Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001536-TA|BGIBMGA001536-PA|IPR003010|Nitrilase/cyanide
hydratase and apolipoprotein N-acyltransferase
(385 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q6NP10 Cluster: LD13390p; n=7; Eukaryota|Rep: LD13390p ... 537 e-151
UniRef50_Q9UBR1 Cluster: Beta-ureidopropionase; n=42; root|Rep: ... 508 e-143
UniRef50_UPI0000DC0724 Cluster: ureidopropionase, beta; n=1; Rat... 412 e-114
UniRef50_A7SG03 Cluster: Predicted protein; n=1; Nematostella ve... 372 e-101
UniRef50_Q5L031 Cluster: Beta-alanine synthase; n=19; Bacteria|R... 212 2e-53
UniRef50_O61697 Cluster: Putative beta-ureidopropionase; n=1; Ma... 205 2e-51
UniRef50_Q1IQA8 Cluster: Nitrilase/cyanide hydratase and apolipo... 125 2e-27
UniRef50_Q97RA3 Cluster: Carbon-nitrogen hydrolase family protei... 118 3e-25
UniRef50_Q9ABL5 Cluster: Hydrolase, carbon-nitrogen family; n=13... 113 1e-23
UniRef50_A7I5W9 Cluster: Porphyromonas-type peptidyl-arginine de... 110 7e-23
UniRef50_Q8VYF5 Cluster: N-carbamoylputrescine amidase; n=60; ce... 110 7e-23
UniRef50_A6DKQ0 Cluster: Carbon-nitrogen hydrolase family protei... 109 2e-22
UniRef50_A4B9A7 Cluster: Probable hydratase; n=2; Bacteria|Rep: ... 108 2e-22
UniRef50_Q1GTC5 Cluster: Nitrilase/cyanide hydratase and apolipo... 107 6e-22
UniRef50_Q2S196 Cluster: Hydrolase, carbon-nitrogen family; n=1;... 105 3e-21
UniRef50_Q972L1 Cluster: 281aa long hypothetical beta-ureidoprop... 101 3e-20
UniRef50_A4J4S3 Cluster: Nitrilase/cyanide hydratase and apolipo... 99 1e-19
UniRef50_Q972X1 Cluster: 264aa long hypothetical beta-ureidoprop... 99 1e-19
UniRef50_Q606Z9 Cluster: Hydrolase, carbon-nitrogen family; n=38... 95 4e-18
UniRef50_Q6AHZ8 Cluster: Putative uncharacterized protein DKFZp7... 90 8e-17
UniRef50_Q89413 Cluster: A78R protein; n=6; Chlorovirus|Rep: A78... 90 1e-16
UniRef50_A6QC56 Cluster: Hydrolase; n=2; Bacteria|Rep: Hydrolase... 90 1e-16
UniRef50_A6DDT2 Cluster: HYDROLASE-Predicted amidohydrolase; n=1... 90 1e-16
UniRef50_Q7M8G2 Cluster: HYDROLASE-Predicted amidohydrolase; n=5... 85 2e-15
UniRef50_A5C5V4 Cluster: Putative uncharacterized protein; n=1; ... 85 4e-15
UniRef50_Q9UYV8 Cluster: Beta ureidopropionase; n=4; Thermococca... 84 7e-15
UniRef50_A7I2D9 Cluster: Hydrolase, carbon-nitrogen family; n=1;... 83 9e-15
UniRef50_A6CCK5 Cluster: Putative uncharacterized protein; n=1; ... 83 2e-14
UniRef50_Q2AH52 Cluster: Nitrilase/cyanide hydratase and apolipo... 80 8e-14
UniRef50_O59829 Cluster: Nitrilase; n=2; cellular organisms|Rep:... 80 1e-13
UniRef50_A6TPX2 Cluster: Nitrilase/cyanide hydratase and apolipo... 79 2e-13
UniRef50_Q0LQX0 Cluster: Nitrilase/cyanide hydratase and apolipo... 78 4e-13
UniRef50_A0QWL8 Cluster: Carbon-nitrogen hydrolase family protei... 78 4e-13
UniRef50_A7GE66 Cluster: Hydrolase, carbon-nitrogen family; n=13... 77 6e-13
UniRef50_Q0AX54 Cluster: N-carbamoyl-D-amino acid amidohydrolase... 73 2e-11
UniRef50_Q44185 Cluster: N-carbamoyl-D-amino acid hydrolase; n=1... 72 2e-11
UniRef50_Q183H2 Cluster: Putative carbon-nitrogen hydrolase; n=2... 72 3e-11
UniRef50_Q4P4D1 Cluster: Putative uncharacterized protein; n=1; ... 72 3e-11
UniRef50_Q6N746 Cluster: Nitrilase/cyanide hydratase and apolipo... 71 4e-11
UniRef50_A4J6K3 Cluster: Nitrilase/cyanide hydratase and apolipo... 71 4e-11
UniRef50_A4M5M1 Cluster: Nitrilase/cyanide hydratase and apolipo... 71 7e-11
UniRef50_A1HQ26 Cluster: Nitrilase/cyanide hydratase and apolipo... 70 1e-10
UniRef50_A0QPL8 Cluster: Hydrolase, carbon-nitrogen family prote... 70 1e-10
UniRef50_O30121 Cluster: Putative uncharacterized protein; n=1; ... 70 1e-10
UniRef50_A0JSY8 Cluster: Nitrilase/cyanide hydratase and apolipo... 69 2e-10
UniRef50_A6TL48 Cluster: Nitrilase/cyanide hydratase and apolipo... 69 2e-10
UniRef50_A0BLB1 Cluster: Chromosome undetermined scaffold_114, w... 69 2e-10
UniRef50_A6CCB9 Cluster: Predicted amidohydrolase; n=1; Planctom... 69 3e-10
UniRef50_Q6RWQ0 Cluster: Nitrilase; n=3; uncultured organism|Rep... 68 4e-10
UniRef50_A6BCC3 Cluster: Carbon-nitrogen hydrolase family protei... 68 5e-10
UniRef50_A1HPP3 Cluster: Nitrilase/cyanide hydratase and apolipo... 68 5e-10
UniRef50_Q8RUF8 Cluster: AT5g12040/F14F18_210; n=9; Magnoliophyt... 68 5e-10
UniRef50_A3H7D3 Cluster: Nitrilase/cyanide hydratase and apolipo... 67 8e-10
UniRef50_A7DPX6 Cluster: Nitrilase/cyanide hydratase and apolipo... 66 1e-09
UniRef50_A1S062 Cluster: Nitrilase/cyanide hydratase and apolipo... 66 1e-09
UniRef50_Q8W0T9 Cluster: Putative uncharacterized protein SB35P0... 64 4e-09
UniRef50_UPI000051A529 Cluster: PREDICTED: similar to Nitrilase ... 64 6e-09
UniRef50_Q54JM9 Cluster: Putative uncharacterized protein; n=1; ... 64 6e-09
UniRef50_Q2NHR0 Cluster: Predicted amidohydrolase; n=1; Methanos... 64 6e-09
UniRef50_Q1QTM0 Cluster: Nitrilase/cyanide hydratase and apolipo... 64 8e-09
UniRef50_Q74H63 Cluster: Hydrolase, carbon-nitrogen family; n=8;... 63 1e-08
UniRef50_Q84FR7 Cluster: D-N-carbamoylase; n=1; Arthrobacter cry... 62 2e-08
UniRef50_Q18UU7 Cluster: Nitrilase/cyanide hydratase and apolipo... 62 2e-08
UniRef50_Q75TH8 Cluster: Putative uncharacterized protein GSB07;... 62 2e-08
UniRef50_Q86X76 Cluster: Nitrilase homolog 1; n=29; Eumetazoa|Re... 62 3e-08
UniRef50_A2XD42 Cluster: Putative uncharacterized protein; n=2; ... 61 4e-08
UniRef50_Q6TGW8 Cluster: Nit protein 2; n=22; Fungi/Metazoa grou... 61 5e-08
UniRef50_Q9ZMC7 Cluster: Putative; n=6; Campylobacterales|Rep: P... 61 5e-08
UniRef50_Q8WUF0 Cluster: Nitrilase family member 2; n=28; cellul... 60 7e-08
UniRef50_A2BNC1 Cluster: Predicted amidohydrolase; n=1; Hyperthe... 60 7e-08
UniRef50_Q0RPB5 Cluster: Putative methylthioribose recycling pro... 60 1e-07
UniRef50_UPI0000E1FE2F Cluster: PREDICTED: similar to Nitrilase ... 60 1e-07
UniRef50_A4EPU1 Cluster: Putative hydrolase; n=2; Rhodobacterace... 60 1e-07
UniRef50_A0TTW8 Cluster: Nitrilase/cyanide hydratase and apolipo... 60 1e-07
UniRef50_Q9KE11 Cluster: BH1047 protein; n=1; Bacillus haloduran... 59 2e-07
UniRef50_Q89E80 Cluster: Bll7207 protein; n=1; Bradyrhizobium ja... 59 2e-07
UniRef50_Q6L0F7 Cluster: Carbon-nitrogen hydrolase family; n=2; ... 59 2e-07
UniRef50_A4SZC4 Cluster: Nitrilase/cyanide hydratase and apolipo... 58 4e-07
UniRef50_Q1AWK1 Cluster: Nitrilase/cyanide hydratase and apolipo... 58 5e-07
UniRef50_A4YP30 Cluster: N-carbamoyl-D-amino acid hydrolase; n=4... 58 5e-07
UniRef50_Q8ZVX6 Cluster: Nitrilase, conjectural; n=4; Pyrobaculu... 58 5e-07
UniRef50_A3TQB8 Cluster: Nitrilase/cyanide hydratase and apolipo... 57 7e-07
UniRef50_P46011 Cluster: Nitrilase 4; n=49; cellular organisms|R... 57 7e-07
UniRef50_Q2JDM2 Cluster: Nitrilase/cyanide hydratase and apolipo... 57 9e-07
UniRef50_Q0S9Y1 Cluster: Possible nitrilase; n=4; Actinomycetale... 57 9e-07
UniRef50_Q5WM18 Cluster: Methylthioribose recycling protein; n=2... 56 1e-06
UniRef50_Q2S2E4 Cluster: Hydrolase, carbon-nitrogen family; n=1;... 56 1e-06
UniRef50_A5V6Z2 Cluster: Nitrilase/cyanide hydratase and apolipo... 56 1e-06
UniRef50_Q2QQ94 Cluster: Hydrolase, carbon-nitrogen family prote... 56 1e-06
UniRef50_Q5KJU9 Cluster: Hydrolase, putative; n=1; Filobasidiell... 56 1e-06
UniRef50_A2BKF1 Cluster: Predicted amidohydrolase; n=1; Hyperthe... 56 1e-06
UniRef50_A5FKF8 Cluster: Nitrilase/cyanide hydratase and apolipo... 56 2e-06
UniRef50_A4SSL0 Cluster: Beta-ureidopropionase; n=1; Aeromonas s... 56 2e-06
UniRef50_A1IFF1 Cluster: Hydrolase, carbon-nitrogen family; n=1;... 56 2e-06
UniRef50_Q2LUZ0 Cluster: Carbon-nitrogen hydrolase family protei... 56 2e-06
UniRef50_A0RYH6 Cluster: Amidohydrolase; n=1; Cenarchaeum symbio... 56 2e-06
UniRef50_A5TTZ3 Cluster: Possible amidohydrolase; n=1; Fusobacte... 55 3e-06
UniRef50_P55176 Cluster: UPF0012 hydrolase in pqqF 5'region; n=1... 55 3e-06
UniRef50_Q8DCG5 Cluster: Predicted amidohydrolase; n=33; Gammapr... 55 4e-06
UniRef50_Q17CS4 Cluster: Nitrilase, putative; n=3; Culicidae|Rep... 55 4e-06
UniRef50_Q72HE8 Cluster: Beta-ureidopropionase; n=2; Thermus the... 54 5e-06
UniRef50_Q1PXD4 Cluster: Similar to N-carbamoyl-D-amino acid hyd... 54 6e-06
UniRef50_A3ZLM3 Cluster: Putative nitrilase; n=1; Blastopirellul... 54 6e-06
UniRef50_UPI0000D55F17 Cluster: PREDICTED: similar to CG7067-PA;... 54 8e-06
UniRef50_Q8KCC8 Cluster: Carbon-nitrogen hydrolase family protei... 54 8e-06
UniRef50_Q6N4F1 Cluster: Possible amidohydrolase; n=2; Rhodopseu... 54 8e-06
UniRef50_A0BR54 Cluster: Chromosome undetermined scaffold_122, w... 54 8e-06
UniRef50_O76463 Cluster: Nitrilase and fragile histidine triad f... 54 8e-06
UniRef50_A0L7H1 Cluster: Nitrilase/cyanide hydratase and apolipo... 53 1e-05
UniRef50_Q3IW15 Cluster: Predicted amidohydrolase; n=2; Rhodobac... 53 1e-05
UniRef50_Q2NTW0 Cluster: Putative uncharacterized protein; n=2; ... 53 1e-05
UniRef50_A4BQN0 Cluster: Nitrilase/cyanide hydratase and apolipo... 53 1e-05
UniRef50_A3LZY2 Cluster: Aliphatic nitrilase; n=1; Pichia stipit... 53 1e-05
UniRef50_A3CTE8 Cluster: Nitrilase/cyanide hydratase and apolipo... 53 1e-05
UniRef50_P58054 Cluster: UPF0012 hydrolase ybeM; n=33; Proteobac... 53 1e-05
UniRef50_Q1F028 Cluster: Nitrilase/cyanide hydratase and apolipo... 52 2e-05
UniRef50_A3EVA0 Cluster: NAD synthase; n=4; Bacteria|Rep: NAD sy... 52 2e-05
UniRef50_Q9LE50 Cluster: Nitrilase 1 like protein; n=2; Arabidop... 52 2e-05
UniRef50_Q47VH0 Cluster: Hydrolase, carbon-nitrogen family; n=1;... 52 3e-05
UniRef50_A4WA35 Cluster: Nitrilase/cyanide hydratase and apolipo... 52 3e-05
UniRef50_A0LH50 Cluster: Nitrilase/cyanide hydratase and apolipo... 52 3e-05
UniRef50_A5D6C3 Cluster: Putative uncharacterized protein; n=1; ... 51 4e-05
UniRef50_A4ALG5 Cluster: Putative hydrolase; n=2; Actinobacteria... 51 4e-05
UniRef50_P47016 Cluster: Probable hydrolase NIT2; n=6; Saccharom... 51 4e-05
UniRef50_A3HXT3 Cluster: Putative nitrilase; n=1; Algoriphagus s... 51 6e-05
UniRef50_A1SE99 Cluster: Nitrilase/cyanide hydratase and apolipo... 51 6e-05
UniRef50_A0U0W3 Cluster: Nitrilase/cyanide hydratase and apolipo... 51 6e-05
UniRef50_Q1MYM0 Cluster: Predicted amidohydrolase; n=1; Oceanoba... 50 8e-05
UniRef50_Q9HIW8 Cluster: Nitrilase related protein; n=2; Thermop... 50 8e-05
UniRef50_Q6JHR5 Cluster: Aliphatic amidase; n=1; Saccharopolyspo... 50 1e-04
UniRef50_Q0W654 Cluster: Putative amidohydrolase; n=1; unculture... 50 1e-04
UniRef50_P55175 Cluster: UPF0012 hydrolase sll0601; n=40; Cyanob... 50 1e-04
UniRef50_Q3A0A3 Cluster: Predicted amidohydrolase; n=1; Pelobact... 49 2e-04
UniRef50_A5WCY0 Cluster: Nitrilase/cyanide hydratase and apolipo... 49 2e-04
UniRef50_Q5R0H6 Cluster: Predicted amidohydrolase, nitrilase fam... 49 2e-04
UniRef50_Q3W243 Cluster: GCN5-related N-acetyltransferase:AIR sy... 49 2e-04
UniRef50_Q1LPP8 Cluster: Nitrilase/cyanide hydratase and apolipo... 49 2e-04
UniRef50_A6Q8M5 Cluster: Carbon-nitrogen hydrolase family protei... 49 2e-04
UniRef50_A3EPK6 Cluster: Putative carbon-nitrogen hydrolase; n=1... 49 2e-04
UniRef50_A0RNK8 Cluster: Hydrolase, carbon-nitrogen family; n=13... 49 2e-04
UniRef50_Q74FF8 Cluster: Hydrolase, carbon-nitrogen family; n=6;... 48 3e-04
UniRef50_Q127K6 Cluster: Nitrilase/cyanide hydratase and apolipo... 48 3e-04
UniRef50_A1SU00 Cluster: Nitrilase/cyanide hydratase and apolipo... 48 3e-04
UniRef50_Q0HEI5 Cluster: Nitrilase/cyanide hydratase and apolipo... 48 4e-04
UniRef50_A4BGL8 Cluster: Predicted amidohydrolase; n=1; Reinekea... 48 4e-04
UniRef50_Q8KFP8 Cluster: Carbon-nitrogen hydrolase family protei... 48 5e-04
UniRef50_Q4KB18 Cluster: Hydrolase, carbon-nitrogen family; n=2;... 48 5e-04
UniRef50_A0R400 Cluster: Hydrolase, carbon-nitrogen family prote... 48 5e-04
UniRef50_Q4Q8W4 Cluster: Nitrilase, putative; n=6; Trypanosomati... 48 5e-04
UniRef50_A1RZK0 Cluster: Nitrilase/cyanide hydratase and apolipo... 48 5e-04
UniRef50_Q30T00 Cluster: Nitrilase/cyanide hydratase and apolipo... 47 7e-04
UniRef50_A6X6J7 Cluster: Nitrilase/cyanide hydratase and apolipo... 47 7e-04
UniRef50_A5G317 Cluster: Nitrilase/cyanide hydratase and apolipo... 47 7e-04
UniRef50_Q82UY9 Cluster: Carbon-nitrogen hydrolase; n=50; Proteo... 47 0.001
UniRef50_Q28TG7 Cluster: Nitrilase/cyanide hydratase and apolipo... 47 0.001
UniRef50_A7FDR9 Cluster: Hydrolase, carbon-nitrogen family prote... 47 0.001
UniRef50_A4XN12 Cluster: Nitrilase/cyanide hydratase and apolipo... 47 0.001
UniRef50_A3Y529 Cluster: Putative uncharacterized protein; n=1; ... 47 0.001
UniRef50_Q23ND3 Cluster: Hydrolase, carbon-nitrogen family prote... 47 0.001
UniRef50_Q7WM47 Cluster: Putative uncharacterized protein; n=2; ... 46 0.001
UniRef50_Q7MQY7 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001
UniRef50_A0LQU6 Cluster: Nitrilase/cyanide hydratase and apolipo... 46 0.001
UniRef50_Q4WEA8 Cluster: Hydrolase, carbon-nitrogen family, puta... 46 0.001
UniRef50_A6SN02 Cluster: Nitrilase; n=3; Sclerotiniaceae|Rep: Ni... 46 0.001
UniRef50_Q8FM85 Cluster: Putative uncharacterized protein; n=2; ... 46 0.002
UniRef50_Q5NN79 Cluster: Nitrilase; n=17; Proteobacteria|Rep: Ni... 46 0.002
UniRef50_Q15ZG7 Cluster: Nitrilase/cyanide hydratase and apolipo... 46 0.002
UniRef50_Q5DC61 Cluster: SJCHGC06938 protein; n=1; Schistosoma j... 46 0.002
UniRef50_Q5C342 Cluster: SJCHGC04680 protein; n=1; Schistosoma j... 46 0.002
UniRef50_A2R283 Cluster: Contig An13c0120, complete genome; n=2;... 46 0.002
UniRef50_Q6RWQ5 Cluster: Nitrilase; n=1; uncultured organism|Rep... 46 0.002
UniRef50_Q60BT4 Cluster: Hydrolase, carbon-nitrogen family; n=15... 46 0.002
UniRef50_Q7QAW0 Cluster: ENSANGP00000011026; n=2; Culicidae|Rep:... 46 0.002
UniRef50_Q46AW4 Cluster: Putative amidohydrolase; n=1; Methanosa... 46 0.002
UniRef50_O25836 Cluster: Formamidase; n=17; Bacteria|Rep: Formam... 46 0.002
UniRef50_A5GU42 Cluster: Nitrilase-related protein; n=1; Synecho... 45 0.003
UniRef50_A4YSE7 Cluster: N-carbamoyl-D-amino acid hydrolase; n=1... 45 0.003
UniRef50_Q5K7Z3 Cluster: Expressed protein; n=1; Filobasidiella ... 45 0.003
UniRef50_A1CIE7 Cluster: Hydrolase, carbon-nitrogen family prote... 45 0.003
UniRef50_Q7UWX1 Cluster: Beta-alanine synthetase; n=1; Pirellula... 45 0.004
UniRef50_Q18UY7 Cluster: Nitrilase/cyanide hydratase and apolipo... 45 0.004
UniRef50_A6CFF3 Cluster: Putative nitrilase; n=1; Planctomyces m... 45 0.004
UniRef50_A3JKT7 Cluster: Acetyltransferase domain (GNAT family) ... 45 0.004
UniRef50_Q00Y86 Cluster: Carbon-nitrogen hydrolase; n=2; Ostreoc... 45 0.004
UniRef50_Q6KZW3 Cluster: Carbon-nitrogen hydrolase; n=1; Picroph... 45 0.004
UniRef50_UPI0000E472D9 Cluster: PREDICTED: similar to Ureidoprop... 44 0.005
UniRef50_Q4K4P2 Cluster: Hydrolase, carbon-nitrogen family; n=5;... 44 0.005
UniRef50_Q0VS65 Cluster: Carbon-nitrogen hydrolase family protei... 44 0.005
UniRef50_Q0LC17 Cluster: NAD+ synthetase; n=1; Herpetosiphon aur... 44 0.005
UniRef50_A0JW88 Cluster: Nitrilase/cyanide hydratase and apolipo... 44 0.005
UniRef50_Q88EJ9 Cluster: Carbon-nitrogen hydrolase family protei... 44 0.007
UniRef50_A6DN63 Cluster: Nitrilase/cyanide hydratase and apolipo... 44 0.007
UniRef50_A6DBX4 Cluster: Nitrilase/cyanide hydratase and apolipo... 44 0.007
UniRef50_A0LFW1 Cluster: Nitrilase/cyanide hydratase and apolipo... 44 0.007
UniRef50_Q6C005 Cluster: Similar to sp|P47016 Saccharomyces cere... 44 0.007
UniRef50_Q4P7D2 Cluster: Putative uncharacterized protein; n=1; ... 44 0.007
UniRef50_A7I641 Cluster: Nitrilase/cyanide hydratase and apolipo... 44 0.007
UniRef50_Q483K8 Cluster: Hydrolase, carbon-nitrogen family; n=1;... 44 0.009
UniRef50_Q16A64 Cluster: Hydrolase, putative; n=1; Roseobacter d... 44 0.009
UniRef50_Q0SBF1 Cluster: Probable nitrilase; n=2; Actinomycetale... 44 0.009
UniRef50_A6T2L9 Cluster: Nitrilase; n=1; Janthinobacterium sp. M... 44 0.009
UniRef50_A4XAH8 Cluster: Nitrilase/cyanide hydratase and apolipo... 44 0.009
UniRef50_Q81MJ4 Cluster: Hydrolase, carbon-nitrogen family; n=30... 43 0.012
UniRef50_A7I462 Cluster: Hydrolase in agr operon; n=1; Campyloba... 43 0.012
UniRef50_A6BC88 Cluster: Carbon-nitrogen hydrolase family protei... 43 0.012
UniRef50_A4EUM3 Cluster: Putative carbon-nitrogen hydrolase; n=2... 43 0.012
UniRef50_Q12ZA5 Cluster: Nitrilase/cyanide hydratase and apolipo... 43 0.012
UniRef50_P54608 Cluster: UPF0012 hydrolase yhcX; n=12; Bacteria|... 43 0.012
UniRef50_Q0S9R8 Cluster: Probable formamidase; n=1; Rhodococcus ... 43 0.016
UniRef50_A6T0X3 Cluster: Nitrilase; n=7; Bacteria|Rep: Nitrilase... 43 0.016
UniRef50_O94660 Cluster: Nitrilase; n=6; Ascomycota|Rep: Nitrila... 43 0.016
UniRef50_A3H5Q5 Cluster: Nitrilase/cyanide hydratase and apolipo... 43 0.016
UniRef50_Q6RWN7 Cluster: Nitrilase; n=21; root|Rep: Nitrilase - ... 42 0.021
UniRef50_Q8KFB2 Cluster: Carbon-nitrogen hydrolase family protei... 42 0.021
UniRef50_A6W7Y4 Cluster: Nitrilase/cyanide hydratase and apolipo... 42 0.021
UniRef50_A5V962 Cluster: Nitrilase/cyanide hydratase and apolipo... 42 0.021
UniRef50_A5AAF3 Cluster: Contig An02c0310, complete genome; n=5;... 42 0.021
UniRef50_A3DL17 Cluster: Nitrilase/cyanide hydratase and apolipo... 42 0.021
UniRef50_P82605 Cluster: Nitrilase; n=4; Bacteria|Rep: Nitrilase... 42 0.021
UniRef50_Q6RWP8 Cluster: Nitrilase; n=1; uncultured organism|Rep... 42 0.027
UniRef50_Q9ZJD8 Cluster: Putative; n=4; Helicobacter|Rep: Putati... 42 0.027
UniRef50_Q89XU5 Cluster: Amidohydrolase; n=48; Alphaproteobacter... 42 0.027
UniRef50_Q0UHH3 Cluster: Putative uncharacterized protein; n=1; ... 42 0.027
UniRef50_UPI000023E394 Cluster: hypothetical protein FG01991.1; ... 42 0.036
UniRef50_Q2RGR0 Cluster: Nitrilase/cyanide hydratase and apolipo... 42 0.036
UniRef50_A5FWH4 Cluster: Nitrilase/cyanide hydratase and apolipo... 42 0.036
UniRef50_Q9V1L5 Cluster: Amidohydrolase, putative; n=2; Thermoco... 42 0.036
UniRef50_A6QB76 Cluster: Hydrolase, carbon-nitrogen family; n=1;... 41 0.048
UniRef50_A4U2A6 Cluster: Nitrilase/cyanide hydratase and apolipo... 41 0.048
UniRef50_Q5ATG3 Cluster: Putative uncharacterized protein; n=3; ... 41 0.048
UniRef50_A4R649 Cluster: Putative uncharacterized protein; n=1; ... 41 0.048
UniRef50_A1D103 Cluster: Hydrolase, carbon-nitrogen family prote... 41 0.048
UniRef50_UPI0000E105FE Cluster: putative hydrolase, carbon-nitro... 41 0.063
UniRef50_O66508 Cluster: Putative uncharacterized protein; n=1; ... 41 0.063
UniRef50_Q2BKP4 Cluster: Putative carbon-nitrogen hydrolase; n=1... 41 0.063
UniRef50_Q11M91 Cluster: Nitrilase/cyanide hydratase and apolipo... 41 0.063
UniRef50_A3LY98 Cluster: Nitrilase superfamily member; n=3; Sacc... 41 0.063
UniRef50_Q6RWR2 Cluster: Nitrilase; n=1; uncultured organism|Rep... 40 0.083
UniRef50_Q6RWE5 Cluster: Nitrilase; n=4; root|Rep: Nitrilase - u... 40 0.083
UniRef50_Q7URE5 Cluster: Predicted amidohydrolase; n=1; Pirellul... 40 0.083
UniRef50_A2ICY3 Cluster: Cyanide hydratase; n=23; Gammaproteobac... 40 0.083
UniRef50_A1HU09 Cluster: Nitrilase/cyanide hydratase and apolipo... 40 0.083
UniRef50_A1HNR2 Cluster: Nitrilase/cyanide hydratase and apolipo... 40 0.083
UniRef50_A0Y2B3 Cluster: Putative hydrolase, carbon-nitrogen fam... 40 0.083
UniRef50_Q7VGG9 Cluster: Putative uncharacterized protein; n=1; ... 40 0.11
UniRef50_A3JK79 Cluster: Predicted amidohydrolase; n=3; Gammapro... 40 0.11
UniRef50_A1IFV0 Cluster: Putative hydrolase; n=1; Candidatus Des... 40 0.11
UniRef50_A0J1U1 Cluster: Nitrilase/cyanide hydratase and apolipo... 40 0.11
UniRef50_O76464 Cluster: Nitrilase and fragile histidine triad f... 40 0.11
UniRef50_UPI000023E628 Cluster: hypothetical protein FG00821.1; ... 40 0.15
UniRef50_Q1AZG5 Cluster: Nitrilase; n=1; Rubrobacter xylanophilu... 40 0.15
UniRef50_A6UC57 Cluster: Nitrilase/cyanide hydratase and apolipo... 40 0.15
UniRef50_A6Q4H3 Cluster: Hydrolase, carbon-nitrogen family; n=1;... 40 0.15
UniRef50_A5UTD2 Cluster: Nitrilase/cyanide hydratase and apolipo... 40 0.15
UniRef50_A1SV53 Cluster: Amidohydrolase-like protein; n=1; Psych... 39 0.19
UniRef50_Q8PXI9 Cluster: Nitrilase; n=3; Methanosarcina|Rep: Nit... 39 0.19
UniRef50_Q8NLZ3 Cluster: Predicted amidohydrolase; n=3; Coryneba... 39 0.25
UniRef50_Q4HN14 Cluster: Hydrolase, carbon-nitrogen family; n=2;... 39 0.25
UniRef50_Q0SAV3 Cluster: Probable nitrilase; n=1; Rhodococcus sp... 39 0.25
UniRef50_A3M2Z7 Cluster: Putative glutamine-dependent NAD(+) syn... 39 0.25
UniRef50_Q8Y8V0 Cluster: Lmo0792 protein; n=12; Listeria|Rep: Lm... 38 0.34
UniRef50_Q12DE7 Cluster: Nitrilase/cyanide hydratase and apolipo... 38 0.34
UniRef50_Q04W18 Cluster: Amidohydrolase; n=4; Leptospira|Rep: Am... 38 0.34
UniRef50_A6FJ09 Cluster: Putative hydrolase; n=1; Moritella sp. ... 38 0.34
UniRef50_Q8TLM7 Cluster: Carbon-nitrogen hydrolase; n=2; Methano... 38 0.34
UniRef50_A0R378 Cluster: Nitrilase 2; n=1; Mycobacterium smegmat... 38 0.44
UniRef50_UPI0000DAE70E Cluster: hypothetical protein Rgryl_01001... 38 0.59
UniRef50_Q97IH6 Cluster: Predicted amidohydrolase; n=1; Clostrid... 38 0.59
UniRef50_Q1MFH8 Cluster: Putative hydrolase; n=1; Rhizobium legu... 38 0.59
UniRef50_Q6AMZ4 Cluster: Putative uncharacterized protein; n=1; ... 37 0.77
UniRef50_A6W013 Cluster: Nitrilase/cyanide hydratase and apolipo... 37 0.77
UniRef50_A4CFA6 Cluster: Putative C-N hydrolase; superfamily UPF... 37 0.77
UniRef50_A0NZI0 Cluster: Nitrilase/cyanide hydratase and apolipo... 37 0.77
UniRef50_Q92DM8 Cluster: Lin0785 protein; n=5; Bacteria|Rep: Lin... 37 1.0
UniRef50_Q5LLB2 Cluster: Nitrilase family protein; n=7; Bacteria... 37 1.0
UniRef50_Q1GRP3 Cluster: Nitrilase/cyanide hydratase and apolipo... 37 1.0
UniRef50_Q1FPL1 Cluster: Nitrilase/cyanide hydratase and apolipo... 37 1.0
UniRef50_A1ZR32 Cluster: Hydrolase, carbon-nitrogen family; n=2;... 37 1.0
UniRef50_Q9PC24 Cluster: Probable glutamine-dependent NAD(+) syn... 37 1.0
UniRef50_Q2SQI0 Cluster: Predicted amidohydrolase; n=1; Hahella ... 36 1.4
UniRef50_A6F4Z1 Cluster: Predicted amidohydrolase; n=4; Gammapro... 36 1.4
UniRef50_A1B8M6 Cluster: Nitrilase/cyanide hydratase and apolipo... 36 1.4
UniRef50_Q6QDB8 Cluster: NIT4; n=2; Eukaryota|Rep: NIT4 - Vicia ... 36 1.4
UniRef50_Q6RWN4 Cluster: Nitrilase; n=6; root|Rep: Nitrilase - u... 36 1.8
UniRef50_Q0BS64 Cluster: Carbon-nitrogen hydrolase family protei... 36 1.8
UniRef50_A7ABL5 Cluster: Putative uncharacterized protein; n=2; ... 36 1.8
UniRef50_A6GKJ0 Cluster: Putative uncharacterized protein; n=1; ... 36 1.8
UniRef50_A0M3E2 Cluster: Carbon-nitrogen hydrolase; n=6; cellula... 36 1.8
UniRef50_Q5V604 Cluster: Nitrilase; n=2; Halobacteriaceae|Rep: N... 36 1.8
UniRef50_Q6RWS0 Cluster: Nitrilase; n=4; uncultured organism|Rep... 36 2.4
UniRef50_Q0EPQ3 Cluster: Nitrilase/cyanide hydratase and apolipo... 36 2.4
UniRef50_A7DA57 Cluster: Nitrilase/cyanide hydratase and apolipo... 36 2.4
UniRef50_A3SP65 Cluster: Possible nitrilase; n=2; Rhodobacterace... 36 2.4
UniRef50_A1I7L4 Cluster: Nitrilase/cyanide hydratase and apolipo... 36 2.4
UniRef50_A0CJZ7 Cluster: Chromosome undetermined scaffold_2, who... 36 2.4
UniRef50_Q5AHS1 Cluster: Potential N-terminal amidase; n=2; Cand... 36 2.4
UniRef50_Q5A428 Cluster: Nitrilase superfamily protein; n=2; Sac... 36 2.4
UniRef50_Q8TPH5 Cluster: Carbon-nitrogen hydrolase; n=1; Methano... 36 2.4
UniRef50_Q6MPB5 Cluster: Putative amidohydrolase; n=1; Bdellovib... 35 3.1
UniRef50_P73046 Cluster: Sll1640 protein; n=1; Synechocystis sp.... 35 3.1
UniRef50_A0H2F4 Cluster: Nitrilase/cyanide hydratase and apolipo... 35 3.1
UniRef50_Q9X0Y0 Cluster: Probable glutamine-dependent NAD(+) syn... 35 3.1
UniRef50_Q6RWG5 Cluster: Nitrilase; n=2; uncultured organism|Rep... 35 4.1
UniRef50_Q5PMN3 Cluster: Possible hydrolase; n=4; Salmonella|Rep... 35 4.1
UniRef50_Q2CBA1 Cluster: Putative amidohydrolase; n=1; Oceanicol... 35 4.1
UniRef50_A0R703 Cluster: Hydrolase, carbon-nitrogen family prote... 35 4.1
UniRef50_A0J1T6 Cluster: Nitrilase/cyanide hydratase and apolipo... 35 4.1
UniRef50_P40447 Cluster: Putative nitrilase-like protein NIT1; n... 35 4.1
UniRef50_UPI00015A73E8 Cluster: UPI00015A73E8 related cluster; n... 34 5.5
UniRef50_Q7MUX3 Cluster: Hydrolase, carbon-nitrogen family; n=1;... 34 5.5
UniRef50_Q1QW55 Cluster: Nitrilase/cyanide hydratase and apolipo... 34 5.5
UniRef50_Q15YJ8 Cluster: Succinylglutamate desuccinylase/asparto... 34 5.5
UniRef50_A6VWN8 Cluster: Nitrilase/cyanide hydratase and apolipo... 34 5.5
UniRef50_Q9Y9L1 Cluster: Putative hydrolase; n=1; Aeropyrum pern... 34 5.5
UniRef50_Q8F0N0 Cluster: Carbon-nitrogen hydrolase; n=16; Bacter... 34 7.2
UniRef50_Q2ADS5 Cluster: Nitrilase/cyanide hydratase and apolipo... 34 7.2
UniRef50_A6V5Q2 Cluster: Nitrilase 4; n=2; Bacteria|Rep: Nitrila... 34 7.2
UniRef50_Q2TYD8 Cluster: Carbon-nitrogen hydrolase; n=1; Aspergi... 34 7.2
UniRef50_Q4J710 Cluster: Putative uncharacterized protein; n=1; ... 34 7.2
UniRef50_Q87T64 Cluster: Putative amidohydrolase; n=2; Vibrio pa... 33 9.5
UniRef50_P72907 Cluster: Slr1071 protein; n=1; Synechocystis sp.... 33 9.5
UniRef50_O31664 Cluster: YkrU protein; n=5; Bacilli|Rep: YkrU pr... 33 9.5
UniRef50_A4C8B3 Cluster: Sensor protein; n=1; Pseudoalteromonas ... 33 9.5
UniRef50_A4AR83 Cluster: Apolipoprotein N-acyltransferase; n=1; ... 33 9.5
UniRef50_A1ICC8 Cluster: YhcX; n=1; Candidatus Desulfococcus ole... 33 9.5
UniRef50_A4R5F2 Cluster: Putative uncharacterized protein; n=1; ... 33 9.5
>UniRef50_Q6NP10 Cluster: LD13390p; n=7; Eukaryota|Rep: LD13390p -
Drosophila melanogaster (Fruit fly)
Length = 408
Score = 537 bits (1325), Expect = e-151
Identities = 248/383 (64%), Positives = 298/383 (77%)
Query: 1 MASAELTSLDEVISNSLKGKELEEFNRIHYGRIDQCALFISSVAAQKAASNGFEIKAYDF 60
M++ EL +L++ + L EL+E RI YG + L + + A A NGF+IK Y F
Sbjct: 23 MSAFELKNLNDCLEKHLPPDELKEVKRILYGVEEDQTLELPTSAKDIAEQNGFDIKGYRF 82
Query: 61 PARKEECRKPRIVRLGLIQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQE 120
AR+E+ RK RIVR+G IQ+SI I T PI +QR AI+ KV+ +I AAA NI+C QE
Sbjct: 83 TAREEQTRKRRIVRVGAIQNSIVIPTTAPIEKQREAIWNKVKTMIKAAAEAGCNIVCTQE 142
Query: 121 AWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWN 180
AW MPFAFCTREK PWC+FAE GP+T LAELA Y+MVII ILERD HG+TIWN
Sbjct: 143 AWTMPFAFCTREKFPWCEFAEEAENGPTTKMLAELAKAYNMVIIHSILERDMEHGETIWN 202
Query: 181 TAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHP 240
TAVVI+ G+ +GKHRKNHIPRVGDFNESTYY EGNTGHPVFET++GK+A+NICYGRHHP
Sbjct: 203 TAVVISNSGRYLGKHRKNHIPRVGDFNESTYYMEGNTGHPVFETEFGKLAVNICYGRHHP 262
Query: 241 LNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFT 300
NW+MFG+NGAEIVFNPSAT+ LSE LW++EARNAAIANSY+T INRVGTE FPNE+T
Sbjct: 263 QNWMMFGLNGAEIVFNPSATIGRLSEPLWSIEARNAAIANSYFTVPINRVGTEQFPNEYT 322
Query: 301 SGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMT 360
SGDG AHK+FG FYGSSYV APDGSRTP LSR KDGLL+ ++DLNLCRQ+KD WGF MT
Sbjct: 323 SGDGNKAHKEFGPFYGSSYVAAPDGSRTPSLSRDKDGLLVVELDLNLCRQVKDFWGFRMT 382
Query: 361 QRLDLYAQSLNEAIKHDYVPQVV 383
QR+ LYA+S +A +H + PQ++
Sbjct: 383 QRVPLYAESFKKASEHGFKPQII 405
>UniRef50_Q9UBR1 Cluster: Beta-ureidopropionase; n=42; root|Rep:
Beta-ureidopropionase - Homo sapiens (Human)
Length = 384
Score = 508 bits (1254), Expect = e-143
Identities = 228/383 (59%), Positives = 290/383 (75%), Gaps = 1/383 (0%)
Query: 1 MASAELTSLDEVISNSLKGKELEEFNRIHYGRIDQCALFISSVAAQKAASNGFEIKAYDF 60
MA AE SL+E + L +L+E R+ YG+ + L + A + A+ FE++ Y F
Sbjct: 1 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGK-ELRKLDLPREAFEAASREDFELQGYAF 59
Query: 61 PARKEECRKPRIVRLGLIQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQE 120
A +E+ R+PRIV +GL+Q+ I + + P+ +Q A+ +++ I+ AA VNI+C QE
Sbjct: 60 EAAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQE 119
Query: 121 AWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWN 180
AW MPFAFCTREK PW +FAE GP+T F +LA +DMV++SPILERD HGD +WN
Sbjct: 120 AWTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWN 179
Query: 181 TAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHP 240
TAVVI+ G V+GK RKNHIPRVGDFNESTYY EGN GHPVF+T++G++A+NICYGRHHP
Sbjct: 180 TAVVISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHP 239
Query: 241 LNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFT 300
LNWLM+ INGAEI+FNPSAT+ LSE LW +EARNAAIAN +TCAINRVGTE FPNEFT
Sbjct: 240 LNWLMYSINGAEIIFNPSATIGALSESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFT 299
Query: 301 SGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMT 360
SGDGK AH+DFG+FYGSSYV APD SRTPGLSR +DGLL+A++DLNLC+Q+ D W F MT
Sbjct: 300 SGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMT 359
Query: 361 QRLDLYAQSLNEAIKHDYVPQVV 383
R ++YA+ L EA+K +Y P +V
Sbjct: 360 GRYEMYARELAEAVKSNYSPTIV 382
>UniRef50_UPI0000DC0724 Cluster: ureidopropionase, beta; n=1; Rattus
norvegicus|Rep: ureidopropionase, beta - Rattus
norvegicus
Length = 392
Score = 412 bits (1015), Expect = e-114
Identities = 193/383 (50%), Positives = 263/383 (68%), Gaps = 2/383 (0%)
Query: 1 MASAELTSLDEVISNSLKGKELEEFNRIHYGRIDQCALFISSVAAQKAASNGFEIKAYDF 60
MA E SL++ + L +L + RI YG+ + L + A + A+ FE+K Y F
Sbjct: 1 MAGPEWQSLEQCLEKHLPPDDLSQVKRILYGKQTR-NLDLPRKALEAASERNFELKGYAF 59
Query: 61 PARKEECRKPRIVRLGLIQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQE 120
A KE+ R P+IVR+GL+Q+ I + T P+ +Q A+ +++++I AA VNI+C QE
Sbjct: 60 GAAKEQQRCPQIVRVGLVQNRIPLPTSAPVAEQVSALHKRIEEIAEVAAMCGVNIICFQE 119
Query: 121 AWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWN 180
AWNMPFAFCTREK PW +FAE G +T F + ++ + +I+ L + G WN
Sbjct: 120 AWNMPFAFCTREKLPWTEFAESAEDGLTTRFCQKGKFQHIVCLIAIFLRQSLTLGLVAWN 179
Query: 181 TAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHP 240
+ + G V + + H P + D++ STYY EGN GHPVF+T++G++A+NICYGRHHP
Sbjct: 180 SLDISVNAGLVNARFKDVHHPVI-DYSYSTYYMEGNLGHPVFQTQFGRIAVNICYGRHHP 238
Query: 241 LNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFT 300
LNWLM+ +NGAEI+FNPSAT+ LSE +W +EARNAAIAN +TCA+NRVG E +PNEFT
Sbjct: 239 LNWLMYSVNGAEIIFNPSATIGELSESMWPIEARNAAIANHCFTCALNRVGQEHYPNEFT 298
Query: 301 SGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMT 360
SGDGK AH D G+FYGSSYV APDG RTPGLSR +D LL+ +++LNLC+QI D W F MT
Sbjct: 299 SGDGKKAHHDLGYFYGSSYVAAPDGRRTPGLSRNQDRLLVTELNLNLCQQINDFWTFKMT 358
Query: 361 QRLDLYAQSLNEAIKHDYVPQVV 383
RL++YA+ L EA+K +Y P +V
Sbjct: 359 GRLEMYARELAEAVKPNYSPNIV 381
>UniRef50_A7SG03 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 359
Score = 372 bits (914), Expect = e-101
Identities = 187/383 (48%), Positives = 250/383 (65%), Gaps = 29/383 (7%)
Query: 3 SAELTSLDEVISNSLKGKELEEFNRIHYGRIDQCALFISSVAAQKAASNGFEIKAYDFPA 62
+AE SL++ + +L ++L+E RI YG L + + A AA FE+ Y A
Sbjct: 2 AAEFESLNKTLEKNLPAEDLKEVKRILYGN-PVSDLSLPAAAVSVAAELDFELAGYKIDA 60
Query: 63 RKEECRKPRIVRLGLIQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQEAW 122
EE R+PR+VR+G +Q+ I T+ PI +QR + +++ I+ AAA +VN++C QE W
Sbjct: 61 AAEELRQPRLVRIGAVQNKIVEPTNMPIAKQREGLHNRMKDIVKAAALSKVNVICFQECW 120
Query: 123 NMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTA 182
MPFAFCTREKQPW +FAE GP+ E A +Y+MVI+SPILERD H + +WNTA
Sbjct: 121 TMPFAFCTREKQPWTEFAESAEDGPTVRLCQEWAKRYNMVIVSPILERDHTHQEILWNTA 180
Query: 183 VVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLN 242
V+I+ G+VIGK RKNHIPRVGDFNESTYY EG+ GH VF+T++ GR ++
Sbjct: 181 VIISNTGEVIGKTRKNHIPRVGDFNESTYYMEGDMGHQVFQTQFDT-------GR---IS 230
Query: 243 WLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSG 302
W + + G+ + L E LW++EARNAAIANSY+T INRVGT S E
Sbjct: 231 WFLVSLQGSHYIL----VALHLCEPLWSIEARNAAIANSYFTVPINRVGTASILEE---- 282
Query: 303 DGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQR 362
P SSYV AP+GSRTPGLSR +DGLL+ +VDLNLCRQ+KDKWGF MT R
Sbjct: 283 -NNPR---------SSYVAAPNGSRTPGLSRTRDGLLVTEVDLNLCRQVKDKWGFQMTSR 332
Query: 363 LDLYAQSLNEAIKHDYVPQVVHK 385
L++YA+SL+EA++ +Y P +VH+
Sbjct: 333 LEMYAKSLSEAVQRNYEPPIVHE 355
>UniRef50_Q5L031 Cluster: Beta-alanine synthase; n=19; Bacteria|Rep:
Beta-alanine synthase - Geobacillus kaustophilus
Length = 296
Score = 212 bits (517), Expect = 2e-53
Identities = 119/302 (39%), Positives = 170/302 (56%), Gaps = 22/302 (7%)
Query: 73 VRLGLIQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTRE 132
V +GLIQ S + D P+ + EK K++ A I+CLQE + P+ FC +
Sbjct: 5 VTIGLIQASHNVHGDEPVEVHKEKAIEKHVKLVKEAKDRGAQIICLQEIFYGPY-FCAEQ 63
Query: 133 KQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVI 192
W + AE + GP+T E+A + +VI+ PI ER+ I T +NTA VI+ G +
Sbjct: 64 NTKWYEAAEEIPNGPTTKMFQEIAKQLGVVIVLPIYEREGIA--TYYNTAAVIDADGTYL 121
Query: 193 GKHRKNHIPRVGDFNEST-----YYFE-GNTGHPVFETKYGKVAINICYGRHHPLNWLMF 246
GK+RK HIP VG NE +YF+ GN G+ VF+T + K+ + ICY RH P +
Sbjct: 122 GKYRKQHIPHVGVGNEGCGFWEKFYFKPGNLGYSVFDTAFAKIGVYICYDRHFPEGARIL 181
Query: 247 GINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKP 306
G+ GAEIVFNPSATV+GLSE+LW +E A+AN YY AINRVG E
Sbjct: 182 GLKGAEIVFNPSATVAGLSEYLWKLEQPAHAVANGYYVAAINRVGYE------------- 228
Query: 307 AHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
A + G FYG SY+ P G+ SR +D ++I ++ + R+++D W F +R + Y
Sbjct: 229 APWNMGEFYGQSYLVDPRGNFVAMGSRDQDEVVIGVMNKKMIREVRDIWQFYRDRRPETY 288
