query: 115 RI----TAVCGDYYI-GGRQFDSLTELVGFY 140
RI A +++ FDSL +L+ Y
Sbjct: 609 RIHSRQDAGTPKFFLTDNLVFDSLYDLITHY 639
Score = 35.5 bits (78), Expect = 0.88
Identities = 17/36 (47%), Positives = 22/36 (61%)
Query: 252 AGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKK 287
A GSFLVR S+ GDY+L F N ++Q RI +
Sbjct: 578 APDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSR 613
>DQ297143-1|ABB84466.1| 1291|Homo sapiens phospholipase C, gamma 1
protein.
Length = 1291
Score = 57.2 bits (132), Expect = 3e-07
Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
EWYH L R +E L + G++LVR+ + +P SY +S+ I H R+
Sbjct: 667 EWYHASLTRAQAEHMLMRVPRDGAFLVRKRN-EPNSYAISFRAEGKIKHCRVQQEGQTVM 725
Query: 125 IGGRQFDSLTELVGFY 140
+G +FDSL +L+ +Y
Sbjct: 726 LGNSEFDSLVDLISYY 741
Score = 54.0 bits (124), Expect = 2e-06
Identities = 28/103 (27%), Positives = 53/103 (51%), Gaps = 2/103 (1%)
Query: 225 PSIDPNTVFSWFHPNCTKSEAVDMLVKA-GPGSFLVRPSDNSPGDYSLFFHINNQIQRFR 283
P + + W+H + T+++A ML++ G+FLVR N P Y++ F +I+ R
Sbjct: 658 PQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGKIKHCR 716
Query: 284 IEKKGVRYLMGGRTFECLDAVINRYRKEQIVEGHTLGQPLIAE 326
++++G ++G F+ L +I+ Y K + L P+ E
Sbjct: 717 VQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEE 759
Score = 35.5 bits (78), Expect = 0.88
Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 15/91 (16%)
Query: 65 EWYHGRL----------DRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHF 114
+W+HG+L +R +E + + GS+LVRES+ G Y LS+ + H
Sbjct: 549 KWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHC 608
Query: 115 RI----TAVCGDYYI-GGRQFDSLTELVGFY 140
RI A +++ FDSL +L+ Y
Sbjct: 609 RIHSRQDAGTPKFFLTDNLVFDSLYDLITHY 639
Score = 35.5 bits (78), Expect = 0.88
Identities = 17/36 (47%), Positives = 22/36 (61%)
Query: 252 AGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKK 287
A GSFLVR S+ GDY+L F N ++Q RI +
Sbjct: 578 APDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSR 613
>AL022394-3|CAA18537.1| 1290|Homo sapiens phospholipase C, gamma 1
protein.
Length = 1290
Score = 57.2 bits (132), Expect = 3e-07
Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
EWYH L R +E L + G++LVR+ + +P SY +S+ I H R+
Sbjct: 667 EWYHASLTRAQAEHMLMRVPRDGAFLVRKRN-EPNSYAISFRAEGKIKHCRVQQEGQTVM 725
Query: 125 IGGRQFDSLTELVGFY 140
+G +FDSL +L+ +Y
Sbjct: 726 LGNSEFDSLVDLISYY 741
Score = 54.0 bits (124), Expect = 2e-06
Identities = 28/103 (27%), Positives = 53/103 (51%), Gaps = 2/103 (1%)
Query: 225 PSIDPNTVFSWFHPNCTKSEAVDMLVKA-GPGSFLVRPSDNSPGDYSLFFHINNQIQRFR 283
P + + W+H + T+++A ML++ G+FLVR N P Y++ F +I+ R
Sbjct: 658 PQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGKIKHCR 716
Query: 284 IEKKGVRYLMGGRTFECLDAVINRYRKEQIVEGHTLGQPLIAE 326
++++G ++G F+ L +I+ Y K + L P+ E
Sbjct: 717 VQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEE 759
Score = 35.5 bits (78), Expect = 0.88
Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 15/91 (16%)
Query: 65 EWYHGRL----------DRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHF 114
+W+HG+L +R +E + + GS+LVRES+ G Y LS+ + H
Sbjct: 549 KWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHC 608
Query: 115 RI----TAVCGDYYI-GGRQFDSLTELVGFY 140
RI A +++ FDSL +L+ Y
Sbjct: 609 RIHSRQDAGTPKFFLTDNLVFDSLYDLITHY 639
Score = 35.5 bits (78), Expect = 0.88
Identities = 17/36 (47%), Positives = 22/36 (61%)
Query: 252 AGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKK 287
A GSFLVR S+ GDY+L F N ++Q RI +
Sbjct: 578 APDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSR 613
>AL022394-2|CAM28260.1| 1291|Homo sapiens phospholipase C, gamma 1
protein.
Length = 1291
Score = 57.2 bits (132), Expect = 3e-07
Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
EWYH L R +E L + G++LVR+ + +P SY +S+ I H R+
Sbjct: 667 EWYHASLTRAQAEHMLMRVPRDGAFLVRKRN-EPNSYAISFRAEGKIKHCRVQQEGQTVM 725
Query: 125 IGGRQFDSLTELVGFY 140
+G +FDSL +L+ +Y
Sbjct: 726 LGNSEFDSLVDLISYY 741
Score = 54.0 bits (124), Expect = 2e-06
Identities = 28/103 (27%), Positives = 53/103 (51%), Gaps = 2/103 (1%)
Query: 225 PSIDPNTVFSWFHPNCTKSEAVDMLVKA-GPGSFLVRPSDNSPGDYSLFFHINNQIQRFR 283
P + + W+H + T+++A ML++ G+FLVR N P Y++ F +I+ R
Sbjct: 658 PQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGKIKHCR 716
Query: 284 IEKKGVRYLMGGRTFECLDAVINRYRKEQIVEGHTLGQPLIAE 326
++++G ++G F+ L +I+ Y K + L P+ E
Sbjct: 717 VQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEE 759
Score = 35.5 bits (78), Expect = 0.88
Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 15/91 (16%)
Query: 65 EWYHGRL----------DRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHF 114
+W+HG+L +R +E + + GS+LVRES+ G Y LS+ + H
Sbjct: 549 KWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHC 608
Query: 115 RI----TAVCGDYYI-GGRQFDSLTELVGFY 140
RI A +++ FDSL +L+ Y
Sbjct: 609 RIHSRQDAGTPKFFLTDNLVFDSLYDLITHY 639
Score = 35.5 bits (78), Expect = 0.88
Identities = 17/36 (47%), Positives = 22/36 (61%)
Query: 252 AGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKK 287
A GSFLVR S+ GDY+L F N ++Q RI +
Sbjct: 578 APDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSR 613
>AB210028-1|BAE06110.1| 1412|Homo sapiens PLCG1 variant protein
protein.
Length = 1412
Score = 57.2 bits (132), Expect = 3e-07
Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
EWYH L R +E L + G++LVR+ + +P SY +S+ I H R+
Sbjct: 789 EWYHASLTRAQAEHMLMRVPRDGAFLVRKRN-EPNSYAISFRAEGKIKHCRVQQEGQTVM 847
Query: 125 IGGRQFDSLTELVGFY 140
+G +FDSL +L+ +Y
Sbjct: 848 LGNSEFDSLVDLISYY 863
Score = 54.0 bits (124), Expect = 2e-06
Identities = 28/103 (27%), Positives = 53/103 (51%), Gaps = 2/103 (1%)
Query: 225 PSIDPNTVFSWFHPNCTKSEAVDMLVKA-GPGSFLVRPSDNSPGDYSLFFHINNQIQRFR 283
P + + W+H + T+++A ML++ G+FLVR N P Y++ F +I+ R
Sbjct: 780 PQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGKIKHCR 838
Query: 284 IEKKGVRYLMGGRTFECLDAVINRYRKEQIVEGHTLGQPLIAE 326
++++G ++G F+ L +I+ Y K + L P+ E
Sbjct: 839 VQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEE 881
Score = 35.5 bits (78), Expect = 0.88
Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 15/91 (16%)
Query: 65 EWYHGRL----------DRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHF 114
+W+HG+L +R +E + + GS+LVRES+ G Y LS+ + H
Sbjct: 671 KWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHC 730
Query: 115 RI----TAVCGDYYI-GGRQFDSLTELVGFY 140
RI A +++ FDSL +L+ Y
Sbjct: 731 RIHSRQDAGTPKFFLTDNLVFDSLYDLITHY 761
Score = 35.5 bits (78), Expect = 0.88
Identities = 17/36 (47%), Positives = 22/36 (61%)
Query: 252 AGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKK 287
A GSFLVR S+ GDY+L F N ++Q RI +
Sbjct: 700 APDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSR 735
>X59656-1|CAA42199.1| 303|Homo sapiens CRKL protein.
Length = 303
Score = 56.8 bits (131), Expect = 3e-07
Identities = 48/170 (28%), Positives = 75/170 (44%), Gaps = 14/170 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCG-DYY 124
WY G + R ++ RL + G +LVR+S PG YVLS + ++H+ I ++ +
Sbjct: 14 WYMGPVSRQEAQTRL-QGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFK 72
Query: 125 IGGRQFDSLTELVGFYS-HCSD----LLKRERLXXXXXXXXXXNDKKRVVAILPYTK--- 176
IG ++FD L L+ FY H D + R + L Y +
Sbjct: 73 IGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYVRTLY 132
Query: 177 -MP--DTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDL 223
P D ++L F+KG+I + + W W ++ G GMI VE L
Sbjct: 133 DFPGNDAEDLPFKKGEILVIIEKPEEQW-WSARNKDGRVGMIPVPYVEKL 181
Score = 41.1 bits (92), Expect = 0.018
Identities = 27/90 (30%), Positives = 44/90 (48%), Gaps = 2/90 (2%)
Query: 234 SWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK-KGVRYL 292
+W+ ++ EA L G FLVR S PGDY L N+++ + I R+
Sbjct: 13 AWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFK 72
Query: 293 MGGRTFECLDAVINRYRKEQIVEGHTLGQP 322
+G + F+ L A++ Y K ++ TL +P
Sbjct: 73 IGDQEFDHLPALLEFY-KIHYLDTTTLIEP 101
>K03218-1|AAA60584.1| 536|Homo sapiens SRC protein.
Length = 536
Score = 56.8 bits (131), Expect = 3e-07
Identities = 36/89 (40%), Positives = 54/89 (60%), Gaps = 8/89 (8%)
Query: 65 EWYHGRLDRYTSEERLW-AASKQGSYLVRESDRKPGSYVLS---YLGRTGIN--HFRITA 118
EWY G++ R SE L A + +G++LVRES+ G+Y LS + G+N H++I
Sbjct: 150 EWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRK 209
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSD 145
+ G +YI R QF+SL +LV +YS +D
Sbjct: 210 LDSGGFYITSRTQFNSLQQLVAYYSKHAD 238
Score = 47.6 bits (108), Expect = 2e-04
Identities = 47/152 (30%), Positives = 72/152 (47%), Gaps = 16/152 (10%)
Query: 169 VAILPYTKMPDTDELTFQKGD-IFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
VA+ Y +TD L+F+KG+ + V+N GD WL + TG+ G I V D SI
Sbjct: 90 VALYDYESRTETD-LSFKKGERLQIVNNTEGDWWL-AHSLSTGQTGYIPSNYVAPSD-SI 146
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKA-GP-GSFLVRPSDNSPGDYSL-FFHINN----QIQ 280
W+ T+ E+ +L+ A P G+FLVR S+ + G Y L +N ++
Sbjct: 147 QAE---EWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVK 203
Query: 281 RFRIEK--KGVRYLMGGRTFECLDAVINRYRK 310
++I K G Y+ F L ++ Y K
Sbjct: 204 HYKIRKLDSGGFYITSRTQFNSLQQLVAYYSK 235
>CR456423-1|CAG30309.1| 303|Homo sapiens CRKL protein.
Length = 303
Score = 56.8 bits (131), Expect = 3e-07
Identities = 48/170 (28%), Positives = 75/170 (44%), Gaps = 14/170 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCG-DYY 124
WY G + R ++ RL + G +LVR+S PG YVLS + ++H+ I ++ +
Sbjct: 14 WYMGPVSRQEAQTRL-QGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFK 72
Query: 125 IGGRQFDSLTELVGFYS-HCSD----LLKRERLXXXXXXXXXXNDKKRVVAILPYTK--- 176
IG ++FD L L+ FY H D + R + L Y +
Sbjct: 73 IGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYVRTLY 132
Query: 177 -MP--DTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDL 223
P D ++L F+KG+I + + W W ++ G GMI VE L
Sbjct: 133 DFPGNDAEDLPFKKGEILVIIEKPEEQW-WSARNKDGRVGMIPVPYVEKL 181
Score = 41.1 bits (92), Expect = 0.018
Identities = 27/90 (30%), Positives = 44/90 (48%), Gaps = 2/90 (2%)
Query: 234 SWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK-KGVRYL 292
+W+ ++ EA L G FLVR S PGDY L N+++ + I R+
Sbjct: 13 AWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFK 72
Query: 293 MGGRTFECLDAVINRYRKEQIVEGHTLGQP 322
+G + F+ L A++ Y K ++ TL +P
Sbjct: 73 IGDQEFDHLPALLEFY-KIHYLDTTTLIEP 101
>BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogene homolog (avian)
protein.
Length = 536
Score = 56.8 bits (131), Expect = 3e-07
Identities = 36/89 (40%), Positives = 54/89 (60%), Gaps = 8/89 (8%)
Query: 65 EWYHGRLDRYTSEERLW-AASKQGSYLVRESDRKPGSYVLS---YLGRTGIN--HFRITA 118
EWY G++ R SE L A + +G++LVRES+ G+Y LS + G+N H++I
Sbjct: 150 EWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRK 209
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSD 145
+ G +YI R QF+SL +LV +YS +D
Sbjct: 210 LDSGGFYITSRTQFNSLQQLVAYYSKHAD 238
Score = 47.6 bits (108), Expect = 2e-04
Identities = 47/152 (30%), Positives = 72/152 (47%), Gaps = 16/152 (10%)
Query: 169 VAILPYTKMPDTDELTFQKGD-IFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
VA+ Y +TD L+F+KG+ + V+N GD WL + TG+ G I V D SI
Sbjct: 90 VALYDYESRTETD-LSFKKGERLQIVNNTEGDWWL-AHSLSTGQTGYIPSNYVAPSD-SI 146
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKA-GP-GSFLVRPSDNSPGDYSL-FFHINN----QIQ 280
W+ T+ E+ +L+ A P G+FLVR S+ + G Y L +N ++
Sbjct: 147 QAE---EWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVK 203
Query: 281 RFRIEK--KGVRYLMGGRTFECLDAVINRYRK 310
++I K G Y+ F L ++ Y K
Sbjct: 204 HYKIRKLDSGGFYITSRTQFNSLQQLVAYYSK 235
>BC043500-1|AAH43500.1| 303|Homo sapiens v-crk sarcoma virus CT10
oncogene homolog (avian)-like protein.
Length = 303
Score = 56.8 bits (131), Expect = 3e-07
Identities = 48/170 (28%), Positives = 75/170 (44%), Gaps = 14/170 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCG-DYY 124
WY G + R ++ RL + G +LVR+S PG YVLS + ++H+ I ++ +
Sbjct: 14 WYMGPVSRQEAQTRL-QGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFK 72
Query: 125 IGGRQFDSLTELVGFYS-HCSD----LLKRERLXXXXXXXXXXNDKKRVVAILPYTK--- 176
IG ++FD L L+ FY H D + R + L Y +
Sbjct: 73 IGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYVRTLY 132
Query: 177 -MP--DTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDL 223
P D ++L F+KG+I + + W W ++ G GMI VE L
Sbjct: 133 DFPGNDAEDLPFKKGEILVIIEKPEEQW-WSARNKDGRVGMIPVPYVEKL 181
Score = 41.1 bits (92), Expect = 0.018
Identities = 27/90 (30%), Positives = 44/90 (48%), Gaps = 2/90 (2%)
Query: 234 SWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK-KGVRYL 292
+W+ ++ EA L G FLVR S PGDY L N+++ + I R+
Sbjct: 13 AWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFK 72
Query: 293 MGGRTFECLDAVINRYRKEQIVEGHTLGQP 322
+G + F+ L A++ Y K ++ TL +P
Sbjct: 73 IGDQEFDHLPALLEFY-KIHYLDTTTLIEP 101
>BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein.
Length = 536
Score = 56.8 bits (131), Expect = 3e-07
Identities = 36/89 (40%), Positives = 54/89 (60%), Gaps = 8/89 (8%)
Query: 65 EWYHGRLDRYTSEERLW-AASKQGSYLVRESDRKPGSYVLS---YLGRTGIN--HFRITA 118
EWY G++ R SE L A + +G++LVRES+ G+Y LS + G+N H++I
Sbjct: 150 EWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRK 209
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSD 145
+ G +YI R QF+SL +LV +YS +D
Sbjct: 210 LDSGGFYITSRTQFNSLQQLVAYYSKHAD 238
Score = 47.6 bits (108), Expect = 2e-04
Identities = 47/152 (30%), Positives = 72/152 (47%), Gaps = 16/152 (10%)
Query: 169 VAILPYTKMPDTDELTFQKGD-IFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
VA+ Y +TD L+F+KG+ + V+N GD WL + TG+ G I V D SI
Sbjct: 90 VALYDYESRTETD-LSFKKGERLQIVNNTEGDWWL-AHSLSTGQTGYIPSNYVAPSD-SI 146
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKA-GP-GSFLVRPSDNSPGDYSL-FFHINN----QIQ 280
W+ T+ E+ +L+ A P G+FLVR S+ + G Y L +N ++
Sbjct: 147 QAE---EWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVK 203
Query: 281 RFRIEK--KGVRYLMGGRTFECLDAVINRYRK 310
++I K G Y+ F L ++ Y K
Sbjct: 204 HYKIRKLDSGGFYITSRTQFNSLQQLVAYYSK 235
>AL133293-2|CAC10573.1| 542|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogenem exchanger), member
2 protein.
Length = 542
Score = 56.8 bits (131), Expect = 3e-07
Identities = 36/89 (40%), Positives = 54/89 (60%), Gaps = 8/89 (8%)
Query: 65 EWYHGRLDRYTSEERLW-AASKQGSYLVRESDRKPGSYVLS---YLGRTGIN--HFRITA 118
EWY G++ R SE L A + +G++LVRES+ G+Y LS + G+N H++I
Sbjct: 156 EWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRK 215
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSD 145
+ G +YI R QF+SL +LV +YS +D
Sbjct: 216 LDSGGFYITSRTQFNSLQQLVAYYSKHAD 244
Score = 40.7 bits (91), Expect = 0.023
Identities = 48/158 (30%), Positives = 75/158 (47%), Gaps = 22/158 (13%)
Query: 169 VAILPYTKMPDTDELTFQKGD-IFFVHN----DMGDGWLWVTAHR--TGEQGMIFRELVE 221
VA+ Y +TD L+F+KG+ + V+N D+ +G W+ AH TG+ G I V
Sbjct: 90 VALYDYESRTETD-LSFKKGERLQIVNNTRKVDVREGDWWL-AHSLSTGQTGYIPSNYVA 147
Query: 222 DLDPSIDPNTVFSWFHPNCTKSEAVDMLVKA-GP-GSFLVRPSDNSPGDYSL-FFHINN- 277
D SI W+ T+ E+ +L+ A P G+FLVR S+ + G Y L +N
Sbjct: 148 PSD-SIQAE---EWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNA 203
Query: 278 ---QIQRFRIEK--KGVRYLMGGRTFECLDAVINRYRK 310
++ ++I K G Y+ F L ++ Y K
Sbjct: 204 KGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSK 241
>AL133293-1|CAC34523.1| 536|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogenem exchanger), member
2 protein.
Length = 536
Score = 56.8 bits (131), Expect = 3e-07
Identities = 36/89 (40%), Positives = 54/89 (60%), Gaps = 8/89 (8%)
Query: 65 EWYHGRLDRYTSEERLW-AASKQGSYLVRESDRKPGSYVLS---YLGRTGIN--HFRITA 118
EWY G++ R SE L A + +G++LVRES+ G+Y LS + G+N H++I
Sbjct: 150 EWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRK 209
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSD 145
+ G +YI R QF+SL +LV +YS +D
Sbjct: 210 LDSGGFYITSRTQFNSLQQLVAYYSKHAD 238
Score = 47.6 bits (108), Expect = 2e-04
Identities = 47/152 (30%), Positives = 72/152 (47%), Gaps = 16/152 (10%)
Query: 169 VAILPYTKMPDTDELTFQKGD-IFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
VA+ Y +TD L+F+KG+ + V+N GD WL + TG+ G I V D SI
Sbjct: 90 VALYDYESRTETD-LSFKKGERLQIVNNTEGDWWL-AHSLSTGQTGYIPSNYVAPSD-SI 146
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKA-GP-GSFLVRPSDNSPGDYSL-FFHINN----QIQ 280
W+ T+ E+ +L+ A P G+FLVR S+ + G Y L +N ++
Sbjct: 147 QAE---EWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVK 203
Query: 281 RFRIEK--KGVRYLMGGRTFECLDAVINRYRK 310
++I K G Y+ F L ++ Y K
Sbjct: 204 HYKIRKLDSGGFYITSRTQFNSLQQLVAYYSK 235
>X17576-1|CAA35599.1| 377|Homo sapiens protein ( Human melanoma
mRNA for nck protein, showing homology to src. ).
Length = 377
Score = 55.6 bits (128), Expect = 8e-07
Identities = 44/168 (26%), Positives = 78/168 (46%), Gaps = 23/168 (13%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIF-FVHNDMGDGWLWVTAHRTGEQGMIFRE-------- 218
V A+ P++ D +EL F+KGD+ + D W G G++ +
Sbjct: 195 VQALYPFSSSND-EELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVPKNYVTVMQNN 253
Query: 219 -LVEDLDPS------IDPNTV--FS---WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNS 265
L L+PS I P+ F+ W++ T+ +A L + G G FL+R S++S
Sbjct: 254 PLTSGLEPSPPQCDYIRPSLTGKFAGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESS 313
Query: 266 PGDYSLFFHINNQIQRFRIEKKGVRYLMGGRTFECLDAVINRYRKEQI 313
P D+S+ + + F+++ K Y +G R F ++ ++ Y+K I
Sbjct: 314 PNDFSVSLKAQGKNKHFKVQLKETVYCIGQRKFSTMEELVEHYKKAPI 361
Score = 51.6 bits (118), Expect = 1e-05
Identities = 23/75 (30%), Positives = 41/75 (54%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
WY+G++ R+ +E L +G +L+R+S+ P + +S + HF++ Y I
Sbjct: 282 WYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYCI 341
Query: 126 GGRQFDSLTELVGFY 140
G R+F ++ ELV Y
Sbjct: 342 GQRKFSTMEELVEHY 356
>BC006403-1|AAH06403.1| 377|Homo sapiens NCK adaptor protein 1
protein.
Length = 377
Score = 55.6 bits (128), Expect = 8e-07
Identities = 44/168 (26%), Positives = 78/168 (46%), Gaps = 23/168 (13%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIF-FVHNDMGDGWLWVTAHRTGEQGMIFRE-------- 218
V A+ P++ D +EL F+KGD+ + D W G G++ +
Sbjct: 195 VQALYPFSSSND-EELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVPKNYVTVMQNN 253
Query: 219 -LVEDLDPS------IDPNTV--FS---WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNS 265
L L+PS I P+ F+ W++ T+ +A L + G G FL+R S++S
Sbjct: 254 PLTSGLEPSPPQCDYIRPSLTGKFAGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESS 313
Query: 266 PGDYSLFFHINNQIQRFRIEKKGVRYLMGGRTFECLDAVINRYRKEQI 313
P D+S+ + + F+++ K Y +G R F ++ ++ Y+K I
Sbjct: 314 PNDFSVSLKAQGKNKHFKVQLKETVYCIGQRKFSTMEELVEHYKKAPI 361
Score = 51.6 bits (118), Expect = 1e-05
Identities = 23/75 (30%), Positives = 41/75 (54%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
WY+G++ R+ +E L +G +L+R+S+ P + +S + HF++ Y I
Sbjct: 282 WYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYCI 341
Query: 126 GGRQFDSLTELVGFY 140
G R+F ++ ELV Y
Sbjct: 342 GQRKFSTMEELVEHY 356
>X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase
protein.
