Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001557-TA|BGIBMGA001557-PA|IPR005821|Ion transport,
IPR010526|Sodium ion transport-associated, IPR001696|Na+ channel,
IPR002048|Calcium-binding EF-hand
(1969 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P35500-9 Cluster: Isoform exond of P35500 ; n=24; Arthr... 2762 0.0
UniRef50_P35500 Cluster: Sodium channel protein para; n=55; Arth... 1758 0.0
UniRef50_Q67FT1 Cluster: Voltage-gated sodium channel protein; n... 1314 0.0
UniRef50_Q86D77 Cluster: Sodium channel protein; n=3; Eukaryota|... 1069 0.0
UniRef50_Q14524 Cluster: Sodium channel protein type 5 subunit a... 979 0.0
UniRef50_Q25377 Cluster: Sodium channel; n=1; Loligo opalescens|... 914 0.0
UniRef50_P90670 Cluster: Sodium channel alpha-subunit SCAP1; n=1... 873 0.0
UniRef50_P35499 Cluster: Sodium channel protein type 4 subunit a... 842 0.0
UniRef50_UPI0000ECCB92 Cluster: Voltage-gated sodium channel H; ... 842 0.0
UniRef50_P08104 Cluster: Sodium channel protein type 3 subunit a... 837 0.0
UniRef50_Q4S316 Cluster: Chromosome 3 SCAF14756, whole genome sh... 832 0.0
UniRef50_Q4SNV9 Cluster: Chromosome 15 SCAF14542, whole genome s... 822 0.0
UniRef50_UPI00015A61DE Cluster: sodium channel, voltage-gated, t... 820 0.0
UniRef50_P35498 Cluster: Sodium channel protein type 1 subunit a... 819 0.0
UniRef50_UPI0000ECCD59 Cluster: Voltage-gated sodium channel SNS... 808 0.0
UniRef50_Q9Y5Y9 Cluster: Sodium channel protein type 10 subunit ... 802 0.0
UniRef50_Q2XVR7 Cluster: Voltage-gated sodium channel Nav1.4a; n... 791 0.0
UniRef50_Q25150 Cluster: Voltage-gated sodium channel; n=1; Halo... 767 0.0
UniRef50_Q4RYI3 Cluster: Chromosome 2 SCAF14976, whole genome sh... 767 0.0
UniRef50_P02719 Cluster: Sodium channel protein (Na(+) channel);... 765 0.0
UniRef50_Q4T100 Cluster: Chromosome undetermined SCAF10773, whol... 763 0.0
UniRef50_Q9UI33 Cluster: Sodium channel protein type 11 subunit ... 756 0.0
UniRef50_Q16JN2 Cluster: Voltage-gated sodium channel; n=3; Endo... 735 0.0
UniRef50_Q7QIV0 Cluster: ENSANGP00000011132; n=1; Anopheles gamb... 726 0.0
UniRef50_Q5D735 Cluster: Voltage-dependent sodium channel; n=1; ... 722 0.0
UniRef50_Q9W0Y8 Cluster: Sodium channel protein 60E; n=3; Drosop... 720 0.0
UniRef50_O02037 Cluster: Voltage-gated sodium channel homolog Bd... 720 0.0
UniRef50_UPI0000E48802 Cluster: PREDICTED: similar to CG9071-PA;... 688 0.0
UniRef50_Q05973 Cluster: Sodium channel protein I, brain; n=1; L... 688 0.0
UniRef50_A7SKR1 Cluster: Predicted protein; n=3; Nematostella ve... 676 0.0
UniRef50_O44930 Cluster: Putative voltage-gated sodium channel; ... 653 0.0
UniRef50_Q9NKV1 Cluster: Sodium channel; n=3; Chordata|Rep: Sodi... 634 e-180
UniRef50_UPI0000F2D000 Cluster: PREDICTED: similar to voltage-ga... 612 e-173
UniRef50_O62604 Cluster: Voltage-gated sodium channel alpha subu... 611 e-173
UniRef50_Q17314 Cluster: Sodium channel; n=1; Cyanea capillata|R... 598 e-169
UniRef50_Q01118 Cluster: Sodium channel protein type 7 subunit a... 596 e-168
UniRef50_A7RP56 Cluster: Predicted protein; n=1; Nematostella ve... 545 e-153
UniRef50_UPI000065F7BA Cluster: Homolog of Takifugu pardalis "Vo... 503 e-140
UniRef50_Q4RQI5 Cluster: Chromosome 2 SCAF15004, whole genome sh... 491 e-136
UniRef50_A6N7F3 Cluster: Sodium channel protein; n=5; Coelomata|... 478 e-133
UniRef50_Q4S161 Cluster: Chromosome 13 SCAF14769, whole genome s... 442 e-122
UniRef50_UPI000069E3BF Cluster: Sodium channel protein type 4 su... 411 e-113
UniRef50_Q4S1P9 Cluster: Chromosome 11 SCAF14767, whole genome s... 344 1e-92
UniRef50_A5YW88 Cluster: Voltage-gated calcium channel alpha 1 s... 331 1e-88
UniRef50_Q15878 Cluster: Voltage-dependent R-type calcium channe... 329 5e-88
UniRef50_UPI000069E8BB Cluster: Voltage-dependent T-type calcium... 328 7e-88
UniRef50_A0D627 Cluster: Chromosome undetermined scaffold_39, wh... 328 9e-88
UniRef50_Q5PTC3 Cluster: Voltage gated sodium channel; n=142; Pa... 323 3e-86
UniRef50_Q869H0 Cluster: Voltage-dependent T-type calcium channe... 321 1e-85
UniRef50_Q00975 Cluster: Voltage-dependent N-type calcium channe... 320 2e-85
UniRef50_O54898 Cluster: Voltage-dependent T-type calcium channe... 320 2e-85
UniRef50_O02038 Cluster: Voltage-gated calcium channel alpha-1 s... 319 6e-85
UniRef50_Q869H4 Cluster: Voltage-dependent L-type calcium channe... 318 1e-84
UniRef50_A0BV23 Cluster: Chromosome undetermined scaffold_13, wh... 317 2e-84
UniRef50_O00555 Cluster: Voltage-dependent P/Q-type calcium chan... 315 7e-84
UniRef50_A4RYT5 Cluster: VIC family transporter: calcium ion cha... 315 9e-84
UniRef50_P91744 Cluster: Voltage-dependent calcium channel; n=1;... 315 9e-84
UniRef50_O95180 Cluster: Voltage-dependent T-type calcium channe... 315 9e-84
UniRef50_Q8MQA1 Cluster: Egg laying defective protein 19, isofor... 314 2e-83
UniRef50_O43497 Cluster: Voltage-dependent T-type calcium channe... 314 2e-83
UniRef50_Q99246 Cluster: Voltage-dependent L-type calcium channe... 314 2e-83
UniRef50_A7SHI0 Cluster: Predicted protein; n=2; Nematostella ve... 314 2e-83
UniRef50_Q9P0X4 Cluster: Voltage-dependent T-type calcium channe... 314 2e-83
UniRef50_Q01668 Cluster: Voltage-dependent L-type calcium channe... 314 2e-83
UniRef50_O60840 Cluster: Voltage-dependent L-type calcium channe... 313 3e-83
UniRef50_Q869H2 Cluster: Voltage-dependent non-L-type calcium ch... 310 3e-82
UniRef50_O57483 Cluster: Voltage-dependent L-type calcium channe... 310 3e-82
UniRef50_P56699 Cluster: Probable voltage-dependent R-type calci... 309 5e-82
UniRef50_Q13698 Cluster: Voltage-dependent L-type calcium channe... 308 8e-82
UniRef50_Q7Z003 Cluster: T-type calcium channel alpha1 subunit i... 308 1e-81
UniRef50_Q4S5H0 Cluster: Chromosome 3 SCAF14730, whole genome sh... 306 3e-81
UniRef50_Q8JFR0 Cluster: Voltage-gated calcium channel subunit C... 306 4e-81
UniRef50_Q24270 Cluster: Voltage-dependent calcium channel type ... 304 1e-80
UniRef50_P91645 Cluster: Voltage-dependent calcium channel type ... 303 3e-80
UniRef50_Q7PQV4 Cluster: ENSANGP00000003024; n=1; Anopheles gamb... 303 4e-80
UniRef50_UPI00015B53F6 Cluster: PREDICTED: similar to voltage- g... 300 3e-79
UniRef50_UPI000065EC32 Cluster: Voltage-dependent R-type calcium... 297 3e-78
UniRef50_Q86G45 Cluster: High voltage activated calcium channel ... 296 5e-78
UniRef50_Q9W433 Cluster: CG15899-PB; n=16; Eumetazoa|Rep: CG1589... 295 1e-77
UniRef50_Q4RGG8 Cluster: Chromosome 18 SCAF15100, whole genome s... 289 7e-76
UniRef50_Q963L8 Cluster: High voltage-activated calcium channel ... 289 7e-76
UniRef50_Q963L7 Cluster: High voltage-activated calcium channel ... 289 7e-76
UniRef50_Q4S9J4 Cluster: Chromosome undetermined SCAF14696, whol... 286 4e-75
UniRef50_A0C2L5 Cluster: Chromosome undetermined scaffold_145, w... 284 1e-74
UniRef50_Q4RUD9 Cluster: Chromosome 1 SCAF14995, whole genome sh... 284 2e-74
UniRef50_Q611Z7 Cluster: Putative uncharacterized protein CBG168... 281 2e-73
UniRef50_A0CTH2 Cluster: Chromosome undetermined scaffold_27, wh... 279 6e-73
UniRef50_A0CTU2 Cluster: Chromosome undetermined scaffold_27, wh... 277 3e-72
UniRef50_Q23FG9 Cluster: Cation channel family protein; n=1; Tet... 264 1e-68
UniRef50_UPI0000F2E940 Cluster: PREDICTED: similar to voltage-ga... 262 9e-68
UniRef50_UPI000051A6E6 Cluster: PREDICTED: similar to Ca-1T CG15... 258 1e-66
UniRef50_UPI000065DC23 Cluster: Voltage-dependent T-type calcium... 257 3e-66
UniRef50_A0DRJ4 Cluster: Chromosome undetermined scaffold_60, wh... 256 4e-66
UniRef50_A4RW52 Cluster: VIC family transporter: calcium ion cha... 255 8e-66
UniRef50_Q4S7Y3 Cluster: Chromosome 9 SCAF14710, whole genome sh... 244 1e-62
UniRef50_Q4Q3G0 Cluster: Calcium channel protein, putative; n=3;... 239 7e-61
UniRef50_A0DR68 Cluster: Chromosome undetermined scaffold_60, wh... 238 1e-60
UniRef50_A4S9Q8 Cluster: VIC family transporter: calcium ion cha... 237 2e-60
UniRef50_Q01FC6 Cluster: CAC1H_MOUSE Voltage-dependent T-type ca... 235 7e-60
UniRef50_Q4RB88 Cluster: Chromosome undetermined SCAF21986, whol... 234 2e-59
UniRef50_Q4SLL1 Cluster: Chromosome 15 SCAF14556, whole genome s... 234 2e-59
UniRef50_Q23ZH3 Cluster: Cation channel family protein; n=2; Tet... 233 3e-59
UniRef50_A2BHF3 Cluster: Novel protein similar to vertebrate cal... 233 5e-59
UniRef50_Q01AV1 Cluster: Calcium channel, voltage-dependent, T t... 228 1e-57
UniRef50_A0BZH2 Cluster: Chromosome undetermined scaffold_139, w... 228 1e-57
UniRef50_A0DXP6 Cluster: Chromosome undetermined scaffold_69, wh... 223 4e-56
UniRef50_Q23ZH4 Cluster: Cation channel family protein; n=1; Tet... 221 2e-55
UniRef50_Q4S5I1 Cluster: Chromosome 3 SCAF14730, whole genome sh... 217 3e-54
UniRef50_Q4RZH4 Cluster: Chromosome undetermined SCAF14924, whol... 213 5e-53
UniRef50_Q13936 Cluster: Voltage-dependent L-type calcium channe... 210 2e-52
UniRef50_Q4STU7 Cluster: Chromosome undetermined SCAF14113, whol... 210 3e-52
UniRef50_Q4DZ99 Cluster: Calcium channel protein, putative; n=2;... 206 4e-51
UniRef50_O42421 Cluster: Voltage-gated sodium channel SNS; n=2; ... 206 6e-51
UniRef50_UPI00015A3E26 Cluster: UPI00015A3E26 related cluster; n... 202 6e-50
UniRef50_A4RQQ5 Cluster: VIC family transporter: calcium ion cha... 200 2e-49
UniRef50_Q4RXK3 Cluster: Chromosome 11 SCAF14979, whole genome s... 197 3e-48
UniRef50_A0DXC4 Cluster: Chromosome undetermined scaffold_68, wh... 194 2e-47
UniRef50_Q6C5T4 Cluster: Similar to sp|P50077 Saccharomyces cere... 193 5e-47
UniRef50_A0D436 Cluster: Chromosome undetermined scaffold_37, wh... 189 6e-46
UniRef50_A0BKL8 Cluster: Chromosome undetermined scaffold_112, w... 188 1e-45
UniRef50_Q4SSZ6 Cluster: Chromosome undetermined SCAF14338, whol... 187 3e-45
UniRef50_Q00ST7 Cluster: Voltage-gated Ca2+ channels, alpha1 sub... 182 9e-44
UniRef50_Q22XZ8 Cluster: Cation channel family protein; n=1; Tet... 181 2e-43
UniRef50_A0BF12 Cluster: Chromosome undetermined scaffold_103, w... 175 8e-42
UniRef50_A0CBV7 Cluster: Chromosome undetermined scaffold_165, w... 175 1e-41
UniRef50_O14234 Cluster: VIC sodium channel; n=1; Schizosaccharo... 172 7e-41
UniRef50_A0DI39 Cluster: Chromosome undetermined scaffold_51, wh... 169 5e-40
UniRef50_A1CQ08 Cluster: Calcium channel subunit Cch1; n=9; Pezi... 169 7e-40
UniRef50_A0D5W4 Cluster: Chromosome undetermined scaffold_39, wh... 167 4e-39
UniRef50_A0DXQ5 Cluster: Chromosome undetermined scaffold_69, wh... 165 8e-39
UniRef50_Q8IZF0 Cluster: Voltage gated channel-like protein 1; n... 165 1e-38
UniRef50_A7RTZ7 Cluster: Predicted protein; n=2; Nematostella ve... 164 2e-38
UniRef50_A0D437 Cluster: Chromosome undetermined scaffold_37, wh... 164 2e-38
UniRef50_Q4P355 Cluster: Putative uncharacterized protein; n=1; ... 164 3e-38
UniRef50_Q9VY40 Cluster: CG1517-PB, isoform B; n=12; Coelomata|R... 163 6e-38
UniRef50_A0DX61 Cluster: Chromosome undetermined scaffold_68, wh... 163 6e-38
UniRef50_A0BDT8 Cluster: Chromosome undetermined scaffold_101, w... 162 1e-37
UniRef50_P50077 Cluster: Calcium-channel protein CCH1; n=4; cell... 155 2e-35
UniRef50_Q7SCM1 Cluster: Putative uncharacterized protein NCU027... 153 5e-35
UniRef50_Q22YT0 Cluster: Cation channel family protein; n=1; Tet... 152 1e-34
UniRef50_Q1HHN2 Cluster: High-affinity cell membrane calcium cha... 149 6e-34
UniRef50_Q4SZH3 Cluster: Chromosome 18 SCAF11624, whole genome s... 148 1e-33
UniRef50_A0DI68 Cluster: Chromosome undetermined scaffold_51, wh... 148 1e-33
UniRef50_Q06AY4 Cluster: Four domain-type voltage-gated ion chan... 147 3e-33
UniRef50_Q6CN16 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 147 3e-33
UniRef50_O42398 Cluster: Voltage-dependent L-type calcium channe... 145 1e-32
UniRef50_Q8T769 Cluster: Putative uncharacterized protein; n=1; ... 144 2e-32
UniRef50_A7TEU5 Cluster: Putative uncharacterized protein; n=1; ... 143 5e-32
UniRef50_Q6Q762 Cluster: Four domain-type voltage-gated ion chan... 140 5e-31
UniRef50_Q4SMF4 Cluster: Chromosome undetermined SCAF14551, whol... 139 8e-31
UniRef50_UPI0000F1D26B Cluster: PREDICTED: similar to calcium ch... 138 1e-30
UniRef50_A0BDK4 Cluster: Chromosome undetermined scaffold_100, w... 137 2e-30
UniRef50_A0BZH6 Cluster: Chromosome undetermined scaffold_139, w... 136 6e-30
UniRef50_Q23DY9 Cluster: Cation channel family protein; n=2; Alv... 135 1e-29
UniRef50_A0BKE9 Cluster: Chromosome undetermined scaffold_112, w... 134 2e-29
UniRef50_A0DB70 Cluster: Chromosome undetermined scaffold_44, wh... 131 2e-28
UniRef50_A5DB80 Cluster: Putative uncharacterized protein; n=1; ... 129 9e-28
UniRef50_UPI000065FCC5 Cluster: Voltage-dependent T-type calcium... 124 3e-26
UniRef50_A7SZ40 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 124 3e-26
UniRef50_A2AFU9 Cluster: Calcium channel voltage-dependent alpha... 116 7e-24
UniRef50_A7TIK0 Cluster: Putative uncharacterized protein; n=1; ... 115 1e-23
UniRef50_UPI00015A4429 Cluster: UPI00015A4429 related cluster; n... 109 1e-21
UniRef50_A7E792 Cluster: Putative uncharacterized protein; n=2; ... 104 2e-20
UniRef50_A6QWN8 Cluster: Putative uncharacterized protein; n=1; ... 102 9e-20
UniRef50_Q2HAK7 Cluster: Putative uncharacterized protein; n=1; ... 101 3e-19
UniRef50_Q9UDC3 Cluster: Neuronal-type voltage-gated CA2+ channe... 100 3e-19
UniRef50_UPI00006CBCBD Cluster: cation channel family protein; n... 100 8e-19
UniRef50_Q22N11 Cluster: Cation channel family protein; n=1; Tet... 97 6e-18
UniRef50_Q65MK7 Cluster: Putative uncharacterized protein; n=1; ... 96 8e-18
UniRef50_A3EY19 Cluster: Cardiac sodium channel alpha subunit va... 93 5e-17
UniRef50_UPI0000ECA7B2 Cluster: Voltage-dependent N-type calcium... 93 7e-17
UniRef50_O73707 Cluster: Voltage-dependent L-type calcium channe... 93 9e-17
UniRef50_Q22N13 Cluster: Cation channel family protein; n=1; Tet... 91 3e-16
UniRef50_A5DVK1 Cluster: Putative uncharacterized protein; n=1; ... 90 5e-16
UniRef50_A6GA84 Cluster: K+ transporter, Kef-type; n=1; Plesiocy... 90 7e-16
UniRef50_Q9U6N6 Cluster: Calcium channel alpha-1 subunit; n=2; B... 89 9e-16
UniRef50_Q16MR6 Cluster: Putative uncharacterized protein; n=1; ... 89 9e-16
UniRef50_Q86XQ3 Cluster: Cation channel sperm-associated protein... 86 1e-14
UniRef50_Q9KCR8 Cluster: BH1501 protein; n=4; Bacillaceae|Rep: B... 85 1e-14
UniRef50_O73706 Cluster: Voltage-dependent N-type calcium channe... 85 2e-14
UniRef50_Q4RWE1 Cluster: Chromosome 2 SCAF14990, whole genome sh... 84 3e-14
UniRef50_UPI0000E23FE5 Cluster: PREDICTED: similar to calcium ch... 83 6e-14
UniRef50_Q96P56-3 Cluster: Isoform 3 of Q96P56 ; n=4; Mammalia|R... 83 7e-14
UniRef50_Q96P56 Cluster: Cation channel sperm-associated protein... 83 7e-14
UniRef50_Q91ZR5 Cluster: Cation channel sperm-associated protein... 83 7e-14
UniRef50_A7SLD2 Cluster: Predicted protein; n=1; Nematostella ve... 83 1e-13
UniRef50_A3UK17 Cluster: Cation channel family protein; n=2; Hyp... 82 1e-13
UniRef50_A3W0R4 Cluster: Voltage-gated sodium channel; n=8; Alph... 81 3e-13
UniRef50_A7STF7 Cluster: Predicted protein; n=1; Nematostella ve... 80 5e-13
UniRef50_A7RF81 Cluster: Predicted protein; n=1; Nematostella ve... 79 2e-12
UniRef50_Q4STU8 Cluster: Chromosome undetermined SCAF14113, whol... 77 4e-12
UniRef50_Q4QE45 Cluster: Putative uncharacterized protein; n=3; ... 77 5e-12
UniRef50_A6W2Y2 Cluster: Ion transport protein; n=12; Gammaprote... 76 1e-11
UniRef50_UPI0000EBD484 Cluster: PREDICTED: similar to N-type cal... 75 2e-11
UniRef50_Q5QZT4 Cluster: Kef-type K+ transport system, NAD-bindi... 75 2e-11
UniRef50_A1RP00 Cluster: Ion transport protein; n=12; Proteobact... 75 3e-11
UniRef50_Q9GZR0 Cluster: Voltage-gated sodium channel; n=18; Tet... 75 3e-11
UniRef50_Q47SZ6 Cluster: Putative uncharacterized protein; n=1; ... 74 3e-11
UniRef50_A0NR80 Cluster: Ion transport protein; n=11; Bacteria|R... 74 5e-11
UniRef50_Q22YT3 Cluster: Cation channel family protein; n=1; Tet... 74 5e-11
UniRef50_A7S9M8 Cluster: Predicted protein; n=1; Nematostella ve... 74 5e-11
UniRef50_Q22YS7 Cluster: Cation channel family protein; n=1; Tet... 73 6e-11
UniRef50_Q22YS9 Cluster: Cation channel family protein; n=1; Tet... 73 8e-11
UniRef50_Q0F227 Cluster: Ion transport protein; n=1; Mariprofund... 73 1e-10
UniRef50_Q47UV3 Cluster: Cation channel family protein; n=2; Col... 72 1e-10
UniRef50_UPI0000F2E29A Cluster: PREDICTED: similar to sperm ion ... 72 2e-10
UniRef50_Q22BI8 Cluster: Cation channel family protein; n=1; Tet... 72 2e-10
UniRef50_A4GJA9 Cluster: Putative ion transport protein; n=1; un... 71 3e-10
UniRef50_Q0BXG6 Cluster: Cation channel family protein; n=2; Hyp... 70 6e-10
UniRef50_Q7RTX7 Cluster: Cation channel sperm-associated protein... 70 7e-10
UniRef50_UPI0001555295 Cluster: PREDICTED: similar to CatSper4, ... 69 1e-09
UniRef50_UPI0000F1F6F8 Cluster: PREDICTED: hypothetical protein;... 69 1e-09
UniRef50_A4TVG1 Cluster: Ion transport protein; n=1; Magnetospir... 69 2e-09
UniRef50_Q1GCI9 Cluster: Voltage-gated sodium channel; n=4; Rhod... 68 3e-09
UniRef50_A0L5S6 Cluster: Ion transport protein precursor; n=4; P... 68 3e-09
UniRef50_A4S304 Cluster: VIC family transporter: sodium/calcium ... 67 4e-09
UniRef50_A7RH57 Cluster: Predicted protein; n=2; Nematostella ve... 67 4e-09
UniRef50_Q9ULQ1 Cluster: Two pore calcium channel protein 1; n=2... 67 4e-09
UniRef50_A1WZ39 Cluster: Ion transport protein; n=5; Proteobacte... 66 7e-09
UniRef50_A7SGC6 Cluster: Predicted protein; n=1; Nematostella ve... 66 7e-09
UniRef50_Q8NEC5 Cluster: Cation channel sperm-associated protein... 66 7e-09
UniRef50_UPI0000F1EB94 Cluster: PREDICTED: hypothetical protein;... 66 9e-09
UniRef50_UPI0000E47103 Cluster: PREDICTED: similar to sperm-asso... 66 1e-08
UniRef50_A5DVK2 Cluster: Putative uncharacterized protein; n=1; ... 66 1e-08
UniRef50_UPI000155F67E Cluster: PREDICTED: hypothetical protein;... 65 2e-08
UniRef50_A7RM05 Cluster: Predicted protein; n=1; Nematostella ve... 65 2e-08
UniRef50_Q1RKX8 Cluster: IP14892p; n=1; Drosophila melanogaster|... 64 4e-08
UniRef50_A0EAP2 Cluster: Chromosome undetermined scaffold_86, wh... 64 5e-08
UniRef50_UPI0000D565C8 Cluster: PREDICTED: similar to two pore c... 63 6e-08
UniRef50_Q4RST2 Cluster: Chromosome 12 SCAF14999, whole genome s... 63 6e-08
UniRef50_Q3HWU6 Cluster: Non L-type Cav channel; n=4; Strongyloc... 63 6e-08
UniRef50_UPI00015B4201 Cluster: PREDICTED: similar to two pore c... 62 2e-07
UniRef50_A4FDR4 Cluster: Voltage-gated sodium channel; n=1; Sacc... 61 3e-07
UniRef50_A1ZWP3 Cluster: Transporter, cation channel family; n=1... 60 6e-07
UniRef50_A7TIJ9 Cluster: Putative uncharacterized protein; n=1; ... 60 6e-07
UniRef50_Q22SA3 Cluster: Cation channel family protein; n=1; Tet... 60 8e-07
UniRef50_Q22N12 Cluster: Putative uncharacterized protein; n=1; ... 58 2e-06
UniRef50_UPI0000E45EB7 Cluster: PREDICTED: similar to calcium ch... 58 2e-06
UniRef50_Q4G0N8-2 Cluster: Isoform 2 of Q4G0N8 ; n=4; Catarrhini... 58 2e-06
UniRef50_Q4G0N8 Cluster: Sodium/hydrogen exchanger 10 (Na(+)/H(+... 58 2e-06
UniRef50_A3RL54 Cluster: Sperm-specific sodium proton exchanger;... 57 4e-06
UniRef50_UPI0000E4A226 Cluster: PREDICTED: similar to four domai... 56 7e-06
UniRef50_UPI0000E4670D Cluster: PREDICTED: similar to voltage-de... 56 1e-05
UniRef50_Q6TMY6 Cluster: Putative voltage-gated cation channel s... 54 5e-05
UniRef50_Q14721 Cluster: Potassium voltage-gated channel subfami... 54 5e-05
UniRef50_UPI0000ECC6B0 Cluster: UPI0000ECC6B0 related cluster; n... 52 2e-04
UniRef50_UPI0000E46611 Cluster: PREDICTED: similar to putative f... 51 3e-04
UniRef50_Q23RF4 Cluster: Cation channel family protein; n=1; Tet... 51 3e-04
UniRef50_Q12VA9 Cluster: Ion transport protein; n=2; cellular or... 51 3e-04
UniRef50_Q5QM84 Cluster: Two pore calcium channel protein 1; n=1... 51 3e-04
UniRef50_Q92953 Cluster: Potassium voltage-gated channel subfami... 51 3e-04
UniRef50_Q54HZ8 Cluster: Putative Ca2+ channel; n=1; Dictyosteli... 50 5e-04
UniRef50_A0BF28 Cluster: Chromosome undetermined scaffold_103, w... 50 6e-04
UniRef50_A0B9H8 Cluster: Ion transport 2 domain protein; n=1; Me... 50 6e-04
UniRef50_UPI00015557BE Cluster: PREDICTED: similar to potassium ... 50 9e-04
UniRef50_Q4T7V1 Cluster: Chromosome undetermined SCAF7977, whole... 50 9e-04
UniRef50_A5L2U9 Cluster: Putative uncharacterized protein; n=1; ... 50 9e-04
UniRef50_A7RQS2 Cluster: Predicted protein; n=1; Nematostella ve... 49 0.001
UniRef50_Q4T8N0 Cluster: Chromosome undetermined SCAF7762, whole... 49 0.001
UniRef50_Q23RI8 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 49 0.001
UniRef50_O97045 Cluster: Kv2 channel alpha-subunit; n=1; Halocyn... 49 0.001
UniRef50_A7SIU6 Cluster: Predicted protein; n=1; Nematostella ve... 49 0.001
UniRef50_Q8NHX9 Cluster: Two pore calcium channel protein 2; n=3... 48 0.002
UniRef50_UPI0000DA1AE7 Cluster: PREDICTED: similar to two pore s... 48 0.003
UniRef50_Q46XI1 Cluster: Ion transport protein; n=5; Proteobacte... 48 0.003
UniRef50_Q75VR0 Cluster: Two-pore calcium channel; n=3; Embryoph... 47 0.005
UniRef50_A7SWG0 Cluster: Predicted protein; n=1; Nematostella ve... 47 0.005
UniRef50_A7S8W8 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 47 0.005
UniRef50_Q3B1E8 Cluster: Potassium channel protein; n=8; Bacteri... 46 0.008
UniRef50_UPI0000E493F8 Cluster: PREDICTED: similar to Two pore s... 46 0.011
UniRef50_A7ULH7 Cluster: Voltage-gated proton channel; n=1; Stro... 46 0.014
UniRef50_UPI0001509C5D Cluster: cation channel family protein; n... 45 0.018
UniRef50_UPI0000E4A2AB Cluster: PREDICTED: similar to calcium ch... 45 0.018
UniRef50_Q5MZA2 Cluster: Potassium channel protein; n=2; Synecho... 45 0.018
UniRef50_A0Z1R1 Cluster: Putative uncharacterized protein; n=2; ... 45 0.018
UniRef50_A7RIZ7 Cluster: Predicted protein; n=1; Nematostella ve... 45 0.024
UniRef50_Q9H3M0 Cluster: Potassium voltage-gated channel subfami... 45 0.024
UniRef50_Q9UK17 Cluster: Potassium voltage-gated channel subfami... 45 0.024
UniRef50_UPI000155BA1B Cluster: PREDICTED: similar to two pore s... 44 0.032
UniRef50_A7SI06 Cluster: Predicted protein; n=1; Nematostella ve... 44 0.032
UniRef50_Q03721 Cluster: Potassium voltage-gated channel subfami... 44 0.056
UniRef50_Q9PDF3 Cluster: Ion transporter; n=14; Proteobacteria|R... 43 0.098
UniRef50_Q2JXB5 Cluster: Cation transporter, voltage-gated ion c... 43 0.098
UniRef50_A4BZF6 Cluster: Cation channel family protein; n=3; Fla... 43 0.098
UniRef50_Q26344 Cluster: Action potential broadening potassium c... 43 0.098
UniRef50_A0CJN3 Cluster: Chromosome undetermined scaffold_2, who... 43 0.098
UniRef50_P17970 Cluster: Potassium voltage-gated channel protein... 42 0.13
UniRef50_UPI00015562C5 Cluster: PREDICTED: hypothetical protein,... 42 0.17
UniRef50_Q23AZ3 Cluster: 3'5'-cyclic nucleotide phosphodiesteras... 42 0.17
UniRef50_Q96D96 Cluster: Hydrogen voltage-gated channel 1; n=29;... 42 0.17
UniRef50_Q8TDN2 Cluster: Potassium voltage-gated channel subfami... 42 0.17
UniRef50_UPI00015B4D72 Cluster: PREDICTED: similar to CG1066-PA;... 42 0.23
UniRef50_UPI0000E4A0D9 Cluster: PREDICTED: similar to low voltag... 42 0.23
UniRef50_A7SWZ3 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.23
UniRef50_A7SF11 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.23
UniRef50_A0IJG8 Cluster: Ion transport protein; n=1; Serratia pr... 41 0.30
UniRef50_O18476 Cluster: Kv2 voltage-gated potassium channel; n=... 41 0.30
UniRef50_Q5TAH2 Cluster: Sodium/hydrogen exchanger 11 (Na(+)/H(+... 41 0.30
UniRef50_Q21313 Cluster: Laminin-like protein epi-1 precursor; n... 41 0.30
UniRef50_UPI00006CA856 Cluster: cation channel family protein; n... 41 0.40
UniRef50_Q5M7E9 Cluster: LOC496219 protein; n=2; Xenopus|Rep: LO... 41 0.40
UniRef50_Q1QZN8 Cluster: Ion transport protein; n=1; Chromohalob... 41 0.40
UniRef50_A3ICA0 Cluster: Polysaccharide biosynthesis protein; n=... 41 0.40
UniRef50_UPI00006601FC Cluster: potassium voltage-gated channel,... 40 0.52
UniRef50_A0EFJ5 Cluster: Chromosome undetermined scaffold_93, wh... 40 0.52
UniRef50_Q2FTU0 Cluster: Ion transport protein; n=1; Methanospir... 40 0.52
UniRef50_P22001 Cluster: Potassium voltage-gated channel subfami... 40 0.52
UniRef50_UPI0000D62D9D Cluster: similar to sperm-specific sodium... 40 0.69
UniRef50_Q6DHQ1 Cluster: Zgc:92181; n=2; Danio rerio|Rep: Zgc:92... 40 0.69
UniRef50_Q9VK95 Cluster: CG6504-PA; n=3; Drosophila melanogaster... 40 0.69
UniRef50_Q00XF6 Cluster: Kv3.1 potassium channel; n=2; Ostreococ... 40 0.91
UniRef50_Q0ZNY3 Cluster: Transverse tubule dihydropyridine recep... 40 0.91
UniRef50_Q6R4N6 Cluster: Potassium channel Kv4; n=1; Ciona intes... 40 0.91
UniRef50_Q26094 Cluster: Potassium channel homolog; n=2; Hydrozo... 40 0.91
UniRef50_A2R1Y4 Cluster: Contig An13c0080, complete genome; n=10... 40 0.91
UniRef50_Q4SBP7 Cluster: Chromosome 18 SCAF14665, whole genome s... 39 1.2
UniRef50_Q982C7 Cluster: Dipeptide transport system permease pro... 39 1.2
UniRef50_Q9U1S7 Cluster: Putative uncharacterized protein pkd-2;... 39 1.2
UniRef50_Q16976 Cluster: Noninactivating potassium channel; n=1;... 39 1.2
UniRef50_A4IJ73 Cluster: IP18036p; n=9; Coelomata|Rep: IP18036p ... 39 1.2
UniRef50_A5WE73 Cluster: Ion transport protein; n=21; Proteobact... 39 1.6
UniRef50_Q6BFH0 Cluster: K+ channel, putative; n=4; Paramecium t... 39 1.6
UniRef50_A7RLC8 Cluster: Predicted protein; n=1; Nematostella ve... 39 1.6
UniRef50_A7RL21 Cluster: Predicted protein; n=1; Nematostella ve... 39 1.6
UniRef50_A7RJZ6 Cluster: Predicted protein; n=1; Nematostella ve... 39 1.6
UniRef50_Q14003 Cluster: Potassium voltage-gated channel subfami... 39 1.6
UniRef50_UPI0001555B10 Cluster: PREDICTED: similar to coiled-coi... 38 2.1
UniRef50_O77361 Cluster: Putative uncharacterized protein MAL3P4... 38 2.1
UniRef50_A7I7M5 Cluster: Mg2+ transporter protein, CorA family p... 38 2.1
UniRef50_Q4RCC1 Cluster: Chromosome undetermined SCAF19287, whol... 38 2.8
UniRef50_Q7JPF0 Cluster: K (Potassium) voltage-gated sensory cha... 38 2.8
UniRef50_Q5CVY9 Cluster: Uncharacterized coiled coil protein; n=... 38 2.8
UniRef50_Q9UHJ4 Cluster: Neuronal potassium channel alpha subuni... 38 2.8
UniRef50_Q8AYN5 Cluster: Calcium transporter 2; n=3; Euteleostom... 38 3.7
UniRef50_Q8C0Z9 Cluster: 0 day neonate head cDNA, RIKEN full-len... 38 3.7
UniRef50_A4WB86 Cluster: Ion transport protein; n=7; Enterobacte... 38 3.7
UniRef50_Q26095 Cluster: Potassium channel homolog; n=2; Cnidari... 38 3.7
UniRef50_Q25199 Cluster: Tyrosine kinase receptor; n=7; Hydra|Re... 38 3.7
UniRef50_Q0ICW9 Cluster: Cation transporter, voltage-gated ion c... 37 4.9
UniRef50_A0KXX9 Cluster: Ion transport protein; n=43; Bacteria|R... 37 4.9
UniRef50_Q4P678 Cluster: Putative uncharacterized protein; n=1; ... 37 4.9
UniRef50_Q9BQ31 Cluster: Potassium voltage-gated channel subfami... 37 4.9
UniRef50_UPI0001509D29 Cluster: hypothetical protein TTHERM_0061... 37 6.4
UniRef50_Q4C4Z2 Cluster: Ion transport protein:Ion transport pro... 37 6.4
UniRef50_A7HKY4 Cluster: ABC-2 type transporter; n=1; Fervidobac... 37 6.4
UniRef50_A6TQ73 Cluster: Ion transport protein; n=1; Alkaliphilu... 37 6.4
UniRef50_A0YJW4 Cluster: Ion transport protein; n=1; Lyngbya sp.... 37 6.4
UniRef50_Q7RH73 Cluster: Hepatocellular carcinoma-associated ant... 37 6.4
UniRef50_Q4W8A1 Cluster: Voltage-sensor containing phosphatase; ... 37 6.4
UniRef50_A7RH64 Cluster: Predicted protein; n=1; Nematostella ve... 37 6.4
UniRef50_Q9NTG1 Cluster: Polycystic kidney disease and receptor ... 37 6.4
UniRef50_UPI0001554632 Cluster: PREDICTED: similar to polycystin... 36 8.5
UniRef50_UPI0000F2BC84 Cluster: PREDICTED: similar to AKAP121; n... 36 8.5
UniRef50_Q7MUC4 Cluster: Ion transporter; n=2; Bacteroidetes|Rep... 36 8.5
UniRef50_Q5X7V6 Cluster: Putative uncharacterized protein; n=4; ... 36 8.5
UniRef50_Q0EYV3 Cluster: Putative potassium channel protein; n=1... 36 8.5
UniRef50_A7SB30 Cluster: Predicted protein; n=2; Nematostella ve... 36 8.5
UniRef50_A0CZ03 Cluster: Chromosome undetermined scaffold_31, wh... 36 8.5
>UniRef50_P35500-9 Cluster: Isoform exond of P35500 ; n=24;
Arthropoda|Rep: Isoform exond of P35500 - Drosophila
melanogaster (Fruit fly)
Length = 2077
Score = 2762 bits (6853), Expect = 0.0
Identities = 1396/1977 (70%), Positives = 1525/1977 (77%), Gaps = 103/1977 (5%)
Query: 1 MSEDLDSISEEERSLFRPFTRESLXXXXXXXXXXXXKQKELEKKRAEGEV---------- 50
M+ED DSISEEERSLFRPFTRESL KQKELE+KRAEGEV
Sbjct: 1 MTEDSDSISEEERSLFRPFTRESLVQIEQRIAAEHEKQKELERKRAEGEVPQYGRKKKQK 60
Query: 51 --RYXXXXXXXGPQPDATLEQGLPLPVRMQGSFPLELASTPLEDIDPFYHNQTTFVVISK 108
RY GPQPD TLEQG+P+PVR+QGSFP ELASTPLEDIDP+Y N TFVV+SK
Sbjct: 61 EIRYDDEDEDEGPQPDPTLEQGVPIPVRLQGSFPPELASTPLEDIDPYYSNVLTFVVVSK 120
Query: 109 GKDIFRFSATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVES 168
GKDIFRFSA+ A+W+LDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVES
Sbjct: 121 GKDIFRFSASKAMWMLDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVES 180
Query: 169 TEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALR 228
TEVIFTGIYTFESAVKVMARGFIL PFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALR
Sbjct: 181 TEVIFTGIYTFESAVKVMARGFILCPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALR 240
Query: 229 TFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQK 288
TFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQK
Sbjct: 241 TFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQK 300
Query: 289 CVKVFPEDGSWGNLTDENWERFCQNETNWYGE--GGDYPLCGNSSGAGQCEPGYVCLQGF 346
C+K FP DGSWGNLTDENW+ +N +NWY E G +PLCGN SGAGQC+ YVCLQGF
Sbjct: 301 CIKKFPLDGSWGNLTDENWDYHNRNSSNWYSEDEGISFPLCGNISGAGQCDDDYVCLQGF 360
Query: 347 GPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQL-----------FFVVIIFLGSFYL 395
GPNPNYGYTSFD+FGWAFLSAFRLMTQD+WE+LYQL FF+VIIFLGSFYL
Sbjct: 361 GPNPNYGYTSFDSFGWAFLSAFRLMTQDFWEDLYQLVLRAAGPWHMLFFIVIIFLGSFYL 420
Query: 396 VNLILAIVAMSYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 455
VNLILAIVAMSY
Sbjct: 421 VNLILAIVAMSYDELQKKAEEEEAAEEEAIREAEEAAAAKAAKLEERANAQAQAAADAAA 480
Query: 456 XXXXXXX--XXKSPSDFSCQSYELFVNQERGNQDDNTRERMSLRSDPFQDSVSTQPAHKP 513
KSP+ +SC SYELFV E+GN DDN +E+MS+RS + + +P
Sbjct: 481 AEEAALHPEMAKSPT-YSCISYELFVGGEKGN-DDNNKEKMSIRSVEVESESVSVIQRQP 538
Query: 514 TATDTHDSARRPRKVSMASLSLPGSPFNLRRGSRGSHQMALXXXXXXXXXXXXXXXXLVL 573
T H A + RKVS SLSLPGSPFN+RRGSR SH+ + LVL
Sbjct: 539 APTTAHQ-ATKVRKVSTTSLSLPGSPFNIRRGSRSSHKYTIRNGRGRFGIPGSDRKPLVL 597
Query: 574 STYLDAQEHLPYADDSNAVTPMSEENGAIIIPVYYANLGSRHSSYTSHQSRLSYTSHGDL 633
STY DAQ+HLPYADDSNAVTPMSEENGAII+PVYY NLGSRHSSYTSHQSR+SYTSHGDL
Sbjct: 598 STYQDAQQHLPYADDSNAVTPMSEENGAIIVPVYYGNLGSRHSSYTSHQSRISYTSHGDL 657
Query: 634 LGGG-----KAQTKEARLRGRSASRNHSVTSQPHAYPLPRQDSSLASRPLREYEVSTTEC 688
LGG TKE++LR R+ +RN SV + + L R +YE+ EC
Sbjct: 658 LGGMAVMGVSTMTKESKLRNRN-TRNQSVGATNGGTTCLDTNHKLDHR---DYEIGL-EC 712
Query: 689 TDEAGKVLKPSSDNPFIESSQQPNVVDMRDVMVLNEIIEQA-GRQSRASELNVSVYYFPT 747
TDEAGK+ DNPFIE Q VVDM+DVMVLN+IIEQA GR SRAS+ VSVYYFPT
Sbjct: 713 TDEAGKI--KHHDNPFIEPVQTQTVVDMKDVMVLNDIIEQAAGRHSRASDRGVSVYYFPT 770
Query: 748 AEDDEDGPTFKEKLLDCLMKGIDFFCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVV 807
+DDEDGPTFK+K L+ ++KGID FCVWDCCW+WL+FQ++V+L+VFDPFVELFITLCIVV
Sbjct: 771 EDDDEDGPTFKDKALEVILKGIDVFCVWDCCWVWLKFQEWVSLIVFDPFVELFITLCIVV 830
Query: 808 NTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLC 867
NT+FMA+DHH+M+K+M++ LKSGNY A + +S F++
Sbjct: 831 NTMFMAMDHHDMNKEMERVLKSGNYFFTATFAIEATMKLMAMSPKYYFQEGWNIFDFIIV 890
Query: 868 II----IFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIES 923
+ + + V G+ + +D+ DRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIES
Sbjct: 891 ALSLLELGLEGVQGLSVLRSFRLDHKDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIES 950
Query: 924 MWDCMLVGDVSCIPFFLATVVIXXXXXXXXXXXXXXXXXXXXXXXTPTADQDTNKIAEAF 983
MWDCM VGDVSCIPFFLATVVI PTAD DTNKIAEAF
Sbjct: 951 MWDCMYVGDVSCIPFFLATVVIGNLVVLNLFLALLLSNFGSSSLSAPTADNDTNKIAEAF 1010
Query: 984 NRISRFIDWIKRNVADFLKLLKNKLTNQIAIH-----------------------APERV 1020
NRI RF W+KRN+AD KL++NKLTNQI+ + E
Sbjct: 1011 NRIGRFKSWVKRNIADCFKLIRNKLTNQISDQPSGERTNQISWIWSEGKGVCRCISAEHG 1070
Query: 1021 DNELELGTD--LDDAVLYKDKKLKDQVEVAIGDGMEFTIPGD---NKYKKGKILMNNINA 1075
DNELELG D L D ++ K K + Q+EVAIGDGMEFTI GD NK KK K L N
Sbjct: 1071 DNELELGHDEILADGLIKKGIKEQTQLEVAIGDGMEFTIHGDMKNNKPKKSKYLNN---- 1126
Query: 1076 ITDNHRDNRLDCELNHHGYPIQDDDTISQKSYGSHKIRSFKDESHKGSADTIDGEEKKDA 1135
DDDT S SYGSHK R FKDESHKGSA+T++GEEK+DA
Sbjct: 1127 --------------------ATDDDTASINSYGSHKNRPFKDESHKGSAETMEGEEKRDA 1166
Query: 1136 SXXXXXXXXXXXXXXXXXXXXGTLGKTDIKVGADEDVVDDTPADCCPEQCYQKFPFLAGD 1195
S G L I DED++D+ PADCCP+ Y+KFP LAGD
Sbjct: 1167 SKEDLGLDEELDEEGECEE--GPLDGDIIIHAHDEDILDEYPADCCPDSYYKKFPILAGD 1224
Query: 1196 DDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYM 1255
DDSPFWQGWG LRLKTF+LIEN YFETAVITMIL+SSLALALEDVHLP RPILQDILYYM
Sbjct: 1225 DDSPFWQGWGNLRLKTFQLIENKYFETAVITMILMSSLALALEDVHLPQRPILQDILYYM 1284
Query: 1256 DRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTM 1315
DRIFTVIFF+EMLIKWLALGF+ YFTNAWCWLDF+IVMVSLINFVA+L GAGGIQAFKTM
Sbjct: 1285 DRIFTVIFFLEMLIKWLALGFKVYFTNAWCWLDFVIVMVSLINFVASLVGAGGIQAFKTM 1344
Query: 1316 RTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK 1375
RTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK
Sbjct: 1345 RTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK 1404
Query: 1376 CVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDA 1435
C DMN T LSHEIIP++NAC ENYTW NS MNFDHVG AYLCLFQVATFKGWIQIMNDA
Sbjct: 1405 CEDMNGTKLSHEIIPNRNACESENYTWVNSAMNFDHVGNAYLCLFQVATFKGWIQIMNDA 1464
Query: 1436 IDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFM 1495
IDSREV +QPIRETNIYMYLY TLNLFIGVIIDNFNEQKKKAGGSLEMFM
Sbjct: 1465 IDSREVDKQPIRETNIYMYLYFVFFIIFGSFFTLNLFIGVIIDNFNEQKKKAGGSLEMFM 1524
Query: 1496 TEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTL 1555
TEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFD+IIMLFIGLNM TMTL
Sbjct: 1525 TEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDIIIMLFIGLNMFTMTL 1584
Query: 1556 DHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLV 1615
D Y S+T++AVLDYLN IF+VIFSSECLLKIFALRYHYF+EPWNLFD VVV+ SIL LV
Sbjct: 1585 DRYDASDTYNAVLDYLNAIFVVIFSSECLLKIFALRYHYFIEPWNLFDVVVVILSILGLV 1644
Query: 1616 LSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLV 1675
LSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLV
Sbjct: 1645 LSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLV 1704
Query: 1676 MFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECD 1735
MFIFAIFGMSFFMHVK+K G++DVYNFKTF QSMILLFQMSTSAGWDGVLD IINEE CD
Sbjct: 1705 MFIFAIFGMSFFMHVKEKSGINDVYNFKTFGQSMILLFQMSTSAGWDGVLDAIINEEACD 1764
Query: 1736 LPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDD 1795
PDN++G PGNCGSAT+GIT+LLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDD
Sbjct: 1765 PPDNDKGYPGNCGSATVGITFLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDD 1824
Query: 1796 YDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHKPNKYKIISMDIPICRGDMMFC 1855
YDMYYEIWQ+FDP+G+QYIRYDQLS+FLDVLEPPLQIHKPNKYKIISMDIPICRGD+M+C
Sbjct: 1825 YDMYYEIWQQFDPEGTQYIRYDQLSEFLDVLEPPLQIHKPNKYKIISMDIPICRGDLMYC 1884
Query: 1856 VDILDALTKDFFARKGNPIEETGDL-EV-GRPEEAGYEPVSSTLWRQREEYCARLIQ 1910
VDILDALTKDFFARKGNPIEETG++ E+ RP+ GYEPVSSTLWRQREEYCARLIQ
Sbjct: 1885 VDILDALTKDFFARKGNPIEETGEIGEIAARPDTEGYEPVSSTLWRQREEYCARLIQ 1941
>UniRef50_P35500 Cluster: Sodium channel protein para; n=55;
Arthropoda|Rep: Sodium channel protein para - Drosophila
melanogaster (Fruit fly)
Length = 2131
Score = 1758 bits (4358), Expect = 0.0
Identities = 870/1114 (78%), Positives = 924/1114 (82%), Gaps = 56/1114 (5%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+S LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY
Sbjct: 908 LRSFRLLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYH 967
Query: 887 DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVSCIPFFLATVVIX 946
D+ DRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCM VGDVSCIPFFLATVVI
Sbjct: 968 DHKDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMYVGDVSCIPFFLATVVIG 1027
Query: 947 XXXXXXXXXXXXXXXXXXXXXXTPTADQDTNKIAEAFNRISRFIDWIKRNVADFLKLLKN 1006
PTAD DTNKIAEAFNRI RF W+KRN+AD KL++N
Sbjct: 1028 NLVVLNLFLALLLSNFGSSSLSAPTADNDTNKIAEAFNRIGRFKSWVKRNIADCFKLIRN 1087
Query: 1007 KLTNQIAIH-----------------------APERVDNELELGTD--LDDAVLYKDKKL 1041
KLTNQI+ + E DNELELG D L D ++ K K
Sbjct: 1088 KLTNQISDQPSGERTNQISWIWSEGKGVCRCISAEHGDNELELGHDEILADGLIKKGIKE 1147
Query: 1042 KDQVEVAIGDGMEFTIPGD---NKYKKGKILMNNINAITDNHRDNRLDCELNHHGYPIQD 1098
+ Q+EVAIGDGMEFTI GD NK KK K L N D
Sbjct: 1148 QTQLEVAIGDGMEFTIHGDMKNNKPKKSKYLNN------------------------ATD 1183
Query: 1099 DDTISQKSYGSHKIRSFKDESHKGSADTIDGEEKKDASXXXXXXXXXXXXXXXXXXXXGT 1158
DDT S SYGSHK R FKDESHKGSA+T++GEEK+DAS G
Sbjct: 1184 DDTASINSYGSHKNRPFKDESHKGSAETMEGEEKRDASKEDLGLDEELDEEGECEE--GP 1241
Query: 1159 LGKTDIKVGADEDVVDDTPADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENT 1218
L I DED++D+ PADCCP+ Y+KFP LAGDDDSPFWQGWG LRLKTF+LIEN
Sbjct: 1242 LDGDIIIHAHDEDILDEYPADCCPDSYYKKFPILAGDDDSPFWQGWGNLRLKTFQLIENK 1301
Query: 1219 YFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQK 1278
YFETAVITMIL+SSLALALEDVHLP RPILQDILYYMDRIFTVIFF+EMLIKWLALGF+
Sbjct: 1302 YFETAVITMILMSSLALALEDVHLPQRPILQDILYYMDRIFTVIFFLEMLIKWLALGFKV 1361
Query: 1279 YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVN 1338
YFTNAWCWLDF+IVMVSLINFVA+L GAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVN
Sbjct: 1362 YFTNAWCWLDFVIVMVSLINFVASLVGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVN 1421
Query: 1339 ALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLE 1398
ALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKC DMN T LSHEIIP++NAC E
Sbjct: 1422 ALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCEDMNGTKLSHEIIPNRNACESE 1481
Query: 1399 NYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXX 1458
NYTW NS MNFDHVG AYLCLFQVATFKGWIQIMNDAIDSREV +QPIRETNIYMYLY
Sbjct: 1482 NYTWVNSAMNFDHVGNAYLCLFQVATFKGWIQIMNDAIDSREVDKQPIRETNIYMYLYFV 1541
Query: 1459 XXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAI 1518
TLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAI
Sbjct: 1542 FFIIFGSFFTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAI 1601
Query: 1519 PRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVI 1578
PRPRWRPQAIVFEIVTDKKFD+IIMLFIGLNM TMTLD Y S+T++AVLDYLN IF+VI
Sbjct: 1602 PRPRWRPQAIVFEIVTDKKFDIIIMLFIGLNMFTMTLDRYDASDTYNAVLDYLNAIFVVI 1661
Query: 1579 FSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKV 1638
FSSECLLKIFALRYHYF+EPWNLFD VVV+ SIL LVLSDIIEKYFVSPTLLRVVRVAKV
Sbjct: 1662 FSSECLLKIFALRYHYFIEPWNLFDVVVVILSILGLVLSDIIEKYFVSPTLLRVVRVAKV 1721
Query: 1639 GRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDD 1698
GRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVK+K G++D
Sbjct: 1722 GRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKEKSGIND 1781
Query: 1699 VYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLL 1758
VYNFKTF QSMILLFQMSTSAGWDGVLD IINEE CD PDN++G PGNCGSAT+GIT+LL
Sbjct: 1782 VYNFKTFGQSMILLFQMSTSAGWDGVLDAIINEEACDPPDNDKGYPGNCGSATVGITFLL 1841
Query: 1759 SYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQ 1818
SYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQ+FDP+G+QYIRYDQ
Sbjct: 1842 SYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQQFDPEGTQYIRYDQ 1901
Query: 1819 LSDFLDVLEPPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTKDFFARKGNPIEETG 1878
LS+FLDVLEPPLQIHKPNKYKIISMDIPICRGD+M+CVDILDALTKDFFARKGNPIEETG
Sbjct: 1902 LSEFLDVLEPPLQIHKPNKYKIISMDIPICRGDLMYCVDILDALTKDFFARKGNPIEETG 1961
Query: 1879 DL-EV-GRPEEAGYEPVSSTLWRQREEYCARLIQ 1910
++ E+ RP+ GYEPVSSTLWRQREEYCARLIQ
Sbjct: 1962 EIGEIAARPDTEGYEPVSSTLWRQREEYCARLIQ 1995
Score = 1129 bits (2796), Expect = 0.0
Identities = 576/865 (66%), Positives = 642/865 (74%), Gaps = 43/865 (4%)
Query: 1 MSEDLDSISEEERSLFRPFTRESLXXXXXXXXXXXXKQKELEKKRAEGEV---------- 50
M+ED DSISEEERSLFRPFTRESL KQKELE+KRAEGEV
Sbjct: 1 MTEDSDSISEEERSLFRPFTRESLVQIEQRIAAEHEKQKELERKRAEGEVPQYGRKKKQK 60
Query: 51 --RYXXXXXXXGPQPDATLEQGLPLPVRMQGSFPLELASTPLEDIDPFYHNQTTFVVISK 108
RY GPQPD TLEQG+P+PVR+QGSFP ELASTPLEDIDP+Y N TFVV+SK
Sbjct: 61 EIRYDDEDEDEGPQPDPTLEQGVPIPVRLQGSFPPELASTPLEDIDPYYSNVLTFVVVSK 120
Query: 109 GKDIFRFSATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVES 168
GKDIFRFSA+ A+W+LDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVES
Sbjct: 121 GKDIFRFSASKAMWMLDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVES 180
Query: 169 TEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALR 228
TEVIFTGIYTFESAVKVMARGFIL PFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALR
Sbjct: 181 TEVIFTGIYTFESAVKVMARGFILCPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALR 240
Query: 229 TFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQK 288
TFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQK
Sbjct: 241 TFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQK 300
Query: 289 CVKVFPEDGSWGNLTDENWERFCQNETNWYG--EGGDYPLCGNSSGAGQCEPGYVCLQGF 346
C+K FP DGSWGNLTDENW+ +N +NWY EG +PLCGN SGAGQC+ YVCLQGF
Sbjct: 301 CIKKFPLDGSWGNLTDENWDYHNRNSSNWYSEDEGISFPLCGNISGAGQCDDDYVCLQGF 360
Query: 347 GPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYL 395
GPNPNYGYTSFD+FGWAFLSAFRLMTQD+WE+LYQ LFF+VIIFLGSFYL
Sbjct: 361 GPNPNYGYTSFDSFGWAFLSAFRLMTQDFWEDLYQLVLRAAGPWHMLFFIVIIFLGSFYL 420
Query: 396 VNLILAIVAMSYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 455
VNLILAIVAMSY
Sbjct: 421 VNLILAIVAMSYDELQKKAEEEEAAEEEAIREAEEAAAAKAAKLEERANAQAQAAADAAA 480
Query: 456 XXXXXX--XXXKSPSDFSCQSYELFVNQERGNQDDNTRERMSLRSDPFQDSVSTQPAHKP 513
KSP+ +SC SYELFV E+GN DDN +E+MS+RS + + +P
Sbjct: 481 AEEAALHPEMAKSPT-YSCISYELFVGGEKGN-DDNNKEKMSIRSVEVESESVSVIQRQP 538
Query: 514 TATDTHDSARRPRKVSMASLSLPGSPFNLRRGSRGSHQMALXXXXXXXXXXXXXXXXLVL 573
T H A + RKVS SLSLPGSPFN+RRGSR SH+ + LVL
Sbjct: 539 APTTAH-QATKVRKVSTTSLSLPGSPFNIRRGSRSSHKYTIRNGRGRFGIPGSDRKPLVL 597
Query: 574 STYLDAQEHLPYADDSNAVTPMSEENGAIIIPVYYANLGSRHSSYTSHQSRLSYTSHGDL 633
STY DAQ+HLPYADDSNAVTPMSEENGAII+PVYY NLGSRHSSYTSHQSR+SYTSHGDL
Sbjct: 598 STYQDAQQHLPYADDSNAVTPMSEENGAIIVPVYYGNLGSRHSSYTSHQSRISYTSHGDL 657
Query: 634 LG-----GGKAQTKEARLRGRSASRNHSVTSQPHAYPLPRQDSSLASRPLREYEVSTTEC 688
LG G TKE++LR R+ +RN SV + + L R+YE+ EC
Sbjct: 658 LGGMAVMGVSTMTKESKLRNRN-TRNQSVGATNGGTTCLDTNHKLDH---RDYEIG-LEC 712
Query: 689 TDEAGKVLKPSSDNPFIESSQQPNVVDMRDVMVLNEIIEQ-AGRQSRASELNVSVYYFPT 747
TDEAGK+ DNPFIE Q VVDM+DVMVLN+IIEQ AGR SRAS+ VSVYYFPT
Sbjct: 713 TDEAGKI--KHHDNPFIEPVQTQTVVDMKDVMVLNDIIEQAAGRHSRASDRGVSVYYFPT 770
Query: 748 AEDDEDGPTFKEKLLDCLMKGIDFFCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVV 807
+DDEDGPTFK+K L+ ++KGID FCVWDCCW+WL+FQ++V+L+VFDPFVELFITLCIVV
Sbjct: 771 EDDDEDGPTFKDKALEVILKGIDVFCVWDCCWVWLKFQEWVSLIVFDPFVELFITLCIVV 830
Query: 808 NTLFMALDHHNMDKDMDKALKSGNY 832
NT+FMA+DHH+M+K+M++ LKSGNY
Sbjct: 831 NTMFMAMDHHDMNKEMERVLKSGNY 855
Score = 96.3 bits (229), Expect = 8e-18
Identities = 75/282 (26%), Positives = 139/282 (49%), Gaps = 37/282 (13%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR 1591
IV D ++ I L I +N + M +DH+ ++ VL N F F+ E +K+ A+
Sbjct: 814 IVFDPFVELFITLCIVVNTMFMAMDHHDMNKEMERVLKSGNYFFTATFAIEATMKLMAMS 873
Query: 1592 -YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
+YF E WN+FDF++V S+L L L + L V+R ++ RV +L K
Sbjct: 874 PKYYFQEGWNIFDFIIVALSLLELGLEGVQG--------LSVLRSFRLLRVFKLAKSWPT 925
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF---MH-VKDKGGLDDV--YNFKT 1704
+ L+ + ++ AL N+ +L +++FIFA+ GM F H KD+ D+ +NF
Sbjct: 926 LNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYHDHKDRFPDGDLPRWNFTD 985
Query: 1705 FVQSMILLFQMSTSAGWDGVLDGI-INEEECDLPDNERGSPGNCGSATIGITYLLSYLVI 1763
F+ S +++F++ + + D + + + C I + L+ +VI
Sbjct: 986 FMHSFMIVFRVLCGEWIESMWDCMYVGDVSC-------------------IPFFLATVVI 1026
Query: 1764 SFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQR 1805
L+V+N+++A++L N+ ++ + D+D + E + R
Sbjct: 1027 GNLVVLNLFLALLLSNFGSSS--LSAPTADNDTNKIAEAFNR 1066
Score = 79.8 bits (188), Expect = 7e-13
Identities = 70/292 (23%), Positives = 140/292 (47%), Gaps = 40/292 (13%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIM-----PTTPTVEST----EVIFTGIYTFE 180
+R ++ + F +IT IL++ + + + P P ++ + IFT I+ E
Sbjct: 1290 LRLKTFQLIENKYFETAVITMILMSSLALALEDVHLPQRPILQDILYYMDRIFTVIFFLE 1349
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALA---YVTMGIDLGNLAALRTFRVLRALK 237
+K +A GF + Y +AW WLDFV++ ++ +V + G + A +T R LRAL+
Sbjct: 1350 MLIKWLALGFKV----YFTNAWCWLDFVIVMVSLINFVASLVGAGGIQAFKTMRTLRALR 1405
Query: 238 ---TVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFP 294
++ + G++ +V A+++++ ++ +V+++ + +FA+MG+Q++ G KC +
Sbjct: 1406 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYF-KCEDMNG 1464
Query: 295 EDGSWGNLTDENWERFCQNET-NWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYG 353
S + + N C++E W ++ GN+ Y+CL +
Sbjct: 1465 TKLSHEIIPNRN---ACESENYTWVNSAMNFDHVGNA---------YLCLFQVATFKGWI 1512
Query: 354 YTSFDTFGWAFLSAFRLMTQDYWE-NLYQ-LFFVVIIFLGSFYLVNLILAIV 403
D + + + Q E N+Y L+FV I GSF+ +NL + ++
Sbjct: 1513 QIMNDA-----IDSREVDKQPIRETNIYMYLYFVFFIIFGSFFTLNLFIGVI 1559
Score = 77.0 bits (181), Expect = 5e-12
Identities = 60/207 (28%), Positives = 107/207 (51%), Gaps = 27/207 (13%)
Query: 89 PLEDID---PFYHNQTTFVVISKGKDIFRFSATNALWILDPFNPIRRVAIYILVHPLFSL 145
P ED D P + ++ V++ KG D+F + W+ F V++ I+ P L
Sbjct: 769 PTEDDDEDGPTFKDKALEVIL-KGIDVF--CVWDCCWVWLKFQ--EWVSL-IVFDPFVEL 822
Query: 146 FIITTILVNCILMIMP-------TTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYL 198
FI I+VN + M M ++S FT + E+ +K+MA + P Y
Sbjct: 823 FITLCIVVNTMFMAMDHHDMNKEMERVLKSGNYFFTATFAIEATMKLMA----MSPKYYF 878
Query: 199 RDAWNWLDFVVIALAYVTMGID-LGNLAALRTFRVLRALKTVAIVPGLK---TIVGAVIE 254
++ WN DF+++AL+ + +G++ + L+ LR+FR+LR K P L +I+G +
Sbjct: 879 QEGWNIFDFIIVALSLLELGLEGVQGLSVLRSFRLLRVFKLAKSWPTLNLLISIMGRTMG 938
Query: 255 SVKNLRDVIILTMFSLSVFALMGLQIY 281
++ NL V+ + +F +FA+MG+Q++
Sbjct: 939 ALGNLTFVLCIIIF---IFAVMGMQLF 962
Score = 72.1 bits (169), Expect = 1e-10
Identities = 45/176 (25%), Positives = 95/176 (53%), Gaps = 20/176 (11%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+R ++ + F +IT IL++ + + + P P ++ + IFT I+ E
Sbjct: 142 IRRVAIYILVHPLFSLFIITTILVNCILMIM-----PTTPTVEST----EVIFTGIYTFE 192
Query: 1267 MLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALR 1322
+K +A GF Y +AW WLDF+++ ++ + L G + A +T R LRAL+
Sbjct: 193 SAVKVMARGFILCPFTYLRDAWNWLDFVVIALAYVTMGIDL---GNLAALRTFRVLRALK 249
Query: 1323 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYF-KCV 1377
++ + G++ +V A+++++ ++ +V+++ + +FA+MG+Q++ G KC+
Sbjct: 250 ---TVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCI 302
Score = 70.5 bits (165), Expect = 4e-10
Identities = 41/160 (25%), Positives = 81/160 (50%), Gaps = 7/160 (4%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
++ + + E + I+++++ +A++ H ++ +L + FT F IE +K +A
Sbjct: 814 IVFDPFVELFITLCIVVNTMFMAMD--HHDMNKEMERVLKSGNYFFTATFAIEATMKLMA 871
Query: 1274 LGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGM 1333
+ + YF W DFIIV +SL+ G G+Q +R+ R LR + +
Sbjct: 872 MSPKYYFQEGWNIFDFIIVALSLLEL-----GLEGVQGLSVLRSFRLLRVFKLAKSWPTL 926
Query: 1334 RVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
++++ + + + ++ N+ V I IFA+MG+QLF Y
Sbjct: 927 NLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY 966
Score = 43.2 bits (97), Expect = 0.074
Identities = 31/123 (25%), Positives = 62/123 (50%), Gaps = 14/123 (11%)
Query: 1573 MIFIVIFSSECLLKIFA-----LRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSP 1627
+IF I++ E +K+ A + Y + WN DFVV+ + +++ + D+
Sbjct: 183 VIFTGIYTFESAVKVMARGFILCPFTYLRDAWNWLDFVVIALAYVTMGI-DLGN------ 235
Query: 1628 TLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
L +R +V R L+ V G++T++ A+ S+ L ++ +L + +FA+ G+ +
Sbjct: 236 --LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 293
Query: 1688 MHV 1690
M V
Sbjct: 294 MGV 296
Score = 41.1 bits (92), Expect = 0.30
Identities = 30/146 (20%), Positives = 72/146 (49%), Gaps = 10/146 (6%)
Query: 792 VFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISI 851
+FD V + L +V++ + ++ + + + + ++ RV +L K + L+
Sbjct: 1684 LFDVVVVILSILGLVLSDI---IEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFA 1740
Query: 852 MGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMI 911
+ ++ AL N+ +L +++FIFA+ GM F + ++ D+ +NF F S ++
Sbjct: 1741 LAMSLPALFNICLLLFLVMFIFAIFGMSFF----MHVKEKSGINDV--YNFKTFGQSMIL 1794
Query: 912 VFRVLCGEWIESMWDCMLVGDVSCIP 937
+F++ + + D ++ + +C P
Sbjct: 1795 LFQMSTSAGWDGVLDA-IINEEACDP 1819
Score = 40.7 bits (91), Expect = 0.40
Identities = 33/124 (26%), Positives = 62/124 (50%), Gaps = 18/124 (14%)
Query: 172 IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN-------- 223
IF I++ E +K+ F L+ + Y + WN D VV+ L+ +G+ L +
Sbjct: 1657 IFVVIFSSECLLKI----FALR-YHYFIEPWNLFDVVVVILS--ILGLVLSDIIEKYFVS 1709
Query: 224 ---LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
L +R +V R L+ V G++T++ A+ S+ L ++ +L + +FA+ G+
Sbjct: 1710 PTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSF 1769
Query: 281 YMGV 284
+M V
Sbjct: 1770 FMHV 1773
>UniRef50_Q67FT1 Cluster: Voltage-gated sodium channel protein; n=1;
Mesobuthus martensii|Rep: Voltage-gated sodium channel
protein - Mesobuthus martensii (Manchurian scorpion)
(Buthus martensii)
Length = 1871
Score = 1314 bits (3256), Expect = 0.0
Identities = 662/1126 (58%), Positives = 806/1126 (71%), Gaps = 44/1126 (3%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+S LRVFKLAKSWPTLNLLISIMG+T+GALGNLTFVL IIIFIFAVMGMQLFG+ Y+
Sbjct: 696 LRSFRLLRVFKLAKSWPTLNLLISIMGKTVGALGNLTFVLGIIIFIFAVMGMQLFGEKYI 755
Query: 887 DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVSCIPFFLATVVIX 946
+ FPD +PRWNF DFMHSFMIVFRVLCGEWIESMW MLV + C+PFFL+TV+I
Sbjct: 756 ENKHVFPDNAVPRWNFVDFMHSFMIVFRVLCGEWIESMWGRMLVAEWPCVPFFLSTVIIG 815
Query: 947 XXXXXXXXXXXXXXXXXXXXXXTPTADQ-DTNKIAEAFNRISRFIDWIKRNVADFLKLLK 1005
+ + DT K+ EAF RI R I+W+K LK L+
Sbjct: 816 NLVVLNLFPALLLSSFGAANLSMASPESADTKKLQEAFERIGRAINWVKICFLRILKNLR 875
Query: 1006 NKLTNQIAIHAPE-RVDNE-LELGTDL--DDAVLYKDKKLKDQV---EVAIGDGMEFTIP 1058
K NQI + R D E +G ++ D V K+KK ++ EV +GDG+E +I
Sbjct: 876 PKTRNQIGDQTTDIREDLEDATIGREMLVDGQVKMKEKKSPKEITDLEVVVGDGLEISIQ 935
Query: 1059 GDNKYKKGKILMNNINAITDNH-----------------RDNRLDCE-LNHHGYPIQDDD 1100
G+ + K+ N + +H +DN+ E + YP +DDD
Sbjct: 936 GNGQAIPIKMANNTKTLVNSSHMSAKVELKEKEKEKFKEKDNKEKDEGFGNKVYPQKDDD 995
Query: 1101 TISQKSYGSHKIRSFKDESHKG-------------SADTIDGEEKKDASXXXXXXXXXXX 1147
+S KS + ++ KD KG S EEKKDAS
Sbjct: 996 DVSNKSINN--VKDLKDNIEKGIPNNKPSKEESQISLPEGSQEEKKDASKDDVINEGGFL 1053
Query: 1148 XXXXXXXXXGTLGKTDIKVGADEDVVDDTPADCCPEQCYQKFPFLAGDDDSPFWQGWGTL 1207
+ + + + ++ + P+DC P++CYQ FPF G+++S FW+ + T+
Sbjct: 1054 KDEDILEEDAEIEGDNADDESSKIIIPEYPSDCFPDKCYQHFPFCLGNEESKFWRHYTTI 1113
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEM 1267
R K++ L+EN YFET +I MIL+SSLALALEDV+L R L DIL YMD+IFT++FF EM
Sbjct: 1114 RGKSYTLVENKYFETLIIFMILVSSLALALEDVNLKKRRWLMDILQYMDKIFTILFFFEM 1173
Query: 1268 LIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAM 1327
LIKWLA GF+KYFTNAWCWLDF+IV+VSL N +L G I AFKTMRTLRALRPLRAM
Sbjct: 1174 LIKWLAFGFKKYFTNAWCWLDFVIVLVSLFNLAVSLMGGSDISAFKTMRTLRALRPLRAM 1233
Query: 1328 SRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHE 1387
SR++GMRVVVNALVQAIP+IFNVLLVCLIFWLIF+IMGVQLFAGK+ C D + +
Sbjct: 1234 SRLEGMRVVVNALVQAIPAIFNVLLVCLIFWLIFSIMGVQLFAGKFRYCADKDGNRFNSS 1293
Query: 1388 IIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSRE-VGRQPI 1446
+P+K+ C L N+TWEN +N D+V AYL LFQVATFKGWI IM++AID+++ QP
Sbjct: 1294 TVPNKSVCCLNNFTWENPKINSDNVLNAYLALFQVATFKGWIDIMSNAIDTKQNEDEQPE 1353
Query: 1447 RETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAM 1506
E N YMYLY TLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAM
Sbjct: 1354 YEVNRYMYLYFVLFIIIGSFFTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAM 1413
Query: 1507 KKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSA 1566
KKMG KKP KAIPRPR++ QA+VF+++T+ KFDM I+LFIGLNML M ++HY Q+ TF
Sbjct: 1414 KKMGEKKPAKAIPRPRFKLQAVVFDLITNTKFDMAIVLFIGLNMLVMAMEHYHQTPTFDD 1473
Query: 1567 VLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVS 1626
+L+ LN+ FI IF++EC+LK+FALR++YF EPWN+FD VVV SIL + + D+I YFVS
Sbjct: 1474 ILERLNIFFIAIFTTECVLKMFALRWYYFKEPWNVFDCVVVTLSILGIAIKDLIASYFVS 1533
Query: 1627 PTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSF 1686
PTLLRVVRV KVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFI+AIFGMSF
Sbjct: 1534 PTLLRVVRVVKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIYAIFGMSF 1593
Query: 1687 FMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGN 1746
FM VK + G+DD +NF+TF QSMILLFQMSTSAGWDGVL GI+++ +C + G G+
Sbjct: 1594 FMTVKHRAGIDDNFNFETFGQSMILLFQMSTSAGWDGVLLGIMDDSDCVQGSEDEGIEGD 1653
Query: 1747 CGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRF 1806
CG + + YL+SYL++SFLI+INMYIAVILENYSQATEDVQEGLT DDYDMYYEIWQ++
Sbjct: 1654 CGKPGVAVAYLISYLIVSFLIIINMYIAVILENYSQATEDVQEGLTADDYDMYYEIWQKY 1713
Query: 1807 DPDGSQYIRYDQLSDFLDVLEPPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTKDF 1866
DP+G+QYI+Y+ LSDFLD LE PLQI KPNKYKII MDI IC+GD+M+CVDILDALTKDF
Sbjct: 1714 DPEGTQYIKYEDLSDFLDALEEPLQIEKPNKYKIIDMDITICKGDLMYCVDILDALTKDF 1773
Query: 1867 FARKGNPIEETGDL-EVG-RPEEAGYEPVSSTLWRQREEYCARLIQ 1910
FARKG IEE+ +L EV R + GYEP+SST +RQ+EEY AR+IQ
Sbjct: 1774 FARKGTAIEESAELGEVAPRKDVEGYEPISSTRFRQQEEYNARVIQ 1819
Score = 516 bits (1274), Expect = e-144
Identities = 254/419 (60%), Positives = 306/419 (73%), Gaps = 18/419 (4%)
Query: 1 MSEDLDSISEEERSLFRPFTRESLXXXXXXXXXXXXKQKELEKKRAEGEVRYXXXXXXXG 60
MS D S EE FRPFTRESL ++KE +K+ EG+ +
Sbjct: 1 MSSDEQS-EEEVLPAFRPFTRESLAAIEARIAEAESRKKESLQKKGEGDDEHYGTYQPEV 59
Query: 61 PQPDATLEQGLPLPVRMQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNA 120
+ D LE GLPLP ++ FP EL +TP+E +D FY N+ TF+VISKGKDIFRFSATNA
Sbjct: 60 AEADPQLEAGLPLPKYLEREFPPELLATPIEGLDKFYENKRTFIVISKGKDIFRFSATNA 119
Query: 121 LWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFE 180
+WILDPFNPIRR AI ILVHP FS +I TILVNC+LM + E +FT IYT E
Sbjct: 120 MWILDPFNPIRRAAISILVHPAFSFLVIVTILVNCVLMTQTNVTHEKELERLFTAIYTIE 179
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVA 240
S +K ARGFIL+ FTYLRD WNWLDFVVI+LAY+TMG++LGNL+ALRTFRVLRALKTVA
Sbjct: 180 SCIKATARGFILEQFTYLRDPWNWLDFVVISLAYITMGVELGNLSALRTFRVLRALKTVA 239
Query: 241 IVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWG 300
++PGLKTIVGAVIESVKNL+DVIILT+FSLS+FAL+GLQ+YMGVL QKC+ P
Sbjct: 240 VIPGLKTIVGAVIESVKNLKDVIILTVFSLSLFALLGLQMYMGVLMQKCIVEAPP----- 294
Query: 301 NLTDENWERFCQNETNWY-GEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDT 359
N T E + +N++NWY G+Y +CGN+SGA QC GY+CL +GPNPN+G+T+FDT
Sbjct: 295 NTTYEEKKVHYRNQSNWYLDSAGEYFICGNASGARQCPEGYICLSNYGPNPNHGFTNFDT 354
Query: 360 FGWAFLSAFRLMTQDYWENLYQL-----------FFVVIIFLGSFYLVNLILAIVAMSY 407
F WAFL++FRLMTQD+WE LYQ+ FF+VIIFLGSFYL+NLILAIVAMSY
Sbjct: 355 FYWAFLASFRLMTQDFWEGLYQMVLRTAGPWHICFFIVIIFLGSFYLLNLILAIVAMSY 413
Score = 136 bits (329), Expect = 6e-30
Identities = 69/133 (51%), Positives = 91/133 (68%), Gaps = 11/133 (8%)
Query: 701 DNPFIESSQQPNVVDMRDVMVLNEIIEQA-GRQSRASELNVSVYYFPTAEDDEDGPTFKE 759
D+PFI+ +Q + DM+DVMVLN+II+QA GRQSR S + E+ FKE
Sbjct: 519 DSPFIDPQRQTEL-DMKDVMVLNDIIDQAAGRQSRESGRE---------REPEEKEKFKE 568
Query: 760 KLLDCLMKGIDFFCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNM 819
K ++ ID FCVWDCC WL QK V ++VFDPF+ELFITL I+VNTLFM+++H +M
Sbjct: 569 KCFKNCLRFIDIFCVWDCCNCWLYIQKIVNIIVFDPFMELFITLAIIVNTLFMSIEHADM 628
Query: 820 DKDMDKALKSGNY 832
DK + + LK+GNY
Sbjct: 629 DKSLQEFLKNGNY 641
Score = 90.2 bits (214), Expect = 5e-16
Identities = 73/267 (27%), Positives = 134/267 (50%), Gaps = 35/267 (13%)
Query: 1526 QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLL 1585
Q IV IV D ++ I L I +N L M+++H ++ L N F F+ E ++
Sbjct: 594 QKIVNIIVFDPFMELFITLAIIVNTLFMSIEHADMDKSLQEFLKNGNYFFTATFAIEAVM 653
Query: 1586 KIFALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRL 1644
K+ AL +YF E WN+FDF++V+ S++ L + VS L V+R ++ RV +L
Sbjct: 654 KLVALSPKYYFKEGWNIFDFLIVVLSLVELCGEN------VSLPGLSVLRSFRLLRVFKL 707
Query: 1645 VKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF--MHVKDKGGLDD---- 1698
K + L+ + ++ AL N+ +L +++FIFA+ GM F ++++K D
Sbjct: 708 AKSWPTLNLLISIMGKTVGALGNLTFVLGIIIFIFAVMGMQLFGEKYIENKHVFPDNAVP 767
Query: 1699 VYNFKTFVQSMILLFQMSTSAGWDGVLDG--IINEEECDLPDNERGSPGNCGSATIGITY 1756
+NF F+ S +++F++ W + G ++ E C + +
Sbjct: 768 RWNFVDFMHSFMIVFRV-LCGEWIESMWGRMLVAEWPC-------------------VPF 807
Query: 1757 LLSYLVISFLIVINMYIAVILENYSQA 1783
LS ++I L+V+N++ A++L ++ A
Sbjct: 808 FLSTVIIGNLVVLNLFPALLLSSFGAA 834
Score = 75.8 bits (178), Expect = 1e-11
Identities = 45/163 (27%), Positives = 85/163 (52%), Gaps = 7/163 (4%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
++ + + E + I++++L +++E H LQ+ L + FT F IE ++K +A
Sbjct: 600 IVFDPFMELFITLAIIVNTLFMSIE--HADMDKSLQEFLKNGNYFFTATFAIEAVMKLVA 657
Query: 1274 LGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAG-GIQAFKTMRTLRALRPLRAMSRMQG 1332
L + YF W DF+IV++SL+ LCG + +R+ R LR +
Sbjct: 658 LSPKYYFKEGWNIFDFLIVVLSLVE----LCGENVSLPGLSVLRSFRLLRVFKLAKSWPT 713
Query: 1333 MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK 1375
+ ++++ + + + ++ N+ V I IFA+MG+QLF KY +
Sbjct: 714 LNLLISIMGKTVGALGNLTFVLGIIIFIFAVMGMQLFGEKYIE 756
Score = 74.5 bits (175), Expect = 3e-11
Identities = 61/247 (24%), Positives = 121/247 (48%), Gaps = 42/247 (17%)
Query: 172 IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM------GIDLGNLA 225
IFT ++ FE +K +A GF Y +AW WLDFV++ ++ + G D+
Sbjct: 1164 IFTILFFFEMLIKWLAFGFK----KYFTNAWCWLDFVIVLVSLFNLAVSLMGGSDISAFK 1219
Query: 226 ALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVL 285
+RT R LR L+ ++ + G++ +V A+++++ + +V+++ + +F++MG+Q++ G
Sbjct: 1220 TMRTLRALRPLRAMSRLEGMRVVVNALVQAIPAIFNVLLVCLIFWLIFSIMGVQLFAGKF 1279
Query: 286 TQKCVKVFPEDGS-WGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQ 344
+ C +DG+ + + T N C N W + P + + Y+ L
Sbjct: 1280 -RYCA---DKDGNRFNSSTVPNKSVCCLNNFTW-----ENPKINSDNVLN----AYLAL- 1325
Query: 345 GFGPNPNYGYTSFDTFGWAFLSAFRLMTQ-------DYWENLYQ-LFFVVIIFLGSFYLV 396
+ +F GW + + + T+ +Y N Y L+FV+ I +GSF+ +
Sbjct: 1326 -------FQVATFK--GWIDIMSNAIDTKQNEDEQPEYEVNRYMYLYFVLFIIIGSFFTL 1376
Query: 397 NLILAIV 403
NL + ++
Sbjct: 1377 NLFIGVI 1383
Score = 73.7 bits (173), Expect = 5e-11
Identities = 38/128 (29%), Positives = 75/128 (58%), Gaps = 11/128 (8%)
Query: 1255 MDRIFTVIFFIEMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQ 1310
++R+FT I+ IE IK A GF Y + W WLDF+++ ++ I L G +
Sbjct: 168 LERLFTAIYTIESCIKATARGFILEQFTYLRDPWNWLDFVVISLAYITMGVEL---GNLS 224
Query: 1311 AFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
A +T R LRAL+ + + G++ +V A+++++ ++ +V+++ + +FA++G+Q++
Sbjct: 225 ALRTFRVLRALKTVAVIP---GLKTIVGAVIESVKNLKDVIILTVFSLSLFALLGLQMYM 281
Query: 1371 GKYF-KCV 1377
G KC+
Sbjct: 282 GVLMQKCI 289
Score = 73.3 bits (172), Expect = 6e-11
Identities = 47/173 (27%), Positives = 89/173 (51%), Gaps = 7/173 (4%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVEST-EVIFTGIYTFES--AVKVM 186
I+++ I+ P LFI I+VN + M + +S E + G Y F + A++ +
Sbjct: 593 IQKIVNIIVFDPFMELFITLAIIVNTLFMSIEHADMDKSLQEFLKNGNYFFTATFAIEAV 652
Query: 187 ARGFILQPFTYLRDAWNWLDFVVIALAYVTM---GIDLGNLAALRTFRVLRALKTVAIVP 243
+ L P Y ++ WN DF+++ L+ V + + L L+ LR+FR+LR K P
Sbjct: 653 MKLVALSPKYYFKEGWNIFDFLIVVLSLVELCGENVSLPGLSVLRSFRLLRVFKLAKSWP 712
Query: 244 GLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPED 296
L ++ + ++V L ++ + + +FA+MG+Q++ G + VFP++
Sbjct: 713 TLNLLISIMGKTVGALGNLTFVLGIIIFIFAVMGMQLF-GEKYIENKHVFPDN 764
Score = 52.4 bits (120), Expect = 1e-04
Identities = 43/171 (25%), Positives = 83/171 (48%), Gaps = 21/171 (12%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMP---TTPT----VESTEVIFTGIYTFESA 182
++ V ++ + F + I+ I +N ++M M TPT +E + F I+T E
Sbjct: 1432 LQAVVFDLITNTKFDMAIVLFIGLNMLVMAMEHYHQTPTFDDILERLNIFFIAIFTTECV 1491
Query: 183 VKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DL--------GNLAALRTFRVL 233
+K+ A + Y ++ WN D VV+ L+ + + I DL L +R +V
Sbjct: 1492 LKMFALRWY-----YFKEPWNVFDCVVVTLSILGIAIKDLIASYFVSPTLLRVVRVVKVG 1546
Query: 234 RALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
R L+ V G++T++ A+ S+ L ++ +L + ++A+ G+ +M V
Sbjct: 1547 RVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIYAIFGMSFFMTV 1597
Score = 47.2 bits (107), Expect = 0.005
Identities = 41/164 (25%), Positives = 78/164 (47%), Gaps = 21/164 (12%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL- 1590
I+ F ++++ I +N + MT Q + T L+ L F I++ E +K A
Sbjct: 136 ILVHPAFSFLVIVTILVNCVLMT----QTNVTHEKELERL---FTAIYTIESCIKATARG 188
Query: 1591 ----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVK 1646
++ Y +PWN DFVV+ + +++ V L +R +V R L+ V
Sbjct: 189 FILEQFTYLRDPWNWLDFVVISLAYITM---------GVELGNLSALRTFRVLRALKTVA 239
Query: 1647 GAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHV 1690
G++T++ A+ S+ L ++ +L + +FA+ G+ +M V
Sbjct: 240 VIPGLKTIVGAVIESVKNLKDVIILTVFSLSLFALLGLQMYMGV 283
>UniRef50_Q86D77 Cluster: Sodium channel protein; n=3; Eukaryota|Rep:
Sodium channel protein - Varroa destructor (honeybee
mite)
Length = 2215
Score = 1069 bits (2646), Expect = 0.0
Identities = 508/752 (67%), Positives = 608/752 (80%), Gaps = 5/752 (0%)
Query: 1164 IKVGADEDVVDDTPADCCPEQCYQKFPFLAGDDDS-PFWQGWGTLRLKTFKLIENTYFET 1222
++ A + ++ + PADCCPE CY KF DDS P + + R + F L+EN YFET
Sbjct: 1408 LETAASDLIIPELPADCCPECCYVKFACCCIFDDSQPLFAKYKLYRSQAFALVENEYFET 1467
Query: 1223 AVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTN 1282
V+ +IL SSLALALEDV+L R L +IL MD+ FTVIFF EML+KWLA GFQKYFTN
Sbjct: 1468 IVVVLILTSSLALALEDVNLKQRQWLINILNVMDKTFTVIFFSEMLLKWLAFGFQKYFTN 1527
Query: 1283 AWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQ 1342
AWCWLDF+IV+VS+IN VA GAG IQAFKTMRTLRALRPLRA+SR QGMRVVVNALVQ
Sbjct: 1528 AWCWLDFVIVLVSVINLVATWLGAGKIQAFKTMRTLRALRPLRALSRFQGMRVVVNALVQ 1587
Query: 1343 AIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTW 1402
AIP+IFNVLLVCL+FWLIF+IMGVQ+FAG+++ CVD N++ L+ IP+K AC N+TW
Sbjct: 1588 AIPAIFNVLLVCLVFWLIFSIMGVQMFAGRFYHCVDANNSQLNSTFIPNKEACINNNFTW 1647
Query: 1403 ENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXX 1462
+N +NFD+V AYL LFQVATFKGW +IM A DSR QP E NIYMYLY
Sbjct: 1648 KNPMINFDNVLNAYLALFQVATFKGWTEIMAHATDSRGKDDQPDYEVNIYMYLYFVFFII 1707
Query: 1463 XXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPR 1522
TLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYY+AMKKMGSKKP KAIPRPR
Sbjct: 1708 FGAFFTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYSAMKKMGSKKPAKAIPRPR 1767
Query: 1523 WRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSE 1582
++ QA++F++ T++ FDM IM+FI LNM M ++HYQQS+ F ++L+ LN+ FI +F++E
Sbjct: 1768 FKLQAMIFDLTTNRMFDMAIMIFIVLNMTVMAMEHYQQSDFFESILERLNIFFIAVFTAE 1827
Query: 1583 CLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVL 1642
C+LKIFALR+HYF EPWN+FDFVVV+ SIL VL D+I YFVSPTLLRVVRV KVGRVL
Sbjct: 1828 CVLKIFALRWHYFKEPWNMFDFVVVILSILGTVLKDLIAAYFVSPTLLRVVRVVKVGRVL 1887
Query: 1643 RLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNF 1702
RLVKGA+GIRTLLFALAMSLPALFNICLLLFLVMFI+AIFGMSFFM+VK + G+D+ +NF
Sbjct: 1888 RLVKGARGIRTLLFALAMSLPALFNICLLLFLVMFIYAIFGMSFFMNVKHRYGVDENFNF 1947
Query: 1703 KTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLP--DNERGSPGNCGSATIGITYLLSY 1760
+TF QSMILLFQM TSAGW VL I++E +C+ P D + + GNC I + YL+SY
Sbjct: 1948 ETFGQSMILLFQMCTSAGWSDVLAAIMDETDCEEPTIDEDGETEGNCDKKGIAVAYLVSY 2007
Query: 1761 LVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLS 1820
L+ISFL++INMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQ+FDP G+QY+ Y LS
Sbjct: 2008 LIISFLVIINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQQFDPKGTQYLPYSHLS 2067
Query: 1821 DFLDVLEPPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTKDFFARKGNPIEETGDL 1880
+F++ LE PLQI KPNKYK+I++DIPIC+GDM++CVDILDALT+DFFARKG+ IEE +L
Sbjct: 2068 NFVNALEEPLQIPKPNKYKLIALDIPICKGDMVYCVDILDALTRDFFARKGHQIEEPPEL 2127
Query: 1881 --EVGRPEEAGYEPVSSTLWRQREEYCARLIQ 1910
+V + GYEP+SSTL RQR+EYCAR+IQ
Sbjct: 2128 TEQVIHIDRPGYEPISSTLLRQRQEYCARVIQ 2159
Score = 557 bits (1376), Expect = e-157
Identities = 276/413 (66%), Positives = 314/413 (76%), Gaps = 18/413 (4%)
Query: 8 ISEEERSLFRPFTRESLXXXXXXXXXXXXKQKELEKKRAEG-EVRYXXXXXXXGPQPDAT 66
+ +E +S+FRPFTRESL K+ +LEK R EG E P PD
Sbjct: 56 LGDEPQSIFRPFTRESLATQLARLAEEAAKKAQLEKMREEGIEPEPQFYHHKEAPDPDPG 115
Query: 67 LEQGLPLPVRMQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNALWILDP 126
LE G PLP R+ FP EL +TP+E+ID +Y N+ TF+VISKGKDIFRFS+TNALWIL P
Sbjct: 116 LEAGGPLPKRIVNDFPPELIATPVEEIDKYYENKRTFMVISKGKDIFRFSSTNALWILSP 175
Query: 127 FNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVM 186
FNPIRR+AI ILVHPLFS FII ILVNC+LM MP +E TE IFT IYTFES +K++
Sbjct: 176 FNPIRRLAICILVHPLFSFFIIVAILVNCVLMTMPANGKIEQTETIFTTIYTFESFIKIL 235
Query: 187 ARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLK 246
ARGFIL+ FTYL D WNWLDF+VI LAYVTM ++LGNL+ALRTFRVLRALKTVAIVPGLK
Sbjct: 236 ARGFILERFTYLGDPWNWLDFIVITLAYVTMFVNLGNLSALRTFRVLRALKTVAIVPGLK 295
Query: 247 TIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDEN 306
TIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCV+ P L+
Sbjct: 296 TIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVQQPP-----AGLSPPE 350
Query: 307 WERFCQNETNWYGE-GGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFL 365
W F NET+W+ + GD+PLCGN +GA QC Y+C+QG G NPNYG+T+FDTFGWAFL
Sbjct: 351 WYDFVHNETHWFKDSNGDFPLCGNGTGAKQCSADYICMQGIGENPNYGFTNFDTFGWAFL 410
Query: 366 SAFRLMTQDYWENLYQL-----------FFVVIIFLGSFYLVNLILAIVAMSY 407
SAFRLMTQDYWE+LYQ+ FFVVIIFLGSFYLVNLILAIVAMSY
Sbjct: 411 SAFRLMTQDYWESLYQMILRSAGPWHMCFFVVIIFLGSFYLVNLILAIVAMSY 463
Score = 278 bits (682), Expect = 1e-72
Identities = 178/391 (45%), Positives = 225/391 (57%), Gaps = 52/391 (13%)
Query: 465 KSPSDFSCQSYELFVNQERGNQDDNTRERMSLRSDPFQDSVSTQPAHKPTATDTHDSARR 524
KSPS++S +S + D+ R +D Q + P H + +R
Sbjct: 556 KSPSEYSMRSLDAGTGHPSVPPDERASLRSIDGADLLQHTGHGGP-HSQQQQQLYSQSRH 614
Query: 525 PR-KVSMASLSLPGSPFNLRRGSRGSHQMALXXXXXXXXXXXXX--------------XX 569
KV ASLSLPGSPFN+RRGSR S Q
Sbjct: 615 NNGKVRKASLSLPGSPFNIRRGSRSSGQWRPSGHPANGGGGAAGRRPGGGGGQPCYGGAK 674
Query: 570 XLVLSTYLDAQEHLPYADDSNAVTPMSEENGAIIIPVYYANLGSRHSSYTSHQSRLSYTS 629
L+ TY+DAQEHLP+ADDS AVTPMSE+NGAIIIP+Y SR SSYTSH SRLSYTS
Sbjct: 675 PLLRQTYVDAQEHLPFADDSAAVTPMSEDNGAIIIPLYSNLQHSRRSSYTSHSSRLSYTS 734
Query: 630 HGDLLGGGKAQTKEARLRGRSASRNHSVTSQPHAYPLPRQDSSLASRPLREYEVSTTECT 689
HG++ TKE++LR R SRN Q + Y Q++ L S +Y +S +
Sbjct: 735 HGEVY----CLTKESQLRSR--SRN----LQNYFYD---QETRLDS---EDYILSKIK-- 776
Query: 690 DEAGKVLKPSSDNPFIESSQQPNVVDMRDVMVLNEIIEQ-AGRQSRASELNVSVYYFPTA 748
+ P++E S + +VDMRDVMVLN+IIEQ AGRQS+ASE VS+YYF T
Sbjct: 777 ---------QVNKPYMEPSTRHPMVDMRDVMVLNDIIEQAAGRQSKASE-RVSIYYFSTD 826
Query: 749 EDDEDG-------PTFKEKLLDCLMKGIDFFCVWDCCWLWLEFQKYVALLVFDPFVELFI 801
++DE +KEK L +K ID FCVWDCCW W+ Q+ + L+VFDPF+ELFI
Sbjct: 827 DEDEGSLEEEDVEAKWKEKCLAGCLKCIDIFCVWDCCWCWIRAQEIIGLIVFDPFMELFI 886
Query: 802 TLCIVVNTLFMALDHHNMDKDMDKALKSGNY 832
TLCIVVNTLFMA+DHH+MD+D + L+SGNY
Sbjct: 887 TLCIVVNTLFMAMDHHDMDRDFENVLRSGNY 917
Score = 227 bits (555), Expect = 2e-57
Identities = 124/239 (51%), Positives = 141/239 (58%), Gaps = 10/239 (4%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+S LRVFKLAKSWPTLNLLISIMG+T+GALGNLTFVL IIIFIFAVMGMQLFGKNY+
Sbjct: 970 LRSFRLLRVFKLAKSWPTLNLLISIMGKTIGALGNLTFVLGIIIFIFAVMGMQLFGKNYL 1029
Query: 887 DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVSCIPFFLATVVIX 946
D FP+ +PRWNF DFMHS MIVFRVLCGEWIESMWDCM V CIPFFLATVVI
Sbjct: 1030 DNKCLFPEQQVPRWNFLDFMHSLMIVFRVLCGEWIESMWDCMWVSGWPCIPFFLATVVIG 1089
Query: 947 XXXXXXXXXXXXXXXXXXXXXXTPTADQ-DTNKIAEAFNRISRFIDWIKRNVADFLKLLK 1005
D DT K+ EA +R R WIK+ D L
Sbjct: 1090 NLVVLNLFLALLLSSFGASNLSQANPDSGDTKKLQEAIDRFHRAGRWIKKKFRDLFMLCS 1149
Query: 1006 NKLTNQIAIHAPERVDNELELGTDLDDAVLYKDKKL--KDQVEVAIGDGMEFTIPGDNK 1062
K NQI+ D DLD V+ D ++ KD + DG++ D +
Sbjct: 1150 GKQRNQIS-------DQTYAEDLDLDTGVIIMDGQVIKKDSPTPELIDGLDVGFQADKQ 1201
Score = 92.3 bits (219), Expect = 1e-16
Identities = 75/264 (28%), Positives = 131/264 (49%), Gaps = 33/264 (12%)
Query: 1524 RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSEC 1583
R Q I+ IV D ++ I L I +N L M +DH+ F VL N F F+ E
Sbjct: 868 RAQEIIGLIVFDPFMELFITLCIVVNTLFMAMDHHDMDRDFENVLRSGNYFFTATFAIEA 927
Query: 1584 LLKIFALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVL 1642
+K+ A +YF E WN+FDF++V S+L L L + L V+R ++ RV
Sbjct: 928 TMKLMAKSPKNYFKEGWNIFDFIIVALSLLELGLEGVQG--------LSVLRSFRLLRVF 979
Query: 1643 RLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF--MHVKDKGGLDDV- 1699
+L K + L+ + ++ AL N+ +L +++FIFA+ GM F ++ +K +
Sbjct: 980 KLAKSWPTLNLLISIMGKTIGALGNLTFVLGIIIFIFAVMGMQLFGKNYLDNKCLFPEQQ 1039
Query: 1700 ---YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITY 1756
+NF F+ S++++F++ + + D C G P C I +
Sbjct: 1040 VPRWNFLDFMHSLMIVFRVLCGEWIESMWD-------CMWVS---GWP--C------IPF 1081
Query: 1757 LLSYLVISFLIVINMYIAVILENY 1780
L+ +VI L+V+N+++A++L ++
Sbjct: 1082 FLATVVIGNLVVLNLFLALLLSSF 1105
Score = 79.0 bits (186), Expect = 1e-12
Identities = 48/168 (28%), Positives = 87/168 (51%), Gaps = 15/168 (8%)
Query: 137 ILVHPLFSLFIITTILVNCILMIMPTTP-------TVESTEVIFTGIYTFESAVKVMARG 189
I+ P LFI I+VN + M M + S FT + E+ +K+MA+
Sbjct: 876 IVFDPFMELFITLCIVVNTLFMAMDHHDMDRDFENVLRSGNYFFTATFAIEATMKLMAKS 935
Query: 190 FILQPFTYLRDAWNWLDFVVIALAYVTMGID-LGNLAALRTFRVLRALKTVAIVPGLKTI 248
P Y ++ WN DF+++AL+ + +G++ + L+ LR+FR+LR K P L +
Sbjct: 936 ----PKNYFKEGWNIFDFIIVALSLLELGLEGVQGLSVLRSFRLLRVFKLAKSWPTLNLL 991
Query: 249 VGAVIESVKNLRDVIILTMFSLSVFALMGLQIY-MGVLTQKCVKVFPE 295
+ + +++ L ++ + + +FA+MG+Q++ L KC +FPE
Sbjct: 992 ISIMGKTIGALGNLTFVLGIIIFIFAVMGMQLFGKNYLDNKC--LFPE 1037
Score = 74.9 bits (176), Expect = 2e-11
Identities = 42/135 (31%), Positives = 76/135 (56%), Gaps = 11/135 (8%)
Query: 1256 DRIFTVIFFIEMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQA 1311
+ IFT I+ E IK LA GF Y + W WLDFI++ ++ +V G + A
Sbjct: 219 ETIFTTIYTFESFIKILARGFILERFTYLGDPWNWLDFIVITLA---YVTMFVNLGNLSA 275
Query: 1312 FKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
+T R LRAL+ ++ + G++ +V A+++++ ++ +V+++ + +FA+MG+Q++ G
Sbjct: 276 LRTFRVLRALK---TVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 332
Query: 1372 KYF-KCVDMNHTTLS 1385
KCV LS
Sbjct: 333 VLTQKCVQQPPAGLS 347
Score = 71.7 bits (168), Expect = 2e-10
Identities = 47/166 (28%), Positives = 84/166 (50%), Gaps = 9/166 (5%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
++ + + E + I++++L +A+ D H R +++L + FT F IE +K +A
Sbjct: 876 IVFDPFMELFITLCIVVNTLFMAM-DHHDMDRDF-ENVLRSGNYFFTATFAIEATMKLMA 933
Query: 1274 LGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGM 1333
+ YF W DFIIV +SL+ G G+Q +R+ R LR + +
Sbjct: 934 KSPKNYFKEGWNIFDFIIVALSLLEL-----GLEGVQGLSVLRSFRLLRVFKLAKSWPTL 988
Query: 1334 RVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYF--KCV 1377
++++ + + I ++ N+ V I IFA+MG+QLF Y KC+
Sbjct: 989 NLLISIMGKTIGALGNLTFVLGIIIFIFAVMGMQLFGKNYLDNKCL 1034
Score = 67.7 bits (158), Expect = 3e-09
Identities = 59/238 (24%), Positives = 112/238 (47%), Gaps = 27/238 (11%)
Query: 173 FTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM---GIDLGNLAALRT 229
FT I+ E +K +A GF Y +AW WLDFV++ ++ + + + G + A +T
Sbjct: 1504 FTVIFFSEMLLKWLAFGFQ----KYFTNAWCWLDFVIVLVSVINLVATWLGAGKIQAFKT 1559
Query: 230 FRVLRALKTVAIV---PGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLT 286
R LRAL+ + + G++ +V A+++++ + +V+++ + +F++MG+Q++ G
Sbjct: 1560 MRTLRALRPLRALSRFQGMRVVVNALVQAIPAIFNVLLVCLVFWLIFSIMGVQMFAGRF- 1618
Query: 287 QKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGF 346
CV + + N E N W ++ N+ Y+ L F
Sbjct: 1619 YHCVDA--NNSQLNSTFIPNKEACINNNFTWKNPMINFDNVLNA---------YLAL--F 1665
Query: 347 GPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ-LFFVVIIFLGSFYLVNLILAIV 403
G+T + A S + DY N+Y L+FV I G+F+ +NL + ++
Sbjct: 1666 QVATFKGWT--EIMAHATDSRGKDDQPDYEVNIYMYLYFVFFIIFGAFFTLNLFIGVI 1721
Score = 55.2 bits (127), Expect = 2e-05
Identities = 41/164 (25%), Positives = 79/164 (48%), Gaps = 21/164 (12%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL- 1590
I+ F I++ I +N + MT+ + ++ IF I++ E +KI A
Sbjct: 186 ILVHPLFSFFIIVAILVNCVLMTMPA-------NGKIEQTETIFTTIYTFESFIKILARG 238
Query: 1591 ----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVK 1646
R+ Y +PWN DF+V+ + +++ FV+ L +R +V R L+ V
Sbjct: 239 FILERFTYLGDPWNWLDFIVITLAYVTM---------FVNLGNLSALRTFRVLRALKTVA 289
Query: 1647 GAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHV 1690
G++T++ A+ S+ L ++ +L + +FA+ G+ +M V
Sbjct: 290 IVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 333
Score = 49.2 bits (112), Expect = 0.001
Identities = 40/159 (25%), Positives = 78/159 (49%), Gaps = 21/159 (13%)
Query: 142 LFSLFIITTILVNCILMIMPT-------TPTVESTEVIFTGIYTFESAVKVMARGFILQP 194
+F + I+ I++N +M M +E + F ++T E +K+ F L+
Sbjct: 1782 MFDMAIMIFIVLNMTVMAMEHYQQSDFFESILERLNIFFIAVFTAECVLKI----FALR- 1836
Query: 195 FTYLRDAWNWLDFVVIALAYV-TMGIDL--------GNLAALRTFRVLRALKTVAIVPGL 245
+ Y ++ WN DFVV+ L+ + T+ DL L +R +V R L+ V G+
Sbjct: 1837 WHYFKEPWNMFDFVVVILSILGTVLKDLIAAYFVSPTLLRVVRVVKVGRVLRLVKGARGI 1896
Query: 246 KTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
+T++ A+ S+ L ++ +L + ++A+ G+ +M V
Sbjct: 1897 RTLLFALAMSLPALFNICLLLFLVMFIYAIFGMSFFMNV 1935
Score = 36.7 bits (81), Expect = 6.4
Identities = 22/82 (26%), Positives = 44/82 (53%), Gaps = 6/82 (7%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
RV +L K + L+ + ++ AL N+ +L +++FI+A+ GM F ++ R+
Sbjct: 1885 RVLRLVKGARGIRTLLFALAMSLPALFNICLLLFLVMFIYAIFGMSFF----MNVKHRY- 1939
Query: 894 DGDLPRWNFTDFMHSFMIVFRV 915
G +NF F S +++F++
Sbjct: 1940 -GVDENFNFETFGQSMILLFQM 1960
>UniRef50_Q14524 Cluster: Sodium channel protein type 5 subunit alpha;
n=79; Euteleostomi|Rep: Sodium channel protein type 5
subunit alpha - Homo sapiens (Human)
Length = 2016
Score = 979 bits (2424), Expect = 0.0
Identities = 516/1107 (46%), Positives = 691/1107 (62%), Gaps = 27/1107 (2%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+S LRVFKLAKSWPTLN LI I+G ++GALGNLT VL II+FIFAV+GMQLFGKNY
Sbjct: 807 LRSFRLLRVFKLAKSWPTLNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKNYS 866
Query: 887 DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLV-GDVSCIPFFLATVVI 945
+ D G LPRW+ DF H+F+I+FR+LCGEWIE+MWDCM V G C+ FL +VI
Sbjct: 867 ELRDS-DSGLLPRWHMMDFFHAFLIIFRILCGEWIETMWDCMEVSGQSLCLLVFLLVMVI 925
Query: 946 XXXXXXXXXXXXXXXXXXXXXXXTPTADQDTNKIAEAFNRISRFIDWIKRNVADF-LKLL 1004
P D++ N + A RI R + ++KR DF LL
Sbjct: 926 GNLVVLNLFLALLLSSFSADNLTAPDEDREMNNLQLALARIQRGLRFVKRTTWDFCCGLL 985
Query: 1005 KNKLTNQIAIHAPERVDNELELGTDLDDAVLYKDKKLKDQVEVAIGDGMEFTIPGDNKYK 1064
+++ A+ A ++ + + K + + + G+ PGD +
Sbjct: 986 RHRPQKPAALAAQGQLPSCIATPYSPPPPETEKVPPTRKETQFEEGEQPGQGTPGDPEPV 1045
Query: 1065 KGKILMNNINAITDNHRDNRLDCELNHHGYPIQDDDTISQKSYGSHKIRSFKDESHKGSA 1124
I + + D D Q+ +S G R++ S S+
Sbjct: 1046 CVPIAVAESDT-DDQEEDEENSLGTEEESSKQQESQPVSGWPRGPPDSRTWSQVSATASS 1104
Query: 1125 DTIDGEEKKDASXXXXXXXXXXXXXXXXXXXXGTLGKTDIKVGAD--EDVVD-----DTP 1177
+ + D D+ A+ E + D P
Sbjct: 1105 EAEASASQADWRQQWKAEPQAPGCGETPEDSCSEGSTADMTNTAELLEQIPDLGQDVKDP 1164
Query: 1178 ADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALAL 1237
DC E C ++ P A D + W LR + ++E+++FET +I MILLSS ALA
Sbjct: 1165 EDCFTEGCVRRCPCCAVDTTQAPGKVWWRLRKTCYHIVEHSWFETFIIFMILLSSGALAF 1224
Query: 1238 EDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLI 1297
ED++L R ++ +L Y D++FT +F +EML+KW+A GF+KYFTNAWCWLDF+IV VSL+
Sbjct: 1225 EDIYLEERKTIKVLLEYADKMFTYVFVLEMLLKWVAYGFKKYFTNAWCWLDFLIVDVSLV 1284
Query: 1298 NFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIF 1357
+ VA G + K++RTLRALRPLRA+SR +GMRVVVNALV AIPSI NVLLVCLIF
Sbjct: 1285 SLVANTLGFAEMGPIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIF 1344
Query: 1358 WLIFAIMGVQLFAGKYFKCVDMNH--TTLSHEIIPDKNACTLENYT----WENSPMNFDH 1411
WLIF+IMGV LFAGK+ +C++ L++ I+ +K+ C N T W +NFD+
Sbjct: 1345 WLIFSIMGVNLFAGKFGRCINQTEGDLPLNYTIVNNKSQCESLNLTGELYWTKVKVNFDN 1404
Query: 1412 VGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNL 1471
VG YL L QVATFKGW+ IM A+DSR QP E N+YMY+Y TLNL
Sbjct: 1405 VGAGYLALLQVATFKGWMDIMYAAVDSRGYEEQPQWEYNLYMYIYFVIFIIFGSFFTLNL 1464
Query: 1472 FIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFE 1531
FIGVIIDNFN+QKKK GG ++FMTE+QKKYYNAMKK+GSKKP K IPRP + Q +F+
Sbjct: 1465 FIGVIIDNFNQQKKKLGGQ-DIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKYQGFIFD 1523
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR 1591
IVT + FD+ IM I LNM+TM ++ QS +L +N++F+ IF+ EC++K+ ALR
Sbjct: 1524 IVTKQAFDVTIMFLICLNMVTMMVETDDQSPEKINILAKINLLFVAIFTGECIVKLAALR 1583
Query: 1592 YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGI 1651
++YF WN+FDFVVV+ SI+ VLSDII+KYF SPTL RV+R+A++GR+LRL++GAKGI
Sbjct: 1584 HYYFTNSWNIFDFVVVILSIVGTVLSDIIQKYFFSPTLFRVIRLARIGRILRLIRGAKGI 1643
Query: 1652 RTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMIL 1711
RTLLFAL MSLPALFNI LLLFLVMFI++IFGM+ F +VK + G+DD++NF+TF SM+
Sbjct: 1644 RTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMANFAYVKWEAGIDDMFNFQTFANSMLC 1703
Query: 1712 LFQMSTSAGWDGVLDGIIN--EEECD--LPDNERGSPGNCGSATIGITYLLSYLVISFLI 1767
LFQ++TSAGWDG+L I+N CD LP N GS G+CGS +GI + +Y++ISFLI
Sbjct: 1704 LFQITTSAGWDGLLSPILNTGPPYCDPTLP-NSNGSRGDCGSPAVGILFFTTYIIISFLI 1762
Query: 1768 VINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLE 1827
V+NMYIA+ILEN+S ATE+ E L++DD+DM+YEIW++FDP+ +Q+I Y LSDF D L
Sbjct: 1763 VVNMYIAIILENFSVATEESTEPLSEDDFDMFYEIWEKFDPEATQFIEYSVLSDFADALS 1822
Query: 1828 PPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTKDFFARKGN----PIEETGDLEVG 1883
PL+I KPN+ +I+MD+P+ GD + C+DIL A TK G I+
Sbjct: 1823 EPLRIAKPNQISLINMDLPMVSGDRIHCMDILFAFTKRVLGESGEMDALKIQMEEKFMAA 1882
Query: 1884 RPEEAGYEPVSSTLWRQREEYCARLIQ 1910
P + YEP+++TL R+ EE A +IQ
Sbjct: 1883 NPSKISYEPITTTLRRKHEEVSAMVIQ 1909
Score = 405 bits (996), Expect = e-111
Identities = 214/414 (51%), Positives = 275/414 (66%), Gaps = 28/414 (6%)
Query: 14 SLFRPFTRESLXXXXXXXXXXXXKQKELEKKRAEGEVRYXXXXXXXGPQPDATLEQGLPL 73
S FR FTRESL + ++ EG P+P L+ L
Sbjct: 11 SSFRRFTRESLAAIEKRMAEKQARGSTTLQESREG------LPEEEAPRPQLDLQASKKL 64
Query: 74 PVRMQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNALWILDPFNPIRRV 133
P + G+ P EL PLED+DPFY Q TF+V++KGK IFRFSATNAL++L PF+P+RR
Sbjct: 65 P-DLYGNPPQELIGEPLEDLDPFYSTQKTFIVLNKGKTIFRFSATNALYVLSPFHPVRRA 123
Query: 134 AIYILVHPLFSLFIITTILVNCILMIMPTTPT-VESTEVIFTGIYTFESAVKVMARGFIL 192
A+ ILVH LF++ I+ TIL NC+ M P + E FT IYTFES VK++AR F L
Sbjct: 124 AVKILVHSLFNMLIMCTILTNCVFMAQHDPPPWTKYVEYTFTAIYTFESLVKILARAFCL 183
Query: 193 QPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAV 252
FT+LRD WNWLDF VI +AY T +DLGN++ALRTFRVLRALKT++++ GLKTIVGA+
Sbjct: 184 HAFTFLRDPWNWLDFSVIIMAYTTEFVDLGNVSALRTFRVLRALKTISVISGLKTIVGAL 243
Query: 253 IESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPE-DGSWGNLTDEN--WER 309
I+SVK L DV++LT+F LSVFAL+GLQ++MG L KCV+ F +G+ G++ + WE
Sbjct: 244 IQSVKKLADVMVLTVFCLSVFALIGLQLFMGNLRHKCVRNFTALNGTNGSVEADGLVWES 303
Query: 310 ---FCQNETNWYGEGG--DYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAF 364
+ + N+ + G D LCGNSS AG C GY CL+ G NP++GYTSFD+F WAF
Sbjct: 304 LDLYLSDPENYLLKNGTSDVLLCGNSSDAGTCPEGYRCLKA-GENPDHGYTSFDSFAWAF 362
Query: 365 LSAFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
L+ FRLMTQD WE LYQ +FF+++IFLGSFYLVNLILA+VAM+Y
Sbjct: 363 LALFRLMTQDCWERLYQQTLRSAGKIYMIFFMLVIFLGSFYLVNLILAVVAMAY 416
Score = 103 bits (247), Expect = 5e-20
Identities = 77/256 (30%), Positives = 135/256 (52%), Gaps = 31/256 (12%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL- 1590
+V D D+ I + I LN L M L+HY + F +L N++F IF++E KI AL
Sbjct: 713 VVMDPFTDLTITMCIVLNTLFMALEHYNMTSEFEEMLQVGNLVFTGIFTAEMTFKIIALD 772
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
Y+YF + WN+FD ++V+ S++ L LS + + L V+R ++ RV +L K
Sbjct: 773 PYYYFQQGWNIFDSIIVILSLMELGLSRM--------SNLSVLRSFRLLRVFKLAKSWPT 824
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF----MHVKDK-GGLDDVYNFKTF 1705
+ TL+ + S+ AL N+ L+L +++FIFA+ GM F ++D GL ++ F
Sbjct: 825 LNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKNYSELRDSDSGLLPRWHMMDF 884
Query: 1706 VQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISF 1765
+ +++F+ +L G E D + G + + +LL +VI
Sbjct: 885 FHAFLIIFR---------ILCGEWIETMWDCMEVS-------GQSLCLLVFLL-VMVIGN 927
Query: 1766 LIVINMYIAVILENYS 1781
L+V+N+++A++L ++S
Sbjct: 928 LVVLNLFLALLLSSFS 943
Score = 86.6 bits (205), Expect = 6e-15
Identities = 73/291 (25%), Positives = 142/291 (48%), Gaps = 32/291 (10%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMI-----MPTTPTV----ESTEVIFTGIYTFE 180
+R+ +I+ H F FII IL++ + + T+ E + +FT ++ E
Sbjct: 1194 LRKTCYHIVEHSWFETFIIFMILLSSGALAFEDIYLEERKTIKVLLEYADKMFTYVFVLE 1253
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV-----TMGI-DLGNLAALRTFRVLR 234
+K +A GF Y +AW WLDF+++ ++ V T+G ++G + +LRT R LR
Sbjct: 1254 MLLKWVAYGFK----KYFTNAWCWLDFLIVDVSLVSLVANTLGFAEMGPIKSLRTLRALR 1309
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFP 294
L+ ++ G++ +V A++ ++ ++ +V+++ + +F++MG+ ++ G +C+
Sbjct: 1310 PLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKF-GRCINQTE 1368
Query: 295 EDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGY 354
D N T N + C++ N GE + N G + + F + Y
Sbjct: 1369 GDLPL-NYTIVNNKSQCES-LNLTGELYWTKVKVNFDNVGAGYLALLQVATFKGWMDIMY 1426
Query: 355 TSFDTFGWAFLSAFRLMTQDYWE-NLYQ-LFFVVIIFLGSFYLVNLILAIV 403
+ D+ G+ Q WE NLY ++FV+ I GSF+ +NL + ++
Sbjct: 1427 AAVDSRGYE--------EQPQWEYNLYMYIYFVIFIIFGSFFTLNLFIGVI 1469
Score = 80.6 bits (190), Expect = 4e-13
Identities = 41/105 (39%), Positives = 62/105 (59%), Gaps = 5/105 (4%)
Query: 727 EQAGRQSRASELNVSVYYFPTAEDDEDGPTFKEKLLDCLMKGIDFFCVWDCCWLWLEFQK 786
E+ G + RA VSV E +E + K C + + +W+CC LW+ ++
Sbjct: 654 EEPGARQRALSA-VSVLTSALEELEES----RHKCPPCWNRLAQRYLIWECCPLWMSIKQ 708
Query: 787 YVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGN 831
V L+V DPF +L IT+CIV+NTLFMAL+H+NM + ++ L+ GN
Sbjct: 709 GVKLVVMDPFTDLTITMCIVLNTLFMALEHYNMTSEFEEMLQVGN 753
Score = 77.4 bits (182), Expect = 4e-12
Identities = 48/177 (27%), Positives = 93/177 (52%), Gaps = 13/177 (7%)
Query: 114 RFSATNALWILDP-FNPIRRVAIYILVHPLFSLFIITTILVNCILMIMP----TTPTVES 168
R + +W P + I++ +++ P L I I++N + M + T+ E
Sbjct: 689 RLAQRYLIWECCPLWMSIKQGVKLVVMDPFTDLTITMCIVLNTLFMALEHYNMTSEFEEM 748
Query: 169 TEV---IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID-LGNL 224
+V +FTGI+T E K++A L P+ Y + WN D +++ L+ + +G+ + NL
Sbjct: 749 LQVGNLVFTGIFTAEMTFKIIA----LDPYYYFQQGWNIFDSIIVILSLMELGLSRMSNL 804
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+ LR+FR+LR K P L T++ + SV L ++ ++ + +FA++G+Q++
Sbjct: 805 SVLRSFRLLRVFKLAKSWPTLNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLF 861
Score = 76.6 bits (180), Expect = 7e-12
Identities = 45/137 (32%), Positives = 79/137 (57%), Gaps = 12/137 (8%)
Query: 1254 YMDRIFTVIFFIEMLIKWLALGFQKY-FT---NAWCWLDFIIVMVSLINFVAALCGAGGI 1309
Y++ FT I+ E L+K LA F + FT + W WLDF +++++ + G +
Sbjct: 159 YVEYTFTAIYTFESLVKILARAFCLHAFTFLRDPWNWLDFSVIIMA---YTTEFVDLGNV 215
Query: 1310 QAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
A +T R LRAL+ + +S G++ +V AL+Q++ + +V+++ + +FA++G+QLF
Sbjct: 216 SALRTFRVLRALKTISVIS---GLKTIVGALIQSVKKLADVMVLTVFCLSVFALIGLQLF 272
Query: 1370 AGKY-FKCVDMNHTTLS 1385
G KCV N T L+
Sbjct: 273 MGNLRHKCV-RNFTALN 288
Score = 70.1 bits (164), Expect = 6e-10
Identities = 49/167 (29%), Positives = 82/167 (49%), Gaps = 8/167 (4%)
Query: 1213 KLIENTYFETAVITM-ILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKW 1271
KL+ F ITM I+L++L +ALE ++ +++L + +FT IF EM K
Sbjct: 711 KLVVMDPFTDLTITMCIVLNTLFMALEHYNMTSE--FEEMLQVGNLVFTGIFTAEMTFKI 768
Query: 1272 LALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQ 1331
+AL YF W D IIV++SL+ G + +R+ R LR +
Sbjct: 769 IALDPYYYFQQGWNIFDSIIVILSLMEL-----GLSRMSNLSVLRSFRLLRVFKLAKSWP 823
Query: 1332 GMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD 1378
+ ++ + ++ ++ N+ LV I IFA++G+QLF Y + D
Sbjct: 824 TLNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKNYSELRD 870
Score = 53.6 bits (123), Expect = 5e-05
Identities = 44/163 (26%), Positives = 76/163 (46%), Gaps = 20/163 (12%)
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL 1590
+I+ F+M+IM I N + M H T Y+ F I++ E L+KI A
Sbjct: 126 KILVHSLFNMLIMCTILTNCVFMA-QHDPPPWT-----KYVEYTFTAIYTFESLVKILAR 179
Query: 1591 RY--HYFV---EPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLV 1645
+ H F +PWN DF V++ + + FV + +R +V R L+ +
Sbjct: 180 AFCLHAFTFLRDPWNWLDFSVIIMAYTT---------EFVDLGNVSALRTFRVLRALKTI 230
Query: 1646 KGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
G++T++ AL S+ L ++ +L + +FA+ G+ FM
Sbjct: 231 SVISGLKTIVGALIQSVKKLADVMVLTVFCLSVFALIGLQLFM 273
Score = 43.2 bits (97), Expect = 0.074
Identities = 40/169 (23%), Positives = 82/169 (48%), Gaps = 21/169 (12%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT---TPT----VESTEVIFTGIYT 178
P N + I+ F + I+ I +N + M++ T +P + ++F I+T
Sbjct: 1513 PLNKYQGFIFDIVTKQAFDVTIMFLICLNMVTMMVETDDQSPEKINILAKINLLFVAIFT 1572
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV-TMGIDLGN--------LAALRT 229
E VK+ A L+ + Y ++WN DFVV+ L+ V T+ D+ +R
Sbjct: 1573 GECIVKLAA----LRHY-YFTNSWNIFDFVVVILSIVGTVLSDIIQKYFFSPTLFRVIRL 1627
Query: 230 FRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGL 278
R+ R L+ + G++T++ A++ S+ L ++ +L + ++++ G+
Sbjct: 1628 ARIGRILRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGM 1676
>UniRef50_Q25377 Cluster: Sodium channel; n=1; Loligo opalescens|Rep:
Sodium channel - Loligo opalescens (California market
squid)
Length = 1784
Score = 914 bits (2262), Expect = 0.0
Identities = 443/743 (59%), Positives = 557/743 (74%), Gaps = 11/743 (1%)
Query: 1176 TPADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLAL 1235
TP DC + C + + F + W LR +K++E+ YFET +ITMIL SSLAL
Sbjct: 981 TPDDCLCQFCNRNCNCWGYFQHTDFGKAWWKLRCFMYKVVEHEYFETFIITMILASSLAL 1040
Query: 1236 ALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVS 1295
ALED+HL +PILQ +L YMD+ FTVIF EM IKW A G++KYFT+AWCWLDF+IV VS
Sbjct: 1041 ALEDIHLRKKPILQLVLKYMDKCFTVIFIGEMFIKWFAFGWKKYFTDAWCWLDFLIVAVS 1100
Query: 1296 LINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCL 1355
+I A G G + AF++MRTLRALRPLRA+SR +GMRVVVNAL++A+PSIFNVLLVCL
Sbjct: 1101 IIMLAAESIGMGNLTAFRSMRTLRALRPLRAVSRSEGMRVVVNALIKAVPSIFNVLLVCL 1160
Query: 1356 IFWLIFAIMGVQLFAGKYFKCV-DMNHTTLSHEIIPDKNACTLEN---YTWENSPMNFDH 1411
+FWLIF+IMGVQLF GK+ KCV + N TT+ + +++ C EN Y W+NSP+NFD+
Sbjct: 1161 VFWLIFSIMGVQLFNGKFHKCVYNFNGTTVPATEVNNRSECE-ENPMLYKWKNSPINFDN 1219
Query: 1412 VGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNL 1471
V YL LFQVATFKGWI IM+DA D R++G QPI+E +I MYLY TLNL
Sbjct: 1220 VLNGYLALFQVATFKGWINIMSDATDIRDIGDQPIKENSILMYLYFVLFIIFGSFFTLNL 1279
Query: 1472 FIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFE 1531
FIGVIIDNFN+QKK AGGSLE+FMT+DQKKYY AMK + SKKP K IP P ++ +F
Sbjct: 1280 FIGVIIDNFNQQKKGAGGSLEVFMTDDQKKYYKAMKNLQSKKPTKGIPMPGFKIAEWMFH 1339
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR 1591
+ T++KFD+ IM+ I LNM+TM ++HY S TF L Y+NM+FI IF+ EC++K+ LR
Sbjct: 1340 LTTNQKFDVAIMMVILLNMITMAMEHYNMSRTFEDFLKYINMVFIGIFTGECVMKLMGLR 1399
Query: 1592 YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGI 1651
++YF EPWN+FDFVVV+ SIL + LSDII++YFVSPTLLRVVRV +VGRVLRLVK AKGI
Sbjct: 1400 FYYFKEPWNIFDFVVVVLSILGIALSDIIKQYFVSPTLLRVVRVFRVGRVLRLVKSAKGI 1459
Query: 1652 RTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMIL 1711
RTLLF+LA+SLPALFNI LLLFLVMFI+++FGMSFFM V G+DDV+NF+T +QSMIL
Sbjct: 1460 RTLLFSLAVSLPALFNIGLLLFLVMFIYSMFGMSFFMDVGYFDGIDDVFNFQTLIQSMIL 1519
Query: 1712 LFQMSTSAGWDGVLDGIINEEECDLPD----NERGSPGNCGSATIGITYLLSYLVISFLI 1767
LFQMSTSAGWDGVL I+ E PD + + GNCG+ + + +L++YLVISFL+
Sbjct: 1520 LFQMSTSAGWDGVLAAIMREPPACQPDLKIFGSKSNNGNCGNYGMAVMFLVTYLVISFLV 1579
Query: 1768 VINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLE 1827
VINMYIAVILEN+SQATEDVQ+GLT DD+DMYYE W++FDP +QYI +LSDF+D LE
Sbjct: 1580 VINMYIAVILENFSQATEDVQQGLTPDDFDMYYEKWEKFDPKATQYIALSELSDFVDFLE 1639
Query: 1828 PPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTKDFFARKGNPIEETGDLEVGRPEE 1887
PLQ+ KPN + ++ +DIPIC G+ + CVDIL ALTK++ + E G E+
Sbjct: 1640 EPLQLPKPNHFMLVRLDIPICEGERVHCVDILAALTKNYLGTLDDASAEGG--AQPEAEK 1697
Query: 1888 AGYEPVSSTLWRQREEYCARLIQ 1910
Y P+SSTL RQ+E + AR+IQ
Sbjct: 1698 LDYNPISSTLRRQKEHFAARIIQ 1720
Score = 428 bits (1054), Expect = e-118
Identities = 220/418 (52%), Positives = 277/418 (66%), Gaps = 29/418 (6%)
Query: 2 SEDLDSISEEERSLFRPFTRESLXXXXXXXXXXXXKQKELEKKRAEGEVRYXXXXXXXGP 61
++DL+ + + FR FTRE+L + ++ + E E P
Sbjct: 4 AKDLEK-GDNPKGRFRLFTRETLFEIERRIAERRAQAEDADSDEEENEPELK-------P 55
Query: 62 QPDATLEQGLPLPVRMQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNAL 121
P +GLP V P PLED+D +YHN TF VI + + ++RFSAT A+
Sbjct: 56 NPKFEAGKGLPPSVE---DVPSRYQGRPLEDLDEYYHNNKTFCVIGRDRTLYRFSATKAI 112
Query: 122 WILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFES 181
++L PFNPIRR AI+ILVHP+FSL +I TI+ NC+ M M P S E IFTGIYT E+
Sbjct: 113 FLLSPFNPIRRFAIFILVHPIFSLVVILTIVCNCVFMTMKENPLPVS-EWIFTGIYTCEA 171
Query: 182 AVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAI 241
+K+ ARGFIL+PFTYLRDAWNWLDFVVI LAY+T +DLGNL+ALRTFRVLRALKTVA+
Sbjct: 172 LIKLFARGFILEPFTYLRDAWNWLDFVVIGLAYLTEVVDLGNLSALRTFRVLRALKTVAV 231
Query: 242 VPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGN 301
+PGLKTIVGA++E+V+ LRDV+ILT F LS+FAL+G+Q+Y G L KCV+ E N
Sbjct: 232 IPGLKTIVGALLEAVRRLRDVMILTGFMLSIFALIGMQLYQGALRSKCVRNNDE-----N 286
Query: 302 LTDENWERFCQNETNWYGE-GGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTF 360
+TD ++++ + NW G +CGN+SG G+C Y CL NPN+GYTSFD F
Sbjct: 287 MTDSEYQKYVSIKANWQENFYGSTLVCGNASGPGKCGENYTCLPEIMDNPNFGYTSFDNF 346
Query: 361 GWAFLSAFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
WA L AFRLMTQDYWENLYQ LFF+++IFLGSFYLVNLILAIVAMSY
Sbjct: 347 AWAMLCAFRLMTQDYWENLYQLVIRAEGPVHALFFILVIFLGSFYLVNLILAIVAMSY 404
Score = 197 bits (481), Expect = 2e-48
Identities = 105/225 (46%), Positives = 137/225 (60%), Gaps = 8/225 (3%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+S LRVFKLAKSWPTLN+LISI+ TMGALGNLT VL II+FIFAVMG QLFG NY
Sbjct: 682 LRSFRLLRVFKLAKSWPTLNMLISIVAGTMGALGNLTLVLGIIVFIFAVMGQQLFGANY- 740
Query: 887 DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVSCIPFFLATVVIX 946
+ + F D +PRW F F+HSFMIVFRVLCGEWIESMW CM V +C+PFFL T++I
Sbjct: 741 EKPECFEDNQVPRWGFRTFLHSFMIVFRVLCGEWIESMWTCMEVAGYACVPFFLLTMIIG 800
Query: 947 XXXXXXXXXXXXXXXXXXXXXXTPTADQDTNKIAEAFNRISRFIDWIKRNVADFLKLLKN 1006
+ +D + NK+ EA +RI RF W+K ++ LK K
Sbjct: 801 NLVVLNLFLALLLSSFGAESLQSSKSDDEPNKLQEAIDRIVRFTHWVKMSL---LKCAKY 857
Query: 1007 KLTNQIAIHAPERVDNELELGTDL--DDAVLYKDKKLKDQVEVAI 1049
K + I+ PE ++ G ++ D + + K D+++ A+
Sbjct: 858 KFKKK-PINRPELPKVDIN-GKEIIGDGHAIIGNGKFGDKIDDAV 900
Score = 98.3 bits (234), Expect = 2e-18
Identities = 78/279 (27%), Positives = 138/279 (49%), Gaps = 34/279 (12%)
Query: 1533 VTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR- 1591
+ D D+ I L I LN + M +DHY E L+ N +F +F++E LKI AL
Sbjct: 589 IMDAFVDLFITLCIVLNTVFMAIDHYDMQEGLRVALEIGNYVFTAVFAAEAFLKILALAP 648
Query: 1592 YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGI 1651
YF +PWN+FD +V S++ L L I L V+R ++ RV +L K +
Sbjct: 649 QTYFKDPWNVFDSFIVFLSLMELGLGGI--------QGLSVLRSFRLLRVFKLAKSWPTL 700
Query: 1652 RTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF--MHVKDKGGLDDV---YNFKTFV 1706
L+ +A ++ AL N+ L+L +++FIFA+ G F + K + D+ + F+TF+
Sbjct: 701 NMLISIVAGTMGALGNLTLVLGIIVFIFAVMGQQLFGANYEKPECFEDNQVPRWGFRTFL 760
Query: 1707 QSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFL 1766
S +++F++ W ++ + E G A + + L ++I L
Sbjct: 761 HSFMIVFRV-LCGEW---IESMWTCMEV------------AGYAC--VPFFLLTMIIGNL 802
Query: 1767 IVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQR 1805
+V+N+++A++L ++ E +Q +DD+ + E R
Sbjct: 803 VVLNLFLALLLSSF--GAESLQSSKSDDEPNKLQEAIDR 839
Score = 96.3 bits (229), Expect = 8e-18
Identities = 56/138 (40%), Positives = 82/138 (59%), Gaps = 18/138 (13%)
Query: 697 KPSSDNPFI-ESSQQPNVVDMRDVMVLNEIIEQAGRQSRASELNVSVYYFPTAEDDEDGP 755
K ++NPF+ SS NVVDM+DVMVL ++I+ A +R+S ++ S +
Sbjct: 510 KNYANNPFLCPSSSATNVVDMKDVMVLKDLIDHASG-ARSSSVSSS---------ESQPE 559
Query: 756 TFKEKLLDCLMKGIDFFCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALD 815
KEKL I FC WDC + + Y+ + D FV+LFITLCIV+NT+FMA+D
Sbjct: 560 LLKEKL-------IRIFCAWDCYPPFKTLRGYIGFFIMDAFVDLFITLCIVLNTVFMAID 612
Query: 816 HHNMDKDMDKALKSGNYL 833
H++M + + AL+ GNY+
Sbjct: 613 HYDMQEGLRVALEIGNYV 630
Score = 82.6 bits (195), Expect = 1e-13
Identities = 77/284 (27%), Positives = 137/284 (48%), Gaps = 35/284 (12%)
Query: 137 ILVHPLFSLFIITTILVNCILMIM--------PTTPTV-ESTEVIFTGIYTFESAVKVMA 187
++ H F FIIT IL + + + + P V + + FT I+ E +K A
Sbjct: 1019 VVEHEYFETFIITMILASSLALALEDIHLRKKPILQLVLKYMDKCFTVIFIGEMFIKWFA 1078
Query: 188 RGFILQPFTYLRDAWNWLDFVVIALAYVTM---GIDLGNLAALRTFRVLRALKTVAIV-- 242
G+ Y DAW WLDF+++A++ + + I +GNL A R+ R LRAL+ + V
Sbjct: 1079 FGWK----KYFTDAWCWLDFLIVAVSIIMLAAESIGMGNLTAFRSMRTLRALRPLRAVSR 1134
Query: 243 -PGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGN 301
G++ +V A+I++V ++ +V+++ + +F++MG+Q++ G KCV F +G+
Sbjct: 1135 SEGMRVVVNALIKAVPSIFNVLLVCLVFWLIFSIMGVQLFNGKF-HKCVYNF--NGTTVP 1191
Query: 302 LTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFG 361
T+ N C+ Y + + P+ GY+ L F G+ + +
Sbjct: 1192 ATEVNNRSECEENPMLY-KWKNSPI-----NFDNVLNGYLAL--FQVATFKGWINIMSDA 1243
Query: 362 WAFLSAFRLMTQDYWEN--LYQLFFVVIIFLGSFYLVNLILAIV 403
+ Q EN L L+FV+ I GSF+ +NL + ++
Sbjct: 1244 TDIRD---IGDQPIKENSILMYLYFVLFIIFGSFFTLNLFIGVI 1284
Score = 74.5 bits (175), Expect = 3e-11
Identities = 50/170 (29%), Positives = 84/170 (49%), Gaps = 7/170 (4%)
Query: 1206 TLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFI 1265
TLR I + + + + I+L+++ +A++ H + L+ L + +FT +F
Sbjct: 580 TLRGYIGFFIMDAFVDLFITLCIVLNTVFMAID--HYDMQEGLRVALEIGNYVFTAVFAA 637
Query: 1266 EMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLR 1325
E +K LAL Q YF + W D IV +SL+ G GGIQ +R+ R LR +
Sbjct: 638 EAFLKILALAPQTYFKDPWNVFDSFIVFLSLMEL-----GLGGIQGLSVLRSFRLLRVFK 692
Query: 1326 AMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK 1375
+ ++++ + + ++ N+ LV I IFA+MG QLF Y K
Sbjct: 693 LAKSWPTLNMLISIVAGTMGALGNLTLVLGIIVFIFAVMGQQLFGANYEK 742
Score = 73.7 bits (173), Expect = 5e-11
Identities = 45/133 (33%), Positives = 75/133 (56%), Gaps = 11/133 (8%)
Query: 1258 IFTVIFFIEMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFK 1313
IFT I+ E LIK A GF Y +AW WLDF+++ ++ + V L G + A +
Sbjct: 162 IFTGIYTCEALIKLFARGFILEPFTYLRDAWNWLDFVVIGLAYLTEVVDL---GNLSALR 218
Query: 1314 TMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
T R LRAL+ + + G++ +V AL++A+ + +V+++ IFA++G+QL+ G
Sbjct: 219 TFRVLRALKTVAVIP---GLKTIVGALLEAVRRLRDVMILTGFMLSIFALIGMQLYQGAL 275
Query: 1374 -FKCVDMNHTTLS 1385
KCV N ++
Sbjct: 276 RSKCVRNNDENMT 288
Score = 70.9 bits (166), Expect = 3e-10
Identities = 43/164 (26%), Positives = 82/164 (50%), Gaps = 12/164 (7%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEV-------IFTGIYT 178
PF +R + ++ LFI I++N + M + E V +FT ++
Sbjct: 577 PFKTLRGYIGFFIMDAFVDLFITLCIVLNTVFMAIDHYDMQEGLRVALEIGNYVFTAVFA 636
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID-LGNLAALRTFRVLRALK 237
E+ +K++A L P TY +D WN D ++ L+ + +G+ + L+ LR+FR+LR K
Sbjct: 637 AEAFLKILA----LAPQTYFKDPWNVFDSFIVFLSLMELGLGGIQGLSVLRSFRLLRVFK 692
Query: 238 TVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
P L ++ V ++ L ++ ++ + +FA+MG Q++
Sbjct: 693 LAKSWPTLNMLISIVAGTMGALGNLTLVLGIIVFIFAVMGQQLF 736
Score = 56.8 bits (131), Expect = 6e-06
Identities = 45/167 (26%), Positives = 82/167 (49%), Gaps = 25/167 (14%)
Query: 136 YILVHPLFSLFIITTILVNCILMIMP---TTPTVES----TEVIFTGIYTFESAVKVMAR 188
++ + F + I+ IL+N I M M + T E ++F GI+T E +K+M
Sbjct: 1339 HLTTNQKFDVAIMMVILLNMITMAMEHYNMSRTFEDFLKYINMVFIGIFTGECVMKLMGL 1398
Query: 189 GFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN-----------LAALRTFRVLRALK 237
F Y ++ WN DFVV+ L+ +GI L + L +R FRV R L+
Sbjct: 1399 RFY-----YFKEPWNIFDFVVVVLS--ILGIALSDIIKQYFVSPTLLRVVRVFRVGRVLR 1451
Query: 238 TVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
V G++T++ ++ S+ L ++ +L + ++++ G+ +M V
Sbjct: 1452 LVKSAKGIRTLLFSLAVSLPALFNIGLLLFLVMFIYSMFGMSFFMDV 1498
Score = 48.4 bits (110), Expect = 0.002
Identities = 42/155 (27%), Positives = 75/155 (48%), Gaps = 22/155 (14%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY----- 1592
F ++++L I N + MT+ L IF I++ E L+K+FA +
Sbjct: 134 FSLVVILTIVCNCVFMTMKENP--------LPVSEWIFTGIYTCEALIKLFARGFILEPF 185
Query: 1593 HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIR 1652
Y + WN DFVV+ + L+ V+ D+ L +R +V R L+ V G++
Sbjct: 186 TYLRDAWNWLDFVVIGLAYLTEVV-DLGN--------LSALRTFRVLRALKTVAVIPGLK 236
Query: 1653 TLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
T++ AL ++ L ++ +L ++ IFA+ GM +
Sbjct: 237 TIVGALLEAVRRLRDVMILTGFMLSIFALIGMQLY 271
Score = 37.1 bits (82), Expect = 4.9
Identities = 23/82 (28%), Positives = 44/82 (53%), Gaps = 6/82 (7%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
RV +L KS + L+ + ++ AL N+ +L +++FI+++ GM F V Y D
Sbjct: 1448 RVLRLVKSAKGIRTLLFSLAVSLPALFNIGLLLFLVMFIYSMFGMSFFMD--VGYFDGID 1505
Query: 894 DGDLPRWNFTDFMHSFMIVFRV 915
D +NF + S +++F++
Sbjct: 1506 D----VFNFQTLIQSMILLFQM 1523
>UniRef50_P90670 Cluster: Sodium channel alpha-subunit SCAP1; n=15;
Coelomata|Rep: Sodium channel alpha-subunit SCAP1 -
Aplysia californica (California sea hare)
Length = 1993
Score = 873 bits (2161), Expect = 0.0
Identities = 428/756 (56%), Positives = 544/756 (71%), Gaps = 20/756 (2%)
Query: 1161 KTDIKVGADEDVVDDTPADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYF 1220
+ D ++ E V P DC C ++ P+ + S + W +R ++L EN YF
Sbjct: 1121 EADHEINEVEIVYVKEPDDCFCYMCTKRCPWCVKVEKSKIGRAWWAVRCFFYRLTENKYF 1180
Query: 1221 ETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYF 1280
++ +I MIL SS ALALED +L +PIL++IL Y+D++FT IF IEMLIKWLA GF+ YF
Sbjct: 1181 DSFIIAMILASSCALALEDAYLHEKPILKEILEYLDKVFTAIFIIEMLIKWLAFGFKTYF 1240
Query: 1281 TNAWCWLDFIIVMVSLINFVAALC----GAGGIQAFKTMRTLRALRPLRAMSRMQGMRVV 1336
T+AWCWLDF IVM+S++ VA L G G + K+MRTLRALRPLRA+SR +GMRVV
Sbjct: 1241 TDAWCWLDFTIVMLSIVMLVADLTASEEGGGSMSWMKSMRTLRALRPLRAVSRWEGMRVV 1300
Query: 1337 VNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACT 1396
VNAL +AIPSI NVLLVCL+FWLIF IMGVQLF GK+ C D E +P+K C
Sbjct: 1301 VNALFKAIPSICNVLLVCLVFWLIFGIMGVQLFNGKFHACRDEKGDKYPREEVPNKTVCI 1360
Query: 1397 LENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLY 1456
+ Y W N+ +NFDHV AYL LFQVAT+KGWI IMN+AIDS E+G+QP RE N+ MYL+
Sbjct: 1361 DKGYNWTNAQINFDHVLSAYLALFQVATYKGWIDIMNNAIDSTEIGQQPSREENVIMYLF 1420
Query: 1457 XXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLK 1516
TLNLFIGVII+NFN QKKKAGGSLEMFMTEDQKKYYNAMK+M SK P K
Sbjct: 1421 FVLFIVFCSFFTLNLFIGVIIENFNSQKKKAGGSLEMFMTEDQKKYYNAMKRMQSKSPQK 1480
Query: 1517 AIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFI 1576
+IPRP+++ ++F+I TD+KFD+ IM+ I LNMLTM +H+ S +L N+IFI
Sbjct: 1481 SIPRPKYKLAGLIFDITTDQKFDIAIMVIIILNMLTMMFEHHGMSAQMKNILGIFNLIFI 1540
Query: 1577 VIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVA 1636
IF++EC+LK+ LR++YF PWN+FDFVVV+ SIL+ LS+ + +F+SPTLLRV+RV
Sbjct: 1541 TIFTAECVLKLIGLRWYYFKIPWNVFDFVVVVLSILASSLSEFEDSFFISPTLLRVIRVF 1600
Query: 1637 KVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGL 1696
+VGRVLRLVK AKGIRTLLF++A+SLPALFNI LLL L+MFI+AI GM+FFM + K GL
Sbjct: 1601 RVGRVLRLVKSAKGIRTLLFSMAVSLPALFNIGLLLGLIMFIYAIMGMNFFMGAEQKYGL 1660
Query: 1697 DDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITY 1756
DD +NF TF++S ILLFQM TSAGW VL+G+I C P+ G C + Y
Sbjct: 1661 DDAFNFDTFLRSFILLFQMCTSAGWSDVLNGLI--ARC-APE------GTCKDYNVATIY 1711
Query: 1757 LLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRY 1816
L +YLV+SFL+V+NMYIAVILEN+SQATED Q+GLT DD+DMYYE W+++DP S+YI
Sbjct: 1712 LATYLVVSFLVVVNMYIAVILENFSQATEDEQQGLTPDDFDMYYEKWEKYDPKASKYIPL 1771
Query: 1817 DQLSDFLDVLEPPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTKDFFARKGNPIEE 1876
DQLSDF+D LE PL++ KPN + ++ +DIPIC D +C DILDALTK+F E
Sbjct: 1772 DQLSDFVDYLEEPLRLPKPNHFILVKLDIPICENDRCYCRDILDALTKNFLG-----TGE 1826
Query: 1877 TGDL--EVGRPEEAGYEPVSSTLWRQREEYCARLIQ 1910
T D+ + E+ Y+P+SSTL RQ+E Y AR+IQ
Sbjct: 1827 TSDIPQKETDKEKEEYKPISSTLRRQKEHYAARIIQ 1862
Score = 419 bits (1033), Expect = e-115
Identities = 220/417 (52%), Positives = 281/417 (67%), Gaps = 29/417 (6%)
Query: 16 FRPFTRESLXXXXXXXXXXXXKQKELEKKRAEG----EVRYXXXXXXXGPQPDATLEQGL 71
FR FTRESL K EK E E +P+ LE G
Sbjct: 11 FRLFTRESLFTIDRRIAEEEAA-KHAEKAPPESDDDDEELDEPSHHEENLKPNPKLEAGR 69
Query: 72 PLPVRMQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNALWILDPFNPIR 131
LP ++ +P E PLED+D FYHNQ TFVV+ K K IFRFSAT+A+++L PFNPIR
Sbjct: 70 KLPPSLE-DYPREYVGKPLEDLDEFYHNQKTFVVLKKDKAIFRFSATDAIFLLSPFNPIR 128
Query: 132 RVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMARGFI 191
R+AIYILVHP+FSL ++ TILVNC+ M + + E IF GIYT E+ VKV++RGF+
Sbjct: 129 RIAIYILVHPIFSLLVMMTILVNCVFMAITSYTPPAFVEHIFLGIYTVEAVVKVLSRGFV 188
Query: 192 LQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGNLAALRTFRVLRALKTVAIVPGLKTIVG 250
L+PFTYLRD WNWLDF VI++AY+TM + GNL ALRTFRVLRALKT++++PGLKTIVG
Sbjct: 189 LKPFTYLRDPWNWLDFFVISIAYMTMTVKSFGNLQALRTFRVLRALKTISVIPGLKTIVG 248
Query: 251 AVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCV-KVFPEDGSWGNLTDENWER 309
A++E+V+ LRDV+ILT+F LS+FAL+G+Q+Y G L QKCV PE G+ N+T + W
Sbjct: 249 ALLEAVRRLRDVMILTVFVLSIFALIGMQLYSGALRQKCVLNPVPELGT--NITHDEWND 306
Query: 310 FCQNETNWYGEGGD-YPLCGNSSGAGQCEPG-------YVCLQGFGPNPNYGYTSFDTFG 361
+ NE++W + D + +CGN +GAG+C G ++CL G NPN+ +TSFD FG
Sbjct: 307 WVNNESHWQKDFYDEWQVCGNGTGAGKCGNGTINGTAEWLCLPNIGQNPNHDFTSFDNFG 366
Query: 362 WAFLSAFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
A L AFRLMTQD+WE+LY L+FV++I LGSFYLVNLILAIVAMSY
Sbjct: 367 MALLCAFRLMTQDFWESLYHLVLRAVGSAHCLYFVLVILLGSFYLVNLILAIVAMSY 423
Score = 188 bits (458), Expect = 1e-45
Identities = 95/192 (49%), Positives = 119/192 (61%), Gaps = 8/192 (4%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L++ LRVFKLAKSWPTLN+LI+I+GRTMGALGNL VL IIIFIFAVMG QLF +Y
Sbjct: 844 LRAFRLLRVFKLAKSWPTLNMLIAIVGRTMGALGNLIIVLGIIIFIFAVMGQQLFSSDYK 903
Query: 887 DY---VDRFPD-----GDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVSCIPF 938
Y +D + + +PRWNF DF+HSFMIVFRVLCGEWIESMW C LV +C+PF
Sbjct: 904 TYEREIDAWGNVTINKDKMPRWNFNDFLHSFMIVFRVLCGEWIESMWGCYLVSGWACVPF 963
Query: 939 FLATVVIXXXXXXXXXXXXXXXXXXXXXXXTPTADQDTNKIAEAFNRISRFIDWIKRNVA 998
FL T V+ +D + +KIAEA +R RF +W+K +
Sbjct: 964 FLLTYVVGNLVVLNLFLALLLSSFGSESLQRSESDDEPSKIAEAIDRFKRFGNWVKVKII 1023
Query: 999 DFLKLLKNKLTN 1010
+K+ + N
Sbjct: 1024 VCIKVKLQRQKN 1035
Score = 105 bits (253), Expect = 9e-21
Identities = 103/335 (30%), Positives = 147/335 (43%), Gaps = 52/335 (15%)
Query: 514 TATDTHDSARRPRKVSMASLSLPGSPFNLRRGSRGSHQMALXXXXXXXXXXXXXXXXLVL 573
+AT H R + SLSLPGSP+ RR SRGS Q + L
Sbjct: 491 SATSAHLKPSRLNQ-KRHSLSLPGSPYIHRRNSRGS-QYSWRKPVPTAKRSPYCPDRQPL 548
Query: 574 STYLDAQEHLPYADDSNAVTPMSEE-----------NGAIII------PVYYANLGSRHS 616
+ LP+ADDS AVTP SE+ NG P GSR S
Sbjct: 549 VHHTLENLPLPFADDSAAVTPSSEDLCNFSFIRNMPNGRRFSFASQRRPDGTGRSGSRRS 608
Query: 617 SYTSHQSRLSYTSHGDLLGGGKAQTKEARLRGRSASRNHSVTSQPHAYPLPRQDSSLASR 676
S+ S+ SR S TS G G +TK L + V L S++S
Sbjct: 609 SFASNHSRASRTSRGS---GQGDRTKTQTLLNFKKGKVPDVVLDKSK--LDDDQDSVSSG 663
Query: 677 PLREYEVSTTECTDEAGKVLKPSSDNPFIESSQQPNVVDMRDVMVLNEIIEQAGRQSRAS 736
+ C ++ K S NPF+ S V+M+DVMVL +I++QA R+
Sbjct: 664 -------GSGHCPEKD----KASESNPFLSHSPGGPNVEMKDVMVLKDILDQASGHRRSF 712
Query: 737 ELNVSVYYFPTAEDDEDGPTFKEKLLDCLMKGIDFFCVWDCCWLWLEFQKYVALLVFDPF 796
S++ + + D + K +FC WDC + + Q+ V+L + D F
Sbjct: 713 VSMTSIH--------------QRTMKDIMWK---YFCTWDCHPNFQKLQRLVSLFIMDAF 755
Query: 797 VELFITLCIVVNTLFMALDHHNMDKDMDKALKSGN 831
V+LFIT+CI+VNT FMA++H++M+ D+ + N
Sbjct: 756 VDLFITICILVNTAFMAMEHYDMEDDLKAVSNAAN 790
Score = 91.1 bits (216), Expect = 3e-16
Identities = 79/301 (26%), Positives = 146/301 (48%), Gaps = 43/301 (14%)
Query: 1526 QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLL 1585
Q +V + D D+ I + I +N M ++HY + AV + N++F IF+ E L
Sbjct: 744 QRLVSLFIMDAFVDLFITICILVNTAFMAMEHYDMEDDLKAVSNAANLVFTAIFAVEAFL 803
Query: 1586 KIFALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRL 1644
KI AL YF + WN+FD ++V S++ L ++ + P L V+R ++ RV +L
Sbjct: 804 KILALSPVIYFKDGWNIFDSIIVALSLMELSMTKL-------PG-LSVLRAFRLLRVFKL 855
Query: 1645 VKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF-----MHVKDKGGLDDV 1699
K + L+ + ++ AL N+ ++L +++FIFA+ G F + ++ +V
Sbjct: 856 AKSWPTLNMLIAIVGRTMGALGNLIIVLGIIIFIFAVMGQQLFSSDYKTYEREIDAWGNV 915
Query: 1700 ---------YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSA 1750
+NF F+ S +++F++ W + G C L G A
Sbjct: 916 TINKDKMPRWNFNDFLHSFMIVFRV-LCGEWIESMWG------CYLVS---------GWA 959
Query: 1751 TIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDG 1810
+ +LL+Y V+ L+V+N+++A++L ++ +E +Q +DD+ E RF G
Sbjct: 960 CVPF-FLLTY-VVGNLVVLNLFLALLLSSF--GSESLQRSESDDEPSKIAEAIDRFKRFG 1015
Query: 1811 S 1811
+
Sbjct: 1016 N 1016
Score = 77.8 bits (183), Expect = 3e-12
Identities = 54/191 (28%), Positives = 92/191 (48%), Gaps = 17/191 (8%)
Query: 122 WILDP-FNPIRRVAIYILVHPLFSLFIITTILVNCILMIMP-------TTPTVESTEVIF 173
W P F ++R+ ++ LFI ILVN M M + ++F
Sbjct: 734 WDCHPNFQKLQRLVSLFIMDAFVDLFITICILVNTAFMAMEHYDMEDDLKAVSNAANLVF 793
Query: 174 TGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID-LGNLAALRTFRV 232
T I+ E+ +K++A L P Y +D WN D +++AL+ + + + L L+ LR FR+
Sbjct: 794 TAIFAVEAFLKILA----LSPVIYFKDGWNIFDSIIVALSLMELSMTKLPGLSVLRAFRL 849
Query: 233 LRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKV 292
LR K P L ++ V ++ L ++II+ + +FA+MG Q++ K +
Sbjct: 850 LRVFKLAKSWPTLNMLIAIVGRTMGALGNLIIVLGIIIFIFAVMGQQLFSS--DYKTYE- 906
Query: 293 FPEDGSWGNLT 303
E +WGN+T
Sbjct: 907 -REIDAWGNVT 916
Score = 74.5 bits (175), Expect = 3e-11
Identities = 40/129 (31%), Positives = 76/129 (58%), Gaps = 10/129 (7%)
Query: 1254 YMDRIFTVIFFIEMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGI 1309
+++ IF I+ +E ++K L+ GF Y + W WLDF ++ ++ + G +
Sbjct: 165 FVEHIFLGIYTVEAVVKVLSRGFVLKPFTYLRDPWNWLDFFVISIAYMTMTVK--SFGNL 222
Query: 1310 QAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
QA +T R LRAL+ + S + G++ +V AL++A+ + +V+++ + IFA++G+QL+
Sbjct: 223 QALRTFRVLRALKTI---SVIPGLKTIVGALLEAVRRLRDVMILTVFVLSIFALIGMQLY 279
Query: 1370 AGKY-FKCV 1377
+G KCV
Sbjct: 280 SGALRQKCV 288
Score = 72.9 bits (171), Expect = 8e-11
Identities = 39/128 (30%), Positives = 75/128 (58%), Gaps = 14/128 (10%)
Query: 166 VESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDL---- 221
+E + +FT I+ E +K +A GF TY DAW WLDF ++ L+ V + DL
Sbjct: 1212 LEYLDKVFTAIFIIEMLIKWLAFGFK----TYFTDAWCWLDFTIVMLSIVMLVADLTASE 1267
Query: 222 ---GNLA---ALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFAL 275
G+++ ++RT R LR L+ V+ G++ +V A+ +++ ++ +V+++ + +F +
Sbjct: 1268 EGGGSMSWMKSMRTLRALRPLRAVSRWEGMRVVVNALFKAIPSICNVLLVCLVFWLIFGI 1327
Query: 276 MGLQIYMG 283
MG+Q++ G
Sbjct: 1328 MGVQLFNG 1335
Score = 62.1 bits (144), Expect = 1e-07
Identities = 43/159 (27%), Positives = 78/159 (49%), Gaps = 7/159 (4%)
Query: 1215 IENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLAL 1274
I + + + + IL+++ +A+E H L+ + + +FT IF +E +K LAL
Sbjct: 751 IMDAFVDLFITICILVNTAFMAME--HYDMEDDLKAVSNAANLVFTAIFAVEAFLKILAL 808
Query: 1275 GFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMR 1334
YF + W D IIV +SL+ ++ G+ + R LR + ++ + +
Sbjct: 809 SPVIYFKDGWNIFDSIIVALSLMEL--SMTKLPGLSVLRAFRLLRVFKLAKSWPTLNMLI 866
Query: 1335 VVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
+V + A+ N+++V I IFA+MG QLF+ Y
Sbjct: 867 AIVGRTMGALG---NLIIVLGIIIFIFAVMGQQLFSSDY 902
Score = 57.2 bits (132), Expect = 4e-06
Identities = 44/165 (26%), Positives = 85/165 (51%), Gaps = 20/165 (12%)
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKI 1587
I I+ F +++M+ I +N + M + Y T A +++ IF+ I++ E ++K+
Sbjct: 130 IAIYILVHPIFSLLVMMTILVNCVFMAITSY----TPPAFVEH---IFLGIYTVEAVVKV 182
Query: 1588 ----FALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVL 1642
F L+ + Y +PWN DF V+ + +++ + K F + LR RV R L
Sbjct: 183 LSRGFVLKPFTYLRDPWNWLDFFVISIAYMTMTV-----KSFGNLQALRTFRVL---RAL 234
Query: 1643 RLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+ + G++T++ AL ++ L ++ +L V+ IFA+ GM +
Sbjct: 235 KTISVIPGLKTIVGALLEAVRRLRDVMILTVFVLSIFALIGMQLY 279
Score = 48.0 bits (109), Expect = 0.003
Identities = 32/122 (26%), Positives = 61/122 (50%), Gaps = 14/122 (11%)
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN------- 223
+IF I+T E +K++ + Y + WN DFVV+ L+ + +
Sbjct: 1537 LIFITIFTAECVLKLIGLRWY-----YFKIPWNVFDFVVVVLSILASSLSEFEDSFFISP 1591
Query: 224 --LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
L +R FRV R L+ V G++T++ ++ S+ L ++ +L + ++A+MG+ +
Sbjct: 1592 TLLRVIRVFRVGRVLRLVKSAKGIRTLLFSMAVSLPALFNIGLLLGLIMFIYAIMGMNFF 1651
Query: 282 MG 283
MG
Sbjct: 1652 MG 1653
Score = 46.0 bits (104), Expect = 0.011
Identities = 40/163 (24%), Positives = 78/163 (47%), Gaps = 11/163 (6%)
Query: 776 DCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRV 835
+C + + Y + ++ F + + L I+ ++L D + + + ++ RV
Sbjct: 1546 ECVLKLIGLRWYYFKIPWNVFDFVVVVLSILASSLSEFEDSFFISPTLLRVIRVFRVGRV 1605
Query: 836 FKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDG 895
+L KS + L+ M ++ AL N+ +L +I+FI+A+MGM F Y G
Sbjct: 1606 LRLVKSAKGIRTLLFSMAVSLPALFNIGLLLGLIMFIYAIMGMNFFMGAEQKY------G 1659
Query: 896 DLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVS-CIP 937
+NF F+ SF+++F+ +C + W +L G ++ C P
Sbjct: 1660 LDDAFNFDTFLRSFILLFQ-MC---TSAGWSDVLNGLIARCAP 1698
Score = 36.3 bits (80), Expect = 8.5
Identities = 18/78 (23%), Positives = 43/78 (55%), Gaps = 4/78 (5%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF-GK 883
K++++ LR + W + ++++ + + + ++ N+ V + IF +MG+QLF GK
Sbjct: 1277 KSMRTLRALRPLRAVSRWEGMRVVVNALFKAIPSICNVLLVCLVFWLIFGIMGVQLFNGK 1336
Query: 884 NYV---DYVDRFPDGDLP 898
+ + D++P ++P
Sbjct: 1337 FHACRDEKGDKYPREEVP 1354
>UniRef50_P35499 Cluster: Sodium channel protein type 4 subunit alpha;
n=108; Coelomata|Rep: Sodium channel protein type 4
subunit alpha - Homo sapiens (Human)
Length = 1836
Score = 842 bits (2084), Expect = 0.0
Identities = 411/757 (54%), Positives = 556/757 (73%), Gaps = 16/757 (2%)
Query: 1168 ADEDVVDDTPADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITM 1227
A+E+ + P +C E C Q++P L D + W TLR FK++E+ +FET ++ M
Sbjct: 981 AEENPEGEQPEECFTEACVQRWPCLYVDISQGRGKKWWTLRRACFKIVEHNWFETFIVFM 1040
Query: 1228 ILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWL 1287
ILLSS ALA ED+++ R +++ IL Y D++FT IF +EML+KW+A GF+ YFTNAWCWL
Sbjct: 1041 ILLSSGALAFEDIYIEQRRVIRTILEYADKVFTYIFIMEMLLKWVAYGFKVYFTNAWCWL 1100
Query: 1288 DFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSI 1347
DF+IV VS+I+ VA G + K++RTLRALRPLRA+SR +GMRVVVNAL+ AIPSI
Sbjct: 1101 DFLIVDVSIISLVANWLGYSELGPIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSI 1160
Query: 1348 FNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEI--IPDKNACTLENYT---- 1401
NVLLVCLIFWLIF+IMGV LFAGK++ C++ T+ +I + +K+ C +T
Sbjct: 1161 MNVLLVCLIFWLIFSIMGVNLFAGKFYYCINTT-TSERFDISEVNNKSECESLMHTGQVR 1219
Query: 1402 WENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXX 1461
W N +N+D+VG YL L QVATFKGW+ IM A+DSRE QP E N+YMYLY
Sbjct: 1220 WLNVKVNYDNVGLGYLSLLQVATFKGWMDIMYAAVDSREKEEQPQYEVNLYMYLYFVIFI 1279
Query: 1462 XXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRP 1521
TLNLFIGVIIDNFN+QKKK GG ++FMTE+QKKYYNAMKK+GSKKP K IPRP
Sbjct: 1280 IFGSFFTLNLFIGVIIDNFNQQKKKLGGK-DIFMTEEQKKYYNAMKKLGSKKPQKPIPRP 1338
Query: 1522 RWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSS 1581
+ + Q +V+++VT + FD+ IM+ I LNM+TM ++ QS+ +L +NMIFI+IF+
Sbjct: 1339 QNKIQGMVYDLVTKQAFDITIMILICLNMVTMMVETDDQSQLKVDILYNINMIFIIIFTG 1398
Query: 1582 ECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRV 1641
EC+LK+ ALR +YF WN+FDFVVV+ SI+ L LSD+I+KYFVSPTL RV+R+A++GRV
Sbjct: 1399 ECVLKMLALRQYYFTVGWNIFDFVVVILSIVGLALSDLIQKYFVSPTLFRVIRLARIGRV 1458
Query: 1642 LRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYN 1701
LRL++GAKGIRTLLFAL MSLPALFNI LLLFLVMFI++IFGMS F +VK + G+DD++N
Sbjct: 1459 LRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMSNFAYVKKESGIDDMFN 1518
Query: 1702 FKTFVQSMILLFQMSTSAGWDGVLDGIINE--EECD--LPDNERGSPGNCGSATIGITYL 1757
F+TF S+I LF+++TSAGWDG+L+ I+N +CD L + G+CG+ +IGI +
Sbjct: 1519 FETFGNSIICLFEITTSAGWDGLLNPILNSGPPDCDPNLENPGTSVKGDCGNPSIGICFF 1578
Query: 1758 LSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYD 1817
SY++ISFLIV+NMYIA+ILEN++ ATE+ E L +DD++M+YE W++FDPD +Q+I Y
Sbjct: 1579 CSYIIISFLIVVNMYIAIILENFNVATEESSEPLGEDDFEMFYETWEKFDPDATQFIAYS 1638
Query: 1818 QLSDFLDVLEPPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTKDFFARKG--NPIE 1875
+LSDF+D L+ PL+I KPNK K+I++D+P+ GD + C+DIL ALTK+ G + ++
Sbjct: 1639 RLSDFVDTLQEPLRIAKPNKIKLITLDLPMVPGDKIHCLDILFALTKEVLGDSGEMDALK 1698
Query: 1876 ETGD--LEVGRPEEAGYEPVSSTLWRQREEYCARLIQ 1910
+T + P + YEP+++TL R+ EE CA IQ
Sbjct: 1699 QTMEEKFMAANPSKVSYEPITTTLKRKHEEVCAIKIQ 1735
Score = 300 bits (736), Expect = 3e-79
Identities = 156/304 (51%), Positives = 209/304 (68%), Gaps = 14/304 (4%)
Query: 17 RPFTRESLXXXXXXXXXXXXKQKELEKKRAEGEVRYXXXXXXXGPQPDATLEQGLPLPVR 76
RPFTRESL + + ++ E R +P + LE G LP+
Sbjct: 18 RPFTRESLAAIEQRAVEEEARLQRNKQMEIEEPER----------KPRSDLEAGKNLPM- 66
Query: 77 MQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNALWILDPFNPIRRVAIY 136
+ G P E+ PLED+DP+Y N+ TF+V++KGK IFRFSAT AL++L PF+ +RR AI
Sbjct: 67 IYGDPPPEVIGIPLEDLDPYYSNKKTFIVLNKGKAIFRFSATPALYLLSPFSVVRRGAIK 126
Query: 137 ILVHPLFSLFIITTILVNCILMIMPTTPT-VESTEVIFTGIYTFESAVKVMARGFILQPF 195
+L+H LFS+FI+ TIL NC+ M M P ++ E FTGIYTFES +K++ARGF + F
Sbjct: 127 VLIHALFSMFIMITILTNCVFMTMSDPPPWSKNVEYTFTGIYTFESLIKILARGFCVDDF 186
Query: 196 TYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIES 255
T+LRD WNWLDF VI +AY+T +DLGN++ALRTFRVLRALKT+ ++PGLKTIVGA+I+S
Sbjct: 187 TFLRDPWNWLDFSVIMMAYLTEFVDLGNISALRTFRVLRALKTITVIPGLKTIVGALIQS 246
Query: 256 VKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNET 315
VK L DV+ILT+F LSVFAL+GLQ++MG L QKCV+ +P + N T + + + N+T
Sbjct: 247 VKKLSDVMILTVFCLSVFALVGLQLFMGNLRQKCVR-WPPPFNDTNTTWYSNDTWYGNDT 305
Query: 316 NWYG 319
WYG
Sbjct: 306 -WYG 308
Score = 169 bits (411), Expect = 7e-40
Identities = 89/184 (48%), Positives = 111/184 (60%), Gaps = 5/184 (2%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+S LRVFKLAKSWPTLN+LI I+G ++GALGNLT VL II+FIFAV+GMQLFGK+Y
Sbjct: 668 LRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYK 727
Query: 887 DYVDRFP-DGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCM-LVGDVSCIPFFLATVV 944
+ V + D +LPRW+ DF HSF+IVFR+LCGEWIE+MWDCM + G C+ FL +V
Sbjct: 728 ECVCKIALDCNLPRWHMHDFFHSFLIVFRILCGEWIETMWDCMEVAGQAMCLTVFLMVMV 787
Query: 945 IXXXXXXXXXXXXXXXXXXXXXXXTPTADQDTNKIAEAFNRISRFIDWIKRNVADFLKLL 1004
I D + N + A RI I + K A L LL
Sbjct: 788 IGNLVVLNLFLALLLSSFSADSLAASDEDGEMNNLQIAIGRIKLGIGFAK---AFLLGLL 844
Query: 1005 KNKL 1008
K+
Sbjct: 845 HGKI 848
Score = 143 bits (347), Expect = 4e-32
Identities = 73/123 (59%), Positives = 86/123 (69%), Gaps = 14/123 (11%)
Query: 298 SWGNLTDENWERFCQNETNWYG-EGG-DYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYT 355
SW +W+ + +E N+Y EG D LCGNSS AG C GY C++ G NPNYGYT
Sbjct: 329 SWATNDTFDWDAYISDEGNFYFLEGSNDALLCGNSSDAGHCPEGYECIKT-GRNPNYGYT 387
Query: 356 SFDTFGWAFLSAFRLMTQDYWENLYQL-----------FFVVIIFLGSFYLVNLILAIVA 404
S+DTF WAFL+ FRLMTQDYWENL+QL FFVVIIFLGSFYL+NLILA+VA
Sbjct: 388 SYDTFSWAFLALFRLMTQDYWENLFQLTLRAAGKTYMIFFVVIIFLGSFYLINLILAVVA 447
Query: 405 MSY 407
M+Y
Sbjct: 448 MAY 450
Score = 98.7 bits (235), Expect = 1e-18
Identities = 79/262 (30%), Positives = 135/262 (51%), Gaps = 33/262 (12%)
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKI 1587
I+ IV D D+ I + I LN L M ++HY +E F VL N++F IF++E +LK+
Sbjct: 570 IIHLIVMDPFVDLGITICIVLNTLFMAMEHYPMTEHFDNVLTVGNLVFTGIFTAEMVLKL 629
Query: 1588 FAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVK 1646
A+ Y YF + WN+FD ++V S++ L L+++ L V+R ++ RV +L K
Sbjct: 630 IAMDPYEYFQQGWNIFDSIIVTLSLVELGLANV--------QGLSVLRSFRLLRVFKLAK 681
Query: 1647 GAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF-MHVKD---KGGLD---DV 1699
+ L+ + S+ AL N+ L+L +++FIFA+ GM F K+ K LD
Sbjct: 682 SWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKIALDCNLPR 741
Query: 1700 YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLS 1759
++ F S +++F++ W I +C E C +T L
Sbjct: 742 WHMHDFFHSFLIVFRI-LCGEW------IETMWDC----MEVAGQAMC------LTVFLM 784
Query: 1760 YLVISFLIVINMYIAVILENYS 1781
+VI L+V+N+++A++L ++S
Sbjct: 785 VMVIGNLVVLNLFLALLLSSFS 806
Score = 81.4 bits (192), Expect = 2e-13
Identities = 45/164 (27%), Positives = 85/164 (51%), Gaps = 7/164 (4%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
++ + + + + I+L++L +A+E H P ++L + +FT IF EM++K +A
Sbjct: 574 IVMDPFVDLGITICIVLNTLFMAME--HYPMTEHFDNVLTVGNLVFTGIFTAEMVLKLIA 631
Query: 1274 LGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGM 1333
+ +YF W D IIV +SL+ G +Q +R+ R LR + +
Sbjct: 632 MDPYEYFQQGWNIFDSIIVTLSLVEL-----GLANVQGLSVLRSFRLLRVFKLAKSWPTL 686
Query: 1334 RVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCV 1377
+++ + ++ ++ N+ LV I IFA++G+QLF Y +CV
Sbjct: 687 NMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECV 730
Score = 79.8 bits (188), Expect = 7e-13
Identities = 47/173 (27%), Positives = 92/173 (53%), Gaps = 13/173 (7%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTE-------VIFTGIYT 178
P+ + + I++ P L I I++N + M M P E + ++FTGI+T
Sbjct: 563 PWLKFKNIIHLIVMDPFVDLGITICIVLNTLFMAMEHYPMTEHFDNVLTVGNLVFTGIFT 622
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGNLAALRTFRVLRALK 237
E +K++A + P+ Y + WN D +++ L+ V +G+ ++ L+ LR+FR+LR K
Sbjct: 623 AEMVLKLIA----MDPYEYFQQGWNIFDSIIVTLSLVELGLANVQGLSVLRSFRLLRVFK 678
Query: 238 TVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCV 290
P L ++ + SV L ++ ++ + +FA++G+Q++ G ++CV
Sbjct: 679 LAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLF-GKSYKECV 730
Score = 79.0 bits (186), Expect = 1e-12
Identities = 77/300 (25%), Positives = 142/300 (47%), Gaps = 51/300 (17%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMPTT---------PTVESTEVIFTGIYTFE 180
+RR I+ H F FI+ IL++ + +E + +FT I+ E
Sbjct: 1020 LRRACFKIVEHNWFETFIVFMILLSSGALAFEDIYIEQRRVIRTILEYADKVFTYIFIME 1079
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI------DLGNLAALRTFRVLR 234
+K +A GF + Y +AW WLDF+++ ++ +++ +LG + +LRT R LR
Sbjct: 1080 MLLKWVAYGFKV----YFTNAWCWLDFLIVDVSIISLVANWLGYSELGPIKSLRTLRALR 1135
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFP 294
L+ ++ G++ +V A++ ++ ++ +V+++ + +F++MG+ ++ G C+
Sbjct: 1136 PLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKF-YYCI---- 1190
Query: 295 EDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGY 354
N T ERF +E N E C + GQ ++ ++ N GY
Sbjct: 1191 ------NTTTS--ERFDISEVNNKSE------CESLMHTGQVR--WLNVKVNYDNVGLGY 1234
Query: 355 TSF---DTF-GW-----AFLSAFRLMTQDYWE-NLYQ-LFFVVIIFLGSFYLVNLILAIV 403
S TF GW A + + Q +E NLY L+FV+ I GSF+ +NL + ++
Sbjct: 1235 LSLLQVATFKGWMDIMYAAVDSREKEEQPQYEVNLYMYLYFVIFIIFGSFFTLNLFIGVI 1294
Score = 76.6 bits (180), Expect = 7e-12
Identities = 30/58 (51%), Positives = 43/58 (74%)
Query: 774 VWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGN 831
+W+CC WL+F+ + L+V DPFV+L IT+CIV+NTLFMA++H+ M + D L GN
Sbjct: 557 IWNCCAPWLKFKNIIHLIVMDPFVDLGITICIVLNTLFMAMEHYPMTEHFDNVLTVGN 614
Score = 74.1 bits (174), Expect = 3e-11
Identities = 50/179 (27%), Positives = 93/179 (51%), Gaps = 19/179 (10%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
+ +R K++ + F ++ IL + + + + D P +++ Y FT I+
Sbjct: 117 FSVVRRGAIKVLIHALFSMFIMITILTNCVFMTMSDPP----PWSKNVEY----TFTGIY 168
Query: 1264 FIEMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLR 1319
E LIK LA GF + + W WLDF ++M++ ++ G I A +T R LR
Sbjct: 169 TFESLIKILARGFCVDDFTFLRDPWNWLDFSVIMMA---YLTEFVDLGNISALRTFRVLR 225
Query: 1320 ALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKCV 1377
AL+ + + G++ +V AL+Q++ + +V+++ + +FA++G+QLF G KCV
Sbjct: 226 ALKTITVIP---GLKTIVGALIQSVKKLSDVMILTVFCLSVFALVGLQLFMGNLRQKCV 281
Score = 54.4 bits (125), Expect = 3e-05
Identities = 43/156 (27%), Positives = 75/156 (48%), Gaps = 20/156 (12%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY----- 1592
F M IM+ I N + MT+ +S ++Y F I++ E L+KI A +
Sbjct: 133 FSMFIMITILTNCVFMTMS---DPPPWSKNVEYT---FTGIYTFESLIKILARGFCVDDF 186
Query: 1593 HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIR 1652
+ +PWN DF V+M + L+ FV + +R +V R L+ + G++
Sbjct: 187 TFLRDPWNWLDFSVIMMAYLT---------EFVDLGNISALRTFRVLRALKTITVIPGLK 237
Query: 1653 TLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
T++ AL S+ L ++ +L + +FA+ G+ FM
Sbjct: 238 TIVGALIQSVKKLSDVMILTVFCLSVFALVGLQLFM 273
Score = 44.4 bits (100), Expect = 0.032
Identities = 39/169 (23%), Positives = 82/169 (48%), Gaps = 21/169 (12%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVE-------STEVIFTGIYT 178
P N I+ + ++ F + I+ I +N + M++ T + + +IF I+T
Sbjct: 1338 PQNKIQGMVYDLVTKQAFDITIMILICLNMVTMMVETDDQSQLKVDILYNINMIFIIIFT 1397
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGN--------LAALRT 229
E +K++A L+ + Y WN DFVV+ L+ V + + DL +R
Sbjct: 1398 GECVLKMLA----LRQY-YFTVGWNIFDFVVVILSIVGLALSDLIQKYFVSPTLFRVIRL 1452
Query: 230 FRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGL 278
R+ R L+ + G++T++ A++ S+ L ++ +L + ++++ G+
Sbjct: 1453 ARIGRVLRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGM 1501
Score = 37.5 bits (83), Expect = 3.7
Identities = 29/140 (20%), Positives = 65/140 (46%), Gaps = 6/140 (4%)
Query: 776 DCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRV 835
+C L ++Y + ++ F + + L IV L + + + + + ++ RV
Sbjct: 1399 ECVLKMLALRQYYFTVGWNIFDFVVVILSIVGLALSDLIQKYFVSPTLFRVIRLARIGRV 1458
Query: 836 FKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDG 895
+L + + L+ + ++ AL N+ +L +++FI+++ GM F YV + G
Sbjct: 1459 LRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMSNFA-----YVKK-ESG 1512
Query: 896 DLPRWNFTDFMHSFMIVFRV 915
+NF F +S + +F +
Sbjct: 1513 IDDMFNFETFGNSIICLFEI 1532
>UniRef50_UPI0000ECCB92 Cluster: Voltage-gated sodium channel H; n=8;
Gallus gallus|Rep: Voltage-gated sodium channel H -
Gallus gallus
Length = 2032
Score = 842 bits (2083), Expect = 0.0
Identities = 413/748 (55%), Positives = 539/748 (72%), Gaps = 16/748 (2%)
Query: 1177 PADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALA 1236
P DC PE C + FP + D + W LR ++++E+ +FET +I MILLSS ALA
Sbjct: 1181 PEDCFPEVCVRFFPCCSVDISKFPGKIWWRLRKTCYRIVEHNWFETFIIFMILLSSGALA 1240
Query: 1237 LEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSL 1296
ED++L R ++ +L Y D+IFT IF +EML+KW+A GF+KYFTNAWCWLDF+IV VSL
Sbjct: 1241 FEDIYLEDRKNIKTMLEYADKIFTYIFVLEMLLKWVAYGFKKYFTNAWCWLDFLIVDVSL 1300
Query: 1297 INFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLI 1356
I+ +A G + K++RTLRALRPLRA+SR +GMRVVVNALV AIPSI NVLLVCLI
Sbjct: 1301 ISLIANTLGYSEMGPIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLI 1360
Query: 1357 FWLIFAIMGVQLFAGKYFKCVDMNH--TTLSHEIIPDKNACTLEN----YTWENSPMNFD 1410
FWLIF+IMGV LFAGK+ KC++ L +II + C L N + W +NFD
Sbjct: 1361 FWLIFSIMGVNLFAGKFGKCINKTEGDMPLDSKIINNMTDCILYNVSGTFYWTKVKVNFD 1420
Query: 1411 HVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLN 1470
+VG YL L QVATFKGW+ IM A+DSRE QP E N+YMYLY TLN
Sbjct: 1421 NVGAGYLALLQVATFKGWMDIMYAAVDSRECEEQPEWECNLYMYLYFVIFIIFGSFFTLN 1480
Query: 1471 LFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVF 1530
LFIGVIIDNFN+QKKK GG ++FMTE+QKKYYNAMKK+GSKKP K IPRP + Q +F
Sbjct: 1481 LFIGVIIDNFNQQKKKLGGQ-DIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKYQGFIF 1539
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL 1590
++V+ + FD+ IM+ I LNM+TM ++ QS+ +L +NM+F+ IF+ EC+ K+ AL
Sbjct: 1540 DVVSKQAFDVSIMILICLNMVTMMVETDDQSQEKVNILHKINMLFVAIFTGECIFKMLAL 1599
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
R++YF WN+FDFVVV+ SI+ VLSDII+KYF SPTL RV+R+A++GR+LRL++GAKG
Sbjct: 1600 RHYYFTNGWNIFDFVVVILSIVGTVLSDIIQKYFFSPTLFRVIRLARIGRILRLIRGAKG 1659
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMI 1710
IRTLLFAL MSLPALFNI LLLFLVMFI+AIFGM+ F +VK + G+DD++NF+TF SM+
Sbjct: 1660 IRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMANFAYVKKEYGIDDMFNFQTFANSML 1719
Query: 1711 LLFQMSTSAGWDGVLDGIIN--EEECD--LPDNERGSPGNCGSATIGITYLLSYLVISFL 1766
LFQ++TSAGWDG+L+ I+N CD LP N GS G+CGS +GI + ++Y++ISFL
Sbjct: 1720 CLFQITTSAGWDGLLNPILNTGPPYCDPNLP-NANGSKGDCGSPAVGILFFVTYIIISFL 1778
Query: 1767 IVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVL 1826
IV+NMYIA+ILEN+S ATE+ E L++DD+DM+YEIW++FDP+ +Q+I Y LSDF D L
Sbjct: 1779 IVVNMYIAIILENFSVATEESTEPLSEDDFDMFYEIWEKFDPEATQFIEYSALSDFADAL 1838
Query: 1827 EPPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTKDFFARKGN----PIEETGDLEV 1882
PL+I KPNK K+I+MD+P+ GD + C+DIL A TK G I+
Sbjct: 1839 SEPLRIAKPNKIKLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALKIQMEEKFMA 1898
Query: 1883 GRPEEAGYEPVSSTLWRQREEYCARLIQ 1910
P + YEP+++TL R++EE A +IQ
Sbjct: 1899 ANPSKISYEPITTTLRRKQEEVSAIVIQ 1926
Score = 419 bits (1033), Expect = e-115
Identities = 222/412 (53%), Positives = 280/412 (67%), Gaps = 30/412 (7%)
Query: 16 FRPFTRESLXXXXXXXXXXXXKQKELEKKRAEGEVRYXXXXXXXGPQPDATLEQGLPLPV 75
F FT ESL + + E + GE PQP L+ LP
Sbjct: 13 FHRFTPESLAAIEKRIAEKLARNAKQEYREQLGEEEK--------PQPQFDLQACKKLP- 63
Query: 76 RMQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNALWILDPFNPIRRVAI 135
+ G+ P EL PLEDIDPFY+++ TFVV++KGK IFRFSAT AL+IL PF+P+RR AI
Sbjct: 64 DIYGTVPPELIGEPLEDIDPFYNDRKTFVVLNKGKTIFRFSATPALYILSPFHPVRRAAI 123
Query: 136 YILVHPLFSLFIITTILVNCILMIMPTTPTVES-TEVIFTGIYTFESAVKVMARGFILQP 194
IL+ LFS+FI+ TIL NC+ M TP+ E FTGIYTFES +K++ARGF +
Sbjct: 124 KILLFTLFSMFIMCTILTNCVFMAQSETPSWNKYVEYTFTGIYTFESLIKILARGFCMTE 183
Query: 195 FTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIE 254
FT+LRD WNWLDF VI +AY+T +DLGN++ALRTFRVLRALKT++++ GLKTIVGA+I+
Sbjct: 184 FTFLRDPWNWLDFSVIVMAYITEFVDLGNVSALRTFRVLRALKTISVISGLKTIVGALIQ 243
Query: 255 SVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPE----DGS--WGNLTDENWE 308
SVK L DV+ILT+F LSVFAL+GLQ++MG L KCV+ + + +GS T N E
Sbjct: 244 SVKKLADVMILTVFCLSVFALIGLQLFMGNLRHKCVRDYTQFNFTNGSLYLDGRTWNNSE 303
Query: 309 RFCQNETNWYGEGG--DYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLS 366
F + N++ + G D LCGNS+ AG C GY+CL+ G NP++GYTSFDTFGWAFLS
Sbjct: 304 EFLNDPVNYFIKNGTEDVLLCGNSTDAGTCPEGYICLKA-GENPDHGYTSFDTFGWAFLS 362
Query: 367 AFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
FRLMTQDYWE LYQ LFF+++IFLGSFYLVNLILA+VAM+Y
Sbjct: 363 LFRLMTQDYWERLYQQTLRSAGKIYMLFFMLVIFLGSFYLVNLILAVVAMAY 414
Score = 183 bits (445), Expect = 5e-44
Identities = 88/176 (50%), Positives = 112/176 (63%), Gaps = 2/176 (1%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+S LRVFKLAKSWPTLN LI I+G ++GALGNLT VL II+FIFAV+GMQLFGK+Y+
Sbjct: 816 LRSFRLLRVFKLAKSWPTLNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYL 875
Query: 887 DYVDRF-PDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCM-LVGDVSCIPFFLATVV 944
D V + G+LPRW+ DF HSF+I+FR+LCGEWIE+MWDCM + G C+ FL +V
Sbjct: 876 DNVKKISTTGNLPRWHMNDFFHSFLIIFRILCGEWIETMWDCMEVAGQPLCLLVFLLVMV 935
Query: 945 IXXXXXXXXXXXXXXXXXXXXXXXTPTADQDTNKIAEAFNRISRFIDWIKRNVADF 1000
I P D + N + AF RI+R + ++K DF
Sbjct: 936 IGNLVVLNLFLALLLSSFSADNLSAPDEDGEMNNLQLAFARINRGLQYVKHTTWDF 991
Score = 102 bits (244), Expect = 1e-19
Identities = 86/306 (28%), Positives = 156/306 (50%), Gaps = 36/306 (11%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL- 1590
+V D D+ I L I LN L M L+HY+ ++ F +L N++F IF++E + K+ AL
Sbjct: 722 VVMDPFTDLTITLCIVLNTLFMALEHYKMTKEFDHMLYIGNLVFTGIFTAEMIFKVIALD 781
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
Y+YF + WN+FD ++V+ S++ L LS S L V+R ++ RV +L K
Sbjct: 782 PYYYFQQGWNIFDSIIVILSLMELGLS--------SMGNLSVLRSFRLLRVFKLAKSWPT 833
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAI-----FGMSFFMHVKDKGGLDDV--YNFK 1703
+ TL+ + S+ AL N+ L+L +++FIFA+ FG S+ +VK ++ ++
Sbjct: 834 LNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYLDNVKKISTTGNLPRWHMN 893
Query: 1704 TFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVI 1763
F S +++F+ +L G E D + G P + + L +VI
Sbjct: 894 DFFHSFLIIFR---------ILCGEWIETMWDCME-VAGQP-------LCLLVFLLVMVI 936
Query: 1764 SFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFL 1823
L+V+N+++A++L ++S +++ D + + + R + G QY+++
Sbjct: 937 GNLVVLNLFLALLLSSFS--ADNLSAPDEDGEMNNLQLAFARIN-RGLQYVKHTTWDFCC 993
Query: 1824 DVLEPP 1829
+VL P
Sbjct: 994 NVLRHP 999
Score = 83.0 bits (196), Expect = 7e-14
Identities = 69/291 (23%), Positives = 132/291 (45%), Gaps = 32/291 (10%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMPTT---------PTVESTEVIFTGIYTFE 180
+R+ I+ H F FII IL++ + +E + IFT I+ E
Sbjct: 1211 LRKTCYRIVEHNWFETFIIFMILLSSGALAFEDIYLEDRKNIKTMLEYADKIFTYIFVLE 1270
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV-----TMGI-DLGNLAALRTFRVLR 234
+K +A GF Y +AW WLDF+++ ++ + T+G ++G + +LRT R LR
Sbjct: 1271 MLLKWVAYGFK----KYFTNAWCWLDFLIVDVSLISLIANTLGYSEMGPIKSLRTLRALR 1326
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFP 294
L+ ++ G++ +V A++ ++ ++ +V+++ + +F++MG+ ++ G KC+
Sbjct: 1327 PLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKF-GKCINKTE 1385
Query: 295 EDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGY 354
D + N + Y G + GY+ L +
Sbjct: 1386 GDMPLDSKIINN-----MTDCILYNVSGTFYWTKVKVNFDNVGAGYLALLQVAT-----F 1435
Query: 355 TSFDTFGWAFLSAFRLMTQDYWE-NLYQ-LFFVVIIFLGSFYLVNLILAIV 403
+ +A + + Q WE NLY L+FV+ I GSF+ +NL + ++
Sbjct: 1436 KGWMDIMYAAVDSRECEEQPEWECNLYMYLYFVIFIIFGSFFTLNLFIGVI 1486
Score = 82.6 bits (195), Expect = 1e-13
Identities = 34/60 (56%), Positives = 43/60 (71%)
Query: 772 FCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGN 831
F +WDCC WL +K+V +V DPF +L ITLCIV+NTLFMAL+H+ M K+ D L GN
Sbjct: 703 FLIWDCCPFWLLIKKFVKFVVMDPFTDLTITLCIVLNTLFMALEHYKMTKEFDHMLYIGN 762
Score = 81.8 bits (193), Expect = 2e-13
Identities = 48/176 (27%), Positives = 93/176 (52%), Gaps = 13/176 (7%)
Query: 115 FSATNALWILDPF-NPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTE--- 170
F+ +W PF I++ ++++ P L I I++N + M + + +
Sbjct: 699 FAVKFLIWDCCPFWLLIKKFVKFVVMDPFTDLTITLCIVLNTLFMALEHYKMTKEFDHML 758
Query: 171 ----VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID-LGNLA 225
++FTGI+T E KV+A L P+ Y + WN D +++ L+ + +G+ +GNL+
Sbjct: 759 YIGNLVFTGIFTAEMIFKVIA----LDPYYYFQQGWNIFDSIIVILSLMELGLSSMGNLS 814
Query: 226 ALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
LR+FR+LR K P L T++ + SV L ++ ++ + +FA++G+Q++
Sbjct: 815 VLRSFRLLRVFKLAKSWPTLNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLF 870
Score = 81.0 bits (191), Expect = 3e-13
Identities = 55/158 (34%), Positives = 87/158 (55%), Gaps = 18/158 (11%)
Query: 1254 YMDRIFTVIFFIEMLIKWLALGF-QKYFT---NAWCWLDF-IIVMVSLINFVAALCGAGG 1308
Y++ FT I+ E LIK LA GF FT + W WLDF +IVM + FV G
Sbjct: 157 YVEYTFTGIYTFESLIKILARGFCMTEFTFLRDPWNWLDFSVIVMAYITEFV----DLGN 212
Query: 1309 IQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQL 1368
+ A +T R LRAL+ + +S G++ +V AL+Q++ + +V+++ + +FA++G+QL
Sbjct: 213 VSALRTFRVLRALKTISVIS---GLKTIVGALIQSVKKLADVMILTVFCLSVFALIGLQL 269
Query: 1369 FAGKY-FKCVDMNHTTLSHEIIPDKNACTLENYTWENS 1405
F G KCV ++T + + L+ TW NS
Sbjct: 270 FMGNLRHKCV-RDYTQFNF----TNGSLYLDGRTWNNS 302
Score = 75.8 bits (178), Expect = 1e-11
Identities = 64/207 (30%), Positives = 96/207 (46%), Gaps = 18/207 (8%)
Query: 1181 CPEQCYQKFP--FLAGDDDSPFWQGWGTLRLKTF-KLIENTYFETAVITM-ILLSSLALA 1236
CP C+ F FL D PFW L +K F K + F IT+ I+L++L +A
Sbjct: 692 CPP-CWNHFAVKFLIWDC-CPFW-----LLIKKFVKFVVMDPFTDLTITLCIVLNTLFMA 744
Query: 1237 LEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSL 1296
LE H +LY + +FT IF EM+ K +AL YF W D IIV++SL
Sbjct: 745 LE--HYKMTKEFDHMLYIGNLVFTGIFTAEMIFKVIALDPYYYFQQGWNIFDSIIVILSL 802
Query: 1297 INFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLI 1356
+ G + +R+ R LR + + ++ + ++ ++ N+ LV I
Sbjct: 803 MEL-----GLSSMGNLSVLRSFRLLRVFKLAKSWPTLNTLIKIIGNSVGALGNLTLVLAI 857
Query: 1357 FWLIFAIMGVQLFAGKYFKCVDMNHTT 1383
IFA++G+QLF Y V TT
Sbjct: 858 IVFIFAVVGMQLFGKSYLDNVKKISTT 884
Score = 54.8 bits (126), Expect = 2e-05
Identities = 47/156 (30%), Positives = 75/156 (48%), Gaps = 20/156 (12%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFA-----LRY 1592
F M IM I N + M QSET S Y+ F I++ E L+KI A +
Sbjct: 131 FSMFIMCTILTNCVFMA-----QSETPSWN-KYVEYTFTGIYTFESLIKILARGFCMTEF 184
Query: 1593 HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIR 1652
+ +PWN DF V+ V++ I E FV + +R +V R L+ + G++
Sbjct: 185 TFLRDPWNWLDFSVI-------VMAYITE--FVDLGNVSALRTFRVLRALKTISVISGLK 235
Query: 1653 TLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
T++ AL S+ L ++ +L + +FA+ G+ FM
Sbjct: 236 TIVGALIQSVKKLADVMILTVFCLSVFALIGLQLFM 271
Score = 42.3 bits (95), Expect = 0.13
Identities = 38/169 (22%), Positives = 79/169 (46%), Gaps = 21/169 (12%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPT-------VESTEVIFTGIYT 178
P N + ++ F + I+ I +N + M++ T + ++F I+T
Sbjct: 1530 PLNKYQGFIFDVVSKQAFDVSIMILICLNMVTMMVETDDQSQEKVNILHKINMLFVAIFT 1589
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV-TMGIDLGN--------LAALRT 229
E K++A L+ + Y + WN DFVV+ L+ V T+ D+ +R
Sbjct: 1590 GECIFKMLA----LRHY-YFTNGWNIFDFVVVILSIVGTVLSDIIQKYFFSPTLFRVIRL 1644
Query: 230 FRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGL 278
R+ R L+ + G++T++ A++ S+ L ++ +L + ++A+ G+
Sbjct: 1645 ARIGRILRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGM 1693
Score = 38.3 bits (85), Expect = 2.1
Identities = 28/140 (20%), Positives = 63/140 (45%), Gaps = 6/140 (4%)
Query: 776 DCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRV 835
+C + L + Y ++ F + + L IV L + + + + ++ R+
Sbjct: 1591 ECIFKMLALRHYYFTNGWNIFDFVVVILSIVGTVLSDIIQKYFFSPTLFRVIRLARIGRI 1650
Query: 836 FKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDG 895
+L + + L+ + ++ AL N+ +L +++FI+A+ GM F +Y G
Sbjct: 1651 LRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMANFAYVKKEY------G 1704
Query: 896 DLPRWNFTDFMHSFMIVFRV 915
+NF F +S + +F++
Sbjct: 1705 IDDMFNFQTFANSMLCLFQI 1724
>UniRef50_P08104 Cluster: Sodium channel protein type 3 subunit alpha;
n=50; Euteleostomi|Rep: Sodium channel protein type 3
subunit alpha - Rattus norvegicus (Rat)
Length = 1951
Score = 837 bits (2070), Expect = 0.0
Identities = 412/750 (54%), Positives = 543/750 (72%), Gaps = 16/750 (2%)
Query: 1174 DDTPADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSL 1233
D P C E C +KFPF + + W LR + ++E+ +FET ++ MILLSS
Sbjct: 1113 DLKPEACFTEGCIKKFPFCQVSTEEGKGKIWWNLRKTCYSIVEHNWFETFIVFMILLSSG 1172
Query: 1234 ALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVM 1293
ALA ED+++ R ++ +L Y D++FT IF +EML+KW+A GFQ YFTNAWCWLDF+IV
Sbjct: 1173 ALAFEDIYIEQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGFQTYFTNAWCWLDFLIVD 1232
Query: 1294 VSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLV 1353
VSL++ VA G + A K++RTLRALRPLRA+SR +GMRVVVNALV AIPSI NVLLV
Sbjct: 1233 VSLVSLVANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLV 1292
Query: 1354 CLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNA---CTL--ENYTWENSPMN 1408
CLIFWLIF+IMGV LFAGK++ CV N TT + I + N C + W+N +N
Sbjct: 1293 CLIFWLIFSIMGVNLFAGKFYHCV--NTTTGNMFEIKEVNNFSDCQALGKQARWKNVKVN 1350
Query: 1409 FDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXT 1468
FD+VG YL L QVATFKGW+ IM A+DSR+V QPI E N+YMYLY T
Sbjct: 1351 FDNVGAGYLALLQVATFKGWMDIMYAAVDSRDVKLQPIYEENLYMYLYFVIFIIFGSFFT 1410
Query: 1469 LNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAI 1528
LNLFIGVIIDNFN+QKKK GG ++FMTE+QKKYYNAMKK+GSKKP K IPRP + Q +
Sbjct: 1411 LNLFIGVIIDNFNQQKKKFGGQ-DIFMTEEQKKYYNAMKKLGSKKPQKPIPRPANKFQGM 1469
Query: 1529 VFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIF 1588
VF+ VT + FD+ IM+ I LNM+TM ++ QS+ + VL +N++FIV+F+ E LLK+
Sbjct: 1470 VFDFVTRQVFDISIMILICLNMVTMMVETDDQSKYMTLVLSRINLVFIVLFTGEFLLKLI 1529
Query: 1589 ALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGA 1648
+LRY+YF WN+FDFVVV+ SI+ + L+++IEKYFVSPTL RV+R+A++GR+LRL+KGA
Sbjct: 1530 SLRYYYFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRLARIGRILRLIKGA 1589
Query: 1649 KGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQS 1708
KGIRTLLFAL MSLPALFNI LLLFLVMFI+AIFGMS F +VK + G+DD++NF+TF S
Sbjct: 1590 KGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKKEAGIDDMFNFETFGNS 1649
Query: 1709 MILLFQMSTSAGWDGVLDGIINE--EECDLPDNERGS--PGNCGSATIGITYLLSYLVIS 1764
MI LFQ++TSAGWDG+L I+N +CD GS G+CG+ ++GI + +SY++IS
Sbjct: 1650 MICLFQITTSAGWDGLLAPILNSAPPDCDPDAIHPGSSVKGDCGNPSVGIFFFVSYIIIS 1709
Query: 1765 FLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLD 1824
FL+V+NMYIAVILEN+S ATE+ E L++DD++M+YE+W++FDPD +Q+I + +LSDF
Sbjct: 1710 FLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFIEFCKLSDFAA 1769
Query: 1825 VLEPPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTKDFFARKGN----PIEETGDL 1880
L+PPL I KPNK ++I+MD+P+ GD + C+DIL A TK G I+
Sbjct: 1770 ALDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRIQMEDRF 1829
Query: 1881 EVGRPEEAGYEPVSSTLWRQREEYCARLIQ 1910
P + YEP+++TL R++EE A +IQ
Sbjct: 1830 MASNPSKVSYEPITTTLKRKQEEVSAAIIQ 1859
Score = 429 bits (1056), Expect = e-118
Identities = 227/426 (53%), Positives = 293/426 (68%), Gaps = 46/426 (10%)
Query: 16 FRPFTRESLXXXXXXXXXXXXKQKELEKKRAEGEVRYXXXXXXXGPQPDATLEQGLPLPV 75
FR FTRESL +K +++A+ + P+P++ LE G LP
Sbjct: 14 FRLFTRESLAAI----------EKRAAEEKAKKPKKEQDIDDENKPKPNSDLEAGKNLPF 63
Query: 76 RMQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNALWILDPFNPIRRVAI 135
+ G P E+ S PLED+DP+Y ++ TFVV++KGK IFRFSAT+AL+IL P NP+R++AI
Sbjct: 64 -IYGDIPPEMVSEPLEDLDPYYVSKKTFVVLNKGKAIFRFSATSALYILTPLNPVRKIAI 122
Query: 136 YILVHPLFSLFIITTILVNCILMIMPTTPT-VESTEVIFTGIYTFESAVKVMARGFILQP 194
ILVH LFS+ I+ TIL NC+ M + P ++ E FTGIYTFES +K++ARGF L+
Sbjct: 123 KILVHSLFSMLIMCTILTNCVFMTLSNPPDWTKNVEYTFTGIYTFESLIKILARGFCLED 182
Query: 195 FTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIE 254
FT+LRD WNWLDF VI +AYVT +DLGN++ALRTFRVLRALKT++++PGLKTIVGA+I+
Sbjct: 183 FTFLRDPWNWLDFSVIVMAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQ 242
Query: 255 SVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPED------------------ 296
SVK L DV+ILT+F LSVFAL+GLQ++MG L KC + P D
Sbjct: 243 SVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCSQWPPSDSAFETNTTSYFNGTMDSN 302
Query: 297 GSWGNLTDE--NWERFCQNETNWYGEGG--DYPLCGNSSGAGQCEPGYVCLQGFGPNPNY 352
G++ N+T NW+ + +++++Y G D LCGN S AGQC GY+C++ G NPNY
Sbjct: 303 GTFVNVTMSTFNWKDYIADDSHFYVLDGQKDPLLCGNGSDAGQCPEGYICVKA-GRNPNY 361
Query: 353 GYTSFDTFGWAFLSAFRLMTQDYWENLYQL-----------FFVVIIFLGSFYLVNLILA 401
GYTSFDTF WAFLS FRLMTQDYWENLYQL FFV++IFLGSFYLVNLILA
Sbjct: 362 GYTSFDTFSWAFLSLFRLMTQDYWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLVNLILA 421
Query: 402 IVAMSY 407
+VAM+Y
Sbjct: 422 VVAMAY 427
Score = 176 bits (428), Expect = 6e-42
Identities = 93/229 (40%), Positives = 130/229 (56%), Gaps = 4/229 (1%)
Query: 805 IVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTF 864
I+V+ M L N++ L+S LRVFKLAKSWPTLN+LI I+G ++GALGNLT
Sbjct: 781 IIVSLSLMELGLANVEGL--SVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTL 838
Query: 865 VLCIIIFIFAVMGMQLFGKNYVDYVDRF-PDGDLPRWNFTDFMHSFMIVFRVLCGEWIES 923
VL II+FIFAV+GMQLFGK+Y + V + D LPRW+ DF HSF+IVFRVLCGEWIE+
Sbjct: 839 VLAIIVFIFAVVGMQLFGKSYKECVCKINVDCKLPRWHMNDFFHSFLIVFRVLCGEWIET 898
Query: 924 MWDCM-LVGDVSCIPFFLATVVIXXXXXXXXXXXXXXXXXXXXXXXTPTADQDTNKIAEA 982
MWDCM + G C+ F+ +VI D + N + A
Sbjct: 899 MWDCMEVAGQTMCLIVFMLVMVIGNLVVLNLFLALLLSSFSSDNLAATDDDNEMNNLQIA 958
Query: 983 FNRISRFIDWIKRNVADFLKLLKNKLTNQIAIHAPERVDNELELGTDLD 1031
R+ + ID++K + + + + I I ++D+ + T ++
Sbjct: 959 VGRMQKGIDFVKNKIRECFRKAFFRKPKVIEIQEGNKIDSCMSNNTGIE 1007
Score = 103 bits (247), Expect = 5e-20
Identities = 83/275 (30%), Positives = 146/275 (53%), Gaps = 37/275 (13%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL- 1590
IV D D+ I + I LN L M ++HY ++ FS+VL N++F IF++E +LKI A+
Sbjct: 707 IVMDPFVDLAITICIVLNTLFMAMEHYPMTQQFSSVLTVGNLVFTGIFTAEMVLKIIAMD 766
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
Y+YF E WN+FD ++V S++ L L+++ L V+R ++ RV +L K
Sbjct: 767 PYYYFQEGWNIFDGIIVSLSLMELGLANV--------EGLSVLRSFRLLRVFKLAKSWPT 818
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF-MHVKD---KGGLD---DVYNFK 1703
+ L+ + S+ AL N+ L+L +++FIFA+ GM F K+ K +D ++
Sbjct: 819 LNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKINVDCKLPRWHMN 878
Query: 1704 TFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVI 1763
F S +++F+ VL G E D + T+ + + +VI
Sbjct: 879 DFFHSFLIVFR---------VLCGEWIETMWDCME--------VAGQTMCLIVFMLVMVI 921
Query: 1764 SFLIVINMYIAVILENYSQATEDVQEGLTDDDYDM 1798
L+V+N+++A++L ++S ++++ TDDD +M
Sbjct: 922 GNLVVLNLFLALLLSSFS--SDNL--AATDDDNEM 952
Score = 83.0 bits (196), Expect = 7e-14
Identities = 50/187 (26%), Positives = 101/187 (54%), Gaps = 14/187 (7%)
Query: 113 FRFSATNALW-ILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM---PTTPTVES 168
+RF+ +W D + ++ + I++ P L I I++N + M M P T S
Sbjct: 682 YRFANVFLIWDCCDAWLKVKHLVNLIVMDPFVDLAITICIVLNTLFMAMEHYPMTQQFSS 741
Query: 169 T----EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGN 223
++FTGI+T E +K++A + P+ Y ++ WN D ++++L+ + +G+ ++
Sbjct: 742 VLTVGNLVFTGIFTAEMVLKIIA----MDPYYYFQEGWNIFDGIIVSLSLMELGLANVEG 797
Query: 224 LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
L+ LR+FR+LR K P L ++ + SV L ++ ++ + +FA++G+Q++ G
Sbjct: 798 LSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLF-G 856
Query: 284 VLTQKCV 290
++CV
Sbjct: 857 KSYKECV 863
Score = 83.0 bits (196), Expect = 7e-14
Identities = 74/293 (25%), Positives = 139/293 (47%), Gaps = 39/293 (13%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMP--------TTPTV-ESTEVIFTGIYTFE 180
+R+ I+ H F FI+ IL++ + T T+ E + +FT I+ E
Sbjct: 1146 LRKTCYSIVEHNWFETFIVFMILLSSGALAFEDIYIEQRKTIKTMLEYADKVFTYIFILE 1205
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI------DLGNLAALRTFRVLR 234
+K +A GF TY +AW WLDF+++ ++ V++ +LG + +LRT R LR
Sbjct: 1206 MLLKWVAYGFQ----TYFTNAWCWLDFLIVDVSLVSLVANALGYSELGAIKSLRTLRALR 1261
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFP 294
L+ ++ G++ +V A++ ++ ++ +V+++ + +F++MG+ ++ G CV
Sbjct: 1262 PLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKF-YHCVNT-- 1318
Query: 295 EDGSWGNLTDENWERFCQ---NETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPN 351
G+ + + N CQ + W ++ ++ GA GY+ L
Sbjct: 1319 TTGNMFEIKEVNNFSDCQALGKQARWKNVKVNF----DNVGA-----GYLALLQVATFKG 1369
Query: 352 YGYTSFDTFGWAFLSAFRLMTQDYWENLYQ-LFFVVIIFLGSFYLVNLILAIV 403
+ D A S + Y ENLY L+FV+ I GSF+ +NL + ++
Sbjct: 1370 W----MDIMYAAVDSRDVKLQPIYEENLYMYLYFVIFIIFGSFFTLNLFIGVI 1418
Score = 81.4 bits (192), Expect = 2e-13
Identities = 39/108 (36%), Positives = 65/108 (60%), Gaps = 5/108 (4%)
Query: 724 EIIEQAGRQSRASELNVSVYYFPTAEDDEDGPTFKEKLLDCLMKGIDFFCVWDCCWLWLE 783
E++E + + R+ ++++ T E+ E+ ++K C + + F +WDCC WL+
Sbjct: 645 EMLEDSSGRQRS--MSIASILTNTMEELEES---RQKCPPCWYRFANVFLIWDCCDAWLK 699
Query: 784 FQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGN 831
+ V L+V DPFV+L IT+CIV+NTLFMA++H+ M + L GN
Sbjct: 700 VKHLVNLIVMDPFVDLAITICIVLNTLFMAMEHYPMTQQFSSVLTVGN 747
Score = 78.6 bits (185), Expect = 2e-12
Identities = 45/164 (27%), Positives = 84/164 (51%), Gaps = 7/164 (4%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
++ + + + A+ I+L++L +A+E H P +L + +FT IF EM++K +A
Sbjct: 707 IVMDPFVDLAITICIVLNTLFMAME--HYPMTQQFSSVLTVGNLVFTGIFTAEMVLKIIA 764
Query: 1274 LGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGM 1333
+ YF W D IIV +SL+ G ++ +R+ R LR + +
Sbjct: 765 MDPYYYFQEGWNIFDGIIVSLSLMEL-----GLANVEGLSVLRSFRLLRVFKLAKSWPTL 819
Query: 1334 RVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCV 1377
+++ + ++ ++ N+ LV I IFA++G+QLF Y +CV
Sbjct: 820 NMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECV 863
Score = 72.5 bits (170), Expect = 1e-10
Identities = 39/117 (33%), Positives = 69/117 (58%), Gaps = 10/117 (8%)
Query: 1259 FTVIFFIEMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKT 1314
FT I+ E LIK LA GF + + W WLDF +++++ +V G + A
Sbjct: 161 FTGIYTFESLIKILARGFCLEDFTFLRDPWNWLDFSVIVMA---YVTEFVDLGNVSA--- 214
Query: 1315 MRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
+RT R LR L+ +S + G++ +V AL+Q++ + +V+++ + +FA++G+QLF G
Sbjct: 215 LRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMG 271
Score = 55.2 bits (127), Expect = 2e-05
Identities = 47/166 (28%), Positives = 82/166 (49%), Gaps = 20/166 (12%)
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKI 1587
I +I+ F M+IM I N + MTL + ++ ++Y F I++ E L+KI
Sbjct: 120 IAIKILVHSLFSMLIMCTILTNCVFMTLSN---PPDWTKNVEYT---FTGIYTFESLIKI 173
Query: 1588 ----FALRYHYFV-EPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVL 1642
F L F+ +PWN DF V+ V++ + E FV + +R +V R L
Sbjct: 174 LARGFCLEDFTFLRDPWNWLDFSVI-------VMAYVTE--FVDLGNVSALRTFRVLRAL 224
Query: 1643 RLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
+ + G++T++ AL S+ L ++ +L + +FA+ G+ FM
Sbjct: 225 KTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFM 270
Score = 41.5 bits (93), Expect = 0.23
Identities = 35/169 (20%), Positives = 77/169 (45%), Gaps = 21/169 (12%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT-------TPTVESTEVIFTGIYT 178
P N + + + +F + I+ I +N + M++ T T + ++F ++T
Sbjct: 1462 PANKFQGMVFDFVTRQVFDISIMILICLNMVTMMVETDDQSKYMTLVLSRINLVFIVLFT 1521
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM---------GIDLGNLAALRT 229
E +K+++ + Y WN DFVV+ L+ V M + +R
Sbjct: 1522 GEFLLKLISLRYY-----YFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRL 1576
Query: 230 FRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGL 278
R+ R L+ + G++T++ A++ S+ L ++ +L + ++A+ G+
Sbjct: 1577 ARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGM 1625
Score = 37.9 bits (84), Expect = 2.8
Identities = 29/140 (20%), Positives = 68/140 (48%), Gaps = 12/140 (8%)
Query: 800 FITLCIVVNTLFMA--LDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMG 857
F+ + + + +F+A ++ + + + + ++ R+ +L K + L+ + ++
Sbjct: 1545 FVVVILSIVGMFLAELIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLP 1604
Query: 858 ALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLC 917
AL N+ +L +++FI+A+ GM F YV + D +NF F +S + +F++
Sbjct: 1605 ALFNIGLLLFLVMFIYAIFGMSNFA-----YVKKEAGID-DMFNFETFGNSMICLFQIT- 1657
Query: 918 GEWIESMWDCMLVGDVSCIP 937
+ WD +L ++ P
Sbjct: 1658 ---TSAGWDGLLAPILNSAP 1674
>UniRef50_Q4S316 Cluster: Chromosome 3 SCAF14756, whole genome shotgun
sequence; n=2; Coelomata|Rep: Chromosome 3 SCAF14756,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1960
Score = 832 bits (2058), Expect = 0.0
Identities = 406/759 (53%), Positives = 543/759 (71%), Gaps = 25/759 (3%)
Query: 1177 PADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALA 1236
P C E C +F +++ ++ W TLR F ++E+ +FET +I MILLSS ALA
Sbjct: 1111 PEACFTEGCVSRFQCCQINEEGANYKSWWTLRKTCFIIVEHNWFETFIIFMILLSSGALA 1170
Query: 1237 LEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSL 1296
ED+++ R ++ +L Y D++FT +F +EML+KW+A GF KYFTNAWCWLDF+IV VSL
Sbjct: 1171 FEDIYIEQRRTIKTVLEYADKVFTYVFILEMLLKWVAYGFVKYFTNAWCWLDFLIVDVSL 1230
Query: 1297 INFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLI 1356
++ VA G + A K++RTLRALRPLRA+SR +GMRVVVNAL+ AIPSI NVLLVCLI
Sbjct: 1231 VSLVANALGYSELTAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLI 1290
Query: 1357 FWLIFAIMGVQLFAGKYFKCVDMN-HTTLSHEIIPDKNAC---TLENYTWENSPMNFDHV 1412
FWLIF+IMGV LFAGK+F C++ T E++ +K+ C ++ W N +NFD+V
Sbjct: 1291 FWLIFSIMGVNLFAGKFFYCMNTTTDETFPIEVVNNKSDCLNMVNQSARWNNIKINFDNV 1350
Query: 1413 GKAYLCLFQVATFKGWIQIMNDAIDSREV--GRQPIRETNIYMYLYXXXXXXXXXXXTLN 1470
G YL L QVATFKGW IM A+DSR+V G QP E N+YMYLY TLN
Sbjct: 1351 GAGYLALLQVATFKGWTDIMYAAVDSRDVSRGEQPKYEDNLYMYLYFVIFIIFGSFFTLN 1410
Query: 1471 LFIGVIIDNFNEQKKKAG-----------GSLEMFMTEDQKKYYNAMKKMGSKKPLKAIP 1519
LFIGVIIDNFN+QKKK G ++FMTE+QKKYYNAMKK+GSKKP K IP
Sbjct: 1411 LFIGVIIDNFNQQKKKISYNQMLRRCLYLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIP 1470
Query: 1520 RPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIF 1579
RP Q VF+ +T + FD++IM+ I LNM+TM ++ Q+E +L ++N++FIV+F
Sbjct: 1471 RPTNAFQGCVFDCITKQAFDIVIMILICLNMVTMMVETDDQTEEMGNILYWINVVFIVLF 1530
Query: 1580 SSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVG 1639
+ ECLLK+ +LR++YF WN+FDFVVV+ SI+ + LS++IEKYFVSPTLLRV+R+A++G
Sbjct: 1531 TGECLLKMISLRHYYFTIGWNVFDFVVVILSIMGMFLSEVIEKYFVSPTLLRVIRLARIG 1590
Query: 1640 RVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDV 1699
R+LRL+KGAKGIRTLLFAL MSLPALFNI LLLFLVMFI+AIFGMS F +VK + G+DD+
Sbjct: 1591 RILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKRESGIDDM 1650
Query: 1700 YNFKTFVQSMILLFQMSTSAGWDGVLDGIIN--EEECDLPDNERGS--PGNCGSATIGIT 1755
+NF+TF SMI LFQ++TS GWD +L I+N E +CD G+ GNCG+ ++GI
Sbjct: 1651 FNFETFGNSMICLFQITTSGGWDRLLAPILNKREPDCDSQLEHPGNSYKGNCGNPSVGIF 1710
Query: 1756 YLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIR 1815
+ +SY++I FLIV+NMYIAVILEN+S ATE+ E L++DD++M+YE+W+RFDPD +Q++
Sbjct: 1711 FFVSYIIICFLIVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWERFDPDATQFVE 1770
Query: 1816 YDQLSDFLDVLEPPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTKDFFARKGNPIE 1875
Y +LSDF D L+PPL++ KPN ++ISMD+P+ G+ + C+DIL A TK G
Sbjct: 1771 YSKLSDFADALDPPLRLPKPNMSQLISMDLPMVSGERIHCLDILFAFTKRVLGEGGEMDM 1830
Query: 1876 ETGDLE----VGRPEEAGYEPVSSTLWRQREEYCARLIQ 1910
G +E P + YEP+++TL R++EE A +IQ
Sbjct: 1831 LRGQMEERFMASNPSKVSYEPITTTLRRKQEEMSAVIIQ 1869
Score = 287 bits (703), Expect = 3e-75
Identities = 162/309 (52%), Positives = 205/309 (66%), Gaps = 44/309 (14%)
Query: 142 LFSLFIITTILVNCILMIMPTTPT-VESTEVIFTGIYTFESAVKVMARGFILQPFTYLRD 200
+FS+ I+ TIL NC M + P ++ E FTGIYTFES +K++ARGF + FT+LRD
Sbjct: 1 MFSMLIMFTILTNCAFMTLSNPPEWAKNVEYTFTGIYTFESLIKILARGFCVGKFTFLRD 60
Query: 201 AWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLR 260
WNWLDF VI +AYVT +DLGN++ALRTFRVLRALKT++++PGLKTIVGA+I+SVK L
Sbjct: 61 PWNWLDFSVILMAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLS 120
Query: 261 DVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFP-------------EDGSWGN--LTDE 305
DV+ILT+F LSVFAL+GLQ++MG L QKCV+ FP +D +G+ L +
Sbjct: 121 DVMILTVFCLSVFALIGLQLFMGNLRQKCVR-FPVSSNATNSTNGTADDMMFGSNFLLEL 179
Query: 306 NWERFCQ------NETNWYGEGGDY---PLCGNSSG--AGQCEPGYVCLQGF-----GPN 349
N F N T + + +Y P G G +C +GF G N
Sbjct: 180 NASVFLNTTEMPFNWTEYINDDRNYYYLPGLGRRDALLCGNGSGAGLCPEGFICIKAGRN 239
Query: 350 PNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNL 398
P+YGYTSFDTF WAFL+ FRLMTQDYWENLYQ +FFV++IFLGSFYLVNL
Sbjct: 240 PDYGYTSFDTFSWAFLTLFRLMTQDYWENLYQKTLRAAGKPYMIFFVLVIFLGSFYLVNL 299
Query: 399 ILAIVAMSY 407
ILA+VAM+Y
Sbjct: 300 ILAVVAMAY 308
Score = 175 bits (425), Expect = 1e-41
Identities = 91/200 (45%), Positives = 120/200 (60%), Gaps = 4/200 (2%)
Query: 805 IVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTF 864
I+V+ M L N++ L+S LRVFKLAKSWPTLN+LI I+G ++GALGNLT
Sbjct: 736 IIVSLSLMELGLANVEGL--SVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTL 793
Query: 865 VLCIIIFIFAVMGMQLFGKNYVDYVDRFPDG-DLPRWNFTDFMHSFMIVFRVLCGEWIES 923
VL II+FIFAV+GMQLFGK+Y + V + + +LPRW+ DF HSF+IVFRVLCGEWIE+
Sbjct: 794 VLAIIVFIFAVVGMQLFGKSYKECVCKISENCELPRWHMHDFFHSFLIVFRVLCGEWIET 853
Query: 924 MWDCM-LVGDVSCIPFFLATVVIXXXXXXXXXXXXXXXXXXXXXXXTPTADQDTNKIAEA 982
MWDCM + G C+ F+ +VI D + N + A
Sbjct: 854 MWDCMEVAGQSMCLIVFMMVMVIGNLVVLNLFLALLLSSFSADNLAATDEDSEMNNLQIA 913
Query: 983 FNRISRFIDWIKRNVADFLK 1002
RI R I ++K + FL+
Sbjct: 914 VGRIHRAIAFVKSTMTHFLQ 933
Score = 96.3 bits (229), Expect = 8e-18
Identities = 60/169 (35%), Positives = 95/169 (56%), Gaps = 14/169 (8%)
Query: 1521 PRW-RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIF 1579
P W + + +V +V D D+ I + I LN L M ++HY +E F VL +F IF
Sbjct: 654 PLWLKIKEVVSMVVMDPFVDLTITICIVLNTLFMAMEHYPMTEEFDNVLS----VFTGIF 709
Query: 1580 SSECLLKIFALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKV 1638
++E LKI AL Y+YF E WN+FD ++V S++ L L+++ L V+R ++
Sbjct: 710 TAEMCLKIIALHPYYYFQEGWNIFDGIIVSLSLMELGLANVEG--------LSVLRSFRL 761
Query: 1639 GRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
RV +L K + L+ + S+ AL N+ L+L +++FIFA+ GM F
Sbjct: 762 LRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLF 810
Score = 90.2 bits (214), Expect = 5e-16
Identities = 52/183 (28%), Positives = 102/183 (55%), Gaps = 10/183 (5%)
Query: 113 FRFSATNALWILDP-FNPIRRVAIYILVHPLFSLFIITTILVNCILMIM---PTTPTVES 168
+RF+ T +W P + I+ V +++ P L I I++N + M M P T ++
Sbjct: 641 YRFANTCLIWDCCPLWLKIKEVVSMVVMDPFVDLTITICIVLNTLFMAMEHYPMTEEFDN 700
Query: 169 TEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGNLAAL 227
+FTGI+T E +K++A L P+ Y ++ WN D ++++L+ + +G+ ++ L+ L
Sbjct: 701 VLSVFTGIFTAEMCLKIIA----LHPYYYFQEGWNIFDGIIVSLSLMELGLANVEGLSVL 756
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQ 287
R+FR+LR K P L ++ + SV L ++ ++ + +FA++G+Q++ G +
Sbjct: 757 RSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLF-GKSYK 815
Query: 288 KCV 290
+CV
Sbjct: 816 ECV 818
Score = 83.4 bits (197), Expect = 6e-14
Identities = 70/290 (24%), Positives = 136/290 (46%), Gaps = 30/290 (10%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMP--------TTPTV-ESTEVIFTGIYTFE 180
+R+ I+ H F FII IL++ + T TV E + +FT ++ E
Sbjct: 1141 LRKTCFIIVEHNWFETFIIFMILLSSGALAFEDIYIEQRRTIKTVLEYADKVFTYVFILE 1200
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI------DLGNLAALRTFRVLR 234
+K +A GF+ Y +AW WLDF+++ ++ V++ +L + +LRT R LR
Sbjct: 1201 MLLKWVAYGFV----KYFTNAWCWLDFLIVDVSLVSLVANALGYSELTAIKSLRTLRALR 1256
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFP 294
L+ ++ G++ +V A++ ++ ++ +V+++ + +F++MG+ ++ G C+
Sbjct: 1257 PLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFFY-CMNTTT 1315
Query: 295 EDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGY 354
++ + N + C N N + + ++ GA GY+ L G+
Sbjct: 1316 DETF--PIEVVNNKSDCLNMVNQSARWNNIKINFDNVGA-----GYLALLQVATFK--GW 1366
Query: 355 TSFDTFGWAFLSAFRLMTQDYWENLYQ-LFFVVIIFLGSFYLVNLILAIV 403
T R Y +NLY L+FV+ I GSF+ +NL + ++
Sbjct: 1367 TDIMYAAVDSRDVSRGEQPKYEDNLYMYLYFVIFIIFGSFFTLNLFIGVI 1416
Score = 81.4 bits (192), Expect = 2e-13
Identities = 38/104 (36%), Positives = 67/104 (64%), Gaps = 5/104 (4%)
Query: 724 EIIEQAGRQSRASELNVSVYYFPTAEDDEDGPTFKEKLLDCLMKGIDFFCVWDCCWLWLE 783
+ +++ G + RA ++V+ T E+ E+ ++K C + + +WDCC LWL+
Sbjct: 604 DYLDEPGARQRA--MSVASNLTNTMEELEES---RQKCPPCWYRFANTCLIWDCCPLWLK 658
Query: 784 FQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKAL 827
++ V+++V DPFV+L IT+CIV+NTLFMA++H+ M ++ D L
Sbjct: 659 IKEVVSMVVMDPFVDLTITICIVLNTLFMAMEHYPMTEEFDNVL 702
Score = 74.1 bits (174), Expect = 3e-11
Identities = 42/124 (33%), Positives = 72/124 (58%), Gaps = 11/124 (8%)
Query: 1259 FTVIFFIEMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKT 1314
FT I+ E LIK LA GF + + W WLDF +++++ +V G + A
Sbjct: 33 FTGIYTFESLIKILARGFCVGKFTFLRDPWNWLDFSVILMA---YVTEFVDLGNVSA--- 86
Query: 1315 MRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY- 1373
+RT R LR L+ +S + G++ +V AL+Q++ + +V+++ + +FA++G+QLF G
Sbjct: 87 LRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLR 146
Query: 1374 FKCV 1377
KCV
Sbjct: 147 QKCV 150
Score = 72.9 bits (171), Expect = 8e-11
Identities = 46/174 (26%), Positives = 85/174 (48%), Gaps = 11/174 (6%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W ++ ++ + + + + I+L++L +A+E H P ++L +FT IF
Sbjct: 656 WLKIKEVVSMVVMDPFVDLTITICIVLNTLFMAME--HYPMTEEFDNVL----SVFTGIF 709
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRP 1323
EM +K +AL YF W D IIV +SL+ G ++ +R+ R LR
Sbjct: 710 TAEMCLKIIALHPYYYFQEGWNIFDGIIVSLSLMEL-----GLANVEGLSVLRSFRLLRV 764
Query: 1324 LRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCV 1377
+ + +++ + ++ ++ N+ LV I IFA++G+QLF Y +CV
Sbjct: 765 FKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECV 818
Score = 53.6 bits (123), Expect = 5e-05
Identities = 41/156 (26%), Positives = 77/156 (49%), Gaps = 20/156 (12%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL-----RY 1592
F M+IM I N MTL + + ++ ++Y F I++ E L+KI A ++
Sbjct: 2 FSMLIMFTILTNCAFMTLSNPPE---WAKNVEYT---FTGIYTFESLIKILARGFCVGKF 55
Query: 1593 HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIR 1652
+ +PWN DF V++ + ++ FV + +R +V R L+ + G++
Sbjct: 56 TFLRDPWNWLDFSVILMAYVT---------EFVDLGNVSALRTFRVLRALKTISVIPGLK 106
Query: 1653 TLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
T++ AL S+ L ++ +L + +FA+ G+ FM
Sbjct: 107 TIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFM 142
Score = 41.5 bits (93), Expect = 0.23
Identities = 37/169 (21%), Positives = 77/169 (45%), Gaps = 21/169 (12%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVEST-------EVIFTGIYT 178
P N + + F + I+ I +N + M++ T E V+F ++T
Sbjct: 1472 PTNAFQGCVFDCITKQAFDIVIMILICLNMVTMMVETDDQTEEMGNILYWINVVFIVLFT 1531
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM---------GIDLGNLAALRT 229
E +K+++ L+ + Y WN DFVV+ L+ + M + L +R
Sbjct: 1532 GECLLKMIS----LRHY-YFTIGWNVFDFVVVILSIMGMFLSEVIEKYFVSPTLLRVIRL 1586
Query: 230 FRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGL 278
R+ R L+ + G++T++ A++ S+ L ++ +L + ++A+ G+
Sbjct: 1587 ARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGM 1635
Score = 41.1 bits (92), Expect = 0.30
Identities = 31/146 (21%), Positives = 68/146 (46%), Gaps = 7/146 (4%)
Query: 776 DCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRV 835
+C + + Y + ++ F + + L I+ L ++ + + + + ++ R+
Sbjct: 1533 ECLLKMISLRHYYFTIGWNVFDFVVVILSIMGMFLSEVIEKYFVSPTLLRVIRLARIGRI 1592
Query: 836 FKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDG 895
+L K + L+ + ++ AL N+ +L +++FI+A+ GM F YV R G
Sbjct: 1593 LRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFA-----YVKR-ESG 1646
Query: 896 DLPRWNFTDFMHSFMIVFRV-LCGEW 920
+NF F +S + +F++ G W
Sbjct: 1647 IDDMFNFETFGNSMICLFQITTSGGW 1672
>UniRef50_Q4SNV9 Cluster: Chromosome 15 SCAF14542, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 15 SCAF14542, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1860
Score = 822 bits (2033), Expect = 0.0
Identities = 403/754 (53%), Positives = 543/754 (72%), Gaps = 20/754 (2%)
Query: 1177 PADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALA 1236
P +C PE C + D Q W LR ++++E+++FET +I MILLSS ALA
Sbjct: 1065 PEECFPEFCVRHCQCCNIDVTHGLGQAWWRLRKTCYQIVEHSWFETFIIFMILLSSGALA 1124
Query: 1237 LEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSL 1296
ED+++ R +++ +L D++F+ IF +EM +KW+A GF+KYFTN WCWLDF+IV VSL
Sbjct: 1125 FEDIYIEKRKVIKVVLEAADKVFSYIFVLEMFLKWIAYGFKKYFTNYWCWLDFLIVDVSL 1184
Query: 1297 INFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLI 1356
I+ VA G A K++RTLRALRPLRA+SR +GMRVVVNAL+ AIPSI NVLLVCLI
Sbjct: 1185 ISLVANSLGYSDFTAIKSLRTLRALRPLRALSRFEGMRVVVNALIGAIPSIMNVLLVCLI 1244
Query: 1357 FWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYT---WENSPMNFDHVG 1413
FWLIF+IMGV LFAGK+ KCV+ + ++ +K+ C N T W +NFD+VG
Sbjct: 1245 FWLIFSIMGVNLFAGKFGKCVNRTGFIHTISVVNNKSDCLAMNDTQFYWTRVKVNFDNVG 1304
Query: 1414 KAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFI 1473
YL L QVATFKGW++IM+ A+DSR V QP+RE N+YMYLY TLNLFI
Sbjct: 1305 IGYLSLLQVATFKGWMEIMHAAVDSRGVEEQPVREINLYMYLYFVVFIIFGSFFTLNLFI 1364
Query: 1474 GVIIDNFNEQKKKAG---------GSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWR 1524
GVIIDNFN+QK+K G G ++FMTE+QKKYYNAMKK+GSKKP K IPRP
Sbjct: 1365 GVIIDNFNQQKRKMGLAAHLGGGPGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPTNI 1424
Query: 1525 PQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECL 1584
QA F++V+ + FD++IM+ I +NM+TM ++ +QSE A+L+ +N++FIVIF++EC+
Sbjct: 1425 IQAFFFDLVSKQAFDIMIMMLIIINMVTMMVETDEQSERTEAILNKINLVFIVIFTTECV 1484
Query: 1585 LKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRL 1644
+KIFALR ++F WN+FDFVV++ SI+ +VL+DIIEKYFVSPTL RV+R+A++GRVLRL
Sbjct: 1485 IKIFALRCYFFTIAWNIFDFVVIILSIVGIVLADIIEKYFVSPTLFRVIRLARIGRVLRL 1544
Query: 1645 VKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKT 1704
++ AKGIRTLLFAL MS+PALFNI LLLFLVMFI+AIFGM+ F +VK + G+DD++NF+T
Sbjct: 1545 IRAAKGIRTLLFALMMSMPALFNIGLLLFLVMFIYAIFGMANFAYVKKQDGIDDMFNFET 1604
Query: 1705 FVQSMILLFQMSTSAGWDGVLDGII--NEEECDLPDNERG--SPGNCGSATIGITYLLSY 1760
F SMI LFQ+STSAGWD +L I+ + EECD+ G + GNCGS ++GI + +SY
Sbjct: 1605 FGNSMICLFQISTSAGWDYLLSPIMANSPEECDVRFVNTGTNTRGNCGSPSVGIAFFVSY 1664
Query: 1761 LVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLS 1820
++ISFLIV+NMYIA+ILEN+S ATE+ E L++DD++M+YE+W++FD + +Q+I + LS
Sbjct: 1665 IIISFLIVVNMYIAIILENFSVATEESTEPLSEDDFEMFYEVWEKFDFEATQFIEFSMLS 1724
Query: 1821 DFLDVLEPPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTKDFFARKGNPIEETGDL 1880
+F D L PL+I KPN K+ISMD+P+ GD + C+DIL A TK G +
Sbjct: 1725 NFADTLSEPLRIAKPNMIKLISMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALKQQM 1784
Query: 1881 E----VGRPEEAGYEPVSSTLWRQREEYCARLIQ 1910
E + P + +EP++STL R+ EE A +IQ
Sbjct: 1785 EEKFMMTNPSKVSHEPITSTLRRKVEEVSATIIQ 1818
Score = 298 bits (731), Expect = 1e-78
Identities = 155/303 (51%), Positives = 205/303 (67%), Gaps = 15/303 (4%)
Query: 17 RPFTRESLXXXXXXXXXXXXKQKELEKKRAEGEVRYXXXXXXXGPQPDATLEQGLPLPVR 76
R FTRESL +++ E++ + ++ + +P LE G LP R
Sbjct: 14 RRFTRESLAAL---------ERRIAEERAKKAKICHNTHKNTDPLKPRVDLEAGKQLP-R 63
Query: 77 MQGSFPLELASTPLEDIDPFYH-NQTTFVVISKGKDIFRFSATNALWILDPFNPIRRVAI 135
+ G P EL PLED+DPFY+ NQ TF+V++KGK IFRFSAT+AL+I PF+ +R +A+
Sbjct: 64 IYGDVPPELIGIPLEDMDPFYYKNQRTFIVLNKGKSIFRFSATSALYIFSPFHFLRAIAV 123
Query: 136 YILVHPLFSLFIITTILVNCILMIMPT-TPTVESTEVIFTGIYTFESAVKVMARGFILQP 194
+LVH LFSLFI+ TIL NC M M P + E FT IYTFES +K+ ARGF + P
Sbjct: 124 RVLVHSLFSLFIMFTILTNCFFMAMSDPAPWTKYLEYTFTAIYTFESVIKIFARGFCVVP 183
Query: 195 FTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIE 254
F++LRD WNWLDF VI +AYVT +DLGN++ALRTFRVLRALKT++++PGLKTIVGA+I+
Sbjct: 184 FSFLRDPWNWLDFTVIVMAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQ 243
Query: 255 SVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNE 314
SV+ L DV+ILT+F LSVFAL+GLQ++MG+L QKCV+ G N + + E F N
Sbjct: 244 SVRKLADVMILTVFCLSVFALIGLQLFMGLLRQKCVRSL---GHCINSSYSSSESFVCNN 300
Query: 315 TNW 317
W
Sbjct: 301 RTW 303
Score = 154 bits (374), Expect = 2e-35
Identities = 72/101 (71%), Positives = 82/101 (81%), Gaps = 1/101 (0%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+S LRVFKLAKSWPTLN LI I+G ++GALGNLT VL II+FIFAV+GMQLFGKNY
Sbjct: 807 LRSFRLLRVFKLAKSWPTLNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKNYQ 866
Query: 887 DYVDRFP-DGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWD 926
D V + D LPRW+ DF HSF+IVFRVLCGEWIE+MWD
Sbjct: 867 DCVCKISFDCQLPRWHMKDFFHSFLIVFRVLCGEWIETMWD 907
Score = 126 bits (304), Expect = 6e-27
Identities = 64/105 (60%), Positives = 75/105 (71%), Gaps = 14/105 (13%)
Query: 316 NWYGEGG--DYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQ 373
N+Y G D +CG S AG+C G+ CL+ G NPNYGYTSFDTFGWAFL+ FRLMTQ
Sbjct: 341 NFYKTEGAKDALICGYGSDAGKCPDGFDCLK-VGRNPNYGYTSFDTFGWAFLALFRLMTQ 399
Query: 374 DYWENL-----------YQLFFVVIIFLGSFYLVNLILAIVAMSY 407
DYWE L Y +FFV++IFLGSFYLVNLILA+VAM+Y
Sbjct: 400 DYWEKLFHQTLRSAGKTYMVFFVLVIFLGSFYLVNLILAVVAMAY 444
Score = 108 bits (259), Expect = 2e-21
Identities = 83/256 (32%), Positives = 135/256 (52%), Gaps = 21/256 (8%)
Query: 1521 PRWRP-QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIF 1579
P WR + V +V D D+ I + I LN L M L+HY +E F+ +L N++F IF
Sbjct: 701 PWWRQIKEWVKRMVMDPFLDLGITICIVLNTLFMALEHYPMTEEFNTMLSVGNLVFTGIF 760
Query: 1580 SSECLLKIFAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKV 1638
++E +LK+ AL Y+YF + WN+FD V+V S++ L LS++ L V+R ++
Sbjct: 761 TAEMVLKLIALDPYYYFQQGWNIFDGVIVCLSLMELGLSNV--------EGLSVLRSFRL 812
Query: 1639 GRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF-MHVKD---KG 1694
RV +L K + TL+ + S+ AL N+ L+L +++FIFA+ GM F + +D K
Sbjct: 813 LRVFKLAKSWPTLNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKNYQDCVCKI 872
Query: 1695 GLD---DVYNFKTFVQSMILLFQMSTSAGWDGVLDGI---INEEECDLPDNERGSPGNCG 1748
D ++ K F S +++F++ + + D + + + PD E G N
Sbjct: 873 SFDCQLPRWHMKDFFHSFLIVFRVLCGEWIETMWDWLWSSFSSDNLSAPD-EDGDLNNIQ 931
Query: 1749 SATIGITYLLSYLVIS 1764
A IT +S+LV S
Sbjct: 932 IAIARITTGVSWLVSS 947
Score = 79.4 bits (187), Expect = 9e-13
Identities = 51/187 (27%), Positives = 96/187 (51%), Gaps = 14/187 (7%)
Query: 113 FRFSATNALWILDPF-NPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTE- 170
+ F+ +W P+ I+ +++ P L I I++N + M + P E
Sbjct: 688 YTFAKKYLIWECCPWWRQIKEWVKRMVMDPFLDLGITICIVLNTLFMALEHYPMTEEFNT 747
Query: 171 ------VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGN 223
++FTGI+T E +K++A L P+ Y + WN D V++ L+ + +G+ ++
Sbjct: 748 MLSVGNLVFTGIFTAEMVLKLIA----LDPYYYFQQGWNIFDGVIVCLSLMELGLSNVEG 803
Query: 224 LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
L+ LR+FR+LR K P L T++ + SV L ++ ++ + +FA++G+Q++ G
Sbjct: 804 LSVLRSFRLLRVFKLAKSWPTLNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLF-G 862
Query: 284 VLTQKCV 290
Q CV
Sbjct: 863 KNYQDCV 869
Score = 78.6 bits (185), Expect = 2e-12
Identities = 46/174 (26%), Positives = 85/174 (48%), Gaps = 7/174 (4%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W ++ +++ + + + + I+L++L +ALE H P +L + +FT IF
Sbjct: 703 WRQIKEWVKRMVMDPFLDLGITICIVLNTLFMALE--HYPMTEEFNTMLSVGNLVFTGIF 760
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRP 1323
EM++K +AL YF W D +IV +SL+ G ++ +R+ R LR
Sbjct: 761 TAEMVLKLIALDPYYYFQQGWNIFDGVIVCLSLMEL-----GLSNVEGLSVLRSFRLLRV 815
Query: 1324 LRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCV 1377
+ + ++ + ++ ++ N+ LV I IFA++G+QLF Y CV
Sbjct: 816 FKLAKSWPTLNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKNYQDCV 869
Score = 77.4 bits (182), Expect = 4e-12
Identities = 47/157 (29%), Positives = 83/157 (52%), Gaps = 14/157 (8%)
Query: 1254 YMDRIFTVIFFIEMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGI 1309
Y++ FT I+ E +IK A GF + + W WLDF +++++ +V G +
Sbjct: 157 YLEYTFTAIYTFESVIKIFARGFCVVPFSFLRDPWNWLDFTVIVMA---YVTEFVDLGNV 213
Query: 1310 QAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
A +RT R LR L+ +S + G++ +V AL+Q++ + +V+++ + +FA++G+QLF
Sbjct: 214 SA---LRTFRVLRALKTISVIPGLKTIVGALIQSVRKLADVMILTVFCLSVFALIGLQLF 270
Query: 1370 AGKY-FKCV-DMNHTTLSHEIIPDKNACTLENYTWEN 1404
G KCV + H S + C N TW +
Sbjct: 271 MGLLRQKCVRSLGHCINSSYSSSESFVC--NNRTWSS 305
Score = 72.1 bits (169), Expect = 1e-10
Identities = 29/74 (39%), Positives = 48/74 (64%)
Query: 758 KEKLLDCLMKGIDFFCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHH 817
++K C + +W+CC W + +++V +V DPF++L IT+CIV+NTLFMAL+H+
Sbjct: 680 RQKCHPCWYTFAKKYLIWECCPWWRQIKEWVKRMVMDPFLDLGITICIVLNTLFMALEHY 739
Query: 818 NMDKDMDKALKSGN 831
M ++ + L GN
Sbjct: 740 PMTEEFNTMLSVGN 753
Score = 69.7 bits (163), Expect = 7e-10
Identities = 70/293 (23%), Positives = 135/293 (46%), Gaps = 39/293 (13%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMPTT---------PTVESTEVIFTGIYTFE 180
+R+ I+ H F FII IL++ + +E+ + +F+ I+ E
Sbjct: 1095 LRKTCYQIVEHSWFETFIIFMILLSSGALAFEDIYIEKRKVIKVVLEAADKVFSYIFVLE 1154
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI------DLGNLAALRTFRVLR 234
+K +A GF Y + W WLDF+++ ++ +++ D + +LRT R LR
Sbjct: 1155 MFLKWIAYGFK----KYFTNYWCWLDFLIVDVSLISLVANSLGYSDFTAIKSLRTLRALR 1210
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFP 294
L+ ++ G++ +V A+I ++ ++ +V+++ + +F++MG+ ++ G KCV
Sbjct: 1211 PLRALSRFEGMRVVVNALIGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKF-GKCVN--- 1266
Query: 295 EDGSWGNLTDENWERFC--QNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNY 352
G ++ N + C N+T +Y + N G GY+ L
Sbjct: 1267 RTGFIHTISVVNNKSDCLAMNDTQFYWT----RVKVNFDNVG---IGYLSLLQVAT---- 1315
Query: 353 GYTSFDTFGWAFLSAFRLMTQDYWE-NLYQ-LFFVVIIFLGSFYLVNLILAIV 403
+ + A + + + Q E NLY L+FVV I GSF+ +NL + ++
Sbjct: 1316 -FKGWMEIMHAAVDSRGVEEQPVREINLYMYLYFVVFIIFGSFFTLNLFIGVI 1367
Score = 56.8 bits (131), Expect = 6e-06
Identities = 43/168 (25%), Positives = 78/168 (46%), Gaps = 20/168 (11%)
Query: 1526 QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLL 1585
+AI ++ F + IM I N M + + YL F I++ E ++
Sbjct: 119 RAIAVRVLVHSLFSLFIMFTILTNCFFMAMSDP------APWTKYLEYTFTAIYTFESVI 172
Query: 1586 KIFA-----LRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGR 1640
KIFA + + + +PWN DF V+ V++ + E FV + +R +V R
Sbjct: 173 KIFARGFCVVPFSFLRDPWNWLDFTVI-------VMAYVTE--FVDLGNVSALRTFRVLR 223
Query: 1641 VLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
L+ + G++T++ AL S+ L ++ +L + +FA+ G+ FM
Sbjct: 224 ALKTISVIPGLKTIVGALIQSVRKLADVMILTVFCLSVFALIGLQLFM 271
Score = 53.2 bits (122), Expect = 7e-05
Identities = 46/180 (25%), Positives = 87/180 (48%), Gaps = 25/180 (13%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTE-------VIFTGIYT 178
P N I+ ++ F + I+ I++N + M++ T E TE ++F I+T
Sbjct: 1421 PTNIIQAFFFDLVSKQAFDIMIMMLIIINMVTMMVETDEQSERTEAILNKINLVFIVIFT 1480
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNL-----------AAL 227
E +K+ F L+ + + AWN DFVVI L+ V GI L ++ +
Sbjct: 1481 TECVIKI----FALRCY-FFTIAWNIFDFVVIILSIV--GIVLADIIEKYFVSPTLFRVI 1533
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQ 287
R R+ R L+ + G++T++ A++ S+ L ++ +L + ++A+ G+ + V Q
Sbjct: 1534 RLARIGRVLRLIRAAKGIRTLLFALMMSMPALFNIGLLLFLVMFIYAIFGMANFAYVKKQ 1593
Score = 41.5 bits (93), Expect = 0.23
Identities = 31/129 (24%), Positives = 64/129 (49%), Gaps = 6/129 (4%)
Query: 787 YVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLN 846
Y + ++ F + I L IV L ++ + + + + ++ RV +L ++ +
Sbjct: 1493 YFFTIAWNIFDFVVIILSIVGIVLADIIEKYFVSPTLFRVIRLARIGRVLRLIRAAKGIR 1552
Query: 847 LLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFM 906
L+ + +M AL N+ +L +++FI+A+ GM F YV + DG +NF F
Sbjct: 1553 TLLFALMMSMPALFNIGLLLFLVMFIYAIFGMANFA-----YVKK-QDGIDDMFNFETFG 1606
Query: 907 HSFMIVFRV 915
+S + +F++
Sbjct: 1607 NSMICLFQI 1615
>UniRef50_UPI00015A61DE Cluster: sodium channel, voltage-gated, type
I, alpha; n=3; Danio rerio|Rep: sodium channel,
voltage-gated, type I, alpha - Danio rerio
Length = 1913
Score = 820 bits (2028), Expect = 0.0
Identities = 393/745 (52%), Positives = 536/745 (71%), Gaps = 12/745 (1%)
Query: 1177 PADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALA 1236
P C C ++F D++ W+ W LR + ++E+++FET ++ MILLSS ALA
Sbjct: 1082 PEPCFTAGCVRRFRCCQVDEEKGIWKKWWLLRQTCYNIVEHSWFETFIVFMILLSSGALA 1141
Query: 1237 LEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSL 1296
ED++L R ++ IL + D++FT IF +EML+KW+A GF KYFTN WCWLDF+IV VSL
Sbjct: 1142 FEDIYLDTRKSVKTILEFADKVFTYIFILEMLLKWVAYGFAKYFTNLWCWLDFVIVDVSL 1201
Query: 1297 INFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLI 1356
I+ VA + A K++RTLRA RPLRA+SR GMRVVVNAL+ AIPSI NVLLVCLI
Sbjct: 1202 ISLVANALNYSELSAIKSLRTLRAFRPLRALSRFDGMRVVVNALLGAIPSIMNVLLVCLI 1261
Query: 1357 FWLIFAIMGVQLFAGKYFKCVDMN-HTTLSHEIIPDKNACTL--ENYTWENSPMNFDHVG 1413
FWLIF+I+GV FAGK+ +C+++ L + +K C + W N +NFD+VG
Sbjct: 1262 FWLIFSIVGVNFFAGKFSECINITTEQRLPVSEVYNKTDCERMGKGVRWRNVIINFDNVG 1321
Query: 1414 KAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFI 1473
YL L QVATFKGW+ IM A+DSR QP E N+YMYLY TLNLFI
Sbjct: 1322 NGYLALLQVATFKGWMPIMYAAVDSRNPEEQPEYEVNLYMYLYFVIFIILGAFFTLNLFI 1381
Query: 1474 GVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIV 1533
GVIIDNFN+QKKK GG ++FMTE+QKKYYNAMKK+GSKKP K IPRP+ + Q ++F++V
Sbjct: 1382 GVIIDNFNQQKKKFGGQ-DIFMTEEQKKYYNAMKKLGSKKPQKPIPRPKNKIQGLIFDLV 1440
Query: 1534 TDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH 1593
T + FD+ IM+ I LNM+TM L+ QS + L ++N+IFIV+F++EC+LK+ ALR++
Sbjct: 1441 TKQAFDIFIMVLIWLNMVTMMLETEDQSIEMTRALYWINVIFIVLFTTECVLKMIALRHY 1500
Query: 1594 YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRT 1653
+F WN+FDF+VV+ SI+ + L+++I+KYFVSPTL RV+R+A++GRVLRL++ AKGIRT
Sbjct: 1501 FFTVGWNVFDFIVVILSIVGMSLTEVIKKYFVSPTLFRVIRLARIGRVLRLIRSAKGIRT 1560
Query: 1654 LLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLF 1713
LLFAL MSLPALFNI LLLFLVMFI+AIFGMS F +VK G+DD++NF+TF SM+ LF
Sbjct: 1561 LLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKKTAGIDDMFNFETFPNSMLCLF 1620
Query: 1714 QMSTSAGWDGVLDGIINEE--ECDLPDNERGSP--GNCGSATIGITYLLSYLVISFLIVI 1769
Q++TS GWDG+L ++N + +CD N GS G+CG+ +IGI + +SY++I FLIV+
Sbjct: 1621 QITTSGGWDGLLAPMLNSKPPDCDPTKNFTGSSVVGDCGNPSIGIFFFVSYIIICFLIVV 1680
Query: 1770 NMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPP 1829
NMYIAVILEN+S ATE+ E L++DD+D +YE+W++FDP +Q++ Y +LSDF D L+PP
Sbjct: 1681 NMYIAVILENFSVATEESAEPLSEDDFDRFYEVWEKFDPKATQFMEYGKLSDFADSLDPP 1740
Query: 1830 LQIHKPNKYKIISMDIPICRGDMMFCVDILDALTKDFFARKGNPIEETGDLE----VGRP 1885
L+I KPN+++++SMD+P+ GD + C+DIL A TK G G +E P
Sbjct: 1741 LRIPKPNRFQLMSMDLPMVTGDRIHCLDILFAFTKRVLGEGGEMDMLHGQMEDRFMQSNP 1800
Query: 1886 EEAGYEPVSSTLWRQREEYCARLIQ 1910
++ YEP+++TL R+ E+ A +IQ
Sbjct: 1801 SKSSYEPITTTLRRKHEDMSAAVIQ 1825
Score = 413 bits (1018), Expect = e-113
Identities = 222/411 (54%), Positives = 280/411 (68%), Gaps = 32/411 (7%)
Query: 17 RPFTRESLXXXXXXXXXXXXKQ-KELEKKRAEGEVRYXXXXXXXGPQPDATLEQGLPLPV 75
R FTRESL K+ K E++ + E +P++ LE G LP
Sbjct: 14 RKFTRESLKAIESRIAEENAKKSKNTEERNKDNEC---------SRKPNSGLEAGKTLPF 64
Query: 76 RMQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNALWILDPFNPIRRVAI 135
+ G P L STPLED+D FY N TTF+V+SK K+I+RF+AT AL+I FN +RR++I
Sbjct: 65 -IYGEVPKGLVSTPLEDLDQFYSNHTTFIVVSKKKEIYRFNATPALYIFSSFNLLRRISI 123
Query: 136 YILVHPLFSLF---IITTILVNCILMIMPTTPT-VESTEVIFTGIYTFESAVKVMARGFI 191
ILVH F+LF II TIL NC M+ TP +S E +FTGIYT E+ VK+ ARGF
Sbjct: 124 QILVHSSFTLFNFIIICTILANCAFMVYTQTPDWAKSVEYVFTGIYTLEALVKITARGFC 183
Query: 192 LQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGA 251
+ FT+LRD WNWLDF+VI +AYVT +DLG+++ALR FRVLRALKT+++VPGLKTIVGA
Sbjct: 184 VGRFTFLRDPWNWLDFIVIVMAYVTEFVDLGSVSALRAFRVLRALKTISVVPGLKTIVGA 243
Query: 252 VIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCV--KVFPEDGSWGNLTDENWER 309
+I+SVK L DV+ILT+F LSVFAL+GLQ++MG+L QKCV F E+ ++
Sbjct: 244 LIQSVKKLSDVMILTLFCLSVFALVGLQLFMGILKQKCVYSTSFTENKE-ACYKNKTCRD 302
Query: 310 FCQNETNWYGEGG--DYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSA 367
+ N +N Y G D +CGNSS AGQC GY CL+ G NP+YGYTSFD+FGWAFLS
Sbjct: 303 YINNPSNQYFLPGKKDALICGNSSDAGQCPEGYTCLKA-GNNPDYGYTSFDSFGWAFLSL 361
Query: 368 FRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
FRLMTQD+WENLYQ +FFV++IFLGSFYLVNLILA+VAM+Y
Sbjct: 362 FRLMTQDFWENLYQQTLRAAGKTYMIFFVLVIFLGSFYLVNLILAVVAMAY 412
Score = 163 bits (396), Expect = 4e-38
Identities = 94/220 (42%), Positives = 126/220 (57%), Gaps = 5/220 (2%)
Query: 786 KYVALLVFDPFVELF-ITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPT 844
K +AL + F+E + I I+V M L N+ + L+ LRVFKLAKSWPT
Sbjct: 756 KVIALDPYSYFLEGWNIFDSIIVTLSLMELCLANVLSGIG-FLRPFRLLRVFKLAKSWPT 814
Query: 845 LNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF-PDGDLPRWNFT 903
LN+LI I+G ++GAL NLT VL II+FIFAV+GMQLFGK+Y + V + D LPRW+
Sbjct: 815 LNMLIKIIGNSLGALSNLTLVLAIIVFIFAVVGMQLFGKSYGECVCKISSDCMLPRWHMN 874
Query: 904 DFMHSFMIVFRVLCGEWIESMWDCM-LVGDVSCIPFFLATVVIXXXXXXXXXXXXXXXXX 962
DF HSF+IVFRVLCGEWIE+MWDCM + G C+ F+ +VI
Sbjct: 875 DFFHSFLIVFRVLCGEWIETMWDCMEVAGQPLCLTVFMMVMVIGNLVVLNLFLALLLSSF 934
Query: 963 XXXXXXTPTADQDTNKIAEAFNRISRFIDWIKRNVADFLK 1002
+ ++D N + A RI + +IK + F +
Sbjct: 935 SADNLAV-SGEEDENNLQIAVRRIRKGFTFIKTCLQSFFR 973
Score = 100 bits (240), Expect = 3e-19
Identities = 56/169 (33%), Positives = 97/169 (57%), Gaps = 9/169 (5%)
Query: 1521 PRW-RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIF 1579
P W R + +V IV D D+ I + I +N + M ++ Y +S++L N++FI IF
Sbjct: 690 PTWLRIKEVVHMIVMDPFADLFITICIVINTVFMAMECYPMDGPYSSMLSTANVVFIGIF 749
Query: 1580 SSECLLKIFAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKV 1638
++E + K+ AL Y YF+E WN+FD ++V S++ L L++++ + +R ++
Sbjct: 750 TAEMIFKVIALDPYSYFLEGWNIFDSIIVTLSLMELCLANVLSG-------IGFLRPFRL 802
Query: 1639 GRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
RV +L K + L+ + SL AL N+ L+L +++FIFA+ GM F
Sbjct: 803 LRVFKLAKSWPTLNMLIKIIGNSLGALSNLTLVLAIIVFIFAVVGMQLF 851
Score = 79.8 bits (188), Expect = 7e-13
Identities = 51/188 (27%), Positives = 94/188 (50%), Gaps = 15/188 (7%)
Query: 113 FRFSATNALWILDP-FNPIRRVAIYILVHPLFSLFIITTILVNCILMIM-------PTTP 164
F F+ +W P + I+ V I++ P LFI I++N + M M P +
Sbjct: 677 FEFAENYLIWDCSPTWLRIKEVVHMIVMDPFADLFITICIVINTVFMAMECYPMDGPYSS 736
Query: 165 TVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID--LG 222
+ + V+F GI+T E KV+A L P++Y + WN D +++ L+ + + + L
Sbjct: 737 MLSTANVVFIGIFTAEMIFKVIA----LDPYSYFLEGWNIFDSIIVTLSLMELCLANVLS 792
Query: 223 NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYM 282
+ LR FR+LR K P L ++ + S+ L ++ ++ + +FA++G+Q++
Sbjct: 793 GIGFLRPFRLLRVFKLAKSWPTLNMLIKIIGNSLGALSNLTLVLAIIVFIFAVVGMQLF- 851
Query: 283 GVLTQKCV 290
G +CV
Sbjct: 852 GKSYGECV 859
Score = 75.4 bits (177), Expect = 2e-11
Identities = 44/146 (30%), Positives = 79/146 (54%), Gaps = 11/146 (7%)
Query: 1255 MDRIFTVIFFIEMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQ 1310
++ +FT I+ +E L+K A GF + + W WLDFI+++++ +V G +
Sbjct: 161 VEYVFTGIYTLEALVKITARGFCVGRFTFLRDPWNWLDFIVIVMA---YVTEFVDLGSVS 217
Query: 1311 AFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
A +R R LR L+ +S + G++ +V AL+Q++ + +V+++ L +FA++G+QLF
Sbjct: 218 A---LRAFRVLRALKTISVVPGLKTIVGALIQSVKKLSDVMILTLFCLSVFALVGLQLFM 274
Query: 1371 G-KYFKCVDMNHTTLSHEIIPDKNAC 1395
G KCV T + E C
Sbjct: 275 GILKQKCVYSTSFTENKEACYKNKTC 300
Score = 71.7 bits (168), Expect = 2e-10
Identities = 66/292 (22%), Positives = 139/292 (47%), Gaps = 37/292 (12%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMI-----MPTTPTV----ESTEVIFTGIYTFE 180
+R+ I+ H F FI+ IL++ + + T +V E + +FT I+ E
Sbjct: 1112 LRQTCYNIVEHSWFETFIVFMILLSSGALAFEDIYLDTRKSVKTILEFADKVFTYIFILE 1171
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI------DLGNLAALRTFRVLR 234
+K +A GF Y + W WLDFV++ ++ +++ +L + +LRT R R
Sbjct: 1172 MLLKWVAYGFA----KYFTNLWCWLDFVIVDVSLISLVANALNYSELSAIKSLRTLRAFR 1227
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFP 294
L+ ++ G++ +V A++ ++ ++ +V+++ + +F+++G+ + G ++ C+ +
Sbjct: 1228 PLRALSRFDGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIVGVNFFAGKFSE-CINITT 1286
Query: 295 EDGSWGNLTDENWERFCQNETNWYGEGGDY-PLCGNSSGAGQCEPGYVCLQGFGPNPNYG 353
E L E + + + G+G + + N G GY+ L
Sbjct: 1287 EQ----RLPVS--EVYNKTDCERMGKGVRWRNVIINFDNVGN---GYLALLQVAT----- 1332
Query: 354 YTSFDTFGWAFLSAFRLMTQ-DYWENLYQ-LFFVVIIFLGSFYLVNLILAIV 403
+ + +A + + Q +Y NLY L+FV+ I LG+F+ +NL + ++
Sbjct: 1333 FKGWMPIMYAAVDSRNPEEQPEYEVNLYMYLYFVIFIILGAFFTLNLFIGVI 1384
Score = 70.1 bits (164), Expect = 6e-10
Identities = 39/115 (33%), Positives = 63/115 (54%), Gaps = 4/115 (3%)
Query: 718 DVMVLNEIIEQAGRQS-RASELNVSVYYFPTAEDDEDGPTFKEKLLDCLMKGIDFFCVWD 776
D ++ +A RQS R L+V+ AE E FK++ + + + + +WD
Sbjct: 631 DSIIFVSNFSKAYRQSMRERALSVASGSNNPAECSE---IFKQRCEEWWFEFAENYLIWD 687
Query: 777 CCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGN 831
C WL ++ V ++V DPF +LFIT+CIV+NT+FMA++ + MD L + N
Sbjct: 688 CSPTWLRIKEVVHMIVMDPFADLFITICIVINTVFMAMECYPMDGPYSSMLSTAN 742
Score = 68.5 bits (160), Expect = 2e-09
Identities = 75/296 (25%), Positives = 132/296 (44%), Gaps = 41/296 (13%)
Query: 1196 DDSPFWQGWGTLRLK--TFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILY 1253
D SP W LR+K ++ + + + + I+++++ +A+E P +L
Sbjct: 687 DCSPTW-----LRIKEVVHMIVMDPFADLFITICIVINTVFMAMECY--PMDGPYSSMLS 739
Query: 1254 YMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFK 1313
+ +F IF EM+ K +AL YF W D IIV +SL+ LC A +
Sbjct: 740 TANVVFIGIFTAEMIFKVIALDPYSYFLEGWNIFDSIIVTLSLME----LCLANVLSGIG 795
Query: 1314 TMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
+R R LR + + +++ + ++ ++ N+ LV I IFA++G+QLF Y
Sbjct: 796 FLRPFRLLRVFKLAKSWPTLNMLIKIIGNSLGALSNLTLVLAIIVFIFAVVGMQLFGKSY 855
Query: 1374 FKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMN 1433
+CV +S + C L W + +F H ++L +F+V + WI+ M
Sbjct: 856 GECV----CKISSD-------CMLPR--WHMN--DFFH---SFLIVFRVLCGE-WIETMW 896
Query: 1434 DAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGG 1489
D + EV QP+ T M + LNLF+ +++ +F+ G
Sbjct: 897 DCM---EVAGQPLCLTVFMMVM------VIGNLVVLNLFLALLLSSFSADNLAVSG 943
Score = 57.6 bits (133), Expect = 3e-06
Identities = 41/168 (24%), Positives = 81/168 (48%), Gaps = 17/168 (10%)
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKI 1587
I +I+ F + + I + Y Q+ ++ ++Y +F I++ E L+KI
Sbjct: 121 ISIQILVHSSFTLFNFIIICTILANCAFMVYTQTPDWAKSVEY---VFTGIYTLEALVKI 177
Query: 1588 FAL-----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVL 1642
A R+ + +PWN DF+V+ V++ + E FV + +R +V R L
Sbjct: 178 TARGFCVGRFTFLRDPWNWLDFIVI-------VMAYVTE--FVDLGSVSALRAFRVLRAL 228
Query: 1643 RLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHV 1690
+ + G++T++ AL S+ L ++ +L + +FA+ G+ FM +
Sbjct: 229 KTISVVPGLKTIVGALIQSVKKLSDVMILTLFCLSVFALVGLQLFMGI 276
Score = 50.0 bits (114), Expect = 6e-04
Identities = 40/169 (23%), Positives = 83/169 (49%), Gaps = 21/169 (12%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTP-TVESTE------VIFTGIYT 178
P N I+ + ++ F +FI+ I +N + M++ T ++E T VIF ++T
Sbjct: 1428 PKNKIQGLIFDLVTKQAFDIFIMVLIWLNMVTMMLETEDQSIEMTRALYWINVIFIVLFT 1487
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMG---------IDLGNLAALRT 229
E +K++A L+ + + WN DF+V+ L+ V M + +R
Sbjct: 1488 TECVLKMIA----LRHY-FFTVGWNVFDFIVVILSIVGMSLTEVIKKYFVSPTLFRVIRL 1542
Query: 230 FRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGL 278
R+ R L+ + G++T++ A++ S+ L ++ +L + ++A+ G+
Sbjct: 1543 ARIGRVLRLIRSAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGM 1591
Score = 42.7 bits (96), Expect = 0.098
Identities = 32/146 (21%), Positives = 69/146 (47%), Gaps = 7/146 (4%)
Query: 776 DCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRV 835
+C + + Y + ++ F + + L IV +L + + + + + ++ RV
Sbjct: 1489 ECVLKMIALRHYFFTVGWNVFDFIVVILSIVGMSLTEVIKKYFVSPTLFRVIRLARIGRV 1548
Query: 836 FKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDG 895
+L +S + L+ + ++ AL N+ +L +++FI+A+ GM F YV +
Sbjct: 1549 LRLIRSAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFA-----YVKKTAGI 1603
Query: 896 DLPRWNFTDFMHSFMIVFRV-LCGEW 920
D +NF F +S + +F++ G W
Sbjct: 1604 D-DMFNFETFPNSMLCLFQITTSGGW 1628
>UniRef50_P35498 Cluster: Sodium channel protein type 1 subunit alpha;
n=169; Euteleostomi|Rep: Sodium channel protein type 1
subunit alpha - Homo sapiens (Human)
Length = 2009
Score = 819 bits (2027), Expect = 0.0
Identities = 401/750 (53%), Positives = 540/750 (72%), Gaps = 19/750 (2%)
Query: 1177 PADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALA 1236
P C E C Q+F + + + W LR F+++E+ +FET ++ MILLSS ALA
Sbjct: 1177 PEACFTEGCVQRFKCCQINVEEGRGKQWWNLRRTCFRIVEHNWFETFIVFMILLSSGALA 1236
Query: 1237 LEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSL 1296
ED+++ R ++ +L Y D++FT IF +EML+KW+A G+Q YFTNAWCWLDF+IV VSL
Sbjct: 1237 FEDIYIDQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGYQTYFTNAWCWLDFLIVDVSL 1296
Query: 1297 INFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLI 1356
++ A G + A K++RTLRALRPLRA+SR +GMRVVVNAL+ AIPSI NVLLVCLI
Sbjct: 1297 VSLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLI 1356
Query: 1357 FWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACT--------LENYTWENSPMN 1408
FWLIF+IMGV LFAGK++ C+ N TT I D N T E W+N +N
Sbjct: 1357 FWLIFSIMGVNLFAGKFYHCI--NTTTGDRFDIEDVNNHTDCLKLIERNETARWKNVKVN 1414
Query: 1409 FDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXT 1468
FD+VG YL L QVATFKGW+ IM A+DSR V QP E ++YMYLY T
Sbjct: 1415 FDNVGFGYLSLLQVATFKGWMDIMYAAVDSRNVELQPKYEESLYMYLYFVIFIIFGSFFT 1474
Query: 1469 LNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAI 1528
LNLFIGVIIDNFN+QKKK GG ++FMTE+QKKYYNAMKK+GSKKP K IPRP + Q +
Sbjct: 1475 LNLFIGVIIDNFNQQKKKFGGQ-DIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKFQGM 1533
Query: 1529 VFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIF 1588
VF+ VT + FD+ IM+ I LNM+TM ++ QSE + +L +N++FIV+F+ EC+LK+
Sbjct: 1534 VFDFVTRQVFDISIMILICLNMVTMMVETDDQSEYVTTILSRINLVFIVLFTGECVLKLI 1593
Query: 1589 ALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGA 1648
+LR++YF WN+FDFVVV+ SI+ + L+++IEKYFVSPTL RV+R+A++GR+LRL+KGA
Sbjct: 1594 SLRHYYFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRLARIGRILRLIKGA 1653
Query: 1649 KGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQS 1708
KGIRTLLFAL MSLPALFNI LLLFLVMFI+AIFGMS F +VK + G+DD++NF+TF S
Sbjct: 1654 KGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNS 1713
Query: 1709 MILLFQMSTSAGWDGVLDGIINEE--ECDLPDNERGS--PGNCGSATIGITYLLSYLVIS 1764
MI LFQ++TSAGWDG+L I+N + +CD GS G+CG+ ++GI + +SY++IS
Sbjct: 1714 MICLFQITTSAGWDGLLAPILNSKPPDCDPNKVNPGSSVKGDCGNPSVGIFFFVSYIIIS 1773
Query: 1765 FLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLD 1824
FL+V+NMYIAVILEN+S ATE+ E L++DD++M+YE+W++FDPD +Q++ +++LS F
Sbjct: 1774 FLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFMEFEKLSQFAA 1833
Query: 1825 VLEPPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTKDFFARKGN----PIEETGDL 1880
LEPPL + +PNK ++I+MD+P+ GD + C+DIL A TK G I+
Sbjct: 1834 ALEPPLNLPQPNKLQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRIQMEERF 1893
Query: 1881 EVGRPEEAGYEPVSSTLWRQREEYCARLIQ 1910
P + Y+P+++TL R++EE A +IQ
Sbjct: 1894 MASNPSKVSYQPITTTLKRKQEEVSAVIIQ 1923
Score = 431 bits (1063), Expect = e-119
Identities = 229/425 (53%), Positives = 289/425 (68%), Gaps = 45/425 (10%)
Query: 16 FRPFTRESLXXXXXXXXXXXXKQKELEKKRAEGEVRYXXXXXXXGPQPDATLEQGLPLPV 75
F FTRESL K + +KK + GP+P++ LE G LP
Sbjct: 14 FNFFTRESLAAIERRIAEEKAKNPKPDKKDDDEN----------GPKPNSDLEAGKNLPF 63
Query: 76 RMQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNALWILDPFNPIRRVAI 135
+ G P E+ S PLED+DP+Y N+ TF+V++KGK IFRFSAT+AL+IL PFNP+R++AI
Sbjct: 64 -IYGDIPPEMVSEPLEDLDPYYINKKTFIVLNKGKAIFRFSATSALYILTPFNPLRKIAI 122
Query: 136 YILVHPLFSLFIITTILVNCILMIMPTTPT-VESTEVIFTGIYTFESAVKVMARGFILQP 194
ILVH LFS+ I+ TIL NC+ M M P ++ E FTGIYTFES +K++ARGF L+
Sbjct: 123 KILVHSLFSMLIMCTILTNCVFMTMSNPPDWTKNVEYTFTGIYTFESLIKIIARGFCLED 182
Query: 195 FTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIE 254
FT+LRD WNWLDF VI AYVT +DLGN++ALRTFRVLRALKT++++PGLKTIVGA+I+
Sbjct: 183 FTFLRDPWNWLDFTVITFAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQ 242
Query: 255 SVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSW--------------G 300
SVK L DV+ILT+F LSVFAL+GLQ++MG L KC++ P + S G
Sbjct: 243 SVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCIQWPPTNASLEEHSIEKNITVNYNG 302
Query: 301 NLTDE-----NWERFCQNETNWYGEGG--DYPLCGNSSGAGQCEPGYVCLQGFGPNPNYG 353
L +E +W+ + Q+ Y G D LCGNSS AGQC GY+C++ G NPNYG
Sbjct: 303 TLINETVFEFDWKSYIQDSRYHYFLEGFLDALLCGNSSDAGQCPEGYMCVKA-GRNPNYG 361
Query: 354 YTSFDTFGWAFLSAFRLMTQDYWENLYQL-----------FFVVIIFLGSFYLVNLILAI 402
YTSFDTF WAFLS FRLMTQD+WENLYQL FFV++IFLGSFYL+NLILA+
Sbjct: 362 YTSFDTFSWAFLSLFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAV 421
Query: 403 VAMSY 407
VAM+Y
Sbjct: 422 VAMAY 426
Score = 179 bits (436), Expect = 6e-43
Identities = 88/191 (46%), Positives = 120/191 (62%), Gaps = 5/191 (2%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+S LRVFKLAKSWPTLN+LI I+G ++GALGNLT VL II+FIFAV+GMQLFGK+Y
Sbjct: 858 LRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYK 917
Query: 887 DYVDRF-PDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCM-LVGDVSCIPFFLATVV 944
D V + D LPRW+ DF HSF+IVFRVLCGEWIE+MWDCM + G C+ F+ +V
Sbjct: 918 DCVCKIASDCQLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLTVFMMVMV 977
Query: 945 IXXXXXXXXXXXXXXXXXXXXXXXTPTADQDTNKIAEAFNRISRFIDWIKRNVADFLK-- 1002
I D + N + A +R+ + + ++KR + +F++
Sbjct: 978 IGNLVVLNLFLALLLSSFSADNLAATDDDNEMNNLQIAVDRMHKGVAYVKRKIYEFIQQS 1037
Query: 1003 -LLKNKLTNQI 1012
+ K K+ ++I
Sbjct: 1038 FIRKQKILDEI 1048
Score = 101 bits (241), Expect = 3e-19
Identities = 87/287 (30%), Positives = 147/287 (51%), Gaps = 38/287 (13%)
Query: 1521 PRW-RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIF 1579
P W + + +V +V D D+ I + I LN L M ++HY ++ F+ VL N++F IF
Sbjct: 752 PYWLKVKHVVNLVVMDPFVDLAITICIVLNTLFMAMEHYPMTDHFNNVLTVGNLVFTGIF 811
Query: 1580 SSECLLKIFAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKV 1638
++E LKI A+ Y+YF E WN+FD +V S++ L L+++ L V+R ++
Sbjct: 812 TAEMFLKIIAMDPYYYFQEGWNIFDGFIVTLSLVELGLANV--------EGLSVLRSFRL 863
Query: 1639 GRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF-MHVKD---KG 1694
RV +L K + L+ + S+ AL N+ L+L +++FIFA+ GM F KD K
Sbjct: 864 LRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKDCVCKI 923
Query: 1695 GLD---DVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSAT 1751
D ++ F S +++F+ VL G E D E C
Sbjct: 924 ASDCQLPRWHMNDFFHSFLIVFR---------VLCGEWIETMWDC--MEVAGQAMC---- 968
Query: 1752 IGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDM 1798
+T + +VI L+V+N+++A++L ++S +++ TDDD +M
Sbjct: 969 --LTVFMMVMVIGNLVVLNLFLALLLSSFS--ADNL--AATDDDNEM 1009
Score = 80.6 bits (190), Expect = 4e-13
Identities = 55/199 (27%), Positives = 97/199 (48%), Gaps = 14/199 (7%)
Query: 1181 CPEQCYQKFP--FLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALE 1238
CP C+ KF FL D SP+W ++ ++ + + + A+ I+L++L +A+E
Sbjct: 734 CPP-CWYKFSNIFLIWDC-SPYWL---KVKHVVNLVVMDPFVDLAITICIVLNTLFMAME 788
Query: 1239 DVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLIN 1298
H P ++L + +FT IF EM +K +A+ YF W D IV +SL+
Sbjct: 789 --HYPMTDHFNNVLTVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVTLSLVE 846
Query: 1299 FVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFW 1358
G ++ +R+ R LR + + +++ + ++ ++ N+ LV I
Sbjct: 847 L-----GLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIV 901
Query: 1359 LIFAIMGVQLFAGKYFKCV 1377
IFA++G+QLF Y CV
Sbjct: 902 FIFAVVGMQLFGKSYKDCV 920
Score = 80.6 bits (190), Expect = 4e-13
Identities = 49/187 (26%), Positives = 97/187 (51%), Gaps = 14/187 (7%)
Query: 113 FRFSATNALWILDPF-NPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTE- 170
++FS +W P+ ++ V +++ P L I I++N + M M P +
Sbjct: 739 YKFSNIFLIWDCSPYWLKVKHVVNLVVMDPFVDLAITICIVLNTLFMAMEHYPMTDHFNN 798
Query: 171 ------VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGN 223
++FTGI+T E +K++A + P+ Y ++ WN D ++ L+ V +G+ ++
Sbjct: 799 VLTVGNLVFTGIFTAEMFLKIIA----MDPYYYFQEGWNIFDGFIVTLSLVELGLANVEG 854
Query: 224 LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
L+ LR+FR+LR K P L ++ + SV L ++ ++ + +FA++G+Q++ G
Sbjct: 855 LSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLF-G 913
Query: 284 VLTQKCV 290
+ CV
Sbjct: 914 KSYKDCV 920
Score = 80.2 bits (189), Expect = 5e-13
Identities = 72/292 (24%), Positives = 137/292 (46%), Gaps = 34/292 (11%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMP--------TTPTV-ESTEVIFTGIYTFE 180
+RR I+ H F FI+ IL++ + T T+ E + +FT I+ E
Sbjct: 1207 LRRTCFRIVEHNWFETFIVFMILLSSGALAFEDIYIDQRKTIKTMLEYADKVFTYIFILE 1266
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI------DLGNLAALRTFRVLR 234
+K +A G+ TY +AW WLDF+++ ++ V++ +LG + +LRT R LR
Sbjct: 1267 MLLKWVAYGYQ----TYFTNAWCWLDFLIVDVSLVSLTANALGYSELGAIKSLRTLRALR 1322
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFP 294
L+ ++ G++ +V A++ ++ ++ +V+++ + +F++MG+ ++ G C+
Sbjct: 1323 PLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKF-YHCINT-- 1379
Query: 295 EDGSWGNLTDENWERFCQN--ETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNY 352
G ++ D N C E N + + ++ G GY+ L +
Sbjct: 1380 TTGDRFDIEDVNNHTDCLKLIERNETARWKNVKVNFDNVGF-----GYLSLLQVATFKGW 1434
Query: 353 GYTSFDTFGWAFLSAFRLMTQDYWENLYQ-LFFVVIIFLGSFYLVNLILAIV 403
D A S + Y E+LY L+FV+ I GSF+ +NL + ++
Sbjct: 1435 ----MDIMYAAVDSRNVELQPKYEESLYMYLYFVIFIIFGSFFTLNLFIGVI 1482
Score = 78.6 bits (185), Expect = 2e-12
Identities = 43/135 (31%), Positives = 72/135 (53%), Gaps = 5/135 (3%)
Query: 697 KPSSDNPFIESSQQPNVVDMRDVMVLNEIIEQAGRQSRASELNVSVYYFPTAEDDEDGPT 756
KP++D+ + + V + +E ++ RA ++++ T E+ E+
Sbjct: 675 KPATDDNGTTTETEMRKRRSSSFHVSMDFLEDPSQRQRA--MSIASILTNTVEELEES-- 730
Query: 757 FKEKLLDCLMKGIDFFCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDH 816
++K C K + F +WDC WL+ + V L+V DPFV+L IT+CIV+NTLFMA++H
Sbjct: 731 -RQKCPPCWYKFSNIFLIWDCSPYWLKVKHVVNLVVMDPFVDLAITICIVLNTLFMAMEH 789
Query: 817 HNMDKDMDKALKSGN 831
+ M + L GN
Sbjct: 790 YPMTDHFNNVLTVGN 804
Score = 75.4 bits (177), Expect = 2e-11
Identities = 51/165 (30%), Positives = 86/165 (52%), Gaps = 13/165 (7%)
Query: 1259 FTVIFFIEMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKT 1314
FT I+ E LIK +A GF + + W WLDF ++ + +V G + A
Sbjct: 161 FTGIYTFESLIKIIARGFCLEDFTFLRDPWNWLDFTVITFA---YVTEFVDLGNVSA--- 214
Query: 1315 MRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY- 1373
+RT R LR L+ +S + G++ +V AL+Q++ + +V+++ + +FA++G+QLF G
Sbjct: 215 LRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLR 274
Query: 1374 FKCVDMNHTTLS-HEIIPDKNACTLENYTWENSPMNFDHVGKAYL 1417
KC+ T S E +KN N T N + F+ K+Y+
Sbjct: 275 NKCIQWPPTNASLEEHSIEKNITVNYNGTLINETV-FEFDWKSYI 318
Score = 56.4 bits (130), Expect = 7e-06
Identities = 45/166 (27%), Positives = 81/166 (48%), Gaps = 20/166 (12%)
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKI 1587
I +I+ F M+IM I N + MT+ + ++ ++Y F I++ E L+KI
Sbjct: 120 IAIKILVHSLFSMLIMCTILTNCVFMTMSN---PPDWTKNVEYT---FTGIYTFESLIKI 173
Query: 1588 ----FALRYHYFV-EPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVL 1642
F L F+ +PWN DF V+ F+ ++ FV + +R +V R L
Sbjct: 174 IARGFCLEDFTFLRDPWNWLDFTVITFAYVT---------EFVDLGNVSALRTFRVLRAL 224
Query: 1643 RLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
+ + G++T++ AL S+ L ++ +L + +FA+ G+ FM
Sbjct: 225 KTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFM 270
Score = 41.9 bits (94), Expect = 0.17
Identities = 36/169 (21%), Positives = 79/169 (46%), Gaps = 21/169 (12%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT-------TPTVESTEVIFTGIYT 178
P N + + + +F + I+ I +N + M++ T T + ++F ++T
Sbjct: 1526 PGNKFQGMVFDFVTRQVFDISIMILICLNMVTMMVETDDQSEYVTTILSRINLVFIVLFT 1585
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM---------GIDLGNLAALRT 229
E +K+++ L+ + Y WN DFVV+ L+ V M + +R
Sbjct: 1586 GECVLKLIS----LRHY-YFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRL 1640
Query: 230 FRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGL 278
R+ R L+ + G++T++ A++ S+ L ++ +L + ++A+ G+
Sbjct: 1641 ARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGM 1689
Score = 39.9 bits (89), Expect = 0.69
Identities = 30/140 (21%), Positives = 66/140 (47%), Gaps = 6/140 (4%)
Query: 776 DCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRV 835
+C + + Y + ++ F + + L IV L ++ + + + + ++ R+
Sbjct: 1587 ECVLKLISLRHYYFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRLARIGRI 1646
Query: 836 FKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDG 895
+L K + L+ + ++ AL N+ +L +++FI+A+ GM F YV R
Sbjct: 1647 LRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFA-----YVKREVGI 1701
Query: 896 DLPRWNFTDFMHSFMIVFRV 915
D +NF F +S + +F++
Sbjct: 1702 D-DMFNFETFGNSMICLFQI 1720
>UniRef50_UPI0000ECCD59 Cluster: Voltage-gated sodium channel SNS;
n=3; Gallus gallus|Rep: Voltage-gated sodium channel SNS
- Gallus gallus
Length = 1760
Score = 808 bits (1999), Expect = 0.0
Identities = 395/746 (52%), Positives = 533/746 (71%), Gaps = 17/746 (2%)
Query: 1176 TPADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLAL 1235
TP C E C + F G + + W LR ++++E+++FE+ ++ MILLSS L
Sbjct: 970 TPEKCFSEGCVRYFHCCKGRAVNFGGKTWWNLRKTCYQIVEHSWFESFIVFMILLSSGVL 1029
Query: 1236 ALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVS 1295
A ED+H+ R ++ IL ++DR+FT +FF+EM++KW+A GF KYFTNAWCWLDF+IV VS
Sbjct: 1030 AFEDIHINERRTIKAILSFLDRLFTFVFFLEMILKWVAYGFNKYFTNAWCWLDFLIVGVS 1089
Query: 1296 LINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCL 1355
LIN + + + K++RTLRALRPLRA+SR +GMRVVVNALV AIPSI NVLLVCL
Sbjct: 1090 LINILGS-----SLDGVKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCL 1144
Query: 1356 IFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEI-IPDKNACTLENYT----WENSPMNFD 1410
IFWLIF+IMGV LFAGK+ KCV++ + I D C N+T W N +NFD
Sbjct: 1145 IFWLIFSIMGVNLFAGKFGKCVNLTEENSELDSSINDIADCKAWNHTGKIFWVNVKVNFD 1204
Query: 1411 HVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLN 1470
+VG YL L QVATFKGW++IM A+DSRE QP E N++MYLY TLN
Sbjct: 1205 NVGSGYLALLQVATFKGWMEIMYAAVDSREKDEQPKMEYNLFMYLYFVNFIIFGSFFTLN 1264
Query: 1471 LFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVF 1530
LF+GVIIDNFN+QKKK GG ++FMTE+QKKYYNAMK++GSKKP K IPRP R Q +F
Sbjct: 1265 LFVGVIIDNFNQQKKKLGGE-DIFMTEEQKKYYNAMKRLGSKKPQKPIPRPLNRYQGFLF 1323
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL 1590
+IVT++ FD+ IM+ I LNM+TM ++ Y+QS+ + VL+ +N++F+ IFS+EC+LK+ AL
Sbjct: 1324 DIVTNQAFDITIMILICLNMVTMMVETYEQSDMKTNVLNKINILFVTIFSTECVLKLVAL 1383
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIE--KYFVSPTLLRVVRVAKVGRVLRLVKGA 1648
R +YF WN+FD VVV+ SI++L+LS I + ++F+ PTL RV+R+A++GR+LRL++ A
Sbjct: 1384 RQYYFSNAWNIFDIVVVIMSIVALLLSGIGKAFEHFLPPTLFRVIRLARIGRILRLIRAA 1443
Query: 1649 KGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQS 1708
KGIRTLLFAL MSLPALFNI LLLFLVMFI+AIFGM+ F +VK + G+DD++NF+TF S
Sbjct: 1444 KGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMANFAYVKMEDGIDDMFNFQTFANS 1503
Query: 1709 MILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIV 1768
M+ LF+++TSAGWDG+L I+N N GS G CG IGI Y +SY++ISFLIV
Sbjct: 1504 MLCLFEITTSAGWDGLLSPILNTGPPYCDPNITGSIGECGKPAIGIVYFVSYIIISFLIV 1563
Query: 1769 INMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEP 1828
+NMYIAVILEN++ ATE+ E L +DD+D++YEIW++FDP+ +Q+I + LSDF D L
Sbjct: 1564 VNMYIAVILENFNAATEESTEPLGEDDFDIFYEIWEKFDPEATQFITFSALSDFADALAE 1623
Query: 1829 PLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTKDFFARKGN----PIEETGDLEVGR 1884
PL++ KPNK ++I+MD+P+ GD + C+DIL A TK G ++
Sbjct: 1624 PLRVPKPNKIELIAMDLPMVSGDRIHCLDILFAFTKRVLGDSGEMDVLKVQMEDKFMAVN 1683
Query: 1885 PEEAGYEPVSSTLWRQREEYCARLIQ 1910
P + YEP+S+TL ++EE A +IQ
Sbjct: 1684 PSKKSYEPISTTLRHRQEEVSATVIQ 1709
Score = 367 bits (902), Expect = 2e-99
Identities = 209/429 (48%), Positives = 263/429 (61%), Gaps = 50/429 (11%)
Query: 16 FRPFTRESLXXXXXXXXXXXXKQKELEKKRAEGEVRYXXXXXXXGPQPDATLEQGLPLPV 75
FR FT ESL QK ++ E + R PQ D Q LP
Sbjct: 12 FRKFTPESLAAIEKRIAAKKDHQKSTLDQKPEEKPR---------PQLDLKAFQKLPA-- 60
Query: 76 RMQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNALWILDPFNPIRRVAI 135
+ G+ P EL PLED+DP+Y ++ F+V++K K IFRF+AT ALWIL PF+PIRR AI
Sbjct: 61 -LYGNPPPELIGEPLEDLDPYYKDRKIFIVLNKQKTIFRFTATRALWILSPFHPIRRAAI 119
Query: 136 YILVHPLFSLFIITTILVNCILMIMPTTPTVES------TEVIFTGIYTFESAVKVMARG 189
I +H LF+ FII TI+ NC+ M + S E FTGIYTFES +K++ARG
Sbjct: 120 KISIHSLFTWFIICTIITNCVFMAQNESSRSSSPSWNRYVEFTFTGIYTFESLIKILARG 179
Query: 190 FILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIV 249
F L FT+LRD WNWLDF VI +A+V +LG+++ LRTFRVLRALKT+++VPGLK IV
Sbjct: 180 FCLNEFTFLRDPWNWLDFSVIIMAFVGAFSNLGSVSVLRTFRVLRALKTISVVPGLKIIV 239
Query: 250 GAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGN---LTDEN 306
GA+I+SVK L +V+ILT+F LSVFAL+GLQ++ G L KCVK D + + +
Sbjct: 240 GALIQSVKKLANVMILTVFCLSVFALIGLQLFKGNLRYKCVKKNHTDSTIRDFLLMLSSA 299
Query: 307 WER----------FCQNETNWYGE-------GGDYPLCGNSSGAGQCEPGYVCLQGFGPN 349
W R F + GE D LCG +G+ C P + C Q GPN
Sbjct: 300 WNRGISLKVKITFFFIAYIPYIGEHFAIKPGTSDVLLCGPGAGSRTCPPEHTCKQ-IGPN 358
Query: 350 PNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNL 398
P+YG+TSFDTFGWAFLS FRLMTQDYWE LYQ LFF+++IFLGSFYLVNL
Sbjct: 359 PDYGFTSFDTFGWAFLSLFRLMTQDYWERLYQQTLRASGKVYILFFMLVIFLGSFYLVNL 418
Query: 399 ILAIVAMSY 407
ILA+V M+Y
Sbjct: 419 ILAVVTMAY 427
Score = 161 bits (392), Expect = 1e-37
Identities = 81/202 (40%), Positives = 118/202 (58%), Gaps = 6/202 (2%)
Query: 799 LFITLCIVVNTLFMALDHHNMDKDMDKA-----LKSGNYLRVFKLAKSWPTLNLLISIMG 853
+F ++ + ++ + ++L K+ K L+S LRVFKLAKSWPTLN LI I+G
Sbjct: 662 IFDSIIVTLSLIELSLPRQRGKKERRKGGTLSVLRSFRLLRVFKLAKSWPTLNTLIKIIG 721
Query: 854 RTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMIVF 913
++GAL NLT VL II+FIFA++G+QLFG +Y Y D+ RW+ DF HSF+++F
Sbjct: 722 NSLGALSNLTLVLAIIVFIFAIVGVQLFGGSYRTYGDKIKKNGEIRWHMMDFFHSFLVIF 781
Query: 914 RVLCGEWIESMWDCMLVGDVS-CIPFFLATVVIXXXXXXXXXXXXXXXXXXXXXXXTPTA 972
R+LCGEWIE+MWDCM+V + C+ FL +VI T
Sbjct: 782 RILCGEWIETMWDCMVVAEKPLCLLVFLLVMVIGNLVVLNLFIALLLNSFSTDCLQTAED 841
Query: 973 DQDTNKIAEAFNRISRFIDWIK 994
D++ N + AF RI + + ++K
Sbjct: 842 DREMNNLRIAFARIHKGLRFVK 863
Score = 99.1 bits (236), Expect = 1e-18
Identities = 81/282 (28%), Positives = 140/282 (49%), Gaps = 30/282 (10%)
Query: 1521 PRW-RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIF 1579
P W R + V + D D+ I L I +N L M L+H +E F +L N++ +
Sbjct: 580 PLWLRIKKKVAAFIKDPFIDLTITLCIVMNTLFMALEHNNMTENFKLMLKVGNLVKSTLE 639
Query: 1580 SSECLLKIFALR-YHYFVEPWNLFDFVVVMFSILSLVLS-DIIEKYFVSPTLLRVVRVAK 1637
++E +LKI AL Y+YF +PWN+FD ++V S++ L L +K L V+R +
Sbjct: 640 TAEMVLKIIALDPYYYFQQPWNIFDSIIVTLSLIELSLPRQRGKKERRKGGTLSVLRSFR 699
Query: 1638 VGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF------MHVK 1691
+ RV +L K + TL+ + SL AL N+ L+L +++FIFAI G+ F K
Sbjct: 700 LLRVFKLAKSWPTLNTLIKIIGNSLGALSNLTLVLAIIVFIFAIVGVQLFGGSYRTYGDK 759
Query: 1692 DKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSAT 1751
K + ++ F S +++F++ + + D ++ E+
Sbjct: 760 IKKNGEIRWHMMDFFHSFLVIFRILCGEWIETMWDCMVVAEK-----------------P 802
Query: 1752 IGITYLLSYLVISFLIVINMYIAVILENYS----QATEDVQE 1789
+ + L +VI L+V+N++IA++L ++S Q ED +E
Sbjct: 803 LCLLVFLLVMVIGNLVVLNLFIALLLNSFSTDCLQTAEDDRE 844
Score = 91.1 bits (216), Expect = 3e-16
Identities = 55/181 (30%), Positives = 97/181 (53%), Gaps = 14/181 (7%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+R K+ ++ F +I I+ + + +A + P Y++ FT I+ E
Sbjct: 114 IRRAAIKISIHSLFTWFIICTIITNCVFMAQNESSRSSSPSWNR---YVEFTFTGIYTFE 170
Query: 1267 MLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALR 1322
LIK LA GF + + W WLDF +++++ FV A G + +T R LRAL+
Sbjct: 171 SLIKILARGFCLNEFTFLRDPWNWLDFSVIIMA---FVGAFSNLGSVSVLRTFRVLRALK 227
Query: 1323 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKCVDMNH 1381
+ S + G++++V AL+Q++ + NV+++ + +FA++G+QLF G +KCV NH
Sbjct: 228 TI---SVVPGLKIIVGALIQSVKKLANVMILTVFCLSVFALIGLQLFKGNLRYKCVKKNH 284
Query: 1382 T 1382
T
Sbjct: 285 T 285
Score = 83.8 bits (198), Expect = 4e-14
Identities = 51/138 (36%), Positives = 73/138 (52%), Gaps = 10/138 (7%)
Query: 702 NPFIESSQQPNVVDMRDVMVLN-----EIIEQAGRQSRASELNVSVYYFPTAEDDEDGPT 756
N QQP V D +M L+ E + ++ RA+ VS+ E +E
Sbjct: 503 NTITSCRQQPAVNDESSMMHLHPQLSVEYFNETFQRQRAASA-VSIITSVLEELEESQQK 561
Query: 757 FKEKLLDCLMKGIDFFCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDH 816
L D K + +W+CC LWL +K VA + DPF++L ITLCIV+NTLFMAL+H
Sbjct: 562 CPRFLKDFAFK----YLIWNCCPLWLRIKKKVAAFIKDPFIDLTITLCIVMNTLFMALEH 617
Query: 817 HNMDKDMDKALKSGNYLR 834
+NM ++ LK GN ++
Sbjct: 618 NNMTENFKLMLKVGNLVK 635
Score = 77.0 bits (181), Expect = 5e-12
Identities = 66/286 (23%), Positives = 134/286 (46%), Gaps = 28/286 (9%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEV---------IFTGIYTFE 180
+R+ I+ H F FI+ IL++ ++ E + +FT ++ E
Sbjct: 1001 LRKTCYQIVEHSWFESFIVFMILLSSGVLAFEDIHINERRTIKAILSFLDRLFTFVFFLE 1060
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVT-MGIDLGNLAALRTFRVLRALKTV 239
+K +A GF Y +AW WLDF+++ ++ + +G L + +LRT R LR L+ +
Sbjct: 1061 MILKWVAYGFN----KYFTNAWCWLDFLIVGVSLINILGSSLDGVKSLRTLRALRPLRAL 1116
Query: 240 AIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSW 299
+ G++ +V A++ ++ ++ +V+++ + +F++MG+ ++ G KCV + E+
Sbjct: 1117 SRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKF-GKCVNLTEENSEL 1175
Query: 300 GNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDT 359
+ ++ + N T G+ + N G GY+ L + +
Sbjct: 1176 DSSINDIADCKAWNHT---GKIFWVNVKVNFDNVGS---GYLALLQVAT-----FKGWME 1224
Query: 360 FGWAFLSAFRLMTQDYWE-NLYQ-LFFVVIIFLGSFYLVNLILAIV 403
+A + + Q E NL+ L+FV I GSF+ +NL + ++
Sbjct: 1225 IMYAAVDSREKDEQPKMEYNLFMYLYFVNFIIFGSFFTLNLFVGVI 1270
Score = 62.5 bits (145), Expect = 1e-07
Identities = 47/174 (27%), Positives = 85/174 (48%), Gaps = 6/174 (3%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W ++ K I++ + + + I++++L +ALE ++ L +L + + + +
Sbjct: 582 WLRIKKKVAAFIKDPFIDLTITLCIVMNTLFMALEHNNMTENFKL--MLKVGNLVKSTLE 639
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINF-VAALCGAGGIQAFKTMRTLRALR 1322
EM++K +AL YF W D IIV +SLI + G + T+ LR+ R
Sbjct: 640 TAEMVLKIIALDPYYYFQQPWNIFDSIIVTLSLIELSLPRQRGKKERRKGGTLSVLRSFR 699
Query: 1323 PLRAMSRMQG---MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
LR + + ++ + ++ ++ N+ LV I IFAI+GVQLF G Y
Sbjct: 700 LLRVFKLAKSWPTLNTLIKIIGNSLGALSNLTLVLAIIVFIFAIVGVQLFGGSY 753
Score = 57.2 bits (132), Expect = 4e-06
Identities = 40/170 (23%), Positives = 83/170 (48%), Gaps = 22/170 (12%)
Query: 131 RRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVIF-------TGIYTFESAV 183
++VA +I P L I I++N + M + E+ +++ + + T E +
Sbjct: 587 KKVAAFIK-DPFIDLTITLCIVMNTLFMALEHNNMTENFKLMLKVGNLVKSTLETAEMVL 645
Query: 184 KVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDL----------GNLAALRTFRVL 233
K++A L P+ Y + WN D +++ L+ + + + G L+ LR+FR+L
Sbjct: 646 KIIA----LDPYYYFQQPWNIFDSIIVTLSLIELSLPRQRGKKERRKGGTLSVLRSFRLL 701
Query: 234 RALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
R K P L T++ + S+ L ++ ++ + +FA++G+Q++ G
Sbjct: 702 RVFKLAKSWPTLNTLIKIIGNSLGALSNLTLVLAIIVFIFAIVGVQLFGG 751
Score = 52.0 bits (119), Expect = 2e-04
Identities = 40/158 (25%), Positives = 71/158 (44%), Gaps = 19/158 (12%)
Query: 1570 YLNMIFIVIFSSECLLKIFAL-----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYF 1624
Y+ F I++ E L+KI A + + +PWN DF V++ + + F
Sbjct: 158 YVEFTFTGIYTFESLIKILARGFCLNEFTFLRDPWNWLDFSVIIMAFVGA---------F 208
Query: 1625 VSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGM 1684
+ + V+R +V R L+ + G++ ++ AL S+ L N+ +L + +FA+ G+
Sbjct: 209 SNLGSVSVLRTFRVLRALKTISVVPGLKIIVGALIQSVKKLANVMILTVFCLSVFALIGL 268
Query: 1685 SFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWD 1722
F KG L K S I F + S+ W+
Sbjct: 269 QLF-----KGNLRYKCVKKNHTDSTIRDFLLMLSSAWN 301
Score = 46.4 bits (105), Expect = 0.008
Identities = 37/171 (21%), Positives = 82/171 (47%), Gaps = 23/171 (13%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT-------TPTVESTEVIFTGIYT 178
P N + I+ + F + I+ I +N + M++ T T + ++F I++
Sbjct: 1314 PLNRYQGFLFDIVTNQAFDITIMILICLNMVTMMVETYEQSDMKTNVLNKINILFVTIFS 1373
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID-LGN----------LAAL 227
E +K++A L+ + Y +AWN D VV+ ++ V + + +G +
Sbjct: 1374 TECVLKLVA----LRQY-YFSNAWNIFDIVVVIMSIVALLLSGIGKAFEHFLPPTLFRVI 1428
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGL 278
R R+ R L+ + G++T++ A++ S+ L ++ +L + ++A+ G+
Sbjct: 1429 RLARIGRILRLIRAAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGM 1479
Score = 42.7 bits (96), Expect = 0.098
Identities = 27/124 (21%), Positives = 63/124 (50%), Gaps = 7/124 (5%)
Query: 792 VFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISI 851
+FD V + + ++++ + A +H + + + ++ R+ +L ++ + L+
Sbjct: 1394 IFDIVVVIMSIVALLLSGIGKAFEHF-LPPTLFRVIRLARIGRILRLIRAAKGIRTLLFA 1452
Query: 852 MGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMI 911
+ ++ AL N+ +L +++FI+A+ GM F YV + DG +NF F +S +
Sbjct: 1453 LMMSLPALFNIGLLLFLVMFIYAIFGMANFA--YV----KMEDGIDDMFNFQTFANSMLC 1506
Query: 912 VFRV 915
+F +
Sbjct: 1507 LFEI 1510
>UniRef50_Q9Y5Y9 Cluster: Sodium channel protein type 10 subunit
alpha; n=31; cellular organisms|Rep: Sodium channel
protein type 10 subunit alpha - Homo sapiens (Human)
Length = 1956
Score = 802 bits (1984), Expect = 0.0
Identities = 394/754 (52%), Positives = 534/754 (70%), Gaps = 21/754 (2%)
Query: 1175 DTPADCCPEQCYQKFPFLAGDDDSPFWQ-GWGTLRLKTFKLIENTYFETAVITMILLSSL 1233
+ P DC E C + P D W GW +R ++++E+++FE+ +I MILLSS
Sbjct: 1109 EEPDDCFTEGCIRHCPCCKLDTTKSPWDVGW-QVRKTCYRIVEHSWFESFIIFMILLSSG 1167
Query: 1234 ALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVM 1293
+LA ED +L +P ++ +L Y DR+FT IF EML+KW+A GF+KYFTNAWCWLDF+IV
Sbjct: 1168 SLAFEDYYLDQKPTVKALLEYTDRVFTFIFVFEMLLKWVAYGFKKYFTNAWCWLDFLIVN 1227
Query: 1294 VSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLV 1353
+SLI+ A + + K +RTLRALRPLRA+SR +GMRVVV+ALV AIPSI NVLLV
Sbjct: 1228 ISLISLTAKILEYSEVAPIKALRTLRALRPLRALSRFEGMRVVVDALVGAIPSIMNVLLV 1287
Query: 1354 CLIFWLIFAIMGVQLFAGKYFKCV---DMNHTTLSHEIIPDKNACTLENYT----WENSP 1406
CLIFWLIF+IMGV LFAGK+++C+ D + + I+ +K+ C ++N T W N
Sbjct: 1288 CLIFWLIFSIMGVNLFAGKFWRCINYTDGEFSLVPLSIVNNKSDCKIQNSTGSFFWVNVK 1347
Query: 1407 MNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXX 1466
+NFD+V YL L QVATFKGW+ IM A+DSREV QP E N+YMYLY
Sbjct: 1348 VNFDNVAMGYLALLQVATFKGWMDIMYAAVDSREVNMQPKWEDNVYMYLYFVIFIIFGGF 1407
Query: 1467 XTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQ 1526
TLNLF+GVIIDNFN+QKKK GG ++FMTE+QKKYYNAMKK+GSKKP K IPRP + Q
Sbjct: 1408 FTLNLFVGVIIDNFNQQKKKLGGQ-DIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKFQ 1466
Query: 1527 AIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLK 1586
VF+IVT + FD+ IM+ I LNM+TM ++ QSE + +L +N F+ +F+ EC++K
Sbjct: 1467 GFVFDIVTRQAFDITIMVLICLNMITMMVETDDQSEEKTKILGKINQFFVAVFTGECVMK 1526
Query: 1587 IFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIE--KYFVSPTLLRVVRVAKVGRVLRL 1644
+FALR +YF WN+FDF+VV+ SI SL+ S I++ + + SPTL RV+R+A++GR+LRL
Sbjct: 1527 MFALRQYYFTNGWNVFDFIVVVLSIASLIFSAILKSLQSYFSPTLFRVIRLARIGRILRL 1586