Query: 367 AQ 368
++
Sbjct: 289 SE 290
>UniRef50_O61697 Cluster: Putative beta-ureidopropionase; n=1;
Manduca sexta|Rep: Putative beta-ureidopropionase -
Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm)
Length = 185
Score = 205 bits (500), Expect = 2e-51
Identities = 97/167 (58%), Positives = 125/167 (74%), Gaps = 4/167 (2%)
Query: 5 ELTSLDEVISNSLKGKELEEFNRIHYGRIDQCALFI--SSVAAQKAASNGFEIKAYDFPA 62
E SL+ +I N+L G++L+EFNRI+YGR + + + SS+AA K A FE+ AY FPA
Sbjct: 3 ETQSLEAIIENNLSGRDLDEFNRIYYGRKNHLEVKLKDSSLAAAKEAD--FEVAAYAFPA 60
Query: 63 RKEECRKPRIVRLGLIQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQEAW 122
+KE+ R PRIV++G+IQHSI TD P+ +Q+ AIF+KV+KII A E VNI+C QE W
Sbjct: 61 KKEQTRPPRIVKVGVIQHSIGAPTDRPVNEQKKAIFDKVKKIIDVAGQEGVNIICFQELW 120
Query: 123 NMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILE 169
NMPFAFCTREKQPWC+FAE GP+T FL ELA+KY MVI+S IL+
Sbjct: 121 NMPFAFCTREKQPWCEFAESAEEGPTTRFLRELAMKYSMVIVSSILD 167
>UniRef50_Q1IQA8 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=52; Bacteria|Rep:
Nitrilase/cyanide hydratase and apolipoprotein
N-acyltransferase - Acidobacteria bacterium (strain
Ellin345)
Length = 303
Score = 125 bits (301), Expect = 2e-27
Identities = 86/303 (28%), Positives = 145/303 (47%), Gaps = 26/303 (8%)
Query: 75 LGLIQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQ 134
+GLIQ S P+ ++ +A K + AA + ++CL E + + FC RE
Sbjct: 8 IGLIQMSCG-----PVPEENMA---KALDRVRDAAKQGATVICLPELFQTQY-FCQREDT 58
Query: 135 PWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGK 194
+ AE + GP+T + +LA + +V+++ + ER NTA +++E G + G
Sbjct: 59 ALFELAESI-PGPATKKMGDLARELGVVVVASLFERRA--PGLYHNTAAILDEAGALKGI 115
Query: 195 HRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIV 254
+RK HIP + E Y+ G+ G FETK+G + +C+ + +P + + GA+++
Sbjct: 116 YRKMHIPDDPLYYEKYYFTPGDLGFKTFETKFGPIGTLVCWDQWYPEGARLTALQGAQVL 175
Query: 255 FNPSA--------TVSGLSEH-LWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGK 305
F P+A G S+H W R+ AIAN Y +NRVG E+ G
Sbjct: 176 FYPTAIGWHPAEKAEFGESQHDAWRTIQRSHAIANGVYVGVVNRVG-----KEYGDIRGN 230
Query: 306 PAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDL 365
A F+G S++ P G S K+ +L+A +D+ ++ W F +R+D
Sbjct: 231 RAEGAGLEFWGGSFIADPFGQVIAEASHDKEEILLADIDVKRMEDVRRNWPFLRDRRIDS 290
Query: 366 YAQ 368
Y +
Sbjct: 291 YGK 293
>UniRef50_Q97RA3 Cluster: Carbon-nitrogen hydrolase family protein;
n=24; Bacteria|Rep: Carbon-nitrogen hydrolase family
protein - Streptococcus pneumoniae
Length = 291
Score = 118 bits (283), Expect = 3e-25
Identities = 78/275 (28%), Positives = 132/275 (48%), Gaps = 13/275 (4%)
Query: 99 EKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVK 158
+ ++++ AA + I+ L E + P+ FC + + +A+ V + +A +
Sbjct: 22 QTAERLVRQAAEQGAQIILLPELFEHPY-FCQERQYDYYQYAQSVAENTAIQHFKVIAKE 80
Query: 159 YDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTG 218
+V+ E+D G+ ++N+ VI+ G+V+G +RK HIP + E Y+ GNTG
Sbjct: 81 LQVVLPISFYEKD---GNVLYNSIAVIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTG 137
Query: 219 HPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGL-----SEHLWAVEA 273
V+ T+Y K+ I IC+ + P +NGAE++F P+A S S W
Sbjct: 138 FKVWNTRYAKIGIGICWDQWFPETARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTM 197
Query: 274 RNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSR 333
+ A AN A NR G E +G G+ + D FYGSS++T G+ R
Sbjct: 198 QGHAAANIVPVIAANRYGLEEVTPSEENG-GQSSSLD---FYGSSFMTDETGAILERAER 253
Query: 334 IKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLYAQ 368
++ +L+A DL+ + WG +R ++Y Q
Sbjct: 254 QEEAVLLATYDLDKGASERLNWGLFRDRRPEMYRQ 288
>UniRef50_Q9ABL5 Cluster: Hydrolase, carbon-nitrogen family; n=13;
Bacteria|Rep: Hydrolase, carbon-nitrogen family -
Caulobacter crescentus (Caulobacter vibrioides)
Length = 292
Score = 113 bits (271), Expect = 1e-23
Identities = 81/277 (29%), Positives = 132/277 (47%), Gaps = 19/277 (6%)
Query: 96 AIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAEL 155
A +K + I AA++ ++ E + P+ FC +++ W A P P +A L
Sbjct: 20 ANIKKTEGFIREAASKGAQVILPSELFQGPY-FCVAQEERWFAQAHPWREHPVVKAIAPL 78
Query: 156 AVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEG 215
A + +VI I ER+ H +N+ V+ + G ++G +RK+HIP + E Y+ G
Sbjct: 79 AGELGVVIPISIFEREGPH---YFNSLVMADADGSLMGVYRKSHIPDGPGYMEKYYFRPG 135
Query: 216 NTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVS-----GLSEHL-W 269
+TG V++T++G++ + IC+ + +P + GAE +F P+A S L L W
Sbjct: 136 DTGFKVWDTRFGRIGVGICWDQWYPECARAMALMGAEALFYPTAIGSEPHDASLDTALPW 195
Query: 270 AVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTP 329
+ A++N NR+G E + DG P FYGSS+V G
Sbjct: 196 RRAMQGHAVSNVIPVIGANRIGFEPW-------DGYP--NGGQTFYGSSFVADHRGDLVS 246
Query: 330 GLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
L R +GL+ A DL+ + WGF +R +LY
Sbjct: 247 ELGRADEGLVSATFDLDFLTTHRAAWGFFRDRRPELY 283
>UniRef50_A7I5W9 Cluster: Porphyromonas-type peptidyl-arginine
deiminase; n=1; Candidatus Methanoregula boonei 6A8|Rep:
Porphyromonas-type peptidyl-arginine deiminase -
Methanoregula boonei (strain 6A8)
Length = 640
Score = 110 bits (264), Expect = 7e-23
Identities = 97/321 (30%), Positives = 142/321 (44%), Gaps = 42/321 (13%)
Query: 75 LGLIQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQ 134
+ LIQ I D + + R E+V+K AA +CL E + + F +
Sbjct: 8 IALIQMEIGPDPDRNLNEAR----ERVEK----AAQNGAQFICLPELFRTRY-FPQQIGT 58
Query: 135 PWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGK 194
P AE + G ST +A +Y VII P+ ER + + N AVVI+ G +
Sbjct: 59 PVQSLAETI-PGESTDVFTRIAKEYKAVIIVPVFERSPL--GHLENAAVVIDADGSLHAP 115
Query: 195 HRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIV 254
+ K HIP+ F E Y++ GN + V T+YGK+A+ ICY + P + GAEI+
Sbjct: 116 YYKVHIPQDPKFFEKGYFYPGNH-YAVHATRYGKIAVLICYDQWFPEAARCVSLEGAEII 174
Query: 255 FNPSATVSGLSE--------HLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKP 306
F P+A + +E W + R+ AIANS + A+NR G G+G
Sbjct: 175 FYPTAIGNPCTEQPSEGDWQEAWEIIQRSHAIANSVHIAAVNRAG----------GEGNI 224
Query: 307 AHKDFGHFYGSSYVTAPDGSRTPGLSRIKDG--LLIAQVDLNLCRQIKDKWGFTMTQRLD 364
F+G S++ G L+R D + A DL L I+D WGF +R D
Sbjct: 225 ------RFFGGSFICDAFGK---VLARAGDANETITATADLELNESIRDSWGFFRNRRPD 275
Query: 365 LYAQSLNEAIKHDYVPQVVHK 385
Y +HD + K
Sbjct: 276 TYGAVCARVPEHDATAPIPRK 296
>UniRef50_Q8VYF5 Cluster: N-carbamoylputrescine amidase; n=60;
cellular organisms|Rep: N-carbamoylputrescine amidase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 326
Score = 110 bits (264), Expect = 7e-23
Identities = 79/270 (29%), Positives = 131/270 (48%), Gaps = 20/270 (7%)
Query: 104 IISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVI 163
++ A A+ NI+ +QE + + FC +++ + A+P P+ + +LA + +VI
Sbjct: 60 LVREAHAKGANIILIQELFE-GYYFCQAQREDFFKRAKPYKNHPTIARMQKLAKELGVVI 118
Query: 164 -ISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVF 222
+S E + H +N+ +I+ G +G +RK+HIP + E Y+ G+TG VF
Sbjct: 119 PVSFFEEANTAH----YNSIAIIDADGTDLGIYRKSHIPDGPGYQEKFYFNPGDTGFKVF 174
Query: 223 ETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVS-----GL-SEHLWAVEARNA 276
+TK+ K+ + IC+ + P + GAEI+F P+A S GL S W +
Sbjct: 175 QTKFAKIGVAICWDQWFPEAARAMVLQGAEILFYPTAIGSEPQDQGLDSRDHWRRVMQGH 234
Query: 277 AIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKD 336
A AN A NR+G E E G + FYG+S++ P G +
Sbjct: 235 AGANVVPLVASNRIGKEIIETE--HGPSQIT------FYGTSFIAGPTGEIVAEADDKSE 286
Query: 337 GLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
+L+AQ DL++ + + WG +R DLY
Sbjct: 287 AVLVAQFDLDMIKSKRQSWGVFRDRRPDLY 316
>UniRef50_A6DKQ0 Cluster: Carbon-nitrogen hydrolase family protein;
n=1; Lentisphaera araneosa HTCC2155|Rep: Carbon-nitrogen
hydrolase family protein - Lentisphaera araneosa
HTCC2155
Length = 286
Score = 109 bits (261), Expect = 2e-22
Identities = 83/282 (29%), Positives = 135/282 (47%), Gaps = 29/282 (10%)
Query: 103 KIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMV 162
K+I+ AA NI+C QE + + FC + +A+ + F + A + +V
Sbjct: 24 KLIADAAKSGANIICTQELFLSNY-FCREQNTEHFQYAQKIDQELLADF-QQCAKNHGVV 81
Query: 163 IISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVF 222
+ E + ++G +NT+V+I+ G +GK+RK HIP+ F E Y+ GN G PVF
Sbjct: 82 LALSFFE-EALNG-VYYNTSVIIDADGTYLGKYRKLHIPQDPYFEEKFYFTPGNLGVPVF 139
Query: 223 ETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSA--------TVSGLSE-HLWAVEA 273
ET++GK+++ IC+ + P + + GAEI+ P+A G + H W
Sbjct: 140 ETQFGKISLIICWDQWFPETARLACLAGAEIILVPTAIGWLPDEKEEHGAQQAHSWTQVQ 199
Query: 274 RNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSR 333
A+AN Y A+NRVG E +P F+G S+++ G S
Sbjct: 200 LGHAVANGCYYAAVNRVGIE-----------EPI-----QFWGQSFISDFYGQTLAQASS 243
Query: 334 IKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLYAQSLNEAIK 375
++ +L A +DL R+ + W F +R+D Y Q AI+
Sbjct: 244 NEEEILFADLDLKQLREHRQIWPFFRDRRIDAYDQLKLRAIE 285
>UniRef50_A4B9A7 Cluster: Probable hydratase; n=2; Bacteria|Rep:
Probable hydratase - Reinekea sp. MED297
Length = 289
Score = 108 bits (260), Expect = 2e-22
Identities = 73/271 (26%), Positives = 125/271 (46%), Gaps = 22/271 (8%)
Query: 102 QKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDM 161
++++ AAA ++ LQE + P+ FC +K+ + FA + P+ A +A + +
Sbjct: 25 ERLVREAAASGAQVILLQELFERPY-FCQHQKEEFRRFATAIDDNPAIAHFAPIARELGV 83
Query: 162 VIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPV 221
V+ E+ G +N+ VV++ G+ +G +RK HIP + E Y+ G+TG V
Sbjct: 84 VLPISFFEQC---GPVAYNSVVVLDADGENLGLYRKTHIPDGPGYCEKFYFTPGDTGFQV 140
Query: 222 FETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGL------SEHLWAVEARN 275
F T++G++ + IC+ + P + GAE++F P+A S S W +
Sbjct: 141 FSTRFGRIGVGICWDQWFPETARAMTLMGAELLFYPTAIGSEPYNPDIDSSGHWQRTQQG 200
Query: 276 AAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIK 335
A AN A NR+GTE + + FYGSS++ G+ + R
Sbjct: 201 HAAANVIPLIASNRIGTEVIDDTQIT------------FYGSSFIADNTGALVTSMDRTS 248
Query: 336 DGLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
G + A DL+ + +WG +R Y
Sbjct: 249 TGFIQATFDLDALNAQRSEWGLFRDRRPSQY 279
>UniRef50_Q1GTC5 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=9; Bacteria|Rep:
Nitrilase/cyanide hydratase and apolipoprotein
N-acyltransferase - Sphingopyxis alaskensis
(Sphingomonas alaskensis)
Length = 300
Score = 107 bits (256), Expect = 6e-22
Identities = 76/278 (27%), Positives = 126/278 (45%), Gaps = 26/278 (9%)
Query: 101 VQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYD 160
V ++ AAAA I+ E + P+ FC E++ A P PS V + LA K
Sbjct: 42 VTALVEAAAARGAQIILPPELFEGPY-FCQVEEEELFATARPTAEHPSVVAMQALAAKCK 100
Query: 161 MVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHP 220
+ I + ERD H +NT +I G ++G +RK+HIP + E Y+ GNTG
Sbjct: 101 VAIPTSFFERDGHH---YYNTLAMIGPDGGIMGTYRKSHIPDGPGYEEKYYFRPGNTGFK 157
Query: 221 VFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGL------SEHLWAVEAR 274
++E ++ + +C+ + +P + GAE++F P+A S + +W +
Sbjct: 158 IWEVFDTRIGVGVCWDQWYPECARAMALMGAELLFYPTAIGSEPYDADLDTSRMWRRAMQ 217
Query: 275 NAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRI 334
A++N A NR+GTE GD + FYG S++ G T
Sbjct: 218 GHAVSNCMPVIAANRIGTE--------GDAR--------FYGHSFIADEWGDLTQAFGAS 261
Query: 335 KDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLYAQSLNE 372
+ G L+ +DL+ + + GF +R LY + + +
Sbjct: 262 ETGALVETIDLDRAAKHRAGMGFFRDRRPQLYGRLVED 299
>UniRef50_Q2S196 Cluster: Hydrolase, carbon-nitrogen family; n=1;
Salinibacter ruber DSM 13855|Rep: Hydrolase,
carbon-nitrogen family - Salinibacter ruber (strain DSM
13855)
Length = 283
Score = 105 bits (251), Expect = 3e-21
Identities = 82/296 (27%), Positives = 142/296 (47%), Gaps = 32/296 (10%)
Query: 75 LGLIQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPF---AFCTR 131
+ L+QH+++ P + R+ ++ + + AAA +++ E PF
Sbjct: 3 IALVQHAVS-----PASPPRV---DRGVRAVQAAADAGADLVVFPELSFTPFYPRVPVAE 54
Query: 132 EKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKV 191
++ D AEPV GP+T LAE A +V++ ++ERD G+ ++T+ V++ G +
Sbjct: 55 RRRSARDLAEPV-PGPTTEALAEAAADGGVVVVFNLMERD---GERTFDTSPVLDADGTL 110
Query: 192 IGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGA 251
+G+ R HI +F+E YY G+TG PV++T G++ + +CY RH+P + A
Sbjct: 111 LGRTRMMHITAYENFHEQGYYDPGDTGAPVYDTAAGRIGVAVCYDRHYPEYLRALALQDA 170
Query: 252 EIVFNPSA-TVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKD 310
++V P A TV + ++ E R AA+ + ++ NR G E GD +
Sbjct: 171 DLVVVPQAGTVGEWPDGMYEAELRVAALQHGFFAALANRTGPE--------GDMQ----- 217
Query: 311 FGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
F G S+VT P G ++ +L A +DL+ + F +R D Y
Sbjct: 218 ---FAGRSFVTDPFGEVVAQAPGAEETILHASLDLSRTADAPARRLFLRHRRPDQY 270
>UniRef50_Q972L1 Cluster: 281aa long hypothetical
beta-ureidopropionase; n=1; Sulfolobus tokodaii|Rep:
281aa long hypothetical beta-ureidopropionase -
Sulfolobus tokodaii
Length = 281
Score = 101 bits (242), Expect = 3e-20
Identities = 79/277 (28%), Positives = 128/277 (46%), Gaps = 20/277 (7%)
Query: 92 QQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVF 151
+ + A +K + AA + ++ E + + F E + D AEP GP+
Sbjct: 16 ESKEANIQKALEYTKAAVKDGAELIVYNELFTTQY-FPATEDPKFFDLAEPE-DGPTVRV 73
Query: 152 LAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTY 211
AE + +Y + +I I E D ++TA+ I + GKV+GK+RK HIP+V + E +
Sbjct: 74 FAEFSKQYKIGMIITIFEEDKKIKGIYYDTAIFIKD-GKVLGKYRKTHIPQVPGYYEK-F 131
Query: 212 YFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAV 271
YF+ +PVF+ K+ ICY RH P + + GA+IV P T + W +
Sbjct: 132 YFKPGKEYPVFDFGGYKIGAVICYDRHFPEGVRILTLKGADIVTIP--TTTNFYPETWEL 189
Query: 272 EARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGL 331
E R A N+ Y +NR P F GK ++G S V P G+ +
Sbjct: 190 ELRAHAAFNTIYVVGVNRT-----PEIF---QGKEI-----DYFGKSLVADPTGNILKEM 236
Query: 332 SRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLYAQ 368
S ++G I V+L+ R+ + K F ++ + Y +
Sbjct: 237 SS-QEGYEIVDVNLDFIRERRKKAPFLRDRKPENYTE 272
>UniRef50_A4J4S3 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Desulfotomaculum
reducens MI-1|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Desulfotomaculum
reducens MI-1
Length = 273
Score = 99 bits (238), Expect = 1e-19
Identities = 65/189 (34%), Positives = 96/189 (50%), Gaps = 9/189 (4%)
Query: 105 ISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVII 164
I AAA I+CL E + E + W + EPV GP+T ++LA + + II
Sbjct: 30 IRQAAAMGAQIICLPELCTTGYRPDLLEDKLW-ELTEPV-PGPTTDVFSQLAKELGIYII 87
Query: 165 SPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFET 224
P+ E+ + G I N+AV I++ G+V G RK H + YYF +PVF+T
Sbjct: 88 LPMNEKGAVPG-MIHNSAVFIDKDGEVQGVFRKAHA-----YATERYYFTDGNHYPVFQT 141
Query: 225 KYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYT 284
++GKV + ICY P + + GAE++F PSA E +W + A+ N +
Sbjct: 142 EFGKVGVMICYDMGFPEVARILTLKGAEVIFAPSAWRQE-DEDIWDINIAARALENRLFV 200
Query: 285 CAINRVGTE 293
A+NRVG E
Sbjct: 201 AAVNRVGRE 209
>UniRef50_Q972X1 Cluster: 264aa long hypothetical
beta-ureidopropionase; n=1; Sulfolobus tokodaii|Rep:
264aa long hypothetical beta-ureidopropionase -
Sulfolobus tokodaii
Length = 264
Score = 99 bits (238), Expect = 1e-19
Identities = 63/200 (31%), Positives = 108/200 (54%), Gaps = 10/200 (5%)
Query: 99 EKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVK 158
E+ ++++ A + I+ L E N + F + + +AE G + E++ +
Sbjct: 19 ERQVELVNKAIDNKAKIIALDELSNTIY-FPFEQNPKYFSWAETE-RGETLQRFKEISKE 76
Query: 159 YDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTG 218
++ +I PI ERD + +NTA +++ G++IGK+RK H+P+ FNE Y+ G+ G
Sbjct: 77 REVSLIVPIFERDS---NFFYNTAFILDN-GEIIGKYRKTHLPQEEFFNEYYYFKVGDLG 132
Query: 219 HPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAI 278
P+F+ K K + IC+ RH P + I GA ++F PS V+ E +W +E + A+
Sbjct: 133 FPIFDLKGVKTGVVICHDRHFPEPVRVEVIKGAWLIFIPS--VAAFKE-IWELELKAHAV 189
Query: 279 ANSYYTCAINRVGTESFPNE 298
N+ Y INR G E +PN+
Sbjct: 190 FNTVYIAGINRFGKE-YPNQ 208
>UniRef50_Q606Z9 Cluster: Hydrolase, carbon-nitrogen family; n=38;
Bacteria|Rep: Hydrolase, carbon-nitrogen family -
Methylococcus capsulatus
Length = 295
Score = 94.7 bits (225), Expect = 4e-18
Identities = 73/271 (26%), Positives = 122/271 (45%), Gaps = 22/271 (8%)
Query: 105 ISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVII 164
I + A+ +++ L E P+ FC E D AE + GP+T L +A + +V++
Sbjct: 29 IRRSKAKGADLVMLPELHLGPY-FCQTEDCSCFDGAETI-PGPTTAELGSVARELGVVVV 86
Query: 165 SPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFET 224
+ + ER NTAVV++ G + GK+RK HIP + E Y+ G+ G +T
Sbjct: 87 ASLFERRA--PGLYHNTAVVLDSDGSLAGKYRKMHIPDDPGYYEKFYFTPGDLGFRPIDT 144
Query: 225 KYGKVAINICYGRHHPLNWLMFGINGAEIV-------FNPSATVSGLSEHL--WAVEARN 275
G++ + +C+ + +P + + GA+++ +NP+ S L W R
Sbjct: 145 SVGRLGVLVCWDQWYPEAARLMALAGADLLLYPTAIGWNPADDEVERSRQLEAWITVQRG 204
Query: 276 AAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIK 335
A+AN A NR+G+E P+ T G F+G+S+ P G
Sbjct: 205 HAVANGLTVAACNRIGSEPDPSGQTPGI---------LFWGNSFAAGPQGEFLCRAGSAD 255
Query: 336 DGLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
LL+ VD ++ W F +R+D Y
Sbjct: 256 TELLMVTVDRKRSEDVRRIWPFLRDRRIDGY 286
>UniRef50_Q6AHZ8 Cluster: Putative uncharacterized protein
DKFZp779O1248; n=1; Homo sapiens|Rep: Putative
uncharacterized protein DKFZp779O1248 - Homo sapiens
(Human)
Length = 186
Score = 90.2 bits (214), Expect = 8e-17
Identities = 52/149 (34%), Positives = 84/149 (56%), Gaps = 5/149 (3%)
Query: 1 MASAELTSLDEVISNSLKGKELEEFNRIHYGRIDQCALFISSVAAQKAASNGFEIKAYDF 60
MA AE SL+E + L +L+E R+ YG+ + L + A + A+ FE++ Y F
Sbjct: 1 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGK-ELRKLDLPREAFEAASREDFELQGYAF 59
Query: 61 PARKEECRKPRIVRLGLIQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQE 120
A +E+ R+PRIV +GL+Q+ I + + P+ +Q A+ +++ I+ AA VNI+C QE
Sbjct: 60 EAAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQE 119
Query: 121 AWNM-PFAFCTREKQPWCDFAEPVLTGPS 148
AW + P +E +P C +A PS
Sbjct: 120 AWILRPH---HQEPRPPCCYAPSCCLIPS 145
>UniRef50_Q89413 Cluster: A78R protein; n=6; Chlorovirus|Rep: A78R
protein - Paramecium bursaria Chlorella virus 1 (PBCV-1)
Length = 298
Score = 89.8 bits (213), Expect = 1e-16
Identities = 57/203 (28%), Positives = 94/203 (46%), Gaps = 10/203 (4%)
Query: 99 EKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVK 158
E+ + ++ AAA ++ LQE + + FC + + FA+P ++LA +
Sbjct: 23 ERAEMLVRNAAANGAQVIVLQELFATKY-FCQTQSPQYFKFADPADDSVIVEIFSKLAKE 81
Query: 159 YDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTG 218
+VI P E+D G+ +N+ V + G ++G +RK HIP+ + E Y+ +
Sbjct: 82 LGVVIPIPFFEKD---GNNYYNSVAVADADGSIVGVYRKTHIPQSKCYEEKFYFTPSSNP 138
Query: 219 HPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVS------GLSEHLWAVE 272
+ VFETK+GK+ + IC+ + + GA+ + P+A S G S WA
Sbjct: 139 YEVFETKFGKMGVLICWDQWFSEAAKCLALEGADFIVYPTAIGSEPEFPNGESYLHWART 198
Query: 273 ARNAAIANSYYTCAINRVGTESF 295
A A NRVG E F
Sbjct: 199 ITGHAAATGVPVIVANRVGRERF 221
>UniRef50_A6QC56 Cluster: Hydrolase; n=2; Bacteria|Rep: Hydrolase -
Sulfurovum sp. (strain NBC37-1)
Length = 290
Score = 89.8 bits (213), Expect = 1e-16
Identities = 71/271 (26%), Positives = 119/271 (43%), Gaps = 23/271 (8%)
Query: 105 ISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVII 164
I AA+ ++ LQE + FC E + D+A S F +A K+ +V++
Sbjct: 25 IEEAASNSTELIVLQELHQNEY-FCQSEDTAFFDYAADFDADVS--FWGAVAKKHGIVLV 81
Query: 165 SPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFET 224
+ + E+ NTAVV + G + GK+RK HIP F E Y+ G+ G ET
Sbjct: 82 TSLFEKRA--PGLYHNTAVVFEKDGNIAGKYRKMHIPDDPGFYEKFYFTPGDLGFEPIET 139
Query: 225 KYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSA-------TVSGLSEHL--WAVEARN 275
GK+ + +C+ + +P + + GA+++ P+A T + L W R+
Sbjct: 140 SVGKLGVLVCWDQWYPEAARIMALKGAQLLIYPTAIGWFDEDTDKEKARQLDSWITIQRS 199
Query: 276 AAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIK 335
AIAN + NRVG E DG F+G+S++ G
Sbjct: 200 HAIANGIPVLSCNRVGFEP--------DGSGVLNGI-RFWGNSFICGAQGEILAQADGEN 250
Query: 336 DGLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
+ +L A + ++++D W F +R++ Y
Sbjct: 251 EQILYAGIVHERTKEVRDIWPFLRDRRIEAY 281
>UniRef50_A6DDT2 Cluster: HYDROLASE-Predicted amidohydrolase; n=1;
Caminibacter mediatlanticus TB-2|Rep:
HYDROLASE-Predicted amidohydrolase - Caminibacter
mediatlanticus TB-2
Length = 299
Score = 89.8 bits (213), Expect = 1e-16
Identities = 71/273 (26%), Positives = 126/273 (46%), Gaps = 38/273 (13%)
Query: 115 ILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIH 174
++ LQE + FC E + D+AE F ++ ++V+++ + E+ +
Sbjct: 32 LVILQELHQNEY-FCKCENTKYFDYAESF--NEDVEFWRRVSEDKNIVLVTSLFEK--VM 86
Query: 175 GDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINIC 234
+NTAVV ++ GK+ GK+RK HIP F E Y+ G+ P+ +T G++ + +C
Sbjct: 87 DGIYYNTAVVFDK-GKIAGKYRKTHIPDDPGFYEKFYFIPGDEIEPI-DTSIGRLGVLVC 144
Query: 235 YGRHHPLNWLMFGINGAEIVFNPSA---------TVSGLSE------------HLWAVEA 273
+ + +P + + GAEI+ P+A V L E + W
Sbjct: 145 WDQWYPEPARIMALKGAEILIYPTAIGWLMCPEDRVDELCEKENTIEEKEKMLNAWMSVQ 204
Query: 274 RNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSR 333
R A+AN Y A+NRVG E + G F+G S++ P G ++
Sbjct: 205 RGHAVANGVYVIAVNRVGKEKDESGVLGGI---------EFWGRSFIYGPQG-EVIKVAS 254
Query: 334 IKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
K+ ++ A +DL ++++ W F +R++LY
Sbjct: 255 DKEEIIEADIDLGSAKEVRKIWPFFRDRRIELY 287
>UniRef50_Q7M8G2 Cluster: HYDROLASE-Predicted amidohydrolase; n=5;
Bacteria|Rep: HYDROLASE-Predicted amidohydrolase -
Wolinella succinogenes
Length = 290
Score = 85.4 bits (202), Expect = 2e-15
Identities = 67/282 (23%), Positives = 118/282 (41%), Gaps = 23/282 (8%)
Query: 94 RLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLA 153
R A ++ +++I A+ ++ +QE + FC E+ + D+A +
Sbjct: 14 REATIQRSRELILEASKGGAELVVMQELHTSEY-FCQSEETRFFDYAS--FYEEDVRIFS 70
Query: 154 ELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYF 213
+A + +V++ ER NTAVV + G + G++RK HIP F E Y+
Sbjct: 71 SIAKEGGVVLVGSFFERRS--AGIYHNTAVVFEKDGSIAGRYRKMHIPDDPGFYEKFYFT 128
Query: 214 EGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSA----TVSGLSE--- 266
G+ G GK+ + +C+ + +P + + GA+I+ P+A L E
Sbjct: 129 PGDLGFEPISCSLGKLGVLVCWDQWYPEAARLMALKGADILLYPTAIGWFDADDLDEKER 188
Query: 267 --HLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPD 324
W R A+AN A+NRVG E + G F+G S+ P
Sbjct: 189 QKEAWIAIQRGHAVANGLPVVAVNRVGFEKDSSGVLEGI---------RFWGHSFAFGPQ 239
Query: 325 GSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
G S + ++ VD+ +++ W F +R++ Y
Sbjct: 240 GEPLALGSMESEEVIWVDVDMKRSEEVRRIWPFLRDRRIECY 281
>UniRef50_A5C5V4 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 317
Score = 84.6 bits (200), Expect = 4e-15
Identities = 77/293 (26%), Positives = 135/293 (46%), Gaps = 42/293 (14%)
Query: 102 QKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDM 161
++++ A + NI+ +QE + + FC +++ + A+P P+ + + +LA + +
Sbjct: 28 ERLVRDAHRKGANIILIQELFE-GYYFCQAQREDFFQRAKPYKGHPTILRMQKLAKELGV 86
Query: 162 VI-ISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHP 220
VI +S E ++ H +N+ +++ G +G +RK+HIP + E Y+ G+TG
Sbjct: 87 VIPVSFFEEANNAH----YNSIAIVDADGTDLGIYRKSHIPDGPGYQEKFYFNPGDTGFK 142
Query: 221 VFETKYGKVAINICYGRHHPLNWLM--------FGIN------------GAEIVFNPSAT 260
VFETK+ K+ + + N LM GI+ GAEI+ P+A
Sbjct: 143 VFETKFAKIGVGLIVILFRQTNRLMGCIQRVQYAGISGFQRQLELWFFQGAEILLYPTAI 202
Query: 261 VS-----GLS--EHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGH 313
S GL +H W + A AN A NR+G E E + +
Sbjct: 203 GSEPQDTGLDSCDH-WKRVMQGHAGANLVPLVASNRIGKEIIQTEHGNTEIT-------- 253
Query: 314 FYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
FYG+S++ P G ++ +++AQ DL+ + + WG +R DLY
Sbjct: 254 FYGNSFIAGPTGEIVAAADDKEEAVVVAQFDLDKIKSKRYSWGIFRDRRPDLY 306
>UniRef50_Q9UYV8 Cluster: Beta ureidopropionase; n=4;
Thermococcaceae|Rep: Beta ureidopropionase - Pyrococcus
abyssi
Length = 262
Score = 83.8 bits (198), Expect = 7e-15
Identities = 56/197 (28%), Positives = 101/197 (51%), Gaps = 16/197 (8%)
Query: 98 FEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAV 157
+ K +K+I A+ + ++ L E ++ + F TRE+ + A+ + G +T FL ++A
Sbjct: 20 YSKAEKLIKEASKQGAQLVVLPELFDTGYNFETREEV--FEIAQKIPEGETTTFLMDVAR 77
Query: 158 KYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFE-GN 216
+ I++ E+D GD ++N+AVV+ G IGK+RK H+ F ++FE G+
Sbjct: 78 DTGVYIVAGTAEKD---GDVLYNSAVVVGPRG-FIGKYRKIHL-----FYREKFFFEPGD 128
Query: 217 TGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNA 276
G VF+ + KV + IC+ P + + GA+++ +P+ V + +
Sbjct: 129 LGFRVFDLGFMKVGVMICFDWFFPESARTLALKGADVIAHPANLVMPYAPRAMPIR---- 184
Query: 277 AIANSYYTCAINRVGTE 293
A+ N YT +RVG E
Sbjct: 185 ALENKVYTVTADRVGEE 201
>UniRef50_A7I2D9 Cluster: Hydrolase, carbon-nitrogen family; n=1;
Campylobacter hominis ATCC BAA-381|Rep: Hydrolase,
carbon-nitrogen family - Campylobacter hominis (strain
ATCC BAA-381 / LMG 19568 / NCTC 13146 /CH001A)
Length = 336
Score = 83.4 bits (197), Expect = 9e-15
Identities = 58/205 (28%), Positives = 96/205 (46%), Gaps = 14/205 (6%)
Query: 99 EKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVK 158
+K ++I A + ++ LQE + FC E+ +FA S F E A K
Sbjct: 22 QKSVEMIEKVAKDGAKLVILQELHEWAY-FCQSERVE--NFALAENFNESLKFWGETAKK 78
Query: 159 YDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTG 218
+ +V+++ + E+ NTA+V G++ GK+RK HIP +F E Y+ G+ G
Sbjct: 79 FGIVLVTSLFEKRA--PGLFHNTAIVFENNGEIAGKYRKMHIPDDPNFYEKFYFTPGDLG 136
Query: 219 HPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSAT--VSGLSE-------HLW 269
T G++ + +C+ + +P + + GAEI+ P+A G E W
Sbjct: 137 FEPINTSVGRLGVLVCWDQWYPEAARLMALKGAEILIYPTAIGWFDGDDEAEKSRQLEAW 196
Query: 270 AVEARNAAIANSYYTCAINRVGTES 294
R A+AN+ A+NRVG E+
Sbjct: 197 VAVQRGHAVANALPVIAVNRVGFEA 221
>UniRef50_A6CCK5 Cluster: Putative uncharacterized protein; n=1;
Planctomyces maris DSM 8797|Rep: Putative
uncharacterized protein - Planctomyces maris DSM 8797
Length = 450
Score = 82.6 bits (195), Expect = 2e-14
Identities = 76/256 (29%), Positives = 122/256 (47%), Gaps = 26/256 (10%)
Query: 59 DFPARKEECRKPRIVRLGLIQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCL 118
D ++ + +PRIVRL I H + A K+I AA ++ +++ L
Sbjct: 183 DINLKQTKDLQPRIVRLATIHHRPQAGKKPSDKPAQFA------KLIEQAAEQKADLVVL 236
Query: 119 QEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTI 178
E+ + + + + AEP+ GPST + ELA K+D+ I+ + ER +
Sbjct: 237 PESITVYGTGLS-----YAETAEPI-PGPSTQYFGELAKKHDLYIVVGLYERA---AHLV 287
Query: 179 WNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRH 238
+N AV+I GKV+GK+RK +PR G+ GN +PVFET++GKV + +CY
Sbjct: 288 YNVAVLIGPDGKVVGKYRKVTLPR-GEIEGGV--TPGNE-YPVFETRFGKVGMMVCYDGF 343
Query: 239 HPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNE 298
P NGAE++ P + L A E I+++Y + N + + + +
Sbjct: 344 FPEVARELSKNGAEVIAWPVWGCNPLLGAARACENHVYVISSTYTDTSSNWMISAIYGH- 402
Query: 299 FTSGDGKP--AHKDFG 312
DGKP KD+G
Sbjct: 403 ----DGKPLAQAKDWG 414
>UniRef50_Q2AH52 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Halothermothrix
orenii H 168|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Halothermothrix
orenii H 168
Length = 273
Score = 80.2 bits (189), Expect = 8e-14
Identities = 64/223 (28%), Positives = 97/223 (43%), Gaps = 23/223 (10%)
Query: 144 LTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRV 203
+ G +T +E A Y II ++ERD G+ ++NT VI++ G GK+RK H+
Sbjct: 65 IPGRTTEIFSEYARMYKTAIIGNMVERDKNVGEILYNTTFVIDKKGDYTGKYRKVHV--- 121
Query: 204 GDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSG 263
+ YF+ T PVF K+ + CY + + GA+I+F PSA G
Sbjct: 122 --YPAEFTYFKRGTEFPVFNVNGVKIGLATCYDHGFGEMFRILARKGAQIIFIPSAIPKG 179
Query: 264 LSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAP 323
E+L + R A N +T A+N G PN HF G+S V P
Sbjct: 180 Y-EYLLKLRTRARAQDNQLFTVAVNSAG--KTPN--------------SHFCGNSMVVNP 222
Query: 324 DGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
G +G+ +A++DL L + + + DLY
Sbjct: 223 RGEIIQEADD-GEGVFLAELDLELIERERKQEPLIRDSAFDLY 264
>UniRef50_O59829 Cluster: Nitrilase; n=2; cellular organisms|Rep:
Nitrilase - Schizosaccharomyces pombe (Fission yeast)
Length = 272
Score = 79.8 bits (188), Expect = 1e-13
Identities = 64/233 (27%), Positives = 110/233 (47%), Gaps = 23/233 (9%)
Query: 140 AEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH 199
AE GPS ++ LA KY + II E+++ + I+N+ + I E G + G +RK H
Sbjct: 61 AEIAGEGPSFKTMSNLAAKYHVNIIYGFPEKEEKQSNIIYNSCIYITENGNLGGVYRKVH 120
Query: 200 IPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSA 259
+ F+ +F+ + P+FET +GK+ + IC+ P + +NGA+++ +
Sbjct: 121 L-----FDTERKHFKKGSDFPIFETSFGKLGVMICWDTAFPEVARIHALNGADLLVVATN 175
Query: 260 TVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSY 319
+ S+ W + + A N A NRVGT+ E S F+G S
Sbjct: 176 WENPYSDD-WDLVTKARAFENCIPLVAANRVGTD----EKLS------------FFGHSK 218
Query: 320 VTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQI-KDKWGFTMTQRLDLYAQSLN 371
+ P G L K+G++ VDL+ + + K+ + F + DLY + L+
Sbjct: 219 IIGPTGKVIKALDEEKEGVISYTVDLDDAKPLRKNYYTFFEDRMPDLYKRLLS 271
>UniRef50_A6TPX2 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Alkaliphilus
metalliredigens QYMF|Rep: Nitrilase/cyanide hydratase
and apolipoprotein N-acyltransferase - Alkaliphilus
metalliredigens QYMF
Length = 269
Score = 79.0 bits (186), Expect = 2e-13
Identities = 58/206 (28%), Positives = 96/206 (46%), Gaps = 11/206 (5%)
Query: 89 PITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPS 148
PI A ++ Q I AAA++V+++ L E W + K+ + AE G +
Sbjct: 11 PIMNDVEANLKRGQHFIQQAAAQEVDLIVLPELWTTGYYL---SKESFKQLAEHK-DGRT 66
Query: 149 TVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNE 208
+ + A++ + II P +E + ++ A VI+ G++ G K+ + E
Sbjct: 67 VTLMQDQALRSNASIICPFVEITE--DKKLYIAAAVIDHRGELRGTVHKSLLWG----RE 120
Query: 209 STYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHL 268
+ EGN +PVF+TK GKV I ICY P + + G E++ PS S + H
Sbjct: 121 QQIFEEGNIEYPVFDTKIGKVGILICYEMEFPETSRLLALQGVEMIVCPSVW-SLSASHR 179
Query: 269 WAVEARNAAIANSYYTCAINRVGTES 294
W ++ A+ N+ Y +N VG S
Sbjct: 180 WDIQLPARALDNTVYVFGVNTVGNNS 205
>UniRef50_Q0LQX0 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Nitrilase/cyanide hydratase
and apolipoprotein N-acyltransferase - Herpetosiphon
aurantiacus ATCC 23779
Length = 259
Score = 77.8 bits (183), Expect = 4e-13
Identities = 60/222 (27%), Positives = 104/222 (46%), Gaps = 14/222 (6%)
Query: 78 IQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWC 137
+Q ++A++ + + R A V+++ + A +L L E W + +
Sbjct: 1 MQLTVALAQIDLVLGDREANLATVRQLAARAEMAGAALLVLPELWGTGYLL-----EQAH 55
Query: 138 DFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRK 197
+ ++P+ G +A LA ++ + I+ +LERD G+ ++NTA + + GK + +RK
Sbjct: 56 ELSDPLGKGLFEE-VAVLAARHHLAIVGSLLERD---GEQVYNTATLYDAQGKRLHSYRK 111
Query: 198 NHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNP 257
H+ +G E Y G VFET +G A ICY P + + + GA ++ P
Sbjct: 112 THL--IGLMQEDRYLAAGQQAE-VFETAWGTSACAICYDLRFPELFRRYALAGAGVIIIP 168
Query: 258 SATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEF 299
+ + EH W R AI N A NRVG++ N+F
Sbjct: 169 AEWPTARIEH-WRTLLRARAIENQAVVIACNRVGSDR-ANQF 208
>UniRef50_A0QWL8 Cluster: Carbon-nitrogen hydrolase family protein;
n=6; Bacteria|Rep: Carbon-nitrogen hydrolase family
protein - Mycobacterium smegmatis (strain ATCC 700084 /
mc(2)155)
Length = 299
Score = 77.8 bits (183), Expect = 4e-13
Identities = 60/228 (26%), Positives = 111/228 (48%), Gaps = 24/228 (10%)
Query: 74 RLGLIQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREK 133
R+ ++Q + + +N + A++E++Q+ ++ A N++ L E + F +RE+
Sbjct: 13 RVAVVQFNPQVGVEN-LKANSEAVYERLQQAVAGGA----NLIVLPELATTGYTFESREE 67
Query: 134 QPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIG 193
AEPV +G + AE A +D+ I+ + E D + +++TAV++ G IG
Sbjct: 68 A--YAHAEPVPSGATVTGWAEFAAAHDVYIVGCLPELDGVE---LFDTAVLVGPEG-YIG 121
Query: 194 KHRKNHIPRVGDFNESTYYFE-GNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAE 252
K+RK H+ +NE +F G+ G+PVF T+ G++ + +C+ P + GA+
Sbjct: 122 KYRKTHL-----WNEEKLFFSPGDLGYPVFHTRIGRIGLLVCWDIWFPETARIVAQQGAD 176
Query: 253 I-------VFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTE 293
I V+ P + A AA N+ + +R+GTE
Sbjct: 177 IICIPTGWVWTPPPLYDDSGTCMAAYLTMTAAHVNNVFIATADRIGTE 224
>UniRef50_A7GE66 Cluster: Hydrolase, carbon-nitrogen family; n=13;
cellular organisms|Rep: Hydrolase, carbon-nitrogen
family - Clostridium botulinum (strain Langeland / NCTC
10281 / Type F)
Length = 278
Score = 77.4 bits (182), Expect = 6e-13
Identities = 66/283 (23%), Positives = 129/283 (45%), Gaps = 26/283 (9%)
Query: 90 ITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPST 149
+ +++ +K ++++ A E NI L E +N P+ + +P+ + G +
Sbjct: 13 VQKEKKKNIKKAIEMLTKAKKENCNIAVLPEMFNCPYE--NKCFKPYGEIINEENGGETV 70
Query: 150 VFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVG----- 204
+ + A ++ I++ + +I GD I+NT++V + G +I KHRK H+ +
Sbjct: 71 KAIKKAAKDLELYIVAGSIP--EIEGDKIYNTSMVFDNKGVLIAKHRKVHLFDIDVKGGV 128
Query: 205 DFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGL 264
F ES GN +F T +GK+ + ICY P + + GA+I+F P+A
Sbjct: 129 TFKESDTLTAGNK-ITLFNTPWGKLGVMICYDIRFPELSRIMAVKGAKIIFTPAAFNMTT 187
Query: 265 SEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPD 324
W ++ A+ N Y + E+ + + S YG+S + +P
Sbjct: 188 GPAHWDTLFKSRALDNQVYMVGVAPARDEN--SNYVS-------------YGNSLIASPW 232
Query: 325 GSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLYA 367
G+ L K+ +L +++DL+ +I+++ R D+Y+
Sbjct: 233 GNILAKLD-AKEDILFSEIDLDYESKIREELPLLKHIRKDIYS 274
>UniRef50_Q0AX54 Cluster: N-carbamoyl-D-amino acid amidohydrolase;
n=1; Syntrophomonas wolfei subsp. wolfei str.