Length = 450
Score = 54.4 bits (125), Expect = 2e-06
Identities = 40/150 (26%), Positives = 67/150 (44%), Gaps = 5/150 (3%)
Query: 182 ELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFS---WFHP 238
+L F KGD+ + D + ++ G +G+I V+ + + T S WFH
Sbjct: 27 DLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKRE-GVKAGTKLSLMPWFHG 85
Query: 239 NCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGGRT- 297
T+ +A +L G FLVR S N PGDY+L + +++ +RI + +
Sbjct: 86 KITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSIDEEVY 145
Query: 298 FECLDAVINRYRKEQIVEGHTLGQPLIAEG 327
FE L ++ Y + L +P + EG
Sbjct: 146 FENLMQLVEHYTSDADGLCTRLIKPKVMEG 175
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
W+HG++ R +E RL + G +LVRES PG Y L + H+RI I
Sbjct: 82 WFHGKITREQAE-RLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSI 140
Query: 126 GGR-QFDSLTELVGFYSHCSD 145
F++L +LV Y+ +D
Sbjct: 141 DEEVYFENLMQLVEHYTSDAD 161
>X62055-1|CAA43982.1| 597|Homo sapiens protein-tyrosine
phosphatase 1C protein.
Length = 597
Score = 54.4 bits (125), Expect = 2e-06
Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFH + + +A +L G GSFL RPS + GD+SL + +Q+ RI+ G Y L
Sbjct: 6 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDL 65
Query: 293 MGGRTFECLDAVINRYRKEQ 312
GG F L ++ Y ++Q
Sbjct: 66 YGGEKFATLTELVEYYTQQQ 85
Score = 53.2 bits (122), Expect = 4e-06
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 10/87 (11%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLG---RTG------I 111
P WYHG + +E L A + ++LVRES +PG +VLS L + G +
Sbjct: 107 PTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRV 166
Query: 112 NHFRITAVCGDYYIGGRQ-FDSLTELV 137
H ++ G Y +GG + FDSLT+LV
Sbjct: 167 THIKVMCEGGRYTVGGLETFDSLTDLV 193
Score = 48.8 bits (111), Expect = 9e-05
Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H L +E L GS+L R S + G + LS + H RI GD+Y
Sbjct: 6 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQN-SGDFYD 64
Query: 125 -IGGRQFDSLTELVGFYSHCSDLLK 148
GG +F +LTELV +Y+ +L+
Sbjct: 65 LYGGEKFATLTELVEYYTQQQGVLQ 89
Score = 39.1 bits (87), Expect = 0.072
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 12/99 (12%)
Query: 228 DPNTVFSWFHPNCTKSEAVDML-VKAGPGSFLVRPSDNSPGDYSLFFHINN--------- 277
DP T W+H + + +A +L K P +FLVR S + PGD+ L +
Sbjct: 106 DP-TSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 164
Query: 278 QIQRFRIEKKGVRYLMGG-RTFECLDAVINRYRKEQIVE 315
++ ++ +G RY +GG TF+ L ++ ++K I E
Sbjct: 165 RVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEE 203
>X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine
kinase protein.
Length = 450
Score = 54.4 bits (125), Expect = 2e-06
Identities = 40/150 (26%), Positives = 67/150 (44%), Gaps = 5/150 (3%)
Query: 182 ELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFS---WFHP 238
+L F KGD+ + D + ++ G +G+I V+ + + T S WFH
Sbjct: 27 DLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKRE-GVKAGTKLSLMPWFHG 85
Query: 239 NCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGGRT- 297
T+ +A +L G FLVR S N PGDY+L + +++ +RI + +
Sbjct: 86 KITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSIDEEVY 145
Query: 298 FECLDAVINRYRKEQIVEGHTLGQPLIAEG 327
FE L ++ Y + L +P + EG
Sbjct: 146 FENLMQLVEHYTSDADGLCTRLIKPKVMEG 175
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
W+HG++ R +E RL + G +LVRES PG Y L + H+RI I
Sbjct: 82 WFHGKITREQAE-RLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSI 140
Query: 126 GGR-QFDSLTELVGFYSHCSD 145
F++L +LV Y+ +D
Sbjct: 141 DEEVYFENLMQLVEHYTSDAD 161
>X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein.
Length = 450
Score = 54.4 bits (125), Expect = 2e-06
Identities = 40/150 (26%), Positives = 67/150 (44%), Gaps = 5/150 (3%)
Query: 182 ELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFS---WFHP 238
+L F KGD+ + D + ++ G +G+I V+ + + T S WFH
Sbjct: 27 DLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKRE-GVKAGTKLSLMPWFHG 85
Query: 239 NCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGGRT- 297
T+ +A +L G FLVR S N PGDY+L + +++ +RI + +
Sbjct: 86 KITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSIDEEVY 145
Query: 298 FECLDAVINRYRKEQIVEGHTLGQPLIAEG 327
FE L ++ Y + L +P + EG
Sbjct: 146 FENLMQLVEHYTSDADGLCTRLIKPKVMEG 175
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
W+HG++ R +E RL + G +LVRES PG Y L + H+RI I
Sbjct: 82 WFHGKITREQAE-RLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSI 140
Query: 126 GGR-QFDSLTELVGFYSHCSD 145
F++L +LV Y+ +D
Sbjct: 141 DEEVYFENLMQLVEHYTSDAD 161
>X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyrosine
kinase protein.
Length = 659
Score = 54.4 bits (125), Expect = 2e-06
Identities = 32/110 (29%), Positives = 61/110 (55%), Gaps = 7/110 (6%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVED 222
++ K+VVA+ Y M + ++L +KGD +F+ + W W + G++G I V +
Sbjct: 214 SELKKVVALYDYMPM-NANDLQLRKGDEYFILEESNLPW-WRARDKNGQEGYIPSNYVTE 271
Query: 223 LDPSIDPNTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSL 271
+ SI+ ++ W+ + T+S+A +L + G G F+VR S + G Y++
Sbjct: 272 AEDSIE---MYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKA-GKYTV 317
Score = 41.9 bits (94), Expect = 0.010
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 9/88 (10%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGR-TG-----INHFRITA 118
EWY + R +E+ L K+G ++VR+S K G Y +S + TG I H+ + +
Sbjct: 280 EWYSKHMTRSQAEQLLKQEGKEGGFIVRDSS-KAGKYTVSVFAKSTGDPQGVIRHYVVCS 338
Query: 119 V-CGDYYIGGRQ-FDSLTELVGFYSHCS 144
YY+ + F ++ EL+ ++ H S
Sbjct: 339 TPQSQYYLAEKHLFSTIPELINYHQHNS 366
>U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 659
Score = 54.4 bits (125), Expect = 2e-06
Identities = 32/110 (29%), Positives = 61/110 (55%), Gaps = 7/110 (6%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVED 222
++ K+VVA+ Y M + ++L +KGD +F+ + W W + G++G I V +
Sbjct: 214 SELKKVVALYDYMPM-NANDLQLRKGDEYFILEESNLPW-WRARDKNGQEGYIPSNYVTE 271
Query: 223 LDPSIDPNTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSL 271
+ SI+ ++ W+ + T+S+A +L + G G F+VR S + G Y++
Sbjct: 272 AEDSIE---MYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKA-GKYTV 317
Score = 41.9 bits (94), Expect = 0.010
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 9/88 (10%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGR-TG-----INHFRITA 118
EWY + R +E+ L K+G ++VR+S K G Y +S + TG I H+ + +
Sbjct: 280 EWYSKHMTRSQAEQLLKQEGKEGGFIVRDSS-KAGKYTVSVFAKSTGDPQGVIRHYVVCS 338
Query: 119 V-CGDYYIGGRQ-FDSLTELVGFYSHCS 144
YY+ + F ++ EL+ ++ H S
Sbjct: 339 TPQSQYYLAEKHLFSTIPELINYHQHNS 366
>U47924-18|AAB51323.1| 595|Homo sapiens protein tyrosine
phosphatase 1C protein.
Length = 595
Score = 54.4 bits (125), Expect = 2e-06
Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFH + + +A +L G GSFL RPS + GD+SL + +Q+ RI+ G Y L
Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDL 63
Query: 293 MGGRTFECLDAVINRYRKEQ 312
GG F L ++ Y ++Q
Sbjct: 64 YGGEKFATLTELVEYYTQQQ 83
Score = 53.2 bits (122), Expect = 4e-06
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 10/87 (11%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLG---RTG------I 111
P WYHG + +E L A + ++LVRES +PG +VLS L + G +
Sbjct: 105 PTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRV 164
Query: 112 NHFRITAVCGDYYIGGRQ-FDSLTELV 137
H ++ G Y +GG + FDSLT+LV
Sbjct: 165 THIKVMCEGGRYTVGGLETFDSLTDLV 191
Score = 48.8 bits (111), Expect = 9e-05
Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H L +E L GS+L R S + G + LS + H RI GD+Y
Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQN-SGDFYD 62
Query: 125 -IGGRQFDSLTELVGFYSHCSDLLK 148
GG +F +LTELV +Y+ +L+
Sbjct: 63 LYGGEKFATLTELVEYYTQQQGVLQ 87
Score = 39.1 bits (87), Expect = 0.072
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 12/99 (12%)
Query: 228 DPNTVFSWFHPNCTKSEAVDML-VKAGPGSFLVRPSDNSPGDYSLFFHINN--------- 277
DP T W+H + + +A +L K P +FLVR S + PGD+ L +
Sbjct: 104 DP-TSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 162
Query: 278 QIQRFRIEKKGVRYLMGG-RTFECLDAVINRYRKEQIVE 315
++ ++ +G RY +GG TF+ L ++ ++K I E
Sbjct: 163 RVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEE 201
>U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 54.4 bits (125), Expect = 2e-06
Identities = 32/110 (29%), Positives = 61/110 (55%), Gaps = 7/110 (6%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVED 222
++ K+VVA+ Y M + ++L +KGD +F+ + W W + G++G I V +
Sbjct: 214 SELKKVVALYDYMPM-NANDLQLRKGDEYFILEESNLPW-WRARDKNGQEGYIPSNYVTE 271
Query: 223 LDPSIDPNTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSL 271
+ SI+ ++ W+ + T+S+A +L + G G F+VR S + G Y++
Sbjct: 272 AEDSIE---MYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKA-GKYTV 317
Score = 41.9 bits (94), Expect = 0.010
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 9/88 (10%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGR-TG-----INHFRITA 118
EWY + R +E+ L K+G ++VR+S K G Y +S + TG I H+ + +
Sbjct: 280 EWYSKHMTRSQAEQLLKQEGKEGGFIVRDSS-KAGKYTVSVFAKSTGDPQGVIRHYVVCS 338
Query: 119 V-CGDYYIGGRQ-FDSLTELVGFYSHCS 144
YY+ + F ++ EL+ ++ H S
Sbjct: 339 TPQSQYYLAEKHLFSTIPELINYHQHNS 366
>M77273-1|AAA36610.1| 595|Homo sapiens tyrosine phosphatase
protein.
Length = 595
Score = 54.4 bits (125), Expect = 2e-06
Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFH + + +A +L G GSFL RPS + GD+SL + +Q+ RI+ G Y L
Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDL 63
Query: 293 MGGRTFECLDAVINRYRKEQ 312
GG F L ++ Y ++Q
Sbjct: 64 YGGEKFATLTELVEYYTQQQ 83
Score = 53.2 bits (122), Expect = 4e-06
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 10/87 (11%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLG---RTG------I 111
P WYHG + +E L A + ++LVRES +PG +VLS L + G +
Sbjct: 105 PTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRV 164
Query: 112 NHFRITAVCGDYYIGGRQ-FDSLTELV 137
H ++ G Y +GG + FDSLT+LV
Sbjct: 165 THIKVMCEGGRYTVGGLETFDSLTDLV 191
Score = 48.0 bits (109), Expect = 2e-04
Identities = 28/78 (35%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H L +E L GS+L R S + G + LS + H RI GD+Y
Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQN-SGDFYD 62
Query: 125 -IGGRQFDSLTELVGFYS 141
GG +F +LTELV +Y+
Sbjct: 63 LYGGEKFATLTELVEYYT 80
Score = 39.1 bits (87), Expect = 0.072
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 12/99 (12%)
Query: 228 DPNTVFSWFHPNCTKSEAVDML-VKAGPGSFLVRPSDNSPGDYSLFFHINN--------- 277
DP T W+H + + +A +L K P +FLVR S + PGD+ L +
Sbjct: 104 DP-TSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 162
Query: 278 QIQRFRIEKKGVRYLMGG-RTFECLDAVINRYRKEQIVE 315
++ ++ +G RY +GG TF+ L ++ ++K I E
Sbjct: 163 RVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEE 201
>M74903-1|AAA35963.1| 595|Homo sapiens hematopoietic cell
phophatase protein.
Length = 595
Score = 54.4 bits (125), Expect = 2e-06
Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFH + + +A +L G GSFL RPS + GD+SL + +Q+ RI+ G Y L
Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDL 63
Query: 293 MGGRTFECLDAVINRYRKEQ 312
GG F L ++ Y ++Q
Sbjct: 64 YGGEKFATLTELVEYYTQQQ 83
Score = 53.2 bits (122), Expect = 4e-06
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 10/87 (11%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLG---RTG------I 111
P WYHG + +E L A + ++LVRES +PG +VLS L + G +
Sbjct: 105 PTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRV 164
Query: 112 NHFRITAVCGDYYIGGRQ-FDSLTELV 137
H ++ G Y +GG + FDSLT+LV
Sbjct: 165 THIKVMCEGGRYTVGGLETFDSLTDLV 191
Score = 48.8 bits (111), Expect = 9e-05
Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H L +E L GS+L R S + G + LS + H RI GD+Y
Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQN-SGDFYD 62
Query: 125 -IGGRQFDSLTELVGFYSHCSDLLK 148
GG +F +LTELV +Y+ +L+
Sbjct: 63 LYGGEKFATLTELVEYYTQQQGVLQ 87
Score = 39.1 bits (87), Expect = 0.072
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 12/99 (12%)
Query: 228 DPNTVFSWFHPNCTKSEAVDML-VKAGPGSFLVRPSDNSPGDYSLFFHINN--------- 277
DP T W+H + + +A +L K P +FLVR S + PGD+ L +
Sbjct: 104 DP-TSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 162
Query: 278 QIQRFRIEKKGVRYLMGG-RTFECLDAVINRYRKEQIVE 315
++ ++ +G RY +GG TF+ L ++ ++K I E
Sbjct: 163 RVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEE 201
>L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia
protein.
Length = 659
Score = 54.4 bits (125), Expect = 2e-06
Identities = 32/110 (29%), Positives = 61/110 (55%), Gaps = 7/110 (6%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVED 222
++ K+VVA+ Y M + ++L +KGD +F+ + W W + G++G I V +
Sbjct: 214 SELKKVVALYDYMPM-NANDLQLRKGDEYFILEESNLPW-WRARDKNGQEGYIPSNYVTE 271
Query: 223 LDPSIDPNTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSL 271
+ SI+ ++ W+ + T+S+A +L + G G F+VR S + G Y++
Sbjct: 272 AEDSIE---MYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKA-GKYTV 317
Score = 41.9 bits (94), Expect = 0.010
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 9/88 (10%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGR-TG-----INHFRITA 118
EWY + R +E+ L K+G ++VR+S K G Y +S + TG I H+ + +
Sbjct: 280 EWYSKHMTRSQAEQLLKQEGKEGGFIVRDSS-KAGKYTVSVFAKSTGDPQGVIRHYVVCS 338
Query: 119 V-CGDYYIGGRQ-FDSLTELVGFYSHCS 144
YY+ + F ++ EL+ ++ H S
Sbjct: 339 TPQSQYYLAEKHLFSTIPELINYHQHNS 366
>DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 54.4 bits (125), Expect = 2e-06
Identities = 40/150 (26%), Positives = 67/150 (44%), Gaps = 5/150 (3%)
Query: 182 ELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFS---WFHP 238
+L F KGD+ + D + ++ G +G+I V+ + + T S WFH
Sbjct: 27 DLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKRE-GVKAGTKLSLMPWFHG 85
Query: 239 NCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGGRT- 297
T+ +A +L G FLVR S N PGDY+L + +++ +RI + +
Sbjct: 86 KITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSIDEEVY 145
Query: 298 FECLDAVINRYRKEQIVEGHTLGQPLIAEG 327
FE L ++ Y + L +P + EG
Sbjct: 146 FENLMQLVEHYTSDADGLCTRLIKPKVMEG 175
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
W+HG++ R +E RL + G +LVRES PG Y L + H+RI I
Sbjct: 82 WFHGKITREQAE-RLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSI 140
Query: 126 GGR-QFDSLTELVGFYSHCSD 145
F++L +LV Y+ +D
Sbjct: 141 DEEVYFENLMQLVEHYTSDAD 161
>CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein.
Length = 450
Score = 54.4 bits (125), Expect = 2e-06
Identities = 40/150 (26%), Positives = 67/150 (44%), Gaps = 5/150 (3%)
Query: 182 ELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFS---WFHP 238
+L F KGD+ + D + ++ G +G+I V+ + + T S WFH
Sbjct: 27 DLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKRE-GVKAGTKLSLMPWFHG 85
Query: 239 NCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGGRT- 297
T+ +A +L G FLVR S N PGDY+L + +++ +RI + +
Sbjct: 86 KITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSIDEEVY 145
Query: 298 FECLDAVINRYRKEQIVEGHTLGQPLIAEG 327
FE L ++ Y + L +P + EG
Sbjct: 146 FENLMQLVEHYTSDADGLCTRLIKPKVMEG 175
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
W+HG++ R +E RL + G +LVRES PG Y L + H+RI I
Sbjct: 82 WFHGKITREQAE-RLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSI 140
Query: 126 GGR-QFDSLTELVGFYSHCSD 145
F++L +LV Y+ +D
Sbjct: 141 DEEVYFENLMQLVEHYTSDAD 161
>BT007390-1|AAP36054.1| 597|Homo sapiens protein tyrosine
phosphatase, non-receptor type 6 protein.
Length = 597
Score = 54.4 bits (125), Expect = 2e-06
Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFH + + +A +L G GSFL RPS + GD+SL + +Q+ RI+ G Y L
Sbjct: 6 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDL 65
Query: 293 MGGRTFECLDAVINRYRKEQ 312
GG F L ++ Y ++Q
Sbjct: 66 YGGEKFATLTELVEYYTQQQ 85
Score = 53.2 bits (122), Expect = 4e-06
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 10/87 (11%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLG---RTG------I 111
P WYHG + +E L A + ++LVRES +PG +VLS L + G +
Sbjct: 107 PTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRV 166
Query: 112 NHFRITAVCGDYYIGGRQ-FDSLTELV 137
H ++ G Y +GG + FDSLT+LV
Sbjct: 167 THIKVMCEGGRYTVGGLETFDSLTDLV 193
Score = 48.8 bits (111), Expect = 9e-05
Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H L +E L GS+L R S + G + LS + H RI GD+Y
Sbjct: 6 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQN-SGDFYD 64
Query: 125 -IGGRQFDSLTELVGFYSHCSDLLK 148
GG +F +LTELV +Y+ +L+
Sbjct: 65 LYGGEKFATLTELVEYYTQQQGVLQ 89
Score = 39.1 bits (87), Expect = 0.072
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 12/99 (12%)
Query: 228 DPNTVFSWFHPNCTKSEAVDML-VKAGPGSFLVRPSDNSPGDYSLFFHINN--------- 277
DP T W+H + + +A +L K P +FLVR S + PGD+ L +
Sbjct: 106 DP-TSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 164
Query: 278 QIQRFRIEKKGVRYLMGG-RTFECLDAVINRYRKEQIVE 315
++ ++ +G RY +GG TF+ L ++ ++K I E
Sbjct: 165 RVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEE 203
>BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 54.4 bits (125), Expect = 2e-06
Identities = 32/110 (29%), Positives = 61/110 (55%), Gaps = 7/110 (6%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVED 222
++ K+VVA+ Y M + ++L +KGD +F+ + W W + G++G I V +
Sbjct: 214 SELKKVVALYDYMPM-NANDLQLRKGDEYFILEESNLPW-WRARDKNGQEGYIPSNYVTE 271
Query: 223 LDPSIDPNTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSL 271
+ SI+ ++ W+ + T+S+A +L + G G F+VR S + G Y++
Sbjct: 272 AEDSIE---MYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKA-GKYTV 317
Score = 41.9 bits (94), Expect = 0.010
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 9/88 (10%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGR-TG-----INHFRITA 118
EWY + R +E+ L K+G ++VR+S K G Y +S + TG I H+ + +
Sbjct: 280 EWYSKHMTRSQAEQLLKQEGKEGGFIVRDSS-KAGKYTVSVFAKSTGDPQGVIRHYVVCS 338
Query: 119 V-CGDYYIGGRQ-FDSLTELVGFYSHCS 144
YY+ + F ++ EL+ ++ H S
Sbjct: 339 TPQSQYYLAEKHLFSTIPELINYHQHNS 366
>BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 54.4 bits (125), Expect = 2e-06
Identities = 32/110 (29%), Positives = 61/110 (55%), Gaps = 7/110 (6%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVED 222
++ K+VVA+ Y M + ++L +KGD +F+ + W W + G++G I V +
Sbjct: 214 SELKKVVALYDYMPM-NANDLQLRKGDEYFILEESNLPW-WRARDKNGQEGYIPSNYVTE 271
Query: 223 LDPSIDPNTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSL 271
+ SI+ ++ W+ + T+S+A +L + G G F+VR S + G Y++
Sbjct: 272 AEDSIE---MYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKA-GKYTV 317
Score = 41.9 bits (94), Expect = 0.010
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 9/88 (10%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGR-TG-----INHFRITA 118
EWY + R +E+ L K+G ++VR+S K G Y +S + TG I H+ + +
Sbjct: 280 EWYSKHMTRSQAEQLLKQEGKEGGFIVRDSS-KAGKYTVSVFAKSTGDPQGVIRHYVVCS 338
Query: 119 V-CGDYYIGGRQ-FDSLTELVGFYSHCS 144
YY+ + F ++ EL+ ++ H S
Sbjct: 339 TPQSQYYLAEKHLFSTIPELINYHQHNS 366
>BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 54.4 bits (125), Expect = 2e-06
Identities = 40/150 (26%), Positives = 67/150 (44%), Gaps = 5/150 (3%)
Query: 182 ELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFS---WFHP 238
+L F KGD+ + D + ++ G +G+I V+ + + T S WFH
Sbjct: 27 DLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKRE-GVKAGTKLSLMPWFHG 85
Query: 239 NCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGGRT- 297
T+ +A +L G FLVR S N PGDY+L + +++ +RI + +
Sbjct: 86 KITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSIDEEVY 145
Query: 298 FECLDAVINRYRKEQIVEGHTLGQPLIAEG 327
FE L ++ Y + L +P + EG
Sbjct: 146 FENLMQLVEHYTSDADGLCTRLIKPKVMEG 175
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
W+HG++ R +E RL + G +LVRES PG Y L + H+RI I
Sbjct: 82 WFHGKITREQAE-RLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSI 140
Query: 126 GGR-QFDSLTELVGFYSHCSD 145
F++L +LV Y+ +D
Sbjct: 141 DEEVYFENLMQLVEHYTSDAD 161
>BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 54.4 bits (125), Expect = 2e-06
Identities = 40/150 (26%), Positives = 67/150 (44%), Gaps = 5/150 (3%)
Query: 182 ELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFS---WFHP 238
+L F KGD+ + D + ++ G +G+I V+ + + T S WFH
Sbjct: 27 DLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKRE-GVKAGTKLSLMPWFHG 85
Query: 239 NCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGGRT- 297
T+ +A +L G FLVR S N PGDY+L + +++ +RI + +
Sbjct: 86 KITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSIDEEVY 145
Query: 298 FECLDAVINRYRKEQIVEGHTLGQPLIAEG 327
FE L ++ Y + L +P + EG
Sbjct: 146 FENLMQLVEHYTSDADGLCTRLIKPKVMEG 175
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
W+HG++ R +E RL + G +LVRES PG Y L + H+RI I
Sbjct: 82 WFHGKITREQAE-RLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSI 140
Query: 126 GGR-QFDSLTELVGFYSHCSD 145
F++L +LV Y+ +D
Sbjct: 141 DEEVYFENLMQLVEHYTSDAD 161
>BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 54.4 bits (125), Expect = 2e-06
Identities = 40/150 (26%), Positives = 67/150 (44%), Gaps = 5/150 (3%)
Query: 182 ELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFS---WFHP 238
+L F KGD+ + D + ++ G +G+I V+ + + T S WFH
Sbjct: 27 DLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKRE-GVKAGTKLSLMPWFHG 85
Query: 239 NCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGGRT- 297
T+ +A +L G FLVR S N PGDY+L + +++ +RI + +
Sbjct: 86 KITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSIDEEVY 145
Query: 298 FECLDAVINRYRKEQIVEGHTLGQPLIAEG 327
FE L ++ Y + L +P + EG
Sbjct: 146 FENLMQLVEHYTSDADGLCTRLIKPKVMEG 175
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
W+HG++ R +E RL + G +LVRES PG Y L + H+RI I
Sbjct: 82 WFHGKITREQAE-RLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSI 140
Query: 126 GGR-QFDSLTELVGFYSHCSD 145
F++L +LV Y+ +D
Sbjct: 141 DEEVYFENLMQLVEHYTSDAD 161
>BC007667-1|AAH07667.1| 597|Homo sapiens protein tyrosine
phosphatase, non-receptor type 6 protein.
