Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001536-TA|BGIBMGA001536-PA|IPR003010|Nitrilase/cyanide
hydratase and apolipoprotein N-acyltransferase
(385 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR456375-1|CAG30261.1| 384|Homo sapiens Em:AP000355.2 protein. 508 e-143
BC139843-1|AAI39844.2| 389|Homo sapiens UPB1 protein protein. 508 e-143
BC131703-1|AAI31704.1| 384|Homo sapiens UPB1 protein protein. 508 e-143
AF163312-1|AAF06735.1| 384|Homo sapiens beta-ureidopropionase p... 508 e-143
AB013885-1|BAA88634.1| 384|Homo sapiens beta-ureidopropionase p... 508 e-143
AF169559-1|AAF06739.1| 387|Homo sapiens beta-ureidopropionase p... 502 e-142
CR541846-1|CAG46644.1| 327|Homo sapiens NIT1 protein. 62 4e-09
CR541814-1|CAG46613.1| 327|Homo sapiens NIT1 protein. 62 4e-09
AL591806-16|CAI15379.1| 327|Homo sapiens nitrilase 1 protein. 62 4e-09
AF069987-1|AAC39907.1| 327|Homo sapiens nitrilase 1 protein. 62 4e-09
AF069984-1|AAC39901.1| 327|Homo sapiens nitrilase homolog 1 pro... 62 4e-09
BC020620-1|AAH20620.1| 276|Homo sapiens nitrilase family, membe... 60 1e-08
BC107890-1|AAI07891.1| 276|Homo sapiens nitrilase family, membe... 60 1e-08
AF284574-1|AAF87103.1| 276|Homo sapiens Nit protein 2 protein. 60 1e-08
AF260334-1|AAG44665.1| 276|Homo sapiens CUA002 protein. 60 1e-08
BC046149-1|AAH46149.1| 243|Homo sapiens NIT1 protein protein. 44 7e-04
AL591806-17|CAI15380.1| 243|Homo sapiens nitrilase 1 protein. 44 7e-04
>CR456375-1|CAG30261.1| 384|Homo sapiens Em:AP000355.2 protein.
Length = 384
Score = 508 bits (1254), Expect = e-143
Identities = 228/383 (59%), Positives = 290/383 (75%), Gaps = 1/383 (0%)
Query: 1 MASAELTSLDEVISNSLKGKELEEFNRIHYGRIDQCALFISSVAAQKAASNGFEIKAYDF 60
MA AE SL+E + L +L+E R+ YG+ + L + A + A+ FE++ Y F
Sbjct: 1 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGK-ELRKLDLPREAFEAASREDFELQGYAF 59
Query: 61 PARKEECRKPRIVRLGLIQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQE 120
A +E+ R+PRIV +GL+Q+ I + + P+ +Q A+ +++ I+ AA VNI+C QE
Sbjct: 60 EAAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQE 119
Query: 121 AWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWN 180
AW MPFAFCTREK PW +FAE GP+T F +LA +DMV++SPILERD HGD +WN
Sbjct: 120 AWTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWN 179
Query: 181 TAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHP 240
TAVVI+ G V+GK RKNHIPRVGDFNESTYY EGN GHPVF+T++G++A+NICYGRHHP
Sbjct: 180 TAVVISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHP 239
Query: 241 LNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFT 300
LNWLM+ INGAEI+FNPSAT+ LSE LW +EARNAAIAN +TCAINRVGTE FPNEFT
Sbjct: 240 LNWLMYSINGAEIIFNPSATIGALSESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFT 299
Query: 301 SGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMT 360
SGDGK AH+DFG+FYGSSYV APD SRTPGLSR +DGLL+A++DLNLC+Q+ D W F MT
Sbjct: 300 SGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMT 359
Query: 361 QRLDLYAQSLNEAIKHDYVPQVV 383
R ++YA+ L EA+K +Y P +V
Sbjct: 360 GRYEMYARELAEAVKSNYSPTIV 382
>BC139843-1|AAI39844.2| 389|Homo sapiens UPB1 protein protein.