Goettingen|Rep: N-carbamoyl-D-amino acid amidohydrolase
- Syntrophomonas wolfei subsp. wolfei (strain
Goettingen)
Length = 283
Score = 72.5 bits (170), Expect = 2e-11
Identities = 60/194 (30%), Positives = 93/194 (47%), Gaps = 15/194 (7%)
Query: 99 EKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVK 158
+K ++I+AAA E ++ L E +N P+ + + + +AEP GPST FLA A K
Sbjct: 23 KKAGEMIAAAAGEGAEMVVLPEVFNSPY-----QAELFPRYAEP-FPGPSTDFLAAAACK 76
Query: 159 YDMVIIS-PILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH-----IPRVGDFNESTYY 212
+ + I+ I+ERD I+N++ V +E G++IG+HRK H IP F ES
Sbjct: 77 HGLCIVGGSIIERDS--QGKIYNSSFVFDERGELIGRHRKAHLFDIDIPGRISFRESDTL 134
Query: 213 FEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVE 272
G + K A+ ICY P + GAE++ P+A + W +
Sbjct: 135 NAGE-NITIVHYKSRLFALMICYDCRFPELARAAALEGAELLVIPAAFNTTTGPAHWKLL 193
Query: 273 ARNAAIANSYYTCA 286
R A+ N + A
Sbjct: 194 MRCRAVDNQLFVVA 207
>UniRef50_Q44185 Cluster: N-carbamoyl-D-amino acid hydrolase; n=10;
Proteobacteria|Rep: N-carbamoyl-D-amino acid hydrolase -
Agrobacterium tumefaciens
Length = 304
Score = 72.1 bits (169), Expect = 2e-11
Identities = 48/184 (26%), Positives = 92/184 (50%), Gaps = 17/184 (9%)
Query: 179 WNTAVVINEFGKVIGKHRKNHIPRVGDFN--------ESTYYFEGNTGHPVFETKYGKVA 230
+NT++++++ GK++GK+RK H+P ++ E Y+ G+ G PV++ K+
Sbjct: 109 FNTSILVDKSGKIVGKYRKIHLPGHKEYEAYRPFQHLEKRYFEPGDLGFPVYDVDAAKMG 168
Query: 231 INICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRV 290
+ IC R P W + G+ GAEI+ T + H V + S++ +
Sbjct: 169 MFICNDRRWPETWRVMGLKGAEIICGGYNTPT----HNPPVPQHDH--LTSFHHLLSMQA 222
Query: 291 GTESFPN-EFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCR 349
G S+ N +++ GK ++ G S + AP G + ++D ++ A VDL+ CR
Sbjct: 223 G--SYQNGAWSAAAGKVGMEEGCMLLGHSCIVAPTGEIVALTTTLEDEVITAAVDLDRCR 280
Query: 350 QIKD 353
++++
Sbjct: 281 ELRE 284
>UniRef50_Q183H2 Cluster: Putative carbon-nitrogen hydrolase; n=2;
Clostridium difficile|Rep: Putative carbon-nitrogen
hydrolase - Clostridium difficile (strain 630)
Length = 268
Score = 71.7 bits (168), Expect = 3e-11
Identities = 42/145 (28%), Positives = 76/145 (52%), Gaps = 11/145 (7%)
Query: 152 LAELAVKYDMVIISPI--LERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNES 209
++E A + ++ +ISP LE+ H ++N+AV+ + GK++G++ KNH+ ++
Sbjct: 76 MSEAAKRNNVYLISPYGTLEKGSTH---VYNSAVIFDRKGKIMGEYCKNHL-----WSLE 127
Query: 210 TYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLW 269
YF+G V++ +G+ + ICY P + G+EI+F PSA E +W
Sbjct: 128 AVYFKGGEKVEVYDADFGRFGVMICYDAGFPEVSRELTLKGSEIIFIPSAW-RIQDEDMW 186
Query: 270 AVEARNAAIANSYYTCAINRVGTES 294
+ A+ N+ YT +N V +S
Sbjct: 187 DLNVSQRALENTVYTVGVNLVSNDS 211
>UniRef50_Q4P4D1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 373
Score = 71.7 bits (168), Expect = 3e-11
Identities = 63/228 (27%), Positives = 99/228 (43%), Gaps = 11/228 (4%)
Query: 147 PSTVFLAELAVKYDMVIIS-PILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH-----I 200
PS L+E A + ++V++ + ERDD+ G+ I+N++ V NE G++I HRK H I
Sbjct: 143 PSLKMLSETAREANVVLVGGSVPERDDLTGN-IYNSSCVFNEKGQLISIHRKLHLFDIDI 201
Query: 201 PRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSAT 260
P F ES G +F+ G+ + ICY P ++ G GA + P A
Sbjct: 202 PGKMTFQESE-TLAGGDRVTLFDCSLGRFGLGICYDLRFPEPAMIAGRLGAGCIIYPGAF 260
Query: 261 VSGLSEHLWAVEARNAAIANSYYT--CAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSS 318
+ W + R A N YT C+ R ++ E T DG + +G S
Sbjct: 261 NTTTGPVSWELLLRARATDNQVYTLGCSPARPSQQALDGELTDKDGWREGEKAYPAWGHS 320
Query: 319 YVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
V P G L+ + L +D +Q + + +R D+Y
Sbjct: 321 SVVGPLGDVKAKLAE-AEATLFFTLDPEEVQQTRKNIPISTQRRFDVY 367
>UniRef50_Q6N746 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=11;
Proteobacteria|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Rhodopseudomonas
palustris
Length = 579
Score = 71.3 bits (167), Expect = 4e-11
Identities = 74/245 (30%), Positives = 114/245 (46%), Gaps = 31/245 (12%)
Query: 128 FCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINE 187
+C ++ F EP+ G +T AELA K+D I+ + E D+ +N+AV+I
Sbjct: 51 YCWYDRAEVAPFVEPI-PGATTARFAELARKHDCYIVVGLPEVDE--DGIYYNSAVLIGP 107
Query: 188 FGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFG 247
G +IG+HRK H P + +E + G+ + VF+T G++A+ IC H +
Sbjct: 108 EG-LIGRHRKTH-PYI---SEPKWSAAGDLHNQVFDTPIGRIALLICMDIHFVETARLMA 162
Query: 248 INGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPA 307
+ GA+I+ + S + L+E A + A NS Y NR G E
Sbjct: 163 LGGADIICHIS---NWLAERTPAPYWISRAFENSCYVIESNRWGLERTV----------- 208
Query: 308 HKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNL--CRQIKDKWGFTMTQRLDL 365
F G S V APDGS + DG+ A++DL+ RQI + F +R +L
Sbjct: 209 -----QFSGGSCVIAPDGSIAAVIDG-GDGVAFAEIDLDTARARQIGGEAVFRQ-RRPEL 261
Query: 366 YAQSL 370
Y + L
Sbjct: 262 YPELL 266
Score = 42.7 bits (96), Expect = 0.016
Identities = 34/114 (29%), Positives = 58/114 (50%), Gaps = 9/114 (7%)
Query: 146 GPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGD 205
GP+T LA LA + + ++ + ERD GD ++N+AV+I G I +RK H+
Sbjct: 349 GPATDRLAALASELSLYLVCGLAERD---GDILYNSAVLIAPDG-TITTYRKTHLTE--- 401
Query: 206 FNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSA 259
NE + G++ V +T G+V + I + P + + G +I+ P+A
Sbjct: 402 -NERGWAQPGDS-FVVCDTPLGRVGLLIGHDAIFPEAGRVLALRGCDIIACPAA 453
>UniRef50_A4J6K3 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Desulfotomaculum
reducens MI-1|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Desulfotomaculum
reducens MI-1
Length = 277
Score = 71.3 bits (167), Expect = 4e-11
Identities = 61/204 (29%), Positives = 93/204 (45%), Gaps = 16/204 (7%)
Query: 101 VQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYD 160
++K I+ AAA+Q I+C E M +RE DF + G + +FL +LA
Sbjct: 25 LEKFINEAAAQQAEIICFPE---MCIQGYSREIP---DFLLQSIDGEAILFLKKLAQNKG 78
Query: 161 MVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHP 220
+ II+ + E+ + T VVI G+ I +RK H+ +E YY GN
Sbjct: 79 ITIIAGMAEK--CLNKRPFITQVVIRP-GQNIDYYRKTHLGN----SEQPYYQAGNE-IK 130
Query: 221 VFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNP--SATVSGLSEHLWAVEARNAAI 278
F T+ + I IC+ H P + + GAE++F P S T+ G + +W A
Sbjct: 131 TFSTEKTTIGIQICWDTHFPEMTTILSLRGAEVIFAPHASPTIVGDRKAIWLKYLAARAY 190
Query: 279 ANSYYTCAINRVGTESFPNEFTSG 302
NS + A N VG + +F G
Sbjct: 191 DNSVFLAACNLVGDDGNGRQFCGG 214
>UniRef50_A4M5M1 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Petrotoga mobilis
SJ95|Rep: Nitrilase/cyanide hydratase and apolipoprotein
N-acyltransferase - Petrotoga mobilis SJ95
Length = 276
Score = 70.5 bits (165), Expect = 7e-11
Identities = 44/157 (28%), Positives = 79/157 (50%), Gaps = 6/157 (3%)
Query: 138 DFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRK 197
+ AE + G +T + +A KY++ I++ ILE+D + ++T+++I+E GK++GK+RK
Sbjct: 59 NLAEIIPDGETTQEVVRIAKKYNISIVANILEKDPLIIGKYYDTSILIDESGKLLGKYRK 118
Query: 198 NHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNP 257
+ F + + T + + K K+ ++ICY P + + + GA+I+
Sbjct: 119 IFV-----FPKEKFRLSEGTSIEIIDWKGIKIGLSICYDHAFPELYRIMALRGAQILIIT 173
Query: 258 SATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTES 294
SA G E L V A N + +N VG S
Sbjct: 174 SAVPKGF-EKLVEVRTSARAQDNQLFAIGVNAVGKPS 209
>UniRef50_A1HQ26 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Thermosinus
carboxydivorans Nor1|Rep: Nitrilase/cyanide hydratase
and apolipoprotein N-acyltransferase - Thermosinus
carboxydivorans Nor1
Length = 258
Score = 69.7 bits (163), Expect = 1e-10
Identities = 65/262 (24%), Positives = 111/262 (42%), Gaps = 29/262 (11%)
Query: 105 ISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVII 164
++ A + +++ L E W +A RE W + E G + ++ ++ KY II
Sbjct: 25 LAQEGAARADVVVLPEIWTTGYAL--REVDKWAEDVE----GLTISEMSNISRKYGAYII 78
Query: 165 SPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFET 224
+ + ++N AVVI G V ++RK H+ + E ++ G+ F
Sbjct: 79 AGSIPLRK--NGKVYNGAVVIGPDGNVAAEYRKIHLFSM--MGEERFFAAGDR-RCTFNL 133
Query: 225 KYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYT 284
K I ICY P + + ++GA+IVF P+ + EH W + +R AI N +
Sbjct: 134 KGVTAGIAICYDLRFPELFRVLALDGAQIVFLPAEWPTARGEH-WHLLSRTRAIENQVFL 192
Query: 285 CAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVD 344
C +N VG G P FYG S + P G ++ +L A+ D
Sbjct: 193 CVVNCVGEHK---------GNP-------FYGHSMLIGPSG-EVLAEGGEEETILYAEAD 235
Query: 345 LNLCRQIKDKWGFTMTQRLDLY 366
L + ++K +R ++Y
Sbjct: 236 FALVAKAREKMSVWQDRRPEVY 257
>UniRef50_A0QPL8 Cluster: Hydrolase, carbon-nitrogen family protein;
n=6; Bacteria|Rep: Hydrolase, carbon-nitrogen family
protein - Mycobacterium smegmatis (strain ATCC 700084 /
mc(2)155)
Length = 330
Score = 69.7 bits (163), Expect = 1e-10
Identities = 70/288 (24%), Positives = 123/288 (42%), Gaps = 31/288 (10%)
Query: 105 ISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVII 164
I AA E + L E + + T D AE + GP+ AE A + +
Sbjct: 47 IDRAAGEGAKAVFLPEITLLRYPADTPAGPNPGDVAEDLTGGPTFELAAEAARANGIFVH 106
Query: 165 SPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEG------NTG 218
+ + E+ +NTA++++ G+++G+ RK HIP + E TY+ G
Sbjct: 107 ASLYEKAPAADGLGYNTAILVSPEGELVGRTRKMHIPISAGYYEDTYFRPGPARPSDGDP 166
Query: 219 HPVF--ETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGL------SEHLWA 270
+PV+ E ++ + C+ P + + GAEIV P+A S ++ LW
Sbjct: 167 YPVYSPEGLGARIGLPTCWDEWFPEVARCYSLGGAEIVVYPTAIGSEPVFPAFDTQPLWQ 226
Query: 271 VEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPG 330
I++ + NR G E + FYGSS+++ P G
Sbjct: 227 QVIVANGISSGLFMVVPNRTGDEGSLS----------------FYGSSFISDPFGRVLVS 270
Query: 331 LSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLYAQSLNEAIKHDY 378
R ++ +L+A +DL+ R + + F +T+R + Y +L E + D+
Sbjct: 271 APRDEEAVLVADLDLDQRRDWLELFPFLLTRRPESYG-ALTEPVDPDH 317
>UniRef50_O30121 Cluster: Putative uncharacterized protein; n=1;
Archaeoglobus fulgidus|Rep: Putative uncharacterized
protein - Archaeoglobus fulgidus
Length = 257
Score = 69.7 bits (163), Expect = 1e-10
Identities = 47/139 (33%), Positives = 76/139 (54%), Gaps = 8/139 (5%)
Query: 152 LAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTY 211
L +++ + D++II+ + ER+ GD ++N+AV+I++ GK+IGK+RK H+ + NE Y
Sbjct: 70 LLKISEQKDIMIITGVAERE---GDDLYNSAVIIHK-GKIIGKYRKTHLFPLT--NEKKY 123
Query: 212 YFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAV 271
+ G+ VFET GK+ + ICY P GAEI+ P+ +H W V
Sbjct: 124 FKAGDKLE-VFETHLGKIGLLICYEVRFPELSRKLVKMGAEIIVIPAEFPKERIDH-WRV 181
Query: 272 EARNAAIANSYYTCAINRV 290
+ AI N + +N V
Sbjct: 182 LLQARAIENQVFVAGVNCV 200
>UniRef50_A0JSY8 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=4;
Actinomycetales|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Arthrobacter sp.
(strain FB24)
Length = 344
Score = 69.3 bits (162), Expect = 2e-10
Identities = 65/256 (25%), Positives = 114/256 (44%), Gaps = 33/256 (12%)
Query: 138 DFAEPVLTGPSTVFLAELAVKYDMVIISPILER---DDIHGDTIW-NTAVVINEFGKVIG 193
D AE +LTGP+ F A A ++ + + + + +R D D + NT+V+++ G+++
Sbjct: 91 DLAEDLLTGPTFRFAAGAARRHGITVHASLYQRAENPDGSDDGLGLNTSVLVSPEGELLA 150
Query: 194 KHRKNHIPRVGDFNESTYYFEGNTGHPVFETKY------GKVAINICYGRHHPLNWLMFG 247
+ K HIP + E ++ G +E ++ + C+ P ++
Sbjct: 151 RTHKLHIPVTAGYYEDKFFRPGPAVEDAYEVHSPAELGGARLGMPTCWDEWFPELARLYS 210
Query: 248 INGAEIVFNPSATVSGL------SEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTS 301
+ GAEI+ P+A S ++ LW IAN + A NR G+E N
Sbjct: 211 LGGAEILVYPTAIGSEPDHPDFDTQPLWQQVIVGNGIANGLFMVAPNRWGSEGTLN---- 266
Query: 302 GDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQ 361
FYGSS+++ P G R + +L+A +DL+ R + F T+
Sbjct: 267 ------------FYGSSFISDPYGRILAQAPRDESAVLVADLDLDQRRDWLTLFPFLATR 314
Query: 362 RLDLYAQSLNEAIKHD 377
R D YA+ L + ++ D
Sbjct: 315 RPDTYAR-LTDPVRRD 329
>UniRef50_A6TL48 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=2;
Clostridiaceae|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Alkaliphilus
metalliredigens QYMF
Length = 296
Score = 68.9 bits (161), Expect = 2e-10
Identities = 44/162 (27%), Positives = 81/162 (50%), Gaps = 5/162 (3%)
Query: 138 DFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRK 197
+ EP+ G T + +LA + ++ P+ ER + ++N++++I++ G++IGK+RK
Sbjct: 62 EILEPI-PGRHTRDIQKLAKELGTHVVFPLYERGKNKRE-VFNSSLMIDDRGEIIGKYRK 119
Query: 198 NHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNP 257
H P + E + V +TK GK+ + ICY P + + GAEI+ P
Sbjct: 120 TH-PFPTERKEGGGWTTPGNETVVVDTKLGKIGMIICYDGDFPELSRVLALKGAEIITRP 178
Query: 258 SATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEF 299
SA + S +W + + A N Y +N +G ++ N +
Sbjct: 179 SALLR--SFEIWEMTNKARAYDNHVYVLGVNAIGPDAAENYY 218
>UniRef50_A0BLB1 Cluster: Chromosome undetermined scaffold_114,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_114,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 284
Score = 68.9 bits (161), Expect = 2e-10
Identities = 70/286 (24%), Positives = 129/286 (45%), Gaps = 32/286 (11%)
Query: 96 AIFEKVQKIISAAAA-------EQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPS 148
A+FE QKI+ AA ++ ++ L E +N F +K DF++ +
Sbjct: 15 AVFETKQKILEGVAASIRDCVQKECKVIFLGEFFNTIFETNQLKKNAE-DFSDKN-NRET 72
Query: 149 TVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNE 208
+ +L+ ++ ++II + E D ++N A+ N+ GK++G++RK H+ V D
Sbjct: 73 YELMKQLSEEFQIMIIGGLPEVAD---GKLFNAALAFND-GKLVGQYRKCHLFDV-DIPG 127
Query: 209 STYYFEGNT-----GHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSG 263
+FE NT + +F+++YG+ + ICY P+ + G +++ PSA
Sbjct: 128 GITHFESNTFGSGNDYCIFDSQYGRYGLGICYDIRFPIYSQVMRDQGCQVLSFPSAFNQT 187
Query: 264 LSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAP 323
W + R+ A+ N Y + + S D D+ +G S +T P
Sbjct: 188 TGPLHWELLNRSRALDNQVYVASAQAA-------RYYSDD-----PDYYQTWGHSIITDP 235
Query: 324 DGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLYAQS 369
G R +LI +++L+L Q++ ++ +R DLY S
Sbjct: 236 MG-RVLATCESDPAVLIQEINLSLVDQVRKNIPTSVQKRTDLYQVS 280
>UniRef50_A6CCB9 Cluster: Predicted amidohydrolase; n=1;
Planctomyces maris DSM 8797|Rep: Predicted
amidohydrolase - Planctomyces maris DSM 8797
Length = 282
Score = 68.5 bits (160), Expect = 3e-10
Identities = 53/197 (26%), Positives = 94/197 (47%), Gaps = 15/197 (7%)
Query: 97 IFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELA 156
I EK+++ +A A+ V C +C + +AE + GPST L E+
Sbjct: 22 IIEKIKETAAAGASLTVFPECALTG------YCFASLEEALPYAESI-PGPSTDRLQEIC 74
Query: 157 VKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGN 216
+ + ++ +LE+ + ++N AV+I G V+G +RK H+P +G +T G+
Sbjct: 75 RELNHSVVVGMLEQAE---QGVYNAAVLITPEG-VLGSYRKIHLPYLGVDRFAT---PGD 127
Query: 217 TGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNA 276
V+ + +NICY P + + I GA+++ P+ +G + H+
Sbjct: 128 RDFAVYSHPEANIGLNICYDSAFPESSRIMTIEGADLIVLPTNWPTG-ANHVAEHAINTR 186
Query: 277 AIANSYYTCAINRVGTE 293
++ N Y CAINR+G E
Sbjct: 187 SMENGIYYCAINRIGAE 203
>UniRef50_Q6RWQ0 Cluster: Nitrilase; n=3; uncultured organism|Rep:
Nitrilase - uncultured organism
Length = 325
Score = 68.1 bits (159), Expect = 4e-10
Identities = 79/289 (27%), Positives = 125/289 (43%), Gaps = 35/289 (12%)
Query: 78 IQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQEA----------WNMPFA 127
I + AI + PI A EK ++I AA N++ EA W A
Sbjct: 7 IVRAAAIQAE-PIVLDCDATVEKACRLIGEAAENGANLIVFPEAFIPVYPNAAIWGRGLA 65
Query: 128 FC--TREKQPWCDF--AEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAV 183
R+K W + GP+T LA+ A + ++ + ER + +T++NT +
Sbjct: 66 TFGGQRQKYVWTRLWNNSVEIPGPATDRLAKAAHEARATVVMGLNERA-VDNNTLYNTLL 124
Query: 184 VINEFGKVIGKHRK----NHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHH 239
I G+++GKHRK NH + +G+T VF+T GKV IC+ +
Sbjct: 125 FIGPDGRLLGKHRKLMPTNHERMIWGMG------DGSTLR-VFDTPCGKVGGLICWENYM 177
Query: 240 PL-NWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRV-GTESFPN 297
PL + ++G G +I P+A + V ARN A + ++ + SFP+
Sbjct: 178 PLARYALYG-QGEQIHVAPTAH----DGEITLVNARNTAYEGRLFVISVCMILRKSSFPH 232
Query: 298 EFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLN 346
+F G+ DF G S + PDG G ++ +L A +DLN
Sbjct: 233 DFELGEELAEADDFIK-SGGSAIVGPDGEVLAGPLWNEENILYADLDLN 280
>UniRef50_A6BCC3 Cluster: Carbon-nitrogen hydrolase family protein;
n=1; Vibrio parahaemolyticus AQ3810|Rep: Carbon-nitrogen
hydrolase family protein - Vibrio parahaemolyticus
AQ3810
Length = 167
Score = 67.7 bits (158), Expect = 5e-10
Identities = 37/122 (30%), Positives = 66/122 (54%), Gaps = 4/122 (3%)
Query: 119 QEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTI 178
QE + P+ FC +++ + + AE ++ LA + +VI E+ G+T
Sbjct: 40 QELFAAPY-FCKKQEAKYFELAEETANSHLIQEMSALAKELGVVIPVSYFEKA---GNTF 95
Query: 179 WNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRH 238
+N+ V+I+ G V+ +RK+HIP ++E Y+ G+TG V++TK+GK IC+ +
Sbjct: 96 FNSLVMIDADGTVLDNYRKSHIPDGPGYSEKYYFSPGDTGFKVWQTKFGKFGAGICWDQW 155
Query: 239 HP 240
P
Sbjct: 156 FP 157
>UniRef50_A1HPP3 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Thermosinus
carboxydivorans Nor1|Rep: Nitrilase/cyanide hydratase
and apolipoprotein N-acyltransferase - Thermosinus
carboxydivorans Nor1
Length = 259
Score = 67.7 bits (158), Expect = 5e-10
Identities = 54/209 (25%), Positives = 95/209 (45%), Gaps = 22/209 (10%)
Query: 146 GPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGD 205
GP+ L + A + I+ + +I ++NT VI+ G+V+GK+ K H+ V
Sbjct: 61 GPTVKMLQQFAKDNGVEIVGGSIA--EIRDGKVYNTIYVIDSAGEVVGKYSKIHL--VPM 116
Query: 206 FNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLS 265
+E Y G+ +F+ +GK +CY + GAE++F P+ +
Sbjct: 117 MDEEKYLTPGDR-QGLFDLSFGKAGGIVCYDLRFTELTRALALKGAEVLFIPAEWPAIRG 175
Query: 266 EHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDG 325
H W + ++ AI N + A+NRVG + H + F+G S V +P G
Sbjct: 176 RH-WLILSQARAIENQMFVVAVNRVGRD--------------HNN--TFFGHSLVVSPWG 218
Query: 326 SRTPGLSRIKDGLLIAQVDLNLCRQIKDK 354
S ++ ++IA +DL + +I+ K
Sbjct: 219 EVLAEGSETEEQVIIADIDLGMVPEIRRK 247
>UniRef50_Q8RUF8 Cluster: AT5g12040/F14F18_210; n=9;
Magnoliophyta|Rep: AT5g12040/F14F18_210 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 369
Score = 67.7 bits (158), Expect = 5e-10
Identities = 75/289 (25%), Positives = 120/289 (41%), Gaps = 39/289 (13%)
Query: 90 ITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTG--- 146
+T + +K I AA++ ++ L E WN P++ + +AE + G
Sbjct: 97 VTSDKKRNISHAKKAIEEAASKGAKLVLLPEIWNSPYS-----NDSFPVYAEEIDAGGDA 151
Query: 147 -PSTVFLAELAVKYDMVIIS-PILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH----- 199
PST L+E++ + + II I ER GD ++NT V G++ KHRK H
Sbjct: 152 SPSTAMLSEVSKRLKITIIGGSIPERV---GDRLYNTCCVFGSDGELKAKHRKIHLFDID 208
Query: 200 IPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSA 259
IP F ES G T + +T G++ I ICY +++ GA ++ P A
Sbjct: 209 IPGKITFMESKTLTAGET-PTIVDTDVGRIGIGICYDIRFQELAMIYAARGAHLLCYPGA 267
Query: 260 TVSGLSEHLWAVEARNAAIANSYY--TCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGS 317
W + R A N Y TC+ R SG G A +G
Sbjct: 268 FNMTTGPLHWELLQRARATDNQLYVATCSPAR----------DSGAGYTA-------WGH 310
Query: 318 SYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
S + P G + ++ ++IA++D ++ Q + +R DLY
Sbjct: 311 STLVGPFG-EVLATTEHEEAIIIAEIDYSILEQRRTSLPLNRQRRGDLY 358
>UniRef50_A3H7D3 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Caldivirga
maquilingensis IC-167|Rep: Nitrilase/cyanide hydratase
and apolipoprotein N-acyltransferase - Caldivirga
maquilingensis IC-167
Length = 279
Score = 66.9 bits (156), Expect = 8e-10
Identities = 50/152 (32%), Positives = 72/152 (47%), Gaps = 4/152 (2%)
Query: 140 AEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH 199
AEP L G S L E+A + II+ I ERD G ++N+AV I E G ++ +RK H
Sbjct: 59 AEP-LDGKSIGELTEIAREGKCTIITGIAERDKDTG-VVYNSAVAIGENG-LMALYRKRH 115
Query: 200 IPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSA 259
+P G F+ES Y+ G PVF K + ICY +P + GA + SA
Sbjct: 116 LPSYGVFDESRYFGVGRGDAPVFSMNGTKAGLAICYDAFYPEVSRSLMLKGARVQVYISA 175
Query: 260 TVSGLSEHLWAVEARNAAIANSYYTCAINRVG 291
+S + R A+ N + +N +G
Sbjct: 176 -APDMSRPHFETFIRARAMENVSFVIYVNTIG 206
>UniRef50_A7DPX6 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=2;
Crenarchaeota|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 268
Score = 66.5 bits (155), Expect = 1e-09
Identities = 52/194 (26%), Positives = 86/194 (44%), Gaps = 4/194 (2%)
Query: 99 EKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVK 158
+K+ I AA++ LC + M + ++ + AE + G +A A +
Sbjct: 19 KKIISFIEKAASKNAT-LCAFPEFMMFYTNSSQTPKQLATLAETI-NGNFVNTIANTAKE 76
Query: 159 YDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTG 218
+ ++ E+ D +++T+ VI++ GKVI +RK H+ F ES G+
Sbjct: 77 NHVQVVGSFYEKSR-KKDRVYDTSFVIDKTGKVISTYRKIHLYDALGFRESDKMASGSKI 135
Query: 219 HPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSG-LSEHLWAVEARNAA 277
+T GKV + ICY P G+E++ PSA V G + E W + A
Sbjct: 136 AKPVKTTIGKVGMMICYDLRFPEMSRSLAAAGSEVLVAPSAWVKGNMKEEHWITINKTRA 195
Query: 278 IANSYYTCAINRVG 291
I N Y A ++VG
Sbjct: 196 IENGCYVIAPDQVG 209
>UniRef50_A1S062 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Thermofilum
pendens Hrk 5|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Thermofilum pendens
(strain Hrk 5)
Length = 279
Score = 66.1 bits (154), Expect = 1e-09
Identities = 55/177 (31%), Positives = 80/177 (45%), Gaps = 25/177 (14%)
Query: 178 IWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHP-VFETKYGKVAINICYG 236
I+ +V + G V G K ++P G F ES Y+ EG+ VFE +VA IC
Sbjct: 92 IYENSVAVVRDGSVAGVVSKLYLPDYGLFEESRYFREGSCSREGVFECGGWRVAPIICED 151
Query: 237 RHHPLNWLMFGINGAEIVF-NPSATVSGLS-------EHLWAVEARNAAIANSYYTCAIN 288
HP + GA++VF + S+ + GL E +W A A+ N+ Y N
Sbjct: 152 AWHPEPAELAARRGADVVFIHASSPIRGLYGSGEANIERVWEAIAVTRAVENACYVVFAN 211
Query: 289 RVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDL 345
RVG E D +F+G S V APDG ++++ LL+A +DL
Sbjct: 212 RVGPE----------------DEEYFWGGSMVVAPDGEVVARAKKMEEELLVADLDL 252
>UniRef50_Q8W0T9 Cluster: Putative uncharacterized protein
SB35P03.20; n=1; Sorghum bicolor|Rep: Putative
uncharacterized protein SB35P03.20 - Sorghum bicolor
(Sorghum) (Sorghum vulgare)
Length = 580
Score = 64.5 bits (150), Expect = 4e-09
Identities = 46/183 (25%), Positives = 83/183 (45%), Gaps = 13/183 (7%)
Query: 106 SAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTG--PSTVFLAELAVKYDMVI 163
+AA + Q+ +E W+ C+ + +AE + G PS L+E+A + I
Sbjct: 372 AAAPSSQIKANMQKEIWS-----CSYAMETLASYAEDIDGGESPSISMLSEVAAAKKITI 426
Query: 164 ISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRV---GDFN-ESTYYFEGNTGH 219
+ + ++NT VI GK++ KHRK H+ + GD + + F G
Sbjct: 427 VGGSIPEKA--SGKMFNTCCVIGPDGKILAKHRKLHLFEIDIPGDITLKESDTFTGGQET 484
Query: 220 PVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIA 279
+ +T G++ I IC+ P +++ GA ++ PSA E LW + ++ A+
Sbjct: 485 TIVDTDVGRIGIGICHDIRFPELAMLYRSKGAHLICYPSAFNMSTGELLWDLMQKSRAVD 544
Query: 280 NSY 282
N +
Sbjct: 545 NQF 547
>UniRef50_UPI000051A529 Cluster: PREDICTED: similar to Nitrilase and
fragile histidine triad fusion protein CG7067-PA; n=1;
Apis mellifera|Rep: PREDICTED: similar to Nitrilase and
fragile histidine triad fusion protein CG7067-PA - Apis
mellifera
Length = 304
Score = 64.1 bits (149), Expect = 6e-09
Identities = 62/230 (26%), Positives = 94/230 (40%), Gaps = 23/230 (10%)
Query: 144 LTGPSTVFLAELA-VKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPR 202
L G + E+A + + + I E D + + I NT ++IN G+++ +RK H+
Sbjct: 85 LNGSTVTSYKEIAKINKIWLSLGGIHEALDNNREHISNTHILINSEGEIVSTYRKIHLFD 144
Query: 203 VGDFN------ESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFN 256
+ + N ES Y G P T GK+A++ICY P GAEI+
Sbjct: 145 MDNKNTGVRLMESDYVLPGQKIEPPISTPIGKLALSICYDMRFPELSFSLRNMGAEILTY 204
Query: 257 PSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYG 316
PSA W + R AI Y A + H +G
Sbjct: 205 PSAFTYQTGAAHWEILLRARAIETQCYVVAAAQTS---------------IHNKKRVSWG 249
Query: 317 SSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
+ V P GS S K +++A++DLNL +QI+ +R DLY
Sbjct: 250 HAMVIDPWGSIIAQCSE-KTDIILAEIDLNLLKQIRQNMPCENHRRTDLY 298
>UniRef50_Q54JM9 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 328
Score = 64.1 bits (149), Expect = 6e-09
Identities = 50/191 (26%), Positives = 82/191 (42%), Gaps = 12/191 (6%)
Query: 103 KIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMV 162
K I AA ++ L E +N P++ T EK + E V L+E A + +
Sbjct: 75 KHIDEAAKNGAKLISLPECFNSPYSTSTFEKYSETEDGETVKK------LSEAAKRNQIF 128
Query: 163 IISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH-----IPRVGDFNESTYYFEGNT 217
++ + D I+NT + N+ G+V+ KHRK H +P F ES G++
Sbjct: 129 LVGGSIPEIDKATGKIYNTCFIFNDKGEVVKKHRKIHLFDIDVPNKIRFKESETLTPGDS 188
Query: 218 GHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAA 277
V + Y K+ + ICY P +++ GA+ + P A W + R A
Sbjct: 189 -FSVVDIGYCKIGVAICYDIRFPELAMLYSKMGAKFLIYPGAFNMVTGPAHWELLQRGRA 247
Query: 278 IANSYYTCAIN 288
+ N + AI+
Sbjct: 248 VDNQVFVAAIS 258
>UniRef50_Q2NHR0 Cluster: Predicted amidohydrolase; n=1;
Methanosphaera stadtmanae DSM 3091|Rep: Predicted
amidohydrolase - Methanosphaera stadtmanae (strain DSM
3091)
Length = 274
Score = 64.1 bits (149), Expect = 6e-09
Identities = 49/193 (25%), Positives = 88/193 (45%), Gaps = 14/193 (7%)
Query: 99 EKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVK 158
E ++I A++ ++ L E +N P+ + + ++ E T + + ++A +
Sbjct: 22 EHAIQLIKKASSNGAKLITLPEMFNTPY-----DNSKFIEYCEEETTSKTLNSMQDIARE 76
Query: 159 YDMVIIS-PILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVG----DFNESTYYF 213
++ + S I E++ H ++NTA +IN GK+IGKHRK H+ + F ES
Sbjct: 77 ENIYLQSGSIPEKESNH---LYNTAYLINPKGKIIGKHRKMHMFDIDTDNMKFTESDTLT 133
Query: 214 EGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEA 273
G++ + +T ++I ICY P W + N ++I+ P A W
Sbjct: 134 PGDSVTTI-KTPLANISIAICYDIRFPELWTLMNKNNSDIILLPGAFNKTTGPLHWETLI 192
Query: 274 RNAAIANSYYTCA 286
+ AI N Y A
Sbjct: 193 KARAIDNQCYVVA 205
>UniRef50_Q1QTM0 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Chromohalobacter
salexigens DSM 3043|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Chromohalobacter
salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 260
Score = 63.7 bits (148), Expect = 8e-09
Identities = 56/211 (26%), Positives = 98/211 (46%), Gaps = 30/211 (14%)
Query: 138 DFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRK 197
+ AEPV GP AELA ++++ ++ + ER + N+AV+I++ G+ I + K
Sbjct: 55 ELAEPV-GGPIAQRAAELAAEHELFLLFGLAERQA--DGRLTNSAVLIDDRGERIATYHK 111
Query: 198 NHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNP 257
+ ++ +F V ET+ G++ + ICY P GA+++ +P
Sbjct: 112 RQL-----WDREHAFFAAGEDCCVVETRLGRLGLMICYDNEFPEVARALATQGAQVILSP 166
Query: 258 SATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGS 317
+A + +E A++ R A+ N + INR G E+ E H+ G+
Sbjct: 167 TANMVPNAER-QALQIRARALDNQCFVACINRAGEEA---EL-------------HYCGN 209
Query: 318 SYVTAPDGSRTPGLSRIKD--GLLIAQVDLN 346
S + PDG L R+ D G L+ +DL+
Sbjct: 210 SLIAGPDGE---VLGRLGDAAGSLVVDIDLS 237
>UniRef50_Q74H63 Cluster: Hydrolase, carbon-nitrogen family; n=8;
Desulfuromonadales|Rep: Hydrolase, carbon-nitrogen
family - Geobacter sulfurreducens
Length = 259
Score = 62.9 bits (146), Expect = 1e-08
Identities = 52/194 (26%), Positives = 87/194 (44%), Gaps = 17/194 (8%)
Query: 101 VQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVF-LAELAVKY 159
VQK + A++ + L E W+ +A+ + E P V L L+ +
Sbjct: 26 VQKALRRLASQGCRLAVLPEMWSTGYAYK--------ELNELAKRTPEVVAELGRLSREL 77
Query: 160 DMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGH 219
+MVI+ + E HG+ ++NTA V++ G+++G +RK H+ + + S +G
Sbjct: 78 EMVIVGSMPEP---HGEKVFNTAYVLDR-GELLGSYRKIHLFSLMGEDRS---LDGGDRW 130
Query: 220 PVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIA 279
V +T G++ + ICY P + GAEI+ P+ EH W R AI
Sbjct: 131 LVVDTHVGRLGVFICYDLRFPELARRLAVEGAEIIVVPAEWPKPREEH-WRALLRARAIE 189
Query: 280 NSYYTCAINRVGTE 293
N + A N G +
Sbjct: 190 NQLFVVAANCCGVQ 203
>UniRef50_Q84FR7 Cluster: D-N-carbamoylase; n=1; Arthrobacter
crystallopoietes|Rep: D-N-carbamoylase - Arthrobacter
crystallopoietes
Length = 315
Score = 62.5 bits (145), Expect = 2e-08
Identities = 50/200 (25%), Positives = 88/200 (44%), Gaps = 22/200 (11%)
Query: 179 WNTAVVINEFGKVIGKHRKNHIPRVGDFN--------ESTYYFEGNTGHPVFETKYGKVA 230
+NT++++N+ G ++GK+RK H+P D E Y+ EG+ G VF+ +V
Sbjct: 105 YNTSILVNKHGDIVGKYRKMHLPGHADNREGLPNQHLEKKYFREGDLGFGVFDFHGVQVG 164
Query: 231 INICYGRHHPLNWLMFGINGAEIV---FNPSATVSGLSEHLWAVEARNAAIANSYYTCAI 287
+ +C R P + + GAE+V +N V G E A +T +
Sbjct: 165 MCLCNDRRWPEVYRSLALQGAELVVLGYNTPDFVPGWQEEPHA----------KMFTHLL 214
Query: 288 NRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNL 347
+ + F + GK +D H G S V AP G + D +++ + D+++
Sbjct: 215 SLQAGAYQNSVFVAAAGKSGFEDGHHMIGGSAVAAPSGEILAKAAGEGDEVVVVKADIDM 274
Query: 348 CRQIKDK-WGFTMTQRLDLY 366
+ K+ + F +R D Y
Sbjct: 275 GKPYKESVFDFAAHRRPDAY 294
>UniRef50_Q18UU7 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=2;
Desulfitobacterium hafniense|Rep: Nitrilase/cyanide
hydratase and apolipoprotein N-acyltransferase -
Desulfitobacterium hafniense (strain DCB-2)
Length = 289
Score = 62.5 bits (145), Expect = 2e-08
Identities = 58/232 (25%), Positives = 101/232 (43%), Gaps = 22/232 (9%)
Query: 73 VRLGLIQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTRE 132
+R+GL Q + T++ L +++ + A+++ V++LC E A
Sbjct: 5 IRIGLAQFEAKVGD----TERNL---QEIIRTAEVASSQGVSLLCYPEC-----ALHGYS 52
Query: 133 KQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVI 192
+ + A+P L + L E A ++++ ++E+ + +V + +
Sbjct: 53 PKDASEIADP-LDSMAVARLRECARDLGLILLVGMVEKSPEGKKPYISQLIVFPDREPEV 111
Query: 193 GKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAE 252
+RK H+ R+ +YF P+F K +I IC+ H P + + GAE
Sbjct: 112 --YRKVHLGRI-----EQHYFTAGDSFPIFAAGGVKFSIGICWDWHFPELSAICSLKGAE 164
Query: 253 IVFNPSAT--VSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSG 302
I F P A+ VSG + +W A NS Y CA N VGT + EF+ G
Sbjct: 165 IQFAPHASPVVSGDRKEIWKRYLGARAYDNSVYLCACNLVGTNNRDKEFSGG 216
>UniRef50_Q75TH8 Cluster: Putative uncharacterized protein GSB07;
n=1; Geobacillus stearothermophilus|Rep: Putative
uncharacterized protein GSB07 - Bacillus
stearothermophilus (Geobacillus stearothermophilus)
Length = 273
Score = 62.1 bits (144), Expect = 2e-08
Identities = 60/227 (26%), Positives = 106/227 (46%), Gaps = 30/227 (13%)
Query: 146 GPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGD 205
G + +++LA + + + +E+D H ++N+ ++I+ G+ IG +RK H+
Sbjct: 68 GSTFQHMSQLAQTFQLYLAYGYVEKD--HTGNLYNSLMLIDPNGQCIGNYRKIHLTPF-- 123
Query: 206 FNESTYYFEGNTGHPVF-ETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGL 264
E ++ +G PV +T+ G++ + IC+ P ++GAE++ P A S
Sbjct: 124 --EKAWFSKG--AEPVLVDTELGRIGLMICWDLAFPELARYLAVHGAELLLVPCAWESPF 179
Query: 265 SEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPD 324
A AI N+ Y A N++G+ S F HF+G S + PD
Sbjct: 180 HAPFQKF-AMARAIDNTVYVAACNQIGSSS---SF-------------HFFGLSSIYGPD 222
Query: 325 GSRTPGLS-RIKDGLLIAQVDLNLCRQIKDKWGFTM--TQRLDLYAQ 368
G + + ++ L+ A +D N RQ K +TM +R+DLY Q
Sbjct: 223 GRKIAAANMNGREELVHAMIDQNQ-RQALKKHFYTMMDERRIDLYRQ 268
>UniRef50_Q86X76 Cluster: Nitrilase homolog 1; n=29; Eumetazoa|Rep:
Nitrilase homolog 1 - Homo sapiens (Human)
Length = 327
Score = 61.7 bits (143), Expect = 3e-08
Identities = 58/194 (29%), Positives = 77/194 (39%), Gaps = 21/194 (10%)
Query: 178 IWNTAVVINEFGKVIGKHRKNH-----IPRVGDFNESTYYFEGNTGHPVFETKYGKVAIN 232
I+N V++N G V+ +RK H IP G ES G + T GK+ +
Sbjct: 142 IYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVSTPAGKIGLA 201
Query: 233 ICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGT 292
+CY P L GAEI+ PSA S W V R AI Y A + G
Sbjct: 202 VCYDMRFPELSLALAQAGAEILTYPSAFGSITGPAHWEVLLRARAIETQCYVVAAAQCG- 260
Query: 293 ESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIK 352
H + YG S V P G+ S GL +A++DLN RQ++
Sbjct: 261 --------------RHHEKRASYGHSMVVDPWGTVVARCSE-GPGLCLARIDLNYLRQLR 305
Query: 353 DKWGFTMTQRLDLY 366
+R DLY
Sbjct: 306 RHLPVFQHRRPDLY 319
>UniRef50_A2XD42 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. indica (Rice)
Length = 349
Score = 61.3 bits (142), Expect = 4e-08
Identities = 71/293 (24%), Positives = 120/293 (40%), Gaps = 26/293 (8%)
Query: 90 ITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTG--- 146
+T + + ++ I AAAA ++ L E WN P++ + ++AE + G
Sbjct: 55 VTADKARNIARAREAIEAAAAGGAKLVLLPEIWNGPYS-----NDSFPEYAEDIEAGGDA 109
Query: 147 -PSTVFLAELAVKYDMVIIS-PILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH----- 199
PS ++E+A + ++ I ER G+ ++NT V G++ GKHRK H
Sbjct: 110 APSFSMMSEVARSLQITLVGGSISERS---GNKLYNTCCVFGSDGELKGKHRKIHLFDID 166
Query: 200 IPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSA 259
IP F ES G V +T G++ I ICY +++ GA ++ P A
Sbjct: 167 IPGKITFKESKTLTAGQ-DLTVVDTDVGRIGIGICYDIRFQELAMLYAARGAHLLCYPGA 225
Query: 260 TVSGLSEHLWAVEARNAAIANSYYTCAI-NRVGTES---FPNEFTSGDGKPAHKDFGHF- 314
W + R A N + N V + S F + PA +
Sbjct: 226 FNMTTGPLHWELLQRARAADNQKLIIHVANLVVSNSNRTFCYQLFVATCAPARDTSAGYI 285
Query: 315 -YGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
+G S + P G + ++ ++A++D +L Q + +R DLY
Sbjct: 286 AWGHSTLVGPFG-EVIATAEHEETTIMAEIDYSLIDQRRQFLPLQYQRRGDLY 337
>UniRef50_Q6TGW8 Cluster: Nit protein 2; n=22; Fungi/Metazoa
group|Rep: Nit protein 2 - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 277
Score = 60.9 bits (141), Expect = 5e-08
Identities = 66/273 (24%), Positives = 115/273 (42%), Gaps = 30/273 (10%)
Query: 100 KVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKY 159
+ Q +++ AA + ++ L E +N P+ + ++AE + G ST L+E A K
Sbjct: 23 RAQTLVTEAAGQGAKVVVLPECFNSPYGTGFFK-----EYAEKI-PGESTQVLSETAKKC 76
Query: 160 DMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH-----IPRVGDFNESTYYFE 214
+ ++ + +D G ++NT V G ++ HRK H +P F ES
Sbjct: 77 GIYLVGGSIPEED--GGKLYNTCSVFGPDGTLLVTHRKIHLFDIDVPGKIRFQESETLSP 134
Query: 215 GNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEAR 274
G + +FET Y KV + ICY ++ G +++ P A W + R
Sbjct: 135 GKS-LSMFETPYCKVGVGICYDIRFAELAQIYAKKGCQLLVYPGAFNMTTGPAHWELLQR 193
Query: 275 NAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRI 334
A+ N Y V T S + D ++ +GH S V P G +
Sbjct: 194 GRAVDNQVY------VATAS-----PARDETASYVAWGH----SSVINPWG-EVISKAGS 237
Query: 335 KDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLYA 367
++ ++ A +DL ++ + T +R DLY+
Sbjct: 238 EESVVYADIDLQYLADVRQQIPITKQRRNDLYS 270
>UniRef50_Q9ZMC7 Cluster: Putative; n=6; Campylobacterales|Rep:
Putative - Helicobacter pylori J99 (Campylobacter pylori
J99)
Length = 294
Score = 60.9 bits (141), Expect = 5e-08
Identities = 56/242 (23%), Positives = 109/242 (45%), Gaps = 29/242 (11%)
Query: 114 NILCLQEAWNMPFAFCTREKQPWCDF-----AEPVLTGPSTVFLAELAVKYDMVIISPIL 168
N++ L E ++ + ++ DF E L + L++ A D I++ +
Sbjct: 45 NLIVLPELFDSGYCVNDKDADFGLDFKAIEHGEETLKNETLRALSDFAKSSDTHIVACSI 104
Query: 169 ERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYG- 227
E+++ ++++A +I GK++GKHRK ++ + + F+ + VF +G
Sbjct: 105 EKNN---KKLYDSAYIIPPKGKIVGKHRKIYL-----WGDEKSRFKRGKKYEVFTLDFGD 156
Query: 228 ---KVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYT 284
KV + ICY + + + GAE++ PSA + W + ++ A+ N +
Sbjct: 157 FSAKVGLQICYETGFGVGANLLVLQGAEVLIYPSA-FGKARAYNWDLLSKARALENGCFV 215
Query: 285 CAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVD 344
CA N G E+ K F G S + AP+G +++ + ++IA++D
Sbjct: 216 CACNHSGEET----------NAKLKQTLEFAGDSRIIAPNGKIIAQATKLNE-VIIAEMD 264
Query: 345 LN 346
LN
Sbjct: 265 LN 266
>UniRef50_Q8WUF0 Cluster: Nitrilase family member 2; n=28; cellular
organisms|Rep: Nitrilase family member 2 - Homo sapiens
(Human)
Length = 276
Score = 60.5 bits (140), Expect = 7e-08
Identities = 75/305 (24%), Positives = 131/305 (42%), Gaps = 40/305 (13%)
Query: 74 RLGLIQHSIA-ISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTRE 132
RL LIQ I+ I +DN +T + I AA + I+ L E +N P+
Sbjct: 5 RLALIQLQISSIKSDN-VT--------RACSFIREAATQGAKIVSLPECFNSPYG----- 50
Query: 133 KQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVI 192
+ + ++AE + G ST L+E+A + + +I + +D ++NT V G ++
Sbjct: 51 AKYFPEYAEKI-PGESTQKLSEVAKECSIYLIGGSIPEED--AGKLYNTCAVFGPDGTLL 107
Query: 193 GKHRKNH-----IPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFG 247
K+RK H +P F ES G++ F+T Y +V + ICY ++
Sbjct: 108 AKYRKIHLFDIDVPGKITFQESKTLSPGDS-FSTFDTPYCRVGLGICYDMRFAELAQIYA 166
Query: 248 INGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPA 307
G +++ P A W + R+ A+ N Y V T S + D K +
Sbjct: 167 QRGCQLLVYPGAFNLTTGPAHWELLQRSRAVDNQVY------VATAS-----PARDDKAS 215
Query: 308 HKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLYA 367
+ +GH S V P G + ++ ++ + +DL +I+ + +R DLYA
Sbjct: 216 YVAWGH----STVVNPWGEAL-AKAGTEEAIVYSDIDLKKLAEIRQQIPVFRQKRSDLYA 270
Query: 368 QSLNE 372
+ +
Sbjct: 271 VEMKK 275
>UniRef50_A2BNC1 Cluster: Predicted amidohydrolase; n=1;
Hyperthermus butylicus DSM 5456|Rep: Predicted
amidohydrolase - Hyperthermus butylicus (strain DSM 5456
/ JCM 9403)
Length = 269
Score = 60.5 bits (140), Expect = 7e-08
Identities = 36/124 (29%), Positives = 63/124 (50%), Gaps = 2/124 (1%)
Query: 140 AEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH 199
AEP L GP F A LA +Y + +++ + E+ G +NTA +I G+++ +RK H
Sbjct: 63 AEP-LEGPWIGFFARLAREYSVHVVATLYEKSKAGGKP-YNTAALIAPTGELLAVYRKIH 120
Query: 200 IPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSA 259
+ + ES Y+ G + K ++A+ +C+ P + + + GAE+V P+A
Sbjct: 121 LFDAYGYRESDYFMPGAEPAKLATIKGFRIALAVCFDLRFPELFRTYALQGAELVAVPAA 180
Query: 260 TVSG 263
G
Sbjct: 181 WYRG 184
>UniRef50_Q0RPB5 Cluster: Putative methylthioribose recycling
protein; n=1; Frankia alni ACN14a|Rep: Putative
methylthioribose recycling protein - Frankia alni
(strain ACN14a)
Length = 262
Score = 60.1 bits (139), Expect = 1e-07
Identities = 54/198 (27%), Positives = 93/198 (46%), Gaps = 13/198 (6%)
Query: 96 AIFEKVQKIISAAAAEQVNILCLQEAWNMP-FAFCTREKQPWCDFAEPVLTGPSTVFLAE 154
++ ++V+++++ + +++ L E W F F + Q AEP LTGP+ L E
Sbjct: 12 SVADRVRRVLADLRSTDADLVVLPELWATGYFRFDAYQAQ-----AEP-LTGPTLTALRE 65
Query: 155 LAVKYDMVIIS-PILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYF 213
+A + +++ ++ER D + NT +I G ++ +RK H+ G +E+
Sbjct: 66 VARERRFHLVAGSLVERAD--DGRLHNTTALIGPGGDILHTYRKIHLFGYGS-DEARLLT 122
Query: 214 EGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEA 273
G T V T+ G + + CY P + + G GA++V SA + EH W V
Sbjct: 123 PGTTVDAV-RTELGCIGLATCYDLRFPELFRLLGDAGADLVAVVSAWPAARLEH-WRVLT 180