Length = 597
Score = 54.4 bits (125), Expect = 2e-06
Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFH + + +A +L G GSFL RPS + GD+SL + +Q+ RI+ G Y L
Sbjct: 6 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDL 65
Query: 293 MGGRTFECLDAVINRYRKEQ 312
GG F L ++ Y ++Q
Sbjct: 66 YGGEKFATLTELVEYYTQQQ 85
Score = 53.2 bits (122), Expect = 4e-06
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 10/87 (11%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLG---RTG------I 111
P WYHG + +E L A + ++LVRES +PG +VLS L + G +
Sbjct: 107 PTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRV 166
Query: 112 NHFRITAVCGDYYIGGRQ-FDSLTELV 137
H ++ G Y +GG + FDSLT+LV
Sbjct: 167 THIKVMCEGGRYTVGGLETFDSLTDLV 193
Score = 48.8 bits (111), Expect = 9e-05
Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H L +E L GS+L R S + G + LS + H RI GD+Y
Sbjct: 6 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQN-SGDFYD 64
Query: 125 -IGGRQFDSLTELVGFYSHCSDLLK 148
GG +F +LTELV +Y+ +L+
Sbjct: 65 LYGGEKFATLTELVEYYTQQQGVLQ 89
Score = 39.1 bits (87), Expect = 0.072
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 12/99 (12%)
Query: 228 DPNTVFSWFHPNCTKSEAVDML-VKAGPGSFLVRPSDNSPGDYSLFFHINN--------- 277
DP T W+H + + +A +L K P +FLVR S + PGD+ L +
Sbjct: 106 DP-TSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 164
Query: 278 QIQRFRIEKKGVRYLMGG-RTFECLDAVINRYRKEQIVE 315
++ ++ +G RY +GG TF+ L ++ ++K I E
Sbjct: 165 RVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEE 203
>BC002523-1|AAH02523.1| 597|Homo sapiens protein tyrosine
phosphatase, non-receptor type 6 protein.
Length = 597
Score = 54.4 bits (125), Expect = 2e-06
Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFH + + +A +L G GSFL RPS + GD+SL + +Q+ RI+ G Y L
Sbjct: 6 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDL 65
Query: 293 MGGRTFECLDAVINRYRKEQ 312
GG F L ++ Y ++Q
Sbjct: 66 YGGEKFATLTELVEYYTQQQ 85
Score = 53.2 bits (122), Expect = 4e-06
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 10/87 (11%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLG---RTG------I 111
P WYHG + +E L A + ++LVRES +PG +VLS L + G +
Sbjct: 107 PTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRV 166
Query: 112 NHFRITAVCGDYYIGGRQ-FDSLTELV 137
H ++ G Y +GG + FDSLT+LV
Sbjct: 167 THIKVMCEGGRYTVGGLETFDSLTDLV 193
Score = 48.8 bits (111), Expect = 9e-05
Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H L +E L GS+L R S + G + LS + H RI GD+Y
Sbjct: 6 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQN-SGDFYD 64
Query: 125 -IGGRQFDSLTELVGFYSHCSDLLK 148
GG +F +LTELV +Y+ +L+
Sbjct: 65 LYGGEKFATLTELVEYYTQQQGVLQ 89
Score = 39.1 bits (87), Expect = 0.072
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 12/99 (12%)
Query: 228 DPNTVFSWFHPNCTKSEAVDML-VKAGPGSFLVRPSDNSPGDYSLFFHINN--------- 277
DP T W+H + + +A +L K P +FLVR S + PGD+ L +
Sbjct: 106 DP-TSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 164
Query: 278 QIQRFRIEKKGVRYLMGG-RTFECLDAVINRYRKEQIVE 315
++ ++ +G RY +GG TF+ L ++ ++K I E
Sbjct: 165 RVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEE 203
>AL035422-4|CAI42359.1| 483|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 483
Score = 54.4 bits (125), Expect = 2e-06
Identities = 32/110 (29%), Positives = 61/110 (55%), Gaps = 7/110 (6%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVED 222
++ K+VVA+ Y M + ++L +KGD +F+ + W W + G++G I V +
Sbjct: 214 SELKKVVALYDYMPM-NANDLQLRKGDEYFILEESNLPW-WRARDKNGQEGYIPSNYVTE 271
Query: 223 LDPSIDPNTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSL 271
+ SI+ ++ W+ + T+S+A +L + G G F+VR S + G Y++
Sbjct: 272 AEDSIE---MYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKA-GKYTV 317
Score = 34.7 bits (76), Expect = 1.5
Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 8/71 (11%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGR-TG-----INHFRITA 118
EWY + R +E+ L K+G ++VR+S K G Y +S + TG I H+ + +
Sbjct: 280 EWYSKHMTRSQAEQLLKQEGKEGGFIVRDSS-KAGKYTVSVFAKSTGDPQGVIRHYVVCS 338
Query: 119 V-CGDYYIGGR 128
YY+ R
Sbjct: 339 TPQSQYYLAAR 349
>AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 54.4 bits (125), Expect = 2e-06
Identities = 32/110 (29%), Positives = 61/110 (55%), Gaps = 7/110 (6%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVED 222
++ K+VVA+ Y M + ++L +KGD +F+ + W W + G++G I V +
Sbjct: 214 SELKKVVALYDYMPM-NANDLQLRKGDEYFILEESNLPW-WRARDKNGQEGYIPSNYVTE 271
Query: 223 LDPSIDPNTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSL 271
+ SI+ ++ W+ + T+S+A +L + G G F+VR S + G Y++
Sbjct: 272 AEDSIE---MYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKA-GKYTV 317
Score = 41.9 bits (94), Expect = 0.010
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 9/88 (10%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGR-TG-----INHFRITA 118
EWY + R +E+ L K+G ++VR+S K G Y +S + TG I H+ + +
Sbjct: 280 EWYSKHMTRSQAEQLLKQEGKEGGFIVRDSS-KAGKYTVSVFAKSTGDPQGVIRHYVVCS 338
Query: 119 V-CGDYYIGGRQ-FDSLTELVGFYSHCS 144
YY+ + F ++ EL+ ++ H S
Sbjct: 339 TPQSQYYLAEKHLFSTIPELINYHQHNS 366
>AK223629-1|BAD97349.1| 595|Homo sapiens protein tyrosine
phosphatase, non-receptor type 6 isoform 1 variant
protein.
Length = 595
Score = 54.4 bits (125), Expect = 2e-06
Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFH + + +A +L G GSFL RPS + GD+SL + +Q+ RI+ G Y L
Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDL 63
Query: 293 MGGRTFECLDAVINRYRKEQ 312
GG F L ++ Y ++Q
Sbjct: 64 YGGEKFATLTELVEYYTQQQ 83
Score = 53.2 bits (122), Expect = 4e-06
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 10/87 (11%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLG---RTG------I 111
P WYHG + +E L A + ++LVRES +PG +VLS L + G +
Sbjct: 105 PTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRV 164
Query: 112 NHFRITAVCGDYYIGGRQ-FDSLTELV 137
H ++ G Y +GG + FDSLT+LV
Sbjct: 165 THIKVMCEGGRYTVGGLETFDSLTDLV 191
Score = 48.8 bits (111), Expect = 9e-05
Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H L +E L GS+L R S + G + LS + H RI GD+Y
Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQN-SGDFYD 62
Query: 125 -IGGRQFDSLTELVGFYSHCSDLLK 148
GG +F +LTELV +Y+ +L+
Sbjct: 63 LYGGEKFATLTELVEYYTQQQGVLQ 87
Score = 39.1 bits (87), Expect = 0.072
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 12/99 (12%)
Query: 228 DPNTVFSWFHPNCTKSEAVDML-VKAGPGSFLVRPSDNSPGDYSLFFHINN--------- 277
DP T W+H + + +A +L K P +FLVR S + PGD+ L +
Sbjct: 104 DP-TSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 162
Query: 278 QIQRFRIEKKGVRYLMGG-RTFECLDAVINRYRKEQIVE 315
++ ++ +G RY +GG TF+ L ++ ++K I E
Sbjct: 163 RVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEE 201
>AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase
variant protein.
Length = 449
Score = 54.4 bits (125), Expect = 2e-06
Identities = 40/150 (26%), Positives = 67/150 (44%), Gaps = 5/150 (3%)
Query: 182 ELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFS---WFHP 238
+L F KGD+ + D + ++ G +G+I V+ + + T S WFH
Sbjct: 27 DLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKRE-GVKAGTKLSLMPWFHG 85
Query: 239 NCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGGRT- 297
T+ +A +L G FLVR S N PGDY+L + +++ +RI + +
Sbjct: 86 KITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSIDEEVY 145
Query: 298 FECLDAVINRYRKEQIVEGHTLGQPLIAEG 327
FE L ++ Y + L +P + EG
Sbjct: 146 FENLMQLVEHYTSDADGLCTRLIKPKVMEG 175
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYI 125
W+HG++ R +E RL + G +LVRES PG Y L + H+RI I
Sbjct: 82 WFHGKITREQAE-RLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHASKLSI 140
Query: 126 GGR-QFDSLTELVGFYSHCSD 145
F++L +LV Y+ +D
Sbjct: 141 DEEVYFENLMQLVEHYTSDAD 161
>AF178946-1|AAD53317.1| 624|Homo sapiens 70 kDa SHP-1L protein
protein.
Length = 624
Score = 54.4 bits (125), Expect = 2e-06
Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFH + + +A +L G GSFL RPS + GD+SL + +Q+ RI+ G Y L
Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDL 63
Query: 293 MGGRTFECLDAVINRYRKEQ 312
GG F L ++ Y ++Q
Sbjct: 64 YGGEKFATLTELVEYYTQQQ 83
Score = 53.2 bits (122), Expect = 4e-06
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 10/87 (11%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLG---RTG------I 111
P WYHG + +E L A + ++LVRES +PG +VLS L + G +
Sbjct: 105 PTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRV 164
Query: 112 NHFRITAVCGDYYIGGRQ-FDSLTELV 137
H ++ G Y +GG + FDSLT+LV
Sbjct: 165 THIKVMCEGGRYTVGGLETFDSLTDLV 191
Score = 48.0 bits (109), Expect = 2e-04
Identities = 28/78 (35%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H L +E L GS+L R S + G + LS + H RI GD+Y
Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQN-SGDFYD 62
Query: 125 -IGGRQFDSLTELVGFYS 141
GG +F +LTELV +Y+
Sbjct: 63 LYGGEKFATLTELVEYYT 80
Score = 39.1 bits (87), Expect = 0.072
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 12/99 (12%)
Query: 228 DPNTVFSWFHPNCTKSEAVDML-VKAGPGSFLVRPSDNSPGDYSLFFHINN--------- 277
DP T W+H + + +A +L K P +FLVR S + PGD+ L +
Sbjct: 104 DP-TSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 162
Query: 278 QIQRFRIEKKGVRYLMGG-RTFECLDAVINRYRKEQIVE 315
++ ++ +G RY +GG TF+ L ++ ++K I E
Sbjct: 163 RVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEE 201
>AB079851-2|BAC81775.1| 595|Homo sapiens protein tyrosine
phosphatase SHP-1 protein.
Length = 595
Score = 54.4 bits (125), Expect = 2e-06
Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFH + + +A +L G GSFL RPS + GD+SL + +Q+ RI+ G Y L
Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDL 63
Query: 293 MGGRTFECLDAVINRYRKEQ 312
GG F L ++ Y ++Q
Sbjct: 64 YGGEKFATLTELVEYYTQQQ 83
Score = 53.2 bits (122), Expect = 4e-06
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 10/87 (11%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLG---RTG------I 111
P WYHG + +E L A + ++LVRES +PG +VLS L + G +
Sbjct: 105 PTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRV 164
Query: 112 NHFRITAVCGDYYIGGRQ-FDSLTELV 137
H ++ G Y +GG + FDSLT+LV
Sbjct: 165 THIKVMCEGGRYTVGGLETFDSLTDLV 191
Score = 48.8 bits (111), Expect = 9e-05
Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H L +E L GS+L R S + G + LS + H RI GD+Y
Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQN-SGDFYD 62
Query: 125 -IGGRQFDSLTELVGFYSHCSDLLK 148
GG +F +LTELV +Y+ +L+
Sbjct: 63 LYGGEKFATLTELVEYYTQQQGVLQ 87
Score = 39.1 bits (87), Expect = 0.072
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 12/99 (12%)
Query: 228 DPNTVFSWFHPNCTKSEAVDML-VKAGPGSFLVRPSDNSPGDYSLFFHINN--------- 277
DP T W+H + + +A +L K P +FLVR S + PGD+ L +
Sbjct: 104 DP-TSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 162
Query: 278 QIQRFRIEKKGVRYLMGG-RTFECLDAVINRYRKEQIVE 315
++ ++ +G RY +GG TF+ L ++ ++K I E
Sbjct: 163 RVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEE 201
>AB079851-1|BAC81774.1| 597|Homo sapiens protein tyrosine
phosphatase SHP-1 protein.
Length = 597
Score = 54.4 bits (125), Expect = 2e-06
Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WFH + + +A +L G GSFL RPS + GD+SL + +Q+ RI+ G Y L
Sbjct: 6 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDL 65
Query: 293 MGGRTFECLDAVINRYRKEQ 312
GG F L ++ Y ++Q
Sbjct: 66 YGGEKFATLTELVEYYTQQQ 85
Score = 53.2 bits (122), Expect = 4e-06
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 10/87 (11%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLG---RTG------I 111
P WYHG + +E L A + ++LVRES +PG +VLS L + G +
Sbjct: 107 PTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRV 166
Query: 112 NHFRITAVCGDYYIGGRQ-FDSLTELV 137
H ++ G Y +GG + FDSLT+LV
Sbjct: 167 THIKVMCEGGRYTVGGLETFDSLTDLV 193
Score = 48.8 bits (111), Expect = 9e-05
Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+H L +E L GS+L R S + G + LS + H RI GD+Y
Sbjct: 6 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQN-SGDFYD 64
Query: 125 -IGGRQFDSLTELVGFYSHCSDLLK 148
GG +F +LTELV +Y+ +L+
Sbjct: 65 LYGGEKFATLTELVEYYTQQQGVLQ 89
Score = 39.1 bits (87), Expect = 0.072
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 12/99 (12%)
Query: 228 DPNTVFSWFHPNCTKSEAVDML-VKAGPGSFLVRPSDNSPGDYSLFFHINN--------- 277
DP T W+H + + +A +L K P +FLVR S + PGD+ L +
Sbjct: 106 DP-TSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 164
Query: 278 QIQRFRIEKKGVRYLMGG-RTFECLDAVINRYRKEQIVE 315
++ ++ +G RY +GG TF+ L ++ ++K I E
Sbjct: 165 RVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEE 203
>BC007195-1|AAH07195.1| 380|Homo sapiens NCK adaptor protein 2
protein.
Length = 380
Score = 54.0 bits (124), Expect = 2e-06
Identities = 39/166 (23%), Positives = 77/166 (46%), Gaps = 21/166 (12%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIF-FVHNDMGDGWLWVTAHRTGEQGMIFRELV------ 220
V + P++ + + +EL F+KG+ + D W + G+ G++ + V
Sbjct: 200 VQTLYPFSSVTE-EELNFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYVVVLSDG 258
Query: 221 EDLDPSIDPNTVFS------------WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPG 267
L P+ P ++ W++ N T+ +A L + G G FL+R S++SP
Sbjct: 259 PALHPAHAPQISYTGPSSSGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPS 318
Query: 268 DYSLFFHINNQIQRFRIEKKGVRYLMGGRTFECLDAVINRYRKEQI 313
D+S+ + + + F+++ Y +G R F +D ++ Y+K I
Sbjct: 319 DFSVSLKASGKNKHFKVQLVDNVYCIGQRRFHTMDELVEHYKKAPI 364
Score = 54.0 bits (124), Expect = 2e-06
Identities = 25/76 (32%), Positives = 41/76 (53%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
EWY+G + R+ +E L +G +L+R+S+ P + +S HF++ V Y
Sbjct: 284 EWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVYC 343
Query: 125 IGGRQFDSLTELVGFY 140
IG R+F ++ ELV Y
Sbjct: 344 IGQRRFHTMDELVEHY 359
>BC000103-1|AAH00103.1| 380|Homo sapiens NCK adaptor protein 2
protein.
Length = 380
Score = 54.0 bits (124), Expect = 2e-06
Identities = 39/166 (23%), Positives = 77/166 (46%), Gaps = 21/166 (12%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIF-FVHNDMGDGWLWVTAHRTGEQGMIFRELV------ 220
V + P++ + + +EL F+KG+ + D W + G+ G++ + V
Sbjct: 200 VQTLYPFSSVTE-EELNFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYVVVLSDG 258
Query: 221 EDLDPSIDPNTVFS------------WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPG 267
L P+ P ++ W++ N T+ +A L + G G FL+R S++SP
Sbjct: 259 PALHPAHAPQISYTGPSSSGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPS 318
Query: 268 DYSLFFHINNQIQRFRIEKKGVRYLMGGRTFECLDAVINRYRKEQI 313
D+S+ + + + F+++ Y +G R F +D ++ Y+K I
Sbjct: 319 DFSVSLKASGKNKHFKVQLVDNVYCIGQRRFHTMDELVEHYKKAPI 364
Score = 54.0 bits (124), Expect = 2e-06
Identities = 25/76 (32%), Positives = 41/76 (53%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
EWY+G + R+ +E L +G +L+R+S+ P + +S HF++ V Y
Sbjct: 284 EWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVYC 343
Query: 125 IGGRQFDSLTELVGFY 140
IG R+F ++ ELV Y
Sbjct: 344 IGQRRFHTMDELVEHY 359
>AF047487-1|AAC80284.1| 380|Homo sapiens Nck-2 protein.
Length = 380
Score = 54.0 bits (124), Expect = 2e-06
Identities = 39/166 (23%), Positives = 77/166 (46%), Gaps = 21/166 (12%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIF-FVHNDMGDGWLWVTAHRTGEQGMIFRELV------ 220
V + P++ + + +EL F+KG+ + D W + G+ G++ + V
Sbjct: 200 VQTLYPFSSVTE-EELNFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYVVVLSDG 258
Query: 221 EDLDPSIDPNTVFS------------WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPG 267
L P+ P ++ W++ N T+ +A L + G G FL+R S++SP
Sbjct: 259 PALHPAHAPQISYTGPSSSGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPS 318
Query: 268 DYSLFFHINNQIQRFRIEKKGVRYLMGGRTFECLDAVINRYRKEQI 313
D+S+ + + + F+++ Y +G R F +D ++ Y+K I
Sbjct: 319 DFSVSLKASGKNKHFKVQLVDNVYCIGQRRFHTMDELVEHYKKAPI 364
Score = 54.0 bits (124), Expect = 2e-06
Identities = 25/76 (32%), Positives = 41/76 (53%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
EWY+G + R+ +E L +G +L+R+S+ P + +S HF++ V Y
Sbjct: 284 EWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVYC 343
Query: 125 IGGRQFDSLTELVGFY 140
IG R+F ++ ELV Y
Sbjct: 344 IGQRRFHTMDELVEHY 359
>AF043119-1|AAC04831.1| 381|Homo sapiens SH2/SH3 adaptor protein
NCK-beta protein.
Length = 381
Score = 54.0 bits (124), Expect = 2e-06
Identities = 39/166 (23%), Positives = 77/166 (46%), Gaps = 21/166 (12%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIF-FVHNDMGDGWLWVTAHRTGEQGMIFRELV------ 220
V + P++ + + +EL F+KG+ + D W + G+ G++ + V
Sbjct: 201 VQTLYPFSSVTE-EELNFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYVVVLSDG 259
Query: 221 EDLDPSIDPNTVFS------------WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPG 267
L P+ P ++ W++ N T+ +A L + G G FL+R S++SP
Sbjct: 260 PALHPAHAPQISYTGPSSSGRFAGREWYYGNVTRHQAQCALNERGVEGDFLIRDSESSPS 319
Query: 268 DYSLFFHINNQIQRFRIEKKGVRYLMGGRTFECLDAVINRYRKEQI 313
D+S+ + + + F+++ Y +G R F +D ++ Y+K I
Sbjct: 320 DFSVSLKASGKNKHFKVQLVDNVYCIGQRRFHTMDELVEHYKKAPI 365
Score = 52.8 bits (121), Expect = 5e-06
Identities = 24/76 (31%), Positives = 41/76 (53%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
EWY+G + R+ ++ L +G +L+R+S+ P + +S HF++ V Y
Sbjct: 285 EWYYGNVTRHQAQCALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVYC 344
Query: 125 IGGRQFDSLTELVGFY 140
IG R+F ++ ELV Y
Sbjct: 345 IGQRRFHTMDELVEHY 360
>AC009505-1|AAY24332.1| 304|Homo sapiens unknown protein.
Length = 304
Score = 54.0 bits (124), Expect = 2e-06
Identities = 39/166 (23%), Positives = 77/166 (46%), Gaps = 21/166 (12%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIF-FVHNDMGDGWLWVTAHRTGEQGMIFRELV------ 220
V + P++ + + +EL F+KG+ + D W + G+ G++ + V
Sbjct: 124 VQTLYPFSSVTE-EELNFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYVVVLSDG 182
Query: 221 EDLDPSIDPNTVFS------------WFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPG 267
L P+ P ++ W++ N T+ +A L + G G FL+R S++SP
Sbjct: 183 PALHPAHAPQISYTGPSSSGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPS 242
Query: 268 DYSLFFHINNQIQRFRIEKKGVRYLMGGRTFECLDAVINRYRKEQI 313
D+S+ + + + F+++ Y +G R F +D ++ Y+K I
Sbjct: 243 DFSVSLKASGKNKHFKVQLVDNVYCIGQRRFHTMDELVEHYKKAPI 288
Score = 54.0 bits (124), Expect = 2e-06
Identities = 25/76 (32%), Positives = 41/76 (53%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 124
EWY+G + R+ +E L +G +L+R+S+ P + +S HF++ V Y
Sbjct: 208 EWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVYC 267
Query: 125 IGGRQFDSLTELVGFY 140
IG R+F ++ ELV Y
Sbjct: 268 IGQRRFHTMDELVEHY 283
>U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase
protein.
