Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001550-TA|BGIBMGA001550-PA|IPR000719|Protein kinase,
IPR011009|Protein kinase-like, IPR001245|Tyrosine protein kinase,
IPR002290|Serine/threonine protein kinase
(338 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X79193-1|CAA55785.1| 346|Homo sapiens MO15/CDK-activating kinas... 482 e-136
X77743-1|CAA54793.1| 346|Homo sapiens CDK activating kinase pro... 482 e-136
X77303-1|CAA54508.1| 346|Homo sapiens Cdk-activating kinase pro... 482 e-136
L20320-1|AAA36657.1| 346|Homo sapiens protein serine/threonine ... 482 e-136
BC000834-1|AAH00834.1| 346|Homo sapiens cyclin-dependent kinase... 482 e-136
AY130859-1|AAM77799.1| 346|Homo sapiens cyclin-dependent kinase... 482 e-136
BC005298-1|AAH05298.1| 346|Homo sapiens cyclin-dependent kinase... 481 e-135
Y13120-1|CAA73587.1| 346|Homo sapiens serine/threonine protein ... 479 e-135
X61622-1|CAA43807.1| 298|Homo sapiens CDK2 protein. 256 8e-68
X66364-1|CAA47007.1| 292|Homo sapiens serine/threonine protein ... 256 1e-67
M68520-1|AAA35667.1| 298|Homo sapiens cdc2-related protein kina... 256 1e-67
BT006821-1|AAP35467.1| 298|Homo sapiens cyclin-dependent kinase... 256 1e-67
BT006680-1|AAP35326.1| 292|Homo sapiens cyclin-dependent kinase... 256 1e-67
BC005115-1|AAH05115.1| 292|Homo sapiens cyclin-dependent kinase... 256 1e-67
BC003065-1|AAH03065.1| 298|Homo sapiens cyclin-dependent kinase... 256 1e-67
AY049778-1|AAL15435.1| 292|Homo sapiens cyclin-dependent kinase... 256 1e-67
AF512553-1|AAM34794.1| 298|Homo sapiens cyclin-dependent kinase... 256 1e-67
X66357-1|CAA47001.1| 305|Homo sapiens serine/threonine protein ... 254 2e-67
X62071-1|CAA43985.1| 298|Homo sapiens cdk2 protein. 254 2e-67
AY789470-1|AAV40830.1| 305|Homo sapiens cyclin-dependent kinase... 254 2e-67
CR457041-1|CAG33322.1| 292|Homo sapiens CDK5 protein. 253 8e-67
BC110905-1|AAI10906.1| 397|Homo sapiens cell division cycle 2-l... 246 1e-64
BC094827-1|AAH94827.1| 475|Homo sapiens CDC2L2 protein protein. 246 1e-64
BC014464-1|AAH14464.1| 464|Homo sapiens CDC2L2 protein protein. 246 1e-64
AL031282-7|CAI20032.1| 783|Homo sapiens cell division cycle 2-l... 246 1e-64
AL031282-6|CAI20034.1| 780|Homo sapiens cell division cycle 2-l... 246 1e-64
AL031282-5|CAI20031.1| 779|Homo sapiens cell division cycle 2-l... 246 1e-64
AL031282-4|CAI20033.1| 770|Homo sapiens cell division cycle 2-l... 246 1e-64
AL031282-3|CAI20030.1| 746|Homo sapiens cell division cycle 2-l... 246 1e-64
AF080694-4|AAC95300.1| 768|Homo sapiens PITSLRE protein kinase ... 246 1e-64
AF080694-3|AAC95298.1| 781|Homo sapiens PITSLRE protein kinase ... 246 1e-64
AF080694-2|AAC95297.1| 777|Homo sapiens PITSLRE protein kinase ... 246 1e-64
AF080694-1|AAC95299.1| 778|Homo sapiens PITSLRE protein kinase ... 246 1e-64
AF067523-1|AAC72088.1| 397|Homo sapiens PITSLRE protein kinase ... 246 1e-64
AF067522-1|AAC72087.1| 780|Homo sapiens PITSLRE protein kinase ... 246 1e-64
AF067521-1|AAC72086.1| 767|Homo sapiens PITSLRE protein kinase ... 246 1e-64
AF067520-1|AAC72085.1| 776|Homo sapiens PITSLRE protein kinase ... 246 1e-64
AF067519-1|AAC72084.1| 777|Homo sapiens PITSLRE protein kinase ... 246 1e-64
AF067518-1|AAC72083.1| 397|Homo sapiens PITSLRE protein kinase ... 246 1e-64
U07705-1|AAA19595.1| 775|Homo sapiens PITSLRE isoform PBETA22 p... 245 2e-64
U07704-1|AAA19594.1| 777|Homo sapiens PITSLRE isoform PBETA21 p... 245 2e-64
U04824-1|AAA19586.1| 779|Homo sapiens PITSLRE alpha 2-1 protein. 245 2e-64
U04819-1|AAA19585.1| 439|Homo sapiens PITSLRE beta 1 protein. 245 2e-64
U04818-1|AAA19584.1| 562|Homo sapiens PITSLRE alpha 2-4 protein. 245 2e-64
U04817-1|AAA19583.1| 768|Homo sapiens PITSLRE alpha 2-3 protein. 245 2e-64
U04816-1|AAA19582.1| 777|Homo sapiens PITSLRE alpha 2-2 protein. 245 2e-64
U04815-1|AAA19581.1| 461|Homo sapiens PITSLRE alpha 1 protein. 245 2e-64
M88563-1|AAB59449.1| 446|Homo sapiens p58 protein kinase protein. 245 2e-64
M37712-1|AAA36406.1| 439|Homo sapiens p58/GTA protein kinase pr... 244 3e-64
BC139777-1|AAI39778.1| 542|Homo sapiens CDC2L1 protein protein. 244 3e-64
BC062579-1|AAH62579.1| 475|Homo sapiens CDC2L1 protein protein. 244 3e-64
BC033069-1|AAH33069.1| 508|Homo sapiens CDC2L1 protein protein. 244 3e-64
AF080683-5|AAC83666.1| 565|Homo sapiens PITSLRE protein kinase ... 244 3e-64
AF080683-4|AAC83663.1| 738|Homo sapiens PITSLRE protein kinase ... 244 3e-64
AF080683-3|AAC83665.1| 748|Homo sapiens PITSLRE protein kinase ... 244 3e-64
AF080683-2|AAC83662.1| 782|Homo sapiens PITSLRE protein kinase ... 244 3e-64
AF080683-1|AAC83664.1| 755|Homo sapiens PITSLRE protein kinase ... 244 3e-64
AF067517-1|AAC72082.1| 565|Homo sapiens PITSLRE protein kinase ... 244 3e-64
AF067516-1|AAC72081.1| 748|Homo sapiens PITSLRE protein kinase ... 244 3e-64
AF067515-1|AAC72080.1| 795|Homo sapiens PITSLRE protein kinase ... 244 3e-64
AF067514-1|AAC72079.1| 737|Homo sapiens PITSLRE protein kinase ... 244 3e-64
AF067513-1|AAC72078.1| 526|Homo sapiens PITSLRE protein kinase ... 244 3e-64
AF067512-1|AAC72077.1| 782|Homo sapiens PITSLRE protein kinase ... 244 3e-64
X78342-1|CAA55137.1| 360|Homo sapiens PISSLRE protein. 241 2e-63
AL353572-4|CAM17657.1| 346|Homo sapiens cell cycle related kina... 241 2e-63
AJ010341-1|CAB37619.1| 360|Homo sapiens cyclin-dependent kinase... 241 2e-63
AF547664-1|AAN28684.1| 346|Homo sapiens cell cycle related kina... 241 2e-63
AF174497-1|AAF36538.1| 565|Homo sapiens GR AF-1 coactivator 3 p... 241 2e-63
L33264-1|AAA60092.2| 314|Homo sapiens CDC2-related protein kina... 239 1e-62
AB020641-1|BAA74857.2| 453|Homo sapiens KIAA0834 protein protein. 238 2e-62
AF119833-1|AAG43234.1| 469|Homo sapiens serine/threonine protei... 237 4e-62
X66363-1|CAA47006.1| 496|Homo sapiens serine/threonine protein ... 236 9e-62
BT006827-1|AAP35473.1| 496|Homo sapiens PCTAIRE protein kinase ... 236 9e-62
BC015607-1|AAH15607.1| 496|Homo sapiens PCTAIRE protein kinase ... 236 9e-62
BC009852-1|AAH09852.2| 395|Homo sapiens PCTK1 protein protein. 236 9e-62
BC006190-1|AAH06190.1| 448|Homo sapiens PCTK1 protein protein. 236 9e-62
BC001048-1|AAH01048.1| 496|Homo sapiens PCTAIRE protein kinase ... 236 9e-62
AL096791-1|CAD20055.1| 496|Homo sapiens PCTAIRE protein kinase ... 236 9e-62
Y00272-1|CAA68376.1| 297|Homo sapiens protein ( Human cell cycl... 235 2e-61
X05360-1|CAA28963.1| 297|Homo sapiens protein ( Human CDC2 gene... 235 2e-61
BT007004-1|AAP35650.1| 297|Homo sapiens cell division cycle 2, ... 235 2e-61
BC014563-1|AAH14563.1| 297|Homo sapiens cell division cycle 2, ... 235 2e-61
AF512554-1|AAM34793.1| 297|Homo sapiens cell division cycle 2, ... 235 2e-61
AY353238-1|AAR13066.1| 504|Homo sapiens PCTAIRE protein kinase ... 233 5e-61
AY353237-1|AAR13065.1| 474|Homo sapiens PCTAIRE protein kinase ... 233 5e-61
AL357131-4|CAH72012.1| 472|Homo sapiens PCTAIRE protein kinase ... 233 5e-61
AB209307-1|BAD92544.1| 436|Homo sapiens PCTAIRE protein kinase ... 233 5e-61
BC033005-1|AAH33005.1| 523|Homo sapiens PCTAIRE protein kinase ... 231 2e-60
BT007299-1|AAP35963.1| 472|Homo sapiens PCTAIRE-motif protein k... 231 3e-60
BC011526-1|AAH11526.1| 472|Homo sapiens PCTAIRE protein kinase ... 231 3e-60
X66362-1|CAA47005.1| 380|Homo sapiens serine/threonine protein ... 230 5e-60
X66360-1|CAA47004.1| 523|Homo sapiens serine/threonine protein ... 230 5e-60
L25676-1|AAA35668.1| 372|Homo sapiens CDC2-related kinase protein. 213 7e-55
BC001968-1|AAH01968.1| 372|Homo sapiens cyclin-dependent kinase... 213 7e-55
AL162586-9|CAI39768.1| 372|Homo sapiens cyclin-dependent kinase... 213 7e-55
AF517840-1|AAM54039.1| 372|Homo sapiens cyclin-dependent kinase... 213 7e-55
BC038807-1|AAH38807.1| 349|Homo sapiens ALS2CR7 protein protein. 212 1e-54
AB053308-1|BAB69017.1| 384|Homo sapiens ALS2CR7 protein. 212 1e-54
X80230-1|CAA56516.1| 372|Homo sapiens serine/threonine protein ... 210 4e-54
AF255306-1|AAF72183.1| 372|Homo sapiens protein kinase CDK9 pro... 210 4e-54
BT019903-1|AAV38706.1| 372|Homo sapiens cyclin-dependent kinase... 210 5e-54
BC107750-1|AAI07751.1| 225|Homo sapiens CDC2 protein protein. 208 3e-53
AC007242-1|AAX93182.1| 301|Homo sapiens unknown protein. 205 2e-52
BC025301-1|AAH25301.1| 272|Homo sapiens CDK10 protein protein. 205 2e-52
BC017342-1|AAH17342.1| 283|Homo sapiens CDK10 protein protein. 199 1e-50
AY847283-1|AAW31760.1| 379|Homo sapiens cyclin-dependent kinase... 193 9e-49
AY845084-1|AAW30008.1| 315|Homo sapiens cyclin-dependent kinase... 193 9e-49
AY679523-1|AAT74623.1| 1512|Homo sapiens cell division cycle 2-l... 193 9e-49
AJ297710-1|CAC10401.1| 1452|Homo sapiens CDC2L5 protein kinase p... 193 9e-49
AJ297709-1|CAC10400.1| 1512|Homo sapiens CDC2L5 protein kinase p... 193 9e-49
X66358-1|CAA47002.1| 358|Homo sapiens serine/threonine protein ... 191 3e-48
BC104977-1|AAI04978.1| 358|Homo sapiens cyclin-dependent kinase... 191 3e-48
AY525548-1|AAS00095.1| 358|Homo sapiens cyclin-dependent kinase... 191 3e-48
AB020711-1|BAA74927.2| 1535|Homo sapiens KIAA0904 protein protein. 190 5e-48
BC000281-1|AAH00281.2| 283|Homo sapiens PCTK3 protein protein. 190 8e-48
AF227198-1|AAF36401.1| 1490|Homo sapiens CrkRS protein. 189 1e-47
M80629-1|AAA58424.1| 418|Homo sapiens cdc2-related protein kina... 187 4e-47
U35146-1|AAC50918.1| 493|Homo sapiens p56 KKIAMRE protein kinas... 187 6e-47
BC093981-1|AAH93981.1| 493|Homo sapiens cyclin-dependent kinase... 187 6e-47
BC093646-1|AAH93646.1| 493|Homo sapiens cyclin-dependent kinase... 187 6e-47
BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein. 183 9e-46
AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protei... 183 9e-46
Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-l... 182 2e-45
Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein. 182 2e-45
AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase... 182 2e-45
AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent kinase... 182 2e-45
AL162581-2|CAI19518.1| 632|Homo sapiens RP1-132F22.1 protein. 181 4e-45
AL031178-1|CAI20261.1| 632|Homo sapiens RP1-132F22.1 protein. 181 4e-45
AF152469-1|AAG43364.1| 632|Homo sapiens MAK-related kinase prot... 181 4e-45
AB023153-1|BAA76780.2| 640|Homo sapiens KIAA0936 protein protein. 181 4e-45
U81031-1|AAC39521.2| 303|Homo sapiens CDK4 protein. 180 6e-45
U37022-1|AAC50506.1| 303|Homo sapiens cyclin-dependent kinase 4... 180 6e-45
M14505-1|AAA35673.1| 303|Homo sapiens cyclin-dependent protein ... 180 6e-45
CR542247-1|CAG47043.1| 303|Homo sapiens CDK4 protein. 180 6e-45
CR407668-1|CAG28596.1| 303|Homo sapiens CDK4 protein. 180 6e-45
BC010153-1|AAH10153.1| 303|Homo sapiens cyclin-dependent kinase... 180 6e-45
BC005864-1|AAH05864.1| 303|Homo sapiens cyclin-dependent kinase... 180 6e-45
BC003644-1|AAH03644.1| 303|Homo sapiens cyclin-dependent kinase... 180 6e-45
AF507942-1|AAM23014.1| 303|Homo sapiens cyclin-dependent kinase... 180 6e-45
AL353572-3|CAH72843.1| 325|Homo sapiens cell cycle related kina... 179 1e-44
AF113130-1|AAF43778.1| 452|Homo sapiens cyclin-dependent protei... 179 1e-44
AF035013-1|AAC98920.1| 452|Homo sapiens cell cycle related kina... 179 1e-44
Z48970-1|CAA88834.1| 303|Homo sapiens orf protein. 178 3e-44
AF225919-1|AAF37278.1| 632|Homo sapiens intestinal cell kinase ... 178 3e-44
Z11695-1|CAA77753.1| 348|Homo sapiens 40kDa protein kinase prot... 177 3e-44
Z11694-1|CAA77752.1| 360|Homo sapiens 41kD protein kinase protein. 177 3e-44
M84489-1|AAA58459.1| 360|Homo sapiens protein kinase 2 protein. 177 3e-44
DQ508104-1|ABF47102.1| 360|Homo sapiens mitogen-activated prote... 177 3e-44
BC017832-1|AAH17832.1| 360|Homo sapiens mitogen-activated prote... 177 3e-44
BC039825-1|AAH39825.1| 457|Homo sapiens MAK protein protein. 177 5e-44
AL024498-4|CAB75823.1| 623|Homo sapiens protein ( Human DNA seq... 177 5e-44
AF505623-1|AAN16405.1| 623|Homo sapiens male germ cell-associat... 177 5e-44
AY065978-1|AAL40897.1| 544|Homo sapiens extracellular signal-re... 176 1e-43
AK131512-1|BAD18656.1| 345|Homo sapiens protein ( Homo sapiens ... 176 1e-43
BC099905-1|AAH99905.1| 360|Homo sapiens mitogen-activated prote... 175 2e-43
Z84480-1|CAI20520.1| 502|Homo sapiens cell division cycle 2-lik... 174 3e-43
X66365-1|CAA47008.1| 326|Homo sapiens serine/threonine protein ... 174 3e-43
BC052264-1|AAH52264.1| 326|Homo sapiens cyclin-dependent kinase... 174 3e-43
BC037289-1|AAH37289.1| 502|Homo sapiens CDC2L6 protein protein. 174 3e-43
AY128534-1|AAM76970.1| 326|Homo sapiens cyclin-dependent kinase... 174 3e-43
AY028424-1|AAK27731.1| 502|Homo sapiens death-preventing kinase... 174 3e-43
AL603914-4|CAI41175.1| 502|Homo sapiens cell division cycle 2-l... 174 3e-43
AL512430-4|CAI40286.1| 502|Homo sapiens cell division cycle 2-l... 174 3e-43
AB028951-1|BAA82980.2| 501|Homo sapiens KIAA1028 protein protein. 174 3e-43
DQ411039-1|ABD66016.1| 260|Homo sapiens protein kinase CDK5 spl... 173 6e-43
U29727-1|AAA82933.1| 816|Homo sapiens BMK1 gamma kinase protein. 173 1e-42
U29726-1|AAA82932.1| 816|Homo sapiens BMK1 beta kinase protein. 173 1e-42
U29725-1|AAA82931.1| 816|Homo sapiens BMK1 alpha kinase protein. 173 1e-42
U25278-1|AAA81381.1| 815|Homo sapiens ERK5 protein. 173 1e-42
BC035807-1|AAH35807.1| 292|Homo sapiens ICK protein protein. 173 1e-42
BC030134-1|AAH30134.1| 816|Homo sapiens mitogen-activated prote... 173 1e-42
BC009963-1|AAH09963.1| 816|Homo sapiens mitogen-activated prote... 173 1e-42
AY534741-1|AAS38577.1| 533|Homo sapiens mitogen activated prote... 173 1e-42
L35264-1|AAA57456.1| 360|Homo sapiens CSaids binding protein pr... 172 2e-42
L35253-1|AAA74301.1| 360|Homo sapiens MAP kinase protein. 172 2e-42
CR536505-1|CAG38743.1| 360|Homo sapiens MAPK14 protein. 172 2e-42
BT006933-1|AAP35579.1| 360|Homo sapiens mitogen-activated prote... 172 2e-42
BC031574-1|AAH31574.1| 360|Homo sapiens mitogen-activated prote... 172 2e-42
BC000092-1|AAH00092.1| 360|Homo sapiens mitogen-activated prote... 172 2e-42
AF100544-1|AAF36770.1| 360|Homo sapiens stress-activated protei... 172 2e-42
Y14440-1|CAA74792.1| 364|Homo sapiens stress activated protein ... 171 3e-42
X85753-1|CAA59754.1| 464|Homo sapiens CDK8 protein kinase protein. 171 3e-42
U92268-1|AAB66313.1| 364|Homo sapiens mitogen activated protein... 171 3e-42
DQ279722-1|ABB72677.1| 364|Homo sapiens mitogen-activated prote... 171 3e-42
CR456514-1|CAG30400.1| 364|Homo sapiens MAPK11 protein. 171 3e-42
BC107601-1|AAI07602.1| 463|Homo sapiens cyclin-dependent kinase... 171 3e-42
BC105950-1|AAI05951.1| 463|Homo sapiens cyclin-dependent kinase... 171 3e-42
BC104492-1|AAI04493.1| 464|Homo sapiens cyclin-dependent kinase... 171 3e-42
BC069634-1|AAH69634.1| 463|Homo sapiens cyclin-dependent kinase... 171 3e-42
BC027933-1|AAH27933.1| 364|Homo sapiens mitogen-activated prote... 171 3e-42
AL590108-1|CAH72300.1| 464|Homo sapiens cyclin-dependent kinase... 171 3e-42
AL159159-1|CAI16960.1| 464|Homo sapiens cyclin-dependent kinase... 171 3e-42
AL022328-13|CAB51539.1| 364|Homo sapiens mitogen-activated prot... 171 3e-42
AF031135-1|AAC12714.1| 364|Homo sapiens p38beta2 MAP kinase pro... 171 3e-42
AF001174-1|AAC51373.1| 364|Homo sapiens p38beta2 MAP kinase pro... 171 3e-42
AF001008-1|AAC51250.1| 364|Homo sapiens p38Beta2 MAP Kinase pro... 171 3e-42
Z11696-1|CAA77754.1| 355|Homo sapiens 44kDa protein kinase prot... 169 9e-42
M84490-1|AAA36142.1| 366|Homo sapiens kinase 1 protein. 169 9e-42
BC013992-1|AAH13992.1| 379|Homo sapiens mitogen-activated prote... 169 9e-42
L35263-1|AAA57455.1| 360|Homo sapiens CSaids binding protein pr... 169 2e-41
X60188-1|CAA42744.1| 379|Homo sapiens protein serine/threonine ... 167 5e-41
Z95152-3|CAB08438.1| 365|Homo sapiens mitogen-activated protein... 167 6e-41
Y10488-1|CAA71512.1| 365|Homo sapiens stress-activated protein ... 167 6e-41
U93232-1|AAB87639.1| 365|Homo sapiens MAP kinase p38delta protein. 167 6e-41
CR541687-1|CAG46488.1| 365|Homo sapiens MAPK13 protein. 167 6e-41
CR536490-1|CAG38729.1| 365|Homo sapiens MAPK13 protein. 167 6e-41
BT007221-1|AAP35885.1| 365|Homo sapiens mitogen-activated prote... 167 6e-41
BC004428-1|AAH04428.1| 365|Homo sapiens mitogen-activated prote... 167 6e-41
BC001641-1|AAH01641.1| 365|Homo sapiens mitogen-activated prote... 167 6e-41
BC000433-1|AAH00433.1| 365|Homo sapiens mitogen-activated prote... 167 6e-41
AF100546-1|AAF36772.1| 365|Homo sapiens stress-activated protei... 167 6e-41
AY033607-1|AAK52329.1| 357|Homo sapiens extracellular signal-re... 166 9e-41
AF092535-1|AAD23377.1| 365|Homo sapiens mitogen-activated prote... 166 9e-41
U53442-1|AAB05036.1| 372|Homo sapiens p38Beta MAP kinase protein. 165 1e-40
AL353572-5|CAM17658.1| 338|Homo sapiens cell cycle related kina... 165 2e-40
BC002655-1|AAH02655.1| 275|Homo sapiens CCRK protein protein. 165 3e-40
AF015256-1|AAC51758.1| 365|Homo sapiens p38 mitogen-activated p... 164 3e-40
AY994058-1|AAY44299.1| 254|Homo sapiens extracellular regulated... 164 5e-40
AF004709-1|AAC51374.1| 365|Homo sapiens stress-activated protei... 164 5e-40
L40027-1|AAA62432.1| 483|Homo sapiens glycogen synthase kinase ... 163 6e-40
D63424-1|BAA23608.1| 483|Homo sapiens glycogen synthase kinase ... 163 6e-40
BC051865-1|AAH51865.1| 483|Homo sapiens glycogen synthase kinas... 163 6e-40
BC027984-1|AAH27984.1| 483|Homo sapiens glycogen synthase kinas... 163 6e-40
BC001274-1|AAH01274.1| 324|Homo sapiens CDC2L5 protein protein. 163 6e-40
AC006486-1|AAD11986.1| 483|Homo sapiens KG3A_HUMAN protein. 163 6e-40
BC024247-1|AAH24247.1| 502|Homo sapiens CDC2L6 protein protein. 163 1e-39
U66243-1|AAB40118.1| 367|Homo sapiens p38gamma MAP Kinase protein. 162 2e-39
Y10487-1|CAA71511.1| 367|Homo sapiens stress-activated protein ... 161 2e-39
BC015741-1|AAH15741.1| 367|Homo sapiens mitogen-activated prote... 161 2e-39
AL022328-12|CAB51538.1| 367|Homo sapiens mitogen-activated prot... 161 2e-39
AL603914-2|CAI41172.1| 442|Homo sapiens cell division cycle 2-l... 159 2e-38
AL512430-1|CAI40282.1| 442|Homo sapiens cell division cycle 2-l... 159 2e-38
AC006036-1|AAF19245.1| 165|Homo sapiens unknown protein. 157 7e-38
X79483-1|CAA55984.1| 367|Homo sapiens extracellular signal regu... 156 9e-38
CR536510-1|CAG38748.1| 420|Homo sapiens GSK3B protein. 155 2e-37
BC012760-1|AAH12760.1| 420|Homo sapiens GSK3B protein protein. 155 2e-37
BX537897-1|CAD97888.1| 323|Homo sapiens hypothetical protein pr... 155 3e-37
L33801-1|AAA66475.1| 420|Homo sapiens protein kinase protein. 154 5e-37
U19775-1|AAC50329.1| 297|Homo sapiens Mxi2 protein. 153 6e-37
AB074150-1|BAB85654.1| 307|Homo sapiens Alternative spliced var... 153 6e-37
AB022694-1|BAA81688.1| 419|Homo sapiens MOK protein kinase prot... 153 6e-37
AY033608-1|AAK52330.1| 335|Homo sapiens extracellular signal-re... 153 1e-36
X59727-1|CAA42411.1| 557|Homo sapiens 63kDa protein kinase prot... 151 3e-36
BC117216-1|AAI17217.1| 587|Homo sapiens mitogen-activated prote... 151 3e-36
BC050299-1|AAH50299.1| 587|Homo sapiens mitogen-activated prote... 151 5e-36
AC006023-1|AAD54514.1| 727|Homo sapiens WUGSC:H_DJ1147A01.1 pro... 151 5e-36
BC000251-1|AAH00251.1| 433|Homo sapiens glycogen synthase kinas... 150 6e-36
BC040529-1|AAH40529.1| 231|Homo sapiens PCTK3 protein protein. 149 1e-35
BC035492-1|AAH35492.1| 721|Homo sapiens mitogen-activated prote... 148 2e-35
AB012305-1|BAA32794.1| 264|Homo sapiens d-HSCDK2 protein. 148 2e-35
X80692-1|CAA56709.1| 721|Homo sapiens p97mapk protein. 148 3e-35
L77964-1|AAA98769.1| 721|Homo sapiens ERK3 protein kinase protein. 148 3e-35
AF420474-1|AAL17605.1| 721|Homo sapiens ERK-3 protein. 148 3e-35
BC028034-1|AAH28034.1| 277|Homo sapiens MAPK15 protein protein. 147 4e-35
AL603914-3|CAI41173.1| 251|Homo sapiens cell division cycle 2-l... 147 6e-35
AL512430-2|CAI40283.1| 251|Homo sapiens cell division cycle 2-l... 147 6e-35
DQ316259-1|ABC40748.1| 516|Homo sapiens nemo like kinase protein. 146 7e-35
BC064663-1|AAH64663.1| 515|Homo sapiens nemo-like kinase protein. 146 7e-35
AF197898-1|AAF04857.1| 515|Homo sapiens nemo-like kinase protein. 146 7e-35
AF180819-1|AAD56013.1| 515|Homo sapiens LAK1 protein protein. 146 7e-35
BC053536-1|AAH53536.1| 231|Homo sapiens RAGE protein protein. 144 3e-34
Z95152-2|CAI19690.1| 355|Homo sapiens mitogen-activated protein... 143 7e-34
Y13493-1|CAA73885.1| 528|Homo sapiens protein kinase Dyrk2 prot... 142 2e-33
BC006375-1|AAH06375.1| 601|Homo sapiens DYRK2 protein protein. 142 2e-33
BC005809-1|AAH05809.1| 528|Homo sapiens dual-specificity tyrosi... 142 2e-33
U79269-1|AAB50213.1| 229|Homo sapiens cyclin dependent protein ... 141 3e-33
CR456515-1|CAG30401.1| 357|Homo sapiens MAPK12 protein. 139 1e-32
AB209611-1|BAD92848.1| 453|Homo sapiens Mitogen activated prote... 138 3e-32
U34820-1|AAC50605.1| 422|Homo sapiens JNK3 alpha1 protein kinas... 137 6e-32
U34819-1|AAC50604.1| 464|Homo sapiens JNK3 alpha2 protein kinas... 137 6e-32
U07620-1|AAC50101.1| 422|Homo sapiens MAP kinase protein. 137 6e-32
BC035057-1|AAH35057.1| 464|Homo sapiens MAPK10 protein protein. 137 6e-32
U34822-1|AAC50607.1| 427|Homo sapiens JNK1 alpha2 protein kinas... 136 1e-31
L26318-1|AAA36131.1| 384|Homo sapiens protein kinase protein. 136 1e-31
AK222922-1|BAD96642.1| 307|Homo sapiens MAPK13 protein (Fragmen... 135 2e-31
U35005-1|AAC50611.1| 427|Homo sapiens JNK1 beta2 protein kinase... 135 2e-31
U35004-1|AAC50610.1| 384|Homo sapiens JNK1 beta1 protein kinase... 135 2e-31
BC130572-1|AAI30573.1| 427|Homo sapiens mitogen-activated prote... 135 2e-31
BC130570-1|AAI30571.1| 427|Homo sapiens mitogen-activated prote... 135 2e-31
U35003-1|AAC50609.1| 424|Homo sapiens JNK2 beta2 protein kinase... 134 6e-31
U35002-1|AAC50608.1| 382|Homo sapiens JNK2 beta1 protein kinase... 134 6e-31
BC007992-1|AAH07992.1| 677|Homo sapiens mitogen-activated prote... 133 7e-31
BC007404-1|AAH07404.1| 677|Homo sapiens mitogen-activated prote... 133 7e-31
BX640648-1|CAE45794.1| 319|Homo sapiens hypothetical protein pr... 131 4e-30
AY590695-1|AAT06103.1| 588|Homo sapiens dual-specificity tyrosi... 131 4e-30
AL591846-9|CAI13541.1| 568|Homo sapiens dual-specificity tyrosi... 131 4e-30
AL591846-7|CAI13539.1| 588|Homo sapiens dual-specificity tyrosi... 131 4e-30
AF327561-1|AAK16443.1| 568|Homo sapiens dual-specificity tyrosi... 131 4e-30
AF186774-1|AAG17029.1| 568|Homo sapiens regulatory erythroid ki... 131 4e-30
AF186773-1|AAG17028.1| 588|Homo sapiens regulatory erythroid ki... 131 4e-30
BC015501-1|AAH15501.1| 568|Homo sapiens dual-specificity tyrosi... 130 9e-30
Y12735-1|CAA73266.2| 588|Homo sapiens Dyrk3 protein protein. 128 4e-29
U34821-1|AAC50606.1| 382|Homo sapiens JNK2 alpha1 protein kinas... 127 5e-29
L31951-1|AAA56831.1| 424|Homo sapiens protein kinase protein. 127 5e-29
U09759-1|AAA74740.1| 424|Homo sapiens protein kinase protein. 127 6e-29
DQ066599-1|AAY46156.1| 424|Homo sapiens mitogen-activated prote... 127 6e-29
CR536580-1|CAG38817.1| 424|Homo sapiens MAPK9 protein. 127 6e-29
BC032539-1|AAH32539.1| 424|Homo sapiens mitogen-activated prote... 127 6e-29
AY904367-1|AAW82349.1| 243|Homo sapiens cell cycle-related kina... 126 1e-28
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 122 1e-27
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 122 1e-27
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 122 1e-27
AL357131-3|CAH72011.1| 280|Homo sapiens PCTAIRE protein kinase ... 122 2e-27
BC031244-1|AAH31244.1| 520|Homo sapiens dual-specificity tyrosi... 118 3e-26
AF263541-1|AAF91393.1| 541|Homo sapiens protein kinase DYRK4 pr... 118 3e-26
M55268-1|AAA51548.1| 350|Homo sapiens casein kinase II alpha' s... 118 4e-26
BC008812-1|AAH08812.1| 350|Homo sapiens casein kinase 2, alpha ... 118 4e-26
CR542222-1|CAG47018.1| 306|Homo sapiens NEK6 protein. 116 2e-25
BC012761-1|AAH12761.1| 313|Homo sapiens NIMA (never in mitosis ... 116 2e-25
BC004209-1|AAH04209.2| 313|Homo sapiens NEK6 protein protein. 116 2e-25
BC004174-1|AAH04174.2| 313|Homo sapiens NEK6 protein protein. 116 2e-25
BC000101-1|AAH00101.2| 313|Homo sapiens NEK6 protein protein. 116 2e-25
AL162724-9|CAH70254.1| 313|Homo sapiens NIMA (never in mitosis ... 116 2e-25
AL162724-2|CAH70247.1| 347|Homo sapiens NIMA (never in mitosis ... 116 2e-25
AL137846-13|CAI10883.1| 313|Homo sapiens NIMA (never in mitosis... 116 2e-25
AL137846-6|CAI10876.1| 347|Homo sapiens NIMA (never in mitosis ... 116 2e-25
AF087909-1|AAG13417.1| 338|Homo sapiens NIMA-related kinase 6 p... 116 2e-25
AB026289-1|BAA85045.1| 306|Homo sapiens protein kinase SID6-151... 116 2e-25
CR457091-1|CAG33372.1| 306|Homo sapiens NEK6 protein. 114 5e-25
S53149-1|ABB72474.1| 391|Homo sapiens casein kinase II-alpha su... 112 1e-24
M55265-1|AAA35503.1| 391|Homo sapiens casein kinase II alpha su... 112 1e-24
J02853-1|AAA56821.1| 391|Homo sapiens casein kinase II alpha su... 112 1e-24
DQ354583-1|ABC86794.1| 385|Homo sapiens casein kinase 2 alpha i... 112 1e-24
BT019792-1|AAV38595.1| 391|Homo sapiens casein kinase 2, alpha ... 112 1e-24
BC071167-1|AAH71167.1| 391|Homo sapiens casein kinase 2, alpha ... 112 1e-24
BC053532-1|AAH53532.1| 391|Homo sapiens casein kinase 2, alpha ... 112 1e-24
BC050036-1|AAH50036.1| 397|Homo sapiens CSNK2A1 protein protein. 112 1e-24
BC011668-1|AAH11668.1| 391|Homo sapiens casein kinase 2, alpha ... 112 1e-24
AL049761-3|CAB65624.1| 391|Homo sapiens casein kinase 2, alpha ... 112 1e-24
AF390028-1|AAL58838.1| 993|Homo sapiens serine/threonine protei... 112 1e-24
X70251-1|CAA49758.1| 391|Homo sapiens casein kinase II alpha su... 111 4e-24
AY112721-1|AAM52224.1| 391|Homo sapiens casein kinase II alpha ... 111 4e-24
BC085196-1|AAH85196.1| 257|Homo sapiens MAPK13 protein protein. 110 6e-24
AL122015-2|CAJ55828.1| 1194|Homo sapiens homeodomain interacting... 110 8e-24
AL122015-1|CAC13164.1| 1215|Homo sapiens homeodomain interacting... 110 8e-24
AF305239-1|AAG25990.1| 1194|Homo sapiens Fas-interacting serine/... 110 8e-24
AF004849-1|AAC64294.1| 1215|Homo sapiens PKY protein kinase prot... 110 8e-24
AF326592-1|AAL37371.1| 1171|Homo sapiens homeodomain interacting... 109 2e-23
AF208291-1|AAG41236.1| 1198|Homo sapiens protein kinase HIPK2 pr... 109 2e-23
AF042838-1|AAC97073.1| 1495|Homo sapiens MEK kinase 1 protein. 108 2e-23
BC033012-1|AAH33012.1| 1075|Homo sapiens homeodomain interacting... 107 4e-23
AL731797-3|CAI22793.1| 1210|Homo sapiens homeodomain interacting... 107 4e-23
AL731797-2|CAI22794.1| 1165|Homo sapiens homeodomain interacting... 107 4e-23
AL731797-1|CAI22792.1| 1075|Homo sapiens homeodomain interacting... 107 4e-23
AB089957-1|BAC57075.1| 1210|Homo sapiens homeodomain-interacting... 107 4e-23
AF207702-1|AAG35710.1| 911|Homo sapiens homeodomain-interacting... 107 6e-23
AF067525-1|AAC72090.1| 528|Homo sapiens PITSLRE protein kinase ... 107 6e-23
BC051731-1|AAH51731.1| 319|Homo sapiens MAPK10 protein protein. 107 7e-23
AB062450-1|BAB85632.1| 302|Homo sapiens NEK7 protein. 107 7e-23
BC034501-1|AAH34501.1| 616|Homo sapiens homeodomain interacting... 105 2e-22
AK057380-1|BAB71458.1| 541|Homo sapiens protein ( Homo sapiens ... 105 2e-22
BC109097-1|AAI09098.2| 795|Homo sapiens MLCK protein protein. 105 3e-22
AJ247087-1|CAC42766.1| 795|Homo sapiens myosin light chain kina... 105 3e-22
AB209465-1|BAD92702.1| 556|Homo sapiens Hypothetical protein FL... 105 3e-22
BC065516-1|AAH65516.1| 319|Homo sapiens MAPK10 protein protein. 104 5e-22
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 103 7e-22
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 103 7e-22
AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3 (Dro... 103 7e-22
AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3 (Dr... 103 7e-22
AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 vari... 103 7e-22
AB209586-1|BAD92823.1| 255|Homo sapiens mitogen-activated prote... 103 9e-22
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 102 2e-21
BC132833-1|AAI32834.1| 388|Homo sapiens hypothetical protein LO... 101 4e-21
BC132831-1|AAI32832.1| 388|Homo sapiens hypothetical protein LO... 101 4e-21
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 101 4e-21
AL139092-1|CAH73662.1| 388|Homo sapiens protein ( Human DNA seq... 101 4e-21
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 101 4e-21
AL138876-2|CAI12221.2| 388|Homo sapiens protein ( Human DNA seq... 101 4e-21
AL162724-7|CAH70252.1| 222|Homo sapiens NIMA (never in mitosis ... 100 6e-21
AL162724-6|CAH70251.1| 220|Homo sapiens NIMA (never in mitosis ... 100 6e-21
AL162724-5|CAH70250.1| 219|Homo sapiens NIMA (never in mitosis ... 100 6e-21
AL137846-11|CAI10881.1| 222|Homo sapiens NIMA (never in mitosis... 100 6e-21
AL137846-10|CAI10880.1| 220|Homo sapiens NIMA (never in mitosis... 100 6e-21
AL137846-9|CAI10879.1| 219|Homo sapiens NIMA (never in mitosis ... 100 6e-21
Y17999-3|CAA76990.1| 589|Homo sapiens Dyrk1B protein kinase pro... 99 1e-20
Y17999-2|CAA76989.1| 601|Homo sapiens Dyrk1B protein kinase pro... 99 1e-20
Y17999-1|CAA76991.1| 629|Homo sapiens Dyrk1B protein kinase pro... 99 1e-20
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 99 1e-20
D88357-1|BAA26001.1| 240|Homo sapiens CDC2 delta T protein. 99 1e-20
BC133039-1|AAI33040.1| 1001|Homo sapiens TAO kinase 1 protein. 99 1e-20
BC025291-1|AAH25291.1| 629|Homo sapiens dual-specificity tyrosi... 99 1e-20
BC018751-1|AAH18751.1| 629|Homo sapiens dual-specificity tyrosi... 99 1e-20
AY049015-1|AAL12217.1| 1001|Homo sapiens serine/threonine kinase... 99 1e-20
AF263312-1|AAG38502.1| 1001|Homo sapiens STE20-like kinase protein. 99 1e-20
AF205861-1|AAF15893.1| 629|Homo sapiens protein kinase MIRK pro... 99 1e-20
AB037782-1|BAA92599.1| 1005|Homo sapiens KIAA1361 protein protein. 99 1e-20
DQ234352-1|ABB29981.1| 308|Homo sapiens mitogen-activated prote... 100 1e-20
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 99 2e-20
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 99 2e-20
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 99 2e-20
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 99 2e-20
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 99 2e-20
U71087-1|AAB16851.1| 448|Homo sapiens MAP kinase kinase MEK5b p... 99 3e-20
CR542229-1|CAG47025.1| 448|Homo sapiens MAP2K5 protein. 99 3e-20
BT006780-1|AAP35426.1| 448|Homo sapiens mitogen-activated prote... 99 3e-20
BC008838-1|AAH08838.1| 448|Homo sapiens mitogen-activated prote... 99 3e-20
U48736-1|AAB03268.1| 496|Homo sapiens serine/threonine-protein ... 98 3e-20
BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9 p... 98 3e-20
BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis ... 98 3e-20
BC051798-1|AAH51798.1| 1426|Homo sapiens TAOK2 protein protein. 98 3e-20
BC031825-1|AAH31825.1| 560|Homo sapiens TAOK2 protein protein. 98 3e-20
BC015204-1|AAH15204.1| 762|Homo sapiens Unknown (protein for IM... 98 3e-20
BC009844-1|AAH09844.1| 496|Homo sapiens PRPF4B protein protein. 98 3e-20
AY574904-1|AAT81413.1| 510|Homo sapiens regulated in COPD kinas... 98 3e-20
AY574902-1|AAT81411.1| 1215|Homo sapiens regulated in COPD kinas... 98 3e-20
AY574901-1|AAT81410.1| 1328|Homo sapiens regulated in COPD kinas... 98 3e-20
AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERC... 98 3e-20
AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek... 98 3e-20
AY029347-1|AAK38155.1| 1007|Homo sapiens serine/threonine-protei... 98 3e-20
AL138831-3|CAI20480.1| 1007|Homo sapiens PRP4 pre-mRNA processin... 98 3e-20
AL033383-1|CAI42121.1| 1007|Homo sapiens PRP4 pre-mRNA processin... 98 3e-20
AF283465-1|AAM19101.1| 1007|Homo sapiens PRP4 kinase protein. 98 3e-20
AF263313-1|AAG38503.1| 1049|Homo sapiens STE20-like kinase protein. 98 3e-20
AF061943-1|AAD45616.1| 1235|Homo sapiens prostate derived STE20-... 98 3e-20
AC007055-5|AAD31940.1| 312|Homo sapiens protein ( Homo sapiens ... 98 3e-20
AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein. 98 3e-20
AB020688-1|BAA74904.2| 1064|Homo sapiens KIAA0881 protein protein. 98 3e-20
AB011108-1|BAA25462.1| 1028|Homo sapiens KIAA0536 protein protein. 98 3e-20
BC034969-1|AAH34969.1| 1007|Homo sapiens PRP4 pre-mRNA processin... 98 4e-20
AK223053-1|BAD96773.1| 597|Homo sapiens cell division cycle 2-l... 97 6e-20
BC117311-1|AAI17312.1| 898|Homo sapiens CASK protein protein. 97 1e-19
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 97 1e-19
AY705392-1|AAU10527.1| 921|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL627402-6|CAH71241.1| 590|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL627402-5|CAH71238.1| 897|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL627402-4|CAH71237.1| 909|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL627402-3|CAH71240.1| 926|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL627402-2|CAH71239.1| 921|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL603754-6|CAI41638.1| 590|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL603754-5|CAI41635.1| 926|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL603754-4|CAI41636.1| 921|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL603754-3|CAI41637.1| 897|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL603754-2|CAI41634.1| 909|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL445239-7|CAI41096.1| 590|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL445239-6|CAI41093.1| 926|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL445239-5|CAI41094.1| 921|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL445239-4|CAI41095.1| 897|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL445239-3|CAI41092.1| 909|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL353691-7|CAI42248.1| 590|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL353691-6|CAI42245.1| 926|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL353691-5|CAI42246.1| 921|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL353691-4|CAI42247.1| 897|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL353691-3|CAI42244.1| 909|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL158144-5|CAI42766.1| 590|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL158144-4|CAI42763.1| 926|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL158144-3|CAI42764.1| 921|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL158144-2|CAI42765.1| 897|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AL158144-1|CAI42762.1| 909|Homo sapiens calcium/calmodulin-depe... 97 1e-19
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 97 1e-19
AF035582-1|AAB88198.1| 897|Homo sapiens CASK protein. 97 1e-19
AF032119-1|AAB88125.1| 921|Homo sapiens hCASK protein. 97 1e-19
AB208859-1|BAD92096.1| 917|Homo sapiens calcium/calmodulin-depe... 97 1e-19
U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein. 96 1e-19
D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein. 96 1e-19
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 96 1e-19
BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein. 96 1e-19
BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein. 96 1e-19
BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein. 96 1e-19
BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein. 96 1e-19
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 96 1e-19
AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related serine\/t... 96 1e-19
AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related serine\/t... 96 1e-19
AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related serine\/t... 96 1e-19
AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related serine\/t... 96 1e-19
AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20... 96 1e-19
AF181985-1|AAF25817.1| 898|Homo sapiens serine/threonine kinase... 96 1e-19
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 96 1e-19
AB209829-1|BAD93066.1| 214|Homo sapiens cyclin-dependent kinase... 96 1e-19
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 96 1e-19
AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein. 96 1e-19
BT007185-1|AAP35849.1| 898|Homo sapiens STE20-like kinase protein. 96 2e-19
BC002756-1|AAH02756.1| 898|Homo sapiens TAO kinase 3 protein. 96 2e-19
AL732423-2|CAM17479.1| 748|Homo sapiens mitogen-activated prote... 96 2e-19
AL732423-1|CAM17478.1| 788|Homo sapiens mitogen-activated prote... 96 2e-19
AL732326-2|CAM23143.1| 788|Homo sapiens mitogen-activated prote... 96 2e-19
AL732326-1|CAM23142.1| 748|Homo sapiens mitogen-activated prote... 96 2e-19
AK131412-1|BAD18559.1| 748|Homo sapiens protein ( Homo sapiens ... 96 2e-19
AF179867-1|AAF14559.1| 898|Homo sapiens STE20-like kinase protein. 96 2e-19
AF135158-1|AAG09131.1| 898|Homo sapiens serine kinase protein. 96 2e-19
U71088-1|AAB16852.2| 444|Homo sapiens MAP kinase kinase MEK5c p... 95 2e-19
U25265-1|AAA96146.1| 438|Homo sapiens MEK5 protein. 95 2e-19
L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine ... 94 6e-19
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 94 6e-19
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 94 6e-19
BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein. 94 6e-19
BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for IM... 94 6e-19
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 94 6e-19
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 94 6e-19
AL162724-4|CAH70249.1| 207|Homo sapiens NIMA (never in mitosis ... 94 6e-19
AL137846-8|CAI10878.1| 207|Homo sapiens NIMA (never in mitosis ... 94 6e-19
AF263311-1|AAG38501.1| 898|Homo sapiens STE20-like kinase protein. 94 6e-19
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 94 6e-19
U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kin... 94 7e-19
BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activate... 94 7e-19
AF071884-1|AAC24716.1| 553|Homo sapiens p21 activated kinase 1B... 94 7e-19
AK131477-1|BAD18622.1| 788|Homo sapiens protein ( Homo sapiens ... 93 1e-18
Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4... 93 1e-18
Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4... 93 1e-18
U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein ... 93 1e-18
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 93 1e-18
>X79193-1|CAA55785.1| 346|Homo sapiens MO15/CDK-activating kinase
(CAK) protein.