Query: 274 RNAAIANSYYTCAINRVG 291
R AI N + A N G
Sbjct: 181 RARAIENQVHLVACNVAG 198
>UniRef50_UPI0000E1FE2F Cluster: PREDICTED: similar to Nitrilase
family, member 2; n=2; Coelomata|Rep: PREDICTED: similar
to Nitrilase family, member 2 - Pan troglodytes
Length = 411
Score = 59.7 bits (138), Expect = 1e-07
Identities = 75/305 (24%), Positives = 130/305 (42%), Gaps = 40/305 (13%)
Query: 74 RLGLIQHSIA-ISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTRE 132
RL LIQ I+ I +DN +T + I AA + I+ L E +N P+
Sbjct: 140 RLALIQLQISSIKSDN-VT--------RACSFIREAATQGAKIVSLPECFNSPYG----- 185
Query: 133 KQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVI 192
+ + ++AE + G ST L E+A + + +I + +D ++NT V G ++
Sbjct: 186 TKYFPEYAEKI-PGESTQKLCEVAKECSIYLIGGSIPEED--AGKLYNTCAVFGPDGTLL 242
Query: 193 GKHRKNH-----IPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFG 247
K+RK H +P F ES G++ F+T Y +V + ICY ++
Sbjct: 243 AKYRKIHLFDIDVPGKITFQESKTLSPGDS-FSTFDTPYCRVGLGICYDMRFAELAQIYA 301
Query: 248 INGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPA 307
G +++ P A W + R+ A+ N Y V T S + D K +
Sbjct: 302 QRGCQLLVYPGAFNLTTGPAHWELLQRSRAVDNQVY------VATAS-----PARDDKAS 350
Query: 308 HKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLYA 367
+ +GH S V P G + ++ ++ + +DL +I+ + +R DLYA
Sbjct: 351 YVAWGH----STVVNPWG-EVLAKAGTEEAIVYSDIDLKKLAEIRQQIPVFRQKRSDLYA 405
Query: 368 QSLNE 372
+ +
Sbjct: 406 VEMKK 410
>UniRef50_A4EPU1 Cluster: Putative hydrolase; n=2;
Rhodobacteraceae|Rep: Putative hydrolase - Roseobacter
sp. SK209-2-6
Length = 264
Score = 59.7 bits (138), Expect = 1e-07
Identities = 76/251 (30%), Positives = 107/251 (42%), Gaps = 42/251 (16%)
Query: 101 VQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYD 160
+++ +S + V++L L E + + +R D AEP GPS +AELA +
Sbjct: 26 LRECLSQLDGQHVDLLLLPELFLTGYNIGSRVT----DRAEPA-DGPSAQAIAELARAHR 80
Query: 161 MVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHP 220
+ I ER D I+N+A I++ G ++ HRK +P F E ++ G G+
Sbjct: 81 IAIHYGFAERQD---GQIFNSASCISKDGTLLATHRKLLLPP--GF-EGDHFCPG-IGYT 133
Query: 221 VFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNA---- 276
FE VA ICY P + GAE+V P+A + W V A
Sbjct: 134 QFELNGFNVATLICYDAEFPETFRAVAQAGAELVLVPTALGA-----QWGVVANTVIPAR 188
Query: 277 AIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKD 336
A N Y C N G H++ FYG S V APDG L+R D
Sbjct: 189 AFENGIYVCYANSCG----------------HENGMDFYGGSCVIAPDGQE---LARAGD 229
Query: 337 G--LLIAQVDL 345
G LL AQ +L
Sbjct: 230 GEELLRAQANL 240
>UniRef50_A0TTW8 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=5;
Proteobacteria|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Burkholderia
cenocepacia MC0-3
Length = 299
Score = 59.7 bits (138), Expect = 1e-07
Identities = 46/154 (29%), Positives = 78/154 (50%), Gaps = 10/154 (6%)
Query: 105 ISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVII 164
I AA ++ L E + + F R++ AE V GP+ +A + ++ I+
Sbjct: 42 IETAARNGAALIVLPELASSGYVFEDRDEA--LALAELVPDGPTARAFEAIARRLNVHIV 99
Query: 165 SPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFET 224
S I ERD G ++N+A+ G +G +RK H+ D NE ++ G+ G PVF+T
Sbjct: 100 SGIAERD---GARLYNSALFAGPGGH-LGVYRKLHL---WD-NEKRFFEPGDRGVPVFDT 151
Query: 225 KYGKVAINICYGRHHPLNWLMFGINGAEIVFNPS 258
G++A+ ICY P + + + GA++V P+
Sbjct: 152 PLGRIAMAICYDVWFPETFRLAVMQGADLVCVPT 185
>UniRef50_Q9KE11 Cluster: BH1047 protein; n=1; Bacillus
halodurans|Rep: BH1047 protein - Bacillus halodurans
Length = 271
Score = 59.3 bits (137), Expect = 2e-07
Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 5/142 (3%)
Query: 150 VFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNES 209
+FL ELA ++++ I++ + + + ++N A+V + G + ++ K H+ V +E
Sbjct: 67 LFLKELAREHNVNIVAGSIAKKE--KGKLYNRALVFDRRGHTVYQYDKIHL--VPMLSEP 122
Query: 210 TYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLW 269
Y G+ VFE + K+ + ICY P + GAEIVF + + H W
Sbjct: 123 DYLTGGDAAASVFELEGTKMGLVICYDLRFPELMRSLALEGAEIVFIVAEWPEARAVH-W 181
Query: 270 AVEARNAAIANSYYTCAINRVG 291
V R AI N Y + NRVG
Sbjct: 182 EVLQRARAIENQSYVISCNRVG 203
>UniRef50_Q89E80 Cluster: Bll7207 protein; n=1; Bradyrhizobium
japonicum|Rep: Bll7207 protein - Bradyrhizobium
japonicum
Length = 307
Score = 59.3 bits (137), Expect = 2e-07
Identities = 50/202 (24%), Positives = 90/202 (44%), Gaps = 20/202 (9%)
Query: 179 WNTAVVINEFGKVIGKHRKNHI-----PRVG---DFNESTYYFEGNTGHPVFET----KY 226
+N A++++ G+++G++RK H+ PR G E Y+ G+ G P F +
Sbjct: 94 YNCAILVDRDGEILGRYRKVHLPGSVEPRPGARYQQLEKRYFEYGDLGFPAFRAGSAWAH 153
Query: 227 GKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCA 286
+ + IC R P +W + G+ G E+V + + A E + A+ + T
Sbjct: 154 AIMGMMICNDRRWPESWRVLGLQGVELVC-IGYNSAAYDPNGGATE--DGALRTFHSTLV 210
Query: 287 INRVGTESFPN-EFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDL 345
++ N + K +D G S + P+G + D +++A +DL
Sbjct: 211 TQ---ANAYMNATWAISVAKAGEEDGSGLIGGSCIVDPNGRIVAQAQTLADEVVVADIDL 267
Query: 346 NLCRQIKDK-WGFTMTQRLDLY 366
+LCRQ KDK + F +R + Y
Sbjct: 268 DLCRQGKDKMFNFAAHRRPEQY 289
>UniRef50_Q6L0F7 Cluster: Carbon-nitrogen hydrolase family; n=2;
Thermoplasmatales|Rep: Carbon-nitrogen hydrolase family
- Picrophilus torridus
Length = 256
Score = 59.3 bits (137), Expect = 2e-07
Identities = 48/193 (24%), Positives = 92/193 (47%), Gaps = 11/193 (5%)
Query: 99 EKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVK 158
EK++K AA+ +++ E F F + +K+ + AEP+ + +++ +
Sbjct: 20 EKLRKYTEIAASNGADLIVFPEY----FMFYSNDKKYLNENAEPI----NGIWVKNVIKI 71
Query: 159 YDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTG 218
++ IS I+ ++++ + +++TAV I+ G V G +RK + + ES Y GN
Sbjct: 72 FNENSISGIVCINELNDNNVFDTAVYIS--GDVKGYYRKKMLYDAFGYRESDIYKSGNGP 129
Query: 219 HPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSG-LSEHLWAVEARNAA 277
++ I ICY P + + NGA+++ PS SG + E W R A
Sbjct: 130 FNLYRINDISFGILICYEIRFPELFRNYSKNGADMIIIPSGWFSGPVKEEQWLSLLRARA 189
Query: 278 IANSYYTCAINRV 290
+ N+ Y + N++
Sbjct: 190 LENTVYIASSNQI 202
>UniRef50_A4SZC4 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase precursor; n=1;
Polynucleobacter sp. QLW-P1DMWA-1|Rep: Nitrilase/cyanide
hydratase and apolipoprotein N-acyltransferase precursor
- Polynucleobacter sp. QLW-P1DMWA-1
Length = 622
Score = 58.0 bits (134), Expect = 4e-07
Identities = 46/163 (28%), Positives = 77/163 (47%), Gaps = 10/163 (6%)
Query: 100 KVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQ-PWCDFAEPVLTGPSTVFLAELAVK 158
K+ I + AA ++ E + F + T E+ P D G +T ++A K
Sbjct: 42 KMADISADAAKNGAKLIVFPEMASTGFLYMTLEQAGPNVD----TFPGKATAAFGQVAQK 97
Query: 159 YDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTG 218
Y+ I +E D G +N+A ++ G G +RK+ + VGD N + GN G
Sbjct: 98 YNTYIAWGYIELDPKTG-VAYNSAAIVGPNG-FSGNYRKHQLA-VGDDN--LFRAPGNIG 152
Query: 219 HPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATV 261
PVF T GK+A+ +CY + L+ + A+I+ P+A++
Sbjct: 153 FPVFNTPIGKIALLVCYDDSQLQSLLLPALRNADIIAYPTASL 195
Score = 41.1 bits (92), Expect = 0.048
Identities = 30/93 (32%), Positives = 49/93 (52%), Gaps = 9/93 (9%)
Query: 139 FAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKN 198
FAEP L G S + LA K+ + ++ + E D + TA++ + GK IG +RK+
Sbjct: 373 FAEP-LNGKSYNIASSLAKKFQVNLLFSMPEITD---GKYYETAILFDYTGKQIGLYRKS 428
Query: 199 HIPRVGDFNESTYYFEGNTGHPVFETKYGKVAI 231
H+ + E T+ GN PVF + G++A+
Sbjct: 429 HLNDI----EKTWATAGNE-LPVFNSSIGRIAV 456
>UniRef50_Q1AWK1 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=4; Bacteria|Rep:
Nitrilase/cyanide hydratase and apolipoprotein
N-acyltransferase - Rubrobacter xylanophilus (strain DSM
9941 / NBRC 16129)
Length = 276
Score = 57.6 bits (133), Expect = 5e-07
Identities = 64/270 (23%), Positives = 117/270 (43%), Gaps = 29/270 (10%)
Query: 102 QKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDM 161
+ +I AAA ++ L E W+ C ++ + + AEP+ GP+T FL LA + +
Sbjct: 27 EALIREAAAAGATLVALPELWS-----CHGLEEVYRENAEPI-PGPTTEFLGSLARELGI 80
Query: 162 VIIS-PILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNT--G 218
++ ILER + + NT+ + G ++ +RK H+ V + + Y N G
Sbjct: 81 YLLGGSILERVS-GSERLGNTSTLYAPDGSLVAVYRKVHLFDV-EVSGRRYLESANIAPG 138
Query: 219 HPVFETKYGKVAI--NICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNA 276
K G V + ++CY P + + + GAE++ P+A + W + R
Sbjct: 139 GEAVAAKAGPVTVGLSVCYDVRFPELYRLLALRGAEVLAVPAAFTLQTGKDHWELLLRAR 198
Query: 277 AIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKD 336
A+ N Y A + G ++ DG+ YG S + P G+ +D
Sbjct: 199 AVENQAYVLAPAQWGRKA--------DGR-------WTYGRSMIVDPWGT-VLSTCPDRD 242
Query: 337 GLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
G +A +DL +++ ++ +R +Y
Sbjct: 243 GYALATLDLGYLERLRAEFPSLANRRPRVY 272
>UniRef50_A4YP30 Cluster: N-carbamoyl-D-amino acid hydrolase; n=4;
Proteobacteria|Rep: N-carbamoyl-D-amino acid hydrolase -
Bradyrhizobium sp. (strain ORS278)
Length = 332
Score = 57.6 bits (133), Expect = 5e-07
Identities = 52/202 (25%), Positives = 89/202 (44%), Gaps = 20/202 (9%)
Query: 179 WNTAVVINEFGKVIGKHRKNHI-----PRVG---DFNESTYYFEGNTGHPVFET--KYGK 228
+N+A++++ G++I K+RK H+ PR G E Y+ G+ G P ++G
Sbjct: 94 FNSAILVDADGQLISKYRKVHLPGSVEPREGARYQQLEKRYFGYGDLGFPAVRAGPEWGG 153
Query: 229 --VAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCA 286
+ + IC R P +W M G+ G E+V G + + N A+ +
Sbjct: 154 AIMGMMICNDRRWPESWRMLGMQGVELV------CVGYNSAAYDPNGGNTEDASLRTFHS 207
Query: 287 INRVGTESFPN-EFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDL 345
++ N + K +D G S + P+G + + D +L+A +DL
Sbjct: 208 TLVAQANAYMNATWAIAVAKAGDEDGSGLIGGSCIVDPNGCIVAQATTLADEVLVADIDL 267
Query: 346 NLCRQIKDK-WGFTMTQRLDLY 366
+ CRQ KDK + F +R D Y
Sbjct: 268 DACRQGKDKMFNFAAHRRPDQY 289
>UniRef50_Q8ZVX6 Cluster: Nitrilase, conjectural; n=4;
Pyrobaculum|Rep: Nitrilase, conjectural - Pyrobaculum
aerophilum
Length = 258
Score = 57.6 bits (133), Expect = 5e-07
Identities = 36/133 (27%), Positives = 63/133 (47%), Gaps = 3/133 (2%)
Query: 152 LAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTY 211
LA++A + + LER ++NT V+++ GK +G +RK H+ + ES
Sbjct: 61 LAKIAAETGAYVAGGFLERGP--RPKVFNTTVLVSPAGKAVGTYRKTHLFDAYGYKESEA 118
Query: 212 YFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSG-LSEHLWA 270
G +F+ + K+ +C+ P + + GA++V P+A SG L E +
Sbjct: 119 VEPGGELSGIFDVRQIKIGFAVCFELRFPEVFRELALGGAQLVAVPAAWYSGPLKEEILH 178
Query: 271 VEARNAAIANSYY 283
V AR A+ N +
Sbjct: 179 VLARARAVENGVF 191
>UniRef50_A3TQB8 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Janibacter sp.
HTCC2649|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Janibacter sp.
HTCC2649
Length = 310
Score = 57.2 bits (132), Expect = 7e-07
Identities = 40/150 (26%), Positives = 70/150 (46%), Gaps = 4/150 (2%)
Query: 144 LTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRV 203
L GP T +A + +V+ ER G ++N +V+IN G+++G +RK H
Sbjct: 72 LPGPMTAPFQAVARELGIVLCVGTYERGPERG-IVYNASVLINSDGELLGVYRKTHPFCT 130
Query: 204 GDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSG 263
+ + G+T V +T G++ + IC+ +P + + GAEI+ PSA +
Sbjct: 131 EAVSGGGWVTPGDTV-TVCDTAIGRIGMIICFDGDYPELSRIQAVQGAEIICRPSALLR- 188
Query: 264 LSEHLWAVEARNAAIANSYYTCAINRVGTE 293
S +W + +R A N + N G +
Sbjct: 189 -SADIWELTSRARAYDNHVFVIGANATGID 217
>UniRef50_P46011 Cluster: Nitrilase 4; n=49; cellular organisms|Rep:
Nitrilase 4 - Arabidopsis thaliana (Mouse-ear cress)
Length = 355
Score = 57.2 bits (132), Expect = 7e-07
Identities = 55/205 (26%), Positives = 86/205 (41%), Gaps = 16/205 (7%)
Query: 146 GPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGD 205
GP LA +A KY + ++ ++ER+ G T++ T + + G +GKHRK +P
Sbjct: 115 GPEVERLALMAKKYKVYLVMGVIERE---GYTLYCTVLFFDSQGLFLGKHRKL-MPTA-- 168
Query: 206 FNESTYYFEGNTGHPVFETKYGKVAINICYGRHHP-LNWLMFGINGAEIVFNPSATVSGL 264
+ F + PVF+T GK+ IC+ P L M+ G EI P+A
Sbjct: 169 LERCIWGFGDGSTIPVFDTPIGKIGAAICWENRMPSLRTAMYA-KGIEIYCAPTAD---- 223
Query: 265 SEHLWAVEARNAAIANSYYTCAIN----RVGTESFPNEFTSGDGKPAHKDFGHFYGSSYV 320
S W + A+ + + N R S P SG + D G S +
Sbjct: 224 SRETWLASMTHIALEGGCFVLSANQFCRRKDYPSPPEYMFSGSEESLTPDSVVCAGGSSI 283
Query: 321 TAPDGSRTPGLSRIKDGLLIAQVDL 345
+P G G + + L+ A +DL
Sbjct: 284 ISPLGIVLAGPNYRGEALITADLDL 308
>UniRef50_Q2JDM2 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=12;
Actinomycetales|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Frankia sp. (strain
CcI3)
Length = 404
Score = 56.8 bits (131), Expect = 9e-07
Identities = 53/196 (27%), Positives = 84/196 (42%), Gaps = 9/196 (4%)
Query: 99 EKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVK 158
++V++++ Q +++ L E W + R + AE LTGP+ L E A +
Sbjct: 22 DRVRRVLGEIRQTQADLVVLPELWVTGYFHFDRYEAE----AE-ALTGPTVTALREAARE 76
Query: 159 YDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTG 218
+++ + G ++NT V+I G + +RK H+ G E+ G T
Sbjct: 77 RGCHLVAGSIVERSADG-RLFNTTVLIGPDGMIRHAYRKVHLFGYGSA-EARLLTPGATV 134
Query: 219 HPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAI 278
V T+ G V + CY P + + GAEIV SA +H W V R AI
Sbjct: 135 GTV-PTELGIVGLATCYDLRFPELFRLLAEGGAEIVVVVSAWPLARLDH-WRVLTRTRAI 192
Query: 279 ANSYYTCAINRVGTES 294
N Y A N G ++
Sbjct: 193 ENQVYLVACNAAGRQA 208
>UniRef50_Q0S9Y1 Cluster: Possible nitrilase; n=4;
Actinomycetales|Rep: Possible nitrilase - Rhodococcus
sp. (strain RHA1)
Length = 270
Score = 56.8 bits (131), Expect = 9e-07
Identities = 51/196 (26%), Positives = 85/196 (43%), Gaps = 10/196 (5%)
Query: 99 EKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVK 158
E+V+ +++ A E+V+++ L E W + + + AE L G + LA +AV+
Sbjct: 21 ERVRNLLTGLA-ERVDLIVLPELWRVGY----NHFDDYSTAAE-TLGGGTVQVLAAVAVE 74
Query: 159 YDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTG 218
I + + G + NTAV+I G++ + K H+ D E+ G
Sbjct: 75 RQCYIHAGSIVEQGEEG-RLRNTAVLIGPDGQIHHHYSKVHVFGY-DSLEAQLLQPGTQI 132
Query: 219 HPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAI 278
H +T +G +A CY P W GA++V P+A EH W + A+
Sbjct: 133 HTT-DTPFGPIAATTCYDLRFPGLWTELVAAGAQLVIVPAAWPKARKEH-WRLLTSARAV 190
Query: 279 ANSYYTCAINRVGTES 294
N + A N GT +
Sbjct: 191 DNQVFVIACNATGTHN 206
>UniRef50_Q5WM18 Cluster: Methylthioribose recycling protein; n=2;
Bacillaceae|Rep: Methylthioribose recycling protein -
Bacillus clausii (strain KSM-K16)
Length = 275
Score = 56.4 bits (130), Expect = 1e-06
Identities = 57/222 (25%), Positives = 99/222 (44%), Gaps = 22/222 (9%)
Query: 146 GPSTV-FLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVG 204
G T+ FL +LA + + +++ + G I+NTA+VI+ GK++ + K H+ V
Sbjct: 74 GVETIAFLQQLARAHRIHMVAGSIATKKDGG--IYNTALVIDAQGKLVYTYDKVHL--VP 129
Query: 205 DFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGL 264
NE Y G+ +FE K+A+ ICY P + GAE++F +
Sbjct: 130 MLNEPAYMQGGSVPPALFELDGVKMAVLICYDLRFPELARRLALEGAEVLFIVAEWPLAR 189
Query: 265 SEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPD 324
+ H W + AI N +Y + N VG+ + + + G+S V P
Sbjct: 190 AMH-WKALQQARAIENQFYLLSCNSVGSHNGTD----------------YAGTSMVIDPW 232
Query: 325 GSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
G S ++ L +VD + +++D+ ++R DLY
Sbjct: 233 GEIIVEGSSTEEEWLQCKVDFSKAAEVRDRVPVFSSRRPDLY 274
>UniRef50_Q2S2E4 Cluster: Hydrolase, carbon-nitrogen family; n=1;
Salinibacter ruber DSM 13855|Rep: Hydrolase,
carbon-nitrogen family - Salinibacter ruber (strain DSM
13855)
Length = 281
Score = 56.4 bits (130), Expect = 1e-06
Identities = 56/211 (26%), Positives = 92/211 (43%), Gaps = 23/211 (10%)
Query: 95 LAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAE 154
L + + + + S + + +++ L E + + F + K AEP+ G S L
Sbjct: 15 LEVDQNLAAVESLLRSVEADLIVLPELFTSGYFF--QSKDDLERVAEPIPNGKSVAALRG 72
Query: 155 LAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFE 214
A +++ + ERD GD +N+AVV+ G+V +RK H+ F E T FE
Sbjct: 73 WADSLGATLVAGLAERD---GDHFYNSAVVVRPDGRV-DTYRKVHL-----FYEETILFE 123
Query: 215 -GNTGHPVFE------TKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEH 267
G+ G VFE T Y ++ + +C+ + P + GA+++ +PS V
Sbjct: 124 AGDLGFRVFEEHTAAGTSY-RLGVMVCFDWYFPEAARTLALRGADVIAHPSNLVLPHCPD 182
Query: 268 LWAVEARNAAIANSYYTCAINRVGTESFPNE 298
V AR N +T NR G E E
Sbjct: 183 SMPVRARE----NHVFTITANRHGREEKEGE 209
>UniRef50_A5V6Z2 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Sphingomonas
wittichii RW1|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Sphingomonas
wittichii RW1
Length = 384
Score = 56.4 bits (130), Expect = 1e-06
Identities = 53/176 (30%), Positives = 78/176 (44%), Gaps = 17/176 (9%)
Query: 144 LTGPSTVFLAELAVKYDMVIISP-ILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPR 202
L GP L E+A +Y++ I ++ER D +NTA +I G+V+ ++ K HIP
Sbjct: 83 LDGPEMRRLGEVAKEYNLYIAGGGVVERVKEFPDRWFNTAFIIGPSGEVVLRYHKWHIPA 142
Query: 203 ---VGD-----FNESTYYFEGN--TGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAE 252
+G F+E F G+ T PV +T+ GK+ C+ P G NG E
Sbjct: 143 SIGLGTSPHDIFDEYKEVFGGDISTLFPVIDTEIGKLGTMTCHDGCTPEVSRALGYNGVE 202
Query: 253 IVFNPSA--TVSGLSE--HLWAVEARNAAIANSYYTCAIN--RVGTESFPNEFTSG 302
++ +P A V G+S+ W R A N Y N V +P F G
Sbjct: 203 VICHPVALQEVEGVSQPWDFWMFTRRTRAHDNMAYVLGSNWGTVDYAYYPKAFCPG 258
>UniRef50_Q2QQ94 Cluster: Hydrolase, carbon-nitrogen family protein,
expressed; n=4; Magnoliophyta|Rep: Hydrolase,
carbon-nitrogen family protein, expressed - Oryza sativa
subsp. japonica (Rice)
Length = 323
Score = 56.4 bits (130), Expect = 1e-06
Identities = 68/279 (24%), Positives = 114/279 (40%), Gaps = 34/279 (12%)
Query: 96 AIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAEL 155
A + ++ AA+ V LC E F+F + AEP L GP L
Sbjct: 61 ANYATCSRLAKEAASSGVKFLCFPEV----FSFIGSKDGESIKIAEP-LDGPIMQRYCSL 115
Query: 156 AVKYDMVI-ISPILER--DDIHGDTIWNTAVVINEFGKVIGKHRKNH-----IPRVGDFN 207
A + M + + E+ DD H +NT V+I++ G++ +RK H +P +
Sbjct: 116 AKESSMWLSLGGFQEKGPDDSHQ---YNTHVLIDDSGEIRSSYRKIHLFDVDVPGNMVYK 172
Query: 208 ESTYYFEGNTGHPVFETKYGKVAINICYGRHHP-LNWLMFGINGAEIVFNPSATVSGLSE 266
ES + G+T V ++ +G++ + +CY P L + + A+++ PSA E
Sbjct: 173 ESRFTTAGDTVVAV-DSPFGRLGLTVCYDLRFPELYQCLRFKHQAQVLLVPSAFTKVTGE 231
Query: 267 HLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGS 326
W + R AI Y A + G H + YG S + P G+
Sbjct: 232 AHWEILLRARAIETQCYVIAAAQAG---------------KHNEKRESYGDSIIIDPWGT 276
Query: 327 RTPGL-SRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLD 364
L R+ G +A VDL+ ++ K + ++ D
Sbjct: 277 VIARLPDRLSTGFAVADVDLSKVEAVRTKMPISEHRKFD 315
>UniRef50_Q5KJU9 Cluster: Hydrolase, putative; n=1; Filobasidiella
neoformans|Rep: Hydrolase, putative - Cryptococcus
neoformans (Filobasidiella neoformans)
Length = 301
Score = 56.4 bits (130), Expect = 1e-06
Identities = 50/192 (26%), Positives = 78/192 (40%), Gaps = 16/192 (8%)
Query: 106 SAAAAEQVNILCLQEAWNMPFAFCT----REKQP-----WCDFAEPVLTGPSTVFLAELA 156
+AA++ + ++ L E WN P+A + EK P W E G + L E+A
Sbjct: 37 AAASSPKPQLIVLPEIWNSPYAVSSFREYSEKVPEVGSKWKSLKEGE-EGETIKALREMA 95
Query: 157 VKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH-----IPRVGDFNESTY 211
+I + D D I+NT V + G ++ H+K H IP F ES
Sbjct: 96 RSSGCWLIGGSIPERDEKTDNIYNTCTVYDPEGTLVAVHQKVHLFDIDIPGKQTFKESDT 155
Query: 212 YFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAV 271
G + F T +GK+ + ICY P ++ G + P+A + W +
Sbjct: 156 -LTGGSHLTTFTTPFGKIGLGICYDIRFPEMAMIAARQGCIAMIYPAAFNTTTGPMHWTL 214
Query: 272 EARNAAIANSYY 283
R A+ N Y
Sbjct: 215 LQRARAVDNEIY 226
>UniRef50_A2BKF1 Cluster: Predicted amidohydrolase; n=1;
Hyperthermus butylicus DSM 5456|Rep: Predicted
amidohydrolase - Hyperthermus butylicus (strain DSM 5456
/ JCM 9403)
Length = 272
Score = 56.4 bits (130), Expect = 1e-06
Identities = 53/195 (27%), Positives = 86/195 (44%), Gaps = 9/195 (4%)
Query: 99 EKVQKIISAAAAEQVNILCLQEAWNM-PFAFCTREKQPWCDFAEPVLTGPSTVFLAELAV 157
E++++++S E +I+ L E N+ P E + AE P FL E++
Sbjct: 22 ERLRRLLSRYRVE-ADIIVLPEYGNVYPAGLRAAEVRAR---AENPKDSPFIRFLEEISS 77
Query: 158 KYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNT 217
+Y VI+S LER GD +++ V++ +V +RK + ES G
Sbjct: 78 EYTAVIVSGFLERS---GDCAYSSIVMVEPGKEVQVVYRKTVLFDALGVRESKSLCRGEQ 134
Query: 218 GHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSG-LSEHLWAVEARNA 276
PV E + +V +C+ P + GAE+V P+A G L E V AR+
Sbjct: 135 PPPVLEVRGVRVGFIVCFELRFPELARSLALRGAELVAVPAAWYRGNLKEEHLLVTARSR 194
Query: 277 AIANSYYTCAINRVG 291
A+ N+ Y + G
Sbjct: 195 ALENTVYLAVASMTG 209
>UniRef50_A5FKF8 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=5; Bacteria|Rep:
Nitrilase/cyanide hydratase and apolipoprotein
N-acyltransferase - Flavobacterium johnsoniae UW101
Length = 321
Score = 56.0 bits (129), Expect = 2e-06
Identities = 41/162 (25%), Positives = 80/162 (49%), Gaps = 11/162 (6%)
Query: 101 VQKIISAAAAEQVNILCLQEAWNMPFAFC-TREKQPWCDFAEPVLTGPSTVFLAELAVKY 159
++K+ A+ E +++ E + F + ++ D AE + +G S + L E+A K
Sbjct: 25 IEKLSQKASIEGCDVISFHECSITGYTFARSLSREQMLDLAELIPSGESILKLTEIAKKN 84
Query: 160 DMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGH 219
D+VI++ + E+D+ + ++ V +++ G ++ K+RK H P + Y +
Sbjct: 85 DIVILAGLFEKDE--NNNLFKAQVCVDKNG-LVAKYRKLH-PFINP------YLTAGDRY 134
Query: 220 PVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATV 261
+FE + K I ICY + N + GA+I+F P T+
Sbjct: 135 CIFEIEGWKCGILICYDNNIIENVRATKLLGADIIFMPHVTM 176
>UniRef50_A4SSL0 Cluster: Beta-ureidopropionase; n=1; Aeromonas
salmonicida subsp. salmonicida A449|Rep:
Beta-ureidopropionase - Aeromonas salmonicida (strain
A449)
Length = 277
Score = 56.0 bits (129), Expect = 2e-06
Identities = 42/166 (25%), Positives = 73/166 (43%), Gaps = 5/166 (3%)
Query: 132 EKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKV 191
E+Q + D AE + GP LA A +Y + +++ + I +++V + G++
Sbjct: 47 ERQGYLDGAERIGEGPIQQQLAAWAKEYGIWLVAGAMPTAIPGSAHIHTSSLVFDPAGEL 106
Query: 192 IGKHRKNHIPRVGDFNESTYYFEGNTGHP-----VFETKYGKVAINICYGRHHPLNWLMF 246
G + K H+ V + Y E T P + ++ +G + ++ICY P +
Sbjct: 107 KGHYHKIHLFDVDVADNQGRYRESETFSPGQDCVLIDSPFGPLGLSICYDLRFPELYRQL 166
Query: 247 GINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGT 292
GA ++ P+A + E W R AI N Y A N+ GT
Sbjct: 167 ARAGARVLLVPAAFTAVTGEAHWEPLLRARAIENQCYVVAANQGGT 212
>UniRef50_A1IFF1 Cluster: Hydrolase, carbon-nitrogen family; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep: Hydrolase,
carbon-nitrogen family - Candidatus Desulfococcus
oleovorans Hxd3
Length = 270
Score = 56.0 bits (129), Expect = 2e-06
Identities = 50/187 (26%), Positives = 78/187 (41%), Gaps = 14/187 (7%)
Query: 105 ISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVII 164
I+ AA+ ++ L E W P F R A T ++ A ++ MVI
Sbjct: 31 IAGLAAQGADLAVLPELW--PCGFDNRHLA-----AHAAQTPRILEIVSAQAAEHSMVIA 83
Query: 165 SPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFET 224
+ E D I NT VV++ G+ G++RK H+ G E ++ +G V +T
Sbjct: 84 GSVPEAGP---DGICNTLVVMDRDGREAGRYRKIHLFSAG--GEERFFAKGKAW-AVCDT 137
Query: 225 KYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYT 284
GK+ + ICY P + ++GA V P+ +H W + AI N +
Sbjct: 138 AAGKLGLMICYDLRFPELCRVLALDGAACVIVPAQWPEARIDH-WNALLKARAIENQLFV 196
Query: 285 CAINRVG 291
NR G
Sbjct: 197 VGANRCG 203
>UniRef50_Q2LUZ0 Cluster: Carbon-nitrogen hydrolase family protein;
n=1; Syntrophus aciditrophicus SB|Rep: Carbon-nitrogen
hydrolase family protein - Syntrophus aciditrophicus
(strain SB)
Length = 268
Score = 55.6 bits (128), Expect = 2e-06
Identities = 57/254 (22%), Positives = 111/254 (43%), Gaps = 28/254 (11%)
Query: 97 IFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELA 156
+ E +Q+ S + ++L L E +N + F ++ + AE + G +T FL +A
Sbjct: 15 VAENLQQTESLINCTKADLLVLPELFNTGYLFTAHQEV--AELAEEIPGGRTTEFLCGMA 72
Query: 157 VKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFE-G 215
+ I++ + ER+ +N+AV+++ G +G +RK H+ FNE +F+ G
Sbjct: 73 RRGGSFIVAGLAEREK---GRFYNSAVLVSPRG-YLGTYRKIHL-----FNEEKLWFQPG 123
Query: 216 NTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARN 275
+ +++ ++ I IC+ P + + GA+++ + + V + A++ R
Sbjct: 124 DRAPELYDLGICRIGIMICFDWFFPEFMRILSLKGADVICHCANLVLPFCQD--AMKTR- 180
Query: 276 AAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIK 335
+ N Y NR G + DG+ F G S VT P I
Sbjct: 181 -CLENHVYAITANRTGQD-------VRDGRTL-----SFTGKSQVTGPHADVLYQAGSIG 227
Query: 336 DGLLIAQVDLNLCR 349
D + + +D++ R
Sbjct: 228 DEVAVVDIDVSRAR 241
>UniRef50_A0RYH6 Cluster: Amidohydrolase; n=1; Cenarchaeum
symbiosum|Rep: Amidohydrolase - Cenarchaeum symbiosum
Length = 269
Score = 55.6 bits (128), Expect = 2e-06
Identities = 48/195 (24%), Positives = 80/195 (41%), Gaps = 8/195 (4%)
Query: 100 KVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPV--LTGPSTVFLAELAV 157
++ K +S AAA ++ E F T Q + A + GP +A+ A
Sbjct: 21 RIVKYVSEAAAGGAGLVAFPEF----MMFYTPPGQTPAELARLAENIDGPFVKSVADAAR 76
Query: 158 KYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNT 217
Y + ++ I ER G +++T+ ++ G ++ +RK H+ F ES G+
Sbjct: 77 DYSIEVVGTIYERSPRRG-RVYDTSFLLGRDGSLLSSYRKIHLYDALGFKESAKLAPGDR 135
Query: 218 GHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLS-EHLWAVEARNA 276
+ G + + ICY P +GA ++ PSA V G + E W R
Sbjct: 136 MTVPSGSSVGSLGMLICYDLRFPEAARTLASSGAGVIVAPSAWVQGKNKEDQWITMNRAR 195
Query: 277 AIANSYYTCAINRVG 291
A+ N Y + VG
Sbjct: 196 AMENGCYLVSPAHVG 210
>UniRef50_A5TTZ3 Cluster: Possible amidohydrolase; n=1;
Fusobacterium nucleatum subsp. polymorphum ATCC
10953|Rep: Possible amidohydrolase - Fusobacterium
nucleatum subsp. polymorphum ATCC 10953
Length = 274
Score = 55.2 bits (127), Expect = 3e-06
Identities = 67/271 (24%), Positives = 116/271 (42%), Gaps = 33/271 (12%)
Query: 99 EKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWC-DFAEPVLTGPSTVFLAELAV 157
+K+ + I AA E V+I+C E + + T E Q DF + L E A
Sbjct: 28 KKIFERIEEAAKENVDIICFPELATIGYTITTDELQNLPEDFNNTFIEK-----LQEKAK 82
Query: 158 KYDMVIISPILE-RDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGN 216
+ + I+ LE + +N+ + I++ GK++ RK ++ + E T + G+
Sbjct: 83 LFKIHILVGYLESKTTKKSKDFYNSCIFIDDEGKILANARKVYLWK----KEKTKFKAGD 138
Query: 217 TGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNA 276
V +TK+GK+ I ICY + + GAEI+F PS S +E+ W ++
Sbjct: 139 K-FIVKDTKFGKIGILICYDLEFFEPARIECLKGAEIIFVPSLW-SLNAENRWHIDLAAN 196
Query: 277 AIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKD 336
++ N + N VG G S + P+GS S K+
Sbjct: 197 SLFNLLFMVGCNAVGDSC--------------------CGKSKIVEPNGSTLIEASGTKE 236
Query: 337 GLLIAQVDLNLCRQIKDKWGFTMTQRLDLYA 367
LL+A +DL +I++K + + D ++
Sbjct: 237 ELLLATIDLAKLDEIRNKIPYLSDFKSDTFS 267
>UniRef50_P55176 Cluster: UPF0012 hydrolase in pqqF 5'region; n=11;
Pseudomonas|Rep: UPF0012 hydrolase in pqqF 5'region -
Pseudomonas fluorescens
Length = 285
Score = 55.2 bits (127), Expect = 3e-06
Identities = 57/221 (25%), Positives = 93/221 (42%), Gaps = 23/221 (10%)
Query: 146 GPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGD 205
GPS +A +A I+ ER + G I+N +I+ G+ + +RK H+ GD
Sbjct: 82 GPSAQRIAAIAQAAGTAILYGYPERS-VDGQ-IYNAVQLIDAQGQRLCNYRKTHL--FGD 137
Query: 206 FNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLS 265
+ S + G P+ E K+ ICY P N + GAE++ P+A +
Sbjct: 138 LDHSMFS-AGEDDFPLVELDGWKLGFLICYDIEFPENARRLALAGAELILVPTANMIPY- 195
Query: 266 EHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDG 325
+ + V R A N Y N G H++ + G S + APDG
Sbjct: 196 DFVADVTIRARAFENQCYVAYANYCG----------------HEEQIRYCGQSSIAAPDG 239
Query: 326 SRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
SR L+ + + L+I +D L + + + +R +LY
Sbjct: 240 SRI-ALAGLDEALIIGTLDRQLMGESRALNRYLSDRRPELY 279
>UniRef50_Q8DCG5 Cluster: Predicted amidohydrolase; n=33;
Gammaproteobacteria|Rep: Predicted amidohydrolase -
Vibrio vulnificus
Length = 274
Score = 54.8 bits (126), Expect = 4e-06
Identities = 58/228 (25%), Positives = 96/228 (42%), Gaps = 25/228 (10%)
Query: 133 KQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVI 192
++ + AEP+ GP +A+LA + + ++ I G + T++V G+ +
Sbjct: 49 REDYHQHAEPLGNGPLQQAMAQLAKRLAVTLV--IGSMPIRQGHDVTTTSLVFGPNGERL 106
Query: 193 GKHRKNHIPRV------GDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMF 246
G + K H+ V G + ES + G+ V T G++ ++ICY P +
Sbjct: 107 GHYSKLHMFDVEVSDGHGHYRESDSFLAGDRSS-VVATPIGRLGLSICYDVRFPALYQTL 165
Query: 247 GINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKP 306
GA+I+ P+A + E W + R AI N + A + G S E
Sbjct: 166 RQKGADILLVPAAFTAVTGEAHWEILLRARAIENQCWVIAAAQGGMHSASRE-------- 217
Query: 307 AHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDK 354
+G S V P G L + D LL+A++DL L I+ K
Sbjct: 218 -------TWGHSMVIDPWGKVVAQLPQQGD-LLLAEIDLALSDTIRRK 257
>UniRef50_Q17CS4 Cluster: Nitrilase, putative; n=3; Culicidae|Rep:
Nitrilase, putative - Aedes aegypti (Yellowfever
mosquito)
Length = 477
Score = 54.8 bits (126), Expect = 4e-06
Identities = 37/118 (31%), Positives = 54/118 (45%), Gaps = 4/118 (3%)
Query: 178 IWNTAVVINEFGKVIGKHRKNHIPRVGD----FNESTYYFEGNTGHPVFETKYGKVAINI 233
I+NT +VI+ G+++ ++RK H+ V F ES G+ P ET G+V + I
Sbjct: 135 IYNTHIVIDNEGQLVAQYRKLHMFNVVTPEFKFRESETVRSGSELVPPIETPIGRVGLQI 194
Query: 234 CYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVG 291
CY + GAEI+ PSA W V R AI N + A ++G
Sbjct: 195 CYDVRFAEASTLLRKQGAEILTYPSAFAVSTGRAHWEVLLRARAIENQCFVIAAAQIG 252
>UniRef50_Q72HE8 Cluster: Beta-ureidopropionase; n=2; Thermus
thermophilus|Rep: Beta-ureidopropionase - Thermus
thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 292
Score = 54.4 bits (125), Expect = 5e-06
Identities = 37/138 (26%), Positives = 65/138 (47%), Gaps = 11/138 (7%)
Query: 163 IISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVF 222
++ ERD+ +N+A + +V+ HRK +P G F+E Y G F
Sbjct: 85 VVVGFYERDE---GAYYNSAAYLELPHRVVHVHRKVFLPTYGVFDEERYLARGRRVE-AF 140
Query: 223 ETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVS-----GLSEHL--WAVEARN 275
T++G+ A+ IC H + + ++GAE+++ PSA+ + G E++ W A+
Sbjct: 141 RTRFGRAALLICEDFWHSITATIAALDGAEVIYVPSASPARGFQGGYPENVARWRTLAQA 200
Query: 276 AAIANSYYTCAINRVGTE 293
A + Y + VG E
Sbjct: 201 VAAEHGLYVVVASLVGFE 218
>UniRef50_Q1PXD4 Cluster: Similar to N-carbamoyl-D-amino acid
hydrolase; n=1; Candidatus Kuenenia stuttgartiensis|Rep:
Similar to N-carbamoyl-D-amino acid hydrolase -
Candidatus Kuenenia stuttgartiensis
Length = 277
Score = 54.0 bits (124), Expect = 6e-06
Identities = 45/171 (26%), Positives = 76/171 (44%), Gaps = 7/171 (4%)
Query: 126 FAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVI 185
F+F +E++ FAE TG FL + ++K+ + II + + NT +V
Sbjct: 45 FSFIGQEREN-ITFAEERETGEIVHFLKKFSMKHSVAIIGGSVPLRSSSKAKVTNTCLVF 103
Query: 186 NEFGKVIGKHRKNHIPRVGDFNESTYYFEGNT---GHPVFETK-YGKV-AINICYGRHHP 240
++ G +IG + K H+ ++ T Y E + G + K +G + + ICY P
Sbjct: 104 DQSGVIIGSYDKIHLFDF-HLDDKTVYRESHYVKHGKHIETVKLFGHIMGLCICYDLRFP 162
Query: 241 LNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVG 291
+ + G E++F PSA + W + R AI N Y A + G
Sbjct: 163 ELFRKLMLRGMEVLFAPSAFTMETGKDHWEILLRARAIENQCYVVAPAQYG 213
>UniRef50_A3ZLM3 Cluster: Putative nitrilase; n=1; Blastopirellula
marina DSM 3645|Rep: Putative nitrilase -
Blastopirellula marina DSM 3645
Length = 258
Score = 54.0 bits (124), Expect = 6e-06
Identities = 47/199 (23%), Positives = 92/199 (46%), Gaps = 15/199 (7%)
Query: 99 EKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVK 158
+ +++I+ AA ++ L E +N + + AE + +GP+ V + + A+K
Sbjct: 12 QTAERLIAQAAERGAQLVVLPELFNY-----LGRLENLVEHAETI-SGPTAVRMRKAALK 65
Query: 159 YDMVIIS-PILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH-----IPRVGDFNESTYY 212
+ + +++ ER + ++NT+++ + GK IG +RK H +P V +ES++
Sbjct: 66 HQIYLVAGSFAERSETES-RVFNTSLIFDPLGKQIGVYRKIHLFDIDLPDV-QVHESSFV 123
Query: 213 FEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVE 272
G+ + +T G VA ICY P + + + P+A + W +
Sbjct: 124 APGSE-VSLCQTALGGVAQAICYDLRFPEIVRSYDLEKVACLALPAAFTAKTGAAHWQIL 182
Query: 273 ARNAAIANSYYTCAINRVG 291
R+ AI N + A N+ G
Sbjct: 183 VRSRAIENQLFLIAANQYG 201
>UniRef50_UPI0000D55F17 Cluster: PREDICTED: similar to CG7067-PA;
n=2; Coelomata|Rep: PREDICTED: similar to CG7067-PA -
Tribolium castaneum
Length = 445
Score = 53.6 bits (123), Expect = 8e-06
Identities = 69/278 (24%), Positives = 114/278 (41%), Gaps = 33/278 (11%)
Query: 101 VQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYD 160
V++++S AA +Q I+ L EA + + K FAEP L G LA K
Sbjct: 26 VKQLVSEAAQKQAKIVFLPEASD----YIAANKNEAKAFAEP-LNGTLMNEYRNLA-KTR 79
Query: 161 MVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH-----IPRVG-DFNESTYYFE 214
V +S + ++ I+NT V+I++ G++ ++K H IP + + ES
Sbjct: 80 KVWLSVGGFHELVNEHQIFNTHVLIDDEGEIKSVYKKLHLFDVSIPELNVNLRESDLNEA 139
Query: 215 GNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEAR 274
G P T G +A+ ICY P ++ GA I+ PSA W R
Sbjct: 140 GRHLVPPVMTPAGPLALAICYDLRFPELSIIQRKQGANILTYPSAFTKATGALHWETLLR 199
Query: 275 NAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRI 334
+ AI Y A + G H + YG + + P G +
Sbjct: 200 SRAIETQCYVIAAAQYG---------------KHNEKRTSYGQALIVDPQGKIIAECPKY 244
Query: 335 KDG------LLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
++G + IA++D NL ++++ + +R D+Y
Sbjct: 245 REGHETNQSIAIAEIDSNLIQKVRTEMPVFQHRRSDIY 282
>UniRef50_Q8KCC8 Cluster: Carbon-nitrogen hydrolase family protein;
n=10; Chlorobiaceae|Rep: Carbon-nitrogen hydrolase
family protein - Chlorobium tepidum
Length = 286
Score = 53.6 bits (123), Expect = 8e-06
Identities = 53/220 (24%), Positives = 90/220 (40%), Gaps = 29/220 (13%)
Query: 160 DMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGH 219
D+ I +E D +G ++N+A + + G HRK ++P G F E Y+ G
Sbjct: 77 DICIFCGGIELSDDYG--VYNSAFMFED-GAGRSVHRKIYLPTYGMFEELRYFSAGRQIE 133
Query: 220 PVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVF---------NPSATVSGLSEHLWA 270
V + GKV + IC H + GA+++ +P V + W
Sbjct: 134 TVTSRRIGKVGVAICEDFWHMSVPYLLAHQGAKLLLVLMSSPLRLSPGQGVPAIVTQ-WQ 192
Query: 271 VEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPG 330
A +A S Y +NRVG E + FT ++G+S VT PDGS
Sbjct: 193 TIASTSAFLLSCYVACVNRVGNE---DSFT-------------YWGNSAVTTPDGSIAAS 236
Query: 331 LSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLYAQSL 370
+ A +D ++ ++++ + + + L+A L
Sbjct: 237 APMFSEHSFDATIDYSVVKRVRLQSSHFLDEDTKLFASQL 276
>UniRef50_Q6N4F1 Cluster: Possible amidohydrolase; n=2;
Rhodopseudomonas palustris|Rep: Possible amidohydrolase
- Rhodopseudomonas palustris
Length = 557
Score = 53.6 bits (123), Expect = 8e-06
Identities = 46/192 (23%), Positives = 85/192 (44%), Gaps = 12/192 (6%)
Query: 103 KIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWC-DFAEPVLTGPSTVFLAELAVKYDM 161
+ + AA + ++ E + + F + E C + AE + GP LA L+ K+ +
Sbjct: 29 RYVEDAARQGAELIVFPECMDTGYLFDSPEH---CRELAETLTDGPFVKALAALSRKHGV 85
Query: 162 VIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPV 221
I S I E D + I+NT ++ + G+V + K + ++ ++ G G PV
Sbjct: 86 YIASGITEWDPAK-EKIFNTGIMFDRKGEVACHYHKQFLAT----HDQNWFAFGERGCPV 140
Query: 222 FETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANS 281
ET GK+ + IC+ P + + GAE++ + + + +W AR + N
Sbjct: 141 VETDLGKIGLLICFDGRIPEIFRAMTMQGAEVIVDMANFFAMDQADMWG-PAR--SYENG 197
Query: 282 YYTCAINRVGTE 293
+ A + G E
Sbjct: 198 VWLVAATKAGYE 209
Score = 50.8 bits (116), Expect = 6e-05
Identities = 33/120 (27%), Positives = 57/120 (47%), Gaps = 8/120 (6%)
Query: 152 LAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTY 211
+A+++ +Y +I +PI+ER ++ T V+I GK IG++RK H+ E
Sbjct: 360 VAKISARYGCLIAAPIVERA---AAGLYVTTVLIGSDGKEIGRYRKTHLTA-----EERK 411
Query: 212 YFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAV 271
+ +PVF+T +G++ + Y P I A+I+ P+A L AV
Sbjct: 412 WAVAGFDYPVFDTPFGRIGVMSGYDAVFPETSRCLAIGAADIILWPAALREPFERELLAV 471
>UniRef50_A0BR54 Cluster: Chromosome undetermined scaffold_122,
whole genome shotgun sequence; n=2;
Oligohymenophorea|Rep: Chromosome undetermined
scaffold_122, whole genome shotgun sequence - Paramecium
tetraurelia
Length = 281
Score = 53.6 bits (123), Expect = 8e-06
Identities = 62/285 (21%), Positives = 119/285 (41%), Gaps = 27/285 (9%)
Query: 88 NPITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGP 147
N IT + V+ I AA + + L E +N + + DF + TG
Sbjct: 12 NAITATKTQTLALVKDQIKEAAIQGSKVCILGECFNSYYVKAQLQNNAE-DFGK---TGE 67
Query: 148 STVF--LAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGD 205
++E++ ++ ++II I E+ GD ++NTA N G+++ +RK H+ +
Sbjct: 68 RQTLDLISEISKQFGIMIIGSIPEKS---GDKMYNTAFCFNN-GQLLVTYRKTHLFDIDI 123
Query: 206 FNESTYY----FEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATV 261
+ TY F + + +T+YGK I ICY P + G + P +
Sbjct: 124 PGKITYKESLTFSAGDNYKIVDTEYGKFGIGICYDIRFPELAQIMREKGCHFLVYPGSFN 183
Query: 262 SGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVT 321
W + + A+ Y C + V + + G+ + +K +GH S +
Sbjct: 184 LTTGPLHWELLLKARAVD---YQCYVAGVSSARY-----MGNDESIYKAWGH----STLL 231
Query: 322 APDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
P ++ ++I++VDL+ Q++ + + +R D+Y
Sbjct: 232 DP-MAKVLATCEHDPSVIISEVDLDYLEQVRQQIPVSQQRRNDIY 275
>UniRef50_O76463 Cluster: Nitrilase and fragile histidine triad
fusion protein NitFhit [Includes:
Bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29)
(Diadenosine 5',5'''-P1,P3-triphosphate hydrolase)
(Dinucleosidetriphosphatase) (AP3A hydrolase) (AP3Aase);
Nitrilase homolog (EC 3.5.-.-)]; n=4; Bilateria|Rep:
Nitrilase and fragile histidine triad fusion protein
NitFhit [Includes: Bis(5'-adenosyl)-triphosphatase (EC
3.6.1.29) (Diadenosine 5',5'''-P1,P3-triphosphate
hydrolase) (Dinucleosidetriphosphatase) (AP3A hydrolase)
(AP3Aase); Nitrilase homolog (EC 3.5.-.-)] -
Caenorhabditis elegans
Length = 440
Score = 53.6 bits (123), Expect = 8e-06
Identities = 57/225 (25%), Positives = 89/225 (39%), Gaps = 22/225 (9%)
Query: 154 ELAVKYDMVI-ISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH-----IPRVGDFN 207
ELA K+++ + + + +D WNT ++I+ G ++ K H IP
Sbjct: 83 ELARKHNIWLSLGGLHHKDPSDAAHPWNTHLIIDSDGVTRAEYNKLHLFDLEIPGKVRLM 142
Query: 208 ESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEH 267
ES + G P +T G++ ++ICY P L GA+++ PSA
Sbjct: 143 ESEFSKAGTEMIPPVDTPIGRLGLSICYDVRFPELSLWNRKRGAQLLSFPSAFTLNTGLA 202
Query: 268 LWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSR 327
W R AI N Y A + G AH YG S V P G+
Sbjct: 203 HWETLLRARAIENQCYVVAAAQTG---------------AHNPKRQSYGHSMVVDPWGAV 247
Query: 328 TPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLYAQSLNE 372
S D + A++DL+ +++ +R DLY +NE
Sbjct: 248 VAQCSERVD-MCFAEIDLSYVDTLREMQPVFSHRRSDLYTLHINE 291
>UniRef50_A0L7H1 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=2;
Proteobacteria|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Magnetococcus sp.