Length = 389
Score = 508 bits (1254), Expect = e-143
Identities = 228/383 (59%), Positives = 290/383 (75%), Gaps = 1/383 (0%)
Query: 1 MASAELTSLDEVISNSLKGKELEEFNRIHYGRIDQCALFISSVAAQKAASNGFEIKAYDF 60
MA AE SL+E + L +L+E R+ YG+ + L + A + A+ FE++ Y F
Sbjct: 1 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGK-ELRKLDLPREAFEAASREDFELQGYAF 59
Query: 61 PARKEECRKPRIVRLGLIQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQE 120
A +E+ R+PRIV +GL+Q+ I + + P+ +Q A+ +++ I+ AA VNI+C QE
Sbjct: 60 EAAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQE 119
Query: 121 AWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWN 180
AW MPFAFCTREK PW +FAE GP+T F +LA +DMV++SPILERD HGD +WN
Sbjct: 120 AWTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWN 179
Query: 181 TAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHP 240
TAVVI+ G V+GK RKNHIPRVGDFNESTYY EGN GHPVF+T++G++A+NICYGRHHP
Sbjct: 180 TAVVISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHP 239
Query: 241 LNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFT 300
LNWLM+ INGAEI+FNPSAT+ LSE LW +EARNAAIAN +TCAINRVGTE FPNEFT
Sbjct: 240 LNWLMYSINGAEIIFNPSATIGALSESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFT 299
Query: 301 SGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMT 360
SGDGK AH+DFG+FYGSSYV APD SRTPGLSR +DGLL+A++DLNLC+Q+ D W F MT
Sbjct: 300 SGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMT 359
Query: 361 QRLDLYAQSLNEAIKHDYVPQVV 383
R ++YA+ L EA+K +Y P +V
Sbjct: 360 GRYEMYARELAEAVKSNYSPTIV 382
>BC131703-1|AAI31704.1| 384|Homo sapiens UPB1 protein protein.
Length = 384
Score = 508 bits (1254), Expect = e-143
Identities = 228/383 (59%), Positives = 290/383 (75%), Gaps = 1/383 (0%)
Query: 1 MASAELTSLDEVISNSLKGKELEEFNRIHYGRIDQCALFISSVAAQKAASNGFEIKAYDF 60
MA AE SL+E + L +L+E R+ YG+ + L + A + A+ FE++ Y F
Sbjct: 1 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGK-ELRKLDLPREAFEAASREDFELQGYAF 59
Query: 61 PARKEECRKPRIVRLGLIQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQE 120
A +E+ R+PRIV +GL+Q+ I + + P+ +Q A+ +++ I+ AA VNI+C QE
Sbjct: 60 EAAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQE 119
Query: 121 AWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWN 180
AW MPFAFCTREK PW +FAE GP+T F +LA +DMV++SPILERD HGD +WN
Sbjct: 120 AWTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWN 179
Query: 181 TAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHP 240
TAVVI+ G V+GK RKNHIPRVGDFNESTYY EGN GHPVF+T++G++A+NICYGRHHP
Sbjct: 180 TAVVISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHP 239
Query: 241 LNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFT 300
LNWLM+ INGAEI+FNPSAT+ LSE LW +EARNAAIAN +TCAINRVGTE FPNEFT
Sbjct: 240 LNWLMYSINGAEIIFNPSATIGALSESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFT 299
Query: 301 SGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMT 360
SGDGK AH+DFG+FYGSSYV APD SRTPGLSR +DGLL+A++DLNLC+Q+ D W F MT
Sbjct: 300 SGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMT 359
Query: 361 QRLDLYAQSLNEAIKHDYVPQVV 383
R ++YA+ L EA+K +Y P +V
Sbjct: 360 GRYEMYARELAEAVKSNYSPTIV 382
>AF163312-1|AAF06735.1| 384|Homo sapiens beta-ureidopropionase
protein.