Length = 346
Score = 482 bits (1189), Expect = e-136
Identities = 229/336 (68%), Positives = 273/336 (81%), Gaps = 4/336 (1%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RYEK+DFLGEGQFATVYKA+D T++IVA+KKIK+G R EA+DGINRTALREIKLLQEL
Sbjct: 11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N+IGLLD FG KSN+SLVFDFM+TDLE+IIKDN++VLTP+++KAYM+MTL+GLEYLHQ
Sbjct: 71 HPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQ 130
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+WILHRDLKPN LL++ G+LK+ DFGLAK+FGSP R THQVVTRWYRAPELLFGAR Y
Sbjct: 131 HWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMY 190
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFK 246
G GVDMWAVGCILAELLLRVPFLPG+SDLDQL+RIF+ GTPTEE WP M +L DYV FK
Sbjct: 191 GVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFK 250
Query: 247 LFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLPMP 306
FP L HIFSAA +DL+ L++ L P R TQAL+M YFS++P P+ G +LP P
Sbjct: 251 SFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRP 310
Query: 307 S-NISKL-EVEKPSL--KRKLLDNIDGGSLAKRLQF 338
+ + L E P+L KRK + ++ G L K+L F
Sbjct: 311 NCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF 346
>X77743-1|CAA54793.1| 346|Homo sapiens CDK activating kinase
protein.
Length = 346
Score = 482 bits (1189), Expect = e-136
Identities = 229/336 (68%), Positives = 273/336 (81%), Gaps = 4/336 (1%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RYEK+DFLGEGQFATVYKA+D T++IVA+KKIK+G R EA+DGINRTALREIKLLQEL
Sbjct: 11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N+IGLLD FG KSN+SLVFDFM+TDLE+IIKDN++VLTP+++KAYM+MTL+GLEYLHQ
Sbjct: 71 HPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQ 130
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+WILHRDLKPN LL++ G+LK+ DFGLAK+FGSP R THQVVTRWYRAPELLFGAR Y
Sbjct: 131 HWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMY 190
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFK 246
G GVDMWAVGCILAELLLRVPFLPG+SDLDQL+RIF+ GTPTEE WP M +L DYV FK
Sbjct: 191 GVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFK 250
Query: 247 LFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLPMP 306
FP L HIFSAA +DL+ L++ L P R TQAL+M YFS++P P+ G +LP P
Sbjct: 251 SFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRP 310
Query: 307 S-NISKL-EVEKPSL--KRKLLDNIDGGSLAKRLQF 338
+ + L E P+L KRK + ++ G L K+L F
Sbjct: 311 NCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF 346
>X77303-1|CAA54508.1| 346|Homo sapiens Cdk-activating kinase
protein.
Length = 346
Score = 482 bits (1189), Expect = e-136
Identities = 229/336 (68%), Positives = 273/336 (81%), Gaps = 4/336 (1%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RYEK+DFLGEGQFATVYKA+D T++IVA+KKIK+G R EA+DGINRTALREIKLLQEL
Sbjct: 11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N+IGLLD FG KSN+SLVFDFM+TDLE+IIKDN++VLTP+++KAYM+MTL+GLEYLHQ
Sbjct: 71 HPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQ 130
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+WILHRDLKPN LL++ G+LK+ DFGLAK+FGSP R THQVVTRWYRAPELLFGAR Y
Sbjct: 131 HWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMY 190
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFK 246
G GVDMWAVGCILAELLLRVPFLPG+SDLDQL+RIF+ GTPTEE WP M +L DYV FK
Sbjct: 191 GVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFK 250
Query: 247 LFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLPMP 306
FP L HIFSAA +DL+ L++ L P R TQAL+M YFS++P P+ G +LP P
Sbjct: 251 SFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRP 310
Query: 307 S-NISKL-EVEKPSL--KRKLLDNIDGGSLAKRLQF 338
+ + L E P+L KRK + ++ G L K+L F
Sbjct: 311 NCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF 346
>L20320-1|AAA36657.1| 346|Homo sapiens protein serine/threonine
kinase protein.
Length = 346
Score = 482 bits (1189), Expect = e-136
Identities = 229/336 (68%), Positives = 273/336 (81%), Gaps = 4/336 (1%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RYEK+DFLGEGQFATVYKA+D T++IVA+KKIK+G R EA+DGINRTALREIKLLQEL
Sbjct: 11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N+IGLLD FG KSN+SLVFDFM+TDLE+IIKDN++VLTP+++KAYM+MTL+GLEYLHQ
Sbjct: 71 HPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQ 130
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+WILHRDLKPN LL++ G+LK+ DFGLAK+FGSP R THQVVTRWYRAPELLFGAR Y
Sbjct: 131 HWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMY 190
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFK 246
G GVDMWAVGCILAELLLRVPFLPG+SDLDQL+RIF+ GTPTEE WP M +L DYV FK
Sbjct: 191 GVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFK 250
Query: 247 LFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLPMP 306
FP L HIFSAA +DL+ L++ L P R TQAL+M YFS++P P+ G +LP P
Sbjct: 251 SFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRP 310
Query: 307 S-NISKL-EVEKPSL--KRKLLDNIDGGSLAKRLQF 338
+ + L E P+L KRK + ++ G L K+L F
Sbjct: 311 NCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF 346
>BC000834-1|AAH00834.1| 346|Homo sapiens cyclin-dependent kinase 7
(MO15 homolog, Xenopus laevis, cdk-activating kinase)
protein.
Length = 346
Score = 482 bits (1189), Expect = e-136
Identities = 229/336 (68%), Positives = 273/336 (81%), Gaps = 4/336 (1%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RYEK+DFLGEGQFATVYKA+D T++IVA+KKIK+G R EA+DGINRTALREIKLLQEL
Sbjct: 11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N+IGLLD FG KSN+SLVFDFM+TDLE+IIKDN++VLTP+++KAYM+MTL+GLEYLHQ
Sbjct: 71 HPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQ 130
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+WILHRDLKPN LL++ G+LK+ DFGLAK+FGSP R THQVVTRWYRAPELLFGAR Y
Sbjct: 131 HWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMY 190
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFK 246
G GVDMWAVGCILAELLLRVPFLPG+SDLDQL+RIF+ GTPTEE WP M +L DYV FK
Sbjct: 191 GVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFK 250
Query: 247 LFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLPMP 306
FP L HIFSAA +DL+ L++ L P R TQAL+M YFS++P P+ G +LP P
Sbjct: 251 SFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRP 310
Query: 307 S-NISKL-EVEKPSL--KRKLLDNIDGGSLAKRLQF 338
+ + L E P+L KRK + ++ G L K+L F
Sbjct: 311 NCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF 346
>AY130859-1|AAM77799.1| 346|Homo sapiens cyclin-dependent kinase 7
protein.
Length = 346
Score = 482 bits (1189), Expect = e-136
Identities = 229/336 (68%), Positives = 273/336 (81%), Gaps = 4/336 (1%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RYEK+DFLGEGQFATVYKA+D T++IVA+KKIK+G R EA+DGINRTALREIKLLQEL
Sbjct: 11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N+IGLLD FG KSN+SLVFDFM+TDLE+IIKDN++VLTP+++KAYM+MTL+GLEYLHQ
Sbjct: 71 HPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQ 130
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+WILHRDLKPN LL++ G+LK+ DFGLAK+FGSP R THQVVTRWYRAPELLFGAR Y
Sbjct: 131 HWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMY 190
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFK 246
G GVDMWAVGCILAELLLRVPFLPG+SDLDQL+RIF+ GTPTEE WP M +L DYV FK
Sbjct: 191 GVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFK 250
Query: 247 LFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLPMP 306
FP L HIFSAA +DL+ L++ L P R TQAL+M YFS++P P+ G +LP P
Sbjct: 251 SFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRP 310
Query: 307 S-NISKL-EVEKPSL--KRKLLDNIDGGSLAKRLQF 338
+ + L E P+L KRK + ++ G L K+L F
Sbjct: 311 NCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF 346
>BC005298-1|AAH05298.1| 346|Homo sapiens cyclin-dependent kinase 7
(MO15 homolog, Xenopus laevis, cdk-activating kinase)
protein.
Length = 346
Score = 481 bits (1185), Expect = e-135
Identities = 228/336 (67%), Positives = 273/336 (81%), Gaps = 4/336 (1%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RYEK+DFLGEGQFATVYKA+D T++IVA+KKIK+G R EA+DGINRTALREIKLLQEL
Sbjct: 11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N+IGLLD FG KSN+SLVFDFM+TDLE+IIKDN++VLTP+++KAYM+MTL+GLEYLH+
Sbjct: 71 HPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHR 130
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+WILHRDLKPN LL++ G+LK+ DFGLAK+FGSP R THQVVTRWYRAPELLFGAR Y
Sbjct: 131 HWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMY 190
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFK 246
G GVDMWAVGCILAELLLRVPFLPG+SDLDQL+RIF+ GTPTEE WP M +L DYV FK
Sbjct: 191 GVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFK 250
Query: 247 LFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLPMP 306
FP L HIFSAA +DL+ L++ L P R TQAL+M YFS++P P+ G +LP P
Sbjct: 251 SFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRP 310
Query: 307 S-NISKL-EVEKPSL--KRKLLDNIDGGSLAKRLQF 338
+ + L E P+L KRK + ++ G L K+L F
Sbjct: 311 NCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF 346
>Y13120-1|CAA73587.1| 346|Homo sapiens serine/threonine protein
kinase protein.
Length = 346
Score = 479 bits (1180), Expect = e-135
Identities = 228/336 (67%), Positives = 272/336 (80%), Gaps = 4/336 (1%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RYEK+DFLGEGQFATVYKA+D T++IVA+KKIK+G R EA+DGINRTALREIKLLQEL
Sbjct: 11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELS 70
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N+IGLLD FG KSN+SLVFDFM+TDLE+IIKDN++VLTP+++KAYM+MTL+GLEYLHQ
Sbjct: 71 HPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQ 130
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+WILHRDLKPN LL++ G+LK+ DFGLAK+FGSP R THQVVTRWYRAPELLFGAR Y
Sbjct: 131 HWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMY 190
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFK 246
G GVDMWAVGCILAELLLRVPFLPG+SDLDQL+RIF+ GTPTEE WP M +L DYV K
Sbjct: 191 GVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTCK 250
Query: 247 LFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLPMP 306
FP L HIFSAA +DL+ L++ L P R TQAL+M YFS++P P+ G +LP P
Sbjct: 251 SFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRP 310
Query: 307 S-NISKL-EVEKPSL--KRKLLDNIDGGSLAKRLQF 338
+ + L E P+L KRK + ++ G L K+L F
Sbjct: 311 NCPVETLKEQANPALAIKRKRTEALEQGGLPKKLIF 346
>X61622-1|CAA43807.1| 298|Homo sapiens CDK2 protein.
Length = 298
Score = 256 bits (627), Expect = 8e-68
Identities = 125/294 (42%), Positives = 185/294 (62%), Gaps = 7/294 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++K++ +GEG + VYKA++ T ++VA+KKI++ + E G+ TA+REI LL+EL H
Sbjct: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETE---GVPSTAIREISLLKELNH 60
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMIMTLKGLEYLHQ 126
N++ LLDV ++ + LVF+F+ DL+ + + + P +K+Y+ L+GL + H
Sbjct: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+ +LHRDLKP LLIN EG +K+ DFGLA+AFG P R TH+VVT WYRAPE+L G++ Y
Sbjct: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGSKYY 180
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDY-VQF 245
T VD+W++GCI AE++ R PG+S++DQL RIF+ GTP E WPG+ ++ DY F
Sbjct: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF 240
Query: 246 KLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS--SKPAP 297
+ Q+ + ED LL +L P R AL +F +KP P
Sbjct: 241 PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP 294
>X66364-1|CAA47007.1| 292|Homo sapiens serine/threonine protein
kinase protein.
Length = 292
Score = 256 bits (626), Expect = 1e-67
Identities = 130/288 (45%), Positives = 181/288 (62%), Gaps = 5/288 (1%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
+YEK++ +GEG + TV+KAK+ +T +IVA+K++++ + +G+ +ALREI LL+EL+
Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLD---DDDEGVPSSALREICLLKELK 59
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N++ L DV ++LVF+F D DL+ L P VK+++ LKGL + H
Sbjct: 60 HKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHS 119
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+LHRDLKP LLINR G LK+ DFGLA+AFG P R + +VVT WYR P++LFGA+ Y
Sbjct: 120 RNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLY 179
Query: 187 GTGVDMWAVGCILAELL-LRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQF 245
T +DMW+ GCI AEL P PG DQL RIF++ GTPTEE WP M L DY +
Sbjct: 180 STSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPY 239
Query: 246 KLFPA-QELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS 292
++PA L ++ + LL++LL P R +ALQ YFS
Sbjct: 240 PMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFS 287
>M68520-1|AAA35667.1| 298|Homo sapiens cdc2-related protein kinase
protein.
Length = 298
Score = 256 bits (626), Expect = 1e-67
Identities = 125/294 (42%), Positives = 184/294 (62%), Gaps = 7/294 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++K++ +GEG + VYKA++ T ++VA+KKI++ + E G+ TA+REI LL+EL H
Sbjct: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETE---GVPSTAIREISLLKELNH 60
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMIMTLKGLEYLHQ 126
N++ LLDV ++ + LVF+F+ DL+ + + + P +K+Y+ L+GL + H
Sbjct: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+ +LHRDLKP LLIN EG +K+ DFGLA+AFG P R TH+VVT WYRAPE+L G + Y
Sbjct: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDY-VQF 245
T VD+W++GCI AE++ R PG+S++DQL RIF+ GTP E WPG+ ++ DY F
Sbjct: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF 240
Query: 246 KLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS--SKPAP 297
+ Q+ + ED LL +L P R AL +F +KP P
Sbjct: 241 PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP 294
>BT006821-1|AAP35467.1| 298|Homo sapiens cyclin-dependent kinase 2
protein.
Length = 298
Score = 256 bits (626), Expect = 1e-67
Identities = 125/294 (42%), Positives = 184/294 (62%), Gaps = 7/294 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++K++ +GEG + VYKA++ T ++VA+KKI++ + E G+ TA+REI LL+EL H
Sbjct: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETE---GVPSTAIREISLLKELNH 60
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMIMTLKGLEYLHQ 126
N++ LLDV ++ + LVF+F+ DL+ + + + P +K+Y+ L+GL + H
Sbjct: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+ +LHRDLKP LLIN EG +K+ DFGLA+AFG P R TH+VVT WYRAPE+L G + Y
Sbjct: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDY-VQF 245
T VD+W++GCI AE++ R PG+S++DQL RIF+ GTP E WPG+ ++ DY F
Sbjct: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF 240
Query: 246 KLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS--SKPAP 297
+ Q+ + ED LL +L P R AL +F +KP P
Sbjct: 241 PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP 294
>BT006680-1|AAP35326.1| 292|Homo sapiens cyclin-dependent kinase 5
protein.
Length = 292
Score = 256 bits (626), Expect = 1e-67
Identities = 130/288 (45%), Positives = 181/288 (62%), Gaps = 5/288 (1%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
+YEK++ +GEG + TV+KAK+ +T +IVA+K++++ + +G+ +ALREI LL+EL+
Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLD---DDDEGVPSSALREICLLKELK 59
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N++ L DV ++LVF+F D DL+ L P VK+++ LKGL + H
Sbjct: 60 HKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHS 119
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+LHRDLKP LLINR G LK+ DFGLA+AFG P R + +VVT WYR P++LFGA+ Y
Sbjct: 120 RNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLY 179
Query: 187 GTGVDMWAVGCILAELL-LRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQF 245
T +DMW+ GCI AEL P PG DQL RIF++ GTPTEE WP M L DY +
Sbjct: 180 STSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPY 239
Query: 246 KLFPA-QELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS 292
++PA L ++ + LL++LL P R +ALQ YFS
Sbjct: 240 PMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFS 287
>BC005115-1|AAH05115.1| 292|Homo sapiens cyclin-dependent kinase 5
protein.
Length = 292
Score = 256 bits (626), Expect = 1e-67
Identities = 130/288 (45%), Positives = 181/288 (62%), Gaps = 5/288 (1%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
+YEK++ +GEG + TV+KAK+ +T +IVA+K++++ + +G+ +ALREI LL+EL+
Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLD---DDDEGVPSSALREICLLKELK 59
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N++ L DV ++LVF+F D DL+ L P VK+++ LKGL + H
Sbjct: 60 HKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHS 119
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+LHRDLKP LLINR G LK+ DFGLA+AFG P R + +VVT WYR P++LFGA+ Y
Sbjct: 120 RNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLY 179
Query: 187 GTGVDMWAVGCILAELL-LRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQF 245
T +DMW+ GCI AEL P PG DQL RIF++ GTPTEE WP M L DY +
Sbjct: 180 STSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPY 239
Query: 246 KLFPA-QELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS 292
++PA L ++ + LL++LL P R +ALQ YFS
Sbjct: 240 PMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFS 287
>BC003065-1|AAH03065.1| 298|Homo sapiens cyclin-dependent kinase 2
protein.
Length = 298
Score = 256 bits (626), Expect = 1e-67
Identities = 125/294 (42%), Positives = 184/294 (62%), Gaps = 7/294 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++K++ +GEG + VYKA++ T ++VA+KKI++ + E G+ TA+REI LL+EL H
Sbjct: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETE---GVPSTAIREISLLKELNH 60
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMIMTLKGLEYLHQ 126
N++ LLDV ++ + LVF+F+ DL+ + + + P +K+Y+ L+GL + H
Sbjct: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+ +LHRDLKP LLIN EG +K+ DFGLA+AFG P R TH+VVT WYRAPE+L G + Y
Sbjct: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDY-VQF 245
T VD+W++GCI AE++ R PG+S++DQL RIF+ GTP E WPG+ ++ DY F
Sbjct: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF 240
Query: 246 KLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS--SKPAP 297
+ Q+ + ED LL +L P R AL +F +KP P
Sbjct: 241 PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP 294
>AY049778-1|AAL15435.1| 292|Homo sapiens cyclin-dependent kinase 5
protein.
Length = 292
Score = 256 bits (626), Expect = 1e-67
Identities = 130/288 (45%), Positives = 181/288 (62%), Gaps = 5/288 (1%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
+YEK++ +GEG + TV+KAK+ +T +IVA+K++++ + +G+ +ALREI LL+EL+
Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLD---DDDEGVPSSALREICLLKELK 59
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N++ L DV ++LVF+F D DL+ L P VK+++ LKGL + H
Sbjct: 60 HKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHS 119
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+LHRDLKP LLINR G LK+ DFGLA+AFG P R + +VVT WYR P++LFGA+ Y
Sbjct: 120 RNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLY 179
Query: 187 GTGVDMWAVGCILAELL-LRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQF 245
T +DMW+ GCI AEL P PG DQL RIF++ GTPTEE WP M L DY +
Sbjct: 180 STSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPY 239
Query: 246 KLFPA-QELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS 292
++PA L ++ + LL++LL P R +ALQ YFS
Sbjct: 240 PMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFS 287
>AF512553-1|AAM34794.1| 298|Homo sapiens cyclin-dependent kinase 2
protein.
Length = 298
Score = 256 bits (626), Expect = 1e-67
Identities = 125/294 (42%), Positives = 184/294 (62%), Gaps = 7/294 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++K++ +GEG + VYKA++ T ++VA+KKI++ + E G+ TA+REI LL+EL H
Sbjct: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETE---GVPSTAIREISLLKELNH 60
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMIMTLKGLEYLHQ 126
N++ LLDV ++ + LVF+F+ DL+ + + + P +K+Y+ L+GL + H
Sbjct: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+ +LHRDLKP LLIN EG +K+ DFGLA+AFG P R TH+VVT WYRAPE+L G + Y
Sbjct: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDY-VQF 245
T VD+W++GCI AE++ R PG+S++DQL RIF+ GTP E WPG+ ++ DY F
Sbjct: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF 240
Query: 246 KLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS--SKPAP 297
+ Q+ + ED LL +L P R AL +F +KP P
Sbjct: 241 PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP 294
>X66357-1|CAA47001.1| 305|Homo sapiens serine/threonine protein
kinase protein.
Length = 305
Score = 254 bits (623), Expect = 2e-67
Identities = 127/293 (43%), Positives = 186/293 (63%), Gaps = 6/293 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++K++ +GEG + VYKAK+ +T ++VA+KKI++ +E G+ TA+REI LL+EL+H
Sbjct: 4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEME---GVPSTAIREISLLKELKH 60
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMIMTLKGLEYLHQ 126
N++ LLDV + + LVF+F+ DL+ + P + +K+Y+ L+G+ + H
Sbjct: 61 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS 120
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+ ++HRDLKP LLIN G +K+ DFGLA+AFG P R TH+VVT WYRAPE+L G++ Y
Sbjct: 121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYV-QF 245
T VD+W++GCI AE++ R PG+S++DQL RIF++ GTP+E+ WPG+ L DY F
Sbjct: 181 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSF 240
Query: 246 KLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPS 298
+ + L I + LL LL P R AL YFSS P PS
Sbjct: 241 PKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSS-PEPS 292
>X62071-1|CAA43985.1| 298|Homo sapiens cdk2 protein.
Length = 298
Score = 254 bits (623), Expect = 2e-67
Identities = 125/294 (42%), Positives = 183/294 (62%), Gaps = 7/294 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++K++ +GEG + VYKA++ T ++VA+KKI+ + E G+ TA+REI LL+EL H
Sbjct: 4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRXDTETE---GVPSTAIREISLLKELNH 60
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMIMTLKGLEYLHQ 126
N++ LLDV ++ + LVF+F+ DL+ + + + P +K+Y+ L+GL + H
Sbjct: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+ +LHRDLKP LLIN EG +K+ DFGLA+AFG P R TH+VVT WYRAPE+L G + Y
Sbjct: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDY-VQF 245
T VD+W++GCI AE++ R PG+S++DQL RIF+ GTP E WPG+ ++ DY F
Sbjct: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF 240
Query: 246 KLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS--SKPAP 297
+ Q+ + ED LL +L P R AL +F +KP P
Sbjct: 241 PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP 294
>AY789470-1|AAV40830.1| 305|Homo sapiens cyclin-dependent kinase 3
protein.
Length = 305
Score = 254 bits (623), Expect = 2e-67
Identities = 127/293 (43%), Positives = 186/293 (63%), Gaps = 6/293 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++K++ +GEG + VYKAK+ +T ++VA+KKI++ +E G+ TA+REI LL+EL+H
Sbjct: 4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEME---GVPSTAIREISLLKELKH 60
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMIMTLKGLEYLHQ 126
N++ LLDV + + LVF+F+ DL+ + P + +K+Y+ L+G+ + H
Sbjct: 61 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS 120
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+ ++HRDLKP LLIN G +K+ DFGLA+AFG P R TH+VVT WYRAPE+L G++ Y
Sbjct: 121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYV-QF 245
T VD+W++GCI AE++ R PG+S++DQL RIF++ GTP+E+ WPG+ L DY F
Sbjct: 181 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSF 240
Query: 246 KLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPS 298
+ + L I + LL LL P R AL YFSS P PS
Sbjct: 241 PKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSS-PEPS 292
>CR457041-1|CAG33322.1| 292|Homo sapiens CDK5 protein.
Length = 292
Score = 253 bits (619), Expect = 8e-67
Identities = 129/288 (44%), Positives = 180/288 (62%), Gaps = 5/288 (1%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
+YEK++ +GEG + TV+KAK+ +T +IVA+K++++ + +G+ +ALREI LL+EL+
Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLD---DDDEGVPSSALREICLLKELK 59
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N++ L DV ++LVF+F D DL+ L P VK+++ LKGL + H
Sbjct: 60 HKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHS 119
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+LHRDLKP LINR G LK+ DFGLA+AFG P R + +VVT WYR P++LFGA+ Y
Sbjct: 120 RNVLHRDLKPQNPLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLY 179
Query: 187 GTGVDMWAVGCILAELL-LRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQF 245
T +DMW+ GCI AEL P PG DQL RIF++ GTPTEE WP M L DY +
Sbjct: 180 STSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPY 239
Query: 246 KLFPA-QELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS 292
++PA L ++ + LL++LL P R +ALQ YFS
Sbjct: 240 PMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFS 287
>BC110905-1|AAI10906.1| 397|Homo sapiens cell division cycle 2-like
2 (PITSLRE proteins) protein.
Length = 397
Score = 246 bits (601), Expect = 1e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 40 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 96
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 97 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 156
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 157 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 216
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 217 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 276
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 277 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 336
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 337 FPTWPAKSEQQRVK 350
>BC094827-1|AAH94827.1| 475|Homo sapiens CDC2L2 protein protein.
Length = 475
Score = 246 bits (601), Expect = 1e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 118 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 174
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 175 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 234
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 235 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 294
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 295 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 354
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 355 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 414
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 415 FPTWPAKSEQQRVK 428
>BC014464-1|AAH14464.1| 464|Homo sapiens CDC2L2 protein protein.
Length = 464
Score = 246 bits (601), Expect = 1e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 107 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 163
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 164 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 223
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 224 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 283
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 284 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 343
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 344 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 403
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 404 FPTWPAKSEQQRVK 417
>AL031282-7|CAI20032.1| 783|Homo sapiens cell division cycle 2-like
2 (PITSLRE proteins) protein.
Length = 783
Score = 246 bits (601), Expect = 1e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 426 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 482
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 483 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 542
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 543 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 602
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 603 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 662
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 663 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 722
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 723 FPTWPAKSEQQRVK 736
>AL031282-6|CAI20034.1| 780|Homo sapiens cell division cycle 2-like
2 (PITSLRE proteins) protein.
Length = 780
Score = 246 bits (601), Expect = 1e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 423 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 479
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 539
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 540 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 599
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 600 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 659
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 660 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 719
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 720 FPTWPAKSEQQRVK 733
>AL031282-5|CAI20031.1| 779|Homo sapiens cell division cycle 2-like
2 (PITSLRE proteins) protein.
Length = 779
Score = 246 bits (601), Expect = 1e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 422 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 478
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 479 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 538
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 539 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 598
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 599 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 658
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 659 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 718
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 719 FPTWPAKSEQQRVK 732
>AL031282-4|CAI20033.1| 770|Homo sapiens cell division cycle 2-like
2 (PITSLRE proteins) protein.
Length = 770
Score = 246 bits (601), Expect = 1e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 413 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 469
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 470 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 529
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 530 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 589
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 590 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 649
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 650 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 709
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 710 FPTWPAKSEQQRVK 723
>AL031282-3|CAI20030.1| 746|Homo sapiens cell division cycle 2-like
2 (PITSLRE proteins) protein.
Length = 746
Score = 246 bits (601), Expect = 1e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 389 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 445
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 446 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 505
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 506 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 565
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 566 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 625
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 626 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 685
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 686 FPTWPAKSEQQRVK 699
>AF080694-4|AAC95300.1| 768|Homo sapiens PITSLRE protein kinase
beta SV3 isoform protein.
Length = 768
Score = 246 bits (601), Expect = 1e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 411 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 467
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 468 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 527
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 528 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 587
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 588 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 647
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 648 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 707
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 708 FPTWPAKSEQQRVK 721
>AF080694-3|AAC95298.1| 781|Homo sapiens PITSLRE protein kinase
beta SV6 isoform protein.
Length = 781
Score = 246 bits (601), Expect = 1e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 424 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 480
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 481 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 540
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 541 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 600
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 601 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 660
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 661 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 720
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 721 FPTWPAKSEQQRVK 734
>AF080694-2|AAC95297.1| 777|Homo sapiens PITSLRE protein kinase
beta SV2 isoform protein.
Length = 777
Score = 246 bits (601), Expect = 1e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 420 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 476
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 477 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 536
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 537 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 596
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 597 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 656
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 657 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 716
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 717 FPTWPAKSEQQRVK 730
>AF080694-1|AAC95299.1| 778|Homo sapiens PITSLRE protein kinase
beta SV1 isoform protein.
Length = 778
Score = 246 bits (601), Expect = 1e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 421 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 477
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 478 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 537
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 538 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 597
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 598 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 657
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 658 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 717
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 718 FPTWPAKSEQQRVK 731
>AF067523-1|AAC72088.1| 397|Homo sapiens PITSLRE protein kinase
beta SV7 isoform protein.
Length = 397
Score = 246 bits (601), Expect = 1e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 40 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 96
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 97 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 156
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 157 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 216
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 217 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 276
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 277 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 336
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 337 FPTWPAKSEQQRVK 350
>AF067522-1|AAC72087.1| 780|Homo sapiens PITSLRE protein kinase
beta SV6 isoform protein.
Length = 780
Score = 246 bits (601), Expect = 1e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 423 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 479
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 539
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 540 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 599
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 600 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 659
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 660 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 719
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 720 FPTWPAKSEQQRVK 733
>AF067521-1|AAC72086.1| 767|Homo sapiens PITSLRE protein kinase
beta SV3 isoform protein.
Length = 767
Score = 246 bits (601), Expect = 1e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 410 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 466
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 467 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 526
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 527 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 586
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 587 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 646
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 647 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 706
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 707 FPTWPAKSEQQRVK 720
>AF067520-1|AAC72085.1| 776|Homo sapiens PITSLRE protein kinase
beta SV2 isoform protein.
Length = 776
Score = 246 bits (601), Expect = 1e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 419 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 475
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 476 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 535
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 536 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 595
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 596 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 655
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 656 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 715
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 716 FPTWPAKSEQQRVK 729
>AF067519-1|AAC72084.1| 777|Homo sapiens PITSLRE protein kinase
beta SV1 isoform protein.
Length = 777
Score = 246 bits (601), Expect = 1e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 420 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 476
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 477 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 536
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 537 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 596
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 597 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 656
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 657 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 716
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 717 FPTWPAKSEQQRVK 730
>AF067518-1|AAC72083.1| 397|Homo sapiens PITSLRE protein kinase
beta SV8 isoform protein.
Length = 397
Score = 246 bits (601), Expect = 1e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 40 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 96
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 97 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 156
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 157 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 216
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 217 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 276
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 277 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 336
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 337 FPTWPAKSEQQRVK 350
>U07705-1|AAA19595.1| 775|Homo sapiens PITSLRE isoform PBETA22
protein.
Length = 775
Score = 245 bits (599), Expect = 2e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 418 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENE---GFPITSLREINTILKAQH 474
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 475 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 534
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 535 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 594
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 595 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 654
Query: 244 QFKLFPAQELRHIFSA-ASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A SE L+ L +P R L+ YF P PS+
Sbjct: 655 TFSRHPYNNLRKRFGALLSEQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 714
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 715 FPTWPAKSEQQRVK 728
>U07704-1|AAA19594.1| 777|Homo sapiens PITSLRE isoform PBETA21
protein.
Length = 777
Score = 245 bits (599), Expect = 2e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 420 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENE---GFPITSLREINTILKAQH 476
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 477 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 536
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 537 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 596
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 597 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 656
Query: 244 QFKLFPAQELRHIFSA-ASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A SE L+ L +P R L+ YF P PS+
Sbjct: 657 TFSRHPYNNLRKRFGALLSEQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 716
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 717 FPTWPAKSEQQRVK 730
>U04824-1|AAA19586.1| 779|Homo sapiens PITSLRE alpha 2-1 protein.
Length = 779
Score = 245 bits (599), Expect = 2e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 422 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 478
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 479 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 538
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT WYRAPELL GA++
Sbjct: 539 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 598
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 599 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 658
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 659 TFSRHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 718
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 719 FPTWPAKSEQQRVK 732
>U04819-1|AAA19585.1| 439|Homo sapiens PITSLRE beta 1 protein.
Length = 439
Score = 245 bits (599), Expect = 2e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 82 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENE---GFPITSLREINTILKAQH 138
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 139 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 198
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 199 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 258
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 259 YSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKM 318
Query: 244 QFKLFPAQELRHIFSA-ASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A SE L+ L +P R L+ YF P PS+
Sbjct: 319 TFSRHPYNNLRKRFGALLSEQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 378
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 379 FPTWPAKSEQQRVK 392
>U04818-1|AAA19584.1| 562|Homo sapiens PITSLRE alpha 2-4 protein.
Length = 562
Score = 245 bits (599), Expect = 2e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 205 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 261
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 262 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 321
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT WYRAPELL GA++
Sbjct: 322 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 381
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 382 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 441
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 442 TFSRHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 501
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 502 FPTWPAKSEQQRVK 515
>U04817-1|AAA19583.1| 768|Homo sapiens PITSLRE alpha 2-3 protein.
Length = 768
Score = 245 bits (599), Expect = 2e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 411 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 467
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 468 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 527
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT WYRAPELL GA++
Sbjct: 528 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 587
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 588 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 647
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 648 TFSRHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 707
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 708 FPTWPAKSEQQRVK 721
>U04816-1|AAA19582.1| 777|Homo sapiens PITSLRE alpha 2-2 protein.
Length = 777
Score = 245 bits (599), Expect = 2e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 420 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 476
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 477 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 536
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT WYRAPELL GA++
Sbjct: 537 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 596
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 597 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 656
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 657 TFSRHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 716
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 717 FPTWPAKSEQQRVK 730
>U04815-1|AAA19581.1| 461|Homo sapiens PITSLRE alpha 1 protein.
Length = 461
Score = 245 bits (599), Expect = 2e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 104 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 160
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 161 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 220
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT WYRAPELL GA++
Sbjct: 221 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 280
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 281 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 340
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 341 TFSRHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 400
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 401 FPTWPAKSEQQRVK 414
>M88563-1|AAB59449.1| 446|Homo sapiens p58 protein kinase protein.
Length = 446
Score = 245 bits (599), Expect = 2e-64
Identities = 124/314 (39%), Positives = 188/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 89 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 145
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 146 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 205
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT+WYRAPELL GA++
Sbjct: 206 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 265
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 266 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 325
Query: 244 QFKLFPAQELRHIFSA-ASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A SE L+ L +P R L+ YF P PS+
Sbjct: 326 TFSEHPYNNLRKRFGALLSEQGFDLMNKFLTYFPGRRLSAQDGLKHEYFRETPLPIDPSM 385
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 386 FPTWPAKSEQQRVK 399
>M37712-1|AAA36406.1| 439|Homo sapiens p58/GTA protein kinase
protein.
Length = 439
Score = 244 bits (598), Expect = 3e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 82 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 138
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 139 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 198
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT WYRAPELL GA++
Sbjct: 199 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 258
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 259 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 318
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 319 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 378
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 379 FPTWPAKSEQQRVK 392
>BC139777-1|AAI39778.1| 542|Homo sapiens CDC2L1 protein protein.
Length = 542
Score = 244 bits (598), Expect = 3e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 185 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 241
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 242 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 301
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT WYRAPELL GA++
Sbjct: 302 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 361
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 362 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 421
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 422 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 481
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 482 FPTWPAKSEQQRVK 495
>BC062579-1|AAH62579.1| 475|Homo sapiens CDC2L1 protein protein.
Length = 475
Score = 244 bits (598), Expect = 3e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 118 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 174
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 175 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 234
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT WYRAPELL GA++
Sbjct: 235 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 294
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 295 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 354
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 355 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 414
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 415 FPTWPAKSEQQRVK 428
>BC033069-1|AAH33069.1| 508|Homo sapiens CDC2L1 protein protein.
Length = 508
Score = 244 bits (598), Expect = 3e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 151 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 207
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 208 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 267
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT WYRAPELL GA++
Sbjct: 268 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 327
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 328 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 387
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 388 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 447
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 448 FPTWPAKSEQQRVK 461
>AF080683-5|AAC83666.1| 565|Homo sapiens PITSLRE protein kinase
alpha SV11 isoform protein.
Length = 565
Score = 244 bits (598), Expect = 3e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 208 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 264
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 265 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 324
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT WYRAPELL GA++
Sbjct: 325 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 384
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 385 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 444
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 445 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 504
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 505 FPTWPAKSEQQRVK 518
>AF080683-4|AAC83663.1| 738|Homo sapiens PITSLRE protein kinase
alpha SV5 isoform protein.
Length = 738
Score = 244 bits (598), Expect = 3e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 381 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 437
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 438 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 497
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT WYRAPELL GA++
Sbjct: 498 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 557
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 558 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 617
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 618 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 677
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 678 FPTWPAKSEQQRVK 691
>AF080683-3|AAC83665.1| 748|Homo sapiens PITSLRE protein kinase
alpha SV10 isoform protein.
Length = 748
Score = 244 bits (598), Expect = 3e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 391 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 447
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 448 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 507
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT WYRAPELL GA++
Sbjct: 508 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 567
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 568 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 627
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 628 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 687
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 688 FPTWPAKSEQQRVK 701
>AF080683-2|AAC83662.1| 782|Homo sapiens PITSLRE protein kinase
alpha SV1 isoform protein.