Query: 1645 VKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKT 1704
++ AKGIRTLLFAL MSLPALFNI LLLFLVMFI++IFGMS F HV+ + G+DD++NF+T
Sbjct: 1587 IRAAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMSSFPHVRWEAGIDDMFNFQT 1646
Query: 1705 FVQSMILLFQMSTSAGWDGVLDGIIN--EEECD--LPDNERGSPGNCGSATIGITYLLSY 1760
F SM+ LFQ++TSAGWDG+L I+N CD LP N G+ G+CGS +GI + +Y
Sbjct: 1647 FANSMLCLFQITTSAGWDGLLSPILNTGPPYCDPNLP-NSNGTRGDCGSPAVGIIFFTTY 1705
Query: 1761 LVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLS 1820
++ISFLIV+NMYIAVILEN++ ATE+ E L++DD+DM+YE W++FDP+ +Q+I + LS
Sbjct: 1706 IIISFLIVVNMYIAVILENFNVATEESTEPLSEDDFDMFYETWEKFDPEATQFITFSALS 1765
Query: 1821 DFLDVLEPPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTKDFFARKGNPIEETGDL 1880
DF D L PL+I KPN+ +I MD+P+ GD + C+DIL A TK+ G ++
Sbjct: 1766 DFADTLSGPLRIPKPNRNILIQMDLPLVPGDKIHCLDILFAFTKNVLGESGELDSLKANM 1825
Query: 1881 E----VGRPEEAGYEPVSSTLWRQREEYCARLIQ 1910
E ++ YEP+++TL ++E+ A +IQ
Sbjct: 1826 EEKFMATNLSKSSYEPIATTLRWKQEDISATVIQ 1859
Score = 386 bits (949), Expect = e-105
Identities = 212/411 (51%), Positives = 256/411 (62%), Gaps = 26/411 (6%)
Query: 8 ISEEERSLFRPFTRESLXXXXXXXXXXXXKQKELEKKRAEGEVRYXXXXXXXGPQPDATL 67
I E + FR FT ESL +K EK R + + P+P L
Sbjct: 5 IGSLETNNFRRFTPESLVEIEKQIAAKQGTKKAREKHREQKDQEEK-------PRPQLDL 57
Query: 68 EQGLPLPVRMQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNALWILDPF 127
+ LP + G P EL PLED+DPFY TF+V++KG+ I RFSAT ALW+ PF
Sbjct: 58 KACNQLP-KFYGELPAELIGEPLEDLDPFYSTHRTFMVLNKGRTISRFSATRALWLFSPF 116
Query: 128 NPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMA 187
N IRR AI + VH FSLFI TILVNC+ M P E E +FT IYTFE+ +K++A
Sbjct: 117 NLIRRTAIKVSVHSWFSLFITVTILVNCVCMTRTDLP--EKIEYVFTVIYTFEALIKILA 174
Query: 188 RGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKT 247
RGF L FTYLRD WNWLDF VI LAYV IDL ++ LRTFRVLRALKTV+++PGLK
Sbjct: 175 RGFCLNEFTYLRDPWNWLDFSVITLAYVGTAIDLRGISGLRTFRVLRALKTVSVIPGLKV 234
Query: 248 IVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENW 307
IVGA+I SVK L DV ILT+F LSVFAL+GLQ++ G L KCVK D + T+ +
Sbjct: 235 IVGALIHSVKKLADVTILTIFCLSVFALVGLQLFKGNLKNKCVK---NDMAVNETTNYSS 291
Query: 308 ERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSA 367
R N G D LCGN S +G C GY+CL+ NP++ YTSFD+F WAFLS
Sbjct: 292 HRKPDIYINKRGT-SDPLLCGNGSDSGHCPDGYICLK-TSDNPDFNYTSFDSFAWAFLSL 349
Query: 368 FRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
FRLMTQD WE LYQ +FFV++IFLGSFYLVNLILA+V M+Y
Sbjct: 350 FRLMTQDSWERLYQQTLRTSGKIYMIFFVLVIFLGSFYLVNLILAVVTMAY 400
Score = 159 bits (385), Expect = 9e-37
Identities = 89/218 (40%), Positives = 117/218 (53%), Gaps = 9/218 (4%)
Query: 790 LLVFDPFV----ELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTL 845
++ FDP+ + I CI+V + L K L+S LRVFKLAKSWPTL
Sbjct: 716 IIAFDPYYYFQKKWNIFDCIIVTVSLLELGVAK--KGSLSVLRSFRLLRVFKLAKSWPTL 773
Query: 846 NLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF--PDGDLPRWNFT 903
N LI I+G ++GALGNLT +L II+F+FA++G QL G+NY + P D PRW+
Sbjct: 774 NTLIKIIGNSVGALGNLTIILAIIVFVFALVGKQLLGENYRNNRKNISAPHEDWPRWHMH 833
Query: 904 DFMHSFMIVFRVLCGEWIESMWDCMLVGDVS-CIPFFLATVVIXXXXXXXXXXXXXXXXX 962
DF HSF+IVFR+LCGEWIE+MW CM VG S C+ FL +V+
Sbjct: 834 DFFHSFLIVFRILCGEWIENMWACMEVGQKSICLILFLTVMVLGNLVVLNLFIALLLNSF 893
Query: 963 XXXXXXTPTADQDTNKIAEAFNRISRFIDWIKRNVADF 1000
P D + N + A RI F K+ + F
Sbjct: 894 SADNLTAPEDDGEVNNLQVALARIQVFGHRTKQALCSF 931
Score = 97.5 bits (232), Expect = 3e-18
Identities = 55/165 (33%), Positives = 98/165 (59%), Gaps = 10/165 (6%)
Query: 1521 PRW-RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIF 1579
P W + + I+F +VTD ++ I L I +N + M ++H+ S TF A+L N++F + F
Sbjct: 649 PMWVKLKTILFGLVTDPFAELTITLCIVVNTIFMAMEHHGMSPTFEAMLQIGNIVFTIFF 708
Query: 1580 SSECLLKIFAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKV 1638
++E + KI A Y+YF + WN+FD ++V S+L L + +K +S V+R ++
Sbjct: 709 TAEMVFKIIAFDPYYYFQKKWNIFDCIIVTVSLLEL---GVAKKGSLS-----VLRSFRL 760
Query: 1639 GRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFG 1683
RV +L K + TL+ + S+ AL N+ ++L +++F+FA+ G
Sbjct: 761 LRVFKLAKSWPTLNTLIKIIGNSVGALGNLTIILAIIVFVFALVG 805
Score = 87.0 bits (206), Expect = 5e-15
Identities = 69/291 (23%), Positives = 140/291 (48%), Gaps = 31/291 (10%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMI-----MPTTPTV----ESTEVIFTGIYTFE 180
+R+ I+ H F FII IL++ + + PTV E T+ +FT I+ FE
Sbjct: 1141 VRKTCYRIVEHSWFESFIIFMILLSSGSLAFEDYYLDQKPTVKALLEYTDRVFTFIFVFE 1200
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI------DLGNLAALRTFRVLR 234
+K +A GF Y +AW WLDF+++ ++ +++ ++ + ALRT R LR
Sbjct: 1201 MLLKWVAYGFK----KYFTNAWCWLDFLIVNISLISLTAKILEYSEVAPIKALRTLRALR 1256
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFP 294
L+ ++ G++ +V A++ ++ ++ +V+++ + +F++MG+ ++ G +C+
Sbjct: 1257 PLRALSRFEGMRVVVDALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKF-WRCINYTD 1315
Query: 295 EDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGY 354
+ S L+ N + C+ + + G + GY+ L +
Sbjct: 1316 GEFSLVPLSIVNNKSDCKIQNS----TGSFFWVNVKVNFDNVAMGYLALLQVAT-----F 1366
Query: 355 TSFDTFGWAFLSAFRLMTQDYWE-NLYQ-LFFVVIIFLGSFYLVNLILAIV 403
+ +A + + + Q WE N+Y L+FV+ I G F+ +NL + ++
Sbjct: 1367 KGWMDIMYAAVDSREVNMQPKWEDNVYMYLYFVIFIIFGGFFTLNLFVGVI 1417
Score = 80.2 bits (189), Expect = 5e-13
Identities = 59/181 (32%), Positives = 92/181 (50%), Gaps = 18/181 (9%)
Query: 1212 FKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKW 1271
F LI T + +V + L L + R L + + Y +FTVI+ E LIK
Sbjct: 116 FNLIRRTAIKVSVHSWFSLFITVTILVNCVCMTRTDLPEKIEY---VFTVIYTFEALIKI 172
Query: 1272 LALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAM 1327
LA GF Y + W WLDF ++ ++ + L G G+ RT R LR L+ +
Sbjct: 173 LARGFCLNEFTYLRDPWNWLDFSVITLAYVGTAIDLRGISGL------RTFRVLRALKTV 226
Query: 1328 SRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKCV--DM--NHT 1382
S + G++V+V AL+ ++ + +V ++ + +FA++G+QLF G KCV DM N T
Sbjct: 227 SVIPGLKVIVGALIHSVKKLADVTILTIFCLSVFALVGLQLFKGNLKNKCVKNDMAVNET 286
Query: 1383 T 1383
T
Sbjct: 287 T 287
Score = 78.2 bits (184), Expect = 2e-12
Identities = 41/108 (37%), Positives = 61/108 (56%), Gaps = 5/108 (4%)
Query: 724 EIIEQAGRQSRASELNVSVYYFPTAEDDEDGPTFKEKLLDCLMKGIDFFCVWDCCWLWLE 783
E +++ R RA + VS+ E +E ++K CL + +WDCC +W++
Sbjct: 599 EYLDEPFRAQRAMSV-VSIITSVLEELEES----EQKCPPCLTSLSQKYLIWDCCPMWVK 653
Query: 784 FQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGN 831
+ + LV DPF EL ITLCIVVNT+FMA++HH M + L+ GN
Sbjct: 654 LKTILFGLVTDPFAELTITLCIVVNTIFMAMEHHGMSPTFEAMLQIGN 701
Score = 73.7 bits (173), Expect = 5e-11
Identities = 46/159 (28%), Positives = 82/159 (51%), Gaps = 12/159 (7%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMP---TTPTVEST----EVIFTGIYTFESA 182
++ + ++ P L I I+VN I M M +PT E+ ++FT +T E
Sbjct: 654 LKTILFGLVTDPFAELTITLCIVVNTIFMAMEHHGMSPTFEAMLQIGNIVFTIFFTAEMV 713
Query: 183 VKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGNLAALRTFRVLRALKTVAI 241
K++A P+ Y + WN D +++ ++ + +G+ G+L+ LR+FR+LR K
Sbjct: 714 FKIIA----FDPYYYFQKKWNIFDCIIVTVSLLELGVAKKGSLSVLRSFRLLRVFKLAKS 769
Query: 242 VPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
P L T++ + SV L ++ I+ + VFAL+G Q+
Sbjct: 770 WPTLNTLIKIIGNSVGALGNLTIILAIIVFVFALVGKQL 808
Score = 68.1 bits (159), Expect = 2e-09
Identities = 42/170 (24%), Positives = 80/170 (47%), Gaps = 7/170 (4%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W L+ F L+ + + E + I+++++ +A+E H P + +L + +FT+ F
Sbjct: 651 WVKLKTILFGLVTDPFAELTITLCIVVNTIFMAME--HHGMSPTFEAMLQIGNIVFTIFF 708
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRP 1323
EM+ K +A YF W D IIV VSL+ A G + +R+ R LR
Sbjct: 709 TAEMVFKIIAFDPYYYFQKKWNIFDCIIVTVSLLELGVAKKG-----SLSVLRSFRLLRV 763
Query: 1324 LRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
+ + ++ + ++ ++ N+ ++ I +FA++G QL Y
Sbjct: 764 FKLAKSWPTLNTLIKIIGNSVGALGNLTIILAIIVFVFALVGKQLLGENY 813
Score = 47.2 bits (107), Expect = 0.005
Identities = 36/129 (27%), Positives = 64/129 (49%), Gaps = 15/129 (11%)
Query: 1571 LNMIFIVIFSSECLLKIFAL-----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFV 1625
+ +F VI++ E L+KI A + Y +PWN DF V+ + + I+ +
Sbjct: 156 IEYVFTVIYTFEALIKILARGFCLNEFTYLRDPWNWLDFSVITLAYVGTA----IDLRGI 211
Query: 1626 SPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMS 1685
S LR RV R L+ V G++ ++ AL S+ L ++ +L + +FA+ G+
Sbjct: 212 SG--LRTFRVL---RALKTVSVIPGLKVIVGALIHSVKKLADVTILTIFCLSVFALVGLQ 266
Query: 1686 FFM-HVKDK 1693
F ++K+K
Sbjct: 267 LFKGNLKNK 275
Score = 47.2 bits (107), Expect = 0.005
Identities = 38/170 (22%), Positives = 79/170 (46%), Gaps = 15/170 (8%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFESAV-- 183
P N + I+ F + I+ I +N I M++ T E I I F AV
Sbjct: 1461 PLNKFQGFVFDIVTRQAFDITIMVLICLNMITMMVETDDQSEEKTKILGKINQFFVAVFT 1520
Query: 184 -KVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM--GIDLGNLAA---------LRTFR 231
+ + + F L+ + Y + WN DF+V+ L+ ++ L +L + +R R
Sbjct: 1521 GECVMKMFALRQY-YFTNGWNVFDFIVVVLSIASLIFSAILKSLQSYFSPTLFRVIRLAR 1579
Query: 232 VLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+ R L+ + G++T++ A++ S+ L ++ +L + ++++ G+ +
Sbjct: 1580 IGRILRLIRAAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMSSF 1629
Score = 36.3 bits (80), Expect = 8.5
Identities = 25/124 (20%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 792 VFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISI 851
VFD V + ++ + + +L + + + ++ R+ +L ++ + L+
Sbjct: 1541 VFDFIVVVLSIASLIFSAILKSLQSY-FSPTLFRVIRLARIGRILRLIRAAKGIRTLLFA 1599
Query: 852 MGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMI 911
+ ++ AL N+ +L +++FI+++ GM F +V R+ G +NF F +S +
Sbjct: 1600 LMMSLPALFNIGLLLFLVMFIYSIFGMSSF-----PHV-RWEAGIDDMFNFQTFANSMLC 1653
Query: 912 VFRV 915
+F++
Sbjct: 1654 LFQI 1657
>UniRef50_Q2XVR7 Cluster: Voltage-gated sodium channel Nav1.4a; n=8;
Euteleostomi|Rep: Voltage-gated sodium channel Nav1.4a -
Fugu rubripes (Japanese pufferfish) (Takifugu rubripes)
Length = 1892
Score = 791 bits (1957), Expect = 0.0
Identities = 385/756 (50%), Positives = 535/756 (70%), Gaps = 17/756 (2%)
Query: 1169 DEDVVDDTPADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMI 1228
+ D+V+ P C + C +++P L D + W LR F ++E+ +FET +I MI
Sbjct: 1023 EPDLVE--PEACFTDNCVKRWPCLNVDISQGKGKKWWNLRKTCFTIVEHDWFETFIIFMI 1080
Query: 1229 LLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLD 1288
LLSS ALA ED+++ R ++ +L + D++FT IF IEML+KW+A GF+ YFTNAWCWLD
Sbjct: 1081 LLSSGALAFEDIYIERRRTVKIVLEFADKVFTFIFVIEMLLKWVAYGFKTYFTNAWCWLD 1140
Query: 1289 FIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIF 1348
F IV +SLI+ A L G + K++RTLRALRPLRA+SR +GMRVVVNAL+ AIPSIF
Sbjct: 1141 FFIVDISLISLSANLMGFSDLGPIKSLRTLRALRPLRALSRFEGMRVVVNALIGAIPSIF 1200
Query: 1349 NVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH-EIIPDKNACT-LENYT----W 1402
NVLLVCLIFWLIF+IMGV LFAGK+++C++ L ++ +K+ C L+ T W
Sbjct: 1201 NVLLVCLIFWLIFSIMGVNLFAGKFYRCINTTTAELFPISVVNNKSDCVALQEATQEARW 1260
Query: 1403 ENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXX 1462
N +N+D+V K YL L Q+ATFKGW+ IM A+DSREV QP E N+YMY+Y
Sbjct: 1261 VNVKVNYDNVAKGYLSLLQIATFKGWMDIMYPAVDSREVEEQPSYEINLYMYIYFVIFII 1320
Query: 1463 XXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPR 1522
TLNLFIGVIIDNFN+QKKK G ++FMTE+QKKYY AMKK+GSKKP K IPRP
Sbjct: 1321 FGSFFTLNLFIGVIIDNFNQQKKKLGDK-DIFMTEEQKKYYEAMKKLGSKKPQKPIPRPA 1379
Query: 1523 WRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSE 1582
Q +VF+ ++ + FD+ IM+ I LNM+TM ++ QS L +N+ FIV+F+ E
Sbjct: 1380 NLIQGLVFDFISQQFFDIFIMVLICLNMVTMMVETDDQSPAKEDFLFKVNVAFIVVFTGE 1439
Query: 1583 CLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVL 1642
C LK+FALR+++F WN+FDF+VV+ SI +LSDIIEKYFVSPTL RV+R+A++GR+L
Sbjct: 1440 CTLKLFALRHYFFTNGWNIFDFIVVILSIAGTMLSDIIEKYFVSPTLFRVIRLARIGRIL 1499
Query: 1643 RLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNF 1702
RL+KGA+GIRTLLFAL MSLPALFNI LLLFL+MFIF+IFGMS F +VK + G++D++NF
Sbjct: 1500 RLIKGARGIRTLLFALMMSLPALFNIGLLLFLIMFIFSIFGMSNFAYVKKEAGINDMFNF 1559
Query: 1703 KTFVQSMILLFQMSTSAGWDGVLDGIINEE--ECDLPDNERGS--PGNCGSATIGITYLL 1758
+TF S+I LFQ++TSAGWD +L ++N+E +CD G+ GNCG+ +G+ +
Sbjct: 1560 ETFGSSIICLFQITTSAGWDTLLLPMLNKEPPDCDPAFENPGTDVKGNCGNPMMGMVFFC 1619
Query: 1759 SYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQ 1818
SY++ISFL+V+NMYIA+ILEN++ A E+ + L ++D++M+ E W++FD G+Q+I Y Q
Sbjct: 1620 SYIIISFLVVVNMYIAIILENFNVAQEESGDVLCEEDFEMFNETWEKFDTGGTQFIEYSQ 1679
Query: 1819 LSDFLDVLEPPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTKDFFARKGNPIEETG 1878
LSDF D L+ PL++ KPN+ ++I MD+P+ GD + CVD+L A+T++ +
Sbjct: 1680 LSDFCDALQEPLRVAKPNRQRLIEMDLPLVIGDRIHCVDVLLAVTQEVLGDTIEMVAMRE 1739
Query: 1879 DLE----VGRPEEAGYEPVSSTLWRQREEYCARLIQ 1910
+E + P A Y P+++T+ ++ E+ A +IQ
Sbjct: 1740 SIEAKFNLNNPTSASYAPITTTVRQKEEDMAAVVIQ 1775
Score = 398 bits (979), Expect = e-108
Identities = 211/386 (54%), Positives = 272/386 (70%), Gaps = 41/386 (10%)
Query: 61 PQPDATLEQGLPLPVRMQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNA 120
P P+ LE G LP+ + G P EL TPLEDIDPFY Q TFVV++KG I+RF+A A
Sbjct: 46 PTPNPDLEAGKSLPM-IFGDPPSELLGTPLEDIDPFYKAQKTFVVVTKGNTIYRFNAEPA 104
Query: 121 LWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVEST-EVIFTGIYTF 179
+IL PF+ +RR AI IL+H LFS I+ TIL NC+ M M P T E +FTGIYTF
Sbjct: 105 CYILSPFSLVRRGAIKILIHSLFSTLIMITILSNCVFMTMSNPPAWSKTVEYVFTGIYTF 164
Query: 180 ESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTV 239
E+ VKV++RGF + PFT+LRD WNWLDF+VI++AY+T +DLGN++ALRTFRVLRALKT+
Sbjct: 165 EATVKVLSRGFCVGPFTFLRDPWNWLDFMVISMAYITEFVDLGNVSALRTFRVLRALKTI 224
Query: 240 AIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVK-------- 291
++PGLKTIV A+I+SVK + DV+ILT+F+L+VFAL+GLQ++MG L KC++
Sbjct: 225 TVIPGLKTIVAALIQSVKKMVDVMILTVFALAVFALVGLQLFMGNLRHKCIRWPIANETA 284
Query: 292 -------VFPE-----DGSWGNLT-DEN----WERFCQN-ETNWYGEGG-DYPLCGNSSG 332
VF + D +W N T D N + + +N E ++ EG D LCGNS+
Sbjct: 285 SELFNGTVFNDTLSYNDTTWLNDTLDSNSTFDFTEYIENAENQYFLEGSKDALLCGNSTD 344
Query: 333 AGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ----------- 381
AG+C GY+C++ G NPNYGYTSFD+FGWAFL+ FRLMTQD WE+L+Q
Sbjct: 345 AGKCPEGYLCMKA-GRNPNYGYTSFDSFGWAFLALFRLMTQDNWESLFQLTLRAAGQTYM 403
Query: 382 LFFVVIIFLGSFYLVNLILAIVAMSY 407
LFFVV+IFLGSFYL+NLILA+VAM+Y
Sbjct: 404 LFFVVVIFLGSFYLINLILAVVAMAY 429
Score = 172 bits (419), Expect = 7e-41
Identities = 85/170 (50%), Positives = 108/170 (63%), Gaps = 2/170 (1%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+S LRVFKLAKSWPTLN+LI I+G ++GALGNLT VL II+FIFAV+GMQLFGK+Y
Sbjct: 702 LRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYK 761
Query: 887 DYVDRF-PDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCM-LVGDVSCIPFFLATVV 944
D V + D +LPRW+ DF HSF+IVFR+LCGEWIE+MWDCM + G C+ F+ +V
Sbjct: 762 DCVCKISSDCELPRWHMNDFFHSFLIVFRILCGEWIETMWDCMEVAGAGMCLVVFMMVMV 821
Query: 945 IXXXXXXXXXXXXXXXXXXXXXXXTPTADQDTNKIAEAFNRISRFIDWIK 994
I D + N + A RI+R +W+K
Sbjct: 822 IGNLVVLNLFLALLLSSFSGDNLSVGDDDGELNNLQIAIGRITRGGNWLK 871
Score = 94.3 bits (224), Expect = 3e-17
Identities = 74/258 (28%), Positives = 130/258 (50%), Gaps = 33/258 (12%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL- 1590
+V D D+ I + I LN L M ++HY +E F +L N++F IF++E K+ A+
Sbjct: 608 VVMDPFVDLAITICIVLNTLFMAMEHYPMTEEFDYMLSVGNLVFTGIFAAEMFFKLIAMD 667
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
Y+YF WN+FD ++V S++ L L+++ L V+R ++ RV +L K
Sbjct: 668 PYYYFQVGWNIFDSIIVTLSLVELGLANV--------QGLSVLRSFRLLRVFKLAKSWPT 719
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF-MHVKD---KGGLD---DVYNFK 1703
+ L+ + S+ AL N+ L+L +++FIFA+ GM F KD K D ++
Sbjct: 720 LNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKDCVCKISSDCELPRWHMN 779
Query: 1704 TFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVI 1763
F S +++F++ W I +C E G C + + +VI
Sbjct: 780 DFFHSFLIVFRI-LCGEW------IETMWDC----MEVAGAGMC------LVVFMMVMVI 822
Query: 1764 SFLIVINMYIAVILENYS 1781
L+V+N+++A++L ++S
Sbjct: 823 GNLVVLNLFLALLLSSFS 840
Score = 79.4 bits (187), Expect = 9e-13
Identities = 32/62 (51%), Positives = 45/62 (72%)
Query: 770 DFFCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKS 829
D F W+CC W+ F+K+V +V DPFV+L IT+CIV+NTLFMA++H+ M ++ D L
Sbjct: 587 DIFLKWNCCEKWVVFKKWVHFVVMDPFVDLAITICIVLNTLFMAMEHYPMTEEFDYMLSV 646
Query: 830 GN 831
GN
Sbjct: 647 GN 648
Score = 79.0 bits (186), Expect = 1e-12
Identities = 72/295 (24%), Positives = 136/295 (46%), Gaps = 40/295 (13%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMP--------TTPTV-ESTEVIFTGIYTFE 180
+R+ I+ H F FII IL++ + T V E + +FT I+ E
Sbjct: 1059 LRKTCFTIVEHDWFETFIIFMILLSSGALAFEDIYIERRRTVKIVLEFADKVFTFIFVIE 1118
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVT-----MGI-DLGNLAALRTFRVLR 234
+K +A GF TY +AW WLDF ++ ++ ++ MG DLG + +LRT R LR
Sbjct: 1119 MLLKWVAYGFK----TYFTNAWCWLDFFIVDISLISLSANLMGFSDLGPIKSLRTLRALR 1174
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG----VLTQKCV 290
L+ ++ G++ +V A+I ++ ++ +V+++ + +F++MG+ ++ G +
Sbjct: 1175 PLRALSRFEGMRVVVNALIGAIPSIFNVLLVCLIFWLIFSIMGVNLFAGKFYRCINTTTA 1234
Query: 291 KVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNP 350
++FP N +D + E W +Y GY+ L
Sbjct: 1235 ELFP-ISVVNNKSDCVALQEATQEARWVNVKVNY---------DNVAKGYLSLLQIAT-- 1282
Query: 351 NYGYTSFDTFGWAFLSAFRLMTQDYWE-NLYQ-LFFVVIIFLGSFYLVNLILAIV 403
+ + + + + + Q +E NLY ++FV+ I GSF+ +NL + ++
Sbjct: 1283 ---FKGWMDIMYPAVDSREVEEQPSYEINLYMYIYFVIFIIFGSFFTLNLFIGVI 1334
Score = 76.2 bits (179), Expect = 9e-12
Identities = 47/174 (27%), Positives = 83/174 (47%), Gaps = 7/174 (4%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W + ++ + + + A+ I+L++L +A+E H P +L + +FT IF
Sbjct: 598 WVVFKKWVHFVVMDPFVDLAITICIVLNTLFMAME--HYPMTEEFDYMLSVGNLVFTGIF 655
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRP 1323
EM K +A+ YF W D IIV +SL+ G +Q +R+ R LR
Sbjct: 656 AAEMFFKLIAMDPYYYFQVGWNIFDSIIVTLSLVEL-----GLANVQGLSVLRSFRLLRV 710
Query: 1324 LRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCV 1377
+ + +++ + ++ ++ N+ LV I IFA++G+QLF Y CV
Sbjct: 711 FKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKDCV 764
Score = 73.7 bits (173), Expect = 5e-11
Identities = 44/163 (26%), Positives = 86/163 (52%), Gaps = 13/163 (7%)
Query: 136 YILVHPLFSLFIITTILVNCILMIMPTTPTVESTE-------VIFTGIYTFESAVKVMAR 188
++++ P L I I++N + M M P E + ++FTGI+ E K++A
Sbjct: 607 FVVMDPFVDLAITICIVLNTLFMAMEHYPMTEEFDYMLSVGNLVFTGIFAAEMFFKLIA- 665
Query: 189 GFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGNLAALRTFRVLRALKTVAIVPGLKT 247
+ P+ Y + WN D +++ L+ V +G+ ++ L+ LR+FR+LR K P L
Sbjct: 666 ---MDPYYYFQVGWNIFDSIIVTLSLVELGLANVQGLSVLRSFRLLRVFKLAKSWPTLNM 722
Query: 248 IVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCV 290
++ + SV L ++ ++ + +FA++G+Q++ G + CV
Sbjct: 723 LIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLF-GKSYKDCV 764
Score = 71.7 bits (168), Expect = 2e-10
Identities = 44/176 (25%), Positives = 92/176 (52%), Gaps = 19/176 (10%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+R K++ ++ F T ++ IL + + + + + P + Y +FT I+ E
Sbjct: 114 VRRGAIKILIHSLFSTLIMITILSNCVFMTMSNP-----PAWSKTVEY---VFTGIYTFE 165
Query: 1267 MLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALR 1322
+K L+ GF + + W WLDF+++ ++ ++ G + A +T R LRAL+
Sbjct: 166 ATVKVLSRGFCVGPFTFLRDPWNWLDFMVISMA---YITEFVDLGNVSALRTFRVLRALK 222
Query: 1323 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKCV 1377
+ + G++ +V AL+Q++ + +V+++ + +FA++G+QLF G KC+
Sbjct: 223 TITVIP---GLKTIVAALIQSVKKMVDVMILTVFALAVFALVGLQLFMGNLRHKCI 275
Score = 51.2 bits (117), Expect = 3e-04
Identities = 37/163 (22%), Positives = 79/163 (48%), Gaps = 20/163 (12%)
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL 1590
+I+ F +IM+ I N + MT+ + +S ++Y +F I++ E +K+ +
Sbjct: 120 KILIHSLFSTLIMITILSNCVFMTMSN---PPAWSKTVEY---VFTGIYTFEATVKVLSR 173
Query: 1591 RY-----HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLV 1645
+ + +PWN DF+V+ + ++ FV + +R +V R L+ +
Sbjct: 174 GFCVGPFTFLRDPWNWLDFMVISMAYIT---------EFVDLGNVSALRTFRVLRALKTI 224
Query: 1646 KGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
G++T++ AL S+ + ++ +L + +FA+ G+ FM
Sbjct: 225 TVIPGLKTIVAALIQSVKKMVDVMILTVFALAVFALVGLQLFM 267
Score = 46.4 bits (105), Expect = 0.008
Identities = 40/169 (23%), Positives = 81/169 (47%), Gaps = 21/169 (12%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT---TPTVE----STEVIFTGIYT 178
P N I+ + + F +FI+ I +N + M++ T +P E V F ++T
Sbjct: 1378 PANLIQGLVFDFISQQFFDIFIMVLICLNMVTMMVETDDQSPAKEDFLFKVNVAFIVVFT 1437
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV-TMGIDLGN--------LAALRT 229
E +K+ F L+ + + + WN DF+V+ L+ TM D+ +R
Sbjct: 1438 GECTLKL----FALRHY-FFTNGWNIFDFIVVILSIAGTMLSDIIEKYFVSPTLFRVIRL 1492
Query: 230 FRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGL 278
R+ R L+ + G++T++ A++ S+ L ++ +L + +F++ G+
Sbjct: 1493 ARIGRILRLIKGARGIRTLLFALMMSLPALFNIGLLLFLIMFIFSIFGM 1541
Score = 37.5 bits (83), Expect = 3.7
Identities = 38/182 (20%), Positives = 78/182 (42%), Gaps = 11/182 (6%)
Query: 749 EDDEDGPTFKEKLLDCLMKGIDFFCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVN 808
E D+ P ++ L + I F +C + Y ++ F + + L I
Sbjct: 1413 ETDDQSPAKEDFLFKVNVAFIVVF-TGECTLKLFALRHYFFTNGWNIFDFIVVILSIAGT 1471
Query: 809 TLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCI 868
L ++ + + + + ++ R+ +L K + L+ + ++ AL N+ +L +
Sbjct: 1472 MLSDIIEKYFVSPTLFRVIRLARIGRILRLIKGARGIRTLLFALMMSLPALFNIGLLLFL 1531
Query: 869 IIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCM 928
I+FIF++ GM F YV + G +NF F S + +F++ + WD +
Sbjct: 1532 IMFIFSIFGMSNFA-----YVKK-EAGINDMFNFETFGSSIICLFQIT----TSAGWDTL 1581
Query: 929 LV 930
L+
Sbjct: 1582 LL 1583
>UniRef50_Q25150 Cluster: Voltage-gated sodium channel; n=1;
Halocynthia roretzi|Rep: Voltage-gated sodium channel -
Halocynthia roretzi (Sea squirt)
Length = 2049
Score = 767 bits (1897), Expect = 0.0
Identities = 377/762 (49%), Positives = 529/762 (69%), Gaps = 27/762 (3%)
Query: 1174 DDTPADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSL 1233
+D P+ C P++ ++ D W +R +++IE+ +FE+ +I MI+LSS
Sbjct: 1217 EDVPSPCWPDKWKERVACCDPVVDEGLCLVWWNMRKICYRIIEHAWFESFIILMIMLSSG 1276
Query: 1234 ALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVM 1293
ALA EDV+L + LQ +L Y DRIFT +F EML+KW+ GF+KYFTNAWCWLDF+IV
Sbjct: 1277 ALAFEDVYLKDKIGLQRVLKYADRIFTYVFIFEMLLKWVGYGFKKYFTNAWCWLDFLIVG 1336
Query: 1294 VSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLV 1353
VSLI+ +A G I + +++RTLRALRPLRAMSR +GM+VVVNALV AIPSIFNVLLV
Sbjct: 1337 VSLISLIAEALGMDQIGSIRSLRTLRALRPLRAMSRFRGMKVVVNALVGAIPSIFNVLLV 1396
Query: 1354 CLIFWLIFAIMGVQLFAGKYFKCVDMN--------HTTLSHEIIPDKNACTL----ENYT 1401
CLIFWLIF+IMGV FAGK+ KC++ + TL P+ N+ EN T
Sbjct: 1397 CLIFWLIFSIMGVNFFAGKFRKCLNTTSGISLPAENFTLYGVTYPEINSTVCKYIHENVT 1456
Query: 1402 ----WENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYX 1457
W NS +NFD+ YL L QVAT+KGW++IM DA+D +QP E ++ Y Y
Sbjct: 1457 QDIMWRNSKINFDNAFSGYLALLQVATYKGWMEIMYDAVDVTYTNKQPKFENSVGYYFYF 1516
Query: 1458 XXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKA 1517
TLNLFIGVIIDNF++QKKK GG ++FMTE+Q+KYYNAMKK+GSK+P K
Sbjct: 1517 VAFILFGSFFTLNLFIGVIIDNFSQQKKKLGGQ-DIFMTEEQRKYYNAMKKLGSKQPQKP 1575
Query: 1518 IPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIV 1577
+PRP+ QA VF+IV + F++ IM+ I NM TM ++++ + VL+Y+N +FI
Sbjct: 1576 VPRPKNELQAWVFDIVVHQTFEIAIMILIVTNMFTMMIEYHDMPKNLMDVLEYINYVFIA 1635
Query: 1578 IFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAK 1637
IF+ ECLLK ALR++YF PWN+FDF+VV+ S++ ++++I++YF+ PTL R++R+A+
Sbjct: 1636 IFTGECLLKWCALRFYYFKNPWNVFDFIVVILSVVGSTMNEVIKQYFLQPTLFRIIRLAR 1695
Query: 1638 VGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLD 1697
+GR+LRL++GAKGIRTLLFAL MSLPALFNI LLL LVMFI++IFGMS F +V G+D
Sbjct: 1696 IGRILRLIRGAKGIRTLLFALMMSLPALFNIALLLVLVMFIYSIFGMSQFAYVHRGDGID 1755
Query: 1698 DVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEE--ECDL---PDNERGSPGNCGSATI 1752
D++NF+TF S + LF ++TSAGW G+L I++ + +C++ DN G G+CG+ I
Sbjct: 1756 DIFNFETFPNSFLCLFMITTSAGWAGLLSPIMDSDAPDCNILLQNDNPNGR-GDCGNPKI 1814
Query: 1753 GITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQ 1812
GI + ++YL+++FLIV+NMYIA+ILEN+ ATE+ + L +DD++M+YEIW+RFDP +Q
Sbjct: 1815 GIIFFVTYLIMTFLIVVNMYIAIILENFGVATEESADPLGEDDFEMFYEIWERFDPKATQ 1874
Query: 1813 YIRYDQLSDFLDVLEPPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTK----DFFA 1868
+I Y+ LSDF+D L+ PL++ KPN +I+MD+P+ GD + C+D+L ALTK + A
Sbjct: 1875 FIAYEHLSDFVDNLDLPLKVPKPNFDTLIAMDLPMVMGDRLHCLDVLFALTKRVLGESDA 1934
Query: 1869 RKGNPIEETGDLEVGRPEEAGYEPVSSTLWRQREEYCARLIQ 1910
+G + P + YEP+++TL R++EE A +IQ
Sbjct: 1935 LEGLRSQMEDKFMEANPSKVSYEPITTTLRRKQEEMSAVIIQ 1976
Score = 227 bits (555), Expect = 2e-57
Identities = 124/247 (50%), Positives = 157/247 (63%), Gaps = 17/247 (6%)
Query: 61 PQPDATLEQGLPLPVRMQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNA 120
P PD LEQG LP +QG P + L D DPFY N+ T+VV K K I+RFS A
Sbjct: 53 PNPD--LEQGKTLPEYLQGDLPDKYLCQALVDPDPFYANKKTYVVFDKNKVIYRFSCEKA 110
Query: 121 LWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFE 180
L+ L P NP+RR+A I +H +F+ I+ TILVNC M V+ E F IYTFE
Sbjct: 111 LFCLGPLNPVRRIANMIYIHSVFNSVIMLTILVNCGFMAYGED--VDIVEKTFLAIYTFE 168
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN-------------LAAL 227
+ VK+ +RGFIL FTYLRD WN LD VI AY+ + + L +AAL
Sbjct: 169 AVVKIFSRGFILSSFTYLRDPWNILDISVIFTAYLDIVMALAQKASDGGKAQKIPGMAAL 228
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQ 287
R FRVLRALK ++ +PGLK IV A+IESVK L+DV+ILT+F LSVFAL+GLQ++MG L
Sbjct: 229 RAFRVLRALKAISAIPGLKAIVAALIESVKALKDVMILTLFCLSVFALIGLQLFMGSLRN 288
Query: 288 KCVKVFP 294
KC++ +P
Sbjct: 289 KCIRQWP 295
Score = 141 bits (342), Expect = 2e-31
Identities = 67/122 (54%), Positives = 88/122 (72%), Gaps = 5/122 (4%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L++ +RVFKLAKSWPTLN+LI I+G +MG+LGNLT +L I++FIFAV+GMQLF + Y
Sbjct: 889 LRTFRLMRVFKLAKSWPTLNMLIKIIGNSMGSLGNLTLILIIVLFIFAVVGMQLFRERYK 948
Query: 887 DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCM-LVGDVS--CIPFFLATV 943
+ RW+ DF HSF+IVFR+LCGEWIE+MWDC+ GD+ C+P FL
Sbjct: 949 E--AELAGNLNMRWHMKDFGHSFLIVFRILCGEWIETMWDCLRWGGDIRGLCVPVFLLVQ 1006
Query: 944 VI 945
V+
Sbjct: 1007 VV 1008
Score = 134 bits (325), Expect = 2e-29
Identities = 65/115 (56%), Positives = 79/115 (68%), Gaps = 12/115 (10%)
Query: 304 DENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWA 363
++ WE + +NE N+ G LCGN + G+C GY C+ G NPN+GYTSFD F WA
Sbjct: 356 NQTWENWMENECNYCFVRGAAWLCGNGTDTGKCWEGYECVLT-GENPNFGYTSFDNFSWA 414
Query: 364 FLSAFRLMTQDYWENLYQL-----------FFVVIIFLGSFYLVNLILAIVAMSY 407
FLS FRLM QDYWENLYQL FF+V+IFLGSFYL+NLILA+VAM+Y
Sbjct: 415 FLSLFRLMAQDYWENLYQLTLRANGKVYLIFFMVVIFLGSFYLINLILAVVAMAY 469
Score = 101 bits (243), Expect = 2e-19
Identities = 58/189 (30%), Positives = 104/189 (55%), Gaps = 13/189 (6%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR 1591
I D D+ I + I +N MT ++ E+++ +L+ N++F VIF++E +LK+ ++
Sbjct: 795 ICEDPFLDLFITICIIVNTAFMTAEYQPMEESYARILEVANLVFTVIFTAEMVLKVVGMQ 854
Query: 1592 -YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
+ YF +PWN FD V+V FS+L L + L V+R ++ RV +L K
Sbjct: 855 PFQYFQDPWNCFDSVIVSFSLLEYALQSVGG--------LSVLRTFRLMRVFKLAKSWPT 906
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF----MHVKDKGGLDDVYNFKTFV 1706
+ L+ + S+ +L N+ L+L +V+FIFA+ GM F + G L+ ++ K F
Sbjct: 907 LNMLIKIIGNSMGSLGNLTLILIIVLFIFAVVGMQLFRERYKEAELAGNLNMRWHMKDFG 966
Query: 1707 QSMILLFQM 1715
S +++F++
Sbjct: 967 HSFLIVFRI 975
Score = 85.4 bits (202), Expect = 1e-14
Identities = 50/178 (28%), Positives = 91/178 (51%), Gaps = 13/178 (7%)
Query: 113 FRFSATNALW-ILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVES--- 168
++F+ +W +N I ++ I P LFI I+VN M P ES
Sbjct: 770 YKFTNIFCIWNCCGAWNYIHKICKIICEDPFLDLFITICIIVNTAFMTAEYQPMEESYAR 829
Query: 169 ----TEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID-LGN 223
++FT I+T E +KV+ +QPF Y +D WN D V+++ + + + +G
Sbjct: 830 ILEVANLVFTVIFTAEMVLKVVG----MQPFQYFQDPWNCFDSVIVSFSLLEYALQSVGG 885
Query: 224 LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
L+ LRTFR++R K P L ++ + S+ +L ++ ++ + L +FA++G+Q++
Sbjct: 886 LSVLRTFRLMRVFKLAKSWPTLNMLIKIIGNSMGSLGNLTLILIIVLFIFAVVGMQLF 943
Score = 74.5 bits (175), Expect = 3e-11
Identities = 44/176 (25%), Positives = 96/176 (54%), Gaps = 20/176 (11%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMPTT---------PTVESTEVIFTGIYTFE 180
+R++ I+ H F FII I+++ + ++ + IFT ++ FE
Sbjct: 1250 MRKICYRIIEHAWFESFIILMIMLSSGALAFEDVYLKDKIGLQRVLKYADRIFTYVFIFE 1309
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM-----GID-LGNLAALRTFRVLR 234
+K + GF Y +AW WLDF+++ ++ +++ G+D +G++ +LRT R LR
Sbjct: 1310 MLLKWVGYGFK----KYFTNAWCWLDFLIVGVSLISLIAEALGMDQIGSIRSLRTLRALR 1365
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCV 290
L+ ++ G+K +V A++ ++ ++ +V+++ + +F++MG+ + G +KC+
Sbjct: 1366 PLRAMSRFRGMKVVVNALVGAIPSIFNVLLVCLIFWLIFSIMGVNFFAGKF-RKCL 1420
Score = 70.1 bits (164), Expect = 6e-10
Identities = 45/164 (27%), Positives = 84/164 (51%), Gaps = 6/164 (3%)
Query: 1210 KTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLI 1269
K K+I F IT+ ++ + A + + P IL + +FTVIF EM++
Sbjct: 790 KICKIICEDPFLDLFITICIIVNTAFMTAE-YQPMEESYARILEVANLVFTVIFTAEMVL 848
Query: 1270 KWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSR 1329
K + + +YF + W D +IV SL+ + AL GG+ +T R +R + ++
Sbjct: 849 KVVGMQPFQYFQDPWNCFDSVIVSFSLLEY--ALQSVGGLSVLRTFRLMRVFKLAKSWPT 906
Query: 1330 MQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
+ +++ + ++ S+ N+ L+ +I IFA++G+QLF +Y
Sbjct: 907 LN---MLIKIIGNSMGSLGNLTLILIIVLFIFAVVGMQLFRERY 947
Score = 69.3 bits (162), Expect = 1e-09
Identities = 27/72 (37%), Positives = 42/72 (58%)
Query: 760 KLLDCLMKGIDFFCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNM 819
K C K + FC+W+CC W K ++ DPF++LFIT+CI+VNT FM ++ M
Sbjct: 764 KCSPCWYKFTNIFCIWNCCGAWNYIHKICKIICEDPFLDLFITICIIVNTAFMTAEYQPM 823
Query: 820 DKDMDKALKSGN 831
++ + L+ N
Sbjct: 824 EESYARILEVAN 835
Score = 64.5 bits (150), Expect = 3e-08
Identities = 38/135 (28%), Positives = 73/135 (54%), Gaps = 12/135 (8%)
Query: 1255 MDRIFTVIFFIEMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALC---GAG 1307
+++ F I+ E ++K + GF Y + W LD ++ + ++ V AL G
Sbjct: 157 VEKTFLAIYTFEAVVKIFSRGFILSSFTYLRDPWNILDISVIFTAYLDIVMALAQKASDG 216
Query: 1308 G----IQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAI 1363
G I +R R LR L+A+S + G++ +V AL++++ ++ +V+++ L +FA+
Sbjct: 217 GKAQKIPGMAALRAFRVLRALKAISAIPGLKAIVAALIESVKALKDVMILTLFCLSVFAL 276
Query: 1364 MGVQLFAGKY-FKCV 1377
+G+QLF G KC+
Sbjct: 277 IGLQLFMGSLRNKCI 291
Score = 55.6 bits (128), Expect = 1e-05
Identities = 32/131 (24%), Positives = 68/131 (51%), Gaps = 11/131 (8%)
Query: 1568 LDYLNMIFIVIFSSECLLKIFAL-----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEK 1622
+D + F+ I++ E ++KIF+ + Y +PWN+ D V+ + L +V++ + +K
Sbjct: 154 VDIVEKTFLAIYTFEAVVKIFSRGFILSSFTYLRDPWNILDISVIFTAYLDIVMA-LAQK 212
Query: 1623 YFVSPTLLRV-----VRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMF 1677
++ +R +V R L+ + G++ ++ AL S+ AL ++ +L +
Sbjct: 213 ASDGGKAQKIPGMAALRAFRVLRALKAISAIPGLKAIVAALIESVKALKDVMILTLFCLS 272
Query: 1678 IFAIFGMSFFM 1688
+FA+ G+ FM
Sbjct: 273 VFALIGLQLFM 283
Score = 48.4 bits (110), Expect = 0.002
Identities = 41/169 (24%), Positives = 79/169 (46%), Gaps = 21/169 (12%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMI-----MPTT--PTVESTEVIFTGIYT 178
P N ++ I+VH F + I+ I+ N M+ MP +E +F I+T
Sbjct: 1579 PKNELQAWVFDIVVHQTFEIAIMILIVTNMFTMMIEYHDMPKNLMDVLEYINYVFIAIFT 1638
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV--TMG-------IDLGNLAALRT 229
E +K A F Y ++ WN DF+V+ L+ V TM + +R
Sbjct: 1639 GECLLKWCALRFY-----YFKNPWNVFDFIVVILSVVGSTMNEVIKQYFLQPTLFRIIRL 1693
Query: 230 FRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGL 278
R+ R L+ + G++T++ A++ S+ L ++ +L + + ++++ G+
Sbjct: 1694 ARIGRILRLIRGAKGIRTLLFALMMSLPALFNIALLLVLVMFIYSIFGM 1742
Score = 47.2 bits (107), Expect = 0.005
Identities = 30/140 (21%), Positives = 67/140 (47%), Gaps = 6/140 (4%)
Query: 776 DCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRV 835
+C W + Y ++ F + + L +V +T+ + + + + + ++ R+
Sbjct: 1640 ECLLKWCALRFYYFKNPWNVFDFIVVILSVVGSTMNEVIKQYFLQPTLFRIIRLARIGRI 1699
Query: 836 FKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDG 895
+L + + L+ + ++ AL N+ +L +++FI+++ GM F YV R DG
Sbjct: 1700 LRLIRGAKGIRTLLFALMMSLPALFNIALLLVLVMFIYSIFGMSQFA-----YVHR-GDG 1753
Query: 896 DLPRWNFTDFMHSFMIVFRV 915
+NF F +SF+ +F +
Sbjct: 1754 IDDIFNFETFPNSFLCLFMI 1773
Score = 37.9 bits (84), Expect = 2.8
Identities = 26/96 (27%), Positives = 50/96 (52%), Gaps = 8/96 (8%)
Query: 826 ALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF-GKN 884
AL++ LR K + P L +++ + ++ AL ++ + + +FA++G+QLF G
Sbjct: 227 ALRAFRVLRALKAISAIPGLKAIVAALIESVKALKDVMILTLFCLSVFALIGLQLFMGSL 286
Query: 885 YVDYVDRFP----DGDLPRW---NFTDFMHSFMIVF 913
+ ++P D + W N+TDF HS +V+
Sbjct: 287 RNKCIRQWPPYVNDELMTMWLTQNYTDFNHSNPLVY 322
>UniRef50_Q4RYI3 Cluster: Chromosome 2 SCAF14976, whole genome shotgun
sequence; n=7; Euteleostomi|Rep: Chromosome 2 SCAF14976,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1785
Score = 767 bits (1896), Expect = 0.0
Identities = 380/764 (49%), Positives = 524/764 (68%), Gaps = 32/764 (4%)
Query: 1177 PADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALA 1236
P C + C + +P L D + W LR F ++E+ +FET +I MILLSS ALA
Sbjct: 963 PEACFTDNCVKHWPCLNVDVTQGQGKKWWNLRKTCFTIVEHDWFETFIIFMILLSSGALA 1022
Query: 1237 LEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSL 1296
ED+++ R ++ IL + D++FT IF +EM++KW+A GF+ YFTNAWCWLDF IV +SL
Sbjct: 1023 FEDIYIERRRTVKIILEFADKVFTFIFVLEMVLKWVAYGFKTYFTNAWCWLDFFIVDISL 1082
Query: 1297 INFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLI 1356
I+ A L G + K++RTLRALRPLRA+SR +GMRVVVNAL+ AIPSIFNVLLVCLI
Sbjct: 1083 ISLSANLMGLSDLGPIKSLRTLRALRPLRALSRFEGMRVVVNALIGAIPSIFNVLLVCLI 1142
Query: 1357 FWLIFAIMGVQLFAGKYFKCVDMNHTTL-SHEIIPDKNAC-----TLENYTWENSPMNFD 1410
FWLIF+IMGV LFAGK++ C++ L ++ +K+ C + W N +N+D
Sbjct: 1143 FWLIFSIMGVNLFAGKFYHCINTTTQELFPISVVNNKSDCMAVQEATQEARWVNVKVNYD 1202
Query: 1411 HVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLN 1470
+VGK YL L Q+ATFKGW IM A+DSREV QP E N+YMY+Y TLN
Sbjct: 1203 NVGKGYLSLLQIATFKGWTAIMYAAVDSREVEEQPSYEINLYMYIYFVIFIIFGAFFTLN 1262
Query: 1471 LFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPR-WRP---- 1525
LFIGVIIDNFN+QK+K + ++FMTE+QKKYY AMKK+GSKKP K IPRP P
Sbjct: 1263 LFIGVIIDNFNQQKRKI--NKDIFMTEEQKKYYEAMKKLGSKKPQKPIPRPTVSHPEVSD 1320
Query: 1526 -----------QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMI 1574
Q +VF+ ++ + FD+ IM+ I LNM+TM ++ QS L +N+
Sbjct: 1321 PAQKERSQNLIQGMVFDFISQQFFDIFIMVLICLNMVTMMVETDDQSPEKEDFLFKVNVA 1380
Query: 1575 FIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVR 1634
FIV+F+ EC+LK+ ALR ++F WN+FDFVVV+ SI +LSD+IEKYFVSPTL RV+R
Sbjct: 1381 FIVVFTGECMLKLIALRQYFFTNGWNIFDFVVVILSIAGTMLSDLIEKYFVSPTLFRVIR 1440
Query: 1635 VAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKG 1694
+A++GR+LRL+KGA+GIRTLLFAL MSLPALFNI LLLFL+MFIF+IFGMS F +VK +
Sbjct: 1441 LARIGRILRLIKGARGIRTLLFALMMSLPALFNIGLLLFLIMFIFSIFGMSNFAYVKKEA 1500
Query: 1695 GLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEE--ECDLPDNERGS--PGNCGSA 1750
G+DD++NF+TF S+I LFQ++TS GWD +L I+N+E +CD G+ GNCG+
Sbjct: 1501 GIDDMFNFETFGSSIICLFQITTSGGWDQILLPILNKEPPDCDPTLENPGTDVKGNCGNP 1560
Query: 1751 TIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDG 1810
+G+ + SY++ISFL+V+NMYIA+ILEN++ A E+ + L ++D++M+ E W++FD G
Sbjct: 1561 MVGMMFFCSYIIISFLVVVNMYIAIILENFNVAQEESGDALCEEDFEMFNETWEKFDTGG 1620
Query: 1811 SQYIRYDQLSDFLDVLEPPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTKDFFARK 1870
+Q+I Y QLSDF D L+ PL++ KPN+ ++I MD+P+ GD + CVD+L A+T++
Sbjct: 1621 TQFIEYSQLSDFCDTLQEPLRVAKPNRLRLIEMDLPLVIGDRIHCVDVLLAVTQEVLGDT 1680
Query: 1871 GNPIEETGDLE----VGRPEEAGYEPVSSTLWRQREEYCARLIQ 1910
+ +E + P Y P+++T+ ++ EE A +IQ
Sbjct: 1681 IEMVAMRESIEAKFNLNNPTSVSYAPITTTVRQKEEEMAAVVIQ 1724
Score = 167 bits (405), Expect = 4e-39
Identities = 83/170 (48%), Positives = 107/170 (62%), Gaps = 2/170 (1%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+S LRVFKLAKSWPTLN+LI I+G ++GALGNLT VL II+FIFAV+GMQLFGK+Y
Sbjct: 650 LRSFRLLRVFKLAKSWPTLNMLIKIIGSSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYK 709
Query: 887 DYVDRF-PDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCM-LVGDVSCIPFFLATVV 944
D V + + +LPRW+ DF HSF+IVFR+LCGEWIE+MW CM + G C+ F+ +V
Sbjct: 710 DCVCKISTECELPRWHMNDFFHSFLIVFRILCGEWIENMWACMEVAGAGMCLVVFMMVMV 769
Query: 945 IXXXXXXXXXXXXXXXXXXXXXXXTPTADQDTNKIAEAFNRISRFIDWIK 994
I D + N + A RI+R +W+K
Sbjct: 770 IGNLVVLNLFLALLLSSFSGDNLSIGEDDGEMNNLQIAIGRITRGGNWLK 819
Score = 115 bits (276), Expect = 2e-23
Identities = 55/84 (65%), Positives = 65/84 (77%), Gaps = 12/84 (14%)
Query: 335 QCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ-----------LF 383
+C GY C++ G NPNYGYTSFD+FGWAFL+ FRLMTQD WENL+Q LF
Sbjct: 306 RCPEGYECMKA-GRNPNYGYTSFDSFGWAFLALFRLMTQDCWENLFQQTLRAAGKTYMLF 364
Query: 384 FVVIIFLGSFYLVNLILAIVAMSY 407
FVV+IFLGSFYL+NLILA+VAM+Y
Sbjct: 365 FVVVIFLGSFYLINLILAVVAMAY 388
Score = 93.5 bits (222), Expect = 5e-17
Identities = 73/258 (28%), Positives = 130/258 (50%), Gaps = 33/258 (12%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL- 1590
+V D D+ I + I LN L M ++HY ++ F +L N++F IF++E K+ A+
Sbjct: 556 VVMDPFVDLAITICIVLNTLFMAMEHYPMTQEFDYMLSVGNLVFTGIFAAEMFFKLIAMD 615
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
Y+YF WN+FD ++V S++ L L+++ L V+R ++ RV +L K
Sbjct: 616 PYYYFQVGWNIFDSIIVTLSLVELGLANV--------QGLSVLRSFRLLRVFKLAKSWPT 667
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF-MHVKD---KGGLD---DVYNFK 1703
+ L+ + S+ AL N+ L+L +++FIFA+ GM F KD K + ++
Sbjct: 668 LNMLIKIIGSSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKDCVCKISTECELPRWHMN 727
Query: 1704 TFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVI 1763
F S +++F++ W I N C E G C + + +VI
Sbjct: 728 DFFHSFLIVFRI-LCGEW------IENMWAC----MEVAGAGMC------LVVFMMVMVI 770
Query: 1764 SFLIVINMYIAVILENYS 1781
L+V+N+++A++L ++S
Sbjct: 771 GNLVVLNLFLALLLSSFS 788
Score = 84.6 bits (200), Expect = 2e-14
Identities = 72/295 (24%), Positives = 139/295 (47%), Gaps = 40/295 (13%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNC-------ILMIMPTTPTV--ESTEVIFTGIYTFE 180
+R+ I+ H F FII IL++ I + T + E + +FT I+ E
Sbjct: 993 LRKTCFTIVEHDWFETFIIFMILLSSGALAFEDIYIERRRTVKIILEFADKVFTFIFVLE 1052
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVT-----MGI-DLGNLAALRTFRVLR 234
+K +A GF TY +AW WLDF ++ ++ ++ MG+ DLG + +LRT R LR
Sbjct: 1053 MVLKWVAYGFK----TYFTNAWCWLDFFIVDISLISLSANLMGLSDLGPIKSLRTLRALR 1108
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFP 294
L+ ++ G++ +V A+I ++ ++ +V+++ + +F++MG+ ++ G C+
Sbjct: 1109 PLRALSRFEGMRVVVNALIGAIPSIFNVLLVCLIFWLIFSIMGVNLFAGKF-YHCINTTT 1167
Query: 295 ED----GSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNP 350
++ N +D + E W +Y G GY+ L
Sbjct: 1168 QELFPISVVNNKSDCMAVQEATQEARWVNVKVNYDNVGK---------GYLSLLQIAT-- 1216
Query: 351 NYGYTSFDTFGWAFLSAFRLMTQDYWE-NLYQ-LFFVVIIFLGSFYLVNLILAIV 403
+ + +A + + + Q +E NLY ++FV+ I G+F+ +NL + ++
Sbjct: 1217 ---FKGWTAIMYAAVDSREVEEQPSYEINLYMYIYFVIFIIFGAFFTLNLFIGVI 1268
Score = 80.6 bits (190), Expect = 4e-13
Identities = 56/127 (44%), Positives = 69/127 (54%), Gaps = 16/127 (12%)
Query: 14 SLFRPFTRESLXXXXXXXXXXXXKQKELEKKRAEGEVRYXXXXXXXGPQPDATLEQGLPL 73
++FR FT +SL + KE KK AE R P P+ LE G L
Sbjct: 11 AMFRHFTPQSLAKIE--------RLKEETKKAAEVGPR----EEEEPPTPNPDLEAGKGL 58
Query: 74 PVRMQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNALWILDPFNPIRRV 133
P R+ G P EL STPLED+DPFY Q TFVVI+KG I+RF+A A +IL PF+ RV
Sbjct: 59 P-RIYGEPPAELLSTPLEDLDPFYKAQKTFVVITKGNTIYRFNAEPACYILSPFS---RV 114
Query: 134 AIYILVH 140
Y +H
Sbjct: 115 CFYRHLH 121
Score = 78.2 bits (184), Expect = 2e-12
Identities = 49/179 (27%), Positives = 87/179 (48%), Gaps = 13/179 (7%)
Query: 1202 QGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYM---DRI 1258
Q W + ++ + + + A+ I+L++L +A+E H P+ Q+ Y + + +
Sbjct: 544 QPWAVFKEWVHFVVMDPFVDLAITICIVLNTLFMAME-----HYPMTQEFDYMLSVGNLV 598
Query: 1259 FTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTL 1318
FT IF EM K +A+ YF W D IIV +SL+ G +Q +R+
Sbjct: 599 FTGIFAAEMFFKLIAMDPYYYFQVGWNIFDSIIVTLSLVEL-----GLANVQGLSVLRSF 653
Query: 1319 RALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCV 1377
R LR + + +++ + ++ ++ N+ LV I IFA++G+QLF Y CV
Sbjct: 654 RLLRVFKLAKSWPTLNMLIKIIGSSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKDCV 712
Score = 75.8 bits (178), Expect = 1e-11
Identities = 39/106 (36%), Positives = 61/106 (57%), Gaps = 4/106 (3%)
Query: 726 IEQAGRQSRASELNVSVYYFPTAEDDEDGPTFKEKLLDCLMKGIDFFCVWDCCWLWLEFQ 785
+E AG + R++ V+V E+ E+ + K + F W+CC W F+
Sbjct: 495 VEDAGLKQRSASA-VTVLTAAAVEELEEA---QRPCPPIWYKFANMFLKWNCCQPWAVFK 550
Query: 786 KYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGN 831
++V +V DPFV+L IT+CIV+NTLFMA++H+ M ++ D L GN
Sbjct: 551 EWVHFVVMDPFVDLAITICIVLNTLFMAMEHYPMTQEFDYMLSVGN 596
Score = 72.9 bits (171), Expect = 8e-11
Identities = 46/187 (24%), Positives = 94/187 (50%), Gaps = 14/187 (7%)
Query: 113 FRFSATNALW-ILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTE- 170
++F+ W P+ + ++++ P L I I++N + M M P + +
Sbjct: 531 YKFANMFLKWNCCQPWAVFKEWVHFVVMDPFVDLAITICIVLNTLFMAMEHYPMTQEFDY 590
Query: 171 ------VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGN 223
++FTGI+ E K++A + P+ Y + WN D +++ L+ V +G+ ++
Sbjct: 591 MLSVGNLVFTGIFAAEMFFKLIA----MDPYYYFQVGWNIFDSIIVTLSLVELGLANVQG 646
Query: 224 LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
L+ LR+FR+LR K P L ++ + SV L ++ ++ + +FA++G+Q++ G
Sbjct: 647 LSVLRSFRLLRVFKLAKSWPTLNMLIKIIGSSVGALGNLTLVLAIIVFIFAVVGMQLF-G 705
Query: 284 VLTQKCV 290
+ CV
Sbjct: 706 KSYKDCV 712
Score = 45.2 bits (102), Expect = 0.018
Identities = 41/167 (24%), Positives = 81/167 (48%), Gaps = 21/167 (12%)
Query: 128 NPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT---TPTVES----TEVIFTGIYTFE 180
N I+ + + F +FI+ I +N + M++ T +P E V F ++T E
Sbjct: 1329 NLIQGMVFDFISQQFFDIFIMVLICLNMVTMMVETDDQSPEKEDFLFKVNVAFIVVFTGE 1388
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV-TMGIDLGN--------LAALRTFR 231
+K++A L+ + + + WN DFVV+ L+ TM DL +R R
Sbjct: 1389 CMLKLIA----LRQY-FFTNGWNIFDFVVVILSIAGTMLSDLIEKYFVSPTLFRVIRLAR 1443
Query: 232 VLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGL 278
+ R L+ + G++T++ A++ S+ L ++ +L + +F++ G+
Sbjct: 1444 IGRILRLIKGARGIRTLLFALMMSLPALFNIGLLLFLIMFIFSIFGM 1490
Score = 38.3 bits (85), Expect = 2.1
Identities = 37/173 (21%), Positives = 76/173 (43%), Gaps = 8/173 (4%)
Query: 749 EDDEDGPTFKEKLLDCLMKGIDFFCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVN 808
E D+ P ++ L + I F +C + ++Y ++ F + + L I
Sbjct: 1362 ETDDQSPEKEDFLFKVNVAFIVVF-TGECMLKLIALRQYFFTNGWNIFDFVVVILSIAGT 1420
Query: 809 TLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCI 868
L ++ + + + + ++ R+ +L K + L+ + ++ AL N+ +L +
Sbjct: 1421 MLSDLIEKYFVSPTLFRVIRLARIGRILRLIKGARGIRTLLFALMMSLPALFNIGLLLFL 1480
Query: 869 IIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMIVFRV-LCGEW 920
I+FIF++ GM F YV + D +NF F S + +F++ G W
Sbjct: 1481 IMFIFSIFGMSNFA-----YVKKEAGID-DMFNFETFGSSIICLFQITTSGGW 1527
>UniRef50_P02719 Cluster: Sodium channel protein (Na(+) channel);
n=21; Euteleostomi|Rep: Sodium channel protein (Na(+)
channel) - Electrophorus electricus (Electric eel)
Length = 1820
Score = 765 bits (1891), Expect = 0.0
Identities = 376/755 (49%), Positives = 521/755 (69%), Gaps = 16/755 (2%)
Query: 1170 EDVVDDTPADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMIL 1229
E++ P C E+C +FPFL D + W LR + ++E+ YFET +I MIL
Sbjct: 952 EELESKDPEACFTEKCIWRFPFLDVDITQGKGKIWWNLRRTCYTIVEHDYFETFIIFMIL 1011
Query: 1230 LSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDF 1289
LSS LA ED+++ R +++ IL Y D++FT +F +EML+KW+A GF++YFT+AWCWLDF
Sbjct: 1012 LSSGVLAFEDIYIWRRRVIKVILEYADKVFTYVFIVEMLLKWVAYGFKRYFTDAWCWLDF 1071
Query: 1290 IIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFN 1349
+IV S++ ++L G + A K +RT+RALRPLRA+SR +GM+VVV AL+ AIPSI N
Sbjct: 1072 VIVGASIMGITSSLLGYEELGAIKNLRTIRALRPLRALSRFEGMKVVVRALLGAIPSIMN 1131
Query: 1350 VLLVCLIFWLIFAIMGVQLFAGKYFKCVDMN-HTTLSHEIIPDKNACTLENYT----WEN 1404
VLLVCL+FWLIF+IMGV LFAGK+++C++ L E + +++ C YT W N
Sbjct: 1132 VLLVCLMFWLIFSIMGVNLFAGKFYRCINTTTDEILPVEEVNNRSDCMALMYTNEVRWVN 1191
Query: 1405 SPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXX 1464
+N+D+ G YL L QV+TFKGW+ IM A+DSREV QPI E N+YMYLY
Sbjct: 1192 LKVNYDNAGMGYLSLLQVSTFKGWMDIMYAAVDSREVEDQPIYEINVYMYLYFVIFIVFG 1251
Query: 1465 XXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWR 1524
TLNLFIGVIIDNFN QK+K GG ++FMTE+QKKYYNAMKK+GSKK K IPRP
Sbjct: 1252 AFFTLNLFIGVIIDNFNRQKQKLGGE-DLFMTEEQKKYYNAMKKLGSKKAAKCIPRPSNV 1310
Query: 1525 PQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECL 1584
Q +V++IVT D+ IM I +NM+ M ++ QS+ +L +N+IF++IF+ ECL
Sbjct: 1311 VQGVVYDIVTQPFTDIFIMALICINMVAMMVESEDQSQVKKDILSQINVIFVIIFTVECL 1370
Query: 1585 LKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRL 1644
LK+ ALR ++F WN+FDF VV+ SI+ L+LSDIIEKYFVSPTL RV+R+A++ RVLRL
Sbjct: 1371 LKLLALRQYFFTVGWNVFDFAVVVISIIGLLLSDIIEKYFVSPTLFRVIRLARIARVLRL 1430
Query: 1645 VKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKT 1704
++ AKGIRTLLFAL MSLPALFNI LLLFL+MFIF+IFGMS F +VK +GG+DD++NF+T
Sbjct: 1431 IRAAKGIRTLLFALMMSLPALFNIGLLLFLIMFIFSIFGMSNFAYVKKQGGVDDIFNFET 1490
Query: 1705 FVQSMILLFQMSTSAGWDGVLDGIIN--EEECDLPDNERGSP---GNCGSATIGITYLLS 1759
F SMI LF+++TSAGWDG+L +N +CD PD E GNCG+ GIT+ S
Sbjct: 1491 FGNSMICLFEITTSAGWDGLLLPTLNTGPPDCD-PDVENPGTDVRGNCGNPGKGITFFCS 1549
Query: 1760 YLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQL 1819
Y+++SFL+V+NMYIA+ILEN+ A E+ + L +DD+ M+ E W +FD G+Q++ Y+ L
Sbjct: 1550 YIILSFLVVVNMYIAIILENFGVAQEESSDLLCEDDFVMFDETWHKFDVHGTQFLDYNDL 1609
Query: 1820 SDFLDVLEPPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTK----DFFARKGNPIE 1875
F++ L+ P++I PN++K+ MD+ + D + +D+L A+T+ D + +
Sbjct: 1610 PRFVNALQEPMRIPNPNRHKLAKMDMYVVMEDKISYLDVLLAVTQEVLGDTTEMEAMRLS 1669
Query: 1876 ETGDLEVGRPEEAGYEPVSSTLWRQREEYCARLIQ 1910
+ P +EPV +TL R+ EE+ + +IQ
Sbjct: 1670 IQAKFKKDNPSPTFFEPVVTTLRRKEEEWASVVIQ 1704
Score = 378 bits (930), Expect = e-103
Identities = 196/364 (53%), Positives = 248/364 (68%), Gaps = 22/364 (6%)
Query: 63 PDATLEQGLPLPVRMQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNALW 122
P LE G PLP+ + G P +L + PLED+DPFY Q TF+VISKG I RF+A AL+
Sbjct: 45 PRIDLEAGKPLPM-IYGDPPEDLLNIPLEDLDPFYKTQKTFIVISKGNIINRFNAERALY 103
Query: 123 ILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVES-TEVIFTGIYTFES 181
I PFNPIRR AI + V+ F+ FI+ TI NCI M + P E FTGIYTFE
Sbjct: 104 IFSPFNPIRRGAIRVFVNSAFNFFIMFTIFSNCIFMTISNPPAWSKIVEYTFTGIYTFEV 163
Query: 182 AVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAI 241
VKV++RGF + FT+LRD WNWLDF V+ + Y+T IDL N++ALRTFRVLRALKT+ I
Sbjct: 164 IVKVLSRGFCIGHFTFLRDPWNWLDFSVVTMTYITEFIDLRNVSALRTFRVLRALKTITI 223
Query: 242 VPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVK-----VFPED 296
PGLKTIV A+IES+K + DV+ILT+FSL+VF L G+Q++MG L KC++ V +
Sbjct: 224 FPGLKTIVRALIESMKQMGDVVILTVFSLAVFTLAGMQLFMGNLRHKCIRWPISNVTLDY 283
Query: 297 GSWGNLTDENWERFCQNETNWYGEGG--DYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGY 354
S N T + + + +NE N Y G D LCGN+S AG+C GY C++ G NPNYGY
Sbjct: 284 ESAYNTTFD-FTAYIENEENQYFLDGALDALLCGNNSDAGKCPEGYTCMKA-GRNPNYGY 341
Query: 355 TSFDTFGWAFLSAFRLMTQDYWENLYQL-----------FFVVIIFLGSFYLVNLILAIV 403
T++D F W FL FRLM QDYWENLYQ+ FF+++IFLGSFYL+NLILA+V
Sbjct: 342 TNYDNFAWTFLCLFRLMLQDYWENLYQMTLRAAGKSYMVFFIMVIFLGSFYLINLILAVV 401
Query: 404 AMSY 407
AM+Y
Sbjct: 402 AMAY 405
Score = 176 bits (429), Expect = 4e-42
Identities = 89/192 (46%), Positives = 118/192 (61%), Gaps = 4/192 (2%)
Query: 805 IVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTF 864
I+V+ + L NM + M L+S LR+FKLAKSWPTLN+LI I+ ++GALGNLT
Sbjct: 636 IIVSLSLLELGLSNM-QGMS-VLRSLRLLRIFKLAKSWPTLNILIKIICNSVGALGNLTI 693
Query: 865 VLCIIIFIFAVMGMQLFGKNYVDYVDRFPDG-DLPRWNFTDFMHSFMIVFRVLCGEWIES 923
VL II+FIFA++G QLFGKNY +YV + D +LPRW+ DF HSF+IVFR LCGEWIE+
Sbjct: 694 VLAIIVFIFALVGFQLFGKNYKEYVCKISDDCELPRWHMNDFFHSFLIVFRALCGEWIET 753
Query: 924 MWDCMLVGDV-SCIPFFLATVVIXXXXXXXXXXXXXXXXXXXXXXXTPTADQDTNKIAEA 982
MWDCM VG V C+ ++ ++I + D + N + A
Sbjct: 754 MWDCMEVGGVPMCLAVYMMVIIIGNLVMLNLFLALLLSSFSSDNLSSIEEDDEVNSLQVA 813
Query: 983 FNRISRFIDWIK 994
RISR +W+K
Sbjct: 814 SERISRAKNWVK 825
Score = 97.5 bits (232), Expect = 3e-18
Identities = 53/157 (33%), Positives = 94/157 (59%), Gaps = 9/157 (5%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL- 1590
++ D D+ I L I LN L M+++H+ +E+F ++L N++F IF++E +LKI AL
Sbjct: 562 VMMDPFTDLFITLCIILNTLFMSIEHHPMNESFQSLLSAGNLVFTTIFAAEMVLKIIALD 621
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
Y+YF + WN+FD ++V S+L L LS++ + V+R ++ R+ +L K
Sbjct: 622 PYYYFQQTWNIFDSIIVSLSLLELGLSNM--------QGMSVLRSLRLLRIFKLAKSWPT 673
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+ L+ + S+ AL N+ ++L +++FIFA+ G F
Sbjct: 674 LNILIKIICNSVGALGNLTIVLAIIVFIFALVGFQLF 710
Score = 79.8 bits (188), Expect = 7e-13
Identities = 71/294 (24%), Positives = 135/294 (45%), Gaps = 39/294 (13%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMPTT---------PTVESTEVIFTGIYTFE 180
+RR I+ H F FII IL++ ++ +E + +FT ++ E
Sbjct: 989 LRRTCYTIVEHDYFETFIIFMILLSSGVLAFEDIYIWRRRVIKVILEYADKVFTYVFIVE 1048
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAY--VTMGI----DLGNLAALRTFRVLR 234
+K +A GF Y DAW WLDFV++ + +T + +LG + LRT R LR
Sbjct: 1049 MLLKWVAYGFK----RYFTDAWCWLDFVIVGASIMGITSSLLGYEELGAIKNLRTIRALR 1104
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFP 294
L+ ++ G+K +V A++ ++ ++ +V+++ + +F++MG+ ++ G +C+
Sbjct: 1105 PLRALSRFEGMKVVVRALLGAIPSIMNVLLVCLMFWLIFSIMGVNLFAGKF-YRCINTTT 1163
Query: 295 ED---GSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPN 351
++ N + NE W L N AG GY+ L
Sbjct: 1164 DEILPVEEVNNRSDCMALMYTNEVRWVN------LKVNYDNAGM---GYLSLLQVST--- 1211
Query: 352 YGYTSFDTFGWAFLSAFRLMTQDYWE-NLYQ-LFFVVIIFLGSFYLVNLILAIV 403
+ + +A + + + Q +E N+Y L+FV+ I G+F+ +NL + ++
Sbjct: 1212 --FKGWMDIMYAAVDSREVEDQPIYEINVYMYLYFVIFIVFGAFFTLNLFIGVI 1263
Score = 76.2 bits (179), Expect = 9e-12
Identities = 48/172 (27%), Positives = 87/172 (50%), Gaps = 8/172 (4%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W L+ ++ + + + + I+L++L +++E H P Q +L + +FT IF
Sbjct: 552 WVFLKKWVHFVMMDPFTDLFITLCIILNTLFMSIE--HHPMNESFQSLLSAGNLVFTTIF 609
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRP 1323
EM++K +AL YF W D IIV +SL+ G +Q +R+LR LR
Sbjct: 610 AAEMVLKIIALDPYYYFQQTWNIFDSIIVSLSLLEL-----GLSNMQGMSVLRSLRLLRI 664
Query: 1324 LRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK 1375
+ + +++ + ++ ++ N+ +V I IFA++G QLF GK +K
Sbjct: 665 FKLAKSWPTLNILIKIICNSVGALGNLTIVLAIIVFIFALVGFQLF-GKNYK 715
Score = 74.9 bits (176), Expect = 2e-11
Identities = 28/61 (45%), Positives = 43/61 (70%)
Query: 771 FFCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSG 830
F W+CC W+ +K+V ++ DPF +LFITLCI++NTLFM+++HH M++ L +G
Sbjct: 542 FVFKWNCCGPWVFLKKWVHFVMMDPFTDLFITLCIILNTLFMSIEHHPMNESFQSLLSAG 601
Query: 831 N 831
N
Sbjct: 602 N 602
Score = 74.9 bits (176), Expect = 2e-11
Identities = 42/164 (25%), Positives = 88/164 (53%), Gaps = 12/164 (7%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTE-------VIFTGIYT 178
P+ +++ ++++ P LFI I++N + M + P ES + ++FT I+
Sbjct: 551 PWVFLKKWVHFVMMDPFTDLFITLCIILNTLFMSIEHHPMNESFQSLLSAGNLVFTTIFA 610
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGNLAALRTFRVLRALK 237
E +K++A L P+ Y + WN D ++++L+ + +G+ ++ ++ LR+ R+LR K
Sbjct: 611 AEMVLKIIA----LDPYYYFQQTWNIFDSIIVSLSLLELGLSNMQGMSVLRSLRLLRIFK 666
Query: 238 TVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
P L ++ + SV L ++ I+ + +FAL+G Q++
Sbjct: 667 LAKSWPTLNILIKIICNSVGALGNLTIVLAIIVFIFALVGFQLF 710
Score = 64.5 bits (150), Expect = 3e-08
Identities = 39/137 (28%), Positives = 77/137 (56%), Gaps = 15/137 (10%)
Query: 1259 FTVIFFIEMLIKWLALGFQ-KYFT---NAWCWLDF-IIVMVSLINFVAALCGAGGIQAFK 1313
FT I+ E+++K L+ GF +FT + W WLDF ++ M + F+ ++
Sbjct: 155 FTGIYTFEVIVKVLSRGFCIGHFTFLRDPWNWLDFSVVTMTYITEFI-------DLRNVS 207
Query: 1314 TMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
+RT R LR L+ ++ G++ +V AL++++ + +V+++ + +F + G+QLF G
Sbjct: 208 ALRTFRVLRALKTITIFPGLKTIVRALIESMKQMGDVVILTVFSLAVFTLAGMQLFMGNL 267
Query: 1374 -FKCV--DMNHTTLSHE 1387
KC+ +++ TL +E
Sbjct: 268 RHKCIRWPISNVTLDYE 284
Score = 50.0 bits (114), Expect = 6e-04
Identities = 40/180 (22%), Positives = 85/180 (47%), Gaps = 25/180 (13%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT-------TPTVESTEVIFTGIYT 178
P N ++ V I+ P +FI+ I +N + M++ + + VIF I+T
Sbjct: 1307 PSNVVQGVVYDIVTQPFTDIFIMALICINMVAMMVESEDQSQVKKDILSQINVIFVIIFT 1366
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNL-----------AAL 227
E +K++A L+ + + WN DF V+ ++ + G+ L ++ +
Sbjct: 1367 VECLLKLLA----LRQY-FFTVGWNVFDFAVVVISII--GLLLSDIIEKYFVSPTLFRVI 1419
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQ 287
R R+ R L+ + G++T++ A++ S+ L ++ +L + +F++ G+ + V Q
Sbjct: 1420 RLARIARVLRLIRAAKGIRTLLFALMMSLPALFNIGLLLFLIMFIFSIFGMSNFAYVKKQ 1479
Score = 48.8 bits (111), Expect = 0.001
Identities = 38/162 (23%), Positives = 78/162 (48%), Gaps = 20/162 (12%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKI---- 1587
+ + F+ IM I N + MT+ + +S +++Y F I++ E ++K+
Sbjct: 118 VFVNSAFNFFIMFTIFSNCIFMTISN---PPAWSKIVEYT---FTGIYTFEVIVKVLSRG 171
Query: 1588 FALRYHYFV-EPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVK 1646
F + + F+ +PWN DF VV + ++ F+ + +R +V R L+ +
Sbjct: 172 FCIGHFTFLRDPWNWLDFSVVTMTYIT---------EFIDLRNVSALRTFRVLRALKTIT 222
Query: 1647 GAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
G++T++ AL S+ + ++ +L + +F + GM FM
Sbjct: 223 IFPGLKTIVRALIESMKQMGDVVILTVFSLAVFTLAGMQLFM 264
Score = 40.3 bits (90), Expect = 0.52
Identities = 37/189 (19%), Positives = 80/189 (42%), Gaps = 7/189 (3%)
Query: 750 DDEDGPTFKEKLLDCLMKGIDFFCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNT 809
+ ED K+ +L + +C L ++Y + ++ F + + I+
Sbjct: 1342 ESEDQSQVKKDILSQINVIFVIIFTVECLLKLLALRQYFFTVGWNVFDFAVVVISIIGLL 1401
Query: 810 LFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCII 869
L ++ + + + + ++ RV +L ++ + L+ + ++ AL N+ +L +I
Sbjct: 1402 LSDIIEKYFVSPTLFRVIRLARIARVLRLIRAAKGIRTLLFALMMSLPALFNIGLLLFLI 1461
Query: 870 IFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
+FIF++ GM F YV + G +NF F +S + +F + W + +
Sbjct: 1462 MFIFSIFGMSNFA-----YVKK-QGGVDDIFNFETFGNSMICLFEITTSAGWDGLLLPTL 1515
Query: 929 LVGDVSCIP 937
G C P
Sbjct: 1516 NTGPPDCDP 1524
>UniRef50_Q4T100 Cluster: Chromosome undetermined SCAF10773, whole
genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome undetermined SCAF10773, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1469
Score = 763 bits (1886), Expect = 0.0
Identities = 372/663 (56%), Positives = 488/663 (73%), Gaps = 16/663 (2%)
Query: 1168 ADEDVVDDTPADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITM 1227
ADED V P DC E CY + P L D + W +R F ++EN YFE+ ++ M
Sbjct: 659 ADEDNVSKMPMDCWSENCYSRCPSLDIDTSQGKGKVWCNIRRACFIIVENNYFESFIVFM 718
Query: 1228 ILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWL 1287
ILLSS ALA ED++L +++ IL Y D++FT +F +EM++KW A GF+ YF+NAWCWL
Sbjct: 719 ILLSSGALAFEDIYLEKHQLIKTILEYADKVFTYVFVVEMVLKWFAYGFKSYFSNAWCWL 778
Query: 1288 DFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSI 1347
DF+IV VSL++ A + G + A K++RTLRALRPLRA+SR +GMRVVVNALV A+PSI
Sbjct: 779 DFLIVDVSLVSLTANILGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALVGAVPSI 838
Query: 1348 FNVLLVCLIFWLIFAIMGVQLFAGKYFKCV-DMNHTTLSHEIIPDKNACTL---ENYT-- 1401
FNVLLVCLIFWLIF+IMGV LFAGK+ C + + +I+ +K C N+T
Sbjct: 839 FNVLLVCLIFWLIFSIMGVNLFAGKFSYCFNETSQEQFDKKIVNNKTECIALIEANFTEV 898
Query: 1402 -WENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXX 1460
W+N +N+D+VG YL L QVATFKGW++IM A+DSR+V QPI E NIYMYLY
Sbjct: 899 RWKNLKVNYDNVGIGYLSLLQVATFKGWMEIMYAAVDSRDVESQPIYEVNIYMYLYFVIF 958
Query: 1461 XXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPR 1520
TLNLFIGVIIDNFN+QK K G ++FMTE+QKKYYNAMKK+GSKKP K +PR
Sbjct: 959 IIFGSFFTLNLFIGVIIDNFNQQKAKICGQ-DIFMTEEQKKYYNAMKKLGSKKPQKPVPR 1017
Query: 1521 PRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFS 1580
P Q +VF++VT + FD+ IM+ I LNM+TM ++ +Q++ +L ++N+IFIVIF+
Sbjct: 1018 PENALQGLVFDLVTKQIFDVFIMVLICLNMVTMMVETDEQTKEKEDILYWINVIFIVIFT 1077
Query: 1581 SECLLKIFALRYHYFVEPWNLFDFVVVMFSIL---SLVLSDIIEKYFVSPTLLRVVRVAK 1637
+EC+LK ALR HYF WN+FDFVVV+ SIL L+L+DIIEKYFVSPTL RV+R+A+
Sbjct: 1078 TECILKTIALRRHYFSIGWNVFDFVVVILSILGVSGLLLADIIEKYFVSPTLFRVIRLAR 1137
Query: 1638 VGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLD 1697
+GRVLRL++GAKGIRTLLFAL MSLPALFNI LLLFL+MFIF+IFGMS F +VK + +D
Sbjct: 1138 IGRVLRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLIMFIFSIFGMSNFAYVKKEAMID 1197
Query: 1698 DVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINE-EECDLPDNERGSP---GNCGSATIG 1753
D++NF+TF SMI LF ++TSAGWDG+L I+N+ +CD PD E GNCGS IG
Sbjct: 1198 DMFNFETFGNSMICLFMITTSAGWDGLLSPIMNKPPDCD-PDLENPGTTVRGNCGSPAIG 1256
Query: 1754 ITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQY 1813
I + +Y+++SFL+V+NMYIA+ILEN++ ATE+ + L +DD+DM+YE W++FDPD +Q+
Sbjct: 1257 IVFFSTYIIMSFLVVVNMYIAIILENFNVATEESSDPLCEDDFDMFYETWEKFDPDATQF 1316
Query: 1814 IRY 1816
I+Y
Sbjct: 1317 IQY 1319
Score = 281 bits (688), Expect = 2e-73
Identities = 143/272 (52%), Positives = 189/272 (69%), Gaps = 9/272 (3%)
Query: 62 QPDATLEQGLPLPVRMQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNAL 121
+P + LE G PLP + G P EL + PLED+DPFY +Q TF+V+SKG I RF+A ++L
Sbjct: 1 EPASDLEAGKPLPF-IYGEPPHELLNVPLEDMDPFYQSQKTFIVLSKGNVIHRFNAESSL 59
Query: 122 WILDPFNPIRRVAIYILVHP---LFSLFIITTILVNCILMIMPTTPTVEST-EVIFTGIY 177
++L PFN +R AI ILVH LFSLFI+ TIL NC+ M + P T E +FT IY
Sbjct: 60 YLLSPFNSMRIFAIKILVHSYKTLFSLFIMATILTNCVFMTLSDPPAWSKTVEYVFTFIY 119
Query: 178 TFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALK 237
TFE+ +KV++RGF + FT+L+D WNWLDF+VI++AY+T +DLGN++ LRTFRVLRALK
Sbjct: 120 TFEATIKVVSRGFCVGQFTFLKDPWNWLDFMVISMAYLTELVDLGNVSVLRTFRVLRALK 179
Query: 238 TVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDG 297
T+ ++PGLKTIVGA+I+SVK L D ++LT+F LSVFAL+GLQ++MG L QKCV + P
Sbjct: 180 TITVIPGLKTIVGALIQSVKKLADAMVLTVFCLSVFALIGLQLFMGNLRQKCVLIPPVGL 239
Query: 298 SWGNLTDENWER----FCQNETNWYGEGGDYP 325
S E W+ Q W G G +P
Sbjct: 240 SRELHLSEGWQESKLWLHQLRLLWLGILGSFP 271
Score = 165 bits (400), Expect = 1e-38
Identities = 76/121 (62%), Positives = 94/121 (77%), Gaps = 2/121 (1%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+S +RVFKLAKSWPTLN+LI I+G ++GALGNLT VL II+FIFAV+GMQLFGKNY
Sbjct: 515 LRSFRLMRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKNYK 574
Query: 887 DYVDRF-PDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLV-GDVSCIPFFLATVV 944
D V R D LPRW+ DF H+F+I+FRVLCGEWI++MWDCM V G C+ ++ +V
Sbjct: 575 DCVCRISEDCKLPRWHMNDFFHAFLIIFRVLCGEWIDTMWDCMEVSGQTMCLIVYMMVLV 634
Query: 945 I 945
I
Sbjct: 635 I 635
Score = 92.3 bits (219), Expect = 1e-16
Identities = 55/157 (35%), Positives = 88/157 (56%), Gaps = 9/157 (5%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL- 1590
IV D D+ I + I LN + M ++HY S F +L N++F IF+ E +LKI A+
Sbjct: 421 IVMDPFVDLGITICIILNTIFMAMEHYPMSADFEELLSVGNLVFTGIFTCEMVLKILAMD 480
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
Y YF WN+FD ++V S++ L L+++ L V+R ++ RV +L K
Sbjct: 481 PYFYFQVGWNIFDSIIVTMSLVELGLANV--------QGLSVLRSFRLMRVFKLAKSWPT 532
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+ L+ + S+ AL N+ L+L +++FIFA+ GM F
Sbjct: 533 LNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLF 569
Score = 79.4 bits (187), Expect = 9e-13
Identities = 46/174 (26%), Positives = 87/174 (50%), Gaps = 7/174 (4%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W L+ ++ + + + + I+L+++ +A+E H P +++L + +FT IF
Sbjct: 411 WRHLKRCLSAIVMDPFVDLGITICIILNTIFMAME--HYPMSADFEELLSVGNLVFTGIF 468
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRP 1323
EM++K LA+ YF W D IIV +SL+ G +Q +R+ R +R
Sbjct: 469 TCEMVLKILAMDPYFYFQVGWNIFDSIIVTMSLVEL-----GLANVQGLSVLRSFRLMRV 523
Query: 1324 LRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCV 1377
+ + +++ + ++ ++ N+ LV I IFA++G+QLF Y CV
Sbjct: 524 FKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKNYKDCV 577
Score = 78.2 bits (184), Expect = 2e-12
Identities = 68/291 (23%), Positives = 137/291 (47%), Gaps = 31/291 (10%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMPTT---------PTVESTEVIFTGIYTFE 180
IRR I+ + F FI+ IL++ + +E + +FT ++ E
Sbjct: 698 IRRACFIIVENNYFESFIVFMILLSSGALAFEDIYLEKHQLIKTILEYADKVFTYVFVVE 757
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI------DLGNLAALRTFRVLR 234
+K A GF +Y +AW WLDF+++ ++ V++ +LG + +LRT R LR
Sbjct: 758 MVLKWFAYGFK----SYFSNAWCWLDFLIVDVSLVSLTANILGYSELGAIKSLRTLRALR 813
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFP 294
L+ ++ G++ +V A++ +V ++ +V+++ + +F++MG+ ++ G + C
Sbjct: 814 PLRALSRFEGMRVVVNALVGAVPSIFNVLLVCLIFWLIFSIMGVNLFAGKFSY-CFNETS 872
Query: 295 EDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGY 354
++ + + E E N + E L N G GY+ L +
Sbjct: 873 QEQFDKKIVNNKTECIALIEAN-FTEVRWKNLKVNYDNVG---IGYLSLLQVAT-----F 923
Query: 355 TSFDTFGWAFLSAFRLMTQDYWE-NLYQ-LFFVVIIFLGSFYLVNLILAIV 403
+ +A + + + +Q +E N+Y L+FV+ I GSF+ +NL + ++
Sbjct: 924 KGWMEIMYAAVDSRDVESQPIYEVNIYMYLYFVIFIIFGSFFTLNLFIGVI 974
Score = 77.4 bits (182), Expect = 4e-12
Identities = 48/175 (27%), Positives = 91/175 (52%), Gaps = 13/175 (7%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTE-------VIFTGIYTFESA 182
++R I++ P L I I++N I M M P E ++FTGI+T E
Sbjct: 414 LKRCLSAIVMDPFVDLGITICIILNTIFMAMEHYPMSADFEELLSVGNLVFTGIFTCEMV 473
Query: 183 VKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGNLAALRTFRVLRALKTVAI 241
+K++A + P+ Y + WN D +++ ++ V +G+ ++ L+ LR+FR++R K
Sbjct: 474 LKILA----MDPYFYFQVGWNIFDSIIVTMSLVELGLANVQGLSVLRSFRLMRVFKLAKS 529
Query: 242 VPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPED 296
P L ++ + SV L ++ ++ + +FA++G+Q++ G + CV ED
Sbjct: 530 WPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLF-GKNYKDCVCRISED 583
Score = 73.3 bits (172), Expect = 6e-11
Identities = 28/68 (41%), Positives = 44/68 (64%)
Query: 764 CLMKGIDFFCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDM 823
C + F WDCC W ++ ++ +V DPFV+L IT+CI++NT+FMA++H+ M D
Sbjct: 394 CWYAFANVFLKWDCCSCWRHLKRCLSAIVMDPFVDLGITICIILNTIFMAMEHYPMSADF 453
Query: 824 DKALKSGN 831
++ L GN
Sbjct: 454 EELLSVGN 461
Score = 72.1 bits (169), Expect = 1e-10
Identities = 49/193 (25%), Positives = 99/193 (51%), Gaps = 22/193 (11%)
Query: 1204 WGTLRLKTFKLIENTY---FETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFT 1260
+ ++R+ K++ ++Y F ++ IL + + + L D P + Y +FT
Sbjct: 65 FNSMRIFAIKILVHSYKTLFSLFIMATILTNCVFMTLSDP-----PAWSKTVEY---VFT 116
Query: 1261 VIFFIEMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMR 1316
I+ E IK ++ GF + + W WLDF+++ ++ ++ L G + +T R
Sbjct: 117 FIYTFEATIKVVSRGFCVGQFTFLKDPWNWLDFMVISMA---YLTELVDLGNVSVLRTFR 173
Query: 1317 TLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FK 1375
LRAL+ + + G++ +V AL+Q++ + + +++ + +FA++G+QLF G K
Sbjct: 174 VLRALKTITVIP---GLKTIVGALIQSVKKLADAMVLTVFCLSVFALIGLQLFMGNLRQK 230
Query: 1376 CVDMNHTTLSHEI 1388
CV + LS E+
Sbjct: 231 CVLIPPVGLSREL 243
Score = 56.4 bits (130), Expect = 7e-06
Identities = 62/264 (23%), Positives = 126/264 (47%), Gaps = 37/264 (14%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL-----RY 1592
F + IM I N + MTL +S ++Y +F I++ E +K+ + ++
Sbjct: 84 FSLFIMATILTNCVFMTLS---DPPAWSKTVEY---VFTFIYTFEATIKVVSRGFCVGQF 137
Query: 1593 HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIR 1652
+ +PWN DF+V+ + L+ ++++ VS V+R +V R L+ + G++
Sbjct: 138 TFLKDPWNWLDFMVISMAYLT----ELVDLGNVS-----VLRTFRVLRALKTITVIPGLK 188
Query: 1653 TLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM-HVKDK-------GGLDDVYNFKT 1704
T++ AL S+ L + +L + +FA+ G+ FM +++ K G +++ +
Sbjct: 189 TIVGALIQSVKKLADAMVLTVFCLSVFALIGLQLFMGNLRQKCVLIPPVGLSRELHLSEG 248
Query: 1705 FVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVIS 1764
+ +S + L Q+ W G+L G ++ L S G TY++ ++V+
Sbjct: 249 WQESKLWLHQLRLL--WLGIL-GSFPADDARLLGK---SFPKLTLRAAGKTYMIFFVVVI 302
Query: 1765 FL---IVINMYIAVILENYSQATE 1785
FL +IN+ +AV+ Y++ +
Sbjct: 303 FLGSFYLINLILAVVAMAYAEQNQ 326
Score = 53.2 bits (122), Expect = 7e-05
Identities = 22/28 (78%), Positives = 27/28 (96%)
Query: 380 YQLFFVVIIFLGSFYLVNLILAIVAMSY 407
Y +FFVV+IFLGSFYL+NLILA+VAM+Y
Sbjct: 294 YMIFFVVVIFLGSFYLINLILAVVAMAY 321
Score = 48.0 bits (109), Expect = 0.003
Identities = 44/195 (22%), Positives = 91/195 (46%), Gaps = 24/195 (12%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTE-------VIFTGIYT 178
P N ++ + ++ +F +FI+ I +N + M++ T + E VIF I+T
Sbjct: 1018 PENALQGLVFDLVTKQIFDVFIMVLICLNMVTMMVETDEQTKEKEDILYWINVIFIVIFT 1077
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV-TMGIDLGNL-----------AA 226
E +K +A L+ Y WN DFVV+ L+ + G+ L ++
Sbjct: 1078 TECILKTIA----LRRH-YFSIGWNVFDFVVVILSILGVSGLLLADIIEKYFVSPTLFRV 1132
Query: 227 LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLT 286
+R R+ R L+ + G++T++ A++ S+ L ++ +L + +F++ G+ + V
Sbjct: 1133 IRLARIGRVLRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLIMFIFSIFGMSNFAYVKK 1192
Query: 287 QKCVKVFPEDGSWGN 301
+ + ++GN
Sbjct: 1193 EAMIDDMFNFETFGN 1207
>UniRef50_Q9UI33 Cluster: Sodium channel protein type 11 subunit
alpha; n=14; Eutheria|Rep: Sodium channel protein type 11
subunit alpha - Homo sapiens (Human)
Length = 1791
Score = 756 bits (1870), Expect = 0.0
Identities = 372/748 (49%), Positives = 518/748 (69%), Gaps = 21/748 (2%)
Query: 1170 EDVVDDTPADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMIL 1229
E V P C P+ FP + D P W W LR ++++++++FE+ +I +IL
Sbjct: 1008 EMVPKKQPERCLPKGFGCCFPCCSVDKRKPPWVIWWNLRKTCYQIVKHSWFESFIIFVIL 1067
Query: 1230 LSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDF 1289
LSS AL EDVHL ++P +Q++L D IFT IF +EM++KW+A GF KYFT+AWC LDF
Sbjct: 1068 LSSGALIFEDVHLENQPKIQELLNCTDIIFTHIFILEMVLKWVAFGFGKYFTSAWCCLDF 1127
Query: 1290 IIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFN 1349
IIV+VS+ + + K+ RTLRALRPLRA+S+ +GM+VVVNAL+ AIP+I N
Sbjct: 1128 IIVIVSVTTLI-------NLMELKSFRTLRALRPLRALSQFEGMKVVVNALIGAIPAILN 1180
Query: 1350 VLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNF 1409
VLLVCLIFWL+F I+GV F+GK+ KC++ + +++ II +K+ C N++W N +NF
Sbjct: 1181 VLLVCLIFWLVFCILGVYFFSGKFGKCINGTDSVINYTIITNKSQCESGNFSWINQKVNF 1240
Query: 1410 DHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTL 1469
D+VG AYL L QVATFKGW+ I+ A+DS E +QP E+N Y+Y TL
Sbjct: 1241 DNVGNAYLALLQVATFKGWMDIIYAAVDSTEKEQQPEFESNSLGYIYFVVFIIFGSFFTL 1300
Query: 1470 NLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIV 1529
NLFIGVIIDNFN+Q+KK GG ++FMTE+QKKYYNAMKK+GSKKP K IPRP + Q +V
Sbjct: 1301 NLFIGVIIDNFNQQQKKLGGQ-DIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKCQGLV 1359
Query: 1530 FEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFA 1589
F+IVT + FD+II+ I LNM++M + Y Q + ++LD+LN +F+VIF+ ECL+KIFA
Sbjct: 1360 FDIVTSQIFDIIIISLIILNMISMMAESYNQPKAMKSILDHLNWVFVVIFTLECLIKIFA 1419
Query: 1590 LRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFV--SPTLLRVVRVAKVGRVLRLVKG 1647
LR +YF WNLFD VVV+ SI+S ++S + + + PTL R+VR+A++GR+LRLV+
Sbjct: 1420 LRQYYFTNGWNLFDCVVVLLSIVSTMISTLENQEHIPFPPTLFRIVRLARIGRILRLVRA 1479
Query: 1648 AKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQ 1707
A+GIRTLLFAL MSLP+LFNI LLLFL+MFI+AI GM++F V + G+DD++NFKTF
Sbjct: 1480 ARGIRTLLFALMMSLPSLFNIGLLLFLIMFIYAILGMNWFSKVNPESGIDDIFNFKTFAS 1539
Query: 1708 SMILLFQMSTSAGWDGVLDGII-NEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFL 1766
SM+ LFQ+STSAGWD +L ++ ++E C+ S NC I +Y +SY++ISFL
Sbjct: 1540 SMLCLFQISTSAGWDSLLSPMLRSKESCN------SSSENCHLPGIATSYFVSYIIISFL 1593
Query: 1767 IVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVL 1826
IV+NMYIAVILEN++ ATE+ ++ L +DD+D++YE+W++FDP+ +Q+I+Y LSDF D L
Sbjct: 1594 IVVNMYIAVILENFNTATEESEDPLGEDDFDIFYEVWEKFDPEATQFIKYSALSDFADAL 1653
Query: 1827 EPPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTKDFFARKGNPIEETGDLE----V 1882
PL++ KPNKY+ + MD+P+ D + C+DIL A T +E
Sbjct: 1654 PEPLRVAKPNKYQFLVMDLPMVSEDRLHCMDILFAFTARVLGGSDGLDSMKAMMEEKFME 1713
Query: 1883 GRPEEAGYEPVSSTLWRQREEYCARLIQ 1910
P + YEP+ +T R+ EE A +IQ
Sbjct: 1714 ANPLKKLYEPIVTTTKRKEEERGAAIIQ 1741
Score = 326 bits (800), Expect = 5e-87
Identities = 185/418 (44%), Positives = 252/418 (60%), Gaps = 41/418 (9%)
Query: 8 ISEEERSLFRPFTRESLXXXXXXXXXXXXKQKELEKKRAEGEVRYXXXXXXXGPQPDATL 67
I +ER+ FRPFT +SL K+K K GEV P+P L
Sbjct: 9 IFPDERN-FRPFTSDSLAAIEKRIAIQKEKKKS---KDQTGEVPQ--------PRPQLDL 56
Query: 68 EQGLPLPVRMQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNALWILDPF 127
+ LP ++ G P EL PLED+DPFY N TF+V+++ + I+RFSA +AL+I PF
Sbjct: 57 KASRKLP-KLYGDIPRELIGKPLEDLDPFYRNHKTFMVLNRKRTIYRFSAKHALFIFGPF 115
Query: 128 NPIRRVAIYILVHPLFSLFIITTILVNCILMIM-----PTTPTVESTEVIFTGIYTFESA 182
N IR +AI + VH LFS+FII T+++NC+ M + + E +FTGIY FE+
Sbjct: 116 NSIRSLAIRVSVHSLFSMFIIGTVIINCVFMATGPAKNSNSNNTDIAECVFTGIYIFEAL 175
Query: 183 VKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM--GIDLGNLAALRTFRVLRALKTVA 240
+K++ARGFIL F++LRD WNWLD +VI +A V+ GI + L LRTFRV RALK ++
Sbjct: 176 IKILARGFILDEFSFLRDPWNWLDSIVIGIAIVSYIPGITI-KLLPLRTFRVFRALKAIS 234
Query: 241 IVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWG 300
+V LK IVGA++ SVK L +VIILT F LS+FAL+G Q++MG L KC+ ++ S
Sbjct: 235 VVSRLKVIVGALLRSVKKLVNVIILTFFCLSIFALVGQQLFMGSLNLKCISRDCKNIS-- 292
Query: 301 NLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTF 360
E ++ + + N ++ +CG G C Y C + NP+Y YT+FD F
Sbjct: 293 --NPEAYDHCFEKKEN----SPEFKMCGIWMGNSACSIQYEC-KHTKINPDYNYTNFDNF 345
Query: 361 GWAFLSAFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
GW+FL+ FRLMTQD WE LYQ FF+V+IFLGSFYL+NL LA+V M+Y
Sbjct: 346 GWSFLAMFRLMTQDSWEKLYQQTLRTTGLYSVFFFIVVIFLGSFYLINLTLAVVTMAY 403
Score = 134 bits (324), Expect = 2e-29
Identities = 68/129 (52%), Positives = 88/129 (68%), Gaps = 10/129 (7%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+S LRVFKLAKSWPTLN LI I+G ++GALG+LT VL I+IFIF+V+GMQLFG+++
Sbjct: 669 LRSFRVLRVFKLAKSWPTLNTLIKIIGNSVGALGSLTVVLVIVIFIFSVVGMQLFGRSFN 728
Query: 887 DYVDR---FPDGD----LPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVS---CI 936
P G L W+ DF HSF++VFR+LCGEWIE+MW+CM + S C+
Sbjct: 729 SQKSPKLCNPTGPTVSCLRHWHMGDFWHSFLVVFRILCGEWIENMWECMQEANASSSLCV 788
Query: 937 PFFLATVVI 945
F+ VI
Sbjct: 789 IVFILITVI 797
Score = 94.7 bits (225), Expect = 2e-17
Identities = 75/266 (28%), Positives = 137/266 (51%), Gaps = 16/266 (6%)
Query: 1521 PRWR-PQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIF 1579
P+W + ++ ++TD ++ I + I +N + + ++H++ +F +L+ N++F IF
Sbjct: 561 PQWLCVKKVLRTVMTDPFTELAITICIIINTVFLAMEHHKMEASFEKMLNIGNLVFTSIF 620
Query: 1580 SSECLLKIFAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKV 1638
+E LKI AL YHYF WN+FD +V + S V++ +++K S LR RV
Sbjct: 621 IAEMCLKIIALDPYHYFRRGWNIFDSIVALLSFAD-VMNCVLQKR--SWPFLRSFRVL-- 675
Query: 1639 GRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDD 1698
RV +L K + TL+ + S+ AL ++ ++L +V+FIF++ GM F +
Sbjct: 676 -RVFKLAKSWPTLNTLIKIIGNSVGALGSLTVVLVIVIFIFSVVGMQLFGRSFNSQKSPK 734
Query: 1699 VYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEEC-DLPDN--ERGSPGNCGSATIGIT 1755
+ N S + + M W L ++ C + +N E N S+ I
Sbjct: 735 LCNPTGPTVSCLRHWHMGDF--WHSFL--VVFRILCGEWIENMWECMQEANASSSLCVIV 790
Query: 1756 YLLSYLVISFLIVINMYIAVILENYS 1781
++L VI L+V+N++IA++L ++S
Sbjct: 791 FIL-ITVIGKLVVLNLFIALLLNSFS 815
Score = 81.4 bits (192), Expect = 2e-13
Identities = 66/266 (24%), Positives = 126/266 (47%), Gaps = 46/266 (17%)
Query: 1258 IFTVIFFIEMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFK 1313
+FT I+ E LIK LA GF + + W WLD I++ +++++++ + I+
Sbjct: 165 VFTGIYIFEALIKILARGFILDEFSFLRDPWNWLDSIVIGIAIVSYIPGIT----IKLLP 220
Query: 1314 TMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
+RT R R L+A+S + ++V+V AL++++ + NV+++ IFA++G QLF G
Sbjct: 221 -LRTFRVFRALKAISVVSRLKVIVGALLRSVKKLVNVIILTFFCLSIFALVGQQLFMGSL 279
Query: 1374 -FKCVDMNHTTLSH-----------EIIPD---------KNACTLE---NYTWEN---SP 1406
KC+ + +S+ E P+ +AC+++ +T N +
Sbjct: 280 NLKCISRDCKNISNPEAYDHCFEKKENSPEFKMCGIWMGNSACSIQYECKHTKINPDYNY 339
Query: 1407 MNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXX 1466
NFD+ G ++L +F++ T W ++ +Q +R T +Y +
Sbjct: 340 TNFDNFGWSFLAMFRLMTQDSW----------EKLYQQTLRTTGLYSVFFFIVVIFLGSF 389
Query: 1467 XTLNLFIGVIIDNFNEQKKKAGGSLE 1492
+NL + V+ + EQ K +E
Sbjct: 390 YLINLTLAVVTMAYEEQNKNVAAEIE 415
Score = 81.0 bits (191), Expect = 3e-13
Identities = 70/285 (24%), Positives = 136/285 (47%), Gaps = 33/285 (11%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMI-----MPTTPTVES----TEVIFTGIYTFE 180
+R+ I+ H F FII IL++ +I + P ++ T++IFT I+ E
Sbjct: 1045 LRKTCYQIVKHSWFESFIIFVILLSSGALIFEDVHLENQPKIQELLNCTDIIFTHIFILE 1104
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVA 240
+K +A GF Y AW LDF+++ ++ T+ I+L L + RT R LR L+ ++
Sbjct: 1105 MVLKWVAFGF----GKYFTSAWCCLDFIIVIVSVTTL-INLMELKSFRTLRALRPLRALS 1159
Query: 241 IVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWG 300
G+K +V A+I ++ + +V+++ + VF ++G+ + G KC+ ++
Sbjct: 1160 QFEGMKVVVNALIGAIPAILNVLLVCLIFWLVFCILGVYFFSGKF-GKCINGTDSVINYT 1218
Query: 301 NLTDENWERFCQN-ETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDT 359
+T+++ C++ +W + ++ GN+ Y+ L + D
Sbjct: 1219 IITNKSQ---CESGNFSWINQKVNFDNVGNA---------YLALLQVATFKGW----MDI 1262
Query: 360 FGWAFLSAFRLMTQDYWEN-LYQLFFVVIIFLGSFYLVNLILAIV 403
A S + ++ N L ++FVV I GSF+ +NL + ++
Sbjct: 1263 IYAAVDSTEKEQQPEFESNSLGYIYFVVFIIFGSFFTLNLFIGVI 1307
Score = 74.5 bits (175), Expect = 3e-11
Identities = 43/145 (29%), Positives = 73/145 (50%), Gaps = 8/145 (5%)
Query: 691 EAGKVLKPSSDNPFIESSQQPNVVD----MRDVMVLNEIIEQAGRQSRASELNVSVYYFP 746
E+GK P SD+ + ++P +++ + + L+ E R L+
Sbjct: 473 ESGKDQPPGSDSDE-DCQKKPQLLEQTKRLSQNLSLDHFDEHGDPLQRQRALSAVSILTI 531
Query: 747 TAEDDEDGPTFKEKLLDCLMKGIDFFCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIV 806
T ++ E +E L C + VW+CC WL +K + ++ DPF EL IT+CI+
Sbjct: 532 TMKEQEKS---QEPCLPCGENLASKYLVWNCCPQWLCVKKVLRTVMTDPFTELAITICII 588
Query: 807 VNTLFMALDHHNMDKDMDKALKSGN 831
+NT+F+A++HH M+ +K L GN
Sbjct: 589 INTVFLAMEHHKMEASFEKMLNIGN 613
Score = 63.7 bits (148), Expect = 5e-08
Identities = 41/162 (25%), Positives = 79/162 (48%), Gaps = 14/162 (8%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTE-------VIFTGIYTFESA 182
+++V ++ P L I I++N + + M S E ++FT I+ E
Sbjct: 566 VKKVLRTVMTDPFTELAITICIIINTVFLAMEHHKMEASFEKMLNIGNLVFTSIFIAEMC 625
Query: 183 VKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMG---IDLGNLAALRTFRVLRALKTV 239
+K++A L P+ Y R WN D +V L++ + + + LR+FRVLR K
Sbjct: 626 LKIIA----LDPYHYFRRGWNIFDSIVALLSFADVMNCVLQKRSWPFLRSFRVLRVFKLA 681
Query: 240 AIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
P L T++ + SV L + ++ + + +F+++G+Q++
Sbjct: 682 KSWPTLNTLIKIIGNSVGALGSLTVVLVIVIFIFSVVGMQLF 723
Score = 60.9 bits (141), Expect = 3e-07
Identities = 40/160 (25%), Positives = 81/160 (50%), Gaps = 5/160 (3%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
++ + + E A+ I+++++ LA+E H + +L + +FT IF EM +K +A
Sbjct: 573 VMTDPFTELAITICIIINTVFLAME--HHKMEASFEKMLNIGNLVFTSIFIAEMCLKIIA 630
Query: 1274 LGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGM 1333
L YF W D I+ ++S + + + ++ R LR + ++ + +
Sbjct: 631 LDPYHYFRRGWNIFDSIVALLSFADVMNCVLQKRSWPFLRSFRVLRVFKLAKSWPTLNTL 690
Query: 1334 RVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
++ V A+ S+ V+LV +IF IF+++G+QLF +
Sbjct: 691 IKIIGNSVGALGSL-TVVLVIVIF--IFSVVGMQLFGRSF 727
Score = 54.0 bits (124), Expect = 4e-05
Identities = 40/168 (23%), Positives = 76/168 (45%), Gaps = 15/168 (8%)
Query: 1526 QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLL 1585
+++ + F M I+ + +N + M + S + + D +F I+ E L+
Sbjct: 119 RSLAIRVSVHSLFSMFIIGTVIINCVFMATGPAKNSNSNNT--DIAECVFTGIYIFEALI 176
Query: 1586 KIFAL-----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGR 1640
KI A + + +PWN D +V+ +I+S + I+ L +R +V R
Sbjct: 177 KILARGFILDEFSFLRDPWNWLDSIVIGIAIVSYIPGITIK--------LLPLRTFRVFR 228
Query: 1641 VLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
L+ + ++ ++ AL S+ L N+ +L F + IFA+ G FM
Sbjct: 229 ALKAISVVSRLKVIVGALLRSVKKLVNVIILTFFCLSIFALVGQQLFM 276
Score = 50.8 bits (116), Expect = 4e-04
Identities = 43/177 (24%), Positives = 85/177 (48%), Gaps = 23/177 (12%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT-------TPTVESTEVIFTGIYT 178
P N + + I+ +F + II+ I++N I M+ + ++ +F I+T
Sbjct: 1351 PLNKCQGLVFDIVTSQIFDIIIISLIILNMISMMAESYNQPKAMKSILDHLNWVFVVIFT 1410
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV-TMGIDLGN----------LAAL 227
E +K+ F L+ + Y + WN D VV+ L+ V TM L N +
Sbjct: 1411 LECLIKI----FALRQY-YFTNGWNLFDCVVVLLSIVSTMISTLENQEHIPFPPTLFRIV 1465
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
R R+ R L+ V G++T++ A++ S+ +L ++ +L + ++A++G+ + V
Sbjct: 1466 RLARIGRILRLVRAARGIRTLLFALMMSLPSLFNIGLLLFLIMFIYAILGMNWFSKV 1522
Score = 41.1 bits (92), Expect = 0.30
Identities = 34/145 (23%), Positives = 70/145 (48%), Gaps = 9/145 (6%)
Query: 792 VFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISI 851
+FD V L + +++TL +H + + ++ R+ +L ++ + L+
Sbjct: 1431 LFDCVVVLLSIVSTMISTLENQ-EHIPFPPTLFRIVRLARIGRILRLVRAARGIRTLLFA 1489
Query: 852 MGRTMGALGNLTFVLCIIIFIFAVMGMQLFGK-NYVDYVDRFPDGDLPRWNFTDFMHSFM 910
+ ++ +L N+ +L +I+FI+A++GM F K N +D D+ +NF F S +
Sbjct: 1490 LMMSLPSLFNIGLLLFLIMFIYAILGMNWFSKVNPESGID-----DI--FNFKTFASSML 1542
Query: 911 IVFRVLCGEWIESMWDCMLVGDVSC 935
+F++ +S+ ML SC
Sbjct: 1543 CLFQISTSAGWDSLLSPMLRSKESC 1567
>UniRef50_Q16JN2 Cluster: Voltage-gated sodium channel; n=3;
Endopterygota|Rep: Voltage-gated sodium channel - Aedes
aegypti (Yellowfever mosquito)
Length = 1115
Score = 735 bits (1817), Expect = 0.0
Identities = 362/743 (48%), Positives = 497/743 (66%), Gaps = 12/743 (1%)
Query: 1177 PADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALA 1236
P DC P++CY+K + Q W R + ++ FE V+ +I SS+ L
Sbjct: 368 PQDCFPQKCYEKCKCWDACLKTDAGQRWYRFRQNILQYVDTPAFEWFVLVLIFASSITLC 427
Query: 1237 LEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSL 1296
ED+HL L+ ILY+ + +F +IF IEML+KW+ALGF KYF++ W LDFIIV VS+
Sbjct: 428 FEDIHLDKNKQLKRILYWTNFVFCLIFVIEMLLKWIALGFTKYFSSFWTILDFIIVFVSV 487
Query: 1297 INFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLI 1356
+ + ++ +++RTLRALRPLRA+SR QGMR+VVNAL+ AIPSIFNVLLVCL+
Sbjct: 488 FSLLIE--ENENLKVLRSLRTLRALRPLRAISRWQGMRIVVNALMYAIPSIFNVLLVCLV 545
Query: 1357 FWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAY 1416
FWLIF+IMGVQ F GK+FKCVD + L I+ DK C +NYTW NS + FDHVG Y
Sbjct: 546 FWLIFSIMGVQFFGGKFFKCVDEDGELLPIHIVNDKWQCFAQNYTWINSKITFDHVGMGY 605
Query: 1417 LCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVI 1476
L LFQVATF+GW+++M DA+D+R V QP RE N+Y Y Y TLNLFIGVI
Sbjct: 606 LALFQVATFEGWMEVMADAVDARGVDLQPQREANLYAYFYFVIFIVCGSFFTLNLFIGVI 665
Query: 1477 IDNFNEQKKK-AGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTD 1535
IDNFN KKK GG LEMF+TE QK YY AMKK+G KKP K I RP + A+ +++
Sbjct: 666 IDNFNMLKKKYEGGVLEMFLTESQKHYYTAMKKLGRKKPQKVIKRPINQILAMFYDLSNS 725
Query: 1536 KKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYF 1595
++F++ I + I LNMLTM ++HY Q +L+ N F +F E ++KI LRYHYF
Sbjct: 726 RRFEIAIFVLIFLNMLTMGIEHYNQPHAVFFILEVSNAFFTTVFGLEAIVKIIGLRYHYF 785
Query: 1596 VEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLL 1655
PWN+FDF++V+ SI +++ DI+ +SPTLLRVVRV ++GR+LRL+K AKGIR LL
Sbjct: 786 TVPWNVFDFLLVLASIFGILMEDIMIDLPISPTLLRVVRVFRIGRILRLIKAAKGIRKLL 845
Query: 1656 FALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQM 1715
FAL +SLPALFNI LL L+ FI+AI GMS F HV+ +G LDD+ NF+TF +SM LLF++
Sbjct: 846 FALVVSLPALFNIGALLALITFIYAIIGMSLFGHVRQQGALDDMVNFETFGRSMQLLFRL 905
Query: 1716 STSAGWDGVLDGI-INEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIA 1774
TSAGW+ VL+ + I +C+L + +G+ G+CG + ITY S+++IS++IVINMYIA
Sbjct: 906 MTSAGWNDVLESLMIQPPDCELAQDTQGN-GDCGHPLLAITYFTSFIIISYMIVINMYIA 964
Query: 1775 VILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHK 1834
+ILEN++QA ++ + G+ +DD +M+Y W ++DP Q+I ++QLSDF+ L+PPL I K
Sbjct: 965 IILENFNQAHQEEEVGIVEDDLEMFYIRWSKYDPHAGQFIHFNQLSDFIASLDPPLGIPK 1024
Query: 1835 PNKYKIISMDIPICRGDMMFCVDILDALTKDFF-----ARKGNPIEETGDLEVGR--PEE 1887
PN ++S ++PI +G+ + C+DIL AL K +++ D + + P
Sbjct: 1025 PNTVALVSFNLPISKGNKIHCLDILHALVKHVLGHVEETENFKQLQDQMDQKFKKQFPTR 1084
Query: 1888 AGYEPVSSTLWRQREEYCARLIQ 1910
E VSST +R+E A+ IQ
Sbjct: 1085 KELEIVSSTRIWKRQEKAAKTIQ 1107
Score = 147 bits (357), Expect = 2e-33
Identities = 69/123 (56%), Positives = 88/123 (71%), Gaps = 6/123 (4%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+ LRV KLA+SW T+ +L+SI+ T+GALGNLTFVL I+I+IFAV+GMQLF K+Y
Sbjct: 168 LRGLRLLRVLKLAQSWTTMKVLLSIIISTIGALGNLTFVLVIVIYIFAVIGMQLFSKDYT 227
Query: 887 DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLV----GDVSCIPFFLAT 942
D+F +PRWNF DF HSFM++FR+LCGEWIE +WDCM G SC FL
Sbjct: 228 P--DKFAPDPVPRWNFNDFFHSFMMIFRILCGEWIEPLWDCMRAEEEEGASSCFAIFLPA 285
Query: 943 VVI 945
+V+
Sbjct: 286 LVM 288
Score = 117 bits (282), Expect = 3e-24
Identities = 78/260 (30%), Positives = 140/260 (53%), Gaps = 26/260 (10%)
Query: 1526 QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLL 1585
Q +++IV D F++ I L I LN L + L+H+ +E L+Y N +F +FS ECLL
Sbjct: 69 QNCLYKIVKDPLFELGITLCIVLNTLFLALEHHGMNENVRDALEYGNRVFTAVFSFECLL 128
Query: 1586 KIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLV 1645
K+ AL +F+ WN+FD ++V S+L L+ +++E L V+R ++ RVL+L
Sbjct: 129 KVMALSKDFFLCGWNIFDLIIVSASLLDLIF-ELMEG-------LTVLRGLRLLRVLKLA 180
Query: 1646 KGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM--HVKDKGGLDDV--YN 1701
+ ++ LL + ++ AL N+ +L +V++IFA+ GM F + DK D V +N
Sbjct: 181 QSWTTMKVLLSIIISTIGALGNLTFVLVIVIYIFAVIGMQLFSKDYTPDKFAPDPVPRWN 240
Query: 1702 FKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYL 1761
F F S +++F++ + + D C + E G+ +C L L
Sbjct: 241 FNDFFHSFMMIFRILCGEWIEPLWD-------CMRAEEEEGA-SSC------FAIFLPAL 286
Query: 1762 VISFLIVINMYIAVILENYS 1781
V+ +V+N+++A++L +++
Sbjct: 287 VMGNFMVLNLFLALLLNSFN 306
Score = 87.8 bits (208), Expect = 3e-15
Identities = 53/173 (30%), Positives = 95/173 (54%), Gaps = 8/173 (4%)
Query: 1201 WQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFT 1260
++ W + +K++++ FE + I+L++L LALE H ++D L Y +R+FT
Sbjct: 62 YEKWLQFQNCLYKIVKDPLFELGITLCIVLNTLFLALE--HHGMNENVRDALEYGNRVFT 119
Query: 1261 VIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRA 1320
+F E L+K +AL + +F W D IIV SL++ + L ++ +R LR
Sbjct: 120 AVFSFECLLKVMALS-KDFFLCGWNIFDLIIVSASLLDLIFEL-----MEGLTVLRGLRL 173
Query: 1321 LRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
LR L+ M+V+++ ++ I ++ N+ V +I IFA++G+QLF+ Y
Sbjct: 174 LRVLKLAQSWTTMKVLLSIIISTIGALGNLTFVLVIVIYIFAVIGMQLFSKDY 226
Score = 66.1 bits (154), Expect = 9e-09
Identities = 38/89 (42%), Positives = 54/89 (60%), Gaps = 3/89 (3%)
Query: 781 WLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAK 840
WL+FQ + +V DP EL ITLCIV+NTLF+AL+HH M++++ AL+ GN RVF
Sbjct: 65 WLQFQNCLYKIVKDPLFELGITLCIVLNTLFLALEHHGMNENVRDALEYGN--RVFTAVF 122
Query: 841 SWPTLNLLISIMGRTMGALGNLTFVLCII 869
S+ L L + + + G F L I+
Sbjct: 123 SFECL-LKVMALSKDFFLCGWNIFDLIIV 150
Score = 56.0 bits (129), Expect = 1e-05
Identities = 38/153 (24%), Positives = 77/153 (50%), Gaps = 13/153 (8%)
Query: 137 ILVHPLFSLFIITTILVNCILMIMP-------TTPTVESTEVIFTGIYTFESAVKVMARG 189
I+ PLF L I I++N + + + +E +FT +++FE +KVMA
Sbjct: 75 IVKDPLFELGITLCIVLNTLFLALEHHGMNENVRDALEYGNRVFTAVFSFECLLKVMA-- 132
Query: 190 FILQPFTYLRDAWNWLDFVVIALAYVTMGIDL-GNLAALRTFRVLRALKTVAIVPGLKTI 248
L +L WN D ++++ + + + +L L LR R+LR LK +K +
Sbjct: 133 --LSKDFFLC-GWNIFDLIIVSASLLDLIFELMEGLTVLRGLRLLRVLKLAQSWTTMKVL 189
Query: 249 VGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+ +I ++ L ++ + + + +FA++G+Q++
Sbjct: 190 LSIIISTIGALGNLTFVLVIVIYIFAVIGMQLF 222
Score = 45.6 bits (103), Expect = 0.014
Identities = 30/119 (25%), Positives = 58/119 (48%), Gaps = 8/119 (6%)
Query: 779 WLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKL 838
W+ L F KY F F + + IV ++F L N + + ++L++ LR +
Sbjct: 462 WIALGFTKY-----FSSFWTI-LDFIIVFVSVFSLLIEENENLKVLRSLRTLRALRPLRA 515
Query: 839 AKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDL 897
W + ++++ + + ++ N+ V + IF++MG+Q FG + VD DG+L
Sbjct: 516 ISRWQGMRIVVNALMYAIPSIFNVLLVCLVFWLIFSIMGVQFFGGKFFKCVDE--DGEL 572
Score = 40.3 bits (90), Expect = 0.52
Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 9/111 (8%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKN 884
+ + G LR+ K AK + L+ + ++ AL N+ +L +I FI+A++GM LFG
Sbjct: 824 RVFRIGRILRLIKAAKG---IRKLLFALVVSLPALFNIGALLALITFIYAIIGMSLFG-- 878
Query: 885 YVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVSC 935
+V D NF F S ++FR++ + + +++ C
Sbjct: 879 HVRQQGALDD----MVNFETFGRSMQLLFRLMTSAGWNDVLESLMIQPPDC 925
>UniRef50_Q7QIV0 Cluster: ENSANGP00000011132; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000011132 - Anopheles gambiae
str. PEST
Length = 2190
Score = 726 bits (1795), Expect = 0.0
Identities = 361/743 (48%), Positives = 494/743 (66%), Gaps = 12/743 (1%)
Query: 1177 PADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALA 1236
P DC P++CY+K + F Q W R + ++ FE V+ +I SS+ L
Sbjct: 1432 PQDCFPQKCYEKCKCWDTCLKTEFGQRWYRFRQFILQYVDTPAFEWFVLVLIFASSITLC 1491
Query: 1237 LEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSL 1296
ED+HL L+ ILY+ + +F +IF IEM +KW+ALGF KYF++ W LDF+IV VS+
Sbjct: 1492 FEDIHLDKNKELKRILYWTNLVFCMIFIIEMFLKWIALGFTKYFSSFWTILDFVIVFVSV 1551
Query: 1297 INFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLI 1356
+ + ++ +++RTLRALRPLRA+SR QGMR+VVNAL+ AIPSIFNVLLVCL+
Sbjct: 1552 FSLLIE--ENENLKVLRSLRTLRALRPLRAISRWQGMRIVVNALMYAIPSIFNVLLVCLV 1609
Query: 1357 FWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAY 1416
FWLIF+IMGVQ F GK+FKCVD + L I+ DK C NY+W NS + FDHVG Y
Sbjct: 1610 FWLIFSIMGVQFFGGKFFKCVDEDGELLPIHIVNDKWQCYALNYSWVNSKITFDHVGMGY 1669
Query: 1417 LCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVI 1476
L LFQVATF+GW+++M DA+D+R V QP RE N+Y YLY TLNLFIGVI
Sbjct: 1670 LALFQVATFEGWMEVMADAVDARGVDLQPQREANLYAYLYFVIFIVCGSFFTLNLFIGVI 1729
Query: 1477 IDNFNEQKKK-AGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTD 1535
IDNFN KKK GG LEMF+TE QK YY AMKK+G KKP K I RP + A+ +++
Sbjct: 1730 IDNFNMLKKKYEGGVLEMFLTESQKHYYTAMKKLGRKKPQKVIKRPINQFLAMFYDLSNS 1789
Query: 1536 KKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYF 1595
++F++ I + I LNMLTM ++HY Q VL+ N F +F E ++KI LRYHYF
Sbjct: 1790 RRFEIAIFVLIFLNMLTMGIEHYDQPHAVFFVLEVSNAFFTTVFGLEAIVKIVGLRYHYF 1849
Query: 1596 VEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLL 1655
PWN+FDF++V+ SI +++ DI+ +SPTLLRVVRV ++GR+LRL+K AKGIR LL
Sbjct: 1850 TVPWNVFDFLLVLASIFGILMEDIMIDLPISPTLLRVVRVFRIGRILRLIKAAKGIRKLL 1909
Query: 1656 FALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQM 1715
FAL +SLPALFNI LL L+ FI+AI GMS F HV+ +G LDD+ NF+TF +SM LLF++
Sbjct: 1910 FALVVSLPALFNIGALLALITFIYAIIGMSLFGHVRQQGALDDMVNFETFGRSMQLLFRL 1969
Query: 1716 STSAGWDGVLDGI-INEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIA 1774
TSAGW+ VL+ + I +C+L + G+CG + ITY S+++IS++IVINMYIA
Sbjct: 1970 MTSAGWNDVLESLMIQPPDCELA-LDFSINGDCGHPLLAITYFTSFIIISYMIVINMYIA 2028
Query: 1775 VILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHK 1834
+ILEN++QA ++ + G+ +DD +M+Y W ++DP Q+I ++QLSDF+ L+PPL I K
Sbjct: 2029 IILENFNQAHQEEEIGIVEDDLEMFYIRWSKYDPHAGQFIHFNQLSDFIASLDPPLGIPK 2088
Query: 1835 PNKYKIISMDIPICRGDMMFCVDILDALTKDFFAR-----KGNPIEETGDLEVGR--PEE 1887
PN ++S ++PI +G+ + C+DIL AL K +++ D + + P
Sbjct: 2089 PNTVALVSFNLPISKGNKIHCLDILHALVKHVLGHVEETDNFKQLQDQMDQKFKKQFPTR 2148
Query: 1888 AGYEPVSSTLWRQREEYCARLIQ 1910
E VSST +R+E A+ IQ
Sbjct: 2149 KELEIVSSTRIWKRQEKAAKTIQ 2171
Score = 328 bits (806), Expect = 9e-88
Identities = 161/321 (50%), Positives = 214/321 (66%), Gaps = 20/321 (6%)
Query: 102 TFVVISKG---KDIFRFSATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILM 158
TF V+SK I RF+ T +L+ P++P RR +Y+ + F F++ TIL NCI +
Sbjct: 1 TFCVVSKRFRKNYIHRFTGTKSLFCFTPWSPTRRACVYLATNQFFDYFVMATILFNCIFL 60
Query: 159 IMPTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMG 218
M + T+E E IF IYT E +K++A+GFIL +TYLR+ WNWLDFVVI Y T+
Sbjct: 61 AM--SETIEEAEYIFLAIYTSEMIIKMIAKGFILNKYTYLRNPWNWLDFVVITSGYATIA 118
Query: 219 IDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGL 278
+D+GNLA LRTFRVLRALKTV+I+PGLKTI+ A++ S K L +V+ LT+F L VFAL L
Sbjct: 119 LDVGNLAGLRTFRVLRALKTVSIMPGLKTIINALLHSFKQLAEVMTLTIFCLMVFALFAL 178
Query: 279 QIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYP-LCGNSSGAGQCE 337
Q+YMG L KCVK P D + N+T E+W + + NW + D P LCGN +GA C
Sbjct: 179 QVYMGELRNKCVKNLPSDLT--NVTHEDWYMWVNDTQNWIVDEDDMPMLCGNLTGARHCP 236
Query: 338 PGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQL-----------FFVV 386
P Y CL G NPN+GYT+FD F W+ L+ F+L+T DYWEN+Y + FF V
Sbjct: 237 PEYTCL-CIGENPNHGYTNFDNFMWSMLTTFQLITLDYWENVYNMVLATCGPMSVSFFTV 295
Query: 387 IIFLGSFYLVNLILAIVAMSY 407
++F GSFYL+NL+LA+VA+SY
Sbjct: 296 VVFFGSFYLINLMLAVVALSY 316
Score = 77.0 bits (181), Expect = 5e-12
Identities = 48/188 (25%), Positives = 88/188 (46%), Gaps = 17/188 (9%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W R L N +F+ V+ IL + + LA+ + +++ Y I+T
Sbjct: 29 WSPTRRACVYLATNQFFDYFVMATILFNCIFLAMSET-------IEEAEYIFLAIYTSEM 81
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRP 1323
I+M+ K L Y N W WLDF+++ + G+ RT R LR
Sbjct: 82 IIKMIAKGFILNKYTYLRNPWNWLDFVVITSGYATIALDVGNLAGL------RTFRVLRA 135
Query: 1324 LRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKCV---DM 1379
L+ +S M G++ ++NAL+ + + V+ + + ++FA+ +Q++ G+ KCV
Sbjct: 136 LKTVSIMPGLKTIINALLHSFKQLAEVMTLTIFCLMVFALFALQVYMGELRNKCVKNLPS 195
Query: 1380 NHTTLSHE 1387
+ T ++HE
Sbjct: 196 DLTNVTHE 203
Score = 77.0 bits (181), Expect = 5e-12
Identities = 44/130 (33%), Positives = 77/130 (59%), Gaps = 6/130 (4%)
Query: 1526 QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLL 1585
Q +++IV D F++ I L I LN + + L+H+ + LD N +F IF+ EC+L
Sbjct: 595 QNCLYKIVKDPLFELGITLCIVLNTMFLALEHHGMNANVRDALDIGNKVFTSIFTLECIL 654
Query: 1586 KIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLV 1645
K+ AL +F+ WN+FD ++V S+L L+ ++IE T+LR +R+ +VG +L
Sbjct: 655 KVMALSKDFFLCGWNIFDLIIVSVSLLDLIF-ELIE----GLTVLRGLRL-EVGEDSKLA 708
Query: 1646 KGAKGIRTLL 1655
+ + IR+++
Sbjct: 709 RSFERIRSIV 718
Score = 62.1 bits (144), Expect = 1e-07
Identities = 32/72 (44%), Positives = 46/72 (63%), Gaps = 5/72 (6%)
Query: 781 WLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAK 840
WL+FQ + +V DP EL ITLCIV+NT+F+AL+HH M+ ++ AL GN K+
Sbjct: 591 WLQFQNCLYKIVKDPLFELGITLCIVLNTMFLALEHHGMNANVRDALDIGN-----KVFT 645
Query: 841 SWPTLNLLISIM 852
S TL ++ +M
Sbjct: 646 SIFTLECILKVM 657
Score = 58.4 bits (135), Expect = 2e-06
Identities = 48/173 (27%), Positives = 83/173 (47%), Gaps = 26/173 (15%)
Query: 1523 WRP--QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFS 1580
W P +A V+ + T++ FD +M I N + + + SET ++ IF+ I++
Sbjct: 29 WSPTRRACVY-LATNQFFDYFVMATILFNCIFLAM-----SET----IEEAEYIFLAIYT 78
Query: 1581 SECLLKIFAL-----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRV 1635
SE ++K+ A +Y Y PWN DFVV+ ++ L D+ L +R
Sbjct: 79 SEMIIKMIAKGFILNKYTYLRNPWNWLDFVVITSGYATIAL-DVGN--------LAGLRT 129
Query: 1636 AKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
+V R L+ V G++T++ AL S L + L + +FA+F + +M
Sbjct: 130 FRVLRALKTVSIMPGLKTIINALLHSFKQLAEVMTLTIFCLMVFALFALQVYM 182
Score = 56.0 bits (129), Expect = 1e-05
Identities = 32/103 (31%), Positives = 59/103 (57%), Gaps = 3/103 (2%)
Query: 1201 WQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFT 1260
++GW + +K++++ FE + I+L+++ LALE H ++D L +++FT
Sbjct: 588 YEGWLQFQNCLYKIVKDPLFELGITLCIVLNTMFLALE--HHGMNANVRDALDIGNKVFT 645
Query: 1261 VIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAAL 1303
IF +E ++K +AL + +F W D IIV VSL++ + L
Sbjct: 646 SIFTLECILKVMALS-KDFFLCGWNIFDLIIVSVSLLDLIFEL 687
Score = 45.6 bits (103), Expect = 0.014
Identities = 30/119 (25%), Positives = 58/119 (48%), Gaps = 8/119 (6%)
Query: 779 WLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKL 838
W+ L F KY F F + + IV ++F L N + + ++L++ LR +
Sbjct: 1526 WIALGFTKY-----FSSFWTI-LDFVIVFVSVFSLLIEENENLKVLRSLRTLRALRPLRA 1579
Query: 839 AKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDL 897
W + ++++ + + ++ N+ V + IF++MG+Q FG + VD DG+L
Sbjct: 1580 ISRWQGMRIVVNALMYAIPSIFNVLLVCLVFWLIFSIMGVQFFGGKFFKCVDE--DGEL 1636
Score = 40.3 bits (90), Expect = 0.52
Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 9/111 (8%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKN 884
+ + G LR+ K AK + L+ + ++ AL N+ +L +I FI+A++GM LFG
Sbjct: 1888 RVFRIGRILRLIKAAKG---IRKLLFALVVSLPALFNIGALLALITFIYAIIGMSLFG-- 1942
Query: 885 YVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVSC 935
+V D NF F S ++FR++ + + +++ C
Sbjct: 1943 HVRQQGALDD----MVNFETFGRSMQLLFRLMTSAGWNDVLESLMIQPPDC 1989
>UniRef50_Q5D735 Cluster: Voltage-dependent sodium channel; n=1; Mya
arenaria|Rep: Voltage-dependent sodium channel - Mya
arenaria
Length = 1435
Score = 722 bits (1785), Expect = 0.0
Identities = 351/584 (60%), Positives = 446/584 (76%), Gaps = 6/584 (1%)
Query: 1196 DDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYM 1255
++S F + + R K F I++ YFET +I MIL SSLALALED++L RPIL+ +L YM
Sbjct: 854 ENSAFGEMFFGWRTKAFTFIQHKYFETLIIIMILASSLALALEDIYLDERPILKLVLIYM 913
Query: 1256 DRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTM 1315
D++FTV+FF+EMLIKW A G + YFT+AWCWLDF+IV +SLI VA + G ++ K M
Sbjct: 914 DQVFTVVFFLEMLIKWFAYGLKYYFTDAWCWLDFVIVAISLIMIVAKVANIGDAESLKAM 973
Query: 1316 RTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK 1375
RTLRALRPLRA+SR +GM+VVVNAL++AIPSIFNVLLVCL+FWLIF I+GVQ F GK+ K
Sbjct: 974 RTLRALRPLRAVSRWEGMKVVVNALIKAIPSIFNVLLVCLVFWLIFGIVGVQFFKGKFHK 1033
Query: 1376 CVDMNHTTLSHEIIPDKNACTLE--NYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMN 1433
CVD T +++ + +K C NY+WENS +NFD+V +YL LFQVAT+KGWI I+
Sbjct: 1034 CVDFEGTRVNYSEVKNKTECLNHPNNYSWENSQINFDNVLNSYLALFQVATYKGWIDIIR 1093
Query: 1434 DAIDSR-EVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLE 1492
D++DS E+ QP E N MY+Y TLNLFIGVIIDNFN+QKKKAG SLE
Sbjct: 1094 DSVDSPPEIDDQPNDEINPLMYIYFVFFIVFGSFFTLNLFIGVIIDNFNKQKKKAG-SLE 1152
Query: 1493 MFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLT 1552
MFMTEDQKKYYNAMK+M SK P K+IPRP W P I+F++ T +KFD++IM I LNM+T
Sbjct: 1153 MFMTEDQKKYYNAMKRMQSKSPQKSIPRPTWFPGNILFDVTTTQKFDIVIMAVIILNMVT 1212
Query: 1553 MTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSIL 1612
MT++ Y+Q + F+ L ++N FIVIF++EC++KI LR +YF PWN+FDFVVV+ SIL
Sbjct: 1213 MTMEXYEQXQAFTRGLYWVNFSFIVIFTAECIMKITGLRLYYFKIPWNVFDFVVVVLSIL 1272
Query: 1613 SLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLL 1672
+ L +E+ VSPTLLRVVRV +VGRVLRLVK AKGIRTLLF+LA+SLPALFNI LLL
Sbjct: 1273 GVSLGGYLEELPVSPTLLRVVRVFRVGRVLRLVKSAKGIRTLLFSLAVSLPALFNIGLLL 1332
Query: 1673 FLVMFIFAIFGMSFFMHVKDK-GGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINE 1731
FLVMFI+A+FGM+FF VK GGLDDV+NF+TF +S+I LFQM TSAGWDGVL G++N
Sbjct: 1333 FLVMFIWAVFGMNFFKDVKTPYGGLDDVFNFQTFFKSIITLFQMCTSAGWDGVLKGLMNT 1392
Query: 1732 EECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAV 1775
++C+ + + CGS + + YL++YLVISFL+V+NMYIAV
Sbjct: 1393 KDCN-SNPQEDEKNTCGSYPLAVMYLVTYLVISFLVVVNMYIAV 1435
Score = 182 bits (443), Expect = 9e-44
Identities = 100/213 (46%), Positives = 128/213 (60%), Gaps = 13/213 (6%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L++ LRVFKLAKSW TLN+LISI+ RT+GALGNL FVL I+IFIFA+MG QLF + Y
Sbjct: 541 LRTFRLLRVFKLAKSWQTLNMLISIVARTLGALGNLXFVLGIVIFIFAIMGQQLFAQYYP 600
Query: 887 DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVSCIPFFLATVVIX 946
Y F D D+PRWNF DF+HSFMIVFRVLCGEWI+SMW C+ CIPFFL T +I
Sbjct: 601 PY---FGD-DIPRWNFKDFLHSFMIVFRVLCGEWIDSMWYCIEAAGYPCIPFFLLTYIIG 656
Query: 947 XXXXXXXXXXXXXXXXXXXXXXTPTADQDT----NKIAEAFNRISRFIDWIKRNVADFLK 1002
+ + +++ NK+ EA +R SR +WIK +V +K
Sbjct: 657 NLVVLNLFLALLIASFGTESLASDSGEEEAPAAPNKLQEAISRFSRLGNWIKVHVIVVVK 716
Query: 1003 LLKNKLTNQIAIHAPERVDNELELGTDLDDAVL 1035
+ K P VD+ + GT LD +V+
Sbjct: 717 RTREKKR-----PLPVTVDSGGKNGTLLDGSVI 744
Score = 156 bits (378), Expect = 7e-36
Identities = 81/146 (55%), Positives = 95/146 (65%), Gaps = 17/146 (11%)
Query: 273 FALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSG 332
FAL+G+Q+Y G L KC+ E+ N+TDE W F N +N +CGN+S
Sbjct: 1 FALIGMQLYSGRLRNKCILNVGENLG-PNVTDEVWTNFTLNTSNHIET-----MCGNAST 54
Query: 333 AGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQL---------- 382
AGQC GY CLQ G NPN+GYTSFD FGWA L +FRLMTQDYWENLY L
Sbjct: 55 AGQCPEGYECLQYIGENPNFGYTSFDNFGWALLCSFRLMTQDYWENLYMLVLRAEGLPHS 114
Query: 383 -FFVVIIFLGSFYLVNLILAIVAMSY 407
+F+ +I LGSFYLVNLILAIVAMSY
Sbjct: 115 FYFIFVILLGSFYLVNLILAIVAMSY 140
Score = 100 bits (240), Expect = 3e-19
Identities = 68/200 (34%), Positives = 104/200 (52%), Gaps = 13/200 (6%)
Query: 1521 PRW--RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVI 1578
P W + QAIV + D D+ I L I N + D + ++ L N +F I
Sbjct: 434 PVWFAKIQAIVGFFILDAFVDLFITLCILANTAFLGADQHGLTQEAMHTLGAGNQVFTYI 493
Query: 1579 FSSECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAK 1637
F+ EC LKI AL + Y + WN+FDF+VV FS L +L D+ L V+R +
Sbjct: 494 FAIECFLKIIALGFIQYMKDGWNVFDFIVVAFSFLEKLLEDVKG--------LSVLRTFR 545
Query: 1638 VGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLD 1697
+ RV +L K + + L+ +A +L AL N+ +L +V+FIFAI G F D
Sbjct: 546 LLRVFKLAKSWQTLNMLISIVARTLGALGNLXFVLGIVIFIFAIMGQQLFAQYYPPYFGD 605
Query: 1698 DV--YNFKTFVQSMILLFQM 1715
D+ +NFK F+ S +++F++
Sbjct: 606 DIPRWNFKDFLHSFMIVFRV 625
Score = 95.5 bits (227), Expect = 1e-17
Identities = 81/324 (25%), Positives = 146/324 (45%), Gaps = 47/324 (14%)
Query: 1523 WRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLD--HYQQSETFSAVLDYLNMIFIVIFS 1580
WR +A F + K F+ +I++ I + L + L+ + + VL Y++ +F V+F
Sbjct: 865 WRTKAFTF--IQHKYFETLIIIMILASSLALALEDIYLDERPILKLVLIYMDQVFTVVFF 922
Query: 1581 SECLLKIFA--LRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKV 1638
E L+K FA L+Y YF + W DFV+V S++ +V L+ +R +
Sbjct: 923 LEMLIKWFAYGLKY-YFTDAWCWLDFVIVAISLIMIVAK---VANIGDAESLKAMRTLRA 978
Query: 1639 GRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSF------------ 1686
R LR V +G++ ++ AL ++P++FN+ L+ + IF I G+ F
Sbjct: 979 LRPLRAVSRWEGMKVVVNALIKAIPSIFNVLLVCLVFWLIFGIVGVQFFKGKFHKCVDFE 1038
Query: 1687 -----FMHVKDKGGL----------DDVYNFKTFVQSMILLFQMSTSAGW-DGVLDGIIN 1730
+ VK+K + NF + S + LFQ++T GW D + D + +
Sbjct: 1039 GTRVNYSEVKNKTECLNHPNNYSWENSQINFDNVLNSYLALFQVATYKGWIDIIRDSVDS 1098
Query: 1731 EEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDV--Q 1788
E D N+ +P + Y + ++V +N++I VI++N+++ +
Sbjct: 1099 PPEIDDQPNDEINP-------LMYIYFVFFIVFGSFFTLNLFIGVIIDNFNKQKKKAGSL 1151
Query: 1789 EGLTDDDYDMYYEIWQRFDPDGSQ 1812
E +D YY +R Q
Sbjct: 1152 EMFMTEDQKKYYNAMKRMQSKSPQ 1175
Score = 83.0 bits (196), Expect = 7e-14
Identities = 90/312 (28%), Positives = 139/312 (44%), Gaps = 43/312 (13%)
Query: 531 ASLSLPGSPFNLRRGSRGSHQMALXXXXXXXXXXXXXXXXLVLSTYLDAQEHLPYADDSN 590
AS SLPGSP+ RR S S L LV +L++ +LPYADDSN
Sbjct: 224 ASFSLPGSPYFRRRRSNPSR---LSIKLAKQLRHQAERQPLV---HLESL-NLPYADDSN 276
Query: 591 AVTPMSEENGAIIIPVYYANLGSRHSSYTSHQSRLSYTSHGDLLGGGKAQTKEARLRGRS 650
AVTP S++ +P ++ L + S + L +S ++ R+
Sbjct: 277 AVTPCSDDIRLCTLPSKFSILARK----ASMRRALEESSR---------RSSNVSQSSRT 323
Query: 651 ASRNHSVTSQPHAYPLPRQDSSLAS--RPLREYEVSTTECTDEAGKVL-KPSSDNPFIES 707
+ HS PH+ P + + R ++ ++ + E TD+ G L K S S
Sbjct: 324 SHSRHS----PHS-PTDKLSFLMEQFERRSKQNQLISAEKTDDPGYDLHKRSKGYCRTPS 378
Query: 708 SQQPNVVDMRDVMVLNEIIEQAGRQSRASELNVSVYYFPTAEDDEDGPTFKEKLLDCLMK 767
+ Q VD +DVMVL E+I+ SR + +S F E++ K+K+ L
Sbjct: 379 ASQ---VDPKDVMVLRELIDHVETNSRTRSV-LSGSIFSMMENEP----LKDKIWRLL-- 428
Query: 768 GIDFFCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKAL 827
C W+ + + Q V + D FV+LFITLCI+ NT F+ D H + ++ L
Sbjct: 429 -----CSWEVPVWFAKIQAIVGFFILDAFVDLFITLCILANTAFLGADQHGLTQEAMHTL 483
Query: 828 KSGNYLRVFKLA 839
+GN + + A
Sbjct: 484 GAGNQVFTYIFA 495
Score = 77.4 bits (182), Expect = 4e-12
Identities = 50/199 (25%), Positives = 98/199 (49%), Gaps = 15/199 (7%)
Query: 131 RRVAIYILVHPLFSLFIITTILVNCILMIMPTT-----PTVESTEVIFTGIYTFESAVKV 185
R A + H F II IL + + + + P ++ + ++T +++
Sbjct: 866 RTKAFTFIQHKYFETLIIIMILASSLALALEDIYLDERPILKLVLIYMDQVFTVVFFLEM 925
Query: 186 MARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN------LAALRTFRVLRALKTV 239
+ + F Y DAW WLDFV++A++ + + + N L A+RT R LR L+ V
Sbjct: 926 LIKWFAYGLKYYFTDAWCWLDFVIVAISLIMIVAKVANIGDAESLKAMRTLRALRPLRAV 985
Query: 240 AIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSW 299
+ G+K +V A+I+++ ++ +V+++ + +F ++G+Q + G KCV +G+
Sbjct: 986 SRWEGMKVVVNALIKAIPSIFNVLLVCLVFWLIFGIVGVQFFKGKF-HKCVDF---EGTR 1041
Query: 300 GNLTDENWERFCQNETNWY 318
N ++ + C N N Y
Sbjct: 1042 VNYSEVKNKTECLNHPNNY 1060
Score = 70.9 bits (166), Expect = 3e-10
Identities = 46/157 (29%), Positives = 80/157 (50%), Gaps = 12/157 (7%)
Query: 1220 FETAVITMILLSSLALALEDVHLPHRPILQDILYYM---DRIFTVIFFIEMLIKWLALGF 1276
F IT+ +L++ A D H + Q+ ++ + +++FT IF IE +K +ALGF
Sbjct: 452 FVDLFITLCILANTAFLGADQH----GLTQEAMHTLGAGNQVFTYIFAIECFLKIIALGF 507
Query: 1277 QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVV 1336
+Y + W DFI+V S + + ++ +RT R LR + Q + ++
Sbjct: 508 IQYMKDGWNVFDFIVVAFSFLEKLLE-----DVKGLSVLRTFRLLRVFKLAKSWQTLNML 562
Query: 1337 VNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
++ + + + ++ N+ V I IFAIMG QLFA Y
Sbjct: 563 ISIVARTLGALGNLXFVLGIVIFIFAIMGQQLFAQYY 599
Score = 70.1 bits (164), Expect = 6e-10
Identities = 44/163 (26%), Positives = 80/163 (49%), Gaps = 12/163 (7%)
Query: 127 FNPIRRVAIYILVHPLFSLFIITTILVNCILM-------IMPTTPTVESTEVIFTGIYTF 179
F I+ + + ++ LFI IL N + T+ + +FT I+
Sbjct: 437 FAKIQAIVGFFILDAFVDLFITLCILANTAFLGADQHGLTQEAMHTLGAGNQVFTYIFAI 496
Query: 180 ESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGNLAALRTFRVLRALKT 238
E +K++A GFI Y++D WN DF+V+A +++ + D+ L+ LRTFR+LR K
Sbjct: 497 ECFLKIIALGFI----QYMKDGWNVFDFIVVAFSFLEKLLEDVKGLSVLRTFRLLRVFKL 552
Query: 239 VAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
L ++ V ++ L ++ + + +FA+MG Q++
Sbjct: 553 AKSWQTLNMLISIVARTLGALGNLXFVLGIVIFIFAIMGQQLF 595
Score = 49.2 bits (112), Expect = 0.001
Identities = 39/160 (24%), Positives = 72/160 (45%), Gaps = 21/160 (13%)
Query: 143 FSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFT-----Y 197
F + I+ I++N + M M E + G+Y + V+ + T Y
Sbjct: 1198 FDIVIMAVIILNMVTMTMEX---YEQXQAFTRGLYWVNFSFIVIFTAECIMKITGLRLYY 1254
Query: 198 LRDAWNWLDFVVIALAYVTMGIDLGN-----------LAALRTFRVLRALKTVAIVPGLK 246
+ WN DFVV+ L+ +G+ LG L +R FRV R L+ V G++
Sbjct: 1255 FKIPWNVFDFVVVVLS--ILGVSLGGYLEELPVSPTLLRVVRVFRVGRVLRLVKSAKGIR 1312
Query: 247 TIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLT 286
T++ ++ S+ L ++ +L + ++A+ G+ + V T
Sbjct: 1313 TLLFSLAVSLPALFNIGLLLFLVMFIWAVFGMNFFKDVKT 1352
Score = 37.9 bits (84), Expect = 2.8
Identities = 31/99 (31%), Positives = 52/99 (52%), Gaps = 11/99 (11%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
RV +L KS + L+ + ++ AL N+ +L +++FI+AV GM F K+ + P
Sbjct: 1300 RVLRLVKSAKGIRTLLFSLAVSLPALFNIGLLLFLVMFIWAVFGMNFF-KDV-----KTP 1353
Query: 894 DGDLPR-WNFTDFMHSFMIVFRVLCGEWIESMWDCMLVG 931
G L +NF F S + +F+ +C + WD +L G
Sbjct: 1354 YGGLDDVFNFQTFFKSIITLFQ-MC---TSAGWDGVLKG 1388
>UniRef50_Q9W0Y8 Cluster: Sodium channel protein 60E; n=3; Drosophila
melanogaster|Rep: Sodium channel protein 60E - Drosophila
melanogaster (Fruit fly)
Length = 2327
Score = 720 bits (1781), Expect = 0.0
Identities = 360/747 (48%), Positives = 495/747 (66%), Gaps = 16/747 (2%)
Query: 1177 PADCCPEQCYQKF----PFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSS 1232
P DC P++CY F P+ D+ + W +R +++ FE V+ +I SS
Sbjct: 1564 PDDCFPQKCYDHFYFRCPWFMSCMDTQSAKHWTRVRTAVLTVVDTPAFEWFVLVLIFASS 1623
Query: 1233 LALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIV 1292
+ L ED++L L+ +LY+++ F +IF +EM++KWLALGF KYFT+ W LDFIIV
Sbjct: 1624 ITLCFEDINLDKNKTLKRVLYWINFSFCLIFVVEMILKWLALGFSKYFTSFWTILDFIIV 1683
Query: 1293 MVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLL 1352
VS+ + + ++ +++RTLRALRPLRA+SR QGMR+VVNAL+ AIPSIFNVLL
Sbjct: 1684 FVSVFSLLIE--ENENLKVLRSLRTLRALRPLRAISRWQGMRIVVNALMYAIPSIFNVLL 1741
Query: 1353 VCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHV 1412
VCL+FWLIF+IMGVQ F GK+FKCV+ L + DK C +NYTW NS + FDHV
Sbjct: 1742 VCLVFWLIFSIMGVQFFGGKFFKCVNEMGELLPITEVNDKWDCIEQNYTWINSKITFDHV 1801
Query: 1413 GKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLF 1472
G YL L QVATF+GW+++M DA+D+R V QP RE N+Y Y+Y TLNLF
Sbjct: 1802 GMGYLALLQVATFEGWMEVMADAVDARGVDLQPQREANLYAYIYFVIFIVCGSFFTLNLF 1861
Query: 1473 IGVIIDNFNEQKKK-AGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFE 1531
IGVIIDNFN KKK GG LEMF+TE QK YY AMKK+G KKP K I RP A+ ++
Sbjct: 1862 IGVIIDNFNMLKKKYEGGVLEMFLTESQKHYYTAMKKLGRKKPQKVIKRPINHFLAMFYD 1921
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR 1591
+ ++F++ I + I LNMLTM ++HY Q +L+ N F +F E ++KI LR
Sbjct: 1922 LSNSRRFEIAIFVLIFLNMLTMGIEHYDQPHAVFFILEVSNAFFTTVFGLEAIVKIVGLR 1981
Query: 1592 YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGI 1651
YHYF PWN+FDF++V+ SI +++ DI+ +SPTLLRVVRV ++GR+LRL+K AKGI
Sbjct: 1982 YHYFTVPWNVFDFLLVLASIFGILMEDIMIDLPISPTLLRVVRVFRIGRILRLIKAAKGI 2041
Query: 1652 RTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMIL 1711
R LLFAL +SLPALFNI LL L+ FI+AI GMS F +VK +G LDD+ NF+TF +SM L
Sbjct: 2042 RKLLFALVVSLPALFNIGALLGLITFIYAILGMSLFGNVKLQGALDDMVNFQTFGRSMQL 2101
Query: 1712 LFQMSTSAGWDGVLDGI-INEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVIN 1770
LF++ TSAGW+ VL+ + I +CD P + GNCG + ITY S+++IS++IVIN
Sbjct: 2102 LFRLMTSAGWNDVLESLMIQPPDCD-PFIHGHTNGNCGHPLLAITYFTSFIIISYMIVIN 2160
Query: 1771 MYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPL 1830
MYIA+ILEN++QA ++ + G+ +DD +M+Y W ++DP +Q+I + QLSDF+ L+PPL
Sbjct: 2161 MYIAIILENFNQAHQEEEIGIVEDDLEMFYIRWSKYDPHATQFIHFSQLSDFIASLDPPL 2220
Query: 1831 QIHKPNKYKIISMDIPICRGDMMFCVDILDALTKDFFAR-----KGNPIEETGDLEVGR- 1884
I KPN ++S ++PI +G+ + C+DIL AL K ++E D++ +
Sbjct: 2221 GISKPNNVALVSFNLPISKGNKIHCLDILHALVKHVLGHVEETDNFKQLQEQMDVKFKKQ 2280
Query: 1885 -PEEAGYEPVSSTLWRQREEYCARLIQ 1910
P E VSST +R+E A+ IQ
Sbjct: 2281 FPTRKELEIVSSTRIWKRQEKAAKTIQ 2307
Score = 344 bits (846), Expect = 1e-92
Identities = 172/362 (47%), Positives = 239/362 (66%), Gaps = 22/362 (6%)
Query: 61 PQPDATLEQGLPLPVRMQGSFPLELASTPLEDIDPFYHNQTTFVVISKG---KDIFRFSA 117
P+ A++E G LP + + FP + PLE+ID F + +T F V+SK I RF+
Sbjct: 45 PRTKASVEDGDVLPRKFE-PFPEHMYGKPLEEIDTFIYEET-FCVVSKRFRKNYIHRFTG 102
Query: 118 TNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVIFTGIY 177
T +L++ P++P RRV +YI + F ++ TIL NCI + M T TVE E IF IY
Sbjct: 103 TKSLFLFYPWSPARRVCVYIATNQFFDYCVMATILFNCIFLAM--TETVEEAEYIFLAIY 160
Query: 178 TFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALK 237
+ E +K++A+GF+L +TYLR+ WNWLDFVVI Y T+G+++GNLA LRTFRVLRALK
Sbjct: 161 SIEMVIKIIAKGFLLNKYTYLRNPWNWLDFVVITSGYATIGMEVGNLAGLRTFRVLRALK 220
Query: 238 TVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDG 297
TV+I+PGLKTI+ A++ S + L +V+ LT+F L VFAL LQ+YMG L KCV+ P D
Sbjct: 221 TVSIMPGLKTIINALLHSFRQLAEVMTLTIFCLMVFALFALQVYMGELRNKCVRQVPTD- 279
Query: 298 SWGNLTDENWERFCQNETNWYGEGGDYP-LCGNSSGAGQCEPGYVCLQGFGPNPNYGYTS 356
W N++ +W+ + + NW + + P LCGN +GA C YVCL G NPN+GYT+
Sbjct: 280 -WTNVSHTDWQIWVNDTDNWLYDEDELPVLCGNLTGARHCPFEYVCL-CVGENPNHGYTN 337
Query: 357 FDTFGWAFLSAFRLMTQDYWENLYQL-----------FFVVIIFLGSFYLVNLILAIVAM 405
FD F W+ L+ F+L+T DYWEN+Y + FF V++F GSFYL+NL+LA+VA+
Sbjct: 338 FDNFMWSMLTTFQLITLDYWENVYNMVLATCGPMSVSFFTVVVFFGSFYLINLMLAVVAL 397
Query: 406 SY 407
SY
Sbjct: 398 SY 399
Score = 77.4 bits (182), Expect = 4e-12
Identities = 43/130 (33%), Positives = 76/130 (58%), Gaps = 6/130 (4%)
Query: 1526 QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLL 1585
Q ++++V D F++ I L I LN + ++H+ SE+F LD N +F IF+ EC++
Sbjct: 678 QNCLYKVVRDPLFELAITLCIVLNTAFLAMEHHGMSESFRNALDVGNKVFTSIFTFECIV 737
Query: 1586 KIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLV 1645
K+ AL +F+ WN+FD ++V S+L DII + ++LR +R+ +VG +L
Sbjct: 738 KLMALSKDFFLCGWNIFDLLIVTASLL-----DIIFELVDGLSVLRGLRL-EVGEESKLA 791
Query: 1646 KGAKGIRTLL 1655
+ + +R L+
Sbjct: 792 RSIERVRDLI 801
Score = 74.9 bits (176), Expect = 2e-11
Identities = 49/179 (27%), Positives = 87/179 (48%), Gaps = 22/179 (12%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W R + N +F+ V+ IL + + LA+ + +++ Y IF I+
Sbjct: 112 WSPARRVCVYIATNQFFDYCVMATILFNCIFLAMTET-------VEEAEY----IFLAIY 160
Query: 1264 FIEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLR 1319
IEM+IK +A GF Y N W WLDF+++ + G+ RT R
Sbjct: 161 SIEMVIKIIAKGFLLNKYTYLRNPWNWLDFVVITSGYATIGMEVGNLAGL------RTFR 214
Query: 1320 ALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKCV 1377
LR L+ +S M G++ ++NAL+ + + V+ + + ++FA+ +Q++ G+ KCV
Sbjct: 215 VLRALKTVSIMPGLKTIINALLHSFRQLAEVMTLTIFCLMVFALFALQVYMGELRNKCV 273
Score = 59.7 bits (138), Expect = 8e-07
Identities = 26/51 (50%), Positives = 34/51 (66%)
Query: 781 WLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGN 831
WL+FQ + +V DP EL ITLCIV+NT F+A++HH M + AL GN
Sbjct: 674 WLQFQNCLYKVVRDPLFELAITLCIVLNTAFLAMEHHGMSESFRNALDVGN 724
Score = 53.6 bits (123), Expect = 5e-05
Identities = 45/172 (26%), Positives = 78/172 (45%), Gaps = 24/172 (13%)
Query: 1523 WRP-QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSS 1581
W P + + I T++ FD +M I N + + + +ET ++ IF+ I+S
Sbjct: 112 WSPARRVCVYIATNQFFDYCVMATILFNCIFLAM-----TET----VEEAEYIFLAIYSI 162
Query: 1582 ECLLKIFAL-----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVA 1636
E ++KI A +Y Y PWN DFVV+ ++ + L +R
Sbjct: 163 EMVIKIIAKGFLLNKYTYLRNPWNWLDFVVITSGYATIGM---------EVGNLAGLRTF 213
Query: 1637 KVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
+V R L+ V G++T++ AL S L + L + +FA+F + +M
Sbjct: 214 RVLRALKTVSIMPGLKTIINALLHSFRQLAEVMTLTIFCLMVFALFALQVYM 265
Score = 48.0 bits (109), Expect = 0.003
Identities = 30/116 (25%), Positives = 59/116 (50%), Gaps = 5/116 (4%)
Query: 1201 WQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFT 1260
++ W + +K++ + FE A+ I+L++ LA+E H ++ L +++FT
Sbjct: 671 YESWLQFQNCLYKVVRDPLFELAITLCIVLNTAFLAME--HHGMSESFRNALDVGNKVFT 728
Query: 1261 VIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMR 1316
IF E ++K +AL + +F W D +IV SL++ + L G+ + +R
Sbjct: 729 SIFTFECIVKLMALS-KDFFLCGWNIFDLLIVTASLLDIIFEL--VDGLSVLRGLR 781
Score = 43.2 bits (97), Expect = 0.074
Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 9/114 (7%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKN 884
+ + G LR+ K AK + L+ + ++ AL N+ +L +I FI+A++GM LFG
Sbjct: 2024 RVFRIGRILRLIKAAKG---IRKLLFALVVSLPALFNIGALLGLITFIYAILGMSLFGN- 2079
Query: 885 YVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVSCIPF 938
V D NF F S ++FR++ + + +++ C PF
Sbjct: 2080 -VKLQGALDD----MVNFQTFGRSMQLLFRLMTSAGWNDVLESLMIQPPDCDPF 2128
Score = 42.3 bits (95), Expect = 0.13
Identities = 27/112 (24%), Positives = 54/112 (48%), Gaps = 6/112 (5%)
Query: 779 WLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKL 838
WL L F KY F F + + IV ++F L N + + ++L++ LR +
Sbjct: 1662 WLALGFSKY-----FTSFWTI-LDFIIVFVSVFSLLIEENENLKVLRSLRTLRALRPLRA 1715
Query: 839 AKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVD 890
W + ++++ + + ++ N+ V + IF++MG+Q FG + V+
Sbjct: 1716 ISRWQGMRIVVNALMYAIPSIFNVLLVCLVFWLIFSIMGVQFFGGKFFKCVN 1767
>UniRef50_O02037 Cluster: Voltage-gated sodium channel homolog BdNa1;
n=1; Bdelloura candida|Rep: Voltage-gated sodium channel
homolog BdNa1 - Bdelloura candida (Horseshoe crab
flatworm)
Length = 1699
Score = 720 bits (1779), Expect = 0.0
Identities = 334/674 (49%), Positives = 478/674 (70%), Gaps = 11/674 (1%)
Query: 1200 FWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIF 1259
+++ W +R TFK++++ YFET ++ MI SSL + LED +LP+ P+L++ +Y +D++F
Sbjct: 968 YYRVWWRIRCLTFKVVDHKYFETFILFMIAFSSLTMTLEDKYLPNYPMLENTIYILDKVF 1027
Query: 1260 TVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLR 1319
T++F +EML+KW+A+G KYF + W LDF IVM++LI+ + A K MRTLR
Sbjct: 1028 TIVFLMEMLLKWMAIGLYKYFKDPWSCLDFAIVMIALISLMPF--DMSRYDALKAMRTLR 1085
Query: 1320 ALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDM 1379
ALRPLRA+SR +GMR+VVNAL+QAIPSIFNV++VCL+FWLIF+I+GVQ F G+++KC+
Sbjct: 1086 ALRPLRAISRWEGMRIVVNALIQAIPSIFNVMVVCLVFWLIFSIIGVQRFGGRFYKCIYK 1145
Query: 1380 NHTT-LSHEIIPDKNACTLE----NYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMND 1434
+ + +S I+ K AC N TW NS ++FD V L LFQVATFKGW I+ D
Sbjct: 1146 DSKSQVSPLIVNSKIACETFANQLNITWINSKIHFDDVVNGLLALFQVATFKGWTDIIKD 1205
Query: 1435 AIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMF 1494
++D ++ +QP + Y+Y TLNLFIGVIIDNFN QKKK GGSLEMF
Sbjct: 1206 SVDVTDIDKQPRHNNSRINYIYYVLFIIFGSFFTLNLFIGVIIDNFNVQKKKVGGSLEMF 1265
Query: 1495 MTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMT 1554
MT+DQKKYYNA++KM S P K IP+P+ + + I +K FD++IM FI LN LTM
Sbjct: 1266 MTDDQKKYYNAIQKMSSSSPQKPIPKPKNHISIVFYNICKNKNFDIVIMGFIVLNTLTMC 1325
Query: 1555 LDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSL 1614
++ Q + + VLD + +F++IF+ E ++K+ R+ YF +PWN+FDF VV+FS ++
Sbjct: 1326 IEFQDQPKLLTRVLDIVGRVFLLIFAGEFIMKLIGFRWFYFKDPWNVFDFSVVVFSTIAW 1385
Query: 1615 VLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFL 1674
+L + + PTL+R+VR+ ++ RVLRLVK A+GIRTLLF+L +SLPALFNI LLL L
Sbjct: 1386 ILQFFESIFPLDPTLIRIVRLFRITRVLRLVKSARGIRTLLFSLVVSLPALFNIALLLML 1445
Query: 1675 VMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEEC 1734
VMFI+AI G+SFF +V K G+D+ +NF+TF SMI+LFQ+ST+ GW V+DG++N E
Sbjct: 1446 VMFIYAIMGLSFFANVPHKYGIDETFNFETFFNSMIILFQISTTGGWHSVMDGLMNNESP 1505
Query: 1735 DLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDD 1794
+ + P CGS + +YL+SYL+I+ +++NMYIAVILEN+SQAT+D Q GLT D
Sbjct: 1506 ECSE----IPSPCGSKLLASSYLISYLIINAFVIVNMYIAVILENFSQATKDFQMGLTQD 1561
Query: 1795 DYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHKPNKYKIISMDIPICRGDMMF 1854
DYD++YE+W+++DP+ + +I L DF+D + PL I KPNK ++ ++IPIC+G+ +
Sbjct: 1562 DYDLFYEVWEKYDPEATGFIPLSDLYDFVDQIGQPLGIAKPNKIQLAILEIPICQGNNIC 1621
Query: 1855 CVDILDALTKDFFA 1868
C+D+LD LTK++ A
Sbjct: 1622 CMDVLDILTKNYLA 1635
Score = 341 bits (837), Expect = 2e-91
Identities = 179/365 (49%), Positives = 241/365 (66%), Gaps = 30/365 (8%)
Query: 63 PDATLEQGLPLPVRMQGSFPLE-LASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNAL 121
PD LE+G L + F + +++IDP+Y+++ +FVVI+K K+I+RF+ T A
Sbjct: 56 PDPRLEEGKKLSFLLGDCFSKKKFGGQLIDEIDPYYYDKRSFVVINKSKNIYRFTTTKAF 115
Query: 122 WILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFES 181
++ PFNP+R AI IL HPLFS+ ++ TI+ NCI+M + +++ E FT IY E
Sbjct: 116 FLFSPFNPVRTSAIKILTHPLFSIVVLLTIITNCIIMALNLD--IKALEQSFTIIYAAEF 173
Query: 182 AVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVT-MGIDLGNLAALRTFRVLRALKTVA 240
VK ARG I+ FTYLR WNWLDF+VI LAY+ + DLGN ++LRT RV RALKTV
Sbjct: 174 LVKAFARGLIINDFTYLRSIWNWLDFLVIGLAYLMFIEPDLGNYSSLRTLRVFRALKTVT 233
Query: 241 IVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWG 300
I+PG+ T+V A++ SV L+D I+LT+F L++FAL+GLQ+Y G LTQKCVK F D S
Sbjct: 234 ILPGMTTVVNALLNSVIKLKDAIVLTLFMLAIFALIGLQLYKGTLTQKCVKEF--DNSTM 291
Query: 301 NLTDEN----WER---FCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYG 353
NL DEN W+ F + NW+ + +C NS+ C PGY+C NPN+G
Sbjct: 292 NL-DENSTVAWDDIKIFYNSPENWH---EPHKVCSNST--APCPPGYLCFATSEGNPNFG 345
Query: 354 YTSFDTFGWAFLSAFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLILAI 402
+T++DTF WA+L AFRLMTQD+WE+LYQ FF+ +IF GSFYLVN+ILAI
Sbjct: 346 FTNYDTFPWAYLCAFRLMTQDFWEDLYQNTIRANGKIHVFFFMFVIFFGSFYLVNVILAI 405
Query: 403 VAMSY 407
VAMSY
Sbjct: 406 VAMSY 410
Score = 171 bits (416), Expect = 2e-40
Identities = 87/187 (46%), Positives = 115/187 (61%), Gaps = 5/187 (2%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L++ LRVFKLAKSW T+NLL +I+G T+GA+GNL VL II+FIFAV+GM F Y
Sbjct: 686 LRAFRLLRVFKLAKSWQTMNLLFTIIGHTVGAIGNLCIVLGIIVFIFAVLGMNTFHYGYQ 745
Query: 887 DYVDR--FPD--GDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVSCIPFFLAT 942
Y + +P+ G LPRWNF DF +SFMIVFRVLCGE+IESMWDC+ V + CIPFFL T
Sbjct: 746 KYRNTTLYPEFEGHLPRWNFDDFYNSFMIVFRVLCGEYIESMWDCLRVNNYLCIPFFLLT 805
Query: 943 VVIXXXXXXXXXXXXXXXXXXXXXXXTPTADQ-DTNKIAEAFNRISRFIDWIKRNVADFL 1001
+++ + + NK+ +AFNR+ R + +IK
Sbjct: 806 MILGNLVILNLFLALLISSFSSESLERREEESIEINKLQQAFNRVYRAVVFIKYKFVKLF 865
Query: 1002 KLLKNKL 1008
KL+K +L
Sbjct: 866 KLIKKRL 872
Score = 77.4 bits (182), Expect = 4e-12
Identities = 73/325 (22%), Positives = 148/325 (45%), Gaps = 41/325 (12%)
Query: 1478 DNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRW-RPQAIVFEIVTDK 1536
DN + +K+ E++ + +K +M K P + + Q V I+ D
Sbjct: 538 DNNEKIQKRRAAVFEIYEEKFKKSQRQLFFEMVEAKMCSWQFCPAYIKFQKCVSFIILDP 597
Query: 1537 KFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YF 1595
++ I L I N M L+ E+ + N F+ +F+ E + K AL YF
Sbjct: 598 FLELFITLCIVCNTCFMALEGPFTEESVKIFFRHSNYFFMGVFTFEAIGKQIALGLKTYF 657
Query: 1596 VEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLL 1655
E WN+FDF+VV+ S+L L + + + ++R ++ RV +L K + + L
Sbjct: 658 SERWNVFDFIVVIISLLELSRPNGV---------MSILRAFRLLRVFKLAKSWQTMNLLF 708
Query: 1656 FALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVY----------NFKTF 1705
+ ++ A+ N+C++L +++FIFA+ GM+ F + K +Y NF F
Sbjct: 709 TIIGHTVGAIGNLCIVLGIIVFIFAVLGMNTFHYGYQKYRNTTLYPEFEGHLPRWNFDDF 768
Query: 1706 VQSMILLFQMSTSAGWDGVLDGI-INEEECDLPDNERGSPGNCGSATIGITYLLSYLVIS 1764
S +++F++ + + D + +N C I + L +++
Sbjct: 769 YNSFMIVFRVLCGEYIESMWDCLRVNNYLC-------------------IPFFLLTMILG 809
Query: 1765 FLIVINMYIAVILENYSQATEDVQE 1789
L+++N+++A+++ ++S + + +E
Sbjct: 810 NLVILNLFLALLISSFSSESLERRE 834
Score = 77.4 bits (182), Expect = 4e-12
Identities = 42/170 (24%), Positives = 93/170 (54%), Gaps = 10/170 (5%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIM-----PTTPTVESTEVIFTGIYTFESAVK 184
IR + ++ H F FI+ I + + M + P P +E+T I ++T ++
Sbjct: 975 IRCLTFKVVDHKYFETFILFMIAFSSLTMTLEDKYLPNYPMLENTIYILDKVFTIVFLME 1034
Query: 185 VMARGFILQPFTYLRDAWNWLDFVVIALAYVT-MGIDLGN---LAALRTFRVLRALKTVA 240
++ + + + Y +D W+ LDF ++ +A ++ M D+ L A+RT R LR L+ ++
Sbjct: 1035 MLLKWMAIGLYKYFKDPWSCLDFAIVMIALISLMPFDMSRYDALKAMRTLRALRPLRAIS 1094
Query: 241 IVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCV 290
G++ +V A+I+++ ++ +V+++ + +F+++G+Q + G KC+
Sbjct: 1095 RWEGMRIVVNALIQAIPSIFNVMVVCLVFWLIFSIIGVQRFGGRF-YKCI 1143
Score = 74.9 bits (176), Expect = 2e-11
Identities = 50/185 (27%), Positives = 98/185 (52%), Gaps = 22/185 (11%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+R K++ + F V+ I+ + + +AL DI +++ FT+I+ E
Sbjct: 124 VRTSAIKILTHPLFSIVVLLTIITNCIIMALN----------LDIKA-LEQSFTIIYAAE 172
Query: 1267 MLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALR 1322
L+K A G Y + W WLDF+++ ++ + F+ G + ++RTLR R
Sbjct: 173 FLVKAFARGLIINDFTYLRSIWNWLDFLVIGLAYLMFIEPDLGN-----YSSLRTLRVFR 227
Query: 1323 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYF-KCV-DMN 1380
L+ ++ + GM VVNAL+ ++ + + +++ L IFA++G+QL+ G KCV + +
Sbjct: 228 ALKTVTILPGMTTVVNALLNSVIKLKDAIVLTLFMLAIFALIGLQLYKGTLTQKCVKEFD 287
Query: 1381 HTTLS 1385
++T++
Sbjct: 288 NSTMN 292
Score = 67.3 bits (157), Expect = 4e-09
Identities = 48/171 (28%), Positives = 85/171 (49%), Gaps = 18/171 (10%)
Query: 136 YILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVIFT-------GIYTFESAVKVMAR 188
+I++ P LFI I+ N M + T ES ++ F G++TFE+ K +A
Sbjct: 592 FIILDPFLELFITLCIVCNTCFMALEGPFTEESVKIFFRHSNYFFMGVFTFEAIGKQIAL 651
Query: 189 GFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTV---AIVPGL 245
G TY + WN DF+V+ ++ + + G ++ LR FR+LR K + L
Sbjct: 652 GLK----TYFSERWNVFDFIVVIISLLELSRPNGVMSILRAFRLLRVFKLAKSWQTMNLL 707
Query: 246 KTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQ-IYMGVLTQKCVKVFPE 295
TI+G + ++ NL V+ + +F +FA++G+ + G + ++PE
Sbjct: 708 FTIIGHTVGAIGNLCIVLGIIVF---IFAVLGMNTFHYGYQKYRNTTLYPE 755
Score = 63.7 bits (148), Expect = 5e-08
Identities = 27/60 (45%), Positives = 39/60 (65%)
Query: 773 CVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNY 832
C W C +++FQK V+ ++ DPF+ELFITLCIV NT FMAL+ ++ + + NY
Sbjct: 575 CSWQFCPAYIKFQKCVSFIILDPFLELFITLCIVCNTCFMALEGPFTEESVKIFFRHSNY 634
Score = 58.4 bits (135), Expect = 2e-06
Identities = 41/162 (25%), Positives = 76/162 (46%), Gaps = 8/162 (4%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
+I + + E + I+ ++ +ALE ++ + + F +F E + K +A
Sbjct: 593 IILDPFLELFITLCIVCNTCFMALEGPFTEES--VKIFFRHSNYFFMGVFTFEAIGKQIA 650
Query: 1274 LGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGM 1333
LG + YF+ W DFI+V++SL+ L G+ + +R R LR + Q M
Sbjct: 651 LGLKTYFSERWNVFDFIVVIISLLE----LSRPNGVMSI--LRAFRLLRVFKLAKSWQTM 704
Query: 1334 RVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK 1375
++ + + +I N+ +V I IFA++G+ F Y K
Sbjct: 705 NLLFTIIGHTVGAIGNLCIVLGIIVFIFAVLGMNTFHYGYQK 746
Score = 49.6 bits (113), Expect = 9e-04
Identities = 38/151 (25%), Positives = 72/151 (47%), Gaps = 17/151 (11%)
Query: 146 FIITTILVNCI-LMIMPT--TPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAW 202
FI+ L CI P T ++ +F I+ E +K++ GF + Y +D W
Sbjct: 1316 FIVLNTLTMCIEFQDQPKLLTRVLDIVGRVFLLIFAGEFIMKLI--GF---RWFYFKDPW 1370
Query: 203 NWLDFVVIALAYVT---------MGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVI 253
N DF V+ + + +D + +R FR+ R L+ V G++T++ +++
Sbjct: 1371 NVFDFSVVVFSTIAWILQFFESIFPLDPTLIRIVRLFRITRVLRLVKSARGIRTLLFSLV 1430
Query: 254 ESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
S+ L ++ +L M + ++A+MGL + V
Sbjct: 1431 VSLPALFNIALLLMLVMFIYAIMGLSFFANV 1461
Score = 47.2 bits (107), Expect = 0.005
Identities = 55/199 (27%), Positives = 92/199 (46%), Gaps = 29/199 (14%)
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL 1590
+I+T F ++++L I N + M L+ + L F +I+++E L+K FA
Sbjct: 130 KILTHPLFSIVVLLTIITNCIIMALN---------LDIKALEQSFTIIYAAEFLVKAFAR 180
Query: 1591 R-----YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLV 1645
+ Y WN DF+V+ + L + D + Y + LR +RV R L+ V
Sbjct: 181 GLIINDFTYLRSIWNWLDFLVIGLAYLMFIEPD-LGNY----SSLRTLRVF---RALKTV 232
Query: 1646 KGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTF 1705
G+ T++ AL S+ L + +L ++ IFA+ G+ + KG L K F
Sbjct: 233 TILPGMTTVVNALLNSVIKLKDAIVLTLFMLAIFALIGLQLY-----KGTLTQKC-VKEF 286
Query: 1706 VQSMILLFQMSTSAGWDGV 1724
S + L + ST A WD +
Sbjct: 287 DNSTMNLDENSTVA-WDDI 304
Score = 44.0 bits (99), Expect = 0.042
Identities = 34/130 (26%), Positives = 65/130 (50%), Gaps = 10/130 (7%)
Query: 792 VFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISI 851
VFD V +F T+ ++ F ++ +D + + ++ RV +L KS + L+
Sbjct: 1372 VFDFSVVVFSTIAWILQ-FFESI--FPLDPTLIRIVRLFRITRVLRLVKSARGIRTLLFS 1428
Query: 852 MGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMI 911
+ ++ AL N+ +L +++FI+A+MG+ F Y G +NF F +S +I
Sbjct: 1429 LVVSLPALFNIALLLMLVMFIYAIMGLSFFANVPHKY------GIDETFNFETFFNSMII 1482
Query: 912 VFRV-LCGEW 920
+F++ G W
Sbjct: 1483 LFQISTTGGW 1492
>UniRef50_UPI0000E48802 Cluster: PREDICTED: similar to CG9071-PA; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
CG9071-PA - Strongylocentrotus purpuratus
Length = 1880
Score = 688 bits (1701), Expect = 0.0
Identities = 338/712 (47%), Positives = 472/712 (66%), Gaps = 13/712 (1%)
Query: 1169 DEDVVDDTPADCCPEQC---YQK----FPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFE 1221
+E +++D DC P C Y K P ++S + W R F + E+ FE
Sbjct: 1001 EEPILEDPVKDCLPRLCASFYAKKCSCIPCCLDANESNWAYRWRRYREIMFTVCEHKVFE 1060
Query: 1222 TAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFT 1281
T +I +I SS L ED++L P Q+IL ++ +F IF +EMLIKW GF KYFT
Sbjct: 1061 TFIIVVIFGSSFTLIFEDIYLDLHPRRQEILKILNYVFFGIFVVEMLIKWSGYGFVKYFT 1120
Query: 1282 NAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALV 1341
+ WCWLDF IV+V L++ + + G AF+ +RTLRALRPLRA+SR +GM++VVNA+V
Sbjct: 1121 SFWCWLDFCIVLVGLLSLLGDVIGLTNFAAFRALRTLRALRPLRAISRWEGMKIVVNAVV 1180
Query: 1342 QAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYT 1401
AIPSI NVLLVC + WLIF+IMGV F G + +CVD L H I+ +K+ C +NY+
Sbjct: 1181 HAIPSIANVLLVCAMIWLIFSIMGVLFFKGVFDRCVDEFGDRLLHTIVNNKSECLEKNYS 1240
Query: 1402 WENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSR--EVGRQPIRETNIYMYLYXXX 1459
WE P+NF++VG Y+ LFQV TF+GW++ M A+DSR QPI++ Y Y+Y
Sbjct: 1241 WETPPINFNNVGLGYVALFQVTTFEGWMEAMAAAVDSRGSRENLQPIKDNRFYYYVYFVI 1300
Query: 1460 XXXXXXXXTLNLFIGVIIDNFNEQKKKAGG--SLEMFMTEDQKKYYNAMKKMGSKKPLKA 1517
LNLFIGVIIDNFN K+K G S++M ++ QK+YY M++MG KKP K
Sbjct: 1301 LIVFGSFFLLNLFIGVIIDNFNALKRKYEGDSSMDMLLSTSQKQYYQTMRRMGVKKPTKQ 1360
Query: 1518 IPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIV 1577
I +P + Q + + T KF+++I+ I +NM+ M +DHY S+ + + N++F
Sbjct: 1361 IKQPTNKIQNFFYRLTTSNKFELVIVTVIVMNMILMMIDHYGMSQELTDITAKFNIVFTS 1420
Query: 1578 IFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAK 1637
IF E +LK+ ++YF PWN+FD +VV+FS+L +VL D++ F++PTLLRV+R+ +
Sbjct: 1421 IFVCEAVLKLIGYSWYYFKIPWNVFDIIVVIFSVLGIVLDDVLNSVFINPTLLRVLRLFR 1480
Query: 1638 VGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLD 1697
+GRVLRLVK AKGIR LLFAL +SLPAL NI +LL LV+F+F+I GMS F H+K G LD
Sbjct: 1481 IGRVLRLVKQAKGIRKLLFALVISLPALLNIGILLLLVIFVFSIIGMSQFGHIKLDGALD 1540
Query: 1698 DVYNFKTFVQSMILLFQMSTSAGWDGVLDGI-INEEECDLPDNERGSPGNCGSATIGITY 1756
NF+T+V S +LLF++STSAGW+ VLD + I E +CD P+ E GNCG I I +
Sbjct: 1541 KTTNFQTWVNSALLLFRLSTSAGWNDVLDPMMIQEPDCD-PNFEGLPNGNCGGFYIPIFF 1599
Query: 1757 LLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRY 1816
YLVI+FL+VIN YIAVILEN+SQA + G+T+DD+ M+Y+IW+++DP SQ+I+Y
Sbjct: 1600 STVYLVITFLVVINTYIAVILENFSQAHAQEEVGITEDDFGMFYQIWEKYDPSASQFIKY 1659
Query: 1817 DQLSDFLDVLEPPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTKDFFA 1868
+QLS+F D LE PL++ +PN+ KI ++D+PI G + C+D+L ALTK A
Sbjct: 1660 EQLSEFCDALELPLRLARPNRIKIAALDMPIYDGFRLHCLDVLFALTKRVLA 1711
Score = 253 bits (619), Expect = 4e-65
Identities = 124/256 (48%), Positives = 169/256 (66%), Gaps = 22/256 (8%)
Query: 172 IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMG-----IDLGNLAA 226
IFT IY+ E VK+ ARGF L P TY+RDAWNWLDF VI LAY+T G +D+GN
Sbjct: 140 IFTTIYSVEMFVKIFARGFALHPHTYMRDAWNWLDFFVIVLAYITFGLVESGVDIGNFNF 199
Query: 227 LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLT 286
LRTFRVLRALKT+++VPGLK+I+ A+I S K L +V++LT+F+L + AL+ LQ++MG LT
Sbjct: 200 LRTFRVLRALKTISVVPGLKSIINALIRSTKMLGEVMLLTVFALCIIALLALQLFMGKLT 259
Query: 287 QKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQ----CEPGYVC 342
+KCV P N++DE + F Q+ NW D +C N + G+ C Y C
Sbjct: 260 RKCVANIPPVDF--NISDEYFFNFTQDPANWLTWNSDPVICSNMTLGGRDWSLCPENYTC 317
Query: 343 LQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ-----------LFFVVIIFLG 391
L+G G NPN GYT+FD G++ L+ F+L+T DYWEN+Y FF+ + G
Sbjct: 318 LEGIGDNPNDGYTNFDNIGYSMLTCFQLITLDYWENVYNNILKAQGPYAVFFFLTTVMFG 377
Query: 392 SFYLVNLILAIVAMSY 407
+FYL+NL+LA+V+M+Y
Sbjct: 378 AFYLINLMLAVVSMAY 393
Score = 126 bits (305), Expect = 5e-27
Identities = 64/171 (37%), Positives = 97/171 (56%), Gaps = 3/171 (1%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+S LRV KLA+SW T+ L+SI+ + A+GN+ VL I++FIFAV+GMQ+ G +Y
Sbjct: 626 LRSFRLLRVLKLAQSWTTMRTLLSIIASAITAIGNVMIVLLIVMFIFAVIGMQILGGSYT 685
Query: 887 -DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVS-CIPFFLATVV 944
+ ++P W F DF HS M++FR+LCGEWIE ++DCM VG+ C+ F+AT++
Sbjct: 686 PENFGVATFEEIPPWTFQDFQHSIMLIFRILCGEWIEPLYDCMNVGNKPFCVILFIATLI 745
Query: 945 IXXXXXXXXXXXXXXXXXXXXXXXTPTADQDTNKIAEAFNRISRFIDWIKR 995
+ A + +K+ AF +I RF+ + R
Sbjct: 746 VGNIMMLNLFLALLLNSFASDSLQNKKAASE-SKLILAFRKIGRFLKCLVR 795
Score = 103 bits (248), Expect = 4e-20
Identities = 72/268 (26%), Positives = 141/268 (52%), Gaps = 33/268 (12%)
Query: 1522 RWRP-QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFS 1580
RWR Q I +V D D+ I L I N + +DH + S++ + + + N +F IF+
Sbjct: 522 RWRKVQYIASWVVLDPLMDLFITLCILGNTAFLMMDHEEISDSLAYISEEGNKVFTYIFT 581
Query: 1581 SECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGR 1640
EC+LK+ AL +F PWN+FD VV S+L L+++ L V+R ++ R
Sbjct: 582 IECVLKLIALDKKFFKNPWNVFDLFVVCVSLLEFGLANV--------EGLSVLRSFRLLR 633
Query: 1641 VLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF--MHVKDKGGL-- 1696
VL+L + +RTLL +A ++ A+ N+ ++L +VMFIFA+ GM + + G+
Sbjct: 634 VLKLAQSWTTMRTLLSIIASAITAIGNVMIVLLIVMFIFAVIGMQILGGSYTPENFGVAT 693
Query: 1697 -DDV--YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIG 1753
+++ + F+ F S++L+F++ + + D + N G+
Sbjct: 694 FEEIPPWTFQDFQHSIMLIFRILCGEWIEPLYDCM-----------------NVGNKPFC 736
Query: 1754 ITYLLSYLVISFLIVINMYIAVILENYS 1781
+ ++ L++ ++++N+++A++L +++
Sbjct: 737 VILFIATLIVGNIMMLNLFLALLLNSFA 764
Score = 87.0 bits (206), Expect = 5e-15
Identities = 79/300 (26%), Positives = 136/300 (45%), Gaps = 49/300 (16%)
Query: 1225 ITMILLSSLALALEDVHLPHRPILQDILYYMD---RIFTVIFFIEMLIKWLALGFQKYFT 1281
IT+ +L + A + D H I + Y + ++FT IF IE ++K +AL +K+F
Sbjct: 543 ITLCILGNTAFLMMD----HEEISDSLAYISEEGNKVFTYIFTIECVLKLIALD-KKFFK 597
Query: 1282 NAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALV 1341
N W D +V VSL+ F G ++ +R+ R LR L+ MR +++ +
Sbjct: 598 NPWNVFDLFVVCVSLLEF-----GLANVEGLSVLRSFRLLRVLKLAQSWTTMRTLLSIIA 652
Query: 1342 QAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYT 1401
AI +I NV++V LI IFA++G+Q+ G Y N + E IP
Sbjct: 653 SAITAIGNVMIVLLIVMFIFAVIGMQILGGSY---TPENFGVATFEEIP----------- 698
Query: 1402 WENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXX 1461
P F + + +F++ + WI+ + D ++ VG +P + +
Sbjct: 699 ----PWTFQDFQHSIMLIFRILCGE-WIEPLYDCMN---VGNKP------FCVILFIATL 744
Query: 1462 XXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRP 1521
LNLF+ +++++F A SL+ + K A +K+G + LK + RP
Sbjct: 745 IVGNIMMLNLFLALLLNSF------ASDSLQNKKAASESKLILAFRKIG--RFLKCLVRP 796
Score = 83.8 bits (198), Expect = 4e-14
Identities = 45/125 (36%), Positives = 72/125 (57%), Gaps = 6/125 (4%)
Query: 1258 IFTVIFFIEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFK 1313
IFT I+ +EM +K A GF Y +AW WLDF +++++ I F G I F
Sbjct: 140 IFTTIYSVEMFVKIFARGFALHPHTYMRDAWNWLDFFVIVLAYITFGLVESGV-DIGNFN 198
Query: 1314 TMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
+RT R LR L+ +S + G++ ++NAL+++ + V+L+ + I A++ +QLF GK
Sbjct: 199 FLRTFRVLRALKTISVVPGLKSIINALIRSTKMLGEVMLLTVFALCIIALLALQLFMGKL 258
Query: 1374 F-KCV 1377
KCV
Sbjct: 259 TRKCV 263
Score = 81.0 bits (191), Expect = 3e-13
Identities = 80/297 (26%), Positives = 136/297 (45%), Gaps = 50/297 (16%)
Query: 131 RRVAIYILVHPLFSLFIITTILVNCILMIM--------PTTPTV-ESTEVIFTGIYTFES 181
R + + H +F FII I + +I P + + +F GI+ E
Sbjct: 1047 REIMFTVCEHKVFETFIIVVIFGSSFTLIFEDIYLDLHPRRQEILKILNYVFFGIFVVEM 1106
Query: 182 AVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM---GIDLGNLAA---LRTFRVLRA 235
+K GF+ Y W WLDF ++ + +++ I L N AA LRT R LR
Sbjct: 1107 LIKWSGYGFV----KYFTSFWCWLDFCIVLVGLLSLLGDVIGLTNFAAFRALRTLRALRP 1162
Query: 236 LKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPE 295
L+ ++ G+K +V AV+ ++ ++ +V+++ +F++MG+ + GV +CV F
Sbjct: 1163 LRAISRWEGMKIVVNAVVHAIPSIANVLLVCAMIWLIFSIMGVLFFKGVF-DRCVDEF-- 1219
Query: 296 DGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYT 355
G T N + C E N+ E P+ N+ G GYV L + T
Sbjct: 1220 -GDRLLHTIVNNKSECL-EKNYSWE--TPPINFNNVGL-----GYVAL--------FQVT 1262
Query: 356 SFDTFGWAFLSAFRLMTQDYWENL---------YQLFFVVIIFLGSFYLVNLILAIV 403
+F+ GW A + ++ ENL Y ++FV++I GSF+L+NL + ++
Sbjct: 1263 TFE--GWMEAMAAAVDSRGSRENLQPIKDNRFYYYVYFVILIVFGSFFLLNLFIGVI 1317
Score = 70.1 bits (164), Expect = 6e-10
Identities = 47/180 (26%), Positives = 92/180 (51%), Gaps = 15/180 (8%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVI-------FTGIYTFESA 182
++ +A ++++ PL LFI IL N ++M +S I FT I+T E
Sbjct: 526 VQYIASWVVLDPLMDLFITLCILGNTAFLMMDHEEISDSLAYISEEGNKVFTYIFTIECV 585
Query: 183 VKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGNLAALRTFRVLRALKTVAI 241
+K++A + ++ WN D V+ ++ + G+ ++ L+ LR+FR+LR LK
Sbjct: 586 LKLIALDK-----KFFKNPWNVFDLFVVCVSLLEFGLANVEGLSVLRSFRLLRVLKLAQS 640
Query: 242 VPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQK--CVKVFPEDGSW 299
++T++ + ++ + +V+I+ + + +FA++G+QI G T + V F E W
Sbjct: 641 WTTMRTLLSIIASAITAIGNVMIVLLIVMFIFAVIGMQILGGSYTPENFGVATFEEIPPW 700
Score = 56.4 bits (130), Expect = 7e-06
Identities = 28/73 (38%), Positives = 42/73 (57%), Gaps = 4/73 (5%)
Query: 64 DATLEQGLPLPVRMQGSFPLELASTPLEDIDPFYHNQTTFVVIS---KGKDIFRFSATNA 120
D+ G P ++ G FP +L STP+E++DP +FVV+ K IFRF+ +A
Sbjct: 69 DSDFASGSVCPFKL-GPFPRKLLSTPIEELDPARQEDRSFVVVGRKFKTSQIFRFTTNDA 127
Query: 121 LWILDPFNPIRRV 133
L+ L P NP+R +
Sbjct: 128 LYCLSPLNPLRYI 140
Score = 56.0 bits (129), Expect = 1e-05
Identities = 44/172 (25%), Positives = 85/172 (49%), Gaps = 21/172 (12%)
Query: 123 ILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM-------PTTPTVESTEVIFTG 175
I P N I+ + F L I+T I++N ILM++ T ++FT
Sbjct: 1361 IKQPTNKIQNFFYRLTTSNKFELVIVTVIVMNMILMMIDHYGMSQELTDITAKFNIVFTS 1420
Query: 176 IYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID--LGN-------LAA 226
I+ E+ +K++ G+ + Y + WN D +V+ + + + +D L + L
Sbjct: 1421 IFVCEAVLKLI--GY---SWYYFKIPWNVFDIIVVIFSVLGIVLDDVLNSVFINPTLLRV 1475
Query: 227 LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGL 278
LR FR+ R L+ V G++ ++ A++ S+ L ++ IL + + VF+++G+
Sbjct: 1476 LRLFRIGRVLRLVKQAKGIRKLLFALVISLPALLNIGILLLLVIFVFSIIGM 1527
Score = 55.2 bits (127), Expect = 2e-05
Identities = 51/204 (25%), Positives = 90/204 (44%), Gaps = 12/204 (5%)
Query: 1492 EMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNML 1551
EM ++ Y++ GS P K P PR + E+ ++ D ++ +G
Sbjct: 57 EMEEKRGKESEYDSDFASGSVCPFKLGPFPRKLLSTPIEELDPARQEDRSFVV-VGRKFK 115
Query: 1552 TMTLDHYQQSETFSAV--LDYLNMIFIVIFSSECLLKI----FALRYH-YFVEPWNLFDF 1604
T + + ++ + L+ L IF I+S E +KI FAL H Y + WN DF
Sbjct: 116 TSQIFRFTTNDALYCLSPLNPLRYIFTTIYSVEMFVKIFARGFALHPHTYMRDAWNWLDF 175
Query: 1605 VVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPA 1664
V+ +L+ + ++E V +R +V R L+ + G+++++ AL S
Sbjct: 176 FVI---VLAYITFGLVES-GVDIGNFNFLRTFRVLRALKTISVVPGLKSIINALIRSTKM 231
Query: 1665 LFNICLLLFLVMFIFAIFGMSFFM 1688
L + LL + I A+ + FM
Sbjct: 232 LGEVMLLTVFALCIIALLALQLFM 255
Score = 50.8 bits (116), Expect = 4e-04
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 4/112 (3%)
Query: 770 DFFCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKS 829
+F C + W + Q + +V DP ++LFITLCI+ NT F+ +DH + + +
Sbjct: 512 NFICTFPHYRRWRKVQYIASWVVLDPLMDLFITLCILGNTAFLMMDHEEISDSLAYISEE 571
Query: 830 GNYLRVFKLAKSWPTLNLLISIMGRTMGALGNL--TFVLCIIIFIFAVMGMQ 879
GN +VF + + LI++ + N+ FV+C+ + F + ++
Sbjct: 572 GN--KVFTYIFTIECVLKLIALDKKFFKNPWNVFDLFVVCVSLLEFGLANVE 621
Score = 49.2 bits (112), Expect = 0.001
Identities = 39/149 (26%), Positives = 76/149 (51%), Gaps = 11/149 (7%)
Query: 792 VFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISI 851
VFD V +F L IV++ + ++ + + + + G LR+ K AK + L+
Sbjct: 1444 VFDIIVVIFSVLGIVLDDVLNSVFINPTLLRVLRLFRIGRVLRLVKQAKG---IRKLLFA 1500
Query: 852 MGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPR-WNFTDFMHSFM 910
+ ++ AL N+ +L ++IF+F+++GM FG + DG L + NF +++S +
Sbjct: 1501 LVISLPALLNIGILLLLVIFVFSIIGMSQFGHIKL-------DGALDKTTNFQTWVNSAL 1553
Query: 911 IVFRVLCGEWIESMWDCMLVGDVSCIPFF 939
++FR+ + D M++ + C P F
Sbjct: 1554 LLFRLSTSAGWNDVLDPMMIQEPDCDPNF 1582
>UniRef50_Q05973 Cluster: Sodium channel protein I, brain; n=1; Loligo
bleekeri|Rep: Sodium channel protein I, brain - Loligo
bleekeri (Bleeker's squid)
Length = 1522
Score = 688 bits (1700), Expect = 0.0
Identities = 352/781 (45%), Positives = 514/781 (65%), Gaps = 30/781 (3%)
Query: 1157 GTLGKT-DIKVGA--DEDVVDDTPAD---CCPEQCYQKFPFLAGDDDSPFWQGWGTLRLK 1210
G+LG DI G+ ++D+ D C P +F L DD+ + W R +
Sbjct: 715 GSLGSIPDIMDGSSVEDDISSCQQKDIQPCLPLFISSRFKCLREFDDTSHGKKWNNFRRQ 774
Query: 1211 TFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIK 1270
+ EN YFET V+ +I SS+ LA ED++L +P L+ ++Y+D F ++FF+EM++K
Sbjct: 775 LMMVCENKYFETGVLVIIFASSILLAFEDIYLNEKPRLKLAIFYLDITFCLLFFLEMVLK 834
Query: 1271 WLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRM 1330
+ALGF Y+T+ W LDF IV++++I+ A+ G I AF+++RTLRALRPLRA+SR
Sbjct: 835 LVALGFVHYYTHFWTILDFTIVIITVISLAASGLGMEQITAFRSLRTLRALRPLRAVSRW 894
Query: 1331 QGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIP 1390
QGM+++VNAL+ +IPSIFNVLLVC++FWLIFAIMGVQLFAGK++KCV+ + + +
Sbjct: 895 QGMKIIVNALMLSIPSIFNVLLVCVVFWLIFAIMGVQLFAGKFYKCVNETNMRIPPTEVA 954
Query: 1391 DKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETN 1450
+K C +NYTW NS +NFD+VG A+L LFQVATF+GW++IM DA+D EV QP E
Sbjct: 955 NKIECYNKNYTWVNSNVNFDNVGGAFLALFQVATFEGWMEIMADAVDVTEVDEQPKFEAT 1014
Query: 1451 IYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGS-LEMFMTEDQKKYYNAMKKM 1509
+Y Y Y LNL IGVIID F+ KKK G+ L+MF+T Q+ YYN +KK+
Sbjct: 1015 VYYYFYFVLFIIFGSFFVLNLVIGVIIDKFSFLKKKYDGTYLDMFLTPTQQNYYNTLKKL 1074
Query: 1510 GSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLD 1569
G+KKP K + RP+ + QA+V+++V +F++ I I NM+ M +HY QSE + VL
Sbjct: 1075 GTKKPQKTVKRPKNKCQAVVYDLVMSNQFEIFITTIIITNMIFMAFEHYNQSEVVTEVLA 1134
Query: 1570 YLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDII-EKYFVSPT 1628
N+ F ++++ E ++KI LR HY WN+FDF+VV S++ L+DI + F++P+
Sbjct: 1135 TANIAFTILYAVEAIIKIIGLRIHYLRNLWNVFDFLVVTLSVMDAFLNDIFGDGIFMNPS 1194
Query: 1629 LLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
LLRV R+ ++GR++RL+K AKG+R LLFAL +SLPALFNI LL LVMFI+ I GMS F
Sbjct: 1195 LLRVARMFRIGRIIRLIKWAKGMRKLLFALVISLPALFNIGALLMLVMFIYTIIGMSSFG 1254
Query: 1689 HVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDG-IINEEECD-------LPDNE 1740
+K G L+D NF+TF ++ +LL +++TSAGW+ +L +I CD +
Sbjct: 1255 QIKLSGALNDQVNFQTFGKTFLLLVRLATSAGWNDILGPLLIQPPNCDPNYITTSTGEKI 1314
Query: 1741 RGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYY 1800
+ G+CG + I+Y++SY++I F+IV NMYIAVILEN++QA + G+T+DD DM+Y
Sbjct: 1315 KVVNGDCGMPWLAISYMVSYIIIVFMIVFNMYIAVILENFNQAHAQEEVGITEDDLDMFY 1374
Query: 1801 EIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHKPNKYKIISMDIPICRGDMMFCVDILD 1860
+W+++DP +Q+I+++QLSDF+ L+PPL++ KPN I + D+PI +G + C+DIL
Sbjct: 1375 GVWEQYDPLATQFIKHEQLSDFIQDLDPPLKVKKPNNVAIATFDLPIVKGGHIHCLDILL 1434
Query: 1861 ALTKDFFARKGNPIEETGDLEVGRPE-EAGYEPV----------SSTLWRQREEYCARLI 1909
AL K FA GN +EET + R + EA ++ + +STL +REE AR +
Sbjct: 1435 ALVK--FALGGN-LEETEAFKRVRTQMEARFDEIFPTREKSEIRTSTLQMRREEMAARTL 1491
Query: 1910 Q 1910
Q
Sbjct: 1492 Q 1492
Score = 299 bits (733), Expect = 6e-79
Identities = 148/327 (45%), Positives = 214/327 (65%), Gaps = 23/327 (7%)
Query: 102 TFVVISKG--KDIF-RFSATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILM 158
TFVVI K K+I RFSA +L++ P NPIRR+A+ I + F F++ TI++NC+ +
Sbjct: 13 TFVVIEKRFKKNIIHRFSAKRSLFLFTPRNPIRRLAVCIATNVCFDYFLMFTIMINCVFL 72
Query: 159 IMPTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMG 218
MP E E IF GIYT E A+K++A GF + +TYLRDAWN LDF VI ++Y+T+
Sbjct: 73 AMPDIS--EFAEYIFLGIYTMEMAIKLVAGGFFIDKYTYLRDAWNCLDFTVIMISYITLL 130
Query: 219 ID------LGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSV 272
+ + ++ LRTFRVLRAL+T++I+PGLKT+V A++ +++ L V+IL +F L +
Sbjct: 131 LQTINDKVISDITGLRTFRVLRALRTLSIIPGLKTMVNALLRALRMLISVLILILFCLWI 190
Query: 273 FALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEG-GDYPLCGNSS 331
F+ G+Q++ G L KCV ++G DE + +N NW +G G+Y LCGN++
Sbjct: 191 FSQAGVQLFGGALRHKCVLQIHGSPAFGKTYDEFYAEHIENSDNWLAKGNGEYVLCGNAT 250
Query: 332 GAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ---------- 381
GAG C Y CL G NPNYGYT+FD+ GW+ L +F+L+TQDYWE++Y
Sbjct: 251 GAGPCPTNYTCLPDIGENPNYGYTNFDSIGWSMLISFQLLTQDYWEDVYNKVIRAHSPWT 310
Query: 382 -LFFVVIIFLGSFYLVNLILAIVAMSY 407
++F+VI F GS YL+NL+LA+VA +Y
Sbjct: 311 VIYFIVINFFGSLYLMNLMLAVVATAY 337
Score = 132 bits (319), Expect = 9e-29
Identities = 61/117 (52%), Positives = 80/117 (68%), Gaps = 2/117 (1%)
Query: 828 KSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVD 887
+S LRVF LA+SW T+ LL+ I+ T+G+LG LT +L I+I+IFAV G+QLF Y
Sbjct: 501 RSFRLLRVFHLAQSWTTMRLLLCIILNTLGSLGYLTIILIIVIYIFAVTGLQLFHTEYTP 560
Query: 888 YVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVSCIPFFLATVV 944
D+F +PRWNF DF+HSFM+VFR+LCGEWIE M+DCM + C F+ V
Sbjct: 561 --DKFRGEPVPRWNFNDFLHSFMMVFRILCGEWIEPMYDCMRACNGLCFLIFIPVTV 615
Score = 86.2 bits (204), Expect = 8e-15
Identities = 78/330 (23%), Positives = 143/330 (43%), Gaps = 40/330 (12%)
Query: 1408 NFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXX 1467
NFD +G + L FQ+ T W + N I R + + +Y
Sbjct: 275 NFDSIGWSMLISFQLLTQDYWEDVYNKVI----------RAHSPWTVIYFIVINFFGSLY 324
Query: 1468 TLNLFIGVIIDNFNEQKKKAGGSL--------EMFMTEDQKKYYNAMKKMGS-------- 1511
+NL + V+ + + K G L E + E +++ + + S
Sbjct: 325 LMNLMLAVVATAYELEVKNTGKKLQQTAATAREQSLKEQERRNTLTVSEADSHVDDRNCT 384
Query: 1512 --KKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLD 1569
++ P R Q+ I+TD ++ I+ I LN + + ++H+ S VL
Sbjct: 385 CCEQCCGCCYNPWLRVQSFAHCIITDSFTEVFIIFIIVLNTVFLAMEHHGMSMELKNVLK 444
Query: 1570 YLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTL 1629
N +F +F E +LK+ A YF WN+ D VVV+ S++ L + +
Sbjct: 445 VANYVFTTVFVLEAILKLLAFNKQYFKSGWNICDLVVVVASLIDLGVEGL--------KG 496
Query: 1630 LRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF-- 1687
+ V R ++ RV L + +R LL + +L +L + ++L +V++IFA+ G+ F
Sbjct: 497 VSVFRSFRLLRVFHLAQSWTTMRLLLCIILNTLGSLGYLTIILIIVIYIFAVTGLQLFHT 556
Query: 1688 MHVKDKGGLDDV--YNFKTFVQSMILLFQM 1715
+ DK + V +NF F+ S +++F++
Sbjct: 557 EYTPDKFRGEPVPRWNFNDFLHSFMMVFRI 586
Score = 83.8 bits (198), Expect = 4e-14
Identities = 51/139 (36%), Positives = 76/139 (54%), Gaps = 5/139 (3%)
Query: 1248 LQDILYYMDRIFTVIFFIEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAAL 1303
+ DI + + IF I+ +EM IK +A GF Y +AW LDF ++M+S I +
Sbjct: 74 MPDISEFAEYIFLGIYTMEMAIKLVAGGFFIDKYTYLRDAWNCLDFTVIMISYITLLLQT 133
Query: 1304 CGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAI 1363
I +RT R LR LR +S + G++ +VNAL++A+ + +VL++ L IF+
Sbjct: 134 INDKVISDITGLRTFRVLRALRTLSIIPGLKTMVNALLRALRMLISVLILILFCLWIFSQ 193
Query: 1364 MGVQLFAGKY-FKCVDMNH 1381
GVQLF G KCV H
Sbjct: 194 AGVQLFGGALRHKCVLQIH 212
Score = 77.8 bits (183), Expect = 3e-12
Identities = 60/215 (27%), Positives = 109/215 (50%), Gaps = 24/215 (11%)
Query: 1161 KTDIKVGADEDVVDDTPADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFK--LIENT 1218
+ + V + VDD CC EQC G +P W LR+++F +I ++
Sbjct: 366 RNTLTVSEADSHVDDRNCTCC-EQC-------CGCCYNP----W--LRVQSFAHCIITDS 411
Query: 1219 YFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQK 1278
+ E +I +I+L+++ LA+E H L+++L + +FT +F +E ++K LA Q
Sbjct: 412 FTEVFIIFIIVLNTVFLAME--HHGMSMELKNVLKVANYVFTTVFVLEAILKLLAFNKQ- 468
Query: 1279 YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVN 1338
YF + W D ++V+ SLI+ G G++ R+ R LR MR+++
Sbjct: 469 YFKSGWNICDLVVVVASLIDL-----GVEGLKGVSVFRSFRLLRVFHLAQSWTTMRLLLC 523
Query: 1339 ALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
++ + S+ + ++ +I IFA+ G+QLF +Y
Sbjct: 524 IILNTLGSLGYLTIILIIVIYIFAVTGLQLFHTEY 558
Score = 69.7 bits (163), Expect = 7e-10
Identities = 52/211 (24%), Positives = 102/211 (48%), Gaps = 18/211 (8%)
Query: 1482 EQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMI 1541
++K A + F+ +++ N + + +K+ L PR + + I T+ FD
Sbjct: 2 DEKYTAKNRDKTFVVIEKRFKKNIIHRFSAKRSLFLFT-PRNPIRRLAVCIATNVCFDYF 60
Query: 1542 IMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKI-----FALRYHYFV 1596
+M I +N + + + + ++ IF+ I++ E +K+ F +Y Y
Sbjct: 61 LMFTIMINCVFLAMPD---------ISEFAEYIFLGIYTMEMAIKLVAGGFFIDKYTYLR 111
Query: 1597 EPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLF 1656
+ WN DF V+M S ++L+L I +K T LR RV + R L ++ G++T++
Sbjct: 112 DAWNCLDFTVIMISYITLLLQTINDKVISDITGLRTFRVLRALRTLSII---PGLKTMVN 168
Query: 1657 ALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
AL +L L ++ +L+ ++IF+ G+ F
Sbjct: 169 ALLRALRMLISVLILILFCLWIFSQAGVQLF 199
Score = 63.7 bits (148), Expect = 5e-08
Identities = 36/127 (28%), Positives = 72/127 (56%), Gaps = 11/127 (8%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM---GIDLGNLAA 226
++ F ++ E +K++A GF+ Y W LDF ++ + +++ G+ + + A
Sbjct: 820 DITFCLLFFLEMVLKLVALGFV----HYYTHFWTILDFTIVIITVISLAASGLGMEQITA 875
Query: 227 LRTFRVLRALKTVAIVP---GLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
R+ R LRAL+ + V G+K IV A++ S+ ++ +V+++ + +FA+MG+Q++ G
Sbjct: 876 FRSLRTLRALRPLRAVSRWQGMKIIVNALMLSIPSIFNVLLVCVVFWLIFAIMGVQLFAG 935
Query: 284 VLTQKCV 290
KCV
Sbjct: 936 KF-YKCV 941
Score = 58.0 bits (134), Expect = 2e-06
Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 1/58 (1%)
Query: 777 CCWL-WLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYL 833
CC+ WL Q + ++ D F E+FI IV+NT+F+A++HH M ++ LK NY+
Sbjct: 392 CCYNPWLRVQSFAHCIITDSFTEVFIIFIIVLNTVFLAMEHHGMSMELKNVLKVANYV 449
Score = 57.2 bits (132), Expect = 4e-06
Identities = 39/166 (23%), Positives = 83/166 (50%), Gaps = 16/166 (9%)
Query: 127 FNPIRRVAIY---ILVHPLFSLFIITTILVNCIL-------MIMPTTPTVESTEVIFTGI 176
+NP RV + I+ +FII I++N + M M ++ +FT +
Sbjct: 394 YNPWLRVQSFAHCIITDSFTEVFIIFIIVLNTVFLAMEHHGMSMELKNVLKVANYVFTTV 453
Query: 177 YTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID-LGNLAALRTFRVLRA 235
+ E+ +K++A F Q Y + WN D VV+ + + +G++ L ++ R+FR+LR
Sbjct: 454 FVLEAILKLLA--FNKQ---YFKSGWNICDLVVVVASLIDLGVEGLKGVSVFRSFRLLRV 508
Query: 236 LKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
++ ++ ++ ++ +L + I+ + + +FA+ GLQ++
Sbjct: 509 FHLAQSWTTMRLLLCIILNTLGSLGYLTIILIIVIYIFAVTGLQLF 554
Score = 53.2 bits (122), Expect = 7e-05
Identities = 40/173 (23%), Positives = 83/173 (47%), Gaps = 22/173 (12%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMP-------TTPTVESTEVIFTGIYT 178
P N + V +++ F +FI T I+ N I M T + + + FT +Y
Sbjct: 1086 PKNKCQAVVYDLVMSNQFEIFITTIIITNMIFMAFEHYNQSEVVTEVLATANIAFTILYA 1145
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID--LGN--------LAALR 228
E+ +K++ G + YLR+ WN DF+V+ L+ + ++ G+ L R
Sbjct: 1146 VEAIIKII--GLRIH---YLRNLWNVFDFLVVTLSVMDAFLNDIFGDGIFMNPSLLRVAR 1200
Query: 229 TFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
FR+ R ++ + G++ ++ A++ S+ L ++ L M + ++ ++G+ +
Sbjct: 1201 MFRIGRIIRLIKWAKGMRKLLFALVISLPALFNIGALLMLVMFIYTIIGMSSF 1253
Score = 42.3 bits (95), Expect = 0.13
Identities = 44/192 (22%), Positives = 86/192 (44%), Gaps = 25/192 (13%)
Query: 777 CCWLWLEFQKYVALLVFDPFVELFITLC----IVVNTLFMALDHHNMDK-DMDKALKSGN 831
C +LE + L F + F T+ +++ + +A M++ ++L++
Sbjct: 824 CLLFFLEMVLKLVALGFVHYYTHFWTILDFTIVIITVISLAASGLGMEQITAFRSLRTLR 883
Query: 832 YLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVD- 890
LR + W + ++++ + ++ ++ N+ V + IFA+MG+QLF + V+
Sbjct: 884 ALRPLRAVSRWQGMKIIVNALMLSIPSIFNVLLVCVVFWLIFAIMGVQLFAGKFYKCVNE 943
Query: 891 ---RFPDGDLPR----------W-----NFTDFMHSFMIVFRVLCGE-WIESMWDCMLVG 931
R P ++ W NF + +F+ +F+V E W+E M D + V
Sbjct: 944 TNMRIPPTEVANKIECYNKNYTWVNSNVNFDNVGGAFLALFQVATFEGWMEIMADAVDVT 1003
Query: 932 DVSCIPFFLATV 943
+V P F ATV
Sbjct: 1004 EVDEQPKFEATV 1015
Score = 39.5 bits (88), Expect = 0.91
Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 5/92 (5%)
Query: 785 QKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPT 844
Q V LV E+FIT I+ N +FMA +H+N + + + L + N A
Sbjct: 1091 QAVVYDLVMSNQFEIFITTIIITNMIFMAFEHYNQSEVVTEVLATANIAFTILYA----- 1145
Query: 845 LNLLISIMGRTMGALGNLTFVLCIIIFIFAVM 876
+ +I I+G + L NL V ++ +VM
Sbjct: 1146 VEAIIKIIGLRIHYLRNLWNVFDFLVVTLSVM 1177
Score = 36.3 bits (80), Expect = 8.5
Identities = 27/118 (22%), Positives = 56/118 (47%), Gaps = 9/118 (7%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKN 884
+ + G +R+ K AK L + I ++ AL N+ +L +++FI+ ++GM FG+
Sbjct: 1200 RMFRIGRIIRLIKWAKGMRKLLFALVI---SLPALFNIGALLMLVMFIYTIIGMSSFGQ- 1255
Query: 885 YVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVSCIPFFLAT 942
+ D + NF F +F+++ R+ + +L+ +C P ++ T
Sbjct: 1256 -IKLSGALND----QVNFQTFGKTFLLLVRLATSAGWNDILGPLLIQPPNCDPNYITT 1308
>UniRef50_A7SKR1 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1534
Score = 676 bits (1671), Expect = 0.0
Identities = 324/672 (48%), Positives = 467/672 (69%), Gaps = 8/672 (1%)
Query: 1197 DSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMD 1256
DS F W +R K +L+E+ FE ++ +I SS++LA EDV+L +P L+ +L ++
Sbjct: 806 DSGFCAVWKVMRYKVRRLVEHKVFEGIILFLIAASSISLAFEDVYLDSKPTLKQVLQILN 865
Query: 1257 RIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMR 1316
+F VIF +EML+KW+ LGF+ YFTN W LDF+IV+VS++ +A + G I +++R
Sbjct: 866 ILFAVIFTVEMLLKWIGLGFKTYFTNPWNILDFVIVIVSIMVSLATIFGNDQIAFIRSLR 925
Query: 1317 TLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKC 1376
TLRA RPLRA+SR +GM+VV+ +L+ AIP I NVLLVCL+FWLIF+IMGVQ+F GK+ KC
Sbjct: 926 TLRAFRPLRAISRFEGMKVVITSLLHAIPGIGNVLLVCLMFWLIFSIMGVQIFGGKFGKC 985
Query: 1377 VDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAI 1436
VD ++P+K C Y WENS +NFD V + +L L QVATF+GW++IM DA+
Sbjct: 986 VDEGGEKCPASVVPNKTVCLSNGYRWENSNINFDTVDQGFLALLQVATFEGWMEIMEDAV 1045
Query: 1437 DSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNE--QKKKAGGSLEMF 1494
D+ ++ QPI E N+ YL+ TLNLFIGVIIDNFN+ Q+ +A GS+++F
Sbjct: 1046 DATKIDEQPIEENNVSAYLFFVVFIILGTFFTLNLFIGVIIDNFNQLKQQMEAVGSMDVF 1105
Query: 1495 MTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMT 1554
+T Q+ + NA+K +KKP K I RP+ + Q ++++V +KF++ IMLFI +NM+ M
Sbjct: 1106 LTSTQRNWMNALKSAATKKPKKRIRRPQNKFQGELYDMVQSRKFEVFIMLFITINMVVMM 1165
Query: 1555 LDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSL 1614
+ HY +S + LN+IF +F E +L+I ALR YF+ PWN+FDFV+V+ SI+ +
Sbjct: 1166 VQHYDHLAVWSKQI--LNLIFTSVFILEAILRIIALRKGYFLNPWNVFDFVIVISSIIGI 1223
Query: 1615 VLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFL 1674
++ ++ ++P+LLRVVRV +VGR+LR + A+GIR LLF+L +S PALFNI LLFL
Sbjct: 1224 IVENLQTSLVINPSLLRVVRVFRVGRLLRFFEAARGIRRLLFSLVISTPALFNIGALLFL 1283
Query: 1675 VMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGI-INEEE 1733
++FI+AI GMS F HVK L+DV NF+TF S +LLF++ TSAGW+ +LD + I+E +
Sbjct: 1284 IIFIYAIIGMSIFGHVKKTEALNDVVNFETFGSSFVLLFRLMTSAGWNDILDPLMISEPD 1343
Query: 1734 CDLPDNERGSP-GNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLT 1792
CD N RG P GNCG+ + YL S++VI FLI+INMYIAVILENY+Q E + G+T
Sbjct: 1344 CD--PNYRGLPSGNCGNKYMAPIYLGSFVVIIFLILINMYIAVILENYNQVMEQEKIGIT 1401
Query: 1793 DDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHKPNKYKIISMDIPICRGDM 1852
++D +++Y++W+ FDP+ +QYI Y LSDF+ +E L+I KPNK ++IP+ +GD
Sbjct: 1402 NEDIELFYQMWELFDPNATQYIPYADLSDFVHQMEGNLRIPKPNKAACALLNIPLVKGDK 1461
Query: 1853 MFCVDILDALTK 1864
+ C+D+L AL K
Sbjct: 1462 IHCLDLLQALVK 1473
Score = 277 bits (678), Expect = 3e-72
Identities = 139/327 (42%), Positives = 207/327 (63%), Gaps = 27/327 (8%)
Query: 100 QTTFVVISK-GK-DIFRFSATNALWILDPFNPIRRVAIYILV--HPLF----SLFIITTI 151
Q+ V+ K GK ++RF+ + +L++ P NPIR+ ++ ++ +PL +F++ TI
Sbjct: 1 QSFLVIAGKFGKTQVYRFNRSKSLYLFGPENPIRQFSLKLITNQYPLQLHNRHMFVLLTI 60
Query: 152 LVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIA 211
LVNC+ + M P E E +F IYT E K++A+GF L + YLRD WNWLDF+V+
Sbjct: 61 LVNCVFLAMTNPP--EQPEYVFAAIYTIEMFCKIIAKGFALHRYAYLRDKWNWLDFIVVI 118
Query: 212 LAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLS 271
L VT+ D+ NL+ + TFRV RAL+T++ V GLK +V ++ S+K L DV++LT+F +
Sbjct: 119 LGNVTISPDVANLSGIPTFRVFRALRTISAVKGLKAMVNTLLVSMKMLWDVMVLTLFFIC 178
Query: 272 VFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSS 331
+FAL+G+Q+++G L KC PE NL+ + + N + WY E + LCGN++
Sbjct: 179 IFALIGMQLFIGELRNKCALPVPE-----NLS-VPYRTYASNSSIWYLEDNEPILCGNTT 232
Query: 332 GAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ---------- 381
G+ C Y CL G NPN+GYTSFD FGWA L+ F+L+T D+WEN+Y
Sbjct: 233 GSRTCPTNYTCLPHAGGNPNFGYTSFDHFGWALLTGFQLITLDFWENVYNNVIYTMGPWY 292
Query: 382 -LFFVVIIFLGSFYLVNLILAIVAMSY 407
++F V+IF G F+LVNL+LA+VA SY
Sbjct: 293 VVYFAVVIFFGPFFLVNLVLAVVAASY 319
Score = 147 bits (356), Expect = 3e-33
Identities = 68/119 (57%), Positives = 90/119 (75%), Gaps = 4/119 (3%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L++ LRV KLAKSW T+N L++ +G+++GALGNLT +L II++IFAVMGMQL G +Y
Sbjct: 599 LRTFRLLRVLKLAKSWSTMNSLLATIGKSLGALGNLTVILAIIVYIFAVMGMQLLGNSYT 658
Query: 887 DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCML-VGDVSCIPFFLATVV 944
D+F G +PRWNF DF HSFM++FRVLCGEWIE +WDCML G V+ + F A ++
Sbjct: 659 P--DKF-GGSIPRWNFKDFPHSFMMIFRVLCGEWIEPLWDCMLATGPVAMLLFVPAFIL 714
Score = 102 bits (245), Expect = 9e-20
Identities = 69/243 (28%), Positives = 125/243 (51%), Gaps = 10/243 (4%)
Query: 1478 DNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRW-RPQAIVFEIVTDK 1536
D QK + ++ + K N K KK + R RW R + + + K
Sbjct: 447 DIIGSQKSNLNNASQIISSH--KSSLNLSVKKEEKKRSSIMAR-RWKRFRRRLLKFTNGK 503
Query: 1537 KFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFV 1596
++ I++ I LN L M+++H + + V++ N +F IF E +LK+ AL + ++
Sbjct: 504 VMEIFIIVCILLNTLVMSIEHPRLEDPLLTVVNISNEVFTFIFLLEMILKLIALGFLGYI 563
Query: 1597 E-PWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLL 1655
WN+FD +VV+ SI+ +++ + T + V+R ++ RVL+L K + +LL
Sbjct: 564 RVAWNIFDGIVVIISIVDFIVNKFVPD--AGGTGISVLRTFRLLRVLKLAKSWSTMNSLL 621
Query: 1656 FALAMSLPALFNICLLLFLVMFIFAIFGMSFF--MHVKDK-GGLDDVYNFKTFVQSMILL 1712
+ SL AL N+ ++L ++++IFA+ GM + DK GG +NFK F S +++
Sbjct: 622 ATIGKSLGALGNLTVILAIIVYIFAVMGMQLLGNSYTPDKFGGSIPRWNFKDFPHSFMMI 681
Query: 1713 FQM 1715
F++
Sbjct: 682 FRV 684
Score = 91.9 bits (218), Expect = 2e-16
Identities = 53/174 (30%), Positives = 92/174 (52%), Gaps = 9/174 (5%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W R + K E +I ILL++L +++E L P+L ++ + +FT IF
Sbjct: 489 WKRFRRRLLKFTNGKVMEIFIIVCILLNTLVMSIEHPRLED-PLLT-VVNISNEVFTFIF 546
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAAL----CGAGGIQAFKTMRTLR 1319
+EM++K +ALGF Y AW D I+V++S+++F+ G GI +T R LR
Sbjct: 547 LLEMILKLIALGFLGYIRVAWNIFDGIVVIISIVDFIVNKFVPDAGGTGISVLRTFRLLR 606
Query: 1320 ALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
L+ ++ S M + + + A+ ++ V+L +++ IFA+MG+QL Y
Sbjct: 607 VLKLAKSWSTMNSLLATIGKSLGALGNL-TVILAIIVY--IFAVMGMQLLGNSY 657
Score = 76.6 bits (180), Expect = 7e-12
Identities = 38/120 (31%), Positives = 68/120 (56%), Gaps = 6/120 (5%)
Query: 1253 YYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAF 1312
Y I+T+ F +++ K AL Y + W WLDFI+V++ + + GI F
Sbjct: 78 YVFAAIYTIEMFCKIIAKGFALHRYAYLRDKWNWLDFIVVILGNVTISPDVANLSGIPTF 137
Query: 1313 KTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGK 1372
R R LR +S ++G++ +VN L+ ++ +++V+++ L F IFA++G+QLF G+
Sbjct: 138 ------RVFRALRTISAVKGLKAMVNTLLVSMKMLWDVMVLTLFFICIFALIGMQLFIGE 191
Score = 68.1 bits (159), Expect = 2e-09
Identities = 62/252 (24%), Positives = 119/252 (47%), Gaps = 30/252 (11%)
Query: 161 PTTPTV-ESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALA-YVTMG 218
PT V + ++F I+T E +K + GF TY + WN LDFV++ ++ V++
Sbjct: 855 PTLKQVLQILNILFAVIFTVEMLLKWIGLGFK----TYFTNPWNILDFVIVIVSIMVSLA 910
Query: 219 IDLGN-----LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVF 273
GN + +LRT R R L+ ++ G+K ++ +++ ++ + +V+++ + +F
Sbjct: 911 TIFGNDQIAFIRSLRTLRAFRPLRAISRFEGMKVVITSLLHAIPGIGNVLLVCLMFWLIF 970
Query: 274 ALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGA 333
++MG+QI+ G KCV ++G ++ N+T G Y ++
Sbjct: 971 SIMGVQIFGGKF-GKCV----DEGG-----EKCPASVVPNKTVCLSNG--YRWENSNINF 1018
Query: 334 GQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ--LFFVVIIFLG 391
+ G++ L + D + A ++ Q EN LFFVV I LG
Sbjct: 1019 DTVDQGFLALLQVATFEGWMEIMEDA-----VDATKIDEQPIEENNVSAYLFFVVFIILG 1073
Query: 392 SFYLVNLILAIV 403
+F+ +NL + ++
Sbjct: 1074 TFFTLNLFIGVI 1085
Score = 64.1 bits (149), Expect = 4e-08
Identities = 43/153 (28%), Positives = 81/153 (52%), Gaps = 18/153 (11%)
Query: 142 LFSLFIITTILVNCILMIM-------PTTPTVESTEVIFTGIYTFESAVKVMARGFILQP 194
+ +FII IL+N ++M + P V + +FT I+ E +K++A GF+
Sbjct: 504 VMEIFIIVCILLNTLVMSIEHPRLEDPLLTVVNISNEVFTFIFLLEMILKLIALGFL--- 560
Query: 195 FTYLRDAWNWLDFVVIALAYVTMGI-----DLGN--LAALRTFRVLRALKTVAIVPGLKT 247
Y+R AWN D +V+ ++ V + D G ++ LRTFR+LR LK + +
Sbjct: 561 -GYIRVAWNIFDGIVVIISIVDFIVNKFVPDAGGTGISVLRTFRLLRVLKLAKSWSTMNS 619
Query: 248 IVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
++ + +S+ L ++ ++ + +FA+MG+Q+
Sbjct: 620 LLATIGKSLGALGNLTVILAIIVYIFAVMGMQL 652
Score = 54.8 bits (126), Expect = 2e-05
Identities = 36/120 (30%), Positives = 61/120 (50%), Gaps = 14/120 (11%)
Query: 1574 IFIVIFSSECLLKI----FAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPT 1628
+F I++ E KI FAL RY Y + WN DF+VV+ ++ +S + PT
Sbjct: 79 VFAAIYTIEMFCKIIAKGFALHRYAYLRDKWNWLDFIVVILG--NVTISPDVANLSGIPT 136
Query: 1629 LLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
+V R LR + KG++ ++ L +S+ L+++ +L + IFA+ GM F+
Sbjct: 137 F-------RVFRALRTISAVKGLKAMVNTLLVSMKMLWDVMVLTLFFICIFALIGMQLFI 189
Score = 50.0 bits (114), Expect = 6e-04
Identities = 41/146 (28%), Positives = 73/146 (50%), Gaps = 9/146 (6%)
Query: 792 VFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISI 851
VFD + + + I+V L +L + + + + G LR F+ A+ LL S+
Sbjct: 1210 VFDFVIVISSIIGIIVENLQTSLVINPSLLRVVRVFRVGRLLRFFEAARG--IRRLLFSL 1267
Query: 852 MGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMI 911
+ T AL N+ +L +IIFI+A++GM +FG +V + D NF F SF++
Sbjct: 1268 VISTP-ALFNIGALLFLIIFIYAIIGMSIFG--HVKKTEALND----VVNFETFGSSFVL 1320
Query: 912 VFRVLCGEWIESMWDCMLVGDVSCIP 937
+FR++ + D +++ + C P
Sbjct: 1321 LFRLMTSAGWNDILDPLMISEPDCDP 1346
Score = 46.8 bits (106), Expect = 0.006
Identities = 36/155 (23%), Positives = 79/155 (50%), Gaps = 23/155 (14%)
Query: 143 FSLFIITTILVNCILMIMPTTP--TVESTEV---IFTGIYTFESAVKVMA--RGFILQPF 195
F +FI+ I +N ++M++ V S ++ IFT ++ E+ ++++A +G+ L P
Sbjct: 1149 FEVFIMLFITINMVVMMVQHYDHLAVWSKQILNLIFTSVFILEAILRIIALRKGYFLNP- 1207
Query: 196 TYLRDAWNWLDFVVIALAYV---------TMGIDLGNLAALRTFRVLRALKTVAIVPGLK 246
WN DFV++ + + ++ I+ L +R FRV R L+ G++
Sbjct: 1208 ------WNVFDFVIVISSIIGIIVENLQTSLVINPSLLRVVRVFRVGRLLRFFEAARGIR 1261
Query: 247 TIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
++ +++ S L ++ L + ++A++G+ I+
Sbjct: 1262 RLLFSLVISTPALFNIGALLFLIIFIYAIIGMSIF 1296
Score = 36.3 bits (80), Expect = 8.5
Identities = 25/112 (22%), Positives = 52/112 (46%), Gaps = 4/112 (3%)
Query: 779 WLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKL 838
W+ L F+ Y +P+ L + IV + +A N ++L++ R +
Sbjct: 880 WIGLGFKTYFT----NPWNILDFVIVIVSIMVSLATIFGNDQIAFIRSLRTLRAFRPLRA 935
Query: 839 AKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVD 890
+ + ++I+ + + +GN+ V + IF++MG+Q+FG + VD
Sbjct: 936 ISRFEGMKVVITSLLHAIPGIGNVLLVCLMFWLIFSIMGVQIFGGKFGKCVD 987
>UniRef50_O44930 Cluster: Putative voltage-gated sodium channel; n=1;
Aiptasia pallida|Rep: Putative voltage-gated sodium
channel - Aiptasia pallida (Sea anemone)
Length = 1810
Score = 653 bits (1613), Expect = 0.0
Identities = 323/692 (46%), Positives = 454/692 (65%), Gaps = 9/692 (1%)
Query: 1179 DCCPEQCYQKFPF--LAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALA 1236
+CCP C K + S ++ W LRL K +E+ YFE ++ +I+ SS+AL
Sbjct: 1007 ECCP-WCMNKMTCGCITRWKASDGYRSWRNLRLAVKKFVEHKYFEWTILAIIMASSIALT 1065
Query: 1237 LEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSL 1296
ED++LP RP L++ L Y++ F V F IE L+K L LG YF N W LD +IV V +
Sbjct: 1066 FEDINLPSRPKLKEYLQYLNIFFAVTFSIEFLLKVLGLGVVSYFRNCWNCLDVLIVFVPV 1125
Query: 1297 INFVAALCGA-GGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCL 1355
+ +A + + +++RTLRALRPLRA+SR +GMRVVVN+L+ AIP I NVLLVC+
Sbjct: 1126 SSVIADSSNQDSSLSSLRSLRTLRALRPLRAISRWEGMRVVVNSLLFAIPGIGNVLLVCM 1185
Query: 1356 IFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKA 1415
+FWLIF+IMGVQ F G++FKCVD N L I+ +++ C + Y W NS +NFD+
Sbjct: 1186 VFWLIFSIMGVQFFGGRFFKCVDNNKERLPISIVQNRSECIQKGYRWVNSDINFDNSLNG 1245
Query: 1416 YLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGV 1475
++ LFQVATF+GWI++M DA+D+REV +QP N Y Y TLNLFIGV
Sbjct: 1246 FMALFQVATFEGWIEVMRDAVDAREVDQQPSDGYNFSAYAYFVVFIIVGSFFTLNLFIGV 1305
Query: 1476 IIDNFNEQKKKAG--GSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIV 1533
IIDNFN KK+ G+L++ +T Q+ ++ ++K +KKP K I RP A +F+++
Sbjct: 1306 IIDNFNRLKKQYEDFGALDVLLTPSQRAWFGTIRKAATKKPKKVISRPENSFMAWLFDVI 1365
Query: 1534 TDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH 1593
+F+ +IM FI LN+L M + HY Q L +N++F +F+ E +L+I LR H
Sbjct: 1366 HSSRFETLIMFFICLNILVMMIQHYGQKPAVEQALMIINLVFTGLFTLEAILRIVVLRLH 1425
Query: 1594 YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRT 1653
YF EPWN+FDFV+V+ SIL ++L + + F++P+ V RV ++GR+LR KGAKGIR
Sbjct: 1426 YFREPWNVFDFVIVVLSILGIILEHLEYELFITPSPF-VARVFRIGRLLRFYKGAKGIRR 1484
Query: 1654 LLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLF 1713
LLFAL +SLPAL NI LLFL+MFI+AI GMS F +VK G LD V NF+TF SM+LLF
Sbjct: 1485 LLFALIISLPALLNIGALLFLIMFIYAIIGMSSFGYVKKTGALDSVVNFETFGNSMLLLF 1544
Query: 1714 QMSTSAGWDGVLDG-IINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMY 1772
++STSAGW+ VL +I +CD GNC + + + Y ++++ +FLI+INMY
Sbjct: 1545 RLSTSAGWNDVLKPLLIKPPDCD-KKLWCIPNGNCSTPWLAVVYFTTFILFTFLIIINMY 1603
Query: 1773 IAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQI 1832
IA+ILEN SQA E + G+TDDD DM+Y W+RFDP +QYI + LSDF+D L+ PL+I
Sbjct: 1604 IAIILENLSQAHEQEEVGVTDDDLDMFYYHWERFDPGATQYIPHSALSDFVDGLDHPLRI 1663
Query: 1833 HKPNKYKIISMDIPICRGDMMFCVDILDALTK 1864
+PNK+ I+++IPI +GD + C D++ AL +
Sbjct: 1664 PQPNKFACINLNIPIKQGDRVHCFDVMQALVR 1695
Score = 311 bits (763), Expect = 1e-82
Identities = 156/341 (45%), Positives = 221/341 (64%), Gaps = 24/341 (7%)
Query: 82 PLELASTPLEDIDPFYHNQTTFVVISK-GKD-IFRFSATNALWILDPFNPIRRVAIYILV 139
P E PLED D N+T VV S+ GK ++RF+ +L++ P +PIR+ I +
Sbjct: 53 PDEFLHQPLEDFDSG-SNKTFVVVASRFGKQYVYRFNKAKSLYLFGPLHPIRKAVILFIT 111
Query: 140 HPLFSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLR 199
+ F FI+ TI+VNCI + + P E E +F IYTFE +K++A+G ++ + YLR
Sbjct: 112 NQFFEFFILLTIIVNCIFLALRDAP--EQPEYVFAAIYTFEMLLKIIAKGLVMHEYAYLR 169
Query: 200 DAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNL 259
D WNWLDFVV+ L YVT+ ++ NL+ +R FRVLRAL+T++ V GLKT+V A+++S+K L
Sbjct: 170 DPWNWLDFVVVILGYVTLVPNVANLSGIRIFRVLRALRTISAVEGLKTMVNALLKSMKML 229
Query: 260 RDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYG 319
DV+ILT F L VFAL+G+Q+++G L KCV P + T +++ F NE++WY
Sbjct: 230 SDVLILTTFFLCVFALVGMQLFVGSLRNKCVLKPPLN------TTIDYDSFVTNESHWYH 283
Query: 320 E-GGDYPL-CGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWE 377
D P+ CGNS+ AG C Y CL G NPNYGYT+ D FGWA ++AF+L+T DYWE
Sbjct: 284 HPDTDTPITCGNSTSAGPCPLNYTCLANIGNNPNYGYTNLDNFGWAVITAFQLVTLDYWE 343
Query: 378 NLYQ-----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
N+Y +F ++IF GSFYL+NL+LA+VA+SY
Sbjct: 344 NVYNYVLSSMGSWYIFYFFMVIFFGSFYLLNLVLAVVAVSY 384
Score = 144 bits (349), Expect = 2e-32
Identities = 73/154 (47%), Positives = 104/154 (67%), Gaps = 9/154 (5%)
Query: 792 VFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISI 851
+FD F+ + + ++V L +D H+ + L++ LRVFKLA+SW T+N+L+S
Sbjct: 689 IFDGFIVVISMVDLMVELL---VDDHDSGLSV---LRTFRLLRVFKLAQSWQTMNMLLST 742
Query: 852 MGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMI 911
+ R++G LGNLT VL I+I++ AV+G+QLF + Y F +GD+PRWNFTDF HSFM+
Sbjct: 743 IARSVGQLGNLTLVLGIVIYMLAVVGVQLFDQYYT--TKNF-NGDVPRWNFTDFWHSFMM 799
Query: 912 VFRVLCGEWIESMWDCMLVGDVSCIPFFLATVVI 945
+FRVLCGEWIE ++DCM FFL T+VI
Sbjct: 800 IFRVLCGEWIEPLYDCMRASTSWATLFFLTTLVI 833
Score = 91.5 bits (217), Expect = 2e-16
Identities = 52/172 (30%), Positives = 93/172 (54%), Gaps = 14/172 (8%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+R I N +FE ++ I+++ + LAL D P +P Y I+T ++
Sbjct: 102 IRKAVILFITNQFFEFFILLTIIVNCIFLALRDA--PEQPE-----YVFAAIYTFEMLLK 154
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
++ K L + Y + W WLDF++V++ + V + GI+ F R LR LR
Sbjct: 155 IIAKGLVMHEYAYLRDPWNWLDFVVVILGYVTLVPNVANLSGIRIF------RVLRALRT 208
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKCV 1377
+S ++G++ +VNAL++++ + +VL++ F +FA++G+QLF G KCV
Sbjct: 209 ISAVEGLKTMVNALLKSMKMLSDVLILTTFFLCVFALVGMQLFVGSLRNKCV 260
Score = 84.6 bits (200), Expect = 2e-14
Identities = 45/177 (25%), Positives = 95/177 (53%), Gaps = 3/177 (1%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W +R K++ + Y +T + ++++L L+LE ++ ++ +L +++FT++F
Sbjct: 609 WNRIRRMISKIVLHGYMDTFITFCTMVNTLFLSLEYHNMDSNYLM--VLEIGNKVFTMVF 666
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRP 1323
+EM++K A GF+ Y + W D IV++S+++ + L +RT R LR
Sbjct: 667 LLEMILKITAFGFKGYIKSRWNIFDGFIVVISMVDLMVELLVDDHDSGLSVLRTFRLLRV 726
Query: 1324 LRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMN 1380
+ Q M ++++ + +++ + N+ LV I + A++GVQLF +Y+ + N
Sbjct: 727 FKLAQSWQTMNMLLSTIARSVGQLGNLTLVLGIVIYMLAVVGVQLF-DQYYTTKNFN 782
Score = 83.4 bits (197), Expect = 6e-14
Identities = 70/266 (26%), Positives = 138/266 (51%), Gaps = 26/266 (9%)
Query: 1522 RW-RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFS 1580
+W R + ++ +IV D I +N L ++L+++ + VL+ N +F ++F
Sbjct: 608 KWNRIRRMISKIVLHGYMDTFITFCTMVNTLFLSLEYHNMDSNYLMVLEIGNKVFTMVFL 667
Query: 1581 SECLLKIFALRYHYFVEP-WNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVG 1639
E +LKI A + +++ WN+FD +V+ S++ L++ +++ + ++LR R+
Sbjct: 668 LEMILKITAFGFKGYIKSRWNIFDGFIVVISMVDLMVELLVDDHDSGLSVLRTFRLL--- 724
Query: 1640 RVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF-MHVKDKGGLDD 1698
RV +L + + + LL +A S+ L N+ L+L +V+++ A+ G+ F + K D
Sbjct: 725 RVFKLAQSWQTMNMLLSTIARSVGQLGNLTLVLGIVIYMLAVVGVQLFDQYYTTKNFNGD 784
Query: 1699 V--YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITY 1756
V +NF F S +++F+ VL G E L D R S AT+ +
Sbjct: 785 VPRWNFTDFWHSFMMIFR---------VLCGEWIE---PLYDCMRAS---TSWATL---F 826
Query: 1757 LLSYLVISFLIVINMYIAVILENYSQ 1782
L+ LVI +V+N+++A++L +++
Sbjct: 827 FLTTLVIGNFLVLNLFLALLLNAFAR 852
Score = 65.3 bits (152), Expect = 2e-08
Identities = 69/263 (26%), Positives = 114/263 (43%), Gaps = 33/263 (12%)
Query: 1435 AIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKA--GGSLE 1492
++ SR ++P ETN T N I D F Q + GS +
Sbjct: 14 SLTSRSPPQEPYNETN---NANNTLSKSTSTTSTTNSSYVPIPDEFLHQPLEDFDSGSNK 70
Query: 1493 MFMTEDQKKYYNAMKKMGSKKPLKAI-PRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNML 1551
F+ + + + K L P R I+F +T++ F+ I+L I +N +
Sbjct: 71 TFVVVASRFGKQYVYRFNKAKSLYLFGPLHPIRKAVILF--ITNQFFEFFILLTIIVNCI 128
Query: 1552 TMTL-DHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL-----RYHYFVEPWNLFDFV 1605
+ L D +Q E +F I++ E LLKI A Y Y +PWN DFV
Sbjct: 129 FLALRDAPEQPE----------YVFAAIYTFEMLLKIIAKGLVMHEYAYLRDPWNWLDFV 178
Query: 1606 VVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPAL 1665
VV+ ++LV + L +R+ +V R LR + +G++T++ AL S+ L
Sbjct: 179 VVILGYVTLV---------PNVANLSGIRIFRVLRALRTISAVEGLKTMVNALLKSMKML 229
Query: 1666 FNICLLLFLVMFIFAIFGMSFFM 1688
++ +L + +FA+ GM F+
Sbjct: 230 SDVLILTTFFLCVFALVGMQLFV 252
Score = 60.5 bits (140), Expect = 5e-07
Identities = 43/176 (24%), Positives = 90/176 (51%), Gaps = 22/176 (12%)
Query: 132 RVAIYILV-HPLFSLFIITTILVNCILMI-----MPTTPTVES----TEVIFTGIYTFES 181
R+A+ V H F I+ I+ + I + +P+ P ++ + F ++ E
Sbjct: 1037 RLAVKKFVEHKYFEWTILAIIMASSIALTFEDINLPSRPKLKEYLQYLNIFFAVTFSIEF 1096
Query: 182 AVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID-------LGNLAALRTFRVLR 234
+KV+ G + +Y R+ WN LD +++ + ++ D L +L +LRT R LR
Sbjct: 1097 LLKVLGLGVV----SYFRNCWNCLDVLIVFVPVSSVIADSSNQDSSLSSLRSLRTLRALR 1152
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCV 290
L+ ++ G++ +V +++ ++ + +V+++ M +F++MG+Q + G KCV
Sbjct: 1153 PLRAISRWEGMRVVVNSLLFAIPGIGNVLLVCMVFWLIFSIMGVQFFGGRFF-KCV 1207
Score = 57.2 bits (132), Expect = 4e-06
Identities = 48/197 (24%), Positives = 88/197 (44%), Gaps = 21/197 (10%)
Query: 127 FNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT-------TPTVESTEVIFTGIYTF 179
+N IRR+ I++H FI +VN + + + +E +FT ++
Sbjct: 609 WNRIRRMISKIVLHGYMDTFITFCTMVNTLFLSLEYHNMDSNYLMVLEIGNKVFTMVFLL 668
Query: 180 ESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDL------GNLAALRTFRVL 233
E +K+ A GF Y++ WN D ++ ++ V + ++L L+ LRTFR+L
Sbjct: 669 EMILKITAFGFK----GYIKSRWNIFDGFIVVISMVDLMVELLVDDHDSGLSVLRTFRLL 724
Query: 234 RALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVF 293
R K + ++ + SV L ++ ++ + + A++G+Q++ T K F
Sbjct: 725 RVFKLAQSWQTMNMLLSTIARSVGQLGNLTLVLGIVIYMLAVVGVQLFDQYYT---TKNF 781
Query: 294 PEDGSWGNLTDENWERF 310
D N TD W F
Sbjct: 782 NGDVPRWNFTD-FWHSF 797
Score = 50.4 bits (115), Expect = 5e-04
Identities = 19/51 (37%), Positives = 34/51 (66%)
Query: 781 WLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGN 831
W ++ ++ +V +++ FIT C +VNTLF++L++HNMD + L+ GN
Sbjct: 609 WNRIRRMISKIVLHGYMDTFITFCTMVNTLFLSLEYHNMDSNYLMVLEIGN 659
Score = 48.0 bits (109), Expect = 0.003
Identities = 39/156 (25%), Positives = 79/156 (50%), Gaps = 24/156 (15%)
Query: 143 FSLFIITTILVNCILMIMP---TTPTVEST----EVIFTGIYTFESAVKVMARGFILQPF 195
F I+ I +N ++M++ P VE ++FTG++T E+ ++++ +L+
Sbjct: 1370 FETLIMFFICLNILVMMIQHYGQKPAVEQALMIINLVFTGLFTLEAILRIV----VLR-L 1424
Query: 196 TYLRDAWNWLDFVVIALAYVTMGIDLGNLA----------ALRTFRVLRALKTVAIVPGL 245
Y R+ WN DFV++ L+ +GI L +L R FR+ R L+ G+
Sbjct: 1425 HYFREPWNVFDFVIVVLS--ILGIILEHLEYELFITPSPFVARVFRIGRLLRFYKGAKGI 1482
Query: 246 KTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+ ++ A+I S+ L ++ L + ++A++G+ +
Sbjct: 1483 RRLLFALIISLPALLNIGALLFLIMFIYAIIGMSSF 1518
Score = 44.4 bits (100), Expect = 0.032
Identities = 39/157 (24%), Positives = 69/157 (43%), Gaps = 22/157 (14%)
Query: 803 LCIVVNTLFMALDHHNMDKDMD--KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALG 860
L + V + D N D + ++L++ LR + W + ++++ + + +G
Sbjct: 1119 LIVFVPVSSVIADSSNQDSSLSSLRSLRTLRALRPLRAISRWEGMRVVVNSLLFAIPGIG 1178
Query: 861 NLTFVLCIIIFIFAVMGMQLFGKNYVDYVD----RFPDGDLP----------RW-----N 901
N+ V + IF++MG+Q FG + VD R P + RW N
Sbjct: 1179 NVLLVCMVFWLIFSIMGVQFFGGRFFKCVDNNKERLPISIVQNRSECIQKGYRWVNSDIN 1238
Query: 902 FTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSCIP 937
F + ++ FM +F+V E WIE M D + +V P
Sbjct: 1239 FDNSLNGFMALFQVATFEGWIEVMRDAVDAREVDQQP 1275
>UniRef50_Q9NKV1 Cluster: Sodium channel; n=3; Chordata|Rep: Sodium
channel - Halocynthia roretzi (Sea squirt)
Length = 2221
Score = 634 bits (1567), Expect = e-180
Identities = 303/703 (43%), Positives = 466/703 (66%), Gaps = 16/703 (2%)
Query: 1164 IKVGADEDVVDDTPADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETA 1223
I+ G D + + P + P+ C K+ L+G+ + W R F L+++ FE
Sbjct: 1129 IQGGKDSGMENQQPKEA-PD-CLPKWCPLSGETFCCA-KTWAKFRYGVFLLVQHRIFEFF 1185
Query: 1224 VITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNA 1283
++ +IL S++ LA+ED+HL +++L ++ +FT +F +EM++KW+ GF KYFTN
Sbjct: 1186 ILAIILASTVCLAMEDIHLETDITRKNVLNILEYVFTSLFTLEMVLKWIGNGFTKYFTNW 1245
Query: 1284 WCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQA 1343
WC LDF+IV++S + A+ AG + + + +RTLRALRPLRA+SR QGMRVVVNAL+
Sbjct: 1246 WCVLDFVIVVISWVGIGAS--AAGTVDSLRALRTLRALRPLRAISRWQGMRVVVNALIYC 1303
Query: 1344 IPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWE 1403
IPSI NVL VCL+ WL+F IMGVQL+ G++++CVD + T + +P++ C N+TW
Sbjct: 1304 IPSIGNVLCVCLLIWLVFRIMGVQLYKGQFYRCVDSSGTAYNATFVPNRTICLQNNFTWT 1363
Query: 1404 NSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXX 1463
P+NFD+V + LFQVATF+GWI++M+DA D+ V QP R N Y Y++
Sbjct: 1364 TPPINFDNVVNGMIALFQVATFEGWIEVMSDASDTDGVYNQPTRGANPYSYVFFFIFVLI 1423
Query: 1464 XXXXTLNLFIGVIIDNFNEQKK--KAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRP 1521
LNL +GVII++F + +K + ++E F+TE QK +Y M+ M ++KP K+IP P
Sbjct: 1424 GSFFILNLIVGVIIESFQKLRKQTETSSAVEAFLTESQKNFYKTMRTMLNRKPKKSIPPP 1483
Query: 1522 RWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSS 1581
R +F++VT KF++++ + I LNMLT+ ++HY+ S+ ++ L Y+++ F +F+
Sbjct: 1484 RNALLLKIFKLVTHSKFEVVVFVVIVLNMLTLGMEHYRMSQNWADALRYVDIGFTSLFAV 1543
Query: 1582 ECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRV 1641
E LK+ R +YF + +N+FDFVVV+ SI +L +++ VSPTLLRVVRV +V RV
Sbjct: 1544 EAFLKLCGTRLYYFRDAFNVFDFVVVLLSITGFILEELL-TLLVSPTLLRVVRVFRVFRV 1602
Query: 1642 LRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYN 1701
LR+++ A+GIR L+ L +SLP LFNI ++L + M IFAI GMSFFM+VK +G L+D+ N
Sbjct: 1603 LRVIRAARGIRRLILTLMISLPPLFNIAVILGVFMVIFAILGMSFFMNVKLRGALNDIVN 1662
Query: 1702 FKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYL 1761
F+TF SM+LLF++ TSAGW+ VL+ ++NEE+C+ P CG+ I + Y + Y+
Sbjct: 1663 FRTFGNSMMLLFRLMTSAGWNDVLEPLMNEEDCE--------PKECGNRIIAVIYFVLYI 1714
Query: 1762 VISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSD 1821
FL+++NMYIA+ILEN+ + + + G++ DD++ +Y IW R+DP SQ++ +LS+
Sbjct: 1715 FFVFLVIVNMYIAIILENFDEIFQQEETGVSQDDFEYFYVIWGRYDPKASQFVSAAELSN 1774
Query: 1822 FLDVLEPPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTK 1864
L L PP Q+ KPN+ KI ++++PI GD + C+D+L AL K
Sbjct: 1775 LLHSLHPPFQLAKPNEIKIAALNLPIVNGDKVHCLDVLFALVK 1817
Score = 324 bits (795), Expect = 2e-86
Identities = 175/428 (40%), Positives = 251/428 (58%), Gaps = 31/428 (7%)
Query: 4 DLDSISEEERSLFRPFTRESLXXXXXXXXXXXXKQKELEKKRAEGEVRYXXXXXXXGPQP 63
+++ I EE S + T L K+K+ K +AE P
Sbjct: 21 EMNPIEEELESDYTALTSGYLQGLKTKRKQLKEKKKKA-KTKAENSKEKSAENDNHDEYP 79
Query: 64 DATLEQGLPLPVRMQGSFPLELASTPLEDIDPFYHN--QTTFVVIS---KGKDIFRFSAT 118
D TL LP + G FP L P+ED+D +Y + TF V++ K I+RFSA+
Sbjct: 80 DPTLADSEVLP-QYYGKFPDNLLGVPIEDLDSYYKEKGEETFCVVTDRFSNKYIYRFSAS 138
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYT 178
N ++L PFNP+RR+A+ I ++ F F++ TI+VNC + + +ES E +FT IY+
Sbjct: 139 NGFFLLSPFNPLRRLALRITINQFFDYFVMLTIIVNCAFLALDDE-IIES-EYVFTAIYS 196
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM--------GIDLGNLAALRTF 230
E +K++ARGF+L FTYLRD WNWLDFVV+ LAYVT+ G + N++ LRTF
Sbjct: 197 LEMIIKMLARGFVLNKFTYLRDLWNWLDFVVVVLAYVTIISTSVTPAGSNF-NVSGLRTF 255
Query: 231 RVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCV 290
RVLRA K+ IVPGLKTIV A+++S+K L +V+++ +F + V +L+ LQ Y GVL +KCV
Sbjct: 256 RVLRAFKSFTIVPGLKTIVNALLQSLKPLAEVMVIMIFLVVVISLIALQAYQGVLLRKCV 315
Query: 291 KVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNP 350
V T++ + F N NW G+ +CGN+S +G C GY C+Q G NP
Sbjct: 316 LV--PTAKDNITTNDQFNAFVTNPGNWNPVDGELLVCGNTSSSGLCPAGYKCMQDIGENP 373
Query: 351 NYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLI 399
N+G+T+FD GWA L+ F+L+T DYWEN+Y LFF + + LG FYL+NL+
Sbjct: 374 NFGFTNFDHMGWALLTCFQLLTLDYWENVYNMIIRAEGAWNVLFFFMSVVLGPFYLLNLL 433
Query: 400 LAIVAMSY 407
LA+V ++Y
Sbjct: 434 LAVVTLAY 441
Score = 134 bits (324), Expect = 2e-29
Identities = 62/163 (38%), Positives = 101/163 (61%), Gaps = 4/163 (2%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L++ +RVF+LA+ W T+ L+SI+ +++ A+ LT VL +++FIFAV+G Q++ + Y+
Sbjct: 733 LRTLRLMRVFRLARIWQTMRKLMSIIIKSLSAVAYLTVVLFMVLFIFAVIGKQMYSEYYI 792
Query: 887 DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVSCIPFFLATVVIX 946
+ D+F DG++PRWNF +F +SF++V+RV+CGEWIE + +CM + D +CIP FLA +
Sbjct: 793 NSADKF-DGEIPRWNFINFYNSFLLVWRVMCGEWIELLHECMFIADYTCIPVFLAITFLG 851
Query: 947 XXXXXXXXXXXXXXXXXXXXXXTPTADQDTNKI---AEAFNRI 986
T AD+ T K+ EAF ++
Sbjct: 852 NFLVLNLFTAILLEAFNVDNLKTKQADKQTAKLKLGVEAFRKL 894
Score = 103 bits (247), Expect = 5e-20
Identities = 77/262 (29%), Positives = 139/262 (53%), Gaps = 31/262 (11%)
Query: 1526 QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLL 1585
Q +F +++ K F+ +I+L I N L + LDH++ S+TF L N++F IF++E +L
Sbjct: 632 QKFLFALISLKVFEGLIILSILTNTLFLALDHHEISQTFDEALSIGNLVFTAIFTAEAVL 691
Query: 1586 KIFAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRL 1644
KIFAL Y + WN+FDF++V+ S++ + L V+R ++ RV RL
Sbjct: 692 KIFALGPAGYVKDKWNVFDFLIVIISLIEVT-------NITGDAGLSVLRTLRLMRVFRL 744
Query: 1645 VKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFG----MSFFMHVKDK-GGLDDV 1699
+ + +R L+ + SL A+ + ++LF+V+FIFA+ G ++++ DK G
Sbjct: 745 ARIWQTMRKLMSIIIKSLSAVAYLTVVLFMVLFIFAVIGKQMYSEYYINSADKFDGEIPR 804
Query: 1700 YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLS 1759
+NF F S +L++++ W +L EC + C + IT+L +
Sbjct: 805 WNFINFYNSFLLVWRVMCGE-WIELL------HECMFI-----ADYTCIPVFLAITFLGN 852
Query: 1760 YLVISFLIVINMYIAVILENYS 1781
+L V+N++ A++LE ++
Sbjct: 853 FL------VLNLFTAILLEAFN 868
Score = 82.2 bits (194), Expect = 1e-13
Identities = 48/177 (27%), Positives = 98/177 (55%), Gaps = 17/177 (9%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
LR ++ N +F+ V+ I+++ LAL+D I++ + +FT I+ +E
Sbjct: 150 LRRLALRITINQFFDYFVMLTIIVNCAFLALDD------EIIES-----EYVFTAIYSLE 198
Query: 1267 MLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVA-ALCGAGGIQAFKTMRTLRAL 1321
M+IK LA GF Y + W WLDF++V+++ + ++ ++ AG +RT R L
Sbjct: 199 MIIKMLARGFVLNKFTYLRDLWNWLDFVVVVLAYVTIISTSVTPAGSNFNVSGLRTFRVL 258
Query: 1322 RPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYF-KCV 1377
R ++ + + G++ +VNAL+Q++ + V+++ + ++ +++ +Q + G KCV
Sbjct: 259 RAFKSFTIVPGLKTIVNALLQSLKPLAEVMVIMIFLVVVISLIALQAYQGVLLRKCV 315
Score = 81.0 bits (191), Expect = 3e-13
Identities = 51/167 (30%), Positives = 87/167 (52%), Gaps = 6/167 (3%)
Query: 1212 FKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKW 1271
F LI FE +I IL ++L LAL+ H + L + +FT IF E ++K
Sbjct: 636 FALISLKVFEGLIILSILTNTLFLALD--HHEISQTFDEALSIGNLVFTAIFTAEAVLKI 693
Query: 1272 LALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQ 1331
ALG Y + W DF+IV++SLI V + G G+ +T+R +R R R Q
Sbjct: 694 FALGPAGYVKDKWNVFDFLIVIISLIE-VTNITGDAGLSVLRTLRLMRVFRLARI---WQ 749
Query: 1332 GMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD 1378
MR +++ +++++ ++ + +V + IFA++G Q+++ Y D
Sbjct: 750 TMRKLMSIIIKSLSAVAYLTVVLFMVLFIFAVIGKQMYSEYYINSAD 796
Score = 80.6 bits (190), Expect = 4e-13
Identities = 74/291 (25%), Positives = 135/291 (46%), Gaps = 35/291 (12%)
Query: 132 RVAIYILV-HPLFSLFIITTILVNCILMIMP-----TTPTVEST----EVIFTGIYTFES 181
R +++LV H +F FI+ IL + + + M T T ++ E +FT ++T E
Sbjct: 1170 RYGVFLLVQHRIFEFFILAIILASTVCLAMEDIHLETDITRKNVLNILEYVFTSLFTLEM 1229
Query: 182 AVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID----LGNLAALRTFRVLRALK 237
+K + GF Y + W LDFV++ +++V +G + +L ALRT R LR L+
Sbjct: 1230 VLKWIGNGFT----KYFTNWWCVLDFVIVVISWVGIGASAAGTVDSLRALRTLRALRPLR 1285
Query: 238 TVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDG 297
++ G++ +V A+I + ++ +V+ + + VF +MG+Q+Y G +CV G
Sbjct: 1286 AISRWQGMRVVVNALIYCIPSIGNVLCVCLLIWLVFRIMGVQLYKGQF-YRCV---DSSG 1341
Query: 298 SWGNLTDENWERFC-QNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTS 356
+ N T C QN W ++ N G + L F G+
Sbjct: 1342 TAYNATFVPNRTICLQNNFTWTTPPINFDNVVN---------GMIAL--FQVATFEGWIE 1390
Query: 357 FDTFGWAFLSAFRLMTQDYWENLYQLFFVVIIFLGSFYLVNLILAIVAMSY 407
+ + T+ Y FF+ ++ +GSF+++NLI+ ++ S+
Sbjct: 1391 VMSDASDTDGVYNQPTRGANPYSYVFFFIFVL-IGSFFILNLIVGVIIESF 1440
Score = 66.9 bits (156), Expect = 5e-09
Identities = 46/177 (25%), Positives = 87/177 (49%), Gaps = 14/177 (7%)
Query: 115 FSATNALWILDP-FNPIRRVAIYILVHPLFSLFIITTILVNCILMIMP---TTPTVEST- 169
F+ W P F ++ ++ +F II +IL N + + + + T +
Sbjct: 615 FNKIFCAWECHPAFKKFQKFLFALISLKVFEGLIILSILTNTLFLALDHHEISQTFDEAL 674
Query: 170 ---EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDF--VVIALAYVTMGIDLGNL 224
++FT I+T E+ +K+ A G P Y++D WN DF V+I+L VT L
Sbjct: 675 SIGNLVFTAIFTAEAVLKIFALG----PAGYVKDKWNVFDFLIVIISLIEVTNITGDAGL 730
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+ LRT R++R + I ++ ++ +I+S+ + + ++ L +FA++G Q+Y
Sbjct: 731 SVLRTLRLMRVFRLARIWQTMRKLMSIIIKSLSAVAYLTVVLFMVLFIFAVIGKQMY 787
Score = 58.4 bits (135), Expect = 2e-06
Identities = 26/60 (43%), Positives = 37/60 (61%)
Query: 772 FCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGN 831
FC W+C + +FQK++ L+ E I L I+ NTLF+ALDHH + + D+AL GN
Sbjct: 619 FCAWECHPAFKKFQKFLFALISLKVFEGLIILSILTNTLFLALDHHEISQTFDEALSIGN 678
Score = 52.4 bits (120), Expect = 1e-04
Identities = 39/191 (20%), Positives = 86/191 (45%), Gaps = 20/191 (10%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT-------TPTVESTEVIFTGIYT 178
P N + ++ H F + + I++N + + M + ++ FT ++
Sbjct: 1483 PRNALLLKIFKLVTHSKFEVVVFVVIVLNMLTLGMEHYRMSQNWADALRYVDIGFTSLFA 1542
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAY--------VTMGIDLGNLAALRTF 230
E+ +K+ Y RDA+N DFVV+ L+ +T+ + L +R F
Sbjct: 1543 VEAFLKLCGTRLY-----YFRDAFNVFDFVVVLLSITGFILEELLTLLVSPTLLRVVRVF 1597
Query: 231 RVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCV 290
RV R L+ + G++ ++ ++ S+ L ++ ++ + +FA++G+ +M V + +
Sbjct: 1598 RVFRVLRVIRAARGIRRLILTLMISLPPLFNIAVILGVFMVIFAILGMSFFMNVKLRGAL 1657
Query: 291 KVFPEDGSWGN 301
++GN
Sbjct: 1658 NDIVNFRTFGN 1668
Score = 47.6 bits (108), Expect = 0.003
Identities = 40/171 (23%), Positives = 83/171 (48%), Gaps = 22/171 (12%)
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKI 1587
+ I ++ FD +ML I +N + LD E + +Y +F I+S E ++K+
Sbjct: 153 LALRITINQFFDYFVMLTIIVNCAFLALD----DEIIES--EY---VFTAIYSLEMIIKM 203
Query: 1588 FAL-----RYHYFVEPWNLFDFVVVMFSILSLVLSDII---EKYFVSPTLLRVVRVAKVG 1639
A ++ Y + WN DFVVV+ + ++++ + + + VS LR RV +
Sbjct: 204 LARGFVLNKFTYLRDLWNWLDFVVVVLAYVTIISTSVTPAGSNFNVSG--LRTFRVLRAF 261
Query: 1640 RVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHV 1690
+ +V G++T++ AL SL L + +++ ++ + ++ + + V
Sbjct: 262 KSFTIV---PGLKTIVNALLQSLKPLAEVMVIMIFLVVVISLIALQAYQGV 309
Score = 36.3 bits (80), Expect = 8.5
Identities = 17/69 (24%), Positives = 37/69 (53%)
Query: 822 DMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
D +AL++ LR + W + ++++ + + ++GN+ V +I +F +MG+QL+
Sbjct: 1270 DSLRALRTLRALRPLRAISRWQGMRVVVNALIYCIPSIGNVLCVCLLIWLVFRIMGVQLY 1329
Query: 882 GKNYVDYVD 890
+ VD
Sbjct: 1330 KGQFYRCVD 1338
>UniRef50_UPI0000F2D000 Cluster: PREDICTED: similar to voltage-gated
sodium channel type IV alpha subunit; n=2; Monodelphis
domestica|Rep: PREDICTED: similar to voltage-gated sodium
channel type IV alpha subunit - Monodelphis domestica
Length = 1853
Score = 612 bits (1511), Expect = e-173
Identities = 304/756 (40%), Positives = 479/756 (63%), Gaps = 21/756 (2%)
Query: 1169 DEDVVDDTPADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMI 1228
++ + D P C C ++FP+ S + W LR ++ + + FE +++ ++
Sbjct: 1017 NKSLKSDEPGACFTYGCIRRFPYCKASKKSRKGKIWWNLRKTCYRTVNHGCFEISIVFIV 1076
Query: 1229 LLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLD 1288
LLS AL ED+++ R ++ IL Y + IFT IF +EML+KW+A G++ YF+N WCWL+
Sbjct: 1077 LLSCFALIFEDIYIEKRKTIKIILEYGNMIFTYIFILEMLLKWMAYGYKTYFSNVWCWLE 1136
Query: 1289 FIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIF 1348
F++V VSL+ VA G + TL++LR LR +S +G+RVV++ ++AIPSI
Sbjct: 1137 FLVVNVSLVCLVANYLG------YSEFGTLKSLRILRILSIYEGVRVVLHIFLKAIPSIL 1190
Query: 1349 NVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNH-TTLSHEIIPDKNACT-LENYT----W 1402
LLV LI WL+F++MGV LFAGK+FKC+++ L +I D C L N + W
Sbjct: 1191 EALLVWLICWLLFSLMGVNLFAGKFFKCINITTGERLPWTLIIDVIDCKMLSNSSGDVQW 1250
Query: 1403 ENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXX 1462
+N NFD++G Y L Q+ TFKGW+ I+ A+D+ +V RQP E+N+Y+YLY
Sbjct: 1251 KNPKANFDNIGNGYFSLLQLVTFKGWLDIIYAAVDTVDVERQPKNESNVYIYLYFVIFVI 1310
Query: 1463 XXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPR 1522
F+ V+I++ +QK+K GG L +FMTE+QK YYN +KK +KP K+IPRP
Sbjct: 1311 LGLCFPFVFFVRVVINHLKQQKRKVGG-LGIFMTENQKNYYNMLKKSRYRKPQKSIPRPE 1369
Query: 1523 WRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSE 1582
+ Q +F+++T + F++ I++ I LN + M ++ Q +L +N++FI +F+ E
Sbjct: 1370 NKFQGYIFDLITKEAFEITIIVLICLNTVVMMVETDTQDTYKRNILYQINLVFIGLFAGE 1429
Query: 1583 CLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVL 1642
CLLK+ LR +YF WN+FDFVV+ SI+ ++L + KY ++ + ++V+R+ + GRVL
Sbjct: 1430 CLLKLIGLRLYYFTIGWNIFDFVVIHLSIMVVLLPHLTVKYLLTYSQVQVIRLIRCGRVL 1489
Query: 1643 RLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNF 1702
+KG K + L++AL +SLP L NI LLL L+MFI+AI GMS F ++K G++D++NF
Sbjct: 1490 NFIKGTKVLGPLIYALMLSLPTLLNIVLLLLLIMFIYAILGMSHFAYIKKDAGINDMFNF 1549
Query: 1703 KTFVQSMILLFQMSTSAGWDGVLDGIIN--EEECDLPDNERGS--PGNCGSATIGITYLL 1758
+TF SM+ LFQ++T AGW+G+L+ +++ +CD GS G+CGS + G+ Y +
Sbjct: 1550 ETFGNSMLCLFQITTFAGWNGLLEPVLSTGPPDCDPEKIHPGSSVKGDCGSPSFGVFYFV 1609
Query: 1759 SYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQ 1818
SY++ISFL+++N++I VILE + TE+ + L+++ +D +YE+W++FDPDG+ +I Y Q
Sbjct: 1610 SYIIISFLVLVNLFIVVILEICNVVTEENAQLLSEEVFDNFYEVWKQFDPDGTHFIDYSQ 1669
Query: 1819 LSDFLDVLEPPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTKDFF--ARKGNPI-- 1874
LS+F L+PP I KPNK ++ +MD+P+ +GD +FC D+L A TK + + N I
Sbjct: 1670 LSEFAASLDPPFLIAKPNKIQLTAMDLPMVKGDRVFCADVLIAFTKCVMRESEEFNHICL 1729
Query: 1875 EETGDLEVGRPEEAGYEPVSSTLWRQREEYCARLIQ 1910
+ YEPV++TL R++EE A +IQ
Sbjct: 1730 PLRKHFLSSCLFQVSYEPVTTTLKRKQEEVSALVIQ 1765
Score = 314 bits (772), Expect = 1e-83
Identities = 166/380 (43%), Positives = 244/380 (64%), Gaps = 36/380 (9%)
Query: 62 QPDATLEQGLPLPVRMQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNAL 121
+P + LE G L + G P E+ S PLED+DP+Y ++ TF+V+++G+ IFRFSAT+AL
Sbjct: 33 EPSSDLEAGEQLAF-IYGDVPSEMVSEPLEDLDPYYKDKKTFLVLNEGRIIFRFSATSAL 91
Query: 122 WILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPT-VESTEVIFTGIYTFE 180
+IL PFN IRR+ I +LV+ LF++FI+ T L+NCI + + T+PT ++S + F G+YTFE
Sbjct: 92 YILTPFNLIRRLCIKVLVNFLFNMFIMGTFLINCIFLTLCTSPTWIKSLNLPFLGLYTFE 151
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVA 240
+K++ARGF + PFT+L D WNW D ++ +AY+ + ++LG+ L F VLR +K V+
Sbjct: 152 ILIKILARGFCIGPFTFLSDPWNWFDIPILTMAYLRLFVNLGSFPYLGIFSVLRIMKAVS 211
Query: 241 IVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGS-- 298
+ G +++V + +S+K + ++L +F LSVFA+MG+Q++MG L QKCV+ +G+
Sbjct: 212 LNIGPRSVVRTLTQSMKMFQQTVMLIVFCLSVFAVMGMQLFMGKLKQKCVQWPRGEGNIT 271
Query: 299 ---WGN--------------LTDENWER--FCQNETNWYGEG-GDYPLCGNSSGAGQCEP 338
W N D NW QN +Y EG D LCGNSS +G C
Sbjct: 272 EIPWDNEGIPLLGLGPKDILKRDINWNNKYLDQNNYFYYLEGQKDALLCGNSSYSGDCPE 331
Query: 339 GYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ-----------LFFVVI 387
GY+C++ G NP++ YTSFD FGW+ L+ FRLMT D WENLYQ +FF+V+
Sbjct: 332 GYMCVKA-GMNPDHNYTSFDHFGWSLLTLFRLMTLDCWENLYQQILRAAGKTYVIFFIVV 390
Query: 388 IFLGSFYLVNLILAIVAMSY 407
+ SFYLV LILA+V ++Y
Sbjct: 391 LLFCSFYLVTLILAMVILAY 410
Score = 120 bits (290), Expect = 3e-25
Identities = 65/172 (37%), Positives = 95/172 (55%), Gaps = 5/172 (2%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
L VFK+AK WPT LI I+ ++ AL L +L I +F FAV+GM+LFG+ +Y+ +
Sbjct: 722 LLVFKVAKYWPTWEKLIKIINYSVDALKGLFLLLFITMFTFAVVGMKLFGQGCQEYLCK- 780
Query: 893 PDGDLP--RWNFTDFMHSFMIVFRVLCGEWIESMWDCM-LVGDVSCIPFFLATVVIXXXX 949
D D P RW+ DF HSF+++FRVLCGEWI+SMWDCM G C+ FF+ ++I
Sbjct: 781 TDVDCPFKRWHMHDFFHSFLLMFRVLCGEWIDSMWDCMNTEGQKECLIFFVVVIIIGKMQ 840
Query: 950 XXXXXXXXXXXXXXXXXXXTPTADQDTNKIAEAFNRISRFIDWIKRNVADFL 1001
+ ++N + A RI + I ++KR + D +
Sbjct: 841 LLVLFVALLSSFSPENFAAIQVS-PESNNLQLAMARIQKGIYYVKRTLFDLV 891
Score = 86.6 bits (205), Expect = 6e-15
Identities = 56/160 (35%), Positives = 85/160 (53%), Gaps = 9/160 (5%)
Query: 1529 VFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIF 1588
++ +V D FD+ I + I +N+ M ++HY +E F VL ++FI I+ +E LKI
Sbjct: 619 IYAVVMDPFFDLAIAICIIINITFMAMEHYPMTEKFYNVLSVGYLVFIGIYIAEMFLKII 678
Query: 1589 ALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKG 1647
AL Y+YF WN+FD V+V+ L L+DI K +L R+ V ++ K
Sbjct: 679 ALHPYNYFQRGWNIFDTVIVI-----LALADIYMKEAYGLSLFGWFRLL---LVFKVAKY 730
Query: 1648 AKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
L+ + S+ AL + LLLF+ MF FA+ GM F
Sbjct: 731 WPTWEKLIKIINYSVDALKGLFLLLFITMFTFAVVGMKLF 770
Score = 66.5 bits (155), Expect = 7e-09
Identities = 39/172 (22%), Positives = 89/172 (51%), Gaps = 14/172 (8%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMI-----MPTTPTV----ESTEVIFTGIYTFE 180
+R+ + H F + I+ +L++C +I + T+ E +IFT I+ E
Sbjct: 1055 LRKTCYRTVNHGCFEISIVFIVLLSCFALIFEDIYIEKRKTIKIILEYGNMIFTYIFILE 1114
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVA 240
+K MA G+ TY + W WL+F+V+ ++ V + + + T + LR L+ ++
Sbjct: 1115 MLLKWMAYGYK----TYFSNVWCWLEFLVVNVSLVCLVANYLGYSEFGTLKSLRILRILS 1170
Query: 241 IVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKV 292
I G++ ++ ++++ ++ + +++ + +F+LMG+ ++ G KC+ +
Sbjct: 1171 IYEGVRVVLHIFLKAIPSILEALLVWLICWLLFSLMGVNLFAGKFF-KCINI 1221
Score = 63.3 bits (147), Expect = 6e-08
Identities = 45/177 (25%), Positives = 81/177 (45%), Gaps = 13/177 (7%)
Query: 114 RFSATNALWILDPFNPIRRVAIY-ILVHPLFSLFIITTILVNCILMIMPTTPTVESTE-- 170
RF T +W + IY +++ P F L I I++N M M P E
Sbjct: 598 RFGTTFTIWNCSTLWIKFKDFIYAVVMDPFFDLAIAICIIINITFMAMEHYPMTEKFYNV 657
Query: 171 -----VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGNL 224
++F GIY E +K++A L P+ Y + WN D V++ LA + + + L
Sbjct: 658 LSVGYLVFIGIYIAEMFLKIIA----LHPYNYFQRGWNIFDTVIVILALADIYMKEAYGL 713
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+ FR+L K P + ++ + SV L+ + +L ++ FA++G++++
Sbjct: 714 SLFGWFRLLLVFKVAKYWPTWEKLIKIINYSVDALKGLFLLLFITMFTFAVVGMKLF 770
Score = 62.5 bits (145), Expect = 1e-07
Identities = 22/59 (37%), Positives = 38/59 (64%)
Query: 772 FCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSG 830
F +W+C LW++F+ ++ +V DPF +L I +CI++N FMA++H+ M + L G
Sbjct: 603 FTIWNCSTLWIKFKDFIYAVVMDPFFDLAIAICIIINITFMAMEHYPMTEKFYNVLSVG 661
Score = 56.4 bits (130), Expect = 7e-06
Identities = 37/158 (23%), Positives = 77/158 (48%), Gaps = 7/158 (4%)
Query: 1212 FKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKW 1271
+ ++ + +F+ A+ I+++ +A+E H P ++L +F I+ EM +K
Sbjct: 620 YAVVMDPFFDLAIAICIIINITFMAME--HYPMTEKFYNVLSVGYLVFIGIYIAEMFLKI 677
Query: 1272 LALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQ 1331
+AL YF W D +IV+++L + + A G+ F R L + + +
Sbjct: 678 IALHPYNYFQRGWNIFDTVIVILALADIY--MKEAYGLSLFGWFRLLLVFKVAKYWPTWE 735
Query: 1332 GMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
+ ++N V A+ +F +L + + FA++G++LF
Sbjct: 736 KLIKIINYSVDALKGLFLLLFITM---FTFAVVGMKLF 770
Score = 53.2 bits (122), Expect = 7e-05
Identities = 43/126 (34%), Positives = 66/126 (52%), Gaps = 15/126 (11%)
Query: 1259 FTVIFFIEMLIKWLALGFQ----KYFTNAWCWLDF-IIVMVSLINFVAALCGAGGIQAFK 1313
F ++ E+LIK LA GF + ++ W W D I+ M L FV + +F
Sbjct: 144 FLGLYTFEILIKILARGFCIGPFTFLSDPWNWFDIPILTMAYLRLFV-------NLGSFP 196
Query: 1314 TMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWL-IFAIMGVQLFAGK 1372
+ LR ++A+S G R VV L Q++ +F ++ ++F L +FA+MG+QLF GK
Sbjct: 197 YLGIFSVLRIMKAVSLNIGPRSVVRTLTQSM-KMFQQTVMLIVFCLSVFAVMGMQLFMGK 255
Query: 1373 Y-FKCV 1377
KCV
Sbjct: 256 LKQKCV 261
Score = 46.0 bits (104), Expect = 0.011
Identities = 39/166 (23%), Positives = 76/166 (45%), Gaps = 20/166 (12%)
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKI 1587
+ +++ + F+M IM +N + +TL T + LN+ F+ +++ E L+KI
Sbjct: 103 LCIKVLVNFLFNMFIMGTFLINCIFLTLC------TSPTWIKSLNLPFLGLYTFEILIKI 156
Query: 1588 FALRY-----HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVL 1642
A + + +PWN FD ++ + L L FV+ + + V R++
Sbjct: 157 LARGFCIGPFTFLSDPWNWFDIPILTMAYLRL---------FVNLGSFPYLGIFSVLRIM 207
Query: 1643 RLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
+ V G R+++ L S+ +L+ + +FA+ GM FM
Sbjct: 208 KAVSLNIGPRSVVRTLTQSMKMFQQTVMLIVFCLSVFAVMGMQLFM 253
Score = 43.2 bits (97), Expect = 0.074
Identities = 36/169 (21%), Positives = 81/169 (47%), Gaps = 21/169 (12%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPT-------VESTEVIFTGIYT 178
P N + ++ F + II I +N ++M++ T + ++F G++
Sbjct: 1368 PENKFQGYIFDLITKEAFEITIIVLICLNTVVMMVETDTQDTYKRNILYQINLVFIGLFA 1427
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID------LGNLAALRTFRV 232
E +K++ G L FT WN DFVVI L+ + + + L + ++ R+
Sbjct: 1428 GECLLKLI--GLRLYYFTI---GWNIFDFVVIHLSIMVVLLPHLTVKYLLTYSQVQVIRL 1482
Query: 233 LRALKTVAIVPGLKT---IVGAVIESVKNLRDVIILTMFSLSVFALMGL 278
+R + + + G K ++ A++ S+ L ++++L + + ++A++G+
Sbjct: 1483 IRCGRVLNFIKGTKVLGPLIYALMLSLPTLLNIVLLLLLIMFIYAILGM 1531
>UniRef50_O62604 Cluster: Voltage-gated sodium channel alpha subunit;
n=1; Polyorchis penicillatus|Rep: Voltage-gated sodium
channel alpha subunit - Polyorchis penicillatus
(Hydromedusa)
Length = 1695
Score = 611 bits (1510), Expect = e-173
Identities = 310/694 (44%), Positives = 438/694 (63%), Gaps = 14/694 (2%)
Query: 1179 DCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALE 1238
DC CYQ ++PF + W R T +LIE+ YFE ++ +I SSL L E
Sbjct: 870 DCLCTLCYQCSCCYTSYLNAPFRRSWHNARFYTKQLIEHKYFEGVILFLIAFSSLTLVFE 929
Query: 1239 DVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLIN 1298
D+ LP RP L+ L Y + F VIF +E+LIK ALGF KYFTN W LD IV +SL
Sbjct: 930 DIDLPKRPTLEKFLQYCNYFFAVIFTVELLIKLFALGFMKYFTNFWNLLDVFIVCISL-- 987
Query: 1299 FVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFW 1358
++L G G K +R+LR LRPLRA+SR +GM+VVVNAL+ +IPSI NVLLVC++FW
Sbjct: 988 --SSLFGKGA--NLKALRSLRGLRPLRAISRFEGMKVVVNALLYSIPSIANVLLVCVVFW 1043
Query: 1359 LIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLE-----NYTWENSPMNFDHVG 1413
LIF+IMG LF G++F CVD N+T L +I + C E NY+W N +NFD+
Sbjct: 1044 LIFSIMGYNLFGGQFFYCVDGNYTKLPISVIDNMAMCLNETNKAKNYSWVNKNINFDNSI 1103
Query: 1414 KAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFI 1473
+L LFQ AT +GW + M DA DSR V QP N + +Y LNLFI
Sbjct: 1104 NGFLALFQTATLEGWFEAMADAYDSRGVNMQPGVMVNFWNQIYFVVFIILGAFFILNLFI 1163
Query: 1474 GVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIV 1533
GVIIDNFN K++ + +F+T Q+ + N +K KKP + + RP + +A +F+ +
Sbjct: 1164 GVIIDNFNRLKQQYEDGVGIFLTPGQRNWVNTLKAASLKKPSRRLTRPTSKWRAALFDFI 1223
Query: 1534 TDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH 1593
K F+ IM I LNMLTM + H+ QS+ S L+YLN +F IF+ E ++++ A+R
Sbjct: 1224 HTKYFEFFIMSVILLNMLTMMIQHHGQSQQVSLALEYLNFLFTGIFTLEAIIRLTAMRLE 1283
Query: 1594 YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRT 1653
YF N+FDFV+V+FSI +++ + E++FVSP L RVVRV ++GR+LR +GAKGIR
Sbjct: 1284 YFKYGMNVFDFVIVVFSIAVIIMIEYDEEFFVSPGLFRVVRVFRLGRLLRFFEGAKGIRK 1343
Query: 1654 LLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLF 1713
LLF + S PAL NI LLFL+ FI+AI M+ F + +G ++ V NF+TF +SM LLF
Sbjct: 1344 LLFTIVKSAPALSNIGTLLFLITFIYAIMAMNLFGTLAHQGAINKVTNFETFGRSMCLLF 1403
Query: 1714 QMSTSAGWDGVLD-GIINEEECDL--PDNERGSPGNCGSATIGITYLLSYLVISFLIVIN 1770
++ST+AGW+GVLD ++ C++ + S GNCG+ + + + +SY+++ LI+IN
Sbjct: 1404 RISTAAGWNGVLDAAMVGPPLCNVNATPSSSISEGNCGNKFVAVIFFVSYIILIVLIIIN 1463
Query: 1771 MYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPL 1830
MYIAVILEN++QA + G+T+DD + YY +W+ +DP +Q+I+Y QL DF+D L+ PL
Sbjct: 1464 MYIAVILENFNQAQSQDEAGITEDDLEAYYTVWEDYDPKATQFIKYSQLPDFIDALDGPL 1523
Query: 1831 QIHKPNKYKIISMDIPICRGDMMFCVDILDALTK 1864
++ KPN + + DI I C+D++ AL K
Sbjct: 1524 RVPKPNYWFLEQSDIAIKDRHRCHCLDVMTALIK 1557
Score = 270 bits (661), Expect = 3e-70
Identities = 136/320 (42%), Positives = 206/320 (64%), Gaps = 24/320 (7%)
Query: 102 TFVVISK--GKDI-FRFSATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILM 158
TF+V++ GK + FRF +L++ P + IRR IYI H F + I+ TI+ NC+ M
Sbjct: 79 TFMVVANKLGKQVVFRFCKEKSLFLFGPASFIRRFNIYIFTHQYFEIGILLTIVTNCVFM 138
Query: 159 IMPTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMG 218
+ P E IF IYTFE +K++A+GFIL ++YLR+AWNWLDF+V+ L Y+TM
Sbjct: 139 ALSDPPA--EAEFIFAAIYTFEMVIKILAKGFILHKYSYLRNAWNWLDFLVVILGYITMS 196
Query: 219 IDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGL 278
+ NL+ +RTFRVLRALKT++ V GLK +V +++S+K + DV+ILT+F +S+FAL+GL
Sbjct: 197 PHINNLSGIRTFRVLRALKTISTVKGLKAMVNTLMKSMKMMTDVLILTLFFISIFALIGL 256
Query: 279 QIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEP 338
Q++ G L Q+CV GN T E + + N+ N+ + +CGN + + +C+
Sbjct: 257 QLFPGKLRQRCVL------KNGNKTFE--KSWYTNKDNFLYFEKEEVICGNETTSWKCDA 308
Query: 339 GYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENL-----------YQLFFVVI 387
GY+CL G NP +GY S+D F A L++ ++ T DYWE++ Y ++F++
Sbjct: 309 GYICLADAGNNPMHGYVSYDNFLSAMLTSLQVCTLDYWESVFNSVLSAMGEPYMIYFLLA 368
Query: 388 IFLGSFYLVNLILAIVAMSY 407
+FLG FYL+NL+LA+V+ SY
Sbjct: 369 VFLGPFYLLNLVLAVVSASY 388
Score = 121 bits (291), Expect = 2e-25
Identities = 68/198 (34%), Positives = 108/198 (54%), Gaps = 4/198 (2%)
Query: 799 LFITLCIVVNTLFMALDHHNMDKDMDKA-LKSGNYLRVFKLAKSWPTLNLLISIMGRTMG 857
+F L ++V+ + + L + ++ K A LK +RV KLA+SW T+ L+S + +MG
Sbjct: 553 VFDGLLVIVSIIDIVLSNADVVKGNQLAVLKVFRLMRVLKLAQSWKTMGQLLSTIASSMG 612
Query: 858 ALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLC 917
ALGN+T +L +II+IF+V+GMQLFGK Y D PR+NF +F +SFM++FR+LC
Sbjct: 613 ALGNVTVILGLIIYIFSVVGMQLFGKYYNKAELEAAGEDYPRYNFENFGNSFMMIFRILC 672
Query: 918 GEWIESMWDCMLVGDVSCIPFFLATVVIXXXXXXXXXXXXXXXXXXXXXXXTPTADQDTN 977
G+WIE WD + + + I ++ V + D D+
Sbjct: 673 GKWIEPQWDLLNRTNPASI-LYIFFVFVIGRWVVLNLFLALLLSSFGGDALNGGGDDDSE 731
Query: 978 KIAEAFNRISRFIDWIKR 995
K + +R+ R IDW ++
Sbjct: 732 KPKK--SRLKRLIDWTRK 747
Score = 101 bits (243), Expect = 2e-19
Identities = 84/284 (29%), Positives = 137/284 (48%), Gaps = 31/284 (10%)
Query: 1519 PRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVI 1578
P + R Q F V+ F+ I I LN M +HY+ + L+ N IF
Sbjct: 470 PTMKIRVQYFFFVFVSSSAFEGFITFCIMLNTCLMASEHYKMPKKLEDALNVFNYIFTAT 529
Query: 1579 FSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAK 1637
F E KI A Y WN+FD ++V+ SI+ +VLS+ V L V++V +
Sbjct: 530 FCIEMGFKILAFTPKGYIRNRWNVFDGLLVIVSIIDIVLSNAD---VVKGNQLAVLKVFR 586
Query: 1638 VGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLD 1697
+ RVL+L + K + LL +A S+ AL N+ ++L L+++IF++ GM F +K L+
Sbjct: 587 LMRVLKLAQSWKTMGQLLSTIASSMGALGNVTVILGLIIYIFSVVGMQLFGKYYNKAELE 646
Query: 1698 DV------YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSAT 1751
YNF+ F S +++F+ +L G E + DL + R +P +
Sbjct: 647 AAGEDYPRYNFENFGNSFMMIFR---------ILCGKWIEPQWDLLN--RTNPAS----- 690
Query: 1752 IGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDD 1795
I Y+ VI +V+N+++A++L ++ D G DDD
Sbjct: 691 --ILYIFFVFVIGRWVVLNLFLALLLSSFG---GDALNGGGDDD 729
Score = 88.2 bits (209), Expect = 2e-15
Identities = 58/172 (33%), Positives = 94/172 (54%), Gaps = 22/172 (12%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
+ + YFE ++ I+ + + +AL D P + + IF I+ EM+IK LA
Sbjct: 117 IFTHQYFEIGILLTIVTNCVFMALSD------PPAE-----AEFIFAAIYTFEMVIKILA 165
Query: 1274 LGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSR 1329
GF Y NAW WLDF++V++ I + GI RT R LR L+ +S
Sbjct: 166 KGFILHKYSYLRNAWNWLDFLVVILGYITMSPHINNLSGI------RTFRVLRALKTIST 219
Query: 1330 MQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKCVDMN 1380
++G++ +VN L++++ + +VL++ L F IFA++G+QLF GK +CV N
Sbjct: 220 VKGLKAMVNTLMKSMKMMTDVLILTLFFISIFALIGLQLFPGKLRQRCVLKN 271
Score = 82.6 bits (195), Expect = 1e-13
Identities = 65/278 (23%), Positives = 130/278 (46%), Gaps = 27/278 (9%)
Query: 137 ILVHPLFSLFIITTILVNCILMI-----MPTTPTVES----TEVIFTGIYTFESAVKVMA 187
++ H F I+ I + + ++ +P PT+E F I+T E +K+ A
Sbjct: 905 LIEHKYFEGVILFLIAFSSLTLVFEDIDLPKRPTLEKFLQYCNYFFAVIFTVELLIKLFA 964
Query: 188 RGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKT 247
GF+ Y + WN LD ++ ++ ++ NL ALR+ R LR L+ ++ G+K
Sbjct: 965 LGFM----KYFTNFWNLLDVFIVCISLSSLFGKGANLKALRSLRGLRPLRAISRFEGMKV 1020
Query: 248 IVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENW 307
+V A++ S+ ++ +V+++ + +F++MG ++ G CV DG++ L
Sbjct: 1021 VVNALLYSIPSIANVLLVCVVFWLIFSIMGYNLFGGQFFY-CV-----DGNYTKLPISVI 1074
Query: 308 ER--FCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFL 365
+ C NETN + +Y + G++ L + D + +
Sbjct: 1075 DNMAMCLNETN---KAKNYSWVNKNINFDNSINGFLALFQTATLEGWFEAMADAYDSRGV 1131
Query: 366 SAFRLMTQDYWENLYQLFFVVIIFLGSFYLVNLILAIV 403
+ + ++W Q++FVV I LG+F+++NL + ++
Sbjct: 1132 NMQPGVMVNFWN---QIYFVVFIILGAFFILNLFIGVI 1166
Score = 79.4 bits (187), Expect = 9e-13
Identities = 67/278 (24%), Positives = 124/278 (44%), Gaps = 32/278 (11%)
Query: 1212 FKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKW 1271
F + ++ FE + I+L++ +A E +P + L+D L + IFT F IEM K
Sbjct: 481 FVFVSSSAFEGFITFCIMLNTCLMASEHYKMPKK--LEDALNVFNYIFTATFCIEMGFKI 538
Query: 1272 LALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQ 1331
LA + Y N W D ++V+VS+I+ V + ++ R +R L+ +
Sbjct: 539 LAFTPKGYIRNRWNVFDGLLVIVSIIDIVLSNADVVKGNQLAVLKVFRLMRVLKLAQSWK 598
Query: 1332 GMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPD 1391
M +++ + ++ ++ NV ++ + IF+++G+QLF GKY+
Sbjct: 599 TMGQLLSTIASSMGALGNVTVILGLIIYIFSVVGMQLF-GKYY----------------- 640
Query: 1392 KNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNI 1451
N LE + NF++ G +++ +F++ K WI+ D ++ TN
Sbjct: 641 -NKAELEAAGEDYPRYNFENFGNSFMMIFRILCGK-WIEPQWDLLN----------RTNP 688
Query: 1452 YMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGG 1489
LY LNLF+ +++ +F GG
Sbjct: 689 ASILYIFFVFVIGRWVVLNLFLALLLSSFGGDALNGGG 726
Score = 49.6 bits (113), Expect = 9e-04
Identities = 42/161 (26%), Positives = 73/161 (45%), Gaps = 23/161 (14%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL- 1590
I T + F++ I+L I N + M L F IF I++ E ++KI A
Sbjct: 117 IFTHQYFEIGILLTIVTNCVFMALSDPPAEAEF---------IFAAIYTFEMVIKILAKG 167
Query: 1591 ----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVK 1646
+Y Y WN DF+VV+ +++ S I L +R +V R L+ +
Sbjct: 168 FILHKYSYLRNAWNWLDFLVVILGYITM--SPHINN-------LSGIRTFRVLRALKTIS 218
Query: 1647 GAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
KG++ ++ L S+ + ++ +L + IFA+ G+ F
Sbjct: 219 TVKGLKAMVNTLMKSMKMMTDVLILTLFFISIFALIGLQLF 259
Score = 48.8 bits (111), Expect = 0.001
Identities = 37/165 (22%), Positives = 82/165 (49%), Gaps = 18/165 (10%)
Query: 132 RVAIYILVHP-LFSLFIITTILVNCILMIMP-------TTPTVESTEVIFTGIYTFESAV 183
R A++ +H F FI++ IL+N + M++ + +E +FTGI+T E+ +
Sbjct: 1216 RAALFDFIHTKYFEFFIMSVILLNMLTMMIQHHGQSQQVSLALEYLNFLFTGIFTLEAII 1275
Query: 184 KVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM-------GIDLGNLAALRTFRVLRAL 236
++ A L+ F Y + ++++ VV ++A + M + G +R FR+ R L
Sbjct: 1276 RLTA--MRLEYFKYGMNVFDFV-IVVFSIAVIIMIEYDEEFFVSPGLFRVVRVFRLGRLL 1332
Query: 237 KTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+ G++ ++ +++S L ++ L ++A+M + ++
Sbjct: 1333 RFFEGAKGIRKLLFTIVKSAPALSNIGTLLFLITFIYAIMAMNLF 1377
Score = 47.6 bits (108), Expect = 0.003
Identities = 29/116 (25%), Positives = 60/116 (51%), Gaps = 10/116 (8%)
Query: 172 IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLD--FVVIALAYVTMG---IDLGN-LA 225
IFT + E K++A P Y+R+ WN D V++++ + + + GN LA
Sbjct: 525 IFTATFCIEMGFKILA----FTPKGYIRNRWNVFDGLLVIVSIIDIVLSNADVVKGNQLA 580
Query: 226 ALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
L+ FR++R LK + ++ + S+ L +V ++ + +F+++G+Q++
Sbjct: 581 VLKVFRLMRVLKLAQSWKTMGQLLSTIASSMGALGNVTVILGLIIYIFSVVGMQLF 636
Score = 41.1 bits (92), Expect = 0.30
Identities = 19/52 (36%), Positives = 29/52 (55%)
Query: 782 LEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYL 833
+ Q + + V E FIT CI++NT MA +H+ M K ++ AL NY+
Sbjct: 474 IRVQYFFFVFVSSSAFEGFITFCIMLNTCLMASEHYKMPKKLEDALNVFNYI 525
Score = 39.5 bits (88), Expect = 0.91
Identities = 32/112 (28%), Positives = 53/112 (47%), Gaps = 11/112 (9%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGK- 883
+ + G LR F+ AK LL +I+ ++ AL N+ +L +I FI+A+M M LFG
Sbjct: 1324 RVFRLGRLLRFFEGAKG--IRKLLFTIV-KSAPALSNIGTLLFLITFIYAIMAMNLFGTL 1380
Query: 884 NYVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVSC 935
+ +++ NF F S ++FR+ + D +VG C
Sbjct: 1381 AHQGAINKVT-------NFETFGRSMCLLFRISTAAGWNGVLDAAMVGPPLC 1425
>UniRef50_Q17314 Cluster: Sodium channel; n=1; Cyanea capillata|Rep:
Sodium channel - Cyanea capillata (Lion's mane jellyfish)
Length = 1740
Score = 598 bits (1477), Expect = e-169
Identities = 307/712 (43%), Positives = 439/712 (61%), Gaps = 24/712 (3%)
Query: 1164 IKVGADEDVVDDTPADCCP--EQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFE 1221
I++ ++ VDD CC CY + DSP + W +R EN YFE
Sbjct: 914 IEIHREKTYVDDCFCICCYACNCCYTSYL------DSPPRRLWHNVRYICKVTAENKYFE 967
Query: 1222 TAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFT 1281
++ +I SSL L ED+HL + +L+ L Y + F ++F +E +IK + G KYFT
Sbjct: 968 FMILFLIAFSSLTLVFEDIHLSKKVVLKAFLDYCNYFFAIVFTLEFIIKLIGFGVIKYFT 1027
Query: 1282 NAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALV 1341
N W LD IV +SL A+L G + A +R+LRALRPLRA+SR GM+VVVN+LV
Sbjct: 1028 NLWNLLDVFIVAISL----ASLFGNPDLNA---LRSLRALRPLRAVSRFDGMKVVVNSLV 1080
Query: 1342 QAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNAC----TL 1397
+IPSI NVLLVC +FWLIF++MG QLF G +++C+D N L ++ +K+ C TL
Sbjct: 1081 HSIPSIANVLLVCGVFWLIFSVMGFQLFGGTFYRCLDKNQKLLPISVVNNKSECLENATL 1140
Query: 1398 ENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYX 1457
YTW N +NFD+ +L LFQ AT +GW ++M DA D+R V +QP N + LY
Sbjct: 1141 TGYTWINRDINFDNSISGFLALFQTATLEGWFEVMQDAYDNRGVYQQPEMNANFWTQLYF 1200
Query: 1458 XXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKA 1517
LNLFIGVIIDNFN K++ + +F+T Q+ + N +K KKP +
Sbjct: 1201 VIFIVLGAFFILNLFIGVIIDNFNRLKQQYEDGVGIFLTPGQRNWVNTLKSAAGKKPTRR 1260
Query: 1518 IPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIV 1577
+ RP+ + +A +F+ + K+F++ IM I NMLTM + HY Q++ L+YLN +F
Sbjct: 1261 LTRPKSKWRATLFDFIGKKQFELFIMSVIIANMLTMMIQHYDQTKEVEVALNYLNYLFTG 1320
Query: 1578 IFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVL---SDIIEKYFVSPTLLRVVR 1634
IF+ E ++++ A+R YF N+FDF +V+ SI +V + SP LLRV+R
Sbjct: 1321 IFTIEAIIRLVAMRLEYFKSFMNIFDFTIVLISIAVIVYESSKSSTDNLDFSPGLLRVIR 1380
Query: 1635 VAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKG 1694
V ++GR+LR GAKGIR LLF + S PAL NI LLFLVMFI+A+ GM+FFM+V + G
Sbjct: 1381 VFRLGRLLRFFDGAKGIRQLLFTIVKSAPALLNIGTLLFLVMFIYAVMGMNFFMYVAETG 1440
Query: 1695 GLDDVYNFKTFVQSMILLFQMSTSAGWDGVLD-GIINEEECD-LPDNERGSPGNCGSATI 1752
+ V NFKTF SM LLF++ST+AGW+GVL+ ++ +C L E + NCGS +
Sbjct: 1441 AFNQVVNFKTFGSSMCLLFRISTAAGWNGVLEAAMVQPPKCSKLKTAELNNNSNCGSPIL 1500
Query: 1753 GITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQ 1812
I Y +SY+ + LI+INMYIAVILEN++QA + G+T+DD + YY +W++FDP +Q
Sbjct: 1501 AIIYFVSYIALIVLIMINMYIAVILENFNQAQSQDEAGITEDDLEAYYSVWEQFDPKATQ 1560
Query: 1813 YIRYDQLSDFLDVLEPPLQIHKPNKYKIISMDIPICRGDMMFCVDILDALTK 1864
YI+Y QLSDF+D L+ PL++ KPN + + +IP+ + C+D++ AL K
Sbjct: 1561 YIKYYQLSDFMDELDGPLKVPKPNYWFLEENEIPVKDRHRVHCLDVMAALIK 1612
Score = 276 bits (676), Expect = 5e-72
Identities = 137/340 (40%), Positives = 217/340 (63%), Gaps = 25/340 (7%)
Query: 82 PLELASTPLEDIDPFYHNQTTFVVISK--GKD-IFRFSATNALWILDPFNPIRRVAIYIL 138
P + PL+D D N TFVV++ GK ++RFS +L+++ N R+V + I+
Sbjct: 83 PQSMLGRPLKDFDSEQEN--TFVVVNNRLGKQTVYRFSTDKSLYLMGTNNLARKVFVRIV 140
Query: 139 VHPLFSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYL 198
+ +F +FI+ TI+ NC+ M + P + +E +F IYTFE VK+ A+GFIL ++YL
Sbjct: 141 TNQIFEIFILLTIITNCVFMALSDPP--KESEYVFAAIYTFEVIVKISAKGFILHKYSYL 198
Query: 199 RDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKN 258
R++WNWLDF V+ + YVTM ++ + ++TFRVLRALKT++ V GLK +V +++S++
Sbjct: 199 RNSWNWLDFFVVIVGYVTMIPEMNKYSGVKTFRVLRALKTISTVKGLKAMVNTLLKSMRM 258
Query: 259 LRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWY 318
+ DV+ILT+F +++FAL+GLQ+++G L +CV P D N++ N + F N +WY
Sbjct: 259 MTDVLILTLFFIAIFALIGLQLFIGSLRSRCV---PTD---RNISVFN-KAFYTNSQHWY 311
Query: 319 GEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWEN 378
+ +CGN+S A C P Y+C+ G G NP GY S+D F A L++ ++ T DYWE+
Sbjct: 312 HYNDEEVICGNASTAWNCPPNYLCMPGAGSNPKNGYVSYDNFLLAMLTSLQVCTLDYWES 371
Query: 379 -----------LYQLFFVVIIFLGSFYLVNLILAIVAMSY 407
+Y ++F++ +FLG FYL+NL+LA+V+ SY
Sbjct: 372 VYNSVIAANGEVYMIYFLLAVFLGPFYLLNLVLAVVSASY 411
Score = 126 bits (303), Expect = 8e-27
Identities = 68/164 (41%), Positives = 94/164 (57%), Gaps = 7/164 (4%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LRV KLA+SW T+ L+S +G ++GALGN+T +L III+IFAV+GMQLFG Y + F
Sbjct: 611 LRVLKLAQSWKTMGQLLSTIGNSIGALGNITVILGIIIYIFAVVGMQLFGNKYTLAI--F 668
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVSCIPFFLATVVIXXXXXXX 952
P G +PR+NF +F +SFM++FR+LCG+WIE WD + + I F VI
Sbjct: 669 PKG-VPRYNFNNFGNSFMMIFRILCGKWIEPQWDLLKATSAASIIFIFMVFVIGRWVVLN 727
Query: 953 XXXXXXXXXXXXXXXXTPTADQDTNKIAE-AFNRISRFIDWIKR 995
+D D + AE +R+ + IDW KR
Sbjct: 728 LFLALLLNSFGGDAL---KSDDDEDGTAEKKKSRLQKLIDWTKR 768
Score = 99.1 bits (236), Expect = 1e-18
Identities = 83/290 (28%), Positives = 140/290 (48%), Gaps = 29/290 (10%)
Query: 1497 EDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLD 1556
+ +KK +G L P R + I++ V F+ I I +N + M +
Sbjct: 471 KSEKKESVVSTDVGKPPELGDRPSCFMRFRVIMYIFVGSTWFEGFITGCIMVNTIAMAAE 530
Query: 1557 HYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLV 1615
H++Q E + + D LN IF IF E K+ AL Y WNLFD +V+ S+ L+
Sbjct: 531 HFEQPEVMTKMSDILNYIFTSIFVIEMTCKLIALTPRGYAKNRWNLFDGFLVLASLFDLI 590
Query: 1616 LSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLV 1675
LS + VS + L V+RV ++ RVL+L + K + LL + S+ AL NI ++L ++
Sbjct: 591 LSQL---KLVSGSSLSVMRVFRLLRVLKLAQSWKTMGQLLSTIGNSIGALGNITVILGII 647
Query: 1676 MFIFAIFGMSFF-----MHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIIN 1730
++IFA+ GM F + + KG YNF F S +++F+ +L G
Sbjct: 648 IYIFAVVGMQLFGNKYTLAIFPKG--VPRYNFNNFGNSFMMIFR---------ILCGKWI 696
Query: 1731 EEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENY 1780
E + DL ++ I ++ VI +V+N+++A++L ++
Sbjct: 697 EPQWDLLK---------ATSAASIIFIFMVFVIGRWVVLNLFLALLLNSF 737
Score = 86.2 bits (204), Expect = 8e-15
Identities = 55/188 (29%), Positives = 99/188 (52%), Gaps = 23/188 (12%)
Query: 1196 DDSPFWQGWGTLRLKTF-KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYY 1254
D S + G L K F +++ N FE ++ I+ + + +AL D P +
Sbjct: 120 DKSLYLMGTNNLARKVFVRIVTNQIFEIFILLTIITNCVFMALSD---PPKE-------- 168
Query: 1255 MDRIFTVIFFIEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQ 1310
+ +F I+ E+++K A GF Y N+W WLDF +V+V + + + G++
Sbjct: 169 SEYVFAAIYTFEVIVKISAKGFILHKYSYLRNSWNWLDFFVVIVGYVTMIPEMNKYSGVK 228
Query: 1311 AFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
F R LR L+ +S ++G++ +VN L++++ + +VL++ L F IFA++G+QLF
Sbjct: 229 TF------RVLRALKTISTVKGLKAMVNTLLKSMRMMTDVLILTLFFIAIFALIGLQLFI 282
Query: 1371 GKY-FKCV 1377
G +CV
Sbjct: 283 GSLRSRCV 290
Score = 79.8 bits (188), Expect = 7e-13
Identities = 50/167 (29%), Positives = 86/167 (51%), Gaps = 4/167 (2%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPH-RPILQDILYYMDRIFTVIFFIE 1266
R+ + + +T+FE + I+++++A+A E P + DIL Y IFT IF IE
Sbjct: 500 RVIMYIFVGSTWFEGFITGCIMVNTIAMAAEHFEQPEVMTKMSDILNY---IFTSIFVIE 556
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
M K +AL + Y N W D +V+ SL + + + + MR R LR L+
Sbjct: 557 MTCKLIALTPRGYAKNRWNLFDGFLVLASLFDLILSQLKLVSGSSLSVMRVFRLLRVLKL 616
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