Length = 384
Score = 508 bits (1254), Expect = e-143
Identities = 228/383 (59%), Positives = 290/383 (75%), Gaps = 1/383 (0%)
Query: 1 MASAELTSLDEVISNSLKGKELEEFNRIHYGRIDQCALFISSVAAQKAASNGFEIKAYDF 60
MA AE SL+E + L +L+E R+ YG+ + L + A + A+ FE++ Y F
Sbjct: 1 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGK-ELRKLDLPREAFEAASREDFELQGYAF 59
Query: 61 PARKEECRKPRIVRLGLIQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQE 120
A +E+ R+PRIV +GL+Q+ I + + P+ +Q A+ +++ I+ AA VNI+C QE
Sbjct: 60 EAAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQE 119
Query: 121 AWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWN 180
AW MPFAFCTREK PW +FAE GP+T F +LA +DMV++SPILERD HGD +WN
Sbjct: 120 AWTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWN 179
Query: 181 TAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHP 240
TAVVI+ G V+GK RKNHIPRVGDFNESTYY EGN GHPVF+T++G++A+NICYGRHHP
Sbjct: 180 TAVVISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHP 239
Query: 241 LNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFT 300
LNWLM+ INGAEI+FNPSAT+ LSE LW +EARNAAIAN +TCAINRVGTE FPNEFT
Sbjct: 240 LNWLMYSINGAEIIFNPSATIGALSESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFT 299
Query: 301 SGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMT 360
SGDGK AH+DFG+FYGSSYV APD SRTPGLSR +DGLL+A++DLNLC+Q+ D W F MT
Sbjct: 300 SGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMT 359
Query: 361 QRLDLYAQSLNEAIKHDYVPQVV 383
R ++YA+ L EA+K +Y P +V
Sbjct: 360 GRYEMYARELAEAVKSNYSPTIV 382
>AB013885-1|BAA88634.1| 384|Homo sapiens beta-ureidopropionase
protein.
Length = 384
Score = 508 bits (1254), Expect = e-143
Identities = 228/383 (59%), Positives = 290/383 (75%), Gaps = 1/383 (0%)
Query: 1 MASAELTSLDEVISNSLKGKELEEFNRIHYGRIDQCALFISSVAAQKAASNGFEIKAYDF 60
MA AE SL+E + L +L+E R+ YG+ + L + A + A+ FE++ Y F
Sbjct: 1 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGK-ELRKLDLPREAFEAASREDFELQGYAF 59
Query: 61 PARKEECRKPRIVRLGLIQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQE 120
A +E+ R+PRIV +GL+Q+ I + + P+ +Q A+ +++ I+ AA VNI+C QE
Sbjct: 60 EAAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQE 119
Query: 121 AWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWN 180
AW MPFAFCTREK PW +FAE GP+T F +LA +DMV++SPILERD HGD +WN
Sbjct: 120 AWTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWN 179
Query: 181 TAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHP 240
TAVVI+ G V+GK RKNHIPRVGDFNESTYY EGN GHPVF+T++G++A+NICYGRHHP
Sbjct: 180 TAVVISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHP 239
Query: 241 LNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFT 300
LNWLM+ INGAEI+FNPSAT+ LSE LW +EARNAAIAN +TCAINRVGTE FPNEFT
Sbjct: 240 LNWLMYSINGAEIIFNPSATIGALSESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFT 299
Query: 301 SGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMT 360
SGDGK AH+DFG+FYGSSYV APD SRTPGLSR +DGLL+A++DLNLC+Q+ D W F MT
Sbjct: 300 SGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMT 359
Query: 361 QRLDLYAQSLNEAIKHDYVPQVV 383
R ++YA+ L EA+K +Y P +V
Sbjct: 360 GRYEMYARELAEAVKSNYSPTIV 382
>AF169559-1|AAF06739.1| 387|Homo sapiens beta-ureidopropionase
protein.