Length = 782
Score = 244 bits (598), Expect = 3e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 425 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 481
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 482 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 541
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT WYRAPELL GA++
Sbjct: 542 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 601
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 602 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 661
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 662 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 721
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 722 FPTWPAKSEQQRVK 735
>AF080683-1|AAC83664.1| 755|Homo sapiens PITSLRE protein kinase
alpha SV9 isoform protein.
Length = 755
Score = 244 bits (598), Expect = 3e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 398 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 454
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 455 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 514
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT WYRAPELL GA++
Sbjct: 515 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 574
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 575 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 634
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 635 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 694
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 695 FPTWPAKSEQQRVK 708
>AF067517-1|AAC72082.1| 565|Homo sapiens PITSLRE protein kinase
alpha SV11 isoform protein.
Length = 565
Score = 244 bits (598), Expect = 3e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 208 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 264
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 265 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 324
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT WYRAPELL GA++
Sbjct: 325 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 384
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 385 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 444
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 445 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 504
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 505 FPTWPAKSEQQRVK 518
>AF067516-1|AAC72081.1| 748|Homo sapiens PITSLRE protein kinase
alpha SV10 isoform protein.
Length = 748
Score = 244 bits (598), Expect = 3e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 391 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 447
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 448 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 507
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT WYRAPELL GA++
Sbjct: 508 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 567
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 568 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 627
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 628 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 687
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 688 FPTWPAKSEQQRVK 701
>AF067515-1|AAC72080.1| 795|Homo sapiens PITSLRE protein kinase
alpha SV9 isoform protein.
Length = 795
Score = 244 bits (598), Expect = 3e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 438 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 494
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 495 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 554
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT WYRAPELL GA++
Sbjct: 555 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 614
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 615 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 674
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 675 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 734
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 735 FPTWPAKSEQQRVK 748
>AF067514-1|AAC72079.1| 737|Homo sapiens PITSLRE protein kinase
alpha SV5 isoform protein.
Length = 737
Score = 244 bits (598), Expect = 3e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 380 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 436
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 437 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 496
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT WYRAPELL GA++
Sbjct: 497 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 556
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 557 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 616
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 617 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 676
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 677 FPTWPAKSEQQRVK 690
>AF067513-1|AAC72078.1| 526|Homo sapiens PITSLRE protein kinase
alpha SV4 isoform protein.
Length = 526
Score = 244 bits (598), Expect = 3e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 169 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 225
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 226 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 285
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT WYRAPELL GA++
Sbjct: 286 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 345
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 346 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 405
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 406 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 465
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 466 FPTWPAKSEQQRVK 479
>AF067512-1|AAC72077.1| 782|Homo sapiens PITSLRE protein kinase
alpha SV1 isoform protein.
Length = 782
Score = 244 bits (598), Expect = 3e-64
Identities = 124/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 425 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 481
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 482 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 541
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWILHRDLK + LL++ GILK+GDFGLA+ +GSP + T VVT WYRAPELL GA++
Sbjct: 542 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 601
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 602 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 661
Query: 244 QFKLFPAQELRHIFSAASEDLIF-LLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A D F L+ L +P R L+ YF P PS+
Sbjct: 662 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 721
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 722 FPTWPAKSEQQRVK 735
>X78342-1|CAA55137.1| 360|Homo sapiens PISSLRE protein.
Length = 360
Score = 241 bits (591), Expect = 2e-63
Identities = 125/301 (41%), Positives = 181/301 (60%), Gaps = 7/301 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
+EK++ +GEG + VY+A+D +TD+IVA+KK+++ +DGI ++LREI LL L+H
Sbjct: 39 FEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKE---KDGIPISSLREITLLLRLRH 95
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ L +V ++ LV + + DL ++++ + A VK ++ L+GL+YLH
Sbjct: 96 PNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLH 155
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
+N+I+HRDLK + LL+ +G +K DFGLA+A+G P + T +VVT WYRAPELL G
Sbjct: 156 RNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTT 215
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQF 245
T +DMWAVGCILAELL P LPG S++ Q+ I Q+ GTP+E WPG L Q+
Sbjct: 216 QTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQY 275
Query: 246 KL--FPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKL 303
L P L+H F SE + LL L P R L+ +YF KP P +
Sbjct: 276 SLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLPCEPELM 335
Query: 304 P 304
P
Sbjct: 336 P 336
>AL353572-4|CAM17657.1| 346|Homo sapiens cell cycle related kinase
protein.
Length = 346
Score = 241 bits (591), Expect = 2e-63
Identities = 133/301 (44%), Positives = 182/301 (60%), Gaps = 9/301 (2%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHIN-LIG 72
+GEG V+KAK +T +IVA+KK+ + RLE DG ALREIK LQE++ ++
Sbjct: 10 IGEGAHGIVFKAKHVETGEIVALKKVAL-RRLE--DGFPNQALREIKALQEMEDNQYVVQ 66
Query: 73 LLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQNWILHR 132
L VF L F+FM +DL +++ L A VK+Y+ M LKG+ + H N I+HR
Sbjct: 67 LKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHANNIVHR 126
Query: 133 DLKPNTLLINREGILKIGDFGLAKAFGSP-TRINTHQVVTRWYRAPELLFGARQYGTGVD 191
DLKP LLI+ G LKI DFGLA+ F +R+ THQV TRWYRAPELL+GARQY GVD
Sbjct: 127 DLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQYDQGVD 186
Query: 192 MWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDY--VQFKLFP 249
+W+VGCI+ ELL P PG++D++QL + ++ GTP + WP + L DY + FK
Sbjct: 187 LWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQV 246
Query: 250 AQELRHIFSAASEDLIFLLESLLALYPPN-RCDCTQALQMAYFSSKPAPSVGPKLPMPSN 308
L + S + LL L LYPP+ R ++AL YF + P P+ +LP+P
Sbjct: 247 PMPLEEVLPDVSPQALDLLGQFL-LYPPHQRIAASKALLHQYFFTAPLPAHPSELPIPQR 305
Query: 309 I 309
+
Sbjct: 306 L 306
>AJ010341-1|CAB37619.1| 360|Homo sapiens cyclin-dependent kinase
protein.
Length = 360
Score = 241 bits (591), Expect = 2e-63
Identities = 125/301 (41%), Positives = 181/301 (60%), Gaps = 7/301 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
+EK++ +GEG + VY+A+D +TD+IVA+KK+++ +DGI ++LREI LL L+H
Sbjct: 39 FEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKE---KDGIPISSLREITLLLRLRH 95
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ L +V ++ LV + + DL ++++ + A VK ++ L+GL+YLH
Sbjct: 96 PNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLH 155
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
+N+I+HRDLK + LL+ +G +K DFGLA+A+G P + T +VVT WYRAPELL G
Sbjct: 156 RNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTT 215
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQF 245
T +DMWAVGCILAELL P LPG S++ Q+ I Q+ GTP+E WPG L Q+
Sbjct: 216 QTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQY 275
Query: 246 KL--FPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKL 303
L P L+H F SE + LL L P R L+ +YF KP P +
Sbjct: 276 SLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLPCEPELM 335
Query: 304 P 304
P
Sbjct: 336 P 336
>AF547664-1|AAN28684.1| 346|Homo sapiens cell cycle related kinase
protein.
Length = 346
Score = 241 bits (591), Expect = 2e-63
Identities = 133/301 (44%), Positives = 182/301 (60%), Gaps = 9/301 (2%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHIN-LIG 72
+GEG V+KAK +T +IVA+KK+ + RLE DG ALREIK LQE++ ++
Sbjct: 10 IGEGAHGIVFKAKHVETGEIVALKKVAL-RRLE--DGFPNQALREIKALQEMEDNQYVVQ 66
Query: 73 LLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQNWILHR 132
L VF L F+FM +DL +++ L A VK+Y+ M LKG+ + H N I+HR
Sbjct: 67 LKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHANNIVHR 126
Query: 133 DLKPNTLLINREGILKIGDFGLAKAFGSP-TRINTHQVVTRWYRAPELLFGARQYGTGVD 191
DLKP LLI+ G LKI DFGLA+ F +R+ THQV TRWYRAPELL+GARQY GVD
Sbjct: 127 DLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQYDQGVD 186
Query: 192 MWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDY--VQFKLFP 249
+W+VGCI+ ELL P PG++D++QL + ++ GTP + WP + L DY + FK
Sbjct: 187 LWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQV 246
Query: 250 AQELRHIFSAASEDLIFLLESLLALYPPN-RCDCTQALQMAYFSSKPAPSVGPKLPMPSN 308
L + S + LL L LYPP+ R ++AL YF + P P+ +LP+P
Sbjct: 247 PMPLEEVLPDVSPQALDLLGQFL-LYPPHQRIAASKALLHQYFFTAPLPAHPSELPIPQR 305
Query: 309 I 309
+
Sbjct: 306 L 306
>AF174497-1|AAF36538.1| 565|Homo sapiens GR AF-1 coactivator 3
protein.
Length = 565
Score = 241 bits (590), Expect = 2e-63
Identities = 123/314 (39%), Positives = 187/314 (59%), Gaps = 11/314 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++ ++ + EG + VY+AKD KTD+IVA+K++K+ E G T+LREI + + QH
Sbjct: 208 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE---GFPITSLREINTILKAQH 264
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ + ++ + +V ++++ DL+ +++ P VK MI L+G+++LH
Sbjct: 265 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 324
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
NWIL RDLK +TLL++ GILK+GDFGLA+ +GSP + T VVT WYRAPELL GA++
Sbjct: 325 DNWILQRDLKTSTLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 384
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTL--TDYV 243
Y T VDMW+VGCI ELL + P PG+S++DQ++++F+ GTP+E+ WPG L +
Sbjct: 385 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM 444
Query: 244 QFKLFPAQELRHIFSA-ASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPA---PSV 299
F P LR F A S+ L+ L +P R L+ YF P PS+
Sbjct: 445 TFSRHPYNNLRKRFGALLSDQGCDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM 504
Query: 300 GPKLPMPSNISKLE 313
P P S +++
Sbjct: 505 FPTWPAKSEQQRVK 518
>L33264-1|AAA60092.2| 314|Homo sapiens CDC2-related protein kinase
protein.
Length = 314
Score = 239 bits (584), Expect = 1e-62
Identities = 123/292 (42%), Positives = 178/292 (60%), Gaps = 7/292 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
+EK++ +GEG + VY+A+D +TD+IVA+KK+++ +DGI ++LREI LL L+H
Sbjct: 10 FEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKE---KDGIPISSLREITLLLRLRH 66
Query: 68 INLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLH 125
N++ L +V ++ LV + + DL ++++ + A VK ++ L+GL+YLH
Sbjct: 67 PNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLH 126
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
+N+I+HRDLK + LL+ +G +K DFGLA+A+G P + T +VVT WYRAPELL G
Sbjct: 127 RNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTT 186
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQF 245
T +DMWAVGCILAELL P LPG S++ Q+ I Q+ GTP+E WPG L Q+
Sbjct: 187 QTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQY 246
Query: 246 KL--FPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKP 295
L P L+H F SE + LL L P R L+ +YF KP
Sbjct: 247 SLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKP 298
>AB020641-1|BAA74857.2| 453|Homo sapiens KIAA0834 protein protein.
Length = 453
Score = 238 bits (583), Expect = 2e-62
Identities = 126/293 (43%), Positives = 177/293 (60%), Gaps = 9/293 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
YEK++ LGEG +ATVYK K K+VA+K I RL+ ++G TA+RE LL+ L+H
Sbjct: 119 YEKLEKLGEGSYATVYKGKSKVNGKLVALKVI----RLQEEEGTPFTAIREASLLKGLKH 174
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ K ++LVF+++ TDL + + L P NVK ++ L+GL Y+HQ
Sbjct: 175 ANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQR 234
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
+ILHRDLKP LLI+ G LK+ DFGLA+A P+ +++VVT WYR P++L G+ +Y
Sbjct: 235 YILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYS 294
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDL-DQLSRIFQVFGTPTEENWPGMKTLTDY--VQ 244
T +DMW VGCI E++ V PG D+ DQL RIF V GTP E+ WPG+ +L + +
Sbjct: 295 TCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPER 354
Query: 245 FKLFPAQELRHIFSAAS--EDLIFLLESLLALYPPNRCDCTQALQMAYFSSKP 295
F L+ ++ LR ++ S L LL P NR AL YFS P
Sbjct: 355 FTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLP 407
>AF119833-1|AAG43234.1| 469|Homo sapiens serine/threonine protein
kinase PFTAIRE-1 protein.
Length = 469
Score = 237 bits (580), Expect = 4e-62
Identities = 126/293 (43%), Positives = 177/293 (60%), Gaps = 9/293 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
YEK++ LGEG +ATVYK K K+VA+K I RL+ ++G TA+RE LL+ L+H
Sbjct: 135 YEKLEKLGEGSYATVYKGKSKVNWKLVALKVI----RLQEEEGTPFTAIREASLLKGLKH 190
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ K ++LVF+++ TDL + + L P NVK ++ L+GL Y+HQ
Sbjct: 191 ANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQR 250
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
+ILHRDLKP LLI+ G LK+ DFGLA+A P+ +++VVT WYR P++L G+ +Y
Sbjct: 251 YILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYS 310
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDL-DQLSRIFQVFGTPTEENWPGMKTLTDY--VQ 244
T +DMW VGCI E++ V PG D+ DQL RIF V GTP E+ WPG+ +L + +
Sbjct: 311 TCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPER 370
Query: 245 FKLFPAQELRHIFSAAS--EDLIFLLESLLALYPPNRCDCTQALQMAYFSSKP 295
F L+ ++ LR ++ S L LL P NR AL YFS P
Sbjct: 371 FTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLP 423
>X66363-1|CAA47006.1| 496|Homo sapiens serine/threonine protein
kinase protein.
Length = 496
Score = 236 bits (577), Expect = 9e-62
Identities = 119/289 (41%), Positives = 175/289 (60%), Gaps = 8/289 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y K+D LGEG +ATVYK K TD +VA+K+I RLE ++G TA+RE+ LL++L+H
Sbjct: 165 YIKLDKLGEGTYATVYKGKSKLTDNLVALKEI----RLEHEEGAPCTAIREVSLLKDLKH 220
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ + +++LVF+++D DL+ + D ++ NVK ++ L+GL Y H+
Sbjct: 221 ANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQ 280
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
+LHRDLKP LLIN G LK+ DFGLA+A PT+ +++VVT WYR P++L G+ Y
Sbjct: 281 KVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYS 340
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFKL 247
T +DMW VGCI E+ P PG + +QL IF++ GTPTEE WPG+ + ++ +
Sbjct: 341 TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYN- 399
Query: 248 FPAQELRHIFSAA---SEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+P + S A D LL LL NR A++ +F S
Sbjct: 400 YPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLS 448
>BT006827-1|AAP35473.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 236 bits (577), Expect = 9e-62
Identities = 119/289 (41%), Positives = 175/289 (60%), Gaps = 8/289 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y K+D LGEG +ATVYK K TD +VA+K+I RLE ++G TA+RE+ LL++L+H
Sbjct: 165 YIKLDKLGEGTYATVYKGKSKLTDNLVALKEI----RLEHEEGAPCTAIREVSLLKDLKH 220
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ + +++LVF+++D DL+ + D ++ NVK ++ L+GL Y H+
Sbjct: 221 ANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQ 280
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
+LHRDLKP LLIN G LK+ DFGLA+A PT+ +++VVT WYR P++L G+ Y
Sbjct: 281 KVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYS 340
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFKL 247
T +DMW VGCI E+ P PG + +QL IF++ GTPTEE WPG+ + ++ +
Sbjct: 341 TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYN- 399
Query: 248 FPAQELRHIFSAA---SEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+P + S A D LL LL NR A++ +F S
Sbjct: 400 YPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLS 448
>BC015607-1|AAH15607.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 236 bits (577), Expect = 9e-62
Identities = 119/289 (41%), Positives = 175/289 (60%), Gaps = 8/289 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y K+D LGEG +ATVYK K TD +VA+K+I RLE ++G TA+RE+ LL++L+H
Sbjct: 165 YIKLDKLGEGTYATVYKGKSKLTDNLVALKEI----RLEHEEGAPCTAIREVSLLKDLKH 220
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ + +++LVF+++D DL+ + D ++ NVK ++ L+GL Y H+
Sbjct: 221 ANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQ 280
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
+LHRDLKP LLIN G LK+ DFGLA+A PT+ +++VVT WYR P++L G+ Y
Sbjct: 281 KVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYS 340
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFKL 247
T +DMW VGCI E+ P PG + +QL IF++ GTPTEE WPG+ + ++ +
Sbjct: 341 TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYN- 399
Query: 248 FPAQELRHIFSAA---SEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+P + S A D LL LL NR A++ +F S
Sbjct: 400 YPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLS 448
>BC009852-1|AAH09852.2| 395|Homo sapiens PCTK1 protein protein.
Length = 395
Score = 236 bits (577), Expect = 9e-62
Identities = 119/289 (41%), Positives = 175/289 (60%), Gaps = 8/289 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y K+D LGEG +ATVYK K TD +VA+K+I RLE ++G TA+RE+ LL++L+H
Sbjct: 64 YIKLDKLGEGTYATVYKGKSKLTDNLVALKEI----RLEHEEGAPCTAIREVSLLKDLKH 119
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ + +++LVF+++D DL+ + D ++ NVK ++ L+GL Y H+
Sbjct: 120 ANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQ 179
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
+LHRDLKP LLIN G LK+ DFGLA+A PT+ +++VVT WYR P++L G+ Y
Sbjct: 180 KVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYS 239
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFKL 247
T +DMW VGCI E+ P PG + +QL IF++ GTPTEE WPG+ + ++ +
Sbjct: 240 TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYN- 298
Query: 248 FPAQELRHIFSAA---SEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+P + S A D LL LL NR A++ +F S
Sbjct: 299 YPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLS 347
>BC006190-1|AAH06190.1| 448|Homo sapiens PCTK1 protein protein.
Length = 448
Score = 236 bits (577), Expect = 9e-62
Identities = 119/289 (41%), Positives = 175/289 (60%), Gaps = 8/289 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y K+D LGEG +ATVYK K TD +VA+K+I RLE ++G TA+RE+ LL++L+H
Sbjct: 117 YIKLDKLGEGTYATVYKGKSKLTDNLVALKEI----RLEHEEGAPCTAIREVSLLKDLKH 172
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ + +++LVF+++D DL+ + D ++ NVK ++ L+GL Y H+
Sbjct: 173 ANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQ 232
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
+LHRDLKP LLIN G LK+ DFGLA+A PT+ +++VVT WYR P++L G+ Y
Sbjct: 233 KVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYS 292
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFKL 247
T +DMW VGCI E+ P PG + +QL IF++ GTPTEE WPG+ + ++ +
Sbjct: 293 TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYN- 351
Query: 248 FPAQELRHIFSAA---SEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+P + S A D LL LL NR A++ +F S
Sbjct: 352 YPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLS 400
>BC001048-1|AAH01048.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 236 bits (577), Expect = 9e-62
Identities = 119/289 (41%), Positives = 175/289 (60%), Gaps = 8/289 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y K+D LGEG +ATVYK K TD +VA+K+I RLE ++G TA+RE+ LL++L+H
Sbjct: 165 YIKLDKLGEGTYATVYKGKSKLTDNLVALKEI----RLEHEEGAPCTAIREVSLLKDLKH 220
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ + +++LVF+++D DL+ + D ++ NVK ++ L+GL Y H+
Sbjct: 221 ANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQ 280
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
+LHRDLKP LLIN G LK+ DFGLA+A PT+ +++VVT WYR P++L G+ Y
Sbjct: 281 KVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYS 340
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFKL 247
T +DMW VGCI E+ P PG + +QL IF++ GTPTEE WPG+ + ++ +
Sbjct: 341 TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYN- 399
Query: 248 FPAQELRHIFSAA---SEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+P + S A D LL LL NR A++ +F S
Sbjct: 400 YPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLS 448
>AL096791-1|CAD20055.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 236 bits (577), Expect = 9e-62
Identities = 119/289 (41%), Positives = 175/289 (60%), Gaps = 8/289 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y K+D LGEG +ATVYK K TD +VA+K+I RLE ++G TA+RE+ LL++L+H
Sbjct: 165 YIKLDKLGEGTYATVYKGKSKLTDNLVALKEI----RLEHEEGAPCTAIREVSLLKDLKH 220
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ + +++LVF+++D DL+ + D ++ NVK ++ L+GL Y H+
Sbjct: 221 ANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQ 280
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
+LHRDLKP LLIN G LK+ DFGLA+A PT+ +++VVT WYR P++L G+ Y
Sbjct: 281 KVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYS 340
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFKL 247
T +DMW VGCI E+ P PG + +QL IF++ GTPTEE WPG+ + ++ +
Sbjct: 341 TQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYN- 399
Query: 248 FPAQELRHIFSAA---SEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+P + S A D LL LL NR A++ +F S
Sbjct: 400 YPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLS 448
>Y00272-1|CAA68376.1| 297|Homo sapiens protein ( Human cell cycle
control gene CDC2. ).
Length = 297
Score = 235 bits (574), Expect = 2e-61
Identities = 118/288 (40%), Positives = 176/288 (61%), Gaps = 6/288 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y KI+ +GEG + VYK + T ++VA+KKI++ S ++G+ TA+REI LL+EL+H
Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESE---EEGVPSTAIREISLLKELRH 60
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTI--VLTPANVKAYMIMTLKGLEYLH 125
N++ L DV Q S + L+F+F+ DL+ + + + VK+Y+ L+G+ + H
Sbjct: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
+LHRDLKP LLI+ +G +K+ DFGLA+AFG P R+ TH+VVT WYR+PE+L G+ +
Sbjct: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR 180
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQ- 244
Y T VD+W++G I AEL + P G+S++DQL RIF+ GTP E WP +++L DY
Sbjct: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 240
Query: 245 FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS 292
F + L E+ + LL +L P R AL YF+
Sbjct: 241 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFN 288
>X05360-1|CAA28963.1| 297|Homo sapiens protein ( Human CDC2 gene
involved in cell cycle control. ).
Length = 297
Score = 235 bits (574), Expect = 2e-61
Identities = 118/288 (40%), Positives = 176/288 (61%), Gaps = 6/288 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y KI+ +GEG + VYK + T ++VA+KKI++ S ++G+ TA+REI LL+EL+H
Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESE---EEGVPSTAIREISLLKELRH 60
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTI--VLTPANVKAYMIMTLKGLEYLH 125
N++ L DV Q S + L+F+F+ DL+ + + + VK+Y+ L+G+ + H
Sbjct: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
+LHRDLKP LLI+ +G +K+ DFGLA+AFG P R+ TH+VVT WYR+PE+L G+ +
Sbjct: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR 180
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQ- 244
Y T VD+W++G I AEL + P G+S++DQL RIF+ GTP E WP +++L DY
Sbjct: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 240
Query: 245 FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS 292
F + L E+ + LL +L P R AL YF+
Sbjct: 241 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFN 288
>BT007004-1|AAP35650.1| 297|Homo sapiens cell division cycle 2, G1
to S and G2 to M protein.
Length = 297
Score = 235 bits (574), Expect = 2e-61
Identities = 118/288 (40%), Positives = 176/288 (61%), Gaps = 6/288 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y KI+ +GEG + VYK + T ++VA+KKI++ S ++G+ TA+REI LL+EL+H
Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESE---EEGVPSTAIREISLLKELRH 60
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTI--VLTPANVKAYMIMTLKGLEYLH 125
N++ L DV Q S + L+F+F+ DL+ + + + VK+Y+ L+G+ + H
Sbjct: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
+LHRDLKP LLI+ +G +K+ DFGLA+AFG P R+ TH+VVT WYR+PE+L G+ +
Sbjct: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR 180
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQ- 244
Y T VD+W++G I AEL + P G+S++DQL RIF+ GTP E WP +++L DY
Sbjct: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 240
Query: 245 FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS 292
F + L E+ + LL +L P R AL YF+
Sbjct: 241 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFN 288
>BC014563-1|AAH14563.1| 297|Homo sapiens cell division cycle 2, G1
to S and G2 to M protein.
Length = 297
Score = 235 bits (574), Expect = 2e-61
Identities = 118/288 (40%), Positives = 176/288 (61%), Gaps = 6/288 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y KI+ +GEG + VYK + T ++VA+KKI++ S ++G+ TA+REI LL+EL+H
Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESE---EEGVPSTAIREISLLKELRH 60
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTI--VLTPANVKAYMIMTLKGLEYLH 125
N++ L DV Q S + L+F+F+ DL+ + + + VK+Y+ L+G+ + H
Sbjct: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
+LHRDLKP LLI+ +G +K+ DFGLA+AFG P R+ TH+VVT WYR+PE+L G+ +
Sbjct: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR 180
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQ- 244
Y T VD+W++G I AEL + P G+S++DQL RIF+ GTP E WP +++L DY
Sbjct: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 240
Query: 245 FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS 292
F + L E+ + LL +L P R AL YF+
Sbjct: 241 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFN 288
>AF512554-1|AAM34793.1| 297|Homo sapiens cell division cycle 2, G1
to S and G2 to M protein.
Length = 297
Score = 235 bits (574), Expect = 2e-61
Identities = 118/288 (40%), Positives = 176/288 (61%), Gaps = 6/288 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y KI+ +GEG + VYK + T ++VA+KKI++ S ++G+ TA+REI LL+EL+H
Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESE---EEGVPSTAIREISLLKELRH 60
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTI--VLTPANVKAYMIMTLKGLEYLH 125
N++ L DV Q S + L+F+F+ DL+ + + + VK+Y+ L+G+ + H
Sbjct: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
+LHRDLKP LLI+ +G +K+ DFGLA+AFG P R+ TH+VVT WYR+PE+L G+ +
Sbjct: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR 180
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQ- 244
Y T VD+W++G I AEL + P G+S++DQL RIF+ GTP E WP +++L DY
Sbjct: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 240
Query: 245 FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS 292
F + L E+ + LL +L P R AL YF+
Sbjct: 241 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFN 288
>AY353238-1|AAR13066.1| 504|Homo sapiens PCTAIRE protein kinase 3
isoform b protein.
Length = 504
Score = 233 bits (571), Expect = 5e-61
Identities = 119/288 (41%), Positives = 175/288 (60%), Gaps = 6/288 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y K+D LGEG +ATV+K + T+ +VA+K+I RLE ++G TA+RE+ LL+ L+H
Sbjct: 174 YVKLDKLGEGTYATVFKGRSKLTENLVALKEI----RLEHEEGAPCTAIREVSLLKNLKH 229
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ +++LVF+++D+DL+ + +++ NVK +M L+GL Y H
Sbjct: 230 ANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHR 289
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
ILHRDLKP LLIN G LK+ DFGLA+A PT+ +++VVT WYR P++L G+ +Y
Sbjct: 290 KILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS 349
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDY--VQF 245
T +DMW VGCI E+ P PG + ++L IF++ GTPTEE WPG+ +++ F
Sbjct: 350 TPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSF 409
Query: 246 KLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+ Q L + D I LL SLL +R AL +YF S
Sbjct: 410 PCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRS 457
>AY353237-1|AAR13065.1| 474|Homo sapiens PCTAIRE protein kinase 3
isoform a protein.
Length = 474
Score = 233 bits (571), Expect = 5e-61
Identities = 119/288 (41%), Positives = 175/288 (60%), Gaps = 6/288 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y K+D LGEG +ATV+K + T+ +VA+K+I RLE ++G TA+RE+ LL+ L+H
Sbjct: 144 YVKLDKLGEGTYATVFKGRSKLTENLVALKEI----RLEHEEGAPCTAIREVSLLKNLKH 199
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ +++LVF+++D+DL+ + +++ NVK +M L+GL Y H
Sbjct: 200 ANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHR 259
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
ILHRDLKP LLIN G LK+ DFGLA+A PT+ +++VVT WYR P++L G+ +Y
Sbjct: 260 KILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS 319
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDY--VQF 245
T +DMW VGCI E+ P PG + ++L IF++ GTPTEE WPG+ +++ F
Sbjct: 320 TPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSF 379
Query: 246 KLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+ Q L + D I LL SLL +R AL +YF S
Sbjct: 380 PCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRS 427
>AL357131-4|CAH72012.1| 472|Homo sapiens PCTAIRE protein kinase 3
protein.
Length = 472
Score = 233 bits (571), Expect = 5e-61
Identities = 119/288 (41%), Positives = 175/288 (60%), Gaps = 6/288 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y K+D LGEG +ATV+K + T+ +VA+K+I RLE ++G TA+RE+ LL+ L+H
Sbjct: 142 YVKLDKLGEGTYATVFKGRSKLTENLVALKEI----RLEHEEGAPCTAIREVSLLKNLKH 197
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ +++LVF+++D+DL+ + +++ NVK +M L+GL Y H
Sbjct: 198 ANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHR 257
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
ILHRDLKP LLIN G LK+ DFGLA+A PT+ +++VVT WYR P++L G+ +Y
Sbjct: 258 KILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS 317
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDY--VQF 245
T +DMW VGCI E+ P PG + ++L IF++ GTPTEE WPG+ +++ F
Sbjct: 318 TPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSF 377
Query: 246 KLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+ Q L + D I LL SLL +R AL +YF S
Sbjct: 378 PCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRS 425
>AB209307-1|BAD92544.1| 436|Homo sapiens PCTAIRE protein kinase 3
isoform b variant protein.
Length = 436
Score = 233 bits (571), Expect = 5e-61
Identities = 119/288 (41%), Positives = 175/288 (60%), Gaps = 6/288 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y K+D LGEG +ATV+K + T+ +VA+K+I RLE ++G TA+RE+ LL+ L+H
Sbjct: 106 YVKLDKLGEGTYATVFKGRSKLTENLVALKEI----RLEHEEGAPCTAIREVSLLKNLKH 161
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ +++LVF+++D+DL+ + +++ NVK +M L+GL Y H
Sbjct: 162 ANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHR 221
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
ILHRDLKP LLIN G LK+ DFGLA+A PT+ +++VVT WYR P++L G+ +Y
Sbjct: 222 KILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS 281
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDY--VQF 245
T +DMW VGCI E+ P PG + ++L IF++ GTPTEE WPG+ +++ F
Sbjct: 282 TPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSF 341
Query: 246 KLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+ Q L + D I LL SLL +R AL +YF S
Sbjct: 342 PCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRS 389
>BC033005-1|AAH33005.1| 523|Homo sapiens PCTAIRE protein kinase 2
protein.
Length = 523
Score = 231 bits (566), Expect = 2e-60
Identities = 119/318 (37%), Positives = 193/318 (60%), Gaps = 14/318 (4%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y K++ LGEG +ATVYK + T+ +VA+K+I RLE ++G TA+RE+ LL++L+H
Sbjct: 192 YIKLEKLGEGTYATVYKGRSKLTENLVALKEI----RLEHEEGAPCTAIREVSLLKDLKH 247
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ +++LVF+++D DL+ + D +++ NVK ++ L+GL Y H+
Sbjct: 248 ANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRR 307
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
+LHRDLKP LLIN +G LK+ DFGLA+A PT+ +++VVT WYR P++L G+ +Y
Sbjct: 308 KVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYS 367
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQF-- 245
T +DMW VGCI E+ P PG + D+L IF++ GTP++E WPG+ + ++ +
Sbjct: 368 TQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNYNF 427
Query: 246 -KLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKL- 303
K P + H SE I L+ L R +A++ YF S+GP++
Sbjct: 428 PKYKPQPLINHAPRLDSEG-IELITKFLQYESKKRVSAEEAMKHVYFR-----SLGPRIH 481
Query: 304 PMPSNISKLEVEKPSLKR 321
+P ++S +++ L++
Sbjct: 482 ALPESVSIFSLKEIQLQK 499
>BT007299-1|AAP35963.1| 472|Homo sapiens PCTAIRE-motif protein
kinase 3 protein.
Length = 472
Score = 231 bits (565), Expect = 3e-60
Identities = 118/288 (40%), Positives = 174/288 (60%), Gaps = 6/288 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y K+D LGEG +ATV+K + + +VA+K+I RLE ++G TA+RE+ LL+ L+H
Sbjct: 142 YVKLDKLGEGTYATVFKGRSKLMENLVALKEI----RLEHEEGAPCTAIREVSLLKNLKH 197
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ +++LVF+++D+DL+ + +++ NVK +M L+GL Y H
Sbjct: 198 ANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHR 257
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
ILHRDLKP LLIN G LK+ DFGLA+A PT+ +++VVT WYR P++L G+ +Y
Sbjct: 258 KILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS 317
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDY--VQF 245
T +DMW VGCI E+ P PG + ++L IF++ GTPTEE WPG+ +++ F
Sbjct: 318 TPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSF 377
Query: 246 KLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+ Q L + D I LL SLL +R AL +YF S
Sbjct: 378 PCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRS 425
>BC011526-1|AAH11526.1| 472|Homo sapiens PCTAIRE protein kinase 3
protein.
Length = 472
Score = 231 bits (565), Expect = 3e-60
Identities = 118/288 (40%), Positives = 174/288 (60%), Gaps = 6/288 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y K+D LGEG +ATV+K + + +VA+K+I RLE ++G TA+RE+ LL+ L+H
Sbjct: 142 YVKLDKLGEGTYATVFKGRSKLMENLVALKEI----RLEHEEGAPCTAIREVSLLKNLKH 197
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ +++LVF+++D+DL+ + +++ NVK +M L+GL Y H
Sbjct: 198 ANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHR 257
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
ILHRDLKP LLIN G LK+ DFGLA+A PT+ +++VVT WYR P++L G+ +Y
Sbjct: 258 KILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS 317
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDY--VQF 245
T +DMW VGCI E+ P PG + ++L IF++ GTPTEE WPG+ +++ F
Sbjct: 318 TPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSF 377
Query: 246 KLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+ Q L + D I LL SLL +R AL +YF S
Sbjct: 378 PCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRS 425
>X66362-1|CAA47005.1| 380|Homo sapiens serine/threonine protein
kinase protein.
Length = 380
Score = 230 bits (563), Expect = 5e-60
Identities = 118/288 (40%), Positives = 174/288 (60%), Gaps = 6/288 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y K+D LGEG +ATV+K + T+ +VA+K+I RLE ++G TA+RE+ LL+ L+H
Sbjct: 50 YVKLDKLGEGTYATVFKGRSKLTENLVALKEI----RLEHEEGAPCTAIREVSLLKNLKH 105
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ +++LVF+++D+DL+ + +++ NVK +M L+GL Y H
Sbjct: 106 ANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHTR 165
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
ILHRDLKP LLIN G LK+ DFGLA+A PT+ +++VVT WYR P++L G+ +Y
Sbjct: 166 KILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS 225
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDY--VQF 245
T + MW VGCI E+ P PG + ++L IF++ GTPTEE WPG+ +++ F
Sbjct: 226 TPIAMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSF 285
Query: 246 KLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+ Q L + D I LL SLL +R AL +YF S
Sbjct: 286 PCYLPQPLINHAPRLDTDGIHLLSSLLVYESKSRMSAEAALSHSYFRS 333
>X66360-1|CAA47004.1| 523|Homo sapiens serine/threonine protein
kinase protein.
Length = 523
Score = 230 bits (563), Expect = 5e-60
Identities = 119/318 (37%), Positives = 193/318 (60%), Gaps = 14/318 (4%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y K++ LGEG +ATVYK + T+ +VA+K+I RLE ++G TA+RE+ LL++L+H
Sbjct: 192 YIKLEKLGEGTYATVYKGRSKLTENLVALKEI----RLEHEEGAPCTAIREVSLLKDLKH 247
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ +++LVF+++D DL+ + D +++ NVK ++ L+GL Y H+
Sbjct: 248 ANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRR 307
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
+LHRDLKP LLIN +G LK+ DFGLA+A PT+ +++VVT WYR P++L G+ +Y
Sbjct: 308 KVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYL 367
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQF-- 245
T +DMW VGCI E+ P PG + D+L IF++ GTP++E WPG+ + ++ +
Sbjct: 368 TQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNYNF 427
Query: 246 -KLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKL- 303
K P + H SE I L+ L R +A++ YF S+GP++
Sbjct: 428 PKYKPEPLINHAPRLDSEG-IELIRKFLQYESKKRVSAEEAMKHVYFR-----SLGPRIH 481
Query: 304 PMPSNISKLEVEKPSLKR 321
+P ++S +++ L++
Sbjct: 482 ALPESVSIFSLKEIQLQK 499
>L25676-1|AAA35668.1| 372|Homo sapiens CDC2-related kinase protein.
Length = 372
Score = 213 bits (520), Expect = 7e-55
Identities = 122/309 (39%), Positives = 180/309 (58%), Gaps = 21/309 (6%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
+YEK+ +G+G F V+KA+ KT + VA+KK+ + + E G TALREIK+LQ L+
Sbjct: 18 KYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKE---GFPITALREIKILQLLK 74
Query: 67 HINLIGLLDVFGQKSN--------VSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTL 118
H N++ L+++ K++ + LVFDF + DL ++ + + T + +K M M L
Sbjct: 75 HENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLL 134
Query: 119 KGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFG-----SPTRINTHQVVTRW 173
GL Y+H+N ILHRD+K +LI R+G+LK+ DFGLA+AF P R T++VVT W
Sbjct: 135 NGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRY-TNRVVTLW 193
Query: 174 YRAPELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENW 233
YR PELL G R YG +D+W GCI+AE+ R P + G ++ QL+ I Q+ G+ T E W
Sbjct: 194 YRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVW 253
Query: 234 PGMKTLTDYVQFKLFPAQ--ELRHIFSAASED--LIFLLESLLALYPPNRCDCTQALQMA 289
P + Y + +L Q +++ A D + L++ LL L P R D AL
Sbjct: 254 PNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHD 313
Query: 290 YFSSKPAPS 298
+F S P PS
Sbjct: 314 FFWSDPMPS 322
>BC001968-1|AAH01968.1| 372|Homo sapiens cyclin-dependent kinase 9
(CDC2-related kinase) protein.
Length = 372
Score = 213 bits (520), Expect = 7e-55
Identities = 122/309 (39%), Positives = 180/309 (58%), Gaps = 21/309 (6%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
+YEK+ +G+G F V+KA+ KT + VA+KK+ + + E G TALREIK+LQ L+
Sbjct: 18 KYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKE---GFPITALREIKILQLLK 74
Query: 67 HINLIGLLDVFGQKSN--------VSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTL 118
H N++ L+++ K++ + LVFDF + DL ++ + + T + +K M M L
Sbjct: 75 HENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLL 134
Query: 119 KGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFG-----SPTRINTHQVVTRW 173
GL Y+H+N ILHRD+K +LI R+G+LK+ DFGLA+AF P R T++VVT W
Sbjct: 135 NGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRY-TNRVVTLW 193
Query: 174 YRAPELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENW 233
YR PELL G R YG +D+W GCI+AE+ R P + G ++ QL+ I Q+ G+ T E W
Sbjct: 194 YRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVW 253
Query: 234 PGMKTLTDYVQFKLFPAQ--ELRHIFSAASED--LIFLLESLLALYPPNRCDCTQALQMA 289
P + Y + +L Q +++ A D + L++ LL L P R D AL
Sbjct: 254 PNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHD 313
Query: 290 YFSSKPAPS 298
+F S P PS
Sbjct: 314 FFWSDPMPS 322
>AL162586-9|CAI39768.1| 372|Homo sapiens cyclin-dependent kinase 9
(CDC2-related kinase) protein.
Length = 372
Score = 213 bits (520), Expect = 7e-55
Identities = 122/309 (39%), Positives = 180/309 (58%), Gaps = 21/309 (6%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
+YEK+ +G+G F V+KA+ KT + VA+KK+ + + E G TALREIK+LQ L+
Sbjct: 18 KYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKE---GFPITALREIKILQLLK 74
Query: 67 HINLIGLLDVFGQKSN--------VSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTL 118
H N++ L+++ K++ + LVFDF + DL ++ + + T + +K M M L
Sbjct: 75 HENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLL 134
Query: 119 KGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFG-----SPTRINTHQVVTRW 173
GL Y+H+N ILHRD+K +LI R+G+LK+ DFGLA+AF P R T++VVT W
Sbjct: 135 NGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRY-TNRVVTLW 193
Query: 174 YRAPELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENW 233
YR PELL G R YG +D+W GCI+AE+ R P + G ++ QL+ I Q+ G+ T E W
Sbjct: 194 YRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVW 253
Query: 234 PGMKTLTDYVQFKLFPAQ--ELRHIFSAASED--LIFLLESLLALYPPNRCDCTQALQMA 289
P + Y + +L Q +++ A D + L++ LL L P R D AL
Sbjct: 254 PNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHD 313
Query: 290 YFSSKPAPS 298
+F S P PS
Sbjct: 314 FFWSDPMPS 322
>AF517840-1|AAM54039.1| 372|Homo sapiens cyclin-dependent kinase 9
(CDC2-related kinase) protein.
Length = 372
Score = 213 bits (520), Expect = 7e-55
Identities = 122/309 (39%), Positives = 180/309 (58%), Gaps = 21/309 (6%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
+YEK+ +G+G F V+KA+ KT + VA+KK+ + + E G TALREIK+LQ L+
Sbjct: 18 KYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKE---GFPITALREIKILQLLK 74
Query: 67 HINLIGLLDVFGQKSN--------VSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTL 118
H N++ L+++ K++ + LVFDF + DL ++ + + T + +K M M L
Sbjct: 75 HENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLL 134
Query: 119 KGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFG-----SPTRINTHQVVTRW 173
GL Y+H+N ILHRD+K +LI R+G+LK+ DFGLA+AF P R T++VVT W
Sbjct: 135 NGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRY-TNRVVTLW 193
Query: 174 YRAPELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENW 233
YR PELL G R YG +D+W GCI+AE+ R P + G ++ QL+ I Q+ G+ T E W
Sbjct: 194 YRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVW 253
Query: 234 PGMKTLTDYVQFKLFPAQ--ELRHIFSAASED--LIFLLESLLALYPPNRCDCTQALQMA 289
P + Y + +L Q +++ A D + L++ LL L P R D AL
Sbjct: 254 PNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHD 313
Query: 290 YFSSKPAPS 298
+F S P PS
Sbjct: 314 FFWSDPMPS 322
>BC038807-1|AAH38807.1| 349|Homo sapiens ALS2CR7 protein protein.