Length = 505
Score = 53.6 bits (123), Expect = 3e-06
Identities = 28/83 (33%), Positives = 50/83 (60%), Gaps = 3/83 (3%)
Query: 66 WYHGRLDRYTSEERL-WAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVC-GDY 123
W+ G + R +E++L ++ +K GS+L+RES+ + G + LS L + H+RI + G +
Sbjct: 116 WFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRIKRLDEGGF 175
Query: 124 YIGGRQ-FDSLTELVGFYSHCSD 145
++ R+ F +L E V Y+ SD
Sbjct: 176 FLTRRRIFSTLNEFVSHYTKTSD 198
Score = 46.0 bits (104), Expect = 6e-04
Identities = 47/169 (27%), Positives = 78/169 (46%), Gaps = 20/169 (11%)
Query: 169 VAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAH----RTGE----QGMIFRELV 220
VA+ Y + ++L+F+ GD V + + +GW W H R G QG I V
Sbjct: 48 VALFDY-QARTAEDLSFRAGDKLQVLDTLHEGW-WFARHLEKRRDGSSQQLQGYIPSNYV 105
Query: 221 -EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINN 277
ED +P WF +S+A L+ + GSFL+R S++ G++SL
Sbjct: 106 AEDRSLQAEP-----WFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGA 160
Query: 278 QIQRFRIEK--KGVRYLMGGRTFECLDAVINRYRKEQIVEGHTLGQPLI 324
++ +RI++ +G +L R F L+ ++ Y K LG+P +
Sbjct: 161 VVKHYRIKRLDEGGFFLTRRRIFSTLNEFVSHYTKTSDGLCVKLGKPCL 209
>BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 53.6 bits (123), Expect = 3e-06
Identities = 28/83 (33%), Positives = 50/83 (60%), Gaps = 3/83 (3%)
Query: 66 WYHGRLDRYTSEERL-WAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVC-GDY 123
W+ G + R +E++L ++ +K GS+L+RES+ + G + LS L + H+RI + G +
Sbjct: 116 WFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRIKRLDEGGF 175
Query: 124 YIGGRQ-FDSLTELVGFYSHCSD 145
++ R+ F +L E V Y+ SD
Sbjct: 176 FLTRRRIFSTLNEFVSHYTKTSD 198
Score = 46.0 bits (104), Expect = 6e-04
Identities = 47/169 (27%), Positives = 78/169 (46%), Gaps = 20/169 (11%)
Query: 169 VAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAH----RTGE----QGMIFRELV 220
VA+ Y + ++L+F+ GD V + + +GW W H R G QG I V
Sbjct: 48 VALFDY-QARTAEDLSFRAGDKLQVLDTLHEGW-WFARHLEKRRDGSSQQLQGYIPSNYV 105
Query: 221 -EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINN 277
ED +P WF +S+A L+ + GSFL+R S++ G++SL
Sbjct: 106 AEDRSLQAEP-----WFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGA 160
Query: 278 QIQRFRIEK--KGVRYLMGGRTFECLDAVINRYRKEQIVEGHTLGQPLI 324
++ +RI++ +G +L R F L+ ++ Y K LG+P +
Sbjct: 161 VVKHYRIKRLDEGGFFLTRRRIFSTLNEFVSHYTKTSDGLCVKLGKPCL 209
>AM491363-1|CAM33013.1| 498|Homo sapiens bcr-abl1 e19a2 chimeric
protein protein.
Length = 498
Score = 53.6 bits (123), Expect = 3e-06
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 379 WYHGPVSR-NAAEHLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 435
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 436 LYVSSESRFNTLAELVHHHSTVAD 459
Score = 46.8 bits (106), Expect = 4e-04
Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
ND VA+ + D + L+ KG+ V +N G+ W A QG + +
Sbjct: 313 NDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNHNGE---WCEAQTKNGQGWVPSNYI 368
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H +++ A +L GSFLVR S++SPG S+ ++
Sbjct: 369 TPVN-SLEKH---SWYHGPVSRNAAEHLLSSGINGSFLVRESESSPGQRSISLRYEGRVY 424
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 425 HYRINTASDGKLYVSSESRFNTLAELVHHH 454
>AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 53.6 bits (123), Expect = 3e-06
Identities = 28/83 (33%), Positives = 50/83 (60%), Gaps = 3/83 (3%)
Query: 66 WYHGRLDRYTSEERL-WAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVC-GDY 123
W+ G + R +E++L ++ +K GS+L+RES+ + G + LS L + H+RI + G +
Sbjct: 116 WFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRIKRLDEGGF 175
Query: 124 YIGGRQ-FDSLTELVGFYSHCSD 145
++ R+ F +L E V Y+ SD
Sbjct: 176 FLTRRRIFSTLNEFVSHYTKTSD 198
Score = 46.0 bits (104), Expect = 6e-04
Identities = 47/169 (27%), Positives = 78/169 (46%), Gaps = 20/169 (11%)
Query: 169 VAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAH----RTGE----QGMIFRELV 220
VA+ Y + ++L+F+ GD V + + +GW W H R G QG I V
Sbjct: 48 VALFDY-QARTAEDLSFRAGDKLQVLDTLHEGW-WFARHLEKRRDGSSQQLQGYIPSNYV 105
Query: 221 -EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINN 277
ED +P WF +S+A L+ + GSFL+R S++ G++SL
Sbjct: 106 AEDRSLQAEP-----WFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGA 160
Query: 278 QIQRFRIEK--KGVRYLMGGRTFECLDAVINRYRKEQIVEGHTLGQPLI 324
++ +RI++ +G +L R F L+ ++ Y K LG+P +
Sbjct: 161 VVKHYRIKRLDEGGFFLTRRRIFSTLNEFVSHYTKTSDGLCVKLGKPCL 209
>AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 53.6 bits (123), Expect = 3e-06
Identities = 28/83 (33%), Positives = 50/83 (60%), Gaps = 3/83 (3%)
Query: 66 WYHGRLDRYTSEERL-WAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVC-GDY 123
W+ G + R +E++L ++ +K GS+L+RES+ + G + LS L + H+RI + G +
Sbjct: 116 WFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRIKRLDEGGF 175
Query: 124 YIGGRQ-FDSLTELVGFYSHCSD 145
++ R+ F +L E V Y+ SD
Sbjct: 176 FLTRRRIFSTLNEFVSHYTKTSD 198
Score = 46.0 bits (104), Expect = 6e-04
Identities = 47/169 (27%), Positives = 78/169 (46%), Gaps = 20/169 (11%)
Query: 169 VAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAH----RTGE----QGMIFRELV 220
VA+ Y + ++L+F+ GD V + + +GW W H R G QG I V
Sbjct: 48 VALFDY-QARTAEDLSFRAGDKLQVLDTLHEGW-WFARHLEKRRDGSSQQLQGYIPSNYV 105
Query: 221 -EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINN 277
ED +P WF +S+A L+ + GSFL+R S++ G++SL
Sbjct: 106 AEDRSLQAEP-----WFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGA 160
Query: 278 QIQRFRIEK--KGVRYLMGGRTFECLDAVINRYRKEQIVEGHTLGQPLI 324
++ +RI++ +G +L R F L+ ++ Y K LG+P +
Sbjct: 161 VVKHYRIKRLDEGGFFLTRRRIFSTLNEFVSHYTKTSDGLCVKLGKPCL 209
>U47924-17|AAB51322.1| 556|Homo sapiens protein tyrosine
phosphatase 1C protein.
Length = 556
Score = 53.2 bits (122), Expect = 4e-06
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 10/87 (11%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLG---RTG------I 111
P WYHG + +E L A + ++LVRES +PG +VLS L + G +
Sbjct: 66 PTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRV 125
Query: 112 NHFRITAVCGDYYIGGRQ-FDSLTELV 137
H ++ G Y +GG + FDSLT+LV
Sbjct: 126 THIKVMCEGGRYTVGGLETFDSLTDLV 152
Score = 39.1 bits (87), Expect = 0.072
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 12/99 (12%)
Query: 228 DPNTVFSWFHPNCTKSEAVDML-VKAGPGSFLVRPSDNSPGDYSLFFHINN--------- 277
DP T W+H + + +A +L K P +FLVR S + PGD+ L +
Sbjct: 65 DP-TSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 123
Query: 278 QIQRFRIEKKGVRYLMGG-RTFECLDAVINRYRKEQIVE 315
++ ++ +G RY +GG TF+ L ++ ++K I E
Sbjct: 124 RVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEE 162
>U22322-1|AAC50116.1| 505|Homo sapiens Rak protein.
Length = 505
Score = 53.2 bits (122), Expect = 4e-06
Identities = 28/83 (33%), Positives = 50/83 (60%), Gaps = 3/83 (3%)
Query: 66 WYHGRLDRYTSEERL-WAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVC-GDY 123
W+ G + R +E++L ++ +K GS+L+RES+ + G + LS L + H+RI + G +
Sbjct: 116 WFFGAIRRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRIKRLDEGGF 175
Query: 124 YIGGRQ-FDSLTELVGFYSHCSD 145
++ R+ F +L E V Y+ SD
Sbjct: 176 FLTRRRIFSTLNEFVSHYTKTSD 198
Score = 46.8 bits (106), Expect = 4e-04
Identities = 46/168 (27%), Positives = 79/168 (47%), Gaps = 18/168 (10%)
Query: 169 VAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAH----RTGE----QGMIFRELV 220
VA+ Y + ++L+F+ GD V + + +GW W H R G QG I V
Sbjct: 48 VALFDY-QARTAEDLSFRAGDKLQVLDTLHEGW-WFARHLEKRRDGSSQQLQGYIPSNYV 105
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINNQ 278
+ D S+ +WF +S+A L+ + GSFL+R S++ G++SL
Sbjct: 106 AE-DRSLQAE---AWFFGAIRRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAV 161
Query: 279 IQRFRIEK--KGVRYLMGGRTFECLDAVINRYRKEQIVEGHTLGQPLI 324
++ +RI++ +G +L R F L+ ++ Y K LG+P +
Sbjct: 162 VKHYRIKRLDEGGFFLTRRRIFSTLNEFVSHYTKTSDGLCVKLGKPCL 209
>X73568-1|CAA51970.1| 630|Homo sapiens protein tyrosin kinase
protein.
Length = 630
Score = 52.8 bits (121), Expect = 5e-06
Identities = 35/96 (36%), Positives = 51/96 (53%), Gaps = 4/96 (4%)
Query: 57 AVLAPPETEWYHGRLDRYTSEERLWAASK-QGSYLVRESDRKPGSYVLSYLGRTGINHFR 115
A A + W+HG++ R SE+ + SK G +L+R D GSY L L + H+R
Sbjct: 154 ATTAHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNN-GSYALCLLHEGKVLHYR 212
Query: 116 ITA-VCGDYYI-GGRQFDSLTELVGFYSHCSDLLKR 149
I G I G++FD+L +LV YS+ +D L R
Sbjct: 213 IDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADPLLR 248
Score = 32.3 bits (70), Expect = 8.2
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Query: 66 WYHGRLDRYTSEERL-WAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDY 123
++ G + R +E+ L G YL+R+S G + LS +H+ I + G Y
Sbjct: 10 FFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTY 69
Query: 124 YI-GGRQFDSLTELVGFYSHCSD 145
I GGR S +L ++S SD
Sbjct: 70 AIAGGRTHASPADLCHYHSQESD 92
>X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRNA
encoding p150 protein. ).
Length = 1130
Score = 52.8 bits (121), Expect = 5e-06
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 127 WYHGPVSR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 183
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 184 LYVSSESRFNTLAELVHHHSTVAD 207
Score = 46.0 bits (104), Expect = 6e-04
Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
ND VA+ + D + L+ KG+ V +N G+ W A QG + +
Sbjct: 61 NDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNHNGE---WCEAQTKNGQGWVPSNYI 116
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H +++ A +L GSFLVR S++SPG S+ ++
Sbjct: 117 TPVN-SLEKH---SWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY 172
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 173 HYRINTASDGKLYVSSESRFNTLAELVHHH 202
>U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1130
Score = 52.8 bits (121), Expect = 5e-06
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 127 WYHGPVSR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 183
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 184 LYVSSESRFNTLAELVHHHSTVAD 207
Score = 46.0 bits (104), Expect = 6e-04
Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
ND VA+ + D + L+ KG+ V +N G+ W A QG + +
Sbjct: 61 NDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNHNGE---WCEAQTKNGQGWVPSNYI 116
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H +++ A +L GSFLVR S++SPG S+ ++
Sbjct: 117 TPVN-SLEKH---SWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY 172
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 173 HYRINTASDGKLYVSSESRFNTLAELVHHH 202
>U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1149
Score = 52.8 bits (121), Expect = 5e-06
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 146 WYHGPVSR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 202
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 203 LYVSSESRFNTLAELVHHHSTVAD 226
Score = 46.0 bits (104), Expect = 6e-04
Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
ND VA+ + D + L+ KG+ V +N G+ W A QG + +
Sbjct: 80 NDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNHNGE---WCEAQTKNGQGWVPSNYI 135
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H +++ A +L GSFLVR S++SPG S+ ++
Sbjct: 136 TPVN-SLEKH---SWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY 191
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 192 HYRINTASDGKLYVSSESRFNTLAELVHHH 221
>DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 52.8 bits (121), Expect = 5e-06
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 146 WYHGPVSR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 202
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 203 LYVSSESRFNTLAELVHHHSTVAD 226
Score = 46.0 bits (104), Expect = 6e-04
Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
ND VA+ + D + L+ KG+ V +N G+ W A QG + +
Sbjct: 80 NDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNHNGE---WCEAQTKNGQGWVPSNYI 135
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H +++ A +L GSFLVR S++SPG S+ ++
Sbjct: 136 TPVN-SLEKH---SWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY 191
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 192 HYRINTASDGKLYVSSESRFNTLAELVHHH 221
>BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 52.8 bits (121), Expect = 5e-06
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 146 WYHGPVSR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 202
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 203 LYVSSESRFNTLAELVHHHSTVAD 226
Score = 46.0 bits (104), Expect = 6e-04
Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
ND VA+ + D + L+ KG+ V +N G+ W A QG + +
Sbjct: 80 NDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNHNGE---WCEAQTKNGQGWVPSNYI 135
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H +++ A +L GSFLVR S++SPG S+ ++
Sbjct: 136 TPVN-SLEKH---SWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY 191
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 192 HYRINTASDGKLYVSSESRFNTLAELVHHH 221
>AM491362-1|CAM33012.1| 585|Homo sapiens bcr-abl1 e6a2 chimeric
protein protein.
Length = 585
Score = 52.8 bits (121), Expect = 5e-06
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 466 WYHGPVSR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 522
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 523 LYVSSESRFNTLAELVHHHSTVAD 546
Score = 46.0 bits (104), Expect = 6e-04
Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
ND VA+ + D + L+ KG+ V +N G+ W A QG + +
Sbjct: 400 NDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNHNGE---WCEAQTKNGQGWVPSNYI 455
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H +++ A +L GSFLVR S++SPG S+ ++
Sbjct: 456 TPVN-SLEKH---SWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY 511
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 512 HYRINTASDGKLYVSSESRFNTLAELVHHH 541
>AM491361-1|CAM33011.1| 313|Homo sapiens bcr-abl1 e1a3 chimeric
protein protein.
Length = 313
Score = 52.8 bits (121), Expect = 5e-06
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 194 WYHGPVSR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 250
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 251 LYVSSESRFNTLAELVHHHSTVAD 274
Score = 41.9 bits (94), Expect = 0.010
Identities = 27/108 (25%), Positives = 50/108 (46%), Gaps = 6/108 (5%)
Query: 203 WVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPS 262
W A QG + + ++ S++ + SW+H +++ A +L GSFLVR S
Sbjct: 166 WCEAQTKNGQGWVPSNYITPVN-SLEKH---SWYHGPVSRNAAEYLLSSGINGSFLVRES 221
Query: 263 DNSPGDYSLFFHINNQIQRFRIE--KKGVRYLMGGRTFECLDAVINRY 308
++SPG S+ ++ +RI G Y+ F L +++ +
Sbjct: 222 ESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHH 269
>AM491360-1|CAM33010.1| 260|Homo sapiens bcr-abl1 e14a3 chimeric
protein protein.
Length = 260
Score = 52.8 bits (121), Expect = 5e-06
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 141 WYHGPVSR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 197
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 198 LYVSSESRFNTLAELVHHHSTVAD 221
Score = 41.9 bits (94), Expect = 0.010
Identities = 27/108 (25%), Positives = 50/108 (46%), Gaps = 6/108 (5%)
Query: 203 WVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPS 262
W A QG + + ++ S++ + SW+H +++ A +L GSFLVR S
Sbjct: 113 WCEAQTKNGQGWVPSNYITPVN-SLEKH---SWYHGPVSRNAAEYLLSSGINGSFLVRES 168
Query: 263 DNSPGDYSLFFHINNQIQRFRIE--KKGVRYLMGGRTFECLDAVINRY 308
++SPG S+ ++ +RI G Y+ F L +++ +
Sbjct: 169 ESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHH 216
>AM491359-1|CAM33009.1| 235|Homo sapiens bcr-abl1 e13a3 chimeric
protein protein.
Length = 235
Score = 52.8 bits (121), Expect = 5e-06
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 116 WYHGPVSR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 172
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 173 LYVSSESRFNTLAELVHHHSTVAD 196
Score = 41.5 bits (93), Expect = 0.013
Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 234 SWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIE--KKGVRY 291
SW+H +++ A +L GSFLVR S++SPG S+ ++ +RI G Y
Sbjct: 115 SWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLY 174
Query: 292 LMGGRTFECLDAVINRY 308
+ F L +++ +
Sbjct: 175 VSSESRFNTLAELVHHH 191
>AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 52.8 bits (121), Expect = 5e-06
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 146 WYHGPVSR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 202
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 203 LYVSSESRFNTLAELVHHHSTVAD 226
Score = 46.0 bits (104), Expect = 6e-04
Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
ND VA+ + D + L+ KG+ V +N G+ W A QG + +
Sbjct: 80 NDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNHNGE---WCEAQTKNGQGWVPSNYI 135
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H +++ A +L GSFLVR S++SPG S+ ++
Sbjct: 136 TPVN-SLEKH---SWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY 191
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 192 HYRINTASDGKLYVSSESRFNTLAELVHHH 221
>AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 52.8 bits (121), Expect = 5e-06
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 146 WYHGPVSR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 202
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 203 LYVSSESRFNTLAELVHHHSTVAD 226
Score = 46.0 bits (104), Expect = 6e-04
Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
ND VA+ + D + L+ KG+ V +N G+ W A QG + +
Sbjct: 80 NDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNHNGE---WCEAQTKNGQGWVPSNYI 135
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H +++ A +L GSFLVR S++SPG S+ ++
Sbjct: 136 TPVN-SLEKH---SWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY 191
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 192 HYRINTASDGKLYVSSESRFNTLAELVHHH 221
>AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1130
Score = 52.8 bits (121), Expect = 5e-06
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 127 WYHGPVSR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 183
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 184 LYVSSESRFNTLAELVHHHSTVAD 207
Score = 46.0 bits (104), Expect = 6e-04
Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
ND VA+ + D + L+ KG+ V +N G+ W A QG + +
Sbjct: 61 NDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNHNGE---WCEAQTKNGQGWVPSNYI 116
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H +++ A +L GSFLVR S++SPG S+ ++
Sbjct: 117 TPVN-SLEKH---SWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY 172
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 173 HYRINTASDGKLYVSSESRFNTLAELVHHH 202
>AJ131467-1|CAA10377.1| 307|Homo sapiens BCR/ABL chimeric fusion
peptide protein.
Length = 307
Score = 52.8 bits (121), Expect = 5e-06
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 200 WYHGPVSR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 256
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 257 LYVSSESRFNTLAELVHHHSTVAD 280
Score = 46.0 bits (104), Expect = 6e-04
Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
ND VA+ + D + L+ KG+ V +N G+ W A QG + +
Sbjct: 134 NDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNHNGE---WCEAQTKNGQGWVPSNYI 189
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H +++ A +L GSFLVR S++SPG S+ ++
Sbjct: 190 TPVN-SLEKH---SWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY 245
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 246 HYRINTASDGKLYVSSESRFNTLAELVHHH 275
>AJ131466-1|CAA10376.1| 332|Homo sapiens BCR/ABL (major breakpoint)
fusion peptide protein.
Length = 332
Score = 52.8 bits (121), Expect = 5e-06
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 225 WYHGPVSR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 281
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 282 LYVSSESRFNTLAELVHHHSTVAD 305
Score = 46.0 bits (104), Expect = 6e-04
Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
ND VA+ + D + L+ KG+ V +N G+ W A QG + +
Sbjct: 159 NDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNHNGE---WCEAQTKNGQGWVPSNYI 214
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H +++ A +L GSFLVR S++SPG S+ ++
Sbjct: 215 TPVN-SLEKH---SWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY 270
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 271 HYRINTASDGKLYVSSESRFNTLAELVHHH 300
>AF113911-1|AAD04633.1| 359|Homo sapiens BCR-ABL minor breakpoint
peptide protein.
Length = 359
Score = 52.8 bits (121), Expect = 5e-06
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 252 WYHGPVSR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 308
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 309 LYVSSESRFNTLAELVHHHSTVAD 332
Score = 46.0 bits (104), Expect = 6e-04
Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
ND VA+ + D + L+ KG+ V +N G+ W A QG + +
Sbjct: 186 NDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNHNGE---WCEAQTKNGQGWVPSNYI 241
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H +++ A +L GSFLVR S++SPG S+ ++
Sbjct: 242 TPVN-SLEKH---SWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY 297
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 298 HYRINTASDGKLYVSSESRFNTLAELVHHH 327
>AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 isoform b variant
protein.
Length = 1167
Score = 52.8 bits (121), Expect = 5e-06
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R + E L ++ GS+LVRES+ PG S L Y GR + H+RI TA G
Sbjct: 164 WYHGPVSR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGR--VYHYRINTASDGK 220
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 221 LYVSSESRFNTLAELVHHHSTVAD 244
Score = 46.0 bits (104), Expect = 6e-04
Identities = 38/150 (25%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
ND VA+ + D + L+ KG+ V +N G+ W A QG + +
Sbjct: 98 NDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNHNGE---WCEAQTKNGQGWVPSNYI 153
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H +++ A +L GSFLVR S++SPG S+ ++
Sbjct: 154 TPVN-SLEKH---SWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVY 209
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 210 HYRINTASDGKLYVSSESRFNTLAELVHHH 239
>Z29630-1|CAA82737.1| 612|Homo sapiens protein-tyrosine kinase
protein.
Length = 612
Score = 52.4 bits (120), Expect = 7e-06
Identities = 35/96 (36%), Positives = 51/96 (53%), Gaps = 4/96 (4%)
Query: 57 AVLAPPETEWYHGRLDRYTSEERLWAASK-QGSYLVRESDRKPGSYVLSYLGRTGINHFR 115
A A + W+HG++ R SE+ + SK G +L+R D GSY L L + H+R
Sbjct: 159 ATTAHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNN-GSYALCLLHEGKVLHYR 217
Query: 116 ITA-VCGDYYI-GGRQFDSLTELVGFYSHCSDLLKR 149
I G I G++FD+L +LV YS+ +D L R
Sbjct: 218 IDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLR 253
Score = 32.3 bits (70), Expect = 8.2
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Query: 66 WYHGRLDRYTSEERL-WAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDY 123
++ G + R +E+ L G YL+R+S G + LS +H+ I + G Y
Sbjct: 15 FFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTY 74
Query: 124 YI-GGRQFDSLTELVGFYSHCSD 145
I GGR S +L ++S SD
Sbjct: 75 AIAGGRTHASPADLCHYHSQESD 97
>L28824-1|AAA36526.1| 635|Homo sapiens protein tyrosine kinase
protein.
Length = 635
Score = 52.4 bits (120), Expect = 7e-06
Identities = 35/96 (36%), Positives = 51/96 (53%), Gaps = 4/96 (4%)
Query: 57 AVLAPPETEWYHGRLDRYTSEERLWAASK-QGSYLVRESDRKPGSYVLSYLGRTGINHFR 115
A A + W+HG++ R SE+ + SK G +L+R D GSY L L + H+R
Sbjct: 159 ATTAHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNN-GSYALCLLHEGKVLHYR 217
Query: 116 ITA-VCGDYYI-GGRQFDSLTELVGFYSHCSDLLKR 149
I G I G++FD+L +LV YS+ +D L R
Sbjct: 218 IDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLR 253
Score = 32.3 bits (70), Expect = 8.2
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Query: 66 WYHGRLDRYTSEERL-WAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDY 123
++ G + R +E+ L G YL+R+S G + LS +H+ I + G Y
Sbjct: 15 FFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTY 74
Query: 124 YI-GGRQFDSLTELVGFYSHCSD 145
I GGR S +L ++S SD
Sbjct: 75 AIAGGRTHASPADLCHYHSQESD 97
>BT007277-1|AAP35941.1| 304|Homo sapiens v-crk sarcoma virus CT10
oncogene homolog (avian) protein.
Length = 304
Score = 52.4 bits (120), Expect = 7e-06
Identities = 50/185 (27%), Positives = 76/185 (41%), Gaps = 24/185 (12%)
Query: 64 TEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA----- 118
+ WY GRL R + L + G +LVR+S PG YVLS + ++H+ I +
Sbjct: 11 SSWYWGRLSRQEAVALL-QGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPRP 69
Query: 119 -------------VCGDYYIGGRQFDSLTELVGFYS-HCSD---LLKRERLXXXXXXXXX 161
IG ++FDSL L+ FY H D L++
Sbjct: 70 PVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVSRSRQGSGVIL 129
Query: 162 XNDKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVE 221
++ V L D ++L F+KGDI + + + W W G++GMI VE
Sbjct: 130 RQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQW-WNAEDSEGKRGMIPVPYVE 188
Query: 222 DLDPS 226
P+
Sbjct: 189 KYRPA 193
Score = 44.0 bits (99), Expect = 0.003
Identities = 22/57 (38%), Positives = 30/57 (52%)
Query: 234 SWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVR 290
SW+ ++ EAV +L G FLVR S SPGDY L N+++ + I G R
Sbjct: 12 SWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPR 68
>BC011399-1|AAH11399.1| 612|Homo sapiens SYK protein protein.