Length = 387
Score = 502 bits (1239), Expect = e-142
Identities = 228/386 (59%), Positives = 290/386 (75%), Gaps = 4/386 (1%)
Query: 1 MASAELTSLDEVISNSLKGKELEEFNRIHYGRIDQCALFISSVAAQKAASNGFEIKAYDF 60
MA AE SL+E + L +L+E R+ YG+ + L + A + A+ FE++ Y F
Sbjct: 1 MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGK-ELRKLDLPREAFEAASREDFELQGYAF 59
Query: 61 PARKEECRKPRIVRLGLIQHSIAISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQE 120
A +E+ R+PRIV +GL+Q+ I + + P+ +Q A+ +++ I+ AA VNI+C QE
Sbjct: 60 EAAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQE 119
Query: 121 AWNMPFAFCTREKQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWN 180
AW MPFAFCTREK PW +FAE GP+T F +LA +DMV++SPILERD HGD +WN
Sbjct: 120 AWTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWN 179
Query: 181 TAVVINEFGKVIGKHRKNHIPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHP 240
TAVVI+ G V+GK RKNHIPRVGDFNESTYY EGN GHPVF+T++G++A+NICYGRHHP
Sbjct: 180 TAVVISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHP 239
Query: 241 LNWLMFGINGAEIVFNPSATVS---GLSEHLWAVEARNAAIANSYYTCAINRVGTESFPN 297
LNWLM+ INGAEI+FNPSAT+ LSE LW +EARNAAIAN +TCAINRVGTE FPN
Sbjct: 240 LNWLMYSINGAEIIFNPSATIGALRSLSESLWPIEARNAAIANHCFTCAINRVGTEHFPN 299
Query: 298 EFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGF 357
EFTSGDGK AH+DFG+FYGSSYV APD SRTPGLSR +DGLL+A++DLNLC+Q+ D W F
Sbjct: 300 EFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNF 359
Query: 358 TMTQRLDLYAQSLNEAIKHDYVPQVV 383
MT R ++YA+ L EA+K +Y P +V
Sbjct: 360 KMTGRYEMYARELAEAVKSNYSPTIV 385
>CR541846-1|CAG46644.1| 327|Homo sapiens NIT1 protein.
Length = 327
Score = 61.7 bits (143), Expect = 4e-09
Identities = 58/194 (29%), Positives = 77/194 (39%), Gaps = 21/194 (10%)
Query: 178 IWNTAVVINEFGKVIGKHRKNH-----IPRVGDFNESTYYFEGNTGHPVFETKYGKVAIN 232
I+N V++N G V+ +RK H IP G ES G + T GK+ +
Sbjct: 142 IYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVSTPAGKIGLA 201
Query: 233 ICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGT 292
+CY P L GAEI+ PSA S W V R AI Y A + G
Sbjct: 202 VCYDMRFPELSLALAQAGAEILTYPSAFGSITGPAHWEVLLRARAIETQCYVVAAAQCG- 260
Query: 293 ESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIK 352
H + YG S V P G+ S GL +A++DLN RQ++
Sbjct: 261 --------------RHHEKRASYGHSMVVDPWGTVVARCSE-GPGLCLARIDLNYLRQLR 305
Query: 353 DKWGFTMTQRLDLY 366
+R DLY
Sbjct: 306 RHLPVFQHRRPDLY 319
>CR541814-1|CAG46613.1| 327|Homo sapiens NIT1 protein.
Length = 327
Score = 61.7 bits (143), Expect = 4e-09
Identities = 58/194 (29%), Positives = 77/194 (39%), Gaps = 21/194 (10%)
Query: 178 IWNTAVVINEFGKVIGKHRKNH-----IPRVGDFNESTYYFEGNTGHPVFETKYGKVAIN 232
I+N V++N G V+ +RK H IP G ES G + T GK+ +
Sbjct: 142 IYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVSTPAGKIGLA 201
Query: 233 ICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGT 292
+CY P L GAEI+ PSA S W V R AI Y A + G
Sbjct: 202 VCYDMRFPELSLALAQAGAEILTYPSAFGSITGPAHWEVLLRARAIETQCYVVAAAQCG- 260
Query: 293 ESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIK 352
H + YG S V P G+ S GL +A++DLN RQ++
Sbjct: 261 --------------RHHEKRASYGHSMVVDPWGTVVARCSE-GPGLCLARIDLNYLRQLR 305
Query: 353 DKWGFTMTQRLDLY 366
+R DLY
Sbjct: 306 RHLPVFQHRRPDLY 319
>AL591806-16|CAI15379.1| 327|Homo sapiens nitrilase 1 protein.