Length = 349
Score = 212 bits (518), Expect = 1e-54
Identities = 112/294 (38%), Positives = 171/294 (58%), Gaps = 9/294 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y ++ LGEG +ATVYK ++VA+K I + A++G+ TA+RE LL+ L+H
Sbjct: 52 YLNLEKLGEGSYATVYKGISRINGQLVALKVIS----MNAEEGVPFTAIREASLLKGLKH 107
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ K ++ VF++M TDL + + L P NV+ +M L+GL Y+H
Sbjct: 108 ANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQ 167
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
+LHRDLKP LLI+ G LK+ DFGLA+A P++ + +VVT WYR P+ L GA +Y
Sbjct: 168 HVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYS 227
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESD-LDQLSRIFQVFGTPTEENWPGMKTLTDY--VQ 244
+ +D+W GCI E+ P PG S+ L+QL +I++V G PTE+ WPG+ L +Y
Sbjct: 228 SELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEW 287
Query: 245 FKLFPAQELRHIFSAASE--DLIFLLESLLALYPPNRCDCTQALQMAYFSSKPA 296
F L + L +++ + L +L +P +R +AL YFS+ P+
Sbjct: 288 FPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSALPS 341
>AB053308-1|BAB69017.1| 384|Homo sapiens ALS2CR7 protein.
Length = 384
Score = 212 bits (518), Expect = 1e-54
Identities = 112/294 (38%), Positives = 171/294 (58%), Gaps = 9/294 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y ++ LGEG +ATVYK ++VA+K I + A++G+ TA+RE LL+ L+H
Sbjct: 52 YLNLEKLGEGSYATVYKGISRINGQLVALKVIS----MNAEEGVPFTAIREASLLKGLKH 107
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ K ++ VF++M TDL + + L P NV+ +M L+GL Y+H
Sbjct: 108 ANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQ 167
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
+LHRDLKP LLI+ G LK+ DFGLA+A P++ + +VVT WYR P+ L GA +Y
Sbjct: 168 HVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYS 227
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESD-LDQLSRIFQVFGTPTEENWPGMKTLTDY--VQ 244
+ +D+W GCI E+ P PG S+ L+QL +I++V G PTE+ WPG+ L +Y
Sbjct: 228 SELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEW 287
Query: 245 FKLFPAQELRHIFSAASE--DLIFLLESLLALYPPNRCDCTQALQMAYFSSKPA 296
F L + L +++ + L +L +P +R +AL YFS+ P+
Sbjct: 288 FPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSALPS 341
>X80230-1|CAA56516.1| 372|Homo sapiens serine/threonine protein
kinase protein.
Length = 372
Score = 210 bits (514), Expect = 4e-54
Identities = 121/309 (39%), Positives = 179/309 (57%), Gaps = 21/309 (6%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
+YEK+ +G+G F V+KA+ KT + VA+KK+ + + E G TALREIK+LQ L+
Sbjct: 18 KYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKE---GFPITALREIKILQLLK 74
Query: 67 HINLIGLLDVFGQKSN--------VSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTL 118
H N++ L+++ K++ + LVFDF + DL ++ + + T + +K M M L
Sbjct: 75 HENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLL 134
Query: 119 KGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFG-----SPTRINTHQVVTRW 173
GL Y+H+N ILHRD+K +LI R+G+LK+ DFGLA+AF P R T++VVT W
Sbjct: 135 NGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRY-TNRVVTLW 193
Query: 174 YRAPELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENW 233
YR PELL G R YG +D+W GCI+AE+ R P + ++ QL+ I Q+ G+ T E W
Sbjct: 194 YRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQANTEQHQLALISQLCGSITPEVW 253
Query: 234 PGMKTLTDYVQFKLFPAQ--ELRHIFSAASED--LIFLLESLLALYPPNRCDCTQALQMA 289
P + Y + +L Q +++ A D + L++ LL L P R D AL
Sbjct: 254 PNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHD 313
Query: 290 YFSSKPAPS 298
+F S P PS
Sbjct: 314 FFWSDPMPS 322
>AF255306-1|AAF72183.1| 372|Homo sapiens protein kinase CDK9
protein.
Length = 372
Score = 210 bits (514), Expect = 4e-54
Identities = 121/309 (39%), Positives = 179/309 (57%), Gaps = 21/309 (6%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
+YEK+ +G+G F V+KA+ KT + VA+KK+ + + E G TALREIK+LQ L+
Sbjct: 18 KYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKE---GFPITALREIKILQLLK 74
Query: 67 HINLIGLLDVFGQKSN--------VSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTL 118
H N++ L+++ K++ + LVFDF + DL ++ + + T + +K M M L
Sbjct: 75 HENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLL 134
Query: 119 KGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFG-----SPTRINTHQVVTRW 173
GL Y+H+N ILHRD+K +LI R+G+LK+ DFGLA+AF P R T++VVT W
Sbjct: 135 NGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRY-TNRVVTLW 193
Query: 174 YRAPELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENW 233
YR PELL G R YG +D+W GCI+AE+ R P + ++ QL+ I Q+ G+ T E W
Sbjct: 194 YRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQANTEQHQLALISQLCGSITPEVW 253
Query: 234 PGMKTLTDYVQFKLFPAQ--ELRHIFSAASED--LIFLLESLLALYPPNRCDCTQALQMA 289
P + Y + +L Q +++ A D + L++ LL L P R D AL
Sbjct: 254 PNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHD 313
Query: 290 YFSSKPAPS 298
+F S P PS
Sbjct: 314 FFWSDPMPS 322
>BT019903-1|AAV38706.1| 372|Homo sapiens cyclin-dependent kinase 9
(CDC2-related kinase) protein.
Length = 372
Score = 210 bits (513), Expect = 5e-54
Identities = 121/309 (39%), Positives = 179/309 (57%), Gaps = 21/309 (6%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
+YEK+ +G+G F V+KA+ KT + VA+KK+ + + E G TALREIK+LQ L+
Sbjct: 18 KYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKE---GFPITALREIKILQLLK 74
Query: 67 HINLIGLLDVFGQKSN--------VSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTL 118
H N++ L+++ K++ + LVFDF + DL ++ + + T + +K M M L
Sbjct: 75 HENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLL 134
Query: 119 KGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFG-----SPTRINTHQVVTRW 173
GL Y+H+N ILHRD+K +LI R+G+ K+ DFGLA+AF P R T++VVT W
Sbjct: 135 NGLYYIHRNKILHRDMKAANVLITRDGVPKLADFGLARAFSLAKNSQPNRY-TNRVVTLW 193
Query: 174 YRAPELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENW 233
YR PELL G R YG +D+W GCI+AE+ R P + G ++ QL+ I Q+ G+ T E W
Sbjct: 194 YRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVW 253
Query: 234 PGMKTLTDYVQFKLFPAQ--ELRHIFSAASED--LIFLLESLLALYPPNRCDCTQALQMA 289
P + Y + +L Q +++ A D + L++ LL L P R D AL
Sbjct: 254 PNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHD 313
Query: 290 YFSSKPAPS 298
+F S P PS
Sbjct: 314 FFWSDPMPS 322
>BC107750-1|AAI07751.1| 225|Homo sapiens CDC2 protein protein.
Length = 225
Score = 208 bits (507), Expect = 3e-53
Identities = 99/223 (44%), Positives = 149/223 (66%), Gaps = 5/223 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y KI+ +GEG + VYK + T ++VA+KKI++ S ++G+ TA+REI LL+EL+H
Sbjct: 4 YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESE---EEGVPSTAIREISLLKELRH 60
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTI--VLTPANVKAYMIMTLKGLEYLH 125
N++ L DV Q S + L+F+F+ DL+ + + + VK+Y+ L+G+ + H
Sbjct: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
Query: 126 QNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQ 185
+LHRDLKP LLI+ +G +K+ DFGLA+AFG P R+ TH+VVT WYR+PE+L G+ +
Sbjct: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR 180
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTP 228
Y T VD+W++G I AEL + P G+S++DQL RIF+ F P
Sbjct: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRNFCFP 223
>AC007242-1|AAX93182.1| 301|Homo sapiens unknown protein.
Length = 301
Score = 205 bits (501), Expect = 2e-52
Identities = 99/236 (41%), Positives = 147/236 (62%), Gaps = 5/236 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y ++ LGEG +ATVYK ++VA+K I + A++G+ TA+RE LL+ L+H
Sbjct: 52 YLNLEKLGEGSYATVYKGISRINGQLVALKVIS----MNAEEGVPFTAIREASLLKGLKH 107
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ K ++ VF++M TDL + + L P NV+ +M L+GL Y+H
Sbjct: 108 ANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQ 167
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
+LHRDLKP LLI+ G LK+ DFGLA+A P++ + +VVT WYR P+ L GA +Y
Sbjct: 168 HVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYS 227
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESD-LDQLSRIFQVFGTPTEENWPGMKTLTDY 242
+ +D+W GCI E+ P PG S+ L+QL +I++V G PTE+ WPG+ L +Y
Sbjct: 228 SELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNY 283
>BC025301-1|AAH25301.1| 272|Homo sapiens CDK10 protein protein.
Length = 272
Score = 205 bits (500), Expect = 2e-52
Identities = 107/252 (42%), Positives = 149/252 (59%), Gaps = 4/252 (1%)
Query: 48 QDGINRTALREIKLLQELQHINLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVL 105
+DGI ++LREI LL L+H N++ L +V ++ LV + + DL ++++
Sbjct: 5 KDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPF 64
Query: 106 TPANVKAYMIMTLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRIN 165
+ A VK ++ L+GL+YLH+N+I+HRDLK + LL+ +G +K DFGLA+A+G P +
Sbjct: 65 SEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPM 124
Query: 166 THQVVTRWYRAPELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVF 225
T +VVT WYRAPELL G T +DMWAVGCILAELL P LPG S++ Q+ I Q+
Sbjct: 125 TPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLL 184
Query: 226 GTPTEENWPGMKTLTDYVQFKL--FPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCT 283
GTP+E WPG L Q+ L P L+H F SE + LL L P R
Sbjct: 185 GTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAG 244
Query: 284 QALQMAYFSSKP 295
L+ +YF KP
Sbjct: 245 DCLESSYFKEKP 256
>BC017342-1|AAH17342.1| 283|Homo sapiens CDK10 protein protein.
Length = 283
Score = 199 bits (485), Expect = 1e-50
Identities = 109/261 (41%), Positives = 153/261 (58%), Gaps = 10/261 (3%)
Query: 48 QDGINRTALREIKLLQELQHINLIGLLDVF--GQKSNVSLVFDFMDTDLEIIIKDNTIVL 105
+DGI ++LREI LL L+H N++ L +V ++ LV + + DL ++++
Sbjct: 5 KDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPF 64
Query: 106 TPANVKAYMIMTLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRIN 165
+ A VK ++ L+GL+YLH+N+I+HRDLK + LL+ +G +K DFGLA+A+G P +
Sbjct: 65 SEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPM 124
Query: 166 THQVVTRWYRAPELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVF 225
T +VVT WYRAPELL G T +DMWAVGCILAELL P LPG S++ Q+ I Q+
Sbjct: 125 TPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLL 184
Query: 226 GTPTEENWPGMKTLTDYVQFKL--FPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCT 283
GTP+E WPG L Q+ L P L+H F SE + LL L+ DC
Sbjct: 185 GTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLH---FLFMATAGDC- 240
Query: 284 QALQMAYFSSKPAPSVGPKLP 304
L+ +YF KP P +P
Sbjct: 241 --LESSYFKEKPLPCEPELMP 259
>AY847283-1|AAW31760.1| 379|Homo sapiens cyclin-dependent
kinase-like 4 protein.
Length = 379
Score = 193 bits (470), Expect = 9e-49
Identities = 104/292 (35%), Positives = 169/292 (57%), Gaps = 11/292 (3%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDG--INRTALREIKLLQE 64
+YEK+ GEG + V+K ++ + ++VAVKK +E++D + + ALREI++L++
Sbjct: 3 KYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKF-----VESEDDPVVKKIALREIRMLKQ 57
Query: 65 LQHINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYL 124
L+H NL+ L++VF +K + LVF++ D L ++ N + +K+ + TL+ L +
Sbjct: 58 LKHPNLVNLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFC 117
Query: 125 HQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGAR 184
H + +HRD+KP +LI ++GI+KI DFG A+ P T V TRWYRAPELL G
Sbjct: 118 HIHNCIHRDIKPENILITKQGIIKICDFGFAQIL-IPGDAYTDYVATRWYRAPELLVGDT 176
Query: 185 QYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQ 244
QYG+ VD+WA+GC+ AELL P PG+SD+DQL I + G + K+ +
Sbjct: 177 QYGSSVDIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKSNGFFHG 236
Query: 245 FKLFPAQELRHI---FSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+ +++ + FS + ++ L + P +R C+Q L+ +YF S
Sbjct: 237 ISIPEPEDMETLEEKFSDVHPVALNFMKGCLKMNPDDRLTCSQLLESSYFDS 288
>AY845084-1|AAW30008.1| 315|Homo sapiens cyclin-dependent
kinase-like 4 protein.
Length = 315
Score = 193 bits (470), Expect = 9e-49
Identities = 104/292 (35%), Positives = 169/292 (57%), Gaps = 11/292 (3%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDG--INRTALREIKLLQE 64
+YEK+ GEG + V+K ++ + ++VAVKK +E++D + + ALREI++L++
Sbjct: 3 KYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKF-----VESEDDPVVKKIALREIRMLKQ 57
Query: 65 LQHINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYL 124
L+H NL+ L++VF +K + LVF++ D L ++ N + +K+ + TL+ L +
Sbjct: 58 LKHPNLVNLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFC 117
Query: 125 HQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGAR 184
H + +HRD+KP +LI ++GI+KI DFG A+ P T V TRWYRAPELL G
Sbjct: 118 HIHNCIHRDIKPENILITKQGIIKICDFGFAQIL-IPGDAYTDYVATRWYRAPELLVGDT 176
Query: 185 QYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQ 244
QYG+ VD+WA+GC+ AELL P PG+SD+DQL I + G + K+ +
Sbjct: 177 QYGSSVDIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKSNGFFHG 236
Query: 245 FKLFPAQELRHI---FSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+ +++ + FS + ++ L + P +R C+Q L+ +YF S
Sbjct: 237 ISIPEPEDMETLEEKFSDVHPVALNFMKGCLKMNPDDRLTCSQLLESSYFDS 288
>AY679523-1|AAT74623.1| 1512|Homo sapiens cell division cycle 2-like 5
(cholinesterase-related cell division controller)
protein.
Length = 1512
Score = 193 bits (470), Expect = 9e-49
Identities = 107/331 (32%), Positives = 185/331 (55%), Gaps = 17/331 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
+++ I +GEG + VYKA+D T ++VA+KK+++ + E G TA+REIK+L++L
Sbjct: 704 KFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKE---GFPITAIREIKILRQLT 760
Query: 67 HINLIGLLDVFGQKSNVS----------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIM 116
H ++I + ++ K + LVF++MD DL +++ + ++K++M
Sbjct: 761 HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQ 820
Query: 117 TLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSP-TRINTHQVVTRWYR 175
++GL+Y H+ LHRD+K + +L+N G +K+ DFGLA+ + S +R T++V+T WYR
Sbjct: 821 LMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYR 880
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
PELL G +Y +D+W+ GCIL EL + P +L QL I ++ G+P WP
Sbjct: 881 PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPD 940
Query: 236 MKTLTDY--VQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+ L + ++ K ++LR F + L + +LAL P RC QALQ +
Sbjct: 941 VIKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRD 1000
Query: 294 -KPAPSVGPKLPMPSNISKLEVEKPSLKRKL 323
+P+ P LP+ + +L +K ++++
Sbjct: 1001 VEPSKMPPPDLPLWQDCHELWSKKRRRQKQM 1031
>AJ297710-1|CAC10401.1| 1452|Homo sapiens CDC2L5 protein kinase
protein.
Length = 1452
Score = 193 bits (470), Expect = 9e-49
Identities = 107/331 (32%), Positives = 185/331 (55%), Gaps = 17/331 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
+++ I +GEG + VYKA+D T ++VA+KK+++ + E G TA+REIK+L++L
Sbjct: 704 KFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKE---GFPITAIREIKILRQLT 760
Query: 67 HINLIGLLDVFGQKSNVS----------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIM 116
H ++I + ++ K + LVF++MD DL +++ + ++K++M
Sbjct: 761 HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQ 820
Query: 117 TLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSP-TRINTHQVVTRWYR 175
++GL+Y H+ LHRD+K + +L+N G +K+ DFGLA+ + S +R T++V+T WYR
Sbjct: 821 LMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYR 880
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
PELL G +Y +D+W+ GCIL EL + P +L QL I ++ G+P WP
Sbjct: 881 PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPD 940
Query: 236 MKTLTDY--VQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+ L + ++ K ++LR F + L + +LAL P RC QALQ +
Sbjct: 941 VIKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRD 1000
Query: 294 -KPAPSVGPKLPMPSNISKLEVEKPSLKRKL 323
+P+ P LP+ + +L +K ++++
Sbjct: 1001 VEPSKMPPPDLPLWQDCHELWSKKRRRQKQM 1031
>AJ297709-1|CAC10400.1| 1512|Homo sapiens CDC2L5 protein kinase
protein.
Length = 1512
Score = 193 bits (470), Expect = 9e-49
Identities = 107/331 (32%), Positives = 185/331 (55%), Gaps = 17/331 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
+++ I +GEG + VYKA+D T ++VA+KK+++ + E G TA+REIK+L++L
Sbjct: 704 KFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKE---GFPITAIREIKILRQLT 760
Query: 67 HINLIGLLDVFGQKSNVS----------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIM 116
H ++I + ++ K + LVF++MD DL +++ + ++K++M
Sbjct: 761 HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQ 820
Query: 117 TLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSP-TRINTHQVVTRWYR 175
++GL+Y H+ LHRD+K + +L+N G +K+ DFGLA+ + S +R T++V+T WYR
Sbjct: 821 LMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYR 880
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
PELL G +Y +D+W+ GCIL EL + P +L QL I ++ G+P WP
Sbjct: 881 PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPD 940
Query: 236 MKTLTDY--VQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+ L + ++ K ++LR F + L + +LAL P RC QALQ +
Sbjct: 941 VIKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRD 1000
Query: 294 -KPAPSVGPKLPMPSNISKLEVEKPSLKRKL 323
+P+ P LP+ + +L +K ++++
Sbjct: 1001 VEPSKMPPPDLPLWQDCHELWSKKRRRQKQM 1031
>X66358-1|CAA47002.1| 358|Homo sapiens serine/threonine protein
kinase protein.
Length = 358
Score = 191 bits (466), Expect = 3e-48
Identities = 106/292 (36%), Positives = 164/292 (56%), Gaps = 10/292 (3%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDG--INRTALREIKLLQE 64
+YEKI +GEG + V+K ++ T +IVA+KK LE++D I + ALREI++L++
Sbjct: 4 KYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKF-----LESEDDPVIKKIALREIRMLKQ 58
Query: 65 LQHINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYL 124
L+H NL+ LL+VF +K + LVF++ D + + + VK+ TL+ + +
Sbjct: 59 LKHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFC 118
Query: 125 HQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGAR 184
H++ +HRD+KP +LI + ++K+ DFG A+ P+ T V TRWYR+PELL G
Sbjct: 119 HKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDT 178
Query: 185 QYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQ 244
QYG VD+WA+GC+ AELL VP PG+SD+DQL I + G + T +
Sbjct: 179 QYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSG 238
Query: 245 FKLFPAQELRHI---FSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
K+ +++ + F S + LL+ L + P R C Q L YF +
Sbjct: 239 VKIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTERLTCEQLLHHPYFEN 290
>BC104977-1|AAI04978.1| 358|Homo sapiens cyclin-dependent
kinase-like 1 (CDC2-related kinase) protein.
Length = 358
Score = 191 bits (466), Expect = 3e-48
Identities = 106/292 (36%), Positives = 164/292 (56%), Gaps = 10/292 (3%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDG--INRTALREIKLLQE 64
+YEKI +GEG + V+K ++ T +IVA+KK LE++D I + ALREI++L++
Sbjct: 4 KYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKF-----LESEDDPVIKKIALREIRMLKQ 58
Query: 65 LQHINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYL 124
L+H NL+ LL+VF +K + LVF++ D + + + VK+ TL+ + +
Sbjct: 59 LKHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFC 118
Query: 125 HQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGAR 184
H++ +HRD+KP +LI + ++K+ DFG A+ P+ T V TRWYR+PELL G
Sbjct: 119 HKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDT 178
Query: 185 QYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQ 244
QYG VD+WA+GC+ AELL VP PG+SD+DQL I + G + T +
Sbjct: 179 QYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSG 238
Query: 245 FKLFPAQELRHI---FSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
K+ +++ + F S + LL+ L + P R C Q L YF +
Sbjct: 239 VKIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFEN 290
>AY525548-1|AAS00095.1| 358|Homo sapiens cyclin-dependent
kinase-like 1 (CDC2-related kinase) protein.
Length = 358
Score = 191 bits (466), Expect = 3e-48
Identities = 106/292 (36%), Positives = 164/292 (56%), Gaps = 10/292 (3%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDG--INRTALREIKLLQE 64
+YEKI +GEG + V+K ++ T +IVA+KK LE++D I + ALREI++L++
Sbjct: 4 KYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKF-----LESEDDPVIKKIALREIRMLKQ 58
Query: 65 LQHINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYL 124
L+H NL+ LL+VF +K + LVF++ D + + + VK+ TL+ + +
Sbjct: 59 LKHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFC 118
Query: 125 HQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGAR 184
H++ +HRD+KP +LI + ++K+ DFG A+ P+ T V TRWYR+PELL G
Sbjct: 119 HKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDT 178
Query: 185 QYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQ 244
QYG VD+WA+GC+ AELL VP PG+SD+DQL I + G + T +
Sbjct: 179 QYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSG 238
Query: 245 FKLFPAQELRHI---FSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
K+ +++ + F S + LL+ L + P R C Q L YF +
Sbjct: 239 VKIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTERLTCEQLLHHPYFEN 290
>AB020711-1|BAA74927.2| 1535|Homo sapiens KIAA0904 protein protein.
Length = 1535
Score = 190 bits (464), Expect = 5e-48
Identities = 112/333 (33%), Positives = 184/333 (55%), Gaps = 23/333 (6%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
+++ I +GEG + VYKAKD T ++VA+KK+++ + E G TA+REIK+L++L
Sbjct: 780 KFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKE---GFPITAIREIKILRQLI 836
Query: 67 HINLIGLLDVFGQKSNVS----------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIM 116
H +++ + ++ K + LVF++MD DL +++ + + ++K++M
Sbjct: 837 HRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQ 896
Query: 117 TLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGS-PTRINTHQVVTRWYR 175
++GLEY H+ LHRD+K + +L+N G +K+ DFGLA+ + S +R T++V+T WYR
Sbjct: 897 LMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYR 956
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
PELL G +Y +D+W+ GCIL EL + P +L QL I ++ G+P WP
Sbjct: 957 PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPD 1016
Query: 236 MKTLTDY--VQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS- 292
+ L + ++ K + LR FS + LL+ +L L P RC Q LQ +
Sbjct: 1017 VIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKD 1076
Query: 293 ---SKPAPSVGPKLPMPSNISKLEVEKPSLKRK 322
SK AP P LP + +L +K +R+
Sbjct: 1077 VELSKMAP---PDLPHWQDCHELWSKKRRRQRQ 1106
>BC000281-1|AAH00281.2| 283|Homo sapiens PCTK3 protein protein.
Length = 283
Score = 190 bits (462), Expect = 8e-48
Identities = 95/235 (40%), Positives = 139/235 (59%), Gaps = 2/235 (0%)
Query: 61 LLQELQHINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKG 120
LL+ L+H N++ L D+ +++LVF+++D+DL+ + +++ NVK +M L+G
Sbjct: 2 LLKNLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRG 61
Query: 121 LEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELL 180
L Y H ILHRDLKP LLIN G LK+ DFGLA+A PT+ +++VVT WYR P++L
Sbjct: 62 LAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVL 121
Query: 181 FGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLT 240
G+ +Y T +DMW VGCI E+ P PG + ++L IF++ GTPTEE WPG+ +
Sbjct: 122 LGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFS 181
Query: 241 DY--VQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
++ F + Q L + D I LL SLL +R AL +YF S
Sbjct: 182 EFRTYSFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRS 236
>AF227198-1|AAF36401.1| 1490|Homo sapiens CrkRS protein.
Length = 1490
Score = 189 bits (461), Expect = 1e-47
Identities = 111/333 (33%), Positives = 184/333 (55%), Gaps = 23/333 (6%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
+++ I +GEG + VYKA+D T ++VA+KK+++ + E G TA+REIK+L++L
Sbjct: 726 KFDIIGIIGEGTYGQVYKARDKDTGELVALKKVRLDNEKE---GFPITAIREIKILRQLI 782
Query: 67 HINLIGLLDVFGQKSNVS----------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIM 116
H +++ + ++ K + LVF++MD DL +++ + + ++K++M
Sbjct: 783 HRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQ 842
Query: 117 TLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGS-PTRINTHQVVTRWYR 175
++GLEY H+ LHRD+K + +L+N G +K+ DFGLA+ + S +R T++V+T WYR
Sbjct: 843 LMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYR 902
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
PELL G +Y +D+W+ GCIL EL + P +L QL I ++ G+P WP
Sbjct: 903 PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPD 962
Query: 236 MKTLTDY--VQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS- 292
+ L + ++ K + LR FS + LL+ +L L P RC Q LQ +
Sbjct: 963 VIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKD 1022
Query: 293 ---SKPAPSVGPKLPMPSNISKLEVEKPSLKRK 322
SK AP P LP + +L +K +R+
Sbjct: 1023 VELSKMAP---PDLPHWQDCHELWSKKRRRQRQ 1052
>M80629-1|AAA58424.1| 418|Homo sapiens cdc2-related protein kinase
protein.
Length = 418
Score = 187 bits (456), Expect = 4e-47
Identities = 101/297 (34%), Positives = 169/297 (56%), Gaps = 16/297 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
+++ I +GEG + VYKA+D T ++VA+KK+++ + E G TA+REIK+L++L
Sbjct: 90 KFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKE---GFPITAIREIKILRQLT 146
Query: 67 HINLIGLLDVFGQKSNVS----------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIM 116
H ++I + ++ K + LVF++MD DL +++ + ++K++M
Sbjct: 147 HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFYENHIKSFMRQ 206
Query: 117 TLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSP-TRINTHQVVTRWYR 175
++GL+Y H+ LHRD+K + +L+N G +K+ DFGLA+ + S +R T++V+T WYR
Sbjct: 207 LMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYR 266
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
PELL G +Y +D+W+ GCIL EL + P +L QL I ++ G+P WP
Sbjct: 267 PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPD 326
Query: 236 MKTLTDY--VQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAY 290
+ L + ++ K ++LR F + L + +LAL P RC QALQ +
Sbjct: 327 VIKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEF 383
>U35146-1|AAC50918.1| 493|Homo sapiens p56 KKIAMRE protein kinase
protein.
Length = 493
Score = 187 bits (455), Expect = 6e-47
Identities = 101/290 (34%), Positives = 161/290 (55%), Gaps = 10/290 (3%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDG--INRTALREIKLLQE 64
+YE + +GEG + V K ++ T +IVA+KK LE+ D + + A+REIKLL++
Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKF-----LESDDDKMVKKIAMREIKLLKQ 57
Query: 65 LQHINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYL 124
L+H NL+ LL+V +K LVF+F+D + ++ L V+ Y+ + G+ +
Sbjct: 58 LRHENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFC 117
Query: 125 HQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGAR 184
H + I+HRD+KP +L+++ G++K+ DFG A+ +P + T V TRWYRAPELL G
Sbjct: 118 HSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDV 177
Query: 185 QYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGT--PTEENWPGMKTLTDY 242
+YG VD+WA+GC++ E+ + P PG+SD+DQL I G P + +
Sbjct: 178 KYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAG 237
Query: 243 VQFKLFPAQE-LRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYF 291
V+ +E L + SE +I L + L + P R C + L +F
Sbjct: 238 VRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFF 287
>BC093981-1|AAH93981.1| 493|Homo sapiens cyclin-dependent
kinase-like 2 (CDC2-related kinase) protein.
Length = 493
Score = 187 bits (455), Expect = 6e-47
Identities = 101/290 (34%), Positives = 161/290 (55%), Gaps = 10/290 (3%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDG--INRTALREIKLLQE 64
+YE + +GEG + V K ++ T +IVA+KK LE+ D + + A+REIKLL++
Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKF-----LESDDDKMVKKIAMREIKLLKQ 57
Query: 65 LQHINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYL 124
L+H NL+ LL+V +K LVF+F+D + ++ L V+ Y+ + G+ +
Sbjct: 58 LRHENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFC 117
Query: 125 HQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGAR 184
H + I+HRD+KP +L+++ G++K+ DFG A+ +P + T V TRWYRAPELL G
Sbjct: 118 HSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDV 177
Query: 185 QYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGT--PTEENWPGMKTLTDY 242
+YG VD+WA+GC++ E+ + P PG+SD+DQL I G P + +
Sbjct: 178 KYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAG 237
Query: 243 VQFKLFPAQE-LRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYF 291
V+ +E L + SE +I L + L + P R C + L +F
Sbjct: 238 VRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFF 287
>BC093646-1|AAH93646.1| 493|Homo sapiens cyclin-dependent
kinase-like 2 (CDC2-related kinase) protein.
Length = 493
Score = 187 bits (455), Expect = 6e-47
Identities = 101/290 (34%), Positives = 161/290 (55%), Gaps = 10/290 (3%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDG--INRTALREIKLLQE 64
+YE + +GEG + V K ++ T +IVA+KK LE+ D + + A+REIKLL++
Sbjct: 3 KYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKF-----LESDDDKMVKKIAMREIKLLKQ 57
Query: 65 LQHINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYL 124
L+H NL+ LL+V +K LVF+F+D + ++ L V+ Y+ + G+ +
Sbjct: 58 LRHENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFC 117
Query: 125 HQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGAR 184
H + I+HRD+KP +L+++ G++K+ DFG A+ +P + T V TRWYRAPELL G
Sbjct: 118 HSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDV 177
Query: 185 QYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGT--PTEENWPGMKTLTDY 242
+YG VD+WA+GC++ E+ + P PG+SD+DQL I G P + +
Sbjct: 178 KYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAG 237
Query: 243 VQFKLFPAQE-LRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYF 291
V+ +E L + SE +I L + L + P R C + L +F
Sbjct: 238 VRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFF 287
>BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein.
Length = 592
Score = 183 bits (445), Expect = 9e-46
Identities = 107/325 (32%), Positives = 169/325 (52%), Gaps = 12/325 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
YE + +GEG + TV K K T +IVA+K + +N+ A+REIK L++ H
Sbjct: 4 YETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYE----RPEQSVNKIAMREIKFLKQFHH 59
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
NL+ L++VF QK + LVF+F+D + ++ L ++ Y+ L+ ++YLH N
Sbjct: 60 ENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSN 119
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
I+HRD+KP +L+++ GI K+ DFG A+ +P I T V TRWYRAPEL+ YG
Sbjct: 120 NIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYG 179
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFG--TPTEEN-WPGMKTLTDYVQ 244
VD+WA+GC++ E+ P+LP SDLD L +I G +P +N + V
Sbjct: 180 KPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVL 239
Query: 245 FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS-----SKPAPSV 299
++ + R + + L ++ + L + P +R + L YF+ K P +
Sbjct: 240 PQVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTRDGFIEKFMPEL 299
Query: 300 GPKLPMPSNISKLEVEKPSLKRKLL 324
KL + ++ L K S K L
Sbjct: 300 KAKLLQEAKVNSLIKPKESSKENEL 324
>AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protein
kinase NKIAMRE protein.
Length = 455
Score = 183 bits (445), Expect = 9e-46
Identities = 107/325 (32%), Positives = 169/325 (52%), Gaps = 12/325 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
YE + +GEG + TV K K T +IVA+K + +N+ A+REIK L++ H
Sbjct: 4 YETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYE----RPEQSVNKIAMREIKFLKQFHH 59
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
NL+ L++VF QK + LVF+F+D + ++ L ++ Y+ L+ ++YLH N
Sbjct: 60 ENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSN 119
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
I+HRD+KP +L+++ GI K+ DFG A+ +P I T V TRWYRAPEL+ YG
Sbjct: 120 NIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYG 179
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFG--TPTEEN-WPGMKTLTDYVQ 244
VD+WA+GC++ E+ P+LP SDLD L +I G +P +N + V
Sbjct: 180 KPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVL 239
Query: 245 FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS-----SKPAPSV 299
++ + R + + L ++ + L + P +R + L YF+ K P +
Sbjct: 240 PQVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTRDGFIEKFMPEL 299
Query: 300 GPKLPMPSNISKLEVEKPSLKRKLL 324
KL + ++ L K S K L
Sbjct: 300 KAKLLQEAKVNSLIKPKESSKENEL 324
>Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-like
5 protein.
Length = 1030
Score = 182 bits (442), Expect = 2e-45
Identities = 108/297 (36%), Positives = 168/297 (56%), Gaps = 17/297 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
++E + +GEG + V K + +T +IVA+KK K E + + T LRE+K+L+ L+
Sbjct: 12 KFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDS---EENEEVKETTLRELKMLRTLK 68
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
N++ L + F ++ + LVF++++ ++ ++++ + P VK+Y+ +K + + H+
Sbjct: 69 QENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHK 128
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRIN-THQVVTRWYRAPELLFGARQ 185
N I+HRD+KP LLI+ +LK+ DFG A+ N T V TRWYR+PELL GA
Sbjct: 129 NDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGA-P 187
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFG-TPTEENWPGMKTLTDYVQ 244
YG VDMW+VGCIL EL P PGES++DQL I +V G P+E+ MK +
Sbjct: 188 YGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQ----MKLFYSNPR 243
Query: 245 FK--LFPA----QEL-RHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSK 294
F FPA Q L R + L+ L+++LL L P +R Q L F ++
Sbjct: 244 FHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQ 300
>Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein.
Length = 1030
Score = 182 bits (442), Expect = 2e-45
Identities = 108/297 (36%), Positives = 168/297 (56%), Gaps = 17/297 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
++E + +GEG + V K + +T +IVA+KK K E + + T LRE+K+L+ L+
Sbjct: 12 KFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDS---EENEEVKETTLRELKMLRTLK 68
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
N++ L + F ++ + LVF++++ ++ ++++ + P VK+Y+ +K + + H+
Sbjct: 69 QENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHK 128
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRIN-THQVVTRWYRAPELLFGARQ 185
N I+HRD+KP LLI+ +LK+ DFG A+ N T V TRWYR+PELL GA
Sbjct: 129 NDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGA-P 187
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFG-TPTEENWPGMKTLTDYVQ 244
YG VDMW+VGCIL EL P PGES++DQL I +V G P+E+ MK +
Sbjct: 188 YGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQ----MKLFYSNPR 243
Query: 245 FK--LFPA----QEL-RHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSK 294
F FPA Q L R + L+ L+++LL L P +R Q L F ++
Sbjct: 244 FHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQ 300
>AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase 9
protein.
Length = 1030
Score = 182 bits (442), Expect = 2e-45
Identities = 108/297 (36%), Positives = 168/297 (56%), Gaps = 17/297 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
++E + +GEG + V K + +T +IVA+KK K E + + T LRE+K+L+ L+
Sbjct: 12 KFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDS---EENEEVKETTLRELKMLRTLK 68
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
N++ L + F ++ + LVF++++ ++ ++++ + P VK+Y+ +K + + H+
Sbjct: 69 QENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHK 128
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRIN-THQVVTRWYRAPELLFGARQ 185
N I+HRD+KP LLI+ +LK+ DFG A+ N T V TRWYR+PELL GA
Sbjct: 129 NDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGA-P 187
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFG-TPTEENWPGMKTLTDYVQ 244
YG VDMW+VGCIL EL P PGES++DQL I +V G P+E+ MK +
Sbjct: 188 YGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQ----MKLFYSNPR 243
Query: 245 FK--LFPA----QEL-RHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSK 294
F FPA Q L R + L+ L+++LL L P +R Q L F ++
Sbjct: 244 FHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQ 300
>AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent
kinase-like 5 protein.
Length = 1030
Score = 182 bits (442), Expect = 2e-45
Identities = 108/297 (36%), Positives = 168/297 (56%), Gaps = 17/297 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
++E + +GEG + V K + +T +IVA+KK K E + + T LRE+K+L+ L+
Sbjct: 12 KFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDS---EENEEVKETTLRELKMLRTLK 68
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
N++ L + F ++ + LVF++++ ++ ++++ + P VK+Y+ +K + + H+
Sbjct: 69 QENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHK 128
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRIN-THQVVTRWYRAPELLFGARQ 185
N I+HRD+KP LLI+ +LK+ DFG A+ N T V TRWYR+PELL GA
Sbjct: 129 NDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGA-P 187
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFG-TPTEENWPGMKTLTDYVQ 244
YG VDMW+VGCIL EL P PGES++DQL I +V G P+E+ MK +
Sbjct: 188 YGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQ----MKLFYSNPR 243
Query: 245 FK--LFPA----QEL-RHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSK 294
F FPA Q L R + L+ L+++LL L P +R Q L F ++
Sbjct: 244 FHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQ 300
>AL162581-2|CAI19518.1| 632|Homo sapiens RP1-132F22.1 protein.
Length = 632
Score = 181 bits (440), Expect = 4e-45
Identities = 98/288 (34%), Positives = 163/288 (56%), Gaps = 9/288 (3%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY I LG+G + +V + ++ +++A+KK+K ++ +N LRE+K L++L
Sbjct: 3 RYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMN---LREVKSLKKLN 58
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N++ L +V + ++ +F++M +L +IK+ + + ++ M L+GL ++H+
Sbjct: 59 HANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHK 118
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+ HRDLKP LL ++KI DFGLA+ S T V TRWYRAPE+L + Y
Sbjct: 119 HGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPY-TDYVSTRWYRAPEVLLRSTNY 177
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFK 246
+ +D+WAVGCI+AE+ P PG S++D + +I QV GTP + +WP L+ + F+
Sbjct: 178 SSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFR 237
Query: 247 LFP---AQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYF 291
+P L+ + AS + + LL +L P R +QAL+ YF
Sbjct: 238 -WPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYF 284
>AL031178-1|CAI20261.1| 632|Homo sapiens RP1-132F22.1 protein.
Length = 632
Score = 181 bits (440), Expect = 4e-45
Identities = 98/288 (34%), Positives = 163/288 (56%), Gaps = 9/288 (3%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY I LG+G + +V + ++ +++A+KK+K ++ +N LRE+K L++L
Sbjct: 3 RYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMN---LREVKSLKKLN 58
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N++ L +V + ++ +F++M +L +IK+ + + ++ M L+GL ++H+
Sbjct: 59 HANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHK 118
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+ HRDLKP LL ++KI DFGLA+ S T V TRWYRAPE+L + Y
Sbjct: 119 HGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPY-TDYVSTRWYRAPEVLLRSTNY 177
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFK 246
+ +D+WAVGCI+AE+ P PG S++D + +I QV GTP + +WP L+ + F+
Sbjct: 178 SSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFR 237
Query: 247 LFP---AQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYF 291
+P L+ + AS + + LL +L P R +QAL+ YF
Sbjct: 238 -WPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYF 284
>AF152469-1|AAG43364.1| 632|Homo sapiens MAK-related kinase
protein.
Length = 632
Score = 181 bits (440), Expect = 4e-45
Identities = 98/288 (34%), Positives = 163/288 (56%), Gaps = 9/288 (3%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY I LG+G + +V + ++ +++A+KK+K ++ +N LRE+K L++L
Sbjct: 3 RYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMN---LREVKSLKKLN 58
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N++ L +V + ++ +F++M +L +IK+ + + ++ M L+GL ++H+
Sbjct: 59 HANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHK 118
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+ HRDLKP LL ++KI DFGLA+ S T V TRWYRAPE+L + Y
Sbjct: 119 HGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPY-TDYVSTRWYRAPEVLLRSTNY 177
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFK 246
+ +D+WAVGCI+AE+ P PG S++D + +I QV GTP + +WP L+ + F+
Sbjct: 178 SSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFR 237
Query: 247 LFP---AQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYF 291
+P L+ + AS + + LL +L P R +QAL+ YF
Sbjct: 238 -WPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYF 284
>AB023153-1|BAA76780.2| 640|Homo sapiens KIAA0936 protein protein.
Length = 640
Score = 181 bits (440), Expect = 4e-45
Identities = 98/288 (34%), Positives = 163/288 (56%), Gaps = 9/288 (3%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY I LG+G + +V + ++ +++A+KK+K ++ +N LRE+K L++L
Sbjct: 11 RYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMN---LREVKSLKKLN 66
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N++ L +V + ++ +F++M +L +IK+ + + ++ M L+GL ++H+
Sbjct: 67 HANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHK 126
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+ HRDLKP LL ++KI DFGLA+ S T V TRWYRAPE+L + Y
Sbjct: 127 HGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPY-TDYVSTRWYRAPEVLLRSTNY 185
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFK 246
+ +D+WAVGCI+AE+ P PG S++D + +I QV GTP + +WP L+ + F+
Sbjct: 186 SSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFR 245
Query: 247 LFP---AQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYF 291
+P L+ + AS + + LL +L P R +QAL+ YF
Sbjct: 246 -WPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYF 292
>U81031-1|AAC39521.2| 303|Homo sapiens CDK4 protein.