Length = 612
Score = 52.4 bits (120), Expect = 7e-06
Identities = 35/96 (36%), Positives = 51/96 (53%), Gaps = 4/96 (4%)
Query: 57 AVLAPPETEWYHGRLDRYTSEERLWAASK-QGSYLVRESDRKPGSYVLSYLGRTGINHFR 115
A A + W+HG++ R SE+ + SK G +L+R D GSY L L + H+R
Sbjct: 159 ATTAHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNN-GSYALCLLHEGKVLHYR 217
Query: 116 ITA-VCGDYYI-GGRQFDSLTELVGFYSHCSDLLKR 149
I G I G++FD+L +LV YS+ +D L R
Sbjct: 218 IDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLR 253
Score = 32.3 bits (70), Expect = 8.2
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Query: 66 WYHGRLDRYTSEERL-WAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDY 123
++ G + R +E+ L G YL+R+S G + LS +H+ I + G Y
Sbjct: 15 FFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTY 74
Query: 124 YI-GGRQFDSLTELVGFYSHCSD 145
I GGR S +L ++S SD
Sbjct: 75 AIAGGRTHASPADLCHYHSQESD 97
>BC009837-1|AAH09837.1| 204|Homo sapiens v-crk sarcoma virus CT10
oncogene homolog (avian) protein.
Length = 204
Score = 52.4 bits (120), Expect = 7e-06
Identities = 50/185 (27%), Positives = 76/185 (41%), Gaps = 24/185 (12%)
Query: 64 TEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA----- 118
+ WY GRL R + L + G +LVR+S PG YVLS + ++H+ I +
Sbjct: 11 SSWYWGRLSRQEAVALL-QGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPRP 69
Query: 119 -------------VCGDYYIGGRQFDSLTELVGFYS-HCSD---LLKRERLXXXXXXXXX 161
IG ++FDSL L+ FY H D L++
Sbjct: 70 PVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVSRSRQGSGVIL 129
Query: 162 XNDKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVE 221
++ V L D ++L F+KGDI + + + W W G++GMI VE
Sbjct: 130 RQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQW-WNAEDSEGKRGMIPVPYVE 188
Query: 222 DLDPS 226
P+
Sbjct: 189 KYRPA 193
Score = 44.0 bits (99), Expect = 0.003
Identities = 22/57 (38%), Positives = 30/57 (52%)
Query: 234 SWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVR 290
SW+ ++ EAV +L G FLVR S SPGDY L N+++ + I G R
Sbjct: 12 SWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPR 68
>BC008506-1|AAH08506.1| 304|Homo sapiens v-crk sarcoma virus CT10
oncogene homolog (avian) protein.
Length = 304
Score = 52.4 bits (120), Expect = 7e-06
Identities = 50/185 (27%), Positives = 76/185 (41%), Gaps = 24/185 (12%)
Query: 64 TEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA----- 118
+ WY GRL R + L + G +LVR+S PG YVLS + ++H+ I +
Sbjct: 11 SSWYWGRLSRQEAVALL-QGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPRP 69
Query: 119 -------------VCGDYYIGGRQFDSLTELVGFYS-HCSD---LLKRERLXXXXXXXXX 161
IG ++FDSL L+ FY H D L++
Sbjct: 70 PVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVSRSRQGSGVIL 129
Query: 162 XNDKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVE 221
++ V L D ++L F+KGDI + + + W W G++GMI VE
Sbjct: 130 RQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQW-WNAEDSEGKRGMIPVPYVE 188
Query: 222 DLDPS 226
P+
Sbjct: 189 KYRPA 193
Score = 44.0 bits (99), Expect = 0.003
Identities = 22/57 (38%), Positives = 30/57 (52%)
Query: 234 SWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVR 290
SW+ ++ EAV +L G FLVR S SPGDY L N+++ + I G R
Sbjct: 12 SWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPR 68
>BC002962-1|AAH02962.1| 635|Homo sapiens spleen tyrosine kinase
protein.
Length = 635
Score = 52.4 bits (120), Expect = 7e-06
Identities = 35/96 (36%), Positives = 51/96 (53%), Gaps = 4/96 (4%)
Query: 57 AVLAPPETEWYHGRLDRYTSEERLWAASK-QGSYLVRESDRKPGSYVLSYLGRTGINHFR 115
A A + W+HG++ R SE+ + SK G +L+R D GSY L L + H+R
Sbjct: 159 ATTAHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNN-GSYALCLLHEGKVLHYR 217
Query: 116 ITA-VCGDYYI-GGRQFDSLTELVGFYSHCSDLLKR 149
I G I G++FD+L +LV YS+ +D L R
Sbjct: 218 IDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLR 253
Score = 32.3 bits (70), Expect = 8.2
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Query: 66 WYHGRLDRYTSEERL-WAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDY 123
++ G + R +E+ L G YL+R+S G + LS +H+ I + G Y
Sbjct: 15 FFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTY 74
Query: 124 YI-GGRQFDSLTELVGFYSHCSD 145
I GGR S +L ++S SD
Sbjct: 75 AIAGGRTHASPADLCHYHSQESD 97
>BC001718-1|AAH01718.1| 304|Homo sapiens v-crk sarcoma virus CT10
oncogene homolog (avian) protein.
Length = 304
Score = 52.4 bits (120), Expect = 7e-06
Identities = 50/185 (27%), Positives = 76/185 (41%), Gaps = 24/185 (12%)
Query: 64 TEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA----- 118
+ WY GRL R + L + G +LVR+S PG YVLS + ++H+ I +
Sbjct: 11 SSWYWGRLSRQEAVALL-QGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPRP 69
Query: 119 -------------VCGDYYIGGRQFDSLTELVGFYS-HCSD---LLKRERLXXXXXXXXX 161
IG ++FDSL L+ FY H D L++
Sbjct: 70 PVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVSRSRQGSGVIL 129
Query: 162 XNDKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVE 221
++ V L D ++L F+KGDI + + + W W G++GMI VE
Sbjct: 130 RQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQW-WNAEDSEGKRGMIPVPYVE 188
Query: 222 DLDPS 226
P+
Sbjct: 189 KYRPA 193
Score = 44.0 bits (99), Expect = 0.003
Identities = 22/57 (38%), Positives = 30/57 (52%)
Query: 234 SWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVR 290
SW+ ++ EAV +L G FLVR S SPGDY L N+++ + I G R
Sbjct: 12 SWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPR 68
>BC001645-1|AAH01645.1| 635|Homo sapiens spleen tyrosine kinase
protein.
Length = 635
Score = 52.4 bits (120), Expect = 7e-06
Identities = 35/96 (36%), Positives = 51/96 (53%), Gaps = 4/96 (4%)
Query: 57 AVLAPPETEWYHGRLDRYTSEERLWAASK-QGSYLVRESDRKPGSYVLSYLGRTGINHFR 115
A A + W+HG++ R SE+ + SK G +L+R D GSY L L + H+R
Sbjct: 159 ATTAHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNN-GSYALCLLHEGKVLHYR 217
Query: 116 ITA-VCGDYYI-GGRQFDSLTELVGFYSHCSDLLKR 149
I G I G++FD+L +LV YS+ +D L R
Sbjct: 218 IDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLR 253
Score = 32.3 bits (70), Expect = 8.2
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Query: 66 WYHGRLDRYTSEERL-WAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDY 123
++ G + R +E+ L G YL+R+S G + LS +H+ I + G Y
Sbjct: 15 FFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTY 74
Query: 124 YI-GGRQFDSLTELVGFYSHCSD 145
I GGR S +L ++S SD
Sbjct: 75 AIAGGRTHASPADLCHYHSQESD 97
>AL354862-3|CAI16875.1| 612|Homo sapiens spleen tyrosine kinase
protein.
Length = 612
Score = 52.4 bits (120), Expect = 7e-06
Identities = 35/96 (36%), Positives = 51/96 (53%), Gaps = 4/96 (4%)
Query: 57 AVLAPPETEWYHGRLDRYTSEERLWAASK-QGSYLVRESDRKPGSYVLSYLGRTGINHFR 115
A A + W+HG++ R SE+ + SK G +L+R D GSY L L + H+R
Sbjct: 159 ATTAHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNN-GSYALCLLHEGKVLHYR 217
Query: 116 ITA-VCGDYYI-GGRQFDSLTELVGFYSHCSDLLKR 149
I G I G++FD+L +LV YS+ +D L R
Sbjct: 218 IDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLR 253
Score = 32.3 bits (70), Expect = 8.2
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Query: 66 WYHGRLDRYTSEERL-WAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDY 123
++ G + R +E+ L G YL+R+S G + LS +H+ I + G Y
Sbjct: 15 FFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTY 74
Query: 124 YI-GGRQFDSLTELVGFYSHCSD 145
I GGR S +L ++S SD
Sbjct: 75 AIAGGRTHASPADLCHYHSQESD 97
>AL354862-2|CAI16876.1| 635|Homo sapiens spleen tyrosine kinase
protein.
Length = 635
Score = 52.4 bits (120), Expect = 7e-06
Identities = 35/96 (36%), Positives = 51/96 (53%), Gaps = 4/96 (4%)
Query: 57 AVLAPPETEWYHGRLDRYTSEERLWAASK-QGSYLVRESDRKPGSYVLSYLGRTGINHFR 115
A A + W+HG++ R SE+ + SK G +L+R D GSY L L + H+R
Sbjct: 159 ATTAHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNN-GSYALCLLHEGKVLHYR 217
Query: 116 ITA-VCGDYYI-GGRQFDSLTELVGFYSHCSDLLKR 149
I G I G++FD+L +LV YS+ +D L R
Sbjct: 218 IDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLR 253
Score = 32.3 bits (70), Expect = 8.2
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Query: 66 WYHGRLDRYTSEERL-WAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDY 123
++ G + R +E+ L G YL+R+S G + LS +H+ I + G Y
Sbjct: 15 FFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTY 74
Query: 124 YI-GGRQFDSLTELVGFYSHCSD 145
I GGR S +L ++S SD
Sbjct: 75 AIAGGRTHASPADLCHYHSQESD 97
>D10656-1|BAA01505.1| 304|Homo sapiens CRK-II protein.
Length = 304
Score = 52.0 bits (119), Expect = 9e-06
Identities = 50/185 (27%), Positives = 76/185 (41%), Gaps = 24/185 (12%)
Query: 64 TEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITA----- 118
+ WY GRL R + L + G +LVR+S PG YVLS + ++H+ I +
Sbjct: 11 SSWYWGRLSRQEAVALL-QGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPRP 69
Query: 119 -------------VCGDYYIGGRQFDSLTELVGFYS-HCSD---LLKRERLXXXXXXXXX 161
IG ++FDSL L+ FY H D L++
Sbjct: 70 PVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYWDTTTLIEPVSRSRQGSGVIL 129
Query: 162 XNDKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVE 221
++ V L D ++L F+KGDI + + + W W G++GMI VE
Sbjct: 130 RQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQW-WNAEDSEGKRGMIPVPYVE 188
Query: 222 DLDPS 226
P+
Sbjct: 189 KYRPA 193
Score = 44.0 bits (99), Expect = 0.003
Identities = 22/57 (38%), Positives = 30/57 (52%)
Query: 234 SWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVR 290
SW+ ++ EAV +L G FLVR S SPGDY L N+++ + I G R
Sbjct: 12 SWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPR 68
>Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 485
Score = 51.2 bits (117), Expect = 2e-05
Identities = 32/89 (35%), Positives = 52/89 (58%), Gaps = 8/89 (8%)
Query: 65 EWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSY-----LGRTGINHFRITA 118
EWY G+L R +E +L + + +G++L+RES+ G+Y LS + + H++I
Sbjct: 99 EWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRK 158
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSD 145
+ G YYI R QF++L +LV YS +D
Sbjct: 159 LDNGGYYITTRAQFETLQQLVQHYSEKAD 187
>Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 534
Score = 51.2 bits (117), Expect = 2e-05
Identities = 32/89 (35%), Positives = 52/89 (58%), Gaps = 8/89 (8%)
Query: 65 EWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSY-----LGRTGINHFRITA 118
EWY G+L R +E +L + + +G++L+RES+ G+Y LS + + H++I
Sbjct: 148 EWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRK 207
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSD 145
+ G YYI R QF++L +LV YS +D
Sbjct: 208 LDNGGYYITTRAQFETLQQLVQHYSEKAD 236
Score = 48.8 bits (111), Expect = 9e-05
Identities = 48/176 (27%), Positives = 76/176 (43%), Gaps = 18/176 (10%)
Query: 169 VAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
VA+ Y + D+L+F KG+ F + N W + TGE G I V +D SI
Sbjct: 88 VALYDYEARTE-DDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVD-SIQ 145
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFH-----INNQIQR 281
W+ + +A L+ G G+FL+R S+ + G YSL + ++
Sbjct: 146 AE---EWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKH 202
Query: 282 FRIEK--KGVRYLMGGRTFECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQS 335
++I K G Y+ FE L ++ Y ++ +G +IA T PQ S
Sbjct: 203 YKIRKLDNGGYYITTRAQFETLQQLVQHYSEK--ADGLCFNLTVIASSCT--PQTS 254
>Z22641-1|CAA80354.1| 459|Homo sapiens a2-chimaerin protein.
Length = 459
Score = 51.2 bits (117), Expect = 2e-05
Identities = 25/71 (35%), Positives = 46/71 (64%), Gaps = 3/71 (4%)
Query: 67 YHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYIG 126
+HG + R +++ L A +GSYL+RES R+PG+Y L+ + +FR+ G +++G
Sbjct: 50 FHGMISREAADQLLIVA--EGSYLIRESQRQPGTYTLALRFGSQTRNFRL-YYDGKHFVG 106
Query: 127 GRQFDSLTELV 137
++F+S+ +LV
Sbjct: 107 EKRFESIHDLV 117
Score = 44.0 bits (99), Expect = 0.003
Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Query: 236 FHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGG 295
FH ++ EA D L+ GS+L+R S PG Y+L +Q + FR+ G ++ +G
Sbjct: 50 FHGMISR-EAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDG-KHFVGE 107
Query: 296 RTFECLDAVI 305
+ FE + ++
Sbjct: 108 KRFESIHDLV 117
>S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)
protein.
Length = 534
Score = 51.2 bits (117), Expect = 2e-05
Identities = 32/89 (35%), Positives = 52/89 (58%), Gaps = 8/89 (8%)
Query: 65 EWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSY-----LGRTGINHFRITA 118
EWY G+L R +E +L + + +G++L+RES+ G+Y LS + + H++I
Sbjct: 148 EWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRK 207
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSD 145
+ G YYI R QF++L +LV YS +D
Sbjct: 208 LDNGGYYITTRAQFETLQQLVQHYSEKAD 236
Score = 48.8 bits (111), Expect = 9e-05
Identities = 48/176 (27%), Positives = 76/176 (43%), Gaps = 18/176 (10%)
Query: 169 VAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
VA+ Y + D+L+F KG+ F + N W + TGE G I V +D SI
Sbjct: 88 VALYDYEARTE-DDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVD-SIQ 145
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFH-----INNQIQR 281
W+ + +A L+ G G+FL+R S+ + G YSL + ++
Sbjct: 146 AE---EWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKH 202
Query: 282 FRIEK--KGVRYLMGGRTFECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQS 335
++I K G Y+ FE L ++ Y ++ +G +IA T PQ S
Sbjct: 203 YKIRKLDNGGYYITTRAQFETLQQLVQHYSEK--ADGLCFNLTVIASSCT--PQTS 254
>M19722-1|AAA52451.1| 529|Homo sapiens FGR protein.
Length = 529
Score = 51.2 bits (117), Expect = 2e-05
Identities = 32/89 (35%), Positives = 50/89 (56%), Gaps = 8/89 (8%)
Query: 65 EWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLS-----YLGRTGINHFRITA 118
EWY G++ R +E +L + + QG++L+RES+ G+Y LS + H++I
Sbjct: 143 EWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHVKHYKIRK 202
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSD 145
+ G YYI R QF+S+ ELV Y +D
Sbjct: 203 LDMGGYYITTRVQFNSVQELVQHYMEVND 231
Score = 46.8 bits (106), Expect = 4e-04
Identities = 37/130 (28%), Positives = 61/130 (46%), Gaps = 8/130 (6%)
Query: 169 VAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
+A+ Y + D+LTF KG+ F + N+ W + +G+ G I V +D SI
Sbjct: 83 IALYDYEARTE-DDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVAPVD-SIQ 140
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK 286
W+ + +A L+ G G+FL+R S+ + G YSL +Q + ++
Sbjct: 141 AE---EWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHVKH 197
Query: 287 KGVRYL-MGG 295
+R L MGG
Sbjct: 198 YKIRKLDMGG 207
>M12724-1|AAA52762.1| 306|Homo sapiens FGR protein.
Length = 306
Score = 51.2 bits (117), Expect = 2e-05
Identities = 32/89 (35%), Positives = 50/89 (56%), Gaps = 8/89 (8%)
Query: 65 EWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLS-----YLGRTGINHFRITA 118
EWY G++ R +E +L + + QG++L+RES+ G+Y LS + H++I
Sbjct: 33 EWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHVKHYKIRK 92
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSD 145
+ G YYI R QF+S+ ELV Y +D
Sbjct: 93 LDMGGYYITTRVQFNSVQELVQHYMEVND 121
>BC131536-1|AAI31537.1| 1631|Homo sapiens IQ motif containing GTPase
activating protein 3 protein.
Length = 1631
Score = 51.2 bits (117), Expect = 2e-05
Identities = 37/138 (26%), Positives = 67/138 (48%), Gaps = 5/138 (3%)
Query: 737 LLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRT-RVVSGFIFLRLIC 795
LL + D+ L+I +S + P +RY+ L+ K+P+ +VV ++ R +
Sbjct: 1122 LLAMTDKFLLAITSSVDQIPYGMRYVAKVLKATLAEKFPDATDSEVYKVVGNLLYYRFLN 1181
Query: 796 PALVEPRAWTLVQRAPP---PHAQRSLL-MVAKCLQNLANLVEFGAKEPYMEVVNPFILK 851
PA+V P A+ +V A QR L VA+ LQ+ A F + ++ V+N ++ +
Sbjct: 1182 PAVVAPDAFDIVAMAAGGALAAPQRHALGAVAQLLQHAAAGKAFSGQSQHLRVLNDYLEE 1241
Query: 852 NKERMVVFLDQLSNVPDP 869
+ F+ + VP+P
Sbjct: 1242 THLKFRKFIHRACQVPEP 1259
Score = 32.7 bits (71), Expect = 6.2
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 170 AILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDP 229
+++P K+ D ++L +Q + F H D + WL AH G F E + D P
Sbjct: 78 SVVPLKKIYDVEQLRYQATGLHFRHTDNINFWLSAIAH-IGLPSTFFPETTDIYDKKNMP 136
Query: 230 NTVF 233
V+
Sbjct: 137 RVVY 140
>BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline
sarcoma viral (v-fgr) oncogene homolog protein.
Length = 529
Score = 51.2 bits (117), Expect = 2e-05
Identities = 32/89 (35%), Positives = 50/89 (56%), Gaps = 8/89 (8%)
Query: 65 EWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLS-----YLGRTGINHFRITA 118
EWY G++ R +E +L + + QG++L+RES+ G+Y LS + H++I
Sbjct: 143 EWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHVKHYKIRK 202
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSD 145
+ G YYI R QF+S+ ELV Y +D
Sbjct: 203 LDMGGYYITTRVQFNSVQELVQHYMEVND 231
Score = 46.8 bits (106), Expect = 4e-04
Identities = 37/130 (28%), Positives = 61/130 (46%), Gaps = 8/130 (6%)
Query: 169 VAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
+A+ Y + D+LTF KG+ F + N+ W + +G+ G I V +D SI
Sbjct: 83 IALYDYEARTE-DDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVAPVD-SIQ 140
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK 286
W+ + +A L+ G G+FL+R S+ + G YSL +Q + ++
Sbjct: 141 AE---EWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHVKH 197
Query: 287 KGVRYL-MGG 295
+R L MGG
Sbjct: 198 YKIRKLDMGG 207
>BC011393-1|AAH11393.1| 459|Homo sapiens chimerin (chimaerin) 1
protein.
Length = 459
Score = 51.2 bits (117), Expect = 2e-05
Identities = 25/71 (35%), Positives = 46/71 (64%), Gaps = 3/71 (4%)
Query: 67 YHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYIG 126
+HG + R +++ L A +GSYL+RES R+PG+Y L+ + +FR+ G +++G
Sbjct: 50 FHGMISREAADQLLIVA--EGSYLIRESQRQPGTYTLALRFGSQTRNFRL-YYDGKHFVG 106
Query: 127 GRQFDSLTELV 137
++F+S+ +LV
Sbjct: 107 EKRFESIHDLV 117
Score = 44.0 bits (99), Expect = 0.003
Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Query: 236 FHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGG 295
FH ++ EA D L+ GS+L+R S PG Y+L +Q + FR+ G ++ +G
Sbjct: 50 FHGMISR-EAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDG-KHFVGE 107
Query: 296 RTFECLDAVI 305
+ FE + ++
Sbjct: 108 KRFESIHDLV 117
>AY253300-1|AAP06954.1| 1631|Homo sapiens IQGAP3 protein.
Length = 1631
Score = 51.2 bits (117), Expect = 2e-05
Identities = 37/138 (26%), Positives = 67/138 (48%), Gaps = 5/138 (3%)
Query: 737 LLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRT-RVVSGFIFLRLIC 795
LL + D+ L+I +S + P +RY+ L+ K+P+ +VV ++ R +
Sbjct: 1122 LLAMTDKFLLAITSSVDQIPYGMRYVAKVLKATLAEKFPDATDSEVYKVVGNLLYYRFLN 1181
Query: 796 PALVEPRAWTLVQRAPP---PHAQRSLL-MVAKCLQNLANLVEFGAKEPYMEVVNPFILK 851
PA+V P A+ +V A QR L VA+ LQ+ A F + ++ V+N ++ +
Sbjct: 1182 PAVVAPDAFDIVAMAAGGALAAPQRHALGAVAQLLQHAAAGKAFSGQSQHLRVLNDYLEE 1241
Query: 852 NKERMVVFLDQLSNVPDP 869
+ F+ + VP+P
Sbjct: 1242 THLKFRKFIHRACQVPEP 1259
Score = 32.7 bits (71), Expect = 6.2
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 170 AILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDP 229
+++P K+ D ++L +Q + F H D + WL AH G F E + D P
Sbjct: 78 SVVPLKKIYDVEQLRYQATGLHFRHTDNINFWLSAIAH-IGLPSTFFPETTDIYDKKNMP 136
Query: 230 NTVF 233
V+
Sbjct: 137 RVVY 140
>AL365274-3|CAH72156.2| 229|Homo sapiens DAB2 interacting protein
protein.
Length = 229
Score = 51.2 bits (117), Expect = 2e-05
Identities = 55/203 (27%), Positives = 92/203 (45%), Gaps = 28/203 (13%)
Query: 421 VHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGR 480
VH S+ +++CF++ S + +A E W+E LR P + + R
Sbjct: 36 VHSSILGQDYCFEVTTS-----SGSKCFSCRSAAERDKWMENLRRAVHPNKDNSR----R 86
Query: 481 VSWVLWLRVRCLTAHRLPARLAPRPHL-RVLLGAAPVARTRPRPSPDP-HWXXXXXXXXM 538
V +L L V + A LPA+ + +L + L ART + D W +
Sbjct: 87 VEHILKLWV--IEAKDLPAK---KKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNL 141
Query: 539 PPDVTSLTITVH---NTGKRGKE---SEVAELTIELANLANGEEIEEWYPLVGMTPIGEW 592
PP T+TVH T K+ K+ S + +++ A++A + +E+WYP+V P G
Sbjct: 142 PP---LRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPVVTPNPKGGK 198
Query: 593 G---SLRLRIRYMQELVMPREEY 612
G +R++ RY ++P E Y
Sbjct: 199 GPGPMIRIKARYQTITILPMEMY 221
>AL365181-1|CAI13046.1| 1631|Homo sapiens IQ motif containing GTPase
activating protein 3 protein.