Length = 327
Score = 61.7 bits (143), Expect = 4e-09
Identities = 58/194 (29%), Positives = 77/194 (39%), Gaps = 21/194 (10%)
Query: 178 IWNTAVVINEFGKVIGKHRKNH-----IPRVGDFNESTYYFEGNTGHPVFETKYGKVAIN 232
I+N V++N G V+ +RK H IP G ES G + T GK+ +
Sbjct: 142 IYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVSTPAGKIGLA 201
Query: 233 ICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGT 292
+CY P L GAEI+ PSA S W V R AI Y A + G
Sbjct: 202 VCYDMRFPELSLALAQAGAEILTYPSAFGSITGPAHWEVLLRARAIETQCYVVAAAQCG- 260
Query: 293 ESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIK 352
H + YG S V P G+ S GL +A++DLN RQ++
Sbjct: 261 --------------RHHEKRASYGHSMVVDPWGTVVARCSE-GPGLCLARIDLNYLRQLR 305
Query: 353 DKWGFTMTQRLDLY 366
+R DLY
Sbjct: 306 RHLPVFQHRRPDLY 319
>AF069987-1|AAC39907.1| 327|Homo sapiens nitrilase 1 protein.
Length = 327
Score = 61.7 bits (143), Expect = 4e-09
Identities = 58/194 (29%), Positives = 77/194 (39%), Gaps = 21/194 (10%)
Query: 178 IWNTAVVINEFGKVIGKHRKNH-----IPRVGDFNESTYYFEGNTGHPVFETKYGKVAIN 232
I+N V++N G V+ +RK H IP G ES G + T GK+ +
Sbjct: 142 IYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVSTPAGKIGLA 201
Query: 233 ICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGT 292
+CY P L GAEI+ PSA S W V R AI Y A + G
Sbjct: 202 VCYDMRFPELSLALAQAGAEILTYPSAFGSITGPAHWEVLLRARAIETQCYVVAAAQCG- 260
Query: 293 ESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIK 352
H + YG S V P G+ S GL +A++DLN RQ++
Sbjct: 261 --------------RHHEKRASYGHSMVVDPWGTVVARCSE-GPGLCLARIDLNYLRQLR 305
Query: 353 DKWGFTMTQRLDLY 366
+R DLY
Sbjct: 306 RHLPVFQHRRPDLY 319
>AF069984-1|AAC39901.1| 327|Homo sapiens nitrilase homolog 1
protein.
Length = 327
Score = 61.7 bits (143), Expect = 4e-09
Identities = 58/194 (29%), Positives = 77/194 (39%), Gaps = 21/194 (10%)
Query: 178 IWNTAVVINEFGKVIGKHRKNH-----IPRVGDFNESTYYFEGNTGHPVFETKYGKVAIN 232
I+N V++N G V+ +RK H IP G ES G + T GK+ +
Sbjct: 142 IYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVSTPAGKIGLA 201
Query: 233 ICYGRHHPLNWLMFGINGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGT 292
+CY P L GAEI+ PSA S W V R AI Y A + G
Sbjct: 202 VCYDMRFPELSLALAQAGAEILTYPSAFGSITGPAHWEVLLRARAIETQCYVVAAAQCG- 260
Query: 293 ESFPNEFTSGDGKPAHKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIK 352
H + YG S V P G+ S GL +A++DLN RQ++
Sbjct: 261 --------------RHHEKRASYGHSMVVDPWGTVVARCSE-GPGLCLARIDLNYLRQLR 305
Query: 353 DKWGFTMTQRLDLY 366
+R DLY
Sbjct: 306 RHLPVFQHRRPDLY 319
>BC020620-1|AAH20620.1| 276|Homo sapiens nitrilase family, member 2
protein.
Length = 276
Score = 60.5 bits (140), Expect = 1e-08
Identities = 75/305 (24%), Positives = 131/305 (42%), Gaps = 40/305 (13%)
Query: 74 RLGLIQHSIA-ISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTRE 132
RL LIQ I+ I +DN +T + I AA + I+ L E +N P+
Sbjct: 5 RLALIQLQISSIKSDN-VT--------RACSFIREAATQGAKIVSLPECFNSPYG----- 50
Query: 133 KQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVI 192
+ + ++AE + G ST L+E+A + + +I + +D ++NT V G ++
Sbjct: 51 AKYFPEYAEKI-PGESTQKLSEVAKECSIYLIGGSIPEED--AGKLYNTCAVFGPDGTLL 107
Query: 193 GKHRKNH-----IPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFG 247
K+RK H +P F ES G++ F+T Y +V + ICY ++
Sbjct: 108 AKYRKIHLFDIDVPGKITFQESKTLSPGDS-FSTFDTPYCRVGLGICYDMRFAELAQIYA 166
Query: 248 INGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPA 307
G +++ P A W + R+ A+ N Y V T S + D K +
Sbjct: 167 QRGCQLLVYPGAFNLTTGPAHWELLQRSRAVDNQVY------VATAS-----PARDDKAS 215
Query: 308 HKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLYA 367
+ +GH S V P G + ++ ++ + +DL +I+ + +R DLYA
Sbjct: 216 YVAWGH----STVVNPWGEAL-AKAGTEEAIVYSDIDLKKLAEIRQQIPVFRQKRSDLYA 270
Query: 368 QSLNE 372
+ +
Sbjct: 271 VEMKK 275
>BC107890-1|AAI07891.1| 276|Homo sapiens nitrilase family, member 2
protein.