+ M +++ + +I ++ N+ ++ I IFA++G+QLF KY
Sbjct: 617 AQSWKTMGQLLSTIGNSIGALGNITVILGIIIYIFAVVGMQLFGNKY 663
Score = 67.7 bits (158), Expect = 3e-09
Identities = 53/233 (22%), Positives = 108/233 (46%), Gaps = 20/233 (8%)
Query: 173 FTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN--LAALRTF 230
F ++T E +K++ G I Y + WN LD ++A++ ++ GN L ALR+
Sbjct: 1005 FAIVFTLEFIIKLIGFGVI----KYFTNLWNLLDVFIVAISLASL---FGNPDLNALRSL 1057
Query: 231 RVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCV 290
R LR L+ V+ G+K +V +++ S+ ++ +V+++ +F++MG Q++ G +C+
Sbjct: 1058 RALRPLRAVSRFDGMKVVVNSLVHSIPSIANVLLVCGVFWLIFSVMGFQLFGGTF-YRCL 1116
Query: 291 KVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNP 350
++ ++ N + C G Y G++ L
Sbjct: 1117 ---DKNQKLLPISVVNNKSECLENATLTG----YTWINRDINFDNSISGFLALFQTATLE 1169
Query: 351 NYGYTSFDTFGWAFLSAFRLMTQDYWENLYQLFFVVIIFLGSFYLVNLILAIV 403
+ D + + M ++W QL+FV+ I LG+F+++NL + ++
Sbjct: 1170 GWFEVMQDAYDNRGVYQQPEMNANFWT---QLYFVIFIVLGAFFILNLFIGVI 1219
Score = 54.0 bits (124), Expect = 4e-05
Identities = 50/178 (28%), Positives = 84/178 (47%), Gaps = 21/178 (11%)
Query: 132 RVAIYILVHPL-FSLFIITTILVNCILMI-----MPTTPTVEST--EVIFTGIYTFESAV 183
RV +YI V F FI I+VN I M P T S IFT I+ E
Sbjct: 500 RVIMYIFVGSTWFEGFITGCIMVNTIAMAAEHFEQPEVMTKMSDILNYIFTSIFVIEMTC 559
Query: 184 KVMARGFILQPFTYLRDAWNWLD-FVVIALAYVTMGIDL-----GNLAALRTFRVLRALK 237
K++A L P Y ++ WN D F+V+A + + L +L+ +R FR+LR LK
Sbjct: 560 KLIA----LTPRGYAKNRWNLFDGFLVLASLFDLILSQLKLVSGSSLSVMRVFRLLRVLK 615
Query: 238 TVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPE 295
+ ++ + S+ L ++ ++ + +FA++G+Q++ T + +FP+
Sbjct: 616 LAQSWKTMGQLLSTIGNSIGALGNITVILGIIIYIFAVVGMQLFGNKYT---LAIFPK 670
Score = 52.8 bits (121), Expect = 9e-05
Identities = 41/162 (25%), Positives = 79/162 (48%), Gaps = 15/162 (9%)
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTL-DHYQQSETFSAVLDYLNMIFIVIFSSECLLK 1586
+ IVT++ F++ I+L I N + M L D ++SE A + Y + + I + +L
Sbjct: 135 VFVRIVTNQIFEIFILLTIITNCVFMALSDPPKESEYVFAAI-YTFEVIVKISAKGFILH 193
Query: 1587 IFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVK 1646
+Y Y WN DF VV+ ++++ + KY V+ +V R L+ +
Sbjct: 194 ----KYSYLRNSWNWLDFFVVIVGYVTMIPE--MNKY-------SGVKTFRVLRALKTIS 240
Query: 1647 GAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
KG++ ++ L S+ + ++ +L + IFA+ G+ F+
Sbjct: 241 TVKGLKAMVNTLLKSMRMMTDVLILTLFFIAIFALIGLQLFI 282
Score = 51.2 bits (117), Expect = 3e-04
Identities = 41/161 (25%), Positives = 79/161 (49%), Gaps = 24/161 (14%)
Query: 143 FSLFIITTILVNCILMIMPTTPTVESTEV-------IFTGIYTFESAVKVMARGFILQPF 195
F LFI++ I+ N + M++ + EV +FTGI+T E+ ++++A
Sbjct: 1281 FELFIMSVIIANMLTMMIQHYDQTKEVEVALNYLNYLFTGIFTIEAIIRLVA-----MRL 1335
Query: 196 TYLRDAWNWLDF--VVIALAYV--------TMGIDL--GNLAALRTFRVLRALKTVAIVP 243
Y + N DF V+I++A + T +D G L +R FR+ R L+
Sbjct: 1336 EYFKSFMNIFDFTIVLISIAVIVYESSKSSTDNLDFSPGLLRVIRVFRLGRLLRFFDGAK 1395
Query: 244 GLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
G++ ++ +++S L ++ L + ++A+MG+ +M V
Sbjct: 1396 GIRQLLFTIVKSAPALLNIGTLLFLVMFIYAVMGMNFFMYV 1436
Score = 38.3 bits (85), Expect = 2.1
Identities = 22/107 (20%), Positives = 55/107 (51%), Gaps = 1/107 (0%)
Query: 786 KYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMD-KALKSGNYLRVFKLAKSWPT 844
+++ L+ ++ F L +++ +A+ ++ + D AL+S LR + +
Sbjct: 1012 EFIIKLIGFGVIKYFTNLWNLLDVFIVAISLASLFGNPDLNALRSLRALRPLRAVSRFDG 1071
Query: 845 LNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDR 891
+ ++++ + ++ ++ N+ V + IF+VMG QLFG + +D+
Sbjct: 1072 MKVVVNSLVHSIPSIANVLLVCGVFWLIFSVMGFQLFGGTFYRCLDK 1118
>UniRef50_Q01118 Cluster: Sodium channel protein type 7 subunit alpha;
n=23; Eutheria|Rep: Sodium channel protein type 7 subunit
alpha - Homo sapiens (Human)
Length = 1682
Score = 596 bits (1471), Expect = e-168
Identities = 302/721 (41%), Positives = 460/721 (63%), Gaps = 21/721 (2%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W +R K++EN +F+ + + LLS+ LA ED+++ R ++ +L Y D IFT IF
Sbjct: 920 WQNIRKTCCKIVENNWFKCFIGLVTLLSTGTLAFEDIYIDQRKTIKILLEYADMIFTYIF 979
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRP 1323
+EML+KW+A GF+ YF+N W LDF++V+V F +L G + K + +++ LRP
Sbjct: 980 ILEMLLKWMAYGFKAYFSNGWYRLDFVVVIV----FCLSLIGKTR-EELKPLISMKFLRP 1034
Query: 1324 LRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD--MNH 1381
LR +S+ + M+VVV AL++ NV LVCL+ WLIF+IMGV LFAG++++C+D
Sbjct: 1035 LRVLSQFERMKVVVRALIKTTLPTLNVFLVCLMIWLIFSIMGVDLFAGRFYECIDPTSGE 1094
Query: 1382 TTLSHEIIPDKNACTL----ENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAID 1437
S E++ +K+ C E+ WEN+ MNFD+VG +L L QVATF GWI IMN AID
Sbjct: 1095 RFPSSEVM-NKSRCESLLFNESMLWENAKMNFDNVGNGFLSLLQVATFNGWITIMNSAID 1153
Query: 1438 SREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTE 1497
S V QP E NIYMY Y L++ I VIIDNFN+ K K GGS +F+T
Sbjct: 1154 SVAVNIQPHFEVNIYMYCYFINFIIFGVFLPLSMLITVIIDNFNKHKIKLGGS-NIFITV 1212
Query: 1498 DQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDH 1557
Q+K Y +KK+ + + +PRP + Q +F++VT + F++I+M+ I + M +D
Sbjct: 1213 KQRKQYRRLKKLMYEDSQRPVPRPLNKLQGFIFDVVTSQAFNVIVMVLICFQAIAMMIDT 1272
Query: 1558 YQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLS 1617
QS S L ++N IF+++++ EC+LK+ A R YF WN+FDF+VV+FSI L L
Sbjct: 1273 DVQSLQMSIALYWINSIFVMLYTMECILKLIAFRCFYFTIAWNIFDFMVVIFSITGLCLP 1332
Query: 1618 DIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMF 1677
+ Y V P+L++++ ++++ +LRL KG K L+ L +SLPAL NI LL+FLVMF
Sbjct: 1333 MTVGSYLVPPSLVQLILLSRIIHMLRLGKGPKVFHNLMLPLMLSLPALLNIILLIFLVMF 1392
Query: 1678 IFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEE--ECD 1735
I+A+FGM F +VK + G++DV NF+TF SM+ LFQ++ AGWDG+LD I N + +CD
Sbjct: 1393 IYAVFGMYNFAYVKKEAGINDVSNFETFGNSMLCLFQVAIFAGWDGMLDAIFNSKWSDCD 1452
Query: 1736 LPDNERGSP--GNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTD 1793
G+ G+CG+ ++GI Y +SY++IS+LI++NMYI V++E + A++ + L++
Sbjct: 1453 PDKINPGTQVRGDCGNPSVGIFYFVSYILISWLIIVNMYIVVVMEFLNIASKKKNKTLSE 1512
Query: 1794 DDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHKPNKYKIISMDIPICRGDMM 1853
DD+ ++++W+RFDPD +QYI +LSDF L+PPL + KPNK ++I++D+P+ GD +
Sbjct: 1513 DDFRKFFQVWKRFDPDRTQYIDSSKLSDFAAALDPPLFMAKPNKGQLIALDLPMAVGDRI 1572
Query: 1854 FCVDILDALTKDFFARKGNPIEETGDLEVG----RPEEAGYEPVSSTLWRQREEYCARLI 1909
C+DIL A TK + + ++E G P + EP+++TL R++E A +I
Sbjct: 1573 HCLDILLAFTKRVMGQDVRMEKVVSEIESGFLLANPFKITCEPITTTLKRKQEAVSATII 1632
Query: 1910 Q 1910
Q
Sbjct: 1633 Q 1633
Score = 287 bits (703), Expect = 3e-75
Identities = 156/362 (43%), Positives = 218/362 (60%), Gaps = 19/362 (5%)
Query: 62 QPDATLEQGLPLPVRMQGSFPLELASTPLEDIDPFYHNQ-TTFVVISKGKDIFRFSATNA 120
+P+ LE G LP + G+ + S PLED+DP+Y+ + TF+V++K + IFRF+A +
Sbjct: 39 KPNPDLEVGKKLPF-IYGNLSQGMVSEPLEDVDPYYYKKKNTFIVLNKNRTIFRFNAASI 97
Query: 121 LWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVEST-EVIFTGIYTF 179
L L PFN IRR I +LVHP F LFI+ ++L++C+ M + P E GIYTF
Sbjct: 98 LCTLSPFNCIRRTTIKVLVHPFFQLFILISVLIDCVFMSLTNLPKWRPVLENTLLGIYTF 157
Query: 180 ESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTV 239
E VK+ ARG F++L D WNWLDF V + L + L+T R LR LK +
Sbjct: 158 EILVKLFARGVWAGSFSFLGDPWNWLDFSVTVFEVIIRYSPLDFIPTLQTARTLRILKII 217
Query: 240 AIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSW 299
+ GLK++VG +I +K L VIILT+F LS+F+L+G+ ++MG L KC + +P++
Sbjct: 218 PLNQGLKSLVGVLIHCLKQLIGVIILTLFFLSIFSLIGMGLFMGNLKHKCFR-WPQENEN 276
Query: 300 GNLTDENWERFCQNETN--WYGEGGDYP-LCGNSSGAGQCEPGYVCLQGFGPNPNYGYTS 356
L + + ET +Y EG Y LCGN + AGQC GYVC++ G NP+ G+T+
Sbjct: 277 ETLHNRTGNPYYIRETENFYYLEGERYALLCGNRTDAGQCPEGYVCVKA-GINPDQGFTN 335
Query: 357 FDTFGWAFLSAFRLMTQDYWENLYQL-----------FFVVIIFLGSFYLVNLILAIVAM 405
FD+FGWA + FRLM QDY E LY L FFVV+ FL SFY+ +L L I+AM
Sbjct: 336 FDSFGWALFALFRLMAQDYPEVLYHLILYASGKVYMIFFVVVSFLFSFYMASLFLGILAM 395
Query: 406 SY 407
+Y
Sbjct: 396 AY 397
Score = 125 bits (301), Expect = 1e-26
Identities = 56/115 (48%), Positives = 76/115 (66%), Gaps = 2/115 (1%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LR+FKL K WPT +L+ + + AL +L +L IF A GM+LFGKNY ++V
Sbjct: 601 LRIFKLGKYWPTFQILMWSLSNSWVALKDLVLLLFTFIFFSAAFGMKLFGKNYEEFVCHI 660
Query: 893 P-DGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCM-LVGDVSCIPFFLATVVI 945
D LPRW+ DF HSF+ VFR+LCGEW+E++WDCM + G CIPF+L ++I
Sbjct: 661 DKDCQLPRWHMHDFFHSFLNVFRILCGEWVETLWDCMEVAGQSWCIPFYLMVILI 715
Score = 89.4 bits (212), Expect = 9e-16
Identities = 55/169 (32%), Positives = 95/169 (56%), Gaps = 10/169 (5%)
Query: 1521 PRW-RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIF 1579
P W + + V I+ D+ +++ I LN+ +TL+HY S+ + +L+ N++FI IF
Sbjct: 489 PCWLKLKEFVHRIIMAPFTDLFLIICIILNVCFLTLEHYPMSKQTNTLLNIGNLVFIGIF 548
Query: 1580 SSECLLKIFALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKV 1638
++E + KI A+ Y YF WN+FD ++V ++ L L+++ LLR+ R+
Sbjct: 549 TAEMIFKIIAMHPYGYFQVGWNIFDSMIVFHGLIELCLANV-----AGMALLRLFRML-- 601
Query: 1639 GRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
R+ +L K + L+++L+ S AL ++ LLLF +F A FGM F
Sbjct: 602 -RIFKLGKYWPTFQILMWSLSNSWVALKDLVLLLFTFIFFSAAFGMKLF 649
Score = 68.9 bits (161), Expect = 1e-09
Identities = 43/172 (25%), Positives = 89/172 (51%), Gaps = 13/172 (7%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPH-RPILQDILYYMDRIFTVIFFI 1265
+R T K++ + +F+ ++ +L+ + ++L +LP RP+L++ L I+T +
Sbjct: 107 IRRTTIKVLVHPFFQLFILISVLIDCVFMSL--TNLPKWRPVLENTLL---GIYTFEILV 161
Query: 1266 EMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLR 1325
++ + + G + + W WLDF + + +I + L T++T R LR L+
Sbjct: 162 KLFARGVWAGSFSFLGDPWNWLDFSVTVFEVIIRYSPL------DFIPTLQTARTLRILK 215
Query: 1326 AMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKC 1376
+ QG++ +V L+ + + V+++ L F IF+++G+ LF G KC
Sbjct: 216 IIPLNQGLKSLVGVLIHCLKQLIGVIILTLFFLSIFSLIGMGLFMGNLKHKC 267
Score = 62.9 bits (146), Expect = 9e-08
Identities = 40/178 (22%), Positives = 87/178 (48%), Gaps = 13/178 (7%)
Query: 113 FRFSATNALWILDP-FNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTE- 170
++F+ T +W P + ++ I++ P LF+I I++N + + P + T
Sbjct: 476 YKFAKTFLIWNCSPCWLKLKEFVHRIIMAPFTDLFLIICIILNVCFLTLEHYPMSKQTNT 535
Query: 171 ------VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGN 223
++F GI+T E K++A + P+ Y + WN D +++ + + + ++
Sbjct: 536 LLNIGNLVFIGIFTAEMIFKIIA----MHPYGYFQVGWNIFDSMIVFHGLIELCLANVAG 591
Query: 224 LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+A LR FR+LR K P + ++ ++ S L+D+++L + A G++++
Sbjct: 592 MALLRLFRMLRIFKLGKYWPTFQILMWSLSNSWVALKDLVLLLFTFIFFSAAFGMKLF 649
Score = 60.9 bits (141), Expect = 3e-07
Identities = 21/60 (35%), Positives = 38/60 (63%)
Query: 772 FCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGN 831
F +W+C WL+ +++V ++ PF +LF+ +CI++N F+ L+H+ M K + L GN
Sbjct: 482 FLIWNCSPCWLKLKEFVHRIIMAPFTDLFLIICIILNVCFLTLEHYPMSKQTNTLLNIGN 541
Score = 54.0 bits (124), Expect = 4e-05
Identities = 33/119 (27%), Positives = 64/119 (53%), Gaps = 5/119 (4%)
Query: 166 VESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM-GIDLGNL 224
+E ++IFT I+ E +K MA GF Y + W LDFVV+ + +++ G L
Sbjct: 968 LEYADMIFTYIFILEMLLKWMAYGFK----AYFSNGWYRLDFVVVIVFCLSLIGKTREEL 1023
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
L + + LR L+ ++ +K +V A+I++ +V ++ + +F++MG+ ++ G
Sbjct: 1024 KPLISMKFLRPLRVLSQFERMKVVVRALIKTTLPTLNVFLVCLMIWLIFSIMGVDLFAG 1082
Score = 48.4 bits (110), Expect = 0.002
Identities = 32/117 (27%), Positives = 61/117 (52%), Gaps = 16/117 (13%)
Query: 1578 IFSSECLLKIFAL-----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPT-LLR 1631
I++ E L+K+FA + + +PWN DF V +F ++I +Y SP +
Sbjct: 154 IYTFEILVKLFARGVWAGSFSFLGDPWNWLDFSVTVF--------EVIIRY--SPLDFIP 203
Query: 1632 VVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
++ A+ R+L+++ +G+++L+ L L L + +L + IF++ GM FM
Sbjct: 204 TLQTARTLRILKIIPLNQGLKSLVGVLIHCLKQLIGVIILTLFFLSIFSLIGMGLFM 260
Score = 47.6 bits (108), Expect = 0.003
Identities = 47/178 (26%), Positives = 79/178 (44%), Gaps = 14/178 (7%)
Query: 1198 SPFWQGWGTLRLKTF--KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYM 1255
SP W L+LK F ++I + + +I I+L+ L LE H P +L
Sbjct: 488 SPCW-----LKLKEFVHRIIMAPFTDLFLIICIILNVCFLTLE--HYPMSKQTNTLLNIG 540
Query: 1256 DRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTM 1315
+ +F IF EM+ K +A+ YF W D +IV LI LC A + +
Sbjct: 541 NLVFIGIFTAEMIFKIIAMHPYGYFQVGWNIFDSMIVFHGLIE----LCLA-NVAGMALL 595
Query: 1316 RTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
R R LR + ++++ +L + ++ +++L+ F A G++LF Y
Sbjct: 596 RLFRMLRIFKLGKYWPTFQILMWSLSNSWVALKDLVLLLFTFIFFSAAFGMKLFGKNY 653
>UniRef50_A7RP56 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1478
Score = 545 bits (1344), Expect = e-153
Identities = 287/702 (40%), Positives = 425/702 (60%), Gaps = 17/702 (2%)
Query: 1179 DCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALE 1238
DC PE C +G W R + +E+ YFE ++ +++SS L E
Sbjct: 758 DCFPECCMNACGCTSGQQHFC----WLKFRCRVRCFVEHRYFEWFILFTVMVSSFTLVFE 813
Query: 1239 DVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLIN 1298
D+HL +P L+ L +++ +F IF +E ++K + GF YFT+ W LD +IV V +
Sbjct: 814 DIHLHQKPDLERALNFLNFLFAAIFSLEFILKVIGFGFVSYFTSVWNCLDALIVSVCVS- 872
Query: 1299 FVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFW 1358
VA L + F++ RT+R LRPLRA+SR+ GM+VV+NAL AIP I +VL+V ++FW
Sbjct: 873 -VACLFENPNLSVFRSFRTVRGLRPLRAISRLGGMKVVINALFAAIPGIGSVLVVSMLFW 931
Query: 1359 LIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLE-NYTWENSPMNFDHVGKAYL 1417
L+F+I GVQLFAGK++KCV+ LS +IP+K AC +Y W N+ +NFD+V +L
Sbjct: 932 LMFSISGVQLFAGKFYKCVNAEDEKLSPSVIPNKTACLDHPDYRWVNANVNFDNVINGFL 991
Query: 1418 CLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVII 1477
L QVAT++GW+++M DA+DS ++ +QP E N+ Y Y LNLF+GVII
Sbjct: 992 ALLQVATYEGWMEVMADAVDSTKIDQQPSYEANLIAYAYFVVFIIVGSFFVLNLFVGVII 1051
Query: 1478 DNFNEQKKKAG--GSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTD 1535
DNFN KKK S+ M +TE Q+K+ + +KP RP + +F++V+
Sbjct: 1052 DNFNTLKKKYEEINSMGMLLTESQRKWVQILMAAAKRKPPSNRLRPTDCFRGKLFDLVSS 1111
Query: 1536 KKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYF 1595
+F++ I+ I NM M + HY Q + + +Y + + IF E ++KI A+R HYF
Sbjct: 1112 NQFEVFILTVIMCNMGMMMVQHYDQPPLTTVIGNY---VLVGIFLLEAIIKIIAMRLHYF 1168
Query: 1596 VEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLL 1655
+ W++FDFVVV+ SI+ + L E VSP LLRV+RV +V R+LR+V+ AK IR LL
Sbjct: 1169 KKAWSIFDFVVVVSSIVGMYLGMSTESAVVSPGLLRVLRVFRVARLLRVVQFAKRIRQLL 1228
Query: 1656 FALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQM 1715
A+ +S+PALFNI LLFLVMFI+AI GMS F ++K +G L+D+ NF+TF S+IL+F++
Sbjct: 1229 VAIIISMPALFNIGTLLFLVMFIYAIIGMSSFGNIKKQGALNDLVNFETFSSSIILIFRL 1288
Query: 1716 STSAGWDGVLDG-IINEEECDLPDNERGSP-GNCGSATIGITYLLSYLVISFLIVINMYI 1773
T GW+ +LD ++ CD N G P GNCG + YL++Y+V FLI++NMYI
Sbjct: 1289 GTGTGWNDILDALVVQPPHCD--PNFGGLPNGNCGFPIGAVFYLVTYIVSVFLIIVNMYI 1346
Query: 1774 AVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIH 1833
AV+L+N ++A E+ + GL+ D + YY + F G Q++ L +FL L+ P +I
Sbjct: 1347 AVLLDNVNRAHENDEFGLSKDKFKSYYHTFANFSM-GKQFLPLRVLPEFLAALDKPFKIA 1405
Query: 1834 KPNKYKIISMDIPICRGDMMFCVDILDALTKDFFARKGNPIE 1875
P++ I M IP+ GD++ C D+L L K + G E
Sbjct: 1406 HPSEELIRKMKIPVREGDLVHCFDLLKVLVKKILEQHGESPE 1447
Score = 271 bits (664), Expect = 1e-70
Identities = 136/322 (42%), Positives = 201/322 (62%), Gaps = 30/322 (9%)
Query: 102 TFVVISK-----GKDIFRFSATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCI 156
TF+++SK G +RFS T +L L P +P+R I ++ HP F + + ILVNCI
Sbjct: 17 TFLILSKRFNSSGYQAYRFSRTASLLCLGPVHPLRMFCILLITHPYFEIIVTLVILVNCI 76
Query: 157 LMIMPTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVT 216
++ + P E E IFT IYT E K+++RGF+ + YLRD WNWLD +V+ L+Y++
Sbjct: 77 ILGLNDPP--EEAEYIFTAIYTLEMICKIISRGFVKDSYAYLRDTWNWLDSLVVFLSYLS 134
Query: 217 MGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALM 276
+ D+ +L+ +RT RVLRA +T++ + GL+ +V +++ S+K L DV++L +FSL V AL+
Sbjct: 135 LAPDIASLSGIRTLRVLRAFRTISALKGLRAMVNSLLRSLKLLTDVLVLFLFSLCVLALI 194
Query: 277 GLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQC 336
GLQ++ G L KCV N T N N ++WY G+ LCG SS AG+C
Sbjct: 195 GLQLFTGELRNKCVL------ETANATTIN------NPSSWYHREGEPLLCGFSSTAGRC 242
Query: 337 EPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENL-----------YQLFFV 385
Y C+ GPNP++G+T+FD GW+ + AF+++T D+WENL Y ++FV
Sbjct: 243 PANYTCVAHVGPNPDHGFTNFDDIGWSLVMAFQILTMDFWENLYDRVLRSMGEWYMMYFV 302
Query: 386 VIIFLGSFYLVNLILAIVAMSY 407
V IF SFYL+NL+LA+V MSY
Sbjct: 303 VGIFSCSFYLLNLVLAVVYMSY 324
Score = 124 bits (298), Expect = 3e-26
Identities = 52/113 (46%), Positives = 79/113 (69%), Gaps = 2/113 (1%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LRV LA+SW T+ LI + ++ + N+T +L +II++FAV+GM++FG +Y + F
Sbjct: 576 LRVLYLAQSWETMAKLIRAIAHSVDPIFNITCILGVIIYVFAVVGMRVFGPHYT--AEAF 633
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVSCIPFFLATVVI 945
+PRWNFTDF HSFM+VFR+LC EW+E +WDCM V + + + FFL +++
Sbjct: 634 GSRGIPRWNFTDFTHSFMMVFRILCSEWVEPLWDCMRVTNTAALLFFLPALIV 686
Score = 95.9 bits (228), Expect = 1e-17
Identities = 72/278 (25%), Positives = 138/278 (49%), Gaps = 31/278 (11%)
Query: 1524 RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSEC 1583
R + + E + FD II I LN + +T+ ++ + + VLD LN IF +F E
Sbjct: 468 RACSALVEFIQRPLFDGIIAGLILLNTVVLTMYYHGMPDDLTFVLDILNAIFTGLFILEM 527
Query: 1584 LLKIFALRY-HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVL 1642
++KIFA Y WNLFD V+++ S ++ L + T + + R+ ++ RVL
Sbjct: 528 IVKIFAFGLVKYICNKWNLFDSVIIITSAVAYFLG--------TSTGVSIFRILRLLRVL 579
Query: 1643 RLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF--MHVKDKGGLDDV- 1699
L + + + L+ A+A S+ +FNI +L +++++FA+ GM F + + G +
Sbjct: 580 YLAQSWETMAKLIRAIAHSVDPIFNITCILGVIIYVFAVVGMRVFGPHYTAEAFGSRGIP 639
Query: 1700 -YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLL 1758
+NF F S +++F++ S + + D C N T + + L
Sbjct: 640 RWNFTDFTHSFMMVFRILCSEWVEPLWD-------CMRVTN-----------TAALLFFL 681
Query: 1759 SYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDY 1796
L++ IV+N+++A++L ++++ ED+ ++ Y
Sbjct: 682 PALIVGNFIVLNLFVALLLNSFAKKEEDLHREASEQPY 719
Score = 89.8 bits (213), Expect = 7e-16
Identities = 61/187 (32%), Positives = 102/187 (54%), Gaps = 24/187 (12%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
LR+ LI + YFE V +IL++ + L L D P + IFT I+ +E
Sbjct: 50 LRMFCILLITHPYFEIIVTLVILVNCIILGLNDP--PEEA---------EYIFTAIYTLE 98
Query: 1267 MLIKWLALGFQK----YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALR 1322
M+ K ++ GF K Y + W WLD ++V +S ++ + GI RTLR LR
Sbjct: 99 MICKIISRGFVKDSYAYLRDTWNWLDSLVVFLSYLSLAPDIASLSGI------RTLRVLR 152
Query: 1323 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKCV--DM 1379
R +S ++G+R +VN+L++++ + +VL++ L + A++G+QLF G+ KCV
Sbjct: 153 AFRTISALKGLRAMVNSLLRSLKLLTDVLVLFLFSLCVLALIGLQLFTGELRNKCVLETA 212
Query: 1380 NHTTLSH 1386
N TT+++
Sbjct: 213 NATTINN 219
Score = 74.9 bits (176), Expect = 2e-11
Identities = 44/161 (27%), Positives = 83/161 (51%), Gaps = 7/161 (4%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
+ I+ F+ + +ILL+++ L + +P L +L ++ IFT +F +EM++K
Sbjct: 475 EFIQRPLFDGIIAGLILLNTVVLTMYYHGMPDD--LTFVLDILNAIFTGLFILEMIVKIF 532
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG 1332
A G KY N W D +I++ S + + L + G+ F R LR LR L +
Sbjct: 533 AFGLVKYICNKWNLFDSVIIITSAVAYF--LGTSTGVSIF---RILRLLRVLYLAQSWET 587
Query: 1333 MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
M ++ A+ ++ IFN+ + + +FA++G+++F Y
Sbjct: 588 MAKLIRAIAHSVDPIFNITCILGVIIYVFAVVGMRVFGPHY 628
Score = 66.5 bits (155), Expect = 7e-09
Identities = 42/169 (24%), Positives = 86/169 (50%), Gaps = 18/169 (10%)
Query: 140 HPLFSLFIITTILVNCILMI-----MPTTPTVEST----EVIFTGIYTFESAVKVMARGF 190
H F FI+ T++V+ ++ + P +E +F I++ E +KV+ GF
Sbjct: 792 HRYFEWFILFTVMVSSFTLVFEDIHLHQKPDLERALNFLNFLFAAIFSLEFILKVIGFGF 851
Query: 191 ILQPFTYLRDAWNWLDFVVIALAY-VTMGIDLGNLAALRTFRV---LRALKTVAIVPGLK 246
+ +Y WN LD +++++ V + NL+ R+FR LR L+ ++ + G+K
Sbjct: 852 V----SYFTSVWNCLDALIVSVCVSVACLFENPNLSVFRSFRTVRGLRPLRAISRLGGMK 907
Query: 247 TIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPE 295
++ A+ ++ + V++++M +F++ G+Q++ G KCV E
Sbjct: 908 VVINALFAAIPGIGSVLVVSMLFWLMFSISGVQLFAGKF-YKCVNAEDE 955
Score = 57.2 bits (132), Expect = 4e-06
Identities = 43/159 (27%), Positives = 78/159 (49%), Gaps = 20/159 (12%)
Query: 143 FSLFIITTILVNCILMIM-----PTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTY 197
F +FI+T I+ N +M++ P TV V+ GI+ E+ +K++A Y
Sbjct: 1114 FEVFILTVIMCNMGMMMVQHYDQPPLTTVIGNYVL-VGIFLLEAIIKIIA-----MRLHY 1167
Query: 198 LRDAWNWLDFVVIALAYVTMGIDL---------GNLAALRTFRVLRALKTVAIVPGLKTI 248
+ AW+ DFVV+ + V M + + G L LR FRV R L+ V ++ +
Sbjct: 1168 FKKAWSIFDFVVVVSSIVGMYLGMSTESAVVSPGLLRVLRVFRVARLLRVVQFAKRIRQL 1227
Query: 249 VGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQ 287
+ A+I S+ L ++ L + ++A++G+ + + Q
Sbjct: 1228 LVAIIISMPALFNIGTLLFLVMFIYAIIGMSSFGNIKKQ 1266
Score = 56.8 bits (131), Expect = 6e-06
Identities = 40/157 (25%), Positives = 76/157 (48%), Gaps = 16/157 (10%)
Query: 135 IYILVHPLFSLFIITTILVNCILMIM-------PTTPTVESTEVIFTGIYTFESAVKVMA 187
+ + PLF I IL+N +++ M T ++ IFTG++ E VK+ A
Sbjct: 474 VEFIQRPLFDGIIAGLILLNTVVLTMYYHGMPDDLTFVLDILNAIFTGLFILEMIVKIFA 533
Query: 188 RGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKT 247
G + Y+ + WN D V+I + V LG + FR+LR L+ + + +T
Sbjct: 534 FGLV----KYICNKWNLFDSVIIITSAV--AYFLGTSTGVSIFRILRLLRVLYLAQSWET 587
Query: 248 ---IVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
++ A+ SV + ++ + + VFA++G++++
Sbjct: 588 MAKLIRAIAHSVDPIFNITCILGVIIYVFAVVGMRVF 624
Score = 52.8 bits (121), Expect = 9e-05
Identities = 44/157 (28%), Positives = 74/157 (47%), Gaps = 15/157 (9%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTL-DHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL 1590
++T F++I+ L I +N + + L D +++E + L MI +I S +K
Sbjct: 57 LITHPYFEIIVTLVILVNCIILGLNDPPEEAEYIFTAIYTLEMICKII--SRGFVKD--- 111
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
Y Y + WN D +VV S LSL DI L +R +V R R + KG
Sbjct: 112 SYAYLRDTWNWLDSLVVFLSYLSLA-PDIAS--------LSGIRTLRVLRAFRTISALKG 162
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+R ++ +L SL L ++ +L + + A+ G+ F
Sbjct: 163 LRAMVNSLLRSLKLLTDVLVLFLFSLCVLALIGLQLF 199
Score = 41.9 bits (94), Expect = 0.17
Identities = 34/115 (29%), Positives = 58/115 (50%), Gaps = 9/115 (7%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKN 884
+ + LRV + AK LL++I+ +M AL N+ +L +++FI+A++GM FG
Sbjct: 1207 RVFRVARLLRVVQFAKR--IRQLLVAII-ISMPALFNIGTLLFLVMFIYAIIGMSSFG-- 1261
Query: 885 YVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVSCIPFF 939
+ + DL NF F S +++FR+ G + D ++V C P F
Sbjct: 1262 --NIKKQGALNDLV--NFETFSSSIILIFRLGTGTGWNDILDALVVQPPHCDPNF 1312
>UniRef50_UPI000065F7BA Cluster: Homolog of Takifugu pardalis
"Voltage-gated sodium channel.; n=1; Takifugu
rubripes|Rep: Homolog of Takifugu pardalis "Voltage-gated
sodium channel. - Takifugu rubripes
Length = 1613
Score = 503 bits (1240), Expect = e-140
Identities = 276/724 (38%), Positives = 423/724 (58%), Gaps = 53/724 (7%)
Query: 1169 DEDVVDDTPADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKL----IENTYFETAV 1224
D + +DTP +CC ++CY P L D QG G L + K+ ++N + + +
Sbjct: 914 DGEEPEDTPENCCCQRCYSCCPLLNTDPS----QGAGRLCFSSRKICLLIVQNRHVKRFM 969
Query: 1225 ITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAW 1284
++LLSS+ALALEDV+L HRP+L+ +L + F +F +EML+KW+ GF+KYFTNAW
Sbjct: 970 TVVVLLSSVALALEDVYLQHRPVLRTVLSAAELAFGALFLVEMLLKWVGFGFRKYFTNAW 1029
Query: 1285 CWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAI 1344
CWL+F+IV V ++ L AG + TLR LR LR +S QG R+V+ L Q +
Sbjct: 1030 CWLEFLIVAVGVL-----LQPAG-------LGTLRVLRVLRILSIFQGPRLVLGTLFQLV 1077
Query: 1345 PSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCV-DMNHTTLSHEIIPDKNAC---TLENY 1400
P++F LLV L+ WL+F+++GV +FAGK++ C+ + + E + K+ C NY
Sbjct: 1078 PAMFGGLLVILLVWLVFSVVGVNMFAGKFYYCLNETSQEMFLSEEVQTKSECYALIFSNY 1137
Query: 1401 T---WENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYX 1457
T W+NSP FD+V YL LF + K W IM A+DSR V QP+ E + Y +LY
Sbjct: 1138 TEVTWKNSPFTFDNVLMGYLSLFVMGFSKSWRDIMYAAVDSRFVESQPVYEYDPYKWLYF 1197
Query: 1458 XXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKA 1517
TLN FI VI+ + + +FMT+ Q+ Y K+ K P +A
Sbjct: 1198 VFFIINVFF-TLNFFIKVILSALQRKMNE-----HIFMTKHQQIYSKTWMKLFPKSPQRA 1251
Query: 1518 IPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIV 1577
+PRP+ + QA VF++V ++++++ I L+++ + ++ + VL +L+ I+++
Sbjct: 1252 VPRPQNKCQACVFDLVNSPIYEVVMVALICLSVVLLMVESMDLTLGLEIVLHWLHFIYVL 1311
Query: 1578 IFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSIL--------------SLVLSDIIEKY 1623
IF EC+LKI ALR HYF + WN+ DF+V++ I+ S+ + D Y
Sbjct: 1312 IFLIECILKIVALRQHYFKDGWNIIDFIVLLVQIIGKFFMSGSRLMFRDSIFMFDFFYAY 1371
Query: 1624 FVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFG 1683
F+SPT+ ++R+ ++ RVL + + IR LL A SLPALFNI +LF+ M ++++ G
Sbjct: 1372 FISPTIFLLLRLFRITRVLHFIPWTRRIRKLLLAFGKSLPALFNIAFVLFVTMVVYSLIG 1431
Query: 1684 MSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINE-EECDLPDNERG 1742
M F +VK++ +DD +NF+TF S I +F ST+ WDG+L I++ CD G
Sbjct: 1432 MFNFAYVKEEFTIDDFFNFETFCSSFICMFMSSTTTAWDGLLLPIMSRPPSCDPFAEHPG 1491
Query: 1743 SP--GNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYY 1800
S G+C S T+GI + +YL+++FL++I +YIAV LE + +ED EGL+D D +
Sbjct: 1492 SDVIGDCSSPTLGIAFFSTYLLLTFLLLIQLYIAVALEIIN--SEDT-EGLSDIDLQRFC 1548
Query: 1801 EIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHKPNKYKIISMDIPICRGDMMFCVDILD 1860
W+RFDPDG+ I Y +L DF D L+ PL I PN ++ MD+P+ GD + C D+L
Sbjct: 1549 NTWKRFDPDGTDLIPYSKLCDFSDSLQDPLGIPHPNTSRLAHMDLPLYPGDKVHCTDVLL 1608
Query: 1861 ALTK 1864
+L K
Sbjct: 1609 SLAK 1612
Score = 230 bits (563), Expect = 3e-58
Identities = 141/370 (38%), Positives = 211/370 (57%), Gaps = 32/370 (8%)
Query: 61 PQPDATLEQGLPLPVRMQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNA 120
PQP LE+G PLP + G E +TPLE++DP++ ++ TF+V+ KGK I RF+A A
Sbjct: 1 PQPSPELEEGRPLPY-IFGEPSAEHLNTPLEELDPYHQSEKTFLVLGKGKVIHRFNAHKA 59
Query: 121 LWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMP--TTPTVESTEVIFTGIYT 178
++ P NP+R +AI IL + L +F+ TIL+N ++M+ ++P F+ ++
Sbjct: 60 CYLFGPLNPLRTLAIKILTNAL--MFV--TILLNYVVMVTLRYSSPLNLYAGFAFSAVFM 115
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKT 238
E VK+++RG + FT+LR+ WNW D VIA ++ + +F L +
Sbjct: 116 LEVLVKILSRGLCIGKFTFLRNPWNWPDVTVIAAPIKMKMMNFWVSSVPDSFHCLYIFQC 175
Query: 239 VAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVK--VFPED 296
LK ++ ++SVK L V+ILT F L +FA +GLQ +MG L QKC+ +F ++
Sbjct: 176 CWRFLCLKKMLYHFVQSVKRLSCVLILTAFMLCIFATVGLQSFMGNLRQKCISTSLFSQN 235
Query: 297 GSW---------GNLTDENWERFCQNETNWYGEGG--DYPLCGNSSGAGQCEPGYVCLQG 345
+ T N++ + + N Y G D +CGNSS AG C GY+C++
Sbjct: 236 RTSDIYITSYYVNESTAFNYQEYIDDPDNIYFLPGSLDALVCGNSSDAGTCPEGYMCIRA 295
Query: 346 FGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQLF------FVVIIFL-----GSFY 394
G PNY YTS+DTFGW+ LS+FRL+TQ+YWENL QL F ++ FL G F
Sbjct: 296 -GRTPNYSYTSYDTFGWSLLSSFRLLTQEYWENLMQLVLRSAGKFSLVHFLFFVSPGCFV 354
Query: 395 LVNLILAIVA 404
LV+LI+A+ A
Sbjct: 355 LVSLIVAVAA 364
Score = 91.1 bits (216), Expect = 3e-16
Identities = 47/115 (40%), Positives = 69/115 (60%), Gaps = 9/115 (7%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LRVF+LA+SW + + I T+ +F+L I++ F +G QLF ++Y V +
Sbjct: 621 LRVFRLARSWRWFHQFLQI---TL----KFSFLLLIVLLGFVTVGYQLFHRDYRTSVCKI 673
Query: 893 P-DGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLV-GDVSCIPFFLATVVI 945
D LPRW+ F H+F+IVF + G WIES+WDCM V G C+ F+L+ V+I
Sbjct: 674 SHDCSLPRWHMDSFFHTFLIVFGIFSGSWIESLWDCMEVSGPTLCLTFYLSAVII 728
Score = 74.5 bits (175), Expect = 3e-11
Identities = 70/272 (25%), Positives = 127/272 (46%), Gaps = 31/272 (11%)
Query: 1522 RWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSS 1581
RW Q V IVT FD+ I++ I +++L M ++H+ +E F L N++F I++
Sbjct: 512 RWLKQR-VRTIVTSPFFDLGIVVCIVIDVLFMAMEHFPMTEEFQQTLTCANLVFTCIYTV 570
Query: 1582 ECLLKIFAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGR 1640
E ++KI A+ Y YF WN F+ +V S+L L ++D+ L V+RV ++ R
Sbjct: 571 EMVIKIVAMDPYGYFKVSWNTFECTIVAVSLLELCVADV--------EGLSVLRVFRLLR 622
Query: 1641 VLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHV-KDKGGLD-D 1698
V RL + + L + + L I LL F+ + + +F + V K
Sbjct: 623 VFRLARSWRWFHQFL-QITLKFSFLLLIVLLGFVTVG-YQLFHRDYRTSVCKISHDCSLP 680
Query: 1699 VYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLL 1758
++ +F + +++F G+ G E D + T+ +T+ L
Sbjct: 681 RWHMDSFFHTFLIVF---------GIFSGSWIESLWDCME--------VSGPTLCLTFYL 723
Query: 1759 SYLVISFLIVINMYIAVILENYSQATEDVQEG 1790
S ++I L+V+++++ ++L YS EG
Sbjct: 724 SAVIIGNLLVLHLFLVLLLNPYSSNVVSPGEG 755
Score = 60.1 bits (139), Expect = 6e-07
Identities = 35/123 (28%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W L+ + ++ + +F+ ++ I++ L +A+E H P Q L + +FT I+
Sbjct: 511 WRWLKQRVRTIVTSPFFDLGIVVCIVIDVLFMAME--HFPMTEEFQQTLTCANLVFTCIY 568
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINF-VAALCGAGGIQAFKTMRTLRALR 1322
+EM+IK +A+ YF +W + IV VSL+ VA + G ++ F+ +R R R
Sbjct: 569 TVEMVIKIVAMDPYGYFKVSWNTFECTIVAVSLLELCVADVEGLSVLRVFRLLRVFRLAR 628
Query: 1323 PLR 1325
R
Sbjct: 629 SWR 631
Score = 57.2 bits (132), Expect = 4e-06
Identities = 31/109 (28%), Positives = 59/109 (54%), Gaps = 12/109 (11%)
Query: 137 ILVHPLFSLFIITTILVNCILMIMPTTPTVESTE-------VIFTGIYTFESAVKVMARG 189
I+ P F L I+ I+++ + M M P E + ++FT IYT E +K++A
Sbjct: 521 IVTSPFFDLGIVVCIVIDVLFMAMEHFPMTEEFQQTLTCANLVFTCIYTVEMVIKIVA-- 578
Query: 190 FILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGNLAALRTFRVLRALK 237
+ P+ Y + +WN + ++A++ + + + D+ L+ LR FR+LR +
Sbjct: 579 --MDPYGYFKVSWNTFECTIVAVSLLELCVADVEGLSVLRVFRLLRVFR 625
Score = 54.0 bits (124), Expect = 4e-05
Identities = 21/57 (36%), Positives = 34/57 (59%)
Query: 775 WDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGN 831
W+CC W ++ V +V PF +L I +CIV++ LFMA++H M ++ + L N
Sbjct: 505 WNCCGCWRWLKQRVRTIVTSPFFDLGIVVCIVIDVLFMAMEHFPMTEEFQQTLTCAN 561
Score = 53.2 bits (122), Expect = 7e-05
Identities = 35/137 (25%), Positives = 68/137 (49%), Gaps = 11/137 (8%)
Query: 148 ITTILVNCILMIMPTTPTVEST-EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLD 206
+ L + L P TV S E+ F ++ E +K + GF Y +AW WL+
Sbjct: 978 VALALEDVYLQHRPVLRTVLSAAELAFGALFLVEMLLKWVGFGFR----KYFTNAWCWLE 1033
Query: 207 FVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILT 266
F+++A+ + LG T RVLR L+ ++I G + ++G + + V + +++
Sbjct: 1034 FLIVAVGVLLQPAGLG------TLRVLRVLRILSIFQGPRLVLGTLFQLVPAMFGGLLVI 1087
Query: 267 MFSLSVFALMGLQIYMG 283
+ VF+++G+ ++ G
Sbjct: 1088 LLVWLVFSVVGVNMFAG 1104
>UniRef50_Q4RQI5 Cluster: Chromosome 2 SCAF15004, whole genome shotgun
sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 2
SCAF15004, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1604
Score = 491 bits (1210), Expect = e-136
Identities = 238/443 (53%), Positives = 322/443 (72%), Gaps = 9/443 (2%)
Query: 1477 IDNFNEQKKKA-GGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTD 1535
+D+ ++ KKK ++FMTE+QKKYYNAMKK+GSKKP K IPRP + Q +F+ T
Sbjct: 1128 VDSQSKVKKKVIKCGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPSNKIQGYIFDFTTK 1187
Query: 1536 KKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYF 1595
+ FD+IIM+ I LNM+TM ++ +QSE L+Y+N++FIVIF+ ECLLK+ +LR++YF
Sbjct: 1188 QAFDIIIMVLIWLNMVTMMVETAEQSEKMKNTLNYINVVFIVIFTGECLLKMISLRHYYF 1247
Query: 1596 VEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLL 1655
WN+FDF+VV+ SI+ + LSDIIE YFVSPTL RV+R+A++GRVLRL+K AKGIRTLL
Sbjct: 1248 TYGWNIFDFIVVILSIIGVFLSDIIESYFVSPTLFRVIRLARIGRVLRLIKSAKGIRTLL 1307
Query: 1656 FALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQM 1715
FAL MSLPALFNI LLLFLVMFI+AIFGMS F +VK + G+DD++NF+TF SMI LFQ+
Sbjct: 1308 FALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKKESGIDDMFNFETFGNSMICLFQI 1367
Query: 1716 STSAGWDGVLDGII--NEEECDLPDNERGS--PGNCGSATIGITYLLSYLVISFLIVINM 1771
+TS GWD +L I+ NE +C GS G+CG+ T+GI + +SY++I FLIVINM
Sbjct: 1368 TTSGGWDTLLAPILNKNEPDCSNTTEHPGSSVKGDCGNPTVGIAFFVSYIIICFLIVINM 1427
Query: 1772 YIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQ 1831
YIAVILEN+ ATE+ + L++DD++M+YE+W++FDP +Q++ Y QLSDF D LEPPL
Sbjct: 1428 YIAVILENFGVATEESADPLSEDDFEMFYEVWEKFDPHATQFMEYRQLSDFADALEPPLC 1487
Query: 1832 IHKPNKYKIISMDIPICRGDMMFCVDILDALTKDFFARKGNPIEETGDLE----VGRPEE 1887
I KPNK ++ISMD+P+ G+ + C+DIL A TK G +E P +
Sbjct: 1488 IPKPNKIELISMDLPMVNGERIHCLDILFAFTKRVLGESGEMDILREQMEERFMASNPSK 1547
Query: 1888 AGYEPVSSTLWRQREEYCARLIQ 1910
YEP+++TL + E+ A IQ
Sbjct: 1548 VSYEPITTTLRHKLEDASAISIQ 1570
Score = 382 bits (941), Expect = e-104
Identities = 216/429 (50%), Positives = 275/429 (64%), Gaps = 49/429 (11%)
Query: 16 FRPFTRESLXXXXXXXXXXXXKQKELEKKRAEGEVRYXXXXXXXGPQPDATLEQGLPLPV 75
FRPF RESL ++ + EKK+ E +P + LE G LP+
Sbjct: 13 FRPFNRESLKAIEARIAEEKARKPKGEKKKHRKE---------NDLKPSSDLEAGKSLPL 63
Query: 76 RMQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNALWILDPFNPIRRVAI 135
+ P + S PLED+DP+Y+NQ TF+VI+KG IFRF+A AL++L PFNP+RR++I
Sbjct: 64 -LYRDVPKGMVSIPLEDLDPYYNNQKTFIVINKGSYIFRFNAAPALYLLSPFNPLRRISI 122
Query: 136 YILVH--PLFS--------LFIITTILVNCILMIMPTTPT-VESTEVIFTGIYTFESAVK 184
+L H PL L I+ TIL NC LM P ++ E FT IYTFES VK
Sbjct: 123 RVLTHSYPLNIHIGCTVNLLVIMCTILANCGLMTQDGPPEWAKNVEYTFTAIYTFESLVK 182
Query: 185 VMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPG 244
++ARGF L FT+LRD WNWLDF VI +AYVT ++LGN + LRT RVLRALK ++++PG
Sbjct: 183 ILARGFCLGKFTFLRDPWNWLDFSVIVMAYVTEFVNLGNFSVLRTLRVLRALKAISVIPG 242
Query: 245 LKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFP---------- 294
LKTIVGA+ +SVK L DV+ILT+F LSVFAL+GLQ++MG L KCV + P
Sbjct: 243 LKTIVGALFQSVKKLADVMILTVFCLSVFALIGLQLFMGHLKHKCV-LMPASSANSSANE 301
Query: 295 --EDGSWGNLTDE-NWERFCQNETN-WYGEGGDYP-LCGNSSGAGQCEPGYVCLQGFGPN 349
+G+ N +D NW F + N +Y G P LCGN SGAG C GY C++ G N
Sbjct: 302 TYANGTHLNQSDSFNWTEFSLDPKNHFYLPGKRDPLLCGNGSGAGPCPEGYSCIR-VGKN 360
Query: 350 PNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNL 398
P+YGYTSFD+FGWAFLS FRLMTQD WENLY+ +FFV++IFLGSFYL+NL
Sbjct: 361 PDYGYTSFDSFGWAFLSLFRLMTQDAWENLYRQTLRASGKPYMIFFVLVIFLGSFYLINL 420
Query: 399 ILAIVAMSY 407
ILA+VAM+Y
Sbjct: 421 ILAVVAMAY 429
Score = 296 bits (726), Expect = 5e-78
Identities = 144/269 (53%), Positives = 192/269 (71%), Gaps = 8/269 (2%)
Query: 1177 PADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALA 1236
P C P+ Q+F + + +W+ W TLR ++++E+++FE+ +I MILLSS ALA
Sbjct: 865 PDACFPDSWVQRFRCCQVNVEVGWWKIWWTLRKTCYQIVEHSWFESFIIFMILLSSGALA 924
Query: 1237 LEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSL 1296
ED+++ R ++ +L Y D+IFT IF +EML+KW+A GF KYFTNAWCWLDF+IV VSL
Sbjct: 925 CEDIYIEQRKTIKVLLEYADKIFTCIFILEMLLKWMAYGFAKYFTNAWCWLDFLIVDVSL 984
Query: 1297 INFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLI 1356
I+ +A G + A K++RTLRALRPLRA+SR +GMRVVVNAL+ AIPSIFNVLLVCLI
Sbjct: 985 ISLIANALGWSDLGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIFNVLLVCLI 1044
Query: 1357 FWLIFAIMGVQLFAGKYFKCVDMNHTT---LSHEIIPDKNACTLENY---TWENSPMNFD 1410
FWLIF+IMGV LFAGK++ C+ N TT ++ KN C + ++ W+N +NFD
Sbjct: 1045 FWLIFSIMGVNLFAGKFWVCI--NRTTDLPFPRTVVKTKNDCQIMSHDVALWKNLKVNFD 1102
Query: 1411 HVGKAYLCLFQVATFKGWIQIMNDAIDSR 1439
+VG YL L QVATFKGW IM A+DS+
Sbjct: 1103 NVGLGYLALLQVATFKGWTDIMYAAVDSQ 1131
Score = 78.2 bits (184), Expect = 2e-12
Identities = 60/224 (26%), Positives = 112/224 (50%), Gaps = 31/224 (13%)
Query: 1220 FETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKY 1279
F+ ++ +I L+ + + +E + +++ L Y++ +F VIF E L+K ++L Y
Sbjct: 1190 FDIIIMVLIWLNMVTMMVETAEQSEK--MKNTLNYINVVFIVIFTGECLLKMISLRHY-Y 1246
Query: 1280 FTNAWCWLDFIIVMVSLIN-FVAALCGAGGIQA--FKTMRTLRALRPLRAMSRMQGMRVV 1336
FT W DFI+V++S+I F++ + + + F+ +R R R LR + +G+R +
Sbjct: 1247 FTYGWNIFDFIVVILSIIGVFLSDIIESYFVSPTLFRVIRLARIGRVLRLIKSAKGIRTL 1306
Query: 1337 VNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACT 1396
+ AL+ ++P++FN+ L+ + I+AI G+ FA Y K I D
Sbjct: 1307 LFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFA--YVK---------KESGIDDM---- 1351
Query: 1397 LENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSRE 1440
NF+ G + +CLFQ+ T GW ++ ++ E
Sbjct: 1352 ----------FNFETFGNSMICLFQITTSGGWDTLLAPILNKNE 1385
Score = 77.4 bits (182), Expect = 4e-12
Identities = 47/127 (37%), Positives = 73/127 (57%), Gaps = 13/127 (10%)
Query: 1259 FTVIFFIEMLIKWLALGFQ----KYFTNAWCWLDF-IIVMVSLINFVAALCGAGGIQAFK 1313
FT I+ E L+K LA GF + + W WLDF +IVM + FV + F
Sbjct: 171 FTAIYTFESLVKILARGFCLGKFTFLRDPWNWLDFSVIVMAYVTEFV-------NLGNFS 223
Query: 1314 TMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
+RTLR LR L+A+S + G++ +V AL Q++ + +V+++ + +FA++G+QLF G
Sbjct: 224 VLRTLRVLRALKAISVIPGLKTIVGALFQSVKKLADVMILTVFCLSVFALIGLQLFMGHL 283
Query: 1374 -FKCVDM 1379
KCV M
Sbjct: 284 KHKCVLM 290
Score = 77.0 bits (181), Expect = 5e-12
Identities = 47/169 (27%), Positives = 92/169 (54%), Gaps = 19/169 (11%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVN-----CILMIMPTTPTV----ESTEVIFTGIYTFE 180
+R+ I+ H F FII IL++ C + + T+ E + IFT I+ E
Sbjct: 895 LRKTCYQIVEHSWFESFIIFMILLSSGALACEDIYIEQRKTIKVLLEYADKIFTCIFILE 954
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM------GIDLGNLAALRTFRVLR 234
+K MA GF Y +AW WLDF+++ ++ +++ DLG + +LRT R LR
Sbjct: 955 MLLKWMAYGFA----KYFTNAWCWLDFLIVDVSLISLIANALGWSDLGAIKSLRTLRALR 1010
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
L+ ++ G++ +V A++ ++ ++ +V+++ + +F++MG+ ++ G
Sbjct: 1011 PLRALSRFEGMRVVVNALLGAIPSIFNVLLVCLIFWLIFSIMGVNLFAG 1059
Score = 76.2 bits (179), Expect = 9e-12
Identities = 48/168 (28%), Positives = 87/168 (51%), Gaps = 6/168 (3%)
Query: 1523 WRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLD--HYQQSETFSAVLDYLNMIFIVIFS 1580
W + ++IV F+ I+ I L+ + + + +Q +T +L+Y + IF IF
Sbjct: 893 WTLRKTCYQIVEHSWFESFIIFMILLSSGALACEDIYIEQRKTIKVLLEYADKIFTCIFI 952
Query: 1581 SECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVG 1639
E LLK A + YF W DF++V S++SL+ + + + LR +R
Sbjct: 953 LEMLLKWMAYGFAKYFTNAWCWLDFLIVDVSLISLIANALGWSDLGAIKSLRTLRAL--- 1009
Query: 1640 RVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
R LR + +G+R ++ AL ++P++FN+ L+ + IF+I G++ F
Sbjct: 1010 RPLRALSRFEGMRVVVNALLGAIPSIFNVLLVCLIFWLIFSIMGVNLF 1057
Score = 54.4 bits (125), Expect = 3e-05
Identities = 37/125 (29%), Positives = 66/125 (52%), Gaps = 15/125 (12%)
Query: 1575 FIVIFSSECLLKIFAL-----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTL 1629
F I++ E L+KI A ++ + +PWN DF V+ V++ + E FV+
Sbjct: 171 FTAIYTFESLVKILARGFCLGKFTFLRDPWNWLDFSVI-------VMAYVTE--FVNLGN 221
Query: 1630 LRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM- 1688
V+R +V R L+ + G++T++ AL S+ L ++ +L + +FA+ G+ FM
Sbjct: 222 FSVLRTLRVLRALKAISVIPGLKTIVGALFQSVKKLADVMILTVFCLSVFALIGLQLFMG 281
Query: 1689 HVKDK 1693
H+K K
Sbjct: 282 HLKHK 286
Score = 44.8 bits (101), Expect = 0.024
Identities = 39/171 (22%), Positives = 79/171 (46%), Gaps = 25/171 (14%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTP-------TVESTEVIFTGIYT 178
P N I+ F + I+ I +N + M++ T T+ V+F I+T
Sbjct: 1173 PSNKIQGYIFDFTTKQAFDIIIMVLIWLNMVTMMVETAEQSEKMKNTLNYINVVFIVIFT 1232
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNL-----------AAL 227
E +K+++ FTY WN DF+V+ L+ + G+ L ++ +
Sbjct: 1233 GECLLKMISLRHYY--FTY---GWNIFDFIVVILSII--GVFLSDIIESYFVSPTLFRVI 1285
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGL 278
R R+ R L+ + G++T++ A++ S+ L ++ +L + ++A+ G+
Sbjct: 1286 RLARIGRVLRLIKSAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGM 1336
Score = 40.7 bits (91), Expect = 0.40
Identities = 32/146 (21%), Positives = 68/146 (46%), Gaps = 7/146 (4%)
Query: 776 DCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRV 835
+C + + Y ++ F + + L I+ L ++ + + + + ++ RV
Sbjct: 1234 ECLLKMISLRHYYFTYGWNIFDFIVVILSIIGVFLSDIIESYFVSPTLFRVIRLARIGRV 1293
Query: 836 FKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDG 895
+L KS + L+ + ++ AL N+ +L +++FI+A+ GM F YV + G
Sbjct: 1294 LRLIKSAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFA-----YVKK-ESG 1347
Query: 896 DLPRWNFTDFMHSFMIVFRV-LCGEW 920
+NF F +S + +F++ G W
Sbjct: 1348 IDDMFNFETFGNSMICLFQITTSGGW 1373
>UniRef50_A6N7F3 Cluster: Sodium channel protein; n=5; Coelomata|Rep:
Sodium channel protein - Ummeliata insecticeps
Length = 301
Score = 478 bits (1179), Expect = e-133
Identities = 225/302 (74%), Positives = 262/302 (86%), Gaps = 1/302 (0%)
Query: 1475 VIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVT 1534
VIIDNFNEQKKK GGSLEMFMTEDQKKYYNAMKKMG KKP+KAIPRPR++PQAIVF++ T
Sbjct: 1 VIIDNFNEQKKK-GGSLEMFMTEDQKKYYNAMKKMGDKKPVKAIPRPRFKPQAIVFDLTT 59
Query: 1535 DKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHY 1594
+ KFDM IMLFIGLNM+ M +D YQ E+F+A+LD LN+ FI IF++EC+LKIFA R+HY
Sbjct: 60 NTKFDMSIMLFIGLNMIVMAMDQYQIEESFNAILDRLNIFFIAIFTTECVLKIFAFRWHY 119
Query: 1595 FVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTL 1654
F EPWN+FDF+VV SIL +VL D+IEKYFVSPTLLRVVRV KVGRVLRLVKGA+GIRTL
Sbjct: 120 FKEPWNMFDFIVVSLSILGVVLKDLIEKYFVSPTLLRVVRVVKVGRVLRLVKGARGIRTL 179
Query: 1655 LFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQ 1714
LFALAMSLPALFNICLLLFLVMFI+A FGMSFF VK + G+D+ +NF+TF QSMILLF+
Sbjct: 180 LFALAMSLPALFNICLLLFLVMFIYATFGMSFFKTVKHRYGIDENFNFETFGQSMILLFE 239
Query: 1715 MSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIA 1774
MSTSAGWDGVL GI+ + +CD PD +PGNCGS I + L+SYL++SFLI+INMYIA
Sbjct: 240 MSTSAGWDGVLAGIMEDTDCDKPDEATDNPGNCGSRGIAVACLVSYLIVSFLIIINMYIA 299
Query: 1775 VI 1776
VI
Sbjct: 300 VI 301
Score = 67.3 bits (157), Expect = 4e-09
Identities = 54/220 (24%), Positives = 101/220 (45%), Gaps = 31/220 (14%)
Query: 1212 FKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKW 1271
F L NT F+ +++ I L+ + +A++ + IL ++ F IF E ++K
Sbjct: 55 FDLTTNTKFDMSIMLFIGLNMIVMAMDQYQIEES--FNAILDRLNIFFIAIFTTECVLKI 112
Query: 1272 LALGFQKYFTNAWCWLDFIIVMVSLINFVAA-LCGAGGIQA--FKTMRTLRALRPLRAMS 1328
A + YF W DFI+V +S++ V L + + +R ++ R LR +
Sbjct: 113 FAFRWH-YFKEPWNMFDFIVVSLSILGVVLKDLIEKYFVSPTLLRVVRVVKVGRVLRLVK 171
Query: 1329 RMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEI 1388
+G+R ++ AL ++P++FN+ L+ + I+A G+ F T+ H
Sbjct: 172 GARGIRTLLFALAMSLPALFNICLLLFLVMFIYATFGMSFF------------KTVKHRY 219
Query: 1389 IPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGW 1428
D+N NF+ G++ + LF+++T GW
Sbjct: 220 GIDEN-------------FNFETFGQSMILLFEMSTSAGW 246
Score = 45.2 bits (102), Expect = 0.018
Identities = 42/174 (24%), Positives = 80/174 (45%), Gaps = 22/174 (12%)
Query: 127 FNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVI-------FTGIYTF 179
F P + + + + F + I+ I +N I+M M ES I F I+T
Sbjct: 48 FKP-QAIVFDLTTNTKFDMSIMLFIGLNMIVMAMDQYQIEESFNAILDRLNIFFIAIFTT 106
Query: 180 ESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGN--------LAALRTF 230
E +K+ A + Y ++ WN DF+V++L+ + + + DL L +R
Sbjct: 107 ECVLKIFAFRW-----HYFKEPWNMFDFIVVSLSILGVVLKDLIEKYFVSPTLLRVVRVV 161
Query: 231 RVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
+V R L+ V G++T++ A+ S+ L ++ +L + ++A G+ + V
Sbjct: 162 KVGRVLRLVKGARGIRTLLFALAMSLPALFNICLLLFLVMFIYATFGMSFFKTV 215
>UniRef50_Q4S161 Cluster: Chromosome 13 SCAF14769, whole genome
shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
Chromosome 13 SCAF14769, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1557
Score = 442 bits (1089), Expect = e-122
Identities = 265/731 (36%), Positives = 408/731 (55%), Gaps = 85/731 (11%)
Query: 1219 YFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQK 1278
+F+ + +ILLSS ALA ED++L HR +L +L + +F ++FF+EML+KW+ GF+K
Sbjct: 844 FFKLFINVIILLSSTALACEDIYLQHRKVLMAVLAIAELVFALLFFMEMLLKWVGFGFRK 903
Query: 1279 YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVN 1338
YFT+AWCWL+F+IV V F+ +L G G ++ TLR LR +R +S +QG + VV
Sbjct: 904 YFTDAWCWLEFLIVGV----FLLSLVGVGSLE------TLRVLRVVRILSFLQGSQRVVG 953
Query: 1339 ALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH-EIIPDKNAC-- 1395
L + +PS+ + LV L+ WL+F+++GVQ+FAGK++ CV+ + H +++ +K+ C
Sbjct: 954 TLFRMVPSLVSGTLVILLVWLVFSVVGVQMFAGKFYYCVNETSGEMFHSDVVSNKSECFE 1013
Query: 1396 -TLENYT---WENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNI 1451
T NYT W N +N+D+V +L LF + K W I+ A+DS V QP+ E N
Sbjct: 1014 LTFSNYTEVRWVNPAINYDNVMMGFLSLFILGFSKSWFDIIYSAMDSSLVENQPVYENNP 1073
Query: 1452 YMYLYXXXXXXXXXXXTLNLFIGVIID------------NFNEQKKKAG---------GS 1490
Y++LY +LN FI V++ NF G S
Sbjct: 1074 YVWLY-FVFFFIAVFFSLNFFIKVLLTGLQKISLMFFQINFALMSLSFGLFLWYSPLCFS 1132
Query: 1491 LEMFMTEDQKKYYNAMKKMGSKKPLKAIP--------RPRWRPQAIVFEIVTDKKFDMII 1542
DQ+ + ++ S+ +K P RP+ + QA VF+++ +++++
Sbjct: 1133 FFQLYFGDQRLFMTQHQQKCSRALMKLFPRSPCRAVPRPQNKCQAGVFDVMNTSCYEIVM 1192
Query: 1543 MLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLF 1602
I LN+L + L+ +ET L ++ IFI+IF EC+ K+ A R HYF + WN+
Sbjct: 1193 AALICLNVLLLVLETVDTTETMYTALHWIYFIFIIIFLLECIFKLVAFRQHYFKDGWNIL 1252
Query: 1603 DFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSL 1662
DFVVV+ IL K++ P L +R+ +V RVL ++ + IR +L A S+
Sbjct: 1253 DFVVVLLQILG--------KFY--PDTLAFLRLFRVCRVLHVIPVTRRIRKVLLAFLKSV 1302
Query: 1663 PALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWD 1722
PALFNI +L +VM +F++ GM F +VK +DDV+NF+TF SMI LF STSAGW
Sbjct: 1303 PALFNIAFVLLVVMVVFSLIGMFNFAYVKKAALIDDVFNFETFCSSMICLFMTSTSAGWG 1362
Query: 1723 GVLDGIINE-EECDLPDNERGSP--GNCGSATIGITYLLSYLVISFLIVINMYIAVILEN 1779
+L +N +CD GS G+C + G+ + SY+++SFL++I +YI V++E
Sbjct: 1363 SLLRPFMNSPPDCDPFAEHPGSDVVGDCSTPIAGVAFFASYIILSFLLLIQLYITVVMEI 1422
Query: 1780 YSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHKPNKYK 1839
+ +ED E L DDD + + W FDPD +Q I Y +LS+F D L+ PL+I KPN +
Sbjct: 1423 IN--SEDT-ETLCDDDLQNFCKTWMTFDPDDTQLIPYSKLSEFSDSLQDPLRIPKPNATR 1479
Query: 1840 IISMDIPICRGDMMFCVDILDALTKDFFARKGNPIEETGDLEVGRPEEAGYEPVSSTLWR 1899
++ MD+P+ GD + C D+ AL K P+ EPVSSTL R
Sbjct: 1480 LVHMDLPLYPGDKVHCTDVFLALAKQV------------------PD----EPVSSTLRR 1517
Query: 1900 QREEYCARLIQ 1910
++E+ A++IQ
Sbjct: 1518 KQEDTAAKVIQ 1528
Score = 231 bits (566), Expect = 1e-58
Identities = 158/425 (37%), Positives = 224/425 (52%), Gaps = 47/425 (11%)
Query: 14 SLFRPFTRESLXXXXXXXXXXXXKQKELEKKRAEGEVRYXXXXXXXGPQPDATLEQGLPL 73
SL P E L ++KE EKK+ +G+ + P+P LE+G PL
Sbjct: 1 SLLPPVGTEFLRPFTSASLEQMSQRKEEEKKQ-KGKKKDQKVKNNELPKPSEDLEEGKPL 59
Query: 74 PVRMQGSFPLELASTPLEDIDPFYHNQTTFVVISKGKDIFRFSATNALWILDPFNPIRRV 133
P P L +TPLE++DP H TF+V+ KGK I RF+A A + P NP+R +
Sbjct: 60 PFIFGEPSPAHL-NTPLEELDP--HQSETFLVLGKGKLIHRFNAHKACCLFGPLNPLRTL 116
Query: 134 AIYILVHPLFSLF----IITTILVNCILMIMPTTPTVES--TEVIFTGIYTFESAVKVMA 187
AI IL + +F I TIL+N +L ++ T S E+ FT +Y E VK+++
Sbjct: 117 AIKILTNSYLLVFLCSLIFVTILINFVLTVVSTDFYAMSKIVELSFTAVYLLEVVVKIVS 176
Query: 188 RGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKT 247
RGF FT+LR+ WNW D VIA A++ + +D L V LKT I GLK
Sbjct: 177 RGFCWGKFTFLRNPWNWPDVGVIAGAFLLLFVDFPELKM-----VSLVLKTFPIFQGLKK 231
Query: 248 IVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLT---- 303
+ + ++++K L V+ LT F L + +++G ++ G L QKC+ +PE NLT
Sbjct: 232 TLSSFVQAMKRLSCVLALTAFMLCILSIIGQLLFQGSLRQKCIS-WPEADH--NLTSHSF 288
Query: 304 ----------DENWERFCQN-ETNWYGEGG--DYPLCGNSSGAGQCEPGYVCLQGFGPNP 350
D N+ N T Y G D +CGN+S AG C G+ CL+ NP
Sbjct: 289 ISHYDDDQSSDFNYYEHVNNPSTTHYIPSGMTDALVCGNTSNAGACPTGFTCLRN-QKNP 347
Query: 351 NYGYTSFDTFGWAFLSAFRLMTQDYWENLYQLF--------FVVIIFLGS---FYLVNLI 399
NYGYTSFD+FGWA LS+FRL+TQ YW++L +L F+ +FL S F LV+L+
Sbjct: 348 NYGYTSFDSFGWALLSSFRLLTQAYWDDLMRLVLRANGKTSFIYFLFLLSPCWFVLVSLM 407
Query: 400 LAIVA 404
A++A
Sbjct: 408 AAVMA 412
Score = 70.1 bits (164), Expect = 6e-10
Identities = 33/85 (38%), Positives = 48/85 (56%), Gaps = 2/85 (2%)
Query: 863 TFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP-DGDLPRWNFTDFMHSFMIVFRVLCGEWI 921
+F+L I+ F F +G QLF Y+ V + D LPRWN F +F +F++L W+
Sbjct: 629 SFLLLIVFFGFVAVGYQLFNMPYMVSVCKISEDCSLPRWNMNSFFQTFNSIFKMLFDSWV 688
Query: 922 ESMWDCMLVGD-VSCIPFFLATVVI 945
E +WDCM V C+ F ++ VVI
Sbjct: 689 EILWDCMEVASPAMCLTFVVSVVVI 713
Score = 69.3 bits (162), Expect = 1e-09
Identities = 65/264 (24%), Positives = 131/264 (49%), Gaps = 33/264 (12%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL- 1590
IVT+ FD+ I++ + +N++ +++H+ + F+ L +IFI I+ E LLKI A+
Sbjct: 503 IVTNPFFDLAIVVCLIINIIFTSMEHFPMTYEFAETLIVAELIFIFIYIGEMLLKILAMD 562
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEK-YFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
Y+YF WN+++ ++V+ S+ +VL+++ VS TL ++V + A+
Sbjct: 563 PYNYFKVGWNVYESLIVVLSLFEMVLAEVHGLCILVSVTLSWCIQVLLL---------AR 613
Query: 1650 GIRTLLFALAMSLPALFNICLLLF-LVMFIFAIFGMSFFMHV---KDKGGLDDVYNFKTF 1705
L +L F + ++ F V + +F M + + V + L +N +F
Sbjct: 614 WWHEFHVFLKTTLKYSFLLLIVFFGFVAVGYQLFNMPYMVSVCKISEDCSLPR-WNMNSF 672
Query: 1706 VQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISF 1765
Q+ +F+M + W +L +C E SP C +T+++S +VI
Sbjct: 673 FQTFNSIFKMLFDS-WVEIL------WDC----MEVASPAMC------LTFVVSVVVIGN 715
Query: 1766 LIVINMYIAVILENYSQATEDVQE 1789
L+++++++ ++L YS ++E
Sbjct: 716 LLILHLFLLMLLNPYSSDIVALEE 739
Score = 68.5 bits (160), Expect = 2e-09
Identities = 42/159 (26%), Positives = 83/159 (52%), Gaps = 10/159 (6%)
Query: 1212 FKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKW 1271
F ++ + +E + +I L+ L L LE V + L+++ IF +IF +E + K
Sbjct: 1180 FDVMNTSCYEIVMAALICLNVLLLVLETVDTTET--MYTALHWIYFIFIIIFLLECIFKL 1237
Query: 1272 LALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQ 1331
+A Q YF + W LDF++V++ ++ G +R R R L + +
Sbjct: 1238 VAFR-QHYFKDGWNILDFVVVLLQIL-------GKFYPDTLAFLRLFRVCRVLHVIPVTR 1289
Query: 1332 GMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
+R V+ A ++++P++FN+ V L+ ++F+++G+ FA
Sbjct: 1290 RIRKVLLAFLKSVPALFNIAFVLLVVMVVFSLIGMFNFA 1328
Score = 60.9 bits (141), Expect = 3e-07
Identities = 38/138 (27%), Positives = 69/138 (50%), Gaps = 3/138 (2%)
Query: 143 FSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFT--YLRD 200
+ + + I +N +L+++ T T E+ IY + ++ F L F Y +D
Sbjct: 1188 YEIVMAALICLNVLLLVLETVDTTETMYTALHWIYFIFIIIFLLECIFKLVAFRQHYFKD 1247
Query: 201 AWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLR 260
WN LDFVV+ L + LA LR FRV R L + + ++ ++ A ++SV L
Sbjct: 1248 GWNILDFVVVLLQILGKFYP-DTLAFLRLFRVCRVLHVIPVTRRIRKVLLAFLKSVPALF 1306
Query: 261 DVIILTMFSLSVFALMGL 278
++ + + + VF+L+G+
Sbjct: 1307 NIAFVLLVVMVVFSLIGM 1324
Score = 58.4 bits (135), Expect = 2e-06
Identities = 61/223 (27%), Positives = 103/223 (46%), Gaps = 29/223 (13%)
Query: 1479 NFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRW-RPQA---------- 1527
N E+KKK SL M T D+ K ++ G + A+P W RP+
Sbjct: 777 NGQEKKKKDYVSLNM-ATSDEAKV-RTPEEEGPEAATAAVPSWTWTRPRGPGGVASAAGR 834
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTLD--HYQQSETFSAVLDYLNMIFIVIFSSECLL 1585
V K F + I + I L+ + + + Q + AVL ++F ++F E LL
Sbjct: 835 SVSSSFRTKFFKLFINVIILLSSTALACEDIYLQHRKVLMAVLAIAELVFALLFFMEMLL 894
Query: 1586 KIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRL 1644
K + YF + W +F++V +LSLV +E LRV+RV R+L
Sbjct: 895 KWVGFGFRKYFTDAWCWLEFLIVGVFLLSLVGVGSLE-------TLRVLRVV---RILSF 944
Query: 1645 VKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
++G++ + LF + +P+L + L++ LV +F++ G+ F
Sbjct: 945 LQGSQRVVGTLFRM---VPSLVSGTLVILLVWLVFSVVGVQMF 984
Score = 56.4 bits (130), Expect = 7e-06
Identities = 30/114 (26%), Positives = 65/114 (57%), Gaps = 8/114 (7%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRT 229
E++F ++ E +K + GF Y DAW WL+F+++ + +++ + +G+L T
Sbjct: 881 ELVFALLFFMEMLLKWVGFGFR----KYFTDAWCWLEFLIVGVFLLSL-VGVGSL---ET 932
Query: 230 FRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
RVLR ++ ++ + G + +VG + V +L ++ + VF+++G+Q++ G
Sbjct: 933 LRVLRVVRILSFLQGSQRVVGTLFRMVPSLVSGTLVILLVWLVFSVVGVQMFAG 986
Score = 50.8 bits (116), Expect = 4e-04
Identities = 22/89 (24%), Positives = 42/89 (47%), Gaps = 1/89 (1%)
Query: 749 EDDEDGPTFKE-KLLDCLMKGIDFFCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVV 807
E E PT K C W+CC W ++++ +V +PF +L I +C+++
Sbjct: 460 ESQEPQPTSKGVSCCPCCSACAKLLLTWNCCGCWRWLKRWLHTIVTNPFFDLAIVVCLII 519
Query: 808 NTLFMALDHHNMDKDMDKALKSGNYLRVF 836
N +F +++H M + + L + +F
Sbjct: 520 NIIFTSMEHFPMTYEFAETLIVAELIFIF 548
Score = 49.2 bits (112), Expect = 0.001
Identities = 27/99 (27%), Positives = 50/99 (50%), Gaps = 2/99 (2%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W L+ ++ N +F+ A++ ++++ + ++E H P + L + IF I+
Sbjct: 493 WRWLKRWLHTIVTNPFFDLAIVVCLIINIIFTSME--HFPMTYEFAETLIVAELIFIFIY 550
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAA 1302
EML+K LA+ YF W + +IV++SL V A
Sbjct: 551 IGEMLLKILAMDPYNYFKVGWNVYESLIVVLSLFEMVLA 589
Score = 41.1 bits (92), Expect = 0.30
Identities = 48/218 (22%), Positives = 93/218 (42%), Gaps = 27/218 (12%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
LR K++ N+Y + ++I ++ L + V + I+ + FT ++ +E
Sbjct: 113 LRTLAIKILTNSYLLVFLCSLIFVTILINFVLTVVSTDFYAMSKIV---ELSFTAVYLLE 169
Query: 1267 MLIKWLALGFQ----KYFTNAWCWLDF-IIVMVSLINFVAALCGAGGIQAFKTMRTLRAL 1321
+++K ++ GF + N W W D +I L+ FV F ++ + +
Sbjct: 170 VVVKIVSRGFCWGKFTFLRNPWNWPDVGVIAGAFLLLFVD----------FPELKMVSLV 219
Query: 1322 RPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKCV--- 1377
L+ QG++ +++ VQA+ + VL + I +I+G LF G KC+
Sbjct: 220 --LKTFPIFQGLKKTLSSFVQAMKRLSCVLALTAFMLCILSIIGQLLFQGSLRQKCISWP 277
Query: 1378 DMNHTTLSHEII---PDKNACTLENYTWENSPMNFDHV 1412
+ +H SH I D + Y N+P ++
Sbjct: 278 EADHNLTSHSFISHYDDDQSSDFNYYEHVNNPSTTHYI 315
Score = 40.3 bits (90), Expect = 0.52
Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 11/88 (12%)
Query: 137 ILVHPLFSLFIITTILVNCILMIMPTTP-------TVESTEVIFTGIYTFESAVKVMARG 189
I+ +P F L I+ +++N I M P T+ E+IF IY E +K++A
Sbjct: 503 IVTNPFFDLAIVVCLIINIIFTSMEHFPMTYEFAETLIVAELIFIFIYIGEMLLKILA-- 560
Query: 190 FILQPFTYLRDAWNWLDFVVIALAYVTM 217
+ P+ Y + WN + +++ L+ M
Sbjct: 561 --MDPYNYFKVGWNVYESLIVVLSLFEM 586
>UniRef50_UPI000069E3BF Cluster: Sodium channel protein type 4
subunit alpha (Sodium channel protein type IV subunit
alpha) (Voltage-gated sodium channel subunit alpha
Nav1.4) (Sodium channel protein, skeletal muscle subunit
alpha) (SkM1).; n=1; Xenopus tropicalis|Rep: Sodium
channel protein type 4 subunit alpha (Sodium channel
protein type IV subunit alpha) (Voltage-gated sodium
channel subunit alpha Nav1.4) (Sodium channel protein,
skeletal muscle subunit alpha) (SkM1). - Xenopus
tropicalis
Length = 774
Score = 411 bits (1013), Expect = e-113
Identities = 222/410 (54%), Positives = 281/410 (68%), Gaps = 32/410 (7%)
Query: 17 RPFTRESLXXXXXXXXXXXXKQKELEKKRAEGEVRYXXXXXXXGPQPDATLEQGLPLPVR 76
RPFTRESL ++++ +K + EV P P LE G LP+
Sbjct: 11 RPFTRESLAAIEKRI------EEDIARKAKQIEV-----LDEKVPTPKNGLEAGKNLPL- 58
Query: 77 MQGSFPLELASTPLEDIDPFYHNQT-TFVVISKGKDIFRFSATNALWILDPFNPIRRVAI 135
+ G P EL P+E++D FY NQ TF+V++KGK IFRF+AT AL++LDPFNPIRR AI
Sbjct: 59 IYGDPPPELIGIPIEELDSFYSNQKQTFIVLNKGKAIFRFTATKALYLLDPFNPIRRGAI 118
Query: 136 YILVH--PL-FSLFIITTILVNCILMIMPTTPT-VESTEVIFTGIYTFESAVKVMARGFI 191
+L+H PL FSLFI+ TIL NC+ M M P ++ E FTGIYTFES +K++ARGF
Sbjct: 119 KVLIHSYPLMFSLFIMFTILTNCVFMTMSDPPPWSKNVEYTFTGIYTFESLIKILARGFC 178
Query: 192 LQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGA 251
+ FT+LRD WNWLDF VI +AY T +DLGN++ALRTFRVLRALKT+ ++PGLKTIVGA
Sbjct: 179 IDSFTFLRDPWNWLDFCVIVMAYTTEFVDLGNVSALRTFRVLRALKTITVIPGLKTIVGA 238
Query: 252 VIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFC 311
+I+SVK L DV+ILT+F L+VFAL+GLQ++MG L KCV+ P D + +
Sbjct: 239 LIQSVKKLADVMILTLFCLAVFALIGLQLFMGNLRHKCVRWPPPDDYFMLYDNSTLNSTL 298
Query: 312 QNE-TNWYGEGG--DYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAF 368
N+ TN+Y G D LCGNSS AG+C Y C++ G NPNYGYTS+D+F WAFLS F
Sbjct: 299 YNDTTNFYFLDGANDALLCGNSSDAGKCPESYTCMK-TGRNPNYGYTSYDSFNWAFLSLF 357
Query: 369 RLMTQDYWENLYQL-----------FFVVIIFLGSFYLVNLILAIVAMSY 407
RLMTQD+WENL+QL FFVV+IFLGSFYL+NLILA+VAM+Y
Sbjct: 358 RLMTQDFWENLFQLTLRAAGKTYMVFFVVVIFLGSFYLINLILAVVAMAY 407
Score = 172 bits (419), Expect = 7e-41
Identities = 84/169 (49%), Positives = 108/169 (63%), Gaps = 2/169 (1%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+S LRVFKLAKSWPTLN+LI I+G ++GALGNLT VL II+FIFAV+GMQLFGK+Y
Sbjct: 606 LRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYK 665
Query: 887 DYVDRF-PDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCM-LVGDVSCIPFFLATVV 944
+ V + D +LPRW+ DF HSF+IVFR+LCGEWIE+MWDCM + G C+ F+ +V
Sbjct: 666 ECVCKIASDCELPRWHMHDFFHSFLIVFRILCGEWIETMWDCMEVAGQAMCLVVFMMVMV 725
Query: 945 IXXXXXXXXXXXXXXXXXXXXXXXTPTADQDTNKIAEAFNRISRFIDWI 993
I D + N + A RI+R ID++
Sbjct: 726 IGNLVVLNLFLALLLSSFSADNLSASDDDGEMNNLQIAIGRITRGIDFV 774
Score = 96.7 bits (230), Expect = 6e-18
Identities = 56/157 (35%), Positives = 90/157 (57%), Gaps = 9/157 (5%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL- 1590
+V D D+ I + I LN L M ++HY +E F VL+ N++F IF++E KI AL
Sbjct: 512 VVMDPFVDLGITICIVLNTLFMAMEHYPMTEQFEGVLNVGNLVFTGIFAAEMFFKIIALD 571
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
Y+YF WN+FD ++V S++ L L+++ L V+R ++ RV +L K
Sbjct: 572 PYYYFQVGWNIFDSIIVTLSLVELGLANV--------EGLSVLRSFRLLRVFKLAKSWPT 623
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+ L+ + S+ AL N+ L+L +++FIFA+ GM F
Sbjct: 624 LNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLF 660
Score = 81.0 bits (191), Expect = 3e-13
Identities = 31/60 (51%), Positives = 46/60 (76%)
Query: 772 FCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGN 831
F +WDCC LW++F+++V +V DPFV+L IT+CIV+NTLFMA++H+ M + + L GN
Sbjct: 493 FLIWDCCDLWVKFKEFVRFVVMDPFVDLGITICIVLNTLFMAMEHYPMTEQFEGVLNVGN 552
Score = 80.6 bits (190), Expect = 4e-13
Identities = 50/187 (26%), Positives = 97/187 (51%), Gaps = 14/187 (7%)
Query: 113 FRFSATNALW-ILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTE- 170
++F+ T +W D + + ++++ P L I I++N + M M P E E
Sbjct: 487 YKFANTFLIWDCCDLWVKFKEFVRFVVMDPFVDLGITICIVLNTLFMAMEHYPMTEQFEG 546
Query: 171 ------VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGN 223
++FTGI+ E K++A L P+ Y + WN D +++ L+ V +G+ ++
Sbjct: 547 VLNVGNLVFTGIFAAEMFFKIIA----LDPYYYFQVGWNIFDSIIVTLSLVELGLANVEG 602
Query: 224 LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
L+ LR+FR+LR K P L ++ + SV L ++ ++ + +FA++G+Q++ G
Sbjct: 603 LSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLF-G 661
Query: 284 VLTQKCV 290
++CV
Sbjct: 662 KSYKECV 668
Score = 76.6 bits (180), Expect = 7e-12
Identities = 45/164 (27%), Positives = 82/164 (50%), Gaps = 7/164 (4%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
++ + + + + I+L++L +A+E H P + +L + +FT IF EM K +A
Sbjct: 512 VVMDPFVDLGITICIVLNTLFMAME--HYPMTEQFEGVLNVGNLVFTGIFAAEMFFKIIA 569
Query: 1274 LGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGM 1333
L YF W D IIV +SL+ G ++ +R+ R LR + +
Sbjct: 570 LDPYYYFQVGWNIFDSIIVTLSLVEL-----GLANVEGLSVLRSFRLLRVFKLAKSWPTL 624
Query: 1334 RVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCV 1377
+++ + ++ ++ N+ LV I IFA++G+QLF Y +CV
Sbjct: 625 NMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECV 668
Score = 74.1 bits (174), Expect = 3e-11
Identities = 41/124 (33%), Positives = 70/124 (56%), Gaps = 11/124 (8%)
Query: 1259 FTVIFFIEMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKT 1314
FT I+ E LIK LA GF + + W WLDF +++++ + G + A +T
Sbjct: 160 FTGIYTFESLIKILARGFCIDSFTFLRDPWNWLDFCVIVMA---YTTEFVDLGNVSALRT 216
Query: 1315 MRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY- 1373
R LRAL+ + + G++ +V AL+Q++ + +V+++ L +FA++G+QLF G
Sbjct: 217 FRVLRALKTITV---IPGLKTIVGALIQSVKKLADVMILTLFCLAVFALIGLQLFMGNLR 273
Query: 1374 FKCV 1377
KCV
Sbjct: 274 HKCV 277
Score = 50.0 bits (114), Expect = 6e-04
Identities = 40/156 (25%), Positives = 73/156 (46%), Gaps = 20/156 (12%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL-----RY 1592
F + IM I N + MT+ +S ++Y F I++ E L+KI A +
Sbjct: 129 FSLFIMFTILTNCVFMTMS---DPPPWSKNVEYT---FTGIYTFESLIKILARGFCIDSF 182
Query: 1593 HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIR 1652
+ +PWN DF V++ + + FV + +R +V R L+ + G++
Sbjct: 183 TFLRDPWNWLDFCVIVMAYTT---------EFVDLGNVSALRTFRVLRALKTITVIPGLK 233
Query: 1653 TLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
T++ AL S+ L ++ +L + +FA+ G+ FM
Sbjct: 234 TIVGALIQSVKKLADVMILTLFCLAVFALIGLQLFM 269
>UniRef50_Q4S1P9 Cluster: Chromosome 11 SCAF14767, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 11 SCAF14767, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1180
Score = 344 bits (846), Expect = 1e-92
Identities = 209/437 (47%), Positives = 266/437 (60%), Gaps = 57/437 (13%)
Query: 16 FRPFTRESLXXXXXXXXXXXXKQKELEKKRAEGEVRYXXXXXXXGPQPDATLEQGLPLPV 75
F+ FT ESL K K+ K R++ R P D LE G LP
Sbjct: 14 FKKFTPESLANIEKRIQEE--KNKKPPKPRSDSSHRDTSDENEEKPNSD--LEAGKSLPF 69
Query: 76 RMQGSFPLELASTPLEDIDPFYHN---------QTTFVVISKGKDIFRFSATN-----AL 121
+ G P + +TPLED+DP+Y N Q T S ++ S N A+
Sbjct: 70 -IYGDAPAGMIATPLEDLDPYYMNKKTFIVLNKQKTIFRFSATPSLYILSPFNLLRRIAI 128
Query: 122 WILDPFNPIR-------------RVAIYIL---VHPLFSLFIITTILVNCILMIMPTTPT 165
IL P + R+A L + LFS+ I+ TIL NCI M P
Sbjct: 129 KILIHSYPFKCFTFSVLYDCYLGRIAHLFLNSGLLTLFSMIIMCTILTNCIFMTFSDPPE 188
Query: 166 -VESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNL 224
+ E FTGIYTFES K++ARGF + FT+LRDAWNWLDF+VI++AY+T +DLGN+
Sbjct: 189 WSKQVEYTFTGIYTFESLTKIVARGFAIDDFTFLRDAWNWLDFMVISMAYITEFVDLGNV 248
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
+ALRTFRVLRALKT++++PGLKTIVGA+I+SVK L DV+ILT+F LSVFAL+GLQ++MG
Sbjct: 249 SALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGN 308
Query: 285 LTQKCVKVFPEDGSWGNLT-DENWERFCQNETNWYGEGG--DYPLCGNSSGAGQCEPGYV 341
L KCV ++P N+T D +W F NE+N+Y G D LCGNSS +GQC GY
Sbjct: 309 LRNKCV-IWPV-----NMTNDFDWGEFIMNESNFYFLHGQSDALLCGNSSDSGQCPEGYK 362
Query: 342 CLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENL-----------YQLFFVVIIFL 390
C++ G NPNYGYTSFD+FGWAFL+ FRLMTQD WE L Y +FFV++IF+
Sbjct: 363 CMKA-GRNPNYGYTSFDSFGWAFLTLFRLMTQDAWEALYMQTLRAAGKTYMIFFVLVIFV 421
Query: 391 GSFYLVNLILAIVAMSY 407
GSFYLVNLILA+VAM+Y
Sbjct: 422 GSFYLVNLILAVVAMAY 438
Score = 123 bits (297), Expect = 4e-26
Identities = 64/147 (43%), Positives = 92/147 (62%), Gaps = 9/147 (6%)
Query: 1159 LGKTDIKVGADEDVVDDTPADCCPE-QCYQKFPFLAGDDDSPFWQGWGT----LRLKTFK 1213
+G++D++ ED ++ + + +C K+ D P GWG LR +
Sbjct: 1019 VGESDLENLNTEDFSSESDVENSKDVKCVAKYKCC----DVPITHGWGKHWWYLRKTCYL 1074
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
++E+ +FET +I MILLSS ALA EDV++ R ++ IL Y DR+FT IF +EML+KW+A
Sbjct: 1075 IVEHNWFETLIIFMILLSSGALAFEDVYIEQRKTVRIILEYADRVFTYIFILEMLLKWVA 1134
Query: 1274 LGFQKYFTNAWCWLDFIIVMVSLINFV 1300
GF KYFTNAWCWLDF IV VS ++ +
Sbjct: 1135 YGFVKYFTNAWCWLDFFIVDVSALHLL 1161
Score = 85.0 bits (201), Expect = 2e-14
Identities = 56/163 (34%), Positives = 90/163 (55%), Gaps = 12/163 (7%)
Query: 1521 PRW-RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIF 1579
P W + + IV+ IV D D+ I + I LN L M ++HY + F+ VL N++F IF
Sbjct: 763 PLWLKIKHIVYLIVMDPFVDLAITICIVLNTLFMAMEHYPMTPHFTDVLATGNLVFTGIF 822
Query: 1580 SSECLLKIFAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKV 1638
+ E K+ A+ Y+YF E WN FD +V S++ L L+++ ++LR RV
Sbjct: 823 AGEMFAKLIAMDPYYYFQEGWNCFDGFIVTLSLVELGLANV-----EGLSVLRSFRV--- 874
Query: 1639 GRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAI 1681
V +L K + L+ + S+ AL N+ L+L +++FIFA+
Sbjct: 875 --VFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAV 915
Score = 79.0 bits (186), Expect = 1e-12
Identities = 34/74 (45%), Positives = 48/74 (64%)
Query: 758 KEKLLDCLMKGIDFFCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHH 817
+ K C K + F +W+CC LWL+ + V L+V DPFV+L IT+CIV+NTLFMA++H+
Sbjct: 742 QRKCPPCWYKFSNTFLIWECCPLWLKIKHIVYLIVMDPFVDLAITICIVLNTLFMAMEHY 801
Query: 818 NMDKDMDKALKSGN 831
M L +GN
Sbjct: 802 PMTPHFTDVLATGN 815
Score = 73.3 bits (172), Expect = 6e-11
Identities = 40/124 (32%), Positives = 72/124 (58%), Gaps = 11/124 (8%)
Query: 1259 FTVIFFIEMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKT 1314
FT I+ E L K +A GF + +AW WLDF+++ ++ ++ G + A +T
Sbjct: 197 FTGIYTFESLTKIVARGFAIDDFTFLRDAWNWLDFMVISMA---YITEFVDLGNVSALRT 253
Query: 1315 MRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY- 1373
R LRAL+ + S + G++ +V AL+Q++ + +V+++ + +FA++G+QLF G
Sbjct: 254 FRVLRALKTI---SVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLR 310
Query: 1374 FKCV 1377
KCV
Sbjct: 311 NKCV 314
Score = 71.7 bits (168), Expect = 2e-10
Identities = 34/47 (72%), Positives = 41/47 (87%), Gaps = 1/47 (2%)
Query: 835 VFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
VFKLAKSWPTLN+LI I+G ++GALGNLT VL II+FIFAV+ + LF
Sbjct: 875 VFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVV-LNLF 920
Score = 69.7 bits (163), Expect = 7e-10
Identities = 47/178 (26%), Positives = 94/178 (52%), Gaps = 8/178 (4%)
Query: 113 FRFSATNALWILDP-FNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTP-TVESTE 170
++FS T +W P + I+ + I++ P L I I++N + M M P T T+
Sbjct: 750 YKFSNTFLIWECCPLWLKIKHIVYLIVMDPFVDLAITICIVLNTLFMAMEHYPMTPHFTD 809
Query: 171 VIFTG--IYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGNLAAL 227
V+ TG ++T A ++ A+ + P+ Y ++ WN D ++ L+ V +G+ ++ L+ L
Sbjct: 810 VLATGNLVFTGIFAGEMFAKLIAMDPYYYFQEGWNCFDGFIVTLSLVELGLANVEGLSVL 869
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVL 285
R+FRV+ K P L ++ + SV L ++ ++ + +FA++ L +++ +L
Sbjct: 870 RSFRVV--FKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVV-LNLFLALL 924
Score = 60.1 bits (139), Expect = 6e-07
Identities = 38/161 (23%), Positives = 77/161 (47%), Gaps = 9/161 (5%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W ++ + ++ + + + A+ I+L++L +A+E H P P D+L + +FT IF
Sbjct: 765 WLKIKHIVYLIVMDPFVDLAITICIVLNTLFMAME--HYPMTPHFTDVLATGNLVFTGIF 822
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRP 1323
EM K +A+ YF W D IV +SL+ G ++ +R+ R +
Sbjct: 823 AGEMFAKLIAMDPYYYFQEGWNCFDGFIVTLSLVEL-----GLANVEGLSVLRSFRVV-- 875
Query: 1324 LRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIM 1364
+ + +++ + ++ ++ N+ LV I IFA++
Sbjct: 876 FKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVV 916
Score = 50.4 bits (115), Expect = 5e-04
Identities = 43/156 (27%), Positives = 75/156 (48%), Gaps = 20/156 (12%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKI----FALRYH 1593
F MIIM I N + MT + +S ++Y F I++ E L KI FA+
Sbjct: 166 FSMIIMCTILTNCIFMT---FSDPPEWSKQVEYT---FTGIYTFESLTKIVARGFAIDDF 219
Query: 1594 YFV-EPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIR 1652
F+ + WN DF+V+ + ++ FV + +R +V R L+ + G++
Sbjct: 220 TFLRDAWNWLDFMVISMAYIT---------EFVDLGNVSALRTFRVLRALKTISVIPGLK 270
Query: 1653 TLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
T++ AL S+ L ++ +L + +FA+ G+ FM
Sbjct: 271 TIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFM 306
Score = 44.8 bits (101), Expect = 0.024
Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 3/99 (3%)
Query: 1523 WRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLD--HYQQSETFSAVLDYLNMIFIVIFS 1580
W + + IV F+ +I+ I L+ + + + +Q +T +L+Y + +F IF
Sbjct: 1066 WYLRKTCYLIVEHNWFETLIIFMILLSSGALAFEDVYIEQRKTVRIILEYADRVFTYIFI 1125
Query: 1581 SECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSLVLSD 1618
E LLK A + YF W DF +V S L L+ D
Sbjct: 1126 LEMLLKWVAYGFVKYFTNAWCWLDFFIVDVSALHLLKCD 1164
>UniRef50_A5YW88 Cluster: Voltage-gated calcium channel alpha 1
subunit; n=4; Coelomata|Rep: Voltage-gated calcium
channel alpha 1 subunit - Anopheles gambiae (African
malaria mosquito)
Length = 1893
Score = 331 bits (814), Expect = 1e-88
Identities = 210/662 (31%), Positives = 353/662 (53%), Gaps = 42/662 (6%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
L ++ F ++ I+ SS LA ED L IL Y D FT +F IE+L+K ++
Sbjct: 852 LCNHSTFGNIILVCIMFSSAMLAAEDP-LNANSERNQILNYFDYFFTSVFTIELLLKLVS 910
Query: 1274 LGFQKYFTNAWC-----WLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMS 1328
GF + A+C LD ++V VSLI+ + +G I K +R LR LRPLRA++
Sbjct: 911 YGFL-FHDGAFCRSAFNLLDLLVVCVSLISMFFS---SGAISVIKILRVLRVLRPLRAIN 966
Query: 1329 RMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD---MNHTTL- 1384
R +G++ VV ++ A+ +I N++LV + +FA++GVQL+ GK+F C D M +
Sbjct: 967 RAKGLKHVVQCVIVAVKTIGNIVLVTCLLQFMFAVIGVQLYKGKFFSCSDGSKMQESECH 1026
Query: 1385 -SHEIIPDKNA---CTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSRE 1440
++ + D N + E Y W + +FD V KA L LF V+TF+GW ++ +IDS E
Sbjct: 1027 GTYLVYEDGNVDKPVSKERY-WSRNRFHFDDVSKAMLTLFTVSTFEGWPGLLYVSIDSHE 1085
Query: 1441 VGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQK 1500
PI + Y +N+F+G +I F + G E + K
Sbjct: 1086 EDSGPIHNFRPIVAAYYIIYIIIIAFFMVNIFVGFVIVTFQNE-----GEQEYKNCDLDK 1140
Query: 1501 KYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQ 1560
N ++ KP++ P+ R Q V+ VT + F+ +I + I +N +T+++ Y+Q
Sbjct: 1141 NQRNCIEFALKAKPIRRY-IPKHRIQYKVWWFVTSQPFEYMIFVLIMINTITLSMKFYRQ 1199
Query: 1561 SETFSAVLDYLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSLVLSDI 1619
E ++ VLD LN+IF +F+ E + K+ A R+ +YF + WN+FDF++V+ S + +V S++
Sbjct: 1200 PEIYTEVLDLLNLIFTAVFALEFVFKLAAFRFKNYFGDAWNVFDFIIVLGSFIDIVYSEV 1259
Query: 1620 -IEKYFVSPTLLRVVRVAKVGRVLRLVK---GAKGIRTLLFALAMSLPALFNICLLLFLV 1675
I K + + + ++ RV+RLVK +GIRTLL+ S AL + LL+ ++
Sbjct: 1260 NISKGMKGGSSIISINFFRLFRVMRLVKLLARGEGIRTLLWTFIKSFQALPYVALLIVML 1319
Query: 1676 MFIFAIFGMSFF--MHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVL---DGIIN 1730
FI+A+ GM F + + D+ + NF+TF Q++++LF+ +T W ++
Sbjct: 1320 FFIYAVIGMQVFGKIAMDDETSIHRNNNFQTFPQAVLVLFRSATGEAWQDIMLDCSSRPG 1379
Query: 1731 EEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEG 1790
E CD ++ GSP CGS I Y +S+ V+ ++IN+++AVI++N+ T D
Sbjct: 1380 EVNCDAKSDDAGSPEGCGS-NIAFPYFISFYVLCSFLIINLFVAVIMDNFDYLTRD-WSI 1437
Query: 1791 LTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHK--PNKY---KIISMDI 1845
L D + +W +DPD I++ + L + PPL K P++ +++SM++
Sbjct: 1438 LGPHHLDEFVRLWSEYDPDAKGRIKHLDVVTLLRKISPPLGFGKLCPHRVACKRLVSMNM 1497
Query: 1846 PI 1847
P+
Sbjct: 1498 PL 1499
Score = 135 bits (326), Expect = 1e-29
Identities = 92/312 (29%), Positives = 166/312 (53%), Gaps = 50/312 (16%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM----------PTTPTVEST 169
AL+ L NP+R++ I I+ F I+ TI NC+ + + T +E
Sbjct: 92 ALFCLTRTNPLRKLCIAIVEWKPFEYLILLTIFANCVALAVYTPFPNSDSNSTNAALEKI 151
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-----DLGNL 224
E IF I+T E +K++A GFIL P +YLR+ WN LDF ++ + ++ + + ++
Sbjct: 152 EYIFLVIFTAECIMKLIAYGFILHPGSYLRNGWNILDFTIVVIGMISTALSNLMKEGFDV 211
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
ALR FRVLR L+ V+ VP L+ ++ +++ ++ L + +L +F + ++A++GL+++ G
Sbjct: 212 KALRAFRVLRPLRLVSGVPSLQVVLNSILRAMVPLLHIALLVLFVIIIYAIIGLELFSGK 271
Query: 285 LTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQ 344
L + C + N T E ++ + GE G + C S P VC +
Sbjct: 272 LHKSC---------FHNETGE-----IMDDPHPCGEDGFH--CDTIS------PEMVC-R 308
Query: 345 GFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYW-ENLYQL-----------FFVVIIFLGS 392
+ PN+G T+FD FG + L+ F+ +T + W + LY + +F+ ++ LG+
Sbjct: 309 YYWEGPNFGITNFDNFGLSMLTVFQCVTLEGWTDMLYYIEDAMGSSWQWVYFISMVILGA 368
Query: 393 FYLVNLILAIVA 404
F+++NLIL +++
Sbjct: 369 FFVMNLILGVLS 380
Score = 107 bits (257), Expect = 3e-21
Identities = 76/272 (27%), Positives = 137/272 (50%), Gaps = 19/272 (6%)
Query: 1516 KAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIF 1575
K I R R + + V + F +I++ + LN + +HY+Q +Y NM F
Sbjct: 465 KTIDRINRRLRRACRKAVKSQAFYWLIIILVFLNTGVLATEHYRQPPWLDDFQEYTNMFF 524
Query: 1576 IVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVR 1634
+ +F+ E LLK+++L + YFV +N FD VV+ SI ++L+ + P + V+R
Sbjct: 525 VALFTMEMLLKMYSLGFQGYFVSLFNRFDCFVVIGSIGEMILT---STQIMPPLGVSVLR 581
Query: 1635 VAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKG 1694
++ RV ++ K + + L+ +L S+ ++ ++ LLLFL + IFA+ GM F +
Sbjct: 582 CVRLLRVFKVTKYWQSLSNLVASLLNSIQSIASLLLLLFLFIVIFALLGMQVFGGKFNFN 641
Query: 1695 GLDDV--YNFKTFVQSMILLFQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSAT 1751
D NF +FVQS++ +FQ+ T W+ V+ DGI + G
Sbjct: 642 SSVDKPRSNFDSFVQSLLTVFQILTGEDWNMVMYDGI------------QAYGGVASLGI 689
Query: 1752 IGITYLLSYLVISFLIVINMYIAVILENYSQA 1783
I Y + + I++N+++A+ ++N + A
Sbjct: 690 IASIYFIILFICGNYILLNVFLAIAVDNLADA 721
Score = 104 bits (249), Expect = 3e-20
Identities = 85/303 (28%), Positives = 146/303 (48%), Gaps = 36/303 (11%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPI--LQDILYYMDRIFTVIFF 1264
LR ++E FE ++ I + +ALA+ P+ L ++ IF VIF
Sbjct: 102 LRKLCIAIVEWKPFEYLILLTIFANCVALAVY-TPFPNSDSNSTNAALEKIEYIFLVIFT 160
Query: 1265 IEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRA 1320
E ++K +A GF Y N W LDF IV++ +I+ + G K +R R
Sbjct: 161 AECIMKLIAYGFILHPGSYLRNGWNILDFTIVVIGMISTALSNLMKEGFDV-KALRAFRV 219
Query: 1321 LRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMN 1380
LRPLR +S + ++VV+N++++A+ + ++ L+ L +I+AI+G++LF+GK K N
Sbjct: 220 LRPLRLVSGVPSLQVVLNSILRAMVPLLHIALLVLFVIIIYAIIGLELFSGKLHKSCFHN 279
Query: 1381 HTTLSHEIIPDKNAC--------TLE-----NYTWENSPM---NFDHVGKAYLCLFQVAT 1424
T EI+ D + C T+ Y WE NFD+ G + L +FQ T
Sbjct: 280 ET---GEIMDDPHPCGEDGFHCDTISPEMVCRYYWEGPNFGITNFDNFGLSMLTVFQCVT 336
Query: 1425 FKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQK 1484
+GW ++ D+ +G + + ++Y +NL +GV+ F++++
Sbjct: 337 LEGWTDMLYYIEDA--MG-------SSWQWVYFISMVILGAFFVMNLILGVLSGEFSKER 387
Query: 1485 KKA 1487
KA
Sbjct: 388 TKA 390
Score = 88.6 bits (210), Expect = 2e-15
Identities = 70/273 (25%), Positives = 122/273 (44%), Gaps = 29/273 (10%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
LR K +++ F +I ++ L++ LA E P P L D Y + F +F +E
Sbjct: 474 LRRACRKAVKSQAFYWLIIILVFLNTGVLATEHYRQP--PWLDDFQEYTNMFFVALFTME 531
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
ML+K +LGFQ YF + + D +V+ S+ + +R +R LR +
Sbjct: 532 MLLKMYSLGFQGYFVSLFNRFDCFVVIGSIGEMILTSTQIMPPLGVSVLRCVRLLRVFKV 591
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH 1386
Q + +V +L+ +I SI ++LL+ +F +IFA++G+Q+F GK+ N
Sbjct: 592 TKYWQSLSNLVASLLNSIQSIASLLLLLFLFIVIFALLGMQVFGGKF------NF----- 640
Query: 1387 EIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPI 1446
N + + NFD ++ L +FQ+ T + W +M D I + +
Sbjct: 641 ------------NSSVDKPRSNFDSFVQSLLTVFQILTGEDWNMVMYDGIQA----YGGV 684
Query: 1447 RETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDN 1479
I +Y LN+F+ + +DN
Sbjct: 685 ASLGIIASIYFIILFICGNYILLNVFLAIAVDN 717
Score = 87.0 bits (206), Expect = 5e-15
Identities = 50/177 (28%), Positives = 93/177 (52%), Gaps = 11/177 (6%)
Query: 118 TNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM--PTTPTVESTEVI--- 172
+NAL I P N R ++ H F I+ I+ + ++ P E +++
Sbjct: 833 SNALLIFSPTNRFRIFCHWLCNHSTFGNIILVCIMFSSAMLAAEDPLNANSERNQILNYF 892
Query: 173 ---FTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA--- 226
FT ++T E +K+++ GF+ + R A+N LD +V+ ++ ++M G ++
Sbjct: 893 DYFFTSVFTIELLLKLVSYGFLFHDGAFCRSAFNLLDLLVVCVSLISMFFSSGAISVIKI 952
Query: 227 LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
LR RVLR L+ + GLK +V VI +VK + +++++T +FA++G+Q+Y G
Sbjct: 953 LRVLRVLRPLRAINRAKGLKHVVQCVIVAVKTIGNIVLVTCLLQFMFAVIGVQLYKG 1009
Score = 84.2 bits (199), Expect = 3e-14
Identities = 54/185 (29%), Positives = 104/185 (56%), Gaps = 14/185 (7%)
Query: 1513 KPLKAI-PRPRWRP-QAIVFEIVTDKKFDMIIMLFIGLNMLTMTL-DHYQQSETFS--AV 1567
+P++A+ R P + + IV K F+ +I+L I N + + + + S++ S A
Sbjct: 88 RPMRALFCLTRTNPLRKLCIAIVEWKPFEYLILLTIFANCVALAVYTPFPNSDSNSTNAA 147
Query: 1568 LDYLNMIFIVIFSSECLLKIFALRY-----HYFVEPWNLFDFVVVMFSILSLVLSDIIEK 1622
L+ + IF+VIF++EC++K+ A + Y WN+ DF +V+ ++S LS+++++
Sbjct: 148 LEKIEYIFLVIFTAECIMKLIAYGFILHPGSYLRNGWNILDFTIVVIGMISTALSNLMKE 207
Query: 1623 YFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIF 1682
F ++ +R +V R LRLV G ++ +L ++ ++ L +I LL+ V+ I+AI
Sbjct: 208 GFD----VKALRAFRVLRPLRLVSGVPSLQVVLNSILRAMVPLLHIALLVLFVIIIYAII 263
Query: 1683 GMSFF 1687
G+ F
Sbjct: 264 GLELF 268
Score = 65.7 bits (153), Expect = 1e-08
Identities = 38/103 (36%), Positives = 62/103 (60%), Gaps = 9/103 (8%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGK--N 884
L+ LRVFK+ K W +L+ L++ + ++ ++ +L +L + I IFA++GMQ+FG N
Sbjct: 580 LRCVRLLRVFKVTKYWQSLSNLVASLLNSIQSIASLLLLLFLFIVIFALLGMQVFGGKFN 639
Query: 885 YVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWD 926
+ VD+ PR NF F+ S + VF++L GE W M+D
Sbjct: 640 FNSSVDK------PRSNFDSFVQSLLTVFQILTGEDWNMVMYD 676
Score = 57.2 bits (132), Expect = 4e-06
Identities = 42/155 (27%), Positives = 76/155 (49%), Gaps = 19/155 (12%)
Query: 142 LFSLFIITTILVNCILMIMPT--TPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLR 199
+F L +I TI ++ P T ++ +IFT ++ E K+ A F Y
Sbjct: 1181 IFVLIMINTITLSMKFYRQPEIYTEVLDLLNLIFTAVFALEFVFKLAAFRFK----NYFG 1236
Query: 200 DAWNWLDFVV-----IALAYVTMGIDLG--------NLAALRTFRVLRALKTVAIVPGLK 246
DAWN DF++ I + Y + I G ++ R FRV+R +K +A G++
Sbjct: 1237 DAWNVFDFIIVLGSFIDIVYSEVNISKGMKGGSSIISINFFRLFRVMRLVKLLARGEGIR 1296
Query: 247 TIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
T++ I+S + L V +L + ++A++G+Q++
Sbjct: 1297 TLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVF 1331
Score = 48.4 bits (110), Expect = 0.002
Identities = 34/124 (27%), Positives = 62/124 (50%), Gaps = 12/124 (9%)
Query: 167 ESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLD-FVVIA------LAYVTMGI 219
E T + F ++T E +K+ + GF Y +N D FVVI L +
Sbjct: 518 EYTNMFFVALFTMEMLLKMYSLGFQ----GYFVSLFNRFDCFVVIGSIGEMILTSTQIMP 573
Query: 220 DLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQ 279
LG ++ LR R+LR K L +V +++ S++++ +++L + +FAL+G+Q
Sbjct: 574 PLG-VSVLRCVRLLRVFKVTKYWQSLSNLVASLLNSIQSIASLLLLLFLFIVIFALLGMQ 632
Query: 280 IYMG 283
++ G
Sbjct: 633 VFGG 636
Score = 47.6 bits (108), Expect = 0.003
Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 6/105 (5%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
+R+ KL + L+ ++ AL + ++ ++ FI+AV+GMQ+FGK +D
Sbjct: 1283 MRLVKLLARGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIAMDDETSI 1342
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDC-MLVGDVSC 935
+ NF F + +++FR GE W + M DC G+V+C
Sbjct: 1343 HRNN----NFQTFPQAVLVLFRSATGEAWQDIMLDCSSRPGEVNC 1383
Score = 39.5 bits (88), Expect = 0.91
Identities = 20/77 (25%), Positives = 44/77 (57%)
Query: 805 IVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTF 864
+V+ + AL + + KAL++ LR +L P+L ++++ + R M L ++
Sbjct: 192 VVIGMISTALSNLMKEGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSILRAMVPLLHIAL 251
Query: 865 VLCIIIFIFAVMGMQLF 881
++ +I I+A++G++LF
Sbjct: 252 LVLFVIIIYAIIGLELF 268
>UniRef50_Q15878 Cluster: Voltage-dependent R-type calcium channel
subunit alpha-1E; n=59; Coelomata|Rep: Voltage-dependent
R-type calcium channel subunit alpha-1E - Homo sapiens
(Human)
Length = 2312
Score = 329 bits (808), Expect = 5e-88
Identities = 203/678 (29%), Positives = 357/678 (52%), Gaps = 39/678 (5%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
++ YFE ++ +I SS+ALA ED L + +L Y D +FT +F EM+IK +
Sbjct: 1148 IVNLRYFEMCILLVIAASSIALAAEDPVLTNSE-RNKVLRYFDYVFTGVFTFEMVIKMID 1206
Query: 1274 LGF----QKYFTNAWCWLDFIIVMVSLINFVAA-LCGAG---GIQAFKTMRTLRALRPLR 1325
G YF + W LDF++V+ +L+ F A G I+ K++R LR LRPL+
Sbjct: 1207 QGLILQDGSYFRDLWNILDFVVVVGALVAFALANALGTNKGRDIKTIKSLRVLRVLRPLK 1266
Query: 1326 AMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTT-- 1383
+ R+ ++ V + +V ++ ++FN+L+V +F IFA++ VQLF GK+F C D + T
Sbjct: 1267 TIKRLPKLKAVFDCVVTSLKNVFNILIVYKLFMFIFAVIAVQLFKGKFFYCTDSSKDTEK 1326
Query: 1384 --LSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREV 1441
+ + + +KN ++ W+ ++D++ A L LF V+T +GW Q++ ++D E
Sbjct: 1327 ECIGNYVDHEKNKMEVKGREWKRHEFHYDNIIWALLTLFTVSTGEGWPQVLQHSVDVTEE 1386
Query: 1442 GRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKK 1501
R P R + M ++ +N+F+ +II F EQ G M +K
Sbjct: 1387 DRGPSRSNRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQ-----GDKMMEECSLEKN 1441
Query: 1502 YYNAMKKMGSKKPL-KAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQ 1560
+ S KPL + +P+ R Q V+ V F+ IM I LN + + + +Y
Sbjct: 1442 ERACIDFAISAKPLTRYMPQNRHTFQYRVWHFVVSPSFEYTIMAMIALNTVVLMMKYYSA 1501
Query: 1561 SETFSAVLDYLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSLVLSD- 1618
T+ L YLN+ F ++FS EC+LK+ A + +YF + WN+FDF+ V+ SI ++L+D
Sbjct: 1502 PCTYELALKYLNIAFTMVFSLECVLKVIAFGFLNYFRDTWNIFDFITVIGSITEIILTDS 1561
Query: 1619 -IIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMF 1677
++ + + L++ R A R+++L++ IR LL+ S AL +CLL+ ++ F
Sbjct: 1562 KLVNTSGFNMSFLKLFRAA---RLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFF 1618
Query: 1678 IFAIFGMSFFMHVK--DKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECD 1735
I+AI GM F ++K ++ ++ NF++F S++LLF+ +T W ++ + E+ C+
Sbjct: 1619 IYAIIGMQVFGNIKLDEESHINRHNNFRSFFGSLMLLFRSATGEAWQEIMLSCLGEKGCE 1678
Query: 1736 LPDNERGSPGN----CGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGL 1791
PD S N CG+ + Y +S++ +++N+++AVI++N+ T D L
Sbjct: 1679 -PDTTAPSGQNENERCGT-DLAYVYFVSFIFFCSFLMLNLFVAVIMDNFEYLTRD-SSIL 1735
Query: 1792 TDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHK--PNK--YK-IISMDIP 1846
D + +W +D I Y ++ + L ++ PPL + K P+K YK ++ M++P
Sbjct: 1736 GPHHLDEFVRVWAEYDRAACGRIHYTEMYEMLTLMSPPLGLGKRCPSKVAYKRLVLMNMP 1795
Query: 1847 ICRGDMMFCVDILDALTK 1864
+ + L AL +
Sbjct: 1796 VAEDMTVHFTSTLMALIR 1813
Score = 134 bits (324), Expect = 2e-29
Identities = 95/316 (30%), Positives = 159/316 (50%), Gaps = 53/316 (16%)
Query: 115 FSATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM----------PTTP 164
F+ +L+I N +R+ A ++ P F I+ TI+ NCI++ + P +
Sbjct: 63 FTVNRSLFIFGEDNIVRKYAKKLIDWPPFEYMILATIIANCIVLALEQHLPEDDKTPMSR 122
Query: 165 TVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV-TMGIDLG- 222
+E TE F GI+ FE+ +K++A GFI +YLR+ WN +DF+V+ + T G
Sbjct: 123 RLEKTEPYFIGIFCFEAGIKIVALGFIFHKGSYLRNGWNVMDFIVVLSGILATAGTHFNT 182
Query: 223 --NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
+L LR RVLR LK V+ +P L+ ++ ++++++ L + +L F++ +FA++GL+
Sbjct: 183 HVDLRTLRAVRVLRPLKLVSGIPSLQIVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEF 242
Query: 281 YMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGY 340
Y G L + C F N + EG D P + G C GY
Sbjct: 243 YSGKLHRAC--------------------FMNN--SGILEGFDPP---HPCGVQGCPAGY 277
Query: 341 VCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWEN-LYQ-----------LFFVVII 388
C GPN G T FD +A L+ F+ +T + W LY L+F+ +I
Sbjct: 278 ECKDWIGPND--GITQFDNILFAVLTVFQCITMEGWTTVLYNTNDALGATWNWLYFIPLI 335
Query: 389 FLGSFYLVNLILAIVA 404
+GSF+++NL+L +++
Sbjct: 336 IIGSFFVLNLVLGVLS 351
Score = 104 bits (249), Expect = 3e-20
Identities = 61/183 (33%), Positives = 100/183 (54%), Gaps = 18/183 (9%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM--PTTPTVESTEV----- 171
++++I NPIRR YI+ F + I+ I + I + P E +V
Sbjct: 1130 SSMFIFSTTNPIRRACHYIVNLRYFEMCILLVIAASSIALAAEDPVLTNSERNKVLRYFD 1189
Query: 172 -IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM----------GID 220
+FTG++TFE +K++ +G ILQ +Y RD WN LDFVV+ A V G D
Sbjct: 1190 YVFTGVFTFEMVIKMIDQGLILQDGSYFRDLWNILDFVVVVGALVAFALANALGTNKGRD 1249
Query: 221 LGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
+ + +LR RVLR LKT+ +P LK + V+ S+KN+ +++I+ + +FA++ +Q+
Sbjct: 1250 IKTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVTSLKNVFNILIVYKLFMFIFAVIAVQL 1309
Query: 281 YMG 283
+ G
Sbjct: 1310 FKG 1312
Score = 89.0 bits (211), Expect = 1e-15
Identities = 75/289 (25%), Positives = 137/289 (47%), Gaps = 27/289 (9%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPH--RPILQDILYYMDRIFTVIFFIEMLIK 1270
KLI+ FE ++ I+ + + LALE HLP + + L + F IF E IK
Sbjct: 84 KLIDWPPFEYMILATIIANCIVLALEQ-HLPEDDKTPMSRRLEKTEPYFIGIFCFEAGIK 142
Query: 1271 WLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
+ALGF Y N W +DFI+V+ ++ A +T+R +R LRPL+
Sbjct: 143 IVALGFIFHKGSYLRNGWNVMDFIVVLSGIL--ATAGTHFNTHVDLRTLRAVRVLRPLKL 200
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH 1386
+S + +++V+ ++++A+ + + L+ L+FAI+G++ ++GK + MN++ +
Sbjct: 201 VSGIPSLQIVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYSGKLHRACFMNNSGILE 260
Query: 1387 EIIPDK----NACT--LENYTW---ENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAID 1437
P C E W + FD++ A L +FQ T +GW ++ + D
Sbjct: 261 GFDPPHPCGVQGCPAGYECKDWIGPNDGITQFDNILFAVLTVFQCITMEGWTTVLYNTND 320
Query: 1438 SREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
+ +G + +LY LNL +GV+ F +++++
Sbjct: 321 A--LGA-------TWNWLYFIPLIIIGSFFVLNLVLGVLSGEFAKERER 360
Score = 89.0 bits (211), Expect = 1e-15
Identities = 72/315 (22%), Positives = 142/315 (45%), Gaps = 35/315 (11%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
LR+ ++++ F V++++ L++ +A+ VH L +LYY + +F +F +E
Sbjct: 465 LRISIRHMVKSQVFYWIVLSLVALNTACVAI--VHHNQPQWLTHLLYYAEFLFLGLFLLE 522
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
M +K +G + YF +++ DF + + S+ V A+ G +R LR LR +
Sbjct: 523 MSLKMYGMGPRLYFHSSFNCFDFGVTVGSIFEVVWAIFRPGTSFGISVLRALRLLRIFKI 582
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH 1386
+R +V +L+ ++ SI ++L + +F ++FA++G+QLF G++
Sbjct: 583 TKYWASLRNLVVSLMSSMKSIISLLFLLFLFIVVFALLGMQLFGGRF------------- 629
Query: 1387 EIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPI 1446
N+ NFD A + +FQ+ T + W ++M + I S Q
Sbjct: 630 ------------NFNDGTPSANFDTFPAAIMTVFQILTGEDWNEVMYNGIRS-----QGG 672
Query: 1447 RETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAM 1506
+ ++ +Y LN+F+ + +DN ++ E +QK +A+
Sbjct: 673 VSSGMWSAIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAFNQK---HAL 729
Query: 1507 KKMGSKKPLKAIPRP 1521
+K P+ A P
Sbjct: 730 QKAKEVSPMSAPNMP 744
Score = 86.2 bits (204), Expect = 8e-15
Identities = 64/262 (24%), Positives = 123/262 (46%), Gaps = 19/262 (7%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR 1591
+V + F I++ + LN + + H+ Q + + +L Y +F+ +F E LK++ +
Sbjct: 472 MVKSQVFYWIVLSLVALNTACVAIVHHNQPQWLTHLLYYAEFLFLGLFLLEMSLKMYGMG 531
Query: 1592 YH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
YF +N FDF V + SI +V + ++LR +R+ R+ ++ K
Sbjct: 532 PRLYFHSSFNCFDFGVTVGSIFEVVWAIFRPGTSFGISVLRALRLL---RIFKITKYWAS 588
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMI 1710
+R L+ +L S+ ++ ++ LLFL + +FA+ GM F + NF TF +++
Sbjct: 589 LRNLVVSLMSSMKSIISLLFLLFLFIVVFALLGMQLFGGRFNFNDGTPSANFDTFPAAIM 648
Query: 1711 LLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVIN 1770
+FQ+ T W+ V+ I S G S Y + + ++N
Sbjct: 649 TVFQILTGEDWNEVMYNGIR------------SQGGVSSGMWSAIYFIVLTLFGNYTLLN 696
Query: 1771 MYIAVILENYSQA---TEDVQE 1789
+++A+ ++N + A T+D QE
Sbjct: 697 VFLAIAVDNLANAQELTKDEQE 718
Score = 68.1 bits (159), Expect = 2e-09
Identities = 41/102 (40%), Positives = 64/102 (62%), Gaps = 9/102 (8%)
Query: 827 LKSGNYLRVFKLAKSWPTL-NLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY 885
L++ LR+FK+ K W +L NL++S+M +M ++ +L F+L + I +FA++GMQLFG +
Sbjct: 571 LRALRLLRIFKITKYWASLRNLVVSLMS-SMKSIISLLFLLFLFIVVFALLGMQLFGGRF 629
Query: 886 VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWD 926
F DG P NF F + M VF++L GE W E M++
Sbjct: 630 -----NFNDG-TPSANFDTFPAAIMTVFQILTGEDWNEVMYN 665
Score = 65.7 bits (153), Expect = 1e-08
Identities = 48/158 (30%), Positives = 81/158 (51%), Gaps = 13/158 (8%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHY--QQSET-FSAVLDYLNMIFIVIFSSECLLKIFALRY-- 1592
F+ +I+ I N + + L+ + + +T S L+ FI IF E +KI AL +
Sbjct: 91 FEYMILATIIANCIVLALEQHLPEDDKTPMSRRLEKTEPYFIGIFCFEAGIKIVALGFIF 150
Query: 1593 ---HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
Y WN+ DF+VV+ IL+ + +F + LR +R +V R L+LV G
Sbjct: 151 HKGSYLRNGWNVMDFIVVLSGILATAGT-----HFNTHVDLRTLRAVRVLRPLKLVSGIP 205
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
++ +L ++ ++ L I LLLF + +FAI G+ F+
Sbjct: 206 SLQIVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFY 243
Score = 54.8 bits (126), Expect = 2e-05
Identities = 39/161 (24%), Positives = 78/161 (48%), Gaps = 19/161 (11%)
Query: 136 YILVHPLFSLFIITTILVNCILMIM-----PTTP--TVESTEVIFTGIYTFESAVKVMAR 188
+ +V P F I+ I +N ++++M P T ++ + FT +++ E +KV+A
Sbjct: 1472 HFVVSPSFEYTIMAMIALNTVVLMMKYYSAPCTYELALKYLNIAFTMVFSLECVLKVIAF 1531
Query: 189 GFILQPFTYLRDAWNWLDFV--------VIALAYVTMGIDLGNLAALRTFRVLRALKTVA 240
GF+ Y RD WN DF+ +I + N++ L+ FR R +K +
Sbjct: 1532 GFL----NYFRDTWNIFDFITVIGSITEIILTDSKLVNTSGFNMSFLKLFRAARLIKLLR 1587
Query: 241 IVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
++ ++ ++S K L V +L ++A++G+Q++
Sbjct: 1588 QGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF 1628
Score = 52.8 bits (121), Expect = 9e-05
Identities = 34/112 (30%), Positives = 56/112 (50%), Gaps = 7/112 (6%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
LK R+ KL + T+ +L+ ++ AL + ++ ++ FI+A++GMQ+FG +
Sbjct: 1574 LKLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIKL 1633
Query: 887 DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSCIP 937
D + NF F S M++FR GE W E M C+ G+ C P
Sbjct: 1634 DEESHINRHN----NFRSFFGSLMLLFRSATGEAWQEIMLSCL--GEKGCEP 1679
Score = 51.2 bits (117), Expect = 3e-04
Identities = 33/121 (27%), Positives = 60/121 (49%), Gaps = 12/121 (9%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVV-------IALAYVTMGIDLG 222
E +F G++ E ++K+ G P Y ++N DF V + A G G
Sbjct: 512 EFLFLGLFLLEMSLKMYGMG----PRLYFHSSFNCFDFGVTVGSIFEVVWAIFRPGTSFG 567
Query: 223 NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYM 282
++ LR R+LR K L+ +V +++ S+K++ ++ L + VFAL+G+Q++
Sbjct: 568 -ISVLRALRLLRIFKITKYWASLRNLVVSLMSSMKSIISLLFLLFLFIVVFALLGMQLFG 626
Query: 283 G 283
G
Sbjct: 627 G 627
>UniRef50_UPI000069E8BB Cluster: Voltage-dependent T-type calcium
channel subunit alpha-1I (Voltage- gated calcium channel
subunit alpha Cav3.3) (Ca(v)3.3).; n=4; Tetrapoda|Rep:
Voltage-dependent T-type calcium channel subunit alpha-1I
(Voltage- gated calcium channel subunit alpha Cav3.3)
(Ca(v)3.3). - Xenopus tropicalis
Length = 1715
Score = 328 bits (807), Expect = 7e-88
Identities = 188/602 (31%), Positives = 328/602 (54%), Gaps = 33/602 (5%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEM 1267
R+ +I + F+ V+ I L+ + +ALE + H+ + L + IFT IF EM
Sbjct: 1108 RIMCQTIIAHKLFDYVVLAFIFLNCITIALERPQIEHKSTERLFLSISNYIFTAIFVAEM 1167
Query: 1268 LIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQ---AFKTMRTLRA 1320
+K ++LG Q Y ++W LD +V VSLI+ V ++ AGG + + +R LR
Sbjct: 1168 TLKVVSLGLYFGDQAYLRSSWNILDGFLVFVSLIDIVVSVASAGGAKILGVLRVLRLLRT 1227
Query: 1321 LRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMN 1380
LRPLR +SR G+++VV L+ ++ I N++L+C F++IF I+GVQLF GK+F C+ ++
Sbjct: 1228 LRPLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFFYCLGVD 1287
Query: 1381 HTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSRE 1440
+ +K+ C NY W + NFD++G+A + LF +A+ GW+ IM + +D+
Sbjct: 1288 VRN-----VTNKSDCEAANYKWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYNGLDAVA 1342
Query: 1441 VGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQK 1500
V +QP+ N +M LY LN+F+GV+++NF+ K + E ++K
Sbjct: 1343 VDQQPVTNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFH--KCRQHQEAEEARRREEK 1400
Query: 1501 KYYNAMKKMGSK-KPLKAIPRPRWR----PQAIVFEIVTDKKFDMIIMLFIGLNMLTMTL 1555
+ KK SK KP +A P + + ++ + T D+ I + I LN++TM+L
Sbjct: 1401 RLRRLEKKRRSKRKPKEAQRLPYYATYCPARLLIHSVCTSHYLDIFITIIICLNVITMSL 1460
Query: 1556 DHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSL 1614
+HY Q + L Y N +F +F E +LK+ A + +F + WN D +V+ S++ +
Sbjct: 1461 EHYSQPRSLEIALKYCNYMFTTVFVLEAVLKLVAFGFRRFFKDRWNQLDLAIVLLSVMGI 1520
Query: 1615 VLSDI-IEKYF-VSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLL 1672
L +I I ++PT++R++RV ++ RVL+L+K A G+R LL + +LP + N+ LL
Sbjct: 1521 TLEEIEINAALPINPTIIRIMRVLRITRVLKLLKMATGMRALLDTVVQALPQVGNLGLLF 1580
Query: 1673 FLVMFIFAIFGMSFF--MHVKDK---GGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDG 1727
L+ FI+A G+ F + D G+ F+ F + + LFQ+ST W+G++
Sbjct: 1581 MLLFFIYAALGVELFGKLVCNDDHPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKD 1640
Query: 1728 IINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDV 1787
+ D ++R N I Y +S+++ + ++IN+ +AV++++ + ++
Sbjct: 1641 TLR----DCTSDDRSCLSNL--QFISPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEA 1694
Query: 1788 QE 1789
QE
Sbjct: 1695 QE 1696
Score = 95.9 bits (228), Expect = 1e-17
Identities = 59/200 (29%), Positives = 110/200 (55%), Gaps = 14/200 (7%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL- 1590
IV K F+ IM+ I +N ++M ++H++Q E + +L+ N++F +F+ E +LK+ A
Sbjct: 626 IVDSKYFNRGIMIAILVNTISMGIEHHEQPEELTNILEISNIVFTSMFALEMMLKLSAFG 685
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
+ Y P+N+FD ++V+ S+ ++ + L V+R ++ RVL+LV+
Sbjct: 686 LFDYLRNPYNIFDGIIVIISVWEIIGQ--------NDGGLSVLRTFRLLRVLKLVRFMPA 737
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF---MHVKDKGG--LDDVYNFKTF 1705
+R L L ++ + C+LL L +FIF+I GM F ++ G + D NF +
Sbjct: 738 LRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDSGDTVPDRKNFDSL 797
Query: 1706 VQSMILLFQMSTSAGWDGVL 1725
+ +++ +FQ+ T W+ VL
Sbjct: 798 LWAIVTVFQILTQEDWNVVL 817
Score = 94.7 bits (225), Expect = 2e-17
Identities = 59/160 (36%), Positives = 89/160 (55%), Gaps = 13/160 (8%)
Query: 1219 YFETAVITMILLSSLALAL----EDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLAL 1274
+FE + +ILL+ + L + EDV IL D + F +EM++K +AL
Sbjct: 1 WFECLSMMVILLNCVTLGMFQPCEDVDCSSERC--QILQVFDDFIFIFFAMEMVVKMVAL 58
Query: 1275 G-FQK--YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQ 1331
G F K Y + W LDF IVM ++ + L +RT+R LRPL+A++R+
Sbjct: 59 GIFGKKCYLGDTWNRLDFFIVMAGMVEYSLDLQNIN----LSAIRTVRVLRPLKAINRVP 114
Query: 1332 GMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
MR++VN L+ +P + NVLL+C + IF I+GVQL+AG
Sbjct: 115 SMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAG 154
Score = 87.8 bits (208), Expect = 3e-15
Identities = 69/290 (23%), Positives = 137/290 (47%), Gaps = 38/290 (13%)
Query: 1195 DDDSPFWQGW-GTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILY 1253
D D F +G G +R+K ++++ YF ++ IL++++++ +E P L +IL
Sbjct: 606 DGDEGFCKGLCGEVRVKLRGIVDSKYFNRGIMIAILVNTISMGIEHHEQPEE--LTNILE 663
Query: 1254 YMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFK 1313
+ +FT +F +EM++K A G Y N + D IIV++S+ + GG+ +
Sbjct: 664 ISNIVFTSMFALEMMLKLSAFGLFDYLRNPYNIFDGIIVIISVWEIIGQ--NDGGLSVLR 721
Query: 1314 TMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
T R LR L+ +R M ++ VV L++ + ++ ++ ++F IF+I+G+ +F K+
Sbjct: 722 TFRLLRVLKLVRFMPALRRQLVV---LMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKF 778
Query: 1374 FKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMN 1433
D S + +PD+ NFD + A + +FQ+ T + W ++
Sbjct: 779 SLRTD------SGDTVPDRK--------------NFDSLLWAIVTVFQILTQEDWNVVLY 818
Query: 1434 DAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQ 1483
+ + S T+ + LY NL + ++++ F +
Sbjct: 819 NGMAS----------TSPWAALYFVALMTFGNYVLFNLLVAILVEGFQAE 858
Score = 85.4 bits (202), Expect = 1e-14
Identities = 54/183 (29%), Positives = 94/183 (51%), Gaps = 20/183 (10%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVE--STE------- 170
++++ P N R + I+ H LF ++ I +NCI + + P +E STE
Sbjct: 1097 SIFLFSPQNRFRIMCQTIIAHKLFDYVVLAFIFLNCITIALER-PQIEHKSTERLFLSIS 1155
Query: 171 -VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLD--FVVIALAYVTMGID------- 220
IFT I+ E +KV++ G YLR +WN LD V ++L + + +
Sbjct: 1156 NYIFTAIFVAEMTLKVVSLGLYFGDQAYLRSSWNILDGFLVFVSLIDIVVSVASAGGAKI 1215
Query: 221 LGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
LG L LR R LR L+ ++ PGLK +V +I S+K + +++++ +F ++G+Q+
Sbjct: 1216 LGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQL 1275
Query: 281 YMG 283
+ G
Sbjct: 1276 FKG 1278
Score = 82.6 bits (195), Expect = 1e-13
Identities = 41/115 (35%), Positives = 69/115 (60%), Gaps = 3/115 (2%)
Query: 177 YTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN--LAALRTFRVLR 234
+ E VK++A G I YL D WN LDF ++ V +DL N L+A+RT RVLR
Sbjct: 47 FAMEMVVKMVALG-IFGKKCYLGDTWNRLDFFIVMAGMVEYSLDLQNINLSAIRTVRVLR 105
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKC 289
LK + VP ++ +V +++++ L +V++L F +F ++G+Q++ G+L +C
Sbjct: 106 PLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRC 160
Score = 70.9 bits (166), Expect = 3e-10
Identities = 43/147 (29%), Positives = 83/147 (56%), Gaps = 12/147 (8%)
Query: 143 FSLFIITTILVNCILMIMP-------TTPTVESTEVIFTGIYTFESAVKVMARGFILQPF 195
F+ I+ ILVN I M + T +E + ++FT ++ E +K+ A G F
Sbjct: 632 FNRGIMIAILVNTISMGIEHHEQPEELTNILEISNIVFTSMFALEMMLKLSAFGL----F 687
Query: 196 TYLRDAWNWLDFVVIALA-YVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIE 254
YLR+ +N D +++ ++ + +G + G L+ LRTFR+LR LK V +P L+ + +++
Sbjct: 688 DYLRNPYNIFDGIIVIISVWEIIGQNDGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMK 747
Query: 255 SVKNLRDVIILTMFSLSVFALMGLQIY 281
++ N+ +L M + +F+++G+ I+
Sbjct: 748 TMDNVATFCMLLMLFIFIFSILGMHIF 774
Score = 55.6 bits (128), Expect = 1e-05
Identities = 42/158 (26%), Positives = 72/158 (45%), Gaps = 15/158 (9%)
Query: 1538 FDMIIMLFIGLNMLTMTL----DHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL--- 1590
F+ + M+ I LN +T+ + + S +L + + F+ E ++K+ AL
Sbjct: 2 FECLSMMVILLNCVTLGMFQPCEDVDCSSERCQILQVFDDFIFIFFAMEMVVKMVALGIF 61
Query: 1591 -RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
+ Y + WN DF +VM ++ L + L +R +V R L+ +
Sbjct: 62 GKKCYLGDTWNRLDFFIVMAGMVEYSLD-------LQNINLSAIRTVRVLRPLKAINRVP 114
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+R L+ L +LP L N+ LL F V FIF I G+ +
Sbjct: 115 SMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLW 152
Score = 52.0 bits (119), Expect = 2e-04
Identities = 30/96 (31%), Positives = 50/96 (52%), Gaps = 7/96 (7%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY- 885
L++ LRV KL + P L + ++ +TM + +L + IFIF+++GM +FG +
Sbjct: 720 LRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFS 779
Query: 886 --VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE 919
D D PD R NF + + + VF++L E
Sbjct: 780 LRTDSGDTVPD----RKNFDSLLWAIVTVFQILTQE 811
Score = 50.0 bits (114), Expect = 6e-04
Identities = 26/94 (27%), Positives = 45/94 (47%), Gaps = 10/94 (10%)
Query: 1393 NACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIY 1452
N C N +NFD++G A++ +FQV T +GW++IM +D+ + Y
Sbjct: 245 NVCRTSNTNPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAH----------SFY 294
Query: 1453 MYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
++Y +NL + VI F+E K++
Sbjct: 295 NFIYFILLIIVGSFFMINLCLVVIATQFSETKQR 328
Score = 45.6 bits (103), Expect = 0.014
Identities = 21/70 (30%), Positives = 43/70 (61%), Gaps = 11/70 (15%)
Query: 349 NPNYGYTSFDTFGWAFLSAFRLMTQDYW-ENLYQ----------LFFVVIIFLGSFYLVN 397
NP+ G +FD G+A++ F+++T + W E +Y ++F+++I +GSF+++N
Sbjct: 253 NPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFILLIIVGSFFMIN 312
Query: 398 LILAIVAMSY 407
L L ++A +
Sbjct: 313 LCLVVIATQF 322
Score = 45.2 bits (102), Expect = 0.018
Identities = 29/96 (30%), Positives = 50/96 (52%), Gaps = 2/96 (2%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
RV KL K + L+ + + + +GNL + ++ FI+A +G++LFGK V D
Sbjct: 1548 RVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGK-LVCNDDHPC 1606
Query: 894 DGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
+G F +F +F+ +F+V G+ W M D +
Sbjct: 1607 EGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTL 1642
Score = 39.1 bits (87), Expect = 1.2
Identities = 16/56 (28%), Positives = 34/56 (60%)
Query: 826 ALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
A+++ LR K P++ +L++++ T+ LGN+ + + FIF ++G+QL+
Sbjct: 97 AIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLW 152
Score = 37.1 bits (82), Expect = 4.9
Identities = 13/38 (34%), Positives = 28/38 (73%)
Query: 796 FVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYL 833
++++FIT+ I +N + M+L+H++ + ++ ALK NY+
Sbjct: 1442 YLDIFITIIICLNVITMSLEHYSQPRSLEIALKYCNYM 1479
Score = 36.7 bits (81), Expect = 6.4
Identities = 14/49 (28%), Positives = 27/49 (55%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
LR ++ P L L++ + ++ +GN+ + C IF ++G+QLF
Sbjct: 1228 LRPLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQLF 1276
>UniRef50_A0D627 Cluster: Chromosome undetermined scaffold_39, whole
genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_39, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 1760
Score = 328 bits (806), Expect = 9e-88
Identities = 207/688 (30%), Positives = 361/688 (52%), Gaps = 39/688 (5%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+R F+ I + +I MIL+SS+ LAL+D P + +L +D + T+IF E
Sbjct: 977 IRRFAFRFINKSQVIGFIILMILVSSVLLALDD---PLQENNSAVLTEIDLVVTIIFTAE 1033
Query: 1267 MLIKWLALGFQ-----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRAL 1321
L+K LA GF Y + LDFI+++ S ++ + +Q FK +R R L
Sbjct: 1034 ALLKILAYGFFFNGEFSYMRDYANVLDFIVIIFSWVSIFSE----ANLQIFKILRIFRVL 1089
Query: 1322 RPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNH 1381
RPLR +SR +++ +NAL+ ++ IFN++LV L+F+ +F I G F G ++ C D+ H
Sbjct: 1090 RPLRLVSRSDSLKIAINALILSLSKIFNLILVSLVFYGMFGIFGTNFFKGAFYSC-DI-H 1147
Query: 1382 TTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREV 1441
++I+ K C W N+ NFD+ + LF ++T +GW+ M IDS +
Sbjct: 1148 KVGDYKIV-GKYDCFDYGGNWVNADYNFDNALNSISSLFVISTTEGWLDQMYQGIDSVGI 1206
Query: 1442 GRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKK 1501
+QPI N+Y L+ +NLF GV++D FN + K G +MT +Q++
Sbjct: 1207 DQQPIYNYNMYWSLFYIGFVIIGSFFVMNLFAGVVLDAFNSETDKLRGYF--YMTLEQQE 1264
Query: 1502 YYNAMKKMGSKKP-LKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQ 1560
+ + +++ KP + +W +A +F+I+ K FD +I + I +N + L + +Q
Sbjct: 1265 WVDIKERIYYAKPQINQRMSDQWF-RAKMFQIINHKYFDSMIFILITINTILFMLQYVRQ 1323
Query: 1561 SETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDII 1620
E + ++ Y N+ F+ IF++E L+K+ AL + YF EP+N FDFVVV+ SI VL +
Sbjct: 1324 PEVLNTIISYSNLAFLGIFTTEMLIKLIALGWQYFAEPFNRFDFVVVILSIAGSVLEQ-M 1382
Query: 1621 EKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFA 1680
T++ V R ++ R++RL++ A+ ++ + +++ L NI LL +++F+FA
Sbjct: 1383 SILTAFGTVISVFRSFRIVRIMRLIRSARSLKAIFETFFLTVSQLANIGGLLSIILFMFA 1442
Query: 1681 IFGMSFFMHVK-DKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINE-------- 1731
+ G++ F +VK GL D NF + ++ LF+ ST WD V ++ +
Sbjct: 1443 VLGINLFPYVKWSTTGLTDAINFSSLGKAFFTLFKCSTGEQWDQVQADLVRQIRPNNVCF 1502
Query: 1732 EECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGL 1791
E L D + CG G+ Y++S+ +I +I++N+++A+I++ Y +D +
Sbjct: 1503 SENLLTDYQTYGFNGCG-FWYGVAYMVSFQMIFAMIMLNLFVAIIVQGYEIIQKDEASSI 1561
Query: 1792 TDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPP-----LQIHKPNKYKIIS-MDI 1845
+ + + EIW+ +D GS I+ L F+ L P L + + K K I+ +
Sbjct: 1562 STNHIQAFIEIWKLYDQTGSGLIKALDLDRFMIKLPKPLGWKGLLLTQMEKRKFINQFRL 1621
Query: 1846 PIC---RGDMMFCVDILDALTKDFFARK 1870
P+ + M F D+L+ L+ + RK
Sbjct: 1622 PVYIKNQTAMYFFYDVLEVLSHNILTRK 1649
Score = 144 bits (349), Expect = 2e-32
Identities = 92/316 (29%), Positives = 163/316 (51%), Gaps = 39/316 (12%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMP--------TTPTVEST- 169
N+L++L+ N IR+ ++I+ F I I++N I + M T+ E T
Sbjct: 119 NSLYVLNESNIIRKYCVWIVTWHWFDKVITLIIVLNTISLAMQNYDFRVNGTSNQSELTY 178
Query: 170 -----EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNL 224
E FT ++ E +K++A GF+ + TYLRD WN LDF V+ + +++ + NL
Sbjct: 179 VRNQMEYFFTSVFLLEFILKILAMGFLFEKHTYLRDGWNVLDFAVVGTSILSL-VGSFNL 237
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
+A+RT R+LR L+++ VPGL+ +V ++++S+ NL +V++ ++ L +F ++GLQ++ G
Sbjct: 238 SAIRTIRILRPLRSIKSVPGLRILVASLLDSLPNLGNVLVFLLYLLVIFGILGLQLFAGA 297
Query: 285 LTQKC-VKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCL 343
+C FP +G+W D C +++ + D CGN
Sbjct: 298 YENRCRFTQFPVNGTWP--ADPLITHLCSSDS----DCPDNEFCGNPINYNLPNQDTPI- 350
Query: 344 QGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWEN------------LYQLFFVVIIFLG 391
P +Y YT+FD A + F+ +T + W L ++F ++I +G
Sbjct: 351 ----PELSYSYTTFDNILTATFTIFQALTTEGWSTMVTQLIDAVNPILVYVYFNLLIVIG 406
Query: 392 SFYLVNLILAIVAMSY 407
SF+ +NLILA++ S+
Sbjct: 407 SFFTINLILAVINDSF 422
Score = 107 bits (257), Expect = 3e-21
Identities = 93/336 (27%), Positives = 158/336 (47%), Gaps = 53/336 (15%)
Query: 1219 YFETAVITMILLSSLALALE--DVHLPHRPILQDILYY---MDRIFTVIFFIEMLIKWLA 1273
+F+ + +I+L++++LA++ D + ++ Y M+ FT +F +E ++K LA
Sbjct: 142 WFDKVITLIIVLNTISLAMQNYDFRVNGTSNQSELTYVRNQMEYFFTSVFLLEFILKILA 201
Query: 1274 LGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSR 1329
+GF Y + W LDF +V S+++ V G+ + A +RT+R LRPLR++
Sbjct: 202 MGFLFEKHTYLRDGWNVLDFAVVGTSILSLV----GSFNLSA---IRTIRILRPLRSIKS 254
Query: 1330 MQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-----FKCVDMN---- 1380
+ G+R++V +L+ ++P++ NVL+ L +IF I+G+QLFAG Y F +N
Sbjct: 255 VPGLRILVASLLDSLPNLGNVLVFLLYLLVIFGILGLQLFAGAYENRCRFTQFPVNGTWP 314
Query: 1381 ------HTTLSHEIIPDKNAC-TLENYTWEN----------SPMNFDHVGKAYLCLFQVA 1423
H S PD C NY N S FD++ A +FQ
Sbjct: 315 ADPLITHLCSSDSDCPDNEFCGNPINYNLPNQDTPIPELSYSYTTFDNILTATFTIFQAL 374
Query: 1424 TFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQ 1483
T +GW ++ ID+ I +Y+Y T+NL + VI D+F
Sbjct: 375 TTEGWSTMVTQLIDA---------VNPILVYVYFNLLIVIGSFFTINLILAVINDSF--L 423
Query: 1484 KKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIP 1519
K ++ E+ E Q+K KK ++ + P
Sbjct: 424 KNQSERRQELLKEEQQRKQQRKEKKQKERQNAQIHP 459
Score = 101 bits (243), Expect = 2e-19
Identities = 71/259 (27%), Positives = 130/259 (50%), Gaps = 24/259 (9%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY-HYFV 1596
F +++ I N + + +D Y Q E+ +L YLN+ F + F E +LK FAL YF
Sbjct: 557 FTIVVNCIIAANTVVLAMDRYPQPESEITILSYLNLAFTLFFVFEMVLKFFALGISEYFK 616
Query: 1597 EPWNLFDFVVVMFSILSLVLSDI-IEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLL 1655
+ N+FD +V S++ VL I S T + R +V R+ +L + +R +L
Sbjct: 617 DYMNIFDAFIVAISLVEQVLDFAEISVSGGSITAVSAFRTLRVFRIFKLARSWNSLREIL 676
Query: 1656 FALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDV-YNFKTFVQSMILLFQ 1714
A+A +L A+ +LL L M I ++ GM F + + DV NF TF +MI +F
Sbjct: 677 IAIATTLEAISFFTMLLLLFMVIASLVGMELFAY-----NIPDVRLNFDTFFDAMITIFA 731
Query: 1715 MSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIA 1774
+ TS W+ +L + + +++ P + + ++ +++ LI++ ++IA
Sbjct: 732 LLTSESWN-ILTYLY------MYKSDQWWP---------LIFFIAVVIMGNLILLKLFIA 775
Query: 1775 VILENYSQATEDVQEGLTD 1793
+++ N+ Q + ++ L D
Sbjct: 776 ILIYNFGQKAIETEKKLQD 794
Score = 79.8 bits (188), Expect = 7e-13
Identities = 52/173 (30%), Positives = 93/173 (53%), Gaps = 9/173 (5%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMP------TTPTVESTEVIF 173
+L+I D + IRR A + FII ILV+ +L+ + + + +++
Sbjct: 967 SLFIFDQTSKIRRFAFRFINKSQVIGFIILMILVSSVLLALDDPLQENNSAVLTEIDLVV 1026
Query: 174 TGIYTFESAVKVMARGFILQ-PFTYLRDAWNWLDFVVIALAYVTM--GIDLGNLAALRTF 230
T I+T E+ +K++A GF F+Y+RD N LDF+VI ++V++ +L LR F
Sbjct: 1027 TIIFTAEALLKILAYGFFFNGEFSYMRDYANVLDFIVIIFSWVSIFSEANLQIFKILRIF 1086
Query: 231 RVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
RVLR L+ V+ LK + A+I S+ + ++I++++ +F + G + G
Sbjct: 1087 RVLRPLRLVSRSDSLKIAINALILSLSKIFNLILVSLVFYGMFGIFGTNFFKG 1139
Score = 76.6 bits (180), Expect = 7e-12
Identities = 47/162 (29%), Positives = 82/162 (50%), Gaps = 6/162 (3%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
+ IE+ F V +I +++ LA++ P I IL Y++ FT+ F EM++K+
Sbjct: 550 RFIESLAFTIVVNCIIAANTVVLAMDRYPQPESEIT--ILSYLNLAFTLFFVFEMVLKFF 607
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLI----NFVAALCGAGGIQAFKTMRTLRALRPLRAMS 1328
ALG +YF + D IV +SL+ +F G I A RTLR R +
Sbjct: 608 ALGISEYFKDYMNIFDAFIVAISLVEQVLDFAEISVSGGSITAVSAFRTLRVFRIFKLAR 667
Query: 1329 RMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
+R ++ A+ + +I ++ L+F +I +++G++LFA
Sbjct: 668 SWNSLREILIAIATTLEAISFFTMLLLLFMVIASLVGMELFA 709
Score = 73.7 bits (173), Expect = 5e-11
Identities = 57/169 (33%), Positives = 85/169 (50%), Gaps = 24/169 (14%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQ--------QSETFSAVLDYLNMIFIVIFSSEC 1583
IVT FD +I L I LN +++ + +Y QSE + V + + F +F E
Sbjct: 137 IVTWHWFDKVITLIIVLNTISLAMQNYDFRVNGTSNQSE-LTYVRNQMEYFFTSVFLLEF 195
Query: 1584 LLKIFAL-----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKV 1638
+LKI A+ ++ Y + WN+ DF VV SILSLV S L +R ++
Sbjct: 196 ILKILAMGFLFEKHTYLRDGWNVLDFAVVGTSILSLVGS----------FNLSAIRTIRI 245
Query: 1639 GRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
R LR +K G+R L+ +L SLP L N+ + L ++ IF I G+ F
Sbjct: 246 LRPLRSIKSVPGLRILVASLLDSLPNLGNVLVFLLYLLVIFGILGLQLF 294
Score = 49.6 bits (113), Expect = 9e-04
Identities = 41/160 (25%), Positives = 75/160 (46%), Gaps = 20/160 (12%)
Query: 137 ILVHPLFSLFIITTILVNCILMIMPTT--PTVEST-----EVIFTGIYTFESAVKVMARG 189
I+ H F I I +N IL ++ P V +T + F GI+T E +K++A G
Sbjct: 1295 IINHKYFDSMIFILITINTILFMLQYVRQPEVLNTIISYSNLAFLGIFTTEMLIKLIALG 1354
Query: 190 FILQPFTYLRDAWNWLDFVVIALAYVTMGID-------LGN-LAALRTFRVLRALKTVAI 241
+ Y + +N DFVV+ L+ ++ G ++ R+FR++R ++ +
Sbjct: 1355 -----WQYFAEPFNRFDFVVVILSIAGSVLEQMSILTAFGTVISVFRSFRIVRIMRLIRS 1409
Query: 242 VPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
LK I +V L ++ L L +FA++G+ ++
Sbjct: 1410 ARSLKAIFETFFLTVSQLANIGGLLSIILFMFAVLGINLF 1449
Score = 48.0 bits (109), Expect = 0.003
Identities = 35/122 (28%), Positives = 61/122 (50%), Gaps = 12/122 (9%)
Query: 826 ALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY 885
A ++ R+FKLA+SW +L ++ + T+ A+ T +L + + I +++GM+LF N
Sbjct: 653 AFRTLRVFRIFKLARSWNSLREILIAIATTLEAISFFTMLLLLFMVIASLVGMELFAYN- 711
Query: 886 VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSC-IPFFLATV 943
PD R NF F + + +F +L E W + M D + FF+A V
Sbjct: 712 ------IPD---VRLNFDTFFDAMITIFALLTSESWNILTYLYMYKSDQWWPLIFFIAVV 762
Query: 944 VI 945
++
Sbjct: 763 IM 764
Score = 41.5 bits (93), Expect = 0.23
Identities = 27/92 (29%), Positives = 45/92 (48%), Gaps = 5/92 (5%)
Query: 828 KSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVD 887
+S +R+ +L +S +L + T+ L N+ +L II+F+FAV+G+ LF
Sbjct: 1396 RSFRIVRIMRLIRSARSLKAIFETFFLTVSQLANIGGLLSIILFMFAVLGINLF-----P 1450
Query: 888 YVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE 919
YV G NF+ +F +F+ GE
Sbjct: 1451 YVKWSTTGLTDAINFSSLGKAFFTLFKCSTGE 1482
Score = 39.5 bits (88), Expect = 0.91
Identities = 19/60 (31%), Positives = 35/60 (58%)
Query: 826 ALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY 885
A+++ LR + KS P L +L++ + ++ LGN+ L ++ IF ++G+QLF Y
Sbjct: 239 AIRTIRILRPLRSIKSVPGLRILVASLLDSLPNLGNVLVFLLYLLVIFGILGLQLFAGAY 298
>UniRef50_Q5PTC3 Cluster: Voltage gated sodium channel; n=142;
Pancrustacea|Rep: Voltage gated sodium channel -
Anopheles gambiae (African malaria mosquito)
Length = 166
Score = 323 bits (793), Expect = 3e-86
Identities = 149/166 (89%), Positives = 160/166 (96%), Gaps = 2/166 (1%)
Query: 1738 DNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYD 1797
DN++G PGNCGS+TIGITYLL+YLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYD
Sbjct: 1 DNDKGYPGNCGSSTIGITYLLAYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYD 60
Query: 1798 MYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHKPNKYKIISMDIPICRGDMMFCVD 1857
MYYEIWQ+FDPDG+QY+RYDQLSDFLDVLEPPLQIHKPN+YKIISMDIPICRGDMMFCVD
Sbjct: 61 MYYEIWQQFDPDGTQYVRYDQLSDFLDVLEPPLQIHKPNRYKIISMDIPICRGDMMFCVD 120
Query: 1858 ILDALTKDFFARKGNPIEETGDL-EV-GRPEEAGYEPVSSTLWRQR 1901
ILDALTKDFFARKGNPIEET +L EV RP+E GYEPVSSTLWRQ+
Sbjct: 121 ILDALTKDFFARKGNPIEETAELGEVQQRPDEVGYEPVSSTLWRQQ 166
>UniRef50_Q869H0 Cluster: Voltage-dependent T-type calcium channel
alpha-1 subunit; n=1; Lymnaea stagnalis|Rep:
Voltage-dependent T-type calcium channel alpha-1 subunit
- Lymnaea stagnalis (Great pond snail)
Length = 1942
Score = 321 bits (789), Expect = 1e-85
Identities = 200/653 (30%), Positives = 344/653 (52%), Gaps = 44/653 (6%)
Query: 1160 GKTDIKVGADEDVVDDTPADC--CPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKL--I 1215
G+ D D D +D+T +C CPE K FL + + F+ R++ F L I
Sbjct: 525 GREDDIDEPDPDAIDETEWNCSWCPEP---KGCFLERHEYA-FYLLSNENRIRKFALHLI 580
Query: 1216 ENTYFETAVITMILLSSLALALEDVHLPHRPILQD----ILYYMDRIFTVIFFIEMLIKW 1271
+F+ AV+ I L+ + LA+E +P I+ L Y + IFT +F +EM+IK
Sbjct: 581 SRKWFDNAVLFFIALNCITLAMERPDIPPDSIVSPEERYFLTYTNYIFTFVFALEMMIKV 640
Query: 1272 LALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAF---KTMRTLRALRPL 1324
+ GF Y + W +D +V++SLI+ + ++ + + F + R LR LRPL
Sbjct: 641 IGKGFFVGKHAYLKSGWNVMDGFLVIISLIDILISMSASSSPRIFGILRVFRLLRTLRPL 700
Query: 1325 RAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTL 1384
R +SR G+++VV L+ ++ I N++L+C F++IF I+GVQLF G ++ C N
Sbjct: 701 RVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGTFYHCKGPNILQ- 759
Query: 1385 SHEIIPDKNACTLE-NYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGR 1443
I +++ C + +W N NFD++G+A + LF +A+ GW+QIM +D+ + +
Sbjct: 760 ----ITNRSQCEADKKNSWINQKYNFDNLGQALMALFVLASKDGWVQIMYTGLDAVGIDQ 815
Query: 1444 QPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYY 1503
QPI N + +Y LN+F+GV+++NF+ K + +E K+
Sbjct: 816 QPIENYNEWRLIYFISFLLLVAFFVLNMFVGVVVENFH--KCRESQEIEERAKRAAKRQE 873
Query: 1504 NAMKKMGSKKPLKAIPR----PRW----RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTL 1555
KK S+ P + P W + ++ ++ K FD+ I IGLN++TM +
Sbjct: 874 KLDKKRKSEGPKASSSEMREPPYWAYYSHSRLLIHTVINSKYFDLAIAAVIGLNVITMAM 933
Query: 1556 DHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR-YHYFVEPWNLFDFVVVMFSILSL 1614
++Y E L N F +F E ++KI AL Y Y + WN D ++V+ SI+ +
Sbjct: 934 EYYMMPEELEFALKIFNFFFTSVFILEAVMKIIALGFYRYIRDRWNQLDIMIVILSIVGI 993
Query: 1615 VLSDIIEKYF-VSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLF 1673
VL ++ ++PT++RV+RV ++ RVL+L+K AKGIR LL + +LP + N+ LL F
Sbjct: 994 VLEEMRTNVIPINPTIIRVMRVLRIARVLKLLKMAKGIRALLDTVIQALPQVGNLGLLFF 1053
Query: 1674 LVMFIFAIFGMSFFMHV----KDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGII 1729
L+ FIFA G+ F + GL +F+ F + + LF+++T W+G++ +
Sbjct: 1054 LLFFIFAALGVELFGRLDCIDHPCEGLGVHAHFRNFGMAFLTLFRVATGDNWNGIMKDTL 1113
Query: 1730 NEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQ 1782
E+CD DN C S I Y + +++++ +++N+ +AV++++ +
Sbjct: 1114 -REDCDRADN--CLKNCCVSPLIAPVYFVVFVLMAQFVLVNVVVAVLMKHLEE 1163
Score = 83.4 bits (197), Expect = 6e-14
Identities = 70/294 (23%), Positives = 132/294 (44%), Gaps = 39/294 (13%)
Query: 1524 RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQ------QSETFSAVLDYLNMIFIV 1577
R + +++ K FD ++ FI LN +T+ ++ S L Y N IF
Sbjct: 571 RIRKFALHLISRKWFDNAVLFFIALNCITLAMERPDIPPDSIVSPEERYFLTYTNYIFTF 630
Query: 1578 IFSSECLLKI-----FALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRV 1632
+F+ E ++K+ F ++ Y WN+ D +V+ S++ +++S +LRV
Sbjct: 631 VFALEMMIKVIGKGFFVGKHAYLKSGWNVMDGFLVIISLIDILISMSASSSPRIFGILRV 690
Query: 1633 VRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM---- 1688
R+ + R LR++ A G++ ++ L SL + NI L+ IF I G+ F
Sbjct: 691 FRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGTFY 750
Query: 1689 HVK---------------DKGG--LDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINE 1731
H K DK ++ YNF Q+++ LF +++ GW ++ ++
Sbjct: 751 HCKGPNILQITNRSQCEADKKNSWINQKYNFDNLGQALMALFVLASKDGWVQIMYTGLDA 810
Query: 1732 EECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATE 1785
D E + + Y +S+L++ V+NM++ V++EN+ + E
Sbjct: 811 VGIDQQPIENYNEWR-------LIYFISFLLLVAFFVLNMFVGVVVENFHKCRE 857
Score = 80.6 bits (190), Expect = 4e-13
Identities = 48/186 (25%), Positives = 96/186 (51%), Gaps = 22/186 (11%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM--PTTPT-----------V 166
A ++L N IR+ A++++ F ++ I +NCI + M P P +
Sbjct: 562 AFYLLSNENRIRKFALHLISRKWFDNAVLFFIALNCITLAMERPDIPPDSIVSPEERYFL 621
Query: 167 ESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLD--FVVIALAYVTMGIDLGN- 223
T IFT ++ E +KV+ +GF + YL+ WN +D V+I+L + + + +
Sbjct: 622 TYTNYIFTFVFALEMMIKVIGKGFFVGKHAYLKSGWNVMDGFLVIISLIDILISMSASSS 681
Query: 224 ---LAALRTFRVLRALKTVAIV---PGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMG 277
LR FR+LR L+ + ++ PGLK +V ++ S++ + +++++ +F ++G
Sbjct: 682 PRIFGILRVFRLLRTLRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILG 741
Query: 278 LQIYMG 283
+Q++ G
Sbjct: 742 VQLFKG 747
Score = 61.7 bits (143), Expect = 2e-07
Identities = 58/244 (23%), Positives = 106/244 (43%), Gaps = 39/244 (15%)
Query: 1262 IFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRAL 1321
+F EM K A G Y +N + D IV++S++ GA G+ +T R LR L
Sbjct: 1 LFGTEMAFKISAYGLFGYISNGFNVFDGFIVILSIVELAQG--GASGLSVLRTFRLLRIL 58
Query: 1322 RPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNH 1381
+ +R M ++ VV+ + + + F +L+ +F IF+I+G+ LF K+ C+D
Sbjct: 59 KLVRFMPALRRQLVVMLRTMDNVATFFALLV---LFMFIFSILGMNLFGCKFCTCLDGGF 115
Query: 1382 TTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREV 1441
+ NFD + A + +FQV T + W ++ +
Sbjct: 116 RKCDRK--------------------NFDSLLWALITVFQVLTQEDWNTVLYNG------ 149
Query: 1442 GRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFN----EQKKKAGGSLEMFMTE 1497
+ +T+ + LY NL + ++++ F+ E+KK+ LE E
Sbjct: 150 ----MTKTSNWASLYFVALMTFGNYVLFNLLVAILVEGFSTEDEEKKKEKMKELEDVDKE 205
Query: 1498 DQKK 1501
D+++
Sbjct: 206 DEEE 209
Score = 59.7 bits (138), Expect = 8e-07
Identities = 41/168 (24%), Positives = 83/168 (49%), Gaps = 22/168 (13%)
Query: 132 RVAIYILVHP-LFSLFIITTILVNCILMIMPTTPTVESTEV-------IFTGIYTFESAV 183
R+ I+ +++ F L I I +N I M M E E FT ++ E+ +
Sbjct: 904 RLLIHTVINSKYFDLAIAAVIGLNVITMAMEYYMMPEELEFALKIFNFFFTSVFILEAVM 963
Query: 184 KVMARGFILQPFTYLRDAWNWLDFVVIALAYV----------TMGIDLGNLAALRTFRVL 233
K++A GF + Y+RD WN LD +++ L+ V + I+ + +R R+
Sbjct: 964 KIIALGF----YRYIRDRWNQLDIMIVILSIVGIVLEEMRTNVIPINPTIIRVMRVLRIA 1019
Query: 234 RALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
R LK + + G++ ++ VI+++ + ++ +L +FA +G++++
Sbjct: 1020 RVLKLLKMAKGIRALLDTVIQALPQVGNLGLLFFLLFFIFAALGVELF 1067
Score = 54.8 bits (126), Expect = 2e-05
Identities = 45/154 (29%), Positives = 74/154 (48%), Gaps = 14/154 (9%)
Query: 1578 IFSSECLLKIFALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVA 1636
+F +E KI A + Y +N+FD +V+ SI+ L + L V+R
Sbjct: 1 LFGTEMAFKISAYGLFGYISNGFNVFDGFIVILSIVELAQG--------GASGLSVLRTF 52
Query: 1637 KVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF---MHVKDK 1693
++ R+L+LV+ +R L + ++ + LL L MFIF+I GM+ F
Sbjct: 53 RLLRILKLVRFMPALRRQLVVMLRTMDNVATFFALLVLFMFIFSILGMNLFGCKFCTCLD 112
Query: 1694 GGLD--DVYNFKTFVQSMILLFQMSTSAGWDGVL 1725
GG D NF + + ++I +FQ+ T W+ VL
Sbjct: 113 GGFRKCDRKNFDSLLWALITVFQVLTQEDWNTVL 146
Score = 51.6 bits (118), Expect = 2e-04
Identities = 33/104 (31%), Positives = 55/104 (52%), Gaps = 4/104 (3%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L++ LR+ KL + P L + +M RTM + +L + +FIF+++GM LFG +
Sbjct: 49 LRTFRLLRILKLVRFMPALRRQLVVMLRTMDNVATFFALLVLFMFIFSILGMNLFGCKFC 108
Query: 887 DYVD-RFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
+D F D R NF + + + VF+VL E W +++ M
Sbjct: 109 TCLDGGFRKCD--RKNFDSLLWALITVFQVLTQEDWNTVLYNGM 150
Score = 51.2 bits (117), Expect = 3e-04
Identities = 28/107 (26%), Positives = 57/107 (53%), Gaps = 5/107 (4%)
Query: 176 IYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID-LGNLAALRTFRVLR 234
++ E A K+ A G F Y+ + +N D ++ L+ V + L+ LRTFR+LR
Sbjct: 1 LFGTEMAFKISAYGL----FGYISNGFNVFDGFIVILSIVELAQGGASGLSVLRTFRLLR 56
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
LK V +P L+ + ++ ++ N+ L + + +F+++G+ ++
Sbjct: 57 ILKLVRFMPALRRQLVVMLRTMDNVATFFALLVLFMFIFSILGMNLF 103
Score = 50.0 bits (114), Expect = 6e-04
Identities = 30/96 (31%), Positives = 53/96 (55%), Gaps = 3/96 (3%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
RV KL K + L+ + + + +GNL + ++ FIFA +G++LFG+ +D +D
Sbjct: 1020 RVLKLLKMAKGIRALLDTVIQALPQVGNLGLLFFLLFFIFAALGVELFGR--LDCIDHPC 1077
Query: 894 DGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
+G +F +F +F+ +FRV G+ W M D +
Sbjct: 1078 EGLGVHAHFRNFGMAFLTLFRVATGDNWNGIMKDTL 1113
Score = 37.1 bits (82), Expect = 4.9
Identities = 18/63 (28%), Positives = 35/63 (55%), Gaps = 11/63 (17%)
Query: 356 SFDTFGWAFLSAFRLMTQDYW-----------ENLYQLFFVVIIFLGSFYLVNLILAIVA 404
+FD+ WA ++ F+++TQ+ W N L+FV ++ G++ L NL++AI+
Sbjct: 122 NFDSLLWALITVFQVLTQEDWNTVLYNGMTKTSNWASLYFVALMTFGNYVLFNLLVAILV 181
Query: 405 MSY 407
+
Sbjct: 182 EGF 184
Score = 36.7 bits (81), Expect = 6.4
Identities = 14/49 (28%), Positives = 27/49 (55%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
LR ++ P L L++ + ++ +GN+ + C IF ++G+QLF
Sbjct: 697 LRPLRVISRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLF 745
>UniRef50_Q00975 Cluster: Voltage-dependent N-type calcium channel
subunit alpha-1B; n=68; Eumetazoa|Rep: Voltage-dependent
N-type calcium channel subunit alpha-1B - Homo sapiens
(Human)
Length = 2339
Score = 320 bits (787), Expect = 2e-85
Identities = 197/657 (29%), Positives = 342/657 (52%), Gaps = 33/657 (5%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
++ YFE ++ +I LSS+ALA ED P + L Y+D IFT +F EM+IK +
Sbjct: 1146 IVTMRYFEVVILVVIALSSIALAAEDPVRTDSP-RNNALKYLDYIFTGVFTFEMVIKMID 1204
Query: 1274 LGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSR 1329
LG YF + W LDFI+V +L+ F + I K++R LR LRPL+ + R
Sbjct: 1205 LGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSGSKGKDINTIKSLRVLRVLRPLKTIKR 1264
Query: 1330 MQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD----MNHTTLS 1385
+ ++ V + +V ++ ++ N+L+V ++F IFA++ VQLF GK+F C D +
Sbjct: 1265 LPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESKELERDCRG 1324
Query: 1386 HEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQP 1445
+ +K + W+ ++D+V A L LF V+T +GW ++ ++D+ + P
Sbjct: 1325 QYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATYEEQGP 1384
Query: 1446 IRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNA 1505
+ + ++ +N+F+ +II F EQ K + +K
Sbjct: 1385 SPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSL-----EKNERAC 1439
Query: 1506 MKKMGSKKPL-KAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETF 1564
+ S KPL + +P+ R Q + V F+ IM I LN + + + Y +
Sbjct: 1440 IDFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAPYEY 1499
Query: 1565 SAVLDYLNMIFIVIFSSECLLKIFALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIE-K 1622
+L LN++F +FS EC+LKI A +YF + WN+FDFV V+ SI +++++I E
Sbjct: 1500 ELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIAETN 1559
Query: 1623 YFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIF 1682
F++ + LR+ R A R+++L++ IR LL+ S AL +CLL+ ++ FI+AI
Sbjct: 1560 NFINLSFLRLFRAA---RLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAII 1616
Query: 1683 GMSFFMHV--KDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNE 1740
GM F ++ D ++ NF+TF+Q+++LLF+ +T W ++ ++ + CD E
Sbjct: 1617 GMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACD----E 1672
Query: 1741 RGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYY 1800
+ + CGS Y +S++ + +++N+++AVI++N+ T D L D +
Sbjct: 1673 QANATECGS-DFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRD-SSILGPHHLDEFI 1730
Query: 1801 EIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHK--PNK--YK-IISMDIPICRGDM 1852
+W +DP I Y+ + + L + PPL + K P + YK ++ M++PI DM
Sbjct: 1731 RVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDM 1787
Score = 154 bits (373), Expect = 3e-35
Identities = 98/313 (31%), Positives = 167/313 (53%), Gaps = 48/313 (15%)
Query: 115 FSATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM----------PTTP 164
F+ +L++ N +R+ A I P F I+ TI+ NCI++ + P +
Sbjct: 69 FTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPDGDKTPMSE 128
Query: 165 TVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV-TMGIDLGN 223
++ TE F GI+ FE+ +K++A GF+ +YLR+ WN +DFVV+ + T G D +
Sbjct: 129 RLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILATAGTDF-D 187
Query: 224 LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
L LR RVLR LK V+ +P L+ ++ ++++++ L + +L F++ +FA++GL+ YMG
Sbjct: 188 LRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYMG 247
Query: 284 VLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCL 343
+ C FP N TD GD+P CG + A CE C
Sbjct: 248 KFHKAC---FP------NSTDAE-------------PVGDFP-CGKEAPARLCEGDTECR 284
Query: 344 QGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWEN-LYQ-----------LFFVVIIFLG 391
+ + P PN+G T+FD +A L+ F+ +T + W + LY L+F+ +I +G
Sbjct: 285 E-YWPGPNFGITNFDNILFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIG 343
Query: 392 SFYLVNLILAIVA 404
SF+++NL+L +++
Sbjct: 344 SFFMLNLVLGVLS 356
Score = 111 bits (266), Expect = 2e-22
Identities = 58/179 (32%), Positives = 102/179 (56%), Gaps = 14/179 (7%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM--------PTTPTVESTE 170
++++ L P N +RR YI+ F + I+ I ++ I + P ++ +
Sbjct: 1128 SSMFCLSPTNLLRRFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLD 1187
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV------TMGIDLGNL 224
IFTG++TFE +K++ G +L P Y RD WN LDF+V++ A V + G D+ +
Sbjct: 1188 YIFTGVFTFEMVIKMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSGSKGKDINTI 1247
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
+LR RVLR LKT+ +P LK + V+ S+KN+ +++I+ M + +FA++ +Q++ G
Sbjct: 1248 KSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKG 1306
Score = 95.5 bits (227), Expect = 1e-17
Identities = 72/305 (23%), Positives = 134/305 (43%), Gaps = 32/305 (10%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
++++ F V+ ++ L++L +A+ + P R L LY+ + +F +F EM +K
Sbjct: 477 RMVKAQSFYWVVLCVVALNTLCVAMVHYNQPRR--LTTTLYFAEFVFLGLFLTEMSLKMY 534
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG 1332
LG + YF +++ DF +++ S+ V A G +R LR LR +
Sbjct: 535 GLGPRSYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSS 594
Query: 1333 MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDK 1392
+R +V +L+ ++ SI ++L + +F ++FA++G+QLF G++
Sbjct: 595 LRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQF------------------- 635
Query: 1393 NACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIY 1452
N+ E NFD A L +FQ+ T + W +M I+S Q ++
Sbjct: 636 ------NFQDETPTTNFDTFPAAILTVFQILTGEDWNAVMYHGIES-----QGGVSKGMF 684
Query: 1453 MYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSK 1512
Y LN+F+ + +DN ++ EM +QK K++
Sbjct: 685 SSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEEEMEEAANQKLALQKAKEVAEV 744
Query: 1513 KPLKA 1517
P+ A
Sbjct: 745 SPMSA 749
Score = 93.5 bits (222), Expect = 5e-17
Identities = 65/268 (24%), Positives = 126/268 (47%), Gaps = 21/268 (7%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR 1591
+V + F +++ + LN L + + HY Q + L + +F+ +F +E LK++ L
Sbjct: 478 MVKAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLG 537
Query: 1592 YH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
YF +N FDF V++ S+ +V + I ++LR +R+ R+ ++ K
Sbjct: 538 PRSYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLL---RIFKVTKYWSS 594
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMI 1710
+R L+ +L S+ ++ ++ LLFL + +FA+ GM F + NF TF +++
Sbjct: 595 LRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAIL 654
Query: 1711 LLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVIN 1770
+FQ+ T W+ V+ I S G Y + + ++N
Sbjct: 655 TVFQILTGEDWNAVMYHGIE------------SQGGVSKGMFSSFYFIVLTLFGNYTLLN 702
Query: 1771 MYIAVILENYSQATEDVQEGLTDDDYDM 1798
+++A+ ++N + A E LT D+ +M
Sbjct: 703 VFLAIAVDNLANAQE-----LTKDEEEM 725
Score = 90.6 bits (215), Expect = 4e-16
Identities = 78/285 (27%), Positives = 134/285 (47%), Gaps = 34/285 (11%)
Query: 1220 FETAVITMILLSSLALALEDVHLPH--RPILQDILYYMDRIFTVIFFIEMLIKWLALGFQ 1277
FE ++ I+ + + LALE HLP + + + L + F IF E IK +ALGF
Sbjct: 97 FEYMILATIIANCIVLALEQ-HLPDGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFV 155
Query: 1278 ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGM 1333
Y N W +DF++V+ + L AG +T+R +R LRPL+ +S + +
Sbjct: 156 FHKGSYLRNGWNVMDFVVVLTGI------LATAGTDFDLRTLRAVRVLRPLKLVSGIPSL 209
Query: 1334 RVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLS--HEIIPD 1391
+VV+ ++++A+ + + L+ L+FAI+G++ + GK+ K N T +
Sbjct: 210 QVVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYMGKFHKACFPNSTDAEPVGDFPCG 269
Query: 1392 KNA----CTLENYTWENSP------MNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREV 1441
K A C + E P NFD++ A L +FQ T +GW I+ + D+
Sbjct: 270 KEAPARLCEGDTECREYWPGPNFGITNFDNILFAILTVFQCITMEGWTDILYNTNDA--- 326
Query: 1442 GRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
N + +LY LNL +GV+ F +++++
Sbjct: 327 ------AGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERER 365
Score = 66.9 bits (156), Expect = 5e-09
Identities = 50/159 (31%), Positives = 77/159 (48%), Gaps = 17/159 (10%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQ---QSETFSAVLDYLNMIFIVIFSSECLLKIFALRY-- 1592
F+ +I+ I N + + L+ + S LD FI IF E +KI AL +
Sbjct: 97 FEYMILATIIANCIVLALEQHLPDGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVF 156
Query: 1593 ---HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
Y WN+ DFVVV+ IL+ +D LR +R +V R L+LV G
Sbjct: 157 HKGSYLRNGWNVMDFVVVLTGILATAGTDFD---------LRTLRAVRVLRPLKLVSGIP 207
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
++ +L ++ ++ L I LLLF + +FAI G+ F+M
Sbjct: 208 SLQVVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYM 246
Score = 61.7 bits (143), Expect = 2e-07
Identities = 37/101 (36%), Positives = 62/101 (61%), Gaps = 9/101 (8%)
Query: 827 LKSGNYLRVFKLAKSWPTL-NLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY 885
L++ LR+FK+ K W +L NL++S++ +M ++ +L F+L + I +FA++GMQLFG +
Sbjct: 577 LRALRLLRIFKVTKYWSSLRNLVVSLLN-SMKSIISLLFLLFLFIVVFALLGMQLFGGQF 635
Query: 886 VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMW 925
F D + P NF F + + VF++L GE W M+
Sbjct: 636 -----NFQD-ETPTTNFDTFPAAILTVFQILTGEDWNAVMY 670
Score = 60.9 bits (141), Expect = 3e-07
Identities = 41/158 (25%), Positives = 79/158 (50%), Gaps = 18/158 (11%)
Query: 138 LVHPLFSLFIITTILVNCILMIMP--TTP-----TVESTEVIFTGIYTFESAVKVMARGF 190
+V P F FI+ I +N ++++M P ++ ++FT +++ E +K++A G
Sbjct: 1468 VVSPPFEYFIMAMIALNTVVLMMKFYDAPYEYELMLKCLNIVFTSMFSMECVLKIIAFGV 1527
Query: 191 ILQPFTYLRDAWNWLDFVV-------IALAYVTMGIDLGNLAALRTFRVLRALKTVAIVP 243
+ Y RDAWN DFV I + + + NL+ LR FR R +K +
Sbjct: 1528 L----NYFRDAWNVFDFVTVLGSITDILVTEIAETNNFINLSFLRLFRAARLIKLLRQGY 1583
Query: 244 GLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
++ ++ ++S K L V +L ++A++G+Q++
Sbjct: 1584 TIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF 1621
Score = 57.6 bits (133), Expect = 3e-06
Identities = 37/128 (28%), Positives = 66/128 (51%), Gaps = 12/128 (9%)
Query: 163 TPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIA-------LAYV 215
T T+ E +F G++ E ++K+ G P +Y R ++N DF VI A +
Sbjct: 511 TTTLYFAEFVFLGLFLTEMSLKMYGLG----PRSYFRSSFNCFDFGVIVGSVFEVVWAAI 566
Query: 216 TMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFAL 275
G G ++ LR R+LR K L+ +V +++ S+K++ ++ L + VFAL
Sbjct: 567 KPGSSFG-ISVLRALRLLRIFKVTKYWSSLRNLVVSLLNSMKSIISLLFLLFLFIVVFAL 625
Query: 276 MGLQIYMG 283
+G+Q++ G
Sbjct: 626 LGMQLFGG 633
Score = 50.8 bits (116), Expect = 4e-04
Identities = 30/97 (30%), Positives = 53/97 (54%), Gaps = 7/97 (7%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
R+ KL + T+ +L+ ++ AL + ++ ++ FI+A++GMQ+FG +D
Sbjct: 1574 RLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALD-----D 1628
Query: 894 DGDLPRW-NFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
D + R NF F+ + M++FR GE W E M C+
Sbjct: 1629 DTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCL 1665
>UniRef50_O54898 Cluster: Voltage-dependent T-type calcium channel
subunit alpha-1G; n=81; Eumetazoa|Rep: Voltage-dependent
T-type calcium channel subunit alpha-1G - Rattus
norvegicus (Rat)
Length = 2254
Score = 320 bits (786), Expect = 2e-85
Identities = 185/602 (30%), Positives = 331/602 (54%), Gaps = 35/602 (5%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEM 1267
RL ++I + F+ V+ +I L+ + +A+E + + L + IFT +F EM
Sbjct: 1245 RLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAVFLAEM 1304
Query: 1268 LIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAF---KTMRTLRA 1320
+K +ALG+ Q Y ++W LD ++V++S+I+ + ++ G + + +R LR
Sbjct: 1305 TVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVLRLLRT 1364
Query: 1321 LRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMN 1380
LRPLR +SR QG+++VV L+ ++ I N++++C F++IF I+GVQLF GK+F C
Sbjct: 1365 LRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFVC--QG 1422
Query: 1381 HTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSRE 1440
T + I +K+ C +Y W NFD++G+A + LF +A+ GW+ IM D +D+
Sbjct: 1423 EDTRN---ITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG 1479
Query: 1441 VGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNF-----NEQKKKAGGSLEMFM 1495
V +QPI N +M LY LN+F+GV+++NF ++++++A E +
Sbjct: 1480 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL 1539
Query: 1496 TEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTL 1555
+KK + K+M ++ K R + +V + T D+ I IGLN++TM +
Sbjct: 1540 RRLEKKRRSKEKQM-AEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGVIGLNVVTMAM 1598
Query: 1556 DHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSL 1614
+HYQQ + L N IF VIF E + K+ A + +F + WN D +V+ SI+ +
Sbjct: 1599 EHYQQPQILDEALKICNYIFTVIFVFESVFKLVAFGFRRFFQDRWNQLDLAIVLLSIMGI 1658
Query: 1615 VLSDIIEKYF--VSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLL 1672
L +I ++PT++R++RV ++ RVL+L+K A G+R LL + +LP + N+ LL
Sbjct: 1659 TLEEIEVNLSLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLHTVMQALPQVGNLGLLF 1718
Query: 1673 FLVMFIFAIFGMSFFMHVK-DK----GGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDG 1727
L+ FIFA G+ F ++ D+ GL F+ F + + LF++ST W+G++
Sbjct: 1719 MLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVSTGDNWNGIMKD 1778
Query: 1728 IINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDV 1787
+ +CD C + I Y +S+++ + +++N+ IAV++++ ++ ++
Sbjct: 1779 TL--RDCD-------QESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKEA 1829
Query: 1788 QE 1789
+E
Sbjct: 1830 KE 1831
Score = 103 bits (248), Expect = 4e-20
Identities = 77/272 (28%), Positives = 135/272 (49%), Gaps = 42/272 (15%)
Query: 177 YTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLA--ALRTFRVLR 234
+ E VK++A G I YL D WN LDF ++ + +DL N++ A+RT RVLR
Sbjct: 128 FAVEMVVKMVALG-IFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVRTVRVLR 186
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKC----- 289
L+ + VP ++ +V +++++ L +V++L F +F ++G+Q++ G+L +C
Sbjct: 187 PLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLPEN 246
Query: 290 ------VKVFP------EDGS--WGNLTDENWERFCQNETNWYGEGGDYPLCG------N 329
V + P ED S + EN R C++ GEGG P C N
Sbjct: 247 FSLPLSVDLEPYYQTENEDESPFICSQPRENGMRSCRSVPTLRGEGGGGPPCSLDYETYN 306
Query: 330 SSGAGQC---EPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ----- 381
SS C Y NP G +FD G+A+++ F+++T + W ++
Sbjct: 307 SSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIMYFVMDA 366
Query: 382 ------LFFVVIIFLGSFYLVNLILAIVAMSY 407
++F+++I +GSF+++NL L ++A +
Sbjct: 367 HSFYNFIYFILLIIVGSFFMINLCLVVIATQF 398
Score = 101 bits (241), Expect = 3e-19
Identities = 78/300 (26%), Positives = 137/300 (45%), Gaps = 29/300 (9%)
Query: 1199 PFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRI 1258
P++ + RL L + Y + + +I L+ + +A+E H IL + L + I
Sbjct: 1560 PYYSDYSRFRLLVHHLCTSHYLDLFITGVIGLNVVTMAME--HYQQPQILDEALKICNYI 1617
Query: 1259 FTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFV-----AALCGAGGIQAFK 1313
FTVIF E + K +A GF+++F + W LD IV++S++ L +
Sbjct: 1618 FTVIFVFESVFKLVAFGFRRFFQDRWNQLDLAIVLLSIMGITLEEIEVNLSLPINPTIIR 1677
Query: 1314 TMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
MR LR R L+ + GMR +++ ++QA+P + N+ L+ ++ + IFA +GV+LF
Sbjct: 1678 IMRVLRIARVLKLLKMAVGMRALLHTVMQALPQVGNLGLLFMLLFFIFAALGVELFGD-- 1735
Query: 1374 FKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMN 1433
+C D H P + F + G A+L LF+V+T W IM
Sbjct: 1736 LEC-DETH--------PCEGL---------GRHATFRNFGMAFLTLFRVSTGDNWNGIMK 1777
Query: 1434 DAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEM 1493
D + R+ ++ + +Y +N+ I V++ + E K+A E+
Sbjct: 1778 DTL--RDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKEAKEEAEL 1835
Score = 97.1 bits (231), Expect = 4e-18
Identities = 72/280 (25%), Positives = 135/280 (48%), Gaps = 32/280 (11%)
Query: 1523 WRPQAIVFEIVTDKK-FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSS 1581
WR F + D K F IM+ I +N L+M +++++Q E + L+ N++F +F+
Sbjct: 730 WRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNIVFTSLFAL 789
Query: 1582 ECLLKIFALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGR 1640
E LLK+ + Y P+N+FD V+V+ S+ +V L V+R ++ R
Sbjct: 790 EMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQ--------GGGLSVLRTFRLMR 841
Query: 1641 VLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSF----FMHVKDKGGL 1696
VL+LV+ ++ L L ++ + C+LL L +FIF+I GM F +D L
Sbjct: 842 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL 901
Query: 1697 DDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITY 1756
D NF + + +++ +FQ+ T W+ VL G +++ Y
Sbjct: 902 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYN-----------------GMASTSSWAALY 944
Query: 1757 LLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDY 1796
++ + ++ N+ +A+++E + QA D + ++ D+
Sbjct: 945 FIALMTFGNYVLFNLLVAILVEGF-QAEGDATKSESEPDF 983
Score = 95.1 bits (226), Expect = 2e-17
Identities = 59/162 (36%), Positives = 91/162 (56%), Gaps = 13/162 (8%)
Query: 1217 NTYFETAVITMILLSSLALAL----EDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
N +FE + +ILL+ + L + ED+ + IL D F +EM++K +
Sbjct: 80 NPWFERVSMLVILLNCVTLGMFRPCEDIACDSQRCR--ILQAFDDFIFAFFAVEMVVKMV 137
Query: 1273 ALG-FQK--YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSR 1329
ALG F K Y + W LDF IV+ ++ + L +F +RT+R LRPLRA++R
Sbjct: 138 ALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNV----SFSAVRTVRVLRPLRAINR 193
Query: 1330 MQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
+ MR++V L+ +P + NVLL+C + IF I+GVQL+AG
Sbjct: 194 VPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 235
Score = 92.3 bits (219), Expect = 1e-16
Identities = 70/297 (23%), Positives = 144/297 (48%), Gaps = 36/297 (12%)
Query: 1521 PRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYL---NMIFIV 1577
P+ R + + I+T K FD ++++ I LN +T+ ++ + + SA +L N IF
Sbjct: 1240 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMER-PKIDPHSAERIFLTLSNYIFTA 1298
Query: 1578 IFSSECLLKIFALRY-----HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRV 1632
+F +E +K+ AL + Y WN+ D ++V+ S++ +++S + + +LRV
Sbjct: 1299 VFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRV 1358
Query: 1633 VRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF----- 1687
+R+ + R LR++ A+G++ ++ L SL + NI ++ IF I G+ F
Sbjct: 1359 LRLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFF 1418
Query: 1688 -------MHVKDKGGLDDV--------YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEE 1732
++ +K + YNF Q+++ LF +++ GW ++ ++
Sbjct: 1419 VCQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAV 1478
Query: 1733 ECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQE 1789
D +P + Y +S+L+I V+NM++ V++EN+ + + +E
Sbjct: 1479 GVDQQPIMNHNPWM-------LLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEE 1528
Score = 79.4 bits (187), Expect = 9e-13
Identities = 47/181 (25%), Positives = 91/181 (50%), Gaps = 20/181 (11%)
Query: 122 WILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVES----------TEV 171
+I P + R + I+ H +F ++ I +NCI + M P ++ +
Sbjct: 1236 YIFPPQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMER-PKIDPHSAERIFLTLSNY 1294
Query: 172 IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID---------LG 222
IFT ++ E VKV+A G+ YLR +WN LD +++ ++ + + + LG
Sbjct: 1295 IFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILG 1354
Query: 223 NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYM 282
L LR R LR L+ ++ GLK +V ++ S+K + +++++ +F ++G+Q++
Sbjct: 1355 MLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFK 1414
Query: 283 G 283
G
Sbjct: 1415 G 1415
Score = 77.8 bits (183), Expect = 3e-12
Identities = 63/271 (23%), Positives = 127/271 (46%), Gaps = 38/271 (14%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
K++++ YF ++ IL+++L++ +E P L + L + +FT +F +EML+K L
Sbjct: 739 KIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEE--LTNALEISNIVFTSLFALEMLLKLL 796
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG 1332
G Y N + D +IV++S+ V GG+ +T R +R L+ +R + +Q
Sbjct: 797 VYGPFGYIKNPYNIFDGVIVVISVWEIVGQQ--GGGLSVLRTFRLMRVLKLVRFLPALQR 854
Query: 1333 MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDK 1392
VV L++ + ++ ++ ++F IF+I+G+ LF K+ D + +PD+
Sbjct: 855 QLVV---LMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERD-------GDTLPDR 904
Query: 1393 NACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIY 1452
NFD + A + +FQ+ T + W +++ + + S T+ +
Sbjct: 905 K--------------NFDSLLWAIVTVFQILTQEDWNKVLYNGMAS----------TSSW 940
Query: 1453 MYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQ 1483
LY NL + ++++ F +
Sbjct: 941 AALYFIALMTFGNYVLFNLLVAILVEGFQAE 971
Score = 69.7 bits (163), Expect = 7e-10
Identities = 32/120 (26%), Positives = 72/120 (60%), Gaps = 5/120 (4%)
Query: 163 TPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALA-YVTMGIDL 221
T +E + ++FT ++ E +K++ G PF Y+++ +N D V++ ++ + +G
Sbjct: 773 TNALEISNIVFTSLFALEMLLKLLVYG----PFGYIKNPYNIFDGVIVVISVWEIVGQQG 828
Query: 222 GNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
G L+ LRTFR++R LK V +P L+ + +++++ N+ +L M + +F+++G+ ++
Sbjct: 829 GGLSVLRTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLF 888
Score = 57.6 bits (133), Expect = 3e-06
Identities = 50/174 (28%), Positives = 82/174 (47%), Gaps = 19/174 (10%)
Query: 1524 RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSA------VLDYLNMIFIV 1577
RP++ V + F+ + ML I LN +T+ + ++ E + +L +
Sbjct: 69 RPRSWCLRTVCNPWFERVSMLVILLNCVTLGM--FRPCEDIACDSQRCRILQAFDDFIFA 126
Query: 1578 IFSSECLLKIFAL----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVV 1633
F+ E ++K+ AL + Y + WN DF +V+ +L L + VS + +R V
Sbjct: 127 FFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSL----DLQNVSFSAVRTV 182
Query: 1634 RVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
RV R LR + +R L+ L +LP L N+ LL F V FIF I G+ +
Sbjct: 183 RVL---RPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLW 233
Score = 55.2 bits (127), Expect = 2e-05
Identities = 52/201 (25%), Positives = 99/201 (49%), Gaps = 29/201 (14%)
Query: 127 FNPIRRVAIYILVHPLFSLFIITTILVNCILMIMP--TTPTV--ESTEV---IFTGIYTF 179
++ R + ++ LFI I +N + M M P + E+ ++ IFT I+ F
Sbjct: 1565 YSRFRLLVHHLCTSHYLDLFITGVIGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVF 1624
Query: 180 ESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLG----NLA---------A 226
ES K++A GF + +D WN LD ++ L+ MGI L NL+
Sbjct: 1625 ESVFKLVAFGF----RRFFQDRWNQLDLAIVLLS--IMGITLEEIEVNLSLPINPTIIRI 1678
Query: 227 LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLT 286
+R R+ R LK + + G++ ++ V++++ + ++ +L M +FA +G++++ G L
Sbjct: 1679 MRVLRIARVLKLLKMAVGMRALLHTVMQALPQVGNLGLLFMLLFFIFAALGVELF-GDL- 1736
Query: 287 QKCVKVFPEDGSWGNLTDENW 307
+C + P +G + T N+
Sbjct: 1737 -ECDETHPCEGLGRHATFRNF 1756
Score = 54.0 bits (124), Expect = 4e-05
Identities = 36/118 (30%), Positives = 63/118 (53%), Gaps = 7/118 (5%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L++ +RV KL + P L + ++ +TM + +L + IFIF+++GM LFG +
Sbjct: 834 LRTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFA 893
Query: 887 DYVDRFPDGD-LP-RWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSCIPFFLA 941
+R DGD LP R NF + + + VF++L E W + +++ M +F+A
Sbjct: 894 S--ER--DGDTLPDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIA 947
Score = 45.2 bits (102), Expect = 0.018
Identities = 24/92 (26%), Positives = 44/92 (47%), Gaps = 10/92 (10%)
Query: 1395 CTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMY 1454
C+ + +NFD++G A++ +FQV T +GW+ IM +D+ + Y +
Sbjct: 323 CSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIMYFVMDAH----------SFYNF 372
Query: 1455 LYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
+Y +NL + VI F+E K++
Sbjct: 373 IYFILLIIVGSFFMINLCLVVIATQFSETKQR 404
Score = 45.2 bits (102), Expect = 0.018
Identities = 31/97 (31%), Positives = 50/97 (51%), Gaps = 4/97 (4%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
RV KL K + L+ + + + +GNL + ++ FIFA +G++LFG D + P
Sbjct: 1686 RVLKLLKMAVGMRALLHTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLECD--ETHP 1743
Query: 894 DGDLPRW-NFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
L R F +F +F+ +FRV G+ W M D +
Sbjct: 1744 CEGLGRHATFRNFGMAFLTLFRVSTGDNWNGIMKDTL 1780
Score = 38.3 bits (85), Expect = 2.1
Identities = 19/77 (24%), Positives = 42/77 (54%), Gaps = 3/77 (3%)
Query: 805 IVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTF 864
++ L +LD N+ A+++ LR + P++ +L++++ T+ LGN+
Sbjct: 160 VIAGMLEYSLDLQNVSFS---AVRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLL 216
Query: 865 VLCIIIFIFAVMGMQLF 881
+ + FIF ++G+QL+
Sbjct: 217 LCFFVFFIFGIVGVQLW 233
Score = 37.1 bits (82), Expect = 4.9
Identities = 21/89 (23%), Positives = 42/89 (47%), Gaps = 1/89 (1%)
Query: 799 LFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGA 858
L + + ++ + M D M + L+ LR ++ L L++ + ++
Sbjct: 1331 LLVLISVIDILVSMVSDSGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLKP 1390
Query: 859 LGNLTFVLCIIIFIFAVMGMQLF-GKNYV 886
+GN+ + C IF ++G+QLF GK +V
Sbjct: 1391 IGNIVVICCAFFIIFGILGVQLFKGKFFV 1419
Score = 36.7 bits (81), Expect = 6.4
Identities = 18/63 (28%), Positives = 36/63 (57%), Gaps = 11/63 (17%)
Query: 356 SFDTFGWAFLSAFRLMTQDYWEN-LYQ----------LFFVVIIFLGSFYLVNLILAIVA 404
+FD+ WA ++ F+++TQ+ W LY L+F+ ++ G++ L NL++AI+
Sbjct: 906 NFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLVAILV 965
Query: 405 MSY 407
+
Sbjct: 966 EGF 968
Score = 36.7 bits (81), Expect = 6.4
Identities = 18/50 (36%), Positives = 31/50 (62%)
Query: 784 FQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYL 833
F+ V L +++LFIT I +N + MA++H+ + +D+ALK NY+
Sbjct: 1568 FRLLVHHLCTSHYLDLFITGVIGLNVVTMAMEHYQQPQILDEALKICNYI 1617
>UniRef50_O02038 Cluster: Voltage-gated calcium channel alpha-1
subunit; n=5; Cnidaria|Rep: Voltage-gated calcium channel
alpha-1 subunit - Cyanea capillata (Lion's mane
jellyfish)
Length = 1911
Score = 319 bits (783), Expect = 6e-85
Identities = 199/645 (30%), Positives = 345/645 (53%), Gaps = 37/645 (5%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQD-ILYYMDRIFTVIFFI 1265
LR ++L N F +++ +I++SS+ALA ED R +L++ IL Y D FT +F
Sbjct: 858 LRYLCYRLAVNKIFINSILVLIIMSSVALAAEDPI--GRDVLRNKILGYFDIFFTAMFTF 915
Query: 1266 EMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRAL 1321
E+ +K +A G + + + + LD +IV VS + + A + + +R LR L
Sbjct: 916 EVTVKMIAFGVILHKRSFCRSFFNQLDLVIVAVSWAAIMLSRGSATSV--VRILRVLRVL 973
Query: 1322 RPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNH 1381
RPLRA++R +G++ VV + AI SI N+++V L+F +FA++G+QLF G +F C D +
Sbjct: 974 RPLRAINRAKGLKHVVQCVFLAIKSIGNIMIVTLLFQFLFAVIGIQLFKGTFFYCTDRSK 1033
Query: 1382 TTL-----SHEIIPDKNAC--TLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMND 1434
T + P+ N + TWE FD+V +AYL LF V TF+GW I+
Sbjct: 1034 MTAEECKGTFNSYPEVNLANPVVAARTWEKHTFRFDNVFQAYLSLFVVMTFEGWPSILEH 1093
Query: 1435 AIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMF 1494
+IDS V + P ++ +Y +N+F+G +I F + ++ E
Sbjct: 1094 SIDSTTVNQGPKFNNRPFVAIYYVIYIIIIAFFMINIFVGFVIVTFQNEGEEEFADCE-- 1151
Query: 1495 MTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMT 1554
+ ++Q+K + + K + +PR R+ Q ++ +VT + F+ +I FI N + +
Sbjct: 1152 LDKNQRKCVEYV--LTVKPTYRFVPRKRF--QYHIWRVVTSRLFEYMIFGFILGNTIVLA 1207
Query: 1555 LDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR-YHYFVEPWNLFDFVVVMFSILS 1613
++ S+ + VLD N+ F +F EC+LK+ A +YF +PWN+FDFV+V+ SI
Sbjct: 1208 AQYHNASKLYERVLDGFNIGFTAVFLLECVLKLMAFNAKNYFRDPWNIFDFVIVVGSIAD 1267
Query: 1614 LVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLF 1673
+++ +I + + R+ R R+++L+ GIRTLL+ S AL + LL+
Sbjct: 1268 IIIGEISKDGGIKVNFFRLFRAL---RLVKLLSQGDGIRTLLWTFMKSFQALPFVGLLIL 1324
Query: 1674 LVMFIFAIFGMSFFMHVKDKGG--LDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINE 1731
L+ FI+A+ GM F ++ G ++ NF+TF Q++I+LF+ +T W ++ +N
Sbjct: 1325 LLFFIYAVIGMQVFGTIRLDSGTVINSNNNFQTFPQALIVLFRSATGENWQQIMMACVNS 1384
Query: 1732 E--ECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQE 1789
E +C++ ++ CG+ + ++ Y++ SFLI IN+++AVI++N+ T D
Sbjct: 1385 ESVKCEVDPSK-----TCGTDFAYLYFMSFYMICSFLI-INLFVAVIMDNFDYLTRD-WS 1437
Query: 1790 GLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHK 1834
L + Y IW +DP+ S +++ + L +EPPL K
Sbjct: 1438 ILGAHHLEEYVRIWAEYDPEASGRMKHVDIVSMLKRIEPPLGFGK 1482
Score = 135 bits (327), Expect = 1e-29
Identities = 93/312 (29%), Positives = 155/312 (49%), Gaps = 49/312 (15%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMI----MP------TTPTVEST 169
AL+ L NP+R AI I+ F FI+ +I NC + +P T +E
Sbjct: 92 ALFCLTLDNPVRSAAITIVDWKPFDFFILASIFANCAALAAYEPLPAGDMTSTNQDLEVA 151
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID----LG-NL 224
E F ++ E +K++A GFIL P YLR+ WN LDF ++ + + +M + G ++
Sbjct: 152 EYFFLAVFAIEGLLKIIAYGFILHPGAYLRNGWNILDFSIVVIGFASMIFEEYLKSGFDV 211
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
ALR FRVLR L+ V+ VP L+ ++ ++++++ L + +L +F + ++A++G++++ G
Sbjct: 212 KALRAFRVLRPLRLVSGVPSLQVVMNSIVKAMLPLFHIALLVVFVIIIYAIIGVELFTGK 271
Query: 285 LTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQ 344
L Q C N TN P +S QC G +C
Sbjct: 272 LHQTCY---------------------DNITNLPASSEPKPCSTTTSYGRQCPSGSICKN 310
Query: 345 GFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWEN-LYQ-----------LFFVVIIFLGS 392
+ PNYG T+FD A L+ F+ T + W + LY ++FV +I GS
Sbjct: 311 NW-EGPNYGITNFDNVALAALTVFQCTTLEGWTDVLYDINNVSGGGWPWIYFVTLITFGS 369
Query: 393 FYLVNLILAIVA 404
F+++NLIL +++
Sbjct: 370 FFVLNLILGVLS 381
Score = 101 bits (242), Expect = 2e-19
Identities = 87/321 (27%), Positives = 143/321 (44%), Gaps = 31/321 (9%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALAL-EDVHLPHRPILQDILYYMDRIFTVIFFI 1265
+R +++ F+ ++ I + ALA E + L + F +F I
Sbjct: 102 VRSAAITIVDWKPFDFFILASIFANCAALAAYEPLPAGDMTSTNQDLEVAEYFFLAVFAI 161
Query: 1266 EMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRAL 1321
E L+K +A GF Y N W LDF IV++ + + G K +R R L
Sbjct: 162 EGLLKIIAYGFILHPGAYLRNGWNILDFSIVVIGFASMIFEEYLKSGFDV-KALRAFRVL 220
Query: 1322 RPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNH 1381
RPLR +S + ++VV+N++V+A+ +F++ L+ + +I+AI+GV+LF GK + N
Sbjct: 221 RPLRLVSGVPSLQVVMNSIVKAMLPLFHIALLVVFVIIIYAIIGVELFTGKLHQTCYDNI 280
Query: 1382 TTLSHEIIPDKNACTLENY------------TWEN---SPMNFDHVGKAYLCLFQVATFK 1426
T L P K T +Y WE NFD+V A L +FQ T +
Sbjct: 281 TNLPASSEP-KPCSTTTSYGRQCPSGSICKNNWEGPNYGITNFDNVALAALTVFQCTTLE 339
Query: 1427 GWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
GW ++ D I++ G P ++Y LNL +GV+ F ++K +
Sbjct: 340 GWTDVLYD-INNVSGGGWP--------WIYFVTLITFGSFFVLNLILGVLSGEFAKEKAR 390
Query: 1487 AGGSLEMFMTEDQKKYYNAMK 1507
S E ++ +A+K
Sbjct: 391 QTKSGEFHKIREKHMLDDAVK 411
Score = 97.1 bits (231), Expect = 4e-18
Identities = 72/258 (27%), Positives = 137/258 (53%), Gaps = 23/258 (8%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR 1591
IV + F ++++ + LN L + ++HY Q + + LD N F+ +F+ E LLKI+ L
Sbjct: 493 IVKSQTFYWMVIIAVFLNSLVLAVEHYDQPDYITMFLDRANYFFLGLFTFEMLLKIYCLG 552
Query: 1592 -YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
Y Y +N FD +VV+ S+L + ++ + ++LR VR+ ++ +V R +
Sbjct: 553 IYGYLNSLFNRFDCLVVLSSLLEVAITVPTGWPPIGISVLRCVRLLRIFKVTRY---WES 609
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDV----YNFKTFV 1706
+ L+ +L S+ ++ ++ LLL L + IF++ GM F + LD+ NF +F
Sbjct: 610 LSNLVQSLVNSIKSIGSLLLLLSLFILIFSLLGMQIF---GGRFNLDEQAPPRTNFDSFW 666
Query: 1707 QSMILLFQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISF 1765
+S+I +FQ+ T W+ V+ GI G N S+ I I Y ++ +++
Sbjct: 667 RSLITVFQILTGEDWNAVMYVGI----------QSWGGIKN-PSSIIAIIYFVALVIVGN 715
Query: 1766 LIVINMYIAVILENYSQA 1783
I++N+++A+ ++N + A
Sbjct: 716 YILLNVFLAIAVDNLADA 733
Score = 80.2 bits (189), Expect = 5e-13
Identities = 74/307 (24%), Positives = 134/307 (43%), Gaps = 32/307 (10%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
LR + ++++ F VI + L+SL LA+E H + L + F +F E
Sbjct: 486 LRRQCRGIVKSQTFYWMVIIAVFLNSLVLAVE--HYDQPDYITMFLDRANYFFLGLFTFE 543
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
ML+K LG Y + + D ++V+ SL+ + +R +R LR +
Sbjct: 544 MLLKIYCLGIYGYLNSLFNRFDCLVVLSSLLEVAITVPTGWPPIGISVLRCVRLLRIFKV 603
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH 1386
+ + +V +LV +I SI ++LL+ +F LIF+++G+Q+F G++ L
Sbjct: 604 TRYWESLSNLVQSLVNSIKSIGSLLLLLSLFILIFSLLGMQIFGGRF---------NLDE 654
Query: 1387 EIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPI 1446
+ P NFD ++ + +FQ+ T + W +M I S + P
Sbjct: 655 QAPP---------------RTNFDSFWRSLITVFQILTGEDWNAVMYVGIQSWGGIKNP- 698
Query: 1447 RETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAM 1506
++I +Y LN+F+ + +DN + + + E + +KK M
Sbjct: 699 --SSIIAIIYFVALVIVGNYILLNVFLAIAVDNLADAENMTKVNEE---EKRKKKDAKLM 753
Query: 1507 KKMGSKK 1513
KK+ KK
Sbjct: 754 KKLARKK 760
Score = 79.4 bits (187), Expect = 9e-13
Identities = 38/118 (32%), Positives = 74/118 (62%), Gaps = 4/118 (3%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA--- 226
++ FT ++TFE VK++A G IL ++ R +N LD V++A+++ + + G+ +
Sbjct: 906 DIFFTAMFTFEVTVKMIAFGVILHKRSFCRSFFNQLDLVIVAVSWAAIMLSRGSATSVVR 965
Query: 227 -LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
LR RVLR L+ + GLK +V V ++K++ +++I+T+ +FA++G+Q++ G
Sbjct: 966 ILRVLRVLRPLRAINRAKGLKHVVQCVFLAIKSIGNIMIVTLLFQFLFAVIGIQLFKG 1023
Score = 68.5 bits (160), Expect = 2e-09
Identities = 57/216 (26%), Positives = 99/216 (45%), Gaps = 13/216 (6%)
Query: 1494 FMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTM 1553
+ T+ KK A + + K+ L + A + IV K FD I+ I N +
Sbjct: 72 YPTKKTKKQPGAGQNLRPKRALFCLTLDNPVRSAAI-TIVDWKPFDFFILASIFANCAAL 130
Query: 1554 TLDHYQQSETFSAV---LDYLNMIFIVIFSSECLLKIFALRY--H---YFVEPWNLFDFV 1605
+ ++ L+ F+ +F+ E LLKI A + H Y WN+ DF
Sbjct: 131 AAYEPLPAGDMTSTNQDLEVAEYFFLAVFAIEGLLKIIAYGFILHPGAYLRNGWNILDFS 190
Query: 1606 VVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPAL 1665
+V+ S+ I E+Y S ++ +R +V R LRLV G ++ ++ ++ ++ L
Sbjct: 191 IVVIGFASM----IFEEYLKSGFDVKALRAFRVLRPLRLVSGVPSLQVVMNSIVKAMLPL 246
Query: 1666 FNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYN 1701
F+I LL+ V+ I+AI G+ F + D++ N
Sbjct: 247 FHIALLVVFVIIIYAIIGVELFTGKLHQTCYDNITN 282
Score = 62.9 bits (146), Expect = 9e-08
Identities = 33/100 (33%), Positives = 60/100 (60%), Gaps = 6/100 (6%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+ LR+FK+ + W +L+ L+ + ++ ++G+L +L + I IF+++GMQ+FG +
Sbjct: 592 LRCVRLLRIFKVTRYWESLSNLVQSLVNSIKSIGSLLLLLSLFILIFSLLGMQIFGGRF- 650
Query: 887 DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMW 925
+ ++ P PR NF F S + VF++L GE W M+
Sbjct: 651 NLDEQAP----PRTNFDSFWRSLITVFQILTGEDWNAVMY 686
Score = 56.4 bits (130), Expect = 7e-06
Identities = 39/167 (23%), Positives = 80/167 (47%), Gaps = 17/167 (10%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMP-------TTPTVESTEVIFTGIYTFESA 182
+RR I+ F +I + +N +++ + T ++ F G++TFE
Sbjct: 486 LRRQCRGIVKSQTFYWMVIIAVFLNSLVLAVEHYDQPDYITMFLDRANYFFLGLFTFEML 545
Query: 183 VKVMARGFILQPFTYLRDAWNWLDFVVI--ALAYVTMGIDLG----NLAALRTFRVLRAL 236
+K+ G + YL +N D +V+ +L V + + G ++ LR R+LR
Sbjct: 546 LKIYCLGI----YGYLNSLFNRFDCLVVLSSLLEVAITVPTGWPPIGISVLRCVRLLRIF 601
Query: 237 KTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
K L +V +++ S+K++ +++L + +F+L+G+QI+ G
Sbjct: 602 KVTRYWESLSNLVQSLVNSIKSIGSLLLLLSLFILIFSLLGMQIFGG 648
Score = 52.0 bits (119), Expect = 2e-04
Identities = 33/115 (28%), Positives = 63/115 (54%), Gaps = 10/115 (8%)
Query: 173 FTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVI--ALAYVTMG---IDLG-NLAA 226
FT ++ E +K+MA Y RD WN DFV++ ++A + +G D G +
Sbjct: 1228 FTAVFLLECVLKLMA----FNAKNYFRDPWNIFDFVIVVGSIADIIIGEISKDGGIKVNF 1283
Query: 227 LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
R FR LR +K ++ G++T++ ++S + L V +L + ++A++G+Q++
Sbjct: 1284 FRLFRALRLVKLLSQGDGIRTLLWTFMKSFQALPFVGLLILLLFFIYAVIGMQVF 1338
Score = 44.0 bits (99), Expect = 0.042
Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 5/104 (4%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LR+ KL + L+ ++ AL + ++ ++ FI+AV+GMQ+FG +D
Sbjct: 1290 LRLVKLLSQGDGIRTLLWTFMKSFQALPFVGLLILLLFFIYAVIGMQVFGTIRLDSGTVI 1349
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSC 935
+ NF F + +++FR GE W + M C+ V C
Sbjct: 1350 NSNN----NFQTFPQALIVLFRSATGENWQQIMMACVNSESVKC 1389
Score = 37.1 bits (82), Expect = 4.9
Identities = 16/57 (28%), Positives = 36/57 (63%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
KAL++ LR +L P+L ++++ + + M L ++ ++ +I I+A++G++LF
Sbjct: 212 KALRAFRVLRPLRLVSGVPSLQVVMNSIVKAMLPLFHIALLVVFVIIIYAIIGVELF 268
>UniRef50_Q869H4 Cluster: Voltage-dependent L-type calcium channel
alpha-1 subunit isoform b; n=2; Lymnaea stagnalis|Rep:
Voltage-dependent L-type calcium channel alpha-1 subunit
isoform b - Lymnaea stagnalis (Great pond snail)
Length = 2186
Score = 318 bits (781), Expect = 1e-84
Identities = 214/721 (29%), Positives = 376/721 (52%), Gaps = 51/721 (7%)
Query: 1169 DEDVVDDTPADCCPEQCYQKFPFLAGDDDSPF-----WQGWGTLRLKTFKLIENTYFETA 1223
+E+ D+TP+ P + + PF + R+ K+ ++YF
Sbjct: 899 EEEDEDETPSSARPRRMSELHISSRVKPIPPFSSLFIFSATNKFRIICHKICNHSYFGNV 958
Query: 1224 VITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQ----KY 1279
V+ IL+SS LA ED P Q IL D FT +F IE++IK + G +
Sbjct: 959 VLACILISSAMLAAEDPLRNESPRNQ-ILNKFDYFFTSVFTIEIIIKIITYGLMLHKGSF 1017
Query: 1280 FTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNA 1339
+ + LD ++V VSLI+F I K +R LR LRPLRA++R +G++ VV
Sbjct: 1018 CRSLFSILDLVVVAVSLISFPL---DNQAISVVKILRVLRVLRPLRAINRAKGLKHVVQC 1074
Query: 1340 LVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTT----LSHEIIPDK--- 1392
++ A+ +I+N++LV + +F++MGVQLF GK+ C D + T + I D
Sbjct: 1075 VIVALRTIYNIMLVTFLLNFMFSVMGVQLFKGKFSMCTDESKLTEDECQGNFITYDDGKF 1134
Query: 1393 NACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIY 1452
N+ +E W+ + NFD V L LF V+TF+GW ++ +IDS G+ PI+ +
Sbjct: 1135 NSPNIEERKWKKNDFNFDDVSNGMLTLFTVSTFEGWPGLLYKSIDSHAEGKGPIQNSKPA 1194
Query: 1453 MYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSK 1512
+ ++ +N+F+G +I F + ++ + E + ++Q+K K+
Sbjct: 1195 VAVFYFIFIIVIAFFMMNIFVGFVIVTFQNEGEQEYKNCE--LDKNQRKCIEFALKV--- 1249
Query: 1513 KPLKA-IPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYL 1571
KP++ IP+ RW Q ++ VT + F+ I + I +N + + + ++ QS ++S LDYL
Sbjct: 1250 KPIRRYIPKARW--QYKIWWFVTSQAFEYGIFVLIMINTVALAMKYHGQSASYSDALDYL 1307
Query: 1572 NMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSLVLSDIIE-KYFVSPTL 1629
N+IF +F+ E +LK+ A R+ +YF + WN+FDF++V+ S + ++ +++ K F+S
Sbjct: 1308 NIIFTGVFTVEFVLKLAAFRFKNYFGDAWNVFDFIIVLGSFIDIIYAEVNPGKAFISINF 1367
Query: 1630 LRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMH 1689
R+ RV R+++L+ +GIRTLL+ S AL + LL+ ++ FI+A+ GM F
Sbjct: 1368 FRLFRVM---RLIKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGR 1424
Query: 1690 VK--DKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEE--ECDLPDNERG--- 1742
+K + NF+TF ++++LF+ +T W ++ ++ +CD E G
Sbjct: 1425 IKLDYNTQIHPNNNFQTFPHAVLVLFRSATGESWQEIMLACSDKTAVKCDPAVIEHGVNV 1484
Query: 1743 ---SPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMY 1799
CG+ + ++ Y++ SFLI IN+++AVI++N+ T D L D +
Sbjct: 1485 TDAEANRCGNDFAYVYFISFYILCSFLI-INLFVAVIMDNFDYLTRD-WSILGPHHLDEF 1542
Query: 1800 YEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHK--PNKY---KIISMDIPI-CRGDMM 1853
+W +DP+ I++ + L + PPL K P++ +++SM++P+ G +M
Sbjct: 1543 VRLWSEYDPEAKGRIKHLDVVTLLRKISPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVM 1602
Query: 1854 F 1854
F
Sbjct: 1603 F 1603
Score = 138 bits (333), Expect = 2e-30
Identities = 88/313 (28%), Positives = 160/313 (51%), Gaps = 50/313 (15%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTT-PTVESTEV------- 171
AL+ L NPIR+ I + + F ++ TI NC+ + + T P +S EV
Sbjct: 126 ALFCLTLKNPIRKFCIQVAEYKAFEFLVLITIFANCVALAIYTPYPMSDSNEVNSALDRI 185
Query: 172 --IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLG-----NL 224
+F I+ E +K++A GF++ YLR+ WN LDF ++ + ++ + ++
Sbjct: 186 EYVFLVIFLLEGILKIIAYGFVMHQGAYLRNGWNALDFTIVVIGIISSILSFVQEKGFDV 245
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
ALR FRVLR L+ V+ P L+ ++ +++ ++ L + +L +F + ++A++GL+++ G
Sbjct: 246 KALRAFRVLRPLRLVSRAPSLQVVLNSIVRAMVPLLHIALLVIFVIIIYAIIGLELFYGK 305
Query: 285 LTQKCVKVFPEDGSWGNLTDENWE-RFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCL 343
L C K+ N T+ + + R C G+G + G+C G+
Sbjct: 306 LHNACYKI--------NSTEFSGDPRIC-------GQGYSCDDIASGGEKGECREGW--- 347
Query: 344 QGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWEN-LYQ-----------LFFVVIIFLG 391
PNYG T+FD FG A L+ F+ +T + W LY ++F+ +I +G
Sbjct: 348 ----EGPNYGITNFDNFGLAMLTVFQCITMEGWTTVLYDVNNALGNEWPWIYFISLIIIG 403
Query: 392 SFYLVNLILAIVA 404
SF+++NL+L +++
Sbjct: 404 SFFVLNLVLGVLS 416
Score = 110 bits (265), Expect = 3e-22
Identities = 84/301 (27%), Positives = 149/301 (49%), Gaps = 30/301 (9%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVH-LPHRPILQDILYYMDRIFTVIFFI 1265
+R ++ E FE V+ I + +ALA+ + + + L ++ +F VIF +
Sbjct: 136 IRKFCIQVAEYKAFEFLVLITIFANCVALAIYTPYPMSDSNEVNSALDRIEYVFLVIFLL 195
Query: 1266 EMLIKWLALGFQK----YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRAL 1321
E ++K +A GF Y N W LDF IV++ +I+ + + G K +R R L
Sbjct: 196 EGILKIIAYGFVMHQGAYLRNGWNALDFTIVVIGIISSILSFVQEKGFDV-KALRAFRVL 254
Query: 1322 RPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGK-YFKCVDMN 1380
RPLR +SR ++VV+N++V+A+ + ++ L+ + +I+AI+G++LF GK + C +N
Sbjct: 255 RPLRLVSRAPSLQVVLNSIVRAMVPLLHIALLVIFVIIIYAIIGLELFYGKLHNACYKIN 314
Query: 1381 HTTLSHE--IIPDKNAC-----------TLENYTWENSPM-NFDHVGKAYLCLFQVATFK 1426
T S + I +C E + N + NFD+ G A L +FQ T +
Sbjct: 315 STEFSGDPRICGQGYSCDDIASGGEKGECREGWEGPNYGITNFDNFGLAMLTVFQCITME 374
Query: 1427 GWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
GW ++ D + +G N + ++Y LNL +GV+ F+++++K
Sbjct: 375 GWTTVLYDV--NNALG-------NEWPWIYFISLIIIGSFFVLNLVLGVLSGEFSKEREK 425
Query: 1487 A 1487
A
Sbjct: 426 A 426
Score = 102 bits (245), Expect = 9e-20
Identities = 73/255 (28%), Positives = 130/255 (50%), Gaps = 18/255 (7%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR 1591
IV + F +++ + LN + +T +HY+Q N+ F+V+F+ E L+K+++L
Sbjct: 521 IVKSQAFYWGVIVLVFLNTVVLTSEHYKQPVWLDDFQAIANLFFVVLFTMEMLVKMYSLG 580
Query: 1592 YH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
+ YFV +N FD VV+ SIL ++L F P + V+R A++ RV + +
Sbjct: 581 FQGYFVSLFNRFDSFVVVCSILEVILQ--YTNVF-PPLGISVLRCARLLRVFKATRYWSS 637
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF-MHVKDKGGLDDVYNFKTFVQSM 1709
+R L+ +L S+ ++ ++ LLLFL + IFA+ GM F G NF TF S+
Sbjct: 638 LRNLVASLLNSMRSIASLLLLLFLFIVIFALLGMQLFGGKFNFPQGEKPRSNFDTFWPSL 697
Query: 1710 ILLFQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIV 1768
+ +FQ+ T W+ V+ DGI R G + Y + ++ I+
Sbjct: 698 LTVFQILTGEDWNAVMYDGI------------RAYDGVKFPGILVCLYFVVLFIVGNYIL 745
Query: 1769 INMYIAVILENYSQA 1783
+N+++A+ ++N + A
Sbjct: 746 LNVFLAIAVDNLADA 760
Score = 93.9 bits (223), Expect = 4e-17
Identities = 75/305 (24%), Positives = 138/305 (45%), Gaps = 35/305 (11%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
+++++ F VI ++ L+++ L E H L D + F V+F +EML+K
Sbjct: 520 RIVKSQAFYWGVIVLVFLNTVVLTSE--HYKQPVWLDDFQAIANLFFVVLFTMEMLVKMY 577
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG 1332
+LGFQ YF + + D +V+ S++ + +R R LR +A
Sbjct: 578 SLGFQGYFVSLFNRFDSFVVVCSILEVILQYTNVFPPLGISVLRCARLLRVFKATRYWSS 637
Query: 1333 MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDK 1392
+R +V +L+ ++ SI ++LL+ +F +IFA++G+QLF GK+
Sbjct: 638 LRNLVASLLNSMRSIASLLLLLFLFIVIFALLGMQLFGGKF------------------- 678
Query: 1393 NACTLENYTWENSP-MNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNI 1451
N+ P NFD + L +FQ+ T + W +M D I + + + P I
Sbjct: 679 ------NFPQGEKPRSNFDTFWPSLLTVFQILTGEDWNAVMYDGIRAYDGVKFP----GI 728
Query: 1452 YMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGS 1511
+ LY LN+F+ + +DN + + E E++K+ ++++ S
Sbjct: 729 LVCLYFVVLFIVGNYILLNVFLAIAVDNLADAQSLTEIEEE---KEEEKERTRSLRRSKS 785
Query: 1512 KKPLK 1516
+ P K
Sbjct: 786 RSPNK 790
Score = 79.0 bits (186), Expect = 1e-12
Identities = 50/147 (34%), Positives = 80/147 (54%), Gaps = 12/147 (8%)
Query: 782 LEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMD-KALKSGNYLRVFKLAK 840
L FQ Y L F+ F + F+ +C ++ + L + N+ + L+ LRVFK +
Sbjct: 579 LGFQGYFVSL-FNRF-DSFVVVCSILEVI---LQYTNVFPPLGISVLRCARLLRVFKATR 633
Query: 841 SWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRW 900
W +L L++ + +M ++ +L +L + I IFA++GMQLFG + FP G+ PR
Sbjct: 634 YWSSLRNLVASLLNSMRSIASLLLLLFLFIVIFALLGMQLFGGKF-----NFPQGEKPRS 688
Query: 901 NFTDFMHSFMIVFRVLCGE-WIESMWD 926
NF F S + VF++L GE W M+D
Sbjct: 689 NFDTFWPSLLTVFQILTGEDWNAVMYD 715
Score = 78.2 bits (184), Expect = 2e-12
Identities = 50/165 (30%), Positives = 90/165 (54%), Gaps = 12/165 (7%)
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTL-DHYQQSET--FSAVLDYLNMIFIVIFSSECLLKI 1587
++ K F+ ++++ I N + + + Y S++ ++ LD + +F+VIF E +LKI
Sbjct: 142 QVAEYKAFEFLVLITIFANCVALAIYTPYPMSDSNEVNSALDRIEYVFLVIFLLEGILKI 201
Query: 1588 FALRY--H---YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVL 1642
A + H Y WN DF +V+ I+S +LS + EK F ++ +R +V R L
Sbjct: 202 IAYGFVMHQGAYLRNGWNALDFTIVVIGIISSILSFVQEKGFD----VKALRAFRVLRPL 257
Query: 1643 RLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
RLV A ++ +L ++ ++ L +I LL+ V+ I+AI G+ F
Sbjct: 258 RLVSRAPSLQVVLNSIVRAMVPLLHIALLVIFVIIIYAIIGLELF 302
Score = 77.0 bits (181), Expect = 5e-12
Identities = 43/176 (24%), Positives = 91/176 (51%), Gaps = 11/176 (6%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM--------PTTPTVESTE 170
++L+I N R + I H F ++ IL++ ++ P + +
Sbjct: 931 SSLFIFSATNKFRIICHKICNHSYFGNVVLACILISSAMLAAEDPLRNESPRNQILNKFD 990
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID---LGNLAAL 227
FT ++T E +K++ G +L ++ R ++ LD VV+A++ ++ +D + + L
Sbjct: 991 YFFTSVFTIEIIIKIITYGLMLHKGSFCRSLFSILDLVVVAVSLISFPLDNQAISVVKIL 1050
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
R RVLR L+ + GLK +V VI +++ + +++++T +F++MG+Q++ G
Sbjct: 1051 RVLRVLRPLRAINRAKGLKHVVQCVIVALRTIYNIMLVTFLLNFMFSVMGVQLFKG 1106
Score = 59.3 bits (137), Expect = 1e-06
Identities = 42/168 (25%), Positives = 81/168 (48%), Gaps = 18/168 (10%)
Query: 143 FSLFIITTILVNCILMIMPT-------TPTVESTEVIFTGIYTFESAVKVMARGFILQPF 195
F I I++N + + M + ++ +IFTG++T E +K+ A F
Sbjct: 1274 FEYGIFVLIMINTVALAMKYHGQSASYSDALDYLNIIFTGVFTVEFVLKLAAFRFK---- 1329
Query: 196 TYLRDAWNWLDFVV-------IALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTI 248
Y DAWN DF++ I A V G ++ R FRV+R +K ++ G++T+
Sbjct: 1330 NYFGDAWNVFDFIIVLGSFIDIIYAEVNPGKAFISINFFRLFRVMRLIKLLSRGEGIRTL 1389
Query: 249 VGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPED 296
+ I+S + L V +L + ++A++G+Q++ + ++ P +
Sbjct: 1390 LWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGRIKLDYNTQIHPNN 1437
Score = 54.8 bits (126), Expect = 2e-05
Identities = 33/106 (31%), Positives = 54/106 (50%), Gaps = 5/106 (4%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
+R+ KL + L+ ++ AL + ++ ++ FI+AV+GMQ+FG+ +DY +
Sbjct: 1374 MRLIKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGRIKLDYNTQI 1433
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSCIP 937
P NF F H+ +++FR GE W E M C V C P
Sbjct: 1434 H----PNNNFQTFPHAVLVLFRSATGESWQEIMLACSDKTAVKCDP 1475
Score = 48.4 bits (110), Expect = 0.002
Identities = 33/120 (27%), Positives = 62/120 (51%), Gaps = 12/120 (10%)
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLD-FVVIA------LAYVTMGIDLGN 223
+ F ++T E VK+ + GF Y +N D FVV+ L Y + LG
Sbjct: 562 LFFVVLFTMEMLVKMYSLGFQ----GYFVSLFNRFDSFVVVCSILEVILQYTNVFPPLG- 616
Query: 224 LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
++ LR R+LR K L+ +V +++ S++++ +++L + +FAL+G+Q++ G
Sbjct: 617 ISVLRCARLLRVFKATRYWSSLRNLVASLLNSMRSIASLLLLLFLFIVIFALLGMQLFGG 676
Score = 39.9 bits (89), Expect = 0.69
Identities = 22/78 (28%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 805 IVVNTLFMALDHHNMDKDMD-KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLT 863
IVV + ++ +K D KAL++ LR +L P+L ++++ + R M L ++
Sbjct: 225 IVVIGIISSILSFVQEKGFDVKALRAFRVLRPLRLVSRAPSLQVVLNSIVRAMVPLLHIA 284
Query: 864 FVLCIIIFIFAVMGMQLF 881
++ +I I+A++G++LF
Sbjct: 285 LLVIFVIIIYAIIGLELF 302
>UniRef50_A0BV23 Cluster: Chromosome undetermined scaffold_13, whole
genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_13, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 1565
Score = 317 bits (779), Expect = 2e-84
Identities = 192/641 (29%), Positives = 342/641 (53%), Gaps = 38/641 (5%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+R++ KLI + YFE ++T+I++SS+ LAL+D I +++ D I T +F E
Sbjct: 817 IRIRVSKLINHKYFEFFILTIIIISSILLALDDPLSSSNNITLNVI---DEIITALFICE 873
Query: 1267 MLIKWLALGF-----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRAL 1321
+K ++ GF Y + LD ++++ S + F + A K +R +R L
Sbjct: 874 AALKIISKGFILNGPDSYIRSPGNILDLVVIIFSSLAFDESQ--AQTFSKIKILRVIRVL 931
Query: 1322 RPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNH 1381
RPLR + R + +++ +NAL ++ + N+ LVCLIF+L+F I GV F G Y+ C D+
Sbjct: 932 RPLRLIVRNEDLKMSINALFNSLSQMMNIALVCLIFFLLFGIFGVTQFKGAYYHC-DV-- 988
Query: 1382 TTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREV 1441
E + DK C + +W N NFD+V A + LF ++T +GWI +M+D IDSR +
Sbjct: 989 -----EDVNDKLECFDKGGSWSNKNFNFDNVLNAMITLFVISTTEGWINLMSDGIDSRGI 1043
Query: 1442 GRQPIRETNIYMY-LYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQK 1500
P +E N Y + LY +NLF GVI++ F +K + ++ ++ +
Sbjct: 1044 DLNP-QENNAYAWALYFVFFIIVGSFFIINLFAGVIVEAFQSEKDRLSQMRDL--SKQEL 1100
Query: 1501 KYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQ 1560
++Y +K+ S P++ + + + +I++ KF++ I+ I LN M + + +
Sbjct: 1101 EWYEIQQKIYSSVPIEKFKISKHKTVRQLNDIISSDKFEIFILSVIILNTCVMMIQYLRS 1160
Query: 1561 SETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVL--SD 1618
+ + + LN IF+ IFS E +LK+ R YF WN+FDF VV+ +IL ++L S+
Sbjct: 1161 PQELTDAIQILNWIFLAIFSIEAILKLIVYRKFYFTSGWNVFDFTVVLLTILGVILEQSN 1220
Query: 1619 IIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFI 1678
++ + ++LR R+ RVLRL+K AK +R + ++LP L ++ LL +++FI
Sbjct: 1221 VLSNVGTATSILRTFRIF---RVLRLIKSAKNLRIIFGTFLVTLPGLVSVGGLLGIMLFI 1277
Query: 1679 FAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEE----C 1734
FA+ M+ F +VK G+ NF +F S+ LF+ ST W+ V+ + C
Sbjct: 1278 FAVVFMNLFPYVKRGEGVTGNSNFSSFGVSLFTLFKCSTGEDWNLVMMDTARTAQPNDIC 1337
Query: 1735 -DLPD----NERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQE 1789
D D E G G CG+ GI ++ +++I LI++N+++A+I+E + +++
Sbjct: 1338 FDFNDYANYAEYGFMG-CGNVG-GILLMIIFMIIVSLIMLNLFVAIIIEGFQNTSKEENA 1395
Query: 1790 GLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPL 1830
+ D + + + W+ +D + + +++ + F+ L PL
Sbjct: 1396 PIKKLDVENFQQQWKDYDKNATGFMQCKYFTQFMIALPQPL 1436
Score = 149 bits (360), Expect = 1e-33
Identities = 98/312 (31%), Positives = 167/312 (53%), Gaps = 37/312 (11%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT---------TPT--VES 168
+L + D N IR AI+++ F FIIT I +N IL+ P +S
Sbjct: 60 SLNLFDAENKIRLWAIWMIEWIWFDRFIITVIFLNSILLATQDYSWRETDSEAPNSWTDS 119
Query: 169 TEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALR 228
E IFT I+ E +K++A GF+L TYLRD WN++DF+V+ +++ I ++A+R
Sbjct: 120 FEYIFTAIFIIEFLLKMIAMGFLLDKQTYLRDGWNFIDFIVVITGIISLFIS-ARVSAIR 178
Query: 229 TFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQK 288
R++R L+++ + +K ++ +++S+ L +V+I +F + +F ++GLQI+MG L +
Sbjct: 179 IIRIMRPLRSINSLKQMKVLIITLLDSLPALGNVVIFLLFIIILFGILGLQIFMGALENR 238
Query: 289 C-VKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFG 347
C + P W N+ + CQ+ +N G Y CGN + + +
Sbjct: 239 CRMTEHPVGNEW---VASNYTKLCQDSSNC--PDGTY--CGNPNTYNLPQQ-----ESDD 286
Query: 348 PNPNYGYTSFDTFGWAFLSAFRLMTQDYWENL---YQ---------LFFVVIIFLGSFYL 395
NYGYT+F+ A + F+ +T + W L YQ ++F+++IFLGSF++
Sbjct: 287 ETFNYGYTNFNNIISATFTIFQALTTEGWTKLIFIYQEALSTAIVYIYFLLLIFLGSFFV 346
Query: 396 VNLILAIVAMSY 407
VNLILA++ S+
Sbjct: 347 VNLILAVINDSF 358
Score = 107 bits (258), Expect = 2e-21
Identities = 72/286 (25%), Positives = 142/286 (49%), Gaps = 30/286 (10%)
Query: 1511 SKKPLKAIPRPRWRP-QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLD 1569
SKK + + ++R Q I+ I+ +K F I I LN +T++LD Y ++T S +LD
Sbjct: 473 SKKRSFKLKQSKFRQFQLILIVIIENKYFLAFITSIIILNTITLSLDRYPITKTESDILD 532
Query: 1570 YLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTL 1629
N +F VIF+ E LK+ A +Y + N+FD V+V+ S++ +LS S +
Sbjct: 533 IANQVFTVIFTIEMTLKLIAFDTNYLKDSMNIFDAVIVILSLIEWILS--------SFSA 584
Query: 1630 LRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMH 1689
++ R ++ R+ +L + R LL A+A ++ + +LL L M + A+ GM F +
Sbjct: 585 IQAFRTLRLFRLFKLARTWSSFRKLLSAIAATVGGIAYFIILLLLFMSVAALLGMELFAY 644
Query: 1690 VKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGS 1749
YNF ++ SM+++F + T+ W+ + + + E P
Sbjct: 645 KTPYR-----YNFNNYLSSMLVVFMLLTNESWNTIAYTFMYDLESIYP------------ 687
Query: 1750 ATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDD 1795
+ Y + ++ I++ ++IA+++ N+ +A + + + +++
Sbjct: 688 ----VIYFVVVIIFGNFILLKLFIAILINNFHEANVEQSQSIEENN 729
Score = 95.5 bits (227), Expect = 1e-17
Identities = 83/306 (27%), Positives = 148/306 (48%), Gaps = 49/306 (16%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYY--MDRIFTVIFF 1264
+RL +IE +F+ +IT+I L+S+ LA +D + + IFT IF
Sbjct: 70 IRLWAIWMIEWIWFDRFIITVIFLNSILLATQDYSWRETDSEAPNSWTDSFEYIFTAIFI 129
Query: 1265 IEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLIN-FVAALCGAGGIQAFKTMRTLR 1319
IE L+K +A+GF Q Y + W ++DFI+V+ +I+ F++A A +R +R
Sbjct: 130 IEFLLKMIAMGFLLDKQTYLRDGWNFIDFIVVITGIISLFISARVSA--------IRIIR 181
Query: 1320 ALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKC-- 1376
+RPLR+++ ++ M+V++ L+ ++P++ NV++ L ++F I+G+Q+F G +C
Sbjct: 182 IMRPLRSINSLKQMKVLIITLLDSLPALGNVVIFLLFIIILFGILGLQIFMGALENRCRM 241
Query: 1377 ---------VDMNHTTLSHEI--IPDKNAC-----------TLENYTWENSPMNFDHVGK 1414
V N+T L + PD C ++ T+ NF+++
Sbjct: 242 TEHPVGNEWVASNYTKLCQDSSNCPDGTYCGNPNTYNLPQQESDDETFNYGYTNFNNIIS 301
Query: 1415 AYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIG 1474
A +FQ T +GW +++ Q T I +Y+Y +NL +
Sbjct: 302 ATFTIFQALTTEGWTKLI--------FIYQEALSTAI-VYIYFLLLIFLGSFFVVNLILA 352
Query: 1475 VIIDNF 1480
VI D+F
Sbjct: 353 VINDSF 358
Score = 81.4 bits (192), Expect = 2e-13
Identities = 51/159 (32%), Positives = 90/159 (56%), Gaps = 8/159 (5%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
+IEN YF + ++I+L+++ L+L+ P DIL +++FTVIF IEM +K +A
Sbjct: 495 IIENKYFLAFITSIIILNTITLSLD--RYPITKTESDILDIANQVFTVIFTIEMTLKLIA 552
Query: 1274 LGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGM 1333
Y ++ D +IV++SLI ++ L IQAF+T+R R + R S
Sbjct: 553 FD-TNYLKDSMNIFDAVIVILSLIEWI--LSSFSAIQAFRTLRLFRLFKLARTWS---SF 606
Query: 1334 RVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGK 1372
R +++A+ + I +++ L+F + A++G++LFA K
Sbjct: 607 RKLLSAIAATVGGIAYFIILLLLFMSVAALLGMELFAYK 645
Score = 78.2 bits (184), Expect = 2e-12
Identities = 55/200 (27%), Positives = 100/200 (50%), Gaps = 18/200 (9%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM--PTTP----TVESTEVIF 173
+L+I P N IR ++ H F FI+T I+++ IL+ + P + T+ + I
Sbjct: 807 SLFIFPPQNKIRIRVSKLINHKYFEFFILTIIIISSILLALDDPLSSSNNITLNVIDEII 866
Query: 174 TGIYTFESAVKVMARGFILQ-PFTYLRDAWNWLDFVVI---ALAY-VTMGIDLGNLAALR 228
T ++ E+A+K++++GFIL P +Y+R N LD VVI +LA+ + + LR
Sbjct: 867 TALFICEAALKIISKGFILNGPDSYIRSPGNILDLVVIIFSSLAFDESQAQTFSKIKILR 926
Query: 229 TFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVL--- 285
RVLR L+ + LK + A+ S+ + ++ ++ + +F + G+ + G
Sbjct: 927 VIRVLRPLRLIVRNEDLKMSINALFNSLSQMMNIALVCLIFFLLFGIFGVTQFKGAYYHC 986
Query: 286 ----TQKCVKVFPEDGSWGN 301
++ F + GSW N
Sbjct: 987 DVEDVNDKLECFDKGGSWSN 1006
Score = 75.8 bits (178), Expect = 1e-11
Identities = 50/160 (31%), Positives = 76/160 (47%), Gaps = 19/160 (11%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAV----LDYLNMIFIVIFSSECLLKIFALRY- 1592
FD I+ I LN + + Y ET S D IF IF E LLK+ A+ +
Sbjct: 83 FDRFIITVIFLNSILLATQDYSWRETDSEAPNSWTDSFEYIFTAIFIIEFLLKMIAMGFL 142
Query: 1593 ----HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGA 1648
Y + WN DF+VV+ I+SL +S + +R+ ++ R LR +
Sbjct: 143 LDKQTYLRDGWNFIDFIVVITGIISLFISARVS----------AIRIIRIMRPLRSINSL 192
Query: 1649 KGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
K ++ L+ L SLPAL N+ + L ++ +F I G+ FM
Sbjct: 193 KQMKVLIITLLDSLPALGNVVIFLLFIIILFGILGLQIFM 232
Score = 59.7 bits (138), Expect = 8e-07
Identities = 42/163 (25%), Positives = 80/163 (49%), Gaps = 13/163 (7%)
Query: 127 FNPIRRVAIYILVHPLFSLFIITTILVNCILMIM---PTTPT----VESTEVIFTGIYTF 179
F + + I I+ + F FI + I++N I + + P T T ++ +FT I+T
Sbjct: 485 FRQFQLILIVIIENKYFLAFITSIIILNTITLSLDRYPITKTESDILDIANQVFTVIFTI 544
Query: 180 ESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID-LGNLAALRTFRVLRALKT 238
E +K++A YL+D+ N D V++ L+ + + + A RT R+ R K
Sbjct: 545 EMTLKLIAFDT-----NYLKDSMNIFDAVIVILSLIEWILSSFSAIQAFRTLRLFRLFKL 599
Query: 239 VAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+ ++ A+ +V + IIL + +SV AL+G++++
Sbjct: 600 ARTWSSFRKLLSAIAATVGGIAYFIILLLLFMSVAALLGMELF 642
Score = 54.4 bits (125), Expect = 3e-05
Identities = 40/154 (25%), Positives = 76/154 (49%), Gaps = 20/154 (12%)
Query: 143 FSLFIITTILVN-CILMIMPTTPTVESTEVI------FTGIYTFESAVKVMARGFILQPF 195
F +FI++ I++N C++MI E T+ I F I++ E+ +K++ + + F
Sbjct: 1138 FEIFILSVIILNTCVMMIQYLRSPQELTDAIQILNWIFLAIFSIEAILKLI----VYRKF 1193
Query: 196 TYLRDAWNWLDFVVIALAYVTMGIDLGNLAA--------LRTFRVLRALKTVAIVPGLKT 247
Y WN DF V+ L + + ++ N+ + LRTFR+ R L+ + L+
Sbjct: 1194 -YFTSGWNVFDFTVVLLTILGVILEQSNVLSNVGTATSILRTFRIFRVLRLIKSAKNLRI 1252
Query: 248 IVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
I G + ++ L V L L +FA++ + ++
Sbjct: 1253 IFGTFLVTLPGLVSVGGLLGIMLFIFAVVFMNLF 1286
Score = 49.2 bits (112), Expect = 0.001
Identities = 26/95 (27%), Positives = 52/95 (54%), Gaps = 11/95 (11%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKN 884
+A ++ R+FKLA++W + L+S + T+G + +L + + + A++GM+LF
Sbjct: 586 QAFRTLRLFRLFKLARTWSSFRKLLSAIAATVGGIAYFIILLLLFMSVAALLGMELFA-- 643
Query: 885 YVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE 919
Y + R+NF +++ S ++VF +L E
Sbjct: 644 ---YKTPY------RYNFNNYLSSMLVVFMLLTNE 669
Score = 39.5 bits (88), Expect = 0.91
Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 10/126 (7%)
Query: 805 IVVNTLFMALDHHNMDKDMDKA---LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGN 861
+++ L + L+ N+ ++ A L++ RV +L KS L ++ T+ L +
Sbjct: 1207 VLLTILGVILEQSNVLSNVGTATSILRTFRIFRVLRLIKSAKNLRIIFGTFLVTLPGLVS 1266
Query: 862 LTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-W 920
+ +L I++FIFAV+ M LF YV R +G NF+ F S +F+ GE W
Sbjct: 1267 VGGLLGIMLFIFAVVFMNLF-----PYVKR-GEGVTGNSNFSSFGVSLFTLFKCSTGEDW 1320
Query: 921 IESMWD 926
M D
Sbjct: 1321 NLVMMD 1326
>UniRef50_O00555 Cluster: Voltage-dependent P/Q-type calcium channel
subunit alpha-1A; n=63; Euteleostomi|Rep:
Voltage-dependent P/Q-type calcium channel subunit
alpha-1A - Homo sapiens (Human)
Length = 2505
Score = 315 bits (774), Expect = 7e-84
Identities = 207/705 (29%), Positives = 361/705 (51%), Gaps = 43/705 (6%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
LR ++ YFE ++ +I +SS+ALA ED P+ P ++L Y D +FT +F E
Sbjct: 1233 LRRLCHYILNLRYFEMCILMVIAMSSIALAAEDPVQPNAP-RNNVLRYFDYVFTGVFTFE 1291
Query: 1267 MLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAG-GIQAFKTMRTLRAL 1321
M+IK + LG YF + W LDFI+V +L+ F G I K++R LR L
Sbjct: 1292 MVIKMIDLGLVLHQGAYFRDLWNILDFIVVSGALVAFAFTGNSKGKDINTIKSLRVLRVL 1351
Query: 1322 RPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD--- 1378
RPL+ + R+ ++ V + +V ++ ++FN+L+V ++F IFA++ VQLF GK+F C D
Sbjct: 1352 RPLKTIKRLPKLKAVFDCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESK 1411
Query: 1379 -MNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAID 1437
++ +KN + W+ ++D+V A L LF V+T +GW Q++ ++D
Sbjct: 1412 EFEKDCRGKYLLYEKNEVKARDREWKKYEFHYDNVLWALLTLFTVSTGEGWPQVLKHSVD 1471
Query: 1438 SREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTE 1497
+ + P + M ++ +N+F+ +II F EQ K +E + E
Sbjct: 1472 ATFENQGPSPGYRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDK---MMEEYSLE 1528
Query: 1498 DQKKYYNAMKKMGSKKPL-KAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLD 1556
++ + S KPL + +P+ + Q +++ V F+ IM I LN + + +
Sbjct: 1529 KNER--ACIDFAISAKPLTRHMPQNKQSFQYRMWQFVVSPPFEYTIMAMIALNTIVLMMK 1586
Query: 1557 HYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR-YHYFVEPWNLFDFVVVMFSILSLV 1615
Y S + L N++F +FS EC+LK+ A +YF + WN+FDFV V+ SI ++
Sbjct: 1587 FYGASVAYENALRVFNIVFTSLFSLECVLKVMAFGILNYFRDAWNIFDFVTVLGSITDIL 1646
Query: 1616 LSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLV 1675
+++ F++ + LR+ R A R+++L++ IR LL+ S AL +CLL+ ++
Sbjct: 1647 VTE-FGNNFINLSFLRLFRAA---RLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAML 1702
Query: 1676 MFIFAIFGMSFF----MHVKDKGGLDDVY------NFKTFVQSMILLFQMSTSAGWDGVL 1725
FI+AI GM F + V+D+ +D + NF+TF Q+++LLF+ +T W ++
Sbjct: 1703 FFIYAIIGMQVFGNIGIDVEDEDSDEDEFQITEHNNFRTFFQALMLLFRSATGEAWHNIM 1762
Query: 1726 DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATE 1785
++ + CD N CG+ Y +S++ + +++N+++AVI++N+ T
Sbjct: 1763 LSCLSGKPCD--KNSGILTRECGN-EFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTR 1819
Query: 1786 DVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHK--PNK--YK-I 1840
D L D Y +W +DP + Y + L + PPL + K P + YK +
Sbjct: 1820 D-SSILGPHHLDEYVRVWAEYDPAAWGRMPYLDMYQMLRHMSPPLGLGKKCPARVAYKRL 1878
Query: 1841 ISMDIPICRGDMMFCVDILDALTK---DFFARKGNPIEETGDLEV 1882
+ MD+P+ + + L AL + D KG ++ D E+
Sbjct: 1879 LRMDLPVADDNTVHFNSTLMALIRTALDIKIAKGGADKQQMDAEL 1923
Score = 138 bits (335), Expect = 1e-30
Identities = 92/312 (29%), Positives = 159/312 (50%), Gaps = 47/312 (15%)
Query: 116 SATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM----------PTTPT 165
+ +L++ N +R+ A I P F I+ TI+ NCI++ + P +
Sbjct: 73 TVNRSLFLFSEDNVVRKYAKKITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSER 132
Query: 166 VESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV-TMGIDLGNL 224
++ TE F GI+ FE+ +K++A GF +YLR+ WN +DFVV+ + T+G + +L
Sbjct: 133 LDDTEPYFIGIFCFEAGIKIIALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTEF-DL 191
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
LR RVLR LK V+ +P L+ ++ ++++++ L + +L F++ +FA++GL+ YMG
Sbjct: 192 RTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGK 251
Query: 285 LTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQ 344
C E+G TD+ +G CG A C G C Q
Sbjct: 252 FHTTCF----EEG-----TDDI-------------QGESPAPCGTEEPARTCPNGTKC-Q 288
Query: 345 GFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ------------LFFVVIIFLGS 392
+ PN G T FD +A L+ F+ +T + W +L L+F+ +I +GS
Sbjct: 289 PYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYNSNDASGNTWNWLYFIPLIIIGS 348
Query: 393 FYLVNLILAIVA 404
F+++NL+L +++
Sbjct: 349 FFMLNLVLGVLS 360
Score = 111 bits (266), Expect = 2e-22
Identities = 59/180 (32%), Positives = 103/180 (57%), Gaps = 15/180 (8%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILM-----IMPTTP---TVESTE 170
++++IL NP+RR+ YIL F + I+ I ++ I + + P P + +
Sbjct: 1222 SSMFILSTTNPLRRLCHYILNLRYFEMCILMVIAMSSIALAAEDPVQPNAPRNNVLRYFD 1281
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM-------GIDLGN 223
+FTG++TFE +K++ G +L Y RD WN LDF+V++ A V G D+
Sbjct: 1282 YVFTGVFTFEMVIKMIDLGLVLHQGAYFRDLWNILDFIVVSGALVAFAFTGNSKGKDINT 1341
Query: 224 LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
+ +LR RVLR LKT+ +P LK + V+ S+KN+ +++I+ M + +FA++ +Q++ G
Sbjct: 1342 IKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKG 1401
Score = 100 bits (240), Expect = 3e-19
Identities = 75/311 (24%), Positives = 138/311 (44%), Gaps = 32/311 (10%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+R ++++ F V++++ L++L +A+ VH L D LYY + IF +F E
Sbjct: 476 MRFYIRRMVKTQAFYWTVLSLVALNTLCVAI--VHYNQPEWLSDFLYYAEFIFLGLFMSE 533
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
M IK LG + YF +++ D +++ S+ + A+ G +R LR LR +
Sbjct: 534 MFIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVIWAVIKPGTSFGISVLRALRLLRIFKV 593
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH 1386
+R +V +L+ ++ SI ++L + +F ++FA++G+QLF G++
Sbjct: 594 TKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQF------------- 640
Query: 1387 EIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPI 1446
N+ P NFD A + +FQ+ T + W ++M D I S Q
Sbjct: 641 ------------NFDEGTPPTNFDTFPAAIMTVFQILTGEDWNEVMYDGIKS-----QGG 683
Query: 1447 RETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAM 1506
+ + +Y LN+F+ + +DN ++ E +QK
Sbjct: 684 VQGGMVFSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAANQKLALQKA 743
Query: 1507 KKMGSKKPLKA 1517
K++ PL A
Sbjct: 744 KEVAEVSPLSA 754
Score = 93.9 bits (223), Expect = 4e-17
Identities = 71/271 (26%), Positives = 133/271 (49%), Gaps = 21/271 (7%)
Query: 1524 RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSEC 1583
R + + +V + F ++ + LN L + + HY Q E S L Y IF+ +F SE
Sbjct: 475 RMRFYIRRMVKTQAFYWTVLSLVALNTLCVAIVHYNQPEWLSDFLYYAEFIFLGLFMSEM 534
Query: 1584 LLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVL 1642
+K++ L YF +N FD V++ SI ++ + I ++LR +R+ R+
Sbjct: 535 FIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVIWAVIKPGTSFGISVLRALRLL---RIF 591
Query: 1643 RLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNF 1702
++ K +R L+ +L S+ ++ ++ LLFL + +FA+ GM F + NF
Sbjct: 592 KVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFDEGTPPTNF 651
Query: 1703 KTFVQSMILLFQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYL 1761
TF +++ +FQ+ T W+ V+ DGI + G G I +++ L
Sbjct: 652 DTFPAAIMTVFQILTGEDWNEVMYDGI------------KSQGGVQGGMVFSIYFIVLTL 699
Query: 1762 VISFLIVINMYIAVILENYSQA---TEDVQE 1789
++ + +N+++A+ ++N + A T+D QE
Sbjct: 700 FGNYTL-LNVFLAIAVDNLANAQELTKDEQE 729
Score = 92.3 bits (219), Expect = 1e-16
Identities = 80/293 (27%), Positives = 141/293 (48%), Gaps = 35/293 (11%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPH--RPILQDILYYMDRIFTVIFFIEMLIK 1270
K+ E FE ++ I+ + + LALE HLP + + + L + F IF E IK
Sbjct: 93 KITEWPPFEYMILATIIANCIVLALEQ-HLPDDDKTPMSERLDDTEPYFIGIFCFEAGIK 151
Query: 1271 WLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
+ALGF Y N W +DF++V+ ++ V G +T+R +R LRPL+
Sbjct: 152 IIALGFAFHKGSYLRNGWNVMDFVVVLTGILATV------GTEFDLRTLRAVRVLRPLKL 205
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYF-KCVDMNHTTLS 1385
+S + ++VV+ ++++A+ + + L+ LIFAI+G++ + GK+ C + +
Sbjct: 206 VSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCFEEGTDDIQ 265
Query: 1386 HEI-IP---DKNACTLENYT-----WE---NSPMNFDHVGKAYLCLFQVATFKGWIQIMN 1433
E P ++ A T N T WE N FD++ A L +FQ T +GW ++
Sbjct: 266 GESPAPCGTEEPARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLY 325
Query: 1434 DAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
++ D+ N + +LY LNL +GV+ F +++++
Sbjct: 326 NSNDA---------SGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERER 369
Score = 68.9 bits (161), Expect = 1e-09
Identities = 52/159 (32%), Positives = 80/159 (50%), Gaps = 17/159 (10%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSET---FSAVLDYLNMIFIVIFSSECLLKIFAL--RY 1592
F+ +I+ I N + + L+ + + S LD FI IF E +KI AL +
Sbjct: 100 FEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAF 159
Query: 1593 H---YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
H Y WN+ DFVVV+ IL+ V ++ LR +R +V R L+LV G
Sbjct: 160 HKGSYLRNGWNVMDFVVVLTGILATVGTEFD---------LRTLRAVRVLRPLKLVSGIP 210
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
++ +L ++ ++ L I LLLF + IFAI G+ F+M
Sbjct: 211 SLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYM 249
Score = 67.3 bits (157), Expect = 4e-09
Identities = 40/102 (39%), Positives = 64/102 (62%), Gaps = 9/102 (8%)
Query: 827 LKSGNYLRVFKLAKSWPTL-NLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY 885
L++ LR+FK+ K W +L NL++S++ +M ++ +L F+L + I +FA++GMQLFG +
Sbjct: 582 LRALRLLRIFKVTKYWASLRNLVVSLLN-SMKSIISLLFLLFLFIVVFALLGMQLFGGQF 640
Query: 886 VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWD 926
F +G P NF F + M VF++L GE W E M+D
Sbjct: 641 -----NFDEG-TPPTNFDTFPAAIMTVFQILTGEDWNEVMYD 676
Score = 64.5 bits (150), Expect = 3e-08
Identities = 43/156 (27%), Positives = 78/156 (50%), Gaps = 16/156 (10%)
Query: 138 LVHPLFSLFIITTILVNCILMIMP---TTPTVEST----EVIFTGIYTFESAVKVMARGF 190
+V P F I+ I +N I+++M + E+ ++FT +++ E +KVMA G
Sbjct: 1563 VVSPPFEYTIMAMIALNTIVLMMKFYGASVAYENALRVFNIVFTSLFSLECVLKVMAFGI 1622
Query: 191 ILQPFTYLRDAWNWLDFVVIA-----LAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGL 245
+ Y RDAWN DFV + + G + NL+ LR FR R +K + +
Sbjct: 1623 L----NYFRDAWNIFDFVTVLGSITDILVTEFGNNFINLSFLRLFRAARLIKLLRQGYTI 1678
Query: 246 KTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+ ++ ++S K L V +L ++A++G+Q++
Sbjct: 1679 RILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF 1714
Score = 52.4 bits (120), Expect = 1e-04
Identities = 30/100 (30%), Positives = 51/100 (51%), Gaps = 5/100 (5%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
R+ KL + T+ +L+ ++ AL + ++ ++ FI+A++GMQ+FG +D D
Sbjct: 1667 RLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIGIDVEDEDS 1726
Query: 894 DGD----LPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
D D NF F + M++FR GE W M C+
Sbjct: 1727 DEDEFQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCL 1766
Score = 47.6 bits (108), Expect = 0.003
Identities = 34/121 (28%), Positives = 60/121 (49%), Gaps = 12/121 (9%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIA-------LAYVTMGIDLG 222
E IF G++ E +K+ G +P Y ++N D VI A + G G
Sbjct: 523 EFIFLGLFMSEMFIKMYGLG--TRP--YFHSSFNCFDCGVIIGSIFEVIWAVIKPGTSFG 578
Query: 223 NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYM 282
++ LR R+LR K L+ +V +++ S+K++ ++ L + VFAL+G+Q++
Sbjct: 579 -ISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFG 637
Query: 283 G 283
G
Sbjct: 638 G 638
>UniRef50_A4RYT5 Cluster: VIC family transporter: calcium ion channel;
n=3; cellular organisms|Rep: VIC family transporter:
calcium ion channel - Ostreococcus lucimarinus CCE9901
Length = 1701
Score = 315 bits (773), Expect = 9e-84
Identities = 204/649 (31%), Positives = 327/649 (50%), Gaps = 58/649 (8%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+R F + ++ F+ ++ +I+ SS+ + E P ++ +D FT F +E
Sbjct: 897 VRKACFAIADDRRFDWFILMLIIASSITMCWETPENMDNPNFEERAEILDYCFTSAFVVE 956
Query: 1267 MLIKWLALGF-----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRAL 1321
+L+KW+ALG Y N W LD IV L+ L + ++ + +RTLR L
Sbjct: 957 LLMKWIALGMFNADKYSYLKNPWNVLDGTIVFFGLLGM--GLGSSADLKWVRALRTLRVL 1014
Query: 1322 RPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD--- 1378
RPLR + R+QG++VV+NAL+ ++PS+ VLLV LI W+IFAI G+ LF GK+ C D
Sbjct: 1015 RPLRLLGRVQGLKVVINALIASLPSLVYVLLVSLIVWIIFAIAGMSLFMGKFKSCSDPTI 1074
Query: 1379 ----------MNHTTL-SHEIIPD---------KNACTLENYT--------WENSPMNFD 1410
N T++ + ++I ++ACT +YT WE++ NFD
Sbjct: 1075 LTKSACVDSWSNGTSVRTWDVITSSCNDYTKTTESACT-GSYTSAVYVTRDWESADSNFD 1133
Query: 1411 HVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLN 1470
+A L LF+ + +GW M +A D+ P+R+ Y N
Sbjct: 1134 SFPRAMLTLFETTSGEGWTVTMFNAADAVGTDVAPVRDRTPVATWYFLIFIVLSNFFLFN 1193
Query: 1471 LFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRP---RWRPQA 1527
+ IG++IDNF K M+E Q ++ + RP +WR A
Sbjct: 1194 MCIGIVIDNF--LKISTTSLTRTIMSESQARWVAQQRNRNFTARQSFFRRPPHQKWR--A 1249
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKI 1587
+F+++ D +FD IM+ I +N + + + S + LD LN IF F+ E ++KI
Sbjct: 1250 KLFQLINDTRFDASIMVIIFINTVVLMTETDHDSSSKKFALDVLNYIFTAAFAVEAMMKI 1309
Query: 1588 FALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVK 1646
AL YF WN+FDF++V+ SIL +L S T R ++ RV R+VK
Sbjct: 1310 GALYPRRYFSSGWNVFDFIIVVTSILGAILQ--------SGTGSSAFRALRICRVFRMVK 1361
Query: 1647 GAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFV 1706
K + TL L M++PAL NI LLL L+ FI+AI G F + L+ NFKTF
Sbjct: 1362 KWKSLNTLFQTLVMTIPALGNISLLLALLFFIYAILGTQVFGRLAYGEALNRHANFKTFG 1421
Query: 1707 QSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFL 1766
S+ L +M T GW +++ +N++ CD + + G C + Y +S++ S
Sbjct: 1422 NSLSTLLRMLTGEGWQEIMNDCMNKKNCDASFD--CAIGTCCGTAVAPVYFVSFVAFSSF 1479
Query: 1767 IVINMYIAVILENYSQATEDVQ-EGLTDDDYDMYYEIWQRFDPDGSQYI 1814
I++N+ IAV+L+NYS + ++ + E +T +D + +W++FDPD + ++
Sbjct: 1480 IILNLLIAVVLDNYSMSRKEAENENVTPEDVKAFRRVWKKFDPDLTGFV 1528
Score = 138 bits (335), Expect = 1e-30
Identities = 81/262 (30%), Positives = 146/262 (55%), Gaps = 23/262 (8%)
Query: 167 ESTEVIFTGIYTFESAVKVMARGFILQPFT-----YLRDAWNWLDFVVIALAYVTM-GID 220
E +E+ FT ++T E+ +K++A G + + T YLRD+WN +DF ++ ++ V + D
Sbjct: 199 ERSELTFTILFTLEALLKMIAFGVVGKLNTKNSGAYLRDSWNVMDFGIVIVSVVALLPGD 258
Query: 221 LG-NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQ 279
+G N++ LRT R+LR L+T+++ P L+ ++ +++S+ L +VI+ + +F ++G+Q
Sbjct: 259 MGSNVSTLRTVRILRPLRTISMFPSLRLLIETMLKSLPLLANVIVFFLLFFCIFGIIGVQ 318
Query: 280 IYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETN--WYGEGGDYPLCGNSS-GAGQC 336
+ G + +C V P + T + + R + + + + CG ++ A QC
Sbjct: 319 FFAGKMRTRCFDVLPPSVPCESYTAQEYVRCIKRASGDAVLLKKNEDQACGTTAQAAWQC 378
Query: 337 EPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENL-----------YQLFFV 385
G CL NPNYGY SFD+ W++L F+ +T +YW + ++F+
Sbjct: 379 PSGQECLD--HENPNYGYASFDSVWWSWLVIFQTITLEYWSPVMLDLIDSVSPAVVMWFL 436
Query: 386 VIIFLGSFYLVNLILAIVAMSY 407
+IF GSF ++NL LAI+ M Y
Sbjct: 437 PVIFFGSFVILNLALAIITMVY 458
Score = 91.1 bits (216), Expect = 3e-16
Identities = 70/228 (30%), Positives = 107/228 (46%), Gaps = 10/228 (4%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
K ++ +F + ILL++L LA+E + + + L + FT IF E+LIK +
Sbjct: 532 KFVDGDFFFMVINFSILLNTLVLAMEYDGMSNS--YSEALENANLAFTAIFMFELLIKVV 589
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG 1332
ALG +Y + WLD IV+VS I L G G F +R LR R L+ M Q
Sbjct: 590 ALGIPEYVRDRMNWLDAGIVLVSCIEL--GLNGGEGKSKFTVLRALRVFRILKLMRTWQS 647
Query: 1333 MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD----MNHTTLSHEI 1388
++ + + + + + + L + +F LIFA++G+QLF G Y K +D N T ++ I
Sbjct: 648 LQSTLKTIWKTLVDLSSFLAILCLFVLIFALVGMQLFGGNYCK-IDPKPRSNFDTFNNAI 706
Query: 1389 IPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAI 1436
I T E++ F K L F V G I+N I
Sbjct: 707 ITVVQVITHEDWPLVMYDTMFT-TAKVALLYFVVVLILGDFIILNSLI 753
Score = 85.4 bits (202), Expect = 1e-14
Identities = 54/184 (29%), Positives = 96/184 (52%), Gaps = 14/184 (7%)
Query: 114 RFSATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTV------E 167
+F ++ + P +P+R+ I F FI+ I+ + I M T + E
Sbjct: 881 KFEQSSFFGLFKPSHPVRKACFAIADDRRFDWFILMLIIASSITMCWETPENMDNPNFEE 940
Query: 168 STEVI---FTGIYTFESAVKVMARG-FILQPFTYLRDAWNWLDFVVIALAYVTMGI---- 219
E++ FT + E +K +A G F ++YL++ WN LD ++ + MG+
Sbjct: 941 RAEILDYCFTSAFVVELLMKWIALGMFNADKYSYLKNPWNVLDGTIVFFGLLGMGLGSSA 1000
Query: 220 DLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQ 279
DL + ALRT RVLR L+ + V GLK ++ A+I S+ +L V+++++ +FA+ G+
Sbjct: 1001 DLKWVRALRTLRVLRPLRLLGRVQGLKVVINALIASLPSLVYVLLVSLIVWIIFAIAGMS 1060
Query: 280 IYMG 283
++MG
Sbjct: 1061 LFMG 1064
Score = 83.4 bits (197), Expect = 6e-14
Identities = 59/192 (30%), Positives = 100/192 (52%), Gaps = 23/192 (11%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVH---------LPHRPILQDILYYMDR 1257
+R +L+E F+ V+ +I +++ L L + R D +
Sbjct: 144 IRKFCIQLVERHEFDWIVLLIIAANTILLCLSEPERLEGRGCGQFATRGARNDAAERSEL 203
Query: 1258 IFTVIFFIEMLIKWLALGFQ---------KYFTNAWCWLDFIIVMVSLINFVAALCGAGG 1308
FT++F +E L+K +A G Y ++W +DF IV+VS+ VA L G G
Sbjct: 204 TFTILFTLEALLKMIAFGVVGKLNTKNSGAYLRDSWNVMDFGIVIVSV---VALLPGDMG 260
Query: 1309 IQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQL 1368
T+RT+R LRPLR +S +R+++ +++++P + NV++ L+F+ IF I+GVQ
Sbjct: 261 SNV-STLRTVRILRPLRTISMFPSLRLLIETMLKSLPLLANVIVFFLLFFCIFGIIGVQF 319
Query: 1369 FAGKY-FKCVDM 1379
FAGK +C D+
Sbjct: 320 FAGKMRTRCFDV 331
Score = 83.4 bits (197), Expect = 6e-14
Identities = 64/219 (29%), Positives = 103/219 (47%), Gaps = 17/219 (7%)
Query: 1482 EQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKK----PLKAIPRPRWRPQAIVFEIVTDKK 1537
E+ S+ M + QKK A+ K+ K + +P + F I D++
Sbjct: 850 EESSAETTSVIMSPKDMQKKQPGALSKVPLTKFEQSSFFGLFKPSHPVRKACFAIADDRR 909
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSET--FSAVLDYLNMIFIVIFSSECLLKIFAL----- 1590
FD I++ I + +TM + + + F + L+ F F E L+K AL
Sbjct: 910 FDWFILMLIIASSITMCWETPENMDNPNFEERAEILDYCFTSAFVVELLMKWIALGMFNA 969
Query: 1591 -RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
+Y Y PWN+ D +V F +L + L + +V R +R +V R LRL+ +
Sbjct: 970 DKYSYLKNPWNVLDGTIVFFGLLGMGLGSSADLKWV-----RALRTLRVLRPLRLLGRVQ 1024
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
G++ ++ AL SLP+L + L+ +V IFAI GMS FM
Sbjct: 1025 GLKVVINALIASLPSLVYVLLVSLIVWIIFAIAGMSLFM 1063
Score = 78.2 bits (184), Expect = 2e-12
Identities = 67/257 (26%), Positives = 120/257 (46%), Gaps = 23/257 (8%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFV- 1596
F M+I I LN L + +++ S ++S L+ N+ F IF E L+K+ AL +V
Sbjct: 539 FFMVINFSILLNTLVLAMEYDGMSNSYSEALENANLAFTAIFMFELLIKVVALGIPEYVR 598
Query: 1597 EPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLF 1656
+ N D +V+ S + L L+ K + V+R +V R+L+L++ + +++ L
Sbjct: 599 DRMNWLDAGIVLVSCIELGLNGGEGK-----SKFTVLRALRVFRILKLMRTWQSLQSTLK 653
Query: 1657 ALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMS 1716
+ +L L + +L L + IFA+ GM F K NF TF ++I + Q+
Sbjct: 654 TIWKTLVDLSSFLAILCLFVLIFALVGMQLFGGNYCKIDPKPRSNFDTFNNAIITVVQVI 713
Query: 1717 TSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVI 1776
T W V+ + +A + + Y + L++ I++N IA++
Sbjct: 714 THEDWPLVMYDTM-----------------FTTAKVALLYFVVVLILGDFIILNSLIAIL 756
Query: 1777 LENYSQATEDVQEGLTD 1793
L N+ E +QE L +
Sbjct: 757 LSNFDNRKEVLQEQLQE 773
Score = 68.9 bits (161), Expect = 1e-09
Identities = 43/126 (34%), Positives = 69/126 (54%), Gaps = 12/126 (9%)
Query: 805 IVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTF 864
IVV ++ A+ +AL+ RVF++ K W +LN L + T+ ALGN++
Sbjct: 1329 IVVTSILGAILQSGTGSSAFRALR---ICRVFRMVKKWKSLNTLFQTLVMTIPALGNISL 1385
Query: 865 VLCIIIFIFAVMGMQLFGK-NYVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIE 922
+L ++ FI+A++G Q+FG+ Y + ++R NF F +S + R+L GE W E
Sbjct: 1386 LLALLFFIYAILGTQVFGRLAYGEALNRHA-------NFKTFGNSLSTLLRMLTGEGWQE 1438
Query: 923 SMWDCM 928
M DCM
Sbjct: 1439 IMNDCM 1444
Score = 63.3 bits (147), Expect = 6e-08
Identities = 41/152 (26%), Positives = 80/152 (52%), Gaps = 15/152 (9%)
Query: 143 FSLFIITTILVNCILMIMPT-------TPTVESTEVIFTGIYTFESAVKVMARGFILQPF 195
F + I +IL+N +++ M + +E+ + FT I+ FE +KV+A G P
Sbjct: 539 FFMVINFSILLNTLVLAMEYDGMSNSYSEALENANLAFTAIFMFELLIKVVALGI---P- 594
Query: 196 TYLRDAWNWLDFVVIALAYVTMGIDLGN----LAALRTFRVLRALKTVAIVPGLKTIVGA 251
Y+RD NWLD ++ ++ + +G++ G LR RV R LK + L++ +
Sbjct: 595 EYVRDRMNWLDAGIVLVSCIELGLNGGEGKSKFTVLRALRVFRILKLMRTWQSLQSTLKT 654
Query: 252 VIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
+ +++ +L + + + +FAL+G+Q++ G
Sbjct: 655 IWKTLVDLSSFLAILCLFVLIFALVGMQLFGG 686
Score = 62.9 bits (146), Expect = 9e-08
Identities = 35/120 (29%), Positives = 64/120 (53%), Gaps = 7/120 (5%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L++ R+ KL ++W +L + + +T+ L + +LC+ + IFA++GMQLFG NY
Sbjct: 630 LRALRVFRILKLMRTWQSLQSTLKTIWKTLVDLSSFLAILCLFVLIFALVGMQLFGGNYC 689
Query: 887 DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSCIPFFLATVVI 945
+D PR NF F ++ + V +V+ E W M+D M + +F+ +++
Sbjct: 690 K-ID-----PKPRSNFDTFNNAIITVVQVITHEDWPLVMYDTMFTTAKVALLYFVVVLIL 743
Score = 56.8 bits (131), Expect = 6e-06
Identities = 44/217 (20%), Positives = 90/217 (41%), Gaps = 15/217 (6%)
Query: 115 FSATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEV--- 171
F+A + + P R ++ F I+ I +N ++++ T S +
Sbjct: 1232 FTARQSFFRRPPHQKWRAKLFQLINDTRFDASIMVIIFINTVVLMTETDHDSSSKKFALD 1291
Query: 172 IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLG-NLAALRTF 230
+ I+T AV+ M + L P Y WN DF+++ + + + G +A R
Sbjct: 1292 VLNYIFTAAFAVEAMMKIGALYPRRYFSSGWNVFDFIIVVTSILGAILQSGTGSSAFRAL 1351
Query: 231 RVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCV 290
R+ R + V L T+ ++ ++ L ++ +L ++A++G Q++ + + +
Sbjct: 1352 RICRVFRMVKKWKSLNTLFQTLVMTIPALGNISLLLALLFFIYAILGTQVFGRLAYGEAL 1411
Query: 291 KVFPEDGSWGN--------LTDENWERF---CQNETN 316
++GN LT E W+ C N+ N
Sbjct: 1412 NRHANFKTFGNSLSTLLRMLTGEGWQEIMNDCMNKKN 1448
Score = 56.4 bits (130), Expect = 7e-06
Identities = 49/178 (27%), Positives = 81/178 (45%), Gaps = 28/178 (15%)
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSE--------TFSAVLDYLN---MIFIVIF 1579
++V +FD I++L I N + + L ++ E T A D + F ++F
Sbjct: 150 QLVERHEFDWIVLLIIAANTILLCLSEPERLEGRGCGQFATRGARNDAAERSELTFTILF 209
Query: 1580 SSECLLKIFALRY----------HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTL 1629
+ E LLK+ A Y + WN+ DF +V+ S+++L+ D+ +
Sbjct: 210 TLEALLKMIAFGVVGKLNTKNSGAYLRDSWNVMDFGIVIVSVVALLPGDMGSNV----ST 265
Query: 1630 LRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
LR VR+ R LR + +R L+ + SLP L N+ + L IF I G+ FF
Sbjct: 266 LRTVRIL---RPLRTISMFPSLRLLIETMLKSLPLLANVIVFFLLFFCIFGIIGVQFF 320
>UniRef50_P91744 Cluster: Voltage-dependent calcium channel; n=1;
Loligo bleekeri|Rep: Voltage-dependent calcium channel -
Loligo bleekeri (Bleeker's squid)
Length = 2196
Score = 315 bits (773), Expect = 9e-84
Identities = 186/676 (27%), Positives = 354/676 (52%), Gaps = 29/676 (4%)
Query: 1219 YFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGF-- 1276
YF+ ++ +I SS+ALA ED + + IL Y D +FT +F IEML+K + LG
Sbjct: 896 YFDLFIMIVICASSIALAAEDP-VNDESVNNQILNYFDYVFTGVFTIEMLLKIVDLGIIL 954
Query: 1277 --QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMR 1334
Y +AW LD +V+ +L+ F G + K++R LR LRPL+ ++R+ ++
Sbjct: 955 HPGSYCRDAWNILDATVVICALVAFAFGDAAGGNLNTIKSLRVLRVLRPLKTINRIPKLK 1014
Query: 1335 VVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH------EI 1388
V + +V ++ ++ N+L+V L+F IFA++ VQLF GK+F C DM+ + +
Sbjct: 1015 AVFDCVVNSLKNVSNILIVYLLFQFIFAVIAVQLFKGKFFYCTDMSKSNREECQGQYFDY 1074
Query: 1389 IPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRE 1448
+ + ++N W ++D+V A L LF V T +GW ++ +++DS P
Sbjct: 1075 EDESDKPRVKNREWLRQDFHYDNVMFAMLTLFTVTTGEGWPMVLKNSMDSTSDDMGPKPG 1134
Query: 1449 TNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKK 1508
+ M +Y +N+F+ +II F EQ + ++ + ++QK+
Sbjct: 1135 YRMEMAIYYVVFFIVFPFFFVNIFVALIIITFQEQGENE--LVDQDLDKNQKQCIEF--S 1190
Query: 1509 MGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVL 1568
+ +K + +P+ + + ++++V KF+ ++M+ I LN L + + +Y + +L
Sbjct: 1191 IEAKPSCRYVPKNKNSIKYKIWQVVVSPKFECVVMVLIALNTLVLMMKYYGSPTEYKLLL 1250
Query: 1569 DYLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSP 1627
LN+ F V+F+ EC+LK+ +YF + WN+FDF++V+ SI+ +V ++++ S
Sbjct: 1251 QNLNLAFSVLFTIECILKLMGFGIGNYFRDRWNMFDFIIVIGSIIDVVTTNVLPS--ASS 1308
Query: 1628 TLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
R+ + R+++L++ IR LL+ S AL +CLL+ ++ FI+AI GM F
Sbjct: 1309 FRTGSFRLFRAARLVKLLRQGYTIRLLLWTFLQSFKALPYVCLLIAMLFFIYAIIGMQVF 1368
Query: 1688 MHVK--DKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPG 1745
+++ K ++ NF++F +++LLF+ +T W ++ ++ CD P+++
Sbjct: 1369 GNIRLDSKTSINRHNNFRSFFYAVLLLFRCATGESWQQIMLSCLSGRPCD-PESKM-LDN 1426
Query: 1746 NCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQR 1805
+CG I Y ++++ + +++N+++AVI++N+ T D L D Y +W
Sbjct: 1427 SCG-LDIAYIYFVTFIFLCSFLMLNLFVAVIMDNFDYLTRDTSI-LGPHHLDEYSRVWAE 1484
Query: 1806 FDPDGSQYIRYDQLSDFLDVLEPPLQIHKPNKY-----KIISMDIPICRGDMMFCVDILD 1860
+DP S + Y + + L +EPP+ + Y K+I M++P+ + L
Sbjct: 1485 YDPLASGRVHYTDMYEMLRRMEPPVGFGRNCPYRLACRKLIRMNMPLKEDGTVHFSTTLF 1544
Query: 1861 ALTKDFFARKGNPIEE 1876
AL ++ + + + EE
Sbjct: 1545 ALVRESLSIRMSSAEE 1560
Score = 152 bits (369), Expect = 8e-35
Identities = 97/314 (30%), Positives = 163/314 (51%), Gaps = 40/314 (12%)
Query: 116 SATN-ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM----------PTTP 164
S+TN +L+I N IR+ A I+ F ++ TI+ NCI++ + P
Sbjct: 39 SSTNRSLFIFSEENFIRKYAKIIIEWGPFEYMVLLTIIANCIVLALEEHLPNEDKTPLAV 98
Query: 165 TVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM--GIDLG 222
+E+TE F GI+ E+ +K++A GF L +YLR+ WN +DFVV+ ++++ +
Sbjct: 99 QLEATEFYFLGIFCVEALLKIVALGFALHKGSYLRNVWNIMDFVVVVTGFISIFPASNSF 158
Query: 223 NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYM 282
+L LR RVLR LK V+ +P L+ ++ ++I ++ L V +L +F++ +FA++GL+ Y
Sbjct: 159 DLRTLRAVRVLRPLKLVSGIPSLQVVLKSIIRAMAPLLQVCLLVLFAIVIFAIIGLEFYT 218
Query: 283 GVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVC 342
G + C + P D S N+ YG+ C N C
Sbjct: 219 GAFHKACF-IKPNDDSEDNIE--------------YGDEDTIRPCANEGSGYHCRANIAK 263
Query: 343 LQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYW-ENLYQ-----------LFFVVIIFL 390
+ PNYG TSFD G+A L+ F+ +T + W + LY ++FV +I L
Sbjct: 264 CRFNWAGPNYGITSFDNMGFAMLTVFQCVTMEGWTQVLYYTDDAVGDAYNWIYFVPLIVL 323
Query: 391 GSFYLVNLILAIVA 404
GSF+++NL+L +++
Sbjct: 324 GSFFMLNLVLGVLS 337
Score = 105 bits (253), Expect = 9e-21
Identities = 58/179 (32%), Positives = 98/179 (54%), Gaps = 14/179 (7%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVEST--------E 170
++++I P NP+RR +++ F LFI+ I + I + ES +
Sbjct: 873 SSMFIFGPTNPVRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVNDESVNNQILNYFD 932
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM------GIDLGNL 224
+FTG++T E +K++ G IL P +Y RDAWN LD V+ A V G +L +
Sbjct: 933 YVFTGVFTIEMLLKIVDLGIILHPGSYCRDAWNILDATVVICALVAFAFGDAAGGNLNTI 992
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
+LR RVLR LKT+ +P LK + V+ S+KN+ +++I+ + +FA++ +Q++ G
Sbjct: 993 KSLRVLRVLRPLKTINRIPKLKAVFDCVVNSLKNVSNILIVYLLFQFIFAVIAVQLFKG 1051
Score = 101 bits (242), Expect = 2e-19
Identities = 69/269 (25%), Positives = 136/269 (50%), Gaps = 22/269 (8%)
Query: 1533 VTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY 1592
V + F +++ + LN L + +HY Q+E + L + F+ +F SE L+K++ L
Sbjct: 478 VKTQGFYWFVIILVFLNTLCVASEHYGQAEWHTEFLYVMEFAFLALFMSEMLIKMYGLGV 537
Query: 1593 H-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGI 1651
YF +N+FD VV++ SI+ ++ S I + + LR +R+ ++ +V R +
Sbjct: 538 RLYFQSSFNIFDCVVILVSIIEVIWSAIKDGSSFGISTLRALRLLRMFKVTRY---WSSL 594
Query: 1652 RTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMIL 1711
R L+ +L S+ ++ ++ LLFL + IFA+ GM F + + +F TF +++
Sbjct: 595 RNLVVSLLSSMRSIVSLLFLLFLFILIFALLGMQLFGGMMNFEEGRPPGHFDTFPIALLT 654
Query: 1712 LFQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVIN 1770
+FQ+ T W+ V+ GI R G G + +Y + ++ ++N
Sbjct: 655 VFQILTGEDWNEVMYSGI------------RARGGIAGGGMLYCSYFIILVLFGNYTLLN 702
Query: 1771 MYIAVILENYSQ-----ATEDVQEGLTDD 1794
+++A+ ++N + A E++QEG+ +
Sbjct: 703 VFLAIAVDNLANAQELTAAEEIQEGVRQE 731
Score = 98.7 bits (235), Expect = 1e-18
Identities = 78/302 (25%), Positives = 136/302 (45%), Gaps = 32/302 (10%)
Query: 1200 FWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIF 1259
FW+ LR K ++ F VI ++ L++L +A E H + LY M+ F
Sbjct: 463 FWRAEKHLRFTIRKCVKTQGFYWFVIILVFLNTLCVASE--HYGQAEWHTEFLYVMEFAF 520
Query: 1260 TVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLR 1319
+F EMLIK LG + YF +++ D ++++VS+I + + G T+R LR
Sbjct: 521 LALFMSEMLIKMYGLGVRLYFQSSFNIFDCVVILVSIIEVIWSAIKDGSSFGISTLRALR 580
Query: 1320 ALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDM 1379
LR + +R +V +L+ ++ SI ++L + +F LIFA++G+QLF G
Sbjct: 581 LLRMFKVTRYWSSLRNLVVSLLSSMRSIVSLLFLLFLFILIFALLGMQLFGG-------- 632
Query: 1380 NHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSR 1439
+ N+ P +FD A L +FQ+ T + W ++M I +
Sbjct: 633 -----------------MMNFEEGRPPGHFDTFPIALLTVFQILTGEDWNEVMYSGIRA- 674
Query: 1440 EVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNF-NEQKKKAGGSLEMFMTED 1498
R I + Y LN+F+ + +DN N Q+ A ++ + ++
Sbjct: 675 ---RGGIAGGGMLYCSYFIILVLFGNYTLLNVFLAIAVDNLANAQELTAAEEIQEGVRQE 731
Query: 1499 QK 1500
Q+
Sbjct: 732 QE 733
Score = 94.7 bits (225), Expect = 2e-17
Identities = 82/300 (27%), Positives = 144/300 (48%), Gaps = 41/300 (13%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPH--RPILQDILYYMDRIFTVIFFIEMLIKW 1271
+IE FE V+ I+ + + LALE+ HLP+ + L L + F IF +E L+K
Sbjct: 61 IIEWGPFEYMVLLTIIANCIVLALEE-HLPNEDKTPLAVQLEATEFYFLGIFCVEALLKI 119
Query: 1272 LALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAM 1327
+ALGF Y N W +DF++V+ I+ A +T+R +R LRPL+ +
Sbjct: 120 VALGFALHKGSYLRNVWNIMDFVVVVTGFISIFPA----SNSFDLRTLRAVRVLRPLKLV 175
Query: 1328 SRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHE 1387
S + ++VV+ ++++A+ + V L+ L +IFAI+G++ + G + K + S +
Sbjct: 176 SGIPSLQVVLKSIIRAMAPLLQVCLLVLFAIVIFAIIGLEFYTGAFHKACFIKPNDDSED 235
Query: 1388 IIP--DKNA---CTLE-------------NYTWEN---SPMNFDHVGKAYLCLFQVATFK 1426
I D++ C E + W +FD++G A L +FQ T +
Sbjct: 236 NIEYGDEDTIRPCANEGSGYHCRANIAKCRFNWAGPNYGITSFDNMGFAMLTVFQCVTME 295
Query: 1427 GWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
GW Q++ D+ VG + Y ++Y LNL +GV+ F +++++
Sbjct: 296 GWTQVLYYTDDA--VG-------DAYNWIYFVPLIVLGSFFMLNLVLGVLSGEFAKERER 346
Score = 70.9 bits (166), Expect = 3e-10
Identities = 46/158 (29%), Positives = 80/158 (50%), Gaps = 15/158 (9%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSET---FSAVLDYLNMIFIVIFSSECLLKIFALRY-- 1592
F+ +++L I N + + L+ + +E + L+ F+ IF E LLKI AL +
Sbjct: 67 FEYMVLLTIIANCIVLALEEHLPNEDKTPLAVQLEATEFYFLGIFCVEALLKIVALGFAL 126
Query: 1593 ---HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
Y WN+ DFVVV+ +S+ + + LR +R +V R L+LV G
Sbjct: 127 HKGSYLRNVWNIMDFVVVVTGFISIFPAS-------NSFDLRTLRAVRVLRPLKLVSGIP 179
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
++ +L ++ ++ L +CLL+ + IFAI G+ F+
Sbjct: 180 SLQVVLKSIIRAMAPLLQVCLLVLFAIVIFAIIGLEFY 217
Score = 58.4 bits (135), Expect = 2e-06
Identities = 36/101 (35%), Positives = 64/101 (63%), Gaps = 9/101 (8%)
Query: 827 LKSGNYLRVFKLAKSWPTL-NLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY 885
L++ LR+FK+ + W +L NL++S++ +M ++ +L F+L + I IFA++GMQLFG
Sbjct: 576 LRALRLLRMFKVTRYWSSLRNLVVSLLS-SMRSIVSLLFLLFLFILIFALLGMQLFG-GM 633
Query: 886 VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMW 925
+++ + P G +F F + + VF++L GE W E M+
Sbjct: 634 MNFEEGRPPG-----HFDTFPIALLTVFQILTGEDWNEVMY 669
Score = 55.2 bits (127), Expect = 2e-05
Identities = 41/169 (24%), Positives = 87/169 (51%), Gaps = 20/169 (11%)