Length = 303
Score = 180 bits (438), Expect = 6e-45
Identities = 107/295 (36%), Positives = 161/295 (54%), Gaps = 12/295 (4%)
Query: 5 TLRYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQE 64
T RYE + +G G + TVYKA+D + VA+K +++ + G+ + +RE+ LL+
Sbjct: 3 TSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 65 LQ---HINLIGLLDVFG-----QKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMI 115
L+ H N++ L+DV ++ V+LVF+ +D DL + PA +K M
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMR 122
Query: 116 MTLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYR 175
L+GL++LH N I+HRDLKP +L+ G +K+ DFGLA+ + + T VVT WYR
Sbjct: 123 QFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMAL-TPVVVTLWYR 181
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
APE+L + Y T VDMW+VGCI AE+ R P G S+ DQL +IF + G P E++WP
Sbjct: 182 APEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR 240
Query: 236 MKTLTDYVQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAY 290
+L F + ++ + E LL +L P R +ALQ +Y
Sbjct: 241 DVSLPRGA-FPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSY 294
>U37022-1|AAC50506.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 180 bits (438), Expect = 6e-45
Identities = 107/295 (36%), Positives = 161/295 (54%), Gaps = 12/295 (4%)
Query: 5 TLRYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQE 64
T RYE + +G G + TVYKA+D + VA+K +++ + G+ + +RE+ LL+
Sbjct: 3 TSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 65 LQ---HINLIGLLDVFG-----QKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMI 115
L+ H N++ L+DV ++ V+LVF+ +D DL + PA +K M
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMR 122
Query: 116 MTLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYR 175
L+GL++LH N I+HRDLKP +L+ G +K+ DFGLA+ + + T VVT WYR
Sbjct: 123 QFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMAL-TPVVVTLWYR 181
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
APE+L + Y T VDMW+VGCI AE+ R P G S+ DQL +IF + G P E++WP
Sbjct: 182 APEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR 240
Query: 236 MKTLTDYVQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAY 290
+L F + ++ + E LL +L P R +ALQ +Y
Sbjct: 241 DVSLPRGA-FPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSY 294
>M14505-1|AAA35673.1| 303|Homo sapiens cyclin-dependent protein
kinase, type 4 protein.
Length = 303
Score = 180 bits (438), Expect = 6e-45
Identities = 107/295 (36%), Positives = 161/295 (54%), Gaps = 12/295 (4%)
Query: 5 TLRYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQE 64
T RYE + +G G + TVYKA+D + VA+K +++ + G+ + +RE+ LL+
Sbjct: 3 TSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 65 LQ---HINLIGLLDVFG-----QKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMI 115
L+ H N++ L+DV ++ V+LVF+ +D DL + PA +K M
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMR 122
Query: 116 MTLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYR 175
L+GL++LH N I+HRDLKP +L+ G +K+ DFGLA+ + + T VVT WYR
Sbjct: 123 QFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMAL-TPVVVTLWYR 181
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
APE+L + Y T VDMW+VGCI AE+ R P G S+ DQL +IF + G P E++WP
Sbjct: 182 APEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR 240
Query: 236 MKTLTDYVQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAY 290
+L F + ++ + E LL +L P R +ALQ +Y
Sbjct: 241 DVSLPRGA-FPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSY 294
>CR542247-1|CAG47043.1| 303|Homo sapiens CDK4 protein.
Length = 303
Score = 180 bits (438), Expect = 6e-45
Identities = 107/295 (36%), Positives = 161/295 (54%), Gaps = 12/295 (4%)
Query: 5 TLRYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQE 64
T RYE + +G G + TVYKA+D + VA+K +++ + G+ + +RE+ LL+
Sbjct: 3 TSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 65 LQ---HINLIGLLDVFG-----QKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMI 115
L+ H N++ L+DV ++ V+LVF+ +D DL + PA +K M
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMR 122
Query: 116 MTLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYR 175
L+GL++LH N I+HRDLKP +L+ G +K+ DFGLA+ + + T VVT WYR
Sbjct: 123 QFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMAL-TPVVVTLWYR 181
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
APE+L + Y T VDMW+VGCI AE+ R P G S+ DQL +IF + G P E++WP
Sbjct: 182 APEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR 240
Query: 236 MKTLTDYVQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAY 290
+L F + ++ + E LL +L P R +ALQ +Y
Sbjct: 241 DVSLPRGA-FPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSY 294
>CR407668-1|CAG28596.1| 303|Homo sapiens CDK4 protein.
Length = 303
Score = 180 bits (438), Expect = 6e-45
Identities = 107/295 (36%), Positives = 161/295 (54%), Gaps = 12/295 (4%)
Query: 5 TLRYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQE 64
T RYE + +G G + TVYKA+D + VA+K +++ + G+ + +RE+ LL+
Sbjct: 3 TSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 65 LQ---HINLIGLLDVFG-----QKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMI 115
L+ H N++ L+DV ++ V+LVF+ +D DL + PA +K M
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMR 122
Query: 116 MTLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYR 175
L+GL++LH N I+HRDLKP +L+ G +K+ DFGLA+ + + T VVT WYR
Sbjct: 123 QFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMAL-TPVVVTLWYR 181
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
APE+L + Y T VDMW+VGCI AE+ R P G S+ DQL +IF + G P E++WP
Sbjct: 182 APEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR 240
Query: 236 MKTLTDYVQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAY 290
+L F + ++ + E LL +L P R +ALQ +Y
Sbjct: 241 DVSLPRGA-FPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSY 294
>BC010153-1|AAH10153.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 180 bits (438), Expect = 6e-45
Identities = 107/295 (36%), Positives = 161/295 (54%), Gaps = 12/295 (4%)
Query: 5 TLRYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQE 64
T RYE + +G G + TVYKA+D + VA+K +++ + G+ + +RE+ LL+
Sbjct: 3 TSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 65 LQ---HINLIGLLDVFG-----QKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMI 115
L+ H N++ L+DV ++ V+LVF+ +D DL + PA +K M
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMR 122
Query: 116 MTLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYR 175
L+GL++LH N I+HRDLKP +L+ G +K+ DFGLA+ + + T VVT WYR
Sbjct: 123 QFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMAL-TPVVVTLWYR 181
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
APE+L + Y T VDMW+VGCI AE+ R P G S+ DQL +IF + G P E++WP
Sbjct: 182 APEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR 240
Query: 236 MKTLTDYVQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAY 290
+L F + ++ + E LL +L P R +ALQ +Y
Sbjct: 241 DVSLPRGA-FPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSY 294
>BC005864-1|AAH05864.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 180 bits (438), Expect = 6e-45
Identities = 107/295 (36%), Positives = 161/295 (54%), Gaps = 12/295 (4%)
Query: 5 TLRYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQE 64
T RYE + +G G + TVYKA+D + VA+K +++ + G+ + +RE+ LL+
Sbjct: 3 TSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 65 LQ---HINLIGLLDVFG-----QKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMI 115
L+ H N++ L+DV ++ V+LVF+ +D DL + PA +K M
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMR 122
Query: 116 MTLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYR 175
L+GL++LH N I+HRDLKP +L+ G +K+ DFGLA+ + + T VVT WYR
Sbjct: 123 QFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMAL-TPVVVTLWYR 181
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
APE+L + Y T VDMW+VGCI AE+ R P G S+ DQL +IF + G P E++WP
Sbjct: 182 APEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR 240
Query: 236 MKTLTDYVQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAY 290
+L F + ++ + E LL +L P R +ALQ +Y
Sbjct: 241 DVSLPRGA-FPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSY 294
>BC003644-1|AAH03644.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 180 bits (438), Expect = 6e-45
Identities = 107/295 (36%), Positives = 161/295 (54%), Gaps = 12/295 (4%)
Query: 5 TLRYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQE 64
T RYE + +G G + TVYKA+D + VA+K +++ + G+ + +RE+ LL+
Sbjct: 3 TSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 65 LQ---HINLIGLLDVFG-----QKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMI 115
L+ H N++ L+DV ++ V+LVF+ +D DL + PA +K M
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMR 122
Query: 116 MTLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYR 175
L+GL++LH N I+HRDLKP +L+ G +K+ DFGLA+ + + T VVT WYR
Sbjct: 123 QFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMAL-TPVVVTLWYR 181
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
APE+L + Y T VDMW+VGCI AE+ R P G S+ DQL +IF + G P E++WP
Sbjct: 182 APEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR 240
Query: 236 MKTLTDYVQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAY 290
+L F + ++ + E LL +L P R +ALQ +Y
Sbjct: 241 DVSLPRGA-FPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSY 294
>AF507942-1|AAM23014.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 180 bits (438), Expect = 6e-45
Identities = 107/295 (36%), Positives = 161/295 (54%), Gaps = 12/295 (4%)
Query: 5 TLRYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQE 64
T RYE + +G G + TVYKA+D + VA+K +++ + G+ + +RE+ LL+
Sbjct: 3 TSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 65 LQ---HINLIGLLDVFG-----QKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMI 115
L+ H N++ L+DV ++ V+LVF+ +D DL + PA +K M
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMR 122
Query: 116 MTLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYR 175
L+GL++LH N I+HRDLKP +L+ G +K+ DFGLA+ + + T VVT WYR
Sbjct: 123 QFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMAL-TPVVVTLWYR 181
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
APE+L + Y T VDMW+VGCI AE+ R P G S+ DQL +IF + G P E++WP
Sbjct: 182 APEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR 240
Query: 236 MKTLTDYVQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAY 290
+L F + ++ + E LL +L P R +ALQ +Y
Sbjct: 241 DVSLPRGA-FPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSY 294
>AL353572-3|CAH72843.1| 325|Homo sapiens cell cycle related kinase
protein.
Length = 325
Score = 179 bits (436), Expect = 1e-44
Identities = 116/301 (38%), Positives = 163/301 (54%), Gaps = 30/301 (9%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHIN-LIG 72
+GEG V+KAK +T +IVA+KK+ + RLE DG ALREIK LQE++ ++
Sbjct: 10 IGEGAHGIVFKAKHVETGEIVALKKVAL-RRLE--DGFPNQALREIKALQEMEDNQYVVQ 66
Query: 73 LLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQNWILHR 132
L VF L F+FM +DL +++ L A VK+Y+ M LKG+ + H N I+HR
Sbjct: 67 LKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHANNIVHR 126
Query: 133 DLKPNTLLINREGILKIGDFGLAKAFG-SPTRINTHQVVTRWYRAPELLFGARQYGTGVD 191
DLKP LLI+ G LKI DFGLA+ F +R+ THQV TR
Sbjct: 127 DLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR------------------- 167
Query: 192 MWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDY--VQFKLFP 249
+VGCI+ ELL P PG++D++QL + ++ GTP + WP + L DY + FK
Sbjct: 168 --SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQV 225
Query: 250 AQELRHIFSAASEDLIFLLESLLALYPPN-RCDCTQALQMAYFSSKPAPSVGPKLPMPSN 308
L + S + LL L LYPP+ R ++AL YF + P P+ +LP+P
Sbjct: 226 PMPLEEVLPDVSPQALDLLGQFL-LYPPHQRIAASKALLHQYFFTAPLPAHPSELPIPQR 284
Query: 309 I 309
+
Sbjct: 285 L 285
>AF113130-1|AAF43778.1| 452|Homo sapiens cyclin-dependent protein
kinase H protein.
Length = 452
Score = 179 bits (435), Expect = 1e-44
Identities = 115/301 (38%), Positives = 163/301 (54%), Gaps = 30/301 (9%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHIN-LIG 72
+GEG V+KAK +T +I+A+KK+ + RLE DG ALREIK LQE++ ++
Sbjct: 10 IGEGAHGIVFKAKHVETGEIIALKKVAL-RRLE--DGFPNQALREIKALQEMEDNQYVVQ 66
Query: 73 LLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQNWILHR 132
L VF L F+FM +DL +++ L A VK+Y+ M LKG+ + H N I+HR
Sbjct: 67 LKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHANNIVHR 126
Query: 133 DLKPNTLLINREGILKIGDFGLAKAFG-SPTRINTHQVVTRWYRAPELLFGARQYGTGVD 191
DLKP LLI+ G LKI DFGLA+ F +R+ THQV TR
Sbjct: 127 DLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR------------------- 167
Query: 192 MWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDY--VQFKLFP 249
+VGCI+ ELL P PG++D++QL + ++ GTP + WP + L DY + FK
Sbjct: 168 --SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQV 225
Query: 250 AQELRHIFSAASEDLIFLLESLLALYPPN-RCDCTQALQMAYFSSKPAPSVGPKLPMPSN 308
L + S + LL L LYPP+ R ++AL YF + P P+ +LP+P
Sbjct: 226 PMPLEEVLPDVSPQALDLLGQFL-LYPPHQRIAASKALLHQYFFTAPLPAHPSELPIPQR 284
Query: 309 I 309
+
Sbjct: 285 L 285
>AF035013-1|AAC98920.1| 452|Homo sapiens cell cycle related kinase
protein.
Length = 452
Score = 179 bits (435), Expect = 1e-44
Identities = 115/301 (38%), Positives = 163/301 (54%), Gaps = 30/301 (9%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHIN-LIG 72
+GEG V+KAK +T +I+A+KK+ + RLE DG ALREIK LQE++ ++
Sbjct: 10 IGEGAHGIVFKAKHVETGEIIALKKVAL-RRLE--DGFPNQALREIKALQEMEDNQYVVQ 66
Query: 73 LLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQNWILHR 132
L VF L F+FM +DL +++ L A VK+Y+ M LKG+ + H N I+HR
Sbjct: 67 LKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHANNIVHR 126
Query: 133 DLKPNTLLINREGILKIGDFGLAKAFG-SPTRINTHQVVTRWYRAPELLFGARQYGTGVD 191
DLKP LLI+ G LKI DFGLA+ F +R+ THQV TR
Sbjct: 127 DLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR------------------- 167
Query: 192 MWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDY--VQFKLFP 249
+VGCI+ ELL P PG++D++QL + ++ GTP + WP + L DY + FK
Sbjct: 168 --SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQV 225
Query: 250 AQELRHIFSAASEDLIFLLESLLALYPPN-RCDCTQALQMAYFSSKPAPSVGPKLPMPSN 308
L + S + LL L LYPP+ R ++AL YF + P P+ +LP+P
Sbjct: 226 PMPLEEVLPDVSPQALDLLGQFL-LYPPHQRIAASKALLHQYFFTAPLPAHPSELPIPQR 284
Query: 309 I 309
+
Sbjct: 285 L 285
>Z48970-1|CAA88834.1| 303|Homo sapiens orf protein.
Length = 303
Score = 178 bits (433), Expect = 3e-44
Identities = 107/295 (36%), Positives = 160/295 (54%), Gaps = 12/295 (4%)
Query: 5 TLRYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQE 64
T RYE + +G G + TVYKA D + VA+K +++ + G+ + +RE+ LL+
Sbjct: 3 TSRYEPVAEIGVGAYGTVYKACDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRR 62
Query: 65 LQ---HINLIGLLDVFG-----QKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMI 115
L+ H N++ L+DV ++ V+LVF+ +D DL + PA +K M
Sbjct: 63 LEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMR 122
Query: 116 MTLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYR 175
L+GL++LH N I+HRDLKP +L+ G +K+ DFGLA+ + + T VVT WYR
Sbjct: 123 QFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMAL-TPVVVTLWYR 181
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
APE+L + Y T VDMW+VGCI AE+ R P G S+ DQL +IF + G P E++WP
Sbjct: 182 APEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR 240
Query: 236 MKTLTDYVQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAY 290
+L F + ++ + E LL +L P R +ALQ +Y
Sbjct: 241 DVSLPRGA-FPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSY 294
>AF225919-1|AAF37278.1| 632|Homo sapiens intestinal cell kinase
protein.
Length = 632
Score = 178 bits (433), Expect = 3e-44
Identities = 97/288 (33%), Positives = 162/288 (56%), Gaps = 9/288 (3%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY I LG+G + +V + ++ +++A+KK+K ++ +N+ RE+K L++L
Sbjct: 3 RYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMNQ---REVKSLKKLN 58
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N++ L +V + ++ +F++M +L +IK+ + + ++ M L+GL ++H+
Sbjct: 59 HANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHK 118
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
HRDLKP LL ++KI DFGLA+ S T V TRWYRAPE+L + Y
Sbjct: 119 LGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPY-TDYVSTRWYRAPEVLLRSTNY 177
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFK 246
+ +D+WAVGCI+AE+ P PG S++D + +I QV GTP + +WP L+ + F+
Sbjct: 178 SSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFR 237
Query: 247 LFP---AQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYF 291
+P L+ + AS + + LL +L P R +QAL+ YF
Sbjct: 238 -WPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYF 284
>Z11695-1|CAA77753.1| 348|Homo sapiens 40kDa protein kinase
protein.
Length = 348
Score = 177 bits (432), Expect = 3e-44
Identities = 116/332 (34%), Positives = 172/332 (51%), Gaps = 19/332 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY + ++GEG + V A D VA+KKI S E Q RT LREIK+L +
Sbjct: 12 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKI---SPFEHQTYCQRT-LREIKILLRFR 67
Query: 67 HINLIGLLDVFG-----QKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
H N+IG+ D+ Q +V +V D M+TDL ++K T L+ ++ ++ L+GL
Sbjct: 68 HENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLK--TQHLSNDHICYFLYQILRGL 125
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSP---TRINTHQVVTRWYRAPE 178
+Y+H +LHRDLKP+ LL+N LKI DFGLA+ T T V TRWYRAPE
Sbjct: 126 KYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPE 185
Query: 179 LLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT 238
++ ++ Y +D+W+VGCILAE+L P PG+ LDQL+ I + G+P++E+ +
Sbjct: 186 IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN 245
Query: 239 LTDYVQFKLFPAQE---LRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKP 295
L P + +F A + LL+ +L P R + QAL Y
Sbjct: 246 LKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYY 305
Query: 296 APSVGP--KLPMPSNISKLEVEKPSLKRKLLD 325
PS P + P ++ ++ K LK + +
Sbjct: 306 DPSDEPIAEAPFKFDMELDDLPKEKLKELIFE 337
>Z11694-1|CAA77752.1| 360|Homo sapiens 41kD protein kinase protein.
Length = 360
Score = 177 bits (432), Expect = 3e-44
Identities = 116/332 (34%), Positives = 172/332 (51%), Gaps = 19/332 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY + ++GEG + V A D VA+KKI S E Q RT LREIK+L +
Sbjct: 24 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKI---SPFEHQTYCQRT-LREIKILLRFR 79
Query: 67 HINLIGLLDVFG-----QKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
H N+IG+ D+ Q +V +V D M+TDL ++K T L+ ++ ++ L+GL
Sbjct: 80 HENIIGINDIIQAPTIEQMKDVYIVQDLMETDLYKLLK--TQHLSNDHICYFLYQILRGL 137
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSP---TRINTHQVVTRWYRAPE 178
+Y+H +LHRDLKP+ LL+N LKI DFGLA+ T T V TRWYRAPE
Sbjct: 138 KYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPE 197
Query: 179 LLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT 238
++ ++ Y +D+W+VGCILAE+L P PG+ LDQL+ I + G+P++E+ +
Sbjct: 198 IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN 257
Query: 239 LTDYVQFKLFPAQE---LRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKP 295
L P + +F A + LL+ +L P R + QAL Y
Sbjct: 258 LKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYY 317
Query: 296 APSVGP--KLPMPSNISKLEVEKPSLKRKLLD 325
PS P + P ++ ++ K LK + +
Sbjct: 318 DPSDEPIAEAPFKFDMELDDLPKEKLKELIFE 349
>M84489-1|AAA58459.1| 360|Homo sapiens protein kinase 2 protein.
Length = 360
Score = 177 bits (432), Expect = 3e-44
Identities = 116/332 (34%), Positives = 172/332 (51%), Gaps = 19/332 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY + ++GEG + V A D VA+KKI S E Q RT LREIK+L +
Sbjct: 24 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKI---SPFEHQTYCQRT-LREIKILLRFR 79
Query: 67 HINLIGLLDVFG-----QKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
H N+IG+ D+ Q +V +V D M+TDL ++K T L+ ++ ++ L+GL
Sbjct: 80 HENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLK--TQHLSNDHICYFLYQILRGL 137
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSP---TRINTHQVVTRWYRAPE 178
+Y+H +LHRDLKP+ LL+N LKI DFGLA+ T T V TRWYRAPE
Sbjct: 138 KYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPE 197
Query: 179 LLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT 238
++ ++ Y +D+W+VGCILAE+L P PG+ LDQL+ I + G+P++E+ +
Sbjct: 198 IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN 257
Query: 239 LTDYVQFKLFPAQE---LRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKP 295
L P + +F A + LL+ +L P R + QAL Y
Sbjct: 258 LKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYY 317
Query: 296 APSVGP--KLPMPSNISKLEVEKPSLKRKLLD 325
PS P + P ++ ++ K LK + +
Sbjct: 318 DPSDEPIAEAPFKFDMELDDLPKEKLKELIFE 349
>DQ508104-1|ABF47102.1| 360|Homo sapiens mitogen-activated protein
kinase 1 protein.
Length = 360
Score = 177 bits (432), Expect = 3e-44
Identities = 116/332 (34%), Positives = 172/332 (51%), Gaps = 19/332 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY + ++GEG + V A D VA+KKI S E Q RT LREIK+L +
Sbjct: 24 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKI---SPFEHQTYCQRT-LREIKILLRFR 79
Query: 67 HINLIGLLDVFG-----QKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
H N+IG+ D+ Q +V +V D M+TDL ++K T L+ ++ ++ L+GL
Sbjct: 80 HENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLK--TQHLSNDHICYFLYQILRGL 137
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSP---TRINTHQVVTRWYRAPE 178
+Y+H +LHRDLKP+ LL+N LKI DFGLA+ T T V TRWYRAPE
Sbjct: 138 KYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPE 197
Query: 179 LLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT 238
++ ++ Y +D+W+VGCILAE+L P PG+ LDQL+ I + G+P++E+ +
Sbjct: 198 IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN 257
Query: 239 LTDYVQFKLFPAQE---LRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKP 295
L P + +F A + LL+ +L P R + QAL Y
Sbjct: 258 LKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYY 317
Query: 296 APSVGP--KLPMPSNISKLEVEKPSLKRKLLD 325
PS P + P ++ ++ K LK + +
Sbjct: 318 DPSDEPIAEAPFKFDMELDDLPKEKLKELIFE 349
>BC017832-1|AAH17832.1| 360|Homo sapiens mitogen-activated protein
kinase 1 protein.
Length = 360
Score = 177 bits (432), Expect = 3e-44
Identities = 116/332 (34%), Positives = 172/332 (51%), Gaps = 19/332 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY + ++GEG + V A D VA+KKI S E Q RT LREIK+L +
Sbjct: 24 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKI---SPFEHQTYCQRT-LREIKILLRFR 79
Query: 67 HINLIGLLDVFG-----QKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
H N+IG+ D+ Q +V +V D M+TDL ++K T L+ ++ ++ L+GL
Sbjct: 80 HENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLK--TQHLSNDHICYFLYQILRGL 137
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSP---TRINTHQVVTRWYRAPE 178
+Y+H +LHRDLKP+ LL+N LKI DFGLA+ T T V TRWYRAPE
Sbjct: 138 KYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPE 197
Query: 179 LLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT 238
++ ++ Y +D+W+VGCILAE+L P PG+ LDQL+ I + G+P++E+ +
Sbjct: 198 IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN 257
Query: 239 LTDYVQFKLFPAQE---LRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKP 295
L P + +F A + LL+ +L P R + QAL Y
Sbjct: 258 LKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYY 317
Query: 296 APSVGP--KLPMPSNISKLEVEKPSLKRKLLD 325
PS P + P ++ ++ K LK + +
Sbjct: 318 DPSDEPIAEAPFKFDMELDDLPKEKLKELIFE 349
>BC039825-1|AAH39825.1| 457|Homo sapiens MAK protein protein.
Length = 457
Score = 177 bits (431), Expect = 5e-44
Identities = 99/288 (34%), Positives = 162/288 (56%), Gaps = 9/288 (3%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY + LG+G + +V K ++ ++VA+K++K + + D LRE+K L++L
Sbjct: 3 RYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMK--RKFYSWDECMN--LREVKSLKKLN 58
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N+I L +V + ++ +F++M +L ++KD + + ++ M L+GL ++H+
Sbjct: 59 HANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHK 118
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+ HRD+KP LL ++KI DFGLA+ S T V TRWYRAPE+L + Y
Sbjct: 119 HGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPY-TDYVSTRWYRAPEVLLRSSVY 177
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFK 246
+ +D+WAVG I+AEL + P PG S++D++ +I QV GTP + +WP L + F+
Sbjct: 178 SSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFR 237
Query: 247 LFP---AQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYF 291
FP L+ + AS + I L+ +L P R +QAL+ YF
Sbjct: 238 -FPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYF 284
>AL024498-4|CAB75823.1| 623|Homo sapiens protein ( Human DNA
sequence from clone RP3-417M14 on chromosome 6p23-25.1.
).
Length = 623
Score = 177 bits (431), Expect = 5e-44
Identities = 99/288 (34%), Positives = 162/288 (56%), Gaps = 9/288 (3%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY + LG+G + +V K ++ ++VA+K++K + + D LRE+K L++L
Sbjct: 3 RYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMK--RKFYSWDECMN--LREVKSLKKLN 58
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N+I L +V + ++ +F++M +L ++KD + + ++ M L+GL ++H+
Sbjct: 59 HANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHK 118
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+ HRD+KP LL ++KI DFGLA+ S T V TRWYRAPE+L + Y
Sbjct: 119 HGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPY-TDYVSTRWYRAPEVLLRSSVY 177
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFK 246
+ +D+WAVG I+AEL + P PG S++D++ +I QV GTP + +WP L + F+
Sbjct: 178 SSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFR 237
Query: 247 LFP---AQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYF 291
FP L+ + AS + I L+ +L P R +QAL+ YF
Sbjct: 238 -FPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYF 284
>AF505623-1|AAN16405.1| 623|Homo sapiens male germ cell-associated
kinase protein.
Length = 623
Score = 177 bits (431), Expect = 5e-44
Identities = 99/288 (34%), Positives = 162/288 (56%), Gaps = 9/288 (3%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY + LG+G + +V K ++ ++VA+K++K + + D LRE+K L++L
Sbjct: 3 RYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMK--RKFYSWDECMN--LREVKSLKKLN 58
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N+I L +V + ++ +F++M +L ++KD + + ++ M L+GL ++H+
Sbjct: 59 HANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHK 118
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+ HRD+KP LL ++KI DFGLA+ S T V TRWYRAPE+L + Y
Sbjct: 119 HGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPY-TDYVSTRWYRAPEVLLRSSVY 177
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFK 246
+ +D+WAVG I+AEL + P PG S++D++ +I QV GTP + +WP L + F+
Sbjct: 178 SSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFR 237
Query: 247 LFP---AQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYF 291
FP L+ + AS + I L+ +L P R +QAL+ YF
Sbjct: 238 -FPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYF 284
>AY065978-1|AAL40897.1| 544|Homo sapiens extracellular
signal-regulated kinase 8 protein.
Length = 544
Score = 176 bits (428), Expect = 1e-43
Identities = 112/297 (37%), Positives = 160/297 (53%), Gaps = 16/297 (5%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQEL-QHINLIG 72
LG+G + V+KA D +T ++VA+KKI R + D RT REI LLQE H N+I
Sbjct: 19 LGQGAYGIVWKAVDRRTGEVVAIKKIFDAFR-DKTDA-QRT-FREITLLQEFGDHPNIIS 75
Query: 73 LLDVFGQKSN--VSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQNWIL 130
LLDV +++ + LVF+FMDTDL +I+ + L +V++ L+ +LH ++
Sbjct: 76 LLDVIRAENDRDIYLVFEFMDTDLNAVIRKGGL-LQDVHVRSIFYQLLRATRFLHSGHVV 134
Query: 131 HRDLKPNTLLINREGILKIGDFGLAKAFGS-----PTRINTHQVVTRWYRAPELLFGARQ 185
HRD KP+ +L++ +K+ DFGLA++ G + T V TRWYRAPE+L + +
Sbjct: 135 HRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEVLLSSHR 194
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT---LTDY 242
Y GVDMW++GCIL E+L P PG S L QL I + P+EE+ + + +
Sbjct: 195 YTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEEDLLALGSGCRASVL 254
Query: 243 VQFKLFPAQELRHIFSA-ASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPS 298
Q P Q L + S + + LL LL P R TQALQ Y PS
Sbjct: 255 HQLGSRPRQTLDALLPPDTSPEALDLLRRLLVFAPDKRLSATQALQHPYVQRFHCPS 311
>AK131512-1|BAD18656.1| 345|Homo sapiens protein ( Homo sapiens
cDNA FLJ16732 fis, clone BNGH42005017, moderately
similar to SERINE/THREONINE-PROTEIN KINASE PCTAIRE-1 (EC
2.7.1.-). ).
Length = 345
Score = 176 bits (428), Expect = 1e-43
Identities = 92/236 (38%), Positives = 137/236 (58%), Gaps = 26/236 (11%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y ++ LGEG +ATVYK ++VA+K I + A++G+ TA+RE LL+ L+H
Sbjct: 103 YLNLEKLGEGSYATVYKGISRINGQLVALKVIS----MNAEEGVPFTAIREASLLKGLKH 158
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
N++ L D+ K ++ VF++M +M L+GL Y+H
Sbjct: 159 ANIVLLHDIIHTKETLTFVFEYM---------------------LFMFQLLRGLAYIHHQ 197
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
+LHRDLKP LLI+ G LK+ DFGLA+A P++ + +VVT WYR P+ L GA +Y
Sbjct: 198 HVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYS 257
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESD-LDQLSRIFQVFGTPTEENWPGMKTLTDY 242
+ +D+W GCI E+ P PG S+ L+QL +I++V G PTE+ WPG+ L +Y
Sbjct: 258 SELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNY 313
>BC099905-1|AAH99905.1| 360|Homo sapiens mitogen-activated protein
kinase 1 protein.
Length = 360
Score = 175 bits (426), Expect = 2e-43
Identities = 115/332 (34%), Positives = 172/332 (51%), Gaps = 19/332 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY + ++GEG + V A D VA+KKI S E Q RT LREIK+L +
Sbjct: 24 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKI---SPFEHQTYCQRT-LREIKILLRSR 79
Query: 67 HINLIGLLDVFG-----QKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
H N+IG+ D+ Q +V +V D M+TDL ++K T L+ ++ ++ L+GL
Sbjct: 80 HENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLK--TQHLSNDHICYFLYQILRGL 137
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSP---TRINTHQVVTRWYRAPE 178
+Y+H +LHRDLKP+ LL+N L+I DFGLA+ T T V TRWYRAPE
Sbjct: 138 KYIHSANVLHRDLKPSNLLLNTTCDLEICDFGLARVADPDHDHTGFLTEYVATRWYRAPE 197
Query: 179 LLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT 238
++ ++ Y +D+W+VGCILAE+L P PG+ LDQL+ I + G+P++E+ +
Sbjct: 198 IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN 257
Query: 239 LTDYVQFKLFPAQE---LRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKP 295
L P + +F A + LL+ +L P R + QAL Y
Sbjct: 258 LKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYY 317
Query: 296 APSVGP--KLPMPSNISKLEVEKPSLKRKLLD 325
PS P + P ++ ++ K LK + +
Sbjct: 318 DPSDEPIAEAPFKFDMELDDLPKEKLKELIFE 349
>Z84480-1|CAI20520.1| 502|Homo sapiens cell division cycle 2-like 6
(CDK8-like) protein.
Length = 502
Score = 174 bits (424), Expect = 3e-43
Identities = 132/337 (39%), Positives = 176/337 (52%), Gaps = 53/337 (15%)
Query: 14 LGEGQFATVYKA--KDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLI 71
+G G + VYKA KD K +K A+K+I+ G+ GI+ +A REI LL+EL+H N+I
Sbjct: 27 VGRGTYGHVYKARRKDGKDEKEYALKQIE-GT------GISMSACREIALLRELKHPNVI 79
Query: 72 GLLDVFGQKSN--VSLVFDFMDTDLEIIIK--------DNTIVLTPANVKAYMIMTLKGL 121
L VF S+ V L+FD+ + DL IIK + L + VK+ + L G+
Sbjct: 80 ALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGI 139
Query: 122 EYLHQNWILHRDLKPNTLLINREGI----LKIGDFGLAKAFGSPTRINTHQ---VVTRWY 174
YLH NW+LHRDLKP +L+ EG +KI D G A+ F SP + VVT WY
Sbjct: 140 HYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWY 199
Query: 175 RAPELLFGARQYGTGVDMWAVGCILAELLLRVP-FLPGESDL--------DQLSRIFQVF 225
RAPELL GAR Y +D+WA+GCI AELL P F + D+ DQL RIF V
Sbjct: 200 RAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVM 259
Query: 226 GTPTEENW------PGMKTL------TDYVQFKLFPAQELRHIFSAASEDLIFLLESLLA 273
G P +++W P TL T Y L E +H S+ + LL+ LL
Sbjct: 260 GFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYME-KHKVKPDSK-VFLLLQKLLT 317
Query: 274 LYPPNRCDCTQALQMAYFSSKPAPSV----GPKLPMP 306
+ P R QALQ YF P P++ G ++P P
Sbjct: 318 MDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYP 354
>X66365-1|CAA47008.1| 326|Homo sapiens serine/threonine protein
kinase protein.
Length = 326
Score = 174 bits (424), Expect = 3e-43
Identities = 108/318 (33%), Positives = 168/318 (52%), Gaps = 18/318 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTD-KIVAVKKIKIGSRLEAQDGINRTALREIKLLQEL 65
+YE + +GEG + V+KA+D K + VA+K++++ + ++G+ + +RE+ +L+ L
Sbjct: 12 QYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQT---GEEGMPLSTIREVAVLRHL 68
Query: 66 Q---HINLIGLLDVF-----GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMIM 116
+ H N++ L DV +++ ++LVF+ +D DL + P +K M
Sbjct: 69 ETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQ 128
Query: 117 TLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRA 176
L+GL++LH + ++HRDLKP +L+ G +K+ DFGLA+ + + T VVT WYRA
Sbjct: 129 LLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMAL-TSVVVTLWYRA 187
Query: 177 PELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGM 236
PE+L + Y T VD+W+VGCI AE+ R P G SD+DQL +I V G P EE+WP
Sbjct: 188 PEVLLQS-SYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRD 246
Query: 237 KTLTDYVQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS--SK 294
L F AQ + + E LL L P R AL YF +
Sbjct: 247 VALPRQA-FHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLER 305
Query: 295 PAPSVGPKLPMPSNISKL 312
++ LP N S+L
Sbjct: 306 CKENLDSHLPPSQNTSEL 323
>BC052264-1|AAH52264.1| 326|Homo sapiens cyclin-dependent kinase 6
protein.
Length = 326
Score = 174 bits (424), Expect = 3e-43
Identities = 108/318 (33%), Positives = 168/318 (52%), Gaps = 18/318 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTD-KIVAVKKIKIGSRLEAQDGINRTALREIKLLQEL 65
+YE + +GEG + V+KA+D K + VA+K++++ + ++G+ + +RE+ +L+ L
Sbjct: 12 QYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQT---GEEGMPLSTIREVAVLRHL 68
Query: 66 Q---HINLIGLLDVF-----GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMIM 116
+ H N++ L DV +++ ++LVF+ +D DL + P +K M
Sbjct: 69 ETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQ 128
Query: 117 TLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRA 176
L+GL++LH + ++HRDLKP +L+ G +K+ DFGLA+ + + T VVT WYRA
Sbjct: 129 LLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMAL-TSVVVTLWYRA 187
Query: 177 PELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGM 236
PE+L + Y T VD+W+VGCI AE+ R P G SD+DQL +I V G P EE+WP
Sbjct: 188 PEVLLQS-SYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRD 246
Query: 237 KTLTDYVQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS--SK 294
L F AQ + + E LL L P R AL YF +
Sbjct: 247 VALPRQA-FHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLER 305
Query: 295 PAPSVGPKLPMPSNISKL 312
++ LP N S+L
Sbjct: 306 CKENLDSHLPPSQNTSEL 323
>BC037289-1|AAH37289.1| 502|Homo sapiens CDC2L6 protein protein.
Length = 502
Score = 174 bits (424), Expect = 3e-43
Identities = 132/337 (39%), Positives = 176/337 (52%), Gaps = 53/337 (15%)
Query: 14 LGEGQFATVYKA--KDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLI 71
+G G + VYKA KD K +K A+K+I+ G+ GI+ +A REI LL+EL+H N+I
Sbjct: 27 VGRGTYGHVYKARRKDGKDEKEYALKQIE-GT------GISMSACREIALLRELKHPNVI 79
Query: 72 GLLDVFGQKSN--VSLVFDFMDTDLEIIIK--------DNTIVLTPANVKAYMIMTLKGL 121
L VF S+ V L+FD+ + DL IIK + L + VK+ + L G+
Sbjct: 80 ALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGI 139
Query: 122 EYLHQNWILHRDLKPNTLLINREGI----LKIGDFGLAKAFGSPTRINTHQ---VVTRWY 174
YLH NW+LHRDLKP +L+ EG +KI D G A+ F SP + VVT WY
Sbjct: 140 HYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWY 199
Query: 175 RAPELLFGARQYGTGVDMWAVGCILAELLLRVP-FLPGESDL--------DQLSRIFQVF 225
RAPELL GAR Y +D+WA+GCI AELL P F + D+ DQL RIF V
Sbjct: 200 RAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVM 259
Query: 226 GTPTEENW------PGMKTL------TDYVQFKLFPAQELRHIFSAASEDLIFLLESLLA 273
G P +++W P TL T Y L E +H S+ + LL+ LL
Sbjct: 260 GFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYME-KHKVKPDSK-VFLLLQKLLT 317
Query: 274 LYPPNRCDCTQALQMAYFSSKPAPSV----GPKLPMP 306
+ P R QALQ YF P P++ G ++P P
Sbjct: 318 MDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYP 354
>AY128534-1|AAM76970.1| 326|Homo sapiens cyclin-dependent kinase 6
protein.
Length = 326
Score = 174 bits (424), Expect = 3e-43
Identities = 108/318 (33%), Positives = 168/318 (52%), Gaps = 18/318 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTD-KIVAVKKIKIGSRLEAQDGINRTALREIKLLQEL 65
+YE + +GEG + V+KA+D K + VA+K++++ + ++G+ + +RE+ +L+ L
Sbjct: 12 QYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQT---GEEGMPLSTIREVAVLRHL 68
Query: 66 Q---HINLIGLLDVF-----GQKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMIM 116
+ H N++ L DV +++ ++LVF+ +D DL + P +K M
Sbjct: 69 ETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQ 128
Query: 117 TLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRA 176
L+GL++LH + ++HRDLKP +L+ G +K+ DFGLA+ + + T VVT WYRA
Sbjct: 129 LLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMAL-TSVVVTLWYRA 187
Query: 177 PELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGM 236
PE+L + Y T VD+W+VGCI AE+ R P G SD+DQL +I V G P EE+WP
Sbjct: 188 PEVLLQS-SYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRD 246
Query: 237 KTLTDYVQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS--SK 294
L F AQ + + E LL L P R AL YF +
Sbjct: 247 VALPRQA-FHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLER 305
Query: 295 PAPSVGPKLPMPSNISKL 312
++ LP N S+L
Sbjct: 306 CKENLDSHLPPSQNTSEL 323
>AY028424-1|AAK27731.1| 502|Homo sapiens death-preventing kinase
protein.
Length = 502
Score = 174 bits (424), Expect = 3e-43
Identities = 132/337 (39%), Positives = 176/337 (52%), Gaps = 53/337 (15%)
Query: 14 LGEGQFATVYKA--KDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLI 71
+G G + VYKA KD K +K A+K+I+ G+ GI+ +A REI LL+EL+H N+I
Sbjct: 27 VGRGTYGHVYKARRKDGKDEKEYALKQIE-GT------GISMSACREIALLRELKHPNVI 79
Query: 72 GLLDVFGQKSN--VSLVFDFMDTDLEIIIK--------DNTIVLTPANVKAYMIMTLKGL 121
L VF S+ V L+FD+ + DL IIK + L + VK+ + L G+
Sbjct: 80 ALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGI 139
Query: 122 EYLHQNWILHRDLKPNTLLINREGI----LKIGDFGLAKAFGSPTRINTHQ---VVTRWY 174
YLH NW+LHRDLKP +L+ EG +KI D G A+ F SP + VVT WY
Sbjct: 140 HYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWY 199
Query: 175 RAPELLFGARQYGTGVDMWAVGCILAELLLRVP-FLPGESDL--------DQLSRIFQVF 225
RAPELL GAR Y +D+WA+GCI AELL P F + D+ DQL RIF V
Sbjct: 200 RAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVM 259
Query: 226 GTPTEENW------PGMKTL------TDYVQFKLFPAQELRHIFSAASEDLIFLLESLLA 273
G P +++W P TL T Y L E +H S+ + LL+ LL
Sbjct: 260 GFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYME-KHKVKPDSK-VFLLLQKLLT 317
Query: 274 LYPPNRCDCTQALQMAYFSSKPAPSV----GPKLPMP 306
+ P R QALQ YF P P++ G ++P P
Sbjct: 318 MDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYP 354
>AL603914-4|CAI41175.1| 502|Homo sapiens cell division cycle 2-like
6 (CDK8-like) protein.