Length = 276
Score = 60.1 bits (139), Expect = 1e-08
Identities = 75/305 (24%), Positives = 131/305 (42%), Gaps = 40/305 (13%)
Query: 74 RLGLIQHSIA-ISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTRE 132
RL LIQ I+ I +DN +T + I AA + I+ L E +N P+
Sbjct: 5 RLALIQLQISSIKSDN-VT--------RACSFIREAATQGAKIVSLPECFNSPYG----- 50
Query: 133 KQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVI 192
+ + ++AE + G ST L+E+A + + +I + +D ++NT V G ++
Sbjct: 51 AKYFPEYAEKI-PGESTQKLSEVAKECSIYLIGGSIPEED--AGKLYNTCAVFGPDGTLL 107
Query: 193 GKHRKNH-----IPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFG 247
K+RK H +P F ES G++ F+T Y +V + ICY ++
Sbjct: 108 AKYRKIHLFDIDVPGKITFQESKTLSPGDS-FSTFDTPYCRVGLGICYDMRFAELAQIYA 166
Query: 248 INGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPA 307
G +++ P A W + R+ A+ N Y V T S + D K +
Sbjct: 167 QRGCQLLVYPGAFNLTTGPAHWELLQRSRAVDNQVY------VATAS-----PARDDKAS 215
Query: 308 HKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLYA 367
+ +GH S V P G + ++ ++ + +DL +I+ + +R DLYA
Sbjct: 216 YVAWGH----STVVNPWG-EVLAKAGTEEAIVYSDIDLKKLAEIRQQIPVFRQKRSDLYA 270
Query: 368 QSLNE 372
+ +
Sbjct: 271 VEMKK 275
>AF284574-1|AAF87103.1| 276|Homo sapiens Nit protein 2 protein.
Length = 276
Score = 60.1 bits (139), Expect = 1e-08
Identities = 75/305 (24%), Positives = 131/305 (42%), Gaps = 40/305 (13%)
Query: 74 RLGLIQHSIA-ISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTRE 132
RL LIQ I+ I +DN +T + I AA + I+ L E +N P+
Sbjct: 5 RLALIQLQISSIKSDN-VT--------RACSFIREAATQGAKIVSLPECFNSPYG----- 50
Query: 133 KQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVI 192
+ + ++AE + G ST L+E+A + + +I + +D ++NT V G ++
Sbjct: 51 AKYFPEYAEKI-PGESTQKLSEVAKECSIYLIGGSIPEED--AGKLYNTCAVFGPDGTLL 107
Query: 193 GKHRKNH-----IPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFG 247
K+RK H +P F ES G++ F+T Y +V + ICY ++
Sbjct: 108 AKYRKIHLFDIDVPGKITFQESKTLSPGDS-FSTFDTPYCRVGLGICYDMRFAELAQIYA 166
Query: 248 INGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPA 307
G +++ P A W + R+ A+ N Y V T S + D K +
Sbjct: 167 QRGCQLLVYPGAFNLTTGPAHWELLQRSRAVDNQVY------VATAS-----PARDDKAS 215
Query: 308 HKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLYA 367
+ +GH S V P G + ++ ++ + +DL +I+ + +R DLYA
Sbjct: 216 YVAWGH----STVVNPWG-EVLAKAGTEEAIVYSDIDLKKLAEIRQQIPVFRQKRSDLYA 270
Query: 368 QSLNE 372
+ +
Sbjct: 271 VEMKK 275
>AF260334-1|AAG44665.1| 276|Homo sapiens CUA002 protein.