Query: 128 NPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT--TPT-----VESTEVIFTGIYTFE 180
N I+ ++V P F ++ I +N ++++M +PT +++ + F+ ++T E
Sbjct: 1205 NSIKYKIWQVVVSPKFECVVMVLIALNTLVLMMKYYGSPTEYKLLLQNLNLAFSVLFTIE 1264
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVI---ALAYVTMGIDLGNLAALRT--FRVLRA 235
+K+M G Y RD WN DF+++ + VT + L + ++ RT FR+ RA
Sbjct: 1265 CILKLMGFGI----GNYFRDRWNMFDFIIVIGSIIDVVTTNV-LPSASSFRTGSFRLFRA 1319
Query: 236 LKTVAIVP---GLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+ V ++ ++ ++ ++S K L V +L ++A++G+Q++
Sbjct: 1320 ARLVKLLRQGYTIRLLLWTFLQSFKALPYVCLLIAMLFFIYAIIGMQVF 1368
Score = 47.6 bits (108), Expect = 0.003
Identities = 30/123 (24%), Positives = 63/123 (51%), Gaps = 12/123 (9%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM-------GIDLG 222
E F ++ E +K+ G L Y + ++N D VVI ++ + + G G
Sbjct: 517 EFAFLALFMSEMLIKMYGLGVRL----YFQSSFNIFDCVVILVSIIEVIWSAIKDGSSFG 572
Query: 223 NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYM 282
++ LR R+LR K L+ +V +++ S++++ ++ L + +FAL+G+Q++
Sbjct: 573 -ISTLRALRLLRMFKVTRYWSSLRNLVVSLLSSMRSIVSLLFLLFLFILIFALLGMQLFG 631
Query: 283 GVL 285
G++
Sbjct: 632 GMM 634
Score = 47.2 bits (107), Expect = 0.005
Identities = 27/96 (28%), Positives = 51/96 (53%), Gaps = 5/96 (5%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
R+ KL + T+ LL+ ++ AL + ++ ++ FI+A++GMQ+FG +D
Sbjct: 1321 RLVKLLRQGYTIRLLLWTFLQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIRLDSKTSIN 1380
Query: 894 DGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
+ NF F ++ +++FR GE W + M C+
Sbjct: 1381 RHN----NFRSFFYAVLLLFRCATGESWQQIMLSCL 1412
>UniRef50_O95180 Cluster: Voltage-dependent T-type calcium channel
subunit alpha-1H; n=33; Amniota|Rep: Voltage-dependent
T-type calcium channel subunit alpha-1H - Homo sapiens
(Human)
Length = 2353
Score = 315 bits (773), Expect = 9e-84
Identities = 183/633 (28%), Positives = 336/633 (53%), Gaps = 40/633 (6%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEM 1267
R+ K+I + F+ V+ I L+ + +ALE + + L + IFT IF EM
Sbjct: 1284 RVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDPGSTERVFLSVSNYIFTAIFVAEM 1343
Query: 1268 LIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQ---AFKTMRTLRA 1320
++K +ALG Y ++W LD ++V+VSL++ V A+ AGG + + +R LR
Sbjct: 1344 MVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIVVAMASAGGAKILGVLRVLRLLRT 1403
Query: 1321 LRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMN 1380
LRPLR +SR G+++VV L+ ++ I N++L+C F++IF I+GVQLF GK++ C +
Sbjct: 1404 LRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGPD 1463
Query: 1381 HTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSRE 1440
+S K C +Y W NFD++G+A + LF +++ GW+ IM D +D+
Sbjct: 1464 TRNIS-----TKAQCRAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVG 1518
Query: 1441 VGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQK 1500
V +QP++ N +M LY LN+F+GV+++NF+ K + E ++K
Sbjct: 1519 VDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFH--KCRQHQEAEEARRREEK 1576
Query: 1501 KYYNAMKKMGSKKPL-KAIPRPRWR----PQAIVFEIVTDKKFDMIIMLFIGLNMLTMTL 1555
+ ++ S P +A RP + + + + T D+ I I +N++TM++
Sbjct: 1577 RLRRLERRRRSTFPSPEAQRRPYYADYSPTRRSIHSLCTSHYLDLFITFIICVNVITMSM 1636
Query: 1556 DHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSL 1614
+HY Q ++ L Y N +F ++F E LK+ A + +F + WN D +V+ S++ +
Sbjct: 1637 EHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSLMGI 1696
Query: 1615 VLSDI--IEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLL 1672
L +I ++PT++R++RV ++ RVL+L+K A G+R LL + +LP + N+ LL
Sbjct: 1697 TLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLF 1756
Query: 1673 FLVMFIFAIFGMSFFMHVKDK-----GGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDG 1727
L+ FI+A G+ F ++ GL F F + + LF++ST W+G++
Sbjct: 1757 MLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLTLFRVSTGDNWNGIMKD 1816
Query: 1728 IINEEECDLPDNERGSPGNCGS--ATIGITYLLSYLVISFLIVINMYIAVILENYSQATE 1785
+ EC D +C S + Y +++++++ +++N+ +AV++++ ++ +
Sbjct: 1817 TL--RECSREDK------HCLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLMKHLEESNK 1868
Query: 1786 DVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQ 1818
+ +E D + D E+ P ++ + D+
Sbjct: 1869 EARE---DAELDAEIELEMAQGPGSARRVDADR 1898
Score = 95.5 bits (227), Expect = 1e-17
Identities = 73/270 (27%), Positives = 132/270 (48%), Gaps = 32/270 (11%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR 1591
IV K F IM+ I +N L+M +++++Q E + L+ N++F +F+ E LLK+ A
Sbjct: 789 IVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEMLLKLLACG 848
Query: 1592 -YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
Y P+N+FD ++V+ S+ +V + L V+R ++ RVL+LV+
Sbjct: 849 PLGYIRNPYNIFDGIIVVISVWEIVGQ--------ADGGLSVLRTFRLLRVLKLVRFLPA 900
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF---MHVKDKGG--LDDVYNFKTF 1705
+R L L ++ + C LL L +FIF+I GM F +K G + D NF +
Sbjct: 901 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL 960
Query: 1706 VQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISF 1765
+ +++ +FQ+ T W+ VL G +++ Y ++ +
Sbjct: 961 LWAIVTVFQILTQEDWNVVLYN-----------------GMASTSSWAALYFVALMTFGN 1003
Query: 1766 LIVINMYIAVILENYSQATEDVQEGLTDDD 1795
++ N+ +A+++E + QA D TD+D
Sbjct: 1004 YVLFNLLVAILVEGF-QAEGDANRSDTDED 1032
Score = 95.1 bits (226), Expect = 2e-17
Identities = 61/166 (36%), Positives = 95/166 (57%), Gaps = 13/166 (7%)
Query: 1213 KLIENTYFETAVITMILLSSLALAL----EDVHLPHRPILQDILYYMDRIFTVIFFIEML 1268
+L+ N +FE + +I+L+ + L + EDV +IL D F +EM+
Sbjct: 95 RLVCNPWFEHVSMLVIMLNCVTLGMFRPCEDVECGSERC--NILEAFDAFIFAFFAVEMV 152
Query: 1269 IKWLALGF--QK-YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLR 1325
IK +ALG QK Y + W LDF IV+ ++ + +L G + +RT+R LRPLR
Sbjct: 153 IKMVALGLFGQKCYLGDTWNRLDFFIVVAGMMEY--SLDGHN--VSLSAIRTVRVLRPLR 208
Query: 1326 AMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
A++R+ MR++V L+ +P + NVLL+C + IF I+GVQL+AG
Sbjct: 209 AINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 254
Score = 87.4 bits (207), Expect = 3e-15
Identities = 72/287 (25%), Positives = 132/287 (45%), Gaps = 39/287 (13%)
Query: 1199 PFWQG--WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMD 1256
P W G W T K +++++ YF ++ IL+++L++ +E P L + L +
Sbjct: 772 PGWMGRLWVTFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEE--LTNALEISN 829
Query: 1257 RIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMR 1316
+FT +F +EML+K LA G Y N + D IIV++S+ V GG+ +T R
Sbjct: 830 IVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQ--ADGGLSVLRTFR 887
Query: 1317 TLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKC 1376
LR L+ +R + ++ VV LV+ + ++ + ++F IF+I+G+ LF K+
Sbjct: 888 LLRVLKLVRFLPALRRQLVV---LVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLK 944
Query: 1377 VDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAI 1436
D T +PD+ NFD + A + +FQ+ T + W ++ + +
Sbjct: 945 TDTGDT------VPDRK--------------NFDSLLWAIVTVFQILTQEDWNVVLYNGM 984
Query: 1437 DSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQ 1483
S T+ + LY NL + ++++ F +
Sbjct: 985 AS----------TSSWAALYFVALMTFGNYVLFNLLVAILVEGFQAE 1021
Score = 84.2 bits (199), Expect = 3e-14
Identities = 51/183 (27%), Positives = 95/183 (51%), Gaps = 20/183 (10%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVE--STE------- 170
AL++ P N R ++ H +F ++ I +NC+ + + P ++ STE
Sbjct: 1273 ALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALER-PDIDPGSTERVFLSVS 1331
Query: 171 -VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID--------- 220
IFT I+ E VKV+A G + YL+ +WN LD +++ ++ V + +
Sbjct: 1332 NYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIVVAMASAGGAKI 1391
Query: 221 LGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
LG L LR R LR L+ ++ PGLK +V +I S++ + +++++ +F ++G+Q+
Sbjct: 1392 LGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQL 1451
Query: 281 YMG 283
+ G
Sbjct: 1452 FKG 1454
Score = 79.0 bits (186), Expect = 1e-12
Identities = 46/172 (26%), Positives = 88/172 (51%), Gaps = 14/172 (8%)
Query: 131 RRVAIYILVHPLFSLFIITTILVNCIL--MIMPTTPT---------VESTEVIFTGIYTF 179
R + ++ +P F + I++NC+ M P +E+ + +
Sbjct: 90 RSWCLRLVCNPWFEHVSMLVIMLNCVTLGMFRPCEDVECGSERCNILEAFDAFIFAFFAV 149
Query: 180 ESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN--LAALRTFRVLRALK 237
E +K++A G Q YL D WN LDF ++ + +D N L+A+RT RVLR L+
Sbjct: 150 EMVIKMVALGLFGQK-CYLGDTWNRLDFFIVVAGMMEYSLDGHNVSLSAIRTVRVLRPLR 208
Query: 238 TVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKC 289
+ VP ++ +V +++++ L +V++L F +F ++G+Q++ G+L +C
Sbjct: 209 AINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRC 260
Score = 70.5 bits (165), Expect = 4e-10
Identities = 41/147 (27%), Positives = 82/147 (55%), Gaps = 12/147 (8%)
Query: 143 FSLFIITTILVNCILMIMP-------TTPTVESTEVIFTGIYTFESAVKVMARGFILQPF 195
FS I+ ILVN + M + T +E + ++FT ++ E +K++A G P
Sbjct: 795 FSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEMLLKLLACG----PL 850
Query: 196 TYLRDAWNWLDFVVIALA-YVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIE 254
Y+R+ +N D +++ ++ + +G G L+ LRTFR+LR LK V +P L+ + +++
Sbjct: 851 GYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLVK 910
Query: 255 SVKNLRDVIILTMFSLSVFALMGLQIY 281
++ N+ L M + +F+++G+ ++
Sbjct: 911 TMDNVATFCTLLMLFIFIFSILGMHLF 937
Score = 62.5 bits (145), Expect = 1e-07
Identities = 48/172 (27%), Positives = 82/172 (47%), Gaps = 15/172 (8%)
Query: 1524 RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTL----DHYQQSETFSAVLDYLNMIFIVIF 1579
RP++ +V + F+ + ML I LN +T+ + + + +L+ + F
Sbjct: 88 RPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMFRPCEDVECGSERCNILEAFDAFIFAFF 147
Query: 1580 SSECLLKIFALRYH----YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRV 1635
+ E ++K+ AL Y + WN DF +V+ ++ L + + VS + +R VRV
Sbjct: 148 AVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVVAGMMEYSL----DGHNVSLSAIRTVRV 203
Query: 1636 AKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
R LR + +R L+ L +LP L N+ LL F V FIF I G+ +
Sbjct: 204 L---RPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLW 252
Score = 59.3 bits (137), Expect = 1e-06
Identities = 40/173 (23%), Positives = 86/173 (49%), Gaps = 22/173 (12%)
Query: 127 FNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTE-------VIFTGIYTF 179
++P RR + LFI I VN I M M +S + +FT ++ F
Sbjct: 1603 YSPTRRSIHSLCTSHYLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVF 1662
Query: 180 ESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA-----------LR 228
E+A+K++A GF + +D WN LD ++ L+ + + ++ ++A +R
Sbjct: 1663 EAALKLVAFGF----RRFFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMR 1718
Query: 229 TFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
R+ R LK + + G++ ++ V++++ + ++ +L M ++A +G++++
Sbjct: 1719 VLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELF 1771
Score = 51.6 bits (118), Expect = 2e-04
Identities = 31/96 (32%), Positives = 50/96 (52%), Gaps = 7/96 (7%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY- 885
L++ LRV KL + P L + ++ +TM + +L + IFIF+++GM LFG +
Sbjct: 883 LRTFRLLRVLKLVRFLPALRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFS 942
Query: 886 --VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE 919
D D PD R NF + + + VF++L E
Sbjct: 943 LKTDTGDTVPD----RKNFDSLLWAIVTVFQILTQE 974
Score = 48.8 bits (111), Expect = 0.001
Identities = 26/94 (27%), Positives = 45/94 (47%), Gaps = 10/94 (10%)
Query: 1393 NACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIY 1452
N C + N +NFD++G A++ +FQV T +GW+ IM +D+ + Y
Sbjct: 345 NVCRSGDSNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAH----------SFY 394
Query: 1453 MYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
++Y +NL + VI F+E K++
Sbjct: 395 NFIYFILLIIVGSFFMINLCLVVIATQFSETKQR 428
Score = 47.6 bits (108), Expect = 0.003
Identities = 22/78 (28%), Positives = 46/78 (58%), Gaps = 12/78 (15%)
Query: 341 VCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ-----------LFFVVIIF 389
VC G NP+ G +FD G+A+++ F+++T + W ++ ++F+++I
Sbjct: 346 VCRSG-DSNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLII 404
Query: 390 LGSFYLVNLILAIVAMSY 407
+GSF+++NL L ++A +
Sbjct: 405 VGSFFMINLCLVVIATQF 422
Score = 45.6 bits (103), Expect = 0.014
Identities = 29/97 (29%), Positives = 53/97 (54%), Gaps = 4/97 (4%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
RV KL K + L+ + + + +GNL + ++ FI+A +G++LFG+ ++ + P
Sbjct: 1724 RVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGR--LECSEDNP 1781
Query: 894 DGDLPRW-NFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
L R F++F +F+ +FRV G+ W M D +
Sbjct: 1782 CEGLSRHATFSNFGMAFLTLFRVSTGDNWNGIMKDTL 1818
Score = 43.6 bits (98), Expect = 0.056
Identities = 17/38 (44%), Positives = 28/38 (73%)
Query: 796 FVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYL 833
+++LFIT I VN + M+++H+N K +D+ALK NY+
Sbjct: 1618 YLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYV 1655
Score = 42.3 bits (95), Expect = 0.13
Identities = 20/77 (25%), Positives = 43/77 (55%), Gaps = 3/77 (3%)
Query: 805 IVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTF 864
+V + +LD HN+ A+++ LR + P++ +L++++ T+ LGN+
Sbjct: 179 VVAGMMEYSLDGHNVSLS---AIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLL 235
Query: 865 VLCIIIFIFAVMGMQLF 881
+ + FIF ++G+QL+
Sbjct: 236 LCFFVFFIFGIVGVQLW 252
Score = 38.3 bits (85), Expect = 2.1
Identities = 17/54 (31%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF-GKNY 885
LR ++ P L L++ + ++ +GN+ + C IF ++G+QLF GK Y
Sbjct: 1404 LRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFY 1457
>UniRef50_Q8MQA1 Cluster: Egg laying defective protein 19, isoform b;
n=7; Bilateria|Rep: Egg laying defective protein 19,
isoform b - Caenorhabditis elegans
Length = 1877
Score = 314 bits (771), Expect = 2e-83
Identities = 204/659 (30%), Positives = 345/659 (52%), Gaps = 38/659 (5%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
++ ++YF AV+ IL+SS LA ED L IL Y D FT +F +E+ +K +
Sbjct: 794 VVNHSYFTNAVLFCILVSSAMLAAEDP-LQANSTRNMILNYFDYFFTSVFTVEITLKVIV 852
Query: 1274 LG--FQK--YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSR 1329
G F K + NA+ LD ++V VSL +FV + K +R LR LRPLRA++R
Sbjct: 853 FGLVFHKGSFCRNAFNLLDILVVAVSLTSFVLR---TDAMSVVKILRVLRVLRPLRAINR 909
Query: 1330 MQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLS---- 1385
+G++ VV ++ A+ +I N++LV + +FAI+GVQLF G +F C D++ T +
Sbjct: 910 AKGLKHVVQCVIVAVKTIGNIMLVTFMLQFMFAIIGVQLFKGTFFLCNDLSKMTEAECRG 969
Query: 1386 ---HEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVG 1442
H D + W N+ NFD+VG A + LF V+TF+GW Q++ AIDS E
Sbjct: 970 EYIHYEDGDPTKPVSKKRVWSNNDFNFDNVGDAMISLFVVSTFEGWPQLLYVAIDSNEED 1029
Query: 1443 RQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKY 1502
+ PI + + L+ +N+F+G +I F + ++ + E + ++Q+K
Sbjct: 1030 KGPIHNSRQAVALFFIAFIIVIAFFMMNIFVGFVIVTFQNEGEREYENCE--LDKNQRKC 1087
Query: 1503 YNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSE 1562
K +K + IPR R Q V+ VT + F+ +I L I +N +++ HY S
Sbjct: 1088 IEFALK--AKPHRRYIPRNRL--QYRVWWFVTSRAFEYVIFLIIVMNTVSLACKHYPSSR 1143
Query: 1563 TFSAVLDYLNMIFIVIFSSECLLKIFALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIE 1621
F LD N+IF +F+ E +LKI AL +Y + WN+FD +VV+ S + + +
Sbjct: 1144 GFEDFLDVFNLIFTGVFAFEAVLKIVALNPKNYISDRWNVFDLLVVVGSFIDITYGK-LN 1202
Query: 1622 KYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAI 1681
+ + R+ +V R+++L+ +GIRTLL+ S AL + LL+ L+ FI+A+
Sbjct: 1203 PGGTNLISINFFRLFRVMRLVKLLSRGEGIRTLLWTFMKSFQALPYVALLIVLLFFIYAV 1262
Query: 1682 FGMSFF--MHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEE--CD-- 1735
GM FF + + D + NF +F ++++LF+ +T W ++ + E+ CD
Sbjct: 1263 IGMQFFGKVALDDSTSIHRNNNFHSFPAAILVLFRSATGEAWQDIMLSCSDREDVRCDPM 1322
Query: 1736 LPDNERG--SPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTD 1793
D +G + CG+ Y +S+ ++ +VIN+++AVI++N+ T D L
Sbjct: 1323 SDDYHKGGLNESRCGN-NFAYPYFISFFMLCSFLVINLFVAVIMDNFDYLTRD-WSILGP 1380
Query: 1794 DDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHK--PNKY---KIISMDIPI 1847
+ + +W +DPD I++ + L + PPL K P++ +++SM++P+
Sbjct: 1381 HHLEEFVRLWSEYDPDAKGRIKHLDVVTLLRKISPPLGFGKLCPHRLACKRLVSMNMPL 1439
Score = 141 bits (342), Expect = 2e-31
Identities = 92/305 (30%), Positives = 159/305 (52%), Gaps = 39/305 (12%)
Query: 128 NPIRRVAIYILVHPLFSLFIITTILVNCI-LMIMPTTPT---------VESTEVIFTGIY 177
NPIR++ I I+ F I+ I NCI L I P +E+ E +F ++
Sbjct: 75 NPIRKLCISIVEWKPFEFLILFMICANCIALAIYQPYPAQDSDYKNTLLETIEYVFIVVF 134
Query: 178 TFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVT-----MGIDLGNLAALRTFRV 232
T E +K++A GF+ P YLR+AWN LDF+++ + V+ M I ++ ALR FRV
Sbjct: 135 TIECVLKIVAMGFMFHPSAYLRNAWNILDFIIVVIGLVSTILSKMSIQGFDVKALRAFRV 194
Query: 233 LRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKV 292
LR L+ V+ VP L+ ++ A++ ++ L + +L +F + ++A++GL+++ G L C+
Sbjct: 195 LRPLRLVSGVPSLQVVLNAILRAMIPLLHIALLVLFVILIYAIIGLELFCGKLHSTCI-- 252
Query: 293 FPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQG-FGPNPN 351
D + G L ++ C +T EG + C S + C P PN
Sbjct: 253 ---DPATGQLAQKD-PTPCGTDT----EGSAFK-CQPSDSLTNMGVRWECSSNTTWPGPN 303
Query: 352 YGYTSFDTFGWAFLSAFRLMTQDYWENLYQ------------LFFVVIIFLGSFYLVNLI 399
G T+FD FG A L+ F+ ++ + W ++ ++FV ++ LGSF+++NL+
Sbjct: 304 NGITNFDNFGLAMLTVFQCVSLEGWTDVMYWVNDAVGREWPWIYFVTLVILGSFFVLNLV 363
Query: 400 LAIVA 404
L +++
Sbjct: 364 LGVLS 368
Score = 115 bits (276), Expect = 2e-23
Identities = 88/312 (28%), Positives = 155/312 (49%), Gaps = 41/312 (13%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQD-ILYYMDRIFTVIFFI 1265
+R ++E FE ++ MI + +ALA+ + ++ +L ++ +F V+F I
Sbjct: 77 IRKLCISIVEWKPFEFLILFMICANCIALAIYQPYPAQDSDYKNTLLETIEYVFIVVFTI 136
Query: 1266 EMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRAL 1321
E ++K +A+GF Y NAW LDFIIV++ L++ + + G K +R R L
Sbjct: 137 ECVLKIVAMGFMFHPSAYLRNAWNILDFIIVVIGLVSTILSKMSIQGFDV-KALRAFRVL 195
Query: 1322 RPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGK-YFKCVDMN 1380
RPLR +S + ++VV+NA+++A+ + ++ L+ L LI+AI+G++LF GK + C+D
Sbjct: 196 RPLRLVSGVPSLQVVLNAILRAMIPLLHIALLVLFVILIYAIIGLELFCGKLHSTCIDPA 255
Query: 1381 HTTLSH---------------EIIPDKNACTL-------ENYTW---ENSPMNFDHVGKA 1415
L+ + P + + N TW N NFD+ G A
Sbjct: 256 TGQLAQKDPTPCGTDTEGSAFKCQPSDSLTNMGVRWECSSNTTWPGPNNGITNFDNFGLA 315
Query: 1416 YLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGV 1475
L +FQ + +GW +M D+ VGR+ + ++Y LNL +GV
Sbjct: 316 MLTVFQCVSLEGWTDVMYWVNDA--VGRE-------WPWIYFVTLVILGSFFVLNLVLGV 366
Query: 1476 IIDNFNEQKKKA 1487
+ F+++++KA
Sbjct: 367 LSGEFSKEREKA 378
Score = 109 bits (263), Expect = 6e-22
Identities = 76/258 (29%), Positives = 134/258 (51%), Gaps = 23/258 (8%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR 1591
+V + F +++L + LN L +T +HY QSE N+ F+++FS E LLK+++L
Sbjct: 469 LVKSQTFYWLVILLVLLNTLVLTSEHYGQSEWLDHFQTMANLFFVILFSMEMLLKMYSLG 528
Query: 1592 Y-HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
+ Y +N FD VV+ SIL VL + + P + V+R A++ R+ ++ K
Sbjct: 529 FTTYTTSQFNRFDCFVVISSILEFVL---VYFDLMKPLGVSVLRSARLLRIFKVTKYWTS 585
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDV--YNFKTFVQS 1708
+R L+ +L SL ++ ++ LLLFL + IFA+ GM F + NF TFVQ+
Sbjct: 586 LRNLVSSLLNSLRSIISLLLLLFLFIVIFALLGMQVFGGKFNFNPQQPKPRANFDTFVQA 645
Query: 1709 MILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISF--- 1765
++ +FQ+ T W+ V+ G G T+G+ + Y+V+
Sbjct: 646 LLTVFQILTGEDWNTVM--------------YHGIESFGGVGTLGVIVCIYYIVLFICGN 691
Query: 1766 LIVINMYIAVILENYSQA 1783
I++N+++A+ ++N + A
Sbjct: 692 YILLNVFLAIAVDNLADA 709
Score = 102 bits (245), Expect = 9e-20
Identities = 123/512 (24%), Positives = 226/512 (44%), Gaps = 67/512 (13%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
+L+++ F VI ++LL++L L E H L + F ++F +EML+K
Sbjct: 468 RLVKSQTFYWLVILLVLLNTLVLTSE--HYGQSEWLDHFQTMANLFFVILFSMEMLLKMY 525
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG 1332
+LGF Y T+ + D +V+ S++ FV +R+ R LR +
Sbjct: 526 SLGFTTYTTSQFNRFDCFVVISSILEFVLVYFDLMKPLGVSVLRSARLLRIFKVTKYWTS 585
Query: 1333 MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDK 1392
+R +V++L+ ++ SI ++LL+ +F +IFA++G+Q+F GK+ + N P
Sbjct: 586 LRNLVSSLLNSLRSIISLLLLLFLFIVIFALLGMQVFGGKF----NFNPQQ------PKP 635
Query: 1393 NACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIY 1452
A NFD +A L +FQ+ T + W +M I+S G + +
Sbjct: 636 RA-------------NFDTFVQALLTVFQILTGEDWNTVMYHGIES--FG--GVGTLGVI 678
Query: 1453 MYLYXXXXXXXXXXXTLNLFIGVIIDNF------------NEQKKKAGGSLEMFMTEDQK 1500
+ +Y LN+F+ + +DN EQ++ G E ED+
Sbjct: 679 VCIYYIVLFICGNYILLNVFLAIAVDNLADADSLTNAEKEEEQQEIEGEDEEFEEGEDEG 738
Query: 1501 KYYNAMKKMGSKKPLKAIPRPRWR----------PQA-IVFEIVTDKKFDMIIMLFIGLN 1549
+ + + G ++ A PR P+A +F + F + + + +
Sbjct: 739 EEHGMDEPEGDEEMTSARPRRMSEVPAASTVKPIPKASSLFILSHTNSFRVFCNMVVNHS 798
Query: 1550 MLT-MTLDHYQQSETFSAVLDYL------NMI---FIVIFSSECLLKIFALRYHYFVEPW 1599
T L S A D L NMI F F+S ++I L+ F +
Sbjct: 799 YFTNAVLFCILVSSAMLAAEDPLQANSTRNMILNYFDYFFTSVFTVEI-TLKVIVFGLVF 857
Query: 1600 NLFDFVVVMFSILSLVLSDIIEKYFVSPT----LLRVVRVAKVGRVLRLVKGAKGIRTLL 1655
+ F F++L +++ + FV T +++++RV +V R LR + AKG++ ++
Sbjct: 858 HKGSFCRNAFNLLDILVVAVSLTSFVLRTDAMSVVKILRVLRVLRPLRAINRAKGLKHVV 917
Query: 1656 FALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+ +++ + NI L+ F++ F+FAI G+ F
Sbjct: 918 QCVIVAVKTIGNIMLVTFMLQFMFAIIGVQLF 949
Score = 86.6 bits (205), Expect = 6e-15
Identities = 52/168 (30%), Positives = 93/168 (55%), Gaps = 12/168 (7%)
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTL-DHY--QQSETFSAVLDYLNMIFIVIFSSECL 1584
+ IV K F+ +I+ I N + + + Y Q S+ + +L+ + +FIV+F+ EC+
Sbjct: 80 LCISIVEWKPFEFLILFMICANCIALAIYQPYPAQDSDYKNTLLETIEYVFIVVFTIECV 139
Query: 1585 LKIFAL--RYH---YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVG 1639
LKI A+ +H Y WN+ DF++V+ ++S +LS K + ++ +R +V
Sbjct: 140 LKIVAMGFMFHPSAYLRNAWNILDFIIVVIGLVSTILS----KMSIQGFDVKALRAFRVL 195
Query: 1640 RVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
R LRLV G ++ +L A+ ++ L +I LL+ V+ I+AI G+ F
Sbjct: 196 RPLRLVSGVPSLQVVLNAILRAMIPLLHIALLVLFVILIYAIIGLELF 243
Score = 77.0 bits (181), Expect = 5e-12
Identities = 47/176 (26%), Positives = 92/176 (52%), Gaps = 11/176 (6%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVEST--------E 170
++L+IL N R ++ H F+ ++ ILV+ ++ ST +
Sbjct: 776 SSLFILSHTNSFRVFCNMVVNHSYFTNAVLFCILVSSAMLAAEDPLQANSTRNMILNYFD 835
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA---L 227
FT ++T E +KV+ G + ++ R+A+N LD +V+A++ + + ++ L
Sbjct: 836 YFFTSVFTVEITLKVIVFGLVFHKGSFCRNAFNLLDILVVAVSLTSFVLRTDAMSVVKIL 895
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
R RVLR L+ + GLK +V VI +VK + +++++T +FA++G+Q++ G
Sbjct: 896 RVLRVLRPLRAINRAKGLKHVVQCVIVAVKTIGNIMLVTFMLQFMFAIIGVQLFKG 951
Score = 65.7 bits (153), Expect = 1e-08
Identities = 39/128 (30%), Positives = 70/128 (54%), Gaps = 6/128 (4%)
Query: 800 FITLCIVVNTLFMALDHHNMDKDMD-KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGA 858
F ++ + L L + ++ K + L+S LR+FK+ K W +L L+S + ++ +
Sbjct: 540 FDCFVVISSILEFVLVYFDLMKPLGVSVLRSARLLRIFKVTKYWTSLRNLVSSLLNSLRS 599
Query: 859 LGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCG 918
+ +L +L + I IFA++GMQ+FG + + P PR NF F+ + + VF++L G
Sbjct: 600 IISLLLLLFLFIVIFALLGMQVFGGKF----NFNPQQPKPRANFDTFVQALLTVFQILTG 655
Query: 919 E-WIESMW 925
E W M+
Sbjct: 656 EDWNTVMY 663
Score = 62.9 bits (146), Expect = 9e-08
Identities = 41/171 (23%), Positives = 86/171 (50%), Gaps = 19/171 (11%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTE-------VIFTGIYT 178
P N ++ + + F I I++N + + P+ E +IFTG++
Sbjct: 1102 PRNRLQYRVWWFVTSRAFEYVIFLIIVMNTVSLACKHYPSSRGFEDFLDVFNLIFTGVFA 1161
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM--------GIDLGNLAALRTF 230
FE+ +K++A L P Y+ D WN D +V+ +++ + G +L ++ R F
Sbjct: 1162 FEAVLKIVA----LNPKNYISDRWNVFDLLVVVGSFIDITYGKLNPGGTNLISINFFRLF 1217
Query: 231 RVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
RV+R +K ++ G++T++ ++S + L V +L + ++A++G+Q +
Sbjct: 1218 RVMRLVKLLSRGEGIRTLLWTFMKSFQALPYVALLIVLLFFIYAVIGMQFF 1268
Score = 51.2 bits (117), Expect = 3e-04
Identities = 33/119 (27%), Positives = 66/119 (55%), Gaps = 10/119 (8%)
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLD-FVVIA--LAYVTMGIDLGN---L 224
+ F +++ E +K+ + GF TY +N D FVVI+ L +V + DL +
Sbjct: 510 LFFVILFSMEMLLKMYSLGFT----TYTTSQFNRFDCFVVISSILEFVLVYFDLMKPLGV 565
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
+ LR+ R+LR K L+ +V +++ S++++ +++L + +FAL+G+Q++ G
Sbjct: 566 SVLRSARLLRIFKVTKYWTSLRNLVSSLLNSLRSIISLLLLLFLFIVIFALLGMQVFGG 624
Score = 48.0 bits (109), Expect = 0.003
Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 5/106 (4%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
+R+ KL + L+ ++ AL + ++ ++ FI+AV+GMQ FGK +D
Sbjct: 1220 MRLVKLLSRGEGIRTLLWTFMKSFQALPYVALLIVLLFFIYAVIGMQFFGKVALDDSTSI 1279
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSCIP 937
+ NF F + +++FR GE W + M C DV C P
Sbjct: 1280 HRNN----NFHSFPAAILVLFRSATGEAWQDIMLSCSDREDVRCDP 1321
Score = 40.7 bits (91), Expect = 0.40
Identities = 24/95 (25%), Positives = 52/95 (54%), Gaps = 4/95 (4%)
Query: 797 VELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTM 856
++ I + +V+T+ + D KAL++ LR +L P+L ++++ + R M
Sbjct: 162 LDFIIVVIGLVSTILSKMSIQGFDV---KALRAFRVLRPLRLVSGVPSLQVVLNAILRAM 218
Query: 857 GALGNLTFVLCIIIFIFAVMGMQLF-GKNYVDYVD 890
L ++ ++ +I I+A++G++LF GK + +D
Sbjct: 219 IPLLHIALLVLFVILIYAIIGLELFCGKLHSTCID 253
>UniRef50_O43497 Cluster: Voltage-dependent T-type calcium channel
subunit alpha-1G; n=70; Euteleostomi|Rep:
Voltage-dependent T-type calcium channel subunit alpha-1G
- Homo sapiens (Human)
Length = 2377
Score = 314 bits (771), Expect = 2e-83
Identities = 186/612 (30%), Positives = 331/612 (54%), Gaps = 44/612 (7%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEM 1267
RL ++I + F+ V+ +I L+ + +A+E + + L + IFT +F EM
Sbjct: 1266 RLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAVFLAEM 1325
Query: 1268 LIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAF---KTMRTLRA 1320
+K +ALG+ Q Y ++W LD ++V++S+I+ + ++ G + + +R LR
Sbjct: 1326 TVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVLRLLRT 1385
Query: 1321 LRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMN 1380
LRPLR +SR QG+++VV L+ ++ I N++++C F++IF I+GVQLF GK+F C
Sbjct: 1386 LRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFVC--QG 1443
Query: 1381 HTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSRE 1440
T + I +K+ C +Y W NFD++G+A + LF +A+ GW+ IM D +D+
Sbjct: 1444 EDTRN---ITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG 1500
Query: 1441 VGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNF-----NEQKKKAGGSLEMFM 1495
V +QPI N +M LY LN+F+GV+++NF ++++++A E +
Sbjct: 1501 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL 1560
Query: 1496 TEDQKKYYNAM--KKMGSKKPLKAIPRPRWRP--------QAIVFEIVTDKKFDMIIMLF 1545
+KK N M + S A + +P + +V + T D+ I
Sbjct: 1561 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV 1620
Query: 1546 IGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDF 1604
IGLN++TM ++HYQQ + L N IF VIF E + K+ A + +F + WN D
Sbjct: 1621 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL 1680
Query: 1605 VVVMFSILSLVLSDI--IEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSL 1662
+V+ SI+ + L +I ++PT++R++RV ++ RVL+L+K A G+R LL + +L
Sbjct: 1681 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL 1740
Query: 1663 PALFNICLLLFLVMFIFAIFGMSFFMHVK-DK----GGLDDVYNFKTFVQSMILLFQMST 1717
P + N+ LL L+ FIFA G+ F ++ D+ GL F+ F + + LF++ST
Sbjct: 1741 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST 1800
Query: 1718 SAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVIL 1777
W+G++ + +CD C + I Y +S+++ + +++N+ IAV++
Sbjct: 1801 GDNWNGIMKDTL--RDCD-------QESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLM 1851
Query: 1778 ENYSQATEDVQE 1789
++ ++ ++ +E
Sbjct: 1852 KHLEESNKEAKE 1863
Score = 105 bits (251), Expect = 2e-20
Identities = 76/274 (27%), Positives = 134/274 (48%), Gaps = 46/274 (16%)
Query: 177 YTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLA--ALRTFRVLR 234
+ E VK++A G I YL D WN LDF ++ + +DL N++ A+RT RVLR
Sbjct: 128 FAVEMVVKMVALG-IFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVRTVRVLR 186
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFP 294
L+ + VP ++ +V +++++ L +V++L F +F ++G+Q++ G+L +C P
Sbjct: 187 PLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRC--FLP 244
Query: 295 EDGSWGNLTD---------------------ENWERFCQNETNWYGEGGDYPLCG----- 328
E+ S D EN R C++ G+GG P CG
Sbjct: 245 ENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGLDYEA 304
Query: 329 -NSSGAGQC---EPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ--- 381
NSS C Y NP G +FD G+A+++ F+++T + W ++
Sbjct: 305 YNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIMYFVM 364
Query: 382 --------LFFVVIIFLGSFYLVNLILAIVAMSY 407
++F+++I +GSF+++NL L ++A +
Sbjct: 365 DAHSFYNFIYFILLIIVGSFFMINLCLVVIATQF 398
Score = 102 bits (244), Expect = 1e-19
Identities = 77/300 (25%), Positives = 137/300 (45%), Gaps = 29/300 (9%)
Query: 1199 PFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRI 1258
P++ + RL L + Y + + +I L+ + +A+E H IL + L + I
Sbjct: 1592 PYYSDYSRFRLLVHHLCTSHYLDLFITGVIGLNVVTMAME--HYQQPQILDEALKICNYI 1649
Query: 1259 FTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGI-----QAFK 1313
FTVIF +E + K +A GF+++F + W LD IV++S++ +
Sbjct: 1650 FTVIFVLESVFKLVAFGFRRFFQDRWNQLDLAIVLLSIMGITLEEIEVNASLPINPTIIR 1709
Query: 1314 TMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
MR LR R L+ + GMR +++ ++QA+P + N+ L+ ++ + IFA +GV+LF
Sbjct: 1710 IMRVLRIARVLKLLKMAVGMRALLDTVMQALPQVGNLGLLFMLLFFIFAALGVELFGD-- 1767
Query: 1374 FKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMN 1433
+C D H P + F + G A+L LF+V+T W IM
Sbjct: 1768 LEC-DETH--------PCEGL---------GRHATFRNFGMAFLTLFRVSTGDNWNGIMK 1809
Query: 1434 DAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEM 1493
D + R+ ++ + +Y +N+ I V++ + E K+A E+
Sbjct: 1810 DTL--RDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKEAKEEAEL 1867
Score = 95.5 bits (227), Expect = 1e-17
Identities = 63/209 (30%), Positives = 108/209 (51%), Gaps = 14/209 (6%)
Query: 1523 WRPQAIVFEIVTDKK-FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSS 1581
WR F + D K F IM+ I +N L+M +++++Q E + L+ N++F +F+
Sbjct: 729 WRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNIVFTSLFAL 788
Query: 1582 ECLLKIFALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGR 1640
E LLK+ + Y P+N+FD V+V+ S+ +V L V+R ++ R
Sbjct: 789 EMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQ--------GGGLSVLRTFRLMR 840
Query: 1641 VLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSF----FMHVKDKGGL 1696
VL+LV+ ++ L L ++ + C+LL L +FIF+I GM F +D L
Sbjct: 841 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL 900
Query: 1697 DDVYNFKTFVQSMILLFQMSTSAGWDGVL 1725
D NF + + +++ +FQ+ T W+ VL
Sbjct: 901 PDRKNFDSLLWAIVTVFQILTQEDWNKVL 929
Score = 94.7 bits (225), Expect = 2e-17
Identities = 59/162 (36%), Positives = 91/162 (56%), Gaps = 13/162 (8%)
Query: 1217 NTYFETAVITMILLSSLALAL----EDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
N +FE + +ILL+ + L + ED+ + IL D F +EM++K +
Sbjct: 80 NPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCR--ILQAFDDFIFAFFAVEMVVKMV 137
Query: 1273 ALG-FQK--YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSR 1329
ALG F K Y + W LDF IV+ ++ + L +F +RT+R LRPLRA++R
Sbjct: 138 ALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNV----SFSAVRTVRVLRPLRAINR 193
Query: 1330 MQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
+ MR++V L+ +P + NVLL+C + IF I+GVQL+AG
Sbjct: 194 VPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 235
Score = 92.3 bits (219), Expect = 1e-16
Identities = 70/297 (23%), Positives = 144/297 (48%), Gaps = 36/297 (12%)
Query: 1521 PRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYL---NMIFIV 1577
P+ R + + I+T K FD ++++ I LN +T+ ++ + + SA +L N IF
Sbjct: 1261 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMER-PKIDPHSAERIFLTLSNYIFTA 1319
Query: 1578 IFSSECLLKIFALRY-----HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRV 1632
+F +E +K+ AL + Y WN+ D ++V+ S++ +++S + + +LRV
Sbjct: 1320 VFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRV 1379
Query: 1633 VRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF----- 1687
+R+ + R LR++ A+G++ ++ L SL + NI ++ IF I G+ F
Sbjct: 1380 LRLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFF 1439
Query: 1688 -------MHVKDKGGLDDV--------YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEE 1732
++ +K + YNF Q+++ LF +++ GW ++ ++
Sbjct: 1440 VCQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAV 1499
Query: 1733 ECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQE 1789
D +P + Y +S+L+I V+NM++ V++EN+ + + +E
Sbjct: 1500 GVDQQPIMNHNPWM-------LLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEE 1549
Score = 79.4 bits (187), Expect = 9e-13
Identities = 47/181 (25%), Positives = 91/181 (50%), Gaps = 20/181 (11%)
Query: 122 WILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVES----------TEV 171
+I P + R + I+ H +F ++ I +NCI + M P ++ +
Sbjct: 1257 YIFPPQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMER-PKIDPHSAERIFLTLSNY 1315
Query: 172 IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID---------LG 222
IFT ++ E VKV+A G+ YLR +WN LD +++ ++ + + + LG
Sbjct: 1316 IFTAVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILG 1375
Query: 223 NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYM 282
L LR R LR L+ ++ GLK +V ++ S+K + +++++ +F ++G+Q++
Sbjct: 1376 MLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFK 1435
Query: 283 G 283
G
Sbjct: 1436 G 1436
Score = 78.2 bits (184), Expect = 2e-12
Identities = 63/272 (23%), Positives = 128/272 (47%), Gaps = 38/272 (13%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
K++++ YF ++ IL+++L++ +E P L + L + +FT +F +EML+K L
Sbjct: 738 KIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEE--LTNALEISNIVFTSLFALEMLLKLL 795
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG 1332
G Y N + D +IV++S+ V GG+ +T R +R L+ +R + +Q
Sbjct: 796 VYGPFGYIKNPYNIFDGVIVVISVWEIVGQQ--GGGLSVLRTFRLMRVLKLVRFLPALQR 853
Query: 1333 MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDK 1392
VV L++ + ++ ++ ++F IF+I+G+ LF K+ D + +PD+
Sbjct: 854 QLVV---LMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERD-------GDTLPDR 903
Query: 1393 NACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIY 1452
NFD + A + +FQ+ T + W +++ + + S T+ +
Sbjct: 904 K--------------NFDSLLWAIVTVFQILTQEDWNKVLYNGMAS----------TSSW 939
Query: 1453 MYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQK 1484
LY NL + ++++ F ++
Sbjct: 940 AALYFIALMTFGNYVLFNLLVAILVEGFQAEE 971
Score = 69.7 bits (163), Expect = 7e-10
Identities = 32/120 (26%), Positives = 72/120 (60%), Gaps = 5/120 (4%)
Query: 163 TPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALA-YVTMGIDL 221
T +E + ++FT ++ E +K++ G PF Y+++ +N D V++ ++ + +G
Sbjct: 772 TNALEISNIVFTSLFALEMLLKLLVYG----PFGYIKNPYNIFDGVIVVISVWEIVGQQG 827
Query: 222 GNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
G L+ LRTFR++R LK V +P L+ + +++++ N+ +L M + +F+++G+ ++
Sbjct: 828 GGLSVLRTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLF 887
Score = 58.0 bits (134), Expect = 2e-06
Identities = 51/174 (29%), Positives = 82/174 (47%), Gaps = 19/174 (10%)
Query: 1524 RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSA------VLDYLNMIFIV 1577
RP++ V + F+ I ML I LN +T+ + ++ E + +L +
Sbjct: 69 RPRSWCLRTVCNPWFERISMLVILLNCVTLGM--FRPCEDIACDSQRCRILQAFDDFIFA 126
Query: 1578 IFSSECLLKIFAL----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVV 1633
F+ E ++K+ AL + Y + WN DF +V+ +L L + VS + +R V
Sbjct: 127 FFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSL----DLQNVSFSAVRTV 182
Query: 1634 RVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
RV R LR + +R L+ L +LP L N+ LL F V FIF I G+ +
Sbjct: 183 RVL---RPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLW 233
Score = 54.0 bits (124), Expect = 4e-05
Identities = 36/118 (30%), Positives = 63/118 (53%), Gaps = 7/118 (5%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L++ +RV KL + P L + ++ +TM + +L + IFIF+++GM LFG +
Sbjct: 833 LRTFRLMRVLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFA 892
Query: 887 DYVDRFPDGD-LP-RWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSCIPFFLA 941
+R DGD LP R NF + + + VF++L E W + +++ M +F+A
Sbjct: 893 S--ER--DGDTLPDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIA 946
Score = 45.6 bits (103), Expect = 0.014
Identities = 31/97 (31%), Positives = 50/97 (51%), Gaps = 4/97 (4%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
RV KL K + L+ + + + +GNL + ++ FIFA +G++LFG D + P
Sbjct: 1718 RVLKLLKMAVGMRALLDTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLECD--ETHP 1775
Query: 894 DGDLPRW-NFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
L R F +F +F+ +FRV G+ W M D +
Sbjct: 1776 CEGLGRHATFRNFGMAFLTLFRVSTGDNWNGIMKDTL 1812
Score = 45.2 bits (102), Expect = 0.018
Identities = 24/92 (26%), Positives = 44/92 (47%), Gaps = 10/92 (10%)
Query: 1395 CTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMY 1454
C+ + +NFD++G A++ +FQV T +GW+ IM +D+ + Y +
Sbjct: 323 CSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIMYFVMDAH----------SFYNF 372
Query: 1455 LYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
+Y +NL + VI F+E K++
Sbjct: 373 IYFILLIIVGSFFMINLCLVVIATQFSETKQR 404
Score = 38.3 bits (85), Expect = 2.1
Identities = 19/77 (24%), Positives = 42/77 (54%), Gaps = 3/77 (3%)
Query: 805 IVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTF 864
++ L +LD N+ A+++ LR + P++ +L++++ T+ LGN+
Sbjct: 160 VIAGMLEYSLDLQNVSFS---AVRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLL 216
Query: 865 VLCIIIFIFAVMGMQLF 881
+ + FIF ++G+QL+
Sbjct: 217 LCFFVFFIFGIVGVQLW 233
Score = 37.1 bits (82), Expect = 4.9
Identities = 21/89 (23%), Positives = 42/89 (47%), Gaps = 1/89 (1%)
Query: 799 LFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGA 858
L + + ++ + M D M + L+ LR ++ L L++ + ++
Sbjct: 1352 LLVLISVIDILVSMVSDSGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLKP 1411
Query: 859 LGNLTFVLCIIIFIFAVMGMQLF-GKNYV 886
+GN+ + C IF ++G+QLF GK +V
Sbjct: 1412 IGNIVVICCAFFIIFGILGVQLFKGKFFV 1440
Score = 36.7 bits (81), Expect = 6.4
Identities = 18/63 (28%), Positives = 36/63 (57%), Gaps = 11/63 (17%)
Query: 356 SFDTFGWAFLSAFRLMTQDYWEN-LYQ----------LFFVVIIFLGSFYLVNLILAIVA 404
+FD+ WA ++ F+++TQ+ W LY L+F+ ++ G++ L NL++AI+
Sbjct: 905 NFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLVAILV 964
Query: 405 MSY 407
+
Sbjct: 965 EGF 967
Score = 36.7 bits (81), Expect = 6.4
Identities = 18/50 (36%), Positives = 31/50 (62%)
Query: 784 FQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYL 833
F+ V L +++LFIT I +N + MA++H+ + +D+ALK NY+
Sbjct: 1600 FRLLVHHLCTSHYLDLFITGVIGLNVVTMAMEHYQQPQILDEALKICNYI 1649
>UniRef50_Q99246 Cluster: Voltage-dependent L-type calcium channel
subunit alpha-1D; n=87; Euteleostomi|Rep:
Voltage-dependent L-type calcium channel subunit alpha-1D
- Mus musculus (Mouse)
Length = 2179
Score = 314 bits (771), Expect = 2e-83
Identities = 213/686 (31%), Positives = 361/686 (52%), Gaps = 52/686 (7%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+R+ KLI + F ++ I+LSS ALA ED H IL Y D FT IF +E
Sbjct: 895 IRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHS-FRNTILGYFDYAFTAIFTVE 953
Query: 1267 MLIKWLALG--FQK--YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALR 1322
+L+K G K + N + LD ++V VSL++F + I K +R LR LR
Sbjct: 954 ILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQ---SSAISVVKILRVLRVLR 1010
Query: 1323 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD---M 1379
PLRA++R +G++ VV + AI +I N+++V + +FA +GVQLF GK+++C D
Sbjct: 1011 PLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKS 1070
Query: 1380 NHTTLSHEII----PDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDA 1435
N I D ++ + W+NS NFD+V A + LF V+TF+GW ++ A
Sbjct: 1071 NPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKA 1130
Query: 1436 IDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFM 1495
IDS P+ + + ++ +N+F+G +I F EQ +K + E+
Sbjct: 1131 IDSNGENVGPVYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDK 1190
Query: 1496 TEDQKKYYNAMKKMGSKKPLKA-IPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMT 1554
+ Q Y A+K +PL+ IP+ + Q + +V F+ ++ + I LN L +
Sbjct: 1191 NQRQCVEY-ALK----ARPLRRYIPKNPY--QYKFWYVVNSSPFEYMMFVLIMLNTLCLA 1243
Query: 1555 LDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR-YHYFVEPWNLFDFVVVMFSILS 1613
+ HY+QS+ F+ +D LNM+F +F+ E +LK+ A + YF + WN FD ++V+ SI+
Sbjct: 1244 MQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIID 1303
Query: 1614 LVLS--DIIEKYFVS-PTL------------LRVVRVAKVGRVLRLVKGAKGIRTLLFAL 1658
+ LS D E + PT + R+ +V R+++L+ +GIRTLL+
Sbjct: 1304 VALSEADPSESETIPLPTATPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTF 1363
Query: 1659 AMSLPALFNICLLLFLVMFIFAIFGMSFF--MHVKDKGGLDDVYNFKTFVQSMILLFQMS 1716
S AL + LL+ ++ FI+A+ GM F + ++D ++ NF+TF Q+++LLF+ +
Sbjct: 1364 IKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCA 1423
Query: 1717 TSAGWDGVLDGIINEEECDLPDNE--RGSPGNCGSATIGITYLLSYLVISFLIVINMYIA 1774
T W ++ + + CD PD++ G CGS I Y +S+ ++ ++IN+++A
Sbjct: 1424 TGEAWQEIMLACLPGKLCD-PDSDYNPGEEYTCGS-NFAIVYFISFYMLCAFLIINLFVA 1481
Query: 1775 VILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHK 1834
VI++N+ T D L D + IW +DP+ I++ + L ++PPL K
Sbjct: 1482 VIMDNFDYLTRD-WSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1540
Query: 1835 --PNKY---KIISMDIPI-CRGDMMF 1854
P++ ++++M++P+ G +MF
Sbjct: 1541 LCPHRVACKRLVAMNMPLNSDGTVMF 1566
Score = 124 bits (300), Expect = 2e-26
Identities = 97/325 (29%), Positives = 162/325 (49%), Gaps = 63/325 (19%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM----------PTTPTVEST 169
AL+ L NPIRR I I+ F +FI+ I NC+ + + T +E
Sbjct: 105 ALFCLSLNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKV 164
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIA-------LAYVTMGIDLG 222
E F I+T E+ +K++A G +L P Y+R+ WN LDFV++ L +T + G
Sbjct: 165 EYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGG 224
Query: 223 N----------LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSV 272
N + ALR FRVLR L+ V+ VP L+ ++ ++I+++ L + +L +F + +
Sbjct: 225 NHSSGKSGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIII 284
Query: 273 FALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSG 332
+A++GL++++G + + C F D ++ E D C S
Sbjct: 285 YAIIGLELFIGKMHKTC---FFAD---SDIVAEE----------------DPAPCAFSGN 322
Query: 333 AGQCEP-GYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWEN-LY---------- 380
QC G C G+ PN G T+FD F +A L+ F+ +T + W + LY
Sbjct: 323 GRQCTANGTECRSGW-VGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAIGWEW 381
Query: 381 -QLFFVVIIFLGSFYLVNLILAIVA 404
++FV +I LGSF+++NL+L +++
Sbjct: 382 PWVYFVSLIILGSFFVLNLVLGVLS 406
Score = 100 bits (240), Expect = 3e-19
Identities = 67/252 (26%), Positives = 129/252 (51%), Gaps = 24/252 (9%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFV 1596
F ++++ + LN LT++ +HY Q + + + D N + + +F+ E L+K+++L YFV
Sbjct: 545 FYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFV 604
Query: 1597 EPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLF 1656
+N FD VV I +L +E +SP + V R ++ R+ ++ + + L+
Sbjct: 605 SLFNRFDCFVVCGGITETIL---VELELMSPLGVSVFRCVRLLRIFKVTRHWTSLSNLVA 661
Query: 1657 ALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVY----NFKTFVQSMILL 1712
+L S+ ++ ++ LLLFL + IF++ GM F K D+ F F Q+++ +
Sbjct: 662 SLLNSMKSIASLLLLLFLFIIIFSLLGMQLF---GGKFNFDETQTKRSTFDNFPQALLTV 718
Query: 1713 FQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINM 1771
FQ+ T W+ V+ DGI+ G P + G I Y + + I++N+
Sbjct: 719 FQILTGEDWNAVMYDGIM----------AYGGPSSSG--MIVCIYFIILFICGNYILLNV 766
Query: 1772 YIAVILENYSQA 1783
++A+ ++N + A
Sbjct: 767 FLAIAVDNLADA 778
Score = 90.2 bits (214), Expect = 5e-16
Identities = 80/311 (25%), Positives = 141/311 (45%), Gaps = 39/311 (12%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALAL-----EDVHLPHRPILQDILYYMDRIFTV 1261
+R ++E F+ ++ I + +ALA+ ED L+ + Y IFTV
Sbjct: 115 IRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTV 174
Query: 1262 IFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALC-----------GAGGIQ 1310
F++++ L L Y N W LDF+IV+V L + + G G
Sbjct: 175 ETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGF 234
Query: 1311 AFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
K +R R LRPLR +S + ++VV+N++++A+ + ++ L+ L +I+AI+G++LF
Sbjct: 235 DVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFI 294
Query: 1371 GKYFK-CVDMNHTTLSHE------IIPDKNACTLENYT----W---ENSPMNFDHVGKAY 1416
GK K C + ++ E + CT W NFD+ A
Sbjct: 295 GKMHKTCFFADSDIVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAM 354
Query: 1417 LCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVI 1476
L +FQ T +GW ++ D+ +G + + ++Y LNL +GV+
Sbjct: 355 LTVFQCITMEGWTDVLYWVNDA--IGWE-------WPWVYFVSLIILGSFFVLNLVLGVL 405
Query: 1477 IDNFNEQKKKA 1487
F+++++KA
Sbjct: 406 SGEFSKEREKA 416
Score = 76.6 bits (180), Expect = 7e-12
Identities = 67/305 (21%), Positives = 134/305 (43%), Gaps = 37/305 (12%)
Query: 1201 WQGWGTL-RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIF 1259
W+ W R + +++ F VI ++ L++L ++ E + P L I +++
Sbjct: 525 WRRWNRFNRRRCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDW--LTQIQDIANKVL 582
Query: 1260 TVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAA---LCGAGGIQAFKTMR 1316
+F EML+K +LG Q YF + + D +V + + L G+ F+ +R
Sbjct: 583 LALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELELMSPLGVSVFRCVR 642
Query: 1317 TLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKC 1376
LR + R + + + V +L+ ++ SI ++LL+ +F +IF+++G+QLF GK+
Sbjct: 643 LLRIFKVTRHWTSLSNL---VASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKF--- 696
Query: 1377 VDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAI 1436
+ + T + FD+ +A L +FQ+ T + W +M D I
Sbjct: 697 -NFDET--------------------QTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGI 735
Query: 1437 DSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMT 1496
+ + + + +Y LN+F+ + +DN + + E
Sbjct: 736 ----MAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEE 791
Query: 1497 EDQKK 1501
+++KK
Sbjct: 792 KERKK 796
Score = 70.9 bits (166), Expect = 3e-10
Identities = 45/176 (25%), Positives = 92/176 (52%), Gaps = 11/176 (6%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT---TPTVEST-----E 170
+A +IL NPIR ++ H +F+ I+ I+++ + + + +T +
Sbjct: 884 SAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFD 943
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTF 230
FT I+T E +K+ G L + R+ +N LD +V+ ++ V+ GI ++ ++
Sbjct: 944 YAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKIL 1003
Query: 231 RVLRALKTVAIV---PGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
RVLR L+ + + GLK +V V +++ + +++I+T +FA +G+Q++ G
Sbjct: 1004 RVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKG 1059
Score = 66.9 bits (156), Expect = 5e-09
Identities = 50/173 (28%), Positives = 87/173 (50%), Gaps = 16/173 (9%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLD---HYQQSETFSAVLDYLNMIFIVIFSSECLLKIF 1588
IV K FD+ I+L I N + + + S + + L+ + F++IF+ E LKI
Sbjct: 122 IVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKII 181
Query: 1589 A--LRYH---YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTL--------LRVVRV 1635
A L H Y WNL DFV+V+ + S++L + ++ ++ +R
Sbjct: 182 AYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALRA 241
Query: 1636 AKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
+V R LRLV G ++ +L ++ ++ L +I LL+ V+ I+AI G+ F+
Sbjct: 242 FRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFI 294
Score = 61.3 bits (142), Expect = 3e-07
Identities = 31/95 (32%), Positives = 56/95 (58%), Gaps = 6/95 (6%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LR+FK+ + W +L+ L++ + +M ++ +L +L + I IF+++GMQLFG + F
Sbjct: 644 LRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKF-----NF 698
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWD 926
+ R F +F + + VF++L GE W M+D
Sbjct: 699 DETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYD 733
Score = 47.2 bits (107), Expect = 0.005
Identities = 41/187 (21%), Positives = 84/187 (44%), Gaps = 35/187 (18%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT-------TPTVESTEVIFTGIYT 178
P NP + Y++ F + I++N + + M ++ ++FTG++T
Sbjct: 1210 PKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFT 1269
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID----------------LG 222
E +KV+A +P Y DAWN D +++ + + + + G
Sbjct: 1270 VEMVLKVIA----FKPKGYFSDAWNTFDSLIVIGSIIDVALSEADPSESETIPLPTATPG 1325
Query: 223 N--------LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFA 274
N + R FRV+R +K ++ G++T++ I+S + L V +L ++A
Sbjct: 1326 NSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYA 1385
Query: 275 LMGLQIY 281
++G+Q++
Sbjct: 1386 VIGMQMF 1392
Score = 43.2 bits (97), Expect = 0.074
Identities = 27/97 (27%), Positives = 50/97 (51%), Gaps = 5/97 (5%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
+R+ KL + L+ ++ AL + ++ ++ FI+AV+GMQ+FGK + ++
Sbjct: 1344 MRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQI 1403
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
+ NF F + +++FR GE W E M C+
Sbjct: 1404 NRNN----NFQTFPQAVLLLFRCATGEAWQEIMLACL 1436
Score = 41.1 bits (92), Expect = 0.30
Identities = 31/118 (26%), Positives = 60/118 (50%), Gaps = 10/118 (8%)
Query: 172 IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLD-FVVIALAYVTMGIDLGNLAAL--- 227
+ ++T E VK+ + G LQ Y +N D FVV T+ ++L ++ L
Sbjct: 581 VLLALFTCEMLVKMYSLG--LQ--AYFVSLFNRFDCFVVCGGITETILVELELMSPLGVS 636
Query: 228 --RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
R R+LR K L +V +++ S+K++ +++L + +F+L+G+Q++ G
Sbjct: 637 VFRCVRLLRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGG 694
Score = 37.5 bits (83), Expect = 3.7
Identities = 16/57 (28%), Positives = 36/57 (63%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
KAL++ LR +L P+L ++++ + + M L ++ ++ +I I+A++G++LF
Sbjct: 237 KALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELF 293
>UniRef50_A7SHI0 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1794
Score = 314 bits (770), Expect = 2e-83
Identities = 194/635 (30%), Positives = 333/635 (52%), Gaps = 43/635 (6%)
Query: 1169 DEDVVD-DTPADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITM 1227
D VD P CC ++ A D+ R+ +L +N +F+ V+
Sbjct: 890 DNPTVDIKVPTSCCSKRADWSLYVFAPDN---------RFRMLNKELYQNKWFDRTVLLF 940
Query: 1228 ILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGF----QKYFTNA 1283
ILL+ + +ALE + + + ++ +F IF IEM++K +ALG Y +
Sbjct: 941 ILLNCVVMALEGPSVLPGSLERRVIDICMYVFLGIFTIEMMVKVIALGLWIGPDAYLRSG 1000
Query: 1284 WCWLDFIIVMVSLINFVAALCGAGG---IQAFKTMRTLRALRPLRAMSRMQGMRVVVNAL 1340
W +D +V++S ++ + G + + R LR LRPLR +SR G+++VV L
Sbjct: 1001 WNVMDGFLVVISWVDVIVTATTNGQNSILGVLRVFRALRTLRPLRVISRAPGLKIVVETL 1060
Query: 1341 VQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENY 1400
+ ++ I N++L+ F++IF I+GVQLF GK+ C D T+ + K C
Sbjct: 1061 ISSLKPIGNIVLIAATFFIIFGILGVQLFKGKFHYCTD---ATVP---VTTKTECLENGG 1114
Query: 1401 TWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXX 1460
+W N NFD++ KA L LF +T GW+ IM D ID+ + +QPIR Y +Y
Sbjct: 1115 SWVNREYNFDNLAKALLTLFVFSTKDGWVNIMYDGIDAVGIDKQPIRNHARYNVIYFVGF 1174
Query: 1461 XXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSK-KPLKAIP 1519
LN+ +GV+++NF +K +EM D++K +KM + +A+
Sbjct: 1175 LLLAGFVVLNMLVGVVVENF----QKCRTLIEMEKKIDEEKKNKKEEKMRREIAEDEALS 1230
Query: 1520 RPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIF 1579
RP+ + + T FD+ I I LN+L M L+HYQQ + +A L N +F +F
Sbjct: 1231 EHYPRPRKFIHAVCTHGYFDLGIAAVIALNVLCMALEHYQQPDGLTAFLKCANYVFTAVF 1290
Query: 1580 SSECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKV 1638
E +LKIFAL Y + WN D ++V+ SI+ + L ++ + ++PT++RV+RV ++
Sbjct: 1291 ILEAILKIFALGIKRYIKDRWNQLDMLIVILSIVGIALEEMTMELPINPTIIRVMRVLRI 1350
Query: 1639 GRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF--MHVKDKG-- 1694
RVL+L+K A+GIR LL +A +LP + N+ +L L+ FIF+ G+ F + + G
Sbjct: 1351 ARVLKLLKTAEGIRKLLDTVAQALPQVGNLGMLFLLMFFIFSALGIELFGKIDCEKPGIT 1410
Query: 1695 --GLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPG-NCGSAT 1751
G+D+ NF++F +M+ LF++ST W+G+L I+ + C R +P +C
Sbjct: 1411 CQGMDEHANFRSFGIAMLTLFRISTGDNWNGILKDTISPDVC------RVNPEIDCSMLE 1464
Query: 1752 -IGITYLLSYLVISFLIVINMYIAVILENYSQATE 1785
+ Y +++ + +++N+ +AV++++ +A +
Sbjct: 1465 HVAPIYFAVFVLATQFVLLNVVVAVLMKHLEEAKD 1499
Score = 85.8 bits (203), Expect = 1e-14
Identities = 49/182 (26%), Positives = 95/182 (52%), Gaps = 18/182 (9%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILM------IMPTT---PTVESTE 170
+L++ P N R + + + F ++ IL+NC++M ++P + ++
Sbjct: 910 SLYVFAPDNRFRMLNKELYQNKWFDRTVLLFILLNCVVMALEGPSVLPGSLERRVIDICM 969
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID---------L 221
+F GI+T E VKV+A G + P YLR WN +D ++ +++V + + L
Sbjct: 970 YVFLGIFTIEMMVKVIALGLWIGPDAYLRSGWNVMDGFLVVISWVDVIVTATTNGQNSIL 1029
Query: 222 GNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
G L R R LR L+ ++ PGLK +V +I S+K + +++++ +F ++G+Q++
Sbjct: 1030 GVLRVFRALRTLRPLRVISRAPGLKIVVETLISSLKPIGNIVLIAATFFIIFGILGVQLF 1089
Query: 282 MG 283
G
Sbjct: 1090 KG 1091
Score = 80.6 bits (190), Expect = 4e-13
Identities = 58/203 (28%), Positives = 102/203 (50%), Gaps = 15/203 (7%)
Query: 1533 VTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR- 1591
V K F +IM I +N LTM +++Y Q + + VL+ N IF IF E ++K+ L
Sbjct: 408 VDSKWFMYVIMGAIFVNTLTMGIEYYGQPQKMTDVLEIFNYIFTAIFGIEMIMKLIGLGF 467
Query: 1592 YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGI 1651
Y Y + +N+FD +V+ S++ L D + + V+R ++ RV +LV+ +
Sbjct: 468 YGYIKDAFNIFDGTIVIISVVELFGDD--------DSGISVLRSFRLLRVFKLVRFLPAL 519
Query: 1652 RTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF----MHVKDKGGLD-DVYNFKTFV 1706
R L + ++ + LL + MF +I GM+ F D+G ++ NF
Sbjct: 520 RRQLLVMIHTMDNVMTFLALLVIFMFTASILGMNLFGGKYRFPNDEGVMETSRANFDDLF 579
Query: 1707 QSMILLFQMSTSAGWDGVL-DGI 1728
+++ +FQ+ T W+ V+ DG+
Sbjct: 580 WAIVTVFQVLTQEDWNIVMYDGM 602
Score = 75.8 bits (178), Expect = 1e-11
Identities = 63/266 (23%), Positives = 120/266 (45%), Gaps = 37/266 (13%)
Query: 1215 IENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLAL 1274
+++ +F ++ I +++L + +E P + + D+L + IFT IF IEM++K + L
Sbjct: 408 VDSKWFMYVIMGAIFVNTLTMGIEYYGQPQK--MTDVLEIFNYIFTAIFGIEMIMKLIGL 465
Query: 1275 GFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMR 1334
GF Y +A+ D IV++S++ GI ++ R LR + +R + ++
Sbjct: 466 GFYGYIKDAFNIFDGTIVIISVVELFGD--DDSGISVLRSFRLLRVFKLVRFLPALRRQL 523
Query: 1335 VVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNA 1394
+V ++ + ++ L + +IF +I+G+ LF GKY P+
Sbjct: 524 LV---MIHTMDNVMTFLALLVIFMFTASILGMNLFGGKY--------------RFPN--- 563
Query: 1395 CTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMY 1454
+ E S NFD + A + +FQV T + W +M D +R T+ +
Sbjct: 564 ---DEGVMETSRANFDDLFWAIVTVFQVLTQEDWNIVMYDG----------MRATSKWAG 610
Query: 1455 LYXXXXXXXXXXXTLNLFIGVIIDNF 1480
LY NL + ++++ F
Sbjct: 611 LYFILLMTIGNYILFNLLVAILVEGF 636
Score = 62.1 bits (144), Expect = 1e-07
Identities = 50/223 (22%), Positives = 101/223 (45%), Gaps = 39/223 (17%)
Query: 224 LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
+ A+R RVLR L+ + VP ++ +V +++++ L +V+ + S+F ++G+Q++ G
Sbjct: 1 MTAVRAIRVLRPLRAINRVPSIRILVTLLLDTLPMLGNVLAMCSLIFSIFGIVGVQMWQG 60
Query: 284 VLTQKC--------------VKVFPEDGSWGNLT----DENWERFCQNE----TNWYGE- 320
VL +C + F + G +L + + ++ C + + +G
Sbjct: 61 VLRSRCVAQLPGNLSANQLNISAFYQPGGSSDLVCSLPENSGDKHCTSAFIPASTAHGRE 120
Query: 321 -GGDYPLCGNSSG----AGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDY 375
G Y N S Y G NP Y SFD A+++ F+++T +
Sbjct: 121 CGLTYEQYSNRSNYTNVCANWNQYYTLCADMGINPLYDAVSFDNILIAWVAIFQVITLEG 180
Query: 376 WENLYQ-----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
W ++ ++FVV+I +GS+++ NL L ++ +
Sbjct: 181 WTDIMYYIQDAHGFWNFIYFVVLIVIGSYFMTNLCLVVITTQF 223
Score = 62.1 bits (144), Expect = 1e-07
Identities = 33/122 (27%), Positives = 67/122 (54%), Gaps = 5/122 (4%)
Query: 163 TPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM-GIDL 221
T +E IFT I+ E +K++ GF + Y++DA+N D ++ ++ V + G D
Sbjct: 440 TDVLEIFNYIFTAIFGIEMIMKLIGLGF----YGYIKDAFNIFDGTIVIISVVELFGDDD 495
Query: 222 GNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
++ LR+FR+LR K V +P L+ + +I ++ N+ + L + + +++G+ ++
Sbjct: 496 SGISVLRSFRLLRVFKLVRFLPALRRQLLVMIHTMDNVMTFLALLVIFMFTASILGMNLF 555
Query: 282 MG 283
G
Sbjct: 556 GG 557
Score = 58.0 bits (134), Expect = 2e-06
Identities = 24/57 (42%), Positives = 41/57 (71%)
Query: 1315 MRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
+R +R LRPLRA++R+ +R++V L+ +P + NVL +C + + IF I+GVQ++ G
Sbjct: 4 VRAIRVLRPLRAINRVPSIRILVTLLLDTLPMLGNVLAMCSLIFSIFGIVGVQMWQG 60
Score = 54.8 bits (126), Expect = 2e-05
Identities = 35/161 (21%), Positives = 77/161 (47%), Gaps = 20/161 (12%)
Query: 137 ILVHPLFSLFIITTILVNCILMIMP-------TTPTVESTEVIFTGIYTFESAVKVMARG 189
+ H F L I I +N + M + T ++ +FT ++ E+ +K+ A G
Sbjct: 1243 VCTHGYFDLGIAAVIALNVLCMALEHYQQPDGLTAFLKCANYVFTAVFILEAILKIFALG 1302
Query: 190 FILQPFTYLRDAWNWLDFVV-------IALAYVTMGIDLGN--LAALRTFRVLRALKTVA 240
Y++D WN LD ++ IAL +TM + + + +R R+ R LK +
Sbjct: 1303 IK----RYIKDRWNQLDMLIVILSIVGIALEEMTMELPINPTIIRVMRVLRIARVLKLLK 1358
Query: 241 IVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
G++ ++ V +++ + ++ +L + +F+ +G++++
Sbjct: 1359 TAEGIRKLLDTVAQALPQVGNLGMLFLLMFFIFSALGIELF 1399
Score = 54.4 bits (125), Expect = 3e-05
Identities = 40/109 (36%), Positives = 59/109 (54%), Gaps = 14/109 (12%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIF--AVMGMQLFGKN 884
L+S LRVFKL + P L + +M TM + +TF+ ++IF+F +++GM LFG
Sbjct: 501 LRSFRLLRVFKLVRFLPALRRQLLVMIHTMDNV--MTFLALLVIFMFTASILGMNLFGGK 558
Query: 885 YVDYVDRFPDG----DLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
Y RFP+ + R NF D + + VF+VL E W M+D M
Sbjct: 559 Y-----RFPNDEGVMETSRANFDDLFWAIVTVFQVLTQEDWNIVMYDGM 602
Score = 46.0 bits (104), Expect = 0.011
Identities = 28/121 (23%), Positives = 61/121 (50%), Gaps = 4/121 (3%)
Query: 803 LCIVVNTLFMALDHHNMDKDMD----KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGA 858
L ++++ + +AL+ M+ ++ + ++ RV KL K+ + L+ + + +
Sbjct: 1317 LIVILSIVGIALEEMTMELPINPTIIRVMRVLRIARVLKLLKTAEGIRKLLDTVAQALPQ 1376
Query: 859 LGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCG 918
+GNL + ++ FIF+ +G++LFGK + G NF F + + +FR+ G
Sbjct: 1377 VGNLGMLFLLMFFIFSALGIELFGKIDCEKPGITCQGMDEHANFRSFGIAMLTLFRISTG 1436
Query: 919 E 919
+
Sbjct: 1437 D 1437
>UniRef50_Q9P0X4 Cluster: Voltage-dependent T-type calcium channel
subunit alpha-1I (Voltage- gated calcium channel subunit
alpha Cav3.3) (Ca(v)3.3); n=39; Euteleostomi|Rep:
Voltage-dependent T-type calcium channel subunit alpha-1I
(Voltage- gated calcium channel subunit alpha Cav3.3)
(Ca(v)3.3) - Homo sapiens (Human)
Length = 2223
Score = 314 bits (770), Expect = 2e-83
Identities = 178/592 (30%), Positives = 319/592 (53%), Gaps = 31/592 (5%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
+I + F+ V+ I L+ + +ALE + + L + IFT IF EM +K ++
Sbjct: 1166 IIAHKLFDYVVLAFIFLNCITIALERPQIEAGSTERIFLTVSNYIFTAIFVGEMTLKVVS 1225
Query: 1274 LGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQ---AFKTMRTLRALRPLRA 1326
LG Q Y ++W LD +V VS+I+ V +L AGG + + +R LR LRPLR
Sbjct: 1226 LGLYFGEQAYLRSSWNVLDGFLVFVSIIDIVVSLASAGGAKILGVLRVLRLLRTLRPLRV 1285
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH 1386
+SR G+++VV L+ ++ I N++L+C F++IF I+GVQLF GK++ C+ ++
Sbjct: 1286 ISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYHCLGVDTRN--- 1342
Query: 1387 EIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPI 1446
I +++ C NY W + NFD++G+A + LF +A+ GW+ IM + +D+ V +QP+
Sbjct: 1343 --ITNRSDCMAANYRWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYNGLDAVAVDQQPV 1400
Query: 1447 RETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAM 1506
N +M LY LN+F+GV+++NF++ ++ E + +
Sbjct: 1401 TNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLEKK 1460
Query: 1507 KKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSA 1566
++ + P A + ++ + T D+ I I LN++TM+L+HY Q +
Sbjct: 1461 RRKAQRLPYYA---TYCHTRLLIHSMCTSHYLDIFITFIICLNVVTMSLEHYNQPTSLET 1517
Query: 1567 VLDYLNMIFIVIFSSECLLKI--FALRYHYFVEPWNLFDFVVVMFSILSLVLSDI-IEKY 1623
L Y N +F +F E +LK+ F LR +F + WN D +V+ S++ + L +I I
Sbjct: 1518 ALKYCNYMFTTVFVLEAVLKLVAFGLR-RFFKDRWNQLDLAIVLLSVMGITLEEIEINAA 1576
Query: 1624 F-VSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIF 1682
++PT++R++RV ++ RVL+L+K A G+R LL + +LP + N+ LL L+ FI+A
Sbjct: 1577 LPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAAL 1636
Query: 1683 GMSFF--MHVKDKG---GLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLP 1737
G+ F + D+ G+ F+ F + + LFQ+ST W+G++ + D
Sbjct: 1637 GVELFGKLVCNDENPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLR----DCT 1692
Query: 1738 DNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQE 1789
+ER + + Y +S+++ + ++IN+ +AV++++ + ++ QE
Sbjct: 1693 HDERSCLSSL--QFVSPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQE 1742
Score = 99.5 bits (237), Expect = 8e-19
Identities = 73/280 (26%), Positives = 138/280 (49%), Gaps = 33/280 (11%)
Query: 1523 WRP-QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSS 1581
WR +A + IV K F+ IM+ I +N ++M ++H++Q E + +L+ N++F +F+
Sbjct: 626 WRETRAKLRGIVDSKYFNRGIMMAILVNTVSMGIEHHEQPEELTNILEICNVVFTSMFAL 685
Query: 1582 ECLLKIFAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGR 1640
E +LK+ A + Y P+N+FD ++V+ SI +V + L V+R ++ R
Sbjct: 686 EMILKLAAFGLFDYLRNPYNIFDSIIVIISIWEIVGQ--------ADGGLSVLRTFRLLR 737
Query: 1641 VLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF-----MHVKDKGG 1695
VL+LV+ +R L L ++ + C+LL L +FIF+I GM F +
Sbjct: 738 VLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDTGDT 797
Query: 1696 LDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGIT 1755
+ D NF + + +++ +FQ+ T W+ VL G ++
Sbjct: 798 VPDRKNFDSLLWAIVTVFQILTQEDWNVVLYN-----------------GMASTSPWASL 840
Query: 1756 YLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDD 1795
Y ++ + ++ N+ +A+++E + QA D +D+D
Sbjct: 841 YFVALMTFGNYVLFNLLVAILVEGF-QAEGDANRSYSDED 879
Score = 97.5 bits (232), Expect = 3e-18
Identities = 60/165 (36%), Positives = 92/165 (55%), Gaps = 11/165 (6%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQD---ILYYMDRIFTVIFFIEMLI 1269
K++ N +FE + +ILL+ + L + L D IL D + F +EM++
Sbjct: 74 KMVCNPWFECVSMLVILLNCVTLGMYQP-CDDMDCLSDRCKILQVFDDFIFIFFAMEMVL 132
Query: 1270 KWLALG-FQK--YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
K +ALG F K Y + W LDF IVM ++ + L +RT+R LRPL+A
Sbjct: 133 KMVALGIFGKKCYLGDTWNRLDFFIVMAGMVEYSLDLQNIN----LSAIRTVRVLRPLKA 188
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
++R+ MR++VN L+ +P + NVLL+C + IF I+GVQL+AG
Sbjct: 189 INRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAG 233
Score = 86.6 bits (205), Expect = 6e-15
Identities = 70/296 (23%), Positives = 135/296 (45%), Gaps = 41/296 (13%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W R K ++++ YF ++ IL++++++ +E P L +IL + +FT +F
Sbjct: 626 WRETRAKLRGIVDSKYFNRGIMMAILVNTVSMGIEHHEQPEE--LTNILEICNVVFTSMF 683
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRP 1323
+EM++K A G Y N + D IIV++S+ V GG+ +T R LR L+
Sbjct: 684 ALEMILKLAAFGLFDYLRNPYNIFDSIIVIISIWEIVGQ--ADGGLSVLRTFRLLRVLKL 741
Query: 1324 LRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTT 1383
+R M ++ VV L++ + ++ ++ ++F IF+I+G+ +F K+ D T
Sbjct: 742 VRFMPALRRQLVV---LMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDTGDT- 797
Query: 1384 LSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGR 1443
+PD+ NFD + A + +FQ+ T + W ++ + + S
Sbjct: 798 -----VPDRK--------------NFDSLLWAIVTVFQILTQEDWNVVLYNGMAS----- 833
Query: 1444 QPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQ 1499
T+ + LY NL + ++++ F + G + + EDQ
Sbjct: 834 -----TSPWASLYFVALMTFGNYVLFNLLVAILVEGFQAE----GDANRSYSDEDQ 880
Score = 85.4 bits (202), Expect = 1e-14
Identities = 57/183 (31%), Positives = 94/183 (51%), Gaps = 20/183 (10%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVE--STE------- 170
++++ P N R + I+ H LF ++ I +NCI + + P +E STE
Sbjct: 1149 SVYLFSPENRFRVLCQTIIAHKLFDYVVLAFIFLNCITIALER-PQIEAGSTERIFLTVS 1207
Query: 171 -VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLD----FV-----VIALAYVTMGID 220
IFT I+ E +KV++ G YLR +WN LD FV V++LA
Sbjct: 1208 NYIFTAIFVGEMTLKVVSLGLYFGEQAYLRSSWNVLDGFLVFVSIIDIVVSLASAGGAKI 1267
Query: 221 LGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
LG L LR R LR L+ ++ PGLK +V +I S+K + +++++ +F ++G+Q+
Sbjct: 1268 LGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQL 1327
Query: 281 YMG 283
+ G
Sbjct: 1328 FKG 1330
Score = 83.0 bits (196), Expect = 7e-14
Identities = 53/172 (30%), Positives = 91/172 (52%), Gaps = 14/172 (8%)
Query: 131 RRVAIYILVHPLFSLFIITTILVNCIL--MIMPT------TPTVESTEVIFTGIYTF--- 179
R I ++ +P F + IL+NC+ M P + + +V I+ F
Sbjct: 69 RNWCIKMVCNPWFECVSMLVILLNCVTLGMYQPCDDMDCLSDRCKILQVFDDFIFIFFAM 128
Query: 180 ESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN--LAALRTFRVLRALK 237
E +K++A G I YL D WN LDF ++ V +DL N L+A+RT RVLR LK
Sbjct: 129 EMVLKMVALG-IFGKKCYLGDTWNRLDFFIVMAGMVEYSLDLQNINLSAIRTVRVLRPLK 187
Query: 238 TVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKC 289
+ VP ++ +V +++++ L +V++L F +F ++G+Q++ G+L +C
Sbjct: 188 AINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRC 239
Score = 71.7 bits (168), Expect = 2e-10
Identities = 49/174 (28%), Positives = 91/174 (52%), Gaps = 13/174 (7%)
Query: 117 ATNALWIL-DPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMP-------TTPTVES 168
A A+W+ D + R I+ F+ I+ ILVN + M + T +E
Sbjct: 615 ADGAVWLCGDVWRETRAKLRGIVDSKYFNRGIMMAILVNTVSMGIEHHEQPEELTNILEI 674
Query: 169 TEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALA-YVTMGIDLGNLAAL 227
V+FT ++ E +K+ A G F YLR+ +N D +++ ++ + +G G L+ L
Sbjct: 675 CNVVFTSMFALEMILKLAAFGL----FDYLRNPYNIFDSIIVIISIWEIVGQADGGLSVL 730
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
RTFR+LR LK V +P L+ + +++++ N+ +L M + +F+++G+ I+
Sbjct: 731 RTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIF 784
Score = 60.1 bits (139), Expect = 6e-07
Identities = 50/173 (28%), Positives = 82/173 (47%), Gaps = 19/173 (10%)
Query: 1525 PQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMI-----FIVIF 1579
P+ ++V + F+ + ML I LN +T+ + YQ + + D ++ FI IF
Sbjct: 68 PRNWCIKMVCNPWFECVSMLVILLNCVTLGM--YQPCDDMDCLSDRCKILQVFDDFIFIF 125
Query: 1580 -SSECLLKIFAL----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVR 1634
+ E +LK+ AL + Y + WN DF +VM ++ L + L +R
Sbjct: 126 FAMEMVLKMVALGIFGKKCYLGDTWNRLDFFIVMAGMVEYSLD-------LQNINLSAIR 178
Query: 1635 VAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+V R L+ + +R L+ L +LP L N+ LL F V FIF I G+ +
Sbjct: 179 TVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLW 231
Score = 52.0 bits (119), Expect = 2e-04
Identities = 30/96 (31%), Positives = 50/96 (52%), Gaps = 7/96 (7%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY- 885
L++ LRV KL + P L + ++ +TM + +L + IFIF+++GM +FG +
Sbjct: 730 LRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFS 789
Query: 886 --VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE 919
D D PD R NF + + + VF++L E
Sbjct: 790 LRTDTGDTVPD----RKNFDSLLWAIVTVFQILTQE 821
Score = 48.0 bits (109), Expect = 0.003
Identities = 28/113 (24%), Positives = 53/113 (46%), Gaps = 14/113 (12%)
Query: 1393 NACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIY 1452
N C + +NFD++G A++ +FQV T +GW++IM +D+ + Y
Sbjct: 324 NVCRTGSANPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAH----------SFY 373
Query: 1453 MYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNA 1505
++Y +NL + VI F+E K++ M E +++Y ++
Sbjct: 374 NFIYFILLIIVGSFFMINLCLVVIATQFSETKQRE----HRLMLEQRQRYLSS 422
Score = 47.2 bits (107), Expect = 0.005
Identities = 24/78 (30%), Positives = 46/78 (58%), Gaps = 12/78 (15%)
Query: 341 VCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYW-ENLYQ----------LFFVVIIF 389
VC G NP+ G +FD G+A++ F+++T + W E +Y ++F+++I
Sbjct: 325 VCRTG-SANPHKGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFILLII 383
Query: 390 LGSFYLVNLILAIVAMSY 407
+GSF+++NL L ++A +
Sbjct: 384 VGSFFMINLCLVVIATQF 401
Score = 44.8 bits (101), Expect = 0.024
Identities = 29/97 (29%), Positives = 51/97 (52%), Gaps = 4/97 (4%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
RV KL K + L+ + + + +GNL + ++ FI+A +G++LFGK + D P
Sbjct: 1594 RVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCN--DENP 1651
Query: 894 -DGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
+G F +F +F+ +F+V G+ W M D +
Sbjct: 1652 CEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTL 1688
Score = 39.1 bits (87), Expect = 1.2
Identities = 16/56 (28%), Positives = 34/56 (60%)
Query: 826 ALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
A+++ LR K P++ +L++++ T+ LGN+ + + FIF ++G+QL+
Sbjct: 176 AIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLW 231
Score = 38.3 bits (85), Expect = 2.1
Identities = 17/54 (31%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF-GKNY 885
LR ++ P L L++ + ++ +GN+ + C IF ++G+QLF GK Y
Sbjct: 1280 LRPLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIFGILGVQLFKGKFY 1333
Score = 37.5 bits (83), Expect = 3.7
Identities = 14/38 (36%), Positives = 26/38 (68%)
Query: 796 FVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYL 833
++++FIT I +N + M+L+H+N ++ ALK NY+
Sbjct: 1488 YLDIFITFIICLNVVTMSLEHYNQPTSLETALKYCNYM 1525
>UniRef50_Q01668 Cluster: Voltage-dependent L-type calcium channel
subunit alpha-1D; n=80; Coelomata|Rep: Voltage-dependent
L-type calcium channel subunit alpha-1D - Homo sapiens
(Human)
Length = 2161
Score = 314 bits (770), Expect = 2e-83
Identities = 214/685 (31%), Positives = 358/685 (52%), Gaps = 50/685 (7%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+R+ KLI + F ++ I+LSS ALA ED H IL Y D FT IF +E
Sbjct: 875 IRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHS-FRNTILGYFDYAFTAIFTVE 933
Query: 1267 MLIKWLALG--FQK--YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALR 1322
+L+K G K + N + LD ++V VSL++F + I K +R LR LR
Sbjct: 934 ILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQ---SSAISVVKILRVLRVLR 990
Query: 1323 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD---M 1379
PLRA++R +G++ VV + AI +I N+++V + +FA +GVQLF GK+++C D
Sbjct: 991 PLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKS 1050
Query: 1380 NHTTLSHEII----PDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDA 1435
N I D ++ + W+NS NFD+V A + LF V+TF+GW ++ A
Sbjct: 1051 NPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKA 1110
Query: 1436 IDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFM 1495
IDS PI + + ++ +N+F+G +I F EQ +K + E+
Sbjct: 1111 IDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDK 1170
Query: 1496 TEDQKKYYNAMKKMGSKKPLKA-IPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMT 1554
+ Q Y A+K +PL+ IP+ + Q + +V F+ ++ + I LN L +
Sbjct: 1171 NQRQCVEY-ALK----ARPLRRYIPKNPY--QYKFWYVVNSSPFEYMMFVLIMLNTLCLA 1223
Query: 1555 LDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR-YHYFVEPWNLFDFVVVMFSILS 1613
+ HY+QS+ F+ +D LNM+F +F+ E +LK+ A + YF + WN FD ++V+ SI+
Sbjct: 1224 MQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIID 1283
Query: 1614 LVLS--DIIEKYFVS-PTL------------LRVVRVAKVGRVLRLVKGAKGIRTLLFAL 1658
+ LS D E V PT + R+ +V R+++L+ +GIRTLL+
Sbjct: 1284 VALSEADPTESENVPVPTATPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTF 1343
Query: 1659 AMSLPALFNICLLLFLVMFIFAIFGMSFF--MHVKDKGGLDDVYNFKTFVQSMILLFQMS 1716
S AL + LL+ ++ FI+A+ GM F + ++D ++ NF+TF Q+++LLF+ +
Sbjct: 1344 IKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCA 1403
Query: 1717 TSAGWDGVLDGIINEEECD-LPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAV 1775
T W ++ + + CD D G CGS I Y +S+ ++ ++IN+++AV
Sbjct: 1404 TGEAWQEIMLACLPGKLCDPESDYNPGEEYTCGS-NFAIVYFISFYMLCAFLIINLFVAV 1462
Query: 1776 ILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHK- 1834
I++N+ T D L D + IW +DP+ I++ + L ++PPL K
Sbjct: 1463 IMDNFDYLTRD-WSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKL 1521
Query: 1835 -PNKY---KIISMDIPI-CRGDMMF 1854
P++ ++++M++P+ G +MF
Sbjct: 1522 CPHRVACKRLVAMNMPLNSDGTVMF 1546
Score = 124 bits (299), Expect = 2e-26
Identities = 96/325 (29%), Positives = 161/325 (49%), Gaps = 63/325 (19%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM----------PTTPTVEST 169
AL+ L NPIRR I I+ F +FI+ I NC+ + + T +E
Sbjct: 105 ALFCLSLNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKV 164
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIA-------LAYVTMGIDLG 222
E F I+T E+ +K++A G +L P Y+R+ WN LDFV++ L +T + G
Sbjct: 165 EYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGG 224
Query: 223 N----------LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSV 272
N + ALR FRVLR L+ V+ VP L+ ++ ++I+++ L + +L +F + +
Sbjct: 225 NHSSGKSGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIII 284
Query: 273 FALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSG 332
+A++GL++++G + + C F D ++ E D C S
Sbjct: 285 YAIIGLELFIGKMHKTC---FFAD---SDIVAEE----------------DPAPCAFSGN 322
Query: 333 AGQCEP-GYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQD------YWEN------L 379
QC G C G+ PN G T+FD F +A L+ F+ +T + YW N L
Sbjct: 323 GRQCTANGTECRSGW-VGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWMNDAMGFEL 381
Query: 380 YQLFFVVIIFLGSFYLVNLILAIVA 404
++FV ++ GSF+++NL+L +++
Sbjct: 382 PWVYFVSLVIFGSFFVLNLVLGVLS 406
Score = 101 bits (241), Expect = 3e-19
Identities = 67/252 (26%), Positives = 129/252 (51%), Gaps = 24/252 (9%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFV 1596
F ++++ + LN LT++ +HY Q + + + D N + + +F+ E L+K+++L YFV
Sbjct: 525 FYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYFV 584
Query: 1597 EPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLF 1656
+N FD VV I +L +E +SP + V R ++ R+ ++ + + L+
Sbjct: 585 SLFNRFDCFVVCGGITETIL---VELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVA 641
Query: 1657 ALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVY----NFKTFVQSMILL 1712
+L S+ ++ ++ LLLFL + IF++ GM F K D+ F F Q+++ +
Sbjct: 642 SLLNSMKSIASLLLLLFLFIIIFSLLGMQLF---GGKFNFDETQTKRSTFDNFPQALLTV 698
Query: 1713 FQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINM 1771
FQ+ T W+ V+ DGI+ G P + G I Y + + I++N+
Sbjct: 699 FQILTGEDWNAVMYDGIM----------AYGGPSSSG--MIVCIYFIILFICGNYILLNV 746
Query: 1772 YIAVILENYSQA 1783
++A+ ++N + A
Sbjct: 747 FLAIAVDNLADA 758
Score = 88.6 bits (210), Expect = 2e-15
Identities = 82/314 (26%), Positives = 139/314 (44%), Gaps = 45/314 (14%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALAL-----EDVHLPHRPILQDILYYMDRIFTV 1261
+R ++E F+ ++ I + +ALA+ ED L+ + Y IFTV
Sbjct: 115 IRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTV 174
Query: 1262 IFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALC-----------GAGGIQ 1310
F++++ L L Y N W LDF+IV+V L + + G G
Sbjct: 175 ETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGF 234
Query: 1311 AFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
K +R R LRPLR +S + ++VV+N++++A+ + ++ L+ L +I+AI+G++LF
Sbjct: 235 DVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFI 294
Query: 1371 GKYFK-CVDMNHTTLSHE------IIPDKNACTLENYT----W---ENSPMNFDHVGKAY 1416
GK K C + ++ E + CT W NFD+ A
Sbjct: 295 GKMHKTCFFADSDIVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAM 354
Query: 1417 LCLFQVATFKGWIQI---MNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFI 1473
L +FQ T +GW + MNDA+ ++Y LNL +
Sbjct: 355 LTVFQCITMEGWTDVLYWMNDAMGFE------------LPWVYFVSLVIFGSFFVLNLVL 402
Query: 1474 GVIIDNFNEQKKKA 1487
GV+ F+++++KA
Sbjct: 403 GVLSGEFSKEREKA 416
Score = 76.2 bits (179), Expect = 9e-12
Identities = 67/305 (21%), Positives = 134/305 (43%), Gaps = 37/305 (12%)
Query: 1201 WQGWGTL-RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIF 1259
W+ W R + +++ F VI ++ L++L ++ E + P L I +++
Sbjct: 505 WRRWNRFNRRRCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDW--LTQIQDIANKVL 562
Query: 1260 TVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAA---LCGAGGIQAFKTMR 1316
+F EML+K +LG Q YF + + D +V + + + GI F+ +R
Sbjct: 563 LALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVR 622
Query: 1317 TLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKC 1376
LR + R + + + V +L+ ++ SI ++LL+ +F +IF+++G+QLF GK+
Sbjct: 623 LLRIFKVTRHWTSLSNL---VASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKF--- 676
Query: 1377 VDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAI 1436
+ + T + FD+ +A L +FQ+ T + W +M D I
Sbjct: 677 -NFDET--------------------QTKRSTFDNFPQALLTVFQILTGEDWNAVMYDGI 715
Query: 1437 DSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMT 1496
+ + + + +Y LN+F+ + +DN + + E
Sbjct: 716 ----MAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKEEAEE 771
Query: 1497 EDQKK 1501
+++KK
Sbjct: 772 KERKK 776
Score = 70.9 bits (166), Expect = 3e-10
Identities = 45/176 (25%), Positives = 92/176 (52%), Gaps = 11/176 (6%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT---TPTVEST-----E 170
+A +IL NPIR ++ H +F+ I+ I+++ + + + +T +
Sbjct: 864 SAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFD 923
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTF 230
FT I+T E +K+ G L + R+ +N LD +V+ ++ V+ GI ++ ++
Sbjct: 924 YAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKIL 983
Query: 231 RVLRALKTVAIV---PGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
RVLR L+ + + GLK +V V +++ + +++I+T +FA +G+Q++ G
Sbjct: 984 RVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKG 1039
Score = 66.9 bits (156), Expect = 5e-09
Identities = 50/173 (28%), Positives = 87/173 (50%), Gaps = 16/173 (9%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLD---HYQQSETFSAVLDYLNMIFIVIFSSECLLKIF 1588
IV K FD+ I+L I N + + + S + + L+ + F++IF+ E LKI
Sbjct: 122 IVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKII 181
Query: 1589 A--LRYH---YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTL--------LRVVRV 1635
A L H Y WNL DFV+V+ + S++L + ++ ++ +R
Sbjct: 182 AYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALRA 241
Query: 1636 AKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
+V R LRLV G ++ +L ++ ++ L +I LL+ V+ I+AI G+ F+
Sbjct: 242 FRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFI 294
Score = 61.3 bits (142), Expect = 3e-07
Identities = 31/95 (32%), Positives = 56/95 (58%), Gaps = 6/95 (6%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LR+FK+ + W +L+ L++ + +M ++ +L +L + I IF+++GMQLFG + F
Sbjct: 624 LRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKF-----NF 678
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWD 926
+ R F +F + + VF++L GE W M+D
Sbjct: 679 DETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYD 713
Score = 47.2 bits (107), Expect = 0.005
Identities = 41/187 (21%), Positives = 84/187 (44%), Gaps = 35/187 (18%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT-------TPTVESTEVIFTGIYT 178
P NP + Y++ F + I++N + + M ++ ++FTG++T
Sbjct: 1190 PKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFT 1249
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID----------------LG 222
E +KV+A +P Y DAWN D +++ + + + + G
Sbjct: 1250 VEMVLKVIA----FKPKGYFSDAWNTFDSLIVIGSIIDVALSEADPTESENVPVPTATPG 1305
Query: 223 N--------LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFA 274
N + R FRV+R +K ++ G++T++ I+S + L V +L ++A
Sbjct: 1306 NSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYA 1365
Query: 275 LMGLQIY 281
++G+Q++
Sbjct: 1366 VIGMQMF 1372
Score = 43.2 bits (97), Expect = 0.074
Identities = 27/97 (27%), Positives = 50/97 (51%), Gaps = 5/97 (5%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
+R+ KL + L+ ++ AL + ++ ++ FI+AV+GMQ+FGK + ++
Sbjct: 1324 MRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQI 1383
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
+ NF F + +++FR GE W E M C+
Sbjct: 1384 NRNN----NFQTFPQAVLLLFRCATGEAWQEIMLACL 1416
Score = 41.1 bits (92), Expect = 0.30
Identities = 31/118 (26%), Positives = 60/118 (50%), Gaps = 10/118 (8%)
Query: 172 IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLD-FVVIALAYVTMGIDLGNLAAL--- 227
+ ++T E VK+ + G LQ Y +N D FVV T+ ++L ++ L
Sbjct: 561 VLLALFTCEMLVKMYSLG--LQ--AYFVSLFNRFDCFVVCGGITETILVELEIMSPLGIS 616
Query: 228 --RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
R R+LR K L +V +++ S+K++ +++L + +F+L+G+Q++ G
Sbjct: 617 VFRCVRLLRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGG 674
Score = 37.5 bits (83), Expect = 3.7
Identities = 16/57 (28%), Positives = 36/57 (63%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
KAL++ LR +L P+L ++++ + + M L ++ ++ +I I+A++G++LF
Sbjct: 237 KALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELF 293
>UniRef50_O60840 Cluster: Voltage-dependent L-type calcium channel
subunit alpha-1F; n=28; Eutheria|Rep: Voltage-dependent
L-type calcium channel subunit alpha-1F - Homo sapiens
(Human)
Length = 1966
Score = 313 bits (769), Expect = 3e-83
Identities = 207/670 (30%), Positives = 352/670 (52%), Gaps = 43/670 (6%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
LR LI + F ++ I+LSS++LA ED H IL Y D FT IF +E
Sbjct: 849 LRKGCHTLIHHHVFTNLILVFIILSSVSLAAEDPIRAHS-FRNHILGYFDYAFTSIFTVE 907
Query: 1267 MLIKWLALG---FQKYFTNAWC-WLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALR 1322
+L+K G + F +W LD ++V VSLI+F + I K +R LR LR
Sbjct: 908 ILLKMTVFGAFLHRGSFCRSWFNMLDLLVVSVSLISFGIH---SSAISVVKILRVLRVLR 964
Query: 1323 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD-MNH 1381
PLRA++R +G++ VV + AI +I N+++V + +FA +GVQLF GK++ C D H
Sbjct: 965 PLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYTCTDEAKH 1024
Query: 1382 TTL----SHEIIPDKNAC--TLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDA 1435
T S + PD + + W NS NFD+V A + LF V+TF+GW ++ A
Sbjct: 1025 TPQECKGSFLVYPDGDVSRPLVRERLWVNSDFNFDNVLSAMMALFTVSTFEGWPALLYKA 1084
Query: 1436 IDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFM 1495
ID+ PI + + ++ +N+F+G +I F Q ++ + E+
Sbjct: 1085 IDAYAEDHGPIYNYRVEISVFFIVYIIIIAFFMMNIFVGFVIITFRAQGEQEYQNCELDK 1144
Query: 1496 TEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTL 1555
+ Q Y A+K +PL+ P+ Q V+ V F+ ++ L I LN + + +
Sbjct: 1145 NQRQCVEY-ALK----AQPLRRY-IPKNPHQYRVWATVNSAAFEYLMFLLILLNTVALAM 1198
Query: 1556 DHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR-YHYFVEPWNLFDFVVVMFSILSL 1614
HY+Q+ F+ +D LNM+F +F+ E +LKI A + HYF + WN FD ++V+ SI+ +
Sbjct: 1199 QHYEQTAPFNYAMDILNMVFTGLFTIEMVLKIIAFKPKHYFTDAWNTFDALIVVGSIVDI 1258
Query: 1615 VLSDIIEKYFV-------SPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFN 1667
++++ + S + R+ +V R+++L+ +GIRTLL+ S AL
Sbjct: 1259 AVTEVNNGGHLGESSEDSSRISITFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPY 1318
Query: 1668 ICLLLFLVMFIFAIFGMSFF--MHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVL 1725
+ LL+ ++ FI+A+ GM F + ++D ++ NF+TF Q+++LLF+ +T W ++
Sbjct: 1319 VALLIAMIFFIYAVIGMQMFGKVALQDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEIM 1378
Query: 1726 DGIINEEECDLPDNERGSPG---NCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQ 1782
+ CD P+++ G PG CGS I Y +S+ ++ ++IN+++AVI++N+
Sbjct: 1379 LASLPGNRCD-PESDFG-PGEEFTCGS-NFAIAYFISFFMLCAFLIINLFVAVIMDNFDY 1435
Query: 1783 ATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHK--PNKY-- 1838
T D L D + IW +DP I++ + L ++PPL K P++
Sbjct: 1436 LTRD-WSILGPHHLDEFKRIWSEYDPGAKGRIKHLDVVALLRRIQPPLGFGKLCPHRVAC 1494
Query: 1839 -KIISMDIPI 1847
++++M++P+
Sbjct: 1495 KRLVAMNMPL 1504
Score = 123 bits (297), Expect = 4e-26
Identities = 88/324 (27%), Positives = 162/324 (50%), Gaps = 61/324 (18%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILM--IMP--------TTPTVEST 169
AL+ L NP+RR I I+ F + I+ TI NC+ + +P +E
Sbjct: 71 ALFCLTLANPLRRSCISIVEWKPFDILILLTIFANCVALGVYIPFPEDDSNTANHNLEQV 130
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLG------- 222
E +F I+T E+ +K++A G +L P Y+R+ WN LDF+++ + ++ ++ G
Sbjct: 131 EYVFLVIFTVETVLKIVAYGLVLHPSAYIRNGWNLLDFIIVVVGLFSVLLEQGPGRPGDA 190
Query: 223 ----------NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSV 272
++ ALR FRVLR L+ V+ VP L ++ ++++++ L + +L +F + +
Sbjct: 191 PHTGGKPGGFDVKALRAFRVLRPLRLVSGVPSLHIVLNSIMKALVPLLHIALLVLFVIII 250
Query: 273 FALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSG 332
+A++GL++++G + + C + GS D E D C +S
Sbjct: 251 YAIIGLELFLGRMHKTCYFL----GS-----DMEAEE-------------DPSPCASSGS 288
Query: 333 AGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENL---------YQL- 382
C +G P PN G T+FD F +A L+ F+ +T + W ++ Y+L
Sbjct: 289 GRACTLNQTECRGRWPGPNGGITNFDNFFFAMLTVFQCVTMEGWTDVLYWMQDAMGYELP 348
Query: 383 --FFVVIIFLGSFYLVNLILAIVA 404
+FV ++ GSF+++NL+L +++
Sbjct: 349 WVYFVSLVIFGSFFVLNLVLGVLS 372
Score = 87.4 bits (207), Expect = 3e-15
Identities = 82/313 (26%), Positives = 141/313 (45%), Gaps = 43/313 (13%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRP--ILQDILYYMDRIFTVIFF 1264
LR ++E F+ ++ I + +AL + + P L ++ +F VIF
Sbjct: 81 LRRSCISIVEWKPFDILILLTIFANCVALGVY-IPFPEDDSNTANHNLEQVEYVFLVIFT 139
Query: 1265 IEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFV----------AALCGA--GG 1308
+E ++K +A G Y N W LDFIIV+V L + + A G GG
Sbjct: 140 VETVLKIVAYGLVLHPSAYIRNGWNLLDFIIVVVGLFSVLLEQGPGRPGDAPHTGGKPGG 199
Query: 1309 IQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQL 1368
K +R R LRPLR +S + + +V+N++++A+ + ++ L+ L +I+AI+G++L
Sbjct: 200 FDV-KALRAFRVLRPLRLVSGVPSLHIVLNSIMKALVPLLHIALLVLFVIIIYAIIGLEL 258
Query: 1369 FAGKYFKCVDMNHTTLSHEIIPDK-------NACTLENY----TW---ENSPMNFDHVGK 1414
F G+ K + + E P ACTL W NFD+
Sbjct: 259 FLGRMHKTCYFLGSDMEAEEDPSPCASSGSGRACTLNQTECRGRWPGPNGGITNFDNFFF 318
Query: 1415 AYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIG 1474
A L +FQ T +GW ++ D+ +G + ++Y LNL +G
Sbjct: 319 AMLTVFQCVTMEGWTDVLYWMQDA--MGYE-------LPWVYFVSLVIFGSFFVLNLVLG 369
Query: 1475 VIIDNFNEQKKKA 1487
V+ F+++++KA
Sbjct: 370 VLSGEFSKEREKA 382
Score = 87.4 bits (207), Expect = 3e-15
Identities = 56/194 (28%), Positives = 103/194 (53%), Gaps = 12/194 (6%)
Query: 1542 IMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPW-N 1600
++L + LN LT+ +H+ Q + + +Y N + + +F+ E LLK++ L +V + N
Sbjct: 524 VLLLVFLNTLTIASEHHGQPVWLTQIQEYANKVLLCLFTVEMLLKLYGLGPSAYVSSFFN 583
Query: 1601 LFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAM 1660
FD VV IL L +E + P + V+R ++ R+ ++ + + L+ +L
Sbjct: 584 RFDCFVVCGGILETTL---VEVGAMQPLGISVLRCVRLLRIFKVTRHWASLSNLVASLLN 640
Query: 1661 SLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVY----NFKTFVQSMILLFQMS 1716
S+ ++ ++ LLLFL + IF++ GM F K D + F TF Q+++ +FQ+
Sbjct: 641 SMKSIASLLLLLFLFIIIFSLLGMQLF---GGKFNFDQTHTKRSTFDTFPQALLTVFQIL 697
Query: 1717 TSAGWDGVL-DGII 1729
T W+ V+ DGI+
Sbjct: 698 TGEDWNVVMYDGIM 711
Score = 73.7 bits (173), Expect = 5e-11
Identities = 65/273 (23%), Positives = 120/273 (43%), Gaps = 30/273 (10%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
LR + + +++ AV+ ++ L++L +A E H L I Y +++ +F +E
Sbjct: 507 LRARCRRAVKSNACYWAVLLLVFLNTLTIASE--HHGQPVWLTQIQEYANKVLLCLFTVE 564
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
ML+K LG Y ++ + D +V ++ GA +R +R LR +
Sbjct: 565 MLLKLYGLGPSAYVSSFFNRFDCFVVCGGILETTLVEVGAMQPLGISVLRCVRLLRIFKV 624
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH 1386
+ +V +L+ ++ SI ++LL+ +F +IF+++G+QLF GK+ D HT S
Sbjct: 625 TRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKF--NFDQTHTKRS- 681
Query: 1387 EIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPI 1446
FD +A L +FQ+ T + W +M D I + P
Sbjct: 682 ---------------------TFDTFPQALLTVFQILTGEDWNVVMYDGIMAYGGPFFP- 719
Query: 1447 RETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDN 1479
+ + +Y LN+F+ + +DN
Sbjct: 720 ---GMLVCIYFIILFICGNYILLNVFLAIAVDN 749
Score = 71.7 bits (168), Expect = 2e-10
Identities = 44/176 (25%), Positives = 90/176 (51%), Gaps = 11/176 (6%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVEST--------E 170
+A + L NP+R+ ++ H +F+ I+ I+++ + + S +
Sbjct: 838 SAFFCLSQTNPLRKGCHTLIHHHVFTNLILVFIILSSVSLAAEDPIRAHSFRNHILGYFD 897
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA---L 227
FT I+T E +K+ G L ++ R +N LD +V++++ ++ GI ++ L
Sbjct: 898 YAFTSIFTVEILLKMTVFGAFLHRGSFCRSWFNMLDLLVVSVSLISFGIHSSAISVVKIL 957
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
R RVLR L+ + GLK +V V +++ + +++I+T +FA +G+Q++ G
Sbjct: 958 RVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKG 1013
Score = 69.7 bits (163), Expect = 7e-10
Identities = 53/173 (30%), Positives = 89/173 (51%), Gaps = 16/173 (9%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLD---HYQQSETFSAVLDYLNMIFIVIFSSECLLKIF 1588
IV K FD++I+L I N + + + S T + L+ + +F+VIF+ E +LKI
Sbjct: 88 IVEWKPFDILILLTIFANCVALGVYIPFPEDDSNTANHNLEQVEYVFLVIFTVETVLKIV 147
Query: 1589 A--LRYH---YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTL--------LRVVRV 1635
A L H Y WNL DF++V+ + S++L + +P ++ +R
Sbjct: 148 AYGLVLHPSAYIRNGWNLLDFIIVVVGLFSVLLEQGPGRPGDAPHTGGKPGGFDVKALRA 207
Query: 1636 AKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
+V R LRLV G + +L ++ +L L +I LL+ V+ I+AI G+ F+
Sbjct: 208 FRVLRPLRLVSGVPSLHIVLNSIMKALVPLLHIALLVLFVIIIYAIIGLELFL 260
Score = 59.3 bits (137), Expect = 1e-06
Identities = 32/101 (31%), Positives = 56/101 (55%), Gaps = 6/101 (5%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+ LR+FK+ + W +L+ L++ + +M ++ +L +L + I IF+++GMQLFG +
Sbjct: 613 LRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKF- 671
Query: 887 DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWD 926
F R F F + + VF++L GE W M+D
Sbjct: 672 ----NFDQTHTKRSTFDTFPQALLTVFQILTGEDWNVVMYD 708
Score = 56.4 bits (130), Expect = 7e-06
Identities = 45/168 (26%), Positives = 82/168 (48%), Gaps = 27/168 (16%)
Query: 143 FSLFIITTILVNCILMIMP----TTP---TVESTEVIFTGIYTFESAVKVMARGFILQPF 195
F + IL+N + + M T P ++ ++FTG++T E +K++A +P
Sbjct: 1181 FEYLMFLLILLNTVALAMQHYEQTAPFNYAMDILNMVFTGLFTIEMVLKIIA----FKPK 1236
Query: 196 TYLRDAWNWLDFVV-------IALAYVTMGIDLG---------NLAALRTFRVLRALKTV 239
Y DAWN D ++ IA+ V G LG ++ R FRV+R +K +
Sbjct: 1237 HYFTDAWNTFDALIVVGSIVDIAVTEVNNGGHLGESSEDSSRISITFFRLFRVMRLVKLL 1296
Query: 240 AIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQ 287
+ G++T++ I+S + L V +L ++A++G+Q++ V Q
Sbjct: 1297 SKGEGIRTLLWTFIKSFQALPYVALLIAMIFFIYAVIGMQMFGKVALQ 1344
Score = 45.6 bits (103), Expect = 0.014
Identities = 27/107 (25%), Positives = 57/107 (53%), Gaps = 6/107 (5%)
Query: 183 VKVMARGFILQPFTYLRDAWNWLD-FVVIALAYVTMGIDLG-----NLAALRTFRVLRAL 236
V+++ + + L P Y+ +N D FVV T +++G ++ LR R+LR
Sbjct: 563 VEMLLKLYGLGPSAYVSSFFNRFDCFVVCGGILETTLVEVGAMQPLGISVLRCVRLLRIF 622
Query: 237 KTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
K L +V +++ S+K++ +++L + +F+L+G+Q++ G
Sbjct: 623 KVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGG 669
Score = 41.5 bits (93), Expect = 0.23
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 5/93 (5%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
+R+ KL + L+ ++ AL + ++ +I FI+AV+GMQ+FGK + +
Sbjct: 1290 MRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIAMIFFIYAVIGMQMFGKVALQDGTQI 1349
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESM 924
+ NF F + +++FR GE W E M
Sbjct: 1350 NRNN----NFQTFPQAVLLLFRCATGEAWQEIM 1378
Score = 37.5 bits (83), Expect = 3.7
Identities = 15/57 (26%), Positives = 37/57 (64%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
KAL++ LR +L P+L+++++ + + + L ++ ++ +I I+A++G++LF
Sbjct: 203 KALRAFRVLRPLRLVSGVPSLHIVLNSIMKALVPLLHIALLVLFVIIIYAIIGLELF 259
>UniRef50_Q869H2 Cluster: Voltage-dependent non-L-type calcium channel
alpha-1 subunit isoform A; n=3; Bilateria|Rep:
Voltage-dependent non-L-type calcium channel alpha-1
subunit isoform A - Lymnaea stagnalis (Great pond snail)
Length = 2141
Score = 310 bits (760), Expect = 3e-82
Identities = 199/682 (29%), Positives = 350/682 (51%), Gaps = 35/682 (5%)
Query: 1219 YFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQ- 1277
YF+ ++ +I SS+ALA ED + + +IL Y D +FT +F IE+++K + LG
Sbjct: 877 YFDLFIMIVICASSVALAAEDPVIENSR-RNEILNYFDFVFTGVFTIELVLKVIDLGVLL 935
Query: 1278 ---KYFTNAWCWLDFIIVMVSLINFVAA--LCGAG-GIQAFKTMRTLRALRPLRAMSRMQ 1331
Y + W LD +V+ +L+ FV AG + K++R LR LRPL+ ++R+
Sbjct: 936 HPGSYIRDLWNILDATVVICALVAFVFKDKSDSAGKNLNTIKSLRVLRVLRPLKTINRVP 995
Query: 1332 GMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH----- 1386
++ V + +V ++ ++ N+L+V ++F IFA++ VQLF G++F C D + +T
Sbjct: 996 KLKAVFDCVVNSLKNVSNILIVYILFQFIFAVIAVQLFKGRFFYCTDESKSTRDECQGQF 1055
Query: 1387 -EIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQP 1445
E N T+ + W ++D++ A L LF V T +GW ++ ++DS R P
Sbjct: 1056 FEYDGHSNDPTVRDREWLRQDFHYDNIMMAMLTLFTVTTGEGWPSVLKHSMDSTYEDRGP 1115
Query: 1446 IRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNA 1505
+ M L+ +N+F+ +II F EQ + ++ M ++QK+ +
Sbjct: 1116 KPVYRMEMSLFYVVFFIVFPFFFVNIFVALIIITFQEQGENE--LMDQEMDKNQKQCIDF 1173
Query: 1506 MKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFS 1565
+ +K + IP+ + + ++ +V KF+ +M I LN + + + + S+ +
Sbjct: 1174 --AINAKPHCRFIPKNKNSIKYKIWRLVQSSKFEYFVMTLITLNTIVLMMKYDGMSDNYK 1231
Query: 1566 AVLDYLNMIFIVIFSSECLLKIFAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYF 1624
VL LN F V+F+ ECLLKI L +YF +PWN+FDF V+ SI+ +++++ K
Sbjct: 1232 DVLAKLNEGFTVLFTLECLLKIIGLGPRNYFHDPWNVFDFTTVVGSIIDVLITE-FSKRQ 1290
Query: 1625 VSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGM 1684
VS R+ R A R+++L++ IR LL+ S AL +CLL+ ++ FI+AI GM
Sbjct: 1291 VSFGFFRLFRAA---RLVKLLRQGYTIRLLLWTFFQSFKALPYVCLLILMLFFIYAIIGM 1347
Query: 1685 SFFMHVK--DKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECD---LPDN 1739
F +K K ++ NF+TF ++ LLF+ +T W ++ + + CD + D+
Sbjct: 1348 QVFGSIKLDSKTSINRHNNFRTFFSALTLLFRCATGEAWQQIMQSCLAGQPCDPESIRDD 1407
Query: 1740 ERGSPGNCGSAT-IGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDM 1798
+ G T I Y +S++ + +++N+++AVI++N+ T D L D
Sbjct: 1408 DPPDMAESGCGTNIAYMYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRD-SSILGPHHLDE 1466
Query: 1799 YYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHKPNKY-----KIISMDIPICRGDMM 1853
Y +W +DP + I Y + + L +EPP+ K Y K+I M++P+ +
Sbjct: 1467 YVRVWSMYDPKATGRIHYTDMYEMLRNMEPPVGFGKKCPYKLAYRKLIRMNMPVAEDGTV 1526
Query: 1854 FCVDILDALTKDFFARKGNPIE 1875
L AL ++ K P E
Sbjct: 1527 HFTTTLFALIRECLIIKMGPAE 1548
Score = 150 bits (364), Expect = 3e-34
Identities = 100/317 (31%), Positives = 165/317 (52%), Gaps = 43/317 (13%)
Query: 117 ATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM----------PTTPTV 166
+T +L+I N IR+ A I+ F ++ TI+ NCI++ + P +
Sbjct: 43 STRSLFIFSEENFIRKYAKIIIEWGPFEYMVLLTIIANCIVLALEEHLPSQDKTPLALQL 102
Query: 167 ESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM----GIDLG 222
+ TEV F GI+ E+ +K++A GF L +YLR+ WN +DF+V+ ++T+
Sbjct: 103 DDTEVYFLGIFCVEAFLKIVALGFCLHKRSYLRNIWNIMDFIVVVTGFITLFAQGSSTTF 162
Query: 223 NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYM 282
+L LR RVLR LK V+ +P L+ ++ ++I ++ L V +L +F++ +FA++GL+ Y+
Sbjct: 163 DLRTLRAVRVLRPLKLVSGIPSLQVVLKSIIRAMAPLLQVCLLVLFAIVIFAIIGLEFYV 222
Query: 283 GVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLC---GNSSGAGQCEPG 339
GV C K GS D+ +T G+ D C S GA QC+
Sbjct: 223 GVFHNACYK----KGSHTRSEDD-------IDT---GDEDDIRPCLPSSESQGAFQCQVN 268
Query: 340 YVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWEN-LYQ-----------LFFVVI 387
+ PN G TSFD G+A L+ F+ +T + W N LY L+F+ +
Sbjct: 269 ISNCKAGWRGPNAGITSFDNIGYAMLTVFQCITMEGWTNVLYYTNDALGNQFNFLYFIPL 328
Query: 388 IFLGSFYLVNLILAIVA 404
I LGSF+++NL+L +++
Sbjct: 329 IILGSFFMLNLVLGVLS 345
Score = 102 bits (245), Expect = 9e-20
Identities = 58/183 (31%), Positives = 102/183 (55%), Gaps = 19/183 (10%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVEST--------- 169
++++I P NPIRR +++ F LFI+ I + + + P +E++
Sbjct: 854 SSMFIFGPTNPIRRFCHFVVNLRYFDLFIMIVICASSVALAAED-PVIENSRRNEILNYF 912
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV---------TMGID 220
+ +FTG++T E +KV+ G +L P +Y+RD WN LD V+ A V + G +
Sbjct: 913 DFVFTGVFTIELVLKVIDLGVLLHPGSYIRDLWNILDATVVICALVAFVFKDKSDSAGKN 972
Query: 221 LGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
L + +LR RVLR LKT+ VP LK + V+ S+KN+ +++I+ + +FA++ +Q+
Sbjct: 973 LNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVNSLKNVSNILIVYILFQFIFAVIAVQL 1032
Query: 281 YMG 283
+ G
Sbjct: 1033 FKG 1035
Score = 93.1 bits (221), Expect = 7e-17
Identities = 84/319 (26%), Positives = 149/319 (46%), Gaps = 43/319 (13%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDR--IFTVIFFIEMLIKW 1271
+IE FE V+ I+ + + LALE+ HLP + L D F IF +E +K
Sbjct: 63 IIEWGPFEYMVLLTIIANCIVLALEE-HLPSQDKTPLALQLDDTEVYFLGIFCVEAFLKI 121
Query: 1272 LALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAM 1327
+ALGF + Y N W +DFI+V+ I A G+ +T+R +R LRPL+ +
Sbjct: 122 VALGFCLHKRSYLRNIWNIMDFIVVVTGFITLFAQ--GSSTTFDLRTLRAVRVLRPLKLV 179
Query: 1328 SRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK-CVDM-NHTTLS 1385
S + ++VV+ ++++A+ + V L+ L +IFAI+G++ + G + C +HT
Sbjct: 180 SGIPSLQVVLKSIIRAMAPLLQVCLLVLFAIVIFAIIGLEFYVGVFHNACYKKGSHTRSE 239
Query: 1386 HEI-----------IPDKNA-----CTLE------NYTWENSPM-NFDHVGKAYLCLFQV 1422
+I +P + C + + N+ + +FD++G A L +FQ
Sbjct: 240 DDIDTGDEDDIRPCLPSSESQGAFQCQVNISNCKAGWRGPNAGITSFDNIGYAMLTVFQC 299
Query: 1423 ATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNE 1482
T +GW ++ D+ +G Q + +LY LNL +GV+ F +
Sbjct: 300 ITMEGWTNVLYYTNDA--LGNQ-------FNFLYFIPLIILGSFFMLNLVLGVLSGEFAK 350
Query: 1483 QKKKAGGSLEMFMTEDQKK 1501
++++ F Q++
Sbjct: 351 ERERVENRRAFFKLRRQQQ 369
Score = 90.2 bits (214), Expect = 5e-16
Identities = 69/286 (24%), Positives = 139/286 (48%), Gaps = 19/286 (6%)
Query: 1503 YNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSE 1562
+ +MKK + + R R + + +V + F I+++ + LN ++ +HY Q E
Sbjct: 443 FKSMKKRRTTGKCASFWRAEKRFRYSIRRLVKSQLFYWIVIVLVFLNTASVASEHYNQPE 502
Query: 1563 TFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIE 1621
L F+ +F E +K++AL YF +N+FD VV++ SI+ ++ S+
Sbjct: 503 WHVQFLYITEYAFLGLFIFEMSIKMYALGVRMYFQSSFNIFDCVVIVGSIVEVIWSEFKR 562
Query: 1622 KYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAI 1681
++LR +R+ ++ +V R +R L+ +L S+ ++ ++ LLFL + +FA+
Sbjct: 563 GSSFGISVLRALRLLRIFKVTRYWSS---LRNLVISLLSSMRSILSLLFLLFLFIIVFAL 619
Query: 1682 FGMSFF-MHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVL-DGIINEEECDLPDN 1739
GM F + + G + F TF +++ +FQ+ T W+ V+ +GI
Sbjct: 620 LGMQLFGGEMNFEEGRPSAH-FDTFPIALLTVFQILTGEDWNEVMYNGI----------K 668
Query: 1740 ERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATE 1785
G N G +Y + ++ ++N+++A+ ++N + A E
Sbjct: 669 SHGGIENQG--MFYSSYFIVLVLFGNYTLLNVFLAIAVDNLANAQE 712
Score = 87.8 bits (208), Expect = 3e-15
Identities = 68/289 (23%), Positives = 128/289 (44%), Gaps = 32/289 (11%)
Query: 1200 FWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIF 1259
FW+ R +L+++ F VI ++ L++ ++A E + P + LY + F
Sbjct: 458 FWRAEKRFRYSIRRLVKSQLFYWIVIVLVFLNTASVASEHYNQPEWHV--QFLYITEYAF 515
Query: 1260 TVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLR 1319
+F EM IK ALG + YF +++ D ++++ S++ + + G +R LR
Sbjct: 516 LGLFIFEMSIKMYALGVRMYFQSSFNIFDCVVIVGSIVEVIWSEFKRGSSFGISVLRALR 575
Query: 1320 ALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDM 1379
LR + +R +V +L+ ++ SI ++L + +F ++FA++G+QLF G+
Sbjct: 576 LLRIFKVTRYWSSLRNLVISLLSSMRSILSLLFLLFLFIIVFALLGMQLFGGEM------ 629
Query: 1380 NHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSR 1439
N+ +FD A L +FQ+ T + W ++M + I S
Sbjct: 630 -------------------NFEEGRPSAHFDTFPIALLTVFQILTGEDWNEVMYNGIKS- 669
Query: 1440 EVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNF-NEQKKKA 1487
I ++ Y LN+F+ + +DN N Q+ A
Sbjct: 670 ---HGGIENQGMFYSSYFIVLVLFGNYTLLNVFLAIAVDNLANAQELTA 715
Score = 72.5 bits (170), Expect = 1e-10
Identities = 46/161 (28%), Positives = 80/161 (49%), Gaps = 13/161 (8%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHY---QQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY-- 1592
F+ +++L I N + + L+ + Q + LD + F+ IF E LKI AL +
Sbjct: 69 FEYMVLLTIIANCIVLALEEHLPSQDKTPLALQLDDTEVYFLGIFCVEAFLKIVALGFCL 128
Query: 1593 ---HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
Y WN+ DF+VV+ ++L + LR +R +V R L+LV G
Sbjct: 129 HKRSYLRNIWNIMDFIVVVTGFITLFAQGSSTTFD-----LRTLRAVRVLRPLKLVSGIP 183
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHV 1690
++ +L ++ ++ L +CLL+ + IFAI G+ F++ V
Sbjct: 184 SLQVVLKSIIRAMAPLLQVCLLVLFAIVIFAIIGLEFYVGV 224
Score = 59.3 bits (137), Expect = 1e-06
Identities = 37/102 (36%), Positives = 63/102 (61%), Gaps = 9/102 (8%)
Query: 827 LKSGNYLRVFKLAKSWPTL-NLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY 885
L++ LR+FK+ + W +L NL+IS++ +M ++ +L F+L + I +FA++GMQLFG
Sbjct: 571 LRALRLLRIFKVTRYWSSLRNLVISLLS-SMRSILSLLFLLFLFIIVFALLGMQLFGGEM 629
Query: 886 VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWD 926
F +G P +F F + + VF++L GE W E M++
Sbjct: 630 -----NFEEG-RPSAHFDTFPIALLTVFQILTGEDWNEVMYN 665
Score = 54.8 bits (126), Expect = 2e-05
Identities = 35/122 (28%), Positives = 65/122 (53%), Gaps = 12/122 (9%)
Query: 169 TEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM-------GIDL 221
TE F G++ FE ++K+ A G + Y + ++N D VVI + V + G
Sbjct: 511 TEYAFLGLFIFEMSIKMYALGVRM----YFQSSFNIFDCVVIVGSIVEVIWSEFKRGSSF 566
Query: 222 GNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
G ++ LR R+LR K L+ +V +++ S++++ ++ L + VFAL+G+Q++
Sbjct: 567 G-ISVLRALRLLRIFKVTRYWSSLRNLVISLLSSMRSILSLLFLLFLFIIVFALLGMQLF 625
Query: 282 MG 283
G
Sbjct: 626 GG 627
Score = 47.2 bits (107), Expect = 0.005
Identities = 34/151 (22%), Positives = 70/151 (46%), Gaps = 16/151 (10%)
Query: 143 FSLFIITTILVNCILMIMPTTPTVESTEVI-------FTGIYTFESAVKVMARGFILQPF 195
F F++T I +N I+++M ++ + + FT ++T E +K++ G P
Sbjct: 1204 FEYFVMTLITLNTIVLMMKYDGMSDNYKDVLAKLNEGFTVLFTLECLLKIIGLG----PR 1259
Query: 196 TYLRDAWNWLDFVVIALAYVTMGID-----LGNLAALRTFRVLRALKTVAIVPGLKTIVG 250
Y D WN DF + + + + I + R FR R +K + ++ ++
Sbjct: 1260 NYFHDPWNVFDFTTVVGSIIDVLITEFSKRQVSFGFFRLFRAARLVKLLRQGYTIRLLLW 1319
Query: 251 AVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+S K L V +L + ++A++G+Q++
Sbjct: 1320 TFFQSFKALPYVCLLILMLFFIYAIIGMQVF 1350
Score = 44.8 bits (101), Expect = 0.024
Identities = 27/96 (28%), Positives = 49/96 (51%), Gaps = 5/96 (5%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
R+ KL + T+ LL+ ++ AL + ++ ++ FI+A++GMQ+FG +D
Sbjct: 1303 RLVKLLRQGYTIRLLLWTFFQSFKALPYVCLLILMLFFIYAIIGMQVFGSIKLDSKTSIN 1362
Query: 894 DGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
+ NF F + ++FR GE W + M C+
Sbjct: 1363 RHN----NFRTFFSALTLLFRCATGEAWQQIMQSCL 1394
Score = 36.3 bits (80), Expect = 8.5
Identities = 22/78 (28%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 805 IVVNTLFMALDHHNMDKDMD-KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLT 863
IVV T F+ L D + L++ LR KL P+L +++ + R M L +
Sbjct: 144 IVVVTGFITLFAQGSSTTFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIIRAMAPLLQVC 203
Query: 864 FVLCIIIFIFAVMGMQLF 881
++ I IFA++G++ +
Sbjct: 204 LLVLFAIVIFAIIGLEFY 221
>UniRef50_O57483 Cluster: Voltage-dependent L-type calcium channel
subunit alpha-1S; n=4; Coelomata|Rep: Voltage-dependent
L-type calcium channel subunit alpha-1S - Rana
catesbeiana (Bull frog)
Length = 1688
Score = 310 bits (760), Expect = 3e-82
Identities = 206/672 (30%), Positives = 352/672 (52%), Gaps = 46/672 (6%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+R+ ++I T F ++ ILLSS++LA ED P +L +D +FTVIF E
Sbjct: 786 IRVLCHRIINATTFTNFILLFILLSSISLAAEDPIQPES-FRNKVLSKLDIVFTVIFTTE 844
Query: 1267 MLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALR 1322
+++K A G + N++ LD +V VSLI+ + I K +R LR LR
Sbjct: 845 IVLKMTAYGAFLHKGSFCRNSFNILDLSVVGVSLISMGIE---SSAISVVKILRVLRVLR 901
Query: 1323 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHT 1382
PLRA++R +G++ VV L AI +I N++LV + +F+ +GVQLF GK++ C D
Sbjct: 902 PLRAINRAKGLKHVVQCLFVAIKTIGNIVLVTTLLQFMFSCIGVQLFKGKFYSCTDTTKI 961
Query: 1383 TLSH-----EIIPDKNACTLENY--TWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDA 1435
T + D N +E W +S +FD+V + LF ++TF+GW Q++ A
Sbjct: 962 TADECRGYFFVAKDGNPAHMEAVPRVWSHSDFHFDNVLSGMMSLFTISTFEGWPQLLYRA 1021
Query: 1436 IDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFM 1495
IDS PI I + ++ +N+F+G +I F EQ ++ E+
Sbjct: 1022 IDSHAEDMGPIYNYRIEIAVFFIVYIILIAFFMMNIFVGFVIVTFQEQGEQEYKDCELDK 1081
Query: 1496 TEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTL 1555
+ Q Y A+K +PL+ P+ Q ++ +VT F+ ++ I LN +++ +
Sbjct: 1082 NQRQCVQY-ALK----ARPLRRY-IPKNPHQYKIWYVVTSSYFEYLMFFLITLNTISLGM 1135
Query: 1556 DHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSL 1614
HY Q+ FS + D LN+ F IF+ E LK+ A + YF +PWN+FDF++V+ S++ +
Sbjct: 1136 QHYGQTAEFSYMSDILNVAFTGIFTVEMFLKLAAFKAKGYFGDPWNVFDFLIVIGSVIDV 1195
Query: 1615 VLSDI-----------IEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLP 1663
+LS+I E +S T R+ RV R+++L+ +G+RTLL+ S
Sbjct: 1196 ILSEIDTPGIPATPGAEESSRISITFFRLFRVL---RLVKLLSRGEGVRTLLWTFIKSFQ 1252
Query: 1664 ALFNICLLLFLVMFIFAIFGMSFF--MHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGW 1721
AL + LL+ ++ FI+A+ GM F + + D ++ NF+TF Q+++LLF+ +T W
Sbjct: 1253 ALPYVALLIVMLFFIYAVIGMQVFGKIALVDGTHINRNSNFQTFPQAVLLLFRCATGEAW 1312
Query: 1722 DGVLDGIINEEECD-LPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENY 1780
+L + CD + D + G CG+ + Y +S+ ++ ++IN+++AVI++N+
Sbjct: 1313 QEILLACSYGKLCDPMSDFQPGEEYTCGT-SFAYFYFISFYMLCAFLIINLFVAVIMDNF 1371
Query: 1781 SQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHK--PNKY 1838
T D L D + IW +DP+ I++ + L ++PPL K P++
Sbjct: 1372 DYLTRD-WSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRV 1430
Query: 1839 ---KIISMDIPI 1847
+++SM++P+
Sbjct: 1431 ACKRLVSMNMPL 1442
Score = 135 bits (326), Expect = 1e-29
Identities = 99/323 (30%), Positives = 165/323 (51%), Gaps = 58/323 (17%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMI----MP------TTPTVEST 169
AL+ L NP R+ I I+ F + I+ TI NC+ + MP T +E
Sbjct: 30 ALFCLGLQNPFRKFCINIVEWKPFEMIILLTIFANCVALAIFLPMPEDDTNSTNSVLEKV 89
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM------------ 217
E IF I+T ES +K++A GFIL YLR+ WN LDF ++++ ++
Sbjct: 90 EYIFLFIFTIESFLKIVAYGFILHTDAYLRNGWNILDFTIVSVGVFSVLLEQISKLQGLP 149
Query: 218 --GIDLG-NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFA 274
G G N+ ALR FRVLR L+ V+ VP L+ ++ ++I+++ L + +L +F + ++A
Sbjct: 150 APGKSSGFNVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMIPLLHIALLVLFMIIIYA 209
Query: 275 LMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAG 334
++GL+++ G + + C F + + +E P +S+G G
Sbjct: 210 IVGLELFSGKMHKTC--YFKDTDITATVDNEK------------------PAPCSSTGQG 249
Query: 335 -QCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYW-ENLY-----------Q 381
QC +G+ P PN G T FD FG+A L+ ++ +T + W E LY
Sbjct: 250 RQCSINGSECRGWWPGPNNGITHFDNFGFAMLTVYQCITMEGWTEVLYWVNDAIGNEWPW 309
Query: 382 LFFVVIIFLGSFYLVNLILAIVA 404
++FV +I LGSF+++NL+L +++
Sbjct: 310 IYFVSLILLGSFFVLNLVLGVLS 332
Score = 103 bits (246), Expect = 7e-20
Identities = 68/256 (26%), Positives = 134/256 (52%), Gaps = 18/256 (7%)
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL 1590
++V + F ++++ I LN + + +H+ Q ++ + D N + + +F+ E ++KI+AL
Sbjct: 426 DLVKSRFFYWLVIIIILLNTVIIATEHHHQPDSLTKAQDIANEVLLALFTMEMIVKIYAL 485
Query: 1591 RYH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
+ YF+ +N FD VV +L ++L + +SP + V+R ++ R+ ++ +
Sbjct: 486 GFQSYFMSLFNRFDSFVVCTGLLEVML---VASDIMSPLGISVLRCIRLLRIFKITRYWT 542
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLD-DVYNFKTFVQS 1708
+ L+ +L S+ ++ ++ LLLFL M IFA+ GM F D L+ F TF Q+
Sbjct: 543 SLNNLVASLLNSVRSIASLLLLLFLFMIIFALLGMQMFGGKFDFEDLEVRRSTFDTFPQA 602
Query: 1709 MILLFQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLI 1767
+I +FQ+ T W V+ +GI+ G P G + Y + V I
Sbjct: 603 LITVFQILTGEDWTAVMYNGIM----------AYGGPTYSGMSV--CIYFIILFVCGNYI 650
Query: 1768 VINMYIAVILENYSQA 1783
++N+++A+ ++N ++A
Sbjct: 651 LLNVFLAIAVDNLAEA 666
Score = 102 bits (245), Expect = 9e-20
Identities = 91/322 (28%), Positives = 153/322 (47%), Gaps = 48/322 (14%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPI--LQDILYYMDRIFTVIFFIEMLIKW 1271
++E FE ++ I + +ALA+ + +P +L ++ IF IF IE +K
Sbjct: 47 IVEWKPFEMIILLTIFANCVALAIF-LPMPEDDTNSTNSVLEKVEYIFLFIFTIESFLKI 105
Query: 1272 LALGF----QKYFTNAWCWLDFIIVMVSL-------INFVAALCGAGGIQAF--KTMRTL 1318
+A GF Y N W LDF IV V + I+ + L G F K +R
Sbjct: 106 VAYGFILHTDAYLRNGWNILDFTIVSVGVFSVLLEQISKLQGLPAPGKSSGFNVKALRAF 165
Query: 1319 RALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGK-----Y 1373
R LRPLR +S + ++VV+N++++A+ + ++ L+ L +I+AI+G++LF+GK Y
Sbjct: 166 RVLRPLRLVSGVPSLQVVLNSIIKAMIPLLHIALLVLFMIIIYAIVGLELFSGKMHKTCY 225
Query: 1374 FKCVDMNHTTLSHEIIPDKNA-----CTL---ENYTWENSPMN----FDHVGKAYLCLFQ 1421
FK D+ T + + P + C++ E W P N FD+ G A L ++Q
Sbjct: 226 FKDTDITATVDNEKPAPCSSTGQGRQCSINGSECRGWWPGPNNGITHFDNFGFAMLTVYQ 285
Query: 1422 VATFKGWIQIM---NDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIID 1478
T +GW +++ NDAI N + ++Y LNL +GV+
Sbjct: 286 CITMEGWTEVLYWVNDAIG------------NEWPWIYFVSLILLGSFFVLNLVLGVLSG 333
Query: 1479 NFNEQKKKAGGSLEMFMTEDQK 1500
F ++++KA M +Q+
Sbjct: 334 EFTKEREKAKSRGAFQMLREQQ 355
Score = 89.4 bits (212), Expect = 9e-16
Identities = 54/186 (29%), Positives = 100/186 (53%), Gaps = 6/186 (3%)
Query: 1201 WQGWGTL-RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPI-LQDILYYMDRI 1258
W+ W L R K+ L+++ +F VI +ILL+++ +A E H P QDI + +
Sbjct: 413 WRLWHRLLRRKSRDLVKSRFFYWLVIIIILLNTVIIATEHHHQPDSLTKAQDIA---NEV 469
Query: 1259 FTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTL 1318
+F +EM++K ALGFQ YF + + D +V L+ + +R +
Sbjct: 470 LLALFTMEMIVKIYALGFQSYFMSLFNRFDSFVVCTGLLEVMLVASDIMSPLGISVLRCI 529
Query: 1319 RALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKCV 1377
R LR + + +V +L+ ++ SI ++LL+ +F +IFA++G+Q+F GK+ F+ +
Sbjct: 530 RLLRIFKITRYWTSLNNLVASLLNSVRSIASLLLLLFLFMIIFALLGMQMFGGKFDFEDL 589
Query: 1378 DMNHTT 1383
++ +T
Sbjct: 590 EVRRST 595
Score = 80.2 bits (189), Expect = 5e-13
Identities = 48/176 (27%), Positives = 96/176 (54%), Gaps = 11/176 (6%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM--PTTP------TVESTE 170
++ +I P N IR + I+ F+ FI+ IL++ I + P P + +
Sbjct: 775 SSFFIFSPTNKIRVLCHRIINATTFTNFILLFILLSSISLAAEDPIQPESFRNKVLSKLD 834
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA---L 227
++FT I+T E +K+ A G L ++ R+++N LD V+ ++ ++MGI+ ++ L
Sbjct: 835 IVFTVIFTTEIVLKMTAYGAFLHKGSFCRNSFNILDLSVVGVSLISMGIESSAISVVKIL 894
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
R RVLR L+ + GLK +V + ++K + +++++T +F+ +G+Q++ G
Sbjct: 895 RVLRVLRPLRAINRAKGLKHVVQCLFVAIKTIGNIVLVTTLLQFMFSCIGVQLFKG 950
Score = 69.7 bits (163), Expect = 7e-10
Identities = 49/173 (28%), Positives = 96/173 (55%), Gaps = 12/173 (6%)
Query: 1521 PRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETF-SAVLDYLNMIFIVIF 1579
P + + + I+ F I+LFI L+ +++ + Q E+F + VL L+++F VIF
Sbjct: 782 PTNKIRVLCHRIINATTFTNFILLFILLSSISLAAEDPIQPESFRNKVLSKLDIVFTVIF 841
Query: 1580 SSECLLKI-----FALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVR 1634
++E +LK+ F + + +N+ D VV S++S+ IE +S +++++R
Sbjct: 842 TTEIVLKMTAYGAFLHKGSFCRNSFNILDLSVVGVSLISMG----IESSAIS--VVKILR 895
Query: 1635 VAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
V +V R LR + AKG++ ++ L +++ + NI L+ L+ F+F+ G+ F
Sbjct: 896 VLRVLRPLRAINRAKGLKHVVQCLFVAIKTIGNIVLVTTLLQFMFSCIGVQLF 948
Score = 69.3 bits (162), Expect = 1e-09
Identities = 50/170 (29%), Positives = 88/170 (51%), Gaps = 14/170 (8%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLD---HYQQSETFSAVLDYLNMIFIVIFSSECLLKIF 1588
IV K F+MII+L I N + + + + + ++VL+ + IF+ IF+ E LKI
Sbjct: 47 IVEWKPFEMIILLTIFANCVALAIFLPMPEDDTNSTNSVLEKVEYIFLFIFTIESFLKIV 106
Query: 1589 ALRY--H---YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFV------SPTLLRVVRVAK 1637
A + H Y WN+ DF +V + S++L I + + S ++ +R +
Sbjct: 107 AYGFILHTDAYLRNGWNILDFTIVSVGVFSVLLEQISKLQGLPAPGKSSGFNVKALRAFR 166
Query: 1638 VGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
V R LRLV G ++ +L ++ ++ L +I LL+ ++ I+AI G+ F
Sbjct: 167 VLRPLRLVSGVPSLQVVLNSIIKAMIPLLHIALLVLFMIIIYAIVGLELF 216
Score = 60.9 bits (141), Expect = 3e-07
Identities = 42/146 (28%), Positives = 77/146 (52%), Gaps = 10/146 (6%)
Query: 782 LEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKS 841
L FQ Y L F+ F + F+ ++ + +A D M L+ LR+FK+ +
Sbjct: 485 LGFQSYFMSL-FNRF-DSFVVCTGLLEVMLVASDI--MSPLGISVLRCIRLLRIFKITRY 540
Query: 842 WPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWN 901
W +LN L++ + ++ ++ +L +L + + IFA++GMQ+FG + F D ++ R
Sbjct: 541 WTSLNNLVASLLNSVRSIASLLLLLFLFMIIFALLGMQMFGGKF-----DFEDLEVRRST 595
Query: 902 FTDFMHSFMIVFRVLCGE-WIESMWD 926
F F + + VF++L GE W M++
Sbjct: 596 FDTFPQALITVFQILTGEDWTAVMYN 621
Score = 50.0 bits (114), Expect = 6e-04
Identities = 38/167 (22%), Positives = 78/167 (46%), Gaps = 17/167 (10%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMP-------TTPTVESTEVIFTGIYTFESA 182
+RR + ++ F +I IL+N +++ T + + ++T E
Sbjct: 420 LRRKSRDLVKSRFFYWLVIIIILLNTVIIATEHHHQPDSLTKAQDIANEVLLALFTMEMI 479
Query: 183 VKVMARGFILQPFTYLRDAWNWLDFVVIA---LAYVTMGIDLGN---LAALRTFRVLRAL 236
VK+ A GF +Y +N D V+ L + + D+ + ++ LR R+LR
Sbjct: 480 VKIYALGFQ----SYFMSLFNRFDSFVVCTGLLEVMLVASDIMSPLGISVLRCIRLLRIF 535
Query: 237 KTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
K L +V +++ SV+++ +++L + +FAL+G+Q++ G
Sbjct: 536 KITRYWTSLNNLVASLLNSVRSIASLLLLLFLFMIIFALLGMQMFGG 582
Score = 47.6 bits (108), Expect = 0.003
Identities = 46/180 (25%), Positives = 81/180 (45%), Gaps = 28/180 (15%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTT-PTVEST------EVIFTGIYT 178
P NP + Y++ F + I +N I + M T E + V FTGI+T
Sbjct: 1101 PKNPHQYKIWYVVTSSYFEYLMFFLITLNTISLGMQHYGQTAEFSYMSDILNVAFTGIFT 1160
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVI---ALAYVTMGIDLGNLAA--------- 226
E +K+ A + Y D WN DF+++ + + ID + A
Sbjct: 1161 VEMFLKLAA----FKAKGYFGDPWNVFDFLIVIGSVIDVILSEIDTPGIPATPGAEESSR 1216
Query: 227 -----LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
R FRVLR +K ++ G++T++ I+S + L V +L + ++A++G+Q++
Sbjct: 1217 ISITFFRLFRVLRLVKLLSRGEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVF 1276
Score = 40.7 bits (91), Expect = 0.40
Identities = 29/96 (30%), Positives = 48/96 (50%), Gaps = 5/96 (5%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LR+ KL + L+ ++ AL + ++ ++ FI+AV+GMQ+FGK + VD
Sbjct: 1228 LRLVKLLSRGEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGK--IALVDGT 1285
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDC 927
NF F + +++FR GE W E + C
Sbjct: 1286 HIN--RNSNFQTFPQAVLLLFRCATGEAWQEILLAC 1319
Score = 36.3 bits (80), Expect = 8.5
Identities = 16/57 (28%), Positives = 36/57 (63%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
KAL++ LR +L P+L ++++ + + M L ++ ++ +I I+A++G++LF
Sbjct: 160 KALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMIPLLHIALLVLFMIIIYAIVGLELF 216
>UniRef50_P56699 Cluster: Probable voltage-dependent R-type calcium
channel subunit alpha-1E; n=20; Gnathostomata|Rep:
Probable voltage-dependent R-type calcium channel subunit
alpha-1E - Discopyge ommata (Electric ray)
Length = 2223
Score = 309 bits (759), Expect = 5e-82
Identities = 196/654 (29%), Positives = 345/654 (52%), Gaps = 37/654 (5%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
++ YFE ++ +I SS+ALA ED + +L Y D +FT +F EM+IK +
Sbjct: 1101 IVNLRYFEMCILLVIAASSVALAAEDP-IHKDSARNQVLRYFDYVFTGVFTFEMVIKMID 1159
Query: 1274 LGFQ----KYFTNAWCWLDFIIVMVSLINFVAA--LCGAGG--IQAFKTMRTLRALRPLR 1325
+G YF + W LDFI+V +L+ F + G+ G I K++R LR LRPL+
Sbjct: 1160 IGLVFHEGSYFRDVWNILDFIVVSGALVAFAFTNLIGGSSGKDINTIKSLRVLRVLRPLK 1219
Query: 1326 AMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLS 1385
+ R+ ++ V + +V ++ ++FN+L+V +F IFA++ VQLF GK+F C D + T
Sbjct: 1220 TIKRLPKLKAVFDCVVTSLKNVFNILIVYKLFMFIFAVIAVQLFKGKFFYCTDSSKMTKQ 1279
Query: 1386 H---EIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVG 1442
+ + + L + ++D+V A L LF V+T +GW Q++ ++D E
Sbjct: 1280 DCRGQFVLYRQRTKLSIENGNVTTFHYDNVVWALLTLFTVSTGEGWPQVLQHSVDVTEAD 1339
Query: 1443 RQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKY 1502
+ PI + M ++ +N+F+ +II F EQ K LE E ++
Sbjct: 1340 QGPIPGNRMEMSIFYIVYFVVFPFFFVNIFVALIIITFQEQGDK---MLEESSLEKNER- 1395
Query: 1503 YNAMKKMGSKKPL-KAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQS 1561
+ S KPL + +P+ R Q V++ V F+ I+ I LN + + + H+
Sbjct: 1396 -ACIDFAISAKPLTRYMPQNRQTFQYRVWQFVVSPSFEYTILTMIALNTVVLMMKHHSPP 1454
Query: 1562 ETFSAVLDYLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSLVLSDII 1620
F++VL +N+ F + F+ EC+LKI A + +YF + WN+FDFV V+ SI +++++
Sbjct: 1455 PGFASVLKLMNIAFTITFTLECILKIIAFGFLNYFRDSWNVFDFVTVVGSISEIIVTECN 1514
Query: 1621 EKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFA 1680
K FV+ + L++ R A R+++L++ IR LL+ S AL +CLL+ ++ FI+A
Sbjct: 1515 LK-FVNLSFLKLFRAA---RLIKLLRQGITIRILLWTFVQSFKALPYVCLLIAMLFFIYA 1570
Query: 1681 IFGMSFFMHV--KDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPD 1738
I GM F ++ D ++ NF TF +++LLF+ +T W ++ ++ +EC
Sbjct: 1571 IIGMQLFGNIGLDDHTPINRHNNFHTFFNALMLLFRSATGESWQEIMLACLSGKEC---- 1626
Query: 1739 NERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDM 1798
E +CG+ + Y +S++ + +++N+++AVI++N+ T D L D
Sbjct: 1627 -EGTREPSCGT-DVAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRD-SSILGPHHLDE 1683
Query: 1799 YYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHK--PNK--YK-IISMDIPI 1847
+ +W +D I Y + L ++ PPL + K P+K YK ++ M++P+
Sbjct: 1684 FVRVWAEYDRAACGRIHYTDMYQMLTLMSPPLGLGKKCPSKVAYKRLVLMNMPV 1737
Score = 140 bits (339), Expect = 4e-31
Identities = 89/311 (28%), Positives = 158/311 (50%), Gaps = 46/311 (14%)
Query: 116 SATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM----------PTTPT 165
+A +L++ N +R+ A ++ P F I+ TI+ NC+++ + P +
Sbjct: 77 TANRSLFLFGEDNIVRKSARRVIEWPPFEYMILATIIANCVVLALEQHLPNGDKTPMAKS 136
Query: 166 VESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLA 225
+E TE F GI+ FE+ +K++A GF+ +YLR+ WN +DF+V+ + NL
Sbjct: 137 LEQTEPYFIGIFCFEAGIKIVALGFVFHKGSYLRNGWNVMDFIVVLSGLLATAATHFNLR 196
Query: 226 ALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVL 285
LR RVLR LK V+ +P L+ ++ ++++++ L + +L F++ +FA++GL+ Y G L
Sbjct: 197 TLRAVRVLRPLKLVSGIPSLQIVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYYGKL 256
Query: 286 TQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQG 345
+ C + +D + L + +P CG C G VC
Sbjct: 257 HRTC---YTDDAAAEELDLQ------------------FP-CGTQEPTRLCPNGTVCSYW 294
Query: 346 FGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWEN-LYQ-----------LFFVVIIFLGSF 393
GPN G T FD +A L+ F+ +T + W LY L+F+ +I +GSF
Sbjct: 295 IGPND--GITQFDNILFALLTVFQCITMEGWTTILYNTDDALGAMWNWLYFIPLIIIGSF 352
Query: 394 YLVNLILAIVA 404
+++NL+L +++
Sbjct: 353 FVLNLVLGVLS 363
Score = 95.1 bits (226), Expect = 2e-17
Identities = 53/182 (29%), Positives = 97/182 (53%), Gaps = 18/182 (9%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVEST--------EV 171
++++ NPIRRV +I+ F + I+ I + + + +S +
Sbjct: 1084 SMFLFRKTNPIRRVCHFIVNLRYFEMCILLVIAASSVALAAEDPIHKDSARNQVLRYFDY 1143
Query: 172 IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM----------GIDL 221
+FTG++TFE +K++ G + +Y RD WN LDF+V++ A V G D+
Sbjct: 1144 VFTGVFTFEMVIKMIDIGLVFHEGSYFRDVWNILDFIVVSGALVAFAFTNLIGGSSGKDI 1203
Query: 222 GNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+ +LR RVLR LKT+ +P LK + V+ S+KN+ +++I+ + +FA++ +Q++
Sbjct: 1204 NTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVTSLKNVFNILIVYKLFMFIFAVIAVQLF 1263
Query: 282 MG 283
G
Sbjct: 1264 KG 1265
Score = 93.5 bits (222), Expect = 5e-17
Identities = 80/320 (25%), Positives = 144/320 (45%), Gaps = 28/320 (8%)
Query: 1489 GSLEMFMTEDQKKYYNAMKKMGSK------KPLKAIP-----RPRWRPQAI-VFEIVTDK 1536
G +EM TE + Y + +GS K K + R + R I + +V
Sbjct: 431 GRMEMIQTESSEDQYTEISSVGSPLARASIKSTKLLEGSSYFRRKERMLRISIRHMVKSH 490
Query: 1537 KFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YF 1595
F I++ + LN + + + HY Q S L Y F+ +FSSE LK++ YF
Sbjct: 491 AFYWIVLGLVALNTVCVAVVHYDQPLWLSNFLYYAEFTFLGLFSSEMFLKMYGCGPRLYF 550
Query: 1596 VEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLL 1655
+N FD V++ SI +V + I + ++LR +R+ R+ ++ K +R L+
Sbjct: 551 HSSFNCFDCGVIIGSIFDVVWTIIRPETSFGISVLRALRLL---RIFKITKYWASLRNLV 607
Query: 1656 FALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQM 1715
+L S+ ++ ++ LLFL + +FA+ GM F + NF TF ++I +FQ+
Sbjct: 608 VSLMSSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFEEGTPPTNFDTFPAAIITVFQI 667
Query: 1716 STSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAV 1775
T W+ V+ I S G S Y + + ++N+++A+
Sbjct: 668 LTGEDWNEVMYNGIK------------SQGGVNSGMWSSVYFIVLTLFGNYTLLNVFLAI 715
Query: 1776 ILENYSQATEDVQEGLTDDD 1795
++N + A E +E +++
Sbjct: 716 AVDNLANAQELTKEEQEEEE 735
Score = 83.4 bits (197), Expect = 6e-14
Identities = 77/300 (25%), Positives = 144/300 (48%), Gaps = 38/300 (12%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPH--RPILQDILYYMDRIFTVIFF 1264
+R ++IE FE ++ I+ + + LALE HLP+ + + L + F IF
Sbjct: 91 VRKSARRVIEWPPFEYMILATIIANCVVLALEQ-HLPNGDKTPMAKSLEQTEPYFIGIFC 149
Query: 1265 IEMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRA 1320
E IK +ALGF Y N W +DFI+V+ L+ A +T+R +R
Sbjct: 150 FEAGIKIVALGFVFHKGSYLRNGWNVMDFIVVLSGLLATAATHFN------LRTLRAVRV 203
Query: 1321 LRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK-C--- 1376
LRPL+ +S + +++V+ ++++A+ + + L+ L+FAI+G++ + GK + C
Sbjct: 204 LRPLKLVSGIPSLQIVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYYGKLHRTCYTD 263
Query: 1377 ------VDMNHTTLSHE---IIPDKNACTLENYTWENSPM-NFDHVGKAYLCLFQVATFK 1426
+D+ + E + P+ C+ + N + FD++ A L +FQ T +
Sbjct: 264 DAAAEELDLQFPCGTQEPTRLCPNGTVCSY--WIGPNDGITQFDNILFALLTVFQCITME 321
Query: 1427 GWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
GW I+ + D+ +G ++ +LY LNL +GV+ F +++++
Sbjct: 322 GWTTILYNTDDA--LGA-------MWNWLYFIPLIIIGSFFVLNLVLGVLSGEFAKERER 372
Score = 80.2 bits (189), Expect = 5e-13
Identities = 69/311 (22%), Positives = 138/311 (44%), Gaps = 35/311 (11%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
LR+ ++++ F V+ ++ L+++ +A+ VH L + LYY + F +F E
Sbjct: 479 LRISIRHMVKSHAFYWIVLGLVALNTVCVAV--VHYDQPLWLSNFLYYAEFTFLGLFSSE 536
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
M +K G + YF +++ D +++ S+ + V + +R LR LR +
Sbjct: 537 MFLKMYGCGPRLYFHSSFNCFDCGVIIGSIFDVVWTIIRPETSFGISVLRALRLLRIFKI 596
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH 1386
+R +V +L+ ++ SI ++L + +F ++FA++G+QLF G++
Sbjct: 597 TKYWASLRNLVVSLMSSMKSIISLLFLLFLFIVVFALLGMQLFGGQF------------- 643
Query: 1387 EIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPI 1446
N+ P NFD A + +FQ+ T + W ++M + I S Q
Sbjct: 644 ------------NFEEGTPPTNFDTFPAAIITVFQILTGEDWNEVMYNGIKS-----QGG 686
Query: 1447 RETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAM 1506
+ ++ +Y LN+F+ + +DN ++ E +QK +A+
Sbjct: 687 VNSGMWSSVYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKEEQEEEEAINQK---HAL 743
Query: 1507 KKMGSKKPLKA 1517
+K P+ A
Sbjct: 744 QKAKEVSPMSA 754
Score = 65.3 bits (152), Expect = 2e-08
Identities = 39/102 (38%), Positives = 64/102 (62%), Gaps = 9/102 (8%)
Query: 827 LKSGNYLRVFKLAKSWPTL-NLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY 885
L++ LR+FK+ K W +L NL++S+M +M ++ +L F+L + I +FA++GMQLFG +
Sbjct: 585 LRALRLLRIFKITKYWASLRNLVVSLMS-SMKSIISLLFLLFLFIVVFALLGMQLFGGQF 643
Query: 886 VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWD 926
F +G P NF F + + VF++L GE W E M++
Sbjct: 644 -----NFEEG-TPPTNFDTFPAAIITVFQILTGEDWNEVMYN 679
Score = 61.3 bits (142), Expect = 3e-07
Identities = 40/156 (25%), Positives = 78/156 (50%), Gaps = 16/156 (10%)
Query: 138 LVHPLFSLFIITTILVNCILMIMP--TTP-----TVESTEVIFTGIYTFESAVKVMARGF 190
+V P F I+T I +N ++++M + P ++ + FT +T E +K++A GF
Sbjct: 1426 VVSPSFEYTILTMIALNTVVLMMKHHSPPPGFASVLKLMNIAFTITFTLECILKIIAFGF 1485
Query: 191 ILQPFTYLRDAWNWLDFVVIA-----LAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGL 245
+ Y RD+WN DFV + + + NL+ L+ FR R +K + +
Sbjct: 1486 L----NYFRDSWNVFDFVTVVGSISEIIVTECNLKFVNLSFLKLFRAARLIKLLRQGITI 1541
Query: 246 KTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+ ++ ++S K L V +L ++A++G+Q++
Sbjct: 1542 RILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQLF 1577
Score = 59.3 bits (137), Expect = 1e-06
Identities = 44/158 (27%), Positives = 76/158 (48%), Gaps = 17/158 (10%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQS---ETFSAVLDYLNMIFIVIFSSECLLKIFALRY-- 1592
F+ +I+ I N + + L+ + + + L+ FI IF E +KI AL +
Sbjct: 104 FEYMILATIIANCVVLALEQHLPNGDKTPMAKSLEQTEPYFIGIFCFEAGIKIVALGFVF 163
Query: 1593 ---HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
Y WN+ DF+VV+ +L+ + LR +R +V R L+LV G
Sbjct: 164 HKGSYLRNGWNVMDFIVVLSGLLATAATHFN---------LRTLRAVRVLRPLKLVSGIP 214
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
++ +L ++ ++ L I LLLF + +FAI G+ F+
Sbjct: 215 SLQIVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFY 252
Score = 50.4 bits (115), Expect = 5e-04
Identities = 33/103 (32%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
LK R+ KL + T+ +L+ ++ AL + ++ ++ FI+A++GMQLFG +
Sbjct: 1523 LKLFRAARLIKLLRQGITIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQLFGNIGL 1582
Query: 887 DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
D D P NF F ++ M++FR GE W E M C+
Sbjct: 1583 D--DHTPIN--RHNNFHTFFNALMLLFRSATGESWQEIMLACL 1621
Score = 42.7 bits (96), Expect = 0.098
Identities = 30/120 (25%), Positives = 59/120 (49%), Gaps = 10/120 (8%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIA-----LAYVTMGIDLG-N 223
E F G+++ E +K+ G P Y ++N D VI + + + +
Sbjct: 526 EFTFLGLFSSEMFLKMYGCG----PRLYFHSSFNCFDCGVIIGSIFDVVWTIIRPETSFG 581
Query: 224 LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
++ LR R+LR K L+ +V +++ S+K++ ++ L + VFAL+G+Q++ G
Sbjct: 582 ISVLRALRLLRIFKITKYWASLRNLVVSLMSSMKSIISLLFLLFLFIVVFALLGMQLFGG 641
>UniRef50_Q13698 Cluster: Voltage-dependent L-type calcium channel
subunit alpha-1S; n=36; Euteleostomi|Rep:
Voltage-dependent L-type calcium channel subunit alpha-1S
- Homo sapiens (Human)
Length = 1873
Score = 308 bits (757), Expect = 8e-82
Identities = 209/682 (30%), Positives = 360/682 (52%), Gaps = 55/682 (8%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+R+ +++ T+F ++ ILLSS ALA ED + + IL + D FT +F +E
Sbjct: 788 IRVLCHRIVNATWFTNFILLFILLSSAALAAEDP-IRADSMRNQILKHFDIGFTSVFTVE 846
Query: 1267 MLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALR 1322
+++K G + N + LD ++V VSLI+ + I K +R LR LR
Sbjct: 847 IVLKMTTYGAFLHKGSFCRNYFNMLDLLVVAVSLISMGLE---SSAISVVKILRVLRVLR 903
Query: 1323 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHT 1382
PLRA++R +G++ VV + AI +I N++LV + +FA +GVQLF GK+F+C D++
Sbjct: 904 PLRAINRAKGLKHVVQCMFVAISTIGNIVLVTTLLQFMFACIGVQLFKGKFFRCTDLSKM 963
Query: 1383 TLS-----HEIIPDKNACTLE--NYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDA 1435
T + + D + +E + W +S +FD+V A + LF V+TF+GW Q++ A
Sbjct: 964 TEEECRGYYYVYKDGDPMQIELRHREWVHSDFHFDNVLSAMMSLFTVSTFEGWPQLLYKA 1023
Query: 1436 IDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFM 1495
IDS PI + M ++ +N+F+G +I F EQ + + E+
Sbjct: 1024 IDSNAEDVGPIYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDK 1083
Query: 1496 TEDQKKYYNAMKKMGSKKPLKA-IPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMT 1554
+ Q Y A+K +PL+ IP+ ++ Q V+ IVT F+ ++ I LN + +
Sbjct: 1084 NQRQCVQY-ALK----ARPLRCYIPKNPYQYQ--VWYIVTSSYFEYLMFALIMLNTICLG 1136
Query: 1555 LDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILS 1613
+ HY QSE + + D LN+ F +IF+ E +LK+ A + YF +PWN+FDF++V+ SI+
Sbjct: 1137 MQHYNQSEQMNHISDILNVAFTIIFTLEMILKLMAFKARGYFGDPWNVFDFLIVIGSIID 1196
Query: 1614 LVLSDIIEKYFVSPTLL----------------RV----VRVAKVGRVLRLVKGAKGIRT 1653
++LS+ I+ + S L R+ R+ +V R+++L+ A+G+RT
Sbjct: 1197 VILSE-IDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRT 1255
Query: 1654 LLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF--MHVKDKGGLDDVYNFKTFVQSMIL 1711
LL+ S AL + LL+ ++ FI+A+ GM F + + D ++ NF+TF Q+++L
Sbjct: 1256 LLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLL 1315
Query: 1712 LFQMSTSAGWDGVLDGIINEEECD-LPDNERGSPGNCGSATIGITYLLSYLVISFLIVIN 1770
LF+ +T W +L + CD D G CG+ Y +S+ ++ +VIN
Sbjct: 1316 LFRCATGEAWQEILLACSYGKLCDPESDYAPGEEYTCGT-NFAYYYFISFYMLCAFLVIN 1374
Query: 1771 MYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPL 1830
+++AVI++N+ T D L D + IW +DP+ I++ + L ++PPL
Sbjct: 1375 LFVAVIMDNFDYLTRD-WSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPL 1433
Query: 1831 QIHK--PNKY---KIISMDIPI 1847
K P++ +++ M++P+
Sbjct: 1434 GFGKFCPHRVACKRLVGMNMPL 1455
Score = 123 bits (296), Expect = 6e-26
Identities = 93/328 (28%), Positives = 160/328 (48%), Gaps = 58/328 (17%)
Query: 116 SATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMI----MPTTPT------ 165
S AL+ L NP+R+ I I+ F I+ TI NC+ + MP
Sbjct: 26 SPPRALFCLTLENPLRKACISIVEWKPFETIILLTIFANCVALAVYLPMPEDDNNSLNLG 85
Query: 166 VESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN-- 223
+E E F +++ E+A+K++A GF+ YLR WN LDF ++ L T+ ++ N
Sbjct: 86 LEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFTIVFLGVFTVILEQVNVI 145
Query: 224 ---------------LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMF 268
+ ALR FRVLR L+ V+ VP L+ ++ ++ +++ L + +L +F
Sbjct: 146 QSHTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLF 205
Query: 269 SLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCG 328
+ ++A++GL+++ G + + C + G+ T EN E P
Sbjct: 206 MVIIYAIIGLELFKGKMHKTCYFI----GTDIVATVENEE--------------PSPCAR 247
Query: 329 NSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWEN-LY------- 380
SG G C G+ P PN+G T FD FG++ L+ ++ +T + W + LY
Sbjct: 248 TGSGRRCTINGSECRGGW-PGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYWVNDAIG 306
Query: 381 ----QLFFVVIIFLGSFYLVNLILAIVA 404
++FV +I LGSF+++NL+L +++
Sbjct: 307 NEWPWIYFVTLILLGSFFILNLVLGVLS 334
Score = 100 bits (239), Expect = 5e-19
Identities = 69/256 (26%), Positives = 133/256 (51%), Gaps = 18/256 (7%)
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL 1590
+IV K F +++L + LN L++ +H+ Q + + D N + + +F++E L+K++ L
Sbjct: 427 DIVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTRLQDIANRVLLSLFTTEMLMKMYGL 486
Query: 1591 RY-HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
YF+ +N FD VV IL ++L +E ++P + V+R ++ R+ ++ K
Sbjct: 487 GLRQYFMSIFNRFDCFVVCSGILEILL---VESGAMTPLGISVLRCIRLLRIFKITKYWT 543
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLD-DVYNFKTFVQS 1708
+ L+ +L S+ ++ ++ LLLFL + IFA+ GM F D + NF F Q+
Sbjct: 544 SLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQA 603
Query: 1709 MILLFQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLI 1767
+I +FQ+ T W ++ +GI+ G P G + Y + V I
Sbjct: 604 LISVFQVLTGEDWTSMMYNGIM----------AYGGPSYPG--MLVCIYFIILFVCGNYI 651
Query: 1768 VINMYIAVILENYSQA 1783
++N+++A+ ++N ++A
Sbjct: 652 LLNVFLAIAVDNLAEA 667
Score = 92.7 bits (220), Expect = 9e-17
Identities = 87/320 (27%), Positives = 145/320 (45%), Gaps = 54/320 (16%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLP----HRPILQDILYYMDRIFTVI 1262
LR ++E FET ++ I + +ALA V+LP L L ++ F ++
Sbjct: 40 LRKACISIVEWKPFETIILLTIFANCVALA---VYLPMPEDDNNSLNLGLEKLEYFFLIV 96
Query: 1263 FFIEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFV-----------AALCGAG 1307
F IE +K +A GF Y + W LDF IV + + + A + G
Sbjct: 97 FSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFTIVFLGVFTVILEQVNVIQSHTAPMSSKG 156
Query: 1308 GIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQ 1367
K +R R LRPLR +S + ++VV+N++ +A+ +F++ L+ L +I+AI+G++
Sbjct: 157 AGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLE 216
Query: 1368 LFAGK-----YFKCVDMNHTTLSHEIIP-----DKNACTLENYT----W---ENSPMNFD 1410
LF GK YF D+ T + E P CT+ W + +FD
Sbjct: 217 LFKGKMHKTCYFIGTDIVATVENEEPSPCARTGSGRRCTINGSECRGGWPGPNHGITHFD 276
Query: 1411 HVGKAYLCLFQVATFKGWIQIM---NDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXX 1467
+ G + L ++Q T +GW ++ NDAI N + ++Y
Sbjct: 277 NFGFSMLTVYQCITMEGWTDVLYWVNDAIG------------NEWPWIYFVTLILLGSFF 324
Query: 1468 TLNLFIGVIIDNFNEQKKKA 1487
LNL +GV+ F ++++KA
Sbjct: 325 ILNLVLGVLSGEFTKEREKA 344
Score = 87.4 bits (207), Expect = 3e-15
Identities = 75/303 (24%), Positives = 138/303 (45%), Gaps = 35/303 (11%)
Query: 1201 WQGWGTL-RLKTFKLIENTYFETAVITMILLSSLALALEDVHLP-HRPILQDILYYMDRI 1258
W+ W + R K ++++ F VI ++ L++L++A E + P LQDI +R+
Sbjct: 414 WRQWNRIFRWKCHDIVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTRLQDIA---NRV 470
Query: 1259 FTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTL 1318
+F EML+K LG ++YF + + D +V ++ + GA +R +
Sbjct: 471 LLSLFTTEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCI 530
Query: 1319 RALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD 1378
R LR + + +V +L+ +I SI ++LL+ +F +IFA++G+QLF G+Y D
Sbjct: 531 RLLRIFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRY----D 586
Query: 1379 MNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDS 1438
T + NFD+ +A + +FQV T + W +M + I +
Sbjct: 587 FEDTEVRRS--------------------NFDNFPQALISVFQVLTGEDWTSMMYNGIMA 626
Query: 1439 REVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTED 1498
P + + +Y LN+F+ + +DN E + S + E+
Sbjct: 627 YGGPSYP----GMLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLT--SAQKAKAEE 680
Query: 1499 QKK 1501
+K+
Sbjct: 681 KKR 683
Score = 73.3 bits (172), Expect = 6e-11
Identities = 44/176 (25%), Positives = 92/176 (52%), Gaps = 11/176 (6%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVEST--------E 170
++ +I P N IR + I+ F+ FI+ IL++ + +S +
Sbjct: 777 SSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILKHFD 836
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA---L 227
+ FT ++T E +K+ G L ++ R+ +N LD +V+A++ ++MG++ ++ L
Sbjct: 837 IGFTSVFTVEIVLKMTTYGAFLHKGSFCRNYFNMLDLLVVAVSLISMGLESSAISVVKIL 896
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
R RVLR L+ + GLK +V + ++ + +++++T +FA +G+Q++ G
Sbjct: 897 RVLRVLRPLRAINRAKGLKHVVQCMFVAISTIGNIVLVTTLLQFMFACIGVQLFKG 952
Score = 67.3 bits (157), Expect = 4e-09
Identities = 46/172 (26%), Positives = 87/172 (50%), Gaps = 16/172 (9%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLD---HYQQSETFSAVLDYLNMIFIVIFSSECLLKIF 1588
IV K F+ II+L I N + + + + + + L+ L F+++FS E +KI
Sbjct: 47 IVEWKPFETIILLTIFANCVALAVYLPMPEDDNNSLNLGLEKLEYFFLIVFSIEAAMKII 106
Query: 1589 A--LRYH---YFVEPWNLFDFVVVMFSILSLVLSDI-IEKYFVSPTL-------LRVVRV 1635
A +H Y WN+ DF +V + +++L + + + +P ++ +R
Sbjct: 107 AYGFLFHQDAYLRSGWNVLDFTIVFLGVFTVILEQVNVIQSHTAPMSSKGAGLDVKALRA 166
Query: 1636 AKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+V R LRLV G ++ +L ++ ++ LF+I LL+ ++ I+AI G+ F
Sbjct: 167 FRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELF 218
Score = 66.9 bits (156), Expect = 5e-09
Identities = 35/95 (36%), Positives = 59/95 (62%), Gaps = 6/95 (6%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LR+FK+ K W +L+ L++ + ++ ++ +L +L + I IFA++GMQLFG Y F
Sbjct: 533 LRIFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRY-----DF 587
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWD 926
D ++ R NF +F + + VF+VL GE W M++
Sbjct: 588 EDTEVRRSNFDNFPQALISVFQVLTGEDWTSMMYN 622
Score = 57.2 bits (132), Expect = 4e-06
Identities = 43/173 (24%), Positives = 92/173 (53%), Gaps = 12/173 (6%)
Query: 1521 PRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETF-SAVLDYLNMIFIVIF 1579
P + + + IV F I+LFI L+ + + ++++ + +L + ++ F +F
Sbjct: 784 PTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILKHFDIGFTSVF 843
Query: 1580 SSECLLKI-----FALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVR 1634
+ E +LK+ F + + +N+ D +VV S++S+ L E +S +++++R
Sbjct: 844 TVEIVLKMTTYGAFLHKGSFCRNYFNMLDLLVVAVSLISMGL----ESSAIS--VVKILR 897
Query: 1635 VAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
V +V R LR + AKG++ ++ + +++ + NI L+ L+ F+FA G+ F
Sbjct: 898 VLRVLRPLRAINRAKGLKHVVQCMFVAISTIGNIVLVTTLLQFMFACIGVQLF 950
Score = 44.0 bits (99), Expect = 0.042
Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 10/111 (9%)
Query: 224 LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
++ LR R+LR K L +V +++ S++++ +++L + +FAL+G+Q++ G
Sbjct: 524 ISVLRCIRLLRIFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGG 583
Query: 284 VLTQKCVKV-------FPED--GSWGNLTDENWERFCQNETNWYGEGGDYP 325
+ +V FP+ + LT E+W N YG G YP
Sbjct: 584 RYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWTSMMYNGIMAYG-GPSYP 633
Score = 40.7 bits (91), Expect = 0.40
Identities = 32/116 (27%), Positives = 55/116 (47%), Gaps = 10/116 (8%)
Query: 818 NMDKDMDKALKSGNY-----LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFI 872
N+D D + S + +R+ KL + L+ ++ AL + ++ ++ FI
Sbjct: 1221 NVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSFQALPYVALLIVMLFFI 1280
Query: 873 FAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDC 927
+AV+GMQ+FGK + VD NF F + +++FR GE W E + C
Sbjct: 1281 YAVIGMQMFGK--IALVDGTQIN--RNNNFQTFPQAVLLLFRCATGEAWQEILLAC 1332
Score = 36.7 bits (81), Expect = 6.4
Identities = 15/57 (26%), Positives = 36/57 (63%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
KAL++ LR +L P+L ++++ + + M L ++ ++ ++ I+A++G++LF
Sbjct: 162 KALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELF 218
>UniRef50_Q7Z003 Cluster: T-type calcium channel alpha1 subunit
isoform B; n=5; Caenorhabditis elegans|Rep: T-type
calcium channel alpha1 subunit isoform B - Caenorhabditis
elegans
Length = 1885
Score = 308 bits (756), Expect = 1e-81
Identities = 186/611 (30%), Positives = 324/611 (53%), Gaps = 38/611 (6%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
LR+K + + +F+ V+ I ++ + LA+E +P + L+ IFTVIF E
Sbjct: 1148 LRIKCLQTTQKKWFDYTVLFFIGINCITLAMERPSIPPDSFERQFLHISGYIFTVIFTGE 1207
Query: 1267 MLIKWLA----LGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGG----IQAFKTMRTL 1318
M++K +A +G YF + W LD I+V++SLIN L G + +R L
Sbjct: 1208 MMMKVIANGCFIGQAAYFKDGWNILDGILVVISLINIAFELLATGDSPKIFGVIRVLRLL 1267
Query: 1319 RALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCV- 1377
RALRPLR ++R G+++VV L+ ++ I N++L+C F++IF I+GVQLF G + C+
Sbjct: 1268 RALRPLRVINRAPGVKLVVMTLISSLKPIGNIVLICCTFFIIFGILGVQLFKGMMYHCIG 1327
Query: 1378 -DMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAI 1436
++ + T + I D W N NFD++G+A + LF +++ GW+ IM I
Sbjct: 1328 PEVGNVTTKADCIED------YRNKWVNHRYNFDNLGQALMSLFVLSSKDGWVSIMYQGI 1381
Query: 1437 DSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMT 1496
D+ V QPI N + +Y LN+F+GV+++NF+ K K EM
Sbjct: 1382 DAVGVDVQPIENYNEWRMIYFISFLLLVGFFVLNMFVGVVVENFH--KCKEALEKEMREK 1439
Query: 1497 EDQKKYYNAMKK------MGSKKPLKAIPRPRW----RPQAIVFEIVTDKKFDMIIMLFI 1546
E +K+ +K+ M K+ P + + + IVT K FD+ I I
Sbjct: 1440 EKEKRLKRKLKRQKFEESMAGKRKKMERNYPYYHDYGHTRLFLHGIVTSKYFDLAIAAVI 1499
Query: 1547 GLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFV 1605
G+N+++M ++ Y VL LN F +F+ E +K+ AL + +F+E WN D
Sbjct: 1500 GINVISMAMEFYMMPMGLKYVLKALNYFFTAVFTLEAAMKLIALGFKRFFIEKWNRLDMF 1559
Query: 1606 VVMFSILSLVLSDI-IEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPA 1664
+V+ SI ++ + + ++PT++RV+RV ++ RVL+L+K AKGIR+LL + +LP
Sbjct: 1560 IVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVLKLLKMAKGIRSLLDTVGEALPQ 1619
Query: 1665 LFNICLLLFLVMFIFAIFGMSFFMHVKDK-----GGLDDVYNFKTFVQSMILLFQMSTSA 1719
+ N+ L FL+ FIFA G+ F ++ GL + +FK F + + LF+++T
Sbjct: 1620 VGNLGSLFFLLFFIFAALGVELFGKLECSEDHPCDGLGEHAHFKNFGMAFLTLFRIATGD 1679
Query: 1720 GWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILEN 1779
W+G++ + ++CD D+ C + + + +++IS +++N+ +AV++++
Sbjct: 1680 NWNGIMKDAL-RDDCDSSDH--CETNCCVDPILAPCFFVIFVLISQFVLVNVVVAVLMKH 1736
Query: 1780 YSQATEDVQEG 1790
++ + EG
Sbjct: 1737 LEESNKRDAEG 1747
Score = 99 bits (238), Expect = 6e-19
Identities = 55/124 (44%), Positives = 75/124 (60%), Gaps = 4/124 (3%)
Query: 1251 ILYYMDRIFTVIFFIEMLIKWLALGFQ---KYFTNAWCWLDFIIVMVSLINFVAALCGAG 1307
IL +D V F EM+IK +ALGF Y ++ W LDF IVM + FV G
Sbjct: 166 ILDIIDNCIFVYFAFEMVIKIMALGFYGPAAYMSDTWNRLDFFIVMAGIAEFVLHEYLGG 225
Query: 1308 GIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQ 1367
I +RT+R LRPLRA++R+ MR++VN L+ +P + NVLL+C + IF I+GVQ
Sbjct: 226 NIN-LTAIRTVRVLRPLRAVNRIPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIVGVQ 284
Query: 1368 LFAG 1371
L+AG
Sbjct: 285 LWAG 288
Score = 94.3 bits (224), Expect = 3e-17
Identities = 67/242 (27%), Positives = 125/242 (51%), Gaps = 26/242 (10%)
Query: 1199 PFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRI 1258
P++ +G RL ++ + YF+ A+ +I ++ +++A+E +P L+ +L ++
Sbjct: 1470 PYYHDYGHTRLFLHGIVTSKYFDLAIAAVIGINVISMAMEFYMMPMG--LKYVLKALNYF 1527
Query: 1259 FTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFV----AALCGAGGIQAFKT 1314
FT +F +E +K +ALGF+++F W LD IV++S+ + AL +
Sbjct: 1528 FTAVFTLEAAMKLIALGFKRFFIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRV 1587
Query: 1315 MRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYF 1374
MR LR R L+ + +G+R +++ + +A+P + N+ + + + IFA +GV+LF GK
Sbjct: 1588 MRVLRIARVLKLLKMAKGIRSLLDTVGEALPQVGNLGSLFFLLFFIFAALGVELF-GK-L 1645
Query: 1375 KCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMND 1434
+C + D L + +F + G A+L LF++AT W IM D
Sbjct: 1646 ECSE------------DHPCDGLGEHA------HFKNFGMAFLTLFRIATGDNWNGIMKD 1687
Query: 1435 AI 1436
A+
Sbjct: 1688 AL 1689
Score = 91.5 bits (217), Expect = 2e-16
Identities = 56/184 (30%), Positives = 100/184 (54%), Gaps = 18/184 (9%)
Query: 129 PIRRVAIYILVHPLFSLFIITTILVNCILMIM-------PTTPTV--ESTEVIFTGIYT- 178
P R+ A+ +++ P F + I++NC+ + M P T + ++I I+
Sbjct: 118 PPRKWALQMVMSPWFDRITMAVIMINCVTLGMYRPCEDGPDCDTYRCQILDIIDNCIFVY 177
Query: 179 --FESAVKVMARGFILQPFTYLRDAWNWLDFVVI--ALAYVTMGIDLG---NLAALRTFR 231
FE +K+MA GF P Y+ D WN LDF ++ +A + LG NL A+RT R
Sbjct: 178 FAFEMVIKIMALGFY-GPAAYMSDTWNRLDFFIVMAGIAEFVLHEYLGGNINLTAIRTVR 236
Query: 232 VLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVK 291
VLR L+ V +P ++ +V +++++ L +V++L F +F ++G+Q++ G+L +CV
Sbjct: 237 VLRPLRAVNRIPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCVI 296
Query: 292 VFPE 295
P+
Sbjct: 297 NLPK 300
Score = 88.2 bits (209), Expect = 2e-15
Identities = 72/294 (24%), Positives = 144/294 (48%), Gaps = 41/294 (13%)
Query: 1534 TDKK-FDMIIMLFIGLNMLTMTLDHYQ-QSETFSAVLDYLN-MIFIVIFSSECLLKIFAL 1590
T KK FD ++ FIG+N +T+ ++ ++F +++ IF VIF+ E ++K+ A
Sbjct: 1156 TQKKWFDYTVLFFIGINCITLAMERPSIPPDSFERQFLHISGYIFTVIFTGEMMMKVIAN 1215
Query: 1591 -----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTL---LRVVRVAKVGRVL 1642
+ YF + WN+ D ++V+ S++++ + SP + +RV+R+ + R L
Sbjct: 1216 GCFIGQAAYFKDGWNILDGILVVISLINIAFELLATGD--SPKIFGVIRVLRLLRALRPL 1273
Query: 1643 RLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM------------HV 1690
R++ A G++ ++ L SL + NI L+ IF I G+ F +V
Sbjct: 1274 RVINRAPGVKLVVMTLISSLKPIGNIVLICCTFFIIFGILGVQLFKGMMYHCIGPEVGNV 1333
Query: 1691 KDKGG-LDDV--------YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNER 1741
K ++D YNF Q+++ LF +S+ GW ++ I+ D+ E
Sbjct: 1334 TTKADCIEDYRNKWVNHRYNFDNLGQALMSLFVLSSKDGWVSIMYQGIDAVGVDVQPIEN 1393
Query: 1742 GSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDD 1795
+ + Y +S+L++ V+NM++ V++EN+ + E +++ + + +
Sbjct: 1394 YNEWR-------MIYFISFLLLVGFFVLNMFVGVVVENFHKCKEALEKEMREKE 1440
Score = 84.6 bits (200), Expect = 2e-14
Identities = 53/205 (25%), Positives = 100/205 (48%), Gaps = 19/205 (9%)
Query: 100 QTTFVVISKGKDIFRFSATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMI 159
Q TFV K +L+++ P NP+R + F ++ I +NCI +
Sbjct: 1118 QNTFVRKLLKKTCLHNRTEFSLFLMGPKNPLRIKCLQTTQKKWFDYTVLFFIGINCITLA 1177
Query: 160 M--PTTPT-------VESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVI 210
M P+ P + + IFT I+T E +KV+A G + Y +D WN LD +++
Sbjct: 1178 MERPSIPPDSFERQFLHISGYIFTVIFTGEMMMKVIANGCFIGQAAYFKDGWNILDGILV 1237
Query: 211 ALAYVTMGIDL----------GNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLR 260
++ + + +L G + LR R LR L+ + PG+K +V +I S+K +
Sbjct: 1238 VISLINIAFELLATGDSPKIFGVIRVLRLLRALRPLRVINRAPGVKLVVMTLISSLKPIG 1297
Query: 261 DVIILTMFSLSVFALMGLQIYMGVL 285
+++++ +F ++G+Q++ G++
Sbjct: 1298 NIVLICCTFFIIFGILGVQLFKGMM 1322
Score = 77.4 bits (182), Expect = 4e-12
Identities = 53/179 (29%), Positives = 92/179 (51%), Gaps = 9/179 (5%)
Query: 1510 GSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLD 1569
G + K+ P W + + + V F I++ I +N L+M ++++QQ E + +L+
Sbjct: 627 GEEAKKKSTPSKLWWFREKIQKFVICDHFTRGILVAILVNTLSMGVEYHQQPEILTVILE 686
Query: 1570 YLNMIFIVIFSSECLLKIFAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPT 1628
Y N+ F +F+ E LLKI A + Y + +NLFD +V S+L L +
Sbjct: 687 YSNLFFTALFALEMLLKIIASGLFGYLADGFNLFDGGIVALSVLEL--------FQEGKG 738
Query: 1629 LLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
L V+R ++ R+L+LV+ +R L + ++ + LL L +FIF+I GM+ F
Sbjct: 739 GLSVLRTFRLLRILKLVRFMPALRYQLVVMLRTMDNVTVFFGLLVLFIFIFSILGMNLF 797
Score = 75.8 bits (178), Expect = 1e-11
Identities = 54/168 (32%), Positives = 89/168 (52%), Gaps = 7/168 (4%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEM 1267
R K K + +F ++ IL+++L++ +E P IL IL Y + FT +F +EM
Sbjct: 643 REKIQKFVICDHFTRGILVAILVNTLSMGVEYHQQPE--ILTVILEYSNLFFTALFALEM 700
Query: 1268 LIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAM 1327
L+K +A G Y + + D IV +S++ G GG+ +T R LR L+ +R M
Sbjct: 701 LLKIIASGLFGYLADGFNLFDGGIVALSVLELFQE--GKGGLSVLRTFRLLRILKLVRFM 758
Query: 1328 SRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK 1375
++ VV+ + + ++F LLV IF IF+I+G+ LF K+ K
Sbjct: 759 PALRYQLVVMLRTMDNV-TVFFGLLVLFIF--IFSILGMNLFGCKFCK 803
Score = 74.5 bits (175), Expect = 3e-11
Identities = 53/172 (30%), Positives = 82/172 (47%), Gaps = 13/172 (7%)
Query: 1525 PQAIVFEIVTDKKFDMIIMLFIGLNMLTMTL----DHYQQSETFSA-VLDYLNMIFIVIF 1579
P+ ++V FD I M I +N +T+ + + +T+ +LD ++ V F
Sbjct: 119 PRKWALQMVMSPWFDRITMAVIMINCVTLGMYRPCEDGPDCDTYRCQILDIIDNCIFVYF 178
Query: 1580 SSECLLKIFALRYH----YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRV 1635
+ E ++KI AL ++ Y + WN DF +VM I VL + Y L +R
Sbjct: 179 AFEMVIKIMALGFYGPAAYMSDTWNRLDFFIVMAGIAEFVLHE----YLGGNINLTAIRT 234
Query: 1636 AKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+V R LR V +R L+ L +LP L N+ LL F V FIF I G+ +
Sbjct: 235 VRVLRPLRAVNRIPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLW 286
Score = 64.5 bits (150), Expect = 3e-08
Identities = 43/147 (29%), Positives = 80/147 (54%), Gaps = 12/147 (8%)
Query: 143 FSLFIITTILVNCILMIM-----PTTPTV--ESTEVIFTGIYTFESAVKVMARGFILQPF 195
F+ I+ ILVN + M + P TV E + + FT ++ E +K++A G F
Sbjct: 655 FTRGILVAILVNTLSMGVEYHQQPEILTVILEYSNLFFTALFALEMLLKIIASGL----F 710
Query: 196 TYLRDAWNWLDFVVIALAYVTMGID-LGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIE 254
YL D +N D ++AL+ + + + G L+ LRTFR+LR LK V +P L+ + ++
Sbjct: 711 GYLADGFNLFDGGIVALSVLELFQEGKGGLSVLRTFRLLRILKLVRFMPALRYQLVVMLR 770
Query: 255 SVKNLRDVIILTMFSLSVFALMGLQIY 281
++ N+ L + + +F+++G+ ++
Sbjct: 771 TMDNVTVFFGLLVLFIFIFSILGMNLF 797
Score = 51.2 bits (117), Expect = 3e-04
Identities = 34/136 (25%), Positives = 69/136 (50%), Gaps = 6/136 (4%)
Query: 797 VELFITLCIVVNTLFMALDHHNM--DKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGR 854
+++FI + + +F + + + + + ++ RV KL K + L+ +G
Sbjct: 1556 LDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVLKLLKMAKGIRSLLDTVGE 1615
Query: 855 TMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP-DGDLPRWNFTDFMHSFMIVF 913
+ +GNL + ++ FIFA +G++LFGK ++ + P DG +F +F +F+ +F
Sbjct: 1616 ALPQVGNLGSLFFLLFFIFAALGVELFGK--LECSEDHPCDGLGEHAHFKNFGMAFLTLF 1673
Query: 914 RVLCGE-WIESMWDCM 928
R+ G+ W M D +
Sbjct: 1674 RIATGDNWNGIMKDAL 1689
Score = 49.2 bits (112), Expect = 0.001
Identities = 47/181 (25%), Positives = 85/181 (46%), Gaps = 30/181 (16%)
Query: 137 ILVHPLFSLFIITTILVNCILMIMP--TTP-----TVESTEVIFTGIYTFESAVKVMARG 189
I+ F L I I +N I M M P +++ FT ++T E+A+K++A G
Sbjct: 1485 IVTSKYFDLAIAAVIGINVISMAMEFYMMPMGLKYVLKALNYFFTAVFTLEAAMKLIALG 1544
Query: 190 FILQPFTYLRDAWNWLDFVVIALAY----------VTMGIDLGNLAALRTFRVLRALKTV 239
F + + WN LD ++ L+ + + I+ + +R R+ R LK +
Sbjct: 1545 F----KRFFIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVLKLL 1600
Query: 240 AIVPGLKTI---VGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPED 296
+ G++++ VG + V NL + L F +FA +G++++ G L +C + P D
Sbjct: 1601 KMAKGIRSLLDTVGEALPQVGNLGSLFFLLFF---IFAALGVELF-GKL--ECSEDHPCD 1654
Query: 297 G 297
G
Sbjct: 1655 G 1655
Score = 46.0 bits (104), Expect = 0.011
Identities = 23/69 (33%), Positives = 38/69 (55%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L++ LR+ KL + P L + +M RTM + +L + IFIF+++GM LFG +
Sbjct: 743 LRTFRLLRILKLVRFMPALRYQLVVMLRTMDNVTVFFGLLVLFIFIFSILGMNLFGCKFC 802
Query: 887 DYVDRFPDG 895
++F G
Sbjct: 803 KVEEKFLGG 811
Score = 42.3 bits (95), Expect = 0.13
Identities = 19/70 (27%), Positives = 41/70 (58%), Gaps = 11/70 (15%)
Query: 349 NPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVN 397
NP G SFD G+A+++ F +++ + W ++ ++FV++I +G+F+++N
Sbjct: 385 NPFQGSVSFDNIGFAWVAIFLVISLEGWTDIMYYVQDAHSFWNWIYFVLLIVIGAFFMIN 444
Query: 398 LILAIVAMSY 407
L L ++A +
Sbjct: 445 LCLVVIATQF 454
Score = 38.3 bits (85), Expect = 2.1
Identities = 15/56 (26%), Positives = 34/56 (60%)
Query: 826 ALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
A+++ LR + P++ +L++++ T+ LGN+ + + FIF ++G+QL+
Sbjct: 231 AIRTVRVLRPLRAVNRIPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLW 286
>UniRef50_Q4S5H0 Cluster: Chromosome 3 SCAF14730, whole genome shotgun
sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 3
SCAF14730, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 2206
Score = 306 bits (752), Expect = 3e-81
Identities = 169/547 (30%), Positives = 299/547 (54%), Gaps = 26/547 (4%)
Query: 1258 IFTVIFFIEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQA-F 1312
IFT IF EM +K +++G Q Y ++W LD +V VSL++ V ++ G I
Sbjct: 1207 IFTAIFVGEMTLKVVSMGLYMGQQAYLRSSWNVLDGFLVFVSLVDIVVSMAGGAKILGVL 1266
Query: 1313 KTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGK 1372
+ +R LR LRPLR +SR G+++VV L+ ++ I N++L+C F++IF I+GVQLF GK
Sbjct: 1267 RVLRLLRTLRPLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLFKGK 1326
Query: 1373 YFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIM 1432
+F C+ + +++ K+ C NY W + NFD++G+A + LF +A+ GW+ IM
Sbjct: 1327 FFYCLGPDIRNITN-----KSDCLQANYKWVHHKYNFDNLGQALMSLFVLASKDGWVNIM 1381
Query: 1433 NDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLE 1492
+D+ V +QP+ N +M LY LN+F+GV+++NF++ ++
Sbjct: 1382 YHGLDAVGVDQQPVTNNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEVEEA 1441
Query: 1493 MFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLT 1552
E +++ ++ K P A ++++ + T+ D+II I +N++T
Sbjct: 1442 KRREEKRQRRMEKKRRKAQKLPYYA---SYGHVRSMIHTLCTNHYLDLIITFIIAINVIT 1498
Query: 1553 MTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFVVVMFSI 1611
M+L+HY Q + L Y N F F E +LK+ A + +F + WN D +V+ S+
Sbjct: 1499 MSLEHYNQPYSLDLGLKYCNYFFTSTFVLESILKLIAFGFRRFFKDRWNQLDLAIVLLSV 1558
Query: 1612 LSLVLSDI-IEKYF-VSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNIC 1669
+ + L +I I ++PT++R++RV ++ RVL+L+K A G+R LL + +LP + N+
Sbjct: 1559 MGITLEEIEISAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLG 1618
Query: 1670 LLLFLVMFIFAIFGMSFFMHVKDKG-----GLDDVYNFKTFVQSMILLFQMSTSAGWDGV 1724
LL L+ FI+A G+ F + G+ F+ F + + LFQ+ST W+G+
Sbjct: 1619 LLFMLLFFIYAALGVELFGELVCNADYPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGI 1678
Query: 1725 LDGIINEEECDLPDNERGSPGNCGSAT--IGITYLLSYLVISFLIVINMYIAVILENYSQ 1782
+ + EC PD+ NC + I Y +S+++ + ++IN+ +AV++++
Sbjct: 1679 MKDTL--RECP-PDHNTDVDYNCNPSLQFISPMYFVSFVLTAQFVLINVVVAVLMKHLDD 1735
Query: 1783 ATEDVQE 1789
+ ++ QE
Sbjct: 1736 SNKEAQE 1742
Score = 103 bits (248), Expect = 4e-20
Identities = 72/271 (26%), Positives = 140/271 (51%), Gaps = 34/271 (12%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR 1591
IV K F IM+ I +N ++M ++H+ Q + + VL+ N++F +F+ E +LK+ A
Sbjct: 588 IVESKYFSRGIMIAILINTISMGIEHHNQPDELTNVLEICNIVFTSMFTLEMILKLSAFG 647
Query: 1592 -YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
+ Y P+N+FD ++V+ S+ ++ + L V+R ++ RV++LV+
Sbjct: 648 FFEYLRNPYNIFDGIIVIISVCEIIGQ--------ADGGLSVLRTFRLLRVIKLVRFMPA 699
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF---MHVKDKGG--LDDVYNFKTF 1705
+R L L ++ + C+LL L +FIF+I GM F +K + G + D NF +
Sbjct: 700 LRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLKTEAGDTVPDRKNFDSL 759
Query: 1706 VQSMILLFQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVIS 1764
+ +++ +FQ+ T W+ VL +G+++ C A++ Y ++ +
Sbjct: 760 LWAIVTVFQILTQEDWNVVLYNGMVSTSPC---------------ASL---YFVALMTFG 801
Query: 1765 FLIVINMYIAVILENYSQATEDVQEGLTDDD 1795
++ N+ +A+++E + QA D +DDD
Sbjct: 802 NYVLFNLLVAILVEGF-QAEGDANRSYSDDD 831
Score = 97.1 bits (231), Expect = 4e-18
Identities = 77/306 (25%), Positives = 140/306 (45%), Gaps = 33/306 (10%)
Query: 1199 PFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRI 1258
P++ +G +R L N Y + + +I ++ + ++LE + P+ L L Y +
Sbjct: 1463 PYYASYGHVRSMIHTLCTNHYLDLIITFIIAINVITMSLEHYNQPYSLDLG--LKYCNYF 1520
Query: 1259 FTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFV---AALCGAGGIQ--AFK 1313
FT F +E ++K +A GF+++F + W LD IV++S++ + A I +
Sbjct: 1521 FTSTFVLESILKLIAFGFRRFFKDRWNQLDLAIVLLSVMGITLEEIEISAALPINPTIIR 1580
Query: 1314 TMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
MR LR R L+ + GMR +++ +VQA+P + N+ L+ ++ + I+A +GV+LF G+
Sbjct: 1581 IMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELF-GEL 1639
Query: 1374 FKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMN 1433
D +S T EN+ G A+L LFQV+T W IM
Sbjct: 1640 VCNADYPCEGMSRH-------ATFENF------------GMAFLTLFQVSTGDNWNGIMK 1680
Query: 1434 DAI------DSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKA 1487
D + + +V +Y +N+ + V++ + ++ K+A
Sbjct: 1681 DTLRECPPDHNTDVDYNCNPSLQFISPMYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEA 1740
Query: 1488 GGSLEM 1493
EM
Sbjct: 1741 QEEAEM 1746
Score = 87.8 bits (208), Expect = 3e-15
Identities = 58/235 (24%), Positives = 122/235 (51%), Gaps = 27/235 (11%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W +R K + ++E+ YF ++ IL++++++ +E + P L ++L + +FT +F
Sbjct: 578 WTGMRRKLWGIVESKYFSRGIMIAILINTISMGIEHHNQPDE--LTNVLEICNIVFTSMF 635
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRP 1323
+EM++K A GF +Y N + D IIV++S+ + GG+ +T R LR ++
Sbjct: 636 TLEMILKLSAFGFFEYLRNPYNIFDGIIVIISVCEIIGQ--ADGGLSVLRTFRLLRVIKL 693
Query: 1324 LRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTT 1383
+R M ++ VV L++ + ++ ++ ++F IF+I+G+ +F K+ + T
Sbjct: 694 VRFMPALRRQLVV---LMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKF------SLKT 744
Query: 1384 LSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDS 1438
+ + +PD+ NFD + A + +FQ+ T + W ++ + + S
Sbjct: 745 EAGDTVPDRK--------------NFDSLLWAIVTVFQILTQEDWNVVLYNGMVS 785
Score = 75.4 bits (177), Expect = 2e-11
Identities = 48/165 (29%), Positives = 89/165 (53%), Gaps = 12/165 (7%)
Query: 125 DPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMP-------TTPTVESTEVIFTGIY 177
D + +RR I+ FS I+ IL+N I M + T +E ++FT ++
Sbjct: 576 DAWTGMRRKLWGIVESKYFSRGIMIAILINTISMGIEHHNQPDELTNVLEICNIVFTSMF 635
Query: 178 TFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM-GIDLGNLAALRTFRVLRAL 236
T E +K+ A GF F YLR+ +N D +++ ++ + G G L+ LRTFR+LR +
Sbjct: 636 TLEMILKLSAFGF----FEYLRNPYNIFDGIIVIISVCEIIGQADGGLSVLRTFRLLRVI 691
Query: 237 KTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
K V +P L+ + +++++ N+ +L M + +F+++G+ I+
Sbjct: 692 KLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIF 736
Score = 72.5 bits (170), Expect = 1e-10
Identities = 37/119 (31%), Positives = 67/119 (56%), Gaps = 7/119 (5%)
Query: 172 IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID-------LGNL 224
IFT I+ E +KV++ G + YLR +WN LD ++ ++ V + + LG L
Sbjct: 1207 IFTAIFVGEMTLKVVSMGLYMGQQAYLRSSWNVLDGFLVFVSLVDIVVSMAGGAKILGVL 1266
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
LR R LR L+ ++ PGLK +V +I S+K + +++++ +F ++G+Q++ G
Sbjct: 1267 RVLRLLRTLRPLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLFKG 1325
Score = 51.6 bits (118), Expect = 2e-04
Identities = 35/119 (29%), Positives = 60/119 (50%), Gaps = 9/119 (7%)
Query: 1217 NTYFETAVITMILLSSLALALEDV--HLPHRPILQDILYYMDRIFTVIFFIEMLIKWLAL 1274
+T+FE I +ILL+ + L + ++ +L D + F +EM++K +AL
Sbjct: 66 STWFERISIMVILLNCVTLGMYQPCENIDCASDHCQVLQAFDAFIYIFFALEMVVKMVAL 125
Query: 1275 GF---QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRM 1330
G + Y + W LDF IVM ++ + L +RT+R LRPL+A++R+
Sbjct: 126 GIFGRRCYLGDTWNRLDFFIVMAGMVEYSLDLQNIN----LSAIRTVRVLRPLKAINRV 180
Score = 51.6 bits (118), Expect = 2e-04
Identities = 30/69 (43%), Positives = 39/69 (56%), Gaps = 3/69 (4%)
Query: 177 YTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLG--NLAALRTFRVLR 234
+ E VK++A G I YL D WN LDF ++ V +DL NL+A+RT RVLR
Sbjct: 114 FALEMVVKMVALG-IFGRRCYLGDTWNRLDFFIVMAGMVEYSLDLQNINLSAIRTVRVLR 172
Query: 235 ALKTVAIVP 243
LK + VP
Sbjct: 173 PLKAINRVP 181
Score = 51.6 bits (118), Expect = 2e-04
Identities = 33/119 (27%), Positives = 60/119 (50%), Gaps = 8/119 (6%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY- 885
L++ LRV KL + P L + ++ +TM + +L + IFIF+++GM +FG +
Sbjct: 682 LRTFRLLRVIKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFS 741
Query: 886 --VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSCIPFFLA 941
+ D PD R NF + + + VF++L E W +++ M+ +F+A
Sbjct: 742 LKTEAGDTVPD----RKNFDSLLWAIVTVFQILTQEDWNVVLYNGMVSTSPCASLYFVA 796
Score = 44.0 bits (99), Expect = 0.042
Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 2/96 (2%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
RV KL K + L+ + + + +GNL + ++ FI+A +G++LFG+ V D
Sbjct: 1589 RVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGE-LVCNADYPC 1647
Query: 894 DGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
+G F +F +F+ +F+V G+ W M D +
Sbjct: 1648 EGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTL 1683
Score = 43.6 bits (98), Expect = 0.056
Identities = 21/70 (30%), Positives = 42/70 (60%), Gaps = 11/70 (15%)
Query: 349 NPNYGYTSFDTFGWAFLSAFRLMTQDYW-ENLYQ----------LFFVVIIFLGSFYLVN 397
NP+ G SFD +A++ F+++T + W E +Y ++F+++I +GSF+++N
Sbjct: 330 NPHKGAISFDNIVYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFILLIIIGSFFMIN 389
Query: 398 LILAIVAMSY 407
L L ++A +
Sbjct: 390 LCLVVIATQF 399
Score = 39.5 bits (88), Expect = 0.91
Identities = 21/80 (26%), Positives = 41/80 (51%), Gaps = 10/80 (12%)
Query: 1407 MNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXX 1466
++FD++ A++ +FQV T +GW++IM +D+ + Y ++Y
Sbjct: 336 ISFDNIVYAWIVIFQVITLEGWVEIMYYVMDAH----------SFYNFIYFILLIIIGSF 385
Query: 1467 XTLNLFIGVIIDNFNEQKKK 1486
+NL + VI F+E K++
Sbjct: 386 FMINLCLVVIATQFSETKQR 405
Score = 36.7 bits (81), Expect = 6.4
Identities = 14/49 (28%), Positives = 27/49 (55%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
LR ++ P L L++ + ++ +GN+ + C IF ++G+QLF
Sbjct: 1275 LRPLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLF 1323
>UniRef50_Q8JFR0 Cluster: Voltage-gated calcium channel subunit
Cav1.3; n=4; Euteleostomi|Rep: Voltage-gated calcium
channel subunit Cav1.3 - Oncorhynchus mykiss (Rainbow
trout) (Salmo gairdneri)
Length = 2155
Score = 306 bits (751), Expect = 4e-81
Identities = 215/702 (30%), Positives = 365/702 (51%), Gaps = 67/702 (9%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+R+ KLI + F ++ I+LSS++LA ED + + +L Y D +FT +F E
Sbjct: 852 IRVGCHKLINHHIFTNLILVFIMLSSVSLAAEDP-IRNFSARNIVLGYADYVFTSMFTFE 910
Query: 1267 MLIKWLALG--FQK--YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALR 1322
+++K G K + N + LD ++V VSL++F + I K +R LR LR
Sbjct: 911 IMLKMTTYGAFLHKGAFCRNTFNLLDLLVVGVSLVSFCIQ---SSAISVVKILRVLRVLR 967
Query: 1323 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHT 1382
PLRA++R +G++ V+ +V AI +I N+++V + +FA +GVQLF GK+++C D +
Sbjct: 968 PLRAINRAKGLKHVIQCVVGAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKS 1027
Query: 1383 -------TLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDA 1435
T H D N ++ + S NFD+V A + LF V+TF+GW ++ A
Sbjct: 1028 SPDECKGTYIHFKDGDVNQPAIQKRERQKSEFNFDNVLMAMMALFTVSTFEGWPSLLYKA 1087
Query: 1436 IDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFM 1495
IDS PI I + ++ +N+F+G +I NF EQ +K + E+
Sbjct: 1088 IDSNRENLGPIYNYRIEISIFFIIYIIIIAFFMMNIFVGFVIVNFQEQGEKEYKNCELDK 1147
Query: 1496 TEDQKKYYNAMKKMGSKKPLKA-IPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMT 1554
+ Q Y A+K +PL+ IP+ + Q + +V F+ I+ + I LN L +
Sbjct: 1148 NQRQCVEY-ALK----ARPLRRYIPKNPY--QYKFWYVVNSTGFEYIMFVLIMLNTLCLA 1200
Query: 1555 LDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-----------YFVEPWNLFD 1603
+ HY QSETF+ V+D LNM+F +F++E +LK+ A + YF + WN+FD
Sbjct: 1201 VQHYGQSETFNYVMDILNMVFTAVFTAEMVLKLIAFKPRLCVEKKDRDPGYFGDAWNVFD 1260
Query: 1604 FVVVMFSILSLVLSDI-----IEKYFVSPT-----------------LLRVVRVAKVGRV 1641
+VVM SI+ +VLS+I + + PT + R+ +V R+
Sbjct: 1261 ALVVMGSIVDIVLSEIDKLVEMARGPAPPTEAPQLDESGNTEDSARISITFFRLFRVMRL 1320
Query: 1642 LRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVK--DKGGLDDV 1699
++L+ +GIRTLL+ S AL + LL+ ++ FI+A+ GM F V D ++
Sbjct: 1321 VKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGKVAMVDGTHINRN 1380
Query: 1700 YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECD-LPDNERGSPGNCGSATIGITYLL 1758
NF+TF Q+++LLF+ +T W ++ ++ + CD D G CG A+ Y +
Sbjct: 1381 NNFQTFPQAVLLLFRCATGEAWQEIMLACVSGKLCDPESDYNPGEEMTCG-ASFAYIYFI 1439
Query: 1759 SYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQ 1818
S+ ++ ++IN+++AVI++N+ T D L D + IW +DP+ I++
Sbjct: 1440 SFYMLCAFLIINLFVAVIMDNFDYLTRD-WSILGPHHLDEFKRIWSEYDPEAKGRIKHLD 1498
Query: 1819 LSDFLDVLEPPLQIHK--PNKY---KIISMDIPI-CRGDMMF 1854
+ L ++PPL K P++ ++++M++P+ G +MF
Sbjct: 1499 VVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMF 1540
Score = 95.1 bits (226), Expect = 2e-17
Identities = 63/252 (25%), Positives = 129/252 (51%), Gaps = 23/252 (9%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFV 1596
F ++++ + LN LT++ +HY Q + + V D N + + F+ E + K+++L YFV
Sbjct: 546 FYWLVIILVFLNTLTISSEHYMQPDWLTQVQDVANKVLLGCFTCEMMTKMYSLGLQAYFV 605
Query: 1597 EPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLF 1656
+N FD VV I +L +E +SP + V R ++ R+ ++ + + + L+
Sbjct: 606 SLFNRFDCFVVCGGITETIL---VELAIMSPLGISVFRCVRLLRIFKVTRHWQSLSNLVA 662
Query: 1657 ALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVY----NFKTFVQSMILL 1712
+L S+ ++ ++ LLLFL + IF++ GM F K D+ F F Q+++ +
Sbjct: 663 SLLNSMKSIASLLLLLFLFIIIFSLLGMQVF---GGKFNFDETQTKRSTFDNFPQALLTV 719
Query: 1713 FQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINM 1771
FQ+ T W+ V+ DGI+ G P + G + +++ ++ +++++
Sbjct: 720 FQILTGEDWNAVMYDGIM----------AYGGPSSSG-MIVSFYFIILFICGNYILLNVF 768
Query: 1772 YIAVILENYSQA 1783
++A+ ++N A
Sbjct: 769 FLAIAVDNLGDA 780
Score = 81.8 bits (193), Expect = 2e-13
Identities = 57/194 (29%), Positives = 104/194 (53%), Gaps = 34/194 (17%)
Query: 223 NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYM 282
++ ALR FRVLR L+ V+ VP L+ ++ ++I+++ L + +L +F + ++A++GL++++
Sbjct: 238 DVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFI 297
Query: 283 GVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVC 342
G + C FP G + E+ C G G P+ G +C G+
Sbjct: 298 GKMHATC--FFPSTG----MIAEDDPAPCAIS----GHGRQCPINGT-----ECREGW-- 340
Query: 343 LQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWEN-LY-----------QLFFVVIIFL 390
PN G T+FD F +A L+ F+ +T + W + LY ++FV +I L
Sbjct: 341 -----HGPNNGITNFDNFLFAMLTVFQCITMEGWTDVLYWVNDAIGFGTPAIYFVSLIIL 395
Query: 391 GSFYLVNLILAIVA 404
GSF+++NL+L +++
Sbjct: 396 GSFFVLNLVLGVLS 409
Score = 72.9 bits (171), Expect = 8e-11
Identities = 43/176 (24%), Positives = 90/176 (51%), Gaps = 11/176 (6%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILM--------IMPTTPTVESTE 170
+A +I NPIR ++ H +F+ I+ I+++ + + + +
Sbjct: 841 SAFFIFSKTNPIRVGCHKLINHHIFTNLILVFIMLSSVSLAAEDPIRNFSARNIVLGYAD 900
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA---L 227
+FT ++TFE +K+ G L + R+ +N LD +V+ ++ V+ I ++ L
Sbjct: 901 YVFTSMFTFEIMLKMTTYGAFLHKGAFCRNTFNLLDLLVVGVSLVSFCIQSSAISVVKIL 960
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
R RVLR L+ + GLK ++ V+ +++ + +++I+T +FA +G+Q++ G
Sbjct: 961 RVLRVLRPLRAINRAKGLKHVIQCVVGAIRTIGNIMIVTTLLQFMFACIGVQLFKG 1016
Score = 69.3 bits (162), Expect = 1e-09
Identities = 46/177 (25%), Positives = 88/177 (49%), Gaps = 9/177 (5%)
Query: 1201 WQGWGTL-RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIF 1259
W+ W R K +++ F VI ++ L++L ++ E H L + +++
Sbjct: 526 WRRWNRFCRRKCRLAVKSVPFYWLVIILVFLNTLTISSE--HYMQPDWLTQVQDVANKVL 583
Query: 1260 TVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVA---ALCGAGGIQAFKTMR 1316
F EM+ K +LG Q YF + + D +V + + A+ GI F+ +R
Sbjct: 584 LGCFTCEMMTKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELAIMSPLGISVFRCVR 643
Query: 1317 TLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
LR + R Q + +V +L+ ++ SI ++LL+ +F +IF+++G+Q+F GK+
Sbjct: 644 LLRIFKVTR---HWQSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQVFGGKF 697
Score = 67.7 bits (158), Expect = 3e-09
Identities = 54/196 (27%), Positives = 90/196 (45%), Gaps = 24/196 (12%)
Query: 1306 AGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMG 1365
+GG K +R R LRPLR +S + ++VV+N++++A+ + ++ L+ L +I+AI+G
Sbjct: 234 SGGFDV-KALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIG 292
Query: 1366 VQLFAGKYFKCVDMNHTTLSHEIIPDKNA-------CTLENYT----W---ENSPMNFDH 1411
++LF GK T + E P A C + W N NFD+
Sbjct: 293 LELFIGKMHATCFFPSTGMIAEDDPAPCAISGHGRQCPINGTECREGWHGPNNGITNFDN 352
Query: 1412 VGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNL 1471
A L +FQ T +GW ++ D+ G I Y LNL
Sbjct: 353 FLFAMLTVFQCITMEGWTDVLYWVNDAIGFGTPAI---------YFVSLIILGSFFVLNL 403
Query: 1472 FIGVIIDNFNEQKKKA 1487
+GV+ F+++++KA
Sbjct: 404 VLGVLSGEFSKEREKA 419
Score = 60.1 bits (139), Expect = 6e-07
Identities = 30/95 (31%), Positives = 56/95 (58%), Gaps = 6/95 (6%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LR+FK+ + W +L+ L++ + +M ++ +L +L + I IF+++GMQ+FG + F
Sbjct: 645 LRIFKVTRHWQSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQVFGGKF-----NF 699
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWD 926
+ R F +F + + VF++L GE W M+D
Sbjct: 700 DETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYD 734
Score = 50.0 bits (114), Expect = 6e-04
Identities = 19/58 (32%), Positives = 37/58 (63%)
Query: 164 PTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDL 221
P +E+ E +F I+T E+ +K++A G + Y+R+ WN LDFV++ + ++ ++L
Sbjct: 141 PDLETVEHVFLVIFTIETFLKIIAYGLVAHQNAYVRNGWNMLDFVIVVVGLFSVVLEL 198
Score = 43.2 bits (97), Expect = 0.074
Identities = 39/162 (24%), Positives = 75/162 (46%), Gaps = 15/162 (9%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMPT--TPTVESTEVIFTGIYTFESAVKVMA 187
++ V Y LV L + T+ ++ + P T + + G +T E K+ +
Sbjct: 541 VKSVPFYWLV---IILVFLNTLTISSEHYMQPDWLTQVQDVANKVLLGCFTCEMMTKMYS 597
Query: 188 RGFILQPFTYLRDAWNWLD-FVVIALAYVTMGIDLGNLAAL-----RTFRVLRALKTVAI 241
G LQ Y +N D FVV T+ ++L ++ L R R+LR K
Sbjct: 598 LG--LQ--AYFVSLFNRFDCFVVCGGITETILVELAIMSPLGISVFRCVRLLRIFKVTRH 653
Query: 242 VPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
L +V +++ S+K++ +++L + +F+L+G+Q++ G
Sbjct: 654 WQSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQVFGG 695
Score = 42.3 bits (95), Expect = 0.13
Identities = 30/97 (30%), Positives = 49/97 (50%), Gaps = 5/97 (5%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
+R+ KL + L+ ++ AL + ++ ++ FI+AV+GMQ+FGK V VD
Sbjct: 1318 MRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGK--VAMVDGT 1375
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
NF F + +++FR GE W E M C+
Sbjct: 1376 HIN--RNNNFQTFPQAVLLLFRCATGEAWQEIMLACV 1410
Score = 41.5 bits (93), Expect = 0.23
Identities = 19/59 (32%), Positives = 36/59 (61%)
Query: 1630 LRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
++ +R +V R LRLV G ++ +L ++ ++ L +I LL+ V+ I+AI G+ F+
Sbjct: 239 VKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFI 297
Score = 40.7 bits (91), Expect = 0.40
Identities = 26/70 (37%), Positives = 40/70 (57%), Gaps = 7/70 (10%)
Query: 1554 TLDH--YQQSETFSAVLDYLNMIFIVIFSSECLLKIFA--LRYH---YFVEPWNLFDFVV 1606
T++H Y ++ T L+ + +F+VIF+ E LKI A L H Y WN+ DFV+
Sbjct: 127 TVEHVFYFETPTPQPDLETVEHVFLVIFTIETFLKIIAYGLVAHQNAYVRNGWNMLDFVI 186
Query: 1607 VMFSILSLVL 1616
V+ + S+VL
Sbjct: 187 VVVGLFSVVL 196
Score = 37.5 bits (83), Expect = 3.7
Identities = 16/57 (28%), Positives = 36/57 (63%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
KAL++ LR +L P+L ++++ + + M L ++ ++ +I I+A++G++LF
Sbjct: 240 KALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELF 296
>UniRef50_Q24270 Cluster: Voltage-dependent calcium channel type D
alpha-1 subunit; n=6; Coelomata|Rep: Voltage-dependent
calcium channel type D alpha-1 subunit - Drosophila
melanogaster (Fruit fly)
Length = 2516
Score = 304 bits (747), Expect = 1e-80
Identities = 204/675 (30%), Positives = 349/675 (51%), Gaps = 55/675 (8%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
L ++ F ++ I+ SS LA E+ L L +L D FT +F IE+++K ++
Sbjct: 1340 LCNHSNFGNIILCCIMFSSAMLAAENP-LRANDDLNKVLNKFDYFFTAVFTIELILKLIS 1398
Query: 1274 LGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSR 1329
GF + +A+ LD ++V VSLI+ V++ + I K +R LR LRPLRA++R
Sbjct: 1399 YGFVLHDGAFCRSAFNLLDLLVVCVSLISLVSS---SNAISVVKILRVLRVLRPLRAINR 1455
Query: 1330 MQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTL----- 1384
+G++ VV ++ A+ +I N++LV + +FA++GVQLF GK+FKC D + T
Sbjct: 1456 AKGLKHVVQCVIVAVKTIGNIVLVTCLLQFMFAVIGVQLFKGKFFKCTDGSKMTQDECYG 1515
Query: 1385 SHEIIPDKNACT--LENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVG 1442
++ + D + L W N+ +FD V K L LF V+TF+GW ++ +IDS +
Sbjct: 1516 TYLVYDDGDVHKPRLREREWSNNRFHFDDVAKGMLTLFTVSTFEGWPGLLYVSIDSNKEN 1575
Query: 1443 RQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKY 1502
PI + Y +N+F+G +I F + G E + K
Sbjct: 1576 GGPIHNFRPIVAAYYIIYIIIIAFFMVNIFVGFVIVTFQNE-----GEQEYKNCDLDKNQ 1630
Query: 1503 YNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSE 1562
N ++ KP++ P+ Q V+ VT F+ I + I +N +T+ + Y Q
Sbjct: 1631 RNCIEFALKAKPVRRYI-PKHGIQYKVWWFVTSSSFEYTIFILIMINTVTLAMKFYNQPL 1689
Query: 1563 TFSAVLDYLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSLVLS---- 1617
++ +LD LNMIF +F+ E + K+ A R+ +YF + WN+FDF++V+ S + +V S
Sbjct: 1690 WYTELLDALNMIFTAVFALEFVFKLAAFRFKNYFGDAWNVFDFIIVLGSFIDIVYSEIKS 1749
Query: 1618 ---------DIIE-----KYFVSPTLLRV--VRVAKVGRVLRLVKGAKGIRTLLFALAMS 1661
DI+E K L+ + R+ +V R+++L+ +GIRTLL+ S
Sbjct: 1750 KDTSQIAECDIVEGCKSTKKSAGSNLISINFFRLFRVMRLVKLLSKGEGIRTLLWTFIKS 1809
Query: 1662 LPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGG--LDDVYNFKTFVQSMILLFQMSTSA 1719
AL + LL+ L+ FI+A+ GM F + GG + NF+TF Q++++LF+ +T
Sbjct: 1810 FQALPYVALLIVLLFFIYAVVGMQVFGKIALDGGNAITANNNFQTFQQAVLVLFRSATGE 1869
Query: 1720 GWDGVLDGIINEEE--CDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVIL 1777
W ++ + + CD+ + G P CGS +I Y +S+ V+ ++IN+++AVI+
Sbjct: 1870 AWQEIMMSCSAQPDVKCDMNSDTPGEP--CGS-SIAYPYFISFYVLCSFLIINLFVAVIM 1926
Query: 1778 ENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHK--P 1835
+N+ T D L D + +W +DPD I++ + L + PPL K P
Sbjct: 1927 DNFDYLTRD-WSILGPHHLDEFIRLWSEYDPDAKGRIKHLDVVTLLRKISPPLGFGKLCP 1985
Query: 1836 NKY---KIISMDIPI 1847
++ +++SM++P+
Sbjct: 1986 HRMACKRLVSMNMPL 2000
Score = 136 bits (329), Expect = 6e-30
Identities = 96/312 (30%), Positives = 162/312 (51%), Gaps = 54/312 (17%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM----------PTTPTVEST 169
AL+ L NP+R + I I+ F I+ TI NCI + + T T+E
Sbjct: 594 ALFCLSVKNPLRALCIRIVEWKPFEFLILLTIFANCIALAVYTPYPGSDSNVTNQTLEKV 653
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-----DLGNL 224
E +F I+T E +K++A GF+L YLR+ WN LDF ++ + ++ + D ++
Sbjct: 654 EYVFLVIFTAECVMKILAYGFVLHNGAYLRNGWNLLDFTIVVIGAISTALSQLMKDAFDV 713
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
ALR FRVLR L+ V+ VP L+ ++ ++++++ L + +L +F + ++A++GL+++ G
Sbjct: 714 KALRAFRVLRPLRLVSGVPSLQVVLNSILKAMVPLFHIALLVLFVIIIYAIIGLELFSGK 773
Query: 285 LTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQ 344
L + C D G +EN R C G G P PGY C
Sbjct: 774 LHKAC-----RDEITGEY-EEN-IRPC-------GVGYQCP------------PGYKCYG 807
Query: 345 GFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWEN-LYQ-----------LFFVVIIFLGS 392
G+ PN G T+FD FG A L+ F+ +T + W + LY ++F+ ++ LG+
Sbjct: 808 GW-DGPNDGITNFDNFGLAMLTVFQCVTLEGWTDVLYSIQDAMGSDWQWMYFISMVILGA 866
Query: 393 FYLVNLILAIVA 404
F+++NLIL +++
Sbjct: 867 FFVMNLILGVLS 878
Score = 105 bits (252), Expect = 1e-20
Identities = 82/295 (27%), Positives = 141/295 (47%), Gaps = 24/295 (8%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHL-PHRPILQDILYYMDRIFTVIFFI 1265
LR +++E FE ++ I + +ALA+ + + L ++ +F VIF
Sbjct: 604 LRALCIRIVEWKPFEFLILLTIFANCIALAVYTPYPGSDSNVTNQTLEKVEYVFLVIFTA 663
Query: 1266 EMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRAL 1321
E ++K LA GF Y N W LDF IV++ I+ + K +R R L
Sbjct: 664 ECVMKILAYGFVLHNGAYLRNGWNLLDFTIVVIGAISTALSQLMKDAFDV-KALRAFRVL 722
Query: 1322 RPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK-CVDMN 1380
RPLR +S + ++VV+N++++A+ +F++ L+ L +I+AI+G++LF+GK K C D
Sbjct: 723 RPLRLVSGVPSLQVVLNSILKAMVPLFHIALLVLFVIIIYAIIGLELFSGKLHKACRDEI 782
Query: 1381 HTTLSHEIIP--DKNACT--LENYTWENSP----MNFDHVGKAYLCLFQVATFKGWIQIM 1432
I P C + Y + P NFD+ G A L +FQ T +GW ++
Sbjct: 783 TGEYEENIRPCGVGYQCPPGYKCYGGWDGPNDGITNFDNFGLAMLTVFQCVTLEGWTDVL 842
Query: 1433 NDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKA 1487
D+ +G + ++Y +NL +GV+ F++++ KA
Sbjct: 843 YSIQDA--MGSD-------WQWMYFISMVILGAFFVMNLILGVLSGEFSKERNKA 888
Score = 104 bits (250), Expect = 2e-20
Identities = 75/276 (27%), Positives = 141/276 (51%), Gaps = 19/276 (6%)
Query: 1512 KKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYL 1571
+K K R R + + V + F +I++ + LN + +HY Q + +Y
Sbjct: 961 RKMKKDFDRVNRRMRRACRKAVKSQAFYWLIIVLVFLNTGVLATEHYGQLDWLDNFQEYT 1020
Query: 1572 NMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLL 1630
N+ FI +F+ E LLK+++L + YFV +N FD VV+ SI +L++ + P +
Sbjct: 1021 NVFFIGLFTCEMLLKMYSLGFQGYFVSLFNRFDCFVVIGSITETLLTN---TGMMPPLGV 1077
Query: 1631 RVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHV 1690
V+R ++ RV ++ K + + L+ +L S+ ++ ++ LLLFL + IFA+ GM F
Sbjct: 1078 SVLRCVRLLRVFKVTKYWRSLSNLVASLLNSIQSIASLLLLLFLFIVIFALLGMQVFGGK 1137
Query: 1691 KDKGGLDDVY--NFKTFVQSMILLFQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNC 1747
+ G ++ Y NF F Q+++ +FQ+ T W+ V+ GI N G +
Sbjct: 1138 FNFDGKEEKYRMNFDCFWQALLTVFQIMTGEDWNAVMYVGI----------NAYGGVSSY 1187
Query: 1748 GSATIGITYLLSYLVISFLIVINMYIAVILENYSQA 1783
G+ + Y + + I++N+++A+ ++N + A
Sbjct: 1188 GA--LACIYFIILFICGNYILLNVFLAIAVDNLADA 1221
Score = 93.5 bits (222), Expect = 5e-17
Identities = 64/218 (29%), Positives = 114/218 (52%), Gaps = 17/218 (7%)
Query: 1526 QAIVFEIVTDKKFDMIIMLFIGLNMLTMTL-DHYQQSET--FSAVLDYLNMIFIVIFSSE 1582
+A+ IV K F+ +I+L I N + + + Y S++ + L+ + +F+VIF++E
Sbjct: 605 RALCIRIVEWKPFEFLILLTIFANCIALAVYTPYPGSDSNVTNQTLEKVEYVFLVIFTAE 664
Query: 1583 CLLKIFALRY--H---YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAK 1637
C++KI A + H Y WNL DF +V+ +S LS +++ F ++ +R +
Sbjct: 665 CVMKILAYGFVLHNGAYLRNGWNLLDFTIVVIGAISTALSQLMKDAFD----VKALRAFR 720
Query: 1638 VGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLD 1697
V R LRLV G ++ +L ++ ++ LF+I LL+ V+ I+AI G+ F K D
Sbjct: 721 VLRPLRLVSGVPSLQVVLNSILKAMVPLFHIALLVLFVIIIYAIIGLELFSGKLHKACRD 780
Query: 1698 DVY-NFKTFVQSMILLFQMSTS----AGWDGVLDGIIN 1730
++ ++ ++ + +Q GWDG DGI N
Sbjct: 781 EITGEYEENIRPCGVGYQCPPGYKCYGGWDGPNDGITN 818
Score = 78.6 bits (185), Expect = 2e-12
Identities = 75/302 (24%), Positives = 130/302 (43%), Gaps = 34/302 (11%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
K +++ F +I ++ L++ LA E H L + Y + F +F EML+K
Sbjct: 980 KAVKSQAFYWLIIVLVFLNTGVLATE--HYGQLDWLDNFQEYTNVFFIGLFTCEMLLKMY 1037
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG 1332
+LGFQ YF + + D +V+ S+ + G +R +R LR + +
Sbjct: 1038 SLGFQGYFVSLFNRFDCFVVIGSITETLLTNTGMMPPLGVSVLRCVRLLRVFKVTKYWRS 1097
Query: 1333 MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDK 1392
+ +V +L+ +I SI ++LL+ +F +IFA++G+Q+F GK+
Sbjct: 1098 LSNLVASLLNSIQSIASLLLLLFLFIVIFALLGMQVFGGKF------------------- 1138
Query: 1393 NACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIY 1452
N E E MNFD +A L +FQ+ T + W +M I++ +
Sbjct: 1139 NFDGKE----EKYRMNFDCFWQALLTVFQIMTGEDWNAVMYVGINA----YGGVSSYGAL 1190
Query: 1453 MYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSK 1512
+Y LN+F+ + +DN + SL E++ +A KK S
Sbjct: 1191 ACIYFIILFICGNYILLNVFLAIAVDNLAD-----ADSLSEVEKEEEPHDESAQKKSHSP 1245
Query: 1513 KP 1514
P
Sbjct: 1246 TP 1247
Score = 73.7 bits (173), Expect = 5e-11
Identities = 35/117 (29%), Positives = 70/117 (59%), Gaps = 3/117 (2%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA--- 226
+ FT ++T E +K+++ GF+L + R A+N LD +V+ ++ +++ ++
Sbjct: 1381 DYFFTAVFTIELILKLISYGFVLHDGAFCRSAFNLLDLLVVCVSLISLVSSSNAISVVKI 1440
Query: 227 LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
LR RVLR L+ + GLK +V VI +VK + +++++T +FA++G+Q++ G
Sbjct: 1441 LRVLRVLRPLRAINRAKGLKHVVQCVIVAVKTIGNIVLVTCLLQFMFAVIGVQLFKG 1497
Score = 56.0 bits (129), Expect = 1e-05
Identities = 46/148 (31%), Positives = 78/148 (52%), Gaps = 15/148 (10%)
Query: 782 LEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMD-KALKSGNYLRVFKLAK 840
L FQ Y L F+ F + F+ + + TL L + M + L+ LRVFK+ K
Sbjct: 1039 LGFQGYFVSL-FNRF-DCFVVIGSITETL---LTNTGMMPPLGVSVLRCVRLLRVFKVTK 1093
Query: 841 SWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDG--DLP 898
W +L+ L++ + ++ ++ +L +L + I IFA++GMQ+FG + F DG +
Sbjct: 1094 YWRSLSNLVASLLNSIQSIASLLLLLFLFIVIFALLGMQVFGGKF-----NF-DGKEEKY 1147
Query: 899 RWNFTDFMHSFMIVFRVLCGE-WIESMW 925
R NF F + + VF+++ GE W M+
Sbjct: 1148 RMNFDCFWQALLTVFQIMTGEDWNAVMY 1175
Score = 54.0 bits (124), Expect = 4e-05
Identities = 35/123 (28%), Positives = 63/123 (51%), Gaps = 10/123 (8%)
Query: 167 ESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLD-FVVIALAYVTMGIDLG--- 222
E T V F G++T E +K+ + GF Y +N D FVVI T+ + G
Sbjct: 1018 EYTNVFFIGLFTCEMLLKMYSLGFQ----GYFVSLFNRFDCFVVIGSITETLLTNTGMMP 1073
Query: 223 --NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
++ LR R+LR K L +V +++ S++++ +++L + +FAL+G+Q+
Sbjct: 1074 PLGVSVLRCVRLLRVFKVTKYWRSLSNLVASLLNSIQSIASLLLLLFLFIVIFALLGMQV 1133
Query: 281 YMG 283
+ G
Sbjct: 1134 FGG 1136
Score = 52.4 bits (120), Expect = 1e-04
Identities = 31/104 (29%), Positives = 52/104 (50%), Gaps = 5/104 (4%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
+R+ KL + L+ ++ AL + ++ ++ FI+AV+GMQ+FGK +D +
Sbjct: 1787 MRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIVLLFFIYAVVGMQVFGKIALDGGNAI 1846
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSC 935
+ NF F + +++FR GE W E M C DV C
Sbjct: 1847 TANN----NFQTFQQAVLVLFRSATGEAWQEIMMSCSAQPDVKC 1886
Score = 40.7 bits (91), Expect = 0.40
Identities = 20/77 (25%), Positives = 43/77 (55%)
Query: 805 IVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTF 864
+V+ + AL D KAL++ LR +L P+L ++++ + + M L ++
Sbjct: 694 VVIGAISTALSQLMKDAFDVKALRAFRVLRPLRLVSGVPSLQVVLNSILKAMVPLFHIAL 753
Query: 865 VLCIIIFIFAVMGMQLF 881
++ +I I+A++G++LF
Sbjct: 754 LVLFVIIIYAIIGLELF 770
>UniRef50_P91645 Cluster: Voltage-dependent calcium channel type A
alpha-1 subunit; n=21; Endopterygota|Rep:
Voltage-dependent calcium channel type A alpha-1 subunit
- Drosophila melanogaster (Fruit fly)
Length = 1851
Score = 303 bits (744), Expect = 3e-80
Identities = 193/655 (29%), Positives = 341/655 (52%), Gaps = 39/655 (5%)
Query: 1219 YFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGF-- 1276
YF+ ++ +I +SS+ALA ED + IL Y D FT +F IEML+K + LG
Sbjct: 770 YFDFFIMVVISMSSIALAAEDP-VRENSRRNKILNYFDYAFTGVFTIEMLLKIVDLGVIL 828
Query: 1277 --QKYFTNAWCWLDFIIVMVSLINFVAALCGAGG---IQAFKTMRTLRALRPLRAMSRMQ 1331
Y W +D ++V+ + ++F + G+ + K++R LR LRPL+ + R+
Sbjct: 829 HPGSYLREFWNIMDAVVVICAAVSFGFDMSGSSAGQNLSTIKSLRVLRVLRPLKTIKRVP 888
Query: 1332 GMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD-MNHTTLS----- 1385
++ V + +V ++ ++ N+L+V ++F IF+++GVQLF GK+F C D HT+
Sbjct: 889 KLKAVFDCVVNSLKNVVNILIVYILFQFIFSVIGVQLFNGKFFYCTDESKHTSAECQGSY 948
Query: 1386 HEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQP 1445
+ D+ E W+ ++D+V A L LF V T +GW Q++ ++ + R P
Sbjct: 949 FKYEEDELLPKQELRVWKPRAFHYDNVAAAMLTLFAVQTGEGWPQVLQHSMAATYEDRGP 1008
Query: 1446 IRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNA 1505
I+ I M ++ +N+F+ +II F EQ G E+ E K +
Sbjct: 1009 IQNFRIEMSIFYIVYFIVFPFFFVNIFVALIIITFQEQ-----GEAELQDGEIDKNQKSC 1063
Query: 1506 MKKMGSKKPL-KAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETF 1564
+ +PL + +P+ R + V+ IV F+ IM+ I N L + + ++ Q + +
Sbjct: 1064 IDFTIGARPLERYMPKNRNTFKYKVWRIVVSTPFEYFIMMLIVFNTLLLMMKYHNQGDMY 1123
Query: 1565 SAVLDYLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSLVLSDI--IE 1621
L Y+NM F +FS E +LKI ++F +PWN+FD + V+ SI+ + + +
Sbjct: 1124 EKSLKYINMGFTGMFSVETVLKIIGFGVKNFFKDPWNIFDLITVLGSIVDALWMEFGHDD 1183
Query: 1622 KYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAI 1681
++ LR+ R A R+++L++ IR LL+ S AL +CLL+ ++ FI+AI
Sbjct: 1184 SNSINVGFLRLFRAA---RLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAI 1240
Query: 1682 FGMSFFMHVK---DKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPD 1738
GM F ++K + + NF++F+Q ++LLF+ +T W ++ + + CD D
Sbjct: 1241 IGMQVFGNIKLGTVENSITRHNNFQSFIQGVMLLFRCATGEAWPNIMLACLKGKACD--D 1298
Query: 1739 NERGSPGN-CGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYD 1797
+ +PG CGS T+ Y +S++ +++N+++AVI++N+ T D L D
Sbjct: 1299 DAEKAPGEYCGS-TLAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRD-SSILGAHHLD 1356
Query: 1798 MYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHK--PNKY---KIISMDIPI 1847
+ IW +DP+ + I Y ++ D L ++PPL PN+ K+I M++P+
Sbjct: 1357 EFVRIWAEYDPNATGKIHYTEMYDMLKNMDPPLGFGNKCPNRLAYKKLIRMNMPL 1411
Score = 147 bits (356), Expect = 3e-33
Identities = 92/310 (29%), Positives = 165/310 (53%), Gaps = 38/310 (12%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT----------TPTVEST 169
+L+IL NPIR+ +I+ P F ++ TI+ NC+++ + +E T
Sbjct: 17 SLFILTEDNPIRKYTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPGGDKTVLAQKLEKT 76
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLG---NLAA 226
E F I+ E+++K++A G +L +YLR+ WN +DF V+ ++T +G +L
Sbjct: 77 EAYFLCIFCVEASLKILALGLVLHKHSYLRNIWNIMDFFVVVTGFMTQYPQIGPEVDLRT 136
Query: 227 LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLT 286
LR RVLR LK V+ +P L+ ++ ++I+++ L + +L +F++ +FA++GL+ Y G L
Sbjct: 137 LRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALH 196
Query: 287 QKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGF 346
+ C + ED + L E N N + +C N++ +CL+ +
Sbjct: 197 KTCYSL--EDPN--KLVKEGESETPCNTDNILEKATGSFVCNNTTS--------MCLEKW 244
Query: 347 GPNPNYGYTSFDTFGWAFLSAFRLMTQD------YWEN------LYQLFFVVIIFLGSFY 394
PN G TSFD G+A L+ F+ +T + YW N ++FV +I +GSF+
Sbjct: 245 -EGPNSGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSAFNWIYFVPLIVIGSFF 303
Query: 395 LVNLILAIVA 404
++NL+L +++
Sbjct: 304 MLNLVLGVLS 313
Score = 108 bits (260), Expect = 1e-21
Identities = 61/182 (33%), Positives = 104/182 (57%), Gaps = 17/182 (9%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM--PTTPTVESTEVI---- 172
++++IL P NPIRR A +++ P F FI+ I ++ I + P +++
Sbjct: 747 SSMFILSPTNPIRRGAHWVVNLPYFDFFIMVVISMSSIALAAEDPVRENSRRNKILNYFD 806
Query: 173 --FTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID---------L 221
FTG++T E +K++ G IL P +YLR+ WN +D VV+ A V+ G D L
Sbjct: 807 YAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMDAVVVICAAVSFGFDMSGSSAGQNL 866
Query: 222 GNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+ +LR RVLR LKT+ VP LK + V+ S+KN+ +++I+ + +F+++G+Q++
Sbjct: 867 STIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVVNILIVYILFQFIFSVIGVQLF 926
Query: 282 MG 283
G
Sbjct: 927 NG 928
Score = 100 bits (239), Expect = 5e-19
Identities = 68/250 (27%), Positives = 124/250 (49%), Gaps = 19/250 (7%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFV 1596
F +++ + LN + + ++HY Q + L Y IF+ +F SE +K++AL YF
Sbjct: 443 FYWFVIVLVFLNTVCVAVEHYGQPSFLTEFLYYAEFIFLGLFMSEMFIKMYALGPRIYFE 502
Query: 1597 EPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLF 1656
+N FD VV+ SI ++ S++ F L V+R ++ R+ ++ K +R L+
Sbjct: 503 SSFNRFDCVVISGSIFEVIWSEVKGGSFG----LSVLRALRLLRIFKVTKYWSSLRNLVI 558
Query: 1657 ALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMS 1716
+L S+ ++ ++ LLFL + IFA+ GM F + G NF TF +++ +FQ+
Sbjct: 559 SLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQFNLPGGTPETNFNTFPIALLTVFQIL 618
Query: 1717 TSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAV 1775
T W+ V+ GII S G I Y + ++ ++N+++A+
Sbjct: 619 TGEDWNEVMYQGII-------------SQGGAQKGMIYSIYFIVLVLFGNYTLLNVFLAI 665
Query: 1776 ILENYSQATE 1785
++N + A E
Sbjct: 666 AVDNLANAQE 675
Score = 95.1 bits (226), Expect = 2e-17
Identities = 88/332 (26%), Positives = 154/332 (46%), Gaps = 48/332 (14%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLP--HRPILQDILYYMDRIFTVIFF 1264
+R T +IE FE AV+ I+ + + LALE+ HLP + +L L + F IF
Sbjct: 27 IRKYTRFIIEWPPFEYAVLLTIIANCVVLALEE-HLPGGDKTVLAQKLEKTEAYFLCIFC 85
Query: 1265 IEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRA 1320
+E +K LALG Y N W +DF +V+ F+ G +T+R +R
Sbjct: 86 VEASLKILALGLVLHKHSYLRNIWNIMDFFVVVTG---FMTQYPQIGPEVDLRTLRAIRV 142
Query: 1321 LRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK-CVDM 1379
LRPL+ +S + ++VV+ ++++A+ + + L+ L +IFAI+G++ ++G K C +
Sbjct: 143 LRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHKTCYSL 202
Query: 1380 -----------NHTTLSHEIIPDK----------NACTLENYTWENSPM-NFDHVGKAYL 1417
+ T + + I +K + LE + NS + +FD++G A L
Sbjct: 203 EDPNKLVKEGESETPCNTDNILEKATGSFVCNNTTSMCLEKWEGPNSGITSFDNIGFAML 262
Query: 1418 CLFQVATFKGWIQIM---NDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIG 1474
+FQ T +GW I+ NDA+ S + ++Y LNL +G
Sbjct: 263 TVFQCITMEGWTAILYWTNDALGS------------AFNWIYFVPLIVIGSFFMLNLVLG 310
Query: 1475 VIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAM 1506
V+ F+ ++ + +E + + AM
Sbjct: 311 VLSGEFSNERNRVERRMEFQKCRFRAMFQTAM 342
Score = 92.7 bits (220), Expect = 9e-17
Identities = 78/309 (25%), Positives = 139/309 (44%), Gaps = 34/309 (11%)
Query: 1200 FWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIF 1259
FW+ R ++ +F VI ++ L+++ +A+E H L + LYY + IF
Sbjct: 423 FWRAEKRFRFWIRHTVKTQWFYWFVIVLVFLNTVCVAVE--HYGQPSFLTEFLYYAEFIF 480
Query: 1260 TVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLR 1319
+F EM IK ALG + YF +++ D +++ S+ + + GG +R LR
Sbjct: 481 LGLFMSEMFIKMYALGPRIYFESSFNRFDCVVISGSIFEVIWSEV-KGGSFGLSVLRALR 539
Query: 1320 ALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDM 1379
LR + +R +V +L+ ++ SI ++L + +F LIFA++G+QLF G++
Sbjct: 540 LLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQF------ 593
Query: 1380 NHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSR 1439
N NF+ A L +FQ+ T + W ++M I S
Sbjct: 594 -------------------NLPGGTPETNFNTFPIALLTVFQILTGEDWNEVMYQGIIS- 633
Query: 1440 EVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQ 1499
+ G Q + IY +Y LN+F+ + +DN ++ E + ED+
Sbjct: 634 QGGAQ---KGMIYS-IYFIVLVLFGNYTLLNVFLAIAVDNLANAQELTAAEEEQ-VEEDK 688
Query: 1500 KKYYNAMKK 1508
+K ++K
Sbjct: 689 EKQLQELEK 697
Score = 65.3 bits (152), Expect = 2e-08
Identities = 40/101 (39%), Positives = 62/101 (61%), Gaps = 9/101 (8%)
Query: 827 LKSGNYLRVFKLAKSWPTL-NLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY 885
L++ LR+FK+ K W +L NL+IS++ +M ++ +L F+L + I IFA++GMQLFG +
Sbjct: 535 LRALRLLRIFKVTKYWSSLRNLVISLLN-SMRSIISLLFLLFLFILIFALLGMQLFGGQF 593
Query: 886 VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMW 925
P G P NF F + + VF++L GE W E M+
Sbjct: 594 -----NLP-GGTPETNFNTFPIALLTVFQILTGEDWNEVMY 628
Score = 52.0 bits (119), Expect = 2e-04
Identities = 34/132 (25%), Positives = 64/132 (48%), Gaps = 4/132 (3%)
Query: 798 ELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMG 857
+L L +V+ L+M H + + L+ R+ KL + T+ +L+ ++
Sbjct: 1163 DLITVLGSIVDALWMEFGHDDSNSINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFK 1222
Query: 858 ALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLC 917
AL + ++ ++ FI+A++GMQ+FG + V+ + NF F+ M++FR
Sbjct: 1223 ALPYVCLLIAMLFFIYAIIGMQVFGNIKLGTVE---NSITRHNNFQSFIQGVMLLFRCAT 1279
Query: 918 GE-WIESMWDCM 928
GE W M C+
Sbjct: 1280 GEAWPNIMLACL 1291
Score = 51.6 bits (118), Expect = 2e-04
Identities = 39/153 (25%), Positives = 76/153 (49%), Gaps = 16/153 (10%)
Query: 143 FSLFIITTILVNCILMIM-----PT--TPTVESTEVIFTGIYTFESAVKVMARGFILQPF 195
F F+I + +N + + + P+ T + E IF G++ E +K+ A G P
Sbjct: 443 FYWFVIVLVFLNTVCVAVEHYGQPSFLTEFLYYAEFIFLGLFMSEMFIKMYALG----PR 498
Query: 196 TYLRDAWNWLDFVVIA---LAYVTMGIDLGN--LAALRTFRVLRALKTVAIVPGLKTIVG 250
Y ++N D VVI+ + + G+ L+ LR R+LR K L+ +V
Sbjct: 499 IYFESSFNRFDCVVISGSIFEVIWSEVKGGSFGLSVLRALRLLRIFKVTKYWSSLRNLVI 558
Query: 251 AVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
+++ S++++ ++ L + +FAL+G+Q++ G
Sbjct: 559 SLLNSMRSIISLLFLLFLFILIFALLGMQLFGG 591
Score = 47.2 bits (107), Expect = 0.005
Identities = 43/162 (26%), Positives = 74/162 (45%), Gaps = 22/162 (13%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQ---QSETFSAVLDYLNMIFIVIFSSECLLKIFAL---- 1590
F+ ++L I N + + L+ + + L+ F+ IF E LKI AL
Sbjct: 40 FEYAVLLTIIANCVVLALEEHLPGGDKTVLAQKLEKTEAYFLCIFCVEASLKILALGLVL 99
Query: 1591 -RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTL-LRVVRVAKVGRVLRLVKGA 1648
++ Y WN+ DF VV+ ++ + P + LR +R +V R L+LV G
Sbjct: 100 HKHSYLRNIWNIMDFFVVVTGFMTQYPQ-------IGPEVDLRTLRAIRVLRPLKLVSGI 152
Query: 1649 KGIRTLLFALAMSLPALFNICLLLFLVMFIFAIF---GMSFF 1687
++ +L ++ ++ L I LL V+F IF G+ F+
Sbjct: 153 PSLQVVLKSIIKAMAPLLQIGLL---VLFAIVIFAIIGLEFY 191
>UniRef50_Q7PQV4 Cluster: ENSANGP00000003024; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000003024 - Anopheles gambiae
str. PEST
Length = 2264
Score = 303 bits (743), Expect = 4e-80
Identities = 176/616 (28%), Positives = 330/616 (53%), Gaps = 37/616 (6%)
Query: 1215 IENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLAL 1274
+ +F+ ++ I L+ + LA+E ++P + L + +FT +F +EM IK ++
Sbjct: 1626 VNQKWFDNVILLFIALNCITLAMERPNIPPNCTERYFLATANYVFTGVFAVEMFIKVVSA 1685
Query: 1275 GF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAF---KTMRTLRALRPLRAM 1327
G YFT+ W +D +V +S+++ + +L + F + R LR+LRPLR +
Sbjct: 1686 GLFYGPDAYFTSGWNIMDGSLVTISIVDLLMSLISESSPRIFGILRVFRLLRSLRPLRVI 1745
Query: 1328 SRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHE 1387
+R G+++VV L+ ++ I N++L+C F++IF I+GVQLF G ++ C N + ++
Sbjct: 1746 NRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGTFYYCEGENIKGVKNK 1805
Query: 1388 IIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIR 1447
++ +E W N NFD +GKA + LF +++ GW+ IM +D+ V +QPI
Sbjct: 1806 ----QDCLAIEGNVWINRKYNFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQPIV 1861
Query: 1448 ETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMK 1507
N + LY LN+F+GV+++NF+ +++ E ++K A K
Sbjct: 1862 NYNEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCREE---------QEKEEKIRRAAK 1912
Query: 1508 K-MGSKKPLKAIPRP----RWRPQAI-VFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQS 1561
+ + +K K + P + P + V +VT K FD+ I IGLN++TM +++Y
Sbjct: 1913 RALQMEKKRKRMHEPPYYTNYSPMRLFVHNVVTSKYFDLAIAAVIGLNVVTMAMEYYMMP 1972
Query: 1562 ETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDII 1620
L N F +F E +K+ AL Y + WN D +V+ SI+ +VL ++
Sbjct: 1973 LALEYALKIFNYFFTAVFILEAAMKLLALGVKIYMKDRWNQLDVAIVILSIVGIVLEELE 2032
Query: 1621 EKYF-VSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIF 1679
++PT++RV+RV ++ RVL+L+K AKGIR LL + +LP + N+ LL FL+ FIF
Sbjct: 2033 TNIIPINPTIIRVMRVLRIARVLKLLKMAKGIRALLDTVMQALPQVGNLGLLFFLLFFIF 2092
Query: 1680 AIFGMSFF--MHVKDK---GGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEEC 1734
A G+ F + D+ GL + +F F + + LF+++T W+G++ + ++
Sbjct: 2093 AALGVELFGRLECSDEVPCQGLGEHAHFANFGMAFLTLFRVATGDNWNGIMKDTLRDDCD 2152
Query: 1735 DLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGL-TD 1793
D D + C S I + + +++++ +++N+ +AV++++ ++ + +++ L +
Sbjct: 2153 DAADCVKNC---CVSTIIAPIFFVIFVLMAQFVLVNVVVAVLMKHLEESHKQMEDDLDIE 2209
Query: 1794 DDYDMYYEIWQRFDPD 1809
+ + +E Q F+ +
Sbjct: 2210 TELEREFEREQEFEEE 2225
Score = 97.1 bits (231), Expect = 4e-18
Identities = 77/314 (24%), Positives = 150/314 (47%), Gaps = 31/314 (9%)
Query: 1197 DSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMD 1256
+ P++ + +RL ++ + YF+ A+ +I L+ + +A+E +P L+ L +
Sbjct: 1926 EPPYYTNYSPMRLFVHNVVTSKYFDLAIAAVIGLNVVTMAMEYYMMP--LALEYALKIFN 1983
Query: 1257 RIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGI----QAF 1312
FT +F +E +K LALG + Y + W LD IV++S++ V I
Sbjct: 1984 YFFTAVFILEAAMKLLALGVKIYMKDRWNQLDVAIVILSIVGIVLEELETNIIPINPTII 2043
Query: 1313 KTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGK 1372
+ MR LR R L+ + +G+R +++ ++QA+P + N+ L+ + + IFA +GV+LF G+
Sbjct: 2044 RVMRVLRIARVLKLLKMAKGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELF-GR 2102
Query: 1373 YFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIM 1432
+C D +P + +F + G A+L LF+VAT W IM
Sbjct: 2103 -LECSDE---------VPCQGL---------GEHAHFANFGMAFLTLFRVATGDNWNGIM 2143
Query: 1433 NDAI-DSREVGRQPIRE---TNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAG 1488
D + D + ++ + I ++ +N+ + V++ + E K+
Sbjct: 2144 KDTLRDDCDDAADCVKNCCVSTIIAPIFFVIFVLMAQFVLVNVVVAVLMKHLEESHKQME 2203
Query: 1489 GSLEMFMTEDQKKY 1502
L++ TE ++++
Sbjct: 2204 DDLDI-ETELEREF 2216
Score = 90.6 bits (215), Expect = 4e-16
Identities = 61/207 (29%), Positives = 114/207 (55%), Gaps = 9/207 (4%)
Query: 1526 QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLL 1585
+ +V ++V K F I+L I +N L+M ++++ Q +A+++ N++F IF+ E +L
Sbjct: 838 RVLVKKLVDHKYFQQGILLAILINTLSMGIEYHDQPAELTAIVETSNIVFSAIFAVEMIL 897
Query: 1586 KIFAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRL 1644
K+ A + Y +N+FD V+V+ S++ L S + E S L V+R ++ R+L+L
Sbjct: 898 KVIAEGPFRYVANGFNVFDGVIVILSVVELGQSYLGEGQGSSG--LSVLRTFRLLRILKL 955
Query: 1645 VKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF-----MHVKDKGGLD-D 1698
V+ +R LF + ++ + LL L +FIF+I GM+ F + G ++ D
Sbjct: 956 VRFMPNLRRQLFVMLRTMDNVAIFFSLLILFIFIFSILGMNLFGCKFCEKNETAGEVECD 1015
Query: 1699 VYNFKTFVQSMILLFQMSTSAGWDGVL 1725
NF + + +++ +FQ+ T W+ VL
Sbjct: 1016 RKNFDSLLWALVTVFQILTQEDWNVVL 1042
Score = 86.2 bits (204), Expect = 8e-15
Identities = 53/159 (33%), Positives = 84/159 (52%), Gaps = 9/159 (5%)
Query: 1218 TYFETAVITMILLSSLALALEDVHLPHRPILQ--DILYYMDRIFTVIFFIEMLIKWLALG 1275
T+FE + +ILL+ + L + + + IL D I F +EM IK +A+G
Sbjct: 6 TWFERISMLVILLNCVTLGMYQPCVDDACVTNRCKILQIFDDIIFAFFSLEMTIKIVAMG 65
Query: 1276 FQ---KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG 1332
Y ++W LDF IV+ + + + +RT+R LRPLRA++R+
Sbjct: 66 AWGKGTYLADSWNRLDFFIVLAGALEYCLQVENLN----LTAIRTIRVLRPLRAINRIPS 121
Query: 1333 MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
MR++V L+ +P + NVLL+C + IF I+GVQL+ G
Sbjct: 122 MRILVMLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWEG 160
Score = 85.0 bits (201), Expect = 2e-14
Identities = 45/132 (34%), Positives = 81/132 (61%), Gaps = 6/132 (4%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVI---ALAYVTMGIDLGNLAA 226
++IF ++ E +K++A G TYL D+WN LDF ++ AL Y +L NL A
Sbjct: 47 DIIFA-FFSLEMTIKIVAMG-AWGKGTYLADSWNRLDFFIVLAGALEYCLQVENL-NLTA 103
Query: 227 LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLT 286
+RT RVLR L+ + +P ++ +V +++++ L +V++L F +F ++G+Q++ G+L
Sbjct: 104 IRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWEGILR 163
Query: 287 QKCVKVFPEDGS 298
Q+CV P++ S
Sbjct: 164 QRCVIKLPDNVS 175
Score = 81.8 bits (193), Expect = 2e-13
Identities = 64/280 (22%), Positives = 137/280 (48%), Gaps = 32/280 (11%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEM 1267
R+ KL+++ YF+ ++ IL+++L++ +E P L I+ + +F+ IF +EM
Sbjct: 838 RVLVKKLVDHKYFQQGILLAILINTLSMGIEYHDQPAE--LTAIVETSNIVFSAIFAVEM 895
Query: 1268 LIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAG-GIQAFKTMRTLRALRPLRA 1326
++K +A G +Y N + D +IV++S++ + G G G +RT R LR L+
Sbjct: 896 ILKVIAEGPFRYVANGFNVFDGVIVILSVVELGQSYLGEGQGSSGLSVLRTFRLLRILKL 955
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH 1386
+ M +R + +++ + ++ + ++F IF+I+G+ LF K+ C + N T +
Sbjct: 956 VRFMPNLRRQLFVMLRTMDNVAIFFSLLILFIFIFSILGMNLFGCKF--C-EKNET--AG 1010
Query: 1387 EIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPI 1446
E+ D+ NFD + A + +FQ+ T + W ++ + ++
Sbjct: 1011 EVECDRK--------------NFDSLLWALVTVFQILTQEDWNVVLFNGME--------- 1047
Query: 1447 RETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
+T+ + LY NL + ++++ F+ ++ +
Sbjct: 1048 -KTSHWAALYFVTLMTFGNYVLFNLLVAILVEGFSSERNE 1086
Score = 72.5 bits (170), Expect = 1e-10
Identities = 42/175 (24%), Positives = 88/175 (50%), Gaps = 18/175 (10%)
Query: 127 FNPIRRVAIYILVHPLFSLFIITTILVNCILMIM--PTTPT-------VESTEVIFTGIY 177
F R++ + + F I+ I +NCI + M P P + + +FTG++
Sbjct: 1615 FCRFRQICSWFVNQKWFDNVILLFIALNCITLAMERPNIPPNCTERYFLATANYVFTGVF 1674
Query: 178 TFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN------LAALRTFR 231
E +KV++ G P Y WN +D ++ ++ V + + L + LR FR
Sbjct: 1675 AVEMFIKVVSAGLFYGPDAYFTSGWNIMDGSLVTISIVDLLMSLISESSPRIFGILRVFR 1734
Query: 232 VLRALKTVAIV---PGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
+LR+L+ + ++ PGLK +V ++ S++ + +++++ +F ++G+Q++ G
Sbjct: 1735 LLRSLRPLRVINRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKG 1789
Score = 70.9 bits (166), Expect = 3e-10
Identities = 49/167 (29%), Positives = 89/167 (53%), Gaps = 19/167 (11%)
Query: 130 IRRVAIYILV-HPLFSLFIITTILVNCILMIMP-------TTPTVESTEVIFTGIYTFES 181
+ RV + LV H F I+ IL+N + M + T VE++ ++F+ I+ E
Sbjct: 836 LTRVLVKKLVDHKYFQQGILLAILINTLSMGIEYHDQPAELTAIVETSNIVFSAIFAVEM 895
Query: 182 AVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID-LGN------LAALRTFRVLR 234
+KV+A G PF Y+ + +N D V++ L+ V +G LG L+ LRTFR+LR
Sbjct: 896 ILKVIAEG----PFRYVANGFNVFDGVIVILSVVELGQSYLGEGQGSSGLSVLRTFRLLR 951
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
LK V +P L+ + ++ ++ N+ L + + +F+++G+ ++
Sbjct: 952 ILKLVRFMPNLRRQLFVMLRTMDNVAIFFSLLILFIFIFSILGMNLF 998
Score = 59.7 bits (138), Expect = 8e-07
Identities = 51/160 (31%), Positives = 75/160 (46%), Gaps = 19/160 (11%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAV------LDYLNMIFIVIFSSECLLKIFAL- 1590
F+ I ML I LN +T+ + YQ + V L + I FS E +KI A+
Sbjct: 8 FERISMLVILLNCVTLGM--YQPCVDDACVTNRCKILQIFDDIIFAFFSLEMTIKIVAMG 65
Query: 1591 ---RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKG 1647
+ Y + WN DF +V+ L L +E ++ T +R +RV R LR +
Sbjct: 66 AWGKGTYLADSWNRLDFFIVLAGALEYCLQ--VEN--LNLTAIRTIRVL---RPLRAINR 118
Query: 1648 AKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+R L+ L +LP L N+ LL F V FIF I G+ +
Sbjct: 119 IPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLW 158
Score = 54.4 bits (125), Expect = 3e-05
Identities = 28/93 (30%), Positives = 50/93 (53%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L++ LR+ KL + P L + +M RTM + +L + IFIF+++GM LFG +
Sbjct: 944 LRTFRLLRILKLVRFMPNLRRQLFVMLRTMDNVAIFFSLLILFIFIFSILGMNLFGCKFC 1003
Query: 887 DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE 919
+ + + + R NF + + + VF++L E
Sbjct: 1004 EKNETAGEVECDRKNFDSLLWALVTVFQILTQE 1036
Score = 54.0 bits (124), Expect = 4e-05
Identities = 37/172 (21%), Positives = 84/172 (48%), Gaps = 21/172 (12%)
Query: 127 FNPIRRVAIYILVHPLFSLFIITTILVNCILM-----IMPTTP--TVESTEVIFTGIYTF 179
++P+R ++ F L I I +N + M +MP ++ FT ++
Sbjct: 1933 YSPMRLFVHNVVTSKYFDLAIAAVIGLNVVTMAMEYYMMPLALEYALKIFNYFFTAVFIL 1992
Query: 180 ESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV----------TMGIDLGNLAALRT 229
E+A+K++A G + Y++D WN LD ++ L+ V + I+ + +R
Sbjct: 1993 EAAMKLLALGVKI----YMKDRWNQLDVAIVILSIVGIVLEELETNIIPINPTIIRVMRV 2048
Query: 230 FRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
R+ R LK + + G++ ++ V++++ + ++ +L +FA +G++++
Sbjct: 2049 LRIARVLKLLKMAKGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELF 2100
Score = 47.6 bits (108), Expect = 0.003
Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 4/97 (4%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
RV KL K + L+ + + + +GNL + ++ FIFA +G++LFG+ ++ D P
Sbjct: 2053 RVLKLLKMAKGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELFGR--LECSDEVP 2110
Query: 894 -DGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
G +F +F +F+ +FRV G+ W M D +
Sbjct: 2111 CQGLGEHAHFANFGMAFLTLFRVATGDNWNGIMKDTL 2147
Score = 44.4 bits (100), Expect = 0.032
Identities = 23/77 (29%), Positives = 43/77 (55%), Gaps = 12/77 (15%)
Query: 342 CLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ-----------LFFVVIIFL 390
C Q G NP G SFD G A+++ F +++ + W ++ ++FV++I +
Sbjct: 246 CTQ-LGNNPFQGTISFDNIGLAWVAIFLVISLEGWTDIMYYVQDAHSFWDWIYFVLLIVI 304
Query: 391 GSFYLVNLILAIVAMSY 407
GSF+++NL L ++A +
Sbjct: 305 GSFFMINLCLVVIATQF 321
Score = 38.7 bits (86), Expect = 1.6
Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
Query: 826 ALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF-GKN 884
A+++ LR + P++ +L+ ++ T+ LGN+ + + FIF ++G+QL+ G
Sbjct: 103 AIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWEGIL 162
Query: 885 YVDYVDRFPDGDLPRWNFTDFMHSF 909
V + PD P F + F
Sbjct: 163 RQRCVIKLPDNVSPPSYLVSFYYEF 187
Score = 36.7 bits (81), Expect = 6.4
Identities = 14/49 (28%), Positives = 27/49 (55%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
LR ++ P L L++ + ++ +GN+ + C IF ++G+QLF
Sbjct: 1739 LRPLRVINRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLF 1787
>UniRef50_UPI00015B53F6 Cluster: PREDICTED: similar to voltage- gated
calcium channel alpha subunit cav3.3 (voltage-dependent
t-type calcium channel; n=2; Apocrita|Rep: PREDICTED:
similar to voltage- gated calcium channel alpha subunit
cav3.3 (voltage-dependent t-type calcium channel -
Nasonia vitripennis
Length = 2080
Score = 300 bits (736), Expect = 3e-79
Identities = 174/623 (27%), Positives = 333/623 (53%), Gaps = 43/623 (6%)
Query: 1215 IENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLAL 1274
++ +F+ V+ I L+ + LA+E ++P + L + IFT +F +EM +K +A
Sbjct: 1456 VDQKWFDNVVLLFIGLNCITLAMERPNIPPDSRERLFLASANYIFTAVFAVEMFVKVVAT 1515
Query: 1275 GF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAF---KTMRTLRALRPLRAM 1327
G YFT+ W +D +V++S+I+ +L + + F + R LR+LRPLR +
Sbjct: 1516 GMLYGSDAYFTSGWNIMDGSLVVISIIDLGMSLLSSSSPRIFGILRVFRLLRSLRPLRVI 1575
Query: 1328 SRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKC--VDMNHTTLS 1385
+R G+++VV L+ ++ I N++L+C F++IF I+GVQLF G ++ C D+ +
Sbjct: 1576 NRAPGLKLVVQTLLSSLRPIGNIVLICCTFFVIFGILGVQLFKGAFYYCDGPDIKNVRNK 1635
Query: 1386 HEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQP 1445
+ + DK W N NFD +GKA + LF +++ GW+ IM +D+ V +QP
Sbjct: 1636 TDCLADK------RNVWLNRKYNFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQP 1689
Query: 1446 IRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNA 1505
I + + LY LN+F+GV+++NF+ +++ ++++ A
Sbjct: 1690 IENYSEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCREE--------QEKEERVRRAA 1741
Query: 1506 MKKMGSKKPLKAIPRPRW-----RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQ 1560
+ + +K + + P + + + + +VT K FD+ I IGLN++TM ++ Y
Sbjct: 1742 KRALQMEKKRRKMHEPPYYTNYSKTRLFIHNVVTSKYFDLAIAAVIGLNVVTMAMEFYMM 1801
Query: 1561 SETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDI 1619
+ + L N F +F E +K+ AL H Y + WN D +V+ S++ +VL ++
Sbjct: 1802 PKALTYALKIFNYFFTAVFILESFMKLLALGLHLYLKDKWNQLDIGIVILSVVGIVLEEL 1861
Query: 1620 IEKYF-VSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFI 1678
K ++PT++RV+RV ++ RVL+L+K AKGIR LL + +LP + N+ LL FL+ FI
Sbjct: 1862 ESKIIPINPTIIRVMRVLRIARVLKLLKMAKGIRALLDTVMQALPQVGNLGLLFFLLFFI 1921
Query: 1679 FAIFGMSFF--MHVKDK---GGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEE 1733
FA G+ F + D+ GL + +F F + + LF+++T W+G++ + +
Sbjct: 1922 FAALGVELFGRLECSDEMPCQGLGEHAHFSNFGMAFLTLFRVATGDNWNGIMKDTLRDNC 1981
Query: 1734 CDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTD 1793
D D + C S I + + +++++ +++N+ +AV++++ ++ + + +
Sbjct: 1982 DDAADCVKNC---CVSNIIAPIFFVIFVLMAQFVLVNVVVAVLMKHLEESHKQM-----E 2033
Query: 1794 DDYDMYYEIWQRFDPDGSQYIRY 1816
D+ DM ++ + F + + + +
Sbjct: 2034 DELDMETQLEREFAAEQEELLEF 2056
Score = 98.3 bits (234), Expect = 2e-18
Identities = 77/305 (25%), Positives = 144/305 (47%), Gaps = 30/305 (9%)
Query: 1197 DSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMD 1256
+ P++ + RL ++ + YF+ A+ +I L+ + +A+E +P L L +
Sbjct: 1756 EPPYYTNYSKTRLFIHNVVTSKYFDLAIAAVIGLNVVTMAMEFYMMP--KALTYALKIFN 1813
Query: 1257 RIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGI----QAF 1312
FT +F +E +K LALG Y + W LD IV++S++ V + I
Sbjct: 1814 YFFTAVFILESFMKLLALGLHLYLKDKWNQLDIGIVILSVVGIVLEELESKIIPINPTII 1873
Query: 1313 KTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGK 1372
+ MR LR R L+ + +G+R +++ ++QA+P + N+ L+ + + IFA +GV+LF G+
Sbjct: 1874 RVMRVLRIARVLKLLKMAKGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELF-GR 1932
Query: 1373 YFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIM 1432
+C D +P + +F + G A+L LF+VAT W IM
Sbjct: 1933 -LECSDE---------MPCQGL---------GEHAHFSNFGMAFLTLFRVATGDNWNGIM 1973
Query: 1433 NDAI-DSREVGRQPIRE---TNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAG 1488
D + D+ + ++ +NI ++ +N+ + V++ + E K+
Sbjct: 1974 KDTLRDNCDDAADCVKNCCVSNIIAPIFFVIFVLMAQFVLVNVVVAVLMKHLEESHKQME 2033
Query: 1489 GSLEM 1493
L+M
Sbjct: 2034 DELDM 2038
Score = 92.3 bits (219), Expect = 1e-16
Identities = 56/163 (34%), Positives = 87/163 (53%), Gaps = 9/163 (5%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQ--DILYYMDRIFTVIFFIEMLIKW 1271
LI N +FE + +ILL+ + L + + + + IL D I F +EM IK
Sbjct: 72 LITNPWFERISMMVILLNCITLGMYQPCVDDQCVTNRCKILQMFDDIIFAFFSLEMTIKM 131
Query: 1272 LALGFQ---KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMS 1328
+A+G Y ++W LDF IV+ + + C +RT+R LRPLRA++
Sbjct: 132 VAMGIYGKGTYLADSWNRLDFFIVLAGSLEY----CLNVENMNLSAIRTIRVLRPLRAIN 187
Query: 1329 RMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
R+ MR++V L+ +P + NVLL+C + IF I+GVQL+ G
Sbjct: 188 RIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWEG 230
Score = 89.4 bits (212), Expect = 9e-16
Identities = 62/204 (30%), Positives = 109/204 (53%), Gaps = 9/204 (4%)
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL 1590
++V K F I+ I +N L+M ++++ Q E + V++ N++F +F+ E LLKI A
Sbjct: 764 KLVDHKYFQQGILFAILINTLSMGIEYHNQPEELTVVVEISNIVFSAVFAVEMLLKIIAE 823
Query: 1591 R-YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYF--VSPTLLRVVRVAKVGRVLRLVKG 1647
+ Y +N+FD +VV+ S++ L S E+ + L V+R ++ R+L+LV+
Sbjct: 824 GPFGYISNGFNVFDGIVVVLSVVELCQSFAEERGSGGSGSSGLSVLRTFRLLRILKLVRF 883
Query: 1648 AKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF---MHVKDKGGLD---DVYN 1701
+R LF + ++ + LL L +FIF+I GM+ F GG D D N
Sbjct: 884 MPNLRRQLFVMLRTMDNVAIFFSLLVLFIFIFSILGMNLFGCKFCETMNGGSDVECDRKN 943
Query: 1702 FKTFVQSMILLFQMSTSAGWDGVL 1725
F + + +++ +FQ+ T W+ VL
Sbjct: 944 FDSLLWAIVTVFQILTQEDWNVVL 967
Score = 87.0 bits (206), Expect = 5e-15
Identities = 57/191 (29%), Positives = 103/191 (53%), Gaps = 19/191 (9%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEV-------- 171
AL L+ R + ++ +P F + IL+NCI + M P V+ V
Sbjct: 55 ALRYLEQSTRPRNWCLALITNPWFERISMMVILLNCITLGM-YQPCVDDQCVTNRCKILQ 113
Query: 172 ----IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVI---ALAYVTMGIDLGNL 224
I ++ E +K++A G I TYL D+WN LDF ++ +L Y + ++ NL
Sbjct: 114 MFDDIIFAFFSLEMTIKMVAMG-IYGKGTYLADSWNRLDFFIVLAGSLEYC-LNVENMNL 171
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
+A+RT RVLR L+ + +P ++ +V +++++ L +V++L F +F ++G+Q++ G+
Sbjct: 172 SAIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWEGI 231
Query: 285 LTQKC-VKVFP 294
L Q+C +K P
Sbjct: 232 LRQRCFLKALP 242
Score = 78.2 bits (184), Expect = 2e-12
Identities = 61/281 (21%), Positives = 134/281 (47%), Gaps = 36/281 (12%)
Query: 1211 TFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIK 1270
T KL+++ YF+ ++ IL+++L++ +E + P L ++ + +F+ +F +EML+K
Sbjct: 762 TKKLVDHKYFQQGILFAILINTLSMGIEYHNQPEE--LTVVVEISNIVFSAVFAVEMLLK 819
Query: 1271 WLALGFQKYFTNAWCWLDFIIVMVSLINFVAALC-----GAGGIQAFKTMRTLRALRPLR 1325
+A G Y +N + D I+V++S++ + G G +RT R LR L+
Sbjct: 820 IIAEGPFGYISNGFNVFDGIVVVLSVVELCQSFAEERGSGGSGSSGLSVLRTFRLLRILK 879
Query: 1326 AMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLS 1385
+ M +R + +++ + ++ + ++F IF+I+G+ LF K+ C MN
Sbjct: 880 LVRFMPNLRRQLFVMLRTMDNVAIFFSLLVLFIFIFSILGMNLFGCKF--CETMNG---G 934
Query: 1386 HEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQP 1445
++ D+ NFD + A + +FQ+ T + W ++ +
Sbjct: 935 SDVECDRK--------------NFDSLLWAIVTVFQILTQEDWNVVLFNG---------- 970
Query: 1446 IRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
+++T+ + LY NL + ++++ F+ ++ +
Sbjct: 971 MQKTSHWAALYFVALMTFGNYVLFNLLVAILVEGFSSERNE 1011
Score = 72.9 bits (171), Expect = 8e-11
Identities = 44/182 (24%), Positives = 92/182 (50%), Gaps = 18/182 (9%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM--PTTPT-------VESTE 170
+L++ N R + + F ++ I +NCI + M P P + S
Sbjct: 1438 SLYLFPQSNRFRVFCRWFVDQKWFDNVVLLFIGLNCITLAMERPNIPPDSRERLFLASAN 1497
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA---- 226
IFT ++ E VKV+A G + Y WN +D ++ ++ + +G+ L + ++
Sbjct: 1498 YIFTAVFAVEMFVKVVATGMLYGSDAYFTSGWNIMDGSLVVISIIDLGMSLLSSSSPRIF 1557
Query: 227 --LRTFRVLRALKTVAIV---PGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