(strain MC-1)
Length = 275
Score = 53.2 bits (122), Expect = 1e-05
Identities = 44/196 (22%), Positives = 86/196 (43%), Gaps = 8/196 (4%)
Query: 100 KVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKY 159
+ ++++ AA +L L E N F F EK+ +P GPS + A ++
Sbjct: 26 RAEQLLEEAATAGAKLLVLPE--NFSF-FGADEKEKLAHQEDPQ-HGPSLRMVQAFAQRH 81
Query: 160 DMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRV----GDFNESTYYFEG 215
+++ + D + N++ V+N+ G+V+ ++ K H+ V G+ +
Sbjct: 82 GAWVVAGSIPTDVGESQRVANSSFVVNDQGQVVARYDKIHLFDVTLNGGEGYRESDMIRA 141
Query: 216 NTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARN 275
+ V ++ +G++ ++ICY P + GAEI P+A + W + R
Sbjct: 142 GSQPVVVDSPFGRIGLSICYDLRFPELYRALTDAGAEIFTVPAAFTLTTGQVHWELLLRA 201
Query: 276 AAIANSYYTCAINRVG 291
A+ N + A N+ G
Sbjct: 202 RAVENFCHLLAPNQWG 217
>UniRef50_Q3IW15 Cluster: Predicted amidohydrolase; n=2; Rhodobacter
sphaeroides|Rep: Predicted amidohydrolase - Rhodobacter
sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 /
DSM158)
Length = 280
Score = 52.8 bits (121), Expect = 1e-05
Identities = 66/227 (29%), Positives = 96/227 (42%), Gaps = 38/227 (16%)
Query: 139 FAEPVLTGPS---TVFLAELAVKYDMVIISPIL---ERDDIH---------GDTIWNTAV 183
F E LTG S L + AV + ++PIL DIH G NTA
Sbjct: 39 FPECFLTGGSFDDRAALLQAAVDIERGDLAPILLAAREADIHVVVGFYQKSGPQALNTAA 98
Query: 184 VINEFGKVIGKHRKNHIP-RVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLN 242
+I G +IG H K H+P +GD EG + VF+T G++ + ICY P
Sbjct: 99 LIGPEG-IIGLHHKMHLPFMIGDRFADIPQIEGPS---VFDTAIGRIGLAICYEIRFPEV 154
Query: 243 WLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSG 302
+ GAE+V P+A + L + +R A N Y + NR+ +
Sbjct: 155 IRTLALEGAELVVLPAAWPEA-ARILPDLFSRVRAAENFVYFLSSNRIDVD--------- 204
Query: 303 DGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCR 349
DG F GSS+V PDG+ + +++G+ +DL R
Sbjct: 205 DGMA-------FMGSSHVIGPDGNEIFN-AGMQEGIFTVDIDLARAR 243
>UniRef50_Q2NTW0 Cluster: Putative uncharacterized protein; n=2;
Sodalis glossinidius str. 'morsitans'|Rep: Putative
uncharacterized protein - Sodalis glossinidius (strain
morsitans)
Length = 271
Score = 52.8 bits (121), Expect = 1e-05
Identities = 51/221 (23%), Positives = 92/221 (41%), Gaps = 22/221 (9%)
Query: 152 LAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTY 211
L++LA + + II+ +ER + G + V E + RK H+ GD E +
Sbjct: 72 LSQLAGELGLHIIAGFVERGERTGQVYNSAGVWAPEGQSWLHAQRKIHL--WGD--EKKW 127
Query: 212 YFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAV 271
+ EG + + T GK+ + +CY P +F + +I+F A S ++W +
Sbjct: 128 FSEGEQ-YEIIATPLGKIGVMVCYDLGFPEVARIFALRQVDILF-VIAAWSEAEAYIWDI 185
Query: 272 EARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGL 331
A+ N + A+NR G E GD + +G S + APDG
Sbjct: 186 NCAARALENGVFLVAVNRWGEE--------GDLR--------LFGGSQIMAPDGQCVVRA 229
Query: 332 SRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLYAQSLNE 372
+ + L+ +DL+ ++ + ++ Y + NE
Sbjct: 230 TDKGEALVYGNIDLSQLANVRMTLPYRKDVKIASYKEHYNE 270
>UniRef50_A4BQN0 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Nitrococcus
mobilis Nb-231|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Nitrococcus mobilis
Nb-231
Length = 287
Score = 52.8 bits (121), Expect = 1e-05
Identities = 46/200 (23%), Positives = 81/200 (40%), Gaps = 8/200 (4%)
Query: 96 AIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAEL 155
A E ++I+ A A +++ L E FAF R++ AEP GP FLAE
Sbjct: 21 ANLESADRLIAEAVAGGADLVALPEN----FAFVGRDETGKLAIAEPDDGGPIQSFLAER 76
Query: 156 AVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYY--- 212
A ++ + ++ + +V G+ ++ K H+ V + Y
Sbjct: 77 ARRHGIFLVGGTIPLHTSDQRRARAACLVYGPSGERCARYDKIHLFDVAVSADERYCESE 136
Query: 213 -FEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAV 271
+ +F+T + +V + +CY P + GAE++ PSA + W +
Sbjct: 137 TLQAGNNAVIFDTPFARVGLAVCYDLRFPELFRELVARGAELLVVPSAFTALTGAAHWEL 196
Query: 272 EARNAAIANSYYTCAINRVG 291
R A+ N Y A ++ G
Sbjct: 197 LVRTRAVENLCYLVAPDQGG 216
>UniRef50_A3LZY2 Cluster: Aliphatic nitrilase; n=1; Pichia
stipitis|Rep: Aliphatic nitrilase - Pichia stipitis
(Yeast)
Length = 323
Score = 52.8 bits (121), Expect = 1e-05
Identities = 66/278 (23%), Positives = 115/278 (41%), Gaps = 24/278 (8%)
Query: 89 PITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCD---FAEPV-- 143
P+ + A EKV +S AA++ N++ E + F K P + F + V
Sbjct: 15 PVMMNKEATMEKVFNGVSEAASKGANLIVFPETYVSAFPLWGACKAPIDNHHLFKQLVES 74
Query: 144 ---LTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHI 200
+ GP L L + +V++ ER + +WN+ V+I+E G IG H + +
Sbjct: 75 SIYIDGPEISSLQSLCKELSVVVLLGFNERSRVSVGCLWNSYVLIDENG-TIGAHHRKLV 133
Query: 201 PRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEI---VFNP 257
P F + ++ +G V ++KYGK+ IC + L G +I ++ P
Sbjct: 134 PTF--FEKLSWANGDGSGLNVIDSKYGKIGCLICGENTNSLARFTLLSQGEQIHISIWPP 191
Query: 258 SATVSGLSEHLWAVEARNAAIANSYYTCAINR---VGTESFPN----EFTSGDGKPAHKD 310
+A + SE + + A C + V + SF + +F D P++
Sbjct: 192 AADMHRPSEETKSFDNITANKIRCGAQCIEGKCFGVLSSSFVDQAMLDFLIKD-DPSNAS 250
Query: 311 F--GHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLN 346
F G + +P G+ R ++G+ A DLN
Sbjct: 251 FYNNMSQGITCFLSPSGNEIGDSLRFQEGIAYADFDLN 288
>UniRef50_A3CTE8 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Methanoculleus
marisnigri JR1|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Methanoculleus
marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
Length = 265
Score = 52.8 bits (121), Expect = 1e-05
Identities = 51/198 (25%), Positives = 78/198 (39%), Gaps = 12/198 (6%)
Query: 99 EKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVK 158
E ++ AAA +++C E F K P EP L GP T A +A +
Sbjct: 21 EAAGRMAGEAAAAGASLICFPEQ----FVTGWSPKVP-PGSGEP-LDGPLTAAFARIAEE 74
Query: 159 YDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTG 218
+ + I+E + NT VV++E G+++ + K H+ E YY G+
Sbjct: 75 NGIAVAGSIVEAGLENRPK--NTTVVLDEDGELLAAYAKIHL--FSPEGEDRYYTAGDR- 129
Query: 219 HPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAI 278
F K I +CY P + ++ I G E + P+A H W A+
Sbjct: 130 IATFTVDGVKFGIAVCYDLRFPELFRIYAIAGVECMLVPAAWPCSRLSH-WETLLPARAL 188
Query: 279 ANSYYTCAINRVGTESFP 296
N YY +N G P
Sbjct: 189 ENRYYVTGVNTAGRPGAP 206
>UniRef50_P58054 Cluster: UPF0012 hydrolase ybeM; n=33;
Proteobacteria|Rep: UPF0012 hydrolase ybeM - Escherichia
coli O157:H7
Length = 262
Score = 52.8 bits (121), Expect = 1e-05
Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 2/117 (1%)
Query: 179 WNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRH 238
WN V + + G ++ ++ K H+ ES GN P+ E + KV + CY
Sbjct: 93 WNMLVAL-QAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLR 151
Query: 239 HPLNWLMFGINGAEIVFNPSATVSG-LSEHLWAVEARNAAIANSYYTCAINRVGTES 294
P L + GAEI+ P+A V G L EH W+ A+ + Y A G ++
Sbjct: 152 FPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN 208
>UniRef50_Q1F028 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Clostridium
oremlandii OhILAs|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Clostridium
oremlandii OhILAs
Length = 261
Score = 52.4 bits (120), Expect = 2e-05
Identities = 51/195 (26%), Positives = 85/195 (43%), Gaps = 13/195 (6%)
Query: 98 FEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFL-AELA 156
F+K +++I AA E + + L E W+ F F + +CD G T L ++L+
Sbjct: 19 FKKAEELIRLAAKENPDTIALPETWSTGF-FPKENIKEFCD-----QNGNRTKRLFSKLS 72
Query: 157 VKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGN 216
+ ++ II+ + + D I+NT+ + N+ G+ I ++ K H+ + YFE
Sbjct: 73 KELNVNIIAGSVINE--KQDGIYNTSYIFNKQGECIAEYDKTHL---FSYMGEDQYFEKG 127
Query: 217 TGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNA 276
+G VFE K I ICY + +I+F A L H W +
Sbjct: 128 SGITVFELDGIKCGIVICYDIRFVELVRTLALQEIKILF-VVAQWPMLRIHHWQILNEAR 186
Query: 277 AIANSYYTCAINRVG 291
AI N + +N G
Sbjct: 187 AIENQIFVACVNSCG 201
>UniRef50_A3EVA0 Cluster: NAD synthase; n=4; Bacteria|Rep: NAD
synthase - Leptospirillum sp. Group II UBA
Length = 592
Score = 52.4 bits (120), Expect = 2e-05
Identities = 51/173 (29%), Positives = 80/173 (46%), Gaps = 19/173 (10%)
Query: 176 DTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICY 235
D I+N A V++ GK+ G +RK ++P G F+E+ Y+ EG PV E + ++ INIC
Sbjct: 90 DDIYNAAAVLHG-GKLHGIYRKQYLPNYGVFDENRYFQEG-VESPVLEYRSARLGINICE 147
Query: 236 GRHHPLN--WLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTE 293
+P + + AE + N SA+ H E R N T A++
Sbjct: 148 DIWYPKGPLYTQTLMGDAECILNLSAS----PFHAGKREVRE----NMLCTRAVDSACYI 199
Query: 294 SFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLN 346
++ N G +D F G S V +PDG ++ LLI ++DL+
Sbjct: 200 AYVN-MVGG------QDELVFDGQSLVISPDGEIESRGKAFQEDLLITEIDLD 245
>UniRef50_Q9LE50 Cluster: Nitrilase 1 like protein; n=2; Arabidopsis
thaliana|Rep: Nitrilase 1 like protein - Arabidopsis
thaliana (Mouse-ear cress)
Length = 316
Score = 52.4 bits (120), Expect = 2e-05
Identities = 61/266 (22%), Positives = 107/266 (40%), Gaps = 33/266 (12%)
Query: 98 FEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAV 157
F +++ AA ++C E F+F ++ AEP L GP LA
Sbjct: 54 FATCSRLVQEAALAGAKLICFPEN----FSFVGDKEGESVKIAEP-LDGPVMERYCSLAR 108
Query: 158 KYDMVI-ISPILER-DDIHGDTIWNTAVVINEFGKVIGKHRKNH-----IPRVGDFNEST 210
++ + + ER DD H + NT VVI++ G + ++K H +P + ES+
Sbjct: 109 DSNIWLSLGGFQERFDDTH---LCNTHVVIDDAGMIRDTYQKMHLFDVDVPGGSSYKESS 165
Query: 211 YYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGING-AEIVFNPSATVSGLSEHLW 269
+ G V ++ G++ + +CY P + A+++ PSA E W
Sbjct: 166 FTVPGTKIVSV-DSPVGRLGLTVCYDLRFPKIYQQLRFEQKAQVLLVPSAFTKVTGEAHW 224
Query: 270 AVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTP 329
+ R AI Y A + G H + YG + + P G+
Sbjct: 225 EILLRARAIETQCYVIAAAQAG---------------KHNEKRESYGDTLIIDPWGTVVG 269
Query: 330 GL-SRIKDGLLIAQVDLNLCRQIKDK 354
L R+ G+++A +D +L ++ K
Sbjct: 270 RLPDRVSTGIVVADIDFSLIDSVRTK 295
>UniRef50_Q47VH0 Cluster: Hydrolase, carbon-nitrogen family; n=1;
Colwellia psychrerythraea 34H|Rep: Hydrolase,
carbon-nitrogen family - Colwellia psychrerythraea
(strain 34H / ATCC BAA-681) (Vibriopsychroerythus)
Length = 273
Score = 52.0 bits (119), Expect = 3e-05
Identities = 44/198 (22%), Positives = 84/198 (42%), Gaps = 7/198 (3%)
Query: 100 KVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVF-LAELAVK 158
K+ +++S A Q ++ L F +++ + D A TG L ELA K
Sbjct: 21 KIAELLSKITASQEDVQHLVVLPECCLYFGSKDSEQ-LDLAIASATGNDLCLALGELAKK 79
Query: 159 YDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHI--PRVGDFNES---TYYF 213
+ + +++ + N++ V N G++IG++ K H+ V D +S + Y
Sbjct: 80 FKVYLVAGTIPILSTSSTKFTNSSCVFNPEGELIGQYDKIHLFDVNVSDSTKSYCESRYT 139
Query: 214 EGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEA 273
+ + T++ + +++C+ P + I GA+I+ PSA + W
Sbjct: 140 QAGKEISMVNTEFANIGLSVCFDLRFPNLFQQLSIAGADIITVPSAFTRVTGKAHWQTLL 199
Query: 274 RNAAIANSYYTCAINRVG 291
+ AI N Y A + G
Sbjct: 200 QARAIENQVYIVAAGQEG 217
>UniRef50_A4WA35 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=12; Bacteria|Rep:
Nitrilase/cyanide hydratase and apolipoprotein
N-acyltransferase - Enterobacter sp. 638
Length = 326
Score = 52.0 bits (119), Expect = 3e-05
Identities = 49/166 (29%), Positives = 71/166 (42%), Gaps = 20/166 (12%)
Query: 101 VQKIISAAAAEQVNIL-----CLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAEL 155
++K I AA EQVNIL C+ W++P AEP+ PS + L
Sbjct: 28 IEKFIEQAALEQVNILVFPEMCITGYWHVPKLTAAEVSA----LAEPIAESPSLTLIRSL 83
Query: 156 AVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEG 215
A+K+ M+I ++ER D ++N V G + HRK H F
Sbjct: 84 AIKHQMLIGVGLIERAD--DGRLYNAYVACMPDG-TMHTHRKLHA-----FEHPA--ISS 133
Query: 216 NTGHPVFETKYG-KVAINICYGRHHPLNWLMFGINGAEIVFNPSAT 260
VF+T +G KV I IC+ + N + GA+I+ P T
Sbjct: 134 GDRFTVFDTPWGVKVGILICWDNNLVENVRATALLGADILLAPHQT 179
>UniRef50_A0LH50 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 260
Score = 51.6 bits (118), Expect = 3e-05
Identities = 38/138 (27%), Positives = 66/138 (47%), Gaps = 7/138 (5%)
Query: 156 AVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEG 215
A ++ MV++ + E D I+NT+ VI+ G++ G +RK H+ + +E ++ G
Sbjct: 73 ARRHGMVLVGSLPESVD---GRIYNTSYVIDANGEIAGSYRKVHLFSL--HHEDLHFGRG 127
Query: 216 NTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARN 275
T V T+ G++ + ICY P ++GA I+ S +H W++ R
Sbjct: 128 ETS-LVCSTEAGELGVMICYDLRFPELGRKLALDGARIMCVSSHWPDIRIDH-WSLLLRA 185
Query: 276 AAIANSYYTCAINRVGTE 293
A+ N + N GTE
Sbjct: 186 RAVENQLFVIGCNGCGTE 203
>UniRef50_A5D6C3 Cluster: Putative uncharacterized protein; n=1;
Pelotomaculum thermopropionicum SI|Rep: Putative
uncharacterized protein - Pelotomaculum
thermopropionicum SI
Length = 256
Score = 51.2 bits (117), Expect = 4e-05
Identities = 45/157 (28%), Positives = 67/157 (42%), Gaps = 14/157 (8%)
Query: 144 LTGPSTVFLAELAVKYDMVIISPILERDD--IHGDTIWNTAVVINEFGKVIGKHRKNHIP 201
+ G T LAE A +Y + I LERD I +NT +I GK+I K+RK +
Sbjct: 86 IPGEETERLAEKAKEYQIYIAGCALERDKDWIDDGYFFNTHFIIGPDGKIIHKYRKITVA 145
Query: 202 RVGDFNESTY--YFEGNTGH--------PVFETKYGKVAINICYGRHHPLNWLMFGINGA 251
+ S + Y + H PV +T+ GK+ C H P G+ GA
Sbjct: 146 THYELAVSPHDVYDKFVAMHGDDLSVFLPVTDTEIGKIGTITCMDGHFPETARALGVQGA 205
Query: 252 EIVFNPSATVSGLS--EHLWAVEARNAAIANSYYTCA 286
E++ +P +S + +W + R A N Y A
Sbjct: 206 EVILHPLLVEPMMSPPQEIWQMMNRMRAWENVCYVIA 242
>UniRef50_A4ALG5 Cluster: Putative hydrolase; n=2; Actinobacteria
(class)|Rep: Putative hydrolase - marine actinobacterium
PHSC20C1
Length = 271
Score = 51.2 bits (117), Expect = 4e-05
Identities = 45/153 (29%), Positives = 62/153 (40%), Gaps = 4/153 (2%)
Query: 136 WCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKH 195
W AEP L GP L LA + + + + +LE D NT V I G V+ +
Sbjct: 57 WLAAAEP-LDGPFVQALTSLAQRLRIHVAAGMLESAD-EEKRFSNTLVAIAPTGAVVATY 114
Query: 196 RKNHIPRVGDFNESTYYFEGNTGHPVFETKYG-KVAINICYGRHHPLNWLMFGINGAEIV 254
RK H+ ES + G+ G P T G V + CY P GA ++
Sbjct: 115 RKQHLYDAFGQRESDWVIPGSIGAPETFTWEGFTVGLQTCYDIRFPEVSRRLVDAGANLI 174
Query: 255 FNPSATVSG-LSEHLWAVEARNAAIANSYYTCA 286
P+ V G L E+ W AI N+ + A
Sbjct: 175 VVPAEWVRGPLKEYHWRTLLTARAIENTIFVAA 207
>UniRef50_P47016 Cluster: Probable hydrolase NIT2; n=6;
Saccharomycetales|Rep: Probable hydrolase NIT2 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 307
Score = 51.2 bits (117), Expect = 4e-05
Identities = 54/212 (25%), Positives = 84/212 (39%), Gaps = 11/212 (5%)
Query: 166 PILERDDIHG-DTIWNTAVVINEFGKVIGKHRKNH-----IPRVGDFNESTYYFEGNTGH 219
P E+D + G D + N + I+ GK++ +++K H +P ES G
Sbjct: 95 PPSEQDLLEGNDRVRNVLLYIDHEGKILQEYQKLHLFDVDVPNGPILKESKSVQPGKAIP 154
Query: 220 PVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIA 279
+ E+ GK+ ICY P L GAEI+ PSA E W + R A+
Sbjct: 155 DIIESPLGKLGSAICYDIRFPEFSLKLRSMGAEILCFPSAFTIKTGEAHWELLGRARAVD 214
Query: 280 NSYYTCAINRVGTESFPN---EFTSGDGKPAHKDFGHFYGSSYVTAPDGS--RTPGLSRI 334
Y +VG + E S +G S V P G S +
Sbjct: 215 TQCYVLMPGQVGMHDLSDPEWEKQSHMSALEKSSRRESWGHSMVIDPWGKIIAHADPSTV 274
Query: 335 KDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
L++A +D L ++I++K +R DL+
Sbjct: 275 GPQLILADLDRELLQEIRNKMPLWNQRRDDLF 306
>UniRef50_A3HXT3 Cluster: Putative nitrilase; n=1; Algoriphagus sp.
PR1|Rep: Putative nitrilase - Algoriphagus sp. PR1
Length = 305
Score = 50.8 bits (116), Expect = 6e-05
Identities = 53/202 (26%), Positives = 90/202 (44%), Gaps = 13/202 (6%)
Query: 152 LAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTY 211
L +L + ++ ++ + ER HG +++ + + I+ G ++G HRK I G E
Sbjct: 88 LEKLCHQLNIYLVCGVTERMKQHG-SLYCSMIYISPKG-LLGVHRK--IKPTGI--ERLV 141
Query: 212 YFEGNTGHPV-FETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWA 270
+ E + V F+TK GK+ IC+ + PL + G EI P+A + W
Sbjct: 142 WAEASGDSLVTFDTKIGKLGGLICWENYMPLARMAMYSQGVEIYIAPTAD----ARESWV 197
Query: 271 VEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPG 330
R+ AI + A N+ T+S D + +DF G + + +P G G
Sbjct: 198 DTMRHIAIEGRCFVLACNQYFTKSMYPHRLQKDMEEVEEDF--CKGGTVIFSPLGELIAG 255
Query: 331 LSRIKDGLLIAQVDLNLCRQIK 352
+ G L ++DLNL + K
Sbjct: 256 PLYGEAGALSMEIDLNLITKSK 277
>UniRef50_A1SE99 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=4;
Actinomycetales|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Nocardioides sp.
(strain BAA-499 / JS614)
Length = 280
Score = 50.8 bits (116), Expect = 6e-05
Identities = 61/227 (26%), Positives = 93/227 (40%), Gaps = 30/227 (13%)
Query: 136 WCDFAEPVLTGPSTVFLAELAVKYDMVI-ISPILERDDIHGDT------IWNTAVVINEF 188
W AE ++ GP+ +A +A + + + I+ER + D +WNT+V+I+
Sbjct: 63 WRATAE-LMNGPTIAQMASVAREVGVWLHAGSIIERAEDGADRGAERRGLWNTSVLISPQ 121
Query: 189 GKVIGKHRKNHIPRVGDFNESTYYFEGN---TGHPVFETKYGKVAINICYGRHHPLNWLM 245
G V +RK H GD E G V +T +V + CY P +
Sbjct: 122 GTVHKTYRKIHRFGFGD-GEPRVLEAGTDLAVAELVHDTGASRVGMATCYDLRFPELFRR 180
Query: 246 FGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGK 305
G GA+++ P+A EH W + R A+ N + N GT S
Sbjct: 181 LGDLGADVIVLPAAWPMRRVEH-WRLLGRARALENQAWVLQCNTAGTHS----------- 228
Query: 306 PAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIK 352
D G G S V AP G L +D +L+ +DLNL ++
Sbjct: 229 --GLDMG---GHSQVVAPTGEVVAELGSDED-VLLTDIDLNLVASVR 269
>UniRef50_A0U0W3 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=4; Burkholderia
cepacia complex|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Burkholderia
cenocepacia MC0-3
Length = 275
Score = 50.8 bits (116), Expect = 6e-05
Identities = 41/153 (26%), Positives = 68/153 (44%), Gaps = 12/153 (7%)
Query: 140 AEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH 199
AEP L GPS + A + ++ + E+DD +NTA++++EFG++ ++RK+H
Sbjct: 59 AEP-LDGPSVSAIRAAARDAHVAVVIGVAEQDD---GRYFNTAILVDEFGELRLRYRKSH 114
Query: 200 IPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSA 259
+ + FE V E + KV + IC+ P GAE++ P
Sbjct: 115 L-----YESDVGVFEAGGTFDVCEWRGVKVGMLICFDLEFPETARALARAGAELIVIPDG 169
Query: 260 TVSGLSE-HLWAVEARNAAIANSYYTCAINRVG 291
+ H + R A+ N + NRVG
Sbjct: 170 MMQPHGHVHRKMIPVR--ALENQVFVAMANRVG 200
>UniRef50_Q1MYM0 Cluster: Predicted amidohydrolase; n=1;
Oceanobacter sp. RED65|Rep: Predicted amidohydrolase -
Oceanobacter sp. RED65
Length = 274
Score = 50.4 bits (115), Expect = 8e-05
Identities = 55/226 (24%), Positives = 88/226 (38%), Gaps = 26/226 (11%)
Query: 146 GPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRV-- 203
GP L+ LA + + II+ + D + +V G + ++ K H+ V
Sbjct: 67 GPVRSQLSALAKDFKVNIIAGSMPLMSSVEDKVLAACLVFAADGSEVCQYDKVHLFDVDV 126
Query: 204 ----GDFNESTYYFEGNTGHPVF--ETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNP 257
G + ES + G V T YG +++CY P + + ++V P
Sbjct: 127 SDNKGRYRESDTFIAGTQSKTVSLDGTLYG---LSVCYDLRFPELYQQYQKQSCQVVTVP 183
Query: 258 SATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGS 317
SA + W + AI + A N+VGT H+D +G
Sbjct: 184 SAFTYTTGQKHWLTLLKARAIETQSFVMAANQVGT---------------HEDGRITWGQ 228
Query: 318 SYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRL 363
S V PDG L K G L+ ++DL LC++I+ +RL
Sbjct: 229 SIVINPDGEIVGELDSEKAGELVVELDLELCQKIRQSMPLLKHKRL 274
>UniRef50_Q9HIW8 Cluster: Nitrilase related protein; n=2;
Thermoplasma|Rep: Nitrilase related protein -
Thermoplasma acidophilum
Length = 270
Score = 50.4 bits (115), Expect = 8e-05
Identities = 38/153 (24%), Positives = 70/153 (45%), Gaps = 4/153 (2%)
Query: 140 AEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH 199
+EP L G + E+A II I ER+ + +NTA+ I+E G ++ K+RK H
Sbjct: 56 SEP-LDGKFVKSITEIARSESQKIILNIPERNQYNLKP-FNTAIYIDELGLIL-KYRKLH 112
Query: 200 IPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSA 259
+ F ES+ + +G+ +F + + ICY P M ++GA+++ +
Sbjct: 113 LFDAFGFRESSVFEKGDARPAIFNGSGDPLGVLICYDLRFPEPARMLALDGAKLIIYQAG 172
Query: 260 TVSGLSEH-LWAVEARNAAIANSYYTCAINRVG 291
+G ++ W + A+ N + + G
Sbjct: 173 WFAGERKYDQWKTLLKARAMENGVFVIGAAQTG 205
>UniRef50_Q6JHR5 Cluster: Aliphatic amidase; n=1; Saccharopolyspora
spinosa|Rep: Aliphatic amidase - Saccharopolyspora
spinosa
Length = 308
Score = 49.6 bits (113), Expect = 1e-04
Identities = 27/83 (32%), Positives = 46/83 (55%), Gaps = 5/83 (6%)
Query: 178 IWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHP-VFETKYGKVAINICYG 236
++NTA+ + G +G +RK HIP +G + G+ G P VF+T +G+V + IC+
Sbjct: 113 VYNTALALGPAG-TLGHYRKQHIPFMG---ADRFVAPGDDGAPRVFDTPFGRVGMMICFD 168
Query: 237 RHHPLNWLMFGINGAEIVFNPSA 259
P + + GA+I+ P+A
Sbjct: 169 LRFPESARELALAGADIIVMPTA 191
>UniRef50_Q0W654 Cluster: Putative amidohydrolase; n=1; uncultured
methanogenic archaeon RC-I|Rep: Putative amidohydrolase
- Uncultured methanogenic archaeon RC-I
Length = 330
Score = 49.6 bits (113), Expect = 1e-04
Identities = 67/273 (24%), Positives = 117/273 (42%), Gaps = 30/273 (10%)
Query: 93 QRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFL 152
+R + ++ +I AA E ++ L E M + + E W AEPV GP+ +L
Sbjct: 25 ERESNLKRATPLIEKAAREGAQLVVLPE---MAASGYSIENSMWIA-AEPV-DGPTVQWL 79
Query: 153 AELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYY 212
E A + + + + E + G+ +NT V+ + G++ GK RK H ++N
Sbjct: 80 KETAKRLGIYLGIGVEEAE---GEDFYNTYVLASPDGRIAGKVRKVHT----EYN----I 128
Query: 213 FEGNTGHPVFETKYGKVAINICYGRHH---PLNW------LMFGINGAEIVFNPSATV-- 261
F+ G + +T+ G++ I IC H+ PL L+ + I F + V
Sbjct: 129 FKPGEGSRIIDTEIGRIGIGICADNHYIDMPLEMQEKSIDLLLMPHAWPIPFKAAGVVKE 188
Query: 262 SGLSEHLWAVEARNAAIAN--SYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSY 319
+ E V+ + A + +N VG P + G+ G S
Sbjct: 189 EDVREQQENVKGYSQLFARMLGVPSVFVNAVGPIG-PKRWEGILGRLIDPAVYRNAGYSS 247
Query: 320 VTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIK 352
++ DGS L +DG+++A V L+L R++K
Sbjct: 248 ISDSDGSLLARLGPEEDGVIVADVTLDLTRKLK 280
>UniRef50_P55175 Cluster: UPF0012 hydrolase sll0601; n=40;
Cyanobacteria|Rep: UPF0012 hydrolase sll0601 -
Synechocystis sp. (strain PCC 6803)
Length = 272
Score = 49.6 bits (113), Expect = 1e-04
Identities = 57/264 (21%), Positives = 112/264 (42%), Gaps = 31/264 (11%)
Query: 99 EKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVK 158
++ +++I A + ++ L E FAF E + + A + T FL +A +
Sbjct: 22 QEAEELIDLAVRQGAELVGLPEN----FAFLGNETEK-LEQATAIATATEK-FLQTMAQR 75
Query: 159 YDMVIISPILERDDIHGDT--IWNTAVVINEFGKVIGKHRKNH-----IPRVGDFNESTY 211
+ + I++ + G+ +NTA +I G+ + ++ K H +P + ES
Sbjct: 76 FQVTILAGGFPFP-VAGEAGKAYNTATLIAPNGQELARYHKVHLFDVNVPDGNTYWESAT 134
Query: 212 YFEGNTGHPVFET-KYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWA 270
G PV+ + +G + ++ICY P + GA+++F P+A + + W
Sbjct: 135 VMAGQKYPPVYHSDSFGNLGLSICYDVRFPELYRYLSRQGADVLFVPAAFTAYTGKDHWQ 194
Query: 271 VEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPG 330
V + AI N+ Y A + G H + H +G + + P G
Sbjct: 195 VLLQARAIENTCYVIAPAQTG---------------CHYERRHTHGHAMIIDPWGVILAD 239
Query: 331 LSRIKDGLLIAQVDLNLCRQIKDK 354
K GL IA+++ + +Q++ +
Sbjct: 240 AGE-KPGLAIAEINPDRLKQVRQQ 262
>UniRef50_Q3A0A3 Cluster: Predicted amidohydrolase; n=1; Pelobacter
carbinolicus DSM 2380|Rep: Predicted amidohydrolase -
Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
Length = 278
Score = 49.2 bits (112), Expect = 2e-04
Identities = 52/199 (26%), Positives = 85/199 (42%), Gaps = 22/199 (11%)
Query: 99 EKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVK 158
E + + AA + ++C E A C + + AE V+ G ++ LA LA K
Sbjct: 31 EGIARWTEQAARQGAEMVCFPE-----LAICGYTRSGIGELAE-VVPGRASCHLAALARK 84
Query: 159 YDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTG 218
+ MV+ + ++E+ G + T +V + G I ++RK H+ R E + G+
Sbjct: 85 HRMVVSAGLIEKS---GSACYITQLVASADGS-IERYRKTHLGR----REREVFCAGDA- 135
Query: 219 HPVFETKYGK-----VAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSE--HLWAV 271
PVF T+ AI +CY H P + + GA+++ P A + LW
Sbjct: 136 LPVFTTRSRAGMPITFAIGLCYDLHFPELATAYAVQGAQLLLAPHAAPHAGPDRMQLWQR 195
Query: 272 EARNAAIANSYYTCAINRV 290
A N+ Y A N V
Sbjct: 196 YMGARAYDNTMYVAACNHV 214
>UniRef50_A5WCY0 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=42; Bacteria|Rep:
Nitrilase/cyanide hydratase and apolipoprotein
N-acyltransferase - Psychrobacter sp. PRwf-1
Length = 545
Score = 49.2 bits (112), Expect = 2e-04
Identities = 50/201 (24%), Positives = 84/201 (41%), Gaps = 15/201 (7%)
Query: 97 IFEKVQKIISAAAAEQVNILCLQEAWNMPF-AFCTREKQPWCDFAEPVLTGPSTVF---L 152
+ ++V+ + A + CL E +N P C Q + A L + F +
Sbjct: 242 LLQQVEFFVDIMADYNADFACLPEFFNAPLMGLCESTDQ---NIAIRFLADYTEWFKNEI 298
Query: 153 AELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYY 212
+ LAV Y++ +I+ + D + + ++N + + G V + RK HI S +
Sbjct: 299 SNLAVSYNVNVITGSMPLFDENEEVLYNVSYLCRRDGTV-EEQRKIHIT---PHERSAWV 354
Query: 213 FEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNP--SATVSGLSEHLWA 270
EG VF+T G++ I ICY P + + +I+F P + T +G
Sbjct: 355 IEGGNKVQVFDTDAGRIGILICYDVEFPELARLLALEDMDILFVPFWTDTKNGYLRVRHC 414
Query: 271 VEARNAAIANSYYTCAINRVG 291
+AR AI N Y VG
Sbjct: 415 AQAR--AIENECYVMICGSVG 433
>UniRef50_Q5R0H6 Cluster: Predicted amidohydrolase, nitrilase
family; n=2; Idiomarina|Rep: Predicted amidohydrolase,
nitrilase family - Idiomarina loihiensis
Length = 265
Score = 48.8 bits (111), Expect = 2e-04
Identities = 51/211 (24%), Positives = 86/211 (40%), Gaps = 14/211 (6%)
Query: 86 TDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLT 145
+ P Q LAI V K++ A + ++ L EA++ F R + AEP
Sbjct: 2 SSRPDPQDNLAI---VAKLLEQLPAARPQLVVLPEAFSC-FGAGDRAQLA---MAEPYKD 54
Query: 146 GPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGD 205
G LA LA K+++ ++ L D G+ +++ G ++ ++ K H+ V
Sbjct: 55 GEVQKQLAALAKKHEVYLVGGTLPVDA--GERFSAASILFGPDGAILNRYDKIHLFDVDV 112
Query: 206 FNESTYYFEGNTGHP-----VFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSAT 260
+ + Y E P ET +G V + +CY P + G++I+ PSA
Sbjct: 113 ADNTKEYRESKWTQPGSKVVTTETDFGVVGMAVCYDLRFPELFRALRQAGSQIIVLPSAF 172
Query: 261 VSGLSEHLWAVEARNAAIANSYYTCAINRVG 291
+ W R AI + A +VG
Sbjct: 173 TQVTGKAHWHALVRARAIEQQVFIVAPGQVG 203
>UniRef50_Q3W243 Cluster: GCN5-related N-acetyltransferase:AIR
synthase related protein:Nitrilase/cyanide hydratase and
apolipoprotein N- acyltransferase:AIR synthase related
protein, C-terminal; n=14; Actinomycetales|Rep:
GCN5-related N-acetyltransferase:AIR synthase related
protein:Nitrilase/cyanide hydratase and apolipoprotein
N- acyltransferase:AIR synthase related protein,
C-terminal - Frankia sp. EAN1pec
Length = 807
Score = 48.8 bits (111), Expect = 2e-04
Identities = 36/109 (33%), Positives = 55/109 (50%), Gaps = 11/109 (10%)
Query: 146 GPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGD 205
GP LA A+ DMV+ + ERD G +N+AV ++ G V+G+HRK H P
Sbjct: 563 GPEITRLA--AIAGDMVVCAGYAERD---GRYRYNSAVCVHGDG-VLGRHRKVHQP---- 612
Query: 206 FNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIV 254
ES Y E F++ G++ + ICY + P + + GA+I+
Sbjct: 613 LGESLAY-EAGRSFTAFDSPLGRMGMMICYDKAFPESGRSLALAGADII 660
>UniRef50_Q1LPP8 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=5;
Betaproteobacteria|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Ralstonia
metallidurans (strain CH34 / ATCC 43123 / DSM 2839)
Length = 273
Score = 48.8 bits (111), Expect = 2e-04
Identities = 38/152 (25%), Positives = 68/152 (44%), Gaps = 8/152 (5%)
Query: 146 GPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHI----P 201
GP FLA+ A ++ + ++ L ++NT++ + G+ + ++ K H+
Sbjct: 68 GPVQSFLADAARRHRVWLVGGTLPMWCNDDARVYNTSLAFDPHGRRVARYDKIHLFGFTK 127
Query: 202 RVGDFNESTYYFEGNTGHPV-FETKYGKVAINICYGRHHP-LNWLMFGINGAEIVFNPSA 259
++ES G T PV F+ G+VA+++CY P L + G N ++ P+A
Sbjct: 128 GTESYDESRTILAGKT--PVAFDAPCGRVAMSVCYDLRFPELYRGLAGKNDVSLILMPAA 185
Query: 260 TVSGLSEHLWAVEARNAAIANSYYTCAINRVG 291
+ W + R AI N Y A + G
Sbjct: 186 FTYTTGQAHWEILLRARAIENQCYVLAAAQGG 217
>UniRef50_A6Q8M5 Cluster: Carbon-nitrogen hydrolase family protein;
n=1; Sulfurovum sp. NBC37-1|Rep: Carbon-nitrogen
hydrolase family protein - Sulfurovum sp. (strain
NBC37-1)
Length = 377
Score = 48.8 bits (111), Expect = 2e-04
Identities = 56/276 (20%), Positives = 115/276 (41%), Gaps = 25/276 (9%)
Query: 73 VRLGLIQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTRE 132
+RLG+ Q A+S + + ++++ I A + + +L E + +
Sbjct: 63 IRLGIYQAQ-AVSGEGATAKN----LKRMEHAIRLAKEKHIQLLSFPELYIPGYTLSPAM 117
Query: 133 KQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTI--WNTAVVINEFGK 190
+ F + GP+ ELA + ++ I+ P E+ T+ +++ VI+E GK
Sbjct: 118 VKKVAQFKD----GPAVTKARELARRNNIAILLPYAEKAKHSDGTLAYYDSIAVIDEHGK 173
Query: 191 VIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGING 250
++ +RK H+ G + F GN + V+ V + CY P + + G
Sbjct: 174 LLNSYRKTHL--YGQQERDNWSF-GNGDYQVYHFFGFPVGVLNCYECEFPELSRILALKG 230
Query: 251 AEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNE-FTSGDGKPAH- 308
A+++ P+A + + + + + Y + + ++ N F + + +
Sbjct: 231 AKLIVGPTAA----DNYYTLPDGKRSNV--PYPDISKTLIPAYAYANNIFFAYSNRAGYE 284
Query: 309 ---KDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIA 341
KD H+ G+S +T P G + +D +LIA
Sbjct: 285 RRGKDQWHYRGNSIITGPHGDIIVAANHEQDTMLIA 320
>UniRef50_A3EPK6 Cluster: Putative carbon-nitrogen hydrolase; n=1;
Leptospirillum sp. Group II UBA|Rep: Putative
carbon-nitrogen hydrolase - Leptospirillum sp. Group II
UBA
Length = 273
Score = 48.8 bits (111), Expect = 2e-04
Identities = 55/224 (24%), Positives = 96/224 (42%), Gaps = 27/224 (12%)
Query: 146 GPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGD 205
GP+ FL E +++ ++ + R G+ ++N+AVV + G V+ + K H+
Sbjct: 72 GPTVRFLEEFSMETKGWVVGGLPLR---RGNKVYNSAVVTHH-GTVMAIYDKTHL----- 122
Query: 206 FNESTYYFEGNTGHP-VFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGL 264
F +FE +G + T++G + + IC+ P ++GA ++ +P V
Sbjct: 123 FEAENRWFERGSGPLCLVRTEFGLMGVMICFDWLFPEVTRSLALSGALLIAHPVNWVLPF 182
Query: 265 SEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPD 324
+ ++ N +T NRVG E+ G KP + GSS V +P
Sbjct: 183 GPQGMILR----SVENRVFTATANRVGEEA------RGGFKPL-----RYIGSSQVVSPQ 227
Query: 325 GSRTPGLSRIKDGLLIAQVDLNLCR--QIKDKWGFTMTQRLDLY 366
G + LL Q D L R ++ ++ F +R DLY
Sbjct: 228 GEILARAPEEAESLLEIQCDPELARSKRVVEESDFFRQRRPDLY 271
>UniRef50_A0RNK8 Cluster: Hydrolase, carbon-nitrogen family; n=13;
Campylobacter|Rep: Hydrolase, carbon-nitrogen family -
Campylobacter fetus subsp. fetus (strain 82-40)
Length = 268
Score = 48.8 bits (111), Expect = 2e-04
Identities = 50/211 (23%), Positives = 87/211 (41%), Gaps = 24/211 (11%)
Query: 152 LAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHI-PRVGDFNEST 210
L LA KYD++I++PI+ + G I+ V+ +F K+ + +I +NES
Sbjct: 67 LLNLAKKYDLIIVAPIIL---LKGKDIYK---VVAKFSPQSVKYEEQNIFIDYSHWNESK 120
Query: 211 YYFEGNTGH-PVFETKYGKVAINICYG--RHHPLNWLMFGINGAEIVFNPSATVSGLSEH 267
++ + Y K + +G H W + V P+A S+
Sbjct: 121 FFKSSKKDSLGIMSFAYDKFKFGVMFGYETHFDRLWQEMMSKKIDCVLVPTACTLN-SKD 179
Query: 268 LWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSR 327
W + A N+ Y NR+G F +E +S FYG+S + +P G
Sbjct: 180 RWNELLKMRAFTNNVYILRANRLGKAKF-DEVSS-----------EFYGNSMLISPHGEI 227
Query: 328 TPGLSRIKDGLLIAQVDLNLCRQIKDKWGFT 358
L +G+L+ ++D L + + W F+
Sbjct: 228 MDSLD-TNEGMLVCELDKKLLNEARSIWKFS 257
>UniRef50_Q74FF8 Cluster: Hydrolase, carbon-nitrogen family; n=6;
Geobacter|Rep: Hydrolase, carbon-nitrogen family -
Geobacter sulfurreducens
Length = 283
Score = 48.4 bits (110), Expect = 3e-04
Identities = 46/173 (26%), Positives = 81/173 (46%), Gaps = 12/173 (6%)
Query: 179 WNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRH 238
+NT++ + E G+V HRK ++P G F+E Y G F++++G++ + IC
Sbjct: 93 FNTSLYL-EGGEVRHVHRKVYLPTYGLFDEQRYLARGEHFR-AFDSRFGRMGLLICEDMW 150
Query: 239 HPLNWLMFGINGAEIVFNPSATVS-GLSEHLWAVEARNAAIANSYYTCAINRVGTESFPN 297
H + ++GA V S++ GL+E ++ + IA T T F N
Sbjct: 151 HLSAPYILAMDGATTVICLSSSPGRGLTED----DSLGSTIAWQKLTST-----TAMFFN 201
Query: 298 EFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQ 350
+ ++D +F+G S V AP G+ T +++ L+A VD R+
Sbjct: 202 CRVLYCNRVGYEDGVNFWGGSEVVAPSGAVTSRARILEEDFLVAGVDEGALRR 254
>UniRef50_Q127K6 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=12; root|Rep:
Nitrilase/cyanide hydratase and apolipoprotein
N-acyltransferase - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 313
Score = 48.4 bits (110), Expect = 3e-04
Identities = 52/204 (25%), Positives = 86/204 (42%), Gaps = 11/204 (5%)
Query: 144 LTGPSTVFLAELAVKYDMVIISPILERD-DIHGDTIWNTAVVINEFGKVIGKHRKNHIPR 202
L G L E A +++ I+ I ERD + G T++NT V I G+V +HRK +P
Sbjct: 78 LGGGDLAELCEAARAHNVTIVCGINERDRERGGGTLYNTVVTIGADGRVQNRHRK-LMPT 136
Query: 203 VGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVS 262
+ + +G V +T G++ IC+ + PL G EI P+
Sbjct: 137 --NPERMVHGLGDASGLRVVDTPAGRIGCLICWENYMPLARYALYAQGVEIYIAPTYD-- 192
Query: 263 GLSEHLWAVEARNAAIANSYYTCAI-NRVGTESFPNEFTS-GDGKPAHKDFGHFYGSSYV 320
S W R+ A+ + + P +F + + P +++ + G S V
Sbjct: 193 --SGDAWIGTMRHIALEGRCWVVGSGTALRASDIPQDFPARAELFPDPEEWIN-DGDSVV 249
Query: 321 TAPDGSRTPGLSRIKDGLLIAQVD 344
P G G R + G+L A++D
Sbjct: 250 VDPMGKVVAGPLRREAGILYAEID 273
>UniRef50_A1SU00 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Psychromonas
ingrahamii 37|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Psychromonas
ingrahamii (strain 37)
Length = 274
Score = 48.4 bits (110), Expect = 3e-04
Identities = 44/178 (24%), Positives = 69/178 (38%), Gaps = 9/178 (5%)
Query: 127 AFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVIN 186
A C +K + +E + G L+ LA Y +I D I+ T +V +
Sbjct: 44 ALCIADKDHYLALSENLGKGYYQSLLSALAKHYQCYLICGSFPIKSTITDKIFTTCLVFS 103
Query: 187 EFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETK--------YG-KVAINICYGR 237
G++I + K H+ + Y E +T P E K Y KV + ICY
Sbjct: 104 PLGELISHYHKMHLFDAQVADHKGIYKESDTFVPGQEVKLFNWDCGAYSVKVGLTICYDL 163
Query: 238 HHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESF 295
P + GA+I+ P+A + W + AI N Y A N+ E++
Sbjct: 164 RFPGLFQTLRKQGADILLVPAAFTQTTGQAHWLPLLQARAIENQCYIIAANQSSHETY 221
>UniRef50_Q0HEI5 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=18; Shewanella|Rep:
Nitrilase/cyanide hydratase and apolipoprotein
N-acyltransferase - Shewanella sp. (strain MR-4)
Length = 282
Score = 48.0 bits (109), Expect = 4e-04
Identities = 38/156 (24%), Positives = 69/156 (44%), Gaps = 6/156 (3%)
Query: 152 LAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTY 211
L+ LA +Y + +++ + G +++ + ++ G +G++ K H+ V + +
Sbjct: 75 LSALAARYCVYMVAGTIPALAEDG-RVYSRCYLFDDKGDTLGQYDKLHLFDVDVADGTKQ 133
Query: 212 YFEGNTGHP-----VFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSE 266
Y E T P V +T +GK+ + ICY P + + GAEI+ PSA E
Sbjct: 134 YRESETFCPGNHISVIDTPFGKIGLTICYDLRFPDLFRALRLAGAEIITVPSAFTKVTGE 193
Query: 267 HLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSG 302
W V + AI + A + G + + T G
Sbjct: 194 AHWQVLLQARAIETQCFILAAAQWGAHNEGSRETWG 229
>UniRef50_A4BGL8 Cluster: Predicted amidohydrolase; n=1; Reinekea
sp. MED297|Rep: Predicted amidohydrolase - Reinekea sp.