Length = 276
Score = 60.1 bits (139), Expect = 1e-08
Identities = 75/305 (24%), Positives = 131/305 (42%), Gaps = 40/305 (13%)
Query: 74 RLGLIQHSIA-ISTDNPITQQRLAIFEKVQKIISAAAAEQVNILCLQEAWNMPFAFCTRE 132
RL LIQ I+ I +DN +T + I AA + I+ L E +N P+
Sbjct: 5 RLALIQLQISSIKSDN-VT--------RACSFIREAATQGAKIVSLPECFNSPYG----- 50
Query: 133 KQPWCDFAEPVLTGPSTVFLAELAVKYDMVIISPILERDDIHGDTIWNTAVVINEFGKVI 192
+ + ++AE + G ST L+E+A + + +I + +D ++NT V G ++
Sbjct: 51 AKYFPEYAEKI-PGESTQKLSEVAKECSIYLIGGSIPEED--AGKLYNTCAVFGPDGTLL 107
Query: 193 GKHRKNH-----IPRVGDFNESTYYFEGNTGHPVFETKYGKVAINICYGRHHPLNWLMFG 247
K+RK H +P F ES G++ F+T Y +V + ICY ++
Sbjct: 108 AKYRKIHLFDIDVPGKITFQESKTLSPGDS-FSTFDTPYCRVGLGICYDMRFAELAQIYA 166
Query: 248 INGAEIVFNPSATVSGLSEHLWAVEARNAAIANSYYTCAINRVGTESFPNEFTSGDGKPA 307
G +++ P A W + R+ A+ N Y V T S + D K +
Sbjct: 167 QRGCQLLVYPGAFNLTTGPAHWELLQRSRAVDNQVY------VATAS-----PARDDKAS 215
Query: 308 HKDFGHFYGSSYVTAPDGSRTPGLSRIKDGLLIAQVDLNLCRQIKDKWGFTMTQRLDLYA 367
+ +GH S V P G + ++ ++ + +DL +I+ + +R DLYA
Sbjct: 216 YVAWGH----STVVNPWG-EVLAKAGTEEAIVYSDIDLKKLAEIRQQIPVFRQKRSDLYA 270
Query: 368 QSLNE 372
+ +
Sbjct: 271 VEMKK 275
>BC046149-1|AAH46149.1| 243|Homo sapiens NIT1 protein protein.
Length = 243
Score = 44.4 bits (100), Expect = 7e-04
Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Query: 178 IWNTAVVINEFGKVIGKHRKNH-----IPRVGDFNESTYYFEGNTGHPVFETKYGKVAIN 232
I+N V++N G V+ +RK H IP G ES G + T GK+ +
Sbjct: 142 IYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVSTPAGKIGLA 201
Query: 233 ICYGRHHPLNWLMFGINGAEIVFNPSA 259
+CY P L GAEI+ PSA
Sbjct: 202 VCYDMRFPELSLALAQAGAEILTYPSA 228
>AL591806-17|CAI15380.1| 243|Homo sapiens nitrilase 1 protein.
Length = 243
Score = 44.4 bits (100), Expect = 7e-04
Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Query: 178 IWNTAVVINEFGKVIGKHRKNH-----IPRVGDFNESTYYFEGNTGHPVFETKYGKVAIN 232
I+N V++N G V+ +RK H IP G ES G + T GK+ +
Sbjct: 142 IYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVSTPAGKIGLA 201
Query: 233 ICYGRHHPLNWLMFGINGAEIVFNPSA 259
+CY P L GAEI+ PSA
Sbjct: 202 VCYDMRFPELSLALAQAGAEILTYPSA 228
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.136 0.414
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 57,708,352
Number of Sequences: 224733
Number of extensions: 2468952
Number of successful extensions: 3416
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 3379
Number of HSP's gapped (non-prelim): 25
length of query: 385
length of database: 73,234,838
effective HSP length: 91
effective length of query: 294
effective length of database: 52,784,135
effective search space: 15518535690
effective search space used: 15518535690
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 66 (30.7 bits)
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