Length = 502
Score = 174 bits (424), Expect = 3e-43
Identities = 132/337 (39%), Positives = 176/337 (52%), Gaps = 53/337 (15%)
Query: 14 LGEGQFATVYKA--KDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLI 71
+G G + VYKA KD K +K A+K+I+ G+ GI+ +A REI LL+EL+H N+I
Sbjct: 27 VGRGTYGHVYKARRKDGKDEKEYALKQIE-GT------GISMSACREIALLRELKHPNVI 79
Query: 72 GLLDVFGQKSN--VSLVFDFMDTDLEIIIK--------DNTIVLTPANVKAYMIMTLKGL 121
L VF S+ V L+FD+ + DL IIK + L + VK+ + L G+
Sbjct: 80 ALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGI 139
Query: 122 EYLHQNWILHRDLKPNTLLINREGI----LKIGDFGLAKAFGSPTRINTHQ---VVTRWY 174
YLH NW+LHRDLKP +L+ EG +KI D G A+ F SP + VVT WY
Sbjct: 140 HYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWY 199
Query: 175 RAPELLFGARQYGTGVDMWAVGCILAELLLRVP-FLPGESDL--------DQLSRIFQVF 225
RAPELL GAR Y +D+WA+GCI AELL P F + D+ DQL RIF V
Sbjct: 200 RAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVM 259
Query: 226 GTPTEENW------PGMKTL------TDYVQFKLFPAQELRHIFSAASEDLIFLLESLLA 273
G P +++W P TL T Y L E +H S+ + LL+ LL
Sbjct: 260 GFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYME-KHKVKPDSK-VFLLLQKLLT 317
Query: 274 LYPPNRCDCTQALQMAYFSSKPAPSV----GPKLPMP 306
+ P R QALQ YF P P++ G ++P P
Sbjct: 318 MDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYP 354
>AL512430-4|CAI40286.1| 502|Homo sapiens cell division cycle 2-like
6 (CDK8-like) protein.
Length = 502
Score = 174 bits (424), Expect = 3e-43
Identities = 132/337 (39%), Positives = 176/337 (52%), Gaps = 53/337 (15%)
Query: 14 LGEGQFATVYKA--KDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLI 71
+G G + VYKA KD K +K A+K+I+ G+ GI+ +A REI LL+EL+H N+I
Sbjct: 27 VGRGTYGHVYKARRKDGKDEKEYALKQIE-GT------GISMSACREIALLRELKHPNVI 79
Query: 72 GLLDVFGQKSN--VSLVFDFMDTDLEIIIK--------DNTIVLTPANVKAYMIMTLKGL 121
L VF S+ V L+FD+ + DL IIK + L + VK+ + L G+
Sbjct: 80 ALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGI 139
Query: 122 EYLHQNWILHRDLKPNTLLINREGI----LKIGDFGLAKAFGSPTRINTHQ---VVTRWY 174
YLH NW+LHRDLKP +L+ EG +KI D G A+ F SP + VVT WY
Sbjct: 140 HYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWY 199
Query: 175 RAPELLFGARQYGTGVDMWAVGCILAELLLRVP-FLPGESDL--------DQLSRIFQVF 225
RAPELL GAR Y +D+WA+GCI AELL P F + D+ DQL RIF V
Sbjct: 200 RAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVM 259
Query: 226 GTPTEENW------PGMKTL------TDYVQFKLFPAQELRHIFSAASEDLIFLLESLLA 273
G P +++W P TL T Y L E +H S+ + LL+ LL
Sbjct: 260 GFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYME-KHKVKPDSK-VFLLLQKLLT 317
Query: 274 LYPPNRCDCTQALQMAYFSSKPAPSV----GPKLPMP 306
+ P R QALQ YF P P++ G ++P P
Sbjct: 318 MDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYP 354
>AB028951-1|BAA82980.2| 501|Homo sapiens KIAA1028 protein protein.
Length = 501
Score = 174 bits (424), Expect = 3e-43
Identities = 132/337 (39%), Positives = 176/337 (52%), Gaps = 53/337 (15%)
Query: 14 LGEGQFATVYKA--KDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLI 71
+G G + VYKA KD K +K A+K+I+ G+ GI+ +A REI LL+EL+H N+I
Sbjct: 26 VGRGTYGHVYKARRKDGKDEKEYALKQIE-GT------GISMSACREIALLRELKHPNVI 78
Query: 72 GLLDVFGQKSN--VSLVFDFMDTDLEIIIK--------DNTIVLTPANVKAYMIMTLKGL 121
L VF S+ V L+FD+ + DL IIK + L + VK+ + L G+
Sbjct: 79 ALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGI 138
Query: 122 EYLHQNWILHRDLKPNTLLINREGI----LKIGDFGLAKAFGSPTRINTHQ---VVTRWY 174
YLH NW+LHRDLKP +L+ EG +KI D G A+ F SP + VVT WY
Sbjct: 139 HYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWY 198
Query: 175 RAPELLFGARQYGTGVDMWAVGCILAELLLRVP-FLPGESDL--------DQLSRIFQVF 225
RAPELL GAR Y +D+WA+GCI AELL P F + D+ DQL RIF V
Sbjct: 199 RAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVM 258
Query: 226 GTPTEENW------PGMKTL------TDYVQFKLFPAQELRHIFSAASEDLIFLLESLLA 273
G P +++W P TL T Y L E +H S+ + LL+ LL
Sbjct: 259 GFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYME-KHKVKPDSK-VFLLLQKLLT 316
Query: 274 LYPPNRCDCTQALQMAYFSSKPAPSV----GPKLPMP 306
+ P R QALQ YF P P++ G ++P P
Sbjct: 317 MDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYP 353
>DQ411039-1|ABD66016.1| 260|Homo sapiens protein kinase CDK5
splicing variant protein.
Length = 260
Score = 173 bits (422), Expect = 6e-43
Identities = 109/288 (37%), Positives = 160/288 (55%), Gaps = 37/288 (12%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
+YEK++ +GEG + TV+KAK+ +T +IVA+K++++ + +G+ +ALREI LL+EL+
Sbjct: 3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLD---DDDEGVPSSALREICLLKELK 59
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N+ + D + +D ++ + V + LK +Y
Sbjct: 60 H-------------KNIVRLHDVLHSDKKLTL-----------VFEFCDQDLK--KYFDS 93
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+ DL P I + G LK+ DFGLA+AFG P R + +VVT WYR P++LFGA+ Y
Sbjct: 94 ---CNGDLDPE---IVKNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLY 147
Query: 187 GTGVDMWAVGCILAELL-LRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQF 245
T +DMW+ GCI AEL P PG DQL RIF++ GTPTEE WP M L DY +
Sbjct: 148 STSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPY 207
Query: 246 KLFPA-QELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS 292
++PA L ++ + LL++LL P R +ALQ YFS
Sbjct: 208 PMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFS 255
>U29727-1|AAA82933.1| 816|Homo sapiens BMK1 gamma kinase protein.
Length = 816
Score = 173 bits (420), Expect = 1e-42
Identities = 107/313 (34%), Positives = 163/313 (52%), Gaps = 19/313 (6%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
YE I+ +G G + V A+ T + VA+KKI + + RT LRE+K+L+ +H
Sbjct: 55 YEIIETIGNGAYGVVSSARRRLTGQQVAIKKIP--NAFDVVTNAKRT-LRELKILKHFKH 111
Query: 68 INLIGLLDV------FGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
N+I + D+ +G+ +V +V D M++DL II + LT +V+ ++ L+GL
Sbjct: 112 DNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQ-PLTLEHVRYFLYQLLRGL 170
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAF-GSPTR---INTHQVVTRWYRAP 177
+Y+H ++HRDLKP+ LL+N LKIGDFG+A+ SP T V TRWYRAP
Sbjct: 171 KYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAP 230
Query: 178 ELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEE--NWPG 235
EL+ +Y +D+W+VGCI E+L R PG++ + QL I V GTP+ G
Sbjct: 231 ELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVG 290
Query: 236 MKTLTDYVQFKLFPAQEL--RHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+ + Y+Q L P Q + ++ A + LL +L P R AL+ + +
Sbjct: 291 AERVRAYIQ-SLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAK 349
Query: 294 KPAPSVGPKLPMP 306
P P P
Sbjct: 350 YHDPDDEPDCAPP 362
>U29726-1|AAA82932.1| 816|Homo sapiens BMK1 beta kinase protein.
Length = 816
Score = 173 bits (420), Expect = 1e-42
Identities = 107/313 (34%), Positives = 163/313 (52%), Gaps = 19/313 (6%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
YE I+ +G G + V A+ T + VA+KKI + + RT LRE+K+L+ +H
Sbjct: 55 YEIIETIGNGAYGVVSSARRRLTGQQVAIKKIP--NAFDVVTNAKRT-LRELKILKHFKH 111
Query: 68 INLIGLLDV------FGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
N+I + D+ +G+ +V +V D M++DL II + LT +V+ ++ L+GL
Sbjct: 112 DNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQ-PLTLEHVRYFLYQLLRGL 170
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAF-GSPTR---INTHQVVTRWYRAP 177
+Y+H ++HRDLKP+ LL+N LKIGDFG+A+ SP T V TRWYRAP
Sbjct: 171 KYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAP 230
Query: 178 ELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEE--NWPG 235
EL+ +Y +D+W+VGCI E+L R PG++ + QL I V GTP+ G
Sbjct: 231 ELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVG 290
Query: 236 MKTLTDYVQFKLFPAQEL--RHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+ + Y+Q L P Q + ++ A + LL +L P R AL+ + +
Sbjct: 291 AERVRAYIQ-SLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAK 349
Query: 294 KPAPSVGPKLPMP 306
P P P
Sbjct: 350 YHDPDDEPDCAPP 362
>U29725-1|AAA82931.1| 816|Homo sapiens BMK1 alpha kinase protein.
Length = 816
Score = 173 bits (420), Expect = 1e-42
Identities = 107/313 (34%), Positives = 163/313 (52%), Gaps = 19/313 (6%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
YE I+ +G G + V A+ T + VA+KKI + + RT LRE+K+L+ +H
Sbjct: 55 YEIIETIGNGAYGVVSSARRRLTGQQVAIKKIP--NAFDVVTNAKRT-LRELKILKHFKH 111
Query: 68 INLIGLLDV------FGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
N+I + D+ +G+ +V +V D M++DL II + LT +V+ ++ L+GL
Sbjct: 112 DNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQ-PLTLEHVRYFLYQLLRGL 170
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAF-GSPTR---INTHQVVTRWYRAP 177
+Y+H ++HRDLKP+ LL+N LKIGDFG+A+ SP T V TRWYRAP
Sbjct: 171 KYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAP 230
Query: 178 ELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEE--NWPG 235
EL+ +Y +D+W+VGCI E+L R PG++ + QL I V GTP+ G
Sbjct: 231 ELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVG 290
Query: 236 MKTLTDYVQFKLFPAQEL--RHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+ + Y+Q L P Q + ++ A + LL +L P R AL+ + +
Sbjct: 291 AERVRAYIQ-SLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAK 349
Query: 294 KPAPSVGPKLPMP 306
P P P
Sbjct: 350 YHDPDDEPDCAPP 362
>U25278-1|AAA81381.1| 815|Homo sapiens ERK5 protein.
Length = 815
Score = 173 bits (420), Expect = 1e-42
Identities = 107/313 (34%), Positives = 163/313 (52%), Gaps = 19/313 (6%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
YE I+ +G G + V A+ T + VA+KKI + + RT LRE+K+L+ +H
Sbjct: 54 YEIIETIGNGAYGVVSSARRRLTGQQVAIKKIP--NAFDVVTNAKRT-LRELKILKHFKH 110
Query: 68 INLIGLLDV------FGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
N+I + D+ +G+ +V +V D M++DL II + LT +V+ ++ L+GL
Sbjct: 111 DNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQ-PLTLEHVRYFLYQLLRGL 169
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAF-GSPTR---INTHQVVTRWYRAP 177
+Y+H ++HRDLKP+ LL+N LKIGDFG+A+ SP T V TRWYRAP
Sbjct: 170 KYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAP 229
Query: 178 ELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEE--NWPG 235
EL+ +Y +D+W+VGCI E+L R PG++ + QL I V GTP+ G
Sbjct: 230 ELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVG 289
Query: 236 MKTLTDYVQFKLFPAQEL--RHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+ + Y+Q L P Q + ++ A + LL +L P R AL+ + +
Sbjct: 290 AERVRAYIQ-SLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAK 348
Query: 294 KPAPSVGPKLPMP 306
P P P
Sbjct: 349 YHDPDDEPDCAPP 361
>BC035807-1|AAH35807.1| 292|Homo sapiens ICK protein protein.
Length = 292
Score = 173 bits (420), Expect = 1e-42
Identities = 94/281 (33%), Positives = 158/281 (56%), Gaps = 9/281 (3%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY I LG+G + +V + ++ +++A+KK+K ++ +N LRE+K L++L
Sbjct: 3 RYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMK-RKFYSWEECMN---LREVKSLKKLN 58
Query: 67 HINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
H N++ L +V + ++ +F++M +L +IK+ + + ++ M L+GL ++H+
Sbjct: 59 HANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHK 118
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
+ HRDLKP LL ++KI DFGLA+ S T V TRWYRAPE+L + Y
Sbjct: 119 HGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPY-TDYVSTRWYRAPEVLLRSTNY 177
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFK 246
+ +D+WAVGCI+AE+ P PG S++D + +I QV GTP + +WP L+ + F+
Sbjct: 178 SSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFR 237
Query: 247 LFP---AQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQ 284
+P L+ + AS + + LL +L P R +Q
Sbjct: 238 -WPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQ 277
>BC030134-1|AAH30134.1| 816|Homo sapiens mitogen-activated protein
kinase 7 protein.
Length = 816
Score = 173 bits (420), Expect = 1e-42
Identities = 107/313 (34%), Positives = 163/313 (52%), Gaps = 19/313 (6%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
YE I+ +G G + V A+ T + VA+KKI + + RT LRE+K+L+ +H
Sbjct: 55 YEIIETIGNGAYGVVSSARRRLTGQQVAIKKIP--NAFDVVTNAKRT-LRELKILKHFKH 111
Query: 68 INLIGLLDV------FGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
N+I + D+ +G+ +V +V D M++DL II + LT +V+ ++ L+GL
Sbjct: 112 DNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQ-PLTLEHVRYFLYQLLRGL 170
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAF-GSPTR---INTHQVVTRWYRAP 177
+Y+H ++HRDLKP+ LL+N LKIGDFG+A+ SP T V TRWYRAP
Sbjct: 171 KYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAP 230
Query: 178 ELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEE--NWPG 235
EL+ +Y +D+W+VGCI E+L R PG++ + QL I V GTP+ G
Sbjct: 231 ELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVG 290
Query: 236 MKTLTDYVQFKLFPAQEL--RHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+ + Y+Q L P Q + ++ A + LL +L P R AL+ + +
Sbjct: 291 AERVRAYIQ-SLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAK 349
Query: 294 KPAPSVGPKLPMP 306
P P P
Sbjct: 350 YHDPDDEPDCAPP 362
>BC009963-1|AAH09963.1| 816|Homo sapiens mitogen-activated protein
kinase 7 protein.
Length = 816
Score = 173 bits (420), Expect = 1e-42
Identities = 107/313 (34%), Positives = 163/313 (52%), Gaps = 19/313 (6%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
YE I+ +G G + V A+ T + VA+KKI + + RT LRE+K+L+ +H
Sbjct: 55 YEIIETIGNGAYGVVSSARRRLTGQQVAIKKIP--NAFDVVTNAKRT-LRELKILKHFKH 111
Query: 68 INLIGLLDV------FGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
N+I + D+ +G+ +V +V D M++DL II + LT +V+ ++ L+GL
Sbjct: 112 DNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQ-PLTLEHVRYFLYQLLRGL 170
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAF-GSPTR---INTHQVVTRWYRAP 177
+Y+H ++HRDLKP+ LL+N LKIGDFG+A+ SP T V TRWYRAP
Sbjct: 171 KYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAP 230
Query: 178 ELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEE--NWPG 235
EL+ +Y +D+W+VGCI E+L R PG++ + QL I V GTP+ G
Sbjct: 231 ELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVG 290
Query: 236 MKTLTDYVQFKLFPAQEL--RHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+ + Y+Q L P Q + ++ A + LL +L P R AL+ + +
Sbjct: 291 AERVRAYIQ-SLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAK 349
Query: 294 KPAPSVGPKLPMP 306
P P P
Sbjct: 350 YHDPDDEPDCAPP 362
>AY534741-1|AAS38577.1| 533|Homo sapiens mitogen activated protein
kinase 7 transcript variant 5 protein.
Length = 533
Score = 173 bits (420), Expect = 1e-42
Identities = 107/313 (34%), Positives = 163/313 (52%), Gaps = 19/313 (6%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
YE I+ +G G + V A+ T + VA+KKI + + RT LRE+K+L+ +H
Sbjct: 55 YEIIETIGNGAYGVVSSARRRLTGQQVAIKKIP--NAFDVVTNAKRT-LRELKILKHFKH 111
Query: 68 INLIGLLDV------FGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
N+I + D+ +G+ +V +V D M++DL II + LT +V+ ++ L+GL
Sbjct: 112 DNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQ-PLTLEHVRYFLYQLLRGL 170
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAF-GSPTR---INTHQVVTRWYRAP 177
+Y+H ++HRDLKP+ LL+N LKIGDFG+A+ SP T V TRWYRAP
Sbjct: 171 KYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAP 230
Query: 178 ELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEE--NWPG 235
EL+ +Y +D+W+VGCI E+L R PG++ + QL I V GTP+ G
Sbjct: 231 ELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVG 290
Query: 236 MKTLTDYVQFKLFPAQEL--RHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
+ + Y+Q L P Q + ++ A + LL +L P R AL+ + +
Sbjct: 291 AERVRAYIQ-SLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAK 349
Query: 294 KPAPSVGPKLPMP 306
P P P
Sbjct: 350 YHDPDDEPDCAPP 362
>L35264-1|AAA57456.1| 360|Homo sapiens CSaids binding protein
protein.
Length = 360
Score = 172 bits (418), Expect = 2e-42
Identities = 113/304 (37%), Positives = 160/304 (52%), Gaps = 17/304 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY+ + +G G + +V A D KT VAVKK+ ++ RT RE++LL+ ++
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLS--RPFQSIIHAKRT-YRELRLLKHMK 79
Query: 67 HINLIGLLDVFG------QKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKG 120
H N+IGLLDVF + ++V LV M DL I+K LT +V+ + L+G
Sbjct: 80 HENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQK--LTDDHVQFLIYQILRG 137
Query: 121 LEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELL 180
L+Y+H I+HRDLKP+ L +N + LKI DFGLA+ T V TRWYRAPE++
Sbjct: 138 LKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEM---TGYVATRWYRAPEIM 194
Query: 181 FGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEE--NWPGMKT 238
Y VD+W+VGCI+AELL PG +DQL I ++ GTP E ++
Sbjct: 195 LNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSES 254
Query: 239 LTDYVQ-FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAP 297
+Y+Q P ++F A+ + LLE +L L R QAL AYF+ P
Sbjct: 255 ARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDP 314
Query: 298 SVGP 301
P
Sbjct: 315 DDEP 318
>L35253-1|AAA74301.1| 360|Homo sapiens MAP kinase protein.
Length = 360
Score = 172 bits (418), Expect = 2e-42
Identities = 113/304 (37%), Positives = 160/304 (52%), Gaps = 17/304 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY+ + +G G + +V A D KT VAVKK+ ++ RT RE++LL+ ++
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLS--RPFQSIIHAKRT-YRELRLLKHMK 79
Query: 67 HINLIGLLDVFG------QKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKG 120
H N+IGLLDVF + ++V LV M DL I+K LT +V+ + L+G
Sbjct: 80 HENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQK--LTDDHVQFLIYQILRG 137
Query: 121 LEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELL 180
L+Y+H I+HRDLKP+ L +N + LKI DFGLA+ T V TRWYRAPE++
Sbjct: 138 LKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEM---TGYVATRWYRAPEIM 194
Query: 181 FGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEE--NWPGMKT 238
Y VD+W+VGCI+AELL PG +DQL I ++ GTP E ++
Sbjct: 195 LNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSES 254
Query: 239 LTDYVQ-FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAP 297
+Y+Q P ++F A+ + LLE +L L R QAL AYF+ P
Sbjct: 255 ARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDP 314
Query: 298 SVGP 301
P
Sbjct: 315 DDEP 318
>CR536505-1|CAG38743.1| 360|Homo sapiens MAPK14 protein.
Length = 360
Score = 172 bits (418), Expect = 2e-42
Identities = 113/304 (37%), Positives = 160/304 (52%), Gaps = 17/304 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY+ + +G G + +V A D KT VAVKK+ ++ RT RE++LL+ ++
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLS--RPFQSIIHAKRT-YRELRLLKHMK 79
Query: 67 HINLIGLLDVFG------QKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKG 120
H N+IGLLDVF + ++V LV M DL I+K LT +V+ + L+G
Sbjct: 80 HENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQK--LTDDHVQFLIYQILRG 137
Query: 121 LEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELL 180
L+Y+H I+HRDLKP+ L +N + LKI DFGLA+ T V TRWYRAPE++
Sbjct: 138 LKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEM---TGYVATRWYRAPEIM 194
Query: 181 FGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEE--NWPGMKT 238
Y VD+W+VGCI+AELL PG +DQL I ++ GTP E ++
Sbjct: 195 LNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSES 254
Query: 239 LTDYVQ-FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAP 297
+Y+Q P ++F A+ + LLE +L L R QAL AYF+ P
Sbjct: 255 ARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDP 314
Query: 298 SVGP 301
P
Sbjct: 315 DDEP 318
>BT006933-1|AAP35579.1| 360|Homo sapiens mitogen-activated protein
kinase 14 protein.
Length = 360
Score = 172 bits (418), Expect = 2e-42
Identities = 113/304 (37%), Positives = 160/304 (52%), Gaps = 17/304 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY+ + +G G + +V A D KT VAVKK+ ++ RT RE++LL+ ++
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLS--RPFQSIIHAKRT-YRELRLLKHMK 79
Query: 67 HINLIGLLDVFG------QKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKG 120
H N+IGLLDVF + ++V LV M DL I+K LT +V+ + L+G
Sbjct: 80 HENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQK--LTDDHVQFLIYQILRG 137
Query: 121 LEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELL 180
L+Y+H I+HRDLKP+ L +N + LKI DFGLA+ T V TRWYRAPE++
Sbjct: 138 LKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEM---TGYVATRWYRAPEIM 194
Query: 181 FGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEE--NWPGMKT 238
Y VD+W+VGCI+AELL PG +DQL I ++ GTP E ++
Sbjct: 195 LNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSES 254
Query: 239 LTDYVQ-FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAP 297
+Y+Q P ++F A+ + LLE +L L R QAL AYF+ P
Sbjct: 255 ARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDP 314
Query: 298 SVGP 301
P
Sbjct: 315 DDEP 318
>BC031574-1|AAH31574.1| 360|Homo sapiens mitogen-activated protein
kinase 14 protein.
Length = 360
Score = 172 bits (418), Expect = 2e-42
Identities = 113/304 (37%), Positives = 160/304 (52%), Gaps = 17/304 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY+ + +G G + +V A D KT VAVKK+ ++ RT RE++LL+ ++
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLS--RPFQSIIHAKRT-YRELRLLKHMK 79
Query: 67 HINLIGLLDVFG------QKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKG 120
H N+IGLLDVF + ++V LV M DL I+K LT +V+ + L+G
Sbjct: 80 HENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQK--LTDDHVQFLIYQILRG 137
Query: 121 LEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELL 180
L+Y+H I+HRDLKP+ L +N + LKI DFGLA+ T V TRWYRAPE++
Sbjct: 138 LKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEM---TGYVATRWYRAPEIM 194
Query: 181 FGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEE--NWPGMKT 238
Y VD+W+VGCI+AELL PG +DQL I ++ GTP E ++
Sbjct: 195 LNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSES 254
Query: 239 LTDYVQ-FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAP 297
+Y+Q P ++F A+ + LLE +L L R QAL AYF+ P
Sbjct: 255 ARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDP 314
Query: 298 SVGP 301
P
Sbjct: 315 DDEP 318
>BC000092-1|AAH00092.1| 360|Homo sapiens mitogen-activated protein
kinase 14 protein.
Length = 360
Score = 172 bits (418), Expect = 2e-42
Identities = 113/304 (37%), Positives = 160/304 (52%), Gaps = 17/304 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY+ + +G G + +V A D KT VAVKK+ ++ RT RE++LL+ ++
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLS--RPFQSIIHAKRT-YRELRLLKHMK 79
Query: 67 HINLIGLLDVFG------QKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKG 120
H N+IGLLDVF + ++V LV M DL I+K LT +V+ + L+G
Sbjct: 80 HENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQK--LTDDHVQFLIYQILRG 137
Query: 121 LEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELL 180
L+Y+H I+HRDLKP+ L +N + LKI DFGLA+ T V TRWYRAPE++
Sbjct: 138 LKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEM---TGYVATRWYRAPEIM 194
Query: 181 FGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEE--NWPGMKT 238
Y VD+W+VGCI+AELL PG +DQL I ++ GTP E ++
Sbjct: 195 LNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSES 254
Query: 239 LTDYVQ-FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAP 297
+Y+Q P ++F A+ + LLE +L L R QAL AYF+ P
Sbjct: 255 ARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDP 314
Query: 298 SVGP 301
P
Sbjct: 315 DDEP 318
>AF100544-1|AAF36770.1| 360|Homo sapiens stress-activated protein
kinase 2a protein.
Length = 360
Score = 172 bits (418), Expect = 2e-42
Identities = 113/304 (37%), Positives = 160/304 (52%), Gaps = 17/304 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY+ + +G G + +V A D KT VAVKK+ ++ RT RE++LL+ ++
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLS--RPFQSIIHAKRT-YRELRLLKHMK 79
Query: 67 HINLIGLLDVFG------QKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKG 120
H N+IGLLDVF + ++V LV M DL I+K LT +V+ + L+G
Sbjct: 80 HENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQK--LTDDHVQFLIYQILRG 137
Query: 121 LEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELL 180
L+Y+H I+HRDLKP+ L +N + LKI DFGLA+ T V TRWYRAPE++
Sbjct: 138 LKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEM---TGYVATRWYRAPEIM 194
Query: 181 FGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEE--NWPGMKT 238
Y VD+W+VGCI+AELL PG +DQL I ++ GTP E ++
Sbjct: 195 LNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSES 254
Query: 239 LTDYVQ-FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAP 297
+Y+Q P ++F A+ + LLE +L L R QAL AYF+ P
Sbjct: 255 ARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDP 314
Query: 298 SVGP 301
P
Sbjct: 315 DDEP 318
>Y14440-1|CAA74792.1| 364|Homo sapiens stress activated protein
kinase-2b protein.
Length = 364
Score = 171 bits (416), Expect = 3e-42
Identities = 116/299 (38%), Positives = 160/299 (53%), Gaps = 19/299 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGIN-RTALREIKLLQELQHINLIG 72
+G G + +V A DA+ + VAVKK+ SR Q I+ R RE++LL+ L+H N+IG
Sbjct: 30 VGSGAYGSVCSAYDARLRQKVAVKKL---SR-PFQSLIHARRTYRELRLLKHLKHENVIG 85
Query: 73 LLDVFGQK------SNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
LLDVF S V LV M DL I+K L+ +V+ + L+GL+Y+H
Sbjct: 86 LLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQA--LSDEHVQFLVYQLLRGLKYIHS 143
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
I+HRDLKP+ + +N + L+I DFGLA+ T V TRWYRAPE++ Y
Sbjct: 144 AGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM---TGYVATRWYRAPEIMLNWMHY 200
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT--LTDYVQ 244
VD+W+VGCI+AELL PG +DQL RI +V GTP+ E + + Y+Q
Sbjct: 201 NQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQ 260
Query: 245 -FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPK 302
P ++L IF A+ I LL +L L R +AL AYFS P P+
Sbjct: 261 SLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPE 319
>X85753-1|CAA59754.1| 464|Homo sapiens CDK8 protein kinase protein.
Length = 464
Score = 171 bits (416), Expect = 3e-42
Identities = 132/351 (37%), Positives = 178/351 (50%), Gaps = 54/351 (15%)
Query: 14 LGEGQFATVYKAK--DAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLI 71
+G G + VYKAK D K DK A+K+I+ G+ GI+ +A REI LL+EL+H N+I
Sbjct: 27 VGRGTYGHVYKAKRKDGKDDKDYALKQIE-GT------GISMSACREIALLRELKHPNVI 79
Query: 72 GLLDVFGQKSN--VSLVFDFMDTDLEIIIK--------DNTIVLTPANVKAYMIMTLKGL 121
L VF ++ V L+FD+ + DL IIK + L VK+ + L G+
Sbjct: 80 SLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGI 139
Query: 122 EYLHQNWILHRDLKPNTLLINREGI----LKIGDFGLAKAFGSPTRINTHQ---VVTRWY 174
YLH NW+LHRDLKP +L+ EG +KI D G A+ F SP + VVT WY
Sbjct: 140 HYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWY 199
Query: 175 RAPELLFGARQYGTGVDMWAVGCILAELLLRVP-FLPGESDL--------DQLSRIFQVF 225
RAPELL GAR Y +D+WA+GCI AELL P F + D+ DQL RIF V
Sbjct: 200 RAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVM 259
Query: 226 GTPTEENWPGMKTLTD------------YVQFKLFPAQELRHIFSAASEDLIFLLESLLA 273
G P +++W +K + + Y L E +H S+ LL+ LL
Sbjct: 260 GFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYME-KHKVKPDSK-AFHLLQKLLT 317
Query: 274 LYPPNRCDCTQALQMAYFSSKPAPS----VGPKLPMPSNISKLEVEKPSLK 320
+ P R QA+Q YF P P+ G ++P P L E+P K
Sbjct: 318 MDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKR-EFLTEEEPDDK 367
>U92268-1|AAB66313.1| 364|Homo sapiens mitogen activated protein
kinase p38-2 protein.
Length = 364
Score = 171 bits (416), Expect = 3e-42
Identities = 116/299 (38%), Positives = 160/299 (53%), Gaps = 19/299 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGIN-RTALREIKLLQELQHINLIG 72
+G G + +V A DA+ + VAVKK+ SR Q I+ R RE++LL+ L+H N+IG
Sbjct: 30 VGSGAYGSVCSAYDARLRQKVAVKKL---SR-PFQSLIHARRTYRELRLLKHLKHENVIG 85
Query: 73 LLDVFGQK------SNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
LLDVF S V LV M DL I+K L+ +V+ + L+GL+Y+H
Sbjct: 86 LLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQA--LSDEHVQFLVYQLLRGLKYIHS 143
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
I+HRDLKP+ + +N + L+I DFGLA+ T V TRWYRAPE++ Y
Sbjct: 144 AGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM---TGYVATRWYRAPEIMLNWMHY 200
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT--LTDYVQ 244
VD+W+VGCI+AELL PG +DQL RI +V GTP+ E + + Y+Q
Sbjct: 201 NQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQ 260
Query: 245 -FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPK 302
P ++L IF A+ I LL +L L R +AL AYFS P P+
Sbjct: 261 SLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPE 319
>DQ279722-1|ABB72677.1| 364|Homo sapiens mitogen-activated protein
kinase 11 protein.
Length = 364
Score = 171 bits (416), Expect = 3e-42
Identities = 116/299 (38%), Positives = 160/299 (53%), Gaps = 19/299 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGIN-RTALREIKLLQELQHINLIG 72
+G G + +V A DA+ + VAVKK+ SR Q I+ R RE++LL+ L+H N+IG
Sbjct: 30 VGSGAYGSVCSAYDARLRQKVAVKKL---SR-PFQSLIHARRTYRELRLLKHLKHENVIG 85
Query: 73 LLDVFGQK------SNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
LLDVF S V LV M DL I+K L+ +V+ + L+GL+Y+H
Sbjct: 86 LLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQA--LSDEHVQFLVYQLLRGLKYIHS 143
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
I+HRDLKP+ + +N + L+I DFGLA+ T V TRWYRAPE++ Y
Sbjct: 144 AGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM---TGYVATRWYRAPEIMLNWMHY 200
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT--LTDYVQ 244
VD+W+VGCI+AELL PG +DQL RI +V GTP+ E + + Y+Q
Sbjct: 201 NQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQ 260
Query: 245 -FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPK 302
P ++L IF A+ I LL +L L R +AL AYFS P P+
Sbjct: 261 SLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPE 319
>CR456514-1|CAG30400.1| 364|Homo sapiens MAPK11 protein.
Length = 364
Score = 171 bits (416), Expect = 3e-42
Identities = 116/299 (38%), Positives = 160/299 (53%), Gaps = 19/299 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGIN-RTALREIKLLQELQHINLIG 72
+G G + +V A DA+ + VAVKK+ SR Q I+ R RE++LL+ L+H N+IG
Sbjct: 30 VGSGAYGSVCSAYDARLRQKVAVKKL---SR-PFQSLIHARRTYRELRLLKHLKHENVIG 85
Query: 73 LLDVFGQK------SNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
LLDVF S V LV M DL I+K L+ +V+ + L+GL+Y+H
Sbjct: 86 LLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQA--LSDEHVQFLVYQLLRGLKYIHS 143
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
I+HRDLKP+ + +N + L+I DFGLA+ T V TRWYRAPE++ Y
Sbjct: 144 AGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM---TGYVATRWYRAPEIMLNWMHY 200
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT--LTDYVQ 244
VD+W+VGCI+AELL PG +DQL RI +V GTP+ E + + Y+Q
Sbjct: 201 NQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQ 260
Query: 245 -FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPK 302
P ++L IF A+ I LL +L L R +AL AYFS P P+
Sbjct: 261 SLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPE 319
>BC107601-1|AAI07602.1| 463|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 463
Score = 171 bits (416), Expect = 3e-42
Identities = 132/351 (37%), Positives = 178/351 (50%), Gaps = 54/351 (15%)
Query: 14 LGEGQFATVYKAK--DAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLI 71
+G G + VYKAK D K DK A+K+I+ G+ GI+ +A REI LL+EL+H N+I
Sbjct: 27 VGRGTYGHVYKAKRKDGKDDKDYALKQIE-GT------GISMSACREIALLRELKHPNVI 79
Query: 72 GLLDVFGQKSN--VSLVFDFMDTDLEIIIK--------DNTIVLTPANVKAYMIMTLKGL 121
L VF ++ V L+FD+ + DL IIK + L VK+ + L G+
Sbjct: 80 SLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGI 139
Query: 122 EYLHQNWILHRDLKPNTLLINREGI----LKIGDFGLAKAFGSPTRINTHQ---VVTRWY 174
YLH NW+LHRDLKP +L+ EG +KI D G A+ F SP + VVT WY
Sbjct: 140 HYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWY 199
Query: 175 RAPELLFGARQYGTGVDMWAVGCILAELLLRVP-FLPGESDL--------DQLSRIFQVF 225
RAPELL GAR Y +D+WA+GCI AELL P F + D+ DQL RIF V
Sbjct: 200 RAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVM 259
Query: 226 GTPTEENWPGMKTLTD------------YVQFKLFPAQELRHIFSAASEDLIFLLESLLA 273
G P +++W +K + + Y L E +H S+ LL+ LL
Sbjct: 260 GFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYME-KHKVKPDSK-AFHLLQKLLT 317
Query: 274 LYPPNRCDCTQALQMAYFSSKPAPS----VGPKLPMPSNISKLEVEKPSLK 320
+ P R QA+Q YF P P+ G ++P P L E+P K
Sbjct: 318 MDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKR-EFLTEEEPDDK 367
>BC105950-1|AAI05951.1| 463|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 463
Score = 171 bits (416), Expect = 3e-42
Identities = 132/351 (37%), Positives = 178/351 (50%), Gaps = 54/351 (15%)
Query: 14 LGEGQFATVYKAK--DAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLI 71
+G G + VYKAK D K DK A+K+I+ G+ GI+ +A REI LL+EL+H N+I
Sbjct: 27 VGRGTYGHVYKAKRKDGKDDKDYALKQIE-GT------GISMSACREIALLRELKHPNVI 79
Query: 72 GLLDVFGQKSN--VSLVFDFMDTDLEIIIK--------DNTIVLTPANVKAYMIMTLKGL 121
L VF ++ V L+FD+ + DL IIK + L VK+ + L G+
Sbjct: 80 SLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGI 139
Query: 122 EYLHQNWILHRDLKPNTLLINREGI----LKIGDFGLAKAFGSPTRINTHQ---VVTRWY 174
YLH NW+LHRDLKP +L+ EG +KI D G A+ F SP + VVT WY
Sbjct: 140 HYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWY 199
Query: 175 RAPELLFGARQYGTGVDMWAVGCILAELLLRVP-FLPGESDL--------DQLSRIFQVF 225
RAPELL GAR Y +D+WA+GCI AELL P F + D+ DQL RIF V
Sbjct: 200 RAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVM 259
Query: 226 GTPTEENWPGMKTLTD------------YVQFKLFPAQELRHIFSAASEDLIFLLESLLA 273
G P +++W +K + + Y L E +H S+ LL+ LL
Sbjct: 260 GFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYME-KHKVKPDSK-AFHLLQKLLT 317
Query: 274 LYPPNRCDCTQALQMAYFSSKPAPS----VGPKLPMPSNISKLEVEKPSLK 320
+ P R QA+Q YF P P+ G ++P P L E+P K
Sbjct: 318 MDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKR-EFLTEEEPDDK 367
>BC104492-1|AAI04493.1| 464|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 464
Score = 171 bits (416), Expect = 3e-42
Identities = 132/351 (37%), Positives = 178/351 (50%), Gaps = 54/351 (15%)
Query: 14 LGEGQFATVYKAK--DAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLI 71
+G G + VYKAK D K DK A+K+I+ G+ GI+ +A REI LL+EL+H N+I
Sbjct: 27 VGRGTYGHVYKAKRKDGKDDKDYALKQIE-GT------GISMSACREIALLRELKHPNVI 79
Query: 72 GLLDVFGQKSN--VSLVFDFMDTDLEIIIK--------DNTIVLTPANVKAYMIMTLKGL 121
L VF ++ V L+FD+ + DL IIK + L VK+ + L G+
Sbjct: 80 SLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGI 139
Query: 122 EYLHQNWILHRDLKPNTLLINREGI----LKIGDFGLAKAFGSPTRINTHQ---VVTRWY 174
YLH NW+LHRDLKP +L+ EG +KI D G A+ F SP + VVT WY
Sbjct: 140 HYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWY 199
Query: 175 RAPELLFGARQYGTGVDMWAVGCILAELLLRVP-FLPGESDL--------DQLSRIFQVF 225
RAPELL GAR Y +D+WA+GCI AELL P F + D+ DQL RIF V
Sbjct: 200 RAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVM 259
Query: 226 GTPTEENWPGMKTLTD------------YVQFKLFPAQELRHIFSAASEDLIFLLESLLA 273
G P +++W +K + + Y L E +H S+ LL+ LL
Sbjct: 260 GFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYME-KHKVKPDSK-AFHLLQKLLT 317
Query: 274 LYPPNRCDCTQALQMAYFSSKPAPS----VGPKLPMPSNISKLEVEKPSLK 320
+ P R QA+Q YF P P+ G ++P P L E+P K
Sbjct: 318 MDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKR-EFLTEEEPDDK 367
>BC069634-1|AAH69634.1| 463|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 463
Score = 171 bits (416), Expect = 3e-42
Identities = 132/351 (37%), Positives = 178/351 (50%), Gaps = 54/351 (15%)
Query: 14 LGEGQFATVYKAK--DAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLI 71
+G G + VYKAK D K DK A+K+I+ G+ GI+ +A REI LL+EL+H N+I
Sbjct: 27 VGRGTYGHVYKAKRKDGKDDKDYALKQIE-GT------GISMSACREIALLRELKHPNVI 79
Query: 72 GLLDVFGQKSN--VSLVFDFMDTDLEIIIK--------DNTIVLTPANVKAYMIMTLKGL 121
L VF ++ V L+FD+ + DL IIK + L VK+ + L G+
Sbjct: 80 SLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGI 139
Query: 122 EYLHQNWILHRDLKPNTLLINREGI----LKIGDFGLAKAFGSPTRINTHQ---VVTRWY 174
YLH NW+LHRDLKP +L+ EG +KI D G A+ F SP + VVT WY
Sbjct: 140 HYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWY 199
Query: 175 RAPELLFGARQYGTGVDMWAVGCILAELLLRVP-FLPGESDL--------DQLSRIFQVF 225
RAPELL GAR Y +D+WA+GCI AELL P F + D+ DQL RIF V
Sbjct: 200 RAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVM 259
Query: 226 GTPTEENWPGMKTLTD------------YVQFKLFPAQELRHIFSAASEDLIFLLESLLA 273
G P +++W +K + + Y L E +H S+ LL+ LL
Sbjct: 260 GFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYME-KHKVKPDSK-AFHLLQKLLT 317
Query: 274 LYPPNRCDCTQALQMAYFSSKPAPS----VGPKLPMPSNISKLEVEKPSLK 320
+ P R QA+Q YF P P+ G ++P P L E+P K
Sbjct: 318 MDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKR-EFLTEEEPDDK 367
>BC027933-1|AAH27933.1| 364|Homo sapiens mitogen-activated protein
kinase 11 protein.