MED297
Length = 271
Score = 48.0 bits (109), Expect = 4e-04
Identities = 32/114 (28%), Positives = 53/114 (46%), Gaps = 7/114 (6%)
Query: 184 VINEFGKVIGKHRKNHI------PRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGR 237
V++ G+++G + K H+ R G + ES Y G+ + T +G++ +++CY
Sbjct: 104 VVDADGELVGFYDKIHLFDAEVGDRQGAYRESDSYSGGDKVVTLL-TPWGRLGLSVCYDL 162
Query: 238 HHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVG 291
P + GA+ V PSA + E W R AI N Y A+N+ G
Sbjct: 163 RFPELFRALNDQGADFVTLPSAFTAKTGEAHWEPLCRARAIENGYSLIAVNQCG 216
>UniRef50_Q8KFP8 Cluster: Carbon-nitrogen hydrolase family protein;
n=1; Chlorobaculum tepidum|Rep: Carbon-nitrogen
hydrolase family protein - Chlorobium tepidum
Length = 271
Score = 47.6 bits (108), Expect = 5e-04
Identities = 69/264 (26%), Positives = 105/264 (39%), Gaps = 33/264 (12%)
Query: 89 PITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPS 148
P +R A E ++ ++ A+ I+ L E + + F +RE+ FAE G +
Sbjct: 11 PRLGERQANLEAIRSLLDPVEAD---IVVLPELCSSGYFFTSREEL--APFAESP-GGVA 64
Query: 149 TVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNE 208
F LA +II+ + E +N+ V +RK+H+ F +
Sbjct: 65 CSFFQGLADAKRAIIIAGMPETAQ---GCFYNSVFVFRPGVADPLVYRKSHL-----FYK 116
Query: 209 STYYFE-GNTGHPVFETKYGKVAINI--CYGRHHPLNWLMFGINGAEIVFNPSATVSGLS 265
+ FE G+TG PV + ++I I CY P + + GA+++ PS V+
Sbjct: 117 ERFVFEPGDTGFPVIRDEQLDISIGIMLCYDWRFPEVSRVLALGGADLIACPSNLVTDA- 175
Query: 266 EHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDG 325
W AI N Y NR GTE T GD K G S V P G
Sbjct: 176 ---WRKVMPARAIENKLYVAVANRCGTE------TRGDETLLFK------GCSAVYDPYG 220
Query: 326 SRTPGLSRIKDGLLIAQVDLNLCR 349
D +L+A++D CR
Sbjct: 221 ETVALADADNDRVLLAEIDPRSCR 244
>UniRef50_Q4KB18 Cluster: Hydrolase, carbon-nitrogen family; n=2;
Bacteria|Rep: Hydrolase, carbon-nitrogen family -
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 325
Score = 47.6 bits (108), Expect = 5e-04
Identities = 52/200 (26%), Positives = 83/200 (41%), Gaps = 14/200 (7%)
Query: 152 LAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTY 211
L E A + ++ + ER HG +++N+ V I G ++ HRK E T
Sbjct: 95 LREAARVNSVTVVMGMNERSRRHGGSLYNSLVTIGPEGTILNVHRK----LTPTHTERTV 150
Query: 212 YFEGN-TGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWA 270
+ G+ G V +T G+V +C+ HPL +I A ++E +
Sbjct: 151 WANGDAAGLRVVDTAVGRVGGLVCWEHWHPLARQALHAQDEQI---HVAAWPDMTE-MHH 206
Query: 271 VEARNAAI-ANSYYTCAINRVGTESFPNE----FTSGDGKPAHKDFGHFYGSSYVTAPDG 325
V AR+ A + CA + P E + G G ++ F G S V APDG
Sbjct: 207 VAARSYAFEGRCFVLCAGQYLNVADVPAELLTAYRLGVGGNGLEERLLFNGGSGVVAPDG 266
Query: 326 SRTPGLSRIKDGLLIAQVDL 345
S + G+++A +DL
Sbjct: 267 SWVTAPLFGEPGIVLATIDL 286
>UniRef50_A0R400 Cluster: Hydrolase, carbon-nitrogen family protein;
n=1; Mycobacterium smegmatis str. MC2 155|Rep:
Hydrolase, carbon-nitrogen family protein -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 281
Score = 47.6 bits (108), Expect = 5e-04
Identities = 36/126 (28%), Positives = 59/126 (46%), Gaps = 9/126 (7%)
Query: 172 DIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAI 231
++ GDT++N+A+VI + GKV+G +RK H+ E + G V +T ++ +
Sbjct: 90 EVDGDTLYNSAIVIGD-GKVVGTYRKAHLWAA----EPEIFATGVEAGTVIDTAICRLGV 144
Query: 232 NICYGRHHPLNWLMFGINGAEIVFNP---SATVSGLSEHL-WAVEARNAAIANSYYTCAI 287
ICY P + GAE++ P EH ++A AA ++ T
Sbjct: 145 AICYDNEFPELPRRLALRGAEVLALPVNWPLVDRPEGEHAPETIQAMAAARSSQLATVIA 204
Query: 288 NRVGTE 293
+R GTE
Sbjct: 205 DRRGTE 210
>UniRef50_Q4Q8W4 Cluster: Nitrilase, putative; n=6;
Trypanosomatidae|Rep: Nitrilase, putative - Leishmania
major
Length = 279
Score = 47.6 bits (108), Expect = 5e-04
Identities = 59/282 (20%), Positives = 113/282 (40%), Gaps = 27/282 (9%)
Query: 90 ITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPST 149
+T+++ A +K +I+ AA + L E +N P+ + + +++E + G T
Sbjct: 14 VTREKAANIKKAVTMITEAAKRGSKLAVLPECFNCPYG-----TKYFDEYSEALAPGNET 68
Query: 150 VFLAELAVKYDMV-IISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGD--- 205
K + + I++ + G ++N+++ G + HRK H+ +
Sbjct: 69 FDAMSQCAKANSIWIVAGSIPEKSADGK-LFNSSMTFGSDGALKHVHRKVHLFCINTDTV 127
Query: 206 -FNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGL 264
F+ES GN + ++ K + IC+ +P + G + P A
Sbjct: 128 RFDESEVLSAGNDATAISLDEHTKFGVAICFDIRYPFLAWKYAEQGTSFIVYPGAFNMVT 187
Query: 265 SEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPD 324
W + AR A+ N Y + P TS + + +GH S V P
Sbjct: 188 GPMHWQLAARARAVDNQQYVFVCS-------PARDTSAE----YVAWGH----SMVVDPI 232
Query: 325 GSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
G+ L K+G + +VDL++ + +++ R DLY
Sbjct: 233 GNVLSELDE-KEGFVDWKVDLSVIQDTRNRIPILKGVRDDLY 273
>UniRef50_A1RZK0 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Thermofilum
pendens Hrk 5|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Thermofilum pendens
(strain Hrk 5)
Length = 286
Score = 47.6 bits (108), Expect = 5e-04
Identities = 38/123 (30%), Positives = 56/123 (45%), Gaps = 6/123 (4%)
Query: 175 GDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYG-KVAINI 233
G ++N AV+ E GKV +RK H+ + ES+ + G PV G ++ I +
Sbjct: 102 GPGVYNAAVLAEE-GKVKAVYRKIHLFDAYGYRESSVFSPGR--EPVVADLKGLRLGIAV 158
Query: 234 CYGRHHPLNWLMFGINGAEIVFNPSATVSG-LSEHLWAVEARNAAIANSYYTCAINRVGT 292
C+ P + + GAE+ PSA G W A N+ Y A+N+VG
Sbjct: 159 CFDLRFPELFRSMFLRGAEVFVVPSAWYRGPYKVEQWKALTAARAHENTSYLVAVNQVG- 217
Query: 293 ESF 295
ESF
Sbjct: 218 ESF 220
>UniRef50_Q30T00 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Thiomicrospira
denitrificans ATCC 33889|Rep: Nitrilase/cyanide
hydratase and apolipoprotein N-acyltransferase -
Thiomicrospira denitrificans (strain ATCC 33889 / DSM
1351)
Length = 260
Score = 47.2 bits (107), Expect = 7e-04
Identities = 38/141 (26%), Positives = 59/141 (41%), Gaps = 8/141 (5%)
Query: 153 AELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYY 212
+ LA KY+ ++ + +D GD N AV I++ G V+GK+ K H P F Y
Sbjct: 68 SSLAKKYNTALVFGVAIKD---GDKALNKAVFIDKNGSVLGKYSKIH-PFT--FAGEDKY 121
Query: 213 FEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVE 272
F + + K+ + ICY P + ++V N + H W
Sbjct: 122 FNAGNSLEIVNFENFKIGLTICYDLRFPELYSSLA-KSCDLVINIANWPFKRVAH-WNTL 179
Query: 273 ARNAAIANSYYTCAINRVGTE 293
+ AI N + INRVG +
Sbjct: 180 LKARAIENQIFIAGINRVGVD 200
>UniRef50_A6X6J7 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Ochrobactrum
anthropi ATCC 49188|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Ochrobactrum anthropi
(strain ATCC 49188 / DSM 6882 / NCTC 12168)
Length = 279
Score = 47.2 bits (107), Expect = 7e-04
Identities = 44/159 (27%), Positives = 67/159 (42%), Gaps = 8/159 (5%)
Query: 140 AEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH 199
AE V GP+ + A ++ + + + L + I+N+ V N GK I +RK H
Sbjct: 57 AESVPGGPAYKMAQDFAREHKVFVHAGTLMEKVPNEKRIYNSTFVFNREGKEIAHYRKIH 116
Query: 200 I-PRVGDFNESTYYFEGNTGHP-----VFETKYGKVAINICYGRHHPLNWLMFGINGAEI 253
+ VG + T Y E T P V++ KV ICY +L GA++
Sbjct: 117 MFDIVGP--DGTAYKESATVKPGENVVVYDLDGFKVGCAICYDIRFAELYLELEKAGADV 174
Query: 254 VFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGT 292
+ P+A + W V AR AI Y A + G+
Sbjct: 175 IVLPAAFTLQTGKDHWEVLARARAIETQTYFAACGQTGS 213
>UniRef50_A5G317 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=5;
Proteobacteria|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Acidiphilium cryptum
(strain JF-5)
Length = 284
Score = 47.2 bits (107), Expect = 7e-04
Identities = 63/259 (24%), Positives = 105/259 (40%), Gaps = 29/259 (11%)
Query: 104 IISAAAAEQVNILCLQEAWNM---PFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYD 160
I +A AA++ ++ L E W+ A T + G + FL E A ++
Sbjct: 31 IDAAVAADRPGLVSLPEVWSCLGGDRAAKTEAAEVLPAAGSGETGGDAYEFLRETARRHR 90
Query: 161 MVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHI-----PRVGDFNESTYYFEG 215
+ + + GD ++NT +V + G+ I ++RK H+ P + ES Y
Sbjct: 91 IHVHGGSIGEQG--GDRLYNTTLVFDPDGREIARYRKIHLFDITTPDGQGYRESATY--- 145
Query: 216 NTGHPVFETKYG--KVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEA 273
G V + G V ++ICY P +L GA+++ P+A + W V
Sbjct: 146 GAGDAVVTCRIGGLTVGLSICYDMRFPELYLALHRAGADLIMVPAAFTLQTGKDHWDVLL 205
Query: 274 RNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSR 333
R AI + A VG P+ G+ + YG+S + P GS ++R
Sbjct: 206 RARAIETQCWIAAAACVG----PHRDGRGETR-------FTYGNSLIADPWGSI---VAR 251
Query: 334 IKDGLLIAQVDLNLCRQIK 352
+ DG A ++ R K
Sbjct: 252 VSDGPGFATARIDPARGAK 270
>UniRef50_Q82UY9 Cluster: Carbon-nitrogen hydrolase; n=50;
Proteobacteria|Rep: Carbon-nitrogen hydrolase -
Nitrosomonas europaea
Length = 287
Score = 46.8 bits (106), Expect = 0.001
Identities = 51/215 (23%), Positives = 95/215 (44%), Gaps = 18/215 (8%)
Query: 96 AIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTV--FLA 153
A E+ ++I AAA+Q ++ L E FC + A G + FL+
Sbjct: 36 ANLEEAFRLIEEAAAKQAKLVVLPEY------FCIMGMKDTDKLAVRENPGEGEIQNFLS 89
Query: 154 ELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYF 213
E A ++ + + + D ++N+ +V +E G+ + ++ K H+ + NE+ +
Sbjct: 90 ETAKRFGIWLAGGSVPLISPVSDKVYNSCLVYDEHGQQVARYDKIHLFGLSLGNEN--FA 147
Query: 214 EGNT---GHPV--FETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHL 268
E T G+ V ++ +G++ ++ICY P + M G +++ P+A + +
Sbjct: 148 EERTIDAGNRVVALDSPFGRMGLSICYDLRFPELYRMMG--KVDVILAPAAFTAITGKAH 205
Query: 269 WAVEARNAAIANSYYTCAINRVGTESFPNEFTSGD 303
W R AI N Y A + G E T+GD
Sbjct: 206 WETLIRARAIENQAYLIAPAQGGFHVNGRE-TNGD 239
>UniRef50_Q28TG7 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=2; Jannaschia sp.
CCS1|Rep: Nitrilase/cyanide hydratase and apolipoprotein
N-acyltransferase - Jannaschia sp. (strain CCS1)
Length = 298
Score = 46.8 bits (106), Expect = 0.001
Identities = 33/117 (28%), Positives = 53/117 (45%), Gaps = 6/117 (5%)
Query: 180 NTAVVINEFGKVIGKHRKNHIPRV-----GDFNESTYYFEGNTGHPVFETKYGKVAINIC 234
N V++ G ++ ++ K H+ V ES Y G+ V +T +G +A++IC
Sbjct: 99 NHTVLVAPSGDIVARYDKIHLFDVFLDGRRATGESDRYAPGSEA-VVADTPFGPMALSIC 157
Query: 235 YGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVG 291
Y P + + + G+ ++F PSA W V R AI N Y A +VG
Sbjct: 158 YDLRFPHLYRDYALAGSTVMFIPSAFTVPTGRAHWEVLLRARAIENGAYVIAAAQVG 214
>UniRef50_A7FDR9 Cluster: Hydrolase, carbon-nitrogen family protein;
n=16; Enterobacteriaceae|Rep: Hydrolase, carbon-nitrogen
family protein - Yersinia pseudotuberculosis IP 31758
Length = 289
Score = 46.8 bits (106), Expect = 0.001
Identities = 44/161 (27%), Positives = 74/161 (45%), Gaps = 12/161 (7%)
Query: 140 AEPVLTGPSTVFLAELAVKYDMVI---ISPILERDDIHGDTIWNTAVVINEFGKVIGKHR 196
AE GP + E+A +Y + I P++ R+ D I +++++ ++ G++ ++
Sbjct: 57 AEQHNDGPLQQEVREMARRYGVWIQVGSMPMVSRES--PDLITSSSLLFDDQGELKARYD 114
Query: 197 KNHIPRVGDFNE-STYYFEGNTGHP-----VFETKYGKVAINICYGRHHPLNWLMFGING 250
K H+ V D N+ +Y E +T P V +T G++ + ICY P + G
Sbjct: 115 KIHMFDV-DINDIHGHYRESDTYQPGQQLTVVDTPVGRLGMTICYDLRFPGLFQALRAQG 173
Query: 251 AEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVG 291
AEI+ P+A E W R AI N A +VG
Sbjct: 174 AEIISVPAAFTKMTGEAHWETLLRARAIENQCVILAAAQVG 214
>UniRef50_A4XN12 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1;
Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
Nitrilase/cyanide hydratase and apolipoprotein
N-acyltransferase - Caldicellulosiruptor saccharolyticus
(strain ATCC 43494 / DSM 8903)
Length = 287
Score = 46.8 bits (106), Expect = 0.001
Identities = 45/166 (27%), Positives = 78/166 (46%), Gaps = 11/166 (6%)
Query: 93 QRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFL 152
+R ++E + +I AA + +++ EA N R K + +P L G + +
Sbjct: 31 KRKTLYE-ICYLIEQAAKDHPDLIVTPEAVNAIIPSNKRTKF-FKQLTDP-LDGETVKKV 87
Query: 153 AELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYY 212
E+A KY I+ + + + +N+A+ IN G ++ + K H+ VG E T
Sbjct: 88 CEIAKKYRCNIVVGLYTSRE---NKAYNSALFINRKGDIVDVYDKVHLA-VG---EETNL 140
Query: 213 FEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPS 258
GN VF+T GKV I IC+ P + ++GA+I+ P+
Sbjct: 141 CPGNE-FKVFDTDIGKVGILICWDMQFPEAARILALSGADIIICPT 185
>UniRef50_A3Y529 Cluster: Putative uncharacterized protein; n=1;
Marinomonas sp. MED121|Rep: Putative uncharacterized
protein - Marinomonas sp. MED121
Length = 277
Score = 46.8 bits (106), Expect = 0.001
Identities = 32/110 (29%), Positives = 47/110 (42%), Gaps = 2/110 (1%)
Query: 183 VVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHP-L 241
V + G+ + + K H GD E Y+ GN VFE + I ICY P L
Sbjct: 103 VTLGRNGEYLTHYDKIHTAEYGDAAELKYFKRGNH-LSVFEVDGVRAGIIICYDMRFPEL 161
Query: 242 NWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVG 291
+ G +++ +P A LS H W + A+ N Y +IN+ G
Sbjct: 162 IRRLCGEFSVDVILHPVAFAQDLSFHTWKQFVVSRALENQVYFMSINQSG 211
>UniRef50_Q23ND3 Cluster: Hydrolase, carbon-nitrogen family protein;
n=1; Tetrahymena thermophila SB210|Rep: Hydrolase,
carbon-nitrogen family protein - Tetrahymena thermophila
SB210
Length = 284
Score = 46.8 bits (106), Expect = 0.001
Identities = 49/215 (22%), Positives = 89/215 (41%), Gaps = 12/215 (5%)
Query: 91 TQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTV 150
T + E + + + A +Q I EA FA +R + AE + G
Sbjct: 17 THNKKQNMEFILQNLKQAHEKQAKICFFPEA----FAMISRSFAETFENAE-YIDGEMIN 71
Query: 151 FLAELAVKYDMVI-ISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH-----IPRVG 204
L + A KY++ + + ER + + NT ++I+ G ++ ++K H I
Sbjct: 72 CLRDHAKKYNLWLSLGGFQERLKENDKKMGNTHIIIDNLGNIVQTYKKLHLFDISIDTKN 131
Query: 205 DFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGING-AEIVFNPSATVSG 263
+ES+ Y G+ V ++ G++ ++ICY P + + + AEI+ PSA
Sbjct: 132 TISESSGYVFGDQVPNVVDSPAGRLGLSICYDLRFPELFRLLAVQQKAEILLVPSAFFKK 191
Query: 264 LSEHLWAVEARNAAIANSYYTCAINRVGTESFPNE 298
+ W + AI N + A + G + E
Sbjct: 192 TGQAHWHTLLKARAIENQCFVIAAAQAGQHNDKRE 226
>UniRef50_Q7WM47 Cluster: Putative uncharacterized protein; n=2;
Bordetella|Rep: Putative uncharacterized protein -
Bordetella bronchiseptica (Alcaligenes bronchisepticus)
Length = 276
Score = 46.4 bits (105), Expect = 0.001
Identities = 54/236 (22%), Positives = 102/236 (43%), Gaps = 22/236 (9%)
Query: 108 AAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPI 167
AAA N++ L E F +R++ + GPST ++++ + I++ +
Sbjct: 33 AAAAGANLIVLPECCVGGLVFDSRDE---IRAVSETVPGPSTRAWSQVSRETGAWIVAGL 89
Query: 168 LERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYG 227
E D G I+NTAV++ G+ + +HRK H+ + F+ +T G
Sbjct: 90 SETD---GAKIYNTAVLVGPNGE-LHRHRKLHVRGI-----EQRLFDVGDALTCVDTPLG 140
Query: 228 KVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNA-AIANSYYTCA 286
++ + ICY P + ++G ++V P + S+ + +A +A + Y+ A
Sbjct: 141 RIGLAICYDMWFPEVCRNYALDGVDVVAAP----ANWSKSVRTADAFDAYGLPQGYHLMA 196
Query: 287 INRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDG-SRTPGLSRIKDGLLIA 341
V E + D + F G+S + P G + P SR ++ +L+A
Sbjct: 197 ATAVSNELV---VVAADRVGTERGVA-FLGTSCIFGPSGEALCPAASRGEEQILLA 248
>UniRef50_Q7MQY7 Cluster: Putative uncharacterized protein; n=1;
Wolinella succinogenes|Rep: Putative uncharacterized
protein - Wolinella succinogenes
Length = 257
Score = 46.4 bits (105), Expect = 0.001
Identities = 51/210 (24%), Positives = 87/210 (41%), Gaps = 23/210 (10%)
Query: 152 LAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTY 211
+ E + Y ++I+P++ ++ + V+ ++ G+V H++ IP +NE+ +
Sbjct: 66 IREFSKIYSTILIAPLVI---FKKGKLYKSLVIASK-GEVQFYHQQRLIP-FDHWNEARF 120
Query: 212 YF----EGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEH 267
+ + PVFE K+A Y H WL F ++ PSA+ S +
Sbjct: 121 FANSLPKSPKNPPVFEIDGIKIAPLFGYEAHFDEFWLKFKRLDVDLALIPSASTFD-SLN 179
Query: 268 LWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSR 327
W + A NS Y NRVG + S K FYG + P+G
Sbjct: 180 RWREMLKTRAFLNSCYILRANRVG----EYQMESSTWK--------FYGDTLWVKPNGEI 227
Query: 328 TPGLSRIKDGLLIAQVDLNLCRQIKDKWGF 357
L K+ LL+ ++D +I+ W F
Sbjct: 228 EDSLGE-KEELLLGELDQGYLEEIRRSWAF 256
>UniRef50_A0LQU6 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Acidothermus
cellulolyticus 11B|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Acidothermus
cellulolyticus (strain ATCC 43068 / 11B)
Length = 272
Score = 46.4 bits (105), Expect = 0.001
Identities = 57/206 (27%), Positives = 90/206 (43%), Gaps = 25/206 (12%)
Query: 99 EKVQKIIS-AAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPV--LTGPSTVFLAEL 155
++V +++ A+ +++ L E W +P AF +R FAE L GP L +
Sbjct: 18 DRVDRVVDLVASCRDADLVVLPELW-VPGAFASRF------FAEVATELPGPIIPRLGAV 70
Query: 156 AVKYDMVIIS-PILERDDIHGDTI-WNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYF 213
A + I++ +ER D D I +NTAV++N G + +RK H+ + E+
Sbjct: 71 AKELGAFIMAGTFIERADPATDRIGYNTAVLLNPDGAIAHTYRKVHLFGFHE-GEARMLA 129
Query: 214 EGN-------TGHPVFET-KYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLS 265
GN G + ET YG + CY P + + G +++ PS +
Sbjct: 130 AGNDVTTCRLEGGRMTETATYG---TSTCYDLRFPELYRILVDQGCDLLVIPSGWPAQRL 186
Query: 266 EHLWAVEARNAAIANSYYTCAINRVG 291
EH W V R AI N + A N G
Sbjct: 187 EH-WRVLTRARAIENQLFVVACNETG 211
>UniRef50_Q4WEA8 Cluster: Hydrolase, carbon-nitrogen family,
putative; n=1; Aspergillus fumigatus|Rep: Hydrolase,
carbon-nitrogen family, putative - Aspergillus fumigatus
(Sartorya fumigata)
Length = 321
Score = 46.4 bits (105), Expect = 0.001
Identities = 49/189 (25%), Positives = 81/189 (42%), Gaps = 11/189 (5%)
Query: 169 ERDDIHGDTIWNTAVVINEFGKVIGKHRKNHI--PRVGDFNESTYYFEGNTGHPVFETKY 226
E D G ++NTA I+ G ++G ++K +I P S G H VF+T
Sbjct: 121 EADGKEGFNLYNTAYFISNDGSILGSYQKKNIWHPERPHLTSS-----GEAPHEVFDTPI 175
Query: 227 GKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCA 286
GKV + IC+ P + +GAE+V P+ G H + EA + +S
Sbjct: 176 GKVGLLICWDLAFPEAFRELIASGAEVVIIPTFYHQGTC-HDASPEALSYN-PDSEALFL 233
Query: 287 INRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLN 346
+ + + F N A D F G S VT P + R ++G+L+ +D+
Sbjct: 234 ESTLTSRCFENTCAIVFVNAAGAD-EKFLGMSRVTLPIVGPVGKMGR-EEGVLVVDMDMG 291
Query: 347 LCRQIKDKW 355
L + ++ +
Sbjct: 292 LLKIAEENY 300
>UniRef50_A6SN02 Cluster: Nitrilase; n=3; Sclerotiniaceae|Rep:
Nitrilase - Botryotinia fuckeliana B05.10
Length = 1187
Score = 46.4 bits (105), Expect = 0.001
Identities = 47/191 (24%), Positives = 80/191 (41%), Gaps = 14/191 (7%)
Query: 173 IHGDT--IWNTAVVINEFGKVIGKHRKNHI--PRVGDFNESTYYFEGNTGHPVFETKYGK 228
+H +T + NTA I+ GK++ + K ++ P ST N H F+T GK
Sbjct: 109 LHPETSHLHNTAHFISPEGKIVSSYNKKNLWHPERPHLTSST-----NDAHTTFDTPLGK 163
Query: 229 VAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAIN 288
V + IC+ P + GA+I+ P T LS+ A ARN+ + +
Sbjct: 164 VGMLICWDAAFPEAFRELVSQGAKIIIIP--TFWTLSDCTPAGLARNSLSEELFVQSTLV 221
Query: 289 RVGTESFPNEFTSGDGKPA--HKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLN 346
E+ G P K+ F G S VT P + R ++G+ + ++D+
Sbjct: 222 SRAFENTCGIIFCNAGAPVGKGKEDSGFLGISQVTVPFQGALGKMGR-EEGMNVVELDMQ 280
Query: 347 LCRQIKDKWGF 357
+ ++ + F
Sbjct: 281 ILEDAEEAYKF 291
>UniRef50_Q8FM85 Cluster: Putative uncharacterized protein; n=2;
Corynebacterium|Rep: Putative uncharacterized protein -
Corynebacterium efficiens
Length = 296
Score = 46.0 bits (104), Expect = 0.002
Identities = 49/176 (27%), Positives = 77/176 (43%), Gaps = 14/176 (7%)
Query: 94 RLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLA 153
++A E V+ + AAA+ +L EA + F ++Q AE + TG +
Sbjct: 47 KMANLELVRTTATDAAAQGARLLIYPEATSQAFGTGRLDEQ-----AEDLHTGAFATGVQ 101
Query: 154 ELAVKYDMVIISPI------LERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFN 207
+LA +VI++ + +E+D + NTA+V G G H+ N G +
Sbjct: 102 QLAEDLGVVIVAGMFTPADTVEQDGKTLHRVHNTALVTGN-GLHEGYHKINTYDAFG-YR 159
Query: 208 ESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSG 263
ES GN H VF+ KV + ICY P + GAEI+ P++ G
Sbjct: 160 ESDTVKPGNELH-VFDLDGVKVGVAICYDLRFPTQFQELARAGAEIIVVPTSWQDG 214
>UniRef50_Q5NN79 Cluster: Nitrilase; n=17; Proteobacteria|Rep:
Nitrilase - Zymomonas mobilis
Length = 329
Score = 46.0 bits (104), Expect = 0.002
Identities = 45/203 (22%), Positives = 85/203 (41%), Gaps = 15/203 (7%)
Query: 146 GPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGD 205
G T + A K ++ ++ER + T++ TA+ G +IGKHRK +P
Sbjct: 83 GKETARIGSFAAKMKAYLVVGVIERSEA---TLYCTALFFAPDGTLIGKHRK-LMPTA-- 136
Query: 206 FNESTYYFEGN-TGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGL 264
E + +G+ + + +T GK+ IC+ + P+ + G I P+
Sbjct: 137 -TERLVWGQGDGSTIEILDTAVGKLGAAICWENYMPVLRQVMYAGGVNIWCAPTVD---- 191
Query: 265 SEHLWAVEARNAAIANSYYTCAINRVGTES-FPNEFTSGDGKPAHKDFGHFYGSSYVTAP 323
+W V R+ A + + + T + P ++ G + G S + P
Sbjct: 192 QREIWQVSMRHIAYEGRLFVLSACQYMTRADAPADYDCIQGNDPETEL--IAGGSVIIDP 249
Query: 324 DGSRTPGLSRIKDGLLIAQVDLN 346
G+ G ++G+L+A +DL+
Sbjct: 250 MGNILAGPLYGQEGVLVADIDLS 272
>UniRef50_Q15ZG7 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=2;
Alteromonadales|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Pseudoalteromonas
atlantica (strain T6c / BAA-1087)
Length = 276
Score = 46.0 bits (104), Expect = 0.002
Identities = 39/162 (24%), Positives = 71/162 (43%), Gaps = 7/162 (4%)
Query: 140 AEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH 199
AE + GP L +A +Y + +++ + + D + ++IN+ G+ + +++K H
Sbjct: 57 AESLGDGPIQARLMGMAKQYGVWLVAGSMPLKSENPDKFTASCLLINDAGERVTEYQKIH 116
Query: 200 I--PRVGD----FNESTYYFEGNTGHPVFETKYGKVAINICYGRHHP-LNWLMFGINGAE 252
+ +V D + ES Y G+T V +T +G + + ICY P L M +
Sbjct: 117 LFDVQVADNTKTYCESKYTQAGSTLVSVPDTPFGHLGLAICYDVRFPGLFQAMAEHKALD 176
Query: 253 IVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTES 294
++ P+A E W AI N Y A + G +
Sbjct: 177 VIALPAAFTQKTGEAHWQALLSARAIENQCYLVAAGQTGVHA 218
>UniRef50_Q5DC61 Cluster: SJCHGC06938 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC06938 protein - Schistosoma
japonicum (Blood fluke)
Length = 290
Score = 46.0 bits (104), Expect = 0.002
Identities = 56/227 (24%), Positives = 94/227 (41%), Gaps = 29/227 (12%)
Query: 72 IVRLGLIQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQ-VNILCLQEAWNMPFAFCT 130
++RL L+Q + + TD + A ++ +IS A +E ++CL E + P
Sbjct: 1 MLRLALVQ--MFVGTD------KAANLKRASDLISRAVSEHSAQLVCLPECFTSPIG--A 50
Query: 131 REKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGK 190
+ +P +AEPV GP+ L+ A + + ++ + G I+N N G+
Sbjct: 51 KYFEP---YAEPVPNGPACQMLSNAAKSHKIWLVGGSISERGSDGK-IYNCCATYNPDGE 106
Query: 191 VIGKHRKNH-----IPRVGDFNES--------TYYFEGNTGHPVFETKYGKVAINICYGR 237
++G +RK H IP F ES T+ FE + +V I ICY
Sbjct: 107 LVGLYRKLHLFDIDIPGQFTFKESASLSSGKETFSFEMPLKSSENKISVIRVGIGICYDI 166
Query: 238 HHP-LNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYY 283
P L+ L G +++ P+A W + R A+ Y
Sbjct: 167 RFPELSLLYANQLGCQLLLFPAAFNPKTGSLHWELLGRARALDTQCY 213
>UniRef50_Q5C342 Cluster: SJCHGC04680 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04680 protein - Schistosoma
japonicum (Blood fluke)
Length = 238
Score = 46.0 bits (104), Expect = 0.002
Identities = 60/212 (28%), Positives = 88/212 (41%), Gaps = 30/212 (14%)
Query: 98 FEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAV 157
F + K I+ A A V I+ L E F F + + AE VL GP LA
Sbjct: 32 FNQAVKYINKAIASGVKIVFLPEC----FDFVVLSHKETLNLAE-VLKGPLVTRYCSLAA 86
Query: 158 KYDMVI-ISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHI------------PRV- 203
+ ++ I + + + D I+N+ +VIN G+++G + K H+ P +
Sbjct: 87 RENLWISLGGAHIKSSDNDDQIYNSHIVINSDGQIVGVYHKVHLFDANLNAEEITTPNIK 146
Query: 204 ----GDFNESTYYFEGNTGHPVFE-TKYGKVAINICYGRHHP--LNWLMFGINGAEIVFN 256
F ES G V E T G + + ICY P ++L + N A ++
Sbjct: 147 STCTQSFCESKVTRSGMEAPNVIENTPIGNLGLAICYDLRFPELASYLRYARN-AHVIAY 205
Query: 257 PSA--TVSGLSEHLWAVEARNAAIANSYYTCA 286
PSA T +G S H W R AI N Y A
Sbjct: 206 PSAFSTRTGESGH-WHTLLRARAIENQCYIVA 236
>UniRef50_A2R283 Cluster: Contig An13c0120, complete genome; n=2;
Aspergillus|Rep: Contig An13c0120, complete genome -
Aspergillus niger
Length = 598
Score = 46.0 bits (104), Expect = 0.002
Identities = 61/256 (23%), Positives = 99/256 (38%), Gaps = 24/256 (9%)
Query: 132 EKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKV 191
E + W + + +LT P T L + A + II E D GD + G +
Sbjct: 64 ELEDWFEHGD-ILTAPRTKALFDTAHDLAVDIIVGFAEATDT-GDHFNSCVYYHAATGSI 121
Query: 192 IGKHRKNHIPRVGDFN-----------ESTYYFEGNTGHPVFETKYGK---VAINICYGR 237
+ K+RK H+P GD E Y+ G+ G F K + + IC R
Sbjct: 122 LSKYRKVHLP--GDVEPLPDPKAVNQLEKRYFKPGDLGFQAFREKDVVDPILGMMICNDR 179
Query: 238 HHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTE--SF 295
+W +G+ G EIV T +G + W A + + +++ + S+
Sbjct: 180 RWAESWREYGLQGVEIVACGYNT-NGFAPQFWGQSADMSPQEAEELSLFHHKLVMQCHSY 238
Query: 296 PNEFTSGDGKPAHKDFGHF--YGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKD 353
N S D G + S + P+G D ++IA DL LCR K
Sbjct: 239 TNACFSVSAARCGLDDGEYPLIAGSGIVDPEGRIIAEAKTKGDEIIIADCDLGLCRAGKT 298
Query: 354 K-WGFTMTQRLDLYAQ 368
+ + F +R++ Y +
Sbjct: 299 RTFDFGRHRRVEHYGR 314
>UniRef50_Q6RWQ5 Cluster: Nitrilase; n=1; uncultured organism|Rep:
Nitrilase - uncultured organism
Length = 298
Score = 45.6 bits (103), Expect = 0.002
Identities = 47/204 (23%), Positives = 79/204 (38%), Gaps = 11/204 (5%)
Query: 146 GPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGD 205
GP L + A + D + + ERD T+WNT + G + +HRK V
Sbjct: 82 GPLARELGDAARRADAWVAIGVNERDARRPGTLWNTLLWFAPDGSLARRHRK----LVPT 137
Query: 206 FNESTYYFEG-NTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGL 264
+E T++ +G +G++ IC+ P +G + P+A
Sbjct: 138 MHERTFWGQGAGDDLEALAADFGRLGGLICWENFMPAARRRLHRDGVDFYLAPTAD---- 193
Query: 265 SEHLWAVEARNAAI-ANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAP 323
+W R A A ++ + + T FP +F + + A F G S + P
Sbjct: 194 DRDIWVAAMRTFAFEAGAFVLSPVQYLRTADFPEDFPLRE-ELADCPEVQFTGGSVICDP 252
Query: 324 DGSRTPGLSRIKDGLLIAQVDLNL 347
G+ G + +L A DL+L
Sbjct: 253 WGNLLAGPVHGGEEILYADCDLDL 276
>UniRef50_Q60BT4 Cluster: Hydrolase, carbon-nitrogen family; n=15;
Proteobacteria|Rep: Hydrolase, carbon-nitrogen family -
Methylococcus capsulatus
Length = 273
Score = 45.6 bits (103), Expect = 0.002
Identities = 36/157 (22%), Positives = 68/157 (43%), Gaps = 6/157 (3%)
Query: 140 AEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH 199
AE +GP FLA A ++ + ++ + G + + +V ++ G+ +G++ K H
Sbjct: 59 AETDGSGPIQEFLAGAAERHKVWLVGGTMPMCAGDG-RVRASCLVYDDHGRRVGRYDKIH 117
Query: 200 -----IPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIV 254
+P + + E T V ++ +G + I ICY P + G +++
Sbjct: 118 LFDVVVPGTEETYRESLTIEPGTVPLVLDSPFGALGIAICYDLRFPELFRRMAQQGLDLL 177
Query: 255 FNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVG 291
P+A + W + R A+ N YT A N+ G
Sbjct: 178 AVPAAFTARTGAAHWEILVRARAVENLCYTVASNQGG 214
>UniRef50_Q7QAW0 Cluster: ENSANGP00000011026; n=2; Culicidae|Rep:
ENSANGP00000011026 - Anopheles gambiae str. PEST
Length = 278
Score = 45.6 bits (103), Expect = 0.002
Identities = 60/267 (22%), Positives = 109/267 (40%), Gaps = 29/267 (10%)
Query: 105 ISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVII 164
I A ++ L E +N P++ T E + AE + G ++ LA++A + + ++
Sbjct: 30 IRQAKDRGARLIILPECFNSPYS--TAE---FGRHAEEIPRGETSQALAKVAAELGVYLV 84
Query: 165 SPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH-----IPRVGDFNESTYYFEGNTGH 219
+ G ++NT V G+++ K+RK H IP F ES G+
Sbjct: 85 GGTYPERE--GTRLYNTCPVFGPKGELLCKYRKLHLFDMDIPGRCTFQESAALTAGDR-L 141
Query: 220 PVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIA 279
F K+ + IC+ + P + G +++ PSA W + R A+
Sbjct: 142 ATFSIGSLKIGLGICWDKRFPELAACYRQLGCDMMIFPSAFDPYTGPLHWDLLGRARALD 201
Query: 280 NSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLL 339
N + ++ + E+ + YG S + P G R ++ + LL
Sbjct: 202 NQMFVALVSPARDPT--TEYVA-------------YGYSLMCDPWG-RVLCRAKEEQELL 245
Query: 340 IAQVDLNLCRQIKDKWGFTMTQRLDLY 366
I +DL +C +IK + +R D+Y
Sbjct: 246 ITDIDLKMCGEIKQQIPILRQKRGDIY 272
>UniRef50_Q46AW4 Cluster: Putative amidohydrolase; n=1;
Methanosarcina barkeri str. Fusaro|Rep: Putative
amidohydrolase - Methanosarcina barkeri (strain Fusaro /
DSM 804)
Length = 287
Score = 45.6 bits (103), Expect = 0.002
Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 6/107 (5%)
Query: 187 EFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYG-KVAINICYGRHHPLNWLM 245
E G + G +RK H + E+ Y+ +G++ P+ K K+ ICY P
Sbjct: 122 ESGTLAGSYRKTHPFKT----ENNYFSKGDSIEPISLKKQNLKIGFEICYDLRFPEVARK 177
Query: 246 FGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGT 292
+ G++++ +A + SEH W + A+ AI N A NR+G+
Sbjct: 178 LSLAGSDLLVTTAAFPNPRSEH-WNILAKARAIENQIPHIACNRIGS 223
>UniRef50_O25836 Cluster: Formamidase; n=17; Bacteria|Rep:
Formamidase - Helicobacter pylori (Campylobacter pylori)
Length = 334
Score = 45.6 bits (103), Expect = 0.002
Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 7/158 (4%)
Query: 146 GPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGD 205
G T A+ + + + I+ER+ +NTA++I+ G++I K+RK +
Sbjct: 82 GKETELYAKACKEAKVYGVFSIMERNPDSNKNPYNTAIIIDPQGEIILKYRK-----LFP 136
Query: 206 FNESTYYFEGNTGHPVFETKYG-KVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGL 264
+N ++ G+ G PV E G K+A+ IC+ P G + S + +
Sbjct: 137 WNPIEPWYPGDLGMPVCEGPGGSKLAVCICHDGMIPELAREAAYKGCNVYIRISGYSTQV 196