Length = 1631
Score = 51.2 bits (117), Expect = 2e-05
Identities = 37/138 (26%), Positives = 67/138 (48%), Gaps = 5/138 (3%)
Query: 737 LLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRT-RVVSGFIFLRLIC 795
LL + D+ L+I +S + P +RY+ L+ K+P+ +VV ++ R +
Sbjct: 1122 LLAMTDKFLLAITSSVDQIPYGMRYVAKVLKATLAEKFPDATDSEVYKVVGNLLYYRFLN 1181
Query: 796 PALVEPRAWTLVQRAPP---PHAQRSLL-MVAKCLQNLANLVEFGAKEPYMEVVNPFILK 851
PA+V P A+ +V A QR L VA+ LQ+ A F + ++ V+N ++ +
Sbjct: 1182 PAVVAPDAFDIVAMAAGGALAAPQRHALGAVAQLLQHAAAGKAFSGQSQHLRVLNDYLEE 1241
Query: 852 NKERMVVFLDQLSNVPDP 869
+ F+ + VP+P
Sbjct: 1242 THLKFRKFIHRACQVPEP 1259
Score = 32.7 bits (71), Expect = 6.2
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 170 AILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDP 229
+++P K+ D ++L +Q + F H D + WL AH G F E + D P
Sbjct: 78 SVVPLKKIYDVEQLRYQATGLHFRHTDNINFWLSAIAH-IGLPSTFFPETTDIYDKKNMP 136
Query: 230 NTVF 233
V+
Sbjct: 137 RVVY 140
>AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline
sarcoma viral (v-fgr) oncogene homolog protein.
Length = 529
Score = 51.2 bits (117), Expect = 2e-05
Identities = 32/89 (35%), Positives = 50/89 (56%), Gaps = 8/89 (8%)
Query: 65 EWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLS-----YLGRTGINHFRITA 118
EWY G++ R +E +L + + QG++L+RES+ G+Y LS + H++I
Sbjct: 143 EWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHVKHYKIRK 202
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSD 145
+ G YYI R QF+S+ ELV Y +D
Sbjct: 203 LDMGGYYITTRVQFNSVQELVQHYMEVND 231
Score = 46.8 bits (106), Expect = 4e-04
Identities = 37/130 (28%), Positives = 61/130 (46%), Gaps = 8/130 (6%)
Query: 169 VAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
+A+ Y + D+LTF KG+ F + N+ W + +G+ G I V +D SI
Sbjct: 83 IALYDYEARTE-DDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVAPVD-SIQ 140
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK 286
W+ + +A L+ G G+FL+R S+ + G YSL +Q + ++
Sbjct: 141 AE---EWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHVKH 197
Query: 287 KGVRYL-MGG 295
+R L MGG
Sbjct: 198 YKIRKLDMGG 207
>AL031729-2|CAI19617.1| 313|Homo sapiens Gardner-Rasheed feline
sarcoma viral (v-fgr) oncogene homolog protein.
Length = 313
Score = 51.2 bits (117), Expect = 2e-05
Identities = 32/89 (35%), Positives = 50/89 (56%), Gaps = 8/89 (8%)
Query: 65 EWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLS-----YLGRTGINHFRITA 118
EWY G++ R +E +L + + QG++L+RES+ G+Y LS + H++I
Sbjct: 143 EWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHVKHYKIRK 202
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSD 145
+ G YYI R QF+S+ ELV Y +D
Sbjct: 203 LDMGGYYITTRVQFNSVQELVQHYMEVND 231
Score = 46.8 bits (106), Expect = 4e-04
Identities = 37/130 (28%), Positives = 61/130 (46%), Gaps = 8/130 (6%)
Query: 169 VAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
+A+ Y + D+LTF KG+ F + N+ W + +G+ G I V +D SI
Sbjct: 83 IALYDYEARTE-DDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVAPVD-SIQ 140
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEK 286
W+ + +A L+ G G+FL+R S+ + G YSL +Q + ++
Sbjct: 141 AE---EWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHVKH 197
Query: 287 KGVRYL-MGG 295
+R L MGG
Sbjct: 198 YKIRKLDMGG 207
>AK122653-1|BAC85501.1| 1023|Homo sapiens protein.
Length = 1023
Score = 51.2 bits (117), Expect = 2e-05
Identities = 37/138 (26%), Positives = 67/138 (48%), Gaps = 5/138 (3%)
Query: 737 LLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRT-RVVSGFIFLRLIC 795
LL + D+ L+I +S + P +RY+ L+ K+P+ +VV ++ R +
Sbjct: 514 LLAMTDKFLLAITSSVDQIPYGMRYVAKVLKATLAEKFPDATDSEVYKVVGNLLYYRFLN 573
Query: 796 PALVEPRAWTLVQRAPP---PHAQRSLL-MVAKCLQNLANLVEFGAKEPYMEVVNPFILK 851
PA+V P A+ +V A QR L VA+ LQ+ A F + ++ V+N ++ +
Sbjct: 574 PAVVAPDAFDIVAMAAGGALAAPQRHALGAVAQLLQHAAAGKAFSGQSQHLRVLNDYLEE 633
Query: 852 NKERMVVFLDQLSNVPDP 869
+ F+ + VP+P
Sbjct: 634 THLKFRKFIHRACQVPEP 651
>AC020596-1|AAY14940.1| 176|Homo sapiens unknown protein.
Length = 176
Score = 51.2 bits (117), Expect = 2e-05
Identities = 25/71 (35%), Positives = 46/71 (64%), Gaps = 3/71 (4%)
Query: 67 YHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYIG 126
+HG + R +++ L A +GSYL+RES R+PG+Y L+ + +FR+ G +++G
Sbjct: 43 FHGMISREAADQLLIVA--EGSYLIRESQRQPGTYTLALRFGSQTRNFRL-YYDGKHFVG 99
Query: 127 GRQFDSLTELV 137
++F+S+ +LV
Sbjct: 100 EKRFESIHDLV 110
Score = 44.0 bits (99), Expect = 0.003
Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Query: 236 FHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGG 295
FH ++ EA D L+ GS+L+R S PG Y+L +Q + FR+ G ++ +G
Sbjct: 43 FHGMISR-EAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDG-KHFVGE 100
Query: 296 RTFECLDAVI 305
+ FE + ++
Sbjct: 101 KRFESIHDLV 110
>AB105103-1|BAC78211.1| 1631|Homo sapiens IQGAP3 protein.
Length = 1631
Score = 51.2 bits (117), Expect = 2e-05
Identities = 37/138 (26%), Positives = 67/138 (48%), Gaps = 5/138 (3%)
Query: 737 LLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRT-RVVSGFIFLRLIC 795
LL + D+ L+I +S + P +RY+ L+ K+P+ +VV ++ R +
Sbjct: 1122 LLAMTDKFLLAITSSVDQIPYGMRYVAKVLKATLAEKFPDATDSEVYKVVGNLLYYRFLN 1181
Query: 796 PALVEPRAWTLVQRAPP---PHAQRSLL-MVAKCLQNLANLVEFGAKEPYMEVVNPFILK 851
PA+V P A+ +V A QR L VA+ LQ+ A F + ++ V+N ++ +
Sbjct: 1182 PAVVAPDAFDIVAMAAGGALAAPQRHALGAVAQLLQHAAAGKAFSGQSQHLRVLNDYLEE 1241
Query: 852 NKERMVVFLDQLSNVPDP 869
+ F+ + VP+P
Sbjct: 1242 THLKFRKFIHRACQVPEP 1259
Score = 32.7 bits (71), Expect = 6.2
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 170 AILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDP 229
+++P K+ D ++L +Q + F H D + WL AH G F E + D P
Sbjct: 78 SVVPLKKIYDVEQLRYQATGLHFRHTDNINFWLSAIAH-IGLPSTFFPETTDIYDKKNMP 136
Query: 230 NTVF 233
V+
Sbjct: 137 RVVY 140
>U15528-2|AAA82880.1| 595|Homo sapiens protein tyrosine phosphatase
1C protein.
Length = 595
Score = 50.8 bits (116), Expect = 2e-05
Identities = 31/87 (35%), Positives = 45/87 (51%), Gaps = 10/87 (11%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLG---RTG------I 111
P WYHG + +E L A + ++LVRES +PG + LS L + G +
Sbjct: 105 PTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFELSVLSDQPKAGPGSPLRV 164
Query: 112 NHFRITAVCGDYYIGGRQ-FDSLTELV 137
H ++ G Y +GG + FDSLT+LV
Sbjct: 165 THIKVMCEGGRYTVGGLETFDSLTDLV 191
Score = 50.0 bits (114), Expect = 4e-05
Identities = 28/80 (35%), Positives = 42/80 (52%), Gaps = 2/80 (2%)
Query: 235 WFHPNCTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRY-L 292
WF + + +A +L G GSFL RPS + GD+SL + +Q+ RI+ G Y L
Sbjct: 4 WFLRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDL 63
Query: 293 MGGRTFECLDAVINRYRKEQ 312
GG F L ++ Y ++Q
Sbjct: 64 YGGEKFATLTELVEYYTQQQ 83
Score = 44.4 bits (100), Expect = 0.002
Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY- 124
W+ L +E L GS+L R S + G + LS + H RI GD+Y
Sbjct: 4 WFLRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQN-SGDFYD 62
Query: 125 -IGGRQFDSLTELVGFYSHCSDLLK 148
GG +F +LTELV +Y+ +L+
Sbjct: 63 LYGGEKFATLTELVEYYTQQQGVLQ 87
Score = 39.9 bits (89), Expect = 0.041
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 12/99 (12%)
Query: 228 DPNTVFSWFHPNCTKSEAVDML-VKAGPGSFLVRPSDNSPGDYSLFFHINN--------- 277
DP T W+H + + +A +L K P +FLVR S + PGD+ L +
Sbjct: 104 DP-TSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFELSVLSDQPKAGPGSPL 162
Query: 278 QIQRFRIEKKGVRYLMGG-RTFECLDAVINRYRKEQIVE 315
++ ++ +G RY +GG TF+ L ++ ++K I E
Sbjct: 163 RVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEE 201
>U15528-1|AAA82879.1| 556|Homo sapiens protein tyrosine phosphatase
1C protein.
Length = 556
Score = 50.8 bits (116), Expect = 2e-05
Identities = 31/87 (35%), Positives = 45/87 (51%), Gaps = 10/87 (11%)
Query: 61 PPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLG---RTG------I 111
P WYHG + +E L A + ++LVRES +PG + LS L + G +
Sbjct: 66 PTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFELSVLSDQPKAGPGSPLRV 125
Query: 112 NHFRITAVCGDYYIGGRQ-FDSLTELV 137
H ++ G Y +GG + FDSLT+LV
Sbjct: 126 THIKVMCEGGRYTVGGLETFDSLTDLV 152
Score = 39.9 bits (89), Expect = 0.041
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 12/99 (12%)
Query: 228 DPNTVFSWFHPNCTKSEAVDML-VKAGPGSFLVRPSDNSPGDYSLFFHINN--------- 277
DP T W+H + + +A +L K P +FLVR S + PGD+ L +
Sbjct: 65 DP-TSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFELSVLSDQPKAGPGSPL 123
Query: 278 QIQRFRIEKKGVRYLMGG-RTFECLDAVINRYRKEQIVE 315
++ ++ +G RY +GG TF+ L ++ ++K I E
Sbjct: 124 RVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEE 162
>U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinemia
tyrosine kinase protein.
Length = 657
Score = 50.8 bits (116), Expect = 2e-05
Identities = 32/110 (29%), Positives = 59/110 (53%), Gaps = 9/110 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVED 222
++ K+VVA+ Y M + ++L +KGD +F+ + W W + G++G I V +
Sbjct: 214 SELKKVVALYDYMPM-NANDLQLRKGDEYFILEESNLPW-WRARDKNGQEGYIPSNYVTE 271
Query: 223 LDPSIDPNTVFSWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSL 271
+ SI+ W+ + T+S+A +L + G G F+VR S + G Y++
Sbjct: 272 AEDSIE-----MWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKA-GKYTV 315
Score = 39.9 bits (89), Expect = 0.041
Identities = 25/87 (28%), Positives = 44/87 (50%), Gaps = 9/87 (10%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGR-TG-----INHFRITAV 119
WY + R +E+ L K+G ++VR+S K G Y +S + TG I H+ + +
Sbjct: 279 WYSKHMTRSQAEQLLKQEGKEGGFIVRDSS-KAGKYTVSVFAKSTGDPQGVIRHYVVCST 337
Query: 120 -CGDYYIGGRQ-FDSLTELVGFYSHCS 144
YY+ + F ++ EL+ ++ H S
Sbjct: 338 PQSQYYLAEKHLFSTIPELINYHQHNS 364
>M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein.
Length = 491
Score = 50.8 bits (116), Expect = 2e-05
Identities = 43/153 (28%), Positives = 76/153 (49%), Gaps = 15/153 (9%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
VVA+ PY + D+L+F+KG+ V + G+ W + T ++G I V L+ ++
Sbjct: 47 VVALYPYDGI-HPDDLSFKKGEKMKVLEEHGEWWK-AKSLLTKKEGFIPSNYVAKLN-TL 103
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSL----FFHINNQ-IQ 280
+ WF + T+ +A L+ G G+FL+R S+ G +SL F ++ I+
Sbjct: 104 ETE---EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIK 160
Query: 281 RFRIEK--KGVRYLMGGRTFECLDAVINRYRKE 311
++I G Y+ TF C+ +I Y+K+
Sbjct: 161 HYKIRSLDNGGYYISPRITFPCISDMIKHYQKQ 193
Score = 38.3 bits (85), Expect = 0.13
Identities = 28/93 (30%), Positives = 49/93 (52%), Gaps = 8/93 (8%)
Query: 65 EWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSY-----LGRTGINHFRITA 118
EW+ + R +E +L A + G++L+RES+ GS+ LS + I H++I +
Sbjct: 107 EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIRS 166
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSDLLKR 149
+ G YYI R F +++++ Y +D L R
Sbjct: 167 LDNGGYYISPRITFPCISDMIKHYQKQADGLCR 199
>M16038-1|AAA59540.1| 512|Homo sapiens LYN protein.
Length = 512
Score = 50.8 bits (116), Expect = 2e-05
Identities = 43/153 (28%), Positives = 76/153 (49%), Gaps = 15/153 (9%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
VVA+ PY + D+L+F+KG+ V + G+ W + T ++G I V L+ ++
Sbjct: 68 VVALYPYDGI-HPDDLSFKKGEKMKVLEEHGEWWK-AKSLLTKKEGFIPSNYVAKLN-TL 124
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSL----FFHINNQ-IQ 280
+ WF + T+ +A L+ G G+FL+R S+ G +SL F ++ I+
Sbjct: 125 ETE---EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIK 181
Query: 281 RFRIEK--KGVRYLMGGRTFECLDAVINRYRKE 311
++I G Y+ TF C+ +I Y+K+
Sbjct: 182 HYKIRSLDNGGYYISPRITFPCISDMIKHYQKQ 214
Score = 38.3 bits (85), Expect = 0.13
Identities = 28/93 (30%), Positives = 49/93 (52%), Gaps = 8/93 (8%)
Query: 65 EWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSY-----LGRTGINHFRITA 118
EW+ + R +E +L A + G++L+RES+ GS+ LS + I H++I +
Sbjct: 128 EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIRS 187
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSDLLKR 149
+ G YYI R F +++++ Y +D L R
Sbjct: 188 LDNGGYYISPRITFPCISDMIKHYQKQADGLCR 220
>M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like
kinase (slk) mRNA, complete cds. ).
Length = 537
Score = 50.8 bits (116), Expect = 2e-05
Identities = 32/85 (37%), Positives = 50/85 (58%), Gaps = 8/85 (9%)
Query: 65 EWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSY-----LGRTGINHFRITA 118
EWY G+L R +E +L + + +G++L+RES+ GSY LS + + H++I
Sbjct: 148 EWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGSYSLSIRDWDDMKGDHVKHYKIRK 207
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYS 141
+ G YYI R QF++L +LV YS
Sbjct: 208 LDNGGYYITTRAQFETLQQLVQHYS 232
Score = 48.8 bits (111), Expect = 9e-05
Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 14/149 (9%)
Query: 169 VAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
VA+ Y + D+L+F KG+ F + N W + TGE G I V +D SI
Sbjct: 88 VALYDYEARTE-DDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVD-SIQ 145
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFH-----INNQIQR 281
W+ + +A L+ G G+FL+R S+ + G YSL + ++
Sbjct: 146 AE---EWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGSYSLSIRDWDDMKGDHVKH 202
Query: 282 FRIEK--KGVRYLMGGRTFECLDAVINRY 308
++I K G Y+ FE L ++ Y
Sbjct: 203 YKIRKLDNGGYYITTRAQFETLQQLVQHY 231
>BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein.
Length = 512
Score = 50.8 bits (116), Expect = 2e-05
Identities = 43/153 (28%), Positives = 76/153 (49%), Gaps = 15/153 (9%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
VVA+ PY + D+L+F+KG+ V + G+ W + T ++G I V L+ ++
Sbjct: 68 VVALYPYDGI-HPDDLSFKKGEKMKVLEEHGEWWK-AKSLLTKKEGFIPSNYVAKLN-TL 124
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSL----FFHINNQ-IQ 280
+ WF + T+ +A L+ G G+FL+R S+ G +SL F ++ I+
Sbjct: 125 ETE---EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIK 181
Query: 281 RFRIEK--KGVRYLMGGRTFECLDAVINRYRKE 311
++I G Y+ TF C+ +I Y+K+
Sbjct: 182 HYKIRSLDNGGYYISPRITFPCISDMIKHYQKQ 214
Score = 38.3 bits (85), Expect = 0.13
Identities = 28/93 (30%), Positives = 49/93 (52%), Gaps = 8/93 (8%)
Query: 65 EWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSY-----LGRTGINHFRITA 118
EW+ + R +E +L A + G++L+RES+ GS+ LS + I H++I +
Sbjct: 128 EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIRS 187
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSDLLKR 149
+ G YYI R F +++++ Y +D L R
Sbjct: 188 LDNGGYYISPRITFPCISDMIKHYQKQADGLCR 220
>BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein.
Length = 512
Score = 50.8 bits (116), Expect = 2e-05
Identities = 43/153 (28%), Positives = 76/153 (49%), Gaps = 15/153 (9%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
VVA+ PY + D+L+F+KG+ V + G+ W + T ++G I V L+ ++
Sbjct: 68 VVALYPYDGI-HPDDLSFKKGEKMKVLEEHGEWWK-AKSLLTKKEGFIPSNYVAKLN-TL 124
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSL----FFHINNQ-IQ 280
+ WF + T+ +A L+ G G+FL+R S+ G +SL F ++ I+
Sbjct: 125 ETE---EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIK 181
Query: 281 RFRIEK--KGVRYLMGGRTFECLDAVINRYRKE 311
++I G Y+ TF C+ +I Y+K+
Sbjct: 182 HYKIRSLDNGGYYISPRITFPCISDMIKHYQKQ 214
Score = 38.3 bits (85), Expect = 0.13
Identities = 28/93 (30%), Positives = 49/93 (52%), Gaps = 8/93 (8%)
Query: 65 EWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSY-----LGRTGINHFRITA 118
EW+ + R +E +L A + G++L+RES+ GS+ LS + I H++I +
Sbjct: 128 EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIRS 187
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSDLLKR 149
+ G YYI R F +++++ Y +D L R
Sbjct: 188 LDNGGYYISPRITFPCISDMIKHYQKQADGLCR 220
>BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral related oncogene homolog protein.
Length = 512
Score = 50.8 bits (116), Expect = 2e-05
Identities = 43/153 (28%), Positives = 76/153 (49%), Gaps = 15/153 (9%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
VVA+ PY + D+L+F+KG+ V + G+ W + T ++G I V L+ ++
Sbjct: 68 VVALYPYDGI-HPDDLSFKKGEKMKVLEEHGEWWK-AKSLLTKKEGFIPSNYVAKLN-TL 124
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSL----FFHINNQ-IQ 280
+ WF + T+ +A L+ G G+FL+R S+ G +SL F ++ I+
Sbjct: 125 ETE---EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIK 181
Query: 281 RFRIEK--KGVRYLMGGRTFECLDAVINRYRKE 311
++I G Y+ TF C+ +I Y+K+
Sbjct: 182 HYKIRSLDNGGYYISPRITFPCISDMIKHYQKQ 214
Score = 38.3 bits (85), Expect = 0.13
Identities = 28/93 (30%), Positives = 49/93 (52%), Gaps = 8/93 (8%)
Query: 65 EWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSY-----LGRTGINHFRITA 118
EW+ + R +E +L A + G++L+RES+ GS+ LS + I H++I +
Sbjct: 128 EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIRS 187
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSDLLKR 149
+ G YYI R F +++++ Y +D L R
Sbjct: 188 LDNGGYYISPRITFPCISDMIKHYQKQADGLCR 220
>BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral related oncogene homolog protein.
Length = 512
Score = 50.8 bits (116), Expect = 2e-05
Identities = 43/153 (28%), Positives = 76/153 (49%), Gaps = 15/153 (9%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
VVA+ PY + D+L+F+KG+ V + G+ W + T ++G I V L+ ++
Sbjct: 68 VVALYPYDGI-HPDDLSFKKGEKMKVLEEHGEWWK-AKSLLTKKEGFIPSNYVAKLN-TL 124
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSL----FFHINNQ-IQ 280
+ WF + T+ +A L+ G G+FL+R S+ G +SL F ++ I+
Sbjct: 125 ETE---EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIK 181
Query: 281 RFRIEK--KGVRYLMGGRTFECLDAVINRYRKE 311
++I G Y+ TF C+ +I Y+K+
Sbjct: 182 HYKIRSLDNGGYYISPRITFPCISDMIKHYQKQ 214
Score = 38.3 bits (85), Expect = 0.13
Identities = 28/93 (30%), Positives = 49/93 (52%), Gaps = 8/93 (8%)
Query: 65 EWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSY-----LGRTGINHFRITA 118
EW+ + R +E +L A + G++L+RES+ GS+ LS + I H++I +
Sbjct: 128 EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIRS 187
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSDLLKR 149
+ G YYI R F +++++ Y +D L R
Sbjct: 188 LDNGGYYISPRITFPCISDMIKHYQKQADGLCR 220
>BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein.
Length = 582
Score = 50.8 bits (116), Expect = 2e-05
Identities = 43/153 (28%), Positives = 76/153 (49%), Gaps = 15/153 (9%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
VVA+ PY + D+L+F+KG+ V + G+ W + T ++G I V L+ ++
Sbjct: 138 VVALYPYDGI-HPDDLSFKKGEKMKVLEEHGEWWK-AKSLLTKKEGFIPSNYVAKLN-TL 194
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSL----FFHINNQ-IQ 280
+ WF + T+ +A L+ G G+FL+R S+ G +SL F ++ I+
Sbjct: 195 ETE---EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIK 251
Query: 281 RFRIEK--KGVRYLMGGRTFECLDAVINRYRKE 311
++I G Y+ TF C+ +I Y+K+
Sbjct: 252 HYKIRSLDNGGYYISPRITFPCISDMIKHYQKQ 284
Score = 38.3 bits (85), Expect = 0.13
Identities = 28/93 (30%), Positives = 49/93 (52%), Gaps = 8/93 (8%)
Query: 65 EWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSY-----LGRTGINHFRITA 118
EW+ + R +E +L A + G++L+RES+ GS+ LS + I H++I +
Sbjct: 198 EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIRS 257
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSDLLKR 149
+ G YYI R F +++++ Y +D L R
Sbjct: 258 LDNGGYYISPRITFPCISDMIKHYQKQADGLCR 290
>BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein.
Length = 582
Score = 50.8 bits (116), Expect = 2e-05
Identities = 43/153 (28%), Positives = 76/153 (49%), Gaps = 15/153 (9%)
Query: 168 VVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSI 227
VVA+ PY + D+L+F+KG+ V + G+ W + T ++G I V L+ ++
Sbjct: 138 VVALYPYDGI-HPDDLSFKKGEKMKVLEEHGEWWK-AKSLLTKKEGFIPSNYVAKLN-TL 194
Query: 228 DPNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSL----FFHINNQ-IQ 280
+ WF + T+ +A L+ G G+FL+R S+ G +SL F ++ I+
Sbjct: 195 ETE---EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIK 251
Query: 281 RFRIEK--KGVRYLMGGRTFECLDAVINRYRKE 311
++I G Y+ TF C+ +I Y+K+
Sbjct: 252 HYKIRSLDNGGYYISPRITFPCISDMIKHYQKQ 284
Score = 38.3 bits (85), Expect = 0.13
Identities = 28/93 (30%), Positives = 49/93 (52%), Gaps = 8/93 (8%)
Query: 65 EWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSY-----LGRTGINHFRITA 118
EW+ + R +E +L A + G++L+RES+ GS+ LS + I H++I +
Sbjct: 198 EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIRS 257
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYSHCSDLLKR 149
+ G YYI R F +++++ Y +D L R
Sbjct: 258 LDNGGYYISPRITFPCISDMIKHYQKQADGLCR 290
>X75342-1|CAA53091.1| 596|Homo sapiens Shb protein.