Length = 364
Score = 171 bits (416), Expect = 3e-42
Identities = 116/299 (38%), Positives = 160/299 (53%), Gaps = 19/299 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGIN-RTALREIKLLQELQHINLIG 72
+G G + +V A DA+ + VAVKK+ SR Q I+ R RE++LL+ L+H N+IG
Sbjct: 30 VGSGAYGSVCSAYDARLRQKVAVKKL---SR-PFQSLIHARRTYRELRLLKHLKHENVIG 85
Query: 73 LLDVFGQK------SNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
LLDVF S V LV M DL I+K L+ +V+ + L+GL+Y+H
Sbjct: 86 LLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQA--LSDEHVQFLVYQLLRGLKYIHS 143
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
I+HRDLKP+ + +N + L+I DFGLA+ T V TRWYRAPE++ Y
Sbjct: 144 AGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM---TGYVATRWYRAPEIMLNWMHY 200
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT--LTDYVQ 244
VD+W+VGCI+AELL PG +DQL RI +V GTP+ E + + Y+Q
Sbjct: 201 NQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQ 260
Query: 245 -FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPK 302
P ++L IF A+ I LL +L L R +AL AYFS P P+
Sbjct: 261 SLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPE 319
>AL590108-1|CAH72300.1| 464|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 464
Score = 171 bits (416), Expect = 3e-42
Identities = 132/351 (37%), Positives = 178/351 (50%), Gaps = 54/351 (15%)
Query: 14 LGEGQFATVYKAK--DAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLI 71
+G G + VYKAK D K DK A+K+I+ G+ GI+ +A REI LL+EL+H N+I
Sbjct: 27 VGRGTYGHVYKAKRKDGKDDKDYALKQIE-GT------GISMSACREIALLRELKHPNVI 79
Query: 72 GLLDVFGQKSN--VSLVFDFMDTDLEIIIK--------DNTIVLTPANVKAYMIMTLKGL 121
L VF ++ V L+FD+ + DL IIK + L VK+ + L G+
Sbjct: 80 SLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGI 139
Query: 122 EYLHQNWILHRDLKPNTLLINREGI----LKIGDFGLAKAFGSPTRINTHQ---VVTRWY 174
YLH NW+LHRDLKP +L+ EG +KI D G A+ F SP + VVT WY
Sbjct: 140 HYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWY 199
Query: 175 RAPELLFGARQYGTGVDMWAVGCILAELLLRVP-FLPGESDL--------DQLSRIFQVF 225
RAPELL GAR Y +D+WA+GCI AELL P F + D+ DQL RIF V
Sbjct: 200 RAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVM 259
Query: 226 GTPTEENWPGMKTLTD------------YVQFKLFPAQELRHIFSAASEDLIFLLESLLA 273
G P +++W +K + + Y L E +H S+ LL+ LL
Sbjct: 260 GFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYME-KHKVKPDSK-AFHLLQKLLT 317
Query: 274 LYPPNRCDCTQALQMAYFSSKPAPS----VGPKLPMPSNISKLEVEKPSLK 320
+ P R QA+Q YF P P+ G ++P P L E+P K
Sbjct: 318 MDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKR-EFLTEEEPDDK 367
>AL159159-1|CAI16960.1| 464|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 464
Score = 171 bits (416), Expect = 3e-42
Identities = 132/351 (37%), Positives = 178/351 (50%), Gaps = 54/351 (15%)
Query: 14 LGEGQFATVYKAK--DAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLI 71
+G G + VYKAK D K DK A+K+I+ G+ GI+ +A REI LL+EL+H N+I
Sbjct: 27 VGRGTYGHVYKAKRKDGKDDKDYALKQIE-GT------GISMSACREIALLRELKHPNVI 79
Query: 72 GLLDVFGQKSN--VSLVFDFMDTDLEIIIK--------DNTIVLTPANVKAYMIMTLKGL 121
L VF ++ V L+FD+ + DL IIK + L VK+ + L G+
Sbjct: 80 SLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGI 139
Query: 122 EYLHQNWILHRDLKPNTLLINREGI----LKIGDFGLAKAFGSPTRINTHQ---VVTRWY 174
YLH NW+LHRDLKP +L+ EG +KI D G A+ F SP + VVT WY
Sbjct: 140 HYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWY 199
Query: 175 RAPELLFGARQYGTGVDMWAVGCILAELLLRVP-FLPGESDL--------DQLSRIFQVF 225
RAPELL GAR Y +D+WA+GCI AELL P F + D+ DQL RIF V
Sbjct: 200 RAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVM 259
Query: 226 GTPTEENWPGMKTLTD------------YVQFKLFPAQELRHIFSAASEDLIFLLESLLA 273
G P +++W +K + + Y L E +H S+ LL+ LL
Sbjct: 260 GFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYME-KHKVKPDSK-AFHLLQKLLT 317
Query: 274 LYPPNRCDCTQALQMAYFSSKPAPS----VGPKLPMPSNISKLEVEKPSLK 320
+ P R QA+Q YF P P+ G ++P P L E+P K
Sbjct: 318 MDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKR-EFLTEEEPDDK 367
>AL022328-13|CAB51539.1| 364|Homo sapiens mitogen-activated protein
kinase 11 protein.
Length = 364
Score = 171 bits (416), Expect = 3e-42
Identities = 116/299 (38%), Positives = 160/299 (53%), Gaps = 19/299 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGIN-RTALREIKLLQELQHINLIG 72
+G G + +V A DA+ + VAVKK+ SR Q I+ R RE++LL+ L+H N+IG
Sbjct: 30 VGSGAYGSVCSAYDARLRQKVAVKKL---SR-PFQSLIHARRTYRELRLLKHLKHENVIG 85
Query: 73 LLDVFGQK------SNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
LLDVF S V LV M DL I+K L+ +V+ + L+GL+Y+H
Sbjct: 86 LLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQA--LSDEHVQFLVYQLLRGLKYIHS 143
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
I+HRDLKP+ + +N + L+I DFGLA+ T V TRWYRAPE++ Y
Sbjct: 144 AGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM---TGYVATRWYRAPEIMLNWMHY 200
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT--LTDYVQ 244
VD+W+VGCI+AELL PG +DQL RI +V GTP+ E + + Y+Q
Sbjct: 201 NQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQ 260
Query: 245 -FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPK 302
P ++L IF A+ I LL +L L R +AL AYFS P P+
Sbjct: 261 SLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPE 319
>AF031135-1|AAC12714.1| 364|Homo sapiens p38beta2 MAP kinase
protein.
Length = 364
Score = 171 bits (416), Expect = 3e-42
Identities = 116/299 (38%), Positives = 160/299 (53%), Gaps = 19/299 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGIN-RTALREIKLLQELQHINLIG 72
+G G + +V A DA+ + VAVKK+ SR Q I+ R RE++LL+ L+H N+IG
Sbjct: 30 VGSGAYGSVCSAYDARLRQKVAVKKL---SR-PFQSLIHARRTYRELRLLKHLKHENVIG 85
Query: 73 LLDVFGQK------SNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
LLDVF S V LV M DL I+K L+ +V+ + L+GL+Y+H
Sbjct: 86 LLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQA--LSDEHVQFLVYQLLRGLKYIHS 143
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
I+HRDLKP+ + +N + L+I DFGLA+ T V TRWYRAPE++ Y
Sbjct: 144 AGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM---TGYVATRWYRAPEIMLNWMHY 200
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT--LTDYVQ 244
VD+W+VGCI+AELL PG +DQL RI +V GTP+ E + + Y+Q
Sbjct: 201 NQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQ 260
Query: 245 -FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPK 302
P ++L IF A+ I LL +L L R +AL AYFS P P+
Sbjct: 261 SLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPE 319
>AF001174-1|AAC51373.1| 364|Homo sapiens p38beta2 MAP kinase
protein.
Length = 364
Score = 171 bits (416), Expect = 3e-42
Identities = 116/299 (38%), Positives = 160/299 (53%), Gaps = 19/299 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGIN-RTALREIKLLQELQHINLIG 72
+G G + +V A DA+ + VAVKK+ SR Q I+ R RE++LL+ L+H N+IG
Sbjct: 30 VGSGAYGSVCSAYDARLRQKVAVKKL---SR-PFQSLIHARRTYRELRLLKHLKHENVIG 85
Query: 73 LLDVFGQK------SNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
LLDVF S V LV M DL I+K L+ +V+ + L+GL+Y+H
Sbjct: 86 LLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQA--LSDEHVQFLVYQLLRGLKYIHS 143
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
I+HRDLKP+ + +N + L+I DFGLA+ T V TRWYRAPE++ Y
Sbjct: 144 AGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM---TGYVATRWYRAPEIMLNWMHY 200
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT--LTDYVQ 244
VD+W+VGCI+AELL PG +DQL RI +V GTP+ E + + Y+Q
Sbjct: 201 NQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQ 260
Query: 245 -FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPK 302
P ++L IF A+ I LL +L L R +AL AYFS P P+
Sbjct: 261 SLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPE 319
>AF001008-1|AAC51250.1| 364|Homo sapiens p38Beta2 MAP Kinase
protein.
Length = 364
Score = 171 bits (416), Expect = 3e-42
Identities = 116/299 (38%), Positives = 160/299 (53%), Gaps = 19/299 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGIN-RTALREIKLLQELQHINLIG 72
+G G + +V A DA+ + VAVKK+ SR Q I+ R RE++LL+ L+H N+IG
Sbjct: 30 VGSGAYGSVCSAYDARLRQKVAVKKL---SR-PFQSLIHARRTYRELRLLKHLKHENVIG 85
Query: 73 LLDVFGQK------SNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQ 126
LLDVF S V LV M DL I+K L+ +V+ + L+GL+Y+H
Sbjct: 86 LLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQA--LSDEHVQFLVYQLLRGLKYIHS 143
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQY 186
I+HRDLKP+ + +N + L+I DFGLA+ T V TRWYRAPE++ Y
Sbjct: 144 AGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM---TGYVATRWYRAPEIMLNWMHY 200
Query: 187 GTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT--LTDYVQ 244
VD+W+VGCI+AELL PG +DQL RI +V GTP+ E + + Y+Q
Sbjct: 201 NQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQ 260
Query: 245 -FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPK 302
P ++L IF A+ I LL +L L R +AL AYFS P P+
Sbjct: 261 SLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPE 319
>Z11696-1|CAA77754.1| 355|Homo sapiens 44kDa protein kinase
protein.
Length = 355
Score = 169 bits (412), Expect = 9e-42
Identities = 107/311 (34%), Positives = 163/311 (52%), Gaps = 17/311 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY ++ ++GEG + V A D VA+KKI S E Q RT LREI++L +
Sbjct: 17 RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI---SPFEHQTYCQRT-LREIQILLRFR 72
Query: 67 HINLIGLLDVFGQKS-----NVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
H N+IG+ D+ + +V +V D M+TDL ++K L+ ++ ++ L+GL
Sbjct: 73 HENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQ--LSNDHICYFLYQILRGL 130
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSP---TRINTHQVVTRWYRAPE 178
+Y+H +LHRDLKP+ LLIN LKI DFGLA+ T T V TRWYRAPE
Sbjct: 131 KYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPE 190
Query: 179 LLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT 238
++ ++ Y +D+W+VGCILAE+L P PG+ LDQL+ I + G+P++E+ +
Sbjct: 191 IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN 250
Query: 239 LTDYVQFKLFPAQ---ELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKP 295
+ + P++ +F + + LL+ +L P R +AL Y
Sbjct: 251 MKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYY 310
Query: 296 APSVGPKLPMP 306
P+ P P
Sbjct: 311 DPTDEPVAEEP 321
>M84490-1|AAA36142.1| 366|Homo sapiens kinase 1 protein.
Length = 366
Score = 169 bits (412), Expect = 9e-42
Identities = 107/311 (34%), Positives = 163/311 (52%), Gaps = 17/311 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY ++ ++GEG + V A D VA+KKI S E Q RT LREI++L +
Sbjct: 28 RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI---SPFEHQTYCQRT-LREIQILLRFR 83
Query: 67 HINLIGLLDVFGQKS-----NVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
H N+IG+ D+ + +V +V D M+TDL ++K L+ ++ ++ L+GL
Sbjct: 84 HENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQ--LSNDHICYFLYQILRGL 141
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSP---TRINTHQVVTRWYRAPE 178
+Y+H +LHRDLKP+ LLIN LKI DFGLA+ T T V TRWYRAPE
Sbjct: 142 KYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPE 201
Query: 179 LLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT 238
++ ++ Y +D+W+VGCILAE+L P PG+ LDQL+ I + G+P++E+ +
Sbjct: 202 IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN 261
Query: 239 LTDYVQFKLFPAQ---ELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKP 295
+ + P++ +F + + LL+ +L P R +AL Y
Sbjct: 262 MKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYY 321
Query: 296 APSVGPKLPMP 306
P+ P P
Sbjct: 322 DPTDEPVAEEP 332
>BC013992-1|AAH13992.1| 379|Homo sapiens mitogen-activated protein
kinase 3 protein.
Length = 379
Score = 169 bits (412), Expect = 9e-42
Identities = 107/311 (34%), Positives = 163/311 (52%), Gaps = 17/311 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY ++ ++GEG + V A D VA+KKI S E Q RT LREI++L +
Sbjct: 41 RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI---SPFEHQTYCQRT-LREIQILLRFR 96
Query: 67 HINLIGLLDVFGQKS-----NVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
H N+IG+ D+ + +V +V D M+TDL ++K L+ ++ ++ L+GL
Sbjct: 97 HENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQ--LSNDHICYFLYQILRGL 154
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSP---TRINTHQVVTRWYRAPE 178
+Y+H +LHRDLKP+ LLIN LKI DFGLA+ T T V TRWYRAPE
Sbjct: 155 KYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPE 214
Query: 179 LLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT 238
++ ++ Y +D+W+VGCILAE+L P PG+ LDQL+ I + G+P++E+ +
Sbjct: 215 IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN 274
Query: 239 LTDYVQFKLFPAQ---ELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKP 295
+ + P++ +F + + LL+ +L P R +AL Y
Sbjct: 275 MKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYY 334
Query: 296 APSVGPKLPMP 306
P+ P P
Sbjct: 335 DPTDEPVAEEP 345
>L35263-1|AAA57455.1| 360|Homo sapiens CSaids binding protein
protein.
Length = 360
Score = 169 bits (410), Expect = 2e-41
Identities = 112/304 (36%), Positives = 159/304 (52%), Gaps = 17/304 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY+ + +G G + +V A D KT VAVKK+ ++ RT RE++LL+ ++
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLS--RPFQSIIHAKRT-YRELRLLKHMK 79
Query: 67 HINLIGLLDVFG------QKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKG 120
H N+IGLLDVF + ++V LV M DL I+K LT +V+ + L+G
Sbjct: 80 HENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQK--LTDDHVQFLIYQILRG 137
Query: 121 LEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELL 180
L+Y+H I+HRDLKP+ L +N + LKI DFGLA+ T V TRWYRAPE++
Sbjct: 138 LKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEM---TGYVATRWYRAPEIM 194
Query: 181 FGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEE--NWPGMKT 238
Y VD+W+VGCI+AELL PG ++QL +I ++ GTP N
Sbjct: 195 LNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPAYLINRMPSHE 254
Query: 239 LTDYVQ-FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAP 297
+Y+Q P ++F A+ + LLE +L L R QAL AYF+ P
Sbjct: 255 ARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDP 314
Query: 298 SVGP 301
P
Sbjct: 315 DDEP 318
>X60188-1|CAA42744.1| 379|Homo sapiens protein serine/threonine
kinase protein.
Length = 379
Score = 167 bits (406), Expect = 5e-41
Identities = 106/311 (34%), Positives = 162/311 (52%), Gaps = 17/311 (5%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY ++ ++GEG + V A D VA+KKI S E Q RT LREI++L +
Sbjct: 41 RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI---SPFEHQTYCQRT-LREIQILLRFR 96
Query: 67 HINLIGLLDVFGQKS-----NVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
H N+IG+ D+ + +V +V D M+TDL ++K L+ ++ ++ L+GL
Sbjct: 97 HENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQ--LSNDHICYFLYQILRGL 154
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSP---TRINTHQVVTRWYRAPE 178
+Y+H +LHRDLKP+ LL N LKI DFGLA+ T T V TRWYRAPE
Sbjct: 155 KYIHSANVLHRDLKPSNLLSNTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPE 214
Query: 179 LLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT 238
++ ++ Y +D+W+VGCILAE+L P PG+ LDQL+ I + G+P++E+ +
Sbjct: 215 IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN 274
Query: 239 LTDYVQFKLFPAQ---ELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKP 295
+ + P++ +F + + LL+ +L P R +AL Y
Sbjct: 275 MKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYY 334
Query: 296 APSVGPKLPMP 306
P+ P P
Sbjct: 335 DPTDEPVAEEP 345
>Z95152-3|CAB08438.1| 365|Homo sapiens mitogen-activated protein
kinase 13 protein.
Length = 365
Score = 167 bits (405), Expect = 6e-41
Identities = 113/312 (36%), Positives = 163/312 (52%), Gaps = 19/312 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLIGL 73
+G G + +V A D ++ + VA+KK+ SR + + A RE+ LL+ +QH N+IGL
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKL---SRPFQSEIFAKRAYRELLLLKHMQHENVIGL 87
Query: 74 LDVFGQKSNVS------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
LDVF S++ LV FM TDL+ I+ + + ++ + LKGL+Y+H
Sbjct: 88 LDVFTPASSLRNFYDFYLVMPFMQTDLQKIMG---MEFSEEKIQYLVYQMLKGLKYIHSA 144
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
++HRDLKP L +N + LKI DFGLA+ + T VVTRWYRAPE++ Y
Sbjct: 145 GVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM---TGYVVTRWYRAPEVILSWMHYN 201
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGM--KTLTDYVQ- 244
VD+W+VGCI+AE+L G+ LDQL++I +V G P E + K Y+Q
Sbjct: 202 QTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQS 261
Query: 245 FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLP 304
P ++ +F AS LLE +L L R QAL +F P +
Sbjct: 262 LPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQ 321
Query: 305 MPSNISKLEVEK 316
P + S LE EK
Sbjct: 322 QPFDDS-LEHEK 332
>Y10488-1|CAA71512.1| 365|Homo sapiens stress-activated protein
kinase-4 protein.
Length = 365
Score = 167 bits (405), Expect = 6e-41
Identities = 113/312 (36%), Positives = 163/312 (52%), Gaps = 19/312 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLIGL 73
+G G + +V A D ++ + VA+KK+ SR + + A RE+ LL+ +QH N+IGL
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKL---SRPFQSEIFAKRAYRELLLLKHMQHENVIGL 87
Query: 74 LDVFGQKSNVS------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
LDVF S++ LV FM TDL+ I+ + + ++ + LKGL+Y+H
Sbjct: 88 LDVFTPASSLRNFYDFYLVMPFMQTDLQKIMG---MEFSEEKIQYLVYQMLKGLKYIHSA 144
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
++HRDLKP L +N + LKI DFGLA+ + T VVTRWYRAPE++ Y
Sbjct: 145 GVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM---TGYVVTRWYRAPEVILSWMHYN 201
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGM--KTLTDYVQ- 244
VD+W+VGCI+AE+L G+ LDQL++I +V G P E + K Y+Q
Sbjct: 202 QTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQS 261
Query: 245 FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLP 304
P ++ +F AS LLE +L L R QAL +F P +
Sbjct: 262 LPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQ 321
Query: 305 MPSNISKLEVEK 316
P + S LE EK
Sbjct: 322 QPFDDS-LEHEK 332
>U93232-1|AAB87639.1| 365|Homo sapiens MAP kinase p38delta protein.
Length = 365
Score = 167 bits (405), Expect = 6e-41
Identities = 113/312 (36%), Positives = 163/312 (52%), Gaps = 19/312 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLIGL 73
+G G + +V A D ++ + VA+KK+ SR + + A RE+ LL+ +QH N+IGL
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKL---SRPFQSEIFAKRAYRELLLLKHMQHENVIGL 87
Query: 74 LDVFGQKSNVS------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
LDVF S++ LV FM TDL+ I+ + + ++ + LKGL+Y+H
Sbjct: 88 LDVFTPASSLRNFYDFYLVMPFMQTDLQKIMG---MEFSEEKIQYLVYQMLKGLKYIHSA 144
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
++HRDLKP L +N + LKI DFGLA+ + T VVTRWYRAPE++ Y
Sbjct: 145 GVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM---TGYVVTRWYRAPEVILSWMHYN 201
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGM--KTLTDYVQ- 244
VD+W+VGCI+AE+L G+ LDQL++I +V G P E + K Y+Q
Sbjct: 202 QTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQS 261
Query: 245 FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLP 304
P ++ +F AS LLE +L L R QAL +F P +
Sbjct: 262 LPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQ 321
Query: 305 MPSNISKLEVEK 316
P + S LE EK
Sbjct: 322 QPFDDS-LEHEK 332
>CR541687-1|CAG46488.1| 365|Homo sapiens MAPK13 protein.
Length = 365
Score = 167 bits (405), Expect = 6e-41
Identities = 113/312 (36%), Positives = 163/312 (52%), Gaps = 19/312 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLIGL 73
+G G + +V A D ++ + VA+KK+ SR + + A RE+ LL+ +QH N+IGL
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKL---SRPFQSEIFAKRAYRELLLLKHMQHENVIGL 87
Query: 74 LDVFGQKSNVS------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
LDVF S++ LV FM TDL+ I+ + + ++ + LKGL+Y+H
Sbjct: 88 LDVFTPASSLRNFYDFYLVMPFMQTDLQKIMG---MEFSEEKIQYLVYQMLKGLKYIHSA 144
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
++HRDLKP L +N + LKI DFGLA+ + T VVTRWYRAPE++ Y
Sbjct: 145 GVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM---TGYVVTRWYRAPEVILSWMHYN 201
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGM--KTLTDYVQ- 244
VD+W+VGCI+AE+L G+ LDQL++I +V G P E + K Y+Q
Sbjct: 202 QTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQS 261
Query: 245 FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLP 304
P ++ +F AS LLE +L L R QAL +F P +
Sbjct: 262 LPQTPRKDFTQLFPRASPQAADLLEKMLELGVDKRLTAAQALTHPFFEPFRDPEEETEAQ 321
Query: 305 MPSNISKLEVEK 316
P + S LE EK
Sbjct: 322 QPFDDS-LEHEK 332
>CR536490-1|CAG38729.1| 365|Homo sapiens MAPK13 protein.
Length = 365
Score = 167 bits (405), Expect = 6e-41
Identities = 113/312 (36%), Positives = 163/312 (52%), Gaps = 19/312 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLIGL 73
+G G + +V A D ++ + VA+KK+ SR + + A RE+ LL+ +QH N+IGL
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKL---SRPFQSEIFAKRAYRELLLLKHMQHENVIGL 87
Query: 74 LDVFGQKSNVS------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
LDVF S++ LV FM TDL+ I+ + + ++ + LKGL+Y+H
Sbjct: 88 LDVFTPASSLRNFYDFYLVMPFMQTDLQKIMG---MEFSEEKIQYLVYQMLKGLKYIHSA 144
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
++HRDLKP L +N + LKI DFGLA+ + T VVTRWYRAPE++ Y
Sbjct: 145 GVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM---TGYVVTRWYRAPEVILSWMHYN 201
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGM--KTLTDYVQ- 244
VD+W+VGCI+AE+L G+ LDQL++I +V G P E + K Y+Q
Sbjct: 202 QTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQS 261
Query: 245 FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLP 304
P ++ +F AS LLE +L L R QAL +F P +
Sbjct: 262 LPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQ 321
Query: 305 MPSNISKLEVEK 316
P + S LE EK
Sbjct: 322 QPFDDS-LEHEK 332
>BT007221-1|AAP35885.1| 365|Homo sapiens mitogen-activated protein
kinase 13 protein.
Length = 365
Score = 167 bits (405), Expect = 6e-41
Identities = 113/312 (36%), Positives = 163/312 (52%), Gaps = 19/312 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLIGL 73
+G G + +V A D ++ + VA+KK+ SR + + A RE+ LL+ +QH N+IGL
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKL---SRPFQSEIFAKRAYRELLLLKHMQHENVIGL 87
Query: 74 LDVFGQKSNVS------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
LDVF S++ LV FM TDL+ I+ + + ++ + LKGL+Y+H
Sbjct: 88 LDVFTPASSLRNFYDFYLVMPFMQTDLQKIMG---MEFSEEKIQYLVYQMLKGLKYIHSA 144
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
++HRDLKP L +N + LKI DFGLA+ + T VVTRWYRAPE++ Y
Sbjct: 145 GVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM---TGYVVTRWYRAPEVILSWMHYN 201
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGM--KTLTDYVQ- 244
VD+W+VGCI+AE+L G+ LDQL++I +V G P E + K Y+Q
Sbjct: 202 QTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQS 261
Query: 245 FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLP 304
P ++ +F AS LLE +L L R QAL +F P +
Sbjct: 262 LPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQ 321
Query: 305 MPSNISKLEVEK 316
P + S LE EK
Sbjct: 322 QPFDDS-LEHEK 332
>BC004428-1|AAH04428.1| 365|Homo sapiens mitogen-activated protein
kinase 13 protein.
Length = 365
Score = 167 bits (405), Expect = 6e-41
Identities = 113/312 (36%), Positives = 163/312 (52%), Gaps = 19/312 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLIGL 73
+G G + +V A D ++ + VA+KK+ SR + + A RE+ LL+ +QH N+IGL
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKL---SRPFQSEIFAKRAYRELLLLKHMQHENVIGL 87
Query: 74 LDVFGQKSNVS------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
LDVF S++ LV FM TDL+ I+ + + ++ + LKGL+Y+H
Sbjct: 88 LDVFTPASSLRNFYDFYLVMPFMQTDLQKIMG---MEFSEEKIQYLVYQMLKGLKYIHSA 144
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
++HRDLKP L +N + LKI DFGLA+ + T VVTRWYRAPE++ Y
Sbjct: 145 GVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM---TGYVVTRWYRAPEVILSWMHYN 201
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGM--KTLTDYVQ- 244
VD+W+VGCI+AE+L G+ LDQL++I +V G P E + K Y+Q
Sbjct: 202 QTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQS 261
Query: 245 FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLP 304
P ++ +F AS LLE +L L R QAL +F P +
Sbjct: 262 LPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQ 321
Query: 305 MPSNISKLEVEK 316
P + S LE EK
Sbjct: 322 QPFDDS-LEHEK 332
>BC001641-1|AAH01641.1| 365|Homo sapiens mitogen-activated protein
kinase 13 protein.
Length = 365
Score = 167 bits (405), Expect = 6e-41
Identities = 113/312 (36%), Positives = 163/312 (52%), Gaps = 19/312 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLIGL 73
+G G + +V A D ++ + VA+KK+ SR + + A RE+ LL+ +QH N+IGL
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKL---SRPFQSEIFAKRAYRELLLLKHMQHENVIGL 87
Query: 74 LDVFGQKSNVS------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
LDVF S++ LV FM TDL+ I+ + + ++ + LKGL+Y+H
Sbjct: 88 LDVFTPASSLRNFYDFYLVMPFMQTDLQKIMG---MEFSEEKIQYLVYQMLKGLKYIHSA 144
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
++HRDLKP L +N + LKI DFGLA+ + T VVTRWYRAPE++ Y
Sbjct: 145 GVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM---TGYVVTRWYRAPEVILSWMHYN 201
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGM--KTLTDYVQ- 244
VD+W+VGCI+AE+L G+ LDQL++I +V G P E + K Y+Q
Sbjct: 202 QTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQS 261
Query: 245 FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLP 304
P ++ +F AS LLE +L L R QAL +F P +
Sbjct: 262 LPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQ 321
Query: 305 MPSNISKLEVEK 316
P + S LE EK
Sbjct: 322 QPFDDS-LEHEK 332
>BC000433-1|AAH00433.1| 365|Homo sapiens mitogen-activated protein
kinase 13 protein.
Length = 365
Score = 167 bits (405), Expect = 6e-41
Identities = 113/312 (36%), Positives = 163/312 (52%), Gaps = 19/312 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLIGL 73
+G G + +V A D ++ + VA+KK+ SR + + A RE+ LL+ +QH N+IGL
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKL---SRPFQSEIFAKRAYRELLLLKHMQHENVIGL 87
Query: 74 LDVFGQKSNVS------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
LDVF S++ LV FM TDL+ I+ + + ++ + LKGL+Y+H
Sbjct: 88 LDVFTPASSLRNFYDFYLVMPFMQTDLQKIMG---MEFSEEKIQYLVYQMLKGLKYIHSA 144
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
++HRDLKP L +N + LKI DFGLA+ + T VVTRWYRAPE++ Y
Sbjct: 145 GVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM---TGYVVTRWYRAPEVILSWMHYN 201
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGM--KTLTDYVQ- 244
VD+W+VGCI+AE+L G+ LDQL++I +V G P E + K Y+Q
Sbjct: 202 QTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQS 261
Query: 245 FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLP 304
P ++ +F AS LLE +L L R QAL +F P +
Sbjct: 262 LPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQ 321
Query: 305 MPSNISKLEVEK 316
P + S LE EK
Sbjct: 322 QPFDDS-LEHEK 332
>AF100546-1|AAF36772.1| 365|Homo sapiens stress-activated protein
kinase 4 protein.
Length = 365
Score = 167 bits (405), Expect = 6e-41
Identities = 113/312 (36%), Positives = 163/312 (52%), Gaps = 19/312 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLIGL 73
+G G + +V A D ++ + VA+KK+ SR + + A RE+ LL+ +QH N+IGL
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKL---SRPFQSEIFAKRAYRELLLLKHMQHENVIGL 87
Query: 74 LDVFGQKSNVS------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
LDVF S++ LV FM TDL+ I+ + + ++ + LKGL+Y+H
Sbjct: 88 LDVFTPASSLRNFYDFYLVMPFMQTDLQKIMG---MEFSEEKIQYLVYQMLKGLKYIHSA 144
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
++HRDLKP L +N + LKI DFGLA+ + T VVTRWYRAPE++ Y
Sbjct: 145 GVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM---TGYVVTRWYRAPEVILSWMHYN 201
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGM--KTLTDYVQ- 244
VD+W+VGCI+AE+L G+ LDQL++I +V G P E + K Y+Q
Sbjct: 202 QTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQS 261
Query: 245 FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLP 304
P ++ +F AS LLE +L L R QAL +F P +
Sbjct: 262 LPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQ 321
Query: 305 MPSNISKLEVEK 316
P + S LE EK
Sbjct: 322 QPFDDS-LEHEK 332
>AY033607-1|AAK52329.1| 357|Homo sapiens extracellular
signal-related kinase 1b protein.
Length = 357
Score = 166 bits (404), Expect = 9e-41
Identities = 106/307 (34%), Positives = 161/307 (52%), Gaps = 19/307 (6%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY ++ ++GEG + V A D VA+KKI S E Q RT LREI++L +
Sbjct: 41 RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI---SPFEHQTYCQRT-LREIQILLRFR 96
Query: 67 HINLIGLLDVFGQKS-----NVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
H N+IG+ D+ + +V +V D M+TDL ++K L+ ++ ++ L+GL
Sbjct: 97 HENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQ--LSNDHICYFLYQILRGL 154
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSP---TRINTHQVVTRWYRAPE 178
+Y+H +LHRDLKP+ LL N LKI DFGLA+ T T V TRWYRAPE
Sbjct: 155 KYIHSANVLHRDLKPSNLLSNTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPE 214
Query: 179 LLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT 238
++ ++ Y +D+W+VGCILAE+L P PG+ LDQL+ I + G+P++E+ +
Sbjct: 215 IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN 274
Query: 239 LTDYVQFKLFPAQ---ELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS-- 293
+ + P++ +F + + LL+ +L P R +AL Y
Sbjct: 275 MKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYY 334
Query: 294 KPAPSVG 300
P VG
Sbjct: 335 DPTDEVG 341
>AF092535-1|AAD23377.1| 365|Homo sapiens mitogen-activated protein
kinase p38delta protein.
Length = 365
Score = 166 bits (404), Expect = 9e-41
Identities = 113/312 (36%), Positives = 163/312 (52%), Gaps = 19/312 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLIGL 73
+G G + +V A D ++ + VA+KK+ SR + + A RE+ LL+ +QH N+IGL
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKKL---SRPFQSEIFAKRAYRELLLLKHMQHENVIGL 87
Query: 74 LDVFGQKSNVS------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
LDVF S++ LV FM TDL+ I+ + + ++ + LKGL+Y+H
Sbjct: 88 LDVFTPASSLRNFYDFYLVMPFMQTDLQKIMG---MEFSEEKIQYLVYQMLKGLKYIHSA 144
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
++HRDLKP L +N + LKI DFGLA+ + T VVTRWYRAPE++ Y
Sbjct: 145 GVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM---TGYVVTRWYRAPEVILSWMHYN 201
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGM--KTLTDYVQ- 244
VD+W+VGCI+AE+L G+ LDQL++I +V G P E + K Y+Q
Sbjct: 202 QTVDIWSVGCIMAEMLTGKTLFRGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQS 261
Query: 245 FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLP 304
P ++ +F AS LLE +L L R QAL +F P +
Sbjct: 262 LPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQ 321
Query: 305 MPSNISKLEVEK 316
P + S LE EK
Sbjct: 322 QPFDDS-LEHEK 332
>U53442-1|AAB05036.1| 372|Homo sapiens p38Beta MAP kinase protein.
Length = 372
Score = 165 bits (402), Expect = 1e-40
Identities = 115/305 (37%), Positives = 159/305 (52%), Gaps = 23/305 (7%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGIN-RTALREIKLLQELQHINLIG 72
+G G + +V A DA+ + VAVKK+ SR Q I+ R RE++LL+ L+H N+IG
Sbjct: 30 VGSGAYGSVCSAYDARLRQKVAVKKL---SR-PFQSLIHARRTYRELRLLKHLKHENVIG 85
Query: 73 LLDVFGQK------SNVSLVFDFMDTDLEIIIK------DNTIVLTPANVKAYMIMTLKG 120
LLDVF S V LV M DL I+K + +V+ + L+G
Sbjct: 86 LLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQAGAHQGARLALDEHVQFLVYQLLRG 145
Query: 121 LEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELL 180
L+Y+H I+HRDLKP+ + +N + L+I DFGLA+ T V TRWYRAPE++
Sbjct: 146 LKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM---TGYVATRWYRAPEIM 202
Query: 181 FGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT-- 238
Y VD+W+VGCI+AELL PG +DQL RI +V GTP+ E + +
Sbjct: 203 LNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEH 262
Query: 239 LTDYVQ-FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAP 297
Y+Q P ++L IF A+ I LL +L L R +AL AYFS P
Sbjct: 263 ARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDP 322
Query: 298 SVGPK 302
P+
Sbjct: 323 EDEPE 327
>AL353572-5|CAM17658.1| 338|Homo sapiens cell cycle related kinase
protein.
Length = 338
Score = 165 bits (401), Expect = 2e-40
Identities = 116/314 (36%), Positives = 163/314 (51%), Gaps = 43/314 (13%)
Query: 14 LGEGQFATVYKAKDAK-------------TDKIVAVKKIKIGSRLEAQDGINRTALREIK 60
+GEG V+KAK + T +IVA+KK+ + RLE DG ALREIK
Sbjct: 10 IGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVAL-RRLE--DGFPNQALREIK 66
Query: 61 LLQELQHIN-LIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLK 119
LQE++ ++ L VF L F+FM +DL +++ L A VK+Y+ M LK
Sbjct: 67 ALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLK 126
Query: 120 GLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFG-SPTRINTHQVVTRWYRAPE 178
G+ + H N I+HRDLKP LLI+ G LKI DFGLA+ F +R+ THQV TR
Sbjct: 127 GVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR------ 180
Query: 179 LLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKT 238
+VGCI+ ELL P PG++D++QL + ++ GTP + WP +
Sbjct: 181 ---------------SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTE 225
Query: 239 LTDY--VQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPN-RCDCTQALQMAYFSSKP 295
L DY + FK L + S + LL L LYPP+ R ++AL YF + P
Sbjct: 226 LPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFL-LYPPHQRIAASKALLHQYFFTAP 284
Query: 296 APSVGPKLPMPSNI 309
P+ +LP+P +
Sbjct: 285 LPAHPSELPIPQRL 298
>BC002655-1|AAH02655.1| 275|Homo sapiens CCRK protein protein.
Length = 275
Score = 165 bits (400), Expect = 3e-40
Identities = 106/270 (39%), Positives = 147/270 (54%), Gaps = 29/270 (10%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHIN-LIG 72
+GEG V+KAK +T +IVA+KK+ + RLE DG ALREIK LQE++ ++
Sbjct: 10 IGEGAHGIVFKAKHVETGEIVALKKVAL-RRLE--DGFPNQALREIKALQEMEDNQYVVQ 66
Query: 73 LLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQNWILHR 132
L VF L F+FM +DL +++ L A VK+Y+ M LKG+ + H N I+HR
Sbjct: 67 LKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHANNIVHR 126
Query: 133 DLKPNTLLINREGILKIGDFGLAKAFG-SPTRINTHQVVTRWYRAPELLFGARQYGTGVD 191
DLKP LLI+ G LKI DFGLA+ F +R+ THQV TR
Sbjct: 127 DLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR------------------- 167
Query: 192 MWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDY--VQFKLFP 249
+VGCI+ ELL P PG++D++QL + ++ GTP + WP + L DY + FK
Sbjct: 168 --SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQV 225
Query: 250 AQELRHIFSAASEDLIFLLESLLALYPPNR 279
L + S + LL L LYPP++
Sbjct: 226 PMPLEEVLPDVSPQALDLLGQFL-LYPPHQ 254
>AF015256-1|AAC51758.1| 365|Homo sapiens p38 mitogen-activated
protein kinase protein.
Length = 365
Score = 164 bits (399), Expect = 3e-40
Identities = 112/312 (35%), Positives = 162/312 (51%), Gaps = 19/312 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLIGL 73
+G G + +V A D ++ + VA+KK SR + + A RE+ LL+ +QH N+IGL
Sbjct: 31 VGSGAYGSVCSAIDKRSGEKVAIKK---PSRPFQSEIFAKRAYRELLLLKHMQHENVIGL 87
Query: 74 LDVFGQKSNVS------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
LDVF S++ LV FM TDL+ I+ + + ++ + LKGL+Y+H
Sbjct: 88 LDVFTPASSLRNFYDFYLVMPFMQTDLQKIMG---MEFSEEKIQYLVYQMLKGLKYIHSA 144
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
++HRDLKP L +N + LK+ DFGLA+ + T VVTRWYRAPE++ Y
Sbjct: 145 GVVHRDLKPGNLAVNEDCELKVLDFGLARHADAEM---TGYVVTRWYRAPEVILSWMHYN 201
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGM--KTLTDYVQ- 244
VD+W+VGCI+AE+L G+ LDQL++I +V G P E + K Y+Q
Sbjct: 202 QTVDIWSVGCIMAEMLTGKTLFRGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQS 261
Query: 245 FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLP 304
P ++ +F AS LLE +L L R QAL +F P +
Sbjct: 262 LPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQ 321
Query: 305 MPSNISKLEVEK 316
P + S LE EK
Sbjct: 322 QPFDDS-LEHEK 332
>AY994058-1|AAY44299.1| 254|Homo sapiens extracellular regulated
kinase 8 delta protein.
Length = 254
Score = 164 bits (398), Expect = 5e-40
Identities = 93/226 (41%), Positives = 133/226 (58%), Gaps = 12/226 (5%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQEL-QHINLIG 72
LG+G + V+KA D +T ++VA+KKI R + D RT REI LLQE H N+I
Sbjct: 19 LGQGAYGIVWKAVDRRTGEVVAIKKIFDAFR-DKTDA-QRT-FREITLLQEFGDHPNIIS 75
Query: 73 LLDVFGQKSN--VSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQNWIL 130
LLDV +++ + LVF+FMDTDL +I+ + L V++ L+ +LH ++
Sbjct: 76 LLDVIRAENDRDIYLVFEFMDTDLNAVIRKGGL-LQDVRVRSIFYQLLRATRFLHSGHVV 134
Query: 131 HRDLKPNTLLINREGILKIGDFGLAKAFGS-----PTRINTHQVVTRWYRAPELLFGARQ 185
HRD KP+ +L++ +K+ DFGLA++ G + T V TRWYRAPE+L + +
Sbjct: 135 HRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEVLLSSHR 194
Query: 186 YGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEE 231
Y GVDMW++GCIL E+L P PG S L QL I + P+EE
Sbjct: 195 YTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEE 240
>AF004709-1|AAC51374.1| 365|Homo sapiens stress-activated protein
kinase 4 protein.
Length = 365
Score = 164 bits (398), Expect = 5e-40
Identities = 112/312 (35%), Positives = 162/312 (51%), Gaps = 19/312 (6%)
Query: 14 LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLIGL 73
+G G + + A D ++ + VA+KK+ SR + + A RE+ LL+ +QH N+IGL
Sbjct: 31 VGSGAYGSWCSAIDKRSGEKVAIKKL---SRPFQSEIFAKRAYRELLLLKHMQHENVIGL 87
Query: 74 LDVFGQKSNVS------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQN 127
LDVF S++ LV FM TDL+ I+ + + ++ + LKGL+Y+H
Sbjct: 88 LDVFTPASSLRNFYDFYLVMPFMQTDLQKIMG---MEFSEEKIQYLVYQMLKGLKYIHSA 144
Query: 128 WILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGARQYG 187
++HRDLKP L +N + LKI DFGLA+ + T VVTRWYRAPE++ Y
Sbjct: 145 GVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM---TGYVVTRWYRAPEVILSWMHYN 201
Query: 188 TGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGM--KTLTDYVQ- 244
VD+W+VGCI+AE+L G+ LDQL++I +V G P E + K Y+Q
Sbjct: 202 QTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQS 261
Query: 245 FKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLP 304
P ++ +F AS LLE +L L R QAL +F P +
Sbjct: 262 LPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQ 321
Query: 305 MPSNISKLEVEK 316
P + S LE EK
Sbjct: 322 QPFDDS-LEHEK 332
>L40027-1|AAA62432.1| 483|Homo sapiens glycogen synthase kinase 3
protein.
Length = 483
Score = 163 bits (397), Expect = 6e-40
Identities = 109/313 (34%), Positives = 168/313 (53%), Gaps = 33/313 (10%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y I +G G F VY+A+ A+T ++VA+KK+ QD R RE++++++L H
Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKV-------LQD--KRFKNRELQIMRKLDH 169
Query: 68 INLIGLLDVF---GQKSN---VSLVFDFMDTDLEIIIKDNT---IVLTPANVKAYMIMTL 118
N++ L F G+K + ++LV +++ + + + T + + VK YM
Sbjct: 170 CNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLF 229
Query: 119 KGLEYLHQNWILHRDLKPNTLLINRE-GILKIGDFGLAKAF--GSPTRINTHQVVTRWYR 175
+ L Y+H + HRD+KP LL++ + +LK+ DFG AK G P N + +R+YR
Sbjct: 230 RSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEP---NVSYICSRYYR 286
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
APEL+FGA Y + +D+W+ GC+LAELLL P PG+S +DQL I +V GTPT E
Sbjct: 287 APELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIRE 346
Query: 236 MKTLTDYVQFKLFP---AQELRHIF-SAASEDLIFLLESLLALYPPNRCDCTQALQMAYF 291
M +Y +FK FP A +F S + I L SLL P +R +A ++F
Sbjct: 347 MN--PNYTEFK-FPQIKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLEACAHSFF 403
Query: 292 SSKPAPSVGPKLP 304
+G +LP
Sbjct: 404 DE--LRCLGTQLP 414
>D63424-1|BAA23608.1| 483|Homo sapiens glycogen synthase kinase
3alpha protein.