Query: 265 SEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSG 302
++ W + R+ A N YT ++N G ++ F G
Sbjct: 197 NDQ-WILTNRSNAWHNLMYTVSVNLAGYDNVFYYFGEG 233
>UniRef50_A5GU42 Cluster: Nitrilase-related protein; n=1;
Synechococcus sp. RCC307|Rep: Nitrilase-related protein
- Synechococcus sp. (strain RCC307)
Length = 305
Score = 45.2 bits (102), Expect = 0.003
Identities = 34/126 (26%), Positives = 63/126 (50%), Gaps = 16/126 (12%)
Query: 84 ISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPV 143
+S + + +Q++ + + Q + A + +L L E WN P+ + + + +FAEP+
Sbjct: 14 VSPEPQVNRQQVCHWLE-QAMTQAGTSSSPKLLMLPEVWNSPY-----QAERFAEFAEPI 67
Query: 144 -------LTGPSTVF--LAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGK 194
GPS +A+ AV + + +I+ + G I+NTA VI+ G ++ K
Sbjct: 68 PELGADLRDGPSDSLKVVADFAVSHRVSVIAGSIPECSSDG-RIFNTATVISPAGCLLAK 126
Query: 195 HRKNHI 200
HRK H+
Sbjct: 127 HRKMHL 132
>UniRef50_A4YSE7 Cluster: N-carbamoyl-D-amino acid hydrolase; n=11;
Proteobacteria|Rep: N-carbamoyl-D-amino acid hydrolase -
Bradyrhizobium sp. (strain ORS278)
Length = 318
Score = 45.2 bits (102), Expect = 0.003
Identities = 38/181 (20%), Positives = 75/181 (41%), Gaps = 14/181 (7%)
Query: 179 WNTAVVINEFGKVIGKHRKNHIPRVGDFNE-------STYYFEGNTGHPVFETKYGKVAI 231
+NTA+++++ +++ K+RK H+P + YFE G V + G + +
Sbjct: 109 YNTAILVDKDARIVSKYRKVHLPGHAEHEPWRKFQHLEKRYFEPGRGFGVADAFGGVIGM 168
Query: 232 NICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVG 291
IC R P + + G+ G E+V + G + + A + ++ + + G
Sbjct: 169 AICNDRRWPETYRVMGLQGVEMV------LIGYNTPVHNPPAPEHDDLSLFHNRLVMQSG 222
Query: 292 TESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQI 351
+ G K ++ S + AP G + D + +A+ DL+LC+
Sbjct: 223 AYQ-NGTWVIGVAKGGIEEGVDHIAGSCIIAPSGEIVAACATKGDEIALARCDLDLCKSY 281
Query: 352 K 352
K
Sbjct: 282 K 282
>UniRef50_Q5K7Z3 Cluster: Expressed protein; n=1; Filobasidiella
neoformans|Rep: Expressed protein - Cryptococcus
neoformans (Filobasidiella neoformans)
Length = 337
Score = 45.2 bits (102), Expect = 0.003
Identities = 50/215 (23%), Positives = 86/215 (40%), Gaps = 10/215 (4%)
Query: 142 PVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIP 201
P+ +GP + +++ + L ++ + NTA I+E G + G++ K ++
Sbjct: 120 PLKSGPRPSKVTLQQLEWAKYLEQHPLSSEENSTPIVKNTAFFIDEEGVLQGEYVKQNLW 179
Query: 202 RVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATV 261
E Y G VFETK+GK + IC+ HP G +I+F P+ +
Sbjct: 180 HP----EREYIVAGIEPRQVFETKWGKAGLLICWDMSHPSAAQELADLGVDIIFAPTYWM 235
Query: 262 SGLSEHLWAVEARNAAIANSYYTCAINRVG-TESFPNEFTSGDGKPAHKDFGHFYGSSYV 320
+ SE L N Y T ++ + T +F E F G S V
Sbjct: 236 ATDSEPL----IHNHPHPTDYETSVVSALCLTRAFETETVWIMCNAGGDAIEGFMGGSGV 291
Query: 321 TAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKW 355
AP R G ++ L I V+ ++ + + +
Sbjct: 292 WAPLRGRVGGCG-VEASLQIVDVETDVLKDARQTY 325
>UniRef50_A1CIE7 Cluster: Hydrolase, carbon-nitrogen family protein;
n=8; Pezizomycotina|Rep: Hydrolase, carbon-nitrogen
family protein - Aspergillus clavatus
Length = 260
Score = 45.2 bits (102), Expect = 0.003
Identities = 52/198 (26%), Positives = 84/198 (42%), Gaps = 28/198 (14%)
Query: 180 NTAVVINEFGKVIGKHRKNHI--PRVGD---FNESTYYFEGNTGHPVFETKYGKVAINIC 234
NT + I+ G + +++K H+ + D ES +G P FET G+V + IC
Sbjct: 81 NTLIWIDNKGVITQRYQKIHLFDVEIKDGPILKESASVEKGTDILPPFETPLGRVGLAIC 140
Query: 235 YGRHHPLNWLMFGINGAEIVFNPSA-TV-SGLSEHLWAVEARNAAIANSYYTCAINRVGT 292
+ P L A+I+ PSA TV +GL+ W R AI Y A + G
Sbjct: 141 FDLRFPEISLALKRQNAQIITYPSAFTVPTGLAH--WETLIRARAIETQSYVVAAAQAG- 197
Query: 293 ESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSR--IKDGLLIAQVDLNLCRQ 350
H D YG S + P G L + + + +A+VDL+L +
Sbjct: 198 --------------PHNDKRRSYGHSMIVNPWGEVVAKLGQEYHEPQIAVAEVDLDLLEK 243
Query: 351 IKDKWGFTMTQRLDLYAQ 368
++ + + +R D+Y +
Sbjct: 244 VRRE--MPLLRRTDIYPE 259
>UniRef50_Q7UWX1 Cluster: Beta-alanine synthetase; n=1; Pirellula
sp.|Rep: Beta-alanine synthetase - Rhodopirellula
baltica
Length = 303
Score = 44.8 bits (101), Expect = 0.004
Identities = 37/140 (26%), Positives = 72/140 (51%), Gaps = 13/140 (9%)
Query: 100 KVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKY 159
+++ + A+A+ I+CL E + + + + A P+ G T L+E+A K
Sbjct: 75 RIENAVEEASAKGAEIVCLPET--CLYGWVNAKAH---ELAHPI-PGKDTDALSEIAKKN 128
Query: 160 DMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGH 219
+ + + E++ GD ++++ V+I++ G++I KHRK + V S Y G++
Sbjct: 129 RVFLSVGLSEKE---GDQLYDSVVLIDDEGELILKHRKMN---VLTHLMSPPYTRGDSVE 182
Query: 220 PVFETKYGKVAINICYGRHH 239
+ ETK+G+V + IC H
Sbjct: 183 -IVETKFGRVGMLICADTFH 201
>UniRef50_Q18UY7 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=2;
Desulfitobacterium hafniense|Rep: Nitrilase/cyanide
hydratase and apolipoprotein N-acyltransferase -
Desulfitobacterium hafniense (strain DCB-2)
Length = 356
Score = 44.8 bits (101), Expect = 0.004
Identities = 40/168 (23%), Positives = 77/168 (45%), Gaps = 13/168 (7%)
Query: 132 EKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKV 191
+ Q + D + G T L + A +Y+ +I+ + +N+A +I+ G+V
Sbjct: 68 DHQYYVDHMAIDIPGEETELLGKKAKEYNAYLIAQAKVKHPEFPGRFFNSAFLIDPKGEV 127
Query: 192 IGKHRK--------NHIPR-VGDFNESTYYFEGNTGHPVFETKYGKVAINICY--GRHHP 240
I + K + +P V D Y ++ ++ + V +T+ G++ + +C H P
Sbjct: 128 ILQSYKMQVFCQEHSTVPHDVWDKWIELYGYKLDSFYSVADTEIGRIGLLVCQEGDYHEP 187
Query: 241 LNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAIN 288
L +NGAEI++ SA ++ W ++ R A+ N+ Y A N
Sbjct: 188 ARGL--AMNGAEIIYRSSAPEPAVANGWWELQNRARALDNTCYVVAPN 233
>UniRef50_A6CFF3 Cluster: Putative nitrilase; n=1; Planctomyces
maris DSM 8797|Rep: Putative nitrilase - Planctomyces
maris DSM 8797
Length = 343
Score = 44.8 bits (101), Expect = 0.004
Identities = 67/291 (23%), Positives = 114/291 (39%), Gaps = 27/291 (9%)
Query: 83 AISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQP------W 136
A++ +P+ + A EK +I AA ++ E + F + P +
Sbjct: 9 ALAHVSPVFLNKDATVEKSCSLIREAARNGAQMIVFPETYIPAFPVWCALQAPIHNHDLF 68
Query: 137 CDFAEPVLT--GPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGK 194
C+ A + GP +AE A + +M + E + IWN +I + G ++
Sbjct: 69 CELAANSIKVDGPELAQIAETARECEMFVSMGFNEGTTVSDGCIWNANALIGDDGNILCH 128
Query: 195 HRKNHIPRVGDFNESTYYFEGN-TGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEI 253
HRK V F E + G+ G V T+ G++ + IC +PL G ++
Sbjct: 129 HRK----IVPTFYEKLVWSPGDGAGLEVCATRLGRLGMLICGENTNPLARFTLLAQGEQV 184
Query: 254 VFNPSATVSGLSEHLWAV----EARNAAI----ANSYYTCAINRVGT----ESFPNEFTS 301
+ V H AV + +NA + A+S+ N V +S +
Sbjct: 185 HMSTYPPV--WPSHDPAVHENYDLKNAILIRAGAHSFEGKLFNLVAAGYLDQSAFDLLKQ 242
Query: 302 GDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIK 352
D A G G S P+G+ + + +GLL A +DL+ C + K
Sbjct: 243 RDPDSARILEGSPRGISVAIGPNGTPISEIMQADEGLLYADIDLSQCVEPK 293
>UniRef50_A3JKT7 Cluster: Acetyltransferase domain (GNAT family)
fused to predicted amidohydrolase (Nitrilase family)
protein; n=2; Alteromonadales|Rep: Acetyltransferase
domain (GNAT family) fused to predicted amidohydrolase
(Nitrilase family) protein - Marinobacter sp. ELB17
Length = 508
Score = 44.8 bits (101), Expect = 0.004
Identities = 41/142 (28%), Positives = 63/142 (44%), Gaps = 10/142 (7%)
Query: 152 LAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTY 211
++++AV Y++ II+ + I D ++N + + + G+V + RK HI +
Sbjct: 297 MSDMAVSYNINIITGSMPL--IENDRVYNVSYLCHRDGRV-DEQRKIHIT---PHERRDW 350
Query: 212 YFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNP--SATVSGLSEHLW 269
EG VFET G+VAI ICY P M +I+ P + T +G
Sbjct: 351 VIEGGNEFKVFETDAGRVAILICYDIEFPELGRMAAEQEVDIICVPFWTDTKNGYLRVRH 410
Query: 270 AVEARNAAIANSYYTCAINRVG 291
+AR AI N Y VG
Sbjct: 411 CAQAR--AIENECYVVITGSVG 430
>UniRef50_Q00Y86 Cluster: Carbon-nitrogen hydrolase; n=2;
Ostreococcus|Rep: Carbon-nitrogen hydrolase -
Ostreococcus tauri
Length = 307
Score = 44.8 bits (101), Expect = 0.004
Identities = 48/168 (28%), Positives = 70/168 (41%), Gaps = 16/168 (9%)
Query: 144 LTGPSTVFLAELAVKYDM-VIISPILERDDIHGDTIW-NTAVVINEFGKVIGK-HRKNHI 200
L GP A +A ++ M + + + ERDD GD NT V++ G + G+ +RK H+
Sbjct: 82 LDGPIVRACAAMAREHGMWMSLGGVAERDDAGGDARRRNTHVLLTPLGTIHGEPYRKIHL 141
Query: 201 PRV-------GDFNESTYYFEGN--TGHPVFETKYGKVAINICYGRHHPLNWLMFGI-NG 250
G ES + G T H T +G V +++CY P + +G
Sbjct: 142 FDAEGVGVGGGGLMESEWTAPGRELTSHA---TDFGTVGVSVCYDVRFPDVYQALRFEHG 198
Query: 251 AEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNE 298
A+I+ PSA W V R AI Y A + G S E
Sbjct: 199 ADILIVPSAFTKITGRAHWEVLLRARAIETQCYVVAAAQCGRHSETRE 246
>UniRef50_Q6KZW3 Cluster: Carbon-nitrogen hydrolase; n=1;
Picrophilus torridus|Rep: Carbon-nitrogen hydrolase -
Picrophilus torridus
Length = 239
Score = 44.8 bits (101), Expect = 0.004
Identities = 32/118 (27%), Positives = 57/118 (48%), Gaps = 7/118 (5%)
Query: 176 DTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICY 235
+ ++N + +I++ G +IG K ++ ES YY GN + VFET +GK+ I ICY
Sbjct: 72 EKLFNRSYIISD-GALIGYQDKINLY----MGESIYYNPGNKIN-VFETMHGKIGIAICY 125
Query: 236 GRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTE 293
P + GA ++ NPS + + W + + ++ N ++N V +
Sbjct: 126 DLDFPYYAKILIKKGASLILNPS-LIRYEFHNEWHLYVESRSLENRIPVISVNSVSDD 182
>UniRef50_UPI0000E472D9 Cluster: PREDICTED: similar to
Ureidopropionase, beta, partial; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar
to Ureidopropionase, beta, partial - Strongylocentrotus
purpuratus
Length = 57
Score = 44.4 bits (100), Expect = 0.005
Identities = 20/56 (35%), Positives = 31/56 (55%)
Query: 38 LFISSVAAQKAASNGFEIKAYDFPARKEECRKPRIVRLGLIQHSIAISTDNPITQQ 93
L + + A FE+K + A E+ R PR+VR+GLIQ+ I + T P+ +Q
Sbjct: 2 LALPAECAALGEKGNFEVKGHQIAAGCEQLRSPRLVRIGLIQNQIVLPTTAPVKEQ 57
>UniRef50_Q4K4P2 Cluster: Hydrolase, carbon-nitrogen family; n=5;
Bacteria|Rep: Hydrolase, carbon-nitrogen family -
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 275
Score = 44.4 bits (100), Expect = 0.005
Identities = 51/194 (26%), Positives = 83/194 (42%), Gaps = 16/194 (8%)
Query: 105 ISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVII 164
I AAA ++ L E + F R + +E L GP+ LA + +VI+
Sbjct: 32 IRQAAARGAQVVVLPELVQSGYVFSDRNEA--LALSES-LDGPTLSLWKTLAEELQVVIV 88
Query: 165 SPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFET 224
ER D + + N+A ++ G++ +RK H+ D E+ + G+ PV T
Sbjct: 89 GGFCERLD--QERVANSAALVEPEGRLT-LYRKAHL---WD-RENLIFTPGDEPPPVVAT 141
Query: 225 KYGKVAINICYGRHHPLNWLMF-GINGAEIVFNPSATVSG---LSEH-LWAVEARNAAIA 279
++G +A+ ICY P W+ + GA ++ P G L E V + A
Sbjct: 142 RFGPIAMMICYDLEFP-EWVRLPALAGAALLCAPVNWPDGPRPLGERPAEMVRVQANAAV 200
Query: 280 NSYYTCAINRVGTE 293
N + A +R G E
Sbjct: 201 NRMFIAACDRCGEE 214
>UniRef50_Q0VS65 Cluster: Carbon-nitrogen hydrolase family protein;
n=1; Alcanivorax borkumensis SK2|Rep: Carbon-nitrogen
hydrolase family protein - Alcanivorax borkumensis
(strain SK2 / ATCC 700651 / DSM 11573)
Length = 285
Score = 44.4 bits (100), Expect = 0.005
Identities = 52/227 (22%), Positives = 88/227 (38%), Gaps = 33/227 (14%)
Query: 151 FLAELAVKYDMVIIS---PILERDD---IHGDTIWNTAVVINEFGKVIGKHRKNHI---- 200
+L E A + M II P L R D + + ++ ++ G+V+G++ K H+
Sbjct: 69 WLCEQASRLGMAIIGGSIPSLTRPDGEPVPAPRVRTRSLAVSSEGQVVGRYDKLHLFDAQ 128
Query: 201 --PRVGDFNESTYYFEGNTGHPVFETKYG--KVAINICYGRHHPLNWLMFGINGAEIVFN 256
G + ES ++ G + G +V + ICY P GAE++
Sbjct: 129 VHDAQGQYRESDFF---EPGEAIVTAPLGGVQVGLAICYDLRFPALAQRLTSAGAELLVY 185
Query: 257 PSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYG 316
PSA + + W + R A+ Y N+ G S P +GH
Sbjct: 186 PSAFTAVTGKAHWELLLRATAVQTGCYVLGANQCGQHS-----------PRRASYGH--- 231
Query: 317 SSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRL 363
S + +P G L G+L+ +DL +++ + QRL
Sbjct: 232 -SMLVSPWGDVVASLGN-APGVLVTPLDLATLYELRQRMPVQQHQRL 276
>UniRef50_Q0LC17 Cluster: NAD+ synthetase; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: NAD+ synthetase -
Herpetosiphon aurantiacus ATCC 23779
Length = 622
Score = 44.4 bits (100), Expect = 0.005
Identities = 22/66 (33%), Positives = 39/66 (59%), Gaps = 1/66 (1%)
Query: 195 HRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIV 254
HRK +P G F+E+ + E F+T++G+VAI IC H L+ + ++GA+++
Sbjct: 121 HRKMFLPTYGVFDEARFV-EAGRQIAAFDTRFGRVAILICEDAWHSLSGTVAALDGAQML 179
Query: 255 FNPSAT 260
+ SA+
Sbjct: 180 YVVSAS 185
>UniRef50_A0JW88 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=2; Arthrobacter|Rep:
Nitrilase/cyanide hydratase and apolipoprotein
N-acyltransferase - Arthrobacter sp. (strain FB24)
Length = 363
Score = 44.4 bits (100), Expect = 0.005
Identities = 42/161 (26%), Positives = 72/161 (44%), Gaps = 16/161 (9%)
Query: 144 LTGPSTVFLAELAVKYDMVIISPI-LERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPR 202
+ GP T LA+ AV+ + I + + + +D+ D +N A +I+ G++I K K
Sbjct: 79 IPGPETDELAKKAVELNTYIAAELYMVKDEDFPDRHFNVAFIIDPQGEIIYKRYKATSDA 138
Query: 203 -----VGDFNESTYYFE-----GNTG-----HPVFETKYGKVAINICYGRHHPLNWLMFG 247
+G+ N + E GN PV +T+ G + IC+ +P
Sbjct: 139 YEGGMLGNMNPHDVWDEWIEKKGNGNAMDAIFPVAKTEIGNIGYAICHEGVYPEVPRGLA 198
Query: 248 INGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAIN 288
+NGAEI+ + + +W ++ R A+ NS Y A N
Sbjct: 199 MNGAEIIIRGTLIEPAVQNGMWELQNRAHAMFNSAYIVAPN 239
>UniRef50_Q88EJ9 Cluster: Carbon-nitrogen hydrolase family protein;
n=1; Pseudomonas putida KT2440|Rep: Carbon-nitrogen
hydrolase family protein - Pseudomonas putida (strain
KT2440)
Length = 273
Score = 44.0 bits (99), Expect = 0.007
Identities = 39/156 (25%), Positives = 64/156 (41%), Gaps = 6/156 (3%)
Query: 141 EPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHI 200
EP GP+ +LA ++ + + G ++NT+VV + G +G++RK H+
Sbjct: 58 EPHSGGPAYEMCKKLAQDCNVYVHTGSFYESTPDGSRVYNTSVVFDPKGNELGRYRKIHL 117
Query: 201 -----PRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVF 255
P + ES+ G T V + + K ICY P + GA+++
Sbjct: 118 FDIVTPDGMRYGESSAVAPG-TEVSVVDIEGLKYGFAICYDIRFPELFQKLVALGADVIV 176
Query: 256 NPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVG 291
P+A + W V R AI Y A + G
Sbjct: 177 LPAAFTLQTGKDHWDVLCRARAIETQCYFLAPGQTG 212
>UniRef50_A6DN63 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Lentisphaera
araneosa HTCC2155|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Lentisphaera araneosa
HTCC2155
Length = 292
Score = 44.0 bits (99), Expect = 0.007
Identities = 34/149 (22%), Positives = 65/149 (43%), Gaps = 11/149 (7%)
Query: 149 TVFLAELAVKYDMVII-SPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHI-----PR 202
T L+ L+ Y + I+ + ER + + ++N++ + + G ++ +RK H+ P
Sbjct: 87 TDLLSPLSKTYKIAIVWGGLAERQE---NKVFNSSFIFDADGHLLDVYRKTHLFQIFTPG 143
Query: 203 VGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVS 262
+E+ Y G+TG V + + I+ICY P + G +++ N +A
Sbjct: 144 KKAIDETETYEHGDTGPCVVKINDWSIGISICYDLRFP--EFLRNYAGCDLMINSAAFTK 201
Query: 263 GLSEHLWAVEARNAAIANSYYTCAINRVG 291
+ W V R A+ N Y + G
Sbjct: 202 ATGKAHWEVLMRARAVENQSYVIGSAQCG 230
>UniRef50_A6DBX4 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Caminibacter
mediatlanticus TB-2|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Caminibacter
mediatlanticus TB-2
Length = 247
Score = 44.0 bits (99), Expect = 0.007
Identities = 40/145 (27%), Positives = 63/145 (43%), Gaps = 14/145 (9%)
Query: 156 AVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEG 215
++K+D ++ +D+ I+N+A+ + G +H K H+P G F E ++F G
Sbjct: 60 SLKFDKDVVLGAAIKDE---GRIYNSALYL---GDSFHRHNKVHLPTYGVFEEGRFFFRG 113
Query: 216 NTGHPVFETKYGKVAINICYG--RHHPLNWLMFGINGAEIVFNPSAT---VSG--LSEHL 268
F TK+GK I IC +N++ IV + S G L E
Sbjct: 114 K-DFSCFNTKFGKTTIFICEDVFSGDAINFVSKQKPDLIIVISASPAREFKEGKLLIEEE 172
Query: 269 WAVEARNAAIANSYYTCAINRVGTE 293
W ++ AI + Y NRVG E
Sbjct: 173 WEALLKSMAILSGGYVAFCNRVGFE 197
>UniRef50_A0LFW1 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 271
Score = 44.0 bits (99), Expect = 0.007
Identities = 44/163 (26%), Positives = 65/163 (39%), Gaps = 20/163 (12%)
Query: 163 IISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTG-HPV 221
I++ I+E D GD ++NTA + N G+++G+ RK + VG + G
Sbjct: 67 IVAGIVESD---GDKLYNTATIFNRSGQILGRQRKRN---VGSLERNELGISPGDGLFRA 120
Query: 222 FETKYGKVAINICYG-RHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIAN 280
F T +GK+ + +C P G EI+FN S L H W A A N
Sbjct: 121 FVTDFGKIGLPVCIDFWGQPEAGRQLVDQGVEIIFNMS-VFPVLRGH-WKTGAMVRAFDN 178
Query: 281 SYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAP 323
+N + N G+ H H G S+V P
Sbjct: 179 FVPVVGVNTADYNALLN------GRRVH----HHGGGSFVIGP 211
>UniRef50_Q6C005 Cluster: Similar to sp|P47016 Saccharomyces
cerevisiae YJL126w NIT2 nitrilase; n=1; Yarrowia
lipolytica|Rep: Similar to sp|P47016 Saccharomyces
cerevisiae YJL126w NIT2 nitrilase - Yarrowia lipolytica
(Candida lipolytica)
Length = 289
Score = 44.0 bits (99), Expect = 0.007
Identities = 52/200 (26%), Positives = 85/200 (42%), Gaps = 22/200 (11%)
Query: 176 DTIWNTAVVINEFGKVIGKHRKNH-----IPRVGDFNESTYYFEGNTGHPVFETKYGKVA 230
D + NT + ++ G ++ +++K H +P ES G+ FET G V
Sbjct: 98 DRVRNTLLWLDSNGDIVNRYQKVHLFDVEVPNGPILQESKSVEPGSELPKPFETPVGTVG 157
Query: 231 INICYGRHHPLNWLMFGINGAEIVFNPSA-TVSGLSEHLWAVEARNAAIANSYYTCAINR 289
ICY P L+ GA+I+ PSA TV + H W V AR AI Y
Sbjct: 158 PAICYDIRFPELALLLRKQGAQILQFPSAFTVRTGAAH-WHVLARARAIDTQCYVMMPAL 216
Query: 290 VGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKD--GLLIAQVDLNL 347
VG + DGK + +GH + + P G+ S I +++A ++L
Sbjct: 217 VGKH-------TEDGK--RESYGH----AMIIDPWGTVLAEASDIDSSAAVIVADINLEQ 263
Query: 348 CRQIKDKWGFTMTQRLDLYA 367
++++ +R D+Y+
Sbjct: 264 LKKVRTNMPLWDQRRNDVYS 283
>UniRef50_Q4P7D2 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 352
Score = 44.0 bits (99), Expect = 0.007
Identities = 36/119 (30%), Positives = 57/119 (47%), Gaps = 7/119 (5%)
Query: 179 WNTAVVINEFGKVIGKHRKNHIPRV---GDFN--ESTYYFEGNTGHPVFETKYGKVAINI 233
+NT ++I+ G+++ ++RK H+ V G ES +G+ +T +GK+ +
Sbjct: 208 YNTQLLIDHSGEILDRYRKLHLFDVDIKGGLKILESDSTIKGDRLLTPRQTPFGKLGMLT 267
Query: 234 CYGRHHPLNWLMFGINGAEIVFNPSA-TVSGLSEHLWAVEARNAAIANSYYTCAINRVG 291
CY P L GA+++ PSA TV + H W V R AI Y A +VG
Sbjct: 268 CYDLRFPEPSLSLRRQGAQVLTYPSAFTVRTGAAH-WEVLLRARAIETQSYVLAAAQVG 325
>UniRef50_A7I641 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Candidatus
Methanoregula boonei 6A8|Rep: Nitrilase/cyanide
hydratase and apolipoprotein N-acyltransferase -
Methanoregula boonei (strain 6A8)
Length = 265
Score = 44.0 bits (99), Expect = 0.007
Identities = 28/113 (24%), Positives = 50/113 (44%), Gaps = 4/113 (3%)
Query: 180 NTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHH 239
NTA+ I+ G ++ + K H+ G +++ F TG F + ++ + ICY
Sbjct: 91 NTAIAIDRNGTILTTYAKIHLFTPGREDQA---FSPGTGLATFALEGVQIGLAICYDLRF 147
Query: 240 PLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGT 292
P + ++ G V P+A +H W + ++ A N Y +N GT
Sbjct: 148 PEIFRLYRQRGVHAVIVPAAWPKSRLKH-WELFIQSRAAENQMYIAGVNTSGT 199
>UniRef50_Q483K8 Cluster: Hydrolase, carbon-nitrogen family; n=1;
Colwellia psychrerythraea 34H|Rep: Hydrolase,
carbon-nitrogen family - Colwellia psychrerythraea
(strain 34H / ATCC BAA-681) (Vibriopsychroerythus)
Length = 248
Score = 43.6 bits (98), Expect = 0.009
Identities = 45/185 (24%), Positives = 70/185 (37%), Gaps = 26/185 (14%)
Query: 174 HGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINI 233
H +N+ I KVI HRK+ + + + F + H + + I
Sbjct: 85 HNQNFYNSCFFIKN-SKVIHNHRKSKL-----WLDDVGIFSSGSHHSIIDINGTNYGAQI 138
Query: 234 CYGRHHPLNWLMFGINGAEIVFNPSATVSGLSE-HLWAVEARNAAIANSYYTCAINRVGT 292
C+ P GAE++F P+ + H +AR AI N + NRVG
Sbjct: 139 CFELEFPEGSRALSKQGAEVIFMPNGNMHPYGNVHYVLTQAR--AIENQCFVITCNRVG- 195
Query: 293 ESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIK 352
SG G G F G S V +P G LS ++ + +DLN Q +
Sbjct: 196 --------SGHG-------GDFVGESLVVSPTGEIIKKLSSNQE-ITTITIDLNEIEQSR 239
Query: 353 DKWGF 357
+ + +
Sbjct: 240 NNYNY 244
>UniRef50_Q16A64 Cluster: Hydrolase, putative; n=1; Roseobacter
denitrificans OCh 114|Rep: Hydrolase, putative -
Roseobacter denitrificans (strain ATCC 33942 / OCh 114)
(Erythrobactersp. (strain OCh 114)) (Roseobacter
denitrificans)
Length = 261
Score = 43.6 bits (98), Expect = 0.009
Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 6/116 (5%)
Query: 180 NTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHH 239
N VVI+ G + ++ K H+ GD + + + G VF+ KV + ICY
Sbjct: 92 NACVVIDNTGTQVARYHKTHL--FGDVDRAQFS-AGAALSEVFDLAGWKVGLAICYDVEF 148
Query: 240 PLNWLMFGINGAEIVFNPSATVSGL-SEHLWAVEARNAAIANSYYTCAINRVGTES 294
P + GAE++ P+A + S + V AR A N Y N +G E+
Sbjct: 149 PELIRSLALRGAEVILTPTANMEPFDSINTRLVPAR--AEENGVYVAYCNYIGAEA 202
>UniRef50_Q0SBF1 Cluster: Probable nitrilase; n=2;
Actinomycetales|Rep: Probable nitrilase - Rhodococcus
sp. (strain RHA1)
Length = 318
Score = 43.6 bits (98), Expect = 0.009
Identities = 35/116 (30%), Positives = 57/116 (49%), Gaps = 11/116 (9%)
Query: 144 LTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRV 203
L GP + ++A D+VI E D G +N AV ++ G ++G +RK H P
Sbjct: 76 LDGPEIRRVVDMAG--DLVITLGFCEAD---GADRYNAAVTVHGDG-ILGSYRKVHQP-- 127
Query: 204 GDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSA 259
E+ Y G+ + F+T G++ + ICY + P ++GAEI+ + SA
Sbjct: 128 --LGENLCYRAGDK-YEAFDTPVGRMGMQICYDKAFPEAARTLALDGAEIITSLSA 180
>UniRef50_A6T2L9 Cluster: Nitrilase; n=1; Janthinobacterium sp.
Marseille|Rep: Nitrilase - Janthinobacterium sp. (strain
Marseille) (Minibacterium massiliensis)
Length = 355
Score = 43.6 bits (98), Expect = 0.009
Identities = 51/241 (21%), Positives = 97/241 (40%), Gaps = 19/241 (7%)
Query: 144 LTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRV 203
+ GP L E A ++ + + I E I +W+T ++I + G ++ +HRK +
Sbjct: 79 INGPEVAQLREAARRHGVFVSMGINEGTPISMGCVWDTNILIGDDGSILNRHRK----LI 134
Query: 204 GDFNESTYYFEGN-TGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEI---VFNPSA 259
E + G+ +G V +T+ G++ +C + L G + ++P
Sbjct: 135 ATHWEKLAWASGDGSGLRVVDTRIGRIGALVCGENTNALARFSLMAQGENVHISAYSPRW 194
Query: 260 TVSGLSEHLWAVEA--RNAAIANSYYTCAINRVGTESFPNE----FTSGDGKPAHKDFGH 313
E + +EA R A A ++ N V + P E + D +
Sbjct: 195 PTHPSGEVAYDLEASIRLRAGAAAFEGKMFNIVASGFLPPEAIDMISRNDPRVRRLMEEA 254
Query: 314 FYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLC---RQIKDKWGFTMTQRLDLYAQSL 370
S + PDG + ++G++ A +DL C +Q +D G+ R D++ +
Sbjct: 255 SKSVSMIMGPDGMPISDTLQDEEGIVYADIDLAKCVVPKQFQDVVGY--YNRFDVFELKV 312
Query: 371 N 371
N
Sbjct: 313 N 313
>UniRef50_A4XAH8 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=2; Salinispora|Rep:
Nitrilase/cyanide hydratase and apolipoprotein
N-acyltransferase - Salinispora tropica CNB-440
Length = 270
Score = 43.6 bits (98), Expect = 0.009
Identities = 61/217 (28%), Positives = 93/217 (42%), Gaps = 28/217 (12%)
Query: 140 AEPVLTGPSTVFLAELAVKYDM-VIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKN 198
AEPV G F A+ A + + V++ I ER + +NT +V + G + +RK
Sbjct: 54 AEPV-DGEVGRFFADAAQRLGVWVVVGSIHERGP-DPEHSYNTCLVFDRSGTLAASYRKI 111
Query: 199 HIPRVGDFNESTYYFEGNT----GHPVFETKYG-KVAINICYGRHHP-LNWLMFGINGAE 252
H+ V + Y E T PV G +V ++ICY P L + GA+
Sbjct: 112 HLYDV-EIPGRVSYLESATVAAGAQPVVVDVEGIRVGLSICYDLRFPELYRQLVTDGGAD 170
Query: 253 IVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFG 312
++ P+A + W V R AI N + A + +GD +P FG
Sbjct: 171 LLLVPAAFMLHTGRDHWEVLLRARAIENQCFVAAAAQ-----------TGDHEPRRTCFG 219
Query: 313 HFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCR 349
S V P G+ L+++ DG +A VDL+L R
Sbjct: 220 R----SMVIDPWGT---VLAQVPDGSGLAIVDLDLER 249
>UniRef50_Q81MJ4 Cluster: Hydrolase, carbon-nitrogen family; n=30;
Bacilli|Rep: Hydrolase, carbon-nitrogen family -
Bacillus anthracis
Length = 259
Score = 43.2 bits (97), Expect = 0.012
Identities = 51/203 (25%), Positives = 86/203 (42%), Gaps = 17/203 (8%)
Query: 99 EKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVK 158
E + IS A E+ +++ L E W + + D E + L E + +
Sbjct: 20 ENAKNKISEAMKERPDVIVLPELWTTGYDLTRLSEIADRDGLE------TKEKLIEWSKQ 73
Query: 159 YDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGN-T 217
Y + I+ + + G T NT V+ G+++ ++ K H+ ++ D E Y GN T
Sbjct: 74 YGVHIVGGSIAKQTEQGVT--NTMYVVTNKGELVNEYSKVHLFQLMD--EHKYLIAGNST 129
Query: 218 GHPVFETKYGKVAINICYGRHHPLNWL-MFGINGAEIVFNPSATVSGLSEHLWAVEARNA 276
G F+ + A ICY P W+ + GA+++F + H W + +
Sbjct: 130 GE--FKLDDVECAGTICYDIRFP-EWMRVHTAKGAKVLFVVAEWPLVRLAH-WRLLLQAR 185
Query: 277 AIANSYYTCAINRVGTESFPNEF 299
A+ N Y A NR G + NEF
Sbjct: 186 AVENQCYVVACNRAGKDP-NNEF 207
>UniRef50_A7I462 Cluster: Hydrolase in agr operon; n=1;
Campylobacter hominis ATCC BAA-381|Rep: Hydrolase in agr
operon - Campylobacter hominis (strain ATCC BAA-381 /
LMG 19568 / NCTC 13146 /CH001A)
Length = 256
Score = 43.2 bits (97), Expect = 0.012
Identities = 42/202 (20%), Positives = 86/202 (42%), Gaps = 13/202 (6%)
Query: 98 FEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAV 157
+EKV + A +++ +I+ L E ++ F F ++ + + D + F E V
Sbjct: 19 YEKVLNFMQDAISKKTDIIVLPELFDTGF-FPSKNLEKFADKNAFRAREIFSNFARENCV 77
Query: 158 KYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNT 217
++ I E + D ++N + + ++ GK+I + K H+ G+ ES +
Sbjct: 78 N---IVAGSICE---MRNDKLFNASYIFDKNGKIIANYDKIHLFSTGNEKESEIF---TP 128
Query: 218 GHPVFETKYGKV--AINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARN 275
G + + ++ I ICY + + G ++F + +H + + A+
Sbjct: 129 GEKIISFRLNEIPCGIMICYDLRFAEIAKILALRGISVLFVVAQWPLKRIKH-FEILAKA 187
Query: 276 AAIANSYYTCAINRVGTESFPN 297
AI N ++ CA+N G N
Sbjct: 188 RAIENEFFVCALNGFGNSILIN 209
>UniRef50_A6BC88 Cluster: Carbon-nitrogen hydrolase family protein;
n=1; Vibrio parahaemolyticus AQ3810|Rep: Carbon-nitrogen
hydrolase family protein - Vibrio parahaemolyticus
AQ3810
Length = 162
Score = 43.2 bits (97), Expect = 0.012
Identities = 36/125 (28%), Positives = 55/125 (44%), Gaps = 18/125 (14%)
Query: 248 INGAEIVFNPSATVSGL------SEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTS 301
++GAE +F P+A S S W + + AN A NRVGTE T+
Sbjct: 42 LHGAEAIFYPTAIGSEPQDPTLDSRDHWQRTMQGHSAANLVPVIASNRVGTEVDDGIETT 101
Query: 302 GDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQ 361
FYGSS++T G++ R + ++ A++DL + + WG +
Sbjct: 102 ------------FYGSSFITDHTGAKIAEAPREGETIIYAEIDLAATAKARHAWGLFRDR 149
Query: 362 RLDLY 366
R DLY
Sbjct: 150 RPDLY 154
>UniRef50_A4EUM3 Cluster: Putative carbon-nitrogen hydrolase; n=2;
Rhodobacterales|Rep: Putative carbon-nitrogen hydrolase
- Roseobacter sp. SK209-2-6
Length = 282
Score = 43.2 bits (97), Expect = 0.012
Identities = 45/161 (27%), Positives = 72/161 (44%), Gaps = 7/161 (4%)
Query: 138 DFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRK 197
D AEP L G S ++A+++ V +S R G I V+ G+++G + K
Sbjct: 70 DLAEP-LDGASFQAWRQVAIEHG-VSVSFGFARAGEGGPFICTG--VVGPDGQLVGHYDK 125
Query: 198 NHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHP-LNWLMFGINGAEIVFN 256
H+ + G E Y+ GN VFE K++ ICY P L + +G + + +
Sbjct: 126 LHLAQYGASMEKEYFHRGNHLF-VFEINGFKLSPIICYDIRIPELARTLVIDHGVDAILH 184
Query: 257 PSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPN 297
A S H W A A+ N + ++NR G E++ N
Sbjct: 185 CGAYYRDKSFHTWHPFAIARALENQVFFLSLNRAG-ETYGN 224
>UniRef50_Q12ZA5 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Methanococcoides
burtonii DSM 6242|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Methanococcoides
burtonii (strain DSM 6242)
Length = 270
Score = 43.2 bits (97), Expect = 0.012
Identities = 45/187 (24%), Positives = 78/187 (41%), Gaps = 12/187 (6%)
Query: 108 AAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPI 167
A ++ +I+ L E ++ FC E + + AE + P+ L + K +I+ I
Sbjct: 38 AISKGADIIVLPEVFST--GFCYEELE---NIAESG-SYPTIKELEVFSKKNKCIIVGSI 91
Query: 168 LERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPV-FETKY 226
+E+ + E G+++G + K H G E Y+ G+ P+ + +
Sbjct: 92 IEKHSSKNRETYTNLGFCLEDGELVGTYTKTH--PFG--KEKEYFTSGDVIEPIHLKERD 147
Query: 227 GKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCA 286
V + ICY P ++GA+I+ A EH W A AI N + A
Sbjct: 148 LTVGLQICYEMRFPEIARKLCLSGADILMT-IAEFPNPREHQWRTLATARAIENQVFHIA 206
Query: 287 INRVGTE 293
NR G++
Sbjct: 207 CNRSGSD 213
>UniRef50_P54608 Cluster: UPF0012 hydrolase yhcX; n=12;
Bacteria|Rep: UPF0012 hydrolase yhcX - Bacillus subtilis
Length = 513
Score = 43.2 bits (97), Expect = 0.012
Identities = 46/143 (32%), Positives = 63/143 (44%), Gaps = 16/143 (11%)
Query: 154 ELAVKYDMVII--SPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTY 211
+LAVKY++ II S +E + I+N A + G I K K HI NE +
Sbjct: 305 DLAVKYNVNIIGGSHFVEEEG----KIYNIAYLFRRDG-TIEKQYKLHITP----NERKW 355
Query: 212 Y-FEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATV--SGLSEHL 268
+ VF+T GK+AI ICY P + GA+I+F P T G
Sbjct: 356 WGISAGDQVRVFDTDCGKIAIQICYDIEFPELARIAADKGAKIIFTPFCTEDRQGYLRVR 415
Query: 269 WAVEARNAAIANSYYTCAINRVG 291
+ +AR A+ N YT VG
Sbjct: 416 YCSQAR--AVENQIYTVISGTVG 436
>UniRef50_Q0S9R8 Cluster: Probable formamidase; n=1; Rhodococcus sp.