Length = 596
Score = 50.4 bits (115), Expect = 3e-05
Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Query: 53 GERQAVLAPPETE-WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGI 111
GER P E + WYHG + R +E L K+ SYLVR S Y LS G
Sbjct: 483 GERVDPAVPLEKQIWYHGAISRGDAENLL-RLCKECSYLVRNSQTSKHDYPLSLRSNQGF 541
Query: 112 NHFRITAVCGDYYIGGRQ--FDSLTELVGFYS 141
H ++ Y +G FDS+ E++ +Y+
Sbjct: 542 MHMKLAKTKEKYVLGQNSPPFDSVPEVIHYYT 573
Score = 41.9 bits (94), Expect = 0.010
Identities = 26/97 (26%), Positives = 47/97 (48%), Gaps = 3/97 (3%)
Query: 219 LVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQ 278
L E +DP++ P W+H ++ +A ++L S+LVR S S DY L N
Sbjct: 482 LGERVDPAV-PLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYPLSLRSNQG 540
Query: 279 IQRFRIEKKGVRYLMGGRT--FECLDAVINRYRKEQI 313
++ K +Y++G + F+ + VI+ Y ++
Sbjct: 541 FMHMKLAKTKEKYVLGQNSPPFDSVPEVIHYYTTRKL 577
>U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 50.4 bits (115), Expect = 3e-05
Identities = 33/96 (34%), Positives = 53/96 (55%), Gaps = 10/96 (10%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLS-YLG-----RTGINHFRITA 118
EWYH + R +E L SK+G+++VR+S R GSY +S ++G I H++I
Sbjct: 149 EWYHRNITRNQAEHLLRQESKEGAFIVRDS-RHLGSYTISVFMGARRSTEAAIKHYQIKK 207
Query: 119 -VCGDYYIGGRQ-FDSLTELVGFYSH-CSDLLKRER 151
G +Y+ R F S+ EL+ ++ H + L+ R R
Sbjct: 208 NDSGQWYVAERHAFQSIPELIWYHQHNAAGLMTRLR 243
Score = 35.9 bits (79), Expect = 0.67
Identities = 22/90 (24%), Positives = 44/90 (48%), Gaps = 5/90 (5%)
Query: 183 LTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNCTK 242
L ++ + + + W W R G +G+I V + I ++ W+H N T+
Sbjct: 101 LALRRAEEYLILEKYNPHW-WKARDRLGNEGLIPSNYVTE--NKITNLEIYEWYHRNITR 157
Query: 243 SEAVDML-VKAGPGSFLVRPSDNSPGDYSL 271
++A +L ++ G+F+VR S + G Y++
Sbjct: 158 NQAEHLLRQESKEGAFIVRDSRHL-GSYTI 186
>M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine
kinase arg gene mRNA. ).
Length = 1182
Score = 50.4 bits (115), Expect = 3e-05
Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDYY 124
WYHG + R ++ E L ++ GS+LVRES+ PG +S + H+RI T G Y
Sbjct: 173 WYHGPVSR-SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVY 231
Query: 125 IGGR-QFDSLTELVGFYSHCSD 145
+ +F +L ELV +S +D
Sbjct: 232 VTAESRFSTLAELVHHHSTVAD 253
Score = 42.7 bits (96), Expect = 0.006
Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
+D VA+ + D + L+ KG+ V +N G+ W QG + +
Sbjct: 107 SDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNQNGE---WSEVRSKNGQGWVPSNYI 162
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H ++S A +L GSFLVR S++SPG S+ ++
Sbjct: 163 TPVN-SLEKH---SWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVY 218
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 219 HYRINTTADGKVYVTAESRFSTLAELVHHH 248
>L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 50.4 bits (115), Expect = 3e-05
Identities = 33/96 (34%), Positives = 53/96 (55%), Gaps = 10/96 (10%)
Query: 65 EWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLS-YLG-----RTGINHFRITA 118
EWYH + R +E L SK+G+++VR+S R GSY +S ++G I H++I
Sbjct: 149 EWYHRNITRNQAEHLLRQESKEGAFIVRDS-RHLGSYTISVFMGARRSTEAAIKHYQIKK 207
Query: 119 -VCGDYYIGGRQ-FDSLTELVGFYSH-CSDLLKRER 151
G +Y+ R F S+ EL+ ++ H + L+ R R
Sbjct: 208 NDSGQWYVAERHAFQSIPELIWYHQHNAAGLMTRLR 243
Score = 35.9 bits (79), Expect = 0.67
Identities = 22/90 (24%), Positives = 44/90 (48%), Gaps = 5/90 (5%)
Query: 183 LTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNCTK 242
L ++ + + + W W R G +G+I V + I ++ W+H N T+
Sbjct: 101 LALRRAEEYLILEKYNPHW-WKARDRLGNEGLIPSNYVTE--NKITNLEIYEWYHRNITR 157
Query: 243 SEAVDML-VKAGPGSFLVRPSDNSPGDYSL 271
++A +L ++ G+F+VR S + G Y++
Sbjct: 158 NQAEHLLRQESKEGAFIVRDSRHL-GSYTI 186
>DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 50.4 bits (115), Expect = 3e-05
Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDYY 124
WYHG + R ++ E L ++ GS+LVRES+ PG +S + H+RI T G Y
Sbjct: 173 WYHGPVSR-SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVY 231
Query: 125 IGGR-QFDSLTELVGFYSHCSD 145
+ +F +L ELV +S +D
Sbjct: 232 VTAESRFSTLAELVHHHSTVAD 253
Score = 42.7 bits (96), Expect = 0.006
Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
+D VA+ + D + L+ KG+ V +N G+ W QG + +
Sbjct: 107 SDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNQNGE---WSEVRSKNGQGWVPSNYI 162
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H ++S A +L GSFLVR S++SPG S+ ++
Sbjct: 163 TPVN-SLEKH---SWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVY 218
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 219 HYRINTTADGKVYVTAESRFSTLAELVHHH 248
>BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein
protein.
Length = 1092
Score = 50.4 bits (115), Expect = 3e-05
Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDYY 124
WYHG + R ++ E L ++ GS+LVRES+ PG +S + H+RI T G Y
Sbjct: 186 WYHGPVSR-SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVY 244
Query: 125 IGGR-QFDSLTELVGFYSHCSD 145
+ +F +L ELV +S +D
Sbjct: 245 VTAESRFSTLAELVHHHSTVAD 266
Score = 42.7 bits (96), Expect = 0.006
Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
+D VA+ + D + L+ KG+ V +N G+ W QG + +
Sbjct: 120 SDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNQNGE---WSEVRSKNGQGWVPSNYI 175
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H ++S A +L GSFLVR S++SPG S+ ++
Sbjct: 176 TPVN-SLEKH---SWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVY 231
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 232 HYRINTTADGKVYVTAESRFSTLAELVHHH 261
>BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein.
Length = 1167
Score = 50.4 bits (115), Expect = 3e-05
Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDYY 124
WYHG + R ++ E L ++ GS+LVRES+ PG +S + H+RI T G Y
Sbjct: 158 WYHGPVSR-SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVY 216
Query: 125 IGGR-QFDSLTELVGFYSHCSD 145
+ +F +L ELV +S +D
Sbjct: 217 VTAESRFSTLAELVHHHSTVAD 238
Score = 42.7 bits (96), Expect = 0.006
Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
+D VA+ + D + L+ KG+ V +N G+ W QG + +
Sbjct: 92 SDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNQNGE---WSEVRSKNGQGWVPSNYI 147
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H ++S A +L GSFLVR S++SPG S+ ++
Sbjct: 148 TPVN-SLEKH---SWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVY 203
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 204 HYRINTTADGKVYVTAESRFSTLAELVHHH 233
>BC018646-1|AAH18646.1| 1265|Homo sapiens PLCG2 protein protein.
Length = 1265
Score = 50.4 bits (115), Expect = 3e-05
Identities = 38/165 (23%), Positives = 78/165 (47%), Gaps = 9/165 (5%)
Query: 216 FRELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVK-AGPGSFLVRPSDNSPGDYSLFFH 274
F + D P+ +P+ W++ + ++ EA DML++ G+FL+R + S Y++ F
Sbjct: 627 FELRLTDPVPNPNPHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGS-DSYAITFR 685
Query: 275 INNQIQRFRIEKKGVRYLMG-GRTFECLDAVINRYRKEQIVEGHTLGQPL---IAEGHTI 330
+++ RI + G +++G FE L +++ Y K + L P+ + E + +
Sbjct: 686 ARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHSLYRKMRLRYPVTPELLERYNM 745
Query: 331 EPQQSTTGAAAEKIYATLRECRDQIGLKKTKGIKHYGYLNKKSDK 375
E + + ++Y E + + K + Y Y K+SD+
Sbjct: 746 E-RDINSLYDVSRMYVDPSEINPSMPQRTVKAL--YDYKAKRSDE 787
Score = 46.8 bits (106), Expect = 4e-04
Identities = 29/94 (30%), Positives = 50/94 (53%), Gaps = 4/94 (4%)
Query: 61 PPETE-WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAV 119
P E++ WY+ L R +E+ L + G++L+R+ + SY +++ R + H RI
Sbjct: 640 PHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGS-DSYAITFRARGKVKHCRINRD 698
Query: 120 CGDYYIG-GRQFDSLTELVGFYSHCSDLLKRERL 152
+ +G F+SL ELV +Y S L ++ RL
Sbjct: 699 GRHFVLGTSAYFESLVELVSYYEKHS-LYRKMRL 731
Score = 41.5 bits (93), Expect = 0.013
Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 13/108 (12%)
Query: 218 ELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVK-------AGPGSFLVRPSDNSPGDYS 270
E+ +D+ P+ + + WFH K + + L++ G+FLVR S+ P DY+
Sbjct: 516 EVPQDIPPT-ELHFGEKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYT 574
Query: 271 LFFHINNQIQRFRIEK--KG---VRYLMGGRTFECLDAVINRYRKEQI 313
L F + ++Q RI +G YL TF + A+I YR+ +
Sbjct: 575 LSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHL 622
Score = 40.7 bits (91), Expect = 0.023
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 6/58 (10%)
Query: 65 EWYHGRLDRYTSEERLW------AASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI 116
+W+H ++++ TS E+L K G++LVRES+ P Y LS+ + H RI
Sbjct: 531 KWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRI 588
>BC014561-1|AAH14561.1| 1265|Homo sapiens PLCG2 protein protein.
Length = 1265
Score = 50.4 bits (115), Expect = 3e-05
Identities = 38/165 (23%), Positives = 78/165 (47%), Gaps = 9/165 (5%)
Query: 216 FRELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVK-AGPGSFLVRPSDNSPGDYSLFFH 274
F + D P+ +P+ W++ + ++ EA DML++ G+FL+R + S Y++ F
Sbjct: 627 FELRLTDPVPNPNPHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGS-DSYAITFR 685
Query: 275 INNQIQRFRIEKKGVRYLMG-GRTFECLDAVINRYRKEQIVEGHTLGQPL---IAEGHTI 330
+++ RI + G +++G FE L +++ Y K + L P+ + E + +
Sbjct: 686 ARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHSLYRKMRLRYPVTPELLERYNM 745
Query: 331 EPQQSTTGAAAEKIYATLRECRDQIGLKKTKGIKHYGYLNKKSDK 375
E + + ++Y E + + K + Y Y K+SD+
Sbjct: 746 E-RDINSLYDVSRMYVDPSEINPSMPQRTVKAL--YDYKAKRSDE 787
Score = 46.8 bits (106), Expect = 4e-04
Identities = 29/94 (30%), Positives = 50/94 (53%), Gaps = 4/94 (4%)
Query: 61 PPETE-WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAV 119
P E++ WY+ L R +E+ L + G++L+R+ + SY +++ R + H RI
Sbjct: 640 PHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGS-DSYAITFRARGKVKHCRINRD 698
Query: 120 CGDYYIG-GRQFDSLTELVGFYSHCSDLLKRERL 152
+ +G F+SL ELV +Y S L ++ RL
Sbjct: 699 GRHFVLGTSAYFESLVELVSYYEKHS-LYRKMRL 731
Score = 41.5 bits (93), Expect = 0.013
Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 13/108 (12%)
Query: 218 ELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVK-------AGPGSFLVRPSDNSPGDYS 270
E+ +D+ P+ + + WFH K + + L++ G+FLVR S+ P DY+
Sbjct: 516 EVPQDIPPT-ELHFGEKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYT 574
Query: 271 LFFHINNQIQRFRIEK--KG---VRYLMGGRTFECLDAVINRYRKEQI 313
L F + ++Q RI +G YL TF + A+I YR+ +
Sbjct: 575 LSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHL 622
Score = 40.7 bits (91), Expect = 0.023
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 6/58 (10%)
Query: 65 EWYHGRLDRYTSEERLW------AASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI 116
+W+H ++++ TS E+L K G++LVRES+ P Y LS+ + H RI
Sbjct: 531 KWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRI 588
>BC011772-1|AAH11772.1| 1265|Homo sapiens PLCG2 protein protein.
Length = 1265
Score = 50.4 bits (115), Expect = 3e-05
Identities = 38/165 (23%), Positives = 78/165 (47%), Gaps = 9/165 (5%)
Query: 216 FRELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVK-AGPGSFLVRPSDNSPGDYSLFFH 274
F + D P+ +P+ W++ + ++ EA DML++ G+FL+R + S Y++ F
Sbjct: 627 FELRLTDPVPNPNPHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGS-DSYAITFR 685
Query: 275 INNQIQRFRIEKKGVRYLMG-GRTFECLDAVINRYRKEQIVEGHTLGQPL---IAEGHTI 330
+++ RI + G +++G FE L +++ Y K + L P+ + E + +
Sbjct: 686 ARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHSLYRKMRLRYPVTPELLERYNM 745
Query: 331 EPQQSTTGAAAEKIYATLRECRDQIGLKKTKGIKHYGYLNKKSDK 375
E + + ++Y E + + K + Y Y K+SD+
Sbjct: 746 E-RDINSLYDVSRMYVDPSEINPSMPQRTVKAL--YDYKAKRSDE 787
Score = 46.8 bits (106), Expect = 4e-04
Identities = 29/94 (30%), Positives = 50/94 (53%), Gaps = 4/94 (4%)
Query: 61 PPETE-WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAV 119
P E++ WY+ L R +E+ L + G++L+R+ + SY +++ R + H RI
Sbjct: 640 PHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGS-DSYAITFRARGKVKHCRINRD 698
Query: 120 CGDYYIG-GRQFDSLTELVGFYSHCSDLLKRERL 152
+ +G F+SL ELV +Y S L ++ RL
Sbjct: 699 GRHFVLGTSAYFESLVELVSYYEKHS-LYRKMRL 731
Score = 41.5 bits (93), Expect = 0.013
Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 13/108 (12%)
Query: 218 ELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVK-------AGPGSFLVRPSDNSPGDYS 270
E+ +D+ P+ + + WFH K + + L++ G+FLVR S+ P DY+
Sbjct: 516 EVPQDIPPT-ELHFGEKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYT 574
Query: 271 LFFHINNQIQRFRIEK--KG---VRYLMGGRTFECLDAVINRYRKEQI 313
L F + ++Q RI +G YL TF + A+I YR+ +
Sbjct: 575 LSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHL 622
Score = 40.7 bits (91), Expect = 0.023
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 6/58 (10%)
Query: 65 EWYHGRLDRYTSEERLW------AASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI 116
+W+H ++++ TS E+L K G++LVRES+ P Y LS+ + H RI
Sbjct: 531 KWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRI 588
>BC007565-1|AAH07565.1| 1265|Homo sapiens PLCG2 protein protein.
Length = 1265
Score = 50.4 bits (115), Expect = 3e-05
Identities = 38/165 (23%), Positives = 78/165 (47%), Gaps = 9/165 (5%)
Query: 216 FRELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVK-AGPGSFLVRPSDNSPGDYSLFFH 274
F + D P+ +P+ W++ + ++ EA DML++ G+FL+R + S Y++ F
Sbjct: 627 FELRLTDPVPNPNPHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGS-DSYAITFR 685
Query: 275 INNQIQRFRIEKKGVRYLMG-GRTFECLDAVINRYRKEQIVEGHTLGQPL---IAEGHTI 330
+++ RI + G +++G FE L +++ Y K + L P+ + E + +
Sbjct: 686 ARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHSLYRKMRLRYPVTPELLERYNM 745
Query: 331 EPQQSTTGAAAEKIYATLRECRDQIGLKKTKGIKHYGYLNKKSDK 375
E + + ++Y E + + K + Y Y K+SD+
Sbjct: 746 E-RDINSLYDVSRMYVDPSEINPSMPQRTVKAL--YDYKAKRSDE 787
Score = 46.8 bits (106), Expect = 4e-04
Identities = 29/94 (30%), Positives = 50/94 (53%), Gaps = 4/94 (4%)
Query: 61 PPETE-WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAV 119
P E++ WY+ L R +E+ L + G++L+R+ + SY +++ R + H RI
Sbjct: 640 PHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGS-DSYAITFRARGKVKHCRINRD 698
Query: 120 CGDYYIG-GRQFDSLTELVGFYSHCSDLLKRERL 152
+ +G F+SL ELV +Y S L ++ RL
Sbjct: 699 GRHFVLGTSAYFESLVELVSYYEKHS-LYRKMRL 731
Score = 41.5 bits (93), Expect = 0.013
Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 13/108 (12%)
Query: 218 ELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVK-------AGPGSFLVRPSDNSPGDYS 270
E+ +D+ P+ + + WFH K + + L++ G+FLVR S+ P DY+
Sbjct: 516 EVPQDIPPT-ELHFGEKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYT 574
Query: 271 LFFHINNQIQRFRIEK--KG---VRYLMGGRTFECLDAVINRYRKEQI 313
L F + ++Q RI +G YL TF + A+I YR+ +
Sbjct: 575 LSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHL 622
Score = 40.7 bits (91), Expect = 0.023
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 6/58 (10%)
Query: 65 EWYHGRLDRYTSEERLW------AASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI 116
+W+H ++++ TS E+L K G++LVRES+ P Y LS+ + H RI
Sbjct: 531 KWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRI 588
>AL583849-1|CAH73120.1| 509|Homo sapiens Src homology 2 domain
containing adaptor protein B protein.
Length = 509
Score = 50.4 bits (115), Expect = 3e-05
Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Query: 53 GERQAVLAPPETE-WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGI 111
GER P E + WYHG + R +E L K+ SYLVR S Y LS G
Sbjct: 396 GERVDPAVPLEKQIWYHGAISRGDAENLL-RLCKECSYLVRNSQTSKHDYSLSLRSNQGF 454
Query: 112 NHFRITAVCGDYYIGGRQ--FDSLTELVGFYS 141
H ++ Y +G FDS+ E++ +Y+
Sbjct: 455 MHMKLAKTKEKYVLGQNSPPFDSVPEVIHYYT 486
Score = 44.0 bits (99), Expect = 0.003
Identities = 27/97 (27%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 219 LVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQ 278
L E +DP++ P W+H ++ +A ++L S+LVR S S DYSL N
Sbjct: 395 LGERVDPAV-PLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYSLSLRSNQG 453
Query: 279 IQRFRIEKKGVRYLMGGRT--FECLDAVINRYRKEQI 313
++ K +Y++G + F+ + VI+ Y ++
Sbjct: 454 FMHMKLAKTKEKYVLGQNSPPFDSVPEVIHYYTTRKL 490
>AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 50.4 bits (115), Expect = 3e-05
Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDYY 124
WYHG + R ++ E L ++ GS+LVRES+ PG +S + H+RI T G Y
Sbjct: 173 WYHGPVSR-SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVY 231
Query: 125 IGGR-QFDSLTELVGFYSHCSD 145
+ +F +L ELV +S +D
Sbjct: 232 VTAESRFSTLAELVHHHSTVAD 253
Score = 42.7 bits (96), Expect = 0.006
Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
+D VA+ + D + L+ KG+ V +N G+ W QG + +
Sbjct: 107 SDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNQNGE---WSEVRSKNGQGWVPSNYI 162
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H ++S A +L GSFLVR S++SPG S+ ++
Sbjct: 163 TPVN-SLEKH---SWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVY 218
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 219 HYRINTTADGKVYVTAESRFSTLAELVHHH 248
>AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 50.4 bits (115), Expect = 3e-05
Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDYY 124
WYHG + R ++ E L ++ GS+LVRES+ PG +S + H+RI T G Y
Sbjct: 158 WYHGPVSR-SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVY 216
Query: 125 IGGR-QFDSLTELVGFYSHCSD 145
+ +F +L ELV +S +D
Sbjct: 217 VTAESRFSTLAELVHHHSTVAD 238
Score = 42.7 bits (96), Expect = 0.006
Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
+D VA+ + D + L+ KG+ V +N G+ W QG + +
Sbjct: 92 SDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNQNGE---WSEVRSKNGQGWVPSNYI 147
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H ++S A +L GSFLVR S++SPG S+ ++
Sbjct: 148 TPVN-SLEKH---SWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVY 203
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 204 HYRINTTADGKVYVTAESRFSTLAELVHHH 233
>AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 50.4 bits (115), Expect = 3e-05
Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDYY 124
WYHG + R ++ E L ++ GS+LVRES+ PG +S + H+RI T G Y
Sbjct: 173 WYHGPVSR-SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVY 231
Query: 125 IGGR-QFDSLTELVGFYSHCSD 145
+ +F +L ELV +S +D
Sbjct: 232 VTAESRFSTLAELVHHHSTVAD 253
Score = 42.7 bits (96), Expect = 0.006
Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
+D VA+ + D + L+ KG+ V +N G+ W QG + +
Sbjct: 107 SDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNQNGE---WSEVRSKNGQGWVPSNYI 162
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H ++S A +L GSFLVR S++SPG S+ ++
Sbjct: 163 TPVN-SLEKH---SWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVY 218
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 219 HYRINTTADGKVYVTAESRFSTLAELVHHH 248
>AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 50.4 bits (115), Expect = 3e-05
Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDYY 124
WYHG + R ++ E L ++ GS+LVRES+ PG +S + H+RI T G Y
Sbjct: 158 WYHGPVSR-SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVY 216
Query: 125 IGGR-QFDSLTELVGFYSHCSD 145
+ +F +L ELV +S +D
Sbjct: 217 VTAESRFSTLAELVHHHSTVAD 238
Score = 42.7 bits (96), Expect = 0.006
Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
+D VA+ + D + L+ KG+ V +N G+ W QG + +
Sbjct: 92 SDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNQNGE---WSEVRSKNGQGWVPSNYI 147
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H ++S A +L GSFLVR S++SPG S+ ++
Sbjct: 148 TPVN-SLEKH---SWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVY 203
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 204 HYRINTTADGKVYVTAESRFSTLAELVHHH 233
>AL161448-1|CAH73192.1| 509|Homo sapiens Src homology 2 domain
containing adaptor protein B protein.