Length = 483
Score = 163 bits (397), Expect = 6e-40
Identities = 109/313 (34%), Positives = 168/313 (53%), Gaps = 33/313 (10%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y I +G G F VY+A+ A+T ++VA+KK+ QD R RE++++++L H
Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKV-------LQD--KRFKNRELQIMRKLDH 169
Query: 68 INLIGLLDVF---GQKSN---VSLVFDFMDTDLEIIIKDNT---IVLTPANVKAYMIMTL 118
N++ L F G+K + ++LV +++ + + + T + + VK YM
Sbjct: 170 CNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLF 229
Query: 119 KGLEYLHQNWILHRDLKPNTLLINRE-GILKIGDFGLAKAF--GSPTRINTHQVVTRWYR 175
+ L Y+H + HRD+KP LL++ + +LK+ DFG AK G P N + +R+YR
Sbjct: 230 RSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEP---NVSYICSRYYR 286
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
APEL+FGA Y + +D+W+ GC+LAELLL P PG+S +DQL I +V GTPT E
Sbjct: 287 APELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIRE 346
Query: 236 MKTLTDYVQFKLFP---AQELRHIF-SAASEDLIFLLESLLALYPPNRCDCTQALQMAYF 291
M +Y +FK FP A +F S + I L SLL P +R +A ++F
Sbjct: 347 MN--PNYTEFK-FPQIKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLEACAHSFF 403
Query: 292 SSKPAPSVGPKLP 304
+G +LP
Sbjct: 404 DE--LRCLGTQLP 414
>BC051865-1|AAH51865.1| 483|Homo sapiens glycogen synthase kinase 3
alpha protein.
Length = 483
Score = 163 bits (397), Expect = 6e-40
Identities = 109/313 (34%), Positives = 168/313 (53%), Gaps = 33/313 (10%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y I +G G F VY+A+ A+T ++VA+KK+ QD R RE++++++L H
Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKV-------LQD--KRFKNRELQIMRKLDH 169
Query: 68 INLIGLLDVF---GQKSN---VSLVFDFMDTDLEIIIKDNT---IVLTPANVKAYMIMTL 118
N++ L F G+K + ++LV +++ + + + T + + VK YM
Sbjct: 170 CNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLF 229
Query: 119 KGLEYLHQNWILHRDLKPNTLLINRE-GILKIGDFGLAKAF--GSPTRINTHQVVTRWYR 175
+ L Y+H + HRD+KP LL++ + +LK+ DFG AK G P N + +R+YR
Sbjct: 230 RSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEP---NVSYICSRYYR 286
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
APEL+FGA Y + +D+W+ GC+LAELLL P PG+S +DQL I +V GTPT E
Sbjct: 287 APELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIRE 346
Query: 236 MKTLTDYVQFKLFP---AQELRHIF-SAASEDLIFLLESLLALYPPNRCDCTQALQMAYF 291
M +Y +FK FP A +F S + I L SLL P +R +A ++F
Sbjct: 347 MN--PNYTEFK-FPQIKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLEACAHSFF 403
Query: 292 SSKPAPSVGPKLP 304
+G +LP
Sbjct: 404 DE--LRCLGTQLP 414
>BC027984-1|AAH27984.1| 483|Homo sapiens glycogen synthase kinase 3
alpha protein.
Length = 483
Score = 163 bits (397), Expect = 6e-40
Identities = 109/313 (34%), Positives = 168/313 (53%), Gaps = 33/313 (10%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y I +G G F VY+A+ A+T ++VA+KK+ QD R RE++++++L H
Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKV-------LQD--KRFKNRELQIMRKLDH 169
Query: 68 INLIGLLDVF---GQKSN---VSLVFDFMDTDLEIIIKDNT---IVLTPANVKAYMIMTL 118
N++ L F G+K + ++LV +++ + + + T + + VK YM
Sbjct: 170 CNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLF 229
Query: 119 KGLEYLHQNWILHRDLKPNTLLINRE-GILKIGDFGLAKAF--GSPTRINTHQVVTRWYR 175
+ L Y+H + HRD+KP LL++ + +LK+ DFG AK G P N + +R+YR
Sbjct: 230 RSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEP---NVSYICSRYYR 286
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
APEL+FGA Y + +D+W+ GC+LAELLL P PG+S +DQL I +V GTPT E
Sbjct: 287 APELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIRE 346
Query: 236 MKTLTDYVQFKLFP---AQELRHIF-SAASEDLIFLLESLLALYPPNRCDCTQALQMAYF 291
M +Y +FK FP A +F S + I L SLL P +R +A ++F
Sbjct: 347 MN--PNYTEFK-FPQIKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLEACAHSFF 403
Query: 292 SSKPAPSVGPKLP 304
+G +LP
Sbjct: 404 DE--LRCLGTQLP 414
>BC001274-1|AAH01274.1| 324|Homo sapiens CDC2L5 protein protein.
Length = 324
Score = 163 bits (397), Expect = 6e-40
Identities = 81/226 (35%), Positives = 136/226 (60%), Gaps = 14/226 (6%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
+++ I +GEG + VYKA+D T ++VA+KK+++ + E G TA+REIK+L++L
Sbjct: 90 KFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKE---GFPITAIREIKILRQLT 146
Query: 67 HINLIGLLDVFGQKSNVS----------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIM 116
H ++I + ++ K + LVF++MD DL +++ + ++K++M
Sbjct: 147 HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQ 206
Query: 117 TLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGS-PTRINTHQVVTRWYR 175
++GL+Y H+ LHRD+K + +L+N G +K+ DFGLA+ + S +R T++V+T WYR
Sbjct: 207 LMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYR 266
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRI 221
PELL G +Y +D+W+ GCIL EL + P +L QL I
Sbjct: 267 PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELI 312
>AC006486-1|AAD11986.1| 483|Homo sapiens KG3A_HUMAN protein.
Length = 483
Score = 163 bits (397), Expect = 6e-40
Identities = 109/313 (34%), Positives = 168/313 (53%), Gaps = 33/313 (10%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y I +G G F VY+A+ A+T ++VA+KK+ QD R RE++++++L H
Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKV-------LQD--KRFKNRELQIMRKLDH 169
Query: 68 INLIGLLDVF---GQKSN---VSLVFDFMDTDLEIIIKDNT---IVLTPANVKAYMIMTL 118
N++ L F G+K + ++LV +++ + + + T + + VK YM
Sbjct: 170 CNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLF 229
Query: 119 KGLEYLHQNWILHRDLKPNTLLINRE-GILKIGDFGLAKAF--GSPTRINTHQVVTRWYR 175
+ L Y+H + HRD+KP LL++ + +LK+ DFG AK G P N + +R+YR
Sbjct: 230 RSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEP---NVSYICSRYYR 286
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
APEL+FGA Y + +D+W+ GC+LAELLL P PG+S +DQL I +V GTPT E
Sbjct: 287 APELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIRE 346
Query: 236 MKTLTDYVQFKLFP---AQELRHIF-SAASEDLIFLLESLLALYPPNRCDCTQALQMAYF 291
M +Y +FK FP A +F S + I L SLL P +R +A ++F
Sbjct: 347 MN--PNYTEFK-FPQIKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLEACAHSFF 403
Query: 292 SSKPAPSVGPKLP 304
+G +LP
Sbjct: 404 DE--LRCLGTQLP 414
>BC024247-1|AAH24247.1| 502|Homo sapiens CDC2L6 protein protein.
Length = 502
Score = 163 bits (395), Expect = 1e-39
Identities = 118/299 (39%), Positives = 155/299 (51%), Gaps = 44/299 (14%)
Query: 50 GINRTALREIKLLQELQHINLIGLLDVFGQKSN--VSLVFDFMDTDLEIIIK-------- 99
GI+ +A REI LL+EL+H N+I L VF S+ V L+FD+ + DL IIK
Sbjct: 58 GISMSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKAN 117
Query: 100 DNTIVLTPANVKAYMIMTLKGLEYLHQNWILHRDLKPNTLLINREGI----LKIGDFGLA 155
+ L + VK+ + L G+ YLH NW+LHRDLKP +L+ EG +KI D G A
Sbjct: 118 KKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFA 177
Query: 156 KAFGSPTRINTHQ---VVTRWYRAPELLFGARQYGTGVDMWAVGCILAELLLRVP-FLPG 211
+ F SP + VVT WYRAPELL GAR Y +D+WA+GCI AELL P F
Sbjct: 178 RLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCR 237
Query: 212 ESDL--------DQLSRIFQVFGTPTEENW------PGMKTL------TDYVQFKLFPAQ 251
+ D+ DQL RIF V G P +++W P TL T Y L
Sbjct: 238 QEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYM 297
Query: 252 ELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSV----GPKLPMP 306
E +H S+ + LL+ LL + P R QALQ YF P P++ G ++P P
Sbjct: 298 E-KHKVKPDSK-VFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYP 354
>U66243-1|AAB40118.1| 367|Homo sapiens p38gamma MAP Kinase protein.
Length = 367
Score = 162 bits (393), Expect = 2e-39
Identities = 108/295 (36%), Positives = 150/295 (50%), Gaps = 17/295 (5%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y + +G G + V A D +T VA+KK+ + E + A RE++LL+ ++H
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSEL---FAKRAYRELRLLKHMRH 83
Query: 68 INLIGLLDVFGQKSNVS------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
N+IGLLDVF + LV FM TDL ++K L ++ + LKGL
Sbjct: 84 ENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEK--LGEDRIQFLVYQMLKGL 141
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLF 181
Y+H I+HRDLKP L +N + LKI DFGLA+ S T VVTRWYRAPE++
Sbjct: 142 RYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEM---TGYVVTRWYRAPEVIL 198
Query: 182 GARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTD 241
+Y VD+W+VGCI+AE++ G LDQL I +V GTP E +++
Sbjct: 199 NWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSDEA 258
Query: 242 YVQFKLFPAQELR---HIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
K P E + I + AS + LLE +L L R +AL YF S
Sbjct: 259 KNNMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAGEALAHPYFES 313
>Y10487-1|CAA71511.1| 367|Homo sapiens stress-activated protein
kinase-3 protein.
Length = 367
Score = 161 bits (392), Expect = 2e-39
Identities = 108/295 (36%), Positives = 150/295 (50%), Gaps = 17/295 (5%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y + +G G + V A D +T VA+KK+ + E + A RE++LL+ ++H
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSEL---FAKRAYRELRLLKHMRH 83
Query: 68 INLIGLLDVFGQKSNVS------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
N+IGLLDVF + LV FM TDL ++K L ++ + LKGL
Sbjct: 84 ENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEK--LGEDRIQFLVYQMLKGL 141
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLF 181
Y+H I+HRDLKP L +N + LKI DFGLA+ S T VVTRWYRAPE++
Sbjct: 142 RYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEM---TGYVVTRWYRAPEVIL 198
Query: 182 GARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTD 241
+Y VD+W+VGCI+AE++ G LDQL I +V GTP E +++
Sbjct: 199 NWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSDEA 258
Query: 242 YVQFKLFPAQELR---HIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
K P E + I + AS + LLE +L L R +AL YF S
Sbjct: 259 KNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAGEALAHPYFES 313
>BC015741-1|AAH15741.1| 367|Homo sapiens mitogen-activated protein
kinase 12 protein.
Length = 367
Score = 161 bits (392), Expect = 2e-39
Identities = 108/295 (36%), Positives = 150/295 (50%), Gaps = 17/295 (5%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y + +G G + V A D +T VA+KK+ + E + A RE++LL+ ++H
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSEL---FAKRAYRELRLLKHMRH 83
Query: 68 INLIGLLDVFGQKSNVS------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
N+IGLLDVF + LV FM TDL ++K L ++ + LKGL
Sbjct: 84 ENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEK--LGEDRIQFLVYQMLKGL 141
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLF 181
Y+H I+HRDLKP L +N + LKI DFGLA+ S T VVTRWYRAPE++
Sbjct: 142 RYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEM---TGYVVTRWYRAPEVIL 198
Query: 182 GARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTD 241
+Y VD+W+VGCI+AE++ G LDQL I +V GTP E +++
Sbjct: 199 NWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSDEA 258
Query: 242 YVQFKLFPAQELR---HIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
K P E + I + AS + LLE +L L R +AL YF S
Sbjct: 259 KNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAGEALAHPYFES 313
>AL022328-12|CAB51538.1| 367|Homo sapiens mitogen-activated protein
kinase 12 protein.
Length = 367
Score = 161 bits (392), Expect = 2e-39
Identities = 108/295 (36%), Positives = 150/295 (50%), Gaps = 17/295 (5%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y + +G G + V A D +T VA+KK+ + E + A RE++LL+ ++H
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSEL---FAKRAYRELRLLKHMRH 83
Query: 68 INLIGLLDVFGQKSNVS------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
N+IGLLDVF + LV FM TDL ++K L ++ + LKGL
Sbjct: 84 ENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEK--LGEDRIQFLVYQMLKGL 141
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLF 181
Y+H I+HRDLKP L +N + LKI DFGLA+ S T VVTRWYRAPE++
Sbjct: 142 RYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEM---TGYVVTRWYRAPEVIL 198
Query: 182 GARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTD 241
+Y VD+W+VGCI+AE++ G LDQL I +V GTP E +++
Sbjct: 199 NWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSDEA 258
Query: 242 YVQFKLFPAQELR---HIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
K P E + I + AS + LLE +L L R +AL YF S
Sbjct: 259 KNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAGEALAHPYFES 313
>AL603914-2|CAI41172.1| 442|Homo sapiens cell division cycle 2-like
6 (CDK8-like) protein.
Length = 442
Score = 159 bits (385), Expect = 2e-38
Identities = 116/295 (39%), Positives = 152/295 (51%), Gaps = 44/295 (14%)
Query: 54 TALREIKLLQELQHINLIGLLDVFGQKSN--VSLVFDFMDTDLEIIIK--------DNTI 103
+A REI LL+EL+H N+I L VF S+ V L+FD+ + DL IIK +
Sbjct: 2 SACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPM 61
Query: 104 VLTPANVKAYMIMTLKGLEYLHQNWILHRDLKPNTLLINREGI----LKIGDFGLAKAFG 159
L + VK+ + L G+ YLH NW+LHRDLKP +L+ EG +KI D G A+ F
Sbjct: 62 QLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFN 121
Query: 160 SPTRINTHQ---VVTRWYRAPELLFGARQYGTGVDMWAVGCILAELLLRVP-FLPGESDL 215
SP + VVT WYRAPELL GAR Y +D+WA+GCI AELL P F + D+
Sbjct: 122 SPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDI 181
Query: 216 --------DQLSRIFQVFGTPTEENW------PGMKTL------TDYVQFKLFPAQELRH 255
DQL RIF V G P +++W P TL T Y L E +H
Sbjct: 182 KTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYME-KH 240
Query: 256 IFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSV----GPKLPMP 306
S+ + LL+ LL + P R QALQ YF P P++ G ++P P
Sbjct: 241 KVKPDSK-VFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYP 294
>AL512430-1|CAI40282.1| 442|Homo sapiens cell division cycle 2-like
6 (CDK8-like) protein.
Length = 442
Score = 159 bits (385), Expect = 2e-38
Identities = 116/295 (39%), Positives = 152/295 (51%), Gaps = 44/295 (14%)
Query: 54 TALREIKLLQELQHINLIGLLDVFGQKSN--VSLVFDFMDTDLEIIIK--------DNTI 103
+A REI LL+EL+H N+I L VF S+ V L+FD+ + DL IIK +
Sbjct: 2 SACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPM 61
Query: 104 VLTPANVKAYMIMTLKGLEYLHQNWILHRDLKPNTLLINREGI----LKIGDFGLAKAFG 159
L + VK+ + L G+ YLH NW+LHRDLKP +L+ EG +KI D G A+ F
Sbjct: 62 QLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFN 121
Query: 160 SPTRINTHQ---VVTRWYRAPELLFGARQYGTGVDMWAVGCILAELLLRVP-FLPGESDL 215
SP + VVT WYRAPELL GAR Y +D+WA+GCI AELL P F + D+
Sbjct: 122 SPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDI 181
Query: 216 --------DQLSRIFQVFGTPTEENW------PGMKTL------TDYVQFKLFPAQELRH 255
DQL RIF V G P +++W P TL T Y L E +H
Sbjct: 182 KTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYME-KH 240
Query: 256 IFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSV----GPKLPMP 306
S+ + LL+ LL + P R QALQ YF P P++ G ++P P
Sbjct: 241 KVKPDSK-VFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYP 294
>AC006036-1|AAF19245.1| 165|Homo sapiens unknown protein.
Length = 165
Score = 157 bits (380), Expect = 7e-38
Identities = 75/163 (46%), Positives = 107/163 (65%), Gaps = 1/163 (0%)
Query: 61 LLQELQHINLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKG 120
LL+ L+H N++ L D+ K ++LVF+++ TDL + + L P NVK ++ L+G
Sbjct: 2 LLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRG 61
Query: 121 LEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELL 180
L Y+HQ +ILHRDLKP LLI+ G LK+ DFGLA+A P+ +++VVT WYR P++L
Sbjct: 62 LSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVL 121
Query: 181 FGARQYGTGVDMWAVGCILAELLLRVPFLPGESDL-DQLSRIF 222
G+ +Y T +DMW VGCI E++ V PG D+ DQL RIF
Sbjct: 122 LGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIF 164
>X79483-1|CAA55984.1| 367|Homo sapiens extracellular signal
regulated kinase protein.
Length = 367
Score = 156 bits (379), Expect = 9e-38
Identities = 107/295 (36%), Positives = 147/295 (49%), Gaps = 17/295 (5%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y + +G G + V A D +T VA+KK+ + E + A RE++LL+ ++H
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSEL---FAKLAYRELRLLKHMRH 83
Query: 68 INLIGLLDVFGQKSNVS------LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
N+IGLLDVF + LV FM TDL ++K + Y +M KGL
Sbjct: 84 ENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEKLGEDRIQFLVYQMM--KGL 141
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLF 181
Y+H I+HRDLKP L +N + LKI DFGLA+ S T VVTRWYRAPE++
Sbjct: 142 RYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEM---TGYVVTRWYRAPEVIL 198
Query: 182 GARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTD 241
Y VD+W+VGCI+AE++ G LDQL I +V GTP E +++
Sbjct: 199 NWIAYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSDEA 258
Query: 242 YVQFKLFPAQELR---HIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSS 293
K P E + I + AS + LLE +L L R + L YF S
Sbjct: 259 KNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDADIRLTAGEFLSHPYFES 313
>CR536510-1|CAG38748.1| 420|Homo sapiens GSK3B protein.
Length = 420
Score = 155 bits (376), Expect = 2e-37
Identities = 109/313 (34%), Positives = 163/313 (52%), Gaps = 33/313 (10%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y +G G F VY+AK + ++VA+KK+ QD R RE++++++L H
Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKV-------LQD--KRFKNRELQIMRKLDH 106
Query: 68 INLIGLLDVF---GQKSN---VSLVFDFMDTDLEIIIKDNTIV---LTPANVKAYMIMTL 118
N++ L F G+K + ++LV D++ + + + + L VK YM
Sbjct: 107 CNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLF 166
Query: 119 KGLEYLHQNWILHRDLKPNTLLINRE-GILKIGDFGLAKAF--GSPTRINTHQVVTRWYR 175
+ L Y+H I HRD+KP LL++ + +LK+ DFG AK G P N + +R+YR
Sbjct: 167 RSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEP---NVSYICSRYYR 223
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
APEL+FGA Y + +D+W+ GC+LAELLL P PG+S +DQL I +V GTPT E
Sbjct: 224 APELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIRE 283
Query: 236 MKTLTDYVQFKLFP---AQELRHIFSAAS-EDLIFLLESLLALYPPNRCDCTQALQMAYF 291
M +Y +FK FP A +F + + I L LL P R +A ++F
Sbjct: 284 MN--PNYTEFK-FPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFF 340
Query: 292 SSKPAPSVGPKLP 304
P+V KLP
Sbjct: 341 DELRDPNV--KLP 351
>BC012760-1|AAH12760.1| 420|Homo sapiens GSK3B protein protein.
Length = 420
Score = 155 bits (376), Expect = 2e-37
Identities = 109/313 (34%), Positives = 163/313 (52%), Gaps = 33/313 (10%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y +G G F VY+AK + ++VA+KK+ QD R RE++++++L H
Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKV-------LQD--KRFKNRELQIMRKLDH 106
Query: 68 INLIGLLDVF---GQKSN---VSLVFDFMDTDLEIIIKDNTIV---LTPANVKAYMIMTL 118
N++ L F G+K + ++LV D++ + + + + L VK YM
Sbjct: 107 CNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLF 166
Query: 119 KGLEYLHQNWILHRDLKPNTLLINRE-GILKIGDFGLAKAF--GSPTRINTHQVVTRWYR 175
+ L Y+H I HRD+KP LL++ + +LK+ DFG AK G P N + +R+YR
Sbjct: 167 RSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEP---NVSYICSRYYR 223
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
APEL+FGA Y + +D+W+ GC+LAELLL P PG+S +DQL I +V GTPT E
Sbjct: 224 APELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIRE 283
Query: 236 MKTLTDYVQFKLFP---AQELRHIFSAAS-EDLIFLLESLLALYPPNRCDCTQALQMAYF 291
M +Y +FK FP A +F + + I L LL P R +A ++F
Sbjct: 284 MN--PNYTEFK-FPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFF 340
Query: 292 SSKPAPSVGPKLP 304
P+V KLP
Sbjct: 341 DELRDPNV--KLP 351
>BX537897-1|CAD97888.1| 323|Homo sapiens hypothetical protein
protein.
Length = 323
Score = 155 bits (375), Expect = 3e-37
Identities = 99/284 (34%), Positives = 150/284 (52%), Gaps = 17/284 (5%)
Query: 34 VAVKKIKIGSRLEAQDGINRTALREIKLLQELQHINLIGLLDVFGQKS-----NVSLVFD 88
VA+KKI S E Q RT LREI++L +H N+IG+ D+ + +V +V D
Sbjct: 12 VAIKKI---SPFEHQTYCQRT-LREIQILLRFRHENVIGIRDILRASTLEAMRDVYIVQD 67
Query: 89 FMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQNWILHRDLKPNTLLINREGILK 148
M+TDL ++K L+ ++ ++ L+GL+Y+H +LHRDLKP+ LLIN LK
Sbjct: 68 LMETDLYKLLKSQQ--LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLK 125
Query: 149 IGDFGLAKAFGSP---TRINTHQVVTRWYRAPELLFGARQYGTGVDMWAVGCILAELLLR 205
I DFGLA+ T T V TRWYRAPE++ ++ Y +D+W+VGCILAE+L
Sbjct: 126 ICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN 185
Query: 206 VPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDYVQFKLFPAQ---ELRHIFSAASE 262
P PG+ LDQL+ I + G+P++E+ + + + P++ +F +
Sbjct: 186 RPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDS 245
Query: 263 DLIFLLESLLALYPPNRCDCTQALQMAYFSSKPAPSVGPKLPMP 306
+ LL+ +L P R +AL Y P+ P P
Sbjct: 246 KALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEP 289
>L33801-1|AAA66475.1| 420|Homo sapiens protein kinase protein.
Length = 420
Score = 154 bits (373), Expect = 5e-37
Identities = 106/308 (34%), Positives = 160/308 (51%), Gaps = 31/308 (10%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y +G G F VY+AK + ++VA+KK+ QD R RE++++++L H
Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKV-------LQD--KRFKNRELQIMRKLDH 106
Query: 68 INLIGLLDVF---GQKSN---VSLVFDFMDTDLEIIIKDNTIV---LTPANVKAYMIMTL 118
N++ L F G+K + ++LV D++ + + + + L VK YM
Sbjct: 107 CNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLF 166
Query: 119 KGLEYLHQNWILHRDLKPNTLLINRE-GILKIGDFGLAKAF--GSPTRINTHQVVTRWYR 175
+ L Y+H I HRD+KP LL++ + +LK+ DFG AK G P N + +R+YR
Sbjct: 167 RSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEP---NVSYICSRYYR 223
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
APEL+FGA Y + +D+W+ GC+LAELLL P PG+S +DQL I +V GTPT E
Sbjct: 224 APELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIRE 283
Query: 236 MKTLTDYVQFKLFP---AQELRHIFSAAS-EDLIFLLESLLALYPPNRCDCTQALQMAYF 291
M +Y +FK FP A +F + + I L LL P R +A ++F
Sbjct: 284 MN--PNYTEFK-FPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFF 340
Query: 292 SSKPAPSV 299
P+V
Sbjct: 341 DELRDPNV 348
>U19775-1|AAC50329.1| 297|Homo sapiens Mxi2 protein.
Length = 297
Score = 153 bits (372), Expect = 6e-37
Identities = 94/231 (40%), Positives = 131/231 (56%), Gaps = 14/231 (6%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY+ + +G G + +V A D KT VAVKK+ ++ RT RE++LL+ ++
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLS--RPFQSIIHAKRT-YRELRLLKHMK 79
Query: 67 HINLIGLLDVFG------QKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKG 120
H N+IGLLDVF + ++V LV M DL I+K LT +V+ + L+G
Sbjct: 80 HENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQK--LTDDHVQFLIYQILRG 137
Query: 121 LEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELL 180
L+Y+H I+HRDLKP+ L +N + LKI DFGLA+ T V TRWYRAPE++
Sbjct: 138 LKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEM---TGYVATRWYRAPEIM 194
Query: 181 FGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEE 231
Y VD+W+VGCI+AELL PG +DQL I ++ GTP E
Sbjct: 195 LNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAE 245
>AB074150-1|BAB85654.1| 307|Homo sapiens Alternative spliced
variant of p38alpha EXIP protein.
Length = 307
Score = 153 bits (372), Expect = 6e-37
Identities = 94/231 (40%), Positives = 131/231 (56%), Gaps = 14/231 (6%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY+ + +G G + +V A D KT VAVKK+ ++ RT RE++LL+ ++
Sbjct: 23 RYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLS--RPFQSIIHAKRT-YRELRLLKHMK 79
Query: 67 HINLIGLLDVFG------QKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKG 120
H N+IGLLDVF + ++V LV M DL I+K LT +V+ + L+G
Sbjct: 80 HENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQK--LTDDHVQFLIYQILRG 137
Query: 121 LEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELL 180
L+Y+H I+HRDLKP+ L +N + LKI DFGLA+ T V TRWYRAPE++
Sbjct: 138 LKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEM---TGYVATRWYRAPEIM 194
Query: 181 FGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEE 231
Y VD+W+VGCI+AELL PG +DQL I ++ GTP E
Sbjct: 195 LNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAE 245
>AB022694-1|BAA81688.1| 419|Homo sapiens MOK protein kinase
protein.
Length = 419
Score = 153 bits (372), Expect = 6e-37
Identities = 95/291 (32%), Positives = 155/291 (53%), Gaps = 10/291 (3%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ- 66
Y+ I +GEG F+ V K + + A K++K R E+ + +N LREI+ L+ L
Sbjct: 4 YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMK--QRFESIEQVNN--LREIQALRRLNP 59
Query: 67 HINLIGLLDV-FGQKS-NVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYL 124
H N++ L +V F +KS +++L+ + MD ++ +I+ L+ + YM K L+++
Sbjct: 60 HPNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHI 119
Query: 125 HQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRWYRAPELLFGAR 184
H+N I HRD+KP +LI ++ +LK+GDFG ++ S T + TRWYRAPE L
Sbjct: 120 HRNGIFHRDVKPENILIKQD-VLKLGDFGSCRSVYSKQPY-TEYISTRWYRAPECLLTDG 177
Query: 185 QYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMK-TLTDYV 243
Y +D+W+ GC+ E+ P PG ++LDQ+S+I V GTP ++ K +
Sbjct: 178 FYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMNF 237
Query: 244 QFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFSSK 294
F + + + S + LL +++A P R QALQ YF +
Sbjct: 238 DFPFKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQEQ 288
>AY033608-1|AAK52330.1| 335|Homo sapiens extracellular
signal-related kinase 1c protein.
Length = 335
Score = 153 bits (370), Expect = 1e-36
Identities = 90/223 (40%), Positives = 129/223 (57%), Gaps = 14/223 (6%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY ++ ++GEG + V A D VA+KKI S E Q RT LREI++L +
Sbjct: 41 RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI---SPFEHQTYCQRT-LREIQILLRFR 96
Query: 67 HINLIGLLDVFGQKS-----NVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGL 121
H N+IG+ D+ + +V +V D M+TDL ++K L+ ++ ++ L+GL
Sbjct: 97 HENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQ--LSNDHICYFLYQILRGL 154
Query: 122 EYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSP---TRINTHQVVTRWYRAPE 178
+Y+H +LHRDLKP+ LL N LKI DFGLA+ T T V TRWYRAPE
Sbjct: 155 KYIHSANVLHRDLKPSNLLSNTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPE 214
Query: 179 LLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRI 221
++ ++ Y +D+W+VGCILAE+L P PG+ LDQL+ I
Sbjct: 215 IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI 257
>X59727-1|CAA42411.1| 557|Homo sapiens 63kDa protein kinase
protein.
Length = 557
Score = 151 bits (367), Expect = 3e-36
Identities = 103/317 (32%), Positives = 154/317 (48%), Gaps = 25/317 (7%)
Query: 11 IDF--LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHI 68
+DF LG G V A D++ + VAVKKI + + ALREIK+++ L H
Sbjct: 21 VDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMKH-----ALREIKIIRRLDHD 75
Query: 69 NLIGLLDVFGQK-----------SNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMT 117
N++ + +V G K S +V ++M+TDL +++ T L + K +M
Sbjct: 76 NIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGT--LAEEHAKLFMYQL 133
Query: 118 LKGLEYLHQNWILHRDLKPNTLLINREG-ILKIGDFGLAKAFG---SPTRINTHQVVTRW 173
L+GL+Y+H +LHRDLKP + I+ E +LKIGDFGLA+ S + +VT+W
Sbjct: 134 LRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYSHKGYLSEGLVTKW 193
Query: 174 YRAPELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENW 233
YR+P LL Y +DMWA GCILAE+L G +L+Q+ I + EE+
Sbjct: 194 YRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQLILETIPVIREEDK 253
Query: 234 PG-MKTLTDYVQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS 292
++ + +V + LR + + + I LE +L P +R LQ Y S
Sbjct: 254 DELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDRLTAEMGLQHPYMS 313
Query: 293 SKPAPSVGPKLPMPSNI 309
P P P I
Sbjct: 314 PYSCPEDEPTSQHPFRI 330
>BC117216-1|AAI17217.1| 587|Homo sapiens mitogen-activated protein
kinase 4 protein.
Length = 587
Score = 151 bits (367), Expect = 3e-36
Identities = 103/317 (32%), Positives = 154/317 (48%), Gaps = 25/317 (7%)
Query: 11 IDF--LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHI 68
+DF LG G V A D++ + VAVKKI + + ALREIK+++ L H
Sbjct: 21 VDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMKH-----ALREIKIIRRLDHD 75
Query: 69 NLIGLLDVFGQK-----------SNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMT 117
N++ + +V G K S +V ++M+TDL +++ T L + K +M
Sbjct: 76 NIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGT--LAEEHAKLFMYQL 133
Query: 118 LKGLEYLHQNWILHRDLKPNTLLINREG-ILKIGDFGLAKAFG---SPTRINTHQVVTRW 173
L+GL+Y+H +LHRDLKP + I+ E +LKIGDFGLA+ S + +VT+W
Sbjct: 134 LRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYSHKGYLSEGLVTKW 193
Query: 174 YRAPELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENW 233
YR+P LL Y +DMWA GCILAE+L G +L+Q+ I + EE+
Sbjct: 194 YRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQLILETIPVIREEDK 253
Query: 234 PG-MKTLTDYVQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS 292
++ + +V + LR + + + I LE +L P +R LQ Y S
Sbjct: 254 DELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDRLTAEMGLQHPYMS 313
Query: 293 SKPAPSVGPKLPMPSNI 309
P P P I
Sbjct: 314 PYSCPEDEPTSQHPFRI 330
>BC050299-1|AAH50299.1| 587|Homo sapiens mitogen-activated protein
kinase 4 protein.
Length = 587
Score = 151 bits (365), Expect = 5e-36
Identities = 102/317 (32%), Positives = 154/317 (48%), Gaps = 25/317 (7%)
Query: 11 IDF--LGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQHI 68
+DF LG G V A D++ + VAVKKI + + ALREIK+++ L H
Sbjct: 21 VDFQPLGFGVNGLVLSAMDSRACRKVAVKKIALSDARSMKH-----ALREIKIIRRLDHD 75
Query: 69 NLIGLLDVFGQK-----------SNVSLVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMT 117
N++ + +V G K S +V ++M+TDL +++ T L + K +M
Sbjct: 76 NIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGT--LAEEHAKLFMYQL 133
Query: 118 LKGLEYLHQNWILHRDLKPNTLLINREG-ILKIGDFGLAKAFG---SPTRINTHQVVTRW 173
L+GL+Y+H +LHRDLKP + I+ E +LKIGDFGLA+ S + +VT+W
Sbjct: 134 LRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYSHKGYLSEGLVTKW 193
Query: 174 YRAPELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENW 233
YR+P LL Y +DMWA GCIL+E+L G +L+Q+ I + EE+
Sbjct: 194 YRSPRLLLSPNNYTKAIDMWAAGCILSEMLTGRMLFAGAHELEQMQLILETIPVIREEDK 253
Query: 234 PG-MKTLTDYVQFKLFPAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQALQMAYFS 292
++ + +V + LR + + + I LE +L P +R LQ Y S
Sbjct: 254 DELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDRLTAEMGLQHPYMS 313
Query: 293 SKPAPSVGPKLPMPSNI 309
P P P I
Sbjct: 314 PYSCPEDEPTSQHPFRI 330
>AC006023-1|AAD54514.1| 727|Homo sapiens WUGSC:H_DJ1147A01.1
protein.
Length = 727
Score = 151 bits (365), Expect = 5e-36
Identities = 80/243 (32%), Positives = 135/243 (55%), Gaps = 4/243 (1%)
Query: 85 LVFDFMDTDLEIIIKDNTIVLTPANVKAYMIMTLKGLEYLHQNWILHRDLKPNTLLINRE 144
LVF++MD DL +++ + ++K++M ++GL+Y H+ LHRD+K + +L+N
Sbjct: 4 LVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNR 63
Query: 145 GILKIGDFGLAKAFGSP-TRINTHQVVTRWYRAPELLFGARQYGTGVDMWAVGCILAELL 203
G +K+ DFGLA+ + S +R T++V+T WYR PELL G +Y +D+W+ GCIL EL
Sbjct: 64 GQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELF 123
Query: 204 LRVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDY--VQFKLFPAQELRHIFSAAS 261
+ P +L QL I ++ G+P WP + L + ++ K ++LR F
Sbjct: 124 TKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEFVFIP 183
Query: 262 EDLIFLLESLLALYPPNRCDCTQALQMAYFSS-KPAPSVGPKLPMPSNISKLEVEKPSLK 320
+ L + +LAL P RC QALQ + +P+ P LP+ + +L +K +
Sbjct: 184 AAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKRRRQ 243
Query: 321 RKL 323
+++
Sbjct: 244 KQM 246
>BC000251-1|AAH00251.1| 433|Homo sapiens glycogen synthase kinase 3
beta protein.
Length = 433
Score = 150 bits (364), Expect = 6e-36
Identities = 94/254 (37%), Positives = 141/254 (55%), Gaps = 27/254 (10%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
Y +G G F VY+AK + ++VA+KK+ QD R RE++++++L H
Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKV-------LQD--KRFKNRELQIMRKLDH 106
Query: 68 INLIGLLDVF---GQKSN---VSLVFDFMDTDLEIIIKDNTIV---LTPANVKAYMIMTL 118
N++ L F G+K + ++LV D++ + + + + L VK YM
Sbjct: 107 CNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLF 166
Query: 119 KGLEYLHQNWILHRDLKPNTLLINRE-GILKIGDFGLAKAF--GSPTRINTHQVVTRWYR 175
+ L Y+H I HRD+KP LL++ + +LK+ DFG AK G P N + +R+YR
Sbjct: 167 RSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEP---NVSYICSRYYR 223
Query: 176 APELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENWPG 235
APEL+FGA Y + +D+W+ GC+LAELLL P PG+S +DQL I +V GTPT E
Sbjct: 224 APELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIRE 283
Query: 236 MKTLTDYVQFKLFP 249
M +Y +FK FP
Sbjct: 284 MN--PNYTEFK-FP 294
>BC040529-1|AAH40529.1| 231|Homo sapiens PCTK3 protein protein.
Length = 231
Score = 149 bits (362), Expect = 1e-35
Identities = 73/161 (45%), Positives = 97/161 (60%), Gaps = 2/161 (1%)
Query: 114 MIMTLKGLEYLHQNWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTRW 173
M L+GL Y H ILHRDLKP LLIN G LK+ DFGLA+A PT+ +++VVT W
Sbjct: 1 MFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLW 60
Query: 174 YRAPELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTPTEENW 233
YR P++L G+ +Y T +DMW VGCI E+ P PG + ++L IF++ GTPTEE W
Sbjct: 61 YRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETW 120
Query: 234 PGMKTLTDY--VQFKLFPAQELRHIFSAASEDLIFLLESLL 272
PG+ +++ F + Q L + D I LL SLL
Sbjct: 121 PGVTAFSEFRTYSFPCYLPQPLINHAPRLDTDGIHLLSSLL 161
>BC035492-1|AAH35492.1| 721|Homo sapiens mitogen-activated protein
kinase 6 protein.
Length = 721
Score = 148 bits (359), Expect = 2e-35
Identities = 100/323 (30%), Positives = 157/323 (48%), Gaps = 27/323 (8%)
Query: 7 RYEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQ 66
RY + LG G V+ A D DK VA+KKI + + ALREIK+++ L
Sbjct: 19 RYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVKH-----ALREIKIIRRLD 73
Query: 67 HINLIGLLDVFG--------------QKSNVSLVFDFMDTDLEIIIKDNTIVLTPANVKA 112
H N++ + ++ G + ++V +V ++M+TDL +++ ++ + +
Sbjct: 74 HDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQGPLL--EEHARL 131
Query: 113 YMIMTLKGLEYLHQNWILHRDLKPNTLLINREG-ILKIGDFGLAKAFGSPTRINTHQ--- 168
+M L+GL+Y+H +LHRDLKP L IN E +LKIGDFGLA+ H
Sbjct: 132 FMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDPHYSHKGHLSEG 191
Query: 169 VVTRWYRAPELLFGARQYGTGVDMWAVGCILAELLLRVPFLPGESDLDQLSRIFQVFGTP 228
+VT+WYR+P LL Y +DMWA GCI AE+L G +L+Q+ I +
Sbjct: 192 LVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVV 251
Query: 229 TEENWPG-MKTLTDYVQFKLF-PAQELRHIFSAASEDLIFLLESLLALYPPNRCDCTQAL 286
EE+ + + Y++ + P + L + S + + LE +L P +R +AL
Sbjct: 252 HEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPGISREAVDFLEQILTFSPMDRLTAEEAL 311
Query: 287 QMAYFSSKPAPSVGPKLPMPSNI 309
Y S P P P +I
Sbjct: 312 SHPYMSIYSFPMDEPISSHPFHI 334
>AB012305-1|BAA32794.1| 264|Homo sapiens d-HSCDK2 protein.
Length = 264
Score = 148 bits (359), Expect = 2e-35
Identities = 71/166 (42%), Positives = 110/166 (66%), Gaps = 4/166 (2%)
Query: 8 YEKIDFLGEGQFATVYKAKDAKTDKIVAVKKIKIGSRLEAQDGINRTALREIKLLQELQH 67
++K+ +G+G + VYKA++ T ++VA+KKI++ + E G+ TA+REI LL+EL H
Sbjct: 4 FQKVAQIGQGTYGVVYKARNKSTGQMVALKKIRLDTETE---GVPSTAIREISLLKELNH 60
Query: 68 INLIGLLDVFGQKSNVSLVFDFMDTDLEIIIKDNTIVLTPAN-VKAYMIMTLKGLEYLHQ 126
N++ LLDV ++ + LVF+F+ DL+ + + + P +K+Y+ L+GL + H
Sbjct: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
Query: 127 NWILHRDLKPNTLLINREGILKIGDFGLAKAFGSPTRINTHQVVTR 172
+ +LHRDLKP LLIN EG +K+ DFGLA+AFG P R TH+V R
Sbjct: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVTRR 166
Score = 56.4 bits (130), Expect = 1e-07
Identities = 33/96 (34%), Positives = 46/96 (47%), Gaps = 3/96 (3%)
Query: 205 RVPFLPGESDLDQLSRIFQVFGTPTEENWPGMKTLTDY-VQFKLFPAQELRHIFSAASED 263
R PG+S++DQL RIF+ GTP E WPG+ ++ DY F + Q+ + ED
Sbjct: 165 RRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDED 224
Query: 264 LIFLLESLLALYPPNRCDCTQALQMAYFS--SKPAP 297
LL +L P R AL + +KP P
Sbjct: 225 GRSLLSQMLHYDPYKRFSTKAALAHPFLEDVTKPVP 260
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.322 0.139 0.410
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 49,639,624
Number of Sequences: 224733
Number of extensions: 2162398
Number of successful extensions: 13603
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 2298
Number of HSP's successfully gapped in prelim test: 477
Number of HSP's that attempted gapping in prelim test: 7016
Number of HSP's gapped (non-prelim): 3213
length of query: 338
length of database: 73,234,838
effective HSP length: 90
effective length of query: 248
effective length of database: 53,008,868
effective search space: 13146199264
effective search space used: 13146199264
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 66 (30.7 bits)
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