LR FR+LR+L+ + ++ PGLK +V ++ S++ + +++++ +F ++G+Q++
Sbjct: 1558 GILRVFRLLRSLRPLRVINRAPGLKLVVQTLLSSLRPIGNIVLICCTFFVIFGILGVQLF 1617
Query: 282 MG 283
G
Sbjct: 1618 KG 1619
Score = 63.7 bits (148), Expect = 5e-08
Identities = 52/174 (29%), Positives = 80/174 (45%), Gaps = 19/174 (10%)
Query: 1524 RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQ-----QSETFSA-VLDYLNMIFIV 1577
RP+ ++T+ F+ I M+ I LN +T+ + YQ Q T +L + I
Sbjct: 64 RPRNWCLALITNPWFERISMMVILLNCITLGM--YQPCVDDQCVTNRCKILQMFDDIIFA 121
Query: 1578 IFSSECLLKIFALRYH----YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVV 1633
FS E +K+ A+ + Y + WN DF +V+ L L+ V L +
Sbjct: 122 FFSLEMTIKMVAMGIYGKGTYLADSWNRLDFFIVLAGSLEYCLN-------VENMNLSAI 174
Query: 1634 RVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
R +V R LR + +R L+ L +LP L N+ LL F V FIF I G+ +
Sbjct: 175 RTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLW 228
Score = 62.9 bits (146), Expect = 9e-08
Identities = 41/160 (25%), Positives = 80/160 (50%), Gaps = 22/160 (13%)
Query: 140 HPLFSLFIITTILVNCILMIMP-------TTPTVESTEVIFTGIYTFESAVKVMARGFIL 192
H F I+ IL+N + M + T VE + ++F+ ++ E +K++A G
Sbjct: 768 HKYFQQGILFAILINTLSMGIEYHNQPEELTVVVEISNIVFSAVFAVEMLLKIIAEG--- 824
Query: 193 QPFTYLRDAWNWLDFVVIALAYVTM-----------GIDLGNLAALRTFRVLRALKTVAI 241
PF Y+ + +N D +V+ L+ V + G L+ LRTFR+LR LK V
Sbjct: 825 -PFGYISNGFNVFDGIVVVLSVVELCQSFAEERGSGGSGSSGLSVLRTFRLLRILKLVRF 883
Query: 242 VPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+P L+ + ++ ++ N+ L + + +F+++G+ ++
Sbjct: 884 MPNLRRQLFVMLRTMDNVAIFFSLLVLFIFIFSILGMNLF 923
Score = 56.8 bits (131), Expect = 6e-06
Identities = 29/93 (31%), Positives = 51/93 (54%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L++ LR+ KL + P L + +M RTM + +L + IFIF+++GM LFG +
Sbjct: 869 LRTFRLLRILKLVRFMPNLRRQLFVMLRTMDNVAIFFSLLVLFIFIFSILGMNLFGCKFC 928
Query: 887 DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE 919
+ ++ D + R NF + + + VF++L E
Sbjct: 929 ETMNGGSDVECDRKNFDSLLWAIVTVFQILTQE 961
Score = 53.2 bits (122), Expect = 7e-05
Identities = 32/144 (22%), Positives = 72/144 (50%), Gaps = 14/144 (9%)
Query: 148 ITTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDF 207
+ T+ + +M T ++ FT ++ ES +K++A G L YL+D WN LD
Sbjct: 1791 VVTMAMEFYMMPKALTYALKIFNYFFTAVFILESFMKLLALGLHL----YLKDKWNQLDI 1846
Query: 208 VVIALAYV----------TMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVK 257
++ L+ V + I+ + +R R+ R LK + + G++ ++ V++++
Sbjct: 1847 GIVILSVVGIVLEELESKIIPINPTIIRVMRVLRIARVLKLLKMAKGIRALLDTVMQALP 1906
Query: 258 NLRDVIILTMFSLSVFALMGLQIY 281
+ ++ +L +FA +G++++
Sbjct: 1907 QVGNLGLLFFLLFFIFAALGVELF 1930
Score = 48.4 bits (110), Expect = 0.002
Identities = 30/97 (30%), Positives = 53/97 (54%), Gaps = 4/97 (4%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
RV KL K + L+ + + + +GNL + ++ FIFA +G++LFG+ ++ D P
Sbjct: 1883 RVLKLLKMAKGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELFGR--LECSDEMP 1940
Query: 894 -DGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
G +F++F +F+ +FRV G+ W M D +
Sbjct: 1941 CQGLGEHAHFSNFGMAFLTLFRVATGDNWNGIMKDTL 1977
Score = 46.0 bits (104), Expect = 0.011
Identities = 23/79 (29%), Positives = 44/79 (55%), Gaps = 11/79 (13%)
Query: 340 YVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ-----------LFFVVII 388
Y +G G NP G SFD G A+++ F +++ + W ++ ++FV++I
Sbjct: 312 YTECKGQGNNPFQGTISFDNIGLAWVAIFLVISLEGWTDIMYYVQDAHSFWDWIYFVLLI 371
Query: 389 FLGSFYLVNLILAIVAMSY 407
+GSF+++NL L ++A +
Sbjct: 372 VIGSFFMINLCLVVIATQF 390
Score = 37.5 bits (83), Expect = 3.7
Identities = 19/77 (24%), Positives = 42/77 (54%), Gaps = 3/77 (3%)
Query: 805 IVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTF 864
++ +L L+ NM+ A+++ LR + P++ +L+ ++ T+ LGN+
Sbjct: 155 VLAGSLEYCLNVENMNLS---AIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLL 211
Query: 865 VLCIIIFIFAVMGMQLF 881
+ + FIF ++G+QL+
Sbjct: 212 LCFFVFFIFGIVGVQLW 228
Score = 36.3 bits (80), Expect = 8.5
Identities = 14/49 (28%), Positives = 27/49 (55%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
LR ++ P L L++ + ++ +GN+ + C IF ++G+QLF
Sbjct: 1569 LRPLRVINRAPGLKLVVQTLLSSLRPIGNIVLICCTFFVIFGILGVQLF 1617
>UniRef50_UPI000065EC32 Cluster: Voltage-dependent R-type calcium
channel subunit alpha-1E (Voltage- gated calcium channel
subunit alpha Cav2.3) (Calcium channel, L type, alpha-1
polypeptide, isoform 6) (Brain calcium channel II)
(BII).; n=2; Clupeocephala|Rep: Voltage-dependent R-type
calcium channel subunit alpha-1E (Voltage- gated calcium
channel subunit alpha Cav2.3) (Calcium channel, L type,
alpha-1 polypeptide, isoform 6) (Brain calcium channel
II) (BII). - Takifugu rubripes
Length = 2232
Score = 297 bits (728), Expect = 3e-78
Identities = 212/737 (28%), Positives = 362/737 (49%), Gaps = 66/737 (8%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
++ YFE ++ +I+ SS+ALA ED + +L Y D +FT +F EM+IK +
Sbjct: 1059 IVTMRYFEMTILLVIVASSIALAAEDPVCTNSD-RNKVLRYFDYVFTGVFTFEMIIKMID 1117
Query: 1274 LGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSR 1329
G YF + W LDFI+V+ +LI F I+ K++R LR LRPL+ + R
Sbjct: 1118 QGLILHDGSYFRDMWNLLDFIVVVGALIAFALTNNKGRDIKTIKSLRVLRVLRPLKTIKR 1177
Query: 1330 MQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD--MNHTTLSHE 1387
+ ++ V + +V ++ ++FN+L+V +F IFA++ VQLF GK+F C D M
Sbjct: 1178 LPKLKAVFDCVVTSLKNVFNILIVYQLFMFIFAVIAVQLFKGKFFYCTDGSMKSEKECQG 1237
Query: 1388 IIPD--KNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQP 1445
D ++ ++ W ++D+VG A L LF ++T +GW Q++ + D E P
Sbjct: 1238 FYIDYTRDKKEVKRREWRRHEFHYDNVGWALLTLFTISTGEGWPQVLQHSTDVTEEDMGP 1297
Query: 1446 IRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNA 1505
R + M + +N+F+ +II F EQ K E + ++++ +
Sbjct: 1298 SRGNRMEMSAFYVVYFVVFPFFFVNIFVALIIITFQEQGDKM--IHECSLEKNERACIDF 1355
Query: 1506 MKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFS 1565
+ +K + +P+ R Q ++ V F+ +++ I LN + + + +Y +
Sbjct: 1356 --TISAKPMTRYMPQNRQTLQYRLWHFVASPSFEYTVLVMIALNTVVLMMKYYSAPTAYD 1413
Query: 1566 AVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFV 1625
VL +LN F V+FS EC+LKI A +YF + WN+FDF+ V+ SI S ++ D+ +
Sbjct: 1414 TVLKHLNTAFTVLFSLECILKILAFGLNYFRDTWNIFDFITVLGSI-SEIIVDLQSVNTI 1472
Query: 1626 SPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGM- 1684
+ + L++ R A R+++L++ IR LL+ S AL +CLL+ ++ FIFAI GM
Sbjct: 1473 NMSFLKLFRTA---RLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIFAIIGMQ 1529
Query: 1685 ---------------------SFFMHVKDKGGLDDV------YNFKTFVQSMILLFQMST 1717
+ F+ V LDD NFKTF +++LLF+ +T
Sbjct: 1530 VSTKPGGDEWSSEKGSHLREPACFLQVFGNIKLDDESHINQHNNFKTFFSALMLLFRSAT 1589
Query: 1718 SAGWDGVLDGIINEEECDLPDNERG----SP---GNCGSATIGITYLLSYLVISFLIVIN 1770
W ++ ++ +EC+ PD SP G CG+ Y +S++ +S +++N
Sbjct: 1590 GESWQEIMLSCLSGQECE-PDPSIAPLTLSPDHEGGCGT-DFAYCYFVSFIFLSSFLMLN 1647
Query: 1771 MYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPL 1830
+++AVI++N+ T D L D + IW +D I Y + + L + PPL
Sbjct: 1648 LFVAVIMDNFEYLTRD-SSILGPHHLDEFVRIWGEYDRLACGRIHYTAMYEMLTHMSPPL 1706
Query: 1831 QIHK--PNK--YK-IISMDIPICRGDMMFCVDILDALTK---DFFARKGNPI-EETGDLE 1881
+ K P K YK ++ M++P+ + L +L + D +G P+ E G+
Sbjct: 1707 GLGKKCPAKIAYKRLVLMNMPVDEDMTVHFTSTLMSLIRTALDIKIARGQPLFEMCGEDR 1766
Query: 1882 VGRPEEAGYEPVSSTLW 1898
+G E E S +W
Sbjct: 1767 IGLDSELQKE--ISIIW 1781
Score = 118 bits (283), Expect = 2e-24
Identities = 84/285 (29%), Positives = 145/285 (50%), Gaps = 50/285 (17%)
Query: 147 IITTILVNCILMIM----------PTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFT 196
I+ TI NC+++ + P +E TE F GI+ FE+ +K++A GF+ +
Sbjct: 2 ILATITANCVVLALEQHLPGEDKTPMAKRLEKTEPYFIGIFCFEAGIKLVALGFVFHKGS 61
Query: 197 YLRDAWNWLDFVVI-----ALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGA 251
YLR+ WN +DF+V+ A A M I + +L LR RVLR LK V+ +P L+ ++ +
Sbjct: 62 YLRNGWNVMDFIVVLSGILATAGAHMNIPV-DLRTLRAVRVLRPLKLVSGIPSLQIVLKS 120
Query: 252 VIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFC 311
+++++ L + +L F++ +FA++GL+ Y G L Q C+ P D N T ++ E
Sbjct: 121 IMKAMIPLLQIGLLLFFAILMFAIIGLEFYSGKLHQTCL---PSDDIQDNETVDSSE--- 174
Query: 312 QNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLM 371
+ G +C Y C + PN G T FD +A L+ F+ +
Sbjct: 175 ---------------LAFACGVRKCPEKYECRDTW-IGPNDGITQFDNILFAVLTVFQCI 218
Query: 372 TQDYWEN-LYQ-----------LFFVVIIFLGSFYLVNLILAIVA 404
T + W LY ++F+ +I +GSF+++NL+L +++
Sbjct: 219 TMEGWTAVLYNTNDALGTTWNWMYFIPLIIIGSFFVLNLVLGVLS 263
Score = 108 bits (259), Expect = 2e-21
Identities = 58/181 (32%), Positives = 102/181 (56%), Gaps = 14/181 (7%)
Query: 117 ATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM--PTTPTVESTEV--- 171
A ++++I NPIRR+ YI+ F + I+ I+ + I + P + +V
Sbjct: 1039 APDSMFIFKASNPIRRICHYIVTMRYFEMTILLVIVASSIALAAEDPVCTNSDRNKVLRY 1098
Query: 172 ---IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM------GIDLG 222
+FTG++TFE +K++ +G IL +Y RD WN LDF+V+ A + G D+
Sbjct: 1099 FDYVFTGVFTFEMIIKMIDQGLILHDGSYFRDMWNLLDFIVVVGALIAFALTNNKGRDIK 1158
Query: 223 NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYM 282
+ +LR RVLR LKT+ +P LK + V+ S+KN+ +++I+ + +FA++ +Q++
Sbjct: 1159 TIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVTSLKNVFNILIVYQLFMFIFAVIAVQLFK 1218
Query: 283 G 283
G
Sbjct: 1219 G 1219
Score = 93.5 bits (222), Expect = 5e-17
Identities = 75/310 (24%), Positives = 142/310 (45%), Gaps = 35/310 (11%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
LR+ ++++ F V++++ L+++ +A+ VH L LYY + +F +F E
Sbjct: 423 LRISIRRMVKTDTFYLMVLSLVALNTICVAI--VHHNQPGWLTIFLYYAEFVFLGLFLAE 480
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
M +K LGF+ YF +++ D +++ S+ V G +R LR LR +
Sbjct: 481 MFLKIYGLGFRLYFHSSFNCFDCGVIVGSIFEVVWGFFRPGISFGISVLRALRLLRIFKI 540
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH 1386
+R +V +L+ ++ SI ++L + +F ++FA++G+QLF G++
Sbjct: 541 TKYWASLRNLVVSLMSSMKSIISLLFLLFLFTVVFALLGMQLFGGRFI------------ 588
Query: 1387 EIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPI 1446
E+YT P NFD A + +FQ+ T + W ++M D I S Q
Sbjct: 589 ----------FEDYT----PTNFDTFPAAIMTVFQILTGEDWNEVMYDGIRS-----QGG 629
Query: 1447 RETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNF-NEQK-KKAGGSLEMFMTEDQKKYYN 1504
+ ++ +Y LN+F+ + +DN N Q+ K E F + + +
Sbjct: 630 VQYGMWSSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEEEEEEFFNQRYARGRD 689
Query: 1505 AMKKMGSKKP 1514
+ G ++P
Sbjct: 690 GLISDGRRRP 699
Score = 86.6 bits (205), Expect = 6e-15
Identities = 71/290 (24%), Positives = 129/290 (44%), Gaps = 19/290 (6%)
Query: 1206 TLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFI 1265
TL+ + + + + FE V+ MI L+++ L ++ P +L +++ FTV+F +
Sbjct: 1372 TLQYRLWHFVASPSFEYTVLVMIALNTVVLMMKYYSAP--TAYDTVLKHLNTAFTVLFSL 1429
Query: 1266 EMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLR 1325
E ++K LA G YF + W DFI V+ S+ + L I ++ R R ++
Sbjct: 1430 ECILKILAFGLN-YFRDTWNIFDFITVLGSISEIIVDLQSVNTIN-MSFLKLFRTARLIK 1487
Query: 1326 AMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF---AGKYFKCVDMNHT 1382
+ + +R+++ VQ+ ++ V L+ + + IFAI+G+Q+ G + +H
Sbjct: 1488 LLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIFAIIGMQVSTKPGGDEWSSEKGSHL 1547
Query: 1383 TLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVG 1442
+ L++ + N NF A + LF+ AT + W +IM + +E
Sbjct: 1548 REPACFLQVFGNIKLDDESHINQHNNFKTFFSALMLLFRSATGESWQEIMLSCLSGQECE 1607
Query: 1443 RQP-IRETNI-----------YMYLYXXXXXXXXXXXTLNLFIGVIIDNF 1480
P I + + Y Y LNLF+ VI+DNF
Sbjct: 1608 PDPSIAPLTLSPDHEGGCGTDFAYCYFVSFIFLSSFLMLNLFVAVIMDNF 1657
Score = 85.8 bits (203), Expect = 1e-14
Identities = 66/293 (22%), Positives = 135/293 (46%), Gaps = 23/293 (7%)
Query: 1508 KMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAV 1567
+ G + P + R + + +V F ++++ + LN + + + H+ Q +
Sbjct: 406 RSGRRGPAAYLRRKERMLRISIRRMVKTDTFYLMVLSLVALNTICVAIVHHNQPGWLTIF 465
Query: 1568 LDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVS 1626
L Y +F+ +F +E LKI+ L + YF +N FD V++ SI +V
Sbjct: 466 LYYAEFVFLGLFLAEMFLKIYGLGFRLYFHSSFNCFDCGVIVGSIFEVVWGFFRPGISFG 525
Query: 1627 PTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSF 1686
++LR +R+ R+ ++ K +R L+ +L S+ ++ ++ LLFL +FA+ GM
Sbjct: 526 ISVLRALRLL---RIFKITKYWASLRNLVVSLMSSMKSIISLLFLLFLFTVVFALLGMQL 582
Query: 1687 FMHVKDKGGLDDV--YNFKTFVQSMILLFQMSTSAGWDGVL-DGIINEEECDLPDNERGS 1743
F + +D NF TF +++ +FQ+ T W+ V+ DGI S
Sbjct: 583 F---GGRFIFEDYTPTNFDTFPAAIMTVFQILTGEDWNEVMYDGI-------------RS 626
Query: 1744 PGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDY 1796
G Y + + ++N+++A+ ++N + A E ++ ++++
Sbjct: 627 QGGVQYGMWSSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEEEEEEF 679
Score = 79.8 bits (188), Expect = 7e-13
Identities = 72/284 (25%), Positives = 135/284 (47%), Gaps = 34/284 (11%)
Query: 1224 VITMILLSSLALALEDVHLP--HRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQ---- 1277
++ I + + LALE HLP + + L + F IF E IK +ALGF
Sbjct: 2 ILATITANCVVLALEQ-HLPGEDKTPMAKRLEKTEPYFIGIFCFEAGIKLVALGFVFHKG 60
Query: 1278 KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVV 1337
Y N W +DFI+V+ ++ A +T+R +R LRPL+ +S + +++V+
Sbjct: 61 SYLRNGWNVMDFIVVLSGILATAGAHMNIP--VDLRTLRAVRVLRPLKLVSGIPSLQIVL 118
Query: 1338 NALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK-C-----VDMNHTTLSHEI--- 1388
++++A+ + + L+ L+FAI+G++ ++GK + C + N T S E+
Sbjct: 119 KSIMKAMIPLLQIGLLLFFAILMFAIIGLEFYSGKLHQTCLPSDDIQDNETVDSSELAFA 178
Query: 1389 -----IPDKNACTLENYTWENSPM-NFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVG 1442
P+K C + + N + FD++ A L +FQ T +GW ++ + D+ +G
Sbjct: 179 CGVRKCPEKYECR-DTWIGPNDGITQFDNILFAVLTVFQCITMEGWTAVLYNTNDA--LG 235
Query: 1443 RQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
+ ++Y LNL +GV+ F +++++
Sbjct: 236 -------TTWNWMYFIPLIIIGSFFVLNLVLGVLSGEFAKERER 272
Score = 64.9 bits (151), Expect = 2e-08
Identities = 39/102 (38%), Positives = 63/102 (61%), Gaps = 10/102 (9%)
Query: 827 LKSGNYLRVFKLAKSWPTL-NLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY 885
L++ LR+FK+ K W +L NL++S+M +M ++ +L F+L + +FA++GMQLFG +
Sbjct: 529 LRALRLLRIFKITKYWASLRNLVVSLMS-SMKSIISLLFLLFLFTVVFALLGMQLFGGRF 587
Query: 886 VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWD 926
+ + D P NF F + M VF++L GE W E M+D
Sbjct: 588 I-FEDYTPT------NFDTFPAAIMTVFQILTGEDWNEVMYD 622
Score = 62.1 bits (144), Expect = 1e-07
Identities = 45/155 (29%), Positives = 77/155 (49%), Gaps = 13/155 (8%)
Query: 1541 IIMLFIGLNMLTMTLDHYQQSETFSAV---LDYLNMIFIVIFSSECLLKIFALRY----- 1592
+I+ I N + + L+ + E + + L+ FI IF E +K+ AL +
Sbjct: 1 MILATITANCVVLALEQHLPGEDKTPMAKRLEKTEPYFIGIFCFEAGIKLVALGFVFHKG 60
Query: 1593 HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIR 1652
Y WN+ DF+VV+ IL+ + + P LR +R +V R L+LV G ++
Sbjct: 61 SYLRNGWNVMDFIVVLSGILATAGA-----HMNIPVDLRTLRAVRVLRPLKLVSGIPSLQ 115
Query: 1653 TLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+L ++ ++ L I LLLF + +FAI G+ F+
Sbjct: 116 IVLKSIMKAMIPLLQIGLLLFFAILMFAIIGLEFY 150
Score = 57.6 bits (133), Expect = 3e-06
Identities = 38/157 (24%), Positives = 76/157 (48%), Gaps = 17/157 (10%)
Query: 136 YILVHPLFSLFIITTILVNCILMIMP--TTPTVEST-----EVIFTGIYTFESAVKVMAR 188
+ + P F ++ I +N ++++M + PT T FT +++ E +K++A
Sbjct: 1379 HFVASPSFEYTVLVMIALNTVVLMMKYYSAPTAYDTVLKHLNTAFTVLFSLECILKILAF 1438
Query: 189 GFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLG-----NLAALRTFRVLRALKTVAIVP 243
G Y RD WN DF+ + + + +DL N++ L+ FR R +K +
Sbjct: 1439 GL-----NYFRDTWNIFDFITVLGSISEIIVDLQSVNTINMSFLKLFRTARLIKLLRQGY 1493
Query: 244 GLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
++ ++ ++S K L V +L +FA++G+Q+
Sbjct: 1494 TIRILLWTFVQSFKALPYVCLLIAMLFFIFAIIGMQV 1530
Score = 51.2 bits (117), Expect = 3e-04
Identities = 41/151 (27%), Positives = 70/151 (46%), Gaps = 14/151 (9%)
Query: 142 LFSLFIITTILVNCILMIMPTTPTV--ESTEVIFTGIYTFESAVKVMARGFILQPFTYLR 199
+ SL + TI V + P T+ E +F G++ E +K+ GF L Y
Sbjct: 440 VLSLVALNTICVAIVHHNQPGWLTIFLYYAEFVFLGLFLAEMFLKIYGLGFRL----YFH 495
Query: 200 DAWNWLDFVVIA-------LAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAV 252
++N D VI + GI G ++ LR R+LR K L+ +V ++
Sbjct: 496 SSFNCFDCGVIVGSIFEVVWGFFRPGISFG-ISVLRALRLLRIFKITKYWASLRNLVVSL 554
Query: 253 IESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
+ S+K++ ++ L VFAL+G+Q++ G
Sbjct: 555 MSSMKSIISLLFLLFLFTVVFALLGMQLFGG 585
>UniRef50_Q86G45 Cluster: High voltage activated calcium channel
alpha-1 subunit; n=7; Bilateria|Rep: High voltage
activated calcium channel alpha-1 subunit -
Caenorhabditis elegans
Length = 2027
Score = 296 bits (726), Expect = 5e-78
Identities = 212/750 (28%), Positives = 362/750 (48%), Gaps = 42/750 (5%)
Query: 1160 GKTDIKVGADEDVVDDTPADCCPEQCYQKFPFLAGDDDSPFWQG-WGTLRLKTFKLIENT 1218
GKT + A +DD +C E+ P S F+ R+ ++
Sbjct: 795 GKTAGDMCAVARAMDDLDEECEEEESPFGGPKPMVPYSSMFFLSPTNPFRVLIHSIVCTK 854
Query: 1219 YFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQ- 1277
YFE V+T+I LSS++LA ED P +L YMD FT +F EML+K + G
Sbjct: 855 YFEMMVMTVICLSSVSLAAEDPVDEENP-RNKVLQYMDYCFTGVFACEMLLKLIDQGILL 913
Query: 1278 ---KYFTNAWCWLDFIIVMVSLINF-VAALCGAGG--IQAFKTMRTLRALRPLRAMSRMQ 1331
Y + W LD I+V +L F A G+ G + K++R LR LRPL+ + R+
Sbjct: 914 HPGSYCRDFWNILDGIVVTCALFAFGFAGTEGSAGKNLNTIKSLRVLRVLRPLKTIKRIP 973
Query: 1332 GMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMN----HTTLSHE 1387
++ V + +V ++ ++FN+L+V +F IFA++ VQLF GK+F C D N +T
Sbjct: 974 KLKAVFDCVVNSLKNVFNILIVYFLFQFIFAVIAVQLFNGKFFFCTDKNRKFANTCHGQF 1033
Query: 1388 IIPD--KNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQP 1445
+ D + +E W P N+D+ A L LF V T +GW I +++D+ + P
Sbjct: 1034 FVYDNQNDPPRVEQREWRLRPFNYDNTINAMLTLFVVTTGEGWPGIRQNSMDTTFEDQGP 1093
Query: 1446 IRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNA 1505
+ + L+ +N+F+ +II F EQ G E+ + K
Sbjct: 1094 SPFFRVEVALFYVMFFIVFPFFFVNIFVALIIITFQEQ-----GEAELSEGDLDKNQKQC 1148
Query: 1506 MKKMGSKKPLKA-IPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETF 1564
+ + +P +P + + ++ +VT F+ IM I N L + + +Y +
Sbjct: 1149 IDFALNARPRSLFMPEDKNSTKYRIWRLVTSPPFEYFIMTMICCNTLILMMKYYNNPLFY 1208
Query: 1565 SAVLDYLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSLVLSDIIEKY 1623
+L N +F+ E +LKI A +YF + WN FDFV V+ SI ++++ +
Sbjct: 1209 EEILRLFNTALTAVFTVESILKILAFGVRNYFRDGWNRFDFVTVVGSITDALVTE-FGGH 1267
Query: 1624 FVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFG 1683
FVS LR+ R A R++RL++ IR LL+ S AL +CLL+ ++ FI+AI G
Sbjct: 1268 FVSLGFLRLFRAA---RLIRLLQQGYTIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVG 1324
Query: 1684 MSFFMHV--KDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDN-- 1739
M F ++ ++ NF++F ++ILLF+ +T GW ++ + ++C +
Sbjct: 1325 MQVFGNIWLNAATEINRHNNFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAE 1384
Query: 1740 ---ERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDY 1796
E+G CGS + Y S++ +S +++N+++AVI++N+ T D L
Sbjct: 1385 INFEKGQ--TCGS-NVSYAYFTSFVFLSSFLMLNLFVAVIMDNFDYLTRD-SSILGPHHL 1440
Query: 1797 DMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHKPNKYK-----IISMDIPICRGD 1851
D + +W +DP + I Y ++ + L ++ PP+ K Y+ +I M++P+
Sbjct: 1441 DEFIRVWADYDPAATGRIHYSEMYEMLRIMAPPVGFGKKCPYRLAYKHLIRMNMPVAEDG 1500
Query: 1852 MMFCVDILDALTKDFFARKGNPIEETGDLE 1881
+ L AL ++ + K P+EE + +
Sbjct: 1501 TVHFTTTLFALIRESLSIKMRPVEEMDEAD 1530
Score = 135 bits (326), Expect = 1e-29
Identities = 98/321 (30%), Positives = 163/321 (50%), Gaps = 54/321 (16%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT----------TPTVES 168
++L+I N IRR A I+ F FI+ TI+ NC+++ M + +E
Sbjct: 86 SSLFIFAEDNIIRRNAKAIIEWGPFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLER 145
Query: 169 TEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM----------- 217
TE F GI+ E +KV+A GF L +YLR WN +DF+V+ VTM
Sbjct: 146 TEPYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTAN 205
Query: 218 -GIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALM 276
+D +L LR RVLR LK V+ +P L+ ++ +++ ++ L + +L +F++ +FA++
Sbjct: 206 QPVDSVDLRTLRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVLFAIIIFAII 265
Query: 277 GLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQC 336
GL+ Y G C + E G N+++ C N+T+ P+ G C
Sbjct: 266 GLEFYSGAFHSAC---YNERGEIENVSERPMP--CTNKTS--------PM-----GVYNC 307
Query: 337 E-PGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ------------LF 383
+ G CLQ + PNYG TSFD G+A ++ F+ +T + W + +
Sbjct: 308 DVKGTTCLQKW-IGPNYGITSFDNIGFAMITVFQCITMEGWTTVMYYTNDSLGSTYNWAY 366
Query: 384 FVVIIFLGSFYLVNLILAIVA 404
F+ +I LGSF+++NL+L +++
Sbjct: 367 FIPLIVLGSFFMLNLVLGVLS 387
Score = 93.1 bits (221), Expect = 7e-17
Identities = 77/282 (27%), Positives = 133/282 (47%), Gaps = 33/282 (11%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
LR++ +++ F +VIT++ L++ +A E H D L Y + +F IF +E
Sbjct: 512 LRIQIRIMVKTQIFYWSVITLVFLNTCCVASE--HYGQPQWFTDFLKYAEFVFLGIFVVE 569
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
ML+K A+G + YF + + D ++++ S + A GG MR LR LR +
Sbjct: 570 MLLKLFAMGSRTYFASKFNRFDCVVIVGSAAEVIWAEV-YGGSFGISVMRALRLLRIFKL 628
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH 1386
S +R +V +L+ ++ SI ++L + +F LIFA++G+QLF G++
Sbjct: 629 TSYWVSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFGGRF------------- 675
Query: 1387 EIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPI 1446
N T+ YT +FD A + +FQ+ T + W ++M AI+S + I
Sbjct: 676 ------NFPTMHPYT------HFDTFPVALITVFQILTGEDWNEVMYLAIES----QGGI 719
Query: 1447 RETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNF-NEQKKKA 1487
+Y LN+F+ + +DN N Q+ A
Sbjct: 720 YSGGWPYSIYFIVLVLFGNYTLLNVFLAIAVDNLANAQELTA 761
Score = 91.9 bits (218), Expect = 2e-16
Identities = 50/182 (27%), Positives = 95/182 (52%), Gaps = 17/182 (9%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM--------PTTPTVESTE 170
++++ L P NP R + I+ F + ++T I ++ + + P ++ +
Sbjct: 832 SSMFFLSPTNPFRVLIHSIVCTKYFEMMVMTVICLSSVSLAAEDPVDEENPRNKVLQYMD 891
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI---------DL 221
FTG++ E +K++ +G +L P +Y RD WN LD +V+ A G +L
Sbjct: 892 YCFTGVFACEMLLKLIDQGILLHPGSYCRDFWNILDGIVVTCALFAFGFAGTEGSAGKNL 951
Query: 222 GNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+ +LR RVLR LKT+ +P LK + V+ S+KN+ +++I+ +FA++ +Q++
Sbjct: 952 NTIKSLRVLRVLRPLKTIKRIPKLKAVFDCVVNSLKNVFNILIVYFLFQFIFAVIAVQLF 1011
Query: 282 MG 283
G
Sbjct: 1012 NG 1013
Score = 89.4 bits (212), Expect = 9e-16
Identities = 55/195 (28%), Positives = 101/195 (51%), Gaps = 5/195 (2%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR 1591
+V + F ++ + LN + +HY Q + F+ L Y +F+ IF E LLK+FA+
Sbjct: 519 MVKTQIFYWSVITLVFLNTCCVASEHYGQPQWFTDFLKYAEFVFLGIFVVEMLLKLFAMG 578
Query: 1592 YH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
YF +N FD VV++ S ++ +++ F + V+R ++ R+ +L
Sbjct: 579 SRTYFASKFNRFDCVVIVGSAAEVIWAEVYGGSFG----ISVMRALRLLRIFKLTSYWVS 634
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMI 1710
+R L+ +L S+ ++ ++ LLFL + IFA+ GM F + + +F TF ++I
Sbjct: 635 LRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFGGRFNFPTMHPYTHFDTFPVALI 694
Query: 1711 LLFQMSTSAGWDGVL 1725
+FQ+ T W+ V+
Sbjct: 695 TVFQILTGEDWNEVM 709
Score = 80.6 bits (190), Expect = 4e-13
Identities = 80/325 (24%), Positives = 152/325 (46%), Gaps = 40/325 (12%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPH--RPILQDILYYMDRIFTVIFF 1264
+R +IE FE ++ I+ + + L++E HLP + L + L + F IF
Sbjct: 97 IRRNAKAIIEWGPFEYFILLTIIGNCVVLSMEQ-HLPKNDKKALSEWLERTEPYFMGIFC 155
Query: 1265 IEMLIKWLALGFQ----KYFTNAWCWLDFIIVM---VSLINFVAALCGAGG-IQA--FKT 1314
+E ++K +A GF Y + W +DFI+V+ V+++ F A A + + +T
Sbjct: 156 LECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTANQPVDSVDLRT 215
Query: 1315 MRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYF 1374
+R +R LRPL+ +S + ++VV+ +++ A+ + + L+ L +IFAI+G++ ++G +
Sbjct: 216 LRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVLFAIIIFAIIGLEFYSGAFH 275
Query: 1375 K-CVDMNH--TTLSHEIIPDKNA--------CTLENYT----W---ENSPMNFDHVGKAY 1416
C + +S +P N C ++ T W +FD++G A
Sbjct: 276 SACYNERGEIENVSERPMPCTNKTSPMGVYNCDVKGTTCLQKWIGPNYGITSFDNIGFAM 335
Query: 1417 LCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVI 1476
+ +FQ T +GW +M DS +G + Y + Y LNL +GV+
Sbjct: 336 ITVFQCITMEGWTTVMYYTNDS--LG-------STYNWAYFIPLIVLGSFFMLNLVLGVL 386
Query: 1477 IDNFNEQKKKAGGSLEMFMTEDQKK 1501
F +++++ E Q++
Sbjct: 387 SGEFAKERERVENRREFLKLRRQQQ 411
Score = 58.0 bits (134), Expect = 2e-06
Identities = 35/94 (37%), Positives = 54/94 (57%), Gaps = 7/94 (7%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LR+FKL W +L L+ + +M ++ +L F+L + I IFA++GMQLFG + F
Sbjct: 623 LRIFKLTSYWVSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFGGRF-----NF 677
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMW 925
P P +F F + + VF++L GE W E M+
Sbjct: 678 PTMH-PYTHFDTFPVALITVFQILTGEDWNEVMY 710
Score = 56.0 bits (129), Expect = 1e-05
Identities = 61/247 (24%), Positives = 104/247 (42%), Gaps = 20/247 (8%)
Query: 137 ILVHPLFSLFIITTILVNCILMIMP--TTPTV-ESTEVIF----TGIYTFESAVKVMARG 189
++ P F FI+T I N ++++M P E +F T ++T ES +K++A G
Sbjct: 1176 LVTSPPFEYFIMTMICCNTLILMMKYYNNPLFYEEILRLFNTALTAVFTVESILKILAFG 1235
Query: 190 FILQPFTYLRDAWNWLDFVV----IALAYVT-MGIDLGNLAALRTFRVLRALKTVAIVPG 244
Y RD WN DFV I A VT G +L LR FR R ++ +
Sbjct: 1236 VR----NYFRDGWNRFDFVTVVGSITDALVTEFGGHFVSLGFLRLFRAARLIRLLQQGYT 1291
Query: 245 LKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTD 304
++ ++ ++S K L V +L ++A++G+Q++ + ++ +
Sbjct: 1292 IRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWLNAATEINRHNNFQSFFNA 1351
Query: 305 ENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAF 364
C W + + AG E + Q G N +Y Y F +F F
Sbjct: 1352 VILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAY--FTSF--VF 1407
Query: 365 LSAFRLM 371
LS+F ++
Sbjct: 1408 LSSFLML 1414
Score = 54.4 bits (125), Expect = 3e-05
Identities = 44/164 (26%), Positives = 81/164 (49%), Gaps = 17/164 (10%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMI---FIVIFSSECLLKIFALRY-- 1592
F+ I+L I N + ++++ + A+ ++L F+ IF EC+LK+ A +
Sbjct: 110 FEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTEPYFMGIFCLECVLKVIAFGFAL 169
Query: 1593 ---HYFVEPWNLFDFVVVMFSILSLV-LSDIIE--KYFVSPTLLRVVRVAKVGRVLRLVK 1646
Y WN+ DF+VV+ +++++ S + V LR +R +V R L+LV
Sbjct: 170 HKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTANQPVDSVDLRTLRAVRVLRPLKLVS 229
Query: 1647 GAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIF---GMSFF 1687
G ++ +L ++ ++ L I LL V+F IF G+ F+
Sbjct: 230 GIPSLQVVLKSILCAMAPLLQIGLL---VLFAIIIFAIIGLEFY 270
Score = 51.2 bits (117), Expect = 3e-04
Identities = 44/165 (26%), Positives = 81/165 (49%), Gaps = 17/165 (10%)
Query: 132 RVAIYILVHP-LFSLFIITTILVN--CILMI---MPT--TPTVESTEVIFTGIYTFESAV 183
R+ I I+V +F +IT + +N C+ P T ++ E +F GI+ E +
Sbjct: 513 RIQIRIMVKTQIFYWSVITLVFLNTCCVASEHYGQPQWFTDFLKYAEFVFLGIFVVEMLL 572
Query: 184 KVMARGFILQPFTYLRDAWNWLDFVVI--ALAYVTMGIDLGN---LAALRTFRVLRALKT 238
K+ A G TY +N D VVI + A V G ++ +R R+LR K
Sbjct: 573 KLFAMG----SRTYFASKFNRFDCVVIVGSAAEVIWAEVYGGSFGISVMRALRLLRIFKL 628
Query: 239 VAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
+ L+ +V +++ S++++ ++ L + +FAL+G+Q++ G
Sbjct: 629 TSYWVSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFGG 673
Score = 40.7 bits (91), Expect = 0.40
Identities = 23/92 (25%), Positives = 50/92 (54%), Gaps = 5/92 (5%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
R+ +L + T+ +L+ ++ AL + ++ ++ FI+A++GMQ+FG +++
Sbjct: 1281 RLIRLLQQGYTIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWLNAATEIN 1340
Query: 894 DGDLPRWNFTDFMHSFMIVFRVLCGE-WIESM 924
+ NF F ++ +++FR GE W + M
Sbjct: 1341 RHN----NFQSFFNAVILLFRCATGEGWQDIM 1368
>UniRef50_Q9W433 Cluster: CG15899-PB; n=16; Eumetazoa|Rep: CG15899-PB
- Drosophila melanogaster (Fruit fly)
Length = 2893
Score = 295 bits (723), Expect = 1e-77
Identities = 171/595 (28%), Positives = 315/595 (52%), Gaps = 29/595 (4%)
Query: 1215 IENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLAL 1274
+ +F+ V+ I L+ + LA+E ++P + L + +FTV+F +EM IK +A
Sbjct: 1847 VNQKWFDNVVLLFIALNCITLAMERPNIPPSSTERLFLATANYVFTVVFTVEMFIKVVAT 1906
Query: 1275 GF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAF---KTMRTLRALRPLRAM 1327
G YFT+ W +D +V +S+I+ + +L + F + R LR+LRPLR +
Sbjct: 1907 GMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSLISESSPRIFGILRVFRLLRSLRPLRVI 1966
Query: 1328 SRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHE 1387
+R G+++VV L+ ++ I N++L+C F++IF I+GVQLF G ++ C N +
Sbjct: 1967 NRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGTFYYCEGEN-----IK 2021
Query: 1388 IIPDKNAC-TLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPI 1446
+ + + C + W N NFD +GKA + LF +++ GW+ IM +D+ V +QPI
Sbjct: 2022 GVRNADECRRIPGNVWTNRKYNFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQPI 2081
Query: 1447 RETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAM 1506
N + LY LN+F+GV+++NF+ +++ ++ +
Sbjct: 2082 VNYNEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCREEQEKEEKIRRAAKRALQMEKK 2141
Query: 1507 KKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSA 1566
++ + P P + V +VT K FD+ I IGLN++TM +++Y+
Sbjct: 2142 RRRMHEPPYYTNYSP---TRMFVHNVVTSKYFDLAIAAVIGLNVVTMAMEYYKMPSGLKY 2198
Query: 1567 VLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYF- 1624
L N F +F E +K+ AL + Y + WN D +V+ SI+ +VL ++
Sbjct: 2199 ALKIFNYFFTAVFILEANMKLVALGWKLYLKDRWNQLDVGIVLLSIVGIVLEELETNTHQ 2258
Query: 1625 ---VSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAI 1681
++PT++RV+RV ++ RVL+L+K A GIR LL + +LP + N+ LL FL+ FIFA
Sbjct: 2259 IIPINPTIIRVMRVLRIARVLKLLKMANGIRALLDTVMQALPQVGNLGLLFFLLFFIFAA 2318
Query: 1682 FGMSFF--MHVKDK---GGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDL 1736
G+ F + D+ GL + +F F + + LF+++T W+G++ + + D
Sbjct: 2319 LGVELFGRLECSDEIPCQGLGEHAHFANFGMAFLTLFRVATGDNWNGIMKDTLRDNCDDA 2378
Query: 1737 PDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGL 1791
D R C S+ I + + +++++ +++N+ +AV++++ ++ + +++ L
Sbjct: 2379 ADCVRNC---CVSSVIAPIFFVIFVLMAQFVLVNVVVAVLMKHLEESHKQMEDEL 2430
Score = 105 bits (253), Expect = 9e-21
Identities = 91/323 (28%), Positives = 157/323 (48%), Gaps = 56/323 (17%)
Query: 137 ILVHPLFSLFIITTILVNCILMIMPTTPTVESTEV--------IFTGI----YTFESAVK 184
++ +P F I IL+NCI + M P V+ V IF I + E +K
Sbjct: 2 LITNPWFERVSILVILLNCITLGM-YQPCVDDACVTNRCKILQIFDDIIFAFFALEMTIK 60
Query: 185 VMARGFILQPFTYLRDAWNWLDFVVIA---LAYVTMGIDLGNLAALRTFRVLRALKTVAI 241
++A G I TYL D+WN LDF ++ L YV M ++ NL A+RT RVLR L+ +
Sbjct: 61 MVAMG-ICGKNTYLADSWNRLDFFIVLAGLLEYV-MHVENLNLTAIRTIRVLRPLRAINR 118
Query: 242 VPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGN 301
+P ++ +V +++++ L +V++L F +F ++G+Q++ G+L Q+C + +G
Sbjct: 119 IPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWEGILRQRC-SLMRTEGMVYP 177
Query: 302 LTDENWERFCQNETNWYGEGGD--YPLCGN----SSGAGQC----------EPG------ 339
LT + F +++ D LCGN G+ C EP
Sbjct: 178 LTLSQYYEFSKDQDYICSTPNDSGMHLCGNFPPYRIGSLVCNEEAKLFDFNEPTNTSCVN 237
Query: 340 ----YVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ-----------LFF 384
Y + G NP G SFD G A+++ F +++ + W ++ ++F
Sbjct: 238 WNQYYTTCKQSGENPFQGTISFDNIGMAWVAIFLVISLEGWTDIMYYVQDAHSFWDWIYF 297
Query: 385 VVIIFLGSFYLVNLILAIVAMSY 407
V++I +GSF+++NL L ++A +
Sbjct: 298 VLLIVIGSFFMINLCLVVIATQF 320
Score = 97.1 bits (231), Expect = 4e-18
Identities = 58/163 (35%), Positives = 88/163 (53%), Gaps = 9/163 (5%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQ--DILYYMDRIFTVIFFIEMLIKW 1271
LI N +FE I +ILL+ + L + + + IL D I F +EM IK
Sbjct: 2 LITNPWFERVSILVILLNCITLGMYQPCVDDACVTNRCKILQIFDDIIFAFFALEMTIKM 61
Query: 1272 LALGF---QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMS 1328
+A+G Y ++W LDF IV+ L+ +V + +RT+R LRPLRA++
Sbjct: 62 VAMGICGKNTYLADSWNRLDFFIVLAGLLEYVMHVENLN----LTAIRTIRVLRPLRAIN 117
Query: 1329 RMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
R+ MR++V L+ +P + NVLL+C + IF I+GVQL+ G
Sbjct: 118 RIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWEG 160
Score = 94.7 bits (225), Expect = 2e-17
Identities = 75/308 (24%), Positives = 145/308 (47%), Gaps = 33/308 (10%)
Query: 1197 DSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMD 1256
+ P++ + R+ ++ + YF+ A+ +I L+ + +A+E +P L+ L +
Sbjct: 2147 EPPYYTNYSPTRMFVHNVVTSKYFDLAIAAVIGLNVVTMAMEYYKMPSG--LKYALKIFN 2204
Query: 1257 RIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQ------ 1310
FT +F +E +K +ALG++ Y + W LD IV++S++ V Q
Sbjct: 2205 YFFTAVFILEANMKLVALGWKLYLKDRWNQLDVGIVLLSIVGIVLEELETNTHQIIPINP 2264
Query: 1311 -AFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
+ MR LR R L+ + G+R +++ ++QA+P + N+ L+ + + IFA +GV+LF
Sbjct: 2265 TIIRVMRVLRIARVLKLLKMANGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELF 2324
Query: 1370 AGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWI 1429
G+ +C D IP + +F + G A+L LF+VAT W
Sbjct: 2325 -GR-LECSDE---------IPCQGL---------GEHAHFANFGMAFLTLFRVATGDNWN 2364
Query: 1430 QIMNDAI-DSREVGRQPIRE---TNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKK 1485
IM D + D+ + +R +++ ++ +N+ + V++ + E K
Sbjct: 2365 GIMKDTLRDNCDDAADCVRNCCVSSVIAPIFFVIFVLMAQFVLVNVVVAVLMKHLEESHK 2424
Query: 1486 KAGGSLEM 1493
+ L+M
Sbjct: 2425 QMEDELDM 2432
Score = 85.8 bits (203), Expect = 1e-14
Identities = 56/199 (28%), Positives = 107/199 (53%), Gaps = 5/199 (2%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL- 1590
+V K F I+L I +N L+M ++++ Q +A+++ N++F IF+ E LLK+ A
Sbjct: 932 LVEHKYFQQGILLAILINTLSMGIEYHNQPPELTAIVETSNVVFSGIFAVEMLLKVVAEG 991
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
+ Y +N+FD ++V+ S + + + + + L V+R ++ R+L+LV+
Sbjct: 992 PFRYIANGFNVFDGIIVILSAIEICQTFMGNGTGGGGSGLSVLRTFRLLRILKLVRFMPN 1051
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF--MHVKDKGG--LDDVYNFKTFV 1706
+R LF + ++ + LL L +FIF+I GM+ F + G + D NF + +
Sbjct: 1052 LRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMNLFGCKFCEKVNGEMICDRKNFDSLL 1111
Query: 1707 QSMILLFQMSTSAGWDGVL 1725
+++ +FQ+ T W+ VL
Sbjct: 1112 WALVTVFQILTQEDWNVVL 1130
Score = 83.0 bits (196), Expect = 7e-14
Identities = 67/277 (24%), Positives = 134/277 (48%), Gaps = 36/277 (12%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
+L+E+ YF+ ++ IL+++L++ +E + P P L I+ + +F+ IF +EML+K +
Sbjct: 931 RLVEHKYFQQGILLAILINTLSMGIEYHNQP--PELTAIVETSNVVFSGIFAVEMLLKVV 988
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFVAALCG---AGGIQAFKTMRTLRALRPLRAMSR 1329
A G +Y N + D IIV++S I G GG +RT R LR L+ +
Sbjct: 989 AEGPFRYIANGFNVFDGIIVILSAIEICQTFMGNGTGGGGSGLSVLRTFRLLRILKLVRF 1048
Query: 1330 MQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEII 1389
M +R + +++ + ++ + ++F IF+I+G+ LF K+ C +N E+I
Sbjct: 1049 MPNLRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMNLFGCKF--CEKVN-----GEMI 1101
Query: 1390 PDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRET 1449
D+ NFD + A + +FQ+ T + W ++ + ++ +T
Sbjct: 1102 CDRK--------------NFDSLLWALVTVFQILTQEDWNVVLFNGME----------KT 1137
Query: 1450 NIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
+ + LY NL + ++++ F+ ++ +
Sbjct: 1138 SHWAALYFVALMTFGNYVLFNLLVAILVEGFSSERNE 1174
Score = 71.7 bits (168), Expect = 2e-10
Identities = 48/168 (28%), Positives = 88/168 (52%), Gaps = 20/168 (11%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMP-------TTPTVESTEVIFTGIYTFESA 182
IRR ++ H F I+ IL+N + M + T VE++ V+F+GI+ E
Sbjct: 925 IRRYIRRLVEHKYFQQGILLAILINTLSMGIEYHNQPPELTAIVETSNVVFSGIFAVEML 984
Query: 183 VKVMARGFILQPFTYLRDAWNWLDFVVIALAYVT-----MGIDLGN----LAALRTFRVL 233
+KV+A G PF Y+ + +N D +++ L+ + MG G L+ LRTFR+L
Sbjct: 985 LKVVAEG----PFRYIANGFNVFDGIIVILSAIEICQTFMGNGTGGGGSGLSVLRTFRLL 1040
Query: 234 RALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
R LK V +P L+ + ++ ++ N+ L + + +F+++G+ ++
Sbjct: 1041 RILKLVRFMPNLRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMNLF 1088
Score = 71.7 bits (168), Expect = 2e-10
Identities = 45/183 (24%), Positives = 94/183 (51%), Gaps = 20/183 (10%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM--PTTPTVESTE------- 170
+L+I N R++ + + F ++ I +NCI + M P P STE
Sbjct: 1829 SLYIFPEDNRFRQICTWFVNQKWFDNVVLLFIALNCITLAMERPNIPP-SSTERLFLATA 1887
Query: 171 -VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA--- 226
+FT ++T E +KV+A G Y WN +D ++ ++ + + + L + ++
Sbjct: 1888 NYVFTVVFTVEMFIKVVATGMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSLISESSPRI 1947
Query: 227 ---LRTFRVLRALKTVAIV---PGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
LR FR+LR+L+ + ++ PGLK +V ++ S++ + +++++ +F ++G+Q+
Sbjct: 1948 FGILRVFRLLRSLRPLRVINRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQL 2007
Query: 281 YMG 283
+ G
Sbjct: 2008 FKG 2010
Score = 61.3 bits (142), Expect = 3e-07
Identities = 48/166 (28%), Positives = 81/166 (48%), Gaps = 19/166 (11%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAV------LDYLNMIFIVIFSSECLL 1585
++T+ F+ + +L I LN +T+ + YQ + V L + I F+ E +
Sbjct: 2 LITNPWFERVSILVILLNCITLGM--YQPCVDDACVTNRCKILQIFDDIIFAFFALEMTI 59
Query: 1586 KIFAL----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRV 1641
K+ A+ + Y + WN DF +V+ +L V+ +E ++ T +R +RV R
Sbjct: 60 KMVAMGICGKNTYLADSWNRLDFFIVLAGLLEYVMH--VEN--LNLTAIRTIRVL---RP 112
Query: 1642 LRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
LR + +R L+ L +LP L N+ LL F V FIF I G+ +
Sbjct: 113 LRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLW 158
Score = 51.2 bits (117), Expect = 3e-04
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L++ LR+ KL + P L + +M RTM + +L + IFIF+++GM LFG +
Sbjct: 1034 LRTFRLLRILKLVRFMPNLRRQLFVMLRTMDNVAVFFSLLVLFIFIFSILGMNLFGCKFC 1093
Query: 887 DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE 919
+ V+ D R NF + + + VF++L E
Sbjct: 1094 EKVNGEMICD--RKNFDSLLWALVTVFQILTQE 1124
Score = 49.2 bits (112), Expect = 0.001
Identities = 38/175 (21%), Positives = 83/175 (47%), Gaps = 24/175 (13%)
Query: 127 FNPIRRVAIYILVHPLFSLFIITTILVNCILMIMP--TTPT-----VESTEVIFTGIYTF 179
++P R ++ F L I I +N + M M P+ ++ FT ++
Sbjct: 2154 YSPTRMFVHNVVTSKYFDLAIAAVIGLNVVTMAMEYYKMPSGLKYALKIFNYFFTAVFIL 2213
Query: 180 ESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV-------------TMGIDLGNLAA 226
E+ +K++A G+ L YL+D WN LD ++ L+ V + I+ +
Sbjct: 2214 EANMKLVALGWKL----YLKDRWNQLDVGIVLLSIVGIVLEELETNTHQIIPINPTIIRV 2269
Query: 227 LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+R R+ R LK + + G++ ++ V++++ + ++ +L +FA +G++++
Sbjct: 2270 MRVLRIARVLKLLKMANGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELF 2324
Score = 47.6 bits (108), Expect = 0.003
Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 4/97 (4%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
RV KL K + L+ + + + +GNL + ++ FIFA +G++LFG+ ++ D P
Sbjct: 2277 RVLKLLKMANGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELFGR--LECSDEIP 2334
Query: 894 -DGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
G +F +F +F+ +FRV G+ W M D +
Sbjct: 2335 CQGLGEHAHFANFGMAFLTLFRVATGDNWNGIMKDTL 2371
Score = 36.7 bits (81), Expect = 6.4
Identities = 15/56 (26%), Positives = 33/56 (58%)
Query: 826 ALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
A+++ LR + P++ +L+ ++ T+ LGN+ + + FIF ++G+QL+
Sbjct: 103 AIRTIRVLRPLRAINRIPSMRILVMLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLW 158
Score = 36.7 bits (81), Expect = 6.4
Identities = 14/49 (28%), Positives = 27/49 (55%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
LR ++ P L L++ + ++ +GN+ + C IF ++G+QLF
Sbjct: 1960 LRPLRVINRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLF 2008
>UniRef50_Q4RGG8 Cluster: Chromosome 18 SCAF15100, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 18 SCAF15100, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1599
Score = 289 bits (708), Expect = 7e-76
Identities = 173/595 (29%), Positives = 307/595 (51%), Gaps = 35/595 (5%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEM 1267
RL +I + F+ V+ I L+ + +ALE + + + L + IFT IF EM
Sbjct: 826 RLLCQSIIAHKLFDYVVLVFIFLNCITVALERPKILQGSVERVFLTISNYIFTTIFVAEM 885
Query: 1268 LIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQA-FKTMRTLRALR 1322
+K +++G + Y ++W LD +V VSLI+ V ++ G I + +R LR LR
Sbjct: 886 TVKVVSMGLYLGEKAYLRSSWNILDGFLVFVSLIDIVVSMAGGAKILGVLRVLRLLRTLR 945
Query: 1323 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHT 1382
PLR +SR G+++VV L+ ++ I N++L+C F++IF I+GVQLF GK++ CV +
Sbjct: 946 PLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYYCVGFDVK 1005
Query: 1383 TLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVG 1442
I +K+ C +Y W + NFD++G+A + LF +A+ GW+ IM +D+ +
Sbjct: 1006 N-----ITNKSDCLAASYRWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYHGLDAVAID 1060
Query: 1443 RQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFN--------EQKKKAGGSLEMF 1494
+QP+ N +M LY LN+F+GV+++NF+ E+ ++ +
Sbjct: 1061 QQPVTNNNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEVEEARRREEKRQRR 1120
Query: 1495 MTEDQKKYYNAMKKMGSKKPLKAIPRPRWR----PQAIVFEIVTDKKFDMIIMLFIGLNM 1550
M + +++++ + +A P + + + + T D++I I +N+
Sbjct: 1121 MEKKRRRWFLFRLPLTPSPSSEAQKLPYYASYGPARLAIHTLCTSHYLDLVITFIICINV 1180
Query: 1551 LTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFS 1610
+TM+L+HY Q ++ L Y N +F F E LK+ A + F + FD + +
Sbjct: 1181 ITMSLEHYSQPQSLETALKYCNYVFTSTFVIEASLKLVAFGFRRFFKDRLRFDLIALCVC 1240
Query: 1611 ILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICL 1670
+ + S+ ++PT++R++RV ++ RVL+L+K A G+R LL + +LP + N+ L
Sbjct: 1241 VCVEIESN--ASLPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGL 1298
Query: 1671 LLFLVMFIFAIFGMSFFMHVKDKG-----GLDDVYNFKTFVQSMILLFQMSTSAGWDGVL 1725
L L+ FI+A G+ F + G+ F+ F + + LFQ+ST W+G++
Sbjct: 1299 LFMLLFFIYAALGVELFGELVCNADYPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIM 1358
Query: 1726 DGIINEEECDLPDNERGSPGNC--GSATIGITYLLSYLVISFLIVINMYIAVILE 1778
+ EC P GS C G I Y +S+++ + ++IN+ +A LE
Sbjct: 1359 KDTL--REC--PPGGSGSDYGCHAGLQFISPLYFVSFVLTAQFVLINVVVADSLE 1409
Score = 109 bits (262), Expect = 8e-22
Identities = 66/203 (32%), Positives = 116/203 (57%), Gaps = 14/203 (6%)
Query: 1529 VFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIF 1588
++EIV K F+ IM+ I +N ++M ++H++Q E + +L+ N++F +FS E +LK+
Sbjct: 368 LWEIVESKYFNRGIMIAILINTISMGIEHHEQPEELTNILEICNIVFTSMFSLEMILKLT 427
Query: 1589 AL-RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKG 1647
A ++Y P+N+FD V+V+ S+ +V S L V+R ++ RVL+LV+
Sbjct: 428 AFGSFNYLRNPYNVFDGVIVIISVCEIVGQ--------SDGGLSVLRTFRLLRVLKLVRF 479
Query: 1648 AKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF---MHVKDKGG--LDDVYNF 1702
+R L L ++ + C+LL L +FIF+I GM F +K + G + D NF
Sbjct: 480 MPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSIKTETGDTVPDRKNF 539
Query: 1703 KTFVQSMILLFQMSTSAGWDGVL 1725
+ + +++ +FQ+ T W+GVL
Sbjct: 540 DSLLWAIVTVFQILTQEDWNGVL 562
Score = 87.4 bits (207), Expect = 3e-15
Identities = 49/180 (27%), Positives = 92/180 (51%), Gaps = 16/180 (8%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVEST---------E 170
++++ P N R + I+ H LF ++ I +NCI + + ++ +
Sbjct: 815 SVYLFSPQNKFRLLCQSIIAHKLFDYVVLVFIFLNCITVALERPKILQGSVERVFLTISN 874
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID-------LGN 223
IFT I+ E VKV++ G L YLR +WN LD ++ ++ + + + LG
Sbjct: 875 YIFTTIFVAEMTVKVVSMGLYLGEKAYLRSSWNILDGFLVFVSLIDIVVSMAGGAKILGV 934
Query: 224 LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
L LR R LR L+ ++ PGLK +V +I S+K + +++++ +F ++G+Q++ G
Sbjct: 935 LRVLRLLRTLRPLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLFKG 994
Score = 87.0 bits (206), Expect = 5e-15
Identities = 47/170 (27%), Positives = 94/170 (55%), Gaps = 7/170 (4%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W R+K ++++E+ YF ++ IL++++++ +E P L +IL + +FT +F
Sbjct: 361 WYDTRMKLWEIVESKYFNRGIMIAILINTISMGIEHHEQPEE--LTNILEICNIVFTSMF 418
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRP 1323
+EM++K A G Y N + D +IV++S+ V GG+ +T R LR L+
Sbjct: 419 SLEMILKLTAFGSFNYLRNPYNVFDGVIVIISVCEIVGQ--SDGGLSVLRTFRLLRVLKL 476
Query: 1324 LRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
+R M ++ VV L++ + ++ ++ ++F IF+I+G+ +F K+
Sbjct: 477 VRFMPALRRQLVV---LMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKF 523
Score = 87.0 bits (206), Expect = 5e-15
Identities = 70/281 (24%), Positives = 129/281 (45%), Gaps = 36/281 (12%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQ--QSETFSAVLDYLNMIFIVIFSSECLLKIFA 1589
I+ K FD ++++FI LN +T+ L+ + Q L N IF IF +E +K+ +
Sbjct: 832 IIAHKLFDYVVLVFIFLNCITVALERPKILQGSVERVFLTISNYIFTTIFVAEMTVKVVS 891
Query: 1590 LRYH-----YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRL 1644
+ + Y WN+ D +V S++ +V+S + +LRV+R+ + R LR+
Sbjct: 892 MGLYLGEKAYLRSSWNILDGFLVFVSLIDIVVSMAGGAKILG--VLRVLRLLRTLRPLRV 949
Query: 1645 VKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF---------MHVKDKGG 1695
+ A G++ ++ L SL + NI L+ IF I G+ F VK+
Sbjct: 950 ISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYYCVGFDVKNITN 1009
Query: 1696 LDDV-----------YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSP 1744
D YNF Q+++ LF +++ GW ++ ++ D +P
Sbjct: 1010 KSDCLAASYRWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYHGLDAVAIDQQPVTNNNP 1069
Query: 1745 GNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATE 1785
+ Y +S+L+I V+NM++ V++EN+ + +
Sbjct: 1070 WM-------LLYFISFLLIVSFFVLNMFVGVVVENFHKCRQ 1103
Score = 69.3 bits (162), Expect = 1e-09
Identities = 43/147 (29%), Positives = 81/147 (55%), Gaps = 12/147 (8%)
Query: 143 FSLFIITTILVNCILMIMP-------TTPTVESTEVIFTGIYTFESAVKVMARGFILQPF 195
F+ I+ IL+N I M + T +E ++FT +++ E +K+ A G F
Sbjct: 377 FNRGIMIAILINTISMGIEHHEQPEELTNILEICNIVFTSMFSLEMILKLTAFG----SF 432
Query: 196 TYLRDAWNWLDFVVIALAYVTM-GIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIE 254
YLR+ +N D V++ ++ + G G L+ LRTFR+LR LK V +P L+ + +++
Sbjct: 433 NYLRNPYNVFDGVIVIISVCEIVGQSDGGLSVLRTFRLLRVLKLVRFMPALRRQLVVLMK 492
Query: 255 SVKNLRDVIILTMFSLSVFALMGLQIY 281
++ N+ +L M + +F+++G+ I+
Sbjct: 493 TMDNVATFCMLLMLFIFIFSILGMHIF 519
Score = 51.6 bits (118), Expect = 2e-04
Identities = 33/119 (27%), Positives = 59/119 (49%), Gaps = 8/119 (6%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY- 885
L++ LRV KL + P L + ++ +TM + +L + IFIF+++GM +FG +
Sbjct: 465 LRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFS 524
Query: 886 --VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSCIPFFLA 941
+ D PD R NF + + + VF++L E W +++ M +F+A
Sbjct: 525 IKTETGDTVPD----RKNFDSLLWAIVTVFQILTQEDWNGVLYNGMAATSPLAALYFVA 579
Score = 44.0 bits (99), Expect = 0.042
Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 2/96 (2%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
RV KL K + L+ + + + +GNL + ++ FI+A +G++LFG+ V D
Sbjct: 1268 RVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGE-LVCNADYPC 1326
Query: 894 DGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
+G F +F +F+ +F+V G+ W M D +
Sbjct: 1327 EGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTL 1362
Score = 38.3 bits (85), Expect = 2.1
Identities = 17/54 (31%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF-GKNY 885
LR ++ P L L++ + ++ +GN+ + C IF ++G+QLF GK Y
Sbjct: 944 LRPLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLFKGKFY 997
Score = 37.9 bits (84), Expect = 2.8
Identities = 13/32 (40%), Positives = 24/32 (75%)
Query: 1407 MNFDHVGKAYLCLFQVATFKGWIQIMNDAIDS 1438
+NFD++ A++ +FQV T +GW++IM +D+
Sbjct: 126 INFDNIAYAWIVIFQVITLEGWVEIMYYVMDA 157
Score = 37.1 bits (82), Expect = 4.9
Identities = 19/63 (30%), Positives = 36/63 (57%), Gaps = 11/63 (17%)
Query: 356 SFDTFGWAFLSAFRLMTQDYWEN-LYQ----------LFFVVIIFLGSFYLVNLILAIVA 404
+FD+ WA ++ F+++TQ+ W LY L+FV ++ G++ L NL++AI+
Sbjct: 538 NFDSLLWAIVTVFQILTQEDWNGVLYNGMAATSPLAALYFVALMTFGNYVLFNLLVAILV 597
Query: 405 MSY 407
+
Sbjct: 598 EGF 600
>UniRef50_Q963L8 Cluster: High voltage-activated calcium channel
Cav2A; n=2; Schistosoma|Rep: High voltage-activated
calcium channel Cav2A - Schistosoma mansoni (Blood fluke)
Length = 2203
Score = 289 bits (708), Expect = 7e-76
Identities = 214/758 (28%), Positives = 367/758 (48%), Gaps = 62/758 (8%)
Query: 1161 KTDIKVGADEDVVDDTPADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYF 1220
+TDI+ G ++D + + + C + P L F R F ++ YF
Sbjct: 792 QTDIEPGREQDTQANQESQTQHQLCGK--PMLPYSSMFIFSSTNPVRRFCHF-VVNLRYF 848
Query: 1221 ETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGF---- 1276
+ ++ +I+ SSLALA ED + I +L Y D FT +F IEML+K + LG
Sbjct: 849 DLFIMIVIVSSSLALAAEDP-VSENSIRNCLLEYFDHAFTCVFAIEMLLKLIDLGVFLHP 907
Query: 1277 QKYFTNAWCWLDFIIVMVSLINFVAA--LCGAGG------IQAFKTMRTLRALRPLRAMS 1328
Y + W LD +V+ +LI+F A L G G + K++R LR LRPL+ +
Sbjct: 908 YSYCRDTWNLLDAAVVIGALISFFRAYTLKGRAGHGSSKNLSTIKSLRVLRVLRPLKTIR 967
Query: 1329 RMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH-- 1386
R+ ++ V + +V ++ ++ +L+V ++F IF+I+ VQLF GK+F C D++ T
Sbjct: 968 RVPKLKAVFDCVVSSLKNVCIILVVYILFQFIFSIVAVQLFQGKFFYCNDLSKLTKEDCQ 1027
Query: 1387 ---EIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGR 1443
D ++ W + ++D+V A L LF V T +GW I+ +++D+ EV
Sbjct: 1028 GYFFSYDDGLVPVVKARVWSSRDFHYDNVITAMLTLFTVTTGEGWPGILKNSMDATEVNH 1087
Query: 1444 QPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYY 1503
P+ + + M ++ +N+F+ +II F EQ G E+ E K
Sbjct: 1088 GPVEDHSQQMAIFYIIFFIVFPFFFVNIFVALIIITFQEQ-----GENELVDHELDKNQK 1142
Query: 1504 NAMKKMGSKKPL-KAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHY---- 1558
++ + KPL + +P + ++ +V F+ IM I LN L + + +Y
Sbjct: 1143 QCIEFAINSKPLCRYMPSNIASTKYRIWRLVVSSPFEYYIMTMIALNTLILMMKYYRPDY 1202
Query: 1559 ------------QQSETFSAVLDYLNMIFIVIFSSECLLKIFALR-YHYFVEPWNLFDFV 1605
Q+ ++ + L YLN F +F+ ECLLK+ A YF + WN FDF+
Sbjct: 1203 TDANMGIPDWETQKYQSHCSTLVYLNTAFTAMFTMECLLKLIAFGPKSYFRDSWNTFDFI 1262
Query: 1606 VVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPAL 1665
V+ SI +++S++ + F++ LR+ R A R+++L++ IR LL+ S AL
Sbjct: 1263 TVVGSITDVLVSELQDSSFLNLGFLRLFRAA---RLIKLIRHGYTIRILLWTFIQSFKAL 1319
Query: 1666 FNICLLLFLVMFIFAIFGMSFFMHV---KDKGGLDDVYNFKTFVQSMILLFQMSTSAGWD 1722
+CLL+ ++ FI+A+ GM F + + +G + NF +F +++LLF+ +T W
Sbjct: 1320 PYVCLLITMLFFIYAVVGMQIFGTIATNEAEGQITSYNNFHSFPYAVLLLFRCATGESWQ 1379
Query: 1723 GVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQ 1782
++ +EC R S NCGS TY +S+ +++N+++AVI++N+
Sbjct: 1380 EIMLACTYGQEC----VNRAS-NNCGS-NASYTYFVSFNFFCSFLMLNLFVAVIVDNFDY 1433
Query: 1783 ATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHKPNKY---- 1838
T D L D + +W +DP I Y ++ + L LEPP+ + Y
Sbjct: 1434 LTRD-SPILGSHHLDEFIRVWAEYDPGAKGRIHYTEMYEMLRKLEPPVGFGQNCPYRLAY 1492
Query: 1839 -KIISMDIPICRGDMMFCVDILDALTKDFFARKGNPIE 1875
K+I M++P+ + L AL ++ K P E
Sbjct: 1493 KKLIRMNMPLDSAGTVHFTTTLFALVRESLGIKMAPAE 1530
Score = 162 bits (394), Expect = 8e-38
Identities = 105/315 (33%), Positives = 169/315 (53%), Gaps = 37/315 (11%)
Query: 116 SATN-ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM----------PTTP 164
S+TN AL++ N IR+ A I+ F +++TI+ NC+++ M P +
Sbjct: 57 SSTNRALFVFSKNNLIRKAARNIIEWGPFEYMVLSTIIANCVVLAMEVHLPNKDKRPLSE 116
Query: 165 TVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLG-- 222
+E TE F GI+T E+ +K++A GFIL +YLR+ WN LDFVV+ ++TM + G
Sbjct: 117 KLEITENYFLGIFTCEAFLKIIALGFILHSGSYLRNIWNILDFVVVVTGFLTMFMTSGSG 176
Query: 223 -NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
NL LR RVLR LK V+ VP L+ ++ ++I+++ L + IL +F++ +FA++GL+ Y
Sbjct: 177 VNLRTLRAVRVLRPLKLVSGVPSLQVVLTSIIKAMAPLLQIGILVLFAILIFAIVGLEFY 236
Query: 282 MGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYV 341
GV C + + D CQ GA C GY+
Sbjct: 237 SGVFHVTCFEQSNPTELPSFIPDAPGLVPCQ----------PVDTHTRPPGAFICPAGYI 286
Query: 342 CLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWEN-LYQ-----------LFFVVIIF 389
C +G+ PNYG TSFD G+A L+ F+ +T + W + LY ++F+ +I
Sbjct: 287 C-KGYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDVLYMTNRTYGSRFNWIYFIPLIV 345
Query: 390 LGSFYLVNLILAIVA 404
+G+F L+NL+L +++
Sbjct: 346 IGAFLLINLVLGVLS 360
Score = 101 bits (243), Expect = 2e-19
Identities = 89/332 (26%), Positives = 147/332 (44%), Gaps = 41/332 (12%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEM 1267
R +LI++ F VIT++LL++L +++E P L D LY+ + IF +F EM
Sbjct: 472 RFAVRRLIKSQKFYIIVITLVLLNALCVSVEFYGQPGW--LTDFLYFSEFIFLGLFLFEM 529
Query: 1268 LIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAM 1327
+IK LG YF + + DF +V SL V + F +R++R LR +
Sbjct: 530 IIKIYGLGCLIYFHSTFNIFDFAVVFASLFEIVWQIFYPSDSFGFSALRSIRLLRIFKIT 589
Query: 1328 SRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHE 1387
+R +V +L+ A+ SI ++L + +F LIFA++G+QLF G++
Sbjct: 590 RYWASLRNLVLSLLNAMRSILSLLFLLFLFMLIFALLGMQLFGGEF-------------- 635
Query: 1388 IIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIR 1447
N+ NFD KA L +FQ+ T + W IM D I S + +
Sbjct: 636 -----------NFDDGKPGQNFDTFVKALLTVFQILTGEDWNMIMYDGIRS----QGGVN 680
Query: 1448 ETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNF-NEQKKKAGGSLEMFMTEDQKKYYNAM 1506
+Y LN+F+ + +DN N Q+ A E+Q+
Sbjct: 681 NGGFVYCIYFVLLALFGNYTLLNVFLAIAVDNLANAQELTAAEE------EEQRLANELA 734
Query: 1507 KKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKF 1538
++ K+ LK +PQ I + ++K+
Sbjct: 735 EQQEDKENLKTDLN---QPQTIEINQINERKY 763
Score = 95.9 bits (228), Expect = 1e-17
Identities = 81/312 (25%), Positives = 151/312 (48%), Gaps = 46/312 (14%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPH---RPILQDILYYMDRIFTVIF 1263
+R +IE FE V++ I+ + + LA+E VHLP+ RP L + L + F IF
Sbjct: 72 IRKAARNIIEWGPFEYMVLSTIIANCVVLAME-VHLPNKDKRP-LSEKLEITENYFLGIF 129
Query: 1264 FIEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLR 1319
E +K +ALGF Y N W LDF++V+ + + G+ +T+R +R
Sbjct: 130 TCEAFLKIIALGFILHSGSYLRNIWNILDFVVVVTGFLTMF--MTSGSGVN-LRTLRAVR 186
Query: 1320 ALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKCVD 1378
LRPL+ +S + ++VV+ ++++A+ + + ++ L LIFAI+G++ ++G + C +
Sbjct: 187 VLRPLKLVSGVPSLQVVLTSIIKAMAPLLQIGILVLFAILIFAIVGLEFYSGVFHVTCFE 246
Query: 1379 MNHTTLSHEIIPDKNA---C-TLENYT-----------------WEN---SPMNFDHVGK 1414
++ T IPD C ++ +T WE +FD++G
Sbjct: 247 QSNPTELPSFIPDAPGLVPCQPVDTHTRPPGAFICPAGYICKGYWEGPNYGITSFDNIGY 306
Query: 1415 AYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIG 1474
A L +FQ T +GW ++ + +R G + + ++Y +NL +G
Sbjct: 307 AMLTVFQCITMEGWTDVL--YMTNRTYGSR-------FNWIYFIPLIVIGAFLLINLVLG 357
Query: 1475 VIIDNFNEQKKK 1486
V+ F +++++
Sbjct: 358 VLSGEFAKERER 369
Score = 95.9 bits (228), Expect = 1e-17
Identities = 68/259 (26%), Positives = 131/259 (50%), Gaps = 17/259 (6%)
Query: 1529 VFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIF 1588
V ++ +KF +I++ + LN L ++++ Y Q + L + IF+ +F E ++KI+
Sbjct: 475 VRRLIKSQKFYIIVITLVLLNALCVSVEFYGQPGWLTDFLYFSEFIFLGLFLFEMIIKIY 534
Query: 1589 ALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKG 1647
L YF +N+FDF VV S+ +V + LR +R+ R+ ++ +
Sbjct: 535 GLGCLIYFHSTFNIFDFAVVFASLFEIVWQIFYPSDSFGFSALRSIRLL---RIFKITRY 591
Query: 1648 AKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQ 1707
+R L+ +L ++ ++ ++ LLFL M IFA+ GM F + NF TFV+
Sbjct: 592 WASLRNLVLSLLNAMRSILSLLFLLFLFMLIFALLGMQLFGGEFNFDDGKPGQNFDTFVK 651
Query: 1708 SMILLFQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFL 1766
+++ +FQ+ T W+ ++ DGI +G N G I ++L L ++
Sbjct: 652 ALLTVFQILTGEDWNMIMYDGI----------RSQGGVNN-GGFVYCIYFVLLALFGNYT 700
Query: 1767 IVINMYIAVILENYSQATE 1785
+ +N+++A+ ++N + A E
Sbjct: 701 L-LNVFLAIAVDNLANAQE 718
Score = 82.2 bits (194), Expect = 1e-13
Identities = 54/188 (28%), Positives = 98/188 (52%), Gaps = 24/188 (12%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVEST--------- 169
++++I NP+RR +++ F LFI+ ++V+ L + P E++
Sbjct: 824 SSMFIFSSTNPVRRFCHFVVNLRYFDLFIMI-VIVSSSLALAAEDPVSENSIRNCLLEYF 882
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVI--AL-----AYVTMGI--- 219
+ FT ++ E +K++ G L P++Y RD WN LD V+ AL AY G
Sbjct: 883 DHAFTCVFAIEMLLKLIDLGVFLHPYSYCRDTWNLLDAAVVIGALISFFRAYTLKGRAGH 942
Query: 220 ----DLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFAL 275
+L + +LR RVLR LKT+ VP LK + V+ S+KN+ ++++ + +F++
Sbjct: 943 GSSKNLSTIKSLRVLRVLRPLKTIRRVPKLKAVFDCVVSSLKNVCIILVVYILFQFIFSI 1002
Query: 276 MGLQIYMG 283
+ +Q++ G
Sbjct: 1003 VAVQLFQG 1010
Score = 69.3 bits (162), Expect = 1e-09
Identities = 48/137 (35%), Positives = 77/137 (56%), Gaps = 15/137 (10%)
Query: 792 VFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTL-NLLIS 850
+FD F +F +L +V +F D AL+S LR+FK+ + W +L NL++S
Sbjct: 548 IFD-FAVVFASLFEIVWQIFYPSDSFGFS-----ALRSIRLLRIFKITRYWASLRNLVLS 601
Query: 851 IMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFM 910
++ M ++ +L F+L + + IFA++GMQLFG + F DG P NF F+ + +
Sbjct: 602 LLN-AMRSILSLLFLLFLFMLIFALLGMQLFGGEF-----NFDDGK-PGQNFDTFVKALL 654
Query: 911 IVFRVLCGE-WIESMWD 926
VF++L GE W M+D
Sbjct: 655 TVFQILTGEDWNMIMYD 671
Score = 57.6 bits (133), Expect = 3e-06
Identities = 46/190 (24%), Positives = 93/190 (48%), Gaps = 21/190 (11%)
Query: 108 KGKDIFRFSATNALWILDPFNPIRRVAIYILVHPL-FSLFIITTILVNCILMIMP----- 161
K K F+ + AL+ ++ R A+ L+ F + +IT +L+N + + +
Sbjct: 451 KAKRNFKIPGSEALF---QYHKRFRFAVRRLIKSQKFYIIVITLVLLNALCVSVEFYGQP 507
Query: 162 --TTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVI--ALAYVTM 217
T + +E IF G++ FE +K+ G ++ Y +N DF V+ +L +
Sbjct: 508 GWLTDFLYFSEFIFLGLFLFEMIIKIYGLGCLI----YFHSTFNIFDFAVVFASLFEIVW 563
Query: 218 GI----DLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVF 273
I D +ALR+ R+LR K L+ +V +++ +++++ ++ L + +F
Sbjct: 564 QIFYPSDSFGFSALRSIRLLRIFKITRYWASLRNLVLSLLNAMRSILSLLFLLFLFMLIF 623
Query: 274 ALMGLQIYMG 283
AL+G+Q++ G
Sbjct: 624 ALLGMQLFGG 633
Score = 55.6 bits (128), Expect = 1e-05
Identities = 35/122 (28%), Positives = 60/122 (49%), Gaps = 10/122 (8%)
Query: 173 FTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVI------ALAYVTMGIDLGNLAA 226
FT ++T E +K++A G P +Y RD+WN DF+ + L NL
Sbjct: 1231 FTAMFTMECLLKLIAFG----PKSYFRDSWNTFDFITVVGSITDVLVSELQDSSFLNLGF 1286
Query: 227 LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLT 286
LR FR R +K + ++ ++ I+S K L V +L ++A++G+QI+ + T
Sbjct: 1287 LRLFRAARLIKLIRHGYTIRILLWTFIQSFKALPYVCLLITMLFFIYAVVGMQIFGTIAT 1346
Query: 287 QK 288
+
Sbjct: 1347 NE 1348
Score = 52.8 bits (121), Expect = 9e-05
Identities = 44/164 (26%), Positives = 78/164 (47%), Gaps = 20/164 (12%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHY---QQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY-- 1592
F+ +++ I N + + ++ + + S L+ F+ IF+ E LKI AL +
Sbjct: 85 FEYMVLSTIIANCVVLAMEVHLPNKDKRPLSEKLEITENYFLGIFTCEAFLKIIALGFIL 144
Query: 1593 ---HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
Y WN+ DFVVV+ L++ ++ S LR +R +V R L+LV G
Sbjct: 145 HSGSYLRNIWNILDFVVVVTGFLTMFMTS------GSGVNLRTLRAVRVLRPLKLVSGVP 198
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIF---GMSFFMHV 1690
++ +L ++ ++ L I +L V+F IF G+ F+ V
Sbjct: 199 SLQVVLTSIIKAMAPLLQIGIL---VLFAILIFAIVGLEFYSGV 239
Score = 45.6 bits (103), Expect = 0.014
Identities = 28/96 (29%), Positives = 51/96 (53%), Gaps = 6/96 (6%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
R+ KL + T+ +L+ ++ AL + ++ ++ FI+AV+GMQ+FG
Sbjct: 1294 RLIKLIRHGYTIRILLWTFIQSFKALPYVCLLITMLFFIYAVVGMQIFG----TIATNEA 1349
Query: 894 DGDLPRW-NFTDFMHSFMIVFRVLCGE-WIESMWDC 927
+G + + NF F ++ +++FR GE W E M C
Sbjct: 1350 EGQITSYNNFHSFPYAVLLLFRCATGESWQEIMLAC 1385
>UniRef50_Q963L7 Cluster: High voltage-activated calcium channel Cav1;
n=1; Schistosoma mansoni|Rep: High voltage-activated
calcium channel Cav1 - Schistosoma mansoni (Blood fluke)
Length = 1776
Score = 289 bits (708), Expect = 7e-76
Identities = 201/680 (29%), Positives = 348/680 (51%), Gaps = 55/680 (8%)
Query: 1218 TYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQ 1277
++F V+ IL+SS+ LA ED + P IL D FT +F +E+ +K ++ GF
Sbjct: 814 SHFGNIVLVCILVSSILLAAEDPLHANSP-RNRILNMFDYFFTSVFTVEITLKMISYGFV 872
Query: 1278 KYFTNAWC-----WLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG 1332
+ A+C LD I+V V+L++FV I A K +R LR LRPLRA++R +G
Sbjct: 873 LH-EGAFCRSVFNLLDLIVVCVALVSFVLQ---NQTISAVKILRVLRVLRPLRAINRAKG 928
Query: 1333 MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMN---HTTLSHEII 1389
++ VV ++ AI SI N++LV + +FA++GVQLF GK++ C D++ + I
Sbjct: 929 LKHVVQCMIIAIKSIGNIVLVTFLLEFMFAVIGVQLFKGKFYSCTDISKHVEEDCKGQFI 988
Query: 1390 PDKNAC----TLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQP 1445
K+ L W+NS NFD+V A L LF V+TF+GW ++ +IDS P
Sbjct: 989 EYKDMSLEDPILSEREWKNSDFNFDNVPNALLTLFAVSTFEGWPSLLYRSIDSNAEDHGP 1048
Query: 1446 IRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNA 1505
I + + +N+F+G +I F ++ + + E + ++Q+K
Sbjct: 1049 ITNYRPVVAFFYITFIILIPFFMINIFVGFVIVTFQKEGEAEYKNCE--LNKNQRKCI-- 1104
Query: 1506 MKKMGSKKPLKAIPRPRWRP----QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQS 1561
+ LKA PR R+ P Q ++ +V K+F+++I +FI +N + + L + +Q
Sbjct: 1105 ------EYALKARPRRRYIPKGHLQFKIWSVVVSKRFEILIFIFIFINTVALMLKYDKQG 1158
Query: 1562 ETFSAVLDYLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSLVL--SD 1618
+ + +LD N F +F+ E +L++ A + HYF + N+ DFV+V+ S + +++ SD
Sbjct: 1159 KLEARILDSFNYFFTAVFTVEFILRLSAFSFRHYFSDIGNVIDFVLVLGSYIDIIVTQSD 1218
Query: 1619 IIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFI 1678
I + F S R+ RV R+++L+ + IR LL+ S+ AL + LL+ ++ FI
Sbjct: 1219 ISQVKF-SVNFFRLFRVM---RLIKLLSKEESIRQLLWTFIKSIQALPYVALLIAMIFFI 1274
Query: 1679 FAIFGMSFFMHVK-DKGGLDDV--------YNFKTFVQSMILLFQMSTSAGWDGVLDGII 1729
+A+ GM F + ++ L++ NF+ F ++++LF+ +T W ++
Sbjct: 1275 YAVIGMQLFGQISIEENPLEEEEWPTLHRNNNFQNFFYALLVLFRCATGESWQDIMMACR 1334
Query: 1730 NEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQE 1789
++C E G CGS + Y +S+ IS +VIN+++AVI++N+ T D
Sbjct: 1335 EGQKCSKDSGETEVNG-CGS-KLAYAYFISFHAISAFLVINLFVAVIMDNFDYLTRD-WS 1391
Query: 1790 GLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQI-----HKPNKYKIISMD 1844
L D + W +DP+ +R+ + L + PPL H +K++ M+
Sbjct: 1392 ILGPHHLDEFITKWADYDPEAKGRVRHLDVVTMLGKISPPLGFGSMCPHTRACHKLVRMN 1451
Query: 1845 IPICRGDMMFCVDILDALTK 1864
+P+ +F L AL +
Sbjct: 1452 MPLNSDGTVFFNATLFALVR 1471
Score = 125 bits (302), Expect = 1e-26
Identities = 92/329 (27%), Positives = 160/329 (48%), Gaps = 45/329 (13%)
Query: 106 ISKGKDIFRFSATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM----- 160
+ K K +F +L ++ NP+RRV I I+ F FI+ TIL NC+ +
Sbjct: 42 VKKKKLCQQFRTDRSLCLMTKKNPLRRVCICIVDARPFEYFILATILCNCLALAFNHPYP 101
Query: 161 -----PTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV 215
+E E+ F I+T ESA+K++A GF+L YLR+ WN LDF ++ +
Sbjct: 102 GEDSNAVNQVLEKVELAFVIIFTTESALKIIAYGFVLHQDAYLRNFWNVLDFSIVLIGLS 161
Query: 216 TMGIDLGNL--AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVF 273
+ ++ N+ ALR FRVLR L+ ++ +P L+ ++ ++I ++ L + +L +F + V+
Sbjct: 162 SKALENMNIDVKALRAFRVLRPLRLLSGLPSLQVVLNSIITAMVPLLHIALLVIFVIIVY 221
Query: 274 ALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGA 333
A++GL+++ L C + +T R C ET+ G
Sbjct: 222 AIVGLELFQSKLHLTCYR--NSTHKIPEMTPN--PRPCTFETSSMG-----------FKC 266
Query: 334 GQCEPGYVCLQGFG------PNPNYGYTSFDTFGWAFLSAFRLMTQDYWENL-YQ----- 381
+ P Y C +G P G SFD F ++ L+ F +T + W + Y
Sbjct: 267 SELGPDYFCADMYGKEGERYTGPEGGIVSFDNFLYSMLTVFVCITMEGWTSTGYYVSDAI 326
Query: 382 ------LFFVVIIFLGSFYLVNLILAIVA 404
++FV ++ LGSF+++NL+L +++
Sbjct: 327 GSWWPWIYFVTLMVLGSFFVMNLVLGVLS 355
Score = 98.3 bits (234), Expect = 2e-18
Identities = 68/305 (22%), Positives = 152/305 (49%), Gaps = 29/305 (9%)
Query: 1497 EDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLD 1556
E+ + + + K L+ + + R R + V + ++ ++++ + LN + +T +
Sbjct: 422 EEPEMHVEEVVKTHCHSTLRRLRKFRKRTRRAVIAFINSRQCFALVIILVFLNTVVLTTE 481
Query: 1557 HYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSLV 1615
H+ Q E D+ N++F+ +F+ E ++K+ A + Y + +N FDF VV+FSIL L+
Sbjct: 482 HHNQPEWLDEFQDFANVVFVTLFTMEMVIKMGASXFSDYISKLFNRFDFFVVIFSILELL 541
Query: 1616 LSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLV 1675
++ ++P + V+R A++ R+ +L + + +R+L+ L S+ ++ ++ LLL +
Sbjct: 542 ---FVKSGLLNPMGVSVLRCARLLRIFKLTQYWESLRSLVGKLLKSVRSVASLLLLLSIF 598
Query: 1676 MFIFAIFGM-------SFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGI 1728
+ I ++ GM +F H K + NF +Q+M+ +FQ+ T W+ V+
Sbjct: 599 ILICSLLGMQLFGGRFNFIAHEKPRA------NFDGILQAMLTVFQILTGEDWNEVMYHG 652
Query: 1729 INEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQ 1788
+ E N + + Y + + I++N+++A+ ++N ++ ++
Sbjct: 653 MRAYE------------NSPWYGVVVIYFIFLFICGNYILLNVFLAIAVDNLNEDEDEED 700
Query: 1789 EGLTD 1793
E D
Sbjct: 701 EANGD 705
Score = 84.6 bits (200), Expect = 2e-14
Identities = 61/219 (27%), Positives = 103/219 (47%), Gaps = 16/219 (7%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRP-ILQDILYYMDRIFTVIFFI 1265
LR +++ FE ++ IL + LALA + + +L ++ F +IF
Sbjct: 66 LRRVCICIVDARPFEYFILATILCNCLALAFNHPYPGEDSNAVNQVLEKVELAFVIIFTT 125
Query: 1266 EMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRAL 1321
E +K +A GF Y N W LDF IV++ L + K +R R L
Sbjct: 126 ESALKIIAYGFVLHQDAYLRNFWNVLDFSIVLIGLSSKALENMNID----VKALRAFRVL 181
Query: 1322 RPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNH 1381
RPLR +S + ++VV+N+++ A+ + ++ L+ + +++AI+G++LF K N
Sbjct: 182 RPLRLLSGLPSLQVVLNSIITAMVPLLHIALLVIFVIIVYAIVGLELFQSKLHLTCYRNS 241
Query: 1382 TTLSHEIIPDKNACTLENYTWENSPMNF--DHVGKAYLC 1418
T E+ P+ C T+E S M F +G Y C
Sbjct: 242 THKIPEMTPNPRPC-----TFETSSMGFKCSELGPDYFC 275
Score = 78.2 bits (184), Expect = 2e-12
Identities = 62/261 (23%), Positives = 119/261 (45%), Gaps = 31/261 (11%)
Query: 1224 VITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNA 1283
VI ++ L+++ L E + P L + + + +F +F +EM+IK A F Y +
Sbjct: 467 VIILVFLNTVVLTTEHHNQPEW--LDEFQDFANVVFVTLFTMEMVIKMGASXFSDYISKL 524
Query: 1284 WCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQA 1343
+ DF +V+ S++ + G +R R LR + + +R +V L+++
Sbjct: 525 FNRFDFFVVIFSILELLFVKSGLLNPMGVSVLRCARLLRIFKLTQYWESLRSLVGKLLKS 584
Query: 1344 IPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWE 1403
+ S+ ++LL+ IF LI +++G+QLF G++ ++H E
Sbjct: 585 VRSVASLLLLLSIFILICSLLGMQLFGGRF--------NFIAH----------------E 620
Query: 1404 NSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXX 1463
NFD + +A L +FQ+ T + W ++M + + E P + +Y
Sbjct: 621 KPRANFDGILQAMLTVFQILTGEDWNEVMYHGMRAYE--NSPWYGV---VVIYFIFLFIC 675
Query: 1464 XXXXTLNLFIGVIIDNFNEQK 1484
LN+F+ + +DN NE +
Sbjct: 676 GNYILLNVFLAIAVDNLNEDE 696
Score = 77.8 bits (183), Expect = 3e-12
Identities = 46/176 (26%), Positives = 91/176 (51%), Gaps = 11/176 (6%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM--------PTTPTVESTE 170
+A +I N R ++ F ++ ILV+ IL+ P + +
Sbjct: 792 SAFFIFADTNKFRIFCHNVVCFSHFGNIVLVCILVSSILLAAEDPLHANSPRNRILNMFD 851
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA---L 227
FT ++T E +K+++ GF+L + R +N LD +V+ +A V+ + ++A L
Sbjct: 852 YFFTSVFTVEITLKMISYGFVLHEGAFCRSVFNLLDLIVVCVALVSFVLQNQTISAVKIL 911
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
R RVLR L+ + GLK +V +I ++K++ +++++T +FA++G+Q++ G
Sbjct: 912 RVLRVLRPLRAINRAKGLKHVVQCMIIAIKSIGNIVLVTFLLEFMFAVIGVQLFKG 967
Score = 68.9 bits (161), Expect = 1e-09
Identities = 49/164 (29%), Positives = 83/164 (50%), Gaps = 15/164 (9%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDH-Y--QQSETFSAVLDYLNMIFIVIFSSECLLKIF 1588
IV + F+ I+ I N L + +H Y + S + VL+ + + F++IF++E LKI
Sbjct: 73 IVDARPFEYFILATILCNCLALAFNHPYPGEDSNAVNQVLEKVELAFVIIFTTESALKII 132
Query: 1589 ALRY--H---YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLR 1643
A + H Y WN+ DF +V+ + S L E + LR RV R LR
Sbjct: 133 AYGFVLHQDAYLRNFWNVLDFSIVLIGLSSKAL----ENMNIDVKALRAFRVL---RPLR 185
Query: 1644 LVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
L+ G ++ +L ++ ++ L +I LL+ V+ ++AI G+ F
Sbjct: 186 LLSGLPSLQVVLNSIITAMVPLLHIALLVIFVIIVYAIVGLELF 229
Score = 62.9 bits (146), Expect = 9e-08
Identities = 43/146 (29%), Positives = 76/146 (52%), Gaps = 10/146 (6%)
Query: 784 FQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWP 843
F Y++ L F+ F + F+ + ++ LF+ N L+ LR+FKL + W
Sbjct: 517 FSDYISKL-FNRF-DFFVVIFSILELLFVKSGLLNPMGV--SVLRCARLLRIFKLTQYWE 572
Query: 844 TLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFT 903
+L L+ + +++ ++ +L +L I I I +++GMQLFG + F + PR NF
Sbjct: 573 SLRSLVGKLLKSVRSVASLLLLLSIFILICSLLGMQLFGGRF-----NFIAHEKPRANFD 627
Query: 904 DFMHSFMIVFRVLCGE-WIESMWDCM 928
+ + + VF++L GE W E M+ M
Sbjct: 628 GILQAMLTVFQILTGEDWNEVMYHGM 653
Score = 50.0 bits (114), Expect = 6e-04
Identities = 31/119 (26%), Positives = 64/119 (53%), Gaps = 10/119 (8%)
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIA-----LAYVTMGI-DLGNL 224
V+F ++T E +K+ A F Y+ +N DF V+ L +V G+ + +
Sbjct: 498 VVFVTLFTMEMVIKMGASXFS----DYISKLFNRFDFFVVIFSILELLFVKSGLLNPMGV 553
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
+ LR R+LR K L+++VG +++SV+++ +++L + + +L+G+Q++ G
Sbjct: 554 SVLRCARLLRIFKLTQYWESLRSLVGKLLKSVRSVASLLLLLSIFILICSLLGMQLFGG 612
Score = 48.0 bits (109), Expect = 0.003
Identities = 33/159 (20%), Positives = 78/159 (49%), Gaps = 18/159 (11%)
Query: 137 ILVHPLFSLFIITTILVNCILMIMP-------TTPTVESTEVIFTGIYTFESAVKVMARG 189
++V F + I I +N + +++ ++S FT ++T E +++ A
Sbjct: 1129 VVVSKRFEILIFIFIFINTVALMLKYDKQGKLEARILDSFNYFFTAVFTVEFILRLSAFS 1188
Query: 190 FILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAAL-------RTFRVLRALKTVAIV 242
F Y D N +DFV++ +Y+ + + +++ + R FRV+R +K ++
Sbjct: 1189 FR----HYFSDIGNVIDFVLVLGSYIDIIVTQSDISQVKFSVNFFRLFRVMRLIKLLSKE 1244
Query: 243 PGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
++ ++ I+S++ L V +L ++A++G+Q++
Sbjct: 1245 ESIRQLLWTFIKSIQALPYVALLIAMIFFIYAVIGMQLF 1283
Score = 47.2 bits (107), Expect = 0.005
Identities = 28/100 (28%), Positives = 55/100 (55%), Gaps = 6/100 (6%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
+R+ KL ++ L+ +++ AL + ++ +I FI+AV+GMQLFG+ ++ +
Sbjct: 1235 MRLIKLLSKEESIRQLLWTFIKSIQALPYVALLIAMIFFIYAVIGMQLFGQISIE-ENPL 1293
Query: 893 PDGDLPRW----NFTDFMHSFMIVFRVLCGE-WIESMWDC 927
+ + P NF +F ++ +++FR GE W + M C
Sbjct: 1294 EEEEWPTLHRNNNFQNFFYALLVLFRCATGESWQDIMMAC 1333
Score = 38.3 bits (85), Expect = 2.1
Identities = 19/77 (24%), Positives = 45/77 (58%), Gaps = 3/77 (3%)
Query: 805 IVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTF 864
+++ AL++ N+D KAL++ LR +L P+L ++++ + M L ++
Sbjct: 156 VLIGLSSKALENMNIDV---KALRAFRVLRPLRLLSGLPSLQVVLNSIITAMVPLLHIAL 212
Query: 865 VLCIIIFIFAVMGMQLF 881
++ +I ++A++G++LF
Sbjct: 213 LVIFVIIVYAIVGLELF 229
>UniRef50_Q4S9J4 Cluster: Chromosome undetermined SCAF14696, whole
genome shotgun sequence; n=4; Euteleostomi|Rep:
Chromosome undetermined SCAF14696, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 2188
Score = 286 bits (702), Expect = 4e-75
Identities = 177/622 (28%), Positives = 321/622 (51%), Gaps = 57/622 (9%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKW-- 1271
+I + F+ V+ I L+ + +ALE + + L + +FTVIF EM IK
Sbjct: 1161 VISHKLFDHVVLVFIFLNCITIALERPDIQANSTERVFLSVSNYVFTVIFLAEMAIKLPL 1220
Query: 1272 --------LALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGG---IQAFKTMR 1316
+ALGF Q Y ++W LD ++V VSL++ + +L GG + + +R
Sbjct: 1221 TPESLYKVVALGFCFGTQTYLQSSWNILDGLLVFVSLVDILVSLAYTGGNRILGILRVLR 1280
Query: 1317 TLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKC 1376
LR LRPLR +SR G+++VV L+ ++ I N++L+C F+++F I+GVQLF GK++ C
Sbjct: 1281 LLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVLICCAFFIVFGILGVQLFKGKFYHC 1340
Query: 1377 VDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAI 1436
++ +++ K+ C NY W NFD++ +A + LF ++ GW+ IM D +
Sbjct: 1341 EGLDTKNITN-----KSDCLQANYRWIRRKYNFDNLIQALMTLFVLSCKDGWVNIMYDGL 1395
Query: 1437 DSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMT 1496
D+ V +QP+R N +M LY LN+F+GV+++NF++ ++
Sbjct: 1396 DAVGVDQQPVRNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQDQEEEEARLRE 1455
Query: 1497 EDQKKYYNAMKKMGSKKPLKAIPRPRWRP----QAIVFEIVTDKKFDMIIMLFIGLNMLT 1552
E + K ++ +A RP + + + + T D+ I + I +N+ T
Sbjct: 1456 EKRLKMIEKKRRSKENGGSEAKQRPYYADYSPLRLSIHTLCTSHYLDLFITIIICINVFT 1515
Query: 1553 MTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR-YHYFVEPWNLFDFVVVMFSI 1611
M+++HY Q + VL Y N +F IF E LLK+ A +F + WN D +V SI
Sbjct: 1516 MSIEHYNQPQYLEEVLKYCNYVFTFIFVIEALLKLVAFGIQRFFKDRWNQLDIAIVALSI 1575
Query: 1612 LSLVLSD--IIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNIC 1669
+ + L + + ++PT++R++RV ++ RVL+L+K AKG+R LL + +LP + N+
Sbjct: 1576 MGITLEELKLSAALPINPTIIRIMRVLRIARVLKLLKMAKGMRALLDTVMQALPQVGNLG 1635
Query: 1670 LLLFLVMFIFAIFGMSFF----MHVKD-------KG-----------GLDDVYNFKTFVQ 1707
LL L+ FI+A G+ F + + D G GL F+ F
Sbjct: 1636 LLFMLLFFIYAALGVELFGKLALQLSDIYCLGCSDGWTECNDNNPCEGLSRHATFENFGM 1695
Query: 1708 SMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLI 1767
+ + LF++ST W+G++ + EC D + + + Y +++++++ +
Sbjct: 1696 AFLTLFRVSTGDNWNGIMKDTL--RECRPEDRQCLT----YLPWVSPIYFVTFVLMAQFV 1749
Query: 1768 VINMYIAVILENYSQATEDVQE 1789
++N+ +AV++++ ++ ++ +E
Sbjct: 1750 LVNVVVAVLMKHLEESNKEAKE 1771
Score = 118 bits (283), Expect = 2e-24
Identities = 82/304 (26%), Positives = 146/304 (48%), Gaps = 17/304 (5%)
Query: 1199 PFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRI 1258
P++ + LRL L + Y + + +I ++ +++E + P L+++L Y + +
Sbjct: 1480 PYYADYSPLRLSIHTLCTSHYLDLFITIIICINVFTMSIEHYNQPQ--YLEEVLKYCNYV 1537
Query: 1259 FTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAA---LCGAGGIQA--FK 1313
FT IF IE L+K +A G Q++F + W LD IV +S++ L A I +
Sbjct: 1538 FTFIFVIEALLKLVAFGIQRFFKDRWNQLDIAIVALSIMGITLEELKLSAALPINPTIIR 1597
Query: 1314 TMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
MR LR R L+ + +GMR +++ ++QA+P + N+ L+ ++ + I+A +GV+LF
Sbjct: 1598 IMRVLRIARVLKLLKMAKGMRALLDTVMQALPQVGNLGLLFMLLFFIYAALGVELFGKLA 1657
Query: 1374 FKCVDMNHTTLSHEIIP--DKNACT-LENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQ 1430
+ D+ S D N C L + F++ G A+L LF+V+T W
Sbjct: 1658 LQLSDIYCLGCSDGWTECNDNNPCEGLSRHA------TFENFGMAFLTLFRVSTGDNWNG 1711
Query: 1431 IMNDAI-DSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGG 1489
IM D + + R RQ + +Y +N+ + V++ + E K+A
Sbjct: 1712 IMKDTLRECRPEDRQCLTYLPWVSPIYFVTFVLMAQFVLVNVVVAVLMKHLEESNKEAKE 1771
Query: 1490 SLEM 1493
EM
Sbjct: 1772 DAEM 1775
Score = 100 bits (240), Expect = 3e-19
Identities = 71/266 (26%), Positives = 137/266 (51%), Gaps = 38/266 (14%)
Query: 177 YTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN--LAALRTFRVLR 234
+ E +K++A G I YL D WN LDFV++ + +D N L+A+RT RVLR
Sbjct: 54 FAVEMVIKMVALG-IFGSNCYLGDKWNQLDFVIVMAGVMEYSLDGHNASLSAIRTVRVLR 112
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKC----- 289
L+ + VP ++ +V +++++ L +V++L F +F ++G+Q++ G+L +C
Sbjct: 113 PLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLGED 172
Query: 290 ------VKVFP-----EDGSW-GNLTDENWERFCQNETNWYGEGG-DYPLCGNSSGAGQC 336
+ + P ED + + EN C ++ Y EGG + ++ C
Sbjct: 173 IRTTYNLSISPYYVTEEDSPFICSAPRENGMLRC-HDVPAYSEGGVECSATAGAASVNGC 231
Query: 337 ----EPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ----------- 381
+ +C QG NP+ G +FD G+A+++ F+++T + W ++
Sbjct: 232 VNWNQYYNICRQG-DYNPHKGAVNFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNF 290
Query: 382 LFFVVIIFLGSFYLVNLILAIVAMSY 407
++F+++I +GSF+++NL L ++A +
Sbjct: 291 IYFILLIIVGSFFMINLCLVVIATQF 316
Score = 92.7 bits (220), Expect = 9e-17
Identities = 59/160 (36%), Positives = 90/160 (56%), Gaps = 11/160 (6%)
Query: 1218 TYFETAVITMILLSSLALALEDVHLPHRPILQD---ILYYMDRIFTVIFFIEMLIKWLAL 1274
T+FE + +ILL+ + L + L D IL +D F +EM+IK +AL
Sbjct: 7 TWFEHISMLVILLNCVTLGMFQP-CEDISCLSDWCRILQVLDDCIFAFFAVEMVIKMVAL 65
Query: 1275 GF---QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQ 1331
G Y + W LDF+IVM ++ + +L G + +RT+R LRPLRA++R+
Sbjct: 66 GIFGSNCYLGDKWNQLDFVIVMAGVMEY--SLDGHNA--SLSAIRTVRVLRPLRAINRVP 121
Query: 1332 GMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
MR++V L+ +P + NVLL+C + IF I+GVQL+AG
Sbjct: 122 SMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAG 161
Score = 90.2 bits (214), Expect = 5e-16
Identities = 70/272 (25%), Positives = 133/272 (48%), Gaps = 34/272 (12%)
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSEC--LLKIF 1588
+IV K F+ IM+ I +N L+M +++++Q E + VL+ N++F +F E +L F
Sbjct: 648 KIVESKYFNRGIMIAILVNTLSMGIEYHEQPEELTDVLEISNIVFTSMFVLEMGFMLLAF 707
Query: 1589 ALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGA 1648
L + Y P+N+FD ++V+ S+ ++ S L V+R ++ RVL+LV+
Sbjct: 708 GL-FGYIRNPYNIFDSIIVIISVWEIIGQ--------SDGGLSVLRTFRLLRVLKLVRFL 758
Query: 1649 KGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF---MHVKDKGG--LDDVYNFK 1703
+R L L ++ + C+LL L +F F+I GM F + + G + D NF
Sbjct: 759 PALRRQLVVLMKTMDNVATFCMLLMLFIFTFSILGMHLFGCKFSFRTESGDTIPDRKNFD 818
Query: 1704 TFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVI 1763
+ + +++ +FQ+ T W+ VL G ++ Y ++ +
Sbjct: 819 SLLWAIVTVFQILTQEDWNVVLYN-----------------GMASTSPWAALYFVALMTF 861
Query: 1764 SFLIVINMYIAVILENYSQATEDVQEGLTDDD 1795
++ N+ +A+++E + QA D +DD+
Sbjct: 862 GNYVLFNLLVAILVEGF-QAEGDANRSESDDE 892
Score = 85.8 bits (203), Expect = 1e-14
Identities = 70/283 (24%), Positives = 132/283 (46%), Gaps = 40/283 (14%)
Query: 1201 WQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFT 1260
WQG+ R K K++E+ YF ++ IL+++L++ +E P L D+L + +FT
Sbjct: 639 WQGF---REKLKKIVESKYFNRGIMIAILVNTLSMGIEYHEQPEE--LTDVLEISNIVFT 693
Query: 1261 VIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRA 1320
+F +EM LA G Y N + D IIV++S+ + GG+ +T R LR
Sbjct: 694 SMFVLEMGFMLLAFGLFGYIRNPYNIFDSIIVIISVWEIIGQ--SDGGLSVLRTFRLLRV 751
Query: 1321 LRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMN 1380
L+ +R + ++ VV L++ + ++ ++ ++F F+I+G+ LF K+ +
Sbjct: 752 LKLVRFLPALRRQLVV---LMKTMDNVATFCMLLMLFIFTFSILGMHLFGCKF------S 802
Query: 1381 HTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSRE 1440
T S + IPD+ NFD + A + +FQ+ T + W ++ + + S
Sbjct: 803 FRTESGDTIPDRK--------------NFDSLLWAIVTVFQILTQEDWNVVLYNGMAS-- 846
Query: 1441 VGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQ 1483
T+ + LY NL + ++++ F +
Sbjct: 847 --------TSPWAALYFVALMTFGNYVLFNLLVAILVEGFQAE 881
Score = 75.8 bits (178), Expect = 1e-11
Identities = 58/194 (29%), Positives = 97/194 (50%), Gaps = 33/194 (17%)
Query: 122 WILDPFNPIRRVAIY---ILVHPLFSLFIITTILVNCILMIMPTTPTVE--STEVIFTGI 176
W L F+P + ++ ++ H LF ++ I +NCI + + P ++ STE +F +
Sbjct: 1143 WTLYLFSPDSQCRVWCQSVISHKLFDHVVLVFIFLNCITIAL-ERPDIQANSTERVFLSV 1201
Query: 177 --YTF----------------ESAVKVMARGFILQPFTYLRDAWNWLD----FV-----V 209
Y F ES KV+A GF TYL+ +WN LD FV +
Sbjct: 1202 SNYVFTVIFLAEMAIKLPLTPESLYKVVALGFCFGTQTYLQSSWNILDGLLVFVSLVDIL 1261
Query: 210 IALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFS 269
++LAY LG L LR R LR L+ ++ PGLK +V +I S++ + +++++
Sbjct: 1262 VSLAYTGGNRILGILRVLRLLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVLICCAF 1321
Query: 270 LSVFALMGLQIYMG 283
VF ++G+Q++ G
Sbjct: 1322 FIVFGILGVQLFKG 1335
Score = 66.1 bits (154), Expect = 9e-09
Identities = 32/120 (26%), Positives = 69/120 (57%), Gaps = 5/120 (4%)
Query: 163 TPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALA-YVTMGIDL 221
T +E + ++FT ++ E ++A G F Y+R+ +N D +++ ++ + +G
Sbjct: 682 TDVLEISNIVFTSMFVLEMGFMLLAFGL----FGYIRNPYNIFDSIIVIISVWEIIGQSD 737
Query: 222 GNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
G L+ LRTFR+LR LK V +P L+ + +++++ N+ +L M + F+++G+ ++
Sbjct: 738 GGLSVLRTFRLLRVLKLVRFLPALRRQLVVLMKTMDNVATFCMLLMLFIFTFSILGMHLF 797
Score = 63.7 bits (148), Expect = 5e-08
Identities = 50/160 (31%), Positives = 80/160 (50%), Gaps = 19/160 (11%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIV------IFSSECLLKIFALR 1591
F+ I ML I LN +T+ + +Q E S + D+ ++ ++ F+ E ++K+ AL
Sbjct: 9 FEHISMLVILLNCVTLGM--FQPCEDISCLSDWCRILQVLDDCIFAFFAVEMVIKMVALG 66
Query: 1592 YH----YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKG 1647
Y + WN DFV+VM ++ L + + S + +R VRV R LR +
Sbjct: 67 IFGSNCYLGDKWNQLDFVIVMAGVMEYSL----DGHNASLSAIRTVRVL---RPLRAINR 119
Query: 1648 AKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+R L+ L +LP L N+ LL F V FIF I G+ +
Sbjct: 120 VPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLW 159
Score = 51.6 bits (118), Expect = 2e-04
Identities = 44/201 (21%), Positives = 94/201 (46%), Gaps = 27/201 (13%)
Query: 127 FNPIRRVAIYILVHPLFSLFIITTILVNCILMIMP-------TTPTVESTEVIFTGIYTF 179
++P+R + LFI I +N M + ++ +FT I+
Sbjct: 1485 YSPLRLSIHTLCTSHYLDLFITIIICINVFTMSIEHYNQPQYLEEVLKYCNYVFTFIFVI 1544
Query: 180 ESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA-----------LR 228
E+ +K++A G +Q F +D WN LD ++AL+ + + ++ L+A +R
Sbjct: 1545 EALLKLVAFG--IQRF--FKDRWNQLDIAIVALSIMGITLEELKLSAALPINPTIIRIMR 1600
Query: 229 TFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQK 288
R+ R LK + + G++ ++ V++++ + ++ +L M ++A +G++++ G L +
Sbjct: 1601 VLRIARVLKLLKMAKGMRALLDTVMQALPQVGNLGLLFMLLFFIYAALGVELF-GKLALQ 1659
Query: 289 CVKVF---PEDGSWGNLTDEN 306
++ DG W D N
Sbjct: 1660 LSDIYCLGCSDG-WTECNDNN 1679
Score = 49.6 bits (113), Expect = 9e-04
Identities = 26/94 (27%), Positives = 45/94 (47%), Gaps = 10/94 (10%)
Query: 1393 NACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIY 1452
N C +Y +NFD++G A++ +FQV T +GW+ IM +D+ + Y
Sbjct: 239 NICRQGDYNPHKGAVNFDNIGYAWIAIFQVITLEGWVDIMYYVMDAH----------SFY 288
Query: 1453 MYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
++Y +NL + VI F+E K++
Sbjct: 289 NFIYFILLIIVGSFFMINLCLVVIATQFSETKQR 322
Score = 49.2 bits (112), Expect = 0.001
Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 7/96 (7%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY- 885
L++ LRV KL + P L + ++ +TM + +L + IF F+++GM LFG +
Sbjct: 743 LRTFRLLRVLKLVRFLPALRRQLVVLMKTMDNVATFCMLLMLFIFTFSILGMHLFGCKFS 802
Query: 886 --VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE 919
+ D PD R NF + + + VF++L E
Sbjct: 803 FRTESGDTIPD----RKNFDSLLWAIVTVFQILTQE 834
Score = 40.7 bits (91), Expect = 0.40
Identities = 19/77 (24%), Positives = 42/77 (54%), Gaps = 3/77 (3%)
Query: 805 IVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTF 864
++ + +LD HN A+++ LR + P++ +L++++ T+ LGN+
Sbjct: 86 VMAGVMEYSLDGHNASLS---AIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLL 142
Query: 865 VLCIIIFIFAVMGMQLF 881
+ + FIF ++G+QL+
Sbjct: 143 LCFFVFFIFGIVGVQLW 159
Score = 40.3 bits (90), Expect = 0.52
Identities = 52/222 (23%), Positives = 93/222 (41%), Gaps = 33/222 (14%)
Query: 726 IEQAGRQSRASE---LNVSVYYFPT---AEDDEDGPTFKEKLLDCLMKGIDFFCVWDCCW 779
+E+ Q+ ++E L+VS Y F AE P E L + G FC +
Sbjct: 1184 LERPDIQANSTERVFLSVSNYVFTVIFLAEMAIKLPLTPESLYKVVALG---FCFGTQTY 1240
Query: 780 LWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLA 839
L + LLVF V++ ++L + + + L+ LR ++
Sbjct: 1241 LQSSWNILDGLLVFVSLVDILVSLAYTGGNRILGIL---------RVLRLLRTLRPLRVI 1291
Query: 840 KSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF-GKNY----VDYVDRFPD 894
P L L++ + ++ +GN+ + C +F ++G+QLF GK Y +D +
Sbjct: 1292 SRAPGLKLVVETLITSLRPIGNIVLICCAFFIVFGILGVQLFKGKFYHCEGLDTKNITNK 1351
Query: 895 GDL----PRW-----NFTDFMHSFMIVFRVLCGE-WIESMWD 926
D RW NF + + + M +F + C + W+ M+D
Sbjct: 1352 SDCLQANYRWIRRKYNFDNLIQALMTLFVLSCKDGWVNIMYD 1393
Score = 39.5 bits (88), Expect = 0.91
Identities = 20/67 (29%), Positives = 35/67 (52%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
RV KL K + L+ + + + +GNL + ++ FI+A +G++LFGK + D +
Sbjct: 1606 RVLKLLKMAKGMRALLDTVMQALPQVGNLGLLFMLLFFIYAALGVELFGKLALQLSDIYC 1665
Query: 894 DGDLPRW 900
G W
Sbjct: 1666 LGCSDGW 1672
Score = 38.3 bits (85), Expect = 2.1
Identities = 14/41 (34%), Positives = 28/41 (68%)
Query: 796 FVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVF 836
+++LFIT+ I +N M+++H+N + +++ LK NY+ F
Sbjct: 1500 YLDLFITIIICINVFTMSIEHYNQPQYLEEVLKYCNYVFTF 1540
>UniRef50_A0C2L5 Cluster: Chromosome undetermined scaffold_145, whole
genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_145, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 2202
Score = 284 bits (697), Expect = 1e-74
Identities = 196/634 (30%), Positives = 324/634 (51%), Gaps = 46/634 (7%)
Query: 1212 FKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKW 1271
++++++T FE ++T+I L+S+ L L D ++P L+ D F ++F +E ++K
Sbjct: 1343 YRIVKDTKFEGFILTLIFLTSMKLVL-DTYIPSSGDLKFYSLQFDIGFAILFGLECILKI 1401
Query: 1272 LALGFQK----YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAM 1327
+A GF + Y +W LDF IV+ S FV + + K +R LR LRPLR +
Sbjct: 1402 VAFGFAQEEASYLRESWNVLDFFIVIAS---FVDVSVSSINLSFVKILRLLRTLRPLRFI 1458
Query: 1328 SRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHE 1387
+ + M+++V+AL+Q+I IFNV +V ++ WL+FAI+GV L K C ++ T +
Sbjct: 1459 THNKSMKILVSALLQSINGIFNVGIVIILSWLMFAILGVSLMKNKLHYCNLNDNQTYYY- 1517
Query: 1388 IIPDKNACTLENY--TWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQP 1445
K+ C + Y W+N +NFD+V + L LF ++T +GW M ID+ E G P
Sbjct: 1518 ---GKDDC-INKYQGVWDNRDINFDNVLQGMLTLFVLSTLEGWPDYMYYFIDADESG--P 1571
Query: 1446 IRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNA 1505
I + + Y +NLFIGVI+ N++ ++ S + +T+ Q + +
Sbjct: 1572 IFDAQLQFSWYFVIFILFGAMLLINLFIGVILVNYHLAEE---ASRDQNLTQTQSDWLDL 1628
Query: 1506 MKKMGSKKPLKAIPRPRWRP-QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETF 1564
K + P A+ P +A+ F+++ +K FD IM I N++TM L + S+ +
Sbjct: 1629 QKLIIHSNPNMAMFFPPDNSFRALFFKLIKNKYFDPFIMTIIVFNIITMGLAKEEASKQY 1688
Query: 1565 SAVLDYLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSLVL----SDI 1619
+L YLNM F +F E +LK+ AL Y WN FDF VV SIL LVL +
Sbjct: 1689 DQILSYLNMSFTFVFILEAILKLIALGIIGYMRNSWNQFDFFVVCASILDLVLDFSGNSF 1748
Query: 1620 IEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIF 1679
+ V P + RV RV +V R+ RLVK +G++ L+ SLPA+ N+ LLFLV FIF
Sbjct: 1749 VTFLKVGPQIARVFRVLRVTRLFRLVKQFQGLQKLIETALYSLPAMLNVTALLFLVFFIF 1808
Query: 1680 AIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDN 1739
+I G+ F +++ + + NF+ F S +LFQ S+ W ++
Sbjct: 1809 SILGVFLFQDIREGQVISESNNFQDFHHSFEILFQCSSGEDWHKIM----------FDTM 1858
Query: 1740 ERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENY--SQATEDVQEGLTDDDYD 1797
+ G NC + + +++I I++N++I +IL+ Y + D + +
Sbjct: 1859 KGGQEYNC-------VFFVLFIIIQQYIMLNLFILIILDQYEVNYFNSDNPLNKFQEFEN 1911
Query: 1798 MYYEIWQRFD-PDGSQYIRYDQLSDFLDVLEPPL 1830
++ E W +F D + L + + +E PL
Sbjct: 1912 IFVESWSKFAYQDKGMKMHGTSLVNLMFEMEQPL 1945
Score = 138 bits (335), Expect = 1e-30
Identities = 92/297 (30%), Positives = 155/297 (52%), Gaps = 43/297 (14%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEV------IFTGIYTFESAV 183
I +A I+ + +F + I I+ N +++ M T E T+ IF YT E+ +
Sbjct: 121 ISLIANKIVTNTIFEIITIFIIIFNSVMLAMDDPTTEEQTDFANLMDQIFLIYYTIEAIL 180
Query: 184 KVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLG--NLAALRTFRVLRALKTVAI 241
K++A+G I YLR+ WN LDF VI AY+ + NL +LR+FRVLR L+T++
Sbjct: 181 KIIAQGLIWPKKAYLRETWNILDFSVIITAYLPYFVSSNSLNLNSLRSFRVLRPLRTISS 240
Query: 242 VPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGN 301
+ L+ I+ A+ S+ LRD I+ +F ++FA+ G+Q++ G L ++C F + G
Sbjct: 241 IKSLRMILLALFASLAQLRDAAIVLIFFYTIFAIAGVQLFSGYLKRRC---FSDIGI-TL 296
Query: 302 LTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFG 361
+T + FC +++ DY LCG + NP +FDTFG
Sbjct: 297 MTSIEIDAFCSADSDC---PTDY-LCGKQTS----------------NPQNDLINFDTFG 336
Query: 362 WAFLSAFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
WAFL F + T + W + + +F++++ +G+F+LVNL LA++ +++
Sbjct: 337 WAFLQVFVITTLEGWAQIQEAVILTFSQFVIFYFLLVVIVGAFFLVNLTLAVIKLNF 393
Score = 105 bits (253), Expect = 9e-21
Identities = 74/241 (30%), Positives = 123/241 (51%), Gaps = 25/241 (10%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
K++ NT FE I +I+ +S+ LA++D P D MD+IF + + IE ++K +
Sbjct: 127 KIVTNTIFEIITIFIIIFNSVMLAMDD---PTTEEQTDFANLMDQIFLIYYTIEAILKII 183
Query: 1273 ALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMS 1328
A G + Y W LDF +++ + + + + ++R+ R LRPLR +S
Sbjct: 184 AQGLIWPKKAYLRETWNILDFSVIITAYLPYFVSSNSLN----LNSLRSFRVLRPLRTIS 239
Query: 1329 RMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK--CV-DMNHTTL- 1384
++ +R+++ AL ++ + + +V + F+ IFAI GVQLF+G Y K C D+ T +
Sbjct: 240 SIKSLRMILLALFASLAQLRDAAIVLIFFYTIFAIAGVQLFSG-YLKRRCFSDIGITLMT 298
Query: 1385 SHEI---------IPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDA 1435
S EI P C + +N +NFD G A+L +F + T +GW QI
Sbjct: 299 SIEIDAFCSADSDCPTDYLCGKQTSNPQNDLINFDTFGWAFLQVFVITTLEGWAQIQEAV 358
Query: 1436 I 1436
I
Sbjct: 359 I 359
Score = 94.7 bits (225), Expect = 2e-17
Identities = 73/272 (26%), Positives = 137/272 (50%), Gaps = 21/272 (7%)
Query: 1526 QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLL 1585
Q ++ +V F+ ++ L + LN L + LD E+ +A+L N F ++F+ E L
Sbjct: 1001 QRNLYHLVQSSYFEGMMNLAVALNTLILGLDGLISEES-NALLIQFNFTFTILFTIELGL 1059
Query: 1586 KIFAL-RYHYFVEPWNLFDFVVVMFSILSL-VLSDIIEKYFVSP-TLLRVVRVAKVGRVL 1642
K+ AL +Y + N+FD ++V S++ L +L K +S +R+ R +V RV
Sbjct: 1060 KLMALGAINYMKDTMNIFDALIVCLSLVELFILGGSNGKSSLSAFRAVRIFRAFRVLRVT 1119
Query: 1643 RLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNF 1702
+L+K + + L+ L+ S +L I LL+ + +FIF + GMSFF + NF
Sbjct: 1120 KLMKSLQFMGFLIKVLSNSFQSLMYILLLMIIFIFIFTLLGMSFFGGQLTYTPSRE--NF 1177
Query: 1703 KTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLV 1762
S +++FQ+ T W+ +L ++ + S I + YL+ +++
Sbjct: 1178 DNLQSSFLVVFQVLTLENWNSLLYELLLQPL---------------SPVITMIYLVLWIM 1222
Query: 1763 ISFLIVINMYIAVILENYSQATEDVQEGLTDD 1794
I + +N+++A++LEN+ + + + GL D
Sbjct: 1223 IGNYVFLNLFLAILLENFEEEYKVDKTGLESD 1254
Score = 93.9 bits (223), Expect = 4e-17
Identities = 53/190 (27%), Positives = 97/190 (51%), Gaps = 9/190 (4%)
Query: 1187 QKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRP 1246
QK + + + F+ + R FKLI+N YF+ ++T+I+ + + + L +
Sbjct: 1629 QKLIIHSNPNMAMFFPPDNSFRALFFKLIKNKYFDPFIMTIIVFNIITMGLAKEEASKQ- 1687
Query: 1247 ILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGA 1306
IL Y++ FT +F +E ++K +ALG Y N+W DF +V S+++ V G
Sbjct: 1688 -YDQILSYLNMSFTFVFILEAILKLIALGIIGYMRNSWNQFDFFVVCASILDLVLDFSGN 1746
Query: 1307 G-------GIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWL 1359
G Q + R LR R R + + QG++ ++ + ++P++ NV + + +
Sbjct: 1747 SFVTFLKVGPQIARVFRVLRVTRLFRLVKQFQGLQKLIETALYSLPAMLNVTALLFLVFF 1806
Query: 1360 IFAIMGVQLF 1369
IF+I+GV LF
Sbjct: 1807 IFSILGVFLF 1816
Score = 91.1 bits (216), Expect = 3e-16
Identities = 77/287 (26%), Positives = 134/287 (46%), Gaps = 45/287 (15%)
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTLDHY-QQSETFSAVLDYLNMIFIVIFSSECLLK 1586
I + IV D KF+ I+ I L + + LD Y S ++ F ++F EC+LK
Sbjct: 1341 IAYRIVKDTKFEGFILTLIFLTSMKLVLDTYIPSSGDLKFYSLQFDIGFAILFGLECILK 1400
Query: 1587 IFALRY-----HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRV 1641
I A + Y E WN+ DF +V+ S + + +S I + + ++++R+ + R
Sbjct: 1401 IVAFGFAQEEASYLRESWNVLDFFIVIASFVDVSVSSI------NLSFVKILRLLRTLRP 1454
Query: 1642 LRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSF------FMHVKDKG- 1694
LR + K ++ L+ AL S+ +FN+ +++ L +FAI G+S + ++ D
Sbjct: 1455 LRFITHNKSMKILVSALLQSINGIFNVGIVIILSWLMFAILGVSLMKNKLHYCNLNDNQT 1514
Query: 1695 ---GLDDVYN------------FKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDN 1739
G DD N F +Q M+ LF +ST GW + I+ +E
Sbjct: 1515 YYYGKDDCINKYQGVWDNRDINFDNVLQGMLTLFVLSTLEGWPDYMYYFIDADES----- 1569
Query: 1740 ERGSPGNCGSATIGIT-YLLSYLVISFLIVINMYIAVILENYSQATE 1785
G A + + Y + +++ +++IN++I VIL NY A E
Sbjct: 1570 -----GPIFDAQLQFSWYFVIFILFGAMLLINLFIGVILVNYHLAEE 1611
Score = 81.8 bits (193), Expect = 2e-13
Identities = 72/286 (25%), Positives = 133/286 (46%), Gaps = 43/286 (15%)
Query: 1212 FKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKW 1271
+ L++++YFE + + L++L L L+ + L L + FT++F IE+ +K
Sbjct: 1005 YHLVQSSYFEGMMNLAVALNTLILGLDGLISEESNAL---LIQFNFTFTILFTIELGLKL 1061
Query: 1272 LALGFQKYFTNAWCWLDFIIVMVSLINF--VAALCGAGGIQAFKTMRTLRALRPLRA--- 1326
+ALG Y + D +IV +SL+ + G + AF+ +R RA R LR
Sbjct: 1062 MALGAINYMKDTMNIFDALIVCLSLVELFILGGSNGKSSLSAFRAVRIFRAFRVLRVTKL 1121
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH 1386
M +Q M ++ L + S+ +LL+ +IF IF ++G+ F G+ + +T
Sbjct: 1122 MKSLQFMGFLIKVLSNSFQSLMYILLLMIIFIFIFTLLGMSFFGGQ------LTYT---- 1171
Query: 1387 EIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPI 1446
P + EN+ D++ ++L +FQV T + W ++ + + QP+
Sbjct: 1172 ---PSR-----ENF---------DNLQSSFLVVFQVLTLENWNSLLYELL------LQPL 1208
Query: 1447 RETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLE 1492
+ + +Y LNLF+ ++++NF E+ K LE
Sbjct: 1209 --SPVITMIYLVLWIMIGNYVFLNLFLAILLENFEEEYKVDKTGLE 1252
Score = 77.8 bits (183), Expect = 3e-12
Identities = 44/173 (25%), Positives = 96/173 (55%), Gaps = 11/173 (6%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT-TPTVEST-------E 170
++L+I N R++A I+ F FI+T I + + +++ T P+ +
Sbjct: 1327 SSLFIFSQQNQFRKIAYRIVKDTKFEGFILTLIFLTSMKLVLDTYIPSSGDLKFYSLQFD 1386
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTF 230
+ F ++ E +K++A GF + +YLR++WN LDF ++ ++V + + NL+ ++
Sbjct: 1387 IGFAILFGLECILKIVAFGFAQEEASYLRESWNVLDFFIVIASFVDVSVSSINLSFVKIL 1446
Query: 231 RVLRALKTVAIV---PGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
R+LR L+ + + +K +V A+++S+ + +V I+ + S +FA++G+ +
Sbjct: 1447 RLLRTLRPLRFITHNKSMKILVSALLQSINGIFNVGIVIILSWLMFAILGVSL 1499
Score = 65.3 bits (152), Expect = 2e-08
Identities = 50/167 (29%), Positives = 83/167 (49%), Gaps = 17/167 (10%)
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKI 1587
I +IVT+ F++I + I N + + +D +E + + ++ IF++ ++ E +LKI
Sbjct: 124 IANKIVTNTIFEIITIFIIIFNSVMLAMDD-PTTEEQTDFANLMDQIFLIYYTIEAILKI 182
Query: 1588 FAL-----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRV--VRVAKVGR 1640
A + Y E WN+ DF V++ + L YFVS L + +R +V R
Sbjct: 183 IAQGLIWPKKAYLRETWNILDFSVIITAYL---------PYFVSSNSLNLNSLRSFRVLR 233
Query: 1641 VLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
LR + K +R +L AL SL L + ++L IFAI G+ F
Sbjct: 234 PLRTISSIKSLRMILLALFASLAQLRDAAIVLIFFYTIFAIAGVQLF 280
Score = 54.4 bits (125), Expect = 3e-05
Identities = 38/114 (33%), Positives = 63/114 (55%), Gaps = 9/114 (7%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
R+F+L K + L LI ++ A+ N+T +L ++ FIF+++G+ LF V
Sbjct: 1769 RLFRLVKQFQGLQKLIETALYSLPAMLNVTALLFLVFFIFSILGVFLFQDIREGQVISES 1828
Query: 894 DGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVG-DVSCIPFFLATVVI 945
+ NF DF HSF I+F+ GE W + M+D M G + +C+ FF+ ++I
Sbjct: 1829 N------NFQDFHHSFEILFQCSSGEDWHKIMFDTMKGGQEYNCV-FFVLFIII 1875
Score = 53.6 bits (123), Expect = 5e-05
Identities = 45/189 (23%), Positives = 85/189 (44%), Gaps = 24/189 (12%)
Query: 116 SATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVI--- 172
S N P N R + ++ + F FI+T I+ N I M + + + I
Sbjct: 1635 SNPNMAMFFPPDNSFRALFFKLIKNKYFDPFIMTIIVFNIITMGLAKEEASKQYDQILSY 1694
Query: 173 ----FTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDL-GNL--- 224
FT ++ E+ +K++A G I Y+R++WN DF V+ + + + +D GN
Sbjct: 1695 LNMSFTFVFILEAILKLIALGII----GYMRNSWNQFDFFVVCASILDLVLDFSGNSFVT 1750
Query: 225 ------AALRTFRVLRALKTVAIV---PGLKTIVGAVIESVKNLRDVIILTMFSLSVFAL 275
R FRVLR + +V GL+ ++ + S+ + +V L +F++
Sbjct: 1751 FLKVGPQIARVFRVLRVTRLFRLVKQFQGLQKLIETALYSLPAMLNVTALLFLVFFIFSI 1810
Query: 276 MGLQIYMGV 284
+G+ ++ +
Sbjct: 1811 LGVFLFQDI 1819
Score = 49.6 bits (113), Expect = 9e-04
Identities = 32/98 (32%), Positives = 51/98 (52%), Gaps = 9/98 (9%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LRV KL KS + LI ++ + +L + ++ I IFIF ++GM FG + Y
Sbjct: 1116 LRVTKLMKSLQFMGFLIKVLSNSFQSLMYILLLMIIFIFIFTLLGMSFFG-GQLTYTP-- 1172
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCML 929
R NF + SF++VF+VL E W +++ +L
Sbjct: 1173 -----SRENFDNLQSSFLVVFQVLTLENWNSLLYELLL 1205
Score = 48.4 bits (110), Expect = 0.002
Identities = 35/125 (28%), Positives = 65/125 (52%), Gaps = 15/125 (12%)
Query: 173 FTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN-----LAAL 227
FT ++T E +K+MA G I Y++D N D +++ L+ V + I G+ L+A
Sbjct: 1049 FTILFTIELGLKLMALGAI----NYMKDTMNIFDALIVCLSLVELFILGGSNGKSSLSAF 1104
Query: 228 RT------FRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
R FRVLR K + + + ++ + S ++L +++L + + +F L+G+ +
Sbjct: 1105 RAVRIFRAFRVLRVTKLMKSLQFMGFLIKVLSNSFQSLMYILLLMIIFIFIFTLLGMSFF 1164
Query: 282 MGVLT 286
G LT
Sbjct: 1165 GGQLT 1169
>UniRef50_Q4RUD9 Cluster: Chromosome 1 SCAF14995, whole genome shotgun
sequence; n=3; cellular organisms|Rep: Chromosome 1
SCAF14995, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 2336
Score = 284 bits (696), Expect = 2e-74
Identities = 194/674 (28%), Positives = 342/674 (50%), Gaps = 56/674 (8%)
Query: 1219 YFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGF-- 1276
YFE +++ +I SS+ALA ED + +L Y D +FT +F EM+IK + G
Sbjct: 1123 YFEMSILLVIAASSIALAAEDP-VATSSDWNKVLRYFDYVFTGVFTFEMIIKMIDQGLIL 1181
Query: 1277 --QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMR 1334
YF + W LDFI+V+ +L+ F + I+ K++R LR LRPL+ + R+ ++
Sbjct: 1182 HDGSYFRDLWNILDFIVVVGALVAFALSNNKGRDIKTIKSLRVLRVLRPLKTIKRLPKLK 1241
Query: 1335 VVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTT----LSHEIIP 1390
V + +V ++ ++FN+L+V +F IFA++ VQLF GK+F C D + T + I
Sbjct: 1242 AVFDCVVTSLKNVFNILIVYKLFMFIFAVIAVQLFKGKFFYCTDSSKDTEKECQGYYIDY 1301
Query: 1391 DKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETN 1450
K+ ++ W ++D+V A L LF V++ +GW Q++ ++D E R P
Sbjct: 1302 GKDKKEMKRREWRRHEFHYDNVMWALLTLFTVSSGEGWPQVLQHSVDVTEEDRGPSHGNR 1361
Query: 1451 IYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMG 1510
+ M ++ +N+F+ +II F EQ K + +K +
Sbjct: 1362 MEMSIFYVIYFVVFPFFFVNIFVALIIITFQEQGDKMMEECSL-----EKNERACIDFAI 1416
Query: 1511 SKKPL-KAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLD 1569
S KPL + +P+ R Q ++ V F+ ++ I LN + + + +Y + AVL
Sbjct: 1417 SAKPLTRYMPQNRHTFQYRLWHFVVSPSFEYTVLAMIALNTIVLMMKYYSAPPAYEAVLK 1476
Query: 1570 YLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSLVLS-DIIEKYFVSP 1627
+LN F VIFS EC+LKI A + +YF + WN+FDF+ V+ SI +++ ++K+ +S
Sbjct: 1477 HLNTAFTVIFSVECILKIMAFGFLNYFRDTWNIFDFITVLGSITEIIVDLQSVDKFNMSF 1536
Query: 1628 TLL----RVVRVAKVGRVLRL-----VKGAKGIR--TLLFALAMSLPALF---------- 1666
L R++++ + G +R+ ++ K + LL A+ + A+
Sbjct: 1537 LKLFRAARLIKLLRQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYAIIGMQVRESNVA 1596
Query: 1667 -----NICLLLFLVMFIFA-IFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAG 1720
++ +L+ LV+F FA +FG + + DK ++ NFKTF +++LLF+ +T
Sbjct: 1597 SRNSADVEILIILVLFSFAQVFGN---IKLSDKTHINQHNNFKTFSGALLLLFRSATGES 1653
Query: 1721 WDGVLDGIINEEECDL-PDNERGSP-GNCGSATIGITYLLSYLVISFLIVINMYIAVILE 1778
W ++ + ++C+ P P G CGS Y +S++ S +++N+++AVI++
Sbjct: 1654 WQEIMLSCLGGQKCETDPAVPASDPEGGCGS-DFAYFYFVSFIFFSSFLMLNLFVAVIMD 1712
Query: 1779 NYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHK--PN 1836
N+ T D L D + IW +D I Y + + L + PPL + K P+
Sbjct: 1713 NFEYLTRD-SSILGPHHLDEFVRIWGEYDRAACGRIHYTDMYEMLTNMSPPLGLGKKCPS 1771
Query: 1837 K--YK-IISMDIPI 1847
K YK ++ M++P+
Sbjct: 1772 KLAYKRLVLMNMPV 1785
Score = 123 bits (297), Expect = 4e-26
Identities = 89/285 (31%), Positives = 149/285 (52%), Gaps = 50/285 (17%)
Query: 147 IITTILVNCILMIM----------PTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFT 196
I+TTI+ NCI++ + P + +E TE F G++ FE+ +K++A GF+ +
Sbjct: 2 ILTTIIANCIVLALEQHLPGEDKTPMSKRLEKTEPYFIGMFCFEAGIKIIALGFVFHKGS 61
Query: 197 YLRDAWNWLDFVVI-----ALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGA 251
YLR+ WN +DF+V+ A A M I + +L LR RVLR LK V+ +P L+ ++ +
Sbjct: 62 YLRNGWNVMDFIVVLSGILAAAGAHMNISV-DLRTLRAVRVLRPLKLVSGIPSLQIVLKS 120
Query: 252 VIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFC 311
+++++ L + +L F++ +FA++GL+ Y G L C E
Sbjct: 121 IMKAMVPLLQIGLLLFFAILMFAIIGLEFYSGRLHNTC---------------EARPGIL 165
Query: 312 QNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLM 371
+NET E ++P CG QC YVC + PN G T FD +A L+ F+ +
Sbjct: 166 ENETVDSSEL-EFP-CG----VRQCPARYVCRDTW-IGPNDGITQFDNILFAVLTVFQCI 218
Query: 372 TQDYWEN-LYQ-----------LFFVVIIFLGSFYLVNLILAIVA 404
T + W LY L+F+ +I +GSF+++NL+L +++
Sbjct: 219 TMEGWTTVLYNTDDALGPLWNWLYFIPLIIIGSFFVLNLVLGVLS 263
Score = 103 bits (247), Expect = 5e-20
Identities = 57/179 (31%), Positives = 100/179 (55%), Gaps = 14/179 (7%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM--PTTPTVESTEV----- 171
N+++I NP+RR Y++ F + I+ I + I + P + + +V
Sbjct: 1100 NSMFIFKHDNPVRRACHYVVNLRYFEMSILLVIAASSIALAAEDPVATSSDWNKVLRYFD 1159
Query: 172 -IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM------GIDLGNL 224
+FTG++TFE +K++ +G IL +Y RD WN LDF+V+ A V G D+ +
Sbjct: 1160 YVFTGVFTFEMIIKMIDQGLILHDGSYFRDLWNILDFIVVVGALVAFALSNNKGRDIKTI 1219
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
+LR RVLR LKT+ +P LK + V+ S+KN+ +++I+ + +FA++ +Q++ G
Sbjct: 1220 KSLRVLRVLRPLKTIKRLPKLKAVFDCVVTSLKNVFNILIVYKLFMFIFAVIAVQLFKG 1278
Score = 95.9 bits (228), Expect = 1e-17
Identities = 70/287 (24%), Positives = 130/287 (45%), Gaps = 15/287 (5%)
Query: 1206 TLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFI 1265
T + + + + + FE V+ MI L+++ L ++ P P + +L +++ FTVIF +
Sbjct: 1431 TFQYRLWHFVVSPSFEYTVLAMIALNTIVLMMKYYSAP--PAYEAVLKHLNTAFTVIFSV 1488
Query: 1266 EMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLR 1325
E ++K +A GF YF + W DFI V+ S+ + L ++ RA R ++
Sbjct: 1489 ECILKIMAFGFLNYFRDTWNIFDFITVLGSITEIIVDLQSVDKFN-MSFLKLFRAARLIK 1547
Query: 1326 AMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQL----FAGKYFKCVDMNH 1381
+ + +R+++ +Q+ ++ V L+ + + I+AI+G+Q+ A + V++
Sbjct: 1548 LLRQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYAIIGMQVRESNVASRNSADVEILI 1607
Query: 1382 TTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREV 1441
+ L + T N NF A L LF+ AT + W +IM + ++
Sbjct: 1608 ILVLFSFAQVFGNIKLSDKTHINQHNNFKTFSGALLLLFRSATGESWQEIMLSCLGGQKC 1667
Query: 1442 GRQPIRET--------NIYMYLYXXXXXXXXXXXTLNLFIGVIIDNF 1480
P + + Y Y LNLF+ VI+DNF
Sbjct: 1668 ETDPAVPASDPEGGCGSDFAYFYFVSFIFFSSFLMLNLFVAVIMDNF 1714
Score = 93.5 bits (222), Expect = 5e-17
Identities = 70/304 (23%), Positives = 138/304 (45%), Gaps = 33/304 (10%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
LR+ ++++ F V+ ++ L++L +A+ VH L LYY + +F +F E
Sbjct: 425 LRISIRRVVKTQTFYWTVLGLVALNTLCVAI--VHHNQPSWLSSFLYYAEFLFLALFLTE 482
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
M +K +LG + YF +++ D +++ S+ + G +R LR LR +
Sbjct: 483 MFLKMYSLGPRLYFHSSFNCFDCSVIVGSIFEVLWGFFRPGTSFGISVLRALRLLRIFKI 542
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH 1386
+R +V +L+ ++ SI +++ + +F ++FA++G+QLF G++
Sbjct: 543 TKYWASLRNLVVSLMNSMKSIISLIFLLFLFIVVFALLGMQLFGGRFI------------ 590
Query: 1387 EIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPI 1446
E+YT P NFD A + +FQ+ T + W ++M D I S Q
Sbjct: 591 ----------FEDYT----PTNFDTFPAAIMTVFQILTGEDWNEVMYDGIRS-----QGG 631
Query: 1447 RETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAM 1506
++ ++ +Y LN+F+ + +DN ++ E ++K
Sbjct: 632 VKSGMWSSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEEEAEAAFNEKHALQKA 691
Query: 1507 KKMG 1510
K++G
Sbjct: 692 KEVG 695
Score = 85.0 bits (201), Expect = 2e-14
Identities = 64/258 (24%), Positives = 123/258 (47%), Gaps = 23/258 (8%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR 1591
+V + F ++ + LN L + + H+ Q S+ L Y +F+ +F +E LK+++L
Sbjct: 432 VVKTQTFYWTVLGLVALNTLCVAIVHHNQPSWLSSFLYYAEFLFLALFLTEMFLKMYSLG 491
Query: 1592 YH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
YF +N FD V++ SI ++ ++LR +R+ R+ ++ K
Sbjct: 492 PRLYFHSSFNCFDCSVIVGSIFEVLWGFFRPGTSFGISVLRALRLL---RIFKITKYWAS 548
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDV--YNFKTFVQS 1708
+R L+ +L S+ ++ ++ LLFL + +FA+ GM F + +D NF TF +
Sbjct: 549 LRNLVVSLMNSMKSIISLIFLLFLFIVVFALLGMQLF---GGRFIFEDYTPTNFDTFPAA 605
Query: 1709 MILLFQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLI 1767
++ +FQ+ T W+ V+ DGI S G S Y + +
Sbjct: 606 IMTVFQILTGEDWNEVMYDGI-------------RSQGGVKSGMWSSIYFIVLTLFGNYT 652
Query: 1768 VINMYIAVILENYSQATE 1785
++N+++A+ ++N + A E
Sbjct: 653 LLNVFLAIAVDNLANAQE 670
Score = 81.8 bits (193), Expect = 2e-13
Identities = 68/283 (24%), Positives = 132/283 (46%), Gaps = 32/283 (11%)
Query: 1224 VITMILLSSLALALEDVHLP--HRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQ---- 1277
++T I+ + + LALE HLP + + L + F +F E IK +ALGF
Sbjct: 2 ILTTIIANCIVLALEQ-HLPGEDKTPMSKRLEKTEPYFIGMFCFEAGIKIIALGFVFHKG 60
Query: 1278 KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVV 1337
Y N W +DFI+V+ ++ A +T+R +R LRPL+ +S + +++V+
Sbjct: 61 SYLRNGWNVMDFIVVLSGILAAAGAHMNIS--VDLRTLRAVRVLRPLKLVSGIPSLQIVL 118
Query: 1338 NALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNA--- 1394
++++A+ + + L+ L+FAI+G++ ++G+ + L +E +
Sbjct: 119 KSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYSGRLHNTCEARPGILENETVDSSELEFP 178
Query: 1395 CTLENY--------TW---ENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGR 1443
C + TW + FD++ A L +FQ T +GW ++ + D+ +G
Sbjct: 179 CGVRQCPARYVCRDTWIGPNDGITQFDNILFAVLTVFQCITMEGWTTVLYNTDDA--LG- 235
Query: 1444 QPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
++ +LY LNL +GV+ F +++++
Sbjct: 236 ------PLWNWLYFIPLIIIGSFFVLNLVLGVLSGEFAKERER 272
Score = 71.3 bits (167), Expect = 2e-10
Identities = 47/162 (29%), Positives = 86/162 (53%), Gaps = 9/162 (5%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTL-DHYQQSETFSAVLDYLNMIFIVIFSSECLLKIF-- 1588
+V + F+M I+L I + + + D S ++ VL Y + +F +F+ E ++K+
Sbjct: 1118 VVNLRYFEMSILLVIAASSIALAAEDPVATSSDWNKVLRYFDYVFTGVFTFEMIIKMIDQ 1177
Query: 1589 ALRYH---YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLV 1645
L H YF + WN+ DF+VV+ ++++ LS+ + + LRV+RV R L+ +
Sbjct: 1178 GLILHDGSYFRDLWNILDFIVVVGALVAFALSNNKGRDIKTIKSLRVLRVL---RPLKTI 1234
Query: 1646 KGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
K ++ + + SL +FNI ++ L MFIFA+ + F
Sbjct: 1235 KRLPKLKAVFDCVVTSLKNVFNILIVYKLFMFIFAVIAVQLF 1276
Score = 66.9 bits (156), Expect = 5e-09
Identities = 40/102 (39%), Positives = 64/102 (62%), Gaps = 10/102 (9%)
Query: 827 LKSGNYLRVFKLAKSWPTL-NLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY 885
L++ LR+FK+ K W +L NL++S+M +M ++ +L F+L + I +FA++GMQLFG +
Sbjct: 531 LRALRLLRIFKITKYWASLRNLVVSLMN-SMKSIISLIFLLFLFIVVFALLGMQLFGGRF 589
Query: 886 VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWD 926
+ + D P NF F + M VF++L GE W E M+D
Sbjct: 590 I-FEDYTPT------NFDTFPAAIMTVFQILTGEDWNEVMYD 624
Score = 63.3 bits (147), Expect = 6e-08
Identities = 42/157 (26%), Positives = 78/157 (49%), Gaps = 16/157 (10%)
Query: 136 YILVHPLFSLFIITTILVNCILMIMP---TTPTVEST----EVIFTGIYTFESAVKVMAR 188
+ +V P F ++ I +N I+++M P E+ FT I++ E +K+MA
Sbjct: 1438 HFVVSPSFEYTVLAMIALNTIVLMMKYYSAPPAYEAVLKHLNTAFTVIFSVECILKIMAF 1497
Query: 189 GFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLG-----NLAALRTFRVLRALKTVAIVP 243
GF+ Y RD WN DF+ + + + +DL N++ L+ FR R +K +
Sbjct: 1498 GFL----NYFRDTWNIFDFITVLGSITEIIVDLQSVDKFNMSFLKLFRAARLIKLLRQGY 1553
Query: 244 GLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
++ ++ I+S K L V +L ++A++G+Q+
Sbjct: 1554 TIRILLWTFIQSFKALPYVCLLIAMLFFIYAIIGMQV 1590
Score = 59.7 bits (138), Expect = 8e-07
Identities = 46/155 (29%), Positives = 77/155 (49%), Gaps = 13/155 (8%)
Query: 1541 IIMLFIGLNMLTMTLDHYQQSET---FSAVLDYLNMIFIVIFSSECLLKIFALRY----- 1592
+I+ I N + + L+ + E S L+ FI +F E +KI AL +
Sbjct: 1 MILTTIIANCIVLALEQHLPGEDKTPMSKRLEKTEPYFIGMFCFEAGIKIIALGFVFHKG 60
Query: 1593 HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIR 1652
Y WN+ DF+VV+ IL+ + + +S L R +R +V R L+LV G ++
Sbjct: 61 SYLRNGWNVMDFIVVLSGILAAAGAHMN----ISVDL-RTLRAVRVLRPLKLVSGIPSLQ 115
Query: 1653 TLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+L ++ ++ L I LLLF + +FAI G+ F+
Sbjct: 116 IVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFY 150
Score = 45.2 bits (102), Expect = 0.018
Identities = 32/121 (26%), Positives = 58/121 (47%), Gaps = 12/121 (9%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIA-------LAYVTMGIDLG 222
E +F ++ E +K+ + G P Y ++N D VI + G G
Sbjct: 472 EFLFLALFLTEMFLKMYSLG----PRLYFHSSFNCFDCSVIVGSIFEVLWGFFRPGTSFG 527
Query: 223 NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYM 282
++ LR R+LR K L+ +V +++ S+K++ +I L + VFAL+G+Q++
Sbjct: 528 -ISVLRALRLLRIFKITKYWASLRNLVVSLMNSMKSIISLIFLLFLFIVVFALLGMQLFG 586
Query: 283 G 283
G
Sbjct: 587 G 587
>UniRef50_Q611Z7 Cluster: Putative uncharacterized protein CBG16834;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG16834 - Caenorhabditis
briggsae
Length = 1670
Score = 281 bits (688), Expect = 2e-73
Identities = 182/622 (29%), Positives = 321/622 (51%), Gaps = 60/622 (9%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
LR+K + + +F+ ++ I ++ + LA+E +P + L IFTVIF E
Sbjct: 1066 LRIKCLQTTQKKWFDYTILFFIGINCITLAMERPSIPPDSFERRFLQVSGYIFTVIFTGE 1125
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGG----IQAFKTMRTLRALR 1322
M++K + W LD I+V++SLIN L G + +R LRALR
Sbjct: 1126 MMMK-----------DGWNILDGILVVISLINVTFELLATGDSPKIFGVIRVLRLLRALR 1174
Query: 1323 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCV--DMN 1380
PLR ++R G+++VV L+ ++ I N++L+C F++IF I+GVQLF G + C+ ++
Sbjct: 1175 PLRVINRAPGVKLVVMTLISSLKPIGNIVLICCTFFIIFGILGVQLFKGMMYHCIGPEVG 1234
Query: 1381 HTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSRE 1440
+ T + + D W N NFD++G+A + LF +++ GW+ IM ID+
Sbjct: 1235 NVTTKVDCLED------TRNKWVNHRYNFDNLGQALMSLFVLSSKDGWVSIMYQGIDAVG 1288
Query: 1441 VGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQK 1500
V QPI N + +Y LN+F+GV+++NF+ K K EM E +K
Sbjct: 1289 VDVQPIENYNEWRMIYFISFLLLVGFFVLNMFVGVVVENFH--KCKEALEREMREKEKEK 1346
Query: 1501 KYYNAMKKM-------GSKK---------PLKAI-----PRPRW----RPQAIVFEIVTD 1535
+ +K+ G +K LK++ P + + + IVT
Sbjct: 1347 RLKRKLKRQKFEESMAGKRKKNRIVWVGTALKSVFSVERNYPYYHDYGHTRLFLHGIVTS 1406
Query: 1536 KKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY-HY 1594
K FD+ I IG+N+++M ++ Y VL LN F +F+ E +K+ AL + +
Sbjct: 1407 KYFDLAIAAVIGINVISMAMEFYMMPMGLKYVLKALNYFFTAVFTLEAAMKLIALGFKRF 1466
Query: 1595 FVEPWNLFDFVVVMFSILSLVLSDI-IEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRT 1653
F+E WN D +V+ SI ++ + + ++PT++RV+RV ++ RVL+L+K AKGIR+
Sbjct: 1467 FIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVLKLLKMAKGIRS 1526
Query: 1654 LLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDK-----GGLDDVYNFKTFVQS 1708
LL + +LP + N+ L FL+ FIFA G+ F ++ GL + +FK F +
Sbjct: 1527 LLDTVGEALPQVGNLGSLFFLLFFIFAALGVELFGKLECSEDHPCDGLGEHAHFKNFGMA 1586
Query: 1709 MILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIV 1768
+ LF+++T W+G++ + ++CD D+ C + + + +++IS ++
Sbjct: 1587 FLTLFRIATGDNWNGIMKDAL-RDDCDSSDH--CETNCCVDPILAPCFFVIFVLISQFVL 1643
Query: 1769 INMYIAVILENYSQATEDVQEG 1790
+N+ +AV++++ ++ + EG
Sbjct: 1644 VNVVVAVLMKHLEESNKRDAEG 1665
Score = 101 bits (242), Expect = 2e-19
Identities = 56/124 (45%), Positives = 76/124 (61%), Gaps = 4/124 (3%)
Query: 1251 ILYYMDRIFTVIFFIEMLIKWLALGF---QKYFTNAWCWLDFIIVMVSLINFVAALCGAG 1307
IL +D V F IEM+IK +ALGF Y ++ W LDF IVM + FV G
Sbjct: 144 ILDIIDNCIFVYFAIEMVIKIMALGFCGPAAYMSDTWNRLDFFIVMAGIAEFVLHEYLGG 203
Query: 1308 GIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQ 1367
I +RT+R LRPLRA++R+ MR++VN L+ +P + NVLL+C + IF I+GVQ
Sbjct: 204 NIN-LTAIRTVRVLRPLRAVNRIPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIVGVQ 262
Query: 1368 LFAG 1371
L+AG
Sbjct: 263 LWAG 266
Score = 94.3 bits (224), Expect = 3e-17
Identities = 67/242 (27%), Positives = 125/242 (51%), Gaps = 26/242 (10%)
Query: 1199 PFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRI 1258
P++ +G RL ++ + YF+ A+ +I ++ +++A+E +P L+ +L ++
Sbjct: 1388 PYYHDYGHTRLFLHGIVTSKYFDLAIAAVIGINVISMAMEFYMMPMG--LKYVLKALNYF 1445
Query: 1259 FTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFV----AALCGAGGIQAFKT 1314
FT +F +E +K +ALGF+++F W LD IV++S+ + AL +
Sbjct: 1446 FTAVFTLEAAMKLIALGFKRFFIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRV 1505
Query: 1315 MRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYF 1374
MR LR R L+ + +G+R +++ + +A+P + N+ + + + IFA +GV+LF GK
Sbjct: 1506 MRVLRIARVLKLLKMAKGIRSLLDTVGEALPQVGNLGSLFFLLFFIFAALGVELF-GK-L 1563
Query: 1375 KCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMND 1434
+C + D L + +F + G A+L LF++AT W IM D
Sbjct: 1564 ECSE------------DHPCDGLGEHA------HFKNFGMAFLTLFRIATGDNWNGIMKD 1605
Query: 1435 AI 1436
A+
Sbjct: 1606 AL 1607
Score = 91.1 bits (216), Expect = 3e-16
Identities = 56/184 (30%), Positives = 100/184 (54%), Gaps = 18/184 (9%)
Query: 129 PIRRVAIYILVHPLFSLFIITTILVNCILMIM-------PTTPTV--ESTEVIFTGIYTF 179
P R+ A+ +++ P F + IL+NC+ + M P T + ++I I+ +
Sbjct: 96 PPRKWALQMVMSPWFDRITMAVILINCVTLGMYRPCEDGPDCDTYRCQILDIIDNCIFVY 155
Query: 180 ---ESAVKVMARGFILQPFTYLRDAWNWLDFVVI--ALAYVTMGIDLG---NLAALRTFR 231
E +K+MA GF P Y+ D WN LDF ++ +A + LG NL A+RT R
Sbjct: 156 FAIEMVIKIMALGFC-GPAAYMSDTWNRLDFFIVMAGIAEFVLHEYLGGNINLTAIRTVR 214
Query: 232 VLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVK 291
VLR L+ V +P ++ +V +++++ L +V++L F +F ++G+Q++ G+L +CV
Sbjct: 215 VLRPLRAVNRIPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCVI 274
Query: 292 VFPE 295
P+
Sbjct: 275 NLPK 278
Score = 88.2 bits (209), Expect = 2e-15
Identities = 72/233 (30%), Positives = 119/233 (51%), Gaps = 23/233 (9%)
Query: 1503 YNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSE 1562
Y+ K +KP K RW + +V D F I++ I +N L+M ++++QQ E
Sbjct: 620 YDGEKAEKKRKPSKI----RWFRDKVRKFVVCDH-FTRGILVAILVNTLSMGVEYHQQPE 674
Query: 1563 TFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIE 1621
+ +L+Y N+ F +F+ E LLKI A + Y + +NLFD +V S+L L
Sbjct: 675 ILTVILEYSNLFFTALFALEMLLKIIASGFFGYLADGFNLFDGGIVALSVLEL------- 727
Query: 1622 KYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAI 1681
+ L V+R ++ R+L+LV+ +R L + ++ + LL L +FIF+I
Sbjct: 728 -FQEGKGGLSVLRTFRLLRILKLVRFMPALRYQLVVMLRTMDNVTVFFGLLVLFIFIFSI 786
Query: 1682 FGMSF----FMHVKDK--GGLD---DVYNFKTFVQSMILLFQMSTSAGWDGVL 1725
GM+ F V++K GGL + NF T + ++I +FQ+ T W+ VL
Sbjct: 787 LGMNLFGCKFCKVEEKFLGGLAKKCERKNFDTLLWALITVFQILTQEDWNMVL 839
Score = 85.4 bits (202), Expect = 1e-14
Identities = 76/285 (26%), Positives = 132/285 (46%), Gaps = 33/285 (11%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEM 1267
R K K + +F ++ IL+++L++ +E P IL IL Y + FT +F +EM
Sbjct: 638 RDKVRKFVVCDHFTRGILVAILVNTLSMGVEYHQQPE--ILTVILEYSNLFFTALFALEM 695
Query: 1268 LIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAM 1327
L+K +A GF Y + + D IV +S++ G GG+ +T R LR L+ +R M
Sbjct: 696 LLKIIASGFFGYLADGFNLFDGGIVALSVLELFQE--GKGGLSVLRTFRLLRILKLVRFM 753
Query: 1328 SRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHE 1387
++ VV+ + + ++F LLV IF IF+I+G+ LF K+ K
Sbjct: 754 PALRYQLVVMLRTMDNV-TVFFGLLVLFIF--IFSILGMNLFGCKFCK------------ 798
Query: 1388 IIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIR 1447
+ +K L + NFD + A + +FQ+ T + W ++ + +
Sbjct: 799 -VEEK---FLGGLAKKCERKNFDTLLWALITVFQILTQEDWNMVLFNG----------MA 844
Query: 1448 ETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLE 1492
+TN + LY NL + ++++ F E K++ LE
Sbjct: 845 QTNPWAALYFVALMTFGNYVLFNLLVAILVEGFQESKEEEKRQLE 889
Score = 79.4 bits (187), Expect = 9e-13
Identities = 71/289 (24%), Positives = 136/289 (47%), Gaps = 46/289 (15%)
Query: 1534 TDKK-FDMIIMLFIGLNMLTMTLDHYQ-QSETFSA-VLDYLNMIFIVIFSSECLLKIFAL 1590
T KK FD I+ FIG+N +T+ ++ ++F L IF VIF+ E ++K
Sbjct: 1074 TQKKWFDYTILFFIGINCITLAMERPSIPPDSFERRFLQVSGYIFTVIFTGEMMMK---- 1129
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTL---LRVVRVAKVGRVLRLVKG 1647
+ WN+ D ++V+ S++++ + SP + +RV+R+ + R LR++
Sbjct: 1130 ------DGWNILDGILVVISLINVTFELLATGD--SPKIFGVIRVLRLLRALRPLRVINR 1181
Query: 1648 AKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVK------DKGG------ 1695
A G++ ++ L SL + NI L+ IF I G+ F + + G
Sbjct: 1182 APGVKLVVMTLISSLKPIGNIVLICCTFFIIFGILGVQLFKGMMYHCIGPEVGNVTTKVD 1241
Query: 1696 -LDDV--------YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGN 1746
L+D YNF Q+++ LF +S+ GW ++ I+ D+ E +
Sbjct: 1242 CLEDTRNKWVNHRYNFDNLGQALMSLFVLSSKDGWVSIMYQGIDAVGVDVQPIENYNEWR 1301
Query: 1747 CGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDD 1795
+ Y +S+L++ V+NM++ V++EN+ + E ++ + + +
Sbjct: 1302 -------MIYFISFLLLVGFFVLNMFVGVVVENFHKCKEALEREMREKE 1343
Score = 72.9 bits (171), Expect = 8e-11
Identities = 60/208 (28%), Positives = 92/208 (44%), Gaps = 18/208 (8%)
Query: 1489 GSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGL 1548
G+ E ED Y + + +A P +W ++V FD I M I +
Sbjct: 66 GNEEQIEEEDSDLPYPGFAEPALRCFYQARPPRKW-----ALQMVMSPWFDRITMAVILI 120
Query: 1549 NMLTMTL----DHYQQSETFSA-VLDYLNMIFIVIFSSECLLKIFALRY----HYFVEPW 1599
N +T+ + + +T+ +LD ++ V F+ E ++KI AL + Y + W
Sbjct: 121 NCVTLGMYRPCEDGPDCDTYRCQILDIIDNCIFVYFAIEMVIKIMALGFCGPAAYMSDTW 180
Query: 1600 NLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALA 1659
N DF +VM I VL + Y L +R +V R LR V +R L+ L
Sbjct: 181 NRLDFFIVMAGIAEFVLHE----YLGGNINLTAIRTVRVLRPLRAVNRIPSMRILVNLLL 236
Query: 1660 MSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+LP L N+ LL F V FIF I G+ +
Sbjct: 237 DTLPMLGNVLLLCFFVFFIFGIVGVQLW 264
Score = 66.9 bits (156), Expect = 5e-09
Identities = 44/147 (29%), Positives = 81/147 (55%), Gaps = 12/147 (8%)
Query: 143 FSLFIITTILVNCILMIM-----PTTPTV--ESTEVIFTGIYTFESAVKVMARGFILQPF 195
F+ I+ ILVN + M + P TV E + + FT ++ E +K++A GF F
Sbjct: 650 FTRGILVAILVNTLSMGVEYHQQPEILTVILEYSNLFFTALFALEMLLKIIASGF----F 705
Query: 196 TYLRDAWNWLDFVVIALAYVTMGID-LGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIE 254
YL D +N D ++AL+ + + + G L+ LRTFR+LR LK V +P L+ + ++
Sbjct: 706 GYLADGFNLFDGGIVALSVLELFQEGKGGLSVLRTFRLLRILKLVRFMPALRYQLVVMLR 765
Query: 255 SVKNLRDVIILTMFSLSVFALMGLQIY 281
++ N+ L + + +F+++G+ ++
Sbjct: 766 TMDNVTVFFGLLVLFIFIFSILGMNLF 792
Score = 64.9 bits (151), Expect = 2e-08
Identities = 70/320 (21%), Positives = 135/320 (42%), Gaps = 39/320 (12%)
Query: 100 QTTFVVISKGKDIFRFSATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMI 159
Q TFV K +L+++ P NP+R + F I+ I +NCI +
Sbjct: 1036 QNTFVRKLLKKTCLHNRTEFSLFLMGPKNPLRIKCLQTTQKKWFDYTILFFIGINCITLA 1095
Query: 160 M--PTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM 217
M P+ P +S E F + + V+ G ++ ++D WN LD +++ ++ + +
Sbjct: 1096 MERPSIPP-DSFERRFLQVSGY--IFTVIFTGEMM-----MKDGWNILDGILVVISLINV 1147
Query: 218 GIDL----------GNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTM 267
+L G + LR R LR L+ + PG+K +V +I S+K + +++++
Sbjct: 1148 TFELLATGDSPKIFGVIRVLRLLRALRPLRVINRAPGVKLVVMTLISSLKPIGNIVLICC 1207
Query: 268 FSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLC 327
+F ++G+Q++ G++ C+ PE G+ D C +T Y
Sbjct: 1208 TFFIIFGILGVQLFKGMM-YHCIG--PEVGNVTTKVD------CLEDTRNKWVNHRY--- 1255
Query: 328 GNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQLFFVVI 387
N GQ L + Y D G + + + W +Y F+
Sbjct: 1256 -NFDNLGQALMSLFVLSSKDGWVSIMYQGIDAVG---VDVQPIENYNEWRMIY---FISF 1308
Query: 388 IFLGSFYLVNLILAIVAMSY 407
+ L F+++N+ + +V ++
Sbjct: 1309 LLLVGFFVLNMFVGVVVENF 1328
Score = 52.0 bits (119), Expect = 2e-04
Identities = 30/96 (31%), Positives = 50/96 (52%), Gaps = 3/96 (3%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L++ LR+ KL + P L + +M RTM + +L + IFIF+++GM LFG +
Sbjct: 738 LRTFRLLRILKLVRFMPALRYQLVVMLRTMDNVTVFFGLLVLFIFIFSILGMNLFGCKFC 797
Query: 887 DYVDRFPDG---DLPRWNFTDFMHSFMIVFRVLCGE 919
++F G R NF + + + VF++L E
Sbjct: 798 KVEEKFLGGLAKKCERKNFDTLLWALITVFQILTQE 833
Score = 51.2 bits (117), Expect = 3e-04
Identities = 34/136 (25%), Positives = 69/136 (50%), Gaps = 6/136 (4%)
Query: 797 VELFITLCIVVNTLFMALDHHNM--DKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGR 854
+++FI + + +F + + + + + ++ RV KL K + L+ +G
Sbjct: 1474 LDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVLKLLKMAKGIRSLLDTVGE 1533
Query: 855 TMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP-DGDLPRWNFTDFMHSFMIVF 913
+ +GNL + ++ FIFA +G++LFGK ++ + P DG +F +F +F+ +F
Sbjct: 1534 ALPQVGNLGSLFFLLFFIFAALGVELFGK--LECSEDHPCDGLGEHAHFKNFGMAFLTLF 1591
Query: 914 RVLCGE-WIESMWDCM 928
R+ G+ W M D +
Sbjct: 1592 RIATGDNWNGIMKDAL 1607
Score = 49.2 bits (112), Expect = 0.001
Identities = 47/181 (25%), Positives = 85/181 (46%), Gaps = 30/181 (16%)
Query: 137 ILVHPLFSLFIITTILVNCILMIMP--TTP-----TVESTEVIFTGIYTFESAVKVMARG 189
I+ F L I I +N I M M P +++ FT ++T E+A+K++A G
Sbjct: 1403 IVTSKYFDLAIAAVIGINVISMAMEFYMMPMGLKYVLKALNYFFTAVFTLEAAMKLIALG 1462
Query: 190 FILQPFTYLRDAWNWLDFVVIALAY----------VTMGIDLGNLAALRTFRVLRALKTV 239
F + + WN LD ++ L+ + + I+ + +R R+ R LK +
Sbjct: 1463 F----KRFFIEKWNRLDMFIVILSIAGIIFEEFEALELPINPTIIRVMRVLRIARVLKLL 1518
Query: 240 AIVPGLKTI---VGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPED 296
+ G++++ VG + V NL + L F +FA +G++++ G L +C + P D
Sbjct: 1519 KMAKGIRSLLDTVGEALPQVGNLGSLFFLLFF---IFAALGVELF-GKL--ECSEDHPCD 1572
Query: 297 G 297
G
Sbjct: 1573 G 1573
Score = 43.6 bits (98), Expect = 0.056
Identities = 25/95 (26%), Positives = 48/95 (50%), Gaps = 11/95 (11%)
Query: 324 YPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ-- 381
Y C SS P + Q NP G SFD G+A+++ F +++ + W ++
Sbjct: 354 YNECQVSSPPLYIFPILIIAQVMQRNPFQGSVSFDNIGFAWVAIFLVISLEGWTDIMYYV 413
Query: 382 ---------LFFVVIIFLGSFYLVNLILAIVAMSY 407
++FV++I +G+F+++NL L ++A +
Sbjct: 414 QDAHSFWNWIYFVLLIVIGAFFMINLCLVVIATQF 448
Score = 38.3 bits (85), Expect = 2.1
Identities = 15/56 (26%), Positives = 34/56 (60%)
Query: 826 ALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
A+++ LR + P++ +L++++ T+ LGN+ + + FIF ++G+QL+
Sbjct: 209 AIRTVRVLRPLRAVNRIPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLW 264
Score = 37.1 bits (82), Expect = 4.9
Identities = 18/63 (28%), Positives = 35/63 (55%), Gaps = 11/63 (17%)
Query: 356 SFDTFGWAFLSAFRLMTQDYWENLY-----------QLFFVVIIFLGSFYLVNLILAIVA 404
+FDT WA ++ F+++TQ+ W + L+FV ++ G++ L NL++AI+
Sbjct: 815 NFDTLLWALITVFQILTQEDWNMVLFNGMAQTNPWAALYFVALMTFGNYVLFNLLVAILV 874
Query: 405 MSY 407
+
Sbjct: 875 EGF 877
>UniRef50_A0CTH2 Cluster: Chromosome undetermined scaffold_27, whole
genome shotgun sequence; n=4; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_27, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 2357
Score = 279 bits (684), Expect = 6e-73
Identities = 193/603 (32%), Positives = 301/603 (49%), Gaps = 40/603 (6%)
Query: 1212 FKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKW 1271
++++++ FET + MI L+S L D ++P L++ +D F V F +EM++K
Sbjct: 1422 YRIVKDDKFETLIFFMIFLTSTKLVF-DTYIPDTGKLKETSLQIDIFFAVFFGVEMIMKI 1480
Query: 1272 LALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAM 1327
+A GF Y +W LDF IV+ S I+ + + K +R LR LRPLR +
Sbjct: 1481 IAFGFVQQESSYLRESWNILDFFIVIASFIDVSVSTINLSFV---KILRLLRTLRPLRFI 1537
Query: 1328 SRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHE 1387
+ + M+++V+AL+Q+I IFNV +V ++ W++FAI+G+ L K C D + +
Sbjct: 1538 THNRSMKILVSALLQSINGIFNVAIVVILVWMMFAILGINLEKNKMHYC-DTGDDEIWYH 1596
Query: 1388 IIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIR 1447
PD+ C W N +NFD++ L LF ++T +GW M ID+ E G PI+
Sbjct: 1597 YGPDE--CAKHGGVWANRKVNFDNILNGMLTLFILSTLEGWPDQMYWFIDADESG--PIK 1652
Query: 1448 ETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMK 1507
+ Y +NLFIGVI+ N++ ++ S + +T+ Q + K
Sbjct: 1653 GAQLQFSWYFIVFILIGSILLMNLFIGVILVNYHLAEE---ASRDKILTQPQVDWIELQK 1709
Query: 1508 KMGSKKPLKAIPRPRWRP-QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSA 1566
+ P A+ P +A VF I+ + FD I++ I N++TM L +
Sbjct: 1710 LIVHANPNLAMFFSPENPFRAKVFIIIKHRYFDPTILMIIVCNIVTMGLSQDDSPIAYDN 1769
Query: 1567 VLDYLNMIFIVIFSSECLLKIFALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFV 1625
L LN F +F +E LLKI AL Y WN FDF VV SIL LVL F+
Sbjct: 1770 ALQSLNTAFTFVFITEALLKIIALGPVGYMRNSWNQFDFFVVCASILDLVLQ-FTGNSFI 1828
Query: 1626 SPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMS 1685
S + RV+RV R+ RL+K +G++ L+ SLPA+ N+ LLFLV FIF+I G+
Sbjct: 1829 SFLIFRVLRVT---RLFRLIKSFEGLQKLIETAIYSLPAMLNVTALLFLVFFIFSILGVF 1885
Query: 1686 FFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPG 1745
F ++ +DDV NF F S LLF+ ST W V+ I ++ G
Sbjct: 1886 LFGSIRSGWAIDDVNNFSDFHHSFELLFRCSTGEDWYKVMFDITMQD---------GQGY 1936
Query: 1746 NCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTD-DDYD-MYYEIW 1803
C + + ++VI I++N++I +IL+ Y + L +Y+ M+ E W
Sbjct: 1937 YC-------IFFIIFIVIQQYIMLNLFILIILDQYEINYFNSDNPLNKFQEYENMFIESW 1989
Query: 1804 QRF 1806
+F
Sbjct: 1990 SKF 1992
Score = 154 bits (374), Expect = 2e-35
Identities = 97/291 (33%), Positives = 158/291 (54%), Gaps = 38/291 (13%)
Query: 137 ILVHPLFSLFIITTILVNCILMIM--PTTPTVES----TEVIFTGIYTFESAVKVMARGF 190
I HPLF L + I+ N ++ + PTT S T++IF YT E+ +K++A GF
Sbjct: 146 ITTHPLFELMTLLMIIFNSAMLAIDDPTTNVQTSFQDLTDIIFLAYYTAEAVLKIVALGF 205
Query: 191 ILQPFTYLRDAWNWLDFVVIALAYVTMGIDLG--NLAALRTFRVLRALKTVAIVPGLKTI 248
IL YL+D WN LDF VI AY+ + NL ALR+FRVLR L+TV+ + L+TI
Sbjct: 206 ILPKKAYLKDTWNILDFSVIVTAYIPYFLSSNSVNLNALRSFRVLRPLRTVSSIKALRTI 265
Query: 249 VGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWE 308
+ A+ S+ LRD +++ +F S+FA+ G+ ++ G L ++C+ +W ++DE
Sbjct: 266 LLALFASIAQLRDAVVVLIFFYSIFAIAGVSLFSGYLKRRCIGEM-SGITW--ISDE--I 320
Query: 309 RFCQNETNW-YGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSA 367
FC ++ N + E Y ++C + NP +FDTFG++FL
Sbjct: 321 LFCADDNNCPFPEDTIY------------NENFICGKQIA-NPQNDLVNFDTFGYSFLQV 367
Query: 368 FRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
F + T + W + L+F++++ +G+F+LVNL LAI+ +++
Sbjct: 368 FIITTLEGWTQIQTAVMLTFSQYVVLYFIIVVIVGAFFLVNLTLAIIKLNF 418
Score = 96.3 bits (229), Expect = 8e-18
Identities = 74/243 (30%), Positives = 125/243 (51%), Gaps = 32/243 (13%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
K+ + FE + MI+ +S LA++D + QD+ D IF + E ++K +
Sbjct: 145 KITTHPLFELMTLLMIIFNSAMLAIDDPTTNVQTSFQDLT---DIIFLAYYTAEAVLKIV 201
Query: 1273 ALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMS 1328
ALGF + Y + W LDF +++ + I + + +R+ R LRPLR +S
Sbjct: 202 ALGFILPKKAYLKDTWNILDFSVIVTAYIPYFLSSNSVN----LNALRSFRVLRPLRTVS 257
Query: 1329 RMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK--CV-DMNHTT-L 1384
++ +R ++ AL +I + + ++V + F+ IFAI GV LF+G Y K C+ +M+ T +
Sbjct: 258 SIKALRTILLALFASIAQLRDAVVVLIFFYSIFAIAGVSLFSG-YLKRRCIGEMSGITWI 316
Query: 1385 SHEII--PDKNAC-----TLENYTW---------ENSPMNFDHVGKAYLCLFQVATFKGW 1428
S EI+ D N C T+ N + +N +NFD G ++L +F + T +GW
Sbjct: 317 SDEILFCADDNNCPFPEDTIYNENFICGKQIANPQNDLVNFDTFGYSFLQVFIITTLEGW 376
Query: 1429 IQI 1431
QI
Sbjct: 377 TQI 379
Score = 88.6 bits (210), Expect = 2e-15
Identities = 52/184 (28%), Positives = 93/184 (50%), Gaps = 5/184 (2%)
Query: 1187 QKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRP 1246
QK A + + F+ R K F +I++ YF+ ++ +I+ + + + L P
Sbjct: 1708 QKLIVHANPNLAMFFSPENPFRAKVFIIIKHRYFDPTILMIIVCNIVTMGLSQ---DDSP 1764
Query: 1247 ILQD-ILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCG 1305
I D L ++ FT +F E L+K +ALG Y N+W DF +V S+++ V G
Sbjct: 1765 IAYDNALQSLNTAFTFVFITEALLKIIALGPVGYMRNSWNQFDFFVVCASILDLVLQFTG 1824
Query: 1306 AGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMG 1365
I +F R LR R R + +G++ ++ + ++P++ NV + + + IF+I+G
Sbjct: 1825 NSFI-SFLIFRVLRVTRLFRLIKSFEGLQKLIETAIYSLPAMLNVTALLFLVFFIFSILG 1883
Query: 1366 VQLF 1369
V LF
Sbjct: 1884 VFLF 1887
Score = 88.2 bits (209), Expect = 2e-15
Identities = 74/287 (25%), Positives = 132/287 (45%), Gaps = 45/287 (15%)
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTLDHY-QQSETFSAVLDYLNMIFIVIFSSECLLK 1586
I + IV D KF+ +I I L + D Y + +++ F V F E ++K
Sbjct: 1420 ICYRIVKDDKFETLIFFMIFLTSTKLVFDTYIPDTGKLKETSLQIDIFFAVFFGVEMIMK 1479
Query: 1587 IFALRY-----HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRV 1641
I A + Y E WN+ DF +V+ S + + +S I + + ++++R+ + R
Sbjct: 1480 IIAFGFVQQESSYLRESWNILDFFIVIASFIDVSVSTI------NLSFVKILRLLRTLRP 1533
Query: 1642 LRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSF---FMHVKDKG---- 1694
LR + + ++ L+ AL S+ +FN+ +++ LV +FAI G++ MH D G
Sbjct: 1534 LRFITHNRSMKILVSALLQSINGIFNVAIVVILVWMMFAILGINLEKNKMHYCDTGDDEI 1593
Query: 1695 ----GLDDV-----------YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDN 1739
G D+ NF + M+ LF +ST GW + I+ +E
Sbjct: 1594 WYHYGPDECAKHGGVWANRKVNFDNILNGMLTLFILSTLEGWPDQMYWFIDADE------ 1647
Query: 1740 ERGSPGNCGSATIGIT-YLLSYLVISFLIVINMYIAVILENYSQATE 1785
G A + + Y + +++I ++++N++I VIL NY A E
Sbjct: 1648 ----SGPIKGAQLQFSWYFIVFILIGSILLMNLFIGVILVNYHLAEE 1690
Score = 81.0 bits (191), Expect = 3e-13
Identities = 63/258 (24%), Positives = 125/258 (48%), Gaps = 22/258 (8%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR-YHYFV 1596
F+ + L + LN + + LD + + L N+ F ++F+ E LK+ + +Y
Sbjct: 1098 FEAAMNLAVALNTVILALDGLLPDSSANT-LQQFNLGFTILFTIELGLKVIGMGPKNYIS 1156
Query: 1597 EPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLF 1656
+ N+FD V+V S++ L S + R VR+ + RVLR+ K + ++ + F
Sbjct: 1157 DTMNVFDAVIVALSLVELFFLGGGTSGKSSLSAFRSVRIFRAFRVLRVTKLMRSLQFMGF 1216
Query: 1657 ---ALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLF 1713
L + + I +LL L +FIF + GM+FF K Y+ + +++F
Sbjct: 1217 LIKVLGNAFQSFMYIMVLLLLFIFIFTLLGMAFFGGQLSKTPSRQSYD--DIQSAFLVVF 1274
Query: 1714 QMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYI 1773
Q+ T W+ +L ++ ++ SA I + YL+ +++I + +N+++
Sbjct: 1275 QVLTLENWNSILWDLLIQDV---------------SAFITVPYLVFWIMIGNYVFLNLFL 1319
Query: 1774 AVILENYSQATEDVQEGL 1791
A++LEN+ + ++ + GL
Sbjct: 1320 AILLENFEEEYKNDKAGL 1337
Score = 78.2 bits (184), Expect = 2e-12
Identities = 41/172 (23%), Positives = 92/172 (53%), Gaps = 11/172 (6%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMI----MPTTPTVEST----EV 171
+L++ N +RR+ I+ F I I + ++ +P T ++ T ++
Sbjct: 1407 SLYLFSQENIVRRICYRIVKDDKFETLIFFMIFLTSTKLVFDTYIPDTGKLKETSLQIDI 1466
Query: 172 IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFR 231
F + E +K++A GF+ Q +YLR++WN LDF ++ +++ + + NL+ ++ R
Sbjct: 1467 FFAVFFGVEMIMKIIAFGFVQQESSYLRESWNILDFFIVIASFIDVSVSTINLSFVKILR 1526
Query: 232 VLRALKTVAIVP---GLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
+LR L+ + + +K +V A+++S+ + +V I+ + +FA++G+ +
Sbjct: 1527 LLRTLRPLRFITHNRSMKILVSALLQSINGIFNVAIVVILVWMMFAILGINL 1578
Score = 74.1 bits (174), Expect = 3e-11
Identities = 51/193 (26%), Positives = 96/193 (49%), Gaps = 10/193 (5%)
Query: 1215 IENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLAL 1274
+++ YFE A+ + L+++ LAL+ + LP + L + FT++F IE+ +K + +
Sbjct: 1093 VQSGYFEAAMNLAVALNTVILALDGL-LPDSSA--NTLQQFNLGFTILFTIELGLKVIGM 1149
Query: 1275 GFQKYFTNAWCWLDFIIVMVSLINFV---AALCGAGGIQAFKTMRTLRALRPLRA---MS 1328
G + Y ++ D +IV +SL+ G + AF+++R RA R LR M
Sbjct: 1150 GPKNYISDTMNVFDAVIVALSLVELFFLGGGTSGKSSLSAFRSVRIFRAFRVLRVTKLMR 1209
Query: 1329 RMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD-MNHTTLSHE 1387
+Q M ++ L A S ++++ L+F IF ++G+ F G+ K ++ +
Sbjct: 1210 SLQFMGFLIKVLGNAFQSFMYIMVLLLLFIFIFTLLGMAFFGGQLSKTPSRQSYDDIQSA 1269
Query: 1388 IIPDKNACTLENY 1400
+ TLEN+
Sbjct: 1270 FLVVFQVLTLENW 1282
Score = 67.3 bits (157), Expect = 4e-09
Identities = 47/162 (29%), Positives = 81/162 (50%), Gaps = 13/162 (8%)
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL 1590
+I T F+++ +L I N + +D + ++ D ++IF+ +++E +LKI AL
Sbjct: 145 KITTHPLFELMTLLMIIFNSAMLAIDD-PTTNVQTSFQDLTDIIFLAYYTAEAVLKIVAL 203
Query: 1591 RY-----HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLV 1645
+ Y + WN+ DF V++ + + LS + L +R +V R LR V
Sbjct: 204 GFILPKKAYLKDTWNILDFSVIVTAYIPYFLSS-------NSVNLNALRSFRVLRPLRTV 256
Query: 1646 KGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
K +RT+L AL S+ L + ++L IFAI G+S F
Sbjct: 257 SSIKALRTILLALFASIAQLRDAVVVLIFFYSIFAIAGVSLF 298
Score = 59.7 bits (138), Expect = 8e-07
Identities = 41/175 (23%), Positives = 78/175 (44%), Gaps = 16/175 (9%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPT-------VESTEV 171
N P NP R I+ H F I+ I+ N + M + + ++S
Sbjct: 1717 NLAMFFSPENPFRAKVFIIIKHRYFDPTILMIIVCNIVTMGLSQDDSPIAYDNALQSLNT 1776
Query: 172 IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDL-GN----LAA 226
FT ++ E+ +K++A G P Y+R++WN DF V+ + + + + GN
Sbjct: 1777 AFTFVFITEALLKIIALG----PVGYMRNSWNQFDFFVVCASILDLVLQFTGNSFISFLI 1832
Query: 227 LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
R RV R + + GL+ ++ I S+ + +V L +F+++G+ ++
Sbjct: 1833 FRVLRVTRLFRLIKSFEGLQKLIETAIYSLPAMLNVTALLFLVFFIFSILGVFLF 1887
Score = 56.8 bits (131), Expect = 6e-06
Identities = 40/114 (35%), Positives = 63/114 (55%), Gaps = 8/114 (7%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
R+F+L KS+ L LI ++ A+ N+T +L ++ FIF+++G+ LFG +
Sbjct: 1840 RLFRLIKSFEGLQKLIETAIYSLPAMLNVTALLFLVFFIFSILGVFLFGSIRSGWA--ID 1897
Query: 894 DGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWD-CMLVGDVSCIPFFLATVVI 945
D + NF+DF HSF ++FR GE W + M+D M G FF+ +VI
Sbjct: 1898 DVN----NFSDFHHSFELLFRCSTGEDWYKVMFDITMQDGQGYYCIFFIIFIVI 1947
Score = 55.2 bits (127), Expect = 2e-05
Identities = 36/117 (30%), Positives = 62/117 (52%), Gaps = 13/117 (11%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LRV KL +S + LI ++G + + +L + IFIF ++GM FG + +
Sbjct: 1202 LRVTKLMRSLQFMGFLIKVLGNAFQSFMYIMVLLLLFIFIFTLLGMAFFG----GQLSKT 1257
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSC---IPFFLATVVI 945
P R ++ D +F++VF+VL E W +WD +L+ DVS +P+ + ++I
Sbjct: 1258 PS----RQSYDDIQSAFLVVFQVLTLENWNSILWD-LLIQDVSAFITVPYLVFWIMI 1309
Score = 44.4 bits (100), Expect = 0.032
Identities = 38/151 (25%), Positives = 75/151 (49%), Gaps = 16/151 (10%)
Query: 149 TTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFV 208
T IL L+ + T++ + FT ++T E +KV+ G P Y+ D N D V
Sbjct: 1110 TVILALDGLLPDSSANTLQQFNLGFTILFTIELGLKVIGMG----PKNYISDTMNVFDAV 1165
Query: 209 VIALAYVTM----GIDLG--NLAALRT------FRVLRALKTVAIVPGLKTIVGAVIESV 256
++AL+ V + G G +L+A R+ FRVLR K + + + ++ + +
Sbjct: 1166 IVALSLVELFFLGGGTSGKSSLSAFRSVRIFRAFRVLRVTKLMRSLQFMGFLIKVLGNAF 1225
Query: 257 KNLRDVIILTMFSLSVFALMGLQIYMGVLTQ 287
++ +++L + + +F L+G+ + G L++
Sbjct: 1226 QSFMYIMVLLLLFIFIFTLLGMAFFGGQLSK 1256
>UniRef50_A0CTU2 Cluster: Chromosome undetermined scaffold_27, whole
genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_27, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 2076
Score = 277 bits (678), Expect = 3e-72
Identities = 197/637 (30%), Positives = 324/637 (50%), Gaps = 49/637 (7%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+R +K+++N+ F+ ++ I LSSL L ++ + + L + D F + F +E
Sbjct: 1235 IRRLCYKIVKNSLFDQIILFAIFLSSLKLVIDTY-------VSNFLDWADWFFALFFGVE 1287
Query: 1267 MLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALR 1322
L K +A GF Y +W LDFIIV+ S I+ A + K +R LR LR
Sbjct: 1288 FLFKIIAYGFVMEENAYLRESWNILDFIIVVCSFIDISVASIDLSFV---KILRLLRTLR 1344
Query: 1323 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHT 1382
PLR +S+ + M+++V L+ +I I NV +V ++ +L+FAI+GV L GK C D+
Sbjct: 1345 PLRLISQNKSMKLLVTTLINSISGIVNVGVVVILVFLMFAILGVNLEKGKMNYC-DIGSD 1403
Query: 1383 TLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVG 1442
S+ K C E Y W+N MNFD+V A L LF V+T +GW M +D+ E G
Sbjct: 1404 EQSYL---HKADCISEGYEWKNRDMNFDNVFWAMLTLFIVSTQEGWPTQMYWFVDADESG 1460
Query: 1443 RQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKY 1502
PI+ ++ Y +N+F+GVI+ N+ K + ++ DQ+ +
Sbjct: 1461 --PIKNNQMWFTSYFLIFLLIGSILLMNMFVGVILVNY---KLAEDEMKDKNVSRDQEDW 1515
Query: 1503 YNAMKKMGSKKPLKAIPRP-RWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQS 1561
+ K + P A+ P + + +A++F+I+++K FD IML I +N+ M ++ S
Sbjct: 1516 ISIQKLIVDSNPNFALYYPPKNQYRALIFKIISNKIFDFFIMLCIIVNIAAMASNYEGSS 1575
Query: 1562 ETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDII 1620
+ +L+ LN++ VIF E LLKI YF WN FDF VV+ SIL ++LS
Sbjct: 1576 VKYQYILETLNLVLSVIFIFESLLKIIGFGPRGYFRNNWNQFDFFVVLSSILDMILSFTD 1635
Query: 1621 EK----YFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVM 1676
K P L+RV RV +V R+ RLVK ++ L+ SLPALFN+ L+FL+
Sbjct: 1636 NKDNPILSAGPQLIRVFRVLRVTRLFRLVKSLHSLKKLIDTALFSLPALFNVSALMFLLY 1695
Query: 1677 FIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDL 1736
FIF++ G+ F ++ D ++ NF F ++ILLF+ +T W ++ ++N
Sbjct: 1696 FIFSVLGVFLFSNLSDGYIINSENNFNDFHHALILLFRCTTGEDWYLLMYDVMN------ 1749
Query: 1737 PDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLT--DD 1794
+ S C +Y + ++VI I++N+++ +IL+ Y + + L +
Sbjct: 1750 ----KASYYYC-------SYFIIFVVIMQRIMLNLFVLIILDQYERFYFNSDNPLQRFQE 1798
Query: 1795 DYDMYYEIWQRFDPD-GSQYIRYDQLSDFLDVLEPPL 1830
D + + W + Q I DQL + ++ P+
Sbjct: 1799 FEDDFVDGWAPLASETKGQQIHQDQLVQLMLSIKAPM 1835
Score = 152 bits (369), Expect = 8e-35
Identities = 99/304 (32%), Positives = 156/304 (51%), Gaps = 44/304 (14%)
Query: 123 ILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM--PTT----PTVESTEVIFTGI 176
IL I +A+ + HP+F F + I+ N I++ + PTT P + ++IF +
Sbjct: 82 ILIQAKKISMMAMQLTKHPIFEFFTLLVIIFNSIMLALDDPTTDIQTPFQDLMDIIFLAV 141
Query: 177 YTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLG--NLAALRTFRVLR 234
YTFE+ +K++A GF+ TYLRD WN LDF VI AY+ ++ L+ALR+ RVLR
Sbjct: 142 YTFEAVLKIIAMGFVFNSNTYLRDLWNVLDFTVIVTAYIPYFVNNSGLQLSALRSLRVLR 201
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFP 294
L+T++ V L++I+ + S L + +I+ F+ ++FA+ GLQ++ G +C F
Sbjct: 202 PLRTISSVKSLRSIMMTLFASFAELGNSLIILGFTYTIFAIAGLQLFSGYAKLRC---FD 258
Query: 295 EDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGY 354
E+G G D P C G C Y+C + NP G
Sbjct: 259 ENGI----------------IQMSGYDTDEPFCN-----GSCPENYICGK-MMDNPINGL 296
Query: 355 TSFDTFGWAFLSAFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLILAIV 403
SFD FG AFL F + T + W + Q +F++ + +G+F+LVNL LAI+
Sbjct: 297 LSFDDFGLAFLQVFIITTLEGWTTIMQTIMTTFSQFSVFYFLLCVIIGAFFLVNLTLAII 356
Query: 404 AMSY 407
+++
Sbjct: 357 KINF 360
Score = 99 bits (238), Expect = 6e-19
Identities = 71/241 (29%), Positives = 121/241 (50%), Gaps = 22/241 (9%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+ + +L ++ FE + +I+ +S+ LAL+D + QD+ MD IF ++ E
Sbjct: 89 ISMMAMQLTKHPIFEFFTLLVIIFNSIMLALDDPTTDIQTPFQDL---MDIIFLAVYTFE 145
Query: 1267 MLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALR 1322
++K +A+GF Y + W LDF +++ + I + G+Q +R+LR LR
Sbjct: 146 AVLKIIAMGFVFNSNTYLRDLWNVLDFTVIVTAYIPYFV---NNSGLQ-LSALRSLRVLR 201
Query: 1323 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG-KYFKCVDMNH 1381
PLR +S ++ +R ++ L + + N L++ + IFAI G+QLF+G +C D N
Sbjct: 202 PLRTISSVKSLRSIMMTLFASFAELGNSLIILGFTYTIFAIAGLQLFSGYAKLRCFDENG 261
Query: 1382 TTLSHEIIPDKNACT---LENY---TWENSPMN----FDHVGKAYLCLFQVATFKGWIQI 1431
D+ C ENY ++P+N FD G A+L +F + T +GW I
Sbjct: 262 IIQMSGYDTDEPFCNGSCPENYICGKMMDNPINGLLSFDDFGLAFLQVFIITTLEGWTTI 321
Query: 1432 M 1432
M
Sbjct: 322 M 322
Score = 84.6 bits (200), Expect = 2e-14
Identities = 65/253 (25%), Positives = 127/253 (50%), Gaps = 25/253 (9%)
Query: 1529 VFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIF 1588
+F IV + F+M++ L + +N + + LD + S L+ N+ F ++F+ E LK+
Sbjct: 923 LFLIVDSRYFNMMLNLAVFINTVILCLDGLVNN---SEDLNDFNLAFTILFTIEMGLKMI 979
Query: 1589 ALRY-HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKG 1647
Y +P N+FD ++V S++ + F S +R+ R +V RV +L++
Sbjct: 980 GFGIIQYIRDPMNIFDALIVALSLIDIFFLSG-SSVFKS---VRIFRAFRVLRVTKLMRS 1035
Query: 1648 AKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQ 1707
K + L+ L+ + +L I LLL L ++IF + GMSFF Y+ TF +
Sbjct: 1036 LKFMNFLVQVLSNAFQSLMYIFLLLILFIYIFTLLGMSFFGGQLTYTPSRQSYD--TFYE 1093
Query: 1708 SMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLI 1767
S +++FQ+ T W+ +L ++ + S I + YL++++ I +
Sbjct: 1094 SFLVVFQVLTLENWNSILYDLLKQPV---------------SWIITMIYLIAWIFIGSYV 1138
Query: 1768 VINMYIAVILENY 1780
++N+++A +L+ +
Sbjct: 1139 LLNLFLASLLDQF 1151
Score = 84.6 bits (200), Expect = 2e-14
Identities = 45/169 (26%), Positives = 93/169 (55%), Gaps = 5/169 (2%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPT--VESTEVIFTGIY 177
+L I NPIRR+ I+ + LF I+ I ++ + +++ T + ++ + F +
Sbjct: 1225 SLNIFSQNNPIRRLCYKIVKNSLFDQIILFAIFLSSLKLVIDTYVSNFLDWADWFFALFF 1284
Query: 178 TFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM---GIDLGNLAALRTFRVLR 234
E K++A GF+++ YLR++WN LDF+++ +++ + IDL + LR R LR
Sbjct: 1285 GVEFLFKIIAYGFVMEENAYLRESWNILDFIIVVCSFIDISVASIDLSFVKILRLLRTLR 1344
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
L+ ++ +K +V +I S+ + +V ++ + +FA++G+ + G
Sbjct: 1345 PLRLISQNKSMKLLVTTLINSISGIVNVGVVVILVFLMFAILGVNLEKG 1393
Score = 73.3 bits (172), Expect = 6e-11
Identities = 48/195 (24%), Positives = 96/195 (49%), Gaps = 7/195 (3%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
L+ K F ++++ YF + + ++++ L L+ + + + L D + FT++F IE
Sbjct: 919 LQFKLFLIVDSRYFNMMLNLAVFINTVILCLDGL-VNNSEDLNDF----NLAFTILFTIE 973
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
M +K + G +Y + D +IV +SLI+ + L G+ ++ + R R LR +
Sbjct: 974 MGLKMIGFGIIQYIRDPMNIFDALIVALSLID-IFFLSGSSVFKSVRIFRAFRVLRVTKL 1032
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKCVDMNHTTLS 1385
M ++ M +V L A S+ + L+ ++F IF ++G+ F G+ + ++ T
Sbjct: 1033 MRSLKFMNFLVQVLSNAFQSLMYIFLLLILFIYIFTLLGMSFFGGQLTYTPSRQSYDTFY 1092
Query: 1386 HEIIPDKNACTLENY 1400
+ TLEN+
Sbjct: 1093 ESFLVVFQVLTLENW 1107
Score = 59.7 bits (138), Expect = 8e-07
Identities = 40/155 (25%), Positives = 76/155 (49%), Gaps = 13/155 (8%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY----- 1592
F+ +L I N + + LD ++ + D +++IF+ +++ E +LKI A+ +
Sbjct: 102 FEFFTLLVIIFNSIMLALDD-PTTDIQTPFQDLMDIIFLAVYTFEAVLKIIAMGFVFNSN 160
Query: 1593 HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIR 1652
Y + WN+ DF V++ + + +++ S L +R +V R LR + K +R
Sbjct: 161 TYLRDLWNVLDFTVIVTAYIPYFVNN-------SGLQLSALRSLRVLRPLRTISSVKSLR 213
Query: 1653 TLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+++ L S L N ++L IFAI G+ F
Sbjct: 214 SIMMTLFASFAELGNSLIILGFTYTIFAIAGLQLF 248
Score = 54.8 bits (126), Expect = 2e-05
Identities = 37/148 (25%), Positives = 75/148 (50%), Gaps = 11/148 (7%)
Query: 144 SLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWN 203
++FI T IL C+ ++ + + + FT ++T E +K++ G I Y+RD N
Sbjct: 939 AVFINTVIL--CLDGLVNNSEDLNDFNLAFTILFTIEMGLKMIGFGII----QYIRDPMN 992
Query: 204 WLDFVVIALAYVTMGIDLGN-----LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKN 258
D +++AL+ + + G+ + R FRVLR K + + + +V + + ++
Sbjct: 993 IFDALIVALSLIDIFFLSGSSVFKSVRIFRAFRVLRVTKLMRSLKFMNFLVQVLSNAFQS 1052
Query: 259 LRDVIILTMFSLSVFALMGLQIYMGVLT 286
L + +L + + +F L+G+ + G LT
Sbjct: 1053 LMYIFLLLILFIYIFTLLGMSFFGGQLT 1080
Score = 54.8 bits (126), Expect = 2e-05
Identities = 36/113 (31%), Positives = 59/113 (52%), Gaps = 7/113 (6%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
R+F+L KS +L LI ++ AL N++ ++ ++ FIF+V+G+ LF Y+
Sbjct: 1659 RLFRLVKSLHSLKKLIDTALFSLPALFNVSALMFLLYFIFSVLGVFLFSNLSDGYIINSE 1718
Query: 894 DGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSCIPFFLATVVI 945
+ NF DF H+ +++FR GE W M+D M +F+ VVI
Sbjct: 1719 N------NFNDFHHALILLFRCTTGEDWYLLMYDVMNKASYYYCSYFIIFVVI 1765
Score = 49.6 bits (113), Expect = 9e-04
Identities = 44/176 (25%), Positives = 82/176 (46%), Gaps = 24/176 (13%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMI-------MPTTPTVESTEVIFTGIYT 178
P N R + I+ + +F FI+ I+VN M + +E+ ++ + I+
Sbjct: 1535 PKNQYRALIFKIISNKIFDFFIMLCIIVNIAAMASNYEGSSVKYQYILETLNLVLSVIFI 1594
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN------LAA----LR 228
FES +K++ G P Y R+ WN DF V+ + + M + + L+A +R
Sbjct: 1595 FESLLKIIGFG----PRGYFRNNWNQFDFFVVLSSILDMILSFTDNKDNPILSAGPQLIR 1650
Query: 229 TFRVLRALKTVAIVP---GLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
FRVLR + +V LK ++ + S+ L +V L +F+++G+ ++
Sbjct: 1651 VFRVLRVTRLFRLVKSLHSLKKLIDTALFSLPALFNVSALMFLLYFIFSVLGVFLF 1706
Score = 47.2 bits (107), Expect = 0.005
Identities = 29/97 (29%), Positives = 50/97 (51%), Gaps = 9/97 (9%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LRV KL +S +N L+ ++ +L + +L + I+IF ++GM FG + Y
Sbjct: 1027 LRVTKLMRSLKFMNFLVQVLSNAFQSLMYIFLLLILFIYIFTLLGMSFFG-GQLTYTPS- 1084
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
R ++ F SF++VF+VL E W ++D +
Sbjct: 1085 ------RQSYDTFYESFLVVFQVLTLENWNSILYDLL 1115
>UniRef50_Q23FG9 Cluster: Cation channel family protein; n=1;
Tetrahymena thermophila SB210|Rep: Cation channel family
protein - Tetrahymena thermophila SB210
Length = 3301
Score = 264 bits (648), Expect = 1e-68
Identities = 162/526 (30%), Positives = 275/526 (52%), Gaps = 25/526 (4%)
Query: 1206 TLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFI 1265
++R+ +K++++ FE ++ I+ SSL L + D ++ + L +D +F IF
Sbjct: 2272 SIRILFYKIVKHPQFENLILFFIVTSSLKLVV-DTYVDEHSDVGIALKNVDLMFNFIFIA 2330
Query: 1266 EMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRAL 1321
E +K ++ GF Y +W +DF IV S+I+ + + K +R LR L
Sbjct: 2331 EATLKIISFGFIGDENSYLDESWSQIDFFIVCTSIIDMTFS---GVNVSFIKILRLLRTL 2387
Query: 1322 RPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNH 1381
RPLR +S M+VVV AL ++I IFN+L+V + W++FAI+G+ L + C +++
Sbjct: 2388 RPLRFISHNVNMKVVVIALFESISGIFNILIVIFLIWIMFAILGISLIGNRMGYCSGISY 2447
Query: 1382 TTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREV 1441
+ + D+ N + N + + + K +V GW +M AIDS
Sbjct: 2448 I---YHVNQDR-----VNSIFSNLSILTNEIPKQSSA--KVWDTNGWPDLMYQAIDSNTA 2497
Query: 1442 GRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKK 1501
P+++ I + + +NLF+GVI NFNE +K S +F+TE+QK+
Sbjct: 2498 DVGPVKDNYIQISYFYMIFILVGSFFLINLFVGVIFLNFNEAQKNERQS-SLFLTEEQKR 2556
Query: 1502 YYNAMKKM-GSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQ 1560
+ + + G K P + +++ IVT++KF++ IM+ I N+LTM + +
Sbjct: 2557 WIEFQQMIIGVKAEFAQSVVPTQKIPKLMYNIVTNQKFEIFIMVLIVCNILTMAMAYEGS 2616
Query: 1561 SETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVL--S 1617
++ ++L+ +N+ F F E ++K A +F WN FD VV+ SI+ ++L S
Sbjct: 2617 PSSYDSILENINLFFTSCFILETIMKFIAFGIKGFFANDWNKFDLFVVVSSIVDIILNYS 2676
Query: 1618 DIIEKYF--VSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLV 1675
+ F + P L+R++RV +V R+L+LVK KG++ L+ L SLP+L N+ LL LV
Sbjct: 2677 GALSASFLRIGPQLIRIIRVFRVSRLLKLVKSMKGLQKLIETLMFSLPSLINVGALLLLV 2736
Query: 1676 MFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGW 1721
FI++I G+ F V + +D NF+ F +MI LF+ ST W
Sbjct: 2737 FFIYSILGVFMFKDVTEGVVIDKYNNFENFGNAMITLFRCSTGENW 2782
Score = 131 bits (316), Expect = 2e-28
Identities = 94/285 (32%), Positives = 153/285 (53%), Gaps = 48/285 (16%)
Query: 143 FSLFIITTILVNCILMIM--PTTPTVES----TEVIFTGIYTFESAVKVMARGFILQPFT 196
F I+ I+ N I++++ PTT S E F YT E+ +K++A GFIL
Sbjct: 523 FENTILLIIIFNSIMLMLDDPTTDVQSSFADWCEQFFLWAYTVEACLKIIALGFILPQGA 582
Query: 197 YLRDAWNWLDFVVI--ALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIE 254
YL+D WN LDF ++ +L + +G NL ALR+ R+LR L+T++ V LK ++ +
Sbjct: 583 YLKDGWNILDFAIVVSSLLPLVIGSSTVNLRALRSLRILRPLRTISKVKKLKILLKTLFS 642
Query: 255 SVKNL-RDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQN 313
++ L +IILT F L +FA+ GLQ++ G+L ++C+ D G + D N
Sbjct: 643 AIPYLVNSMIILTFFFL-IFAIGGLQLFGGLLLRRCL-----DPLSGIVADYN------- 689
Query: 314 ETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQ 373
+CG G QC+ Y+C + NP + T+FD ++FL F+++T
Sbjct: 690 -----------QVCG---GGYQCDDIYICGKTMS-NPQFNVTNFDDIFYSFLMVFQVITL 734
Query: 374 DYW-ENLYQLF----------FVVIIFLGSFYLVNLILAIVAMSY 407
+ W + +YQLF FV+++F+GSF+L+NL LA++ +
Sbjct: 735 EGWTQIMYQLFDAFSVFTVIYFVLLVFIGSFFLINLTLAVIKAKF 779
Score = 113 bits (271), Expect = 6e-23
Identities = 73/243 (30%), Positives = 126/243 (51%), Gaps = 20/243 (8%)
Query: 1212 FKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKW 1271
+K+I++ +FE ++ +I+ +S+ L L+D P + + ++ F + +E +K
Sbjct: 515 YKIIKSNWFENTILLIIIFNSIMLMLDD---PTTDVQSSFADWCEQFFLWAYTVEACLKI 571
Query: 1272 LALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAM 1327
+ALGF Y + W LDF IV+ SL+ V G+ + + +R+LR LRPLR +
Sbjct: 572 IALGFILPQGAYLKDGWNILDFAIVVSSLLPLVI---GSSTVN-LRALRSLRILRPLRTI 627
Query: 1328 SRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYF-KCV--------D 1378
S+++ +++++ L AIP + N +++ F+LIFAI G+QLF G +C+ D
Sbjct: 628 SKVKKLKILLKTLFSAIPYLVNSMIILTFFFLIFAIGGLQLFGGLLLRRCLDPLSGIVAD 687
Query: 1379 MNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDS 1438
N D C + + NFD + ++L +FQV T +GW QIM D+
Sbjct: 688 YNQVCGGGYQCDDIYICGKTMSNPQFNVTNFDDIFYSFLMVFQVITLEGWTQIMYQLFDA 747
Query: 1439 REV 1441
V
Sbjct: 748 FSV 750
Score = 91.1 bits (216), Expect = 3e-16
Identities = 77/311 (24%), Positives = 147/311 (47%), Gaps = 22/311 (7%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFV- 1596
F+ + + + N + + L + + +LD+LN F +F E KI L +V
Sbjct: 1951 FNNLATIAVFANTVVLALAGSFSDDQSNQILDWLNNFFTFVFIGEMAFKIIGLTPAGYVR 2010
Query: 1597 EPWNLFDFVVVMFSILSLVL-SDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLL 1655
+ N+FD +V SIL LV+ S K F + +R+ R +V RV RL++G + + ++
Sbjct: 2011 DRMNIFDGFIVCLSILELVIFSGSGSKAFSAFRSVRIFRTFRVLRVTRLLRGLEFMGVII 2070
Query: 1656 FALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQM 1715
++ +L + I LLFL +FIF + GM + NF F I +FQ+
Sbjct: 2071 KVISRTLDSFIYIAFLLFLFIFIFTLLGMQIYGGKLQIIDPRVRQNFDNFQNGFITVFQL 2130
Query: 1716 STSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAV 1775
T W+ +L N S N +I YL+ ++ I I +N+++A+
Sbjct: 2131 MTIENWNDILYKTFN------------SSVNKFLTSI---YLIVWIFIGNWIFLNLFLAI 2175
Query: 1776 ILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLS-DFLDVLEPPLQIHK 1834
+L+ ++ ++ ++ L +D D Y E + D + ++ +++QL+ + L +L +
Sbjct: 2176 LLDGFTDQSQ--EDSLALEDEDQYEE--EVVDKNENKNQQFNQLNQENLQILNEDFERMD 2231
Query: 1835 PNKYKIISMDI 1845
+ ++I +I
Sbjct: 2232 SEEMELIEQEI 2242
Score = 74.5 bits (175), Expect = 3e-11
Identities = 42/186 (22%), Positives = 101/186 (54%), Gaps = 12/186 (6%)
Query: 107 SKGKDIF-RFSATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTP- 164
S+ + +F +++L++ N IR + I+ HP F I+ I+ + + +++ T
Sbjct: 2249 SQNQQLFIGIECSHSLYLFSKQNSIRILFYKIVKHPQFENLILFFIVTSSLKLVVDTYVD 2308
Query: 165 -------TVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM 217
+++ +++F I+ E+ +K+++ GFI +YL ++W+ +DF ++ + + M
Sbjct: 2309 EHSDVGIALKNVDLMFNFIFIAEATLKIISFGFIGDENSYLDESWSQIDFFIVCTSIIDM 2368
Query: 218 ---GIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFA 274
G+++ + LR R LR L+ ++ +K +V A+ ES+ + +++I+ +FA
Sbjct: 2369 TFSGVNVSFIKILRLLRTLRPLRFISHNVNMKVVVIALFESISGIFNILIVIFLIWIMFA 2428
Query: 275 LMGLQI 280
++G+ +
Sbjct: 2429 ILGISL 2434
Score = 72.1 bits (169), Expect = 1e-10
Identities = 48/163 (29%), Positives = 80/163 (49%), Gaps = 13/163 (7%)
Query: 1530 FEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFA 1589
++I+ F+ I+L I N + + LD ++ S+ D+ F+ ++ E LKI A
Sbjct: 515 YKIIKSNWFENTILLIIIFNSIMLMLDD-PTTDVQSSFADWCEQFFLWAYTVEACLKIIA 573
Query: 1590 LRY-----HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRL 1644
L + Y + WN+ DF +V+ S+L LV+ S LR +R ++ R LR
Sbjct: 574 LGFILPQGAYLKDGWNILDFAIVVSSLLPLVIGS-------STVNLRALRSLRILRPLRT 626
Query: 1645 VKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+ K ++ LL L ++P L N ++L IFAI G+ F
Sbjct: 627 ISKVKKLKILLKTLFSAIPYLVNSMIILTFFFLIFAIGGLQLF 669
Score = 64.1 bits (149), Expect = 4e-08
Identities = 62/282 (21%), Positives = 125/282 (44%), Gaps = 39/282 (13%)
Query: 1215 IENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLAL 1274
+++++F + +++ LAL + IL +++ FT +F EM K + L
Sbjct: 1946 VKSSFFNNLATIAVFANTVVLALAGSFSDDQS--NQILDWLNNFFTFVFIGEMAFKIIGL 2003
Query: 1275 GFQKYFTNAWCWLDFIIVMVSLINFVA-ALCGAGGIQAFKTMRTLRALRPLRAMSRMQG- 1332
Y + D IV +S++ V + G+ AF+++R R R LR ++G
Sbjct: 2004 TPAGYVRDRMNIFDGFIVCLSILELVIFSGSGSKAFSAFRSVRIFRTFRVLRVTRLLRGL 2063
Query: 1333 --MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIP 1390
M V++ + + + S + + +F IF ++G+Q++ GK +II
Sbjct: 2064 EFMGVIIKVISRTLDSFIYIAFLLFLFIFIFTLLGMQIYGGKL-------------QIID 2110
Query: 1391 DKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETN 1450
+ +N FD+ ++ +FQ+ T + W I+ +S V + T+
Sbjct: 2111 PR---VRQN---------FDNFQNGFITVFQLMTIENWNDILYKTFNS-SVNK---FLTS 2154
Query: 1451 IYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLE 1492
IY+ ++ LNLF+ +++D F +Q ++ +LE
Sbjct: 2155 IYLIVWIFIGNWIF----LNLFLAILLDGFTDQSQEDSLALE 2192
Score = 54.4 bits (125), Expect = 3e-05
Identities = 56/230 (24%), Positives = 107/230 (46%), Gaps = 29/230 (12%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM-----PTT--PTVESTEVIFTGIYT 178
P I ++ I+ + F +FI+ I+ N + M M P++ +E+ + FT +
Sbjct: 2577 PTQKIPKLMYNIVTNQKFEIFIMVLIVCNILTMAMAYEGSPSSYDSILENINLFFTSCFI 2636
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDL-GNLAA----------- 226
E+ +K +A G ++ F + D WN D V+ + V + ++ G L+A
Sbjct: 2637 LETIMKFIAFG--IKGF-FAND-WNKFDLFVVVSSIVDIILNYSGALSASFLRIGPQLIR 2692
Query: 227 -LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVL 285
+R FRV R LK V + GL+ ++ ++ S+ +L +V L + +++++G+ ++ V
Sbjct: 2693 IIRVFRVSRLLKLVKSMKGLQKLIETLMFSLPSLINVGALLLLVFFIYSILGVFMFKDVT 2752
Query: 286 TQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQ 335
+ + ++GN + C NWY D CG +SG Q
Sbjct: 2753 EGVVIDKYNNFENFGNAMITLFR--CSTGENWYQFMFD---CGKTSGCVQ 2797
Score = 48.4 bits (110), Expect = 0.002
Identities = 27/94 (28%), Positives = 54/94 (57%), Gaps = 7/94 (7%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LRV +L + + ++I ++ RT+ + + F+L + IFIF ++GMQ++G + +D
Sbjct: 2054 LRVTRLLRGLEFMGVIIKVISRTLDSFIYIAFLLFLFIFIFTLLGMQIYG-GKLQIID-- 2110
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMW 925
R NF +F + F+ VF+++ E W + ++
Sbjct: 2111 ---PRVRQNFDNFQNGFITVFQLMTIENWNDILY 2141
Score = 47.2 bits (107), Expect = 0.005
Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 16/124 (12%)
Query: 173 FTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN-------LA 225
FT ++ E A K++ L P Y+RD N D ++ L+ + + I G+
Sbjct: 1988 FTFVFIGEMAFKIIG----LTPAGYVRDRMNIFDGFIVCLSILELVIFSGSGSKAFSAFR 2043
Query: 226 ALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLS----VFALMGLQIY 281
++R FR R L+ ++ GL+ +G +I+ + D I F L +F L+G+QIY
Sbjct: 2044 SVRIFRTFRVLRVTRLLRGLE-FMGVIIKVISRTLDSFIYIAFLLFLFIFIFTLLGMQIY 2102
Query: 282 MGVL 285
G L
Sbjct: 2103 GGKL 2106
Score = 44.0 bits (99), Expect = 0.042
Identities = 34/139 (24%), Positives = 73/139 (52%), Gaps = 12/139 (8%)
Query: 793 FDPFVELFITLCIVVN-TLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISI 851
FD FV + + I++N + ++ + + + ++ R+ KL KS L LI
Sbjct: 2659 FDLFVVVSSIVDIILNYSGALSASFLRIGPQLIRIIRVFRVSRLLKLVKSMKGLQKLIET 2718
Query: 852 MGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVD--YVDRFPDGDLPRWNFTDFMHSF 909
+ ++ +L N+ +L ++ FI++++G+ +F K+ + +D++ NF +F ++
Sbjct: 2719 LMFSLPSLINVGALLLLVFFIYSILGVFMF-KDVTEGVVIDKYN-------NFENFGNAM 2770
Query: 910 MIVFRVLCGE-WIESMWDC 927
+ +FR GE W + M+DC
Sbjct: 2771 ITLFRCSTGENWYQFMFDC 2789
>UniRef50_UPI0000F2E940 Cluster: PREDICTED: similar to voltage-gated
L-type calcium channel alpha-1 subunit; n=1; Monodelphis
domestica|Rep: PREDICTED: similar to voltage-gated L-type
calcium channel alpha-1 subunit - Monodelphis domestica
Length = 2055
Score = 262 bits (641), Expect = 9e-68
Identities = 204/739 (27%), Positives = 353/739 (47%), Gaps = 106/739 (14%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
LR+ LI + F ++ I+LSS++LA ED H +L Y D FT IF IE
Sbjct: 817 LRVHCHALIHHRIFTNLILVFIILSSVSLAAEDPIRAHS-FRNHVLGYFDYAFTSIFTIE 875
Query: 1267 MLIKWLALGFQKYFT------NAWCW-----------------------LDFIIVMVSLI 1297
+L+K + L + W W LD ++V VSLI
Sbjct: 876 ILLKVILLPLPSTIRGPAAPPSPWVWGSQMTAFGAFLHRGSFCRNWFNLLDLLVVSVSLI 935
Query: 1298 NFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIF 1357
+F + I K +R LR LRPLRA++R +G++ VV + AI +I N+L+V +
Sbjct: 936 SFGIH---SSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNILIVTSLL 992
Query: 1358 WLIFAIMGVQLFAGKYFKCVD-MNHTTLSHE----IIPDKNAC--TLENYTWENSPMNFD 1410
+FA +GVQLF GK + C D HT + + PD + + W+NS NFD
Sbjct: 993 QFMFACIGVQLFKGKLYSCTDEAKHTPTECKGTFLVYPDGDVAHPVMRERVWQNSDFNFD 1052
Query: 1411 HVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLN 1470
+V A + LF V+TF+GW ++ AID+ + PI + + ++ +N
Sbjct: 1053 NVLSAMMALFTVSTFEGWPSLLYKAIDAHAEDQGPIYNYRLEISVFFIVYIIIIAFFMMN 1112
Query: 1471 LFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGS------------------- 1511
+F+G +I F Q ++ + E+ + N GS
Sbjct: 1113 IFVGFVIITFRAQGEQEYKNCELDKNQVATLTSNLHGVFGSWSATAHLHCSPPPSPLQRQ 1172
Query: 1512 --KKPLKAIPR----PRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFS 1565
+ LKA P PR R Q V+ V F+ ++ L I LN +T+ + HY+Q+ F+
Sbjct: 1173 CVEYALKAQPLRRYIPRNRHQHRVWATVNSPAFEYLMFLLILLNTITLAMQHYEQTAPFN 1232
Query: 1566 AVLDYLNMIFIVIFSSECLLKIFALR-YHYFVEPWNLFDFVVVMFSILSLVLSDI----- 1619
+D LNM+F +F+ E LLK+ A + HYF + WN FD ++V+ S++ + ++++
Sbjct: 1233 YTMDVLNMVFTGLFTVEMLLKVIAFKPKHYFCDAWNTFDALIVVGSVVDIAVTEVNFLPS 1292
Query: 1620 -IEKYFVSPTLLRVVRVAKVGRVLRLV-------------------KGAKGIRTLLFAL- 1658
+ + + P L+ +V ++ ++ + + I F L
Sbjct: 1293 FLPLFHLLPCLILLVVCLVTSTIVSIISSIFSAIAITPRMEDTLSSEDSSRISITFFRLF 1352
Query: 1659 -AMSLPALFNICLLLFLVMFIFAIFGMSFF--MHVKDKGGLDDVYNFKTFVQSMILLFQM 1715
M L AL + LL+ ++ FI+A+ GM F + ++D ++ NF+TF Q+++LLF+
Sbjct: 1353 RVMRL-ALPYVALLIAMIFFIYAVIGMQMFGKVALQDGTQINRNNNFQTFPQAVLLLFRC 1411
Query: 1716 STSAGWDGVLDGIINEEECDLPDNE--RGSPGNCGSATIGITYLLSYLVISFLIVINMYI 1773
+T W ++ + + CD P+++ G CGS T I Y +S+ ++ ++IN+++
Sbjct: 1412 ATGEAWQEIMLASLPGKRCD-PESDFTAGEEFTCGS-TFAIVYFISFFMLCAFLIINLFV 1469
Query: 1774 AVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIH 1833
AVI++N+ T D L D + +W +DP +I++ + L ++PPL
Sbjct: 1470 AVIMDNFDYLTRD-WSILGPHHLDEFKRVWSEYDPGAKGHIKHLDVVALLRRIQPPLGFG 1528
Query: 1834 K--PNKY---KIISMDIPI 1847
K P++ ++++M++P+
Sbjct: 1529 KLCPHRVACKRLVAMNMPL 1547
Score = 84.2 bits (199), Expect = 3e-14
Identities = 66/257 (25%), Positives = 124/257 (48%), Gaps = 22/257 (8%)
Query: 1541 IIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL-RYHYFVEPW 1599
+++L + LN LT+ +H+ Q + + N + +++F+ E LLK++ L Y +
Sbjct: 468 LVLLLVFLNTLTIASEHHGQPLWLTQTQESANKVLLLLFTVEMLLKLYGLGPTAYAASFF 527
Query: 1600 NLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRL-VKGAKGIRTLLFAL 1658
N FD VV IL L + + ++LR VR+ ++ +V R K + L+ +L
Sbjct: 528 NRFDCFVVCGGILETTLVEAGAMQSLGISVLRCVRLLRIFKVTRSETKHWASLSNLVASL 587
Query: 1659 AMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVY----NFKTFVQSMILLFQ 1714
S+ ++ ++ LLLFL + IF++ GM F K D + F TF Q+++ +FQ
Sbjct: 588 LNSMKSIASLLLLLFLFLIIFSLLGMQLF---GGKFNFDQTHTKRSTFDTFPQALLTVFQ 644
Query: 1715 MSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYI 1773
+ T W+ V+ DGI+ G P G + Y + + I++N+++
Sbjct: 645 ILTGEDWNVVMYDGIL----------AYGGPFFPG--MLVCIYFIILFICGNYILLNVFL 692
Query: 1774 AVILENYSQATEDVQEG 1790
A+ ++N + +G
Sbjct: 693 AIAVDNLAGGDASASKG 709
Score = 70.1 bits (164), Expect = 6e-10
Identities = 47/148 (31%), Positives = 75/148 (50%), Gaps = 27/148 (18%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILM-IMPTTP---------TVEST 169
AL+ L NP+RR I I+ F + I+ TI NC+ + + P +E
Sbjct: 87 ALFCLSLTNPVRRFCITIVEWKPFDILILMTIFANCVALGVYVPFPEDDSNAGNHNLEQV 146
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLG------- 222
E F I+T E+A+K++A G +L P Y+R+ WN LDFV++ + ++ ++ G
Sbjct: 147 EYAFLVIFTVETALKIVAYGLVLHPNAYIRNGWNLLDFVIVVVGLFSVLLEQGPPRPGDA 206
Query: 223 ----------NLAALRTFRVLRALKTVA 240
++ ALR FRVLR L+ V+
Sbjct: 207 SHAAGKPGGFDVKALRAFRVLRPLRLVS 234
Score = 64.1 bits (149), Expect = 4e-08
Identities = 65/278 (23%), Positives = 122/278 (43%), Gaps = 34/278 (12%)
Query: 1206 TLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFI 1265
TLR + +++ V+ ++ L++L +A E H L +++ ++F +
Sbjct: 451 TLRARCRHAVKSVACYWLVLLLVFLNTLTIASE--HHGQPLWLTQTQESANKVLLLLFTV 508
Query: 1266 EMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAG---GIQAFKTMRTLRALR 1322
EML+K LG Y + + D +V ++ GA GI + +R LR +
Sbjct: 509 EMLLKLYGLGPTAYAASFFNRFDCFVVCGGILETTLVEAGAMQSLGISVLRCVRLLRIFK 568
Query: 1323 PLRAMSR-MQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNH 1381
R+ ++ + +V +L+ ++ SI ++LL+ +F +IF+++G+QLF GK+ D H
Sbjct: 569 VTRSETKHWASLSNLVASLLNSMKSIASLLLLLFLFLIIFSLLGMQLFGGKF--NFDQTH 626
Query: 1382 TTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREV 1441
T S FD +A L +FQ+ T + W +M D I +
Sbjct: 627 TKRS----------------------TFDTFPQALLTVFQILTGEDWNVVMYDGILAYGG 664
Query: 1442 GRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDN 1479
P + + +Y LN+F+ + +DN
Sbjct: 665 PFFP----GMLVCIYFIILFICGNYILLNVFLAIAVDN 698
Score = 57.2 bits (132), Expect = 4e-06
Identities = 30/105 (28%), Positives = 61/105 (58%), Gaps = 3/105 (2%)
Query: 184 KVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA---LRTFRVLRALKTVA 240
++ A G L ++ R+ +N LD +V++++ ++ GI ++ LR RVLR L+ +
Sbjct: 904 QMTAFGAFLHRGSFCRNWFNLLDLLVVSVSLISFGIHSSAISVVKILRVLRVLRPLRAIN 963
Query: 241 IVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVL 285
GLK +V V +++ + +++I+T +FA +G+Q++ G L
Sbjct: 964 RAKGLKHVVQCVFVAIRTIGNILIVTSLLQFMFACIGVQLFKGKL 1008
Score = 54.4 bits (125), Expect = 3e-05
Identities = 33/108 (30%), Positives = 59/108 (54%), Gaps = 10/108 (9%)
Query: 827 LKSGNYLRVFKLAKS----WPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFG 882
L+ LR+FK+ +S W +L+ L++ + +M ++ +L +L + + IF+++GMQLFG
Sbjct: 558 LRCVRLLRIFKVTRSETKHWASLSNLVASLLNSMKSIASLLLLLFLFLIIFSLLGMQLFG 617
Query: 883 KNYVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCML 929
+ F R F F + + VF++L GE W M+D +L
Sbjct: 618 GKF-----NFDQTHTKRSTFDTFPQALLTVFQILTGEDWNVVMYDGIL 660
Score = 45.2 bits (102), Expect = 0.018
Identities = 36/125 (28%), Positives = 61/125 (48%), Gaps = 14/125 (11%)
Query: 141 PLFSLFIITTILVNCILMIMP----TTP---TVESTEVIFTGIYTFESAVKVMARGFILQ 193
P F + IL+N I + M T P T++ ++FTG++T E +KV+A +
Sbjct: 1203 PAFEYLMFLLILLNTITLAMQHYEQTAPFNYTMDVLNMVFTGLFTVEMLLKVIA----FK 1258
Query: 194 PFTYLRDAWNWLDFVVIALAYVTMGIDLGNL--AALRTFRVLRALKTVAIVPGLKTIVGA 251
P Y DAWN D +++ + V + + N + L F +L L + + TIV +
Sbjct: 1259 PKHYFCDAWNTFDALIVVGSVVDIAVTEVNFLPSFLPLFHLLPCLILLVVCLVTSTIV-S 1317
Query: 252 VIESV 256
+I S+
Sbjct: 1318 IISSI 1322
Score = 44.8 bits (101), Expect = 0.024
Identities = 24/81 (29%), Positives = 45/81 (55%), Gaps = 12/81 (14%)
Query: 336 CEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENL---------YQ---LF 383
C + +G PN G T+FD F +A L+ F+ +T + W ++ Y+ L+
Sbjct: 236 CLGNHTECRGRWAGPNGGITNFDNFFFAMLTVFQCVTMEGWTDVLYWVQDAMGYELPWLY 295
Query: 384 FVVIIFLGSFYLVNLILAIVA 404
FV ++ GSF+++NL+L +++
Sbjct: 296 FVSLVIFGSFFVLNLVLGVLS 316
Score = 44.0 bits (99), Expect = 0.042
Identities = 44/165 (26%), Positives = 76/165 (46%), Gaps = 17/165 (10%)
Query: 130 IRRVAIYILVHPLFSLFIIT-TILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMAR 188
++ VA Y LV L +F+ T TI + T T ES + ++T E +K+
Sbjct: 460 VKSVACYWLV--LLLVFLNTLTIASEHHGQPLWLTQTQESANKVLLLLFTVEMLLKLYGL 517
Query: 189 GFILQPFTYLRDAWNWLD-FVVIALAYVTMGIDLG-----NLAALRTFRVLRALKTVAIV 242
G P Y +N D FVV T ++ G ++ LR R+LR K
Sbjct: 518 G----PTAYAASFFNRFDCFVVCGGILETTLVEAGAMQSLGISVLRCVRLLRIFKVTRSE 573
Query: 243 P----GLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
L +V +++ S+K++ +++L L +F+L+G+Q++ G
Sbjct: 574 TKHWASLSNLVASLLNSMKSIASLLLLLFLFLIIFSLLGMQLFGG 618
Score = 41.1 bits (92), Expect = 0.30
Identities = 31/93 (33%), Positives = 48/93 (51%), Gaps = 8/93 (8%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLD---HYQQSETFSAVLDYLNMIFIVIFSSECLLKIF 1588
IV K FD++I++ I N + + + S + L+ + F+VIF+ E LKI
Sbjct: 104 IVEWKPFDILILMTIFANCVALGVYVPFPEDDSNAGNHNLEQVEYAFLVIFTVETALKIV 163
Query: 1589 A--LRYH---YFVEPWNLFDFVVVMFSILSLVL 1616
A L H Y WNL DFV+V+ + S++L
Sbjct: 164 AYGLVLHPNAYIRNGWNLLDFVIVVVGLFSVLL 196
Score = 39.9 bits (89), Expect = 0.69
Identities = 33/96 (34%), Positives = 44/96 (45%), Gaps = 15/96 (15%)
Query: 1252 LYYMDRIFTVIFFIEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVA------ 1301
L ++ F VIF +E +K +A G Y N W LDF+IV+V L + +
Sbjct: 143 LEQVEYAFLVIFTVETALKIVAYGLVLHPNAYIRNGWNLLDFVIVVVGLFSVLLEQGPPR 202
Query: 1302 ---ALCGAGGIQAF--KTMRTLRALRPLRAMSRMQG 1332
A AG F K +R R LRPLR +S G
Sbjct: 203 PGDASHAAGKPGGFDVKALRAFRVLRPLRLVSGCLG 238
Score = 37.5 bits (83), Expect = 3.7
Identities = 23/68 (33%), Positives = 37/68 (54%), Gaps = 5/68 (7%)
Query: 858 ALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLC 917
AL + ++ +I FI+AV+GMQ+FGK + + + NF F + +++FR
Sbjct: 1358 ALPYVALLIAMIFFIYAVIGMQMFGKVALQDGTQINRNN----NFQTFPQAVLLLFRCAT 1413
Query: 918 GE-WIESM 924
GE W E M
Sbjct: 1414 GEAWQEIM 1421
>UniRef50_UPI000051A6E6 Cluster: PREDICTED: similar to Ca-1T
CG15899-PB, partial; n=1; Apis mellifera|Rep: PREDICTED:
similar to Ca-1T CG15899-PB, partial - Apis mellifera
Length = 942
Score = 258 bits (632), Expect = 1e-66
Identities = 143/490 (29%), Positives = 268/490 (54%), Gaps = 31/490 (6%)
Query: 1316 RTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK 1375
R LR+LRPLR ++R G+++VV L+ ++ I N++L+C F++IF I+GVQLF G ++
Sbjct: 3 RLLRSLRPLRVINRAPGLKLVVQTLLSSLRPIGNIVLICCTFFVIFGILGVQLFKGAFYY 62
Query: 1376 C--VDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMN 1433
C D+ + + + DK W N NFD +GKA + LF +++ GW+ IM
Sbjct: 63 CEGPDIKNVRNKTDCLADK------RNVWLNRKYNFDDLGKALMSLFVLSSRDGWVNIMY 116
Query: 1434 DAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEM 1493
+D+ V +QPI + + LY LN+F+GV+++NF+ +++
Sbjct: 117 TGLDAVGVDQQPIENYSEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCREE------- 169
Query: 1494 FMTEDQKKYYNAMKKMGSKKPLKAIPRPRW-----RPQAIVFEIVTDKKFDMIIMLFIGL 1548
++++ A + + +K + + P + + + V +VT K FD+ I IGL
Sbjct: 170 -QEKEERVRRAAKRALQMEKKRRKMHEPPYYTNYSKSRLFVHNVVTSKYFDLAIAAVIGL 228
Query: 1549 NMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVV 1607
N++TM ++ Y + + L N F +F E +K+ AL H Y + WN D +V
Sbjct: 229 NVVTMAMEFYMMPKALTYALKIFNYFFTAVFILESFMKLLALGLHLYLKDKWNQLDVGIV 288
Query: 1608 MFSILSLVLSDIIEKYF-VSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALF 1666
+ S++ +VL ++ K ++PT++RV+RV ++ RVL+L+K AKGIR LL + +LP +
Sbjct: 289 ILSVVGIVLEEVESKIIPINPTIIRVMRVLRIARVLKLLKMAKGIRALLDTVMQALPQVG 348
Query: 1667 NICLLLFLVMFIFAIFGMSFF--MHVKDK---GGLDDVYNFKTFVQSMILLFQMSTSAGW 1721
N+ LL FL+ FIFA G+ F + D GL + +F F + + LF+++T W
Sbjct: 349 NLGLLFFLLFFIFAALGVELFGRLECSDDMPCQGLGEHAHFSNFGMAFLTLFRVATGDNW 408
Query: 1722 DGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYS 1781
+G++ + ++ + D + C S I + + +++++ +++N+ +AV++++
Sbjct: 409 NGIMKDTLRDDCDEAADCVKNC---CVSTIIAPIFFVIFVLMAQFVLVNVVVAVLMKHLE 465
Query: 1782 QATEDVQEGL 1791
++ + +++ L
Sbjct: 466 ESHKQMEDEL 475
Score = 96.3 bits (229), Expect = 8e-18
Identities = 77/305 (25%), Positives = 142/305 (46%), Gaps = 30/305 (9%)
Query: 1197 DSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMD 1256
+ P++ + RL ++ + YF+ A+ +I L+ + +A+E +P L L +
Sbjct: 195 EPPYYTNYSKSRLFVHNVVTSKYFDLAIAAVIGLNVVTMAMEFYMMPKA--LTYALKIFN 252
Query: 1257 RIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQA----F 1312
FT +F +E +K LALG Y + W LD IV++S++ V + I
Sbjct: 253 YFFTAVFILESFMKLLALGLHLYLKDKWNQLDVGIVILSVVGIVLEEVESKIIPINPTII 312
Query: 1313 KTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGK 1372
+ MR LR R L+ + +G+R +++ ++QA+P + N+ L+ + + IFA +GV+LF G+
Sbjct: 313 RVMRVLRIARVLKLLKMAKGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELF-GR 371
Query: 1373 YFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIM 1432
+C D D L + +F + G A+L LF+VAT W IM
Sbjct: 372 -LECSD------------DMPCQGLGEHA------HFSNFGMAFLTLFRVATGDNWNGIM 412
Query: 1433 NDAI-DSREVGRQPIRE---TNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAG 1488
D + D + ++ + I ++ +N+ + V++ + E K+
Sbjct: 413 KDTLRDDCDEAADCVKNCCVSTIIAPIFFVIFVLMAQFVLVNVVVAVLMKHLEESHKQME 472
Query: 1489 GSLEM 1493
L+M
Sbjct: 473 DELDM 477
Score = 52.8 bits (121), Expect = 9e-05
Identities = 32/144 (22%), Positives = 72/144 (50%), Gaps = 14/144 (9%)
Query: 148 ITTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDF 207
+ T+ + +M T ++ FT ++ ES +K++A G L YL+D WN LD
Sbjct: 230 VVTMAMEFYMMPKALTYALKIFNYFFTAVFILESFMKLLALGLHL----YLKDKWNQLDV 285
Query: 208 VVIALAYV----------TMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVK 257
++ L+ V + I+ + +R R+ R LK + + G++ ++ V++++
Sbjct: 286 GIVILSVVGIVLEEVESKIIPINPTIIRVMRVLRIARVLKLLKMAKGIRALLDTVMQALP 345
Query: 258 NLRDVIILTMFSLSVFALMGLQIY 281
+ ++ +L +FA +G++++
Sbjct: 346 QVGNLGLLFFLLFFIFAALGVELF 369
Score = 47.6 bits (108), Expect = 0.003
Identities = 30/97 (30%), Positives = 53/97 (54%), Gaps = 4/97 (4%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
RV KL K + L+ + + + +GNL + ++ FIFA +G++LFG+ ++ D P
Sbjct: 322 RVLKLLKMAKGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELFGR--LECSDDMP 379
Query: 894 -DGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
G +F++F +F+ +FRV G+ W M D +
Sbjct: 380 CQGLGEHAHFSNFGMAFLTLFRVATGDNWNGIMKDTL 416
Score = 40.7 bits (91), Expect = 0.40
Identities = 15/56 (26%), Positives = 34/56 (60%)
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
R R LR L+ + PGLK +V ++ S++ + +++++ +F ++G+Q++ G
Sbjct: 3 RLLRSLRPLRVINRAPGLKLVVQTLLSSLRPIGNIVLICCTFFVIFGILGVQLFKG 58
Score = 36.3 bits (80), Expect = 8.5
Identities = 14/49 (28%), Positives = 27/49 (55%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
LR ++ P L L++ + ++ +GN+ + C IF ++G+QLF
Sbjct: 8 LRPLRVINRAPGLKLVVQTLLSSLRPIGNIVLICCTFFVIFGILGVQLF 56
>UniRef50_UPI000065DC23 Cluster: Voltage-dependent T-type calcium
channel subunit alpha-1H (Voltage- gated calcium channel
subunit alpha Cav3.2) (Low-voltage-activated calcium
channel alpha1 3.2 subunit).; n=1; Takifugu rubripes|Rep:
Voltage-dependent T-type calcium channel subunit alpha-1H
(Voltage- gated calcium channel subunit alpha Cav3.2)
(Low-voltage-activated calcium channel alpha1 3.2
subunit). - Takifugu rubripes
Length = 1639
Score = 257 bits (629), Expect = 3e-66
Identities = 169/577 (29%), Positives = 297/577 (51%), Gaps = 63/577 (10%)
Query: 1258 IFTVIFFIEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAF- 1312
IFTVIF EM+IK +A+G Y ++W LD ++V VSL++ + ++ AGG + F
Sbjct: 1070 IFTVIFVGEMMIKVVAMGLYFGHSVYLQSSWNILDGLLVFVSLVDILVSVASAGGNRIFG 1129
Query: 1313 --KTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
+ +R LR LRPLR +SR G+++VV L+ ++ I N++L+C F+++F I+GVQLF
Sbjct: 1130 ILRVLRLLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVLICCAFFIVFGILGVQLFK 1189
Query: 1371 GKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQ 1430
GK++ C ++ + I +K C Y W NFD++G+A + LF ++ GW+
Sbjct: 1190 GKFYYCDGLDVSN-----IINKTQCLGAGYRWIRRKYNFDNLGQALMSLFVLSCKDGWVS 1244
Query: 1431 IMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGS 1490
IM D +D+ V +QP R + +M L+ LN+F+GV+++NF++ +++
Sbjct: 1245 IMYDGLDAVGVDQQPKRNHDPWMLLFFISFLLIVSFFVLNMFVGVVVENFHKCRQQQEEE 1304
Query: 1491 LEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNM 1550
E ++K ++ +KP A P WR + + T D+ I + I N+
Sbjct: 1305 EARLREEKRQKRLEKRRRKAQEKPYYADYAP-WRRS--IHTVCTSNYLDLFITIIIFTNL 1361
Query: 1551 LTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKI--FALRYHYFVEPWNLFDFVVVM 1608
LTM+++HY Q + F +L Y N +F V+F E +LK+ F LR +F E WN D +V+
Sbjct: 1362 LTMSMEHYNQPKYFEEILKYCNYVFTVVFVIEAILKLVAFGLR-RFFKERWNQLDLAIVL 1420
Query: 1609 FSILSLVLS--DIIEKYFVSPTLLRVVRVAKVGRVLRLVKGA---KGIRT---------- 1653
SI+ + L D+ ++PT++R++RV ++ R + A K T
Sbjct: 1421 LSIMGITLEEIDLNASLPINPTIIRIMRVLRITRGMHTYTRAVRHKYTETRAVWLMSPCN 1480
Query: 1654 ----LLFALAMSLPALFNICL----------LLF-LVMFIFAIFGMSFF--MHVKDKG-- 1694
L +A + AL + + LLF L+ FI+A G+ F + D
Sbjct: 1481 VSVLKLLKMATGMRALLDTVIQALPQVGNLGLLFMLLFFIYAALGVELFGKLECSDNNPC 1540
Query: 1695 -GLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGS--AT 1751
GL F F + + LF++ST W+G++ + EC R +C +
Sbjct: 1541 EGLSRHATFDNFGMAFLTLFRVSTGDNWNGIMKDTL--REC------RPLDRHCLTYLPF 1592
Query: 1752 IGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQ 1788
I Y +++++ + +++N+ +AV++++ + ++ Q
Sbjct: 1593 ISPVYFVTFVLTAQFVLVNVVVAVLMKHLEDSNKEAQ 1629
Score = 100 bits (239), Expect = 5e-19
Identities = 65/224 (29%), Positives = 119/224 (53%), Gaps = 15/224 (6%)
Query: 1509 MGSKKPLKAIPRPRWRPQAIVFEIVTDKK-FDMIIMLFIGLNMLTMTLDHYQQSETFSAV 1567
M S +P + + + W +++ + F+ IM+ I +N L+M +++++Q + + +
Sbjct: 457 MQSPEPKRKLYKRCWAGLRTKLDLIVGSRYFNRGIMIAILINTLSMGIEYHEQPQELTDI 516
Query: 1568 LDYLNMIFIVIFSSECLLKIFAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVS 1626
L+ NM+F +FS E LLK+ AL + Y P+N FD ++V+ S+ +V +
Sbjct: 517 LEITNMVFTSLFSLEMLLKLLALGLFGYIKNPYNGFDSIIVIISVWEIVGE--------A 568
Query: 1627 PTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSF 1686
L V+R ++ RVL+LV+ +R L L ++ + C+LL L +FIF+I GM
Sbjct: 569 EGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLIKTMDNVATFCMLLMLFIFIFSILGMHL 628
Query: 1687 F---MHVKDKGG--LDDVYNFKTFVQSMILLFQMSTSAGWDGVL 1725
F ++ + G L D NF + + + + +FQ+ T W+ VL
Sbjct: 629 FGCKFGLRQESGDTLPDRKNFDSLLWATVTVFQILTQEDWNSVL 672
Score = 92.3 bits (219), Expect = 1e-16
Identities = 76/303 (25%), Positives = 138/303 (45%), Gaps = 40/303 (13%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W LR K ++ + YF ++ IL+++L++ +E P L DIL + +FT +F
Sbjct: 471 WAGLRTKLDLIVGSRYFNRGIMIAILINTLSMGIEYHEQPQE--LTDILEITNMVFTSLF 528
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRP 1323
+EML+K LALG Y N + D IIV++S+ V GG+ +T R LR L+
Sbjct: 529 SLEMLLKLLALGLFGYIKNPYNGFDSIIVIISVWEIVGE--AEGGLSVLRTFRLLRVLKL 586
Query: 1324 LRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTT 1383
+R + ++ VV L++ + ++ ++ ++F IF+I+G+ LF K+
Sbjct: 587 VRFLPALRRQLVV---LIKTMDNVATFCMLLMLFIFIFSILGMHLFGCKF------GLRQ 637
Query: 1384 LSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGR 1443
S + +PD+ NFD + A + +FQ+ T + W ++ + + S
Sbjct: 638 ESGDTLPDRK--------------NFDSLLWATVTVFQILTQEDWNSVLYNGMAS----- 678
Query: 1444 QPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGS---LEMFMTEDQK 1500
T LY NL + ++++ F + + S +E+ +D K
Sbjct: 679 -----TTPLAALYFVALMTFGNYVLFNLLVAILVEGFQAEVRANMQSMRLIELCCADDTK 733
Query: 1501 KYY 1503
Y
Sbjct: 734 AAY 736
Score = 72.1 bits (169), Expect = 1e-10
Identities = 66/307 (21%), Positives = 131/307 (42%), Gaps = 20/307 (6%)
Query: 1197 DSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMD 1256
+ P++ + R + + Y + + +I + L +++E + P ++IL Y +
Sbjct: 1326 EKPYYADYAPWRRSIHTVCTSNYLDLFITIIIFTNLLTMSMEHYNQPK--YFEEILKYCN 1383
Query: 1257 RIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGI-----QA 1311
+FTV+F IE ++K +A G +++F W LD IV++S++
Sbjct: 1384 YVFTVVFVIEAILKLVAFGLRRFFKERWNQLDLAIVLLSIMGITLEEIDLNASLPINPTI 1443
Query: 1312 FKTMRTLRALRPLRAMSR-MQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
+ MR LR R + +R ++ A+ P +VL + + + A++ + A
Sbjct: 1444 IRIMRVLRITRGMHTYTRAVRHKYTETRAVWLMSPCNVSVLKLLKMATGMRALLDTVIQA 1503
Query: 1371 -------GKYFKCVDMNHTTLSHEIIPDKNACTLENYTWE--NSPMNFDHVGKAYLCLFQ 1421
G F + + L E+ K C+ +N E + FD+ G A+L LF+
Sbjct: 1504 LPQVGNLGLLFMLLFFIYAALGVELF-GKLECS-DNNPCEGLSRHATFDNFGMAFLTLFR 1561
Query: 1422 VATFKGWIQIMNDAI-DSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNF 1480
V+T W IM D + + R + R + +Y +N+ + V++ +
Sbjct: 1562 VSTGDNWNGIMKDTLRECRPLDRHCLTYLPFISPVYFVTFVLTAQFVLVNVVVAVLMKHL 1621
Query: 1481 NEQKKKA 1487
+ K+A
Sbjct: 1622 EDSNKEA 1628
Score = 71.7 bits (168), Expect = 2e-10
Identities = 34/120 (28%), Positives = 73/120 (60%), Gaps = 5/120 (4%)
Query: 163 TPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALA-YVTMGIDL 221
T +E T ++FT +++ E +K++A G F Y+++ +N D +++ ++ + +G
Sbjct: 514 TDILEITNMVFTSLFSLEMLLKLLALGL----FGYIKNPYNGFDSIIVIISVWEIVGEAE 569
Query: 222 GNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
G L+ LRTFR+LR LK V +P L+ + +I+++ N+ +L M + +F+++G+ ++
Sbjct: 570 GGLSVLRTFRLLRVLKLVRFLPALRRQLVVLIKTMDNVATFCMLLMLFIFIFSILGMHLF 629
Score = 67.3 bits (157), Expect = 4e-09
Identities = 74/311 (23%), Positives = 134/311 (43%), Gaps = 60/311 (19%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLD------------HYQ-----QSETFSA-------- 1566
++ K FD +I+LFI LN +T+ L+ H Q Q F+A
Sbjct: 1000 VIGHKMFDHVILLFIFLNCITIALERPDIQPNSTVTSHLQSYVQTQCHRFTAKLYVFTYE 1059
Query: 1567 ---VLDYLNMIFIVIFSSECLLKIFALRYH-----YFVEPWNLFDFVVVMFSILSLVLSD 1618
L N IF VIF E ++K+ A+ + Y WN+ D ++V S++ +++S
Sbjct: 1060 ERVFLSVSNYIFTVIFVGEMMIKVVAMGLYFGHSVYLQSSWNILDGLLVFVSLVDILVSV 1119
Query: 1619 IIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNI---CLLLFLV 1675
+LRV+R+ + R LR++ A G++ ++ L SL + NI C F+V
Sbjct: 1120 ASAGGNRIFGILRVLRLLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVLICCAFFIV 1179
Query: 1676 MFIFAI---FGMSFFMHVKDKGGLDD--------------VYNFKTFVQSMILLFQMSTS 1718
I + G ++ D + + YNF Q+++ LF +S
Sbjct: 1180 FGILGVQLFKGKFYYCDGLDVSNIINKTQCLGAGYRWIRRKYNFDNLGQALMSLFVLSCK 1239
Query: 1719 AGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILE 1778
GW ++ ++ D P + + +S+L+I V+NM++ V++E
Sbjct: 1240 DGWVSIMYDGLDAVGVDQQPKRNHDPWM-------LLFFISFLLIVSFFVLNMFVGVVVE 1292
Query: 1779 NYSQATEDVQE 1789
N+ + + +E
Sbjct: 1293 NFHKCRQQQEE 1303
Score = 67.3 bits (157), Expect = 4e-09
Identities = 36/121 (29%), Positives = 67/121 (55%), Gaps = 9/121 (7%)
Query: 172 IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDL---------G 222
IFT I+ E +KV+A G YL+ +WN LD +++ ++ V + + + G
Sbjct: 1070 IFTVIFVGEMMIKVVAMGLYFGHSVYLQSSWNILDGLLVFVSLVDILVSVASAGGNRIFG 1129
Query: 223 NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYM 282
L LR R LR L+ ++ PGLK +V +I S++ + +++++ VF ++G+Q++
Sbjct: 1130 ILRVLRLLRTLRPLRVISRAPGLKLVVETLITSLRPIGNIVLICCAFFIVFGILGVQLFK 1189
Query: 283 G 283
G
Sbjct: 1190 G 1190
Score = 57.6 bits (133), Expect = 3e-06
Identities = 40/108 (37%), Positives = 56/108 (51%), Gaps = 8/108 (7%)
Query: 143 FSLFIITTILVNCIL--MIMPTTPTVESTEVIFTGIYTF---ESAVKVMARGFILQPFTY 197
F I IL+NC+ M P T + + GI+ F E VK++A G I Q Y
Sbjct: 5 FERVSILAILLNCVTLGMFQPCGHTPFLLQALDDGIFVFFAGEMVVKMVALGVIGQS-GY 63
Query: 198 LRDAWNWLDFVVIALAYVTMGIDLGN--LAALRTFRVLRALKTVAIVP 243
L D WN LDF ++ + + +D N L+A+RT RVLR L+ + VP
Sbjct: 64 LGDTWNRLDFFIVIVGMLEYSLDGHNVSLSAIRTVRVLRPLRAINRVP 111
Score = 53.2 bits (122), Expect = 7e-05
Identities = 43/116 (37%), Positives = 62/116 (53%), Gaps = 11/116 (9%)
Query: 1218 TYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGF- 1276
T+FE I ILL+ + L + H P L L D IF V F EM++K +ALG
Sbjct: 3 TWFERVSILAILLNCVTLGMFQP-CGHTPFLLQALD--DGIF-VFFAGEMVVKMVALGVI 58
Query: 1277 --QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRM 1330
Y + W LDF IV+V ++ + +L G + +RT+R LRPLRA++R+
Sbjct: 59 GQSGYLGDTWNRLDFFIVIVGMLEY--SLDGHN--VSLSAIRTVRVLRPLRAINRV 110
Score = 50.0 bits (114), Expect = 6e-04
Identities = 32/106 (30%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY- 885
L++ LRV KL + P L + ++ +TM + +L + IFIF+++GM LFG +
Sbjct: 575 LRTFRLLRVLKLVRFLPALRRQLVVLIKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFG 634
Query: 886 --VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
+ D PD R NF + + + VF++L E W +++ M
Sbjct: 635 LRQESGDTLPD----RKNFDSLLWATVTVFQILTQEDWNSVLYNGM 676
Score = 46.4 bits (105), Expect = 0.008
Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 10/94 (10%)
Query: 1393 NACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIY 1452
N C +NFD++G A++ +FQV T +GW+ IM +D+ + Y
Sbjct: 239 NECRAGEINPHKGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAH----------SFY 288
Query: 1453 MYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
++Y +NL + VI F+E K++
Sbjct: 289 NFIYFIFLIIVGSFFMINLCLVVIATQFSETKQR 322
Score = 46.0 bits (104), Expect = 0.011
Identities = 30/96 (31%), Positives = 51/96 (53%), Gaps = 4/96 (4%)
Query: 835 VFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPD 894
V KL K + L+ + + + +GNL + ++ FI+A +G++LFGK ++ D P
Sbjct: 1483 VLKLLKMATGMRALLDTVIQALPQVGNLGLLFMLLFFIYAALGVELFGK--LECSDNNPC 1540
Query: 895 GDLPRW-NFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
L R F +F +F+ +FRV G+ W M D +
Sbjct: 1541 EGLSRHATFDNFGMAFLTLFRVSTGDNWNGIMKDTL 1576
Score = 45.2 bits (102), Expect = 0.018
Identities = 19/70 (27%), Positives = 42/70 (60%), Gaps = 11/70 (15%)
Query: 349 NPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVN 397
NP+ G +FD G+A+++ F+++T + W ++ ++F+ +I +GSF+++N
Sbjct: 247 NPHKGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFIFLIIVGSFFMIN 306
Query: 398 LILAIVAMSY 407
L L ++A +
Sbjct: 307 LCLVVIATQF 316
Score = 40.7 bits (91), Expect = 0.40
Identities = 35/136 (25%), Positives = 63/136 (46%), Gaps = 10/136 (7%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL----RYH 1593
F+ + +L I LN +T+ + +Q +L L+ V F+ E ++K+ AL +
Sbjct: 5 FERVSILAILLNCVTLGM--FQPCGHTPFLLQALDDGIFVFFAGEMVVKMVALGVIGQSG 62
Query: 1594 YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRT 1653
Y + WN DF +V+ +L L + + VS + +R VRV + R + V +
Sbjct: 63 YLGDTWNRLDFFIVIVGMLEYSL----DGHNVSLSAIRTVRVLRPLRAINRVPMTVPLAY 118
Query: 1654 LLFALAMSLPALFNIC 1669
L+ + + NIC
Sbjct: 119 YLYRFSCYFEVVINIC 134
Score = 37.9 bits (84), Expect = 2.8
Identities = 16/54 (29%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF-GKNY 885
LR ++ P L L++ + ++ +GN+ + C +F ++G+QLF GK Y
Sbjct: 1140 LRPLRVISRAPGLKLVVETLITSLRPIGNIVLICCAFFIVFGILGVQLFKGKFY 1193
Score = 37.5 bits (83), Expect = 3.7
Identities = 15/38 (39%), Positives = 26/38 (68%)
Query: 796 FVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYL 833
+++LFIT+ I N L M+++H+N K ++ LK NY+
Sbjct: 1348 YLDLFITIIIFTNLLTMSMEHYNQPKYFEEILKYCNYV 1385
Score = 36.7 bits (81), Expect = 6.4
Identities = 19/63 (30%), Positives = 37/63 (58%), Gaps = 11/63 (17%)
Query: 356 SFDTFGWAFLSAFRLMTQDYWEN-LYQ----------LFFVVIIFLGSFYLVNLILAIVA 404
+FD+ WA ++ F+++TQ+ W + LY L+FV ++ G++ L NL++AI+
Sbjct: 648 NFDSLLWATVTVFQILTQEDWNSVLYNGMASTTPLAALYFVALMTFGNYVLFNLLVAILV 707
Query: 405 MSY 407
+
Sbjct: 708 EGF 710
>UniRef50_A0DRJ4 Cluster: Chromosome undetermined scaffold_60, whole
genome shotgun sequence; n=4; Eukaryota|Rep: Chromosome
undetermined scaffold_60, whole genome shotgun sequence -
Paramecium tetraurelia
Length = 2176
Score = 256 bits (627), Expect = 4e-66
Identities = 181/631 (28%), Positives = 314/631 (49%), Gaps = 49/631 (7%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEM 1267
R ++ +++ F+ ++ +IL+SS L L+ L + + Y++D ++F E
Sbjct: 1346 RKMCYRAVKDKIFDIIILILILISSAKLILDTYTLGNS--YDVVSYWLDFSMVILFGCEA 1403
Query: 1268 LIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRP 1323
L+K +A GF Y N+W LDFII++ S+++ A A + K +R R LRP
Sbjct: 1404 LLKIIAFGFIGDDLSYLRNSWNALDFIILIGSIVDISVA---AIDLSYLKILRLFRTLRP 1460
Query: 1324 LRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTT 1383
LR +S + M+++V+AL+Q+ I NV +V ++ W++FAI+G+ GK + C DM
Sbjct: 1461 LRFVSHNRSMKIIVSALLQSADGILNVAIVIILVWMMFAIIGINFAKGKLYYC-DMGDGA 1519
Query: 1384 LSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGR 1443
+ H + K C W NF+++ L LF ++T W + D E G
Sbjct: 1520 M-HYVT--KAEC---EGVWRIYDSNFENIFSGMLTLFCLSTLLDWPDQLLYFKDGTENGL 1573
Query: 1444 QPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYY 1503
+++++ +L+ NLFIGVI+ NF+ ++KA S +T+DQ ++
Sbjct: 1574 --VKDSSPEFFLFFLAFILIGSILLNNLFIGVILVNFHIAEEKARDSS---LTQDQIQWI 1628
Query: 1504 NAMKKMGSKKP-LKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSE 1562
+ K + KP L P+ R QA +F IV + FD+II LFI +N++ +
Sbjct: 1629 DTQKLIIEAKPDLSLYYMPKNRIQAFLFRIVKARNFDLIISLFIIINIVVTGMYMDDGDL 1688
Query: 1563 TFSAVLDYLNMIFIVIFSSECLLKIFALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIE 1621
+ V+D +N +IF E ++KI YF WN FDFV+V+ SI+ ++
Sbjct: 1689 EYLYVIDQINFAISIIFCFEAIIKIITFGPLAYFKVNWNQFDFVIVVISIIDFATNES-- 1746
Query: 1622 KYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAI 1681
++ + R+ + R+LRLVK KG++ L+ S+PA+ N L FL+ IF++
Sbjct: 1747 ----GLSIGKGFRILRAVRLLRLVKQFKGLKKLIDTAVFSIPAIINAAALYFLIHSIFSV 1802
Query: 1682 FGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNER 1741
G+ F +K+ + D NF+ F S ILLF T W+ ++ +N
Sbjct: 1803 LGVFLFSDIKEGKIISDTNNFQDFHHSFILLFLSQTGLDWNRIMYDTMN----------N 1852
Query: 1742 GSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENY--SQATEDVQEGLTDDDYDMY 1799
GS N + + +++I +++N++I ++L+ Y + ED D+ +
Sbjct: 1853 GSQYNA-------LFWVVFILIQNFVMLNLFILIVLDQYDVNYFHEDNPLNRFDEYQNKT 1905
Query: 1800 YEIWQRFDPDGSQYIRYDQLSDFLDVLEPPL 1830
++W RF DG+ I ++L+D + L PL
Sbjct: 1906 LDVWTRFSQDGA-IINQNKLTDLILALPKPL 1935
Score = 105 bits (253), Expect = 9e-21
Identities = 53/167 (31%), Positives = 98/167 (58%), Gaps = 5/167 (2%)
Query: 127 FNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVM 186
F +R + Y++ F L ++ I++N + + + V+ E+IF Y+ E+ K++
Sbjct: 114 FQSVRYLMKYLINLKFFQLILMVIIILNSLCLALE----VDQYEIIFIICYSVEAIFKML 169
Query: 187 ARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLG-NLAALRTFRVLRALKTVAIVPGL 245
A G + +Y RD WN +DFV++ Y+ +++ N ALRT R+LR+L +P L
Sbjct: 170 ALGLYSKRDSYFRDFWNVIDFVILVFQYLPYFVNIQFNFNALRTIRILRSLDAGQSIPAL 229
Query: 246 KTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKV 292
K I+ ++ +SV L+D +I+ +FS S+FA++ L ++ G L ++CV +
Sbjct: 230 KVILTSLFQSVYQLKDALIVLVFSYSIFAIVALLLFSGGLKRRCVNL 276
Score = 90.6 bits (215), Expect = 4e-16
Identities = 141/648 (21%), Positives = 275/648 (42%), Gaps = 114/648 (17%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEM 1267
R+K LI++ YF + + +++ LAL+ + + + +L D+ + FT+IF IE+
Sbjct: 1029 RVKLQNLIQSEYFNRLINFCVACNTIVLALDGL-VTNDKLLSDL----NLAFTIIFIIEL 1083
Query: 1268 LIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAG--GIQAFKTMRTLRALRPLR 1325
K + LG + Y + + D +IV +SL + G G A +++R RALR LR
Sbjct: 1084 GFKLIGLGVKGYVQDKFNLFDALIVGISLYEVIINQENGGKSGFSALRSLRIFRALRVLR 1143
Query: 1326 AMSRMQGMRVV---VNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHT 1382
++ ++ + + L A I + ++ L F F I+G LF G+
Sbjct: 1144 ISKLIRSLKFMGFLLKVLGNAFEQILWMFILMLFFLYTFTILGFSLFQGE---------- 1193
Query: 1383 TLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVG 1442
I D+N YT+ + ++F+ V FQ+ T W ++ S
Sbjct: 1194 ------ISDEN----YRYTFNSFIISFETV-------FQLFTISNWSDVLYSLFLS---- 1232
Query: 1443 RQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKY 1502
NI ++LY LNLF+ V++DNF + ++ ++ + + +
Sbjct: 1233 ----NANNIVVFLYLVLWIAIGNYIFLNLFLAVLLDNFEAEYRRDKNQIDNNIIIGRDQI 1288
Query: 1503 YN---AMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIG-LNMLTMTLDHY 1558
+ + K GS+K K+ + ++ + ++F I ++ ++ +
Sbjct: 1289 FESAISSKPQGSRKSSKS----SLQDDVEEYQKLQTQRFIYFSERGIAEFALMVLSQESA 1344
Query: 1559 QQSETFSAV----LDYLNMIFIVIFSSECLLKIFALRYHY-FVEPWNLFDFVVV-----M 1608
+ + AV D + +I I+I S++ +L + L Y V W F V++ +
Sbjct: 1345 FRKMCYRAVKDKIFDIIILILILISSAKLILDTYTLGNSYDVVSYWLDFSMVILFGCEAL 1404
Query: 1609 FSILS--------------------LVLSDIIEKYFVSPTLLRVVRVAKVGRVL---RLV 1645
I++ ++L I V+ L +++ ++ R L R V
Sbjct: 1405 LKIIAFGFIGDDLSYLRNSWNALDFIILIGSIVDISVAAIDLSYLKILRLFRTLRPLRFV 1464
Query: 1646 KGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSF-------------FMHVKD 1692
+ ++ ++ AL S + N+ +++ LV +FAI G++F MH
Sbjct: 1465 SHNRSMKIIVSALLQSADGILNVAIVIILVWMMFAIIGINFAKGKLYYCDMGDGAMHYVT 1524
Query: 1693 KGGLDDVY-----NFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNC 1747
K + V+ NF+ M+ LF +ST W D ++ ++ E G +
Sbjct: 1525 KAECEGVWRIYDSNFENIFSGMLTLFCLSTLLDWP---DQLLYFKD----GTENGLVKD- 1576
Query: 1748 GSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQE-GLTDD 1794
S+ + L++++I +++ N++I VIL N+ A E ++ LT D
Sbjct: 1577 -SSPEFFLFFLAFILIGSILLNNLFIGVILVNFHIAEEKARDSSLTQD 1623
Score = 84.6 bits (200), Expect = 2e-14
Identities = 58/205 (28%), Positives = 106/205 (51%), Gaps = 14/205 (6%)
Query: 91 EDIDPFYHNQTTFVVISKGKDIFRFSATNALWILDPFNPIRRVAIYILVHPLFSLFIITT 150
+D++ + QT + + I F AL +L + R++ + +F + I+
Sbjct: 1310 DDVEEYQKLQTQRFIYFSERGIAEF----ALMVLSQESAFRKMCYRAVKDKIFDIIILIL 1365
Query: 151 ILVNCILMIMPTTPTVESTEVI-----FTGIYTF--ESAVKVMARGFILQPFTYLRDAWN 203
IL++ +I+ T S +V+ F+ + F E+ +K++A GFI +YLR++WN
Sbjct: 1366 ILISSAKLILDTYTLGNSYDVVSYWLDFSMVILFGCEALLKIIAFGFIGDDLSYLRNSWN 1425
Query: 204 WLDFVVIALAYVTM---GIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLR 260
LDF+++ + V + IDL L LR FR LR L+ V+ +K IV A+++S +
Sbjct: 1426 ALDFIILIGSIVDISVAAIDLSYLKILRLFRTLRPLRFVSHNRSMKIIVSALLQSADGIL 1485
Query: 261 DVIILTMFSLSVFALMGLQIYMGVL 285
+V I+ + +FA++G+ G L
Sbjct: 1486 NVAIVIILVWMMFAIIGINFAKGKL 1510
Score = 75.4 bits (177), Expect = 2e-11
Identities = 70/282 (24%), Positives = 132/282 (46%), Gaps = 39/282 (13%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
LI +F+ ++ +I+L+SL LALE + + IF + + +E + K LA
Sbjct: 124 LINLKFFQLILMVIIILNSLCLALE-------------VDQYEIIFIICYSVEAIFKMLA 170
Query: 1274 LGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQ-AFKTMRTLRALRPLRAMS 1328
LG YF + W +DF+I++ + + IQ F +RT+R LR L A
Sbjct: 171 LGLYSKRDSYFRDFWNVIDFVILVFQYLPYFV------NIQFNFNALRTIRILRSLDAGQ 224
Query: 1329 RMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKCVDM-NHTTLSH 1386
+ ++V++ +L Q++ + + L+V + + IFAI+ + LF+G +CV++ ++
Sbjct: 225 SIPALKVILTSLFQSVYQLKDALIVLVFSYSIFAIVALLLFSGGLKRRCVNLETGIPRNN 284
Query: 1387 EIIPD---KNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGR 1443
E+ + + C + NS +NFD G + + +F + W QI++
Sbjct: 285 EVCSECQGEFECVKQIANPFNSLINFDTFGWSLIQVFICTLLESWSQILD---------- 334
Query: 1444 QPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKK 1485
+ N +Y+Y +NL + +I NF+ +K
Sbjct: 335 YTVAAYNEAVYIYFFMVVMVGGFFLVNLTLAIIKLNFSNNQK 376
Score = 60.1 bits (139), Expect = 6e-07
Identities = 36/155 (23%), Positives = 77/155 (49%), Gaps = 10/155 (6%)
Query: 142 LFSLFIITTILVNCILMI---MPTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYL 198
+ SLFII I+V + M + ++ + I+ FE+ +K++ G P Y
Sbjct: 1667 IISLFIIINIVVTGMYMDDGDLEYLYVIDQINFAISIIFCFEAIIKIITFG----PLAYF 1722
Query: 199 RDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIV---PGLKTIVGAVIES 255
+ WN DFV++ ++ + + L+ + FR+LRA++ + +V GLK ++ + S
Sbjct: 1723 KVNWNQFDFVIVVISIIDFATNESGLSIGKGFRILRAVRLLRLVKQFKGLKKLIDTAVFS 1782
Query: 256 VKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCV 290
+ + + L S+F+++G+ ++ + K +
Sbjct: 1783 IPAIINAAALYFLIHSIFSVLGVFLFSDIKEGKII 1817
Score = 51.2 bits (117), Expect = 3e-04
Identities = 43/161 (26%), Positives = 79/161 (49%), Gaps = 24/161 (14%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL- 1590
++ K F +I+M+ I LN L + L+ +D +IFI+ +S E + K+ AL
Sbjct: 124 LINLKFFQLILMVIIILNSLCLALE-----------VDQYEIIFIICYSVEAIFKMLALG 172
Query: 1591 ----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVK 1646
R YF + WN+ DFV+++F L ++ I+ F + +R++R G+ +
Sbjct: 173 LYSKRDSYFRDFWNVIDFVILVFQYLPYFVN--IQFNFNALRTIRILRSLDAGQSI---- 226
Query: 1647 GAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
++ +L +L S+ L + ++L IFAI + F
Sbjct: 227 --PALKVILTSLFQSVYQLKDALIVLVFSYSIFAIVALLLF 265
Score = 39.1 bits (87), Expect = 1.2
Identities = 40/169 (23%), Positives = 75/169 (44%), Gaps = 15/169 (8%)
Query: 784 FQKYVALLVFDPFVEL------FITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFK 837
F+ + ++ F P F + +V++ + A + + + K + +R+ +
Sbjct: 1707 FEAIIKIITFGPLAYFKVNWNQFDFVIVVISIIDFATNESGLS--IGKGFRILRAVRLLR 1764
Query: 838 LAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDL 897
L K + L LI ++ A+ N + +I IF+V+G+ LF D + D
Sbjct: 1765 LVKQFKGLKKLIDTAVFSIPAIINAAALYFLIHSIFSVLGVFLFS----DIKEGKIISDT 1820
Query: 898 PRWNFTDFMHSFMIVFRVLCG-EWIESMWDCMLVGDVSCIPFFLATVVI 945
NF DF HSF+++F G +W M+D M G F++ ++I
Sbjct: 1821 N--NFQDFHHSFILLFLSQTGLDWNRIMYDTMNNGSQYNALFWVVFILI 1867
Score = 38.7 bits (86), Expect = 1.6
Identities = 30/127 (23%), Positives = 66/127 (51%), Gaps = 15/127 (11%)
Query: 173 FTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN-----LAAL 227
FT I+ E K++ G Y++D +N D +++ ++ + I+ N +AL
Sbjct: 1075 FTIIFIIELGFKLIGLGVK----GYVQDKFNLFDALIVGISLYEVIINQENGGKSGFSAL 1130
Query: 228 RTFRVLRALKTVAIVPGLKTI--VGAVIESVKNLRDVI----ILTMFSLSVFALMGLQIY 281
R+ R+ RAL+ + I ++++ +G +++ + N + I IL +F L F ++G ++
Sbjct: 1131 RSLRIFRALRVLRISKLIRSLKFMGFLLKVLGNAFEQILWMFILMLFFLYTFTILGFSLF 1190
Query: 282 MGVLTQK 288
G ++ +
Sbjct: 1191 QGEISDE 1197
>UniRef50_A4RW52 Cluster: VIC family transporter: calcium ion channel;
n=1; Ostreococcus lucimarinus CCE9901|Rep: VIC family
transporter: calcium ion channel - Ostreococcus
lucimarinus CCE9901
Length = 938
Score = 255 bits (625), Expect = 8e-66
Identities = 173/598 (28%), Positives = 302/598 (50%), Gaps = 35/598 (5%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+R F LI++ FE ++ +I+ S + LAL+ + L +L D FT+IF E
Sbjct: 320 MRRLLFMLIKHPAFEALMLVLIVFSCIQLALDAPTVHPESDLASVLKAADVSFTLIFLGE 379
Query: 1267 MLIKWLALGFQK----YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALR 1322
+IK +A+GF Y + DF IV+VSL A +++ ++ R RALR
Sbjct: 380 AIIKVIAMGFVMHPGAYLRSPANCFDFFIVIVSL---AVETMSASALKSMRSFRLFRALR 436
Query: 1323 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHT 1382
PLR ++R++ M++VV L+ +P + +V+L+ L +LIFAI+G QLFAGK+ C D +
Sbjct: 437 PLRLLNRVKSMQIVVATLLHVLPDLGSVMLLGLFQFLIFAILGSQLFAGKFDYCNDPTVS 496
Query: 1383 TLS---HEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSR 1439
+ + +K A W N P+NFD+ A L LF + T GW+ + +DS
Sbjct: 497 GMHACVGTFVDEKGAHVTRR--WLNPPLNFDNTLLALLSLFVIVTRDGWLSVAFQGMDST 554
Query: 1440 EVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQ 1499
+ QP + + +Y L++ + ++ +++ +K + + +Q
Sbjct: 555 DTDLQPSLNNSGWTAIYFLSFIVILSFVWLSMIVALVCESY--KKACVLSNSTQTLNAEQ 612
Query: 1500 KKYYNAMKKMGSKKPLKAIP-----RPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMT 1554
+++ ++ LK + PR+ + + + T+ +F+ I+ I N +TM
Sbjct: 613 QEWAEVLRMKKHDAELKILDDDTTGAPRFFIRKSAYSLATNPRFEAFIVGCIIANTITMA 672
Query: 1555 LDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL-RYHYFVEPWNLFDFVVVMFSILS 1613
H Q + ++ + N+ F IF E LK+ AL YF E WN+FDF++V+ SI
Sbjct: 673 SYHDGQPKAYAEIQRAANVFFSWIFLLELSLKMVALFPKRYFSERWNVFDFIIVVASIPD 732
Query: 1614 LVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLF 1673
L D F T+LRV+R +GR LRL K AKG+RT+ L S + FN+ L+F
Sbjct: 733 LAGVD-----FAGTTVLRVIR---LGRALRLFKQAKGLRTVFNTLLSSFESAFNVVFLIF 784
Query: 1674 LVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEE 1733
++MF++A+ GM+ F + V NF+ F S+++L ++ T W ++ + +
Sbjct: 785 MLMFVYAVLGMNLFGDYETTYPSGRVENFRNFGASLMVLLRVITRDNWKRIM---FDTMK 841
Query: 1734 CDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGL 1791
C+ N G NC + + S++++ +++++ IA IL+ +++ V EGL
Sbjct: 842 CEY--NVDGVAANCSYIFVPALFFTSFILLGAYVLLSLIIASILDKFTE--NAVNEGL 895
Score = 95.1 bits (226), Expect = 2e-17
Identities = 53/176 (30%), Positives = 98/176 (55%), Gaps = 12/176 (6%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM--PTT-------PTVESTE 170
+L + P P+RR+ ++ HP F ++ I+ +CI + + PT +++ +
Sbjct: 310 SLGFIKPRRPMRRLLFMLIKHPAFEALMLVLIVFSCIQLALDAPTVHPESDLASVLKAAD 369
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDF--VVIALAYVTMGID-LGNLAAL 227
V FT I+ E+ +KV+A GF++ P YLR N DF V+++LA TM L ++ +
Sbjct: 370 VSFTLIFLGEAIIKVIAMGFVMHPGAYLRSPANCFDFFIVIVSLAVETMSASALKSMRSF 429
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
R FR LR L+ + V ++ +V ++ + +L V++L +F +FA++G Q++ G
Sbjct: 430 RLFRALRPLRLLNRVKSMQIVVATLLHVLPDLGSVMLLGLFQFLIFAILGSQLFAG 485
Score = 72.9 bits (171), Expect = 8e-11
Identities = 52/194 (26%), Positives = 89/194 (45%), Gaps = 17/194 (8%)
Query: 1533 VTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY 1592
V K F+ I I +N + + + ++ LN + + +F E ++K+ A
Sbjct: 3 VKHKYFENGITSAIVVNTIILAVHFRGMGSEMETAVNNLNYLLLSVFVFELVMKVLAFGI 62
Query: 1593 -HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGI 1651
Y + +NLFD VV ++ L + S + R R+ +V R RL+ K +
Sbjct: 63 LGYSKDRYNLFDATVVTAGLIELAYRNS------SLAVARAFRLLRVMRTTRLITRNKNM 116
Query: 1652 RTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVY----NFKTFVQ 1707
R L+ S A+ N C +LF+ +F+F + GM F GG D+ + NF TF
Sbjct: 117 RRLIDTTMESFSAILNFCGVLFVFVFVFTVLGMQLF------GGRDEFWDARPNFNTFGD 170
Query: 1708 SMILLFQMSTSAGW 1721
S + +F++ T + W
Sbjct: 171 SFLSVFEILTGSHW 184
Score = 68.5 bits (160), Expect = 2e-09
Identities = 42/160 (26%), Positives = 78/160 (48%), Gaps = 12/160 (7%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMI-----MPTT--PTVESTEVIFTGIYTFESA 182
IR+ A + +P F FI+ I+ N I M P + V F+ I+ E +
Sbjct: 643 IRKSAYSLATNPRFEAFIVGCIIANTITMASYHDGQPKAYAEIQRAANVFFSWIFLLELS 702
Query: 183 VKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM-GIDLGNLAALRTFRVLRALKTVAI 241
+K++A L P Y + WN DF+++ + + G+D LR R+ RAL+
Sbjct: 703 LKMVA----LFPKRYFSERWNVFDFIIVVASIPDLAGVDFAGTTVLRVIRLGRALRLFKQ 758
Query: 242 VPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
GL+T+ ++ S ++ +V+ L + V+A++G+ ++
Sbjct: 759 AKGLRTVFNTLLSSFESAFNVVFLIFMLMFVYAVLGMNLF 798
Score = 64.5 bits (150), Expect = 3e-08
Identities = 37/158 (23%), Positives = 80/158 (50%), Gaps = 5/158 (3%)
Query: 1215 IENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLAL 1274
+++ YFE + + I+++++ LA+ + ++ + ++ + +F E+++K LA
Sbjct: 3 VKHKYFENGITSAIVVNTIILAVHFRGMGSE--METAVNNLNYLLLSVFVFELVMKVLAF 60
Query: 1275 GFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMR 1334
G Y + + D +V LI +AF R LR +R R ++R + MR
Sbjct: 61 GILGYSKDRYNLFDATVVTAGLIELAYRNSSLAVARAF---RLLRVMRTTRLITRNKNMR 117
Query: 1335 VVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGK 1372
+++ +++ +I N V +F +F ++G+QLF G+
Sbjct: 118 RLIDTTMESFSAILNFCGVLFVFVFVFTVLGMQLFGGR 155
Score = 55.6 bits (128), Expect = 1e-05
Identities = 36/106 (33%), Positives = 61/106 (57%), Gaps = 12/106 (11%)
Query: 825 KALKSGNYLRVFKLAKSWPTL-NLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGK 883
+ ++ G LR+FK AK T+ N L+S + + N+ F++ +++F++AV+GM LFG
Sbjct: 745 RVIRLGRALRLFKQAKGLRTVFNTLLS----SFESAFNVVFLIFMLMFVYAVLGMNLFG- 799
Query: 884 NYVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
DY +P G + NF +F S M++ RV+ + W M+D M
Sbjct: 800 ---DYETTYPSGRVE--NFRNFGASLMVLLRVITRDNWKRIMFDTM 840
Score = 52.8 bits (121), Expect = 9e-05
Identities = 34/154 (22%), Positives = 71/154 (46%), Gaps = 14/154 (9%)
Query: 140 HPLFSLFIITTILVNCILMIM-------PTTPTVESTEVIFTGIYTFESAVKVMARGFIL 192
H F I + I+VN I++ + V + + ++ FE +KV+A G +
Sbjct: 5 HKYFENGITSAIVVNTIILAVHFRGMGSEMETAVNNLNYLLLSVFVFELVMKVLAFGIL- 63
Query: 193 QPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIV---PGLKTIV 249
Y +D +N D V+ + + +LA R FR+LR ++T ++ ++ ++
Sbjct: 64 ---GYSKDRYNLFDATVVTAGLIELAYRNSSLAVARAFRLLRVMRTTRLITRNKNMRRLI 120
Query: 250 GAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
+ES + + + + VF ++G+Q++ G
Sbjct: 121 DTTMESFSAILNFCGVLFVFVFVFTVLGMQLFGG 154
Score = 49.2 bits (112), Expect = 0.001
Identities = 37/120 (30%), Positives = 54/120 (45%), Gaps = 9/120 (7%)
Query: 806 VVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFV 865
VV + L + N + +A + +R +L + LI + A+ N V
Sbjct: 77 VVTAGLIELAYRNSSLAVARAFRLLRVMRTTRLITRNKNMRRLIDTTMESFSAILNFCGV 136
Query: 866 LCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCG-EWIESM 924
L + +F+F V+GMQLFG D F D R NF F SF+ VF +L G W + M
Sbjct: 137 LFVFVFVFTVLGMQLFGGR-----DEFWDA---RPNFNTFGDSFLSVFEILTGSHWYKLM 188
Score = 39.9 bits (89), Expect = 0.69
Identities = 23/60 (38%), Positives = 34/60 (56%), Gaps = 12/60 (20%)
Query: 356 SFDTFGWAFLSAFRLMTQDYWENLY------------QLFFVVIIFLGSFYLVNLILAIV 403
+F+TFG +FLS F ++T +W L LFF+ F+GSF L+NLI A++
Sbjct: 164 NFNTFGDSFLSVFEILTGSHWYKLMLVAMSGSYGAPAALFFICWSFIGSFVLLNLIAAML 223
>UniRef50_Q4S7Y3 Cluster: Chromosome 9 SCAF14710, whole genome shotgun
sequence; n=3; Eukaryota|Rep: Chromosome 9 SCAF14710,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 2340
Score = 244 bits (598), Expect = 1e-62
Identities = 196/686 (28%), Positives = 332/686 (48%), Gaps = 87/686 (12%)
Query: 1206 TLRLKTFKLIENTYFETAVITMILLSSLALALEDV--HLPHR-----------------P 1246
T R+ KLI + F ++ I+LSS++LA ED + R
Sbjct: 879 TFRVFCHKLINHQIFTNLILVFIMLSSVSLAAEDPIRNFSARNIILGYFDYAFTAIFTVE 938
Query: 1247 ILQDILYYMDRIFTVIFFIEMLIKWLALG--FQK--YFTNAWCWLDFIIVMVSLINFVAA 1302
IL IL Y D +FT +F E+LIK A G K + N + LD ++V VSL++F
Sbjct: 939 ILLKILGYADYVFTSMFTFEILIKMTAFGAFLHKGAFCRNYFNLLDLLVVGVSLVSFGIQ 998
Query: 1303 LCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFA 1362
+ I K +R LR LRPLRA++R +G++ VV + AI +I N+++V + +FA
Sbjct: 999 ---SSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFA 1055
Query: 1363 IMGVQLFAGKYFKCVDMNHTTLSH---EIIPDKNACT----LENYTWENSPMNFDHVGKA 1415
+GVQLF GK+++C D ++ I N T ++ W NS NFD+V A
Sbjct: 1056 CIGVQLFKGKFYRCTDDAKSSPEECKGTYILYNNGDTAPPMVKERIWYNSDFNFDNVLMA 1115
Query: 1416 YLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGV 1475
+ LF V+TF+GW ++ AIDS + PI I + ++ +N+F+G
Sbjct: 1116 MMALFTVSTFEGWPTLLYKAIDSNKENMGPIYNYRIEISIFFIIYIIIIAFFMMNIFVGF 1175
Query: 1476 IIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKA-IPRPRWRPQAIVFEIVT 1534
+I F EQ +K + E+ + Q Y A+K +PL+ IP+ + Q + +V
Sbjct: 1176 VIVTFQEQGEKEYKNCELDKNQRQCVEY-ALKA----RPLRRYIPKNPY--QYKFWYVVN 1228
Query: 1535 DKKFDMIIMLFIGLNMLTMTLDHYQQSE-----------TFSAVLDYLNMIFIVIFSS-- 1581
F+ ++ + I LN L + + H+ QS F+ V ++ ++ F
Sbjct: 1229 STGFEYVMFILIILNTLCLAIQHHGQSHLFNYAMDILNMVFTGVFTVEMILKLIAFKPRG 1288
Query: 1582 ---------ECLLKI-----FALRYHYFVEPWNLFDFVVVMFSILSLVLSDI------IE 1621
+ L+ I L +YF + WN FD ++V+ S++ + +++I +
Sbjct: 1289 YVGDPWNVFDALVVIGSVVDIILSQNYFADAWNTFDALIVVGSVVDIAITEINSATIPVV 1348
Query: 1622 KYFVSP--------TLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLF 1673
K V P + R+ +V R+++L+ +GIRTLL+ S AL + LL+
Sbjct: 1349 KVIVDPGNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIA 1408
Query: 1674 LVMFIFAIFGMSFFMHVKDKGG--LDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINE 1731
++ FI+A+ GM F + G ++ NF+TF Q++++LF+ +T W ++ +
Sbjct: 1409 MLFFIYAVIGMQVFGKIAMVDGTQINRNNNFQTFPQAVLMLFRCATGEAWQEIMLACLPG 1468
Query: 1732 EECDLP-DNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEG 1790
+ CD D G CGS I Y +S+ ++ ++IN+++AVI++N+ T D
Sbjct: 1469 KLCDSESDYNPGEERTCGSG-FAIFYFISFYMLCAFLIINLFVAVIMDNFDYLTRD-WSI 1526
Query: 1791 LTDDDYDMYYEIWQRFDPDGSQYIRY 1816
L D + IW +DP+ I++
Sbjct: 1527 LGPHHLDEFKRIWSEYDPEAKGRIKH 1552
Score = 105 bits (252), Expect = 1e-20
Identities = 76/267 (28%), Positives = 137/267 (51%), Gaps = 51/267 (19%)
Query: 167 ESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVI-------ALAYVTMGI 219
E+ E F I+T E+ +K++A G ++ +Y+R+ WN LDFV++ AL +T
Sbjct: 150 ETVEYAFLIIFTIETFLKIIAYGLVMHQNSYVRNGWNLLDFVIVIIGLFSVALEMITKDA 209
Query: 220 DLG----------NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFS 269
D ++ ALR FRVLR L+ V+ VP L+ ++ ++I+++ L + +L +F
Sbjct: 210 DSSGQSGGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFV 269
Query: 270 LSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGN 329
+ ++A++GL++++G + C E GS F + E P +
Sbjct: 270 IIIYAVIGLELFIGKMHATC--YIKETGS-----------FAEEEPT--------PCAVS 308
Query: 330 SSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQD------YWEN----- 378
G G +C +G+ PN G T+FD F +A L+ F+ +T + YW N
Sbjct: 309 GHGRHCLLNGTICREGW-QGPNNGITNFDNFLFAMLTVFQCITMEGWTDVLYWMNDAMGF 367
Query: 379 -LYQLFFVVIIFLGSFYLVNLILAIVA 404
L ++FV ++ GSF+++NL+L +++
Sbjct: 368 ELPWVYFVSLVIFGSFFVLNLVLGVLS 394
Score = 83.8 bits (198), Expect = 4e-14
Identities = 73/261 (27%), Positives = 119/261 (45%), Gaps = 44/261 (16%)
Query: 1259 FTVIFFIEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALC---------- 1304
F +IF IE +K +A G Y N W LDF+IV++ L + +
Sbjct: 156 FLIIFTIETFLKIIAYGLVMHQNSYVRNGWNLLDFVIVIIGLFSVALEMITKDADSSGQS 215
Query: 1305 -GAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAI 1363
G G K +R R LRPLR +S + ++VV+N++++A+ + ++ L+ L +I+A+
Sbjct: 216 GGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAV 275
Query: 1364 MGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACT------LENYT-----WE---NSPMNF 1409
+G++LF GK + T E P A + L N T W+ N NF
Sbjct: 276 IGLELFIGKMHATCYIKETGSFAEEEPTPCAVSGHGRHCLLNGTICREGWQGPNNGITNF 335
Query: 1410 DHVGKAYLCLFQVATFKGWIQI---MNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXX 1466
D+ A L +FQ T +GW + MNDA+ ++Y
Sbjct: 336 DNFLFAMLTVFQCITMEGWTDVLYWMNDAMGFE------------LPWVYFVSLVIFGSF 383
Query: 1467 XTLNLFIGVIIDNFNEQKKKA 1487
LNL +GV+ F+++++KA
Sbjct: 384 FVLNLVLGVLSGEFSKEREKA 404
Score = 79.8 bits (188), Expect = 7e-13
Identities = 66/272 (24%), Positives = 134/272 (49%), Gaps = 44/272 (16%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVL--------------------DYLNMIFIV 1577
F ++++ + LN LT+ +HY Q + + V + N + +
Sbjct: 512 FYWLVIILVFLNTLTIASEHYNQPDWLTEVQGGSCSDPPAHRTHSQAQRCSEVANKVLLA 571
Query: 1578 IFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVA 1636
+F+ E L+K+++L YFV +N FD VV I+ +L +E +SP + V R
Sbjct: 572 MFTLEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGIVETIL---VELAIMSPLGISVFRCV 628
Query: 1637 KVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGL 1696
++ R+ ++ + + L+ +L S+ ++ ++ LLLFL + IF++ GM F K
Sbjct: 629 RLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLF---GGKFNF 685
Query: 1697 DDVY----NFKTFVQSMILLFQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSAT 1751
D+ F F Q+++ +FQ+ T W+ V+ DGI+ G P + G
Sbjct: 686 DETVTKRSTFDNFPQALLTVFQILTGEDWNTVMYDGIM----------AYGGPASSG-ML 734
Query: 1752 IGITYLLSYLVISFLIVINMYIAVILENYSQA 1783
+ I +++ ++ ++ I++N+++A+ ++N + A
Sbjct: 735 VSIYFIILFICGNY-ILLNVFLAIAVDNLADA 765
Score = 74.5 bits (175), Expect = 3e-11
Identities = 83/375 (22%), Positives = 155/375 (41%), Gaps = 60/375 (16%)
Query: 1166 VGADEDVVDDTPADCCPEQCYQKFPFLAGDDDSPFWQGWGTL-RLKTFKLIENTYFETAV 1224
V D D + CC C QK + S W+ W R K +++ F V
Sbjct: 461 VNTDNHAGADDKSSCCGPLC-QK---ITKSKFSRQWRRWNRFCRRKCRAAVKSVIFYWLV 516
Query: 1225 ITMILLSSLALALEDVHLP----------------HRPI--LQDILYYMDRIFTVIFFIE 1266
I ++ L++L +A E + P HR Q +++ +F +E
Sbjct: 517 IILVFLNTLTIASEHYNQPDWLTEVQGGSCSDPPAHRTHSQAQRCSEVANKVLLAMFTLE 576
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVA---ALCGAGGIQAFKTMRTLRALRP 1323
ML+K +LG Q YF + + D +V ++ + A+ GI F+ +R LR +
Sbjct: 577 MLVKMYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELAIMSPLGISVFRCVRLLRIFKV 636
Query: 1324 LRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTT 1383
R + + + V +L+ ++ SI ++LL+ +F +IF+++G+QLF GK+ + + T
Sbjct: 637 TRHWASLSNL---VASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKF----NFDETV 689
Query: 1384 LSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGR 1443
FD+ +A L +FQ+ T + W +M D I +
Sbjct: 690 TKRS--------------------TFDNFPQALLTVFQILTGEDWNTVMYDGI----MAY 725
Query: 1444 QPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYY 1503
+ + + +Y LN+F+ + +DN + + E E+ KK
Sbjct: 726 GGPASSGMLVSIYFIILFICGNYILLNVFLAIAVDNLADAESLNTAQKE---EEEAKKRR 782
Query: 1504 NAMKKMGSKKPLKAI 1518
N+ K + + ++ +
Sbjct: 783 NSAKDVSPENKVEPV 797
Score = 72.5 bits (170), Expect = 1e-10
Identities = 36/117 (30%), Positives = 68/117 (58%), Gaps = 3/117 (2%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA--- 226
+ +FT ++TFE +K+ A G L + R+ +N LD +V+ ++ V+ GI ++
Sbjct: 948 DYVFTSMFTFEILIKMTAFGAFLHKGAFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKI 1007
Query: 227 LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
LR RVLR L+ + GLK +V V +++ + +++I+T +FA +G+Q++ G
Sbjct: 1008 LRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKG 1064
Score = 60.1 bits (139), Expect = 6e-07
Identities = 31/95 (32%), Positives = 56/95 (58%), Gaps = 6/95 (6%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LR+FK+ + W +L+ L++ + +M ++ +L +L + I IF+++GMQLFG + F
Sbjct: 631 LRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKF-----NF 685
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWD 926
+ R F +F + + VF++L GE W M+D
Sbjct: 686 DETVTKRSTFDNFPQALLTVFQILTGEDWNTVMYD 720
Score = 59.3 bits (137), Expect = 1e-06
Identities = 40/127 (31%), Positives = 66/127 (51%), Gaps = 13/127 (10%)
Query: 1575 FIVIFSSECLLKIFA--LRYH---YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTL 1629
F++IF+ E LKI A L H Y WNL DFV+V+ + S+ L I + S
Sbjct: 156 FLIIFTIETFLKIIAYGLVMHQNSYVRNGWNLLDFVIVIIGLFSVALEMITKDADSSGQS 215
Query: 1630 --------LRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAI 1681
++ +R +V R LRLV G ++ +L ++ ++ L +I LL+ V+ I+A+
Sbjct: 216 GGKPGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAV 275
Query: 1682 FGMSFFM 1688
G+ F+
Sbjct: 276 IGLELFI 282
Score = 43.2 bits (97), Expect = 0.074
Identities = 32/123 (26%), Positives = 61/123 (49%), Gaps = 10/123 (8%)
Query: 167 ESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLD-FVVIALAYVTMGIDLGNLA 225
E + ++T E VK+ + G LQ Y +N D FVV T+ ++L ++
Sbjct: 563 EVANKVLLAMFTLEMLVKMYSLG--LQ--AYFVSLFNRFDCFVVCGGIVETILVELAIMS 618
Query: 226 AL-----RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
L R R+LR K L +V +++ S+K++ +++L + +F+L+G+Q+
Sbjct: 619 PLGISVFRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQL 678
Query: 281 YMG 283
+ G
Sbjct: 679 FGG 681
Score = 42.3 bits (95), Expect = 0.13
Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 5/97 (5%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
+R+ KL + L+ ++ AL + ++ ++ FI+AV+GMQ+FGK + VD
Sbjct: 1374 MRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGK--IAMVDGT 1431
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
NF F + +++FR GE W E M C+
Sbjct: 1432 QIN--RNNNFQTFPQAVLMLFRCATGEAWQEIMLACL 1466
Score = 37.9 bits (84), Expect = 2.8
Identities = 17/57 (29%), Positives = 36/57 (63%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
KAL++ LR +L P+L ++++ + + M L ++ ++ +I I+AV+G++LF
Sbjct: 225 KALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAVIGLELF 281
>UniRef50_Q4Q3G0 Cluster: Calcium channel protein, putative; n=3;
Leishmania|Rep: Calcium channel protein, putative -
Leishmania major
Length = 2555
Score = 239 bits (584), Expect = 7e-61
Identities = 174/650 (26%), Positives = 312/650 (48%), Gaps = 40/650 (6%)
Query: 1214 LIENTYFETAVITMILLSSLALAL-------EDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
++ + +FE AV+ ++ +S+ LA+ D + L+ +D IF++IF +E
Sbjct: 1585 VVGSMWFEIAVLCVVYAASIFLAVYAPDEGNRDFGGSYNSAKYKALHILDDIFSIIFAVE 1644
Query: 1267 MLIKWLALGF-----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRAL 1321
ML+KW+++G + YF + W DF IV++SL+++ ++ K MR R L
Sbjct: 1645 MLLKWISMGVVLPVGRAYFWHRWNIFDFFIVIISLVSWGKPDIF---LRYLKVMRCFRIL 1701
Query: 1322 RPLRAMS-RMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMN 1380
PLR M V + +IP++ NV L+ L+ ++++AI+ V LF K+ C
Sbjct: 1702 GPLRYWKWGSSSMSHVARTIWDSIPTLANVCLLMLMNYIVWAIIFVSLFMDKFNYC---- 1757
Query: 1381 HTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSRE 1440
S+ I + C E YTW + NF + ++ L F+++T WI ++ A+DSR
Sbjct: 1758 ----SNASIVNGTQCVEEGYTWAPTQRNFRNFYESLLTTFEISTGAEWIDVIYSAVDSRS 1813
Query: 1441 VGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQK 1500
P+R Y+ L LFI +I + K + T + +
Sbjct: 1814 ALLSPLRNQRPYLGLVFIAYYYVSHFIFFTLFISAVIYCYMLAKSATEDATGT--TIEHQ 1871
Query: 1501 KYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQ 1560
+ + KP + R +V +++++ F+ + L + NMLTM+L+ YQ
Sbjct: 1872 VWLRMQGMIFRLKPKVQLLPLNTRVSRLVHFLISNRWFEAFMGLILVFNMLTMSLEWYQM 1931
Query: 1561 SETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDII 1620
S T LD I++VIF+ E +L+ A +F +D ++V+ S + + LS
Sbjct: 1932 SSTQKTTLDAFQYIWVVIFTLEVVLRFVAHGLRFFTRRAYCWDLLIVVLSYIQIGLSTTA 1991
Query: 1621 EKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRT--LLF--ALAMSLPALFNICLLLFLVM 1676
+ P + V+R+ +VGRVL LV A T LF L S+P L ++ + + +