RHA1|Rep: Probable formamidase - Rhodococcus sp. (strain
RHA1)
Length = 299
Score = 42.7 bits (96), Expect = 0.016
Identities = 39/155 (25%), Positives = 66/155 (42%), Gaps = 11/155 (7%)
Query: 136 WCDFAEPVLTGPSTVFLAELAVKYDMVII-SPILERDDIHGDTIWNTAVVINEFGKVIGK 194
W D L GP + LA + + ++ + ER D D I+NTA+ ++ G+V+ +
Sbjct: 62 WMDKVALPLAGPHIDRICALAEETGLWLVPGSLYERGD--DDKIYNTAIAVSPLGEVVAR 119
Query: 195 HRKNHIPRVGDFNESTYYFEGNTGHPVFETK-YGKVAINICYGRHHPLNWLMFGINGAEI 253
+RK V + G+ VF+ G++ + ICY P GAE+
Sbjct: 120 YRK-----VFPWQPYEQTAPGSE-FVVFDIPGIGRIGLAICYDGSFPETARQLAWLGAEV 173
Query: 254 VFNPSATVSGLSEHLWAVEARNAAIANSYYTCAIN 288
+ P+ T + + V +R A N Y +N
Sbjct: 174 IIQPTLTTT-RDREMELVCSRANAWTNQVYVVNVN 207
>UniRef50_A6T0X3 Cluster: Nitrilase; n=7; Bacteria|Rep: Nitrilase -
Janthinobacterium sp. (strain Marseille) (Minibacterium
massiliensis)
Length = 316
Score = 42.7 bits (96), Expect = 0.016
Identities = 48/204 (23%), Positives = 82/204 (40%), Gaps = 17/204 (8%)
Query: 144 LTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRV 203
L GP +AE M + +ER+ T++ T + N ++GKHRK +P
Sbjct: 81 LKGPEVEAIAEATRNTGMFAVIGCIEREL---GTLYCTVLFFNGAQGLVGKHRKL-MPTA 136
Query: 204 GDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSG 263
G+ + F + PVF+T GK+ IC+ + P+ + G I P+A
Sbjct: 137 GE--RLIWGFGDGSTMPVFDTPLGKIGAVICWENYMPMLRMYMYSQGIGIYCAPTAD--- 191
Query: 264 LSEHLWAVEARNAAI-ANSYYTCAINRVGTESFP--NEFTSGDGKPAHKDFGHFYGSSYV 320
W ++ A+ + A + ++P +E GD + G S +
Sbjct: 192 -DRDTWVPSMQHIALEGRCFVLTACQYIKRSAYPATHECALGD----DPETVLMRGGSAI 246
Query: 321 TAPDGSRTPGLSRIKDGLLIAQVD 344
P G G + + LL A++D
Sbjct: 247 IDPLGKVLAGPNFEGEALLYAEID 270
>UniRef50_O94660 Cluster: Nitrilase; n=6; Ascomycota|Rep: Nitrilase
- Schizosaccharomyces pombe (Fission yeast)
Length = 276
Score = 42.7 bits (96), Expect = 0.016
Identities = 54/220 (24%), Positives = 85/220 (38%), Gaps = 24/220 (10%)
Query: 154 ELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFN-----E 208
E A K+ + + + E + + ++ + G++I ++ K H+ V N E
Sbjct: 71 ESATKHSIFVNICVHEPSKVKNKLLNSSLFIEPLHGEIISRYSKAHLFDVEIKNGPTLKE 130
Query: 209 STYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHL 268
S G P +T GKV IC+ P + GA I+ PSA
Sbjct: 131 SNTTLRGEAILPPCKTPLGKVGSAICFDIRFPEQAIKLRNMGAHIITYPSAFTEKTGAAH 190
Query: 269 WAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRT 328
W V R A+ + Y A + GK H + YG S + P G+
Sbjct: 191 WEVLLRARALDSQCYVIA-------------PAQGGK--HNEKRASYGHSMIVDPWGTVI 235
Query: 329 PGLSRIK--DGLLIAQVDLNLCRQIKDKWGFTMTQRLDLY 366
S I +GL+ A +DLNL ++ + +R DLY
Sbjct: 236 AQYSDISSPNGLIFADLDLNLVDHVRTY--IPLLRRNDLY 273
>UniRef50_A3H5Q5 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Caldivirga
maquilingensis IC-167|Rep: Nitrilase/cyanide hydratase
and apolipoprotein N-acyltransferase - Caldivirga
maquilingensis IC-167
Length = 284
Score = 42.7 bits (96), Expect = 0.016
Identities = 36/125 (28%), Positives = 66/125 (52%), Gaps = 15/125 (12%)
Query: 138 DFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRK 197
+ A+P+ GP + LA+ A + + + + + ER +G I++ AV ++ G ++ K+RK
Sbjct: 58 ELAKPI-PGPYSDALADAARESGIYVAAGLTER---YGGRIYDAAVFLSPKGDLLWKYRK 113
Query: 198 -NHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLM---FGINGAEI 253
N +P +S Y G V ET+YG++ +NIC + P N ++ GA +
Sbjct: 114 INLLPD----EQSIYEVGDRVG--VVETEYGRIGVNICID-NAPSNLVLAHSMARMGAVM 166
Query: 254 VFNPS 258
+ +PS
Sbjct: 167 ILSPS 171
>UniRef50_Q6RWN7 Cluster: Nitrilase; n=21; root|Rep: Nitrilase -
uncultured organism
Length = 353
Score = 42.3 bits (95), Expect = 0.021
Identities = 46/189 (24%), Positives = 85/189 (44%), Gaps = 12/189 (6%)
Query: 161 MVIISPILERD-DIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGH 219
+ ++ + ER+ + G +++NTA+VI G++IG+HRK + G +G+T
Sbjct: 98 VTVVIGVNERNTEASGASLYNTALVIGPLGQLIGRHRK--LVPTGPERMVWAQGDGST-L 154
Query: 220 PVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIA 279
V++T GK++ IC+ + PL GA I + + T W R+ A
Sbjct: 155 DVYDTPVGKLSTLICWENYMPLARYAMAAWGARI--HVAGTWD--RGEPWISTMRHVATE 210
Query: 280 NSYY--TCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDG 337
+ +C + + P E P +++ + G S V P G G ++G
Sbjct: 211 GRVFVISCCM-ALRKRDIPAELEFAMLYPDGREWIN-AGDSLVVNPAGQIIAGPLHEQEG 268
Query: 338 LLIAQVDLN 346
+L A+++ N
Sbjct: 269 ILYAELERN 277
>UniRef50_Q8KFB2 Cluster: Carbon-nitrogen hydrolase family protein;
n=3; Chlorobiaceae|Rep: Carbon-nitrogen hydrolase family
protein - Chlorobium tepidum
Length = 519
Score = 42.3 bits (95), Expect = 0.021
Identities = 44/157 (28%), Positives = 70/157 (44%), Gaps = 16/157 (10%)
Query: 140 AEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH 199
AEPV GPS +AE+A I+ E D G +N+A V+ + GK++ +RK
Sbjct: 62 AEPV-DGPSVQAMAEIAEAAGCYIVLGYPEIDPCTG-ICYNSAAVLGQDGKLVLNYRKVT 119
Query: 200 IPRVGDFNESTYYFEGN-TGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPS 258
E+ + G+ +FET +G+ A+ IC ++ L + GA+++ P+
Sbjct: 120 A-------EARWACPGSHMQESLFETPWGRAAVLICSDSYYGLIPRAAALRGADLLLVPA 172
Query: 259 ATVSGLSE--HLWAVEARNAAIANSYYTCAINRVGTE 293
G + LW R A N A NR G +
Sbjct: 173 NWPGGSLDPRELW----RARACENGCALVACNRTGKD 205
>UniRef50_A6W7Y4 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Kineococcus
radiotolerans SRS30216|Rep: Nitrilase/cyanide hydratase
and apolipoprotein N-acyltransferase - Kineococcus
radiotolerans SRS30216
Length = 250
Score = 42.3 bits (95), Expect = 0.021
Identities = 49/187 (26%), Positives = 77/187 (41%), Gaps = 23/187 (12%)
Query: 181 TAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHP-VFETKYGKVAINICYGRHH 239
TAVV++ G V+G++ K H+ G + F G P V E +V + +C+
Sbjct: 83 TAVVVDRDGTVLGRYVKTHL--YGPAERAA--FRPGDGTPLVVEVAGLRVGVLVCFDVEF 138
Query: 240 PLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEF 299
P + GA++V P+A L E + AR A +Y NRV +
Sbjct: 139 PETVRGLALAGADVVVVPTAI---LDESV----ARVLLPARAYE----NRVALAYANHHG 187
Query: 300 TSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTM 359
+ DG G F G S V PDG + LL+ VD + R+ ++ +
Sbjct: 188 LAADG-------GTFSGGSLVVGPDGEVLAAAGAEGEALLVVDVDADDLRRAREVVDYLP 240
Query: 360 TQRLDLY 366
+R + Y
Sbjct: 241 LRRAETY 247
>UniRef50_A5V962 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Sphingomonas
wittichii RW1|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Sphingomonas
wittichii RW1
Length = 268
Score = 42.3 bits (95), Expect = 0.021
Identities = 35/122 (28%), Positives = 52/122 (42%), Gaps = 6/122 (4%)
Query: 175 GDTIWNTAVVINEFGKVIGKHRKNH-----IPRVGDFNESTYYFEGNTGHPVFETKYGKV 229
GD NT++V + G+ IG++ K H +P ES G+ V + + KV
Sbjct: 88 GDRFLNTSLVFDRQGECIGRYSKLHRFDIDLPDGTAIRESDVVDRGD-AITVVDIEGLKV 146
Query: 230 AINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINR 289
A+ ICY P + GA+++ P+A W V R AI Y A +
Sbjct: 147 ALTICYDLRFPELFRALVDLGADLITVPAAFTFQTGADHWEVLLRARAIETECYIAAPGQ 206
Query: 290 VG 291
VG
Sbjct: 207 VG 208
>UniRef50_A5AAF3 Cluster: Contig An02c0310, complete genome; n=5;
Trichocomaceae|Rep: Contig An02c0310, complete genome -
Aspergillus niger
Length = 320
Score = 42.3 bits (95), Expect = 0.021
Identities = 28/82 (34%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Query: 178 IWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFE-GNTGHPVFETKYGKVAINICYG 236
++NTA I+ G ++G +RK +I E Y G+ H VF+T GKV + IC+
Sbjct: 104 LYNTAYFISNDGSILGHYRKKNIWHP----ERPYLTSSGHDPHEVFDTPIGKVGLLICWD 159
Query: 237 RHHPLNWLMFGINGAEIVFNPS 258
P + GAEIV P+
Sbjct: 160 LAFPEAFRELICKGAEIVVIPT 181
>UniRef50_A3DL17 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Staphylothermus
marinus F1|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Staphylothermus
marinus (strain ATCC 43588 / DSM 3639 / F1)
Length = 273
Score = 42.3 bits (95), Expect = 0.021
Identities = 31/143 (21%), Positives = 65/143 (45%), Gaps = 2/143 (1%)
Query: 152 LAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTY 211
+++LA K D ++ +E+ D T+ +++++++ G++ + K H+ + ES Y
Sbjct: 73 ISDLAAKLDTYMLIHFIEKTDTPPKTM-SSSILVHPSGRIDKVYSKMHLFDAYGYRESDY 131
Query: 212 YFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSG-LSEHLWA 270
+ G T + + + ICY P + + A VF + V G L E +
Sbjct: 132 FLPGRTLSRPLVFNHVRFYVAICYDLRFPELFRSYARKDAYGVFIHAGWVRGPLKEEILD 191
Query: 271 VEARNAAIANSYYTCAINRVGTE 293
+ AR + N+ Y ++ G +
Sbjct: 192 LLARARSHENTMYIILSDQTGKQ 214
>UniRef50_P82605 Cluster: Nitrilase; n=4; Bacteria|Rep: Nitrilase -
Bacillus sp. (strain OxB-1)
Length = 339
Score = 42.3 bits (95), Expect = 0.021
Identities = 48/180 (26%), Positives = 81/180 (45%), Gaps = 17/180 (9%)
Query: 175 GDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGH-PVFETKYGKVAINI 233
G +++ T + + G +IGKHRK E T + +G+ PVFET++G +
Sbjct: 106 GGSLYLTQLWFDPNGDLIGKHRKLKATNA----EKTIWGDGDGSMMPVFETEFGNLGGLQ 161
Query: 234 CYGRHHPLN-WLMFGINGAEIVFNPSATVSGLSE-HLWAVE-----ARNAAIANSYYTCA 286
C+ PLN M +N E V S + E HL+ E + AI+N +
Sbjct: 162 CWEHFLPLNVAAMASMN--EQVHVASWPIGMPQEGHLFGPEQCVTATKYYAISNQVFCLL 219
Query: 287 INRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPG-LSRIKDGLLIAQVDL 345
+++ TE ++ + + GH G S + AP+G L+ ++G+ A +DL
Sbjct: 220 SSQIWTEEQRDKICETEEQRNFMKVGH--GFSKIIAPNGMEIGNKLAHDEEGITYADIDL 277
>UniRef50_Q6RWP8 Cluster: Nitrilase; n=1; uncultured organism|Rep:
Nitrilase - uncultured organism
Length = 312
Score = 41.9 bits (94), Expect = 0.027
Identities = 46/202 (22%), Positives = 89/202 (44%), Gaps = 13/202 (6%)
Query: 146 GPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGD 205
GP L + ++D+V + + ER+ +++NT + + G ++ +HRK +
Sbjct: 84 GPLVDRLVDACRRHDVVCVIGVNERESERPGSLYNTMLTLGPSG-LLHRHRK----LMPT 138
Query: 206 FNESTYYFEGN-TGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGL 264
+E ++ G+ V ET G++ IC+ PL G +I P+A S
Sbjct: 139 HHERLFHGIGDGQDLGVVETDAGRIGGLICWENRMPLARYAVYQGGPQIWVAPTADDS-- 196
Query: 265 SEHLWAVEARNAAIANSYYTCAINR-VGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAP 323
W R+ AI + + ++ + + +FP++F + P + FG G++ V
Sbjct: 197 --DGWLASMRHIAIESGAFVVSVPQFIPASAFPDDFPV-ELPPGKEVFGR-GGAAIVEPT 252
Query: 324 DGSRTPGLSRIKDGLLIAQVDL 345
G G ++G++ A DL
Sbjct: 253 WGEVIAGPLYDREGIVFADCDL 274
>UniRef50_Q9ZJD8 Cluster: Putative; n=4; Helicobacter|Rep: Putative
- Helicobacter pylori J99 (Campylobacter pylori J99)
Length = 265
Score = 41.9 bits (94), Expect = 0.027
Identities = 47/210 (22%), Positives = 85/210 (40%), Gaps = 14/210 (6%)
Query: 151 FLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNEST 210
FL++ + D+++ +P+L + H A++ E + + R P ++E +
Sbjct: 61 FLSQKCEELDLIVSAPVLLEE--HSKIYKKIALISKENIQYYTQQRLIPYPH---WDEES 115
Query: 211 YYFEGNTGHP---VFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEH 267
++ + VFE ++A + H W+ G ++V S +E
Sbjct: 116 FFDNEKSAFKELLVFERDGLRIAPLFGFEAHFDEIWVQAKNQGVDVVLLSSVATFESNER 175
Query: 268 LWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSR 327
W + + A S NR+G ++ GD K ++ FYG S+V P+G+
Sbjct: 176 -WRLLCQMRAFCASCVVVRANRIG--AYRQILVEGDQK--NEFLWKFYGDSFVALPNGAI 230
Query: 328 TPGLSRIKDGLLIAQVDLNLCRQIKDKWGF 357
L K G L AQ+D N + W F
Sbjct: 231 EDSLEG-KMGALSAQMDKNDIDEWAKLWHF 259
>UniRef50_Q89XU5 Cluster: Amidohydrolase; n=48;
Alphaproteobacteria|Rep: Amidohydrolase - Bradyrhizobium
japonicum
Length = 292
Score = 41.9 bits (94), Expect = 0.027
Identities = 31/117 (26%), Positives = 47/117 (40%), Gaps = 6/117 (5%)
Query: 180 NTAVVINEFGKVIGKHRKNH-----IPRVGDFNESTYYFEGNTGHPVFETKYGKVAINIC 234
N + +I G V+ + K H +P + ES Y G T + + +G+V + IC
Sbjct: 101 NRSFLIGPEGNVLASYDKIHMFDIELPDGESYRESANYQPGETA-VISDLPWGRVGLTIC 159
Query: 235 YGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVG 291
Y P + +GA + PSA E W V R AI + A + G
Sbjct: 160 YDVRFPALYRALAESGAYFITVPSAFTRKTGEAHWHVLLRARAIETGCFVFAAAQAG 216
>UniRef50_Q0UHH3 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 357
Score = 41.9 bits (94), Expect = 0.027
Identities = 36/143 (25%), Positives = 64/143 (44%), Gaps = 8/143 (5%)
Query: 233 ICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVE-ARNAAIANSYYTCAINRVG 291
+C R W +G+ G EIV T + ++ E + A+ + + + N+ G
Sbjct: 210 LCNDRRWAEGWRSYGLQGVEIVLEGYNTTAFAPQYPGTNEWQKQEALFHHHLS---NQSG 266
Query: 292 TESFPNE-FTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQ 350
S+ N F+ GK +D G S + P+G D L+ A +DL +CR+
Sbjct: 267 --SYTNACFSIHAGKAGKEDHGSLIAGSSIVDPNGHIIAESKTEGDELVCATIDLAMCRK 324
Query: 351 IKDK-WGFTMTQRLDLYAQSLNE 372
KD+ + F +R + Y + L++
Sbjct: 325 GKDRVFDFAKHRRPERYHRLLSQ 347
>UniRef50_UPI000023E394 Cluster: hypothetical protein FG01991.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG01991.1 - Gibberella zeae PH-1
Length = 319
Score = 41.5 bits (93), Expect = 0.036
Identities = 49/181 (27%), Positives = 76/181 (41%), Gaps = 18/181 (9%)
Query: 177 TIWNTAVVINEFGKVIGKHRKNH--IPR---VGDF-----NESTYYFEGNTGHPVFETKY 226
T+ NT+ I+ G ++G + K + IP + F N S F H V +T
Sbjct: 111 TLLNTSDFIDHDGNLLGTYTKTNLWIPERLTLTSFVDHARNTSKDEFAAPNPHQVIDTPL 170
Query: 227 GKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSG-LSEHLWAVEARNAAIANSYYTC 285
G+V I +C+ P + + GA+I+ PS SG +SE A NA +
Sbjct: 171 GRVGILVCWDLAFPEAFRQLVLAGAKIIIIPSYWTSGDMSEEGLAY---NANCEKMFIQS 227
Query: 286 AINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPG-LSRIKDGLLIAQVD 344
A+ E+ G PA + F+G S VT P PG + ++ + I VD
Sbjct: 228 ALVTRAFENTAAVIYCNVGGPAEEG---FFGCSQVTLPIVGTVPGSFTDGEEAMRILNVD 284
Query: 345 L 345
+
Sbjct: 285 M 285
>UniRef50_Q2RGR0 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Moorella
thermoacetica ATCC 39073|Rep: Nitrilase/cyanide
hydratase and apolipoprotein N-acyltransferase -
Moorella thermoacetica (strain ATCC 39073)
Length = 245
Score = 41.5 bits (93), Expect = 0.036
Identities = 39/146 (26%), Positives = 61/146 (41%), Gaps = 11/146 (7%)
Query: 152 LAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTY 211
LA +A + + + I+ R + G+ ++N+A V G V +RK ++ +
Sbjct: 64 LARIARRAADLGVGLIVGRAEFAGERLFNSASVFLPDGSV-HTYRKIYLT-----DAEAR 117
Query: 212 YFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAV 271
YF TGH VF K K + IC +++P GA +F SA E W +
Sbjct: 118 YFTPGTGHLVFNYKGSKFGVIICRDQNYPELARQIAAEGARALFILSAHYYQPGEARWKL 177
Query: 272 EARNA-----AIANSYYTCAINRVGT 292
A A+ N Y N VG+
Sbjct: 178 PKNRALPIARAVENHCYVLLANAVGS 203
>UniRef50_A5FWH4 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Acidiphilium
cryptum JF-5|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Acidiphilium cryptum
(strain JF-5)
Length = 266
Score = 41.5 bits (93), Expect = 0.036
Identities = 25/85 (29%), Positives = 43/85 (50%), Gaps = 3/85 (3%)
Query: 175 GDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINIC 234
GD + N+A++I+E G +RK H+ GD + + G+ G PV + + + IC
Sbjct: 91 GDGVANSAILIDEAGGARLIYRKVHL--FGDLDRGMFALPGD-GFPVVAWRGLSLGLAIC 147
Query: 235 YGRHHPLNWLMFGINGAEIVFNPSA 259
Y P M + GA+++ P+A
Sbjct: 148 YDIEFPETARMMALAGADLILVPTA 172
>UniRef50_Q9V1L5 Cluster: Amidohydrolase, putative; n=2;
Thermococcaceae|Rep: Amidohydrolase, putative -
Pyrococcus abyssi
Length = 226
Score = 41.5 bits (93), Expect = 0.036
Identities = 33/107 (30%), Positives = 55/107 (51%), Gaps = 13/107 (12%)
Query: 128 FCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINE 187
+C + W DF+ L G +++LA + + +I +LE + ++N+A++++
Sbjct: 44 YCLTGFREW-DFSGASLYGEIVERVSKLARENSVYVIFGLLEP---YKSCVYNSALLLDR 99
Query: 188 FGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINIC 234
G+VI KHRK F E + GNT T++GKVAI IC
Sbjct: 100 NGEVILKHRK--------FQEPMKFCTGNTVKTA-RTEFGKVAIIIC 137
>UniRef50_A6QB76 Cluster: Hydrolase, carbon-nitrogen family; n=1;
Sulfurovum sp. NBC37-1|Rep: Hydrolase, carbon-nitrogen
family - Sulfurovum sp. (strain NBC37-1)
Length = 273
Score = 41.1 bits (92), Expect = 0.048
Identities = 54/227 (23%), Positives = 94/227 (41%), Gaps = 40/227 (17%)
Query: 152 LAELAVKYDMVIISPIL--ERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRV----GD 205
L LAVKYD+V I+PI+ ++D H + KV KH K + ++
Sbjct: 72 LKSLAVKYDIVFIAPIIVTKKDGYHKTIV-----------KVTPKHTKYYEQQILLPYAH 120
Query: 206 FNESTYYFEGNTGHPV-----FETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSAT 260
+NE ++ N P+ F K K+ + + H W ++V P+A+
Sbjct: 121 WNEKKFF--ANKILPLKTPMTFMIKGFKIMVMAGFELHFDPFWQAVTQKKIDLVLLPTAS 178
Query: 261 VSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYV 320
G S + W + A + + NR+G E++ + K FYG + +
Sbjct: 179 TFG-SHNRWREIIKTKAFLHGCFILRANRLG------EYSDNEVK------WKFYGDTML 225
Query: 321 TAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGF--TMTQRLDL 365
+P+G + K+ +L+ +D + + WGF + QR DL
Sbjct: 226 VSPEG-EVEMMLEDKESMLVEVIDKAQVTEHRKSWGFERELKQRQDL 271
>UniRef50_A4U2A6 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=3;
Magnetospirillum|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Magnetospirillum
gryphiswaldense
Length = 279
Score = 41.1 bits (92), Expect = 0.048
Identities = 30/127 (23%), Positives = 55/127 (43%), Gaps = 6/127 (4%)
Query: 173 IHGDTIWNTAVVINEFGKVIGKHRKNHIPRVG-----DFNESTYYFEGNTGHPVFETKYG 227
+ G + N + VI++ G ++G++ K H+ V + ES + G+ V +G
Sbjct: 94 LDGGMVANRSYVIDKNGLILGRYDKIHMFDVDLGGGESYRESATFTPGDRATMV-RLPWG 152
Query: 228 KVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAI 287
++ +++CY P + + GA + P+A W V R AI Y A
Sbjct: 153 RLGLSVCYDLRFPHLYRAYANAGAHFLAVPAAFTRTTGRAHWHVLLRARAIETGCYVFAP 212
Query: 288 NRVGTES 294
+ GT +
Sbjct: 213 AQCGTHA 219
>UniRef50_Q5ATG3 Cluster: Putative uncharacterized protein; n=3;
Dikarya|Rep: Putative uncharacterized protein -
Emericella nidulans (Aspergillus nidulans)
Length = 627
Score = 41.1 bits (92), Expect = 0.048
Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 8/144 (5%)
Query: 229 VAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVE---ARNAAIANSYYTC 285
+ + IC R +W +G+ G EIV T +G + W +R A A S +
Sbjct: 189 LGLMICNDRRWAESWRAYGLQGVEIVLCGYNT-NGFAPQFWGQSGDMSREEAEALSLFHH 247
Query: 286 AINRVGTESFPNEFTSGDGKPAHKDFGHF--YGSSYVTAPDGSRTPGLSRIKDGLLIAQV 343
+ + S+ N S D G + G S + P+G ++D +++A
Sbjct: 248 KLV-MQAHSYTNATFSVSSARCGNDDGKYPLIGGSMIVDPEGRAIAETKTVEDEVIVADC 306
Query: 344 DLNLCRQIKDK-WGFTMTQRLDLY 366
DL LC K + + F +R++ Y
Sbjct: 307 DLELCNAGKKRTFDFARHRRVEHY 330
>UniRef50_A4R649 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 521
Score = 41.1 bits (92), Expect = 0.048
Identities = 28/103 (27%), Positives = 52/103 (50%), Gaps = 12/103 (11%)
Query: 139 FAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTI-----WNTAVVINEFGKVIG 193
F EPV +G S ++ A+KY+ + E+ D + +N+ +++NE G+ +
Sbjct: 61 FLEPVGSGISALWARTTALKYNCKVAIGYPEKADSSSSFLLQGAFFNSLLMVNENGETLA 120
Query: 194 KHRKNHIPRVGDFNESTYYFEGNTG--HPVFETKYGKVAINIC 234
+RK H+ D+ + + FEG G H V + G+V + +C
Sbjct: 121 NYRKQHL----DYADKGWAFEGAGGFFHDVID-GLGRVTMGVC 158
>UniRef50_A1D103 Cluster: Hydrolase, carbon-nitrogen family protein;
n=4; Pezizomycotina|Rep: Hydrolase, carbon-nitrogen
family protein - Neosartorya fischeri (strain ATCC 1020
/ DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain
ATCC 1020 / DSM 3700 / NRRL 181))
Length = 311
Score = 41.1 bits (92), Expect = 0.048
Identities = 38/178 (21%), Positives = 72/178 (40%), Gaps = 11/178 (6%)
Query: 180 NTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHH 239
N I+ G+++G + K ++ G + + +T H V T G V + +C+
Sbjct: 115 NVTFFISNTGEILGSYVKKNL--WGPTERAYLWSSKDTPHQVISTPLGPVGLLVCWDLAF 172
Query: 240 PLNWLMFGINGAEIVFNPSA-TVSGLSEHLWAVEARNAAIANSYYTCAIN-RVGTESFPN 297
P W GA+I+ P+ T SG SE A +N + + + + R +
Sbjct: 173 PEAWRELVSQGAKIIIVPTLWTRSGASE---AGHRQNPSAPSLFLDSILTARTFENTCAV 229
Query: 298 EFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKW 355
F + G P ++ G S + P L +G+ +A VD+ + ++ +
Sbjct: 230 VFANAGGPPGR----NYCGLSQINIPYAGPLVRLGTSAEGMGVATVDMAVLEDAEENY 283
>UniRef50_UPI0000E105FE Cluster: putative hydrolase, carbon-nitrogen
family protein; n=1; alpha proteobacterium HTCC2255|Rep:
putative hydrolase, carbon-nitrogen family protein -
alpha proteobacterium HTCC2255
Length = 279
Score = 40.7 bits (91), Expect = 0.063
Identities = 48/207 (23%), Positives = 86/207 (41%), Gaps = 22/207 (10%)
Query: 152 LAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTY 211
L+++A Y + +++ + + ++ TA + G+++ ++ K H+ V + +
Sbjct: 77 LSDIAKTYHIWLVAGSIPTPSPDPNKMFATAWCFDPSGELVAQYNKTHLFDVSITDNTGT 136
Query: 212 YFEGNTGHP-----VFETKYGKVAINICYG-RHHPLNWLMFGINGAEIVFNPSATVSGLS 265
Y E T P V +T++G+V I ICY R L M N + + P+A
Sbjct: 137 YQESATTMPGSDVVVLDTEFGRVGICICYDIRFSTLFNAMVKENAIDYLVVPAAFTYQTG 196
Query: 266 EHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDG 325
+ W + AI Y A N+ G +H + H YG S + +P G
Sbjct: 197 QAHWHHLLASRAIEYQCYVIAANQGG---------------SHCNGRHTYGHSAIYSPWG 241
Query: 326 SRTPGLSRIKDGLLIAQVDLNLCRQIK 352
+ G +IA+ D N +IK
Sbjct: 242 DVLDMIEN-GAGFVIAKSDPNRHHEIK 267
>UniRef50_O66508 Cluster: Putative uncharacterized protein; n=1;
Aquifex aeolicus|Rep: Putative uncharacterized protein -
Aquifex aeolicus
Length = 246
Score = 40.7 bits (91), Expect = 0.063
Identities = 25/58 (43%), Positives = 34/58 (58%), Gaps = 4/58 (6%)
Query: 178 IWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICY 235
I NTA +I + G+VIGK K + + F+E Y+ G + VFETK GK I IC+
Sbjct: 85 ILNTAFLIED-GRVIGKRSKIKLFPI--FDEDKYFIPGKE-NKVFETKLGKAGILICF 138
>UniRef50_Q2BKP4 Cluster: Putative carbon-nitrogen hydrolase; n=1;
Neptuniibacter caesariensis|Rep: Putative
carbon-nitrogen hydrolase - Neptuniibacter caesariensis
Length = 276
Score = 40.7 bits (91), Expect = 0.063
Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 1/86 (1%)
Query: 206 FNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLS 265
+ ES Y+ G V +T G ++ICY P ++ GA I+ PSA +
Sbjct: 132 YRESDYFTPGKE-LVVEQTSVGCFGLSICYDLRFPEHYQRLADMGANIMLVPSAFTAVTG 190
Query: 266 EHLWAVEARNAAIANSYYTCAINRVG 291
+ W V R AI Y A N+ G
Sbjct: 191 KAHWEVLLRARAIETQSYVIAANQAG 216
>UniRef50_Q11M91 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Mesorhizobium sp.
BNC1|Rep: Nitrilase/cyanide hydratase and apolipoprotein
N-acyltransferase - Mesorhizobium sp. (strain BNC1)
Length = 272
Score = 40.7 bits (91), Expect = 0.063
Identities = 33/123 (26%), Positives = 50/123 (40%), Gaps = 8/123 (6%)
Query: 179 WNTAVVINEFGKVIGKHRKNH-----IPRVGDFNESTYYFEGNTGHPVFETKYGKVAINI 233
+NT+VVI GK + + K H +P + ES GN ++ V +++
Sbjct: 95 YNTSVVIGPDGKQLATYDKIHRYDVDLPSGLSYRESDTNDAGNVA-VTYDHNGTNVGLSV 153
Query: 234 CYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTE 293
CY +L GA+++ P+A W R AI Y A +VG
Sbjct: 154 CYDVRFGSLYLELAARGAQVITIPAAFTFETGAAHWDTLVRARAIETQCYVAAAGQVG-- 211
Query: 294 SFP 296
SFP
Sbjct: 212 SFP 214
>UniRef50_A3LY98 Cluster: Nitrilase superfamily member; n=3;
Saccharomycetaceae|Rep: Nitrilase superfamily member -
Pichia stipitis (Yeast)
Length = 309
Score = 40.7 bits (91), Expect = 0.063
Identities = 57/238 (23%), Positives = 93/238 (39%), Gaps = 22/238 (9%)
Query: 101 VQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYD 160
V K+I A +QV++L L EA + + +R Q + A T + F++ + +
Sbjct: 27 VNKLIQQAVQKQVSVLFLPEATD----YLSRNAQHSYELA----TSTHSKFVSVIQKQLQ 78
Query: 161 MVIISPILERDDIH-----GDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFN-----EST 210
+ +S IH G + N + ++ GK+I +++K H+ V N ES
Sbjct: 79 SLNLSDFYVAIGIHEPTEGGKRVQNNQLWLDAQGKIISRYQKIHLFDVNIKNGPILQESK 138
Query: 211 YYFEGNTG-HPV-FETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHL 268
GN P+ V + ICY P L GA I+ PSA + E
Sbjct: 139 SVEPGNKILEPLAIANSDFSVGLAICYDIRFPELALRLRKLGASIITYPSAFTTKTGEAH 198
Query: 269 WAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGS 326
W + R A+ Y + G + +G+ K YG S + P G+
Sbjct: 199 WELLGRARAVDAQSYVVMAAQSGEHDIYADRPPAEGEEVKKRIS--YGESLIIDPWGT 254
>UniRef50_Q6RWR2 Cluster: Nitrilase; n=1; uncultured organism|Rep:
Nitrilase - uncultured organism
Length = 336
Score = 40.3 bits (90), Expect = 0.083
Identities = 35/123 (28%), Positives = 54/123 (43%), Gaps = 8/123 (6%)
Query: 139 FAEPVLT--GPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHR 196
FAE +T GP T +A ++M + + ER G T++NT + G ++G+HR
Sbjct: 69 FAEQAITIPGPETECIAAACRAHNMTVAIGVTERPARAG-TLYNTLLYFGPDGMILGRHR 127
Query: 197 KNHIPRVGDFNESTYYFEGN-TGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVF 255
K + FNE + G+ T ET V IC+ PL + G +I
Sbjct: 128 K----LMPTFNERMVWGMGDGTTLRTIETPQAVVGGLICWENFMPLARTVLYTQGEQIHV 183
Query: 256 NPS 258
P+
Sbjct: 184 APT 186
>UniRef50_Q6RWE5 Cluster: Nitrilase; n=4; root|Rep: Nitrilase -
uncultured organism
Length = 332
Score = 40.3 bits (90), Expect = 0.083
Identities = 49/202 (24%), Positives = 81/202 (40%), Gaps = 12/202 (5%)
Query: 153 AELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYY 212
AEL V + + ILE T++N+ ++I+E GK+ G HRK V + E +
Sbjct: 95 AELGVVISIGVNEKILEGPG--NGTLYNSLLLIDESGKLAGHHRK----LVPTYTERMVW 148
Query: 213 FEGN-TGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAV 271
G+ G T G+V IC+ PL+ + ++G EI TV + + +
Sbjct: 149 GMGDGGGMEAISTAAGRVGGLICWEHWMPLSRQVLHMSGEEIHVAVWPTVHEVHQ----L 204
Query: 272 EARNAAIANSYYTCAIN-RVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPG 330
+R+ A + A + P E + G S V PDG
Sbjct: 205 ASRHYAFEGRCFVLAAGLLMKVRDIPPELELPSQMSRESEDWLLRGGSAVIGPDGKYIVE 264
Query: 331 LSRIKDGLLIAQVDLNLCRQIK 352
++ +L A ++L C + K
Sbjct: 265 PLFDREAILTADLELAACDREK 286
>UniRef50_Q7URE5 Cluster: Predicted amidohydrolase; n=1; Pirellula
sp.|Rep: Predicted amidohydrolase - Rhodopirellula
baltica
Length = 314
Score = 40.3 bits (90), Expect = 0.083
Identities = 39/155 (25%), Positives = 65/155 (41%), Gaps = 8/155 (5%)
Query: 140 AEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNH 199
A P + P+ L E + I L R D D + N+A++I+ G ++G++ K H
Sbjct: 87 AAPTIDSPAIGRLIEACQANRLTITIGTLIRKD--RDELHNSALMIDGSG-LLGRYNKVH 143
Query: 200 IPRVGDFNESTYYFEGNTGHPVFETKYG-KVAINICYGRHHPLNWLMFGINGAEIVFNPS 258
+P +G + G F T+ G V + ICY P G+ GA+++ +
Sbjct: 144 LPHLG---VDRFVDRGLFCDQTFTTQSGCNVGLGICYDSSFPEPMRALGLAGADVIALGT 200
Query: 259 ATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTE 293
S V ++ N + A NR+G E
Sbjct: 201 NWPVAASRTAEIVPPAR-SMENHLFFVAANRIGEE 234
>UniRef50_A2ICY3 Cluster: Cyanide hydratase; n=23;
Gammaproteobacteria|Rep: Cyanide hydratase - Pseudomonas
aeruginosa
Length = 282
Score = 40.3 bits (90), Expect = 0.083
Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 7/116 (6%)
Query: 182 AVVINEFGKVIGKHRKNHIPRV------GDFNESTYYFEGNTGHPVFETKYGKVAINICY 235
+++I+E G+ + ++ K H+ V G + ES Y G V +T G++ + +CY
Sbjct: 100 SLLIDEHGERVARYDKLHLFDVDVADARGRYRESDDYAFGQK-IVVADTPVGRLGLTVCY 158
Query: 236 GRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVG 291
P + GAE++ PSA + W V R AI Y A + G
Sbjct: 159 DLRFPELYTALREAGAELITAPSAFTAVTGAAHWQVLVRARAIETQCYLLAAGQGG 214
>UniRef50_A1HU09 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Thermosinus
carboxydivorans Nor1|Rep: Nitrilase/cyanide hydratase
and apolipoprotein N-acyltransferase - Thermosinus
carboxydivorans Nor1
Length = 275
Score = 40.3 bits (90), Expect = 0.083
Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 4/98 (4%)
Query: 208 ESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSAT---VSGL 264
E +Y G+ PVF +V +C +H+P + GAE++ P AT
Sbjct: 123 EKKHYAAGDF-LPVFALPEARVGFQLCLEQHYPEITQTLALRGAELILCPHATPRLTPAE 181
Query: 265 SEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSG 302
W + R A N Y A N VG E+ G
Sbjct: 182 RRDSWHISLRARAYDNCVYILATNMVGDNGQGVEYPGG 219
>UniRef50_A1HNR2 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=3; Firmicutes|Rep:
Nitrilase/cyanide hydratase and apolipoprotein
N-acyltransferase - Thermosinus carboxydivorans Nor1
Length = 284
Score = 40.3 bits (90), Expect = 0.083
Identities = 46/196 (23%), Positives = 80/196 (40%), Gaps = 18/196 (9%)
Query: 176 DTIWNTAVVINEFGKVIGKHRKNHIP-RVGDFNESTYYFEGNTGHP--VFETKYGKVAIN 232
+ ++N A + GK++ + + + P V ++N + GH VFET+ G +AI
Sbjct: 99 ERLYNVAHLFYPNGKIVRQPKLHITPTEVKEWNMAA-------GHDINVFETEKGTIAIL 151
Query: 233 ICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGT 292
CY P M GA+++F PS T + + AI N Y VG+
Sbjct: 152 TCYDIEFPEIVRMVRAKGADVIFCPSCTDDRHGFYRVRYTSHARAIENQVYVVTTGTVGS 211
Query: 293 ESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIK 352
+ + G+ A + + P G D ++ A +DL L +++
Sbjct: 212 LPTVDFMRANFGQAA------VITPNDIPFPPGGLLAEGEINHDMIITADLDLELLYRVR 265
Query: 353 DKWGFT--MTQRLDLY 366
++ T +R DLY
Sbjct: 266 ERGSVTTWRDRRTDLY 281
>UniRef50_A0Y2B3 Cluster: Putative hydrolase, carbon-nitrogen family
protein; n=3; Alteromonadales|Rep: Putative hydrolase,
carbon-nitrogen family protein - Alteromonadales
bacterium TW-7
Length = 279
Score = 40.3 bits (90), Expect = 0.083
Identities = 40/173 (23%), Positives = 66/173 (38%), Gaps = 23/173 (13%)
Query: 186 NEFGKVIGKHRKNHI------PRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHH 239
N G+ + + K H+ + G + ES + G+ V E+ +GK+ + +CY
Sbjct: 108 NNQGECVATYNKIHLFDVNVDDKTGSYRESDFTQAGSDV-VVVESPFGKLGLTVCYDLRF 166
Query: 240 PLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEF 299
+ GAE++ PSA + W AI Y A + GT
Sbjct: 167 SALFTALARKGAEVILVPSAFTMVTGQAHWQPLLAARAIETQCYVVAAAQYGT------- 219
Query: 300 TSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIK 352
H++ YG S + +P GS L G + A DL ++I+
Sbjct: 220 --------HENGRQTYGHSIIISPWGSTLSNLP-CGTGFISANADLEPLQKIR 263
>UniRef50_Q7VGG9 Cluster: Putative uncharacterized protein; n=1;
Helicobacter hepaticus|Rep: Putative uncharacterized
protein - Helicobacter hepaticus
Length = 259
Score = 39.9 bits (89), Expect = 0.11
Identities = 61/262 (23%), Positives = 105/262 (40%), Gaps = 25/262 (9%)
Query: 100 KVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKY 159
K++K A++V ++ L E PF F + + A L+ + L +L+ KY
Sbjct: 17 KLEKYFQTCKAKKVKLVALGEYVLNPF-FKEFDTTNPKEMAH-TLSADTLSVLHKLSKKY 74
Query: 160 DMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGH 219
+ II+P+L R+ + A++ N+ + + + P +NE ++ +
Sbjct: 75 KLDIIAPLLMRE--QNKLYKSIALIQNDKAQFYHQQKLIAYPH---WNEKAFFDNKVSKS 129
Query: 220 P----VFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARN 275
P +FE K+ I + H WL ++VF P + S+ W +
Sbjct: 130 PQTPLIFEKDGFKIGIVAGFEIHFDEIWLKLKKAQVDVVFLPCSNTFN-SKMRWRNLCQM 188
Query: 276 AAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIK 335
A NS INRVG + E T FYG S +G L K
Sbjct: 189 RAFLNSMAILRINRVGELYY--EQTP----------WRFYGDSLFINANGHIEESLGD-K 235
Query: 336 DGLLIAQVDLNLCRQIKDKWGF 357
+ +++ +DL QI+ +W F
Sbjct: 236 EEMMLVGLDLTHIHQIQKEWQF 257
>UniRef50_A3JK79 Cluster: Predicted amidohydrolase; n=3;
Gammaproteobacteria|Rep: Predicted amidohydrolase -
Marinobacter sp. ELB17
Length = 280
Score = 39.9 bits (89), Expect = 0.11
Identities = 39/155 (25%), Positives = 63/155 (40%), Gaps = 12/155 (7%)
Query: 151 FLAELAVKYDMVIIS---PILERDD--IHGDTIWNTAVVINEFGKVIGKHRKNHI----- 200
FLA+ A + I+ P+ R D + D + + +V N+ G + ++ K H+
Sbjct: 73 FLAQQAKTLKIWIVGGSLPLALRPDGSVMADRVRASCLVFNDLGDEVARYDKIHLFDAQV 132
Query: 201 -PRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSA 259
G + ES + G+ V +T G++ + +CY P + GA+ V PSA
Sbjct: 133 DDAHGQYRESDTFEAGDQVVTV-DTPAGRLGLAVCYDLRFPELFRALRDKGADWVCLPSA 191
Query: 260 TVSGLSEHLWAVEARNAAIANSYYTCAINRVGTES 294
W R AI N Y A + G S
Sbjct: 192 FTWKTGNAHWHALIRARAIENQLYVVAAGQGGHNS 226
>UniRef50_A1IFV0 Cluster: Putative hydrolase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: Putative hydrolase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 272
Score = 39.9 bits (89), Expect = 0.11
Identities = 36/143 (25%), Positives = 58/143 (40%), Gaps = 11/143 (7%)
Query: 152 LAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGDFNESTY 211
L+ +A +D+VI++ + + G + +VI+ G G + K HI E
Sbjct: 71 LSRMATAFDIVILAGTVA--EAAGGRVTACHLVISPNGSA-GGYTKLHIAPP----EKQL 123
Query: 212 YFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEH---L 268
+ G P+FE K + +CY H P + GA+I+F P A+ E
Sbjct: 124 FVPGRKV-PLFEAKGAVFGVQLCYDAHFPELSTAMALKGADILFVPHASPRNTPEEKLAS 182
Query: 269 WAVEARNAAIANSYYTCAINRVG 291
W A N + A N+ G
Sbjct: 183 WMRHLPARAYDNGVFVAACNQAG 205
>UniRef50_A0J1U1 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Shewanella woodyi
ATCC 51908|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Shewanella woodyi
ATCC 51908
Length = 288
Score = 39.9 bits (89), Expect = 0.11
Identities = 25/111 (22%), Positives = 54/111 (48%), Gaps = 8/111 (7%)
Query: 144 LTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRV 203
+ G T L ++A + + +++ + E D G++ ++T+ +I+ G +IGK+R+ H
Sbjct: 64 IPGECTDKLCQIAKEGGIYLVAGLFEVD---GESYFSTSFLISPTGNIIGKYRRVHC--- 117
Query: 204 GDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIV 254
F Y + PVF T G++ + Y + P++ + +I+
Sbjct: 118 --FEMERKYISQGSDFPVFNTDIGRIGLLQGYDINFPISCMELYCKEVDII 166
>UniRef50_O76464 Cluster: Nitrilase and fragile histidine triad
fusion protein NitFhit (NFT-1 protein) [Includes:
Bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29)
(Diadenosine 5',5'''-P1,P3-triphosphate hydrolase)
(Dinucleosidetriphosphatase) (AP3A hydrolase) (AP3Aase);
Nitrilase homolog (EC 3.5.-.-)]; n=18; Eumetazoa|Rep:
Nitrilase and fragile histidine triad fusion protein
NitFhit (NFT-1 protein) [Includes:
Bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29)
(Diadenosine 5',5'''-P1,P3-triphosphate hydrolase)
(Dinucleosidetriphosphatase) (AP3A hydrolase) (AP3Aase);
Nitrilase homolog (EC 3.5.-.-)] - Drosophila
melanogaster (Fruit fly)
Length = 460
Score = 39.9 bits (89), Expect = 0.11
Identities = 63/283 (22%), Positives = 111/283 (39%), Gaps = 30/283 (10%)
Query: 91 TQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTV 150
T + A +V +++ A ++ +L L E + F + + +E L G
Sbjct: 43 TSDKAANLSQVIELVDRAKSQNACMLFLPECCD----FVGESRTQTIELSEG-LDGELMA 97
Query: 151 FLAELAVKYDMVIIS--PILERDDIHGDTIWNTAVVINEFGKVIGKHRKNHIPRVGD--- 205
ELA K + + IS + ER+D I+N V++NE G++ +RK H+ V
Sbjct: 98 QYRELA-KCNKIWISLGGVHERND---QKIFNAHVLLNEKGELAAVYRKLHMFDVTTKEV 153
Query: 206 -FNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGINGAEIVFNPSATVSGL 264
ES G T G++ + ICY ++ GA ++ PSA
Sbjct: 154 RLRESDTVTPGYCLERPVSTPVGQIGLQICYDLRFAEPAVLLRKLGANLLTYPSAFTYAT 213
Query: 265 SEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPD 324
+ W + R AI + A ++G H +G S + +P
Sbjct: 214 GKAHWEILLRARAIETQCFVVAAAQIGW---------------HNQKRQSWGHSMIVSPW 258
Query: 325 GSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLYA 367
G+ S + + A+VDL++ + + +R D+YA
Sbjct: 259 GNVLADCSEQELDIGTAEVDLSVLQSLYQTMPCFEHRRNDIYA 301
>UniRef50_UPI000023E628 Cluster: hypothetical protein FG00821.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG00821.1 - Gibberella zeae PH-1
Length = 305
Score = 39.5 bits (88), Expect = 0.15
Identities = 50/209 (23%), Positives = 78/209 (37%), Gaps = 20/209 (9%)
Query: 99 EKVQKIISAAAAEQVNILCLQEAWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVK 158
E+ K++++AA Q +L L EA + + + + AEP T L E A +
Sbjct: 20 EQCVKLVASAARGQAKVLFLPEAAD----YIASNGKESLELAEPQSTSSFVSGLREAARE 75
Query: 159 YDMVIISPILERDDI-----HGDTIWNTAVVINEFGKV--IGKHRKNHIPRVGDFNESTY 211
+ + + I RD+ I N + IN G++ + K H G ES
Sbjct: 76 HRVAVHVGIHHRDETDIGQEQSKRILNRTIYINADGQIDDTATYDKLHAFDFGKMKESDT 135
Query: 212 YFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFGING---------AEIVFNPSATVS 262
G T F+T G++ IC+ P L G A+++ PSA
Sbjct: 136 VQPGKTLTAPFDTPIGRIGSLICFDLRFPEAPLALAQPGPHSAWKNRPAQVLTYPSAFTC 195
Query: 263 GLSEHLWAVEARNAAIANSYYTCAINRVG 291
W + AI Y A +VG
Sbjct: 196 QTGPVHWETLLKARAIETQSYVIASGQVG 224
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.320 0.136 0.414
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 445,507,029
Number of Sequences: 1657284
Number of extensions: 19056301
Number of successful extensions: 35699
Number of sequences better than 10.0: 326
Number of HSP's better than 10.0 without gapping: 98
Number of HSP's successfully gapped in prelim test: 228
Number of HSP's that attempted gapping in prelim test: 35314
Number of HSP's gapped (non-prelim): 405
length of query: 385
length of database: 575,637,011
effective HSP length: 102
effective length of query: 283
effective length of database: 406,594,043
effective search space: 115066114169
effective search space used: 115066114169
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 73 (33.5 bits)
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