Length = 509
Score = 50.4 bits (115), Expect = 3e-05
Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Query: 53 GERQAVLAPPETE-WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGI 111
GER P E + WYHG + R +E L K+ SYLVR S Y LS G
Sbjct: 396 GERVDPAVPLEKQIWYHGAISRGDAENLL-RLCKECSYLVRNSQTSKHDYSLSLRSNQGF 454
Query: 112 NHFRITAVCGDYYIGGRQ--FDSLTELVGFYS 141
H ++ Y +G FDS+ E++ +Y+
Sbjct: 455 MHMKLAKTKEKYVLGQNSPPFDSVPEVIHYYT 486
Score = 44.0 bits (99), Expect = 0.003
Identities = 27/97 (27%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 219 LVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQ 278
L E +DP++ P W+H ++ +A ++L S+LVR S S DYSL N
Sbjct: 395 LGERVDPAV-PLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYSLSLRSNQG 453
Query: 279 IQRFRIEKKGVRYLMGGRT--FECLDAVINRYRKEQI 313
++ K +Y++G + F+ + VI+ Y ++
Sbjct: 454 FMHMKLAKTKEKYVLGQNSPPFDSVPEVIHYYTTRKL 490
>AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 50.4 bits (115), Expect = 3e-05
Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDYY 124
WYHG + R ++ E L ++ GS+LVRES+ PG +S + H+RI T G Y
Sbjct: 173 WYHGPVSR-SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVY 231
Query: 125 IGGR-QFDSLTELVGFYSHCSD 145
+ +F +L ELV +S +D
Sbjct: 232 VTAESRFSTLAELVHHHSTVAD 253
Score = 42.7 bits (96), Expect = 0.006
Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
+D VA+ + D + L+ KG+ V +N G+ W QG + +
Sbjct: 107 SDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNQNGE---WSEVRSKNGQGWVPSNYI 162
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H ++S A +L GSFLVR S++SPG S+ ++
Sbjct: 163 TPVN-SLEKH---SWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVY 218
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 219 HYRINTTADGKVYVTAESRFSTLAELVHHH 248
>AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 50.4 bits (115), Expect = 3e-05
Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-TAVCGDYY 124
WYHG + R ++ E L ++ GS+LVRES+ PG +S + H+RI T G Y
Sbjct: 158 WYHGPVSR-SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVY 216
Query: 125 IGGR-QFDSLTELVGFYSHCSD 145
+ +F +L ELV +S +D
Sbjct: 217 VTAESRFSTLAELVHHHSTVAD 238
Score = 42.7 bits (96), Expect = 0.006
Identities = 37/150 (24%), Positives = 67/150 (44%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
+D VA+ + D + L+ KG+ V +N G+ W QG + +
Sbjct: 92 SDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNQNGE---WSEVRSKNGQGWVPSNYI 147
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H ++S A +L GSFLVR S++SPG S+ ++
Sbjct: 148 TPVN-SLEKH---SWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVY 203
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 204 HYRINTTADGKVYVTAESRFSTLAELVHHH 233
>AL138752-4|CAI13876.1| 509|Homo sapiens Src homology 2 domain
containing adaptor protein B protein.
Length = 509
Score = 50.4 bits (115), Expect = 3e-05
Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Query: 53 GERQAVLAPPETE-WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGI 111
GER P E + WYHG + R +E L K+ SYLVR S Y LS G
Sbjct: 396 GERVDPAVPLEKQIWYHGAISRGDAENLL-RLCKECSYLVRNSQTSKHDYSLSLRSNQGF 454
Query: 112 NHFRITAVCGDYYIGGRQ--FDSLTELVGFYS 141
H ++ Y +G FDS+ E++ +Y+
Sbjct: 455 MHMKLAKTKEKYVLGQNSPPFDSVPEVIHYYT 486
Score = 44.0 bits (99), Expect = 0.003
Identities = 27/97 (27%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 219 LVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQ 278
L E +DP++ P W+H ++ +A ++L S+LVR S S DYSL N
Sbjct: 395 LGERVDPAV-PLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYSLSLRSNQG 453
Query: 279 IQRFRIEKKGVRYLMGGRT--FECLDAVINRYRKEQI 313
++ K +Y++G + F+ + VI+ Y ++
Sbjct: 454 FMHMKLAKTKEKYVLGQNSPPFDSVPEVIHYYTTRKL 490
>AB208914-1|BAD92151.1| 1278|Homo sapiens
1-phosphatidylinositol-4,5-bisphosphate
phosphodiesterase gamma 2 variant protein.
Length = 1278
Score = 50.4 bits (115), Expect = 3e-05
Identities = 38/165 (23%), Positives = 78/165 (47%), Gaps = 9/165 (5%)
Query: 216 FRELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVK-AGPGSFLVRPSDNSPGDYSLFFH 274
F + D P+ +P+ W++ + ++ EA DML++ G+FL+R + S Y++ F
Sbjct: 640 FELRLTDPVPNPNPHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGS-DSYAITFR 698
Query: 275 INNQIQRFRIEKKGVRYLMG-GRTFECLDAVINRYRKEQIVEGHTLGQPL---IAEGHTI 330
+++ RI + G +++G FE L +++ Y K + L P+ + E + +
Sbjct: 699 ARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHSLYRKMRLRYPVTPELLERYNM 758
Query: 331 EPQQSTTGAAAEKIYATLRECRDQIGLKKTKGIKHYGYLNKKSDK 375
E + + ++Y E + + K + Y Y K+SD+
Sbjct: 759 E-RDINSLYDVSRMYVDPSEINPSMPQRTVKAL--YDYKAKRSDE 800
Score = 46.8 bits (106), Expect = 4e-04
Identities = 29/94 (30%), Positives = 50/94 (53%), Gaps = 4/94 (4%)
Query: 61 PPETE-WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAV 119
P E++ WY+ L R +E+ L + G++L+R+ + SY +++ R + H RI
Sbjct: 653 PHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGS-DSYAITFRARGKVKHCRINRD 711
Query: 120 CGDYYIG-GRQFDSLTELVGFYSHCSDLLKRERL 152
+ +G F+SL ELV +Y S L ++ RL
Sbjct: 712 GRHFVLGTSAYFESLVELVSYYEKHS-LYRKMRL 744
Score = 41.5 bits (93), Expect = 0.013
Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 13/108 (12%)
Query: 218 ELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVK-------AGPGSFLVRPSDNSPGDYS 270
E+ +D+ P+ + + WFH K + + L++ G+FLVR S+ P DY+
Sbjct: 529 EVPQDIPPT-ELHFGEKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYT 587
Query: 271 LFFHINNQIQRFRIEK--KG---VRYLMGGRTFECLDAVINRYRKEQI 313
L F + ++Q RI +G YL TF + A+I YR+ +
Sbjct: 588 LSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHL 635
Score = 40.7 bits (91), Expect = 0.023
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 6/58 (10%)
Query: 65 EWYHGRLDRYTSEERLW------AASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI 116
+W+H ++++ TS E+L K G++LVRES+ P Y LS+ + H RI
Sbjct: 544 KWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRI 601
>M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein.
Length = 1130
Score = 50.0 bits (114), Expect = 4e-05
Identities = 34/84 (40%), Positives = 48/84 (57%), Gaps = 7/84 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPG--SYVLSYLGRTGINHFRI-TAVCGD 122
WYHG + R +E L ++ GS+LVRES+ P S L Y GR + H+RI TA G
Sbjct: 127 WYHGPVSRNAAEYPL-SSGINGSFLVRESESSPSQRSISLRYEGR--VYHYRINTASDGK 183
Query: 123 YYIGGR-QFDSLTELVGFYSHCSD 145
Y+ +F++L ELV +S +D
Sbjct: 184 LYVSSESRFNTLAELVHHHSTVAD 207
Score = 41.9 bits (94), Expect = 0.010
Identities = 37/150 (24%), Positives = 66/150 (44%), Gaps = 12/150 (8%)
Query: 163 NDKKRVVAILPYTKMPDTDELTFQKGDIFFV--HNDMGDGWLWVTAHRTGEQGMIFRELV 220
ND VA+ + D + L+ KG+ V +N G+ W A QG + +
Sbjct: 61 NDPNLFVALYDFVASGD-NTLSITKGEKLRVLGYNHNGE---WCEAQTKNGQGWVPSNYI 116
Query: 221 EDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQ 280
++ S++ + SW+H +++ A L GSFLVR S++SP S+ ++
Sbjct: 117 TPVN-SLEKH---SWYHGPVSRNAAEYPLSSGINGSFLVRESESSPSQRSISLRYEGRVY 172
Query: 281 RFRIE--KKGVRYLMGGRTFECLDAVINRY 308
+RI G Y+ F L +++ +
Sbjct: 173 HYRINTASDGKLYVSSESRFNTLAELVHHH 202
>Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 537
Score = 49.6 bits (113), Expect = 5e-05
Identities = 31/85 (36%), Positives = 50/85 (58%), Gaps = 8/85 (9%)
Query: 65 EWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSY-----LGRTGINHFRITA 118
EWY G+L R +E +L + + +G++L+RES+ G+Y LS + + H++I
Sbjct: 148 EWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRK 207
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYS 141
+ G YYI R QF++L +LV YS
Sbjct: 208 LDNGGYYITTRAQFETLQQLVQHYS 232
Score = 48.0 bits (109), Expect = 2e-04
Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 14/149 (9%)
Query: 169 VAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
VA+ Y + D+L+F KG+ F + N W + TGE G I V +D SI
Sbjct: 88 VALYDYEARTE-DDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVD-SIQ 145
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFH-----INNQIQR 281
W+ + +A L+ G G+FL+R S+ + G YSL + ++
Sbjct: 146 AE---EWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKH 202
Query: 282 FRIEK--KGVRYLMGGRTFECLDAVINRY 308
++I K G Y+ FE L ++ Y
Sbjct: 203 YKIRKLDNGGYYITTRAQFETLQQLVQHY 231
>Z33998-1|CAA83965.1| 505|Homo sapiens Protein-Tyrosine Kinase
protein.
Length = 505
Score = 49.6 bits (113), Expect = 5e-05
Identities = 48/156 (30%), Positives = 73/156 (46%), Gaps = 14/156 (8%)
Query: 164 DKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDL 223
DK VVA+ YT M D D L KG+ V GD WL + TG +G + V +
Sbjct: 59 DKHFVVALYDYTAMNDRD-LQMLKGEKLQVLKGTGDWWL-ARSLVTGREGYVPSNFVARV 116
Query: 224 DPSIDPNTVFSWFHPNCTKSEAVDMLVKA--GPGSFLVRPSDNSPGDYSLFF-HINNQ-- 278
+ S++ WF + + EA L+ GSFL+R S+ + G +SL + Q
Sbjct: 117 E-SLEMER---WFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTTQGE 172
Query: 279 -IQRFRIE--KKGVRYLMGGRTFECLDAVINRYRKE 311
I+ ++I +G Y+ TF L A++ Y K+
Sbjct: 173 LIKHYKIRCLDEGGYYISPRITFPSLQALVQHYSKK 208
Score = 41.9 bits (94), Expect = 0.010
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 7/87 (8%)
Query: 66 WYHGRLDRYTSEERLWAA-SKQGSYLVRESDRKPGSYVLSYLGRTG----INHFRITAVC 120
W+ R +E +L A +K GS+L+RES+ G++ LS T I H++I +
Sbjct: 124 WFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTTQGELIKHYKIRCLD 183
Query: 121 -GDYYIGGR-QFDSLTELVGFYSHCSD 145
G YYI R F SL LV YS D
Sbjct: 184 EGGYYISPRITFPSLQALVQHYSKKGD 210
>Y14385-1|CAA74743.1| 1258|Homo sapiens inositol polyphosphate
5-phosphatase protein.
Length = 1258
Score = 49.6 bits (113), Expect = 5e-05
Identities = 29/83 (34%), Positives = 45/83 (54%), Gaps = 7/83 (8%)
Query: 66 WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI-------TA 118
WYH L R +EE L A + GS+LVR+S+ G++ L L + ++ +RI A
Sbjct: 21 WYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCVLYQKHVHTYRILPDGEDFLA 80
Query: 119 VCGDYYIGGRQFDSLTELVGFYS 141
V + R+F +L EL+G Y+
Sbjct: 81 VQTSQGVPVRRFQTLGELIGLYA 103
Score = 41.1 bits (92), Expect = 0.018
Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 234 SWFHPNCTKSEAVDMLVKAG-PGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYL 292
SW+H + +++ A ++L +AG GSFLVR S++ G ++L + +RI G +L
Sbjct: 20 SWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCVLYQKHVHTYRILPDGEDFL 79
>X14034-1|CAA32194.1| 1252|Homo sapiens protein ( Human mRNA for
phospholipase C. ).
Length = 1252
Score = 49.6 bits (113), Expect = 5e-05
Identities = 29/113 (25%), Positives = 57/113 (50%), Gaps = 3/113 (2%)
Query: 216 FRELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVK-AGPGSFLVRPSDNSPGDYSLFFH 274
F + D P+ +P+ W++ + ++ EA DML++ G+FL+R + S Y++ F
Sbjct: 627 FELRLTDPVPNPNPHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGS-DSYAITFR 685
Query: 275 INNQIQRFRIEKKGVRYLMG-GRTFECLDAVINRYRKEQIVEGHTLGQPLIAE 326
+++ RI + G +++G FE L +++ Y K + L P+ E
Sbjct: 686 ARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHSLYRKMRLRYPVTPE 738
Score = 46.8 bits (106), Expect = 4e-04
Identities = 29/94 (30%), Positives = 50/94 (53%), Gaps = 4/94 (4%)
Query: 61 PPETE-WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAV 119
P E++ WY+ L R +E+ L + G++L+R+ + SY +++ R + H RI
Sbjct: 640 PHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGS-DSYAITFRARGKVKHCRINRD 698
Query: 120 CGDYYIG-GRQFDSLTELVGFYSHCSDLLKRERL 152
+ +G F+SL ELV +Y S L ++ RL
Sbjct: 699 GRHFVLGTSAYFESLVELVSYYEKHS-LYRKMRL 731
Score = 40.7 bits (91), Expect = 0.023
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 6/58 (10%)
Query: 65 EWYHGRLDRYTSEERLW------AASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI 116
+W+H ++++ TS E+L K G++LVRES+ P Y LS+ + H RI
Sbjct: 531 KWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRI 588
Score = 38.3 bits (85), Expect = 0.13
Identities = 30/108 (27%), Positives = 51/108 (47%), Gaps = 13/108 (12%)
Query: 218 ELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVK-------AGPGSFLVRPSDNSPGDYS 270
E+ +D+ P+ + + WFH K + + L++ G+FLVR S+ P DY+
Sbjct: 516 EVPQDIPPT-ELHFGEKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYT 574
Query: 271 LFFHINNQIQRFRIEK--KG---VRYLMGGRTFECLDAVINRYRKEQI 313
L F + ++Q RI +G YL F + A+I YR+ +
Sbjct: 575 LSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLRFRRMYALIQHYRETHL 622
>S76617-1|AAB33265.1| 505|Homo sapiens blk protein.
Length = 505
Score = 49.6 bits (113), Expect = 5e-05
Identities = 48/156 (30%), Positives = 73/156 (46%), Gaps = 14/156 (8%)
Query: 164 DKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDL 223
DK VVA+ YT M D D L KG+ V GD WL + TG +G + V +
Sbjct: 59 DKHFVVALYDYTAMNDRD-LQMLKGEKLQVLKGTGDWWL-ARSLVTGREGYVPSNFVARV 116
Query: 224 DPSIDPNTVFSWFHPNCTKSEAVDMLVKA--GPGSFLVRPSDNSPGDYSLFF-HINNQ-- 278
+ S++ WF + + EA L+ GSFL+R S+ + G +SL + Q
Sbjct: 117 E-SLEMER---WFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTTQGE 172
Query: 279 -IQRFRIE--KKGVRYLMGGRTFECLDAVINRYRKE 311
I+ ++I +G Y+ TF L A++ Y K+
Sbjct: 173 LIKHYKIRCLDEGGYYISPRITFPSLQALVQHYSKK 208
Score = 41.9 bits (94), Expect = 0.010
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 7/87 (8%)
Query: 66 WYHGRLDRYTSEERLWAA-SKQGSYLVRESDRKPGSYVLSYLGRTG----INHFRITAVC 120
W+ R +E +L A +K GS+L+RES+ G++ LS T I H++I +
Sbjct: 124 WFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTTQGELIKHYKIRCLD 183
Query: 121 -GDYYIGGR-QFDSLTELVGFYSHCSD 145
G YYI R F SL LV YS D
Sbjct: 184 EGGYYISPRITFPSLQALVQHYSKKGD 210
>M37238-1|AAA60112.1| 1252|Homo sapiens PLC1 protein.
Length = 1252
Score = 49.6 bits (113), Expect = 5e-05
Identities = 29/113 (25%), Positives = 57/113 (50%), Gaps = 3/113 (2%)
Query: 216 FRELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVK-AGPGSFLVRPSDNSPGDYSLFFH 274
F + D P+ +P+ W++ + ++ EA DML++ G+FL+R + S Y++ F
Sbjct: 627 FELRLTDPVPNPNPHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGS-DSYAITFR 685
Query: 275 INNQIQRFRIEKKGVRYLMG-GRTFECLDAVINRYRKEQIVEGHTLGQPLIAE 326
+++ RI + G +++G FE L +++ Y K + L P+ E
Sbjct: 686 ARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHSLYRKMRLRYPVTPE 738
Score = 46.8 bits (106), Expect = 4e-04
Identities = 29/94 (30%), Positives = 50/94 (53%), Gaps = 4/94 (4%)
Query: 61 PPETE-WYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAV 119
P E++ WY+ L R +E+ L + G++L+R+ + SY +++ R + H RI
Sbjct: 640 PHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGS-DSYAITFRARGKVKHCRINRD 698
Query: 120 CGDYYIG-GRQFDSLTELVGFYSHCSDLLKRERL 152
+ +G F+SL ELV +Y S L ++ RL
Sbjct: 699 GRHFVLGTSAYFESLVELVSYYEKHS-LYRKMRL 731
Score = 40.7 bits (91), Expect = 0.023
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 6/58 (10%)
Query: 65 EWYHGRLDRYTSEERLW------AASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRI 116
+W+H ++++ TS E+L K G++LVRES+ P Y LS+ + H RI
Sbjct: 531 KWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRI 588
Score = 38.3 bits (85), Expect = 0.13
Identities = 30/108 (27%), Positives = 51/108 (47%), Gaps = 13/108 (12%)
Query: 218 ELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVK-------AGPGSFLVRPSDNSPGDYS 270
E+ +D+ P+ + + WFH K + + L++ G+FLVR S+ P DY+
Sbjct: 516 EVPQDIPPT-ELHFGEKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYT 574
Query: 271 LFFHINNQIQRFRIEK--KG---VRYLMGGRTFECLDAVINRYRKEQI 313
L F + ++Q RI +G YL F + A+I YR+ +
Sbjct: 575 LSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLRFRRMYALIQHYRETHL 622
>M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-syn
protooncogene mRNA, complete cds. ).
Length = 537
Score = 49.6 bits (113), Expect = 5e-05
Identities = 31/85 (36%), Positives = 50/85 (58%), Gaps = 8/85 (9%)
Query: 65 EWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSY-----LGRTGINHFRITA 118
EWY G+L R +E +L + + +G++L+RES+ G+Y LS + + H++I
Sbjct: 148 EWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRK 207
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYS 141
+ G YYI R QF++L +LV YS
Sbjct: 208 LDNGGYYITTRAQFETLQQLVQHYS 232
Score = 48.0 bits (109), Expect = 2e-04
Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 14/149 (9%)
Query: 169 VAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
VA+ Y + D+L+F KG+ F + N W + TGE G I V +D SI
Sbjct: 88 VALYDYEARTE-DDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVD-SIQ 145
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFH-----INNQIQR 281
W+ + +A L+ G G+FL+R S+ + G YSL + ++
Sbjct: 146 AE---EWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKH 202
Query: 282 FRIEK--KGVRYLMGGRTFECLDAVINRY 308
++I K G Y+ FE L ++ Y
Sbjct: 203 YKIRKLDNGGYYITTRAQFETLQQLVQHY 231
>BC032496-1|AAH32496.1| 482|Homo sapiens FYN oncogene related to
SRC, FGR, YES protein.
Length = 482
Score = 49.6 bits (113), Expect = 5e-05
Identities = 31/85 (36%), Positives = 50/85 (58%), Gaps = 8/85 (9%)
Query: 65 EWYHGRLDRYTSEERLWA-ASKQGSYLVRESDRKPGSYVLSY-----LGRTGINHFRITA 118
EWY G+L R +E +L + + +G++L+RES+ G+Y LS + + H++I
Sbjct: 148 EWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRK 207
Query: 119 V-CGDYYIGGR-QFDSLTELVGFYS 141
+ G YYI R QF++L +LV YS
Sbjct: 208 LDNGGYYITTRAQFETLQQLVQHYS 232
Score = 48.0 bits (109), Expect = 2e-04
Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 14/149 (9%)
Query: 169 VAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSID 228
VA+ Y + D+L+F KG+ F + N W + TGE G I V +D SI
Sbjct: 88 VALYDYEARTE-DDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVD-SIQ 145
Query: 229 PNTVFSWFHPNCTKSEAVDMLVKAG--PGSFLVRPSDNSPGDYSLFFH-----INNQIQR 281
W+ + +A L+ G G+FL+R S+ + G YSL + ++
Sbjct: 146 AE---EWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKH 202
Query: 282 FRIEK--KGVRYLMGGRTFECLDAVINRY 308
++I K G Y+ FE L ++ Y
Sbjct: 203 YKIRKLDNGGYYITTRAQFETLQQLVQHY 231
>BC032413-1|AAH32413.1| 505|Homo sapiens B lymphoid tyrosine kinase
protein.
Length = 505
Score = 49.6 bits (113), Expect = 5e-05
Identities = 48/156 (30%), Positives = 73/156 (46%), Gaps = 14/156 (8%)
Query: 164 DKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDL 223
DK VVA+ YT M D D L KG+ V GD WL + TG +G + V +
Sbjct: 59 DKHFVVALYDYTAMNDRD-LQMLKGEKLQVLKGTGDWWL-ARSLVTGREGYVPSNFVARV 116
Query: 224 DPSIDPNTVFSWFHPNCTKSEAVDMLVKA--GPGSFLVRPSDNSPGDYSLFF-HINNQ-- 278
+ S++ WF + + EA L+ GSFL+R S+ + G +SL + Q
Sbjct: 117 E-SLEMER---WFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTTQGE 172
Query: 279 -IQRFRIE--KKGVRYLMGGRTFECLDAVINRYRKE 311
I+ ++I +G Y+ TF L A++ Y K+
Sbjct: 173 LIKHYKIRCLDEGGYYISPRITFPSLQALVQHYSKK 208
Score = 41.9 bits (94), Expect = 0.010
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 7/87 (8%)
Query: 66 WYHGRLDRYTSEERLWAA-SKQGSYLVRESDRKPGSYVLSYLGRTG----INHFRITAVC 120
W+ R +E +L A +K GS+L+RES+ G++ LS T I H++I +
Sbjct: 124 WFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTTQGELIKHYKIRCLD 183
Query: 121 -GDYYIGGR-QFDSLTELVGFYSHCSD 145
G YYI R F SL LV YS D
Sbjct: 184 EGGYYISPRITFPSLQALVQHYSKKGD 210
>BC018703-1|AAH18703.1| 599|Homo sapiens Unknown (protein for
IMAGE:4574968) protein.
Length = 599
Score = 49.6 bits (113), Expect = 5e-05
Identities = 48/156 (30%), Positives = 73/156 (46%), Gaps = 14/156 (8%)
Query: 164 DKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDL 223
DK VVA+ YT M D D L KG+ V GD WL + TG +G + V +
Sbjct: 59 DKHFVVALYDYTAMNDRD-LQMLKGEKLQVLKGTGDWWL-ARSLVTGREGYVPSNFVARV 116
Query: 224 DPSIDPNTVFSWFHPNCTKSEAVDMLVKA--GPGSFLVRPSDNSPGDYSLFF-HINNQ-- 278
+ S++ WF + + EA L+ GSFL+R S+ + G +SL + Q
Sbjct: 117 E-SLEMER---WFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTTQGE 172
Query: 279 -IQRFRIE--KKGVRYLMGGRTFECLDAVINRYRKE 311
I+ ++I +G Y+ TF L A++ Y K+
Sbjct: 173 LIKHYKIRCLDEGGYYISPRITFPSLQALVQHYSKK 208
Score = 41.9 bits (94), Expect = 0.010
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 7/87 (8%)
Query: 66 WYHGRLDRYTSEERLWAA-SKQGSYLVRESDRKPGSYVLSYLGRTG----INHFRITAVC 120
W+ R +E +L A +K GS+L+RES+ G++ LS T I H++I +
Sbjct: 124 WFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTTQGELIKHYKIRCLD 183
Query: 121 -GDYYIGGR-QFDSLTELVGFYSHCSD 145
G YYI R F SL LV YS D
Sbjct: 184 EGGYYISPRITFPSLQALVQHYSKKGD 210
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.136 0.422
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 143,152,472
Number of Sequences: 224733
Number of extensions: 6258574
Number of successful extensions: 13181
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 325
Number of HSP's successfully gapped in prelim test: 349
Number of HSP's that attempted gapping in prelim test: 11743
Number of HSP's gapped (non-prelim): 1315
length of query: 932
length of database: 73,234,838
effective HSP length: 97
effective length of query: 835
effective length of database: 51,435,737
effective search space: 42948840395
effective search space used: 42948840395
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 70 (32.3 bits)
- SilkBase 1999-2023 -