Sbjct: 1992 TNHV--PFNVNVLRMLRVGRVLHLVHLALPFSTHLTLFHEVLKASVPGLISVTFVYMIAV 2049
Query: 1677 FIFAIFGMSFFMH-VKDKGGLDDVY-NFKTFVQSMILLFQMSTSAGWDGVLDGIINEEEC 1734
++FAI G+ F + V G +DD Y NF TFV ++I++F++ST W +L G ++
Sbjct: 2050 YVFAILGLHFLGYIVPFSGYIDDKYNNFGTFVNALIMVFRLSTLQNWATMLRGSLDRGYY 2109
Query: 1735 DLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDD 1794
++R CG Y + ++ FL++ +Y+AV+L+ Y A D
Sbjct: 2110 CTRASKR-----CGPTDWAPVYYIPIVICFFLLLSTLYMAVVLDKYVTAVRIYSAVTRLD 2164
Query: 1795 DYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQI-HKPNKYKIISM 1843
+ + +W DP+G+ ++ L + L+ L PL + + N+ +++ +
Sbjct: 2165 ELRRFCRLWSTRDPNGTMWLPSAVLPELLEELRLPLGVSDRRNRVEVMQL 2214
Score = 97.1 bits (231), Expect = 4e-18
Identities = 72/243 (29%), Positives = 107/243 (44%), Gaps = 23/243 (9%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV--TMGIDLGNLAAL 227
+V +T + FE ++ A G IL + R W WLD V+ L+ + T DL N A
Sbjct: 183 DVFYTCLLGFEIIARLFASGGILHKRAFFRSPWRWLDTAVLVLSIMECTWWQDLWNFTAW 242
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQ 287
R R ++ L V +K + +++ S L V IL + + F L+GLQ++ G L
Sbjct: 243 RLIRTIKCLTYVPAPVRMKLLAKSLLRSTNRLIYVTILLTYFIFFFGLLGLQLFAGTLHS 302
Query: 288 KCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFG 347
+CV LT + C++ + GE G Y C Y C
Sbjct: 303 RCV---------NTLTGAVTSQVCRSVST--GEYGFY-------WGHHCGVFYTCQADAF 344
Query: 348 PNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQLF---FVVIIFLGSFYLVNLILAIVA 404
PNP+Y + SFD G A LS F++MT W L Q ++ FL F+ + + IV
Sbjct: 345 PNPHYDFRSFDDIGHAMLSVFQIMTFQGWSGLLQETNDGLAMMAFLYYFFTILVCTWIVP 404
Query: 405 MSY 407
Y
Sbjct: 405 SLY 407
Score = 56.4 bits (130), Expect = 7e-06
Identities = 57/261 (21%), Positives = 121/261 (46%), Gaps = 38/261 (14%)
Query: 1206 TLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLP-----HRPILQDILYYMDRIFT 1260
T R+ + ++ + E + MIL ++ A H H+P D + + D +T
Sbjct: 131 TPRVIVYNVMHHWLMEMFIFLMILSYAIFQATWGRHTAPPGGMHKP---DHIIWADVFYT 187
Query: 1261 VIFFIEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMR 1316
+ E++ + A G + +F + W WLD ++++S++ A++ +R
Sbjct: 188 CLLGFEIIARLFASGGILHKRAFFRSPWRWLDTAVLVLSIME-CTWWQDLWNFTAWRLIR 246
Query: 1317 TLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGK-YFK 1375
T++ L + A RM +++ +L+++ + V ++ F F ++G+QLFAG + +
Sbjct: 247 TIKCLTYVPAPVRM---KLLAKSLLRSTNRLIYVTILLTYFIFFFGLLGLQLFAGTLHSR 303
Query: 1376 CVDMNHTTLSHEIIPDKNACTLE-NYTWEN--------------SP----MNFDHVGKAY 1416
CV+ ++ ++ ++ T E + W + +P +FD +G A
Sbjct: 304 CVNTLTGAVTSQVC--RSVSTGEYGFYWGHHCGVFYTCQADAFPNPHYDFRSFDDIGHAM 361
Query: 1417 LCLFQVATFKGWIQIMNDAID 1437
L +FQ+ TF+GW ++ + D
Sbjct: 362 LSVFQIMTFQGWSGLLQETND 382
Score = 42.7 bits (96), Expect = 0.098
Identities = 30/122 (24%), Positives = 57/122 (46%), Gaps = 7/122 (5%)
Query: 1259 FTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTL 1318
F+V+F +E+LI+ LALG +FT+ ++ ++ SL F F +R L
Sbjct: 930 FSVLFMLELLIRLLALGPGPFFTDILILIEATFMVTSL--FQLGYSRTNTTSLFNWVRFL 987
Query: 1319 RALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD 1378
R R + + +R V L+ P + L++ ++ ++ ++G+ F G +D
Sbjct: 988 RLFRVIPC----RPLRRVSRVLIHGFPDMVYALVLFTLYMFMWLLLGMSFF-GSRIGWID 1042
Query: 1379 MN 1380
N
Sbjct: 1043 YN 1044
Score = 42.7 bits (96), Expect = 0.098
Identities = 42/155 (27%), Positives = 75/155 (48%), Gaps = 17/155 (10%)
Query: 142 LFSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDA 201
L +F + T+ + M T+++ + I+ I+T E ++ +A G L+ FT R A
Sbjct: 1915 LILVFNMLTMSLEWYQMSSTQKTTLDAFQYIWVVIFTLEVVLRFVAHG--LRFFT--RRA 1970
Query: 202 WNWLDFVVIALAYVTMGIDLG-------NLAALRTFRVLRALKTVAIVPGLKTIVGAVIE 254
+ W D +++ L+Y+ +G+ N+ LR RV R L V + T + E
Sbjct: 1971 YCW-DLLIVVLSYIQIGLSTTATNHVPFNVNVLRMLRVGRVLHLVHLALPFSTHLTLFHE 2029
Query: 255 ----SVKNLRDVIILTMFSLSVFALMGLQIYMGVL 285
SV L V + M ++ VFA++GL ++G +
Sbjct: 2030 VLKASVPGLISVTFVYMIAVYVFAILGLH-FLGYI 2063
Score = 41.9 bits (94), Expect = 0.17
Identities = 38/182 (20%), Positives = 80/182 (43%), Gaps = 21/182 (11%)
Query: 122 WILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTP----------------T 165
++L P NP+RRV ++ F + ++ + I + +
Sbjct: 1570 FVLSPSNPVRRVVSAVVGSMWFEIAVLCVVYAASIFLAVYAPDEGNRDFGGSYNSAKYKA 1629
Query: 166 VESTEVIFTGIYTFESAVKVMARGFILQPF-TYLRDAWNWLDFVVIALAYVTMG---IDL 221
+ + IF+ I+ E +K ++ G +L Y WN DF ++ ++ V+ G I L
Sbjct: 1630 LHILDDIFSIIFAVEMLLKWISMGVVLPVGRAYFWHRWNIFDFFIVIISLVSWGKPDIFL 1689
Query: 222 GNLAALRTFRVLRALKTVAI-VPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
L +R FR+L L+ + + + +S+ L +V +L + + V+A++ + +
Sbjct: 1690 RYLKVMRCFRILGPLRYWKWGSSSMSHVARTIWDSIPTLANVCLLMLMNYIVWAIIFVSL 1749
Query: 281 YM 282
+M
Sbjct: 1750 FM 1751
Score = 40.7 bits (91), Expect = 0.40
Identities = 27/104 (25%), Positives = 55/104 (52%), Gaps = 5/104 (4%)
Query: 813 ALDHHNMDKDMDKALKSGNYLRVFKLAKSWPT-LNLLISIMGRTMGALGNLTFVLCIIIF 871
A +H + ++ + L+ G L + LA + T L L ++ ++ L ++TFV I ++
Sbjct: 1991 ATNHVPFNVNVLRMLRVGRVLHLVHLALPFSTHLTLFHEVLKASVPGLISVTFVYMIAVY 2050
Query: 872 IFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMIVFRV 915
+FA++G+ G Y+ + D NF F+++ ++VFR+
Sbjct: 2051 VFAILGLHFLG--YIVPFSGYIDDKYN--NFGTFVNALIMVFRL 2090
Score = 36.7 bits (81), Expect = 6.4
Identities = 37/175 (21%), Positives = 70/175 (40%), Gaps = 16/175 (9%)
Query: 1522 RWRPQAIVFEIVTDKKFDMIIMLFI-GLNMLTMTLDHYQQSETFSAVLDYL---NMIFIV 1577
RW P+ IV+ ++ +M I L I + T + D++ ++ +
Sbjct: 129 RWTPRVIVYNVMHHWLMEMFIFLMILSYAIFQATWGRHTAPPGGMHKPDHIIWADVFYTC 188
Query: 1578 IFSSECLLKIFAL-----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRV 1632
+ E + ++FA + +F PW D V++ SI+ + + T R+
Sbjct: 189 LLGFEIIARLFASGGILHKRAFFRSPWRWLDTAVLVLSIMECTWWQDLWNF----TAWRL 244
Query: 1633 VRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+R K L V ++ L +L S L + +LL +F F + G+ F
Sbjct: 245 IRTIK---CLTYVPAPVRMKLLAKSLLRSTNRLIYVTILLTYFIFFFGLLGLQLF 296
Score = 36.7 bits (81), Expect = 6.4
Identities = 33/163 (20%), Positives = 63/163 (38%), Gaps = 7/163 (4%)
Query: 788 VALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPT--L 845
+ LL P F + I++ FM + N++R +L + P L
Sbjct: 940 IRLLALGPG-PFFTDILILIEATFMVTSLFQLGYSRTNTTSLFNWVRFLRLFRVIPCRPL 998
Query: 846 NLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDF 905
+ ++ + + + +F++ ++GM FG + ++D R F F
Sbjct: 999 RRVSRVLIHGFPDMVYALVLFTLYMFMWLLLGMSFFGSR-IGWIDYNTSDYTTRGTFETF 1057
Query: 906 MHSFMIV---FRVLCGEWIESMWDCMLVGDVSCIPFFLATVVI 945
H+ V F V +W+ W M V + +F+ATV +
Sbjct: 1058 SHAAYAVAQAFSVNRDQWLYLSWSGMRVRGGYTVLYFIATVCV 1100
>UniRef50_A0DR68 Cluster: Chromosome undetermined scaffold_60, whole
genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_60, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 2018
Score = 238 bits (582), Expect = 1e-60
Identities = 154/520 (29%), Positives = 266/520 (51%), Gaps = 31/520 (5%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
++I + F + +I S++ L L+ + L D T +F IE L+K +
Sbjct: 1193 RIINHKVFNLVIFFVICFSTIKLILDTY-------FDNFLIEFDIFITCVFLIEFLLKVI 1245
Query: 1273 ALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMS 1328
A GF Y N W LDF I+++S+I+ + FK +R LR LRPLR +
Sbjct: 1246 AQGFITEPNTYMRNTWNVLDFTIIIISIIDIPYT---DQNLSYFKVLRLLRTLRPLRLVK 1302
Query: 1329 RMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEI 1388
+ ++++V L+ ++ + NV ++ L+ +++F I+GV L K C ++ ++
Sbjct: 1303 ENKQLKLLVTTLLNSLSGVLNVTIIILLVFIMFGILGVSLLQDKMHYCDIISKDEFNYY- 1361
Query: 1389 IPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRE 1448
++ C W N MNFD++ + L LF ++ W + + ID+ + G P +
Sbjct: 1362 --NQQECKELGGEWSNRNMNFDNILNSILTLFILSRRDDWDKQIYWYIDASDDG--PEKN 1417
Query: 1449 TNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSL-EMFMTEDQKKYYNAMK 1507
+++ +Y ++LF GVI N+ K A S+ + ++ DQ+ + N K
Sbjct: 1418 AQLWIIIYFLTFIYTGSILLMDLFTGVIFVNY----KFADFSMKDKVLSPDQEDWINIQK 1473
Query: 1508 KMGSKKPLKAIPRPRWR-PQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSA 1566
+ + P A+ P +A++F+++++K FD I+ I N++ ++L++ + S +++
Sbjct: 1474 MIVASSPNFALYYPPLNFYRALIFKLISNKYFDGTIIFLIIFNVVVLSLNYDESSSNYNS 1533
Query: 1567 VLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLS---DIIEK 1622
+L+ LN+ F IF EC+LKI A YF WN FDF VV+ S L + L +
Sbjct: 1534 ILETLNLCFNFIFIGECILKIIAYGPKGYFRNSWNQFDFFVVLTSALDITLKLSGASNQN 1593
Query: 1623 YFVS--PTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFA 1680
F+S P L RV RV +V ++ RLVK KG++ L+ +LP LF + LL+ L+ IFA
Sbjct: 1594 SFLSSGPQLFRVFRVLRVTKLFRLVKQLKGLKKLIDTATFALPELFELILLMLLMYCIFA 1653
Query: 1681 IFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAG 1720
I + V D +DD YNFK F +++ LF+ +T G
Sbjct: 1654 ILATFLYSDVTDGSIIDDTYNFKNFHHALLALFRCTTGEG 1693
Score = 112 bits (269), Expect = 1e-22
Identities = 80/290 (27%), Positives = 139/290 (47%), Gaps = 42/290 (14%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMARG 189
I A+ I H LF + I++N IL+ + E+ E+ F +Y E+ +K++ +G
Sbjct: 85 ISYTALKISKHQLFEALTLVVIIINSILLSIQYDDQ-EALELTFLILYYVEALIKIIGKG 143
Query: 190 FILQPFTYLRDAWNWLDFVVIALAYVTMGIDLG-NLAALRTFRVLRALKTVAIVPGLKTI 248
I YLRD WN +D +VI + + L+ALR+ RVLR +K ++ + LK I
Sbjct: 144 LIFNSGAYLRDIWNVIDALVIVAGSLQYFMSTSVQLSALRSLRVLRPIKAISSIKSLKQI 203
Query: 249 VGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWE 308
+ S L + +++ F+ +FA++GLQ++ G +C F E +G + E +
Sbjct: 204 MTTFFLSFNELANALLVLGFTQVIFAIIGLQLFQGYTKYRC---FDE---YGIQSMEIDQ 257
Query: 309 RFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAF 368
++C N C GY+C + NP GY SFD FG A L F
Sbjct: 258 QYCHN----------------------CLDGYICGKML-ENPKKGYLSFDNFGLALLQVF 294
Query: 369 RLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
+ + W ++ L+F+ I + +++L++L LAI+ +++
Sbjct: 295 IISNLEGWVDIMAAIIYTFSEVAVLYFITFIIISAYFLIHLTLAILKVNF 344
Score = 89.0 bits (211), Expect = 1e-15
Identities = 50/171 (29%), Positives = 90/171 (52%), Gaps = 10/171 (5%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEM 1267
R FKLI N YF+ +I +I+ + + L+L + IL ++ F IF E
Sbjct: 1493 RALIFKLISNKYFDGTIIFLIIFNVVVLSLN--YDESSSNYNSILETLNLCFNFIFIGEC 1550
Query: 1268 LIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGA--------GGIQAFKTMRTLR 1319
++K +A G + YF N+W DF +V+ S ++ L GA G Q F+ R LR
Sbjct: 1551 ILKIIAYGPKGYFRNSWNQFDFFVVLTSALDITLKLSGASNQNSFLSSGPQLFRVFRVLR 1610
Query: 1320 ALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
+ R + +++G++ +++ A+P +F ++L+ L+ + IFAI+ L++
Sbjct: 1611 VTKLFRLVKQLKGLKKLIDTATFALPELFELILLMLLMYCIFAILATFLYS 1661
Score = 83.4 bits (197), Expect = 6e-14
Identities = 46/166 (27%), Positives = 90/166 (54%), Gaps = 5/166 (3%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT--TPTVESTEVIFTGIY 177
+L + D N R + I+ H +F+L I I + I +I+ T + ++ T ++
Sbjct: 1177 SLMLFDEQNAFRIICQRIINHKVFNLVIFFVICFSTIKLILDTYFDNFLIEFDIFITCVF 1236
Query: 178 TFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALK 237
E +KV+A+GFI +P TY+R+ WN LDF +I ++ + + NL+ + R+LR L+
Sbjct: 1237 LIEFLLKVIAQGFITEPNTYMRNTWNVLDFTIIIISIIDIPYTDQNLSYFKVLRLLRTLR 1296
Query: 238 TVAIV---PGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
+ +V LK +V ++ S+ + +V I+ + +F ++G+ +
Sbjct: 1297 PLRLVKENKQLKLLVTTLLNSLSGVLNVTIIILLVFIMFGILGVSL 1342
Score = 78.2 bits (184), Expect = 2e-12
Identities = 57/189 (30%), Positives = 101/189 (53%), Gaps = 13/189 (6%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR 1591
I+ F+ II LF+ N + + LD +++ L+ LN+ F ++F+ E +LKIF
Sbjct: 878 ILGTNAFEYIINLFVLANTVVLGLDGLVSNKS---ELEKLNLFFTILFTVEQVLKIFTYG 934
Query: 1592 YH-YFVEPWNLFDFVVVMFSILSLV-LSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
Y + N+FD +V+ S++ L+ LS + + LR+ R ++ RV +LV+
Sbjct: 935 ISKYSKDIMNIFDLCIVLLSLIDLLFLSSGSGSHLQAFRSLRLFRAFRIFRVTKLVRSLA 994
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVY---NFKTFV 1706
L+ L+ + +L I LLFL ++IF + GMSFF +G L + +F TF+
Sbjct: 995 YTNFLIQILSNAFYSLMYITFLLFLFIYIFTLLGMSFF-----QGALTNTQYRTSFDTFL 1049
Query: 1707 QSMILLFQM 1715
S++++ Q+
Sbjct: 1050 DSLLVVSQI 1058
Score = 77.8 bits (183), Expect = 3e-12
Identities = 60/237 (25%), Positives = 119/237 (50%), Gaps = 24/237 (10%)
Query: 1206 TLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFI 1265
T+ K+ ++ FE + +I+++S+ L+++ + ILYY++ + I
Sbjct: 84 TISYTALKISKHQLFEALTLVVIIINSILLSIQYDDQEALELTFLILYYVEAL------I 137
Query: 1266 EMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLR 1325
+++ K L Y + W +D ++++ + + + +Q +R+LR LRP++
Sbjct: 138 KIIGKGLIFNSGAYLRDIWNVIDALVIVAGSLQYFMST----SVQ-LSALRSLRVLRPIK 192
Query: 1326 AMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG-KYFKCVDMNHTTL 1384
A+S ++ ++ ++ + + N LLV +IFAI+G+QLF G ++C D +
Sbjct: 193 AISSIKSLKQIMTTFFLSFNELANALLVLGFTQVIFAIIGLQLFQGYTKYRCFD-EYGIQ 251
Query: 1385 SHEIIPDKNAC--TLENY----TWENSP---MNFDHVGKAYLCLFQVATFKGWIQIM 1432
S EI D+ C L+ Y EN ++FD+ G A L +F ++ +GW+ IM
Sbjct: 252 SMEI--DQQYCHNCLDGYICGKMLENPKKGYLSFDNFGLALLQVFIISNLEGWVDIM 306
Score = 75.8 bits (178), Expect = 1e-11
Identities = 77/331 (23%), Positives = 144/331 (43%), Gaps = 43/331 (12%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR 1591
I+ K F+++I I + + + LD Y F L ++ +F E LLK+ A
Sbjct: 1194 IINHKVFNLVIFFVICFSTIKLILDTY-----FDNFLIEFDIFITCVFLIEFLLKVIAQG 1248
Query: 1592 Y-----HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVK 1646
+ Y WN+ DF +++ SI+ + +D YF +V+R+ + R LRLVK
Sbjct: 1249 FITEPNTYMRNTWNVLDFTIIIISIIDIPYTDQNLSYF------KVLRLLRTLRPLRLVK 1302
Query: 1647 GAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF---MHVKDKGGLDDVYNFK 1703
K ++ L+ L SL + N+ +++ LV +F I G+S MH D D+ +N+
Sbjct: 1303 ENKQLKLLVTTLLNSLSGVLNVTIIILLVFIMFGILGVSLLQDKMHYCDIISKDE-FNYY 1361
Query: 1704 TFVQSMILLFQMST-SAGWDGVLDGIIN------EEECDLP-----DNERGSPGNCGSAT 1751
+ L + S + +D +L+ I+ ++ D D P
Sbjct: 1362 NQQECKELGGEWSNRNMNFDNILNSILTLFILSRRDDWDKQIYWYIDASDDGPEKNAQLW 1421
Query: 1752 IGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGS 1811
I I Y L+++ +++++++ VI NY A +++ + D + + I +
Sbjct: 1422 I-IIYFLTFIYTGSILLMDLFTGVIFVNYKFADFSMKDKVLSPDQEDWINIQKMIVASSP 1480
Query: 1812 QYIRYDQLSDFLDVLEPPLQIHKPNKYKIIS 1842
+ Y PPL ++ +K+IS
Sbjct: 1481 NFALY----------YPPLNFYRALIFKLIS 1501
Score = 62.5 bits (145), Expect = 1e-07
Identities = 40/169 (23%), Positives = 84/169 (49%), Gaps = 9/169 (5%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+R + ++ FE + +L +++ L L+ + + ++ L+ + + FT++F +E
Sbjct: 871 VRFRMNIILGTNAFEYIINLFVLANTVVLGLDGL-VSNKSELEKLNLF----FTILFTVE 925
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGG-IQAFKTMRTLRALRPLR 1325
++K G KY + D IV++SLI+ + G+G +QAF+++R RA R R
Sbjct: 926 QVLKIFTYGISKYSKDIMNIFDLCIVLLSLIDLLFLSSGSGSHLQAFRSLRLFRAFRIFR 985
Query: 1326 AMSRMQGM---RVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
++ + ++ L A S+ + + +F IF ++G+ F G
Sbjct: 986 VTKLVRSLAYTNFLIQILSNAFYSLMYITFLLFLFIYIFTLLGMSFFQG 1034
Score = 49.6 bits (113), Expect = 9e-04
Identities = 36/140 (25%), Positives = 71/140 (50%), Gaps = 13/140 (9%)
Query: 798 ELFITLCIVVNTLFMAL---DHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGR 854
+L I L +++ LF++ H + + + ++ RV KL +S N LI I+
Sbjct: 947 DLCIVLLSLIDLLFLSSGSGSHLQAFRSL-RLFRAFRIFRVTKLVRSLAYTNFLIQILSN 1005
Query: 855 TMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMIVFR 914
+L +TF+L + I+IF ++GM F + R +F F+ S ++V +
Sbjct: 1006 AFYSLMYITFLLFLFIYIFTLLGMSFFQGALTN--------TQYRTSFDTFLDSLLVVSQ 1057
Query: 915 VLCGEWIESMWDCMLVGDVS 934
+L +WI+ +++ +L+ DV+
Sbjct: 1058 ILILQWIDVLYE-LLLSDVN 1076
Score = 48.8 bits (111), Expect = 0.001
Identities = 44/190 (23%), Positives = 83/190 (43%), Gaps = 25/190 (13%)
Query: 116 SATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPT-------VES 168
S+ N P N R + ++ + F II I+ N +++ + + +E+
Sbjct: 1478 SSPNFALYYPPLNFYRALIFKLISNKYFDGTIIFLIIFNVVVLSLNYDESSSNYNSILET 1537
Query: 169 TEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLA--- 225
+ F I+ E +K++A G P Y R++WN DF V+ + + + + L +
Sbjct: 1538 LNLCFNFIFIGECILKIIAYG----PKGYFRNSWNQFDFFVVLTSALDITLKLSGASNQN 1593
Query: 226 --------ALRTFRVLRALKTVAIVP---GLKTIVGAVIESVKNLRDVIILTMFSLSVFA 274
R FRVLR K +V GLK ++ ++ L ++I+L + +FA
Sbjct: 1594 SFLSSGPQLFRVFRVLRVTKLFRLVKQLKGLKKLIDTATFALPELFELILLMLLMYCIFA 1653
Query: 275 LMGLQIYMGV 284
++ +Y V
Sbjct: 1654 ILATFLYSDV 1663
Score = 44.8 bits (101), Expect = 0.024
Identities = 32/155 (20%), Positives = 66/155 (42%), Gaps = 14/155 (9%)
Query: 142 LFSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDA 201
+ +LF++ +V + ++ +E + FT ++T E +K+ G Y +D
Sbjct: 887 IINLFVLANTVVLGLDGLVSNKSELEKLNLFFTILFTVEQVLKIFTYGI----SKYSKDI 942
Query: 202 WNWLDFVVIALAYVTM-------GIDLGNLAALRTFRVLRALKTVAIVPGL---KTIVGA 251
N D ++ L+ + + G L +LR FR R + +V L ++
Sbjct: 943 MNIFDLCIVLLSLIDLLFLSSGSGSHLQAFRSLRLFRAFRIFRVTKLVRSLAYTNFLIQI 1002
Query: 252 VIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLT 286
+ + +L + L + +F L+G+ + G LT
Sbjct: 1003 LSNAFYSLMYITFLLFLFIYIFTLLGMSFFQGALT 1037
>UniRef50_A4S9Q8 Cluster: VIC family transporter: calcium ion channel;
n=2; Ostreococcus|Rep: VIC family transporter: calcium
ion channel - Ostreococcus lucimarinus CCE9901
Length = 1742
Score = 237 bits (580), Expect = 2e-60
Identities = 174/602 (28%), Positives = 295/602 (49%), Gaps = 38/602 (6%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYY-MDRIFTVIFFIEMLIKW 1271
K++ + FE A++ MI+ S+ LA E P +Y +D FT +F EM++K
Sbjct: 874 KIVSHNLFENAILCMIIAGSVLLATETKTWPVAGSHTAKVYTAVDITFTTLFGAEMVLKL 933
Query: 1272 LALGFQK----YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAM 1327
A G + Y N++ LD ++V S+I+ AA G+G ++A +R LR +RPLR++
Sbjct: 934 FAYGLYERPTAYLKNSFNILDGVVVFTSIISLTAADDGSGSVRA---LRLLRIMRPLRSI 990
Query: 1328 SRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHE 1387
R G+R+VVN ++ AIP++ V + L+ IFA++G++LF GK++ C +N +
Sbjct: 991 RRFPGLRLVVNTVLSAIPAVSYVCFIGLVSMSIFALLGMELFMGKFWSCRVVNDAS---- 1046
Query: 1388 IIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIR 1447
+ C W N+ NFD+ G A L F + W +IM A+D+ VG
Sbjct: 1047 SYTTQATCEAAGGKWRNAKFNFDNFGAALLSTFLLHAGDDWQEIMWVAMDTTGVGTGLKT 1106
Query: 1448 ETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMK 1507
+ N LY LNL + ++DNFN K A F+T Q+++ A+
Sbjct: 1107 DNNQAAALYFVLTVAIGNFFWLNLLVTALVDNFN---KMASQDKLTFVTPAQRRWQQAIL 1163
Query: 1508 K---MGSKKPLKAIPRP---RW-RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQ 1560
+ S+ + +P P W R + + I KKF I++ + N++ +
Sbjct: 1164 RASTQDSEAWRRIVPPPGKSLWSRARLLAHHISKPKKFAYFILVVVCANLIELLTQTANM 1223
Query: 1561 SETFSAVLDYLNMIFIVIFSSECLLKIFAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDI 1619
S + +++ F ++S E +L + A R YF WN D VV+ SI+
Sbjct: 1224 SSSAEYAHFCMSIAFTAVYSLEMMLLLMAQGRTRYFRNYWNWLDAFVVVVSIV-----QA 1278
Query: 1620 IEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIF 1679
I + + ++ +++ ++ R+L+LVK G+R+L MSLP + N+ L L +F +
Sbjct: 1279 IGQSLNAGGVMNYLQLVRLLRLLKLVKAHSGLRSLFNTFIMSLPGVGNVAALSSLAIFSY 1338
Query: 1680 AIFGMSFFMHVKD--KGGLDDVY-NFKTFVQSMILLFQMSTSAGWDGVLDGIINEEEC-- 1734
AI G+S F +GG+ Y NF+ F + L + T GW G + E C
Sbjct: 1339 AIMGVSLFGDETGPFEGGVLSKYSNFQRFTTACSSLIGVYT-GGWVGTFGEVYQTEACLR 1397
Query: 1735 -DLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTD 1793
+ P S +C + Y +S+++IS ++ N+++A+ILE +S + +D EGL D
Sbjct: 1398 TEAPFMLESSI-DCSYNAAAVPYFISFVIISIFLLGNLFVAIILERFSVSADD--EGLYD 1454
Query: 1794 DD 1795
+
Sbjct: 1455 TE 1456
Score = 78.2 bits (184), Expect = 2e-12
Identities = 45/160 (28%), Positives = 88/160 (55%), Gaps = 13/160 (8%)
Query: 137 ILVHPLFSLFIITTILVNCILMIMPTT--PTVES--------TEVIFTGIYTFESAVKVM 186
I+ H LF I+ I+ +L+ T P S ++ FT ++ E +K+
Sbjct: 875 IVSHNLFENAILCMIIAGSVLLATETKTWPVAGSHTAKVYTAVDITFTTLFGAEMVLKLF 934
Query: 187 ARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI---DLGNLAALRTFRVLRALKTVAIVP 243
A G +P YL++++N LD VV+ + +++ G++ ALR R++R L+++ P
Sbjct: 935 AYGLYERPTAYLKNSFNILDGVVVFTSIISLTAADDGSGSVRALRLLRIMRPLRSIRRFP 994
Query: 244 GLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
GL+ +V V+ ++ + V + + S+S+FAL+G++++MG
Sbjct: 995 GLRLVVNTVLSAIPAVSYVCFIGLVSMSIFALLGMELFMG 1034
Score = 71.3 bits (167), Expect = 2e-10
Identities = 45/190 (23%), Positives = 92/190 (48%), Gaps = 9/190 (4%)
Query: 1530 FEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFA 1589
++I D++FD I + I N + M H+ S F + L +F+ F+ E +K
Sbjct: 357 WKIAEDRRFDASITVVIIFNTILMMSQHHAASSGFVKASEILEYVFLGCFAVEMAIKHIG 416
Query: 1590 LRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGA 1648
+ Y+ N+ D ++V ++S ++ VS + +R++R+ + R R+++
Sbjct: 417 YGFRGYWSSKQNVVDGLIVFTGVISTAVTS----QGVSASFIRLLRIGRALRTFRVIRNN 472
Query: 1649 KGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDV-YNFKTFVQ 1707
+ R ++ + + ++ ++ L IFAI+G F + G LDD F+ F++
Sbjct: 473 REFRKIISSAYLGFQDMWPFLIVWLLFQVIFAIYGFQLFTGL---GALDDERLTFRNFLR 529
Query: 1708 SMILLFQMST 1717
S + LF ++T
Sbjct: 530 SALTLFVVAT 539
Score = 66.5 bits (155), Expect = 7e-09
Identities = 59/258 (22%), Positives = 105/258 (40%), Gaps = 28/258 (10%)
Query: 172 IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFR 231
+ G++ E+ VK +A GF L YL W+ DF ++ L+ + M I + +R R
Sbjct: 32 VVAGVFAAEALVKSVALGFALGEGAYLTTNWHRFDFTLVVLSLMLMPIGGSQVVTVRLLR 91
Query: 232 VLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVK 291
L A K A + + + ++ L DV++ ++ L FA+ G+ ++ G +T +
Sbjct: 92 SLYAFKLFAKYRSARLAMKTIARALPLLGDVLLFLLWFLIFFAVSGVTMFGGRMTGRWYG 151
Query: 292 VFPEDGSWGNLTDE--NWERFCQNETN-W-----YGEGGDYP-----LCGNSS-GAGQCE 337
P+ + + C N W G G YP C +
Sbjct: 152 TPPDQATNASYVFPVGTGSETCANLVGAWMGALALGAEGTYPNEYDSTCNYKEWNTNRSA 211
Query: 338 PGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ------------LFFV 385
+ C G P G+ SF G + + A MT D W L L+F+
Sbjct: 212 TEWCCDSGI--EPYDGFLSFANAGRSSIVALNGMTIDGWNELLNPTAYAVGYPAAFLWFI 269
Query: 386 VIIFLGSFYLVNLILAIV 403
V++ +G F+++ L +++
Sbjct: 270 VVVLMGGFFMMELFTSVI 287
Score = 65.7 bits (153), Expect = 1e-08
Identities = 47/162 (29%), Positives = 80/162 (49%), Gaps = 15/162 (9%)
Query: 131 RRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTE-------VIFTGIYTFESAV 183
R +A +I F+ FI+ + N I ++ T S E + FT +Y+ E +
Sbjct: 1189 RLLAHHISKPKKFAYFILVVVCANLIELLTQTANMSSSAEYAHFCMSIAFTAVYSLEMML 1248
Query: 184 KVMARGFILQPFTYLRDAWNWLD-FVVIALAYVTMGIDL---GNLAALRTFRVLRALKTV 239
+MA+G Y R+ WNWLD FVV+ +G L G + L+ R+LR LK V
Sbjct: 1249 LLMAQGRT----RYFRNYWNWLDAFVVVVSIVQAIGQSLNAGGVMNYLQLVRLLRLLKLV 1304
Query: 240 AIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
GL+++ I S+ + +V L+ ++ +A+MG+ ++
Sbjct: 1305 KAHSGLRSLFNTFIMSLPGVGNVAALSSLAIFSYAIMGVSLF 1346
Score = 65.3 bits (152), Expect = 2e-08
Identities = 46/166 (27%), Positives = 83/166 (50%), Gaps = 7/166 (4%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQ--DILYYMDRIFTVIFFI 1265
R +K+ E+ F+ A IT++++ + L + H ++ +IL Y +F F +
Sbjct: 353 RQMCWKIAEDRRFD-ASITVVIIFNTILMMSQHHAASSGFVKASEILEY---VFLGCFAV 408
Query: 1266 EMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLR 1325
EM IK + GF+ Y+++ +D +IV +I+ G + +R RALR R
Sbjct: 409 EMAIKHIGYGFRGYWSSKQNVVDGLIVFTGVISTAVTSQGVSA-SFIRLLRIGRALRTFR 467
Query: 1326 AMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
+ + R ++++ ++ L+V L+F +IFAI G QLF G
Sbjct: 468 VIRNNREFRKIISSAYLGFQDMWPFLIVWLLFQVIFAIYGFQLFTG 513
Score = 63.3 bits (147), Expect = 6e-08
Identities = 39/115 (33%), Positives = 63/115 (54%), Gaps = 10/115 (8%)
Query: 1262 IFFIEMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRT 1317
+F E L+K +ALGF Y T W DF +V++SL+ L GG Q T+R
Sbjct: 36 VFAAEALVKSVALGFALGEGAYLTTNWHRFDFTLVVLSLM-----LMPIGGSQVV-TVRL 89
Query: 1318 LRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGK 1372
LR+L + ++ + R+ + + +A+P + +VLL L F + FA+ GV +F G+
Sbjct: 90 LRSLYAFKLFAKYRSARLAMKTIARALPLLGDVLLFLLWFLIFFAVSGVTMFGGR 144
Score = 43.2 bits (97), Expect = 0.074
Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 14/121 (11%)
Query: 1572 NMIFIVIFSSECLLKIFALRYH-----YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVS 1626
N + +F++E L+K AL + Y W+ FDF +V +LSL+L I V+
Sbjct: 30 NYVVAGVFAAEALVKSVALGFALGEGAYLTTNWHRFDFTLV---VLSLMLMPIGGSQVVT 86
Query: 1627 PTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSF 1686
LLR + K L + R + +A +LP L ++ L L + FA+ G++
Sbjct: 87 VRLLRSLYAFK------LFAKYRSARLAMKTIARALPLLGDVLLFLLWFLIFFAVSGVTM 140
Query: 1687 F 1687
F
Sbjct: 141 F 141
Score = 41.5 bits (93), Expect = 0.23
Identities = 27/90 (30%), Positives = 44/90 (48%), Gaps = 5/90 (5%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LR+ KL K+ L L + ++ +GN+ + + IF +A+MG+ LFG D F
Sbjct: 1298 LRLLKLVKAHSGLRSLFNTFIMSLPGVGNVAALSSLAIFSYAIMGVSLFG----DETGPF 1353
Query: 893 PDGDLPRW-NFTDFMHSFMIVFRVLCGEWI 921
G L ++ NF F + + V G W+
Sbjct: 1354 EGGVLSKYSNFQRFTTACSSLIGVYTGGWV 1383
Score = 39.5 bits (88), Expect = 0.91
Identities = 33/154 (21%), Positives = 73/154 (47%), Gaps = 16/154 (10%)
Query: 143 FSLFIITTILVNCILMIMP----TTPTVESTEV---IFTGIYTFESAVKVMARGFILQPF 195
F I I+ N ILM+ ++ V+++E+ +F G + E A+K + GF
Sbjct: 365 FDASITVVIIFNTILMMSQHHAASSGFVKASEILEYVFLGCFAVEMAIKHIGYGFR---- 420
Query: 196 TYLRDAWNWLDFVVIALAYVTMGIDLGNLAA--LRTFRVLRALKTVAIVPG---LKTIVG 250
Y N +D +++ ++ + ++A +R R+ RAL+T ++ + I+
Sbjct: 421 GYWSSKQNVVDGLIVFTGVISTAVTSQGVSASFIRLLRIGRALRTFRVIRNNREFRKIIS 480
Query: 251 AVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
+ +++ +I+ + +FA+ G Q++ G+
Sbjct: 481 SAYLGFQDMWPFLIVWLLFQVIFAIYGFQLFTGL 514
>UniRef50_Q01FC6 Cluster: CAC1H_MOUSE Voltage-dependent T-type calcium
channel alpha-1H subunit; n=2; Ostreococcus|Rep:
CAC1H_MOUSE Voltage-dependent T-type calcium channel
alpha-1H subunit - Ostreococcus tauri
Length = 1790
Score = 235 bits (576), Expect = 7e-60
Identities = 159/588 (27%), Positives = 296/588 (50%), Gaps = 36/588 (6%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYY-MDRIFTVIFFIE 1266
RLK +L + +F+ ++ +I++SS LA E P +Y +D +F F +E
Sbjct: 913 RLKVLRLTKQPWFDGVILLLIIVSSALLATETHTFPEEGSQTAHVYESLDIMFNACFTVE 972
Query: 1267 MLIKWLALGFQK----YFTNAWCWLDFIIVMVS-LINFVAALCGAGGIQAFKTMRTLRAL 1321
M +K ALG YF +++ +D ++V S LI F+ G +++RT+R L
Sbjct: 973 MCLKLYALGAWSAHGAYFRSSFNCMDALVVASSWLIIFL------GTAVPIRSLRTVRIL 1026
Query: 1322 RPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNH 1381
RPLR+++R++G+++VV ++ ++P++ +V ++ L I +++G++LF GK +C
Sbjct: 1027 RPLRSVNRIKGLKLVVETIMSSVPAVGSVCVIGLALMTILSVLGMELFLGKMHRC----- 1081
Query: 1382 TTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREV 1441
TL+ + K C W + NFD +A L +F +T W IM +++D V
Sbjct: 1082 -TLTSAPVATKAECLAAGGVWRKAEFNFDSFLEALLSVFIASTGDNWQDIMFESMDVVGV 1140
Query: 1442 GRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKK 1501
+P+RE + + +Y NLFI ++DNFN ++ + MT++Q+
Sbjct: 1141 DMEPVRENSKWAAVYFVVVILFAFLLWSNLFISALVDNFNRLSARSKNAKSPLMTDEQRV 1200
Query: 1502 YYNAMK---KMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHY 1558
++ AM + + P+ W+ ++ IV+ FD + ++ I NM+ M +
Sbjct: 1201 WHQAMALSITHVDNEWRRKPPQTAWK--QVIHNIVSRHSFDTVCVIMILSNMVLMMMVRE 1258
Query: 1559 QQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSLVLS 1617
S+ ++ + + E L I A+++ +Y+ WN DF+V + + LV+
Sbjct: 1259 GASKPEEDFQLWMGNALSIWYIIEAALLIIAMKWRNYWKSGWNKMDFIVAVSGTIGLVVP 1318
Query: 1618 DIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMF 1677
+ + + R++R R+ ++V+ +KG+RTL ++P + N+ +L L M+
Sbjct: 1319 AVYKSGIGG--MFRMLRFL---RLFKVVQVSKGLRTLSATFIGAVPGVINVAMLSMLFMY 1373
Query: 1678 IFAIFGMSFFMHVK---DKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEEC 1734
I++ G+SFF ++ + L + NFKTF ++MI L+ T W G L + + C
Sbjct: 1374 IYSCLGVSFFGDMRADYEGAALSEYSNFKTFPKAMISLYVCFT-GNWQGYLSDVYVDTLC 1432
Query: 1735 DLPDNERGSPG-NCGSATIGITYLLSYLVISFLIVINMYIAVILENYS 1781
NE G C I I Y +S+++I L + N+++A+ILE +S
Sbjct: 1433 --YGNEPLPNGVKCEPNYIAIVYFISFVIICVLFLGNLFVAIILERFS 1478
Score = 107 bits (256), Expect = 4e-21
Identities = 133/554 (24%), Positives = 232/554 (41%), Gaps = 49/554 (8%)
Query: 1195 DDDSPFWQGWGTL-RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHR-------- 1245
D+ S G G+L R +L+E++ F+ ++ ++ +++ LA+E LP R
Sbjct: 64 DERSLLCFGEGSLARRGCARLVEHSLFQAFILAVVAFNAVVLAME---LPDRAYEARGGS 120
Query: 1246 -PILQDILYYMDRIFTVIFFIEMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFV 1300
P+ + + + F ++F E L K +A GF Y + DFI+V V +I+
Sbjct: 121 TPLTEGGSFAVHVGFVLVFGFEALAKIIAHGFVIGPGTYLRDRSNIFDFIVVAVGVIDLS 180
Query: 1301 AALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLI 1360
A G+ G+ T+R LRAL+P RA+S + V A + LV +
Sbjct: 181 TA--GSSGVG---TLRILRALQPFRALSNSREY-VGSGFAANASTTEICANLVAGYSNSV 234
Query: 1361 FAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLF 1420
A + C + TL + + C + + ++FD G+ +
Sbjct: 235 QATGENPSYPSDLDMCAHKSENTLLRSVNGSQVYCCHSGTSPVDGFVSFDDFGRGMFVVL 294
Query: 1421 QVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNF 1480
Q T GW +I +R VG P + L + + I D
Sbjct: 295 QTMTIDGWNEIA--WTTARTVGVVPAFAFYASVVLLGGFFVFQLFTSVICATLSDIKDEK 352
Query: 1481 NEQKKKAG-GSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPR---W--------RPQAI 1528
E + +LE + E K+ + + + P W R + +
Sbjct: 353 AENDAEVKCTALERSVNETMASATGESVKVADWEAVSVLKSPTDYDWDETRGIFGRLKLL 412
Query: 1529 VFEIVTDKKFDMIIMLFIGLN---MLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLL 1585
+V D++F+M I L I N M+T T + + E F + +Y +F IF SE ++
Sbjct: 413 AISLVADERFEMFINLSIFCNVVAMMTRTAEANAELEAFRSNAEY---VFFSIFCSELMI 469
Query: 1586 KIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRL 1644
K AL Y+ WN D VV+ + +++S V+ + LR++R+ ++ RV R+
Sbjct: 470 KHVALGMRTYWARSWNRLDGAVVLSGCVDMIMS-AQGATGVNVSFLRIMRILRLFRVARV 528
Query: 1645 VKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDV-YNFK 1703
+ ++ R ++ A+ ++ L+ L + IFAI G F KG +D+ NF+
Sbjct: 529 FRRSESFRKMIRAIISGTQRMWVFLLVWALCLSIFAILGTQLF---SAKGNIDEERLNFR 585
Query: 1704 TFVQSMILLFQMST 1717
F S + LF +ST
Sbjct: 586 DFASSSLTLFVVST 599
Score = 67.7 bits (158), Expect = 3e-09
Identities = 32/123 (26%), Positives = 72/123 (58%), Gaps = 1/123 (0%)
Query: 162 TTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDL 221
T ES +++F +T E +K+ A G Y R ++N +D +V+A +++ + +
Sbjct: 954 TAHVYESLDIMFNACFTVEMCLKLYALGAWSAHGAYFRSSFNCMDALVVASSWLIIFLGT 1013
Query: 222 G-NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
+ +LRT R+LR L++V + GLK +V ++ SV + V ++ + +++ +++G+++
Sbjct: 1014 AVPIRSLRTVRILRPLRSVNRIKGLKLVVETIMSSVPAVGSVCVIGLALMTILSVLGMEL 1073
Query: 281 YMG 283
++G
Sbjct: 1074 FLG 1076
Score = 62.1 bits (144), Expect = 1e-07
Identities = 39/136 (28%), Positives = 67/136 (49%), Gaps = 17/136 (12%)
Query: 131 RRVAIYILVHPLFSLFIITTILVNCILMIMP-----------TTPTVE----STEVIFTG 175
RR ++ H LF FI+ + N +++ M +TP E + V F
Sbjct: 78 RRGCARLVEHSLFQAFILAVVAFNAVVLAMELPDRAYEARGGSTPLTEGGSFAVHVGFVL 137
Query: 176 IYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRA 235
++ FE+ K++A GF++ P TYLRD N DF+V+A+ + + + + T R+LRA
Sbjct: 138 VFGFEALAKIIAHGFVIGPGTYLRDRSNIFDFIVVAVGVI--DLSTAGSSGVGTLRILRA 195
Query: 236 LKTVAIVPGLKTIVGA 251
L+ + + VG+
Sbjct: 196 LQPFRALSNSREYVGS 211
Score = 50.4 bits (115), Expect = 5e-04
Identities = 38/166 (22%), Positives = 73/166 (43%), Gaps = 11/166 (6%)
Query: 127 FNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVIFTGI-YTFESAV-- 183
F ++ +AI ++ F +FI +I N + M+ T E + Y F S
Sbjct: 406 FGRLKLLAISLVADERFEMFINLSIFCNVVAMMTRTAEANAELEAFRSNAEYVFFSIFCS 465
Query: 184 KVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM--------GIDLGNLAALRTFRVLRA 235
++M + L TY +WN LD V+ V M G+++ L +R R+ R
Sbjct: 466 ELMIKHVALGMRTYWARSWNRLDGAVVLSGCVDMIMSAQGATGVNVSFLRIMRILRLFRV 525
Query: 236 LKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+ + ++ A+I + + +++ LS+FA++G Q++
Sbjct: 526 ARVFRRSESFRKMIRAIISGTQRMWVFLLVWALCLSIFAILGTQLF 571
Score = 45.6 bits (103), Expect = 0.014
Identities = 40/180 (22%), Positives = 75/180 (41%), Gaps = 14/180 (7%)
Query: 177 YTFESAVKVMARGFILQPFTYLRDAWNWLDFVVI---ALAYVTMGIDLGNLAAL-RTFRV 232
Y E+A+ ++A ++ Y + WN +DF+V + V + + + R R
Sbjct: 1279 YIIEAALLIIA----MKWRNYWKSGWNKMDFIVAVSGTIGLVVPAVYKSGIGGMFRMLRF 1334
Query: 233 LRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKV 292
LR K V + GL+T+ I +V + +V +L+M + +++ +G+ + +
Sbjct: 1335 LRLFKVVQVSKGLRTLSATFIGAVPGVINVAMLSMLFMYIYSCLGVSFFGDMRADYEGAA 1394
Query: 293 FPEDGSWGNLTDENWERFCQNETNWYGEGGDY---PLC-GNS--SGAGQCEPGYVCLQGF 346
E ++ + NW G D LC GN +CEP Y+ + F
Sbjct: 1395 LSEYSNFKTFPKAMISLYVCFTGNWQGYLSDVYVDTLCYGNEPLPNGVKCEPNYIAIVYF 1454
>UniRef50_Q4RB88 Cluster: Chromosome undetermined SCAF21986, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF21986, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 222
Score = 234 bits (573), Expect = 2e-59
Identities = 119/221 (53%), Positives = 152/221 (68%), Gaps = 11/221 (4%)
Query: 1408 NFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXX 1467
+FD+VG YL L QVATFKGW+ IM AIDSR V QPI E N+YMY+Y
Sbjct: 1 HFDNVGSGYLALLQVATFKGWMDIMYAAIDSRRVEDQPIYEDNLYMYIYFVIFIIFGSFF 60
Query: 1468 TLNLFIGVIIDNFNEQKKKAG-----------GSLEMFMTEDQKKYYNAMKKMGSKKPLK 1516
TLNLFIGVIIDNFN+QKKK G ++FMTE+QKKYYNAMKK+GSKKP K
Sbjct: 61 TLNLFIGVIIDNFNQQKKKNCYQIFCFSSLYFGGQDIFMTEEQKKYYNAMKKLGSKKPQK 120
Query: 1517 AIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFI 1576
IPRP+ + Q +VF+ VT + FD+ IM+ I LNM+TM ++ QS+ VL ++N +FI
Sbjct: 121 PIPRPQNKIQGLVFDFVTQQVFDISIMILICLNMVTMMVETDDQSKDTEDVLYWVNFVFI 180
Query: 1577 VIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLS 1617
V+F+ E LLK+FALR++YF WN+FD VVV+ SI+ L+
Sbjct: 181 VVFTGEFLLKLFALRHYYFTNGWNVFDVVVVILSIVGKYLA 221
Score = 49.2 bits (112), Expect = 0.001
Identities = 26/92 (28%), Positives = 50/92 (54%), Gaps = 3/92 (3%)
Query: 1212 FKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKW 1271
F + F+ +++ +I L+ + + +E +D+LY+++ +F V+F E L+K
Sbjct: 134 FDFVTQQVFDISIMILICLNMVTMMVETDD--QSKDTEDVLYWVNFVFIVVFTGEFLLKL 191
Query: 1272 LALGFQKYFTNAWCWLDFIIVMVSLINFVAAL 1303
AL YFTN W D ++V++S++ AL
Sbjct: 192 FALR-HYYFTNGWNVFDVVVVILSIVGKYLAL 222
>UniRef50_Q4SLL1 Cluster: Chromosome 15 SCAF14556, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 15 SCAF14556, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1809
Score = 234 bits (572), Expect = 2e-59
Identities = 140/460 (30%), Positives = 241/460 (52%), Gaps = 17/460 (3%)
Query: 1233 LALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGF----QKYFTNAWCWLD 1288
+ALA ED + +L Y D +FT +F EM+IK + G YF + W LD
Sbjct: 1114 IALAAEDPVCTNSE-RNKVLRYFDYVFTGVFTFEMIIKMIDQGLILHDGSYFRDMWNILD 1172
Query: 1289 FIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIF 1348
FI+V+ +LI F I+ K++R LR LRPL+ + R+ ++ V + +V ++ ++F
Sbjct: 1173 FIVVVGALIAFALTNNKGRDIKTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVTSLKNVF 1232
Query: 1349 NVLLVCLIFWLIFAIMGVQLFAGKYFKCVD--MNHTTLSHEIIPD--KNACTLENYTWEN 1404
N+L+V +F IFA++ VQLF GK+F C D M D ++ ++ W
Sbjct: 1233 NILIVYQLFMFIFAVIAVQLFKGKFFYCTDGSMKSEKECQGFYIDYTRDKKEVKRREWRR 1292
Query: 1405 SPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXX 1464
++D+VG A L LF ++T +GW Q++ + D E P R + M ++
Sbjct: 1293 HEFHYDNVGWALLTLFTISTGEGWPQVLQHSTDVTEEDMGPSRGNRMEMSVFYVVYFVVF 1352
Query: 1465 XXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWR 1524
+N+F+ +II F EQ K E + ++++ + + +K + +P+ R
Sbjct: 1353 PFFFVNIFVALIIITFQEQGDKM--IHECSLEKNERACIDF--AISAKPMTRYMPQNRQT 1408
Query: 1525 PQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECL 1584
Q ++ V F+ +++ I LN + + + +Y + VL +LN F V+FS EC+
Sbjct: 1409 FQYKLWHFVASPSFEYTVLVMIALNTVVLMMKYYSAPTAYDTVLKHLNTAFTVLFSLECI 1468
Query: 1585 LKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRL 1644
LKI A +YF + WN+FDF+ V+ SI +++ D+ ++ + L++ R A R+++L
Sbjct: 1469 LKIMAFGLNYFRDTWNIFDFITVLGSITEIIV-DLQSVNTINMSFLKLFRTA---RLIKL 1524
Query: 1645 VKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGM 1684
++ IR LL+ S AL +CLL+ ++ FI+AI GM
Sbjct: 1525 LRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGM 1564
Score = 122 bits (294), Expect = 1e-25
Identities = 93/316 (29%), Positives = 159/316 (50%), Gaps = 50/316 (15%)
Query: 116 SATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM----------PTTPT 165
+ +L+I N IR+ A I+ F I+ TI NC+++ + P
Sbjct: 61 TVNRSLFIFAEDNIIRKYARRIIDLTPFEYMILATITANCVVLALEQHLPGEDKTPMAKR 120
Query: 166 VESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVI-----ALAYVTMGID 220
+E TE F GI+ FE+ +K++A GF+ +YLR+ WN +DF+V+ A A M I
Sbjct: 121 LEKTEPYFIGIFCFEAGIKLVALGFVFHKGSYLRNGWNVMDFIVVLSGILATAGAHMNIP 180
Query: 221 LGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
+ +L LR RVLR LK V+ +P L+ ++ ++++++ L + +L F++ +FA++GL+
Sbjct: 181 V-DLRTLRAVRVLRPLKLVSGIPSLQIVLKSIMKAMIPLLQIGLLLFFAILMFAIIGLEF 239
Query: 281 YMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGY 340
Y G L Q C+ P ++ D NET D + G +C Y
Sbjct: 240 YSGKLHQTCL---PS----ADILD--------NET------VDSSELAFACGVRKCPEKY 278
Query: 341 VCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWEN-LYQ-----------LFFVVII 388
C + PN G T FD +A L+ F+ +T + W LY ++F+ +I
Sbjct: 279 ECRDTW-IGPNDGITQFDNILFAVLTVFQCITMEGWTAVLYNTNDALGITWNWMYFIPLI 337
Query: 389 FLGSFYLVNLILAIVA 404
+GSF+++NL+L +++
Sbjct: 338 IIGSFFVLNLVLGVLS 353
Score = 93.9 bits (223), Expect = 4e-17
Identities = 43/120 (35%), Positives = 75/120 (62%), Gaps = 6/120 (5%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM------GIDLGN 223
+ +FTG++TFE +K++ +G IL +Y RD WN LDF+V+ A + G D+
Sbjct: 1136 DYVFTGVFTFEMIIKMIDQGLILHDGSYFRDMWNILDFIVVVGALIAFALTNNKGRDIKT 1195
Query: 224 LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
+ +LR RVLR LKT+ +P LK + V+ S+KN+ +++I+ + +FA++ +Q++ G
Sbjct: 1196 IKSLRVLRVLRPLKTIKRLPKLKAVFDCVVTSLKNVFNILIVYQLFMFIFAVIAVQLFKG 1255
Score = 87.4 bits (207), Expect = 3e-15
Identities = 74/294 (25%), Positives = 139/294 (47%), Gaps = 32/294 (10%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLP--HRPILQDILYYMDRIFTVIFFIEMLIK 1270
++I+ T FE ++ I + + LALE HLP + + L + F IF E IK
Sbjct: 81 RIIDLTPFEYMILATITANCVVLALEQ-HLPGEDKTPMAKRLEKTEPYFIGIFCFEAGIK 139
Query: 1271 WLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
+ALGF Y N W +DFI+V+ ++ A +T+R +R LRPL+
Sbjct: 140 LVALGFVFHKGSYLRNGWNVMDFIVVLSGILATAGAHMNIP--VDLRTLRAVRVLRPLKL 197
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH 1386
+S + +++V+ ++++A+ + + L+ L+FAI+G++ ++GK + + L +
Sbjct: 198 VSGIPSLQIVLKSIMKAMIPLLQIGLLLFFAILMFAIIGLEFYSGKLHQTCLPSADILDN 257
Query: 1387 EIIPDKN---ACTL----ENY----TW---ENSPMNFDHVGKAYLCLFQVATFKGWIQIM 1432
E + AC + E Y TW + FD++ A L +FQ T +GW ++
Sbjct: 258 ETVDSSELAFACGVRKCPEKYECRDTWIGPNDGITQFDNILFAVLTVFQCITMEGWTAVL 317
Query: 1433 NDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
+ D+ + + ++Y LNL +GV+ F +++++
Sbjct: 318 YNTNDALGI---------TWNWMYFIPLIIIGSFFVLNLVLGVLSGEFAKERER 362
Score = 82.2 bits (194), Expect = 1e-13
Identities = 68/286 (23%), Positives = 133/286 (46%), Gaps = 16/286 (5%)
Query: 1508 KMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAV 1567
+ G + P + R + + +V F ++++ + LN + + + H+ Q +
Sbjct: 455 RSGRRGPAAYLRRKERMLRISIRRMVKTDTFYLMVLSLVALNTICVAIVHHNQPGWLTIF 514
Query: 1568 L----DYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIEK 1622
L DY +F+ +F +E LKI+ L + YF +N FD V++ SI +V
Sbjct: 515 LCGFGDYAEFVFLGLFLAEMFLKIYGLGFRLYFHSSFNCFDCGVIVGSIFEVVWGFFRPG 574
Query: 1623 YFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIF 1682
++LR +R+ R+ ++ K +R L+ +L S+ ++ ++ LLFL +FA+
Sbjct: 575 ISFGISVLRALRLL---RIFKITKYWASLRNLVVSLMSSMKSIISLLFLLFLFTVVFALL 631
Query: 1683 GMSFFMHVKDKGGLDDV--YNFKTFVQSMILLFQMSTSAGWDGVL-DGIINEEECDLPDN 1739
GM F + +D NF TF +++ +FQ+ T W+ V+ +GI + +
Sbjct: 632 GMQLF---GGRFIFEDYTPTNFDTFPAAIMTVFQILTGEDWNEVMYNGI--RSQGGVQYG 686
Query: 1740 ERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATE 1785
S G LLS + ++N+++A+ ++N + A E
Sbjct: 687 MWSSIYFIVLTLFGNCILLSLGALMTDTLLNVFLAIAVDNLANAQE 732
Score = 78.2 bits (184), Expect = 2e-12
Identities = 68/294 (23%), Positives = 132/294 (44%), Gaps = 36/294 (12%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPH--RPILQDILYYMDRIFTVIFF 1264
LR+ ++++ F V++++ L+++ +A+ + P L Y + +F +F
Sbjct: 472 LRISIRRMVKTDTFYLMVLSLVALNTICVAIVHHNQPGWLTIFLCGFGDYAEFVFLGLFL 531
Query: 1265 IEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPL 1324
EM +K LGF+ YF +++ D +++ S+ V G +R LR LR
Sbjct: 532 AEMFLKIYGLGFRLYFHSSFNCFDCGVIVGSIFEVVWGFFRPGISFGISVLRALRLLRIF 591
Query: 1325 RAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTL 1384
+ +R +V +L+ ++ SI ++L + +F ++FA++G+QLF G++
Sbjct: 592 KITKYWASLRNLVVSLMSSMKSIISLLFLLFLFTVVFALLGMQLFGGRFI---------- 641
Query: 1385 SHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQ 1444
E+YT P NFD A + +FQ+ T + W ++M + I S + G Q
Sbjct: 642 ------------FEDYT----PTNFDTFPAAIMTVFQILTGEDWNEVMYNGIRS-QGGVQ 684
Query: 1445 PIRETNIYMYLYX-------XXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSL 1491
++IY + LN+F+ + +DN ++ SL
Sbjct: 685 YGMWSSIYFIVLTLFGNCILLSLGALMTDTLLNVFLAIAVDNLANAQELTKWSL 738
Score = 68.5 bits (160), Expect = 2e-09
Identities = 41/162 (25%), Positives = 83/162 (51%), Gaps = 4/162 (2%)
Query: 1206 TLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFI 1265
T + K + + + FE V+ MI L+++ L ++ P +L +++ FTV+F +
Sbjct: 1408 TFQYKLWHFVASPSFEYTVLVMIALNTVVLMMKYYSAP--TAYDTVLKHLNTAFTVLFSL 1465
Query: 1266 EMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLR 1325
E ++K +A G YF + W DFI V+ S+ + L I ++ R R ++
Sbjct: 1466 ECILKIMAFGLN-YFRDTWNIFDFITVLGSITEIIVDLQSVNTIN-MSFLKLFRTARLIK 1523
Query: 1326 AMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQ 1367
+ + +R+++ VQ+ ++ V L+ + + I+AI+G+Q
Sbjct: 1524 LLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQ 1565
Score = 64.9 bits (151), Expect = 2e-08
Identities = 46/158 (29%), Positives = 79/158 (50%), Gaps = 13/158 (8%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAV---LDYLNMIFIVIFSSECLLKIFALRY-- 1592
F+ +I+ I N + + L+ + E + + L+ FI IF E +K+ AL +
Sbjct: 88 FEYMILATITANCVVLALEQHLPGEDKTPMAKRLEKTEPYFIGIFCFEAGIKLVALGFVF 147
Query: 1593 ---HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
Y WN+ DF+VV+ IL+ + + P LR +R +V R L+LV G
Sbjct: 148 HKGSYLRNGWNVMDFIVVLSGILATAGA-----HMNIPVDLRTLRAVRVLRPLKLVSGIP 202
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
++ +L ++ ++ L I LLLF + +FAI G+ F+
Sbjct: 203 SLQIVLKSIMKAMIPLLQIGLLLFFAILMFAIIGLEFY 240
Score = 62.9 bits (146), Expect = 9e-08
Identities = 38/102 (37%), Positives = 63/102 (61%), Gaps = 10/102 (9%)
Query: 827 LKSGNYLRVFKLAKSWPTL-NLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY 885
L++ LR+FK+ K W +L NL++S+M +M ++ +L F+L + +FA++GMQLFG +
Sbjct: 582 LRALRLLRIFKITKYWASLRNLVVSLMS-SMKSIISLLFLLFLFTVVFALLGMQLFGGRF 640
Query: 886 VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWD 926
+ + D P NF F + M VF++L GE W E M++
Sbjct: 641 I-FEDYTPT------NFDTFPAAIMTVFQILTGEDWNEVMYN 675
Score = 61.7 bits (143), Expect = 2e-07
Identities = 38/126 (30%), Positives = 69/126 (54%), Gaps = 8/126 (6%)
Query: 1567 VLDYLNMIFIVIFSSECLLKIF--ALRYH---YFVEPWNLFDFVVVMFSILSLVLSDIIE 1621
VL Y + +F +F+ E ++K+ L H YF + WN+ DF+VV+ ++++ L++
Sbjct: 1131 VLRYFDYVFTGVFTFEMIIKMIDQGLILHDGSYFRDMWNILDFIVVVGALIAFALTNNKG 1190
Query: 1622 KYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAI 1681
+ + LRV+RV R L+ +K ++ + + SL +FNI ++ L MFIFA+
Sbjct: 1191 RDIKTIKSLRVLRVL---RPLKTIKRLPKLKAVFDCVVTSLKNVFNILIVYQLFMFIFAV 1247
Query: 1682 FGMSFF 1687
+ F
Sbjct: 1248 IAVQLF 1253
Score = 58.0 bits (134), Expect = 2e-06
Identities = 41/173 (23%), Positives = 80/173 (46%), Gaps = 17/173 (9%)
Query: 136 YILVHPLFSLFIITTILVNCILMIMP--TTPTVEST-----EVIFTGIYTFESAVKVMAR 188
+ + P F ++ I +N ++++M + PT T FT +++ E +K+MA
Sbjct: 1415 HFVASPSFEYTVLVMIALNTVVLMMKYYSAPTAYDTVLKHLNTAFTVLFSLECILKIMAF 1474
Query: 189 GFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLG-----NLAALRTFRVLRALKTVAIVP 243
G Y RD WN DF+ + + + +DL N++ L+ FR R +K +
Sbjct: 1475 GL-----NYFRDTWNIFDFITVLGSITEIIVDLQSVNTINMSFLKLFRTARLIKLLRQGY 1529
Query: 244 GLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPED 296
++ ++ ++S K L V +L ++A++G+Q + + PED
Sbjct: 1530 TIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQKSNLMFKRLDAAALPED 1582
Score = 49.6 bits (113), Expect = 9e-04
Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 12/121 (9%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIA-------LAYVTMGIDLG 222
E +F G++ E +K+ GF L Y ++N D VI + GI G
Sbjct: 523 EFVFLGLFLAEMFLKIYGLGFRL----YFHSSFNCFDCGVIVGSIFEVVWGFFRPGISFG 578
Query: 223 NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYM 282
++ LR R+LR K L+ +V +++ S+K++ ++ L VFAL+G+Q++
Sbjct: 579 -ISVLRALRLLRIFKITKYWASLRNLVVSLMSSMKSIISLLFLLFLFTVVFALLGMQLFG 637
Query: 283 G 283
G
Sbjct: 638 G 638
>UniRef50_Q23ZH3 Cluster: Cation channel family protein; n=2;
Tetrahymena thermophila SB210|Rep: Cation channel family
protein - Tetrahymena thermophila SB210
Length = 3038
Score = 233 bits (571), Expect = 3e-59
Identities = 168/647 (25%), Positives = 304/647 (46%), Gaps = 51/647 (7%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPI-LQDILYYMDRIFTVIFFI 1265
+R + + +N F+ V+ +I+L+S L D ++ + D FT+ F
Sbjct: 2108 IRKTLYYVYKNPLFDKVVLLVIILTSFKLTF-DTYIGSADVGATKFSNNADLFFTIFFIC 2166
Query: 1266 EMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRAL 1321
E ++K ++LGF Y ++W LDF IV+ S+I+ + G I K +R LR L
Sbjct: 2167 ECVVKVVSLGFFLDEGSYLRDSWSQLDFFIVISSIIDLSLSQIDLGAI---KILRLLRTL 2223
Query: 1322 RPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNH 1381
RPLR +S+ + M+++V AL+Q++ I N++ V L+ WL+FAI+ + L GK F C
Sbjct: 2224 RPLRLLSQNKSMKLIVTALLQSMEGIANMIFVVLLIWLMFAILAMNLMGGKLFYCNTTGA 2283
Query: 1382 TTLSHEII---PDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDS 1438
S + P + L W+ P N D++G + + LF+++TF+GW +D
Sbjct: 2284 VLQSSYNVYQYPYEKCMKLPGAFWDRYPNNNDNIGFSMVMLFELSTFEGWPNYFWYYMDG 2343
Query: 1439 REVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTED 1498
+ G P+ + Y L+ ++NLF +I NF+ KKA + ++T++
Sbjct: 2344 SDTG--PVWNNSKYFSLFFAAFIFVGSFFSINLFTAIISFNFDIASKKAKNA---YLTDE 2398
Query: 1499 QKKYYNAMKKMGSKKPLKAIPRPR---WRPQAIVFEIVT----DKKFDMIIMLFIGLNML 1551
Q ++ + + P +P +R + ++ + +K+ ++M + ++
Sbjct: 2399 QSQWIELQRLIVRSTPDFTSMKPPSNFFRKFVNILKLFSRQFENKQLQNVVMENRNVIVM 2458
Query: 1552 TMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL-RYHYFVEPWNLFDFVVVMFS 1610
MT D QS F +L +N+ F +F +E + KI A YF + WN FDF VV S
Sbjct: 2459 AMTYDTSPQS--FDQILSNINLAFTSVFIAESICKIIAYGPQGYFYKGWNQFDFFVVCAS 2516
Query: 1611 ILSLVLS----DIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALF 1666
I+ +V++ +I P ++R++RV +V R+ +L+K +G+ L+ + P
Sbjct: 2517 IVDIVMTFLGKSVIGFLRAGPQIIRILRVLRVSRLFKLMKSFQGLMKLIQTTIFAFPKFL 2576
Query: 1667 NICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLD 1726
N LL L FIF+I F ++ ++ +NF F ++ ILLF+MST W V+
Sbjct: 2577 NATLLFVLFYFIFSILAWYLFSDLRSGWRINTFWNFSNFHRAFILLFRMSTGEDWYLVMY 2636
Query: 1727 GIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATED 1786
N GI + +++ + I++N+++ +I+ + + +
Sbjct: 2637 DTFN-----------------AKGVYGILFFVTFYTVQSYILMNLFVLIIMNEFEENYIN 2679
Query: 1787 VQEGLT--DDDYDMYYEIWQRFD-PDGSQYIRYDQLSDFLDVLEPPL 1830
L ++ D + + W D I + DF L+ PL
Sbjct: 2680 PDNPLNNFNEQEDDFKKRWVIMTIKDSGIKIHEKNIPDFYFELQEPL 2726
Score = 136 bits (330), Expect = 4e-30
Identities = 86/289 (29%), Positives = 156/289 (53%), Gaps = 38/289 (13%)
Query: 137 ILVHPLFSLFIITTILVNCILMIM--PTTPTVESTEV--IFTGIYTFESAVKVMARGFIL 192
I+ HP+F++ + I+ N I++ PTT + + E+ IYT E +K++A GFI
Sbjct: 332 IVNHPIFTIISLAVIIFNSIMLAKDDPTTNSDNNPEIDLALLIIYTVEMGLKIVAYGFIF 391
Query: 193 QPFTYLRDAWNWLDFVVIALAYVTMGIDLG--NLAALRTFRVLRALKTVAIVPGLKTIVG 250
Y+++ WN +D V+I ++ + NL+ALR+ RVLR L++++ V L +V
Sbjct: 392 SKNAYIKEGWNVIDLVIIVTGWLPYVVSQNAFNLSALRSLRVLRPLRSISKVKVLNQLVT 451
Query: 251 AVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERF 310
A+ S+ L+D I+ +F +VFA+ GLQ++ G L +C+ ++ +G DEN F
Sbjct: 452 ALFSSIPLLKDAFIILLFFFTVFAIAGLQLFTGQLKTRCIDIY-TGIKYG---DENNNLF 507
Query: 311 -CQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFR 369
C +++ C GA ++C +G +PN + +FDTFGW+ L+ +
Sbjct: 508 VCAVDSD----------CPPLKGA-----SFICAKGM-VSPNSDFYNFDTFGWSLLNVYV 551
Query: 370 LMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
+++ + W + ++F +I++LG++ LVNL + I+A+ Y
Sbjct: 552 VVSNEGWSTIMYYVMVGFNFFAFIYFFLIVYLGTWLLVNLCMGIIAVKY 600
Score = 101 bits (242), Expect = 2e-19
Identities = 74/262 (28%), Positives = 139/262 (53%), Gaps = 22/262 (8%)
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL 1590
++VT ++F+ ++MLF+ N + + LD S + SA L LN IF +IF+ + LK+ L
Sbjct: 1727 KLVTHQQFENLVMLFVLSNTIILCLDGIVPSSS-SATLTQLNYIFTIIFAVDMGLKLIGL 1785
Query: 1591 RY-HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
+ Y + N+FD ++V+ SIL L + +L R++RV +V RV RL++ +
Sbjct: 1786 GFTEYVSDKMNIFDAIIVILSILELAVLSGSSSVSAFRSL-RILRVFRVLRVTRLLRSLQ 1844
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF--MHVKDKGGLDDVYNFKTFVQ 1707
++ L+ A++ +L I LLLFL+MFI+A+ GM+ F + +N+ F+
Sbjct: 1845 FMKVLIAAISSTLEQFIYILLLLFLIMFIYALLGMNIFGGNWPTFNSNIPSRFNYDQFLN 1904
Query: 1708 SMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLI 1767
+ + + + T W+ L C L + S + YL+S + I I
Sbjct: 1905 AYMAVLDLVTLENWNDQL------TTCLLSN---------VSNYVCSAYLVSMIFIGNYI 1949
Query: 1768 VINMYIAVILENYSQATEDVQE 1789
+I++ +A++L+++ +++VQ+
Sbjct: 1950 LIDLVLAIMLDSFE--SDEVQK 1969
Score = 97.1 bits (231), Expect = 4e-18
Identities = 79/302 (26%), Positives = 139/302 (46%), Gaps = 30/302 (9%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT---------TPTVESTE 170
+L+I N IR+ Y+ +PLF ++ I++ + T T + +
Sbjct: 2098 SLYIFSKDNIIRKTLYYVYKNPLFDKVVLLVIILTSFKLTFDTYIGSADVGATKFSNNAD 2157
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMG---IDLGNLAAL 227
+ FT + E VKV++ GF L +YLRD+W+ LDF ++ + + + IDLG + L
Sbjct: 2158 LFFTIFFICECVVKVVSLGFFLDEGSYLRDSWSQLDFFIVISSIIDLSLSQIDLGAIKIL 2217
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQ 287
R R LR L+ ++ +K IV A+++S++ + ++I + + +FA++ + + G L
Sbjct: 2218 RLLRTLRPLRLLSQNKSMKLIVTALLQSMEGIANMIFVVLLIWLMFAILAMNLMGGKLFY 2277
Query: 288 KCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFG 347
C S N+ +E+ C + + YP N+ G L F
Sbjct: 2278 -CNTTGAVLQSSYNVYQYPYEK-CMKLPGAFWD--RYP--NNNDNIGFSMVMLFELSTFE 2331
Query: 348 PNPNYGYTSFDTFGWAFLSAFRLMTQDYWEN--LYQLFFVVIIFLGSFYLVNLILAIVAM 405
PNY W ++ T W N + LFF IF+GSF+ +NL AI++
Sbjct: 2332 GWPNY--------FWYYMDGSD--TGPVWNNSKYFSLFFAAFIFVGSFFSINLFTAIISF 2381
Query: 406 SY 407
++
Sbjct: 2382 NF 2383
Score = 87.8 bits (208), Expect = 3e-15
Identities = 49/169 (28%), Positives = 96/169 (56%), Gaps = 7/169 (4%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEM 1267
R + KL+ + FE V+ +L +++ L L+ + +P L ++ IFT+IF ++M
Sbjct: 1722 RRRIRKLVTHQQFENLVMLFVLSNTIILCLDGI-VPSSS--SATLTQLNYIFTIIFAVDM 1778
Query: 1268 LIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA- 1326
+K + LGF +Y ++ D IIV++S++ +A L G+ + AF+++R LR R LR
Sbjct: 1779 GLKLIGLGFTEYVSDKMNIFDAIIVILSILE-LAVLSGSSSVSAFRSLRILRVFRVLRVT 1837
Query: 1327 --MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
+ +Q M+V++ A+ + +LL+ + I+A++G+ +F G +
Sbjct: 1838 RLLRSLQFMKVLIAAISSTLEQFIYILLLLFLIMFIYALLGMNIFGGNW 1886
Score = 77.4 bits (182), Expect = 4e-12
Identities = 73/292 (25%), Positives = 135/292 (46%), Gaps = 40/292 (13%)
Query: 1212 FKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKW 1271
F ++ + F + +I+ +S+ LA +D D +D +I+ +EM +K
Sbjct: 330 FVIVNHPIFTIISLAVIIFNSIMLAKDDPTTN-----SDNNPEIDLALLIIYTVEMGLKI 384
Query: 1272 LALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAM 1327
+A GF Y W +D +I++ + +V + A + A +R+LR LRPLR++
Sbjct: 385 VAYGFIFSKNAYIKEGWNVIDLVIIVTGWLPYVVSQ-NAFNLSA---LRSLRVLRPLRSI 440
Query: 1328 SRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKCVDM------- 1379
S+++ + +V AL +IP + + ++ L F+ +FAI G+QLF G+ +C+D+
Sbjct: 441 SKVKVLNQLVTALFSSIPLLKDAFIILLFFFTVFAIAGLQLFTGQLKTRCIDIYTGIKYG 500
Query: 1380 --NHT----TLSHEIIPDKNA---CTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQ 1430
N+ + + P K A C + + NFD G + L ++ V + +GW
Sbjct: 501 DENNNLFVCAVDSDCPPLKGASFICAKGMVSPNSDFYNFDTFGWSLLNVYVVVSNEGWST 560
Query: 1431 IMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNE 1482
IM + VG N + ++Y +NL +G+I + E
Sbjct: 561 IMYYVM----VG------FNFFAFIYFFLIVYLGTWLLVNLCMGIIAVKYTE 602
Score = 63.7 bits (148), Expect = 5e-08
Identities = 38/164 (23%), Positives = 86/164 (52%), Gaps = 14/164 (8%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEV--IFTGIYTFESAVKVMA 187
IR++ + L LF+++ ++ C+ I+P++ + T++ IFT I+ + +K++
Sbjct: 1725 IRKLVTHQQFENLVMLFVLSNTIILCLDGIVPSSSSATLTQLNYIFTIIFAVDMGLKLIG 1784
Query: 188 RGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN--------LAALRTFRVLRALKTV 239
GF Y+ D N D +++ L+ + + + G+ L LR FRVLR + +
Sbjct: 1785 LGFT----EYVSDKMNIFDAIIVILSILELAVLSGSSSVSAFRSLRILRVFRVLRVTRLL 1840
Query: 240 AIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
+ +K ++ A+ +++ +++L + ++AL+G+ I+ G
Sbjct: 1841 RSLQFMKVLIAAISSTLEQFIYILLLLFLIMFIYALLGMNIFGG 1884
Score = 56.0 bits (129), Expect = 1e-05
Identities = 32/124 (25%), Positives = 67/124 (54%), Gaps = 7/124 (5%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKN 884
+ L+ LRV +L +S + +LI+ + T+ + +L +I+FI+A++GM +FG N
Sbjct: 1826 RILRVFRVLRVTRLLRSLQFMKVLIAAISSTLEQFIYILLLLFLIMFIYALLGMNIFGGN 1885
Query: 885 YVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCML--VGDVSCIPFFLA 941
+ + P R+N+ F++++M V ++ E W + + C+L V + C + ++
Sbjct: 1886 WPTFNSNIPS----RFNYDQFLNAYMAVLDLVTLENWNDQLTTCLLSNVSNYVCSAYLVS 1941
Query: 942 TVVI 945
+ I
Sbjct: 1942 MIFI 1945
Score = 49.2 bits (112), Expect = 0.001
Identities = 43/163 (26%), Positives = 73/163 (44%), Gaps = 15/163 (9%)
Query: 1530 FEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFA 1589
F IV F +I + I N + + D + + +D + ++I++ E LKI A
Sbjct: 330 FVIVNHPIFTIISLAVIIFNSIMLAKDDPTTNSDNNPEID---LALLIIYTVEMGLKIVA 386
Query: 1590 LRY-----HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRL 1644
+ Y E WN+ D V+++ L V+S + L +R +V R LR
Sbjct: 387 YGFIFSKNAYIKEGWNVIDLVIIVTGWLPYVVSQ-------NAFNLSALRSLRVLRPLRS 439
Query: 1645 VKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+ K + L+ AL S+P L + ++L +FAI G+ F
Sbjct: 440 ISKVKVLNQLVTALFSSIPLLKDAFIILLFFFTVFAIAGLQLF 482
Score = 44.8 bits (101), Expect = 0.024
Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 9/109 (8%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDY-VDRF 892
R+FKL KS+ L LI N T + + FIF+++ LF + ++ F
Sbjct: 2550 RLFKLMKSFQGLMKLIQTTIFAFPKFLNATLLFVLFYFIFSILAWYLFSDLRSGWRINTF 2609
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSCIPFFL 940
WNF++F +F+++FR+ GE W M+D V I FF+
Sbjct: 2610 -------WNFSNFHRAFILLFRMSTGEDWYLVMYDTFNAKGVYGILFFV 2651
Score = 36.3 bits (80), Expect = 8.5
Identities = 20/78 (25%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
Query: 805 IVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTF 864
IV++++ + L +D K L+ LR +L ++ L+++ + ++M + N+ F
Sbjct: 2196 IVISSI-IDLSLSQIDLGAIKILRLLRTLRPLRLLSQNKSMKLIVTALLQSMEGIANMIF 2254
Query: 865 VLCIIIFIFAVMGMQLFG 882
V+ +I +FA++ M L G
Sbjct: 2255 VVLLIWLMFAILAMNLMG 2272
>UniRef50_A2BHF3 Cluster: Novel protein similar to vertebrate calcium
channel, voltage- dependent, L type, alpha 1B subunit;
n=2; Danio rerio|Rep: Novel protein similar to vertebrate
calcium channel, voltage- dependent, L type, alpha 1B
subunit - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 2270
Score = 233 bits (569), Expect = 5e-59
Identities = 180/666 (27%), Positives = 324/666 (48%), Gaps = 82/666 (12%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
++ YFE ++ +I +SS+ALA ED + P ++L Y+D +FT +F EM+IK +
Sbjct: 1130 IVSLRYFEMCILVVIAMSSIALAAEDPVQANAP-RNNVLKYLDYVFTGVFTFEMVIKMVD 1188
Query: 1274 LGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSR 1329
LG YF + W LDFI+V +L+ F A G G K + T+++LR LR +
Sbjct: 1189 LGLILHPGSYFRDLWNILDFIVVSGALVAF--AFSGTKG----KDISTIKSLRVLRVLRP 1242
Query: 1330 MQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD----MNHTTLS 1385
++ ++ +P + +LF GK+F C D +
Sbjct: 1243 LK--------TIKRLPKL-------------------KLFKGKFFYCTDESKGLEKDCRG 1275
Query: 1386 HEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQP 1445
+ DK+ T + W+ ++D+V A+L LF V+T +GW ++ ++D+ + P
Sbjct: 1276 LFLDYDKDDVTAQPREWKKYEFHYDNVLWAFLTLFTVSTGEGWPTVLKHSVDATFEDQGP 1335
Query: 1446 IRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNA 1505
I M ++ +N+F+ +II F EQ K + +K
Sbjct: 1336 SPGYRIEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVLSECSL-----EKNERAC 1390
Query: 1506 MKKMGSKKPL-KAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETF 1564
+ + KPL + +P+ + Q +++ V F+ IM+ I LN + + + + + +
Sbjct: 1391 IDFAINAKPLTRYMPQNQQSFQYRLWKFVVSPPFEYSIMIMIALNTVVLMMKFHGAPDFY 1450
Query: 1565 SAVLDYLNMIFIVIFSSECLLKIFAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKY 1623
A+L YLN++F V+FS EC+LKI A +Y + WN+FDFV V+ SI +++++I E+
Sbjct: 1451 EAMLKYLNIVFTVLFSLECILKIIAFGPLNYLKDAWNVFDFVTVLGSITDILVTEINERQ 1510
Query: 1624 FVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFG 1683
++ + LR+ R A R+++L++ IR LL+ S F +FG
Sbjct: 1511 -LNFSFLRLFRAA---RLIKLLRQGYTIRILLWTFVQS-----------------FKVFG 1549
Query: 1684 MSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGS 1743
+ + D ++ NF+TF+Q+++LLF+ +T W ++ ++E CD G
Sbjct: 1550 N---IDLNDDTAINRHNNFRTFLQALMLLFRSATGEAWHDIMLSCLSERTCDPSSGTLGK 1606
Query: 1744 PGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIW 1803
CGS Y +S++ + +++N+++AVI++N+ T D L D + +W
Sbjct: 1607 --ECGS-DFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRD-SSILGPHHLDEFIRVW 1662
Query: 1804 QRFDPDGSQYIRYDQLSDFLDVLEPPLQIHK--PNK--YK-IISMDIPICRGDMMFCVDI 1858
+DP I Y + + L ++ PPL + K PN+ YK ++ M++PI + +
Sbjct: 1663 AEYDPAACGRISYKDMYNLLRIISPPLGLGKNCPNRVAYKRLVKMNMPIADDNSVHFTST 1722
Query: 1859 LDALTK 1864
L AL +
Sbjct: 1723 LMALIR 1728
Score = 137 bits (332), Expect = 2e-30
Identities = 96/312 (30%), Positives = 162/312 (51%), Gaps = 50/312 (16%)
Query: 116 SATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM----------PTTPT 165
+ +L+I N IR+ A I P F I+ TI+ NCI++ + P +
Sbjct: 65 TVNRSLFIFSEDNIIRKYAKKITECP-FEYMILATIIANCIVLGLEQHLPALDKTPMSKR 123
Query: 166 VESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVT-MGIDLGNL 224
++ TE F GI+ FE+ +K++A GF +YLR+ WN +DFVV+ +T +G D +L
Sbjct: 124 LDDTEPYFIGIFCFEAGIKIIALGFAFHKGSYLRNGWNVMDFVVVLTGILTIVGPDF-DL 182
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
LR RVLR LK V+ +P L+ ++ ++++++ L + +L F++ +FA++GL YMG
Sbjct: 183 RTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLDFYMGK 242
Query: 285 LTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQ 344
+ C + G DE +P CG S A CE G C +
Sbjct: 243 FHRTCFRT-----DTGEQVDE------------------FP-CGLESPAWTCENGTECRE 278
Query: 345 GFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYW-ENLYQ-----------LFFVVIIFLGS 392
+ PN+G T+FD +A L+ F+ +T + W + LY L+F+ +I +GS
Sbjct: 279 -YWIGPNFGITNFDNILFAVLTVFQCITMEGWVDILYNANDASGNTWNWLYFIPLIIIGS 337
Query: 393 FYLVNLILAIVA 404
F+++NL+L +++
Sbjct: 338 FFMLNLVLGVLS 349
Score = 96.3 bits (229), Expect = 8e-18
Identities = 82/309 (26%), Positives = 141/309 (45%), Gaps = 33/309 (10%)
Query: 1210 KTFKLIENTYFETAVITMILLSSLALALEDVHLP--HRPILQDILYYMDRIFTVIFFIEM 1267
K K I FE ++ I+ + + L LE HLP + + L + F IF E
Sbjct: 81 KYAKKITECPFEYMILATIIANCIVLGLEQ-HLPALDKTPMSKRLDDTEPYFIGIFCFEA 139
Query: 1268 LIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRP 1323
IK +ALGF Y N W +DF++V+ ++ V G +T+R +R LRP
Sbjct: 140 GIKIIALGFAFHKGSYLRNGWNVMDFVVVLTGILTIV------GPDFDLRTLRAVRVLRP 193
Query: 1324 LRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTT 1383
L+ +S + ++VV+ ++++A+ + + L+ L+FAI+G+ + GK+ + T
Sbjct: 194 LKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLDFYMGKFHRTCFRTDTG 253
Query: 1384 LSHEIIP---DKNACTLENYT-----WENSPM---NFDHVGKAYLCLFQVATFKGWIQIM 1432
+ P + A T EN T W NFD++ A L +FQ T +GW+ I+
Sbjct: 254 EQVDEFPCGLESPAWTCENGTECREYWIGPNFGITNFDNILFAVLTVFQCITMEGWVDIL 313
Query: 1433 NDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLE 1492
+A D+ N + +LY LNL +GV+ F +++++ E
Sbjct: 314 YNANDA---------SGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVEKRQE 364
Query: 1493 MFMTEDQKK 1501
Q++
Sbjct: 365 FLKLRRQQQ 373
Score = 93.1 bits (221), Expect = 7e-17
Identities = 51/146 (34%), Positives = 82/146 (56%), Gaps = 14/146 (9%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM--------PTTPTVESTE 170
++++I +P NP+RR+ YI+ F + I+ I ++ I + P ++ +
Sbjct: 1112 SSMFIFNPTNPVRRLCHYIVSLRYFEMCILVVIAMSSIALAAEDPVQANAPRNNVLKYLD 1171
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV------TMGIDLGNL 224
+FTG++TFE +K++ G IL P +Y RD WN LDF+V++ A V T G D+ +
Sbjct: 1172 YVFTGVFTFEMVIKMVDLGLILHPGSYFRDLWNILDFIVVSGALVAFAFSGTKGKDISTI 1231
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVG 250
+LR RVLR LKT+ +P LK G
Sbjct: 1232 KSLRVLRVLRPLKTIKRLPKLKLFKG 1257
Score = 90.6 bits (215), Expect = 4e-16
Identities = 57/219 (26%), Positives = 106/219 (48%), Gaps = 4/219 (1%)
Query: 1508 KMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAV 1567
K + L R R + + +V + F ++ +GLN L + + HY Q E +
Sbjct: 457 KSSKIESLSYFRRKEKRFRFFIRRMVKAQSFYWTVLCIVGLNTLCVAIVHYDQPEWLTYA 516
Query: 1568 LDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVS 1626
L +F+ +F E LK++ L YF +N FDF V++ SI ++ + +
Sbjct: 517 LYLAEFVFLGLFLIEMSLKMYGLGPRTYFHSSFNCFDFGVIVGSIFEVIWAAVKPGASFG 576
Query: 1627 PTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSF 1686
++LR +R+ R+ ++ K +R L+ +L S+ ++ ++ LLFL + +FA+ GM
Sbjct: 577 ISVLRALRLL---RIFKVTKYWNSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQL 633
Query: 1687 FMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVL 1725
F + NF TF +++ +FQ+ T W+ V+
Sbjct: 634 FGGQFNFEDETPTTNFDTFPAAILTVFQILTGEDWNAVM 672
Score = 86.6 bits (205), Expect = 6e-15
Identities = 70/305 (22%), Positives = 132/305 (43%), Gaps = 32/305 (10%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
++++ F V+ ++ L++L +A+ VH L LY + +F +F IEM +K
Sbjct: 480 RMVKAQSFYWTVLCIVGLNTLCVAI--VHYDQPEWLTYALYLAEFVFLGLFLIEMSLKMY 537
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG 1332
LG + YF +++ DF +++ S+ + A G +R LR LR +
Sbjct: 538 GLGPRTYFHSSFNCFDFGVIVGSIFEVIWAAVKPGASFGISVLRALRLLRIFKVTKYWNS 597
Query: 1333 MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDK 1392
+R +V +L+ ++ SI ++L + +F ++FA++G+QLF G++
Sbjct: 598 LRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQF------------------- 638
Query: 1393 NACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIY 1452
N+ E NFD A L +FQ+ T + W +M I+S Q ++
Sbjct: 639 ------NFEDETPTTNFDTFPAAILTVFQILTGEDWNAVMYHGIES-----QGGVHRGMF 687
Query: 1453 MYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSK 1512
+Y LN+F+ + +DN ++ E +K K++
Sbjct: 688 CSVYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEEEQEEAISKKLALQKAKEVKEV 747
Query: 1513 KPLKA 1517
P+ A
Sbjct: 748 SPMSA 752
Score = 70.9 bits (166), Expect = 3e-10
Identities = 53/164 (32%), Positives = 83/164 (50%), Gaps = 17/164 (10%)
Query: 1533 VTDKKFDMIIMLFIGLNMLTMTLDHYQQS---ETFSAVLDYLNMIFIVIFSSECLLKIFA 1589
+T+ F+ +I+ I N + + L+ + + S LD FI IF E +KI A
Sbjct: 86 ITECPFEYMILATIIANCIVLGLEQHLPALDKTPMSKRLDDTEPYFIGIFCFEAGIKIIA 145
Query: 1590 L--RYH---YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRL 1644
L +H Y WN+ DFVVV+ IL++V D LR +R +V R L+L
Sbjct: 146 LGFAFHKGSYLRNGWNVMDFVVVLTGILTIVGPDFD---------LRTLRAVRVLRPLKL 196
Query: 1645 VKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
V G ++ +L ++ ++ L I LLLF + +FAI G+ F+M
Sbjct: 197 VSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLDFYM 240
Score = 61.3 bits (142), Expect = 3e-07
Identities = 37/101 (36%), Positives = 62/101 (61%), Gaps = 9/101 (8%)
Query: 827 LKSGNYLRVFKLAKSWPTL-NLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY 885
L++ LR+FK+ K W +L NL++S++ +M ++ +L F+L + I +FA++GMQLFG +
Sbjct: 580 LRALRLLRIFKVTKYWNSLRNLVVSLLN-SMKSIISLLFLLFLFIVVFALLGMQLFGGQF 638
Query: 886 VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMW 925
F D + P NF F + + VF++L GE W M+
Sbjct: 639 -----NFED-ETPTTNFDTFPAAILTVFQILTGEDWNAVMY 673
Score = 59.3 bits (137), Expect = 1e-06
Identities = 35/149 (23%), Positives = 77/149 (51%), Gaps = 3/149 (2%)
Query: 1202 QGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTV 1261
Q + + + +K + + FE +++ MI L+++ L ++ P + +L Y++ +FTV
Sbjct: 1406 QNQQSFQYRLWKFVVSPPFEYSIMIMIALNTVVLMMKFHGAPD--FYEAMLKYLNIVFTV 1463
Query: 1262 IFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRAL 1321
+F +E ++K +A G Y +AW DF+ V+ S+ + + + F +R RA
Sbjct: 1464 LFSLECILKIIAFGPLNYLKDAWNVFDFVTVLGSITDILVTEINERQLN-FSFLRLFRAA 1522
Query: 1322 RPLRAMSRMQGMRVVVNALVQAIPSIFNV 1350
R ++ + + +R+++ VQ+ N+
Sbjct: 1523 RLIKLLRQGYTIRILLWTFVQSFKVFGNI 1551
Score = 56.0 bits (129), Expect = 1e-05
Identities = 36/121 (29%), Positives = 62/121 (51%), Gaps = 12/121 (9%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIA-------LAYVTMGIDLG 222
E +F G++ E ++K+ G P TY ++N DF VI A V G G
Sbjct: 521 EFVFLGLFLIEMSLKMYGLG----PRTYFHSSFNCFDFGVIVGSIFEVIWAAVKPGASFG 576
Query: 223 NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYM 282
++ LR R+LR K L+ +V +++ S+K++ ++ L + VFAL+G+Q++
Sbjct: 577 -ISVLRALRLLRIFKVTKYWNSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFG 635
Query: 283 G 283
G
Sbjct: 636 G 636
Score = 44.8 bits (101), Expect = 0.024
Identities = 35/133 (26%), Positives = 66/133 (49%), Gaps = 18/133 (13%)
Query: 138 LVHPLFSLFIITTILVNCILMIMPTTPTVESTE-------VIFTGIYTFESAVKVMARGF 190
+V P F I+ I +N ++++M + E ++FT +++ E +K++A G
Sbjct: 1419 VVSPPFEYSIMIMIALNTVVLMMKFHGAPDFYEAMLKYLNIVFTVLFSLECILKIIAFG- 1477
Query: 191 ILQPFTYLRDAWNWLDFVVIALAYVT--MGIDLG----NLAALRTFRVLRALKTVAIVPG 244
P YL+DAWN DFV + L +T + ++ N + LR FR R +K +
Sbjct: 1478 ---PLNYLKDAWNVFDFVTV-LGSITDILVTEINERQLNFSFLRLFRAARLIKLLRQGYT 1533
Query: 245 LKTIVGAVIESVK 257
++ ++ ++S K
Sbjct: 1534 IRILLWTFVQSFK 1546
>UniRef50_Q01AV1 Cluster: Calcium channel, voltage-dependent, T type,
alpha 1G subunit; n=3; cellular organisms|Rep: Calcium
channel, voltage-dependent, T type, alpha 1G subunit -
Ostreococcus tauri
Length = 1785
Score = 228 bits (558), Expect = 1e-57
Identities = 173/595 (29%), Positives = 286/595 (48%), Gaps = 51/595 (8%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+R F LI++ FE ++ +ILLS LA+ + L ++ D FT+IF E
Sbjct: 1189 MRRLVFMLIKHKVFERLMLFIILLSCAQLAVSAPTVNPYSDLAKVMKSADVSFTLIFAFE 1248
Query: 1267 MLIKWLALGFQK----YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALR 1322
+IK A+GF Y + LDFIIV+VS++ V+A A +Q +T R +R LR
Sbjct: 1249 AIIKIFAMGFAMHPGAYLRSYANCLDFIIVLVSIVVEVSA--NASKLQFMRTFRLVRVLR 1306
Query: 1323 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHT 1382
PLR ++RM+ M++ V LV P + N + +G + G + +D N
Sbjct: 1307 PLRLLNRMKSMQIAVATLVHISPELVN-----FDYCNDPTALGRETCVGTF---IDANGA 1358
Query: 1383 TLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVG 1442
++ + W + P+NFD+ + L LF V T GWI I +DS +
Sbjct: 1359 HITRQ--------------WLHPPLNFDNTLISILTLFVVVTRDGWIDIAFQGMDSTALD 1404
Query: 1443 RQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKY 1502
QP N + +Y ++ + ++ ++ + +G S M ++E+Q+++
Sbjct: 1405 SQPSLNKNGWSAIYFLTFMVIVSFVWTSMIVALVCHHYKSADELSGSS--MILSEEQREW 1462
Query: 1503 YNAMKKMGSKKPLKAIPR-----PRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDH 1557
+ ++ + LK + PR+ + F +VT +F+ I+ I N +TM H
Sbjct: 1463 SDILRMKKHEAELKVVDDSDAAGPRFFLRKSTFSLVTSPRFENFIIFCIIANTVTMASYH 1522
Query: 1558 YQQSETFSAVLDYLNMIFIVIFSSECLLKIFA-LRYHYFVEPWNLFDFVVVMFSILSLVL 1616
Q ++ + N+ F IF E LK+ A L YF EPWN+FDF+VV+ SI L
Sbjct: 1523 NDQPALYAELQRSANIFFSWIFLLELALKLCAFLPQRYFSEPWNVFDFIVVVASIPDLAG 1582
Query: 1617 SDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVM 1676
D FV +LRVVR+ GR+LRL K A+G+R + L S + +I L+ ++M
Sbjct: 1583 VD-----FVGTNVLRVVRL---GRILRLFKQARGLRAVFNTLVSSFEGVSHIFFLIVMLM 1634
Query: 1677 FIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDL 1736
F++A+ GM+ F V NF+ F S+++L ++ T W V+ ++ +CD
Sbjct: 1635 FVYAVLGMNIFGDYDTNYPRGRVENFRNFGSSLMVLLRVITRDNWKRVM---LDTMKCDY 1691
Query: 1737 PDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGL 1791
+E G NC + + Y +++ ++I M IA +L + A V EGL
Sbjct: 1692 --DEGGVAANCSNIFVPALYFTTFIFFGAYVLIGMIIACVLSKF--AENAVNEGL 1742
Score = 128 bits (309), Expect = 2e-27
Identities = 137/578 (23%), Positives = 238/578 (41%), Gaps = 60/578 (10%)
Query: 1184 QCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLP 1243
+ ++ P D + +R +LI +FE + I+ + +ALAL L
Sbjct: 57 ETWELLPMNESDMSLCLFPSTSAVRRNARRLIAWVWFERVTLATIIANCVALALYKP-LE 115
Query: 1244 HRPILQDILYYMDRIFTVIFFIEMLIKWLALGF-------QKYFTNAWCWLDFIIVMVSL 1296
L + +FT IF +E+ +K +A F Y + W LDF+IV+
Sbjct: 116 DEGSWNKGLDVAETVFTAIFTLELTLKVVANNFLFGPPDVDVYLRDGWRVLDFLIVVGGW 175
Query: 1297 INFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG-MRVVVNALVQAIPSIFNVLLVCL 1355
I+F + G G +R LRALRPL+++S V ++ ++ + NVL +
Sbjct: 176 ISFGLTVSGRSG-GGLTAVRGLRALRPLKSISSFSSNASVSLSTTFASMGMVLNVLFFVV 234
Query: 1356 IFWLIFAIMGVQLFAGKYF-KCV-DMNHTTLSHEI------------IPDKNACTLENYT 1401
I ++ I+GVQ FAG +C+ + ++++I C + T
Sbjct: 235 IVIIVLGILGVQRFAGTLNGRCMHESTREFVAYDIDVACSVNSGGHTCGASQICVATSLT 294
Query: 1402 -WENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXX 1460
++N FD++ A +++V T +GW+ +M ID I IY L
Sbjct: 295 GFDNGHTTFDNILGASFIIYRVLTLRGWVDLMYQVIDGTGDRTMVI----IYFLLAVMFG 350
Query: 1461 XXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKP------ 1514
L K A G EM+ +K++ S++P
Sbjct: 351 AVFISSFVLAAVATKYRQTAIVDAKMADG--EMYEQITPPMSARNVKRVASRRPGEFSYG 408
Query: 1515 ------LKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVL 1568
L R Q + ++V F+ I + I N + + + + SE +L
Sbjct: 409 ERISKDLLEFMRKDLAYQKPLRQLVEHHHFENAITVAIVANTILLAVQYRDMSEQVETIL 468
Query: 1569 DYLNMIFIVIFSSECLLKIFALRYHYFV-EPWNLFDFVVVMFSILSLVLSDIIEKYFVSP 1627
+ F+ +F E +LK+ A +V + +N+FD +V+ ++ + + S
Sbjct: 469 TSCHYAFLCLFCVELVLKVLANGILGYVRDRYNVFDATIVIAGLIEVAFGNS------SF 522
Query: 1628 TLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+ R R+ +V R RL+ K IR L+ L ++F+ C LLF+ +F+F + G F
Sbjct: 523 AVARAFRLLRVLRATRLIARNKNIRRLIDIALEGLSSIFSFCGLLFVFVFVFTVLGTQLF 582
Query: 1688 MHVKDKGGLDDVY----NFKTFVQSMILLFQMSTSAGW 1721
GG + Y NF TF S + +F++ T A W
Sbjct: 583 ------GGKPEFYNVRPNFNTFGDSFLTVFEILTGASW 614
Score = 83.0 bits (196), Expect = 7e-14
Identities = 71/318 (22%), Positives = 139/318 (43%), Gaps = 51/318 (16%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM--------PTTPTVESTEV 171
+L + + +RR A ++ F + TI+ NC+ + + ++ E
Sbjct: 70 SLCLFPSTSAVRRNARRLIAWVWFERVTLATIIANCVALALYKPLEDEGSWNKGLDVAET 129
Query: 172 IFTGIYTFESAVKVMARGFILQP---FTYLRDAWNWLDFVVIALAYVTMGIDL-----GN 223
+FT I+T E +KV+A F+ P YLRD W LDF+++ +++ G+ + G
Sbjct: 130 VFTAIFTLELTLKVVANNFLFGPPDVDVYLRDGWRVLDFLIVVGGWISFGLTVSGRSGGG 189
Query: 224 LAALRTFRVLRALKTVAIVPGLKTI-VGAVIESVKNLRDVIILTMFSLSVFALMGLQIYM 282
L A+R R LR LK+++ ++ + S+ + +V+ + + V ++G+Q +
Sbjct: 190 LTAVRGLRALRPLKSISSFSSNASVSLSTTFASMGMVLNVLFFVVIVIIVLGILGVQRFA 249
Query: 283 GVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVC 342
G L +C+ E+ F + + C +SG C +C
Sbjct: 250 GTLNGRCM-------------HESTREFVAYDID--------VACSVNSGGHTCGASQIC 288
Query: 343 LQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENL-YQ------------LFFVVIIF 389
+ + G+T+FD A +R++T W +L YQ ++F++ +
Sbjct: 289 VATSLTGFDNGHTTFDNILGASFIIYRVLTLRGWVDLMYQVIDGTGDRTMVIIYFLLAVM 348
Query: 390 LGSFYLVNLILAIVAMSY 407
G+ ++ + +LA VA Y
Sbjct: 349 FGAVFISSFVLAAVATKY 366
Score = 76.2 bits (179), Expect = 9e-12
Identities = 44/144 (30%), Positives = 81/144 (56%), Gaps = 12/144 (8%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTV----------EST 169
+L I P P+RR+ ++ H +F ++ IL++C + + + PTV +S
Sbjct: 1179 SLMIFKPRLPMRRLVFMLIKHKVFERLMLFIILLSCAQLAV-SAPTVNPYSDLAKVMKSA 1237
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVT-MGIDLGNLAALR 228
+V FT I+ FE+ +K+ A GF + P YLR N LDF+++ ++ V + + L +R
Sbjct: 1238 DVSFTLIFAFEAIIKIFAMGFAMHPGAYLRSYANCLDFIIVLVSIVVEVSANASKLQFMR 1297
Query: 229 TFRVLRALKTVAIVPGLKTIVGAV 252
TFR++R L+ + ++ +K++ AV
Sbjct: 1298 TFRLVRVLRPLRLLNRMKSMQIAV 1321
Score = 62.5 bits (145), Expect = 1e-07
Identities = 55/217 (25%), Positives = 96/217 (44%), Gaps = 21/217 (9%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIM--PTTPTV-----ESTEVIFTGIYTFESA 182
+R+ ++ P F FII I+ N + M P + S + F+ I+ E A
Sbjct: 1490 LRKSTFSLVTSPRFENFIIFCIIANTVTMASYHNDQPALYAELQRSANIFFSWIFLLELA 1549
Query: 183 VKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM-GIDLGNLAALRTFRVLRALKTVAI 241
+K+ A F+ P Y + WN DF+V+ + + G+D LR R+ R L+
Sbjct: 1550 LKLCA--FL--PQRYFSEPWNVFDFIVVVASIPDLAGVDFVGTNVLRVVRLGRILRLFKQ 1605
Query: 242 VPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLT---QKCVKVFPEDGS 298
GL+ + ++ S + + + L + + V+A++G+ I+ T + V+ F GS
Sbjct: 1606 ARGLRAVFNTLVSSFEGVSHIFFLIVMLMFVYAVLGMNIFGDYDTNYPRGRVENFRNFGS 1665
Query: 299 -----WGNLTDENWERFCQNETNW-YGEGGDYPLCGN 329
+T +NW+R + Y EGG C N
Sbjct: 1666 SLMVLLRVITRDNWKRVMLDTMKCDYDEGGVAANCSN 1702
Score = 57.2 bits (132), Expect = 4e-06
Identities = 68/283 (24%), Positives = 125/283 (44%), Gaps = 24/283 (8%)
Query: 1514 PLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLN--MLTMTLDHYQQSETFSAVLDYL 1571
P I +PR + +VF ++ K F+ +++ I L+ L ++ + V+
Sbjct: 1178 PSLMIFKPRLPMRRLVFMLIKHKVFERLMLFIILLSCAQLAVSAPTVNPYSDLAKVMKSA 1237
Query: 1572 NMIFIVIFSSECLLKIFALRY--H---YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVS 1626
++ F +IF+ E ++KIFA+ + H Y N DF++V+ SI+ V ++ + F
Sbjct: 1238 DVSFTLIFAFEAIIKIFAMGFAMHPGAYLRSYANCLDFIIVLVSIVVEVSANASKLQF-- 1295
Query: 1627 PTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPAL--FNIC--LLLFLVMFIFAIF 1682
+R R+ +V R LRL+ K ++ + L P L F+ C F
Sbjct: 1296 ---MRTFRLVRVLRPLRLLNRMKSMQIAVATLVHISPELVNFDYCNDPTALGRETCVGTF 1352
Query: 1683 GMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERG 1742
+ H+ + L NF + S++ LF + T GW +D + D++
Sbjct: 1353 IDANGAHI-TRQWLHPPLNFDNTLISILTLFVVVTRDGW---IDIAFQGMDSTALDSQPS 1408
Query: 1743 SPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATE 1785
N SA Y L+++VI + +M +A++ +Y A E
Sbjct: 1409 LNKNGWSA----IYFLTFMVIVSFVWTSMIVALVCHHYKSADE 1447
Score = 51.6 bits (118), Expect = 2e-04
Identities = 37/157 (23%), Positives = 69/157 (43%), Gaps = 14/157 (8%)
Query: 137 ILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVIFTGI-YTF------ESAVKVMARG 189
++ H F I I+ N IL+ + E E I T Y F E +KV+A G
Sbjct: 432 LVEHHHFENAITVAIVANTILLAVQYRDMSEQVETILTSCHYAFLCLFCVELVLKVLANG 491
Query: 190 FILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIV---PGLK 246
+ Y+RD +N D ++ + + + A R FR+LR L+ ++ ++
Sbjct: 492 IL----GYVRDRYNVFDATIVIAGLIEVAFGNSSFAVARAFRLLRVLRATRLIARNKNIR 547
Query: 247 TIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
++ +E + ++ L + VF ++G Q++ G
Sbjct: 548 RLIDIALEGLSSIFSFCGLLFVFVFVFTVLGTQLFGG 584
Score = 50.8 bits (116), Expect = 4e-04
Identities = 30/105 (28%), Positives = 58/105 (55%), Gaps = 10/105 (9%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKN 884
+ ++ G LR+FK A+ L + + + + + ++ F++ +++F++AV+GM +FG
Sbjct: 1592 RVVRLGRILRLFKQARG---LRAVFNTLVSSFEGVSHIFFLIVMLMFVYAVLGMNIFG-- 1646
Query: 885 YVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
DY +P G + NF +F S M++ RV+ + W M D M
Sbjct: 1647 --DYDTNYPRGRVE--NFRNFGSSLMVLLRVITRDNWKRVMLDTM 1687
Score = 38.7 bits (86), Expect = 1.6
Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 9/105 (8%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKN 884
+A + LR +L + LI I + ++ + +L + +F+F V+G QLFG
Sbjct: 526 RAFRLLRVLRATRLIARNKNIRRLIDIALEGLSSIFSFCGLLFVFVFVFTVLGTQLFGGK 585
Query: 885 YVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCG-EWIESMWDCM 928
P+ R NF F SF+ VF +L G W ++ M
Sbjct: 586 --------PEFYNVRPNFNTFGDSFLTVFEILTGASWYKTALTAM 622
>UniRef50_A0BZH2 Cluster: Chromosome undetermined scaffold_139, whole
genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_139, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 1754
Score = 228 bits (558), Expect = 1e-57
Identities = 160/646 (24%), Positives = 322/646 (49%), Gaps = 29/646 (4%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
LR K LI++ Y++ A+ + I+LS+L L D L ++ D+ Y FT IF ++
Sbjct: 823 LRKKLHILIQSKYYDWAM-SFIILSNLILLGYDQPLRKENLVIDVFNYA---FTGIFILD 878
Query: 1267 MLIKWLALGF--------QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTL 1318
IK LA GF + Y N LDF+++++S ++ + + + ++AF+ +RTL
Sbjct: 879 AFIKILAQGFYWNKQEPQKSYIMNNNNQLDFVVLIISSLDDLN-IYKSQYLRAFRALRTL 937
Query: 1319 RALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD 1378
R L LR S+ + + ++ +L+Q I + +++ V I I +I+ + ++ GK + C
Sbjct: 938 RILITLRRGSQNEQLNLISRSLLQTISLLSSMIFVTGISLWILSIICMTIWKGKLYFCSQ 997
Query: 1379 MNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDS 1438
++ + I + C + W N+ N+D + + LCLF++ +GW Q M D
Sbjct: 998 VS--LKDFQDIVNVEDCLAKGGQWINNITNYDTIQDSLLCLFRLIIGEGWTQQMFSVSDI 1055
Query: 1439 REVGRQP-IRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTE 1497
G P I ++ Y + + LNL G+II+N+ K+ ++ E
Sbjct: 1056 TNRGLNPKINSSSQYQFFFYVLIFSLNIVL-LNLITGLIINNYRTIKENIANFQQL--NE 1112
Query: 1498 DQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDH 1557
Q+++ M+ M KK + IP+P + + I + + +++ F+ +I++ + +N++ L
Sbjct: 1113 FQRQWIQMMQIMQKKKLIYLIPKPSSKYRLICYHLASNQYFETVILILLVVNLILQLLHS 1172
Query: 1558 YQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLS 1617
Y QS T L +++ FIVIF E +K+ A H+F + N FD ++++ + + L++
Sbjct: 1173 YLQSITTQEALYGMSIFFIVIFHVELFIKLLAYWVHFFRDILNKFDIIILIVTDVLLIMK 1232
Query: 1618 DIIE--KYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLV 1675
D + + + P ++R +R+ K ++ R K +R L+ + +P L ++ + + +
Sbjct: 1233 DSFDLPRLYTIPLIIRSLRIIKANKLFRF---NKQLRVLIDVIQDLIPTLLSVIVFIAIT 1289
Query: 1676 MFIFAIFGMSFFMHV--KDKGGLDDVYNFKTFVQSMILLFQMSTSAGWD-GVLDGIINEE 1732
+ I+++ G+ F V +F F+ +++L +ST W + D I+ +
Sbjct: 1290 IIIYSLIGVQTFSTVWSTSSDPHQRTKSFSNFLDGVLILIDISTGQYWSLYMADYTIDTK 1349
Query: 1733 ECDLPDNER-GSPGNCGSATI-GITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEG 1790
C E+ S G G +TI G + +S+LV+ +I+ ++++A+I+E+Y + +
Sbjct: 1350 GCHAQTPEQFESEGARGCSTIFGYFFFISFLVLIRIIMTSLFLAMIIESYQECQLENTAA 1409
Query: 1791 LTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHKPN 1836
+ + + W +DP G+ +I + + + + PPL N
Sbjct: 1410 INPYQLEDFLVKWSDYDPQGTGWITPEDFAFLMFEINPPLGFKDEN 1455
Score = 54.4 bits (125), Expect = 3e-05
Identities = 76/327 (23%), Positives = 156/327 (47%), Gaps = 34/327 (10%)
Query: 97 YHNQTTFVVISKGKDIFR-FSATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNC 155
+ + F +IS + ++ F ++L+IL + +R+ ++IL+ + + ++ I+++
Sbjct: 789 FKSSDDFQIISLYQQNWKEFFGNSSLFILHNRSNLRK-KLHILIQSKYYDWAMSFIILSN 847
Query: 156 ILMIMPTTPTVESTEVI------FTGIYTFESAVKVMARGFIL---QPF-TYLRDAWNWL 205
++++ P + VI FTGI+ ++ +K++A+GF +P +Y+ + N L
Sbjct: 848 LILLGYDQPLRKENLVIDVFNYAFTGIFILDAFIKILAQGFYWNKQEPQKSYIMNNNNQL 907
Query: 206 DFVVIALAYVT-MGID----LGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLR 260
DFVV+ ++ + + I L ALRT R+L L+ + L I ++++++ L
Sbjct: 908 DFVVLIISSLDDLNIYKSQYLRAFRALRTLRILITLRRGSQNEQLNLISRSLLQTISLLS 967
Query: 261 DVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGE 320
+I +T SL + +++ + I+ G L C +V +D D N + +
Sbjct: 968 SMIFVTGISLWILSIICMTIWKGKL-YFCSQVSLKD-----FQD------IVNVEDCLAK 1015
Query: 321 GGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLY 380
GG + N + + +CL F G+T F + ++ L + + Y
Sbjct: 1016 GGQW--INNITNYDTIQDSLLCL--FRLIIGEGWTQ-QMFSVSDITNRGLNPKINSSSQY 1070
Query: 381 QLFFVVIIFLGSFYLVNLILAIVAMSY 407
Q FF V+IF + L+NLI ++ +Y
Sbjct: 1071 QFFFYVLIFSLNIVLLNLITGLIINNY 1097
Score = 40.7 bits (91), Expect = 0.40
Identities = 34/174 (19%), Positives = 76/174 (43%), Gaps = 20/174 (11%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM-------PTTPTVESTEVIFTGIYT 178
P + R + ++ + F I+ ++VN IL ++ T + + F I+
Sbjct: 1136 PSSKYRLICYHLASNQYFETVILILLVVNLILQLLHSYLQSITTQEALYGMSIFFIVIFH 1195
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM----GIDLGNLAAL----RTF 230
E +K++A + RD N D +++ + V + DL L + R+
Sbjct: 1196 VELFIKLLAYWV-----HFFRDILNKFDIIILIVTDVLLIMKDSFDLPRLYTIPLIIRSL 1250
Query: 231 RVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
R+++A K L+ ++ + + + L VI+ ++ +++L+G+Q + V
Sbjct: 1251 RIIKANKLFRFNKQLRVLIDVIQDLIPTLLSVIVFIAITIIIYSLIGVQTFSTV 1304
Score = 37.9 bits (84), Expect = 2.8
Identities = 39/146 (26%), Positives = 68/146 (46%), Gaps = 6/146 (4%)
Query: 1248 LQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAG 1307
L+ L ++ +F VI+ IE + + + + QK + L+FI V LI V L
Sbjct: 503 LEGTLAKINVVFLVIYLIEDIAR-IYIWKQKE-SKIIVLLEFICDFVGLIVQVNQLEHPF 560
Query: 1308 GIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQ 1367
T++ +R L + RV+++AL ++ +I ++L+ I+ L+ +MG
Sbjct: 561 ---ILNTIKGIRLLWVFNYQTSWSNYRVLLSALWKSFNNIPIMILILFIYGLVIGLMGRN 617
Query: 1368 LFAGKYFKCVDMNHTTLSHEIIPDKN 1393
FAGK + D+ L IP N
Sbjct: 618 FFAGK-LRFNDLGFYDLDGSYIPRAN 642
>UniRef50_A0DXP6 Cluster: Chromosome undetermined scaffold_69, whole
genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_69, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 1713
Score = 223 bits (545), Expect = 4e-56
Identities = 163/658 (24%), Positives = 326/658 (49%), Gaps = 47/658 (7%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQ--DILYYMDRIFTVIFF 1264
LR + +L ++ YFE + ++I+L+ + L ++ PI + D++ + IFT+IF
Sbjct: 798 LRKRIQQLTQSKYFEWLMSSIIILNIILLGMD------LPIFEQKDLIQKFNLIFTIIFI 851
Query: 1265 IEMLIKWLALGF--------QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMR 1316
E++++ LA GF + + N D I+++S I+ + L +G ++AF+ +R
Sbjct: 852 FEIVLRILAHGFIWNQIEPNRAFVYNNQNNFDLAILIISSISDLN-LYNSGYLKAFRALR 910
Query: 1317 TLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKC 1376
TLR R S+ + + ++ +L Q I + +++ V I I +I + ++ GK + C
Sbjct: 911 TLRVFSSARRGSQSEELNLISKSLFQTISLLSSMIFVTGICIWILSIFCMTIWKGKLYFC 970
Query: 1377 VDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAI 1436
++ S++ I K C + W N+ NFD + + LCLF++ +GW M
Sbjct: 971 TNVQ----SYDNIYTKQDCLDQKGEWINNITNFDTIQDSLLCLFRIIIGEGWTSQMYYVS 1026
Query: 1437 DSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMT 1496
D E G P +++ + LNLF G+II+N+ K+ +
Sbjct: 1027 DITERGMHPKVDSSANYQILYYILLFLLNIMLLNLFTGLIINNYRTIKENISNYKSL--N 1084
Query: 1497 EDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLD 1556
E Q+++ M M K ++ I +P+ + + I + I T F++II++ + LN++ + +
Sbjct: 1085 EHQREWLQMMYIMQKKNLIRLIEKPKNQFRQICYSIATYSYFELIILILLLLNLIFCSAN 1144
Query: 1557 HYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVL 1616
++T + L++IFI +F E +K A Y+Y + WN FD ++++ + L+L
Sbjct: 1145 GNSINQTTKSAFYVLDIIFITLFHIEVFIKFSAFWYYYLKDSWNKFDILLLISTDALLIL 1204
Query: 1617 SDIIE--KYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFL 1674
+ IE K F+ P ++R +RV ++L+L + ++ L+ + LP L ++ + +
Sbjct: 1205 NSEIEMPKMFMIPLIIRCLRVLNTYKILKL---NRQLKVLIDVIQEILPTLLSVVAFIII 1261
Query: 1675 VMFIFAIFGMSFFMHVKDKGGLDDVY-----------NFKTFVQSMILLFQMSTSAGWDG 1723
++ ++A+ G+ VK D Y NF+ F ++++L +++T W
Sbjct: 1262 IIIVYALIGIQTLSVVKST-SQDAQYPFYQEIGQRNKNFQNFWDAVLILIEVTTGQYWPL 1320
Query: 1724 VL-DGIINEEEC--DLPDN--ERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILE 1778
+ D IN+ C P++ + G G C S G Y +S+LV+ +I+I++++A+I+E
Sbjct: 1321 YMSDYTINKAGCHSQTPEDILKEGVQG-C-STFFGYFYFISFLVLIRIIMISLFLAMIIE 1378
Query: 1779 NYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHKPN 1836
+Y + + + + ++ W +DP G+ +I + + + + PPL N
Sbjct: 1379 SYQECLLENTAVINPYQIEDFFLKWSDYDPKGTGWITPEDFAFLMFEMNPPLGFKDEN 1436
Score = 49.6 bits (113), Expect = 9e-04
Identities = 42/169 (24%), Positives = 77/169 (45%), Gaps = 20/169 (11%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILM------IMPTTPTVEST-EVIFTGIYT 178
P N R++ I + F L I+ +L+N I I TT + ++IF ++
Sbjct: 1109 PKNQFRQICYSIATYSYFELIILILLLLNLIFCSANGNSINQTTKSAFYVLDIIFITLFH 1168
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVI----ALAYVTMGIDLGNL----AALRTF 230
E +K A + YL+D+WN D +++ AL + I++ + +R
Sbjct: 1169 IEVFIKFSAFWYY-----YLKDSWNKFDILLLISTDALLILNSEIEMPKMFMIPLIIRCL 1223
Query: 231 RVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQ 279
RVL K + + LK ++ + E + L V+ + + V+AL+G+Q
Sbjct: 1224 RVLNTYKILKLNRQLKVLIDVIQEILPTLLSVVAFIIIIIIVYALIGIQ 1272
Score = 47.2 bits (107), Expect = 0.005
Identities = 35/152 (23%), Positives = 75/152 (49%), Gaps = 11/152 (7%)
Query: 144 SLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMARGFI---LQP-FTYLR 199
S+ I+ IL+ L I ++ +IFT I+ FE ++++A GFI ++P ++
Sbjct: 817 SIIILNIILLGMDLPIFEQKDLIQKFNLIFTIIFIFEIVLRILAHGFIWNQIEPNRAFVY 876
Query: 200 DAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIV------PGLKTIVGAVI 253
+ N D ++ ++ ++ ++L N L+ FR LR L+ + L I ++
Sbjct: 877 NNQNNFDLAILIISSIS-DLNLYNSGYLKAFRALRTLRVFSSARRGSQSEELNLISKSLF 935
Query: 254 ESVKNLRDVIILTMFSLSVFALMGLQIYMGVL 285
+++ L +I +T + + ++ + I+ G L
Sbjct: 936 QTISLLSSMIFVTGICIWILSIFCMTIWKGKL 967
Score = 46.0 bits (104), Expect = 0.011
Identities = 71/298 (23%), Positives = 121/298 (40%), Gaps = 50/298 (16%)
Query: 130 IRRVAIYILVHPLFSLFIITTILV------NCILMIMPTTPTVESTEVIFTGIYTFESAV 183
I + ++ VH L S+ ++ ++V N L I + + + I++ + +
Sbjct: 96 ISQSKLFQWVHSLLSVIVVCVLIVKPYNNENSGLNISISNAVINGIIISCDVIFSIQVVI 155
Query: 184 KVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVP 243
+++ G + Y +D + +++ + + A + L AL + K IV
Sbjct: 156 SIISYGIWNCNYGYYKDPYAFINSICLLFALILRQSYLYIFRALFLVDFIVQTKYFQIVK 215
Query: 244 GLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLT 303
L V + + VII+T+ + ++A MG+QI+ L CVK DG
Sbjct: 216 KLSNTVKHALMMTAYV--VIIITLLTY-IYATMGVQIWSDQLHHYCVK----DGD----I 264
Query: 304 DENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNP--NYGYTSFDTFG 361
D R C G G +C GYVC +G+ P Y Y SFD
Sbjct: 265 DAYPARLC-------GMGR------------KCPEGYVCQRGYFHQPFTQYDYISFDEIP 305
Query: 362 WAFLSAFRLMTQDYW----ENLYQLF--FVVIIFL------GSFYLVNLILAIVAMSY 407
L+ F + W +NL F ++ IFL G+F+L NL++AI+ Y
Sbjct: 306 NGLLTLFICHFIEGWVEVEQNLADTFNKYISSIFLWSYIIIGTFFLQNLLVAILLNQY 363
Score = 38.7 bits (86), Expect = 1.6
Identities = 33/166 (19%), Positives = 78/166 (46%), Gaps = 6/166 (3%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
L++K ++ + + + + + + + +L D H I+ ++ +F I+ +E
Sbjct: 424 LQIKLKAIVSSNFIKYFYSLLFITNLILFSLNDESAYHNDFENKIII-INIVFLFIYILE 482
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
L + +++ L+F+I +S+I + + + AFK +R L +
Sbjct: 483 DLARMYV--WKQKENKYILLLEFVIDFISIIVQLNDMSYPFVLNAFKGLRLLWFFNTQTS 540
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGK 1372
S +V++ AL ++ +I ++LV L + ++ I+G + FAG+
Sbjct: 541 WSNY---KVLLQALQKSFVNIPKLILVFLTYMIVIGILGREYFAGE 583
>UniRef50_Q23ZH4 Cluster: Cation channel family protein; n=1;
Tetrahymena thermophila SB210|Rep: Cation channel family
protein - Tetrahymena thermophila SB210
Length = 2943
Score = 221 bits (540), Expect = 2e-55
Identities = 162/607 (26%), Positives = 284/607 (46%), Gaps = 72/607 (11%)
Query: 1256 DRIFTVIFFIEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQA 1311
D FT+ F E LIK +ALGF Y + WC LDF IV+ SL++ + + + A
Sbjct: 2037 DLFFTIFFLCECLIKVIALGFILDEGSYLRDNWCQLDFFIVVSSLVDLSLS---SVNLNA 2093
Query: 1312 FKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
K +R LR LRPLR +S+ + M+++V AL+++I I N+++V L+ WL+FAI+G+ L G
Sbjct: 2094 IKILRLLRTLRPLRLLSQNKSMKLIVTALMESIGGIANMIIVVLLIWLMFAILGLNLMQG 2153
Query: 1372 KYFKCVD-------------------MNHTTLSHEIIPDKNACT-LENYTWENSPMNFDH 1411
K F C + + + + C L W+ P N D+
Sbjct: 2154 KLFYCNTTGAALSGSYNVYNYPKKQILKYIKNGFSFLTHQIKCEQLPGAFWDRYPNNSDN 2213
Query: 1412 VGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNL 1471
+G + + LF ++TF+GW + +D + G P+ + Y ++ ++NL
Sbjct: 2214 IGFSMVMLFVLSTFEGWPNYVWYYLDGSDTG--PVWNNSRYFGVFFTVFIFVGSFFSINL 2271
Query: 1472 FIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRP-QAIVF 1530
F +I NF+ KKA + F+T+DQ ++ + + P A +P + I++
Sbjct: 2272 FTAIISFNFDIATKKAKNA---FLTDDQSQWIELQRLIVKSTPDYASMKPPDNNFRKILW 2328
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL 1590
I K D+ I+ I N++ M + + S + +L +N+ F +F +EC
Sbjct: 2329 RISESPKLDIFIIFCIIGNVVVMAMAYDTSSSNYDFILQSVNLGFTGVFIAEC------- 2381
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYF----VSPTLLRVVRVAKVGRVLRLVK 1646
WN FDF VV S++ +++S + +F P + RV+RV +V R+L+L+K
Sbjct: 2382 --------WNQFDFFVVCASVVDIIMSYSGKSFFSFLKAGPQIARVLRVLRVSRLLKLIK 2433
Query: 1647 GAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFV 1706
+G++ L+ + P N LL L FIF+I F ++ L +NF F
Sbjct: 2434 SFQGLQKLIQTTVFAFPKFLNATLLFVLFYFIFSILAWFLFSDLQSGWRLSTFWNFTNFH 2493
Query: 1707 QSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFL 1766
+++ILL +MST W V+ N IG+ + +S+ +
Sbjct: 2494 RAIILLVRMSTGEDWYLVMYDTFN-----------------AKGVIGLIFFVSFYTVQSY 2536
Query: 1767 IVINMYIAVILENYSQATEDVQEGLT--DDDYDMYYEIW-QRFDPDGSQYIRYDQLSDFL 1823
I++N+++ +I+ + + + L+ ++ + + + W Q D I L++F
Sbjct: 2537 ILMNLFVLIIMNEFEENYINPDNPLSNFNEQEEQFKKRWVQMTQKDSGIKIHEKYLTEFY 2596
Query: 1824 DVLEPPL 1830
L PL
Sbjct: 2597 FELPAPL 2603
Score = 137 bits (331), Expect = 3e-30
Identities = 88/295 (29%), Positives = 155/295 (52%), Gaps = 36/295 (12%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIM--PTTPTVESTEVIFT--GIYTFESAVKV 185
I + I+ H +F++ ++ I+ N +++ PTT + + + + IYT E +K+
Sbjct: 185 ISYICFCIINHNIFTVISLSVIIFNSVMLARDDPTTNSDNNPAIDLSLLVIYTVEMGLKI 244
Query: 186 MARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLG--NLAALRTFRVLRALKTVAIVP 243
+A GFI +YL + WN LDFV+I ++ I+ NL ALR+ RVLR L++++ V
Sbjct: 245 LAMGFIFSKNSYLSEGWNVLDFVIIVTGWLPYVINSSSFNLTALRSLRVLRPLRSISKVK 304
Query: 244 GLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLT 303
L +V A+ ++ L+D I+ F VF + GLQ++ G L +C+ ++ + L
Sbjct: 305 ILNQLVTALFTAIPLLKDAFIILCFFFGVFGIAGLQLFSGQLKTRCIDIY----TGIKLG 360
Query: 304 DENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWA 363
DEN N + GD P+ Q Y+C +G +PN +FDTFGW+
Sbjct: 361 DEN------NNLFVCAQDGDCPI--------QQGISYICAKGM-VSPNSDLYNFDTFGWS 405
Query: 364 FLSAFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
L+ + +++ + W + Q ++F +I++LG++ LVNL + I+A+ Y
Sbjct: 406 LLNVYVVVSNEGWSTIMQFVMVGFNFFAFIYFFLIVYLGTWLLVNLCMGIIAVKY 460
Score = 93.1 bits (221), Expect = 7e-17
Identities = 76/299 (25%), Positives = 138/299 (46%), Gaps = 14/299 (4%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTE--VIFTGIY 177
+L++ R+ YI H + + + + + T T S + + FT +
Sbjct: 1985 SLFLFSKEGNFRKSIYYIYKHAIIIILTSFKLTFDTYIGTADVTATQFSNDADLFFTIFF 2044
Query: 178 TFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALK 237
E +KV+A GFIL +YLRD W LDF ++ + V + + NL A++ R+LR L+
Sbjct: 2045 LCECLIKVIALGFILDEGSYLRDNWCQLDFFIVVSSLVDLSLSSVNLNAIKILRLLRTLR 2104
Query: 238 TVAIV---PGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFP 294
+ ++ +K IV A++ES+ + ++II+ + +FA++GL + G L
Sbjct: 2105 PLRLLSQNKSMKLIVTALMESIGGIANMIIVVLLIWLMFAILGLNLMQGKLFYCNTTGAA 2164
Query: 295 EDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGA-GQCEPGYVCLQGFGPNPNYG 353
GS+ N+ + ++ + N + C GA P GF +
Sbjct: 2165 LSGSY-NVYNYPKKQILKYIKNGFSFLTHQIKCEQLPGAFWDRYPNNSDNIGFSMVMLFV 2223
Query: 354 YTSFD---TFGWAFLSAFRLMTQDYWEN--LYQLFFVVIIFLGSFYLVNLILAIVAMSY 407
++F+ + W +L T W N + +FF V IF+GSF+ +NL AI++ ++
Sbjct: 2224 LSTFEGWPNYVWYYLDGSD--TGPVWNNSRYFGVFFTVFIFVGSFFSINLFTAIISFNF 2280
Score = 89.8 bits (213), Expect = 7e-16
Identities = 75/247 (30%), Positives = 131/247 (53%), Gaps = 16/247 (6%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY-HYFV 1596
F+ +IML + LN + + +D + + + +LD N+IF ++F+ + LKI + Y
Sbjct: 1623 FENLIMLCVLLNTVVLCMDGIIPTSS-AYILDTFNLIFTILFAIDMGLKIIGMGLVMYAS 1681
Query: 1597 EPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLF 1656
+ N+FD V+V SI L+ + ++ R++RV +V RV RL++ + ++ L+
Sbjct: 1682 DKMNIFDAVIVSLSIFELIFLNGTSSVSALRSI-RILRVFRVLRVTRLLRSLQFMKILVT 1740
Query: 1657 ALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMS 1716
A++ +L I LLLFL+MFI+A+ GMS F GG VYN + + S + Q
Sbjct: 1741 AISSTLEQFIYILLLLFLIMFIYALLGMSLF------GGNWPVYN--SNIPSRLNYDQFI 1792
Query: 1717 TSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVI 1776
+A VLD + E D N S N S + YL+S + I I++ + +A++
Sbjct: 1793 NAA--FAVLDLLTLENWNDQLTNCLIS--NV-SNYVCTAYLISMIFIGNYILLGLVLAIM 1847
Query: 1777 LENYSQA 1783
L++++ A
Sbjct: 1848 LDSFNSA 1854
Score = 80.2 bits (189), Expect = 5e-13
Identities = 79/314 (25%), Positives = 145/314 (46%), Gaps = 46/314 (14%)
Query: 1212 FKLIENTYFETAVITMILLSSLALALED--VHLPHRPILQDILYYMDRIFTVIFFIEMLI 1269
F +I + F +++I+ +S+ LA +D + + P + D VI+ +EM +
Sbjct: 190 FCIINHNIFTVISLSVIIFNSVMLARDDPTTNSDNNPAI-------DLSLLVIYTVEMGL 242
Query: 1270 KWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLR 1325
K LA+GF Y + W LDF+I++ + +V +R+LR LRPLR
Sbjct: 243 KILAMGFIFSKNSYLSEGWNVLDFVIIVTGWLPYVINSSSFN----LTALRSLRVLRPLR 298
Query: 1326 AMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKCVDM-NHTT 1383
++S+++ + +V AL AIP + + ++ F+ +F I G+QLF+G+ +C+D+
Sbjct: 299 SISKVKILNQLVTALFTAIPLLKDAFIILCFFFGVFGIAGLQLFSGQLKTRCIDIYTGIK 358
Query: 1384 LSHE-----IIPDKNACTLE---------NYTWENSPM-NFDHVGKAYLCLFQVATFKGW 1428
L E + C ++ NS + NFD G + L ++ V + +GW
Sbjct: 359 LGDENNNLFVCAQDGDCPIQQGISYICAKGMVSPNSDLYNFDTFGWSLLNVYVVVSNEGW 418
Query: 1429 IQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAG 1488
IM + VG N + ++Y +NL +G+I ++E A
Sbjct: 419 STIMQFVM----VG------FNFFAFIYFFLIVYLGTWLLVNLCMGIIAVKYSE--SIAN 466
Query: 1489 GSLEMFMTEDQKKY 1502
S++ + +Q+ Y
Sbjct: 467 QSIQSSIKGNQEGY 480
Score = 73.7 bits (173), Expect = 5e-11
Identities = 45/169 (26%), Positives = 90/169 (53%), Gaps = 9/169 (5%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEM 1267
R+K F + + FE ++ +LL+++ L ++ + +P IL + IFT++F I+M
Sbjct: 1613 RVKGF--VMHPVFENLIMLCVLLNTVVLCMDGI-IPTSSAY--ILDTFNLIFTILFAIDM 1667
Query: 1268 LIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA- 1326
+K + +G Y ++ D +IV +S+ + L G + A +++R LR R LR
Sbjct: 1668 GLKIIGMGLVMYASDKMNIFDAVIVSLSIFELIF-LNGTSSVSALRSIRILRVFRVLRVT 1726
Query: 1327 --MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
+ +Q M+++V A+ + +LL+ + I+A++G+ LF G +
Sbjct: 1727 RLLRSLQFMKILVTAISSTLEQFIYILLLLFLIMFIYALLGMSLFGGNW 1775
Score = 62.5 bits (145), Expect = 1e-07
Identities = 41/175 (23%), Positives = 91/175 (52%), Gaps = 18/175 (10%)
Query: 123 ILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILM----IMPTTPT--VESTEVIFTGI 176
I+ IRR ++HP+F I+ +L+N +++ I+PT+ +++ +IFT +
Sbjct: 1603 IIGIIQAIRRRVKGFVMHPVFENLIMLCVLLNTVVLCMDGIIPTSSAYILDTFNLIFTIL 1662
Query: 177 YTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV-------TMGID-LGNLAALR 228
+ + +K++ G ++ Y D N D V+++L+ T + L ++ LR
Sbjct: 1663 FAIDMGLKIIGMGLVM----YASDKMNIFDAVIVSLSIFELIFLNGTSSVSALRSIRILR 1718
Query: 229 TFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
FRVLR + + + +K +V A+ +++ +++L + ++AL+G+ ++ G
Sbjct: 1719 VFRVLRVTRLLRSLQFMKILVTAISSTLEQFIYILLLLFLIMFIYALLGMSLFGG 1773
Score = 59.7 bits (138), Expect = 8e-07
Identities = 39/149 (26%), Positives = 77/149 (51%), Gaps = 13/149 (8%)
Query: 1544 LFIGLNMLTMTLDHYQQSETFSAVL--DYLNMIFIVIFSSECLLKIFALRY-----HYFV 1596
+ I L +T D Y + +A + ++ F + F ECL+K+ AL + Y
Sbjct: 2007 IIIILTSFKLTFDTYIGTADVTATQFSNDADLFFTIFFLCECLIKVIALGFILDEGSYLR 2066
Query: 1597 EPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLF 1656
+ W DF +V+ S++ L LS V+ ++++R+ + R LRL+ K ++ ++
Sbjct: 2067 DNWCQLDFFIVVSSLVDLSLSS------VNLNAIKILRLLRTLRPLRLLSQNKSMKLIVT 2120
Query: 1657 ALAMSLPALFNICLLLFLVMFIFAIFGMS 1685
AL S+ + N+ +++ L+ +FAI G++
Sbjct: 2121 ALMESIGGIANMIIVVLLIWLMFAILGLN 2149
Score = 54.0 bits (124), Expect = 4e-05
Identities = 32/124 (25%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKN 884
+ L+ LRV +L +S + +L++ + T+ + +L +I+FI+A++GM LFG N
Sbjct: 1715 RILRVFRVLRVTRLLRSLQFMKILVTAISSTLEQFIYILLLLFLIMFIYALLGMSLFGGN 1774
Query: 885 YVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCML--VGDVSCIPFFLA 941
+ Y P R N+ F+++ V +L E W + + +C++ V + C + ++
Sbjct: 1775 WPVYNSNIPS----RLNYDQFINAAFAVLDLLTLENWNDQLTNCLISNVSNYVCTAYLIS 1830
Query: 942 TVVI 945
+ I
Sbjct: 1831 MIFI 1834
Score = 50.0 bits (114), Expect = 6e-04
Identities = 43/165 (26%), Positives = 75/165 (45%), Gaps = 15/165 (9%)
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKI 1587
I F I+ F +I + I N + + D + + +D + +VI++ E LKI
Sbjct: 188 ICFCIINHNIFTVISLSVIIFNSVMLARDDPTTNSDNNPAID---LSLLVIYTVEMGLKI 244
Query: 1588 FALRY-----HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVL 1642
A+ + Y E WN+ DFV+++ L V++ S L +R +V R L
Sbjct: 245 LAMGFIFSKNSYLSEGWNVLDFVIIVTGWLPYVINS-------SSFNLTALRSLRVLRPL 297
Query: 1643 RLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
R + K + L+ AL ++P L + ++L +F I G+ F
Sbjct: 298 RSISKVKILNQLVTALFTAIPLLKDAFIILCFFFGVFGIAGLQLF 342
Score = 37.9 bits (84), Expect = 2.8
Identities = 30/110 (27%), Positives = 49/110 (44%), Gaps = 9/110 (8%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDY-VDRF 892
R+ KL KS+ L LI N T + + FIF+++ LF + + F
Sbjct: 2427 RLLKLIKSFQGLQKLIQTTVFAFPKFLNATLLFVLFYFIFSILAWFLFSDLQSGWRLSTF 2486
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSCIPFFLA 941
WNFT+F + +++ R+ GE W M+D V + FF++
Sbjct: 2487 -------WNFTNFHRAIILLVRMSTGEDWYLVMYDTFNAKGVIGLIFFVS 2529
>UniRef50_Q4S5I1 Cluster: Chromosome 3 SCAF14730, whole genome shotgun
sequence; n=6; Clupeocephala|Rep: Chromosome 3 SCAF14730,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 2040
Score = 217 bits (529), Expect = 3e-54
Identities = 130/411 (31%), Positives = 219/411 (53%), Gaps = 16/411 (3%)
Query: 1219 YFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQ- 1277
YFE ++ +I +SS+ALA ED P P ++L Y D +FT +F EMLIK + LG
Sbjct: 1084 YFEMCILLVIAMSSIALAAEDPVWPDSP-RNNVLRYFDYVFTGVFTFEMLIKMVDLGLVL 1142
Query: 1278 ---KYFTNAWCWLDFIIVMVSLINFVAALCGAG-GIQAFKTMRTLRALRPLRAMSRMQGM 1333
YF + W LDFI+V +L+ F G I K++R LR LRPL+ + R+ +
Sbjct: 1143 HQGSYFRDLWNILDFIVVSGALVAFAFTGSSKGKDISTIKSLRVLRVLRPLKTIKRLPKL 1202
Query: 1334 RVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMN---HTTLSHEIIP 1390
+ V + +V ++ ++ N+L+V L+F IFA++ VQLF G++F C D + E +
Sbjct: 1203 KAVFDCVVNSLKNVLNILIVYLLFMFIFAVVAVQLFKGRFFYCTDESKEFERDCRGEYLV 1262
Query: 1391 DKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETN 1450
N + W+ ++D+V A L LF V+T +GW Q++ ++D+ + P
Sbjct: 1263 YDNEVKAQKREWKKYDFHYDNVAWALLTLFTVSTGEGWPQVLKHSVDATYENQGPSPGYR 1322
Query: 1451 IYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMG 1510
+ M ++ +N+F+ +II F EQ K +E + E ++ +
Sbjct: 1323 MEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDK---MMEDYSLEKNER--ACIDFAI 1377
Query: 1511 SKKPL-KAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLD 1569
+ +PL + +P+ + Q ++E V F+ IM I LN + + + + S T+ AVL
Sbjct: 1378 NARPLTRHMPQNKLSFQYRMWEFVVSPPFEYTIMAMIALNTVVLMMKYDGASATYEAVLA 1437
Query: 1570 YLNMIFIVIFSSECLLKIFAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDI 1619
LN++F +FS EC+LKI A +YF + WN+FD V V+ SI ++++++
Sbjct: 1438 NLNIVFTSLFSMECVLKIIAFGALNYFKDGWNIFDCVTVLGSITDILVTEL 1488
Score = 106 bits (255), Expect = 5e-21
Identities = 56/179 (31%), Positives = 101/179 (56%), Gaps = 15/179 (8%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILM-----IMPTTP---TVESTEV 171
+++IL NP RR Y+ F + I+ I ++ I + + P +P + +
Sbjct: 1062 SMFILTTTNPFRRACHYVCTLRYFEMCILLVIAMSSIALAAEDPVWPDSPRNNVLRYFDY 1121
Query: 172 IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM-------GIDLGNL 224
+FTG++TFE +K++ G +L +Y RD WN LDF+V++ A V G D+ +
Sbjct: 1122 VFTGVFTFEMLIKMVDLGLVLHQGSYFRDLWNILDFIVVSGALVAFAFTGSSKGKDISTI 1181
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
+LR RVLR LKT+ +P LK + V+ S+KN+ +++I+ + + +FA++ +Q++ G
Sbjct: 1182 KSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYLLFMFIFAVVAVQLFKG 1240
Score = 98.7 bits (235), Expect = 1e-18
Identities = 74/287 (25%), Positives = 141/287 (49%), Gaps = 27/287 (9%)
Query: 1511 SKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDY 1570
SK R R + ++ IV + F ++ +GLN L + + HY Q E S L++
Sbjct: 342 SKLEGSTFKRRERRLRFLIRRIVKSQAFYWTVLCLVGLNTLCVAVVHYDQPEPLSDFLNF 401
Query: 1571 LNMIFIVIFSSECLLKIFAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTL 1629
+F+ IF +E +K++ L R Y +N FD +V+ SI ++ S I ++
Sbjct: 402 AEFVFLGIFLTEMFVKMYGLGRQAYLNSSFNCFDCIVICGSIFEVLWSIIQPGTSFGISV 461
Query: 1630 LRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMH 1689
LR +R+ R+ ++ K +R L+ +L S+ ++ ++ LLFL + +FA+ GM F
Sbjct: 462 LRALRLL---RIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGG 518
Query: 1690 VKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCG 1748
+ NF TF +++ +FQ+ T W+ V+ DGI ++ G
Sbjct: 519 QFNFENGTPPTNFDTFPAAIMTVFQILTGEDWNMVMYDGIKSQ----------------G 562
Query: 1749 SATIGITYLLSYLVISFL---IVINMYIAVILENYSQA---TEDVQE 1789
G+ + + ++V++ ++N+++A+ ++N + A T+D QE
Sbjct: 563 GVNKGMAFSVFFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQE 609
Score = 92.7 bits (220), Expect = 9e-17
Identities = 74/311 (23%), Positives = 137/311 (44%), Gaps = 32/311 (10%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
LR +++++ F V+ ++ L++L +A+ VH L D L + + +F IF E
Sbjct: 356 LRFLIRRIVKSQAFYWTVLCLVGLNTLCVAV--VHYDQPEPLSDFLNFAEFVFLGIFLTE 413
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
M +K LG Q Y +++ D I++ S+ + ++ G +R LR LR +
Sbjct: 414 MFVKMYGLGRQAYLNSSFNCFDCIVICGSIFEVLWSIIQPGTSFGISVLRALRLLRIFKV 473
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH 1386
+R +V +L+ ++ SI ++L + +F ++FA++G+QLF G++
Sbjct: 474 TKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQF------------- 520
Query: 1387 EIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPI 1446
EN T P NFD A + +FQ+ T + W +M D I S+ + +
Sbjct: 521 ---------NFENGT---PPTNFDTFPAAIMTVFQILTGEDWNMVMYDGIKSQGGVNKGM 568
Query: 1447 RETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAM 1506
+ ++ L LN+F+ + +DN ++ E QK
Sbjct: 569 AFSVFFIVL-----TLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAASQKLALQKA 623
Query: 1507 KKMGSKKPLKA 1517
K++ PL A
Sbjct: 624 KEVAEVSPLSA 634
Score = 65.3 bits (152), Expect = 2e-08
Identities = 43/162 (26%), Positives = 83/162 (51%), Gaps = 8/162 (4%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTL-DHYQQSETFSAVLDYLNMIFIVIFSSECLLKI--F 1588
+ T + F+M I+L I ++ + + D + VL Y + +F +F+ E L+K+
Sbjct: 1079 VCTLRYFEMCILLVIAMSSIALAAEDPVWPDSPRNNVLRYFDYVFTGVFTFEMLIKMVDL 1138
Query: 1589 ALRYH---YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLV 1645
L H YF + WN+ DF+VV ++++ + + +S ++ +RV +V R L+ +
Sbjct: 1139 GLVLHQGSYFRDLWNILDFIVVSGALVAFAFTGSSKGKDIST--IKSLRVLRVLRPLKTI 1196
Query: 1646 KGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
K ++ + + SL + NI ++ L MFIFA+ + F
Sbjct: 1197 KRLPKLKAVFDCVVNSLKNVLNILIVYLLFMFIFAVVAVQLF 1238
Score = 64.1 bits (149), Expect = 4e-08
Identities = 39/102 (38%), Positives = 63/102 (61%), Gaps = 9/102 (8%)
Query: 827 LKSGNYLRVFKLAKSWPTL-NLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY 885
L++ LR+FK+ K W +L NL++S++ +M ++ +L F+L + I +FA++GMQLFG +
Sbjct: 462 LRALRLLRIFKVTKYWASLRNLVVSLLN-SMKSIISLLFLLFLFIVVFALLGMQLFGGQF 520
Query: 886 VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWD 926
F +G P NF F + M VF++L GE W M+D
Sbjct: 521 -----NFENG-TPPTNFDTFPAAIMTVFQILTGEDWNMVMYD 556
Score = 54.4 bits (125), Expect = 3e-05
Identities = 41/149 (27%), Positives = 68/149 (45%), Gaps = 7/149 (4%)
Query: 1735 DLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDD 1794
D+ E G CGS Y +S++ +++N+++AVI++N+ T D L
Sbjct: 1482 DILVTELGVNPECGSQ-FAYLYFVSFIFFCSFLMLNLFVAVIMDNFEYLTRD-SSILGPH 1539
Query: 1795 DYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHK--PNK--YK-IISMDIPICR 1849
+ Y IW +DP I ++ D L + PPL + K P + YK ++ MD+P+
Sbjct: 1540 HLEEYVRIWAEYDPAACGRISCREMYDMLRHMCPPLGLGKRCPARVAYKRLLRMDLPVAD 1599
Query: 1850 GDMMFCVDILDALTKDFFARKGNPIEETG 1878
+ + L AL + K I E G
Sbjct: 1600 DNTVHFNSTLMALIRTALDIKIAKISEGG 1628
Score = 51.6 bits (118), Expect = 2e-04
Identities = 35/130 (26%), Positives = 63/130 (48%), Gaps = 12/130 (9%)
Query: 161 PTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIA-------LA 213
P + + E +F GI+ E VK+ G YL ++N D +VI +
Sbjct: 394 PLSDFLNFAEFVFLGIFLTEMFVKMYGLG----RQAYLNSSFNCFDCIVICGSIFEVLWS 449
Query: 214 YVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVF 273
+ G G ++ LR R+LR K L+ +V +++ S+K++ ++ L + VF
Sbjct: 450 IIQPGTSFG-ISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVF 508
Query: 274 ALMGLQIYMG 283
AL+G+Q++ G
Sbjct: 509 ALLGMQLFGG 518
Score = 39.5 bits (88), Expect = 0.91
Identities = 21/100 (21%), Positives = 52/100 (52%), Gaps = 2/100 (2%)
Query: 1206 TLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFI 1265
+ + + ++ + + FE ++ MI L+++ L ++ + + +L ++ +FT +F +
Sbjct: 1392 SFQYRMWEFVVSPPFEYTIMAMIALNTVVLMMK--YDGASATYEAVLANLNIVFTSLFSM 1449
Query: 1266 EMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCG 1305
E ++K +A G YF + W D + V+ S+ + + G
Sbjct: 1450 ECVLKIIAFGALNYFKDGWNIFDCVTVLGSITDILVTELG 1489
>UniRef50_Q4RZH4 Cluster: Chromosome undetermined SCAF14924, whole
genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome undetermined SCAF14924, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1655
Score = 213 bits (519), Expect = 5e-53
Identities = 132/382 (34%), Positives = 209/382 (54%), Gaps = 21/382 (5%)
Query: 1249 QDILYYMDRIFTVIFFIEMLIKWLALG---FQKYFTNAWC-WLDFIIVMVSLINFVAALC 1304
Q IL Y D FT IF +E+L+K G Q F W LD ++V VSL++F
Sbjct: 565 QPILGYADYAFTSIFTVEILLKMTVHGAFLHQGSFCRNWFNLLDLLVVSVSLVSF---FL 621
Query: 1305 GAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIM 1364
+ I K +R LR LRPLRA++R +G++ VV + AI +I N+++V + +FA +
Sbjct: 622 HSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACI 681
Query: 1365 GVQLFAGKYFKCVD-MNHT------TLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYL 1417
GVQLF GK+++C D HT T D + + W NS NFD+V +
Sbjct: 682 GVQLFKGKFYRCTDEAKHTPEQCKGTFVVYKDGDVSHPMVRERIWHNSDFNFDNVLMGMM 741
Query: 1418 CLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVII 1477
LF V+TF+GW ++ AID+ PI + + ++ +N+F+G +I
Sbjct: 742 ALFTVSTFEGWPALLYKAIDANGENSGPIYNYRVEISIFFIVYIIIIAFFMMNIFVGFVI 801
Query: 1478 DNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKK 1537
F EQ ++ + E+ + Q Y A+K +PLK + P+ Q + I+
Sbjct: 802 ITFREQGEQEYKNCELDKNQRQCVEY-ALK----AQPLK-LYIPKNPVQYKFWAIINSTG 855
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR-YHYFV 1596
F+ ++ + I LN +T+ + HY+QS+TFS V+D LNM+F +F+ E LLK+ ALR HYFV
Sbjct: 856 FEYVMFVLILLNTVTLAIQHYEQSKTFSHVMDILNMVFTGLFTVEMLLKLLALRPRHYFV 915
Query: 1597 EPWNLFDFVVVMFSILSLVLSD 1618
+ WN FD ++V+ S++ +V+++
Sbjct: 916 DAWNSFDALIVVGSVVDIVVTE 937
Score = 83.8 bits (198), Expect = 4e-14
Identities = 55/187 (29%), Positives = 95/187 (50%), Gaps = 11/187 (5%)
Query: 1533 VTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY 1592
V F +++L + LN +HY Q + V D N + + +F+ E LLK+++L
Sbjct: 322 VKSTTFYWVVLLLVFLNTSLSASEHYNQPLWLTQVQDIANKVLLSLFTVEMLLKMYSLGL 381
Query: 1593 -HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGI 1651
HYFV +N FD VV I+ +L +E + P + V+R ++ R+ R+ + +
Sbjct: 382 AHYFVAFFNRFDCFVVCGGIVETIL---VEMEIMPPLGISVLRCVRLLRIFRVTRHWTAL 438
Query: 1652 RTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVY----NFKTFVQ 1707
L+ +L S+ ++ ++ LLLFL + IFA+ GM F K D+ F +F Q
Sbjct: 439 SGLVASLLNSMKSIASLLLLLFLFLIIFALLGMQLF---GGKFNFDETQTKRSTFDSFPQ 495
Query: 1708 SMILLFQ 1714
+++ FQ
Sbjct: 496 ALLTCFQ 502
Score = 75.4 bits (177), Expect = 2e-11
Identities = 53/194 (27%), Positives = 100/194 (51%), Gaps = 34/194 (17%)
Query: 223 NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYM 282
++ ALR FRVLR L+ V+ VP L+ ++ ++++++ L + +L +F + ++A++GL++++
Sbjct: 30 DVKALRAFRVLRPLRLVSGVPSLQIVLNSIMKAMVPLLHIALLVLFVIIIYAIIGLELFI 89
Query: 283 GVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVC 342
G + + C + TD Y E P C + QC
Sbjct: 90 GRMHKTC---------YYTTTDN------------YVEDDPVP-CAFAGHGRQCVVNGSE 127
Query: 343 LQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQD------YWEN------LYQLFFVVIIFL 390
+G PN G T+FD F +A L+ F+ +T + YW N L ++FV ++
Sbjct: 128 CRGRWDGPNGGITNFDNFFFAMLTVFQCITMEGWTDVLYWMNDAIGFELPWVYFVSLVIF 187
Query: 391 GSFYLVNLILAIVA 404
GSF+++NL+L +++
Sbjct: 188 GSFFVLNLVLGVLS 201
Score = 68.9 bits (161), Expect = 1e-09
Identities = 51/205 (24%), Positives = 101/205 (49%), Gaps = 13/205 (6%)
Query: 1173 VDDTPADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSS 1232
+D+ +CC + C+ + ++ W +T +++T F V+ ++ L++
Sbjct: 283 IDEEHTNCC-QACWSRVMKISCCRTLRRWNRVCRRNCRT--AVKSTTFYWVVLLLVFLNT 339
Query: 1233 LALALEDVHLP-HRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFII 1291
A E + P +QDI +++ +F +EML+K +LG YF + D +
Sbjct: 340 SLSASEHYNQPLWLTQVQDIA---NKVLLSLFTVEMLLKMYSLGLAHYFVAFFNRFDCFV 396
Query: 1292 VMVSLINFVAA---LCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIF 1348
V ++ + + GI + +R LR R R + + G+ V +L+ ++ SI
Sbjct: 397 VCGGIVETILVEMEIMPPLGISVLRCVRLLRIFRVTRHWTALSGL---VASLLNSMKSIA 453
Query: 1349 NVLLVCLIFWLIFAIMGVQLFAGKY 1373
++LL+ +F +IFA++G+QLF GK+
Sbjct: 454 SLLLLLFLFLIIFALLGMQLFGGKF 478
Score = 68.1 bits (159), Expect = 2e-09
Identities = 53/200 (26%), Positives = 94/200 (47%), Gaps = 34/200 (17%)
Query: 1307 GGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGV 1366
GG+ K +R R LRPLR +S + +++V+N++++A+ + ++ L+ L +I+AI+G+
Sbjct: 27 GGLDV-KALRAFRVLRPLRLVSGVPSLQIVLNSIMKAMVPLLHIALLVLFVIIIYAIIGL 85
Query: 1367 QLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENY-------------TWE---NSPMNFD 1410
+LF G+ K +TT + + D C + W+ NFD
Sbjct: 86 ELFIGRMHK--TCYYTTTDNYVEDDPVPCAFAGHGRQCVVNGSECRGRWDGPNGGITNFD 143
Query: 1411 HVGKAYLCLFQVATFKGWIQI---MNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXX 1467
+ A L +FQ T +GW + MNDAI ++Y
Sbjct: 144 NFFFAMLTVFQCITMEGWTDVLYWMNDAIGFE------------LPWVYFVSLVIFGSFF 191
Query: 1468 TLNLFIGVIIDNFNEQKKKA 1487
LNL +GV+ F+++++KA
Sbjct: 192 VLNLVLGVLSGEFSKEREKA 211
Score = 64.9 bits (151), Expect = 2e-08
Identities = 34/123 (27%), Positives = 68/123 (55%), Gaps = 3/123 (2%)
Query: 164 PTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN 223
P + + FT I+T E +K+ G L ++ R+ +N LD +V++++ V+ +
Sbjct: 566 PILGYADYAFTSIFTVEILLKMTVHGAFLHQGSFCRNWFNLLDLLVVSVSLVSFFLHSSA 625
Query: 224 LAA---LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
++ LR RVLR L+ + GLK +V V +++ + +++I+T +FA +G+Q+
Sbjct: 626 ISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQL 685
Query: 281 YMG 283
+ G
Sbjct: 686 FKG 688
Score = 59.7 bits (138), Expect = 8e-07
Identities = 34/108 (31%), Positives = 62/108 (57%), Gaps = 5/108 (4%)
Query: 1664 ALFNICLLLFLVMFIFAIFGMSFF--MHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGW 1721
AL + LL+ ++ FI+A+ GM F + ++D ++ NF+TF Q+++LLF+ +T W
Sbjct: 940 ALPYVALLIAMIFFIYAVIGMQTFGKIAMQDYTQINRNNNFQTFPQAVLLLFRCATGEAW 999
Query: 1722 DGVLDGIINEEECD-LPDNERGSPGNCGSATIGITYLLSYLVI-SFLI 1767
++ + + CD D E G +CGS I Y +S+ ++ +FL+
Sbjct: 1000 QEIMLASLPGKRCDPESDYEPGEEFSCGS-NFAIVYFISFFMLCAFLV 1046
Score = 59.3 bits (137), Expect = 1e-06
Identities = 30/94 (31%), Positives = 57/94 (60%), Gaps = 2/94 (2%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
++ K + +I +T FE + +ILL+++ LA++ H ++ ++ +FT +F +E
Sbjct: 843 VQYKFWAIINSTGFEYVMFVLILLNTVTLAIQ--HYEQSKTFSHVMDILNMVFTGLFTVE 900
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFV 1300
ML+K LAL + YF +AW D +IV+ S+++ V
Sbjct: 901 MLLKLLALRPRHYFVDAWNSFDALIVVGSVVDIV 934
Score = 54.8 bits (126), Expect = 2e-05
Identities = 37/126 (29%), Positives = 68/126 (53%), Gaps = 11/126 (8%)
Query: 1567 VLDYLNMIFIVIFSSECLLKIFA----LRYHYFVEPW-NLFDFVVVMFSILSLVLSDIIE 1621
+L Y + F IF+ E LLK+ L F W NL D +VV S++S L
Sbjct: 567 ILGYADYAFTSIFTVEILLKMTVHGAFLHQGSFCRNWFNLLDLLVVSVSLVSFFL----- 621
Query: 1622 KYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAI 1681
+ + ++++++RV +V R LR + AKG++ ++ + +++ + NI ++ L+ F+FA
Sbjct: 622 -HSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFAC 680
Query: 1682 FGMSFF 1687
G+ F
Sbjct: 681 IGVQLF 686
Score = 48.4 bits (110), Expect = 0.002
Identities = 25/93 (26%), Positives = 49/93 (52%), Gaps = 5/93 (5%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+ LR+F++ + W L+ L++ + +M ++ +L +L + + IFA++GMQLFG +
Sbjct: 420 LRCVRLLRIFRVTRHWTALSGLVASLLNSMKSIASLLLLLFLFLIIFALLGMQLFGGKF- 478
Query: 887 DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE 919
F + R F F + + F+ G+
Sbjct: 479 ----NFDETQTKRSTFDSFPQALLTCFQERDGQ 507
Score = 45.2 bits (102), Expect = 0.018
Identities = 33/122 (27%), Positives = 61/122 (50%), Gaps = 8/122 (6%)
Query: 1766 LIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDV 1825
L +IN+++AVI++N+ T D L D + IW +DP+ I++ + L
Sbjct: 1079 LQIINLFVAVIMDNFDYLTRDWSI-LGPHRLDEFKRIWSEYDPEAKGRIKHLDVVALLRR 1137
Query: 1826 LEPPLQIHK--PNKY---KIISMDIPICRGDMMFCVDILDALTKDFFARK--GNPIEETG 1878
++PPL K P++ ++++M++P+ M+ L AL + K G P +E
Sbjct: 1138 IQPPLGFGKLCPHRVACKRLVAMNMPLNSDGMVTFNATLFALVRTALKIKTEGIPEQENE 1197
Query: 1879 DL 1880
+L
Sbjct: 1198 EL 1199
Score = 41.1 bits (92), Expect = 0.30
Identities = 19/59 (32%), Positives = 36/59 (61%)
Query: 1630 LRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
++ +R +V R LRLV G ++ +L ++ ++ L +I LL+ V+ I+AI G+ F+
Sbjct: 31 VKALRAFRVLRPLRLVSGVPSLQIVLNSIMKAMVPLLHIALLVLFVIIIYAIIGLELFI 89
Score = 40.3 bits (90), Expect = 0.52
Identities = 17/60 (28%), Positives = 36/60 (60%)
Query: 224 LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
++ LR R+LR + L +V +++ S+K++ +++L L +FAL+G+Q++ G
Sbjct: 417 ISVLRCVRLLRIFRVTRHWTALSGLVASLLNSMKSIASLLLLLFLFLIIFALLGMQLFGG 476
Score = 38.7 bits (86), Expect = 1.6
Identities = 26/79 (32%), Positives = 41/79 (51%), Gaps = 7/79 (8%)
Query: 848 LISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV-DYVDRFPDGDLPRWNFTDFM 906
++ I+ AL + ++ +I FI+AV+GMQ FGK + DY + NF F
Sbjct: 930 VVDIVVTEFSALPYVALLIAMIFFIYAVIGMQTFGKIAMQDYTQINRNN-----NFQTFP 984
Query: 907 HSFMIVFRVLCGE-WIESM 924
+ +++FR GE W E M
Sbjct: 985 QAVLLLFRCATGEAWQEIM 1003
Score = 38.3 bits (85), Expect = 2.1
Identities = 16/57 (28%), Positives = 36/57 (63%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
KAL++ LR +L P+L ++++ + + M L ++ ++ +I I+A++G++LF
Sbjct: 32 KALRAFRVLRPLRLVSGVPSLQIVLNSIMKAMVPLLHIALLVLFVIIIYAIIGLELF 88
>UniRef50_Q13936 Cluster: Voltage-dependent L-type calcium channel
subunit alpha-1C; n=31; Bilateria|Rep: Voltage-dependent
L-type calcium channel subunit alpha-1C - Homo sapiens
(Human)
Length = 2221
Score = 210 bits (514), Expect = 2e-52
Identities = 141/443 (31%), Positives = 235/443 (53%), Gaps = 42/443 (9%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEM 1267
RL+ +++ +T F ++ ILLSS++LA ED + H IL+Y D +FT IF IE+
Sbjct: 890 RLQCHRIVNDTIFTNLILFFILLSSISLAAEDP-VQHTSFRNHILFYFDIVFTTIFTIEI 948
Query: 1268 LIKWLALG---FQKYFT---------------------NAWCWLDFIIVMVSLINFVAAL 1303
+K L F FT N + LD ++V VSLI+F
Sbjct: 949 ALKILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQ- 1007
Query: 1304 CGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAI 1363
+ I K +R LR LRPLRA++R +G++ VV + AI +I N+++V + +FA
Sbjct: 1008 --SSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFAC 1065
Query: 1364 MGVQLFAGKYFKCVDMNHTTLSH---EIIPDKNA----CTLENYTWENSPMNFDHVGKAY 1416
+GVQLF GK + C D + T + I K+ ++ +WENS +FD+V A
Sbjct: 1066 IGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAM 1125
Query: 1417 LCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVI 1476
+ LF V+TF+GW +++ +IDS + PI + + ++ +N+F+G +
Sbjct: 1126 MALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFV 1185
Query: 1477 IDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDK 1536
I F EQ ++ + E+ + Q Y A+K +PL+ P+ + Q V+ +V
Sbjct: 1186 IVTFQEQGEQEYKNCELDKNQRQCVEY-ALK----ARPLRRY-IPKNQHQYKVWYVVNST 1239
Query: 1537 KFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR-YHYF 1595
F+ ++ + I LN + + + HY QS F ++ LNM+F +F+ E +LK+ A + YF
Sbjct: 1240 YFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYF 1299
Query: 1596 VEPWNLFDFVVVMFSILSLVLSD 1618
+PWN+FDF++V+ SI+ ++LS+
Sbjct: 1300 SDPWNVFDFLIVIGSIIDVILSE 1322
Score = 134 bits (325), Expect = 2e-29
Identities = 96/323 (29%), Positives = 169/323 (52%), Gaps = 58/323 (17%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM----------PTTPTVEST 169
AL L NPIRR I I+ F + I+ TI NC+ + + T +E
Sbjct: 103 ALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERV 162
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID--------- 220
E +F I+T E+ +KV+A G + P YLR+ WN LDF+++ + + ++
Sbjct: 163 EYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGAN 222
Query: 221 -LG------NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVF 273
LG ++ ALR FRVLR L+ V+ VP L+ ++ ++I+++ L + +L +F + ++
Sbjct: 223 ALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIY 282
Query: 274 ALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGA 333
A++GL+++MG + + C + ++G ++ E+ C ET G G
Sbjct: 283 AIIGLELFMGKMHKTC---YNQEGI-ADVPAEDDPSPCALET---GHG------------ 323
Query: 334 GQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWEN-LY-----------Q 381
QC+ G VC G+ P +G T+FD F +A L+ F+ +T + W + LY
Sbjct: 324 RQCQNGTVCKPGW-DGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPW 382
Query: 382 LFFVVIIFLGSFYLVNLILAIVA 404
++FV +I +GSF+++NL+L +++
Sbjct: 383 IYFVTLIIIGSFFVLNLVLGVLS 405
Score = 134 bits (323), Expect = 3e-29
Identities = 93/340 (27%), Positives = 176/340 (51%), Gaps = 29/340 (8%)
Query: 1539 DMIIMLFIGLNMLTMTLD--HYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFV 1596
+++ MLF GL + M L ++ FS D N+ +I + I + HYF
Sbjct: 1272 NILNMLFTGLFTVEMILKLIAFKPKGYFS---DPWNVFDFLIVIGSIIDVILSETNHYFC 1328
Query: 1597 EPWNLFDFVVVMFSILSLVLSDI--IEKYFVSPTL---------LRVVRVAKVGRVLRLV 1645
+ WN FD ++V+ SI+ + ++++ E SP++ + R+ +V R+++L+
Sbjct: 1329 DAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLL 1388
Query: 1646 KGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF--MHVKDKGGLDDVYNFK 1703
+GIRTLL+ S AL + LL+ ++ FI+A+ GM F + + D ++ NF+
Sbjct: 1389 SRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQ 1448
Query: 1704 TFVQSMILLFQMSTSAGWDGVLDGIINEEEC---DLPDNERGSPGNCGSATIGITYLLSY 1760
TF Q+++LLF+ +T W ++ + ++C P N CGS + + Y +S+
Sbjct: 1449 TFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGS-SFAVFYFISF 1507
Query: 1761 LVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLS 1820
++ ++IN+++AVI++N+ T D L D + IW +DP+ I++ +
Sbjct: 1508 YMLCAFLIINLFVAVIMDNFDYLTRD-WSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVV 1566
Query: 1821 DFLDVLEPPLQIHK--PNKY---KIISMDIPI-CRGDMMF 1854
L ++PPL K P++ +++SM++P+ G +MF
Sbjct: 1567 TLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMF 1606
Score = 101 bits (242), Expect = 2e-19
Identities = 71/257 (27%), Positives = 129/257 (50%), Gaps = 24/257 (9%)
Query: 1533 VTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY 1592
V F +++ + LN LT+ +HY Q + V D N + +F++E LLK+++L
Sbjct: 521 VKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGL 580
Query: 1593 H-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGI 1651
YFV +N FD VV IL +L +E +SP + V+R ++ R+ ++ + +
Sbjct: 581 QAYFVSLFNRFDCFVVCGGILETIL---VETKIMSPLGISVLRCVRLLRIFKITRYWNSL 637
Query: 1652 RTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVY----NFKTFVQ 1707
L+ +L S+ ++ ++ LLLFL + IF++ GM F K D++ F F Q
Sbjct: 638 SNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLF---GGKFNFDEMQTRRSTFDNFPQ 694
Query: 1708 SMILLFQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFL 1766
S++ +FQ+ T W+ V+ DGI+ G P G + Y + +
Sbjct: 695 SLLTVFQILTGEDWNSVMYDGIM----------AYGGPSFPG--MLVCIYFIILFICGNY 742
Query: 1767 IVINMYIAVILENYSQA 1783
I++N+++A+ ++N + A
Sbjct: 743 ILLNVFLAIAVDNLADA 759
Score = 101 bits (241), Expect = 3e-19
Identities = 87/312 (27%), Positives = 143/312 (45%), Gaps = 40/312 (12%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALAL-----EDVHLPHRPILQDILYYMDRIFTV 1261
+R ++E FE ++ I + +ALA+ ED L+ + Y IFTV
Sbjct: 113 IRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTV 172
Query: 1262 IFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVA----------ALCGAGGIQA 1311
F++++ L Y N W LDFIIV+V L + + AL G G
Sbjct: 173 EAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFD 232
Query: 1312 FKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
K +R R LRPLR +S + ++VV+N++++A+ + ++ L+ L +I+AI+G++LF G
Sbjct: 233 VKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMG 292
Query: 1372 KYFKCVDMNHTTLSHEIIPDKNACTLE--------NYT-----WE---NSPMNFDHVGKA 1415
K K D + C LE N T W+ + NFD+ A
Sbjct: 293 KMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFA 352
Query: 1416 YLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGV 1475
L +FQ T +GW ++ D+ VGR + ++Y LNL +GV
Sbjct: 353 MLTVFQCITMEGWTDVLYWVNDA--VGRD-------WPWIYFVTLIIIGSFFVLNLVLGV 403
Query: 1476 IIDNFNEQKKKA 1487
+ F+++++KA
Sbjct: 404 LSGEFSKEREKA 415
Score = 78.6 bits (185), Expect = 2e-12
Identities = 68/305 (22%), Positives = 132/305 (43%), Gaps = 31/305 (10%)
Query: 1198 SPFWQGWGTL-RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMD 1256
S +W+ W R K +++ F VI ++ L++L +A E + P+ L ++ +
Sbjct: 503 SRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNW--LTEVQDTAN 560
Query: 1257 RIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMR 1316
+ +F EML+K +LG Q YF + + D +V ++ + +R
Sbjct: 561 KALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLR 620
Query: 1317 TLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKC 1376
+R LR + + +V +L+ ++ SI ++LL+ +F +IF+++G+QLF GK+
Sbjct: 621 CVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKF--N 678
Query: 1377 VDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAI 1436
D T S FD+ ++ L +FQ+ T + W +M D I
Sbjct: 679 FDEMQTRRS----------------------TFDNFPQSLLTVFQILTGEDWNSVMYDGI 716
Query: 1437 DSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMT 1496
+ P + + +Y LN+F+ + +DN + + E
Sbjct: 717 MAYGGPSFP----GMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEE 772
Query: 1497 EDQKK 1501
+++KK
Sbjct: 773 KERKK 777
Score = 72.9 bits (171), Expect = 8e-11
Identities = 57/213 (26%), Positives = 103/213 (48%), Gaps = 20/213 (9%)
Query: 1496 TEDQKKYYNAMKKMGS----KKPLKAIPRPRWRP-QAIVFEIVTDKKFDMIIMLFIGLNM 1550
T+ +++ Y KK GS + P + P + IV K F++II+L I N
Sbjct: 79 TQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANC 138
Query: 1551 LTMTLD---HYQQSETFSAVLDYLNMIFIVIFSSECLLKIFA--LRYH---YFVEPWNLF 1602
+ + + S ++ L+ + +F++IF+ E LK+ A L +H Y WNL
Sbjct: 139 VALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLL 198
Query: 1603 DFVVVMFSILSLVLSDIIEKYFVSPTL-------LRVVRVAKVGRVLRLVKGAKGIRTLL 1655
DF++V+ + S +L + + ++ +R +V R LRLV G ++ +L
Sbjct: 199 DFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVL 258
Query: 1656 FALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
++ ++ L +I LL+ V+ I+AI G+ FM
Sbjct: 259 NSIIKAMVPLLHIALLVLFVIIIYAIIGLELFM 291
Score = 72.9 bits (171), Expect = 8e-11
Identities = 39/138 (28%), Positives = 76/138 (55%), Gaps = 3/138 (2%)
Query: 151 ILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVI 210
I+ I I + + + +FT I+T E +K+ A G L ++ R+ +N LD +V+
Sbjct: 938 IVFTTIFTIEIALKILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVV 997
Query: 211 ALAYVTMGID---LGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTM 267
+++ ++ GI + + LR RVLR L+ + GLK +V V +++ + +++I+T
Sbjct: 998 SVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTT 1057
Query: 268 FSLSVFALMGLQIYMGVL 285
+FA +G+Q++ G L
Sbjct: 1058 LLQFMFACIGVQLFKGKL 1075
Score = 60.9 bits (141), Expect = 3e-07
Identities = 34/118 (28%), Positives = 63/118 (53%), Gaps = 6/118 (5%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+ LR+FK+ + W +L+ L++ + ++ ++ +L +L + I IF+++GMQLFG +
Sbjct: 619 LRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKF- 677
Query: 887 DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSCIPFFLATV 943
F + R F +F S + VF++L GE W M+D ++ P L +
Sbjct: 678 ----NFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCI 731
Score = 56.4 bits (130), Expect = 7e-06
Identities = 74/323 (22%), Positives = 141/323 (43%), Gaps = 76/323 (23%)
Query: 1210 KTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLI 1269
K + ++ +TYFE + +ILL+++ LA++ H + + + ++ +FT +F +EM++
Sbjct: 1231 KVWYVVNSTYFEYLMFVLILLNTICLAMQ--HYGQSCLFKIAMNILNMLFTGLFTVEMIL 1288
Query: 1270 K-------------WLALGF---------------QKYFTNAWCWLDFIIVMVSLINF-V 1300
K W F YF +AW D +IV+ S+++ +
Sbjct: 1289 KLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAI 1348
Query: 1301 AALCGAGGIQAFKTM-------------RTLRALRPLRAMSRMQGMRVVVNALVQAIPSI 1347
+ A Q +M R R +R ++ +SR +G+R ++ +++ ++
Sbjct: 1349 TEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1408
Query: 1348 FNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPM 1407
V L+ ++ + I+A++G+Q+F GK + +N TT EI N
Sbjct: 1409 PYVALLIVMLFFIYAVIGMQVF-GK----IALNDTT---EI---------------NRNN 1445
Query: 1408 NFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVG--RQPIRET-------NIYMYLYXX 1458
NF +A L LF+ AT + W IM + ++ +P T + + Y
Sbjct: 1446 NFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFI 1505
Query: 1459 XXXXXXXXXTLNLFIGVIIDNFN 1481
+NLF+ VI+DNF+
Sbjct: 1506 SFYMLCAFLIINLFVAVIMDNFD 1528
Score = 54.4 bits (125), Expect = 3e-05
Identities = 46/177 (25%), Positives = 91/177 (51%), Gaps = 22/177 (12%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETF-SAVLDYLNMIFIVIFSSECLLKIFAL 1590
IV D F +I+ FI L+ +++ + Q +F + +L Y +++F IF+ E LKI
Sbjct: 896 IVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGN 955
Query: 1591 RYHYFVEPWNLFDFVVVM----------------FSILSL-VLSDIIEKYFVSPTLLRVV 1633
+ F + L + ++ M F+IL L V+S + + + + + VV
Sbjct: 956 ADYVFTSIFTL-EIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVV 1014
Query: 1634 RVAKVGRVLRLVKG---AKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
++ +V RVLR ++ AKG++ ++ + +++ + NI ++ L+ F+FA G+ F
Sbjct: 1015 KILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLF 1071
Score = 43.6 bits (98), Expect = 0.056
Identities = 27/97 (27%), Positives = 49/97 (50%), Gaps = 5/97 (5%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
+R+ KL + L+ ++ AL + ++ ++ FI+AV+GMQ+FGK ++
Sbjct: 1382 MRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEI 1441
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
+ NF F + +++FR GE W + M CM
Sbjct: 1442 NRNN----NFQTFPQAVLLLFRCATGEAWQDIMLACM 1474
Score = 40.3 bits (90), Expect = 0.52
Identities = 16/60 (26%), Positives = 36/60 (60%)
Query: 224 LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
++ LR R+LR K L +V +++ SV+++ +++L + +F+L+G+Q++ G
Sbjct: 616 ISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGG 675
Score = 38.3 bits (85), Expect = 2.1
Identities = 20/75 (26%), Positives = 44/75 (58%), Gaps = 1/75 (1%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF-GK 883
KAL++ LR +L P+L ++++ + + M L ++ ++ +I I+A++G++LF GK
Sbjct: 234 KALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGK 293
Query: 884 NYVDYVDRFPDGDLP 898
+ ++ D+P
Sbjct: 294 MHKTCYNQEGIADVP 308
>UniRef50_Q4STU7 Cluster: Chromosome undetermined SCAF14113, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14113,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 794
Score = 210 bits (513), Expect = 3e-52
Identities = 111/190 (58%), Positives = 137/190 (72%), Gaps = 14/190 (7%)
Query: 213 AYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSV 272
AYVT +DLGN++ALRTFRVLRALKT++++PGLKTIVGA+I+SVK L DV+ILT+F LSV
Sbjct: 310 AYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLADVMILTVFCLSV 369
Query: 273 FALMGLQIYMGVLTQKCVKV--------FPEDGSW--GNLTDENWERFCQNETNWYGEGG 322
FAL+GLQ++MG L QKCV+ P + S+ N T + + F +E N+Y G
Sbjct: 370 FALIGLQLFMGNLRQKCVRTTAHCVNGSLPANASFFCNNKTWSSMKDFVNDEENFYKVEG 429
Query: 323 --DYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLY 380
D +CGNSS AG+C G+ CL+ G NPNYGYTSFDTFGWAFLS FRLMTQD WE LY
Sbjct: 430 AKDALICGNSSDAGKCPDGFECLKA-GRNPNYGYTSFDTFGWAFLSLFRLMTQDCWETLY 488
Query: 381 -QLFFVVIIF 389
Q+ F F
Sbjct: 489 HQVMFPAPFF 498
Score = 92.3 bits (219), Expect = 1e-16
Identities = 44/78 (56%), Positives = 51/78 (65%), Gaps = 1/78 (1%)
Query: 142 LFSLFIITTILVNCILMIMPTTPT-VESTEVIFTGIYTFESAVKVMARGFILQPFTYLRD 200
LFSLFI+ TIL NC M M + E FTGIYTFES +K++ARGF + PFT+LRD
Sbjct: 197 LFSLFIMCTILTNCCFMAMSEPANWAKYLEYTFTGIYTFESLIKILARGFCVGPFTFLRD 256
Query: 201 AWNWLDFVVIALAYVTMG 218
WNWLDF VI T G
Sbjct: 257 PWNWLDFSVIVSPAATRG 274
Score = 62.9 bits (146), Expect = 9e-08
Identities = 26/39 (66%), Positives = 35/39 (89%)
Query: 102 TFVVISKGKDIFRFSATNALWILDPFNPIRRVAIYILVH 140
TF+V++KGK IFRFSAT+AL++ PF+P+RR+AI ILVH
Sbjct: 120 TFIVLNKGKAIFRFSATSALYVFSPFHPVRRIAIKILVH 158
Score = 53.6 bits (123), Expect = 5e-05
Identities = 30/107 (28%), Positives = 57/107 (53%), Gaps = 5/107 (4%)
Query: 1299 FVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFW 1358
+V G + A +T R LRAL+ + S + G++ +V AL+Q++ + +V+++ +
Sbjct: 311 YVTEFVDLGNVSALRTFRVLRALKTI---SVIPGLKTIVGALIQSVKKLADVMILTVFCL 367
Query: 1359 LIFAIMGVQLFAGKY-FKCVDMNHTTLSHEIIPDKNACTLENYTWEN 1404
+FA++G+QLF G KCV ++ +P + N TW +
Sbjct: 368 SVFALIGLQLFMGNLRQKCVRTTAHCVNGS-LPANASFFCNNKTWSS 413
Score = 52.8 bits (121), Expect = 9e-05
Identities = 22/28 (78%), Positives = 27/28 (96%)
Query: 380 YQLFFVVIIFLGSFYLVNLILAIVAMSY 407
Y +FFVV+IFLGSFYL+NLILA+VAM+Y
Sbjct: 545 YMVFFVVVIFLGSFYLINLILAVVAMAY 572
Score = 40.3 bits (90), Expect = 0.52
Identities = 20/37 (54%), Positives = 21/37 (56%), Gaps = 1/37 (2%)
Query: 61 PQPDATLEQGLPLPVRMQGSFPLELASTPLEDIDPFY 97
PQP LE G LP R+ P L PLEDIDPFY
Sbjct: 49 PQPRPDLEAGKQLP-RIFADIPSHLVGVPLEDIDPFY 84
Score = 37.5 bits (83), Expect = 3.7
Identities = 18/65 (27%), Positives = 35/65 (53%)
Query: 1624 FVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFG 1683
FV + +R +V R L+ + G++T++ AL S+ L ++ +L + +FA+ G
Sbjct: 315 FVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLADVMILTVFCLSVFALIG 374
Query: 1684 MSFFM 1688
+ FM
Sbjct: 375 LQLFM 379
>UniRef50_Q4DZ99 Cluster: Calcium channel protein, putative; n=2;
Trypanosoma|Rep: Calcium channel protein, putative -
Trypanosoma cruzi
Length = 2725
Score = 206 bits (504), Expect = 4e-51
Identities = 151/646 (23%), Positives = 306/646 (47%), Gaps = 40/646 (6%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDI-LYYMDRIFTVIFFIEMLIKWL 1272
++E+ +FE ++ +I +S+ L R + + L+ +D IF +IF +EM++KW+
Sbjct: 1790 IVESKWFEWFILAVIFAASICLCFYSPEDEDRTSKKYLALHILDDIFAIIFAVEMVLKWI 1849
Query: 1273 ALGFQ-----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAM 1327
++G YF + W D I ++SLI + K MR R L P+R
Sbjct: 1850 SMGVVLDCHVAYFWHRWNTFDCFITIISLIAIAPKY---SHFRFLKVMRCFRILGPMRYC 1906
Query: 1328 SRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHE 1387
+ + + + ++P++ NVLL+ L+ +++++I+ ++LF G + H+ SH
Sbjct: 1907 RFNKELSKLALTMWDSVPTLVNVLLLFLLNYIVWSILALRLFMG-------LTHSCTSH- 1958
Query: 1388 IIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIR 1447
+K +C W NFD+ ++ L +F+V+T W+ ++ +D + +PI
Sbjct: 1959 AFSNKTSCEEAGAMWLGPQRNFDNFYESLLTMFEVSTGSRWLDVIYTGVDGWSMEFEPIY 2018
Query: 1448 ETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMK 1507
+ L+ +LF+ +I + K A G + +T + + + +
Sbjct: 2019 NRHPSKGLFFVAYYYVSHFVLFSLFVASLIYCYLLAKNAAEGVTD--ITFEHQLWLRMQR 2076
Query: 1508 KMGSKKP-LKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSA 1566
+ +P ++ +P + + IV F++++ + NM+TM+L Y S
Sbjct: 2077 MILRLRPRVELVPLGNCLSR-FLHRIVIHPAFELVMAGILLCNMITMSLYWYGNSSRQEK 2135
Query: 1567 VLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVS 1626
LD L +++ F+ E L+K+ A F F V S L + L+ + +
Sbjct: 2136 ALDILEHLWVAFFTLEILMKLTAHGLRAFSRYSFCFQVFVTSLSYLQIGLNTTVGNHV-- 2193
Query: 1627 PTLLRVVRVAKVGRVLRLVKGAKGIRTLLF----ALAMSLPALFNICLLLFLVMFIFAIF 1682
P + +R+ +GR+L+LV +R L AL +S +L N+ L+L L +F+FA+
Sbjct: 2194 PFNVNTLRLLHLGRMLKLVDFLVPVRHHLHLLHEALLLSASSLVNVTLILALAVFVFAVL 2253
Query: 1683 GMSFFMHVKDKGG--LDDVY-NFKTFVQSMILLFQMSTSAGWDGVLDGIINE-EECDLPD 1738
GM F V G +DD Y NF+TF +++++F+++T W +L +++ C + D
Sbjct: 2254 GMHFIGPVVPVAGQYIDDTYNNFRTFPNALMMIFRLATLEDWVSMLRSSMSDGNNCPISD 2313
Query: 1739 NERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDM 1798
C + + + ++ L+++N+Y+AV++++Y +D
Sbjct: 2314 --------CKTTNWAPVFYVPIVICFALMIVNLYLAVVVDHYVTVVRMKASVARINDLRR 2365
Query: 1799 YYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQI-HKPNKYKIISM 1843
+ ++W DP+ + +R +L + L+ L PPL + + N+ +++ +
Sbjct: 2366 FRDLWSARDPNATLLLRTRKLPELLEALRPPLGLSSRKNRAELLRL 2411
Score = 113 bits (272), Expect = 5e-23
Identities = 70/214 (32%), Positives = 106/214 (49%), Gaps = 20/214 (9%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV--TMGIDLGNLAAL 227
+ ++T +Y E ++ A G IL Y R W+WLD V L + T DL N A
Sbjct: 391 DFLYTILYGIEIIARLFASGCILHSRAYFRSPWHWLDTAVFVLMIMNCTQWRDLWNFTAF 450
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQ 287
R R+++A + + +K I +V+ S L I+ +++L FAL+GLQ++ GVL
Sbjct: 451 RLIRIIKACTYLPLPIRMKIIAKSVLRSTCKLFQTSIILVYALFFFALLGLQLFRGVLHY 510
Query: 288 KCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFG 347
+CV +LT + C+ E G + G+ C+PGY+C+
Sbjct: 511 RCV---------NSLTGAATSQLCRPEAT----GHYWFYWGH-----VCDPGYICISDGF 552
Query: 348 PNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ 381
PNPNY + SFD G A LS F++MT W +L Q
Sbjct: 553 PNPNYDFRSFDDVGHALLSTFQIMTFQGWTSLLQ 586
Score = 70.1 bits (164), Expect = 6e-10
Identities = 55/253 (21%), Positives = 116/253 (45%), Gaps = 26/253 (10%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEM 1267
R+ T+ ++ + E ++ +IL S+ A + D + + D ++T+++ IE+
Sbjct: 343 RVVTYNVLHHWLMELMILLIILGYSIFTASWSRYGAPEFEKPDFMVFADFLYTILYGIEI 402
Query: 1268 LIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRP 1323
+ + A G + YF + W WLD + ++ ++N AF+ +R ++A
Sbjct: 403 IARLFASGCILHSRAYFRSPWHWLDTAVFVLMIMN-CTQWRDLWNFTAFRLIRIIKACTY 461
Query: 1324 LRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG-KYFKCVD-MNH 1381
L RM +++ +++++ +F ++ + FA++G+QLF G +++CV+ +
Sbjct: 462 LPLPIRM---KIIAKSVLRSTCKLFQTSIILVYALFFFALLGLQLFRGVLHYRCVNSLTG 518
Query: 1382 TTLSHEIIPDKNA---------------CTLENYTWENSPM-NFDHVGKAYLCLFQVATF 1425
S P+ C + + N +FD VG A L FQ+ TF
Sbjct: 519 AATSQLCRPEATGHYWFYWGHVCDPGYICISDGFPNPNYDFRSFDDVGHALLSTFQIMTF 578
Query: 1426 KGWIQIMNDAIDS 1438
+GW ++ + D+
Sbjct: 579 QGWTSLLQETNDA 591
Score = 50.0 bits (114), Expect = 6e-04
Identities = 41/184 (22%), Positives = 80/184 (43%), Gaps = 15/184 (8%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVEST---------- 169
+ +I P +P RR I+ F FI+ I I + + + T
Sbjct: 1773 SFFIFSPSHPARRFLTAIVESKWFEWFILAVIFAASICLCFYSPEDEDRTSKKYLALHIL 1832
Query: 170 EVIFTGIYTFESAVKVMARGFILQ-PFTYLRDAWNWLDFVVIALAYVTMGIDLGN---LA 225
+ IF I+ E +K ++ G +L Y WN D + ++ + + + L
Sbjct: 1833 DDIFAIIFAVEMVLKWISMGVVLDCHVAYFWHRWNTFDCFITIISLIAIAPKYSHFRFLK 1892
Query: 226 ALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVL 285
+R FR+L ++ L + + +SV L +V++L + + V++++ L+++MG L
Sbjct: 1893 VMRCFRILGPMRYCRFNKELSKLALTMWDSVPTLVNVLLLFLLNYIVWSILALRLFMG-L 1951
Query: 286 TQKC 289
T C
Sbjct: 1952 THSC 1955
Score = 41.1 bits (92), Expect = 0.30
Identities = 35/157 (22%), Positives = 69/157 (43%), Gaps = 13/157 (8%)
Query: 1540 MIIMLFIGLNMLTMTLDHYQQSETFSA-VLDYLNMIFIVIFSSECLLKIFALR--YH--- 1593
MI+++ +G ++ T + Y E + + + ++ +++ E + ++FA H
Sbjct: 358 MILLIILGYSIFTASWSRYGAPEFEKPDFMVFADFLYTILYGIEIIARLFASGCILHSRA 417
Query: 1594 YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRT 1653
YF PW+ D V + I++ + + T R++R+ K L L K I
Sbjct: 418 YFRSPWHWLDTAVFVLMIMNCTQWRDLWNF----TAFRLIRIIKACTYLPLPIRMKIIAK 473
Query: 1654 LLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHV 1690
++ S LF ++L +F FA+ G+ F V
Sbjct: 474 ---SVLRSTCKLFQTSIILVYALFFFALLGLQLFRGV 507
Score = 41.1 bits (92), Expect = 0.30
Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 4/89 (4%)
Query: 845 LNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTD 904
L+LL + + +L N+T +L + +F+FAV+GM G V ++ D NF
Sbjct: 2222 LHLLHEALLLSASSLVNVTLILALAVFVFAVLGMHFIGP-VVPVAGQYIDDTYN--NFRT 2278
Query: 905 FMHSFMIVFRVLCGE-WIESMWDCMLVGD 932
F ++ M++FR+ E W+ + M G+
Sbjct: 2279 FPNALMMIFRLATLEDWVSMLRSSMSDGN 2307
>UniRef50_O42421 Cluster: Voltage-gated sodium channel SNS; n=2;
Gallus gallus|Rep: Voltage-gated sodium channel SNS -
Gallus gallus (Chicken)
Length = 207
Score = 206 bits (502), Expect = 6e-51
Identities = 115/209 (55%), Positives = 145/209 (69%), Gaps = 20/209 (9%)
Query: 209 VIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMF 268
VI +A+V +LG+++ LRTFRVLRALKT+++VPGLK IVGA+I+SVK L +V+ILT+F
Sbjct: 2 VIIMAFVGAFSNLGSVSVLRTFRVLRALKTISVVPGLKIIVGALIQSVKKLANVMILTVF 61
Query: 269 SLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGN-LTDENWE---RFCQNETNWYGEGG-- 322
LSVFAL+GLQ++ G L KCVK D + + L ++ WE ++ + G
Sbjct: 62 CLSVFALIGLQLFKGNLRYKCVKKNHTDSTIRDFLRNKTWESSATLADYAEHFAIKPGTS 121
Query: 323 DYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ- 381
D LCG GAG C P + C Q GPNP+YG+TSFDTFGWAFLS FRLMTQDYWE LYQ
Sbjct: 122 DVLLCG--PGAGTCPPEHTCKQ-IGPNPDYGFTSFDTFGWAFLSLFRLMTQDYWERLYQQ 178
Query: 382 ----------LFFVVIIFLGSFYLVNLIL 400
LFF+++IFLGSFYLVNLIL
Sbjct: 179 TLRASGRVYILFFMLVIFLGSFYLVNLIL 207
Score = 70.9 bits (166), Expect = 3e-10
Identities = 41/119 (34%), Positives = 67/119 (56%), Gaps = 11/119 (9%)
Query: 1294 VSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLV 1353
V ++ FV A G + +T R LRAL+ + S + G++++V AL+Q++ + NV+++
Sbjct: 2 VIIMAFVGAFSNLGSVSVLRTFRVLRALKTI---SVVPGLKIIVGALIQSVKKLANVMIL 58
Query: 1354 CLIFWLIFAIMGVQLFAGKY-FKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDH 1411
+ +FA++G+QLF G +KCV NHT I D L N TWE+S D+
Sbjct: 59 TVFCLSVFALIGLQLFKGNLRYKCVKKNHT---DSTIRD----FLRNKTWESSATLADY 110
>UniRef50_UPI00015A3E26 Cluster: UPI00015A3E26 related cluster; n=1;
Danio rerio|Rep: UPI00015A3E26 UniRef100 entry - Danio
rerio
Length = 964
Score = 202 bits (494), Expect = 6e-50
Identities = 128/444 (28%), Positives = 234/444 (52%), Gaps = 20/444 (4%)
Query: 1422 VATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFN 1481
V+TF+GW ++ AIDS + PI + + ++ +N+F+G +I F
Sbjct: 1 VSTFEGWPALLYKAIDSSKENIGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQ 60
Query: 1482 EQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKA-IPRPRWRPQAIVFEIVTDKKFDM 1540
EQ +K + E+ + Q Y A+K +PL+ IP+ R+ Q + +V F+
Sbjct: 61 EQGEKEYKNCELDKNQRQCVEY-ALKA----RPLRRYIPKNRY--QYKFWYVVNSTGFEY 113
Query: 1541 IIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR-YHYFVEPW 1599
I I N+ + + H+ QS F+ +D LNM+F +F+ E +LK+ A + HYF + W
Sbjct: 114 ICFKAILGNISCLEIQHHGQSRLFNYAMDVLNMVFTGVFAVEMILKLVAFKPKHYFADAW 173
Query: 1600 NLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALA 1659
N FD ++V+ SI+ + +++I + + R+ +V R+++L+ +GIRTLL+
Sbjct: 174 NTFDALIVVGSIVDIAITEINNTEDSARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFI 233
Query: 1660 MSLPALFNICLLLFLVMFIFAIFGMSFFMHVK--DKGGLDDVYNFKTFVQSMILLFQMST 1717
S AL + LL+ ++ FI+A+ GM F + D ++ NF+TF Q+++LLF+ +T
Sbjct: 234 KSFQALPYVALLIAMLFFIYAVIGMQVFGKIAMVDGTSINRNNNFQTFPQAVLLLFRCAT 293
Query: 1718 SAGWDGVLDGIINEEECDLP-DNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVI 1776
W ++ + + CD D G +CGS I Y +S+ ++ ++IN+++AVI
Sbjct: 294 GEAWQQIMLACLPGKLCDSESDYNPGEEKSCGS-NFAILYFISFYMLCAFLIINLFVAVI 352
Query: 1777 LENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHK-- 1834
++N+ T D L D + IW +DP+ I++ + L ++PPL K
Sbjct: 353 MDNFDYLTRD-WSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLC 411
Query: 1835 PNKY---KIISMDIPI-CRGDMMF 1854
P++ ++++M++P+ G +MF
Sbjct: 412 PHRVACKRLVAMNMPLNSDGTVMF 435
Score = 69.3 bits (162), Expect = 1e-09
Identities = 66/282 (23%), Positives = 126/282 (44%), Gaps = 35/282 (12%)
Query: 1210 KTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLI 1269
K + ++ +T FE IL + L ++ H + + ++ +FT +F +EM++
Sbjct: 101 KFWYVVNSTGFEYICFKAILGNISCLEIQ--HHGQSRLFNYAMDVLNMVFTGVFAVEMIL 158
Query: 1270 KWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQA---FKTMRTLRALRPLRA 1326
K +A + YF +AW D +IV+ S+++ A R R +R ++
Sbjct: 159 KLVAFKPKHYFADAWNTFDALIVVGSIVDIAITEINNTEDSARISITFFRLFRVMRLVKL 218
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH 1386
+SR +G+R ++ +++ ++ V L+ + + I+A++G+Q+F K ++ T++
Sbjct: 219 LSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFG----KIAMVDGTSI-- 272
Query: 1387 EIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSR----EVG 1442
N NF +A L LF+ AT + W QIM + + E
Sbjct: 273 -----------------NRNNNFQTFPQAVLLLFRCATGEAWQQIMLACLPGKLCDSESD 315
Query: 1443 RQPIRETNI---YMYLYXXXXXXXXXXXTLNLFIGVIIDNFN 1481
P E + + LY +NLF+ VI+DNF+
Sbjct: 316 YNPGEEKSCGSNFAILYFISFYMLCAFLIINLFVAVIMDNFD 357
Score = 55.2 bits (127), Expect = 2e-05
Identities = 32/120 (26%), Positives = 66/120 (55%), Gaps = 13/120 (10%)
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGN------ 223
++FTG++ E +K++A +P Y DAWN D +++ + V + I ++ N
Sbjct: 146 MVFTGVFAVEMILKLVA----FKPKHYFADAWNTFDALIVVGSIVDIAITEINNTEDSAR 201
Query: 224 --LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+ R FRV+R +K ++ G++T++ I+S + L V +L ++A++G+Q++
Sbjct: 202 ISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVF 261
Score = 41.5 bits (93), Expect = 0.23
Identities = 28/97 (28%), Positives = 49/97 (50%), Gaps = 5/97 (5%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
+R+ KL + L+ ++ AL + ++ ++ FI+AV+GMQ+FGK + VD
Sbjct: 213 MRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQVFGK--IAMVDGT 270
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
NF F + +++FR GE W + M C+
Sbjct: 271 SIN--RNNNFQTFPQAVLLLFRCATGEAWQQIMLACL 305
>UniRef50_A4RQQ5 Cluster: VIC family transporter: calcium ion channel;
n=2; Ostreococcus|Rep: VIC family transporter: calcium
ion channel - Ostreococcus lucimarinus CCE9901
Length = 1546
Score = 200 bits (489), Expect = 2e-49
Identities = 157/678 (23%), Positives = 302/678 (44%), Gaps = 30/678 (4%)
Query: 1167 GADEDVVDDTPADCCPEQCYQKFPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVIT 1226
G E + +D + P+ DD + G LR +++ + ++E +
Sbjct: 776 GRVEIIFEDAVSKATDFAACPALPWYISDDALCIFPSSGKLRTTLRRVLRSRWYERISFS 835
Query: 1227 MILLSSLA-LALEDVHLPH--RPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNA 1283
+++S LA LA + V + + + Y + F V F + ++ L L +
Sbjct: 836 FVVVSVLAVLATKPVDQINELQKHVDTANYAVCGFFLVDFIMNIIAHGLILTPAPFVGRV 895
Query: 1284 WCWLDFIIVMVSLINFVAALCGAGGIQAF--KTMRTLRALRPLRAMSRMQGMRVVVNALV 1341
W D I+++ ++ L + + +RP+R M+R+ M+ +V LV
Sbjct: 896 WNVFDMAILIIDVMIVACPLILGDAYTRYWRRAFNMAAPMRPIRIMTRVTSMQRLVKTLV 955
Query: 1342 QAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPD--KNACTLEN 1399
+P+I ++++ +L FAI+ ++ + G ++ C D+ T E + +
Sbjct: 956 VTLPTISGIIMLTGGMFLAFAIVAIREYGGTFYSCNDLMVMT-KIECVGTFVSTGGDIIA 1014
Query: 1400 YTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXX 1459
W + FD +G A L L + A+ GWI++M A+D VG QP E N +
Sbjct: 1015 REWNRNLFEFDWIGSAMLTLLETASLDGWIEVMFAAMDKTGVGMQPRFERNWPAAFFFVA 1074
Query: 1460 XXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIP 1519
+ IGV I F +G L +TE QK +++ K S KP++
Sbjct: 1075 FILIGSFLMIRTIIGVFIHQFG---LISGRKL---LTERQKLWHDMHKVALSLKPMRMKF 1128
Query: 1520 RPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMI-FIVI 1578
P + + F IV + + +++ +GLN M + Y E+ A + + I F+ +
Sbjct: 1129 LPPRGLRRVCFHIVNHRSYRAFVLIGVGLNAALMATERYGDGESVLAHVRSIGEICFVGV 1188
Query: 1579 FSSECLLKIFALR---YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRV 1635
+ E LL++ A HYF WN F+ + + S ++L ++ R
Sbjct: 1189 YLIEVLLQVSAAYPSVRHYFSNKWNAFELTLAVGSAVTLQSK-------AGSLRDQIGRP 1241
Query: 1636 AKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGG 1695
+ RV R+++ + ++ L L +++P++ ++ L+ + MF++A G F +VK
Sbjct: 1242 FRFLRVFRIIRHVQSLQILASTLLLAIPSILSVMGLMLIWMFMYAGIGTQIFPNVKFGEA 1301
Query: 1696 LDDVYNFKTFVQSMILLFQMSTSAGW-DGVLDGIINEEECDLPDNERGSPGNCGSATIGI 1754
L+ NF+TF S +LLFQ+ T GW + D ++ +C +E S +CG +
Sbjct: 1302 LNKDANFQTFTSSFLLLFQVITGEGWRQYMYDLMVTTPDC--THSEASS--DCGFPDGAV 1357
Query: 1755 TYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYI 1814
Y ++Y++ + N+++A IL++ + +T + ++W ++DP + +I
Sbjct: 1358 LYFVTYVIAMGYVFTNLFVASILDHVTFGVLREAAIITPKHLYDFQQVWSKYDPLATGFI 1417
Query: 1815 RYDQLSDFLDVLEPPLQI 1832
+L + L L PPL +
Sbjct: 1418 GAHRLGELLRDLSPPLAV 1435
Score = 86.6 bits (205), Expect = 6e-15
Identities = 68/250 (27%), Positives = 122/250 (48%), Gaps = 27/250 (10%)
Query: 176 IYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM-----GIDL----GNLAA 226
+Y+ E+A ++ + GFI Y+ +N +D +IA+++++M G D +
Sbjct: 50 VYSIEAAARIFSLGFIGHKHAYMSSVYNQVDLAIIAVSWLSMTMQWHGSDSLFTRVRVGQ 109
Query: 227 LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLT 286
LR FR + ALK + + I ++ +S+ LRDV +T+ +ALMG+ I+ G L
Sbjct: 110 LRFFRGVHALKRFKLATSVVFIAESLQKSIVLLRDVAAITVICAVFYALMGMGIFGGSLR 169
Query: 287 QKCVK-VFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQG 345
++CV+ E + FC + N G Y +C G C
Sbjct: 170 RRCVETTSAETARMFYTAVSDPPLFCGDVGNLPNHKG-Y-VC---PGVYDSNSSLFCSDL 224
Query: 346 FGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWEN-LYQL----------FFVVIIFLGSFY 394
G NP +GY SFD+FG L F+ +T + W++ +Y + +FV +I +G+++
Sbjct: 225 VG-NPQHGYQSFDSFGSTLLVMFQTITIEAWQDVMYPIVNAEYKASAAYFVTLIIVGTYF 283
Query: 395 LVNLILAIVA 404
+V++ +A V+
Sbjct: 284 IVSVFVAAVS 293
Score = 60.9 bits (141), Expect = 3e-07
Identities = 68/281 (24%), Positives = 125/281 (44%), Gaps = 32/281 (11%)
Query: 1506 MKKMGSKKPLKAIPRPRWRPQAI-VFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETF 1564
M + G +AIP RP+ + E + FD ++ + I N+ M L + +T
Sbjct: 355 MLEEGDNDQTRAIPSGVARPKRDRLSERINHPYFDKMVRILIAANIAVMALYRFDLDDTK 414
Query: 1565 SAVLDYLNMIFIVIFSSECLLKIFAL----RYHYFVEPWNLFDFVVVMFSILSLVLSDII 1620
L F+ F E +L+ A R +P N D ++V + + + + ++
Sbjct: 415 KEYLVIAEGFFVSAFMLEVILRGLAAKDIGRRIVTFKPTNE-DLMLVFDTGVVAISATVM 473
Query: 1621 EKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFA 1680
++ T LR+ R+ K K G+ T+ + SL +L ++ L ++ ++A
Sbjct: 474 WGKGMNLTSLRIPRLFKT---FGPAKSQTGVDTIN-RVFKSLGSLLSLFLFYVAILAMYA 529
Query: 1681 IFGMSFFMHVKDKGGLDDV--YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPD 1738
+ GM F + +D GL+D+ ++ TF Q+M+ LF ST GW ++ + +P
Sbjct: 530 VLGMQLFAN-RD-AGLEDMPRLHYNTFPQAMLALFVASTGEGWTDLMFHGVQITNAAIP- 586
Query: 1739 NERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILEN 1779
+ +S+ V+ IV+N+ IAV+LEN
Sbjct: 587 -----------------FYISFFVLVNYIVLNLVIAVVLEN 610
Score = 50.0 bits (114), Expect = 6e-04
Identities = 40/169 (23%), Positives = 77/169 (45%), Gaps = 12/169 (7%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVEST--------EVIFTGIY 177
P +RRV +I+ H + F++ + +N LM ES E+ F G+Y
Sbjct: 1130 PPRGLRRVCFHIVNHRSYRAFVLIGVGLNAALMATERYGDGESVLAHVRSIGEICFVGVY 1189
Query: 178 TFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAAL--RTFRVLRA 235
E ++V A ++ Y + WN + + + VT+ G+L R FR LR
Sbjct: 1190 LIEVLLQVSAAYPSVR--HYFSNKWNAFELTLAVGSAVTLQSKAGSLRDQIGRPFRFLRV 1247
Query: 236 LKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
+ + V L+ + ++ ++ ++ V+ L + + ++A +G QI+ V
Sbjct: 1248 FRIIRHVQSLQILASTLLLAIPSILSVMGLMLIWMFMYAGIGTQIFPNV 1296
Score = 43.2 bits (97), Expect = 0.074
Identities = 27/99 (27%), Positives = 56/99 (56%), Gaps = 7/99 (7%)
Query: 832 YLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDR 891
+LRVF++ + +L +L S + + ++ ++ ++ I +F++A +G Q+F +
Sbjct: 1244 FLRVFRIIRHVQSLQILASTLLLAIPSILSVMGLMLIWMFMYAGIGTQIFPN------VK 1297
Query: 892 FPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCML 929
F + NF F SF+++F+V+ GE W + M+D M+
Sbjct: 1298 FGEALNKDANFQTFTSSFLLLFQVITGEGWRQYMYDLMV 1336
Score = 39.5 bits (88), Expect = 0.91
Identities = 29/121 (23%), Positives = 61/121 (50%), Gaps = 9/121 (7%)
Query: 826 ALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY 885
+L+ + F AKS ++ + + +++G+L +L I+ ++AV+GMQLF
Sbjct: 482 SLRIPRLFKTFGPAKSQTGVDTINRVF-KSLGSLLSLFLFYVAILAMYAVLGMQLFANRD 540
Query: 886 VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSCIPFFLATVV 944
D+PR ++ F + + +F GE W + M+ + + + + IPF+++ V
Sbjct: 541 AGL------EDMPRLHYNTFPQAMLALFVASTGEGWTDLMFHGVQITN-AAIPFYISFFV 593
Query: 945 I 945
+
Sbjct: 594 L 594
Score = 36.7 bits (81), Expect = 6.4
Identities = 30/132 (22%), Positives = 62/132 (46%), Gaps = 8/132 (6%)
Query: 1255 MDRIFTVIFFIEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQ 1310
+D ++ IE + +LGF Y ++ + +D I+ VS ++ G+ +
Sbjct: 43 IDAAILCVYSIEAAARIFSLGFIGHKHAYMSSVYNQVDLAIIAVSWLSMTMQWHGSDSLF 102
Query: 1311 AFKTMRTLRALRPLRAMSRMQGMRVVV---NALVQAIPSIFNVLLVCLIFWLIFAIMGVQ 1367
+ LR R + A+ R + VV +L ++I + +V + +I + +A+MG+
Sbjct: 103 TRVRVGQLRFFRGVHALKRFKLATSVVFIAESLQKSIVLLRDVAAITVICAVFYALMGMG 162
Query: 1368 LFAGKY-FKCVD 1378
+F G +CV+
Sbjct: 163 IFGGSLRRRCVE 174
>UniRef50_Q4RXK3 Cluster: Chromosome 11 SCAF14979, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 11
SCAF14979, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 2055
Score = 197 bits (480), Expect = 3e-48
Identities = 131/402 (32%), Positives = 210/402 (52%), Gaps = 32/402 (7%)
Query: 1247 ILQDILYYMDRIFTVIFFIEMLIKWLALG--FQK--YFTNAWCWLDFIIVMVSLINFVAA 1302
I+ +L Y D +FT +F E+++K G K + N + LD ++V VSL++F
Sbjct: 677 IVLKVLGYADYVFTSMFTFEIILKMTTYGAFLHKGAFCRNYFNLLDLLVVGVSLVSFGIQ 736
Query: 1303 LCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFA 1362
+ I K +R LR LRPLRA++R +G++ VV + AI +I N+++V + +FA
Sbjct: 737 ---SSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFA 793
Query: 1363 IMGVQLFAGKYFKCVDMNHTTLSH----EII---PDKNACTLENYTWENSPMNFDHVGKA 1415
+GVQLF GK+++C D ++ I+ D N T+ W NS NFD+V A
Sbjct: 794 CIGVQLFKGKFYRCTDEAKSSPEECKGTYILYKDGDVNQPTIHKRVWHNSDFNFDNVLMA 853
Query: 1416 YLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGV 1475
+ LF V+TF+GW ++ AIDS PI + + ++ +N+F+G
Sbjct: 854 MMALFTVSTFEGWPALLYKAIDSNRENLGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGF 913
Query: 1476 IIDNFNEQKKKAGGSLEMFMTE-------DQKKYYNAMKKMGSKK------PLKAIPRPR 1522
+I F EQ +K + E+ + + +Y A G + LKA P R
Sbjct: 914 VIVTFQEQGEKEYKNCELDKNQVSVAAGLQKVEYCCAGSGCGRSQRQCVEYALKARPLRR 973
Query: 1523 WRP----QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVI 1578
+ P Q + +V F+ I+ + I LN L + + HY QS F+ V+D LNM+F +
Sbjct: 974 YIPKNPYQYKFWYVVNSTGFEYIMFVLIMLNTLCLAVQHYGQSALFNYVMDILNMVFTAV 1033
Query: 1579 FSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDI 1619
F+ E +LK+ A + YF + WN+FD +VV+ SI+ +VLS+I
Sbjct: 1034 FTVEMVLKLIAFKPRGYFGDAWNVFDALVVIGSIVDIVLSEI 1075
Score = 100 bits (239), Expect = 5e-19
Identities = 68/252 (26%), Positives = 129/252 (51%), Gaps = 24/252 (9%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFV 1596
F ++++ + LN LT++ +HY Q + V D N + + +F+ E L+K+++L YFV
Sbjct: 333 FYWLVIILVFLNTLTISSEHYNQPLWLTEVQDVANKVLLALFTCEMLMKMYSLGLEAYFV 392
Query: 1597 EPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLF 1656
+N FD VV I +L +E +SP + V R ++ R+ ++ + + + L+
Sbjct: 393 SLFNRFDCFVVCGGITETIL---VELEIMSPLGISVFRCVRLLRIFKVTRHWQSLSNLVA 449
Query: 1657 ALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVY----NFKTFVQSMILL 1712
+L S+ ++ ++ LLLFL + IF++ GM F K D+ F F Q+++ +
Sbjct: 450 SLLNSMKSIASLLLLLFLFIIIFSLLGMQVF---GGKFNFDETQTKRSTFDNFPQALLTV 506
Query: 1713 FQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINM 1771
FQ+ T W+ V+ DGI+ G P + G I Y + + I++N+
Sbjct: 507 FQILTGEDWNAVMYDGIM----------AYGGPSSSG--MIVCFYFIILFICGNYILLNV 554
Query: 1772 YIAVILENYSQA 1783
++A+ ++N + A
Sbjct: 555 FLAIAVDNLADA 566
Score = 77.4 bits (182), Expect = 4e-12
Identities = 58/194 (29%), Positives = 106/194 (54%), Gaps = 34/194 (17%)
Query: 223 NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYM 282
++ ALR FRVLR L+ V+ VP L+ ++ ++I+++ L + +L +F + ++A++GL++++
Sbjct: 43 DVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFI 102
Query: 283 GVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVC 342
G + C P GS ++ +E C G G P+ G +C G+
Sbjct: 103 GKMHATC--YIP--GS-DSIAEEE-PAPCAIS----GHGRQCPINGT-----ECREGW-- 145
Query: 343 LQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQD------YWEN------LYQLFFVVIIFL 390
QG PN G T+FD F +A L+ F+ +T + YW N L ++FV ++
Sbjct: 146 -QG----PNGGITNFDNFLFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIF 200
Query: 391 GSFYLVNLILAIVA 404
GSF+++NL+L +++
Sbjct: 201 GSFFVLNLVLGVLS 214
Score = 74.5 bits (175), Expect = 3e-11
Identities = 71/323 (21%), Positives = 137/323 (42%), Gaps = 41/323 (12%)
Query: 1174 DDTPADCCPEQCYQKFPFLAGDDDSPFWQGWGTL-RLKTFKLIENTYFETAVITMILLSS 1232
+D CC C QK ++ S W+ W R K +++ F VI ++ L++
Sbjct: 290 EDEKTTCCGPLC-QK---ISKSKFSRRWRRWNRFCRRKCRLAVKSVPFYWLVIILVFLNT 345
Query: 1233 LALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIV 1292
L ++ E + P L ++ +++ +F EML+K +LG + YF + + D +V
Sbjct: 346 LTISSEHYNQPLW--LTEVQDVANKVLLALFTCEMLMKMYSLGLEAYFVSLFNRFDCFVV 403
Query: 1293 MVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLL 1352
+ + R +R LR + Q + +V +L+ ++ SI ++LL
Sbjct: 404 CGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWQSLSNLVASLLNSMKSIASLLL 463
Query: 1353 VCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHV 1412
+ +F +IF+++G+Q+F GK+ + + T + FD+
Sbjct: 464 LLFLFIIIFSLLGMQVFGGKF----NFDET--------------------QTKRSTFDNF 499
Query: 1413 GKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLF 1472
+A L +FQ+ T + W +M D I + + + + Y LN+F
Sbjct: 500 PQALLTVFQILTGEDWNAVMYDGI----MAYGGPSSSGMIVCFYFIILFICGNYILLNVF 555
Query: 1473 IGVIIDN------FNEQKKKAGG 1489
+ + +DN N+ + K GG
Sbjct: 556 LAIAVDNLADAESLNKDEDKKGG 578
Score = 70.5 bits (165), Expect = 4e-10
Identities = 35/117 (29%), Positives = 67/117 (57%), Gaps = 3/117 (2%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA--- 226
+ +FT ++TFE +K+ G L + R+ +N LD +V+ ++ V+ GI ++
Sbjct: 686 DYVFTSMFTFEIILKMTTYGAFLHKGAFCRNYFNLLDLLVVGVSLVSFGIQSSAISVVKI 745
Query: 227 LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
LR RVLR L+ + GLK +V V +++ + +++I+T +FA +G+Q++ G
Sbjct: 746 LRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKG 802
Score = 66.1 bits (154), Expect = 9e-09
Identities = 54/198 (27%), Positives = 95/198 (47%), Gaps = 30/198 (15%)
Query: 1307 GGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGV 1366
GG K +R R LRPLR +S + ++VV+N++++A+ + ++ L+ L +I+AI+G+
Sbjct: 40 GGFDV-KALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 98
Query: 1367 QLFAGK-YFKCVDMNHTTLSHE------IIPDKNACTL------ENYTWENSPM-NFDHV 1412
+LF GK + C +++ E I C + E + N + NFD+
Sbjct: 99 ELFIGKMHATCYIPGSDSIAEEEPAPCAISGHGRQCPINGTECREGWQGPNGGITNFDNF 158
Query: 1413 GKAYLCLFQVATFKGWIQI---MNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTL 1469
A L +FQ T +GW + MNDA+ ++Y L
Sbjct: 159 LFAMLTVFQCITMEGWTDVLYWMNDAMGFE------------LPWVYFVSLVIFGSFFVL 206
Query: 1470 NLFIGVIIDNFNEQKKKA 1487
NL +GV+ F+++++KA
Sbjct: 207 NLVLGVLSGEFSKEREKA 224
Score = 60.1 bits (139), Expect = 6e-07
Identities = 30/95 (31%), Positives = 56/95 (58%), Gaps = 6/95 (6%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LR+FK+ + W +L+ L++ + +M ++ +L +L + I IF+++GMQ+FG + F
Sbjct: 432 LRIFKVTRHWQSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQVFGGKF-----NF 486
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWD 926
+ R F +F + + VF++L GE W M+D
Sbjct: 487 DETQTKRSTFDNFPQALLTVFQILTGEDWNAVMYD 521
Score = 54.0 bits (124), Expect = 4e-05
Identities = 25/91 (27%), Positives = 55/91 (60%), Gaps = 2/91 (2%)
Query: 1210 KTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLI 1269
K + ++ +T FE + +I+L++L LA++ H + ++ ++ +FT +F +EM++
Sbjct: 983 KFWYVVNSTGFEYIMFVLIMLNTLCLAVQ--HYGQSALFNYVMDILNMVFTAVFTVEMVL 1040
Query: 1270 KWLALGFQKYFTNAWCWLDFIIVMVSLINFV 1300
K +A + YF +AW D ++V+ S+++ V
Sbjct: 1041 KLIAFKPRGYFGDAWNVFDALVVIGSIVDIV 1071
Score = 50.0 bits (114), Expect = 6e-04
Identities = 35/126 (27%), Positives = 70/126 (55%), Gaps = 11/126 (8%)
Query: 1567 VLDYLNMIFIVIFSSECLLKI-----FALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIE 1621
VL Y + +F +F+ E +LK+ F + + +NL D +VV S++S I+
Sbjct: 681 VLGYADYVFTSMFTFEIILKMTTYGAFLHKGAFCRNYFNLLDLLVVGVSLVSFG----IQ 736
Query: 1622 KYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAI 1681
+S +++++RV +V R LR + AKG++ ++ + +++ + NI ++ L+ F+FA
Sbjct: 737 SSAIS--VVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFAC 794
Query: 1682 FGMSFF 1687
G+ F
Sbjct: 795 IGVQLF 800
Score = 41.5 bits (93), Expect = 0.23
Identities = 19/59 (32%), Positives = 36/59 (61%)
Query: 1630 LRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
++ +R +V R LRLV G ++ +L ++ ++ L +I LL+ V+ I+AI G+ F+
Sbjct: 44 VKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFI 102
Score = 39.1 bits (87), Expect = 1.2
Identities = 15/60 (25%), Positives = 35/60 (58%)
Query: 224 LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
++ R R+LR K L +V +++ S+K++ +++L + +F+L+G+Q++ G
Sbjct: 423 ISVFRCVRLLRIFKVTRHWQSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQVFGG 482
Score = 37.5 bits (83), Expect = 3.7
Identities = 16/57 (28%), Positives = 36/57 (63%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
KAL++ LR +L P+L ++++ + + M L ++ ++ +I I+A++G++LF
Sbjct: 45 KALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELF 101
>UniRef50_A0DXC4 Cluster: Chromosome undetermined scaffold_68, whole
genome shotgun sequence; n=4; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_68, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 2227
Score = 194 bits (473), Expect = 2e-47
Identities = 146/625 (23%), Positives = 296/625 (47%), Gaps = 29/625 (4%)
Query: 1212 FKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKW 1271
FK+ ++ Y + + +LLS LA+ + P+L +L+ ++ I + F I+ +
Sbjct: 1404 FKVSQSDYTKYFIDITLLLSITYLAIPS-DIQKDPLLVTLLFILNSIIFIEFIIKSIAYG 1462
Query: 1272 LALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQ 1331
L Y W +D +++ + F G + F+ + T RPL+ + R++
Sbjct: 1463 AFLDKGSYLNYTWKIIDLAYIVIYYVQFFKI----GYLPIFEVIETFLFFRPLKLLYRIR 1518
Query: 1332 GMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPD 1391
+ V AL Q++ I NV +V L+ WL+FA+ + L+A K C + + + E
Sbjct: 1519 WVARVRAALTQSLFDIINVFVVLLLVWLMFAVFSMMLYADKLGYCEEQFNYDIGIE---- 1574
Query: 1392 KNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREV--GRQPIRET 1449
C N +W NFD++ A LF ++TF GW I+ + +SRE G P +
Sbjct: 1575 --ECKQLNKSWIVYKHNFDNITTAMPSLFVISTFDGWGAILWASQNSRESYSGPHPYY-S 1631
Query: 1450 NIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKM 1509
Y++ L LF GV+ N K+ +T+ Q ++ N + +
Sbjct: 1632 QAPTYVFYIAFCTIGSMFFLQLFTGVLFINLKANSKQIENQQ---LTQAQLEFKNVTEII 1688
Query: 1510 GSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLD 1569
P+++ P+ + ++ I+T + D + + +N +T+ + ++ ++ +++
Sbjct: 1689 LFDHPVRS-SLPKSYIRKVLATIITSQFMDFFMFSILLINCVTIMMIYHSADFDYNRIIN 1747
Query: 1570 YLNMIFIVIFSSECLLKIFALRYHYFVE-PWNLFDFVVVMFSILSLVLSDIIEKYFVSPT 1628
+N +IF+ LL+ AL + F + PW L+ VV++ ++ LVL +
Sbjct: 1748 LINHACTIIFAIWVLLQGIALGINRFKDNPWRLYTTVVIILGVVDLVLYVYSTQLTPHYQ 1807
Query: 1629 LLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
LLRV+ + + RV+ + +G + ++ L+ ++ + P LF I +L ++M +FA +G F
Sbjct: 1808 LLRVMYMLRNLRVIIIFQGLQKLQRLVRVISFAFPFLFKILFILLIIMVVFAFYGTMLFG 1867
Query: 1689 HVKDKGG-LDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNC 1747
H+ DKG ++D+ NFK F +++ LF+ + + +++ ++ D P C
Sbjct: 1868 HI-DKGEVINDLINFKNFWLAILTLFKCVSGDDFRSIMNDCMHHNPYCQED-----PKYC 1921
Query: 1748 GSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTD--DDYDMYYEIWQR 1805
GS I Y + +++IS +++N+++ ++E + + L ++ D + + W +
Sbjct: 1922 GSPYSQI-YFIIFMLISNYVLLNLFVLAMIEQFELFFNNQDSILQTYVENIDTFRKAWFK 1980
Query: 1806 FDPDGSQYIRYDQLSDFLDVLEPPL 1830
F + Q++ L L ++ PL
Sbjct: 1981 FSCNHGQFLNIKNLPFLLMEIKEPL 2005
Score = 57.2 bits (132), Expect = 4e-06
Identities = 48/224 (21%), Positives = 104/224 (46%), Gaps = 14/224 (6%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
K+I + ++T + L ++ L + + HL H L+ ++ F ++ ++++++
Sbjct: 340 KIIVRSRIYQYLLTFVTLGNIILFIYE-HLNHD---NQNLFAINFGFLWLYVVDIVLQLF 395
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG 1332
A G F + + +L +I ++ F L + +R +R L+ L A+ +G
Sbjct: 396 AFGL---FRSKFIFLGRVIDAFLIVMFYYHLAYTETVVNITPLRMMRLLKQLGAI--FEG 450
Query: 1333 MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYF-KCVDMNHTTLSHEI--- 1388
++ ++ AL++++ IF V ++F L FA +G LF + +C+ I
Sbjct: 451 LQRMIEALIESLKFIFESTAVVILFVLFFASLGNSLFMSLFNERCLPSEEDEWIQCIQGE 510
Query: 1389 IPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIM 1432
PD C + N + N P NF+++ ++ + + T W +M
Sbjct: 511 CPDGKTCVMTNKAF-NIPTNFNNIIYSFGLMLKTVTMDDWSWVM 553
Score = 47.2 bits (107), Expect = 0.005
Identities = 52/233 (22%), Positives = 101/233 (43%), Gaps = 31/233 (13%)
Query: 173 FTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID--LGNLAALRTF 230
F +Y + +++ A G F +L +D +I + Y + + N+ LR
Sbjct: 382 FLWLYVVDIVLQLFAFGLFRSKFIFLGRV---IDAFLIVMFYYHLAYTETVVNITPLRMM 438
Query: 231 RVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCV 290
R+L+ L AI GL+ ++ A+IES+K + + + + + FA +G ++M + ++C+
Sbjct: 439 RLLKQLG--AIFEGLQRMIEALIESLKFIFESTAVVILFVLFFASLGNSLFMSLFNERCL 496
Query: 291 KVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGY-VCLQGFGPN 349
P + ++ W + Q GE D C ++ A + + FG
Sbjct: 497 ---PSE-------EDEWIQCIQ------GECPDGKTCVMTNKAFNIPTNFNNIIYSFG-- 538
Query: 350 PNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQLFFVVIIFLGSFYLVNLILAI 402
+ D + W R W +++V+IIF+G F+ NL +A+
Sbjct: 539 LMLKTVTMDDWSWVMYYTIRAFHPIVW-----IYYVLIIFVGGFFGFNLPIAV 586
Score = 46.0 bits (104), Expect = 0.011
Identities = 36/167 (21%), Positives = 72/167 (43%), Gaps = 8/167 (4%)
Query: 122 WILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTT----PTVESTEVIFTGIY 177
+I N R++ + FI T+L++ + +P+ P + + I I
Sbjct: 1391 YIFHKSNNFRKLLFKVSQSDYTKYFIDITLLLSITYLAIPSDIQKDPLLVTLLFILNSII 1450
Query: 178 TFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNL---AALRTFRVLR 234
E +K +A G L +YL W +D I + YV +G L + TF R
Sbjct: 1451 FIEFIIKSIAYGAFLDKGSYLNYTWKIIDLAYIVIYYVQF-FKIGYLPIFEVIETFLFFR 1509
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
LK + + + + A+ +S+ ++ +V ++ + +FA+ + +Y
Sbjct: 1510 PLKLLYRIRWVARVRAALTQSLFDIINVFVVLLLVWLMFAVFSMMLY 1556
Score = 42.3 bits (95), Expect = 0.13
Identities = 41/169 (24%), Positives = 84/169 (49%), Gaps = 10/169 (5%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
LR F++I + IL+++L LAL+ I ++I+ + I TV+ E
Sbjct: 975 LRKYAFQIIHFKLTKFLFDLTILINTLFLALQGT------INRNIIDNEEDIATVLLSTE 1028
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
++++ + ++ N ++ +IV++SLI F + Q + MR+ + L R
Sbjct: 1029 IILQLIVYQPKRIAKNKHHVIELLIVILSLIEFGFSSYLNVSEQYLRLMRSTKCLLFYRC 1088
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLI--FAIMGVQLFAGKY 1373
+ +Q R++ + +I + L L+F++I F ++G++LFA K+
Sbjct: 1089 ILYIQMARII--GAIASITYKSYIYLTFLMFFMILTFGLIGMELFANKF 1135
Score = 39.1 bits (87), Expect = 1.2
Identities = 41/196 (20%), Positives = 83/196 (42%), Gaps = 7/196 (3%)
Query: 1530 FEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFA 1589
F+I+ K + L I +N L + L Q ++D I V+ S+E +L++
Sbjct: 980 FQIIHFKLTKFLFDLTILINTLFLAL----QGTINRNIIDNEEDIATVLLSTEIILQLIV 1035
Query: 1590 LRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
+ + N + ++ ILSL+ VS LR++R K R + +
Sbjct: 1036 YQPKRIAK--NKHHVIELLIVILSLIEFGFSSYLNVSEQYLRLMRSTKCLLFYRCILYIQ 1093
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDK-GGLDDVYNFKTFVQS 1708
R + +++ + + L+F ++ F + GM F + D+ + +F ++
Sbjct: 1094 MARIIGAIASITYKSYIYLTFLMFFMILTFGLIGMELFANKFDEYHNKGYMQSFDDPAKA 1153
Query: 1709 MILLFQMSTSAGWDGV 1724
+ +F + T+ W GV
Sbjct: 1154 FMTVFNIMTNDDWFGV 1169
Score = 37.5 bits (83), Expect = 3.7
Identities = 36/168 (21%), Positives = 73/168 (43%), Gaps = 12/168 (7%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCI-LMIMPTTPTVESTEVI--FTGIYTFESA 182
P + IR+V I+ F+ + +L+NC+ +M++ + + +I T A
Sbjct: 1699 PKSYIRKVLATIITSQFMDFFMFSILLINCVTIMMIYHSADFDYNRIINLINHACTIIFA 1758
Query: 183 VKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDL------GNLAALRTFRVLRAL 236
+ V+ +G L + + W VVI L V + + + + LR +LR L
Sbjct: 1759 IWVLLQGIALGINRFKDNPWRLYTTVVIILGVVDLVLYVYSTQLTPHYQLLRVMYMLRNL 1818
Query: 237 KTVAIVPG---LKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+ + I G L+ +V + + L ++ + + + VFA G ++
Sbjct: 1819 RVIIIFQGLQKLQRLVRVISFAFPFLFKILFILLIIMVVFAFYGTMLF 1866
Score = 37.1 bits (82), Expect = 4.9
Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 7/97 (7%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LRV + + L L+ ++ L + F+L II+ +FA G LFG ++D +
Sbjct: 1818 LRVIIIFQGLQKLQRLVRVISFAFPFLFKILFILLIIMVVFAFYGTMLFG--HIDKGEVI 1875
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGEWIES-MWDCM 928
D NF +F + + +F+ + G+ S M DCM
Sbjct: 1876 ND----LINFKNFWLAILTLFKCVSGDDFRSIMNDCM 1908
>UniRef50_Q6C5T4 Cluster: Similar to sp|P50077 Saccharomyces
cerevisiae YGR217w CCH1 calcium channel protein; n=1;
Yarrowia lipolytica|Rep: Similar to sp|P50077
Saccharomyces cerevisiae YGR217w CCH1 calcium channel
protein - Yarrowia lipolytica (Candida lipolytica)
Length = 2074
Score = 193 bits (470), Expect = 5e-47
Identities = 143/594 (24%), Positives = 285/594 (47%), Gaps = 36/594 (6%)
Query: 1254 YMDRIFTVIFFIEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGI 1309
+ D F ++F IE +IK LA GF Y ++W +DFI+++ IN +A G G +
Sbjct: 1179 WSDLGFLILFSIEAIIKILADGFYFTPNAYLRSSWGVIDFIVLISLWINMIAIFAGNGYV 1238
Query: 1310 QAFKTMRTLRALRPLRAMSRMQGMRVVV-NALVQAIPSIFNVLLVCLIFWLIFAIMGVQL 1368
+ +R +ALR LR ++ + N ++ I IF ++ + F++ G+Q+
Sbjct: 1239 S--RAVRAFKALRALRLLNISNAAKETFENIVIVGIRKIFGAAMISMCLLYPFSVWGLQI 1296
Query: 1369 FAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPM----NFDHVGKAYLCLFQVAT 1424
F G+++ C D N L++ I ++ + N S + +FD+ G ++L LF++ +
Sbjct: 1297 FKGRFYSCNDENTEFLANCINEFASSPSNWNVLAPRSVVKPYYDFDNFGHSFLILFEIIS 1356
Query: 1425 FKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQK 1484
+GW ++ + + G ++ + L LFI VII N++
Sbjct: 1357 LEGWTDVLKTTMSIQGPGMNLEWAASVNNSAFLVLYNFISTVFILTLFIAVIIKNYSRTT 1416
Query: 1485 KKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKA---IPRPRWRPQAIVFEIVTDKK--FD 1539
A F+T++Q+ + A K + KP + WR + +VT++K ++
Sbjct: 1417 GTA------FLTQEQRAWAEAEKILKLVKPSIVPVYVREGTWREYC--YRVVTNRKGKWN 1468
Query: 1540 MIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVE-P 1598
+ + ++++ + L+ Y Q + + L + ++I +++ +A Y F+
Sbjct: 1469 KFLAGLLFIHLIILCLEWYPQYLYAEDIRNGLFLPILIILDLNEIMRFYAFGYKGFMSRK 1528
Query: 1599 WNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFAL 1658
W+L+ +VV ++++ + S FVS T ++ +VG +L + ++ + L
Sbjct: 1529 WDLYTVLVVTGALVTTIFSFAS---FVSNTYYNFQKLCQVGILLLFIPRSERLDQLFKTT 1585
Query: 1659 AMSLPALFNICLLLFLVMFIFAI-FGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMST 1717
+ S ++ N+ ++ ++AI F F + G ++ NF+T +++ILLF+MS
Sbjct: 1586 SASFASILNLMATWIVLFVVYAIAFNQIFGLTRVGPNGTGNI-NFRTVPKALILLFRMSC 1644
Query: 1718 SAGWDGVLDGIINEEECDLPDNERG-SPGNCGSATIGITYLLSYLVISFLIVINMYIAVI 1776
GW+ ++ + E + N G + +CGS +S+ ++S I +NM++++I
Sbjct: 1645 GEGWNQIMSDYLLEPPYCI--NGAGFNETDCGSRPYAYLLFISWNILSMYIFVNMFVSLI 1702
Query: 1777 LENYS---QATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLE 1827
EN+S Q T + + ++ Y + W+ FDP G+ YIR D+L FL +E
Sbjct: 1703 YENFSYVYQQTGPLSRAIKREELRKYKKAWREFDPTGTGYIRPDELHRFLRRIE 1756
Score = 66.5 bits (155), Expect = 7e-09
Identities = 38/116 (32%), Positives = 64/116 (55%), Gaps = 5/116 (4%)
Query: 173 FTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM-GIDLGN---LAALR 228
F +++ E+ +K++A GF P YLR +W +DF+V+ ++ M I GN A+R
Sbjct: 1184 FLILFSIEAIIKILADGFYFTPNAYLRSSWGVIDFIVLISLWINMIAIFAGNGYVSRAVR 1243
Query: 229 TFRVLRALKTVAIVPGLK-TIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
F+ LRAL+ + I K T VI ++ + +++M L F++ GLQI+ G
Sbjct: 1244 AFKALRALRLLNISNAAKETFENIVIVGIRKIFGAAMISMCLLYPFSVWGLQIFKG 1299
Score = 57.2 bits (132), Expect = 4e-06
Identities = 56/233 (24%), Positives = 105/233 (45%), Gaps = 28/233 (12%)
Query: 197 YLRDAWNWLDFVVIALAYVTMGI---DLGNLAALRTFR---VLRALKTVAIVPGLKTIVG 250
+LR +WN +DF+ + ++++G+ D + L FR LR L+ + + G ++
Sbjct: 436 FLRSSWNRVDFISVVCYWISLGVAAHDYDIIHQLFLFRFLACLRILRLLNLTHGTTAVLR 495
Query: 251 AVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERF 310
A+ S L +V + F F+++G Q + L ++CV V S G + +E++
Sbjct: 496 ALKTSAPLLINVSLFIGFFWVTFSIIGTQSFKASLRRQCVWV----DSTGQQDNYTYEQY 551
Query: 311 CQNETNWYGEGGDY-PLCGNSSGAGQCEPGYVCLQG----FGPNPNYGYTSFDTFGWAFL 365
C + E ++ P G GY+C G NP G SFD +
Sbjct: 552 CGGYL--HPETLEHMPYVFTDGTVGPQSKGYMCPAGSICVSDKNPYGGTVSFDNIFNSLE 609
Query: 366 SAFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
F +++ + + ++ LFF+ I + + +L NL++A++A SY
Sbjct: 610 MVFVIISLNTFTDIMYYTMDSDYMTACLFFMAGILILALWLANLLVAVIATSY 662
Score = 48.4 bits (110), Expect = 0.002
Identities = 33/105 (31%), Positives = 50/105 (47%), Gaps = 1/105 (0%)
Query: 1279 YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVN 1338
+ ++W +DFI V+ I+ A I R L LR LR ++ G V+
Sbjct: 436 FLRSSWNRVDFISVVCYWISLGVAAHDYDIIHQLFLFRFLACLRILRLLNLTHGTTAVLR 495
Query: 1339 ALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF-AGKYFKCVDMNHT 1382
AL + P + NV L FW+ F+I+G Q F A +CV ++ T
Sbjct: 496 ALKTSAPLLINVSLFIGFFWVTFSIIGTQSFKASLRRQCVWVDST 540
Score = 44.0 bits (99), Expect = 0.042
Identities = 48/248 (19%), Positives = 106/248 (42%), Gaps = 21/248 (8%)
Query: 1542 IMLFIGLNML-TMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWN 1600
+++F+ L + T T D ET L L +I + +++ +L+ + ++ + N
Sbjct: 712 LIIFMSLVVSSTRTADTTDSQET---ALYILEIIITSMLTADVILRFYVYLPNWRIFFLN 768
Query: 1601 LFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAM 1660
+ + V ++ +V+ +I P L + + ++ R+ R+V K R L +
Sbjct: 769 IANVVDCALGVMCIVI--LIPPIHNKPVLYGWLTIFQILRIYRVVMFFKFTRLLWRRVVG 826
Query: 1661 SLPALFNICLLLFLVMFIFAIFGMSFFMHV---KDKGGLDDVYNFKTFVQSMILLFQMST 1717
+ +F + FL+ F+ ++ V +D G ++F + + ++ +ST
Sbjct: 827 NYRTMFYMSCFFFLLTFLCSVMSTRLLRGVIPQEDDSGESIEFSFYNLQNTFLGMYALST 886
Query: 1718 SAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVIL 1777
+ W D+ N + N SA + + + + S +V+N++IA+I
Sbjct: 887 TENWT------------DMLYNGQQFATNTFSALCIAAFFIGWFIFSNNVVMNLFIALIT 934
Query: 1778 ENYSQATE 1785
EN + E
Sbjct: 935 ENLDVSEE 942
Score = 36.3 bits (80), Expect = 8.5
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 3/89 (3%)
Query: 1599 WNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFAL 1658
WN DF+ V+ +SL ++ Y + L + R R+LRL+ G +L AL
Sbjct: 441 WNRVDFISVVCYWISLGVA--AHDYDIIHQLF-LFRFLACLRILRLLNLTHGTTAVLRAL 497
Query: 1659 AMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
S P L N+ L + F+I G F
Sbjct: 498 KTSAPLLINVSLFIGFFWVTFSIIGTQSF 526
>UniRef50_A0D436 Cluster: Chromosome undetermined scaffold_37, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_37, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 1568
Score = 189 bits (461), Expect = 6e-46
Identities = 128/624 (20%), Positives = 296/624 (47%), Gaps = 23/624 (3%)
Query: 1210 KTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLI 1269
K +++++ F+ + ++L S++ + L+ L IL + + T++F I++++
Sbjct: 812 KIRQIVDSFIFQLFCLLVVLASTIRIGLQTPFLDPNSSTSQILQIVKIVATILFIIQIIL 871
Query: 1270 KWLALGF---QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGI-QAFKTMRTLRALRPLR 1325
+A GF +K + + + + V+V+L+ ++ + + F ++R + +R
Sbjct: 872 NVIARGFILGEKSYIQRSPY-NALNVLVTLVEIISLFLPSHTVFNFFSSLRIIEFIRIGA 930
Query: 1326 AMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLS 1385
+S Q + + ALV+A ++ + + C I LI+ +L G+ + C ++ +
Sbjct: 931 FLS--QSINYISQALVKAFQTMLQLSIFCFIILLIYGTFATKLLKGQMYYCSSLSEEETN 988
Query: 1386 HEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQP 1445
I DK C +W N + +D++ + L LF AT + W++++ +R V P
Sbjct: 989 E--INDKWDCMDYGGSWVNRILGYDNIFDSALTLFITATTEAWLELLVHTWSARGVNLTP 1046
Query: 1446 IRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNA 1505
+ N + +Y LN+FI ++++ + + K KA G E + +Q+++
Sbjct: 1047 VNNHNRWWAVYYQVFFFIGNICMLNMFISLVVETYQQTKIKAQGMSE--LNSNQREWLQI 1104
Query: 1506 MKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFS 1565
+ + KP + +P+ + +F I + I LN T+ L + +Q + FS
Sbjct: 1105 KESINHLKPRRLYAKPKTKLGLFIFSIAESRITKYFWHALILLNTFTLALYYNRQDKQFS 1164
Query: 1566 AVLDYLNMIFIVIFSSECLLKIFALRYHYF-VEPWNLFDFVVVMFSILS-LVLSDIIEKY 1623
LDY+N+I + F+ E L ++ A + +P+ + D + ++ ++++ +S + +++
Sbjct: 1165 DALDYINLICTLAFTVEVLSRVIAKFPNILDRDPFIIVDVIGIIINLVNQFKISQLNDEF 1224
Query: 1624 FVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFG 1683
++ + ++ R ++K + L + + +P+ ++ ++F+ +FIFA G
Sbjct: 1225 YLQRGFEALSVGFQLLRNYYIIKRFPELEKLFYTIFSVVPSALSMLFIMFIFLFIFACLG 1284
Query: 1684 MSFFMHVKDKGGLDDV-YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDL------ 1736
M F +++ + ++ +FK F +M L ++++S W +L ++ D
Sbjct: 1285 MDLFGYLRPQQKMEGFDLHFKKFTTAMFSLIRVASSEEWWALLIDSVHVRTPDFACIYIN 1344
Query: 1737 --PDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDD 1794
+ + CG+ + Y+ +L+ S L+++N++IA IL Y + + Q ++
Sbjct: 1345 GYEEFQEYGYNGCGTYWAYVFYVSFHLIFS-LVILNLFIASILGAYEEHAKQEQSAISKY 1403
Query: 1795 DYDMYYEIWQRFDPDGSQYIRYDQ 1818
W ++DPDG+ ++ Y Q
Sbjct: 1404 QLHDVLNYWAQYDPDGTGFLNYKQ 1427
Score = 90.2 bits (214), Expect = 5e-16
Identities = 77/318 (24%), Positives = 143/318 (44%), Gaps = 13/318 (4%)
Query: 98 HNQTTFVVISKGKDIFRFSATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCIL 157
H+ T + K + + + + L+I NPIRR I ++ + ++ FI T I C++
Sbjct: 52 HDLITIKSLEKSQKDQKKAQNSTLFIFSNKNPIRRGIIKLIRNQNYTYFI-TLIAAICLV 110
Query: 158 MIMPTTPTVE-STEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVT 216
+ S EV+ I+ F+ + ++A G IL +YLRD WN + + +
Sbjct: 111 PYCINEKRLAISIEVVCNIIFGFDILLFIIAYGVILDKKSYLRDCWNIANVLAFIFTWFI 170
Query: 217 MGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALM 276
D ++T R+LR + + +P L+ A + S L+ V+I + FA++
Sbjct: 171 FLEDNKVNDVIKTIRLLRLFRLIQEIPLLRIQFTAYVSSFLKLKQVLIPIFLVMIYFAII 230
Query: 277 GLQIYMGVLTQKC-VKVFPEDGSWGNLTDENWERFCQ----NETNWYGEGGDYPLCGN-- 329
GL +++G+ ++C + P DG W L D+ + C E + G DY L N
Sbjct: 231 GLHLFIGLTERRCRITPEPVDGVW--LADDGVLKLCGIWDCPENLYCGSPEDYGLPKNVT 288
Query: 330 SSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQLFFVVIIF 389
+ + ++ F + +T + GW+ + + + +F+V+I
Sbjct: 289 ENNVAEFSWDFIRFDDFFHSLLVVFTFLNVTGWS--GTTFMFWKAMTTYVTATYFLVLIV 346
Query: 390 LGSFYLVNLILAIVAMSY 407
L +F L NL+LA+ S+
Sbjct: 347 LLAFILSNLLLALFYESF 364
Score = 39.9 bits (89), Expect = 0.69
Identities = 41/157 (26%), Positives = 70/157 (44%), Gaps = 10/157 (6%)
Query: 786 KYVALLVFDPFVELFITLCIV--VNTLFMAL--DHHNMDKDMDKALKSGNYLRVFKLAKS 841
K+ +L DPF+ + + I+ VN ++ D + + + LR + + K
Sbjct: 1189 KFPNILDRDPFIIVDVIGIIINLVNQFKISQLNDEFYLQRGFEALSVGFQLLRNYYIIKR 1248
Query: 842 WPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWN 901
+P L L + + + ++ F++ I +FIFA +GM LFG Y+ + DL
Sbjct: 1249 FPELEKLFYTIFSVVPSALSMLFIMFIFLFIFACLGMDLFG--YLRPQQKMEGFDLHFKK 1306
Query: 902 FTDFMHSFMIVFRVLCGEWIESMWDCMLV--GDVSCI 936
FT M S + V EW + D + V D +CI
Sbjct: 1307 FTTAMFSLIRV--ASSEEWWALLIDSVHVRTPDFACI 1341
Score = 37.1 bits (82), Expect = 4.9
Identities = 32/131 (24%), Positives = 64/131 (48%), Gaps = 8/131 (6%)
Query: 162 TTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYL-RDAWNWLDFVVIALAYVTMGID 220
T+ ++ +++ T ++ + + V+ARGFIL +Y+ R +N L+ V++ L + + +
Sbjct: 850 TSQILQIVKIVATILFIIQIILNVIARGFILGEKSYIQRSPYNALN-VLVTLVEI-ISLF 907
Query: 221 LGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
L + F LR ++ + I L + + +++ TM LS+F + L I
Sbjct: 908 LPSHTVFNFFSSLRIIEFIRIGAFLSQSINYISQALVK----AFQTMLQLSIFCFIILLI 963
Query: 281 YMGVLTQKCVK 291
Y G K +K
Sbjct: 964 Y-GTFATKLLK 973
Score = 36.3 bits (80), Expect = 8.5
Identities = 36/153 (23%), Positives = 67/153 (43%), Gaps = 10/153 (6%)
Query: 1228 ILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWL 1287
I+LS LA+ ++ + + Q L +D + FIEM I G + YF+
Sbjct: 460 IILSGLAIIIDYKDISKTALEQ--LQIVDFFCIIYSFIEMAILITGRGLKGYFSKDINKF 517
Query: 1288 DFIIVMVS-LINFVAALCGAGGI-------QAFKTMRTLRALRPLRAMSRMQGMRVVVNA 1339
DF+I+ ++ FV + I FK+++ LR R + + +++ +
Sbjct: 518 DFLIISTQWILVFVLVVIDEPLIINHTVYVTFFKSLKILRVFRFVYNAKLFYTITLLMRS 577
Query: 1340 LVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGK 1372
LV + + N+L + ++ AI+G L K
Sbjct: 578 LVFTLTRLKNILALWACLVILIAIVGKSLLQNK 610
>UniRef50_A0BKL8 Cluster: Chromosome undetermined scaffold_112, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_112, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 1704
Score = 188 bits (458), Expect = 1e-45
Identities = 156/692 (22%), Positives = 331/692 (47%), Gaps = 46/692 (6%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALAL-EDVHLPHRPILQDILYYMDRIFTVIFFI- 1265
R+ L+ N YF +ILL+ + +AL + P+ I + IF +F+I
Sbjct: 917 RMLVTSLVTNIYFRIFNFALILLTCIRIALLSPLEDPNSDI--SFTLQVGYIFLTVFYIL 974
Query: 1266 EMLIKWLALGF----QKYFTNA-WCWLDFIIVMVSLINFVAALCGAGGIQAFKT-MRTLR 1319
+L+ +A G Q +F + + F+I +V LI + + + + F T +R L+
Sbjct: 975 VILLNCIAFGLYKNEQSFFRQSIYNIFSFVITIVDLITLIFDI--SHPLSKFVTSLRILQ 1032
Query: 1320 ALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDM 1379
++ S+ + +L+ A + + + CLI I+ ++ ++L G ++ C D
Sbjct: 1033 FIQIGAVFSK--NIAYAQASLLNAFTQMIQLTIFCLILLAIYGVLALKLLKGTFYYC-DA 1089
Query: 1380 NHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSR 1439
+ ++ + I K C +W N + FD + ++ L LF AT + WI ++ A ++
Sbjct: 1090 -YDSIHKDFIIKKEDCFDYGGSWVNQILTFDTIFQSILTLFCTATSENWIPLIQQAWNAV 1148
Query: 1440 EVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQ 1499
+V QPI+ N LY LN+FIG+I++ + E K KA + E Q
Sbjct: 1149 DVDHQPIQNYNRIYALYFQLFFFLGNLCLLNMFIGLIVNAYQEAKTKAQNF--HLLDETQ 1206
Query: 1500 KKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDM--IIMLFIGLNMLTMTLDH 1557
++++ ++ + +PL +P + I+F++V K F + +I++F +L+M
Sbjct: 1207 REWFQIKMQIYNMQPLVKSKKPSNYIRKILFQLVKQKYFKIFWLIIIFCNTIVLSMYFHR 1266
Query: 1558 YQQS--ETFSAVLDYLNMIFIVIFSSECLLKIFAL-RYHYFVEPWNLFDFVVVMFSILSL 1614
QS + ++ +LD +N +F+ IF+ E + + A + YF + N+ D + + ++I +L
Sbjct: 1267 SDQSVGDDYNQILDSINSVFVFIFAFEIVCRFLAKDKSLYFKDNSNIMDSIGIWWAIANL 1326
Query: 1615 VLSDIIEKYFVSPTLLRVVRVA-KVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLF 1673
+ + + F + + VA ++ R R++K + L ++ +P ++ ++F
Sbjct: 1327 FIRNHEDYNFHFRRISNAISVAFQLQRNFRIIKRFNNLEKLFSSIFSVIPNSLSMLFIMF 1386
Query: 1674 LVMFIFAIFGMSFFMHVKDKGGLDD-VYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEE 1732
+ +FI+ G+ F ++ + L+ +F+ F +M L ++++S W ++ ++E+
Sbjct: 1387 IFLFIYTTLGIDMFAFIRTQSNLNGWDQHFRKFSTAMFSLIKVASSESWWFIMVDTLHEQ 1446
Query: 1733 E----CD----LPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQAT 1784
+ C+ D ++ CG+ Y +S+ +I L+++N+ IA +L Y +
Sbjct: 1447 QPNFACNYMSTYADYQKYGFNGCGT-PYAYLYFVSFHLIFSLMILNLLIASVLGAYEEHV 1505
Query: 1785 EDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYD---QLSDFLDVL-----EPPLQI-HKP 1835
+ + ++ + +W+ +DP+G I Y +LS + ++ + L + +K
Sbjct: 1506 KSEESAVSKYQLNDVLSLWRNYDPEGKGLINYKDFWKLSSEIAIIFGVAQDDLLDVNNKK 1565
Query: 1836 NKYKIISMDIPICRGDMMFCV---DILDALTK 1864
N K++++ I + M C D++ +LTK
Sbjct: 1566 NFLKVLNIPIYESKESNMLCYQFHDVILSLTK 1597
Score = 69.3 bits (162), Expect = 1e-09
Identities = 56/243 (23%), Positives = 108/243 (44%), Gaps = 25/243 (10%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRT 229
E+ I+ E ++ +GF+L YL+ WN ++F+ + +G +
Sbjct: 150 EIFCNIIFGLECLGSIIIKGFVLGKNAYLKSWWNVVNFLTFIATWSILGDIKSENQLVHI 209
Query: 230 FRVLRALKTVAIVPG---LKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLT 286
RV+R +T+ ++ LK A I S L ++I +F + ++++GL ++MG+
Sbjct: 210 LRVIRLFRTLRLIQDSKILKKQFDAFIGSFSRLGPILIPLLFVVLYYSIIGLHLFMGITE 269
Query: 287 QKCVKV-FPEDGSWGNLTDEN-----WERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGY 340
Q+C + P + W + D WE C +E ++ G DY L N +
Sbjct: 270 QRCRETPEPVNEDWKAVDDIKFLCGIWE--C-SENSYCGSLADYNLPRNRTEN------- 319
Query: 341 VCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQLFF-VVIIFLGSFYLVNLI 399
++ FG +G+ FD F ++ F + W +F+ + ++ +FY V+LI
Sbjct: 320 -VIEQFG----FGFIRFDDFFYSLFVVFTFLNVTGWSGTTFMFWRAMTTYITAFYFVSLI 374
Query: 400 LAI 402
+
Sbjct: 375 FIL 377
>UniRef50_Q4SSZ6 Cluster: Chromosome undetermined SCAF14338, whole
genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome undetermined SCAF14338, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1670
Score = 187 bits (455), Expect = 3e-45
Identities = 127/457 (27%), Positives = 232/457 (50%), Gaps = 39/457 (8%)
Query: 1351 LLVCLIFWLIFAIMGV-QLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNF 1409
+LV LI I+G+ +LF GK+F C + +++ K+ C NY W NF
Sbjct: 1224 ILVSLISNSGTKILGMLRLFKGKFFVCQGEDVRNVTN-----KSDCLQANYKWVRHKYNF 1278
Query: 1410 DHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRET---NIYMYLYXXXXXXXXXX 1466
D++G+A + LF +A+ GW+ IM D +D+ V +Q NI++ +
Sbjct: 1279 DNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQLTSRNYPKNIWLTISFLLIRKKETL 1338
Query: 1467 XTLNLFIGV--IIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWR 1524
+L + V ++ +++ + L MF D A K P + P
Sbjct: 1339 NSLQKGVPVYYLVSSYDPPSPRPLTPLPMFHPHDFPFPTEAQSK-----PYYSDYSPT-- 1391
Query: 1525 PQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECL 1584
+ ++ ++ T D+ I + IGLN++ M+++HYQQ E + L N IF +IF E +
Sbjct: 1392 -RLLIHKMCTSHYLDLFITIVIGLNVIAMSMEHYQQPEELTEALKICNYIFTLIFVLESV 1450
Query: 1585 LKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYF-VSPTLLRVVRVAKVGRVL 1642
K+ A + +F + WN D V+V+ SI+ + L I E ++PT++R++RV ++ RVL
Sbjct: 1451 FKLVAFGFRRFFKDKWNQLDLVIVLLSIMGITLEKIEEASLPINPTIIRIMRVLRIARVL 1510
Query: 1643 RLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHV-KDKGGLDDVY- 1700
+L+K A G+R LL + +LP + N+ LL L+ FIFA G+ F + KD D+++
Sbjct: 1511 KLLKMAVGMRALLDTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLSKDTCICDELHP 1570
Query: 1701 --------NFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATI 1752
FK F + +LLF++ST W+G++ + +C C + +
Sbjct: 1571 CEGLGRYATFKNFGMAFLLLFRVSTGDNWNGIMKDTL--RDC------AHETTTCYNTVV 1622
Query: 1753 GITYLLSYLVISFLIVINMYIAVILENYSQATEDVQE 1789
Y +S+++ + +++N+ IAV++++ ++ ++ +E
Sbjct: 1623 SPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKEAKE 1659
Score = 115 bits (277), Expect = 1e-23
Identities = 83/310 (26%), Positives = 147/310 (47%), Gaps = 24/310 (7%)
Query: 1189 FPFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPIL 1248
FPF P++ + RL K+ + Y + + +I L+ +A+++E P L
Sbjct: 1373 FPFPTEAQSKPYYSDYSPTRLLIHKMCTSHYLDLFITIVIGLNVIAMSMEHYQQPEE--L 1430
Query: 1249 QDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGG 1308
+ L + IFT+IF +E + K +A GF+++F + W LD +IV++S++
Sbjct: 1431 TEALKICNYIFTLIFVLESVFKLVAFGFRRFFKDKWNQLDLVIVLLSIMGITLEKIEEAS 1490
Query: 1309 I----QAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIM 1364
+ + MR LR R L+ + GMR +++ ++QA+P + N+ L+ ++ + IFA +
Sbjct: 1491 LPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQALPQVGNLGLLFMLLFFIFAAL 1550
Query: 1365 GVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVAT 1424
GV+LF G K T + E+ P + L Y F + G A+L LF+V+T
Sbjct: 1551 GVELF-GDLSK-----DTCICDELHPCEG---LGRYA------TFKNFGMAFLLLFRVST 1595
Query: 1425 FKGWIQIMNDAIDSREVGRQPIRETN-IYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQ 1483
W IM D + R+ + N + +Y +N+ I V++ + E
Sbjct: 1596 GDNWNGIMKDTL--RDCAHETTTCYNTVVSPIYFVSFVLTAQFVLVNVVIAVLMKHLEES 1653
Query: 1484 KKKAGGSLEM 1493
K+A EM
Sbjct: 1654 NKEAKEEAEM 1663
Score = 83.8 bits (198), Expect = 4e-14
Identities = 60/213 (28%), Positives = 105/213 (49%), Gaps = 19/213 (8%)
Query: 1523 WRPQAIVFEIVTDKK-FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSS 1581
WR F + D K F IM+ I +N L+M +++++Q + + L+ N++F +FS
Sbjct: 576 WRLVCDTFRKIVDSKYFGRGIMIAILINTLSMGIEYHEQPDELTNALEISNIVFTSLFSL 635
Query: 1582 ECLLKIFAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGR 1640
E LLK+ + Y P+N+FD ++V+ S+ +V L V+R ++ R
Sbjct: 636 EMLLKVLVYGPFGYIKNPYNIFDGIIVVISVWEIVGQ--------QGGGLSVLRTFRLMR 687
Query: 1641 VLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIF--------AIFGMSFFMHVKD 1692
VL+LV+ ++ L L ++ + C+LL L +FIF G F +D
Sbjct: 688 VLKLVRFMPALQRQLVVLMKTMDNVATFCMLLMLFIFIFRTAVSWECICIGCKFGSE-RD 746
Query: 1693 KGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVL 1725
L D NF + + +++ +FQ+ T W+ VL
Sbjct: 747 GDTLPDRKNFDSLLWAIVTVFQILTQEDWNKVL 779
Score = 69.7 bits (163), Expect = 7e-10
Identities = 53/231 (22%), Positives = 111/231 (48%), Gaps = 33/231 (14%)
Query: 210 IALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFS 269
IA+ ++ + + +A+RT RVLR L+ VP ++ +V +++++ L +V++L F
Sbjct: 3 IAMLEYSLNLQSVSFSAVRTVRVLRPLRANNRVPSMRILVTLLLDTLPMLGNVLLLCFFV 62
Query: 270 LSVFALMGLQIYMGVLTQKCV--KVFP--------------EDGSWGNLTDENWERFCQN 313
+F ++G+Q+++G L +C FP E+ + +N R C +
Sbjct: 63 FFIFGIVGVQLWVGRLRNRCFVEDTFPFPLSHKYYHTENDDENPFICSQPKDNGMRDCNS 122
Query: 314 ETNWYGEGG---DYPLCGNSSGAGQC---EPGYVCLQGFGPNPNYGYTSFDTFGWAFLSA 367
+ EGG + + N + C Y NP G +FD +A+++
Sbjct: 123 VPKLFEEGGVQCNLDMYSNITDNTTCINWNQYYTNCSDSTINPFKGAINFDNIFYAWIAI 182
Query: 368 FRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
F+++T + W ++ ++F+++I +GSF+++NL L ++A +
Sbjct: 183 FQVITLEGWVDIMYFVMDAHSFYNFIYFILLIIIGSFFMINLCLVVIATQF 233
Score = 67.3 bits (157), Expect = 4e-09
Identities = 29/62 (46%), Positives = 44/62 (70%)
Query: 1311 AFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
+F +RT+R LRPLRA +R+ MR++V L+ +P + NVLL+C + IF I+GVQL+
Sbjct: 16 SFSAVRTVRVLRPLRANNRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWV 75
Query: 1371 GK 1372
G+
Sbjct: 76 GR 77
Score = 65.7 bits (153), Expect = 1e-08
Identities = 43/145 (29%), Positives = 77/145 (53%), Gaps = 5/145 (3%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
K++++ YF ++ IL+++L++ +E P L + L + +FT +F +EML+K L
Sbjct: 585 KIVDSKYFGRGIMIAILINTLSMGIEYHEQPDE--LTNALEISNIVFTSLFSLEMLLKVL 642
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG 1332
G Y N + D IIV++S+ V GG+ +T R +R L+ +R M +Q
Sbjct: 643 VYGPFGYIKNPYNIFDGIIVVISVWEIVGQ--QGGGLSVLRTFRLMRVLKLVRFMPALQR 700
Query: 1333 MRVVVNALVQAIPSIFNVLLVCLIF 1357
VV+ + + + F +LL+ IF
Sbjct: 701 QLVVLMKTMDNV-ATFCMLLMLFIF 724
Score = 63.7 bits (148), Expect = 5e-08
Identities = 31/112 (27%), Positives = 66/112 (58%), Gaps = 5/112 (4%)
Query: 163 TPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALA-YVTMGIDL 221
T +E + ++FT +++ E +KV+ G PF Y+++ +N D +++ ++ + +G
Sbjct: 619 TNALEISNIVFTSLFSLEMLLKVLVYG----PFGYIKNPYNIFDGIIVVISVWEIVGQQG 674
Query: 222 GNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVF 273
G L+ LRTFR++R LK V +P L+ + +++++ N+ +L M + +F
Sbjct: 675 GGLSVLRTFRLMRVLKLVRFMPALQRQLVVLMKTMDNVATFCMLLMLFIFIF 726
Score = 58.8 bits (136), Expect = 1e-06
Identities = 35/134 (26%), Positives = 66/134 (49%), Gaps = 11/134 (8%)
Query: 114 RFSATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEV-- 171
R T +L++ P + R + I+ H LF ++ I +NCI + M P ++ T
Sbjct: 1112 RHRNTWSLYLFSPESRFRALCNQIITHKLFDHIVLVIIFLNCITIAMER-PRIDPTSAER 1170
Query: 172 --------IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN 223
IFT I+ E ++K++A G+ YLR +WN LD +++ ++ + + + L +
Sbjct: 1171 IFLTLSNYIFTAIFVAEMSIKIVALGWCFGDKAYLRSSWNILDGMLVLISVIDILVSLIS 1230
Query: 224 LAALRTFRVLRALK 237
+ + +LR K
Sbjct: 1231 NSGTKILGMLRLFK 1244
Score = 58.4 bits (135), Expect = 2e-06
Identities = 43/181 (23%), Positives = 86/181 (47%), Gaps = 21/181 (11%)
Query: 127 FNPIRRVAIYILVHPLFSLFIITTILVNCILMIMP-------TTPTVESTEVIFTGIYTF 179
++P R + + LFI I +N I M M T ++ IFT I+
Sbjct: 1388 YSPTRLLIHKMCTSHYLDLFITIVIGLNVIAMSMEHYQQPEELTEALKICNYIFTLIFVL 1447
Query: 180 ESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAAL----------RT 229
ES K++A GF + +D WN LD V++ L+ + + ++ A+L R
Sbjct: 1448 ESVFKLVAFGFR----RFFKDKWNQLDLVIVLLSIMGITLEKIEEASLPINPTIIRIMRV 1503
Query: 230 FRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKC 289
R+ R LK + + G++ ++ V++++ + ++ +L M +FA +G++++ + C
Sbjct: 1504 LRIARVLKLLKMAVGMRALLDTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLSKDTC 1563
Query: 290 V 290
+
Sbjct: 1564 I 1564
Score = 51.2 bits (117), Expect = 3e-04
Identities = 30/111 (27%), Positives = 59/111 (53%), Gaps = 4/111 (3%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
++I + F+ V+ +I L+ + +A+E + + L + IFT IF EM IK +
Sbjct: 1134 QIITHKLFDHIVLVIIFLNCITIAMERPRIDPTSAERIFLTLSNYIFTAIFVAEMSIKIV 1193
Query: 1273 ALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLR 1319
ALG+ + Y ++W LD ++V++S+I+ + +L G + +R +
Sbjct: 1194 ALGWCFGDKAYLRSSWNILDGMLVLISVIDILVSLISNSGTKILGMLRLFK 1244
Score = 45.6 bits (103), Expect = 0.014
Identities = 31/100 (31%), Positives = 53/100 (53%), Gaps = 5/100 (5%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFG---KNYVDYVD 890
RV KL K + L+ + + + +GNL + ++ FIFA +G++LFG K+ +
Sbjct: 1508 RVLKLLKMAVGMRALLDTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLSKDTCICDE 1567
Query: 891 RFPDGDLPRW-NFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
P L R+ F +F +F+++FRV G+ W M D +
Sbjct: 1568 LHPCEGLGRYATFKNFGMAFLLLFRVSTGDNWNGIMKDTL 1607
Score = 41.5 bits (93), Expect = 0.23
Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
Query: 1633 VRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM-HVK 1691
VR +V R LR +R L+ L +LP L N+ LL F V FIF I G+ ++ ++
Sbjct: 20 VRTVRVLRPLRANNRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWVGRLR 79
Query: 1692 DKGGLDDVYNF 1702
++ ++D + F
Sbjct: 80 NRCFVEDTFPF 90
Score = 41.1 bits (92), Expect = 0.30
Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 10/80 (12%)
Query: 1407 MNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXX 1466
+NFD++ A++ +FQV T +GW+ IM +D+ + Y ++Y
Sbjct: 170 INFDNIFYAWIAIFQVITLEGWVDIMYFVMDAH----------SFYNFIYFILLIIIGSF 219
Query: 1467 XTLNLFIGVIIDNFNEQKKK 1486
+NL + VI F+E K++
Sbjct: 220 FMINLCLVVIATQFSETKQR 239
Score = 37.5 bits (83), Expect = 3.7
Identities = 16/64 (25%), Positives = 36/64 (56%)
Query: 818 NMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMG 877
N+ A+++ LR + P++ +L++++ T+ LGN+ + + FIF ++G
Sbjct: 11 NLQSVSFSAVRTVRVLRPLRANNRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVG 70
Query: 878 MQLF 881
+QL+
Sbjct: 71 VQLW 74
Score = 36.7 bits (81), Expect = 6.4
Identities = 18/63 (28%), Positives = 36/63 (57%), Gaps = 11/63 (17%)
Query: 356 SFDTFGWAFLSAFRLMTQDYWEN-LYQ----------LFFVVIIFLGSFYLVNLILAIVA 404
+FD+ WA ++ F+++TQ+ W LY L+F+ ++ G++ L NL++AI+
Sbjct: 755 NFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSPVAALYFIALMTFGNYVLFNLLVAILV 814
Query: 405 MSY 407
+
Sbjct: 815 EGF 817
Score = 36.7 bits (81), Expect = 6.4
Identities = 13/38 (34%), Positives = 28/38 (73%)
Query: 796 FVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYL 833
+++LFIT+ I +N + M+++H+ +++ +ALK NY+
Sbjct: 1403 YLDLFITIVIGLNVIAMSMEHYQQPEELTEALKICNYI 1440
>UniRef50_Q00ST7 Cluster: Voltage-gated Ca2+ channels, alpha1
subunits; n=1; Ostreococcus tauri|Rep: Voltage-gated Ca2+
channels, alpha1 subunits - Ostreococcus tauri
Length = 1005
Score = 182 bits (443), Expect = 9e-44
Identities = 131/477 (27%), Positives = 226/477 (47%), Gaps = 28/477 (5%)
Query: 1330 MQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEII 1389
+ G+R+VVN ++ +IP++ V L+ L IFA++G++ F G+++ C +
Sbjct: 212 VSGVRLVVNTVISSIPAVSYVCLLGLASMSIFALLGMEFFMGEFWSCRAVEDA----RSY 267
Query: 1390 PDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRET 1449
+ AC W N+ NFD+ G A L F + W +IM A+DS G ++
Sbjct: 268 TTRGACEAAGGVWRNAKFNFDNFGAALLSTFILHAGDDWQEIMWFAMDSTGYGTGYKQDN 327
Query: 1450 NIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKM 1509
N Y +NL ++DNFN K A F T Q+++ AM +
Sbjct: 328 NQSAAAYFVITVLIGNFFWVNLLATALVDNFN---KMASQDKLTFATPAQRRWQQAMMRA 384
Query: 1510 GSKKP---LKAIPRPR---W-RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSE 1562
+ K +P P W R + + K F ++ + N++T + S+
Sbjct: 385 AAADLGAWRKIVPPPGNGLWSRARLAAHTVAKAKTFSFFVVGVVTANLMTALAETANMSQ 444
Query: 1563 TFSAVLDYLNMIFIVIFSSECLLKIFAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDIIE 1621
+ YLN F +I+ E ++ + A + Y + WN D VV+ S++ DII
Sbjct: 445 AEINIHYYLNTTFTIIYVLEMVILLMAQGKKRYLLTYWNWLDSFVVVVSVV-----DIIG 499
Query: 1622 KYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAI 1681
+ F ++ +++ ++ R+L+LV G+R+L MS+PA+ N+ L L +F +AI
Sbjct: 500 QSFEVGGIMAYLKLVRLLRLLKLVNAHAGLRSLFTTFIMSIPAVANVAALSALAIFAYAI 559
Query: 1682 FGMSFFMHVK---DKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEEC--DL 1736
G+S F + + G + + +NF++F + L + T GW G + E C D
Sbjct: 560 MGVSLFGDKRGPYEGGTVSNYFNFESFPTAFAALMGVYT-GGWVGTFGELYQTEACLRDE 618
Query: 1737 PDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTD 1793
P S +C I I Y +S++V+S ++ N+++A+ILE +S T D QEG+ D
Sbjct: 619 PPFMSESSIDCDYNYIAIPYFISFVVVSIFLLGNLFVAIILERFS-VTAD-QEGVYD 673
Score = 92.3 bits (219), Expect = 1e-16
Identities = 48/169 (28%), Positives = 89/169 (52%), Gaps = 4/169 (2%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W RL + + F V+ ++ + + E ++ I +I YY++ FT+I+
Sbjct: 404 WSRARLAAHTVAKAKTFSFFVVGVVTANLMTALAETANMSQAEI--NIHYYLNTTFTIIY 461
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRP 1323
+EM+I +A G ++Y W WLD +V+VS+++ + GGI A+ ++ +R LR
Sbjct: 462 VLEMVILLMAQGKKRYLLTYWNWLDSFVVVVSVVDIIGQSFEVGGIMAY--LKLVRLLRL 519
Query: 1324 LRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGK 1372
L+ ++ G+R + + +IP++ NV + + +AIMGV LF K
Sbjct: 520 LKLVNAHAGLRSLFTTFIMSIPAVANVAALSALAIFAYAIMGVSLFGDK 568
Score = 60.1 bits (139), Expect = 6e-07
Identities = 41/151 (27%), Positives = 75/151 (49%), Gaps = 17/151 (11%)
Query: 143 FSLFIITTILVNCILMIMPTTPTVESTEV--------IFTGIYTFESAVKVMARGFILQP 194
FS F++ + N ++ + T + E+ FT IY E + +MA+G
Sbjct: 420 FSFFVVGVVTAN-LMTALAETANMSQAEINIHYYLNTTFTIIYVLEMVILLMAQG----K 474
Query: 195 FTYLRDAWNWLDFVVIALAYVTM---GIDLGNLAA-LRTFRVLRALKTVAIVPGLKTIVG 250
YL WNWLD V+ ++ V + ++G + A L+ R+LR LK V GL+++
Sbjct: 475 KRYLLTYWNWLDSFVVVVSVVDIIGQSFEVGGIMAYLKLVRLLRLLKLVNAHAGLRSLFT 534
Query: 251 AVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
I S+ + +V L+ ++ +A+MG+ ++
Sbjct: 535 TFIMSIPAVANVAALSALAIFAYAIMGVSLF 565
Score = 40.7 bits (91), Expect = 0.40
Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 5/96 (5%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
LK LR+ KL + L L + ++ A+ N+ + + IF +A+MG+ LFG
Sbjct: 511 LKLVRLLRLLKLVNAHAGLRSLFTTFIMSIPAVANVAALSALAIFAYAIMGVSLFG---- 566
Query: 887 DYVDRFPDGDLPRW-NFTDFMHSFMIVFRVLCGEWI 921
D + G + + NF F +F + V G W+
Sbjct: 567 DKRGPYEGGTVSNYFNFESFPTAFAALMGVYTGGWV 602
Score = 39.1 bits (87), Expect = 1.2
Identities = 16/42 (38%), Positives = 29/42 (69%)
Query: 242 VPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
V G++ +V VI S+ + V +L + S+S+FAL+G++ +MG
Sbjct: 212 VSGVRLVVNTVISSIPAVSYVCLLGLASMSIFALLGMEFFMG 253
>UniRef50_Q22XZ8 Cluster: Cation channel family protein; n=1;
Tetrahymena thermophila SB210|Rep: Cation channel family
protein - Tetrahymena thermophila SB210
Length = 1875
Score = 181 bits (440), Expect = 2e-43
Identities = 138/527 (26%), Positives = 251/527 (47%), Gaps = 39/527 (7%)
Query: 1335 VVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCV--DMNHTTLS--HEIIP 1390
++VN+L Q IP + ++ V LI IFAI + F G+ C D+N+ S ++ I
Sbjct: 1174 LLVNSLFQTIPVLTSLAFVILIMTWIFAIFLMSSFKGELQYCSFDDINNMVDSDLYKKIV 1233
Query: 1391 DKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETN 1450
C W N NFD V + + LF++ + W Q+M +ID+ + +QPI++
Sbjct: 1234 TIQDCNQSGGQWVNQYFNFDTVFLSVISLFKIILGENWTQLMWSSIDASGIEKQPIKDYQ 1293
Query: 1451 IYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMG 1510
L T NL G++++NF K + G + T Q+++ K M
Sbjct: 1294 RGYALIYLLLLFMGNIFTTNLITGLVVNNFKRIKDEISGYKNL--TSIQRQWVEMQKYMM 1351
Query: 1511 SKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDY 1570
+K IP P + + + KF+ II+ FI LN++TM + + + ++
Sbjct: 1352 KRKLKVVIPTPENTYRHFCYILAKSSKFEKIIIFFIILNLVTMGCQYKGMDDQGAYAINV 1411
Query: 1571 LNMIFIVIFSSECLLKIFALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTL 1629
+N + I+ E L+KI + Y YF + WN FDF V++ + + L S + VS L
Sbjct: 1412 INNFCLGIYHVEALIKIVGVGVYFYFKDDWNKFDFGVILITDIVLFSSIFVSTSTVS-NL 1470
Query: 1630 LRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMH 1689
+ R ++GR+++ V L+ ++ LP+L NI L+FL+ FI AI GM+ F
Sbjct: 1471 PIIFRALRLGRIVKYV--------LIDSIYYLLPSLINIAFLVFLIAFICAILGMNLFSQ 1522
Query: 1690 VKDKGG------LDD------VYNFKTFVQSMILLFQMSTSAGWDGVLDGI-INEEEC-- 1734
V+ G D YNF+TF S +++ Q + WD + ++ C
Sbjct: 1523 VQLLDGDQQYPFFDSRAPYPYSYNFQTFTGSFLVILQCIQNQNWDWYIQQYGFDQSGCYS 1582
Query: 1735 -DLPDNERGSPGNCGSATIGITYLLSYLVISFL--IVINMYIAVILENYSQATEDVQEGL 1791
D ++ C + ++Y +V+ FL I+IN+++A+++E + ++ + +
Sbjct: 1583 QSYSDQQQDGIKGCSNP---LSYPFFLVVVFFLRYIIINLFLALVIEGFFDTLKENEAVI 1639
Query: 1792 TDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHKPNKY 1838
+ + + E W +D +G+ +I +++ +L +L+ P I N++
Sbjct: 1640 SPEVLESIIEKWSVYDQNGTGFIDPEEM--YLLLLDIPEPIGLKNEF 1684
Score = 50.8 bits (116), Expect = 4e-04
Identities = 59/257 (22%), Positives = 103/257 (40%), Gaps = 25/257 (9%)
Query: 169 TEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALR 228
T+ + + E +K++ARG +YL++ N + +V + V L R
Sbjct: 206 TKYFYISYFAIEIVLKIIARGLYQSYNSYLKNINNLIILIVFGI-IVIYDTSFIFLFIFR 264
Query: 229 TFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQK 288
F V + + I+ S + L ++ L F +++F ++ I+ G L +
Sbjct: 265 IFYVFEFTSNIKQLRKSYIILKLYQISGETLFKLLFLIFFFITLFGILSTNIFSGSLDYR 324
Query: 289 C-VKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFG 347
C P G W + R C + D CG++ + + Y+
Sbjct: 325 CRTTPVPGQGDWE--LAQGVYRVCGGRFSC----PDNTYCGSNYSYIKNDTSYIDSANMD 378
Query: 348 -PNP----NYGYTSFDTFGWAFLSAFRL-MTQDYWENLYQL-----FFVVIIFLGSFYLV 396
P NYG T+FD +L+ F M + Y+ LY + F+ IIF+ ++LV
Sbjct: 379 KPTSSRYYNYGITNFDNLYQTYLTLFLFYMVEGYYNVLYMMEDSHDQFIPIIFVTCYFLV 438
Query: 397 ------NLILAIVAMSY 407
NLI+AI + Y
Sbjct: 439 CTYFLNNLIIAIFFIKY 455
Score = 45.2 bits (102), Expect = 0.018
Identities = 36/166 (21%), Positives = 78/166 (46%), Gaps = 10/166 (6%)
Query: 1206 TLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFI 1265
T R + L +++ FE +I I+L+ + + + + + + ++ I+ +
Sbjct: 1365 TYRHFCYILAKSSKFEKIIIFFIILNLVTMGCQYKGMDDQGAYA--INVINNFCLGIYHV 1422
Query: 1266 EMLIKWLALGFQKYFTNAWCWLDF-IIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPL 1324
E LIK + +G YF + W DF +I++ ++ F + + + RALR
Sbjct: 1423 EALIKIVGVGVYFYFKDDWNKFDFGVILITDIVLFSSIFVSTSTVSNLPII--FRALRLG 1480
Query: 1325 RAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
R + V+++++ +PS+ N+ + + I AI+G+ LF+
Sbjct: 1481 RIVK-----YVLIDSIYYLLPSLINIAFLVFLIAFICAILGMNLFS 1521
>UniRef50_A0BF12 Cluster: Chromosome undetermined scaffold_103, whole
genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_103, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 2368
Score = 175 bits (427), Expect = 8e-42
Identities = 149/679 (21%), Positives = 299/679 (44%), Gaps = 56/679 (8%)
Query: 1183 EQCYQKFPFLAGDDDSP---FWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALED 1239
EQ + KF F ++ + R ++ I + T + ++ L + +
Sbjct: 1386 EQLFAKFQFFTNNESENSLYIFSKQNQFRKLCYRCINYQLYITLIQFTFFIALLNMCVHT 1445
Query: 1240 VHLPHRPILQDILY----YMDRIFTVIFFIEMLIKWLALGFQK----YFTNAWCWLDFII 1291
I +D++ Y++ ++ I+ ++K ++LGF K + + W ++DF+
Sbjct: 1446 YFDYENKISKDLIVQISNYVELTTNILLLIDSILKIISLGFMKDKGSFTSEFWRFIDFVY 1505
Query: 1292 VMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVL 1351
+ + N++ AF+ ++ ++ RP R + + ++ + +A+ ++I + N+L
Sbjct: 1506 QLCYITNYIVKY------DAFQYLKAIKYARPFRFLYLFEQLKYINSAISKSIVDLMNIL 1559
Query: 1352 LVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDH 1411
V ++ WLIFAI GV L+ K C L+ I +K C E W N+ NFD+
Sbjct: 1560 FVQIMVWLIFAIFGVMLYKDKMSYC----KYPLNFGI--NKQECIEEGEEWVNNLYNFDN 1613
Query: 1412 VGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYL-YXXXXXXXXXXXTLN 1470
+G A L L+++ W+ IM ++SR + PI N ++ L Y L
Sbjct: 1614 MGNAMLALYRMTACDDWVYIMQICLNSRAEDQGPILYGNRWVTLIYFMLFILVGVLFFLG 1673
Query: 1471 LFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVF 1530
F G++ NF K K + +T DQ+ + N + + + P + P P+ + +
Sbjct: 1674 FFAGILFINFQTYKTKL---QKQILTNDQQLFANITEIIQKEVPNYSDP-PKSFIRKLAS 1729
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL 1590
I+ ++ +I+L I +N +T + S L+Y+ + LKI A
Sbjct: 1730 NIIKQSLYERMILLTIFINTGILTFFYDDASLELLQTLEYIYHALSCFLILDTCLKILAF 1789
Query: 1591 RY-HYFVEPWNLFDFVVVMFSILSLVL------------SDIIEKYFVSPTLLRVVRVAK 1637
Y+ W +F++ + +++ L+L S I +KYF+ +LR+ +
Sbjct: 1790 GIRRYWGYIWREIEFILGIIALIDLILFLTINWSQYYFKSTINDKYFL---ILRLAFACR 1846
Query: 1638 VGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLD 1697
R L +++ KG+ LL L S L I F ++ + G +F ++ +
Sbjct: 1847 NLRTLLIIQQFKGLTRLLRILNFSASFLLQILCFFFSILLFYGFIGCEYFGMIEKGAYVT 1906
Query: 1698 DVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATI-GITY 1756
D NF +++++LF++ T W ++ + + P+ +P CG I +
Sbjct: 1907 DYMNFTNIGKALLILFKICTKNNWIRIMIDVSERNQYCTPE----TPSYCGVKWIYANIF 1962
Query: 1757 LLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTD--DDYDMYYEIWQRFDPD--GSQ 1812
++++IS + N++I +++ + + L ++ D + W ++ + G+Q
Sbjct: 1963 FYTFVLISNFVAFNLFITALVDQFEKFFNSQNSVLQTYIENIDPFRTTWCKYSTETKGAQ 2022
Query: 1813 -YIRYDQLSDFLDVLEPPL 1830
+ RY L+ FL L PPL
Sbjct: 2023 MHSRY--LAHFLLELGPPL 2039
Score = 50.4 bits (115), Expect = 5e-04
Identities = 47/225 (20%), Positives = 101/225 (44%), Gaps = 13/225 (5%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
K+I + F T ++ + ++ ++ + +E + +Q L +I F E ++K +
Sbjct: 441 KIINHRIF-TILVLISIIFNIMVFIESQSENLQTDVQASLRQQKQIILFFFIAENILKLI 499
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG 1332
G +F + D II+++ ++ I F T R L+ L + S+
Sbjct: 500 GQGVIDFFWDLQNVFDMIILILFSFHYYYPTLM---IIDFSTARLLKILSVISVFSKR-- 554
Query: 1333 MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKC------VDMNHTTLS 1385
+++++ AL ++ + LL+ +IF FA+ G+ LF G + +KC + N+
Sbjct: 555 LQIMLLALKHSLRFLLESLLIVVIFSYFFALFGMHLFQGLFLYKCYHAESGIQTNYLCGY 614
Query: 1386 HEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQ 1430
+ D + ++ T N P NFD + ++ + ++ F W +
Sbjct: 615 NLECQDYSMICCKSLTNPNVPTNFDDIFYSFQEVVRLMIFNEWTE 659
Score = 44.8 bits (101), Expect = 0.024
Identities = 62/299 (20%), Positives = 131/299 (43%), Gaps = 55/299 (18%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVEST--------EVIFTGIYTFES 181
I A I+ H +F++ ++ +I+ N ++ I + +++ + I + E+
Sbjct: 435 IANTANKIINHRIFTILVLISIIFNIMVFIESQSENLQTDVQASLRQQKQIILFFFIAEN 494
Query: 182 AVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAI 241
+K++ +G I + D N D +++ L + T R+L+ L +++
Sbjct: 495 ILKLIGQGVI----DFFWDLQNVFDMIILILFSFHYYYPTLMIIDFSTARLLKILSVISV 550
Query: 242 VPG-LKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWG 300
L+ ++ A+ S++ L + +++ + FAL G+ ++ G+ KC E G
Sbjct: 551 FSKRLQIMLLALKHSLRFLLESLLIVVIFSYFFALFGMHLFQGLFLYKCYHA--ESGI-- 606
Query: 301 NLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEP-GYVCLQGFGPNPNYGYTSFDT 359
+TN+ LCG + +C+ +C + NPN T+FD
Sbjct: 607 -------------QTNY--------LCGYNL---ECQDYSMICCKSL-TNPNVP-TNFDD 640
Query: 360 FGWAFLSAFRLMTQDYW-ENLYQ----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
++F RLM + W E +Y ++F+ +IF+ + + NLI+A++ + Y
Sbjct: 641 IFYSFQEVVRLMIFNEWTEPIYLAMLTFHDFAIIYFIFLIFIIAIFGANLIIAVLKIYY 699
Score = 44.8 bits (101), Expect = 0.024
Identities = 24/103 (23%), Positives = 54/103 (52%), Gaps = 2/103 (1%)
Query: 180 ESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGNLAALRTFRVLRALKT 238
+S +K+++ GF+ ++ + W ++DF V L Y+T I L+ + R +
Sbjct: 1476 DSILKIISLGFMKDKGSFTSEFWRFIDF-VYQLCYITNYIVKYDAFQYLKAIKYARPFRF 1534
Query: 239 VAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+ + LK I A+ +S+ +L +++ + + +FA+ G+ +Y
Sbjct: 1535 LYLFEQLKYINSAISKSIVDLMNILFVQIMVWLIFAIFGVMLY 1577
Score = 44.4 bits (100), Expect = 0.032
Identities = 35/159 (22%), Positives = 73/159 (45%), Gaps = 10/159 (6%)
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSET-FSAVLDYLNMIFIVIFSSECLLKIFA 1589
+I+ + F +++++ I N++ + +T A L I + F +E +LK+
Sbjct: 441 KIINHRIFTILVLISIIFNIMVFIESQSENLQTDVQASLRQQKQIILFFFIAENILKLIG 500
Query: 1590 LRY-HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGA 1648
+F + N+FD ++++ ++ F + LL+++ V V +
Sbjct: 501 QGVIDFFWDLQNVFDMIILILFSFHYYYPTLMIIDFSTARLLKILSVISVF--------S 552
Query: 1649 KGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
K ++ +L AL SL L L++ + + FA+FGM F
Sbjct: 553 KRLQIMLLALKHSLRFLLESLLIVVIFSYFFALFGMHLF 591
Score = 43.2 bits (97), Expect = 0.074
Identities = 29/127 (22%), Positives = 60/127 (47%), Gaps = 3/127 (2%)
Query: 1249 QDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLIN--FVAALCGA 1306
Q+I+ ++ F I E+ +K + G +++ T A ++D I+ S+I +V G
Sbjct: 1104 QNIIRQLNDYFVFILLGELFLKLVFQGIKRFCTRANNFVDTFILTCSIIQSVYVNQNSGK 1163
Query: 1307 GGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGV 1366
G I + + +AL R + + +++PS N++ + + FA +G+
Sbjct: 1164 GNIY-LDLLNSSQALLIYRIIKYNNFALKIAKITKKSLPSFLNLIFLMITLIFCFAFIGM 1222
Query: 1367 QLFAGKY 1373
L+ GK+
Sbjct: 1223 NLYKGKF 1229
Score = 39.9 bits (89), Expect = 0.69
Identities = 58/277 (20%), Positives = 116/277 (41%), Gaps = 40/277 (14%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVE 1597
FD+I+++ N+L +++ Y + DY F+ I E LK+ F
Sbjct: 1085 FDLIVLI----NILLLSMIGYVDQNIIRQLNDY----FVFILLGELFLKLVFQGIKRFCT 1136
Query: 1598 PWNLF--DFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLL 1655
N F F++ I S+ ++ K + LL + + R+++ A I +
Sbjct: 1137 RANNFVDTFILTCSIIQSVYVNQNSGKGNIYLDLLNSSQALLIYRIIKYNNFALKIAKIT 1196
Query: 1656 FALAMSLPALFNICLLLFLVMFIFAIFGMSFF---MHVKDKGGLDDVYNFKTFVQSMILL 1712
SLP+ N+ L+ ++F FA GM+ + + GL +F + + +
Sbjct: 1197 ---KKSLPSFLNLIFLMITLIFCFAFIGMNLYKGKFPINTDFGLQQ--SFDDLAAAFLTV 1251
Query: 1713 FQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITY--LLSYLVISFLIVIN 1770
F + + W G++ G+ S+ IG T+ ++S V++ L+ I
Sbjct: 1252 FVRAANEDWFGMV-----------------MLGSQYSSKIGTTFFSVISVYVLN-LMTIG 1293
Query: 1771 MYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFD 1807
+A++L+++S + + G +D D + I + D
Sbjct: 1294 FILAIVLDSFSSYENETESG--EDRLDSQFSILEGND 1328
Score = 37.9 bits (84), Expect = 2.8
Identities = 32/128 (25%), Positives = 62/128 (48%), Gaps = 11/128 (8%)
Query: 796 FVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRT 855
FV+ FI C ++ ++++ + + +D L S L ++++ K + I ++
Sbjct: 1141 FVDTFILTCSIIQSVYVNQNSGKGNIYLD-LLNSSQALLIYRIIKYNNFALKIAKITKKS 1199
Query: 856 MGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP-DGDLP-RWNFTDFMHSFMIVF 913
+ + NL F++ +IF FA +GM L Y +FP + D + +F D +F+ VF
Sbjct: 1200 LPSFLNLIFLMITLIFCFAFIGMNL-------YKGKFPINTDFGLQQSFDDLAAAFLTVF 1252
Query: 914 -RVLCGEW 920
R +W
Sbjct: 1253 VRAANEDW 1260
>UniRef50_A0CBV7 Cluster: Chromosome undetermined scaffold_165, whole
genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_165, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 2018
Score = 175 bits (426), Expect = 1e-41
Identities = 136/601 (22%), Positives = 277/601 (46%), Gaps = 37/601 (6%)
Query: 1248 LQDILYYMDRIFTVI-FFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGA 1306
L D L + I +I F + ++ K L L + + W +D I ++ I + +
Sbjct: 1224 LPDTLQLIVNILIIIDFLLNIISKGLILDRGSHIQSIWQIVDIIYIIAYFIQYHRS---- 1279
Query: 1307 GGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGV 1366
+ L RP+ M R+ + + AL Q++ I NVL+ L W +F + G+
Sbjct: 1280 NYAPIVDVLMFLGYFRPMILMYRISWLIQLRAALAQSLVDILNVLITLLSVWFVFGVYGI 1339
Query: 1367 QLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFK 1426
L+ ++ C D +S+E C +N TW N NFD++ A LF V+TF
Sbjct: 1340 ILYENQFGFCEDKMEFYVSYE------ECQSQNRTWVNYKHNFDNITVAIPTLFVVSTFD 1393
Query: 1427 GWIQIMNDAIDSR--EVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQK 1484
GW +I+ A +S+ ++G P ++ +Y Y + L+LF GV+ N E +
Sbjct: 1394 GWGEILQVAENSQIADIGPVPF-DSYLYTYFFLIIFCFIGSMFFLSLFTGVLFTNLKENQ 1452
Query: 1485 KKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIML 1544
K + +++ Q+++ + + S P+ + P P++ + + +IV + + I
Sbjct: 1453 FKMQNNE---LSQVQREFKSITNIIMSDFPIYSTP-PKYGVRKMASDIVNNHRVKQCIFA 1508
Query: 1545 FIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFD 1603
F+ ++++ + L + + V++ ++ +++ +L + AL + +F W F
Sbjct: 1509 FLIMDLVILLLFRSEMDRDYFLVINSIHHSLTILYLLWIILMVLALGVNRFFDNNWRRFY 1568
Query: 1604 FVVVMFSILSLVLSDIIE----KYFVSPT-----LLRVVRVAKVGRVLRLVKGAKGIRTL 1654
F +++ ++ L+ I + +Y+ SP L R + R++ + +G I+ L
Sbjct: 1569 FFLILVGMIDLIAHYITDWTRVQYYSSPNEQYYQLYRFFFALRSLRIILIFQGLINIQRL 1628
Query: 1655 LFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQ 1714
+ +A ++P L I +L + MFIFA+FG + + +DD+ NF F +M+ LF+
Sbjct: 1629 IRVMAFAVPYLVKIFTILIITMFIFALFGCQLYGKIDSGQVMDDLINFTNFGNAMLALFK 1688
Query: 1715 MSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIA 1774
++ W ++ + D P CGS T + Y + ++++S +++N+++
Sbjct: 1689 CASGDDWRTIMTDTMQHNPLCQED-----PKYCGSPTNQL-YFILFMLLSNYVLLNLFVL 1742
Query: 1775 VILENYSQ--ATEDVQEGLTDDDYDMYYEIWQRFDPD-GSQYIRYDQLSDFLDVLEPPLQ 1831
++E + Q ++ Q ++ D IW ++ + + Y L FL + PL
Sbjct: 1743 GLIEQFEQFFQMQNSQIQTYVENVDDIKTIWCKYTTQTQGKTMHYKFLGKFLMDIGLPLG 1802
Query: 1832 I 1832
+
Sbjct: 1803 V 1803
Score = 62.5 bits (145), Expect = 1e-07
Identities = 56/238 (23%), Positives = 105/238 (44%), Gaps = 12/238 (5%)
Query: 1490 SLEMFMTEDQ-KKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGL 1548
+L F++ DQ KK N +KM L+ I Q + +V+ K D+ L I
Sbjct: 822 NLARFISFDQIKKALNHQEKMIW---LRGISGKIQIAQKYTYIVVSSKFSDLFFDLIILF 878
Query: 1549 NMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWN-LFDFVVV 1607
N + ++L S + D + + E ++K+F+ V WN + ++V
Sbjct: 879 NFVFLSLQGIVNPGLISQIEDITTICLCI----EIVMKLFSFNCKELVSDWNHIVQILIV 934
Query: 1608 MFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFN 1667
+ + L L D I + LR++R K R +K K + + +
Sbjct: 935 SLNFVELTLGDEIGSS--TQQGLRLIRGTKCLLFYRCLKYNKMAAKIGWIAQKTFEQYIY 992
Query: 1668 ICLLLFLVMFIFAIFGMSFFMHVKDKGG-LDDVYNFKTFVQSMILLFQMSTSAGWDGV 1724
+ L+FLV+F++A+ GM + + D+ L +++F ++S + +F + T+ W GV
Sbjct: 993 LTFLMFLVIFMYALIGMEMYAGMFDQNDTLGQLHSFDNIIKSFMTIFNIMTNDDWYGV 1050
Score = 43.2 bits (97), Expect = 0.074
Identities = 32/128 (25%), Positives = 64/128 (50%), Gaps = 15/128 (11%)
Query: 1569 DYLNMIFIVIFSSECLLKIFAL-----RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKY 1623
D + + ++F E ++I A R +F P N++DF++V+ + ++L DII
Sbjct: 260 DNIEQVITILFLIEIGMRIIASGIILNRKSFFRSPLNIYDFLLVILTTMNLYRPDII--- 316
Query: 1624 FVSPTLLRVVRVAK-VGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIF 1682
+ + R++ + +G +L KG+ T+L AL S+ L +++ L F +F
Sbjct: 317 IIDLSPFRMLTLLNYLGDIL------KGLSTMLKALKSSVRLLLEALIIVGLFSLFFGVF 370
Query: 1683 GMSFFMHV 1690
G+ F ++
Sbjct: 371 GVLLFQNL 378
Score = 39.9 bits (89), Expect = 0.69
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 7/97 (7%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LR+ + + + LI +M + L + +L I +FIFA+ G QL+GK +D
Sbjct: 1613 LRIILIFQGLINIQRLIRVMAFAVPYLVKIFTILIITMFIFALFGCQLYGK--IDSGQVM 1670
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCG-EWIESMWDCM 928
D NFT+F ++ + +F+ G +W M D M
Sbjct: 1671 DD----LINFTNFGNAMLALFKCASGDDWRTIMTDTM 1703
>UniRef50_O14234 Cluster: VIC sodium channel; n=1; Schizosaccharomyces
pombe|Rep: VIC sodium channel - Schizosaccharomyces pombe
(Fission yeast)
Length = 1854
Score = 172 bits (419), Expect = 7e-41
Identities = 150/580 (25%), Positives = 261/580 (45%), Gaps = 45/580 (7%)
Query: 1259 FTVIFFIEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGI-QAFK 1313
F IF IE IK +A GF Y + W +DF +++ IN A L + +AF+
Sbjct: 987 FATIFTIEAAIKIIADGFCITPNAYLRSTWNCIDFFVLVTLWINLYAVLTSHALLSRAFR 1046
Query: 1314 TMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
+ LR LR + Q R+ +AL+ IF+ +V + FA+ +F G
Sbjct: 1047 AFKALRVLRLINLTQTSQ--RMFHDALISGFFKIFSAAVVSATLLIPFALWAKNVFGGLL 1104
Query: 1374 FKCVDMNHTTLSHEIIPDKNACTLENY------TWENSP-MNFDHVGKAYLCLFQVATFK 1426
+ C D N + S ++ + A T N+ W N P +FD A L LF++A+ +
Sbjct: 1105 YSCNDDNVLSASQCVL--EYASTPNNWEVWAPRVWSNPPDYDFDRFPHALLALFEIASIE 1162
Query: 1427 GWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
GW+ IM +D QP + ++ L LFI +II N+ E+
Sbjct: 1163 GWVDIMRSVMDITGFNNQPQTNASSGNAMFFVLFNLVSMIYILTLFIAIIISNYAERTGS 1222
Query: 1487 AGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRP---QAIVFEIVTDKKFDMIIM 1543
A F T +Q+ + +K+ S +P K RP RP + + ++ +K +
Sbjct: 1223 A------FFTAEQRAWLELRRKIKSMRPSK---RPAIRPLGLRGLCYDFAV-QKHGIWRR 1272
Query: 1544 LFIGL---NMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEP-W 1599
F GL ++L + Y ++ V + + +I + ++ +K++ L ++YF W
Sbjct: 1273 TFTGLYIVHLLFLLTIFYPCPIAYTYVRNSIFLILSICYTINICVKVYGLSFYYFFHSFW 1332
Query: 1600 NLFDFVVVMFSILSLVLSDIIEKY-FVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFAL 1658
N+FD VV + S+ + I+ K+ S TLL+ + V + L+ L +
Sbjct: 1333 NMFDVVVTLGSLTCNIA--ILAKFENRSLTLLQTTLLVLV--TVHLIPKFDNFDQLSKTV 1388
Query: 1659 AMSLPALFNICLLLFLVMFIFAI-FGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMST 1717
SLP++F++ ++ FAI F F + G + NF++ +++LLF M+
Sbjct: 1389 VASLPSIFSLIATWIVLYITFAIAFNQIFGLTKLGLNGGPN-KNFRSIRNALVLLFTMTF 1447
Query: 1718 SAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVI 1776
GW+ V+ D I+ C D+ S +CG+ +++ +IS I +NM+I V+
Sbjct: 1448 GEGWNDVMHDYTISYPNCVNGDDFYNS--DCGNKPWAYGLFIAWNIISMYIFVNMFITVV 1505
Query: 1777 LENYS--QATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYI 1814
+N+S L +D+ + + W FDP + YI
Sbjct: 1506 FDNFSYIHTKSSSFTNLQRNDFRQFKDSWAPFDPMVTGYI 1545
Score = 65.3 bits (152), Expect = 2e-08
Identities = 38/122 (31%), Positives = 64/122 (52%), Gaps = 5/122 (4%)
Query: 169 TEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAAL- 227
TEV F I+T E+A+K++A GF + P YLR WN +DF V+ ++ + L + A L
Sbjct: 983 TEVAFATIFTIEAAIKIIADGFCITPNAYLRSTWNCIDFFVLVTLWINLYAVLTSHALLS 1042
Query: 228 RTFRVLRALKTVAIVPGLKT----IVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
R FR +AL+ + ++ +T A+I + +++ L FAL ++ G
Sbjct: 1043 RAFRAFKALRVLRLINLTQTSQRMFHDALISGFFKIFSAAVVSATLLIPFALWAKNVFGG 1102
Query: 284 VL 285
+L
Sbjct: 1103 LL 1104
Score = 64.5 bits (150), Expect = 3e-08
Identities = 74/323 (22%), Positives = 142/323 (43%), Gaps = 51/323 (15%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT------TPTVESTEVIFTGIYTF 179
PF+PI R I HPL+++FI I+++ +L+++ + + T++ ++ +YT
Sbjct: 173 PFSPILR---QIYNHPLYNIFIFVVIVLHAVLLMIRSDDPHDKSQTIDYLIIVIGILYTL 229
Query: 180 ESAVKVMARGFIL------------------QPFTYLRDAWNWLDFVVIALAYVTMGIDL 221
E +K+ GF+ + +YLR +WN +DFV I ++++ I
Sbjct: 230 EMLLKIYLFGFLYDGSSSFYDFINSYTKKTPRTMSYLRHSWNRVDFVAIVALWISV-IGK 288
Query: 222 GNLAALRTFRV---LRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGL 278
R F + LR + + I +TI+ ++ ES L V+ F + A++G+
Sbjct: 289 KQQGIFRLFSMIACLRLTRLLNITRKTETILKSLKESSTPLVQVVSFNAFFGVMIAILGV 348
Query: 279 QIYMGVLTQKCVKVFPEDGSW---GNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQ 335
Q + L ++CV + + G +WE + Y + +P N G
Sbjct: 349 QFFKASLNRQCVWLGDYGDQYLPTGQFCGGHWENGIKRA---YLDKNGFPSNVNPRGF-I 404
Query: 336 CEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQD-YWENLYQ----------LFF 384
C VC NP SFD F + F +M+ + + + +Y L F
Sbjct: 405 CAEKSVC--RVVENPYSNTVSFDNFFNSLELIFVIMSSNGFTDIMYDIMDAEYFVSCLLF 462
Query: 385 VVIIFLGSFYLVNLILAIVAMSY 407
++ + + +L++L++A+V S+
Sbjct: 463 IISAYFLTLWLMSLVIAVVTSSF 485
>UniRef50_A0DI39 Cluster: Chromosome undetermined scaffold_51, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_51, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 2023
Score = 169 bits (412), Expect = 5e-40
Identities = 141/594 (23%), Positives = 269/594 (45%), Gaps = 37/594 (6%)
Query: 1253 YYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAF 1312
+Y++ I + + I ++ K L + YF + W LD I ++ I + Q F
Sbjct: 1234 FYINLILAIDYAINVIAKGLFIDNGAYFNSIWQILDVIYIIAFFIQYEKDDYVKPIFQIF 1293
Query: 1313 KTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGK 1372
+ R PL ++R+ + V+ +AL +++ I NVLL W+IF + G+ L+ +
Sbjct: 1294 LYVGYFR---PLNLLNRITILNVLSSALYKSLVDILNVLLTLFSVWIIFGVYGIILYERQ 1350
Query: 1373 YFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIM 1432
+ C D +S++ C +N TW N NFD++ A LF V+TF GW +++
Sbjct: 1351 FGFCEDKMEFRVSYQ------ECIEQNRTWVNFKHNFDNITMAIPTLFTVSTFDGWGEML 1404
Query: 1433 NDA--IDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGS 1490
A D+ VG P + I+ Y++ L+LF GV+ N ++K
Sbjct: 1405 QIAENSDNANVGPVPFN-SYIHTYVFFISFCFVGSMFFLSLFTGVLFSNLKVNQRKIE-- 1461
Query: 1491 LEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNM 1550
+ ++QK++ + P+ + P P + I+ D I + + L++
Sbjct: 1462 -KKDFNQNQKEFIEISDIITKDIPVFSTP-PDNVIRRFASIIMNDNIMQTIFFIVLLLDL 1519
Query: 1551 LTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR-YHYFVEPWNLFDFVVVMF 1609
+ L H + +++Y++ F + + L++ AL + +F W F F++++F
Sbjct: 1520 VNNILFHSDMTTKHLIIINYIHHGFSITITIWGLIQYLALGLFRFFDNYWRQFLFILILF 1579
Query: 1610 SILSLVLS---DIIEKYFVSPTLL---RVVRVAKVGRVLRLV---KGAKGIRTLLFALAM 1660
+I LV+ +E F S L R+ R+ + R LRL+ +G I+ L+ +
Sbjct: 1580 AITDLVIDFEFSWVEFAFNSSPLTPYYRLYRICFMLRSLRLILIFQGLINIQRLMRVMVY 1639
Query: 1661 SLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAG 1720
+LP L I +L M +FA+FG + + +D+ NF Q+M+ LF+ ++
Sbjct: 1640 ALPFLGKIFFILIDTMLVFALFGCQLYGQIDSGQVMDEQINFHNIAQAMLTLFKCASGDD 1699
Query: 1721 WDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENY 1780
W ++ ++ N CGS T Y ++++S + +N+++ ++E +
Sbjct: 1700 WRTIMTDTMHHN-----PNCTNDSTYCGS-TYSQIYFFLFMLLSNYVFLNLFVLGLIEQF 1753
Query: 1781 SQATEDVQEGLTD---DDYDMYYEIWQRFDPD-GSQYIRYDQLSDFLDVLEPPL 1830
++ VQ + ++ D IW ++ P+ + + Y L FL L PL
Sbjct: 1754 -ESFFQVQNSIIQTYVENEDRIKTIWCKYSPETQGKAMHYKFLCRFLMDLGAPL 1806
Score = 66.5 bits (155), Expect = 7e-09
Identities = 61/272 (22%), Positives = 127/272 (46%), Gaps = 27/272 (9%)
Query: 143 FSLFIITTILVNCILMIMPTTPTVEST---EVIFTGIYTFESAVKVMARGFILQPFTYLR 199
F + + IL N L I+ T E T E I T ++ E ++++++GF+ Y
Sbjct: 215 FQILMTILILFNIALYIIVKTEHREDTDQIEQIITILFFTEIGLRILSQGFLFSKNAYFI 274
Query: 200 DAWNWLDFVVIALAYVTM---GIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESV 256
+ N DF ++ L+ + + I + +L+ LR +L+ L I GL+ ++ A+ +S+
Sbjct: 275 NFSNVFDFSIVLLSALNLYRPDIMIIDLSPLRIITLLQYLGD--IFDGLRVMLTALRQSI 332
Query: 257 KNLRDVI-ILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNET 315
K + + + I+ +FSL FAL GL ++ G+ +C+ P++ + + N ++ C +E
Sbjct: 333 KYILEALAIVGLFSL-FFALAGLYLFQGLFNYRCMPTNPDEDAGDDWIQCNVDQ-CPDEM 390
Query: 316 NWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDY 375
C + + + + + + D + W R+ +
Sbjct: 391 T----------CQYVANTVKVPTSFNNII-YSYGQILRTITMDDWSWVMFFTIRIFSPWV 439
Query: 376 WENLYQLFFVVIIFLGSFYLVNLILAIVAMSY 407
W +++++IIF+G F+ NL++A++ Y
Sbjct: 440 W-----IYYLLIIFVGGFFGFNLVIAVLKTHY 466
Score = 59.3 bits (137), Expect = 1e-06
Identities = 59/233 (25%), Positives = 107/233 (45%), Gaps = 24/233 (10%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
K I N+ ++T+++L ++AL + V HR I ++I T++FF E+ ++ L
Sbjct: 207 KTIVNSIGFQILMTILILFNIALYII-VKTEHREDTDQI----EQIITILFFTEIGLRIL 261
Query: 1273 ALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMS 1328
+ GF YF N DF IV++S +N + + + L+ L +
Sbjct: 262 SQGFLFSKNAYFINFSNVFDFSIVLLSALNLYRPDIMIIDLSPLRIITLLQYLGDI---- 317
Query: 1329 RMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKCVDMN------- 1380
G+RV++ AL Q+I I L + +F L FA+ G+ LF G + ++C+ N
Sbjct: 318 -FDGLRVMLTALRQSIKYILEALAIVGLFSLFFALAGLYLFQGLFNYRCMPTNPDEDAGD 376
Query: 1381 -HTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIM 1432
+ + PD+ C T P +F+++ +Y + + T W +M
Sbjct: 377 DWIQCNVDQCPDEMTCQYVANT-VKVPTSFNNIIYSYGQILRTITMDDWSWVM 428
Score = 47.2 bits (107), Expect = 0.005
Identities = 54/243 (22%), Positives = 104/243 (42%), Gaps = 38/243 (15%)
Query: 1251 ILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVA--------- 1301
I+ Y+ F++ I LI++LALG ++F N W FI+++ ++ + V
Sbjct: 1536 IINYIHHGFSITITIWGLIQYLALGLFRFFDNYWRQFLFILILFAITDLVIDFEFSWVEF 1595
Query: 1302 ALCGAGGIQAFKTMRTLRALRPLRAMSRMQGM---RVVVNALVQAIPSIFNVLLVCLIFW 1358
A + ++ R LR LR + QG+ + ++ +V A+P + + + +
Sbjct: 1596 AFNSSPLTPYYRLYRICFMLRSLRLILIFQGLINIQRLMRVMVYALPFLGKIFFILIDTM 1655
Query: 1359 LIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLC 1418
L+FA+ G QL+ +D S +++ ++ +NF ++ +A L
Sbjct: 1656 LVFALFGCQLYGQ-----ID------SGQVMDEQ--------------INFHNIAQAMLT 1690
Query: 1419 LFQVATFKGWIQIMNDAI-DSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVII 1477
LF+ A+ W IM D + + + Y +Y LNLF+ +I
Sbjct: 1691 LFKCASGDDWRTIMTDTMHHNPNCTNDSTYCGSTYSQIYFFLFMLLSNYVFLNLFVLGLI 1750
Query: 1478 DNF 1480
+ F
Sbjct: 1751 EQF 1753
Score = 44.0 bits (99), Expect = 0.042
Identities = 39/198 (19%), Positives = 89/198 (44%), Gaps = 8/198 (4%)
Query: 1529 VFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIF 1588
V +V+ K ++ + L I +N ++L + S V D I ++ S E L+
Sbjct: 853 VSRMVSSKITEIALDLLIFVNFTFLSLYGIVDASIISQVED----ITTILLSIETFLRYC 908
Query: 1589 ALRYHYFVEP-WNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKG 1647
+ + ++ ++V+ + + +SD + ++ LR++R K R +K
Sbjct: 909 SFSFKELSNSNESIMQTMIVILNFIEFTMSDYMPN--LTEQNLRLIRGTKCILFYRCLKY 966
Query: 1648 AKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGG-LDDVYNFKTFV 1706
T+ + + + L+F+V+F++A+ GM + D+ L ++++ +
Sbjct: 967 NSMAVTIGHIASKTFKQYIYLTFLMFIVIFLYALVGMEVYAGRFDQSDVLGQLHSYNNVL 1026
Query: 1707 QSMILLFQMSTSAGWDGV 1724
+S + +F + T+ W GV
Sbjct: 1027 KSFMTVFNIMTNDDWYGV 1044
Score = 41.5 bits (93), Expect = 0.23
Identities = 35/158 (22%), Positives = 70/158 (44%), Gaps = 11/158 (6%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR 1591
IV F +++ + I N+ + + E + + ++F L + F
Sbjct: 209 IVNSIGFQILMTILILFNIALYIIVKTEHREDTDQIEQIITILFFTEIGLRILSQGFLFS 268
Query: 1592 YH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAK-VGRVLRLVKGAK 1649
+ YF+ N+FDF +V+ S L+L DI+ + + LR++ + + +G +
Sbjct: 269 KNAYFINFSNVFDFSIVLLSALNLYRPDIM---IIDLSPLRIITLLQYLGDIF------D 319
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
G+R +L AL S+ + ++ L FA+ G+ F
Sbjct: 320 GLRVMLTALRQSIKYILEALAIVGLFSLFFALAGLYLF 357
>UniRef50_A1CQ08 Cluster: Calcium channel subunit Cch1; n=9;
Pezizomycotina|Rep: Calcium channel subunit Cch1 -
Aspergillus clavatus
Length = 2126
Score = 169 bits (411), Expect = 7e-40
Identities = 141/631 (22%), Positives = 283/631 (44%), Gaps = 36/631 (5%)
Query: 1217 NTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYM--DRIFTVIFFIEMLIKWLAL 1274
+ + A++ M+L++ + + H + + + I +Y+ D F ++F E LIK +A
Sbjct: 1200 SAFVYAAIVAMVLIACITTPIYQRHYQAQWVTKGIPWYVYTDMGFAILFTFEALIKVIAD 1259
Query: 1275 GF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGI-QAFKTMRTLRALRPLRAMSR 1329
GF YF ++W ++D I+++ IN ++L GI +A + LRALR L
Sbjct: 1260 GFFWTPNAYFRSSWGFIDGIVLVTLWINVGSSLFWDLGISRAIGAFKALRALRLLNVSDS 1319
Query: 1330 MQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEII 1389
+ + ++ + V + F + FAI GV L+ G+ C D + ++ I
Sbjct: 1320 AKD--TFHSVIIIGGWKVIAAAAVSMSFLIPFAIYGVTLYNGQMVTCNDGSIVGSLNQCI 1377
Query: 1390 PDKNACTLENYTWE-------NSPM-NFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREV 1441
N + Y WE ++P+ +FD+ G A LFQ+ + +GW + A+
Sbjct: 1378 ---NEYSSSPYNWEVLAPRAASNPLYDFDNFGNALFILFQIVSQEGWTDVQMSAMSITGK 1434
Query: 1442 GRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKK 1501
QP L+ L LF+ V + N+ EQ A F+T +Q+
Sbjct: 1435 DWQPQSFAAPANGLFFIVFNLLGAVFVLTLFVSVFMRNYTEQTGVA------FLTAEQRS 1488
Query: 1502 YYNAMKKMGSKKPLK-AIPRPRWRPQAIVFEIVTDK--KFDMIIMLFIGLNMLTMTLDHY 1558
+ K + P K ++ R + + + I K ++ + + L++L + L++Y
Sbjct: 1489 WLELRKLLRQISPSKRSLDRKSTKWKLWCYRIAVKKHGRWARCVTTILLLHLLLLILEYY 1548
Query: 1559 QQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEP-WNLFDFVVVMFSILSLVLS 1617
+ + + L F + + L+++F L +H F W+L+ + V + ++ +L+
Sbjct: 1549 PEPHLWELTRESLFFAFTFFYIANTLIRLFGLGWHRFSRSSWDLYSLIAVPGTFITTILN 1608
Query: 1618 DIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMF 1677
+++ + ++ + ++ V L L+ + L A SL A+ N+ F++
Sbjct: 1609 FLLK----NQVIMELNKLFLVSITLLLIPRNNQLDQLFKTAAASLTAIGNLLATWFVLFL 1664
Query: 1678 IFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLP 1737
+FAI F K ++ NF+ +++ILLF+MS GW+ +++
Sbjct: 1665 VFAIAMNQAFGLTKFGEHENNNINFRDIPRTLILLFRMSCGEGWNAIMEDFATMVPPFCT 1724
Query: 1738 DNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQ--EGLTDDD 1795
+ +CGSA +S+ +IS I +++++++I E++S + ++ ++
Sbjct: 1725 YDRDFFNDDCGSAAWARPLFISWNIISMYIFVSLFVSLIFESFSYVYQRSSGLYAISREE 1784
Query: 1796 YDMYYEIWQRFDPDGSQYIRYDQLSDFLDVL 1826
+ + W +DPDG+ YI +Q L L
Sbjct: 1785 IRRFKQAWATYDPDGTGYISKEQFPRLLGEL 1815
Score = 62.5 bits (145), Expect = 1e-07
Identities = 45/171 (26%), Positives = 80/171 (46%), Gaps = 11/171 (6%)
Query: 124 LDPFNPIR---RVAIYILVHPLFSLFIITTILVNCILMIMPTT---PTVESTEVIFTGIY 177
+DP+ P+ +Y + + + ITT + T P T++ F ++
Sbjct: 1189 VDPYKPVWYTFSAFVYAAIVAMVLIACITTPIYQRHYQAQWVTKGIPWYVYTDMGFAILF 1248
Query: 178 TFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI----DLGNLAALRTFRVL 233
TFE+ +KV+A GF P Y R +W ++D +V+ ++ +G DLG A+ F+ L
Sbjct: 1249 TFEALIKVIADGFFWTPNAYFRSSWGFIDGIVLVTLWINVGSSLFWDLGISRAIGAFKAL 1308
Query: 234 RALKTVAIVPGLK-TIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
RAL+ + + K T +I + ++M L FA+ G+ +Y G
Sbjct: 1309 RALRLLNVSDSAKDTFHSVIIIGGWKVIAAAAVSMSFLIPFAIYGVTLYNG 1359
Score = 56.0 bits (129), Expect = 1e-05
Identities = 28/100 (28%), Positives = 52/100 (52%)
Query: 1274 LGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGM 1333
L + + +++ LDF+ V+ ++F+ +L R L LR LR ++ G
Sbjct: 488 LAHRAFLRHSFNRLDFVAVVSFWVSFLLSLTSVENRHQLYVFRMLSCLRILRLLALTNGT 547
Query: 1334 RVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
V++ +L +A P + +V + FWL+FAI+G+Q F +
Sbjct: 548 SVILRSLKKAAPLLVHVAFLIGFFWLLFAIVGIQSFKSSF 587
Score = 53.6 bits (123), Expect = 5e-05
Identities = 59/239 (24%), Positives = 105/239 (43%), Gaps = 30/239 (12%)
Query: 197 YLRDAWNWLDFVVIALAYVTMGIDLG---NLAALRTFRVL---RALKTVAIVPGLKTIVG 250
+LR ++N LDFV + +V+ + L N L FR+L R L+ +A+ G I+
Sbjct: 493 FLRHSFNRLDFVAVVSFWVSFLLSLTSVENRHQLYVFRMLSCLRILRLLALTNGTSVILR 552
Query: 251 AVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWE-R 309
++ ++ L V L F +FA++G+Q + + C + + S +L D + +
Sbjct: 553 SLKKAAPLLVHVAFLIGFFWLLFAIVGIQSFKSSFRRSCRWLGRDGQSDFDLNDPSGTLQ 612
Query: 310 FCQNETN--------WY--GEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDT 359
FC N W G G+ G+ C G +C++ NP G +FD
Sbjct: 613 FCGGYLNATTGAKESWLKTGLNGELVSSGSEPKGYLCPQGSICVE--NTNPYEGTVNFDD 670
Query: 360 FGWAFLSAFRLMTQDYWENLY-----------QLFFVVIIFLGSFYLVNLILAIVAMSY 407
+ F +M+ + + +L LFF + S +LVNL++A++ S+
Sbjct: 671 IVHSLELVFVIMSSNTFTDLLYYTTNSDYLAAALFFACGFVILSLWLVNLLVAVITHSF 729
Score = 46.8 bits (106), Expect = 0.006
Identities = 35/155 (22%), Positives = 69/155 (44%), Gaps = 13/155 (8%)
Query: 1632 VVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVK 1691
V+ + ++ RV R+V R L+ + + L N+ + +FL+ F+ +IF F +
Sbjct: 858 VLTLFQILRVYRVVLAFSVTRNLIMVVFRNATGLLNLIMFVFLITFLASIFATQLF-RGQ 916
Query: 1692 DKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSAT 1751
D F S I ++Q+ +S W +L N +A
Sbjct: 917 TPDDEDAEITFADIYNSFIGMYQILSSENWTTIL------------YNSTTFTYKLHTAW 964
Query: 1752 IGITYLLSYLVISFLIVINMYIAVILENYSQATED 1786
I + + + +++ IV+NM+IAVI E++ + ++
Sbjct: 965 ISAIFFIIWFIVANFIVLNMFIAVIQESFDVSEDE 999
Score = 42.7 bits (96), Expect = 0.098
Identities = 30/93 (32%), Positives = 45/93 (48%), Gaps = 16/93 (17%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTE--------- 170
+L +L P NP+R ILVHP FI+ I++ IL+ + ++ +V+
Sbjct: 327 SLGVLGPDNPLRVRLCDILVHPFTEPFILVVIIIQTILLTIESSESVQDHPRSVRWGKDR 386
Query: 171 ------VIFTGIYTFESAVKVMARGFILQPFTY 197
VIF IYT E K++ GF+L P Y
Sbjct: 387 LDYAYLVIFI-IYTLELIAKILVSGFMLNPAEY 418
Score = 39.9 bits (89), Expect = 0.69
Identities = 21/115 (18%), Positives = 59/115 (51%), Gaps = 3/115 (2%)
Query: 1258 IFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRT 1317
I TV+ +E+++++ A ++ + + W+D +V+++ + + A+ G+G +++ +
Sbjct: 805 IVTVVLLVEIILRF-ASDWRVFHRSRRNWVDLGLVVITCVIQIPAIRGSG--RSYDVLTL 861
Query: 1318 LRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGK 1372
+ LR R + R ++ + + + N+++ + + +I QLF G+
Sbjct: 862 FQILRVYRVVLAFSVTRNLIMVVFRNATGLLNLIMFVFLITFLASIFATQLFRGQ 916
Score = 37.1 bits (82), Expect = 4.9
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 7/83 (8%)
Query: 845 LNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTD 904
L+ L ++ A+GNL ++ +FA+ Q FG + +F + + NF D
Sbjct: 1638 LDQLFKTAAASLTAIGNLLATWFVLFLVFAIAMNQAFG------LTKFGEHENNNINFRD 1691
Query: 905 FMHSFMIVFRVLCGE-WIESMWD 926
+ +++FR+ CGE W M D
Sbjct: 1692 IPRTLILLFRMSCGEGWNAIMED 1714
>UniRef50_A0D5W4 Cluster: Chromosome undetermined scaffold_39, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_39, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 2195
Score = 167 bits (405), Expect = 4e-39
Identities = 133/623 (21%), Positives = 284/623 (45%), Gaps = 52/623 (8%)
Query: 1206 TLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDI-LYYMDRIFTVIFF 1264
T + FK + N+ ++V TMI++S +L +H + + L+ ++ + T+ +
Sbjct: 1328 TTKSVIFKFVLNSSICSSVATMIIIS-FDDSLPSLHTNNLNTFYEYHLFAVNLVITITYI 1386
Query: 1265 IEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPL 1324
+E++ + + L + + W ++D + ++ ++F+ K L LRPL
Sbjct: 1387 LEIISQGMLLDQGAFCRDIWRFIDILYLISYYLSFMTLS------PFLKFSLYLIYLRPL 1440
Query: 1325 RAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTL 1384
++ Q ++ + NA+ ++ I N++ V L+ +LIF ++G+ L+ K C D+ + +
Sbjct: 1441 MMINMFQSIQGIKNAMSLSLVQILNIIGVILLVFLIFDVIGMHLYQNKMGYCEDLMNFYV 1500
Query: 1385 SHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSRE--VG 1442
+ + C+ +N TW P NF+++ L LF A+ GW +IM ++ + G
Sbjct: 1501 N------EFQCSQQNKTWVIHPYNFENILNGLLTLFLAASLDGWGEIMQVCFNANDSKYG 1554
Query: 1443 RQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKY 1502
P+ T YL+ + GV+ F + K+ ++T DQ ++
Sbjct: 1555 PTPLN-TQWATYLFFILFIFIGAMFFMGFLTGVLFTEFQKYTKQLENK---YLTSDQSQF 1610
Query: 1503 YNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSE 1562
+ + + P + P P+ + + ++IV + ++ + +N + + L + S
Sbjct: 1611 LKISELILQQSPGYSNP-PKTPLRRLCYKIVFSLWYHKFFIVVLCVNTIVLCLFYSDASY 1669
Query: 1563 TFSAVLDYLNMIFIVIFSSECLLKIFALR-YHYFVEPWNLFDFVVVMFSILSLVLSDI-- 1619
+ + L+ + +F+ + ++K+ A YF W + + + ++ +
Sbjct: 1670 EYMSNLNKTYQVLTGVFALDTIIKLLAYGPTRYFATNWRVIELSLSFIAVADFIYDSYWG 1729
Query: 1620 ----------IEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNIC 1669
+KYF T R++ + R+L +++ KG+ LL L S+P LF I
Sbjct: 1730 WFTTFLGANQSDKYF---TFYRILFCMRDIRILLIIQEFKGLLRLLRVLLFSMPLLFKIL 1786
Query: 1670 LLLFLVMFIFAIFGMSFFMHVKDKGGLDDVY-NFKTFVQSMILLFQMSTSAGWDGVLDGI 1728
+ + +A+ G F H+ + +DD Y NFK F+ S +L+F+ +T W +L
Sbjct: 1787 YIQVIAQTTYALIGKELFSHISNGSVIDDKYANFKNFINSALLMFKCTTGDDWRALL--- 1843
Query: 1729 INEEECDLPDNE--RGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVIL---ENYSQA 1783
+C P N R CGS + + LSY + S +I++N+++ ++ EN+ A
Sbjct: 1844 ---IDCS-PQNYYCRSDSNQCGSQW-SLPFFLSYYLFSNIIIMNLFVLALVDQFENFFNA 1898
Query: 1784 TEDVQEGLTDDDYDMYYEIWQRF 1806
+ + + ++ D + +W ++
Sbjct: 1899 STNAIQTFV-ENVDHFCNVWCKY 1920
Score = 61.7 bits (143), Expect = 2e-07
Identities = 45/199 (22%), Positives = 101/199 (50%), Gaps = 9/199 (4%)
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL 1590
+++ +K +I L+ +N + + Y S+ ++D +N + + E +LKI
Sbjct: 975 KLLEEKMVSIIFDLYTMVNFFILCSEGYLSSD----LVDSINSVMTFLLLGEIVLKIIGY 1030
Query: 1591 RYHYFVE-PWNLFDFVVVMFSILSLVLSDIIEKYFVSP--TLLRVVRVAKVGRVLRLVKG 1647
F + N D V++ +L +S I + Y++ + ++V+R +K + R++K
Sbjct: 1031 GIKDFSKMSSNNLDAFVIVLCLLQYFIS-ITQPYWLEQYSSEIKVLRASKAFMLYRVIKY 1089
Query: 1648 AKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKG-GLDDVYNFKTFV 1706
K + ++ +++ + NI L+F V+F++AI G+ FF++ D+ L +++F +
Sbjct: 1090 NKFVVRIMKIAQLTMKSYINITFLMFYVIFMYAIMGLQFFVNKFDESQRLAQLHSFNSIG 1149
Query: 1707 QSMILLFQMSTSAGWDGVL 1725
+S + +F T+ G+L
Sbjct: 1150 KSWMTVFNTITNDDAVGML 1168
Score = 60.5 bits (140), Expect = 5e-07
Identities = 62/250 (24%), Positives = 109/250 (43%), Gaps = 49/250 (19%)
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIAL--AYVTMGIDLGNLAALR 228
++F IY E +K++ G + + + WN D V + L Y+ + + + LR
Sbjct: 284 IVFFWIYVVEHGIKIVGLGLV----QFFKVFWNCYDLVNLILFGLYIYGSLSF-DFSPLR 338
Query: 229 TFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQK 288
R+L ++ I L+ + A+ ES+KN+ + ++ + FA +G+ ++ +L +
Sbjct: 339 AMRIL--IQLAKISSQLQKTLKALTESLKNMMEASLVVLIFCIFFANVGVHLFSQLLQNR 396
Query: 289 CVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGP 348
C + EDG + F QN W C N+ C Q
Sbjct: 397 CFYI--EDGI---------QDFNQNICGWVD-------CPNNMN---------CFQSL-- 427
Query: 349 NPNYGYTSFDTFGWAFLSAFRLMTQDYWEN-----LYQL------FFVVIIFLGSFYLVN 397
N T+FD F +AF R +T D W + +Y L +FV++IF+ F+ N
Sbjct: 428 NNVDTATNFDNFFFAFAQIIRTITMDNWTDVMYYTMYTLSPMTWIYFVLVIFIVGFFAFN 487
Query: 398 LILAIVAMSY 407
LI+A++ Y
Sbjct: 488 LIIAVLKTQY 497
Score = 48.8 bits (111), Expect = 0.001
Identities = 46/183 (25%), Positives = 81/183 (44%), Gaps = 16/183 (8%)
Query: 1258 IFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRT 1317
+F I+ +E IK + LG ++F W D +V+LI F + G+ F +R
Sbjct: 285 VFFWIYVVEHGIKIVGLGLVQFFKVFWNCYD----LVNLILFGLYIYGSLSFD-FSPLRA 339
Query: 1318 LRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG-KYFKC 1376
+R L L +S ++ + AL +++ ++ LV LIF + FA +GV LF+ +C
Sbjct: 340 MRILIQLAKISSQ--LQKTLKALTESLKNMMEASLVVLIFCIFFANVGVHLFSQLLQNRC 397
Query: 1377 V-------DMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWI 1429
D N P+ C ++ ++ NFD+ A+ + + T W
Sbjct: 398 FYIEDGIQDFNQNICGWVDCPNNMNC-FQSLNNVDTATNFDNFFFAFAQIIRTITMDNWT 456
Query: 1430 QIM 1432
+M
Sbjct: 457 DVM 459
Score = 37.9 bits (84), Expect = 2.8
Identities = 34/178 (19%), Positives = 83/178 (46%), Gaps = 10/178 (5%)
Query: 1200 FWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIF 1259
F+ W L+ K KL+E +++ L E + D++ ++ +
Sbjct: 962 FYGYWIVLQFKLHKLLEEKMVSIIFDLYTMVNFFILCSEGY------LSSDLVDSINSVM 1015
Query: 1260 TVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKT-MRTL 1318
T + E+++K + G + + + LD ++++ L+ + ++ ++ + + ++ L
Sbjct: 1016 TFLLLGEIVLKIIGYGIKDFSKMSSNNLDAFVIVLCLLQYFISITQPYWLEQYSSEIKVL 1075
Query: 1319 RALRPLRAMSRMQGMRVVVNALVQAIPSIFNVL-LVCLIFWLIF--AIMGVQLFAGKY 1373
RA + ++ + VV + A ++ + + + L+F++IF AIMG+Q F K+
Sbjct: 1076 RASKAFMLYRVIKYNKFVVRIMKIAQLTMKSYINITFLMFYVIFMYAIMGLQFFVNKF 1133
Score = 36.3 bits (80), Expect = 8.5
Identities = 16/57 (28%), Positives = 34/57 (59%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
K L++ ++++ K + ++ I TM + N+TF++ +IF++A+MG+Q F
Sbjct: 1073 KVLRASKAFMLYRVIKYNKFVVRIMKIAQLTMKSYINITFLMFYVIFMYAIMGLQFF 1129
>UniRef50_A0DXQ5 Cluster: Chromosome undetermined scaffold_69, whole
genome shotgun sequence; n=7; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_69, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 2127
Score = 165 bits (402), Expect = 8e-39
Identities = 144/624 (23%), Positives = 276/624 (44%), Gaps = 40/624 (6%)
Query: 1227 MILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGF----QKYFTN 1282
+IL +SL + + + + I + I + F+++LI +A G YF +
Sbjct: 1250 LILYASLITFIMNTYYDYEDTNNTICDQIQLIINIQMFLDILINIIAKGLFLDKGSYFVS 1309
Query: 1283 AWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQ 1342
W LD I ++ I F I F L LRP++ + R+ + + AL
Sbjct: 1310 VWQILDVIYIISHFITFNNPTDHYAKI--FDLCLYLGYLRPMKLLFRISWLTQLRIALGY 1367
Query: 1343 AIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTW 1402
++ I NVL+ L W++F + + L+ G++ C D + +++E C EN W
Sbjct: 1368 SLVDITNVLITMLAVWIMFGVYAIILYEGQFGFCEDKMNFNVNYE------QCIQENRNW 1421
Query: 1403 ENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSR--EVGRQPIRETNIYMYLYXXXX 1460
N NFD++ A LF +T GW +I A +S+ ++G Q + +Y Y +
Sbjct: 1422 INYKHNFDNITVAIPSLFVTSTLDGWGEIYQVAENSQSADIGPQAFN-SYVYTYFFFIIF 1480
Query: 1461 XXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPR 1520
L+LF GV+ N E ++K + E ++ QK++ + P+ + P
Sbjct: 1481 VFIGSMFFLSLFTGVLYSNLKENQQKIEMTDE---SQSQKEFQEISSIIIKDFPVFSSP- 1536
Query: 1521 PRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFS 1580
P + + +I + + LF+ L++ + L SE + ++ ++ F V++
Sbjct: 1537 PTKGMRKLASDITNNTYMLTCMYLFLILDLCILLLFESDMSEEYFRTVNNIHNTFTVLYV 1596
Query: 1581 SECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSLVLS---DIIEKYFVSPT------LL 1630
+L AL +F W F F +++ SI+ + D I Y+ S LL
Sbjct: 1597 IWVVLLFLALGVGRFFDNYWRRFYFFLIIVSIIDFIADYSVDWIMVYYKSTPHDSGYQLL 1656
Query: 1631 RVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHV 1690
R+ + RV+ + +G ++ L+ + +LP L I +L + M IFA+ G + +
Sbjct: 1657 RLFFSLRSLRVILIFQGLINLQRLMRVMVFALPFLGKIFTILMIAMLIFALIGCQLYGEI 1716
Query: 1691 KDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSA 1750
+DD NF+ Q+++ LF+ ++ W ++ + L D P CGS
Sbjct: 1717 DSGAVMDDQINFQNVAQALLALFKCASGDDWRTIMTDTMQHNPLCLED-----PKYCGSV 1771
Query: 1751 TIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTD---DDYDMYYEIWQRFD 1807
+ L ++++S +++N+++ ++E + Q + +Q L ++ D +W ++
Sbjct: 1772 NSQYFFFL-FMLLSNYVLLNLFVLGLIEQFEQFFQ-LQNSLIQTYVENVDKIKTVWCKYS 1829
Query: 1808 PD-GSQYIRYDQLSDFLDVLEPPL 1830
+ Q + Y L FL + PL
Sbjct: 1830 SETQGQAMNYKFLCKFLLDIGKPL 1853
Score = 54.8 bits (126), Expect = 2e-05
Identities = 53/220 (24%), Positives = 101/220 (45%), Gaps = 21/220 (9%)
Query: 1224 VITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGF----QKY 1279
++T+++L ++AL + V HR + + ++++ T++F IE+L++ GF +
Sbjct: 257 LMTILILFNVALFII-VKTQHR----EDTFQIEQVITILFIIEILVRIFVSGFFFTKNAF 311
Query: 1280 FTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNA 1339
F N DF ++ + IN I + + L L + G+ V++ A
Sbjct: 312 FRNIQDIYDFTLIFATTINLYYPDIFIIDISPLRMITLLFYLGDI-----FVGLGVMLLA 366
Query: 1340 LVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKCVDMNHTTLSHEIIPDKNACTLE 1398
L Q+I + L++ +F L FAI GV LF G + F+C N + ++N C +
Sbjct: 367 LKQSIKFLLEALMIVGLFSLFFAICGVFLFQGLFNFRCEYDNGDETDGWVQCNQNQCYED 426
Query: 1399 NYTWE------NSPMNFDHVGKAYLCLFQVATFKGWIQIM 1432
T + P +F++V +Y + + T W +M
Sbjct: 427 GMTCKYTEQTPKMPTSFNNVIYSYGQILRTITMDDWSWVM 466
Score = 54.4 bits (125), Expect = 3e-05
Identities = 44/198 (22%), Positives = 90/198 (45%), Gaps = 10/198 (5%)
Query: 1530 FEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFA 1589
+ I+T L I +N + L + S T +V + + +I S E +L++ +
Sbjct: 898 YRIITSSTSQTFFDLIIFINFTFLALWNIVNSNTIHSVEN----VSTIILSIELILRLIS 953
Query: 1590 LRYHYFVEPWN-LFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVK-G 1647
+ F N LF +V+ +I+ L + D++ + LR++R K R +K
Sbjct: 954 IPTKQFTSNPNFLFQAAIVILNIIELTIKDLL--IGLGEQNLRLIRGTKCLLFYRCLKYN 1011
Query: 1648 AKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF-MHVKDKGGLDDVYNFKTFV 1706
A ++ A +M+ + L+FLV+F++A+ GM + L ++++
Sbjct: 1012 AMAVKIGHIA-SMTFKQYIYLTFLMFLVIFMYALVGMEMYASEFSQTDSLGQLHSYDNIF 1070
Query: 1707 QSMILLFQMSTSAGWDGV 1724
++ + +F + T+ W GV
Sbjct: 1071 KAFMTIFNIMTNDDWYGV 1088
Score = 52.8 bits (121), Expect = 9e-05
Identities = 61/274 (22%), Positives = 121/274 (44%), Gaps = 30/274 (10%)
Query: 142 LFSLFIITTILVNCILMIMPTTPTVEST---EVIFTGIYTFESAVKVMARGFILQPFTYL 198
L+ + + IL N L I+ T E T E + T ++ E V++ GF +
Sbjct: 253 LYKILMTILILFNVALFIIVKTQHREDTFQIEQVITILFIIEILVRIFVSGFFFTKNAFF 312
Query: 199 RDAWNWLDFVVIALAYVTM---GIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIES 255
R+ + DF +I + + I + +++ LR +L L + + GL ++ A+ +S
Sbjct: 313 RNIQDIYDFTLIFATTINLYYPDIFIIDISPLRMITLLFYLGDIFV--GLGVMLLALKQS 370
Query: 256 VKNLRDVIILT-MFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNE 314
+K L + +++ +FSL FA+ G+ ++ G+ +C + G+ TD W + QN+
Sbjct: 371 IKFLLEALMIVGLFSL-FFAICGVFLFQGLFNFRC------EYDNGDETD-GWVQCNQNQ 422
Query: 315 TNWYGEGGDYPLCGNSSGAGQCEPGY-VCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQ 373
Y +G C + + + + +G + D + W R+
Sbjct: 423 C--YEDG---MTCKYTEQTPKMPTSFNNVIYSYG--QILRTITMDDWSWVMFFTMRIYHP 475
Query: 374 DYWENLYQLFFVVIIFLGSFYLVNLILAIVAMSY 407
W ++++ IIFL F+ NL++A++ Y
Sbjct: 476 QIW-----IYYLGIIFLCGFFGFNLVIAVLKTHY 504
>UniRef50_Q8IZF0 Cluster: Voltage gated channel-like protein 1; n=39;
Coelomata|Rep: Voltage gated channel-like protein 1 -
Homo sapiens (Human)
Length = 1738
Score = 165 bits (400), Expect = 1e-38
Identities = 169/646 (26%), Positives = 289/646 (44%), Gaps = 59/646 (9%)
Query: 1218 TYFETAVITMILLSSLALALEDV--HLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALG 1275
TY + +I + + S +++ E + H P LQ Y +F + IE+ +K +A G
Sbjct: 886 TYLDWVMIIVTICSCISMMFESPFRRVMHAPTLQIAEY----VFVIFMSIELNLKIMADG 941
Query: 1276 FQKYFTNAWCWLDF------IIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSR 1329
+FT DF I +VSLI + + LR LRPLR
Sbjct: 942 L--FFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAESGAQLLMVLRCLRPLRIFKL 999
Query: 1330 MQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMN--------- 1380
+ MR VV L IF V ++ L L+FA GVQLFAGK KC D N
Sbjct: 1000 VPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNG 1059
Query: 1381 --------HTTLSHEIIP-DKNACTLENYTWENSP-MNFDHVGKAYLCLFQVATFKGWIQ 1430
L+ ++ P +K W N NFD+VG A L LF+V + KGW++
Sbjct: 1060 IFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVE 1119
Query: 1431 IMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGS 1490
+ D I R VG PI I+++++ L LF+GV+I NFNE K A
Sbjct: 1120 V-RDVIIHR-VG--PIHGIYIHVFVFLGCMIG------LTLFVGVVIANFNENKGTA--- 1166
Query: 1491 LEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRP-QAIVFEIVTDKKFDMIIMLFIGLN 1549
+T DQ+++ + ++ +PL PRP +A +++I F I L +
Sbjct: 1167 ---LLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMYDITQHPFFKRTIALLVLAQ 1223
Query: 1550 MLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPW-NLFDFVVVM 1608
+ +++ + + + L ++++F IF E +KI A+ F + N +D +V
Sbjct: 1224 SVLLSVK-WDVEDPVTVPLATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRNRYDLLVTS 1282
Query: 1609 FSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNI 1668
++ +VL + + V+ V R + ++ LL + +S+ F I
Sbjct: 1283 LGVVWVVLHFALLNAYTYMMGACVI----VFRFFSICGKHVTLKMLLLTVVVSMYKSFFI 1338
Query: 1669 CLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGI 1728
+ +FL++ +A G+ F VK ++ NF + +++ +LF++ T W+ ++
Sbjct: 1339 IVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDC 1398
Query: 1729 INEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYS--QATED 1786
+ + PD +CG+ + Y S+ VI I++N+ +A+I+EN+S +TE+
Sbjct: 1399 MVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEE 1458
Query: 1787 VQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQI 1832
Q L+ +D + IW D I ++ L +L L++
Sbjct: 1459 DQL-LSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEV 1503
Score = 107 bits (258), Expect = 2e-21
Identities = 139/589 (23%), Positives = 254/589 (43%), Gaps = 84/589 (14%)
Query: 1244 HRPILQDILYYMDRIFTVIFFIEML----IKWLALGFQKYFTNAWCWLDFIIVMVSLINF 1299
H P LQ + + +D + ++ EM+ I+ + G Y + WC D +V ++
Sbjct: 63 HYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIVKGDSSYVKDRWCVFDGFMVFCLWVSL 122
Query: 1300 VAALCGAGGIQ-------AFKTMRTLRALRPLRAMSRMQGMRV-VVNALVQAIPSIFNVL 1351
V + I + R L +R R R + R + N L ++ I++V
Sbjct: 123 VLQVFEIADIVDQMSPWGMLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVS 182
Query: 1352 LVCLIFWLIFAIMGVQLFAGKYFKCVDMNHT-----TLSHEIIPDKNA------------ 1394
+ L F L++ I+GVQ+F + CV +N T T + IPD +
Sbjct: 183 IFLLFFLLLYGILGVQMFGTFTYHCV-VNDTKPGNVTWNSLAIPDTHCSPELEEGYQCPP 241
Query: 1395 ---CT-LENYTWENSPMN---FDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIR 1447
C LE+ + F+ +G + +++ A+ +GW+ +M AIDS R
Sbjct: 242 GFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRS--- 298
Query: 1448 ETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNE---QKKKAGGSLEMFMTEDQKKYYN 1504
Y Y N+FI VII+ F E Q ++ GS + + ++
Sbjct: 299 ------YFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFH 352
Query: 1505 AMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETF 1564
G + + +P+ R A + +++ F M I+ + ++++ ++Y+ E F
Sbjct: 353 EDAAGGWQLVAVDVNKPQGRAPACLQKMMRSSVFHMFILSMVTVDVIVAASNYYK-GENF 411
Query: 1565 SAVLD--YL-NMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDII 1620
D YL + F V+F E LLKI+ L + Y + F+ ++V+ + L V D+
Sbjct: 412 RRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLH-VYPDLY 470
Query: 1621 EKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFA 1680
F +LRVVR+ K+ L + +F L +L L +VM +
Sbjct: 471 HSQFTYFQVLRVVRLIKISPAL------EDFVYKIFGPGKKLGSLVVFTASLLIVM---S 521
Query: 1681 IFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNE 1740
+ F V++ LD F TF ++ + +FQ+ T GW V+D +N
Sbjct: 522 AISLQMFCFVEE---LD---RFTTFPRAFMSMFQILTQEGWVDVMDQTLN---------- 565
Query: 1741 RGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQE 1789
+ G+ + + I Y + Y + + LI++++++AVIL+N + ED+++
Sbjct: 566 --AVGHMWAPVVAI-YFILYHLFATLILLSLFVAVILDNL-ELDEDLKK 610
Score = 54.4 bits (125), Expect = 3e-05
Identities = 46/165 (27%), Positives = 76/165 (46%), Gaps = 15/165 (9%)
Query: 138 LVHPLFSLFIITTILVNCILMIMPT-------TPTVESTEVIFTGIYTFESAVKVMARGF 190
LV L + II TI +CI M+ + PT++ E +F + E +K+MA G
Sbjct: 884 LVTYLDWVMIIVTIC-SCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGL 942
Query: 191 ILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA------LRTFRVLRALKTVAIVPG 244
P +RD +D + ++ + + N+ A L R LR L+ +VP
Sbjct: 943 FFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAESGAQLLMVLRCLRPLRIFKLVPQ 1002
Query: 245 LKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKC 289
++ +V + K + V IL + + VFA G+Q++ G L KC
Sbjct: 1003 MRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLA-KC 1046
Score = 50.8 bits (116), Expect = 4e-04
Identities = 54/291 (18%), Positives = 121/291 (41%), Gaps = 25/291 (8%)
Query: 139 VHPLFSLFIITTILVNCILMIM------PTTPTVESTEVIFTGIYTFESAVKVMARGFIL 192
VH L + I +++ C+ M P + + + +YT E K+ RG +
Sbjct: 38 VHSLLRICAIISVISVCMNTPMTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIVK 97
Query: 193 QPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLA----ALRTFRVLRALKTVAIVPGLK-- 246
+Y++D W D ++ +V++ + + +A + + +LR + + ++ +
Sbjct: 98 GDSSYVKDRWCVFDGFMVFCLWVSLVLQVFEIADIVDQMSPWGMLRIPRPLIMIRAFRIY 157
Query: 247 --------TIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCV--KVFPED 296
I + S + + V I +F L ++ ++G+Q++ G T CV P +
Sbjct: 158 FRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMF-GTFTYHCVVNDTKPGN 216
Query: 297 GSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTS 356
+W +L + + E + G + G + E GY G + Y +
Sbjct: 217 VTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEA 276
Query: 357 FDTFGWAFLSAFRLMTQDYWENLYQLFFVVIIFLGSFYLVNLILAIVAMSY 407
GW FL + + W + + +F+ +IF ++ + N+ +A++ ++
Sbjct: 277 ASQEGWVFLMYRAIDSFPRWRSYF--YFITLIFFLAWLVKNVFIAVIIETF 325
Score = 40.3 bits (90), Expect = 0.52
Identities = 33/140 (23%), Positives = 63/140 (45%), Gaps = 7/140 (5%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRT 229
EV FT ++ E+ +K+ GF Y+ + + + +++ + + DL + +
Sbjct: 422 EVAFTVLFDLEALLKIWCLGFT----GYISSSLHKFELLLVIGTTLHVYPDLYH-SQFTY 476
Query: 230 FRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKC 289
F+VLR ++ + I P L+ V + K L +++ T L V + + LQ++ V
Sbjct: 477 FQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVEELDR 536
Query: 290 VKVFPED--GSWGNLTDENW 307
FP + LT E W
Sbjct: 537 FTTFPRAFMSMFQILTQEGW 556
>UniRef50_A7RTZ7 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1570
Score = 164 bits (399), Expect = 2e-38
Identities = 161/637 (25%), Positives = 287/637 (45%), Gaps = 52/637 (8%)
Query: 1218 TYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGF- 1276
TY E ++ + L S LA+ E + R + IF V +E+ ++ LA G
Sbjct: 856 TYLEWTMVFLTLASCLAMMTETPQV--RTFDNIATSAFEHIFVVGMSLELGVRILADGLV 913
Query: 1277 ---QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGM 1333
+ N LD +I ++SLI + + R LRPLR ++ M M
Sbjct: 914 FTPKAVIQNFGGALDIMIYLISLIYICWQPKSVPVNSGAQMLMIFRCLRPLRVLTLMPKM 973
Query: 1334 RVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH------- 1386
+ V+ LV I V + LI FAI GVQ+F+ + +C D + S
Sbjct: 974 KKVILELVGGYKEILKVSALQLILMFSFAIYGVQVFSRRLGRCSDPSIKLKSECKGLFYM 1033
Query: 1387 ------EI--IPDKNACTLENYTWENSPMNF--DHVGKAYLCLFQVATFKGWIQIMNDAI 1436
EI + K L W+N P NF D V +A+L LF+ + +GW++I D I
Sbjct: 1034 PLANPREIFTLNGKPPAMLVPRVWKN-PRNFSFDDVFQAFLALFEALSLEGWLEI-RDTI 1091
Query: 1437 DSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMT 1496
D VG E Y++ Y L LF+GV++ NFNE K A +T
Sbjct: 1092 DYA-VGP----EYGFYVHTYVLLGSMIG----LTLFVGVVVTNFNEHKGIA------LLT 1136
Query: 1497 EDQKKYYNAMKKMGSKKPLKAIPRPRWRP-QAIVFEIVTDKKFDMIIMLFIGLNMLTMTL 1555
DQ+++ + K++ +PL PRP + ++++V + ++ + + + T+ +
Sbjct: 1137 VDQRRWQDLKKRLRLAQPLHLPPRPDDNGIRKTLYDLVQSVIYRRVVAVVVLVECGTLAV 1196
Query: 1556 DHYQQSET-FSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILS 1613
+ +T V+ + ++F + +LK+ A Y+ N FD ++ ++
Sbjct: 1197 GQWTTVDTPVREVITSTAAVCTLLFVVDTILKLIAYTVRGYWHSRRNRFDLLLTSLGLIW 1256
Query: 1614 LVLSDII---EKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICL 1670
+VL+ + E ++ T+ VV + + R L L ++ L+ + MSL F
Sbjct: 1257 VVLNFSLKGNENAYLISTIFGVVII--IFRFLTLSGKHDMLKMLMLTVVMSLVKSFFTIA 1314
Query: 1671 LLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVL-DGII 1729
+L ++M +++ G+ F VK ++ NF T +MILLF+++T W+ ++ D ++
Sbjct: 1315 VLVILMMCYSLMGVILFGTVKYGEAINRYANFGTSFNAMILLFRVTTGEDWNKIMHDCMV 1374
Query: 1730 NEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQ-ATEDVQ 1788
E C +N S +CG+ T + Y +++ ++ I++N+++AVI+EN+S D
Sbjct: 1375 GEPYCTPEENFWES--DCGNYTASLIYFITFYIVVSFILLNVFVAVIIENFSLFYASDED 1432
Query: 1789 EGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDV 1825
L++ D + W D + Q F+ V
Sbjct: 1433 SLLSNTDLRDFQMAWNLVDKGRKGVMSVPQAKLFMRV 1469
Score = 81.0 bits (191), Expect = 3e-13
Identities = 113/602 (18%), Positives = 247/602 (41%), Gaps = 82/602 (13%)
Query: 1215 IENTYFETAVITMILLSSLALALEDVH-LPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
+++ +F+ + +LS +++A+ + P L + +D +F +EM+ +
Sbjct: 4 LKSWWFKRLIQVCSVLSLMSMAMNTPETFRNVPSLFYVTLVLDITLATVFTVEMIAQIRK 63
Query: 1274 LGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQA-----FKTMRTLRALRPL 1324
GF + Y C + ++++ +++ + L G + F R RAL
Sbjct: 64 FGFIVDLRAYLKRPQCIFNLSMLILIVLSIILQLVELTGYKPDPYIIFSIPRAPRALIMF 123
Query: 1325 RAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCV----DMN 1380
R R+ + I++V + L F + +I+GVQ+F K CV D++
Sbjct: 124 RVFKLFVNFRLDNEVSRRCRRQIWSVTIFFLYFMTLASIIGVQMFGSKNNYCVRNTTDLS 183
Query: 1381 HTTLSHEIIPDKNACTLENYTWENSPMNF-----------------DHVGKAYLCLFQVA 1423
+ T S ++P+ C++ N P NF DH + L ++ +
Sbjct: 184 NVTYSDLLLPEAR-CSISNEKGYICPANFYCAQINLDKFMAARRYFDHFFYSLLTVYTSS 242
Query: 1424 TFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQ 1483
T +GW+ +M ++ R + + + +Y N+FI V+ + F +
Sbjct: 243 TQEGWVLVMYQMMNVR---------SEVLVVIYFVLMMFFIAWLVKNVFIAVVSETFADV 293
Query: 1484 KKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAI--VFEIVTDKKFDMI 1541
+ + S +K G+ L ++ + A + IV +
Sbjct: 294 RSQYSKSRSSSRRRYTGLSSLVIKDQGAGWHLVSVDHEASKGHAPLPIRNIVASRYACWF 353
Query: 1542 IMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNL 1601
I + ++ L + + + +F ++F E L+KI+ + + ++ +
Sbjct: 354 IWFAVLVDALIQANNGSWRRQA--------QFVFTILFDIEALIKIWCVGFRTYLNSSRM 405
Query: 1602 --FDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVA--KVGRVLRLVKGAKGIRTLLFA 1657
F+F++ + S + F P L+ + +A V RV+RL+ G++
Sbjct: 406 QFFEFILAVGSTV-----------FALPVLMSIDALAIFHVMRVIRLIAAIPGLQDFCLK 454
Query: 1658 LAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMST 1717
+ + L ++ L + + + M F+ + D+ G + F T++ S+ +FQ+ T
Sbjct: 455 IFGTGKKLGSVILFTLFFVMVSSAISMQLFLTLSDRSG---IKIFGTYLTSLSSMFQIFT 511
Query: 1718 SAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVIL 1777
GW +++ + E G+A + I +L++Y + S LI++++++AVI+
Sbjct: 512 QDGWVVIVEKAMTSAEV------------YGAAVVAI-FLIAYHLFSSLIIMSVFVAVIV 558
Query: 1778 EN 1779
+N
Sbjct: 559 DN 560
Score = 54.4 bits (125), Expect = 3e-05
Identities = 31/125 (24%), Positives = 67/125 (53%), Gaps = 5/125 (4%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDA-WNWLDFVVIALAYVTMGIDLGNLAALR 228
+ +FT ++ E+ +K+ GF TYL + + +F++ + V L ++ AL
Sbjct: 376 QFVFTILFDIEALIKIWCVGFR----TYLNSSRMQFFEFILAVGSTVFALPVLMSIDALA 431
Query: 229 TFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQK 288
F V+R ++ +A +PGL+ + + K L VI+ T+F + V + + +Q+++ + +
Sbjct: 432 IFHVMRVIRLIAAIPGLQDFCLKIFGTGKKLGSVILFTLFFVMVSSAISMQLFLTLSDRS 491
Query: 289 CVKVF 293
+K+F
Sbjct: 492 GIKIF 496
Score = 46.8 bits (106), Expect = 0.006
Identities = 35/144 (24%), Positives = 71/144 (49%), Gaps = 15/144 (10%)
Query: 152 LVNCILMIMPTTPTVESTEVIFTGIY--------TFESAVKVMARGFILQPFTYLRDAWN 203
L +C+ M M TP V + + I T + + E V+++A G + P +++
Sbjct: 867 LASCLAM-MTETPQVRTFDNIATSAFEHIFVVGMSLELGVRILADGLVFTPKAVIQNFGG 925
Query: 204 WLDFVV--IALAYVTM---GIDLGNLAA-LRTFRVLRALKTVAIVPGLKTIVGAVIESVK 257
LD ++ I+L Y+ + + + A L FR LR L+ + ++P +K ++ ++ K
Sbjct: 926 ALDIMIYLISLIYICWQPKSVPVNSGAQMLMIFRCLRPLRVLTLMPKMKKVILELVGGYK 985
Query: 258 NLRDVIILTMFSLSVFALMGLQIY 281
+ V L + + FA+ G+Q++
Sbjct: 986 EILKVSALQLILMFSFAIYGVQVF 1009
Score = 40.7 bits (91), Expect = 0.40
Identities = 26/75 (34%), Positives = 43/75 (57%), Gaps = 10/75 (13%)
Query: 865 VLCIIIFIFAVMGMQLFGK-NYVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIE 922
VL I++ +++MG+ LFG Y + ++R+ NF ++ +++FRV GE W +
Sbjct: 1315 VLVILMMCYSLMGVILFGTVKYGEAINRYA-------NFGTSFNAMILLFRVTTGEDWNK 1367
Query: 923 SMWDCMLVGDVSCIP 937
M DCM VG+ C P
Sbjct: 1368 IMHDCM-VGEPYCTP 1381
>UniRef50_A0D437 Cluster: Chromosome undetermined scaffold_37, whole
genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_37, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 1601
Score = 164 bits (399), Expect = 2e-38
Identities = 124/584 (21%), Positives = 268/584 (45%), Gaps = 26/584 (4%)
Query: 1250 DILYYM-DRIFTVIFFIEMLIKWLALGFQKYFTNAWC-WLDFIIVMVSLINFVAALCGAG 1307
DILY + ++ + F+ ++ L + T ++ L+F+I ++ ++ V
Sbjct: 893 DILYIIITSLYCLFIFLHIVAHGLYGNSNAFLTQSFYNVLNFVITIIEIV--VVTTSTRN 950
Query: 1308 GIQAFKTMRTLRALRPLRAMSRM-QGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGV 1366
+ F + +LR ++ + + ++ ALV A+ + + + C I +L++ +
Sbjct: 951 HVINF--ISSLRVFEFIKLGAEIAHSIKYAQIALVNALVKMVQLSIFCFILFLVYGTFAM 1008
Query: 1367 QLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFK 1426
+L G + C +++ + C +W+ + FD++ + L LF V T +
Sbjct: 1009 KLLKGYNYYCTEVDQ---EENQVHSNIDCMDYGGSWQKHRLGFDNILDSALTLFVVVTSE 1065
Query: 1427 GWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
GW IM R P N Y +Y LN+FIG+++ ++E K K
Sbjct: 1066 GWSPIMEQIWSIRGENHTPEENYNRYWAIYFQVFFFIGNTCMLNMFIGLVVSTYDESKLK 1125
Query: 1487 AGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFI 1546
A G+ E + +Q+++++ K + +P RP+ + I F +V + I ++ I
Sbjct: 1126 AEGTFE--LEGNQREWFDIKKSIHKLQPKVKSRRPKAFFRKIAFFLVKNVNLKKIYLVVI 1183
Query: 1547 GLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFV 1605
+N L+++L + Q + L+ +N + I+IF E + + A + Y E N+ + +
Sbjct: 1184 FINTLSLSLCYENQDAQYKNSLEIINFVCILIFIFEIVSRFIAKDFKIYIKELINIIEII 1243
Query: 1606 VVMFSILSLVLSDI--IEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLP 1663
+ ++ ++ DI I +++ S + ++ R R++K I L ++ +P
Sbjct: 1244 GIWICLVEKII-DIKEIGEFYFSRCFKALSVAIQMLRNFRIIKRFNQIERLFHSIFSVIP 1302
Query: 1664 ALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDV-YNFKTFVQSMILLFQMSTSAGWD 1722
++ ++F+ +FI+ G+ F +++ + +DD +F+ F +M L ++++S W
Sbjct: 1303 NALSMLYIMFVFLFIYTSLGIDIFCYLRPQKYIDDFDVHFRKFTTAMFSLVRVASSELWW 1362
Query: 1723 GVLDGIINEEECDLP----DNERG----SPGNCGSATIGITYLLSYLVISFLIVINMYIA 1774
+L ++ D DN + CG+ TI Y +++ +I L+++N++IA
Sbjct: 1363 ELLVDALHTRSPDFACIEIDNYQDFLVYGYNGCGT-TIAYIYFITFHLIFSLVLLNLFIA 1421
Query: 1775 VILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQ 1818
IL Y + + Q ++ + W +DP G+ ++ Y Q
Sbjct: 1422 SILGAYEEHAKQEQNAISKYQLNDVLSYWVEYDPYGTGFLNYKQ 1465
Score = 98.7 bits (235), Expect = 1e-18
Identities = 58/196 (29%), Positives = 99/196 (50%), Gaps = 2/196 (1%)
Query: 106 ISKGKDIFRFSATNALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPT 165
I + K +FSA L++ +P RR L + S FII ++N + +P +
Sbjct: 67 IDENKQPGQFSAKKTLFLFKIDDPFRRSVTSFLNNKALSNFIILITILNIVAYSLPQSKI 126
Query: 166 VESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAY-VTMGIDLGNL 224
EV+ + E ++V+++G + + TYL+D WN + F+ + V + DL L
Sbjct: 127 SIGIEVVCNIFFGIEIILRVISQGLLFEENTYLKDKWNCIHFISFISGWLVLIDFDLIGL 186
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
L++ R+LR ++ + LK + A I S L VI+ +F L F+++GL +MG+
Sbjct: 187 KILKSIRLLRVIRLPEEISPLKNQLEAYISSFSKLGIVIVPFIFFLLYFSVIGLHFFMGL 246
Query: 285 LTQKC-VKVFPEDGSW 299
T +C + PEDG W
Sbjct: 247 TTMRCRLTPAPEDGKW 262
Score = 46.0 bits (104), Expect = 0.011
Identities = 34/161 (21%), Positives = 78/161 (48%), Gaps = 10/161 (6%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
+L E+ YF +I+L +L++ ++ + +++ L ++ T+ F+ E+ I +
Sbjct: 452 ELSESIYFAFLNNLVIILCTLSIVIDYDGIDKSILVK--LQIIEFACTLYFYFELSIFFF 509
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFV--------AALCGAGGIQAFKTMRTLRALRPL 1324
A G Q +F + +LDFI +M +I F + IQ FK ++ +R ++
Sbjct: 510 AKGIQNFFKKSVNYLDFIAIMSQIILFCILYFLDENVIINENRTIQVFKAIKLIRVIKFS 569
Query: 1325 RAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMG 1365
+ + ++ A +Q I + +++ + +I + A++G
Sbjct: 570 YSAKVFYHISILTRAAIQTIAKLKSIISLWIILAIFLALVG 610
>UniRef50_Q4P355 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 2263
Score = 164 bits (398), Expect = 3e-38
Identities = 143/600 (23%), Positives = 269/600 (44%), Gaps = 39/600 (6%)
Query: 1255 MDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKT 1314
+ +F F ++ + LA Y + W LD ++ LIN + L GG+ F
Sbjct: 1364 LSSLFLAEFMVKTIADGLAFTPNAYVLSIWNSLDLFVLTTLLINVITELAVIGGVSRF-- 1421
Query: 1315 MRTLRALRPLRAMSRMQGMRVVVNA-LVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
R L+A R LR ++ MR +A ++ I + ++ +++ + +AI G LFAG
Sbjct: 1422 TRALKAFRALRLINLSSLMRDTFHAVMIAGAGRILDASILSILYIIPYAIWGQNLFAGLL 1481
Query: 1374 FKCVDMNHTTLS------HEIIPDKNACTLENYTW----ENSPMNFDHVGKAYLCLFQVA 1423
+ C D +++ + I N L W E S +FD A L LF++
Sbjct: 1482 YSCNDTSNSIQTKFDCWGEYITSPGNFDFLAPRVWGNPTEGSVYSFDDFKGAMLILFEII 1541
Query: 1424 TFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQ 1483
+ +GWI +M+ A+ +Q + L+ L LF+ VII+NF
Sbjct: 1542 SLEGWIDVMSTAMGVAGKDQQLQNDNRQVNALFFLIYNLVGSTTVLTLFVSVIIENFQTF 1601
Query: 1484 KKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRP-QAI---VFEIVTDKK-- 1537
A F T Q+++ + + + ++P K RP+ RP QA+ ++ + +K
Sbjct: 1602 SGAA------FQTAGQRQWVDLRRLILRQRPSK---RPKHRPSQAVRAWCYDRMLNKNGW 1652
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVE 1597
+ + L ++T+ Y + + D L + + I++ + + ++ L + + E
Sbjct: 1653 WSRTMTLVYLSTLVTLMTQQYSDPAWANQLRDALYLGYTAIYALDIVARLLGLGWRSYRE 1712
Query: 1598 -PWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLF 1656
PWNL+D VV ++ + + ++ S +++ ++ L+LV+ + L
Sbjct: 1713 NPWNLYDLFVVSGTLATTL--PLLTGSGDSSVVVQFQKLFLTCVALKLVQKNHALNQLFK 1770
Query: 1657 ALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVY--NFKTFVQSMILLFQ 1714
SLPA+ ++ LL + ++AI + F K G ++ Y NF TF++SM+ L
Sbjct: 1771 TAFASLPAILSLFLLWLTMFLVWAIMLLEVF--GLTKWGPNETYSKNFSTFIRSMVFLSM 1828
Query: 1715 MSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYI 1773
+ST GW+ + D ++ +C + + +CGS +S+ VIS I +NM+
Sbjct: 1829 ISTGEGWNSFMHDYTLSPPQCTPAASYLMT--DCGSEPWAYALFISWNVISMYIFLNMFT 1886
Query: 1774 AVILENYSQATEDVQEG-LTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQI 1832
++EN+S + + LT D + W + D YI+ Q+ FL ++ L++
Sbjct: 1887 GTVVENFSYIFDLGSKAILTPSDIRYFKSSWAQVDRQRKGYIQKHQIVPFLASVKGALEV 1946
Score = 66.5 bits (155), Expect = 7e-09
Identities = 57/235 (24%), Positives = 103/235 (43%), Gaps = 27/235 (11%)
Query: 197 YLRDAWNWLDFVVIALAYVTMGIDLG--------NLAALRTFRVLRALKTVAIVPGLKTI 248
+LR +WN +D V + ++ + LG ++ R VLR + + G TI
Sbjct: 554 FLRHSWNRVDVVAVVAFWIAFALALGGQESANHHHIYIFRALSVLRCARLLTATSGTTTI 613
Query: 249 VGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWE 308
+ ++ S L V T +++ +F ++G+Q + G + CV V +G GN +
Sbjct: 614 LHSLKASAFILLSVTFFTGYAMLLFGIIGIQSFEGSYRRNCVWVGDLNGQPGN--NNTLS 671
Query: 309 RFCQNETNWYGEG-GDYPLCGNSSGAGQ----CEPGYVCLQGFGPNPNYGYTSFDTFGWA 363
+ C G+ G + G SG+ C G VC Q NP SFD +
Sbjct: 672 QLCGGYLTTAGQTLGHVLVDGAPSGSSPKGFICPRGQVC-QEQSTNPESNTQSFDNIITS 730
Query: 364 FLSAFRLMTQDYW-ENLYQ----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
L +++ + W + +Y ++F+V I + +F+L NL +A++ S+
Sbjct: 731 LLQVVIVISSNNWSQTMYDMIDADYYSSCIYFIVGIIILNFWLANLFVAVITNSF 785
Score = 54.8 bits (126), Expect = 2e-05
Identities = 111/540 (20%), Positives = 201/540 (37%), Gaps = 50/540 (9%)
Query: 1279 YFTNAWCWLDFIIVMVSLINFVAALCG--AGGIQAFKTMRTLRALRPLRAMSRMQGMRVV 1336
+ ++W +D + V+ I F AL G + R L LR R ++ G +
Sbjct: 554 FLRHSWNRVDVVAVVAFWIAFALALGGQESANHHHIYIFRALSVLRCARLLTATSGTTTI 613
Query: 1337 VNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK-CV---DM-----NHTTLSHE 1387
+++L + + +V L+F I+G+Q F G Y + CV D+ N+ TLS
Sbjct: 614 LHSLKASAFILLSVTFFTGYAMLLFGIIGIQSFEGSYRRNCVWVGDLNGQPGNNNTLSQL 673
Query: 1388 I--IPDKNACTLENYTWENSPMNFDHVG----KAYLCLFQVATFKGWIQIMNDAIDSREV 1441
TL + + +P G + +C Q + Q ++ I S
Sbjct: 674 CGGYLTTAGQTLGHVLVDGAPSGSSPKGFICPRGQVCQEQSTNPESNTQSFDNIITSLLQ 733
Query: 1442 GRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNF---NEQKKKAGGSLEMFMTED 1498
I N +Y + +G+II NF N S
Sbjct: 734 VVIVISSNNWSQTMY-DMIDADYYSSCIYFIVGIIILNFWLANLFVAVITNSFATLTART 792
Query: 1499 QKK-YYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTD-KKFDMIIMLFIGLNMLTMTLD 1556
Q+ + + + + S K + + R + A+ F+ V K+ I+ + +
Sbjct: 793 QRSAFADQILQDNSNKDQTQLQKGRLKSLALGFKRVWGYTKYLWILAIIFDVATQASRAT 852
Query: 1557 HYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-----YFVEPWNLFDFVVVMFSI 1611
+ Q +E + + F + F E ++ A + N DF + + +
Sbjct: 853 YLQPAEIQKRA--RIELYFTLAFDFEIAMRFLAFVLDGDWRGFLASKQNRADFFLAL--V 908
Query: 1612 LSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLL 1671
SL+ +I+ V P L ++ R R++ +R LL SL + N+ L
Sbjct: 909 TSLIQIPVIKSSQVYPWL----TFFQLARFYRVIAAIPRMRVLLVRAFGSLNKMLNMVLF 964
Query: 1672 LFLVMFIFAIFGMSFFMH--VKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGII 1729
L L++ + ++ F + G FK S + ++Q+ TS W VL
Sbjct: 965 LLLIVGLASLIATQLFRGDIPQQSDGQWTEMTFKHSFNSFLAMYQIFTSENWTDVLFSAT 1024
Query: 1730 NEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQE 1789
+ E A I +L + + + IV+ M+IAVI EN+S A + ++
Sbjct: 1025 SNEV------------EYKQAVIAAIFLSGWFLFANFIVLQMFIAVINENFSVAEHEKRQ 1072
Score = 47.6 bits (108), Expect = 0.003
Identities = 29/123 (23%), Positives = 61/123 (49%), Gaps = 4/123 (3%)
Query: 1248 LQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAG 1307
L+D LY +T I+ ++++ + L LG++ Y N W D +V +L + L G+G
Sbjct: 1682 LRDALYLG---YTAIYALDIVARLLGLGWRSYRENPWNLYDLFVVSGTLATTLPLLTGSG 1738
Query: 1308 GIQAFKTMRTL-RALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGV 1366
+ L L+ + + + + ++P+I ++ L+ L +L++AIM +
Sbjct: 1739 DSSVVVQFQKLFLTCVALKLVQKNHALNQLFKTAFASLPAILSLFLLWLTMFLVWAIMLL 1798
Query: 1367 QLF 1369
++F
Sbjct: 1799 EVF 1801
>UniRef50_Q9VY40 Cluster: CG1517-PB, isoform B; n=12; Coelomata|Rep:
CG1517-PB, isoform B - Drosophila melanogaster (Fruit
fly)
Length = 2196
Score = 163 bits (395), Expect = 6e-38
Identities = 151/616 (24%), Positives = 279/616 (45%), Gaps = 51/616 (8%)
Query: 1218 TYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGF- 1276
TY + +I LS +++ E + +R + L + F + +E+ +K LA G
Sbjct: 1186 TYLDWVMIFATTLSCISMMFETPN--YRVMDHPTLQIAEYGFVIFMSLELALKILADGLF 1243
Query: 1277 ---QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGM 1333
+ Y + LD I +VS A + + LR +RPLR + + M
Sbjct: 1244 FTPKAYIKDVAAALDVFIYVVSTSFLCWMPLNIPTNSAAQLLMILRCVRPLRIFTLVPHM 1303
Query: 1334 RVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD-------------MN 1380
R VV L + I V + ++ IFA GVQL+ G+ +C D M
Sbjct: 1304 RKVVYELCRGFKEILLVSTLLILLMFIFASYGVQLYGGRLARCNDPTISRREDCVGVFMR 1363
Query: 1381 HTTLSHEII---PDKN-ACTLENYTWENSP-MNFDHVGKAYLCLFQVATFKGWIQIMNDA 1435
++ + PD++ L W N NFD++G A L LF+V +FKGW+ + +
Sbjct: 1364 RVFVTKMKLTPGPDESYPAMLVPRVWANPRRFNFDNIGDAMLTLFEVLSFKGWLDVRDVL 1423
Query: 1436 IDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFM 1495
I + VG P+ I++Y++ L LF+GV+I N++E K A +
Sbjct: 1424 I--KAVG--PVHAVYIHIYIFLGCMIG------LTLFVGVVIANYSENKGTA------LL 1467
Query: 1496 TEDQKKYYNAMKKMGSKKPLKAIPRPRWRP-QAIVFEIVTDKKFDMIIMLFIGLNMLTMT 1554
T DQ+++ + K++ +PL PRP R +A ++I F +I + + +N + ++
Sbjct: 1468 TVDQRRWCDLKKRLKIAQPLHLPPRPDGRKIRAFTYDITQHIIFKRVIAVVVLINSMLLS 1527
Query: 1555 LDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILS 1613
+ + + E + L ++ + +F E ++K A Y+ N +D +V + ++
Sbjct: 1528 IT-WIKGEVHTERLVIVSAVLTFVFVVEVVMKNIAFTPRGYWQSRRNRYDLLVTVAGVIW 1586
Query: 1614 LVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLF 1673
++L I+ VV + R + ++ L+ + +S+ F I +F
Sbjct: 1587 IILQTILRNDLSYFFGFMVV----ILRFFTITGKHTTLKMLMLTVGVSVCKSFFIIFGMF 1642
Query: 1674 LVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVL-DGIINEE 1732
L++F +A+ G F VK G+ NF + V + +LF++ T W+ ++ D ++
Sbjct: 1643 LLVFFYALAGTILFGTVKYGEGIGRRANFGSPVTGVAMLFRIVTGEDWNKIMHDCMVQPP 1702
Query: 1733 ECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLT 1792
C L +N + +CG+ T + Y ++ VI IV+N+ +A+I+EN+S + ++ L
Sbjct: 1703 YCTLGNNYWET--DCGNFTASLIYFCTFYVIITYIVLNLLVAIIMENFSLFYSNEEDALL 1760
Query: 1793 D-DDYDMYYEIWQRFD 1807
D + W D
Sbjct: 1761 SYADIRNFQNTWNIVD 1776
Score = 63.7 bits (148), Expect = 5e-08
Identities = 108/481 (22%), Positives = 204/481 (42%), Gaps = 82/481 (17%)
Query: 1347 IFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHT----------TLSHEIIPDKNACT 1396
I+NV L L F ++ ++GVQ F CV MN+T T++ IPD C+
Sbjct: 461 IYNVTLFFLFFMSLYGLLGVQFFGELKNHCV-MNNTEYDLYKRPILTINSLAIPD-TFCS 518
Query: 1397 LE-NYTWENSP-----------------MNFDHVGKAYLCLFQVATFKGWIQIMNDAIDS 1438
++ + ++ SP F+ + + ++Q A+ +GW+ IM AIDS
Sbjct: 519 MDPDSGYQCSPGMVCMKMDFLSSYVIGFNGFEDIATSIFTVYQAASQEGWVFIMYRAIDS 578
Query: 1439 REVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNE---QKKKAGGSLEMFM 1495
R + + +L N+FI VI + FNE Q ++ G+
Sbjct: 579 LPAWRAAFYFSTMIFFL---------AWLVKNVFIAVITETFNEIRVQFQQMWGARGHIQ 629
Query: 1496 TEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFI---GLNMLT 1552
+ + + P+ I+ F M++M I G+ T
Sbjct: 630 KTAASQILSGNDTGWRLVTIDDNKHGGLAPETC-HAILRSPYFRMLVMSVILANGIVTAT 688
Query: 1553 MTLDHY-QQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFS 1610
MT H + + F Y+ ++F + E L KI+ L + Y+ + F+ ++ +
Sbjct: 689 MTFKHDGRPRDVFYERYYYIELVFTCLLDLETLFKIYCLGWRGYYKHSIHKFELLLAAGT 748
Query: 1611 ILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPAL--FNI 1668
L I+ ++ P+ L +V +V R+++ +G +F L +L F +
Sbjct: 749 TLH-----IVPMFY--PSGLTYFQVLRVVRLIKASPMLEGFVYKIFGPGKKLGSLIIFTM 801
Query: 1669 CLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGI 1728
CLL+ I + M F L D F++F ++ + +FQ+ T W V+D
Sbjct: 802 CLLI-----ISSSISMQLFCF------LCDFTKFESFPEAFMSMFQILTQEAWVEVMD-- 848
Query: 1729 INEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQ 1788
E + ++ +P + + ++L +L ++ LIV+++++AVIL+N + ED++
Sbjct: 849 ----ETMIRTSKTLTP------LVAVYFILYHLFVT-LIVLSLFVAVILDNL-ELDEDIK 896
Query: 1789 E 1789
+
Sbjct: 897 K 897
Score = 52.4 bits (120), Expect = 1e-04
Identities = 45/163 (27%), Positives = 76/163 (46%), Gaps = 14/163 (8%)
Query: 138 LVHPLFSLFIITTILVNCILMIMPTT-------PTVESTEVIFTGIYTFESAVKVMARGF 190
LV L + I T L +CI M+ T PT++ E F + E A+K++A G
Sbjct: 1184 LVTYLDWVMIFATTL-SCISMMFETPNYRVMDHPTLQIAEYGFVIFMSLELALKILADGL 1242
Query: 191 ILQPFTYLRDAWNWLD-FVVIA----LAYVTMGIDLGNLAAL-RTFRVLRALKTVAIVPG 244
P Y++D LD F+ + L ++ + I + A L R +R L+ +VP
Sbjct: 1243 FFTPKAYIKDVAAALDVFIYVVSTSFLCWMPLNIPTNSAAQLLMILRCVRPLRIFTLVPH 1302
Query: 245 LKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQ 287
++ +V + K + V L + + +FA G+Q+Y G L +
Sbjct: 1303 MRKVVYELCRGFKEILLVSTLLILLMFIFASYGVQLYGGRLAR 1345
Score = 43.6 bits (98), Expect = 0.056
Identities = 32/158 (20%), Positives = 76/158 (48%), Gaps = 9/158 (5%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRP--ILQDILYYMDRIFTVIFFIEMLIKW 1271
++ + YF V+++IL + + A RP + + YY++ +FT + +E L K
Sbjct: 665 ILRSPYFRMLVMSVILANGIVTATMTFKHDGRPRDVFYERYYYIELVFTCLLDLETLFKI 724
Query: 1272 LALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQ 1331
LG++ Y+ ++ + ++ + ++ V +G + LR +R ++A ++
Sbjct: 725 YCLGWRGYYKHSIHKFELLLAAGTTLHIVPMFYPSG----LTYFQVLRVVRLIKASPMLE 780
Query: 1332 GMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
G + + + S+ + +CL+ +I + + +QLF
Sbjct: 781 GFVYKIFGPGKKLGSLI-IFTMCLL--IISSSISMQLF 815
Score = 39.9 bits (89), Expect = 0.69
Identities = 27/98 (27%), Positives = 50/98 (51%), Gaps = 7/98 (7%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LR F + TL +L+ +G ++ + F + +++F +A+ G LFG ++
Sbjct: 1608 LRFFTITGKHTTLKMLMLTVGVSVCKSFFIIFGMFLLVFFYALAGTILFG------TVKY 1661
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCML 929
+G R NF + ++FR++ GE W + M DCM+
Sbjct: 1662 GEGIGRRANFGSPVTGVAMLFRIVTGEDWNKIMHDCMV 1699
>UniRef50_A0DX61 Cluster: Chromosome undetermined scaffold_68, whole
genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_68, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 2432
Score = 163 bits (395), Expect = 6e-38
Identities = 141/591 (23%), Positives = 266/591 (45%), Gaps = 43/591 (7%)
Query: 1261 VIFFIEMLIKWLALGFQKY---FTNA-WCWLDFIIVMVSLINFVAALCGAGGIQAFKTMR 1316
VI I+ ++K ++LGF + FT+ W +DFI + N + AFK ++
Sbjct: 1542 VILLIDSILKIISLGFTQEKGAFTSEFWRLIDFIYQLCYFANCILHY------SAFKYVK 1595
Query: 1317 TLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKC 1376
L+ RP R + + ++ + +A+ ++I + N+L V L+ WLIFAI G+ ++ K C
Sbjct: 1596 ILKYTRPFRFLYLFEELKYINSAISKSIVDLINILFVQLMVWLIFAIFGIIIYKDKMGYC 1655
Query: 1377 VDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAI 1436
H L+ + +K C E W NFD++G A L LF++ W+ I +
Sbjct: 1656 ---EH-PLNFGV--NKEECIKEGNPWVIHLYNFDNLGNAMLTLFRITACDEWVYICQVCL 1709
Query: 1437 DSREVGRQPIRETNIYM-YLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFM 1495
+SR PI N ++ ++Y + F G++ NF K + +
Sbjct: 1710 NSRSEDLGPILYGNRWITFIYFILFILVGVLFFMGFFAGILFINFQTYKLIL---QKQIL 1766
Query: 1496 TEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTL 1555
T+DQ+ + + K + + P + P P + + +IV ++ +I+L I N +T
Sbjct: 1767 TKDQQLFADVTKMILMEVPNYSNP-PNTFLRRLASDIVKQPSYERLILLTILFNTAILTF 1825
Query: 1556 DHYQQSETFSAVLDYLNMIFIVIFSSECLLKI--FALRYHYFVEPWNLFDFVVVMFSILS 1613
+ + L+Y+ + + LKI F LR Y+ W +F + +++
Sbjct: 1826 FYDSATIQMQQKLEYIYQLLTCFLIFDTYLKILAFGLR-RYWGFSWRRIEFFLSFIALVD 1884
Query: 1614 LV--LSDIIEKYFVSPTL-------LRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPA 1664
L+ LS KY+ T+ +R+ + R L +++ +G+ LL L S
Sbjct: 1885 LIMYLSYDWTKYYYYYTINEYYFIFVRLAFALRNLRTLLIIQQFRGLTRLLRILNYSASF 1944
Query: 1665 LFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGV 1724
LF I L ++ + G FF V+ +++ NF +++I+LF+ T W V
Sbjct: 1945 LFQILCFLISILLFYGYIGCEFFGKVEKGEYINEYMNFSNIGKALIVLFKACTKNNWVRV 2004
Query: 1725 -LDGIINEEECDLPDNERGSPGNCGSATI-GITYLLSYLVISFLIVINMYIAVILENYSQ 1782
+D + C ++E CGS+ I TY ++L++S + N++I +++ + +
Sbjct: 2005 MIDVSDRNKHCQEHESE-----ECGSSWIFASTYFYTFLLLSSFVAFNLFITALVDQFEK 2059
Query: 1783 ATEDVQEGLTD--DDYDMYYEIWQRFDPD-GSQYIRYDQLSDFLDVLEPPL 1830
L ++ D + +W ++ + + + L++FL L PPL
Sbjct: 2060 FFHSQNSVLQTYIENIDPFRTVWCKYSSETKGKQMHSKHLANFLLELGPPL 2110
Score = 58.8 bits (136), Expect = 1e-06
Identities = 53/236 (22%), Positives = 102/236 (43%), Gaps = 23/236 (9%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+ + +K+I + F V+ I+ + + + + QD L +I ++F +E
Sbjct: 454 INISLYKIISHHLFTIFVLGSIIFNIVFFVQSQDETLSQDV-QDDLRSKKKIILILFIVE 512
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
++K + LG KY + D II+++ +++F + F T R R L +
Sbjct: 513 NVLKLIGLGLFKYIWDLQNLFDLIILVLFILHFNYPDIM---VVDFSTARLFRLLTVMSI 569
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSH 1386
S+ +R+++ A+ +I + LL+ +IF FA+ G LF G + H ++
Sbjct: 570 FSKR--LRIMLIAVKHSIKFLLEALLIVIIFSYFFALFGQHLFKGLF-----QYHCYIAE 622
Query: 1387 EIIPDKNAC------------TLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQ 1430
E I K C ++ + N P NFD + +Y + +V F W +
Sbjct: 623 EGIQTKEECGYNLQCKEHELICAKSLSNPNVPTNFDDIFYSYEQVVRVMIFNEWTE 678
Score = 50.4 bits (115), Expect = 5e-04
Identities = 38/170 (22%), Positives = 79/170 (46%), Gaps = 14/170 (8%)
Query: 130 IRRVAIY-ILVHPLFSLFIITTILVNCILMIMPTTPTVE--------STEVIFTGIYTFE 180
I +++Y I+ H LF++F++ +I+ N + + T+ S + I ++ E
Sbjct: 453 IINISLYKIISHHLFTIFVLGSIIFNIVFFVQSQDETLSQDVQDDLRSKKKIILILFIVE 512
Query: 181 SAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVA 240
+ +K++ G F Y+ D N D +++ L + + T R+ R L ++
Sbjct: 513 NVLKLIGLGL----FKYIWDLQNLFDLIILVLFILHFNYPDIMVVDFSTARLFRLLTVMS 568
Query: 241 IVPG-LKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKC 289
I L+ ++ AV S+K L + +++ + FAL G ++ G+ C
Sbjct: 569 IFSKRLRIMLIAVKHSIKFLLEALLIVIIFSYFFALFGQHLFKGLFQYHC 618
Score = 49.2 bits (112), Expect = 0.001
Identities = 42/164 (25%), Positives = 78/164 (47%), Gaps = 16/164 (9%)
Query: 1529 VFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSA-VLDYLNM---IFIVIFSSECL 1584
+++I++ F + ++ I N++ Q ET S V D L I +++F E +
Sbjct: 458 LYKIISHHLFTIFVLGSIIFNIVFFV---QSQDETLSQDVQDDLRSKKKIILILFIVENV 514
Query: 1585 LKIFALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLR 1643
LK+ L + Y + NLFD ++++ IL DI+ F + L R++ V +
Sbjct: 515 LKLIGLGLFKYIWDLQNLFDLIILVLFILHFNYPDIMVVDFSTARLFRLLTVMSIF---- 570
Query: 1644 LVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+K +R +L A+ S+ L L++ + + FA+FG F
Sbjct: 571 ----SKRLRIMLIAVKHSIKFLLEALLIVIIFSYFFALFGQHLF 610
Score = 45.2 bits (102), Expect = 0.018
Identities = 62/277 (22%), Positives = 124/277 (44%), Gaps = 31/277 (11%)
Query: 1532 IVTDKKFDMIIMLFIGL-NMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL 1590
I+ KF + + L N+L ++L Y + + D +FI+I +E LLK+
Sbjct: 1124 IILKNKFVKVFFDSVVLTNILLLSLIGYVDEQRIKKIND----LFILILIAELLLKLLQC 1179
Query: 1591 RYHYFVE-PWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
F N+ D V++ + ++ V ++++ L ++ + V R++K
Sbjct: 1180 GIIRFCSLTTNIIDTVILTCAFITSV--EVMQNLEEENLYLDLLSSFQTFLVYRIIKYNS 1237
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLD-DV---YNFKTF 1705
+ SLP+ N+ LL+ +MFIFA GM+ + K+K LD D+ +F
Sbjct: 1238 FAVKIAKITKKSLPSFCNLILLMVTLMFIFAFIGMNLY---KNKFPLDTDLGLSQSFDDI 1294
Query: 1706 VQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISF 1765
+ + +F + + W G++ + ++ ++P G ++S V++
Sbjct: 1295 QAAFLTVFIRAANDDWIGMMI-MGSQYSYEIPTMFYG--------------VISVYVLN- 1338
Query: 1766 LIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEI 1802
L+ I +A+IL+ +S + ++ DD Y + EI
Sbjct: 1339 LMTIGSILAIILDAFSTFSNHDEDQHKDDQYQVDTEI 1375
Score = 41.9 bits (94), Expect = 0.17
Identities = 22/115 (19%), Positives = 52/115 (45%)
Query: 167 ESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA 226
E E I +S +K+++ GF + + + W +DF+ + +
Sbjct: 1534 EDIESAVNVILLIDSILKIISLGFTQEKGAFTSEFWRLIDFIYQLCYFANCILHYSAFKY 1593
Query: 227 LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
++ + R + + + LK I A+ +S+ +L +++ + + +FA+ G+ IY
Sbjct: 1594 VKILKYTRPFRFLYLFEELKYINSAISKSIVDLINILFVQLMVWLIFAIFGIIIY 1648
>UniRef50_A0BDT8 Cluster: Chromosome undetermined scaffold_101, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_101, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 1487
Score = 162 bits (393), Expect = 1e-37
Identities = 134/619 (21%), Positives = 295/619 (47%), Gaps = 40/619 (6%)
Query: 1213 KLIENTYFETAVITMILLSSLALALE----DVHLPHRPILQDILYYMDRIFTVIFFIEML 1268
+L+E+ F ++ ++ LS++ A++ D H + IL D++ Y + T IF IE++
Sbjct: 735 RLVEHKLFRICLLLVVALSAVKSAVQNPLTDPHSQEKMIL-DVIQY---VTTAIFMIELV 790
Query: 1269 IKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA-M 1327
+ +A G K+ + ++ L+ + ++ ++N ++ G + +LR L L+
Sbjct: 791 LNCVAYGIIKFISQSF--LNILSIINIIVNIISIGLGNPPLFILTLFDSLRVLSFLKTGA 848
Query: 1328 SRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHE 1387
+ ++ V AL A + + L L+ L+++++G+QL +++ C + S
Sbjct: 849 DQYPILKQAVQALFNAFTKMIQLALFSLLILLMYSLIGMQLLNDEFYYC-SLPDGNASRL 907
Query: 1388 IIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIR 1447
+ K C +W N +NFD + ++ LF VAT + WI +M A + + +QP
Sbjct: 908 HLKSKIDCFDIGGSWINQNLNFDTLFESINLLFCVATSEEWIPLMTPAWKAAGIDQQPHH 967
Query: 1448 ETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMK 1507
+TN Y +Y L +F+ ++++ + + ++++ +L + + + Q++++ +
Sbjct: 968 DTNRYWSIYYQMFFFIGNTLVLGMFVTLVVETYIKTREES-QNLHL-LDDKQREWFQIKE 1025
Query: 1508 KMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAV 1567
++ + KP K P I + + ++ + ++ I N++ ++L + + +
Sbjct: 1026 QILNLKPKKKFKPPTIFILNIFYRL--NQFLQIPFLIVILSNIIILSLYYARMGAEYEQA 1083
Query: 1568 LDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSP 1627
LD +N IFI I E L+ + DF ++ I ++LS + F+
Sbjct: 1084 LDQVNQIFIFIQLFEILITTV-----------QVTDFKFKIYEICGILLS--VVSSFLDY 1130
Query: 1628 TLLRVVRVA-KVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSF 1686
+L VV VA +V R+ +L + K I+ L A+ LP ++ ++ +V++ + I
Sbjct: 1131 HILHVVSVAFQVTRIYKLTQHFKTIQHLFHAIFAVLPNTASMLFIMLVVLYCYTIVSCDL 1190
Query: 1687 FMHVKDKGGLDDV-YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEE----C-DLPDNE 1740
F +++ + ++ +F+ F +++ L ++ST W V+ E+ C ++ E
Sbjct: 1191 FAYLRPQTSVNGFDMHFRDFWGALMTLIKVSTGEKWWIVMQETTLEQSPAVACINIESYE 1250
Query: 1741 RGSP---GNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYD 1797
CGS + + +S++++ L+++N+ +A I+ Y Q + Q ++
Sbjct: 1251 EFQEIGFNGCGS-NLSYPFFISFILVFSLMILNLLVANIIGAYEQYHKSEQSAISKYQLL 1309
Query: 1798 MYYEIWQRFDPDGSQYIRY 1816
E+W +FD DG +I Y
Sbjct: 1310 DVIELWSQFDEDGEGFISY 1328
Score = 46.4 bits (105), Expect = 0.008
Identities = 54/257 (21%), Positives = 97/257 (37%), Gaps = 47/257 (18%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAY-VTMGIDLGNLAALR 228
E I + E ++ + G TYLR+ W+ L+F+ + + + + LR
Sbjct: 135 ETICNVFFGIEIIIQCICYGAFFGKGTYLRNIWSCLNFLTFVCTWSIYFDQSITFIQLLR 194
Query: 229 TFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQK 288
R+LR ++ + + + V + +II + + F+++GL + GV ++
Sbjct: 195 VIRLLRLVRLLQEIQYFREQVENFFSCFLTIHTIIIPVVIVIFGFSVIGLHLLRGVTGRR 254
Query: 289 CVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGP 348
C K + D N C G +C GY C+ F
Sbjct: 255 CAK--------NGIIDLNIRSLC--------------------GEWECPDGYECIDQFHS 286
Query: 349 NP------NYGYTSFDTFGWAFLSAFRLMTQDYWE--NLY----------QLFFVVIIFL 390
YGY FDT +FLS F W Y ++F+ ++F+
Sbjct: 287 EDLNYLDFYYGYYHFDTIYDSFLSGFMFFNATGWSPTTFYFWKAVTPPATAIYFIFMLFI 346
Query: 391 GSFYLVNLILAIVAMSY 407
+ L +L+LA + S+
Sbjct: 347 LHYTLSDLLLATLYESF 363
Score = 37.9 bits (84), Expect = 2.8
Identities = 30/147 (20%), Positives = 72/147 (48%), Gaps = 11/147 (7%)
Query: 1227 MILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCW 1286
+I+ S++ L ++ V H YY D I + + L+K + F+K +
Sbjct: 449 LIIASTIVLCVDQVEKRHPKE-----YYADMIMNFLIILLTLLKLIF--FKKSRRKLYII 501
Query: 1287 LDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG---MRVVVNALVQA 1343
+D I+ + +I + F ++ +A R ++ + +++ +R+++ L++
Sbjct: 502 VDVILSLGLIIVIILEFLNFQS-NVFIIIKAFKAFRVIKLIYKLEYFGVIRLLLRCLIET 560
Query: 1344 IPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
I I +++++ +IF + +I+G +LFA
Sbjct: 561 IIKIRHLIILWVIFAFLISIIGQELFA 587
>UniRef50_P50077 Cluster: Calcium-channel protein CCH1; n=4; cellular
organisms|Rep: Calcium-channel protein CCH1 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 2039
Score = 155 bits (375), Expect = 2e-35
Identities = 140/628 (22%), Positives = 265/628 (42%), Gaps = 33/628 (5%)
Query: 1220 FETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGF--- 1276
F A I +I+ S L +H H+ + +D F F IE ++K +A GF
Sbjct: 1212 FALATILLIVCSCYVTPLYRMH--HKMGTWNWSSALDCAFIGAFSIEFIVKTVADGFIYS 1269
Query: 1277 -QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRV 1335
Y N W ++DF +++ IN +A L G + + + L ALR LR ++ R
Sbjct: 1270 PNAYLRNPWNFIDFCVLISMWINLIAYLKNNGNLS--RIFKGLTALRALRCLTISNTARQ 1327
Query: 1336 VVNALV-QAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD--MNHTTLSHEIIPDK 1392
N ++ + IF L+ L F + G+ +F G+ C D + +E
Sbjct: 1328 TFNLVMFDGLNKIFEAGLISLSLLFPFTVWGLSIFKGRLGTCNDGSLGRADCYNEYSNSV 1387
Query: 1393 NACTLENYTWENSP-MNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNI 1451
+ + P ++ D A+ L+Q+ + +GW+ ++ + ++S +G +
Sbjct: 1388 FQWDIMSPRVYQQPYLHLDSFASAFSSLYQIISLEGWVDLLENMMNSSGIGTPATVMGSA 1447
Query: 1452 YMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGS 1511
L+ LNLF+ I++N Q + G + + T ++K + + K +
Sbjct: 1448 GNALFLVLFNFLSMVFILNLFVSFIVNN---QARTTGSA---YFTIEEKAWLESQKLLSQ 1501
Query: 1512 KKPLKAIPR--PRWRPQAIVFEIVTDKK---FDMIIMLFIGLNMLTMTLDHYQQSETFSA 1566
KP KAIP R + +++ +KK + + + + L+++ + Y
Sbjct: 1502 AKP-KAIPNLIELSRVRQFFYQLAVEKKNFYYASFLQVVLYLHIIMLLSRSYNPGNLIGY 1560
Query: 1567 VLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVS 1626
Y V E L YF + WN ++ I++ +++ + S
Sbjct: 1561 QGVYFMFSTSVFLIQEALHMCGEGPRLYFRQKWNSIRLSII---IIAFIMNAVAFHVPAS 1617
Query: 1627 PTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAM-SLPALFNICLLLFLVMFIFAIFGMS 1685
++ + + + T L AM SLP + ++ ++ ++AI
Sbjct: 1618 HYWFHNIKGFFLLVIFLFIIPQNDTLTELLETAMASLPPILSLTYTWGVLFLVYAIALNQ 1677
Query: 1686 FFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVL-DGIINEEECDLPDNERGSP 1744
F + D NF+T ++SMI+LF+ S GW+ ++ D ++E C DN +
Sbjct: 1678 IFGLTRLGSNTTDNINFRTVIKSMIVLFRCSFGEGWNYIMADLTVSEPYCSSDDNSTYT- 1736
Query: 1745 GNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQA--TEDVQEGLTDDDYDMYYEI 1802
+CGS T L+S+ +IS I +NM++++I+ N+S + + G+ + Y E
Sbjct: 1737 -DCGSETYAYLLLMSWNIISMYIFVNMFVSLIIGNFSYVYRSGGSRSGINRSEIKKYIEA 1795
Query: 1803 WQRFDPDGSQYIRYDQLSDFLDVLEPPL 1830
W +FD DG+ + L + + PL
Sbjct: 1796 WSKFDTDGTGELELSYLPRIMHSFDGPL 1823
Score = 61.7 bits (143), Expect = 2e-07
Identities = 112/518 (21%), Positives = 211/518 (40%), Gaps = 69/518 (13%)
Query: 1308 GIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQ 1367
GI+ FK + LR LR + + GM ++ L IP + NV + + FW+ F I+GVQ
Sbjct: 521 GIRIFKPLAILRILRLVNVDT---GMPSILRGLKYGIPQLVNVSSMLVYFWIFFGILGVQ 577
Query: 1368 LFAGKYFK-CVDMNHTTLSHEIIPDKNAC---------TLENYTWENSPMNFDHVGKAYL 1417
+F G + + CV N + D C +NY +E+ + V K +L
Sbjct: 578 IFQGSFRRQCVWFNPEDPTDTYQYDMQFCGGYLDPVTKRKQNYIYEDG--SEGSVSKGFL 635
Query: 1418 ------CLFQVATFKGWIQIMNDAIDSRE---VGRQPIRETNIYMY----------LYXX 1458
C+ + G I N ++S E V T++ Y L+
Sbjct: 636 CPQYSKCVSNANPYNGRISFDN-IVNSMELVFVIMSANTFTDLMYYTMDSDEMAACLFFI 694
Query: 1459 XXXXXXXXXTLNLFIGVIIDNF---NEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKK-- 1513
LNL I V++ +F NE+ KK + F+ +K Y A G K
Sbjct: 695 VCIFVLTIWLLNLLIAVLVSSFEIANEEYKK-----KKFIYGSRKTGYVARIVTGYWKYF 749
Query: 1514 PLKA--IPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYL 1571
LKA P W + + I + +F +I++ + M ++ + + +L
Sbjct: 750 KLKANQTKFPNWSQKGLA--IYSHVEFIFVILIICDIGM-RASVKVSTSANCNNILLKTD 806
Query: 1572 NMIFIVIFSSECLLKIFAL--RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTL 1629
I IV+F + L + + +P ++DF++ SI++LV+S + + V +
Sbjct: 807 RGISIVLFIESLARLVLYLPNMWKFLTKPSYVYDFII---SIITLVISCLAVE-GVLGHM 862
Query: 1630 LRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMH 1689
+ + + R R++ + L + + ++N+ F F+ AI +F
Sbjct: 863 YAWLSIFHISRFYRVIISFNLTKKLWKQILSNGVMIWNLSSFYFFFTFLVAIIMAVYFEG 922
Query: 1690 V-KDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCG 1748
V + D + + S + LF + ++ W +L + ++ SP N
Sbjct: 923 VIPPEEMADQPFGMYSLPNSFLSLFIIGSTENWTDILYAL-----------QKHSP-NIS 970
Query: 1749 SATIGITYLLSYLVISFLIVINMYIAVILENYSQATED 1786
S + + + ++S +++N++IA+I E+ E+
Sbjct: 971 STFFCSVFFIIWFLLSNSVILNIFIALISESMEVKEEE 1008
Score = 57.6 bits (133), Expect = 3e-06
Identities = 57/236 (24%), Positives = 105/236 (44%), Gaps = 27/236 (11%)
Query: 194 PFTYLRDAWNWLDFVVIALAYVTMGIDLGNL---AALRTFR---VLRALKTVAIVPGLKT 247
P + R +WN +D V ++ M + + + +R F+ +LR L+ V + G+ +
Sbjct: 486 PRAFARSSWNRIDLVSSVSFWLGMFLSIKSYDTKTGIRIFKPLAILRILRLVNVDTGMPS 545
Query: 248 IVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENW 307
I+ + + L +V + ++ F ++G+QI+ G ++CV PED + D +
Sbjct: 546 ILRGLKYGIPQLVNVSSMLVYFWIFFGILGVQIFQGSFRRQCVWFNPEDPTDTYQYDMQF 605
Query: 308 -----ERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGW 362
+ + + N+ E G G+ S C C+ NP G SFD
Sbjct: 606 CGGYLDPVTKRKQNYIYEDGSE---GSVSKGFLCPQYSKCVS--NANPYNGRISFDNIVN 660
Query: 363 AFLSAFRLM-----------TQDYWENLYQLFFVVIIFLGSFYLVNLILAIVAMSY 407
+ F +M T D E LFF+V IF+ + +L+NL++A++ S+
Sbjct: 661 SMELVFVIMSANTFTDLMYYTMDSDEMAACLFFIVCIFVLTIWLLNLLIAVLVSSF 716
Score = 56.4 bits (130), Expect = 7e-06
Identities = 35/118 (29%), Positives = 62/118 (52%), Gaps = 5/118 (4%)
Query: 173 FTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDL---GNLAAL-R 228
F G ++ E VK +A GFI P YLR+ WN++DF V+ ++ + L GNL+ + +
Sbjct: 1249 FIGAFSIEFIVKTVADGFIYSPNAYLRNPWNFIDFCVLISMWINLIAYLKNNGNLSRIFK 1308
Query: 229 TFRVLRALKTVAIVPGLKTIVGAVI-ESVKNLRDVIILTMFSLSVFALMGLQIYMGVL 285
LRAL+ + I + V+ + + + + ++++ L F + GL I+ G L
Sbjct: 1309 GLTALRALRCLTISNTARQTFNLVMFDGLNKIFEAGLISLSLLFPFTVWGLSIFKGRL 1366
Score = 41.1 bits (92), Expect = 0.30
Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 3/89 (3%)
Query: 1599 WNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFAL 1658
WN D V + L + LS K + + T +R+ + + R+LRLV G+ ++L L
Sbjct: 494 WNRIDLVSSVSFWLGMFLSI---KSYDTKTGIRIFKPLAILRILRLVNVDTGMPSILRGL 550
Query: 1659 AMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+P L N+ +L F I G+ F
Sbjct: 551 KYGIPQLVNVSSMLVYFWIFFGILGVQIF 579
>UniRef50_Q7SCM1 Cluster: Putative uncharacterized protein NCU02762.1;
n=4; Pezizomycotina|Rep: Putative uncharacterized protein
NCU02762.1 - Neurospora crassa
Length = 2218
Score = 153 bits (371), Expect = 5e-35
Identities = 145/659 (22%), Positives = 276/659 (41%), Gaps = 35/659 (5%)
Query: 1217 NTYFETAVITMILLSSLALAL--EDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLAL 1274
+T A++ M++L+ + L ++ + D ++D F ++F +E LIK +A
Sbjct: 1206 STLIYAAIVIMVVLACITTPLYQKEYFEKYGENAFDWFRWVDTGFAIVFTLEALIKVIAD 1265
Query: 1275 GF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGI-QAFKTMRTLRALRPLRAMSR 1329
GF YF + W +D I+++ IN + G + +A + LRALR L
Sbjct: 1266 GFLWTPNAYFRSTWGVIDAIVLITLWINVITLFTRNGAVSRAVGAFKALRALRLLNISE- 1324
Query: 1330 MQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEII 1389
M + L+ I + V + + FAI GV LF GK C D + +S +
Sbjct: 1325 -SAMDTFHSLLIVGGWKILSAAFVSISLLIPFAIYGVNLFHGKLLACNDSSEGIVSLDDC 1383
Query: 1390 PDKNACTLENYTWE--------NSPMNFDHVGKAYLCLFQVATFKGWIQIMN--DAIDSR 1439
+ T N W N +FD G + LFQ+ + +GW+ + AI R
Sbjct: 1384 FGEWNSTPYNNNWPVLAPRSVANPYFSFDDFGSSLFILFQIVSQEGWVDVSFALQAITGR 1443
Query: 1440 EVGRQP-IRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTED 1498
+ Q + L+ L LFI V + N+ EQ A F+T +
Sbjct: 1444 GLQPQSGAPYSGQGNALFLVVFNLLATVFVLTLFISVFMRNYTEQTGVA------FLTAE 1497
Query: 1499 QKKYYNAMKKMGSKKPLKAI---PRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTL 1555
Q+ + K + P K+ + +W+ I K+ M I + L+++ +
Sbjct: 1498 QRSWLELRKLLRQISPSKSSYDESKNKWKIWCHKRAIEKRGKWYMAITSVLVLHLILLLS 1557
Query: 1556 DHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEP-WNLFDFVVVMFSILSL 1614
+ Y + + ++ D L ++F +I+ + +++I L + F + W++F + V + +
Sbjct: 1558 EFYSEPDWWTNTRDALFLLFTLIYIANIVIRIVGLGWSRFRKSSWDMFSLITVTGAFATT 1617
Query: 1615 VLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFL 1674
+L K T +++ + V VL L+ + L A SL + ++ +
Sbjct: 1618 ILFMTNTKL---DTYIQLHKFFLVAIVLMLIPRNDALDQLFKTAAASLTTIGSLLATWLV 1674
Query: 1675 VMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEEC 1734
+FAI F + D N +T ++ILLF+ S GW+ V++ +
Sbjct: 1675 FFLVFAIALTQTFSLTRFGNSTDYYVNLRTVPNALILLFRFSCGEGWNQVMEDFAKIKPP 1734
Query: 1735 DLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQE-GLTD 1793
++ S +CGS +++ +IS I +N+++++I E++S + + D
Sbjct: 1735 LCVESTNFSDSDCGSTAWARALFIAWNIISMYIFVNLFVSLIYESFSYVYQRTSGLAMVD 1794
Query: 1794 -DDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHKPNKYKIISMDIPICRGD 1851
D+ + E W+ DP G+ +I + L L ++ + + + RG+
Sbjct: 1795 RDELRRFKEAWRSVDPSGTGFISKEAFPRLLGELSGVFEMRIYESHDSVRQILEDVRGE 1853
Score = 59.3 bits (137), Expect = 1e-06
Identities = 39/131 (29%), Positives = 62/131 (47%), Gaps = 6/131 (4%)
Query: 1287 LDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPS 1346
LDF+ V+ I+FV + G R L LR +R ++ +G +++ +L +A P
Sbjct: 497 LDFVAVVSFWISFVLGVTGLESKHHMYVFRMLSCLRIIRLLALTKGNLIILRSLKKAAPL 556
Query: 1347 IFNVLLVCLIFWLIFAIMGVQLFAGKYFK-C--VDMNH-TTLSHEIIPDKNAC--TLENY 1400
+ V + FWL+FAI+GVQ F + C +D + T PD C ++N
Sbjct: 557 LVRVSFLMGFFWLLFAIIGVQSFKSSLSRQCLWIDPDDPTNFQAAYTPDMTFCGGHIDNV 616
Query: 1401 TWENSPMNFDH 1411
T E P + H
Sbjct: 617 TGETMPWVYSH 627
Score = 59.3 bits (137), Expect = 1e-06
Identities = 42/152 (27%), Positives = 75/152 (49%), Gaps = 16/152 (10%)
Query: 1640 RVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF---MHVKDKGGL 1696
RV RLV R L+ + ++ + N+ +FL+ F+ AIF F + +D GG
Sbjct: 866 RVYRLVMVIPMTRKLIRLVLGNVTGIGNLMSFVFLITFLMAIFAAQLFRGELPREDDGGE 925
Query: 1697 DDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITY 1756
+ F T S + ++Q+ ++ W +L + S + +A IG +
Sbjct: 926 EIRIPFNTIYNSFLGMYQVMSTENWTDILYSVT------------ASTHHLHTAWIGAIF 973
Query: 1757 LLSYLVISFLIVINMYIAVILENYSQATEDVQ 1788
L+ + ++++ I+INM+IAVI EN+ EDV+
Sbjct: 974 LVGWFILAYFILINMFIAVIQENF-DVGEDVK 1004
Score = 52.0 bits (119), Expect = 2e-04
Identities = 52/240 (21%), Positives = 103/240 (42%), Gaps = 30/240 (12%)
Query: 197 YLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVG--AVIE 254
+LR +N LDFV + +++ + + L + V R L + I+ L G ++
Sbjct: 489 FLRHGFNRLDFVAVVSFWISFVLGVTGLESKHHMYVFRMLSCLRIIRLLALTKGNLIILR 548
Query: 255 SVKNLRDVIILTMFSLS----VFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERF 310
S+K +++ F + +FA++G+Q + L+++C+ + P+D + F
Sbjct: 549 SLKKAAPLLVRVSFLMGFFWLLFAIIGVQSFKSSLSRQCLWIDPDDPTNFQAAYTPDMTF 608
Query: 311 C----QNETN----WYGEGGDYPLCGNSSGAGQCEPGYVCLQGF----GPNPNYGYTSFD 358
C N T W L +G + + G++C +G NP G +FD
Sbjct: 609 CGGHIDNVTGETMPWVYSHEKESLIDLKNGTSRAK-GFICPRGSICIRQENPFNGTVNFD 667
Query: 359 TFGWAFLSAFRLMTQDYWENLY-----------QLFFVVIIFLGSFYLVNLILAIVAMSY 407
G + F +M+ + W +L LF+ I + ++ NL++A++ S+
Sbjct: 668 DIGHSLELVFVIMSANTWSDLMYHTIRSDFLPSALFYGAGILIMLLWMTNLLIAVITSSF 727
Score = 47.6 bits (108), Expect = 0.003
Identities = 52/209 (24%), Positives = 93/209 (44%), Gaps = 33/209 (15%)
Query: 173 FTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAY---VTMGIDLGNLA-ALR 228
F ++T E+ +KV+A GF+ P Y R W +D +V+ + +T+ G ++ A+
Sbjct: 1250 FAIVFTLEALIKVIADGFLWTPNAYFRSTWGVIDAIVLITLWINVITLFTRNGAVSRAVG 1309
Query: 229 TFRVLRALKTVAI-VPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQ 287
F+ LRAL+ + I + T +I + +++ L FA+ G+ ++ G L
Sbjct: 1310 AFKALRALRLLNISESAMDTFHSLLIVGGWKILSAAFVSISLLIPFAIYGVNLFHGKLL- 1368
Query: 288 KCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFG 347
C D S G ++ ++ C E N ++P+ S A
Sbjct: 1369 AC-----NDSSEGIVSLDD----CFGEWNSTPYNNNWPVLAPRSVA-------------- 1405
Query: 348 PNPNYGYTSFDTFGWAFLSAFRLMTQDYW 376
NP Y SFD FG + F++++Q+ W
Sbjct: 1406 -NP---YFSFDDFGSSLFILFQIVSQEGW 1430
>UniRef50_Q22YT0 Cluster: Cation channel family protein; n=1;
Tetrahymena thermophila SB210|Rep: Cation channel family
protein - Tetrahymena thermophila SB210
Length = 2155
Score = 152 bits (368), Expect = 1e-34
Identities = 130/596 (21%), Positives = 253/596 (42%), Gaps = 25/596 (4%)
Query: 1249 QDILYYMDRIFTVIFFIEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALC 1304
Q ++ I T F IE +++ +A GF + W + I+ F
Sbjct: 1182 QVVIIVFHAILTAFFIIENIMQIIAYGFIFSPTSFIQRNWFFNSIDIITTVASFFYTVDF 1241
Query: 1305 GAGGIQAFKTMRTLRALRPLRAMS-RMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAI 1363
+ FK + LR +S +++ + L++ +P + +++ IF LI
Sbjct: 1242 WPRSVYVFKFILILRLTVLFSFLSHQVKEVHHAGMILIKCLPRMLRLIIFAAIFLLISGA 1301
Query: 1364 MGVQLFAGKYFKCVDMNHTTLSHEIIPD---KNACTLENYTWENSPMNFDHVGKAYLCLF 1420
+ +L G C + + + IP+ K C W +S NF+++ + LF
Sbjct: 1302 LTTKLLKGSMHHCYIGDESDGENSEIPEIITKFDCLDLGGDWIDSQYNFNNIINSLQILF 1361
Query: 1421 QVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNF 1480
V + +GWI IM + DS N ++ LN+F+G++++
Sbjct: 1362 MVQSSEGWIHIMFNVYDSTSPELNSHYRQNSLWAIFFIQFFFIANICILNMFVGLVVETQ 1421
Query: 1481 NEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFE-IVTDKKFD 1539
E + + ++ + QK++ K + KP + P+ + + +F+ ++
Sbjct: 1422 LEMIESEHKTKDLH--KFQKEWLFIKKSIYQLKPSAKVKIPQDKVRKFLFDNLIQGNALK 1479
Query: 1540 MIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPW 1599
+I F N + + L +Q++ L +N + +V E ++ L YF EPW
Sbjct: 1480 IIFYTFTLANCINLMLFRNRQTQEEIDKLYLVNEVCLVAMIIEIFCRMVCLNLKYFTEPW 1539
Query: 1600 NLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAK---VGRVLRLVKGAKGIRTLLF 1656
N+ D +V+ ++L E L VAK + R R++K I+ L
Sbjct: 1540 NVIDLSIVIIGWINLRFQQTNEFEIFDRGLRIFDGVAKGLQLLRFYRIMKHFTIIKKLFK 1599
Query: 1657 ALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDV-YNFKTFVQSMILLFQM 1715
+L ++ ++F I +L + +FI + M+ F ++K++ ++ F+ F ++ L ++
Sbjct: 1600 SLQYAISSIFGIFQVLIIFLFISVLISMNLFPYIKEQKIINGYDVTFRDFPNALFTLIRV 1659
Query: 1716 STSAGWDGVL---------DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFL 1766
TS W V D + E D ++ CGS I + YLV + L
Sbjct: 1660 MTSEYWYVVAQEGAKKMQPDFVCFENIILYEDYQKYGQNACGSRLSYIFFYGFYLVFT-L 1718
Query: 1767 IVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDF 1822
+++N++IA I+E+Y +A + + D E+W+++DP+G YI Y + F
Sbjct: 1719 VILNIFIATIIESYKEAFSADESAVNHYQLDDVLELWKQYDPEGKGYISYKEFWQF 1774
>UniRef50_Q1HHN2 Cluster: High-affinity cell membrane calcium channel;
n=2; Filobasidiella neoformans|Rep: High-affinity cell
membrane calcium channel - Cryptococcus neoformans var.
grubii (Filobasidiella neoformans var.grubii)
Length = 2091
Score = 149 bits (362), Expect = 6e-34
Identities = 148/644 (22%), Positives = 289/644 (44%), Gaps = 54/644 (8%)
Query: 1211 TFKLIENTYFETAVITMILLSSLALAL--EDVHLPHRPILQDILYYMDRIFTVIFFIEML 1268
T LI T AV+ I+++++A + + H + + +IF +E
Sbjct: 1160 TLALIVKTVVFLAVVASIVVAAIASPSYRREYYADHGISRRTWFDLTEVALGLIFVLEAA 1219
Query: 1269 IKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPL 1324
+K +A GF Y + W LDFII++ LIN +L GG+ + R L++ R L
Sbjct: 1220 MKIVADGFIFAPNAYLLSLWNVLDFIILITLLINITTSLIFIGGLS--RVTRALKSFRAL 1277
Query: 1325 RAMSRMQGMRVVVNALVQA-IPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTT 1383
R ++ +R ++A++ A I + + +++ + FA+ G+ +F+G + C D + +
Sbjct: 1278 RLITLFGRLRDTLHAVLFAGALKILDASIFMILYLIPFAVWGLNIFSGLLYYCNDDDSSG 1337
Query: 1384 LSHEIIP------DKNACTLENYTWEN-----SPMNFDHVGKAYLCLFQVATFKGWIQIM 1432
L+ I D + L W N S +FD ++ L LF++ + +GWI +M
Sbjct: 1338 LTSCIGEFSTSSIDDSLTYLVPRVWVNPTVDESIWSFDSFRESILILFEIVSLEGWIDVM 1397
Query: 1433 NDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLE 1492
++ +QP + + + +Y NLF GVII F K + S
Sbjct: 1398 ASVMNIVGRDQQPQNQASQWNAIY---------LVIFNLFGGVIILTFIIIKNFSTRSGN 1448
Query: 1493 MFMTEDQKKYYNAMKKMGSKKPLKAIP--RPRWRPQAIVFEIVTDKK--FDMIIMLFIGL 1548
+T +Q+++ + K + ++ P +P RPR +A ++ +K + + + L
Sbjct: 1449 ALLTSEQRQWVDLSKFIKAQTP-SQLPKGRPRLPFRAWCYDRAVNKNGFWAVGFTMIYYL 1507
Query: 1549 NMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYF-VEPWNLFDFVVV 1607
++L + ++ + ++ LD++ + V+++ + L++ + L + F WN+FD +V+
Sbjct: 1508 HILLLMMEDFSENLLNEVQLDWIFLFLTVLYAVDLLVRFYGLGFKSFKSNGWNIFDLIVI 1567
Query: 1608 MFSILSLV--LSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPAL 1665
S + + L + +++ ++ V L+LV+ + L SLPA+
Sbjct: 1568 TGSFATTIPALQADSSGGTANQANVQLQKLFLVSISLKLVQRISSLNQLFKTSVASLPAI 1627
Query: 1666 FNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVY-NFKTFVQSMILLFQMSTSAGWDGV 1724
N+ LL + +AI + F K+ + N+ TF ++++L MST GW+G
Sbjct: 1628 GNLFLLWATIFIFYAILYLEVFGLTKEGNNAGTRFQNYYTFGNALLMLAFMSTGEGWNGY 1687
Query: 1725 L-DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQA 1783
+ D I E C +N +CGSA I +NM+ V++E+++
Sbjct: 1688 MHDYTIQEPRC--TENGNFLESDCGSAP------------GAYIFVNMFTGVVVESFAYV 1733
Query: 1784 TE-DVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVL 1826
+ + L ++ + ++W FD YI+ L F L
Sbjct: 1734 YQMPGKSSLNREEMRAFKQLWAEFDSQRIGYIKRKDLIRFFSRL 1777
Score = 69.7 bits (163), Expect = 7e-10
Identities = 110/527 (20%), Positives = 211/527 (40%), Gaps = 43/527 (8%)
Query: 1279 YFTNAWCWLDFIIVMVSLINFVAALCG--AGGIQAFKTMRTLRALRPLRAMSRMQGMRVV 1336
Y ++W +D I V I F AL G A + R L LR R + G +
Sbjct: 464 YLRHSWHRIDMIAVFAFWITFFLALTGYEATADRHVYIFRALSVLRAGRLLVITSGTTTI 523
Query: 1337 VNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACT 1396
+++L +A P + V + IF+I+GVQ F G + + + S +I + C
Sbjct: 524 LHSLKRAGPMLITVSYFLVFAACIFSIIGVQSFRGSFRRACVLTDPHNSSNVIQLETQCG 583
Query: 1397 --LENYTWEN-SPMNFDHVG-----KAYLC-LFQVA--TFKGWIQIMN--DAIDSREVGR 1443
L+ ++++ S ++ D K Y+C L Q+ T + +N D + S V
Sbjct: 584 GWLDPTSFKSMSYLSLDGTSSAVPPKGYICPLGQICMTTDENPNNNVNSFDNVFSSLVQV 643
Query: 1444 QPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNF---NEQKKKAGGSLEMFMTEDQK 1500
+ N + + +L GVI+ NF N + E ++
Sbjct: 644 IIVISINTWAPVMYMAMDSDFFGSSLFFIAGVIVLNFWLINLLIAVVVNTFSDIRAETKR 703
Query: 1501 KYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQ 1560
+ A + +P A + + + + +K ++ ++ + +++
Sbjct: 704 SAFGAGETFLGTEPHWAAEDEKTKNNRL---LAFYQKTEIFWVILVVADLVAQGSKSSSS 760
Query: 1561 SETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVV-MFSILSLVLSDI 1619
E+ +LD L + F + F E +++ A YF + W F + F + + I
Sbjct: 761 PESMLRLLDRLELAFTLAFDLEIIIRFLA----YFPD-WRTFFYRKRNCFDLFLAIACSI 815
Query: 1620 IEKYFVSPT-LLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFI 1678
I+ +S + + + V ++ R R++ ++ LL + S L N+ + LFL+ F+
Sbjct: 816 IQIPAISNSPIYPWLTVFQLIRWYRVILAFPRMKPLLITVFGSFSGLLNMVIFLFLMNFL 875
Query: 1679 FAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPD 1738
A+ + F + G + F S + ++Q+ +S W D+
Sbjct: 876 GALMALQLFRGDLEAG---ETITFSQTYNSFLGMYQIFSSENWT------------DIVY 920
Query: 1739 NERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATE 1785
+ G+ I +L + + S IV+ M+IAVI EN++ A E
Sbjct: 921 DTMGAESQYKQNIIAAIFLCGWFLFSNFIVLQMFIAVINENFAIAEE 967
Score = 64.1 bits (149), Expect = 4e-08
Identities = 40/122 (32%), Positives = 64/122 (52%), Gaps = 5/122 (4%)
Query: 169 TEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV---TMGIDLGNLA 225
TEV I+ E+A+K++A GFI P YL WN LDF+++ + T I +G L+
Sbjct: 1206 TEVALGLIFVLEAAMKIVADGFIFAPNAYLLSLWNVLDFIILITLLINITTSLIFIGGLS 1265
Query: 226 AL-RTFRVLRALKTVAIVPGLKTIVGAVI-ESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
+ R + RAL+ + + L+ + AV+ + D I + L FA+ GL I+ G
Sbjct: 1266 RVTRALKSFRALRLITLFGRLRDTLHAVLFAGALKILDASIFMILYLIPFAVWGLNIFSG 1325
Query: 284 VL 285
+L
Sbjct: 1326 LL 1327
Score = 58.4 bits (135), Expect = 2e-06
Identities = 58/249 (23%), Positives = 106/249 (42%), Gaps = 28/249 (11%)
Query: 184 KVMAR--GFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA--------LRTFRVL 233
K MAR G Q YLR +W+ +D + + ++T + L A R VL
Sbjct: 449 KAMARQKGLSDQGRPYLRHSWHRIDMIAVFAFWITFFLALTGYEATADRHVYIFRALSVL 508
Query: 234 RALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVF 293
RA + + I G TI+ ++ + L V +F+ +F+++G+Q + G + CV
Sbjct: 509 RAGRLLVITSGTTTILHSLKRAGPMLITVSYFLVFAACIFSIIGVQSFRGSFRRACVLTD 568
Query: 294 PEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQ----CEPGYVCLQGFGPN 349
P + S N+ + + + L G SS C G +C+ N
Sbjct: 569 PHNSS--NVIQLETQCGGWLDPTSFKSMSYLSLDGTSSAVPPKGYICPLGQICMT-TDEN 625
Query: 350 PNYGYTSFDTFGWAFLSAFRLMTQDYWENLY-----------QLFFVVIIFLGSFYLVNL 398
PN SFD + + +++ + W + LFF+ + + +F+L+NL
Sbjct: 626 PNNNVNSFDNVFSSLVQVIIVISINTWAPVMYMAMDSDFFGSSLFFIAGVIVLNFWLINL 685
Query: 399 ILAIVAMSY 407
++A+V ++
Sbjct: 686 LIAVVVNTF 694
>UniRef50_Q4SZH3 Cluster: Chromosome 18 SCAF11624, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 18 SCAF11624, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1395
Score = 148 bits (359), Expect = 1e-33
Identities = 72/208 (34%), Positives = 122/208 (58%), Gaps = 8/208 (3%)
Query: 1272 LALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAF---KTMRTLRALRPLRAMS 1328
L G + Y ++W LD ++V VSL++ + ++ AGG + F + +R LR LRPLR +S
Sbjct: 1071 LYFGHRVYLQSSWNILDGLLVFVSLVDILVSVASAGGNRIFGILRVLRLLRTLRPLRVIS 1130
Query: 1329 RMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEI 1388
R G+++VV L+ ++ I N++L+C F+++F I+GVQLF GK++ C ++ +
Sbjct: 1131 RAPGLKLVVETLITSLRPIGNIVLICCAFFIVFGILGVQLFKGKFYYCDGLDVSN----- 1185
Query: 1389 IPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRE 1448
I +K C Y W+ NFD++G+A + LF ++ GW+ IM D +D+ V +QP R
Sbjct: 1186 ITNKTQCLEAGYRWKRRKYNFDNLGQALMSLFVLSCKDGWVSIMYDGLDAVGVDQQPKRN 1245
Query: 1449 TNIYMYLYXXXXXXXXXXXTLNLFIGVI 1476
+ +M L+ LN+F+GV+
Sbjct: 1246 HDPWMLLFFISFLLIVSFFVLNMFVGVV 1273
Score = 91.5 bits (217), Expect = 2e-16
Identities = 61/156 (39%), Positives = 88/156 (56%), Gaps = 11/156 (7%)
Query: 1219 YFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGF-- 1276
+FE I ILL+ + L + H P L L D IF V F EML+K +ALG
Sbjct: 1 WFERVSILAILLNCVTLGMFQP-CDHTPFLLQALD--DGIF-VFFAGEMLVKMVALGVIG 56
Query: 1277 -QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRV 1335
Y + W LDF IV+V ++ + +L G + +RT+R LRPLRA++R+ MR+
Sbjct: 57 QNGYLGDTWNRLDFFIVIVGMLEY--SLDGHN--VSLSAIRTVRVLRPLRAINRVPSMRI 112
Query: 1336 VVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
+V L+ +P + NVL +C + IF I+GVQL+AG
Sbjct: 113 LVTLLLDTLPMLGNVLALCFFVFFIFGIVGVQLWAG 148
Score = 85.8 bits (203), Expect = 1e-14
Identities = 51/154 (33%), Positives = 85/154 (55%), Gaps = 8/154 (5%)
Query: 143 FSLFIITTILVNCIL--MIMPTTPTVESTEVIFTGIYTF---ESAVKVMARGFILQPFTY 197
F I IL+NC+ M P T + + GI+ F E VK++A G I Q Y
Sbjct: 2 FERVSILAILLNCVTLGMFQPCDHTPFLLQALDDGIFVFFAGEMLVKMVALGVIGQN-GY 60
Query: 198 LRDAWNWLDFVVIALAYVTMGIDLGN--LAALRTFRVLRALKTVAIVPGLKTIVGAVIES 255
L D WN LDF ++ + + +D N L+A+RT RVLR L+ + VP ++ +V ++++
Sbjct: 61 LGDTWNRLDFFIVIVGMLEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDT 120
Query: 256 VKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKC 289
+ L +V+ L F +F ++G+Q++ G+L +C
Sbjct: 121 LPMLGNVLALCFFVFFIFGIVGVQLWAGLLRNRC 154
Score = 63.7 bits (148), Expect = 5e-08
Identities = 43/173 (24%), Positives = 85/173 (49%), Gaps = 23/173 (13%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTF 179
+L++ P N R ++ H +F I+ I +NCI + + ++ V+ G+Y F
Sbjct: 1015 SLYLFAPHNKFRLWCQRVIGHKMFDHVILLFIFLNCITIALERPDIQPNSMVVAMGLY-F 1073
Query: 180 ESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDL---------GNLAALRTF 230
V YL+ +WN LD +++ ++ V + + + G L LR
Sbjct: 1074 GHRV-------------YLQSSWNILDGLLVFVSLVDILVSVASAGGNRIFGILRVLRLL 1120
Query: 231 RVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
R LR L+ ++ PGLK +V +I S++ + +++++ VF ++G+Q++ G
Sbjct: 1121 RTLRPLRVISRAPGLKLVVETLITSLRPIGNIVLICCAFFIVFGILGVQLFKG 1173
Score = 61.3 bits (142), Expect = 3e-07
Identities = 48/154 (31%), Positives = 77/154 (50%), Gaps = 13/154 (8%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL----RYH 1593
F+ + +L I LN +T+ + +Q + +L L+ V F+ E L+K+ AL +
Sbjct: 2 FERVSILAILLNCVTLGM--FQPCDHTPFLLQALDDGIFVFFAGEMLVKMVALGVIGQNG 59
Query: 1594 YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRT 1653
Y + WN DF +V+ +L L + + VS + +R VRV R LR + +R
Sbjct: 60 YLGDTWNRLDFFIVIVGMLEYSL----DGHNVSLSAIRTVRVL---RPLRAINRVPSMRI 112
Query: 1654 LLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
L+ L +LP L N+ L F V FIF I G+ +
Sbjct: 113 LVTLLLDTLPMLGNVLALCFFVFFIFGIVGVQLW 146
Score = 61.3 bits (142), Expect = 3e-07
Identities = 31/91 (34%), Positives = 52/91 (57%), Gaps = 2/91 (2%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W LR+K ++ + YF ++ IL+++L++ +E P L DIL + +FT +F
Sbjct: 652 WAGLRIKLDLIVSSRYFNRGIMIAILINTLSMGIEYHEQPQE--LTDILEISNMVFTSLF 709
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMV 1294
+EML+K LALG Y N + D +IV++
Sbjct: 710 SLEMLLKLLALGLFGYIKNPYNGFDSVIVII 740
Score = 59.3 bits (137), Expect = 1e-06
Identities = 30/83 (36%), Positives = 53/83 (63%), Gaps = 1/83 (1%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL- 1590
IV+ + F+ IM+ I +N L+M +++++Q + + +L+ NM+F +FS E LLK+ AL
Sbjct: 662 IVSSRYFNRGIMIAILINTLSMGIEYHEQPQELTDILEISNMVFTSLFSLEMLLKLLALG 721
Query: 1591 RYHYFVEPWNLFDFVVVMFSILS 1613
+ Y P+N FD V+V+ L+
Sbjct: 722 LFGYIKNPYNGFDSVIVIIRSLT 744
Score = 51.6 bits (118), Expect = 2e-04
Identities = 61/269 (22%), Positives = 111/269 (41%), Gaps = 43/269 (15%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR 1591
++ K FD +I+LFI LN +T+ L+ V L F R
Sbjct: 1032 VIGHKMFDHVILLFIFLNCITIALERPDIQPNSMVVAMGL---------------YFGHR 1076
Query: 1592 YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGI 1651
Y WN+ D ++V S++ +++S +LRV+R+ + R LR++ A G+
Sbjct: 1077 V-YLQSSWNILDGLLVFVSLVDILVSVASAGGNRIFGILRVLRLLRTLRPLRVISRAPGL 1135
Query: 1652 RTLLFALAMSLPALFNI---CLLLFLVMFIFAI---FGMSFFMHVKDKGGLDD------- 1698
+ ++ L SL + NI C F+V I + G ++ D + +
Sbjct: 1136 KLVVETLITSLRPIGNIVLICCAFFIVFGILGVQLFKGKFYYCDGLDVSNITNKTQCLEA 1195
Query: 1699 -------VYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSAT 1751
YNF Q+++ LF +S GW ++ ++ D P
Sbjct: 1196 GYRWKRRKYNFDNLGQALMSLFVLSCKDGWVSIMYDGLDAVGVDQQPKRNHDPWM----- 1250
Query: 1752 IGITYLLSYLVISFLIVINMYIAVILENY 1780
+ + +S+L+I V+NM++ V+ + Y
Sbjct: 1251 --LLFFISFLLIVSFFVLNMFVGVVEKPY 1277
Score = 46.4 bits (105), Expect = 0.008
Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 10/94 (10%)
Query: 1393 NACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIY 1452
N C +NFD++G A++ +FQV T +GW+ IM +D+ + Y
Sbjct: 238 NECRAGEINPHKGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAH----------SFY 287
Query: 1453 MYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
++Y +NL + VI F+E K++
Sbjct: 288 NFIYFIFLIIVGSFFMINLCLVVIATQFSETKQR 321
Score = 45.2 bits (102), Expect = 0.018
Identities = 19/70 (27%), Positives = 42/70 (60%), Gaps = 11/70 (15%)
Query: 349 NPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVN 397
NP+ G +FD G+A+++ F+++T + W ++ ++F+ +I +GSF+++N
Sbjct: 246 NPHKGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFIFLIIVGSFFMIN 305
Query: 398 LILAIVAMSY 407
L L ++A +
Sbjct: 306 LCLVVIATQF 315
Score = 43.6 bits (98), Expect = 0.056
Identities = 21/77 (27%), Positives = 44/77 (57%), Gaps = 3/77 (3%)
Query: 805 IVVNTLFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTF 864
++V L +LD HN+ A+++ LR + P++ +L++++ T+ LGN+
Sbjct: 73 VIVGMLEYSLDGHNVSLS---AIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLA 129
Query: 865 VLCIIIFIFAVMGMQLF 881
+ + FIF ++G+QL+
Sbjct: 130 LCFFVFFIFGIVGVQLW 146
Score = 38.7 bits (86), Expect = 1.6
Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 19/111 (17%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF-GKNYVDYVDR 891
LR ++ P L L++ + ++ +GN+ + C +F ++G+QLF GK Y Y D
Sbjct: 1123 LRPLRVISRAPGLKLVVETLITSLRPIGNIVLICCAFFIVFGILGVQLFKGKFY--YCDG 1180
Query: 892 FPDGDLP----------RW-----NFTDFMHSFMIVFRVLCGE-WIESMWD 926
++ RW NF + + M +F + C + W+ M+D
Sbjct: 1181 LDVSNITNKTQCLEAGYRWKRRKYNFDNLGQALMSLFVLSCKDGWVSIMYD 1231
>UniRef50_A0DI68 Cluster: Chromosome undetermined scaffold_51, whole
genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_51, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 2039
Score = 148 bits (359), Expect = 1e-33
Identities = 146/640 (22%), Positives = 292/640 (45%), Gaps = 44/640 (6%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEM 1267
R+ K I + F + + + + + LA++ + + I+ ++ + + TV M
Sbjct: 1155 RILCVKTIRSEIFYWSRLGLNIGFIVLLAIQTYQVEYMVIVDSLILITNLLITVQTI--M 1212
Query: 1268 LIKWLALGFQK--YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLR 1325
LI L L +K Y + W D + ++ + + + LR LRP +
Sbjct: 1213 LIIALGLIHEKGTYIQHVWQITDIMYLVCYYLQLINTES-----RILHLFLYLRYLRPFK 1267
Query: 1326 AMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLS 1385
+ + + + N+LV A+ ++ NVL+ LI W +FA+ G+ L+ K+ C D+ +
Sbjct: 1268 LLYSFKPIVKLYNSLVAALYNMSNVLITLLIIWTMFAVYGMILYQNKFGFCDDL----MQ 1323
Query: 1386 HEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQP 1445
EI +K C E W NFD++ A LF ++TF GW +I+ A +SR + P
Sbjct: 1324 FEI--NKQQCEDEGRRWITYQHNFDNITVALPTLFVISTFDGWGEILQVAENSRPSYQGP 1381
Query: 1446 IRETN-IYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYN 1504
N + Y+Y L+LF G++ N ++K +T Q+++
Sbjct: 1382 FPFANQLPTYIYLTLFCFIGSMFFLSLFTGLLFLNLKASQQKIEYD---DLTVYQQEFIQ 1438
Query: 1505 AMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETF 1564
+K+ P + P PR + I ++ ++ F + L + L+ + + + YQ +
Sbjct: 1439 ISQKILRDSPSFSQP-PRNIIRRIAQKLNSNSYFQYLSFLILILDTI-IQMSFYQDMDVE 1496
Query: 1565 SAV-LDYLNMIFIVIFSSECLLKIFALRYHYFV-EPWNLF-DFVVV--MFSILSLVLSDI 1619
A+ L+ + I V+F+ ++++ + F+ + W LF F+V+ MF +++ D+
Sbjct: 1497 VALELNKFHEIISVLFTFWVIVQLLDYGFKRFIDDQWRLFYSFIVIISMFELIATQKYDL 1556
Query: 1620 IEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIF 1679
+ F S ++ ++ +L L KG ++ L+ + S P L I +L + +
Sbjct: 1557 FKIQFTSTMFTENYQIIRL-LILILFKGFDDLQRLIRVMIFSFPFLGKILFILIVTTLSY 1615
Query: 1680 AIFGMSFFMHVKDKGG-LDDVYNFKTFVQSMILLFQMSTSAGWDGVL-DGIINEEECDLP 1737
A+ G F H+ DKG +D NF TF S++ L + + + ++ D +I+ C
Sbjct: 1616 ALLGCQLFGHI-DKGVIIDSQINFSTFTSSLLTLLKCGSCDNFRSIMTDTMIHNIYC--- 1671
Query: 1738 DNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQ--ATEDVQEGLTDDD 1795
P CGS I Y +S++ IS +++N+++ ++E + + +E+ + +
Sbjct: 1672 ---YDDPRYCGSQFAQI-YFISFVFISNYVLLNLFVLGLIEQFEKFFQSENSILQVYIES 1727
Query: 1796 YDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHKP 1835
D +W ++ Y R+ + +L + + L+I +P
Sbjct: 1728 IDKIKTVWCKY-----SYQRHGKAMHYLQICKFLLEIGQP 1762
Score = 53.2 bits (122), Expect = 7e-05
Identities = 39/200 (19%), Positives = 96/200 (48%), Gaps = 9/200 (4%)
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKI 1587
I F I+T+K + + I +N L ++L ++ + + D+ ++ S E +LK+
Sbjct: 829 ITFIIITNKFTNFFVDCVILINFLCLSLIGIISNQFLTVIEDFTT----IVVSLELVLKL 884
Query: 1588 FALRYHYFVEPWNL-FDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVK 1646
+ + ++ L F+ ++++ + + ++ + + LLR ++ R L+ ++
Sbjct: 885 ISFQTSRLIQKDQLIFESIIILINFSEMSFRQVLNQQDIIARLLRGTKILLFHRCLKYIR 944
Query: 1647 GAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGG-LDDVYNFKTF 1705
A I + + + L+FL++ I+ + GM+ + D+ L ++++K
Sbjct: 945 MAVLIGLIA---KRTFKQYIYLTFLMFLMILIYGLLGMAVYASSFDETTLLGHLHSYKDP 1001
Query: 1706 VQSMILLFQMSTSAGWDGVL 1725
++S + +F + T+ W GVL
Sbjct: 1002 LKSWMTVFNIMTNDDWYGVL 1021
Score = 47.2 bits (107), Expect = 0.005
Identities = 61/288 (21%), Positives = 117/288 (40%), Gaps = 51/288 (17%)
Query: 143 FSLFIITTILVNCILMIMPTTPTVEST----EVIFTGIYTFESAVKVMARGFILQPFTYL 198
+ +F+ ILVN ++ + + E++ IY + +++++G I Y
Sbjct: 217 YKIFMSIVILVNLVIFVSKILSLDDDKFVVYEIMVIYIYIVDQLFRIISKGIIGHKHAYF 276
Query: 199 RDAWNWLDFVVIALAYVT---MGIDLGNLAALRTFRVLRAL-----KTVAIVPGLKTIVG 250
R NW D ++ L T I+ + + LR +L L GLK ++
Sbjct: 277 RVVKNWFDLILTVLQINTTLIRNIESVDFSPLRLITLLLYLGDFVPGIYTFKLGLKIMLK 336
Query: 251 AVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERF 310
++ +S K L + +I+ + FA +G ++ G++ +C+ P + L ++ W
Sbjct: 337 SLGKSFKYLIEALIIVIVFGLFFATLGQSLFHGLINYRCL---PR--QYDTLDNQPWIS- 390
Query: 311 CQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRL 370
C +S C VC Q PN TSF+ ++ R
Sbjct: 391 ----------------CRITS----CPDDLVC-QYVQSGPNIP-TSFNNIFSSYAQVLRT 428
Query: 371 MTQDYWE-----------NLYQLFFVVIIFLGSFYLVNLILAIVAMSY 407
+T D W +++++IIF G F+ NL++A++ + Y
Sbjct: 429 ITMDDWTWVMYFTLKSYGTYIWVYYLLIIFFGGFFGFNLVIAVLKIHY 476
Score = 41.5 bits (93), Expect = 0.23
Identities = 28/119 (23%), Positives = 62/119 (52%), Gaps = 5/119 (4%)
Query: 166 VESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLA 225
V+S +I + T ++ + ++A G I + TY++ W D + + Y+ + I+ +
Sbjct: 1195 VDSLILITNLLITVQTIMLIIALGLIHEKGTYIQHVWQITDIMYLVCYYLQL-INTES-R 1252
Query: 226 ALRTFRVLRALKTVAIVPGLKTIV---GAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
L F LR L+ ++ K IV +++ ++ N+ +V+I + ++FA+ G+ +Y
Sbjct: 1253 ILHLFLYLRYLRPFKLLYSFKPIVKLYNSLVAALYNMSNVLITLLIIWTMFAVYGMILY 1311
Score = 36.3 bits (80), Expect = 8.5
Identities = 36/158 (22%), Positives = 70/158 (44%), Gaps = 13/158 (8%)
Query: 779 WLWLEFQKYVALLVFDPFVELFITLCIVVNTL-FMALDHHNMDK-DMDKALKSGNY---- 832
W+ ++ Y D LF + ++++ +A +++ K + + NY
Sbjct: 1515 WVIVQLLDYGFKRFIDDQWRLFYSFIVIISMFELIATQKYDLFKIQFTSTMFTENYQIIR 1574
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
L + L K + L LI +M + LG + F+L + +A++G QLFG ++D+
Sbjct: 1575 LLILILFKGFDDLQRLIRVMIFSFPFLGKILFILIVTTLSYALLGCQLFG-----HIDKG 1629
Query: 893 PDGDLPRWNFTDFMHSFMIVFRV-LCGEWIESMWDCML 929
D + NF+ F S + + + C + M D M+
Sbjct: 1630 VIID-SQINFSTFTSSLLTLLKCGSCDNFRSIMTDTMI 1666
>UniRef50_Q06AY4 Cluster: Four domain-type voltage-gated ion channel
alpha-1 subunit; n=4; Caenorhabditis|Rep: Four
domain-type voltage-gated ion channel alpha-1 subunit -
Caenorhabditis elegans
Length = 1763
Score = 147 bits (356), Expect = 3e-33
Identities = 153/672 (22%), Positives = 301/672 (44%), Gaps = 65/672 (9%)
Query: 1252 LYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDF-----IIVMVSLINFVAALCGA 1306
L + IF ++ E+++K +A G +FT D I + ++ + F+ +
Sbjct: 937 LQIAEYIFVLVMSFELIVKCIANGL--FFTPKALVTDVGDILTIFIYITSLMFLIWMPNH 994
Query: 1307 GGIQAF-KTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMG 1365
I ++ + + RA+RPLR + + +R VV L + I V ++ ++ IFA G
Sbjct: 995 IEINSWAQLLMVCRAMRPLRVYALIPHIRRVVVELCRGFREILLVTILLVVLMFIFASFG 1054
Query: 1366 VQLFAGKYFKCVDMNHTTLSH--EIIPDKNACT-LENY---------------TWENSP- 1406
VQL GK C D T+ + + K T +E Y W N
Sbjct: 1055 VQLVGGKLASCNDPMITSRENCTGLYDVKLFVTRMEVYGKNDNLMHPSIIVPRVWTNPRN 1114
Query: 1407 MNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXX 1466
NFDH+G A L LF+ ++KGW ++ D + R G + +IY+++
Sbjct: 1115 FNFDHIGNAMLALFETLSYKGW-NVVRDVLYLRH-GAWAVLFIHIYVFI--------GCM 1164
Query: 1467 XTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRP--RWR 1524
L LF+GV++ N+ E + A +T DQ+++++ ++ +PL P+P +
Sbjct: 1165 IGLTLFVGVVVANYTENRGTA------LLTVDQRRWHDLKARLKMAQPLHVPPKPPESAK 1218
Query: 1525 PQAIVFEIVTDKKFDMIIMLFIGLNMLTMTL----DHYQQSETFSAVLDYLNMIFIVIFS 1580
+ ++++ T + F + + + +N T+ + Q +TF L ++ I ++F+
Sbjct: 1219 LRCYLYDLTTSRWFKQLFAVLVVVNSFTLVIPWNVSEEQDRKTFLLCLTVISAICNILFT 1278
Query: 1581 SECLLKIFALRYHYFVEP-WNLFDFVVVMFSILSLVLSDIIE--KYF---VSPTLLRVVR 1634
ECLLK+ A F + N DF++ + I +V + + YF ++
Sbjct: 1279 LECLLKMIAFTLSGFWQSRRNRIDFIITILGINWIVFHFLFQLPAYFAGGITEWKRLTYT 1338
Query: 1635 VAKVGRVLRL--VKGAKG-IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVK 1691
+ +LR + G K ++ L+ + MS+ I +FL++ +A G+ F VK
Sbjct: 1339 YGYLVVILRFFTIAGRKSTLKMLMLTVVMSMVRSSFIIAAMFLLVLFYANAGVVLFGMVK 1398
Query: 1692 DKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEE-CDLPDNERGSPGNCGSA 1750
+ NF+ +++++LF+ T W+ ++ + C+ +CG+
Sbjct: 1399 YGQAVGKHVNFRNGREALVVLFRSVTGEDWNDIMHDCMRAPPFCNWHPGLSYWQTDCGNY 1458
Query: 1751 TIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTD-DDYDMYYEIWQRFDPD 1809
I Y S+ +I IV+N+ +A+I+EN+S ++ L D + +W D +
Sbjct: 1459 VGAIVYFCSFYLIITYIVLNLLVAIIMENFSLFYSSEEDALLSYADIRNFQLVWNMVDIE 1518
Query: 1810 GSQYIRYDQLSDFLDVLEPPLQIHKPNK---YKIISMDIP-ICRGDMMFCVDILDALT-K 1864
+ I ++ L +L+ L+++ + +K + ++ + GD + D+L+ L+ +
Sbjct: 1519 QKRSIPVRRVKFLLRLLKGRLEVNDESDGLLFKHMCHEMERLHNGDDVSFHDVLNMLSYR 1578
Query: 1865 DFFARKGNPIEE 1876
RK +EE
Sbjct: 1579 SVDIRKSLQLEE 1590
Score = 81.4 bits (192), Expect = 2e-13
Identities = 129/624 (20%), Positives = 246/624 (39%), Gaps = 86/624 (13%)
Query: 1210 KTFKLIENTYFETAVITMILLSSLALALEDVH-LPHRPILQDILYYMDRIFTVIFFIEML 1268
K+ +L+ + V LLS ++L L + P L I+ D I T+IF E
Sbjct: 42 KSTELLHERFLRDMVRVACLLSMISLCLHTPETIKMWPPLNYIILANDVIVTLIFIGEAA 101
Query: 1269 IKWLALGF----QKYFTNAWCWLDFIIVM---VSLINFVAALCG----AGGIQAFKTMRT 1317
+ G Y + W +F +++ +S + + LC A + +
Sbjct: 102 VTINQNGLFDNQNSYLRDRWYQFEFFLLINHILSCVIHIYELCSIWFPALNFVYYPWLGA 161
Query: 1318 LRALRP------LRAMSRMQGMRVVVNALVQ-AIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
LR+ RP +R++ R + + + +++ + I NV + + F +AIMGVQLF
Sbjct: 162 LRSARPFIFLRFIRSIVRFKLPKNRIKLIIKRSSQQIQNVTIFFMFFVFSYAIMGVQLFG 221
Query: 1371 GKYFKCV----DMNHTTLSHEIIPDKNACTLENYTWENSPMN------------------ 1408
+ CV D N+ T++ IPD C+ + P N
Sbjct: 222 RLNYHCVVNGTDPNNVTIADLAIPD-TMCSQKGAGGYECPGNMVCMRLQLKPQEEGFYGQ 280
Query: 1409 FDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXT 1468
F + ++ A+ +GW+ ++ D +DS + + Y
Sbjct: 281 FSDFASSLFTVYLAASQEGWVYVLYDCLDSLP---------SFLAFFYFVTLIFFLAWLV 331
Query: 1469 LNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIP---RPRWRP 1525
N+FI VI + F E + + + Y ++K L + R
Sbjct: 332 KNVFIAVITETFAEIRVQFSEMWQTREATTDHVYTQKLEKDEDGWKLVEVDKYNRAHSNN 391
Query: 1526 QAIVFEIVTDKKFDMIIMLFIGLNML---TMTLDHYQQSETFSAVLDYLNMIFIVIFSSE 1582
+ IVT F ++ L I N + T H + + Y+ + F ++F++E
Sbjct: 392 SLFLHTIVTSTAFQTVMQLLILANAIFHATFVFYHDESDQIRKIWYYYVEVGFTILFNTE 451
Query: 1583 CLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRV 1641
++KI+A + Y + FD ++ + S L+ + F T +V R+A
Sbjct: 452 VIIKIYAFGWKAYIARGQHKFDCILCVGSSLNAIWVLYETNIF---TYFQVFRIA----- 503
Query: 1642 LRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYN 1701
RL+K + + ++ + L + + +++ + + + F +V +
Sbjct: 504 -RLIKASPMLEDFVYKIFGPGKKLGGLVIFTGILLIVTSAISLQLFCYVPK------LNK 556
Query: 1702 FKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYL 1761
F F + + +FQ+ T GW V+ I+ C NE+ P + I Y ++Y
Sbjct: 557 FTNFAVAFMSMFQIITQEGWTDVVIEILRA--C----NEQAVP------FVAI-YFVAYH 603
Query: 1762 VISFLIVINMYIAVILENYSQATE 1785
++ L V+++++AVIL+N E
Sbjct: 604 LLVTLFVLSLFVAVILDNLEMDEE 627
Score = 45.6 bits (103), Expect = 0.014
Identities = 33/126 (26%), Positives = 61/126 (48%), Gaps = 6/126 (4%)
Query: 166 VESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLD-FVVIA----LAYVTMGID 220
++ E IF + +FE VK +A G P + D + L F+ I L ++ I+
Sbjct: 937 LQIAEYIFVLVMSFELIVKCIANGLFFTPKALVTDVGDILTIFIYITSLMFLIWMPNHIE 996
Query: 221 LGNLAAL-RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQ 279
+ + A L R +R L+ A++P ++ +V + + + V IL + + +FA G+Q
Sbjct: 997 INSWAQLLMVCRAMRPLRVYALIPHIRRVVVELCRGFREILLVTILLVVLMFIFASFGVQ 1056
Query: 280 IYMGVL 285
+ G L
Sbjct: 1057 LVGGKL 1062
>UniRef50_Q6CN16 Cluster: Kluyveromyces lactis strain NRRL Y-1140
chromosome E of strain NRRL Y- 1140 of Kluyveromyces
lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
lactis strain NRRL Y-1140 chromosome E of strain NRRL Y-
1140 of Kluyveromyces lactis - Kluyveromyces lactis
(Yeast) (Candida sphaerica)
Length = 1969
Score = 147 bits (356), Expect = 3e-33
Identities = 132/598 (22%), Positives = 261/598 (43%), Gaps = 37/598 (6%)
Query: 1254 YMDRIFTVIFFIEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGI 1309
Y + +F +F IE L+K +A GF Y N W +D ++++ I+F A L G G +
Sbjct: 1169 YFEPVFVPLFTIEFLVKTIADGFIYTPNAYCLNPWNRIDLVVLIALWIDFFAWLLGNGEL 1228
Query: 1310 -QAFKTMRTLRALR--PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGV 1366
+ K + LRALR + +M+RM +V+ + L IF V + + G+
Sbjct: 1229 ARIIKAVSALRALRFLTISSMARMTFKQVMFDGLTY----IFGACAVAFSILFPYTVWGL 1284
Query: 1367 QLFAGKYFKCVD--MNHTTLSHEIIPDK-NACTLENYTWENSPMNFDHVGKAYLCLFQVA 1423
+F G+ C D +++ +E + L T+ + ++ + A+ ++++
Sbjct: 1285 NVFRGRLGVCNDGDLSYGECYNEFTNQVFHWDILMPRTYADPILHLNSFSSAFRSMYEIV 1344
Query: 1424 TFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQ 1483
+ +GW ++ + + S VG + Y ++ LN+F+ I+ N
Sbjct: 1345 SLEGWTDLLQNMMSSTGVGTPAELFASPYSGIFLILFNFLSMVFILNIFVSFIVGNNARM 1404
Query: 1484 KKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPR-WRPQA---IVFEIVTDKK-- 1537
K A ++T +K + + + P P P ++ A I + +K+
Sbjct: 1405 KGTA------YLTLAEKSWLEVKRLLSQVCP---DPMPNVFKMNAVRRICYLWAVEKRNF 1455
Query: 1538 -FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFV 1596
F +++ + L++LT+ + Q + M+ + ++ I+ +
Sbjct: 1456 YFSVLMQFMLYLHILTLLMSKDQPYGKLPTNQNIQFMVTTSFLLIQEVMHIYGKSMRLYA 1515
Query: 1597 EP-WNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLL 1655
WN+F VVVMF+ + + I++ V + R V ++G L ++ + L+
Sbjct: 1516 RKRWNIFRCVVVMFAFATNIYELIVDHVVVGISNAR--DVFQLGIFLLVIPQNDTLNELM 1573
Query: 1656 FALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQM 1715
SLP++F++ F++ ++AI F K N +T +S+ILLF+
Sbjct: 1574 NTATASLPSIFSLVYTWFILFLVYAIALNQVFGVTKLGPNTTGNINCRTVTKSLILLFRC 1633
Query: 1716 STSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAV 1775
S GW+ +++ + EE + + GS +CGS L+S+ +IS I +NM++++
Sbjct: 1634 SFGEGWNYIMNDLTIEEPFCYSEAD-GSYTDCGSKAFAYALLMSWNIISMYIFVNMFVSL 1692
Query: 1776 ILENYS---QATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPL 1830
I+E +S E+ + ++ + W+ DPDG L F+ + PL
Sbjct: 1693 IVEKFSYVYHREENKHSPASQEEVRKFKVAWREIDPDGVGQFDVAYLPKFMHSFDGPL 1750
Score = 78.2 bits (184), Expect = 2e-12
Identities = 110/539 (20%), Positives = 221/539 (41%), Gaps = 59/539 (10%)
Query: 1282 NAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALV 1341
++W L+ + + + + + ++ + + R+L A R L+ + G+ ++ AL
Sbjct: 417 SSWGRLELLSTISAWLAYGLSINDYDDVHGLRLFRSLMAFRILKLVDLDSGLVSILRALK 476
Query: 1342 QAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK-CVDMNHTTLSHEIIPDKNAC----- 1395
IP + NV + L FW+ F I+GVQ F G + CV N S D C
Sbjct: 477 YGIPELLNVGFMLLYFWVFFGILGVQTFKGSLKRQCVWFNPNDPSDYYQYDMQFCGGYLN 536
Query: 1396 --TLENYTWENSPMNFDHVGKAYLC------LFQVATFKGWIQIMNDAIDSREVGRQPIR 1447
TLE + + + + K +LC + + G I N ++S E+ I
Sbjct: 537 AETLEPMKYVFADNSEGPLAKGFLCPANSKCISNANPYNGRISFDN-IVNSMELVFV-IM 594
Query: 1448 ETNIY---MY-----------LYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEM 1493
N + MY L+ +NL I V+ +F +K +++
Sbjct: 595 SANTFTDLMYFTMDTDNMAACLFFIVSILCLTVWMVNLLIAVLYSSFEVVHEKY--TIDK 652
Query: 1494 FMTEDQKKYYNAMKKMGS--KKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNML 1551
F T+D +N +K++ K P W + I + ++ ++ +F + L
Sbjct: 653 FSTQDNYLVFN-VKRLAHLIKSKSDTTKSPAWAERGI--RLYEKLEWFFVLAIFTSICAL 709
Query: 1552 TMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL---RYHYFVEPWNLFDFVVVM 1608
H S+ + + +N I I E +L++ + + +P ++DF++
Sbjct: 710 ASMKSH--SSDQSAQDIFSVNQIVSCILVVETILRLILYCKTPWKFLAKPNYVYDFII-- 765
Query: 1609 FSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNI 1668
SI+ VLS + + T ++ + R R+V R L + + ++N+
Sbjct: 766 -SIICAVLSFNSLRISLGQTSAWLL-FFPISRFYRVVILFSVTRNLWKKVLKNAIVIWNL 823
Query: 1669 CLLLFLVMFIFAIFGMSFFMHVKDKGGLDDV-YNFKTFVQSMILLFQMSTSAGWDGVLDG 1727
FL +F+ ++ + +F D ++D + F + + + L +++++ W L
Sbjct: 824 SAFYFLFVFLASLIVLLYFDGTLDADDMEDTPFGFYSLPNAFLTLIKIASTENWTDSLYA 883
Query: 1728 IINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATED 1786
+ +R SP SA G L+ + ++S +V+N+++AVI ++ ED
Sbjct: 884 L-----------QRDSP-TLFSALFGSVLLILWFILSNFVVLNVFVAVIAASFDIEEED 930
Score = 58.4 bits (135), Expect = 2e-06
Identities = 62/236 (26%), Positives = 104/236 (44%), Gaps = 27/236 (11%)
Query: 194 PFTYLRDAWNWLDFVVIALAYVTMGI---DLGNLAALRTFRVL---RALKTVAIVPGLKT 247
P + R +W L+ + A++ G+ D ++ LR FR L R LK V + GL +
Sbjct: 411 PRAFTRSSWGRLELLSTISAWLAYGLSINDYDDVHGLRLFRSLMAFRILKLVDLDSGLVS 470
Query: 248 IVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENW 307
I+ A+ + L +V + ++ F ++G+Q + G L ++CV P D S D
Sbjct: 471 ILRALKYGIPELLNVGFMLLYFWVFFGILGVQTFKGSLKRQCVWFNPNDPSDYYQYD--- 527
Query: 308 ERFCQNETNWYG-EGGDYPLCGNSSGAGQCEPGYVCLQG----FGPNPNYGYTSFDTFGW 362
+FC N E Y NS G G++C NP G SFD
Sbjct: 528 MQFCGGYLNAETLEPMKYVFADNSE--GPLAKGFLCPANSKCISNANPYNGRISFDNIVN 585
Query: 363 AFLSAFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
+ F +M+ + + +L LFF+V I + ++VNL++A++ S+
Sbjct: 586 SMELVFVIMSANTFTDLMYFTMDTDNMAACLFFIVSILCLTVWMVNLLIAVLYSSF 641
Score = 44.4 bits (100), Expect = 0.032
Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 5/121 (4%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDL---GNLA- 225
E +F ++T E VK +A GFI P Y + WN +D VV+ ++ L G LA
Sbjct: 1171 EPVFVPLFTIEFLVKTIADGFIYTPNAYCLNPWNRIDLVVLIALWIDFFAWLLGNGELAR 1230
Query: 226 ALRTFRVLRALKTVAIVPGLK-TIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
++ LRAL+ + I + T + + + + + L + + GL ++ G
Sbjct: 1231 IIKAVSALRALRFLTISSMARMTFKQVMFDGLTYIFGACAVAFSILFPYTVWGLNVFRGR 1290
Query: 285 L 285
L
Sbjct: 1291 L 1291
>UniRef50_O42398 Cluster: Voltage-dependent L-type calcium channel
subunit alpha-1S; n=33; Euteleostomi|Rep:
Voltage-dependent L-type calcium channel subunit alpha-1S
- Gallus gallus (Chicken)
Length = 281
Score = 145 bits (351), Expect = 1e-32
Identities = 89/282 (31%), Positives = 156/282 (55%), Gaps = 12/282 (4%)
Query: 1473 IGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKA-IPRPRWRPQAIVFE 1531
+G +I F EQ + + E+ + Q Y A+K +PL+ IP+ ++ Q ++
Sbjct: 1 VGFVIVTFQEQGESEYKNCELDKNQRQCVQY-ALKA----RPLRRYIPKNPYQYQ--IWY 53
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR 1591
+VT F+ ++ I LN + + + HY QS + V D LN+ F V+F+ E +LK+ A +
Sbjct: 54 VVTSSYFEYLMFFLIMLNTICLGMQHYNQSAEMNHVSDILNVAFTVLFTLEMILKLMAFK 113
Query: 1592 YH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
YF +PWN+FDF++V+ SI+ ++LS+I + S + R+ +V R+++L+ +G
Sbjct: 114 AKGYFGDPWNVFDFLIVIGSIIDVILSEIDDPDDNSRVSITFFRLFRVMRLVKLLSRGEG 173
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF--MHVKDKGGLDDVYNFKTFVQS 1708
+RTLL+ S AL + LL+ ++ FI+A+ GM F + + D ++ NF+TF Q+
Sbjct: 174 VRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQA 233
Query: 1709 MILLFQMSTSAGWDGVLDGIINEEECD-LPDNERGSPGNCGS 1749
++LLF+ +T W +L + CD D G CG+
Sbjct: 234 VLLLFRCATGEAWQEILLDCSYGKRCDPESDYAEGEEYTCGT 275
Score = 72.1 bits (169), Expect = 1e-10
Identities = 38/159 (23%), Positives = 90/159 (56%), Gaps = 5/159 (3%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
++ ++YFE + +I+L+++ L ++ H + + ++ FTV+F +EM++K +A
Sbjct: 54 VVTSSYFEYLMFFLIMLNTICLGMQ--HYNQSAEMNHVSDILNVAFTVLFTLEMILKLMA 111
Query: 1274 LGFQKYFTNAWCWLDFIIVMVSLINFVAALC---GAGGIQAFKTMRTLRALRPLRAMSRM 1330
+ YF + W DF+IV+ S+I+ + + + R R +R ++ +SR
Sbjct: 112 FKAKGYFGDPWNVFDFLIVIGSIIDVILSEIDDPDDNSRVSITFFRLFRVMRLVKLLSRG 171
Query: 1331 QGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
+G+R ++ +++ ++ V L+ ++ + I+A++G+Q+F
Sbjct: 172 EGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMF 210
Score = 50.4 bits (115), Expect = 5e-04
Identities = 41/172 (23%), Positives = 80/172 (46%), Gaps = 20/172 (11%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMP-------TTPTVESTEVIFTGIYT 178
P NP + Y++ F + I++N I + M + V FT ++T
Sbjct: 43 PKNPYQYQIWYVVTSSYFEYLMFFLIMLNTICLGMQHYNQSAEMNHVSDILNVAFTVLFT 102
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLDFVVI---ALAYVTMGID------LGNLAALRT 229
E +K+MA + Y D WN DF+++ + + ID ++ R
Sbjct: 103 LEMILKLMA----FKAKGYFGDPWNVFDFLIVIGSIIDVILSEIDDPDDNSRVSITFFRL 158
Query: 230 FRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
FRV+R +K ++ G++T++ I+S + L V +L + ++A++G+Q++
Sbjct: 159 FRVMRLVKLLSRGEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMF 210
Score = 43.6 bits (98), Expect = 0.056
Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 5/96 (5%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
+R+ KL + L+ ++ AL + ++ ++ FI+AV+GMQ+FGK + VD
Sbjct: 162 MRLVKLLSRGEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGK--IAMVDGT 219
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDC 927
NF F + +++FR GE W E + DC
Sbjct: 220 QIN--RNNNFQTFPQAVLLLFRCATGEAWQEILLDC 253
>UniRef50_Q8T769 Cluster: Putative uncharacterized protein; n=1;
Branchiostoma floridae|Rep: Putative uncharacterized
protein - Branchiostoma floridae (Florida lancelet)
(Amphioxus)
Length = 754
Score = 144 bits (349), Expect = 2e-32
Identities = 77/240 (32%), Positives = 135/240 (56%), Gaps = 10/240 (4%)
Query: 1593 HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIR 1652
+YF + WN+FDF+ V+ S+ +++S+ + F+S + LR+ R A R+++L++ + IR
Sbjct: 1 NYFRDAWNVFDFITVVGSVTDILVSNFGDN-FISLSFLRLFRAA---RLIKLLRQGETIR 56
Query: 1653 TLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHV--KDKGGLDDVYNFKTFVQSMI 1710
TLL+ S AL + LL+ +++FI+AI GM F ++ D+ + NF+TF+Q ++
Sbjct: 57 TLLWTFIQSFKALPYVVLLIAMLLFIYAIVGMQVFGNIALDDETEIHRHNNFRTFIQGLM 116
Query: 1711 LLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVIN 1770
+LF+ +T W ++ + ECD + G NCGS T Y S++ + +++N
Sbjct: 117 VLFRCATGEAWQEIMLSCLPGAECDAQSEDPGP--NCGS-TFAYFYFTSFIFLCSFLMLN 173
Query: 1771 MYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPL 1830
+++AVI++N+ T D L + Y +W FDP + I Y + D L L PPL
Sbjct: 174 LFVAVIMDNFDYLTRDTSI-LGPHHLEEYIRVWADFDPGATGRISYTDMFDLLKQLNPPL 232
Score = 53.2 bits (122), Expect = 7e-05
Identities = 49/207 (23%), Positives = 90/207 (43%), Gaps = 28/207 (13%)
Query: 1279 YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVN 1338
YF +AW DFI V+ S+ + + + G I + +R RA R ++ + + + +R ++
Sbjct: 2 YFRDAWNVFDFITVVGSVTDILVSNFGDNFI-SLSFLRLFRAARLIKLLRQGETIRTLLW 60
Query: 1339 ALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLE 1398
+Q+ ++ V+L+ + I+AI+G+Q+F L+
Sbjct: 61 TFIQSFKALPYVVLLIAMLLFIYAIVGMQVFGN-----------------------IALD 97
Query: 1399 NYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRE----TNIYMY 1454
+ T + NF + + LF+ AT + W +IM + E Q + + Y
Sbjct: 98 DETEIHRHNNFRTFIQGLMVLFRCATGEAWQEIMLSCLPGAECDAQSEDPGPNCGSTFAY 157
Query: 1455 LYXXXXXXXXXXXTLNLFIGVIIDNFN 1481
Y LNLF+ VI+DNF+
Sbjct: 158 FYFTSFIFLCSFLMLNLFVAVIMDNFD 184
Score = 52.0 bits (119), Expect = 2e-04
Identities = 27/90 (30%), Positives = 49/90 (54%), Gaps = 5/90 (5%)
Query: 197 YLRDAWNWLDFVVIA-----LAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGA 251
Y RDAWN DF+ + + G + +L+ LR FR R +K + ++T++
Sbjct: 2 YFRDAWNVFDFITVVGSVTDILVSNFGDNFISLSFLRLFRAARLIKLLRQGETIRTLLWT 61
Query: 252 VIESVKNLRDVIILTMFSLSVFALMGLQIY 281
I+S K L V++L L ++A++G+Q++
Sbjct: 62 FIQSFKALPYVVLLIAMLLFIYAIVGMQVF 91
Score = 50.4 bits (115), Expect = 5e-04
Identities = 29/97 (29%), Positives = 53/97 (54%), Gaps = 7/97 (7%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
R+ KL + T+ L+ ++ AL + ++ +++FI+A++GMQ+FG +D
Sbjct: 44 RLIKLLRQGETIRTLLWTFIQSFKALPYVVLLIAMLLFIYAIVGMQVFGNIALD-----D 98
Query: 894 DGDLPRW-NFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
+ ++ R NF F+ M++FR GE W E M C+
Sbjct: 99 ETEIHRHNNFRTFIQGLMVLFRCATGEAWQEIMLSCL 135
>UniRef50_A7TEU5 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 2026
Score = 143 bits (346), Expect = 5e-32
Identities = 134/630 (21%), Positives = 274/630 (43%), Gaps = 34/630 (5%)
Query: 1220 FETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGF--- 1276
F +++T++L+ A H ++ Y+ F +IF +E L+K +A G
Sbjct: 1187 FFLSIVTILLVVVSCYATPLYRKNHHLGVRSWETYVQVAFLIIFSVEFLVKTIADGLAYT 1246
Query: 1277 -QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQA--FKTMRTLRALRPLRAMSRMQGM 1333
Y N W +D +V++S+ V +L A A FK LRAL+ L + +
Sbjct: 1247 PNAYLRNPWNLID-CVVLISVWIDVFSLLNADNDLAIIFKGFTALRALKCLTISNTARQT 1305
Query: 1334 RVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD--MNHTTLSHEIIPD 1391
V+V + I IF LV L F + G+ LF G+ C D +N+T E
Sbjct: 1306 FVIV--VYDGIGKIFEAGLVSLTLLFPFTVWGLNLFRGRLGVCNDGGLNYTMCYDEYSNT 1363
Query: 1392 KNAC-TLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETN 1450
L + N ++ D+ ++ L+++ + +GW+ ++ + ++S VG
Sbjct: 1364 AFKWDVLSPRVYSNPILHLDNFSNSFRSLYEIISLEGWVDLLENLMNSTGVGTPATPFAT 1423
Query: 1451 IYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMG 1510
++ LNLF+ +++N + G + ++T ++K + + K +
Sbjct: 1424 PINGMFLVLFNFLSMVFILNLFVSFVVNN---HARTVGSA---YLTAEEKSWTESKKLLS 1477
Query: 1511 SKKPLKAIPR--PRWRPQAIVFEIVTDKKF---DMIIMLFIGLNMLTMTLDHYQQSETF- 1564
P +++P + + + ++K+ + I L + +++ + Y+ ++
Sbjct: 1478 QASP-RSLPNVFEMNNRRKFFYRLTVEQKYFWYSLFIHLVLYAHVICLLAISYRGNDLIH 1536
Query: 1565 SAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKY 1623
+ +Y +V +ECL I++ + YF + W F+V+ S L I +
Sbjct: 1537 TPATNYFMFSTLVFLFNECLT-IYSYGFKLYFRKAWRTLRFLVIAISFLLTAKGFSIGRQ 1595
Query: 1624 FVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFG 1683
+ + +V ++ L L+ + LL S P + + ++ ++AI
Sbjct: 1596 --DYWFINIEQVFQLFYFLFLIPQNDMLTDLLETAMASWPTILALTYTWAILFLVYAIAL 1653
Query: 1684 MSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGI-INEEECDLPDNERG 1742
F + D NF+T ++S+I+LF+ S GW+ +++ + I+E C + D E G
Sbjct: 1654 NQVFGLTRLGPNTTDNINFRTIIKSLIVLFKCSFGEGWNYIMNDLTISEPYCFI-DAESG 1712
Query: 1743 SPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATED--VQEGLTDDDYDMYY 1800
+CGS ++S+ + S I +NM+I++I+ N+S + + + +
Sbjct: 1713 I-SDCGSKAYAYILMMSWNIFSMYIFLNMFISLIISNFSYVYRRGVSKSAVNRHEIRNFT 1771
Query: 1801 EIWQRFDPDGSQYIRYDQLSDFLDVLEPPL 1830
E W R+D +G+ + ++ L + + PL
Sbjct: 1772 EAWSRYDSEGTGTLAFEYLPKLMHSFDGPL 1801
Score = 52.4 bits (120), Expect = 1e-04
Identities = 87/409 (21%), Positives = 164/409 (40%), Gaps = 46/409 (11%)
Query: 1388 IIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIR 1447
+ P+ + C + NY N ++FD++ A +F + + + +M D +DS E+
Sbjct: 613 LCPEYSKC-VSNYNPYNGRISFDNIVNAMELVFVILSSNTFTDLMYDTMDSDEMA----- 666
Query: 1448 ETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFN------EQKKKAGGSLEMFMTEDQKK 1501
L+ LNLFI V++ +F E++K S E K
Sbjct: 667 -----ACLFFILATFVLTIWLLNLFIAVLVTSFELANQKFEEEKYKMSSSESIPVRLMKG 721
Query: 1502 YYNAMKKMGSKKPLKA-IPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQ 1560
Y+ + K L R + + F VT D+I+ + N L Y
Sbjct: 722 YWKYFQFKAKKTLLPYWATRSLKIYKRVEFFFVTLIIADLILRSLVTANTSDKLLHDYFI 781
Query: 1561 SETFSAVLDYLNMIF-IVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDI 1619
+E +++ + F +V++SS L IF + Y V+ LF ++ L+ + +
Sbjct: 782 AEKVISIILFAESSFRLVLYSSN--LWIFLTKIDYVVD---LFLAIITFVISLAEDTTPL 836
Query: 1620 IEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIF 1679
+ YF L +A R R+V + R L + + ++N+ FL ++
Sbjct: 837 SQAYF----WLSGFHIA---RFYRVVISFRFSRNLWKRVLGNRVMIWNLTTFYFLFTYLV 889
Query: 1680 AIFGMSFFMHV--KDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLP 1737
++ FF V KD+ G + T S + LF + ++ W +L +
Sbjct: 890 SVIVSVFFEGVISKDEEG-SIPFGMYTLANSFLSLFIIGSTENWTEILYSL--------- 939
Query: 1738 DNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATED 1786
+ SP N + L+ + ++S I +N++IA+I ++ E+
Sbjct: 940 --QENSP-NIFATFCSTVILIIWFILSNFIALNIFIAIISQSLRVKEEE 985
Score = 50.4 bits (115), Expect = 5e-04
Identities = 34/121 (28%), Positives = 58/121 (47%), Gaps = 5/121 (4%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYV----TMGIDLGNLA 225
+V F I++ E VK +A G P YLR+ WN +D VV+ ++ + D
Sbjct: 1223 QVAFLIIFSVEFLVKTIADGLAYTPNAYLRNPWNLIDCVVLISVWIDVFSLLNADNDLAI 1282
Query: 226 ALRTFRVLRALKTVAIV-PGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
+ F LRALK + I +T V V + + + + ++++ L F + GL ++ G
Sbjct: 1283 IFKGFTALRALKCLTISNTARQTFVIVVYDGIGKIFEAGLVSLTLLFPFTVWGLNLFRGR 1342
Query: 285 L 285
L
Sbjct: 1343 L 1343
Score = 49.2 bits (112), Expect = 0.001
Identities = 55/258 (21%), Positives = 105/258 (40%), Gaps = 29/258 (11%)
Query: 173 FTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI------DLGNLAA 226
FT T ES + P + R +WN D V ++ + + D +
Sbjct: 443 FTRTNTLESDSSDLKNAPFNCPRAFARSSWNRTDLVSSLSFWIGVFLSINKYDDKNGIRI 502
Query: 227 LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLT 286
++ +LR L+ + G+ +I+ + + L V + ++ F ++G+Q++ G
Sbjct: 503 FKSLALLRILRLLDTDTGVSSIIRGIKYGLPQLIGVGSMLVYFWVFFGILGVQVFRGSFR 562
Query: 287 QKCVKVFPEDGSWGNLTD--ENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQ 344
+KCV + P N TD EN ++C G + G G++C +
Sbjct: 563 RKCVWINP-----NNSTDIFENDGQYCGGYLE-IGTKAKKNYVFSDGTEGPASKGFLCPE 616
Query: 345 ----GFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQ-----------LFFVVIIF 389
NP G SFD A F +++ + + +L LFF++ F
Sbjct: 617 YSKCVSNYNPYNGRISFDNIVNAMELVFVILSSNTFTDLMYDTMDSDEMAACLFFILATF 676
Query: 390 LGSFYLVNLILAIVAMSY 407
+ + +L+NL +A++ S+
Sbjct: 677 VLTIWLLNLFIAVLVTSF 694
Score = 46.8 bits (106), Expect = 0.006
Identities = 25/74 (33%), Positives = 42/74 (56%), Gaps = 4/74 (5%)
Query: 1308 GIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQ 1367
GI+ FK++ LR LR L + G+ ++ + +P + V + + FW+ F I+GVQ
Sbjct: 499 GIRIFKSLALLRILRLLDTDT---GVSSIIRGIKYGLPQLIGVGSMLVYFWVFFGILGVQ 555
Query: 1368 LFAGKY-FKCVDMN 1380
+F G + KCV +N
Sbjct: 556 VFRGSFRRKCVWIN 569
>UniRef50_Q6Q762 Cluster: Four domain-type voltage-gated ion channel
alpha-1 subunit; n=7; Caenorhabditis|Rep: Four
domain-type voltage-gated ion channel alpha-1 subunit -
Caenorhabditis elegans
Length = 1831
Score = 140 bits (338), Expect = 5e-31
Identities = 134/565 (23%), Positives = 253/565 (44%), Gaps = 63/565 (11%)
Query: 1319 RALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVD 1378
RA+RPLR + + +R VV + I V ++ ++ IFA GVQ+ GK C D
Sbjct: 1008 RAMRPLRIYTLVPHIRRVVLEFFRGFKEILLVTILMIVVMFIFASFGVQIVGGKLAACND 1067
Query: 1379 MNHTTLSH--EIIPDKNACT-LENY---------------TWENSP-MNFDHVGKAYLCL 1419
++ + + K T LE Y W N NFDHVG A L L
Sbjct: 1068 PTVSSRENCTGVFWQKLFVTRLEVYGKDTEAMHPKIMVPRVWTNPRNFNFDHVGNAMLAL 1127
Query: 1420 FQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDN 1479
F+ +FKGW ++ D + SR G + +IY+++ L LF+GV+I N
Sbjct: 1128 FETLSFKGW-NVIRDILWSRH-GPWAVVFIHIYVFI--------GCMIGLTLFVGVVIAN 1177
Query: 1480 FNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRP--RWRPQAIVFEIVTDKK 1537
+ + + A +T DQ+++++ ++ +PL P+P R + ++++ +
Sbjct: 1178 YTQNRGTA------LLTVDQRRWHDLKARLKMAQPLHVPPKPSESARLRTKLYDLTMSRW 1231
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSE--------TFSAVLDYLNMIFIVIFSSECLLKIFA 1589
F+ L + LN T+ + + E T +A+ ++NM+F++ E +LK+ A
Sbjct: 1232 FNQAFALLVVLNSFTLVIPWNVEEEEQRATYVFTVTALAAFMNMLFVI----EIILKVIA 1287
Query: 1590 LRYHYFVEP-WNLFDFVVVMFSILSLVLS----------DIIEKYFVSPTLLRVVRVAKV 1638
+ F + N D ++ +F ++ + L D+ + + + +
Sbjct: 1288 YTFSGFWQSRRNRVDLLITVFGVIWIFLHFFVALPSSKIDVDVQVELKKFTYTFGYLVVI 1347
Query: 1639 GRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDD 1698
R + ++ L+ + MS+ F I LFL++ +A G+ F VK +
Sbjct: 1348 LRFFTIASRNSTLKMLMLTVIMSMFRSFFIITALFLLVLFYAYTGVILFPMVKYGMAVSK 1407
Query: 1699 VYNFKTFVQSMILLFQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYL 1757
NF+T +++++LF+ T W+ ++ D + + C + +CG+ I Y
Sbjct: 1408 HVNFRTASEALVVLFRCLTGEDWNDIMHDCMRSAPFCYWNEGMNYWETDCGNFYGAIIYF 1467
Query: 1758 LSYLVISFLIVINMYIAVILENYSQATEDVQEGLTD-DDYDMYYEIWQRFDPDGSQYIRY 1816
S+ +I IV N+ +AVI+EN+S ++ L D + +W D + + I
Sbjct: 1468 CSFYLIITYIVRNLLVAVIMENFSLFYSSEEDALLSYADIRNFQYVWNMVDQEQKRTIPV 1527
Query: 1817 DQLSDFLDVLEPPLQIHKPNKYKII 1841
+++ L +L+ L++ P K +I+
Sbjct: 1528 ERVKFLLRLLKGRLEV-DPEKDRIL 1551
Score = 73.7 bits (173), Expect = 5e-11
Identities = 106/508 (20%), Positives = 205/508 (40%), Gaps = 70/508 (13%)
Query: 1307 GGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGV 1366
G I++ + +R + PL ++ R+ L ++ + NV L + F ++AI G+
Sbjct: 158 GAIRSIRPFIIIRLI-PLVVKFKLPKNRIE-QLLKRSSQQVKNVTLFFVFFMTLYAIFGI 215
Query: 1367 QLFAGKYFKCV----DMNHTTLSHEIIPDKNACTLENYTWENSP-------MN------- 1408
QLF + CV D N+ T+ IPD C E P +N
Sbjct: 216 QLFGRMDYHCVQPKTDPNNVTIMDLAIPD-TMCAPEGIGGYECPAPMVCMQLNLNAKGEG 274
Query: 1409 ----FDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXX 1464
F+ G + ++ A+ +GW+ ++ D +DS + +LY
Sbjct: 275 FYGMFNDFGASVFTVYLAASEEGWVYVLYDCMDSL---------PSYLAFLYFCTLIFFL 325
Query: 1465 XXXTLNLFIGVIIDNFNE---QKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRP 1521
N+FI VI + F E Q + E+ + E +K L P
Sbjct: 326 AWLVKNVFIAVITETFAEIRVQFSEMWQKKEVTLDEGFRKKLEKTDDGWRLIRLDGEVEP 385
Query: 1522 RWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFS--AVLDYLNMI-FIVI 1578
Q + + ++ F +++F+ +N + + Y+ ET YL + F ++
Sbjct: 386 EGPKQKLQW-MLRSMYFQCFVIIFVVINAIGNAMFVYRHDETDKPRKYNFYLFEVGFTIL 444
Query: 1579 FSSECLLKIFALRYHYFVEPWNL-FDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAK 1637
F+ EC++KI + F+ F+ ++ + S L+ V YF R++R+ K
Sbjct: 445 FNVECIIKILCYGFRNFIRRGIFKFELILCLGSSLNCVKFFYERNYFTYFQTFRLLRLIK 504
Query: 1638 VGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLD 1697
+L + +F+ L L++F + FI +S + +
Sbjct: 505 ASPIL------EDFVWKIFSPGKKLGG-----LVIFTIAFICCYSAISLQLFY----SVP 549
Query: 1698 DVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYL 1757
++++F+TF Q+ + +FQ+ T GW + ++ + +L + Y
Sbjct: 550 NLHHFRTFPQAFMSMFQIITQEGWTDFVVEVLRATDDNL-------------VPLVALYF 596
Query: 1758 LSYLVISFLIVINMYIAVILENYSQATE 1785
++Y + LIV+++++AVIL+N E
Sbjct: 597 VAYHLFVTLIVLSLFVAVILDNLEMDEE 624
Score = 56.8 bits (131), Expect = 6e-06
Identities = 54/208 (25%), Positives = 91/208 (43%), Gaps = 21/208 (10%)
Query: 131 RRVAIYILVHPLFSLFIITTILVNCILMIM----PTTPT--------VESTEVIFTGIYT 178
+ + I + P + T +V+CI M+ PTT ++ ++ F T
Sbjct: 890 KEIRALIGIMPYIDWAMATVTIVSCISMLFESPWPTTGENLVMNNGYLQISDYFFVLSMT 949
Query: 179 FESAVKVMARGFILQPFTYLRDAWNWLD-FV----VIALAYVTMGIDLGNLAA-LRTFRV 232
FE VK++A G P +RD ++ F+ VI LA++ +++ +LA L R
Sbjct: 950 FELCVKIIANGLFFTPKAVVRDVGGVMNLFIYFTSVIFLAWMPKHVEINSLAQFLMICRA 1009
Query: 233 LRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKV 292
+R L+ +VP ++ +V K + V IL + + +FA G+QI G L C
Sbjct: 1010 MRPLRIYTLVPHIRRVVLEFFRGFKEILLVTILMIVVMFIFASFGVQIVGGKLA-ACND- 1067
Query: 293 FPEDGSWGNLTDENWERFCQNETNWYGE 320
P S N T W++ YG+
Sbjct: 1068 -PTVSSRENCTGVFWQKLFVTRLEVYGK 1094
Score = 40.3 bits (90), Expect = 0.52
Identities = 24/110 (21%), Positives = 52/110 (47%), Gaps = 1/110 (0%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRI-FTVIFFIEMLIKWL 1272
++ + YF+ VI ++++++ A+ + +Y+ + FT++F +E +IK L
Sbjct: 395 MLRSMYFQCFVIIFVVINAIGNAMFVYRHDETDKPRKYNFYLFEVGFTILFNVECIIKIL 454
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALR 1322
GF+ + + I+ + S +N V F+T R LR ++
Sbjct: 455 CYGFRNFIRRGIFKFELILCLGSSLNCVKFFYERNYFTYFQTFRLLRLIK 504
Score = 36.3 bits (80), Expect = 8.5
Identities = 33/146 (22%), Positives = 63/146 (43%), Gaps = 12/146 (8%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVI---ALAYVTMGIDLGNLAA 226
EV FT ++ E +K++ GF ++R + ++ +L V +
Sbjct: 438 EVGFTILFNVECIIKILCYGFR----NFIRRGIFKFELILCLGSSLNCVKFFYERNYFTY 493
Query: 227 LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLT 286
+TFR+LR +K I L+ V + K L ++I T+ + ++ + LQ++ V
Sbjct: 494 FQTFRLLRLIKASPI---LEDFVWKIFSPGKKLGGLVIFTIAFICCYSAISLQLFYSVPN 550
Query: 287 QKCVKVFPED--GSWGNLTDENWERF 310
+ FP+ + +T E W F
Sbjct: 551 LHHFRTFPQAFMSMFQIITQEGWTDF 576
>UniRef50_Q4SMF4 Cluster: Chromosome undetermined SCAF14551, whole
genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome undetermined SCAF14551, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 963
Score = 139 bits (336), Expect = 8e-31
Identities = 86/285 (30%), Positives = 147/285 (51%), Gaps = 12/285 (4%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
++I T F ++ ILLSS++LA ED P +L Y D +FT +F E+++K
Sbjct: 459 RIINATTFTNIILLFILLSSISLAAEDPIDP-LSFRNKVLAYADIVFTSVFTAEIVLKMT 517
Query: 1273 ALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMS 1328
G + N++ LD ++V VSL++ + I K +R LR LRPLRA++
Sbjct: 518 TYGAILHKGSFCRNSFNILDLLVVSVSLLSMGME---SNAISVVKILRVLRVLRPLRAIN 574
Query: 1329 RMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEI 1388
R +G++ VV + A+ +I N++LV ++ +FA +GVQLF + K + M
Sbjct: 575 RAKGLKHVVQCVFVAVKTIGNIVLVTMLLDFMFACIGVQLFKVRKNK-MKMFWGFFGSRA 633
Query: 1389 IPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRE 1448
+ + C E W N+ +NFD++ L LF ++TF+GW +I+ AIDS P+
Sbjct: 634 LHEMEVCKRE---WTNADLNFDNIVNGMLALFTISTFEGWPKILYKAIDSNSEDEGPLYN 690
Query: 1449 TNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEM 1493
+ + ++ +N+F+G +I F EQ ++ + E+
Sbjct: 691 NRVAISIFFIIYLILIAFFMMNIFVGFVIITFQEQGEQEYKNCEL 735
Score = 114 bits (274), Expect = 3e-23
Identities = 88/316 (27%), Positives = 155/316 (49%), Gaps = 58/316 (18%)
Query: 128 NPIRRVAIYILVHPLFSLFIITTILVNCI----LMIMP------TTPTVESTEVIFTGIY 177
NP R+ + I+ F + I+ I NC+ + MP T +ES E IF I+
Sbjct: 31 NPFRKACLSIVEWKPFEIIILLAIFANCVGLAVYLPMPEEDSNNTNSNLESLEYIFLIIF 90
Query: 178 TFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN-------------- 223
+ E +K++A GF+ YLR+ WN LDFV +++ T+ +D N
Sbjct: 91 SVECFLKIVAYGFLFHADAYLRNCWNILDFVCVSVGLFTVAVDAINHLSGVEAPIGEKGG 150
Query: 224 ---LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
+ ALR FRVLR L+ V+ VP L+ ++ ++++S+ L + +L F ++++++MGL++
Sbjct: 151 GFDMKALRAFRVLRPLRLVSGVPSLQVVMNSILKSMLPLFHITLLVFFMVTIYSIMGLEL 210
Query: 281 YMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGY 340
+ + + C + G+ T EN + + + G+ C +C G+
Sbjct: 211 FKCKMHKTCYYI----GTNIIATVEN------EKPSPCAKAGNGRRC--LINGTECRIGW 258
Query: 341 VCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWEN-LYQL-----------FFVVII 388
P PN G T FD G++ L+ ++ +T W + LY L FF +I
Sbjct: 259 -------PGPNNGITHFDNLGFSMLTVYQCITTQGWTDVLYWLNDAIGMEWPWIFFTTLI 311
Query: 389 FLGSFYLVNLILAIVA 404
+GSF+++NLIL +++
Sbjct: 312 LVGSFFVLNLILGVLS 327
Score = 83.8 bits (198), Expect = 4e-14
Identities = 79/314 (25%), Positives = 144/314 (45%), Gaps = 44/314 (14%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPI--LQDILYYMDRIFTVIFFI 1265
R ++E FE ++ I + + LA+ + +P L ++ IF +IF +
Sbjct: 34 RKACLSIVEWKPFEIIILLAIFANCVGLAVY-LPMPEEDSNNTNSNLESLEYIFLIIFSV 92
Query: 1266 EMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINF-VAALCGAGGIQA--------- 1311
E +K +A GF Y N W LDF+ V V L V A+ G++A
Sbjct: 93 ECFLKIVAYGFLFHADAYLRNCWNILDFVCVSVGLFTVAVDAINHLSGVEAPIGEKGGGF 152
Query: 1312 -FKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
K +R R LRPLR +S + ++VV+N++++++ +F++ L+ I++IMG++LF
Sbjct: 153 DMKALRAFRVLRPLRLVSGVPSLQVVMNSILKSMLPLFHITLLVFFMVTIYSIMGLELFK 212
Query: 1371 GKYFKCVDMNHTTLSHEIIPDK-NACT--------LENYT-----W---ENSPMNFDHVG 1413
K K T + + +K + C L N T W N +FD++G
Sbjct: 213 CKMHKTCYYIGTNIIATVENEKPSPCAKAGNGRRCLINGTECRIGWPGPNNGITHFDNLG 272
Query: 1414 KAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFI 1473
+ L ++Q T +GW ++ D+ +G + + +++ LNL +
Sbjct: 273 FSMLTVYQCITTQGWTDVLYWLNDA--IGME-------WPWIFFTTLILVGSFFVLNLIL 323
Query: 1474 GVIIDNFNEQKKKA 1487
GV+ F ++++KA
Sbjct: 324 GVLSGEFTKEREKA 337
Score = 74.9 bits (176), Expect = 2e-11
Identities = 35/115 (30%), Positives = 73/115 (63%), Gaps = 3/115 (2%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA--- 226
+++FT ++T E +K+ G IL ++ R+++N LD +V++++ ++MG++ ++
Sbjct: 501 DIVFTSVFTAEIVLKMTTYGAILHKGSFCRNSFNILDLLVVSVSLLSMGMESNAISVVKI 560
Query: 227 LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
LR RVLR L+ + GLK +V V +VK + +++++TM +FA +G+Q++
Sbjct: 561 LRVLRVLRPLRAINRAKGLKHVVQCVFVAVKTIGNIVLVTMLLDFMFACIGVQLF 615
Score = 72.5 bits (170), Expect = 1e-10
Identities = 52/172 (30%), Positives = 89/172 (51%), Gaps = 16/172 (9%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLD---HYQQSETFSAVLDYLNMIFIVIFSSECLLKIF 1588
IV K F++II+L I N + + + + S ++ L+ L IF++IFS EC LKI
Sbjct: 40 IVEWKPFEIIILLAIFANCVGLAVYLPMPEEDSNNTNSNLESLEYIFLIIFSVECFLKIV 99
Query: 1589 A--LRYH---YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTL--------LRVVRV 1635
A +H Y WN+ DFV V + ++ + I V + ++ +R
Sbjct: 100 AYGFLFHADAYLRNCWNILDFVCVSVGLFTVAVDAINHLSGVEAPIGEKGGGFDMKALRA 159
Query: 1636 AKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+V R LRLV G ++ ++ ++ S+ LF+I LL+F ++ I++I G+ F
Sbjct: 160 FRVLRPLRLVSGVPSLQVVMNSILKSMLPLFHITLLVFFMVTIYSIMGLELF 211
Score = 71.7 bits (168), Expect = 2e-10
Identities = 69/289 (23%), Positives = 140/289 (48%), Gaps = 40/289 (13%)
Query: 1524 RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETF-SAVLDYLNMIFIVIFSSE 1582
R + + I+ F II+LFI L+ +++ + +F + VL Y +++F +F++E
Sbjct: 452 RFRKLCHRIINATTFTNIILLFILLSSISLAAEDPIDPLSFRNKVLAYADIVFTSVFTAE 511
Query: 1583 CLLKI--FALRYH---YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAK 1637
+LK+ + H + +N+ D +VV S+LS+ + E +S +++++RV +
Sbjct: 512 IVLKMTTYGAILHKGSFCRNSFNILDLLVVSVSLLSMGM----ESNAIS--VVKILRVLR 565
Query: 1638 VGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDK---- 1693
V R LR + AKG++ ++ + +++ + NI L+ L+ F+FA G+ F K+K
Sbjct: 566 VLRPLRAINRAKGLKHVVQCVFVAVKTIGNIVLVTMLLDFMFACIGVQLFKVRKNKMKMF 625
Query: 1694 ------GGLDDV-----------YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDL 1736
L ++ NF V M+ LF +ST GW +L I+
Sbjct: 626 WGFFGSRALHEMEVCKREWTNADLNFDNIVNGMLALFTISTFEGWPKILYKAIDS----- 680
Query: 1737 PDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATE 1785
++E P I I +++ YL++ ++N+++ ++ + + E
Sbjct: 681 -NSEDEGPLYNNRVAISIFFII-YLILIAFFMMNIFVGFVIITFQEQGE 727
Score = 60.9 bits (141), Expect = 3e-07
Identities = 45/190 (23%), Positives = 88/190 (46%), Gaps = 12/190 (6%)
Query: 1664 ALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDG 1723
++F I L+ + F+ IF + F + + G + N + + L +T W
Sbjct: 696 SIFFIIYLILIAFFMMNIF-VGFVIITFQEQGEQEYKNCELDKNQVCLC---ATGEAWHE 751
Query: 1724 VLDGIINEEECD-LPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQ 1782
V+ + + CD D G CGS I Y +S+ ++ ++IN+++AVI++N+
Sbjct: 752 VMLACMYGKRCDPKSDYLPGEEYTCGS-NFAIIYFMSFYMLCAFLIINLFVAVIMDNFDY 810
Query: 1783 ATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQI-----HKPNK 1837
T D L D + +IW +DP+ + I++ + L + PL H+
Sbjct: 811 LTRD-WSILGPQHLDEFKKIWAEYDPEATGRIKHLDVVTLLRRIPAPLGFGKFCSHRIAC 869
Query: 1838 YKIISMDIPI 1847
+++SM++P+
Sbjct: 870 KRLVSMNMPL 879
Score = 40.7 bits (91), Expect = 0.40
Identities = 20/84 (23%), Positives = 38/84 (45%)
Query: 1256 DRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTM 1315
+++ +F +EM IK ALG YF + + D +V ++ + G + +
Sbjct: 380 NKLLLTMFSLEMFIKMYALGLPSYFMSLFNRFDCFVVSTGIMELILVHMGIMSVMGISVL 439
Query: 1316 RTLRALRPLRAMSRMQGMRVVVNA 1339
R +R LR L+ + ++NA
Sbjct: 440 RCIRLLRLLKVTRFRKLCHRIINA 463
Score = 40.3 bits (90), Expect = 0.52
Identities = 24/79 (30%), Positives = 43/79 (54%), Gaps = 1/79 (1%)
Query: 1569 DYLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSP 1627
D N + + +FS E +K++AL YF+ +N FD VV I+ L+L + +
Sbjct: 377 DNANKLLLTMFSLEMFIKMYALGLPSYFMSLFNRFDCFVVSTGIMELILVHMGIMSVMGI 436
Query: 1628 TLLRVVRVAKVGRVLRLVK 1646
++LR +R+ ++ +V R K
Sbjct: 437 SVLRCIRLLRLLKVTRFRK 455
Score = 37.5 bits (83), Expect = 3.7
Identities = 16/57 (28%), Positives = 38/57 (66%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
KAL++ LR +L P+L ++++ + ++M L ++T ++ ++ I+++MG++LF
Sbjct: 155 KALRAFRVLRPLRLVSGVPSLQVVMNSILKSMLPLFHITLLVFFMVTIYSIMGLELF 211
>UniRef50_UPI0000F1D26B Cluster: PREDICTED: similar to calcium
channel, voltage-dependent, alpha 1H subunit; n=1; Danio
rerio|Rep: PREDICTED: similar to calcium channel,
voltage-dependent, alpha 1H subunit - Danio rerio
Length = 741
Score = 138 bits (334), Expect = 1e-30
Identities = 80/288 (27%), Positives = 155/288 (53%), Gaps = 24/288 (8%)
Query: 1516 KAIPRPRWRPQA----IVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYL 1571
KA+ RP + + + + T D+ I + I +N+LTM+++HY+Q + L Y
Sbjct: 8 KALQRPYYADYSPTRLYIHTLCTSHYLDLFITIIIAINVLTMSMEHYRQPKYLDEGLKYC 67
Query: 1572 NMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLS--DIIEKYFVSPT 1628
N F ++F E LK+ A + +F E WN D +V+ SI+ + L D+ ++PT
Sbjct: 68 NYFFTLVFVIEAALKLVAFGFRRFFKERWNQLDLAIVLLSIMGITLEEIDLNASLPINPT 127
Query: 1629 LLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF- 1687
++R++RV ++ RVL+L+K A G+R LL + +LP + N+ LL L+ FI+A G+ F
Sbjct: 128 IIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFG 187
Query: 1688 -MHVKDKG---GLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGS 1743
+ ++ GL F+ F + + LF++ST W+G++ + E + D
Sbjct: 188 KLDCTEENPCEGLSRHATFQNFGMAFLTLFRVSTGDNWNGIMKDTLRECKND-------- 239
Query: 1744 PGNCGS--ATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQE 1789
C S + Y +++++++ +++N+ +AV++++ ++ D +E
Sbjct: 240 --KCLSYLPLLSPLYFVTFVLMAQFVLVNVVVAVLMKHLEESNIDARE 285
Score = 96.3 bits (229), Expect = 8e-18
Identities = 78/301 (25%), Positives = 136/301 (45%), Gaps = 30/301 (9%)
Query: 1199 PFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRI 1258
P++ + RL L + Y + + +I ++ L +++E P L + L Y +
Sbjct: 13 PYYADYSPTRLYIHTLCTSHYLDLFITIIIAINVLTMSMEHYRQPK--YLDEGLKYCNYF 70
Query: 1259 FTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGI-----QAFK 1313
FT++F IE +K +A GF+++F W LD IV++S++ +
Sbjct: 71 FTLVFVIEAALKLVAFGFRRFFKERWNQLDLAIVLLSIMGITLEEIDLNASLPINPTIIR 130
Query: 1314 TMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
MR LR R L+ + GMR +++ +VQA+P + N+ L+ ++ + I+A +GV+LF GK
Sbjct: 131 IMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELF-GK- 188
Query: 1374 FKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMN 1433
C ++N C E + + NF G A+L LF+V+T W IM
Sbjct: 189 LDCT-------------EENPC--EGLSRHATFQNF---GMAFLTLFRVSTGDNWNGIMK 230
Query: 1434 DAIDSREVGRQP-IRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLE 1492
D + RE + + LY +N+ + V++ + E A E
Sbjct: 231 DTL--RECKNDKCLSYLPLLSPLYFVTFVLMAQFVLVNVVVAVLMKHLEESNIDAREEAE 288
Query: 1493 M 1493
M
Sbjct: 289 M 289
Score = 49.2 bits (112), Expect = 0.001
Identities = 31/97 (31%), Positives = 52/97 (53%), Gaps = 4/97 (4%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
RV KL K + L+ + + + +GNL + ++ FI+A +G++LFGK +D + P
Sbjct: 139 RVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGK--LDCTEENP 196
Query: 894 DGDLPRW-NFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
L R F +F +F+ +FRV G+ W M D +
Sbjct: 197 CEGLSRHATFQNFGMAFLTLFRVSTGDNWNGIMKDTL 233
Score = 41.9 bits (94), Expect = 0.17
Identities = 17/46 (36%), Positives = 29/46 (63%)
Query: 787 YVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGNY 832
Y+ L +++LFIT+ I +N L M+++H+ K +D+ LK NY
Sbjct: 24 YIHTLCTSHYLDLFITIIIAINVLTMSMEHYRQPKYLDEGLKYCNY 69
>UniRef50_A0BDK4 Cluster: Chromosome undetermined scaffold_100, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_100, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 2153
Score = 137 bits (332), Expect = 2e-30
Identities = 119/525 (22%), Positives = 232/525 (44%), Gaps = 32/525 (6%)
Query: 1212 FKLIENTYFETAVITMI---LLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEML 1268
F + EN +F++ +I ++ L++ + + D + + +I+ + + +I I +
Sbjct: 1235 FSITENRFFQSLMILILWGSLINLIVITYTDQYRHEEWGICEIIKLICNLIILIDGILQI 1294
Query: 1269 IKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMS 1328
I + L YF + W ++DF+ ++ ++ A +A + M L LRPL+ S
Sbjct: 1295 ITYGLLSEDGYFNSIWVFIDFVYIICYFLHI------ATQHEALEWMLFLGYLRPLKVTS 1348
Query: 1329 RMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEI 1388
A+++++ I ++ V L+FW IFAI G+ ++ GK C + + +S
Sbjct: 1349 TYGFFINERGAIMKSLGDIISIFYVVLLFWFIFAIFGMTIYRGKMGYCGEATNYGVS--- 1405
Query: 1389 IPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRE 1448
K C E W NFD++ +A L+ ++TF W Q + I+S PIR
Sbjct: 1406 ---KEECEEEKEEWIVYQYNFDNILEAMKSLYVLSTFDLWAQTLFICINSAPETTGPIRF 1462
Query: 1449 TNIYM-YLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMK 1507
N ++ YL+ L F GVI NF + K + L +T DQ+ +
Sbjct: 1463 NNEWISYLFFFSFTFVGTLFFLQFFAGVIFVNFQQNKSQL---LNPDLTLDQELFLKLSD 1519
Query: 1508 KMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAV 1567
+ P + P P+ + +++++ + + + +N+ + L + S + +
Sbjct: 1520 IIMQDTPNYSKP-PKKGIRLGAKKLLSNSYYIFVTKYSLLINLFILMLLYESASNHYLNI 1578
Query: 1568 LDYLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFV- 1625
L+ F +I + +C++K+F+L YF + W + V+ +I+ L DI F+
Sbjct: 1579 LNGFQHFFSLILTIDCVVKLFSLNIKRYFDDVWRQMQLIFVICAIIDFFL-DIQHSIFIR 1637
Query: 1626 -------SP--TLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVM 1676
P LR+ + + R+ +++ IR LL + + AL I L V+
Sbjct: 1638 YVRASRDDPYFVWLRLFILHRCLRMALIIQQFTRIRKLLNVIYFNKMALLRILGLFVTVL 1697
Query: 1677 FIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGW 1721
++ G F ++ ++D NF F +I+ F+ + GW
Sbjct: 1698 SCYSYIGCELFSDIETGFMMNDQQNFTNFFYGLIVTFKCTIENGW 1742
Score = 55.2 bits (127), Expect = 2e-05
Identities = 44/194 (22%), Positives = 88/194 (45%), Gaps = 7/194 (3%)
Query: 1533 VTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY 1592
+T + +II F+ ++ L + Y S + D+ ++ ++ E L+K ++
Sbjct: 936 ITQQFVMVIIDSFVCIDTLLIAFSDYYDS----GISDFFDLSVNILLVLEILIKSICIK- 990
Query: 1593 HYFVEPWNLFDFVVVMFSILSLVLS-DIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGI 1651
Y + N+ +V+M S + +L+ I + V +R+ K R++K
Sbjct: 991 GYLYKVSNILGCLVIMISAIERILTLTIYQDEEVLIESFTYIRILKSLFFFRVIKYNTFA 1050
Query: 1652 RTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMIL 1711
+ ++ + P + LLLF ++ +A+F + F + D G L + F QS I
Sbjct: 1051 QNMMVISYQTFPNYAMMTLLLFFLILNYAVFSLQIF-NFPDSGELALFHYFGNIYQSWIA 1109
Query: 1712 LFQMSTSAGWDGVL 1725
++ +STS W GV+
Sbjct: 1110 VYDISTSDDWYGVV 1123
Score = 43.6 bits (98), Expect = 0.056
Identities = 35/153 (22%), Positives = 78/153 (50%), Gaps = 10/153 (6%)
Query: 143 FSLFIITTILVNCILMIMPTTPT---VESTEVIFTGIYTFESAVKVMARGFILQPFTYLR 199
F L+ + L N IL + ++ ++S + I +Y +S + + +GF Y+
Sbjct: 290 FDLYEMFLTLTNIILFLNRSSTQQNEIQSYQYILCALYFADSLIHLAGQGFK----KYIS 345
Query: 200 DAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPG-LKTIVGAVIESVKN 258
WN D +++ L ++ + + + TFR++R V + L ++ ++ E+VK
Sbjct: 346 SFWNIYDLIILILYFLFLIENDYIPFDVSTFRLIRIPFYVGKISSTLNIMLMSIQEAVKQ 405
Query: 259 L-RDVIILTMFSLSVFALMGLQIYMGVLTQKCV 290
+ +++IL +F++ + AL+ L + GV+ +C+
Sbjct: 406 IVENILILILFTILI-ALIMLYAFNGVIRYRCM 437
Score = 38.3 bits (85), Expect = 2.1
Identities = 23/122 (18%), Positives = 58/122 (47%), Gaps = 6/122 (4%)
Query: 1258 IFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRT 1317
I ++F + LI GF+KY ++ W D II+++ + + + F+ +R
Sbjct: 322 ILCALYFADSLIHLAGQGFKKYISSFWNIYDLIILILYFLFLIENDYIPFDVSTFRLIRI 381
Query: 1318 LRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKC 1376
P + +++ ++ +A+ I +L+ ++F ++ A++ + F G ++C
Sbjct: 382 -----PFYVGKISSTLNIMLMSIQEAVKQIVENILILILFTILIALIMLYAFNGVIRYRC 436
Query: 1377 VD 1378
++
Sbjct: 437 MN 438
Score = 37.5 bits (83), Expect = 3.7
Identities = 25/117 (21%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
Query: 167 ESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA 226
E ++I I + ++++ G +L Y W ++DFV I ++ + L
Sbjct: 1276 EIIKLICNLIILIDGILQIITYG-LLSEDGYFNSIWVFIDFVYIICYFLHIATQHEALEW 1334
Query: 227 LRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
+ LR LK + GA+++S+ ++ + + + +FA+ G+ IY G
Sbjct: 1335 MLFLGYLRPLKVTSTYGFFINERGAIMKSLGDIISIFYVVLLFWFIFAIFGMTIYRG 1391
>UniRef50_A0BZH6 Cluster: Chromosome undetermined scaffold_139, whole
genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_139, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 1791
Score = 136 bits (329), Expect = 6e-30
Identities = 123/525 (23%), Positives = 240/525 (45%), Gaps = 37/525 (7%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYY---MDRIFTVIFF 1264
R+ ++I + +F + T++ S + AL+ + D +Y + I +IF
Sbjct: 1273 RIICCRIITSKFFNYFIDTVLYFSIVVFALKT----YNDYESDSSFYPEVLQFIANIIFL 1328
Query: 1265 IEMLIKWLALGFQK----YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRA 1320
+E++ +A G Y T W +D I ++ +NF++ + ++ + R
Sbjct: 1329 LEIIFGSIAKGMWMNKGAYITYTWQIVDVIYIISFFLNFLSNQNKSIIVELILYLGYFRV 1388
Query: 1321 LRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMN 1380
++ + +S + +R+ AL +++ I+NVL+ L W+IF + G+ L+ ++ C D
Sbjct: 1389 MKLMYRISWLDTLRL---ALGRSLADIWNVLITMLSVWIIFGVYGIILYEQQFGFCEDK- 1444
Query: 1381 HTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSRE 1440
+ E+ +K C +N TW N NFD++ A LF V+TF GW +IM + +S+
Sbjct: 1445 ---MQFEV--NKRECLEQNRTWINYKHNFDNITIAIPTLFVVSTFDGWGEIMQISENSQN 1499
Query: 1441 VGRQPIR-ETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMF-MTED 1498
P + I+ Y + L+LF GV+ N + K +EM +T+
Sbjct: 1500 PNIGPEAFNSYIHTYTFFITFCFIGSMFFLSLFTGVLYSNLKANQSK----IEMSDITKA 1555
Query: 1499 QKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHY 1558
Q ++ + + PL + P P + + ++ I+ + L+++ + L
Sbjct: 1556 QVEFMEISQIIIKDFPLYSSP-PTSKIRRFASDLTNSNTAQKIMFCLLLLDLMVLLLFFS 1614
Query: 1559 QQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVL- 1616
+ + F +L+ + I+ +L FAL + +F W F F +++ +I+ ++
Sbjct: 1615 EMDDNFFRILNSTHNSLTYIYIIWNILLFFALGVNRFFDNHWRRFYFFLILIAIIDIIAD 1674
Query: 1617 --SDIIEKYF-VSPT-----LLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNI 1668
SD YF SP LLR+ + R++ + +G ++ L+ + ++P L I
Sbjct: 1675 FESDWALVYFRSSPADSGYQLLRLFFAIRCLRIILIFQGLINLQRLMRVMVFAMPFLGKI 1734
Query: 1669 CLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLF 1713
LL + M+IFA+FG + ++ +DD NF+ S L F
Sbjct: 1735 FCLLIITMYIFALFGCQLYGRLEKGQVMDDQINFQNVGLSHALPF 1779
Score = 47.6 bits (108), Expect = 0.003
Identities = 44/197 (22%), Positives = 92/197 (46%), Gaps = 14/197 (7%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVE 1597
FD +I++ N ++L S T S D ++ IF+ I E +++ FA + +
Sbjct: 948 FDSVILI----NFTFLSLQGIADSVTISNEED-VSTIFLCI---ELVIRFFAFSFKDISQ 999
Query: 1598 -PWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLF 1656
P + +V+ + + L +S ++ ++ LR++R K R++K K +
Sbjct: 1000 SPDYVLQSCIVILNFIELTMSSVMTN--LNEQNLRLIRGTKCLLFYRVLKYNKMAVAIGH 1057
Query: 1657 ALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDK-GGLDDVYNFKTFVQSMILLFQM 1715
+ + L FLV+F++A+ GM + D+ L ++++ +++ + +F +
Sbjct: 1058 IAQRTFRQYIYLTFLFFLVIFVYAMIGMEMYAGYFDQTDALGQLHSYDNILKAFMTIFNI 1117
Query: 1716 STSAGWDG--VLDGIIN 1730
T+ W G V+ G IN
Sbjct: 1118 LTNDDWYGVYVMGGNIN 1134
Score = 45.6 bits (103), Expect = 0.014
Identities = 46/189 (24%), Positives = 83/189 (43%), Gaps = 16/189 (8%)
Query: 1255 MDRIFTVIFFIEMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQ 1310
M+ + F IE+ I+ LA G +F N D I+V+V ++N +
Sbjct: 328 METAIMICFLIELGIRILASGVLIPKGAFFKNFQDLFDCILVVVYVLNINYPDVFIVDVS 387
Query: 1311 AFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
+ + L L + G+ V++ AL Q+ + L++ +F L FAI GV LF
Sbjct: 388 PLRVITLLLYLGDI-----FSGLGVMLKALKQSFRFLLEALMIVGLFSLFFAITGVFLFQ 442
Query: 1371 GKY-FKCVDMNHTTLSHEIIPDKNACTLENYTWENS------PMNFDHVGKAYLCLFQVA 1423
G + ++C N + ++N+C E + + S P +F++V +Y + +
Sbjct: 443 GLFNYRCQYDNGDETDGWVQCNQNSCYEEGMSCKYSSFTPKLPTSFNNVVYSYGQVLRTI 502
Query: 1424 TFKGWIQIM 1432
T W +M
Sbjct: 503 TMDDWSWVM 511
Score = 36.7 bits (81), Expect = 6.4
Identities = 28/119 (23%), Positives = 58/119 (48%), Gaps = 8/119 (6%)
Query: 804 CIVVNT---LFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALG 860
CIV+ L M+ N+++ + ++ L +++ K + I RT
Sbjct: 1008 CIVILNFIELTMSSVMTNLNEQNLRLIRGTKCLLFYRVLKYNKMAVAIGHIAQRTFRQYI 1067
Query: 861 NLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE 919
LTF+ ++IF++A++GM+++ Y D D G L ++ + + +FM +F +L +
Sbjct: 1068 YLTFLFFLVIFVYAMIGMEMYA-GYFDQTDAL--GQL--HSYDNILKAFMTIFNILTND 1121
>UniRef50_Q23DY9 Cluster: Cation channel family protein; n=2;
Alveolata|Rep: Cation channel family protein -
Tetrahymena thermophila SB210
Length = 3198
Score = 135 bits (327), Expect = 1e-29
Identities = 82/299 (27%), Positives = 157/299 (52%), Gaps = 12/299 (4%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+R + +++N F+ ++ I+L+S+ L + D + + +D +FTV F IE
Sbjct: 2069 IRRAFYFIVKNPLFDNIILAGIILNSVKL-VSDTYDTGSDSQKQASQILDIMFTVFFSIE 2127
Query: 1267 MLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALR 1322
+K ++ GF Y + W LDF +V+ S+I+ G + K +R LR LR
Sbjct: 2128 SCLKIVSYGFFFDENSYLRDNWSKLDFFVVVTSIIDVSLQ---NGNFASLKILRLLRTLR 2184
Query: 1323 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHT 1382
PLR + + M+++V L+++I I N+LLV + WL+FAI+GV L GK C + +
Sbjct: 2185 PLRVLHHNKSMKLIVTTLLESIVGILNMLLVIFLVWLMFAILGVSLMGGKLQYC-NFPNN 2243
Query: 1383 TLSHEIIP-DKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREV 1441
+S+ I +++ C+ +W+ +NFD+V A L LF ++TF+GW + + +D
Sbjct: 2244 GISYNIYKYNQSQCSRVGGSWQTYDLNFDNVPAALLNLFVISTFEGWPAYVFNYLDGSSD 2303
Query: 1442 GRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQK 1500
G P+ + Y +Y +++LF V+ +++ +K L+++++ +++
Sbjct: 2304 G--PVYFGSAYFSIYIVFFILVGSFFSIDLFGAVLSFHYDIALQKIETRLQLYLSPNKQ 2360
Score = 127 bits (307), Expect = 3e-27
Identities = 84/292 (28%), Positives = 149/292 (51%), Gaps = 34/292 (11%)
Query: 135 IYILVHPLFSLFIITTILVNCILMIM--PTTPTVEST----EVIFTGIYTFESAVKVMAR 188
I+ + + F + IL NC+++ M PTT + ++I +YT E K++A
Sbjct: 185 IWSIKNKPFEYATLCVILFNCVILAMDDPTTNADDQQRLQIDLILLILYTVEMGFKILAL 244
Query: 189 GFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLG--NLAALRTFRVLRALKTVAIVPGLK 246
GFI +Y+RD WN LD +I Y+ ++ NL+A+R+ RVLR L+T++ + LK
Sbjct: 245 GFIFNKGSYMRDMWNILDITIIITGYLPYVVNTSQVNLSAVRSLRVLRPLRTISRIKALK 304
Query: 247 TIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDEN 306
I+ + S L+D II+ +F VFA+ G Q++ G L ++C D S N
Sbjct: 305 QILNTLFSSFSLLKDAIIIIIFFYLVFAIAGQQLFTGCLKKRCF-----DSS-------N 352
Query: 307 WERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLS 366
+F N+ N + D + + Y+C +G +P + +FDTFGWA L+
Sbjct: 353 GIQFGDNDQNVFLCIEDIDCYQYAESNSKIH--YICGKGM-VSPFWDTENFDTFGWALLN 409
Query: 367 AFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
+ +++Q+ W + ++F++ + +G+ +L NL++AI+ + Y
Sbjct: 410 VYVVVSQEGWSTIQAQVQQTFGYPSFIYFMICVLVGNMFLENLLMAIIQIKY 461
Score = 97.5 bits (232), Expect = 3e-18
Identities = 57/209 (27%), Positives = 112/209 (53%), Gaps = 14/209 (6%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTE--------V 171
+L+I N IRR +I+ +PLF I+ I++N + ++ T T ++ +
Sbjct: 2059 SLYIFSMQNKIRRAFYFIVKNPLFDNIILAGIILNSVKLVSDTYDTGSDSQKQASQILDI 2118
Query: 172 IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFR 231
+FT ++ ES +K+++ GF +YLRD W+ LDF V+ + + + + GN A+L+ R
Sbjct: 2119 MFTVFFSIESCLKIVSYGFFFDENSYLRDNWSKLDFFVVVTSIIDVSLQNGNFASLKILR 2178
Query: 232 VLRALKTVAIV---PGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQK 288
+LR L+ + ++ +K IV ++ES+ + +++++ +FA++G+ + MG Q
Sbjct: 2179 LLRTLRPLRVLHHNKSMKLIVTTLLESIVGILNMLLVIFLVWLMFAILGVSL-MGGKLQY 2237
Query: 289 CVKVFPEDGSWGNLTDENWERFCQNETNW 317
C FP +G N+ N + + +W
Sbjct: 2238 C--NFPNNGISYNIYKYNQSQCSRVGGSW 2264
Score = 95.1 bits (226), Expect = 2e-17
Identities = 51/154 (33%), Positives = 87/154 (56%), Gaps = 5/154 (3%)
Query: 1549 NMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVV 1607
N+++M L + ++ +L +N+ F ++F +ECLLK+ A ++ YF + N FDF VV
Sbjct: 2366 NIVSMALSYDTSPSSYDTILQDINLGFSIVFITECLLKLIAYGFNGYFYKSSNQFDFFVV 2425
Query: 1608 MFSILSLVLS----DIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLP 1663
S++ ++ + I+ P + R+ RV +V R+LRL+K +G++ L+ L +LP
Sbjct: 2426 SVSVIDIIFTYSGNQFIKFLSAGPQIARIFRVFRVTRLLRLIKQFEGLQKLMSTLIYALP 2485
Query: 1664 ALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLD 1697
+L N LLFL+ FIFAI + + G D
Sbjct: 2486 SLTNATALLFLIYFIFAILACYLYSPYQMSTGED 2519
Score = 83.0 bits (196), Expect = 7e-14
Identities = 57/184 (30%), Positives = 94/184 (51%), Gaps = 15/184 (8%)
Query: 1206 TLRLKTFKLI---ENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVI 1262
TL K FK I +N FE A + +IL + + LA++D P +D I ++
Sbjct: 176 TLPRKIFKQIWSIKNKPFEYATLCVILFNCVILAMDD---PTTNADDQQRLQIDLILLIL 232
Query: 1263 FFIEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTL 1318
+ +EM K LALGF Y + W LD I++ + +V +R+L
Sbjct: 233 YTVEMGFKILALGFIFNKGSYMRDMWNILDITIIITGYLPYVVNTSQVN----LSAVRSL 288
Query: 1319 RALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK-CV 1377
R LRPLR +SR++ ++ ++N L + + + +++ + F+L+FAI G QLF G K C
Sbjct: 289 RVLRPLRTISRIKALKQILNTLFSSFSLLKDAIIIIIFFYLVFAIAGQQLFTGCLKKRCF 348
Query: 1378 DMNH 1381
D ++
Sbjct: 349 DSSN 352
Score = 72.1 bits (169), Expect = 1e-10
Identities = 43/146 (29%), Positives = 77/146 (52%), Gaps = 11/146 (7%)
Query: 1232 SLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFII 1291
S+AL+ + + ILQDI + F+++F E L+K +A GF YF + DF +
Sbjct: 2369 SMALSYDTSPSSYDTILQDI----NLGFSIVFITECLLKLIAYGFNGYFYKSSNQFDFFV 2424
Query: 1292 VMVSLINFVAALCG-------AGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAI 1344
V VS+I+ + G + G Q + R R R LR + + +G++ +++ L+ A+
Sbjct: 2425 VSVSVIDIIFTYSGNQFIKFLSAGPQIARIFRVFRVTRLLRLIKQFEGLQKLMSTLIYAL 2484
Query: 1345 PSIFNVLLVCLIFWLIFAIMGVQLFA 1370
PS+ N + + + IFAI+ L++
Sbjct: 2485 PSLTNATALLFLIYFIFAILACYLYS 2510
Score = 69.7 bits (163), Expect = 7e-10
Identities = 74/291 (25%), Positives = 132/291 (45%), Gaps = 46/291 (15%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQ-SETFSAVLDYLNMIFIVIFSSECLLKIFAL 1590
IV + FD II+ I LN + + D Y S++ L+++F V FS E LKI +
Sbjct: 2076 IVKNPLFDNIILAGIILNSVKLVSDTYDTGSDSQKQASQILDIMFTVFFSIESCLKIVSY 2135
Query: 1591 RYH-----YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLV 1645
+ Y + W+ DF VV+ SI+ + L + F S +LR++R R LR++
Sbjct: 2136 GFFFDENSYLRDNWSKLDFFVVVTSIIDVSLQN---GNFASLKILRLLRTL---RPLRVL 2189
Query: 1646 KGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSF------FMHVKDKGGLDDV 1699
K ++ ++ L S+ + N+ L++FLV +FAI G+S + + + G ++
Sbjct: 2190 HHNKSMKLIVTTLLESIVGILNMLLVIFLVWLMFAILGVSLMGGKLQYCNFPNNGISYNI 2249
Query: 1700 Y-------------------NFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNE 1740
Y NF +++ LF +ST GW + + D
Sbjct: 2250 YKYNQSQCSRVGGSWQTYDLNFDNVPAALLNLFVISTFEGWPAYVFNYL--------DGS 2301
Query: 1741 RGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGL 1791
P GSA I Y++ ++++ I+++ AV+ +Y A + ++ L
Sbjct: 2302 SDGPVYFGSAYFSI-YIVFFILVGSFFSIDLFGAVLSFHYDIALQKIETRL 2351
Score = 62.5 bits (145), Expect = 1e-07
Identities = 56/230 (24%), Positives = 107/230 (46%), Gaps = 28/230 (12%)
Query: 1570 YLNMIFIVIFSSECLLKI--------FALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIE 1621
Y N+I I + + +L + FAL Y + N+FD ++V+ SI ++
Sbjct: 1684 YENLIMIAVVMNTVILSLDGSVDSLGFAL---YCADRMNIFDGLIVILSIFDIIFLSGSS 1740
Query: 1622 --KYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIF 1679
F + LR++RV +V RV RL++ K ++ L+ ++ L LF I LLL L +FI+
Sbjct: 1741 GGSSFSAFRSLRILRVFRVLRVTRLLRSLKFMKILIKVISSILDKLFYIILLLILYIFIY 1800
Query: 1680 AIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDN 1739
+ GM + + F +F+Q+ ++ + T W+ +L + +
Sbjct: 1801 TLIGMQLYGGSFLSVSRSNRMVFDSFLQASFSVYDLLTIENWNNILYVALRTQV------ 1854
Query: 1740 ERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQE 1789
N G I YL+S + I I++N+ +A ++ ++ + D ++
Sbjct: 1855 ------NVGITCI---YLISCIFIGNFIIMNLVLATMIGAFNSSQFDKEK 1895
Score = 57.2 bits (132), Expect = 4e-06
Identities = 32/137 (23%), Positives = 74/137 (54%), Gaps = 7/137 (5%)
Query: 1242 LPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSL--INF 1299
L P+ ++++ + TVI ++ + +LGF Y + D +IV++S+ I F
Sbjct: 1678 LVQTPLYENLIMIAVVMNTVILSLDGSVD--SLGFALYCADRMNIFDGLIVILSIFDIIF 1735
Query: 1300 VAALCGAGGIQAFKTMRTLRALRPLRA---MSRMQGMRVVVNALVQAIPSIFNVLLVCLI 1356
++ G AF+++R LR R LR + ++ M++++ + + +F ++L+ ++
Sbjct: 1736 LSGSSGGSSFSAFRSLRILRVFRVLRVTRLLRSLKFMKILIKVISSILDKLFYIILLLIL 1795
Query: 1357 FWLIFAIMGVQLFAGKY 1373
+ I+ ++G+QL+ G +
Sbjct: 1796 YIFIYTLIGMQLYGGSF 1812
Score = 44.0 bits (99), Expect = 0.042
Identities = 48/219 (21%), Positives = 97/219 (44%), Gaps = 20/219 (9%)
Query: 1476 IIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEI--V 1533
+I +F EQ+ + L + E+Q K+ + ++ +K K P+ I +I +
Sbjct: 134 LIHSFQEQEAEF---LALKEKEEQNKFLDIVEMNEYQKIQKF--NADTLPRKIFKQIWSI 188
Query: 1534 TDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY- 1592
+K F+ + I N + + +D + L +++I +++++ E KI AL +
Sbjct: 189 KNKPFEYATLCVILFNCVILAMDDPTTNADDQQRLQ-IDLILLILYTVEMGFKILALGFI 247
Query: 1593 ----HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGA 1648
Y + WN+ D +++ L V + V+ + +R +RV + R + +K
Sbjct: 248 FNKGSYMRDMWNILDITIIITGYLPYV----VNTSQVNLSAVRSLRVLRPLRTISRIKAL 303
Query: 1649 KGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
K I LF+ S L + +++ +FAI G F
Sbjct: 304 KQILNTLFS---SFSLLKDAIIIIIFFYLVFAIAGQQLF 339
Score = 39.5 bits (88), Expect = 0.91
Identities = 18/62 (29%), Positives = 37/62 (59%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKN 884
+ L+ LRV +L +S + +LI ++ + L + +L + IFI+ ++GMQL+G +
Sbjct: 1752 RILRVFRVLRVTRLLRSLKFMKILIKVISSILDKLFYIILLLILYIFIYTLIGMQLYGGS 1811
Query: 885 YV 886
++
Sbjct: 1812 FL 1813
Score = 37.9 bits (84), Expect = 2.8
Identities = 17/61 (27%), Positives = 35/61 (57%)
Query: 223 NLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYM 282
+L LR FRVLR + + + +K ++ + + L +I+L + + ++ L+G+Q+Y
Sbjct: 1750 SLRILRVFRVLRVTRLLRSLKFMKILIKVISSILDKLFYIILLLILYIFIYTLIGMQLYG 1809
Query: 283 G 283
G
Sbjct: 1810 G 1810
>UniRef50_A0BKE9 Cluster: Chromosome undetermined scaffold_112, whole
genome shotgun sequence; n=4; cellular organisms|Rep:
Chromosome undetermined scaffold_112, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 2067
Score = 134 bits (324), Expect = 2e-29
Identities = 135/624 (21%), Positives = 272/624 (43%), Gaps = 47/624 (7%)
Query: 1227 MILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGF--QKYFTNAW 1284
++L+SS+ + + + + Y + I V F+E +I +A G K +
Sbjct: 1242 LVLISSIIVMIIRTYHDYEQEKSQYPYILLMILNVFMFLEDIICIIAKGLCMDKGSHINY 1301
Query: 1285 CWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAI 1344
W +I ++ L+ F I L RP++ M R++ + + AL Q++
Sbjct: 1302 SWQ--LIDLIYLLGFFIDSYKQNPI--VNICLFLGHFRPMKLMYRIKWLDKIRAALAQSL 1357
Query: 1345 PSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWEN 1404
+ +LL + W++F + G+ L+ ++ C D + ++ C W N
Sbjct: 1358 LDMLKILLTLISVWIMFGVFGIILYESQFGFCDD------KMQFYVNERECKESQREWIN 1411
Query: 1405 SPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSRE--VGRQPIRETNIYMYLYXXXXXX 1462
NFD++ A LF V+TF GW +IM A +SR+ G P T I Y Y
Sbjct: 1412 FKHNFDNITIALPTLFVVSTFDGWGEIMQVAENSRQSRYGPSPFA-TYISTYAYFISFCF 1470
Query: 1463 XXXXXTLNLFIGVIIDN--FNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPR 1520
L+ F G + FN+QK + + T+ Q+++ + P+ + P
Sbjct: 1471 VGSMFFLSFFTGTLFSKLRFNQQKIEMQDA-----TKFQREFTEIAPIILKDTPVFSTPP 1525
Query: 1521 PRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFS 1580
+ + F IV + F + L + ++++ Y + ++ + I+ ++
Sbjct: 1526 TKIVRRFASF-IVNNSIFQKFMFLMLLIDLICQLQYQYDMEVEYIRQINIIQRFIILFYA 1584
Query: 1581 SECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVL---SDIIEKYFVSPTLL---RVV 1633
L +L + YF W + +++ S+ L+ +D + YF S +++
Sbjct: 1585 LWIALLFMSLGINRYFDNNWRRYYTFLILISLCDLIADLENDWVIYYFQSNVFTPHYQMI 1644
Query: 1634 RVAKVGRVLRLV---KGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHV 1690
R+A + R LRL+ +G + L+ + +LP L + +L + M I+A+ G F +
Sbjct: 1645 RLAFMTRQLRLLVIFQGLTNLSRLIRVMGFALPFLAKLISILIITMIIYALIGCQLFGKI 1704
Query: 1691 KDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGS 1749
+ +DD NF F +++ LF+ ++ + ++ D + + C P+N P CGS
Sbjct: 1705 IEGAVIDDYINFTNFEYALLALFKCASGDDFRTIMTDTMHHNPSC--PEN----PDCCGS 1758
Query: 1750 ATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTD---DDYDMYYEIWQRF 1806
Y +++++ S +++N++I ++E + + + VQ + ++ D W ++
Sbjct: 1759 -DFNQLYFITFMLFSNYVLLNLFILGLIEQFEEFFQ-VQNSMIQTYVEEIDKIKTAWCKY 1816
Query: 1807 DPD-GSQYIRYDQLSDF-LDVLEP 1828
+ Q + Y L F LD+ +P
Sbjct: 1817 SAETNGQSMHYKFLCRFLLDIGQP 1840
Score = 43.6 bits (98), Expect = 0.056
Identities = 49/264 (18%), Positives = 118/264 (44%), Gaps = 30/264 (11%)
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKI 1587
I+ VT FD+II++ N + ++L S D ++ +F+++ E L++
Sbjct: 888 IIDNQVTQLFFDLIILI----NFIFLSLYGIADPIIISKCED-ISTVFLLV---EISLQM 939
Query: 1588 FALRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVK 1646
F +F N+ ++++ S + SD + ++ LR++R K R +K
Sbjct: 940 FTYPLQRFFSSKENVLQAIIMIASFIEFSFSDYLN---LTEQYLRLIRGTKCILFYRCLK 996
Query: 1647 GAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGG-LDDVYNFKTF 1705
+ + +++ + + +F+++ I+A+ GM + D+ L +++F
Sbjct: 997 YNQMAVLIGKIASITFKQYIYLTIFMFIIITIYAMIGMDLYASKFDQDDFLGQLHSFDNL 1056
Query: 1706 VQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISF 1765
+++++ +F + T+ W GV ++ G S ITY S ++I
Sbjct: 1057 MKAIMTIFNIMTNDDWYGVY--VL---------------GTGISTVAAITYSFSMVIILN 1099
Query: 1766 LIVINMYIAVILENYSQATEDVQE 1789
+ + +A++L+ + + ++ +E
Sbjct: 1100 YLTYGLVLAILLDGFGRYLDEKEE 1123
Score = 40.7 bits (91), Expect = 0.40
Identities = 28/103 (27%), Positives = 52/103 (50%), Gaps = 6/103 (5%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LR+ + + L+ LI +MG + L L +L I + I+A++G QLFGK ++
Sbjct: 1653 LRLLVIFQGLTNLSRLIRVMGFALPFLAKLISILIITMIIYALIGCQLFGK----IIEGA 1708
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVSC 935
D NFT+F ++ + +F+ G+ ++ + + SC
Sbjct: 1709 VIDDY--INFTNFEYALLALFKCASGDDFRTIMTDTMHHNPSC 1749
>UniRef50_A0DB70 Cluster: Chromosome undetermined scaffold_44, whole
genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_44, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 2133
Score = 131 bits (317), Expect = 2e-28
Identities = 126/608 (20%), Positives = 260/608 (42%), Gaps = 53/608 (8%)
Query: 1251 ILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQ 1310
IL + + IF +E++ K L + W ++ ++F+++
Sbjct: 1292 ILLIQNIVILAIFIVEIIAKGFILNEGTILRDFWKLVNMTYTTAYFLSFISSA------P 1345
Query: 1311 AFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
K L RPL ++ ++ V NA+V+++ I N++ V L +++F + + L+
Sbjct: 1346 ILKQAHHLIFCRPLMMVNMFGSVQGVKNAMVKSLIQIINIVAVILFVFMVFNVFAMHLYQ 1405
Query: 1371 GKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQ 1430
K C D+ + +S+ + C +N W N P NFD+ L +++ W +
Sbjct: 1406 KKMGYCEDLMNFHISY------SECQKQNKQWINHPYNFDNFVNGLFTLTMISSLDAWGE 1459
Query: 1431 IMNDAID--SREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAG 1488
IM + + G P + YL + GV+ F + KK
Sbjct: 1460 IMQVCYNASNSSTGPSPFK-IQWATYLLFVTFIFIGAMFFMGFLTGVLFTEFQKFTKKIE 1518
Query: 1489 GSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGL 1548
+T+DQ ++ + ++KP + P + + +++V K + + +
Sbjct: 1519 NK---NLTQDQSQFIQICSIVLNQKPGYS-HAPHSTIRKLAYKLVFSKYYKYLYNCILVT 1574
Query: 1549 NMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFVVV 1607
N + + S+ + + L + +IF+ +C++KI A Y W LF+ ++
Sbjct: 1575 NSIALCFLFDIHSQYTRNLANQLYQLHAIIFTFDCIIKIMAYGVTRYMSSRWRLFELIIT 1634
Query: 1608 MFSILSLVLSDIIEKYFVSPT----------LLRVVRVAKVGRVLRLVKGAKGIRTLLFA 1657
+ SI + D+ +++F T + +V + + ++L + + KG++ L+
Sbjct: 1635 VISIADF-MYDLKKRWFHLFTNGSQDQFIIYIAKVFLICRDIKILLIFQEFKGLQRLMRV 1693
Query: 1658 LAMSLPALFNICLLLFLVMFIFAIFGMSFF---MHVKDKGGLDDVY-NFKTFVQSMILLF 1713
L + L I + + +A+ G F +HV+ + +D+ Y NF+ F+ + ++LF
Sbjct: 1694 LFFTSSLLVKILYIQLTIQATYALVGTRLFDTYIHVQGR-AIDEYYLNFRNFINAALVLF 1752
Query: 1714 QMSTSAGWDG-VLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMY 1772
+ +T W ++D + C R CGS +Y LSY ++S ++V+N++
Sbjct: 1753 KCTTGDDWRALIIDCSRSNMYC------RDDVQQCGSGW-AYSYFLSYYLLSNIVVMNLF 1805
Query: 1773 IAVIL---ENYSQATEDVQEGLTDDDYDMYYEIWQR--FDPDG-SQYIRYDQLSDFLDVL 1826
+ ++ E++ T +V + ++ D + W R +D G + RY + FL L
Sbjct: 1806 VLALVDQFESFFSTTTNVIQTFV-ENIDHFCNCWCRYTYDTKGLKMHTRY--IGRFLLDL 1862
Query: 1827 EPPLQIHK 1834
PL K
Sbjct: 1863 NQPLGAQK 1870
Score = 58.0 bits (134), Expect = 2e-06
Identities = 74/302 (24%), Positives = 131/302 (43%), Gaps = 51/302 (16%)
Query: 123 ILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT-----TPTVESTEVIFTGIY 177
+L+ + I + I V+ LFIITT ++ I ++ + +F IY
Sbjct: 192 LLELLSQICEMIISSRVYRYVMLFIITTNIILLITKYYGNFYEQYQEFFDTQQEVFFIIY 251
Query: 178 TFESAVKVMARGFILQPFTYLRDAWNWLDFV-VIALAYVTMGIDLGNLAALRTFRVLRAL 236
E ++V + + WN D + V+ L VT G+ + + LR RVL L
Sbjct: 252 VLEICIRVSGHNIV----NFFCQFWNIFDLINVVILGLVTYGLISFDFSPLRAIRVLIFL 307
Query: 237 KTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPED 296
++ L+ A+I+S++ + + +++ + +FA +GL + KC V+ E+
Sbjct: 308 SQLS--SQLQLTFKALIQSLRYMLEALLIVLIFCVLFANIGLHQFATAFYNKC--VYLEE 363
Query: 297 GSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTS 356
G L+D+ +C W + Y C N F P+P T+
Sbjct: 364 GL--ILSDQ----YC----GWL-DCPIYSTCINVPII------------FAPDP---ITN 397
Query: 357 FDTFGWAFLSAFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLILAIVAM 405
F+ F +F+S R++T D W +L ++FV +IF+ F+ NLI+AI+
Sbjct: 398 FNNFINSFISIIRIITMDNWTDLMYPTLYTQSPLTWIYFVFVIFIVGFFAFNLIIAILKT 457
Query: 406 SY 407
Y
Sbjct: 458 YY 459
Score = 55.6 bits (128), Expect = 1e-05
Identities = 48/219 (21%), Positives = 102/219 (46%), Gaps = 19/219 (8%)
Query: 1224 VITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNA 1283
V+ I+ +++ L + + Q+ +F +I+ +E+ I+ +F
Sbjct: 212 VMLFIITTNIILLITKYYGNFYEQYQEFFDTQQEVFFIIYVLEICIRVSGHNIVNFFCQF 271
Query: 1284 WCWLDFI-IVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG-MRVVVNALV 1341
W D I +V++ L+ + G+ +F LRA+R L +S++ +++ AL+
Sbjct: 272 WNIFDLINVVILGLVTY--------GLISFD-FSPLRAIRVLIFLSQLSSQLQLTFKALI 322
Query: 1342 QAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYF-KCVDMNH-TTLSHEI-----IPDKNA 1394
Q++ + LL+ LIF ++FA +G+ FA ++ KCV + LS + P +
Sbjct: 323 QSLRYMLEALLIVLIFCVLFANIGLHQFATAFYNKCVYLEEGLILSDQYCGWLDCPIYST 382
Query: 1395 CTLENYTWENSPM-NFDHVGKAYLCLFQVATFKGWIQIM 1432
C + P+ NF++ +++ + ++ T W +M
Sbjct: 383 CINVPIIFAPDPITNFNNFINSFISIIRIITMDNWTDLM 421
Score = 52.8 bits (121), Expect = 9e-05
Identities = 60/289 (20%), Positives = 119/289 (41%), Gaps = 39/289 (13%)
Query: 1206 TLRLKTFKLIENTYFETAVITMILLSSLALA-LEDVHLPHRPILQDILYYMDRIFTVIFF 1264
T+R +KL+ + Y++ +++ +S+AL L D+H + L + LY ++ +IF
Sbjct: 1550 TIRKLAYKLVFSKYYKYLYNCILVTNSIALCFLFDIHSQYTRNLANQLY---QLHAIIFT 1606
Query: 1265 IEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAAL------CGAGG------IQAF 1312
+ +IK +A G +Y ++ W + II ++S+ +F+ L G I
Sbjct: 1607 FDCIIKIMAYGVTRYMSSRWRLFELIITVISIADFMYDLKKRWFHLFTNGSQDQFIIYIA 1666
Query: 1313 KTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGK 1372
K R ++ L +G++ ++ L + +L + L +A++G +LF
Sbjct: 1667 KVFLICRDIKILLIFQEFKGLQRLMRVLFFTSSLLVKILYIQLTIQATYALVGTRLF--- 1723
Query: 1373 YFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIM 1432
T H ++ + +NF + A L LF+ T W ++
Sbjct: 1724 ---------DTYIH----------VQGRAIDEYYLNFRNFINAALVLFKCTTGDDWRALI 1764
Query: 1433 NDAIDSREVGRQPIRETNI-YMYLYXXXXXXXXXXXTLNLFIGVIIDNF 1480
D S R +++ + Y Y +NLF+ ++D F
Sbjct: 1765 IDCSRSNMYCRDDVQQCGSGWAYSYFLSYYLLSNIVVMNLFVLALVDQF 1813
Score = 51.2 bits (117), Expect = 3e-04
Identities = 43/197 (21%), Positives = 97/197 (49%), Gaps = 20/197 (10%)
Query: 1600 NLFDFVVVMFSILSLVL-SDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFAL 1658
N+ D +V++ I+ +++ S I + + ++ +R + R++K + + ++
Sbjct: 958 NILDSMVIITQIIYIIIISTEIPQKDNYASEIKALRATNAILLYRIIKYNQFVTRIMRIA 1017
Query: 1659 AMSLPALFNICLLLFLVMFIFAIFGMSFFM-HVKDKGGLDDVYNFKTFVQSMILLFQMST 1717
++ ++ L+ ++ IF+I GM FF+ + ++ L +++FK+F +S + +F +ST
Sbjct: 1018 KITFKKYLSLMFLMLSIILIFSILGMQFFIENFQENESLSQLHSFKSFAKSWMTIFNIST 1077
Query: 1718 SAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGIT-YLLSYLVISFLIVINMYIAVI 1776
+ G+L +I ++ IGI Y ++ I++LI + +AV+
Sbjct: 1078 NDDAVGMLKVVIKFQQ----------------PWIGILFYFITVFTINYLI-YGLVMAVL 1120
Query: 1777 LENYSQATEDVQEGLTD 1793
L+ +S E V E D
Sbjct: 1121 LDAFSSELERVVEKQQD 1137
Score = 43.6 bits (98), Expect = 0.056
Identities = 37/158 (23%), Positives = 75/158 (47%), Gaps = 12/158 (7%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQS-ETFSAVLDYLNMIFIVIFSSECLLKIFAL 1590
I++ + + +++ I N++ + +Y E + D +F +I+ E +++
Sbjct: 203 IISSRVYRYVMLFIITTNIILLITKYYGNFYEQYQEFFDTQQEVFFIIYVLEICIRVSGH 262
Query: 1591 RY-HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
++F + WN+FD + V+ IL LV +I F SP LR +RV ++ L + +
Sbjct: 263 NIVNFFCQFWNIFDLINVV--ILGLVTYGLISFDF-SP--LRAIRV-----LIFLSQLSS 312
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
++ AL SL + L++ + +FA G+ F
Sbjct: 313 QLQLTFKALIQSLRYMLEALLIVLIFCVLFANIGLHQF 350
Score = 39.9 bits (89), Expect = 0.69
Identities = 21/99 (21%), Positives = 47/99 (47%)
Query: 183 VKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIV 242
V+++A+GFIL T LRD W ++ +++ L R L V +
Sbjct: 1306 VEIIAKGFILNEGTILRDFWKLVNMTYTTAYFLSFISSAPILKQAHHLIFCRPLMMVNMF 1365
Query: 243 PGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
++ + A+++S+ + +++ + +F VF + + +Y
Sbjct: 1366 GSVQGVKNAMVKSLIQIINIVAVILFVFMVFNVFAMHLY 1404
Score = 36.3 bits (80), Expect = 8.5
Identities = 23/91 (25%), Positives = 47/91 (51%), Gaps = 5/91 (5%)
Query: 825 KALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKN 884
KAL++ N + ++++ K + ++ I T +L F++ II IF+++GMQ F +N
Sbjct: 990 KALRATNAILLYRIIKYNQFVTRIMRIAKITFKKYLSLMFLMLSIILIFSILGMQFFIEN 1049
Query: 885 YVDYVDRFPDGDLPRWNFTDFMHSFMIVFRV 915
+ + + +F F S+M +F +
Sbjct: 1050 FQE-----NESLSQLHSFKSFAKSWMTIFNI 1075
>UniRef50_A5DB80 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 2224
Score = 129 bits (311), Expect = 9e-28
Identities = 128/642 (19%), Positives = 269/642 (41%), Gaps = 40/642 (6%)
Query: 1217 NTYFETAVITMILLSSLALALEDVHLP--HRPILQDI------LYYMDR----IFTVIFF 1264
N A++ + L +LAL + +L +R + + +Y+D IFT+ F
Sbjct: 1327 NKKVSEAIVFFMFLVTLALVIAACYLTPLYRKSVDQVHGKYNWTFYLDNGFLAIFTIEFL 1386
Query: 1265 IEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPL 1324
I++L L Y ++W +D +++ I F+A + G + F +R +ALR L
Sbjct: 1387 IKILADGLIFTPNAYVMSSWNIIDLWVLLALWIEFIAFMQNDGNLSRF--IRGFKALRAL 1444
Query: 1325 RAMSRMQ-GMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCV----DM 1379
R ++ + + ++ I N L+ L F+I G+ +F G+ C+ D
Sbjct: 1445 RLLTISEVAKNNFQHTMITGFWKIINAALISLCLLFPFSIWGLNVFNGRLGYCLDGSSDQ 1504
Query: 1380 NHTTLSHE-IIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDS 1438
+H ++ + + N + YT N + F+ ++ F++ + +GW ++ + + S
Sbjct: 1505 DHCLNEYDNEVFNWNIYSPNVYT--NPQLEFNRWATSFATFFEIVSLEGWTDLLINVMKS 1562
Query: 1439 REVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTED 1498
VG + L LF+ VII N++ +A +MT++
Sbjct: 1563 TGVGTPQEDFASPMNGFMIILFNFVSMVFILTLFVSVIISNYSRTTGRA------YMTKN 1616
Query: 1499 QKKYYNAMKKMGSKKPLKAIPRPRWRP-QAIVFEIVTDK--KFDMIIMLFIGLNMLTMTL 1555
Q +Y + + +P K + + + + +K + I+ + + + +
Sbjct: 1617 QISWYQIKRFLVQVRPSKRMSLAEMSTFRRFCYRMTVEKNVNWSRILTCVLTAQVAALLM 1676
Query: 1556 DHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVE-PWNLFDFVVVMFSILSL 1614
+ + S + + + ++K+ + FV WN F F V + + ++
Sbjct: 1677 ECFPSSTGLDKARTAVYIFASTFLLLQAIMKMIGQGWRTFVRYKWNTFSFFVSLGAFVTS 1736
Query: 1615 VLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFL 1674
++ I + + ++ V + ++ + + LL + SLP L ++ +
Sbjct: 1737 LIGLFIS---AESAFININKLFLVATLTFIIPRSDRLSQLLRFASASLPLLLSLSFTWIV 1793
Query: 1675 VMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVL-DGIINEEE 1733
V +FAI F + N ++ +++I+LF+ S GW+ ++ D I
Sbjct: 1794 VFLVFAIALNQIFGLTRIGPNGTGNLNLRSVPKALIVLFRCSFGEGWNYIMEDYTIEAPF 1853
Query: 1734 CDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQA-TEDVQEGLT 1792
C + S +CG+ +++ +IS I +NM++++IL+++S + L
Sbjct: 1854 CYSAHSLDDS--DCGNKQYAYILFIAWNLISMYIFLNMFVSLILDSFSYINSATAYSHLI 1911
Query: 1793 D-DDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIH 1833
D ++ + WQ+FDP+G+ YIR L L L + H
Sbjct: 1912 DREEVREFKRTWQKFDPEGTGYIRPYYLPKLLHSLNGAISFH 1953
Score = 64.9 bits (151), Expect = 2e-08
Identities = 78/400 (19%), Positives = 166/400 (41%), Gaps = 38/400 (9%)
Query: 1392 KNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNI 1451
KN+ + N +NFD++ ++ +F V + + IM +DS +G
Sbjct: 775 KNSKCISGDNPYNGTVNFDNILQSMELVFVVMSANTFTDIMYYTMDSDNLGA-------- 826
Query: 1452 YMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGS 1511
L+ +N+FI VI+ +FN + + ++ T + + G
Sbjct: 827 --CLFFIFCIFIMTVWLINIFIAVIVTSFNITRMEQQDQEKLSRTSTLL-FLKFFDRTGR 883
Query: 1512 KKPLKAIPRPRW-RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDY 1570
K + R RP I + KF+ + ++ I M T + + +L
Sbjct: 884 KNLARLDELKRLHRPLRIYY------KFEFVFVIVIIAAMFTQCFRKHGMDDYRRHLLYR 937
Query: 1571 LNMIFIVIFSSECLLKIFALRYH---YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSP 1627
++ VI +E +++ H +FV N FD + +F+ + +++ + +K
Sbjct: 938 FECVYTVILLAEIVIRFAMHLPHWRLFFVSNRNCFDLFLAVFTFI-IIIEPVKDKLGQGY 996
Query: 1628 TLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
L V ++ R R+V R L + ++ ALF++ L F++ F+ +I ++
Sbjct: 997 YWLTVFQLM---RFYRVVLATSFTRDLWMKIMVNFRALFDLTLFFFILTFVVSIIVSRYY 1053
Query: 1688 MHVKDKGGLDDV-YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGN 1746
+ D+ + T + + L+ ++++ W VL G+ +E + R
Sbjct: 1054 EGAIPVDDISDLDFPLHTLPNTFVGLYTITSTENWTDVLYGV---QEYATTTSYR----- 1105
Query: 1747 CGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATED 1786
+ G L+ + ++S +I++N++IA+I + + ED
Sbjct: 1106 ----SFGSVLLICWFIVSNMIILNIFIAIIAKTLEVSEED 1141
Score = 64.5 bits (150), Expect = 3e-08
Identities = 55/232 (23%), Positives = 106/232 (45%), Gaps = 26/232 (11%)
Query: 197 YLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIV------PGLKTIVG 250
YL+++W +DF+ + ++++ + + + A + RAL + IV G TI+
Sbjct: 627 YLKNSWQQVDFISMVTFWISLALSIDHYDAKHHIMLFRALSCLRIVRLCNMTTGTTTILT 686
Query: 251 AVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERF 310
A ++ L DV I +F ++G+Q + LT+ CV P++ + T N E++
Sbjct: 687 ACRAALPQLIDVSIFIACFWLLFGIIGVQSFKSSLTRHCVWTNPQNST---DTFINSEQY 743
Query: 311 CQNETNWYGEGGDYPL-CGNSSG---AGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLS 366
C + T+ G Y G S +C C+ G NP G +FD +
Sbjct: 744 CGSYTDLDGTARPYLFRDGTESSYVKGYRCPKNSKCIS--GDNPYNGTVNFDNILQSMEL 801
Query: 367 AFRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
F +M+ + + ++ LFF+ IF+ + +L+N+ +A++ S+
Sbjct: 802 VFVVMSANTFTDIMYYTMDSDNLGACLFFIFCIFIMTVWLINIFIAVIVTSF 853
Score = 52.8 bits (121), Expect = 9e-05
Identities = 31/118 (26%), Positives = 51/118 (43%), Gaps = 1/118 (0%)
Query: 1279 YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVN 1338
Y N+W +DFI ++ I+ ++ R L LR +R + G ++
Sbjct: 627 YLKNSWQQVDFISMVTFWISLALSIDHYDAKHHIMLFRALSCLRIVRLCNMTTGTTTILT 686
Query: 1339 ALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK-CVDMNHTTLSHEIIPDKNAC 1395
A A+P + +V + FWL+F I+GVQ F + CV N + I + C
Sbjct: 687 ACRAALPQLIDVSIFIACFWLLFGIIGVQSFKSSLTRHCVWTNPQNSTDTFINSEQYC 744
Score = 52.4 bits (120), Expect = 1e-04
Identities = 34/118 (28%), Positives = 63/118 (53%), Gaps = 5/118 (4%)
Query: 173 FTGIYTFESAVKVMARGFILQPFTYLRDAWNWLD-FVVIAL--AYVTMGIDLGNLAA-LR 228
F I+T E +K++A G I P Y+ +WN +D +V++AL ++ + GNL+ +R
Sbjct: 1377 FLAIFTIEFLIKILADGLIFTPNAYVMSSWNIIDLWVLLALWIEFIAFMQNDGNLSRFIR 1436
Query: 229 TFRVLRALKTVAIVPGLK-TIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVL 285
F+ LRAL+ + I K +I + + ++++ L F++ GL ++ G L
Sbjct: 1437 GFKALRALRLLTISEVAKNNFQHTMITGFWKIINAALISLCLLFPFSIWGLNVFNGRL 1494
Score = 40.7 bits (91), Expect = 0.40
Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 3/98 (3%)
Query: 1590 LRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
L+ Y W DF+ ++ +SL LS I+ Y ++ + R R++RL
Sbjct: 623 LKRAYLKNSWQQVDFISMVTFWISLALS--IDHYDAKHHIM-LFRALSCLRIVRLCNMTT 679
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
G T+L A +LP L ++ + + +F I G+ F
Sbjct: 680 GTTTILTACRAALPQLIDVSIFIACFWLLFGIIGVQSF 717
>UniRef50_UPI000065FCC5 Cluster: Voltage-dependent T-type calcium
channel subunit alpha-1I (Voltage- gated calcium channel
subunit alpha Cav3.3) (Ca(v)3.3).; n=1; Takifugu
rubripes|Rep: Voltage-dependent T-type calcium channel
subunit alpha-1I (Voltage- gated calcium channel subunit
alpha Cav3.3) (Ca(v)3.3). - Takifugu rubripes
Length = 1960
Score = 124 bits (298), Expect = 3e-26
Identities = 70/238 (29%), Positives = 129/238 (54%), Gaps = 13/238 (5%)
Query: 1562 ETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDI- 1619
++ VL Y N F F E +LK+ A + +F + WN D +V+ S++ + L +I
Sbjct: 1265 QSLDLVLKYCNYFFTSTFVLESILKLIAFGFRRFFKDRWNQLDLAIVLLSVMGITLEEIE 1324
Query: 1620 IEKYF-VSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFI 1678
I ++PT++R++RV ++ RVL+L+K A G+R LL + +LP + N+ LL L+ FI
Sbjct: 1325 ISAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFI 1384
Query: 1679 FAIFGMSFFMHVKDKG-----GLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEE 1733
+A G+ F + G+ F+ F + + LFQ+ST W+G++ + E
Sbjct: 1385 YAALGVELFGELVCNADYPCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTL--RE 1442
Query: 1734 CDLPDNERGSPGNCGSAT--IGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQE 1789
C PD+ NC + I Y +S+++ + ++IN+ +AV++++ + ++ QE
Sbjct: 1443 CP-PDHNTEVDYNCNPSLQFISPMYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQE 1499
Score = 109 bits (263), Expect = 6e-22
Identities = 58/150 (38%), Positives = 89/150 (59%), Gaps = 10/150 (6%)
Query: 1258 IFTVIFFIEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGI-QAF 1312
IFT IF EM +K +++G Q Y ++W LD +V VSL++ V ++ G I
Sbjct: 1108 IFTAIFVGEMTLKVVSMGLYMGEQAYLRSSWNVLDGFLVFVSLVDIVVSMAGGAKILGVL 1167
Query: 1313 KTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGK 1372
+ +R LR LRPLR +SR G+++VV L+ ++ I N++L+C F++IF I+GVQLF GK
Sbjct: 1168 RVLRLLRTLRPLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLFKGK 1227
Query: 1373 YFKCVDMNHTTLSHEIIPDKNACTLENYTW 1402
+F C+ + I +K+ C NY W
Sbjct: 1228 FFYCLGPDVKN-----ITNKSDCLQANYKW 1252
Score = 103 bits (248), Expect = 4e-20
Identities = 72/271 (26%), Positives = 140/271 (51%), Gaps = 34/271 (12%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR 1591
IV K F IM+ I +N ++M ++H+ Q + + VL+ N++F +F+ E +LK+ A
Sbjct: 484 IVESKYFSRGIMIAILINTISMGIEHHNQPDELTNVLEICNIVFTSMFTLEMILKLTAFG 543
Query: 1592 -YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
+ Y P+N+FD ++V+ S+ ++ + L V+R ++ RV++LV+
Sbjct: 544 FFEYLRNPYNIFDGIIVIISVCEIIGQ--------ADGGLSVLRTFRLLRVIKLVRFMPA 595
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF---MHVKDKGG--LDDVYNFKTF 1705
+R L L ++ + C+LL L +FIF+I GM F +K + G + D NF +
Sbjct: 596 LRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLKTEAGDTVPDRKNFDSL 655
Query: 1706 VQSMILLFQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVIS 1764
+ +++ +FQ+ T W+ VL +G+++ C A++ Y ++ +
Sbjct: 656 LWAIVTVFQILTQEDWNVVLYNGMVSTSPC---------------ASL---YFVALMTFG 697
Query: 1765 FLIVINMYIAVILENYSQATEDVQEGLTDDD 1795
++ N+ +A+++E + QA D +DDD
Sbjct: 698 NYVLFNLLVAILVEGF-QAEGDANRSYSDDD 727
Score = 89.0 bits (211), Expect = 1e-15
Identities = 58/235 (24%), Positives = 122/235 (51%), Gaps = 27/235 (11%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W +R K + ++E+ YF ++ IL++++++ +E + P L ++L + +FT +F
Sbjct: 474 WNGMRRKLWGIVESKYFSRGIMIAILINTISMGIEHHNQPDE--LTNVLEICNIVFTSMF 531
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRP 1323
+EM++K A GF +Y N + D IIV++S+ + GG+ +T R LR ++
Sbjct: 532 TLEMILKLTAFGFFEYLRNPYNIFDGIIVIISVCEIIGQ--ADGGLSVLRTFRLLRVIKL 589
Query: 1324 LRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTT 1383
+R M ++ VV L++ + ++ ++ ++F IF+I+G+ +F K+ + T
Sbjct: 590 VRFMPALRRQLVV---LMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKF------SLKT 640
Query: 1384 LSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDS 1438
+ + +PD+ NFD + A + +FQ+ T + W ++ + + S
Sbjct: 641 EAGDTVPDRK--------------NFDSLLWAIVTVFQILTQEDWNVVLYNGMVS 681
Score = 84.6 bits (200), Expect = 2e-14
Identities = 67/254 (26%), Positives = 116/254 (45%), Gaps = 31/254 (12%)
Query: 1251 ILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAA---LCGAG 1307
+L Y + FT F +E ++K +A GF+++F + W LD IV++S++ + A
Sbjct: 1270 VLKYCNYFFTSTFVLESILKLIAFGFRRFFKDRWNQLDLAIVLLSVMGITLEEIEISAAL 1329
Query: 1308 GIQA--FKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMG 1365
I + MR LR R L+ + GMR +++ +VQA+P + N+ L+ ++ + I+A +G
Sbjct: 1330 PINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALG 1389
Query: 1366 VQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATF 1425
V+LF G+ D +S T EN+ G A+L LFQV+T
Sbjct: 1390 VELF-GELVCNADYPCEGMSRH-------ATFENF------------GMAFLTLFQVSTG 1429
Query: 1426 KGWIQIMNDAI------DSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDN 1479
W IM D + + EV +Y +N+ + V++ +
Sbjct: 1430 DNWNGIMKDTLRECPPDHNTEVDYNCNPSLQFISPMYFVSFVLTAQFVLINVVVAVLMKH 1489
Query: 1480 FNEQKKKAGGSLEM 1493
++ K+A EM
Sbjct: 1490 LDDSNKEAQEEAEM 1503
Score = 77.8 bits (183), Expect = 3e-12
Identities = 49/168 (29%), Positives = 92/168 (54%), Gaps = 12/168 (7%)
Query: 122 WILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMP-------TTPTVESTEVIFT 174
++ D +N +RR I+ FS I+ IL+N I M + T +E ++FT
Sbjct: 469 YLRDIWNGMRRKLWGIVESKYFSRGIMIAILINTISMGIEHHNQPDELTNVLEICNIVFT 528
Query: 175 GIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM-GIDLGNLAALRTFRVL 233
++T E +K+ A GF F YLR+ +N D +++ ++ + G G L+ LRTFR+L
Sbjct: 529 SMFTLEMILKLTAFGF----FEYLRNPYNIFDGIIVIISVCEIIGQADGGLSVLRTFRLL 584
Query: 234 RALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
R +K V +P L+ + +++++ N+ +L M + +F+++G+ I+
Sbjct: 585 RVIKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIF 632
Score = 72.5 bits (170), Expect = 1e-10
Identities = 37/119 (31%), Positives = 67/119 (56%), Gaps = 7/119 (5%)
Query: 172 IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID-------LGNL 224
IFT I+ E +KV++ G + YLR +WN LD ++ ++ V + + LG L
Sbjct: 1108 IFTAIFVGEMTLKVVSMGLYMGEQAYLRSSWNVLDGFLVFVSLVDIVVSMAGGAKILGVL 1167
Query: 225 AALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
LR R LR L+ ++ PGLK +V +I S+K + +++++ +F ++G+Q++ G
Sbjct: 1168 RVLRLLRTLRPLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLFKG 1226
Score = 52.8 bits (121), Expect = 9e-05
Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 9/119 (7%)
Query: 1217 NTYFETAVITMILLSSLALALEDV--HLPHRPILQDILYYMDRIFTVIFFIEMLIKWLAL 1274
+T+FE I +ILL+ + L + ++ IL D + F +EM++K +AL
Sbjct: 4 STWFERITIMVILLNCVTLGMYQPCENIDCASDHCQILQAFDAFIYIFFALEMVVKMVAL 63
Query: 1275 GF---QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRM 1330
G + Y + W LDF IVM ++ + L +RT+R LRPL+A++R+
Sbjct: 64 GIFGRRCYLGDTWNRLDFFIVMAGMVEYSLDLQNIN----LSAIRTVRVLRPLKAINRV 118
Score = 51.6 bits (118), Expect = 2e-04
Identities = 30/69 (43%), Positives = 39/69 (56%), Gaps = 3/69 (4%)
Query: 177 YTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLG--NLAALRTFRVLR 234
+ E VK++A G I YL D WN LDF ++ V +DL NL+A+RT RVLR
Sbjct: 52 FALEMVVKMVALG-IFGRRCYLGDTWNRLDFFIVMAGMVEYSLDLQNINLSAIRTVRVLR 110
Query: 235 ALKTVAIVP 243
LK + VP
Sbjct: 111 PLKAINRVP 119
Score = 51.6 bits (118), Expect = 2e-04
Identities = 33/119 (27%), Positives = 60/119 (50%), Gaps = 8/119 (6%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNY- 885
L++ LRV KL + P L + ++ +TM + +L + IFIF+++GM +FG +
Sbjct: 578 LRTFRLLRVIKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFS 637
Query: 886 --VDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSCIPFFLA 941
+ D PD R NF + + + VF++L E W +++ M+ +F+A
Sbjct: 638 LKTEAGDTVPD----RKNFDSLLWAIVTVFQILTQEDWNVVLYNGMVSTSPCASLYFVA 692
Score = 48.8 bits (111), Expect = 0.001
Identities = 37/124 (29%), Positives = 61/124 (49%), Gaps = 13/124 (10%)
Query: 1572 NMIFIVIFSSECLLKIFALRYH-----YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVS 1626
N IF IF E LK+ ++ + Y WN+ D +V S++ +V+S +
Sbjct: 1106 NYIFTAIFVGEMTLKVVSMGLYMGEQAYLRSSWNVLDGFLVFVSLVDIVVSMAGGAKILG 1165
Query: 1627 PTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNI---CLLLFLVMFIFAIFG 1683
+LRV+R+ + R LR++ A G++ ++ L SL + NI C F+ IF I G
Sbjct: 1166 --VLRVLRLLRTLRPLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFI---IFGILG 1220
Query: 1684 MSFF 1687
+ F
Sbjct: 1221 VQLF 1224
Score = 44.0 bits (99), Expect = 0.042
Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 2/96 (2%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
RV KL K + L+ + + + +GNL + ++ FI+A +G++LFG+ V D
Sbjct: 1346 RVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGE-LVCNADYPC 1404
Query: 894 DGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
+G F +F +F+ +F+V G+ W M D +
Sbjct: 1405 EGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTL 1440
Score = 43.6 bits (98), Expect = 0.056
Identities = 21/70 (30%), Positives = 42/70 (60%), Gaps = 11/70 (15%)
Query: 349 NPNYGYTSFDTFGWAFLSAFRLMTQDYW-ENLYQ----------LFFVVIIFLGSFYLVN 397
NP+ G SFD +A++ F+++T + W E +Y ++F+++I +GSF+++N
Sbjct: 261 NPHKGAISFDNIVYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFILLIIIGSFFMIN 320
Query: 398 LILAIVAMSY 407
L L ++A +
Sbjct: 321 LCLVVIATQF 330
Score = 39.5 bits (88), Expect = 0.91
Identities = 21/80 (26%), Positives = 41/80 (51%), Gaps = 10/80 (12%)
Query: 1407 MNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXX 1466
++FD++ A++ +FQV T +GW++IM +D+ + Y ++Y
Sbjct: 267 ISFDNIVYAWIVIFQVITLEGWVEIMYYVMDAH----------SFYNFIYFILLIIIGSF 316
Query: 1467 XTLNLFIGVIIDNFNEQKKK 1486
+NL + VI F+E K++
Sbjct: 317 FMINLCLVVIATQFSETKQR 336
Score = 36.7 bits (81), Expect = 6.4
Identities = 14/49 (28%), Positives = 27/49 (55%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
LR ++ P L L++ + ++ +GN+ + C IF ++G+QLF
Sbjct: 1176 LRPLRVISRAPGLKLVVETLITSLKPIGNIVLICCAFFIIFGILGVQLF 1224
>UniRef50_A7SZ40 Cluster: Predicted protein; n=2; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 132
Score = 124 bits (298), Expect = 3e-26
Identities = 52/113 (46%), Positives = 79/113 (69%), Gaps = 2/113 (1%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LRV LA+SW T+ LI + ++ + N+T +L +II++FAV+GM++FG +Y + F
Sbjct: 1 LRVLYLAQSWETMAKLIRAIAHSVDPIFNITCILGVIIYVFAVVGMRVFGPHYT--AEAF 58
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCMLVGDVSCIPFFLATVVI 945
+PRWNFTDF HSFM+VFR+LC EW+E +WDCM V + + + FFL +++
Sbjct: 59 GSRGIPRWNFTDFTHSFMMVFRILCSEWVEPLWDCMRVTNTAALLFFLPALIV 111
Score = 41.1 bits (92), Expect = 0.30
Identities = 24/83 (28%), Positives = 47/83 (56%), Gaps = 4/83 (4%)
Query: 1640 RVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF--MHVKDKGGLD 1697
RVL L + + + L+ A+A S+ +FNI +L +++++FA+ GM F + + G
Sbjct: 2 RVLYLAQSWETMAKLIRAIAHSVDPIFNITCILGVIIYVFAVVGMRVFGPHYTAEAFGSR 61
Query: 1698 DV--YNFKTFVQSMILLFQMSTS 1718
+ +NF F S +++F++ S
Sbjct: 62 GIPRWNFTDFTHSFMMVFRILCS 84
>UniRef50_A2AFU9 Cluster: Calcium channel voltage-dependent alpha 1F
subunit; n=19; Euteleostomi|Rep: Calcium channel
voltage-dependent alpha 1F subunit - Mus musculus (Mouse)
Length = 247
Score = 116 bits (279), Expect = 7e-24
Identities = 67/224 (29%), Positives = 127/224 (56%), Gaps = 14/224 (6%)
Query: 1634 RVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF--MHVK 1691
R+ +V R+++L+ +GIRTLL+ S AL + LL+ ++ FI+A+ GM F + ++
Sbjct: 15 RLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIAMIFFIYAVIGMQMFGKVALQ 74
Query: 1692 DKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPG---NCG 1748
D ++ NF+TF Q+++LLF+ +T W ++ + CD P+++ G PG CG
Sbjct: 75 DGTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLASLPGNRCD-PESDFG-PGEEFTCG 132
Query: 1749 SATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDP 1808
S + I Y +S+ ++ ++IN+++AVI++N+ T D L D + IW +DP
Sbjct: 133 S-SFAIVYFISFFMLCAFLIINLFVAVIMDNFDYLTRD-WSILGPHHLDEFKRIWSEYDP 190
Query: 1809 DGSQYIRYDQLSDFLDVLEPPLQIHK--PNKY---KIISMDIPI 1847
I++ + L ++PPL K P++ ++++M++P+
Sbjct: 191 GAKGRIKHLDVVALLRRIQPPLGFGKLCPHRVACKRLVAMNVPL 234
Score = 41.5 bits (93), Expect = 0.23
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 5/93 (5%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
+R+ KL + L+ ++ AL + ++ +I FI+AV+GMQ+FGK + +
Sbjct: 20 MRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIAMIFFIYAVIGMQMFGKVALQDGTQI 79
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESM 924
+ NF F + +++FR GE W E M
Sbjct: 80 NRNN----NFQTFPQAVLLLFRCATGEAWQEIM 108
>UniRef50_A7TIK0 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 995
Score = 115 bits (277), Expect = 1e-23
Identities = 120/598 (20%), Positives = 247/598 (41%), Gaps = 33/598 (5%)
Query: 1254 YMDRIFTVIFFIEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAAL-CGAGG 1308
Y D T F +E +IK +A GF Y N W +DFI++ I+ +++
Sbjct: 266 YFDIGVTSFFTLEFIIKTVADGFIYTPNAYLRNPWNVIDFIVMEYMWIDVYSSIRSDNSN 325
Query: 1309 IQAFKTMRTLRALRPLRAMSRMQGMR--VVVNALVQAIPSIFNVLLVCLIFWLIFAIMGV 1366
+ F+ +R R + + + ++ N L + + F C+IF F + G+
Sbjct: 326 AKIFRAFTAIRIFRLITISDKGKDTFHILIFNGLSKLPMTAFASF--CIIF--PFTVWGL 381
Query: 1367 QLFAGKYFKCVD--MNHTTLSHEIIPDKNACTLENYTWENSP-MNFDHVGKAYLCLFQVA 1423
LF G C D + ++E ++ + P + FD+ G + L+++
Sbjct: 382 HLFRGHLGVCNDNSFGYDGCTNEFSNTVFKWSIMSPRVYKEPYLYFDNFGVSLKSLYEII 441
Query: 1424 TFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQ 1483
+ +GW+ ++ ++S VG+ PI + + LNLF+ II + +
Sbjct: 442 SLEGWVDLLMALVNSTGVGKIPIVNASPGNAFFIILFNFISMGFILNLFVSTIIASHSTN 501
Query: 1484 KKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRP-QAIVFEIV--TDKKFDM 1540
A F T+D+K + K + P + ++ + ++F V +++ +++
Sbjct: 502 TGLA------FQTKDEKVWIYTKKLLSQAYPERVPDTNNYKNFRLMIFNFVNGSNQYYNV 555
Query: 1541 IIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPW 1599
+ + + ++ + ++ V L M S LL ++ + YF W
Sbjct: 556 SVNVILYFHISLLLSQFNNNAQEVWIVRRKLYMATTTALLSSALLSLYGNGFRIYFKNKW 615
Query: 1600 NLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALA 1659
F F ++ + L +S +S L +V + L ++ + L
Sbjct: 616 MYFKFYILWSAFLFTFISSSYADDNISSNL--AAKVFRSSIFLFIIPQFDVLSQLSDIAI 673
Query: 1660 MSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSA 1719
S P L + +V +FAI F K + NF+T +++++LF+ S
Sbjct: 674 ASGPYLLPLAYTWLIVFLVFAITLNQLFGLTKLGPNTTENLNFRTVPKALLVLFRCSFGE 733
Query: 1720 GWDGVLDGI-INEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILE 1778
W+ +L+ I ++ EC GNC S+ ++ + +IS I +N++ ++I+
Sbjct: 734 RWNYILEDIALSYPEC----TPNSILGNCESSVFAYIIIILWNIISMYIFMNIFASIIIT 789
Query: 1779 NYSQ--ATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPPLQIHK 1834
++ + + + + + W++FD G YI++ +++ FL+ E PL K
Sbjct: 790 HFGNVYGESNSSDRIKKRHIRNFTKAWKKFDFYGVGYIQFGEITPFLNSFEGPLSFKK 847
Score = 52.0 bits (119), Expect = 2e-04
Identities = 32/117 (27%), Positives = 51/117 (43%), Gaps = 5/117 (4%)
Query: 174 TGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIAL----AYVTMGIDLGNLAALRT 229
T +T E +K +A GFI P YLR+ WN +DF+V+ Y ++ D N R
Sbjct: 272 TSFFTLEFIIKTVADGFIYTPNAYLRNPWNVIDFIVMEYMWIDVYSSIRSDNSNAKIFRA 331
Query: 230 FRVLRALKTVAIV-PGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVL 285
F +R + + I G T + + L + + F + GL ++ G L
Sbjct: 332 FTAIRIFRLITISDKGKDTFHILIFNGLSKLPMTAFASFCIIFPFTVWGLHLFRGHL 388
>UniRef50_UPI00015A4429 Cluster: UPI00015A4429 related cluster; n=1;
Danio rerio|Rep: UPI00015A4429 UniRef100 entry - Danio
rerio
Length = 1023
Score = 109 bits (261), Expect = 1e-21
Identities = 78/286 (27%), Positives = 146/286 (51%), Gaps = 34/286 (11%)
Query: 1520 RPRWRPQAI-VFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETF-SAVLDYLNMIFIV 1577
R W + ++ IV K F+ IM+ I +N ++M ++H+QQ++ F + VL+ N++F
Sbjct: 462 RELWMQTRVKLWGIVESKYFNRGIMVAILINTISMGIEHHQQTQRFLNIVLEISNIVFTS 521
Query: 1578 IFSSECLLKIFALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVA 1636
+F+ E +LK+ A ++Y P+N+FD V+V+ S+ +V S L ++R
Sbjct: 522 MFALEMILKLTAFGCFNYLRNPYNIFDGVIVIISVCEIVSQ--------SDGGLSILRTF 573
Query: 1637 KVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF---MHVKDK 1693
++ RVL+LV+ +R L L ++ + C+LL L +FIF+I GM F +K+
Sbjct: 574 RLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLKND 633
Query: 1694 GG--LDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSAT 1751
G + D NF + + +++ +FQ+ T W+ VL G ++
Sbjct: 634 SGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYN-----------------GMASTSP 676
Query: 1752 IGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYD 1797
+ Y ++ + ++ N+ +A+++E + QA D +DDD D
Sbjct: 677 LAALYFVALMTFGNYVLFNLLVAILVEGF-QAEGDANRSYSDDDDD 721
Score = 92.3 bits (219), Expect = 1e-16
Identities = 58/175 (33%), Positives = 95/175 (54%), Gaps = 14/175 (8%)
Query: 1219 YFETAVITMILLSSLALAL----EDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLAL 1274
+FE + +ILL+ + L + E+++ +L D + F +EM++K LAL
Sbjct: 1 WFERVSMLVILLNCVTLGMYQPCENINCSSERC--QVLQAFDAFIYIFFALEMVVKMLAL 58
Query: 1275 GF---QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQ 1331
G + Y + W LDF IVM ++ + + +RT+R LRPL+A++R+
Sbjct: 59 GIFGHRCYLGDTWNRLDFFIVMAGVVEYSLDVQDIN----LTAIRTVRVLRPLKAINRVP 114
Query: 1332 GMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FKCVDMNHTTLS 1385
MR++VN L+ +P + NVLL+C + IF I+GVQL+AG +C + TLS
Sbjct: 115 SMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCYPEENFTLS 169
Score = 86.2 bits (204), Expect = 8e-15
Identities = 65/280 (23%), Positives = 132/280 (47%), Gaps = 36/280 (12%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W R+K + ++E+ YF ++ IL++++++ +E H + L +L + +FT +F
Sbjct: 465 WMQTRVKLWGIVESKYFNRGIMVAILINTISMGIEH-HQQTQRFLNIVLEISNIVFTSMF 523
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRP 1323
+EM++K A G Y N + D +IV++S+ V+ GG+ +T R LR L+
Sbjct: 524 ALEMILKLTAFGCFNYLRNPYNIFDGVIVIISVCEIVSQ--SDGGLSILRTFRLLRVLKL 581
Query: 1324 LRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTT 1383
+R M ++ VV L++ + ++ ++ ++F IF+I+G+ +F K+ D
Sbjct: 582 VRFMPALRRQLVV---LMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLKND----- 633
Query: 1384 LSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGR 1443
S + +PD+ NFD + A + +FQ+ T + W ++ + + S
Sbjct: 634 -SGDTVPDRK--------------NFDSLLWAIVTVFQILTQEDWNVVLYNGMAS----- 673
Query: 1444 QPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQ 1483
T+ LY NL + ++++ F +
Sbjct: 674 -----TSPLAALYFVALMTFGNYVLFNLLVAILVEGFQAE 708
Score = 81.8 bits (193), Expect = 2e-13
Identities = 42/122 (34%), Positives = 72/122 (59%), Gaps = 6/122 (4%)
Query: 177 YTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLG--NLAALRTFRVLR 234
+ E VK++A G I YL D WN LDF ++ V +D+ NL A+RT RVLR
Sbjct: 47 FALEMVVKMLALG-IFGHRCYLGDTWNRLDFFIVMAGVVEYSLDVQDINLTAIRTVRVLR 105
Query: 235 ALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFP 294
LK + VP ++ +V +++++ L +V++L F +F ++G+Q++ G+L +C +P
Sbjct: 106 PLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRC---YP 162
Query: 295 ED 296
E+
Sbjct: 163 EE 164
Score = 66.1 bits (154), Expect = 9e-09
Identities = 36/118 (30%), Positives = 69/118 (58%), Gaps = 7/118 (5%)
Query: 166 VESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLD--FVVIALAYVTMGIDLGN 223
+E + ++FT ++ E +K+ A G F YLR+ +N D V+I++ + D G
Sbjct: 512 LEISNIVFTSMFALEMILKLTAFGC----FNYLRNPYNIFDGVIVIISVCEIVSQSD-GG 566
Query: 224 LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
L+ LRTFR+LR LK V +P L+ + +++++ N+ +L M + +F+++G+ I+
Sbjct: 567 LSILRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIF 624
Score = 61.7 bits (143), Expect = 2e-07
Identities = 49/160 (30%), Positives = 78/160 (48%), Gaps = 19/160 (11%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSA------VLDYLNMIFIVIFSSECLLKIFALR 1591
F+ + ML I LN +T+ + YQ E + VL + + F+ E ++K+ AL
Sbjct: 2 FERVSMLVILLNCVTLGM--YQPCENINCSSERCQVLQAFDAFIYIFFALEMVVKMLALG 59
Query: 1592 YH----YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKG 1647
Y + WN DF +VM ++ L D+ + ++ T +R VRV R L+ +
Sbjct: 60 IFGHRCYLGDTWNRLDFFIVMAGVVEYSL-DVQD---INLTAIRTVRVL---RPLKAINR 112
Query: 1648 AKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+R L+ L +LP L N+ LL F V FIF I G+ +
Sbjct: 113 VPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLW 152
Score = 51.6 bits (118), Expect = 2e-04
Identities = 34/119 (28%), Positives = 59/119 (49%), Gaps = 8/119 (6%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L++ LRV KL + P L + ++ +TM + +L + IFIF+++GM +FG +
Sbjct: 570 LRTFRLLRVLKLVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFS 629
Query: 887 ---DYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSCIPFFLA 941
D D PD R NF + + + VF++L E W +++ M +F+A
Sbjct: 630 LKNDSGDTVPD----RKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSPLAALYFVA 684
Score = 39.1 bits (87), Expect = 1.2
Identities = 16/56 (28%), Positives = 34/56 (60%)
Query: 826 ALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
A+++ LR K P++ +L++++ T+ LGN+ + + FIF ++G+QL+
Sbjct: 97 AIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFFVFFIFGIIGVQLW 152
>UniRef50_A7E792 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Sclerotinia sclerotiorum 1980
Length = 2034
Score = 104 bits (250), Expect = 2e-20
Identities = 101/473 (21%), Positives = 205/473 (43%), Gaps = 33/473 (6%)
Query: 1217 NTYFETAVITMILLSSLALALED----VHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
+ + ++ M+LL+ + L + P + ++ + D IF +IF +E LIK +
Sbjct: 1235 SAFLYICIVAMVLLACITTPLYQREYFIANPDKSTAKNWFVFCDFIFGLIFTVEALIKVI 1294
Query: 1273 ALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMS 1328
A GF Y+ + W ++D ++++ IN + +L G I + + +ALR LR ++
Sbjct: 1295 ADGFFWTPNAYYRSTWGFIDGLVLVTLWINVITSLMDDGAIA--RAVGAFKALRALRLLN 1352
Query: 1329 RMQGMRVVVNALVQAIP-SIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLS-- 1385
R ++++ + + V + + FAI GV LF G+ C D + L+
Sbjct: 1353 VSDSARNTFHSVILVGGLKVLSAAFVSMSLLIPFAIYGVNLFNGQLETCNDGDIANLTDC 1412
Query: 1386 ---HEIIPDKNACTLENYTWENSPM-NFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREV 1441
+ P + + +P +FD+ G + LFQ+ + +GW+ +M + +
Sbjct: 1413 FGEYYSQPFSGDWNVVSPRQVGNPWYDFDNFGASLFILFQIVSQEGWVDVMFETMSITGR 1472
Query: 1442 GRQPIRETNI-YMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQK 1500
G P T+ + ++ L LFI V + N+ EQ A F+T DQ+
Sbjct: 1473 GLNPGDPTSAEFNAVFFVIFNLLATVFILTLFISVFMRNYTEQTGIA------FLTSDQR 1526
Query: 1501 KYYNAMKKM----GSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLD 1556
+ K + SK+P P WR K+ + L + +++ + ++
Sbjct: 1527 SWVELRKLLRQVSPSKRPSSKDPH-WWRDWCYKRATRKHGKWHSAMTLTLVFHLILLLVE 1585
Query: 1557 HYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYF-VEPWNLFDFVVVMFSILSLV 1615
Y + + + DY+ + + ++ +++I L + F W++F V ++++ +
Sbjct: 1586 FYPEPKIWDTTRDYIFLACTIFYTLNVIVRIIGLTWPRFRRSSWDVFSIFAVFGTLVTTL 1645
Query: 1616 LSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNI 1668
L + F S +++ ++ V VL L+ + L A SL A+ N+
Sbjct: 1646 L---LLTNFNSQVYVQLHKLFLVAIVLLLIPRNDALDQLFKTAAASLTAIGNL 1695
Score = 68.1 bits (159), Expect = 2e-09
Identities = 44/155 (28%), Positives = 81/155 (52%), Gaps = 15/155 (9%)
Query: 1635 VAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF---MHVK 1691
V ++ R+ R+V G + R+L+ + + + N+ L +FL+ F+ AIF + F + +
Sbjct: 898 VFQILRIYRVVMGVEITRSLIMLVLGNASGIGNLVLFVFLITFLVAIFAVQLFRGDIPAQ 957
Query: 1692 DKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSAT 1751
D GG F T S + L+Q+ +S W +L + +N R N G
Sbjct: 958 DDGGDTITVTFATIFNSFLGLYQILSSENWTDILYNVTGI------NNSR----NTG--W 1005
Query: 1752 IGITYLLSYLVISFLIVINMYIAVILENYSQATED 1786
IG T+L+ + +++ I++NM+IAVI EN+ + ++
Sbjct: 1006 IGATFLIGWFILANFILVNMFIAVIQENFDVSEDE 1040
Score = 64.5 bits (150), Expect = 3e-08
Identities = 70/279 (25%), Positives = 126/279 (45%), Gaps = 35/279 (12%)
Query: 162 TTPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIA---LAYVTMG 218
TT T F + S V+ A+ L +LR ++N LDF+ + +A+V
Sbjct: 489 TTNTQRPIVNTFAQMQAMTSTVE-QAQRLQLARRAFLRHSFNRLDFLAVVSYWIAFVLSI 547
Query: 219 IDLGNLAALRTFRVL---RALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFAL 275
+ + + L FR+L R L+ +A+ G I+ ++ ++ L +V L F +FA+
Sbjct: 548 LGVEHTYHLYVFRMLSCLRILRLLALTSGTAIILRSLKKATPLLLNVSFLIGFFWLLFAI 607
Query: 276 MGLQIYMGVLTQKCVKVFPED-GSWGNLTDENWERFCQNETN--------WYGEGGDYPL 326
+G+Q + G L ++CV + P+D + N N ++C + N W PL
Sbjct: 608 IGIQSFKGSLDRQCVWIDPDDIQNTNNTAFINSLQYCGGQFNKDNSSHDPWMVSNSSNPL 667
Query: 327 CGNSSGAGQCEPGYVCLQG-----FGPN--PNYGYTSFDTFGWAFLSAFRLMTQDYWENL 379
+ G G + GY+C +G P+ P G +FD G + F +MT + + +L
Sbjct: 668 YPLNPGTGSSK-GYLCPEGSYCIQLPPDLLPFNGTATFDNIGQSLELVFVIMTGNTFTDL 726
Query: 380 Y-----------QLFFVVIIFLGSFYLVNLILAIVAMSY 407
+FF I + +L+NL++A++ S+
Sbjct: 727 MYYTTDSDYLAAAIFFAGGIVIMMLWLMNLLIAVITSSF 765
Score = 60.1 bits (139), Expect = 6e-07
Identities = 32/100 (32%), Positives = 53/100 (53%)
Query: 1272 LALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQ 1331
L L + + +++ LDF+ V+ I FV ++ G R L LR LR ++
Sbjct: 516 LQLARRAFLRHSFNRLDFLAVVSYWIAFVLSILGVEHTYHLYVFRMLSCLRILRLLALTS 575
Query: 1332 GMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
G +++ +L +A P + NV + FWL+FAI+G+Q F G
Sbjct: 576 GTAIILRSLKKATPLLLNVSFLIGFFWLLFAIIGIQSFKG 615
Score = 59.7 bits (138), Expect = 8e-07
Identities = 67/252 (26%), Positives = 111/252 (44%), Gaps = 40/252 (15%)
Query: 135 IYILVHPLFSLFIITTILVNCILMIM-PTTPTVES----TEVIFTGIYTFESAVKVMARG 189
+YI + + L ITT L I P T ++ + IF I+T E+ +KV+A G
Sbjct: 1238 LYICIVAMVLLACITTPLYQREYFIANPDKSTAKNWFVFCDFIFGLIFTVEALIKVIADG 1297
Query: 190 FILQPFTYLRDAWNWLDFVVIALAY---VTMGIDLGNLA-ALRTFRVLRALKTVAIVPGL 245
F P Y R W ++D +V+ + +T +D G +A A+ F+ LRAL+ + +
Sbjct: 1298 FFWTPNAYYRSTWGFIDGLVLVTLWINVITSLMDDGAIARAVGAFKALRALRLLNVSDSA 1357
Query: 246 K-TIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTD 304
+ T ++ + ++M L FA+ G+ ++ G L + C DG NLTD
Sbjct: 1358 RNTFHSVILVGGLKVLSAAFVSMSLLIPFAIYGVNLFNGQL-ETC-----NDGDIANLTD 1411
Query: 305 ENWERFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAF 364
C +GE P G+ + + G NP Y FD FG +
Sbjct: 1412 ------C------FGEYYSQPFSGDWNVVSPRQVG---------NPWY---DFDNFGASL 1447
Query: 365 LSAFRLMTQDYW 376
F++++Q+ W
Sbjct: 1448 FILFQIVSQEGW 1459
Score = 39.1 bits (87), Expect = 1.2
Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 8/99 (8%)
Query: 1599 WNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFAL 1658
+N DF+ V+ ++ VLS + ++ L V R+ R+LRL+ G +L +L
Sbjct: 528 FNRLDFLAVVSYWIAFVLSILGVEHTYH---LYVFRMLSCLRILRLLALTSGTAIILRSL 584
Query: 1659 AMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLD 1697
+ P L N+ L+ +FAI G+ F KG LD
Sbjct: 585 KKATPLLLNVSFLIGFFWLLFAIIGIQSF-----KGSLD 618
Score = 39.1 bits (87), Expect = 1.2
Identities = 20/85 (23%), Positives = 45/85 (52%), Gaps = 6/85 (7%)
Query: 1700 YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLS 1759
Y+F F S+ +LFQ+ + GW V+ ++ L +PG+ SA + +
Sbjct: 1438 YDFDNFGASLFILFQIVSQEGWVDVMFETMSITGRGL------NPGDPTSAEFNAVFFVI 1491
Query: 1760 YLVISFLIVINMYIAVILENYSQAT 1784
+ +++ + ++ ++I+V + NY++ T
Sbjct: 1492 FNLLATVFILTLFISVFMRNYTEQT 1516
Score = 37.5 bits (83), Expect = 3.7
Identities = 24/96 (25%), Positives = 50/96 (52%), Gaps = 6/96 (6%)
Query: 833 LRVFKLAKSWP-TLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDR 891
LR++++ T +L++ ++G G +GNL + +I F+ A+ +QLF D +
Sbjct: 902 LRIYRVVMGVEITRSLIMLVLGNASG-IGNLVLFVFLITFLVAIFAVQLFRG---DIPAQ 957
Query: 892 FPDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWD 926
GD F +SF+ ++++L E W + +++
Sbjct: 958 DDGGDTITVTFATIFNSFLGLYQILSSENWTDILYN 993
>UniRef50_A6QWN8 Cluster: Putative uncharacterized protein; n=1;
Ajellomyces capsulatus NAm1|Rep: Putative uncharacterized
protein - Ajellomyces capsulatus NAm1
Length = 1952
Score = 102 bits (245), Expect = 9e-20
Identities = 98/419 (23%), Positives = 188/419 (44%), Gaps = 29/419 (6%)
Query: 1217 NTYFETAVITMILLSSLALALEDVHL--PHRPILQDILYYMDRIFTVIFFIEMLIKWLAL 1274
+ + A++ M+LL+ ++ L + H+P L + + D F ++F IE +IK +A
Sbjct: 1234 SAFLYAAIVAMVLLACVSSPLYQRNYLQTHKPGLSNWFVWTDLTFAILFTIEAVIKVIAD 1293
Query: 1275 GF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRM 1330
GF YF +W +D ++++ IN V+A+ A + + +ALR LR ++
Sbjct: 1294 GFFWTPNAYFRGSWGLIDGVVLVTLWINVVSAIFNATATS--RVVGAFKALRALRLLNVS 1351
Query: 1331 QGMRVVVNA-LVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMN--HTTLSH- 1386
R +A ++ + + V + F + FAI G+ LF G+ C D N H++L H
Sbjct: 1352 DSARETFHAVIILGGWKVISAAFVSMSFLVPFAIYGLNLFNGQLKSCNDDNFGHSSLDHC 1411
Query: 1387 --EIIPDKNAC-TLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGR 1443
E + A L N +FD+ G++ LFQ+ + +GW ++ ++ V +
Sbjct: 1412 VGEYMSSPYAWDVLAPRAVSNPYYSFDNFGESLFILFQIVSQEGWTGVLWQSMAITGVNQ 1471
Query: 1444 QPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYY 1503
QP + L+ L LF+ V + N+ EQ A F+T +Q+ +
Sbjct: 1472 QPEPLASQENGLFFIVFNLLGAVFVLTLFVSVFMRNYTEQTGVA------FLTAEQRSWL 1525
Query: 1504 NAMKKMGSKKPLK-AIPRPRWRPQAIVFEIVTDK--KFDMIIMLFIGLNMLTMTLDHYQQ 1560
K + P K +I + + ++ ++I K ++ I + ++L + L+ Y +
Sbjct: 1526 ELRKHLRQISPSKRSIDKDSSKIKSWCYKIAVKKHGRWSRFITALLLFHLLLLVLEFYPE 1585
Query: 1561 SETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDI 1619
S + D + ++ +SE L ++F NL V+F + ++ L+ I
Sbjct: 1586 SVWW----DRTRALLMIPRNSE-LDQLFKTAASSLTAIGNLLATWFVLFLVYAIALTQI 1639
Score = 71.3 bits (167), Expect = 2e-10
Identities = 49/218 (22%), Positives = 98/218 (44%), Gaps = 13/218 (5%)
Query: 1599 WNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFAL 1658
W+ F +++F +L LVL E + T R L ++ + L
Sbjct: 1563 WSRFITALLLFHLLLLVLEFYPESVWWDRT-----------RALLMIPRNSELDQLFKTA 1611
Query: 1659 AMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTS 1718
A SL A+ N+ F++ ++AI F K G + NF+ ++++LLF+ S
Sbjct: 1612 ASSLTAIGNLLATWFVLFLVYAIALTQIFGLTKFGKGENGNINFRDVPRALVLLFRTSAG 1671
Query: 1719 AGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILE 1778
GW+ +++ R +CGSA +S+ ++S I +++++++I E
Sbjct: 1672 EGWNEIMEDFATMAPPYCTAEGRFFESDCGSAVWARVLFISWNILSMYIFVSLFVSLIFE 1731
Query: 1779 NYSQATEDVQ--EGLTDDDYDMYYEIWQRFDPDGSQYI 1814
++S + ++ ++ + + W +DPDG+ YI
Sbjct: 1732 SFSYVYQRSSGLYAISREEIRRFKQAWATYDPDGTGYI 1769
Score = 62.5 bits (145), Expect = 1e-07
Identities = 67/261 (25%), Positives = 117/261 (44%), Gaps = 28/261 (10%)
Query: 173 FTGIY--TFESAVKVMARGFILQPFTYLRDAWNWLDFVVIA---LAYVTMGIDLGNLAAL 227
FTGI T S + F L + R ++ +DF+ + +++V + L + L
Sbjct: 506 FTGIQNTTDPSGDANSLQRFRLARRAFFRHSFTRIDFLAVVSYWISFVLSNLSLESGHHL 565
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLS----VFALMGLQIYMG 283
FR+L L+ + ++ GL + S+K +++ F + +FA++G+Q +
Sbjct: 566 YVFRMLSCLRILRLL-GLTNGTSVIFRSLKKAAPLLVHVAFLIGFFWLLFAIVGVQSFKS 624
Query: 284 VLTQKCVKVFPEDGSWGNLTD-ENWERFCQNETNWYGEGGDYPLCGNSSGAGQCE-PGYV 341
+ + CV V PE+ + L + +FC G G P AG + GY+
Sbjct: 625 SMRRTCVWVDPENQNNFTLNSAPDKIQFCGGYRE-VGTGASKPWILPDGRAGAVDAKGYL 683
Query: 342 CLQGF----GPNPNYGYTSFDTFGWAFLSAFRLMTQD-YWENLY----------QLFFVV 386
C +G G NP G SFD + F +M+ + + + LY LFFVV
Sbjct: 684 CPEGSLCVQGSNPYGGTISFDNVAHSLQLVFVVMSSNTFTDILYYMTDTDFLGAALFFVV 743
Query: 387 IIFLGSFYLVNLILAIVAMSY 407
+ S +LVNL++A++ S+
Sbjct: 744 SFVILSLWLVNLLVAVITSSF 764
Score = 55.2 bits (127), Expect = 2e-05
Identities = 48/244 (19%), Positives = 107/244 (43%), Gaps = 20/244 (8%)
Query: 1546 IGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFV 1605
IG ++ L ++D + +I + E L+ + ++F + N D
Sbjct: 812 IGFGLVVQCLRSSSMGHARRQLIDRTEIFVTIILAVEICLRFASDWRNFFRDARNCVDLA 871
Query: 1606 VVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPAL 1665
+I++ ++ +I S + + +V R+ R+V + L+ + ++ L
Sbjct: 872 ---HAIITCII--LIPPIRYSSRAYASLSIFQVLRIYRIVLAFSVMSDLIKTVFKNVVGL 926
Query: 1666 FNICLLLFLVMFIFAIFGMSFF---MHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWD 1722
N+ + +FL+ F+ +IF + F + +D G D F S + ++Q+ +S W
Sbjct: 927 LNLIIFVFLITFLASIFAVQLFRGQIPSQDMDGNDVQITFFDIYNSFLGMYQILSSENWT 986
Query: 1723 GVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQ 1782
+L + + P N G I +L+ + +++ +V+NM+IAVI E++
Sbjct: 987 SILYSAV----------QSTYPWNTG--WISAIFLIMWFILANFVVLNMFIAVIQESFDV 1034
Query: 1783 ATED 1786
+ ++
Sbjct: 1035 SEDE 1038
Score = 53.6 bits (123), Expect = 5e-05
Identities = 33/122 (27%), Positives = 60/122 (49%), Gaps = 5/122 (4%)
Query: 169 TEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA-- 226
T++ F ++T E+ +KV+A GF P Y R +W +D VV+ ++ + + N A
Sbjct: 1274 TDLTFAILFTIEAVIKVIADGFFWTPNAYFRGSWGLIDGVVLVTLWINVVSAIFNATATS 1333
Query: 227 --LRTFRVLRALKTVAIVPGLK-TIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
+ F+ LRAL+ + + + T +I + ++M L FA+ GL ++ G
Sbjct: 1334 RVVGAFKALRALRLLNVSDSARETFHAVIILGGWKVISAAFVSMSFLVPFAIYGLNLFNG 1393
Query: 284 VL 285
L
Sbjct: 1394 QL 1395
Score = 53.2 bits (122), Expect = 7e-05
Identities = 30/96 (31%), Positives = 49/96 (51%)
Query: 1274 LGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGM 1333
L + +F +++ +DF+ V+ I+FV + R L LR LR + G
Sbjct: 527 LARRAFFRHSFTRIDFLAVVSYWISFVLSNLSLESGHHLYVFRMLSCLRILRLLGLTNGT 586
Query: 1334 RVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
V+ +L +A P + +V + FWL+FAI+GVQ F
Sbjct: 587 SVIFRSLKKAAPLLVHVAFLIGFFWLLFAIVGVQSF 622
Score = 37.5 bits (83), Expect = 3.7
Identities = 21/85 (24%), Positives = 46/85 (54%), Gaps = 7/85 (8%)
Query: 1700 YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLS 1759
Y+F F +S+ +LFQ+ + GW GVL + N++ P S G+ +++
Sbjct: 1435 YSFDNFGESLFILFQIVSQEGWTGVL----WQSMAITGVNQQPEP--LASQENGLFFIV- 1487
Query: 1760 YLVISFLIVINMYIAVILENYSQAT 1784
+ ++ + V+ ++++V + NY++ T
Sbjct: 1488 FNLLGAVFVLTLFVSVFMRNYTEQT 1512
Score = 37.5 bits (83), Expect = 3.7
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 7/92 (7%)
Query: 845 LNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTD 904
L+ L ++ A+GNL ++ ++A+ Q+FG + +F G+ NF D
Sbjct: 1604 LDQLFKTAASSLTAIGNLLATWFVLFLVYAIALTQIFG------LTKFGKGENGNINFRD 1657
Query: 905 FMHSFMIVFRVLCGE-WIESMWDCMLVGDVSC 935
+ +++FR GE W E M D + C
Sbjct: 1658 VPRALVLLFRTSAGEGWNEIMEDFATMAPPYC 1689
Score = 37.1 bits (82), Expect = 4.9
Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 3/97 (3%)
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
R +F + DF+ V+ +S VLS++ + S L V R+ R+LRL+ G
Sbjct: 529 RRAFFRHSFTRIDFLAVVSYWISFVLSNLSLE---SGHHLYVFRMLSCLRILRLLGLTNG 585
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+ +L + P L ++ L+ +FAI G+ F
Sbjct: 586 TSVIFRSLKKAAPLLVHVAFLIGFFWLLFAIVGVQSF 622
>UniRef50_Q2HAK7 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized protein
- Chaetomium globosum (Soil fungus)
Length = 2098
Score = 101 bits (241), Expect = 3e-19
Identities = 121/563 (21%), Positives = 230/563 (40%), Gaps = 60/563 (10%)
Query: 1223 AVITMILLSSLALAL-EDVHLPHRPILQ-DILYYMDRIFTVIFFIEMLIKWLALGF---- 1276
A++ M++L+ + L + + P + + D F ++F +E IK +A GF
Sbjct: 1179 AIVAMVVLACVTTPLYQKEYFREHPFTPLNWFVWTDTAFAIVFTVEAFIKIIADGFFWTP 1238
Query: 1277 QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVV 1336
YF + W +D I+++ IN V AG I + + +ALR LR ++ R
Sbjct: 1239 NAYFRSTWGIIDAIVLVTLWINVVTLFTNAGAIS--RAVGAFKALRALRLLNVSDSARDT 1296
Query: 1337 VNALVQAIP-SIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNAC 1395
++L+ I + V + + FAI G+ LF GK C D + + + + N+
Sbjct: 1297 FHSLIIVGGWKILSAAFVSISLLIPFAIYGLNLFNGKLMMCNDGDGIVNLSDCVGEFNS- 1355
Query: 1396 TLENYTW--------ENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIR 1447
T N W +N NFD G + LFQ+ + +GW + A G QP
Sbjct: 1356 TPYNADWPMLAPRVADNPFFNFDDFGSSLFILFQIVSQEGWTDVSFAAQAITGKGLQPDG 1415
Query: 1448 ETNIYMY---LYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYN 1504
E L+ L LFI V + + EQ A F+T +Q+ +
Sbjct: 1416 EPPYGAQGNALFFVVFNLLATVFVLTLFISVFMRGYTEQTGVA------FLTAEQRSWLE 1469
Query: 1505 AMKKMGSKKPLKAI---PRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQS 1561
K + P K+ + +W+ I K+ + I + +++ + + Y++
Sbjct: 1470 LRKMLRQISPSKSAYDDKKNKWKMWCHKRAIEKRGKWYLAITTVLVFHLVLLLTEFYEEP 1529
Query: 1562 ETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIE 1621
++ V D +IF +I+ + ++++F L W + + +
Sbjct: 1530 VYWTQVKDICFLIFTLIYIANLIVRVFGL-------GWTRGEVTYIQ-----------LH 1571
Query: 1622 KYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAI 1681
K+F+ +L + + + + +L K A T + SL A + + L+F + +
Sbjct: 1572 KFFLVALVLML--IPRNDALDQLFKTAAASLTTI----GSLLATWIVFFLVFAIA-LTQT 1624
Query: 1682 FGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNER 1741
F ++ F +D N +T ++ILLF+ S GW+ V++ + + +
Sbjct: 1625 FSLTRFGSQEDAN-----INLRTVPHALILLFRFSCGEGWNEVMEDFAQVKPPFCVEGQT 1679
Query: 1742 GSPGNCGSATIGITYLLSYLVIS 1764
+CGS +++ +IS
Sbjct: 1680 FFDSDCGSTAWARVLFVAWNIIS 1702
Score = 59.7 bits (138), Expect = 8e-07
Identities = 68/314 (21%), Positives = 135/314 (42%), Gaps = 36/314 (11%)
Query: 1470 NLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIV 1529
NL I VI +F ++++ S F +D+ + ++ IPR + Q I
Sbjct: 690 NLLIAVITSSFQVIREESKASA--FTADDEPSLFQTN--------MEKIPRRKSALQRI- 738
Query: 1530 FEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFA 1589
F+ K + +L I + +L S++ ++ ++ + E LL+ +
Sbjct: 739 FD-----KTSWVWVLVITYGLFCQSLRSATMSQSRENFINASEIVVTSLLDVEILLRFLS 793
Query: 1590 LRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
+ +P NL D + + I +++L I S + + + ++ RV R+V
Sbjct: 794 NIRRFHHKPRNLIDLGLAV--ITTIILIPPIRN---SGQVYNWLTIFQIIRVYRVVLAIP 848
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF---MHVKDKGGLDDVYNFKTFV 1706
L+ + ++ + N+ + +FL+ F+ AIF F + D G F T
Sbjct: 849 MTSKLIELVLGNVTGIGNLMVFVFLITFLMAIFASQLFRGQLPATDDDGEYLRIPFNTIY 908
Query: 1707 QSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFL 1766
S + ++Q+ +S W +L + + +A IG +L+ + ++S+
Sbjct: 909 NSFLGMYQVLSSENWTDILYSVTSYTT------------QLNTAWIGAIFLIGWFILSYF 956
Query: 1767 IVINMYIAVILENY 1780
I+INM+IAVI EN+
Sbjct: 957 ILINMFIAVIQENF 970
Score = 52.4 bits (120), Expect = 1e-04
Identities = 32/122 (26%), Positives = 61/122 (50%), Gaps = 5/122 (4%)
Query: 169 TEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAY---VTMGIDLGNLA 225
T+ F ++T E+ +K++A GF P Y R W +D +V+ + VT+ + G ++
Sbjct: 1213 TDTAFAIVFTVEAFIKIIADGFFWTPNAYFRSTWGIIDAIVLVTLWINVVTLFTNAGAIS 1272
Query: 226 -ALRTFRVLRALKTVAIVPGLK-TIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
A+ F+ LRAL+ + + + T +I + +++ L FA+ GL ++ G
Sbjct: 1273 RAVGAFKALRALRLLNVSDSARDTFHSLIIVGGWKILSAAFVSISLLIPFAIYGLNLFNG 1332
Query: 284 VL 285
L
Sbjct: 1333 KL 1334
Score = 41.5 bits (93), Expect = 0.23
Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 2/108 (1%)
Query: 61 PQPDATLEQGLPLPVRMQGSFPLELASTPLEDI--DPFYHNQTTFVVISKGKDIFRFSAT 118
P PD + P+ + S+P +L TP E ++ + T + + +
Sbjct: 281 PSPDGRHPSRVSGPMLVDTSYPSQLFPTPTEKRPGSDYFQPEPTAPMPRRHGPLPNPLKG 340
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTV 166
N+L I P NPIR+ +LV P FI+ I+ IL+ + P V
Sbjct: 341 NSLGIFPPDNPIRKRLCDVLVSPWTEPFILVLIVAQAILLAVEAAPDV 388
Score = 41.1 bits (92), Expect = 0.30
Identities = 25/94 (26%), Positives = 50/94 (53%), Gaps = 4/94 (4%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
+RV+++ + P + LI ++ + +GNL + +I F+ A+ QLF + + D
Sbjct: 838 IRVYRVVLAIPMTSKLIELVLGNVTGIGNLMVFVFLITFLMAIFASQLF-RGQLPATD-- 894
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMW 925
DG+ R F +SF+ +++VL E W + ++
Sbjct: 895 DDGEYLRIPFNTIYNSFLGMYQVLSSENWTDILY 928
>UniRef50_Q9UDC3 Cluster: Neuronal-type voltage-gated CA2+ channel
class D alpha 1 subunit, VGCC class D alpha 1; n=21;
Theria|Rep: Neuronal-type voltage-gated CA2+ channel
class D alpha 1 subunit, VGCC class D alpha 1 - Homo
sapiens (Human)
Length = 293
Score = 100 bits (240), Expect = 3e-19
Identities = 64/169 (37%), Positives = 94/169 (55%), Gaps = 8/169 (4%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+R+ KLI + F ++ I+LSS ALA ED H IL Y D FT IF +E
Sbjct: 129 IRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHS-FRNTILGYFDYAFTAIFTVE 187
Query: 1267 MLIKWLALG--FQK--YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALR 1322
+L+K G K + N + LD ++V VSL++F + I K +R LR LR
Sbjct: 188 ILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQ---SSAISVVKILRVLRVLR 244
Query: 1323 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
PLRA++R +G++ VV + AI +I N+++V + +FA +GVQLF G
Sbjct: 245 PLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKG 293
Score = 70.9 bits (166), Expect = 3e-10
Identities = 45/176 (25%), Positives = 92/176 (52%), Gaps = 11/176 (6%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT---TPTVEST-----E 170
+A +IL NPIR ++ H +F+ I+ I+++ + + + +T +
Sbjct: 118 SAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFD 177
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTF 230
FT I+T E +K+ G L + R+ +N LD +V+ ++ V+ GI ++ ++
Sbjct: 178 YAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKIL 237
Query: 231 RVLRALKTVAIV---PGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
RVLR L+ + + GLK +V V +++ + +++I+T +FA +G+Q++ G
Sbjct: 238 RVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKG 293
Score = 60.1 bits (139), Expect = 6e-07
Identities = 44/163 (26%), Positives = 88/163 (53%), Gaps = 12/163 (7%)
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETF-SAVLDYLNMIFIVIFSSECLLKI-- 1587
+++ F +I++FI L+ + + +S +F + +L Y + F IF+ E LLK+
Sbjct: 135 KLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTT 194
Query: 1588 FALRYH---YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRL 1644
F H + +NL D +VV S++S I+ +S +++++RV +V R LR
Sbjct: 195 FGAFLHKGAFCRNYFNLLDMLVVGVSLVSFG----IQSSAIS--VVKILRVLRVLRPLRA 248
Query: 1645 VKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+ AKG++ ++ + +++ + NI ++ L+ F+FA G+ F
Sbjct: 249 INRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLF 291
>UniRef50_UPI00006CBCBD Cluster: cation channel family protein; n=1;
Tetrahymena thermophila SB210|Rep: cation channel family
protein - Tetrahymena thermophila SB210
Length = 1806
Score = 99.5 bits (237), Expect = 8e-19
Identities = 67/279 (24%), Positives = 133/279 (47%), Gaps = 20/279 (7%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
L+++ YFE ++I +I S + + + D + + Y+D I VIF IE ++K LA
Sbjct: 1002 LLKSKYFENSIIFLIFSSCIIMGISDPLRDPNSTTEKTIRYLDIIIVVIFIIEGVLKMLA 1061
Query: 1274 LGF-----QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMS 1328
G Y N W +D +++S+ F A + M RA+R ++
Sbjct: 1062 YGIYNKNRDSYLKNGWNIIDLTSIIISVCVFFFP-------DALRFMNGFRAIRIIKLSK 1114
Query: 1329 RMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEI 1388
+M + +V+ +++++IP++ + L+ FA+ ++ F GKY++C ++ T+S+
Sbjct: 1115 KMSSVEIVLISIIKSIPTVAKLSLLAFASLTFFALFPLKYFKGKYYQCANL---TVSN-- 1169
Query: 1389 IPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSR--EVGRQPI 1446
I K C W + +D++ ++ +F ++T +GW +M A ++ ++ P
Sbjct: 1170 ISTKWDCMDTGGDWVPQDLRWDNIIRSTYNMFIISTCEGWSFMMQQAYNATNVQINSIPG 1229
Query: 1447 RETNIYMY-LYXXXXXXXXXXXTLNLFIGVIIDNFNEQK 1484
T + ++ N FIGV+I+ FN+ K
Sbjct: 1230 LSTQAKDWSIFFVFSFVVGNKMVFNSFIGVMIEKFNQIK 1268
Score = 75.8 bits (178), Expect = 1e-11
Identities = 55/254 (21%), Positives = 114/254 (44%), Gaps = 18/254 (7%)
Query: 1583 CLLKIFA---LRYHYFVEPWNLFDFVVVMFSILSLVLSDII--EKYFVSPTLLRVVRVAK 1637
CL IF + + WN F+ + +FS L L + Y ++ L ++V +
Sbjct: 1304 CLCSIFIEWMINIKQYQSVWNCFEVFLFLFSFAGLFLKFYFKTDSYEIN-ALFNFMQVIR 1362
Query: 1638 VGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLD 1697
R++ + A LL + + LP++ I + V+FI+ + G++ F ++K + ++
Sbjct: 1363 SCRIVLVFNSAL---ELLGTITLVLPSVGPIAIFFCFVLFIWTLIGLNLFPYLKPQQYIN 1419
Query: 1698 DV-YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEE----C----DLPDNERGSPGNCG 1748
+F+ F ++ L +++ S W G++ E++ C + E CG
Sbjct: 1420 GFDLSFRDFTSTVATLIRVAQSEFWFGLVVDAGREQQPNFVCFNVSSYAEFEIHGFSGCG 1479
Query: 1749 SATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDP 1808
G Y S+ +I ++++N+ +A+I++ ++A + L D ++W +D
Sbjct: 1480 HELSGFIYFFSFHLIVSIMIVNLLLALIIDGSAEAFKIQDAALNRYQLDQIQDLWMEYDK 1539
Query: 1809 DGSQYIRYDQLSDF 1822
DG +I Y F
Sbjct: 1540 DGQGFINYKDFWQF 1553
Score = 56.0 bits (129), Expect = 1e-05
Identities = 59/279 (21%), Positives = 111/279 (39%), Gaps = 42/279 (15%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDH--YQQSETFSAVLDYLNMIFIVIFSSECLLKIFA 1589
++ K F+ I+ I + + M + + T + YL++I +VIF E +LK+ A
Sbjct: 1002 LLKSKYFENSIIFLIFSSCIIMGISDPLRDPNSTTEKTIRYLDIIIVVIFIIEGVLKMLA 1061
Query: 1590 L------RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLR 1643
R Y WN+ D ++ S+ F P LR + + R+++
Sbjct: 1062 YGIYNKNRDSYLKNGWNIIDLTSIIISVC----------VFFFPDALRFMNGFRAIRIIK 1111
Query: 1644 LVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF---------------- 1687
L K + +L ++ S+P + + LL F + FA+F + +F
Sbjct: 1112 LSKKMSSVEIVLISIIKSIPTVAKLSLLAFASLTFFALFPLKYFKGKYYQCANLTVSNIS 1171
Query: 1688 --MHVKDKGG--LDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGS 1743
D GG + + ++S +F +ST GW ++ N +
Sbjct: 1172 TKWDCMDTGGDWVPQDLRWDNIIRSTYNMFIISTCEGWSFMMQQAYNATNVQI----NSI 1227
Query: 1744 PGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQ 1782
PG A + + V+ +V N +I V++E ++Q
Sbjct: 1228 PGLSTQAKDWSIFFVFSFVVGNKMVFNSFIGVMIEKFNQ 1266
Score = 55.6 bits (128), Expect = 1e-05
Identities = 43/163 (26%), Positives = 78/163 (47%), Gaps = 11/163 (6%)
Query: 1216 ENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALG 1275
E+ YF ++I+ + + L + P + LQ L D I T++F IE++I+ +
Sbjct: 534 ESGYFNLFSYSIIIANYIVLCCDKY--PIKDSLQKNLILADSILTILFLIEVIIRIFSQK 591
Query: 1276 FQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGI-------QAF-KTMRTLRALRPLRAM 1327
Q +FTN DF+I++ ++I F + QA K ++ R R L M
Sbjct: 592 KQ-FFTNLIDLADFVILIANIIMFSVGFAQGQNMFSSETQEQAIIKCLKGWRIFRILLEM 650
Query: 1328 SRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
+ + + +++ A + +F ++ IF L F I+G+ LFA
Sbjct: 651 TVLYPLGILIEAFFKTFVGLFYHTIIVAIFVLAFGILGMNLFA 693
Score = 50.0 bits (114), Expect = 6e-04
Identities = 30/123 (24%), Positives = 63/123 (51%), Gaps = 2/123 (1%)
Query: 162 TTPTVESTEVIFTGIYTFESAVKVMARG-FILQPFTYLRDAWNWLDFVVIALAYVTMGID 220
T T+ ++I I+ E +K++A G + +YL++ WN +D I ++ V +
Sbjct: 1036 TEKTIRYLDIIIVVIFIIEGVLKMLAYGIYNKNRDSYLKNGWNIIDLTSIIIS-VCVFFF 1094
Query: 221 LGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
L + FR +R +K + ++ ++ ++I+S+ + + +L SL+ FAL L+
Sbjct: 1095 PDALRFMNGFRAIRIIKLSKKMSSVEIVLISIIKSIPTVAKLSLLAFASLTFFALFPLKY 1154
Query: 281 YMG 283
+ G
Sbjct: 1155 FKG 1157
Score = 46.4 bits (105), Expect = 0.008
Identities = 41/200 (20%), Positives = 86/200 (43%), Gaps = 16/200 (8%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVE 1597
F++ I N + + D Y ++ L + I ++F E +++IF+ + +F
Sbjct: 538 FNLFSYSIIIANYIVLCCDKYPIKDSLQKNLILADSILTILFLIEVIIRIFSQKKQFFTN 597
Query: 1598 PWNLFDFVV-----VMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIR 1652
+L DFV+ +MFS+ ++ +++ ++ ++ R+L + +
Sbjct: 598 LIDLADFVILIANIIMFSVGFAQGQNMFSSETQEQAIIKCLKGWRIFRILLEMTVLYPLG 657
Query: 1653 TLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMH-------VK----DKGGLDDVYN 1701
L+ A + LF +++ + + F I GM+ F + VK K G ++N
Sbjct: 658 ILIEAFFKTFVGLFYHTIIVAIFVLAFGILGMNLFAYRARFEEEVKLAHDPKEGKSYIFN 717
Query: 1702 FKTFVQSMILLFQMSTSAGW 1721
F TF S+I + + W
Sbjct: 718 FDTFGNSIITVILCFLNEEW 737
Score = 45.2 bits (102), Expect = 0.018
Identities = 30/150 (20%), Positives = 71/150 (47%), Gaps = 11/150 (7%)
Query: 249 VGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWE 308
+ ++I ++ L +++ + ++++AL+GL I+ G L +C F + + L + +
Sbjct: 286 LNSLISTLPELYKIVLGLLAIMTIYALIGLHIFQGALEFRCR--FESEPTPDGLFEAD-- 341
Query: 309 RFCQNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAF 368
+++ N G + + + + + N +YG FD FGW+ + F
Sbjct: 342 ---ESQINLCGRQSGCKENTYCRAPFEYDVPFHAEESYLENLDYGVVKFDHFGWSLFTVF 398
Query: 369 RLMTQDYWENLYQL---FFVVI-IFLGSFY 394
++ W ++ L F++++ +FLG+ Y
Sbjct: 399 HIVESIGWSSIILLVLGFYIILNLFLGALY 428
>UniRef50_Q22N11 Cluster: Cation channel family protein; n=1;
Tetrahymena thermophila SB210|Rep: Cation channel family
protein - Tetrahymena thermophila SB210
Length = 1879
Score = 96.7 bits (230), Expect = 6e-18
Identities = 81/290 (27%), Positives = 134/290 (46%), Gaps = 9/290 (3%)
Query: 1215 IENT-YFETAVITMILLSSLALALED-VHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
IEN+ YF +I + + ++ LA + + P+ ++ L ++ I VI+F E LIK +
Sbjct: 905 IENSPYFINFLIFLTVANTALLAAQSRLDDPNSTKIKT-LRALEMITMVIYFFEALIKII 963
Query: 1273 ALGFQKYFTNAWC-WLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQ 1331
A GF N++ I + LI + +L F+T+RTL
Sbjct: 964 ARGFLLNGPNSYMRQFKNIYDLFLLITQIISLLVYPDYVIFRTLRTLNLFH---LSKYFV 1020
Query: 1332 GMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPD 1391
G+RV++ +L Q++P+I +LL ++FAI+ ++ GK + C + L E I
Sbjct: 1021 GVRVMLVSLSQSVPTILRLLLFTFCILIVFAIIPMKQLKGKMYYCASLEREKL--ESIHS 1078
Query: 1392 KNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNI 1451
K C E W N+ N+D+V + LF +A+ +GW +M A D+R V P +
Sbjct: 1079 KQDCLDEGGDWLNNLQNWDNVLFSLFNLFIMASCEGWSILMGQANDARGVDLNPQQNQEK 1138
Query: 1452 YMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKK 1501
+Y N F GV+I+ + E KKK E+ +D K
Sbjct: 1139 EWSVYFIIYFILGNIMLFNAFTGVMIEKYIEIKKKFALQQEIVHVKDATK 1188
Score = 90.6 bits (215), Expect = 4e-16
Identities = 68/306 (22%), Positives = 146/306 (47%), Gaps = 20/306 (6%)
Query: 1529 VFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIF 1588
++ ++ K + M + I L+ + L++++ + + +L L F++I+ E LKI+
Sbjct: 1252 LYILINHKHYKMCMDTCIILSTICFALNYWRAPDLYEQILRNL---FLIIYIIEIGLKIY 1308
Query: 1589 ALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIE-KYFV--SPTLLRVVRVAKVGRVLRLV 1645
++ +F + +F+ ++V S++ L++ ++ K F ++ + V RVLRL
Sbjct: 1309 TEKFLFFASRFQIFELIMVSLSLVYLIMQGTLDMKDFKIHHREIVLCMEFISVFRVLRLA 1368
Query: 1646 KGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDV-YNFKT 1704
K ++ L L LP + + LL +++++A+ GM F +K + L+ +FKT
Sbjct: 1369 KTITIVKKTLNILFYILPEIAPVAGLLLYLIYMYALIGMQIFPFIKVQNTLNGYDQHFKT 1428
Query: 1705 FVQSMILLFQMSTSAGWDGVLDGIINEEE----CDLPDNERGSPGN----CGSATIGITY 1756
F ++ L ++++ W V++ + +++ C N N CG+ G Y
Sbjct: 1429 FNTAVFTLIRVASGEQWFYVVNDAVRQQQPNFVCQTISNYDDYINNGLNGCGTYW-GYIY 1487
Query: 1757 LLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRY 1816
S+ + +I++N++IAV+LE ++ E+W +D G +I Y
Sbjct: 1488 FFSFHLFVSVIILNLFIAVLLE----LIIGQNTAMSKYQLSKIKELWSEYDKQGYGFINY 1543
Query: 1817 DQLSDF 1822
+ +F
Sbjct: 1544 EDFWEF 1549
Score = 52.0 bits (119), Expect = 2e-04
Identities = 31/120 (25%), Positives = 63/120 (52%), Gaps = 2/120 (1%)
Query: 165 TVESTEVIFTGIYTFESAVKVMARGFILQ-PFTYLRDAWNWLDFVVIALAYVTMGIDLGN 223
T+ + E+I IY FE+ +K++ARGF+L P +Y+R N D ++ +++ + +
Sbjct: 942 TLRALEMITMVIYFFEALIKIIARGFLLNGPNSYMRQFKNIYDLFLLITQIISL-LVYPD 1000
Query: 224 LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
RT R L G++ ++ ++ +SV + +++ T L VFA++ ++ G
Sbjct: 1001 YVIFRTLRTLNLFHLSKYFVGVRVMLVSLSQSVPTILRLLLFTFCILIVFAIIPMKQLKG 1060
Score = 48.4 bits (110), Expect = 0.002
Identities = 58/241 (24%), Positives = 109/241 (45%), Gaps = 50/241 (20%)
Query: 1571 LNMIFIVIFSSECLLKIFALRY------HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYF 1624
L MI +VI+ E L+KI A + Y + N++D +++ I+SL+
Sbjct: 946 LEMITMVIYFFEALIKIIARGFLLNGPNSYMRQFKNIYDLFLLITQIISLL--------- 996
Query: 1625 VSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIF-- 1682
V P + + R + + L K G+R +L +L+ S+P + + L F ++ +FAI
Sbjct: 997 VYPDYV-IFRTLRTLNLFHLSKYFVGVRVMLVSLSQSVPTILRLLLFTFCILIVFAIIPM 1055
Query: 1683 ----GMSFF-----------MHVK----DKGG--LDDVYNFKTFVQSMILLFQMSTSAGW 1721
G ++ +H K D+GG L+++ N+ + S+ LF M++ GW
Sbjct: 1056 KQLKGKMYYCASLEREKLESIHSKQDCLDEGGDWLNNLQNWDNVLFSLFNLFIMASCEGW 1115
Query: 1722 DGVLDGIINEEE-CDL-PDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILEN 1779
+L G N+ DL P + + Y + Y ++ +++ N + V++E
Sbjct: 1116 -SILMGQANDARGVDLNPQQNQEKEWS--------VYFIIYFILGNIMLFNAFTGVMIEK 1166
Query: 1780 Y 1780
Y
Sbjct: 1167 Y 1167
Score = 46.0 bits (104), Expect = 0.011
Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Query: 176 IYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA----LRTFR 231
I+ + ++++ RGF Q + ++ W+ +F + L+ V +G G+L A LR
Sbjct: 345 IFVSDIILQIIYRGFWKQKNAFFKNPWHLFNFFSV-LSSVIVGF-TGSLNAFSIILRVLG 402
Query: 232 VLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKC 289
+LR LK + + K + I SV L + II + F ++GL I+ G L +C
Sbjct: 403 MLRPLKLIYHIKPYKKQLERFIRSVSLLGESIIRLFIFMVFFTILGLNIFKGSLEYRC 460
Score = 44.0 bits (99), Expect = 0.042
Identities = 31/133 (23%), Positives = 66/133 (49%), Gaps = 11/133 (8%)
Query: 1262 IFFIEMLIKWLALGFQK----YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKT-MR 1316
IF +++++ + GF K +F N W +F V+ S+I + G + AF +R
Sbjct: 345 IFVSDIILQIIYRGFWKQKNAFFKNPWHLFNFFSVLSSVI-----VGFTGSLNAFSIILR 399
Query: 1317 TLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY-FK 1375
L LRPL+ + ++ + + ++++ + ++ IF + F I+G+ +F G ++
Sbjct: 400 VLGMLRPLKLIYHIKPYKKQLERFIRSVSLLGESIIRLFIFMVFFTILGLNIFKGSLEYR 459
Query: 1376 CVDMNHTTLSHEI 1388
C + + + EI
Sbjct: 460 CRETPNPPENSEI 472
Score = 43.2 bits (97), Expect = 0.074
Identities = 46/191 (24%), Positives = 82/191 (42%), Gaps = 26/191 (13%)
Query: 1511 SKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHY---------QQS 1561
S+KP + + W+ +F + K+++ + LN+L +D Y + S
Sbjct: 274 SQKPPEQL---HWKDNLKIF--LKSKRYNTFFIALSLLNLLAFMVDDYSSRRPTGATENS 328
Query: 1562 ETFSAVLDYLNMIFIVIFSSECLLKI-----FALRYHYFVEPWNLFDFVVVMFSILSLVL 1616
S + + IF S+ +L+I + + +F PW+LF+F FS+LS V+
Sbjct: 329 NLRSTFAETIQFSCSFIFVSDIILQIIYRGFWKQKNAFFKNPWHLFNF----FSVLSSVI 384
Query: 1617 SDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVM 1676
+LRV+ + R L+L+ K + L S+ L + LF+ M
Sbjct: 385 VGFTGSLNAFSIILRVLGML---RPLKLIYHIKPYKKQLERFIRSVSLLGESIIRLFIFM 441
Query: 1677 FIFAIFGMSFF 1687
F I G++ F
Sbjct: 442 VFFTILGLNIF 452
Score = 40.7 bits (91), Expect = 0.40
Identities = 41/171 (23%), Positives = 81/171 (47%), Gaps = 16/171 (9%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
LR + LI + +++ + T I+LS++ AL P + + IL +F +I+ IE
Sbjct: 1248 LRHYLYILINHKHYKMCMDTCIILSTICFALNYWRAPD--LYEQILR---NLFLIIYIIE 1302
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKT--------MRTL 1318
+ +K F +F + + + I+V +SL+ + + G ++ FK M +
Sbjct: 1303 IGLKIYTEKFL-FFASRFQIFELIMVSLSLVYLI--MQGTLDMKDFKIHHREIVLCMEFI 1359
Query: 1319 RALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
R LR + ++ +N L +P I V + L ++A++G+Q+F
Sbjct: 1360 SVFRVLRLAKTITIVKKTLNILFYILPEIAPVAGLLLYLIYMYALIGMQIF 1410
>UniRef50_Q65MK7 Cluster: Putative uncharacterized protein; n=1;
Bacillus licheniformis ATCC 14580|Rep: Putative
uncharacterized protein - Bacillus licheniformis (strain
DSM 13 / ATCC 14580)
Length = 276
Score = 96.3 bits (229), Expect = 8e-18
Identities = 68/269 (25%), Positives = 133/269 (49%), Gaps = 37/269 (13%)
Query: 1522 RWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSS 1581
R+ Q+ V ++ + F I I LN +++ L+ Y + + V ++ +F+ IF
Sbjct: 7 RYSVQSKVSALINCRLFQSFITTVIVLNAISIGLETYAFFKPYQKVFFIVDCLFLTIFVI 66
Query: 1582 ECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRV 1641
E LK+F + H+F WN+FDFV+V S++ + FVS V+R+ +V RV
Sbjct: 67 ELSLKLFVQKQHFFKNNWNVFDFVIVAGSLI------LYNTNFVS-----VLRIFRVLRV 115
Query: 1642 LRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYN 1701
LR + +R ++ AL M++P + ++ +L+ ++ +++A+ G FF + +
Sbjct: 116 LRTITSVPSLRRIVNALFMAIPTISSVIILMSIIFYVYAVIGTMFFSAIAPE-------Y 168
Query: 1702 FKTFVQSMILLFQMSTSAGW-DGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSY 1760
F S++ LFQ T W G+ I E G + + Y +S+
Sbjct: 169 FGNLQLSLLTLFQTFTLESWASGIFRPIFAES---------------GWSWL---YFVSF 210
Query: 1761 LVISFLIVINMYIAVILENYSQATEDVQE 1789
+VI+ I+IN+ + I+ N + ++++++
Sbjct: 211 IVIATFIMINLIVGEIVNNAQKISQEIED 239
Score = 82.6 bits (195), Expect = 1e-13
Identities = 55/182 (30%), Positives = 100/182 (54%), Gaps = 14/182 (7%)
Query: 1206 TLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFI 1265
+++ K LI F++ + T+I+L+++++ LE + +P Q + + +D +F IF I
Sbjct: 9 SVQSKVSALINCRLFQSFITTVIVLNAISIGLE-TYAFFKPY-QKVFFIVDCLFLTIFVI 66
Query: 1266 EMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLR 1325
E+ +K L + Q +F N W DF+IV SLI + +R R LR LR
Sbjct: 67 ELSLK-LFVQKQHFFKNNWNVFDFVIVAGSLILY--------NTNFVSVLRIFRVLRVLR 117
Query: 1326 AMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF---AGKYFKCVDMNHT 1382
++ + +R +VNAL AIP+I +V+++ I + ++A++G F A +YF + ++
Sbjct: 118 TITSVPSLRRIVNALFMAIPTISSVIILMSIIFYVYAVIGTMFFSAIAPEYFGNLQLSLL 177
Query: 1383 TL 1384
TL
Sbjct: 178 TL 179
Score = 66.9 bits (156), Expect = 5e-09
Identities = 40/145 (27%), Positives = 74/145 (51%), Gaps = 4/145 (2%)
Query: 142 LFSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKV--MARGFILQPFTYLR 199
LF FI T I++N I + + T + + +F + + V ++ +Q + +
Sbjct: 22 LFQSFITTVIVLNAISIGLETYAFFKPYQKVFFIVDCLFLTIFVIELSLKLFVQKQHFFK 81
Query: 200 DAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNL 259
+ WN DFV++A + + + ++ LR FRVLR L+T+ VP L+ IV A+ ++ +
Sbjct: 82 NNWNVFDFVIVAGSLILYNTNF--VSVLRIFRVLRVLRTITSVPSLRRIVNALFMAIPTI 139
Query: 260 RDVIILTMFSLSVFALMGLQIYMGV 284
VIIL V+A++G + +
Sbjct: 140 SSVIILMSIIFYVYAVIGTMFFSAI 164
>UniRef50_A3EY19 Cluster: Cardiac sodium channel alpha subunit
variant; n=21; Coelomata|Rep: Cardiac sodium channel
alpha subunit variant - Homo sapiens (Human)
Length = 102
Score = 93.5 bits (222), Expect = 5e-17
Identities = 41/89 (46%), Positives = 62/89 (69%)
Query: 1526 QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLL 1585
Q +F+IVT + FD+ IM I LNM+TM ++ QS +L +N++F+ IF+ EC++
Sbjct: 4 QGFIFDIVTKQAFDVTIMFLICLNMVTMMVETDDQSPEKINILAKINLLFVAIFTGECIV 63
Query: 1586 KIFALRYHYFVEPWNLFDFVVVMFSILSL 1614
K+ ALR++YF WN+FDFVVV+ SI+ L
Sbjct: 64 KLAALRHYYFTNSWNIFDFVVVILSIVEL 92
Score = 43.6 bits (98), Expect = 0.056
Identities = 25/87 (28%), Positives = 49/87 (56%), Gaps = 5/87 (5%)
Query: 1212 FKLIENTYFETAVITMILLSSLALALE-DVHLPHRPILQDILYYMDRIFTVIFFIEMLIK 1270
F ++ F+ ++ +I L+ + + +E D P + +IL ++ +F IF E ++K
Sbjct: 8 FDIVTKQAFDVTIMFLICLNMVTMMVETDDQSPEKI---NILAKINLLFVAIFTGECIVK 64
Query: 1271 WLALGFQKYFTNAWCWLDFIIVMVSLI 1297
AL YFTN+W DF++V++S++
Sbjct: 65 LAALRHY-YFTNSWNIFDFVVVILSIV 90
>UniRef50_UPI0000ECA7B2 Cluster: Voltage-dependent N-type calcium
channel subunit alpha-1B (Voltage- gated calcium channel
subunit alpha Cav2.2) (CHCACHA1B); n=2; Euteleostomi|Rep:
Voltage-dependent N-type calcium channel subunit alpha-1B
(Voltage- gated calcium channel subunit alpha Cav2.2)
(CHCACHA1B) - Gallus gallus
Length = 168
Score = 93.1 bits (221), Expect = 7e-17
Identities = 52/175 (29%), Positives = 101/175 (57%), Gaps = 9/175 (5%)
Query: 1604 FVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLP 1663
FV V+ SI +++++I + F++ + LR+ R A R+++L++ IR LL+ S
Sbjct: 1 FVTVLGSITDILVTEIADN-FINLSFLRLFRAA---RLIKLLRQGYTIRILLWTFVQSFK 56
Query: 1664 ALFNICLLLFLVMFIFAIFGMSFFMHV--KDKGGLDDVYNFKTFVQSMILLFQMSTSAGW 1721
AL +CLL+ ++ FI+AI GM F ++ D+ ++ NF+TF+Q+++LLF+ +T W
Sbjct: 57 ALPYVCLLIAMLFFIYAIIGMQVFGNIALNDETSINRHNNFRTFLQALMLLFRSATGEAW 116
Query: 1722 DGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVI 1776
++ ++ CD + CGS Y +S++ + +++N+++AVI
Sbjct: 117 HEIMLSCLSNRACDPLSGL--TKNECGS-DFAYFYFVSFIFLCSFLMLNLFVAVI 168
Score = 47.2 bits (107), Expect = 0.005
Identities = 28/97 (28%), Positives = 53/97 (54%), Gaps = 7/97 (7%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
R+ KL + T+ +L+ ++ AL + ++ ++ FI+A++GMQ+FG ++
Sbjct: 33 RLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALN-----D 87
Query: 894 DGDLPRW-NFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
+ + R NF F+ + M++FR GE W E M C+
Sbjct: 88 ETSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCL 124
>UniRef50_O73707 Cluster: Voltage-dependent L-type calcium channel
subunit alpha-1C; n=7; Euteleostomi|Rep:
Voltage-dependent L-type calcium channel subunit alpha-1C
- Gallus gallus (Chicken)
Length = 177
Score = 92.7 bits (220), Expect = 9e-17
Identities = 49/177 (27%), Positives = 103/177 (58%), Gaps = 6/177 (3%)
Query: 1605 VVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPA 1664
++V+ SI+ + ++++ S + R+ +V R+++L+ +GIRTLL+ S A
Sbjct: 2 LIVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQA 61
Query: 1665 LFNICLLLFLVMFIFAIFGMSFF--MHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWD 1722
L + LL+ ++ FI+A+ GM F + + D ++ NF+TF Q+++LLF+ +T W
Sbjct: 62 LPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQ 121
Query: 1723 GVLDGIINEEECD---LPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVI 1776
++ + +++CD P N + +CGS + + Y +S+ ++ ++I++++AVI
Sbjct: 122 EIMLACLPDKKCDPDSEPANSTEADHSCGS-SFAVFYFISFYMLCAFLIIDLFVAVI 177
Score = 44.4 bits (100), Expect = 0.032
Identities = 30/106 (28%), Positives = 52/106 (49%), Gaps = 7/106 (6%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
+R+ KL + L+ ++ AL + ++ ++ FI+AV+GMQ+FGK ++
Sbjct: 36 MRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEI 95
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSCIP 937
+ NF F + +++FR GE W E M C+ D C P
Sbjct: 96 NRNN----NFQTFPQAVLLLFRCATGEAWQEIMLACL--PDKKCDP 135
Score = 39.1 bits (87), Expect = 1.2
Identities = 33/117 (28%), Positives = 61/117 (52%), Gaps = 23/117 (19%)
Query: 1316 RTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK 1375
R R +R ++ +SR +G+R ++ +++ ++ V L+ ++ + I+A++G+Q+F GK
Sbjct: 31 RLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVF-GK--- 86
Query: 1376 CVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIM 1432
+ +N TT EI N NF +A L LF+ AT + W +IM
Sbjct: 87 -IALNDTT---EI---------------NRNNNFQTFPQAVLLLFRCATGEAWQEIM 124
>UniRef50_Q22N13 Cluster: Cation channel family protein; n=1;
Tetrahymena thermophila SB210|Rep: Cation channel family
protein - Tetrahymena thermophila SB210
Length = 1152
Score = 91.1 bits (216), Expect = 3e-16
Identities = 61/246 (24%), Positives = 121/246 (49%), Gaps = 13/246 (5%)
Query: 1209 LKTFKLIENTY-FETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEM 1267
+K K IE+ + FE ++ +I+++ + +A++ L H + ++ ++ FT I+ E+
Sbjct: 908 IKICKKIEDDHRFENFIMFIIIINIIVMAIDSPLLDHHDPTKIAIHNLEIFFTSIYGSEI 967
Query: 1268 LIKWLALG-FQK--YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPL 1324
LIK +A G FQK Y + DF + +++ F+ + + LRA +
Sbjct: 968 LIKIIACGLFQKGGYLREPKNYFDFSLFCLNIAGFIFS-------SKLAILNALRAFHIV 1020
Query: 1325 RAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTL 1384
+ +R+++ +L Q++P +F +L F L+FAI+ ++L GK + CV ++ L
Sbjct: 1021 VLSKHFESLRIILVSLYQSLPYLFKLLFFSTCFLLVFAIIPLRLLKGKMYNCVTIDQAQL 1080
Query: 1385 SHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQ 1444
++ + C W ++D++ + LF +A+ +GW N A D+ + Q
Sbjct: 1081 M--LVNSQIDCLDLGGDWVKDDFHYDNMLYSLFNLFIIASCEGWSYFSNKAQDTVGLNLQ 1138
Query: 1445 PIRETN 1450
PI N
Sbjct: 1139 PIEGYN 1144
Score = 56.4 bits (130), Expect = 7e-06
Identities = 85/412 (20%), Positives = 162/412 (39%), Gaps = 50/412 (12%)
Query: 1309 IQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQL 1368
I A K++ R + ++ S + + ++ I +F +++ + + ++FA++G L
Sbjct: 713 IHAIKSINVFRIFQVVKNTSFFRTVNHLIIYFYDTICELFYFIVIIVFYCVLFALIGENL 772
Query: 1369 FAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGW 1428
FA FK +N +I DK+ ++ +N+D+ ++ + W
Sbjct: 773 FA---FKAQFIN----GDQIPEDKSM-------GQSPRINYDNFFSSFEATILNILNEQW 818
Query: 1429 IQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAG 1488
M + + R +G Y + + LFI + +FN ++K
Sbjct: 819 NVSMYNYM--RSIGDYVCT----YWIIVISTGEIFIIKLLMALFINTFLKHFNNRQKDHN 872
Query: 1489 GSLEMFMTED--QKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFI 1546
+ E + + NA + K I +I D +F+ IM I
Sbjct: 873 DAKEEAQINQIVRTQVQNAKTQHSEHKN----NHKECFLIKICKKIEDDHRFENFIMFII 928
Query: 1547 GLNMLTMTLDH--YQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL----RYHYFVEPWN 1600
+N++ M +D + + L + F I+ SE L+KI A + Y EP N
Sbjct: 929 IINIIVMAIDSPLLDHHDPTKIAIHNLEIFFTSIYGSEILIKIIACGLFQKGGYLREPKN 988
Query: 1601 LFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAM 1660
FDF + +I + S + L ++ + ++ L K + +R +L +L
Sbjct: 989 YFDFSLFCLNIAGFIFS----------SKLAILNALRAFHIVVLSKHFESLRIILVSLYQ 1038
Query: 1661 SLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILL 1712
SLP LF + + +FAI + KG +YN T Q+ ++L
Sbjct: 1039 SLPYLFKLLFFSTCFLLVFAIIPLRLL-----KG---KMYNCVTIDQAQLML 1082
Score = 54.0 bits (124), Expect = 4e-05
Identities = 46/161 (28%), Positives = 78/161 (48%), Gaps = 16/161 (9%)
Query: 143 FSLFIITTILVNCILMIM---------PTTPTVESTEVIFTGIYTFESAVKVMARGFILQ 193
F FI+ I++N I+M + PT + + E+ FT IY E +K++A G + Q
Sbjct: 920 FENFIMFIIIINIIVMAIDSPLLDHHDPTKIAIHNLEIFFTSIYGSEILIKIIACG-LFQ 978
Query: 194 PFTYLRDAWNWLDFVVIAL--AYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGA 251
YLR+ N+ DF + L A L L ALR F ++ K L+ I+ +
Sbjct: 979 KGGYLREPKNYFDFSLFCLNIAGFIFSSKLAILNALRAFHIVVLSKH---FESLRIILVS 1035
Query: 252 VIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKV 292
+ +S+ L ++ + L VFA++ L++ G + CV +
Sbjct: 1036 LYQSLPYLFKLLFFSTCFLLVFAIIPLRLLKGKM-YNCVTI 1075
Score = 50.8 bits (116), Expect = 4e-04
Identities = 47/200 (23%), Positives = 84/200 (42%), Gaps = 20/200 (10%)
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQ 287
R F +LR ++ + ++ LK + S+ + I + ++ +A++GL I+MG +
Sbjct: 181 RIFAMLRPMRILQMITPLKLQFDRLFRSIPKINLSIWRILIFMAFYAIVGLHIFMGDVEY 240
Query: 288 KC-VKVFPEDGSWGNLTDENWERFCQNETN---WYGEGGDYPLCGN----SSGAGQCEPG 339
+C V P G + N+ W LCG +
Sbjct: 241 RCRVTSDPPPNENGKNLSNTFYMLIFNKLKIDEWQIYEEIPYLCGRWECPEESPYDYDRP 300
Query: 340 YVCLQGFGPNPNYGYTSFDTFGWAFLSAFRL--------MTQDYWEN----LYQLFFVVI 387
Y Q N NYGYT FD FG ++ + F + +T YW + + +F+ +
Sbjct: 301 YFSKQSDIQNLNYGYTDFDNFGSSYFTVFHITRIISWGTITFMYWRHTSTVIVATYFLSL 360
Query: 388 IFLGSFYLVNLILAIVAMSY 407
+ + S+ L N+ILA + S+
Sbjct: 361 LLIISYVLCNIILAELYESF 380
Score = 45.2 bits (102), Expect = 0.018
Identities = 46/176 (26%), Positives = 79/176 (44%), Gaps = 15/176 (8%)
Query: 775 WDCCWLWL-EFQK----YVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKS 829
W W++L EF + Y ++ D + + I I N +++ A+KS
Sbjct: 659 WATLWVFLIEFIQLRLDYFKDILNDIDLVILIVRLITTNYPLFQGKFVTSEEEWIHAIKS 718
Query: 830 GNYLRVFKLAKS---WPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFG-KNY 885
N R+F++ K+ + T+N LI T+ L ++ +FA++G LF K
Sbjct: 719 INVFRIFQVVKNTSFFRTVNHLIIYFYDTICELFYFIVIIVFYCVLFALIGENLFAFKAQ 778
Query: 886 VDYVDRFPD----GDLPRWNFTDFMHSF-MIVFRVLCGEWIESMWDCM-LVGDVSC 935
D+ P+ G PR N+ +F SF + +L +W SM++ M +GD C
Sbjct: 779 FINGDQIPEDKSMGQSPRINYDNFFSSFEATILNILNEQWNVSMYNYMRSIGDYVC 834
Score = 37.1 bits (82), Expect = 4.9
Identities = 19/64 (29%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
Query: 1314 TMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
T R LRP+R + + +++ + L ++IP I + LIF +AI+G+ +F G
Sbjct: 179 TCRIFAMLRPMRILQMITPLKLQFDRLFRSIPKINLSIWRILIFMAFYAIVGLHIFMGDV 238
Query: 1374 -FKC 1376
++C
Sbjct: 239 EYRC 242
>UniRef50_A5DVK1 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 1890
Score = 90.2 bits (214), Expect = 5e-16
Identities = 85/387 (21%), Positives = 171/387 (44%), Gaps = 28/387 (7%)
Query: 1252 LYYMDRIFTVIFFIEMLIKWLALGF----QKYFTNAWCWLDFIIVMVSLINFVAALCGAG 1307
+++ + F ++F +E +IK +A G YF ++W +DF++++ I +A L G
Sbjct: 1491 MFWSEFAFALVFTLEFIIKIVADGILFTPNAYFRSSWNHIDFVVLVSLWIEAIAYLKNDG 1550
Query: 1308 GIQAFKTMRTLRALRPLRAMSRMQGMRVVV-NALVQAIPSIFNVLLVCLIFWLIFAIMGV 1366
+ + +R L+ALR LR ++ + + N ++ I + ++ L F+I G+
Sbjct: 1551 DLS--RIVRGLKALRALRLLTISETAKSNFHNTMIAGFGKILSAAIMSLSLLFPFSIWGL 1608
Query: 1367 QLFAGKYFKCVDMNHTTLS--HEIIPDK-NACTLENYTWENSPMNFDHVGKAYLCLFQVA 1423
+F G+ C+D LS +E + N + + N + F+ A+ LF++
Sbjct: 1609 NIFNGRLGYCLDGESDLLSCFNEFSNEVFNWEIVSPNVYTNPQLEFNKFSSAFATLFEIV 1668
Query: 1424 TFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQ 1483
+ +GW ++ + ++S +G P N ++ L LF+ VII N++
Sbjct: 1669 SLEGWTDLLQNLMNSTGIGTVPETNANPINGVFIVFFNFISTVFILTLFVSVIISNYSRT 1728
Query: 1484 KKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIM 1543
+A +MT+DQ +Y + +P K R + ++V + +
Sbjct: 1729 TGRA------YMTKDQISWYQVKNILVQVRPSK---RKDYESLSVVRKFCYRMTIERHKG 1779
Query: 1544 LFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFS-SECLLKIFALRYHYFVEP---- 1598
+I LN E F + D LN++ I+I++ + L I A+ P
Sbjct: 1780 WYITLNCTLFAHTLALLLECFPSG-DGLNVLRIIIYTVASALFLINAVMLAIAQGPKTFC 1838
Query: 1599 ---WNLFDFVVVMFSILSLVLSDIIEK 1622
WN+F+ V + ++ +++ IE+
Sbjct: 1839 HYRWNIFNLFVSFGAFITTLVAFSIEQ 1865
Score = 68.5 bits (160), Expect = 2e-09
Identities = 54/256 (21%), Positives = 118/256 (46%), Gaps = 21/256 (8%)
Query: 1537 KFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH--- 1593
KF+ + + I +NM Y SE +L + F ++F +E +++ H
Sbjct: 1026 KFEFLFIACIAVNMFVQCFRSYDMSEDTRFILSRFEVAFTIVFMAEIIVRFLVYLPHWKL 1085
Query: 1594 YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRT 1653
+F N D ++ + S++ + + + K + L V ++ R R+V RT
Sbjct: 1086 FFAFKRNWVDLILALGSVI-IAIGPVKRKLGHAYFWLTVFQIL---RFYRVVLATPFTRT 1141
Query: 1654 LLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDV-YNFKTFVQSMILL 1712
L +A ++ A+F++ L F+++F+ +I +F D+V + T I L
Sbjct: 1142 LWLKMAKNIRAIFDLALFYFILLFLVSIILARYFEGTIPPDEFDNVDFPMNTLPAVFIAL 1201
Query: 1713 FQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMY 1772
+ ++++ W V+ + +E S + G +L+++ ++S +I++N++
Sbjct: 1202 YVITSTENWTDVMYSL--QEYAT----------TTSSRSFGSIFLIAWFMLSNMIILNIF 1249
Query: 1773 IAVILENYSQATEDVQ 1788
IAVI N + +E+++
Sbjct: 1250 IAVI-ANTLEVSEEIK 1264
Score = 62.9 bits (146), Expect = 9e-08
Identities = 43/167 (25%), Positives = 76/167 (45%), Gaps = 9/167 (5%)
Query: 126 PFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKV 185
P+ P+ I ++ L I+ + M + +E F ++T E +K+
Sbjct: 1451 PYRPLSESLIVVMFLATIGLVILACYMTPIFRMNNANAKWMFWSEFAFALVFTLEFIIKI 1510
Query: 186 MARGFILQPFTYLRDAWNWLDFVVI------ALAYVTMGIDLGNLAALRTFRVLRALKTV 239
+A G + P Y R +WN +DFVV+ A+AY+ DL + +R + LRAL+ +
Sbjct: 1511 VADGILFTPNAYFRSSWNHIDFVVLVSLWIEAIAYLKNDGDLSRI--VRGLKALRALRLL 1568
Query: 240 AIVPGLKT-IVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVL 285
I K+ +I + I+++ L F++ GL I+ G L
Sbjct: 1569 TISETAKSNFHNTMIAGFGKILSAAIMSLSLLFPFSIWGLNIFNGRL 1615
Score = 61.7 bits (143), Expect = 2e-07
Identities = 59/231 (25%), Positives = 104/231 (45%), Gaps = 24/231 (10%)
Query: 197 YLRDAWNWLDFVVIALAYVTMGIDLG------NLAALRTFRVLRALKTVAIVPGLKTIVG 250
YLR +W+ +DF+ + ++++ + + ++ R+ LR L+ + G TI+
Sbjct: 747 YLRSSWHRIDFLSMVFFWISLLLSINRYDAKHHITLFRSLSCLRILRLCNLTAGTTTILA 806
Query: 251 AVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERF 310
A ++ L DV I F ++G+Q + LT+ CV P+D S T N + +
Sbjct: 807 ACKSAIPQLIDVAIFIACFWLFFGIIGVQSFKSSLTRHCVWTNPDDPS-DIFT--NSDLY 863
Query: 311 CQNETNWYGEGGDY-PLCGNSSGA--GQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSA 367
C + GE Y G SSG G P Y + G NP G SFD +
Sbjct: 864 CGSFIGLDGEKKSYITREGTSSGVVKGFRCPKY-SKRISGDNPYGGTVSFDNILQSLEMV 922
Query: 368 FRLMTQDYWENLYQ-----------LFFVVIIFLGSFYLVNLILAIVAMSY 407
F +M+ + + ++ LFF+ IF+ + +L+N+ A++ S+
Sbjct: 923 FVVMSANTFTDIMYYTMDTDNMAACLFFIGCIFVMTVWLLNIFTAVIVASF 973
Score = 50.0 bits (114), Expect = 6e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 1279 YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVN 1338
Y ++W +DF+ ++ I+ + ++ R+L LR LR + G ++
Sbjct: 747 YLRSSWHRIDFLSMVFFWISLLLSINRYDAKHHITLFRSLSCLRILRLCNLTAGTTTILA 806
Query: 1339 ALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFK-CVDMN 1380
A AIP + +V + FWL F I+GVQ F + CV N
Sbjct: 807 ACKSAIPQLIDVAIFIACFWLFFGIIGVQSFKSSLTRHCVWTN 849
Score = 41.9 bits (94), Expect = 0.17
Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Query: 1590 LRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
L+ Y W+ DF+ ++F +SL+LS I +Y + + R R+LRL
Sbjct: 743 LKRAYLRSSWHRIDFLSMVFFWISLLLS--INRYDAKHHIT-LFRSLSCLRILRLCNLTA 799
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
G T+L A ++P L ++ + + F I G+ F
Sbjct: 800 GTTTILAACKSAIPQLIDVAIFIACFWLFFGIIGVQSF 837
Score = 38.3 bits (85), Expect = 2.1
Identities = 68/285 (23%), Positives = 124/285 (43%), Gaps = 54/285 (18%)
Query: 1540 MIIMLF---IGLNMLTMTLDH-YQQSETFSAVLDYLNMIFIVIFSSECLLKIFA-----L 1590
+I+++F IGL +L + ++ + + + + F ++F+ E ++KI A
Sbjct: 1459 LIVVMFLATIGLVILACYMTPIFRMNNANAKWMFWSEFAFALVFTLEFIIKIVADGILFT 1518
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSP-TLLRVVRVAKVGRVLRLV---K 1646
YF WN DFVV ++SL + I Y + L R+VR K R LRL+ +
Sbjct: 1519 PNAYFRSSWNHIDFVV----LVSLWIEAIA--YLKNDGDLSRIVRGLKALRALRLLTISE 1572
Query: 1647 GAK---------GIRTLLFALAMSLPALFNIC---LLLFLVMFIFAIFGMSFFMHVKDKG 1694
AK G +L A MSL LF L +F + + G S + ++
Sbjct: 1573 TAKSNFHNTMIAGFGKILSAAIMSLSLLFPFSIWGLNIFNGRLGYCLDGESDLLSCFNEF 1632
Query: 1695 GLDDVYN---------------FKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDN 1739
++V+N F F + LF++ + GW +L ++N
Sbjct: 1633 S-NEVFNWEIVSPNVYTNPQLEFNKFSSAFATLFEIVSLEGWTDLLQNLMNSTGIGTVPE 1691
Query: 1740 ERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQAT 1784
+P N G+ +++ + IS + ++ ++++VI+ NYS+ T
Sbjct: 1692 TNANPIN------GV-FIVFFNFISTVFILTLFVSVIISNYSRTT 1729
>UniRef50_A6GA84 Cluster: K+ transporter, Kef-type; n=1; Plesiocystis
pacifica SIR-1|Rep: K+ transporter, Kef-type -
Plesiocystis pacifica SIR-1
Length = 301
Score = 89.8 bits (213), Expect = 7e-16
Identities = 63/235 (26%), Positives = 119/235 (50%), Gaps = 27/235 (11%)
Query: 1562 ETFSAVLDYLNMIFIVIFSSECLLKIFA---LRYHYFVEPWNLFDFVVVMFSILSLVLSD 1618
E F + + I + IF +E ++K+ A + YF++PWN+FDFV+V L +
Sbjct: 42 ERFEHPIHIGDQIILWIFVAEIVVKMLAEGKKPWRYFLDPWNVFDFVIVAACFLPFEGNA 101
Query: 1619 IIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFI 1678
+ T+LR++R+ RVL+LVK ++ L+ AL S+P++ + LLLF++ ++
Sbjct: 102 V--------TVLRLLRLL---RVLKLVKALPKLQILVGALLKSIPSMVYVSLLLFMLFYV 150
Query: 1679 FAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPD 1738
+A+ + F G +D +F+ +M+ LF++ T W V+ IN CD
Sbjct: 151 YAVAAVFLF-------GTNDPLHFENLEIAMLSLFRVVTLEDWTDVM--YINMYGCDRYG 201
Query: 1739 NERGSPGNC----GSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQE 1789
S C +G + +S+++ +I++N++I VI+ +A + +
Sbjct: 202 YSADSVVQCVTPKAQPLLGALFFVSFVLTGTMIILNLFIGVIMSGMDEAQAEAAD 256
Score = 68.1 bits (159), Expect = 2e-09
Identities = 45/160 (28%), Positives = 86/160 (53%), Gaps = 13/160 (8%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDV-HLPHRPILQDILYYMDRIFTVIFFIEMLIKW 1271
K+ + +F+T++ +ILL+ + + +E L R + ++ D+I IF E+++K
Sbjct: 10 KIADAAWFQTSITVVILLAGVLVGIETYPALVER--FEHPIHIGDQIILWIFVAEIVVKM 67
Query: 1272 LALGFQ--KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSR 1329
LA G + +YF + W DF+IV + F A +R LR LR L+ +
Sbjct: 68 LAEGKKPWRYFLDPWNVFDFVIVAACFLPFEG--------NAVTVLRLLRLLRVLKLVKA 119
Query: 1330 MQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
+ ++++V AL+++IPS+ V L+ + + ++A+ V LF
Sbjct: 120 LPKLQILVGALLKSIPSMVYVSLLLFMLFYVYAVAAVFLF 159
Score = 62.1 bits (144), Expect = 1e-07
Identities = 36/111 (32%), Positives = 62/111 (55%), Gaps = 6/111 (5%)
Query: 172 IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN-LAALRTF 230
I I+ E VK++A G +P+ Y D WN DFV++A ++ GN + LR
Sbjct: 54 IILWIFVAEIVVKMLAEG--KKPWRYFLDPWNVFDFVIVAACFLPFE---GNAVTVLRLL 108
Query: 231 RVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
R+LR LK V +P L+ +VGA+++S+ ++ V +L V+A+ + ++
Sbjct: 109 RLLRVLKLVKALPKLQILVGALLKSIPSMVYVSLLLFMLFYVYAVAAVFLF 159
Score = 38.3 bits (85), Expect = 2.1
Identities = 16/52 (30%), Positives = 34/52 (65%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKN 884
LRV KL K+ P L +L+ + +++ ++ ++ +L ++ +++AV + LFG N
Sbjct: 111 LRVLKLVKALPKLQILVGALLKSIPSMVYVSLLLFMLFYVYAVAAVFLFGTN 162
>UniRef50_Q9U6N6 Cluster: Calcium channel alpha-1 subunit; n=2;
Bilateria|Rep: Calcium channel alpha-1 subunit -
Bdelloura candida (Horseshoe crab flatworm)
Length = 311
Score = 89.4 bits (212), Expect = 9e-16
Identities = 47/159 (29%), Positives = 89/159 (55%), Gaps = 2/159 (1%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+RL LI+ +F V+ ++LL+++ +A+E + P L LYY D +F +F +E
Sbjct: 155 MRLVVRHLIKTEFFYWLVVCIVLLNTICVAMEHYNQPR--FLNVFLYYTDFVFLTMFLME 212
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
ML+K+ LGF++YF + + DFI+V++S + + F +R +R LR L+
Sbjct: 213 MLLKFFGLGFKEYFRSKFNVFDFIVVLLSAFEVIFQMFSKENSFGFSALRWVRLLRLLKL 272
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMG 1365
+R +V +L+ ++ SI ++L++ +F I ++G
Sbjct: 273 TRYWPSLRNLVFSLLSSVRSILSLLMLLGLFIFILTLLG 311
Score = 82.6 bits (195), Expect = 1e-13
Identities = 44/157 (28%), Positives = 86/157 (54%), Gaps = 4/157 (2%)
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKI 1587
+V ++ + F +++ + LN + + ++HY Q + L Y + +F+ +F E LLK
Sbjct: 158 VVRHLIKTEFFYWLVVCIVLLNTICVAMEHYNQPRFLNVFLYYTDFVFLTMFLMEMLLKF 217
Query: 1588 FALRY-HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVK 1646
F L + YF +N+FDF+VV+ S ++ ++ + LR VR+ R+L+L +
Sbjct: 218 FGLGFKEYFRSKFNVFDFIVVLLSAFEVIFQMFSKENSFGFSALRWVRLL---RLLKLTR 274
Query: 1647 GAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFG 1683
+R L+F+L S+ ++ ++ +LL L +FI + G
Sbjct: 275 YWPSLRNLVFSLLSSVRSILSLLMLLGLFIFILTLLG 311
Score = 46.4 bits (105), Expect = 0.008
Identities = 37/161 (22%), Positives = 75/161 (46%), Gaps = 17/161 (10%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVN--CILMIMPTTPTVES-----TEVIFTGIYTFESA 182
+R V +++ F ++ +L+N C+ M P + T+ +F ++ E
Sbjct: 155 MRLVVRHLIKTEFFYWLVVCIVLLNTICVAMEHYNQPRFLNVFLYYTDFVFLTMFLMEML 214
Query: 183 VKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGN------LAALRTFRVLRAL 236
+K GF Y R +N DF+V+ L+ + + + +ALR R+LR L
Sbjct: 215 LKFFGLGFK----EYFRSKFNVFDFIVVLLSAFEVIFQMFSKENSFGFSALRWVRLLRLL 270
Query: 237 KTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMG 277
K P L+ +V +++ SV+++ +++L + + L+G
Sbjct: 271 KLTRYWPSLRNLVFSLLSSVRSILSLLMLLGLFIFILTLLG 311
>UniRef50_Q16MR6 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 382
Score = 89.4 bits (212), Expect = 9e-16
Identities = 41/79 (51%), Positives = 55/79 (69%), Gaps = 12/79 (15%)
Query: 340 YVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQL-----------FFVVII 388
Y CL G NPN+GYT+FD F W+ L+ F+L+T DYWEN+Y + FF V++
Sbjct: 102 YTCLC-VGENPNHGYTNFDNFMWSMLTTFQLITLDYWENVYNMVLATCGPMSVSFFTVVV 160
Query: 389 FLGSFYLVNLILAIVAMSY 407
F GSFYL+NL+LA+VA+SY
Sbjct: 161 FFGSFYLINLMLAVVALSY 179
>UniRef50_Q86XQ3 Cluster: Cation channel sperm-associated protein 3
(CatSper3) (One-repeat calcium channel-like protein)
(Ca(v)-like protein); n=16; Theria|Rep: Cation channel
sperm-associated protein 3 (CatSper3) (One-repeat calcium
channel-like protein) (Ca(v)-like protein) - Homo sapiens
(Human)
Length = 398
Score = 85.8 bits (203), Expect = 1e-14
Identities = 56/208 (26%), Positives = 104/208 (50%), Gaps = 8/208 (3%)
Query: 1526 QAIVFEIVTDKKFDMIIMLFIGLNMLTMTL-DHYQQSETFSAVLDYLNMIFIVIFSSECL 1584
+A V ++ + F +I++ + N M L Y +L++ + F+ I +SE
Sbjct: 40 RAFVKRVIMSRFFKIIMISTVTSNAFFMALWTSYDIRYRLFRLLEFSEIFFVSICTSELS 99
Query: 1585 LKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRL 1644
+K++ +Y+ +NL D ++++ L L ++ K F T L + + R+L+L
Sbjct: 100 MKVYVDPINYWKNGYNLLDVIIIIVMFLPYALRQLMGKQF---TYLYIADGMQSLRILKL 156
Query: 1645 VKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKT 1704
+ ++GIRTL+ A+ ++ + ++ LLLFL+M+IFAI G F D G D N+
Sbjct: 157 IGYSQGIRTLITAVGQTVYTVASVLLLLFLLMYIFAILGFCLF-GSPDNGDHD---NWGN 212
Query: 1705 FVQSMILLFQMSTSAGWDGVLDGIINEE 1732
+ LF ++T GW + + N E
Sbjct: 213 LAAAFFTLFSLATVDGWTDLQKQLDNRE 240
Score = 50.0 bits (114), Expect = 6e-04
Identities = 34/126 (26%), Positives = 63/126 (50%), Gaps = 6/126 (4%)
Query: 1250 DILYYMDRI--FTVIFFIEMLIKWLALGFQ----KYFTNAWCWLDFIIVMVSLINFVAAL 1303
DI Y + R+ F+ IFF+ + L++ Y+ N + LD II++V + +
Sbjct: 74 DIRYRLFRLLEFSEIFFVSICTSELSMKVYVDPINYWKNGYNLLDVIIIIVMFLPYALRQ 133
Query: 1304 CGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAI 1363
+++LR L+ + QG+R ++ A+ Q + ++ +VLL+ + IFAI
Sbjct: 134 LMGKQFTYLYIADGMQSLRILKLIGYSQGIRTLITAVGQTVYTVASVLLLLFLLMYIFAI 193
Query: 1364 MGVQLF 1369
+G LF
Sbjct: 194 LGFCLF 199
Score = 36.7 bits (81), Expect = 6.4
Identities = 16/50 (32%), Positives = 32/50 (64%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFG 882
LR+ KL + LI+ +G+T+ + ++ +L ++++IFA++G LFG
Sbjct: 151 LRILKLIGYSQGIRTLITAVGQTVYTVASVLLLLFLLMYIFAILGFCLFG 200
>UniRef50_Q9KCR8 Cluster: BH1501 protein; n=4; Bacillaceae|Rep: BH1501
protein - Bacillus halodurans
Length = 274
Score = 85.4 bits (202), Expect = 1e-14
Identities = 58/182 (31%), Positives = 100/182 (54%), Gaps = 19/182 (10%)
Query: 1210 KTFKLIENTYFETAVITMILLSSLALALED---VHLPHRPILQDILYYMDRIFTVIFFIE 1266
K K++ + F VI +IL ++L + +E ++ H+ + Y +D + IF IE
Sbjct: 15 KMQKIVNHRAFTFTVIALILFNALIVGIETYPRIYADHKWLF----YRIDLVLLWIFTIE 70
Query: 1267 MLIKWLALGFQK-YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLR 1325
+ +++LA + +F ++W W DF+IV I G Q +R LR LR LR
Sbjct: 71 IAMRFLASNPKSAFFRSSWNWFDFLIVAAGHI--------FAGAQFVTVLRILRVLRVLR 122
Query: 1326 AMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF---AGKYFKCVDMNHT 1382
A+S + +R +V+ALV IP++ N+L++ IF+ IFA++G LF + +YF + ++
Sbjct: 123 AISVVPSLRRLVDALVMTIPALGNILILMSIFFYIFAVIGTMLFQHVSPEYFGNLQLSLL 182
Query: 1383 TL 1384
TL
Sbjct: 183 TL 184
Score = 82.2 bits (194), Expect = 1e-13
Identities = 68/268 (25%), Positives = 124/268 (46%), Gaps = 40/268 (14%)
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDY-LNMIFIVIFSSECLLKIFA 1589
+IV + F ++ I N L + ++ Y + L Y ++++ + IF+ E ++ A
Sbjct: 18 KIVNHRAFTFTVIALILFNALIVGIETYPRIYADHKWLFYRIDLVLLWIFTIEIAMRFLA 77
Query: 1590 L--RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKG 1647
+ +F WN FDF++V + F + V+R+ +V RVLR +
Sbjct: 78 SNPKSAFFRSSWNWFDFLIVAAGHI-----------FAGAQFVTVLRILRVLRVLRAISV 126
Query: 1648 AKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQ 1707
+R L+ AL M++PAL NI +L+ + +IFA+ G F HV + F
Sbjct: 127 VPSLRRLVDALVMTIPALGNILILMSIFFYIFAVIGTMLFQHVSPE-------YFGNLQL 179
Query: 1708 SMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLI 1767
S++ LFQ+ T W G++ ++P Y +S+++I I
Sbjct: 180 SLLTLFQVVTLESW---ASGVMRPIFAEVP--------------WSWLYFVSFVLIGTFI 222
Query: 1768 VINMYIAVILENYSQA--TEDVQEGLTD 1793
+ N++I VI+ N +A T++ ++G D
Sbjct: 223 IFNLFIGVIVNNVEKAELTDNEEDGEAD 250
Score = 78.6 bits (185), Expect = 2e-12
Identities = 41/156 (26%), Positives = 83/156 (53%), Gaps = 13/156 (8%)
Query: 137 ILVHPLFSLFIITTILVNCILMIMPTTPTVEST--------EVIFTGIYTFESAVKVMAR 188
I+ H F+ +I IL N +++ + T P + + +++ I+T E A++ +A
Sbjct: 19 IVNHRAFTFTVIALILFNALIVGIETYPRIYADHKWLFYRIDLVLLWIFTIEIAMRFLAS 78
Query: 189 GFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTI 248
+ R +WNW DF+++A ++ G + LR RVLR L+ +++VP L+ +
Sbjct: 79 N---PKSAFFRSSWNWFDFLIVAAGHIFAGAQF--VTVLRILRVLRVLRAISVVPSLRRL 133
Query: 249 VGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
V A++ ++ L +++IL +FA++G ++ V
Sbjct: 134 VDALVMTIPALGNILILMSIFFYIFAVIGTMLFQHV 169
Score = 40.7 bits (91), Expect = 0.40
Identities = 23/72 (31%), Positives = 35/72 (48%)
Query: 810 LFMALDHHNMDKDMDKALKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCII 869
L +A H L+ LRV + P+L L+ + T+ ALGN+ ++ I
Sbjct: 95 LIVAAGHIFAGAQFVTVLRILRVLRVLRAISVVPSLRRLVDALVMTIPALGNILILMSIF 154
Query: 870 IFIFAVMGMQLF 881
+IFAV+G LF
Sbjct: 155 FYIFAVIGTMLF 166
>UniRef50_O73706 Cluster: Voltage-dependent N-type calcium channel
subunit alpha-1B; n=42; Euteleostomi|Rep:
Voltage-dependent N-type calcium channel subunit alpha-1B
- Gallus gallus (Chicken)
Length = 159
Score = 84.6 bits (200), Expect = 2e-14
Identities = 46/155 (29%), Positives = 88/155 (56%), Gaps = 8/155 (5%)
Query: 1624 FVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFG 1683
F++ + LR+ R A R+++L++ IR LL+ S AL +CLL+ ++ FI+AI G
Sbjct: 11 FINLSFLRLFRAA---RLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIG 67
Query: 1684 MSFFMHV--KDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNER 1741
M F ++ D+ ++ NF+TF+Q+++LLF+ +T W ++ ++ CD
Sbjct: 68 MQVFGNIALNDETSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNRACDPLSGL- 126
Query: 1742 GSPGNCGSATIGITYLLSYLVISFLIVINMYIAVI 1776
+ CGS Y +S++ + +++N+++AVI
Sbjct: 127 -TKNECGS-DFAYFYFVSFIFLCSFLMLNLFVAVI 159
Score = 47.2 bits (107), Expect = 0.005
Identities = 28/97 (28%), Positives = 53/97 (54%), Gaps = 7/97 (7%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFP 893
R+ KL + T+ +L+ ++ AL + ++ ++ FI+A++GMQ+FG ++
Sbjct: 24 RLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALN-----D 78
Query: 894 DGDLPRW-NFTDFMHSFMIVFRVLCGE-WIESMWDCM 928
+ + R NF F+ + M++FR GE W E M C+
Sbjct: 79 ETSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCL 115
>UniRef50_Q4RWE1 Cluster: Chromosome 2 SCAF14990, whole genome shotgun
sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 2
SCAF14990, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1367
Score = 84.2 bits (199), Expect = 3e-14
Identities = 85/353 (24%), Positives = 166/353 (47%), Gaps = 23/353 (6%)
Query: 1536 KKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR-YHY 1594
+ F ++ +FI L++L + + + TF L ++++F IF E +K+ A+ Y
Sbjct: 857 RDFGGVMDIFIYLSVLLSVKWNVKDNVTFP--LATMSVVFTFIFVLEVTMKLIAMSPAGY 914
Query: 1595 FVEPWNLFDFVVVMFSILSLVLS-DIIEKY-FVSPTLLRVVRVAKV-GRVLRLVKGAKGI 1651
+ N +D +V ++ +VL ++ Y ++ T + V R + G+ + L
Sbjct: 915 WQSRRNRYDLLVTSLGVIWIVLHFSLLNAYTYMMGTCVIVFRFFTICGKHVTL------- 967
Query: 1652 RTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMIL 1711
+ LL + +S+ F I + +FL++ +A G+ F VK ++ NF T +++ +
Sbjct: 968 KMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKFGENINRHANFSTAGKAIAV 1027
Query: 1712 LFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINM 1771
LF++ T W+ ++ + + PD R +CG+ + Y S+ VI I++N+
Sbjct: 1028 LFRIVTGEDWNKIMHDCMVQAPFCTPDKHRYWETDCGNYAGALIYFCSFYVIIAYIMLNL 1087
Query: 1772 YIAVILENYS--QATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVLEPP 1829
+A+I+EN+S +TE+ Q L+ +D + IW D I ++ L +L
Sbjct: 1088 LVAIIVENFSLFYSTEEDQL-LSYNDLRHFQIIWNMVDDKREGVIPTSRVKFLLRLLRGR 1146
Query: 1830 LQIHKPN-----KYKIISMDIPICRGDMMFCVDILDALT-KDFFARKGNPIEE 1876
L++ K+ M+ GD+ F D+L L+ + RK +EE
Sbjct: 1147 LEVDLDKDKLLFKHMCYEMERLHSGGDVTF-HDVLSMLSYRSVDIRKSLQLEE 1198
Score = 51.2 bits (117), Expect = 3e-04
Identities = 104/456 (22%), Positives = 187/456 (41%), Gaps = 67/456 (14%)
Query: 1210 KTFKLIENTYFETAVI-TMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEML 1268
KTF+ + T + T+++ A + +H+ I D Y DR + V + +
Sbjct: 72 KTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHI-RGMIKGDNSYVKDR-WCVFDGLMVF 129
Query: 1269 IKWLALGFQKYFT-------NAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRAL 1321
W++L Q Y T N C II + + +A + + ++ +R RAL
Sbjct: 130 FIWVSLVLQVYVTFTDVVLINHICLHHSIIFRLFQVFEIATIVDQ--MSPWRMLRIPRAL 187
Query: 1322 RPLRAMS---RMQGMRV-VVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCV 1377
+RA R + R + N L ++ I++V + L F L++ I+GVQ+F F CV
Sbjct: 188 IMIRAFRIYFRFELPRSRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGTFNFHCV 247
Query: 1378 DMNHTTLSHEI------IPDKNACTL-ENYTW-----------------ENSPMNFDHVG 1413
+ T+S E+ IPD + E Y E F+ +G
Sbjct: 248 --TNETMSGEVTWNSLAIPDTHCSPDGEGYQCPSGFKCVDLGHLGLSRQELGYSGFNELG 305
Query: 1414 KAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFI 1473
+ +++ A+ +GW+ +M AIDS R Y Y N+FI
Sbjct: 306 TSIFTVYEAASQEGWVFLMYRAIDSFPRWRS---------YFYFITLIFFLAWLVKNVFI 356
Query: 1474 GVIIDNFNE---QKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIV- 1529
VII+ F E Q ++ GS + + ++ G + + +P R A +
Sbjct: 357 AVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPHGRAPACLQ 416
Query: 1530 -------FEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLD--YL-NMIFIVIF 1579
+++ F M I+ + ++++ + +Y + E D YL + F V+F
Sbjct: 417 IWTCDGFKQLMRSSWFHMFILSMVAVDVI-VAASNYYKGENHRRHYDEFYLAEVAFTVLF 475
Query: 1580 SSECLLKIFALRY-HYFVEPWNLFDFVVVMFSILSL 1614
E LLKI+ L + Y + F+ ++V+ + L +
Sbjct: 476 DLEALLKIWCLGFTGYISSSLHKFESLLVVGTTLHI 511
>UniRef50_UPI0000E23FE5 Cluster: PREDICTED: similar to calcium channel
alpha-1-H subunit; n=1; Pan troglodytes|Rep: PREDICTED:
similar to calcium channel alpha-1-H subunit - Pan
troglodytes
Length = 1640
Score = 83.4 bits (197), Expect = 6e-14
Identities = 46/161 (28%), Positives = 80/161 (49%), Gaps = 8/161 (4%)
Query: 1367 QLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFK 1426
QLF GK++ C + +S K C +Y W NFD++G+A + LF +++
Sbjct: 1300 QLFKGKFYYCEGPDTRNIS-----TKAQCRAAHYRWVRRKYNFDNLGQALMSLFVLSSKD 1354
Query: 1427 GWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKK 1486
GW+ IM D +D+ V +QP++ N +M LY LN+F+GV+++NF+ K +
Sbjct: 1355 GWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFH--KCR 1412
Query: 1487 AGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQA 1527
E ++K+ ++ S P + +P PQ+
Sbjct: 1413 QHQEAEEARRREEKRLRRLERRRRSTSPAQ-VPALSRMPQS 1452
Score = 61.3 bits (142), Expect = 3e-07
Identities = 25/56 (44%), Positives = 41/56 (73%)
Query: 1313 KTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQL 1368
+ +R LR LRPLR +SR G+++VV L+ ++ I N++L+C F++IF I+GVQ+
Sbjct: 1184 RVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQV 1239
Score = 48.8 bits (111), Expect = 0.001
Identities = 39/163 (23%), Positives = 77/163 (47%), Gaps = 30/163 (18%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVE--STEVIFTGIY 177
AL++ P N R ++ H +F ++ I +NC+ + + P ++ STE +F +
Sbjct: 1105 ALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALER-PDIDPGSTERVFLSVS 1163
Query: 178 TFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALK 237
N++ F I +A + + I LG L LR R LR L+
Sbjct: 1164 -------------------------NYI-FTAIFVAEMMVKI-LGVLRVLRLLRTLRPLR 1196
Query: 238 TVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQI 280
++ PGLK +V +I S++ + +++++ +F ++G+Q+
Sbjct: 1197 VISRAPGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQV 1239
Score = 40.7 bits (91), Expect = 0.40
Identities = 21/86 (24%), Positives = 44/86 (51%), Gaps = 7/86 (8%)
Query: 1700 YNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLS 1759
YNF Q+++ LF +S+ GW ++ ++ D + +P + Y +S
Sbjct: 1335 YNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWM-------LLYFIS 1387
Query: 1760 YLVISFLIVINMYIAVILENYSQATE 1785
+L+I V+NM++ V++EN+ + +
Sbjct: 1388 FLLIVSFFVLNMFVGVVVENFHKCRQ 1413
Score = 39.9 bits (89), Expect = 0.69
Identities = 20/62 (32%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTLDH--YQQSETFSAVLDYLNMIFIVIFSSECLLKIF 1588
+++T K FD ++++FI LN +T+ L+ T L N IF IF +E ++KI
Sbjct: 1121 KVITHKMFDHVVLVFIFLNCVTIALERPDIDPGSTERVFLSVSNYIFTAIFVAEMMVKIL 1180
Query: 1589 AL 1590
+
Sbjct: 1181 GV 1182
Score = 39.5 bits (88), Expect = 0.91
Identities = 18/52 (34%), Positives = 31/52 (59%)
Query: 222 GNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVF 273
G L+ LRTFR+LR LK V +P L+ + +++++ N+ L M + +F
Sbjct: 730 GGLSVLRTFRLLRVLKLVRFLPALRRQLVVLVKTMDNVATFCTLLMLFIFIF 781
>UniRef50_Q96P56-3 Cluster: Isoform 3 of Q96P56 ; n=4; Mammalia|Rep:
Isoform 3 of Q96P56 - Homo sapiens (Human)
Length = 414
Score = 83.0 bits (196), Expect = 7e-14
Identities = 54/171 (31%), Positives = 95/171 (55%), Gaps = 7/171 (4%)
Query: 1201 WQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFT 1260
W GW L FK F + T+IL+ + L LE + P L+ L
Sbjct: 100 WAGW-VLECPLFKNF--IIFLVFLNTIILMVEIEL-LESTNTKLWP-LKLTLEVAAWFIL 154
Query: 1261 VIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAF-KTMRTLR 1319
+IF +E+L+KWL+ F ++ +AW DF++ M+SL+ V L G G + + +R R
Sbjct: 155 LIFILEILLKWLS-NFSVFWKSAWNVFDFVVTMLSLLPEVVVLVGVTGQSVWLQLLRICR 213
Query: 1320 ALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
LR L+ +++ + +++++ LV+A+ S+ +L++ LIF+ IFA+ GV +F+
Sbjct: 214 VLRSLKLLAQFRQIQIIILVLVRALKSMTFLLMLLLIFFYIFAVTGVYVFS 264
Score = 68.9 bits (161), Expect = 1e-09
Identities = 59/283 (20%), Positives = 129/283 (45%), Gaps = 23/283 (8%)
Query: 1529 VFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSET----FSAVLDYLNMIFIVIFSSECL 1584
V E K F +I ++F+ +L + ++ + + T L+ ++IF E L
Sbjct: 104 VLECPLFKNF-IIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEIL 162
Query: 1585 LKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRL 1644
LK + ++ WN+FDFVV M S+L V+ ++ L+++R+ +V R L+L
Sbjct: 163 LKWLSNFSVFWKSAWNVFDFVVTMLSLLPEVV--VLVGVTGQSVWLQLLRICRVLRSLKL 220
Query: 1645 VKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYN--F 1702
+ + I+ ++ L +L ++ + +LL + +IFA+ G+ F D Y+ F
Sbjct: 221 LAQFRQIQIIILVLVRALKSMTFLLMLLLIFFYIFAVTGVYVFSEYTRSPRQDLEYHVFF 280
Query: 1703 KTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLV 1762
S++ +F + T W +L + E S Y + +L+
Sbjct: 281 SDLPNSLVTVFILFTLDHWYALLQDVWKVPEV--------------SRIFSSIYFILWLL 326
Query: 1763 ISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQR 1805
+ +I ++ +A+++ N+ +++ E + + + ++++R
Sbjct: 327 LGSIIFRSIIVAMMVTNFQNIRKELNEEMARREVQLKADMFKR 369
Score = 52.4 bits (120), Expect = 1e-04
Identities = 47/169 (27%), Positives = 85/169 (50%), Gaps = 17/169 (10%)
Query: 129 PIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEV-IFTGIYTFESAVKVMA 187
P+ A ++L PLF FII + +N I+ +M +EST ++ T E A +
Sbjct: 96 PLSLWAGWVLECPLFKNFIIFLVFLNTII-LMVEIELLESTNTKLWPLKLTLEVAAWFIL 154
Query: 188 RGFILQPF--------TYLRDAWNWLDFVVIALA-----YVTMGIDLGN--LAALRTFRV 232
FIL+ + + AWN DFVV L+ V +G+ + L LR RV
Sbjct: 155 LIFILEILLKWLSNFSVFWKSAWNVFDFVVTMLSLLPEVVVLVGVTGQSVWLQLLRICRV 214
Query: 233 LRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
LR+LK +A ++ I+ ++ ++K++ +++L + +FA+ G+ ++
Sbjct: 215 LRSLKLLAQFRQIQIIILVLVRALKSMTFLLMLLLIFFYIFAVTGVYVF 263
>UniRef50_Q96P56 Cluster: Cation channel sperm-associated protein 2;
n=14; Eutheria|Rep: Cation channel sperm-associated
protein 2 - Homo sapiens (Human)
Length = 530
Score = 83.0 bits (196), Expect = 7e-14
Identities = 54/171 (31%), Positives = 95/171 (55%), Gaps = 7/171 (4%)
Query: 1201 WQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFT 1260
W GW L FK F + T+IL+ + L LE + P L+ L
Sbjct: 100 WAGW-VLECPLFKNF--IIFLVFLNTIILMVEIEL-LESTNTKLWP-LKLTLEVAAWFIL 154
Query: 1261 VIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAF-KTMRTLR 1319
+IF +E+L+KWL+ F ++ +AW DF++ M+SL+ V L G G + + +R R
Sbjct: 155 LIFILEILLKWLS-NFSVFWKSAWNVFDFVVTMLSLLPEVVVLVGVTGQSVWLQLLRICR 213
Query: 1320 ALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
LR L+ +++ + +++++ LV+A+ S+ +L++ LIF+ IFA+ GV +F+
Sbjct: 214 VLRSLKLLAQFRQIQIIILVLVRALKSMTFLLMLLLIFFYIFAVTGVYVFS 264
Score = 68.9 bits (161), Expect = 1e-09
Identities = 59/283 (20%), Positives = 129/283 (45%), Gaps = 23/283 (8%)
Query: 1529 VFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSET----FSAVLDYLNMIFIVIFSSECL 1584
V E K F +I ++F+ +L + ++ + + T L+ ++IF E L
Sbjct: 104 VLECPLFKNF-IIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEIL 162
Query: 1585 LKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRL 1644
LK + ++ WN+FDFVV M S+L V+ ++ L+++R+ +V R L+L
Sbjct: 163 LKWLSNFSVFWKSAWNVFDFVVTMLSLLPEVV--VLVGVTGQSVWLQLLRICRVLRSLKL 220
Query: 1645 VKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYN--F 1702
+ + I+ ++ L +L ++ + +LL + +IFA+ G+ F D Y+ F
Sbjct: 221 LAQFRQIQIIILVLVRALKSMTFLLMLLLIFFYIFAVTGVYVFSEYTRSPRQDLEYHVFF 280
Query: 1703 KTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLV 1762
S++ +F + T W +L + E S Y + +L+
Sbjct: 281 SDLPNSLVTVFILFTLDHWYALLQDVWKVPEV--------------SRIFSSIYFILWLL 326
Query: 1763 ISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQR 1805
+ +I ++ +A+++ N+ +++ E + + + ++++R
Sbjct: 327 LGSIIFRSIIVAMMVTNFQNIRKELNEEMARREVQLKADMFKR 369
Score = 52.4 bits (120), Expect = 1e-04
Identities = 47/169 (27%), Positives = 85/169 (50%), Gaps = 17/169 (10%)
Query: 129 PIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEV-IFTGIYTFESAVKVMA 187
P+ A ++L PLF FII + +N I+ +M +EST ++ T E A +
Sbjct: 96 PLSLWAGWVLECPLFKNFIIFLVFLNTII-LMVEIELLESTNTKLWPLKLTLEVAAWFIL 154
Query: 188 RGFILQPF--------TYLRDAWNWLDFVVIALA-----YVTMGIDLGN--LAALRTFRV 232
FIL+ + + AWN DFVV L+ V +G+ + L LR RV
Sbjct: 155 LIFILEILLKWLSNFSVFWKSAWNVFDFVVTMLSLLPEVVVLVGVTGQSVWLQLLRICRV 214
Query: 233 LRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
LR+LK +A ++ I+ ++ ++K++ +++L + +FA+ G+ ++
Sbjct: 215 LRSLKLLAQFRQIQIIILVLVRALKSMTFLLMLLLIFFYIFAVTGVYVF 263
>UniRef50_Q91ZR5 Cluster: Cation channel sperm-associated protein 1;
n=12; Murinae|Rep: Cation channel sperm-associated
protein 1 - Mus musculus (Mouse)
Length = 686
Score = 83.0 bits (196), Expect = 7e-14
Identities = 68/267 (25%), Positives = 121/267 (45%), Gaps = 33/267 (12%)
Query: 1526 QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSA-VLDYLNMIFIVIFSSECL 1584
Q ++ + F+ I + + LN + + + + E L+ IF+ I+ E +
Sbjct: 341 QQMILSLTQSLGFETFIFIVVCLNTVILVAQTFTELEIRGEWYFMVLDSIFLSIYVLEAV 400
Query: 1585 LKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDI--IEKYFVSPTLLRVVRVAKVGRVL 1642
LK+ AL YF +PWN DF +++ ++L VL I + F + +L R+++V K R L
Sbjct: 401 LKLIALGLEYFYDPWNNLDFFIMVMAVLDFVLLQINSLSYSFYNHSLFRILKVFKSMRAL 460
Query: 1643 RLVKGAKGIRTLLF------ALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGL 1696
R ++ + + L L+ SLP++ I L+F +F+F++ + F
Sbjct: 461 RAIRVLRRLSILTSLHEVAGTLSGSLPSITAILTLMFTCLFLFSVVLRALFQD------- 513
Query: 1697 DDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITY 1756
D F+ ++ LF M T W L I N + A I
Sbjct: 514 SDPKRFQNIFTTLFTLFTMLTLDDWS--LIYIDNRAQ---------------GAWYIIPI 556
Query: 1757 LLSYLVISFLIVINMYIAVILENYSQA 1783
L+ Y+VI + I +N+ IAV+++N+ A
Sbjct: 557 LMIYIVIQYFIFLNLVIAVLVDNFQMA 583
Score = 63.7 bits (148), Expect = 5e-08
Identities = 47/175 (26%), Positives = 89/175 (50%), Gaps = 15/175 (8%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALED-VHLPHRPILQDILYYMDRIFTVIFFI 1265
L+ L ++ FET + ++ L+++ L + L R + +D IF I+ +
Sbjct: 340 LQQMILSLTQSLGFETFIFIVVCLNTVILVAQTFTELEIRG--EWYFMVLDSIFLSIYVL 397
Query: 1266 EMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGG-----------IQAFKT 1314
E ++K +ALG + YF + W LDF I+++++++FV + ++ FK+
Sbjct: 398 EAVLKLIALGLE-YFYDPWNNLDFFIMVMAVLDFVLLQINSLSYSFYNHSLFRILKVFKS 456
Query: 1315 MRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
MR LRA+R LR +S + + V L ++PSI +L + +F+++ LF
Sbjct: 457 MRALRAIRVLRRLSILTSLHEVAGTLSGSLPSITAILTLMFTCLFLFSVVLRALF 511
Score = 42.3 bits (95), Expect = 0.13
Identities = 36/159 (22%), Positives = 72/159 (45%), Gaps = 30/159 (18%)
Query: 143 FSLFIITTILVNCILMIMPTTPTVEST--------EVIFTGIYTFESAVKVMARGFILQP 194
F FI + +N ++++ T +E + IF IY E+ +K++A G
Sbjct: 353 FETFIFIVVCLNTVILVAQTFTELEIRGEWYFMVLDSIFLSIYVLEAVLKLIALGL---- 408
Query: 195 FTYLRDAWNWLDFVVIALA---YVTMGID--------------LGNLAALRTFRVLRALK 237
Y D WN LDF ++ +A +V + I+ L ++R R +R L+
Sbjct: 409 -EYFYDPWNNLDFFIMVMAVLDFVLLQINSLSYSFYNHSLFRILKVFKSMRALRAIRVLR 467
Query: 238 TVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALM 276
++I+ L + G + S+ ++ ++ L L +F+++
Sbjct: 468 RLSILTSLHEVAGTLSGSLPSITAILTLMFTCLFLFSVV 506
>UniRef50_A7SLD2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 741
Score = 82.6 bits (195), Expect = 1e-13
Identities = 64/271 (23%), Positives = 130/271 (47%), Gaps = 21/271 (7%)
Query: 1524 RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSEC 1583
R +A + + F +IM+ I LNM+ M L+H+ Q + + L+ N++F+ IF E
Sbjct: 471 RFRAFCRRMAESRHFSRLIMIAILLNMICMGLEHHNQPQALTVTLEKTNIVFVTIFVLEM 530
Query: 1584 LLKIFALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVL 1642
++ + + Y + N+FD VV+ S+ L+L E + ++ R + R+L
Sbjct: 531 IINVISFGIMGYLSQLQNIFDGFVVVLSVTELLL----ENGYARLSVFRSI------RLL 580
Query: 1643 RLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMS-----FFMHVKDKGGLD 1697
R+ K + +R L + ++ ++ LLFL MF FAI GM+ F+ + +
Sbjct: 581 RIFKLVRPVRYQLLVVIRTMTSVVTFFGLLFLFMFAFAILGMNLFGGEFYFPNAENISVP 640
Query: 1698 DVYNFKTFVQSMILLFQMSTSA--GWDGVLDGIINEEECDLPD---NERGSPGNCGSATI 1752
NF +F+ +M+ +FQ+ + G D + I L N+ G ++
Sbjct: 641 ARTNFDSFLWAMVTVFQVRRGSCHGDDVPYEKKIIAMVTILTQENWNQVMFKGMRATSYW 700
Query: 1753 GITYLLSYLVISFLIVINMYIAVILENYSQA 1783
Y ++ + + + ++ N+ +A+++E ++ +
Sbjct: 701 AALYFIALMTVGYYVLFNLLVAILVEGFTSS 731
Score = 82.2 bits (194), Expect = 1e-13
Identities = 48/158 (30%), Positives = 82/158 (51%), Gaps = 12/158 (7%)
Query: 143 FSLFIITTILVNCILMIM--PTTP--------TVESTEVIFTGIYTFESAVKVMARGFIL 192
F + ILVNCI + M P +E E G + E VK++A G +
Sbjct: 5 FERISMVIILVNCITLAMYDPLDKRCEKVRCNVLEKFEFFIFGFFLLEMVVKMVAMG-VF 63
Query: 193 QPFTYLRDAWNWLDFVVIALAYVTMGIDLGN-LAALRTFRVLRALKTVAIVPGLKTIVGA 251
YL+D WN LDFV+I + + + + L +R FRVLR L+ + VP ++ +V
Sbjct: 64 GSHGYLQDTWNKLDFVIIVMGVIEKSLQGSDYLTIIRAFRVLRPLRAINKVPSIRILVTL 123
Query: 252 VIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKC 289
+++++ L +V++L+ VF ++G+Q++ G L +C
Sbjct: 124 LLDTLPMLGNVLLLSFLVFFVFGIIGVQLWQGKLRNRC 161
Score = 81.8 bits (193), Expect = 2e-13
Identities = 48/159 (30%), Positives = 91/159 (57%), Gaps = 9/159 (5%)
Query: 1218 TYFETAVITMILLSSLALALED-VHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGF 1276
T+FE + +IL++ + LA+ D + + ++L + F +EM++K +A+G
Sbjct: 3 TWFERISMVIILVNCITLAMYDPLDKRCEKVRCNVLEKFEFFIFGFFLLEMVVKMVAMGV 62
Query: 1277 ---QKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGM 1333
Y + W LDF+I+++ +I +L G+ + +R R LRPLRA++++ +
Sbjct: 63 FGSHGYLQDTWNKLDFVIIVMGVIE--KSLQGSDYLTI---IRAFRVLRPLRAINKVPSI 117
Query: 1334 RVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGK 1372
R++V L+ +P + NVLL+ + + +F I+GVQL+ GK
Sbjct: 118 RILVTLLLDTLPMLGNVLLLSFLVFFVFGIIGVQLWQGK 156
Score = 62.1 bits (144), Expect = 1e-07
Identities = 45/157 (28%), Positives = 74/157 (47%), Gaps = 15/157 (9%)
Query: 1538 FDMIIMLFIGLNMLTMTL-DHYQQ--SETFSAVLDYLNMIFIVIFSSECLLKIFAL---- 1590
F+ I M+ I +N +T+ + D + + VL+ F E ++K+ A+
Sbjct: 5 FERISMVIILVNCITLAMYDPLDKRCEKVRCNVLEKFEFFIFGFFLLEMVVKMVAMGVFG 64
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
+ Y + WN DFV+++ + IEK L ++R +V R LR +
Sbjct: 65 SHGYLQDTWNKLDFVIIVMGV--------IEKSLQGSDYLTIIRAFRVLRPLRAINKVPS 116
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
IR L+ L +LP L N+ LL FLV F+F I G+ +
Sbjct: 117 IRILVTLLLDTLPMLGNVLLLSFLVFFVFGIIGVQLW 153
Score = 59.3 bits (137), Expect = 1e-06
Identities = 41/162 (25%), Positives = 82/162 (50%), Gaps = 9/162 (5%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
++ E+ +F ++ ILL+ + + LE + P L L + +F IF +EM+I +
Sbjct: 478 RMAESRHFSRLIMIAILLNMICMGLEHHNQPQA--LTVTLEKTNIVFVTIFVLEMIINVI 535
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG 1332
+ G Y + D +V++S+ + G + F+++R LR + +R + R Q
Sbjct: 536 SFGIMGYLSQLQNIFDGFVVVLSVTELLLEN-GYARLSVFRSIRLLRIFKLVRPV-RYQ- 592
Query: 1333 MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYF 1374
+ VV+ + + + F +L +F FAI+G+ LF G+++
Sbjct: 593 LLVVIRTMTSVV-TFFGLLF---LFMFAFAILGMNLFGGEFY 630
Score = 52.0 bits (119), Expect = 2e-04
Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 11/93 (11%)
Query: 326 LCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENLYQL--- 382
L NSS Y + GPNP +G SFD A++ F+++T + W ++ L
Sbjct: 223 LTSNSSNCADWNSLYRDCREDGPNPFWGTISFDNIAIAWMVIFQVITLEGWSDVMYLVQD 282
Query: 383 --------FFVVIIFLGSFYLVNLILAIVAMSY 407
+F+++I +G+F+LVNL L ++ M +
Sbjct: 283 THSFWNWIYFIILIVIGAFFLVNLCLVVITMQF 315
Score = 49.6 bits (113), Expect = 9e-04
Identities = 42/150 (28%), Positives = 71/150 (47%), Gaps = 16/150 (10%)
Query: 143 FSLFIITTILVNCILMIMP-------TTPTVESTEVIFTGIYTFESAVKVMARGFILQPF 195
FS I+ IL+N I M + T T+E T ++F I+ E + V++ G +
Sbjct: 485 FSRLIMIAILLNMICMGLEHHNQPQALTVTLEKTNIVFVTIFVLEMIINVISFGIM---- 540
Query: 196 TYLRDAWNWLDFVVIALAYVTMGIDLG--NLAALRTFRVLRALKTVAIVPGLKTIVGAVI 253
YL N D V+ L+ + ++ G L+ R+ R+LR K V V +V +
Sbjct: 541 GYLSQLQNIFDGFVVVLSVTELLLENGYARLSVFRSIRLLRIFKLVRPVRYQLLVVIRTM 600
Query: 254 ESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
SV ++ L MF+ FA++G+ ++ G
Sbjct: 601 TSVVTFFGLLFLFMFA---FAILGMNLFGG 627
Score = 42.7 bits (96), Expect = 0.098
Identities = 30/92 (32%), Positives = 50/92 (54%), Gaps = 6/92 (6%)
Query: 828 KSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVD 887
+S LR+FKL + P L+ ++ RTM ++ +L + +F FA++GM LFG +
Sbjct: 575 RSIRLLRIFKLVR--PVRYQLLVVI-RTMTSVVTFFGLLFLFMFAFAILGMNLFGGEF-- 629
Query: 888 YVDRFPDGDLP-RWNFTDFMHSFMIVFRVLCG 918
Y + +P R NF F+ + + VF+V G
Sbjct: 630 YFPNAENISVPARTNFDSFLWAMVTVFQVRRG 661
Score = 36.7 bits (81), Expect = 6.4
Identities = 13/55 (23%), Positives = 34/55 (61%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLF 881
+++ LR + P++ +L++++ T+ LGN+ + ++ F+F ++G+QL+
Sbjct: 99 IRAFRVLRPLRAINKVPSIRILVTLLLDTLPMLGNVLLLSFLVFFVFGIIGVQLW 153
>UniRef50_A3UK17 Cluster: Cation channel family protein; n=2;
Hyphomonadaceae|Rep: Cation channel family protein -
Oceanicaulis alexandrii HTCC2633
Length = 292
Score = 82.2 bits (194), Expect = 1e-13
Identities = 52/161 (32%), Positives = 85/161 (52%), Gaps = 12/161 (7%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
+L+ + F + +IL+++ L L LP I+ +L + D F +E+L+K L
Sbjct: 15 RLLASAAFRNTITALILINAAILGLLTYPLPE--IVVQVLTFADHAIIAAFVVEILLK-L 71
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG 1332
+ +F + W W DF +V +SLI A G AF +R LR LR R S +
Sbjct: 72 IVHRLNFFKSGWNWFDFAVVAISLIP-------AAG--AFTVLRALRVLRLFRLFSVIPE 122
Query: 1333 MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
MR VV AL +AIP + ++LV + + + ++MG +LF+G +
Sbjct: 123 MRSVVEALGKAIPGMGAIMLVLGVIFYVASVMGAKLFSGTH 163
Score = 60.5 bits (140), Expect = 5e-07
Identities = 63/266 (23%), Positives = 111/266 (41%), Gaps = 38/266 (14%)
Query: 1524 RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSEC 1583
+P+ + ++ F I I +N + L Y E VL + + I F E
Sbjct: 8 KPKNALERLLASAAFRNTITALILINAAILGLLTYPLPEIVVQVLTFADHAIIAAFVVEI 67
Query: 1584 LLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLR 1643
LLK+ R ++F WN FDF VV S++ + T+LR +RV R+ R
Sbjct: 68 LLKLIVHRLNFFKSGWNWFDFAVVAISLIPAA---------GAFTVLRALRVL---RLFR 115
Query: 1644 LVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFK 1703
L +R+++ AL ++P + I L+L ++ ++ ++ G F G + F
Sbjct: 116 LFSVIPEMRSVVEALGKAIPGMGAIMLVLGVIFYVASVMGAKLF------SGTHPQF-FG 168
Query: 1704 TFVQSMILLFQMSTSAGWD-GVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLV 1762
S LFQ+ T W GV +I E Y + +++
Sbjct: 169 DLGGSAYTLFQVMTLESWSMGVARPVIAEH------------------PYAWIYFVGFVI 210
Query: 1763 ISFLIVINMYIAVILENYSQATEDVQ 1788
++ V+N++IAVI+++ D +
Sbjct: 211 VTSFAVLNLFIAVIVDSMQSKHFDAE 236
Score = 59.3 bits (137), Expect = 1e-06
Identities = 35/154 (22%), Positives = 76/154 (49%), Gaps = 7/154 (4%)
Query: 137 ILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVIFT-GIYTFESA--VKVMARGFILQ 193
+L F I IL+N ++ + T P E + T + +A V+++ + I+
Sbjct: 16 LLASAAFRNTITALILINAAILGLLTYPLPEIVVQVLTFADHAIIAAFVVEILLK-LIVH 74
Query: 194 PFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVI 253
+ + WNW DF V+A++ + G LR RVLR + +++P ++++V A+
Sbjct: 75 RLNFFKSGWNWFDFAVVAISLIPAA---GAFTVLRALRVLRLFRLFSVIPEMRSVVEALG 131
Query: 254 ESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQ 287
+++ + ++++ V ++MG +++ G Q
Sbjct: 132 KAIPGMGAIMLVLGVIFYVASVMGAKLFSGTHPQ 165
Score = 38.3 bits (85), Expect = 2.1
Identities = 16/62 (25%), Positives = 35/62 (56%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L++ LR+F+L P + ++ +G+ + +G + VL +I ++ +VMG +LF +
Sbjct: 105 LRALRVLRLFRLFSVIPEMRSVVEALGKAIPGMGAIMLVLGVIFYVASVMGAKLFSGTHP 164
Query: 887 DY 888
+
Sbjct: 165 QF 166
>UniRef50_A3W0R4 Cluster: Voltage-gated sodium channel; n=8;
Alphaproteobacteria|Rep: Voltage-gated sodium channel -
Roseovarius sp. 217
Length = 306
Score = 81.0 bits (191), Expect = 3e-13
Identities = 48/166 (28%), Positives = 87/166 (52%), Gaps = 11/166 (6%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEM 1267
R + + +E +T ++ +I+ +++ L L I D LY +DR+ VIF +E+
Sbjct: 35 RARLRRFVERPSVQTFIMGVIIFNAITLGLSTSDYMQAHI-GDFLYTIDRVVLVIFVLEL 93
Query: 1268 LIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAM 1327
LIK A G K+F N+W DF +V + L+ ++ +R LR +R +R +
Sbjct: 94 LIKLYAYGL-KFFRNSWNIFDFCVVSIGLLPQTDSM---------SALRGLRVIRAMRLL 143
Query: 1328 SRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
S + MR VV AL+ A+P + V+++ I + +FA+M ++ +
Sbjct: 144 SVIPQMRAVVQALLDALPGMGAVIIMISIVFYVFAVMATIMYGNSF 189
Score = 60.5 bits (140), Expect = 5e-07
Identities = 37/146 (25%), Positives = 80/146 (54%), Gaps = 10/146 (6%)
Query: 141 PLFSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVM-ARGFILQPFTY-- 197
P FI+ I+ N I + + T+ +++ F +YT + V V+ +++ + Y
Sbjct: 45 PSVQTFIMGVIIFNAITLGLSTSDYMQAHIGDF--LYTIDRVVLVIFVLELLIKLYAYGL 102
Query: 198 --LRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIES 255
R++WN DF V+++ + +++ALR RV+RA++ ++++P ++ +V A++++
Sbjct: 103 KFFRNSWNIFDFCVVSIGLLPQ---TDSMSALRGLRVIRAMRLLSVIPQMRAVVQALLDA 159
Query: 256 VKNLRDVIILTMFSLSVFALMGLQIY 281
+ + VII+ VFA+M +Y
Sbjct: 160 LPGMGAVIIMISIVFYVFAVMATIMY 185
Score = 60.5 bits (140), Expect = 5e-07
Identities = 54/184 (29%), Positives = 93/184 (50%), Gaps = 21/184 (11%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVE 1597
F M +++F + + T D+ Q L ++ + +VIF E L+K++A +F
Sbjct: 50 FIMGVIIFNAITLGLSTSDYMQAH--IGDFLYTIDRVVLVIFVLELLIKLYAYGLKFFRN 107
Query: 1598 PWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFA 1657
WN+FDF VV SI L +D S + LR +RV R +RL+ +R ++ A
Sbjct: 108 SWNIFDFCVV--SIGLLPQTD-------SMSALRGLRVI---RAMRLLSVIPQMRAVVQA 155
Query: 1658 LAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMST 1717
L +LP + + +++ +V ++FA+ M+ M+ G D + F T +S+ LFQ+ T
Sbjct: 156 LLDALPGMGAVIIMISIVFYVFAV--MATIMY----GNSFDEW-FGTLGRSLYSLFQIMT 208
Query: 1718 SAGW 1721
W
Sbjct: 209 LESW 212
>UniRef50_A7STF7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 534
Score = 80.2 bits (189), Expect = 5e-13
Identities = 58/239 (24%), Positives = 106/239 (44%), Gaps = 14/239 (5%)
Query: 1258 IFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFV--AALCGAGGIQA-FKT 1314
+F V+F IE+L+K+ +GF+ +F W W DF+++ + + V A+ Q+
Sbjct: 290 LFLVLFNIEILLKFYTIGFKDFFRGFWNWFDFLVIGAATLALVIEASFISLQSSQSVLDF 349
Query: 1315 MRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYF 1374
+ LR LR + + +++ +V++ L+Q P+I + I + I+AI+G++LF G
Sbjct: 350 LMVLRVLRLAKIIGQVRRFQVIIGTLMQIGPAITTYGAIMFILYYIYAIVGIELFGGLIL 409
Query: 1375 KCVDMN-HTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMN 1433
K N ++T++ + + Y NFD + KA LF + W I
Sbjct: 410 KEAPTNDNSTVNSTFCGNIKLKGSDFYQDRYCSNNFDDILKAMKLLFDLTVVNQWHVITQ 469
Query: 1434 DAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLE 1492
+ TN + LY LN+F+ I++ F + + G E
Sbjct: 470 GF----------VLVTNKWARLYFLSFHMICVIVVLNIFVAFILEAFMLEYSISHGKFE 518
Score = 60.5 bits (140), Expect = 5e-07
Identities = 55/224 (24%), Positives = 110/224 (49%), Gaps = 15/224 (6%)
Query: 1569 DYLNMIFIVIFSSECLLKIFALRYHYFVEP-WNLFDFVVVMFSILSLVLSDIIEKYFVSP 1627
DY ++F+V+F+ E LLK + + + F WN FDF+V+ + L+LV+ S
Sbjct: 286 DY-EILFLVLFNIEILLKFYTIGFKDFFRGFWNWFDFLVIGAATLALVIEASFISLQSSQ 344
Query: 1628 TLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
++L + V +V R+ +++ + + ++ L PA+ ++F++ +I+AI G+ F
Sbjct: 345 SVLDFLMVLRVLRLAKIIGQVRRFQVIIGTLMQIGPAITTYGAIMFILYYIYAIVGIELF 404
Query: 1688 --MHVKDKGGLDDVYNFKTFVQSMIL----LFQ-MSTSAGWDGVLDGIINEEECDLPDNE 1740
+ +K+ D+ TF ++ L +Q S +D +L + + DL
Sbjct: 405 GGLILKEAPTNDNSTVNSTFCGNIKLKGSDFYQDRYCSNNFDDILKAM--KLLFDLTVVN 462
Query: 1741 RGSPGNCGSATI----GITYLLSYLVISFLIVINMYIAVILENY 1780
+ G + Y LS+ +I ++V+N+++A ILE +
Sbjct: 463 QWHVITQGFVLVTNKWARLYFLSFHMICVIVVLNIFVAFILEAF 506
Score = 49.6 bits (113), Expect = 9e-04
Identities = 36/165 (21%), Positives = 73/165 (44%), Gaps = 17/165 (10%)
Query: 133 VAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMARGFIL 192
V+I++ V F F I N I + + E++F ++ E +K GF
Sbjct: 255 VSIFLAVVLFFVYFFDLVIFANAIFIALDAN----DYEILFLVLFNIEILLKFYTIGFK- 309
Query: 193 QPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAA---------LRTFRVLRALKTVAIVP 243
+ R WNW DF+VI A + + I+ ++ L RVLR K + V
Sbjct: 310 ---DFFRGFWNWFDFLVIGAATLALVIEASFISLQSSQSVLDFLMVLRVLRLAKIIGQVR 366
Query: 244 GLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQK 288
+ I+G +++ + + ++A++G++++ G++ ++
Sbjct: 367 RFQVIIGTLMQIGPAITTYGAIMFILYYIYAIVGIELFGGLILKE 411
Score = 41.5 bits (93), Expect = 0.23
Identities = 26/118 (22%), Positives = 58/118 (49%), Gaps = 2/118 (1%)
Query: 1262 IFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRAL 1321
+F + + W K++ + + ++++++ ++ + + T+R R
Sbjct: 83 VFCVRLFHVWSFAAGVKFWRDKKNAILLVVIVLTFLDMIMYVIFKEAEVDAHTIRWTRIF 142
Query: 1322 RPLRAMSRMQGMRV--VVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCV 1377
RPL ++ +G ++ V + + +P I NVL++ L+ +FA + V+LF GK K V
Sbjct: 143 RPLYLINISEGRQIRRAVRNIRRTLPEIANVLILLLLMIALFAQICVKLFGGKNLKDV 200
>UniRef50_A7RF81 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 216
Score = 78.6 bits (185), Expect = 2e-12
Identities = 52/227 (22%), Positives = 108/227 (47%), Gaps = 30/227 (13%)
Query: 1571 LNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEK-------- 1622
L+ F+ I+ E +LK++AL+ +F WN+ D +V+F+ + +L I++
Sbjct: 6 LDNCFLAIYFVEIVLKLYALQETFFKSGWNIMDLTIVLFTTMDFLLPLIVQNMGSFDVAA 65
Query: 1623 YFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIF 1682
F + R +R + RVLR ++ K ++ ++ + S AL I +L L +++FA+
Sbjct: 66 IFRLLRMFRAIRALRALRVLRTIRFLKNLQVIMTTILKSFRALSTIVMLQGLFLYMFAVI 125
Query: 1683 GMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERG 1742
G F V + F + ++ LFQ+ T W + +N++
Sbjct: 126 GRGLFYDVSPE-------RFGSLGKAFFTLFQLITLDDWFYMYSDAVNKDP--------- 169
Query: 1743 SPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQE 1789
+ I YL+ Y+++ I +N+++AV+++N+ + ++E
Sbjct: 170 ------KYSYIILYLIIYIILENFIFMNLFVAVLVDNFQRTLTALEE 210
Score = 59.7 bits (138), Expect = 8e-07
Identities = 53/227 (23%), Positives = 101/227 (44%), Gaps = 32/227 (14%)
Query: 1255 MDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKT 1314
+D F I+F+E+++K AL + +F + W +D IV+ + ++F+ L + +F
Sbjct: 6 LDNCFLAIYFVEIVLKLYALQ-ETFFKSGWNIMDLTIVLFTTMDFLLPLI-VQNMGSFDV 63
Query: 1315 MRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIF-AIMGVQLFAGKY 1373
R LR RA+ ++ +RV+ + I + N+ ++ F A+ + + G +
Sbjct: 64 AAIFRLLRMFRAIRALRALRVL-----RTIRFLKNLQVIMTTILKSFRALSTIVMLQGLF 118
Query: 1374 FKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMN 1433
+ L +++ P++ F +GKA+ LFQ+ T W + +
Sbjct: 119 LYMFAVIGRGLFYDVSPER----------------FGSLGKAFFTLFQLITLDDWFYMYS 162
Query: 1434 DAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNF 1480
DA V + P Y+ LY +NLF+ V++DNF
Sbjct: 163 DA-----VNKDP---KYSYIILYLIIYIILENFIFMNLFVAVLVDNF 201
Score = 39.1 bits (87), Expect = 1.2
Identities = 17/63 (26%), Positives = 37/63 (58%)
Query: 226 ALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVL 285
A+R R LR L+T+ + L+ I+ +++S + L +++L L +FA++G ++ V
Sbjct: 75 AIRALRALRVLRTIRFLKNLQVIMTTILKSFRALSTIVMLQGLFLYMFAVIGRGLFYDVS 134
Query: 286 TQK 288
++
Sbjct: 135 PER 137
>UniRef50_Q4STU8 Cluster: Chromosome undetermined SCAF14113, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14113,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 372
Score = 77.4 bits (182), Expect = 4e-12
Identities = 33/53 (62%), Positives = 39/53 (73%), Gaps = 1/53 (1%)
Query: 894 DGDLPRWNFTDFMHSFMIVFRVLCGEWIESMWDCM-LVGDVSCIPFFLATVVI 945
D LPRW+ DF HSF+IVFRVLCGEWIE+MWDCM + G CI F+ +VI
Sbjct: 315 DCTLPRWHMKDFFHSFLIVFRVLCGEWIETMWDCMEVAGQPLCILVFMLVMVI 367
Score = 76.6 bits (180), Expect = 7e-12
Identities = 39/101 (38%), Positives = 63/101 (62%), Gaps = 2/101 (1%)
Query: 1521 PRW-RPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIF 1579
P W R + +V +V D D+ I + I LN L M ++HY ++ F+ +L N++F IF
Sbjct: 54 PCWLRVKQLVKIMVMDPFLDLAITICIVLNTLFMAMEHYPMTDEFNGMLSIGNLVFSGIF 113
Query: 1580 SSECLLKIFAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDI 1619
++E +LKI AL Y+YF WN+FD ++V S++ L LS++
Sbjct: 114 TAEMVLKIIALDPYYYFQTGWNIFDSIIVSLSLMELGLSNV 154
Score = 73.7 bits (173), Expect = 5e-11
Identities = 29/60 (48%), Positives = 43/60 (71%)
Query: 772 FCVWDCCWLWLEFQKYVALLVFDPFVELFITLCIVVNTLFMALDHHNMDKDMDKALKSGN 831
F VW+CC WL ++ V ++V DPF++L IT+CIV+NTLFMA++H+ M + + L GN
Sbjct: 47 FLVWECCPCWLRVKQLVKIMVMDPFLDLAITICIVLNTLFMAMEHYPMTDEFNGMLSIGN 106
Score = 52.8 bits (121), Expect = 9e-05
Identities = 28/112 (25%), Positives = 62/112 (55%), Gaps = 12/112 (10%)
Query: 130 IRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVESTE-------VIFTGIYTFESA 182
++++ +++ P L I I++N + M M P + ++F+GI+T E
Sbjct: 59 VKQLVKIMVMDPFLDLAITICIVLNTLFMAMEHYPMTDEFNGMLSIGNLVFSGIFTAEMV 118
Query: 183 VKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGI-DLGNLAALRTFRVL 233
+K++A L P+ Y + WN D ++++L+ + +G+ ++ L+ LR+FR++
Sbjct: 119 LKIIA----LDPYYYFQTGWNIFDSIIVSLSLMELGLSNVEGLSVLRSFRLV 166
Score = 46.4 bits (105), Expect = 0.008
Identities = 29/103 (28%), Positives = 52/103 (50%), Gaps = 4/103 (3%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
++ + + + A+ I+L++L +A+E H P +L + +F+ IF EM++K +A
Sbjct: 66 MVMDPFLDLAITICIVLNTLFMAME--HYPMTDEFNGMLSIGNLVFSGIFTAEMVLKIIA 123
Query: 1274 LGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMR 1316
L YF W D IIV +SL+ L G+ ++ R
Sbjct: 124 LDPYYYFQTGWNIFDSIIVSLSLMEL--GLSNVEGLSVLRSFR 164
>UniRef50_Q4QE45 Cluster: Putative uncharacterized protein; n=3;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania major
Length = 1414
Score = 77.0 bits (181), Expect = 5e-12
Identities = 111/596 (18%), Positives = 237/596 (39%), Gaps = 56/596 (9%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
+RL +++ + ++ + + +AL E HL + L+ ++ + V+F +E
Sbjct: 638 VRLLLLRVLGSPFYTLISTLCVAIGVVALFFERRHLDADT--ERTLHLVNIVCLVVFVVE 695
Query: 1267 MLIKWLALGF--------QKYFTNAWCWL--DFIIVMVSLINFVAALCGAGGIQAFKTMR 1316
M++KWLA G + ++ +A + ++ ++F A + A+ +R
Sbjct: 696 MVMKWLAYGVVTQGWGDGEDHYRDARSRYMPAYFRYPLNWVDFAANGLALAAV-AYPPLR 754
Query: 1317 TLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKC 1376
R +R R + + LV+ + V + ++ FA+ +Q+FAG F+C
Sbjct: 755 VGRVIRTARLFTTQERPNKSFVELVKVLRHTVRVAPLIFFLYVAFAVTAMQMFAGGLFRC 814
Query: 1377 VDMNHTTLSHEIIPDKNACTLENYT----------WENSPMNFDHVGKAYLCLFQVATFK 1426
D TT S E D N T+ YT W + ++D G A L +F + T
Sbjct: 815 SDAAVTT-SAECFGDYNT-TVMGYTGSTTSVRKRRWVRAGFHYDSFGPALLSVFAMTTVN 872
Query: 1427 GWIQIMNDAIDSREVGRQPIRETNIYM--YLYXXXXXXXXXXXTL-NLFI----GVIIDN 1479
W M+D + + + Y+ ++ T+ +FI GV++D+
Sbjct: 873 HWGNFMDDVVAIKHT-MMAYNHSGYYVAFFIVALLLIRFFAVRTIAAVFIAELRGVVMDS 931
Query: 1480 FNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFD 1539
++ ++ + + +++ P A R R + + FD
Sbjct: 932 LG-TAQRTPHQTRFVVSRECIAHLTQLQRFLPPLP-TAASRLCHRILSAQPAQWPNTVFD 989
Query: 1540 MIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPW 1599
++ + + + H +S ++ ++ + + + +E LL + A Y
Sbjct: 990 AVVQGVLVVVCGFVAATHAGESLWQKRMIVAVDCVAVALCGAEVLLGMLAYGVRYLTRAS 1049
Query: 1600 NLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALA 1659
D V+ + ++ + + ++ +++++ A L L+ + I+ LL + A
Sbjct: 1050 YAADVVLFVLMVVGIAAPSL--RFVTVVIFVKLIKAAST--ALALLPATRHIQMLLSSGA 1105
Query: 1660 MSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKG-GLDDVYNFKTFVQSMILLFQMSTS 1718
++L LV++ +A+ G + G L D NF T + S+++L ST
Sbjct: 1106 LAL-----------LVLYAYAVVGTLLLGDIAPDGVYLTDTRNFSTVIGSLLVLLDCSTF 1154
Query: 1719 AGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIA 1774
W V+ + C + CG + + +S++VI L+V + +A
Sbjct: 1155 DQWHLVMHACFDGAAC-----HSDASATCGHTYSAVIFFVSFIVIESLVVSQLMLA 1205
Score = 41.5 bits (93), Expect = 0.23
Identities = 30/151 (19%), Positives = 67/151 (44%), Gaps = 11/151 (7%)
Query: 1224 VITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNA 1283
++ M+L S L L V + +L+ + V F + ++ ++ G + +
Sbjct: 329 ILLMVLSVSSVLLLAVVSTSTPDLAARLLHTISAALAVFFIVPAALRLISFGVVRASVDV 388
Query: 1284 WCWLDFIIVMVSLINFVA-ALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQ 1342
W + D + + ++ A +L + A + +R +R + L + R +
Sbjct: 389 WNYADLLAAVSGVLELAAPSLFNYRVVGAVRVLRCVRVAKYLCPLYRYE----------Y 438
Query: 1343 AIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
+ S+ ++LL+ ++A++G+QLFAG Y
Sbjct: 439 RLKSLLSLLLLTSAILTLYALLGMQLFAGTY 469
>UniRef50_A6W2Y2 Cluster: Ion transport protein; n=12;
Gammaproteobacteria|Rep: Ion transport protein -
Marinomonas sp. MWYL1
Length = 276
Score = 75.8 bits (178), Expect = 1e-11
Identities = 56/190 (29%), Positives = 93/190 (48%), Gaps = 19/190 (10%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL--RYHYF 1595
F I+ I + LT+ Y ++YL+ V F +E L+ A + +F
Sbjct: 22 FQGFIISIIIVAALTVGAKTYSLPYGIDTAINYLDNFITVFFLAELSLRFIACDDKRRFF 81
Query: 1596 VEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLL 1655
+PWN+FD V+V+ S++ + +++I V R+ +V RVLRLV +R L+
Sbjct: 82 KDPWNVFDTVIVIGSLVPISNTEMI----------LVARLLRVFRVLRLVSIIPDLRFLI 131
Query: 1656 FALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQM 1715
AL ++P + I LL+F++ +IFA G FF V + D SM+ LF++
Sbjct: 132 NALIKAIPKMGYIALLMFIIFYIFAAVGSIFFHQVNETLWGD-------IAISMLTLFRV 184
Query: 1716 STSAGWDGVL 1725
+T W V+
Sbjct: 185 ATFEDWTDVM 194
Score = 69.7 bits (163), Expect = 7e-10
Identities = 42/161 (26%), Positives = 85/161 (52%), Gaps = 10/161 (6%)
Query: 1210 KTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLI 1269
K ++ + +F+ +I++I++++L + + LP+ + + Y+D TV F E+ +
Sbjct: 12 KIKRIERSAWFQGFIISIIIVAALTVGAKTYSLPYG--IDTAINYLDNFITVFFLAELSL 69
Query: 1270 KWLALGFQK-YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMS 1328
+++A ++ +F + W D +IV+ SL+ + R LR R LR +S
Sbjct: 70 RFIACDDKRRFFKDPWNVFDTVIVIGSLVPI-------SNTEMILVARLLRVFRVLRLVS 122
Query: 1329 RMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
+ +R ++NAL++AIP + + L+ I + IFA +G F
Sbjct: 123 IIPDLRFLINALIKAIPKMGYIALLMFIIFYIFAAVGSIFF 163
Score = 46.0 bits (104), Expect = 0.011
Identities = 21/81 (25%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Query: 197 YLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESV 256
+ +D WN D V++ + V + + + R RV R L+ V+I+P L+ ++ A+I+++
Sbjct: 80 FFKDPWNVFDTVIVIGSLVPIS-NTEMILVARLLRVFRVLRLVSIIPDLRFLINALIKAI 138
Query: 257 KNLRDVIILTMFSLSVFALMG 277
+ + +L +FA +G
Sbjct: 139 PKMGYIALLMFIIFYIFAAVG 159
>UniRef50_UPI0000EBD484 Cluster: PREDICTED: similar to N-type
calcium channel alpha1B subunit, partial; n=1; Bos
taurus|Rep: PREDICTED: similar to N-type calcium channel
alpha1B subunit, partial - Bos taurus
Length = 767
Score = 75.4 bits (177), Expect = 2e-11
Identities = 51/164 (31%), Positives = 86/164 (52%), Gaps = 25/164 (15%)
Query: 216 TMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFAL 275
T G D +L LR RVLR LK V+ +P L+ ++ ++++++ L + +L F++ +FA+
Sbjct: 139 TAGTDF-DLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAI 197
Query: 276 MGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWERFCQNETNWYGEGGDYPLCGNSSGAGQ 335
+GL+ YMG + C FP N TD + GD+P CG + A
Sbjct: 198 IGLEFYMGKFHKAC---FP------NSTDAD-------------PVGDFP-CGREAPARL 234
Query: 336 CEPGYVCLQGFGPNPNYGYTSFDTFGWAFLSAFRLMTQDYWENL 379
CE C + + PN+G T+FD +A L+ F+ +T + W ++
Sbjct: 235 CEGDTECRE-YWAGPNFGITNFDNILFAILTVFQCITMEGWTDI 277
Score = 56.0 bits (129), Expect = 1e-05
Identities = 41/146 (28%), Positives = 72/146 (49%), Gaps = 15/146 (10%)
Query: 1303 LCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFA 1362
L AG +T+R +R LRPL+ +S + ++VV+ ++++A+ + + L+ L+FA
Sbjct: 137 LATAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFA 196
Query: 1363 IMGVQLFAGKYFKCVDMNHTTLS------------HEIIPDKNACTLENYTWENSPM-NF 1409
I+G++ + GK+ K N T + C E + N + NF
Sbjct: 197 IIGLEFYMGKFHKACFPNSTDADPVGDFPCGREAPARLCEGDTECR-EYWAGPNFGITNF 255
Query: 1410 DHVGKAYLCLFQVATFKGWIQIM-ND 1434
D++ A L +FQ T +GW I+ ND
Sbjct: 256 DNILFAILTVFQCITMEGWTDILYND 281
Score = 46.4 bits (105), Expect = 0.008
Identities = 22/59 (37%), Positives = 36/59 (61%)
Query: 1630 LRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
LR +R +V R L+LV G ++ +L ++ ++ L I LLLF + +FAI G+ F+M
Sbjct: 146 LRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYM 204
>UniRef50_Q5QZT4 Cluster: Kef-type K+ transport system, NAD-binding
component; n=9; Proteobacteria|Rep: Kef-type K+ transport
system, NAD-binding component - Idiomarina loihiensis
Length = 275
Score = 75.4 bits (177), Expect = 2e-11
Identities = 47/165 (28%), Positives = 89/165 (53%), Gaps = 10/165 (6%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
++ + F+L N FE V+ +I++S+L + + LP + Y +D T+ F IE
Sbjct: 5 IKKQLFQLKSNKAFEALVVAVIIISALEIGAKTYELP--AFANSLTYGLDLFITLFFLIE 62
Query: 1267 MLIKWLALGFQK-YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLR 1325
+ I+++A +K +F + W D ++V++SLI + R +R R LR
Sbjct: 63 ISIRFIAEDNKKAFFKDGWNVFDTLVVIMSLIPI-------NDSELALLARLVRIFRVLR 115
Query: 1326 AMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
+S + +R ++N+L++A+P + V+L+ I + I+A +G LFA
Sbjct: 116 MISIIPELRTLINSLLKALPQMGYVVLLMFIIFYIYAAVGSYLFA 160
Score = 65.7 bits (153), Expect = 1e-08
Identities = 46/198 (23%), Positives = 101/198 (51%), Gaps = 19/198 (9%)
Query: 1529 VFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIF 1588
+F++ ++K F+ +++ I ++ L + Y+ +++ L++ + F E ++
Sbjct: 9 LFQLKSNKAFEALVVAVIIISALEIGAKTYELPAFANSLTYGLDLFITLFFLIEISIRFI 68
Query: 1589 AL--RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVK 1646
A + +F + WN+FD +VV+ S++ + S++ L R+VR+ RVLR++
Sbjct: 69 AEDNKKAFFKDGWNVFDTLVVIMSLIPINDSELA-------LLARLVRIF---RVLRMIS 118
Query: 1647 GAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFV 1706
+RTL+ +L +LP + + LL+F++ +I+A G F + + + +
Sbjct: 119 IIPELRTLINSLLKALPQMGYVVLLMFIIFYIYAAVGSYLFADI-------NPFLWDNIA 171
Query: 1707 QSMILLFQMSTSAGWDGV 1724
SM+ LF++ T W +
Sbjct: 172 TSMLTLFRVMTFEDWTDI 189
Score = 48.8 bits (111), Expect = 0.001
Identities = 21/89 (23%), Positives = 52/89 (58%), Gaps = 3/89 (3%)
Query: 197 YLRDAWNWLDFVVIALAYVTMGIDLGNLAAL-RTFRVLRALKTVAIVPGLKTIVGAVIES 255
+ +D WN D +V+ ++ + I+ LA L R R+ R L+ ++I+P L+T++ +++++
Sbjct: 76 FFKDGWNVFDTLVVIMSLIP--INDSELALLARLVRIFRVLRMISIIPELRTLINSLLKA 133
Query: 256 VKNLRDVIILTMFSLSVFALMGLQIYMGV 284
+ + V++L ++A +G ++ +
Sbjct: 134 LPQMGYVVLLMFIIFYIYAAVGSYLFADI 162
>UniRef50_A1RP00 Cluster: Ion transport protein; n=12;
Proteobacteria|Rep: Ion transport protein - Shewanella
sp. (strain W3-18-1)
Length = 295
Score = 74.5 bits (175), Expect = 3e-11
Identities = 43/167 (25%), Positives = 92/167 (55%), Gaps = 11/167 (6%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIE 1266
L+ + L+E +F ++T+IL++++ L +E +L +D++ +F +E
Sbjct: 12 LQARVISLVEQNWFGHFILTLILINAVQLGME-TSASLMAQYGTLLMSLDKVLLSVFVVE 70
Query: 1267 MLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRA 1326
+L++ A K+F + W DF +++++LI A G A +R+LR LR LR
Sbjct: 71 LLLRIYAYR-GKFFKDPWSVFDFTVIVIALI-------PASGPLA--VLRSLRVLRVLRV 120
Query: 1327 MSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
++ + M+ VV+AL+ ++P + ++ V L+ + +FA++ ++F +
Sbjct: 121 LTIVPSMKRVVSALLGSLPGLASIATVLLLIYYVFAVIATKIFGDAF 167
Score = 71.7 bits (168), Expect = 2e-10
Identities = 52/197 (26%), Positives = 93/197 (47%), Gaps = 20/197 (10%)
Query: 1526 QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQ-SETFSAVLDYLNMIFIVIFSSECL 1584
QA V +V F I+ I +N + + ++ + +L L+ + + +F E L
Sbjct: 13 QARVISLVEQNWFGHFILTLILINAVQLGMETSASLMAQYGTLLMSLDKVLLSVFVVELL 72
Query: 1585 LKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRL 1644
L+I+A R +F +PW++FDF V++ +++ + L V+R +V RVLR+
Sbjct: 73 LRIYAYRGKFFKDPWSVFDFTVIVIALIP------------ASGPLAVLRSLRVLRVLRV 120
Query: 1645 VKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKT 1704
+ ++ ++ AL SLP L +I +L L+ ++FA+ F + F T
Sbjct: 121 LTIVPSMKRVVSALLGSLPGLASIATVLLLIYYVFAVIATKIFGDAFPEW-------FGT 173
Query: 1705 FVQSMILLFQMSTSAGW 1721
S LFQ+ T W
Sbjct: 174 IADSFYTLFQIMTLESW 190
Score = 67.7 bits (158), Expect = 3e-09
Identities = 46/168 (27%), Positives = 85/168 (50%), Gaps = 18/168 (10%)
Query: 123 ILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPTTPTVE--------STEVIFT 174
+LD ++ I ++ F FI+T IL+N + + M T+ ++ S + +
Sbjct: 5 LLDVPTGLQARVISLVEQNWFGHFILTLILINAVQLGMETSASLMAQYGTLLMSLDKVLL 64
Query: 175 GIYTFESAVKVMA-RGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVL 233
++ E +++ A RG + +D W+ DF VI +A + G LA LR+ RVL
Sbjct: 65 SVFVVELLLRIYAYRG------KFFKDPWSVFDFTVIVIALIPAS---GPLAVLRSLRVL 115
Query: 234 RALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
R L+ + IVP +K +V A++ S+ L + + + VFA++ +I+
Sbjct: 116 RVLRVLTIVPSMKRVVSALLGSLPGLASIATVLLLIYYVFAVIATKIF 163
Score = 37.1 bits (82), Expect = 4.9
Identities = 17/68 (25%), Positives = 38/68 (55%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+S LRV ++ P++ ++S + ++ L ++ VL +I ++FAV+ ++FG +
Sbjct: 109 LRSLRVLRVLRVLTIVPSMKRVVSALLGSLPGLASIATVLLLIYYVFAVIATKIFGDAFP 168
Query: 887 DYVDRFPD 894
++ D
Sbjct: 169 EWFGTIAD 176
>UniRef50_Q9GZR0 Cluster: Voltage-gated sodium channel; n=18;
Tetrapoda|Rep: Voltage-gated sodium channel - Homo
sapiens (Human)
Length = 50
Score = 74.5 bits (175), Expect = 3e-11
Identities = 29/43 (67%), Positives = 35/43 (81%)
Query: 1254 YMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSL 1296
Y D++FT IF +EML+KW A GF K+FTNAWCWLDF+IV V L
Sbjct: 2 YADKVFTYIFILEMLLKWTAYGFVKFFTNAWCWLDFLIVAVPL 44
>UniRef50_Q47SZ6 Cluster: Putative uncharacterized protein; n=1;
Thermobifida fusca YX|Rep: Putative uncharacterized
protein - Thermobifida fusca (strain YX)
Length = 312
Score = 74.1 bits (174), Expect = 3e-11
Identities = 39/112 (34%), Positives = 61/112 (54%), Gaps = 8/112 (7%)
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRT 229
E F + E ++++ARG + + RD WNW D VV+ ++ + + G A LR
Sbjct: 54 EGCFLTFFVLELTLRILARGVV-----FFRDVWNWFDLVVVGISLIPLA---GGFAVLRL 105
Query: 230 FRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
RVLR L+ V+++P L+ IV A+ SV L VI L + A+MG Q++
Sbjct: 106 VRVLRLLRLVSVLPSLRYIVDALFRSVPGLGTVIALLFVVMYTAAIMGEQLF 157
Score = 73.3 bits (172), Expect = 6e-11
Identities = 47/158 (29%), Positives = 84/158 (53%), Gaps = 13/158 (8%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYM-DRIFTVIFFIEMLIKW 1271
+ +++ +F+ V+ +IL + + L LE R + D + + + F F +E+ ++
Sbjct: 12 RFVDSQWFQNLVVAVILANGVVLGLETYE--DRFVWLDRNWMLIEGCFLTFFVLELTLRI 69
Query: 1272 LALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQ 1331
LA G +F + W W D ++V +SLI AGG F +R +R LR LR +S +
Sbjct: 70 LARGVV-FFRDVWNWFDLVVVGISLIPL------AGG---FAVLRLVRVLRLLRLVSVLP 119
Query: 1332 GMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
+R +V+AL +++P + V+ + + AIMG QLF
Sbjct: 120 SLRYIVDALFRSVPGLGTVIALLFVVMYTAAIMGEQLF 157
Score = 69.7 bits (163), Expect = 7e-10
Identities = 81/310 (26%), Positives = 133/310 (42%), Gaps = 47/310 (15%)
Query: 1523 WRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETF-SAVLDYLNMIFIVIFSS 1581
W + + V + F +++ I N + + L+ Y+ + + F+ F
Sbjct: 4 WAWRDTLARFVDSQWFQNLVVAVILANGVVLGLETYEDRFVWLDRNWMLIEGCFLTFFVL 63
Query: 1582 ECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRV 1641
E L+I A +F + WN FD VVV S++ L + LR+VRV R+
Sbjct: 64 ELTLRILARGVVFFRDVWNWFDLVVVGISLIPLAGGFAV---------LRLVRVL---RL 111
Query: 1642 LRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYN 1701
LRLV +R ++ AL S+P L + LLF+VM+ AI G F G + Y
Sbjct: 112 LRLVSVLPSLRYIVDALFRSVPGLGTVIALLFVVMYTAAIMGEQLF------GEISPQY- 164
Query: 1702 FKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYL 1761
F ++ LF + T W + D +I + A + +SY+
Sbjct: 165 FGNLGTTLYTLFMLLTMENWPDISDSVIED------------------APYAWIFFVSYI 206
Query: 1762 VISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSD 1821
V+S IV+N+ I VI+ + E+V +D ++ E+ Q +R +QLSD
Sbjct: 207 VVSAFIVLNLIIGVIV---TTMEEEVSAPRWAEDQEI--ELHQH----EQVMLRLEQLSD 257
Query: 1822 FLDVLEPPLQ 1831
+ VL L+
Sbjct: 258 QVAVLSAQLR 267
Score = 39.1 bits (87), Expect = 1.2
Identities = 16/51 (31%), Positives = 32/51 (62%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGK 883
LR+ +L P+L ++ + R++ LG + +L ++++ A+MG QLFG+
Sbjct: 109 LRLLRLVSVLPSLRYIVDALFRSVPGLGTVIALLFVVMYTAAIMGEQLFGE 159
>UniRef50_A0NR80 Cluster: Ion transport protein; n=11; Bacteria|Rep:
Ion transport protein - Stappia aggregata IAM 12614
Length = 301
Score = 73.7 bits (173), Expect = 5e-11
Identities = 37/143 (25%), Positives = 79/143 (55%), Gaps = 16/143 (11%)
Query: 147 IITTILVNCILMIMPTTPTVES--------TEVIFTGIYTFESAVKVMARGFILQPFTYL 198
II I++N + + + T+P V + + + GI+ E +++ A G +
Sbjct: 53 IIGVIVLNAVTLGLETSPAVMAEVGGFLRLVDQVILGIFVIELMLRLYAHGL-----KFF 107
Query: 199 RDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKN 258
+D W+ DF ++A++ + GNL+ LR+ R+LRAL+ +++VP L+ ++G ++ ++
Sbjct: 108 KDPWSLFDFSIVAISLMPA---TGNLSVLRSLRILRALRLISVVPSLRRVIGGLVAALPG 164
Query: 259 LRDVIILTMFSLSVFALMGLQIY 281
+ +++L VFA+M ++Y
Sbjct: 165 MGSIVVLMALVFYVFAVMATKLY 187
Score = 72.5 bits (170), Expect = 1e-10
Identities = 49/180 (27%), Positives = 94/180 (52%), Gaps = 12/180 (6%)
Query: 1190 PFLAGDDDSPFWQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQ 1249
P G + P +G ++R + L+ + +E +I +I+L+++ L LE +
Sbjct: 20 PVHCGTHEKPSNRGT-SMRNQVRALVTSRNWEACIIGVIVLNAVTLGLETSPAVMAEV-G 77
Query: 1250 DILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGI 1309
L +D++ IF IE++++ A G K+F + W DF IV +SL+ L
Sbjct: 78 GFLRLVDQVILGIFVIELMLRLYAHGL-KFFKDPWSLFDFSIVAISLMPATGNL------ 130
Query: 1310 QAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
+R+LR LR LR +S + +R V+ LV A+P + +++++ + + +FA+M +L+
Sbjct: 131 ---SVLRSLRILRALRLISVVPSLRRVIGGLVAALPGMGSIVVLMALVFYVFAVMATKLY 187
Score = 66.5 bits (155), Expect = 7e-09
Identities = 48/191 (25%), Positives = 90/191 (47%), Gaps = 20/191 (10%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQ-SETFSAVLDYLNMIFIVIFSSECLLKIFAL 1590
+VT + ++ I+ I LN +T+ L+ L ++ + + IF E +L+++A
Sbjct: 43 LVTSRNWEACIIGVIVLNAVTLGLETSPAVMAEVGGFLRLVDQVILGIFVIELMLRLYAH 102
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
+F +PW+LFDF +V S++ + L V+R ++ R LRL+
Sbjct: 103 GLKFFKDPWSLFDFSIVAISLMPATGN------------LSVLRSLRILRALRLISVVPS 150
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMI 1710
+R ++ L +LP + +I +L+ LV ++FA+ + + F T S+
Sbjct: 151 LRRVIGGLVAALPGMGSIVVLMALVFYVFAVMATKLYGEAFPEW-------FGTLGASLY 203
Query: 1711 LLFQMSTSAGW 1721
LFQ+ T W
Sbjct: 204 TLFQVMTLESW 214
Score = 37.5 bits (83), Expect = 3.7
Identities = 15/62 (24%), Positives = 36/62 (58%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+S LR +L P+L +I + + +G++ ++ ++ ++FAVM +L+G+ +
Sbjct: 133 LRSLRILRALRLISVVPSLRRVIGGLVAALPGMGSIVVLMALVFYVFAVMATKLYGEAFP 192
Query: 887 DY 888
++
Sbjct: 193 EW 194
>UniRef50_Q22YT3 Cluster: Cation channel family protein; n=1;
Tetrahymena thermophila SB210|Rep: Cation channel family
protein - Tetrahymena thermophila SB210
Length = 1882
Score = 73.7 bits (173), Expect = 5e-11
Identities = 66/308 (21%), Positives = 134/308 (43%), Gaps = 13/308 (4%)
Query: 1216 ENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALG 1275
E++ F+ ++ I++ + L + L + I +DI+ ++ IF ++ I + G
Sbjct: 1240 ESSKFDFLMVLTIIVFAGILVWDSPFLNPKSIQKDIINISYKVLAGIFLFQLFIHLVQHG 1299
Query: 1276 F-----QKYFTNAWCW-LDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSR 1329
F + Y + LDF+ + L+ ++ + FK + R + L +S+
Sbjct: 1300 FLFNGPRSYLRRSLLSILDFVTTLAVLL-YILNITSKSNF-VFKCIAIFRVIFLLAFLSK 1357
Query: 1330 MQGMRVVVNALVQAIPS-IFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEI 1388
L+ S +F +++ +I+ L+ I+ +L + C + + + SH+I
Sbjct: 1358 YNKDIAFAGRLMAYCSSRMFKLIMFAMIYLLMNGIIATKLLKDSGWMCKHLYYPS-SHDI 1416
Query: 1389 IPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRE 1448
I K+ C W S NF+ + + LF V +GW+QIM D DS Q +
Sbjct: 1417 I-SKHDCFDLGGDWIESAYNFNSIIDSLQVLFMVQASEGWLQIMLDTFDSNSSQFQISYK 1475
Query: 1449 TNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYNAMKK 1508
++ LN+F+G+I+++ E + G+ +T+ QK+++ K
Sbjct: 1476 QQSIWAIFYIQYFFIANICILNMFVGLIVESLLELNEHESGTHS--LTKQQKEWFFIKKS 1533
Query: 1509 MGSKKPLK 1516
+ P+K
Sbjct: 1534 IRKLIPIK 1541
Score = 59.3 bits (137), Expect = 1e-06
Identities = 48/218 (22%), Positives = 101/218 (46%), Gaps = 24/218 (11%)
Query: 1667 NICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDV-YNFKTFVQSMILLFQMSTSAGWDGVL 1725
N+ +L+FL + + ++ F ++K + +++ NF F Q++ ++ T W +
Sbjct: 1549 NMMVLIFL--YTAVLLSLNLFPYLKFQSTINEYDLNFSGFFQALFSFIRIVTLEMWYLIP 1606
Query: 1726 ---------DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVI 1776
+ + ++ D D + +CGS + + + +L+ + LI++N+++A I
Sbjct: 1607 FEASQKMAPNFVCRDDMYDYYDFVKYGFQSCGSVISYLFFYVFFLIFT-LIILNLFVATI 1665
Query: 1777 LENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVL--------EP 1828
+E+Y +A + + D ++W +FDP G YI Y + F + E
Sbjct: 1666 IESYKEAFSADESAINHYQLDDILKLWTKFDPQGKGYISYKEFWQFSSQIAIVYGVNSEE 1725
Query: 1829 PLQIHKPNKYKIISMDIPICRG--DMMFCVDILDALTK 1864
L I +++ + S++IPI D +FC D + K
Sbjct: 1726 FLDIENKSQF-LKSLNIPIYEDPIDKIFCYKFHDVVEK 1762
Score = 49.2 bits (112), Expect = 0.001
Identities = 53/224 (23%), Positives = 98/224 (43%), Gaps = 22/224 (9%)
Query: 1224 VITMILLSSLALALEDVHLPHRPILQD---ILYYMDRIFTVIFFIEMLIKWLALGFQKYF 1280
+I I +L L + ++ L + I Q IL +D +I F E++ + +GFQK+F
Sbjct: 590 IIKAIFFLNLLLQIANLCLDNHWISQKAYIILNKIDFATIIILFCEIIYMIVFIGFQKFF 649
Query: 1281 TNAWCWLDFIIVMVSLINFVAALCGAGG-------IQAFKTMRTLRALRPLRAM---SRM 1330
+ + +D ++ + L +++ G G +Q F +R + R +
Sbjct: 650 KDVFNCVDCLVFLAHLTSYIYE--GVNGYDIFNPTLQMFILIRCTKVFRIFKIFFHYELF 707
Query: 1331 QGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHT-TLSHEII 1389
Q M V++ Q + SI ++V I ++FA +G +LFA Y + D +H ++ +
Sbjct: 708 QNMTVILKTYQQTLNSIPEYIIVFCILVILFAQIGRELFA--YSQPHDDHHVLRVNFNTL 765
Query: 1390 PDKNACTL---ENYTWENSPMNF-DHVGKAYLCLFQVATFKGWI 1429
D + N W S NF VG + + + GW+
Sbjct: 766 QDSLLAVVLIFYNEEWHISMYNFMRFVGYQSVIYYLICMLIGWV 809
Score = 38.7 bits (86), Expect = 1.6
Identities = 31/135 (22%), Positives = 59/135 (43%), Gaps = 10/135 (7%)
Query: 815 DHHNMDKDMDKALKSGNYLRVFKLA---KSWPTLNLLISIMGRTMGALGNLTFVLCIIIF 871
D N M ++ R+FK+ + + + +++ +T+ ++ V CI++
Sbjct: 677 DIFNPTLQMFILIRCTKVFRIFKIFFHYELFQNMTVILKTYQQTLNSIPEYIIVFCILVI 736
Query: 872 IFAVMGMQLFGKNYVDYVDRFPDGDLPRWNFTDFMHSFMIVFRVLCG-EWIESMWDCM-L 929
+FA +G +LF Y D + R NF S + V + EW SM++ M
Sbjct: 737 LFAQIGRELFA-----YSQPHDDHHVLRVNFNTLQDSLLAVVLIFYNEEWHISMYNFMRF 791
Query: 930 VGDVSCIPFFLATVV 944
VG S I + + ++
Sbjct: 792 VGYQSVIYYLICMLI 806
Score = 37.1 bits (82), Expect = 4.9
Identities = 20/96 (20%), Positives = 45/96 (46%), Gaps = 9/96 (9%)
Query: 1692 DKGG--LDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGS 1749
D GG ++ YNF + + S+ +LF + S GW ++ + + +
Sbjct: 1424 DLGGDWIESAYNFNSIIDSLQVLFMVQASEGWLQIMLDTFDSNSSQFQISYK-------Q 1476
Query: 1750 ATIGITYLLSYLVISFLIVINMYIAVILENYSQATE 1785
+I + + Y I+ + ++NM++ +I+E+ + E
Sbjct: 1477 QSIWAIFYIQYFFIANICILNMFVGLIVESLLELNE 1512
Score = 36.3 bits (80), Expect = 8.5
Identities = 34/188 (18%), Positives = 83/188 (44%), Gaps = 7/188 (3%)
Query: 1541 IIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPW 1599
I L + L + + LD++ S+ +L+ ++ I+I E + I + + +F + +
Sbjct: 594 IFFLNLLLQIANLCLDNHWISQKAYIILNKIDFATIIILFCEIIYMIVFIGFQKFFKDVF 653
Query: 1600 NLFDFVVVMFSILSLVLSDIIEKYFVSPTL--LRVVRVAKVGRVLRL---VKGAKGIRTL 1654
N D +V + + S + + +PTL ++R KV R+ ++ + + + +
Sbjct: 654 NCVDCLVFLAHLTSYIYEGVNGYDIFNPTLQMFILIRCTKVFRIFKIFFHYELFQNMTVI 713
Query: 1655 LFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDV-YNFKTFVQSMILLF 1713
L +L ++ ++ +++ +FA G F + + + NF T S++ +
Sbjct: 714 LKTYQQTLNSIPEYIIVFCILVILFAQIGRELFAYSQPHDDHHVLRVNFNTLQDSLLAVV 773
Query: 1714 QMSTSAGW 1721
+ + W
Sbjct: 774 LIFYNEEW 781
>UniRef50_A7S9M8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 748
Score = 73.7 bits (173), Expect = 5e-11
Identities = 43/147 (29%), Positives = 81/147 (55%), Gaps = 7/147 (4%)
Query: 1213 KLIENTYFETAVITMILLSSLALALE-DVHLPHRPILQDILYYMDRIFTVIFFIEMLIKW 1271
+ + N F T+++ +IL +SL + +E D L + + +D+ IF E+ +KW
Sbjct: 393 QFLSNKVFRTSILAVILFNSLLIVVETDQDLERQ--YSHLFAVLDQCIMTIFVCEIFVKW 450
Query: 1272 LALGFQKYFTNAWCWLDFIIVMVSLIN-FVAALCGAGGIQAFKTMRTLRALRPLRAMSRM 1330
GF ++ W LDF IV+ L+ ++ G+ G+ + +R LRA R LR++S +
Sbjct: 451 YH-GFFMFWKMGWNVLDFFIVVALLLGPLLSTDSGSRGV--LRILRVLRAFRSLRSISSL 507
Query: 1331 QGMRVVVNALVQAIPSIFNVLLVCLIF 1357
G+++VV ++Q+IP + + L + +F
Sbjct: 508 PGLQIVVRTILQSIPGLDSALAMFSLF 534
Score = 54.8 bits (126), Expect = 2e-05
Identities = 39/168 (23%), Positives = 80/168 (47%), Gaps = 5/168 (2%)
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSET-FSAVLDYLNMIFIVIFSSECLLK 1586
+V + +++K F I+ I N L + ++ Q E +S + L+ + IF E +K
Sbjct: 390 LVGQFLSNKVFRTSILAVILFNSLLIVVETDQDLERQYSHLFAVLDQCIMTIFVCEIFVK 449
Query: 1587 IFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVK 1646
+ + ++ WN+ DF F +++L+L ++ S +LR++RV + R LR +
Sbjct: 450 WYHGFFMFWKMGWNVLDF----FIVVALLLGPLLSTDSGSRGVLRILRVLRAFRSLRSIS 505
Query: 1647 GAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKG 1694
G++ ++ + S+P L + + L + + M F + KG
Sbjct: 506 SLPGLQIVVRTILQSIPGLDSALAMFSLFVCLTQDGWMEIFSEFRSKG 553
Score = 51.2 bits (117), Expect = 3e-04
Identities = 48/149 (32%), Positives = 75/149 (50%), Gaps = 22/149 (14%)
Query: 138 LVHPLFSLFIITTILVNCILMIMPTTPTVEST---------EVIFTGIYTFESAVKVMAR 188
L + +F I+ IL N +L+++ T +E + I T I+ E VK
Sbjct: 395 LSNKVFRTSILAVILFNSLLIVVETDQDLERQYSHLFAVLDQCIMT-IFVCEIFVK-WYH 452
Query: 189 GFILQPFTYLRDAWNWLD-FVVIALAY-VTMGIDLGNLAALRTFRVLRA---LKTVAIVP 243
GF F + + WN LD F+V+AL + D G+ LR RVLRA L++++ +P
Sbjct: 453 GF----FMFWKMGWNVLDFFIVVALLLGPLLSTDSGSRGVLRILRVLRAFRSLRSISSLP 508
Query: 244 GLKTIVGAVIESVKNLRDVIILTMFSLSV 272
GL+ +V +++S+ L L MFSL V
Sbjct: 509 GLQIVVRTILQSIPGLDSA--LAMFSLFV 535
>UniRef50_Q22YS7 Cluster: Cation channel family protein; n=1;
Tetrahymena thermophila SB210|Rep: Cation channel family
protein - Tetrahymena thermophila SB210
Length = 1921
Score = 73.3 bits (172), Expect = 6e-11
Identities = 45/198 (22%), Positives = 97/198 (48%), Gaps = 11/198 (5%)
Query: 1629 LLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
+LR+ ++ +V R++ K ++ LL + ++ +F + L+FL +++ + M+ F
Sbjct: 1377 ILRIAWSLQLIKVYRILAHLKVLKKLLNSFFGAVSNIFGLSTLVFLFLYVSVLLAMNLFP 1436
Query: 1689 HVKDKGGLDDV-YNFKTFVQSMILLFQMSTSAGWDGVLDG---------IINEEECDLPD 1738
++K++ +DD NF +F+ S++ L ++STS W + + ++ D
Sbjct: 1437 YIKNQNTIDDYDTNFNSFMMSLLTLIRISTSELWFPITAECAAQQSSVFVCRQDIYTYDD 1496
Query: 1739 NERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDM 1798
+ +CGS + + Y V + L ++N+ IA I+ +Y + + + D
Sbjct: 1497 YLKYGKNSCGSNLSYFFFNIYYFVFT-LFILNLLIASIILSYKEGYIQEESAINLYQLDD 1555
Query: 1799 YYEIWQRFDPDGSQYIRY 1816
++W FDP+G +I Y
Sbjct: 1556 IKKLWSNFDPEGHGFINY 1573
Score = 58.0 bits (134), Expect = 2e-06
Identities = 53/237 (22%), Positives = 98/237 (41%), Gaps = 14/237 (5%)
Query: 1387 EIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPI 1446
E++ DK+ C W F++V + L V T +GW QIM + QP
Sbjct: 1191 EVVTDKD-CMDVGGDWVEYKYQFNNVFSSIAVLLMVQTSEGWTQIMEQQFNYTSPNTQPK 1249
Query: 1447 RETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKYYN-- 1504
+E + L+ LN+F+GV++D F E K+ L+ +T QK++Y
Sbjct: 1250 KEHQSFWILFYIQFYCIANFCILNMFVGVVVDTFKELKENE-AKLDK-LTPQQKEWYYIK 1307
Query: 1505 ------AMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKF-DMIIMLFIGLNMLT-MTLD 1556
++ K + I P + + ++E + +KK+ + F LN + +
Sbjct: 1308 YSIYSLSISKKSTCTFKHQITPPEDKISSFIYETLEEKKYLKYLFNFFTVLNCASILGYT 1367
Query: 1557 HYQQSETFSAVLDYLNMIFIVIFSSECLLKIF-ALRYHYFVEPWNLFDFVVVMFSIL 1612
H Q + + + ++ I ++ LK+ L +F N+F ++F L
Sbjct: 1368 HRQDEQKLNILRIAWSLQLIKVYRILAHLKVLKKLLNSFFGAVSNIFGLSTLVFLFL 1424
Score = 42.7 bits (96), Expect = 0.098
Identities = 41/181 (22%), Positives = 86/181 (47%), Gaps = 11/181 (6%)
Query: 1211 TFKLIENTYFETAVI-TMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLI 1269
+ K I+N+ + T I L + L+L+ V + + ILY +D I T+I F+E+ I
Sbjct: 498 SLKQIQNSSIYVIIRHTNICLQIVVLSLDRVSIKDDQL--SILYIIDFITTLILFLEITI 555
Query: 1270 KWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSR 1329
+ ++ G++KY+ LD I + +I + I F T + +R ++
Sbjct: 556 ELISFGWKKYWKEQLNKLDLCIALAHIIMYCIETNNQLDI-FFATNQYSIFIRTTKS--- 611
Query: 1330 MQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGK-YFKCVDMNHTTLSHEI 1388
++V++ + + I +V I ++A++G +LF+ + + + +N +LS
Sbjct: 612 ---IKVILKTYSKTLKMITGYFIVISILITLYALIGRELFSQRVQYDDMMINFNSLSDSF 668
Query: 1389 I 1389
+
Sbjct: 669 L 669
>UniRef50_Q22YS9 Cluster: Cation channel family protein; n=1;
Tetrahymena thermophila SB210|Rep: Cation channel family
protein - Tetrahymena thermophila SB210
Length = 1739
Score = 72.9 bits (171), Expect = 8e-11
Identities = 61/278 (21%), Positives = 134/278 (48%), Gaps = 18/278 (6%)
Query: 1562 ETFSAVLDYLNMIFIVIFSSE--CLLK--IFALRYHYFVEPWNLFDFVVVMFSILSL--V 1615
E+FS +L+ N+I + + +K I+A++ + + NLF+ V++ L+L
Sbjct: 1366 ESFSELLEKENLIHTLNPQQKEWYFIKSSIYAIQRQFLISKKNLFNLTVIIIGWLNLSFQ 1425
Query: 1616 LSDIIEKYFVSPTLL-RVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFL 1674
L++ ++ Y + +L + + ++ R + + IR L +L ++ ++ + +++ +
Sbjct: 1426 LNNDVKTYNFNYRILDGIAKGLQLIRAYIIFRHFVLIRKLFKSLHYAISSIKGVLIIVVV 1485
Query: 1675 VMFIFAIFGMSFFMHVKDKGGLDDVYN-FKTFVQSMILLFQMSTSAGWDGVLDGIINEEE 1733
++ + ++ F ++K + ++ N F+TF Q+ L ++ TS W + ++E
Sbjct: 1486 FLYTSVLLSLNLFPYLKPQEIINYYDNHFQTFFQATFTLIRIVTSEAWYLIPLECSQKQE 1545
Query: 1734 ----C-----DLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYSQAT 1784
C D + +CG++ + YL + L+++N++IA I+E+Y Q+
Sbjct: 1546 PNFVCRNDMHSYEDYVQFGLASCGNSLSFFFFYFFYLFFT-LVILNIFIATIIESYKQSF 1604
Query: 1785 EDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRYDQLSDF 1822
+ + + D E+W FDP G YI Y Q F
Sbjct: 1605 KADESAINHYQMDDILELWTAFDPQGKGYITYKQFWKF 1642
Score = 58.8 bits (136), Expect = 1e-06
Identities = 42/195 (21%), Positives = 86/195 (44%), Gaps = 6/195 (3%)
Query: 1313 KTMRTLRALRPLRAMSRMQGMRVVVNALVQ-AIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
K + R L L +++ LVQ P + ++ +++ L+ I+ +L G
Sbjct: 1197 KLINIFRLLLVLIYLAKYNQQIKFAGKLVQECAPRMKKLITFTVLYLLMMGIITTKLLKG 1256
Query: 1372 KYFKCVD---MNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGW 1428
+ ++C E++ K C W S N+D++ K+ L+ + + +GW
Sbjct: 1257 QNWQCTFPTVYGEDKGYQELVVSKTDCIDLGGDWTESDYNYDNIIKSVQILYNIQSSEGW 1316
Query: 1429 IQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKAG 1488
QIM D DS+ + + Y ++ LN+F+G+++++F+E +K
Sbjct: 1317 SQIMFDTYDSQGRNLTHQYQAHSYWAIFFIQFYFIAFVCFLNMFVGLMVESFSELLEKE- 1375
Query: 1489 GSLEMFMTEDQKKYY 1503
+L + QK++Y
Sbjct: 1376 -NLIHTLNPQQKEWY 1389
>UniRef50_Q0F227 Cluster: Ion transport protein; n=1; Mariprofundus
ferrooxydans PV-1|Rep: Ion transport protein -
Mariprofundus ferrooxydans PV-1
Length = 256
Score = 72.5 bits (170), Expect = 1e-10
Identities = 62/254 (24%), Positives = 117/254 (46%), Gaps = 43/254 (16%)
Query: 1540 MIIMLFIGLNMLTMTLDHYQQSETFSAV----LDYLNMIFIVIFSSECLLKIFALRYH-- 1593
M IG+ +L+ L + SE A + + N + + IF E LKI+A+
Sbjct: 1 MFEYFIIGIILLSAVLIGLETSEEMLADYGHWITWGNRLVLGIFIIEAALKIYAVAPRLK 60
Query: 1594 -YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIR 1652
YF WNLFDF +++ ++L + L + R+A++ RVLRL+ +R
Sbjct: 61 LYFGSGWNLFDFTIIVLALLPS-----------TGELAMLARLARLLRVLRLITAIPELR 109
Query: 1653 TLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILL 1712
++ L S+P++ NI LL+ ++ +I+A+ G F D +++ S++ L
Sbjct: 110 LIVATLMRSIPSMGNIMLLMGVIFYIYAVAGQQLFHE-------HDPVHWRNLGISLLTL 162
Query: 1713 FQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMY 1772
F++ T W V+ + Y +S++V+ ++IN++
Sbjct: 163 FRIVTLEDWTDVMYTAMEMN------------------VYSWIYFVSFVVLGTFVIINLF 204
Query: 1773 IAVILENYSQATED 1786
IAV++ N +A ++
Sbjct: 205 IAVVINNLEEAKQE 218
Score = 62.9 bits (146), Expect = 9e-08
Identities = 46/155 (29%), Positives = 83/155 (53%), Gaps = 17/155 (10%)
Query: 1220 FETAVITMILLSSLALALEDVHLPHRPILQDILYYM---DRIFTVIFFIEMLIKWLALG- 1275
FE +I +ILLS++ + LE +L D +++ +R+ IF IE +K A+
Sbjct: 2 FEYFIIGIILLSAVLIGLET----SEEMLADYGHWITWGNRLVLGIFIIEAALKIYAVAP 57
Query: 1276 -FQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMR 1334
+ YF + W DF I++++L+ L R R LR LR ++ + +R
Sbjct: 58 RLKLYFGSGWNLFDFTIIVLALLPSTGELA--------MLARLARLLRVLRLITAIPELR 109
Query: 1335 VVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
++V L+++IPS+ N++L+ + + I+A+ G QLF
Sbjct: 110 LIVATLMRSIPSMGNIMLLMGVIFYIYAVAGQQLF 144
Score = 60.5 bits (140), Expect = 5e-07
Identities = 40/148 (27%), Positives = 77/148 (52%), Gaps = 12/148 (8%)
Query: 142 LFSLFIITTILVNCILMIMPTTPTVEST--------EVIFTGIYTFESAVKVMARGFILQ 193
+F FII IL++ +L+ + T+ + + + GI+ E+A+K+ A L+
Sbjct: 1 MFEYFIIGIILLSAVLIGLETSEEMLADYGHWITWGNRLVLGIFIIEAALKIYAVAPRLK 60
Query: 194 PFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVI 253
Y WN DF +I LA + +L LA R R+LR L+ + +P L+ IV ++
Sbjct: 61 --LYFGSGWNLFDFTIIVLALLPSTGELAMLA--RLARLLRVLRLITAIPELRLIVATLM 116
Query: 254 ESVKNLRDVIILTMFSLSVFALMGLQIY 281
S+ ++ ++++L ++A+ G Q++
Sbjct: 117 RSIPSMGNIMLLMGVIFYIYAVAGQQLF 144
Score = 44.8 bits (101), Expect = 0.024
Identities = 32/114 (28%), Positives = 62/114 (54%), Gaps = 15/114 (13%)
Query: 833 LRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRF 892
LRV +L + P L L+++ + R++ ++GN+ ++ +I +I+AV G QLF ++
Sbjct: 96 LRVLRLITAIPELRLIVATLMRSIPSMGNIMLLMGVIFYIYAVAGQQLFHEH-------- 147
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCMLVGDVSCIPFFLATVVI 945
D W + S + +FR++ E W + M+ M + S I +F++ VV+
Sbjct: 148 ---DPVHWR--NLGISLLTLFRIVTLEDWTDVMYTAMEMNVYSWI-YFVSFVVL 195
>UniRef50_Q47UV3 Cluster: Cation channel family protein; n=2;
Colwellia psychrerythraea|Rep: Cation channel family
protein - Colwellia psychrerythraea (strain 34H / ATCC
BAA-681) (Vibriopsychroerythus)
Length = 271
Score = 72.1 bits (169), Expect = 1e-10
Identities = 48/160 (30%), Positives = 86/160 (53%), Gaps = 12/160 (7%)
Query: 1210 KTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLI 1269
K + +E+ F++ +I +IL ++++L LE ++L+ +D V+F IE+L+
Sbjct: 9 KLQRFVESKKFQSFLIFLILFNAISLGLETSQFGKANA--ELLHTIDTTILVLFTIELLL 66
Query: 1270 KWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSR 1329
K++ Q +F + W W DFIIV +S A G A +R R LR LR +S
Sbjct: 67 KFIVYRNQ-FFRSGWNWFDFIIVAISW----APTSG-----ALSVLRAFRILRVLRLLSV 116
Query: 1330 MQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
+ MR V+ AL ++P + +V+ V I + + A++ ++F
Sbjct: 117 VPQMRRVIGALGHSLPGMASVVGVLSIIFYVSAVLTTKIF 156
Score = 67.7 bits (158), Expect = 3e-09
Identities = 49/189 (25%), Positives = 86/189 (45%), Gaps = 15/189 (7%)
Query: 1533 VTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRY 1592
V KKF ++ I N +++ L+ Q + + +L ++ +V+F+ E LLK R
Sbjct: 14 VESKKFQSFLIFLILFNAISLGLETSQFGKANAELLHTIDTTILVLFTIELLLKFIVYRN 73
Query: 1593 HYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIR 1652
+F WN FDF++V S + + L V+R ++ RVLRL+ +R
Sbjct: 74 QFFRSGWNWFDFIIVAIS------------WAPTSGALSVLRAFRILRVLRLLSVVPQMR 121
Query: 1653 TLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILL 1712
++ AL SLP + ++ +L ++ ++ A+ F D + F S L
Sbjct: 122 RVIGALGHSLPGMASVVGVLSIIFYVSAVLTTKIFGTHSDANMQE---WFGNIGASAYTL 178
Query: 1713 FQMSTSAGW 1721
FQ+ T W
Sbjct: 179 FQVMTLESW 187
Score = 66.1 bits (154), Expect = 9e-09
Identities = 37/144 (25%), Positives = 77/144 (53%), Gaps = 11/144 (7%)
Query: 143 FSLFIITTILVNCILMIMPTTPTVESTEVIFTGIYTFESAVKVMAR-----GFILQPFTY 197
F F+I IL N I + + T+ ++ + ++T ++ + V+ FI+ +
Sbjct: 19 FQSFLIFLILFNAISLGLETSQFGKANAEL---LHTIDTTILVLFTIELLLKFIVYRNQF 75
Query: 198 LRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVK 257
R WNW DF+++A+++ G L+ LR FR+LR L+ +++VP ++ ++GA+ S+
Sbjct: 76 FRSGWNWFDFIIVAISWAPTS---GALSVLRAFRILRVLRLLSVVPQMRRVIGALGHSLP 132
Query: 258 NLRDVIILTMFSLSVFALMGLQIY 281
+ V+ + V A++ +I+
Sbjct: 133 GMASVVGVLSIIFYVSAVLTTKIF 156
>UniRef50_UPI0000F2E29A Cluster: PREDICTED: similar to sperm ion
channel; n=1; Monodelphis domestica|Rep: PREDICTED:
similar to sperm ion channel - Monodelphis domestica
Length = 478
Score = 71.7 bits (168), Expect = 2e-10
Identities = 79/325 (24%), Positives = 138/325 (42%), Gaps = 43/325 (13%)
Query: 1482 EQKKKAGGSLEMFMTEDQKKYYNAMKK---MGS--KKPLKAIPRPRWRPQAIVFEIVTDK 1536
EQ+KK+ +M K KK +G KK I + R Q ++ ++
Sbjct: 76 EQEKKSKHKCKMNSRGLPAKMQRGQKKHMTIGDLLKKFCSEIHKICVRIQDMLLVLIKSN 135
Query: 1537 KFDMIIMLFIGLNMLTMTLDHYQQSETFSA-VLDYLNMIFIVIFSSECLLKIFALRYHYF 1595
F+ I + + LN L + + + + E + L+ +F+ I+ E +LKI YF
Sbjct: 136 YFESFIFIVVCLNTLLLVIQTFAEVEIWGEWYFAVLDSVFLCIYFMEAVLKILVFGLGYF 195
Query: 1596 VEPWNLFDFVVVMFSILSLVLSDI----IEKYFVSPTLLRVVRVAKVGRVLRLV------ 1645
WN DF +V+ ++L VL I ++ S T+ RV+++ K R LR +
Sbjct: 196 -HKWNNLDFAIVIMALLDFVLKQIYFSSAKRLSESKTIFRVLKIFKSFRSLRAIRVLWKL 254
Query: 1646 KGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTF 1705
K ++ + LA S ++ I +L+F +F F++ + F +D +F
Sbjct: 255 KFLTSLKGVAETLARSASSITAILVLMFTCLFFFSVMLRALFHE-------EDPKHFGNI 307
Query: 1706 VQSMILLFQMSTSAGWD-GVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVIS 1764
++ LF M T W LD +P L+ Y+VI
Sbjct: 308 FITIFTLFTMLTLDDWSMTFLDKRTTNSWYIIP------------------ILMIYIVIQ 349
Query: 1765 FLIVINMYIAVILENYSQATEDVQE 1789
+LI +N+ IAV+++N+ + QE
Sbjct: 350 YLIFLNLVIAVLVDNFQIVLRNKQE 374
Score = 55.6 bits (128), Expect = 1e-05
Identities = 45/170 (26%), Positives = 85/170 (50%), Gaps = 18/170 (10%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILY-YMDRIFTVIFFIEMLIKWL 1272
LI++ YFE+ + ++ L++L L ++ I + + +D +F I+F+E ++K L
Sbjct: 131 LIKSNYFESFIFIVVCLNTLLLVIQT--FAEVEIWGEWYFAVLDSVFLCIYFMEAVLKIL 188
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGG-------------IQAFKTMRTLR 1319
G YF + W LDF IV+++L++FV ++ FK+ R+LR
Sbjct: 189 VFGLG-YF-HKWNNLDFAIVIMALLDFVLKQIYFSSAKRLSESKTIFRVLKIFKSFRSLR 246
Query: 1320 ALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
A+R L + + ++ V L ++ SI +L++ F++M LF
Sbjct: 247 AIRVLWKLKFLTSLKGVAETLARSASSITAILVLMFTCLFFFSVMLRALF 296
>UniRef50_Q22BI8 Cluster: Cation channel family protein; n=1;
Tetrahymena thermophila SB210|Rep: Cation channel family
protein - Tetrahymena thermophila SB210
Length = 1129
Score = 71.7 bits (168), Expect = 2e-10
Identities = 49/212 (23%), Positives = 98/212 (46%), Gaps = 24/212 (11%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFV 1596
FD+ ++L + +N + + +++ +++D ++ F + E L+K+ + YF
Sbjct: 81 FDVSMLLILIINCAILFISMTSDNQSTQSLMDQIDDYFFYAYLLEFLIKVIGIGIEKYFE 140
Query: 1597 EPWNLFDFVVVMFSILSLVLSDIIE--KYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTL 1654
+ WN FDF +V+ S L++VLS + + S +++R+ K+ RV R+ K + I+ L
Sbjct: 141 DSWNCFDFFMVVMSFLNIVLSTTLSFLQNTKSAKATKLLRLTKINRVFRIFKALRSIKFL 200
Query: 1655 LFALA----------------MSLPALFNICLLLFLVMFIFAIFGMSFF----MHVKDKG 1694
LA M LP + + ++ +V +I+ G+ F +
Sbjct: 201 SILLAGFELFYQVKDLLIKIFMCLPIVVRLIPIILVVYYIYTYIGLDNFNTNTFNYNQNS 260
Query: 1695 GLDDVY-NFKTFVQSMILLFQMSTSAGWDGVL 1725
D Y +F F +M++ FQ+ A W +
Sbjct: 261 PYDQGYADFNNFYGAMLIYFQIMIEANWSSYI 292
Score = 47.6 bits (108), Expect = 0.003
Identities = 25/110 (22%), Positives = 56/110 (50%), Gaps = 3/110 (2%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
K+ + F+ +++ +++++ L + Q ++ +D F + +E LIK +
Sbjct: 74 KIARSPIFDVSMLLILIINCAILFISMTS--DNQSTQSLMDQIDDYFFYAYLLEFLIKVI 131
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALR 1322
+G +KYF ++W DF +V++S +N V + +Q K+ + + LR
Sbjct: 132 GIGIEKYFEDSWNCFDFFMVVMSFLNIVLSTT-LSFLQNTKSAKATKLLR 180
Score = 41.1 bits (92), Expect = 0.30
Identities = 29/134 (21%), Positives = 63/134 (47%), Gaps = 17/134 (12%)
Query: 141 PLFSLFIITTILVNCILMIMPTTPTVESTEVIFTGI-------YTFESAVKVMARGFILQ 193
P+F + ++ +++NC ++ + T +ST+ + I Y E +KV+ G
Sbjct: 79 PIFDVSMLLILIINCAILFISMTSDNQSTQSLMDQIDDYFFYAYLLEFLIKVIGIGI--- 135
Query: 194 PFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVI 253
Y D+WN DF ++ ++++ + + L+ L+ + +A K + + T + V
Sbjct: 136 -EKYFEDSWNCFDFFMVVMSFLNIVLST-TLSFLQNTKSAKATKLLRL-----TKINRVF 188
Query: 254 ESVKNLRDVIILTM 267
K LR + L++
Sbjct: 189 RIFKALRSIKFLSI 202
>UniRef50_A4GJA9 Cluster: Putative ion transport protein; n=1;
uncultured marine bacterium EB0_49D07|Rep: Putative ion
transport protein - uncultured marine bacterium EB0_49D07
Length = 246
Score = 70.9 bits (166), Expect = 3e-10
Identities = 51/202 (25%), Positives = 100/202 (49%), Gaps = 19/202 (9%)
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL 1590
++ K F I++ I + + + Y S ++ LD + + F E ++++ +
Sbjct: 10 KVRNSKAFSGIVIAVIVASAVYAGVSSYDISPEYTVYLDLFDYAITLFFLIEIIIRMISE 69
Query: 1591 R--YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGA 1648
R +F + WN+FDF++V +SLV + +E FV+ LLR++RV LR++
Sbjct: 70 RSLIKFFSDGWNIFDFLIVT---ISLVPINNVESVFVA-RLLRIIRV------LRIITVV 119
Query: 1649 KGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQS 1708
R ++ +L ++P + I LL+F+ M+++ G FF G D N+ +
Sbjct: 120 PAFRHIIDSLIKTIPRVGFIALLMFIFMYVWGAIGTMFF-------GKVDPENWGNIGLA 172
Query: 1709 MILLFQMSTSAGWDGVLDGIIN 1730
+I L Q++T W ++ +I+
Sbjct: 173 LITLVQVATYDDWANIMAQVID 194
Score = 59.3 bits (137), Expect = 1e-06
Identities = 38/159 (23%), Positives = 79/159 (49%), Gaps = 12/159 (7%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHL-PHRPILQDILYYMDRIFTVIFFIEMLIKW 1271
K+ + F VI +I+ S++ + + P + D+ Y T+ F IE++I+
Sbjct: 10 KVRNSKAFSGIVIAVIVASAVYAGVSSYDISPEYTVYLDLFDYA---ITLFFLIEIIIRM 66
Query: 1272 LA-LGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRM 1330
++ K+F++ W DF+IV +SL+ +++ R LR +R LR ++ +
Sbjct: 67 ISERSLIKFFSDGWNIFDFLIVTISLVPI-------NNVESVFVARLLRIIRVLRIITVV 119
Query: 1331 QGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
R ++++L++ IP + + L+ IF ++ +G F
Sbjct: 120 PAFRHIIDSLIKTIPRVGFIALLMFIFMYVWGAIGTMFF 158
Score = 48.4 bits (110), Expect = 0.002
Identities = 25/106 (23%), Positives = 58/106 (54%), Gaps = 11/106 (10%)
Query: 197 YLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESV 256
+ D WN DF+++ ++ V + ++ ++ R R++R L+ + +VP + I+ ++I+++
Sbjct: 75 FFSDGWNIFDFLIVTISLVPIN-NVESVFVARLLRIIRVLRIITVVPAFRHIIDSLIKTI 133
Query: 257 KNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNL 302
+ + +L + V+ +G ++ G KV PE +WGN+
Sbjct: 134 PRVGFIALLMFIFMYVWGAIG-TMFFG-------KVDPE--NWGNI 169
>UniRef50_Q0BXG6 Cluster: Cation channel family protein; n=2;
Hyphomonas neptunium|Rep: Cation channel family protein -
Hyphomonas neptunium (strain ATCC 15444)
Length = 287
Score = 70.1 bits (164), Expect = 6e-10
Identities = 50/192 (26%), Positives = 89/192 (46%), Gaps = 20/192 (10%)
Query: 1542 IMLFIGLNMLTMTLDHYQQS--ETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPW 1599
IM I +N + + + Y + A L +++M IF +E +LK++ R +F W
Sbjct: 28 IMALIVINAVVLGVLTYSEQLPAWLVAALTFIDMAVTFIFVAEIVLKLYVYRLQFFKLGW 87
Query: 1600 NLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALA 1659
N FDF+VV S++ + V+R +V R+LRL+ ++ + AL
Sbjct: 88 NWFDFMVVGVSVIP------------GGSTFNVLRALRVLRLLRLLHFIPTMKRITEALL 135
Query: 1660 MSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSA 1719
+LP + I +L LV ++ + F G + NF T S + +F++ T
Sbjct: 136 TALPGMGAILAILGLVFYVSVVMATYLF------SGSQNTENFSTLAASALTMFEVLTME 189
Query: 1720 GWDGVLDGIINE 1731
GW+G + ++ E
Sbjct: 190 GWNGHMRDLMEE 201
Score = 64.5 bits (150), Expect = 3e-08
Identities = 42/159 (26%), Positives = 77/159 (48%), Gaps = 10/159 (6%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
+ IE + ++ +I+++++ L + L L ++D T IF E+++K
Sbjct: 17 RFIERPFVRDTIMALIVINAVVLGVLTYSEQLPAWLVAALTFIDMAVTFIFVAEIVLKLY 76
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG 1332
Q +F W W DF++V VS+I GG F +R LR LR LR + +
Sbjct: 77 VYRLQ-FFKLGWNWFDFMVVGVSVI--------PGG-STFNVLRALRVLRLLRLLHFIPT 126
Query: 1333 MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
M+ + AL+ A+P + +L + + + + +M LF+G
Sbjct: 127 MKRITEALLTALPGMGAILAILGLVFYVSVVMATYLFSG 165
Score = 46.4 bits (105), Expect = 0.008
Identities = 23/106 (21%), Positives = 52/106 (49%), Gaps = 4/106 (3%)
Query: 178 TFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALK 237
TF +++ + ++ + + + WNW DF+V+ ++ + G LR RVLR L+
Sbjct: 64 TFIFVAEIVLKLYVYR-LQFFKLGWNWFDFMVVGVSVIPGG---STFNVLRALRVLRLLR 119
Query: 238 TVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
+ +P +K I A++ ++ + ++ + V +M ++ G
Sbjct: 120 LLHFIPTMKRITEALLTALPGMGAILAILGLVFYVSVVMATYLFSG 165
>UniRef50_Q7RTX7 Cluster: Cation channel sperm-associated protein 4;
n=15; Theria|Rep: Cation channel sperm-associated protein
4 - Homo sapiens (Human)
Length = 472
Score = 69.7 bits (163), Expect = 7e-10
Identities = 50/212 (23%), Positives = 103/212 (48%), Gaps = 12/212 (5%)
Query: 1213 KLIENTYFETAVITMILLSSLALALE-DVHLPHRPILQDILYYMDRIFTVIFFIEMLIKW 1271
+L+ + F+ + +++++++ +AL + +L + ++ +D I I E+L+ W
Sbjct: 87 QLLRHPAFQLLLALLLVINAITIALRTNSYLDQKHY--ELFSTIDDIVLTILLCEVLLGW 144
Query: 1272 LALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQ 1331
L GF ++ + W L+FIIV + L+ F I TLRALR + ++
Sbjct: 145 LN-GFWIFWKDGWNILNFIIVFILLLRFFINEINIPSINY-----TLRALRLVHVCMAVE 198
Query: 1332 GMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG---KYFKCVDMNHTTLSHEI 1388
+ ++ ++Q++P + N++++ L F L+F++ GV LF K+F+ + + TL I
Sbjct: 199 PLARIIRVILQSVPDMANIMVLILFFMLVFSVFGVTLFGAFVPKHFQNIQVALYTLFICI 258
Query: 1389 IPDKNACTLENYTWENSPMNFDHVGKAYLCLF 1420
D ++ E + G Y +F
Sbjct: 259 TQDGWVDIYSDFQTEKREYAMEIGGAIYFTIF 290
Score = 59.3 bits (137), Expect = 1e-06
Identities = 32/149 (21%), Positives = 79/149 (53%), Gaps = 4/149 (2%)
Query: 137 ILVHPLFSLFIITTILVNCILMIMPTTPTVESTEV-IFTGIYTFESAVKV--MARGFILQ 193
+L HP F L + +++N I + + T ++ +F+ I + + + G++
Sbjct: 88 LLRHPAFQLLLALLLVINAITIALRTNSYLDQKHYELFSTIDDIVLTILLCEVLLGWLNG 147
Query: 194 PFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALR-TFRVLRALKTVAIVPGLKTIVGAV 252
+ + +D WN L+F+++ + + I+ N+ ++ T R LR + V L I+ +
Sbjct: 148 FWIFWKDGWNILNFIIVFILLLRFFINEINIPSINYTLRALRLVHVCMAVEPLARIIRVI 207
Query: 253 IESVKNLRDVIILTMFSLSVFALMGLQIY 281
++SV ++ ++++L +F + VF++ G+ ++
Sbjct: 208 LQSVPDMANIMVLILFFMLVFSVFGVTLF 236
Score = 55.6 bits (128), Expect = 1e-05
Identities = 57/263 (21%), Positives = 114/263 (43%), Gaps = 32/263 (12%)
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTL--DHYQQSETFSAVLDYLNMIFIVIFSSECLLKIF 1588
+++ F +++ L + +N +T+ L + Y + + + ++ I + I E LL
Sbjct: 87 QLLRHPAFQLLLALLLVINAITIALRTNSYLDQKHYE-LFSTIDDIVLTILLCEVLLGWL 145
Query: 1589 ALRYHYFVEPWNLFDFVVVMFSILSLVLSDI-IEKYFVSPTLLRVVRVAKVGRVLRLVKG 1647
+ ++ + WN+ +F++V +L +++I I + LR+V V L
Sbjct: 146 NGFWIFWKDGWNILNFIIVFILLLRFFINEINIPSINYTLRALRLVHVCMAVEPL----- 200
Query: 1648 AKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQ 1707
A+ IR +L S+P + NI +L+ M +F++FG++ F K +F+
Sbjct: 201 ARIIRVIL----QSVPDMANIMVLILFFMLVFSVFGVTLFGAFVPK-------HFQNIQV 249
Query: 1708 SMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLI 1767
++ LF T GW + D +R G G Y ++ I I
Sbjct: 250 ALYTLFICITQDGWVDIYS--------DFQTEKREYAMEIG----GAIYFTIFITIGAFI 297
Query: 1768 VINMYIAVILENYSQATEDVQEG 1790
IN+++ V+ N Q + ++G
Sbjct: 298 GINLFVIVVTTNLEQMMKAGEQG 320
>UniRef50_UPI0001555295 Cluster: PREDICTED: similar to CatSper4,
partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
similar to CatSper4, partial - Ornithorhynchus anatinus
Length = 487
Score = 69.3 bits (162), Expect = 1e-09
Identities = 45/163 (27%), Positives = 91/163 (55%), Gaps = 12/163 (7%)
Query: 1213 KLIENTYFETAVITMILLSSLALALE-DVHLPHRPILQDILYYMDRIFTVIFFIEMLIKW 1271
+L+++ F+ + ++++++ +AL DV L R ++ +D I I F E+L+ W
Sbjct: 86 QLLQHPAFQALLAVLLVVNAFTIALRTDVSLSQRHY--ELFSALDDIVLTILFCEVLLGW 143
Query: 1272 LALGFQKYFTNAWCWLDFIIVM-VSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRM 1330
GF ++ + W L+FIIV+ +SL F ++ AF + TLR +R ++ +
Sbjct: 144 FN-GFWIFWKDGWNVLNFIIVLNLSLALFFDSMKS----NAF--LYTLRLVRLVQVCMAV 196
Query: 1331 QGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
+ + ++ +VQ++P + N++++ F L+F++ GV LF G Y
Sbjct: 197 EPLARIIRVIVQSVPDMVNIMVLIFFFMLVFSVFGVTLF-GNY 238
Score = 59.7 bits (138), Expect = 8e-07
Identities = 74/306 (24%), Positives = 136/306 (44%), Gaps = 36/306 (11%)
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTMTL-DHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFA 1589
+++ F ++ + + +N T+ L S+ + L+ I + I E LL F
Sbjct: 86 QLLQHPAFQALLAVLLVVNAFTIALRTDVSLSQRHYELFSALDDIVLTILFCEVLLGWFN 145
Query: 1590 LRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK 1649
+ ++ + WN+ +F++V+ L+L + F+ LR+VR+ +V + + A+
Sbjct: 146 GFWIFWKDGWNVLNFIIVLNLSLALFFDSMKSNAFLYT--LRLVRLVQVCMAVEPL--AR 201
Query: 1650 GIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSM 1709
IR ++ S+P + NI +L+F M +F++FG++ F + K +F+ ++
Sbjct: 202 IIRVIV----QSVPDMVNIMVLIFFFMLVFSVFGVTLFGNYMPK-------HFQNIQVAL 250
Query: 1710 ILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPG-NCGSATIGITYLLSYLVISFLIV 1768
LF T GW +D I NE + ERG GSA Y ++ + I
Sbjct: 251 YTLFICITQDGW---VD-IYNEFQM-----ERGQYSLQVGSA----LYFSIFITVGAFIG 297
Query: 1769 INMYIAVILENYSQATEDVQEGL--TDDDYDMYYEIWQRFDPDGSQYIRYDQLSDFLDVL 1826
N+ + V+ N Q + +QE L + + I D DG+ + QL DV
Sbjct: 298 TNLLVVVVTTNLEQMMK-MQETLLMQKQQQEQFANIEFSMDDDGAPEL---QLVHCKDVQ 353
Query: 1827 EPPLQI 1832
E Q+
Sbjct: 354 EESAQL 359
Score = 52.8 bits (121), Expect = 9e-05
Identities = 30/149 (20%), Positives = 75/149 (50%), Gaps = 4/149 (2%)
Query: 137 ILVHPLFSLFIITTILVNCILMIMPTTPTVESTEV-IFTGIYTFESAVKV--MARGFILQ 193
+L HP F + ++VN + + T ++ +F+ + + + G+
Sbjct: 87 LLQHPAFQALLAVLLVVNAFTIALRTDVSLSQRHYELFSALDDIVLTILFCEVLLGWFNG 146
Query: 194 PFTYLRDAWNWLDFVVIALAYVTMGID-LGNLAALRTFRVLRALKTVAIVPGLKTIVGAV 252
+ + +D WN L+F+++ + + D + + A L T R++R ++ V L I+ +
Sbjct: 147 FWIFWKDGWNVLNFIIVLNLSLALFFDSMKSNAFLYTLRLVRLVQVCMAVEPLARIIRVI 206
Query: 253 IESVKNLRDVIILTMFSLSVFALMGLQIY 281
++SV ++ ++++L F + VF++ G+ ++
Sbjct: 207 VQSVPDMVNIMVLIFFFMLVFSVFGVTLF 235
>UniRef50_UPI0000F1F6F8 Cluster: PREDICTED: hypothetical protein; n=1;
Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
rerio
Length = 656
Score = 69.3 bits (162), Expect = 1e-09
Identities = 41/160 (25%), Positives = 84/160 (52%), Gaps = 13/160 (8%)
Query: 1648 AKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMH-VKDK----GGLDDVYNF 1702
A G+R LL + +LP + N+ LL L+ FIFA G+ F + D+ GL F
Sbjct: 2 AVGMRALLDTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLICDELHPCEGLGRYATF 61
Query: 1703 KTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLV 1762
K F + +LLF++ST W+G++ + + D G C + + Y +S+++
Sbjct: 62 KNFGMAFLLLFRVSTGDNWNGIMKDTLRDCSQD--------TGICYNTVVSPIYFVSFVL 113
Query: 1763 ISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEI 1802
+ +++N+ IAV++++ ++ ++ +E + + ++ E+
Sbjct: 114 TAQFVLVNVVIAVLMKHLEESNKEAKEAEAEAELELEQEM 153
Score = 48.4 bits (110), Expect = 0.002
Identities = 42/158 (26%), Positives = 75/158 (47%), Gaps = 25/158 (15%)
Query: 1332 GMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPD 1391
GMR +++ ++QA+P + N+ L+ ++ + IFA +GV+LF D+ + E+ P
Sbjct: 4 GMRALLDTVMQALPQVGNLGLLFMLLFFIFAALGVELFG-------DL----ICDELHPC 52
Query: 1392 KNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAID--SREVGRQPIRET 1449
+ L Y F + G A+L LF+V+T W IM D + S++ G I
Sbjct: 53 EG---LGRYA------TFKNFGMAFLLLFRVSTGDNWNGIMKDTLRDCSQDTG---ICYN 100
Query: 1450 NIYMYLYXXXXXXXXXXXTLNLFIGVIIDNFNEQKKKA 1487
+ +Y +N+ I V++ + E K+A
Sbjct: 101 TVVSPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKEA 138
Score = 42.7 bits (96), Expect = 0.098
Identities = 26/86 (30%), Positives = 47/86 (54%), Gaps = 4/86 (4%)
Query: 845 LNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYVDYVDRFPDGDLPRW-NFT 903
+ L+ + + + +GNL + ++ FIFA +G++LFG D + P L R+ F
Sbjct: 5 MRALLDTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLICD--ELHPCEGLGRYATFK 62
Query: 904 DFMHSFMIVFRVLCGE-WIESMWDCM 928
+F +F+++FRV G+ W M D +
Sbjct: 63 NFGMAFLLLFRVSTGDNWNGIMKDTL 88
>UniRef50_A4TVG1 Cluster: Ion transport protein; n=1; Magnetospirillum
gryphiswaldense|Rep: Ion transport protein -
Magnetospirillum gryphiswaldense
Length = 270
Score = 68.5 bits (160), Expect = 2e-09
Identities = 49/156 (31%), Positives = 79/156 (50%), Gaps = 12/156 (7%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
++EN F+ +I +IL+++ L L + + H P +L +D+I VIF IE+ +K +
Sbjct: 7 IVENKIFQWFIIGVILVNAGILGL--LTMEHTPETLHVLEVLDQICLVIFCIEIAMKLIV 64
Query: 1274 LGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGM 1333
+ +F + W D I+V + AL A G +R LR LR +R S + M
Sbjct: 65 MR-GAFFKDGWNVFDVIVVGI-------ALAPATG--ELSVLRALRVLRLMRLASAIPSM 114
Query: 1334 RVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
R V+N + AIP +V V + + + AIMG F
Sbjct: 115 RRVINGMFAAIPGGGSVAAVLFVMYYVAAIMGTNFF 150
Score = 64.9 bits (151), Expect = 2e-08
Identities = 50/198 (25%), Positives = 93/198 (46%), Gaps = 19/198 (9%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALR 1591
IV +K F I+ I +N + L + + VL+ L+ I +VIF E +K+ +R
Sbjct: 7 IVENKIFQWFIIGVILVNAGILGLLTMEHTPETLHVLEVLDQICLVIFCIEIAMKLIVMR 66
Query: 1592 YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGI 1651
+F + WN+FD +VV + L+ + L V+R +V R++RL +
Sbjct: 67 GAFFKDGWNVFDVIVV-----GIALAPATGE-------LSVLRALRVLRLMRLASAIPSM 114
Query: 1652 RTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMIL 1711
R ++ + ++P ++ +LF++ ++ AI G +FF G +F +
Sbjct: 115 RRVINGMFAAIPGGGSVAAVLFVMYYVAAIMGTNFF-------GKTVPAHFGDLGTTFFT 167
Query: 1712 LFQMSTSAGWDGVLDGII 1729
LF+M T GW + ++
Sbjct: 168 LFKMMTLEGWPDIASDVL 185
Score = 54.4 bits (125), Expect = 3e-05
Identities = 40/152 (26%), Positives = 71/152 (46%), Gaps = 15/152 (9%)
Query: 137 ILVHPLFSLFIITTILVNCI---LMIMPTTP----TVESTEVIFTGIYTFESAVKVMARG 189
I+ + +F FII ILVN L+ M TP +E + I I+ E A+K+
Sbjct: 7 IVENKIFQWFIIGVILVNAGILGLLTMEHTPETLHVLEVLDQICLVIFCIEIAMKL---- 62
Query: 190 FILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIV 249
I+ + +D WN D +V+ +A + G L+ LR RVLR ++ + +P ++ ++
Sbjct: 63 -IVMRGAFFKDGWNVFDVIVVGIA---LAPATGELSVLRALRVLRLMRLASAIPSMRRVI 118
Query: 250 GAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+ ++ V + V A+MG +
Sbjct: 119 NGMFAAIPGGGSVAAVLFVMYYVAAIMGTNFF 150
>UniRef50_Q1GCI9 Cluster: Voltage-gated sodium channel; n=4;
Rhodobacteraceae|Rep: Voltage-gated sodium channel -
Silicibacter sp. (strain TM1040)
Length = 261
Score = 67.7 bits (158), Expect = 3e-09
Identities = 48/166 (28%), Positives = 87/166 (52%), Gaps = 13/166 (7%)
Query: 1208 RLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEM 1267
RLK+ ++++ F + +IL++++ L +E + + Q +L +D++ +IF E+
Sbjct: 4 RLKS--VLDSDGFSRFITAVILVNAVTLGMETSDTIMQRMGQLVLL-IDKVCLIIFVTEI 60
Query: 1268 LIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAM 1327
K L + ++F + W DF+IV V+L+ G Q F +R LR LR LR +
Sbjct: 61 AAK-LLVRRHRFFLSGWNIFDFLIVGVALVP---------GAQGFSVLRALRILRVLRVI 110
Query: 1328 SRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
S +R VV + A+P + +V L+ I + I A+M +LF +
Sbjct: 111 SVAPRLRRVVEGFITALPGMGSVFLLMAIIFYIGAVMATKLFGDSF 156
Score = 54.8 bits (126), Expect = 2e-05
Identities = 34/142 (23%), Positives = 65/142 (45%), Gaps = 6/142 (4%)
Query: 143 FSLFIITTILVNCILMIMPTTPTVESTE---VIFTGIYTFESAVKVMARGFILQPFTYLR 199
FS FI ILVN + + M T+ T+ V+ V +A +++ +
Sbjct: 14 FSRFITAVILVNAVTLGMETSDTIMQRMGQLVLLIDKVCLIIFVTEIAAKLLVRRHRFFL 73
Query: 200 DAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNL 259
WN DF+++ +A V + LR R+LR L+ +++ P L+ +V I ++ +
Sbjct: 74 SGWNIFDFLIVGVALVP---GAQGFSVLRALRILRVLRVISVAPRLRRVVEGFITALPGM 130
Query: 260 RDVIILTMFSLSVFALMGLQIY 281
V +L + A+M +++
Sbjct: 131 GSVFLLMAIIFYIGAVMATKLF 152
Score = 52.4 bits (120), Expect = 1e-04
Identities = 32/151 (21%), Positives = 73/151 (48%), Gaps = 13/151 (8%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQ-SETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFV 1596
F I I +N +T+ ++ + ++ ++ + ++IF +E K+ R+ +F+
Sbjct: 14 FSRFITAVILVNAVTLGMETSDTIMQRMGQLVLLIDKVCLIIFVTEIAAKLLVRRHRFFL 73
Query: 1597 EPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLF 1656
WN+FDF++V +++ V+R ++ RVLR++ A +R ++
Sbjct: 74 SGWNIFDFLIVGVALVP------------GAQGFSVLRALRILRVLRVISVAPRLRRVVE 121
Query: 1657 ALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+LP + ++ LL+ ++ +I A+ F
Sbjct: 122 GFITALPGMGSVFLLMAIIFYIGAVMATKLF 152
>UniRef50_A0L5S6 Cluster: Ion transport protein precursor; n=4;
Proteobacteria|Rep: Ion transport protein precursor -
Magnetococcus sp. (strain MC-1)
Length = 274
Score = 67.7 bits (158), Expect = 3e-09
Identities = 46/161 (28%), Positives = 81/161 (50%), Gaps = 12/161 (7%)
Query: 1214 LIENTYFETAVITMILLSSLALAL-EDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
LIE+ F+ + +I+L+ L L D L Q++L +D++ IF +E+ +K
Sbjct: 8 LIESKRFQNVITAIIVLNGAVLGLLTDTTLSASS--QNLLERVDQLCLTIFIVEISLKIY 65
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG 1332
A G + +F + W DF+IV + AL A G + +RT R R +R +S +
Sbjct: 66 AYGVRGFFRSGWNLFDFVIVAI-------ALMPAQG--SLSVLRTFRIFRVMRLVSVIPT 116
Query: 1333 MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
MR VV ++ A+P + +V + + + I A+M L+ +
Sbjct: 117 MRRVVQGMLLALPGVGSVAALLTVVFYIAAVMATNLYGATF 157
Score = 62.1 bits (144), Expect = 1e-07
Identities = 52/203 (25%), Positives = 96/203 (47%), Gaps = 22/203 (10%)
Query: 1531 EIVTDKKFDMIIMLFIGLNMLTM-TLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFA 1589
+++ K+F +I I LN + L S + +L+ ++ + + IF E LKI+A
Sbjct: 7 DLIESKRFQNVITAIIVLNGAVLGLLTDTTLSASSQNLLERVDQLCLTIFIVEISLKIYA 66
Query: 1590 LRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGA 1648
+F WNLFDFV+V +++ S L V+R ++ RV+RLV
Sbjct: 67 YGVRGFFRSGWNLFDFVIVAIALMPAQGS------------LSVLRTFRIFRVMRLVSVI 114
Query: 1649 KGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQS 1708
+R ++ + ++LP + ++ LL +V +I A+ + + G F +S
Sbjct: 115 PTMRRVVQGMLLALPGVGSVAALLTVVFYIAAVMATNLY-------GATFPEWFGDLSKS 167
Query: 1709 MILLFQMSTSAGWD-GVLDGIIN 1730
+ LFQ+ T W G++ ++N
Sbjct: 168 LYTLFQVMTLESWSMGIVRPVMN 190
Score = 56.4 bits (130), Expect = 7e-06
Identities = 30/116 (25%), Positives = 61/116 (52%), Gaps = 7/116 (6%)
Query: 166 VESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLA 225
+E + + I+ E ++K+ A G + R WN DFV++A+A + G+L+
Sbjct: 45 LERVDQLCLTIFIVEISLKIYAYGVR----GFFRSGWNLFDFVIVAIALMPAQ---GSLS 97
Query: 226 ALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
LRTFR+ R ++ V+++P ++ +V ++ ++ + V L + A+M +Y
Sbjct: 98 VLRTFRIFRVMRLVSVIPTMRRVVQGMLLALPGVGSVAALLTVVFYIAAVMATNLY 153
>UniRef50_A4S304 Cluster: VIC family transporter: sodium/calcium ion
channel; n=1; Ostreococcus lucimarinus CCE9901|Rep: VIC
family transporter: sodium/calcium ion channel -
Ostreococcus lucimarinus CCE9901
Length = 1012
Score = 67.3 bits (157), Expect = 4e-09
Identities = 56/218 (25%), Positives = 102/218 (46%), Gaps = 23/218 (10%)
Query: 1577 VIFSSECLLKIFALRYHY-FVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRV 1635
VI + + + LR HY F +P N DFVV + S + +Y VS L VR
Sbjct: 350 VIIKEDGVKHLVELRPHYYFHDPVNCVDFVVTVLSFM---------EYVVSGNSLDAVRT 400
Query: 1636 AKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGG 1695
++ R+LRL++ + +R +L + + ++ I +LL +V++I+A+ G F G
Sbjct: 401 FRLIRLLRLIQMVEDMRVILDGVIQGVLSIVWILVLLTVVVYIYAVIGAVLF-------G 453
Query: 1696 LDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNC----GSAT 1751
+D NF++ + + M+T + W L IN CD + C
Sbjct: 454 ENDPRNFRSLSIAFKTVISMTTMSDWLDFL--YINYHGCDQYGYDGADASYCTNPKSQKV 511
Query: 1752 IGITYLLSYLVISFLIVINMYIAVILENYSQATEDVQE 1789
+ Y++S +VI I+++++I VI A ++++
Sbjct: 512 LATAYIMSLIVILGNIMMSLFIGVITNKMEDAALELKD 549
Score = 65.7 bits (153), Expect = 1e-08
Identities = 71/342 (20%), Positives = 158/342 (46%), Gaps = 52/342 (15%)
Query: 1504 NAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDM-IIMLFIGLNMLT-MTLDHYQQS 1561
+ ++ G +PL +P+ + R Q + +VT+ F+ ++M+ I + + + + L++ QQ
Sbjct: 593 SGVRAEGVVRPLPDLPKWK-RAQLWLKRMVTNTVFEWGVVMMIIAVAITSGLGLEYNQQG 651
Query: 1562 ETFSAVLDYLNMIFIVIFSSECLLKIFA-----LRYHYFVEPW-NLFDFVVVMFSILSLV 1615
+ + + FI F++E ++K FA L ++ + W NLFD VV+ ++
Sbjct: 652 KEWYKTTE---AFFIAAFTAELIIKFFAYLDRSLSFYTGKQKWWNLFDTFVVLVGLIP-- 706
Query: 1616 LSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLV 1675
Y + ++R++R+ R+LRLV+ K ++ ++ +L + ++ + + + ++
Sbjct: 707 -----SSYQKAAVVVRLLRLL---RILRLVRVIKQLQVVVLSLIAGMNSIVYVAVFMSVI 758
Query: 1676 MFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECD 1735
F++A+ G+ F L+D ++F +++ LF +S W V D IN CD
Sbjct: 759 FFVYAVAGVQVFR-------LNDPFHFCDLSNAVVTLFTVSFLEDWRPVFD--INFYGCD 809
Query: 1736 L-----------------PDNERGSPGNCG----SATIGITYLLSYLVISFLIVINMYIA 1774
D GS C + SY+++S +++++ ++
Sbjct: 810 KNLFGDTDGGVYYASTIDVDISNGSTVVCSHPQQHKMFAFFFFSSYILLSAMVLVSAFVG 869
Query: 1775 VILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRY 1816
+I+ + A+ V++ L ++ E + + D S+ Y
Sbjct: 870 IIVTSMQSASTMVRQRLASEERLKMIEEFFQLDEHASKQTVY 911
Score = 59.7 bits (138), Expect = 8e-07
Identities = 30/111 (27%), Positives = 64/111 (57%), Gaps = 3/111 (2%)
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTF 230
++ +G+ E VK + L+P Y D N +DFVV L+++ + +L A+RTF
Sbjct: 345 IMSSGVIIKEDGVKHLVE---LRPHYYFHDPVNCVDFVVTVLSFMEYVVSGNSLDAVRTF 401
Query: 231 RVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
R++R L+ + +V ++ I+ VI+ V ++ +++L + ++A++G ++
Sbjct: 402 RLIRLLRLIQMVEDMRVILDGVIQGVLSIVWILVLLTVVVYIYAVIGAVLF 452
Score = 53.2 bits (122), Expect = 7e-05
Identities = 40/168 (23%), Positives = 79/168 (47%), Gaps = 9/168 (5%)
Query: 1204 WGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIF 1263
W +L +++ NT FE V+ MI+ ++ L L + ++ + F F
Sbjct: 610 WKRAQLWLKRMVTNTVFEWGVVMMIIAVAITSGLG---LEYNQQGKEWYKTTEAFFIAAF 666
Query: 1264 FIEMLIKWLALGFQK--YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRAL 1321
E++IK+ A + ++T W + V L+ + + + +R LR L
Sbjct: 667 TAELIIKFFAYLDRSLSFYTGKQKWWNLFDTFVVLVGLIPSSYQKAAV----VVRLLRLL 722
Query: 1322 RPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
R LR + ++ ++VVV +L+ + SI V + + + ++A+ GVQ+F
Sbjct: 723 RILRLVRVIKQLQVVVLSLIAGMNSIVYVAVFMSVIFFVYAVAGVQVF 770
Score = 47.2 bits (107), Expect = 0.005
Identities = 25/91 (27%), Positives = 53/91 (58%), Gaps = 6/91 (6%)
Query: 1279 YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVN 1338
YF + +DF++ ++S + +V + G + +RT R +R LR + ++ MRV+++
Sbjct: 368 YFHDPVNCVDFVVTVLSFMEYVVS-----G-NSLDAVRTFRLIRLLRLIQMVEDMRVILD 421
Query: 1339 ALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
++Q + SI +L++ + I+A++G LF
Sbjct: 422 GVIQGVLSIVWILVLLTVVVYIYAVIGAVLF 452
Score = 42.3 bits (95), Expect = 0.13
Identities = 27/116 (23%), Positives = 55/116 (47%), Gaps = 2/116 (1%)
Query: 167 ESTEVIFTGIYTFESAVKVMAR-GFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLA 225
++TE F +T E +K A L +T + WN D V+ + + +
Sbjct: 656 KTTEAFFIAAFTAELIIKFFAYLDRSLSFYTGKQKWWNLFDTFVVLVGLIPSSYQKAAVV 715
Query: 226 ALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+R R+LR L+ V ++ L+ +V ++I + ++ V + V+A+ G+Q++
Sbjct: 716 -VRLLRLLRILRLVRVIKQLQVVVLSLIAGMNSIVYVAVFMSVIFFVYAVAGVQVF 770
>UniRef50_A7RH57 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 958
Score = 67.3 bits (157), Expect = 4e-09
Identities = 43/155 (27%), Positives = 78/155 (50%), Gaps = 10/155 (6%)
Query: 1502 YYNAMKKMGSKKPLKA---IPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLD-H 1557
Y K+ S + LKA IP P+ Q ++++ FD + I LN++ + +
Sbjct: 419 YLQKRDKLESIRHLKASDAIPPPKTPVQLFMYKVAAHVMFDATMNGLILLNVIPIIFELE 478
Query: 1558 YQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVL- 1616
+ ++ L +N +++ +++ E + KI A R +YF WNL D +V S + +++
Sbjct: 479 ADDNASYLPTLKIINYLYVTLYTMETIWKIVAFRIYYFKAYWNLLDLFIVALSFIDIIID 538
Query: 1617 ---SDIIEKYFVSPTL--LRVVRVAKVGRVLRLVK 1646
S + F S L R+ RV ++GR+LRL+K
Sbjct: 539 QAASSSDDTSFSSTFLKTARIFRVLRMGRLLRLIK 573
Score = 46.0 bits (104), Expect = 0.011
Identities = 43/186 (23%), Positives = 85/186 (45%), Gaps = 24/186 (12%)
Query: 91 EDIDPFYHNQTTFVVISKGKDIFRFSATNALWILDPFNPIRRVAIYILVHPLFSLFIITT 150
ED+ ++ K + I A++A I P P++ + H +F +
Sbjct: 408 EDLTAYWRIPPYLQKRDKLESIRHLKASDA--IPPPKTPVQLFMYKVAAHVMFDATMNGL 465
Query: 151 ILVNCILMIMPTT--------PTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAW 202
IL+N I +I PT++ ++ +YT E+ K++A F + Y + W
Sbjct: 466 ILLNVIPIIFELEADDNASYLPTLKIINYLYVTLYTMETIWKIVA--FRIY---YFKAYW 520
Query: 203 NWLDFVVIALAYVTMGIDLGNLAA---------LRTFRVLRALKTVAIVPGLKTIVGAVI 253
N LD ++AL+++ + ID ++ L+T R+ R L+ ++ +K++V +I
Sbjct: 521 NLLDLFIVALSFIDIIIDQAASSSDDTSFSSTFLKTARIFRVLRMGRLLRLIKSVVPKII 580
Query: 254 ESVKNL 259
+ V N+
Sbjct: 581 DFVNNI 586
>UniRef50_Q9ULQ1 Cluster: Two pore calcium channel protein 1; n=23;
Euteleostomi|Rep: Two pore calcium channel protein 1 -
Homo sapiens (Human)
Length = 816
Score = 67.3 bits (157), Expect = 4e-09
Identities = 50/223 (22%), Positives = 104/223 (46%), Gaps = 10/223 (4%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
L+++ F+ + ++ ++ + + +E L + + +F I+ +E+ +K
Sbjct: 437 LVKSKAFQYFMYLVVAVNGVWILVETFMLKGGNFFSKHVPWSYLVFLTIYGVELFLKVAG 496
Query: 1274 LGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGM 1333
LG +Y ++ W DF V++ F+ L A ++ F + LR L+ LR +
Sbjct: 497 LGPVEYLSSGWNLFDF---SVTVFAFLGLLALALNMEPFYFIVVLRPLQLLRLFKLKERY 553
Query: 1334 RVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYF-KCVDMNHTTLSH---EII 1389
R V++ + + +P + ++ L LIF+ FAI+G++ F G F C + + ++
Sbjct: 554 RNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHT 613
Query: 1390 PDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIM 1432
E Y + N NFD++ +++ LF++ W IM
Sbjct: 614 VGNRTVVEEGYYYLN---NFDNILNSFVTLFELTVVNNWYIIM 653
Score = 62.5 bits (145), Expect = 1e-07
Identities = 44/159 (27%), Positives = 78/159 (49%), Gaps = 9/159 (5%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHY--QQSETFSAVLDYLNMIFIVIFSSECLLKIFA 1589
+V K F + L + +N + + ++ + + FS + + ++F+ I+ E LK+
Sbjct: 437 LVKSKAFQYFMYLVVAVNGVWILVETFMLKGGNFFSKHVPWSYLVFLTIYGVELFLKVAG 496
Query: 1590 LR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGA 1648
L Y WNLFDF V +F+ L L+ + + F +LR +++ LRL K
Sbjct: 497 LGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIVVLRPLQL------LRLFKLK 550
Query: 1649 KGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
+ R +L + LP + ++ L L + + FAI GM FF
Sbjct: 551 ERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFF 589
Score = 47.2 bits (107), Expect = 0.005
Identities = 46/171 (26%), Positives = 76/171 (44%), Gaps = 26/171 (15%)
Query: 1613 SLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLV--KGAKGIRTLLFALAMSLPALFNICL 1670
S+++ +E V + VRV + R + LV + G+R L + SLP +I L
Sbjct: 178 SVLVVQFVEAIVVLVRQMSHVRVTRALRCIFLVDCRYCGGVRRNLRQIFQSLPPFMDILL 237
Query: 1671 LLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIIN 1730
LL M IFAI G F D Y F T S++ LF + T+A + V+
Sbjct: 238 LLLFFMIIFAILGFYLF-----SPNPSDPY-FSTLENSIVSLFVLLTTANFPDVM----- 286
Query: 1731 EEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILENYS 1781
+P R +P +C + + YL I ++N+ +AV+ + ++
Sbjct: 287 -----MPSYSR-NPWSC-------VFFIVYLSIELYFIMNLLLAVVFDTFN 324
Score = 42.7 bits (96), Expect = 0.098
Identities = 28/115 (24%), Positives = 57/115 (49%), Gaps = 9/115 (7%)
Query: 1258 IFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRT 1317
+ V+F + M ++WL G + + + +++V + + L ++ +R
Sbjct: 148 LMVVVFELCMKLRWL--GLHTFIRHKRTMVKTSVLVVQFVEAIVVL-----VRQMSHVRV 200
Query: 1318 LRALRPLRAMSRMQ--GMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
RALR + + G+R + + Q++P ++LL+ L F +IFAI+G LF+
Sbjct: 201 TRALRCIFLVDCRYCGGVRRNLRQIFQSLPPFMDILLLLLFFMIIFAILGFYLFS 255
Score = 42.3 bits (95), Expect = 0.13
Identities = 25/122 (20%), Positives = 54/122 (44%), Gaps = 7/122 (5%)
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAY---VTMGIDLGNLAAL 227
++F IY E +KV G P YL WN DF V A+ + + +++ +
Sbjct: 480 LVFLTIYGVELFLKVAGLG----PVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFI 535
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQ 287
R L+ L+ + + ++ + E + + + + + FA++G++ + G++
Sbjct: 536 VVLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFP 595
Query: 288 KC 289
C
Sbjct: 596 NC 597
>UniRef50_A1WZ39 Cluster: Ion transport protein; n=5;
Proteobacteria|Rep: Ion transport protein -
Halorhodospira halophila (strain DSM 244 / SL1)
(Ectothiorhodospirahalophila (strain DSM 244 / SL1))
Length = 300
Score = 66.5 bits (155), Expect = 7e-09
Identities = 43/160 (26%), Positives = 85/160 (53%), Gaps = 11/160 (6%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLA 1273
L+E F+ VI +I ++ + L LE + + ++ + F +E+ ++ +A
Sbjct: 29 LVEARLFQNTVIAVICINGVTLGLETSD-DLVAWSRGAIPLINELILAFFVVEIALRVVA 87
Query: 1274 LGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGM 1333
G ++F W DF IV +SL+ AG A+ +R LR LR LR +S++ +
Sbjct: 88 WG-PRFFRGPWNLFDFGIVAISLVP------DAG---AYSVLRALRILRLLRLLSQVSRL 137
Query: 1334 RVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKY 1373
R++V +L++A+P I + ++ + + +FA+MG +L+ +
Sbjct: 138 RIIVESLLRALPGIGWIGVLLGLVYYVFAVMGTELYGNTF 177
Score = 61.7 bits (143), Expect = 2e-07
Identities = 50/202 (24%), Positives = 90/202 (44%), Gaps = 20/202 (9%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFS-AVLDYLNMIFIVIFSSECLLKIFAL 1590
+V + F ++ I +N +T+ L+ +S + +N + + F E L++ A
Sbjct: 29 LVEARLFQNTVIAVICINGVTLGLETSDDLVAWSRGAIPLINELILAFFVVEIALRVVAW 88
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
+F PWNLFDF +V S++ V+R ++ R+LRL+
Sbjct: 89 GPRFFRGPWNLFDFGIVAISLVP------------DAGAYSVLRALRILRLLRLLSQVSR 136
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMI 1710
+R ++ +L +LP + I +LL LV ++FA+ G + + F + SM
Sbjct: 137 LRIIVESLLRALPGIGWIGVLLGLVYYVFAVMGTELYGNTFPDW-------FGSIGASMY 189
Query: 1711 LLFQMSTSAGWDGVLDGIINEE 1732
LFQ+ T W + + EE
Sbjct: 190 TLFQVMTLESWSEAIARPVMEE 211
Score = 51.2 bits (117), Expect = 3e-04
Identities = 32/110 (29%), Positives = 59/110 (53%), Gaps = 8/110 (7%)
Query: 172 IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFR 231
+ + E A++V+A G P + R WN DF ++A++ V D G + LR R
Sbjct: 72 LILAFFVVEIALRVVAWG----P-RFFRGPWNLFDFGIVAISLVP---DAGAYSVLRALR 123
Query: 232 VLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
+LR L+ ++ V L+ IV +++ ++ + + +L VFA+MG ++Y
Sbjct: 124 ILRLLRLLSQVSRLRIIVESLLRALPGIGWIGVLLGLVYYVFAVMGTELY 173
Score = 39.1 bits (87), Expect = 1.2
Identities = 16/62 (25%), Positives = 36/62 (58%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L++ LR+ +L L +++ + R + +G + +L ++ ++FAVMG +L+G +
Sbjct: 119 LRALRILRLLRLLSQVSRLRIIVESLLRALPGIGWIGVLLGLVYYVFAVMGTELYGNTFP 178
Query: 887 DY 888
D+
Sbjct: 179 DW 180
>UniRef50_A7SGC6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 498
Score = 66.5 bits (155), Expect = 7e-09
Identities = 60/250 (24%), Positives = 108/250 (43%), Gaps = 37/250 (14%)
Query: 1235 LALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMV 1294
L + + P L+ L D IF IE+++KW+ GF ++ N W DF + ++
Sbjct: 115 LEVSQITDPSLDALKVTLNVFDFCALTIFVIEIIVKWID-GFWSFWNNGWNIFDFFVTIM 173
Query: 1295 SL----INFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNV 1350
S+ I F + A +R R LR L+ +SR +R++V +++A S+ +
Sbjct: 174 SVVPEVIKFSSGQNTAEVAVIADNLRVFRILRSLKMVSRFAQLRIIVLTILKAFKSMAFI 233
Query: 1351 LLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFD 1410
+++ + F IFA+ G +FA N T L ++ +F
Sbjct: 234 MILLMTFMYIFAVAGTVIFA----SAAKSNRTDLKYK-------------------TSFS 270
Query: 1411 HVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLN 1470
+G A + LFQ+ T W I+ + + + V + IY+ L+ N
Sbjct: 271 TLGNALITLFQLFTLDHWYMILTEHV--KVVN---VVTAQIYIILWICIGAFIFR----N 321
Query: 1471 LFIGVIIDNF 1480
+F G+++ NF
Sbjct: 322 IFAGIMVMNF 331
Score = 60.5 bits (140), Expect = 5e-07
Identities = 50/237 (21%), Positives = 106/237 (44%), Gaps = 14/237 (5%)
Query: 1492 EMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNML 1551
+M+ +D++K+++ +++ K +IP W V + + ++ + L L +
Sbjct: 67 QMYSKKDEQKFHD--RRLNRVKNKNSIPLGPWA------HTVVEGQHNIFMCLLFYLEVS 118
Query: 1552 TMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSI 1611
+T + L+ + + IF E ++K + ++ WN+FDF V + S+
Sbjct: 119 QIT---DPSLDALKVTLNVFDFCALTIFVIEIIVKWIDGFWSFWNNGWNIFDFFVTIMSV 175
Query: 1612 LSLVLSDIIEKYFVSPTLLRV-VRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICL 1670
+ V+ + ++ +RV ++ R L++V +R ++ + + ++ I +
Sbjct: 176 VPEVIKFSSGQNTAEVAVIADNLRVFRILRSLKMVSRFAQLRIIVLTILKAFKSMAFIMI 235
Query: 1671 LLFLVMFIFAIFGMSFFMHVKDKGGLDDVY--NFKTFVQSMILLFQMSTSAGWDGVL 1725
LL M+IFA+ G F D Y +F T ++I LFQ+ T W +L
Sbjct: 236 LLMTFMYIFAVAGTVIFASAAKSNRTDLKYKTSFSTLGNALITLFQLFTLDHWYMIL 292
Score = 44.4 bits (100), Expect = 0.032
Identities = 28/97 (28%), Positives = 53/97 (54%), Gaps = 10/97 (10%)
Query: 195 FTYLRDAWNWLDFVVIALAYV------TMGIDLGNLAA----LRTFRVLRALKTVAIVPG 244
+++ + WN DF V ++ V + G + +A LR FR+LR+LK V+
Sbjct: 156 WSFWNNGWNIFDFFVTIMSVVPEVIKFSSGQNTAEVAVIADNLRVFRILRSLKMVSRFAQ 215
Query: 245 LKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
L+ IV ++++ K++ ++IL M + +FA+ G I+
Sbjct: 216 LRIIVLTILKAFKSMAFIMILLMTFMYIFAVAGTVIF 252
>UniRef50_Q8NEC5 Cluster: Cation channel sperm-associated protein 1;
n=23; Eutheria|Rep: Cation channel sperm-associated
protein 1 - Homo sapiens (Human)
Length = 780
Score = 66.5 bits (155), Expect = 7e-09
Identities = 58/253 (22%), Positives = 108/253 (42%), Gaps = 31/253 (12%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSA-VLDYLNMIFIVIFSSECLLKIFALRYHYFV 1596
F+ I + LN + + + + E L+ IF I+ E LLKI AL YF
Sbjct: 449 FETFIFFVVCLNTVMLVAQTFAEVEIRGEWYFMALDSIFFCIYVVEALLKIIALGLSYFF 508
Query: 1597 EPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK------G 1650
+ WN DF ++ ++L +L +L R+++V K R LR ++ +
Sbjct: 509 DFWNNLDFFIMAMAVLDFLLMQTHSFAIYHQSLFRILKVFKSLRALRAIRVLRRLSFLTS 568
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMI 1710
++ + L SLP++ I +L+F +F+F+ + F D F+ ++
Sbjct: 569 VQEVTGTLGQSLPSIAAILILMFTCLFLFSAVLRALFRK-------SDPKRFQNIFTTIF 621
Query: 1711 LLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVIN 1770
LF + T W + + +G A I L+ Y++I + I +N
Sbjct: 622 TLFTLLTLDDWSLIY----------MDSRAQG-------AWYIIPILIIYIIIQYFIFLN 664
Query: 1771 MYIAVILENYSQA 1783
+ I V+++++ A
Sbjct: 665 LVITVLVDSFQTA 677
Score = 64.1 bits (149), Expect = 4e-08
Identities = 47/167 (28%), Positives = 88/167 (52%), Gaps = 15/167 (8%)
Query: 1214 LIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYM--DRIFTVIFFIEMLIKW 1271
L ++ FET + ++ L+++ L + ++ Y+M D IF I+ +E L+K
Sbjct: 443 LTQSLAFETFIFFVVCLNTVMLVAQTFAEVE---IRGEWYFMALDSIFFCIYVVEALLKI 499
Query: 1272 LALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGI---------QAFKTMRTLRALR 1322
+ALG YF + W LDF I+ +++++F+ + I + FK++R LRA+R
Sbjct: 500 IALGLS-YFFDFWNNLDFFIMAMAVLDFLLMQTHSFAIYHQSLFRILKVFKSLRALRAIR 558
Query: 1323 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
LR +S + ++ V L Q++PSI +L++ +F+ + LF
Sbjct: 559 VLRRLSFLTSVQEVTGTLGQSLPSIAAILILMFTCLFLFSAVLRALF 605
Score = 44.0 bits (99), Expect = 0.042
Identities = 37/155 (23%), Positives = 73/155 (47%), Gaps = 28/155 (18%)
Query: 143 FSLFIITTILVNCILMIMPTTPTVE--------STEVIFTGIYTFESAVKVMARGFILQP 194
F FI + +N ++++ T VE + + IF IY E+ +K++A G
Sbjct: 449 FETFIFFVVCLNTVMLVAQTFAEVEIRGEWYFMALDSIFFCIYVVEALLKIIALGL---- 504
Query: 195 FTYLRDAWNWLDFVVIALA---YVTMGID------------LGNLAALRTFRVLRALKTV 239
+Y D WN LDF ++A+A ++ M L +LR R +R L+ +
Sbjct: 505 -SYFFDFWNNLDFFIMAMAVLDFLLMQTHSFAIYHQSLFRILKVFKSLRALRAIRVLRRL 563
Query: 240 AIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFA 274
+ + ++ + G + +S+ ++ ++IL L +F+
Sbjct: 564 SFLTSVQEVTGTLGQSLPSIAAILILMFTCLFLFS 598
>UniRef50_UPI0000F1EB94 Cluster: PREDICTED: hypothetical protein; n=1;
Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
rerio
Length = 496
Score = 66.1 bits (154), Expect = 9e-09
Identities = 45/149 (30%), Positives = 79/149 (53%), Gaps = 11/149 (7%)
Query: 1572 NMIFIVIFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLL 1630
N + + +F+ E LLK+++L YFV +N FD VV IL VL +E + P +
Sbjct: 336 NKVLLSLFTVEMLLKMYSLGLQVYFVAFFNRFDCFVVCGGILETVL---VEMEIMPPLGI 392
Query: 1631 RVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHV 1690
V+R ++ R+ ++ + + L+ +L S+ ++ ++ LLLFL + IFA+ GM F
Sbjct: 393 SVLRCVRLLRIFKVTRHWTALSNLVASLLNSMKSIASLLLLLFLFLIIFALLGMQLF--- 449
Query: 1691 KDKGGLDDVY----NFKTFVQSMILLFQM 1715
K D+ F +F Q+++ FQ+
Sbjct: 450 GGKFNFDETQTKRSTFDSFPQALLTCFQI 478
Score = 62.9 bits (146), Expect = 9e-08
Identities = 39/138 (28%), Positives = 68/138 (49%), Gaps = 7/138 (5%)
Query: 1236 ALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVS 1295
AL+ + HR I +L + F +EML+K +LG Q YF + D +V
Sbjct: 323 ALQPTRMAHRHIANKVLLSL-------FTVEMLLKMYSLGLQVYFVAFFNRFDCFVVCGG 375
Query: 1296 LINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCL 1355
++ V +R +R LR + + +V +L+ ++ SI ++LL+
Sbjct: 376 ILETVLVEMEIMPPLGISVLRCVRLLRIFKVTRHWTALSNLVASLLNSMKSIASLLLLLF 435
Query: 1356 IFWLIFAIMGVQLFAGKY 1373
+F +IFA++G+QLF GK+
Sbjct: 436 LFLIIFALLGMQLFGGKF 453
Score = 50.8 bits (116), Expect = 4e-04
Identities = 25/89 (28%), Positives = 48/89 (53%), Gaps = 5/89 (5%)
Query: 827 LKSGNYLRVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGKNYV 886
L+ LR+FK+ + W L+ L++ + +M ++ +L +L + + IFA++GMQLFG +
Sbjct: 395 LRCVRLLRIFKVTRHWTALSNLVASLLNSMKSIASLLLLLFLFLIIFALLGMQLFGGKF- 453
Query: 887 DYVDRFPDGDLPRWNFTDFMHSFMIVFRV 915
F + R F F + + F++
Sbjct: 454 ----NFDETQTKRSTFDSFPQALLTCFQI 478
Score = 42.3 bits (95), Expect = 0.13
Identities = 18/60 (30%), Positives = 36/60 (60%)
Query: 224 LAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMG 283
++ LR R+LR K L +V +++ S+K++ +++L L +FAL+G+Q++ G
Sbjct: 392 ISVLRCVRLLRIFKVTRHWTALSNLVASLLNSMKSIASLLLLLFLFLIIFALLGMQLFGG 451
>UniRef50_UPI0000E47103 Cluster: PREDICTED: similar to
sperm-associated cation channel 2; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
sperm-associated cation channel 2 - Strongylocentrotus
purpuratus
Length = 493
Score = 65.7 bits (153), Expect = 1e-08
Identities = 67/264 (25%), Positives = 123/264 (46%), Gaps = 42/264 (15%)
Query: 1221 ETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYF 1280
ET +++ LLS +A D P + L D +F +E+L+KW+ F ++
Sbjct: 118 ETNSLSLGLLSEVA----DRTDPSLAGTRRFLEIFDYCALFLFMVEILLKWVD-NFPLFW 172
Query: 1281 TNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTM----RTLRALRPLRAMSRMQGMRVV 1336
N W DF++ + S I + A AG ++ K + R R R L+ +SR + R++
Sbjct: 173 KNGWNIFDFVVTVASFIPEIIA-SAAGDLEDLKVIVGNIRVFRIFRALKMVSRFRQARMI 231
Query: 1337 VNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACT 1396
A+ +A ++ +L++ L+F IFAI G+ +F Y + + L+H+
Sbjct: 232 ALAITKAFNAMSFILVLFLLFLYIFAITGI-IFFDSYSRSM---RDDLTHQ--------- 278
Query: 1397 LENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLY 1456
+F+++G A + LFQ+ T W +I+ D + +G + T Y+ L+
Sbjct: 279 ----------HSFNNLGNAMITLFQLFTLDQWYKILKDM--WKVMG--SVAPT-FYIMLW 323
Query: 1457 XXXXXXXXXXXTLNLFIGVIIDNF 1480
NLF+G++++NF
Sbjct: 324 ICIGSFIFK----NLFVGIMVNNF 343
Score = 63.3 bits (147), Expect = 6e-08
Identities = 42/160 (26%), Positives = 76/160 (47%), Gaps = 2/160 (1%)
Query: 1568 LDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSP 1627
L+ + + +F E LLK ++ WN+FDFVV + S + +++
Sbjct: 145 LEIFDYCALFLFMVEILLKWVDNFPLFWKNGWNIFDFVVTVASFIPEIIASAAGDLEDLK 204
Query: 1628 TLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFF 1687
++ +RV ++ R L++V + R + A+ + A+ I +L L ++IFAI G+ FF
Sbjct: 205 VIVGNIRVFRIFRALKMVSRFRQARMIALAITKAFNAMSFILVLFLLFLYIFAITGIIFF 264
Query: 1688 MHVKD--KGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVL 1725
+ L ++F +MI LFQ+ T W +L
Sbjct: 265 DSYSRSMRDDLTHQHSFNNLGNAMITLFQLFTLDQWYKIL 304
Score = 39.5 bits (88), Expect = 0.91
Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 9/91 (9%)
Query: 197 YLRDAWNWLDFVVIALAYVTMGI-----DLGNLAAL----RTFRVLRALKTVAIVPGLKT 247
+ ++ WN DFVV +++ I DL +L + R FR+ RALK V+ +
Sbjct: 171 FWKNGWNIFDFVVTVASFIPEIIASAAGDLEDLKVIVGNIRVFRIFRALKMVSRFRQARM 230
Query: 248 IVGAVIESVKNLRDVIILTMFSLSVFALMGL 278
I A+ ++ + +++L + L +FA+ G+
Sbjct: 231 IALAITKAFNAMSFILVLFLLFLYIFAITGI 261
>UniRef50_A5DVK2 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 550
Score = 65.7 bits (153), Expect = 1e-08
Identities = 36/136 (26%), Positives = 69/136 (50%), Gaps = 5/136 (3%)
Query: 1701 NFKTFVQSMILLFQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYLLS 1759
N ++ +++I+LF+ S GW+ ++ D ++ C N S +CGS ++
Sbjct: 19 NLRSVPKTLIVLFRCSFGEGWNYIMEDYTLSPPFCTNEKNLDHS--DCGSKQYAYILFIA 76
Query: 1760 YLVISFLIVINMYIAVILENYSQATEDVQEG--LTDDDYDMYYEIWQRFDPDGSQYIRYD 1817
+ +IS I +NM+I++IL+ + + + G + ++ + WQ+FDP G+ YI+
Sbjct: 77 WNIISMYIFLNMFISLILDGFDYVNQKTRYGDLIKREEIRKFKRTWQKFDPQGTGYIKPI 136
Query: 1818 QLSDFLDVLEPPLQIH 1833
+L L L L H
Sbjct: 137 ELPQLLHALHGALSFH 152
>UniRef50_UPI000155F67E Cluster: PREDICTED: hypothetical protein; n=3;
Laurasiatheria|Rep: PREDICTED: hypothetical protein -
Equus caballus
Length = 849
Score = 65.3 bits (152), Expect = 2e-08
Identities = 67/285 (23%), Positives = 128/285 (44%), Gaps = 29/285 (10%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
+++ + F +IL++++ +AL++ P + Y + +F ++ IE+L+K
Sbjct: 460 RMVRHRVFVWVYDVIILVNAIFIALDE----RNPFIS----YAEWLFLSLYIIEILLKLY 511
Query: 1273 ALGFQKYFTNA--WCWLDFIIVMVSLINFVA--ALCGA---GGIQAFKTMRTLRALRPLR 1325
+ YF W W D +I++ +L+ VA + A Q + LR LR LR
Sbjct: 512 TYEPRSYFGRRQFWNWFDVLILIAALVATVANTTIQSARKYSSQQILDIVLILRILRLLR 571
Query: 1326 AMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLS 1385
+ ++ RV+V L+ P++ + L+ + +FAI+G++ F K + D N T
Sbjct: 572 VIVSIERFRVIVTTLINIGPAMLTFGGLVLVVYYVFAIIGMEAFHSK-VQFFDPNFTAPD 630
Query: 1386 HEIIPD---KNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMN-DAIDSRE- 1440
+ + K++ N +N NF+ + A++ L ++ W I++ +A DSR
Sbjct: 631 ALVCGNPALKDSAFARNRYCKN---NFNDLASAFILLMELTVVNQWHDILSGEASDSRRG 687
Query: 1441 -----VGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFIGVIIDNF 1480
VG T+ LY +N+FI I++ F
Sbjct: 688 CLLSGVGGGFALVTHQAAKLYFVGFHIVVVILIVNIFIAFILEAF 732
Score = 60.5 bits (140), Expect = 5e-07
Identities = 62/302 (20%), Positives = 130/302 (43%), Gaps = 42/302 (13%)
Query: 1515 LKAIPRPRWRPQA-------IVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAV 1567
+K P W P+ +V +V + F + + I +N + + LD +
Sbjct: 437 IKRHPLEAWMPRVYQSSASLLVQRMVRHRVFVWVYDVIILVNAIFIALDER------NPF 490
Query: 1568 LDYLNMIFIVIFSSECLLKIFALRYH-YFVEP--WNLFDFVVVMFSILSLVLSDIIE--K 1622
+ Y +F+ ++ E LLK++ YF WN FD ++++ ++++ V + I+ +
Sbjct: 491 ISYAEWLFLSLYIIEILLKLYTYEPRSYFGRRQFWNWFDVLILIAALVATVANTTIQSAR 550
Query: 1623 YFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIF 1682
+ S +L +V + ++ R+LR++ + R ++ L PA+ L+ +V ++FAI
Sbjct: 551 KYSSQQILDIVLILRILRLLRVIVSIERFRVIVTTLINIGPAMLTFGGLVLVVYYVFAII 610
Query: 1683 GMSFFMH---------------------VKDKGGLDDVY---NFKTFVQSMILLFQMSTS 1718
GM F +KD + Y NF + ILL +++
Sbjct: 611 GMEAFHSKVQFFDPNFTAPDALVCGNPALKDSAFARNRYCKNNFNDLASAFILLMELTVV 670
Query: 1719 AGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVINMYIAVILE 1778
W +L G ++ + G + Y + + ++ ++++N++IA ILE
Sbjct: 671 NQWHDILSGEASDSRRGCLLSGVGGGFALVTHQAAKLYFVGFHIVVVILIVNIFIAFILE 730
Query: 1779 NY 1780
+
Sbjct: 731 AF 732
Score = 40.7 bits (91), Expect = 0.40
Identities = 35/134 (26%), Positives = 63/134 (47%), Gaps = 11/134 (8%)
Query: 140 HPLFSLFIITTILVNCILMIMPT-TPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYL 198
H +F ILVN I + + P + E +F +Y E +K+ + +P +Y
Sbjct: 464 HRVFVWVYDVIILVNAIFIALDERNPFISYAEWLFLSLYIIEILLKL----YTYEPRSYF 519
Query: 199 --RDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESV 256
R WNW D V+I +A + + + + R + + L V I+ L+ + VI S+
Sbjct: 520 GRRQFWNWFD-VLILIAALVATVANTTIQSARKYSSQQILDIVLILRILRLL--RVIVSI 576
Query: 257 KNLRDVIILTMFSL 270
+ R VI+ T+ ++
Sbjct: 577 ERFR-VIVTTLINI 589
>UniRef50_A7RM05 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 722
Score = 64.9 bits (151), Expect = 2e-08
Identities = 52/180 (28%), Positives = 88/180 (48%), Gaps = 16/180 (8%)
Query: 1259 FTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTL 1318
F +++ E L+K + LG ++YF + W DFI+ ++ +I + A + I AF + L
Sbjct: 426 FFLVYGTEALLKIIGLGAKQYFRSGWNCFDFIVTVLGIIGAIGASAKSFSI-AF--IVCL 482
Query: 1319 RALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG-KYFKCV 1377
R LR L Q R V++ + +P +F V LV L + + I+G++ F+G K C
Sbjct: 483 RPLRLLLLFKLKQRYRDVLDTIWVLMPRMFRVALVILCLYYSYGIIGLECFSGLKLKNC- 541
Query: 1378 DMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMNDAID 1437
N T++ D N Y + N NFD + A++ LF++ W IM ++
Sbjct: 542 -CNGTSV------DVN-YRESGYYYLN---NFDDLLHAFVTLFELTVVNNWFIIMEGVVN 590
Score = 57.2 bits (132), Expect = 4e-06
Identities = 41/173 (23%), Positives = 79/173 (45%), Gaps = 21/173 (12%)
Query: 1573 MIFIVIFSSECLLKIFAL-RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLR 1631
+ F +++ +E LLKI L YF WN FDF+V + I+ + + LR
Sbjct: 424 LTFFLVYGTEALLKIIGLGAKQYFRSGWNCFDFIVTVLGIIGAIGASAKSFSIAFIVCLR 483
Query: 1632 VVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVK 1691
+ R+L L K + R +L + + +P +F + L++ + + + I G+ F +K
Sbjct: 484 PL------RLLLLFKLKQRYRDVLDTIWVLMPRMFRVALVILCLYYSYGIIGLECFSGLK 537
Query: 1692 DKG-----GLDDVY---------NFKTFVQSMILLFQMSTSAGWDGVLDGIIN 1730
K +D Y NF + + + LF+++ W +++G++N
Sbjct: 538 LKNCCNGTSVDVNYRESGYYYLNNFDDLLHAFVTLFELTVVNNWFIIMEGVVN 590
Score = 48.8 bits (111), Expect = 0.001
Identities = 39/156 (25%), Positives = 75/156 (48%), Gaps = 26/156 (16%)
Query: 1633 VRVAKVGRVLRLVKG--AKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHV 1690
VRV + R L L+ +G+R L + +SLP + ++ +LL +FIFA+ G F
Sbjct: 142 VRVTRALRPLFLIDSFYLRGVRRTLRQVMLSLPPILDMLVLLLFFIFIFAMLGFYLF--- 198
Query: 1691 KDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSA 1750
DD Y F TF +S I LF + T+A + V+ +P + +
Sbjct: 199 --SSNQDDEY-FTTFERSFISLFVLLTTANYPDVM----------MP--------SYAKS 237
Query: 1751 TIGITYLLSYLVISFLIVINMYIAVILENYSQATED 1786
+ + ++Y+ ++ ++N+ +AV+ + ++ +D
Sbjct: 238 RWSVIFFIAYISVALYFLMNLLLAVVYDTFTSIEKD 273
Score = 46.4 bits (105), Expect = 0.008
Identities = 31/109 (28%), Positives = 60/109 (55%), Gaps = 11/109 (10%)
Query: 1264 FIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRP 1323
F++M KW G + +FT+ F+++ V I + + I++ +R RALRP
Sbjct: 100 FVKM--KWQ--GLKSFFTHKRSLAKFLVLCVMYIEAIVVV-----IRSKNHVRVTRALRP 150
Query: 1324 LRAMSR--MQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
L + ++G+R + ++ ++P I ++L++ L F IFA++G LF+
Sbjct: 151 LFLIDSFYLRGVRRTLRQVMLSLPPILDMLVLLLFFIFIFAMLGFYLFS 199
>UniRef50_Q1RKX8 Cluster: IP14892p; n=1; Drosophila
melanogaster|Rep: IP14892p - Drosophila melanogaster
(Fruit fly)
Length = 226
Score = 64.1 bits (149), Expect = 4e-08
Identities = 32/101 (31%), Positives = 56/101 (55%), Gaps = 10/101 (9%)
Query: 120 ALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIMPT----------TPTVEST 169
+L+IL NPIR+ +I+ P F ++ TI+ NC+++ + +E T
Sbjct: 123 SLFILTEDNPIRKYTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPGGDKTVLAQKLEKT 182
Query: 170 EVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVI 210
E F I+ E+++K++A G +L +YLR+ WN +DF V+
Sbjct: 183 EAYFLCIFCVEASLKILALGLVLHKHSYLRNIWNIMDFFVV 223
Score = 46.0 bits (104), Expect = 0.011
Identities = 33/93 (35%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
Query: 1207 LRLKTFKLIENTYFETAVITMILLSSLALALEDVHLP--HRPILQDILYYMDRIFTVIFF 1264
+R T +IE FE AV+ I+ + + LALE+ HLP + +L L + F IF
Sbjct: 133 IRKYTRFIIEWPPFEYAVLLTIIANCVVLALEE-HLPGGDKTVLAQKLEKTEAYFLCIFC 191
Query: 1265 IEMLIKWLALGF----QKYFTNAWCWLDFIIVM 1293
+E +K LALG Y N W +DF +V+
Sbjct: 192 VEASLKILALGLVLHKHSYLRNIWNIMDFFVVV 224
>UniRef50_A0EAP2 Cluster: Chromosome undetermined scaffold_86, whole
genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_86, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 1176
Score = 63.7 bits (148), Expect = 5e-08
Identities = 44/144 (30%), Positives = 77/144 (53%), Gaps = 19/144 (13%)
Query: 1567 VLDYLNMIFIVIFSSECLLKIFALRY-HYFVEPWNLFDFVVVMFSIL-SLVLSDIIEKYF 1624
+ + L+ IF+V++S ECL+KI AL YF E WN+FD +V+ I+ +L ++
Sbjct: 456 IFNSLDTIFLVLYSMECLVKIVALGIGEYFNEGWNVFDISLVILQIIFDYILFKVVTGNI 515
Query: 1625 V-SPTLLRVVRVAKVGRVLRLVKG----------AKGI------RTLLFALAMSLPALFN 1667
V S R++R+AK+ +V RL + KG+ R LL+ + +P +F
Sbjct: 516 VQSIKANRILRLAKIQKVFRLFRAFRSVKIISFLLKGVEFLDVVRRLLYKILFCIPIIFR 575
Query: 1668 ICLLLFLVMFIFAIFGMSFFMHVK 1691
+ + + +V FI+A G+ + V+
Sbjct: 576 LMMPVQMVFFIYATIGIYVYGDVE 599
Score = 51.6 bits (118), Expect = 2e-04
Identities = 33/126 (26%), Positives = 65/126 (51%), Gaps = 4/126 (3%)
Query: 1213 KLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
+ IE ++F T+++ ++ +++ L + + +L DI +D IF V++ +E L+K +
Sbjct: 420 RFIEGSFFGTSML-VVTITNCILIIAAFFIEDLSVL-DIFNSLDTIFLVLYSMECLVKIV 477
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLI-NFVAALCGAGGI-QAFKTMRTLRALRPLRAMSRM 1330
ALG +YF W D +V++ +I +++ G I Q+ K R LR + +
Sbjct: 478 ALGIGEYFNEGWNVFDISLVILQIIFDYILFKVVTGNIVQSIKANRILRLAKIQKVFRLF 537
Query: 1331 QGMRVV 1336
+ R V
Sbjct: 538 RAFRSV 543
>UniRef50_UPI0000D565C8 Cluster: PREDICTED: similar to two pore
channel 1; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to two pore channel 1 - Tribolium castaneum
Length = 781
Score = 63.3 bits (147), Expect = 6e-08
Identities = 53/218 (24%), Positives = 99/218 (45%), Gaps = 11/218 (5%)
Query: 1219 YFETAVITMILLSSLAL---ALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALG 1275
YFE V +I+ + LA+ LE + +F +F IE L++ + LG
Sbjct: 428 YFEHIVYVLIIGNGLAMFIRVLESSVSLEEGAKNFCASWDTYLFLTLFLIEALLRIVGLG 487
Query: 1276 FQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRV 1335
+ +Y ++ W + D + +V+LI + L + LR LR LR + R
Sbjct: 488 WGEYISSGWNFFDLTVTLVALIGSLILLVR----PKLTVVVILRPLRLLRLFKLKKRYRD 543
Query: 1336 VVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNAC 1395
+ LV P +++ +V ++ + FAI+G++LF+ +Y N TT+ N+
Sbjct: 544 IFGTLVLLSPLMWSTAIVMMVMYYFFAIIGMELFS-QYDLRNCCNGTTVEDFYKYSTNSS 602
Query: 1396 TLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMN 1433
+ Y + N NF ++ + + LF++ W +M+
Sbjct: 603 SGIGYYYLN---NFSNLLISGVTLFELTVVNNWFIVMD 637
Score = 58.0 bits (134), Expect = 2e-06
Identities = 68/287 (23%), Positives = 129/287 (44%), Gaps = 32/287 (11%)
Query: 1532 IVTDKKFDMIIMLFI---GLNMLTMTLDHY----QQSETFSAVLDYLNMIFIVIFSSECL 1584
+VT + F+ I+ + I GL M L+ + ++ F A D +F+ +F E L
Sbjct: 423 VVTWEYFEHIVYVLIIGNGLAMFIRVLESSVSLEEGAKNFCASWD--TYLFLTLFLIEAL 480
Query: 1585 LKIFALRY-HYFVEPWNLFDFVVVMFSIL-SLVLSDIIEKYFVSPTLLRVVRVAKVGRVL 1642
L+I L + Y WN FD V + +++ SL+L V P L VV + + R+L
Sbjct: 481 LRIVGLGWGEYISSGWNFFDLTVTLVALIGSLIL-------LVRPKLTVVV-ILRPLRLL 532
Query: 1643 RLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKG-----GLD 1697
RL K K R + L + P +++ +++ ++ + FAI GM F + ++
Sbjct: 533 RLFKLKKRYRDIFGTLVLLSPLMWSTAIVMMVMYYFFAIIGMELFSQYDLRNCCNGTTVE 592
Query: 1698 DVYNFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDN---ERGSPGNCGSATIGI 1754
D Y + T S I + ++ + +L + E + +N + N + I
Sbjct: 593 DFYKYSTNSSSGIGYYYLN---NFSNLLISGVTLFELTVVNNWFIVMDAYANVAHSYSRI 649
Query: 1755 TYLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYE 1801
++L YL ++V+ + +A +LE + + ++ D+ M +E
Sbjct: 650 FFMLFYLFT--MVVLTIVVASVLEAFRFRIQYKKQTSKRDEEQMLHE 694
>UniRef50_Q4RST2 Cluster: Chromosome 12 SCAF14999, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 12
SCAF14999, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 832
Score = 63.3 bits (147), Expect = 6e-08
Identities = 44/159 (27%), Positives = 80/159 (50%), Gaps = 10/159 (6%)
Query: 1258 IFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRT 1317
+F I+ +E+L+K LG YF++ W DF + + + + +A A ++ F +
Sbjct: 498 VFLTIYGVEVLLKISGLGPMAYFSSGWNLFDFAVTVFAFLGLIAL---AFNMEPFYFIVV 554
Query: 1318 LRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYF-KC 1376
LR L+ LR Q R V++ + + P + ++ L +IF+ FAI+G++ FA F C
Sbjct: 555 LRPLQLLRLFKIKQRYRNVLDTMFELFPRMASLGLTLIIFYYSFAIVGMEFFADVVFPNC 614
Query: 1377 VDMNHTTLSHEIIPDK--NACTL-ENYTWENSPMNFDHV 1412
+ + S++ + N L E Y + N NF+H+
Sbjct: 615 CNTSTVAESYKQVNKTVGNKTVLEEGYYYLN---NFNHI 650
Score = 61.3 bits (142), Expect = 3e-07
Identities = 41/127 (32%), Positives = 64/127 (50%), Gaps = 7/127 (5%)
Query: 1565 SAVLDYLNMIFIVIFSSECLLKIFALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKY 1623
S ++ + ++F+ I+ E LLKI L YF WNLFDF V +F+ L L+ +
Sbjct: 489 SKIVPWSYIVFLTIYGVEVLLKISGLGPMAYFSSGWNLFDFAVTVFAFLGLIALAFNMEP 548
Query: 1624 FVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFG 1683
F +LR + ++LRL K + R +L + P + ++ L L + + FAI G
Sbjct: 549 FYFIVVLRPL------QLLRLFKIKQRYRNVLDTMFELFPRMASLGLTLIIFYYSFAIVG 602
Query: 1684 MSFFMHV 1690
M FF V
Sbjct: 603 MEFFADV 609
Score = 47.6 bits (108), Expect = 0.003
Identities = 39/154 (25%), Positives = 76/154 (49%), Gaps = 8/154 (5%)
Query: 1219 YFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQK 1278
++ ++T +LL L+L E +P + + ++ + V+ E+ +K LGF
Sbjct: 106 FYMMELLTGLLLMMLSLC-EAPAVPSLRLDVYVHATLELLALVMVAFELCMKLRWLGFHT 164
Query: 1279 YFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMS-RMQG-MRVV 1336
+ + + ++M+ + + L I+ MR RALRP+ + R G +R
Sbjct: 165 FIRHKRTMVKTCVLMLQFVEAIVVL-----IRQTSHMRVTRALRPIFLVDCRYCGAVRRN 219
Query: 1337 VNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
+ + Q++P ++LL+ L F +IFAI+G LF+
Sbjct: 220 LRQIFQSLPPFIDILLLLLFFMVIFAILGFCLFS 253
Score = 41.9 bits (94), Expect = 0.17
Identities = 43/157 (27%), Positives = 68/157 (43%), Gaps = 15/157 (9%)
Query: 1571 LNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLL 1630
L ++ +V+ + E +K+ L +H F+ +V +L L + I + +
Sbjct: 141 LELLALVMVAFELCMKLRWLGFHTFIRHKR----TMVKTCVLMLQFVEAIVVLIRQTSHM 196
Query: 1631 RVVRVAKVGRVLRLV--KGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFM 1688
RV R R + LV + +R L + SLP +I LLL M IFAI G F
Sbjct: 197 RVTRAL---RPIFLVDCRYCGAVRRNLRQIFQSLPPFIDILLLLLFFMVIFAILGFCLF- 252
Query: 1689 HVKDKGGLDDVYNFKTFVQSMILLFQMSTSAGWDGVL 1725
D Y F T S++ LF + T+A + V+
Sbjct: 253 ----SSNSSDPY-FSTLENSLVSLFVLLTTANFPDVM 284
Score = 40.3 bits (90), Expect = 0.52
Identities = 24/122 (19%), Positives = 50/122 (40%), Gaps = 7/122 (5%)
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAY---VTMGIDLGNLAAL 227
++F IY E +K+ G P Y WN DF V A+ + + ++ +
Sbjct: 497 IVFLTIYGVEVLLKISGLG----PMAYFSSGWNLFDFAVTVFAFLGLIALAFNMEPFYFI 552
Query: 228 RTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQ 287
R L+ L+ I + ++ + E + + + + FA++G++ + V+
Sbjct: 553 VVLRPLQLLRLFKIKQRYRNVLDTMFELFPRMASLGLTLIIFYYSFAIVGMEFFADVVFP 612
Query: 288 KC 289
C
Sbjct: 613 NC 614
>UniRef50_Q3HWU6 Cluster: Non L-type Cav channel; n=4;
Strongylocentrotus purpuratus|Rep: Non L-type Cav
channel - Strongylocentrotus purpuratus (Purple sea
urchin)
Length = 217
Score = 63.3 bits (147), Expect = 6e-08
Identities = 36/103 (34%), Positives = 53/103 (51%), Gaps = 8/103 (7%)
Query: 119 NALWILDPFNPIRRVAIYILVHPLFSLFIITTILVNCILMIM--PTTP------TVESTE 170
+AL+I NP+RR YI+ F I+ I ++ I + P P +E +
Sbjct: 110 SALFIFSTTNPVRRFCHYIVTLRYFDTMIMVVIALSSIALAAEDPIDPDNKRNKVLEYFD 169
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALA 213
IFTGI+T E +K+M G +L Y+RD WN LD +V+ A
Sbjct: 170 YIFTGIFTIEMVLKIMDMGLLLHKGAYMRDLWNILDAIVVVCA 212
Score = 54.0 bits (124), Expect = 4e-05
Identities = 33/85 (38%), Positives = 48/85 (56%), Gaps = 5/85 (5%)
Query: 1219 YFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGF-- 1276
YF+T ++ +I LSS+ALA ED P +L Y D IFT IF IEM++K + +G
Sbjct: 133 YFDTMIMVVIALSSIALAAEDPIDPDNK-RNKVLEYFDYIFTGIFTIEMVLKIMDMGLLL 191
Query: 1277 --QKYFTNAWCWLDFIIVMVSLINF 1299
Y + W LD I+V+ +L +
Sbjct: 192 HKGAYMRDLWNILDAIVVVCALFAY 216
Score = 44.0 bits (99), Expect = 0.042
Identities = 29/88 (32%), Positives = 47/88 (53%), Gaps = 6/88 (6%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTL-DHYQQSETFSAVLDYLNMIFIVIFSSECLLKI--F 1588
IVT + FD +IM+ I L+ + + D + VL+Y + IF IF+ E +LKI
Sbjct: 128 IVTLRYFDTMIMVVIALSSIALAAEDPIDPDNKRNKVLEYFDYIFTGIFTIEMVLKIMDM 187
Query: 1589 ALRYH---YFVEPWNLFDFVVVMFSILS 1613
L H Y + WN+ D +VV+ ++ +
Sbjct: 188 GLLLHKGAYMRDLWNILDAIVVVCALFA 215
>UniRef50_UPI00015B4201 Cluster: PREDICTED: similar to two pore
channel 1; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to two pore channel 1 - Nasonia vitripennis
Length = 843
Score = 61.7 bits (143), Expect = 2e-07
Identities = 58/221 (26%), Positives = 98/221 (44%), Gaps = 17/221 (7%)
Query: 1219 YFETAVITMILLSSLALALEDVHLPHRPILQDILY---YMDRIFTVIFFIEMLIKWLALG 1275
YFET V +I+ + +A+ + + L+ + +F +F E L K L LG
Sbjct: 467 YFETLVYGVIIGNGIAMIFRLLQPESDRLRSAHLFAACWDTLLFGGLFAAEALTKVLGLG 526
Query: 1276 FQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQ---G 1332
++Y ++ W D M+ L+ A G+ F + L RPLR + +
Sbjct: 527 VRRYLSSGWNLFDLGTSMMVLV-------AASGLTLFPSAVFLVMFRPLRMLRLFKIKKR 579
Query: 1333 MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDK 1392
R V LV P + + +V L+ + FAI+G++LFAG K N T++
Sbjct: 580 YRDVFGTLVILTPLMCSTAIVMLVLYYFFAIIGMELFAGIDMKNCCKN-TSVEDFYKYSA 638
Query: 1393 NACTLENYTWENSPMNFDHVGKAYLCLFQVATFKGWIQIMN 1433
N T Y + N+ FD++ + + LF++ W +MN
Sbjct: 639 NVTTGLGYYYLNT---FDNLMASGMTLFELTVVNNWFILMN 676
Score = 54.0 bits (124), Expect = 4e-05
Identities = 71/298 (23%), Positives = 134/298 (44%), Gaps = 30/298 (10%)
Query: 1541 IIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVEPW 1599
I M+F +L D + + F+A D L +F +F++E L K+ L Y W
Sbjct: 481 IAMIF---RLLQPESDRLRSAHLFAACWDTL--LFGGLFAAEALTKVLGLGVRRYLSSGW 535
Query: 1600 NLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALA 1659
NLFD S++ LV + + F S L + R R+LRL K K R + L
Sbjct: 536 NLFDLGT---SMMVLVAASGLT-LFPSAVFLVMFRPL---RMLRLFKIKKRYRDVFGTLV 588
Query: 1660 MSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKG-----GLDDVYNFKTFVQSMILLFQ 1714
+ P + + +++ ++ + FAI GM F + K ++D Y + V + + +
Sbjct: 589 ILTPLMCSTAIVMLVLYYFFAIIGMELFAGIDMKNCCKNTSVEDFYKYSANVTTGLGYYY 648
Query: 1715 MSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFL---IVINM 1771
++T +D ++ + E + +N N + T+G+ Y +Y +I +L IV+ +
Sbjct: 649 LNT---FDNLMASGMTLFELTVVNN-WFILMNAYAVTVGM-YTRAYFMIFYLVTMIVLTI 703
Query: 1772 YIAVILENYSQATEDVQEGLTDDDYDMYY-EIWQRFDPDGS---QYIRYDQLSDFLDV 1825
++ LE + + + D+ M + E+ R+D S ++ +Q+ FL +
Sbjct: 704 VVSSFLEAFRFRIQYKRSTTKRDEEKMLHEEVELRYDELESIVQDFLLMEQIRTFLPI 761
Score = 41.5 bits (93), Expect = 0.23
Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 6/123 (4%)
Query: 171 VIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTM-GIDLGNLAA-LR 228
++F G++ E+ KV+ G YL WN D + V G+ L A L
Sbjct: 508 LLFGGLFAAEALTKVLGLGVR----RYLSSGWNLFDLGTSMMVLVAASGLTLFPSAVFLV 563
Query: 229 TFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQK 288
FR LR L+ I + + G ++ + I+ + FA++G++++ G+ +
Sbjct: 564 MFRPLRMLRLFKIKKRYRDVFGTLVILTPLMCSTAIVMLVLYYFFAIIGMELFAGIDMKN 623
Query: 289 CVK 291
C K
Sbjct: 624 CCK 626
Score = 37.1 bits (82), Expect = 4.9
Identities = 36/167 (21%), Positives = 75/167 (44%), Gaps = 15/167 (8%)
Query: 1209 LKTFKLIENT-YFETAVITMILLSSLALALEDVHLPHRPILQDILYY---MDRIFTVIFF 1264
L + L+ N+ Y+ + T ++L LA V P P+ Q ++ ++ +
Sbjct: 124 LPAYLLVHNSWYYGLDLFTALILLGLAF----VEKPAVPLFQLPVWAHGSIELLALTTIG 179
Query: 1265 IEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPL 1324
+E+ +K +G+ + + I + + I + L ++ +R RALRP+
Sbjct: 180 VELALKLRWIGWGTMLKHKRTMVKCITLFIMFIEALIVL-----VRQSSHLRVTRALRPI 234
Query: 1325 RAMSRMQ--GMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF 1369
+ G+R + ++Q +P I ++L + L F L + ++G LF
Sbjct: 235 FLVDTKYCGGVRRFIRQILQTLPPILDMLGLLLFFILTYMVLGYYLF 281
>UniRef50_A4FDR4 Cluster: Voltage-gated sodium channel; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep: Voltage-gated
sodium channel - Saccharopolyspora erythraea (strain NRRL
23338)
Length = 272
Score = 61.3 bits (142), Expect = 3e-07
Identities = 44/158 (27%), Positives = 83/158 (52%), Gaps = 13/158 (8%)
Query: 1214 LIENTYFETAVITMILLSSLALALE-DVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWL 1272
+++ + F+ VI +IL++++AL E L R D L+ +DR +F E+ +
Sbjct: 4 IVDASAFQQVVIGVILVNAVALGAETSPALVER--YGDALHVVDRAALGVFVAELAARLY 61
Query: 1273 ALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQG 1332
A G ++F + W D IV ++L+ A F +R LR +R LR +S +
Sbjct: 62 ARG-ARFFRDPWNCFDATIVGIALLPTTGA---------FGVLRALRIVRALRLISAIPS 111
Query: 1333 MRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFA 1370
MR VV+AL++A+P + ++ + + + A++ +LF+
Sbjct: 112 MRRVVSALLRALPGMASIAALLALILYVAAVIATKLFS 149
Score = 59.3 bits (137), Expect = 1e-06
Identities = 45/202 (22%), Positives = 88/202 (43%), Gaps = 20/202 (9%)
Query: 1532 IVTDKKFDMIIMLFIGLNMLTMTLDHYQQS-ETFSAVLDYLNMIFIVIFSSECLLKIFAL 1590
IV F +++ I +N + + + E + L ++ + +F +E +++A
Sbjct: 4 IVDASAFQQVVIGVILVNAVALGAETSPALVERYGDALHVVDRAALGVFVAELAARLYAR 63
Query: 1591 RYHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKG 1650
+F +PWN FD +V ++L + V+R ++ R LRL+
Sbjct: 64 GARFFRDPWNCFDATIVGIALLP------------TTGAFGVLRALRIVRALRLISAIPS 111
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMI 1710
+R ++ AL +LP + +I LL L++++ A+ F V + F S+
Sbjct: 112 MRRVVSALLRALPGMASIAALLALILYVAAVIATKLFSAVAPE-------YFGDLGGSLF 164
Query: 1711 LLFQMSTSAGWDGVLDGIINEE 1732
LFQ+ T W V ++ E+
Sbjct: 165 TLFQVMTGEAWSEVARAVMAEQ 186
Score = 58.4 bits (135), Expect = 2e-06
Identities = 36/150 (24%), Positives = 73/150 (48%), Gaps = 16/150 (10%)
Query: 143 FSLFIITTILVNCILMIMPTTPTV-----ESTEVI---FTGIYTFESAVKVMARGFILQP 194
F +I ILVN + + T+P + ++ V+ G++ E A ++ ARG
Sbjct: 10 FQQVVIGVILVNAVALGAETSPALVERYGDALHVVDRAALGVFVAELAARLYARGA---- 65
Query: 195 FTYLRDAWNWLDFVVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIE 254
+ RD WN D ++ +A + G LR R++RAL+ ++ +P ++ +V A++
Sbjct: 66 -RFFRDPWNCFDATIVGIALLP---TTGAFGVLRALRIVRALRLISAIPSMRRVVSALLR 121
Query: 255 SVKNLRDVIILTMFSLSVFALMGLQIYMGV 284
++ + + L L V A++ +++ V
Sbjct: 122 ALPGMASIAALLALILYVAAVIATKLFSAV 151
>UniRef50_A1ZWP3 Cluster: Transporter, cation channel family; n=1;
Microscilla marina ATCC 23134|Rep: Transporter, cation
channel family - Microscilla marina ATCC 23134
Length = 270
Score = 60.1 bits (139), Expect = 6e-07
Identities = 45/191 (23%), Positives = 86/191 (45%), Gaps = 11/191 (5%)
Query: 1539 DMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-YFVE 1597
D +I + + +N+L + L + + + +Y+++ + F E ++KI + Y
Sbjct: 20 DRVIFIALQINILVLFLLSFSSLKAEFVIFEYIDLSCTLFFLIEAVVKIKQYSWRGYISS 79
Query: 1598 PWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFA 1657
WN DF++VM + SL++ + F +LR RVAK R L+ + ++ LL
Sbjct: 80 NWNKLDFLIVMLTTPSLLILFLPIPDFTFLLVLRAFRVAKFFRFLQFI---PHLQDLLIG 136
Query: 1658 LAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQMST 1717
+ +L A + L F I ++F F + K F ++ ++F++ T
Sbjct: 137 VGRALKASLFVLLGFFFYNVIVSLFTYYLFREMAPK-------YFTNGFEAFYIIFKIFT 189
Query: 1718 SAGWDGVLDGI 1728
GW + D I
Sbjct: 190 MEGWYDIPDAI 200
Score = 41.5 bits (93), Expect = 0.23
Identities = 30/127 (23%), Positives = 59/127 (46%), Gaps = 3/127 (2%)
Query: 1251 ILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQ 1310
I Y+D T+ F IE ++K ++ Y ++ W LDF+IVM++ + +
Sbjct: 48 IFEYIDLSCTLFFLIEAVVKIKQYSWRGYISSNWNKLDFLIVMLTTPSLLILFLPIPDFT 107
Query: 1311 AFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLF- 1369
+R R + R + + ++ ++ + +A+ + VLL + +I ++ LF
Sbjct: 108 FLLVLRAFRVAKFFRFLQFIPHLQDLLIGVGRALKASLFVLLGFFFYNVIVSLFTYYLFR 167
Query: 1370 --AGKYF 1374
A KYF
Sbjct: 168 EMAPKYF 174
>UniRef50_A7TIJ9 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 835
Score = 60.1 bits (139), Expect = 6e-07
Identities = 87/377 (23%), Positives = 157/377 (41%), Gaps = 53/377 (14%)
Query: 1287 LDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPS 1346
LDFI ++ I + +L G QA + R L LR ++ + + +++ + +P
Sbjct: 478 LDFISIVSYWIGAIISLPGNHNHQASRLFRALSTLRIFSILNIDKEVLIILKGIKLGLPQ 537
Query: 1347 IFNVLLVCLIFWLIFAIMGVQLFAGKYFK-CVDMNHTTLSHEIIPDKNAC-------TLE 1398
+ V + L FW+ F I+GVQ+F G + + CV N T + D C +
Sbjct: 538 LLTVGSMVLYFWIFFGIVGVQIFQGSFSRQCVWTNPTDPNDTYRYDMKFCGGSMGNNSTT 597
Query: 1399 NYTWENSPMNFDHVGKAYL------CLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIY 1452
++ +S F ++ +L C+ + + + N ++S E+ I TN +
Sbjct: 598 KLSYRDSNGIFSNITSGFLCPVNSYCISDINPYNNRVSFDN-LVNSMEL-IFVIMSTNTF 655
Query: 1453 ---MY-----------LYXXXXXXXXXXXTLNLFIGVIIDNFNEQK-----KKAGGSLEM 1493
MY ++ LNL I V++ +F K +K S++
Sbjct: 656 TDLMYYMTEAESLSSSIFFIVTAFIMSIWLLNLLIAVLVSSFESAKSEDRNQKRSNSIKF 715
Query: 1494 FMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAI-VFEIVTDKKFDMIIMLFIGLNMLT 1552
+ K+ + SKK L PRW + I V++I D+II+ I L+++
Sbjct: 716 SLLTFPKRISAFCRTKASKKTL-----PRWSKKLIQVYQIFEWMFVDLIIISLIILSLV- 769
Query: 1553 MTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVMFSIL 1612
QS + + Y+N + I + IF L FV NL+ F++ + +
Sbjct: 770 -------QSSSSMEDISYMNKGNLAINAILLGESIFRL----FVYIPNLWKFIIKLEYVF 818
Query: 1613 SLVLSDIIEKYFVSPTL 1629
L++S I F+S +L
Sbjct: 819 DLLVSVISLATFISASL 835
Score = 52.0 bits (119), Expect = 2e-04
Identities = 58/234 (24%), Positives = 100/234 (42%), Gaps = 29/234 (12%)
Query: 197 YLRDAWNWLDFVVIALAYVTMGIDLG---NLAALRTFRVLRALKTVAIVPGLKTIVGAVI 253
Y+R N LDF+ I ++ I L N A R FR L L+ +I+ K ++ ++
Sbjct: 470 YIRSIKNVLDFISIVSYWIGAIISLPGNHNHQASRLFRALSTLRIFSILNIDKEVL-IIL 528
Query: 254 ESVK----NLRDVIILTMFSLSVFALMGLQIYMGVLTQKCVKVFPEDGSWGNLTDENWER 309
+ +K L V + ++ F ++G+QI+ G +++CV P D N T +
Sbjct: 529 KGIKLGLPQLLTVGSMVLYFWIFFGIVGVQIFQGSFSRQCVWTNPTDP---NDTYRYDMK 585
Query: 310 FC-----QNETNWYGEGGDYPLCGNSSGAGQCEPGYVCLQGFGPNPNYGYTSFDTFGWAF 364
FC N T + N + C C+ P N SFD +
Sbjct: 586 FCGGSMGNNSTTKLSYRDSNGIFSNITSGFLCPVNSYCISDINPYNNR--VSFDNLVNSM 643
Query: 365 LSAFRLM-TQDYWENLY----------QLFFVVIIFLGSFYLVNLILAIVAMSY 407
F +M T + + +Y +FF+V F+ S +L+NL++A++ S+
Sbjct: 644 ELIFVIMSTNTFTDLMYYMTEAESLSSSIFFIVTAFIMSIWLLNLLIAVLVSSF 697
>UniRef50_Q22SA3 Cluster: Cation channel family protein; n=1;
Tetrahymena thermophila SB210|Rep: Cation channel family
protein - Tetrahymena thermophila SB210
Length = 2417
Score = 59.7 bits (138), Expect = 8e-07
Identities = 53/234 (22%), Positives = 107/234 (45%), Gaps = 41/234 (17%)
Query: 1532 IVTDKKFDMIIMLF-IGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL 1590
++ +K++ + L IG +LT+ + Y T S V D+ + F FS E +LKI A
Sbjct: 640 VLEGRKWEALSFLMTIGSCILTILILIYDSLSTDSYV-DFFDKFFFAFFSLEIVLKIVAF 698
Query: 1591 R-YHYFVEPWNLFDFVVVMF-SILSLVLSDIIEKYFV-SPTLLRVVRVAKVGRVLRLVKG 1647
++ EPWN+FD ++V+F + + ++ V S + RV+++AK+ +V R+ +
Sbjct: 699 GPVNFSDEPWNMFDLILVLFQAFFDYIFVTFLKNSNVKSVSASRVLKIAKLQKVFRMFRA 758
Query: 1648 AKGIRTL----------------LFALAMSLPALFNICLLLFLVMFIFAIFGMSFF---- 1687
+ ++ L L+ + + +P + + ++ +V++I+ G+ F
Sbjct: 759 FRTVKVLNYVLSGLDIIRKVYEMLYKIVICIPIVMKLSVIYVIVIYIYTAVGVEIFNTQL 818
Query: 1688 ------------MHVKDKGGLD----DVYNFKTFVQSMILLFQMSTSAGWDGVL 1725
D+G D NF +F + ++L Q+ AGW ++
Sbjct: 819 QTLYPSEYGRALCDQTDEGQTDFNSCQYVNFNSFAGASLILLQVCVGAGWGDIV 872
>UniRef50_Q22N12 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 439
Score = 58.4 bits (135), Expect = 2e-06
Identities = 42/165 (25%), Positives = 81/165 (49%), Gaps = 16/165 (9%)
Query: 1662 LPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDV-YNFKTFVQSMILLFQMSTSAG 1720
LP + I + F ++I+A+FGM+ F +K + L+ +FK F S+ L ++S+
Sbjct: 5 LPQVAPIAAVYFFTIYIYALFGMNLFGFIKPQQTLNGYDLHFKNFTSSVFTLIRISSGEQ 64
Query: 1721 WDGVLDGIINEEE----C-DLPD----NERGSPGNCGSATIGITYLLSYLVISFLIVINM 1771
W ++ + +++ C D+ D E G G CG+ I + +L++S +I+ N+
Sbjct: 65 WFYIVPDVARQQQPNFVCFDVSDFESYQEHGLVG-CGTTWAFIYFFTFHLIVS-VIIFNL 122
Query: 1772 YIAVILENYSQATEDVQEGLTDDDYDMYYEIWQRFDPDGSQYIRY 1816
+IAV+L + ++ E+W+ +D G +I Y
Sbjct: 123 FIAVLL----GLIKTQNTAISKYQLSQIKELWRTYDHQGYGFIDY 163
>UniRef50_UPI0000E45EB7 Cluster: PREDICTED: similar to calcium
channel alpha13.2 subunit, partial; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
calcium channel alpha13.2 subunit, partial -
Strongylocentrotus purpuratus
Length = 401
Score = 58.0 bits (134), Expect = 2e-06
Identities = 35/127 (27%), Positives = 69/127 (54%), Gaps = 7/127 (5%)
Query: 163 TPTVESTEVIFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGID-L 221
T +E + +IFT ++ E +K++A G P Y+ + +N D +++ ++ V + D
Sbjct: 9 TEAIEISNLIFTSLFALEMILKIIAYG----PVGYVSNGFNVFDGLIVIVSVVEVLQDGS 64
Query: 222 GNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIY 281
G L+ LRTFR+LR LK V +P L+ + ++ ++ N+ ++ +L +F +
Sbjct: 65 GGLSVLRTFRLLRILKLVRFMPALRRQLLVMLRTMDNV--ATFFSLLALFIFIFSPGSAF 122
Query: 282 MGVLTQK 288
+LTQ+
Sbjct: 123 GQILTQE 129
Score = 54.0 bits (124), Expect = 4e-05
Identities = 33/110 (30%), Positives = 61/110 (55%), Gaps = 3/110 (2%)
Query: 1248 LQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAG 1307
L + + + IFT +F +EM++K +A G Y +N + D +IV+VS++ + G+G
Sbjct: 8 LTEAIEISNLIFTSLFALEMILKIIAYGPVGYVSNGFNVFDGLIVIVSVVEVLQD--GSG 65
Query: 1308 GIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIF 1357
G+ +T R LR L+ +R M ++ +V+ + + + F+ LL IF
Sbjct: 66 GLSVLRTFRLLRILKLVRFMPALRRQLLVMLRTMDNVATFFS-LLALFIF 114
Score = 42.7 bits (96), Expect = 0.098
Identities = 33/114 (28%), Positives = 59/114 (51%), Gaps = 9/114 (7%)
Query: 1568 LDYLNMIFIVIFSSECLLKIFALR-YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVS 1626
++ N+IF +F+ E +LKI A Y +N+FD ++V+ S++ VL D
Sbjct: 12 IEISNLIFTSLFALEMILKIIAYGPVGYVSNGFNVFDGLIVIVSVVE-VLQD-------G 63
Query: 1627 PTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFA 1680
L V+R ++ R+L+LV+ +R L + ++ + LL L +FIF+
Sbjct: 64 SGGLSVLRTFRLLRILKLVRFMPALRRQLLVMLRTMDNVATFFSLLALFIFIFS 117
>UniRef50_Q4G0N8-2 Cluster: Isoform 2 of Q4G0N8 ; n=4; Catarrhini|Rep:
Isoform 2 of Q4G0N8 - Homo sapiens (Human)
Length = 1129
Score = 58.0 bits (134), Expect = 2e-06
Identities = 33/122 (27%), Positives = 63/122 (51%), Gaps = 3/122 (2%)
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSET-FSAVLDYLNMIFIVIFSSECLLK 1586
I IV ++F+ + L I +N+ + Q + + L + N F+ ++ E LLK
Sbjct: 555 ICHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLK 614
Query: 1587 IFALRYHYFVEPWNLFDFVVVMFSILSLVLSDI--IEKYFVSPTLLRVVRVAKVGRVLRL 1644
I A+R +F WN+F+ + + IL ++L +I I+ F ++ ++V + R+LR+
Sbjct: 615 IAAMRKDFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRI 674
Query: 1645 VK 1646
K
Sbjct: 675 FK 676
>UniRef50_Q4G0N8 Cluster: Sodium/hydrogen exchanger 10 (Na(+)/H(+)
exchanger 10) (Sperm-specific Na(+)/H(+) exchanger);
n=18; Theria|Rep: Sodium/hydrogen exchanger 10
(Na(+)/H(+) exchanger 10) (Sperm-specific Na(+)/H(+)
exchanger) - Homo sapiens (Human)
Length = 1177
Score = 58.0 bits (134), Expect = 2e-06
Identities = 33/122 (27%), Positives = 63/122 (51%), Gaps = 3/122 (2%)
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSET-FSAVLDYLNMIFIVIFSSECLLK 1586
I IV ++F+ + L I +N+ + Q + + L + N F+ ++ E LLK
Sbjct: 603 ICHTIVFTEEFEHVGYLVILMNIFPFIISWISQLNVIYHSELKHTNYCFLTLYILEALLK 662
Query: 1587 IFALRYHYFVEPWNLFDFVVVMFSILSLVLSDI--IEKYFVSPTLLRVVRVAKVGRVLRL 1644
I A+R +F WN+F+ + + IL ++L +I I+ F ++ ++V + R+LR+
Sbjct: 663 IAAMRKDFFSHAWNIFELAITLIGILHVILIEIDTIKYIFNETEVIVFIKVVQFFRILRI 722
Query: 1645 VK 1646
K
Sbjct: 723 FK 724
>UniRef50_A3RL54 Cluster: Sperm-specific sodium proton exchanger; n=3;
Strongylocentrotus purpuratus|Rep: Sperm-specific sodium
proton exchanger - Strongylocentrotus purpuratus (Purple
sea urchin)
Length = 1325
Score = 57.2 bits (132), Expect = 4e-06
Identities = 38/165 (23%), Positives = 85/165 (51%), Gaps = 24/165 (14%)
Query: 1511 SKKPLKAIPRPRWRPQAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSA---- 1566
S+K + AIP P+++ ++++I F++ I + I LN++ + ++ Q + S
Sbjct: 653 SEKKIAAIPMPKYKLGKLMYKICHHMAFEVTINIAIVLNIVPIIMEFVVQDKMASVSTMA 712
Query: 1567 ------------------VLDYLNMIFIVIFSSECLLKIFALRYHYFVEPWNLFDFVVVM 1608
L N +F VI++ E ++KI L HY V WN FD +++
Sbjct: 713 APGSTVSSEPSSLQKIEDALRISNYVFFVIYAIEAIVKILGLGRHYIVSHWNKFDAFILV 772
Query: 1609 FSILSLVLSDIIEKYFVSPTL--LRVVRVAKVGRVLRLVKGAKGI 1651
+++ +++++ + K ++ L ++VV++ ++ R LR+++ K +
Sbjct: 773 VALVDIIIAETLLKGSITINLSSIKVVKLFRLLRGLRMLRLTKAL 817
>UniRef50_UPI0000E4A226 Cluster: PREDICTED: similar to four
domain-type voltage-gated ion channel alpha-1 subunit;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to four domain-type voltage-gated ion channel
alpha-1 subunit - Strongylocentrotus purpuratus
Length = 1324
Score = 56.4 bits (130), Expect = 7e-06
Identities = 39/146 (26%), Positives = 72/146 (49%), Gaps = 5/146 (3%)
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMI 1710
++ L+ + +S F I + LFL++ +A G+ F VK L NF+ +M
Sbjct: 91 LKMLMMTIVVSCGKSFFIIVGLFLLITFYAFLGVVLFGKVKYGEHLGRHANFENAPNAMA 150
Query: 1711 LLFQMSTSAGWDGVL-DGIINEEECDLPDNERGSPGNCGSATIGITYLLSYLVISFLIVI 1769
LF++ T W+ ++ D +I+E C E +CG++ + Y S+ V+ IVI
Sbjct: 151 TLFRIVTGEDWNKIMHDCMISEPHCS-KRGENYWETDCGNSIASMVYFCSFYVLIAYIVI 209
Query: 1770 NMYIAVILENYSQATEDVQEGLTDDD 1795
N+ + +L S + D+++ L D+
Sbjct: 210 NLLVGSML---SYRSVDIRKSLQLDE 232
Score = 40.7 bits (91), Expect = 0.40
Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 9/98 (9%)
Query: 834 RVFKLAKSWPTLNLLISIMGRTMGALGNLTFVLCIIIFIFAVMGMQLFGK-NYVDYVDRF 892
R F + PTL +L+ + + G + L ++I +A +G+ LFGK Y +++ R
Sbjct: 80 RFFTITGKHPTLKMLMMTIVVSCGKSFFIIVGLFLLITFYAFLGVVLFGKVKYGEHLGRH 139
Query: 893 PDGDLPRWNFTDFMHSFMIVFRVLCGE-WIESMWDCML 929
NF + ++ +FR++ GE W + M DCM+
Sbjct: 140 A-------NFENAPNAMATLFRIVTGEDWNKIMHDCMI 170
>UniRef50_UPI0000E4670D Cluster: PREDICTED: similar to
voltage-dependent T-type calcium channel alpha-1 subunit;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to voltage-dependent T-type calcium channel
alpha-1 subunit - Strongylocentrotus purpuratus
Length = 1181
Score = 55.6 bits (128), Expect = 1e-05
Identities = 46/211 (21%), Positives = 96/211 (45%), Gaps = 17/211 (8%)
Query: 1526 QAIVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLL 1585
Q+ +I+ + I++ I L+ + L + ET + L + IF+ E LL
Sbjct: 542 QSFSQKIIRSSVYSKILLALILLHSILFCLRWHNMDETARITIQVLKTTILAIFAVEVLL 601
Query: 1586 KIFALRYHYFVEPWNLFDFVVVMFSILSLV-LSDIIEKYFVSPTLLRVVRVAKVGRV-LR 1643
+I + E NL V ++ IL ++ ++ I YF+ T + + V R
Sbjct: 602 RIMS-------EGKNLMQVVEILDIILIVIGVTSNIPIYFIPRTYFGLCNIISGLAVSFR 654
Query: 1644 L-VKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDD-VYN 1701
L A+ + ++ P +F++ +L+F+++F ++ G F + D VY+
Sbjct: 655 LGFNSAQAKKVVILFSTKVFPVMFDLIILVFIIIFFASVLGWELFYGITADTSYDTGVYD 714
Query: 1702 ------FKTFVQSMILLFQMSTSAGWDGVLD 1726
F +F S++++FQ+ T++ W +++
Sbjct: 715 YNCGIGFNSFSCSLLMVFQIVTTSNWHEIMN 745
>UniRef50_Q6TMY6 Cluster: Putative voltage-gated cation channel
subunit; n=2; Vibrio vulnificus|Rep: Putative
voltage-gated cation channel subunit - Vibrio vulnificus
Length = 259
Score = 53.6 bits (123), Expect = 5e-05
Identities = 45/194 (23%), Positives = 89/194 (45%), Gaps = 20/194 (10%)
Query: 1536 KKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFALRYH-Y 1594
K D + + ++L H ++ F Y+++ ++ FS E L++ L + Y
Sbjct: 12 KSLDRLSSYVVISSLLVFFTQHLYENHIFQ----YIDICVLIYFSLEFFLRVHVLSWKKY 67
Query: 1595 FVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTL 1654
F P FDF +++ S++++ +S+I + LRV R+ V RV ++V +
Sbjct: 68 FQSPSCQFDFFLLVVSLVAIPISNIDSVIY-----LRVFRLISVIRVFKIVPNGSQV--- 119
Query: 1655 LFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMILLFQ 1714
L LA ++ + + +LLF ++ F++ G F + F T + S+ +F+
Sbjct: 120 LSGLARAIKSSKAVLILLFCLLCFFSLIGFILFSSSVPE-------YFSTPLTSLNTVFE 172
Query: 1715 MSTSAGWDGVLDGI 1728
+ T W + D I
Sbjct: 173 IFTIENWGALPDSI 186
Score = 48.0 bits (109), Expect = 0.003
Identities = 37/143 (25%), Positives = 67/143 (46%), Gaps = 10/143 (6%)
Query: 1228 ILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWL 1287
+++SSL L HL I Q Y+D + F +E ++ L ++KYF + C
Sbjct: 21 VVISSL-LVFFTQHLYENHIFQ----YIDICVLIYFSLEFFLRVHVLSWKKYFQSPSCQF 75
Query: 1288 DFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSI 1347
DF +++VSL+ + I + +R R + +R + V++ L +AI S
Sbjct: 76 DFFLLVVSLVAIPIS-----NIDSVIYLRVFRLISVIRVFKIVPNGSQVLSGLARAIKSS 130
Query: 1348 FNVLLVCLIFWLIFAIMGVQLFA 1370
VL++ F+++G LF+
Sbjct: 131 KAVLILLFCLLCFFSLIGFILFS 153
Score = 39.9 bits (89), Expect = 0.69
Identities = 19/77 (24%), Positives = 44/77 (57%), Gaps = 1/77 (1%)
Query: 206 DFVVIALAYVTMGI-DLGNLAALRTFRVLRALKTVAIVPGLKTIVGAVIESVKNLRDVII 264
DF ++ ++ V + I ++ ++ LR FR++ ++ IVP ++ + ++K+ + V+I
Sbjct: 76 DFFLLVVSLVAIPISNIDSVIYLRVFRLISVIRVFKIVPNGSQVLSGLARAIKSSKAVLI 135
Query: 265 LTMFSLSVFALMGLQIY 281
L L F+L+G ++
Sbjct: 136 LLFCLLCFFSLIGFILF 152
>UniRef50_Q14721 Cluster: Potassium voltage-gated channel subfamily B
member 1; n=23; Euteleostomi|Rep: Potassium voltage-gated
channel subfamily B member 1 - Homo sapiens (Human)
Length = 858
Score = 53.6 bits (123), Expect = 5e-05
Identities = 62/254 (24%), Positives = 118/254 (46%), Gaps = 19/254 (7%)
Query: 1478 DNFNEQKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKPLKAIPRPRWRPQAIVFEIVTDKK 1537
+ NE+ K+ +L + +++ N KK + +P A + I++
Sbjct: 142 EQMNEELKREAETLR---EREGEEFDNTCCAEKRKKLWDLLEKPNSSVAAKILAIISIM- 197
Query: 1538 FDMIIMLFIGLNMLT--MTLDHYQQSETFSAVLDYLNMIFIVIFSSECLLKIFAL--RYH 1593
F ++ + + LN L +LD + QS T + L ++ + I F+ E LL+ + ++
Sbjct: 198 FIVLSTIALSLNTLPELQSLDEFGQS-TDNPQLAHVEAVCIAWFTMEYLLRFLSSPKKWK 256
Query: 1594 YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVKGAK---G 1650
+F P N D + ++ +++ L++ + + RVV++ ++ R+LR++K A+ G
Sbjct: 257 FFKGPLNAIDLLAILPYYVTIFLTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTG 316
Query: 1651 IRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDVYNFKTFVQSMI 1710
+++L F L S L L+LFL M I IF F KD+ DD FK+ S
Sbjct: 317 LQSLGFTLRRSYNELG--LLILFLAMGIM-IFSSLVFFAEKDE---DDT-KFKSIPASFW 369
Query: 1711 LLFQMSTSAGWDGV 1724
T+ G+ +
Sbjct: 370 WATITMTTVGYGDI 383
>UniRef50_UPI0000ECC6B0 Cluster: UPI0000ECC6B0 related cluster; n=1;
Gallus gallus|Rep: UPI0000ECC6B0 UniRef100 entry - Gallus
gallus
Length = 569
Score = 52.0 bits (119), Expect = 2e-04
Identities = 45/184 (24%), Positives = 85/184 (46%), Gaps = 10/184 (5%)
Query: 1191 FLAGDDDSPF--WQGWGTLRLKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPIL 1248
F+A D++SP+ + W L L +++ + T+I+ ++L + + L
Sbjct: 287 FIALDEESPYISYAEWIFLALYIIEILLKFVKKLKFDTLIIFAALTATILNTTLKSSKCS 346
Query: 1249 QDILYYMDRIFTVIFFIEMLIKWLALGFQKYFTNAWCWLDFIIVMVSLINFVAALCGAGG 1308
L+ R+ F + I L L F K T L F+++ F+ +
Sbjct: 347 LSSLHASGRLSG--FELSFAIV-LVLVFNKDIT-----LTFLLIFQKTNLFLFSATKYNS 398
Query: 1309 IQAFKTMRTLRALRPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQL 1368
+ + LR LR +R + +Q RV++N L+ +P++ + L+ + IFAI+G++L
Sbjct: 399 QRILDIVFILRVLRLIRIVDSIQRFRVIMNTLINIVPTMLTFGGLTLVVYCIFAIIGMEL 458
Query: 1369 FAGK 1372
F GK
Sbjct: 459 FHGK 462
>UniRef50_UPI0000E46611 Cluster: PREDICTED: similar to putative four
repeat ion channel, partial; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to putative four
repeat ion channel, partial - Strongylocentrotus
purpuratus
Length = 666
Score = 51.2 bits (117), Expect = 3e-04
Identities = 102/510 (20%), Positives = 204/510 (40%), Gaps = 73/510 (14%)
Query: 1246 PILQDILYYMDRIFTVIFFIEMLIKW----LALGFQKYFTNAWCWLDFIIVMVSLINFVA 1301
P ++ + +D + T++FF E + K + G Y + W D +V+ ++ +
Sbjct: 69 PSMEYMTLVVDSVVTLLFFSETIFKMTTRGIIFGEYAYLRDNWGRFDTSMVLSLWVSILL 128
Query: 1302 ALCGAGGIQAFKTMRT-LRALRPLRAMS--RMQGMRVVVNALVQAI-----PSIFNVLLV 1353
+C + T T LRA RP + R+ + A V++I +++V +
Sbjct: 129 QICQIANVVPKYTPYTILRAPRPFIMIRSFRVYLKFKLPKARVKSIFKRSGQQVWSVTIF 188
Query: 1354 CLIFWLIFAIMGVQLFAGKYFKCVDMNHTTLSHEIIPDKNACTLENYTWENSPMNFDHVG 1413
+ F +++ ++GVQ+F CV ++N T+ F+ +
Sbjct: 189 LVFFLVLYGMLGVQMFGDLSTHCVKKE----------------IDNQTFSAVHSIFNKIC 232
Query: 1414 KAYLCLFQVATFKGWIQIMNDAIDSREVGRQPIRETNIYMYLYXXXXXXXXXXXTLNLFI 1473
+ +++ A+ +GW+ IM DS R Y + N+FI
Sbjct: 233 VSIFTVYESASLEGWVFIMYKVTDSFPSWRG---------YFFFITMIFFLAWLVKNVFI 283
Query: 1474 GVIIDNFNE------QKKKAGGSLEMFMTEDQKKYYNAMKKMGSKKP--LKAIPRPRWRP 1525
VII+ F E Q GG+ + F D K ++ G+ P L + R
Sbjct: 284 AVIIETFAEIRVQFRQMWTRGGAAQSF---DSK--VEVLQDDGTYTPWKLTIVDENNSRG 338
Query: 1526 QAIVF--EIVTDKKFDMIIMLFIGLN-MLTMTL-----DHYQQSETFSAVLDYLNMIFIV 1577
A + ++ + I+ + ++ +L T D+ + L + F +
Sbjct: 339 PAPMCCQRVLESRSCHFFILGMVAIDAVLASTYNMFYPDNEDLKNRYHKGLYIAQVGFTL 398
Query: 1578 IFSSECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVA 1636
+F E L K++ L + YF + F+ + + + S+ + D E+ + S L +V
Sbjct: 399 LFDVEVLFKVWCLGFRGYFKRSLHKFELCLAIGN--SIRIMD-PERLYSSQ--LAYFQVM 453
Query: 1637 KVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGL 1696
+ R+++L + +F + L L L + + ++ + F +V
Sbjct: 454 RCFRLIKLSPTLEDFSRKIFGPFIKLGTLI---LFTMSSLILVSVISLQLFCYV------ 504
Query: 1697 DDVYNFKTFVQSMILLFQMSTSAGWDGVLD 1726
+D+ F TF +++ +FQ+ T GW V+D
Sbjct: 505 EDLKQFDTFPTAVMSVFQILTQEGWIEVVD 534
Score = 39.5 bits (88), Expect = 0.91
Identities = 30/134 (22%), Positives = 66/134 (49%), Gaps = 15/134 (11%)
Query: 172 IFTGIYTFESAVKVMARGFILQPFTYLRDAWNWLDFVVIALAYVTMGIDLGNLAAL---- 227
+ T ++ E+ K+ RG I + YLRD W D ++ +V++ + + +A +
Sbjct: 81 VVTLLFFSETIFKMTTRGIIFGEYAYLRDNWGRFDTSMVLSLWVSILLQICQIANVVPKY 140
Query: 228 RTFRVLRALKTVAIVPGLKT-----IVGAVIESV-----KNLRDVIILTMFSLSVFALMG 277
+ +LRA + ++ + + A ++S+ + + V I +F L ++ ++G
Sbjct: 141 TPYTILRAPRPFIMIRSFRVYLKFKLPKARVKSIFKRSGQQVWSVTIFLVFFLVLYGMLG 200
Query: 278 LQIYMGVLTQKCVK 291
+Q++ G L+ CVK
Sbjct: 201 VQMF-GDLSTHCVK 213
>UniRef50_Q23RF4 Cluster: Cation channel family protein; n=1;
Tetrahymena thermophila SB210|Rep: Cation channel family
protein - Tetrahymena thermophila SB210
Length = 1736
Score = 51.2 bits (117), Expect = 3e-04
Identities = 32/154 (20%), Positives = 76/154 (49%), Gaps = 12/154 (7%)
Query: 1213 KLIENTYFETAVITMILLSSLAL---ALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLI 1269
K+ + Y+ ++ ++ +++AL + V+ + L DI ++ F ++ ++ I
Sbjct: 503 KISRSHYWSYFILFIVFSNTIALIYYSAATVYTDNSSSLDDIYTNIEIFFLSVYITDVCI 562
Query: 1270 KWLALGFQKYFTNAWCWLDFIIVMVSLIN--------FVAALCGAGGIQAFKTMRTLRAL 1321
K + LG +YF + W DF + +VSL+ F+ I+ K R L+
Sbjct: 563 KMIGLGINEYFDDYWNNFDFFMAIVSLVTIIGLKYIYFIKETKSTKLIKITKLQRVLKIF 622
Query: 1322 RPLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCL 1355
R +R++ + +++ +AL++ + +F+ + +C+
Sbjct: 623 RSIRSIKLLSFLKLGADALLR-VQKLFHKIAICI 655
Score = 50.8 bits (116), Expect = 4e-04
Identities = 45/188 (23%), Positives = 97/188 (51%), Gaps = 15/188 (7%)
Query: 1528 IVFEIVTDKKFDMIIMLFIGLNMLTMTLDHYQQSETF---SAVLD--YLNM--IFIVIFS 1580
+ FE ++ + +LFI + T+ L +Y + + S+ LD Y N+ F+ ++
Sbjct: 499 LYFEKISRSHYWSYFILFIVFSN-TIALIYYSAATVYTDNSSSLDDIYTNIEIFFLSVYI 557
Query: 1581 SECLLKIFALRYH-YFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPT-LLRVVRVAKV 1638
++ +K+ L + YF + WN FDF + + S+++++ I YF+ T +++++ K+
Sbjct: 558 TDVCIKMIGLGINEYFDDYWNNFDFFMAIVSLVTIIGLKYI--YFIKETKSTKLIKITKL 615
Query: 1639 GRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLF-LVMFIFAIFG-MSFFMHVKDKGGL 1696
RVL++ + + I+ L F L + AL + L + + I +++G +S + + G
Sbjct: 616 QRVLKIFRSIRSIKLLSF-LKLGADALLRVQKLFHKIAICIPSVWGFVSTYFLISISYGF 674
Query: 1697 DDVYNFKT 1704
++ F T
Sbjct: 675 LGIFLFNT 682
>UniRef50_Q12VA9 Cluster: Ion transport protein; n=2; cellular
organisms|Rep: Ion transport protein - Methanococcoides
burtonii (strain DSM 6242)
Length = 292
Score = 51.2 bits (117), Expect = 3e-04
Identities = 42/155 (27%), Positives = 79/155 (50%), Gaps = 9/155 (5%)
Query: 1219 YFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEMLIKWLALGFQ- 1277
YF+ +I I+LS + + L+ VH I LY + IFT++F IE L++ + + +
Sbjct: 36 YFDITLILTIILSVIVVMLDSVH-SISSIHHQKLYMAEIIFTILFTIEYLLRMICVKSKV 94
Query: 1278 KYFTNAWCWLDFIIVMVSLINFVAALCGAGGIQAFKTMRTLRALRPLRAMSRMQGMRVVV 1337
+Y T+ + +D + ++ + ++F G+ + + R LR R L+ + + ++V
Sbjct: 95 RYATSFFGIIDLLAIIPTYLSFF--FPGSQYLLIIRVFRLLRIFRVLKLVQYLTEADMLV 152
Query: 1338 NALVQAIPSI----FNVL-LVCLIFWLIFAIMGVQ 1367
AL + I F VL LV ++ L++ I G Q
Sbjct: 153 QALKDSSKKITVFTFTVLNLVLILGSLMYVIEGEQ 187
Score = 41.5 bits (93), Expect = 0.23
Identities = 41/176 (23%), Positives = 83/176 (47%), Gaps = 13/176 (7%)
Query: 1529 VFEIVTD--KKFDMIIMLFIGLNMLTMTLDHYQQSETFSAVLDYL-NMIFIVIFSSECLL 1585
+FE T K FD+ ++L I L+++ + LD + Y+ +IF ++F+ E LL
Sbjct: 26 IFEANTPIGKYFDITLILTIILSVIVVMLDSVHSISSIHHQKLYMAEIIFTILFTIEYLL 85
Query: 1586 KIFALR--YHYFVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLR 1643
++ ++ Y + + D + ++ + LS +Y + ++RV R+ ++ RVL+
Sbjct: 86 RMICVKSKVRYATSFFGIIDLLAIIPTYLSFFFPG--SQYLL---IIRVFRLLRIFRVLK 140
Query: 1644 LVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGGLDDV 1699
LV+ L+ AL S I + F V+ + I G ++ ++ G +
Sbjct: 141 LVQYLTEADMLVQALKDSSK---KITVFTFTVLNLVLILGSLMYVIEGEQNGFTSI 193
>UniRef50_Q5QM84 Cluster: Two pore calcium channel protein 1; n=16;
Embryophyta|Rep: Two pore calcium channel protein 1 -
Oryza sativa subsp. japonica (Rice)
Length = 757
Score = 51.2 bits (117), Expect = 3e-04
Identities = 57/273 (20%), Positives = 117/273 (42%), Gaps = 33/273 (12%)
Query: 1538 FDMIIMLFIGLNMLTMTLDHYQQSETFSA--VLDYLNMIFIVIFSSECLLKIFALRYH-Y 1594
F+ I++ + +N++ + ++ E S+ V + +F I+ E LKIF+L + Y
Sbjct: 457 FEYIVIFVLLMNLVAVIIETTLDIENSSSQKVWQEVEFVFGWIYVIEMALKIFSLGFGAY 516
Query: 1595 FVEPWNLFDFVVVMFSILSLVLSDIIEKYFVSPTLLRVVRVAKVGRVLRLVK---GAKGI 1651
++E N FDFV+ + L+ + +R +GR+LRL + +
Sbjct: 517 WMEGQNKFDFVLTWTIFIGETLTFAFPSKLSFLSNGEWIRYLLLGRMLRLTRILLQVRRF 576
Query: 1652 RTLLFALAMSLPALFNICLLLFLVMFIFAIFGMSFFMHVKDKGG--LDD---------VY 1700
R + + +L ++F + I+ G+ F + G L++ ++
Sbjct: 577 RAFVATFFTLMSSLMPYLGIVFCTLCIYCSLGLQIFGGIVYAGNPTLEETDLFSNDYLLF 636
Query: 1701 NFKTFVQSMILLFQMSTSAGWDGVLDGIINEEECDLPDNERGSPGNCGSATIGITYLLSY 1760
NF + M+ LF + W + ++ R G+ S + Y +S+
Sbjct: 637 NFNDYPSGMVTLFNLLVMGNWQAWM------------ESYRQLTGSYWS----LIYFVSF 680
Query: 1761 LVISFLIVINMYIAVILENYSQATEDVQEGLTD 1793
+IS L+++N+ +A +LE + E ++G D
Sbjct: 681 YLISVLLLLNLIVAFVLEAFFAEMELEKDGEAD 713
Score = 46.0 bits (104), Expect = 0.011
Identities = 39/169 (23%), Positives = 74/169 (43%), Gaps = 8/169 (4%)
Query: 1209 LKTFKLIENTYFETAVITMILLSSLALALEDVHLPHRPILQDILYYMDRIFTVIFFIEML 1268
LK+F + + FE VI ++L++ +A+ +E Q + ++ +F I+ IEM
Sbjct: 448 LKSF--VRSPLFEYIVIFVLLMNLVAVIIETTLDIENSSSQKVWQEVEFVFGWIYVIEMA 505
Query: 1269 IKWLALGFQKYFTNAWCWLDFIIVMVSLIN------FVAALCGAGGIQAFKTMRTLRALR 1322
+K +LGF Y+ DF++ I F + L + + + R LR
Sbjct: 506 LKIFSLGFGAYWMEGQNKFDFVLTWTIFIGETLTFAFPSKLSFLSNGEWIRYLLLGRMLR 565
Query: 1323 PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAG 1371
R + +++ R V + S+ L + I+ +G+Q+F G
Sbjct: 566 LTRILLQVRRFRAFVATFFTLMSSLMPYLGIVFCTLCIYCSLGLQIFGG 614
Score = 43.2 bits (97), Expect = 0.074
Identities = 40/166 (24%), Positives = 74/166 (44%), Gaps = 25/166 (15%)
Query: 141 PLFSLFIITTILVNCILMIMPTTPTVEST---------EVIFTGIYTFESAVKVMARGFI 191
PLF +I +L+N + +I+ TT +E++ E +F IY E A+K+ + GF
Sbjct: 455 PLFEYIVIFVLLMNLVAVIIETTLDIENSSSQKVWQEVEFVFGWIYVIEMALKIFSLGF- 513
Query: 192 LQPFTYLRDAWNWLDFVV---------IALAYVTMGIDLGN---LAALRTFRVLRALKTV 239
Y + N DFV+ + A+ + L N + L R+LR + +
Sbjct: 514 ---GAYWMEGQNKFDFVLTWTIFIGETLTFAFPSKLSFLSNGEWIRYLLLGRMLRLTRIL 570
Query: 240 AIVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVL 285
V + V + +L + + +L ++ +GLQI+ G++
Sbjct: 571 LQVRRFRAFVATFFTLMSSLMPYLGIVFCTLCIYCSLGLQIFGGIV 616
Score = 37.9 bits (84), Expect = 2.8
Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 10/65 (15%)
Query: 353 GYTSFDTFGWAFLSAFRLMTQ----DYWENLYQ------LFFVVIIFLGSFYLVNLILAI 402
G T F ++G F L T D W Y+ LFF+V + LG ++L NLILA+
Sbjct: 269 GKTVFSSYGTTLYQMFILFTTSNNPDVWVPAYKSSRWSSLFFIVYVLLGVYFLTNLILAV 328
Query: 403 VAMSY 407
+ S+
Sbjct: 329 IYDSF 333
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.324 0.140 0.428
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,984,929,194
Number of Sequences: 1657284
Number of extensions: 81365796
Number of successful extensions: 265712
Number of sequences better than 10.0: 358
Number of HSP's better than 10.0 without gapping: 258
Number of HSP's successfully gapped in prelim test: 100
Number of HSP's that attempted gapping in prelim test: 258084
Number of HSP's gapped (non-prelim): 4221
length of query: 1969
length of database: 575,637,011
effective HSP length: 112
effective length of query: 1857
effective length of database: 390,021,203
effective search space: 724269373971
effective search space used: 724269373971
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.6 bits)
S2: 80 (36.3 bits)
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